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"url": "https://www.uniprot.org/uniprotkb/Q5RI55" } ], "reference": [ { "type": "PubMed", "id": "38017520", "url": "https://glygen.org/publication/PubMed/38017520" } ] } ], "pathway": [ { "id": "dre:560952", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560952", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZAR0-1", "protein_name": "Coiled-coil domain containing 3", "gene_name": "Ccdc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLPLLLAALCLAVSPAPARACQLPSEWRPLSEGCRAELAETIVYAKVLALHPEVPGLYNYLPWHYQAGEGGLFYSAEVEMLCDQAWGSMLEVPAGSRLNLTGLGYFSCHSHTVVQDYSYFFFVRMDENYNLLPHGVNFQDAIFPDTQENRRMFSSLFQFANCSQGQQLTTFSSDWEIQEDNRLMCSSVQKALFEEEDHVKKLQQKVATLEKRNRQLRERVKKVKRSLRQARKNSRHLELVNQKLNEKLGGPGAQQHVNALGREPERAPYRHG", "length": 273 }, "evidence": [ { "id": "RGD:1559473", "url": "https://alliancegenome.org/gene/RGD:1559473#orthology", "database": "AGR" }, { "id": "MGI:1921436", "url": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5RI65-1", "uniprot_ac": "Q5RI65", "uniprot_id": "Q5RI65_DANRE", "mass": { "chemical_mass": 41776.0, "monoisotopic_mass": 41776.0 }, "refseq": { "ac": "NP_001020669", "name": "LIM homeobox transcription factor 1-alpha", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020669" }, "gene_names": [ { "name": "lmx1a", "type": "recommended", "evidence": [ { "id": "Q5RI65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ] }, { "name": "lmx1a", "type": "synonym", "evidence": [ { "id": "NP_001020669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020669" } ] }, { "name": "si:ch211-260g14.3", "type": "synonym", "evidence": [ { "id": "NP_001020669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020669" }, { "id": "Q5RI65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ] } ], "protein_names": [ { "name": "LIM homeobox transcription factor 1-alpha", "type": "synonym", "evidence": [ { "id": "NP_001020669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020669" }, { "id": "Q5RI65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RI65/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588723.2040152.1, SRR32588718.40372163.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898400, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. 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deafness type 7", "description": "" }, { "id": "MONDO:0011074", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011074", "name": "deafness, autosomal dominant 7", "description": "" }, { "id": "MIM:601412", "resource": "MIM", "url": "https://www.omim.org/entry/601412", "name": "Deafness, autosomal dominant, 7", "description": "Deafness, autosomal dominant, 7" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110591" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RI65", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "lmx1a", "url": "https://www.uniprot.org/uniprotkb/Q5RI65", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041014-332", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-332", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000020354", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000020354", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09370", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09370", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "558036", "url": "https://www.ncbi.nlm.nih.gov/gene/558036", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017970", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017970", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050453", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050453", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558036", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558036", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DGLWHEG", "url": "https://omabrowser.org/oma/group/DGLWHEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5RI65", "url": "https://www.orthodb.org/?gene=Q5RI65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24208", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24208", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24208:SF88", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24208:SF88", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00046", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00046", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001020669", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020669", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58I3G0", "url": "https://www.uniprot.org/uniprotkb/A0AC58I3G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I3G0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I3G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I3G5", "url": "https://www.uniprot.org/uniprotkb/A0AC58I3G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I3G5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I3G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I3I0", "url": "https://www.uniprot.org/uniprotkb/A0AC58I3I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I3I0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I3I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RI65", "url": "https://www.uniprot.org/uniprotkb/Q5RI65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RI65-1", "url": "https://www.uniprot.org/uniprotkb/Q5RI65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041014-332", "url": "https://zfin.org/ZDB-GENE-041014-332", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTLWIMMCQMDDTFVVFADMWRKSVCEGCNELIRDRYLLRVQDGLWHERCLHCASCREPLKDTCFLRNKTLYCKRDYQKLFVVRCQGCSEIISPSELVMRAQGSAVFHLRCFCCCVCGCRLQKGDHCVLRGDGLFCATHFHNQLASPTSSDSGKSEDIEEDNDDEDNLKTAGESNITGDVEHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLVRRQQQQKQTVCPQEKRESPSQQHTATSCGALPVELECAGSYPLPQQNLSLDSQSLKLDPFRQGLTPPQMPGDHMHPYGCDTLYDETDSDPLCHFGDCMSSSELSFLTPIDRLYSMQDSYFAS", "length": 366, "header": "tr|Q5RI65-1|Q5RI65_DANRE Isoform 1 of LIM homeobox transcription factor 1-alpha OS=Danio rerio OX=7955 GN=lmx1a PE=4 SV=1 CANONICAL=Q5RI65-1" }, "isoforms": [ { "isoform_ac": "A0AC58I3G0-1", "url": "https://www.uniprot.org/uniprotkb/Q5RI65/entry#A0AC58I3G0-1", "sequence": { "sequence": "MLFVVRCQGCSEIISPSELVMRAQGSAVFHLRCFCCCVCGCRLQKGDHCVLRGDGLFCATHFHNQLASPTSSDSGKSEDIEEDNDDEDNLKTAGESNITGDVEHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLVRRQQQQKQTVCPQEKRESPSQQHTATSCGALPVELECAGSYPLPQQNLSLDSQSLKLDPFRQGLTPPQMPGDHMHPYGCDTLYDETDSDPLCHFGDCMSSSELSFLTPIDRLYSMQDSYFAS", "length": 288, "header": "tr|A0AC58I3G0-1|A0AC58I3G0_DANRE Computationally mapped isoform of LIM homeobox transcription factor 1-alpha isoform X2 OS=Danio rerio OX=7955 GN=lmx1a PE=4 SV=1 CANONICAL=Q5RI65-1" }, "locus": {} }, { "isoform_ac": "A0AC58I3G5-1", "url": "https://www.uniprot.org/uniprotkb/Q5RI65/entry#A0AC58I3G5-1", "sequence": { "sequence": "MKTDRLFVVRCQGCSEIISPSELVMRAQGSAVFHLRCFCCCVCGCRLQKGDHCVLRGDGLFCATHFHNQLASPTSSDSGKSEDIEEDNDDEDNLKTAGESNITGDVEHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLVRRQQQQKQTVCPQEKRESPSQQHTATSCGALPVELECAGSYPLPQQNLSLDSQSLKLDPFRQGLTPPQMPGDHMHPYGCDTLYDETDSDPLCHFGDCMSSSELSFLTPIDRLYSMQDSYFAS", "length": 292, "header": "tr|A0AC58I3G5-1|A0AC58I3G5_DANRE Computationally mapped isoform of LIM homeobox transcription factor 1-alpha isoform X1 OS=Danio rerio OX=7955 GN=lmx1a PE=4 SV=1 CANONICAL=Q5RI65-1" }, "locus": {} }, { "isoform_ac": "A0AC58I3I0-1", "url": "https://www.uniprot.org/uniprotkb/Q5RI65/entry#A0AC58I3I0-1", "sequence": { "sequence": "MRAQGSAVFHLRCFCCCVCGCRLQKGDHCVLRGDGLFCATHFHNQLASPTSSDSGKSEDIEEDNDDEDNLKTAGESNITGDVEHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLVRRQQQQKQTVCPQEKRESPSQQHTATSCGALPVELECAGSYPLPQQNLSLDSQSLKLDPFRQGLTPPQMPGDHMHPYGCDTLYDETDSDPLCHFGDCMSSSELSFLTPIDRLYSMQDSYFAS", "length": 268, "header": "tr|A0AC58I3I0-1|A0AC58I3I0_DANRE Computationally mapped isoform of LIM homeobox transcription factor 1-alpha isoform X3 OS=Danio rerio OX=7955 GN=lmx1a PE=4 SV=1 CANONICAL=Q5RI65-1" }, "locus": {} }, { "isoform_ac": "Q5RI65-1", "url": "https://www.uniprot.org/uniprotkb/Q5RI65/entry#Q5RI65-1", "sequence": { "sequence": "MTLWIMMCQMDDTFVVFADMWRKSVCEGCNELIRDRYLLRVQDGLWHERCLHCASCREPLKDTCFLRNKTLYCKRDYQKLFVVRCQGCSEIISPSELVMRAQGSAVFHLRCFCCCVCGCRLQKGDHCVLRGDGLFCATHFHNQLASPTSSDSGKSEDIEEDNDDEDNLKTAGESNITGDVEHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLVRRQQQQKQTVCPQEKRESPSQQHTATSCGALPVELECAGSYPLPQQNLSLDSQSLKLDPFRQGLTPPQMPGDHMHPYGCDTLYDETDSDPLCHFGDCMSSSELSFLTPIDRLYSMQDSYFAS", "length": 366, "header": "tr|Q5RI65-1|Q5RI65_DANRE Isoform 1 of LIM homeobox transcription factor 1-alpha OS=Danio rerio OX=7955 GN=lmx1a PE=4 SV=1 CANONICAL=Q5RI65-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Integration of genomic and functional approaches reveals enhancers at LMX1A and LMX1B.", "journal": "Mol. Genet. Genomics", "date": "2013", "authors": "Burzynski Grzegorz M, Reed Xylena, Maragh Samantha, Matsui Takeshi, McCallion Andrew S", "evidence": [ { "database": "UniProtKB", "id": "Q5RI65", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ], "reference": [ { "type": "PubMed", "id": "23942840", "url": "https://glygen.org/publication/PubMed/23942840" } ] }, { "title": "Early depletion of primordial germ cells in zebrafish promotes testis formation.", "journal": "Stem Cell Reports", "date": "2015", "authors": "Tzung Keh-Weei, Goto Rie, Saju Jolly M, Sreenivasan Rajini, Saito Taiju, Arai Katsutoshi, Yamaha Etsuro, Hossain Mohammad Sorowar, Calvert Meredith E K, Orb\u00e1n L\u00e1szl\u00f3", "evidence": [ { "database": "UniProtKB", "id": "Q5RI65", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ], "reference": [ { "type": "PubMed", "id": "25434820", "url": "https://glygen.org/publication/PubMed/25434820" } ] }, { "title": "Zdhhc15b Regulates Differentiation of Diencephalic Dopaminergic Neurons in zebrafish.", "journal": "J. Cell. Biochem.", "date": "2015", "authors": "Wang Fen, Chen Xueran, Shi Wei, Yao Linli, Gao Ming, Yang Yang, Hao Aijun", "evidence": [ { "database": "UniProtKB", "id": "Q5RI65", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ], "reference": [ { "type": "PubMed", "id": "26095893", "url": "https://glygen.org/publication/PubMed/26095893" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "Q5RI65", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Molecular codes and in vitro generation of hypocretin and melanin concentrating hormone neurons.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2019", "authors": "Seifinejad A, Li S, Mikhail C, Vassalli A, Pradervand S, Arribat Y, Pezeshgi Modarres H, Allen B, John RM, Amati F, Tafti M", "evidence": [ { "database": "UniProtKB", "id": "Q5RI65", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ], "reference": [ { "type": "PubMed", "id": "31375626", "url": "https://glygen.org/publication/PubMed/31375626" } ] }, { "title": "The developmental hourglass model is applicable to the spinal cord based on single-cell transcriptomes and non-conserved cis-regulatory elements.", "journal": "Dev. Growth Differ.", "date": "2021", "authors": "Mukaigasa Katsuki, Sakuma Chie, Yaginuma Hiroyuki", "evidence": [ { "database": "UniProtKB", "id": "Q5RI65", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ], "reference": [ { "type": "PubMed", "id": "34473348", "url": "https://glygen.org/publication/PubMed/34473348" } ] } ], "pathway": [ { "id": "dre:558036", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558036", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LRJ8-1", "protein_name": "LIM homeobox transcription factor 1-alpha", "gene_name": "Lmx1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLDGLKMEENFQSAIETSASFSSLLGRAVSPKSVCEGCQRVISDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYHYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGASEDGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGSGNAGMEGIMNPYTTLPTPQQLLAIEQSVYNSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS", "length": 382 }, "evidence": [ { "id": "HGNC:6653", "url": "https://alliancegenome.org/gene/HGNC:6653#orthology", "database": "AGR" }, { "id": "MGI:1888519", "url": "https://alliancegenome.org/gene/MGI:1888519#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TE12-1", "protein_name": "LIM homeobox transcription factor 1-alpha", "gene_name": "LMX1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLDGLKMEENFQSAIDTSASFSSLLGRAVSPKSVCEGCQRVILDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYDYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGTAEEGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLSSAQTNGGGSAGMEGIMNPYTALPTPQQLLAIEQSVYSSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS", "length": 382 }, "evidence": [ { "id": "HGNC:6653", "url": "https://alliancegenome.org/gene/HGNC:6653#orthology", "database": "AGR" }, { "id": "MGI:1888519", "url": "https://alliancegenome.org/gene/MGI:1888519#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-332", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-332#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JKU8-1", "protein_name": "LIM homeobox transcription factor 1-alpha", "gene_name": "Lmx1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLDGLKMEENFQSAIETSASFSSLLGRAVSPKSVCEGCQRVISDRFLLRLNDSFWHEQCVQCASCKEPLETTCFYRDKKLYCKYHYEKLFAVKCGGCFEAIAPNEFVMRAQKSVYHLSCFCCCVCERQLQKGDEFVLKEGQLLCKGDYEKERELLSLVSPAASDSGKSDDEESLCKSAHGAGKGASEDGKDHKRPKRPRTILTTQQRRAFKASFEVSSKPCRKVRETLAAETGLSVRVVQVWFQNQRAKMKKLARRQQQQQQDQQNTQRLTSAQTNGSGNAGMEGIMNPYTTLPTPQQLLAIEQSVYNSDPFRQGLTPPQMPGDHMHPYGAEPLFHDLDSDDTSLSNLGDCFLATSEAGPLQSRVGNPIDHLYSMQNSYFTS", "length": 382 }, "evidence": [ { "id": "HGNC:6653", "url": "https://alliancegenome.org/gene/HGNC:6653#orthology", "database": "AGR" }, { "id": "MGI:1888519", "url": "https://alliancegenome.org/gene/MGI:1888519#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-332", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-332#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VTW5-1", "protein_name": "LIM homeobox transcription factor 1 alpha, isoform B", "gene_name": "Lmx1a", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLEFYPMPTNLNPVGGSLYSLQQNHGGARFLDNPNPGSMTASSGNSLHLSNSNNNLPTSISGNNSPTATASLTGQHQQHQQQQHQQQQQHPHQQHQQHQQQHAASTTPVPINSCPTPTGHSPLSSSSSNSNHNNNNNNNNGGSSSNNLHSACNTLTAAAVAAASAAAVAAPSPAGTSVATSQLGGAVAAAIAAAAAAAAAATTPTSTGPAATGSGNANGSGNGNGNGNGNGNGNGNGNGGGAATASAAAASKLSADCSGRTEVGHIKCEKNFELCEGCGQKIHDRFLMNVGDANWHEQCLACCYCGMQLHHTCYVRNSKLYCKMDYDRLFGVKCSSCCHAILPQELVMRPIPNFVFHLPCFVCYACRLPLQKGEQFMLRDGQLFCYRHDLEKEMFLAAAAAQHCGFVGLDEEDLLRPRDGRRGPKRPRTILTSQQRKQFKASFDQSPKPCRKVREALAKDTGLSVRVVQVWFQNQRAKMKKIQRKAKQNGGSGGGSGSGRGTGNSSATDDKDTNDKEDKCVKQELGGDSSGYLGGLDSTFASQPLNPNLPFSPDDYPANSNDSFCSSDLSLDGSNFDQLDDDADSLSLNNLELQSTSSSGNQHSHSHSNPHDMLANLNNSLINPIDKLYLMQNSYFSSEH", "length": 640 }, "evidence": [ { "id": "HGNC:6653", "url": "https://alliancegenome.org/gene/HGNC:6653#orthology", "database": "AGR" }, { "id": "MGI:1888519", "url": "https://alliancegenome.org/gene/MGI:1888519#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5RI65", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5RI65", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "Q5RI65", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ], "pmid": "" }, { "name": "neuron differentiation", "id": "GO:0030182", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030182", 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{ "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5RI65", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5RI65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RI65" }, { "id": "PS50071", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50071" }, { "id": "PRU00108", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00108" } ], 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Rep.", "date": "2016", "authors": "Tang Haipei, Liu Yun, Li Jianzhen, Yin Yike, Li Gaofei, Chen Yu, Li Shuisheng, Zhang Yong, Lin Haoran, Liu Xiaochun, Cheng Christopher H K", "evidence": [ { "database": "UniProtKB", "id": "Q5RI92", "url": "https://www.uniprot.org/uniprotkb/Q5RI92" } ], "reference": [ { "type": "PubMed", "id": "27333837", "url": "https://glygen.org/publication/PubMed/27333837" } ] }, { "title": "Isopropyl 3-(3,4-dihydroxyphenyl)-2-hydroxypropanoate plays an anti-hypoxic role through regulating neuroactive ligand-receptor interaction signaling pathway in larval zebrafish.", "journal": "Biomed. Pharmacother.", "date": "2023", "authors": "Zhang Siyue, Wang Xixin, Yang Qing, Xia Qing, Zhao Ye, Zheng Xiaohui, Zhang Yun, Liu Kechun", "evidence": [ { "database": "UniProtKB", "id": "Q5RI92", "url": "https://www.uniprot.org/uniprotkb/Q5RI92" } ], "reference": [ { "type": "PubMed", "id": "36948132", "url": "https://glygen.org/publication/PubMed/36948132" } ] } ], "pathway": [ { "id": "dre:570410", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570410", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7IK67-1", "protein_name": "Prostaglandin E2 receptor EP2 subtype", "gene_name": "Ptger2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": 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"tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNFLNDSKLMEDCKSRQWLLSGESPAISSVMFSAGVLGNLIALALLARRWRGDTGCSAGSRTSISLFHVLVTELVLTDLLGTCLISPVVLASYSRNQTLVALAPESHACTYFAFTMTFFSLATMLMLFAMALERYLSIGYPYFYRRHLSRRGGLAVLPVIYGASLLFCSLPLLNYGEYVQYCPGTWCFIRHGRTAYLQLYATMLLLLIVAVLACNISVILNLIRMHRRSRRSRCGLSGSSLRGPGSRRRGERTSMAEETDHLILLAIMTITFAICSLPFTIFAYMDETSSLKEKWDLRALRFLSVNSIIDPWVFAILRPPVLRLMRSVLCCRTSLRTQEAQQTSCSTQSSASKQTDLCGQL", "length": 362 }, "evidence": [ { "id": "HGNC:9594", "url": "https://alliancegenome.org/gene/HGNC:9594#orthology", "database": "AGR" }, { "id": "MGI:97794", "url": "https://alliancegenome.org/gene/MGI:97794#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-267", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-267#orthology", "database": "AGR" }, { "id": "Q5RI92", "url": "https://omabrowser.org/oma/group/Q5RI92/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62928-1", 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5RI92", "url": "https://www.uniprot.org/uniprotkb/Q5RI92" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "Q5RI92", "url": "https://www.uniprot.org/uniprotkb/Q5RI92" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "Q5RI92", "url": "https://www.uniprot.org/uniprotkb/Q5RI92" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "Q5RI92", "url": "https://www.uniprot.org/uniprotkb/Q5RI92" } ], "pmid": "" }, { "name": "cellular response to prostaglandin E stimulus", "id": "GO:0071380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071380", "evidence": [ { "database": "UniProtKB", "id": "Q5RI92", "url": "https://www.uniprot.org/uniprotkb/Q5RI92" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "prostaglandin E receptor activity", "id": "GO:0004957", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004957", "evidence": [ { "database": "UniProtKB", "id": "Q5RI92", "url": "https://www.uniprot.org/uniprotkb/Q5RI92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": 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"end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5RIH2-1", "uniprot_ac": "Q5RIH2", "uniprot_id": "Q5RIH2_DANRE", "mass": { "chemical_mass": 99167.0, "monoisotopic_mass": 99167.0 }, "refseq": { "ac": "XP_695978", "name": "C-1-tetrahydrofolate synthase, cytoplasmic isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695978" }, "gene_names": [ { "name": "mthfd1a", "type": "recommended", "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ] }, { "name": "mthfd1a", "type": "synonym", "evidence": [ { "id": "XP_695978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695978" } ] } ], "protein_names": [ { "name": "C-1-tetrahydrofolate synthase, cytoplasmic", "type": "recommended", "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2/entry#names_and_taxonomy" } ] }, { "name": "1.5.1.5", "type": "synonym", "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2/entry#names_and_taxonomy" } ] }, { "name": "3.5.4.9", "type": "synonym", "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2/entry#names_and_taxonomy" } ] }, { "name": "6.3.4.3", "type": "synonym", "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2/entry#names_and_taxonomy" } ] }, { "name": "C-1-tetrahydrofolate synthase, cytoplasmic isoform X1", "type": "synonym", "evidence": [ { "id": "XP_695978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695978" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_695978.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_695978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695978" } ] }, { "annotation": "Trifunctional enzyme that catalyzes the interconversion of three forms of one-carbon-substituted tetrahydrofolate: (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate, 5,10-methenyltetrahydrofolate and (6S)-10-formyltetrahydrofolate. These derivatives of tetrahydrofolate are differentially required in nucleotide and amino acid biosynthesis, (6S)-10-formyltetrahydrofolate being required for purine biosynthesis while (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate is used for serine and methionine biosynthesis for instance.", "evidence": [ { "database": "UniProtKB", "id": "Q5RIH2", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2#function" }, { "database": "UniProtKB", "id": "ARBA00059708", "url": "https://www.uniprot.org/uniprotkb/ARBA00059708#function" } ] } ], "disease": [ { "disease_id": "DOID:0080016", "recommended_name": { "id": "DOID:0080016", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080016", "name": "spina bifida", "description": "A neural tube defect that is characterized by incomplete closing of the spine and membranes around the spinal cord during early development." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0080016", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080016" } ] }, { "disease_id": "DOID:0080074", "recommended_name": { "id": "DOID:0080074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080074", "name": "neural tube defect", "description": "A physical disorder characterized by incomplete closure of the neural tube." }, "synonyms": [ { "id": "MONDO:0010525", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010525", "name": "neural tube defects, X-linked", "description": "" }, { "id": "MONDO:0010525", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010525", "name": "neural tube defects, X-linked", "description": "" }, { "id": "MONDO:0010525", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010525", "name": "X-linked anencephaly/spina bifida", "description": "" }, { "id": "MONDO:0010525", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010525", "name": "anencephaly and spina bifida X-linked", "description": "" }, { "id": "MONDO:0011120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011120", "name": "neural tube defects, folate-sensitive", "description": "" }, { "id": "MONDO:0011120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011120", "name": "neural tube defects, folate-sensitive", "description": "" }, { "id": "MONDO:0011120", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011120", "name": "NTDFS", "description": "" }, { "id": "MIM:601634", "resource": "MIM", "url": "https://www.omim.org/entry/601634", "name": "Neural tube defects, folate-sensitive", "description": "Neural tube defects, folate-sensitive" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080074" } ] }, { "disease_id": "DOID:0080633", "recommended_name": { "id": "DOID:0080633", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080633", "name": "developmental cardiac valvular defect", "description": "A physical disorder that has_material_basis_in homozygous or compound heterozygous mutation in the PLD1 gene on chromosome 3q26." }, "synonyms": [ { "id": "MONDO:0008913", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008913", "name": "cardiac valvular defect, developmental", "description": "" }, { "id": "MONDO:0008913", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008913", "name": "cardiac valvular defect, developmental", "description": "" }, { "id": "MONDO:0008913", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008913", "name": "CVDD", "description": "" }, { "id": "MIM:212093", "resource": "MIM", "url": "https://www.omim.org/entry/212093", "name": "Cardiac valvular dysplasia 1", "description": "Cardiac valvular dysplasia 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080633", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080633" } ] }, { "disease_id": "DOID:14250", "recommended_name": { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "Down syndrome", "description": "A chromosomal duplication syndrome that is characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused by trisomy of all or a critical portion of chromosome 21 and is associated with intellectual disability." }, "synonyms": [ { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "Complete trisomy 21 syndrome", "description": "" }, { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "Down's syndrome", "description": "" }, { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "Down's syndrome - trisomy 21", "description": "" }, { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "Downs syndrome", "description": "" }, { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "G Trisomy", "description": "" }, { "id": "DOID:14250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14250", "name": "trisomy 21 syndrome", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "Down syndrome", "description": "Down syndrome is a chromosomal abnormality caused by the presence of a third (partial or total) copy of the chromosome 21 genetic material and that is characterized by variable intellectual disability, muscular hypotonia, and joint laxity, often associated with a characteristic facial dysmorphism and various anomalies such as cardiac, gastrointestinal, or endocrine defects." }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "Down syndrome", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "Down syndrome, Isolated cases", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "Down's syndrome", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "leukemia, megakaryoblastic, with or without Down syndrome, somatic", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "trisomy 21 (Down syndrome)", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "complete trisomy 21 syndrome", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "trisomy 21", "description": "" }, { "id": "MONDO:0008608", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008608", "name": "trisomy 21 syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "14250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14250" } ] }, { "disease_id": "DOID:6419", "recommended_name": { "id": "DOID:6419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6419", "name": "tetralogy of Fallot", "description": "" }, "synonyms": [ { "id": "DOID:6419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6419", "name": "Ventricular septal defect with pulmonary stenosis or atresia, dextraposition of aorta, and hypertrophy of right ventricle", "description": "" }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "tetralogy of fallot", "description": "Tetralogy of Fallot is a congenital cardiac malformation that consists of an interventricular communication, also known as a ventricular septal defect, obstruction of the right ventricular outflow tract, override of the ventricular septum by the aortic root, and right ventricular hypertrophy." }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "tetralogy of fallot", "description": "" }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "ventricular septal defect with pulmonary stenosis or atresia, dextraposition of aorta, and hypertrophy of right ventricle", "description": "" }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "Fallot tetralogy", "description": "" }, { "id": "MONDO:0008542", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008542", "name": "TOF", "description": "" }, { "id": "MIM:187500", "resource": "MIM", "url": "https://www.omim.org/entry/187500", "name": "Tetralogy of Fallot", "description": "Tetralogy of Fallot" } ], "unlinked_id_list": [], "evidence": [ { "id": "6419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6419" } ] }, { "disease_id": "DOID:674", "recommended_name": { "id": "DOID:674", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:674", "name": "cleft palate", "description": "An orofacial cleft characterized by a fissure of the soft and/or hard palate, due to faulty fusion of the two plates of the skull that form the hard palate." }, "synonyms": [ { "id": "DOID:674", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:674", "name": "Palatoschisis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "674", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:674" } ] }, { "disease_id": "DOID:7693", "recommended_name": { "id": "DOID:7693", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7693", "name": "abdominal aortic aneurysm", "description": "An aortic aneurysm that is located_in the abdominal aorta." }, "synonyms": [ { "id": "DOID:7693", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7693", "name": "AORTIC ANEURYSM, FAMILIAL ABDOMINAL 1", "description": "" }, { "id": "MONDO:0012343", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012343", "name": "aortic aneurysm, familial abdominal, 2", "description": "" }, { "id": "MONDO:0012343", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012343", "name": "AAA2", "description": "" }, { "id": "MONDO:0012343", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012343", "name": "aortic aneurysm, familial abdominal 2", "description": "" }, { "id": "MONDO:0012343", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012343", "name": "aortic aneurysm, familial abdominal, 2", "description": "" }, { "id": "MONDO:0012751", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012751", "name": "aortic aneurysm, familial abdominal, 3", "description": "" }, { "id": "MONDO:0012751", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012751", "name": "AAA3", "description": "" }, { "id": "MONDO:0012751", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012751", "name": "aneurysm, familial abdominal 3", "description": "" }, { "id": "MONDO:0012751", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012751", "name": "aortic aneurysm, familial abdominal, 3", "description": "" }, { "id": "MONDO:0013716", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013716", "name": "aortic aneurysm, familial abdominal, 4", "description": "" }, { "id": "MONDO:0013716", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013716", "name": "AAA4", "description": "" }, { "id": "MONDO:0013716", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013716", "name": "aortic aneurysm, familial abdominal, 4", "description": "" }, { "id": "MONDO:0024521", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024521", "name": "aortic aneurysm, familial abdominal, 1", "description": "" }, { "id": "MONDO:0024521", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024521", "name": "AAA1", "description": "" }, { "id": "MONDO:0024521", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024521", "name": "aortic aneurysm, familial abdominal 1", "description": "" }, { "id": "MONDO:0024521", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024521", "name": "aortic aneurysm, familial abdominal, 1", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "7693", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7693" } ] }, { "disease_id": "DOID:9296", "recommended_name": { "id": "DOID:9296", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9296", "name": "cleft lip", "description": "An orofacial cleft that is characterized by a congenital defect in the upper lip where the maxillary prominence fails to merge with the merged medial nasal prominences." }, "synonyms": [ { "id": "DOID:9296", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9296", "name": "Labium leporinum", "description": "" }, { "id": "DOID:9296", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9296", "name": "cheiloschisis", "description": "" }, { "id": "DOID:9296", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9296", "name": "cleft lip, unilateral, complete", "description": "" }, { "id": "DOID:9296", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9296", "name": "complete unilateral cleft lip", "description": "" }, { "id": "DOID:9296", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9296", "name": "hare lip", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9296", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9296" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RIH2", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mthfd1a", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041001-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-127", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000018266", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000018266", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01080", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01080", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "567587", "url": "https://www.ncbi.nlm.nih.gov/gene/567587", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000559", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000559", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000672", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000672", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020630", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020630", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046346", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567587", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567587", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTNDNER", "url": "https://omabrowser.org/oma/group/CTNDNER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5RIH2", "url": "https://www.orthodb.org/?gene=Q5RIH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48099", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48099", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48099:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48099:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01268", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01268", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02882", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02882", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_695978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695978", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "20221", "url": "https://www.rhea-db.org/rhea/20221", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "23700", "url": "https://www.rhea-db.org/rhea/23700", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AB32TI49", "url": "https://www.uniprot.org/uniprotkb/A0AB32TI49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TI49-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TI49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I5D9", "url": "https://www.uniprot.org/uniprotkb/A0AC58I5D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I5D9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I5D9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RIH2", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RIH2-1", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041001-127", "url": "https://zfin.org/ZDB-GENE-041001-127", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFSVSAAVLRRGVLRYRWDRCCALATVVSGNKTSQQVKQRLKEEVEQMKSQFPGFRPGLVVLQVGDREDSNLYISMKLKAAAEIGINANHIRLPETATENEVLRNIVAVNENPAFHGLIVQLPLDSINPINTEKITNAVAPEKDVDGLTSINAGKLSRGDLGDCFIPCTPNGCMELISQTGVSVMGKNAVVIGRSKIVGAPMHDLLLWSHATVTTCHSKTPDLAEQVGKADILVVGAGRAEMVKGEWVKEGAVVIDCGINHIPDESKASGKRVVGDVHYPSAKQRAGFITPVPGGVGPMTVAMLMKNTVESAKRFLQTHTPGKWNLVYTKKRPHEPQPSDAAISSSCESKPVVQLARELGLFSDEVESYGRSRAKIRLDALKRMEKQPNGKYVVVTGVTSSPLGEGKRTTALGLAQALGAHLNTNAFACVQKSSLETCFGARGPAVGGGYSQIIPLEEVSLQPSGQNELVSAAGRLVMDTVKAYAHYETKLSEKALFDLLVPLREGQRCVSLAQLNRLKKLAIEKSDPLTLTEREIRRFIRLDIDTDSATDSFSLENEMMAVLSLSSSEEEMQHRLANIIVATNKSGDPITTEDLNVSGPLAMLLKEALKPVLMQTVEGTPVFLHTSPLVNVAQGGPSILADKMALKIVGSEGFVVTESGHGADVGLEKFFNIKCLYSGLQPDVLVMVATIRTLKMQGGAPPIQAGLPLPKEYLQENLKQLERGCCHMRRQVEKAQAFGLPVIVAVNKFSSDTDAELELVCGQARQAGAFDAVQCSSWSEGGAGALALAETVQRAAKLPACFKFLYDLQTPASDKLRTVAQKMYGLKDVKLSPKAKEKLALYTKQGFENLPVCIAKTPLSLSNDPMMKGSSTDFMLPITDIKANAGAGFLCCLTGSTNAEMDDPMWPCFHGNNLYSDSK", "length": 919, "header": "tr|Q5RIH2-1|Q5RIH2_DANRE Isoform 1 of C-1-tetrahydrofolate synthase, cytoplasmic OS=Danio rerio OX=7955 GN=mthfd1a PE=3 SV=3 CANONICAL=Q5RIH2-1" }, "isoforms": [ { "isoform_ac": "A0AB32TI49-1", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2/entry#A0AB32TI49-1", "sequence": { "sequence": "MFSVSAAVLRRGVLRYRWDRCCALATVVSGNKTSQQVKQRLKEEVEQMKSQFPGFRPGLVVLQVGDREDSNLYISMKLKAAAEIGINANHIRLPETATENEVLRNIVAVNENPAFHGLIVQLPLDSINPINTEKITNAVAPEKDVDGLTSINAGKLSRGDLGDCFIPCTPNGCMELISQTGVSVMGKNAVVIGRSKIVGAPMHDLLLWSHATVTTCHSKTPDLAEQVGKADILVVGAGRAEMVKGEWVKEGAVVIDCGINHIPDESKASGKRVVGDVHYPSAKQRAGFITPVPGGVGPMTVAMLMKNTVESAKRFLQTHTPGKWNLVYTKKRPHEPQPSDAAISSSCESKPVVQLARELGLFSDEVESYGRSRAKIRLDALKRMEKQPNGKYVVVTGVTSSPLGEGKRTTALGLAQALGAHLNTNAFACVQKSSLETCFGARGPAVGGGYSQIIPLEEVSLQPSGQNELVSAAGRLVMDTVKAYAHYETKLSEKALFDLLVPLREGQRCVSLAQLNRLKKLAIEKSDPLTLTEREIRRFIRLDIDTDSATDSFSLENEMMAVLSLSSSEEEMQHRLANIIVATNKSGDPITTEDLNVSGPLAMLLKEALKPVLMQTVEGTPVFLHTSPLVNVAQGGPSILADKMALKIVGSEGFVVTESGHGADVGLEKFFNIKCLYSGLQPDVLVMVATIRTLKMQGGAPPIQAGLPLPKEYLQENLKQLERGCCHMRRQVEKAQAFGLPVIVAVNKFSSDTDAELELVCGQARQAGAFDAVQCSSWSEGGAGALALAETVQRAAKLPACFKFLYDLQTPASDKLRTVAQKMYGLKDVKLSPKAKEKLALYTKQEL", "length": 847, "header": "tr|A0AB32TI49-1|A0AB32TI49_DANRE Computationally mapped isoform of C-1-tetrahydrofolate synthase, cytoplasmic OS=Danio rerio OX=7955 GN=mthfd1a PE=3 SV=1 CANONICAL=Q5RIH2-1" }, "locus": {} }, { "isoform_ac": "A0AC58I5D9-1", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2/entry#A0AC58I5D9-1", "sequence": { "sequence": "MFSVSAAVLRRGVLRYRWDRCCALATVVSGNKTSQQVKQRLKEEVEQMKSQFPGFRPGLVVLQIGINANHIRLPETATENEVLRNIVAVNENPAFHGLIVQLPLDSINPINTEKITNAVAPEKDVDGLTSINAGKLSRGDLGDCFIPCTPNGCMELISQTGVSVMGKNAVVIGRSKIVGAPMHDLLLWSHATVTTCHSKTPDLAEQVGKADILVVGAGRAEMVKGEWVKEGAVVIDCGINHIPDESKASGKRVVGDVHYPSAKQRAGFITPVPGGVGPMTVAMLMKNTVESAKRFLQTHTPGKWNLVYTKKRPHEPQPSDAAISSSCESKPVVQLARELGLFSDEVESYGRSRAKIRLDALKRMEKQPNGKYVVVTGVTSSPLGEGKRTTALGLAQALGAHLNTNAFACVQKSSLETCFGARGPAVGGGYSQIIPLEEVSLQPSGQNELVSAAGRLVMDTVKAYAHYETKLSEKALFDLLVPLREGQRCVSLAQLNRLKKLAIEKSDPLTLTEREIRRFIRLDIDTDSATDSFSLENEMMAVLSLSSSEEEMQHRLANIIVATNKSGDPITTEDLNVSGPLAMLLKEALKPVLMQTVEGTPVFLHTSPLVNVAQGGPSILADKMALKIVGSEGFVVTESGHGADVGLEKFFNIKCLYSGLQPDVLVMVATIRTLKMQGGAPPIQAGLPLPKEYLQENLKQLERGCCHMRRQVEKAQAFGLPVIVAVNKFSSDTDAELELVCGQARQAGAFDAVQCSSWSEGGAGALALAETVQRAAKLPACFKFLYDLQTPASDKLRTVAQKMYGLKDVKLSPKAKEKLALYTKQGFENLPVCIAKTPLSLSNDPMMKGSSTDFMLPITDIKANAGAGFLCCLTGSTNAEMDDPMWPCFHGNNLYSDSK", "length": 899, "header": "tr|A0AC58I5D9-1|A0AC58I5D9_DANRE Computationally mapped isoform of C-1-tetrahydrofolate synthase, cytoplasmic OS=Danio rerio OX=7955 GN=mthfd1a PE=3 SV=1 CANONICAL=Q5RIH2-1" }, "locus": {} }, { "isoform_ac": "Q5RIH2-1", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2/entry#Q5RIH2-1", "sequence": { "sequence": "MFSVSAAVLRRGVLRYRWDRCCALATVVSGNKTSQQVKQRLKEEVEQMKSQFPGFRPGLVVLQVGDREDSNLYISMKLKAAAEIGINANHIRLPETATENEVLRNIVAVNENPAFHGLIVQLPLDSINPINTEKITNAVAPEKDVDGLTSINAGKLSRGDLGDCFIPCTPNGCMELISQTGVSVMGKNAVVIGRSKIVGAPMHDLLLWSHATVTTCHSKTPDLAEQVGKADILVVGAGRAEMVKGEWVKEGAVVIDCGINHIPDESKASGKRVVGDVHYPSAKQRAGFITPVPGGVGPMTVAMLMKNTVESAKRFLQTHTPGKWNLVYTKKRPHEPQPSDAAISSSCESKPVVQLARELGLFSDEVESYGRSRAKIRLDALKRMEKQPNGKYVVVTGVTSSPLGEGKRTTALGLAQALGAHLNTNAFACVQKSSLETCFGARGPAVGGGYSQIIPLEEVSLQPSGQNELVSAAGRLVMDTVKAYAHYETKLSEKALFDLLVPLREGQRCVSLAQLNRLKKLAIEKSDPLTLTEREIRRFIRLDIDTDSATDSFSLENEMMAVLSLSSSEEEMQHRLANIIVATNKSGDPITTEDLNVSGPLAMLLKEALKPVLMQTVEGTPVFLHTSPLVNVAQGGPSILADKMALKIVGSEGFVVTESGHGADVGLEKFFNIKCLYSGLQPDVLVMVATIRTLKMQGGAPPIQAGLPLPKEYLQENLKQLERGCCHMRRQVEKAQAFGLPVIVAVNKFSSDTDAELELVCGQARQAGAFDAVQCSSWSEGGAGALALAETVQRAAKLPACFKFLYDLQTPASDKLRTVAQKMYGLKDVKLSPKAKEKLALYTKQGFENLPVCIAKTPLSLSNDPMMKGSSTDFMLPITDIKANAGAGFLCCLTGSTNAEMDDPMWPCFHGNNLYSDSK", "length": 919, "header": "tr|Q5RIH2-1|Q5RIH2_DANRE Isoform 1 of C-1-tetrahydrofolate synthase, cytoplasmic OS=Danio rerio OX=7955 GN=mthfd1a PE=3 SV=3 CANONICAL=Q5RIH2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "dre:567587", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567587", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QQ79-1", "protein_name": "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "gene_name": "mthfd1l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMRLSVAFRHARRSHSTIQRSRTCVKFLSRENRHTPDISAVSFLRAREASSTSGTTETAASLQSHARKYEGPPYERAVGDIVQRCREELKSIGENNPGLKPTLAIIQAGEDDGLLEMNKKMAGKIGLNVMQICLPHRCTEEEVIEEVLRLNKDSRVHGIFLHLPQTFLSKSVRNAIKPQKDVDGVCDLNVGRVVLGDKTDGFTSPVAGAVLELLAKHDAPLVGKMAVLVGLEGPLKVALQCLLQNNGMILQTCRWSSTNLQKQIMDSDVVITLNTNQNHIPSTWLRPGVAAINLGSALLEEHPDSWEATVEAQSAAGLGPLTAAFRMQHVVRSSRRWIQEQQYQPWNIRPLKLHPLSPVPSDIEISRAQTPKPISQLAQEIGLLPEELEAYGNTKAKVHLSLLNRLQHQPDGRYVLVAGITPTPLGEGKSTVTIGLAQALTAHLKLNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARILHEATQSDKALYSRLVPSVNGVRRFSPIQLARLQRLGINKSNPTDLTPQEVSAFVRLDLDPEKVTWQRVVDTNDRFLRKITIGQANTEKGHARQTQFDIAVASEIMAILALTDGLADMRARLGRMVVGSSRNGQAITADDLGVTGALAVLMKDAIKPTLMQTLEGTPVFVHAGPFANIAHGNSSVLADKLALKLVGEEGYVVTEAGFGADIGMEKFFNIKCRTSGLRPNVVVLVATIRALKMHGGGPNVTAGAPLPKEYIEENLQLVADGCSNLKKQIQIAHLFGVPVVVALNAFKTDTQAEIDLVCRIAKASGASAAVPCHHWSRGGRGSLELAHAVKEVAAQGSRFQFLYNLQDPIVEKIRTIAQKVYGAEDIELSSEAQAKIDYYNQQGFGALPICMAKTHLSLSHMPEKKGVPTNFILPIRDVRASIGAGFIYPLVGTMSTMPGLPTRPCFYDIDLDPVTEEIKGLF", "length": 978 }, "evidence": [ { "id": "FB:FBgn0020385", "url": "https://alliancegenome.org/gene/FB:FBgn0020385#orthology", "database": "AGR" }, { "id": "SGD:S000000288", "url": "https://alliancegenome.org/gene/SGD:S000000288#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O96553-1", "protein_name": "C-1-tetrahydrofolate synthase, cytoplasmic", "gene_name": "pug", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSAQYQRFLKVLEKWPAEKSKVGSGEWTAEPAIKMSGAKIISGTAVAKSIREELRNEVTAMSKQLADFVPGLRIVQVGGREDSNVYIRMKIKAATEIGIDAAHVQLPRSITEVELLDKINDLNEDPRVHGIIVQMPLDCDTPIDSHRITDAVSPEKDVDGLHTVNEGRLAIGDLGGFLPCTPWGCLELIRRSGVEIAGARAVVLGRSKIVGTPAAELLKWANATVTVCHSKTRNLEEITRSADILVVGIGVAEMVKGSWIKPGAVVIDCGINVKPDASKASGSKLVGDVDYAEALQVAGHLTPVPGGVGPMTVAMLMKNTVRSAARFLERLAKSQWALQTLPLKPQRPVPSDIVIARAQKPKDIAVLAKEIGLEAREVSLYGNKKAKISLSVLERLKDKEVGHYVVVAGMTPTPLGEGKTTTLMGLVQALGAHKLRNTMAALRQPSQGPTFGIKGGAAGGGYAQVIPMEEFNLHLTGDIHAVSAANNLLAAQLDTRIFHENTQKDKALYDRLVPAIKGQRKFSPIQLRRLQKLGITKTDPDTLTADEYGPFARLDIDPDTIMWERVVDINDRYLRTITVGQSPTEKGISRETRFSISVASEIMAVLALSRSLEDMKQRLADMVVAFDKRGKPVTADDLGVTGALAVLLKDALEPNLMQSLEGTPVLVHAGPFANIAHGCNSIIADEVGLKLVGKNGFVCTEAGFGSDIGMEKFCNIKCRTSGRKPNAMVLVATVRAIKMHGGGAPVTPGAPLNKQYTEENLELVQKGLPNLLQHIENGKAFGMPVVVSLNAHSADTPAEHELVKKAALEAGAFAAVVSTHWADGGAGAVQLADAVIKACEQGNQFRLLYDLELPLVDKMNKIATTMYGAGKVVLSPAAEEKVKRLTDAGFGNLPICMSKVSGSFTGDAKIKGAPKGFTLDVEDVYVSAGAGFVVAMCGEVTKMPGLPTRPAIYDIDLNTETGEIEGLF", "length": 968 }, "evidence": [ { "id": "MGI:1342005", "url": "https://alliancegenome.org/gene/MGI:1342005#orthology", "database": "AGR" }, { "id": "HGNC:7432", "url": "https://alliancegenome.org/gene/HGNC:7432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-127#orthology", "database": "AGR" }, { "id": "FB:FBgn0020385", "url": "https://alliancegenome.org/gene/FB:FBgn0020385#orthology", "database": "AGR" }, { "id": "RGD:708531", "url": "https://alliancegenome.org/gene/RGD:708531#orthology", "database": "AGR" }, { "id": "SGD:S000000288", "url": "https://alliancegenome.org/gene/SGD:S000000288#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P07245-1", "protein_name": "C-1-tetrahydrofolate synthase, cytoplasmic", "gene_name": "ADE3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAGQVLDGKACAQQFRSNIANEIKSIQGHVPGFAPNLAIIQVGNRPDSATYVRMKRKAAEEAGIVANFIHLDESATEFEVLRYVDQLNEDPHTHGIIVQLPLPAHLDEDRITSRVLAEKDVDGFGPTNIGELNKKNGHPFFLPCTPKGIIELLHKANVTIEGSRSVVIGRSDIVGSPVAELLKSLNSTVTITHSKTRDIASYLHDADIVVVAIGQPEFVKGEWFKPRDGTSSDKKTVVIDVGTNYVADPSKKSGFKCVGDVEFNEAIKYVHLITPVPGGVGPMTVAMLMQNTLIAAKRQMEESSKPLQIPPLPLKLLTPVPSDIDISRAQQPKLINQLAQELGIYSHELELYGHYKAKISPKVIERLQTRQNGKYILVSGITPTPLGEGKSTTTMGLVQALTAHLGKPAIANVRQPSLGPTLGVKGGAAGGGYSQVIPMDEFNLHLTGDIHAIGAANNLLAAAIDTRMFHETTQKNDATFYNRLVPRKNGKRKFTPSMQRRLNRLGIQKTNPDDLTPEEINKFARLNIDPDTITIKRVVDINDRMLRQITIGQAPTEKNHTRVTGFDITVASELMAILALSKDLRDMKERIGRVVVAADVNRSPVTVEDVGCTGALTALLRDAIKPNLMQTLEGTPVLVHAGPFANISIGASSVIADRVALKLVGTEPEAKTEAGYVVTEAGFDFTMGGERFFNIKCRSSGLTPNAVVLVATVRALKSHGGAPDVKPGQPLPSAYTEENIEFVEKGAANMCKQIANIKQFGVPVVVAINKFETDTEGEIAAIRKAALEAGAFEAVTSNHWAEGGKGAIDLAKAVIEASNQPVDFHFLYDVNSSVEDKLTTIVQKMYGGAAIDILPEAQRKIDMYKEQGFGNLPICIAKTQYSLSHDATLKGVPTGFTFPIRDVRLSNGAGYLYALAAEIQTIPGLATYAGYMAVEVDDDGEIDGLF", "length": 946 }, "evidence": [ { "id": "MGI:1342005", "url": "https://alliancegenome.org/gene/MGI:1342005#orthology", "database": "AGR" }, { "id": "HGNC:7432", "url": "https://alliancegenome.org/gene/HGNC:7432#orthology", "database": "AGR" }, { "id": "FB:FBgn0020385", "url": "https://alliancegenome.org/gene/FB:FBgn0020385#orthology", "database": "AGR" }, { "id": "RGD:708531", "url": "https://alliancegenome.org/gene/RGD:708531#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P09440-1", "protein_name": "C-1-tetrahydrofolate synthase, mitochondrial", "gene_name": "MIS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLSRLSLLSNSRAFQQARWRIYRLKVSPTVHASQYHILSGRKLAQSIREKANDEIQAIKLKHPNFKPTLKIIQVGARPDSSTYVRMKLKASKDSNVDCIIEKLPAEITEVELLKKISDINDDDSIHGLLIQLPLPRHLDETTITNAVDFKKDVDGFHRYNAGELAKKGGKPYFIPCTPYGCMKLLEEAHVKLDGKNAVVLGRSSIVGNPIASLLKNANATVTVCHSHTRNIAEVVSQADIVIAACGIPQYVKSDWIKEGAVVIDVGINYVPDISKKSGQKLVGDVDFDSVKEKTSYITPVPGGVGPMTVAMLVSNVLLAAKRQFVESEKLPVIKPLPLHLESPVPSDIDISRAQSPKHIKQVAEELGIHSHELELYGHYKAKISPNIFKRLESRENGKYVLVAGITPTPLGEGKSTTTMGLVQALSAHLGKPSIANVRQPSLGPTLGVKGGAAGGGYAQVIPMDEFNLHLTGDIHAISAANNLLAAAIDTRMFHEATQKNDSTFYKRLVPRKKGIRKFTPSMQRRLKRLDIEKEDPDALTPEEVKRFARLNINPDTITIRRVVDINDRMLRQITIGEAATEKGFTRTTGFDITVASELMAILALSKSLHEMKERIGRMVIGADYDNKPVTVEDIGCTGALTALLRDAIKPNLMQTLEGTPVMVHAGPFANISIGASSVIADLMALKLVGSEKNPLNDKNIHEPGYVVTEAGFDFAMGGERFFDIKCRSSGLVPDAVVLVATVRALKSHGGAPNVKPGQSLPKEYTEENIDFVAKGVSNLVKQIENIKTFGIPVVVAINRFETDSQAEIEVIKKAALNAGASHAVTSNHWMEGGKGAVELAHAVVDATKEPKNFNFLYDVNSSIEDKLTSIVQKMYGGAKIEVSPEAQKKIDTYKKQGFGNLPICIAKTQYSLSHDPSLKGVPRGFTFPIRDVRASIGAGYLYALAAEIQTIPGLSTYAGYMAVEVDDDGEIEGLF", "length": 975 }, "evidence": [ { "id": "MGI:1342005", "url": "https://alliancegenome.org/gene/MGI:1342005#orthology", "database": "AGR" }, { "id": "HGNC:7432", "url": "https://alliancegenome.org/gene/HGNC:7432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-127#orthology", "database": "AGR" }, { "id": "FB:FBgn0020385", "url": "https://alliancegenome.org/gene/FB:FBgn0020385#orthology", "database": "AGR" }, { "id": "RGD:708531", "url": "https://alliancegenome.org/gene/RGD:708531#orthology", "database": "AGR" }, { "id": "SGD:S000000288", "url": "https://alliancegenome.org/gene/SGD:S000000288#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P11586-1", "protein_name": "C-1-tetrahydrofolate synthase, cytoplasmic", "gene_name": "MTHFD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPAEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEIGIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKDVDGLTSINAGKLARGDLNDCFIPCTPKGCLELIKETGVPIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTAHLDEEVNKGDILVVATGQPEMVKGEWIKPGAIVIDCGINYVPDDKKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESAKRFLEKFKPGKWMIQYNNLNLKTPVPSDIDISRSCKPKPIGKLAREIGLLSEEVELYGETKAKVLLSALERLKHRPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLYQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLVPSVNGVRRFSDIQIRRLKRLGIEKTDPTTLTDEEINRFARLDIDPETITWQRVLDTNDRFLRKITIGQAPTEKGHTRTAQFDISVASEIMAVLALTTSLEDMRERLGKMVVASSKKGEPVSAEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVGPEGFVVTEAGFGADIGMEKFFNIKCRYSGLCPHVVVLVATVRALKMHGGGPTVTAGLPLPKAYIQENLELVEKGFSNLKKQIENARMFGIPVVVAVNAFKTDTESELDLISRLSREHGAFDAVKCTHWAEGGKGALALAQAVQRAAQAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIELLPEAQHKAEVYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFILPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF", "length": 935 }, "evidence": [ { "id": "MGI:1342005", "url": "https://alliancegenome.org/gene/MGI:1342005#orthology", "database": "AGR" }, { "id": "HGNC:7432", "url": "https://alliancegenome.org/gene/HGNC:7432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-127#orthology", "database": "AGR" }, { "id": "FB:FBgn0020385", "url": "https://alliancegenome.org/gene/FB:FBgn0020385#orthology", "database": "AGR" }, { "id": "RGD:708531", "url": "https://alliancegenome.org/gene/RGD:708531#orthology", "database": "AGR" }, { "id": "SGD:S000000288", "url": "https://alliancegenome.org/gene/SGD:S000000288#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P27653-1", "protein_name": "C-1-tetrahydrofolate synthase, cytoplasmic", "gene_name": "Mthfd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPAGILNGKVVSAQIRNRLKTQVTQMQEQVPGFTPGLAILQVGDRDDSNLYINVKLKAAQEIGIKATHIKLPRTSTESEVLKYVISLNEDATVHGFIVQLPLDSENSINTEAVINAIAPEKDVDGLTSINAGKLARGDLKDCFIPCTPKGCLELIKETGVQIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTADLDKEVNKGDILVVATGQPEMVKGEWIKPGAVVIDCGINYVPDDTKPNGRKVVGDVAYDEAKEKASFITPVPGGVGPMTVAMLMQSTVESAQRFLKKFKPGKWTIQYNKLNLKTPVPSDIAISRSCKPKLIGNLAREIGLLTEEVELYGETKAKVLLSALDRLKHQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLHQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLVPSVNGVRKFSDIQIRRLRRLGIEKTDPAALTDDEINRFARLDIDPETITWQRVLDTNDRFLRKITIGQAPTEKGHTRTAQFDISVASEIMAVLALTSSLEDMRARLGKMVVASSKKGEPISCEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVGPEGFVVTEAGFGADIGMEKFFNIKCRYSGLQPHVVVLVATVRALKMHGGGPTVTAGLPLPKAYTEEDLDLVEKGFSNLRKQIENARMFGVPVVVAMNAFKTDTDTELDLIGRLSREHGAFDAVKCTHWAEGGQGALALAQAVQRASQAPSSFQLLYDLKLSVEDKIRIIAQKIYGADDIELLPEAQNKAEIYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFVLPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF", "length": 935 }, "evidence": [ { "id": "MGI:1342005", "url": "https://alliancegenome.org/gene/MGI:1342005#orthology", "database": "AGR" }, { "id": "HGNC:7432", "url": "https://alliancegenome.org/gene/HGNC:7432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-127#orthology", "database": "AGR" }, { "id": "FB:FBgn0020385", "url": "https://alliancegenome.org/gene/FB:FBgn0020385#orthology", "database": "AGR" }, { "id": "RGD:708531", "url": "https://alliancegenome.org/gene/RGD:708531#orthology", "database": "AGR" }, { "id": "SGD:S000000288", "url": "https://alliancegenome.org/gene/SGD:S000000288#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3V3R1-1", "protein_name": "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "gene_name": "Mthfd1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRLPLLLRQLGRQQLPSGPACRLRELCRSGSRSSSSGGGDPEGLRGRRLQDGQTFSSHGPGNPEAPGMDSIVRDVIHNSKEVLSLLQEKNPAFKPVLVVIQAGDDNLMKDMNQNLAKEAGLDITHICLPPDSGEDEIIDEILKINEDPRVHGLTLQISEDSLSNKVLNALKPEKDVDGVTDINLGKLVRGDAPECFVSPLAKAAVELVEKSGITLDGKKVLVVGAHGPLEAALQWLFQRKGSMTMSCPWATPQLPDKLREADIVVLGSPKPEEIPAVWIPSGTTILNCFHDFLSGKLSGGSPGVPVDKLIAEESVSLLAAALRIQNMVSSGRRWLREQQHRRWRLHCLKLQPLSPVPSDIEISRGQTPKAVDVLAKEIGLLADEIEIYGKSKAKVQLSLLERLKDQTDGKYVLVAGITPTPLGEGKSTVTIGLVQALTAHLKVNSFACLRQPSQGPTFGVKGGAAGGGYAQVIPMEEFNLHLTGDIHAITAANNLLAAAIDTRILHESTQTDKALYNRLVPLVNGVREFSEIQLSRLKKLGIHKTDPSTLTEEEVRKFARLNIDPATITWQRVLDTNDRFLRKITIGQGSTEKGYSRQAQFDIAVASEIMAVLALTDSLTDMKERLGRMVVASDKDGQPVTAEDLGVTGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSVLADKIALKLVGEEGFVVTEAGFGADIGMEKFFNIKCRASGLVPNVVVLVATVRALKMHGGGPSVTAGVPLKKEYTEENIQLVADGCCNLQKQIQIAQLFGVPVVVALNVFKTDTRAEIDLVCELAKRAGAFDAVPCYHWSAGGKGSVDLARAVREAANKRSRFQFLYDVQLPIVEKIRVIAQTVYGAKDIELSPEAQSKIDRYTQQGFGNLPICMAKTHLSLSHEPDKKGVPRDFTLPISDVRASIGAGFIYPLVGTMSTMPGLPTRPCFYDIDLDTETEQVKGLF", "length": 977 }, "evidence": [ { "id": "FB:FBgn0020385", "url": "https://alliancegenome.org/gene/FB:FBgn0020385#orthology", "database": "AGR" }, { "id": "SGD:S000000288", "url": "https://alliancegenome.org/gene/SGD:S000000288#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UB35-1", "protein_name": "Monofunctional C1-tetrahydrofolate synthase, mitochondrial", "gene_name": "MTHFD1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"evidence": [ { "id": "FB:FBgn0020385", "url": "https://alliancegenome.org/gene/FB:FBgn0020385#orthology", "database": "AGR" }, { "id": "SGD:S000000288", "url": "https://alliancegenome.org/gene/SGD:S000000288#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q922D8-1", "protein_name": "C-1-tetrahydrofolate synthase, cytoplasmic", "gene_name": "Mthfd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPAGILNGKLVSAQIRDRLKNQVTRMQEQVPGFTPGLAILQVGDRDDSNLYINVKLKAAEEIGIKATHIKLPRTSTESEVLKYVISLNEDASVHGFIVQLPLDSENSINTEAVINAIAPEKDVDGLTSVSAGKLARGDLNDCFIPCTPKGCLELIKEAGVQIAGRHAVVVGRSKIVGAPMHDLLLWNNATVTTCHSKTANLDKEVNKGDILVVATGQPEMVKGEWIKPGAVVIDCGINYVPDDTKPNGRKVVGDVAYDEAKERASFITPVPGGVGPMTVAMLMQSTVESAQRFLQKFKPGKWTIQYNKLNLKTPVPSDIAISRSCKPKLIGNLAREIGLLTEEVELYGETKAKVLLSALDRLKHQPDGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLRQNVFACVRQPSQGPTFGIKGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHELTQTDKALFNRLVPSVNGIRKFSDIQIRRLRRLGIEKTDPTTLTDDEINRFARLDIDPETITWQRVLDTNDRFLRKITIGQSPTEKGHTRTAQFDISVASEIMAVLALTSSLEDMRERLGRMVVASSKKGEPISCEDLGVSGALTVLMKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLVGPEGFVVTEAGFGADIGMEKFFNIKCRYSGLQPHVVVLVATVRALKMHGGGPTVTAGLPLPKAYTEEDLDLVEKGFSNLRKQIENARMFGVPVVVAVNVFKTDTDAELDLVSRLSREHGAFDAVKCTHWAEGGQGALALAQAVQRASQAPSSFQLLYDLKLSIEDKIRIIAQRIYGADDIELLPEAQNKAEIYTKQGFGNLPICMAKTHLSLSHNPEQKGVPTGFVLPIRDIRASVGAGFLYPLVGTMSTMPGLPTRPCFYDIDLDPETEQVNGLF", "length": 935 }, "evidence": [ { "id": "MGI:1342005", "url": "https://alliancegenome.org/gene/MGI:1342005#orthology", "database": "AGR" }, { "id": "HGNC:7432", "url": "https://alliancegenome.org/gene/HGNC:7432#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-127#orthology", "database": "AGR" }, { "id": "FB:FBgn0020385", "url": "https://alliancegenome.org/gene/FB:FBgn0020385#orthology", "database": "AGR" }, { "id": "RGD:708531", "url": "https://alliancegenome.org/gene/RGD:708531#orthology", "database": "AGR" }, { "id": "SGD:S000000288", "url": "https://alliancegenome.org/gene/SGD:S000000288#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "Q5RIH2", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ], "pmid": "" }, { "name": "formate-tetrahydrofolate ligase activity", "id": "GO:0004329", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004329", "evidence": [ { "database": "UniProtKB", "id": "Q5RIH2", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ], "pmid": "" }, { "name": "methenyltetrahydrofolate cyclohydrolase activity", "id": "GO:0004477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004477", "evidence": [ { "database": "UniProtKB", "id": "Q5RIH2", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ], "pmid": "" }, { "name": "methylenetetrahydrofolate dehydrogenase (NADP+) activity", "id": "GO:0004488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004488", "evidence": [ { "database": "UniProtKB", "id": "Q5RIH2", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "Q5RIH2", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "tetrahydrofolate interconversion", "id": "GO:0035999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035999", "evidence": [ { "database": "UniProtKB", "id": "Q5RIH2", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ], "pmid": "" }, { "name": "one-carbon metabolic process", "id": "GO:0006730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006730", "evidence": [ { "database": "UniProtKB", "id": "Q5RIH2", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ], "pmid": "" }, { "name": "tetrahydrofolate metabolic process", "id": "GO:0046653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046653", "evidence": [ { "database": "UniProtKB", "id": "Q5RIH2", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "20221", "name": "", "equation": "(6S)-5,6,7,8-tetrahydrofolate + formate + ATP = (6R)-10-formyltetrahydrofolate + ADP + phosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5RIH2-1", "F1QQ79-1" ], "evidence": [ { "id": "20221", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20221" } ] }, { "id": "23700", "name": "", "equation": "(6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8M2BEG5-1", "Q5RIH2-1" ], "evidence": [ { "id": "23700", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23700" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8M2BEG5", "gene_name": "mthfd2l", "activity": [ { "ec_number": "3.5.4.9", "activity": "(6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H(+).", "evidence": [ { "id": "A0A8M2BEG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BEG5" } ] }, { "ec_number": "3.5.4.9", "activity": "", "evidence": [ { "id": "A0A8M2BEG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BEG5" } ] } ] }, { "uniprot_ac": "F1QQ79", "gene_name": "mthfd1l", "activity": [ { "ec_number": "6.3.4.3", "activity": "(6S)-5,6,7,8-tetrahydrofolate + formate + ATP = (6R)-10-formyltetrahydrofolate + ADP + phosphate.", "evidence": [ { "id": "F1QQ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QQ79" } ] }, { "ec_number": "6.3.4.3", "activity": "", "evidence": [ { "id": "F1QQ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QQ79" } ] } ] }, { "uniprot_ac": "Q5RIH2", "gene_name": "mthfd1a", "activity": [ { "ec_number": "6.3.4.3", "activity": "(6S)-5,6,7,8-tetrahydrofolate + formate + ATP = (6R)-10-formyltetrahydrofolate + ADP + phosphate.", "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ] }, { "ec_number": "1.5.1.5", "activity": "(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methenyltetrahydrofolate + NADPH.", "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ] }, { "ec_number": "3.5.4.9", "activity": "(6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H(+).", "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ] }, { "ec_number": "6.3.4.3", "activity": "", "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ] }, { "ec_number": "3.5.4.9", "activity": "", "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ] }, { "ec_number": "1.5.1.5", "activity": "", "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" }, { "id": "PF02882", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02882" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetrahydrofolate dehydrogenase/cyclohydrolase NAD(P)-binding", "eco_id": "ECO_0000259", "start_pos": 167, "end_pos": 314, "start_aa": "Pro", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5RIH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIH2" }, { "id": "PF00763", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00763" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetrahydrofolate dehydrogenase/cyclohydrolase catalytic", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 146, "start_aa": "Ser", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.3.4.3", "ec_name": "(6S)-5,6,7,8-tetrahydrofolate + formate + ATP = (6R)-10-formyltetrahydrofolate + ADP + phosphate.", "evidence": [ { "id": "6.3.4.3", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.3.4.3" }, { "id": "6.3.4.3", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.3.4.3" } ] }, { "ec_number": "1.5.1.5", "ec_name": "(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methenyltetrahydrofolate + NADPH.", "evidence": [ { "id": "1.5.1.5", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.1.5" }, { "id": "1.5.1.5", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.5.1.5" } ] }, { "ec_number": "3.5.4.9", "ec_name": "(6R)-5,10-methenyltetrahydrofolate + H2O = (6R)-10-formyltetrahydrofolate + H(+).", "evidence": [ { "id": "3.5.4.9", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.5.4.9" }, { "id": "3.5.4.9", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.5.4.9" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 31, "end_pos": 33 }, { "start_pos": 584, "end_pos": 586 }, { "start_pos": 596, "end_pos": 598 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q5RII3-1", "uniprot_ac": "Q5RII3", "uniprot_id": "GINM1_DANRE", "mass": { "chemical_mass": 39274.0, "monoisotopic_mass": 39274.0 }, "refseq": { "ac": "NP_001073305", "name": "glycoprotein integral membrane protein 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073305" }, "gene_names": [ { "name": "ginm1", "type": "recommended", "evidence": [ { "id": "Q5RII3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RII3" } ] }, { "name": "ginm1", "type": "synonym", "evidence": [ { "id": "NP_001073305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073305" } ] }, { "name": "si:ch211-87e4.1", "type": "synonym", "evidence": [ { "id": "Q5RII3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RII3" } ] }, { "name": "si:dkey-15j16.2", "type": "synonym", "evidence": [ { "id": "NP_001073305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073305" }, { "id": "Q5RII3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RII3" } ] } ], "protein_names": [ { "name": "Glycoprotein integral membrane protein 1", "type": "recommended", "evidence": [ { "id": "Q5RII3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RII3/entry#names_and_taxonomy" } ] }, { "name": "glycoprotein integral membrane protein 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001073305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073305" } ] }, { "name": "glycoprotein integral membrane protein 1", "type": "synonym", "evidence": [ { "id": "NP_001073305", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073305" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC142753.1, SRR32588728.3243506.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. On Dec 21, 2006 this sequence version replaced XP_683483.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001073305", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073305" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RII3", "url": "https://www.uniprot.org/uniprotkb/Q5RII3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ginm1", "url": "https://www.uniprot.org/uniprotkb/Q5RII3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-5900", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5900", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5RII3", "url": "https://alphafold.ebi.ac.uk/entry/Q5RII3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000021975", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000021975", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "555775", "url": "https://www.ncbi.nlm.nih.gov/gene/555775", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR042319", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042319", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:555775", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555775", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FNLMEVI", "url": "https://omabrowser.org/oma/group/FNLMEVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5RII3", "url": "https://www.orthodb.org/?gene=Q5RII3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28549", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28549", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28549:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28549:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28137", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28137", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5RII3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5RII3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001073305", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073305", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5RII3", "url": "https://www.uniprot.org/uniprotkb/Q5RII3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RII3-1", "url": "https://www.uniprot.org/uniprotkb/Q5RII3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-5900", "url": "https://zfin.org/ZDB-GENE-030131-5900", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASRCKIHLTVAYLLILCILASAQSKQMTTETVVLNVTALSEINQTKYNVQINLNIGLLDNDIFINGAPLKPSGVTRMTCPALLLDGYNVSSGNSVDGLVSCELRLMVNQSYVQSDAAEQLLFLVLSQEIIQLADEKVQQPEISEVEIMWNQSSEQMTQVTSIYPSARSKLSIIPRENDVLVTDASVQSAVEDQVRNTTSHYLLKNSETTQEEIAAPGKLPETPLRMDPETLYESREEEERRSDSLLLEPPLSGSMSSYSVACQWVEKLRDKLRRFLSDSVPLFFLVMWVVVVGVAGSAVVIKILDLIFPSCEHRGFFHLNPETLMPDDEKVSLIDNMEGDMTEKSILLIEK", "length": 352, "header": "sp|Q5RII3-1|GINM1_DANRE Isoform 1 of Glycoprotein integral membrane protein 1 OS=Danio rerio OX=7955 GN=ginm1 PE=2 SV=1 CANONICAL=Q5RII3-1" }, "isoforms": [ { "isoform_ac": "Q5RII3-1", "url": "https://www.uniprot.org/uniprotkb/Q5RII3/entry#Q5RII3-1", "sequence": { "sequence": "MASRCKIHLTVAYLLILCILASAQSKQMTTETVVLNVTALSEINQTKYNVQINLNIGLLDNDIFINGAPLKPSGVTRMTCPALLLDGYNVSSGNSVDGLVSCELRLMVNQSYVQSDAAEQLLFLVLSQEIIQLADEKVQQPEISEVEIMWNQSSEQMTQVTSIYPSARSKLSIIPRENDVLVTDASVQSAVEDQVRNTTSHYLLKNSETTQEEIAAPGKLPETPLRMDPETLYESREEEERRSDSLLLEPPLSGSMSSYSVACQWVEKLRDKLRRFLSDSVPLFFLVMWVVVVGVAGSAVVIKILDLIFPSCEHRGFFHLNPETLMPDDEKVSLIDNMEGDMTEKSILLIEK", "length": 352, "header": "sp|Q5RII3-1|GINM1_DANRE Isoform 1 of Glycoprotein integral membrane protein 1 OS=Danio rerio OX=7955 GN=ginm1 PE=2 SV=1 CANONICAL=Q5RII3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 109, "start_aa": "Asn", "end_pos": 109, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn109", "evidence": [ { "id": "Q5RII3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RII3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 151, "start_aa": "Asn", "end_pos": 151, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn151", "evidence": [ { "id": "Q5RII3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RII3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 197, "start_aa": "Asn", "end_pos": 197, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn197", "evidence": [ { "id": "Q5RII3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RII3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 36, "start_aa": "Asn", "end_pos": 36, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn36", "evidence": [ { "id": "Q5RII3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RII3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 44, "start_aa": "Asn", "end_pos": 44, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn44", "evidence": [ { "id": "Q5RII3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RII3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 89, "start_aa": "Asn", "end_pos": 89, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn89", "evidence": [ { "id": "Q5RII3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RII3#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "Q5RII3", "url": "https://www.uniprot.org/uniprotkb/Q5RII3" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:555775", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555775", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZJB2-1", "protein_name": "Glycosylated integral membrane protein 1", "gene_name": "Ginm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGALSAPLPVRLLLFVALPAAGWLTTNAPRPLSTVPQDGIRINVTTQKDNGEVSKEQVVLNITYESGQVYVNDLPVNSGVTRISCQTSIVKSENLENLEEKEYFGIVTVRILLRERPVTYSTSSQLIVIQEEVVELDGRQAQQKNVTEINILVKNQRVLRRSNFFLPLEESMLYSISQDSDILFTPPDFSKKVGTVGSLQTTSHYLVGDLGTTVDGNALPGKLPETPLRAEPPSSYKVMCQWMEKLRKALCGFWSGVFPVLFMFLNVMVVGVLGAAGVIALLKLLFPVRENKGILQVDKMNGISVVPIILYPDGSEKTAEKLTDKTDI", "length": 329 }, "evidence": [ { "id": "RGD:1309759", "url": "https://alliancegenome.org/gene/RGD:1309759#orthology", "database": "AGR" }, { "id": "MGI:2384905", "url": "https://alliancegenome.org/gene/MGI:2384905#orthology", "database": "AGR" }, { "id": "HGNC:21074", "url": "https://alliancegenome.org/gene/HGNC:21074#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5900", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5900#orthology", "database": "AGR" }, { "id": "Q5RII3", "url": "https://omabrowser.org/oma/group/Q5RII3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NAD1-1", "protein_name": "Glycoprotein integral membrane 1", "gene_name": "GINM1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAALGRRGRRLLPLLLPLIAALHLSPSAALPLGQETIRVNVMMLKSNGEFHKGQVVFNITYVNGQVYLNDFPMRSGVAHITCQTVILENGSLDDTVEQQRLGTVSVRIMVHEWPLASSSDLQLIVIQEEVTEIDGRQVQQEEVSEIDILVKDLRVLRHSNYTVPLKESMLYSIPRDNDVLFTLPNLSGKDIQDPLQTTSQYLIWQVETTVDEETLPGKLPETPLRIEPPSSYKVMCQWVEDLRKWLCRFWFKSLPIFFNVMEVVVVGVIGAALILKVLKVIFPSCEPKGILLLDQMSYVPVITISLPSDAPDRKNNLDEKTCT", "length": 324 }, "evidence": [ { "id": "Q5RII3", "url": "https://omabrowser.org/oma/group/Q5RII3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "I3LCU1-1", "protein_name": "Glycosylated integral membrane protein 1", "gene_name": "GINM1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGASRAPLALQLLLLAALPAACWLTRGTLEPPLPPGALKDSIRINVTTLRDDGTESKEQVVLNITYESGQVYVNDFPVNRGVTRISCQTLIVKNENLENLEEKEYFGIVSVRILVHEWPMTSGSSLQLIVIQEEVVEMDGKQAQQRDVTEIDILVKNQGVLRHSNYTLPLEESMLHSISRDSDILFTLPSLSKKGESVSSLQTTSQYLIRNVETTVDEDALPGKLPETPLRAEPPSSYKVMCQWMEKFRKDLCRFWSSVFPVFFMFLNVMVVGIIGAVVVITILKVLFPVCEYKGILQLDKVNVIPVTALNLYSDGPEKTAEKPGDKTCI", "length": 331 }, "evidence": [ { "id": "Q5RII3", "url": "https://omabrowser.org/oma/group/Q5RII3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q91WR6-1", "protein_name": "Glycoprotein integral membrane protein 1", "gene_name": "Ginm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGGLSAPLSVRLLLFIALPAAGWLTTNAPRPPSTAPQNGIQINVTTLSKSGEESEEQVVLNITYERGQVYVNDLPVNSGVTRISCQTLIVKSENLEKLEEKHYFGIVTVRILVLERPVTYSASSQLIVIQGEVVEIDGRQAQQKNVTEIDILVKNQRVLRYSSYFLPLEESMLYSISQDSDILFTLPDFSKKGTVSSLQTTSHYLMGNVETTVDGNALPGKLPETPLRAEPPSSYKVMCQWMEKLRKALCRFWSSVVPVLFMFLDVMVVGVLGAAGVIAVLKLLFPVCENKGILQVDKMNGISVPIILYPDGSEKTAQKLTDKTDI", "length": 327 }, "evidence": [ { "id": "RGD:1309759", "url": "https://alliancegenome.org/gene/RGD:1309759#orthology", "database": "AGR" }, { "id": "MGI:2384905", "url": "https://alliancegenome.org/gene/MGI:2384905#orthology", "database": "AGR" }, { "id": "HGNC:21074", "url": "https://alliancegenome.org/gene/HGNC:21074#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5900", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5900#orthology", "database": "AGR" }, { "id": "Q5RII3", "url": "https://omabrowser.org/oma/group/Q5RII3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NU53-1", "protein_name": "Glycoprotein integral membrane protein 1", "gene_name": "GINM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGAPPGSLALRLLLFVALPASGWLTTGAPEPPPLSGAPQDGIRINVTTLKDDGDISKQQVVLNITYESGQVYVNDLPVNSGVTRISCQTLIVKNENLENLEEKEYFGIVSVRILVHEWPMTSGSSLQLIVIQEEVVEIDGKQVQQKDVTEIDILVKNRGVLRHSNYTLPLEESMLYSISRDSDILFTLPNLSKKESVSSLQTTSQYLIRNVETTVDEDVLPGKLPETPLRAEPPSSYKVMCQWMEKFRKDLCRFWSNVFPVFFQFLNIMVVGITGAAVVITILKVFFPVSEYKGILQLDKVDVIPVTAINLYPDGPEKRAENLEDKTCI", "length": 330 }, "evidence": [ { "id": "RGD:1309759", "url": "https://alliancegenome.org/gene/RGD:1309759#orthology", "database": "AGR" }, { "id": "MGI:2384905", "url": "https://alliancegenome.org/gene/MGI:2384905#orthology", "database": "AGR" }, { "id": "HGNC:21074", "url": "https://alliancegenome.org/gene/HGNC:21074#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5900", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5900#orthology", "database": "AGR" }, { "id": "Q5RII3", "url": "https://omabrowser.org/oma/group/Q5RII3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5RII3", "url": "https://www.uniprot.org/uniprotkb/Q5RII3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 36, 44, 89, 109, 151, 197 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 6 }, { "field": "total_sites", "count": 6 }, { "field": "n_linked_sites", "count": 6 }, { "field": "o_linked_sites", 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The reference sequence was derived from JBMGRA010000020.1. On Sep 1, 2006 this sequence version replaced XP_697044.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001038629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038629" } ] }, { "annotation": "Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling.", "evidence": [ { "database": "UniProtKB", "id": "Q5RIK6", "url": "https://www.uniprot.org/uniprotkb/Q5RIK6#function" }, { "database": "UniProtKB", "id": "ARBA00054921", "url": "https://www.uniprot.org/uniprotkb/ARBA00054921#function" } ] }, { "annotation": "To better characterize the function of SEL1L in the early stages of embryonic development, we turned to the zebrafish model (Danio rerio). 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00040", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00040", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-382556", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-382556", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-5358346", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5358346", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9931269", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9931269", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001038629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038629", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5RIK6", 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CANONICAL=Q5RIK6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Positive correlation between gene coexpression and positional clustering in the zebrafish genome.", "journal": "BMC Genomics", "date": "2009", "authors": "Ng Yen Kaow, Wu Wei, Zhang Louxin", "evidence": [ { "database": "UniProtKB", "id": "Q5RIK6", "url": "https://www.uniprot.org/uniprotkb/Q5RIK6" } ], "reference": [ { "type": "PubMed", "id": "19159490", "url": "https://glygen.org/publication/PubMed/19159490" } ] }, { "title": "Deep mRNA sequencing analysis to capture the transcriptome landscape of zebrafish embryos and larvae.", "journal": "PLoS ONE", "date": "2013", "authors": "Yang Hongxing, Zhou Yan, Gu Jianlei, Xie Shuying, Xu Yao, Zhu Genfeng, Wang Lei, Huang Jiyue, Ma Hong, Yao Jihua", "evidence": [ { "database": "UniProtKB", "id": "Q5RIK6", "url": "https://www.uniprot.org/uniprotkb/Q5RIK6" } ], "reference": [ { "type": "PubMed", "id": "23700457", "url": "https://glygen.org/publication/PubMed/23700457" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "Q5RIK6", "url": "https://www.uniprot.org/uniprotkb/Q5RIK6" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "Q5RIK6", "url": "https://www.uniprot.org/uniprotkb/Q5RIK6" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "Q5RIK6", "url": "https://www.uniprot.org/uniprotkb/Q5RIK6" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] }, { "title": "Sel1l knockdown negatively influences zebrafish embryos endothelium.", "journal": "J. Cell. Physiol.", "date": "2018", "authors": "Barbieri Andrea, Carra Silvia, De Blasio Pasquale, Cotelli Franco, Biunno Ida", "evidence": [ { "database": "UniProtKB", "id": "Q5RIK6", "url": "https://www.uniprot.org/uniprotkb/Q5RIK6" }, { "database": "RefSeq", "id": "NP_001038629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038629" } ], "reference": [ { "type": "PubMed", "id": "29215726", "url": "https://glygen.org/publication/PubMed/29215726" } ] } ], "pathway": [ { "id": "dre:568615", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568615", "resource": "KEGG Pathway" }, { "id": "R-DRE-382556", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-382556", "resource": "Reactome", "description": "ABC-family protein mediated transport" }, { "id": "R-DRE-5358346", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5358346", "resource": "Reactome", "description": "Hedgehog ligand biogenesis" }, { "id": "R-DRE-9931269", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9931269", "resource": "Reactome", "description": "AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1SYF7-1", "protein_name": "Protein sel-1 homolog 1", "gene_name": "SEL1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRVGVRLTLLLCVVLLGSASVSSDEEGDQDESLDSKTSLPSDESVKDHSPTGRVVAGQLFLESEESEVESPIQEEEDSLRSQEGESVAEEINFLESPNPENRDYEEPTKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLSQNIQAAKGMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTHLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPVPRPPGPRPAPPQQEGPPEQQAPQ", "length": 794 }, "evidence": [ { "id": "Q5RIK6", "url": "https://omabrowser.org/oma/group/Q5RIK6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1MGJ5-1", "protein_name": "Protein sel-1 homolog 1", "gene_name": "SEL1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRVWVGLTLLLWAVLLGSALASSDEEGNQDESVDSKTSVPSDESVENHSPASRVIAGQIFLDSEESELESPPQEEEGNLRSQEGESIAEEISFLESPNPENKDYEELTKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAARRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVSYALLFGDYLTQNIQAAKEMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYSSYKDGDSNAAVIQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDIFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPVPRPPGPRPAPPQQEGPPEQPPLQ", "length": 794 }, "evidence": [ { "id": "Q5RIK6", "url": "https://omabrowser.org/oma/group/Q5RIK6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q05787-1", "protein_name": "ERAD-associated E3 ubiquitin-protein ligase component HRD3", "gene_name": "HRD3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MITLLLYLCVICNAIVLIRADSIADPWPEARHLLNTIAKSRDPMKEAAMEPNADEFVGFYVPMDYSPRNEEKNYQSIWQNEITDSQRHIYELLVQSSEQFNNSEATYTLSQIHLWSQYNFPHNMTLAHKYLEKFNDLTHFTNHSAIFDLAVMYATGGCASGNDQTVIPQDSAKALLYYQRAAQLGNLKAKQVLAYKYYSGFNVPRNFHKSLVLYRDIAEQLRKSYSRDEWDIVFPYWESYNVRISDFESGLLGKGLNSVPSSTVRKRTTRPDIGSPFIAQVNGVQMTLQIEPMGRFAFNGNDGNINGDEDDEDASERRIIRIYYAALNDYKGTYSQSRNCERAKNLLELTYKEFQPHVDNLDPLQVFYYVRCLQLLGHMYFTGEGSSKPNIHMAEEILTTSLEISRRAQGPIGRACIDLGLINQYITNNISQAISYYMKAMKTQANNGIVEFQLSKLATSFPEEKIGDPFNLMETAYLNGFIPAIYEFAVMIESGMNSKSSVENTAYLFKTFVDKNEAIMAPKLRTAFAALINDRSEVALWAYSQLAEQGYETAQVSAAYLMYQLPYEFEDPPRTTDQRKTLAISYYTRAFKQGNIDAGVVAGDIYFQMQNYSKAMALYQGAALKYSIQAIWNLGYMHEHGLGVNRDFHLAKRYYDQVSEHDHRFYLASKLSVLKLHLKSWLTWITREKVNYWKPSSPLNPNEDTQHSKTSWYKQLTKILQRMRHKEDSDKAAEDSHKHRTVVQNGANHRGDDQEEASEILGFQMEDLVTMGCILGIFLLSILMSTLAARRGWNVRFNGAQLNANGNRQQEQQQQQQAQGPPGWDFNVQIFAI", "length": 833 }, "evidence": [ { "id": "MGI:1329016", "url": "https://alliancegenome.org/gene/MGI:1329016#orthology", "database": "AGR" }, { "id": "HGNC:10717", "url": "https://alliancegenome.org/gene/HGNC:10717#orthology", "database": "AGR" }, { "id": "Q5RIK6", "url": "https://omabrowser.org/oma/group/Q5RIK6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q80Z70-1", "protein_name": "Protein sel-1 homolog 1", "gene_name": "Sel1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQVRVRLLLLLCAVLLGSAAASSDEETNQDESLDSKGALPTDGSVKDHTTGKVVLLARDLLILKDSEVESLLQDEEESSKSQEEVSVTEDISFLDSPNPSSKTYEELKRVRKPVLTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKTDEKWGFCETEEDAAKRRQMQEAEAIYQSGMKILNGSTRKNQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNIQAAKEMFEKLTEEGSPKGQTGLGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDDDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIREANIRDLFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDIPVPRPPGPRPAPPQQEGPPEQQPPQ", "length": 794 }, "evidence": [ { "id": "MGI:1329016", "url": "https://alliancegenome.org/gene/MGI:1329016#orthology", "database": "AGR" }, { "id": "HGNC:10717", "url": "https://alliancegenome.org/gene/HGNC:10717#orthology", "database": "AGR" }, { "id": "Q5RIK6", "url": "https://omabrowser.org/oma/group/Q5RIK6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9LM25-1", "protein_name": "ERAD-associated E3 ubiquitin-protein ligase component HRD3A", "gene_name": "HRD3A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MRILSYGIVILSLLVFSFIEFGVHARPVVLVLSNDDLNSGGDDNGVGESSDFDEFGESEPKSEEELDPGSWRSIFEPDDSTVQAASPQYYSGLKKILSAASEGNFRLMEEAVDEIEAASSAGDPHAQSIMGFVYGIGMMREKSKSKSFLHHNFAAAGGNMQSKMALAFTYLRQDMHDKAVQLYAELAETAVNSFLISKDSPVVEPTRIHSGTEENKGALRKSRGEEDEDFQILEYQAQKGNANAMYKIGLFYYFGLRGLRRDHTKALHWFLKAVDKGEPRSMELLGEIYARGAGVERNYTKALEWLTLAAKEGLYSAFNGIGYLYVKGYGVDKKNYTKAREYFEKAVDNEDPSGHYNLGVLYLKGIGVNRDVRQATKYFFVAANAGQPKAFYQLAKMFHTGVGLKKNLEMATSFYKLVAERGPWSSLSRWALEAYLKGDVGKALILYSRMAEMGYEVAQSNAAWILDKYGERSMCMGVSGFCTDKERHERAHSLWWRASEQGNEHAALLIGDAYYYGRGTERDFVRAAEAYMHAKSQSNAQAMFNLGYMHEHGQGLPFDLHLAKRYYDESLQSDAAARLPVTLALASLWLRRNYADTVLVRVVDSLPEVYPKVETWIENVVFEEGNATILTLFVCLITILYLRERQRRQVVVVADPVAADVAQPLDADVAQHLAAFPR", "length": 678 }, "evidence": [ { "id": "Q5RIK6", "url": "https://omabrowser.org/oma/group/Q5RIK6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9UBV2-1", "protein_name": "Protein sel-1 homolog 1", "gene_name": "SEL1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVRIGLTLLLCAVLLSLASASSDEEGSQDESLDSKTTLTSDESVKDHTTAGRVVAGQIFLDSEESELESSIQEEEDSLKSQEGESVTEDISFLESPNPENKDYEEPKKVRKPALTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKADEKWGFCETEEEAAKRRQMQEAEMMYQTGMKILNGSNKKSQKREAYRYLQKAASMNHTKALERVSYALLFGDYLPQNIQAAREMFEKLTEEGSPKGQTALGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMVLGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDGDYNAAVIQYLLLAEQGYEVAQSNAAFILDQREASIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIRETNIRDMFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDMPAPRPPGPRPAPPQQEGPPEQQPPQ", "length": 794 }, "evidence": [ { "id": "MGI:1329016", "url": "https://alliancegenome.org/gene/MGI:1329016#orthology", "database": "AGR" }, { "id": "HGNC:10717", "url": "https://alliancegenome.org/gene/HGNC:10717#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-122", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-122#orthology", "database": "AGR" }, { "id": "Q5RIK6", "url": "https://omabrowser.org/oma/group/Q5RIK6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V415-1", "protein_name": "HMG-coA reductase degradation 3, isoform B", "gene_name": "Hrd3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKANSWMCLLALLLAWQLRAEELQGPNIDGTGSSLGSATGTGTGTGLGTGTATPTLPNEPSTQAEAEEVTTAESESRVPSESNERKADKPKESTKFASRTKVMPASLFERLWNESLIRRQKLKAEIERIEAKRKSTEVLELTPDQIEAQTVYDNAMDMLAKPSTDKRVAMILLKKAAAFNHLKARAELAWAALLGQWMDFDFNHAVDEFESLANEGVPEAHMGLGFLYSVGVGGKNVSQPLALIHYSLAALGDNTPAQMAMGYRYLYGINVPISCEKALIHYKRVAKKVASKITFANGPVVHRVRLLDDLENPGSSETEIVDYYKLLADKGDIQSQVGLGQVYYQGGKVTEQDHQKALEYFKMAADAGSAVGIAFLGKLYLEGSDQIRADNDAAFGYFSKAAEMGDPVGQSGLGLMYLKGLGVPKDSIKALSYFTQAADQGWVDGQLQLGNMYFTGNGVKTDYKLAFKYFNLATQSGHVLAYYNLGVMNAYGMGMLRSCPAAVEFFKTVSERGRWSSRLMMAYSDYKNNRIDEAYMQYSLMAEMGYEVAQSNAAFLLDRKEVHVFNDRHEDLIRAFYYWKRAAGQGYSAAQVKLGDYYYYGWGTSTDFETAAALYRKASEQQYNAQAMFNLGYMHEQGLGMKKDWHLAKRLYDLAAETNSDAKVPVAIALFKLQMLATIESIKESPYRFIFYMDENIAANWDLYMITVLTLLLGIIMYMRRPFQQPDQPAQQPAADDIAAAPVNLAPVGAEAAPVAAVVEGVGVTPPAAAVSSHDAVAASSSTETSSTTATSLVDAASQGGSGTTSAAPDGANTLDPTG", "length": 819 }, "evidence": [ { "id": "MGI:1329016", "url": "https://alliancegenome.org/gene/MGI:1329016#orthology", "database": "AGR" }, { "id": "HGNC:10717", "url": "https://alliancegenome.org/gene/HGNC:10717#orthology", "database": "AGR" }, { "id": "Q5RIK6", "url": "https://omabrowser.org/oma/group/Q5RIK6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z2G6-1", "protein_name": "Protein sel-1 homolog 1", "gene_name": "Sel1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQVRVRLSLLLLCAVLLGSAAATSDDKTNQDDSLDSKSSLPTDESVKDHTTTGKVVAGQIFVDSEEAEVESLLQDEEDSSKTQEEEISFLESPNPSSKTYEELKRVRKPVLTAIEGTAHGEPCHFPFLFLDKEYDECTSDGREDGRLWCATTYDYKTDEKWGFCETEEDAAKRRQMQEAEMIYQAGMKILNGSNRKSQKREAYRYLQKAAGMNHTKALERVSYALLFGDYLTQNIQAAKEMFEKLTEEGSPKGQTGLGFLYASGLGVNSSQAKALVYYTFGALGGNLIAHMILGYRYWAGIGVLQSCESALTHYRLVANHVASDISLTGGSVVQRIRLPDEVENPGMNSGMLEEDLIQYYQFLAEKGDVQAQVGLGQLHLHGGRGVEQNHQRAFDYFNLAANAGNSHAMAFLGKMYSEGSDIVPQSNETALHYFKKAADMGNPVGQSGLGMAYLYGRGVQVNYDLALKYFQKAAEQGWVDGQLQLGSMYYNGIGVKRDYKQALKYFNLASQGGHILAFYNLAQMHASGTGVMRSCHTAVELFKNVCERGRWSERLMTAYNSYKDEDYNAAVVQYLLLAEQGYEVAQSNAAFILDQREATIVGENETYPRALLHWNRAASQGYTVARIKLGDYHFYGFGTDVDYETAFIHYRLASEQQHSAQAMFNLGYMHEKGLGIKQDIHLAKRFYDMAAEASPDAQVPVFLALCKLGVVYFLQYIREANIRDLFTQLDMDQLLGPEWDLYLMTIIALLLGTVIAYRQRQHQDIPVPRPPGPRPAPPQQEGPPEQQPPQ", "length": 790 }, "evidence": [ { "id": "MGI:1329016", "url": "https://alliancegenome.org/gene/MGI:1329016#orthology", "database": "AGR" }, { "id": "HGNC:10717", "url": "https://alliancegenome.org/gene/HGNC:10717#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-122", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-122#orthology", "database": "AGR" }, { "id": "Q5RIK6", "url": "https://omabrowser.org/oma/group/Q5RIK6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "Notch signaling pathway", "id": "GO:0007219", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007219", "evidence": [ { "database": "UniProtKB", "id": "Q5RIK6", "url": "https://www.uniprot.org/uniprotkb/Q5RIK6" } ], "pmid": "" }, { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "Q5RIK6", "url": "https://www.uniprot.org/uniprotkb/Q5RIK6" } ], "pmid": "" }, { "name": "ERAD pathway", "id": "GO:0036503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036503", "evidence": [ { "database": "UniProtKB", "id": "Q5RIK6", "url": "https://www.uniprot.org/uniprotkb/Q5RIK6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q5RIK6", "url": "https://www.uniprot.org/uniprotkb/Q5RIK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5RIK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIK6" }, { "id": "PS51092", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51092" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-II", "eco_id": "ECO_0000259", "start_pos": 105, "end_pos": 153, "start_aa": "Ala", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 591, "end_pos": 593 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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"total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5RIM0-1", "uniprot_ac": "Q5RIM0", "uniprot_id": "LYRM2_DANRE", "mass": { "chemical_mass": 10490.0, "monoisotopic_mass": 10490.0 }, "refseq": { "ac": "NP_001153303", "name": "LYR motif-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153303" }, "gene_names": [ { "name": "lyrm2", "type": "recommended", "evidence": [ { "id": "Q5RIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0" } ] }, { "name": "im:6909904", "type": "synonym", "evidence": [ { "id": "NP_001153303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153303" }, { "id": "Q5RIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0" } ] }, { "name": "lyrm2", "type": "synonym", "evidence": [ { "id": "NP_001153303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153303" } ] }, { "name": "si:dkey-181i3.3", "type": "synonym", "evidence": [ { "id": "NP_001153303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153303" }, { "id": "Q5RIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0" } ] }, { "name": "zgc:153586", "type": "synonym", "evidence": [ { "id": "NP_001153303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153303" }, { "id": "Q5RIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0" } ] } ], "protein_names": [ { "name": "LYR motif-containing protein 2", "type": "recommended", "evidence": [ { "id": "Q5RIM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0/entry#names_and_taxonomy" } ] }, { "name": "LYR motif-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001153303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153303" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC097217.1, SRR32588729.428405.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On or before Jul 2, 2025 this sequence version replaced XP_073789143.1, XP_697858.2. Sequence Note:.", "evidence": [ { "database": "RefSeq", "id": "NP_001153303", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153303" } ] }, { "annotation": "Involved in efficient integration of the N-module into mitochondrial respiratory chain complex I.", "evidence": [ { "database": "UniProtKB", "id": "Q5RIM0", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0#function" }, { "database": "UniProtKB", "id": "Q9NU23", "url": "https://www.uniprot.org/uniprotkb/Q9NU23#function" }, { "database": "UniProtKB", "id": "A0AC58I4I0", "url": "https://www.uniprot.org/uniprotkb/A0AC58I4I0#function" }, { "database": "UniProtKB", "id": "ARBA00044735", "url": "https://www.uniprot.org/uniprotkb/ARBA00044735#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RIM0", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "lyrm2", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040914-27", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040914-27", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5RIM0", "url": "https://alphafold.ebi.ac.uk/entry/Q5RIM0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000033138", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000033138", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20262", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20262", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "569076", "url": "https://www.ncbi.nlm.nih.gov/gene/569076", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045293", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045293", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569076", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569076", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMRDWAR", "url": "https://omabrowser.org/oma/group/YMRDWAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5RIM0", "url": "https://www.orthodb.org/?gene=Q5RIM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13675", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13675", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13675:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13675:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5RIM0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5RIM0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DRE-6799198", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6799198", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001153303", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153303", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58I4I0", "url": "https://www.uniprot.org/uniprotkb/A0AC58I4I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I4I0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I4I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RIM0", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RIM0-1", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040914-27", "url": "https://zfin.org/ZDB-GENE-040914-27", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAVSRLPPAALSLKQFLQRQKVLCLYRDLQRTIRRVPHESDRKYLRDWARDEFRRNKSNTDQDAIRMMISQAHNHLEELRRSLALAGC", "length": 88, "header": "sp|Q5RIM0-1|LYRM2_DANRE Isoform 1 of LYR motif-containing protein 2 OS=Danio rerio OX=7955 GN=lyrm2 PE=3 SV=1 CANONICAL=Q5RIM0-1" }, "isoforms": [ { "isoform_ac": "A0AC58I4I0-1", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0/entry#A0AC58I4I0-1", "sequence": { "sequence": "MAVSRLPPAALSLKQFLQRQKVLCLYRDLQRTIRRVPHESDRKYLRDWARDEFRRNKSNTDQDAIRMMISQAHNHLEELRRSLALAGC", "length": 88, "header": "tr|A0AC58I4I0-1|A0AC58I4I0_DANRE Computationally mapped isoform of LYR motif-containing protein 2 OS=Danio rerio OX=7955 GN=lyrm2 PE=3 SV=1 CANONICAL=Q5RIM0-1" }, "locus": {} }, { "isoform_ac": "Q5RIM0-1", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0/entry#Q5RIM0-1", "sequence": { "sequence": "MAVSRLPPAALSLKQFLQRQKVLCLYRDLQRTIRRVPHESDRKYLRDWARDEFRRNKSNTDQDAIRMMISQAHNHLEELRRSLALAGC", "length": 88, "header": "sp|Q5RIM0-1|LYRM2_DANRE Isoform 1 of LYR motif-containing protein 2 OS=Danio rerio OX=7955 GN=lyrm2 PE=3 SV=1 CANONICAL=Q5RIM0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "Q5RIM0", "url": "https://www.uniprot.org/uniprotkb/Q5RIM0" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:569076", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569076", "resource": "KEGG Pathway" }, { "id": "R-DRE-6799198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6799198", "resource": "Reactome", "description": "Complex I biogenesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XK83-1", "protein_name": "LYR motif-containing protein 2", "gene_name": "LYRM2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAARCGKKDLGLLVGARLNTSQQCAHVAKKANNILACIRNGAANKSREVIVPLCTALFLRRQQVLQLYRRILRALRDVPAEADRRHLQQWAREEFRRNKDATEEDAIRMMITQGHMQLRELQKALKLAKS", "length": 131 }, "evidence": [ { "id": "Q5RIM0", "url": "https://omabrowser.org/oma/group/Q5RIM0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "B2GV91-1", "protein_name": "LYR motif-containing protein 2", "gene_name": "Lyrm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASRLPPATLTLKQFMRRQQVLLLYRKILRAIKQIPSDSDRKYLQDWAREEFKRNKSATEEDTIRMMITQGNMQLKELERTLALAKS", "length": 88 }, "evidence": [ { "id": "RGD:1597334", "url": "https://alliancegenome.org/gene/RGD:1597334#orthology", "database": "AGR" }, { "id": "MGI:1917573", "url": "https://alliancegenome.org/gene/MGI:1917573#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040914-27", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040914-27#orthology", "database": "AGR" }, { "id": "HGNC:25229", "url": "https://alliancegenome.org/gene/HGNC:25229#orthology", "database": "AGR" }, { "id": "FB:FBgn0259832", "url": "https://alliancegenome.org/gene/FB:FBgn0259832#orthology", "database": "AGR" }, { "id": "Q5RIM0", "url": "https://omabrowser.org/oma/group/Q5RIM0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S0C3-1", "protein_name": "LYR motif-containing protein 2", "gene_name": "LYRM2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATSRLPPATLTLKQFMRRQQVLLLYRRILQAIRQVPNDSDRRYLKDWAREEFKRNKNATEEDTIRMMITQGNMQLKELEKTLALARS", "length": 88 }, "evidence": [ { "id": "Q5RIM0", "url": "https://omabrowser.org/oma/group/Q5RIM0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q32LM5-1", "protein_name": "LYR motif-containing protein 2", "gene_name": "LYRM2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATSRLPPATLTLKQFMRRQQVLLLYRRILQAIRQVPNDSDRKYLKDWAREEFKRNKSATEEDTIRMMITQGNMQLKELEKTLALARS", "length": 88 }, "evidence": [ { "id": "Q5RIM0", "url": "https://omabrowser.org/oma/group/Q5RIM0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6IGM9-1", "protein_name": "LYR motif-containing protein 2", "gene_name": "CG13191", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKLPKASLSLKQFMLRQEVLKLYREIFRTIRQVPDKNSQLELKSWARHDFQTNRHQSDEVAIKMLLQHGRRSLTELRTSLQLSGVSEGK", "length": 90 }, "evidence": [ { "id": "RGD:1597334", "url": "https://alliancegenome.org/gene/RGD:1597334#orthology", "database": "AGR" }, { "id": "MGI:1917573", "url": "https://alliancegenome.org/gene/MGI:1917573#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040914-27", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040914-27#orthology", "database": "AGR" }, { "id": "HGNC:25229", "url": "https://alliancegenome.org/gene/HGNC:25229#orthology", "database": "AGR" }, { "id": "FB:FBgn0259832", "url": "https://alliancegenome.org/gene/FB:FBgn0259832#orthology", "database": "AGR" }, { "id": "Q5RIM0", "url": "https://omabrowser.org/oma/group/Q5RIM0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8R033-1", "protein_name": "LYR motif-containing protein 2", "gene_name": "Lyrm2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASRLPPAALTLKQFMRRQQVLLLYRKILRAIRQVPSDSDRKYLQDWAREEFKRNKSATEEDTIRMMITQGNMQLKELERTLALANS", "length": 88 }, "evidence": [ { "id": "RGD:1597334", "url": "https://alliancegenome.org/gene/RGD:1597334#orthology", "database": "AGR" }, { "id": "MGI:1917573", "url": "https://alliancegenome.org/gene/MGI:1917573#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040914-27", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040914-27#orthology", "database": "AGR" }, { "id": "HGNC:25229", "url": "https://alliancegenome.org/gene/HGNC:25229#orthology", "database": "AGR" }, { "id": "FB:FBgn0259832", "url": "https://alliancegenome.org/gene/FB:FBgn0259832#orthology", "database": "AGR" }, { "id": "Q5RIM0", "url": "https://omabrowser.org/oma/group/Q5RIM0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NU23-1", "protein_name": "LYR motif-containing protein 2", "gene_name": "LYRM2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASRLPPATLTLKQFVRRQQVLLLYRRILQTIRQVPNDSDRKYLKDWAREEFRRNKSATEEDTIRMMITQGNMQLKELEKTLALAKS", "length": 88 }, "evidence": [ { "id": "RGD:1597334", "url": 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The reference sequence was derived from JBMGRA010000020.1. 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"Putative peptidyl-tRNA hydrolase PTRHD1", "gene_name": "Ptrhd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRKVRPASLMIRKMACSGVEPQILVQYLVLRKDLSQAPFSWPTGALVAQACHAATAALHLHRDHPHTAAYLRELGRMRKVVLEAADETTLKELAETLQQKNIDHTLWLEQPENIATCIALRPYPKEEVSQYLKKFRLFK", "length": 140 }, "evidence": [ { "id": "MGI:1916959", "url": "https://alliancegenome.org/gene/MGI:1916959#orthology", "database": "AGR" }, { "id": "HGNC:33782", "url": "https://alliancegenome.org/gene/HGNC:33782#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081110-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081110-2#orthology", "database": "AGR" }, { "id": "Q5RIN6", "url": "https://omabrowser.org/oma/group/Q5RIN6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZBG6-1", "protein_name": "peptidyl-tRNA hydrolase", "gene_name": "Ptrhd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRKMRPAILMIRKMAGSGVEPQILVQYLVLRKDLSQAPFSWPTGALVAQACHAATAALHLHRDHPHTAAYLRELGRMRKVVLEAADETTLKELAETLQQKNVDHTLWLEQPENIATCIALRPYPKEEVSQYLKKFRLFK", "length": 140 }, "evidence": [ { "id": "MGI:1916959", "url": "https://alliancegenome.org/gene/MGI:1916959#orthology", "database": "AGR" }, { "id": "HGNC:33782", "url": "https://alliancegenome.org/gene/HGNC:33782#orthology", "database": "AGR" }, { "id": "Q5RIN6", "url": "https://omabrowser.org/oma/group/Q5RIN6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3SZ85-1", "protein_name": "Putative peptidyl-tRNA hydrolase PTRHD1", "gene_name": "PTRHD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MHRGVGPAFQLSRKMAASGGEPQILVQYLVLRKDLTQPPFSWPAGAVVAQACHAATAALHLHRDHPHTAAYLRELERMRKVVLEAPDETTLKLLAETLQQKNIDHKLWMEQPENIPTCIALRPYPKEEVSQYLKKFRLFK", "length": 140 }, "evidence": [ { "id": "Q5RIN6", "url": "https://omabrowser.org/oma/group/Q5RIN6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6GMV3-1", "protein_name": "Putative peptidyl-tRNA hydrolase PTRHD1", "gene_name": "PTRHD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHRGVGPAFRVVRKMAASGAEPQVLVQYLVLRKDLSQAPFSWPAGALVAQACHAATAALHTHRDHPHTAAYLQELGRMRKVVLEAPDETTLKELAETLQQKNIDHMLWLEQPENIATCIALRPYPKEEVGQYLKKFRLFK", "length": 140 }, "evidence": [ { "id": "MGI:1916959", "url": "https://alliancegenome.org/gene/MGI:1916959#orthology", "database": "AGR" }, { "id": "HGNC:33782", "url": "https://alliancegenome.org/gene/HGNC:33782#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081110-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081110-2#orthology", "database": "AGR" }, { "id": "Q5RIN6", "url": "https://omabrowser.org/oma/group/Q5RIN6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VET3-1", "protein_name": "peptidyl-tRNA hydrolase", "gene_name": "Dmel\\CG14903", 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"https://www.uniprot.org/uniprotkb/Q5RIQ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "klf11a", "url": "https://www.uniprot.org/uniprotkb/Q5RIQ4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-3568", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3568", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd21584", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21584", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "560787", "url": "https://www.ncbi.nlm.nih.gov/gene/560787", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein 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Genes Evol.", "date": "2007", "authors": "Mu\u00f1oz-Descalzo Silvia, Belacortu Yaiza, Paricio Nuria", "evidence": [ { "database": "UniProtKB", "id": "Q5RIQ4", "url": "https://www.uniprot.org/uniprotkb/Q5RIQ4" } ], "reference": [ { "type": "PubMed", "id": "17333257", "url": "https://glygen.org/publication/PubMed/17333257" } ] }, { "title": "Role of Penaeus monodon Kruppel-like factor (PmKLF) in infection by white spot syndrome virus.", "journal": "Dev. Comp. Immunol.", "date": "2012", "authors": "Chang Li-Kwan, Huang Ping-Han, Shen Wei-Tao, Yang Shu-Han, Liu Wang-Jing, Lo Chu-Fang", "evidence": [ { "database": "UniProtKB", "id": "Q5RIQ4", "url": "https://www.uniprot.org/uniprotkb/Q5RIQ4" } ], "reference": [ { "type": "PubMed", "id": "21740926", "url": "https://glygen.org/publication/PubMed/21740926" } ] }, { "title": "Research resource: whole transcriptome RNA sequencing detects multiple 1alpha,25-dihydroxyvitamin D(3)-sensitive metabolic pathways in developing zebrafish.", "journal": "Mol. Endocrinol.", "date": "2012", "authors": "Craig Theodore A, Zhang Yuji, McNulty Melissa S, Middha Sumit, Ketha Hemamalini, Singh Ravinder J, Magis Andrew T, Funk Cory, Price Nathan D, Ekker Stephen C, Kumar Rajiv", "evidence": [ { "database": "UniProtKB", "id": "Q5RIQ4", "url": "https://www.uniprot.org/uniprotkb/Q5RIQ4" } ], "reference": [ { "type": "PubMed", "id": "22734042", "url": "https://glygen.org/publication/PubMed/22734042" } ] }, { "title": "Transcriptome analysis of the zebrafish model of Diamond-Blackfan anemia from RPS19 deficiency via p53-dependent and -independent pathways.", "journal": "PLoS ONE", "date": "2013", "authors": "Jia Qiong, Zhang Qian, Zhang Zhaojun, Wang Yaqin, Zhang Wanguang, Zhou Yang, Wan Yang, Cheng Tao, Zhu Xiaofan, Fang Xiangdong, Yuan Weiping, Jia Haibo", "evidence": [ { "database": "UniProtKB", "id": "Q5RIQ4", "url": "https://www.uniprot.org/uniprotkb/Q5RIQ4" } ], "reference": [ { "type": "PubMed", "id": "23990987", "url": "https://glygen.org/publication/PubMed/23990987" } ] }, { "title": "Genome-wide analysis of the zebrafish Klf family identifies two genes important for erythroid maturation.", "journal": "Dev. Biol.", "date": "2015", "authors": "Xue Yuanyuan, Gao Shuai, Liu Feng", "evidence": [ { "database": "UniProtKB", "id": "Q5RIQ4", "url": "https://www.uniprot.org/uniprotkb/Q5RIQ4" } ], "reference": [ { "type": "PubMed", "id": "26015096", "url": "https://glygen.org/publication/PubMed/26015096" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "Q5RIQ4", "url": "https://www.uniprot.org/uniprotkb/Q5RIQ4" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Characterization and phylogenetic analysis of Kruppel-like transcription factor (KLF) gene family in tree shrews (Tupaia belangeri chinensis).", "journal": "Oncotarget", "date": "2017", "authors": "Shao M, Ge GZ, Liu WJ, Xiao J, Xia HJ, Fan Y, Zhao F, He BL, Chen C", "evidence": [ { "database": "UniProtKB", "id": "Q5RIQ4", "url": "https://www.uniprot.org/uniprotkb/Q5RIQ4" } ], "reference": [ { "type": "PubMed", "id": "28032601", "url": "https://glygen.org/publication/PubMed/28032601" } ] } ], "pathway": [ { "id": "dre:560787", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560787", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NAI0-1", "protein_name": "Krueppel-like factor 11b", "gene_name": "klf11b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSTRQFTNMEEICKGARMEVCEDFLDVKKNSEYSSCSALEYNDLEAAEALVYMSFWSQMSPKPNVFKPRPLTPASDSCDSLLHPEPPETPKDFVSLSSLCMTPPHSPSFTETSNITSVPASPSPLTRPCPSLPSPQRSACPTMASITQVPSSGHPTERTTPPPCRAMATSVIRHTADSFLYQNIPQAVQPQKTEKAPSSPSLCHQPLIDTTTACQSSRSPSKEEKLFITSSTPHSPPPTSSPPIICQMFPMAQPGVISATFIQKPSPGVKSILPQPLLMSSPVPQGTVMFVMPQSPVSSTQQCQQTVMTLGNTKLLPLAPAPVYVPSGQSSATQVDFSRRRNYVCNFPGCRKTYFKSSHLKAHLRTHTGEKPFSCNWEGCDKKFARSDELSRHRRTHTGEKKFVCPVCERRFMRSDHLTKHARRHMTTKKIPSWQTEVRNLNKITAAKTLPTGTALPVSMLLPASN", "length": 466 }, "evidence": [ { "id": "MGI:2653368", "url": "https://alliancegenome.org/gene/MGI:2653368#orthology", "database": "AGR" }, { "id": "HGNC:11811", "url": "https://alliancegenome.org/gene/HGNC:11811#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PTS6-1", "protein_name": "KLF transcription factor 11", "gene_name": "Klf11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5RIV7-1", "uniprot_ac": "Q5RIV7", "uniprot_id": "PTHD1_DANRE", "mass": { "chemical_mass": 102383.0, "monoisotopic_mass": 102383.0 }, "refseq": { "ac": "NP_001025356", "name": "patched domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025356" }, "gene_names": [ { "name": "ptchd1", "type": "recommended", "evidence": [ { "id": "Q5RIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7" } ] }, { "name": "ptchd1", "type": "synonym", "evidence": [ { "id": "NP_001025356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025356" } ] }, { "name": "ptchd4", "type": "synonym", "evidence": [ { "id": "NP_001025356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025356" } ] }, { "name": "si:ch211-105n9.1-like protein", "type": "synonym", "evidence": [ { "id": "NP_001025356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025356" } ] }, { "name": "si:ch211-105n9.1", "type": "synonym", "evidence": [ { "id": "NP_001025356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025356" }, { "id": "Q5RIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7" } ] } ], "protein_names": [ { "name": "Patched domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "Q5RIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7/entry#names_and_taxonomy" } ] }, { "name": "patched domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001025356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025356" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01031680.1, SRR32588719.6817813.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476730, SAMEA4476734 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. On Aug 6, 2005 this sequence version replaced XP_692546.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025356" } ] }, { "annotation": "Can bind cholesterol in vitro.", "evidence": [ { "database": "UniProtKB", "id": "Q5RIV7", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7#function" }, { "database": "UniProtKB", "id": "Q96NR3", "url": "https://www.uniprot.org/uniprotkb/Q96NR3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RIV7", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ptchd1", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041001-178", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-178", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5RIV7", "url": "https://alphafold.ebi.ac.uk/entry/Q5RIV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000008249", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000008249", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "562268", "url": "https://www.ncbi.nlm.nih.gov/gene/562268", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "564097", "url": "https://www.ncbi.nlm.nih.gov/gene/564097", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000731", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000731", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564097", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564097", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GHQHTSH", "url": "https://omabrowser.org/oma/group/GHQHTSH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5RIV7", "url": "https://www.orthodb.org/?gene=Q5RIV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10796", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10796", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10796:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10796:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10796:SF36", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10796:SF36", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02460", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02460", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5RIV7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5RIV7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025356", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025356", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58IRK4", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRK4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RIV7", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RIV7-1", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041001-178", "url": "https://zfin.org/ZDB-GENE-041001-178", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLRQVIHRGLKASFYWLGLFVSRHPVFFLTVPAVLTIIFGSTVLSRFKPETDLEILVAPTHSLAKIERSLANSLFPIDQSKHKLYSDLHTPGRYGRLILLARSGGNILELAEQVLQVHKKVLDMRVNYKGFNYTFAHLCVLRHRDKRCLLDDIITIFEDIRLAVLSNSTFSKVPVSYPNTTLKDGRVSFIGHQLGGVALPANNRDQQVKFARAIQITYYLRNLGPVVQDIIAEKWETEFCKLVHQLATDSQELHIQSLTSFSLWRDFHKTGVLAKSEVLVSLVLVLLAATISSSMRDCLRGKPFLGLLGVLTICIANVTAAGIFFISDGKFNSTLLGIPFFAMGHGTKGVFELLAGWRRTRESLPFKERVADAFADVMVCYTMTSSLYIITFGMGASPFTNIESVKVFCQSMCVAVLVNYFYVFSFYGSCLVFAGQLEQNRYHSVFCCKIPSVEYLDRQPTWFKTMMSDGHDLSTHHDSVPYQNHFIQHFLREHYTEWITNTYVKPFVVILYLIYASFSFMGCLQISDGSNIINLLASNSPSVSFALTQQKYFSNYSPVIGFYIYEPIEYWNSTVQEHLKTLGQGFNKISWIDNYFHFLRVVNISASTKSDFISILKTSFLRSPEYQHFVDDIIFSKNGAEYDIIASKMYLVARTTEKTREEVVELLERLRPLSLINSIKFIVFNPTFVFMDRYSSSIISPILTSGFSVLTILILTFFLVINPLGNFWLILTVTSVELGVLGLMTLWNVDMDSISILCLIYTLNFAMDHCAPHLYTFVLATEHTRTQCIKISLEEHGAAILQNTSCFVIGIMPLLFVPSNLTYTLFKCSLLTAGCTVLHCFVILPVFLTFFPPSKKRHKKKKRAKRKEREREREREREREEIECIEVRENPDHVTNV", "length": 897, "header": "sp|Q5RIV7-1|PTHD1_DANRE Isoform 1 of Patched domain-containing protein 1 OS=Danio rerio OX=7955 GN=ptchd1 PE=3 SV=1 CANONICAL=Q5RIV7-1" }, "isoforms": [ { "isoform_ac": "A0AC58IRK4-1", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7/entry#A0AC58IRK4-1", "sequence": { "sequence": "MLSSWRRTREDQHVKERVAAVFSDCMLPFTASTALHVVTFGIGASPFTNIEAVRLFCQNACISVLFNYLYILTFYGSNLVFAGYLENNYRHSLFCRRVPKPELLQQKPAWYRFLMYTHYNEEATEAGPLCAYESHLLVAFMKRYYCDWITNTYVKPFVVLFYLVYVSFALMGYLQVSEGSDLSNVVATETSTIAYTRAQQRYFSSYSPVIGFYIYESIEYWNTSVQEDLLEYIKGFERISWFESYLNYLHGLNITTSLSRSNFTERLRSGFLRQPRYVHFTDDIIFAKRSDGEFDVVASRMFLIAKTTENKREEMSILLDTLRKLSLTSRVKFIIFNPSFVYMDRYASSVGAPLKNSCIAALFLLFFSTFLAADPLVNAWLTVTVASVEFGLVGFMTLWRVELDCVSVLCLIYGVNYAVDSSAPLVSAFALGRESTRTRWVKLALEQHGVPALQSYLCYGAALLPLAAVPSNLTRTLFRCLFLTAIITAFHCLAILPVLLTFLPPSKKKRRERKNAAENREEIECVEMVDSTRVVDQITTV", "length": 541, "header": "tr|A0AC58IRK4-1|A0AC58IRK4_DANRE Computationally mapped isoform of Patched domain-containing protein 1 isoform X2 OS=Danio rerio OX=7955 GN=ptchd1 PE=3 SV=1 CANONICAL=Q5RIV7-1" }, "locus": {} }, { "isoform_ac": "Q5RIV7-1", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7/entry#Q5RIV7-1", "sequence": { "sequence": "MLRQVIHRGLKASFYWLGLFVSRHPVFFLTVPAVLTIIFGSTVLSRFKPETDLEILVAPTHSLAKIERSLANSLFPIDQSKHKLYSDLHTPGRYGRLILLARSGGNILELAEQVLQVHKKVLDMRVNYKGFNYTFAHLCVLRHRDKRCLLDDIITIFEDIRLAVLSNSTFSKVPVSYPNTTLKDGRVSFIGHQLGGVALPANNRDQQVKFARAIQITYYLRNLGPVVQDIIAEKWETEFCKLVHQLATDSQELHIQSLTSFSLWRDFHKTGVLAKSEVLVSLVLVLLAATISSSMRDCLRGKPFLGLLGVLTICIANVTAAGIFFISDGKFNSTLLGIPFFAMGHGTKGVFELLAGWRRTRESLPFKERVADAFADVMVCYTMTSSLYIITFGMGASPFTNIESVKVFCQSMCVAVLVNYFYVFSFYGSCLVFAGQLEQNRYHSVFCCKIPSVEYLDRQPTWFKTMMSDGHDLSTHHDSVPYQNHFIQHFLREHYTEWITNTYVKPFVVILYLIYASFSFMGCLQISDGSNIINLLASNSPSVSFALTQQKYFSNYSPVIGFYIYEPIEYWNSTVQEHLKTLGQGFNKISWIDNYFHFLRVVNISASTKSDFISILKTSFLRSPEYQHFVDDIIFSKNGAEYDIIASKMYLVARTTEKTREEVVELLERLRPLSLINSIKFIVFNPTFVFMDRYSSSIISPILTSGFSVLTILILTFFLVINPLGNFWLILTVTSVELGVLGLMTLWNVDMDSISILCLIYTLNFAMDHCAPHLYTFVLATEHTRTQCIKISLEEHGAAILQNTSCFVIGIMPLLFVPSNLTYTLFKCSLLTAGCTVLHCFVILPVFLTFFPPSKKRHKKKKRAKRKEREREREREREREEIECIEVRENPDHVTNV", "length": 897, "header": "sp|Q5RIV7-1|PTHD1_DANRE Isoform 1 of Patched domain-containing protein 1 OS=Danio rerio OX=7955 GN=ptchd1 PE=3 SV=1 CANONICAL=Q5RIV7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 132, "start_aa": "Asn", "end_pos": 132, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn132", "evidence": [ { "id": "Q5RIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 167, "start_aa": "Asn", "end_pos": 167, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn167", "evidence": [ { "id": "Q5RIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 179, "start_aa": "Asn", "end_pos": 179, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn179", "evidence": [ { "id": "Q5RIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 332, "start_aa": "Asn", "end_pos": 332, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn332", "evidence": [ { "id": "Q5RIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 572, "start_aa": "Asn", "end_pos": 572, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn572", "evidence": [ { "id": "Q5RIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 603, "start_aa": "Asn", "end_pos": 603, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn603", "evidence": [ { "id": "Q5RIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 803, "start_aa": "Asn", "end_pos": 803, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn803", "evidence": [ { "id": "Q5RIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "Q5RIV7", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:564097", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564097", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B9EKX1-1", "protein_name": "Patched domain-containing protein 4", "gene_name": "Ptchd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCFLRRPGAPASWIWWRMLRQVLRRGLQSFCHRLGLCVSRHPVFFLTVPAVLTITFGLSALNRFQTEGDLERLVAPSHSLAKIERSLASSLFPLDQSKSQLYSDLHTPGRYGRVILLSSPGDNILLQAEGILQTHRAVMEMKVNHKGYNYTFSHLCVLRNQDKKCVLDDIISVLEDLRQAAVSNKTTARVQVRYPNTKLKDGRNSFIGHQLGGVVEVPNSKDQRVKSARAIQITYYLQTYGSATQDLIGEKWENEFCKLMRKLQEEHQDLQLYSLASFSLWRDFHKTSILTRSKVLVSLVLILTTATLSSSMKDCLRSKPFLGLLGVLTVCISIATAAGIFFITDGKYNSTLLGIPFFAMGHGTKGVFELLSGWRRTKENLPFKDRVADAYSDVMVTYTMTSSLYFITFGMGASPFTNIEAVKIFCQNMCVSILLNYFYIFSFFGSCLVFAGQLEQNRYHSIFCCKIPSAEYLDRKPVWFQTVMSDGHQQTSHHETNPYQHHFIQHFLREHYNEWITNIYVKPFVVILYLIYASFSFMGCLQISDGASIINLLASDSPSVSYAMVQQKYFSNYSPVIGFYVYEPLEYWNSSVQEDLQRLCSGFTAVSWVEQYYQFLKTSNISANNKTDFISVLQSSFLKKPEFQHFRNDIIFSRAGDENNIIASRLYLVARTSRDKQKEVIEVLDKLRPLSLSKSIRFIVFNPSFVFTDHYSLSVTVPVLIAGFGVLLVLILTFFLVIHPLGNFWLILSVTSIELGVLGLMTLWNVDMDCISILCLIYTLNFAIDHCAPLLYTFVLATEHTRTQCIKSSLQEHGTAILQNITSFLIGLLPLLFVPSNLTFTLFKCLLLTGGCTLLHCFVILPVFLTFFPPSKKHHKKKKRAKRKEREEIECIEIQENPDHVTTV", "length": 904 }, "evidence": [ { "id": "HGNC:21345", "url": "https://alliancegenome.org/gene/HGNC:21345#orthology", "database": "AGR" }, { "id": "RGD:1563020", "url": "https://alliancegenome.org/gene/RGD:1563020#orthology", "database": "AGR" }, { "id": "MGI:1920485", "url": "https://alliancegenome.org/gene/MGI:1920485#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-178", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-178#orthology", "database": "AGR" }, { "id": "Q5RIV7", "url": "https://omabrowser.org/oma/group/Q5RIV7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZRK8-1", "protein_name": "Patched domain containing 4", "gene_name": "Ptchd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRPGAPASWIWWRMLRQVLRRGLQSFCHRLGLCVSRHPVFFLTVPAVLTITFGLSALNRFQTESDLERLVAPSHSLAKIERSLASSLFPLDQSKSQLYSDLHTPGRYGRVILLSPPGDNILLQAEGILQTHRAVMEMKVNHKGYNYTFSHLCVLRNQDKKCVLDDIISVLEDLRQAAVSNKTTARVQVRYPNTKLKDGRNSFIGHQLGGVVEVPNSKDQRVKSARAIQITYYLQTYGSATQDLIGEKWENEFCQLMRKLQDEHQDLQLYSLASFSLWRDFHKTSILTRSKVLVSLVLILTTATLSSSMKDCLRSKPFLGLLGVLTVCISIATAAGIFFITDGKYNSTLLGIPFFAMGHGTKGVFELLSGWRRTKENLPFKDRVADAYSDVMVTYTMTSSLYFITFGMGASPFTNIEAVKIFCQNMCVSILLNYFYIFSFFGSCLVFAGQLEQNRYHSIFCCKIPSAEYLDGKPVWFQTVMSDGHQQTSHHETNPYQHHFIQHFLREHYNEWITNIYVKPFVVILYLIYASFSFMGCLQISDGASIINLLASDSPSVSYAMVQQKYFSNYSPVIGFYVYEPLEYWNSSVQEDLQRLCSGFTAVSWVEQYYQFLKASNISANNKTDFISVLQSSFLKKPEFQHFRNDIIFSRAGDENNIIASRLYLVARTSRDKQKEVIEVLDKLRPLSLSKSIRFIVFNPSFVFTDHNSLSVTVPVLIAGFGVLLVLVLTFFLVIHPLGNFWLILSVTSIELGVLGLMTLWNVDMDCISILCLIYTLNFAIDHCAPLLYTFVLATEHTRTQCIKSSLQEHGTAILQNITSFLIGLVPLLFVPSNLTFTLFKCLLLTGGCTLLHCFVILPVFLTFFPPSKKHHKKKKRAKRKEREEIECIEIQENPDHVTTV", "length": 901 }, "evidence": [ { "id": "HGNC:21345", "url": "https://alliancegenome.org/gene/HGNC:21345#orthology", "database": "AGR" }, { "id": "RGD:1563020", "url": "https://alliancegenome.org/gene/RGD:1563020#orthology", "database": "AGR" }, { "id": "MGI:1920485", "url": "https://alliancegenome.org/gene/MGI:1920485#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-178", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-178#orthology", "database": "AGR" }, { "id": "Q5RIV7", "url": "https://omabrowser.org/oma/group/Q5RIV7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZW05-1", "protein_name": "Patched domain-containing protein 4", "gene_name": "PTCHD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCFLRRPGAPASWIWWRMLRQVLRRGLQSFCHRLGLCVSRHPVFFLTVPAVLTITFGLSALNRFQPEGDLERLVAPSHSLAKIERSLASSLFPLDQSKSQLYSDLHTPGRYGRVILLSPTGDNILLQAEGILQTHRAVLEMKDGRNSFIGHQLGGVVEVPNSKDQRVKSARAIQITYYLQTYGSATQDLIGEKWENEFCKLIRKLQEEHQELQLYSLASFSLWRDFHKTSILARSKVLVSLVLILTTATLSSSMKDCLRSKPFLGLLGVLTVCISIITAAGIFFITDGKYNSTLLGIPFFAMGHGTKGVFELLSGWRRTKENLPFKDRIADAYSDVMVTYTMTSSLYFITFGMGASPFTNIEAVKVFCQNMCVSILLNYFYIFSFFGSCLVFAGQLEQNRYHSIFCCKIPSAEYLDRKPVWFQTVMSDGHQQTSHHETNPYQHHFIQHFLREHYNEWITNIYVKPFVVILYLIYASFSFMGCLQISDGANIINLLASDSPSVSYAMVQQKYFSNYSPVIGFYVYEPLEYWNSSVQDDLRRLCSGFTAVSWVEQYYQFLKVSNVSANNKSDFISVLQSSFLKKPEFQHFRNDIIFSKAGDESNIIASRLYLVARTSRDKQKEITEVLEKLRPLSLSKSIRFIVFNPSFVFMDHYSLSVTVPVLIAGFGVLLVLILTFFLVIHPLGNFWLILSVTSIELGVLGLMTLWNVDMDCISILCLIYTLNFAIDHCAPLLFTFVLATEHTRTQCIKSSLQDHGTAILQNVTSFLIGLVPLLFVPSNLTFTLFKCLLLTGGCTLLHCFVILPVFLTFFPPSKKHHKKKKRAKRKEREEIECIEIQENPDHVTTV", "length": 846 }, "evidence": [ { "id": "HGNC:21345", "url": "https://alliancegenome.org/gene/HGNC:21345#orthology", "database": "AGR" }, { "id": "RGD:1563020", "url": "https://alliancegenome.org/gene/RGD:1563020#orthology", "database": "AGR" }, { "id": "MGI:1920485", "url": "https://alliancegenome.org/gene/MGI:1920485#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-178", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-178#orthology", "database": "AGR" }, { "id": "Q5RIV7", "url": "https://omabrowser.org/oma/group/Q5RIV7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5RIV7", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5RIV7", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7" } ], "pmid": "" }, { "name": "dendritic spine", "id": "GO:0043197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043197", "evidence": [ { "database": "UniProtKB", "id": "Q5RIV7", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 803, "end_pos": 805, "annotation": "n_glycosylation_sequon" }, { "start_pos": 820, "end_pos": 822, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5RIV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIV7" }, { "id": "PRU00199", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00199" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SSD", "eco_id": "ECO_0000255", "start_pos": 273, "end_pos": 433, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "Asn332" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [ 132, 167, 179, 332, 572, 603, 803 ], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 603, "end_pos": 605 }, { "start_pos": 803, "end_pos": 805 }, { "start_pos": 820, "end_pos": 822 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 7 }, { "field": "n_linked_sites", "count": 7 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 7 }, { "field": "exact_n_linked_sites", "count": 7 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 7 }, { "field": "total_sites", "count": 7 }, { "field": "n_linked_sites", "count": 7 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 7 }, { "field": "exact_n_linked_sites", "count": 7 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5RIX6-1", "uniprot_ac": "Q5RIX6", "uniprot_id": "Q5RIX6_DANRE", "mass": { "chemical_mass": 34447.0, "monoisotopic_mass": 34447.0 }, "refseq": { "ac": "NP_001003490", "name": "tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003490" }, "gene_names": [ { "name": "dus4l", "type": "recommended", "evidence": [ { "id": "Q5RIX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6" } ] }, { "name": "dus4l", "type": "synonym", "evidence": [ { "id": "NP_001003490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003490" } ] }, { "name": "zgc:92033", "type": "synonym", "evidence": [ { "id": "NP_001003490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003490" }, { "id": "Q5RIX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6" } ] } ], "protein_names": [ { "name": "tRNA-dihydrouridine synthase", "type": "recommended", "evidence": [ { "id": "Q5RIX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6/entry#names_and_taxonomy" } ] }, { "name": "1.3.1.-", "type": "synonym", "evidence": [ { "id": "Q5RIX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6/entry#names_and_taxonomy" } ] }, { "name": "tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like", "type": "synonym", "evidence": [ { "id": "NP_001003490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003490" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC078413.1, SRR26395017.969818.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Sep 17, 2011 this sequence version replaced NP_001003490.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001003490", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003490" } ] }, { "annotation": "Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs.", "evidence": [ { "database": "UniProtKB", "id": "Q5RIX6", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6#function" }, { "database": "UniProtKB", "id": "PIRNR006621", "url": "https://www.uniprot.org/uniprotkb/PIRNR006621#function" }, { "database": "UniProtKB", "id": "ARBA00002468", "url": "https://www.uniprot.org/uniprotkb/ARBA00002468#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RIX6", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dus4l", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040801-233", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-233", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000006567", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000006567", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02801", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02801", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "445096", "url": "https://www.ncbi.nlm.nih.gov/gene/445096", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018517", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018517", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:445096", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:445096", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QRPHHDI", "url": "https://omabrowser.org/oma/group/QRPHHDI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5RIX6", "url": "https://www.orthodb.org/?gene=Q5RIX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11082:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11082:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001003490", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003490", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "53344", "url": "https://www.rhea-db.org/rhea/53344", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53348", "url": "https://www.rhea-db.org/rhea/53348", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53352", "url": "https://www.rhea-db.org/rhea/53352", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53356", "url": "https://www.rhea-db.org/rhea/53356", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5RIX6", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RIX6-1", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040801-233", "url": "https://zfin.org/ZDB-GENE-040801-233", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMDRGNVMDLFSREKPVRVCAPMVRYSKLAFRTLVRKYDCDVCFTPMIIAADFMRSAKARDSEFTTNKNDRPLIVQFAAKDAQTLADAACVVSPFSDGVDLNCGCPQRWAMSEGYGACLINKPELVKDMVRHVRNQIDNPNYAVSIKIRIHKDVRQTVDLCQKVEAAGVSYITVHGRTAIERHQPVHYDTIKTIKDSLSIPVIANGDIKSMQDVEAVCELTGVDGVMSARGLLSNPAMFSGFEETPLQCVWDWVDIAAEHGTPFTCFHHHLIHMLERITSQPERRVFNNLSSTSAVIDFLHNTYGSM", "length": 307, "header": "tr|Q5RIX6-1|Q5RIX6_DANRE Isoform 1 of tRNA-dihydrouridine synthase OS=Danio rerio OX=7955 GN=dus4l PE=3 SV=1 CANONICAL=Q5RIX6-1" }, "isoforms": [ { "isoform_ac": "Q5RIX6-1", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6/entry#Q5RIX6-1", "sequence": { "sequence": "MMDRGNVMDLFSREKPVRVCAPMVRYSKLAFRTLVRKYDCDVCFTPMIIAADFMRSAKARDSEFTTNKNDRPLIVQFAAKDAQTLADAACVVSPFSDGVDLNCGCPQRWAMSEGYGACLINKPELVKDMVRHVRNQIDNPNYAVSIKIRIHKDVRQTVDLCQKVEAAGVSYITVHGRTAIERHQPVHYDTIKTIKDSLSIPVIANGDIKSMQDVEAVCELTGVDGVMSARGLLSNPAMFSGFEETPLQCVWDWVDIAAEHGTPFTCFHHHLIHMLERITSQPERRVFNNLSSTSAVIDFLHNTYGSM", "length": 307, "header": "tr|Q5RIX6-1|Q5RIX6_DANRE Isoform 1 of tRNA-dihydrouridine synthase OS=Danio rerio OX=7955 GN=dus4l PE=3 SV=1 CANONICAL=Q5RIX6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "Q5RIX6", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "Q5RIX6", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:445096", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:445096", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061HZ21-1", "protein_name": "tRNA-dihydrouridine synthase", "gene_name": "Dus4l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRSDSIPITICQERKKDPMEMFQSGQMVKICAPMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVRSIKARDSEFTTNQGDCPLIVQFAANDARILSDAAQIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVRNQVENPRFSVSIKIRIHDDLTRTIDLCQKAEATGVSWITVHGRTIEERHQPVHYEAIKIIKESVSIPVVANGDIRNLKEAENVWQMSGTDGVMVARGLLANPAMFAGYEETPLKCIWDWVDIALELGTPFMCFHQHLMYMMEKITSRQEKRVFNALSSTSAVLEYLTDNYGV", "length": 317 }, "evidence": [ { "id": "Q5RIX6", "url": "https://omabrowser.org/oma/group/Q5RIX6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A0G2K3I5-1", "protein_name": "tRNA-dihydrouridine synthase", "gene_name": "Dus4l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSDSIPTTICQERKKDPVEMFHSGQLVKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVRSVKARDSEFTTNQGDCPLIVQFAANDARLLSDAALIVCPYASGIDINCGCPQRWAMADGYGACLINKPELVLDMVRQVRNRVENPRFSVSIKIRIHDDLARTIDLCRKVEATGVSWITVHGRTVEERHQPVHYDAIKMIKENVSIPIVANGDIRSLKEAENVWQMTGTDGVMVARGLLANPAMFAGYEETPLKCVWDWVDIALELGTPFMCFHQHLMYMMEKITSRQEKRVFNALSSTSAVLDYLTDHYGDDSTF", "length": 321 }, "evidence": [ { "id": "HGNC:21517", "url": "https://alliancegenome.org/gene/HGNC:21517#orthology", "database": "AGR" }, { "id": "MGI:1919166", "url": "https://alliancegenome.org/gene/MGI:1919166#orthology", "database": "AGR" }, { "id": "Q5RIX6", "url": "https://omabrowser.org/oma/group/Q5RIX6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XWI8-1", "protein_name": "tRNA-dihydrouridine synthase", "gene_name": "DUS4L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCVTSCRGLARLTDTCVPLSGTHLPSGAAGSTRAAPLRLAFRTLVRRYGCDLCYTPMVVAADFVRSAKARDSEFTTNRGDNPLIVQFAAKEAQVLCDAALLVCPFADGVDLNCGCPQRWAMAEGYGACLINKPELVRDMVRHVRNQIDNPRFSVSIKIRIHEDLKKTVDLCKKAEATGVSWITVHGRNIEERHQPVHYDAIKVIKESIHIPVVANGDIKTLKDAENVHHLTGADGVMVARGLLANPAMFAGYEETPLKCIQDWVDIALEHGTPFTCFHHHLMYMMERITSKQEKKVFNILSSTSAVLDYLGHHYGVCS", "length": 318 }, "evidence": [ { "id": "Q5RIX6", "url": "https://omabrowser.org/oma/group/Q5RIX6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O95620-1", "protein_name": "tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like", "gene_name": "DUS4L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSDCMQTTICQERKKDPIEMFHSGQLVKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIVAADFVKSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAARIVCPYANGIDINCGCPQRWAMAEGYGACLINKPELVQDMVKQVRNQVETPGFSVSIKIRIHDDLKRTVDLCQKAEATGVSWITVHGRTAEERHQPVHYDSIKIIKENMSIPVIANGDIRSLKEAENVWRITGTDGVMVARGLLANPAMFAGYEETPLKCIWDWVDIALELGTPYMCFHQHLMYMMEKITSRQEKRVFNALSSTSAIIDYLTDHYGI", "length": 317 }, "evidence": [ { "id": "HGNC:21517", "url": "https://alliancegenome.org/gene/HGNC:21517#orthology", "database": "AGR" }, { "id": "MGI:1919166", "url": "https://alliancegenome.org/gene/MGI:1919166#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-233", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-233#orthology", "database": "AGR" }, { "id": "Q5RIX6", "url": "https://omabrowser.org/oma/group/Q5RIX6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q06063-1", "protein_name": "tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]", "gene_name": "DUS4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHTMHIPSGDVLIPKPKLITEETDPLHIIKTRQKTHGRPVTIAGPMVRYSKLPFRQLCREYNVDIVYSPMILAREYVRNEHARISDLSTNNEDTPLIVQVGVNNVADLLKFVEMVAPYCDGIGINCGCPIKEQIREGIGCALIYNSDLLCSMVHAVKDKYGDKLRIETKIRIHEALDETVELCRKLCDAGVDWITIHGRTRRTRSSQPANLDAIKYIIENISDKNVPVIANGDCFKLSDLERITKYTGAHGVMAVRGLLSNPALFAGYTTCPWGCIEKFCYWALEFGGLPFQLAQHHLYCMLENMELKKSLLKKMMNLKNYISLIDWFNKTFEFKRYGEDGFGMGVEIPYKANSCVQRSASVVERQE", "length": 367 }, "evidence": [ { "id": "HGNC:21517", "url": "https://alliancegenome.org/gene/HGNC:21517#orthology", "database": "AGR" }, { "id": "MGI:1919166", "url": "https://alliancegenome.org/gene/MGI:1919166#orthology", "database": "AGR" }, { "id": "Q5RIX6", "url": "https://omabrowser.org/oma/group/Q5RIX6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q32KL9-1", "protein_name": "B-cell receptor-associated protein 29", "gene_name": "BCAP29", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTLQWTAVATFLYAEIGLILIFCLPFIPPQRWQKIFSFSVWGKIASFWNKAFLTIIILLIVLFLDAVREVRKYSSTHTIEKSSASRPAAYEHTQMKLFRSQRNLYISGFSLFFWLVLRRLVTLITQLAKELSHKGVLKHQAENINQAAKKFMEENERLKRLLKNYGKEEEHILEAENKKLEEDKEKLKTELKKASDALSKAQNDVMIMKMQSERLSKEYDRLLREHSELQDRAGKDKKCL", "length": 240 }, "evidence": [ { "id": "Q5RIX6", "url": "https://omabrowser.org/oma/group/Q5RIX6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q32M08-1", "protein_name": "tRNA-dihydrouridine(20a/20b) synthase [NAD(P)+]-like", "gene_name": "Dus4l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSDSLPTTICQERKKDPIEMFHSGQLVKVCAPMVRYSKLAFRTLVRKYSCDLCYTPMIIAADFVRSIKARDSEFTTNQGDCPLIVQFAANDARLLSDAALLVCPYANGIDINCGCPQRWAMADGYGACLINKPELVHDMVRQVRNRVESPRFSVSIKIRIHDDLARTIDLCRKAEATGVSWITVHGRTVEERHQPVHYDAIKMIKENVSIPIVANGDIRSLKEAENVWQMTGTDGVMVARGLLANPAMFAGYEETPLKCIWDWVDISLELGTPFMCFHQHLMYMMEKITSRQEKRVFNALSSTSAVLDYLTDHYGDESLSKSL", "length": 324 }, "evidence": [ { "id": "HGNC:21517", "url": "https://alliancegenome.org/gene/HGNC:21517#orthology", "database": "AGR" }, { "id": "MGI:1919166", "url": "https://alliancegenome.org/gene/MGI:1919166#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-233", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-233#orthology", "database": "AGR" }, { "id": "Q5RIX6", "url": "https://omabrowser.org/oma/group/Q5RIX6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54XQ6-1", "protein_name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]", "gene_name": "dus1l", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSISSSEILDSSKNYNPDEEEEIEEKKDNIIMNPVISKLGGYEFFRNVLKSPKKTVAPMVDHTFLAFRMLCRKYGADMVYTPMFHSKNFATCKTYRRDYWSTCPEDRPLVVQFCGNEPEWVVKAAKYIEDHCDAIDLNLGCPQQIARRGNYGSFLLDKPHIILPIVQELHKHIKVPIFCKIRLLPNLDDTIKLALQLQEAGCQLLTIHGRTKEQKGHNSGIANWKAIRTIREQLSIPVIANGSVVQYEDIDRCLEETGADGVMSAEGILANPSFFSGLKVPIYQVAREYIDFTEIYKTSIHVTRSHIFKMLKEKLDVYSDLRETMGATHTNDGFRDIITDLETREKNNLPPVKILTNKQKRELKQKENNDIDSLKKQKLDDNNNNENNNNNNNNNNNNNNNNNNNNINENNNNNNNNTEIKNEDEKEKVLINNSN", "length": 435 }, "evidence": [ { "id": "Q5RIX6", "url": "https://omabrowser.org/oma/group/Q5RIX6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9VJ06-1", "protein_name": "1.3.1.90", "gene_name": "Dus4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHLPQQRPHHDIAAMFAEAQSDFVRVSAPMVRYSKLEFRRLVRLNGVQLAFTPMMISDSINNSEKARQNEFSTGADDQPLIAQFAAKDPTEFVTSAQLIYPYVDGIDLNCGCPQSWAMAKGYGCGMLRQPELVHQVVQEVRRTLPGDFSVSVKMRLLGGEESLQRTIDLARQLESAGVTFLTLHGRTPAQKHSKDTLDIPAMSQVRQSLQIPLIVNGNVESYRDACDMHEQTGAAGVMAARGLLANPALFNSNYPDGKTTPLSCVQQWLDIASAAGDNLLFQCFHHHLTFMYSAQMKRDLRVQFNSLGSKEQVVDFLKEHYNLEYSEVDPPSADYTDCTYTHFTPPKHARHIAAESDEQAWSSKSDGKFFTVFRAHQLTGTGGEDLELGGLFGDEE", "length": 396 }, "evidence": [ { "id": "HGNC:21517", "url": "https://alliancegenome.org/gene/HGNC:21517#orthology", "database": "AGR" }, { "id": "MGI:1919166", "url": "https://alliancegenome.org/gene/MGI:1919166#orthology", "database": "AGR" }, { "id": "Q5RIX6", "url": "https://omabrowser.org/oma/group/Q5RIX6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "flavin adenine dinucleotide binding", "id": "GO:0050660", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050660", "evidence": [ { "database": "UniProtKB", "id": "Q5RIX6", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6" } ], "pmid": "" }, { "name": "tRNA dihydrouridine synthase activity", "id": "GO:0017150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017150", "evidence": [ { "database": "UniProtKB", "id": "Q5RIX6", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6" } ], "pmid": "" }, { "name": "tRNA-dihydrouridine20a synthase activity", "id": "GO:0102266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0102266", "evidence": [ { "database": "UniProtKB", "id": "Q5RIX6", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "53344", "name": "", "equation": "5,6-dihydrouridine(20a) in tRNA + NADP(+) = uridine(20a) in tRNA + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5RIX6-1" ], "evidence": [ { "id": "53344", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53344" } ] }, { "id": "53348", "name": "", "equation": "5,6-dihydrouridine(20a) in tRNA + NAD(+) = uridine(20a) in tRNA + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5RIX6-1" ], "evidence": [ { "id": "53348", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53348" } ] }, { "id": "53352", "name": "", "equation": "5,6-dihydrouridine(20b) in tRNA + NAD(+) = uridine(20b) in tRNA + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5RIX6-1" ], "evidence": [ { "id": "53352", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53352" } ] }, { "id": "53356", "name": "", "equation": "5,6-dihydrouridine(20b) in tRNA + NADP(+) = uridine(20b) in tRNA + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5RIX6-1" ], "evidence": [ { "id": "53356", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53356" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "Q5RIX6", "gene_name": "dus4l", "activity": [ { "ec_number": "1.3.1.-", "activity": "", "evidence": [ { "id": "Q5RIX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5RIX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RIX6" }, { "id": "PF01207", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01207" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUS-like FMN-binding", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 280, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 289, "end_pos": 291 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5RKN3-1", "uniprot_ac": "Q5RKN3", "uniprot_id": "MED28_DANRE", "mass": { "chemical_mass": 19697.0, "monoisotopic_mass": 19697.0 }, "refseq": { "ac": "NP_001007771", "name": "mediator of RNA polymerase II transcription subunit 28", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007771" }, "gene_names": [ { "name": "med28", "type": "recommended", "evidence": [ { "id": "Q5RKN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3" } ] }, { "name": "med28", "type": "synonym", "evidence": [ { "id": "NP_001007771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007771" } ] }, { "name": "wu:fc74b11", "type": "synonym", "evidence": [ { "id": "NP_001007771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007771" }, { "id": "Q5RKN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3" } ] }, { "name": "zgc:103633", "type": "synonym", "evidence": [ { "id": "NP_001007771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007771" }, { "id": "Q5RKN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3" } ] } ], "protein_names": [ { "name": "Mediator of RNA polymerase II transcription subunit 28", "type": "recommended", "evidence": [ { "id": "Q5RKN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3/entry#names_and_taxonomy" } ] }, { "name": "Mediator complex subunit 28", "type": "synonym", "evidence": [ { "id": "Q5RKN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3/entry#names_and_taxonomy" } ] }, { "name": "mediator of RNA polymerase II transcription subunit 28", "type": "synonym", "evidence": [ { "id": "NP_001007771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007771" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC085569.1, EH536493.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085569.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007771", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007771" } ] }, { "annotation": "Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5RKN3", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RKN3", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "med28", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041121-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041121-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5RKN3", "url": "https://alphafold.ebi.ac.uk/entry/Q5RKN3", "database": "AlphaFoldDB", "categories": [] }, { "id": "493610", "url": "https://www.ncbi.nlm.nih.gov/gene/493610", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021640", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021640", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:493610", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:493610", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5RKN3", "url": "https://www.orthodb.org/?gene=Q5RKN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13512", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13512", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13512:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13512:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11594", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11594", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5RKN3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5RKN3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007771", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007771", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58IZT9", "url": "https://www.uniprot.org/uniprotkb/A0AC58IZT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IZT9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IZT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RKN3", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RKN3-1", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041121-4", "url": "https://zfin.org/ZDB-GENE-041121-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASSMCGMFPGQQPPGSLPPPGPGGPGQPGLLTGTPGNRGANNTLVDELEASFEACFASLVSQDYVNGTDQEEIRTGVDQCIQKFLDVARQTECFFLQKRLQLSVQKPEQVEKEDASELKNELQRKEMLIQKHLAKIHHWQQVLEDINVQHKKPTELPQGPLAFLEQASANLPAPMKPN", "length": 179, "header": "sp|Q5RKN3-1|MED28_DANRE Isoform 1 of Mediator of RNA polymerase II transcription subunit 28 OS=Danio rerio OX=7955 GN=med28 PE=2 SV=1 CANONICAL=Q5RKN3-1" }, "isoforms": [ { "isoform_ac": "A0AC58IZT9-1", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3/entry#A0AC58IZT9-1", "sequence": { "sequence": "MASSMGGMFPGQQPPGSHPPPGPGGPGQPGLLTGTPGNRGANNTLVDELEASFEGLISVYRSFWMWPDRLNVSFFRRDYSSLYRNQNRWKKRMHQN", "length": 96, "header": "tr|A0AC58IZT9-1|A0AC58IZT9_DANRE Computationally mapped isoform of Mediator of RNA polymerase II transcription subunit 28 isoform X1 OS=Danio rerio OX=7955 GN=med28 PE=4 SV=1 CANONICAL=Q5RKN3-1" }, "locus": {} }, { "isoform_ac": "Q5RKN3-1", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3/entry#Q5RKN3-1", "sequence": { "sequence": "MASSMCGMFPGQQPPGSLPPPGPGGPGQPGLLTGTPGNRGANNTLVDELEASFEACFASLVSQDYVNGTDQEEIRTGVDQCIQKFLDVARQTECFFLQKRLQLSVQKPEQVEKEDASELKNELQRKEMLIQKHLAKIHHWQQVLEDINVQHKKPTELPQGPLAFLEQASANLPAPMKPN", "length": 179, "header": "sp|Q5RKN3-1|MED28_DANRE Isoform 1 of Mediator of RNA polymerase II transcription subunit 28 OS=Danio rerio OX=7955 GN=med28 PE=2 SV=1 CANONICAL=Q5RKN3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:493610", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:493610", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P68943-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 28", "gene_name": "Med28", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASLGGMFAGQPPGPPPPPPGLPGQASLLQAAPGAPRPSNSTLVDELESSFEACFASLVSQDYVNGTDQEEIRTGVDQCIQKFLDIARQTECFFLQKRLQLSVQKPDQVIKEDVSELRSELQRKDALVQKHLTKLRHWQQVLEDINVQHKKPADMPQGSLAYLEQASANIPAPLKQT", "length": 178 }, "evidence": [ { "id": "RGD:1305875", "url": "https://alliancegenome.org/gene/RGD:1305875#orthology", "database": "AGR" }, { "id": "MGI:1914249", "url": "https://alliancegenome.org/gene/MGI:1914249#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041121-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041121-4#orthology", "database": "AGR" }, { "id": "HGNC:24628", "url": "https://alliancegenome.org/gene/HGNC:24628#orthology", "database": "AGR" }, { "id": "FB:FBgn0039337", "url": "https://alliancegenome.org/gene/FB:FBgn0039337#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q920D3-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 28", "gene_name": "Med28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASLGGMFTGQPPGPPPPPPGLPGQASLLQAAPGAPRPSNSTLVDELESSFEACFASLVSQDYVNGTDQEEIRTGVDQCIQKFLDIARQTECFFLQKRLQLSVQKPDQVIKEDVSELRSELQRKDALVQKHLTKLRHWQQVLEDINVQHKKPADMPQGSLAFLEQASANIPAPLKQT", "length": 178 }, "evidence": [ { "id": "RGD:1305875", "url": "https://alliancegenome.org/gene/RGD:1305875#orthology", "database": "AGR" }, { "id": "MGI:1914249", "url": "https://alliancegenome.org/gene/MGI:1914249#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041121-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041121-4#orthology", "database": "AGR" }, { "id": "HGNC:24628", "url": "https://alliancegenome.org/gene/HGNC:24628#orthology", "database": "AGR" }, { "id": "FB:FBgn0039337", "url": "https://alliancegenome.org/gene/FB:FBgn0039337#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H204-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 28", "gene_name": "MED28", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPLGGMFSGQPPGPPQAPPGLPGQASLLQAAPGAPRPSSSTLVDELESSFEACFASLVSQDYVNGTDQEEIRTGVDQCIQKFLDIARQTECFFLQKRLQLSVQKPEQVIKEDVSELRNELQRKDALVQKHLTKLRHWQQVLEDINVQHKKPADIPQGSLAYLEQASANIPAPLKPT", "length": 178 }, "evidence": [ { "id": "RGD:1305875", "url": "https://alliancegenome.org/gene/RGD:1305875#orthology", "database": "AGR" }, { "id": "MGI:1914249", "url": "https://alliancegenome.org/gene/MGI:1914249#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041121-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041121-4#orthology", "database": "AGR" }, { "id": "HGNC:24628", "url": "https://alliancegenome.org/gene/HGNC:24628#orthology", "database": "AGR" }, { "id": "FB:FBgn0039337", "url": "https://alliancegenome.org/gene/FB:FBgn0039337#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VBQ9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 28", "gene_name": "MED28", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASNESGGGNLMDEFEEAFQSCLLTLTKQEPNSGTNKEEIDLEVQKTTNRFIDVARQMEAFFLQKRFLVSTLKPYMLIKDENQDLSIEIQRKEALLQKHYNRLEEWKACLSDIQQGVHSRPTPPIGSGMLQGPGGGMPPMGGTPPRPGMMPGMPPGAMQPGGPMQPSPHMLQAQQMQQLRMISRQMPPK", "length": 189 }, "evidence": [ { "id": "RGD:1305875", "url": "https://alliancegenome.org/gene/RGD:1305875#orthology", "database": "AGR" }, { "id": "MGI:1914249", "url": "https://alliancegenome.org/gene/MGI:1914249#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041121-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041121-4#orthology", "database": "AGR" }, { "id": "HGNC:24628", "url": "https://alliancegenome.org/gene/HGNC:24628#orthology", "database": "AGR" }, { "id": "FB:FBgn0039337", "url": "https://alliancegenome.org/gene/FB:FBgn0039337#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5RKN3", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mediator complex", "id": "GO:0016592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016592", "evidence": [ { "database": "UniProtKB", "id": "Q5RKN3", "url": "https://www.uniprot.org/uniprotkb/Q5RKN3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 42, "end_pos": 44 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q5RKQ0-1", "uniprot_ac": "Q5RKQ0", "uniprot_id": "SPF27_DANRE", "mass": { "chemical_mass": 25863.0, "monoisotopic_mass": 25863.0 }, "refseq": { "ac": "NP_001007775", "name": "pre-mRNA-splicing factor SPF27", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007775" }, "gene_names": [ { "name": "bcas2", "type": "recommended", "evidence": [ { "id": "Q5RKQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0" } ] }, { "name": "bcas2", "type": "synonym", "evidence": [ { "id": "NP_001007775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007775" } ] }, { "name": "cb302", "type": "synonym", "evidence": [ { "id": "NP_001007775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007775" } ] }, { "name": "zgc:101730", "type": "synonym", "evidence": [ { "id": "NP_001007775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007775" }, { "id": "Q5RKQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0" } ] } ], "protein_names": [ { "name": "Pre-mRNA-splicing factor SPF27", "type": "recommended", "evidence": [ { "id": "Q5RKQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0/entry#names_and_taxonomy" } ] }, { "name": "DKEYP-46C9.2", "type": "synonym", "evidence": [ { "id": "NP_001007775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007775" } ] }, { "name": "Protein BCAS2 homolog", "type": "synonym", "evidence": [ { "id": "Q5RKQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0/entry#names_and_taxonomy" } ] }, { "name": "breast carcinoma amplified sequence 2", "type": "synonym", "evidence": [ { "id": "NP_001007775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007775" } ] }, { "name": "pre-mRNA-splicing factor SPF27", "type": "synonym", "evidence": [ { "id": "NP_001007775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007775" } ] }, { "name": "protein BCAS2 homolog", "type": "synonym", "evidence": [ { "id": "NP_001007775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007775" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC085427.1, EH456817.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085427.1. On Jul 6, 2005 this sequence version replaced XP_699586.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007775", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007775" } ] }, { "annotation": "Findings revealed a novel and vital role for BCAS2 during Hematopoietic stem and progenitor cells maintenance in zebrafish.", "evidence": [ { "database": "RefSeq", "id": "NP_001007775", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007775" }, { "database": "PubMed", "id": "30482793", "url": "https://glygen.org/publication/PubMed/30482793" } ] }, { "annotation": "Required for pre-mRNA splicing as component of the activated spliceosome. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex.", "evidence": [ { "database": "UniProtKB", "id": "Q5RKQ0", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0#function" }, { "database": "UniProtKB", "id": "O75934", "url": "https://www.uniprot.org/uniprotkb/O75934#function" } ] } ], "disease": [ { "disease_id": "DOID:1612", "recommended_name": { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland." }, "synonyms": [ { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "breast tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "primary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer susceptibility, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, lobular, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ], "unlinked_id_list": [ "DOID:3017", "DOID:0050938" ], "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5RKQ0", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "bcas2", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030408-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030408-5", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5RKQ0", "url": "https://alphafold.ebi.ac.uk/entry/Q5RKQ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000043631", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000043631", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "493614", "url": "https://www.ncbi.nlm.nih.gov/gene/493614", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:493614", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:493614", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SAWQESI", "url": "https://omabrowser.org/oma/group/SAWQESI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5RKQ0", "url": "https://www.orthodb.org/?gene=Q5RKQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13296", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13296", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13296:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13296:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05700", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05700", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5RKQ0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5RKQ0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DRE-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001007775", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007775", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5RKQ0", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5RKQ0-1", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030408-5", "url": "https://zfin.org/ZDB-GENE-030408-5", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAGPASVAGDVFVDALPYFDQGYDATGVREAAAALVEEETRRYRPTKNYLSYLPTPDFSAFETEIMRNEFERLAARQPMELLSMKRYELPAPSSGQKNDMTAWQDCVNNSMAQLEHQAVRIENLELMAQYGTNAWKMSNDNLALMIENSQKELQNVRKEIQDLNWQRKNDQLAGGAKLRELESNWVSLVSKNYEIERAIVQLENEVAQMKQQQGDENKENIRQDF", "length": 225, "header": "sp|Q5RKQ0-1|SPF27_DANRE Isoform 1 of Pre-mRNA-splicing factor SPF27 OS=Danio rerio OX=7955 GN=bcas2 PE=2 SV=1 CANONICAL=Q5RKQ0-1" }, "isoforms": [ { "isoform_ac": "Q5RKQ0-1", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0/entry#Q5RKQ0-1", "sequence": { "sequence": "MAGPASVAGDVFVDALPYFDQGYDATGVREAAAALVEEETRRYRPTKNYLSYLPTPDFSAFETEIMRNEFERLAARQPMELLSMKRYELPAPSSGQKNDMTAWQDCVNNSMAQLEHQAVRIENLELMAQYGTNAWKMSNDNLALMIENSQKELQNVRKEIQDLNWQRKNDQLAGGAKLRELESNWVSLVSKNYEIERAIVQLENEVAQMKQQQGDENKENIRQDF", "length": 225, "header": "sp|Q5RKQ0-1|SPF27_DANRE Isoform 1 of Pre-mRNA-splicing factor SPF27 OS=Danio rerio OX=7955 GN=bcas2 PE=2 SV=1 CANONICAL=Q5RKQ0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "BCAS2 is essential for hematopoietic stem and progenitor cell maintenance during zebrafish embryogenesis.", "journal": "Blood", "date": "2019-02-21", "authors": "Yu Shanshan, Jiang Tao, Jia Danna, Han Yunqiao, Liu Fei, Huang Yuwen, Qu Zhen, Zhao Yuntong, Tu Jiayi, Lv Yuexia, Li Jingzhen, Hu Xuebin, Lu Zhaojing, Han Shanshan, Qin Yayun, Liu Xiliang, Xie Shanglun, Wang Qing K, Tang Zhaohui, Luo Daji, Liu Mugen", "evidence": [ { "database": "RefSeq", "id": "NP_001007775", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007775" } ], "reference": [ { "type": "PubMed", "id": "30482793", "url": "https://glygen.org/publication/PubMed/30482793" } ] } ], "pathway": [ { "id": "dre:493614", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:493614", "resource": "KEGG Pathway" }, { "id": "R-DRE-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IM09-1", "protein_name": "Pre-mRNA-splicing factor SPF27", "gene_name": "Bcas2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLSAGSKLREMESNWVSLVSKNYEIERTIVQLENEICQIKQQHGEANKENIRQDF", "length": 225 }, "evidence": [ { "id": "Q5RKQ0", "url": "https://omabrowser.org/oma/group/Q5RKQ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "B5DFM8-1", "protein_name": "Pre-mRNA-splicing factor SPF27", "gene_name": "Bcas2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQDCVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGAKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF", "length": 225 }, "evidence": [ { "id": "RGD:1306485", "url": "https://alliancegenome.org/gene/RGD:1306485#orthology", "database": "AGR" }, { "id": "MGI:1915433", "url": "https://alliancegenome.org/gene/MGI:1915433#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030408-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030408-5#orthology", "database": "AGR" }, { "id": "HGNC:975", "url": "https://alliancegenome.org/gene/HGNC:975#orthology", "database": "AGR" }, { "id": "FB:FBgn0039558", "url": "https://alliancegenome.org/gene/FB:FBgn0039558#orthology", "database": "AGR" }, { "id": "Q5RKQ0", "url": "https://omabrowser.org/oma/group/Q5RKQ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I6L631-1", "protein_name": "Pre-mRNA-splicing factor SPF27", "gene_name": "BCAS2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESTWVSLVSKNYEIERTIVQLENELFQMKQQHGEANKENIRQDF", "length": 225 }, "evidence": [ { "id": "Q5RKQ0", "url": "https://omabrowser.org/oma/group/Q5RKQ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O75934-1", "protein_name": "Pre-mRNA-splicing factor SPF27", "gene_name": "BCAS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF", "length": 225 }, "evidence": [ { "id": "RGD:1306485", "url": "https://alliancegenome.org/gene/RGD:1306485#orthology", "database": "AGR" }, { "id": "MGI:1915433", "url": "https://alliancegenome.org/gene/MGI:1915433#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030408-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030408-5#orthology", "database": "AGR" }, { "id": "HGNC:975", "url": "https://alliancegenome.org/gene/HGNC:975#orthology", "database": "AGR" }, { "id": "FB:FBgn0039558", "url": "https://alliancegenome.org/gene/FB:FBgn0039558#orthology", "database": "AGR" }, { "id": "Q5RKQ0", "url": "https://omabrowser.org/oma/group/Q5RKQ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54SG7-1", "protein_name": "Pre-mRNA-splicing factor spf27", "gene_name": "spf27", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNIIIEGAENIDSLPYVDDSVNENEQELINKLISDEMSTFTPPDYLAQLPSFIDIDYNNFQFLENDFKRMEKEEKMKEFDIGRYKVEPTTTMIKQQLNEKQWNDSLNNARSQLEHQDIRKINLELLQRYGGNSWKLYLSDLEILQKTLKKQLDQKKQQIEEINIQRKLSQEQTFEKIQQHDKKFLELVYKNTEIESACKSIELEIEQLKLKQQLQQQQENGDLNNK", "length": 226 }, "evidence": [ { "id": "Q5RKQ0", "url": "https://omabrowser.org/oma/group/Q5RKQ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q949S9-1", "protein_name": "Pre-mRNA-splicing factor SPF27 homolog", "gene_name": "MOS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATNNGDVLMLEATPEAARPWASAANAEVIDALPYIDDDYGNPLIKSEVDRLVEEEMRRSSKKPADFLKDLPPLPKFDFKNCPVLGKEYERVRAGKPPVRIDFESRYKLEMPPANKRNDDAAWKQYLQKNQRSLQQKLIELENLELMSKLGPELWRQNNHRLEVFLTRMQRLAQEQNEEIEKVNRERKYHQQTTSYELNALSQEWRQLCVKNMEIQSACAMLETQIDSFKKEAAERGWNLEEKLENVEPLQMQ", "length": 253 }, "evidence": [ { "id": "Q5RKQ0", "url": "https://omabrowser.org/oma/group/Q5RKQ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9D287-1", "protein_name": "Pre-mRNA-splicing factor SPF27", "gene_name": "Bcas2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGTGLVAGEVVVDALPYFDQGYEAPGVREAAAALVEEETRRYRPTKNYLSYLTAPDYSAFETDIMRNEFERLAARQPIELLSMKRYELPAPSSGQKNDITAWQECVNNSMAQLEHQAVRIENLELMSQHGCNAWKVYNENLVHMIEHAQKELQKLRKHIQDLNWQRKNMQLTAGSKLREMESNWVSLVSKNYEIERTIVQLENEIYQIKQQHGEANKENIRQDF", "length": 225 }, "evidence": [ { "id": "RGD:1306485", "url": "https://alliancegenome.org/gene/RGD:1306485#orthology", "database": "AGR" }, { "id": "MGI:1915433", "url": "https://alliancegenome.org/gene/MGI:1915433#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030408-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030408-5#orthology", "database": "AGR" }, { "id": "HGNC:975", "url": "https://alliancegenome.org/gene/HGNC:975#orthology", "database": "AGR" }, { "id": "FB:FBgn0039558", "url": "https://alliancegenome.org/gene/FB:FBgn0039558#orthology", "database": "AGR" }, { "id": "Q5RKQ0", "url": "https://omabrowser.org/oma/group/Q5RKQ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VAY6-1", "protein_name": "Pre-mRNA-splicing factor SPF27", "gene_name": "BCAS2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAGEVIVDALPYIDHGYDDVGVRESALAMVEEECRRYRPTKNYLDHLPLPASSPFETPLMANEFERIQNRLPMETLSMKRYELPPPPSGKLSEVSAWQEAIENSMAQLEHQWVRSLNLELMLDYGTEAWKSYLEVFTAMQAKAQLQLQQLKKDIQDVNWQRKQAQTQAGERLRSLEAHWVLLVSKNYEIETECVELEKIVHAARQQLRKITPPPSANDTAPTPEYTNGFDQNDLAESNGSSSSNPDPSQPGDDGTDADGDSKEEDKSEAQEESSNGST", "length": 278 }, "evidence": [ { "id": "RGD:1306485", "url": "https://alliancegenome.org/gene/RGD:1306485#orthology", "database": "AGR" }, { "id": "MGI:1915433", "url": "https://alliancegenome.org/gene/MGI:1915433#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030408-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030408-5#orthology", "database": "AGR" }, { "id": "HGNC:975", "url": "https://alliancegenome.org/gene/HGNC:975#orthology", "database": "AGR" }, { "id": "FB:FBgn0039558", "url": "https://alliancegenome.org/gene/FB:FBgn0039558#orthology", "database": "AGR" }, { "id": "Q5RKQ0", "url": "https://omabrowser.org/oma/group/Q5RKQ0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5RKQ0", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0" } ], "pmid": "" }, { "name": "catalytic step 2 spliceosome", "id": "GO:0071013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071013", "evidence": [ { "database": "UniProtKB", "id": "Q5RKQ0", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0" } ], "pmid": "" }, { "name": "U2-type catalytic step 2 spliceosome", "id": "GO:0071007", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071007", "evidence": [ { "database": "UniProtKB", "id": "Q5RKQ0", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0" } ], "pmid": "" }, { "name": "Prp19 complex", "id": "GO:0000974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000974", "evidence": [ { "database": "UniProtKB", "id": "Q5RKQ0", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mRNA splicing, via spliceosome", "id": "GO:0000398", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000398", "evidence": [ { "database": "UniProtKB", "id": "Q5RKQ0", "url": "https://www.uniprot.org/uniprotkb/Q5RKQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 55 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5SNQ6-1", "uniprot_ac": "Q5SNQ6", "uniprot_id": "Q5SNQ6_DANRE", "mass": { "chemical_mass": 8080.0, "monoisotopic_mass": 8080.0 }, "refseq": { "ac": "NP_001127834", "name": "general transcription factor IIH subunit 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127834" }, "gene_names": [ { "name": "gtf2h5", "type": "recommended", "evidence": [ { "id": "Q5SNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ6" } ] }, { "name": "gtf2h5", "type": "synonym", "evidence": [ { "id": "NP_001127834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127834" } ] }, { "name": "si:dkey-12h9.4", "type": "synonym", "evidence": [ { "id": "NP_001127834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127834" }, { "id": "Q5SNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ6" } ] }, { "name": "zgc:153434", "type": "synonym", "evidence": [ { "id": "NP_001127834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127834" }, { "id": "Q5SNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ6" } ] } ], "protein_names": [ { "name": "General transcription and DNA repair factor IIH subunit TFB5", "type": "recommended", "evidence": [ { "id": "Q5SNQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ6/entry#names_and_taxonomy" } ] }, { "name": "general transcription factor IIH subunit 5", "type": "synonym", "evidence": [ { "id": "NP_001127834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127834" } ] }, { "name": "ttda", "type": "synonym", "evidence": [ { "id": "NP_001127834", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127834" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01007106.1, CT645355.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476732, SAMEA4476783 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1, EH536442.1 and BI709501.1. On Jul 29, 2011 this sequence version replaced NP_001127834.1. Transcript Variant: This variant (1) represents the longest transcript. Variants 1, 2 and 3 encode the same protein.", "evidence": [ { "database": "RefSeq", "id": "NP_001127834", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001127834" } ] }, { "annotation": "In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5SNQ9-1", "uniprot_ac": "Q5SNQ9", "uniprot_id": "MYCT1_DANRE", "mass": { "chemical_mass": 23235.0, "monoisotopic_mass": 23235.0 }, "refseq": { "ac": "NP_001076386", "name": "myc target protein 1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076386" }, "gene_names": [ { "name": "myct1", "type": "recommended", "evidence": [ { "id": "Q5SNQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ9" } ] }, { "name": "myct1a", "type": "synonym", "evidence": [ { "id": "NP_001076386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076386" } ] }, { "name": "myct1", "type": "synonym", "evidence": [ { "id": "NP_001076386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076386" } ] }, { "name": "si:dkey-12h9.2", "type": "synonym", "evidence": [ { "id": "NP_001076386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076386" }, { "id": "Q5SNQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ9" } ] } ], "protein_names": [ { "name": "Myc target protein 1 homolog", "type": "recommended", "evidence": [ { "id": "Q5SNQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ9/entry#names_and_taxonomy" } ] }, { "name": "myc target 1", "type": "synonym", "evidence": [ { "id": "NP_001076386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076386" } ] }, { "name": "myc target protein 1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001076386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076386" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CA470630.1, GFIL01027369.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476794 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. On Mar 15, 2007 this sequence version replaced XP_001336908.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001076386", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076386" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5SNQ9", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "myct1", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041001-143", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-143", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5SNQ9", "url": "https://alphafold.ebi.ac.uk/entry/Q5SNQ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000056125", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000056125", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "796556", "url": "https://www.ncbi.nlm.nih.gov/gene/796556", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:796556", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796556", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SFWGNNG", "url": "https://omabrowser.org/oma/group/SFWGNNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5SNQ9", "url": "https://www.orthodb.org/?gene=Q5SNQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14869", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14869", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14869:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14869:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5SNQ9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5SNQ9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001076386", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076386", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5SNQ9", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5SNQ9-1", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041001-143", "url": "https://zfin.org/ZDB-GENE-041001-143", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MADNSTHPIMKILESFGLTDVILAFFLSMVVGLLLGALVYMILTWMSRRRASATITRIPVHQSRSTTRSSSPRSRLGYSRHSSGYDRRSNNSLASAAFSFHRQTSSSPIDYGDSTGRKSSFRASTFHPLLQCSQIAREAEEGAQGSLPRTPTLTTSPGAAGSTSTVSSMITPPRARNRPDSFWGNSNLRGFHAGQTPPPAYDSIIRAYQETTT", "length": 213, "header": "sp|Q5SNQ9-1|MYCT1_DANRE Isoform 1 of Myc target protein 1 homolog OS=Danio rerio OX=7955 GN=myct1 PE=3 SV=1 CANONICAL=Q5SNQ9-1" }, "isoforms": [ { "isoform_ac": "Q5SNQ9-1", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ9/entry#Q5SNQ9-1", "sequence": { "sequence": "MADNSTHPIMKILESFGLTDVILAFFLSMVVGLLLGALVYMILTWMSRRRASATITRIPVHQSRSTTRSSSPRSRLGYSRHSSGYDRRSNNSLASAAFSFHRQTSSSPIDYGDSTGRKSSFRASTFHPLLQCSQIAREAEEGAQGSLPRTPTLTTSPGAAGSTSTVSSMITPPRARNRPDSFWGNSNLRGFHAGQTPPPAYDSIIRAYQETTT", "length": 213, "header": "sp|Q5SNQ9-1|MYCT1_DANRE Isoform 1 of Myc target protein 1 homolog OS=Danio rerio OX=7955 GN=myct1 PE=3 SV=1 CANONICAL=Q5SNQ9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 171, "start_aa": "Thr", "end_pos": 171, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr171", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "Q5SNQ9", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ9" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:796556", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796556", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUL5-1", "protein_name": "Myc target 1", "gene_name": "Myct1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANNTTSLGSPWPENFWEDLIMSFTVSVAIGLAIGGFLWALFVFLSRRRRASAPISQWSPTRRPRSSYNHGLSRTGFYRHSGCERRSNLSLASLTFQRQASLELANSFPRKSSFRASTFHPFLQCPPLPVETESQLMTLPASTTPSTISTVHSPSRPDFRWSSNSLRMGLSTPPPPAYESIIKAFPDS", "length": 188 }, "evidence": [ { "id": "RGD:1311467", "url": "https://alliancegenome.org/gene/RGD:1311467#orthology", "database": "AGR" }, { "id": "MGI:1915882", "url": "https://alliancegenome.org/gene/MGI:1915882#orthology", "database": "AGR" }, { "id": "HGNC:23172", "url": "https://alliancegenome.org/gene/HGNC:23172#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-143", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-143#orthology", "database": "AGR" }, { "id": "Q5SNQ9", "url": "https://omabrowser.org/oma/group/Q5SNQ9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FG94-1", "protein_name": "Myc target protein 1 homolog", "gene_name": "myct1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASNETNALQEMLKNIDFEELILAFCLSMLIGLLIGILIFLLLTWMSRTRASVRMIRHQTQSSESKGCHLKHYKSHGFDKNSEYAGRAALNLHRQTSVDPNELLGRSPSFQNSTFRPPVKKTKKSSDEMEDDNQAALLPNITDPFSMEPAESFWLGKGSLRGFLPRQTPPPAYDSVIHIFQETCT", "length": 185 }, "evidence": [ { "id": "MGI:1915882", "url": "https://alliancegenome.org/gene/MGI:1915882#orthology", "database": "AGR" }, { "id": "HGNC:23172", "url": "https://alliancegenome.org/gene/HGNC:23172#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MGM5-1", "protein_name": "MYC target 1", "gene_name": "MYCT1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGCVKIIFLLPNYKDTDSKFFWTHWLFFSLLFFVDIMANNTTSLGSPWPENFWEDVIMSFTVSVATVLVIGGFIWALSVCLSRRRASAPISQWSSSRRSRSSYTHGLNRNGFYRHSGCERRSNLSLASLTFQRQASLEQANSFPRKSSFRGSTFHPFLQCPPLPVETESQLVTFPSSTTSSSINTSHSLGRPDFHWSSNSLRLGVSTPPPPAYESIIKAFSDS", "length": 224 }, "evidence": [ { "id": "Q5SNQ9", "url": "https://omabrowser.org/oma/group/Q5SNQ9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1NWT7-1", "protein_name": "MYC target 1", "gene_name": "MYCT1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDRNSTYSPVSWPPKFWEQVTIAFTVSMLIGLVIGGIIWALFTCLSRRRASAHISQGNSSPFTRRSRPTSHSASRTGFYRNSSCERRSNLSLASLTFQRQASLEQANSFPRKLSFRASTFHPFLQSPPLPVETNSQLITLTPTNTTTTLVGSTTNGLSRPEFHWSNNSLRICHSTQTPPPAYETIIKAFPDS", "length": 192 }, "evidence": [ { "id": "Q5SNQ9", "url": "https://omabrowser.org/oma/group/Q5SNQ9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8N699-1", "protein_name": "Myc target protein 1", "gene_name": "MYCT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTQVYEGLCKNYFSLAVLQRDRIKLLFFDILVFLSVFLLFLLFLVDIMANNTTSLGSPWPENFWEDLIMSFTVSMAIGLVLGGFIWAVFICLSRRRRASAPISQWSSSRRSRSSYTHGLNRTGFYRHSGCERRSNLSLASLTFQRQASLEQANSFPRKSSFRASTFHPFLQCPPLPVETESQLVTLPSSNISPTISTSHSLSRPDYWSSNSLRVGLSTPPPPAYESIIKAFPDS", "length": 235 }, "evidence": [ { "id": "RGD:1311467", "url": "https://alliancegenome.org/gene/RGD:1311467#orthology", "database": "AGR" }, { "id": "MGI:1915882", "url": "https://alliancegenome.org/gene/MGI:1915882#orthology", "database": "AGR" }, { "id": "HGNC:23172", "url": "https://alliancegenome.org/gene/HGNC:23172#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-143", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-143#orthology", "database": "AGR" }, { "id": "Q5SNQ9", "url": "https://omabrowser.org/oma/group/Q5SNQ9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R411-1", "protein_name": "Myc target protein 1", "gene_name": "Myct1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANNTTSLGSPWPENFWEDLIMSFTVSVAIGLAIGGFLWALFVFLSRRRRASAPISQWSPTRRPRSSYNHGLNRTGFYRHSGYERRSNLSLASLTFQRQASMELVNSFPRKSSFRASTFHPFLQCPPLPVETESQLMTLSASTTPSTLSTAHSPSRPDFRWSSNSLRMGLSTPPPPAYESIIKAFPDS", "length": 188 }, "evidence": [ { "id": "RGD:1311467", "url": "https://alliancegenome.org/gene/RGD:1311467#orthology", "database": "AGR" }, { "id": "MGI:1915882", "url": "https://alliancegenome.org/gene/MGI:1915882#orthology", "database": "AGR" }, { "id": "HGNC:23172", "url": "https://alliancegenome.org/gene/HGNC:23172#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-143", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-143#orthology", "database": "AGR" }, { "id": "Q5SNQ9", "url": "https://omabrowser.org/oma/group/Q5SNQ9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "embryonic hemopoiesis", "id": "GO:0035162", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035162", "evidence": [ { "database": "UniProtKB", "id": "Q5SNQ9", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "Q5SNQ9", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5SNQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNQ9" } ], "ann_type": "Motif_Annotation", "uniprotkb_annotation": "Bipartite nuclear localization signal", "eco_id": "ECO_0000255", "start_pos": 48, "end_pos": 68, "start_aa": "Arg", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 171 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 4, "end_pos": 6 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5SNV1-1", "uniprot_ac": "Q5SNV1", "uniprot_id": "Q5SNV1_DANRE", "mass": { "chemical_mass": 292418.0, "monoisotopic_mass": 292418.0 }, "refseq": { "ac": "NP_001025383", "name": "zinc finger protein 292b", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025383" }, "gene_names": [ { "name": "znf292b", "type": "recommended", "evidence": [ { "id": "Q5SNV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ] }, { "name": "fj87a04", "type": "synonym", "evidence": [ { "id": "NP_001025383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025383" }, { "id": "Q5SNV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ] }, { "name": "si:busm1-189a20.4", "type": "synonym", "evidence": [ { "id": "NP_001025383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025383" }, { "id": "Q5SNV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ] }, { "name": "wu:fj87a04", "type": "synonym", "evidence": [ { "id": "NP_001025383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025383" }, { "id": "Q5SNV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ] }, { "name": "znf292b", "type": "synonym", "evidence": [ { "id": "NP_001025383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025383" } ] } ], "protein_names": [ { "name": "Zinc finger protein 292b", "type": "synonym", "evidence": [ { "id": "Q5SNV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 292b", "type": "synonym", "evidence": [ { "id": "NP_001025383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025383" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC118675.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AL954305.14. On Aug 6, 2005 this sequence version replaced XP_695110.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025383", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025383" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0AC58I455", "url": "https://www.uniprot.org/uniprotkb/A0AC58I455#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "Q5SNV1", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1#function" } ] } ], "disease": [ { "disease_id": "DOID:0061037", "recommended_name": { "id": "DOID:0061037", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0061037", "name": "autosomal dominant intellectual developmental disorder 64", "description": "An autosomal dominant intellectual developmental disorder characterized by mildly to severely impaired intellectual development (ID) with speech delays that has_material_basis_in heterozygous mutation in the ZNF292 gene on chromosome 6q14." }, "synonyms": [ { "id": "MONDO:0030934", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030934", "name": "intellectual developmental disorder, autosomal dominant 64", "description": "" }, { "id": "MONDO:0030934", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030934", "name": "ZNF292-related syndrome", "description": "" }, { "id": "MONDO:0030934", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030934", "name": "MRD64", "description": "" }, { "id": "MONDO:0030934", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030934", "name": "ZNF292-related neurodevelopmental disorder", "description": "" }, { "id": "MONDO:0030934", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030934", "name": "intellectual developmental disorder, autosomal dominant 64", "description": "" }, { "id": "MONDO:0030934", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030934", "name": "mental retardation, autosomal dominant 64", "description": "" }, { "id": "MIM:619188", "resource": "MIM", "url": "https://www.omim.org/entry/619188", "name": "Intellectual developmental disorder, autosomal dominant 64", "description": "Intellectual developmental disorder, autosomal dominant 64" } ], "unlinked_id_list": [], "evidence": [ { "id": "0061037", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061037" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5SNV1", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "znf292b", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-9559", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-9559", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "566732", "url": "https://www.ncbi.nlm.nih.gov/gene/566732", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058902", "url": 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"categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-9559", "url": "https://zfin.org/ZDB-GENE-030131-9559", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MADEEAEQERSARSDTSSALQALATRLQEIRGALEDRAEPAEESASQYCYQFCQTLLEYASLWRIEDEPLPVLEVYITALLSFAQACPLLSAQCEEVPLLLERLSLSCAELLLSLPWNIPDALWDRFRTSVQIAHPLVQEKGISHLTILSTIAREQGVWSNPTLQAILSSETPAGEEVHEFLTAEGPTLLRMRLKQLMKEGRADQAAALAKACADLSEFEEKGHFKQMHLVCLCTVAPQDVVMEELSKVDCRDALEMICNLEADGEEKAAFTLCSAFLTRQILQEDSYCAWELTLFWGNLLKRLEPSEQGFLDRCRQMSFLSKTVFHLLFFIKFIQTEMGKVGLPTCVEICIRALRLDSCEGSTKATVCKTISCLLPSDLEVKRACQLTEFLLEPTVDSYYAVETLYNEPDQKLDVEDLLVSNSLRCELLLVLKTQWPFDPEYWNWKALKRHCLGLMGEEASIVSSIDELNDGDLEGLGEFNEDFKDMSQCFLDTTNELNDMADQKQKNREMKKLREKGFVSARFRNWQAYMQYCVLCDKEFLGHRIVRHAVTHFKDGSYFCPICLETFETKETLEPHVASHVKLSCKERLAAMKTSKQLASPKTATPDIPSLKAKSSENQVRKPKTKSSSGGQANKLSSKGSNDSEGFGGEGNTCPVQYCRKGFKYFRNLIAHVKDHGDNEEAKRFLEMQSTKIVCQYCRRQFVSVDHLNDHLQMHCGIKPYICIQLNCKASFNSNTELIVHKKEHTVFKARCMFPGCGKIFHEAYKLYDHEAQHYKTFTCKAPDCGKVFHSQSELDLHAESHITKVESKNTESQSIEPAEPHPEQCNQTEQDSAQPDPLSVMDLNDRGAESEEDRQSGMVIVKHSVENMLNSEFAVSADCVQPGTSKPDQLPTHQHIPQINDHPGKSTEGTRASRLKPHRPEESLLEALMSNSDPMPSTSSYQSVLEDLLPAPATNGQLQSADSASTTPLYNNGVFRQYNPNPLTPSQASYQSLHSSRRTPPPQAAHNATPLVSLGQMLPPVSQTLPLQMASVPNDGQVLENKCVKPIDTTIVQVKERHKCPHETCTRDYSSYRSVTKHMKAVHPDFYTQWKLAKKNNVAGRSKHRSVNGGHSSVVTPRDQPAQRRPGVQTQKSLSQPTCYPSNCANPKYPSVSSHIAASPGHIRSNEMDNILDPIVLSQLGNGNNQPQMATDHLWDPRNNSVLQQQRCHSMTQSMNTLSSSHFTHMNPASNDDAQQRGTSYTTLQSKRNGYPVPARADINQKLSNTSNDDLHAVGELNPTQVMGPNAVVTAQSSAETNLGSAPMSVLSSYTDTMNSSVPKESSAAYLPQAEDSFPPVPSAQCLVKLERETTVGFPLSNNAPPSNGSSPSSQDNTGNASSDGEHKKVKRNRRTKWPAIVKDGKFICCRCYREFNSPKSLGGHLSKRAYCKPFEEADLTADLPSSFLDLLNSPHPTPSSHVTLPQIKGPLDPKLYPNVTFPQANGTYTSIDKQMGGTLQSQSSPCVGSAQEQQMVPNPCGSYAQSSRLSETSVIQHTGSVKHQLQPSYSEMSSTLFNDSVSDPLLTQLLADDRSTSSLNSSSSDQVFQNETLNRMKDNKEKTPNINVSDLSNDGLLAAMANFTQNMVSEKSVKERLREQILAGEFHKKGSLPRGSSVDSSSSQMSVSSPVSGDLQRTSNLVTNTPQSEQQPNVNASDVLVETVSQMSPNDGLNHTMSSVLPEGAVNDQPSNMPITSVDEVLEIQKALEKLDLDREISEVIRTVDVPAVIPVQPTKPELKPTKPKVLPTVKPSYVKPFVCDVKGCTYSAMTKDALMKHLVKTHNYTEDMLAQMKDQFNVAPFRCQKCSKAFTRNSNLKAHYISIHNYSQEEVKKMKIRPQSSQRLLESDKGSPCSVPEVPRTVKNTPVVDARQPPKDVTCPSGSMRHDTVKTPHCIPPPFVPQSAFVPQSRSLAAGTPTVNQMAVQPSVIMSSHSSVTQRIDQNANGWFPTPTPVPAQAQLSPLKEILPIAPFTQNPSALLHKVNLPLDKKPKPSKPKVAKPKESPKKIKEKKPEADDAFSPYRPYRCVHQGCVAAFTIQHNLILHYKAVHQSALPKFEINSHDEQNDEEAEDMDRVEEREDKLDVDVKEVDEFRCQVKDCSSIFQTVPDMLQHYLQLHKLPLEKAGAMMCSINLGRFQCDQSECSETFTGFWKYIRHVDKKHKETQLSKVNAVAGVFRCPMEGCEGAYSTRSNLLRHTMKKHQEVYKRLLMSPRGTKTGVKLGRPRKFQSHVVEKENRAMNKKSIKKPILKKKKPNTNNWTKYGKPILKTQEEASAMCTKRLQLQYACMIKGCETVTSSERNIMKHYLQHGLPKQYLEEQRSNFIYCKKIPRSKYKRIASRSDDTDKSEESSIETTENEEVAEPGQSESEFSKPTSGKESTEDPDLSDGKPSTDTCSEISVVVKRRRGRPRKGNVKERKPTGPKRMTRQGIAGSSSVSYADLNSDSTSSSTTLIQEEASSKNTPLSSFKPMGFEVSFLQFLQESKTSQKRKATVPLNGNAHKRMTTFQLKTATVVCKRADAELRPREALKLVEFKNPQKLTSLSNVKFEVQKVFTNVLEILLKQLQEMRPTVILQKEK", "length": 2619, "header": "tr|Q5SNV1-1|Q5SNV1_DANRE Isoform 1 of Zinc finger protein 292b OS=Danio rerio OX=7955 GN=znf292b PE=3 SV=1 CANONICAL=Q5SNV1-1" }, "isoforms": [ { "isoform_ac": "A0AC58I455-1", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1/entry#A0AC58I455-1", "sequence": { "sequence": "MADEEAELERSARSDTSSALQALATRLQEIRGALEDRAEPAEESASQYCYQFCQTLLEYASLWRIEDEPLPVLEVYITALLSFAQACPLLSAQCEEVPLLLERLSLSCAELLLSLPWNIPDALWDRFRTSVQEKGISHLTILSTIAREQGVWSNPTLQAILSSETPAGEEVHEFLTAEGPTLLRMRLKQLMKEGRADQAAALAKACADLSEFEEKGHFKQMHLVCLCTVAPQDVIMEELSKVDCRDALEMICNLEADGEEKAAFTLCSAFLTRQILQEDSYCAWELTLFWGNLLKRLEPSEQGFLDRCRQMSFLSKTVFHLLFFIKFIQTEMGKVGLPTCVEICIRALRLDSCEGSTKATVCKTISCLLPSDLEVKRACQLTEFLLEPTVDSYYAVETLYNEPDQKLDVEDLLVSNSLRCELLLVLKTQWPFDPEYWNWKALKRHCLGLMGEEASIVSSIDELNDGDLEGLGEFNEDFKDMSQCFLDTTNELNDMADQKQKNREMKKLREKGFVSARFRNWQAYMQYCVLCDKEFLGHRIVRHAVTHFKDGSYFCPICLETFETKETLEPHVASHVKLSCKERLAAMKTSKQLASPKTATPDIPSLKAKSSENQVRKPKTKSSSGGQANKLSSKGSNDSEGFGGEGNTCPVQYCRKGFKYFRNLIAHVKDHGDNEEAKRFLEMQSTKIVCQYCRRQFVSVDHLNDHLQMHCGIKPYICIQLNCKASFNSNTELIVHKKEHTVFKARCMFPGCGKIFHEAYKLYDHEAQHYKTFTCKAPDCGKVFHSQSELDLHAESHITKVESKNTESQSIEPAEPHPEQCNQTEQDSAQPDPLSVMDLNDRGAESEEDRQSGMVIVKHSVENMLNSEFAVSADCVQPGTSKPDQLPTHQHIPQINDHPGKSTEGTRASRLKPHRPEESLLEALMSNSDPMPSTSSYQSVLEDLLPAPATNGQLQSADSASTTPLYNNGVFRQYNPNPVTPSQASYQSLHSSRRTPPPQAAHNATPLVSLGQMLPPVSQTLPLQMASVPNDGQVLENKCVKPIDTTIVQVKERHKCPHETCTRDYSSYRSVTKHMKAVHPDFYTQWKLAKKNNVAGRSKHRSVNGGHSSVVTPRDQPAQRRPAVQTQKSLSQPTCYPSNCANPKYPSVSSHIAASPGHIRSNEMDNILDPIVLSQLGNGNNQPQMATDHLWDPRNNSVLQQQRCHSMTQSMNTLSSSHFTHMNPASNDDAQQRGTSYTTLQSKRNGYPVPARADINQKLSNTSNDDLHAVGELNPTQVMGPNAVVTAQSSAETNLGSAQMSVLSSYADTMNSSVPKESSAAYLPQAEDSFPPVPSAQCLVKLERETTVGFPLSNNAPPSNGSSPSSQDNTGNASSDGEHKKVKRNRRTKWPAIVKDGKFICCRCYREFNSPKSLGGHLSKRAYCKPFEEADLTADLPSSFLDLLNSPHPAPSSHVTLPQIKGPLDPKLYPNVTFPQANGTYTSIDKQMGGTLQSQSSPCVGSAQEQQMVPNPCGSYAQSSRLSETSVIQHTGSVKHQLQPSYSEMSSTLFNDSVSDPLLTQLLADDRSTSSLNSSSSDQVFQNETLNRMKDNKEKTPNINVSDLSNDGLLAAMANFTQNMVSEKSVKERLREQILAGEFHKKGSLPRGSSVDSSSSQMSVSSPVSGDLQRTSNLVTNTPQSEQQPNVNASDVLVETVSQMSPNDGLNHTMSSVLPEGAVNDQPSNMPITSVDEVLEIQKALEKLDLDREISEVIRTVDVPAVIPVQPTKPELKPTKPKVLPTVKASYVKPFVCDVKGCTYSAMTKDALMKHLVKTHNYTEDMLAQMKDQFNVAPFRCQKCSKAFTRNSNLKAHYISIHNYSQEEVKKMKIRPQSSQRLLESDKGSPCSVPEVPRTVKNTPVVDARQPPKDVTCPSGSMRHDTVKTPHCIPPPFVPQSAFVPQSRSLAAGTPTVNQMAVQPSVIMSSHSSVTQRIDQNANGWFPTPTPVPAQAQLSPLKEILPIAPFTQNPSALLHKVNLPLDKKPKPSKPKVAKPKESPKKIKEKKPEADDAFSPYRPYRCVHQGCVAAFTIQHNLILHYKAVHQSALPKFEINSHDEQNDEEAEDMDQVEEREDKLDVDVKEVDEFRCQVKDCSSIFQTVPDMLQHYLQLHKLPLEKAGAMMCSINLGRFQCDQSECSETFTGFWKYIRHVDKKHKETQLSKVNAVAGVFRCPMEGCEGAYSTRSNLLRHTMKKHQEVYKRLLMSPRGTKTGVKLGRPRKFQSHVVEKENRAMNKKSIKKPILKKKKPNTNNWTKYGKPILKTQEEASAMCTKRLQLQYACMIKGCETVTSSERNIMKHYLQHGLPKQYLEEQRSNFIYCKKIPRSKYKRIASRSDDTDKSEESSIETTENEEVAEPGQSESEFSKPTSGKESTEDPDLSDGKPSTDTCSEISVVVKRRRGRPRKGNVKERKPTGPKRMTRQGIAGSSSVSYADLNSDSTSSSTTLIQEEASSKNTPLSSFKPMGFEVSFLQFLQESKTSQKRKATVPLNGNAHKRMTTFQLKTATVVCKRADAELRPREALKLVEFKNPQKLTSLSNVKFEVQKVFTNVLEILLKQLQEMRPTVILQKEK", "length": 2612, "header": "tr|A0AC58I455-1|A0AC58I455_DANRE Computationally mapped isoform of Zinc finger protein 292b isoform X1 OS=Danio rerio OX=7955 GN=znf292b PE=3 SV=1 CANONICAL=Q5SNV1-1" }, "locus": {} }, { "isoform_ac": "Q5SNV1-1", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1/entry#Q5SNV1-1", "sequence": { "sequence": "MADEEAEQERSARSDTSSALQALATRLQEIRGALEDRAEPAEESASQYCYQFCQTLLEYASLWRIEDEPLPVLEVYITALLSFAQACPLLSAQCEEVPLLLERLSLSCAELLLSLPWNIPDALWDRFRTSVQIAHPLVQEKGISHLTILSTIAREQGVWSNPTLQAILSSETPAGEEVHEFLTAEGPTLLRMRLKQLMKEGRADQAAALAKACADLSEFEEKGHFKQMHLVCLCTVAPQDVVMEELSKVDCRDALEMICNLEADGEEKAAFTLCSAFLTRQILQEDSYCAWELTLFWGNLLKRLEPSEQGFLDRCRQMSFLSKTVFHLLFFIKFIQTEMGKVGLPTCVEICIRALRLDSCEGSTKATVCKTISCLLPSDLEVKRACQLTEFLLEPTVDSYYAVETLYNEPDQKLDVEDLLVSNSLRCELLLVLKTQWPFDPEYWNWKALKRHCLGLMGEEASIVSSIDELNDGDLEGLGEFNEDFKDMSQCFLDTTNELNDMADQKQKNREMKKLREKGFVSARFRNWQAYMQYCVLCDKEFLGHRIVRHAVTHFKDGSYFCPICLETFETKETLEPHVASHVKLSCKERLAAMKTSKQLASPKTATPDIPSLKAKSSENQVRKPKTKSSSGGQANKLSSKGSNDSEGFGGEGNTCPVQYCRKGFKYFRNLIAHVKDHGDNEEAKRFLEMQSTKIVCQYCRRQFVSVDHLNDHLQMHCGIKPYICIQLNCKASFNSNTELIVHKKEHTVFKARCMFPGCGKIFHEAYKLYDHEAQHYKTFTCKAPDCGKVFHSQSELDLHAESHITKVESKNTESQSIEPAEPHPEQCNQTEQDSAQPDPLSVMDLNDRGAESEEDRQSGMVIVKHSVENMLNSEFAVSADCVQPGTSKPDQLPTHQHIPQINDHPGKSTEGTRASRLKPHRPEESLLEALMSNSDPMPSTSSYQSVLEDLLPAPATNGQLQSADSASTTPLYNNGVFRQYNPNPLTPSQASYQSLHSSRRTPPPQAAHNATPLVSLGQMLPPVSQTLPLQMASVPNDGQVLENKCVKPIDTTIVQVKERHKCPHETCTRDYSSYRSVTKHMKAVHPDFYTQWKLAKKNNVAGRSKHRSVNGGHSSVVTPRDQPAQRRPGVQTQKSLSQPTCYPSNCANPKYPSVSSHIAASPGHIRSNEMDNILDPIVLSQLGNGNNQPQMATDHLWDPRNNSVLQQQRCHSMTQSMNTLSSSHFTHMNPASNDDAQQRGTSYTTLQSKRNGYPVPARADINQKLSNTSNDDLHAVGELNPTQVMGPNAVVTAQSSAETNLGSAPMSVLSSYTDTMNSSVPKESSAAYLPQAEDSFPPVPSAQCLVKLERETTVGFPLSNNAPPSNGSSPSSQDNTGNASSDGEHKKVKRNRRTKWPAIVKDGKFICCRCYREFNSPKSLGGHLSKRAYCKPFEEADLTADLPSSFLDLLNSPHPTPSSHVTLPQIKGPLDPKLYPNVTFPQANGTYTSIDKQMGGTLQSQSSPCVGSAQEQQMVPNPCGSYAQSSRLSETSVIQHTGSVKHQLQPSYSEMSSTLFNDSVSDPLLTQLLADDRSTSSLNSSSSDQVFQNETLNRMKDNKEKTPNINVSDLSNDGLLAAMANFTQNMVSEKSVKERLREQILAGEFHKKGSLPRGSSVDSSSSQMSVSSPVSGDLQRTSNLVTNTPQSEQQPNVNASDVLVETVSQMSPNDGLNHTMSSVLPEGAVNDQPSNMPITSVDEVLEIQKALEKLDLDREISEVIRTVDVPAVIPVQPTKPELKPTKPKVLPTVKPSYVKPFVCDVKGCTYSAMTKDALMKHLVKTHNYTEDMLAQMKDQFNVAPFRCQKCSKAFTRNSNLKAHYISIHNYSQEEVKKMKIRPQSSQRLLESDKGSPCSVPEVPRTVKNTPVVDARQPPKDVTCPSGSMRHDTVKTPHCIPPPFVPQSAFVPQSRSLAAGTPTVNQMAVQPSVIMSSHSSVTQRIDQNANGWFPTPTPVPAQAQLSPLKEILPIAPFTQNPSALLHKVNLPLDKKPKPSKPKVAKPKESPKKIKEKKPEADDAFSPYRPYRCVHQGCVAAFTIQHNLILHYKAVHQSALPKFEINSHDEQNDEEAEDMDRVEEREDKLDVDVKEVDEFRCQVKDCSSIFQTVPDMLQHYLQLHKLPLEKAGAMMCSINLGRFQCDQSECSETFTGFWKYIRHVDKKHKETQLSKVNAVAGVFRCPMEGCEGAYSTRSNLLRHTMKKHQEVYKRLLMSPRGTKTGVKLGRPRKFQSHVVEKENRAMNKKSIKKPILKKKKPNTNNWTKYGKPILKTQEEASAMCTKRLQLQYACMIKGCETVTSSERNIMKHYLQHGLPKQYLEEQRSNFIYCKKIPRSKYKRIASRSDDTDKSEESSIETTENEEVAEPGQSESEFSKPTSGKESTEDPDLSDGKPSTDTCSEISVVVKRRRGRPRKGNVKERKPTGPKRMTRQGIAGSSSVSYADLNSDSTSSSTTLIQEEASSKNTPLSSFKPMGFEVSFLQFLQESKTSQKRKATVPLNGNAHKRMTTFQLKTATVVCKRADAELRPREALKLVEFKNPQKLTSLSNVKFEVQKVFTNVLEILLKQLQEMRPTVILQKEK", "length": 2619, "header": "tr|Q5SNV1-1|Q5SNV1_DANRE Isoform 1 of Zinc finger protein 292b OS=Danio rerio OX=7955 GN=znf292b PE=3 SV=1 CANONICAL=Q5SNV1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1457, "start_aa": "Thr", "end_pos": 1457, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1457", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1991, "start_aa": "Thr", "end_pos": 1991, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1991", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1993, "start_aa": "Thr", "end_pos": 1993, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1993", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Hematopoietic gene expression profile in zebrafish kidney marrow.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2004", "authors": "Song Huai-Dong, Sun Xiao-Jian, Deng Min, Zhang Guo-Wei, Zhou Yi, Wu Xin-Yan, Sheng Yan, Chen Yi, Ruan Zheng, Jiang Chun-Lei, Fan Hui-Yong, Zon Leonard I, Kanki John P, Liu Ting Xi, Look A Thomas, Chen Zhu", "evidence": [ { "database": "UniProtKB", "id": "Q5SNV1", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ], "reference": [ { "type": "PubMed", "id": "15520368", "url": "https://glygen.org/publication/PubMed/15520368" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "Q5SNV1", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "Q5SNV1", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:566732", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566732", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZXZ1-1", "protein_name": "Zinc finger protein 292", "gene_name": "Zfp292", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADDEAEQERLSGGSCAAELRRLGERLQELERRLCESREPAVEAAAAYCRQLCQTLLEYAEKWKTSEDPLPLLEVYTVAIQSYVKARPYLTSECESVALVLERLALSCVELLLCLPVELSDKQWEQFQTLVQVAHETLMESGSCELHFLATLAQETGVWKNAVLSTILSQEPLDKEKVNEFLAFEGPILLDMRIKHLIKTNQLSQATALAKLCSDHPEIGTKGSFKQTYLVCLCTSSPSEKLIEEISEVDCKDALEMICNLESEGDEKSALVLCTAFLSRQLQQGDMYCAWELTLFWSKLQQRVEPSVQVYLERCRQLSLLTKTVYHIFFLIKVINSETEGAGLATCIELCVKALRLESTENTEVKISICKTISCLLPEDLEVKRACQLSEFLIEPTVDAYYAVEMLYNQPDQKYDEENLPIPNSLRCELLLVLKTQWPFDPEFWDWKTLKRQCLALMGEEASIVSSIDELNDSEVYEKVDYQGERGDTSVNGLSAGLGTDSSLLIDTGDEKQKKKEIKELKDRGFISARFRNWQAYMQYCLLCDKEFLGHRIVRHAQKHYKDGVYSCPICAKNFNSKESFVPHVTLHVKQSSKERLAAMKPLRRLGRPPKITATHENQKTNTNTVAKQEQRPIKKNSLYSTDFIVFNDNDGSDDENDDKDKSYEPEVIPVQKPVPVNEFNCPVTFCKKGFKYFKNLIAHVKGHKDSEDAKRFLEMQSKKVICQYCRRHFVSVTHLNDHLQMHCGSKPYICIQMKCKAGFNSYAELLAHRKEHQVFRAKCLFPKCGRIFSQAYLLYDHEAQHYNTYTCKFTGCGKVYRSQSEMEKHLDDHSAPEKVLPPEDQLTPSGNEVTQNSEGTTGEGRSEHSIEKSEGPDRSGDWEKNKAESAVTTHSQISASELRQADIPLSDGLGNPGDTTVLQTNEVAVSIKVSVNHGIEDDFGKQENLTMEGTGEPLITDVHKPGEGAGVHFRHPGFQEKKDHECLNKAQTAQNSLANSESLKMGDLNPQSLERQVNTLTTFSVQNEGGLEDSSQICKFECGGDVKTSSSLYDLPLKTLESVAFVPSQPDLSSPLGAPSVPPKAPGQKFSCQVEGCTRTYNSSQSIGKHMKTAHPDQYAAFKLQRKTKKGQKSNNLSTPDHGKCVYFLPSQVSSSNHAFFTPQTKASGNPACSAQLQHVSPSIFPAHLASVSTSLLPSVESVLSPNMPSQDKHVQDGMLCSQMENLSNAALPAQMEDLTKTVLPLNIDSGSDPFLPLPTENSSLFSSPAHSENNSVFSQLESSTNHYPSPTEGNLNSSFLKGGSSENGAFPSHVSTADDLSSTSAQQSAPKKVKKDRGRGPNGKERKPKHNKRAKWPAIIRDGKFICSRCYRAFTNPRSLGGHLSKRSYCKPLDGAEIAQELLQTNRQPSLLASMILSTSTVNMQQPQQSNCNPETCFKDPSFLQLLSVENRPNFLPSTFPRCDVSNFNAGVSQEGSEIIKQALETAGIPSTFESAEMLSQVVPIGSVSDAAQVNAEGMPGPTVTPLLQTVCHTNTSPSSQNQTPNSKTSNLKECNSLPIFTTNDLLLKTIENGLCSNSFSSSTEPPQNFTNNSTHVSVISGPQNTRSNHLNKKGNSASKKRKKVTPAVIVSNTSQNVVPTDLTMGLASKNLTVPDTNTRDMIPDCEPQALVENLTQKLNNIDNHLFLTDVKESCKASLEPHTMLTPLTLKTENGDSRMMPLNSCTPVSSDLQISEDNVIQNFEKTLEIIKTAMNSQILEVKSGSQGTGETTQNAQINYSMQLPSVNSIPDNKLPDSSQCSSFLTVMPTKHNIPQSEALHKEDQIQDILEGLQNLKLETDISAPPSQATLINKSVALSPTPTKSTPNIIVQPVSEVIHVQLNDRVNKPFVCQNQGCNYSAMTKDALFKHYGKIHQYTPEMILEIKKNQLKFAPFKCVVPTCTKTFTRNSNLRAHCQLVHHFTIEEMVKLKIKRPYGRKSQGENLSSPQINQVKKQLPMAEEAKTESQPAFEVPAVAGEDALDNVAVIPENQLAEKKSPEKPESSSQPVTASTEQYNANLGNLKTKGRKNKRHRKEKEEKREKNPVSQSFEFPTRYSSYRPYCCVHQGCFAAFTIQQNLILHYQAVHKSNLPTFSAEVEEESEAVKESEETEPKQSMKEFRCQVSDCSRIFQAITGLIQHYMKLHEMTPEEIESMTAAVDVGKFPCDQLECKSSFTTYLSYVVHLEVDHGIGTRTSKTEEDGIYKCDCEGCDRIYATRSNLLRHIFNKHNDKHKAHLIRPRKLTGQENISSKANQEKSKSKHRAIKHNRFGKDGMKGPKTKRKKKSNLESKSAKIVQIEEDKPYSLKRGKHVYSIKARNDALSECTSKFVTQYPCMIKGCTSVVTSESNIIRHYKCHKLSKAFTSQHRNILIVFKRYGNPQEKEVSEQEDEKNDKKDPDSSVLEKNDNSQPASIPQEEGMKGEKDEMDELTELFITKLINEDSTNTETQVSTTLKVNNDFQEHDSCISERQKTGNLKRVYKEKNITQNKKRKIDKTEPEVPLVVNKTHKEEETAVAVQTTEEHPASFDWSSFKPMGFEASFLKFLEESAVKQKKNTDRDHSHSGSKRGSHSNSRKNVDKTAVTGGNHVCSCKESEIFVQFANPSKLQCSENVKIVLDKTLKDCSELVLKQLQEMKPTVSLKKLEVLSNDPDRTVLKELSLGKATGRGQY", "length": 2706 }, "evidence": [ { "id": "HGNC:18410", "url": "https://alliancegenome.org/gene/HGNC:18410#orthology", "database": "AGR" }, { "id": "MGI:1353423", "url": "https://alliancegenome.org/gene/MGI:1353423#orthology", "database": "AGR" }, { "id": "RGD:61931", "url": "https://alliancegenome.org/gene/RGD:61931#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-9559", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-9559#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FBU0-1", "protein_name": "Zinc finger protein 292a", "gene_name": "znf292a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEEEGSANEAVALKHKFQDLISELKRSSESTLDASNSFCQDFCQILMHHGCQWRPDEDLLPLLELYTAAIMCCAEASPFLSPECEHVTDVLNKLSWSCLNLLLSFSEQIPGALWEKFQTSVKMAHGILQAHGNSQLQALLTLAEDNGIWSNATLCSILSNDLPNVERVHEFLSREGAELLHMRIKHLIKEKDMEKAARLAKTCAEFPEFGGKKNFRQIYLVCLCEITPQQELMHEIKEVDCKEALDMICNLESEEDEKGALSLCTAFFKRQLLSGDAYCAWELTLFWSKLLIRLESKQAFLEQCRLLARLSESVYHILLLIKVIQAEVDTDGLSVCIEMCIQALKMGVHDNEDCNITICKTISCLLPLDLEVKQACQLTEFLIKPSLESYYAVETLFNEPDQKLDQEDPPILNSLRCDLLLALKIKWPFDPEFWDWKTLKRQCLALMGQEATAILSSDKFTDSDDNEFHDLDEKYFQHFTDNPSYELFEVGTERKKKKNEFKKVKEKGFVSARFRNWQAYMQYCVLCDKEFLGHRIVKHALKHVQDGVFRCPICAKTFDSRTVLEPHVASHVKQSCSERLAAMGVSKKRTDPKLTPASSTLKKEEHYSDTAAKVSQENTCNNNLYTSIGSTSTDVKSKTKSSSSSTSSSSSPKQGNPIRDVNNTKDCCCPVTSCQKVFKYFRNLVAHVKAHKNEQEATDFLQLQSRKAMCQYCHRQFVNLTHLNDHVQMHSGDKPYFCVQLGCNCRFSSHAELLMHRKLHAEFQAQCAYPNCERIFNETYLLYDHEAQHYLTFPCKSHNCDKVFYTLAELDLHQRGHAKQVDHSAIDRRSHLHLEVAPQACPASELPQNQIKDFTPVEIKCSVQNIAGTTQDSTVQPEHLVLHTAQLKETENNSETSAVEPESTTSHCPQKSKRLESCYVKLKPIPIKFNDAVYLNTLKNADTETQALLKDKKLFSFIKIPLKPPTPKSSLAVTKENREEHLTHICPFETCTRKYSTSKSLSRHVKNVHAEAFEEWKLSKKYKRIAQVASKKSSSKHMTTNMPTPLLVKKWKGCSQKTERVNLQESAIQSPSSIFTNHVNMQSIGTKFCSQFENPPSAASTNQSGLMQLPDAQAWALPSMESLSSGFSEHGSYSSTILSENQHTNPSYHSDTILDYPSASSYDDIIPLPGNAHAPSGVMNEASKYVSSSLRVLHALNGDQTCDLSQVESSVNLEDISISNDLHAGALSGQNVSLYFPSEASSVSMQSMENSNKEMSSECTDAAFASEIKCMSDILNPNFKESSEDFFGATPVNDDKTPDDFCNHEMALEGPEGITSDDQTVLDSGENRKCKKIKSSKRTKWPAIIQDGKVICCRCYREFSSTKSLGGHLSKRSQCKPVDEIDLTADLPVSFLDFLNDPDISTVQMPLPANDILEDNHKSFIYAPSESSTFNDNTLTSVHGTESIPNINANEPSQDHSEIATNPNLFNSPVSNTATEMIADTEIIPENAGEDGIILEIERALQRLDLVDVLSDKSVPESTNLQELSSKSDTRNDQQNTIKDPVQTEQKSVLKPFKCKEDACTYGAMTKEALFKHFSRVHDYSDERINEIKKNPDRLAPYGCHLCSKTFTRTTGLKIHYKNVHHFSKDEISVLKIGLGFRKPKKPAPESETVHSALIDKQANKSEKIQHQVDPKLTVSTVKSNVDGKPKIVSKKKKQATKSSLTVGTTKSCKTTEETQKNVGNLDRLSTTCIKLEAPAQNAESHASDLNHPGIFGAQELSGLSSPHLFNKVNATNEEYATPQFFGQIGTKSSVTEDTQEKTMAVGNTDCGDSVDVYRPYRCIHEGCVAAFSIQQNLILHYRAMHQSECDEKNSAKATDGVFPVQEYRCQVKQCSKVVSKVTSLLKHYLLLHRCTLEKASALLSGVEVGTFQCDQSKCSAHFTCHLKYIDHIKNDHKAIKVSVDGDFESVNLTFGCQFKGCDRVYTTKSNLLRHLMKKHDATFETMKAKQEHVGDSVQTKKSSANPNSNNGKENIAKDKTKTKKKSSKKKEDKAQSQRVTLEKPALKSNEEASALCTQTFPLQYPCMIKNCDSVMNDERNILHHYTTHGLTEQYIEDQRSQFIFCIKSSEIPAADSTSQNVEVKEAQISEAQNPNSDVSSQDVGPEPAKEVEVNEAVTAVPPVVKRKRGRPRKSDCRNKVSVERKQSLRNCSDEHVKCMLKVSGSILRASNSQGNHRKNKVALKLYKSSKFQTTVLKFSQNPLSNPSKRLRKLKPIIRTKDQVKRVVNFRNPLKIERVNNVKIVMYKNQSPGSRLLLKQLQDMQPRVILEKRLHS", "length": 2313 }, "evidence": [ { "id": "HGNC:18410", "url": "https://alliancegenome.org/gene/HGNC:18410#orthology", "database": "AGR" }, { "id": "MGI:1353423", "url": "https://alliancegenome.org/gene/MGI:1353423#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O60281-1", "protein_name": "Zinc finger protein 292", "gene_name": "ZNF292", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADEEAEQERLSCGEGGCVAELQRLGERLQELELQLRESRVPAVEAATDYCQQLCQTLLEYAEKWKTSEDPLPLLEVYTVAIQSYVKARPYLTSECENVALVLERLALSCVELLLCLPVELSDKQWEQFQTLVQVAHEKLMENGSCELHFLATLAQETGVWKNPVLCTILSQEPLDKDKVNEFLAFEGPILLDMRIKHLIKTNQLSQATALAKLCSDHPEIGIKGSFKQTYLVCLCTSSPNGKLIEEISEVDCKDALEMICNLESEGDEKSALVLCTAFLSRQLQQGDMYCAWELTLFWSKLQQRVEPSIQVYLERCRQLSLLTKTVYHIFFLIKVINSETEGAGLATCIELCVKALRLESTENTEVKISICKTISCLLPDDLEVKRACQLSEFLIEPTVDAYYAVEMLYNQPDQKYDEENLPIPNSLRCELLLVLKTQWPFDPEFWDWKTLKRQCLALMGEEASIVSSIDELNDSEVYEKVVDYQEESKETSMNGLSGGVGANSGLLKDIGDEKQKKREIKQLRERGFISARFRNWQAYMQYCVLCDKEFLGHRIVRHAQKHYKDGIYSCPICAKNFNSKETFVPHVTLHVKQSSKERLAAMKPLRRLGRPPKITTTNENQKTNTVAKQEQRPIKKNSLYSTDFIVFNDNDGSDDENDDKDKSYEPEVIPVQKPVPVNEFNCPVTFCKKGFKYFKNLIAHVKGHKDNEDAKRFLEMQSKKVICQYCRRHFVSVTHLNDHLQMHCGSKPYICIQMKCKAGFNSYAELLTHRKEHQVFRAKCMFPKCGRIFSEAYLLYDHEAQHYNTYTCKFTGCGKVYRSQGELEKHLDDHSTPPEKVLPPEAQLNSSGDSIQPSEVNQNTAENIEKERSMLPSENNIENSLLADRSDAWDKSKAESAVTKQDQISASELRQANGPLSNGLENPATTPLLQSSEVAVSIKVSLNQGIEDNFGKQENSTVEGSGEALVTDLHTPVEDTCNDLCHPGFQERKEQDCFNDAHVTQNSLVNSETLKIGDLTPQNLERQVNNLMTFSVQNQAAFQNNLPTSKFECGDNVKTSSNLYNLPLKTLESIAFVPPQSDLSNSLGTPSVPPKAPVQKFSCQVEGCTRTYNSSQSIGKHMKTAHPDQYAAFKMQRKSKKGQKANNLNTPNNGKFVYFLPSPVNSSNPFFTSQTKANGNPACSAQLQHVSPPIFPAHLASVSTPLLSSMESVINPNITSQDKNEQGGMLCSQMENLPSTALPAQMEDLTKTVLPLNIDSGSDPFLPLPAESSSMSLFPSPADSGTNSVFSQLENNTNHYSSQIEGNTNSSFLKGGNGENAVFPSQVNVANNFSSTNAQQSAPEKVKKDRGRGPNGKERKPKHNKRAKWPAIIRDGKFICSRCYRAFTNPRSLGGHLSKRSYCKPLDGAEIAQELLQSNGQPSLLASMILSTNAVNLQQPQQSTFNPEACFKDPSFLQLLAENRSPAFLPNTFPRSGVTNFNTSVSQEGSEIIKQALETAGIPSTFEGAEMLSHVSTGCVSDASQVNATVMPNPTVPPLLHTVCHPNTLLTNQNRTSNSKTSSIEECSSLPVFPTNDLLLKTVENGLCSSSFPNSGGPSQNFTSNSSRVSVISGPQNTRSSHLNKKGNSASKRRKKVAPPLIAPNASQNLVTSDLTTMGLIAKSVEIPTTNLHSNVIPTCEPQSLVENLTQKLNNVNNQLFMTDVKENFKTSLESHTVLAPLTLKTENGDSQMMALNSCTTSINSDLQISEDNVIQNFEKTLEIIKTAMNSQILEVKSGSQGAGETSQNAQINYNIQLPSVNTVQNNKLPDSSPFSSFISVMPTKSNIPQSEVSHKEDQIQEILEGLQKLKLENDLSTPASQCVLINTSVTLTPTPVKSTADITVIQPVSEMINIQFNDKVNKPFVCQNQGCNYSAMTKDALFKHYGKIHQYTPEMILEIKKNQLKFAPFKCVVPTCTKTFTRNSNLRAHCQLVHHFTTEEMVKLKIKRPYGRKSQSENVPASRSTQVKKQLAMTEENKKESQPALELRAETQNTHSNVAVIPEKQLVEKKSPDKTESSLQVITVTSEQCNTNALTNTQTKGRKIRRHKKEKEEKKRKKPVSQSLEFPTRYSPYRPYRCVHQGCFAAFTIQQNLILHYQAVHKSDLPAFSAEVEEESEAGKESEETETKQTLKEFRCQVSDCSRIFQAITGLIQHYMKLHEMTPEEIESMTASVDVGKFPCDQLECKSSFTTYLNYVVHLEADHGIGLRASKTEEDGVYKCDCEGCDRIYATRSNLLRHIFNKHNDKHKAHLIRPRRLTPGQENMSSKANQEKSKSKHRGTKHSRCGKEGIKMPKTKRKKKNNLENKNAKIVQIEENKPYSLKRGKHVYSIKARNDALSECTSRFVTQYPCMIKGCTSVVTSESNIIRHYKCHKLSKAFTSQHRNLLIVFKRCCNSQVKETSEQEGAKNDVKDSDTCVSESNDNSRTTATVSQKEVEKNEKDEMDELTELFITKLINEDSTSVETQANTSSNVSNDFQEDNLCQSERQKASNLKRVNKEKNVSQNKKRKVEKAEPASAAELSSVRKEEETAVAIQTIEEHPASFDWSSFKPMGFEVSFLKFLEESAVKQKKNTDKDHPNTGNKKGSHSNSRKNIDKTAVTSGNHVCPCKESETFVQFANPSQLQCSDNVKIVLDKNLKDCTELVLKQLQEMKPTVSLKKLEVHSNDPDMSVMKDISIGKATGRGQY", "length": 2723 }, "evidence": [ { "id": "HGNC:18410", "url": "https://alliancegenome.org/gene/HGNC:18410#orthology", "database": "AGR" }, { "id": "MGI:1353423", "url": "https://alliancegenome.org/gene/MGI:1353423#orthology", "database": "AGR" }, { "id": "RGD:61931", "url": "https://alliancegenome.org/gene/RGD:61931#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-9559", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-9559#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2U2-1", "protein_name": "Zinc finger protein 292", "gene_name": "Zfp292", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADDEAEQERLSGGGCAAELRRLGERLQELERRLCESREPAVEAAAAYCRQLCQTLLEYAEKWKTSEDPLPLLEVYTVAIQSYVKARPYLTSECESVALVLERLALSCVELLLCLPVELSDKQWEQFQTLVQVAHETLMESGSCELQFLATLAQETGVWKNAVLSTILSQEPLDKEKVNEFLAFEGPILLDMRIKHLIKTNQLSQATALAKLCSDHPEIGTKGSFKQTYLVCLCTSSPSEKLIEEISEVDCKDALEMICNLESEGDEKSALVLCTAFLSRQLQQGDMYCAWELTLFWSKLQQRVEPSVQVYLERCRQLSLLTKTVYHIFFLIKVINSETEGAGLATCIELCVKALRLESTENTEVKISICKTISCLLPEDLEVKRACQLSEFLIEPTVDAYYAVEMLYNQPDQKYDEENLPIPNSLRCELLLVLKTQWPFDPEFWDWKTLKRQCLALMGEEASIVSSIDELNDSEVYEKVDYQGERGDTSVNGLSAAGLGTDSGLLMDTGDEKQKKKEIKELKDRGFISARFRNWQAYMQYCLLCDKEFLGHRIVRHAQKHYKDGIYSCPICAKNFNSKDSFVPHVTLHVKQSSKERLAAMKPLRRLGRPPKITATHENQKTNINTVAKQEQRPIKKNSLYSTDFIVFNDNDGSDDENDDKDKSYEPEVIPVQKPVPVNEFNCPVTFCKKGFKYFKNLIAHVKGHKDSEDAKRFLEMQSKKVICQYCRRHFVSVTHLNDHLQMHCGSKPYICIQMKCKAGFNSYAELLAHRKEHQVFRAKCLFPKCGRIFSQAYLLYDHEAQHYNTYTCKFTGCGKVYRSQSEMEKHQDGHSHPETGLPPEDQLQPSGNDVNPDSGATAAGGRSENSIDKNLGSNRSADWEKNRAEPAVTKHGQISAAELRQANIPLSNGLETRDNTTVLRTNEVAVSIKVSVNHGVEGDFGKQENLTMEGTGEPLITDVHKPGIGAGVQLCHPGFQEKKGHECLNEAQNSLSNSESLKMDDLNPQSLERQVNTLMTFSVQNEAGLEDNSQICKFECGGDVKTSSSLYDLPLKTLESITFVQSQPDLSSPLGSPSVPPKAPGQKFSCQVEGCTRTYNSSQSIGKHMKTAHPDQYAAFKLQRKTKKGQKSNNLNTPNHGKCVYFLPSQVSSSNHAFFTPQTKANGNPACSAQVQHVSPSIFPAHLASVSAPLLPSVESVLSPNIPSQDKHGQDGILCSQMENLSNAPLPAQMEDLTKTVLPLNIDSGSDPFLPLPTENSSLFSSPADSENNSVFSQLENSTNHYPSQTDGNINSSFLKGGSSENGVFPSQVSSADDFSSTSAQPSTPKKVKKDRGRGPNGKERKPKHNKRAKWPAIIRDGKFICSRCYRAFTNPRSLGGHLSKRSYCKPLDGAEIAQELLQTNRQPSLLASMILSTSAVNMQQPQQSNFNPETCFKDPSFLQLLNVENRPTFLPSTFPRCDVSNFNASVSQEGSEIIKQALETAGIPSTFESAEMLSQVVPIGSVSDAAQVSAAGMPGPPVTPLLQTVCHPNTSPSNQNQTPNSKTLKECNSLPLFTTNDLLLKTIENGLCSNSFSSSTEPPQNFTNNSAHVSVISGPQNTRSSHLNKKGNSASKKRKKVAPAVSVSNTSQNVLPTDLPVGLPAKNLPVPDTNTRSDMTPDCEPRALVENLTQKLNNIDNHLFITDVKENCKASLEPHTMLTPLTLKTENGDSRMMPLSSCTPVNSDLQISEDNVIQNFEKTLEIIKTAMNSQILEVKSGSQGTGETTQNAQINYSMQLPSVNSIPDNKLPDASQCSSFLTVMPTKSEALHKEDQIQDILEGLQNLKLENDTSAPASQSMLMNKSVALSPTPTKSTPNIVVQPVPEVIHVQLNDRVNKPFVCQNQGCNYSAMTKDALFKHYGKIHQYTPEMILEIKKNQLKFAPFKCVVPSCTKTFTRNSNLRAHCQLVHHFTIEEMVKLKIKRPYGRKSQSENLSSPQNNQVKKQPSMAEETKTESQPAFKVPAATGDAALANATVIPEKQLAEKKSPEKPESSSQPVTSSAEQYNANLANLKTKGRKNKRHRKEKEEKREKNPVSQAFELPTKYSSYRPYCCVHQGCFAAFTIQQNLILHYQAVHKSNLPTFSAEVEEESEAVKESEETEPKQSMKEFRCQVSDCSRIFQAITGLIQHYMKLHEMTPEEIESMTAAVDVGKFPCDQLECKLSFTTYLSYVVHLEVDHGIGTRTSKAEEDGIYKCDCEGCDRIYATRSNLLRHIFNKHNDKHKAHLIRPRKLTGQENISSKANQEKSKSKHRTTKPNRSGKDGMKMPKTKRKKKSNLENKSAKVVQIEENKPYSLKRGKHVYSIKARNDALAECTSKFVTQYPCMIKGCTSVVTSESNIIRHYKCHKLSRAFTSQHRNILIVFKRYGNPQGKEISEQEDEKNDKKDPDSSVLEKNDNSEPAAAPQEEGRKGEKDEMDELTELFITKLINEDSTNAENQGNTTLKGNNEFQEHDSCTSERQKPGNLKRVYKEKNTVQSKKRKIDKTEPEVSLVVNNTRKEEEPAVAVQTTEEHPASFDWSSFKPMGFEASFLKFLEESAVKQKKNSDRDHSNSGSKRGSHSSSRRHVDKAAVAGSSHVCSCKDSEIFVQFANPSKLQCSENVKIVLDKTLKDRSELVLKQLQEMKPTVSLKKLEVLSNNPDRTVLKEISIGKATGRGQY", "length": 2698 }, "evidence": [ { "id": "HGNC:18410", "url": "https://alliancegenome.org/gene/HGNC:18410#orthology", "database": "AGR" }, { "id": "MGI:1353423", "url": "https://alliancegenome.org/gene/MGI:1353423#orthology", "database": "AGR" }, { "id": "RGD:61931", "url": "https://alliancegenome.org/gene/RGD:61931#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-9559", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-9559#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5SNV1", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5SNV1", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "Q5SNV1", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5SNV1", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "Q5SNV1", "url": "https://www.uniprot.org/uniprotkb/Q5SNV1" } ], "pmid": "" }, { "name": "regulation of 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"url": "https://www.uniprot.org/uniprotkb/Q5SP48" } ] }, { "name": "yaf2", "type": "synonym", "evidence": [ { "id": "XP_017210591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210591" } ] }, { "name": "zgc:136577", "type": "synonym", "evidence": [ { "id": "XP_017210591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210591" }, { "id": "Q5SP48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SP48" } ] } ], "protein_names": [ { "name": "YY1-associated factor 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017210591", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210591" }, { "id": "Q5SP48", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SP48/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017210591", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210591" } ] }, { "annotation": "May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1.", "evidence": [ { "database": "UniProtKB", "id": "Q5SP48", "url": "https://www.uniprot.org/uniprotkb/Q5SP48#function" }, { "database": "UniProtKB", "id": "ARBA00058221", "url": "https://www.uniprot.org/uniprotkb/ARBA00058221#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5SP48", "url": "https://www.uniprot.org/uniprotkb/Q5SP48" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "yaf2", "url": 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"Protein Classification", "Other" ] }, { "id": "R-DRE-8939243", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8939243", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-8953750", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8953750", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_017210591", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210591", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5SP48", "url": "https://www.uniprot.org/uniprotkb/Q5SP48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5SP48-1", "url": "https://www.uniprot.org/uniprotkb/Q5SP48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041210-115", "url": "https://zfin.org/ZDB-GENE-041210-115", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MADWLFYQPKVPKRQAKPSSDDGYWDCSVCTFKNTAEAFKCMMCDVRKGTSTRKPRPVSQLVSQQVTQQFASATLPKKEKKEKTEKDKNEREPTLKKNNHKKMRPRLKNVDRSSAQHLEVTVGDLTVIITDYKEKTKPSSSSSSSATSADHHSQSGSNSDNTEKGISRSSSPRGEVSSLNGESH", "length": 184, "header": "tr|Q5SP48-1|Q5SP48_DANRE Isoform 1 of YY1-associated factor 2 isoform X1 OS=Danio rerio OX=7955 GN=yaf2 PE=4 SV=1 CANONICAL=Q5SP48-1" }, "isoforms": [ { "isoform_ac": "Q5SP48-1", "url": "https://www.uniprot.org/uniprotkb/Q5SP48/entry#Q5SP48-1", "sequence": { "sequence": "MADWLFYQPKVPKRQAKPSSDDGYWDCSVCTFKNTAEAFKCMMCDVRKGTSTRKPRPVSQLVSQQVTQQFASATLPKKEKKEKTEKDKNEREPTLKKNNHKKMRPRLKNVDRSSAQHLEVTVGDLTVIITDYKEKTKPSSSSSSSATSADHHSQSGSNSDNTEKGISRSSSPRGEVSSLNGESH", "length": 184, "header": "tr|Q5SP48-1|Q5SP48_DANRE Isoform 1 of YY1-associated factor 2 isoform X1 OS=Danio rerio OX=7955 GN=yaf2 PE=4 SV=1 CANONICAL=Q5SP48-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-DRE-8939243", "name": "", 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"categories": [ "Protein Classification" ] }, { "id": "PTHR13334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13334:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13334:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00338", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00338", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5SPH9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5SPH9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DRE-5389840", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5389840", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-5419276", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5419276", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9837999", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9837999", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9937383", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9937383", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5SPH9", "url": "https://www.uniprot.org/uniprotkb/Q5SPH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5SPH9-1", "url": "https://www.uniprot.org/uniprotkb/Q5SPH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040914-39", "url": "https://zfin.org/ZDB-GENE-040914-39", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAASMANFRTLRVLSKIFHGHFTAASAVQHHTACPRLVHTVSVFSPPSPAITESEEPDTLYQRLSVQVKGHDRAVLDSYEFFATLAAKELGLSLEKVFEPPKHIDKLTLLKSRHIFKKHRVQYEMRTHYRCIQISRITGSSARVYLEYIQRNLPEGVAMEVTKTAMEKIPEHIQKPLWDDNKPEASG", "length": 187, "header": "sp|Q5SPH9-1|RT10_DANRE Isoform 1 of Small ribosomal subunit protein uS10m OS=Danio rerio OX=7955 GN=mrps10 PE=3 SV=1 CANONICAL=Q5SPH9-1" }, "isoforms": [ { "isoform_ac": "Q5SPH9-1", "url": "https://www.uniprot.org/uniprotkb/Q5SPH9/entry#Q5SPH9-1", "sequence": { "sequence": "MAASMANFRTLRVLSKIFHGHFTAASAVQHHTACPRLVHTVSVFSPPSPAITESEEPDTLYQRLSVQVKGHDRAVLDSYEFFATLAAKELGLSLEKVFEPPKHIDKLTLLKSRHIFKKHRVQYEMRTHYRCIQISRITGSSARVYLEYIQRNLPEGVAMEVTKTAMEKIPEHIQKPLWDDNKPEASG", "length": 187, "header": "sp|Q5SPH9-1|RT10_DANRE Isoform 1 of Small ribosomal subunit protein uS10m OS=Danio rerio OX=7955 GN=mrps10 PE=3 SV=1 CANONICAL=Q5SPH9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "Q5SPH9", "url": "https://www.uniprot.org/uniprotkb/Q5SPH9" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "R-DRE-5389840", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5389840", "resource": "Reactome", "description": "Mitochondrial translation elongation" }, { "id": "R-DRE-5419276", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5419276", "resource": "Reactome", "description": "Mitochondrial translation termination" }, { "id": "R-DRE-9837999", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9837999", "resource": "Reactome", "description": "Mitochondrial protein degradation" }, { "id": "R-DRE-9937383", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9937383", "resource": "Reactome", "description": "Mitochondrial ribosome-associated quality control" } ], "orthologs": [ { "uniprot_canonical_ac": "P82664-1", "protein_name": "Small ribosomal subunit protein uS10m", "gene_name": "MRPS10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"HGNC:14502", "url": "https://alliancegenome.org/gene/HGNC:14502#orthology", "database": "AGR" }, { "id": "RGD:1311516", "url": "https://alliancegenome.org/gene/RGD:1311516#orthology", "database": "AGR" }, { "id": "MGI:1928139", "url": "https://alliancegenome.org/gene/MGI:1928139#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040914-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040914-39#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80ZK0-1", "protein_name": "Small ribosomal subunit protein uS10m", "gene_name": "Mrps10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKWVPLSNLHVDVPKDVTRPTITTSDEPDTLYKRLSILVKAHDRAVLDSYEYFAVLAAKELGISIKVHEPPRKIERFTLLKSVHIFKKHRVQYEMRTLYRCLELKHLTGSTASVYLEYIQRNLPEGVAMEVTKTQIQQLPEHIKEPMWETVPEEKKESKS", "length": 160 }, "evidence": [ { "id": "FB:FBgn0038307", "url": "https://alliancegenome.org/gene/FB:FBgn0038307#orthology", "database": "AGR" }, { "id": "HGNC:14502", "url": "https://alliancegenome.org/gene/HGNC:14502#orthology", "database": "AGR" }, { "id": "RGD:1311516", "url": "https://alliancegenome.org/gene/RGD:1311516#orthology", "database": "AGR" }, { "id": "MGI:1928139", "url": "https://alliancegenome.org/gene/MGI:1928139#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040914-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040914-39#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VFB2-1", "protein_name": "Small ribosomal subunit protein uS10m", "gene_name": "mRpS10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKMHMKHLDLYSQAIKTLRWTQPMRALSTVNTSSGVQGNLSPAAPAPEPDKLYSKLEIELRGIDPAVLKSYTWFATTAAEHLGIEKGKCWSPRKAHHERMTLLKSVHIYKKHRVQYEVRTHFRYMNFHKLTGSTLDTFLEYIERNLPEGVALQASRTELQEIPEHLRQPPEQV", "length": 173 }, "evidence": [ { "id": "FB:FBgn0038307", "url": "https://alliancegenome.org/gene/FB:FBgn0038307#orthology", "database": "AGR" }, { "id": "HGNC:14502", "url": "https://alliancegenome.org/gene/HGNC:14502#orthology", "database": "AGR" }, { "id": "RGD:1311516", "url": "https://alliancegenome.org/gene/RGD:1311516#orthology", "database": "AGR" }, { "id": "MGI:1928139", "url": "https://alliancegenome.org/gene/MGI:1928139#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040914-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040914-39#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial small ribosomal subunit", "id": "GO:0005763", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005763", "evidence": [ { "database": "UniProtKB", "id": "Q5SPH9", "url": "https://www.uniprot.org/uniprotkb/Q5SPH9" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "Q5SPH9", "url": "https://www.uniprot.org/uniprotkb/Q5SPH9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "Q5SPH9", "url": "https://www.uniprot.org/uniprotkb/Q5SPH9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "Q5SPH9", "url": "https://www.uniprot.org/uniprotkb/Q5SPH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5SPN9-1", "uniprot_ac": "Q5SPN9", "uniprot_id": "Q5SPN9_DANRE", "mass": { "chemical_mass": 7576.0, "monoisotopic_mass": 7576.0 }, "refseq": { "ac": "NP_001116417", "name": "cAMP-dependent protein kinase inhibitor beta", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116417" }, "gene_names": [ { "name": "pkib", "type": "recommended", "evidence": [ { "id": "Q5SPN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SPN9" } ] }, { "name": "im:7054531", "type": "synonym", "evidence": [ { "id": "NP_001116417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116417" }, { "id": "Q5SPN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SPN9" } ] }, { "name": "pkib", "type": "synonym", "evidence": [ { "id": "NP_001116417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116417" } ] }, { "name": "si:dkey-150h13.1", "type": "synonym", "evidence": [ { "id": "NP_001116417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116417" }, { "id": "Q5SPN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SPN9" } ] } ], "protein_names": [ { "name": "cAMP-dependent protein kinase inhibitor", "type": "recommended", "evidence": [ { "id": "Q5SPN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SPN9/entry#names_and_taxonomy" } ] }, { "name": "cAMP-dependent protein kinase inhibitor beta", "type": "synonym", "evidence": [ { "id": "NP_001116417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116417" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC159108.1, GDQH01032406.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1, EH444643.1 and BC133889.1. On or before Apr 2, 2008 this sequence version replaced XP_001336061.1, XP_001336155.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001116417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116417" } ] }, { "annotation": "Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.", "evidence": [ { "database": "UniProtKB", "id": "Q5SPN9", "url": "https://www.uniprot.org/uniprotkb/Q5SPN9#function" }, { "database": "UniProtKB", "id": "ARBA00002844", "url": "https://www.uniprot.org/uniprotkb/ARBA00002844#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5SPN9", "url": "https://www.uniprot.org/uniprotkb/Q5SPN9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "pkib", "url": "https://www.uniprot.org/uniprotkb/Q5SPN9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041014-312", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-312", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000053110", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000053110", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "797348", "url": "https://www.ncbi.nlm.nih.gov/gene/797348", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:797348", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797348", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YQDVAMR", "url": "https://omabrowser.org/oma/group/YQDVAMR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5SPN9", "url": "https://www.orthodb.org/?gene=Q5SPN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02827", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02827", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001116417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116417", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5SPN9", "url": "https://www.uniprot.org/uniprotkb/Q5SPN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5SPN9-1", "url": "https://www.uniprot.org/uniprotkb/Q5SPN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041014-312", "url": "https://zfin.org/ZDB-GENE-041014-312", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTDVEPVVSDFAATGRTGRRNALPDILGSTAGPGAADLPDKLAELTVGDDGEQGGESSSSTDPPKESTEGAKTEGS", "length": 76, "header": "tr|Q5SPN9-1|Q5SPN9_DANRE Isoform 1 of cAMP-dependent protein kinase inhibitor OS=Danio rerio OX=7955 GN=pkib PE=3 SV=1 CANONICAL=Q5SPN9-1" }, "isoforms": [ { "isoform_ac": "Q5SPN9-1", "url": "https://www.uniprot.org/uniprotkb/Q5SPN9/entry#Q5SPN9-1", "sequence": { "sequence": "MTDVEPVVSDFAATGRTGRRNALPDILGSTAGPGAADLPDKLAELTVGDDGEQGGESSSSTDPPKESTEGAKTEGS", "length": 76, "header": "tr|Q5SPN9-1|Q5SPN9_DANRE Isoform 1 of cAMP-dependent protein kinase inhibitor OS=Danio rerio OX=7955 GN=pkib PE=3 SV=1 CANONICAL=Q5SPN9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish gene map defines ancestral vertebrate chromosomes.", "journal": "Genome Res.", "date": "2005", "authors": "Woods Ian G, Wilson Catherine, Friedlander Brian, Chang Patricia, Reyes Daengnoy K, Nix Rebecca, Kelly Peter D, Chu Felicia, Postlethwait John H, Talbot William S", "evidence": [ { "database": "UniProtKB", "id": "Q5SPN9", "url": "https://www.uniprot.org/uniprotkb/Q5SPN9" } ], "reference": [ { "type": "PubMed", "id": "16109975", "url": "https://glygen.org/publication/PubMed/16109975" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "Q5SPN9", "url": "https://www.uniprot.org/uniprotkb/Q5SPN9" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:797348", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797348", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YH48-1", "protein_name": "Protein kinase (cAMP-dependent, catalytic) inhibitor beta", "gene_name": "PKIB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTDVEPLVTDFAASGRAGRRNALPDILGSPAGAGTSDLPHKLAELSVSEGNEGAEGGEVSSSKALLESQEAEGKSNNS", "length": 78 }, "evidence": [ { "id": "Q5SPN9", "url": "https://omabrowser.org/oma/group/Q5SPN9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7FBB8-1", "protein_name": "cAMP-dependent protein kinase inhibitor beta isoform X1", "gene_name": "Pkib", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDKNLDDLGGQKETSDSSKGSDSPGSQQDAVMRTDSSEMTDVESVISTFAASARAGRRNALADIQTLDVTGGTSDLPLKLEALTVKEDVKKKNEEKAQDQPEKTLNEEK", "length": 109 }, "evidence": [ { "id": "Q5SPN9", "url": "https://omabrowser.org/oma/group/Q5SPN9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1SF58-1", "protein_name": "cAMP-dependent protein kinase inhibitor", "gene_name": "PKIB", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { 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"sequence": "MGGGTSPEAQQDSVMRTDSSEMTDVESVITSFASSARAGRRNALPDIQSSLATSGSSDLPLKLEALAVKEDAKTKNEEKDQGQPKTPLNEGK", "length": 92 }, "evidence": [ { "id": "HGNC:9018", "url": "https://alliancegenome.org/gene/HGNC:9018#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C010-1", "protein_name": "cAMP-dependent protein kinase inhibitor beta", "gene_name": "PKIB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRTDSSKMTDVESGVANFASSARAGRRNALPDIQSSAATDGTSDLPLKLEALSVKEDAKEKDEKTTQDQLEKPQNEEK", "length": 78 }, "evidence": [ { "id": "HGNC:9018", "url": "https://alliancegenome.org/gene/HGNC:9018#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-312", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-312#orthology", "database": "AGR" }, { "id": "Q5SPN9", "url": "https://omabrowser.org/oma/group/Q5SPN9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { 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The reference sequence was derived from JBMGRA010000018.1. On Jun 18, 2025 this sequence version replaced NP_001018624.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001018624", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018624" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TKT2", "url": "https://www.uniprot.org/uniprotkb/Q5TKT2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "il17c", "url": "https://www.uniprot.org/uniprotkb/Q5TKT2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061031-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061031-5", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000057180", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000057180", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "553960", "url": "https://www.ncbi.nlm.nih.gov/gene/553960", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:553960", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553960", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VENADMY", "url": "https://omabrowser.org/oma/group/VENADMY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5TKT2", "url": "https://www.orthodb.org/?gene=Q5TKT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF06083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001018624", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018624", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5TKT2", "url": "https://www.uniprot.org/uniprotkb/Q5TKT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TKT2-1", "url": "https://www.uniprot.org/uniprotkb/Q5TKT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061031-5", "url": "https://zfin.org/ZDB-GENE-061031-5", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MWSPLFFGLLFFWLSESKVEGKHLCFKDCDHGFSKAHQKLLRSLISPRHPPVQPVHHPAGSCEDFVRTASDDLKHRSLSPWRTSISLVFFRTVENPDMYPSKYEEAQCLCDGCIINGELNRSYNSVPVFKTHVFLKKHPCPSDPDKYSFTFEHVQVPVACTCAVPKQ", "length": 167, "header": "tr|Q5TKT2-1|Q5TKT2_DANRE Isoform 1 of Interleukin-17C precursor OS=Danio rerio OX=7955 GN=il17c PE=3 SV=1 CANONICAL=Q5TKT2-1" }, "isoforms": [ { "isoform_ac": "Q5TKT2-1", "url": "https://www.uniprot.org/uniprotkb/Q5TKT2/entry#Q5TKT2-1", "sequence": { "sequence": "MWSPLFFGLLFFWLSESKVEGKHLCFKDCDHGFSKAHQKLLRSLISPRHPPVQPVHHPAGSCEDFVRTASDDLKHRSLSPWRTSISLVFFRTVENPDMYPSKYEEAQCLCDGCIINGELNRSYNSVPVFKTHVFLKKHPCPSDPDKYSFTFEHVQVPVACTCAVPKQ", "length": 167, "header": "tr|Q5TKT2-1|Q5TKT2_DANRE Isoform 1 of Interleukin-17C precursor OS=Danio rerio OX=7955 GN=il17c PE=3 SV=1 CANONICAL=Q5TKT2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification, cloning and characterization of interleukin-17 and its family from zebrafish.", "journal": "Fish Shellfish Immunol.", "date": "2006", "authors": "Gunimaladevi I, Savan Ram, Sakai Masahiro", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT2", "url": "https://www.uniprot.org/uniprotkb/Q5TKT2" } ], "reference": [ { "type": "PubMed", "id": "16677828", "url": "https://glygen.org/publication/PubMed/16677828" } ] }, { "title": "Interleukin-17D in Atlantic salmon (Salmo salar): molecular characterization, 3D modelling and promoter analysis.", "journal": "Fish Shellfish Immunol.", "date": "2009", "authors": "Kumari Jaya, Larsen Atle Noralf, Bogwald Jarl, Dalmo Roy A", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT2", "url": "https://www.uniprot.org/uniprotkb/Q5TKT2" } ], "reference": [ { "type": "PubMed", "id": "19716422", "url": "https://glygen.org/publication/PubMed/19716422" } ] }, { "title": "Topographical distribution of antimicrobial genes in the zebrafish intestine.", "journal": "Dev. Comp. Immunol.", "date": "2011", "authors": "Oehlers Stefan H, Flores Maria Vega, Chen Tony, Hall Chris J, Crosier Kathryn E, Crosier Philip S", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT2", "url": "https://www.uniprot.org/uniprotkb/Q5TKT2" } ], "reference": [ { "type": "PubMed", "id": "21093479", "url": "https://glygen.org/publication/PubMed/21093479" } ] }, { "title": "Insights into the antibacterial and immunomodulatory functions of the antimicrobial peptide, epinecidin-1, against Vibrio vulnificus infection in zebrafish.", "journal": "Fish Shellfish Immunol.", "date": "2011", "authors": "Pan Chieh-Yu, Wu Jen-Leih, Hui Cho-Fat, Lin Cheng-Hui, Chen Jyh-Yih", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT2", "url": "https://www.uniprot.org/uniprotkb/Q5TKT2" } ], "reference": [ { "type": "PubMed", "id": "21925271", "url": "https://glygen.org/publication/PubMed/21925271" } ] }, { "title": "Understanding the complexity of epimorphic regeneration in zebrafish caudal fin tissue: A transcriptomic and proteomic approach.", "journal": "Genomics", "date": "2022", "authors": "Banu Sarena, Gaur Namami, Nair Sowmya, Ravikrishnan Tanuja, Khan Shahida, Mani Sandhya, Bharathi Swarna, Mandal Komal, Kuram Naga Anusha, Vuppaladadium Sowmya, Ravi Rowmika, Murthy Ch Lakshmi N, Quoseena Mir, Babu Nukala Sarath, Idris Mohammed M", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT2", "url": "https://www.uniprot.org/uniprotkb/Q5TKT2" } ], "reference": [ { "type": "PubMed", "id": "35134499", "url": "https://glygen.org/publication/PubMed/35134499" } ] } ], "pathway": [ { "id": "dre:553960", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553960", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LTN0-1", "protein_name": "Interleukin-17C", "gene_name": "Il17c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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The reference sequence was derived from AB195256.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001018623", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018623" } ] } ], "disease": [ { "disease_id": "DOID:0050169", "recommended_name": { "id": "DOID:0050169", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050169", "name": "cutaneous lupus erythematosus", "description": "A lupus erythematosus that causes skin lesions on parts of the body that are exposed to sunlight." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050169", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050169" } ] }, { "disease_id": "DOID:0060180", "recommended_name": { "id": "DOID:0060180", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060180", "name": "colitis", "description": "An inflammatory bowel disease that involves inflammation located_in colon." }, "synonyms": [], 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"childhood-onset asthma", "description": "A chronic asthma that is characterized by first presentation in early childhood." }, "synonyms": [ { "id": "DOID:0080815", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080815", "name": "childhood asthma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080815", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080815" } ] }, { "disease_id": "DOID:0080998", "recommended_name": { "id": "DOID:0080998", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080998", "name": "acute necrotizing pancreatitis", "description": "An acute pancreatitis that is characterized by one or more areas of necrosis in the pancreas with varying degree of involvement of the surrounding tissues or organ systems." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0080998", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080998" } ] }, { "disease_id": "DOID:1024", "recommended_name": { "id": "DOID:1024", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1024", "name": "leprosy", "description": "A primary bacterial infectious disease that results_in infection located_in superficial peripheral nerves, located_in skin, located_in mucous membranes of the upper respiratory tract, located_in anterior chamber of the eyes, or located_in testes, has_material_basis_in Mycobacterium leprae, which is transmitted_by aerosol spread from infected nasal secretions to exposed nasal and oral mucosa. The infection has_symptom skin lesions, has_symptom sensory loss, has_symptom motor loss and has_symptom eye damage." }, "synonyms": [ { "id": "MONDO:0011860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011860", "name": "leprosy, susceptibility to, 2", "description": "" }, { "id": "MONDO:0011860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011860", "name": "LPRS2", "description": "" }, { "id": "MONDO:0011860", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011860", "name": "leprosy, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012358", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012358", "name": "leprosy, susceptibility to, 1", "description": "" }, { "id": "MONDO:0012358", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012358", "name": "LPRS1", "description": "" }, { "id": "MONDO:0012358", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012358", "name": "leprosy, paucibacillary type, susceptibility to", "description": "" }, { "id": "MONDO:0012358", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012358", "name": "leprosy, susceptibility to, 1", "description": "" }, { "id": "MONDO:0013257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013257", "name": "leprosy, susceptibility to, 6", "description": "" }, { "id": "MONDO:0013257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013257", "name": "LPRS6", "description": "" }, { "id": "MONDO:0013257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013257", "name": "leprosy, susceptibility to, 6", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1024", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1024" } ] }, { "disease_id": "DOID:10247", "recommended_name": { "id": "DOID:10247", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10247", "name": "pleurisy", "description": "A pleural disease that is characterized by inflammation of the pleura, the lining of the pleural cavity surrounding the lungs." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "10247", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10247" } ] }, { "disease_id": "DOID:1025", "recommended_name": { "id": "DOID:1025", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1025", "name": "tuberculoid leprosy", "description": "A leprosy that results in one erythematous large plaque with well-defined borders that are elevated and that slope down into an atrophic center." }, "synonyms": [ { "id": "DOID:1025", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1025", "name": "Smooth leprosy", "description": "" }, { "id": "DOID:1025", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1025", "name": "type T leprosy", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1025", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1025" } ] }, { "disease_id": "DOID:10316", "recommended_name": { "id": "DOID:10316", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10316", "name": "pneumoconiosis", "description": "An interstitial lung disease that is caused by the inhalation of dust." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "10316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10316" } ] }, { "disease_id": "DOID:10325", "recommended_name": { "id": "DOID:10325", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10325", "name": "silicosis", "description": "A pneumoconiosis that is an inflammation and scarring of the upper lobes of the lungs causing nodular lesions resulting from inhalation of silica, quartz or slate particles." }, "synonyms": [ { "id": "DOID:10325", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10325", "name": "Pneumoconiosis due to silicates", "description": "" }, { "id": "DOID:10325", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10325", "name": "Silica pneumoconiosis", "description": "" }, { "id": "DOID:10325", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10325", "name": "Silicotic fibrosis of lung", "description": "" }, { "id": "DOID:10325", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10325", "name": "silicotuberculosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10325", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10325" } ] }, { "disease_id": "DOID:10763", "recommended_name": { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries." }, "synonyms": [ { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "HTN", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hyperpiesia", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "vascular hypertensive disorder", "description": "" } ], "unlinked_id_list": [ "DOID:13731", "DOID:11130" ], "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ] }, { "disease_id": "DOID:10887", "recommended_name": { "id": "DOID:10887", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10887", "name": "lepromatous leprosy", "description": "A leprosy that results in early cutaneous lesions which consist of pale macules that are small, diffuse, and symmetric. This form of leprosy is characterized by hypoesthesia over extensor surfaces of the distal extremities, alopecia affecting lateral aspects of the eyebrows, saddle-nose deformity and oral lepromas." }, "synonyms": [ { "id": "DOID:10887", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10887", "name": "type L leprosy", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10887", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10887" } ] }, { "disease_id": "DOID:10966", "recommended_name": { "id": "DOID:10966", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10966", "name": "lipoid nephrosis", "description": "" }, "synonyms": [ { "id": "DOID:10966", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10966", "name": "Minimal Change Glomerulonephritis", "description": "" }, { "id": "DOID:10966", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10966", "name": "Minimal change disease", "description": "" }, { "id": "DOID:10966", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10966", "name": "Nephrotic syndrome with lesion of minimal change glomerulonephritis", "description": "" }, { "id": "DOID:10966", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10966", "name": "Nephrotic syndrome with lesion of minimal change nephrotic syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10966", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10966" } ] }, { "disease_id": "DOID:11265", "recommended_name": { "id": "DOID:11265", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11265", "name": "trachoma", "description": "A commensal bacterial infectious disease that results_in infection located_in eye, has_material_basis_in Chlamydia trachomatis (A, B, Ba and C serovars), which is transmitted_by contact with eye discharge from the infected person and transmitted_by congenital method. The infection causes eyelid to turn inward which makes eyelashes to scratch the cornea." }, "synonyms": [ { "id": "DOID:11265", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11265", "name": "active stage trachoma", "description": "" }, { "id": "DOID:11265", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11265", "name": "trachoma dubium", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "11265", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11265" } ] }, { "disease_id": "DOID:12306", "recommended_name": { "id": "DOID:12306", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12306", "name": "vitiligo", "description": "An autoimmune disease that causes depigmentation of patches of skin resulting from loss of function or death of melanoctyes." }, "synonyms": [ { "id": "MONDO:0700077", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700077", "name": "vitiligo-associated multiple autoimmune disease susceptibility 6", "description": "" }, { "id": "MONDO:0700077", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700077", "name": "VAMAS6", "description": "" }, { "id": "MIM:193200", "resource": "MIM", "url": "https://www.omim.org/entry/193200", "name": "Vitiligo", "description": "Vitiligo" } ], "unlinked_id_list": [], "evidence": [ { "id": "12306", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12306" } ] }, { "disease_id": "DOID:12361", "recommended_name": { "id": "DOID:12361", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12361", "name": "Graves' disease", "description": "An autoimmune disease of endocrine system that involves production of excessive amount of thyroid hormones, located_in thyroid gland." }, "synonyms": [ { "id": "DOID:12361", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12361", "name": "Grave's disease", "description": "" }, { "id": "DOID:12361", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12361", "name": "Graves disease", "description": "" }, { "id": "DOID:12361", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12361", "name": "exophthalmic goiter", "description": "" }, { "id": "MONDO:0100489", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100489", "name": "Graves disease, susceptibility to, 1", "description": "" }, { "id": "MONDO:0100489", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100489", "name": "Graves disease, susceptibility to, 1", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12361", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12361" } ] }, { "disease_id": "DOID:1273", "recommended_name": { "id": "DOID:1273", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1273", "name": "respiratory syncytial virus infectious disease", "description": "A viral infectious disease that results_in infection located_in upper respiratory tract or located_in lower respiratory tract, has_material_basis_in Human respiratory syncytial virus (Orthopneumovirus hominis), which is transmitted_by droplet spread of nasal secretions from an infected person while coughing or sneezing, or transmitted_by contaminated fomites. The infection has_symptom runny nose, has_symptom fever, has_symptom cough, has_symptom wheezing, and has_symptom respiratory distress." }, "synonyms": [ { "id": "DOID:1273", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1273", "name": "RSV", "description": "" }, { "id": "DOID:1273", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1273", "name": "respiratory syncytial virus", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1273", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1273" } ] }, { "disease_id": "DOID:13141", "recommended_name": { "id": "DOID:13141", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13141", "name": "uveitis", "description": "An uveal disease is characterized by inflammation of any of the layers of the uvea of the eye, which includes the iris, ciliary body, and choroid." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "13141", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13141" } ] }, { "disease_id": "DOID:13241", "recommended_name": { "id": "DOID:13241", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13241", "name": "Behcet's disease", "description": "An autoimmune disease that is characterized by mucocutaneous manifestations, including recurrent oral and genital ulcerations, ocular manifestations, especially chronic relapsing uveitis, and systemic vasculitis involving arteries and veins of all sizes." }, "synonyms": [ { "id": "DOID:13241", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13241", "name": "Adamantiades-Behcet disease", "description": "" }, { "id": "DOID:13241", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13241", "name": "Behcet syndrome", "description": "" }, { "id": "DOID:13241", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13241", "name": "Behet's syndrome", "description": "" }, { "id": "DOID:13241", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13241", "name": "triple symptom complex", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "Behcet disease", "description": "A chronic, relapsing, multisystemic vasculitis characterized by mucocutaneous lesions, as well as articular, vascular, ocular and central nervous system manifestations." }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "Bechet syndrome", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "Behcet disease", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "Behcet syndrome", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "Behcet's syndrome", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "Behet disease", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "Behet syndrome", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "Behet's syndrome", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "Behet-Adamantiades syndrome", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "Morbus Behet's syndrome", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "silk road disease", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "BD", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "Behet's disease", "description": "" }, { "id": "MONDO:0007191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007191", "name": "Behets disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13241", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13241" } ] }, { "disease_id": "DOID:13375", "recommended_name": { "id": "DOID:13375", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13375", "name": "temporal arteritis", "description": "A central nervous system vasculitis that is characterized by inflammation of the lining of arteries, often arteries in the head." }, "synonyms": [ { "id": "DOID:13375", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13375", "name": "Horton's disease", "description": "" }, { "id": "DOID:13375", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13375", "name": "giant cell arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "temporal arteritis", "description": "A large vessel vasculitis predominantly involving the arteries originating from the aortic arch and especially the extracranial branches of the carotid arteries." }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Giant Cell Arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Horton disease", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "giant cell arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "inflammation of temporal artery", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "temporal arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "temporal artery inflammation", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "GCA", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Horton's arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Horton's giant cell arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Horton's temporal arteritis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Hortons disease", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "Hortons syndrome", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "arteritis cranialis", "description": "" }, { "id": "MONDO:0008538", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008538", "name": "arteritis temporalis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13375", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13375" } ] }, { "disease_id": "DOID:1485", "recommended_name": { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs." }, "synonyms": [ { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "CF", "description": "" }, { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "mucoviscidosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis", "description": "Autosomal recessive disorder caused by pathogenic variants in the CFTR gene (cystic fibrosis transmembrane conductance regulator), which encodes a chloride and bicarbonate channel expressed in epithelial cells, and follow the diagnosis criteria. Diagnosis requires evidence of CFTR dysfunction, defined as a sweat chloride concentration of 60 mmol/L or greater, or identification of two CF-causing CFTR pathogenic variants, or an abnormal nasal potential difference measurement. CF is a progressive, multi-organ disease characterized by chronic obstructive lung disease with recurrent infections, exocrine pancreatic insufficiency, intestinal obstruction (including meconium ileus in neonates), male infertility due to obstructive azoospermia, hepatobiliary complications, and elevated sweat chloride concentrations." }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "CF", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis lung disease, modifier of", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "mucoviscidosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "pseudomonas aeruginosa, susceptibility to chronic infection by, in cystic fibrosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "fibrocystic disease of the pancreas", "description": "" }, { "id": "MIM:219700", "resource": "MIM", "url": "https://www.omim.org/entry/219700", "name": "Cystic fibrosis", "description": "Cystic fibrosis" } ], "unlinked_id_list": [], "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ] }, { "disease_id": "DOID:1580", "recommended_name": { "id": "DOID:1580", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1580", "name": "diffuse scleroderma", "description": "" }, "synonyms": [ { "id": "DOID:1580", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1580", "name": "diffuse systemic sclerosis", "description": "" }, { "id": "DOID:1580", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1580", "name": "systemic sclerosis, diffuse", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1580", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1580" } ] }, { "disease_id": "DOID:2058", "recommended_name": { "id": "DOID:2058", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2058", "name": "chronic mucocutaneous candidiasis", "description": "A candidiasis that refers to a heterogeneous group of disorders characterized by recurrent or persistent superficial fungal infections located_in skin, located_in mucous membrane, or located_in nail due to T-cell defects, has-agent Candida species and has_symptom scaling of skin lesions, has_symptom thickening of nails, has_symptom swollen periungal tissue, and has_symptom scarring of the scalp." }, "synonyms": [ { "id": "MONDO:0007257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007257", "name": "candidiasis, familial, 1", "description": "" }, { "id": "MONDO:0007257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007257", "name": "CANDF1", "description": "" }, { "id": "MONDO:0007257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007257", "name": "candidiasis, familial, 1", "description": "" }, { "id": "MONDO:0007257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007257", "name": "candidiasis, familial, 1, autosomal dominant", "description": "" }, { "id": "MONDO:0008905", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008905", "name": "predisposition to invasive fungal disease due to CARD9 deficiency", "description": "" }, { "id": "MONDO:0008905", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008905", "name": "candidiasis, familial, 2, autosomal recessive", "description": "" }, { "id": "MONDO:0008905", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008905", "name": "candidiasis, familial, type 2", "description": "" }, { "id": "MONDO:0008905", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008905", "name": "invasive candidiasis-deep dermatophytosis syndrome", "description": "" }, { "id": "MONDO:0008905", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008905", "name": "CANDF2", "description": "" }, { "id": "MONDO:0008905", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008905", "name": "CARD9 deficiency", "description": "" }, { "id": "MONDO:0008905", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008905", "name": "candidiasis familial chronic mucocutaneous, autosomal recessive", "description": "" }, { "id": "MONDO:0008905", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008905", "name": "candidiasis, familial, 2", "description": "" }, { "id": "MONDO:0011880", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011880", "name": "candidiasis, familial, 3", "description": "" }, { "id": "MONDO:0011880", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011880", "name": "CANDF3", "description": "" }, { "id": "MONDO:0011880", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011880", "name": "candidiasis, familial, 3", "description": "" }, { "id": "MONDO:0013140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013140", "name": "candidiasis, familial, 4", "description": "Any familial chronic mucocutaneous candidiasis in which the cause of the disease is a mutation in the CLEC7A gene." }, { "id": "MONDO:0013140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013140", "name": "CLEC7A familial chronic mucocutaneous candidiasis", "description": "" }, { "id": "MONDO:0013140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013140", "name": "candidiasis, familial, 4", "description": "" }, { "id": "MONDO:0013140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013140", "name": "candidiasis, familial, 4, autosomal recessive", "description": "" }, { "id": "MONDO:0013140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013140", "name": "candidiasis, familial, type 4", "description": "" }, { "id": "MONDO:0013140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013140", "name": "familial chronic mucocutaneous candidiasis caused by mutation in CLEC7A", "description": "" }, { "id": "MONDO:0013140", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013140", "name": "CANDF4", "description": "" }, { "id": "MONDO:0013503", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013503", "name": "candidiasis, familial, 6", "description": "Any familial chronic mucocutaneous candidiasis in which the cause of the disease is a mutation in the IL17F gene." }, { "id": "MONDO:0013503", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013503", "name": "IL17F familial chronic mucocutaneous candidiasis", "description": "" }, { "id": "MONDO:0013503", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013503", "name": "candidiasis, familial, 6", "description": "" }, { "id": "MONDO:0013503", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013503", "name": "candidiasis, familial, 6, autosomal dominant", "description": "" }, { "id": "MONDO:0013503", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013503", "name": "candidiasis, familial, type 6", "description": "" }, { "id": "MONDO:0013503", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013503", "name": "familial chronic mucocutaneous candidiasis caused by mutation in IL17F", "description": "" }, { "id": "MONDO:0013503", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013503", "name": "CANDF6", "description": "" }, { "id": "MONDO:0014230", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014230", "name": "candidiasis, familial, 8", "description": "Any chronic mucocutaneous candidiasis in which the cause of the disease is a mutation in the TRAF3IP2 gene." }, { "id": "MONDO:0014230", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014230", "name": "TRAF3IP2 chronic mucocutaneous candidiasis (disease)", "description": "" }, { "id": "MONDO:0014230", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014230", "name": "candidiasis, familial, 8", "description": "" }, { "id": "MONDO:0014230", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014230", "name": "candidiasis, familial, type 8", "description": "" }, { "id": "MONDO:0014230", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014230", "name": "chronic mucocutaneous candidiasis (disease) caused by mutation in TRAF3IP2", "description": "" }, { "id": "MONDO:0014230", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014230", "name": "CANDF8", "description": "" }, { "id": "MONDO:0014642", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014642", "name": "candidiasis, familial, 9", "description": "Any chronic mucocutaneous candidiasis in which the cause of the disease is a mutation in the IL17RC gene." }, { "id": "MONDO:0014642", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014642", "name": "IL17RC chronic mucocutaneous candidiasis (disease)", "description": "" }, { "id": "MONDO:0014642", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014642", "name": "candidiasis, familial, 9", "description": "" }, { "id": "MONDO:0014642", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014642", "name": "candidiasis, familial, type 9", "description": "" }, { "id": "MONDO:0014642", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014642", "name": "chronic mucocutaneous candidiasis (disease) caused by mutation in IL17RC", "description": "" }, { "id": "MONDO:0014642", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014642", "name": "CANDF9", "description": "" }, { "id": "MIM:212050", "resource": "MIM", "url": "https://www.omim.org/entry/212050", "name": "Immunodeficiency 103, susceptibility to fungal infections", "description": "Immunodeficiency 103, susceptibility to fungal infections" }, { "id": "MIM:613108", "resource": "MIM", "url": "https://www.omim.org/entry/613108", "name": "Candidiasis, familial, 4", "description": "Candidiasis, familial, 4" }, { "id": "MIM:613956", "resource": "MIM", "url": "https://www.omim.org/entry/613956", "name": "Candidiasis, familial, 6", "description": "Candidiasis, familial, 6" }, { "id": "MIM:615527", "resource": "MIM", "url": "https://www.omim.org/entry/615527", "name": "Candidiasis, familial, 8", "description": "Candidiasis, familial, 8" }, { "id": "MIM:616445", "resource": "MIM", "url": "https://www.omim.org/entry/616445", "name": "Candidiasis, familial, 9", "description": "Candidiasis, familial, 9" } ], "unlinked_id_list": [], "evidence": [ { "id": "2058", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2058" } ] }, { "disease_id": "DOID:2316", "recommended_name": { "id": "DOID:2316", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2316", "name": "brain ischemia", "description": "An ischemia that is characterized by insufficient blood flow to the brain to meet metabolic demand." }, "synonyms": [ { "id": "DOID:2316", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2316", "name": "Ischaemic encephalopathy", "description": "" }, { "id": "DOID:2316", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2316", "name": "Ischemic encephalopathy", "description": "" }, { "id": "DOID:2316", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2316", "name": "cerebral ischemia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2316", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2316" } ] }, { "disease_id": "DOID:2377", "recommended_name": { "id": "DOID:2377", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring." }, "synonyms": [ { "id": "DOID:2377", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2377", "name": "Generalized multiple sclerosis", "description": "" }, { "id": "DOID:2377", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2377", "name": "insular sclerosis", "description": "" }, { "id": "MONDO:0012956", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012956", "name": "multiple sclerosis, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012956", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012956", "name": "MS2", "description": "" }, { "id": "MONDO:0012956", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012956", "name": "multiple sclerosis, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012957", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012957", "name": "multiple sclerosis, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012957", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012957", "name": "MS3", "description": "" }, { "id": "MONDO:0012957", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012957", "name": "multiple sclerosis, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012958", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012958", "name": "multiple sclerosis, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012958", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012958", "name": "MS4", "description": "" }, { "id": "MONDO:0012958", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012958", "name": "multiple sclerosis, susceptibility to, 4", "description": "" }, { "id": "MIM:612595", "resource": "MIM", "url": "https://www.omim.org/entry/612595", "name": "Multiple sclerosis 3", "description": "Multiple sclerosis 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ] }, { "disease_id": "DOID:2755", "recommended_name": { "id": "DOID:2755", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2755", "name": "Mycobacterium avium complex disease", "description": "A primary bacterial infectious disease that results_in infection, has_material_basis_in Mycobacterium avium complex (MAC), which is transmitted_by inhalation or transmitted_by ingestion of via the respiratory or gastrointestinal tract respectively. The bacteria cause disseminated infection in HIV infected people, while pulmonary disease in immunocompetent persons." }, "synonyms": [ { "id": "DOID:2755", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2755", "name": "Infection due to Mycobacterium intracellulare", "description": "" }, { "id": "DOID:2755", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2755", "name": "MAC disease", "description": "" }, { "id": "DOID:2755", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2755", "name": "Mycobacterium Avium Infection", "description": "" }, { "id": "DOID:2755", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2755", "name": "Mycobacterium avium Complex", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2755", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2755" } ] }, { "disease_id": "DOID:2841", "recommended_name": { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing." }, "synonyms": [ { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "bronchial hyperreactivity", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with acute exacerbation", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with status asthmaticus", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "inherited susceptibility to asthma", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, nocturnal, susceptibility to", "description": "" }, { "id": "MIM:600807", "resource": "MIM", "url": "https://www.omim.org/entry/600807", "name": "Asthma", "description": "Asthma" } ], "unlinked_id_list": [ "DOID:0080811", "DOID:0080819" ], "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ] }, { "disease_id": "DOID:2942", "recommended_name": { "id": "DOID:2942", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2942", "name": "bronchiolitis", "description": "A lung disease that is an inflammation of the bronchioles, the smallest air passages of the lungs. It is caused by viruses and bacteria. The disease has_symptom cough, has_symptom wheezing, has_symptom shortness of breath, has_symptom fever, has_symptom nasal flaring in infants and has_symptom bluish skin due to lack of oxygen." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "2942", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2942" } ] }, { "disease_id": "DOID:2957", "recommended_name": { "id": "DOID:2957", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ] }, { "disease_id": "DOID:3083", "recommended_name": { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both." }, "synonyms": [ { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "COLD", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "COPD", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive airway disease", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive lung disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease", "description": "A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema." }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COLD", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COPD", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COPD, chronic obstructive pulmonary disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive airways disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive lung disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease (COPD)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease, (COPD)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "cold", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "cold (chronic obstructive lung disease)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "disease (COPD), chronic obstructive", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "obstructive lung disease, chronic", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "obstructive pulmonary disease (COPD), chronic", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "pulmonary disease (COPD), chronic obstructive", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ] }, { "disease_id": "DOID:3310", "recommended_name": { "id": "DOID:3310", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3310", "name": "atopic dermatitis", "description": "An allergic contact dermatitis that is a chronically relapsing inflammatory allergic response located_in the skin that causes itching and flaking." }, "synonyms": [ { "id": "DOID:3310", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3310", "name": "Atopic neurodermatitis", "description": "" }, { "id": "DOID:3310", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3310", "name": "Besnier's prurigo", "description": "" }, { "id": "DOID:3310", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3310", "name": "allergic dermatitis", "description": "" }, { "id": "DOID:3310", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3310", "name": "atopic eczema", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "atopic eczema", "description": "A common chronic pruritic inflammatory skin disease with a strong genetic component. Onset typically occurs during the first 2 years of life." }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "ATOD", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "allergic form of dermatitis", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "atopic dermatitis", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "atopic eczema", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "dermatitis, atopic", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "eczema", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "eczema, atopic", "description": "" }, { "id": "MONDO:0004980", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0004980", "name": "eczematous dermatitis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3310", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3310" } ] }, { "disease_id": "DOID:3388", "recommended_name": { "id": "DOID:3388", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3388", "name": "periodontal disease", "description": "A mouth disease that is relating to or affecting the structures surrounding and supporting the teeth." }, "synonyms": [ { "id": "DOID:3388", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3388", "name": "disease of supporting structures of teeth", "description": "" }, { "id": "DOID:3388", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3388", "name": "periodontium disorder", "description": "" } ], "unlinked_id_list": [ "DOID:1483", "DOID:3086" ], "evidence": [ { "id": "3388", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3388" } ] }, { "disease_id": "DOID:3482", "recommended_name": { "id": "DOID:3482", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3482", "name": "plague", "description": "A primary bacterial infectious disease that results_in infection, located_in lymph node, located_in vasculature or located_in lungs, has_material_basis_in Yersinia pestis, which is transmitted_by oriental rat flea (Xenopsylla cheopis) infected by feeding on rodents and other mammals, transmitted_by air, transmitted_by direct contact or transmitted_by ingestion of contaminated undercooked food." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "3482", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3482" } ] }, { "disease_id": "DOID:3770", "recommended_name": { "id": "DOID:3770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3770", "name": "pulmonary fibrosis", "description": "An interstitial lung disease that is characterized by destruction, scarring, and thickening of the interstitial lung tissues and progressive pulmonary function loss in a restrictive pattern, has_symptom progressive shortness of breath, fatigue, and chronic cough, possibly has_material_basis_in exposure to certain chemicals, autoimmune conditions, and radiation. It can be caused by inhaling hazardous chemicals, certain diseases, medication and genetics or unknown causes." }, "synonyms": [ { "id": "DOID:3770", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3770", "name": "Fibrosis of lung", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3770", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3770" } ] }, { "disease_id": "DOID:418", "recommended_name": { "id": "DOID:418", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:418", "name": "systemic scleroderma", "description": "A scleroderma that is characterized by fibrosis (or hardening) of the skin and major organs, as well as vascular alterations, and autoantibodies." }, "synonyms": [ { "id": "DOID:418", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:418", "name": "Scleroderma", "description": "" }, { "id": "DOID:418", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:418", "name": "Scleroderma syndrome", "description": "" }, { "id": "DOID:418", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:418", "name": "progressive systemic sclerosis", "description": "" }, { "id": "DOID:418", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:418", "name": "systemic sclerosis", "description": "" }, { "id": "MONDO:0008418", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008418", "name": "scleroderma, familial progressive", "description": "" }, { "id": "MONDO:0008418", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008418", "name": "scleroderma, familial progressive", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "418", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:418" } ] }, { "disease_id": "DOID:4448", "recommended_name": { "id": "DOID:4448", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4448", "name": "macular degeneration", "description": "A retinal degeneration characterized by gradual deterioration of light-sensing cells in the tissues at the back of the eye and has_symptom vision loss." }, "synonyms": [ { "id": "DOID:4448", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4448", "name": "Macular degeneration of retina", "description": "" } ], "unlinked_id_list": [ "DOID:2007", "DOID:0070438" ], "evidence": [ { "id": "4448", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4448" } ] }, { "disease_id": "DOID:4481", "recommended_name": { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "allergic rhinitis", "description": "A rhinitis that is an allergic inflammation and irritation of the nasal airways involving sneezing, runny nose, nasal congestion, itching and tearing of the eyes caused by exposure to an allergen such as pollen, dust, mold, animal dander and droppings of cockroaches or house dust mites." }, "synonyms": [ { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "Non-seasonal allergic rhinitis", "description": "" }, { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "Perenial allergic rhinitis", "description": "" }, { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "atopic rhinitis", "description": "" }, { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "hay fever", "description": "" }, { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "pollenosis", "description": "" }, { "id": "DOID:4481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4481", "name": "seasonal allergic rhinitis", "description": "" }, { "id": "MONDO:0100177", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100177", "name": "allergic rhinitis, susceptibility to", "description": "An inherited susceptibility or predisposition to developing allergic rhinitis." }, { "id": "MONDO:0100177", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100177", "name": "allergic rhinitis, susceptibility to", "description": "" }, { "id": "MIM:607154", "resource": "MIM", "url": "https://www.omim.org/entry/607154", "name": "Allergic rhinitis", "description": "Allergic rhinitis" } ], "unlinked_id_list": [], "evidence": [ { "id": "4481", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4481" } ] }, { "disease_id": "DOID:4483", "recommended_name": { "id": "DOID:4483", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4483", "name": "rhinitis", "description": "A upper respiratory infectious disease which involves irritation and inflammation of the mucous membrane of the nose due to viruses, bacteria or irritants. The inflammation results in generation of excessive amounts of mucus leading to runny nose, as well as nasal congestion and post-nasal drip." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "4483", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4483" } ] }, { "disease_id": "DOID:4780", "recommended_name": { "id": "DOID:4780", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4780", "name": "anti-basement membrane glomerulonephritis", "description": "A Goodpasture syndrome that is characterized by damage to only kidney capillaries." }, "synonyms": [ { "id": "DOID:4780", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4780", "name": "anti-GBM glomerulonephritis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "4780", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4780" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:6000", "recommended_name": { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body." }, "synonyms": [ { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "CHF", "description": "" }, { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "Cardiac Failure Congestive", "description": "" }, { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "Congestive heart disease", "description": "" }, { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "Weak heart", "description": "" } ], "unlinked_id_list": [ "DOID:12326" ], "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ] }, { "disease_id": "DOID:6543", "recommended_name": { "id": "DOID:6543", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6543", "name": "acne", "description": "A sebaceous gland disease characterized by areas of blackheads, whiteheads, pimples, greasy skin, and possibly scarring." }, "synonyms": [ { "id": "DOID:6543", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6543", "name": "Acne varioliformis", "description": "" }, { "id": "DOID:6543", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6543", "name": "acne vulgaris", "description": "" }, { "id": "DOID:6543", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6543", "name": "frontalis acne", "description": "" }, { "id": "MONDO:0100486", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100486", "name": "adult acne", "description": "Acne that occurs in an adult." }, { "id": "MONDO:0100486", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100486", "name": "acne, adult", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "6543", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6543" } ] }, { "disease_id": "DOID:7147", "recommended_name": { "id": "DOID:7147", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7147", "name": "ankylosing spondylitis", "description": "An arthritis that results_in inflammation in the joints of the spine and pelvis. The disease has_symptom pain, has_symptom stiffness in the spine, has_symptom stiffness in the neck, has_symptom stiffness in the hips, has_symptom stiffness in the jaw and has_symptom stiffness in the rib cage." }, "synonyms": [ { "id": "DOID:7147", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7147", "name": "Bekhterev syndrome", "description": "" }, { "id": "DOID:7147", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7147", "name": "Bekhterev's disease", "description": "" }, { "id": "DOID:7147", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7147", "name": "Marie-Strumpell disease", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "spondyloarthropathy, susceptibility to, 1", "description": "Any spondyloarthropathy, susceptibility to in which the cause of the disease is a mutation in the HLA-B gene." }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "HLA-B spondyloarthropathy, susceptibility to", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "spondyloarthropathy, susceptibility to caused by mutation in HLA-B", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "spondyloarthropathy, susceptibility to, 1", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "spondyloarthropathy, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0007126", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007126", "name": "SPDA1", "description": "" }, { "id": "MIM:106300", "resource": "MIM", "url": "https://www.omim.org/entry/106300", "name": "Spondyloarthropathy 1", "description": "Spondyloarthropathy 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "7147", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7147" } ] }, { "disease_id": "DOID:7148", "recommended_name": { "id": "DOID:7148", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7148", "name": "rheumatoid arthritis", "description": "An arthritis that is an autoimmune disease which attacks healthy cells and tissue located_in joint." }, "synonyms": [ { "id": "DOID:7148", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7148", "name": "Arthritis or polyarthritis, rheumatic", "description": "" }, { "id": "DOID:7148", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7148", "name": "atrophic Arthritis", "description": "" }, { "id": "MONDO:0008383", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008383", "name": "rheumatoid arthritis", "description": "A chronic, systemic autoimmune disorder characterized by inflammation in the synovial membranes and articular surfaces. It manifests primarily as a symmetric, erosive polyarthritis that spares the axial skeleton and is typically associated with the presence in the serum of rheumatoid factor." }, { "id": "MONDO:0008383", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008383", "name": "RA", "description": "" }, { "id": "MONDO:0008383", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008383", "name": "rheumatoid arthritis", "description": "" }, { "id": "MIM:180300", "resource": "MIM", "url": "https://www.omim.org/entry/180300", "name": "Rheumatoid arthritis", "description": "Rheumatoid arthritis" } ], "unlinked_id_list": [], "evidence": [ { "id": "7148", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:7148" } ] }, { "disease_id": "DOID:820", "recommended_name": { "id": "DOID:820", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:820", "name": "myocarditis", "description": "An extrinsic cardiomyopathy that is characterized as an inflammation of the heart muscle." }, "synonyms": [ { "id": "DOID:820", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:820", "name": "Myocardial inflammation", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "820", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:820" } ] }, { "disease_id": "DOID:823", "recommended_name": { "id": "DOID:823", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:823", "name": "periapical periodontitis", "description": "" }, "synonyms": [ { "id": "DOID:823", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:823", "name": "Apical periodontitis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "823", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:823" } ] }, { "disease_id": "DOID:8893", "recommended_name": { "id": "DOID:8893", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8893", "name": "psoriasis", "description": "A skin disease that is characterized by patches of thick red skin and silvery scales." }, "synonyms": [ { "id": "MONDO:0008334", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008334", "name": "psoriasis 1, susceptibility to", "description": "Any psoriasis in which the cause of the disease is a mutation in the HLA-C gene." }, { "id": "MONDO:0008334", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008334", "name": "HLA-C psoriasis", "description": "" }, { "id": "MONDO:0008334", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008334", "name": "psoriasis 1, susceptibility to", "description": "" }, { "id": "MONDO:0008334", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008334", "name": "psoriasis caused by mutation in HLA-C", "description": "" }, { "id": "MONDO:0008334", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008334", "name": "psoriasis susceptibility 1", "description": "" }, { "id": "MONDO:0008334", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008334", "name": "PSORS1", "description": "" }, { "id": "MIM:177900", "resource": "MIM", "url": "https://www.omim.org/entry/177900", "name": "Psoriasis 1", "description": "Psoriasis 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "8893", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8893" } ] }, { "disease_id": "DOID:9008", "recommended_name": { "id": "DOID:9008", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9008", "name": "psoriatic arthritis", "description": "An arthritis that is characterized by joint inflammation that usually occurs in combination with psoriasis." }, "synonyms": [ { "id": "DOID:9008", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9008", "name": "arthritis psoriatica", "description": "" }, { "id": "DOID:9008", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9008", "name": "arthropathic psoriasis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9008", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9008" } ] }, { "disease_id": "DOID:9074", "recommended_name": { "id": "DOID:9074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9074", "name": "systemic lupus erythematosus", "description": "A lupus erythematosus that is an inflammation of connective tissue marked by skin rashes, joint pain and swelling, inflammation of the kidneys and inflammation of the tissue surrounding the heart." }, "synonyms": [ { "id": "DOID:9074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9074", "name": "Lupus Erythematosus, systemic", "description": "" }, { "id": "DOID:9074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9074", "name": "SLE - Lupus Erythematosus, systemic", "description": "" }, { "id": "DOID:9074", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9074", "name": "disseminated lupus erythematosus", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "systemic lupus erythematosus", "description": "An autoimmune multi-organ disease typically associated with vasculopathy and autoantibody production. Most patients have antinuclear antibodies (ANA). The presence of anti-dsDNA or anti-Smith antibodies are highly-specific." }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "Lupus", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "SLE", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "SLE - lupus erythematosus, systemic", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "disseminated lupus erythematosus", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "lupus erythematosus, systemic", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "systemic lupus erythematosus", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "systemic lupus erythematosus (disease)", "description": "" }, { "id": "MONDO:0007915", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007915", "name": "systemic lupus erythematosus susceptibility to", "description": "" }, { "id": "MONDO:0010433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010433", "name": "systemic lupus erythematosus, susceptibility to, 15", "description": "" }, { "id": "MONDO:0010433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010433", "name": "SLEB15", "description": "" }, { "id": "MONDO:0010433", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010433", "name": "systemic lupus erythematosus, susceptibility to, 15", "description": "" }, { "id": "MONDO:0011560", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011560", "name": "systemic lupus erythematosus, susceptibility to, 3", "description": "" }, { "id": "MONDO:0011560", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011560", "name": "SLEB3", "description": "" }, { "id": "MONDO:0011560", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011560", "name": "systemic lupus erythematosus, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012036", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012036", "name": "systemic lupus erythematosus, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012036", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012036", "name": "SLEB4", "description": "" }, { "id": "MONDO:0012036", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012036", "name": "systemic lupus erythematosus, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012361", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012361", "name": "systemic lupus erythematosus, susceptibility to, 5", "description": "" }, { "id": "MONDO:0012361", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012361", "name": "SLEB5", "description": "" }, { "id": "MONDO:0012361", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012361", "name": "systemic lupus erythematosus, susceptibility to, 5", "description": "" }, { "id": "MONDO:0012369", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012369", "name": "systemic lupus erythematosus, susceptibility to, 6", "description": "" }, { "id": "MONDO:0012369", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012369", "name": "SLEB6", "description": "" }, { "id": "MONDO:0012369", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012369", "name": "systemic lupus erythematosus, susceptibility to, 6", "description": "" }, { "id": "MONDO:0012403", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012403", "name": "systemic lupus erythematosus, susceptibility to, 7", "description": "" }, { "id": "MONDO:0012403", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012403", "name": "SLEB7", "description": "" }, { "id": "MONDO:0012403", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012403", "name": "systemic lupus erythematosus, susceptibility to, 7", "description": "" }, { "id": "MONDO:0012404", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012404", "name": "systemic lupus erythematosus, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012404", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012404", "name": "SLEB8", "description": "" }, { "id": "MONDO:0012404", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012404", "name": "systemic lupus erythematosus, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012836", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012836", "name": "systemic lupus erythematosus, susceptibility to, 12", "description": "" }, { "id": "MONDO:0012836", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012836", "name": "SLEB12", "description": "" }, { "id": "MONDO:0012836", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012836", "name": "systemic lupus erythematosus, susceptibility to, 12", "description": "" }, { "id": "MONDO:0012884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012884", "name": "systemic lupus erythematosus, susceptibility to, 13", "description": "" }, { "id": "MONDO:0012884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012884", "name": "SLEB13", "description": "" }, { "id": "MONDO:0012884", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012884", "name": "systemic lupus erythematosus, susceptibility to, 13", "description": "" }, { "id": "MONDO:0013152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013152", "name": "systemic lupus erythematosus, susceptibility to, 14", "description": "" }, { "id": "MONDO:0013152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013152", "name": "SLEB14", "description": "" }, { "id": "MONDO:0013152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013152", "name": "systemic lupus erythematosus, susceptibility to, 14", "description": "" }, { "id": "MONDO:0013743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013743", "name": "autosomal systemic lupus erythematosus type 16", "description": "An instance of systemic lupus erythematosus (disease) that is caused by mutations in DNASE1L3." }, { "id": "MONDO:0013743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013743", "name": "SLEB16", "description": "" }, { "id": "MONDO:0013743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013743", "name": "systemic lupus erythematosus 16", "description": "" }, { "id": "MONDO:0013743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013743", "name": "systemic lupus erythematosus related to DNASE1L3", "description": "" }, { "id": "MONDO:0013743", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013743", "name": "systemic lupus erythematosus type 16", "description": "" }, { "id": "MIM:152700", "resource": "MIM", "url": "https://www.omim.org/entry/152700", "name": "Systemic lupus erythematosus", "description": "Systemic lupus erythematosus" }, { "id": "MIM:609939", "resource": "MIM", "url": "https://www.omim.org/entry/609939", "name": "Systemic lupus erythematosus 6", "description": "Systemic lupus erythematosus 6" }, { "id": "MIM:614420", "resource": "MIM", "url": "https://www.omim.org/entry/614420", "name": "Systemic lupus erythematosus 16", "description": "Systemic lupus erythematosus 16" } ], "unlinked_id_list": [], "evidence": [ { "id": "9074", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9074" } ] }, { "disease_id": "DOID:9111", "recommended_name": { "id": "DOID:9111", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9111", "name": "cutaneous leishmaniasis", "description": "A leishmaniasis that involves skin infection caused by Leishmania species, resulting in one or more cutaneous lesions." }, "synonyms": [ { "id": "DOID:9111", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9111", "name": "Asian Desert Cutaneous Leishmaniasis", "description": "" }, { "id": "DOID:9111", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9111", "name": "Leproid leishmaniasis", "description": "" }, { "id": "DOID:9111", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9111", "name": "diffuse cutaneous leishmaniasis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9111", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9111" } ] }, { "disease_id": "DOID:9408", "recommended_name": { "id": "DOID:9408", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9408", "name": "acute myocardial infarction", "description": "" }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "9408", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9408" } ] }, { "disease_id": "DOID:9415", "recommended_name": { "id": "DOID:9415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9415", "name": "allergic asthma", "description": "An extrinsic asthma that is characterized by symptoms that are triggered by an allergic reaction caused by inhaled allergens such as dust mite allergen, pet dander, pollen and mold. The disease has_symptom coughing, has_symptom wheezing, has_symptom shortness of breath or has_symptom rapid breathing, and has_symptom chest tightness." }, "synonyms": [ { "id": "DOID:9415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9415", "name": "extrinsic asthma with acute exacerbation", "description": "" }, { "id": "DOID:9415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9415", "name": "extrinsic asthma with status asthmaticus", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9415", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9415" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TKT4", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "f1", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061031-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061031-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000043933", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000043933", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "553959", "url": "https://www.ncbi.nlm.nih.gov/gene/553959", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020440", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020440", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:553959", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553959", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHYRLES", "url": "https://omabrowser.org/oma/group/CHYRLES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5TKT4", "url": "https://www.orthodb.org/?gene=Q5TKT4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF06083", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06083", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001018623", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018623", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5TKT4", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TKT4-1", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061031-3", "url": "https://zfin.org/ZDB-GENE-061031-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSALNLRFLMVACMMGLVLISFGAEGASVRSDQKNKNSHPEADHSYRLVLDAEFKASTNPIHPINNDSISPWTYMFTHNESLYPTSIAEAKCSLTGCLIDGVEVQDYESKPIYTQIMVLRRIRGEKPNYSFKLEYKTIAVGCTCVRPYVEQL", "length": 153, "header": "tr|Q5TKT4-1|Q5TKT4_DANRE Isoform 1 of Interleukin 17a/f1 precursor OS=Danio rerio OX=7955 GN=f1 PE=3 SV=1 CANONICAL=Q5TKT4-1" }, "isoforms": [ { "isoform_ac": "Q5TKT4-1", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4/entry#Q5TKT4-1", "sequence": { "sequence": "MSSALNLRFLMVACMMGLVLISFGAEGASVRSDQKNKNSHPEADHSYRLVLDAEFKASTNPIHPINNDSISPWTYMFTHNESLYPTSIAEAKCSLTGCLIDGVEVQDYESKPIYTQIMVLRRIRGEKPNYSFKLEYKTIAVGCTCVRPYVEQL", "length": 153, "header": "tr|Q5TKT4-1|Q5TKT4_DANRE Isoform 1 of Interleukin 17a/f1 precursor OS=Danio rerio OX=7955 GN=f1 PE=3 SV=1 CANONICAL=Q5TKT4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification, cloning and characterization of interleukin-17 and its family from zebrafish.", "journal": "Fish Shellfish Immunol.", "date": "2006", "authors": "Gunimaladevi I, Savan Ram, Sakai Masahiro", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT4", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4" } ], "reference": [ { "type": "PubMed", "id": "16677828", "url": "https://glygen.org/publication/PubMed/16677828" } ] }, { "title": "Interleukin-17D in Atlantic salmon (Salmo salar): molecular characterization, 3D modelling and promoter analysis.", "journal": "Fish Shellfish Immunol.", "date": "2009", "authors": "Kumari Jaya, Larsen Atle Noralf, Bogwald Jarl, Dalmo Roy A", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT4", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4" } ], "reference": [ { "type": "PubMed", "id": "19716422", "url": "https://glygen.org/publication/PubMed/19716422" } ] }, { "title": "Adaptive autoimmunity and Foxp3-based immunoregulation in zebrafish.", "journal": "PLoS ONE", "date": "2010", "authors": "Quintana Francisco J, Iglesias Antonio H, Farez Mauricio F, Caccamo Mario, Burns Evan J, Kassam Nasim, Oukka Mohamed, Weiner Howard L", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT4", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4" } ], "reference": [ { "type": "PubMed", "id": "20221429", "url": "https://glygen.org/publication/PubMed/20221429" } ] }, { "title": "Topographical distribution of antimicrobial genes in the zebrafish intestine.", "journal": "Dev. Comp. Immunol.", "date": "2011", "authors": "Oehlers Stefan H, Flores Maria Vega, Chen Tony, Hall Chris J, Crosier Kathryn E, Crosier Philip S", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT4", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4" } ], "reference": [ { "type": "PubMed", "id": "21093479", "url": "https://glygen.org/publication/PubMed/21093479" } ] }, { "title": "Th17-like immune response in fish mucosal tissues after administration of live attenuated Vibrio anguillarum via different vaccination routes.", "journal": "Fish Shellfish Immunol.", "date": "2014", "authors": "Zhang Hua, Shen Binbing, Wu Haizhen, Gao Liang, Liu Qin, Wang Qiyao, Xiao Jingfan, Zhang Yuanxing", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT4", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4" } ], "reference": [ { "type": "PubMed", "id": "24561130", "url": "https://glygen.org/publication/PubMed/24561130" } ] }, { "title": "Deficiency of heat shock factor 4 promotes lens epithelial cell senescence through upregulating p21cip1 expression.", "journal": "Biochim. Biophys. Acta Mol. Basis Dis.", "date": "2021", "authors": "Cui X, Du C, Wan S, Wu D, Yan L, Zhang J, Li J, Li H, Yang Z, Zhang H, Zhang J, Mu H, Zhang F, Peng X, Liu M, Hu Y", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT4", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4" } ], "reference": [ { "type": "PubMed", "id": "34339841", "url": "https://glygen.org/publication/PubMed/34339841" } ] }, { "title": "Protocol for inducing inflammation and acute myelin degeneration in larval zebrafish.", "journal": "STAR Protoc", "date": "2022", "authors": "Jaronen Merja, Wheeler Michael A, Quintana Francisco J", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT4", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4" } ], "reference": [ { "type": "PubMed", "id": "35128477", "url": "https://glygen.org/publication/PubMed/35128477" } ] }, { "title": "Understanding the complexity of epimorphic regeneration in zebrafish caudal fin tissue: A transcriptomic and proteomic approach.", "journal": "Genomics", "date": "2022", "authors": "Banu Sarena, Gaur Namami, Nair Sowmya, Ravikrishnan Tanuja, Khan Shahida, Mani Sandhya, Bharathi Swarna, Mandal Komal, Kuram Naga Anusha, Vuppaladadium Sowmya, Ravi Rowmika, Murthy Ch Lakshmi N, Quoseena Mir, Babu Nukala Sarath, Idris Mohammed M", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT4", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4" } ], "reference": [ { "type": "PubMed", "id": "35134499", "url": "https://glygen.org/publication/PubMed/35134499" } ] }, { "title": "Identification of environmental factors that promote intestinal inflammation.", "journal": "Nature", "date": "2022", "authors": "Sanmarco Liliana M, Chao Chun-Cheih, Wang Yu-Chao, Kenison Jessica E, Li Zhaorong, Rone Joseph M, Rejano-Gordillo Claudia M, Polonio Carolina M, Gutierrez-Vazquez Cristina, Piester Gavin, Plasencia Agustin, Li Lucinda, Giovannoni Federico, Lee Hong-Gyun, Faust Akl Camilo, Wheeler Michael A, Mascanfroni Ivan, Jaronen Merja, Alsuwailm Moneera, Hewson Patrick, Yeste Ada, Andersen Brian M, Franks Diana G, Huang Chien-Jung, Ekwudo Millicent, Tjon Emily C, Rothhammer Veit, Takenaka Maisa, de Lima Kalil Alves, Linnerbauer Mathias, Guo Lydia, Covacu Ruxandra, Queva Hugo, Fonseca-Castro Pedro Henrique, Bladi Maha Al, Cox Laura M, Hodgetts Kevin J, Hahn Mark E, Mildner Alexander, Korzenik Joshua, Hauser Russ, Snapper Scott B, Quintana Francisco J", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT4", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4" } ], "reference": [ { "type": "PubMed", "id": "36266581", "url": "https://glygen.org/publication/PubMed/36266581" } ] }, { "title": "Modulation of Zebrafish (Danio rerio) Intestinal Mucosal Barrier Function Fed Different Postbiotics and a Probiotic from Lactobacilli.", "journal": "Microorganisms", "date": "2023", "authors": "Rawling Mark, Schiavone Marion, Mugnier Am\u00e9lie, Leclercq Eric, Merrifield Daniel, Foey Andrew, Apper Emmanuelle", "evidence": [ { "database": "UniProtKB", "id": "Q5TKT4", "url": "https://www.uniprot.org/uniprotkb/Q5TKT4" } ], "reference": [ { "type": "PubMed", "id": "38138044", "url": "https://glygen.org/publication/PubMed/38138044" } ] } ], "pathway": [ { "id": "dre:553959", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553959", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q16552-1", "protein_name": "Interleukin-17A", "gene_name": "IL17A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTPGKTSLVSLLLLLSLEAIVKAGITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA", "length": 155 }, "evidence": [ { "id": "RGD:2888", "url": "https://alliancegenome.org/gene/RGD:2888#orthology", "database": "AGR" }, { "id": "HGNC:5981", "url": "https://alliancegenome.org/gene/HGNC:5981#orthology", "database": "AGR" }, { "id": "MGI:107364", "url": "https://alliancegenome.org/gene/MGI:107364#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061031-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061031-3#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5BJ95-1", "protein_name": "Interleukin-17F", "gene_name": "Il17f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKGSCETTMVKSLLLLMLGFAIISSGAARRNPKVGLSALQKAGNCPPLEDNSVRVDIRIFNQNQGISVPRDFQNRSSSPWDYNITRDPDRFPSEIAEAQCRHSGCINAQGQEDGSMNSVPIQQEILVLRREPQGCSNSFRLEKMLIKVGCTCVTPIVHHAA", "length": 161 }, "evidence": [ { "id": "HGNC:16404", "url": "https://alliancegenome.org/gene/HGNC:16404#orthology", "database": "AGR" }, { "id": "MGI:2676631", "url": "https://alliancegenome.org/gene/MGI:2676631#orthology", "database": "AGR" }, { "id": "RGD:1311398", "url": "https://alliancegenome.org/gene/RGD:1311398#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061031-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061031-3#orthology", "database": "AGR" } ], 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"database": "AGR" }, { "id": "HGNC:5981", "url": "https://alliancegenome.org/gene/HGNC:5981#orthology", "database": "AGR" }, { "id": "MGI:107364", "url": "https://alliancegenome.org/gene/MGI:107364#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061031-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061031-3#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q62386-1", "protein_name": "Interleukin-17A", "gene_name": "Il17a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPGRASSVSLMLLLLLSLAATVKAAAIIPQSSACPNTEAKDFLQNVKVNLKVFNSLGAKVSSRRPSDYLNRSTSPWTLHRNEDPDRYPSVIWEAQCRHQRCVNAEGKLDHHMNSVLIQQEILVLKREPESCPFTFRVEKMLVGVGCTCVASIVRQAA", "length": 158 }, "evidence": [ { "id": "RGD:2888", "url": "https://alliancegenome.org/gene/RGD:2888#orthology", "database": "AGR" }, { "id": "HGNC:5981", "url": "https://alliancegenome.org/gene/HGNC:5981#orthology", "database": "AGR" }, { "id": "MGI:107364", 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"uniprot_id": "Q5TYP9_DANRE", "mass": { "chemical_mass": 11381.0, "monoisotopic_mass": 11381.0 }, "refseq": { "ac": "NP_001096095", "name": "chemokine (C-C motif) ligand 38, duplicate 4 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096095" }, "gene_names": [ { "name": "ccl38a.4", "type": "recommended", "evidence": [ { "id": "Q5TYP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYP9" } ] }, { "name": "ccl38a.4", "type": "synonym", "evidence": [ { "id": "NP_001096095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096095" } ] }, { "name": "si:dkeyp-59a8.3", "type": "synonym", "evidence": [ { "id": "NP_001096095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096095" }, { "id": "Q5TYP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYP9" } ] }, { "name": "zgc:171266", "type": "synonym", "evidence": [ { "id": "NP_001096095", "database": "RefSeq", "url": 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"NP_001096095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096095" } ] }, { "name": "chemokine CCL-C20d", "type": "synonym", "evidence": [ { "id": "NP_001096095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096095" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC150345.1, AL920330.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1 and EB981374.1. On or before Aug 7, 2013 this sequence version replaced NP_001076357.2, NP_001096095.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001096095", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096095" } ] }, { "annotation": "Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).", "evidence": [ { "database": "UniProtKB", "id": "Q5TYP9", "url": "https://www.uniprot.org/uniprotkb/Q5TYP9#function" }, { "database": "UniProtKB", "id": "ARBA00044740", "url": "https://www.uniprot.org/uniprotkb/ARBA00044740#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TYP9", "url": "https://www.uniprot.org/uniprotkb/Q5TYP9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ccl38a.4", "url": "https://www.uniprot.org/uniprotkb/Q5TYP9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041014-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-163", "database": "AGR", "categories": [ 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:793030", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793030", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TTHTECH", "url": "https://omabrowser.org/oma/group/TTHTECH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5TYP9", "url": "https://www.orthodb.org/?gene=Q5TYP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12015:SF183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12015:SF183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00048", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00048", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-380108", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-380108", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-416476", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-416476", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-444473", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-444473", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001096095", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096095", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5TYP9", "url": "https://www.uniprot.org/uniprotkb/Q5TYP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TYP9-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041014-163", "url": "https://zfin.org/ZDB-GENE-041014-163", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRQSCIFIACLVLVAFCSVDGSDFSQNPDKCCFSFSTIKIPVKQVQSYHTTHFQCQKNGIIFVTEQKEICADPTERWVQRLMNLVDARLVKDTEASSNGSP", "length": 101, "header": "tr|Q5TYP9-1|Q5TYP9_DANRE Isoform 1 of C-C motif chemokine OS=Danio rerio OX=7955 GN=ccl38a.4 PE=3 SV=1 CANONICAL=Q5TYP9-1" }, "isoforms": [ { "isoform_ac": "Q5TYP9-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYP9/entry#Q5TYP9-1", "sequence": { "sequence": "MRQSCIFIACLVLVAFCSVDGSDFSQNPDKCCFSFSTIKIPVKQVQSYHTTHFQCQKNGIIFVTEQKEICADPTERWVQRLMNLVDARLVKDTEASSNGSP", "length": 101, "header": "tr|Q5TYP9-1|Q5TYP9_DANRE Isoform 1 of C-C motif chemokine OS=Danio rerio OX=7955 GN=ccl38a.4 PE=3 SV=1 CANONICAL=Q5TYP9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "CC chemokines in zebrafish: evidence for extensive intrachromosomal gene duplications.", "journal": "Genomics", "date": "2006", "authors": "Peatman Eric, Liu Zhanjiang", "evidence": [ { "database": "UniProtKB", "id": "Q5TYP9", "url": "https://www.uniprot.org/uniprotkb/Q5TYP9" } ], "reference": [ { "type": "PubMed", "id": "16697551", "url": "https://glygen.org/publication/PubMed/16697551" } ] }, { "title": "Extensive expansion and diversification of the chemokine gene family in zebrafish: identification of a novel chemokine subfamily CX.", "journal": "BMC Genomics", "date": "2008", "authors": "Nomiyama Hisayuki, Hieshima Kunio, Osada Naoki, Kato-Unoki Yoko, Otsuka-Ono Kaori, Takegawa Sumio, Izawa Toshiaki, Yoshizawa Akio, Kikuchi Yutaka, Tanase Sumio, Miura Retsu, Kusuda Jun, Nakao Miki, Yoshie Osamu", "evidence": [ { "database": "UniProtKB", "id": "Q5TYP9", "url": "https://www.uniprot.org/uniprotkb/Q5TYP9" } ], "reference": [ { "type": "PubMed", "id": "18482437", "url": "https://glygen.org/publication/PubMed/18482437" } ] }, { "title": "Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history.", "journal": "Genes Cells", "date": "2013", "authors": "Nomiyama Hisayuki, Osada Naoki, Yoshie Osamu", "evidence": [ { "database": "UniProtKB", "id": "Q5TYP9", "url": "https://www.uniprot.org/uniprotkb/Q5TYP9" } ], "reference": [ { "type": "PubMed", "id": "23145839", "url": "https://glygen.org/publication/PubMed/23145839" } ] }, { "title": "Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.", "journal": "J. Immunol.", "date": "2014", "authors": "Briolat Val\u00e9rie, Jouneau Luc, Carvalho Ralph, Palha Nuno, Langevin Christelle, Herbomel Philippe, Schwartz Olivier, Spaink Herman P, Levraud Jean-Pierre, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "Q5TYP9", "url": "https://www.uniprot.org/uniprotkb/Q5TYP9" } ], "reference": [ { "type": "PubMed", "id": "24683187", "url": "https://glygen.org/publication/PubMed/24683187" } ] }, { "title": "Gene-expression analysis of hair cell regeneration in the zebrafish lateral line.", "journal": "Proc. Natl. Acad. Sci. 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Immunol.", "date": "2014", "authors": "Briolat Val\u00e9rie, Jouneau Luc, Carvalho Ralph, Palha Nuno, Langevin Christelle, Herbomel Philippe, Schwartz Olivier, Spaink Herman P, Levraud Jean-Pierre, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ0", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ0" } ], "reference": [ { "type": "PubMed", "id": "24683187", "url": "https://glygen.org/publication/PubMed/24683187" } ] }, { "title": "Leukocyte invasion of the brain after peripheral trauma in zebrafish (Danio rerio).", "journal": "Exp. Mol. 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The reference sequence was derived from JBMGRA010000020.1. On Mar 15, 2008 this sequence version replaced NP_001025258.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001035422", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001035422" } ] }, { "annotation": "Serves as substrate adapter subunit in an E3 ubiquitin ligase complex zyg11-cul2-elongin BC. 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Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ1", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ1" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:555349", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555349", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GLF0-1", "protein_name": "Zyg-11 family member A, cell cycle regulator", "gene_name": "Zyg11a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVHFLHPLLWPRTLVLPYAQQDAQGHCLVQEEASPYPLVNICMDVLIAKLDKWCSKRPDGTLCLPEHWYFPHEIADKFLERMAWQGKLTDRTASIFQGKQVSLKLMNIRRVKLSAAAFTQAFCHHKLTEVDATSVDSQLLAPDIVHALQGSAWIQKNLQCLVLDSVSVPQNSGLLALGQFTGLHTLSLANVSFRNEDLVGVSQLPSLESLDISNTLVTDISALLSCKNRLRSLTMHYLKCLAMNNPQILDVIRQLKCLLHLDISDHRQLKSDLAFYLLQQKDILPNLISLDISGGTDITDQVVESFLQHRPAMRFVGLLYTDAGYSDFFMGRQDLKVAGGANMSQISEALSRYRHRSCFVKEALYRLFTETLSLRVILPVVLKLVAIGMRNHPLDLPVQFTASACALNLTHQGLARGMPVRLLSEITYLLFKATKNFPYYQQLQKNCLLSLTSSRILMDVPFDRFDAARLVLRWVCKRESPKMQMMAVSITSILALKLSPEEIEQFQEELALAVKELLTIIRQKMAENLNDVTLLFTLKALWNLTDECPLACKYFIENEGLATIVQVLETFSVSAIQSKVLGLLNNMAEVRELSPALVTEDLMEHTVSLLHSSDIEVSFLAAGVIAHLTCDRQQWLSHSPRRRALLQDLHLTIQNWPSSRCDMSALVTYRSFKAFPPLLVNFSQPEVQRWALWAIHHVCNKNPSKYCKLLLEEGGLQLMYDIQEHDQASAQVRQMVSSILKEFRMHFTSFRRPPQPQRPF", "length": 760 }, "evidence": [ { "id": "HGNC:32058", "url": "https://alliancegenome.org/gene/HGNC:32058#orthology", "database": "AGR" }, { "id": "RGD:1309582", "url": "https://alliancegenome.org/gene/RGD:1309582#orthology", "database": "AGR" }, { "id": "MGI:2446208", "url": "https://alliancegenome.org/gene/MGI:2446208#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-17#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2BFL2-1", "protein_name": "Protein zyg-11 homolog A", "gene_name": "Zyg11a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWQGKLTDRTASIFQGKQMSLKLINIPRVKLSAAAFTKAFCHHKLIEVNATSVDSELLAPDIIHALQSSAWIQKNLQCLVLDSVSIPPNSGLVALSHFTGLHTLSVANVSFCNEDLVSVSQLPNLGSLDISNTLVTNISALLSCKNRLRSLTMHYLKCLAMNSPQVLAVIRQLKCLLHLDISDHQQLRSDLAFYLLQQKDILPNLTSLDISGGTDVTDQAVESFLQHRPAMRFVGLLYTDAGYSDFFTAKQGLKVAGGANMSQISEALSRYRNRSCFVKEALFRLFTETLSLRAVLPVMLKLVAIGMRNHPLDLPVQFTASACALNLTRQELARGMPVRLLAEITDLLFKATKNFPYYQQLQKNCLLSLTSSRILMDVPFDRFDAAKLALRWVCRRESPKLRTMAVSITSILALKLSPEEMGQLQEELIMAIKELLTIIRQKLAENLDDVTFLFTLKALWNLTDECPLACKYFMENEGLATVIRVLETFSISVIQSKVLGLLNNVAEVRELSSKLVTEDVIERIISLLHSSNLEVSFLAAGVLAHLTCDRQHWLSRDLQRTDLLRYLHLAIQNWPSSRCDMSVLVTYRSFKAFSPLLVNFSQPEVQRWALWAIHHVCSKNPRPKDV", "length": 627 }, "evidence": [ { "id": "HGNC:32058", "url": "https://alliancegenome.org/gene/HGNC:32058#orthology", "database": "AGR" }, { "id": "RGD:1309582", "url": "https://alliancegenome.org/gene/RGD:1309582#orthology", "database": "AGR" }, { "id": "MGI:2446208", "url": "https://alliancegenome.org/gene/MGI:2446208#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-17#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M8P2-1", "protein_name": "Zyg-11 family member B, cell cycle regulator", "gene_name": "Zyg11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEDQAHTAMEEASPYSLLDICLSFLTTNLEKFCSARQDGTLCLQEPGVFPQEVADRLLQTIALHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKAFCHHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESLDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFILQRPSMQFVGLLATDAGYSEFLTGKGHLKVSGEANETQIAEALRRYSERAFFVREALFHLFSLTHVMEKTKPDILKLVVTGMRNHPMNLPVQLAASACVFNLTKQDLALGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGAELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESFPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLISRGEQAWTLSRSQRNSLLDDLHSAILKWPTPECEMVAYRSFNPFFPLLGCFTTPGVQLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKEHEQTDPYVQQIAVAILDSLEKHIVRHGRPPPCKKQPQARLN", "length": 744 }, "evidence": [ { "id": "RGD:1307814", "url": "https://alliancegenome.org/gene/RGD:1307814#orthology", "database": "AGR" }, { "id": "MGI:2685277", "url": "https://alliancegenome.org/gene/MGI:2685277#orthology", "database": "AGR" }, { "id": "HGNC:25820", "url": "https://alliancegenome.org/gene/HGNC:25820#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-17#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UFS0-1", "protein_name": "Protein zyg-11 homolog B", "gene_name": "Zyg11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPEDQAHAAMEEASPYSLLDICLSFLTTNLEKFCSARQDGTLCLQEPGVFPQEVADRLLQTIAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKAFCHHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESLDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFIQQRPSMQFVGLLATDAGYSEFLMGKGHLKVSGEANETQIAEALRRYSERAFFVREALFHLFSLTHVMEKTKPDILKLVVTGMRNHPMNLPVQLAASACVFNLTKQDLALGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGAELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESFPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLISRGEQAWTLSRSQRNSLLDDLHSAILKWPTPECEMVAYRSFNPFFPLLGCFTTPGVQLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKEHEQTDPYVQQIAVAILDSLEKHIVRHGRPPPCKKQPQARLN", "length": 744 }, "evidence": [ { "id": "RGD:1307814", "url": "https://alliancegenome.org/gene/RGD:1307814#orthology", "database": "AGR" }, { "id": "MGI:2685277", "url": "https://alliancegenome.org/gene/MGI:2685277#orthology", "database": "AGR" }, { "id": "HGNC:25820", "url": "https://alliancegenome.org/gene/HGNC:25820#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-17#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6WRX3-1", "protein_name": "Protein zyg-11 homolog A", "gene_name": "ZYG11A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVHFLHPGHTPRNIVPPDAQKDALGCCVVQEEASPYTLVNICLNVLIANLEKLCSERPDGTLCLPEHWSFPQEVAERFLRVMTWQGKLTDRTASIFRGNQMKLKLVNIQKAKISTAAFIKAFCRHKLIELNATAVHADLPVPDIISGLCSNRWIQQNLQCLLLDSTSIPQNSRLLFFSQLTGLRILSVFNVCFHTEDLANVSQLPRLESLDISNTLVTDISALLTCKDRLKSLTMHYLKCLAMTKSQILAVIRELKCLLHLDISDHRQLKSDLAFHLLQQKDILPNVVSLDISGGNCITDEAVELFIRLRPAMQFVGLLATDAGSSDFFTTKQGLRVAGGASMSQISEALSRYRNRSCFVKEALHRLFTETFSMEVTMPAILKLVAIGMRNHPLDLRVQFTASACALNLTRQGLAKGMPVRLLSEVTCLLFKALKNFPHYQQLQKNCLLSLTNSRILVDVPFDRFDAAKFVMRWLCKHENPKMQTMAVSVTSILALQLSPEQTAQLEELFMAVKELLAIVKQKTTENLDDVTFLFTLKALWNLTDGSPAACKHFIENQGLQIFIQVLETFSESAIQSKVLGLLNNIAEVRELSSKLVTEDVLKHINSLLCSREMEVSYFAAGIIAHLTSDRQLWISRDFQRRTLLQDLHATIQNWPSSSCKMTALVTYRSFKTFFPLLGNFSQPEVQLWALWAMYHVCSKNPSKYCKMLVEEEGLQLLCDIQEHSEATPKAQQIAASILDDFRMHFMNYQRPTLCQMPF", "length": 759 }, "evidence": [ { "id": "HGNC:32058", "url": "https://alliancegenome.org/gene/HGNC:32058#orthology", "database": "AGR" }, { "id": "RGD:1309582", "url": "https://alliancegenome.org/gene/RGD:1309582#orthology", "database": "AGR" }, { "id": "MGI:2446208", "url": "https://alliancegenome.org/gene/MGI:2446208#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-17#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9C0D3-1", "protein_name": "Protein zyg-11 homolog B", "gene_name": "ZYG11B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPEDQAGAAMEEASPYSLLDICLNFLTTHLEKFCSARQDGTLCLQEPGVFPQEVADRLLRTMAFHGLLNDGTVGIFRGNQMRLKRACIRKAKISAVAFRKAFCHHKLVELDATGVNADITITDIISGLGSNKWIQQNLQCLVLNSLTLSLEDPYERCFSRLSGLRALSITNVLFYNEDLAEVASLPRLESLDISNTSITDITALLACKDRLKSLTMHHLKCLKMTTTQILDVVRELKHLNHLDISDDKQFTSDIALRLLEQKDILPNLVSLDVSGRKHVTDKAVEAFIQQRPSMQFVGLLATDAGYSEFLTGEGHLKVSGEANETQIAEALKRYSERAFFVREALFHLFSLTHVMEKTKPEILKLVVTGMRNHPMNLPVQLAASACVFNLTKQDLAAGMPVRLLADVTHLLLKAMEHFPNHQQLQKNCLLSLCSDRILQDVPFNRFEAAKLVMQWLCNHEDQNMQRMAVAIISILAAKLSTEQTAQLGTELFIVRQLLQIVKQKTNQNSVDTTLKFTLSALWNLTDESPTTCRHFIENQGLELFMRVLESFPTESSIQQKVLGLLNNIAEVQELHSELMWKDFIDHISSLLHSVEVEVSYFAAGIIAHLISRGEQAWTLSRSQRNSLLDDLHSAILKWPTPECEMVAYRSFNPFFPLLGCFTTPGVQLWAVWAMQHVCSKNPSRYCSMLIEEGGLQHLYNIKDHEHTDPHVQQIAVAILDSLEKHIVRHGRPPPCKKQPQARLN", "length": 744 }, "evidence": [ { "id": "RGD:1307814", "url": "https://alliancegenome.org/gene/RGD:1307814#orthology", "database": "AGR" }, { "id": "MGI:2685277", "url": "https://alliancegenome.org/gene/MGI:2685277#orthology", "database": "AGR" }, { "id": "HGNC:25820", "url": "https://alliancegenome.org/gene/HGNC:25820#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-17#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cranial skeletal system development", "id": "GO:1904888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904888", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ1", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ1" } ], "pmid": "" }, { "name": "notochord development", "id": "GO:0030903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030903", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ1", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Cul2-RING ubiquitin ligase complex", "id": "GO:0031462", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031462", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ1", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 523, "end_pos": 525, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 523, "end_pos": 525 }, { "start_pos": 67, "end_pos": 69 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5TYQ3-1", "uniprot_ac": "Q5TYQ3", "uniprot_id": "COA7_DANRE", "mass": { "chemical_mass": 25522.0, "monoisotopic_mass": 25522.0 }, "refseq": { "ac": "NP_001025255", "name": "cytochrome c oxidase assembly factor 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025255" }, "gene_names": [ { "name": "coa7", "type": "recommended", "evidence": [ { "id": "Q5TYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3" } ] }, { "name": "coa7", "type": "synonym", "evidence": [ { "id": "NP_001025255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025255" } ] }, { "name": "selrc1", "type": "synonym", "evidence": [ { "id": "NP_001025255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025255" }, { "id": "Q5TYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3" } ] }, { "name": "si:ch211-11m18.2", "type": "synonym", "evidence": [ { "id": "NP_001025255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025255" }, { "id": "Q5TYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3" } ] }, { "name": "zgc:136252", "type": "synonym", "evidence": [ { "id": "NP_001025255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025255" }, { "id": "Q5TYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase assembly factor 7", "type": "recommended", "evidence": [ { "id": "Q5TYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3/entry#names_and_taxonomy" } ] }, { "name": "Beta-lactamase hcp-like protein", "type": "synonym", "evidence": [ { "id": "Q5TYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3/entry#names_and_taxonomy" } ] }, { "name": "Sel1 repeat containing 1", "type": "synonym", "evidence": [ { "id": "NP_001025255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025255" } ] }, { "name": "Sel1 repeat-containing protein 1", "type": "synonym", "evidence": [ { "id": "Q5TYQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3/entry#names_and_taxonomy" } ] }, { "name": "beta-lactamase hcp-like protein", "type": "synonym", "evidence": [ { "id": "NP_001025255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025255" } ] }, { "name": "cytochrome c oxidase assembly factor 7", "type": "synonym", "evidence": [ { "id": "NP_001025255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025255" } ] }, { "name": "hcp beta-lactamase-like protein C1orf163 homolog", "type": "synonym", "evidence": [ { "id": "NP_001025255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025255" } ] }, { "name": "sel1 repeat-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001025255", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025255" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01015037.1, GDQQ01003439.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505385, SAMEA3505391 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. On Aug 6, 2005 this sequence version replaced XP_682828.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025255", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025255" } ] }, { "annotation": "May be required for assembly of mitochondrial respiratory chain complexes.", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ3", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3#function" } ] } ], "disease": [ { "disease_id": "DOID:0070465", "recommended_name": { "id": "DOID:0070465", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070465", "name": "autosomal recessive spinocerebellar ataxia with axonal neuropathy 3", "description": "An autosomal recessive cerebellar ataxia characterized by onset of slowly progressive axonal peripheral neuropathy in the first decade of life, evident in distal muscle weakness and atrophy and distal sensory impairment, followed by cerebellar ataxia and atrophy that has_material_basis_in homozygous or compound heterozygous mutation in the COA7 gene on chromosome 1p32.3." }, "synonyms": [ { "id": "DOID:0070465", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070465", "name": "spinocerebellar ataxia with axonal neuropathy 3", "description": "" }, { "id": "DOID:0070465", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070465", "name": "SCAN3", "description": "" }, { "id": "DOID:0070465", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070465", "name": "spinocerebellar ataxia with axonal neuropathy type 3", "description": "" }, { "id": "MONDO:0020770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020770", "name": "spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 3", "description": "" }, { "id": "MONDO:0020770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020770", "name": "SCAN3", "description": "" }, { "id": "MIM:618387", "resource": "MIM", "url": "https://www.omim.org/entry/618387", "name": "Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 3", "description": "Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070465", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070465" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ3", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "coa7", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041014-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-16", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5TYQ3", "url": "https://alphafold.ebi.ac.uk/entry/Q5TYQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000019355", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000019355", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "555268", "url": "https://www.ncbi.nlm.nih.gov/gene/555268", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040239", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040239", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:555268", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555268", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PGCINAG", "url": "https://omabrowser.org/oma/group/PGCINAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5TYQ3", "url": "https://www.orthodb.org/?gene=Q5TYQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13891", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13891", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13891:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13891:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5TYQ3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5TYQ3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025255", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025255", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5TYQ3", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TYQ3-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041014-16", "url": "https://zfin.org/ZDB-GENE-041014-16", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAGLINFEDEQEVKQFLDNLGVEYSYQCYREKDPEGCHRLADYLEGVKKNYESTAQVLQHNCEVNAHAQSCYKLGAYHVTGKGGMKKCLKTAYSCFLKSCNTQGKKSVDACHNVGLLAQDGRALETGPDTTVARQYFEKACEGGFAPSCFNLSTLYIQGFPGLDKSMPLALKYALKACDLGHVWGCANASRMYKLGDGTDKDEQRAEELKNRAKDLHGQEKERQLKFGE", "length": 229, "header": "sp|Q5TYQ3-1|COA7_DANRE Isoform 1 of Cytochrome c oxidase assembly factor 7 OS=Danio rerio OX=7955 GN=coa7 PE=2 SV=1 CANONICAL=Q5TYQ3-1" }, "isoforms": [ { "isoform_ac": "Q5TYQ3-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3/entry#Q5TYQ3-1", "sequence": { "sequence": "MAGLINFEDEQEVKQFLDNLGVEYSYQCYREKDPEGCHRLADYLEGVKKNYESTAQVLQHNCEVNAHAQSCYKLGAYHVTGKGGMKKCLKTAYSCFLKSCNTQGKKSVDACHNVGLLAQDGRALETGPDTTVARQYFEKACEGGFAPSCFNLSTLYIQGFPGLDKSMPLALKYALKACDLGHVWGCANASRMYKLGDGTDKDEQRAEELKNRAKDLHGQEKERQLKFGE", "length": 229, "header": "sp|Q5TYQ3-1|COA7_DANRE Isoform 1 of Cytochrome c oxidase assembly factor 7 OS=Danio rerio OX=7955 GN=coa7 PE=2 SV=1 CANONICAL=Q5TYQ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ3", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:555268", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555268", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PGZ5-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "COA7", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGLIDFGDEEEVRSYLENLHVEYSYQCFKEKDPEGCQRLADYLDAVKKDFEAAARVLRDNCELHGHSESCYRLGAYQAIGKGGLAADLKAAYKSFLKSCEKGGKKSVNACHSVGLLAHDGRVNDDKPDPVVARDYYTKACDGNFAPSCFNLSVIYLQGAAGVPKDMNRALKYSLKGCELGHIWACANASRMYKLGDGVEKNDDKAEDLKNRAKQLHKEQKEASSSLTFGE", "length": 231 }, "evidence": [ { "id": "Q5TYQ3", "url": "https://omabrowser.org/oma/group/Q5TYQ3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9TD90-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "COA7", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGLVDFQDEEQVKSFLENMEVECNYQCYREKDPDGCYRLVDYLEGIQKNFDEAAKVLKFNCEENKHSDSCYKLGAYYVTGKGGLSQDLKAASNCFLMACEKPGKKSTEACHNVGLLAHDGQVNEDGQPNLERARDYYTRACDGNYAASCFNLSAMFLQGAPSFPKDMGLACKYAMKACDLGHVWACANASRMYKLGDGVDKDEAKAEELKNRARQLHKEQQKSVQPLTFG", "length": 231 }, "evidence": [ { "id": "Q5TYQ3", "url": "https://omabrowser.org/oma/group/Q5TYQ3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4AC65-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "Coa7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGLVDFQDEEQVKSFLENMEVECHYQCYREKDPEGCYRLVDYLEGIQKNFDEAAKVLKFNCEKYGHGDSCYKLGGYYVTGKGGLTQDLKAAFSCFLMACEKPGKKSVESCHNVGLLAHDGQVNEDGQPDLGKARDYYTRACDGSYAASCFNLSAMFLQGAPGFPKDMGLACKYSMKACDLGHVWACANASRMYKLGDGVDKDEAKAEMLKNRAQQLHKEQQKNVQPLTFG", "length": 231 }, "evidence": [ { "id": "RGD:1305274", "url": "https://alliancegenome.org/gene/RGD:1305274#orthology", "database": "AGR" }, { "id": "MGI:1917143", "url": "https://alliancegenome.org/gene/MGI:1917143#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-16#orthology", "database": "AGR" }, { "id": "HGNC:25716", "url": "https://alliancegenome.org/gene/HGNC:25716#orthology", "database": "AGR" }, { "id": "FB:FBgn0039965", "url": "https://alliancegenome.org/gene/FB:FBgn0039965#orthology", "database": "AGR" }, { "id": "Q5TYQ3", "url": "https://omabrowser.org/oma/group/Q5TYQ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GW05-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "LOC100756398", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGLVDFQDEEQVKSFLENMKVECHYQCYREKDPDGCYRLVDYLEGIQKNFDEAAKVLKFNCEDNGHSDSCYKLGAYYVTGKGGLTQDLKAASACFLMACEKPGKKSVESCHNVGLLAHDGQINEDGQPDLRKARDYYTRACDGNYAASCFNLSTMFLQGAPGFPKDMGLACKYSMKACDLGHVWACANASRMYKLGDGVDKDEAKAEMLKNRAQQLHKEQQKNVQPVTFG", "length": 231 }, "evidence": [ { "id": "Q5TYQ3", "url": "https://omabrowser.org/oma/group/Q5TYQ3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LRZ7-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "COA7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGLVDFQDEEQVKSFLENMEVECNYQCYQEKDPDGCYRLVDYLEGIQKNFNEAAKVLKFNCEENKHSDSCYKLGAYYVTGKGGLTQDLKAASSCFLMACEKPGKKSVEACHNVGLLAHDGQVNEDGQPDLPRARDYYTRACDGNYASSCFNLSTMFLQGPGFPKDMGLACKYSMKACDLGHVWACANASRMYRLGDGVDKDEAKAEELKNRARQLHKEQQKSVQPLTFG", "length": 230 }, "evidence": [ { "id": "Q5TYQ3", "url": "https://omabrowser.org/oma/group/Q5TYQ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q921H9-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "Coa7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGLVDFQDEEQVKSFLENMEVECHYQCYREKDPEGCYRLVDYLEGIQKNFDEAAKVLKFNCEKYGHGDSCYKLGAYYVTGKGGLTQDLKAASSCFLMACEKPGKKSVESCHNVGLLAHDGQVNEDGQPDLGKARDYYSRACDGGYAASCFNLSAMFLQGAPGFPKDMGLACKYSMKACDLGHVWACANASRMYKLGDGVDKDEAKAEVLKNRARQLHKEQQKNVQPLTFG", "length": 231 }, "evidence": [ { "id": "RGD:1305274", "url": "https://alliancegenome.org/gene/RGD:1305274#orthology", "database": "AGR" }, { "id": "MGI:1917143", "url": "https://alliancegenome.org/gene/MGI:1917143#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-16#orthology", "database": "AGR" }, { "id": "HGNC:25716", "url": "https://alliancegenome.org/gene/HGNC:25716#orthology", "database": "AGR" }, { "id": "FB:FBgn0039965", "url": "https://alliancegenome.org/gene/FB:FBgn0039965#orthology", "database": "AGR" }, { "id": "Q5TYQ3", "url": "https://omabrowser.org/oma/group/Q5TYQ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96BR5-1", "protein_name": "Cytochrome c oxidase assembly factor 7", "gene_name": "COA7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGMVDFQDEEQVKSFLENMEVECNYHCYHEKDPDGCYRLVDYLEGIRKNFDEAAKVLKFNCEENQHSDSCYKLGAYYVTGKGGLTQDLKAAARCFLMACEKPGKKSIAACHNVGLLAHDGQVNEDGQPDLGKARDYYTRACDGGYTSSCFNLSAMFLQGAPGFPKDMDLACKYSMKACDLGHIWACANASRMYKLGDGVDKDEAKAEVLKNRAQQLHKEQQKGVQPLTFG", "length": 231 }, "evidence": [ { "id": "RGD:1305274", "url": "https://alliancegenome.org/gene/RGD:1305274#orthology", "database": "AGR" }, { "id": "MGI:1917143", "url": "https://alliancegenome.org/gene/MGI:1917143#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-16#orthology", "database": "AGR" }, { "id": "HGNC:25716", "url": "https://alliancegenome.org/gene/HGNC:25716#orthology", "database": "AGR" }, { "id": "FB:FBgn0039965", "url": "https://alliancegenome.org/gene/FB:FBgn0039965#orthology", "database": "AGR" }, { "id": "Q5TYQ3", "url": "https://omabrowser.org/oma/group/Q5TYQ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W5N0-1", "protein_name": "Cytochrome c oxidase assembly factor 7 homolog", "gene_name": "Coa7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAYDLKKESDVKEYVEKLGVEYRFGCYSEKKPEACHLLGDYLEGIKKDFEKASKVYKSTCDDYGYAKSCYKYGNYSFLGKGKSGSKGNPQVAYEYYEKGCNLNDSDACLHSGLLLVSKSMPREIDWNVPKGLEFLTKSCDLNNATACFYLSGMHISGVQKKADQSAVTASSGSGTSSPPAGQPPLKDSDYIVLKDMKKAFQFAHKACELRNMYACANLSQMYARGDGIEKNEKEAEKYKKLALEMQDEVKKQHDTLGFQQGVGMPN", "length": 266 }, "evidence": [ { "id": "RGD:1305274", "url": "https://alliancegenome.org/gene/RGD:1305274#orthology", "database": "AGR" }, { "id": "MGI:1917143", "url": "https://alliancegenome.org/gene/MGI:1917143#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-16#orthology", "database": "AGR" }, { "id": "HGNC:25716", "url": "https://alliancegenome.org/gene/HGNC:25716#orthology", "database": "AGR" }, { "id": "FB:FBgn0039965", "url": "https://alliancegenome.org/gene/FB:FBgn0039965#orthology", "database": "AGR" }, { "id": "Q5TYQ3", "url": "https://omabrowser.org/oma/group/Q5TYQ3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ3", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-disulfide reductase activity", "id": "GO:0015035", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015035", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ3", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "respiratory chain complex IV assembly", "id": "GO:0008535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008535", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ3", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 188, "end_pos": 190 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5TYQ8-1", "uniprot_ac": "Q5TYQ8", "uniprot_id": "ZC3HE_DANRE", "mass": { "chemical_mass": 74585.0, "monoisotopic_mass": 74585.0 }, "refseq": { "ac": "NP_001020695", "name": "zinc finger CCCH domain-containing protein 14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020695" }, "gene_names": [ { "name": "zc3h14", "type": "recommended", "evidence": [ { "id": "Q5TYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ] }, { "name": "si:dkey-199i12.4", "type": "synonym", "evidence": [ { "id": "NP_001020695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020695" }, { "id": "Q5TYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ] }, { "name": "zc3h14", "type": "synonym", "evidence": [ { "id": "NP_001020695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020695" } ] }, { "name": "zgc:136266", "type": "synonym", "evidence": [ { "id": "NP_001020695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020695" }, { "id": "Q5TYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH domain-containing protein 14", "type": "recommended", "evidence": [ { "id": "Q5TYQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCCH domain-containing protein 14", "type": "synonym", "evidence": [ { "id": "NP_001020695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020695" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC116476.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC116476.1. On Mar 23, 2008 this sequence version replaced NP_001020695.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001020695", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020695" } ] }, { "annotation": "RNA-binding protein involved in the biogenesis of circular RNAs (circRNAs), which are produced by back-splicing circularization of pre-mRNAs. Acts by binding to both exon-intron boundary and 3'-UTR of pre-mRNAs to promote circRNA biogenesis through dimerization and the association with the spliceosome. Also binds the poly(A) tail of mRNAs; controlling poly(A) length.", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ8", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8#function" }, { "database": "UniProtKB", "id": "Q6PJT7", "url": "https://www.uniprot.org/uniprotkb/Q6PJT7#function" }, { "database": "UniProtKB", "id": "A0AC58I416", "url": "https://www.uniprot.org/uniprotkb/A0AC58I416#function" }, { "database": "UniProtKB", "id": "RU369058", "url": "https://www.uniprot.org/uniprotkb/RU369058#function" }, { "database": "UniProtKB", "id": "A0AC58I415", "url": "https://www.uniprot.org/uniprotkb/A0AC58I415#function" }, { "database": "UniProtKB", "id": "A0AC58I418", "url": "https://www.uniprot.org/uniprotkb/A0AC58I418#function" } ] } ], "disease": [ { "disease_id": "DOID:0060308", "recommended_name": { "id": "DOID:0060308", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060308", "name": "autosomal recessive intellectual developmental disorder", "description": "A intellectual disability characterized by an autosomal recessive inheritance pattern." }, "synonyms": [ { "id": "DOID:0060308", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060308", "name": "autosomal recessive non-syndromic mental retardation", "description": "" }, { "id": "DOID:0060308", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060308", "name": "autosomal recessive mental retardation", "description": "" }, { "id": "MONDO:0009580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009580", "name": "intellectual disability, autosomal recessive 1", "description": "Any autosomal recessive non-syndromic intellectual disability in which the cause of the disease is a mutation in the PRSS12 gene." }, { "id": "MONDO:0009580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009580", "name": "PRSS12 autosomal recessive non-syndromic intellectual disability", "description": "" }, { "id": "MONDO:0009580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009580", "name": "autosomal recessive non-syndromic intellectual disability caused by mutation in PRSS12", "description": "" }, { "id": "MONDO:0009580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009580", "name": "intellectual disability, autosomal recessive 1", "description": "" }, { "id": "MONDO:0009580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009580", "name": "intellectual disability, autosomal recessive type 1", "description": "" }, { "id": "MONDO:0009580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009580", "name": "mental retardation, autosomal recessive type 1", "description": "" }, { "id": "MONDO:0009580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009580", "name": "MRT1", "description": "" }, { "id": "MONDO:0009580", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009580", "name": "mental retardation, autosomal recessive 1", "description": "" }, { "id": "MIM:249500", "resource": "MIM", "url": "https://www.omim.org/entry/249500", "name": "Intellectual developmental disorder, autosomal recessive 1", "description": "Intellectual developmental disorder, autosomal recessive 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060308", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060308" } ] }, { "disease_id": "DOID:0081217", "recommended_name": { "id": "DOID:0081217", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0081217", "name": "autosomal recessive intellectual developmental disorder 56", "description": "An autosomal recessive intellectual developmental disorder that has_material_basis_in homozygous mutation in the ZC3H14 gene on chromosome 14q31." }, "synonyms": [ { "id": "MONDO:0014930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014930", "name": "intellectual disability, autosomal recessive 56", "description": "Any autosomal recessive non-syndromic intellectual disability in which the cause of the disease is a mutation in the ZC3H14 gene." }, { "id": "MONDO:0014930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014930", "name": "MRT56", "description": "" }, { "id": "MONDO:0014930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014930", "name": "ZC3H14 autosomal recessive non-syndromic intellectual disability", "description": "" }, { "id": "MONDO:0014930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014930", "name": "autosomal recessive non-syndromic intellectual disability caused by mutation in ZC3H14", "description": "" }, { "id": "MONDO:0014930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014930", "name": "intellectual developmental disorder, autosomal recessive 56", "description": "" }, { "id": "MONDO:0014930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014930", "name": "intellectual disability, autosomal recessive 56", "description": "" }, { "id": "MONDO:0014930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014930", "name": "intellectual disability, autosomal recessive type 56", "description": "" }, { "id": "MONDO:0014930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014930", "name": "mental retardation, autosomal recessive 56", "description": "" }, { "id": "MONDO:0014930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014930", "name": "mental retardation, autosomal recessive type 56", "description": "" }, { "id": "MIM:617125", "resource": "MIM", "url": "https://www.omim.org/entry/617125", "name": "Intellectual developmental disorder, autosomal recessive 56", "description": "Intellectual developmental disorder, autosomal recessive 56" } ], "unlinked_id_list": [], "evidence": [ { "id": "0081217", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081217" } ] }, { "disease_id": "DOID:1059", "recommended_name": { "id": "DOID:1059", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1059", "name": "intellectual disability", "description": "A specific developmental disorder that involves significant limitations both in mental functioning and in adaptive behavior such as communicating, taking care of him or herself, and social skills." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "1059", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1059" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ8", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zc3h14", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041014-257", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-257", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5TYQ8", "url": "https://alphafold.ebi.ac.uk/entry/Q5TYQ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000041402", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000041402", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "562846", "url": "https://www.ncbi.nlm.nih.gov/gene/562846", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562846", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562846", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPYTHVS", "url": "https://omabrowser.org/oma/group/CPYTHVS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5TYQ8", "url": "https://www.orthodb.org/?gene=Q5TYQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14738:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14738:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5TYQ8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5TYQ8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001020695", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001020695", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58I415", "url": "https://www.uniprot.org/uniprotkb/A0AC58I415", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I415-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I415-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I416", "url": "https://www.uniprot.org/uniprotkb/A0AC58I416", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I416-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I416-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I418", "url": "https://www.uniprot.org/uniprotkb/A0AC58I418", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I418-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I418-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TYQ8", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TYQ8-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041014-257", "url": "https://zfin.org/ZDB-GENE-041014-257", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEIGTEISKKIRTAIKGKLQEFGAYVDEELPDYIMVMVANKKNPQQMADDLSLFLGNNTIKFTVWLHGVLEKLRSVAVEPPSLGPSVVHSETSIPAENSRRGAEPRALAVSSSRSDKAEGRVSSSAHENRASKRGSSERPSRLTSAVKPLMEASAEAVIDIKPDLDDDLISYDPVEHSLTSGHSQALYSRSTAERQRPAVESSRRTADTYRSSDISRGQDRSERGYRSSAESSRDLSRKRKAPVASSVVRVHRGHERGLEIEDLEEEEEDEDYGLASKVSLPSKPERKPTLPPAKQANKNLILKAISEAQESINKTTSQYTVPQRQTVPVAPRTRSASDEMSNAAIRLVQEHLHALTPQDTLHNTQSRGLASRLQLEVPEEDSREPHEYELQVLEAARLKALDTRSFIMRQPEVEQPPPIRSRLSAVNQNENAPTTSRMVQARERAEAVGGSSPKFIVTLDGVPSPLANRTDQEMETEDELNTTADLPENNNNNNTTTTTSKPAVHLRLGADLRNACDDEVEEMDIEAVQAKRQKLPERCKFWPTCKSGDECLYHHPNTQCKVFPNCKFADKCLFIHPNCKFDAKCTKADCPFTHVSRRLNSNPTRAAPALTSTVCRFFPECKKVDCPFYHPKPCRFATQCKRADCTFYHPAVAVPPRSALKWTKTQSS", "length": 669, "header": "sp|Q5TYQ8-1|ZC3HE_DANRE Isoform 1 of Zinc finger CCCH domain-containing protein 14 OS=Danio rerio OX=7955 GN=zc3h14 PE=2 SV=1 CANONICAL=Q5TYQ8-1" }, "isoforms": [ { "isoform_ac": "A0AC58I415-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8/entry#A0AC58I415-1", "sequence": { "sequence": "MVMVANKKNPQQMADDLSLFLGNNTIKFTVWLHGVLEKLRSVAVEPPSLGPSVVHSETSIPAENSRRGAEPRALAVSSSRSDKAEGRVSSSAHENRASKRGSSERPSRLTSAVKPLMEASAEAVIDIKPDLDDDLISYDPVEHSLTSGHSQALYSRSTAERQRPAVESSRRTADTYRSSDISRGQDRSERGYRSSAESSRDLSRKRKAPVASSVVRVHRGHERGLEIEDLEEEEEDEDYGLASKVSLPSKPERKPTLPPAKQANKNLILKAISEAQESINKTTSQYTVPQRQTVPVAPRTRSASDEMSNAAIRLVQEHLHALTPQDTLHNTQSRGLASRLQLEVPEEDSREPHEYELQVLEAARLKALDTRSFIMRQPEVEQPPPIRSRLSAVNQNENAPTTSRMVQARERAEAVGGSSPKFIVTLDGVPSPLANRTDQEMETEDELNTTADLPENNNNNNTTTTTSKPAVHLRLGADLRNACDDEVEEMDIEAVQAKRQKLPERCKFWPTCKSGDECLYHHPNTQCKVFPNCKFADKCLFIHPNCKFDAKCTKADCPFTHVSRRLNSNPTRAAPALTSTVCRFFPECKKVDCPFYHPKPCRFATQCKRADCTFYHPAVAVPPRSALKWTKTQSS", "length": 635, "header": "tr|A0AC58I415-1|A0AC58I415_DANRE Computationally mapped isoform of Zinc finger CCCH domain-containing protein 14 OS=Danio rerio OX=7955 GN=zc3h14 PE=1 SV=1 CANONICAL=Q5TYQ8-1" }, "locus": {} }, { "isoform_ac": "A0AC58I416-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8/entry#A0AC58I416-1", "sequence": { "sequence": "MTAIKGKLQEFGAYVDEELPDYIMVMVANKKNPQQMADDLSLFLGNNTIKFTVWLHGVLEKLRSVAVEPPSLGPSVVHSETSIPAENSRRGAEPRALAVSSSRSDKAEGRVSSSAHENRASKRGSSERPSRLTSAVKPLMEASAEAVIDIKPDLDDDLISYDPVEHSLTSGHSQALYSRSTAERQRPAVESSRRTADTYRSSDISRGQDRSERGYRSSAESSRDLSRKRKAPVASSVVRVHRGHERGLEIEDLEEEEEDEDYGLASKVSLPSKPERKPTLPPAKQANKNLILKAISEAQESINKTTSQYTVPQRQTVPVAPRTRSASDEMSNAAIRLVQEHLHALTPQDTLHNTQSRGLASRLQLEVPEEDSREPHEYELQVLEAARLKALDTRSFIMRQPEVEQPPPIRSRLSAVNQNENAPTTSRMVQARERAEAVGGSSPKFIVTLDGVPSPLANRTDQEMETEDELNTTADLPENNNNNNTTTTTSKPAVHLRLGADLRNACDDEVEEMDIEAVQAKRQKLPERCKFWPTCKSGDECLYHHPNTQCKVFPNCKFADKCLFIHPNCKFDAKCTKADCPFTHVSRRLNSNPTRAAPALTSTVCRFFPECKKVDCPFYHPKPCRFATQCKRADCTFYHPAVAVPPRSALKWTKTQSS", "length": 658, "header": "tr|A0AC58I416-1|A0AC58I416_DANRE Computationally mapped isoform of Zinc finger CCCH domain-containing protein 14 OS=Danio rerio OX=7955 GN=zc3h14 PE=1 SV=1 CANONICAL=Q5TYQ8-1" }, "locus": {} }, { "isoform_ac": "A0AC58I418-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8/entry#A0AC58I418-1", "sequence": { "sequence": "MFRYMLFVTAIKGKLQEFGAYVDEELPDYIMVMVANKKNPQQMADDLSLFLGNNTIKFTVWLHGVLEKLRSVAVEPPSLGPSVVHSETSIPAENSRRGAEPRALAVSSSRSDKAEGRVSSSAHENRASKRGSSERPSRLTSAVKPLMEASAEAVIDIKPDLDDDLISYDPVEHSLTSGHSQALYSRSTAERQRPAVESSRRTADTYRSSDISRGQDRSERGYRSSAESSRDLSRKRKAPVASSVVRVHRGHERGLEIEDLEEEEEDEDYGLASKVSLPSKPERKPTLPPAKQANKNLILKAISEAQESINKTTSQYTVPQRQTVPVAPRTRSASDEMSNAAIRLVQEHLHALTPQDTLHNTQSRGLASRLQLEVPEEDSREPHEYELQVLEAARLKALDTRSFIMRQPEVEQPPPIRSRLSAVNQNENAPTTSRMVQARERAEAVGGSSPKFIVTLDGVPSPLANRTDQEMETEDELNTTADLPENNNNNNTTTTTSKPAVHLRLGADLRNACDDEVEEMDIEAVQAKRQKLPERCKFWPTCKSGDECLYHHPNTQCKVFPNCKFADKCLFIHPNCKFDAKCTKADCPFTHVSRRLNSNPTRAAPALTSTVCRFFPECKKVDCPFYHPKPCRFATQCKRADCTFYHPAVAVPPRSALKWTKTQSS", "length": 665, "header": "tr|A0AC58I418-1|A0AC58I418_DANRE Computationally mapped isoform of Zinc finger CCCH domain-containing protein 14 OS=Danio rerio OX=7955 GN=zc3h14 PE=1 SV=1 CANONICAL=Q5TYQ8-1" }, "locus": {} }, { "isoform_ac": "Q5TYQ8-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8/entry#Q5TYQ8-1", "sequence": { "sequence": "MEIGTEISKKIRTAIKGKLQEFGAYVDEELPDYIMVMVANKKNPQQMADDLSLFLGNNTIKFTVWLHGVLEKLRSVAVEPPSLGPSVVHSETSIPAENSRRGAEPRALAVSSSRSDKAEGRVSSSAHENRASKRGSSERPSRLTSAVKPLMEASAEAVIDIKPDLDDDLISYDPVEHSLTSGHSQALYSRSTAERQRPAVESSRRTADTYRSSDISRGQDRSERGYRSSAESSRDLSRKRKAPVASSVVRVHRGHERGLEIEDLEEEEEDEDYGLASKVSLPSKPERKPTLPPAKQANKNLILKAISEAQESINKTTSQYTVPQRQTVPVAPRTRSASDEMSNAAIRLVQEHLHALTPQDTLHNTQSRGLASRLQLEVPEEDSREPHEYELQVLEAARLKALDTRSFIMRQPEVEQPPPIRSRLSAVNQNENAPTTSRMVQARERAEAVGGSSPKFIVTLDGVPSPLANRTDQEMETEDELNTTADLPENNNNNNTTTTTSKPAVHLRLGADLRNACDDEVEEMDIEAVQAKRQKLPERCKFWPTCKSGDECLYHHPNTQCKVFPNCKFADKCLFIHPNCKFDAKCTKADCPFTHVSRRLNSNPTRAAPALTSTVCRFFPECKKVDCPFYHPKPCRFATQCKRADCTFYHPAVAVPPRSALKWTKTQSS", "length": 669, "header": "sp|Q5TYQ8-1|ZC3HE_DANRE Isoform 1 of Zinc finger CCCH domain-containing protein 14 OS=Danio rerio OX=7955 GN=zc3h14 PE=2 SV=1 CANONICAL=Q5TYQ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ8", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:562846", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562846", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z443-1", "protein_name": "Zinc finger CCCH domain-containing protein 14", "gene_name": "ZC3H14", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MNDLLKPSGTFVFAPWERKGAIKGKLQELGAYVDEELPDYIMVMVANKKSQEQMTEDLSLFLGNNTVRFTVWLHGVLDKLRSVTTEPSGTKSSEPNIFESNHSSSKSSSCVSDERRREDTLPPLAVSSTRSERTDSRVSTSSQEQRNTASRQSCEDGSASRLMSTVKPLRELSPSEAVIDIKPEPDDLIDEDLNFVQENPLSRKKPIVTVTYGSSRPTAEIYRPPASRSADGSLQVHRLPQQGNLQGNRQLDTQSCRSLETVQLCNPEAFGSLAESYRPTSKLSADKVGSEEEGSRKRRLPIVSSVVKVKKFCNDGEEEEEEEDYGLRTGSISSSVSVPAKPERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSAVPQKQTVPVAPRTRISPEESHLEVIHLQSRLPALCSQLQVEEPKEQAVEGIQGAEQKELSSRLQVDPVIEDTLQVTQDYYDGESMVHTDTRSFILKKPKLSEEIAAQNQQLGKRATEAMRVLSGRLIQTRDQIAQPEKPASPKFIVTLDGVPSPPGYLSDQEEEDMYITEGLKPIPQNICAGKGLKGLRAQQMQIVTRQLDSSDVEMEQLNVLQKQEKVLERCKYWPACKNGDECVYHHPTQPCKVFPNCKFADKCLFIHPNCKYDAKCTKPDCPYTHASRRNPLPSPKPVPLPTQSVSSSSPLCKFFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTIAVPPRHALKWTRTQTSE", "length": 737 }, "evidence": [ { "id": "Q5TYQ8", "url": "https://omabrowser.org/oma/group/Q5TYQ8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P32505-1", "protein_name": "Nuclear polyadenylated RNA-binding protein NAB2", "gene_name": "NAB2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSQEQYTENLKVIVAEKLAGIPNFNEDIKYVAEYIVLLIVNGGTVESVVDELASLFDSVSRDTLANVVQTAFFALEALQQGESAENIVSKIRMMNAQSLGQSDIAQQQQQQQQQQQPDIAQQQPQQQPQQQPQQQPQQQPQQQPQQQPQQQPQQQPQLQPLQPQLGTQNAMQTDAPATPSPISAFSGVVNAAAPPQFAPVDNSQRFTQRGGGAVGKNRRGGRGGNRGGRNNNSTRFNPLAKALGMAGESNMNFTPTKKEGRCRLFPHCPLGRSCPHAHPTKVCNEYPNCPKPPGTCEFLHPNEDEELMKEMERTREEFQKRKADLLAAKRKPVQTGIVLCKFGALCSNPSCPFGHPTPANEDAKVIDLMWCDKNLTCDNPECRKAHSSLSKIKEVKPISQKKAAPPPVEKSLEQCKFGTHCTNKRCKYRHARSHIMCREGANCTRIDCLFGHPINEDCRFGVNCKNIYCLFRHPPGRVLPEKKGAAPNSNVPTNERPFALPENAIIENAPPQTSFTHQEQDTEMN", "length": 525 }, "evidence": [ { "id": "RGD:621850", "url": "https://alliancegenome.org/gene/RGD:621850#orthology", "database": "AGR" }, { "id": "MGI:1919824", "url": "https://alliancegenome.org/gene/MGI:1919824#orthology", "database": "AGR" }, { "id": "HGNC:20509", "url": "https://alliancegenome.org/gene/HGNC:20509#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-257", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-257#orthology", "database": "AGR" }, { "id": "FB:FBgn0028471", "url": "https://alliancegenome.org/gene/FB:FBgn0028471#orthology", "database": "AGR" }, { "id": "SGD:S000003090", "url": "https://alliancegenome.org/gene/SGD:S000003090#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3ZC82-1", "protein_name": "Zinc finger CCCH domain-containing protein 14", "gene_name": "ZC3H14", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEIGTEISRKIRSAIKGKLQELGAYVDEELPDYIMVMVANKKSQDQMTEDLSLFLGNNTIRFTVWLHGVLDKLRSVTTDPASLKSSDTNLFDGNVPSNKSSFSRGDERRHEAAVPPLAVSSTRPEKRESRVSTSSQEQKATNVRQTYDDGAATRLMSTVKPLRELAPSEDVIDIKPEPDDLIDEDLNFVQENPLSQKKTTVTLTYGSSRPSIEIYRPPATRNTDSGAHLNRLQFQQQQNSIHAAKQLDIQSSRVYETGRLCEPEVLNSLEETYSPFFRSNAEKMSIEEENFRKRKLPVVSSVVKVKKFSHDGEEEEEDDDCGSRTGSISSSVSVPAKPERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSTVSQKQTLPVAPRTRTSQEDLLAEVAQGHGRVPRISSPVKEEEAQGGSVDERQGTQQRQLLSRLQIDPVMAETLQISQDYYDMESMVHADTRSFILKKPKLCEELVVAASQASGMETADALQARSGHLVQTRDLVQPDKPASPKFIVTLDGVPSPPGYMSDQEEDMCSEGMRPAQHPAASHGGLAGLLHPQRSRVLSRQLEDPDGSFANAEMSELSVAQKPEKLLERCKYWPACKNGDECAYHHPVSPCKAFPNCKFAEKCLFVHPNCKYDAKCTKPDCPFTHMSRRTPGLPPKPVTAPAPPSSSQLCRYFPACKKMECPFYHPKHCRFNTQCTRPDCAFYHPTITVPPRHALKWIRPQTSD", "length": 735 }, "evidence": [ { "id": "Q5TYQ8", "url": "https://omabrowser.org/oma/group/Q5TYQ8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6PJT7-1", "protein_name": "Zinc finger CCCH domain-containing protein 14", "gene_name": "ZC3H14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEIGTEISRKIRSAIKGKLQELGAYVDEELPDYIMVMVANKKSQDQMTEDLSLFLGNNTIRFTVWLHGVLDKLRSVTTEPSSLKSSDTNIFDSNVPSNKSNFSRGDERRHEAAVPPLAIPSARPEKRDSRVSTSSQESKTTNVRQTYDDGAATRLMSTVKPLREPAPSEDVIDIKPEPDDLIDEDLNFVQENPLSQKKPTVTLTYGSSRPSIEIYRPPASRNADSGVHLNRLQFQQQQNSIHAAKQLDMQSSWVYETGRLCEPEVLNSLEETYSPFFRNNSEKMSMEDENFRKRKLPVVSSVVKVKKFNHDGEEEEEDDDYGSRTGSISSSVSVPAKPERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSTVPQKQTLPVAPRTRTSQEELLAEVVQGQSRTPRISPPIKEEETKGDSVEKNQGTQQRQLLSRLQIDPVMAETLQMSQDYYDMESMVHADTRSFILKKPKLSEEVVVAPNQESGMKTADSLRVLSGHLMQTRDLVQPDKPASPKFIVTLDGVPSPPGYMSDQEEDMCFEGMKPVNQTAASNKGLRGLLHPQQLHLLSRQLEDPNGSFSNAEMSELSVAQKPEKLLERCKYWPACKNGDECAYHHPISPCKAFPNCKFAEKCLFVHPNCKYDAKCTKPDCPFTHVSRRIPVLSPKPAVAPPAPPSSSQLCRYFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTINVPPRHALKWIRPQTSE", "length": 736 }, "evidence": [ { "id": "RGD:621850", "url": "https://alliancegenome.org/gene/RGD:621850#orthology", "database": "AGR" }, { "id": "MGI:1919824", "url": "https://alliancegenome.org/gene/MGI:1919824#orthology", "database": "AGR" }, { "id": "HGNC:20509", "url": "https://alliancegenome.org/gene/HGNC:20509#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-257", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-257#orthology", "database": "AGR" }, { "id": "FB:FBgn0028471", "url": "https://alliancegenome.org/gene/FB:FBgn0028471#orthology", "database": "AGR" }, { "id": "SGD:S000003090", "url": "https://alliancegenome.org/gene/SGD:S000003090#orthology", "database": "AGR" }, { "id": "Q5TYQ8", "url": "https://omabrowser.org/oma/group/Q5TYQ8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMD5-1", "protein_name": "Zinc finger CCCH domain-containing protein 14", "gene_name": "Zc3h14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEIGTEISRKIRSAIKGKLQELGAYVDEELPDYIMVMVANKKSQDQMTEDLSLFLGNNTIRFTVWLHGVLDKLRSVTTEPSSLKSPDTSIFDSNVPSNKSSFSRGDERRHEAAIPPLAVSSSRPEKRDSRVSTSSQEHKSTNVRHSYDDGASTRLMSTVKPLREPAPSEDVIDIKPEPDDLIDEDLNFVQENSLSQKKPTVTLTYGSSRPSIEIYRPPASRNADTGTHLNRPQLQQQQSSTHTAKQLDGQSSQVYEAGRLCEPEVLGSVEDTYSPFFRNNLDKMNIEEENFRKRKLPVVSSVVKVKRFSHDGEEEEEDEDYGTRVGSLSSSVSVPAKPERRPSLPPSKQANKNLILKAISEAQESVTKTTNYPAVPQKQTLPVAPRTRTSQEEVLAEMVQGQNRAPRISPPVKEEEAKGDNAEKIEGTQQRQLLSRLQIDPVTVDTMELSQDYYDMESMVHADTRSFILKKPKLSEEIVVTPNQDSGMKTADALRVLSGHLMQTRDLVQPDKPASPKFIVTLDGVPSPPGYMSDQEEEMCFEGMKPVNQTSASNKGLRGLLHPQQLHLLSRQLEDPDGSFSNAEMTDLSVAQKPEKLLERCKYWPACKNGDECVYHHPISPCKAFPNCKFAEKCLFVHPNCKYDAKCTKADCPFTHMSRRGPVLTPKPAVSSPAPSSNGQFCRYFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTITVPPRHALKWIRPQTSE", "length": 736 }, "evidence": [ { "id": "RGD:621850", "url": "https://alliancegenome.org/gene/RGD:621850#orthology", "database": "AGR" }, { "id": "MGI:1919824", "url": "https://alliancegenome.org/gene/MGI:1919824#orthology", "database": "AGR" }, { "id": "HGNC:20509", "url": "https://alliancegenome.org/gene/HGNC:20509#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-257", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-257#orthology", "database": "AGR" }, { "id": "FB:FBgn0028471", "url": "https://alliancegenome.org/gene/FB:FBgn0028471#orthology", "database": "AGR" }, { "id": "SGD:S000003090", "url": "https://alliancegenome.org/gene/SGD:S000003090#orthology", "database": "AGR" }, { "id": "Q5TYQ8", "url": "https://omabrowser.org/oma/group/Q5TYQ8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BJ05-1", "protein_name": "Zinc finger CCCH domain-containing protein 14", "gene_name": "Zc3h14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIGTEISRKIRSAIKGKLQELGAYVDEELPDYIMVMVANKKSQDQMTEDLSLFLGNNTIRFTVWLHGVLDKLRSVTTEPSSLKSPDASIFDSHVPSNKSSFSRGDERRHEAAVPPLAVSSSRPEKRDSRVSTSSQEQKSTNVRHSYDDGASTRLMSTVKPLREPAPSEDVIDIKPEPDDLIDEDLNFVQENPLSQKKPTVTLTYGSSRPSIEIYRPPASRNADTGTHLNRLQLHPQQSSAHAAKQLDVQSSQVSEAGRLCEPPVLSSVEDTYSPFFRNNLDKMSIEDENFRKRKLPVVSSVVKVKRFSHDGEEEEEDEDYGTRIGSLSSSVSVPAKPERRPSLPPSKQANKNLILKAISEAQESVTKTTNYSAVPQKQTLPVAPRTRTSQEELLAEMVQGQNRAPRISPPVKEEEAKGDNTGKSQGTQQRQLLSRLQIDPVMVETMEMSQDYYDMESMVHADTRSFILKKPKLSEEIVVTPNQDSGMKTADALRVLSGHLMQTRDLVQPDKPASPKFIVTLDGVPSPPGYMSDQEEEMCFEGMKPVNQTSASNKGLRGLLHPQQLHLLSRQLEDPDGSFSNAEMTDLSVAQKPEKLLERCKYWPACKNGDECVYHHPISPCKAFPNCKFAEKCLFVHPNCKYDTKCTKADCPFTHMSRRASILTPKPVSSPAPSSNGQLCRYFPACKKMECPFYHPKHCRFNTQCTRPDCTFYHPTITVPPRHALKWIRPQSSE", "length": 735 }, "evidence": [ { "id": "RGD:621850", "url": "https://alliancegenome.org/gene/RGD:621850#orthology", "database": "AGR" }, { "id": "MGI:1919824", "url": "https://alliancegenome.org/gene/MGI:1919824#orthology", "database": "AGR" }, { "id": "HGNC:20509", "url": "https://alliancegenome.org/gene/HGNC:20509#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-257", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-257#orthology", "database": "AGR" }, { "id": "FB:FBgn0028471", "url": "https://alliancegenome.org/gene/FB:FBgn0028471#orthology", "database": "AGR" }, { "id": "SGD:S000003090", "url": "https://alliancegenome.org/gene/SGD:S000003090#orthology", "database": "AGR" }, { "id": "Q5TYQ8", "url": "https://omabrowser.org/oma/group/Q5TYQ8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V3H9-1", "protein_name": "Zinc finger CCCH domain-containing protein 14", "gene_name": "Nab2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MECNLGSEIGQKMRSAVKAKLLELGTGGSAGFIDDELPDYVMVMVANKRTKQQMNAELNLFLGDQTDLFVTWLHEVLQKLQEVTLPTSSASSKKRKSRGQEKDKKGSKKDKRPHRKSGDELSEPQPSSSDAMPIVSSITDVFAEELLEKAKKTMDIDLSAKDEILHKKKNRKSIEDEDASANRALDVPAVSEIISTTIGVNRQKDLAELAEIQKKIHAAKKHLRQIGEIGDESDEYDEDLLNLSAREESVDQEPEEDPPKLEAPPRKAKSPIIFNRREKTPEKRPEAEPEIDSRQEEAEEKSPKKDSSADKAKEDRSERRSVHDRLGSKAQTPADRSQRNQKELYVPTHRRRSEPEATKERSQRERTRERRSSRDTSRDTNRNQRQRRSPSPEAPSTKQRIVSQVIVAVNKPPEPSDDEDMAEKPVNSVIKVKPRPNVSPRRQACKNLLLRAVADAQRSTILAKTSTQKEDEDVGKIISSLGKRKSEDKNDQIRKRNRERKRRKRSAQGNELFRRTTRELVVNVTQRDGKRERRSNERRAEIKVVEEEYTPSLMTEGVETYVPQLLTNVDELDLHISSHDEPSPNSGALKTQFVVTLNGDKALGGKNVKGGASRKRPSNSRKRSTSPVSTPQVSSSNIEPTSTTVDKRRRSNRDRSFSPSPRQSSGSPSLPTTRSINRNEVRRQPQEIKKIIIKNDTDEDDEMHGSPKKRSPNKRQPAAANGHKDNKDKGKIEEGSTTPPLPAKPKARAEKKASSKEKSVRSNSAETSSAAKSVSASTSVSTTTKAKHTPIRFTLKSEDEPSASKKRRSGSPDRDVAAPERRRVSIRNPEDRKYDNLPALSAVSVDSTVLKVNKPKERCKYHPNCTKQFCEYYHPTAPCKSFPNCKFADKCMYSHPKCKFDMACMSIDCNYAHGGQRDLSHVQLAAPPLSSHVIPVQNYKSISAPVTSTTATTMCKYYPNCSKLGCTFYHPKPCRFGKNCVNKLECIFYHPEMQSKFKWVASLG", "length": 1004 }, "evidence": [ { "id": "RGD:621850", "url": "https://alliancegenome.org/gene/RGD:621850#orthology", "database": "AGR" }, { "id": "MGI:1919824", "url": "https://alliancegenome.org/gene/MGI:1919824#orthology", "database": "AGR" }, { "id": "HGNC:20509", "url": "https://alliancegenome.org/gene/HGNC:20509#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-257", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-257#orthology", "database": "AGR" }, { "id": "FB:FBgn0028471", "url": "https://alliancegenome.org/gene/FB:FBgn0028471#orthology", "database": "AGR" }, { "id": "SGD:S000003090", "url": "https://alliancegenome.org/gene/SGD:S000003090#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "pre-mRNA binding", "id": "GO:0036002", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036002", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ8", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ8", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ], "pmid": "" }, { "name": "poly(A) binding", "id": "GO:0008143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008143", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ8", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ8", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ8", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ], "pmid": "" }, { "name": "nuclear speck", "id": "GO:0016607", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016607", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ8", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ8", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ], "pmid": "" }, { "name": "regulation of mRNA stability", "id": "GO:0043488", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043488", "evidence": [ { "database": "UniProtKB", "id": "Q5TYQ8", "url": "https://www.uniprot.org/uniprotkb/Q5TYQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 495, "end_pos": 497, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 314, "end_pos": 316 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 495, "end_pos": 497 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5TYS5-1", "uniprot_ac": "Q5TYS5", "uniprot_id": "SCRN2_DANRE", "mass": { "chemical_mass": 46041.0, "monoisotopic_mass": 46041.0 }, "refseq": { "ac": "NP_001025287", "name": "secernin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025287" }, "gene_names": [ { "name": "scrn2", "type": "recommended", "evidence": [ { "id": "Q5TYS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5" } ] }, { "name": "scrn2", "type": "synonym", "evidence": [ { "id": "NP_001025287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025287" } ] }, { "name": "si:ch211-184m19.2", "type": "synonym", "evidence": [ { "id": "NP_001025287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025287" }, { "id": "Q5TYS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5" } ] } ], "protein_names": [ { "name": "Secernin-2", "type": "recommended", "evidence": [ { "id": "Q5TYS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5/entry#names_and_taxonomy" } ] }, { "name": "secernin-2", "type": "synonym", "evidence": [ { "id": "NP_001025287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025287" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC124746.1, GFIL01034625.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. On Aug 6, 2005 this sequence version replaced XP_686598.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025287" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TYS5", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "scrn2", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040724-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-75", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5TYS5", "url": "https://alphafold.ebi.ac.uk/entry/Q5TYS5", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000043497", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000043497", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "558306", "url": "https://www.ncbi.nlm.nih.gov/gene/558306", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558306", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558306", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QAQGWWG", "url": "https://omabrowser.org/oma/group/QAQGWWG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5TYS5", "url": "https://www.orthodb.org/?gene=Q5TYS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12994", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12994", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12994:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12994:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03577", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03577", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5TYS5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5TYS5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001025287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025287", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58I3L9", "url": "https://www.uniprot.org/uniprotkb/A0AC58I3L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I3L9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I3L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TYS5", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TYS5-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040724-75", "url": "https://zfin.org/ZDB-GENE-040724-75", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAEPPRSCDCFVSLPPGSKEDYVIFGKNSDRPRDEVQEVVYFPASSHPPASTVECTYISIPQVEHTNAVVLSRPAWLWGAEMGANEHGVCVGNEAVWTKEPVNPEEALLGMDLVRLGLERGDSARAALNVITALLEQFGQGGACRETSEPFSYHNTFLLVDRQEAWVLETAGKLWAAQKVTEGVKNISNQLTIDFEISAEHPDLRSVAQAQGWWSGEGDFSFTAVFSPDHPPARMEMAKQRYRGGTALLQQHNGSVTAEVMMSILRDKASGICMDSEGFRTTGSMVSILPRNPNMPCVHFLTATPDPSRSVFKPFIFSESVRPVSMVMSPQYGPGDPVRTLPRFQHQVDRKHELYKAHQMANTSSDAGVSLQDTMRYLESQCLEEIEAMLRGEVQGQELGDLFFDCVDAEIKFYQ", "length": 415, "header": "sp|Q5TYS5-1|SCRN2_DANRE Isoform 1 of Secernin-2 OS=Danio rerio OX=7955 GN=scrn2 PE=2 SV=1 CANONICAL=Q5TYS5-1" }, "isoforms": [ { "isoform_ac": "A0AC58I3L9-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5/entry#A0AC58I3L9-1", "sequence": { "sequence": "MQCTYISIPQVEHTNAVVLSRPAWLWGAEMGANEHGVCVGNEAVWTKEPVNPEEALLGMDLVRLGLERGDSARAALNVITALLEQFGQGGACRETSEPFSYHNTFLLVDRQEAWVLETAGKLWAAQKVTEGVKNISNQLTIDFEISAEHPDLRSVAQAQGWWSGEGDFSFTAVFSPDHPPARMEMAKQRYRGGTALLQQHNGSVTAEVMMSILRDKASGICMDSEGFRTTGSMVSILPRNPNMPCVHFLTATPDPSRSVFKPFIFSESVRPVSMVMSPQYGPGDPVRTLPRFQHQVDRKHELYKAHQMANTSSDAGVSLQDTMRYLESQCLEEIEAMLRGEVQGQELGDLFFDCVDAEIKFYQ", "length": 363, "header": "tr|A0AC58I3L9-1|A0AC58I3L9_DANRE Computationally mapped isoform of Secernin-2 OS=Danio rerio OX=7955 GN=scrn2 PE=1 SV=1 CANONICAL=Q5TYS5-1" }, "locus": {} }, { "isoform_ac": "Q5TYS5-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5/entry#Q5TYS5-1", "sequence": { "sequence": "MAEPPRSCDCFVSLPPGSKEDYVIFGKNSDRPRDEVQEVVYFPASSHPPASTVECTYISIPQVEHTNAVVLSRPAWLWGAEMGANEHGVCVGNEAVWTKEPVNPEEALLGMDLVRLGLERGDSARAALNVITALLEQFGQGGACRETSEPFSYHNTFLLVDRQEAWVLETAGKLWAAQKVTEGVKNISNQLTIDFEISAEHPDLRSVAQAQGWWSGEGDFSFTAVFSPDHPPARMEMAKQRYRGGTALLQQHNGSVTAEVMMSILRDKASGICMDSEGFRTTGSMVSILPRNPNMPCVHFLTATPDPSRSVFKPFIFSESVRPVSMVMSPQYGPGDPVRTLPRFQHQVDRKHELYKAHQMANTSSDAGVSLQDTMRYLESQCLEEIEAMLRGEVQGQELGDLFFDCVDAEIKFYQ", "length": 415, "header": "sp|Q5TYS5-1|SCRN2_DANRE Isoform 1 of Secernin-2 OS=Danio rerio OX=7955 GN=scrn2 PE=2 SV=1 CANONICAL=Q5TYS5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "Q5TYS5", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:558306", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558306", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K189-1", "protein_name": "Secernin 3", "gene_name": "Scrn3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPYSCDTFVALPPATVGNRVIFGKNSDRLFDEVQEVIYFPAAVHSDLEKRLKCTYIEVDQVPETYAVVLSRPAWLWGAEMGANEHGVCIGNEAIWGREDISKEEALLGMDLVRLGLERADTAEKALNVIVDLLGKYGQGGNCAEGEEFSYYNSFLIADRNEAWILETSGKFWAAEKVQGVRNISNQFSITTKIDREHPDMRNYAKQRGWWDGKEEFDFAAAYSYTDTATMMTSPSRYCQGHKLLNKHKGNITYETMVEILRDRPSGINMKGEFLTTASMVSILPQDPSLPCIHLLTGTPHPERSVFKPFIFVPHVSPLLDTKSPTFELERPVAKKPYVKPDRRHLLYQNHQQALEMISNHKEKGKTILDNVRKLEKEVFEEIESILQNRHLDMDKTVNLFPQYVRDEIKIYQPNISS", "length": 418 }, "evidence": [ { "id": "FB:FBgn0037472", "url": "https://alliancegenome.org/gene/FB:FBgn0037472#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A287BJ40-1", "protein_name": "Secernin-2", "gene_name": "SCRN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASWSPDTPCSCDCFVSVPPASAIPAVIFAKNSDRPRDEVQEVVFVPAGTHAPGSRLQCTYIEVEQVPKTHAVILSRPSWLWGAEMGANEHGVCIGNEAVWTKEPVGEGEALLGMDLLRLALERGSSAQEALHVITGLLERYGQGGSCREDPTPFCYHNTFLLADRTEAWVLETAGRLWAAQRIQAGARNISNQLSIGTDLSAEHPKLRPHARAQGWWDGQGAFDFAQAFSLTQQPVRMEAAKARFQAGRLLLQQKQGAITAEVMMGILRDKASGICMDSGGFRTTASMVSLLPRDPTQPCVHFLTATPDPARSVFKPFIFGVGAAQAPLVLSPTFGAQDPVQTLPRFQTRVDRRHTLYCRHQVALGLMESEQDRGQQLRQKQQDLEQEGLEAVRGLLAGEWAPRPQELGGLFQAFVEKESQAYA", "length": 425 }, "evidence": [ { "id": "Q5TYS5", "url": "https://omabrowser.org/oma/group/Q5TYS5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZU99-1", "protein_name": "Secernin-2", "gene_name": "SCRN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGHDPAPSCCDCFVALPPHTAAPAVVFGKNADRPRHEVQEIAYIPSAVHRPGDKVQCTYIEIEQAERTHAVVLSRPAWLWGAEMGANEHGVCVGNEGVWTREPVGEGEALLGMDLVRLGLERGGSAREALEVITALLEQHGQGGSCKEEPIPFVYHNTFLLADRHEAWVLETAGRYWAAQQIREGSRNISNQLSIGTDITAEHPGLRQRAQSQGWWSGVGQFSFAEVFSLAQQPPRMEAAKSRYRAGKELLQQHAGRITAETFMAILRDKDSGICVDSEGFRTAGSMVSVLPQDPALPCVHFFTATPDPSRSVFKPFVFVPGLKPAPQVSSPTFSDDPAKKVPRFQSTVDRRHELYCRHQAALELMEKDQERGQELLQTLRDLEKQGLEAVNALLAGNVAPKPEELAELFFDCVDAEMKFYK", "length": 423 }, "evidence": [ { "id": "Q5TYS5", "url": "https://omabrowser.org/oma/group/Q5TYS5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q0VDG4-1", "protein_name": "Secernin-3", "gene_name": "SCRN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPFSCDTFVALPPATVDNRIIFGKNSDRLYDEVQEVVYFPAVVHDNLGERLKCTYIEIDQVPETYAVVLSRPAWLWGAEMGANEHGVCIGNEAVWGREEVCDEEALLGMDLVRLGLERADTAEKALNVIVDLLEKYGQGGNCTEGRMVFSYHNSFLIADRNEAWILETAGKYWAAEKVQEGVRNISNQLSITTKIAREHPDMRNYAKRKGWWDGKKEFDFAAAYSYLDTAKMMTSSGRYCEGYKLLNKHKGNITFETMMEILRDKPSGINMEGEFLTTASMVSILPQDSSLPCIHFFTGTPDPERSVFKPFIFVPHISQLLDTSSPTFELEDLVKKKSHFKPDRRHPLYQKHQQALEVVNNNEEKAKIMLDNMRKLEKELFREMESILQNKHLDVEKIVNLFPQCTKDEIQIYQSNLSVKVSS", "length": 424 }, "evidence": [ { "id": "FB:FBgn0037472", "url": "https://alliancegenome.org/gene/FB:FBgn0037472#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q12765-1", "protein_name": "Secernin-1", "gene_name": "SCRN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAPPSYCFVAFPPRAKDGLVVFGKNSARPRDEVQEVVYFSAADHEPESKVECTYISIDQVPRTYAIMISRPAWLWGAEMGANEHGVCIANEAINTREPAAEIEALLGMDLVRLGLERGETAKEALDVIVSLLEEHGQGGNYFEDANSCHSFQSAYLIVDRDEAWVLETIGKYWAAEKVTEGVRCICSQLSLTTKMDAEHPELRSYAQSQGWWTGEGEFNFSEVFSPVEDHLDCGAGKDSLEKQEESITVQTMMNTLRDKASGVCIDSEFFLTTASGVSVLPQNRSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKTQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAIIESDQEQGRKLRSTMLELEKQGLEAMEEILTSSEPLDPAEVGDLFYDCVDTEIKFFK", "length": 414 }, "evidence": [ { "id": "FB:FBgn0037472", "url": "https://alliancegenome.org/gene/FB:FBgn0037472#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TMH2-1", "protein_name": "Secernin-3", "gene_name": "Scrn3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPYSCDTFVALPPATVGNRVIFGKNSDRLFDEVQEVIYCPAAVHNDLEKRLKCTYIEVDQVPETYAVVLSRPAWLWGAEMGANEHGVCIGNEAVWGREDISKEEALLGMDLVRLGLERADTAEKALDVIVDLLEKYGQGGNCAEGKEFSYYNSFLIADRNEAWILETSGKYWAAERVQGVRNISNQLSITTKIDREHPDMRNYAKQRGWWDGKEEFDFTAAYSYIDTAAMMTSPSRYCQGYKLLDKHRGNITFETMMEILRDRPSGINMKGEFLTTASMVSVLPQDPSLPCIHLFTATPHPERSVFKPFIFVPHISPLLDTKSPTFEPERPVAKKPYVKPDRRHPLYQKHQEALEMISNSKEKGKTILDKMRKLEKAVSEEIESILQSGHLDEEKTVNLFPQYVKDEIKIYQSNISS", "length": 418 }, "evidence": [ { "id": "FB:FBgn0037472", "url": "https://alliancegenome.org/gene/FB:FBgn0037472#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6AY84-1", "protein_name": "Secernin-1", "gene_name": "Scrn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGAPPSYSFVALPPRAKDGLVVFGKNSARPRDEVQEVVYFPAVDHEAESKVECTYISIDQVPRTHAIVISRPAWLWGAEMGANEHGVCIANEAINAREPAAETEALLGMDLVRLGLERGTTAKEALDIIVSLLDEHGQGGNYYEDAHSCHSFQSAYLLVDRDEAWVLETVGKYWAAERITEGVRCICNHLSLTTKMDEEHPELRTYAQSQGWWTGEDEFNFAQVFSPADDHLDCCAGKDSLEKQEESITVQTMINILRDKASGVCIDSESFLTTASIVSVLPQNRSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKAQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAVIESDQEQGRTLRKTMLELEKQGLEAMEEILSSPEPPDPAEVGDLFYDCVDTEMKFFK", "length": 414 }, "evidence": [ { "id": "FB:FBgn0037472", "url": "https://alliancegenome.org/gene/FB:FBgn0037472#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AYR8-1", "protein_name": "Secernin-2", "gene_name": "Scrn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSSPDAPCSCDCFVSVPPASAIPAVIFAKNSDRPRDEVQEVVFIPAGTHTPGSRLQCTYIEVEQVWKTHAVILSRPSWLWGAEMGANELGVCIGNEAVWTKEPVGEGEALLGMDLLRLALERSSTAQAAVHVIAGLLDRYGQGGSCREDPEPFCYHNTFLLADRTEAWVLETAGRLWAAQRIQGGARNISNQLSIGTDISAEHPELRSHAKAQGWWSGQGVFDFAEVFSLTQQPVRMEAAKARFRAGCEMLQRQQGSITAEVMMDILRNKESGICMDSGGFRTTASMVSVLPQDPTKPCVHFLTATPDPSRSVFKPFIFEVGVSQPPQVLSPTFGAQDPVRILPRFQTQVDRRHSLYRGHQAALGLMDEQEQAQLRQEQQSLEQEGLEALRGLLTGEQTPAPQELGSLFQAFVEREHQVYA", "length": 423 }, "evidence": [ { "id": "HGNC:30381", "url": "https://alliancegenome.org/gene/HGNC:30381#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-75#orthology", "database": "AGR" }, { "id": "RGD:1307741", "url": "https://alliancegenome.org/gene/RGD:1307741#orthology", "database": "AGR" }, { "id": "MGI:1343092", "url": "https://alliancegenome.org/gene/MGI:1343092#orthology", "database": "AGR" }, { "id": "FB:FBgn0037472", "url": "https://alliancegenome.org/gene/FB:FBgn0037472#orthology", "database": "AGR" }, { "id": "Q5TYS5", "url": "https://omabrowser.org/oma/group/Q5TYS5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q803W1-1", "protein_name": "Secernin-3", "gene_name": "scrn3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYPRSCDTFVALPPSTEGQRIIFGKNSDRPCDEVQEVVYFPAKEHEPGKVECTYIEIEQVEKTFAVVLSRPAWLWGAEMGANEHQVCIGNEAVWGRESADGDEALLGMDLVRLALERADTAEKAVDVITDLLEKYGQGGNCMEDECGFTYHNSFLISDRKEAWVLETAGKHWAAERVEAGYRNISNQYSITTKIDKEHPGMRTYAKEQGWWDGESEFSFTDVYSYSSTARIQAAGGRYCEGQKLLQKSNGHISAQTMMDILRDKESGINMEGMFMSTGSMVSVIPKADHLPGVHFFTATPDPERSVFKPFVFVSDVPPLKHTSSPCFGEEDPVKKKPRFQSKPNRKHPLFLKHEVAAAIIDSSGERGQKIEKEMRDLEKQKLEEMEKYLTEGVEDSSLLVHLFTDTVEEEFSVYSSA", "length": 417 }, "evidence": [ { "id": "FB:FBgn0037472", "url": "https://alliancegenome.org/gene/FB:FBgn0037472#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8VCA8-1", "protein_name": "Secernin-2", "gene_name": "Scrn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSSPDAPCSCDCFVSVPPASAIPAVIFAKNSDRPRDEVQEVVFIPAGTHVPGSRLQCTYIEVEQVGKTHAVILSRPSWLWGAEMGANELGVCIGNEAVWTKEPVGQGEALLGMDLLRLALERSSTAQEAVHVIAGLLDRYGQGGSCREDPEPFCYHNTFLLADRTEAWVLETAGSLWAAQRIQGGARNISNQLSIGTDISAEHPELRSHAKAQGWWTGQGLFDFAEVFSLTQQPVRMEAAKARFRAGCEMLQRHQGNITAEVMMGILRDKESGICMDSGGFRTTASMVSVLPQDPTKPCVHFLTATPDPSRSVFKPFIFEVGVSQSPQVLSPTFGAQDPVRILPRFQTRVDRRHSLYRGHQAALGLMEDEQEQAQQLRKKQQRLEQEGLEALRGLLTGEQTPPAQGLGSLFQAFVEREEQAYA", "length": 425 }, "evidence": [ { "id": "HGNC:30381", "url": "https://alliancegenome.org/gene/HGNC:30381#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-75#orthology", "database": "AGR" }, { "id": "RGD:1307741", "url": "https://alliancegenome.org/gene/RGD:1307741#orthology", "database": "AGR" }, { "id": "MGI:1343092", "url": "https://alliancegenome.org/gene/MGI:1343092#orthology", "database": "AGR" }, { "id": "FB:FBgn0037472", "url": "https://alliancegenome.org/gene/FB:FBgn0037472#orthology", "database": "AGR" }, { "id": "Q5TYS5", "url": "https://omabrowser.org/oma/group/Q5TYS5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96FV2-1", "protein_name": "Secernin-2", "gene_name": "SCRN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSSPDSPCSCDCFVSVPPASAIPAVIFAKNSDRPRDEVQEVVFVPAGTHTPGSRLQCTYIEVEQVSKTHAVILSRPSWLWGAEMGANEHGVCIGNEAVWTKEPVGEGEALLGMDLLRLALERSSSAQEALHVITGLLEHYGQGGNCLEDAAPFSYHSTFLLADRTEAWVLETAGRLWAAQRIQEGARNISNQLSIGTDISAQHPELRTHAQAKGWWDGQGAFDFAQIFSLTQQPVRMEAAKARFQAGRELLRQRQGGITAEVMMGILRDKESGICMDSGGFRTTASMVSVLPQDPTQPCVHFLTATPDPSRSVFKPFIFGMGVAQAPQVLSPTFGAQDPVRTLPRFQTQVDRRHTLYRGHQAALGLMERDQDRGQQLQQKQQDLEQEGLEATQGLLAGEWAPPLWELGSLFQAFVKRESQAYA", "length": 425 }, "evidence": [ { "id": "HGNC:30381", "url": "https://alliancegenome.org/gene/HGNC:30381#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-75#orthology", "database": "AGR" }, { "id": "RGD:1307741", "url": "https://alliancegenome.org/gene/RGD:1307741#orthology", "database": "AGR" }, { "id": "MGI:1343092", "url": "https://alliancegenome.org/gene/MGI:1343092#orthology", "database": "AGR" }, { "id": "FB:FBgn0037472", "url": "https://alliancegenome.org/gene/FB:FBgn0037472#orthology", "database": "AGR" }, { "id": "Q5TYS5", "url": "https://omabrowser.org/oma/group/Q5TYS5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZC8-1", "protein_name": "Secernin-1", "gene_name": "Scrn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGAPPSYSFVALPPRAKDGLVVFGKNSARPRDEVQEVVYFPAVDHDAESKVECTYISIDQVPRTHAIVISRPAWLWGAEMGANEHGVCIANEAINAREPAAETEALLGMDLVRLGLERGTTAKEALDIIVSLLDEHGQGGNYYEDAHSCHSFQSAYLLVDRDEAWVLETVGKYWAAERITEGVRCICNHLSLATKLDEEHPELRTYAQSQGWWTGDDEFNFAQVFSPADDRLDCCAGQDSLEKQEESITVQTMINILRDKASGVCIDSESFLTTASIVSVLPQNRSSPCIHYFTGTPDPSRSIFKPFIFVDDVKLVPKAQSPCFGDDDPAKKEPRFQEKPDRRHELYKAHEWARAVIESDEEQGRTLRKTMLELEKQGLEAMDEILSSPEPPDPAEVGDLFYDCVDTEMKFFK", "length": 414 }, "evidence": [ { "id": "FB:FBgn0037472", "url": "https://alliancegenome.org/gene/FB:FBgn0037472#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VI64-1", "protein_name": "Secernin-3", "gene_name": "Dmel\\CG10098", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTNGDCFVVLPENCAEGTLIIGRNAEDEKNVNVASEVCFYDATEVLEGKTDGGASAETGGDMLRVILQKPQPGLWGGDFGANERGVALGLTWAAGENEAKDSDSLLGTDIVRLTLAVAKDVDDAVDRIGALVASHGHDNSKLNFIACDAAAAWLVSCSGKVWAAEKLEASFLRLPSGGLAVTTVVNKSSEGLDDAASFAAAHDAEAQAPAVDWCGPKPAGDGTYTQHDMFETLRSASNASSSRAATVSVLSVKGISCHWFTGTPNAAESVFKPFVFAPNPRISPLTQVQAEADLTLLHKLHSQRKPAALEHLRSLELSCVDELNNYFSLQDHASDELDELLKDCVEAEVKFYR", "length": 353 }, "evidence": [ { "id": "HGNC:30381", "url": "https://alliancegenome.org/gene/HGNC:30381#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-75#orthology", "database": "AGR" }, { "id": "RGD:1307741", "url": "https://alliancegenome.org/gene/RGD:1307741#orthology", "database": "AGR" }, { "id": "MGI:1343092", "url": "https://alliancegenome.org/gene/MGI:1343092#orthology", "database": "AGR" }, { "id": "FB:FBgn0037472", "url": "https://alliancegenome.org/gene/FB:FBgn0037472#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "Q5TYS5", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "dipeptidase activity", "id": "GO:0016805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016805", "evidence": [ { "database": "UniProtKB", "id": "Q5TYS5", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5" } ], "pmid": "" }, { "name": "cysteine-type exopeptidase activity", "id": "GO:0070004", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070004", "evidence": [ { "database": "UniProtKB", "id": "Q5TYS5", "url": "https://www.uniprot.org/uniprotkb/Q5TYS5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 362, "end_pos": 364 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ 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"Protein" ] }, { "id": "ZDB-GENE-030131-1024", "url": "https://zfin.org/ZDB-GENE-030131-1024", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFLQSTENDMRFKPSRDRLYSARCCGCCHVRTGTIILGTWYMVVNLLMGILLTVAVTHPENVPTVDLQYEVIEHYFASDRMSENACVGFAISLLMLTISAMMVYGAITNRDGWLIPFFCYQLFDFALSCLVAISSLTYLPRIKDYLDQLPDFPYKDNLLSLDSSCLLLFVLIFFAILIVLKAYLINCVWNCYKYINNRNTPEIAVYPAFETPPQYILPTYEMAMTMPAKEPPPPYMPA", "length": 238, "header": "tr|Q5TYX5-1|Q5TYX5_DANRE Isoform 1 of Lysosomal-associated transmembrane protein 4A OS=Danio rerio OX=7955 GN=laptm4a PE=3 SV=1 CANONICAL=Q5TYX5-1" }, "isoforms": [ { "isoform_ac": "Q5TYX5-1", "url": "https://www.uniprot.org/uniprotkb/Q5TYX5/entry#Q5TYX5-1", "sequence": { "sequence": "MFLQSTENDMRFKPSRDRLYSARCCGCCHVRTGTIILGTWYMVVNLLMGILLTVAVTHPENVPTVDLQYEVIEHYFASDRMSENACVGFAISLLMLTISAMMVYGAITNRDGWLIPFFCYQLFDFALSCLVAISSLTYLPRIKDYLDQLPDFPYKDNLLSLDSSCLLLFVLIFFAILIVLKAYLINCVWNCYKYINNRNTPEIAVYPAFETPPQYILPTYEMAMTMPAKEPPPPYMPA", "length": 238, "header": "tr|Q5TYX5-1|Q5TYX5_DANRE Isoform 1 of Lysosomal-associated transmembrane protein 4A OS=Danio rerio OX=7955 GN=laptm4a PE=3 SV=1 CANONICAL=Q5TYX5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish gene map defines ancestral vertebrate chromosomes.", "journal": "Genome Res.", "date": "2005", "authors": "Woods Ian G, Wilson Catherine, Friedlander Brian, Chang Patricia, Reyes Daengnoy K, Nix Rebecca, Kelly Peter D, Chu Felicia, Postlethwait John H, Talbot William S", "evidence": [ { "database": "UniProtKB", "id": "Q5TYX5", "url": "https://www.uniprot.org/uniprotkb/Q5TYX5" } ], "reference": [ { "type": "PubMed", "id": "16109975", "url": "https://glygen.org/publication/PubMed/16109975" } ] }, { "title": "In vivo imaging of molecular interactions at damaged sarcolemma.", "journal": "Dev. 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"title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5TZ05-1", "uniprot_ac": "Q5TZ05", "uniprot_id": "Q5TZ05_DANRE", "mass": { "chemical_mass": 26625.0, "monoisotopic_mass": 26625.0 }, "refseq": { "ac": "NP_001076362", "name": "mitochondrial peptide methionine sulfoxide reductase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076362" }, "gene_names": [ { "name": "msraa", "type": "recommended", "evidence": [ { "id": "Q5TZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" } ] }, { "name": "msraa", "type": "synonym", "evidence": [ { "id": "NP_001076362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076362" } ] }, { "name": "msra", "type": "synonym", "evidence": [ { "id": "NP_001076362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076362" }, { "id": "Q5TZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" } ] }, { "name": "si:dkey-221h15.1", "type": "synonym", "evidence": [ { "id": "NP_001076362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076362" }, { "id": "Q5TZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" } ] } ], "protein_names": [ { "name": "Mitochondrial peptide methionine sulfoxide reductase", "type": "recommended", "evidence": [ { "id": "Q5TZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05/entry#names_and_taxonomy" } ] }, { "name": "1.8.4.11", "type": "synonym", "evidence": [ { "id": "Q5TZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05/entry#names_and_taxonomy" } ] }, { "name": "Peptide-methionine (S)-S-oxide reductase", "type": "synonym", "evidence": [ { "id": "Q5TZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05/entry#names_and_taxonomy" } ] }, { "name": "Protein-methionine-S-oxide reductase", "type": "synonym", "evidence": [ { "id": "Q5TZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05/entry#names_and_taxonomy" } ] }, { "name": "methionine sulfoxide reductase A", "type": "synonym", "evidence": [ { "id": "NP_001076362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076362" } ] }, { "name": "mitochondrial peptide methionine sulfoxide reductase", "type": "synonym", "evidence": [ { "id": "NP_001076362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076362" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH573383.1, EH499139.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. On Mar 15, 2007 this sequence version replaced XP_001333766.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001076362", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076362" } ] }, { "annotation": "Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Plays a crucial role in repairing oxidized methionine residues in key lens proteins, such as alpha-crystallin (CRYAA/CRYAB) and cytochrome c (CYCS), thereby restoring their function and maintaining lens transparency.", "evidence": [ { "database": "UniProtKB", "id": "A0AC58I534", "url": "https://www.uniprot.org/uniprotkb/A0AC58I534#function" }, { "database": "UniProtKB", "id": "ARBA00094335", "url": "https://www.uniprot.org/uniprotkb/ARBA00094335#function" }, { "database": "UniProtKB", "id": "A0AC58I545", "url": "https://www.uniprot.org/uniprotkb/A0AC58I545#function" }, { "database": "UniProtKB", "id": "Q5TZ05", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TZ05", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "msraa", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041014-344", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-344", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000029587", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000029587", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "793910", "url": "https://www.ncbi.nlm.nih.gov/gene/793910", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036509", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036509", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:793910", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793910", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LFWESHD", "url": "https://omabrowser.org/oma/group/LFWESHD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5TZ05", "url": "https://www.orthodb.org/?gene=Q5TZ05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42799", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42799", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42799:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42799:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-5676934", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5676934", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001076362", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076362", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "14217", "url": "https://www.rhea-db.org/rhea/14217", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "19993", "url": "https://www.rhea-db.org/rhea/19993", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AC58I534", "url": "https://www.uniprot.org/uniprotkb/A0AC58I534", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I534-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I534-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I545", "url": "https://www.uniprot.org/uniprotkb/A0AC58I545", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I545-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I545-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TZ05", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TZ05-1", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041014-344", "url": "https://zfin.org/ZDB-GENE-041014-344", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVARTSVRLIWRQFIQSRMGEMSSKVQMISPEEALPGREQSIKVSAKHDVNGNRTVPPFPEGLQMVLFGMGCFWGAERKFWRQKGVYSTQVGYSGGYTPNPTYEEVCTGKTGHTEVVRVVFEPQKIKFSELLKVFWESHNPTQGMRQGNDVGTTYRSSIYTNTQEQLEQALQSREEYQKVLTEEGFGAITTEITMAKEFYYAEDYHQQYLSKNPDGYCGLGGTGVSCPIGLKSKH", "length": 235, "header": "tr|Q5TZ05-1|Q5TZ05_DANRE Isoform 1 of Mitochondrial peptide methionine sulfoxide reductase OS=Danio rerio OX=7955 GN=msraa PE=1 SV=1 CANONICAL=Q5TZ05-1" }, "isoforms": [ { "isoform_ac": "A0AC58I534-1", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05/entry#A0AC58I534-1", "sequence": { "sequence": "MDFLWVLRFPHSPKTCARAKHDVNGNRTVPPFPEGLQMVLFGMGCFWGAERKFWRQKGVYSTQVGYSGGYTPNPTYEEVCTGKTGHTEVVRVVFEPQKIKFSELLKVFWESHNPTQGMRQGNDVGTTYRSSIYTNTQEQLEQALQSREEYQKVLTEEGFGAITTEITMAKEFYYAEDYHQQYLSKNPDGYCGLGGTGVSCPIGLKSKH", "length": 208, "header": "tr|A0AC58I534-1|A0AC58I534_DANRE Computationally mapped isoform of Mitochondrial peptide methionine sulfoxide reductase OS=Danio rerio OX=7955 GN=msraa PE=1 SV=1 CANONICAL=Q5TZ05-1" }, "locus": {} }, { "isoform_ac": "A0AC58I545-1", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05/entry#A0AC58I545-1", "sequence": { "sequence": "MVLFGMGCFWGAERKFWRQKGVYSTQVGYSGGYTPNPTYEEVCTGKTGHTEVVRVVFEPQKIKFSELLKVFWESHNPTQGMRQGNDVGTTYRSSIYTNTQEQLEQALQSREEYQKVLTEEGFGAITTEITMAKEFYYAEDYHQQYLSKNPDGYCGLGGTGVSCPIGLKSKH", "length": 171, "header": "tr|A0AC58I545-1|A0AC58I545_DANRE Computationally mapped isoform of Mitochondrial peptide methionine sulfoxide reductase OS=Danio rerio OX=7955 GN=msraa PE=1 SV=1 CANONICAL=Q5TZ05-1" }, "locus": {} }, { "isoform_ac": "Q5TZ05-1", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05/entry#Q5TZ05-1", "sequence": { "sequence": "MVARTSVRLIWRQFIQSRMGEMSSKVQMISPEEALPGREQSIKVSAKHDVNGNRTVPPFPEGLQMVLFGMGCFWGAERKFWRQKGVYSTQVGYSGGYTPNPTYEEVCTGKTGHTEVVRVVFEPQKIKFSELLKVFWESHNPTQGMRQGNDVGTTYRSSIYTNTQEQLEQALQSREEYQKVLTEEGFGAITTEITMAKEFYYAEDYHQQYLSKNPDGYCGLGGTGVSCPIGLKSKH", "length": 235, "header": "tr|Q5TZ05-1|Q5TZ05_DANRE Isoform 1 of Mitochondrial peptide methionine sulfoxide reductase OS=Danio rerio OX=7955 GN=msraa PE=1 SV=1 CANONICAL=Q5TZ05-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ05", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ05", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Inter-species functional interactome of nuclear steroid receptors (R1).", "journal": "Front. Biosci. (Elite Ed.)", "date": "2018", "authors": "Geronikolou Styliani A, Pavlopoulou Athanasia, Kanaka-Gantenbein Christina, Chrousos George", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ05", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" } ], "reference": [ { "type": "PubMed", "id": "28930614", "url": "https://glygen.org/publication/PubMed/28930614" } ] } ], "pathway": [ { "id": "dre:793910", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793910", "resource": "KEGG Pathway" }, { "id": "R-DRE-5676934", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5676934", "resource": "Reactome", "description": "Protein repair" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RJP8-1", "protein_name": "Mitochondrial peptide methionine sulfoxide reductase", "gene_name": "MSRA", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFLAIRRANQLFHSVFPIRRMGDSASRIVRPQEALPGRKEPMAVEGKEAMSMDERGNRYKTEPQSLERKEHYCNEKDFNSLKSLETSILLFVSMNLTTLVTASKHHVNGNRTVEPFPEGTQMALFGMGCFWGAERKFWTLKGVYSTQAGFAGGYTPNPTYKEVCSGRTGHAEVVRVVYQPEHISFEELLKVFWENHDPTQGLRQGQDHGSQYRSAIYPTSAEHMEAALRSKEDYQKVLSEHGFGLITTDIREGQPFYYAEDYHQQYLSKNPDGYCGLGGTGVACPLGIRK", "length": 290 }, "evidence": [ { "id": "Q5TZ05", "url": "https://omabrowser.org/oma/group/Q5TZ05/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P08761-1", "protein_name": "Peptide methionine sulfoxide reductase", "gene_name": "MsrA", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLTITSSVTHPELKDLSTVRNEQKELNISPVHDVNVTKATATFGMGCFWGAESLYGATRGVLRTTVGYAGGSSDLPTYRKMGDHTEVLEIDYDPTVISFKELLDLFWNNHEYGLTTPIKRQYASLILYHDEEQKQVAHASKLEEQERRAPEIITTEIASKENFYPAEAYHQKYRLQGHKDLASSLNLSPKLLQTSYVATKLNGYLAGVGGIEQFKAEAETMGLTPTQRQYCYYHVEQNEGQGLYC", "length": 246 }, "evidence": [ { "id": "MGI:106916", "url": "https://alliancegenome.org/gene/MGI:106916#orthology", "database": "AGR" }, { "id": "HGNC:7377", "url": "https://alliancegenome.org/gene/HGNC:7377#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P40029-1", "protein_name": "Peptide methionine sulfoxide reductase", "gene_name": "MXR1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSLISKTIKYDPAKDKLITLACGCFWGTEHMYRKYLNDRIVDCKVGYANGEESKKDSPSSVSYKRVCGGDTDFAEVLQVSYNPKVITLRELTDFFFRIHDPTTSNSQGPDKGTQYRSGLFAHSDADLKELAKIKEEWQPKWGNKIATVIEPIKNFYDAEEYHQLYLDKNPQGYACPTHYLREM", "length": 184 }, "evidence": [ { "id": "MGI:106916", "url": "https://alliancegenome.org/gene/MGI:106916#orthology", "database": "AGR" }, { "id": "HGNC:7377", "url": "https://alliancegenome.org/gene/HGNC:7377#orthology", "database": "AGR" }, { "id": "Q5TZ05", "url": "https://omabrowser.org/oma/group/Q5TZ05/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P54149-1", "protein_name": "Mitochondrial peptide methionine sulfoxide reductase", "gene_name": "MSRA", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSATRRALQLFHSLFPIPRMGDSAAKIVSPQEALPGRKEPLVVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWTLKGVYSTQVGFAGGYTPNPTYKEVCSGKTGHAEVVRVVFQPEHISFEELLKVFWENHDPTQGMRQGNDHGSQYRSAIYPTSAEHVGAALKSKEDYQKVLSEHGFGLITTDIREGQTFYYAEDYHQQYLSKDPDGYCGLGGTGVSCPLGIKK", "length": 233 }, "evidence": [ { "id": "Q5TZ05", "url": "https://omabrowser.org/oma/group/Q5TZ05/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q923M1-1", "protein_name": "Mitochondrial peptide methionine sulfoxide reductase", "gene_name": "Msra", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSASRRTLQLLSSSIPVRMMGDSSSKVISAEEALPGRTESIPVAAKHHVSGNRTVEPFPEGTQMAVFGMGCFWGAERKFWLLKGVYSTQVGFAGGYTRNPTYKEVCSEKTGHAEVVRVVYRPEHVSFEELLKVFWENHDPTQGMRQGNDCGTQYRSAVYPTSAVQMEAALKSKEEYQKVLSKHGFGPITTDIREGQVFYYAEDYHQQYLSKNPDGYCGLGGTGVSCPTAIKK", "length": 233 }, "evidence": [ { "id": "MGI:106916", "url": "https://alliancegenome.org/gene/MGI:106916#orthology", "database": "AGR" }, { "id": "HGNC:7377", "url": "https://alliancegenome.org/gene/HGNC:7377#orthology", "database": "AGR" }, { "id": "Q5TZ05", "url": "https://omabrowser.org/oma/group/Q5TZ05/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D6Y7-1", "protein_name": "Mitochondrial peptide methionine sulfoxide reductase", "gene_name": "Msra", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSASRRALQLLSSANPVRRMGDSASKVISAEEALPGRTEPIPVTAKHHVSGNRTVEPFPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGHTRNPTYKEVCSEKTGHAEVVRVVYRPEHISFEELLKVFWENHDPTQGMRQGNDFGTQYRSAVYPTSAVQMEAALRSKEEYQKVLSKHNFGPITTDIREGQVFYYAEDYHQQYLSKNPDGYCGLGGTGVSCPMAIKK", "length": 233 }, "evidence": [ { "id": "MGI:106916", "url": "https://alliancegenome.org/gene/MGI:106916#orthology", "database": "AGR" }, { "id": "HGNC:7377", "url": "https://alliancegenome.org/gene/HGNC:7377#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-344", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-344#orthology", "database": "AGR" }, { "id": "Q5TZ05", "url": "https://omabrowser.org/oma/group/Q5TZ05/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UJ68-1", "protein_name": "Mitochondrial peptide methionine sulfoxide reductase", "gene_name": "MSRA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSATRRACQLLLLHSLFPVPRMGNSASNIVSPQEALPGRKEQTPVAAKHHVNGNRTVEPFPEGTQMAVFGMGCFWGAERKFWVLKGVYSTQVGFAGGYTSNPTYKEVCSEKTGHAEVVRVVYQPEHMSFEELLKVFWENHDPTQGMRQGNDHGTQYRSAIYPTSAKQMEAALSSKENYQKVLSEHGFGPITTDIREGQTFYYAEDYHQQYLSKNPNGYCGLGGTGVSCPVGIKK", "length": 235 }, "evidence": [ { "id": "MGI:106916", "url": "https://alliancegenome.org/gene/MGI:106916#orthology", "database": "AGR" }, { "id": "HGNC:7377", "url": "https://alliancegenome.org/gene/HGNC:7377#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-344", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-344#orthology", "database": "AGR" }, { "id": "Q5TZ05", "url": "https://omabrowser.org/oma/group/Q5TZ05/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ05", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ05", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptide-methionine (S)-S-oxide reductase activity", "id": "GO:0008113", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008113", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ05", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "14217", "name": "", "equation": "L-methionyl-[protein] + [thioredoxin]-disulfide + H2O = L-methionyl-(S)-S-oxide-[protein] + [thioredoxin]-dithiol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1R878-1", "Q5TZ05-1" ], "evidence": [ { "id": "14217", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/14217" } ] }, { "id": "19993", "name": "", "equation": "[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1R878-1", "Q5TZ05-1" ], "evidence": [ { "id": "19993", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19993" } ] }, { "id": "R-DRE-5676940", "name": "MSRA reduces L-methyl-(S)-S-oxide to L-Methionine", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-5676925" ], "output_participant_list": [], "enzyme_list": [ "Q5TZ05-1" ], "evidence": [ { "id": "R-DRE-5676940", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5676940" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-5676925", "participant_name": "L-methionine (S)-S-oxide [cytosol]", "crossref": [ { "id": "49031", "database": "ChEBI", "url": "" }, { "id": "C15999", "database": "COMPOUND", "url": "" }, { "id": "ZINC000001529567", "database": "ZINC", "url": "" }, { "id": "ZINC000003861729", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "F1R878", "gene_name": "msrab", "activity": [ { "ec_number": "1.8.4.11", "activity": "[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol.", "evidence": [ { "id": "F1R878", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R878" } ] }, { "ec_number": "1.8.4.11", "activity": "", "evidence": [ { "id": "F1R878", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R878" } ] } ] }, { "uniprot_ac": "Q5TZ05", "gene_name": "msraa", "activity": [ { "ec_number": "1.8.4.11", "activity": "[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol.", "evidence": [ { "id": "Q5TZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" } ] }, { "ec_number": "1.8.4.11", "activity": "", "evidence": [ { "id": "Q5TZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5TZ05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZ05" }, { "id": "PF01625", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01625" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptide methionine sulphoxide reductase MsrA", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 219, "start_aa": "Val", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.8.4.11", "ec_name": "[thioredoxin]-disulfide + L-methionine + H2O = L-methionine (S)-S-oxide + [thioredoxin]-dithiol.", "evidence": [ { "id": "1.8.4.11", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.8.4.11" }, { "id": "1.8.4.11", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.8.4.11" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5TZD5-1", "uniprot_ac": "Q5TZD5", "uniprot_id": "Q5TZD5_DANRE", "mass": { "chemical_mass": 25005.0, "monoisotopic_mass": 25005.0 }, "refseq": { "ac": "NP_001038266", "name": "rho-related GTP-binding protein RhoJ", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038266" }, "gene_names": [ { "name": "rhoj", "type": "recommended", "evidence": [ { "id": "Q5TZD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ] }, { "name": "rhoj", "type": "synonym", "evidence": [ { "id": "NP_001038266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038266" } ] }, { "name": "si:dkey-100h21.1", "type": "synonym", "evidence": [ { "id": "NP_001038266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038266" }, { "id": "Q5TZD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ] } ], "protein_names": [ { "name": "Rho-related GTP-binding protein RhoJ", "type": "synonym", "evidence": [ { "id": "Q5TZD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5/entry#names_and_taxonomy" } ] }, { "name": "ras homolog gene family, member J", "type": "synonym", "evidence": [ { "id": "NP_001038266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038266" } ] }, { "name": "rho-related GTP-binding protein RhoJ", "type": "synonym", "evidence": [ { "id": "NP_001038266", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038266" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01023233.1, GFIL01032658.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476741, SAMEA4476746 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. On Sep 1, 2006 this sequence version replaced XP_684252.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001038266", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038266" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rhoj", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040724-272", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-272", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000020250", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000020250", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "556371", "url": "https://www.ncbi.nlm.nih.gov/gene/556371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003578", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003578", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556371", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ARMNCKE", "url": "https://omabrowser.org/oma/group/ARMNCKE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5TZD5", "url": "https://www.orthodb.org/?gene=Q5TZD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24072", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24072", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00071", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00071", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-9013409", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013409", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001038266", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038266", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TZD5-1", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040724-272", "url": "https://zfin.org/ZDB-GENE-040724-272", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPTLSSKSRQNALEAAEDGGSNSDPVNTTAKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYIPTVFDHYAVNVTVSGRQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELRSCMPHVPYILIGTQIDLRDDPKTLARLLQMKEKPLTYEQGLKLAREIGAQCYLECSALTQKGLKTVFDEAILTIFSPKKQKRGCAACRCCCALV", "length": 226, "header": "tr|Q5TZD5-1|Q5TZD5_DANRE Isoform 1 of Rho-related GTP-binding protein RhoJ OS=Danio rerio OX=7955 GN=rhoj PE=3 SV=1 CANONICAL=Q5TZD5-1" }, "isoforms": [ { "isoform_ac": "Q5TZD5-1", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5/entry#Q5TZD5-1", "sequence": { "sequence": "MPTLSSKSRQNALEAAEDGGSNSDPVNTTAKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYIPTVFDHYAVNVTVSGRQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELRSCMPHVPYILIGTQIDLRDDPKTLARLLQMKEKPLTYEQGLKLAREIGAQCYLECSALTQKGLKTVFDEAILTIFSPKKQKRGCAACRCCCALV", "length": 226, "header": "tr|Q5TZD5-1|Q5TZD5_DANRE Isoform 1 of Rho-related GTP-binding protein RhoJ OS=Danio rerio OX=7955 GN=rhoj PE=3 SV=1 CANONICAL=Q5TZD5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Genomic annotation and expression analysis of the zebrafish Rho small GTPase family during development and bacterial infection.", "journal": "Genomics", "date": "2005", "authors": "Salas-Vidal Enrique, Meijer Annemarie H, Cheng Xi, Spaink Herman P", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "reference": [ { "type": "PubMed", "id": "15894457", "url": "https://glygen.org/publication/PubMed/15894457" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:556371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556371", "resource": "KEGG Pathway" }, { "id": "R-DRE-9013409", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013409", "resource": "Reactome", "description": "RHOJ GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W6Z9-1", "protein_name": "Ras homolog family member J", "gene_name": "RHOJ", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNCQEGKDRSCGCGHEEKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELRDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKKKRCSECHSCCSII", "length": 213 }, "evidence": [ { "id": "Q5TZD5", "url": "https://omabrowser.org/oma/group/Q5TZD5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Z372-1", "protein_name": "Ras homolog family member J", "gene_name": "RHOJ", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSCKAEGEDCTDGSSNSTKKMLKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGQQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKVCMPNVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKEIGAQCYLECSALTQKGLKTVFDEAILTIFHPKKKKKHCAKCHRCCTIV", "length": 214 }, "evidence": [ { "id": "Q5TZD5", "url": "https://omabrowser.org/oma/group/Q5TZD5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "P19073-1", "protein_name": "Cell division control protein 42", "gene_name": "CDC42", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MQTLKCVVVGDGAVGKTCLLISYTTNQFPADYVPTVFDNYAVTVMIGDEPYTLGLFDTAGQEDYDRLRPLSYPSTDVFLVCFSVISPPSFENVKEKWFPEVHHHCPGVPCLVVGTQIDLRDDKVIIEKLQRQRLRPITSEQGSRLARELKAVKYVECSALTQRGLKNVFDEAIVAALEPPVIKKSKKCAIL", "length": 191 }, "evidence": [ { "id": "MGI:1931551", "url": "https://alliancegenome.org/gene/MGI:1931551#orthology", "database": "AGR" }, { "id": "HGNC:688", "url": "https://alliancegenome.org/gene/HGNC:688#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9ER71-1", "protein_name": "Rho-related GTP-binding protein RhoJ", "gene_name": "Rhoj", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCRERTDSSCGCNGHEENRILKCVVVGDGAVGKTCLLMSYANDAFPEEYVPTVFDHYAVTVTVGGKQHLLGLYDTAGQEDYNQLRPLSYPNTDVFLICFSVVNPASYHNVQEEWVPELKDCMPHVPYVLIGTQIDLRDDPKTLARLLYMKEKPLTYEHGVKLAKAIGAQCYLECSALTQKGLKAVFDEAILTIFHPKKKKKGCLGCHGCCAII", "length": 214 }, "evidence": [ { "id": "MGI:1931551", "url": 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"id": "HGNC:688", "url": "https://alliancegenome.org/gene/HGNC:688#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-272", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-272#orthology", "database": "AGR" }, { "id": "Q5TZD5", "url": "https://omabrowser.org/oma/group/Q5TZD5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SBJ6-1", "protein_name": "Rac-like GTP-binding protein ARAC6", "gene_name": "ARAC6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSASRFIKCVTVGDGAVGKTCLLISYTSNTFPTDYVPTVFDNFSANVVVNGATVNLGLWDTAGQEDYNRLRPLSYRGADVFILAFSLISKASYENVSKKWIPELKHYAPGVPIVLVGTKLDLRDDKQFFIDHPGAVPITTVQGEELKKLIGAPAYIECSSKSQENVKGVFDAAIRVVLQPPKQKKKKNKAQKACSIL", "length": 197 }, "evidence": [ { "id": "Q5TZD5", "url": "https://omabrowser.org/oma/group/Q5TZD5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "pmid": "" }, { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "pmid": "" }, { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "Q5TZD5", "url": "https://www.uniprot.org/uniprotkb/Q5TZD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5TZE2-1", "uniprot_ac": "Q5TZE2", "uniprot_id": "SYN1L_DANRE", "mass": { "chemical_mass": 27809.0, "monoisotopic_mass": 27809.0 }, "refseq": { "ac": "NP_001038246", "name": "synapse differentiation-inducing gene protein 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038246" }, "gene_names": [ { "name": "syndig1l", "type": "recommended", "evidence": [ { "id": "Q5TZE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2" } ] }, { "name": "DSPC1", "type": "synonym", "evidence": [ { "id": "NP_001038246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038246" } ] }, { "name": "si:ch211-146n9.2", "type": "synonym", "evidence": [ { "id": "Q5TZE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2" } ] }, { "name": "si:dkey-263b2.1", "type": "synonym", "evidence": [ { "id": "NP_001038246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038246" }, { "id": "Q5TZE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2" } ] }, { "name": "syndig1l", "type": "synonym", "evidence": [ { "id": "NP_001038246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038246" } ] }, { "name": "tmem90a", "type": "synonym", "evidence": [ { "id": "NP_001038246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038246" } ] } ], "protein_names": [ { "name": "Synapse differentiation-inducing gene protein 1-like", "type": "recommended", "evidence": [ { "id": "Q5TZE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2/entry#names_and_taxonomy" } ] }, { "name": "Capucin", "type": "synonym", "evidence": [ { "id": "Q5TZE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2/entry#names_and_taxonomy" } ] }, { "name": "DSPC1", "type": "synonym", "evidence": [ { "id": "Q5TZE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2/entry#names_and_taxonomy" } ] }, { "name": "Dispanin subfamily C member 1", "type": "synonym", "evidence": [ { "id": "Q5TZE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2/entry#names_and_taxonomy" } ] }, { "name": "Transmembrane protein 90A", "type": "synonym", "evidence": [ { "id": "Q5TZE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2/entry#names_and_taxonomy" } ] }, { "name": "capucin", "type": "synonym", "evidence": [ { "id": "NP_001038246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038246" } ] }, { "name": "dispanin subfamily C member 1", "type": "synonym", "evidence": [ { "id": "NP_001038246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038246" } ] }, { "name": "synapse differentiation-inducing gene protein 1-like", "type": "synonym", "evidence": [ { "id": "NP_001038246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038246" } ] }, { "name": "transmembrane protein 90A", "type": "synonym", "evidence": [ { "id": "NP_001038246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038246" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC171615.1, GFIL01040262.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. On Sep 1, 2006 this sequence version replaced XP_682748.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001038246", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038246" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TZE2", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "syndig1l", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041001-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-116", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5TZE2", "url": "https://alphafold.ebi.ac.uk/entry/Q5TZE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000042390", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000042390", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "555204", "url": "https://www.ncbi.nlm.nih.gov/gene/555204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:555204", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555204", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KMKSQQF", "url": "https://omabrowser.org/oma/group/KMKSQQF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5TZE2", "url": "https://www.orthodb.org/?gene=Q5TZE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14768", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14768", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14768:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14768:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5TZE2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5TZE2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001038246", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038246", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5TZE2", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TZE2-1", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041001-116", "url": "https://zfin.org/ZDB-GENE-041001-116", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MESLSELQNPLLDKNSKHMVMADYGYGGDFHSNQYQENIINYFVTGGGGGGGGGGGGGGVAVTGGNGKAKSQLLDATSLHLAVEAFYKPNFILYKDDVSGKGKDYKNECCETTFMEKKDKEVVVETPSTEDPQAKLLDENDVKIQTVSYEVEEEEYVEYETDCSSDSESEDNFIVIPPRDHLGLAIFSMLCCFWPLGIAAFYFSQGTSKAVTKGDFPLASIASRRALFLAALSITIGTGVYVGVVVALIAYLSKPGHI", "length": 258, "header": "sp|Q5TZE2-1|SYN1L_DANRE Isoform 1 of Synapse differentiation-inducing gene protein 1-like OS=Danio rerio OX=7955 GN=syndig1l PE=3 SV=1 CANONICAL=Q5TZE2-1" }, "isoforms": [ { "isoform_ac": "Q5TZE2-1", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2/entry#Q5TZE2-1", "sequence": { "sequence": "MESLSELQNPLLDKNSKHMVMADYGYGGDFHSNQYQENIINYFVTGGGGGGGGGGGGGGVAVTGGNGKAKSQLLDATSLHLAVEAFYKPNFILYKDDVSGKGKDYKNECCETTFMEKKDKEVVVETPSTEDPQAKLLDENDVKIQTVSYEVEEEEYVEYETDCSSDSESEDNFIVIPPRDHLGLAIFSMLCCFWPLGIAAFYFSQGTSKAVTKGDFPLASIASRRALFLAALSITIGTGVYVGVVVALIAYLSKPGHI", "length": 258, "header": "sp|Q5TZE2-1|SYN1L_DANRE Isoform 1 of Synapse differentiation-inducing gene protein 1-like OS=Danio rerio OX=7955 GN=syndig1l PE=3 SV=1 CANONICAL=Q5TZE2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The dispanins: a novel gene family of ancient origin that contains 14 human members.", "journal": "PLoS ONE", "date": "2012", "authors": "Sallman Almen M, Bringeland N, Fredriksson R, Schioth HB", "evidence": [ { "database": "UniProtKB", "id": "Q5TZE2", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2" } ], "reference": [ { "type": "PubMed", "id": "22363774", "url": "https://glygen.org/publication/PubMed/22363774" } ] }, { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "Q5TZE2", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:555204", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555204", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XSB2-1", "protein_name": "Synapse differentiation inducing 1 like", "gene_name": "SYNDIG1L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MESVRELQDPLLAKANGHLHSSYSYHQHHNQDYPGHHCQGKLYSYIFQNTGGARTHQLLDASSLQLAVEALYGPNFILVKDETALKAKDSKTESCETTFTEGKEVLSDSPDGHEAQGSCLVESDIRIQTVSYEVEEEELQEYESDSSSDSESEDQFLMLPPRDHLGLALFSMLCCFWPLGIAAFYFSQGTSKAVSKGDFHLASSASRRALFLAALSITIGTGVYVGVVVALIAYLSKGGHV", "length": 241 }, "evidence": [ { "id": "Q5TZE2", "url": "https://omabrowser.org/oma/group/Q5TZE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A6NDD5-1", "protein_name": "Synapse differentiation-inducing gene protein 1-like", "gene_name": "SYNDIG1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESLSELQNPLLPRSPAHLHGPYPYPETPPSWSCQEKLYSYLLGGAGPAGAHQLLDPGSLQLAVEAWYRPSCLLGRDKVKEPRAGSCETSFTEDREPQEGPPEQPTGPGQAAENVTIQTVSYGVQEELRDQEDDQEEEESDATSTESESEDNFLTLPPRDHLGLTLFSMLCCFWPLGIAAFYFSQGTSKAISKGDFRLASTTSRRALFLATLAIAVGAGLYVAVVVALAAYMSQNGHG", "length": 238 }, "evidence": [ { "id": "RGD:1589004", "url": "https://alliancegenome.org/gene/RGD:1589004#orthology", "database": "AGR" }, { "id": "MGI:2685107", "url": "https://alliancegenome.org/gene/MGI:2685107#orthology", "database": "AGR" }, { "id": "HGNC:32388", "url": "https://alliancegenome.org/gene/HGNC:32388#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-116#orthology", "database": "AGR" }, { "id": "Q5TZE2", "url": "https://omabrowser.org/oma/group/Q5TZE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4A4K5-1", "protein_name": "Synapse differentiation inducing 1-like", "gene_name": "Syndig1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESMSELQNPLLPRSPTHLHRPYPYPEAPPGWSCQEKLYSYLLGGAGPAQAHQLLDPGSLQLAVEAWYRPSCLLGRDKVKEPKAGSCETSFTEAREPLVGPAEQRSEPGQAEEDVTIHTVSYGVQEELQGQEDSQEEESDGTSTESECEDAFLTLPPRDHLGLTLFSMLCCFWPLGIAAFYFSQGTSKAISKGDFRLASTTSRRALFLAILSIAVGAGLYVAVVVALAAYMSQNGHG", "length": 237 }, "evidence": [ { "id": "RGD:1589004", "url": "https://alliancegenome.org/gene/RGD:1589004#orthology", "database": "AGR" }, { "id": "MGI:2685107", "url": "https://alliancegenome.org/gene/MGI:2685107#orthology", "database": "AGR" }, { "id": "HGNC:32388", "url": "https://alliancegenome.org/gene/HGNC:32388#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-116#orthology", "database": "AGR" }, { "id": "Q5TZE2", "url": "https://omabrowser.org/oma/group/Q5TZE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3IHZ8-1", "protein_name": "Synapse differentiation-inducing gene protein 1-like", "gene_name": "Syndig1l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MESLSELQNPLLPRSPAHLHSPYPYPEAPSSWSCQEKLYNYLLGGAGPAHTHQLLDPGSLQLAVEAWYRPSCLLGKDKIKEPKTGSCETSFTEAREPPVGPAEQGSEPGQTEEDVTIHTVSYGVQEELQGQEDSQEEESDATSTESENEDTFLTLPPRDHLGLTLFSMLCCFWPLGIAAFYFSQGTSKAISKGDFRLATTTSRRALFLATLSIAVGAGLYVAVVVALAAYMSQNGHG", "length": 237 }, "evidence": [ { "id": "Q5TZE2", "url": "https://omabrowser.org/oma/group/Q5TZE2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3USQ7-1", "protein_name": "Synapse differentiation-inducing gene protein 1-like", "gene_name": "Syndig1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESLSELQNPLLPRSPTHLHRPYPYPEAPPGWSCQEQLYSFLLGGAGPARAHQLLDPGSLQLAVEAWYRPSCLLGRDKVKEPKAGSCETSFTEAREPLAGPAEEGSEPGQAAEDVTIHTVSYGVQEELQGQEDSQEEESDGTSSESECEDAFLTLPPRDHLGLTLFSMLCCFWPLGIAAFYFSQGTSKAISKGDFRLASTTSRRALFLATLSIAVGAGLYVAVVVALAAYMSQNGHG", "length": 237 }, "evidence": [ { "id": "RGD:1589004", "url": "https://alliancegenome.org/gene/RGD:1589004#orthology", "database": "AGR" }, { "id": "MGI:2685107", "url": "https://alliancegenome.org/gene/MGI:2685107#orthology", "database": "AGR" }, { "id": "HGNC:32388", "url": "https://alliancegenome.org/gene/HGNC:32388#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-116#orthology", "database": "AGR" }, { "id": "Q5TZE2", "url": "https://omabrowser.org/oma/group/Q5TZE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5TZE2", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5TZE2", "url": "https://www.uniprot.org/uniprotkb/Q5TZE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5TZH2-1", "uniprot_ac": "Q5TZH2", "uniprot_id": "Q5TZH2_DANRE", "mass": { "chemical_mass": 26708.0, "monoisotopic_mass": 26708.0 }, "refseq": { "ac": "NP_998303", "name": "protein lifeguard 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998303" }, "gene_names": [ { "name": "tmbim4", "type": "recommended", "evidence": [ { "id": "Q5TZH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2" } ] }, { "name": "tmbim4", "type": "synonym", "evidence": [ { "id": "NP_998303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998303" } ] }, { "name": "wu:fb34a09", "type": "synonym", "evidence": [ { "id": "NP_998303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998303" }, { "id": "Q5TZH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2" } ] }, { "name": "zgc:64112", "type": "synonym", "evidence": [ { "id": "NP_998303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998303" }, { "id": "Q5TZH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2" } ] } ], "protein_names": [ { "name": "Protein lifeguard 4", "type": "synonym", "evidence": [ { "id": "Q5TZH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2/entry#names_and_taxonomy" } ] }, { "name": "protein lifeguard 4", "type": "synonym", "evidence": [ { "id": "NP_998303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998303" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01040903.1, BC057432.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1, EH442390.1 and EH490666.1. On May 22, 2009 this sequence version replaced NP_998303.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_998303", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998303" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5TZH2", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmbim4", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040426-2152", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2152", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000014361", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000014361", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10429", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10429", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "406412", "url": "https://www.ncbi.nlm.nih.gov/gene/406412", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:406412", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:406412", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FGVMSLY", "url": "https://omabrowser.org/oma/group/FGVMSLY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5TZH2", "url": "https://www.orthodb.org/?gene=Q5TZH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23291", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23291", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23291:SF50", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23291:SF50", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_998303", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998303", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5TZH2", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TZH2-1", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040426-2152", "url": "https://zfin.org/ZDB-GENE-040426-2152", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNQEKHPRSSIEDDFNYGTNVATASVHIRMDFLRKVYTILSLQIIITTAVSALFMLCNPIKNFVHESPSLVLISAIGSLILLLALAFYRHQHPVNLYLLFGFTLLESLSVATAVSFYEYTIVLQAFVLTSAVFLGLTAYTFQSKRDFSKLGASLFAGLWILIIASFLRFFFYNDTMELVFAGAGALLFCGFIIFDTHLLMHKLSPEEHVLASINLYLDIVNLFLYILRILDAMKKH", "length": 236, "header": "tr|Q5TZH2-1|Q5TZH2_DANRE Isoform 1 of Protein lifeguard 4 OS=Danio rerio OX=7955 GN=tmbim4 PE=3 SV=1 CANONICAL=Q5TZH2-1" }, "isoforms": [ { "isoform_ac": "Q5TZH2-1", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2/entry#Q5TZH2-1", "sequence": { "sequence": "MNQEKHPRSSIEDDFNYGTNVATASVHIRMDFLRKVYTILSLQIIITTAVSALFMLCNPIKNFVHESPSLVLISAIGSLILLLALAFYRHQHPVNLYLLFGFTLLESLSVATAVSFYEYTIVLQAFVLTSAVFLGLTAYTFQSKRDFSKLGASLFAGLWILIIASFLRFFFYNDTMELVFAGAGALLFCGFIIFDTHLLMHKLSPEEHVLASINLYLDIVNLFLYILRILDAMKKH", "length": 236, "header": "tr|Q5TZH2-1|Q5TZH2_DANRE Isoform 1 of Protein lifeguard 4 OS=Danio rerio OX=7955 GN=tmbim4 PE=3 SV=1 CANONICAL=Q5TZH2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "Q5TZH2", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Aconitum alkaloids induce cardiotoxicity and apoptosis in embryonic zebrafish by influencing the expression of cardiovascular relative genes.", "journal": "Toxicol. Lett.", "date": "2019", "authors": "Liu Fei, Han Xu, Li Nan, Liu Kun, Kang Weijun", "evidence": [ { "database": "UniProtKB", "id": "Q5TZH2", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2" } ], "reference": [ { "type": "PubMed", "id": "30639578", "url": "https://glygen.org/publication/PubMed/30639578" } ] }, { "title": "tmbim4 protects against triclocarban-induced embryonic toxicity in zebrafish by regulating autophagy and apoptosis.", "journal": "Environ. Pollut.", "date": "2021", "authors": "Hu Zhiyong, He Liting, Wei Jiajing, Su Yufang, Wang Wei, Fan Zunpan, Xu Jia, Zhang Yuan, Wang Yongfeng, Peng Meilin, Zhao Kai, Zhang Huiping, Liu Chunyan", "evidence": [ { "database": "UniProtKB", "id": "Q5TZH2", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2" } ], "reference": [ { "type": "PubMed", "id": "33714789", "url": "https://glygen.org/publication/PubMed/33714789" } ] } ], "pathway": [ { "id": "dre:406412", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:406412", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LRB3-1", "protein_name": "Transmembrane BAX inhibitor motif containing 4", "gene_name": "Tmbim4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADTDPRYPRSSIEDDFNYGSCVASASVHIRMAFLRKVYSILSLQVLLTTVTSALFLYFETLRTFVHDSPALIVVFALGSLGLIFALTLHRHTHPLNLYLLFAFTLSEALTVATVVTFYDGHLVLHAFILTAAVFLGLTAYTLQSKRDFSKFGAGLFACLWILCLAGFLKVFFYSQTVELVLASLGALLFCGFIIYDTHSLMHRLSPEEYVLAAISLYLDIINLFLHLLKFLDAVNKK", "length": 238 }, "evidence": [ { "id": "MGI:1915462", "url": "https://alliancegenome.org/gene/MGI:1915462#orthology", "database": "AGR" }, { "id": "HGNC:24257", "url": "https://alliancegenome.org/gene/HGNC:24257#orthology", "database": "AGR" }, { "id": "Q5TZH2", "url": "https://omabrowser.org/oma/group/Q5TZH2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1C1Z9-1", "protein_name": "Transmembrane BAX inhibitor motif containing 4", "gene_name": "TMBIM4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAEQLYPRSSIEDDFNYGSNVASASVHIRMAFLRKVYSILSIQVLLTTVTSAIFLYSTGVQAFVHERPALLLISVFGCLAISFALALYRHQHPVNLYLLFGFTLLEAFTVAITVSFYDVSIVLQAFILTTAVFLGLTAYTLQSKRDFSKFGAGLFACLWILIFSCFLMVFFHSEIMELVFAAAGALLFCGFIIYDTHLLMHKLSPEEYILAAINLYLDIINLFLNLLRLLEAFNKK", "length": 237 }, "evidence": [ { "id": "Q5TZH2", "url": "https://omabrowser.org/oma/group/Q5TZH2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GY10-1", "protein_name": "Protein lifeguard 4", "gene_name": "Tmbim4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADTDPRYPRSSIEDDFNYGSCVASASVHIRMAFLRKVYSILSLQVLLTTVTSAVFLHFESVRTFVHESPALILVFALGSLGLIFALTLHRHKHPLNLYLLFAFTLLEALTVAVVVTFYDVYLVLQAFILSTAVFLGLTAYTLQSKRDFSKFGAGLFAVLWILCLAGFLKVFFHSETLELVLASVGALLFCGFIIYDTHSLMHRLSPEEYVLAAINLYLDIINLFLHLLRFLEAVNKK", "length": 238 }, "evidence": [ { "id": "Q5TZH2", "url": "https://omabrowser.org/oma/group/Q5TZH2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P48558-1", "protein_name": "Bax inhibitor 1", "gene_name": "BXI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSGPPPPYEEQSSHLYGQPASSQDGNAFIPEDFKYSTVVISCEPIIRQRFMHKVYSLLSCQLLASLSFCYWASVSTSLQNFIMSHIALFYICMVVSLVSCIWLAVSPRPEDYEASVPEPLLTGSSEEPAQEQRRLPWYVLSSYKQKLTLLSIFTLSEAYCLSLVTLAYDKDTVLSALLITTIVVVGVSLTALSERFENVLNSATSIYYWLNWGLWIMIGMGLTALLFGWNTHSSKFNLLYGWLGAILFTAYLFIDTQLIFRKVYPDEEVRCAMMLYLDIVNLFLSILRILANSNDDN", "length": 297 }, "evidence": [ { "id": "MGI:1915462", "url": "https://alliancegenome.org/gene/MGI:1915462#orthology", "database": "AGR" }, { "id": "HGNC:24257", "url": "https://alliancegenome.org/gene/HGNC:24257#orthology", "database": "AGR" }, { "id": "Q5TZH2", "url": "https://omabrowser.org/oma/group/Q5TZH2/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9DA39-1", "protein_name": "Protein lifeguard 4", "gene_name": "Tmbim4", 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{ "database": "UniProtKB", "id": "Q5TZH2", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5TZH2", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum unfolded protein response", "id": "GO:0030968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030968", "evidence": [ { "database": "UniProtKB", "id": "Q5TZH2", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2" } ], "pmid": "" }, { "name": "regulation of autophagic cell death", "id": "GO:1904092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1904092", "evidence": [ { "database": "UniProtKB", "id": "Q5TZH2", "url": "https://www.uniprot.org/uniprotkb/Q5TZH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 173, "end_pos": 175 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"name": "ppp1r21", "type": "recommended", "evidence": [ { "id": "Q5U3A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8" } ] }, { "name": "Fy-2", "type": "synonym", "evidence": [ { "id": "Q5U3A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8" } ] }, { "name": "ccdc128", "type": "synonym", "evidence": [ { "id": "Q5U3A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8" } ] }, { "name": "klraq1", "type": "synonym", "evidence": [ { "id": "Q5U3A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8" } ] }, { "name": "zgc:92087", "type": "synonym", "evidence": [ { "id": "Q5U3A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 21", "type": "recommended", "evidence": [ { "id": "Q5U3A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 128", "type": "synonym", "evidence": [ { "id": "Q5U3A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8/entry#names_and_taxonomy" } ] }, { "name": "Ferry endosomal RAB5 effector complex subunit 2", "type": "synonym", "evidence": [ { "id": "Q5U3A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8/entry#names_and_taxonomy" } ] }, { "name": "Fy-2", "type": "synonym", "evidence": [ { "id": "Q5U3A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8/entry#names_and_taxonomy" } ] }, { "name": "KLRAQ motif-containing protein 1", "type": "synonym", "evidence": [ { "id": "Q5U3A8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "Component of the FERRY complex (Five-subunit Endosomal Rab5 and RNA/ribosome intermediary). The FERRY complex directly interacts with mRNAs and RAB5A, and functions as a RAB5A effector involved in the localization and the distribution of specific mRNAs most likely by mediating their endosomal transport. The complex recruits mRNAs and ribosomes to early endosomes through direct mRNA-interaction (By similarity). Putative regulator of protein phosphatase 1 (PP1) activity. May play a role in the endosomal sorting process or in endosome maturation pathway (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5U3A8", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8#function" }, { "database": "UniProtKB", "id": "Q6ZMI0", "url": "https://www.uniprot.org/uniprotkb/Q6ZMI0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U3A8", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ppp1r21", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041114-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-8", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5U3A8", "url": "https://alphafold.ebi.ac.uk/entry/Q5U3A8", "database": "AlphaFoldDB", "categories": [] }, { "id": "492333", "url": "https://www.ncbi.nlm.nih.gov/gene/492333", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019343", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019343", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019348", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019348", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:492333", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492333", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5U3A8", "url": "https://www.orthodb.org/?gene=Q5U3A8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21448", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21448", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21448:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21448:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21636", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21636", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5U3A8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5U3A8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0AC58H0W3", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0W3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0W3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0W6", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0W6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0W6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0W6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0Y6", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5U3A8", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5U3A8-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041114-8", "url": "https://zfin.org/ZDB-GENE-041114-8", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTDLQSKYSKLAQEYSKLRAQNQVLKKAVVDEQSSCNSLKDELKQKEQSLRRVEQEMDSLSFRNQQLMKRVELLQEELLLSESKSKKSRSKGDSPSQVSLQAQSVFDEDLHKKIQENERLHIQWLEAQEQHQQQEAQLSSRLQQLQEEAQEHQAQLEELSCRHAHTIHTLQEDKATLEVKLQTLEREARDCRVRTEECQQQLRKYQSEVSSQLKHSSSVIQEKVPFNDTQLSDYNSLNVPAHNRRHQLRAREVAAQALVFLQNLVSALLNFHSYSEQRVQIYPRDSSIETISAVNQKFSQYLHENASYLRQLEEDLLQLHQSITEDLPAATQKFCTTNECLLSSLASLTSSSGKMATFFSNSLDFLTSCAGYSPSGALLKPLQADSVMQSKRRAAAYISSVRQARAESVPYGEALANRHILTSSTESREGLMQQVLQSQQKISRLEQEKEHWLLEAQLAQVRLQKESARIAQLEAQVCVSAPQSQLCASAAESPVCVSAAESQVCVSAAETPSEPALADAPEPLQDTSVVGVLSIRSCSESSADQDSREQLIKTHYMSRVSELTTQLQICDSKAVHFHAECRAVAKRLAMAERSRDTLGEELKLANQNITRLQDELSTTKRSYEDQLSMMSDHLCSMNETLSQQRETIDTLKLSAKGNAKKNKSR", "length": 665, "header": "sp|Q5U3A8-1|PPR21_DANRE Isoform 1 of Protein phosphatase 1 regulatory subunit 21 OS=Danio rerio OX=7955 GN=ppp1r21 PE=2 SV=1 CANONICAL=Q5U3A8-1" }, "isoforms": [ { "isoform_ac": "A0AC58H0W3-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8/entry#A0AC58H0W3-1", "sequence": { "sequence": "MTDLQSKYSKLAQEYSKLRAQNQVLKKAVVDEQSSCNSLKDELKQKEQSLRRVEQEMDSLSFRNQQLMKRVELLQEELLLSESKSKKSRSKGDSPSQVSLQAQSVFDEDLHKKIQENERLHIQWLEAQEQHQQQEAQLSSRLQQLQEEAQEHQAQLEELSCRHAHTIHTLQEDKATLEVKLQTLEREARDCRVRTEECQQQLRKYQSEVSSQLKHSSSVIQEKVPFNDTQLSDYNSLNVPAHNRRHQLRAREVAAQALVFLQNLVSALLNFHSYSEQRVQIYPRDSSIETISAVNQKFSQYLHENASYLRQLEEDLLQLHQSITEDAITALETLEKLQDFSSSFSAYSSFLQKILPYQLKSLEEECESPLCTSALISKNRQLQTDMQKLTAAFHKLRAYVALLALPSVGSGVVCQSSANSVFTQISVCLHGLHDCSSELWKHYSQKASLEQDLPAATQKFCTTNECLLSSLASLTSSSGKMATFFSNSLDFLTSCAGYSPSGALLKPLQADSVMQSKRRAAAYISSVRQARAESVPYGEALANRHILTSSTESREGLMQQVLQSQQKISRLEQEKEHWLLEAQLAQVRLQKESARIAQLEAQVCVSAPQSQLCASAAESPVCVSAAESQVCVSAAETPSEPALADAPEPLQDTSVVGVLSIRSCSESSADQDSREQLIKTHYMSRVSELTTQLQICDSKAVHFHAECRAVAKRLAMAERSRDTLGEELKLANQNITRLQDELSTTKRSYEDQLSMMSDHLCSMNETLSQQRETIDTLKLSAKGNAKKNKSR", "length": 791, "header": "tr|A0AC58H0W3-1|A0AC58H0W3_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 21 OS=Danio rerio OX=7955 GN=ppp1r21 PE=1 SV=1 CANONICAL=Q5U3A8-1" }, "locus": {} }, { "isoform_ac": "A0AC58H0W6-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8/entry#A0AC58H0W6-1", "sequence": { "sequence": "MTDLQSKYSKLAQEYSKLRAQNQVLKKAVVDEQSSCNSLKDELKQKEQSLRRVEQEMDSLSFRNQQLMKRVELLQEELLLSESKSKKSRSKGDSPSQVSLQAQSVFDEDLHKKIQENERLHIQWLEAQEQHQQQEAQLSSRLQQLQEEAQEHQAQLEELSCRHAHTIHTLQEDKATLEVKLQTLEREARDCRVRTEECQQQLRKYQSEVSSQLKHSSSVIQEKVPFNDTQLSDYNSLNVPAHNRRHQLRAREVAAQALVFLQNLVSALLNFHSYSEQRVQIYPRDSSIETISAVNQKFSQYLHENASYLRQLEEDLLQLHQSITEDAITALETLEKLQDFSSSFSAYSSFLQKILPYQLKSLEEECESPLCTSALISKNRQLQTDMQKLTAAFHKLRAYVALLALPSVGSGVVCQSSANSVFTQISVCLHGLHDCSSELWKHYSQKASLEQDLPAATQKFCTTNECLLSSLASLTSSSGKMATFFSNSLDFLTSCAGYSPSGALLKPLQADSVMQSKRRAAAYISSVRQARAESVPYGEALANRHILTSSTESREGLMQQVLQSQQKISRLEQEKEHWLLEAQLAQVRLQKESARIAQLEAQVCVSAPQSQLCASAAESPVCVSAAESQVCVSAAETPSEPALADAPEPLQDTSVSADQDSREQLIKTHYMSRVSELTTQLQICDSKAVHFHAECRAVAKRLAMAERSRDTLGEELKLANQNITRLQDELSTTKRSYEDQLSMMSDHLCSMNETLSQQRETIDTLKLSAKGNAKKNKSR", "length": 779, "header": "tr|A0AC58H0W6-1|A0AC58H0W6_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 21 OS=Danio rerio OX=7955 GN=ppp1r21 PE=1 SV=1 CANONICAL=Q5U3A8-1" }, "locus": {} }, { "isoform_ac": "A0AC58H0Y6-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8/entry#A0AC58H0Y6-1", "sequence": { "sequence": "MCVCVCVCVCVCVRTQSKGDSPSQVSLQAQSVFDEDLHKKIQENERLHIQWLEAQEQHQQQEAQLSSRLQQLQEEAQEHQAQLEELSCRHAHTIHTLQEDKATLEVKLQTLEREARDCRVRTEECQQQLRKYQSEVSSQLKHSSSVIQEKVPFNDTQLSDYNSLNVPAHNRRHQLRAREVAAQALVFLQNLVSALLNFHSYSEQRVQIYPRDSSIETISAVNQKFSQYLHENASYLRQLEEDLLQLHQSITEDAITALETLEKLQDFSSSFSAYSSFLQKILPYQLKSLEEECESPLCTSALISKNRQLQTDMQKLTAAFHKLRAYVALLALPSVGSGVVCQSSANSVFTQISVCLHGLHDCSSELWKHYSQKASLEQDLPAATQKFCTTNECLLSSLASLTSSSGKMATFFSNSLDFLTSCAGYSPSGALLKPLQADSVMQSKRRAAAYISSVRQARAESVPYGEALANRHILTSSTESREGLMQQVLQSQQKISRLEQEKEHWLLEAQLAQVRLQKESARIAQLEAQVCVSAPQSQLCASAAESPVCVSAAESQVCVSAAETPSEPALADAPEPLQDTSVVGVLSIRSCSESSADQDSREQLIKTHYMSRVSELTTQLQICDSKAVHFHAECRAVAKRLAMAERSRDTLGEELKLANQNITRLQDELSTTKRSYEDQLSMMSDHLCSMNETLSQQRETIDTLKLSAKGNAKKNKSR", "length": 718, "header": "tr|A0AC58H0Y6-1|A0AC58H0Y6_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 21 isoform X3 OS=Danio rerio OX=7955 GN=ppp1r21 PE=1 SV=1 CANONICAL=Q5U3A8-1" }, "locus": {} }, { "isoform_ac": "Q5U3A8-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8/entry#Q5U3A8-1", "sequence": { "sequence": "MTDLQSKYSKLAQEYSKLRAQNQVLKKAVVDEQSSCNSLKDELKQKEQSLRRVEQEMDSLSFRNQQLMKRVELLQEELLLSESKSKKSRSKGDSPSQVSLQAQSVFDEDLHKKIQENERLHIQWLEAQEQHQQQEAQLSSRLQQLQEEAQEHQAQLEELSCRHAHTIHTLQEDKATLEVKLQTLEREARDCRVRTEECQQQLRKYQSEVSSQLKHSSSVIQEKVPFNDTQLSDYNSLNVPAHNRRHQLRAREVAAQALVFLQNLVSALLNFHSYSEQRVQIYPRDSSIETISAVNQKFSQYLHENASYLRQLEEDLLQLHQSITEDLPAATQKFCTTNECLLSSLASLTSSSGKMATFFSNSLDFLTSCAGYSPSGALLKPLQADSVMQSKRRAAAYISSVRQARAESVPYGEALANRHILTSSTESREGLMQQVLQSQQKISRLEQEKEHWLLEAQLAQVRLQKESARIAQLEAQVCVSAPQSQLCASAAESPVCVSAAESQVCVSAAETPSEPALADAPEPLQDTSVVGVLSIRSCSESSADQDSREQLIKTHYMSRVSELTTQLQICDSKAVHFHAECRAVAKRLAMAERSRDTLGEELKLANQNITRLQDELSTTKRSYEDQLSMMSDHLCSMNETLSQQRETIDTLKLSAKGNAKKNKSR", "length": 665, "header": "sp|Q5U3A8-1|PPR21_DANRE Isoform 1 of Protein phosphatase 1 regulatory subunit 21 OS=Danio rerio OX=7955 GN=ppp1r21 PE=2 SV=1 CANONICAL=Q5U3A8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "Q5U3A8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5U3A8" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q5U3A8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q5U3A8" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:492333", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492333", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LYZ8-1", "protein_name": "Protein phosphatase 1 regulatory subunit 21", "gene_name": "Ppp1r21", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQASSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEHHKLVEAELRSRLATLETEAAQHQAVIDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKNLHEDLSGRLEESLSIINEKVPFNDTKCNQYNALNVPLHNRRHQLKMRDLAGQALAFVQDLVPALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQHLHENAAYVRPLEEGMLHLFESITEDTVTVLETTVKLKVFSDHLTSYVRFLRKILPYQLKSLEEECESSLCTPALRARNLELSQDMKRMTAVFEKLQTYITLLALPSTEPDGLLRTNYTSVLTNVGAALHGFHDVMKDISKHYSQKASIEHELPTATQKLVTTNDCILSSAVALTNGAGKIASFFSNNMDYFIASLSYGPKTASGFISPLSAECMLQYKKKAAAYMKSLRKPLAESVPYEEALANRRVLLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADRLRSTSSAQLLGLAQENATVSIASGQEEAAAKALTEPVQSTSLIGILTRTPESEAPDIESREDLIKSHYMARIAELTSQLQLADSKSVHFYAECRALSKRLALAEKSKETLTEEMRLASQNVSRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQRDEIDTLKMSSKGNAKKNRSR", "length": 780 }, "evidence": [ { "id": "RGD:1565310", "url": "https://alliancegenome.org/gene/RGD:1565310#orthology", "database": "AGR" }, { "id": "MGI:1921075", "url": "https://alliancegenome.org/gene/MGI:1921075#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-8#orthology", "database": "AGR" }, { "id": "HGNC:30595", "url": "https://alliancegenome.org/gene/HGNC:30595#orthology", "database": "AGR" }, { "id": "FB:FBgn0039204", "url": "https://alliancegenome.org/gene/FB:FBgn0039204#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TDD9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 21", "gene_name": "Ppp1r21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQASSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEHHRHVEAELRSRLATLETEAAQHQAVIDGLTRKYMETIEKLQSDKAKLEVKSQTLEKEAKECRLRTEECQLQLKNLHEDLSGRLEESLSIINEKVPFNDTKCHLYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVPALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKMFSDHLTSYVRFLRKILPYQLKSLEEECESSLCTPALRARNLELSQDMKTMTAVFEKLQTYVTLLALPSTEPDGLLRTNYTSVLTNVGAALHGFHDVMKDISKHYSQKASIEHEIPTATQKLVTTNDCILSSAVTLTNGAGKIASFFGNNVDYFIASLSYGPKTASGFISPLSAECMLQYKKKAAAYMKSLRTPLAESVPYGEAVANRRVLLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADRLRGTTSAQLPGLAQENATVPIASSQEEAAAKVLTEPVQSTSLVGMLTRTPDSEAPDVESREDLIKSHYMARIAELTSQLQLADSKSVHFYAECRALSKRLALAEKSKETLTEEMRLASQNISRLQDELMTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMASKGNSKKTRNR", "length": 780 }, "evidence": [ { "id": "RGD:1565310", "url": "https://alliancegenome.org/gene/RGD:1565310#orthology", "database": "AGR" }, { "id": "MGI:1921075", "url": "https://alliancegenome.org/gene/MGI:1921075#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-8#orthology", "database": "AGR" }, { "id": "HGNC:30595", "url": "https://alliancegenome.org/gene/HGNC:30595#orthology", "database": "AGR" }, { "id": "FB:FBgn0039204", "url": "https://alliancegenome.org/gene/FB:FBgn0039204#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMI0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 21", "gene_name": "PPP1R21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASAELQGKYQKLAQEYSKLRAQNQVLKKGVVDEQANSAALKEQLKMKDQSLRKLQQEMDSLTFRNLQLAKRVELLQDELALSEPRGKKNKKSGESSSQLSQEQKSVFDEDLQKKIEENERLHIQFFEADEQHKHVEAELRSRLATLETEAAQHQAVVDGLTRKYMETIEKLQNDKAKLEVKSQTLEKEAKECRLRTEECQLQLKTLHEDLSGRLEESLSIINEKVPFNDTKYSQYNALNVPLHNRRHQLKMRDIAGQALAFVQDLVTALLNFHTYTEQRIQIFPVDSAIDTISPLNQKFSQYLHENASYVRPLEEGMLHLFESITEDTVTVLETTVKLKTFSEHLTSYICFLRKILPYQLKSLEEECESSLCTSALRARNLELSQDMKKMTAVFEKLQTYIALLALPSTEPDGLLRTNYSSVLTNVGAALHGFHDVMKDISKHYSQKAAIEHELPTATQKLITTNDCILSSVVALTNGAGKIASFFSNNLDYFIASLSYGPKAASGFISPLSAECMLQYKKKAAAYMKSLRKPLLESVPYEEALANRRILLSSTESREGLAQQVQQSLEKISKLEQEKEHWMLEAQLAKIKLEKENQRIADKLKNTGSAQLVGLAQENAAVSNTAGQDEATAKAVLEPIQSTSLIGTLTRTSDSEVPDVESREDLIKNHYMARIVELTSQLQLADSKSVHFYAECRALSKRLALAEKSKEALTEEMKLASQNISRLQDELTTTKRSYEDQLSMMSDHLCSMNETLSKQREEIDTLKMSSKGNSKKNKSR", "length": 780 }, "evidence": [ { "id": "RGD:1565310", "url": "https://alliancegenome.org/gene/RGD:1565310#orthology", "database": "AGR" }, { "id": "MGI:1921075", "url": "https://alliancegenome.org/gene/MGI:1921075#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-8#orthology", "database": "AGR" }, { "id": "HGNC:30595", "url": "https://alliancegenome.org/gene/HGNC:30595#orthology", "database": "AGR" }, { "id": "FB:FBgn0039204", "url": "https://alliancegenome.org/gene/FB:FBgn0039204#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VC66-1", "protein_name": "Protein phosphatase 1 regulatory subunit 21 N-terminal domain-containing protein", "gene_name": "Dmel\\CG6607", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAEKSLAMDGTVPEAKYQKLATEYSKLRAQATVLKKAVLEEQSKEASLREQLQQYATSLRRTEQEVDSLGFRNKQLESRVSQLQQEISVHEQPKKKDKDSGGRRGVQSNSRPDADPSLDAAQEALIFEELQKKIMENAQLTSLIDDKQRDLLLHTERIASLEQKLEKRIGDQNELEKRLRKEVETLQHRNSELETKLVDAASMLGSEDALSATGSDTTPLHNLQQQSNSNQLTSEDRIALLEKEAAHWRAQFEVAKLHQAFVSNPSKDLSTCSCSTAAAGVTVRPAESEAKGSQRARDSLQDPPEPPTKEQLIYSVFSKKFEDLMRLKVQAESKLRSYELEVQHLQNCLENATHELKAKDDQLASLGGALQMLEEELTTTRINYEEQISVLTEQVISLSDQLAACK", "length": 406 }, "evidence": [ { "id": "RGD:1565310", "url": "https://alliancegenome.org/gene/RGD:1565310#orthology", "database": "AGR" }, { "id": "MGI:1921075", "url": "https://alliancegenome.org/gene/MGI:1921075#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-8#orthology", "database": "AGR" }, { "id": "HGNC:30595", "url": "https://alliancegenome.org/gene/HGNC:30595#orthology", "database": "AGR" }, { "id": "FB:FBgn0039204", "url": "https://alliancegenome.org/gene/FB:FBgn0039204#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5U3A8", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "Q5U3A8", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5U3A8", "url": "https://www.uniprot.org/uniprotkb/Q5U3A8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 608, "end_pos": 610, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 662, "end_pos": 664, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 227, "end_pos": 229 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 608, "end_pos": 610 }, { "start_pos": 638, "end_pos": 640 }, { "start_pos": 662, "end_pos": 664 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5U3G4-1", "uniprot_ac": "Q5U3G4", "uniprot_id": "RDM1_DANRE", "mass": { "chemical_mass": 31526.0, "monoisotopic_mass": 31526.0 }, "refseq": { "ac": "NP_001007334", "name": "RAD52 motif-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007334" }, "gene_names": [ { "name": "rdm1", "type": "recommended", "evidence": [ { "id": "Q5U3G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4" } ] }, { "name": "rdm1", "type": "synonym", "evidence": [ { "id": "NP_001007334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007334" } ] }, { "name": "zgc:103564", "type": "synonym", "evidence": [ { "id": "NP_001007334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007334" }, { "id": "Q5U3G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4" } ] } ], "protein_names": [ { "name": "RAD52 motif-containing protein 1", "type": "recommended", "evidence": [ { "id": "Q5U3G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4/entry#names_and_taxonomy" } ] }, { "name": "RAD52 motif-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001007334", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007334" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC085554.1, EH546871.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476744, SAMEA4476760 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085554.1. On Jul 6, 2005 this sequence version replaced XP_693258.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007334", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007334" } ] }, { "annotation": "May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G4", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U3G4", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rdm1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041114-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-14", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5U3G4", "url": "https://alphafold.ebi.ac.uk/entry/Q5U3G4", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd12364", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12364", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "492461", "url": "https://www.ncbi.nlm.nih.gov/gene/492461", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:492461", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492461", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5U3G4", "url": "https://www.orthodb.org/?gene=Q5U3G4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31164", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31164", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31164:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31164:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5U3G4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5U3G4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007334", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007334", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5U3G4", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5U3G4-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041114-14", "url": "https://zfin.org/ZDB-GENE-041114-14", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDIEVDIIEFKVPLENNKTIFIWDIQPTFTEAYIYESLWSVYSAFGDLYLLKVCPNATVAEPGFYALVKFYSSAQASKAQRATDKQCLFQSSPLKVRLSTKQNLSFYSSKPLCLSKCHNLANHYLGFGGWTTRIVTLKDLSNCVDAGCQEETGDQGVLLKYGCIMELSFPHHGMSCQGVGVAEEVLDSDQDPEEKLRKRGALMKRAKDKAMEVAFEKVLLLILGNGKVAIEIKIDPDEIVPEENSERVIKVNDISWTHIESADSNAEEDFLWDLTEDLPY", "length": 280, "header": "sp|Q5U3G4-1|RDM1_DANRE Isoform 1 of RAD52 motif-containing protein 1 OS=Danio rerio OX=7955 GN=rdm1 PE=2 SV=1 CANONICAL=Q5U3G4-1" }, "isoforms": [ { "isoform_ac": "Q5U3G4-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4/entry#Q5U3G4-1", "sequence": { "sequence": "MDIEVDIIEFKVPLENNKTIFIWDIQPTFTEAYIYESLWSVYSAFGDLYLLKVCPNATVAEPGFYALVKFYSSAQASKAQRATDKQCLFQSSPLKVRLSTKQNLSFYSSKPLCLSKCHNLANHYLGFGGWTTRIVTLKDLSNCVDAGCQEETGDQGVLLKYGCIMELSFPHHGMSCQGVGVAEEVLDSDQDPEEKLRKRGALMKRAKDKAMEVAFEKVLLLILGNGKVAIEIKIDPDEIVPEENSERVIKVNDISWTHIESADSNAEEDFLWDLTEDLPY", "length": 280, "header": "sp|Q5U3G4-1|RDM1_DANRE Isoform 1 of RAD52 motif-containing protein 1 OS=Danio rerio OX=7955 GN=rdm1 PE=2 SV=1 CANONICAL=Q5U3G4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:492461", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492461", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZZZ4-1", "protein_name": "RAD52 motif-containing protein 1", "gene_name": "Rdm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAELISFVVPTQSDKVLLVWELSAGPPAEALSVRVLAEGEGAGITGAQEPRAPVEGGAQRTGSLRGTLSHRRLSGPKMFSQFGLLYSVRVFPNAAVAGPGFYAIVKFYSSRDAQRAQKACDGKPLFQTSPVKVRLGTRHKALQHQAFALNSSRCQELANYYFGFNGWSKRIVKLQELSGLEDAALAVPMQKRNPQFFCAVEVVLPAYGCTSPGVGISEEPLPQLEEGQPSFLTKRKTAQKLAFQAALSDAFQKLTIVVLESGRIAVEYRPTEEDLDARSEEELQNLIQVGCFPSSQSSQREEECLSDFSLEEEDLKLCGLH", "length": 321 }, "evidence": [ { "id": "RGD:1310432", "url": "https://alliancegenome.org/gene/RGD:1310432#orthology", "database": "AGR" }, { "id": "MGI:1913849", "url": "https://alliancegenome.org/gene/MGI:1913849#orthology", "database": "AGR" }, { "id": "HGNC:19950", "url": "https://alliancegenome.org/gene/HGNC:19950#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-14#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NG50-1", "protein_name": "RAD52 motif-containing protein 1", "gene_name": "RDM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELVPFAVPIESDKTLLVWELSSGPTAEALHHSLFTAFSQFGLLYSVRVFPNAAVAHPGFYAVIKFYSARAAHRAQKACDRKQLFQKSPVKVRLGTRHKAVQHQALALNSSKCQELANYYFGFNGCSKRIIKLQELSDLEERENEDSMVPLPKQSLKFFCALEVVLPSCDCRSPGIGLVEEPMDKVEEGPLSFLMKRKTAQKLAIQKALSDAFQKLLIVVLESGKIAVEYRPSEDIVGVRCEEELHGLIQVPCSPWKQYGQEEEGYLSDFSLEEEEFRLPELD", "length": 284 }, "evidence": [ { "id": "RGD:1310432", "url": "https://alliancegenome.org/gene/RGD:1310432#orthology", "database": "AGR" }, { "id": "MGI:1913849", "url": "https://alliancegenome.org/gene/MGI:1913849#orthology", "database": "AGR" }, { "id": "HGNC:19950", "url": "https://alliancegenome.org/gene/HGNC:19950#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-14#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQK3-1", "protein_name": "RAD52 motif-containing protein 1", "gene_name": "Rdm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELISFVVPTQSDKVLLVWDLSTGPPAEALSHSLFTVFSQFGLLYSVRVFPNAAVARPGFYAIIKFYSSRDAQRAQKACDGKPLFQTSPVKVRLGTRHKALQHQAFALNSSRCQELANYYFGFSGWSKRIIKLQELSGLEDAALAVPMQKGSPQFLCAVEVVLPPYGCRSPGVGISEEPLRQLEEGQSSFLMKRKTAQKLAFQAAVSDAFQKLTIVVLESGRIAVEYRPTAEDLDARSEEELQNLIQVSCSSWSQSSQREEECLSDFSLEEEDLKLCDPH", "length": 281 }, "evidence": [ { "id": "RGD:1310432", "url": "https://alliancegenome.org/gene/RGD:1310432#orthology", "database": "AGR" }, { "id": "MGI:1913849", "url": "https://alliancegenome.org/gene/MGI:1913849#orthology", "database": "AGR" }, { "id": "HGNC:19950", "url": "https://alliancegenome.org/gene/HGNC:19950#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-14#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G4", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4" } ], "pmid": "" }, { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G4", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G4", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5U3G4", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5U3G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3G4" }, { "id": "PRU00176", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00176" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000255", "start_pos": 18, "end_pos": 101, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 17, "end_pos": 19 }, { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q5U3H3-1", "uniprot_ac": "Q5U3H3", "uniprot_id": "GL8D1_DANRE", "mass": { "chemical_mass": 41353.0, "monoisotopic_mass": 41353.0 }, "refseq": { "ac": "NP_001007339", "name": "glycosyltransferase 8 domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007339" }, "gene_names": [ { "name": "glt8d1", "type": "recommended", "evidence": [ { "id": "Q5U3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3" } ] }, { "name": "glt8d1", "type": "synonym", "evidence": [ { "id": "NP_001007339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007339" } ] }, { "name": "wu:fc60b12", "type": "synonym", "evidence": [ { "id": "NP_001007339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007339" } ] }, { "name": "zgc:103525", "type": "synonym", "evidence": [ { "id": "NP_001007339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007339" }, { "id": "Q5U3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3" } ] } ], "protein_names": [ { "name": "Glycosyltransferase 8 domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "Q5U3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3/entry#names_and_taxonomy" } ] }, { "name": "2.4.1.-", "type": "synonym", "evidence": [ { "id": "Q5U3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3/entry#names_and_taxonomy" } ] }, { "name": "glycosyltransferase 8 domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001007339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007339" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC085543.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085543.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007339" } ] }, { "annotation": "In vitro, catalyzes the transfer of a galactose residue from UDP-galactose onto GalNAc and GlcNAc structures.", "evidence": [ { "database": "UniProtKB", "id": "Q5U3H3", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3#function" }, { "database": "UniProtKB", "id": "Q68CQ7", "url": "https://www.uniprot.org/uniprotkb/Q68CQ7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U3H3", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "glt8d1", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041114-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-23", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5U3H3", "url": "https://alphafold.ebi.ac.uk/entry/Q5U3H3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06429", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06429", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "492466", "url": "https://www.ncbi.nlm.nih.gov/gene/492466", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:492466", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492466", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5U3H3", "url": "https://www.orthodb.org/?gene=Q5U3H3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13778", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13778", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13778:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13778:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5U3H3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5U3H3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5U3H3", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5U3H3-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041114-23", "url": "https://zfin.org/ZDB-GENE-041114-23", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTVRRVNVVILVLLVVAFLIVLHRNLLNLNDFLNQETSDTVPGMILPFETDFLLGRKAMRSGEEIPVLITAPEERLGAAVTAMNSIYRNSKANVVFNIVTLNESVVHLSTWLSKTDLKHKIIVFDPSILLGKIPTDAQKMETVRPLTFARFYMPAFLPDAEKAIYLDDDVIVQGDIRELFNTSLKSGHVAAFSEDCDSASSKGIVRGAGNQNSYIGYLDFKKEAIKKLGMRANTCSFNPGVFVANLTEWKQQNVTSQLEFWMERNAKEDLYSKTLADCMTTPPMLIVFYKHHSNIDPMWNVRHLGATGAGNRYSAQFVKAAKLLHWNGHYKPWGRTSSFSDIWDKWYIPDPTGKFHPIRKHVEEK", "length": 365, "header": "sp|Q5U3H3-1|GL8D1_DANRE Isoform 1 of Glycosyltransferase 8 domain-containing protein 1 OS=Danio rerio OX=7955 GN=glt8d1 PE=2 SV=1 CANONICAL=Q5U3H3-1" }, "isoforms": [ { "isoform_ac": "Q5U3H3-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3/entry#Q5U3H3-1", "sequence": { "sequence": "MTVRRVNVVILVLLVVAFLIVLHRNLLNLNDFLNQETSDTVPGMILPFETDFLLGRKAMRSGEEIPVLITAPEERLGAAVTAMNSIYRNSKANVVFNIVTLNESVVHLSTWLSKTDLKHKIIVFDPSILLGKIPTDAQKMETVRPLTFARFYMPAFLPDAEKAIYLDDDVIVQGDIRELFNTSLKSGHVAAFSEDCDSASSKGIVRGAGNQNSYIGYLDFKKEAIKKLGMRANTCSFNPGVFVANLTEWKQQNVTSQLEFWMERNAKEDLYSKTLADCMTTPPMLIVFYKHHSNIDPMWNVRHLGATGAGNRYSAQFVKAAKLLHWNGHYKPWGRTSSFSDIWDKWYIPDPTGKFHPIRKHVEEK", "length": 365, "header": "sp|Q5U3H3-1|GL8D1_DANRE Isoform 1 of Glycosyltransferase 8 domain-containing protein 1 OS=Danio rerio OX=7955 GN=glt8d1 PE=2 SV=1 CANONICAL=Q5U3H3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 102, "start_aa": "Asn", "end_pos": 102, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn102", "evidence": [ { "id": "Q5U3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 181, "start_aa": "Asn", "end_pos": 181, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn181", "evidence": [ { "id": "Q5U3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 245, "start_aa": "Asn", "end_pos": 245, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn245", "evidence": [ { "id": "Q5U3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3#ptm_processing" } ] }, { "glytoucan_ac": "", "type": "N-linked", "subtype": "", "prediction_tool_list": [], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "N", "relation": "attached", "comment": "N-linked (GlcNAc...) asparagine", "icn3d_view": {}, "start_pos": 253, "start_aa": "Asn", "end_pos": 253, "end_aa": "Asn", "residue": "Asn", "site_lbl": "Asn253", "evidence": [ { "id": "Q5U3H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3H3#ptm_processing" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycosyltransferase-activity", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:492466", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492466", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q68CQ7-1", "protein_name": "Glycosyltransferase 8 domain-containing protein 1", "gene_name": "GLT8D1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFRKVNIIILVLAVALFLLVLHHNFLSLSSLLRNEVTDSGIVGPQPIDFVPNALRHAVDGRQEEIPVVIAASEDRLGGAIAAINSIQHNTRSNVIFYIVTLNNTADHLRSWLNSDSLKSIRYKIVNFDPKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTALKPGHAAAFSEDCDSASTKVVIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNITNQLEKWMKLNVEEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSAGKRYSPQFVKAAKLLHWNGHLKPWGRTASYTDVWEKWYIPDPTGKFNLIRRYTEISNIK", "length": 371 }, "evidence": [ { "id": "HGNC:24870", "url": "https://alliancegenome.org/gene/HGNC:24870#orthology", "database": "AGR" }, { "id": "MGI:1923735", "url": "https://alliancegenome.org/gene/MGI:1923735#orthology", "database": "AGR" }, { "id": "RGD:1359293", "url": "https://alliancegenome.org/gene/RGD:1359293#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-23#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AYF6-1", "protein_name": "Glycosyltransferase 8 domain-containing protein 1", "gene_name": "Glt8d1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFRKVTIIIWALAVILFLLALHHNFLSLSSLLRNDVSDSGIVGLQPIDFTANFHQHPVNERQEEIPVVIAASEDRLGGTIAAINSIHQNTRSNVIFYIVTFNRTADHLRSWLNSGSLKSIRYKIVNFDTKLLEGKVKEDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTPLKPGHAAAFSEDCDSASTKVMIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNVTNQLEKWMKLNVEEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSAGKRYSPQFVKAAKLLHWNGHFKPWGRAASYADVWEKWYIPDPTGKFSLIRRHMDTSNIK", "length": 371 }, "evidence": [ { "id": "HGNC:24870", "url": "https://alliancegenome.org/gene/HGNC:24870#orthology", "database": "AGR" }, { "id": "MGI:1923735", "url": "https://alliancegenome.org/gene/MGI:1923735#orthology", "database": "AGR" }, { "id": "RGD:1359293", "url": "https://alliancegenome.org/gene/RGD:1359293#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-23#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NSU3-1", "protein_name": "Glycosyltransferase 8 domain-containing protein 1", "gene_name": "Glt8d1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFRKVNIIIWVLAVVLFLLVLHHNFLSLSSLLKNDISDSGIVGLQPIDFVASAHQHPVSERQEEIPVVIAASEDRLGGTIAAINSVHQNTRSNVMFYIVTFNSTADHLRSWLNSGSLKSIRYKIVNFDTKLLEGKVKQDPDQGESMKPLTFARFYLPILVPSAKKAIYMDDDVIVQGDILALYNTPLKPGHAAAFSEDCDSASTKVIIRGAGNQYNYIGYLDYKKERIRKLSMKASTCSFNPGVFVANLTEWKRQNVTNQLEKWMKLNVEEGLYSRTLAGSITTPPLLIVFYQQHSTIDPMWNVRHLGSSAGKRYSPQFVKAAKLLHWNGHFKPWGRTASYADVWEKWYIPDPTGKFSLIRRHMDTSNIK", "length": 371 }, "evidence": [ { 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"Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGTVHARSMDSYPMYGRDLGVNTDDMEVMEAVQETKQEVLENKDVVVQHVNIEGLGRTKEDYLGYEISDVFTARNLVEVMRKSHEARQRLLRLGIFRDVEVVIDISEGADALPNGLDVTFEVTELKRLTGSYNTMVGNNEGSMVLGIKLPNMLGRGEKLTFQFSYGTKETSYGLSFFKPQSGYFERNFTVNLYKVTGQFPWSSLKETDRGVSTELSLPLWMTDHTLKWEGVWRELGCLARSASFAVREESGHTLKSALSHTMVVDTRNSAILPRKGALLRINQELAGYTGGDANFLKEDVELQLNKQFIWGSVLSASLWGGMIYPLGAQPTSIADRFYLGGPTSVRGFGMYSIGPQSEGDYLGGEAYWAGGLHLYTPLPFRSNKGGLADLFRTHFFLNAGNICNLNYGEGPRAHLQKLAECIRWSYGAGIILRLGNIARLELNYCFPMGVQSGDRICDGVQFGAGIRFL", "length": 469, "header": "sp|Q5U3I0-1|SAM5B_DANRE Isoform 1 of Sorting and assembly machinery component 50 homolog B OS=Danio rerio OX=7955 GN=samm50b PE=2 SV=1 CANONICAL=Q5U3I0-1" }, "isoforms": [ { "isoform_ac": "Q5U3I0-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3I0/entry#Q5U3I0-1", "sequence": { "sequence": 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"ZFIN:ZDB-GENE-041114-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0033989", "url": "https://alliancegenome.org/gene/FB:FBgn0033989#orthology", "database": "AGR" }, { "id": "SGD:S000004971", "url": "https://alliancegenome.org/gene/SGD:S000004971#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6AXV4-1", "protein_name": "Sorting and assembly machinery component 50 homolog", "gene_name": "Samm50", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTVHARSLEPLPSSGTDFGALGEEAEFVEVEPEAKQEILENKDVVVQHVHFDGLERTKDDIIICEIGEVFKAKNLIEVMRRSHEAREKLLRLGIFRQVDVLIDTCHGEDALPNGLDVTFEVTELRRLTGSYNTMVGNNEGSMVLGLKLPNLLGRAEKVTFQFSYGTKETSYGLSFFKPQPGNFEKNFSVNLYKVTGQFPWSSLRETDRGVSAEYSFPLCKTSHTVKWEGVWRELGCLARTASFAVRKESGHSLKSSLSHAMVIDSRNSSILPRRGALLKVNQELAGYTGGDVSFIKEDFELQLNKPLVLDSVFSTSLWGGMLVPIGDKLSSIADRFYLGGPTSVRGFSMHSIGPQSEGDYLGGEAYWAGGLHLYTPLPFRPGQGGFGELFRTHFFLNAGNLCNLNYGEGPRAHIRKLAECIRWSYGAGIVLRLGNIARLELNYCIPMGVQRGDRICDGVQFGAGIRFL", "length": 469 }, "evidence": [ { "id": "RGD:1303219", "url": "https://alliancegenome.org/gene/RGD:1303219#orthology", "database": "AGR" }, { "id": "MGI:1915903", "url": "https://alliancegenome.org/gene/MGI:1915903#orthology", "database": "AGR" }, { "id": "HGNC:24276", "url": "https://alliancegenome.org/gene/HGNC:24276#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0033989", "url": "https://alliancegenome.org/gene/FB:FBgn0033989#orthology", "database": "AGR" }, { "id": "SGD:S000004971", "url": "https://alliancegenome.org/gene/SGD:S000004971#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q803G5-1", "protein_name": "Sorting and assembly machinery component 50 homolog A", "gene_name": "samm50a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGTVHARSLDPLPMQGPELGVQADDMDLGEPEREEKQEVLENKDVVVQHVHIDGLGRTKEDILTYEIADVFHAKNLIDVMKKSHEARQKLLRLGIFRHVEVVIDTAEGADALPNGLDVTFEVRELRRMTGSYNTMVGNNEGSMVLGIKLPNVLGRAEKLTFQFSYGTKETSYGLSFFKPQPGHFERNFSLNLYKVTGQFPWSSLRETDRGVSAEISFPIWRTSHTLKWEGVWRELGCLARTASFAVREESGHSLKSSLAHAMVIDTRNSTILPRKGALLKINQELAGYTGGDVSFLKEDFEIQLNKTLFWDSVLSTSLWGGMLLPLGEKASSIADRFYLGGPTSVRGFSMYSIGPQSEGDYLGGEAYWAGGVHLYTPLPFRPGRGGFGDLFRTHFFLNAGNLCNLNYGEGPRAHLSKLAECIRWSYGAGIVLRLGNIARLELNYCIPMGVQSGDRICDGVQFGAGIRFL", "length": 469 }, "evidence": [ { "id": "RGD:1303219", "url": "https://alliancegenome.org/gene/RGD:1303219#orthology", "database": "AGR" }, { "id": "MGI:1915903", "url": "https://alliancegenome.org/gene/MGI:1915903#orthology", "database": "AGR" }, { "id": "HGNC:24276", "url": "https://alliancegenome.org/gene/HGNC:24276#orthology", "database": "AGR" }, { "id": "FB:FBgn0033989", "url": "https://alliancegenome.org/gene/FB:FBgn0033989#orthology", "database": "AGR" }, { "id": "SGD:S000004971", "url": "https://alliancegenome.org/gene/SGD:S000004971#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BGH2-1", "protein_name": "Sorting and assembly machinery component 50 homolog", "gene_name": "Samm50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTVHARSLEPLPSSGTDFGALGEEAEFVEVEPEAKQEILENKDVVVQHVHFDGLGRTKDDIIICEIGEVFKAKNLIEVMRRSHEAREKLLRLGIFRQVDVLIDTCHGEDALPNGLDVTFEVTELRRLTGSYNTMVGNNEGSMVLGLKLPNLLGRAEKVTFQFSYGTKETSYGLSFFKPQPGNFERNFSVNLYKVTGQFPWSSLRETDRGVSAEYSFPLWKTSHTVKWEGVWRELGCLSRTASFAVRKESGHSLKSSLSHAMVIDSRNSSILPRRGALFKVNQELAGYTGGDVSFIKEDFELQLNKPLALDSVFSTSLWGGMLVPIGDKPSSIADRFYLGGPTSVRGFSMHSIGPQSEGDYLGGEAYWAGGLHLYTPLPFRPGQGGFGELFRTHFFLNAGNLCNLNYGEGPKAHIRKLAECIRWSYGAGVVLRLGNIARLELNYCIPMGVQGGDRICDGVQFGAGIRFL", "length": 469 }, "evidence": [ { "id": "RGD:1303219", "url": "https://alliancegenome.org/gene/RGD:1303219#orthology", "database": "AGR" }, { "id": "MGI:1915903", "url": "https://alliancegenome.org/gene/MGI:1915903#orthology", "database": "AGR" }, { "id": "HGNC:24276", "url": "https://alliancegenome.org/gene/HGNC:24276#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0033989", "url": "https://alliancegenome.org/gene/FB:FBgn0033989#orthology", "database": "AGR" }, { "id": "SGD:S000004971", "url": "https://alliancegenome.org/gene/SGD:S000004971#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V784-1", "protein_name": "SAM50-like protein CG7639", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPKSGRDGGASKDSKYDLSKISARVDRVNVSGLLRTHNDYVMRAADGLFKASNFQDLMLEAMSTKSYLHELGIFKDVSVHIDVSRGADASPQGYEVTFKGNEMSRMMGSAGTEIGQNEGSLRTELTIPNILGRGENISLQGSYSSTRANDLQLKFWKPFFHTRFKENRPEMSFSIFRQTDRFDISSFQTTNIGYLVDFSAHTMVGVDLTHSLQYENAIRDVGLLNKSVPFAIRDHCGPKLASLLRYSVVYDNRDGNVFPTRGIYLKSVNEYCGLGGNVAYTSSTAHGELNVPLFAGLVAQFCARVGVVKETKNTTQLPISSLFYCGGPLTLRGFKFGGAGPVVESTPIGAQSFWCTGAHLWAPLPFAGVFKNLASHFRMHFFYNIGNNNSFSTENMRSAFGMGLAVKLAERARIELNYCVPVRHQDTDRILNGFQFGIGYEFV", "length": 443 }, "evidence": [ { "id": "RGD:1303219", "url": "https://alliancegenome.org/gene/RGD:1303219#orthology", "database": "AGR" }, { "id": "MGI:1915903", "url": "https://alliancegenome.org/gene/MGI:1915903#orthology", "database": "AGR" }, { "id": "HGNC:24276", "url": "https://alliancegenome.org/gene/HGNC:24276#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0033989", "url": "https://alliancegenome.org/gene/FB:FBgn0033989#orthology", "database": "AGR" }, { "id": "SGD:S000004971", "url": "https://alliancegenome.org/gene/SGD:S000004971#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y512-1", "protein_name": "Sorting and assembly machinery component 50 homolog", "gene_name": "SAMM50", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTVHARSLEPLPSSGPDFGGLGEEAEFVEVEPEAKQEILENKDVVVQHVHFDGLGRTKDDIIICEIGDVFKAKNLIEVMRKSHEAREKLLRLGIFRQVDVLIDTCQGDDALPNGLDVTFEVTELRRLTGSYNTMVGNNEGSMVLGLKLPNLLGRAEKVTFQFSYGTKETSYGLSFFKPRPGNFERNFSVNLYKVTGQFPWSSLRETDRGMSAEYSFPIWKTSHTVKWEGVWRELGCLSRTASFAVRKESGHSLKSSLSHAMVIDSRNSSILPRRGALLKVNQELAGYTGGDVSFIKEDFELQLNKQLIFDSVFSASFWGGMLVPIGDKPSSIADRFYLGGPTSIRGFSMHSIGPQSEGDYLGGEAYWAGGLHLYTPLPFRPGQGGFGELFRTHFFLNAGNLCNLNYGEGPKAHIRKLAECIRWSYGAGIVLRLGNIARLELNYCVPMGVQTGDRICDGVQFGAGIRFL", "length": 469 }, "evidence": [ { "id": "RGD:1303219", "url": "https://alliancegenome.org/gene/RGD:1303219#orthology", "database": "AGR" }, { "id": "MGI:1915903", "url": "https://alliancegenome.org/gene/MGI:1915903#orthology", "database": "AGR" }, { "id": "HGNC:24276", "url": "https://alliancegenome.org/gene/HGNC:24276#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-30#orthology", "database": "AGR" }, { "id": "FB:FBgn0033989", "url": "https://alliancegenome.org/gene/FB:FBgn0033989#orthology", "database": "AGR" }, { "id": "SGD:S000004971", "url": "https://alliancegenome.org/gene/SGD:S000004971#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "SAM complex", "id": "GO:0001401", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001401", "evidence": [ { "database": "UniProtKB", "id": "Q5U3I0", "url": "https://www.uniprot.org/uniprotkb/Q5U3I0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein insertion into mitochondrial outer membrane", "id": "GO:0045040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045040", "evidence": [ { "database": "UniProtKB", "id": "Q5U3I0", "url": "https://www.uniprot.org/uniprotkb/Q5U3I0" } ], "pmid": "" }, { "name": "cristae formation", "id": "GO:0042407", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042407", "evidence": [ { "database": "UniProtKB", "id": "Q5U3I0", "url": "https://www.uniprot.org/uniprotkb/Q5U3I0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5U3I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3I0" }, { "id": "PRU01115", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU01115" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "POTRA", "eco_id": "ECO_0000255", "start_pos": 45, "end_pos": 125, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q5U3U0-1", "uniprot_ac": "Q5U3U0", "uniprot_id": "PHYD1_DANRE", "mass": { "chemical_mass": 33194.0, "monoisotopic_mass": 33194.0 }, "refseq": { "ac": "NP_001007446", "name": "phytanoyl-CoA dioxygenase domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007446" }, "gene_names": [ { "name": "phyhd1", "type": "recommended", "evidence": [ { "id": "Q5U3U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0" } ] }, { "name": "phyhd1", "type": "synonym", "evidence": [ { "id": "NP_001007446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007446" } ] }, { "name": "zgc:101639", "type": "synonym", "evidence": [ { "id": "NP_001007446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007446" }, { "id": "Q5U3U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0" } ] } ], "protein_names": [ { "name": "Phytanoyl-CoA dioxygenase domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "Q5U3U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0/entry#names_and_taxonomy" } ] }, { "name": "1.14.11.-", "type": "synonym", "evidence": [ { "id": "Q5U3U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0/entry#names_and_taxonomy" } ] }, { "name": "Protein PHYHD1", "type": "synonym", "evidence": [ { "id": "Q5U3U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0/entry#names_and_taxonomy" } ] }, { "name": "phytanoyl-CoA dioxygenase domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001007446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007446" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC085396.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085396.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007446", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007446" } ] }, { "annotation": "2-oxoglutarate(2OG)-dependent dioxygenase that catalyzes the conversion of 2-oxoglutarate to succinate and CO(2) in an iron-dependent manner. However, does not couple 2OG turnover to the hydroxylation of acyl-coenzyme A derivatives, implying that it is not directly involved in phytanoyl coenzyme-A metabolism. Does not show detectable activity towards fatty acid CoA thioesters.", "evidence": [ { "database": "UniProtKB", "id": "Q5U3U0", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0#function" }, { "database": "UniProtKB", "id": "Q5SRE7", "url": "https://www.uniprot.org/uniprotkb/Q5SRE7#function" }, { "database": "UniProtKB", "id": "A0AC58I8N9", "url": "https://www.uniprot.org/uniprotkb/A0AC58I8N9#function" }, { "database": "UniProtKB", "id": "ARBA00045487", "url": "https://www.uniprot.org/uniprotkb/ARBA00045487#function" }, { "database": "UniProtKB", "id": "A0AC58I8Q1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I8Q1#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U3U0", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "phyhd1", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041114-159", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-159", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5U3U0", "url": "https://alphafold.ebi.ac.uk/entry/Q5U3U0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000029905", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000029905", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "492804", "url": "https://www.ncbi.nlm.nih.gov/gene/492804", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KYSEDNW", "url": "https://omabrowser.org/oma/group/KYSEDNW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5U3U0", "url": "https://www.orthodb.org/?gene=Q5U3U0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20883", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20883", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20883:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20883:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05721", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05721", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5U3U0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5U3U0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007446", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007446", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58I8N9", "url": "https://www.uniprot.org/uniprotkb/A0AC58I8N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I8N9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I8N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I8Q1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I8Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I8Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I8Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5U3U0", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5U3U0-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041114-159", "url": "https://zfin.org/ZDB-GENE-041114-159", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDVLTDQDVQKFRDEGYLVLEGLLSPEECDALRRRMSEIIESMDVPEHCRTQFSTDHDEQLKTQGNADYFITSGDKIRFFFEKGVFDDKGEFVVPKEQSLNKIGHALHAYEPLFKRVTHSPKVQNICKKLELINPVILQSMYIFKQPGIGGEVTPHQDATFLYTQPLGRVMGVWVALEDAMQENGCLWFIPGSHNDGITRRMVRTPKGTFPLTDFIGREKDYDDKLFVPAPVKKGGAVLIHGEVVHRSAANTSDASRHVYTFHIMESENTVWSPENWLQATEELPFPSLYT", "length": 291, "header": "sp|Q5U3U0-1|PHYD1_DANRE Isoform 1 of Phytanoyl-CoA dioxygenase domain-containing protein 1 OS=Danio rerio OX=7955 GN=phyhd1 PE=2 SV=1 CANONICAL=Q5U3U0-1" }, "isoforms": [ { "isoform_ac": "A0AC58I8N9-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0/entry#A0AC58I8N9-1", "sequence": { "sequence": "MDVLTDQDVQKFRDEGYLVLEGLLSPEECDALRRRMSEIIESMDVPEHCRTQFSTDHDEQLKTQGNADYFITSGDKIRFFFEKGVFDDKGEFVVPKEQSLNKIGHALHAYEPLFKRVTHSPKVQNICKKLELINPVILQSMYIFKQPGIGGEVTPHQDATFLYTQPLGRVMGVWVALEDAMQENGCLWFIPGSHNDGITRRMVRTPKGTFPLTDFIGREKDYDDKLFVPAPVKKGGAVLIHGEVVHRSAANTSDASRHVYTFHIMESENTVWSPENWLQATEELPFPSLYT", "length": 291, "header": "tr|A0AC58I8N9-1|A0AC58I8N9_DANRE Computationally mapped isoform of Phytanoyl-CoA dioxygenase domain-containing protein 1 OS=Danio rerio OX=7955 GN=phyhd1 PE=1 SV=1 CANONICAL=Q5U3U0-1" }, "locus": {} }, { "isoform_ac": "A0AC58I8Q1-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0/entry#A0AC58I8Q1-1", "sequence": { "sequence": "MDVLTDQDVQKFRDEGYLVLEGLLSPEECDALRRRMSEIIESMDVPEHCRTQFSTDHDEQLKTQGNADYFITSGDKIRFFFEKGVFDDKGEFVVPKEQSLNKIGHALHAYEPLFKRVTHSPKVQNICKKLELINPVILQSMYIFKQPGIGGEVTPHQDATFLYTQPLGRVMGVWVALEDAMQENGCLWFIPGSHNDGITRRMVRTPKGTFPLTDFIGREKDYDDKLFVPAPVKKGGAVLIHGEVVHRSAANTSDASRHVYTFHIMESENTVWSPENWLQATEELPFPSLYT", "length": 291, "header": "tr|A0AC58I8Q1-1|A0AC58I8Q1_DANRE Computationally mapped isoform of Phytanoyl-CoA dioxygenase domain-containing protein 1 OS=Danio rerio OX=7955 GN=phyhd1 PE=1 SV=1 CANONICAL=Q5U3U0-1" }, "locus": {} }, { "isoform_ac": "Q5U3U0-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0/entry#Q5U3U0-1", "sequence": { "sequence": "MDVLTDQDVQKFRDEGYLVLEGLLSPEECDALRRRMSEIIESMDVPEHCRTQFSTDHDEQLKTQGNADYFITSGDKIRFFFEKGVFDDKGEFVVPKEQSLNKIGHALHAYEPLFKRVTHSPKVQNICKKLELINPVILQSMYIFKQPGIGGEVTPHQDATFLYTQPLGRVMGVWVALEDAMQENGCLWFIPGSHNDGITRRMVRTPKGTFPLTDFIGREKDYDDKLFVPAPVKKGGAVLIHGEVVHRSAANTSDASRHVYTFHIMESENTVWSPENWLQATEELPFPSLYT", "length": 291, "header": "sp|Q5U3U0-1|PHYD1_DANRE Isoform 1 of Phytanoyl-CoA dioxygenase domain-containing protein 1 OS=Danio rerio OX=7955 GN=phyhd1 PE=2 SV=1 CANONICAL=Q5U3U0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9T328-1", "protein_name": "Phytanoyl-CoA dioxygenase domain-containing protein 1", "gene_name": "PHYHD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MACLIPSQLQKFQEDGFLVLEGFLSADECEAMQRRIDEIVAKMDVPLHCRTEFSTQEEEQLRAQGSTDYFLSSGDKIRFFFEKGVFDKQGNFLVPPEKSINKIGHALHALDPIFRCVTHSHKVQALARSLGLQMPVVVQSMYIFKQPHFGGEVAPHQDASFLYTEPLGRVLGLWIALEDAMLENGCLWFIPGSHTGGVSRRMVRTPAGSVPGTSFLGSEPIRDNSLFVPTPVLRGALVLIHGEVVHKSEQNLSDRSRQAYTFHLMEAAGTIWSPDNWPANLPHGAAEYGGHSVTHTNGQDACIGH", "length": 305 }, "evidence": [ { "id": "Q5U3U0", "url": "https://omabrowser.org/oma/group/Q5U3U0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1RR60-1", "protein_name": "Phytanoyl-CoA dioxygenase domain-containing protein 1", "gene_name": "PHYHD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLSPSQLQKFQEDGFLVLEGFLSAAECVAMQQRIGELVAEMDVPRHCRTEFSTQEEEQLRAQGSTDYFLSSGDKIRFFFEKGVFDEKGNFLVPPEKAINKIGHALHAHDPVFRCITHSPKVQALARSLGLQMPVVVQSMYIFKQPHFGGEVSPHQDASFLYTEPLGRVLGMWMALEDATLENGCLWFIPGSHTGGVSRRMVRAPAGSAPGTSFLGSEPARDNNLFVPTPVRRGALVLIHGEVVHKSEQNLSDRSRQAYTFHLMDAADTVWSPENWLQPTAELPFPPLYT", "length": 291 }, "evidence": [ { "id": "Q5U3U0", "url": "https://omabrowser.org/oma/group/Q5U3U0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q54XH6-1", "protein_name": "Phytanoyl-CoA dioxygenase domain-containing protein 1 homolog", "gene_name": "phyhd1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLTEEQVAQYKKDGFLIIRNFNTTEEIDIVRGEMKKLIDELDTPSTISIFTTSEQERKVDDYFLGSGDKIRYFFEKGSIEDGKLIVPKDMAFNKVGHALHDLNPKFEEFSYSQKIHDLIYSLGIYNKALSGIMYIFKNQKIGGEVDIHQDSTFLHTTPLTTHAIWFAFEDSTIENGCLRGLPGSHTEGITRRFITDPNSESGCSFIKLAEDKQYNKSDFVALECKKGDIILLDGSVVHYSEPNTSPNSRHAYTLHFIEGDNGVIYENDNWLQSAKPFRVL", "length": 281 }, "evidence": [ { "id": "Q5U3U0", "url": "https://omabrowser.org/oma/group/Q5U3U0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5BJP9-1", "protein_name": "Phytanoyl-CoA dioxygenase domain-containing protein 1", "gene_name": "Phyhd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLSPSQLKKFQEDGFLLLEGFFTADECVVMQQRIGEIVAEMDVPLHCRTEFSTQEDEQLQTQGNTDYFLSSGDKIRFFFEKGVFDEKGNFLVPPEKSINKIGHALHAHDPVFRSITHSPKVQALVRSLGLQIPVVVQSMYIFKQPHFGGEVSPHQDATFLYTEPLGRVLGLWIATEDAMLENGCLWFIPGSHTSGVSRRMIRAPSDSGPGTSFLGSEPAWDNNLFVPLPVRRGGLVLIHGEVVHKSEQNLSDHSRQAYTFHLMEAAGTVWSPGNWLQPTTELPFPPLYI", "length": 291 }, "evidence": [ { "id": "RGD:1310377", "url": "https://alliancegenome.org/gene/RGD:1310377#orthology", "database": "AGR" }, { "id": "MGI:3612860", "url": "https://alliancegenome.org/gene/MGI:3612860#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-159", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-159#orthology", "database": "AGR" }, { "id": "HGNC:23396", "url": "https://alliancegenome.org/gene/HGNC:23396#orthology", "database": "AGR" }, { "id": "FB:FBgn0037819", "url": "https://alliancegenome.org/gene/FB:FBgn0037819#orthology", "database": "AGR" }, { "id": "Q5U3U0", "url": "https://omabrowser.org/oma/group/Q5U3U0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5SRE7-1", "protein_name": "Phytanoyl-CoA dioxygenase domain-containing protein 1", "gene_name": "PHYHD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACLSPSQLQKFQQDGFLVLEGFLSAEECVAMQQRIGEIVAEMDVPLHCRTEFSTQEEEQLRAQGSTDYFLSSGDKIRFFFEKGVFDEKGNFLVPPEKSINKIGHALHAHDPVFKSITHSFKVQTLARSLGLQMPVVVQSMYIFKQPHFGGEVSPHQDASFLYTEPLGRVLGVWIAVEDATLENGCLWFIPGSHTSGVSRRMVRAPVGSAPGTSFLGSEPARDNSLFVPTPVQRGALVLIHGEVVHKSKQNLSDRSRQAYTFHLMEASGTTWSPENWLQPTAELPFPQLYT", "length": 291 }, "evidence": [ { "id": "RGD:1310377", "url": "https://alliancegenome.org/gene/RGD:1310377#orthology", "database": "AGR" }, { "id": "MGI:3612860", "url": "https://alliancegenome.org/gene/MGI:3612860#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-159", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-159#orthology", "database": "AGR" }, { "id": "HGNC:23396", "url": "https://alliancegenome.org/gene/HGNC:23396#orthology", "database": "AGR" }, { "id": "FB:FBgn0037819", "url": "https://alliancegenome.org/gene/FB:FBgn0037819#orthology", "database": "AGR" }, { "id": "Q5U3U0", "url": "https://omabrowser.org/oma/group/Q5U3U0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DB26-1", "protein_name": "Phytanoyl-CoA dioxygenase domain-containing protein 1", "gene_name": "Phyhd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACLSPSQLKKFQEDGFLLLEGFFTADECVAMQQRIGEIVAEMDVPLHCRTEFSTQEDEQLQTQGKTDYFLSSGDKIRFFFEKGVFDEKGNFLVPPEKSINKIGHALHAHDPVFRSITHSPKVQALVRSLGLQMPVVVQSMYIFKQPHFGGEVSPHQDATFLYTEPLGRVLGLWIAMEDAMLENGCLWFIPGSHTRGVSRRMIRAPSDSGPGTSFLGSDPAWASNLFVPLPVRRGGLVLIHGEVVHKSEQNHSDHSRQAYTVHLMEAAGTVWSPGNWLQPTPELPFPPLYS", "length": 291 }, "evidence": [ { "id": "RGD:1310377", "url": "https://alliancegenome.org/gene/RGD:1310377#orthology", "database": "AGR" }, { "id": "MGI:3612860", "url": "https://alliancegenome.org/gene/MGI:3612860#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-159", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-159#orthology", "database": "AGR" }, { "id": "HGNC:23396", "url": "https://alliancegenome.org/gene/HGNC:23396#orthology", "database": "AGR" }, { "id": "FB:FBgn0037819", "url": "https://alliancegenome.org/gene/FB:FBgn0037819#orthology", "database": "AGR" }, { "id": "Q5U3U0", "url": "https://omabrowser.org/oma/group/Q5U3U0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VGY8-1", "protein_name": "1.14.11.-", "gene_name": "Phyhd1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHSKLLDELNENGYIVIEDFLTAEEVDSLYQAGRALCLDAPQNNRKIFSTIKQEDAQGKELYFMESGDKVRYFFEKGAVGDEGQLLVDPMIALNKVGHALHVEHPAFNAITFSNRVREICWQLNYNKPAVCQSMYIYKNPGVGGEVTPHQDSWFLHTDPNSAVGFWLALEDCTLQNGCLQFIKGSHKSGVHRRYLRNPDKDASELMVYDRAAPIYPQSSFTPMQVSKGTCILIHGNVVHKSEPNRSQKSRHAYTFHVIETENNVKYSEDNWLQAPKDKPFPVLFERKA", "length": 288 }, "evidence": [ { "id": "RGD:1310377", "url": "https://alliancegenome.org/gene/RGD:1310377#orthology", "database": "AGR" }, { "id": "MGI:3612860", "url": "https://alliancegenome.org/gene/MGI:3612860#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-159", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-159#orthology", "database": "AGR" }, { "id": "HGNC:23396", "url": "https://alliancegenome.org/gene/HGNC:23396#orthology", "database": "AGR" }, { "id": "FB:FBgn0037819", "url": "https://alliancegenome.org/gene/FB:FBgn0037819#orthology", "database": "AGR" }, { "id": "Q5U3U0", "url": "https://omabrowser.org/oma/group/Q5U3U0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9ZVF6-1", "protein_name": "Phytanoyl-CoA dioxygenase", "gene_name": "PAHX", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGITGSLTPDQLDFFHSQGYLVIESFASEDEIRGLRKRMDELLNQFDCSVSSIFSTKNQKHTTDNYFFESAEKISFFFEEKAFGDDGKLKQPKQLSINKVGHALHELDPLYKDFTYSSKFSSLASSLGYRRPVVMQSMYIFKQPGIGGEVVPHQDNSFVYTDPQSCTGLWIALEDSTLVNGCLWAIPGSHKNGLVRRFIRGDNGITFDQPSPSYEQKDFVSIEMKAGSLIAIHGDLIHQSFENLSSKSRHAYSLHVVESDGCKWAKDNWIQRAKMPEPLYVLP", "length": 283 }, "evidence": [ { "id": "Q5U3U0", "url": "https://omabrowser.org/oma/group/Q5U3U0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5U3U0", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0" } ], "pmid": "" }, { "name": "dioxygenase activity", "id": "GO:0051213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051213", "evidence": [ { "database": "UniProtKB", "id": "Q5U3U0", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "Q5U3U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0#function" }, { "id": "Q5U3U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0" } ], "binding_site_uniprot": 156, "amino_acid": "His", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000250", "start_pos": 156, "end_pos": 156, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5U3U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0#function" }, { "id": "Q5U3U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0" } ], "binding_site_uniprot": 158, "amino_acid": "Asp", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000250", "start_pos": 158, "end_pos": 158, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "Q5U3U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0#function" }, { "id": "Q5U3U0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U0" } ], "binding_site_uniprot": 246, "amino_acid": "His", "chebi_lig_id": "CHEBI_24875", "ligand": "Fe cation", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000250", "start_pos": 246, "end_pos": 246, "start_aa": "His", "end_aa": "His", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 251, "end_pos": 253 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q5U3U6-1", "uniprot_ac": "Q5U3U6", "uniprot_id": "BORA_DANRE", "mass": { "chemical_mass": 60335.0, "monoisotopic_mass": 60335.0 }, "refseq": { "ac": "NP_001007451", "name": "protein aurora borealis", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007451" }, "gene_names": [ { "name": "bora", "type": "recommended", "evidence": [ { "id": "Q5U3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6" } ] }, { "name": "bora", "type": "synonym", "evidence": [ { "id": "NP_001007451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007451" } ] }, { "name": "zgc:101616", "type": "synonym", "evidence": [ { "id": "NP_001007451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007451" }, { "id": "Q5U3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6" } ] } ], "protein_names": [ { "name": "Protein aurora borealis", "type": "recommended", "evidence": [ { "id": "Q5U3U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6/entry#names_and_taxonomy" } ] }, { "name": "aurora borealis", "type": "synonym", "evidence": [ { "id": "NP_001007451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007451" } ] }, { "name": "protein aurora borealis", "type": "synonym", "evidence": [ { "id": "NP_001007451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007451" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC085389.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898399, SAMEA898400 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085389.1. On Jan 30, 2008 this sequence version replaced XP_706771.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001007451", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007451" } ] }, { "annotation": "Required for the activation of aurka at the onset of mitosis.", "evidence": [ { "database": "UniProtKB", "id": "Q5U3U6", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U3U6", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "bora", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041114-165", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-165", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5U3U6", "url": "https://alphafold.ebi.ac.uk/entry/Q5U3U6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000042688", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000042688", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "555606", "url": "https://www.ncbi.nlm.nih.gov/gene/555606", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR023252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "STWIKEP", "url": "https://omabrowser.org/oma/group/STWIKEP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0AC58J2U2", "url": "https://www.orthodb.org/?gene=A0AC58J2U2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5U3U6", "url": "https://www.orthodb.org/?gene=Q5U3U6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14728", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14728", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14728:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14728:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15280", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15280", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5U3U6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5U3U6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DRE-2565942", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-2565942", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-69273", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-69273", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001007451", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007451", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58J2U2", "url": "https://www.uniprot.org/uniprotkb/A0AC58J2U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J2U2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J2U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5U3U6", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5U3U6-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041114-165", "url": "https://zfin.org/ZDB-GENE-041114-165", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGDIAKIHITPETPARPTILNPFESPNDYHRLHESVVPSPSVFKSCKSSSATPAKFKWSIDEMANLLPVEIDPEDIHRQAVFFSQARADSEIEEKRQHAIEQFFTKGAIVPSPWGPLTSKQSMKLPHHKSPLSPLVTEEIQPPKKINAICQTVLSLPVDFNLEKVLGDYYKTEELTEQVQESLSSSSLRRKLFLDGHDSGSESSTPSSPDRNSPSVHPSSRELMSSAIVSPLQCGIPTGTPMSGQFSSSPIQGQCRAYSLGSVTSPMFSERSSPAFKSPILSPIRLQQSVTPESGERKRLSFLSPNCVPKGSSDINMNRSGESPLVEGCSPIRSCSPFQSRPRNRACMWASPAHISPILHPVLHDKENIHITQHLPTMDLDATSTDPHAQQDSLHAESSESEASVAVSEQMEQDELFVKDTGENVETNGKECESDNEDEGENELGEEESCAWVPEEDTASPVRLSSTGTGSVPNAESTHMFLSLLAEGSITPYDTSMQVDSGYNTHSVCTTSLMDTLSSDSQSKEMLDTHTSEESGPFTRHTKPKLFVPPH", "length": 551, "header": "sp|Q5U3U6-1|BORA_DANRE Isoform 1 of Protein aurora borealis OS=Danio rerio OX=7955 GN=bora PE=2 SV=1 CANONICAL=Q5U3U6-1" }, "isoforms": [ { "isoform_ac": "A0AC58J2U2-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6/entry#A0AC58J2U2-1", "sequence": { "sequence": "MGDIAKIHITPETPARPTILNPFESPNDYHRLHESVVPSPSVFKSCKSSSATPAKFKWSIDEMANLLPVEIDPEDIHRQAVFFSQARADSEIEEKRQHAIEQFFTKGAIVPSPWGPLTSKQSMKLPHHKSPLSPLVTEEIQPPKKINAICQTVLSLPVDFNLEKVLGDYYKTEELTEQVQESLSSSSLRRKLFLDGHDSGSESSTPSSPDRNSPSVHPSSRELMSSAIVSPLQCGIPTGTPMSGQFSSSPIQGQCRAYSLGSVTSPMFSERSSPAFKSPILSPIRLQQSVTPESGERKRLSFLSPNCVPKGSSDMNVNRSGESPLVEGCSPIRSCSPFQSRPRNRACMWASPAHISPILHPVLHDKENIHITQHLPTMDLDATSTAPHAQQDSLHAESSESEASVAVSEQMEQDELFVKDTGENVETNEKECESDNEDEGENELREEESCAWVPEEDTASPVRLSSTGTGSVPNAESTHMFLSLLAEGSITPYDTSMQVDSGYNTHSVCTTSLMDTLSSDSQSKEMLDTHTSEESGPFTRHTKPKLFVPPH", "length": 551, "header": "tr|A0AC58J2U2-1|A0AC58J2U2_DANRE Computationally mapped isoform of Protein aurora borealis OS=Danio rerio OX=7955 GN=bora PE=3 SV=1 CANONICAL=Q5U3U6-1" }, "locus": {} }, { "isoform_ac": "Q5U3U6-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6/entry#Q5U3U6-1", "sequence": { "sequence": "MGDIAKIHITPETPARPTILNPFESPNDYHRLHESVVPSPSVFKSCKSSSATPAKFKWSIDEMANLLPVEIDPEDIHRQAVFFSQARADSEIEEKRQHAIEQFFTKGAIVPSPWGPLTSKQSMKLPHHKSPLSPLVTEEIQPPKKINAICQTVLSLPVDFNLEKVLGDYYKTEELTEQVQESLSSSSLRRKLFLDGHDSGSESSTPSSPDRNSPSVHPSSRELMSSAIVSPLQCGIPTGTPMSGQFSSSPIQGQCRAYSLGSVTSPMFSERSSPAFKSPILSPIRLQQSVTPESGERKRLSFLSPNCVPKGSSDINMNRSGESPLVEGCSPIRSCSPFQSRPRNRACMWASPAHISPILHPVLHDKENIHITQHLPTMDLDATSTDPHAQQDSLHAESSESEASVAVSEQMEQDELFVKDTGENVETNGKECESDNEDEGENELGEEESCAWVPEEDTASPVRLSSTGTGSVPNAESTHMFLSLLAEGSITPYDTSMQVDSGYNTHSVCTTSLMDTLSSDSQSKEMLDTHTSEESGPFTRHTKPKLFVPPH", "length": 551, "header": "sp|Q5U3U6-1|BORA_DANRE Isoform 1 of Protein aurora borealis OS=Danio rerio OX=7955 GN=bora PE=2 SV=1 CANONICAL=Q5U3U6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 205, "start_aa": "Thr", "end_pos": 205, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr205", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 52, "start_aa": "Thr", "end_pos": 52, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr52", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-DRE-2565942", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-2565942", "resource": "Reactome", "description": "Regulation of PLK1 Activity at G2/M Transition" }, { "id": "R-DRE-69273", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-69273", "resource": "Reactome", "description": "Cyclin A/B1/B2 associated events during G2/M transition" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5M864-1", "protein_name": "Protein aurora borealis", "gene_name": "Bora", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDVSELKMQITPATPGRIPVLNPFESPSDYSNLHEQTLASPSVFKSTKLPTPGEFRWSIDQLAVINPVEIDPEEIHRQASYLSLSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHDGKQPSELHPSKCLTSNGDSPVGKKPSLPSQKCNAACQTLLSLPVDFNLEAVLGDYFRADDSVDQSPGNLSSSSLRRKLFLDVNGSISDSLPSASPRSPPNSARGSLEGQFSSSPIQNNAKKYSLGSLTTSPSAICSPTFSPIALQVGKTPLSEHRKFTFHSPEASSGGSSTGIANPSIRSPYIDGCSPIKNWSPRGLRGGPQYLSSLIRVPFALETHSEDEEDNVSSTDVAALGTNAVAAPLQQLDCEPLACGDPFVVSAMPVTQSQSSTCEKDLGLLGDFESERDHDTVDMVDPIDTADESTWIKEPVGNGNSPMAEFVSGIAFSIENSHMCMSPLAESSVLPCESSNVQMDSGYNTQTCGSNITDIVGTESYCKENVTQSFEAQMKPQVNNIKQDHTVQRCWMKTTSPSQCSSL", "length": 534 }, "evidence": [ { "id": "MGI:1924994", "url": "https://alliancegenome.org/gene/MGI:1924994#orthology", "database": "AGR" }, { "id": "HGNC:24724", "url": "https://alliancegenome.org/gene/HGNC:24724#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-165", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-165#orthology", "database": "AGR" }, { "id": "RGD:1309522", "url": "https://alliancegenome.org/gene/RGD:1309522#orthology", "database": "AGR" }, { "id": "FB:FBgn0259791", "url": "https://alliancegenome.org/gene/FB:FBgn0259791#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PGQ7-1", "protein_name": "Protein aurora borealis", "gene_name": "BORA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDVKESKMQITPETPGRIPVLNPFESPSDYSNLHEQTLASPSVFKSTKLPTPGKFRWSIDQLAVINPVEIDPEDIHRQALYLSHSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHEGKQLSQCHSSKCTNINSDSPVGKKLTIHSEKSDAACQTLLSLPVDFNLENILGDYFRADEFADQSPGNLSSSSLRRKLFLDGNGSISDSLPSASPGSPHSGVQTSLEMFYSIDLSPVKCRSPLQTPSSGQFSSSPIQASAKKYSLGSITSPSPISSPTFSPIEFQIGETPLSEQRKFTVHSPDASSGTNSNGITNPCIRSPYIDGCSPIKNWSPMRLQMYSGGTQYRTSVIQIPFTLETQGEDEEDKENIPSTDVSSPAMDAAGIHLRQFSNEASTHGTHLVVTAMSVTQNQSSASEKELALLQDVEREKDNNTVDMVDPIEIADETTWIKEPVDNGSLPMTDFVSGIAFSIENSHMCMSPLAESSVIPCESSNIQMDSGYNTQNCGSNIMDTVGAESYCKESDAQTCEVESKSQAFNMKQDHTTQRCWMKTASPFQCSSP", "length": 559 }, "evidence": [ { "id": "MGI:1924994", "url": "https://alliancegenome.org/gene/MGI:1924994#orthology", "database": "AGR" }, { "id": "HGNC:24724", "url": "https://alliancegenome.org/gene/HGNC:24724#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-165", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-165#orthology", "database": "AGR" }, { "id": "RGD:1309522", "url": "https://alliancegenome.org/gene/RGD:1309522#orthology", "database": "AGR" }, { "id": "FB:FBgn0259791", "url": "https://alliancegenome.org/gene/FB:FBgn0259791#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BS90-1", "protein_name": "Protein aurora borealis", "gene_name": "Bora", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDVSELKMQITPETPGRIPVLNPFESPSDYSNLHEQTLASPSIFKSTKLPTPGKFRWSIDQLAIINPVEIDPEEIHRQASYLRLSRIDKDVEDKRQKAIEEFFTKDVIVPSPWTDHDGKQPSELHPSKCLSSHDDSPDGKKPSLPSQKCNAACQTLLSLPVDFNLEAILGDYFREEDFVAHTPGNLSSSSLRRKLFLDGNGSICDPLPSPSPGSPPCSARGSLEGQFSSSPIQNSVKKYSLGSVTTSPSAISSPTFSPIALQGGKTPLSEPRKLTFHSPEASCATASTGIVNPSIRSPYIDGCSPIKNWSPRRLRGGPQCLSSLVRIPFTLEAHSEDEEADVSCTGAAPLSTNACGEPRVVTAMSVTQSHSGIAEKERAVLDDAESERENDTVDMVDPTDTVAESTWIKEPVDDGNSPMTDSASGIAFSIENSHMCMSPLAESSVLPYESSAIQMNSDYNTQTCVSNITDIVGTERYCKENVTHTNVPVPFEVEMKSQVNNVTPGHTAQRCWMKSPRPSQCSRP", "length": 525 }, "evidence": [ { "id": "MGI:1924994", "url": "https://alliancegenome.org/gene/MGI:1924994#orthology", "database": "AGR" }, { "id": "HGNC:24724", "url": "https://alliancegenome.org/gene/HGNC:24724#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-165", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-165#orthology", "database": "AGR" }, { "id": "RGD:1309522", "url": "https://alliancegenome.org/gene/RGD:1309522#orthology", "database": "AGR" }, { "id": "FB:FBgn0259791", "url": "https://alliancegenome.org/gene/FB:FBgn0259791#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VVR2-1", "protein_name": "Protein aurora borealis", "gene_name": "bora", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYNDEVRTPQALKNRYITNVNGLKCRARRNSHSNSSNSSAASATPTNGGKENGKYSPQMSGNVCTPPPKRLHKVRNPFEGAMADRLHLPLIASPSLFRSRTPQLSSTQFEWNIDEVSQLKPADVEPHETQFHDSPDPEQESKAQLAISAFFKESLIVPSPVDCPLRKQRIILNCSEDNTPISNKSRRMRDCEVQTELTLPPILPKALEDALRPYFQPHLAGRLSGRSKSSGGPDIFNSSMRRKLFDLHNVIVLGEQDTAEPSRSMVGSSPQGKQTMFAGRLSDSASGESSFGCLSPIRNLCGLPPGTPDNGTCSGKRKLLMHELELPSPIAPSEHLSRRLVHSKVEISVTEQHDTLSERTALKFTPDRSSSPMGGGLEHSDCSINQRVRRLRVNSTRQVVIETGDQPLFEETEGEEEEAESEDDEEADAMQLSTVSFNCSSSNSDTPRGHKRHRSAQRKNLSQSFSANLEEEADQTQGGAGSIQPAEPPSVAMPQQGARIPLYRADSGFNETSSTTFAFSQDLPLDVSMACCSTPSTRS", "length": 539 }, "evidence": [ { "id": "MGI:1924994", "url": "https://alliancegenome.org/gene/MGI:1924994#orthology", "database": "AGR" }, { "id": "HGNC:24724", "url": "https://alliancegenome.org/gene/HGNC:24724#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-165", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-165#orthology", "database": "AGR" }, { "id": "RGD:1309522", "url": "https://alliancegenome.org/gene/RGD:1309522#orthology", "database": "AGR" }, { "id": "FB:FBgn0259791", "url": "https://alliancegenome.org/gene/FB:FBgn0259791#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "Q5U3U6", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5U3U6", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "Q5U3U6", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "Q5U3U6", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6" } ], "pmid": "" }, { "name": "regulation of protein localization", "id": "GO:0032880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032880", "evidence": [ { "database": "UniProtKB", "id": "Q5U3U6", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6" } ], "pmid": "" }, { "name": "regulation of mitotic spindle organization", "id": "GO:0060236", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060236", "evidence": [ { "database": "UniProtKB", "id": "Q5U3U6", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6" } ], "pmid": "" }, { "name": "regulation of mitotic nuclear division", "id": "GO:0007088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007088", "evidence": [ { "database": "UniProtKB", "id": "Q5U3U6", "url": "https://www.uniprot.org/uniprotkb/Q5U3U6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 52, 205 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 318, "end_pos": 320 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q5U3V7-1", "uniprot_ac": "Q5U3V7", "uniprot_id": "S2543_DANRE", "mass": { "chemical_mass": 38518.0, "monoisotopic_mass": 38518.0 }, "refseq": { "ac": "NP_001004497", "name": "solute carrier family 25 member 43", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004497" }, "gene_names": [ { "name": "slc25a43", "type": "recommended", "evidence": [ { "id": "Q5U3V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3V7" } ] }, { "name": "si:bz46j2.1", "type": "synonym", "evidence": [ { "id": "NP_001004497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004497" } ] }, { "name": "si:rp71-46j2.1", "type": "synonym", "evidence": [ { "id": "NP_001004497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004497" } ] }, { "name": "slc25a43", "type": "synonym", "evidence": [ { "id": "NP_001004497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004497" } ] }, { "name": "wu:fc65c10", "type": "synonym", "evidence": [ { "id": "NP_001004497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004497" } ] }, { "name": "zgc:101590", "type": "synonym", "evidence": [ { "id": "NP_001004497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004497" }, { "id": "Q5U3V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3V7" } ] } ], "protein_names": [ { "name": "Solute carrier family 25 member 43", "type": "recommended", "evidence": [ { "id": "Q5U3V7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3V7/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial carrier", "type": "synonym", "evidence": [ { "id": "NP_001004497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004497" } ] }, { "name": "solute carrier family 25 member 43", "type": "synonym", "evidence": [ { "id": "NP_001004497", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004497" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC085377.1, BI892318.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085377.1. On or before Feb 8, 2008 this sequence version replaced XP_001335978.1, XP_001335022.1, NP_001004497.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001004497", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004497" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U3V7", "url": "https://www.uniprot.org/uniprotkb/Q5U3V7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "slc25a43", "url": "https://www.uniprot.org/uniprotkb/Q5U3V7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030616-69", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-69", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5U3V7", "url": "https://alphafold.ebi.ac.uk/entry/Q5U3V7", "database": "AlphaFoldDB", "categories": [] }, { "id": "796731", "url": "https://www.ncbi.nlm.nih.gov/gene/796731", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002067", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002067", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:796731", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796731", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5U3V7", "url": "https://www.orthodb.org/?gene=Q5U3V7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24089", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24089", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00153", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00153", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5U3V7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5U3V7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001004497", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004497", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5U3V7", "url": "https://www.uniprot.org/uniprotkb/Q5U3V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5U3V7-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3V7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030616-69", "url": "https://zfin.org/ZDB-GENE-030616-69", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MATVKKDARLTSSQSLMCVGFAGIFSKTVTSPLEVVKILSQVGTFHCKRGFLHSFVLICQNEGLRAFWKGNMVSCLRLFPYSAIHLATYKNIVNLHIDELGDISQWRAIVAGGLAGISAALATYPLEVVETRLIAQNCQEPTYRGLLHSLSVIYRNEGLQALYRGFSLTVLGAVPFSVGCYAVYINLDKLWQERHVRFTSLQNFINGCLAAGVAQTLSFPFETVKKKMQAQSLVLPHCGGVDVHFNGMADCFRQVIKNKGVMALWSGLTANMVKIVPYFGLLFSCFEMCKQVCLYRNGYIISPPSYKLKPGVDQSLGPYELQEFKRYLRNRKSHKAQSSSIGNRW", "length": 345, "header": "sp|Q5U3V7-1|S2543_DANRE Isoform 1 of Solute carrier family 25 member 43 OS=Danio rerio OX=7955 GN=slc25a43 PE=2 SV=1 CANONICAL=Q5U3V7-1" }, "isoforms": [ { "isoform_ac": "Q5U3V7-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3V7/entry#Q5U3V7-1", "sequence": { "sequence": "MATVKKDARLTSSQSLMCVGFAGIFSKTVTSPLEVVKILSQVGTFHCKRGFLHSFVLICQNEGLRAFWKGNMVSCLRLFPYSAIHLATYKNIVNLHIDELGDISQWRAIVAGGLAGISAALATYPLEVVETRLIAQNCQEPTYRGLLHSLSVIYRNEGLQALYRGFSLTVLGAVPFSVGCYAVYINLDKLWQERHVRFTSLQNFINGCLAAGVAQTLSFPFETVKKKMQAQSLVLPHCGGVDVHFNGMADCFRQVIKNKGVMALWSGLTANMVKIVPYFGLLFSCFEMCKQVCLYRNGYIISPPSYKLKPGVDQSLGPYELQEFKRYLRNRKSHKAQSSSIGNRW", "length": 345, "header": "sp|Q5U3V7-1|S2543_DANRE Isoform 1 of Solute carrier family 25 member 43 OS=Danio rerio OX=7955 GN=slc25a43 PE=2 SV=1 CANONICAL=Q5U3V7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:796731", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796731", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2A3V2-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "Slc25a43", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATWRRDGRLTGSQRLLCAGLAGAFSLSLTAPLELATVLAQVGKVQSHSLGLWATGRRVWLSEGPRALWKGNGVACLRLFPCSMVQLAAYRKFVVLFMDDLGRISQWSSIVTGSLAGMVSTIVTYPTDLIKTRLMVQNVLEPSYRGLIHAFSTIYQQEGFLALYRGVSLTVLGAVPFSAGSLLVYMNLEKVWNGPRDRFSHLQNFANVCVAAAVSQTLSFPFDTVKRKMQAQSPYLPHYGGVDVHFSGAADCFRQIVKTQGVLGLWNGLTANLLKVVPYFGVMFSMFEFCKRIFLYQNGYTLSPLTYKLTPGVDQSLKPQELRELKKFFKRRKLHSKTPPW", "length": 341 }, "evidence": [ { "id": "HGNC:30557", "url": "https://alliancegenome.org/gene/HGNC:30557#orthology", "database": "AGR" }, { "id": "RGD:1559928", "url": "https://alliancegenome.org/gene/RGD:1559928#orthology", "database": "AGR" }, { "id": "MGI:2684854", "url": "https://alliancegenome.org/gene/MGI:2684854#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-69", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-69#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZG94-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "Slc25a43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATWRRDGRLTGSQRFLCAGLAGAFSLSLTAPLELATVLAQVGRVQSHSQGLWATGRRVWLSEGPRALWKGNGVACLRLFPCSVVQLAAYRKFVVLFMDDLGRISQWSSIVAGSLAGMVSTIVTYPTDLIKTRLIVQNMLEPSYRGLIHALSTIYQQEGFLALYRGASLTVLGAVPFSAGSLLVYMNLEKIWTGPRDRFSHLQNFATVCVAAAVSQAVSFPFDTVKRKMQAQSPYLPHYGGVDIHFSGAVDCFRQIVKTQGVLGLWNGLTANLLKVVPYFGVMFGMFEFCKRIFLYQNGYTLSPLTYKLTPGVDQSLKPQELRELKKLF", "length": 329 }, "evidence": [ { "id": "HGNC:30557", "url": "https://alliancegenome.org/gene/HGNC:30557#orthology", "database": "AGR" }, { "id": "RGD:1559928", "url": "https://alliancegenome.org/gene/RGD:1559928#orthology", "database": "AGR" }, { "id": "MGI:2684854", "url": "https://alliancegenome.org/gene/MGI:2684854#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-69", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-69#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WUT9-1", "protein_name": "Solute carrier family 25 member 43", "gene_name": "SLC25A43", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATWRRDGRLTGGQRLLCAGLAGTLSLSLTAPLELATVLAQVGVVRGHARGPWATGHRVWRAEGLRALWKGNAVACLRLFPCSAVQLAAYRKFVVLFTDDLGHISQWSSIMAGSLAGMVSTIVTYPTDLIKTRLIMQNILEPSYRGLLHAFSTIYQQEGFLALYRGVSLTVVGALPFSAGSLLVYMNLEKIWNGPRDQFSLPQNFANVCLAAAVTQTLSFPFETVKRKMQAQSPYLPHSGGVDVHFSGAVDCFRQIVKAQGVLGLWNGLTANLLKIVPYFGIMFSTFEFCKRICLYQNGYILSPLSYKLTPGVDQSLQPQELRELKKFFKTRKPKPKKPTL", "length": 341 }, "evidence": [ { "id": "HGNC:30557", "url": "https://alliancegenome.org/gene/HGNC:30557#orthology", "database": "AGR" }, { "id": "RGD:1559928", "url": "https://alliancegenome.org/gene/RGD:1559928#orthology", "database": "AGR" }, { "id": "MGI:2684854", "url": "https://alliancegenome.org/gene/MGI:2684854#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-69", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-69#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "Q5U3V7", "url": "https://www.uniprot.org/uniprotkb/Q5U3V7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "Q5U3V7", "url": "https://www.uniprot.org/uniprotkb/Q5U3V7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q5U3W3-1", "uniprot_ac": "Q5U3W3", "uniprot_id": "RUN3B_DANRE", "mass": { "chemical_mass": 50503.0, "monoisotopic_mass": 50503.0 }, "refseq": { "ac": "NP_001007417", "name": "RUN domain-containing protein 3B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007417" }, "gene_names": [ { "name": "rundc3b", "type": "recommended", "evidence": [ { "id": "Q5U3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3W3" } ] }, { "name": "rundc3b", "type": "synonym", "evidence": [ { "id": "NP_001007417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007417" } ] }, { "name": "zgc:101561", "type": "synonym", "evidence": [ { "id": "NP_001007417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007417" }, { "id": "Q5U3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3W3" } ] } ], "protein_names": [ { "name": "RUN domain-containing protein 3B", "type": "recommended", "evidence": [ { "id": "Q5U3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3W3/entry#names_and_taxonomy" } ] }, { "name": "RUN domain-containing protein 3B", "type": "synonym", "evidence": [ { "id": "NP_001007417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007417" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC085369.1, BC165585.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN06645147 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC085369.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007417" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5U3W3", "url": "https://www.uniprot.org/uniprotkb/Q5U3W3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rundc3b", "url": "https://www.uniprot.org/uniprotkb/Q5U3W3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041114-121", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-121", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5U3W3", "url": "https://alphafold.ebi.ac.uk/entry/Q5U3W3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17700", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17700", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "492775", "url": "https://www.ncbi.nlm.nih.gov/gene/492775", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:492775", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492775", "database": "KEGG Pathway", "categories": [ "Enzyme and 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5U3W3-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3W3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041114-121", "url": "https://zfin.org/ZDB-GENE-041114-121", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASLNLGFSGARKKAAARIRAVERRNLITVCRFSVKTLIDRSCFETIDDTSAEFINFVSILEHILSHRLKGQVSWFGYESPRSFWDFIRMACSKVPHSCIHSIENMENVRSSRAKGRAWIRVALMEKRLSEYISAALRDFKTTRRFYEEGALLLGEEAGLLADTLIGLNAIDFSFCLKGEGLDEDCPVVIDYTPYLKFTQTSDSISSDEEEMRTLGSSGSEAGTPESHMAASLMADQSSWFSKSKRLEQKYRVVLEQRGYLEELVRLREAQLSESVSQNKALLQRLTDTEISHKLEKEQLEIIILELQDQLTVLKNHDLRSRQELTSHLTNQWPSPGALDGNAVALDTLLYRKRTGPWEEKSFPSLEQLSADMSLSQTSLDPVQLNTHSLDSKAGLAHWHREGKEDTPSLRGLCGSLTSMASYKSLASLKSSEYLASPTTDMTSPGLTPS", "length": 450, "header": "sp|Q5U3W3-1|RUN3B_DANRE Isoform 1 of RUN domain-containing protein 3B OS=Danio rerio OX=7955 GN=rundc3b PE=2 SV=1 CANONICAL=Q5U3W3-1" }, "isoforms": [ { "isoform_ac": "Q5U3W3-1", "url": "https://www.uniprot.org/uniprotkb/Q5U3W3/entry#Q5U3W3-1", "sequence": { "sequence": "MASLNLGFSGARKKAAARIRAVERRNLITVCRFSVKTLIDRSCFETIDDTSAEFINFVSILEHILSHRLKGQVSWFGYESPRSFWDFIRMACSKVPHSCIHSIENMENVRSSRAKGRAWIRVALMEKRLSEYISAALRDFKTTRRFYEEGALLLGEEAGLLADTLIGLNAIDFSFCLKGEGLDEDCPVVIDYTPYLKFTQTSDSISSDEEEMRTLGSSGSEAGTPESHMAASLMADQSSWFSKSKRLEQKYRVVLEQRGYLEELVRLREAQLSESVSQNKALLQRLTDTEISHKLEKEQLEIIILELQDQLTVLKNHDLRSRQELTSHLTNQWPSPGALDGNAVALDTLLYRKRTGPWEEKSFPSLEQLSADMSLSQTSLDPVQLNTHSLDSKAGLAHWHREGKEDTPSLRGLCGSLTSMASYKSLASLKSSEYLASPTTDMTSPGLTPS", "length": 450, "header": "sp|Q5U3W3-1|RUN3B_DANRE Isoform 1 of RUN domain-containing protein 3B OS=Danio rerio OX=7955 GN=rundc3b PE=2 SV=1 CANONICAL=Q5U3W3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:492775", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492775", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3B7K9-1", "protein_name": "RUN domain-containing protein 3B", "gene_name": "Rundc3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASRSLGGLSGSRGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAVLEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEEGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGTFPAVIDYTPYLKFEQSSDSISSDEEELRTFGSSDSEGSTPENVGPPLILDENSWFNKCKRVRQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQASLDPGHSQEGDGKQDSLNFIGEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDCLASPTTEITSPGLTPS", "length": 403 }, "evidence": [ { "id": "RGD:1587590", "url": "https://alliancegenome.org/gene/RGD:1587590#orthology", "database": "AGR" }, { "id": "MGI:2685286", "url": "https://alliancegenome.org/gene/MGI:2685286#orthology", "database": "AGR" }, { "id": "HGNC:30286", "url": "https://alliancegenome.org/gene/HGNC:30286#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-121", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-121#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PDC0-1", "protein_name": "RUN domain-containing protein 3B", "gene_name": "Rundc3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRSLGGLSGSRGGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAVLEQILSHRLKGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGTFPAVIDYTPYLKFEQSSDSISSDEEELRTFGSSDSESSTPENVGPPLILDENTWFNKCKRVRQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLKSYQSLDQLSAEVSLSQASLDPSHSQEGDGKQDSLNFIGEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDCLASPTTELTSPGLTPS", "length": 408 }, "evidence": [ { "id": "RGD:1587590", "url": "https://alliancegenome.org/gene/RGD:1587590#orthology", "database": "AGR" }, { "id": "MGI:2685286", "url": "https://alliancegenome.org/gene/MGI:2685286#orthology", "database": "AGR" }, { "id": "HGNC:30286", "url": "https://alliancegenome.org/gene/HGNC:30286#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-121", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-121#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96NL0-1", "protein_name": "RUN domain-containing protein 3B", "gene_name": "RUNDC3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRSLGGLSGIRGGGGGGGKKSLSARNAAVERRNLITVCRFSVKTLIDRSCFETIDDSSPEFNNFAAILEQILSHRLKEISQSCRWLAHLQIPLQGQVTWFGYESPRSFWDYIRVACRKVSQNCICSIENMENVSSSRAKGRAWIRVALMEKHLSEYISTALRDFKTTRRFYEDGAIVLGEEANMLAGMLLGLNAIDFSFCLKGEGLDGSFPAVIDYTPYLKYIQSSDSISSDEEELRTLGSSGSESSTPENVGPPFLMDENSWFNKCKRVKQKYQLTLEQKGYLEELLRLRENQLSESVSQNKILLQRIEDSDLAHKLEKEQLEYIIVELQDQLTVLKNNDLRSRQELTAHLTNQWPSPGALDVNAVALDTLLYRKHNKQWYEKSYQSLDQLSAEVSLSQTSLDPGQSQEGDGKQDTLNVMSEGKEDTPSLLGLCGSLTSVASYKSLTSLKSNDYLASPTTEMTSPGLTPS", "length": 473 }, "evidence": [ { "id": "RGD:1587590", "url": "https://alliancegenome.org/gene/RGD:1587590#orthology", "database": "AGR" }, { "id": "MGI:2685286", "url": "https://alliancegenome.org/gene/MGI:2685286#orthology", "database": "AGR" }, { "id": "HGNC:30286", "url": "https://alliancegenome.org/gene/HGNC:30286#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-121", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-121#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5U3W3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5U3W3" }, { "id": "PRU00178", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00178" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RUN", "eco_id": "ECO_0000255", "start_pos": 48, "end_pos": 180, "start_aa": "Asp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q5VSC8-1", "uniprot_ac": "Q5VSC8", "uniprot_id": "Q5VSC8_DANRE", "mass": { "chemical_mass": 96258.0, "monoisotopic_mass": 96258.0 }, "refseq": { "ac": "NP_001025417", "name": "phospholipase DDHD1b", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025417" }, "gene_names": [ { "name": "ddhd1b", "type": "recommended", "evidence": [ { "id": "Q5VSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8" } ] }, { "name": "ddhd1b", "type": "synonym", "evidence": [ { "id": "NP_001025417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025417" } ] }, { "name": "ddhd1", "type": "synonym", "evidence": [ { "id": "NP_001025417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025417" }, { "id": "Q5VSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8" } ] }, { "name": "si:dkey-29m11.6", "type": "synonym", "evidence": [ { "id": "NP_001025417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025417" }, { "id": "Q5VSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8" } ] }, { "name": "si:dkey-63j12.5", "type": "synonym", "evidence": [ { "id": "NP_001025417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025417" }, { "id": "Q5VSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8" } ] } ], "protein_names": [ { "name": "DDHD domain containing 1", "type": "synonym", "evidence": [ { "id": "NP_001025417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025417" } ] }, { "name": "Phospholipase DDHD1b", "type": "synonym", "evidence": [ { "id": "Q5VSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8/entry#names_and_taxonomy" } ] }, { "name": "phospholipase DDHD1b", "type": "synonym", "evidence": [ { "id": "NP_001025417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025417" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01008422.1, GDQH01013237.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505378 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000020.1. On Aug 6, 2005 this sequence version replaced XP_698882.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001025417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025417" } ] } ], "disease": [ { "disease_id": "DOID:0110779", "recommended_name": { "id": "DOID:0110779", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110779", "name": "hereditary spastic paraplegia 28", "description": "A hereditary spastic paraplegia that has_material_basis_in mutation in the DDHD1 gene on chromosome 14q22." }, "synonyms": [ { "id": "DOID:0110779", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110779", "name": "SPG28", "description": "" }, { "id": "DOID:0110779", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110779", "name": "autosomal recessive spastic paraplegia 28", "description": "" }, { "id": "DOID:0110779", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110779", "name": "autosomal recessive spastic paraplegia type 28", "description": "" }, { "id": "MONDO:0012256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012256", "name": "hereditary spastic paraplegia 28", "description": "Autosomal recessive spastic paraplegia type 28 is a pure form of hereditary spastic paraplegia characterized by a childhood or adolescent onset of slowly progressive, pure crural muscle spastic paraparesis which manifests with mild lower limb weakness, gait difficulties, extensor plantar responses, and hyperreflexia of lower extremities. Less common manifestations reported include cerebellar oculomotor disturbance with saccadic eye pursuit, pes cavus and scoliosis. Some patients also present pin and vibration sensory loss in distal legs." }, { "id": "MONDO:0012256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012256", "name": "DDHD1 autosomal recessive pure spastic paraplegia", "description": "" }, { "id": "MONDO:0012256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012256", "name": "SPG28", "description": "" }, { "id": "MONDO:0012256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012256", "name": "autosomal recessive pure spastic paraplegia caused by mutation in DDHD1", "description": "" }, { "id": "MONDO:0012256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012256", "name": "autosomal recessive spastic paraplegia type 28", "description": "" }, { "id": "MONDO:0012256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012256", "name": "hereditary spastic paraplegia 28", "description": "" }, { "id": "MONDO:0012256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012256", "name": "hereditary spastic paraplegia type 28", "description": "" }, { "id": "MONDO:0012256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012256", "name": "spastic paraplegia 28, autosomal recessive", "description": "" }, { "id": "MIM:609340", "resource": "MIM", "url": "https://www.omim.org/entry/609340", "name": "Spastic paraplegia 28, autosomal recessive", "description": "Spastic paraplegia 28, autosomal recessive" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110779", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110779" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5VSC8", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ddhd1b", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040724-18", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-18", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000037042", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000037042", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "570320", "url": "https://www.ncbi.nlm.nih.gov/gene/570320", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004177", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004177", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570320", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570320", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TKARWPS", "url": "https://omabrowser.org/oma/group/TKARWPS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5VSC8", "url": "https://www.orthodb.org/?gene=Q5VSC8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23509", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23509", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23509:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23509:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02862", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02862", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001025417", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025417", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5VSC8", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5VSC8-1", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040724-18", "url": "https://zfin.org/ZDB-GENE-040724-18", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSACQDKSSLSCSESRENVSGSEWGRMDDGCASCFNDPTGDAIHGGMDAVQPGITLDGHLPLPPGQLMLGLVEEGFAGYHSHLGSDPDTDYLDIPGDPNYSESDGNVATKKRNRSNSSRHRGEVVTELGPEEVRWFYKEDKRTWKPFVGHDSLKIELAYRKYCELNPEEVKRRDATEEAEDLFESSSGCEEPAVRRQSAAVAAQPVPDSADAGCSADDSVFRSDSVNVDAVCVRGGLYEVDIKGKSCYPVYWNQQDHIPVMRGQWFTDGTWLPLEEEDSDLIELEHLACFRGQQMKDTFDTEAVATTVDSKDAIHSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEAALEDTPPETTHIVFVVHGIGQKMDQGRIIRNTSMMRDAARKMEEKHFSDRINEHVEFLPVEWRSKLALDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDEITRGLTKELNRLYMLFCERNPEFAEKGKVSIVSHSLGCVITFDIMTGWDPVRFVHEDVPDVMEADVSRQERQLLEELRLTYLRIRDLEDRLQNFQTSSSRPSPALKFKVENFFCMGSPLAVFLALRGVRPGSGGTQDHILPTSICQRLFNIFHPTDPVAYRLEPLILKHYSNITPVQIHWYNTTSPTPYDQIRPTLLNPSKENASVSDTESLPSPCTSPPQPRRHYSESITNLGKASIMGAASIGKGIGGILFSRFSRSSGQVGGVEEETSDSEGGTCEKGDENRSVDLDDKPDEKTEEKIEEKTGDTSMSQSASTIMDYSSLELEKRIDFELREGLVESRYWSAVTSHTAYWCSHDVALFLLTFLYRPNEANDMAEDNLES", "length": 859, "header": "tr|Q5VSC8-1|Q5VSC8_DANRE Isoform 1 of Phospholipase DDHD1b OS=Danio rerio OX=7955 GN=ddhd1b PE=3 SV=1 CANONICAL=Q5VSC8-1" }, "isoforms": [ { "isoform_ac": "Q5VSC8-1", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8/entry#Q5VSC8-1", "sequence": { "sequence": "MSACQDKSSLSCSESRENVSGSEWGRMDDGCASCFNDPTGDAIHGGMDAVQPGITLDGHLPLPPGQLMLGLVEEGFAGYHSHLGSDPDTDYLDIPGDPNYSESDGNVATKKRNRSNSSRHRGEVVTELGPEEVRWFYKEDKRTWKPFVGHDSLKIELAYRKYCELNPEEVKRRDATEEAEDLFESSSGCEEPAVRRQSAAVAAQPVPDSADAGCSADDSVFRSDSVNVDAVCVRGGLYEVDIKGKSCYPVYWNQQDHIPVMRGQWFTDGTWLPLEEEDSDLIELEHLACFRGQQMKDTFDTEAVATTVDSKDAIHSLKLSRSHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEAALEDTPPETTHIVFVVHGIGQKMDQGRIIRNTSMMRDAARKMEEKHFSDRINEHVEFLPVEWRSKLALDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDEITRGLTKELNRLYMLFCERNPEFAEKGKVSIVSHSLGCVITFDIMTGWDPVRFVHEDVPDVMEADVSRQERQLLEELRLTYLRIRDLEDRLQNFQTSSSRPSPALKFKVENFFCMGSPLAVFLALRGVRPGSGGTQDHILPTSICQRLFNIFHPTDPVAYRLEPLILKHYSNITPVQIHWYNTTSPTPYDQIRPTLLNPSKENASVSDTESLPSPCTSPPQPRRHYSESITNLGKASIMGAASIGKGIGGILFSRFSRSSGQVGGVEEETSDSEGGTCEKGDENRSVDLDDKPDEKTEEKIEEKTGDTSMSQSASTIMDYSSLELEKRIDFELREGLVESRYWSAVTSHTAYWCSHDVALFLLTFLYRPNEANDMAEDNLES", "length": 859, "header": "tr|Q5VSC8-1|Q5VSC8_DANRE Isoform 1 of Phospholipase DDHD1b OS=Danio rerio OX=7955 GN=ddhd1b PE=3 SV=1 CANONICAL=Q5VSC8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Evolution of two-pore domain potassium channels and their gene expression in zebrafish embryos.", "journal": "Dev. Dyn.", "date": "2024", "authors": "Park Sung Jun, Silic Martin R, Staab Peyton L, Chen Jiapei, Zackschewski Ethan L, Zhang GuangJun", "evidence": [ { "database": "UniProtKB", "id": "Q5VSC8", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8" } ], "reference": [ { "type": "PubMed", "id": "38270285", "url": "https://glygen.org/publication/PubMed/38270285" } ] } ], "pathway": [ { "id": "dre:570320", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570320", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZSB2-1", "protein_name": "DDHD domain containing 1", "gene_name": "Ddhd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNYPGRGAPRSPERNGRGGGAWELGSDAAGVFGGGGCCFEHQPGDGVPLSLLRAEPLHLAPGADDLSHLALDPCLSDENYDFSSAESGSSLRYYSEGESAGGGSSSSPPPPLVAPNSGGGGAAGGGPGDRKRSRPGGCAARHRYEVVTELGPEEVRWFYKEDKKTWKPFIGYDSLRIELAFRSLLQTTGSRARSADRDGDRVCGPTSSFREDDEDRACGFCPRAVGPEPEMEELVTIEPVCVRGGLYEVDVTQGECYPVYWNQADKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLSCFRGQQMQENFDIEMSKSIDGKDVVYHIPPFSLPSLFKWRGYKESTDATGLKRKRSQAVHSFKLSRNHVDWHSMDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEEKHFANHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGWNPVRLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLREIEDRLHGLKAPSGSQTPALKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPNFLNPAKEPTSASESENIAAIPSPVTSPVLSRRHYGESITNIGKASILGAASIGKGLGGMLFSRFGRSSTPQPSEPSKDSAEEEKKPVSSPSTTTVATQTLPHSSSGFLDSAYFRLQESFFYLPQLLFPENVMQSKDDSLVELEHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFMYKHEHDSEAKTSLDSI", "length": 917 }, "evidence": [ { "id": "MGI:2150302", "url": "https://alliancegenome.org/gene/MGI:2150302#orthology", "database": "AGR" }, { "id": "HGNC:19714", "url": "https://alliancegenome.org/gene/HGNC:19714#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12204-1", "protein_name": "Probable phospholipase YOR022C, mitochondrial", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRFTHRGLPSSTRFRNIFVRLNHIYVPWFYAIDVPNSKPYLPTYQTLHSPKKFKPFSVDDSNRLEKASKRQERRPVLVNEDYLFKVDLSHMELSPTYWEGPTYQVRRGVWFDSSNQPLSSDLTSEIEGLYKQLKFDDSNDDPTTTPPAESQDIFRLKGKYPVDKENEGEQKNGSSNKDENESTFKFILFANKQTAFLLSDLDGGKLQLAFLRSNLAQSLPINATMITRSYKYSSSATTKQTSTSFKAAKTPQTEVADGSNSSKSRSIETKLEKKVSNLFNLSDFLQLFNGNASKDQDDAQSLEKQMETDYNNADNSQGANASSKIEDGKNSGASDRQIRSNRRDVDNLILCVHGIGQTLGKKYEYVNFAHTVNLLRSNMKKIYNNSEKLQSLNTAPDYKSNCNVQVLPITWRHSISFQTDAKEENIENPDLPTLSQVTVNGVLPLRKLLADGLLDILLYVEPYYQDMILQQVTSQLNKTYRIFKEFNPEFDGKVHLVGHSLGSMILFDILSKQKKYELEFQVDNLFFIGSPIGLLKLIQRTKIGDRPEFPNDLERKLTVQRPQCKDIYNVYHVCDPISYRMEPLVSKEMAHYEQTYLPHCSEAYGLTSKVLEFGENIWKDLPGTDENNLQSKKTSPEKKEVKLSENLTRMLTGLNYTGRLDYAMSPSLLEVDFISAIKSHVSYFEEPDIAAFILKEILSKHENASEIYVKRKTG", "length": 715 }, "evidence": [ { "id": "MGI:2150302", "url": "https://alliancegenome.org/gene/MGI:2150302#orthology", "database": "AGR" }, { "id": "HGNC:19714", "url": "https://alliancegenome.org/gene/HGNC:19714#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q80YA3-1", "protein_name": "Phospholipase DDHD1", "gene_name": "Ddhd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTSHIVFVVHGIGQKMDQGRIIKNTAMMREAARKMEEKHFSNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMMGWNPGGLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLREIEDRLHGLKAPSISQTPALKFKVENFFCMGSPLAVFLALRGIRPGNSGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPNFLNPAKEPTSVSDSENIAAIPSPVTSPVLSRRHYGESITNIGKASILGAASIGKGLGGMLFSRFGRSSASQPSEPSKDSLEDDKKPSASPSTTTVATQTLPHSGSGFLDSAYFRLQESFFYLPQLLFPENVMQSKDDSLVELEHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFMYKHEHDTEAKPSLGSL", "length": 547 }, "evidence": [ { "id": "MGI:2150302", "url": "https://alliancegenome.org/gene/MGI:2150302#orthology", "database": "AGR" }, { "id": "HGNC:19714", "url": "https://alliancegenome.org/gene/HGNC:19714#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-18", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-18#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NEL9-1", "protein_name": "Phospholipase DDHD1", "gene_name": "DDHD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNYPGRGSPRSPEHNGRGGGGGAWELGSDARPAFGGGVCCFEHLPGGDPDDGDVPLALLRGEPGLHLAPGTDDHNHHLALDPCLSDENYDFSSAESGSSLRYYSEGESGGGGSSLSLHPPQQPPLVPTNSGGGGATGGSPGERKRTRLGGPAARHRYEVVTELGPEEVRWFYKEDKKTWKPFIGYDSLRIELAFRTLLQTTGARPQGGDRDGDHVCSPTGPASSSGEDDDEDRACGFCQSTTGHEPEMVELVNIEPVCVRGGLYEVDVTQGECYPVYWNQADKIPVMRGQWFIDGTWQPLEEEESNLIEQEHLNCFRGQQMQENFDIEVSKSIDGKDAVHSFKLSRNHVDWHSVDEVYLYSDATTSKIARTVTQKLGFSKASSSGTRLHRGYVEEATLEDKPSQTTHIVFVVHGIGQKMDQGRIIKNTAMMREAARKIEERHFSNHATHVEFLPVEWRSKLTLDGDTVDSITPDKVRGLRDMLNSSAMDIMYYTSPLYRDELVKGLQQELNRLYSLFCSRNPDFEEKGGKVSIVSHSLGCVITYDIMTGWNPVRLYEQLLQKEEELPDERWMSYEERHLLDELYITKRRLKEIEERLHGLKASSMTQTPALKFKVENFFCMGSPLAVFLALRGIRPGNTGSQDHILPREICNRLLNIFHPTDPVAYRLEPLILKHYSNISPVQIHWYNTSNPLPYEHMKPSFLNPAKEPTSVSENEGISTIPSPVTSPVLSRRHYGESITNIGKASILGAASIGKGLGGMLFSRFGRSSTTQSSETSKDSMEDEKKPVASPSATTVGTQTLPHSSSGFLDSAYFRLQESFFNLPQLLFPENVMQNKDNALVELDHRIDFELREGLVESRYWSAVTSHTAYWSSLDVALFLLTFMYKHEHDDDAKPNLDPI", "length": 900 }, "evidence": [ { "id": "MGI:2150302", "url": "https://alliancegenome.org/gene/MGI:2150302#orthology", "database": "AGR" }, { "id": "HGNC:19714", "url": "https://alliancegenome.org/gene/HGNC:19714#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-18", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-18#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "Q5VSC8", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "Q5VSC8", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8" } ], "pmid": "" }, { "name": "phospholipase activity", "id": "GO:0004620", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004620", "evidence": [ { "database": "UniProtKB", "id": "Q5VSC8", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" }, { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" }, { "start_pos": 659, "end_pos": 661, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 761, "end_pos": 763, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q5VSC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5VSC8" }, { "id": "PS51043", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51043" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DDHD", "eco_id": "ECO_0000259", "start_pos": 582, "end_pos": 845, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 116, "end_pos": 118 }, { "start_pos": 18, "end_pos": 20 }, { "start_pos": 402, "end_pos": 404 }, { "start_pos": 460, "end_pos": 462 }, { "start_pos": 649, "end_pos": 651 }, { "start_pos": 659, "end_pos": 661 }, { "start_pos": 680, "end_pos": 682 }, { "start_pos": 761, "end_pos": 763 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5XIX8-1", "uniprot_ac": "Q5XIX8", "uniprot_id": "BORC5_DANRE", "mass": { "chemical_mass": 23544.0, "monoisotopic_mass": 23544.0 }, "refseq": { "ac": "NP_001007053", "name": "BLOC-1-related complex subunit 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007053" }, "gene_names": [ { "name": "borcs5", "type": "recommended", "evidence": [ { "id": "Q5XIX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8" } ] }, { "name": "borcs5", "type": "synonym", "evidence": [ { "id": "NP_001007053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007053" } ] }, { "name": "im:7155461", "type": "synonym", "evidence": [ { "id": "NP_001007053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007053" }, { "id": "Q5XIX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8" } ] }, { "name": "loh12cr1", "type": "synonym", "evidence": [ { "id": "NP_001007053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007053" }, { "id": "Q5XIX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8" } ] }, { "name": "zgc:92915", "type": "synonym", "evidence": [ { "id": "NP_001007053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007053" }, { "id": "Q5XIX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8" } ] } ], "protein_names": [ { "name": "BLOC-1-related complex subunit 5", "type": "recommended", "evidence": [ { "id": "Q5XIX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8/entry#names_and_taxonomy" } ] }, { "name": "BLOC-1-related complex subunit 5", "type": "synonym", "evidence": [ { "id": "NP_001007053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007053" } ] }, { "name": "loss of heterozygosity 12 chromosomal region 1 protein homolog", "type": "synonym", "evidence": [ { "id": "NP_001007053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007053" } ] }, { "name": "loss of heterozygosity, 12, chromosomal region 1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001007053", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007053" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC083541.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505370, SAMEA3505371 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083541.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001007053", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007053" } ] }, { "annotation": "As part of a BORC-like complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, this complex may couple lysosomes to microtubule plus-end-directed kinesin motor.", "evidence": [ { "database": "UniProtKB", "id": "Q5XIX8", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8#function" }, { "database": "UniProtKB", "id": "Q969J3", "url": "https://www.uniprot.org/uniprotkb/Q969J3#function" } ] } ], "disease": [ { "disease_id": "DOID:0050861", "recommended_name": { "id": "DOID:0050861", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5XIX8", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "borcs5", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041010-83", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-83", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5XIX8", "url": "https://alphafold.ebi.ac.uk/entry/Q5XIX8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000077830", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077830", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22789", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22789", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "449650", "url": "https://www.ncbi.nlm.nih.gov/gene/449650", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:449650", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449650", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EGRPHDP", "url": "https://omabrowser.org/oma/group/EGRPHDP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5XIX8", "url": "https://www.orthodb.org/?gene=Q5XIX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31634", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31634", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31634:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31634:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10158", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10158", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5XIX8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5XIX8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001007053", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007053", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AA52Z6G4", "url": "https://www.uniprot.org/uniprotkb/A0AA52Z6G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AA52Z6G4-1", "url": "https://www.uniprot.org/uniprotkb/A0AA52Z6G4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5XIX8", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5XIX8-1", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041010-83", "url": "https://zfin.org/ZDB-GENE-041010-83", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGAEQSGDADHKHSDFSASVVPSPAKHRAKMDDIVVVAQGTQSLRNIHNDPDVIKLQEIPTFQPLLKGVLSGQTSPSTVCLEKLDSAQVLQLCVRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVEALFSIMQERQKRYAKYAEQIQKVNEMSMILRRIQMGIDQTVPLMERLNNMLPESLFWMLPMEHITFALDCLSYAWIRCFLA", "length": 207, "header": "sp|Q5XIX8-1|BORC5_DANRE Isoform 1 of BLOC-1-related complex subunit 5 OS=Danio rerio OX=7955 GN=borcs5 PE=2 SV=1 CANONICAL=Q5XIX8-1" }, "isoforms": [ { "isoform_ac": "A0AA52Z6G4-1", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8/entry#A0AA52Z6G4-1", "sequence": { "sequence": "MGAEQSGDADHKHSDFSASVVPSPAKHRAKMDDIVVVAQGTQSLRNIHNDPDVIKLQEIPTFQPLLKGVLSGQTSPSTVCLEKLDSAQVLQLCVRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVEALFSIMQERQKRYAKYAEQIQKVNEMSMILRRIQMGIDQTVPLMERLNNMLPESERLEPFCMKPDGDSK", "length": 195, "header": "tr|A0AA52Z6G4-1|A0AA52Z6G4_DANRE Computationally mapped isoform of BLOC-1-related complex subunit 5 OS=Danio rerio OX=7955 GN=borcs5 PE=1 SV=1 CANONICAL=Q5XIX8-1" }, "locus": {} }, { "isoform_ac": "Q5XIX8-1", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8/entry#Q5XIX8-1", "sequence": { "sequence": "MGAEQSGDADHKHSDFSASVVPSPAKHRAKMDDIVVVAQGTQSLRNIHNDPDVIKLQEIPTFQPLLKGVLSGQTSPSTVCLEKLDSAQVLQLCVRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVEALFSIMQERQKRYAKYAEQIQKVNEMSMILRRIQMGIDQTVPLMERLNNMLPESLFWMLPMEHITFALDCLSYAWIRCFLA", "length": 207, "header": "sp|Q5XIX8-1|BORC5_DANRE Isoform 1 of BLOC-1-related complex subunit 5 OS=Danio rerio OX=7955 GN=borcs5 PE=2 SV=1 CANONICAL=Q5XIX8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:449650", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449650", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B1H257-1", "protein_name": "BLOC-1-related complex subunit 5", "gene_name": "Borcs5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSEQSAEAESRPGDLNASVTPSPAKHRAKMDDIVVVAQGSQASRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNARLEKLDSQQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLFCFMQERQKRYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLMERLNSMLPEAERLEPFSMRPERERH", "length": 195 }, "evidence": [ { "id": "RGD:1307624", "url": "https://alliancegenome.org/gene/RGD:1307624#orthology", "database": "AGR" }, { "id": "MGI:1915024", "url": "https://alliancegenome.org/gene/MGI:1915024#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-83", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-83#orthology", "database": "AGR" }, { "id": "HGNC:17950", "url": "https://alliancegenome.org/gene/HGNC:17950#orthology", "database": "AGR" }, { "id": "FB:FBgn0030346", "url": "https://alliancegenome.org/gene/FB:FBgn0030346#orthology", "database": "AGR" }, { "id": "Q5XIX8", "url": "https://omabrowser.org/oma/group/Q5XIX8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08DP2-1", "protein_name": "BLOC-1-related complex subunit 5", "gene_name": "BORCS5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSEQSSEAESRPNDLNSSVTPSPAKHRAKMDDIVVVAQGSQASRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNAKLEKLDSQQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLFSFMQERQKRYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLLERLNSLLPEAERLEPFSVKPDRELRL", "length": 196 }, "evidence": [ { "id": "Q5XIX8", "url": "https://omabrowser.org/oma/group/Q5XIX8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5ZJA9-1", "protein_name": "BLOC-1-related complex subunit 5", "gene_name": "BORCS5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGVNGSHASPSPAKQRAKMDDIVVVAPGTQSSRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNTKLEKLDPHQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLYSFMQERQKKYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLMERLNSMLPESEQLEPFSMKPDREIKS", "length": 185 }, "evidence": [ { "id": "Q5XIX8", "url": "https://omabrowser.org/oma/group/Q5XIX8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q969J3-1", "protein_name": "BLOC-1-related complex subunit 5", "gene_name": "BORCS5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSEQSSEAESRPNDLNSSVTPSPAKHRAKMDDIVVVAQGSQASRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNAKLEKLDSQQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLFSFMQERQKRYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLLDRLNSMLPEGERLEPFSMKPDRELRL", "length": 196 }, "evidence": [ { "id": "RGD:1307624", "url": "https://alliancegenome.org/gene/RGD:1307624#orthology", "database": "AGR" }, { "id": "MGI:1915024", "url": "https://alliancegenome.org/gene/MGI:1915024#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-83", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-83#orthology", "database": "AGR" }, { "id": "HGNC:17950", "url": "https://alliancegenome.org/gene/HGNC:17950#orthology", "database": "AGR" }, { "id": "FB:FBgn0030346", "url": "https://alliancegenome.org/gene/FB:FBgn0030346#orthology", "database": "AGR" }, { "id": "Q5XIX8", "url": "https://omabrowser.org/oma/group/Q5XIX8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D920-1", "protein_name": "BLOC-1-related complex subunit 5", "gene_name": "Borcs5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSEQSAEAESRPGDLNASVTPSPAKHRAKMDDIVVVAQGSQASRNVSNDPDVIKLQEIPTFQPLLKGLLSGQTSPTNAKLEKLDSQQVLQLCLRYQDHLHQCAEAVAFDQNALVKRIKEMDLSVETLFCFMQERQKRYAKYAEQIQKVNEMSAILRRIQMGIDQTVPLMERLNSMLPEAERLEPFSMKPERERH", "length": 195 }, "evidence": [ { "id": "RGD:1307624", "url": "https://alliancegenome.org/gene/RGD:1307624#orthology", "database": "AGR" }, { "id": "MGI:1915024", "url": "https://alliancegenome.org/gene/MGI:1915024#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-83", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-83#orthology", "database": "AGR" }, { "id": "HGNC:17950", "url": "https://alliancegenome.org/gene/HGNC:17950#orthology", "database": "AGR" }, { "id": "FB:FBgn0030346", "url": "https://alliancegenome.org/gene/FB:FBgn0030346#orthology", "database": "AGR" }, { "id": "Q5XIX8", "url": "https://omabrowser.org/oma/group/Q5XIX8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VYT1-1", "protein_name": "BLOC-1-related complex subunit 5", "gene_name": "BORCS5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGAEHSQQRAEADGHEIFDGRQPPGAGTGSLGDGSSMMLAATAAANKRRGVGHRQQTTGGAGGTVVGPGAGVGPASIVIASKQIIAEAASPGGSELSRPPSPPLSVCSDLPYVSYTDRPIGDSPKIRSKPAHMLQQSSASRAAARKSHPSGLTSAVKPKRPQSTASSHNIVIVRPGAIDAGEDVDMDLARLRNIPQFLPVLRESITSATNTRDAEILERLNSQHLINICTRMQTHLNLCASYVASEQNHLVERTKVVSNSITTLFAGFVDMQKTYASYAEQFAKIRSISHQLSRCNSLLHENIASLEAINNFLDDEDRLEPFVWRTDDNKLRGEAEGAIGGNSSRLWRL", "length": 349 }, "evidence": [ { "id": "RGD:1307624", "url": "https://alliancegenome.org/gene/RGD:1307624#orthology", "database": "AGR" }, { "id": "MGI:1915024", "url": "https://alliancegenome.org/gene/MGI:1915024#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-83", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-83#orthology", "database": "AGR" }, { "id": "HGNC:17950", "url": "https://alliancegenome.org/gene/HGNC:17950#orthology", "database": "AGR" }, { "id": "FB:FBgn0030346", "url": "https://alliancegenome.org/gene/FB:FBgn0030346#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "Q5XIX8", "url": "https://www.uniprot.org/uniprotkb/Q5XIX8" } ], "pmid": "" }, { "name": "synaptic vesicle membrane", "id": "GO:0030672", "url": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q5XIY2-1", "uniprot_ac": "Q5XIY2", "uniprot_id": "TLC4B_DANRE", "mass": { "chemical_mass": 29927.0, "monoisotopic_mass": 29927.0 }, "refseq": { "ac": "NP_001005924", "name": "TLC domain-containing protein 4-B isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005924" }, "gene_names": [ { "name": "tlcd4b", "type": "recommended", "evidence": [ { "id": "Q5XIY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY2" } ] }, { "name": "tlcd4b", "type": "synonym", "evidence": [ { "id": "NP_001005924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005924" } ] }, { "name": "tmem56b", "type": "synonym", "evidence": [ { "id": "NP_001005924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005924" }, { "id": "Q5XIY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY2" } ] }, { "name": "tmem56", "type": "synonym", "evidence": [ { "id": "NP_001005924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005924" }, { "id": "Q5XIY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY2" } ] }, { "name": "zgc:92864", "type": "synonym", "evidence": [ { "id": "NP_001005924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005924" }, { "id": "Q5XIY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY2" } ] } ], "protein_names": [ { "name": "TLC domain-containing protein 4-B", "type": "recommended", "evidence": [ { "id": "Q5XIY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY2/entry#names_and_taxonomy" } ] }, { "name": "TLC domain-containing protein 4-B isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001005924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005924" } ] }, { "name": "TLC domain-containing protein 4-B", "type": "synonym", "evidence": [ { "id": "NP_001005924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005924" } ] }, { "name": "Transmembrane protein 56-B", "type": "synonym", "evidence": [ { "id": "Q5XIY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY2/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 56-B", "type": "synonym", "evidence": [ { "id": "NP_001005924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005924" } ] }, { "name": "transmembrane protein 56b", "type": "synonym", "evidence": [ { "id": "NP_001005924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005924" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01041249.1, SRR32588726.56171638.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Apr 20, 2018 this sequence version replaced XP_005168534.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001005924", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005924" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5XIY2", "url": "https://www.uniprot.org/uniprotkb/Q5XIY2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tlcd4b", "url": "https://www.uniprot.org/uniprotkb/Q5XIY2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041010-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-90", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5XIY2", "url": "https://alphafold.ebi.ac.uk/entry/Q5XIY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "449652", "url": "https://www.ncbi.nlm.nih.gov/gene/449652", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:449652", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449652", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HANNHTD", "url": "https://omabrowser.org/oma/group/HANNHTD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5XIY2", "url": "https://www.orthodb.org/?gene=Q5XIY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13439", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13439", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13439:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13439:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5XIY2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5XIY2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001005924", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005924", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TH76", "url": "https://www.uniprot.org/uniprotkb/A0AB32TH76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TH76-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TH76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5XIY2", "url": "https://www.uniprot.org/uniprotkb/Q5XIY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5XIY2-1", "url": "https://www.uniprot.org/uniprotkb/Q5XIY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041010-90", "url": "https://zfin.org/ZDB-GENE-041010-90", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDMREVYVVAGSFVGFQLFFSCVSPVLSSNFTQGYGKLPPNKLNDWNSRLVSTVHALIVGLFCLYILWYDDAVNEDPVWGDPNLVKLNVAITCGYLFYDLLLLACNWSTMGDVFFVCHHLAALYAYGYVLTRGVLPYFANFRLISELSTPFVNQRWFFEALAYPRTHQLVVANGIAMAVVFFLVRIAVMPPYWAKVFGIIYSPTFEKLGLAIQVAWIISCVCLDILNIIWMYKIARGCYKVITGKLKGRKADSKKTTCVNNHTD", "length": 264, "header": "sp|Q5XIY2-1|TLC4B_DANRE Isoform 1 of TLC domain-containing protein 4-B OS=Danio rerio OX=7955 GN=tlcd4b PE=2 SV=1 CANONICAL=Q5XIY2-1" }, "isoforms": [ { "isoform_ac": "A0AB32TH76-1", "url": "https://www.uniprot.org/uniprotkb/Q5XIY2/entry#A0AB32TH76-1", "sequence": { "sequence": "MGDVFFVCHHLAALYAYGYVLTRGVLPYFANFRLISELSTPFVNQRWFFEALAYPRTHQLVVANGIAMAVVFFLVRIAVMPPYWAKVFGIIYSPTFEKLGLAIQVAWIISCVCLDILNIIWMYKIARGCYKVITGKLKGRKADSKKTTCVNNHTD", "length": 155, "header": "tr|A0AB32TH76-1|TLC4B_DANRE Computationally mapped isoform of TLC domain-containing protein 4-B OS=Danio rerio OX=7955 GN=tlcd4b PE=2 SV=1 CANONICAL=Q5XIY2-1" }, "locus": {} }, { "isoform_ac": "Q5XIY2-1", "url": "https://www.uniprot.org/uniprotkb/Q5XIY2/entry#Q5XIY2-1", "sequence": { "sequence": "MDMREVYVVAGSFVGFQLFFSCVSPVLSSNFTQGYGKLPPNKLNDWNSRLVSTVHALIVGLFCLYILWYDDAVNEDPVWGDPNLVKLNVAITCGYLFYDLLLLACNWSTMGDVFFVCHHLAALYAYGYVLTRGVLPYFANFRLISELSTPFVNQRWFFEALAYPRTHQLVVANGIAMAVVFFLVRIAVMPPYWAKVFGIIYSPTFEKLGLAIQVAWIISCVCLDILNIIWMYKIARGCYKVITGKLKGRKADSKKTTCVNNHTD", "length": 264, "header": "sp|Q5XIY2-1|TLC4B_DANRE Isoform 1 of TLC domain-containing protein 4-B OS=Danio rerio OX=7955 GN=tlcd4b PE=2 SV=1 CANONICAL=Q5XIY2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Functional analysis of human hematopoietic stem cell gene expression using zebrafish.", "journal": "PLoS Biol.", "date": "2005", "authors": "Eckfeldt Craig E, Mendenhall Eric M, Flynn Catherine M, Wang Tzu-Fei, Pickart Michael A, Grindle Suzanne M, Ekker Stephen C, Verfaillie Catherine M", "evidence": [ { "database": "UniProtKB", "id": "A0AB32TH76", "url": "https://www.uniprot.org/uniprotkb/A0AB32TH76" } ], "reference": [ { "type": "PubMed", "id": "16089502", "url": "https://glygen.org/publication/PubMed/16089502" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0AB32TH76", "url": "https://www.uniprot.org/uniprotkb/A0AB32TH76" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:449652", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449652", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NG98-1", "protein_name": "Transmembrane protein 56-B-like", "gene_name": "si:dkey-10f21.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEPLSPQVLVVVAGSFLSFQWLFHRVSPWVFQHLCGGFLRLSPTQKTEWNSRAVSTVHALVVGLFCLYIYIFDESIQKDPVWGDATLVKLNVAVTSGYLMSDLLLMFTSWESIGEKYFVIHHFAALYAYYYVLSQGILPYFANFRLLSEFSTPFVNQRWFFHMLGYHKLSKPSLLNGVAMAFTFFLVRIAVIPGYYSHMYSVFGTDDFYRLPIGARCAWVISSVSLDVMNIMWMRRIIRGCLKVLRSAWTRPAGTDMETRKKD", "length": 263 }, "evidence": [ { "id": "MGI:1923195", "url": "https://alliancegenome.org/gene/MGI:1923195#orthology", "database": "AGR" }, { "id": "HGNC:26477", "url": "https://alliancegenome.org/gene/HGNC:26477#orthology", "database": "AGR" }, { "id": "SGD:S000003877", "url": "https://alliancegenome.org/gene/SGD:S000003877#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2B9S8-1", "protein_name": "TLC domain-containing protein 4 isoform X1", "gene_name": "tlcd4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEGMSVKHLLYFSPGAWGRVAMDPFSQLILLISVVSFFFFQWLFHSVSPWASSRISPGFLKLTHKQKIEWNSRTVSTLHALLVGLFCLYILFFDEAVNQDPVWGDPTLVKINVSITTGYLISDLLLIFYYWRAIGDKFFVIHHLAALYAYYYVLGQGMLPYFANFRLLAEFSTPCVNQRWFFEVLGYPKSSRPNMANGVLMAAVFFLVRIAVMPVYYSRMCSVYGTEAFYRVSFGGRSAWIFSSICLDIMNVMWMHKIFRGCYKVLQSSRKSKAESQENGKTD", "length": 284 }, "evidence": [ { "id": "MGI:1923195", "url": "https://alliancegenome.org/gene/MGI:1923195#orthology", "database": "AGR" }, { "id": "HGNC:26477", "url": "https://alliancegenome.org/gene/HGNC:26477#orthology", "database": "AGR" }, { "id": "SGD:S000003877", "url": "https://alliancegenome.org/gene/SGD:S000003877#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4AAE5-1", "protein_name": "TLC domain containing 4", "gene_name": "Tlcd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEANTNVVIGTVCCSFVTFQLLFHFISCWFSARVSLGYNSLSTEKKIEWNSRVVSTCHSMLVGIFGLYLFFFDEATIADPLWGDPSLVKINISTASGYLISDLLIILFNWKVIGDKFFIIHHCAGLIAYYFVLKIGVLAYIANFRLLAELSSPFVNQRWFFEVLKYPKFSKVNVINGILMTVVFFIVRIIAIPPMYFYVYSVYGTEPYIRLGSVVHFVWISSCIVLDVMNIMWMIKITKGCMKVISLIRQEKAKDSLQNGKLD", "length": 263 }, "evidence": [ { "id": "MGI:1923195", "url": "https://alliancegenome.org/gene/MGI:1923195#orthology", "database": "AGR" }, { "id": "HGNC:26477", "url": "https://alliancegenome.org/gene/HGNC:26477#orthology", "database": "AGR" }, { "id": "SGD:S000003877", "url": "https://alliancegenome.org/gene/SGD:S000003877#orthology", "database": "AGR" }, { "id": "SGD:S000006318", "url": "https://alliancegenome.org/gene/SGD:S000006318#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P47153-1", "protein_name": "Topoisomerase I damage affected protein 4", "gene_name": "TDA4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNANSTTTAIGLTSPFEKLSFFPHSSNLILAHLHEIIFSFVFYQLAFSVVAPFLNKVVFRKHYTTIRDPLLKIDFNVHTVSMIQAVVSNTVLLPTLTTPMHYNVVTYTDSYSSMVSSLSAGYFIWDLTMCVRYFKLYGLEFTGHAIGSVYVMLLSLRPFCQPWIGRFLIYEASTPFVNINWFIMQCNAKSKNSIPLWFNVVNGLLLMTVFFVVRICWGSIASALLFRQMWKVRDELPKFSAVTMMSLNIFMNLLNVLWFKKMIRIAKKLAKPAPTSKLD", "length": 279 }, "evidence": [ { "id": "MGI:1923195", "url": "https://alliancegenome.org/gene/MGI:1923195#orthology", "database": "AGR" }, { "id": "HGNC:26477", "url": "https://alliancegenome.org/gene/HGNC:26477#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-90#orthology", "database": "AGR" }, { "id": "SGD:S000003877", "url": "https://alliancegenome.org/gene/SGD:S000003877#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q06107-1", "protein_name": "Uncharacterized TLC domain-containing protein YPR114W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDVLLSLPQPELFKTTVIPFLANRNIIKSEAILSNLHSIFYVAIFYHIWFLFGKWILFPHLVKWKLDYDQKHNVKKDEKTTSERQAQHYKKKYTSLINQSSVHLISLLQSIVVLYYSLKFLLDPKASAEPYQTSHSRVFTENRDTQVICIFAIGYFVWDIYISTMYSTFPFVVHGIISTVVFCIGLKPYIQYYAPVFLMFELSNPSLNFRWFGIKFLPQKSKFCSLLLLLNNLTLMVVFFAARIAWGWFQIGKLCYDFYQVRNEPGFLVFDTIVILAGNFVLDILNVIWFSTMVSVAAKVLKKGESVDKVTKNEQ", "length": 315 }, "evidence": [ { "id": "MGI:1923195", "url": "https://alliancegenome.org/gene/MGI:1923195#orthology", "database": "AGR" }, { "id": "HGNC:26477", "url": "https://alliancegenome.org/gene/HGNC:26477#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-90#orthology", "database": "AGR" }, { "id": "SGD:S000006318", "url": "https://alliancegenome.org/gene/SGD:S000006318#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8CGF5-1", "protein_name": "TLC domain-containing protein 4", "gene_name": "Tlcd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEASTKAAVGSGAMEASTKAVICTVCSSFVVFQILFHFVSYWFSARVSSGYNSLSIDKKIEWNSRVVSTCHSLLVGIFGLYLFFFDEATITDPLWGDPTYVNINIATASGYLISDLLIILFNWKVIGDKFFIIHHCAGLTAYYFVLTTGALAYIANFRLLAELSSPFVNQRWFFEALKYPKFSKANVINGILMTVVFFIVRIISIPPMYFFLYSVYGTEPYIRFGFVIQSVWIVTCVILDVMNIMWMIKITKGCIKVISLIRQEKAKDSLQNGKLD", "length": 276 }, "evidence": [ { "id": "MGI:1923195", "url": "https://alliancegenome.org/gene/MGI:1923195#orthology", "database": "AGR" }, { "id": "HGNC:26477", "url": "https://alliancegenome.org/gene/HGNC:26477#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-90#orthology", "database": "AGR" }, { "id": "SGD:S000003877", "url": "https://alliancegenome.org/gene/SGD:S000003877#orthology", "database": "AGR" }, { "id": "SGD:S000006318", "url": "https://alliancegenome.org/gene/SGD:S000006318#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96MV1-1", "protein_name": "TLC domain-containing protein 4", "gene_name": "TLCD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEINTKLLISVTCISFFTFQLLFYFVSYWFSAKVSPGFNSLSFKKKIEWNSRVVSTCHSLVVGIFGLYIFLFDEATKADPLWGGPSLANVNIAIASGYLISDLSIIILYWKVIGDKFFIMHHCASLYAYYLVLKNGVLAYIGNFRLLAELSSPFVNQRWFFEALKYPKFSKAIVINGILMTVVFFIVRIASMLPHYGFMYSVYGTEPYIRLGVLIQLSWVISCVVLDVMNVMWMIKISKGCIKVISHIRQEKAKNSLQNGKLD", "length": 263 }, "evidence": [ { "id": "MGI:1923195", "url": "https://alliancegenome.org/gene/MGI:1923195#orthology", "database": "AGR" }, { "id": "HGNC:26477", "url": "https://alliancegenome.org/gene/HGNC:26477#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-90#orthology", "database": "AGR" }, { "id": "SGD:S000003877", "url": "https://alliancegenome.org/gene/SGD:S000003877#orthology", "database": "AGR" }, { "id": "SGD:S000006318", "url": "https://alliancegenome.org/gene/SGD:S000006318#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9V3S7-1", "protein_name": "TLC domain-containing protein", "gene_name": "Dmel\\CG17841", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQQRRQPANGNGRGGGTTAAVRTEEQQQQQQPLSQDAGAKEAGSTPGKATGRGCYFSLAFSIGSMGLACGSLWQIPNSSDRISLQRGLVLTSLGFIYFVSLTDFCNKYLLETTHGQRFRRKYRLMMSDVLEITNKIVSAIQASFSFFVGLIVCKSTCTKSFVYASHFLMEAYGWFGTAYFMYDIWSMYKVHTQKIADKLHLLRITKGQGAVVSNGHANGKVNGKSASGNNNGSTPTNLHEICDYDGACVQIPKDGRWDFLKYVVTHPVMMIHHVFIGTFGLLVVTYIRGGGHCIYSYMFMMEFSTPFVSLRSILSTMRLKDSRVYIANGLLMLATFFVCRVCMWPYVMWRYSLAIEAASLWSAMWGLPRGCLISIAILFLPQLYWFYLMVLGALKVFLPQKRRPPNAVLSAKSAAVPTPTPTALINGKN", "length": 429 }, "evidence": [ { "id": "SGD:S000003877", "url": "https://alliancegenome.org/gene/SGD:S000003877#orthology", "database": "AGR" }, { "id": "SGD:S000006318", "url": "https://alliancegenome.org/gene/SGD:S000006318#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", 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"table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5XIY6-1", "uniprot_ac": "Q5XIY6", "uniprot_id": "VTC1B_DANRE", "mass": { "chemical_mass": 43943.0, "monoisotopic_mass": 43943.0 }, "refseq": { "ac": "NP_001005772", "name": "V-type proton ATPase subunit C 1-B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772" }, "gene_names": [ { "name": "atp6v1c1b", "type": "recommended", "evidence": [ { "id": "Q5XIY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6" } ] }, { "name": "atp6v1c1b", "type": "synonym", "evidence": [ { "id": "NP_001005772", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772" } ] }, { "name": "atp6v1c1l", "type": "synonym", "evidence": [ { "id": "NP_001005772", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772" }, { "id": "Q5XIY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6" } ] }, { "name": "si:ch211-215i13.2", "type": "synonym", "evidence": [ { "id": "Q5XIY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6" } ] }, { "name": "si:zc215i13.2", "type": "synonym", "evidence": [ { "id": "NP_001005772", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772" } ] }, { "name": "zgc:92684", "type": "synonym", "evidence": [ { "id": "NP_001005772", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772" }, { "id": "Q5XIY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6" } ] } ], "protein_names": [ { "name": "V-type proton ATPase subunit C 1-B", "type": "recommended", "evidence": [ { "id": "Q5XIY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6/entry#names_and_taxonomy" } ] }, { "name": "ATPase, H+ transporting, lysosomal, V1 subunit C1b", "type": "synonym", "evidence": [ { "id": "NP_001005772", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772" } ] }, { "name": "V-ATPase subunit C 1-B", "type": "synonym", "evidence": [ { "id": "NP_001005772", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772" }, { "id": "Q5XIY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6/entry#names_and_taxonomy" } ] }, { "name": "V-type proton ATPase subunit C 1-B", "type": "synonym", "evidence": [ { "id": "NP_001005772", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772" } ] }, { "name": "Vacuolar proton pump subunit C 1-B", "type": "synonym", "evidence": [ { "id": "Q5XIY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6/entry#names_and_taxonomy" } ] }, { "name": "vacuolar proton pump subunit C 1-B", "type": "synonym", "evidence": [ { "id": "NP_001005772", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC083532.1, GFIL01001997.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000019.1. On Oct 5, 2007 this sequence version replaced NP_001005772.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001005772", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772" } ] }, { "annotation": "Subunit of the V1 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (By similarity). V-ATPase is responsible for acidifying and maintaining the pH of intracellular compartments and in some cell types, is targeted to the plasma membrane, where it promotes acidification of the extracellular environment (By similarity). The V-ATPase complex also acts as an activator for mTORC1 on lysosomal membrane by promoting the guanine nucleotide exchange factor (GEF) of the Ragulator complex, thereby enabling mTORC1 recruitment (By similarity). Subunit C is necessary for the assembly of the catalytic sector of the enzyme and is likely to have a specific function in its catalytic activity (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5XIY6", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6#function" }, { "database": "UniProtKB", "id": "P21282", "url": "https://www.uniprot.org/uniprotkb/P21282#function" }, { "database": "UniProtKB", "id": "P31412", "url": "https://www.uniprot.org/uniprotkb/P31412#function" }, { "database": "UniProtKB", "id": "P21283", "url": "https://www.uniprot.org/uniprotkb/P21283#function" } ] }, { "annotation": "This is the first report on the role of V-ATPase during adult vertebrate regeneration. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001005772", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772" }, { "database": "PubMed", "id": "24671205", "url": "https://glygen.org/publication/PubMed/24671205" } ] } ], "disease": [ { "disease_id": "DOID:0050866", "recommended_name": { "id": "DOID:0050866", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050866", "name": "oral squamous cell carcinoma", "description": "An oral cavity cancer that has_material_basis_in squamous cells." }, "synonyms": [ { "id": "DOID:0050866", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050866", "name": "mouth squamous cell carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050866", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050866" } ] }, { "disease_id": "DOID:162", "recommended_name": { "id": "DOID:162", "resource": "Disease Ontology", 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"evidence": [ { "id": "5517", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5517" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5XIY6", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "atp6v1c1b", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041010-104", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-104", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5XIY6", "url": "https://alphafold.ebi.ac.uk/entry/Q5XIY6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000035880", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000035880", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14785", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14785", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "449655", "url": "https://www.ncbi.nlm.nih.gov/gene/449655", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:449655", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449655", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VMIWIHV", "url": "https://omabrowser.org/oma/group/VMIWIHV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q5XIY6", "url": "https://www.orthodb.org/?gene=Q5XIY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10137", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10137", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10137:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10137:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03223", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03223", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5XIY6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5XIY6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001005772", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5XIY6", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5XIY6-1", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041010-104", "url": "https://zfin.org/ZDB-GENE-041010-104", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTEFWLISAPGDKTCQQTWDKMNMATAESNNLSTNNKFNIPELKVGTLDVLVGLSDELAKLDTFVESVVKKIAQYMTDVLEDSRDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKSISEIMSKQVTQIDNDLKARASAYNSLKGSLQSLERKNVGSLLTRSLADIVKKEDFVLDSEYLTTLLVIVSKTNYPEWQKTYETLSEMVVPRSTKLLFEDQESGLFSVTLFTKAIDDFKQQARENKFMVRDFLYNEEEMKADKEEMTRLSTDKKKQFGPLVRWLKVNFSETFIAWIHIKALRVFTESVLRYGLPVNFQAMLLQPNKKNVKKLREVLKDLYKHLDSSAAVIDGSVDIPGLNLSQQEYYPYVYYKIDVNLLELK", "length": 381, "header": "sp|Q5XIY6-1|VTC1B_DANRE Isoform 1 of V-type proton ATPase subunit C 1-B OS=Danio rerio OX=7955 GN=atp6v1c1b PE=2 SV=1 CANONICAL=Q5XIY6-1" }, "isoforms": [ { "isoform_ac": "Q5XIY6-1", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6/entry#Q5XIY6-1", "sequence": { "sequence": "MTEFWLISAPGDKTCQQTWDKMNMATAESNNLSTNNKFNIPELKVGTLDVLVGLSDELAKLDTFVESVVKKIAQYMTDVLEDSRDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKSISEIMSKQVTQIDNDLKARASAYNSLKGSLQSLERKNVGSLLTRSLADIVKKEDFVLDSEYLTTLLVIVSKTNYPEWQKTYETLSEMVVPRSTKLLFEDQESGLFSVTLFTKAIDDFKQQARENKFMVRDFLYNEEEMKADKEEMTRLSTDKKKQFGPLVRWLKVNFSETFIAWIHIKALRVFTESVLRYGLPVNFQAMLLQPNKKNVKKLREVLKDLYKHLDSSAAVIDGSVDIPGLNLSQQEYYPYVYYKIDVNLLELK", "length": 381, "header": "sp|Q5XIY6-1|VTC1B_DANRE Isoform 1 of V-type proton ATPase subunit C 1-B OS=Danio rerio OX=7955 GN=atp6v1c1b PE=2 SV=1 CANONICAL=Q5XIY6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "Q5XIY6", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] }, { "title": "V-ATPase proton pumping activity is required for adult zebrafish appendage regeneration.", "journal": "PloS one", "date": "2014", "authors": "Monteiro Joana, Aires Rita, Becker J\u00f6rg D, Jacinto Ant\u00f3nio, Certal Ana C, Rodr\u00edguez-Le\u00f3n Joaqu\u00edn", "evidence": [ { "database": "RefSeq", "id": "NP_001005772", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005772" } ], "reference": [ { "type": "PubMed", "id": "24671205", "url": "https://glygen.org/publication/PubMed/24671205" } ] } ], "pathway": [ { "id": "dre:449655", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449655", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9PF27-1", "protein_name": "V-type proton ATPase subunit C", "gene_name": "atp6v1c2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEFWLISVPLDKISCQSVEKLKRVAAKNGQSASSRMHIPELKVGTLDVLLGLSDDLSRLDSFTEGVMRQTSQCLAEVMDEFSGKLLESLLAGGEHRTLQKDPKSPLKSYFQTVQVDLATYVTRFQWDRAKYPTAQPLKTLADIISKQVSQVDTELKSRRASYSHLKASIQSYERKSEGSLQNRLLTNIVKKEDLVLNSEYLTTLIVLVPRTEYVLWQKTYESMSKFVVPRSSRKLAEDAEAGVFTVTLFKSVIAEFKANAKKHKFTVREYNLEEAEKQKQKIGRLALDKKELCRTFVCWLKVNFSETFVAWIHVKVLRTFVESVLRYGLPVSFQAILLQPGKKNVKHLKQQLNSLFKHLDPAAISTKPEMGLDIPDGGAGQQEYYSYICYPIKINLVDPS", "length": 400 }, "evidence": [ { "id": "FB:FBgn0287825", "url": "https://alliancegenome.org/gene/FB:FBgn0287825#orthology", "database": "AGR" }, { "id": "SGD:S000001563", "url": "https://alliancegenome.org/gene/SGD:S000001563#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P21282-1", "protein_name": "V-type proton ATPase subunit C 1", "gene_name": "ATP6V1C1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTEFWLISAPGEKTCQQTWEKLHAATTKNNNLAVSSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHKARENKFIVRDFQYNEEEMKADKEEMNRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHVKALRVFVESVLRYGLPVNFQAMLLQPNKKTMKKLREVLYELYKHLDSSAAAIIDAPMDIPGLNLSQQEYYPYVYYKIDCNLLEFK", "length": 382 }, "evidence": [ { "id": "Q5XIY6", "url": "https://omabrowser.org/oma/group/Q5XIY6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P21283-1", "protein_name": "V-type proton ATPase subunit C 1", "gene_name": "ATP6V1C1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEFWLISAPGEKTCQQTWEKLHAATSKNNNLAVTSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGVVKKVAQYMADVLEDSKDKVQENLLANGVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHKARENKFIVRDFQYNEEEMKADKEEMNRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHVKALRVFVESVLRYGLPVNFQAMLLQPNKKTLKKLREVLHELYKHLDSSAAAIIDAPMDIPGLNLSQQEYYPYVYYKIDCNLLEFK", "length": 382 }, "evidence": [ { "id": "RGD:1311082", "url": "https://alliancegenome.org/gene/RGD:1311082#orthology", "database": "AGR" }, { "id": "MGI:1913585", "url": "https://alliancegenome.org/gene/MGI:1913585#orthology", "database": "AGR" }, { "id": "HGNC:856", "url": "https://alliancegenome.org/gene/HGNC:856#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-104", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-104#orthology", "database": "AGR" }, { "id": "FB:FBgn0287825", "url": "https://alliancegenome.org/gene/FB:FBgn0287825#orthology", "database": "AGR" }, { "id": "SGD:S000001563", "url": "https://alliancegenome.org/gene/SGD:S000001563#orthology", "database": "AGR" }, { "id": "Q5XIY6", "url": "https://omabrowser.org/oma/group/Q5XIY6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P31412-1", "protein_name": "V-type proton ATPase subunit C", "gene_name": "VMA5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MATALYTANDFILISLPQNAQPVTAPGSKTDSWFNETLIGGRAFVSDFKIPEFKIGSLDTLIVESEELSKVDNQIGASIGKIIEILQGLNETSTNAYRTLPINNMPVPEYLENFQWQTRKFKLDKSIKDLITLISNESSQLDADVRATYANYNSAKTNLAAAERKKTGDLSVRSLHDIVKPEDFVLNSEHLTTVLVAVPKSLKSDFEKSYETLSKNVVPASASVIAEDAEYVLFNVHLFKKNVQEFTTAAREKKFIPREFNYSEELIDQLKKEHDSAASLEQSLRVQLVRLAKTAYVDVFINWFHIKALRVYVESVLRYGLPPHFNIKIIAVPPKNLSKCKSELIDAFGFLGGNAFMKDKKGKINKQDTSLHQYASLVDTEYEPFVMYIINL", "length": 392 }, "evidence": [ { "id": "RGD:1311082", "url": "https://alliancegenome.org/gene/RGD:1311082#orthology", "database": "AGR" }, { "id": "MGI:1913585", "url": "https://alliancegenome.org/gene/MGI:1913585#orthology", "database": "AGR" }, { "id": "HGNC:856", "url": "https://alliancegenome.org/gene/HGNC:856#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-104", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-104#orthology", "database": "AGR" }, { "id": "FB:FBgn0287825", "url": "https://alliancegenome.org/gene/FB:FBgn0287825#orthology", "database": "AGR" }, { "id": "SGD:S000001563", "url": "https://alliancegenome.org/gene/SGD:S000001563#orthology", "database": "AGR" }, { "id": "Q5XIY6", "url": "https://omabrowser.org/oma/group/Q5XIY6/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P54648-1", "protein_name": "V-type proton ATPase subunit C", "gene_name": "vatC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSETQEFWLISAPNLPGADIFDQVNQKTAKENSLSENKKFNTPALRVGTLNSLITLNDELQKIDTIVESTTKKIARQLVDLVGTKPGKDKSLSINGHTIPQYLQQFAWDDAKYNLKLSLQEIVEKISSAVSKIDDDLKIKSSEYSTLSSSVASEERKASGNLQVRTLNDLITADNIVQTDYFTTAFVVIPKQSEKEFLACYETISDFVLGRSAKRVAQDNDYFLYSVILFKKFYENFKTKIIEKKWVVRDFKLEDNKPTQERSKLTEDKKNCRTSLIRWCRLNFPEAFMAWVHLKVVRVFVESVLRFGIPFNFQAILMKPQKGADKKVRDILFDQFKYLGSAHISGKNETDDSEKFYPYISVSVNWEN", "length": 368 }, "evidence": [ { "id": "Q5XIY6", "url": "https://omabrowser.org/oma/group/Q5XIY6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5FVI6-1", "protein_name": "V-type proton ATPase subunit C 1", "gene_name": "Atp6v1c1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEFWLISAPGEKTCQQTWEKLHAATTKNNNLAVSSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGVVKKVAQYMADVLEDSKDKVQENLLASGVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFKKAVDDFRHKARENKFIVRDFQYNEEEMRADKEEMNRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAMLLQPNKKSVKKLREVLHELYKHLDSSAAAIIDAPMDIPGLNLSQQEYYPYVYYKIDCNLLEFK", "length": 382 }, "evidence": [ { "id": "RGD:1311082", "url": "https://alliancegenome.org/gene/RGD:1311082#orthology", "database": "AGR" }, { "id": "MGI:1913585", "url": "https://alliancegenome.org/gene/MGI:1913585#orthology", "database": "AGR" }, { "id": "HGNC:856", "url": "https://alliancegenome.org/gene/HGNC:856#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-104", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-104#orthology", "database": "AGR" }, { "id": "FB:FBgn0287825", "url": "https://alliancegenome.org/gene/FB:FBgn0287825#orthology", "database": "AGR" }, { "id": "SGD:S000001563", "url": "https://alliancegenome.org/gene/SGD:S000001563#orthology", "database": "AGR" }, { "id": "Q5XIY6", "url": "https://omabrowser.org/oma/group/Q5XIY6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AYE4-1", "protein_name": "V-type proton ATPase subunit C 2", "gene_name": "Atp6v1c2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEFWLISAPGDKENLQALERMNSVTSKSNLSHNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAESLIKRMAQSVVEVMEDSKGKVHENLLANGVDLTSFVTHFEWDMAKYPAKQPLVSVVDTLAKQLAQIETDLKSRTAAYSVLKANLENLEKKSTGNLFTRTLSDIVSKEDFVLDSEYLITLLVIVPKSSYVQWQKTYESLSDMVVPRSTKLIAEDNEGGLFTVTLFRKVIEDFKVKAKENKFIVREFYYDEKEIKREREEMTRLLSDKKQQYQTSCVALKKGSATYRDHKVKVTPLGNPTRPTAGQNDRESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSATKRLREVLNSVFRHLDEVAAASILDASVEIPGLQLSNQDYFPYVYFHIDLSLLD", "length": 425 }, "evidence": [ { "id": "FB:FBgn0287825", "url": "https://alliancegenome.org/gene/FB:FBgn0287825#orthology", "database": "AGR" }, { "id": "SGD:S000001563", "url": "https://alliancegenome.org/gene/SGD:S000001563#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7T385-1", "protein_name": "V-type proton ATPase subunit C 1-A", "gene_name": "atp6v1c1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTEFWLISAPGEKTCQQTWDKLMTATTRTNNLSTNNKFNIPDLKVGTLDVLVGLSDELAKLDAFVESVVKKVAQYMADVLEDSRDKVQENLLANGVDLVTYVTRFQWDMAKYPIKQSLKNISEIISKQVSQIDNDLKARASAYNNLKGNLQNLERKNAGSLLTRSLADIVKKDDFVLDSEYLITLLVVVPKTNYTDWQRTYETLAEMVVPRSTNLLFEDHDSGLFTVTLFRKAIDDFRHKARENKFTVRDFQYNEEEMKADKEEMTRLSTDKKKQFGPLVRWLKVNFSEAFIAWVHIKALRVFVESVLRYGLPVNFQAMLLQPNKKNMKKLREVLYDLYKHLDSSAAAIIDQSAMDIPGLNLSQQEYYPYVYYKIDCNLLDFK", "length": 383 }, "evidence": [ { "id": "RGD:1311082", "url": "https://alliancegenome.org/gene/RGD:1311082#orthology", "database": "AGR" }, { "id": "MGI:1913585", "url": "https://alliancegenome.org/gene/MGI:1913585#orthology", "database": "AGR" }, { "id": "HGNC:856", "url": "https://alliancegenome.org/gene/HGNC:856#orthology", "database": "AGR" }, { "id": "FB:FBgn0287825", "url": "https://alliancegenome.org/gene/FB:FBgn0287825#orthology", "database": "AGR" }, { "id": "SGD:S000001563", "url": "https://alliancegenome.org/gene/SGD:S000001563#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8NEY4-1", "protein_name": "V-type proton ATPase subunit C 2", "gene_name": "ATP6V1C2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEFWLISAPGDKENLQALERMNTVTSKSNLSYNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAESLIRRMAQSVVEVMEDSKGKVQEHLLANGVDLTSFVTHFEWDMAKYPVKQPLVSVVDTIAKQLAQIEMDLKSRTAAYNTLKTNLENLEKKSMGNLFTRTLSDIVSKEDFVLDSEYLVTLLVIVPKPNYSQWQKTYESLSDMVVPRSTKLITEDKEGGLFTVTLFRKVIEDFKTKAKENKFTVREFYYDEKEIEREREEMARLLSDKKQQYQTSCVALKKGSSTFPDHKVKVTPLGNPDRPAAGQTDRERESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSSTKRLREVLNSVFRHLDEVAATSILDASVEIPGLQLNNQDYFPYVYFHIDLSLLD", "length": 427 }, "evidence": [ { "id": "FB:FBgn0287825", "url": "https://alliancegenome.org/gene/FB:FBgn0287825#orthology", "database": "AGR" }, { "id": "SGD:S000001563", "url": "https://alliancegenome.org/gene/SGD:S000001563#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99L60-1", "protein_name": "V-type proton ATPase subunit C 2", "gene_name": "Atp6v1c2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEFWLISAPGDKENLQALERMNNVTSKSNLSHNTKFAIPDFKVGTLDSLVGLSDELGKLDTFAESLIKRMAQSVVEVMEDSKGKAHETLLANGVDLTSFVTHFEWDMAKYPAKQPLVSVVDTLAKQLAQIETDLKSRTAAYSVLKANLENLEKRSTGNLFTRTLSDIVSKEDFVLDSEYLITLLVIVPKSSFAQWQKTYESLSDMVVPRSTKLIAEDNEGGLFTVTLFRKVIEDFKVKAKENKFIVREFYYDEKEIKREREEMTRLLSDKKQQYPTSCVALKKGSATYRDHKVKVAPLGNPARPAAGQTDRDRESEGEGEGPLLRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAVLLQPHKKSATKRLREVLNSVFRHLDEVAAASILDASVEIPGLQLSNQDYFPYVYFHIDLSLLD", "length": 427 }, "evidence": [ { "id": "FB:FBgn0287825", "url": "https://alliancegenome.org/gene/FB:FBgn0287825#orthology", "database": "AGR" }, { "id": "SGD:S000001563", "url": "https://alliancegenome.org/gene/SGD:S000001563#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SDS7-1", "protein_name": "V-type proton ATPase subunit C", "gene_name": "VHA-C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MTSRYWVVSLPVKDSASSLWNRLQEQISKHSFDTPVYRFNIPNLRVGTLDSLLALGDDLLKSNSFVEGVSQKIRRQIEELERISGVESNALTVDGVPVDSYLTRFVWDEAKYPTMSPLKEVVDNIQSQVAKIEDDLKVRVAEYNNIRGQLNAINRKQSGSLAVRDLSNLVKPEDIVESEHLVTLLAVVPKYSQKDWLACYETLTDYVVPRSSKKLFEDNEYALYTVTLFTRVADNFRIAAREKGFQVRDFEQSVEAQETRKQELAKLVQDQESLRSSLLQWCYTSYGEVFSSWMHFCAVRTFAESIMRYGLPPAFLACVLSPAVKSEKKVRSILERLCDSTNSLYWKSEEDAGAMAGLAGDSETHPYVSFTINLA", "length": 375 }, "evidence": [ { "id": "Q5XIY6", "url": "https://omabrowser.org/oma/group/Q5XIY6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9V7N5-1", "protein_name": "V-type proton ATPase subunit C", "gene_name": "Vha44", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMSEYWIISAPGDKTCQQTYDTMNNLTSKQHNLCNNYKFHIPDLKVGTLDQLVGLSDDLGKLDTYVEQITRKVANYLGEVLEDQRDKLHENLMANNSPGPPDDSMPCRHHQRIKHLSLRHQRKHQHTHHQNKPQHYHHHHHHHQLPQDLKGKSAATCSPATPPAPASAPPHLPPACACDVLAPGSLTGGSLTNLSTSHEPEPEFDVCPCDECFACAPPSTSATASTLLADECYSQTASSMLSATRCALSTVAAIATGSGLGNGPSTSAAAAAAASNSSGGGGGGGPASCSTLCSSAYFSTSAPTTSSSVHSSMSRSNSKRLNNNTCSINNNKLSFRSGSHVSQLHLATQQPQHHHSHPHQQPHTNPLQSPVQKSMSEDEGDASNAHEDGETDEDPKSPHSVQSDLSDAFDWWFNKPKRNSKKSSAQQQHETAQLQHQQTTQQHATPLTPQNHNQYQNQHLSKAMTFWHQASTTPRSSYRSFFNSLADQIYSKRSTPSQLNINNGFNLTPTHRSSPVSSCCGSSSQGRSSPDTDPAEPPEFPLSPAELPQYLTRFQWDMAKYPIKQSLRNIADIISKQIGQIDGDLKTKSQAYNNLKGNLQNLEKKKTGSLLTRNLADLVKKEHFILDSEYLTTLLVIVPKVMANDWLTNYEKITDMIVPRSSQLIQEDADYCLFNVTLFKKVAEEFKLHARERKFIVRDFVYNEEELAAGKNEMTKLMTDKKKQFGPLVRWLKVNFSEAFCALIHVKALRVFVESVLRYGLPVNFQAILIEPNKKSVKRLRDVLNQLYGHLDGASAGGAVSSADNVDIPGLGFGQSEYFPYVFYKVNIDMVEQAKV", "length": 836 }, "evidence": [ { "id": "RGD:1311082", "url": "https://alliancegenome.org/gene/RGD:1311082#orthology", "database": "AGR" }, { "id": "MGI:1913585", "url": "https://alliancegenome.org/gene/MGI:1913585#orthology", "database": "AGR" }, { "id": "HGNC:856", "url": "https://alliancegenome.org/gene/HGNC:856#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-104", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-104#orthology", "database": "AGR" }, { "id": "FB:FBgn0287825", "url": "https://alliancegenome.org/gene/FB:FBgn0287825#orthology", "database": "AGR" }, { "id": "SGD:S000001563", "url": "https://alliancegenome.org/gene/SGD:S000001563#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z1G3-1", "protein_name": "V-type proton ATPase subunit C 1", "gene_name": "Atp6v1c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEFWLISAPGEKTCQQTWEKLHAATTKNNNLAVSSKFNIPDLKVGTLDVLVGLSDELAKLDAFVEGVVKKVAQYMADVLEDSKDKVQENLLASGVDLVTYITRFQWDMAKYPIKQSLKNISEIIAKGVTQIDNDLKSRASAYNNLKGNLQNLERKNAGSLLTRSLAEIVKKDDFVLDSEYLVTLLVVVPKLNHNDWIKQYETLAEMVVPRSSNVLSEDQDSYLCNVTLFRKAVDDFRHKARENKFIVRDFQYNEEEMKADKEEMTRLSTDKKKQFGPLVRWLKVNFSEAFIAWIHIKALRVFVESVLRYGLPVNFQAMLLQPNKKSVKKLREVLHELYKHLDSSAAAIIDAPMDIPGLNLSQQEYYPYVYYKIDCNLLEFK", "length": 382 }, "evidence": [ { "id": "RGD:1311082", "url": "https://alliancegenome.org/gene/RGD:1311082#orthology", "database": "AGR" }, { "id": "MGI:1913585", "url": "https://alliancegenome.org/gene/MGI:1913585#orthology", "database": "AGR" }, { "id": "HGNC:856", "url": "https://alliancegenome.org/gene/HGNC:856#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-104", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-104#orthology", "database": "AGR" }, { "id": "FB:FBgn0287825", "url": "https://alliancegenome.org/gene/FB:FBgn0287825#orthology", "database": "AGR" }, { "id": "SGD:S000001563", "url": "https://alliancegenome.org/gene/SGD:S000001563#orthology", "database": "AGR" }, { "id": "Q5XIY6", "url": "https://omabrowser.org/oma/group/Q5XIY6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "proton-transporting ATPase activity, rotational mechanism", "id": "GO:0046961", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046961", "evidence": [ { "database": "UniProtKB", "id": "Q5XIY6", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "vacuolar proton-transporting V-type ATPase, V1 domain", "id": "GO:0000221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000221", "evidence": [ { "database": "UniProtKB", "id": "Q5XIY6", "url": "https://www.uniprot.org/uniprotkb/Q5XIY6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 286, "end_pos": 288 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 359, "end_pos": 361 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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] }, { "uniprot_canonical_ac": "Q5XJA2-1", "uniprot_ac": "Q5XJA2", "uniprot_id": "C149A_DANRE", "mass": { "chemical_mass": 50106.0, "monoisotopic_mass": 50106.0 }, "refseq": {}, "gene_names": [ { "name": "ccdc149a", "type": "recommended", "evidence": [ { "id": "Q5XJA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XJA2" } ] }, { "name": "ccdc149b", "type": "synonym", "evidence": [ { "id": "Q5XJA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XJA2" } ] }, { "name": "zgc:103485", "type": "synonym", "evidence": [ { "id": "Q5XJA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XJA2" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 149-A", "type": "recommended", "evidence": [ { "id": "Q5XJA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XJA2/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5XJA2", "url": "https://www.uniprot.org/uniprotkb/Q5XJA2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ccdc149a", "url": "https://www.uniprot.org/uniprotkb/Q5XJA2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041010-113", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-113", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5XJA2", "url": "https://alphafold.ebi.ac.uk/entry/Q5XJA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "449999", "url": "https://www.ncbi.nlm.nih.gov/gene/449999", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:449999", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449999", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5XJA2", "url": "https://www.orthodb.org/?gene=Q5XJA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21682", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21682", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21682:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21682:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5XJA2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5XJA2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0AB13A9Y6", "url": "https://www.uniprot.org/uniprotkb/A0AB13A9Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13A9Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0AB13A9Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5XJA2", "url": "https://www.uniprot.org/uniprotkb/Q5XJA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5XJA2-1", "url": "https://www.uniprot.org/uniprotkb/Q5XJA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041010-113", "url": "https://zfin.org/ZDB-GENE-041010-113", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MANQLRETHQSLKKKYRELIDGESSLPPEKRNQVNLAQLLMDSRERNKQLAEEVKEVTQRLSETQGDNKLLRMTITKQRLGDDEVGIRHFPAHEREDLVRQLEKAALHREELEHTLKTLSDELQDVKAERTVFKEKSKRLNLELNHILGGQEKRIIDVDALCMENKYLHERLKQVQEEVSLLKSNIQKYKTALDRRKNPEIGGKSSSRSLTGVLSPKQVHGFLSEENGCSLPATPQSISDLKSLATALLETIHEKNIIIQHQRQTNRILGNRVADLERKLKTLEISGLWSLPDDRTGRGGPSLWERDTAGDDSFPNMWRGSRPGPDGGAGEEDTPVTREESDPSGTRTNGQVGTQLKEKKTACCPVTEVIAAVEELCVVLEAEDAVLALDPAGLQLQWTQTPSVTLEQSACKNTDIKNSAGSPATDLGEISEGAAVKIEPIEESGSSFVS", "length": 450, "header": "sp|Q5XJA2-1|C149A_DANRE Isoform 1 of Coiled-coil domain-containing protein 149-A OS=Danio rerio OX=7955 GN=ccdc149a PE=2 SV=1 CANONICAL=Q5XJA2-1" }, "isoforms": [ { "isoform_ac": "A0AB13A9Y6-1", "url": "https://www.uniprot.org/uniprotkb/Q5XJA2/entry#A0AB13A9Y6-1", "sequence": { "sequence": "MNSSKRSESDWQGLVSEFLICKRKLESKKDALLILSKELDTCQQERDQYKLMANQLRETHQSLKKKYRELIDGESSLPPEKRNQVNLAQLLMDSRERNKQLAEEVKEVTQRLSETQGDNKLLRMTITKQRLGDDEVGIRHFPAHEREDLVRQLEKAALHREELEHTLKTLSDELQDVKAERTVFKEKSERLNLELNHILGGQEKRIIDVDALCMENKYLHERLKQVQEEVSLLKSNIQKYKTALDRRKNPEIGGKSSSRSLTGVLSPKQVHGFLSEENGCSLPATPQSISDLKSLATALLETIHEKNIIIQHQRQTNRILGNRVADLERKLKTLEISGLWSLPGSRDAITLSPALLSSTDQSEALIFSTNSADDRTGRGGPSLWERDTAGDDSFPNMWRGSRPGPDGGAEEEDTPVTREESDPSGTRTNGQVGTQLKEKKTAFFPVTEEIAAVEELCVVLEAEDAVLALDPAGLQLQWTQTPSVTLKQSACKNTDIKNTAGSPATDLGEISEGAAVKKEPIEESGSSFVS", "length": 530, "header": "tr|A0AB13A9Y6-1|C149A_DANRE Computationally mapped isoform of Coiled-coil domain-containing protein 149-A OS=Danio rerio OX=7955 GN=ccdc149a PE=2 SV=1 CANONICAL=Q5XJA2-1" }, "locus": {} }, { "isoform_ac": "Q5XJA2-1", "url": "https://www.uniprot.org/uniprotkb/Q5XJA2/entry#Q5XJA2-1", "sequence": { "sequence": "MANQLRETHQSLKKKYRELIDGESSLPPEKRNQVNLAQLLMDSRERNKQLAEEVKEVTQRLSETQGDNKLLRMTITKQRLGDDEVGIRHFPAHEREDLVRQLEKAALHREELEHTLKTLSDELQDVKAERTVFKEKSKRLNLELNHILGGQEKRIIDVDALCMENKYLHERLKQVQEEVSLLKSNIQKYKTALDRRKNPEIGGKSSSRSLTGVLSPKQVHGFLSEENGCSLPATPQSISDLKSLATALLETIHEKNIIIQHQRQTNRILGNRVADLERKLKTLEISGLWSLPDDRTGRGGPSLWERDTAGDDSFPNMWRGSRPGPDGGAGEEDTPVTREESDPSGTRTNGQVGTQLKEKKTACCPVTEVIAAVEELCVVLEAEDAVLALDPAGLQLQWTQTPSVTLEQSACKNTDIKNSAGSPATDLGEISEGAAVKIEPIEESGSSFVS", "length": 450, "header": "sp|Q5XJA2-1|C149A_DANRE Isoform 1 of Coiled-coil domain-containing protein 149-A OS=Danio rerio OX=7955 GN=ccdc149a PE=2 SV=1 CANONICAL=Q5XJA2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Comparative evolutionary genomics of medaka and three-spined stickleback fabp2a and fabp2b genes with fabp2 of zebrafish.", "journal": "Genome", "date": "2013", "authors": "Parmar Manoj B, Wright Jonathan M", "evidence": [ { "database": "UniProtKB", "id": "A0AB13A9Y6", "url": "https://www.uniprot.org/uniprotkb/A0AB13A9Y6" } ], "reference": [ { "type": "PubMed", "id": "23379336", "url": "https://glygen.org/publication/PubMed/23379336" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0AB13A9Y6", "url": "https://www.uniprot.org/uniprotkb/A0AB13A9Y6" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:449999", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449999", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ARX4-1", "protein_name": "Coiled-coil domain containing 149", "gene_name": "Ccdc149", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMRFSSRENDCNDHDWLESWQMVARALLTWVIKAYLVCKRKLESKKEALLILSKELDTCQQERDQYKLMANQLRERHQSLKKKYRELIDGDPSLPPEKRKQANLAQLLRESQDRNKHLGEEIKELRQRLGEVQGDNKLLRMTIAKQRLGDEEIGVRHFAAHEREDLVEQLERAKEQIESLEHDLQASVDELQDVKEERASYQDKVDRLNQELNHILGGHENRIIDVDALCMENRYLQERLKQLHEEVSLLKSNIAKYKNALERRKNSKTQGKSNSSALTGVLSAKQVQDLLSEDHGCSLPATPQSIADLKSLATALLETIHEKNMVIQHQRQTNRILGNRVAELEKKLRTLEVSGLWSLPGGKDTILLSDQTLPTIQKSKSPLLKFVEQPTESKESARDGEIQTQERDESRAAAEALTVPEDAGRPAVSSPAPPSNANQHSDFHHPPVPQPLSEEVNTVGGREITQLTDGQEATDLEEVPREAPTEEQRCEPQPSPSSLSQEECIVTLQDHLPSMQPEVKATSTGGDRGISEGGDTRSTVQT", "length": 543 }, "evidence": [ { "id": "HGNC:25405", "url": "https://alliancegenome.org/gene/HGNC:25405#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-113", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-113#orthology", "database": "AGR" }, { "id": "MGI:2685293", "url": "https://alliancegenome.org/gene/MGI:2685293#orthology", "database": "AGR" }, { "id": "RGD:1582968", "url": "https://alliancegenome.org/gene/RGD:1582968#orthology", "database": "AGR" }, { "id": "FB:FBgn0038330", "url": "https://alliancegenome.org/gene/FB:FBgn0038330#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6V035-1", "protein_name": "Coiled-coil domain containing 149", "gene_name": "Ccdc149", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGDRTESDWQGLVSEYLVCKRKLESKKEALLILSKELDTCQQERDQYKLMANQLRERHQSLKKKYRELIDGDPSLPPEKRKQANLAQLLRESQDRTKHLGEEIKELRQRLGEVQGDNKLLRMTIAKQRLGDEEIGMRHFAAHEREDLVEQLERAKEQIESLEHDLQASADELQDVKEERASYQDKVDRLNQELNHILGGHENRIIDVDALCMENRYLQERLKQLHEEVSLLKSNIAKYKNALERRKNSKSQGKSSSSALTGVLSAKQVQDLLSEDHGCSLPATPQSIADLKSLATALLETIHEKNMVIQHQRQTNRILGNRVAELEKKLRTLEVSGLWSLPGGKDTILLNDQTLPTIQRSKSPLLKFVEQSTDNKESARDGEIQKQEDESCAAAEALAEPEDAGKPAVSSTAPLSHANQQHLDFHHPPVPQPPSEEVNTVGRESIQLTDGQQAADLEEVPREAPTEEQKCEPGLPPSSLASQEECTTTFQDHLPSTQPEVKASSVGGNRGISEGGDTRSTVHT", "length": 524 }, "evidence": [ { "id": "HGNC:25405", "url": "https://alliancegenome.org/gene/HGNC:25405#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-113", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-113#orthology", "database": "AGR" }, { "id": "MGI:2685293", "url": "https://alliancegenome.org/gene/MGI:2685293#orthology", "database": "AGR" }, { "id": "RGD:1582968", "url": "https://alliancegenome.org/gene/RGD:1582968#orthology", "database": "AGR" }, { "id": "FB:FBgn0038330", "url": "https://alliancegenome.org/gene/FB:FBgn0038330#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6DH86-1", "protein_name": "Coiled-coil domain-containing protein 149-B", "gene_name": "ccdc149b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANQLRERHQGLKKKYRELIDGDPSLPPEKRNQVNLAQLLRDSREHNKQLSEELKELKQRLAEVHGDNKLLRMTIAKQRLGDEEVGTRHFPAHEREDLVQQLERAREQTEALEQSLKAATDELQDVRAERNVYQEKAHRLNLEINHILGSHENRILDIDALCMENRYLHERLMQLQEEVSLLKSNVMKYKSALESKKNCKVYGKSNSSALTGVLSAKQVQELLLSEENGCSLPVTSQSISDLKSLATALLETIHEKNMVIRHQRQTNKILGNRVAELERKLKTLEVSGLWSLPGITYNVSLGLGRRKAVIVLSDSQHVQSTTEQSVHLTPEAMVADEEIVTGEEVTEDTGLSADFSQDECQAGAVELNQNSDYFTHTYSVSATPQVSTPAENIQPVESMQSKTLALCDSERSACTAERSEQHDEDLQSGGHQSMSTEASLKALEEQAVENDNFSGDCESQGALEDSQPVTSETSGSFDCISGSESCTAEQQTERSIEEETEHASLNTSPPEQTSPHQECPSS", "length": 522 }, "evidence": [ { "id": "HGNC:25405", "url": "https://alliancegenome.org/gene/HGNC:25405#orthology", "database": "AGR" }, { "id": "MGI:2685293", "url": "https://alliancegenome.org/gene/MGI:2685293#orthology", "database": "AGR" }, { "id": "RGD:1582968", "url": "https://alliancegenome.org/gene/RGD:1582968#orthology", "database": "AGR" }, { "id": "FB:FBgn0038330", "url": "https://alliancegenome.org/gene/FB:FBgn0038330#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZUS6-1", "protein_name": "Coiled-coil domain-containing protein 149", "gene_name": "CCDC149", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANQLRERHQSLKKKYRELIDGDPSLPPEKRKQANLAQLLRDSQDRNKHLGEEIKELQQRLGEVQGDNKLLRMTIAKQRLGDEAIGVRHFAAHEREDLVQQLERAKEQIESLEHDLQASVDELQDVKEERSSYQDKVERLNQELNHILSGHENRIIDVDALCMENRYLQERLKQLHEEVNLLKSNIAKYKNALERRKNSKGQGKSSSSALTGVLSAKQVQDLLSEDHGCSLPATPQSISDLKSLATALLETIHEKNMVIQHQRQTNKILGNRVAELEKKLRTLEVSGLWSLPGGKDTILFSDPTLPSGQRSRSPLLKFVEQPTENKADPKDGEAQKQEEDESCAAAEALTAPEDAGRPAVNSPANQSRGNQCKLFHPSLPQLPSEEEVNSLGREIIKLTKEQAAAELEEVRRESPIEGQRSETGPAPPGLAIQGELPKSHLDSFEASRPAAKASTPEDGKGIPEGGGMRSTVKT", "length": 474 }, "evidence": [ { "id": "HGNC:25405", "url": "https://alliancegenome.org/gene/HGNC:25405#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-113", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-113#orthology", "database": "AGR" }, { "id": "MGI:2685293", "url": "https://alliancegenome.org/gene/MGI:2685293#orthology", "database": "AGR" }, { "id": "RGD:1582968", "url": "https://alliancegenome.org/gene/RGD:1582968#orthology", "database": "AGR" }, { "id": "FB:FBgn0038330", "url": "https://alliancegenome.org/gene/FB:FBgn0038330#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VF72-1", "protein_name": "Coiled-coil domain-containing protein 149", "gene_name": "Dmel\\CG14868", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLDDVASHHGFGQHMATYNVETSAVHRKLQSKVEALRILRQELEQFRVERDQYKLVAETLQLRYSALKSNSELLAVGGCGALSENSSLAALLHETREQNLKLSTEVEALRQRLNELHGDMELLRETEASNKSRVQAMASENAARNKEELQWRRERANFICHLEGLKKRNAQLAFDLKAVIDEKEELITERDAYKCKAHRLNHELFVALRAKKTHPRLLDIDGVLLENKYLHERVKIQDSELELTKQSINKYKTMLDAKRKKGIVKLGGGSTNEDTILSPRQVKTILESGIELPQKTESLSDLKSLCLALLDNLNDKNLALTHQKKTNKILAGKMTELEQRWQQLLSGNDDNAEEQEEDVEYGYAPSQLLLNGYCAAMVDDADISSTPSIEPDNEGVAITADHEDSKKHKSVEALHSDDGMSSLSTESVDSSVYGADVQPDDFQKSSSATTDSGNCGLSSRCNGTPRISSAVARERMEDLKDLPPHLATLVQKALHDLDMRDYEAMVTIRAENLAAIP", "length": 518 }, "evidence": [ { "id": "HGNC:25405", "url": "https://alliancegenome.org/gene/HGNC:25405#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-113", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-113#orthology", "database": "AGR" }, { "id": "MGI:2685293", "url": "https://alliancegenome.org/gene/MGI:2685293#orthology", "database": "AGR" }, { "id": "RGD:1582968", "url": "https://alliancegenome.org/gene/RGD:1582968#orthology", "database": "AGR" }, { "id": "FB:FBgn0038330", "url": "https://alliancegenome.org/gene/FB:FBgn0038330#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q5XJN6-1", "uniprot_ac": "Q5XJN6", "uniprot_id": "CF263_DANRE", "mass": { "chemical_mass": 41867.0, "monoisotopic_mass": 41867.0 }, "refseq": { "ac": "NP_001006061", "name": "cilia- and flagella-associated protein 263", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006061" }, "gene_names": [ { "name": "cfap263", "type": "recommended", "evidence": [ { "id": "Q5XJN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6" } ] }, { "name": "ccdc113", "type": "synonym", "evidence": [ { "id": "NP_001006061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006061" }, { "id": "Q5XJN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6" } ] }, { "name": "cfap263", "type": "synonym", "evidence": [ { "id": "NP_001006061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006061" } ] }, { "name": "zgc:101745", "type": "synonym", "evidence": [ { "id": "NP_001006061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006061" }, { "id": "Q5XJN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6" } ] } ], "protein_names": [ { "name": "Cilia- and flagella-associated protein 263", "type": "recommended", "evidence": [ { "id": "Q5XJN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 263", "type": "synonym", "evidence": [ { "id": "NP_001006061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006061" } ] }, { "name": "coiled-coil domain containing 113", "type": "synonym", "evidence": [ { "id": "NP_001006061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006061" } ] }, { "name": "coiled-coil domain-containing protein 113", "type": "synonym", "evidence": [ { "id": "NP_001006061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006061" } ] }, { "name": "zgc:101745 ccdc113", "type": "synonym", "evidence": [ { "id": "NP_001006061", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006061" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC083263.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN06350654 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC083263.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001006061", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006061" } ] }, { "annotation": "Component of centriolar satellites contributing to primary cilium formation (By similarity). In complex with CFAP263, acts as a regulator of ciliary beating that connects radial spoke 3 (RS3) to the inner dynein arm (IDA) and the nexin-dynein regulatory complex (N-DRC). The complex is positioned parallel to N-DRC and forms a connection between the arch at the base of RS3, the IDA tail and N-DRC (By similarity).", "evidence": [ { "database": "UniProtKB", "id": "Q5XJN6", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6#function" }, { "database": "UniProtKB", "id": "Q9H0I3", "url": "https://www.uniprot.org/uniprotkb/Q9H0I3#function" }, { "database": "UniProtKB", "id": "Q22KK0", "url": "https://www.uniprot.org/uniprotkb/Q22KK0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5XJN6", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cfap263", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041010-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-163", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5XJN6", "url": "https://alphafold.ebi.ac.uk/entry/Q5XJN6", "database": "AlphaFoldDB", "categories": [] }, { "id": "450041", "url": "https://www.ncbi.nlm.nih.gov/gene/450041", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:450041", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:450041", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5XJN6", "url": "https://www.orthodb.org/?gene=Q5XJN6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15654", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15654", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15654:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15654:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13870", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13870", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5XJN6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5XJN6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001006061", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006061", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q5XJN6", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5XJN6-1", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041010-163", "url": "https://zfin.org/ZDB-GENE-041010-163", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAEMTEDSKSDTARKQLVELVDLNLTSNAALNAEIDLFDRYISRLDLRTFETVWKWQNLSTEKIPGRKAKVRTPGRQQLLTLEQKCVVAKSVYKKMIEDLKIAKIHSEKQLDNYKATLEEADIHLAEIKKERSHFKRNIVEELEDKKSMTMSAEKVMRYIEDKIKAKDILIEKLHRKNSALLTHKKKQQAQLRQQEEMAEGVTVLDFELLKFENIRFRKQLDEQNLKQVNLKLLAVKTLQTLNSNKEKLHILTNESEMLSSDTALRTKLLVKIEEETEQAEEERHKAEALNRKLRDQLADFHVPHVLQYIKLKESHGQLQKSVREWERKVEIAEMALKTYTKSWDKLRFAAGAGLVPI", "length": 358, "header": "sp|Q5XJN6-1|CF263_DANRE Isoform 1 of Cilia- and flagella-associated protein 263 OS=Danio rerio OX=7955 GN=cfap263 PE=2 SV=1 CANONICAL=Q5XJN6-1" }, "isoforms": [ { "isoform_ac": "Q5XJN6-1", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6/entry#Q5XJN6-1", "sequence": { "sequence": "MAEMTEDSKSDTARKQLVELVDLNLTSNAALNAEIDLFDRYISRLDLRTFETVWKWQNLSTEKIPGRKAKVRTPGRQQLLTLEQKCVVAKSVYKKMIEDLKIAKIHSEKQLDNYKATLEEADIHLAEIKKERSHFKRNIVEELEDKKSMTMSAEKVMRYIEDKIKAKDILIEKLHRKNSALLTHKKKQQAQLRQQEEMAEGVTVLDFELLKFENIRFRKQLDEQNLKQVNLKLLAVKTLQTLNSNKEKLHILTNESEMLSSDTALRTKLLVKIEEETEQAEEERHKAEALNRKLRDQLADFHVPHVLQYIKLKESHGQLQKSVREWERKVEIAEMALKTYTKSWDKLRFAAGAGLVPI", "length": 358, "header": "sp|Q5XJN6-1|CF263_DANRE Isoform 1 of Cilia- and flagella-associated protein 263 OS=Danio rerio OX=7955 GN=cfap263 PE=2 SV=1 CANONICAL=Q5XJN6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:450041", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:450041", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JWV4-1", "protein_name": "Cilia- and flagella-associated protein 263", "gene_name": "Cfap263", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEEDSDSAITDSQTEEEGELPVIQLCGLVEELSYGNSALKTETEMFEKYYSRLEPRDHRMPRLSDIKISAAEFSQLRSRRKSKIRGGMDRLVGLTVEQKLDLVQKELEDTRDEIRHMRANAERDLQHHEAIIEEADIRWNEVQRAVHDFEKDILKTVSKKKGSILATQKVMKYIEDMNRRRDNMKDKLCLKNVSLKVQRKKMLLQLRQKEEVGEALHDVDFQQLKIENAQFLETIEARNQELIQLKLSSGNTLHVLNTYKNKLHRAMEVYINLDKEILLRNEMLGKIEKETIQAEEDRAKAYVLNSKLRKQLAEFRAPQVMMYVREKILNGDLEKTIKMWERKVEIAEMSLKGYRKAWNKMKTSDEQLQMVRPPGK", "length": 377 }, "evidence": [ { "id": "RGD:1565763", "url": "https://alliancegenome.org/gene/RGD:1565763#orthology", "database": "AGR" }, { "id": "MGI:3606076", "url": "https://alliancegenome.org/gene/MGI:3606076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-163#orthology", "database": "AGR" }, { "id": "HGNC:25002", "url": "https://alliancegenome.org/gene/HGNC:25002#orthology", "database": "AGR" }, { "id": "FB:FBgn0031235", "url": "https://alliancegenome.org/gene/FB:FBgn0031235#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C5T8-1", "protein_name": "Cilia- and flagella-associated protein 263", "gene_name": "Cfap263", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEEDSDSVITDSQAEEEGELPVIQLCGLVEELSYGNSALKTETEMFEKYYSRLEPRDHRMTRLSDIKITAAEFSQLRSRRKSKARGGLDRTLGLTVEQKLELVQKELEDTRDEIRHMRANAERDLQHHEAIIEEADIRWNEVQKAVHEFEKDILKTISKKKGSILATQKVMKYIEDMNRRRDNIKDKLCLKNVSLKVQRKKMLSQLRQKEEVGEALHDVDFQQLKIENAQFLETIEARNKELIQLKLASGNTLQVLNTYKNKLHRAMEIYVNLDKEILLRNELLGKIEKETIQAEEDRAKAHILNDKLRKQLAEFRAPQVMMYVKEKILNGELEKTIKMWERKVEIAEMSLKGYRKAWNKMKTSDEQLQIIRPPGK", "length": 377 }, "evidence": [ { "id": "RGD:1565763", "url": "https://alliancegenome.org/gene/RGD:1565763#orthology", "database": "AGR" }, { "id": "MGI:3606076", "url": "https://alliancegenome.org/gene/MGI:3606076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-163#orthology", "database": "AGR" }, { "id": "HGNC:25002", "url": "https://alliancegenome.org/gene/HGNC:25002#orthology", "database": "AGR" }, { "id": "FB:FBgn0031235", "url": "https://alliancegenome.org/gene/FB:FBgn0031235#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0I3-1", "protein_name": "Cilia- and flagella-associated protein 263", "gene_name": "CFAP263", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDDESESVLSDSHEGSELELPVIQLCGLVEELSYVNSALKTETEMFEKYYAKLEPRDQRPPRLSEIKISAADYAQFRGRRRSKSRTGMDRGVGLTADQKLELVQKEVADMKDDLRHTRANAERDLQHHEAIIEEAEIRWSEVSREVHEFEKDILKAISKKKGSILATQKVMKYIEDMNRRRDNMKEKLRLKNVSLKVQRKKMLLQLRQKEEVSEALHDVDFQQLKIENAQFLETIEARNQELTQLKLSSGNTLQVLNAYKSKLHKAMEIYLNLDKEILLRKELLEKIEKETLQVEEDRAKAEAVNKRLRKQLAEFRAPQVMTYVREKILNADLEKSIRMWERKVEIAEMSLKGHRKAWNRMKITNEQLQADYLAGK", "length": 377 }, "evidence": [ { "id": "RGD:1565763", "url": "https://alliancegenome.org/gene/RGD:1565763#orthology", "database": "AGR" }, { "id": "MGI:3606076", "url": "https://alliancegenome.org/gene/MGI:3606076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-163#orthology", "database": "AGR" }, { "id": "HGNC:25002", "url": "https://alliancegenome.org/gene/HGNC:25002#orthology", "database": "AGR" }, { "id": "FB:FBgn0031235", "url": "https://alliancegenome.org/gene/FB:FBgn0031235#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VPL8-1", "protein_name": "Cilia- and flagella-associated protein 263", "gene_name": "Dmel\\CG13693", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMSTSGHSLKTDTQSRRSVKSHPSKLHVFEYAAPQDLDVVAIIYKFYLEDFRNFTEEERQLRLSSLDAIDMLHTIEQVHNDVATLRLENHIMVEFLEKNDPKLLLGLRQRRTSILRKLQTKRGSAQGSHGVNSRHSSSKRSIPMSVNQLVSISGISAPEKRRGMDYKLNFKAKAEMAEKRAAEVEKRVADIERNAMTEVKQLRAKIEELRFRSEETIETENNFMLHFLRDENDVAFLESATERQIERKLRKFTSNWFKNARALLGTMKLTIVSLQETCQQHRADLITKSDLSGILTAVDFEKLIIKRTELVNQLEEKNIHMAGLKGVTGKTSLAMTEEKQAMMNLETEMRTVLNRTDEVTRAIQKLEKEVAAVQMHNTKDYVTLDELRAQLQDYEAPSVSEYIERKEEAHVLEKEEKMLQRKIYILNMKLNNAIRRRNRLEEN", "length": 443 }, "evidence": [ { "id": "RGD:1565763", "url": "https://alliancegenome.org/gene/RGD:1565763#orthology", "database": "AGR" }, { "id": "MGI:3606076", "url": "https://alliancegenome.org/gene/MGI:3606076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-163#orthology", "database": "AGR" }, { "id": "HGNC:25002", "url": "https://alliancegenome.org/gene/HGNC:25002#orthology", "database": "AGR" }, { "id": "FB:FBgn0031235", "url": "https://alliancegenome.org/gene/FB:FBgn0031235#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "Q5XJN6", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "Q5XJN6", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6" } ], "pmid": "" }, { "name": "centriolar satellite", "id": "GO:0034451", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034451", "evidence": [ { "database": "UniProtKB", "id": "Q5XJN6", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "Q5XJN6", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "Q5XJN6", "url": "https://www.uniprot.org/uniprotkb/Q5XJN6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 24, "end_pos": 26 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 58, "end_pos": 60 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q5XJP1-1", "uniprot_ac": "Q5XJP1", "uniprot_id": "EIPR1_DANRE", "mass": { "chemical_mass": 43588.0, "monoisotopic_mass": 43588.0 }, "refseq": {}, "gene_names": [ { "name": "eipr1", "type": "recommended", "evidence": [ { "id": "Q5XJP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1" } ] }, { "name": "tssc1", "type": "synonym", "evidence": [ { "id": "Q5XJP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1" } ] }, { "name": "zgc:101720", "type": "synonym", "evidence": [ { "id": "Q5XJP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1" } ] } ], "protein_names": [ { "name": "EARP-interacting protein homolog", "type": "recommended", "evidence": [ { "id": "Q5XJP1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May act as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network.", "evidence": [ { "database": "UniProtKB", "id": "Q5XJP1", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1#function" }, { "database": "UniProtKB", "id": "Q53HC9", "url": "https://www.uniprot.org/uniprotkb/Q53HC9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q5XJP1", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "eipr1", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041010-167", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-167", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q5XJP1", "url": "https://alphafold.ebi.ac.uk/entry/Q5XJP1", "database": "AlphaFoldDB", "categories": [] }, { "id": "450045", "url": "https://www.ncbi.nlm.nih.gov/gene/450045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:450045", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:450045", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q5XJP1", "url": "https://www.orthodb.org/?gene=Q5XJP1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14205:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14205:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23609", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23609", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q5XJP1", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q5XJP1", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0AB13AAD1", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13AAD1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HMS9", "url": "https://www.uniprot.org/uniprotkb/A0AC58HMS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HMS9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HMS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5XJP1", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5XJP1-1", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041010-167", "url": "https://zfin.org/ZDB-GENE-041010-167", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEDDAPVIYGLEFQARALTAQTAETDAIRFLVGTQSLKFDNQIHIIDFDDENNMINKSVLLHDAGEIWHISGSPADKAVLTTCYNKTSESRVLTCAAVWRMPPEWESGNHESPDDSSNNPQTLELLCHLDNSAHGSMACVLWEPMGDGKRVISLAENHVLLWDLQESSAKATISSSATLEGKGQLKFTAGKWSPHHNCTQLATANDTAIRGWDLRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDVRHISEPVKCLEEHSHWVWSVRYNHSHDQLLLTASSDSRVILSNMVSISSEPFGHLVDDDDLSDPEENQQEDKGKEPLQDSIISTYEEHEDSVYAVEWSAADPWLFASLSYDGRLVINRVPRALKYRILL", "length": 387, "header": "sp|Q5XJP1-1|EIPR1_DANRE Isoform 1 of EARP-interacting protein homolog OS=Danio rerio OX=7955 GN=eipr1 PE=2 SV=1 CANONICAL=Q5XJP1-1" }, "isoforms": [ { "isoform_ac": "A0AB13AAD1-1", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1/entry#A0AB13AAD1-1", "sequence": { "sequence": "MEDDAPVIYGLEFQARALTAQTAETDAIRFLVGTQSLKFDNQIHIIDFDDENNMINKSVLLHDAGEIWHISGSPADKAVLTTCYNKTSESRVLTCAAVWRMPPEWESGSHESPDDSSNNPQTLELLCHLDNSAHGSMACVLWEPMGDGKRVISLAENHVLLWDLQESSAKATISSSATLEGKGQLKFTAGKWSPHHNCTQLATANDTAIRGWDLRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDVRHISEPVKCLEEHSHWVWSVRYNHSHDQLLLTASSDSRVILSNMVSISSEPFGHLVDDDDLSDPEENQQEAKGKEPLQDSIISTYEEHEDSVYAVEWSAADPWLFASLSYDGRLVINRVPRALKYRILL", "length": 387, "header": "tr|A0AB13AAD1-1|EIPR1_DANRE Computationally mapped isoform of EARP-interacting protein homolog OS=Danio rerio OX=7955 GN=eipr1 PE=2 SV=1 CANONICAL=Q5XJP1-1" }, "locus": {} }, { "isoform_ac": "A0AC58HMS9-1", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1/entry#A0AC58HMS9-1", "sequence": { "sequence": "MVNKMEDDAPVIYGLEFQARALTAQTAETDAIRFLVGTQSLKFDNQIHIIDFDDENNMINKSVLLHDAGEIWHISGSPADKAVLTTCYNKTSESRVLTCAAVWRMPPEWESGSHESPDDSSNNPQTLELLCHLDNSAHGSMACVLWEPMGDGKRVISLAENHVLLWDLQESSAKATISSSATLEGKGQLKFTAGKWSPHHNCTQLATANDTAIRGWDLRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDVRHISEPVKCLEEHSHWVWSVRYNHSHDQLLLTASSDSRVILSNMVSISSEPFGHLVDDDDLSDPEENQQEDKGKEPLQDSIISTYEEHEDSVYAVEWSAADPWLFASLSYDGRLVINRVPRALKYRILL", "length": 391, "header": "tr|A0AC58HMS9-1|A0AC58HMS9_DANRE Computationally mapped isoform of EARP-interacting protein homolog isoform X1 OS=Danio rerio OX=7955 GN=eipr1 PE=1 SV=1 CANONICAL=Q5XJP1-1" }, "locus": {} }, { "isoform_ac": "Q5XJP1-1", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1/entry#Q5XJP1-1", "sequence": { "sequence": "MEDDAPVIYGLEFQARALTAQTAETDAIRFLVGTQSLKFDNQIHIIDFDDENNMINKSVLLHDAGEIWHISGSPADKAVLTTCYNKTSESRVLTCAAVWRMPPEWESGNHESPDDSSNNPQTLELLCHLDNSAHGSMACVLWEPMGDGKRVISLAENHVLLWDLQESSAKATISSSATLEGKGQLKFTAGKWSPHHNCTQLATANDTAIRGWDLRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDVRHISEPVKCLEEHSHWVWSVRYNHSHDQLLLTASSDSRVILSNMVSISSEPFGHLVDDDDLSDPEENQQEDKGKEPLQDSIISTYEEHEDSVYAVEWSAADPWLFASLSYDGRLVINRVPRALKYRILL", "length": 387, "header": "sp|Q5XJP1-1|EIPR1_DANRE Isoform 1 of EARP-interacting protein homolog OS=Danio rerio OX=7955 GN=eipr1 PE=2 SV=1 CANONICAL=Q5XJP1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene expression profiling of zebrafish embryonic retinal pigment epithelium in vivo.", "journal": "Invest. Ophthalmol. Vis. Sci.", "date": "2007", "authors": "Leung Yuk Fai, Ma Ping, Dowling John E", "evidence": [ { "database": "UniProtKB", "id": "A0AB13AAD1", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAD1" } ], "reference": [ { "type": "PubMed", "id": "17251491", "url": "https://glygen.org/publication/PubMed/17251491" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0AB13AAD1", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAD1" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "A0AB13AAD1", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAD1" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] }, { "title": "Nxhl Controls Angiogenesis by Targeting VE-PTP Through Interaction With Nucleolin.", "journal": "Front. Cell Dev. Biol.", "date": "2021", "authors": "Luo Honglin, Zhang Yongde, Deng Yanfei, Li Lequn, Sheng Zhaoan, Yu Yanling, Lin Yong, Chen Xiaohan, Feng Pengfei", "evidence": [ { "database": "UniProtKB", "id": "A0AB13AAD1", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAD1" } ], "reference": [ { "type": "PubMed", "id": "34733844", "url": "https://glygen.org/publication/PubMed/34733844" } ] } ], "pathway": [ { "id": "dre:450045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:450045", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q53HC9-1", "protein_name": "EARP and GARP complex-interacting protein 1", "gene_name": "EIPR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQAGEIWHISASPADRGVLTTCYNRTSDSKVLTCAAVWRMPKELESGSHESPDDSSSTAQTLELLCHLDNTAHGNMACVVWEPMGDGKKIISLADNHILLWDLQESSSQAVLASSASLEGKGQLKFTSGRWSPHHNCTQVATANDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWNVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDISDQEDHRSEEKSKEPLQDNVIATYEEHEDSVYAVDWSSADPWLFASLSYDGRLVINRVPRALKYHILL", "length": 387 }, "evidence": [ { "id": "RGD:1305817", "url": "https://alliancegenome.org/gene/RGD:1305817#orthology", "database": "AGR" }, { "id": "MGI:1289332", "url": "https://alliancegenome.org/gene/MGI:1289332#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-167", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-167#orthology", "database": "AGR" }, { "id": "HGNC:12383", "url": "https://alliancegenome.org/gene/HGNC:12383#orthology", "database": "AGR" }, { "id": "FB:FBgn0036292", "url": "https://alliancegenome.org/gene/FB:FBgn0036292#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5PPK9-1", "protein_name": "EARP and GARP complex-interacting protein 1", "gene_name": "Eipr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQAGEIWHISASPADKGVLATCYNKTSDSRVQACAAVWRMPKELESGSHESPEDPASTAQTLELLCHLDNGAQGNVACVVWEPMGDGKKVISLADSHILLWDLQPSSSQAVLASSAALEGRGQLKFTSGRWSPHHNCTQVATASDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDDDVSDPEEHHTEKSKEPLQDNVIATYEEHEDSVYAVDWASADPWLFASLSYDGRLVINRVPRALKYHILL", "length": 386 }, "evidence": [ { "id": "RGD:1305817", "url": "https://alliancegenome.org/gene/RGD:1305817#orthology", "database": "AGR" }, { "id": "MGI:1289332", "url": "https://alliancegenome.org/gene/MGI:1289332#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-167", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-167#orthology", "database": "AGR" }, { "id": "HGNC:12383", "url": "https://alliancegenome.org/gene/HGNC:12383#orthology", "database": "AGR" }, { "id": "FB:FBgn0036292", "url": "https://alliancegenome.org/gene/FB:FBgn0036292#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K0G5-1", "protein_name": "EARP and GARP complex-interacting protein 1", "gene_name": "Eipr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDDAPVIYGLEFQARALTPQTAETDAIRFLVGTQSLKYDNQIHIIDFDDENNIINKNVLLHQAGEIWHISASPADKGVLATCYNKTTDSRVQACAAVWRMPKELESGSHESPDDPASTAQTLELLCHLDNSAQGNVACVVWEPMGDGKKVISLADSHILLWDLQPSSSQAVLASSATLEGRGQLKFTAGRWSPHHNCTQVATASDTTLRGWDTRSMSQIYCIENAHGQLVRDLDFNPNKQYYLASCGDDCKVKFWDTRNVTEPVKTLEEHSHWVWSVRYNHSHDQLVLTGSSDSRVILSNMVSISSEPFGHLVDDGDISDPEEHHAEKSKEPLQDNVIATYEEHEDSVYAVDWASADPWLFASLSYDGRLVINRVPRALKYHILL", "length": 386 }, "evidence": [ { "id": "RGD:1305817", "url": "https://alliancegenome.org/gene/RGD:1305817#orthology", "database": "AGR" }, { "id": "MGI:1289332", "url": "https://alliancegenome.org/gene/MGI:1289332#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-167", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-167#orthology", "database": "AGR" }, { "id": "HGNC:12383", "url": "https://alliancegenome.org/gene/HGNC:12383#orthology", "database": "AGR" }, { "id": "FB:FBgn0036292", "url": "https://alliancegenome.org/gene/FB:FBgn0036292#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VTY5-1", "protein_name": "EIPR1-like beta-propeller domain-containing protein", "gene_name": "anon-WO0172774.52", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDENSLIYGLELQARALTPQYGESNDVCFFIATNSLKPTNQVHLIQYEEEQGSVQSKVFEHALGEVWKLNSCPRNPRLLASVYNVQKGAQVLTKAALFTLPENLNPDPEQLKSEYLPWEQVEVLDTEALGERVKTIEFHPNQDTLACVVDNKVAVMQRAESSTRVVAEVPASGSSSGSAKHTQHFTSGKWSHHHQGHQFLTLQDGNLSAYDVRDTQHCAWSINDAHGQMVRDLDCNPNKQCHLVTGGDDGYLRIWDCRMPKAPVFERSDHSHWVWCVRFNTFHDQLILSSSSDCKVLLTCAGSVSSETQVQAGLDESNFSGADAEERHKLLPDGLLQTFDQHEDSVYCAEWSNVDPWIFASLSYDGRVIISKVPKQYKYQIIF", "length": 383 }, "evidence": [ { "id": "RGD:1305817", "url": "https://alliancegenome.org/gene/RGD:1305817#orthology", "database": "AGR" }, { "id": "MGI:1289332", "url": "https://alliancegenome.org/gene/MGI:1289332#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-167", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-167#orthology", "database": "AGR" }, { "id": "HGNC:12383", "url": "https://alliancegenome.org/gene/HGNC:12383#orthology", "database": "AGR" }, { "id": "FB:FBgn0036292", "url": "https://alliancegenome.org/gene/FB:FBgn0036292#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "Q5XJP1", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "Q5XJP1", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1" } ], "pmid": "" }, { "name": "endocytic recycling", "id": "GO:0032456", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032456", "evidence": [ { "database": "UniProtKB", "id": "Q5XJP1", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1" } ], "pmid": "" }, { "name": "regulation of transport", "id": "GO:0051049", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051049", "evidence": [ { "database": "UniProtKB", "id": "Q5XJP1", "url": "https://www.uniprot.org/uniprotkb/Q5XJP1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 281, "end_pos": 283 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q641M3-1", "uniprot_ac": "Q641M3", "uniprot_id": "TMM18_DANRE", "mass": { "chemical_mass": 17817.0, "monoisotopic_mass": 17817.0 }, "refseq": { "ac": "NP_001005601", "name": "transmembrane protein 18", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005601" }, "gene_names": [ { "name": "tmem18", "type": "recommended", "evidence": [ { "id": "Q641M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q641M3" } ] }, { "name": "tmem18", "type": "synonym", "evidence": [ { "id": "NP_001005601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005601" } ] }, { "name": "zgc:101011", "type": "synonym", "evidence": [ { "id": "NP_001005601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005601" }, { "id": "Q641M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q641M3" } ] } ], "protein_names": [ { "name": "Transmembrane protein 18", "type": "recommended", "evidence": [ { "id": "Q641M3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q641M3/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 18", "type": "synonym", "evidence": [ { "id": "NP_001005601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005601" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC082297.1, EH453540.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505393, SAMEA4476758 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC082297.1. On Jul 6, 2005 this sequence version replaced XP_701594.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001005601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005601" } ] } ], "disease": [ { "disease_id": "DOID:14221", "recommended_name": { "id": "DOID:14221", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14221", "name": "abdominal obesity-metabolic syndrome 1", "description": "An abdominal obesity-metabolic syndrome characterized by insulin resistance and hyperinsulinemia, dyslipidemia, essential hypertension, abdominal obesity, glucose intolerance or noninsulin-dependent diabetes mellitus and an increased risk of cardiovascular events." }, "synonyms": [ { "id": "DOID:14221", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14221", "name": "dysmetabolic syndrome X", "description": "" }, { "id": "DOID:14221", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14221", "name": "metabolic syndrome X", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "metabolic syndrome X", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "abdominal obesity-metabolic syndrome 1", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "metabolic syndrome type X", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "AOMS1", "description": "" }, { "id": "MONDO:0011565", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011565", "name": "abdominal obesity metabolic syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "14221", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14221" } ] }, { "disease_id": "DOID:9352", "recommended_name": { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin." }, "synonyms": [ { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "NIDDM", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type II diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "insulin resistance", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity." }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "NIDDM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2D", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM - type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin-dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus non-insulin dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, type 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "NIDDM1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, type 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "type 2 diabetes mellitus 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "NIDDM3", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, type 4", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] }, { "disease_id": "DOID:9970", "recommended_name": { "id": "DOID:9970", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness." }, "synonyms": [ { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "inherited obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity (disease)", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "leanness, inherited, autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "monogenic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, association with, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, early-onset, susceptibility to, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, late-onset, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, mild, early-onset, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, severe, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, severe, and type II diabetes, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, susceptibility to, Autosomal recessive", "description": "" }, { "id": "MIM:601665", "resource": "MIM", "url": "https://www.omim.org/entry/601665", "name": "Obesity", "description": "Obesity" } ], "unlinked_id_list": [], "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q641M3", "url": "https://www.uniprot.org/uniprotkb/Q641M3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmem18", "url": "https://www.uniprot.org/uniprotkb/Q641M3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040927-26", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040927-26", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q641M3", "url": "https://alphafold.ebi.ac.uk/entry/Q641M3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000036704", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000036704", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "449559", "url": "https://www.ncbi.nlm.nih.gov/gene/449559", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:449559", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449559", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TFSKQQY", "url": "https://omabrowser.org/oma/group/TFSKQQY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q641M3", "url": "https://www.orthodb.org/?gene=Q641M3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22593", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22593", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22593:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22593:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14770", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14770", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q641M3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q641M3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001005601", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005601", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "Q641M3", "url": "https://www.uniprot.org/uniprotkb/Q641M3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q641M3-1", "url": "https://www.uniprot.org/uniprotkb/Q641M3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040927-26", "url": "https://zfin.org/ZDB-GENE-040927-26", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTASNTKNASAIPIDKFSNVRITSIWTFLQSVDWSEPWLMALLAFHVFCFAFTLLSCKYYRIQICHFLLMVAMVYSAEYLNELAAMNWRSFSKFQYFDSKGMFISLVYSVPLLLNTVIIVAVWVWRTFSTMTELKILQLKRKAARENHKKTQ", "length": 152, "header": "sp|Q641M3-1|TMM18_DANRE Isoform 1 of Transmembrane protein 18 OS=Danio rerio OX=7955 GN=tmem18 PE=2 SV=1 CANONICAL=Q641M3-1" }, "isoforms": [ { "isoform_ac": "Q641M3-1", "url": "https://www.uniprot.org/uniprotkb/Q641M3/entry#Q641M3-1", "sequence": { "sequence": "MTASNTKNASAIPIDKFSNVRITSIWTFLQSVDWSEPWLMALLAFHVFCFAFTLLSCKYYRIQICHFLLMVAMVYSAEYLNELAAMNWRSFSKFQYFDSKGMFISLVYSVPLLLNTVIIVAVWVWRTFSTMTELKILQLKRKAARENHKKTQ", "length": 152, "header": "sp|Q641M3-1|TMM18_DANRE Isoform 1 of Transmembrane protein 18 OS=Danio rerio OX=7955 GN=tmem18 PE=2 SV=1 CANONICAL=Q641M3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:449559", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449559", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1Z903-1", "protein_name": "Transmembrane protein 18", "gene_name": "Tmem18", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHPGQIEVNEINGYWTFLLSIDWKDPWLIGLILAHILTTTTALLSRNSSNFQVFLFLVLLLAVYFTESINEFAANNWSSFSRQQYFDSNGLFISTVFSIPILLNCMLLIGTWLYNSTQLMVTLKTAQLKERARKERQTKADSESIAHKKAE", "length": 151 }, "evidence": [ { "id": "RGD:1359389", "url": "https://alliancegenome.org/gene/RGD:1359389#orthology", "database": "AGR" }, { "id": "MGI:2387176", "url": "https://alliancegenome.org/gene/MGI:2387176#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040927-26", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040927-26#orthology", "database": "AGR" }, { "id": "HGNC:25257", "url": "https://alliancegenome.org/gene/HGNC:25257#orthology", "database": "AGR" }, { "id": "FB:FBgn0050051", "url": "https://alliancegenome.org/gene/FB:FBgn0050051#orthology", "database": "AGR" }, { "id": "Q641M3", "url": "https://omabrowser.org/oma/group/Q641M3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "G3HBH6-1", "protein_name": "Transmembrane protein 18", "gene_name": "Tmem18", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSPFSVKAFPVSIPAVIMETDWTEPWLLGLVVFHLLCLLLTCFSSQRYKLQIGHFLCLVLLVYFAEYINEVAAMNWRSFSKYQYFDSRGMFISIVFSAPLLFNAMIIVIMWVQKTLNVMSDLKRMQEKRKRRRKEE", "length": 137 }, "evidence": [ { "id": "Q641M3", "url": "https://omabrowser.org/oma/group/Q641M3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q3SZ36-1", "protein_name": "Transmembrane protein 18", "gene_name": "TMEM18", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPSAFSVSRFPVSIPAVITQTDWTEPWLVGLAGFHVLCLLLTCFSSQRYRLQVGHFLCLVTLVYCAEYINEVAAMNWRLFSKHQYFDSRGMFISLVFSAPLLLNALVIVVLWVRKTLVVMTDLRSLREQRRARARPKEE", "length": 139 }, "evidence": [ { "id": "Q641M3", "url": "https://omabrowser.org/oma/group/Q641M3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3TUD9-1", "protein_name": "Transmembrane protein 18", "gene_name": "Tmem18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSAYSVRSFPVSIPAVIMETDWTEPWLLGLLAFHLLCLLLTCFSSQRYKLQIGHFLCLVVLVYSAEYINEVAAVNWRLFSKYQYFDSRGMFISLVFSAPLLFNAMLIVIMWVRKTLTVMTDLKTLQEERKERRRRRKEE", "length": 140 }, "evidence": [ { "id": "RGD:1359389", "url": "https://alliancegenome.org/gene/RGD:1359389#orthology", "database": "AGR" }, { "id": "MGI:2387176", "url": "https://alliancegenome.org/gene/MGI:2387176#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040927-26", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040927-26#orthology", "database": "AGR" }, { "id": "HGNC:25257", "url": "https://alliancegenome.org/gene/HGNC:25257#orthology", "database": "AGR" }, { "id": "FB:FBgn0050051", "url": "https://alliancegenome.org/gene/FB:FBgn0050051#orthology", "database": "AGR" }, { "id": "Q641M3", "url": "https://omabrowser.org/oma/group/Q641M3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5F410-1", "protein_name": "Transmembrane protein 18", "gene_name": "TMEM18", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRSVAVAMEQPLHGPPGLSTILARTDWAEPWLLGLAGFHVLCFLLTCFSFQHYRVQIGHFLCMVCLVYCAEYINELAAMNWRLFSKYQYFDSRGMFISLVFSAPLLVNTIIIVVNWVYRTLNVMTELKTLQQRIKAEKDKKK", "length": 142 }, "evidence": [ { "id": "Q641M3", "url": "https://omabrowser.org/oma/group/Q641M3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6DGF8-1", "protein_name": "Transmembrane protein 18", "gene_name": "Tmem18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPYSVRVFPVSIPAVIMETDWTEPWLLGLLAFHLLCLLLTCFSAQRYKLQIGHFLCLVVLVYCAEYINEVAAMNWRLFAKYQYFDSRGMFISLVFSAPLLFNAMVIVIMWVRKTLTVMSDLKNLQERRKERKRRRKEE", "length": 140 }, "evidence": [ { "id": "RGD:1359389", "url": "https://alliancegenome.org/gene/RGD:1359389#orthology", "database": "AGR" }, { "id": "MGI:2387176", "url": "https://alliancegenome.org/gene/MGI:2387176#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040927-26", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040927-26#orthology", "database": "AGR" }, { "id": "HGNC:25257", "url": "https://alliancegenome.org/gene/HGNC:25257#orthology", "database": "AGR" }, { "id": "FB:FBgn0050051", "url": "https://alliancegenome.org/gene/FB:FBgn0050051#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96B42-1", "protein_name": "Transmembrane protein 18", "gene_name": "TMEM18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSAFSVSSFPVSIPAVLTQTDWTEPWLMGLATFHALCVLLTCLSSRSYRLQIGHFLCLVILVYCAEYINEAAAMNWRLFSKYQYFDSRGMFISIVFSAPLLVNAMIIVVMWVWKTLNVMTDLKNAQERRKEKKRRRKED", "length": 140 }, "evidence": [ { "id": "RGD:1359389", "url": "https://alliancegenome.org/gene/RGD:1359389#orthology", "database": "AGR" }, { "id": "MGI:2387176", "url": "https://alliancegenome.org/gene/MGI:2387176#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040927-26", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040927-26#orthology", "database": "AGR" }, { "id": "HGNC:25257", "url": "https://alliancegenome.org/gene/HGNC:25257#orthology", "database": "AGR" }, { "id": "FB:FBgn0050051", "url": "https://alliancegenome.org/gene/FB:FBgn0050051#orthology", "database": "AGR" }, { "id": "Q641M3", "url": "https://omabrowser.org/oma/group/Q641M3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "Q641M3", "url": "https://www.uniprot.org/uniprotkb/Q641M3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "Q641M3", "url": "https://www.uniprot.org/uniprotkb/Q641M3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fat cell differentiation", "id": "GO:0045444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045444", "evidence": [ { "database": "UniProtKB", "id": "Q641M3", "url": "https://www.uniprot.org/uniprotkb/Q641M3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q66HX0-1", "uniprot_ac": "Q66HX0", "uniprot_id": "S35B1_DANRE", "mass": { "chemical_mass": 36812.0, "monoisotopic_mass": 36812.0 }, "refseq": { "ac": "NP_001004583", "name": "solute carrier family 35 member B1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004583" }, "gene_names": [ { "name": "slc35b1", "type": "recommended", "evidence": [ { "id": "Q66HX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HX0" } ] }, { "name": "slc35b1", "type": "synonym", "evidence": [ { "id": "NP_001004583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004583" } ] }, { "name": "wu:fj99g11", "type": "synonym", "evidence": [ { "id": "NP_001004583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004583" } ] }, { "name": "zgc:92284", "type": "synonym", "evidence": [ { "id": "NP_001004583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004583" }, { "id": "Q66HX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HX0" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member B1", "type": "recommended", "evidence": [ { "id": "Q66HX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HX0/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 35 member B1", "type": "synonym", "evidence": [ { "id": "NP_001004583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004583" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC081637.1, EG577056.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505374, SAMEA4476730 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC081637.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001004583", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004583" } ] }, { "annotation": "ATP:ADP antiporter that catalyzes the exchange of ATP and ADP across the endoplasmic reticulum (ER) membrane.", "evidence": [ { "database": "UniProtKB", "id": "Q66HX0", "url": "https://www.uniprot.org/uniprotkb/Q66HX0#function" }, { "database": "UniProtKB", "id": "P78383", "url": "https://www.uniprot.org/uniprotkb/P78383#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66HX0", "url": "https://www.uniprot.org/uniprotkb/Q66HX0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "slc35b1", "url": "https://www.uniprot.org/uniprotkb/Q66HX0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040912-148", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-148", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q66HX0", "url": "https://alphafold.ebi.ac.uk/entry/Q66HX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000038213", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000038213", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "447844", "url": "https://www.ncbi.nlm.nih.gov/gene/447844", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013657", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013657", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:447844", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:447844", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGAIGQV", "url": "https://omabrowser.org/oma/group/CGAIGQV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "Q66HX0", "url": "https://www.orthodb.org/?gene=Q66HX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10778", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10778", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10778:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10778:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08449", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08449", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q66HX0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q66HX0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001004583", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004583", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "34999", "url": "https://www.rhea-db.org/rhea/34999", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q66HX0", "url": "https://www.uniprot.org/uniprotkb/Q66HX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q66HX0-1", "url": "https://www.uniprot.org/uniprotkb/Q66HX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040912-148", "url": "https://zfin.org/ZDB-GENE-040912-148", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAAGKAASKPSLWQNERVRFAVCFCGVFVCYFYYGILQETITRADYTHAGKKEKFRYATTLVFIQCIINAAFARLLIQFFEGSKQDHTRSWLYGLCSLSYLGAMVSSNSALQYVNYPTQVLGKSCKPIPVMILGVTILRKKYPMAKYLCVFLIVGGVALFLYKPNKGSSTSDEHVFGFGEMLLLLSLTLDGLTGVVQDHMRGRFQTGANHMMLNVNMWSTLVLGIAVLWSGEVWEFLAFTDRYPSIIYNILLFGITSALGQTFIFMTVVYFGPLTCSIVTTTRKFFTILGSVLLFGNVISHMQWFGTILVFLGLGLDAKFGKSPKKTTH", "length": 329, "header": "sp|Q66HX0-1|S35B1_DANRE Isoform 1 of Solute carrier family 35 member B1 OS=Danio rerio OX=7955 GN=slc35b1 PE=2 SV=1 CANONICAL=Q66HX0-1" }, "isoforms": [ { "isoform_ac": "Q66HX0-1", "url": "https://www.uniprot.org/uniprotkb/Q66HX0/entry#Q66HX0-1", "sequence": { "sequence": "MAAGKAASKPSLWQNERVRFAVCFCGVFVCYFYYGILQETITRADYTHAGKKEKFRYATTLVFIQCIINAAFARLLIQFFEGSKQDHTRSWLYGLCSLSYLGAMVSSNSALQYVNYPTQVLGKSCKPIPVMILGVTILRKKYPMAKYLCVFLIVGGVALFLYKPNKGSSTSDEHVFGFGEMLLLLSLTLDGLTGVVQDHMRGRFQTGANHMMLNVNMWSTLVLGIAVLWSGEVWEFLAFTDRYPSIIYNILLFGITSALGQTFIFMTVVYFGPLTCSIVTTTRKFFTILGSVLLFGNVISHMQWFGTILVFLGLGLDAKFGKSPKKTTH", "length": 329, "header": "sp|Q66HX0-1|S35B1_DANRE Isoform 1 of Solute carrier family 35 member B1 OS=Danio rerio OX=7955 GN=slc35b1 PE=2 SV=1 CANONICAL=Q66HX0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:447844", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:447844", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F7FLA1-1", "protein_name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "gene_name": "Slc35b2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDASRWWAVVVLATLPSLGAGGESPEAPPQSWTQLWLFRFLLNVAGYASFMVPGYLLVQYLRRKNYLETGRGLCFPLVKACVFGNEPKAPDEVPLAPRTETAESTPSWQVLKLVFCAAGLQVSYLTWGVLQERVMTGSYGATATSPGEHFTDSQFLVLMNRVLALVVAGLYCILRKQPRHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMMMGKLVSRRSYEHWEYLTAGLISIGVSMFLLSSGPEPRSSPATTLSGLVLLAGYIAFDSFTSNWQDALFAYKMSSVQMMFGVNLFSCLFTVGSLLEQGALLEGARFMGRHSEFALHALLLSVCSAFGQLFIFYTIGQFGAAVFTIIMTLRQAIAILLSCLLYGHTVTVVGGLGVAVVFTALLLRVYARGRKQRGKKAVPTEPAVQKV", "length": 432 }, "evidence": [ { "id": "SGD:S000006165", "url": "https://alliancegenome.org/gene/SGD:S000006165#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P78383-1", "protein_name": "Solute carrier family 35 member B1", "gene_name": "SLC35B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSSSLVPDRLRLPLCFLGVFVCYFYYGILQEKITRGKYGEGAKQETFTFALTLVFIQCVINAVFAKILIQFFDTARVDRTRSWLYAACSISYLGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKPKKVVGIEEHTVGYGELLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTLLLGMGILFTGELWEFLSFAERYPAIIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISPMQWVGTVLVFLGLGLDAKFGKGAKKTSH", "length": 322 }, "evidence": [ { "id": "MGI:1343133", "url": "https://alliancegenome.org/gene/MGI:1343133#orthology", "database": "AGR" }, { "id": "HGNC:20798", "url": "https://alliancegenome.org/gene/HGNC:20798#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-148", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-148#orthology", "database": "AGR" }, { "id": "RGD:727783", "url": "https://alliancegenome.org/gene/RGD:727783#orthology", "database": "AGR" }, { "id": "FB:FBgn0250820", "url": "https://alliancegenome.org/gene/FB:FBgn0250820#orthology", "database": "AGR" }, { "id": "SGD:S000006165", "url": "https://alliancegenome.org/gene/SGD:S000006165#orthology", "database": "AGR" }, { "id": "Q66HX0", "url": "https://omabrowser.org/oma/group/Q66HX0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97858-1", "protein_name": "Solute carrier family 35 member B1", "gene_name": "Slc35b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASRSLVPDRLRLPLCFLGVFVCYFYYGILQEKITRGKYGEGPKQETFTFALTLVFIQCVINAMFAKILIQFFDTARVDRTRTWLYAACSVSYVGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKPKKVVGIEEHTVGFGELLLLMSLTLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTFLLGAGILFTGELWEFLSFAERYPTIIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISSMQWVGTVLVFLGLGLDAKFGKGTKKTSH", "length": 322 }, "evidence": [ { "id": "MGI:1343133", "url": "https://alliancegenome.org/gene/MGI:1343133#orthology", "database": "AGR" }, { "id": "HGNC:20798", "url": "https://alliancegenome.org/gene/HGNC:20798#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-148", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-148#orthology", "database": "AGR" }, { "id": "RGD:727783", "url": "https://alliancegenome.org/gene/RGD:727783#orthology", "database": "AGR" }, { "id": "FB:FBgn0250820", "url": "https://alliancegenome.org/gene/FB:FBgn0250820#orthology", "database": "AGR" }, { "id": "SGD:S000006165", "url": "https://alliancegenome.org/gene/SGD:S000006165#orthology", "database": "AGR" }, { "id": "Q66HX0", "url": "https://omabrowser.org/oma/group/Q66HX0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q12520-1", "protein_name": "UDP-galactose transporter homolog 1", "gene_name": "HUT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAGSTSSLVICAIGIYATFLTWALVQEPLATRTWPNSMGKFQFPNVISLIQASVAMMMGYLYLNWKKVEYPPRKMIKDHWKQLMLISFTQSSSGPLATTSLKHVDYLTYMLAKSCKMIPVLLVHLLLYRTPIASQKKVVALLVSLGVTIFTIGGNDGKKLKRSFNESGNDNKLQGFGLLFSSLFLDGLTNATQDKLLKANKAKEKGKQTLITGAHLMFTLNLFVILWNILYFIVIDCKQWDNAVSVLTMDPQVWGYLMLYSFCGAMGQCFIFYTLEQFGSLVLIMITVTRKMVSMILSIIVFGKSVRFQQWVGMFIVFGGITWEALNKKKANIPKAKSA", "length": 339 }, "evidence": [ { "id": "MGI:1343133", "url": "https://alliancegenome.org/gene/MGI:1343133#orthology", "database": "AGR" }, { "id": "HGNC:20798", "url": "https://alliancegenome.org/gene/HGNC:20798#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-148", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-148#orthology", "database": "AGR" }, { "id": "RGD:727783", "url": "https://alliancegenome.org/gene/RGD:727783#orthology", "database": "AGR" }, { "id": "FB:FBgn0250820", "url": "https://alliancegenome.org/gene/FB:FBgn0250820#orthology", "database": "AGR" }, { "id": "SGD:S000006165", "url": "https://alliancegenome.org/gene/SGD:S000006165#orthology", "database": "AGR" }, { "id": "Q66HX0", "url": "https://omabrowser.org/oma/group/Q66HX0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6V7K3-1", "protein_name": "Solute carrier family 35 member B1", "gene_name": "Slc35b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASRSLVPDRLRLPLCFLGVFVCYFYYGILQEKITRGKYGEGPKQETFTFALTLVFIQCVINAMFAKILIQFFDTARVDRTRTWLYAACSVSYVGAMVSSNSALQFVNYPTQVLGKSCKPIPVMLLGVTLLKKKYPLAKYLCVLLIVAGVALFMYKPKKVVGIEEHTVGFGELLLLLSLTLDGLTGVSQDHMRAHYQTGSNHMMLNINLWSTVLLGAGILFTGELWEFLSFAERYPTIIYNILLFGLTSALGQSFIFMTVVYFGPLTCSIITTTRKFFTILASVILFANPISSMQWVGTVLVFLGLGLDAKFGKGTKKTSH", "length": 322 }, "evidence": [ { "id": "MGI:1343133", "url": "https://alliancegenome.org/gene/MGI:1343133#orthology", "database": "AGR" }, { "id": "HGNC:20798", "url": "https://alliancegenome.org/gene/HGNC:20798#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-148", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-148#orthology", "database": "AGR" }, { "id": "RGD:727783", "url": "https://alliancegenome.org/gene/RGD:727783#orthology", "database": "AGR" }, { "id": "FB:FBgn0250820", "url": "https://alliancegenome.org/gene/FB:FBgn0250820#orthology", "database": "AGR" }, { "id": "SGD:S000006165", "url": "https://alliancegenome.org/gene/SGD:S000006165#orthology", "database": "AGR" }, { "id": "Q66HX0", "url": "https://omabrowser.org/oma/group/Q66HX0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TB61-1", "protein_name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "gene_name": "SLC35B2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"MDARWWAVVVLATLPSLGAGGESPEAPPQSWTQLWLFRFLLNVAGYASFMVPGYLLVQYLRRKNYLETGRGLCFPLVKACVFGNEPKAPDEVLLAPRTETAESTPSWQVLKLVFCASGLQVSYLTWGILQERVMTGSYGATATSPGEHFTDSQFLVLMNRVLALVVAGLYCVLRKQPRHGAPMYRYSFASLSNVLSSWCQYEALKFVSFPTQVLAKASKVIPVMMMGKLVSRRSYEHWEYLTAGLISIGVSMFLLSSGPEPRSSPATTLSGLVLLAGYIAFDSFTSNWQDALFAYKMSSVQMMFGVNLFSCLFTVGSLLEQGALLEGARFMGRHSEFALHALLLSICSAFGQLFIFYTIGQFGAAVFTIIMTLRQAIAILLSCLLYGHTVTVVGGLGVAVVFTALLLRVYARGRKQRGKKAVPTEPPVQKV", "length": 431 }, "evidence": [ { "id": "SGD:S000006165", "url": "https://alliancegenome.org/gene/SGD:S000006165#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9M9S6-1", "protein_name": "UDP-galactose/UDP-glucose transporter 3", "gene_name": "UTR3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MESHGSGLRRVLLLSFCVAGIWAAYIYQGILQETLSTKKFGEDGKRFEHLAFLNLAQNVICLVWSYIMIKLWSNGGSGGAPWWTYWSAGITNTIGPAMGIEALKYISYPAQVLAKSSKMIPVMLMGSLVYGIRYTLPEYLCTFLVAGGVSMFALLKTSSKTISKLAHPNAPLGYGLCFLNLAFDGFTNATQDSITARYPKTNAWDIMLGMNLWGTIYNMVYMFGLPHGSGFEAVQFCKQHPEAAWDILMYCLCGAVGQNFIFLTISRFGSLANTTITTTRKFVSIVVSSVLSGNPLSSKQWGCVSMVFGGLSYQIYLKWRKLQRMQKKKKA", "length": 331 }, "evidence": [ { "id": "Q66HX0", "url": "https://omabrowser.org/oma/group/Q66HX0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VDD7-1", "protein_name": "Solute carrier family 35 member B1 homolog", "gene_name": "meigo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNLPERSRFVIYAVGIFVCYFLYGIVQEKLTRGRYGEEVQTDGSVGERFTYALALVWVQCLCNYVFAKVLLTIRPQKEDTTNAGSYVACSLTYLLAMVSTNMAMRWVPYPTAVVGKSAKPIPVMILGVLIGRKSYSWTRYACVLTIVLGVILFMYKEGKVSNLPAETTLLGEVLLFLSLSMDGLTGAVQERIRAASAPSGQQMMRAMNFWSTLMLGVAMVFTGEAKEFMYFTIRHPEAWTHLSLIAVCGVLGQFFIFLMVASFGPLACSVVTTTRKFFTVLCSVLLFGNVLIARQWLGAVLVFAALFVDMLYGKKAPLATAKKPPVEGKLSEEKKLNS", "length": 338 }, "evidence": [ { "id": "MGI:1343133", "url": "https://alliancegenome.org/gene/MGI:1343133#orthology", "database": "AGR" }, { "id": "HGNC:20798", "url": "https://alliancegenome.org/gene/HGNC:20798#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-148", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-148#orthology", "database": "AGR" }, { "id": "RGD:727783", "url": "https://alliancegenome.org/gene/RGD:727783#orthology", "database": "AGR" }, { "id": "FB:FBgn0250820", "url": "https://alliancegenome.org/gene/FB:FBgn0250820#orthology", "database": "AGR" }, { "id": "SGD:S000006165", "url": "https://alliancegenome.org/gene/SGD:S000006165#orthology", "database": "AGR" }, { "id": "Q66HX0", "url": "https://omabrowser.org/oma/group/Q66HX0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VEI3-1", "protein_name": "Adenosine 3'-phospho 5'-phosphosulfate transporter 1", "gene_name": "sll", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYAYNKMGRVPELVICSFIVVTLLVIHFFSDLLRASLGGYYNQDVTLSQLVESQNSDYAWFLKLLVNCFGYSCVFVPGFLIYKYVGRINYLERGNKTFLHKAINMCITGNSGYDQLDAGTSTADKDRPAASTAPKRTSSQEAVQLLWCFGGLMISYLTWGVLQEKIMTQNYLNFTGESAKFKDSQFLVFSNRLLAFLVALAYLQWQPSPVRHRAPLYKYSYASFSNIMSAWFQYEALKFVNFPTQVLAKSCKIIPVMLMGKIMSKAKYESYEYVTALLISLGMIFFMSGSSDSSKASGVTTLTGIFLLSMYMVFDSFTANWQGSLFKSYGMTPLQMMCGVNLFSSIFTGASLSMQGGFMDSLAFATEHPKFVFDMVVLSVCSAVGQLFIYHTIDVFGPVVFTIIMTLRQAVAIMLSCFIYQHSISLLGIFGVLIVFVAIFLRVYCTQRLRAIRKRAEANKPKMAV", "length": 465 }, "evidence": [ { "id": "SGD:S000006165", "url": "https://alliancegenome.org/gene/SGD:S000006165#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "Q66HX0", "url": "https://www.uniprot.org/uniprotkb/Q66HX0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "Q66HX0", "url": "https://www.uniprot.org/uniprotkb/Q66HX0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "UDP-galactose transmembrane transporter activity", "id": "GO:0005459", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005459", "evidence": [ { "database": "UniProtKB", "id": "Q66HX0", "url": "https://www.uniprot.org/uniprotkb/Q66HX0" } ], "pmid": "" }, { "name": "UDP-glucose transmembrane transporter activity", "id": "GO:0005460", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005460", "evidence": [ { "database": "UniProtKB", "id": "Q66HX0", "url": "https://www.uniprot.org/uniprotkb/Q66HX0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "UDP-galactose transmembrane transport", "id": "GO:0072334", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072334", "evidence": [ { "database": "UniProtKB", "id": "Q66HX0", "url": "https://www.uniprot.org/uniprotkb/Q66HX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "34999", "name": "", "equation": "ADP(in) + ATP(out) = ADP(out) + ATP(in)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "34999", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34999" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "Q66HX8-1", "uniprot_ac": "Q66HX8", "uniprot_id": "GDAP2_DANRE", "mass": { "chemical_mass": 57515.0, "monoisotopic_mass": 57515.0 }, "refseq": { "ac": "NP_001004563", "name": "ganglioside-induced differentiation-associated protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004563" }, "gene_names": [ { "name": "gdap2", "type": "recommended", "evidence": [ { "id": "Q66HX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HX8" } ] }, { "name": "fc38e07", "type": "synonym", "evidence": [ { "id": "NP_001004563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004563" }, { "id": "Q66HX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HX8" } ] }, { "name": "gdap2", "type": "synonym", "evidence": [ { "id": "NP_001004563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004563" } ] }, { "name": "wu:fc38e07", "type": "synonym", "evidence": [ { "id": "NP_001004563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004563" }, { "id": "Q66HX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HX8" } ] }, { "name": "zgc:92235", "type": "synonym", "evidence": [ { "id": "NP_001004563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004563" }, { "id": "Q66HX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HX8" } ] } ], "protein_names": [ { "name": "Ganglioside-induced differentiation-associated protein 2", "type": "recommended", "evidence": [ { "id": "Q66HX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HX8/entry#names_and_taxonomy" } ] }, { "name": "ganglioside-induced differentiation-associated protein 2", "type": "synonym", "evidence": [ { "id": "NP_001004563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004563" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC081629.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC081629.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001004563", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004563" } ] } ], "disease": [ { "disease_id": "DOID:0111616", "recommended_name": { "id": "DOID:0111616", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111616", "name": "autosomal recessive spinocerebellar ataxia 27", "description": "An autosomal recessive cerebellar ataxia characterized by adult onset of progressive gait difficulties and other cerebellar signs that has_material_basis_in homozygous or compound heterozygous mutation in the GDAP2 gene on chromosome 1p12." }, "synonyms": [ { "id": "DOID:0111616", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111616", "name": "SCAR27", "description": "" }, { "id": "MONDO:0032706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032706", "name": "spinocerebellar ataxia, autosomal recessive 27", "description": "" }, { "id": "MONDO:0032706", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032706", "name": "SCAR27", "description": "" }, { "id": "MIM:618369", "resource": "MIM", "url": "https://www.omim.org/entry/618369", "name": "Spinocerebellar ataxia, autosomal recessive, 27", "description": "Spinocerebellar ataxia, autosomal recessive, 27" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111616", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111616" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66HX8", "url": "https://www.uniprot.org/uniprotkb/Q66HX8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gdap2", "url": "https://www.uniprot.org/uniprotkb/Q66HX8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040912-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-31", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "Q66HX8", "url": "https://alphafold.ebi.ac.uk/entry/Q66HX8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02905", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02905", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "447824", "url": "https://www.ncbi.nlm.nih.gov/gene/447824", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:447824", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:447824", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "Q66HX8", "url": "https://www.orthodb.org/?gene=Q66HX8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11106:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11106:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13716", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13716", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:Q66HX8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:Q66HX8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001004563", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58GDX4", "url": "https://www.uniprot.org/uniprotkb/A0AC58GDX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GDX4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GDX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q66HX8", "url": "https://www.uniprot.org/uniprotkb/Q66HX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q66HX8-1", "url": "https://www.uniprot.org/uniprotkb/Q66HX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040912-31", "url": "https://zfin.org/ZDB-GENE-040912-31", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDPLGARSQFVEVLNLPTWDQPQGVQDELDGENHYEEEEEEEEDNLTNQLNSVNSPFTFRQDINNKIVLFNGDVALLNCTAIVNTSNETLTDKNPISDSIHRHAGPELRDELLKLKGCRTGEAKMTEGFDLAARFIIHTVGPKYKAKYRTAAESSLYSCYRNVLQLAKEHAMVSVGFCVISTVKRAYPVEDATHIALRTVRRFLENHGENIETLVFAVSDVEEPVYRKLLPLYYPRSKQEERISLPLLPADIGNSEGEPVVPERQIRIAEKPVNLEDDPEDDSLDSDLGLVGSHAFARMEGDVDKQRKLILQGQMSEVAQQKQHQRNYNRWLCKARAEDLSDIAALKALYQTGVDLCGRTVMVVVGRNIPVMLIDMEKALLYFIHVMDHITVKEYVMVYFHTLTGEHNHLDTDFLKKLYDIVDAKFKKNLRAFYFVHPTFRSKVSTWFFTTFSVSGLKDKVHHIENLQQLFTCVLPEQIDIPPFVLEYDSRVNSPYYSAQSAGL", "length": 504, "header": "sp|Q66HX8-1|GDAP2_DANRE Isoform 1 of Ganglioside-induced differentiation-associated protein 2 OS=Danio rerio OX=7955 GN=gdap2 PE=2 SV=1 CANONICAL=Q66HX8-1" }, "isoforms": [ { "isoform_ac": "A0AC58GDX4-1", "url": "https://www.uniprot.org/uniprotkb/Q66HX8/entry#A0AC58GDX4-1", "sequence": { "sequence": "MDPLGARSQFVEVLNLPTWDQPQGVQDELDGENHYEEEEEEEEDNLTNQLNSVNSPFTFRQDINNKIVLFNGDVALLNCTAIVNTSNETLTDKNPISDSIHRHAGPELRDELLKLKGCRTGEAKMTEGFDLAARFIIHTVGPKYKAKYRTAAESSLYSCYRNVLQLAKEHAMVSVGFCVISTVKRAYPVEDATHIALRTVRRFLENHGENIETLVFAVSDVEEPVYRKLLPLYYPRSKQEERISLPLLPADIGNSEGEPVVPERQIRIAEKPVNLEDDPEDDSLDSDLGLVGSHAFARMEGDVDKQRKLILQGQMSEVAQQKQHQRK", "length": 327, "header": "tr|A0AC58GDX4-1|A0AC58GDX4_DANRE Computationally mapped isoform of Ganglioside-induced differentiation-associated protein 2 isoform X1 OS=Danio rerio OX=7955 GN=gdap2 PE=4 SV=1 CANONICAL=Q66HX8-1" }, "locus": {} }, { "isoform_ac": "Q66HX8-1", "url": "https://www.uniprot.org/uniprotkb/Q66HX8/entry#Q66HX8-1", "sequence": { "sequence": "MDPLGARSQFVEVLNLPTWDQPQGVQDELDGENHYEEEEEEEEDNLTNQLNSVNSPFTFRQDINNKIVLFNGDVALLNCTAIVNTSNETLTDKNPISDSIHRHAGPELRDELLKLKGCRTGEAKMTEGFDLAARFIIHTVGPKYKAKYRTAAESSLYSCYRNVLQLAKEHAMVSVGFCVISTVKRAYPVEDATHIALRTVRRFLENHGENIETLVFAVSDVEEPVYRKLLPLYYPRSKQEERISLPLLPADIGNSEGEPVVPERQIRIAEKPVNLEDDPEDDSLDSDLGLVGSHAFARMEGDVDKQRKLILQGQMSEVAQQKQHQRNYNRWLCKARAEDLSDIAALKALYQTGVDLCGRTVMVVVGRNIPVMLIDMEKALLYFIHVMDHITVKEYVMVYFHTLTGEHNHLDTDFLKKLYDIVDAKFKKNLRAFYFVHPTFRSKVSTWFFTTFSVSGLKDKVHHIENLQQLFTCVLPEQIDIPPFVLEYDSRVNSPYYSAQSAGL", "length": 504, "header": "sp|Q66HX8-1|GDAP2_DANRE Isoform 1 of Ganglioside-induced differentiation-associated protein 2 OS=Danio rerio OX=7955 GN=gdap2 PE=2 SV=1 CANONICAL=Q66HX8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "Q66HX8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q66HX8" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "Q66HX8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=Q66HX8" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:447824", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:447824", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q66H63-1", "protein_name": "Ganglioside-induced differentiation-associated-protein 2", "gene_name": "Gdap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPLGAPSQFVDVDTLVSWGDSYEDEVNSSDSTAEAFQEDSNRSPFLYNRDINGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAISELEEATYQKLLPLYFPRSLKEESQSLPSLPADIGNAEGEPVVPERQIRISEKPGASEDHEEDEDEGLGVDLSFIGSHAFARMEGDIDKQRKLILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDIKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLQQLFSAISPEQIDFPPFVLEYDARENGPYFASYPPSPDL", "length": 497 }, "evidence": [ { "id": "HGNC:18010", "url": "https://alliancegenome.org/gene/HGNC:18010#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-31#orthology", "database": "AGR" }, { "id": "MGI:1338001", "url": "https://alliancegenome.org/gene/MGI:1338001#orthology", "database": "AGR" }, { "id": "RGD:1306050", "url": "https://alliancegenome.org/gene/RGD:1306050#orthology", "database": "AGR" }, { "id": "FB:FBgn0042135", "url": "https://alliancegenome.org/gene/FB:FBgn0042135#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7JUR6-1", "protein_name": "Protein GDAP2 homolog", "gene_name": "Gdap2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLDTNSNVDFKAFESSSSSCPVKLDNLATWGGSQKTDTRLPITDYSNLGGPRHNRSPFPLCKDVNNRFVIWDGDMTTLEVDAITNTSDETLTESNSISERIFAVAGNQLREELSTTVKECRTGDVRITRGYNLPAKYVLHTVAPAYREKFKTAAENTLHCCYRNVLCKAKELNLHTIALCNISAHQKSFPADVAAHIALRTIRRYLDKCTLQVVILCVGSSERGTYEVLAPLYFPRDQLEERSALWQLPKDIGGEFGEPQHPDPDRQIRIIRNPQHSVHMRHHLADDDSDVSPHDMEGNSSDLEYGARDMNGLSLNSYSSGLQAQLQRDLDRQHLLSDRPRTGVYENVISEGVEGIEHQERYERLLRRAQVEDLTEVSGIGCLYQSGVDRLGRPVIVFCGKWFPAQNIDLEKALLYLIKLLDPIVKGDYVISYFHTLTSTNNYPSLHWLREVYSVLPYKYKKNLKAFYIVHPTFWTKMMTWWFTTFMAPAIKAKVHSLPGVEHLYSAITKDQLEIPAYITEYDMATNGLHYFNPVPTAS", "length": 540 }, "evidence": [ { "id": "HGNC:18010", "url": "https://alliancegenome.org/gene/HGNC:18010#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-31#orthology", "database": "AGR" }, { "id": "MGI:1338001", "url": "https://alliancegenome.org/gene/MGI:1338001#orthology", "database": "AGR" }, { "id": "RGD:1306050", "url": "https://alliancegenome.org/gene/RGD:1306050#orthology", "database": "AGR" }, { "id": "FB:FBgn0042135", "url": "https://alliancegenome.org/gene/FB:FBgn0042135#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9DBL2-1", "protein_name": "Ganglioside-induced differentiation-associated protein 2", "gene_name": "Gdap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPLGAPSQFVDVDTLLSWGDSYEDEVDCADSTAEAFQEDASRSPFVYSRDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGENIEKVVFAVSELEEATYQKLLPLYFPRSLKEEIRSLPYLPADIGNAEGEPVVPERQIRISEKPGASEDNEEEDEDEGLGVDLSFIGSHAFARMEGDIDKQRKLILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSDYNHLDSDFLKKLYDVVDIKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLQQLFSAISPEQIDFPPFVLEYDARENGPYFASYPPSPDL", "length": 498 }, "evidence": [ { "id": "HGNC:18010", "url": "https://alliancegenome.org/gene/HGNC:18010#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-31#orthology", "database": "AGR" }, { "id": "MGI:1338001", "url": "https://alliancegenome.org/gene/MGI:1338001#orthology", "database": "AGR" }, { "id": "RGD:1306050", "url": "https://alliancegenome.org/gene/RGD:1306050#orthology", "database": "AGR" }, { "id": "FB:FBgn0042135", "url": "https://alliancegenome.org/gene/FB:FBgn0042135#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NXN4-1", "protein_name": "Ganglioside-induced differentiation-associated protein 2", "gene_name": "GDAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPLGAPSQFVDVDTLPSWGDSCQDELNSSDTTAEIFQEDTVRSPFLYNKDVNGKVVLWKGDVALLNCTAIVNTSNESLTDKNPVSESIFMLAGPDLKEDLQKLKGCRTGEAKLTKGFNLAARFIIHTVGPKYKSRYRTAAESSLYSCYRNVLQLAKEQSMSSVGFCVINSAKRGYPLEDATHIALRTVRRFLEIHGETIEKVVFAVSDLEEGTYQKLLPLYFPRSLKEENRSLPYLPADIGNAEGEPVVPERQIRISEKPGAPEDNQEEEDEGLGVDLSFIGSHAFARMEGDIDKQRKLILQGQLSEAALQKQHQRNYNRWLCQARSEDLSDIASLKALYQTGVDNCGRTVMVVVGRNIPVTLIDMDKALLYFIHVMDHIAVKEYVLVYFHTLTSEYNHLDSDFLKKLYDVVDVKYKRNLKAVYFVHPTFRSKVSTWFFTTFSVSGLKDKIHHVDSLHQLFSAISPEQIDFPPFVLEYDARENGPYYTSYPPSPDL", "length": 497 }, "evidence": [ { "id": "HGNC:18010", "url": "https://alliancegenome.org/gene/HGNC:18010#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-31#orthology", "database": "AGR" }, { "id": "MGI:1338001", "url": "https://alliancegenome.org/gene/MGI:1338001#orthology", "database": "AGR" }, { "id": "RGD:1306050", "url": "https://alliancegenome.org/gene/RGD:1306050#orthology", "database": "AGR" }, { "id": "FB:FBgn0042135", "url": "https://alliancegenome.org/gene/FB:FBgn0042135#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "Q66HX8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HX8" }, { "id": "PRU00490", "database": "PROSITE", "url": "https://prosite.expasy.org/PRU00490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Macro", "eco_id": "ECO_0000255", "start_pos": 54, "end_pos": 234, "start_aa": "Asn", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 }, { "start_pos": 78, "end_pos": 80 }, { "start_pos": 84, "end_pos": 86 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "Q66HY7-1", "uniprot_ac": "Q66HY7", "uniprot_id": "IF4E3_DANRE", "mass": { "chemical_mass": 25403.0, "monoisotopic_mass": 25403.0 }, "refseq": { "ac": "NP_001004589", "name": "eukaryotic translation initiation factor 4E type 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004589" }, "gene_names": [ { "name": "eif4e3", "type": "recommended", "evidence": [ { "id": "Q66HY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q66HY7" } ] }, { "name": "eif4e3", "type": "synonym", "evidence": [ { "id": "NP_001004589", "database": "RefSeq", "url": 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The reference sequence was derived from BC081620.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001004589", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004589" } ] }, { "annotation": "Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis.", "evidence": [ { "database": "UniProtKB", "id": "Q66HY7", "url": "https://www.uniprot.org/uniprotkb/Q66HY7#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "Q66HY7", "url": "https://www.uniprot.org/uniprotkb/Q66HY7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "eif4e3", "url": "https://www.uniprot.org/uniprotkb/Q66HY7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040912-156", "url": 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"sequence": "MAVPAAPNLQLNTARQSSPVNSTENDIHIDERELENITNHVEDGTSLPLHSPWTFWLDRSLPGTTAAECESNLKKIYTVHTVQSFWSVYNNIPPVSCLPLRCSYHLMRGERRPLWEEESNAKGGVWKMKVPKESTLAVWKELLLATIGEQFTDYCASEDEVVGVSVSVREREDVVQVWNGNASFANEANVLGRIYELLPQISFKAVFYKPHEEHHAFEGGRSRH", "length": 224, "header": "sp|Q66HY7-1|IF4E3_DANRE Isoform 1 of Eukaryotic translation initiation factor 4E type 3 OS=Danio rerio OX=7955 GN=eif4e3 PE=2 SV=1 CANONICAL=Q66HY7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:447850", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:447850", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABZ3NNP1-1", "protein_name": "Eukaryotic translation initiation factor 4E type 3", "gene_name": "Eif4e3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RTRGAVRPLLQGARRILVVRATAVQHRREGRGQSQRPGGAHQHRGARPAGQALGIEAVVSDGQVAGDAHAQQQEGRVEAEERGQEGQQLAAQRTRRRPRRGCRAPRSQHDGREAGERAQPVGQAQVEQQVVRRAVQAALPHDEQSEQHVARQAHAQQQAECGQPEAQRGSLGPAAAAARLTSVRHRRRAPPRRPSPLAVGLPGPALRHASSPGPRGCQPAPGRPCPGGSARLGRAAAISVAVRAVGDGHSLRPGRGGLHCRQARSPPHAPRPPPGPPPPPRLLALPPAGPAAAAAAAFATAFAAAAAAAAAAAEPPPLCRSAQRGRRRQSRRGIPRRTGPGWAGGAVATAGRGGRAQDARWRQVAFGPRSLPGATAAECASNLKKIYTVQTVQIFWSVYNNIPPVTSLPLRCSYHLMRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEIIGVSVSVRDREDVVQVWNVNASLVGEATVLEKIHQLLPHISFKAVFYKPHEEHHAFEGGRGKH", "length": 534 }, "evidence": [ { "id": "HGNC:31837", "url": "https://alliancegenome.org/gene/HGNC:31837#orthology", "database": "AGR" }, { "id": "MGI:1914142", "url": "https://alliancegenome.org/gene/MGI:1914142#orthology", "database": "AGR" }, { "id": "RGD:1586185", "url": "https://alliancegenome.org/gene/RGD:1586185#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-156", "url": 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"https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-156#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBB5-1", "protein_name": "Eukaryotic translation initiation factor 4E type 3", "gene_name": "Eif4e3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALPPAAAPPGANEPLDKALSALPPEPGGVPLHSPWTFWLDRSLPGATAAECASNLKKIYTVQTVQIFWSVYNNIPPVTSLPLRCSYHLMRGERRPLWEEESNAKGGVWKMKVPKDSTSTVWKELLLATIGEQFTDCAAADDEIIGVSVSVRDREDVVQVWNVNASLVGEATVLEKIHQLLPHIAFKAVFYKPHEEHHAFEGGRGKH", "length": 207 }, "evidence": [ { "id": "HGNC:31837", "url": "https://alliancegenome.org/gene/HGNC:31837#orthology", "database": "AGR" }, { "id": "MGI:1914142", "url": "https://alliancegenome.org/gene/MGI:1914142#orthology", "database": "AGR" }, { "id": "RGD:1586185", "url": "https://alliancegenome.org/gene/RGD:1586185#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040912-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of translation", "id": "GO:0006417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006417", "evidence": [ { "database": "UniProtKB", "id": "Q66HY7", "url": "https://www.uniprot.org/uniprotkb/Q66HY7" } ], "pmid": "" }, { "name": "translational initiation", "id": "GO:0006413", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006413", "evidence": [ { "database": "UniProtKB", "id": "Q66HY7", "url": "https://www.uniprot.org/uniprotkb/Q66HY7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "eukaryotic translation initiation factor 4F complex", "id": "GO:0016281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016281", "evidence": [ { "database": "UniProtKB", "id": "Q66HY7", "url": "https://www.uniprot.org/uniprotkb/Q66HY7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA 7-methylguanosine cap binding", "id": "GO:0000340", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000340", "evidence": [ { "database": "UniProtKB", "id": "Q66HY7", "url": "https://www.uniprot.org/uniprotkb/Q66HY7" } ], "pmid": "" }, { "name": "translation initiation factor activity", "id": "GO:0003743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003743", "evidence": [ { "database": "UniProtKB", "id": "Q66HY7", "url": "https://www.uniprot.org/uniprotkb/Q66HY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 181, "end_pos": 183 }, { "start_pos": 21, "end_pos": 23 }, { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YYG1-1", "uniprot_ac": "A0A8M6YYG1", "uniprot_id": "A0A8M6YYG1_DANRE", "mass": { "chemical_mass": 499482.0, "monoisotopic_mass": 499482.0 }, "refseq": { "ac": "XP_017211774", "name": "IgGFc-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211774" }, "gene_names": [ { "name": "si:dkey-65b12.6", "type": "recommended", "evidence": [ { "id": "A0A8M6YYG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYG1" } ] }, { "name": "si:dkey-65b12.6", "type": "synonym", "evidence": [ { "id": "XP_017211774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211774" } ] } ], "protein_names": [ { "name": "IgGFc-binding protein", "type": "synonym", "evidence": [ { "id": "XP_017211774", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211774" }, { "id": "A0A8M6YYG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYG1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017211774.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211774" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYG1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-65b12.6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYG1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-329", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-329", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "569718", "url": "https://www.ncbi.nlm.nih.gov/gene/569718", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569718", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569718", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YYG1", "url": "https://www.orthodb.org/?gene=A0A8M6YYG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339:SF373", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339:SF373", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017211774", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211774", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YYG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-329", "url": "https://zfin.org/ZDB-GENE-060526-329", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MERPCFLFCLAVLAVAAVSGCPIGREFITAFMTNYEYGQASLSLTITAHSSPATVKVEIKALSYSQKFDIGRGETKKIVLPSNAEINDEEVSSKTVYISSTADISVVSSNLKDYTGDSSVIFPISQLGRSYVAFTPDTGPPRYQKLVTIVNGNYMNKIEMTFSSKKTLLDSIFGIGTSRKTVSLAPYQVYQLRSEKTLSGTKITSVSPVAVLAGHECSMIIGTCEHVYEQLIPVEFLSNEYLLPAMHQSLSIDTAFVVAPEDNTIVSIFDSRIWFPKKRKLNSGEVLPIDLSKNSKIIQSSKNVMVMYFSSNFPNDEFLTNVIPTSEMSKSWTIYSQDYYDNTLVVVAEAASASTISGSMKWKTFPANNKFVWATKSIGSQRGPITISGDSLMAAYAFGGKIRHGYATTGVCNTAITTTPPPPDPCETMKCRQQEECRKGVCVATSTATCHAVGDPHFKTFDGKLFDFQGTCTYVMVNSTKTQKGLIPFSILTKNNHRGSTRVAYVRSVSVLVYTHTIVVGSQKGVVEFDGENTYLPLSIDGGKIKVNQRGLNVIISTDFGLEVKYDWNMMLYITAPSSYFQTVGGLCGNYNGDRRDEYIDPKGNTLSSIIDFAKTWKVPDNDLFCNDDCNGQCPSCTVSLQEEYKKESNCGVIAKSDGPFVLCHNTVDPRMYVDNCVYDVCINNGIRNFLCNNIQSYVDACMSAGIKITGNWRTLANCPLSCPVNMHYEFCGTACAASCADRSAPDKCTLPCVEGCHCNTGFVRSGAECVPMNKCGCTYKGRYYLAEQSFWSDAKCTEKCVCNSQTGNVECTPTKCKKSQMCDTRNGVKDCYPLSYSTCQAAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADPTLIPFEVLVKNENRGRNLAVAYTKTVSLKVYNYTIVLSKDDPFTVKVNNLFVNLPFEQKDGLFSIFRSGYFGVVKTDFDLTMKFNWDSHVALTLPSTYYGVVGGLCGNWNDNINDDFLTPDKTLAATASIFGTSWKVQDDPGCSDACQGKACPKCDVAERNKDTFTKPCSKITDKQGPFKGCHSKVNPNQFYEDCVYDMCMYGGHSTALCSALTAYTAACQHALGAVESWRTDSFCPASCMDNSHYVVCAAGCSQTCHGLTEPKACVGTSCVESCICDEGFVLSDGVCVSMEQCGCSYEGLYYKMGQVFFPQDKCLQRCTCKENGKVQCDDGFTCKPNEKCQVLNGVQGCFPDGKAVCSVSGFGFYQSFDGRSFSVQGDCEYRLVETALDSDDDLSFFSVLIKQQSSEMVFTRRVELQIEESTITLLPGHIWEVQVDKVKTNLPVTVGEGLIQVYQSGINIVVETDFGLKLTYDTVSVARIEIPSTFKNAVRGLCGNYNGNSADDFLLPGGIQASSEVDFVEAWVSASDKMMCQTGCGANCLKPDKDKQTTAETACSLLITEKGPFSSCYDKIPPQKYFDDCVKDVAQATDKTAHCRHIQNYVASCQTIGISINIWRNTTFCPLTCSKNSHYELCTDTCSSTCASLTKSQRCPLCQEGCQCDDGFLFDGGECKALQNCGCHVDGTFYKSGEAVILGECEETCTCTAGVFTCVPMECKEEEICGVKNGAIGCYSKTIYCPVNMHYEACGTACAPTCADRNPAECALPCVEGCQCNAGFVRSGDECIPVKQCGCAYKGRYYLPGQTFWGEKQCTEKCVCNSQTGNVECAPAKCMNSLVCGVRNGVKDCYPLSYSTCQGAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADPTLIPFEVLVKNENRGRNLAVAYTKSVSLTVYGYTYVLSKESPGKVKVNDLFVKLPFELEDGRLSIFYSGYFGMIKTDFGLTLKFNWDSHVALTLPSTYYGVLGGLCGNWNDNINDEFLTPNNTLAATASIFGTSWKVNDDPGCSDACQGKACASCDVAERNKDTFTKPCSKIIDKQGPFKGCHSKVNPNQFYEDCVYDMCMYGGHSTALCSALTAYTAACQHALGAVESWRTDSFCPTTCKAHSQYEVCAAGCPQTCSGLTEPKSCKGTLCAEGCTCDKGFVLSDGECVAAQQCGCTYKGQYYQLGQVFFPQDKCLQRCTCKENGKVQCDDGFTCKPNEKCQILNGVQGCFPDGKAVCSVSGFGLYQSFDGKSFSVQGDCEYRLVEAVQIQDVKSSFSVLIKQQSSEMIFTRKVEIQLQQSTITLLPGHIWEVQVDKVKTNLPVTVGEGLIQVYQSGINIVVETEFGLKLTYDTVSVARIEIPSTFKNAVRGLCGNYNGNSADDFLLPGGIQASSEVDFVEAWVSASDKMMCQTGCGANCLKPDKDKQTTAETVCSLLITEKGPFSSCYDKIPPQKYFDDCVKDVAQATDKTAHCRHIQNYVASCQAIGISINIWRNTTFCPLTCFKNSHYELCTDTCSSTCASLTKSQRCPLCQEGCQCDDGFLFDGGECKALQDCGCHVDGTFYKSGEAVVLGECKETCTCTAGVFTCVPMECKKEEICDIKEGAVGCYSKKTYCPVNMHYEACGTACAPTCANRDGPEKCALPCVEGCQCNAGFVRSGDECIPVKQCGCAYKGQYYLPGQTFWGEKQCTEKCVCNSQTGNVECAPAKCMNSLVCGVRNGVKDCYPLSYSTCQGAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADPTLIPFEVLVKNENRGRNLAVAYTKSVSLTVYGYTIVLSKESPGKVKVNDLFVKLPFELEDGRLSIFYSGYFGMIKTDFGLTLKFNWDSHVALTLPSTYYGVLGGLCGNWNDNINDEFLTPNNTLAATASIFGTSWKVQDDPGCSDACQGKACPKCDVAERNKDTFTKPCSKITDKQGPFKGCHSKVNPNQFYEDCVYDMCMYGGHSTALCSALTAYTAACQHALGTVESWRTDSFCPTTCKAHSHYEVCAAGCPQTCSGLTEPKSCKGTLCAEGCTCDKGFVLSDGECVAAQQCGCTYKGQYYQLGQVFFPQDKCLQRCTCKENGKVQCDDGFTCKPNEKCQILNGVQGCFPDGKAVCSVSGFGLYQSFDGKSFSVQGDCEYRLVEAVQIQDVKSSFSVLIKQQSSEMVFTRKVEIQLQQSTITLLPGHIWEVQVDKVKTNLPVTVGEGLIQVYQSGINIVVETDFGLKLTYDTVSVARIEIPSTFKNAVRGLCGNYNGNSADDFLLPGGIQASSEVDFVEAWVSASDKMMCQTGCGANCLKPDKDKQTTAETVCSLLITEKGPFSSCYDKIPPQKYFDDCVKDVAQATDKAAHCRHIQNYVASCQAIGISIIVWRNTTFCPLTCFKNSHYELCTDTCSSTCASLTKSQRCPLCQEGCQCDDGFLFDGGECKALQDCGCHVDGTFYKSGEAVVLGECKETCTCTAGVFTCVPMECKKEEICDKKEGAVGCYSKKTYCPVNMHYEACGTACAPTCANRDGPEKCALPCVEGCQCNAGFVRSGDECIPVKQCGCAYKGQYYLPGQTFWGEKQCTEKCVCNSQTGNVECAPAKCLNSLVCGVRNGVKDCYPLSYSTCQGAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADLTLIPFEVLVKNENRGRNLAVAYTKSVSLTVYGYTIVLSKESPGKVKVNDLFVKLPFELEDGRLSIFYSGYFGMIKTDFGLTLKFNWDSHVALTLPSTYYGVLGGLCGNWNDNINDEFLTPNNTLAATASIFGTSWKVKDDPGCSDACQGKACASCDVAERNKDTFTKPCSKITDKQGPFKGCHSKVNPNLFYEDCVYDMCMYGGHSTALCSALTAYTAACQHALGTVESWRTDSFCPTTCKAHSHYEVCAAGCPQTCSGLTEPKSCKGTLCAEGCTCDKGFVLSDGECVAAQQCGCTYKGQYYQLGQVFFPQDKCLQRCTCKENGKVQCDDGFTCKPNEKCQILNGVQGCFPDGKAVCSVSGFGLYQSFDGKSFSVQGDCEYRLVEAVQIQDVKSSFSVLIKQQSSEMVFTRKVEIQLQQSTITLLPGHIWEVQVDKVKTNLPVTVGEGLIQVYQSGINIVVETDFGLKLTYDTVSVARIEIPSTFKNAVRGLCGNYNGNSADDFLLPDGIQTSSVEYFAEAWVSPSDKMMCQTGCGANCLKPDKDKQTTAEIACSLLITEKGPFSSCYDKIPPQKYFDDCVKDVAQATDKTAHCRHIQNYVASCQAIGISIIVWRNITFCPIMCLANSHYELCTDTCSSTCASLTNSQKCPPCQEGCQCDDGFLFDGGECKAFQDCGCQVGGRFYKSDETVVRGECEETCLCKAGLFTCEPLKCDADQICDNIEGITGCYKKDPCSKQQCREQEYCTVKDNKALCIAKSKASCIAKGDPHYKTFDGNHFSFQGTCTYTLVKTSGKDQTLTPFSIINKNEFTKGTRGSFVKSATITVRGHDITFIQGSRNHVTVDGVVSHLPVILNTEGISIILSRNVGVLQTDFGLEVMFNWADTIMVTLSSSYYNNVVGMCGTYSNKLDDDYITPNGNRITDITEWATSWSVPETNSNCWHFPPCSDEKKLLYSGQSYCGLIENVTGPFAQCHDIISKRRFAADCLFQMCLNEGSQKAFCNAFNNYVSACALVNADVSPDWKKLANC", "length": 4571, "header": "tr|A0A8M6YYG1-1|A0A8M6YYG1_DANRE Isoform 1 of IgGFc-binding protein OS=Danio rerio OX=7955 GN=si:dkey-65b12.6 PE=1 SV=2 CANONICAL=A0A8M6YYG1-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YYG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYG1/entry#A0A8M6YYG1-1", "sequence": { "sequence": "MERPCFLFCLAVLAVAAVSGCPIGREFITAFMTNYEYGQASLSLTITAHSSPATVKVEIKALSYSQKFDIGRGETKKIVLPSNAEINDEEVSSKTVYISSTADISVVSSNLKDYTGDSSVIFPISQLGRSYVAFTPDTGPPRYQKLVTIVNGNYMNKIEMTFSSKKTLLDSIFGIGTSRKTVSLAPYQVYQLRSEKTLSGTKITSVSPVAVLAGHECSMIIGTCEHVYEQLIPVEFLSNEYLLPAMHQSLSIDTAFVVAPEDNTIVSIFDSRIWFPKKRKLNSGEVLPIDLSKNSKIIQSSKNVMVMYFSSNFPNDEFLTNVIPTSEMSKSWTIYSQDYYDNTLVVVAEAASASTISGSMKWKTFPANNKFVWATKSIGSQRGPITISGDSLMAAYAFGGKIRHGYATTGVCNTAITTTPPPPDPCETMKCRQQEECRKGVCVATSTATCHAVGDPHFKTFDGKLFDFQGTCTYVMVNSTKTQKGLIPFSILTKNNHRGSTRVAYVRSVSVLVYTHTIVVGSQKGVVEFDGENTYLPLSIDGGKIKVNQRGLNVIISTDFGLEVKYDWNMMLYITAPSSYFQTVGGLCGNYNGDRRDEYIDPKGNTLSSIIDFAKTWKVPDNDLFCNDDCNGQCPSCTVSLQEEYKKESNCGVIAKSDGPFVLCHNTVDPRMYVDNCVYDVCINNGIRNFLCNNIQSYVDACMSAGIKITGNWRTLANCPLSCPVNMHYEFCGTACAASCADRSAPDKCTLPCVEGCHCNTGFVRSGAECVPMNKCGCTYKGRYYLAEQSFWSDAKCTEKCVCNSQTGNVECTPTKCKKSQMCDTRNGVKDCYPLSYSTCQAAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADPTLIPFEVLVKNENRGRNLAVAYTKTVSLKVYNYTIVLSKDDPFTVKVNNLFVNLPFEQKDGLFSIFRSGYFGVVKTDFDLTMKFNWDSHVALTLPSTYYGVVGGLCGNWNDNINDDFLTPDKTLAATASIFGTSWKVQDDPGCSDACQGKACPKCDVAERNKDTFTKPCSKITDKQGPFKGCHSKVNPNQFYEDCVYDMCMYGGHSTALCSALTAYTAACQHALGAVESWRTDSFCPASCMDNSHYVVCAAGCSQTCHGLTEPKACVGTSCVESCICDEGFVLSDGVCVSMEQCGCSYEGLYYKMGQVFFPQDKCLQRCTCKENGKVQCDDGFTCKPNEKCQVLNGVQGCFPDGKAVCSVSGFGFYQSFDGRSFSVQGDCEYRLVETALDSDDDLSFFSVLIKQQSSEMVFTRRVELQIEESTITLLPGHIWEVQVDKVKTNLPVTVGEGLIQVYQSGINIVVETDFGLKLTYDTVSVARIEIPSTFKNAVRGLCGNYNGNSADDFLLPGGIQASSEVDFVEAWVSASDKMMCQTGCGANCLKPDKDKQTTAETACSLLITEKGPFSSCYDKIPPQKYFDDCVKDVAQATDKTAHCRHIQNYVASCQTIGISINIWRNTTFCPLTCSKNSHYELCTDTCSSTCASLTKSQRCPLCQEGCQCDDGFLFDGGECKALQNCGCHVDGTFYKSGEAVILGECEETCTCTAGVFTCVPMECKEEEICGVKNGAIGCYSKTIYCPVNMHYEACGTACAPTCADRNPAECALPCVEGCQCNAGFVRSGDECIPVKQCGCAYKGRYYLPGQTFWGEKQCTEKCVCNSQTGNVECAPAKCMNSLVCGVRNGVKDCYPLSYSTCQGAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADPTLIPFEVLVKNENRGRNLAVAYTKSVSLTVYGYTYVLSKESPGKVKVNDLFVKLPFELEDGRLSIFYSGYFGMIKTDFGLTLKFNWDSHVALTLPSTYYGVLGGLCGNWNDNINDEFLTPNNTLAATASIFGTSWKVNDDPGCSDACQGKACASCDVAERNKDTFTKPCSKIIDKQGPFKGCHSKVNPNQFYEDCVYDMCMYGGHSTALCSALTAYTAACQHALGAVESWRTDSFCPTTCKAHSQYEVCAAGCPQTCSGLTEPKSCKGTLCAEGCTCDKGFVLSDGECVAAQQCGCTYKGQYYQLGQVFFPQDKCLQRCTCKENGKVQCDDGFTCKPNEKCQILNGVQGCFPDGKAVCSVSGFGLYQSFDGKSFSVQGDCEYRLVEAVQIQDVKSSFSVLIKQQSSEMIFTRKVEIQLQQSTITLLPGHIWEVQVDKVKTNLPVTVGEGLIQVYQSGINIVVETEFGLKLTYDTVSVARIEIPSTFKNAVRGLCGNYNGNSADDFLLPGGIQASSEVDFVEAWVSASDKMMCQTGCGANCLKPDKDKQTTAETVCSLLITEKGPFSSCYDKIPPQKYFDDCVKDVAQATDKTAHCRHIQNYVASCQAIGISINIWRNTTFCPLTCFKNSHYELCTDTCSSTCASLTKSQRCPLCQEGCQCDDGFLFDGGECKALQDCGCHVDGTFYKSGEAVVLGECKETCTCTAGVFTCVPMECKKEEICDIKEGAVGCYSKKTYCPVNMHYEACGTACAPTCANRDGPEKCALPCVEGCQCNAGFVRSGDECIPVKQCGCAYKGQYYLPGQTFWGEKQCTEKCVCNSQTGNVECAPAKCMNSLVCGVRNGVKDCYPLSYSTCQGAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADPTLIPFEVLVKNENRGRNLAVAYTKSVSLTVYGYTIVLSKESPGKVKVNDLFVKLPFELEDGRLSIFYSGYFGMIKTDFGLTLKFNWDSHVALTLPSTYYGVLGGLCGNWNDNINDEFLTPNNTLAATASIFGTSWKVQDDPGCSDACQGKACPKCDVAERNKDTFTKPCSKITDKQGPFKGCHSKVNPNQFYEDCVYDMCMYGGHSTALCSALTAYTAACQHALGTVESWRTDSFCPTTCKAHSHYEVCAAGCPQTCSGLTEPKSCKGTLCAEGCTCDKGFVLSDGECVAAQQCGCTYKGQYYQLGQVFFPQDKCLQRCTCKENGKVQCDDGFTCKPNEKCQILNGVQGCFPDGKAVCSVSGFGLYQSFDGKSFSVQGDCEYRLVEAVQIQDVKSSFSVLIKQQSSEMVFTRKVEIQLQQSTITLLPGHIWEVQVDKVKTNLPVTVGEGLIQVYQSGINIVVETDFGLKLTYDTVSVARIEIPSTFKNAVRGLCGNYNGNSADDFLLPGGIQASSEVDFVEAWVSASDKMMCQTGCGANCLKPDKDKQTTAETVCSLLITEKGPFSSCYDKIPPQKYFDDCVKDVAQATDKAAHCRHIQNYVASCQAIGISIIVWRNTTFCPLTCFKNSHYELCTDTCSSTCASLTKSQRCPLCQEGCQCDDGFLFDGGECKALQDCGCHVDGTFYKSGEAVVLGECKETCTCTAGVFTCVPMECKKEEICDKKEGAVGCYSKKTYCPVNMHYEACGTACAPTCANRDGPEKCALPCVEGCQCNAGFVRSGDECIPVKQCGCAYKGQYYLPGQTFWGEKQCTEKCVCNSQTGNVECAPAKCLNSLVCGVRNGVKDCYPLSYSTCQGAGDPHFRTFDGKAFDFQGTCTYYLSKLLNTADLTLIPFEVLVKNENRGRNLAVAYTKSVSLTVYGYTIVLSKESPGKVKVNDLFVKLPFELEDGRLSIFYSGYFGMIKTDFGLTLKFNWDSHVALTLPSTYYGVLGGLCGNWNDNINDEFLTPNNTLAATASIFGTSWKVKDDPGCSDACQGKACASCDVAERNKDTFTKPCSKITDKQGPFKGCHSKVNPNLFYEDCVYDMCMYGGHSTALCSALTAYTAACQHALGTVESWRTDSFCPTTCKAHSHYEVCAAGCPQTCSGLTEPKSCKGTLCAEGCTCDKGFVLSDGECVAAQQCGCTYKGQYYQLGQVFFPQDKCLQRCTCKENGKVQCDDGFTCKPNEKCQILNGVQGCFPDGKAVCSVSGFGLYQSFDGKSFSVQGDCEYRLVEAVQIQDVKSSFSVLIKQQSSEMVFTRKVEIQLQQSTITLLPGHIWEVQVDKVKTNLPVTVGEGLIQVYQSGINIVVETDFGLKLTYDTVSVARIEIPSTFKNAVRGLCGNYNGNSADDFLLPDGIQTSSVEYFAEAWVSPSDKMMCQTGCGANCLKPDKDKQTTAEIACSLLITEKGPFSSCYDKIPPQKYFDDCVKDVAQATDKTAHCRHIQNYVASCQAIGISIIVWRNITFCPIMCLANSHYELCTDTCSSTCASLTNSQKCPPCQEGCQCDDGFLFDGGECKAFQDCGCQVGGRFYKSDETVVRGECEETCLCKAGLFTCEPLKCDADQICDNIEGITGCYKKDPCSKQQCREQEYCTVKDNKALCIAKSKASCIAKGDPHYKTFDGNHFSFQGTCTYTLVKTSGKDQTLTPFSIINKNEFTKGTRGSFVKSATITVRGHDITFIQGSRNHVTVDGVVSHLPVILNTEGISIILSRNVGVLQTDFGLEVMFNWADTIMVTLSSSYYNNVVGMCGTYSNKLDDDYITPNGNRITDITEWATSWSVPETNSNCWHFPPCSDEKKLLYSGQSYCGLIENVTGPFAQCHDIISKRRFAADCLFQMCLNEGSQKAFCNAFNNYVSACALVNADVSPDWKKLANC", "length": 4571, "header": "tr|A0A8M6YYG1-1|A0A8M6YYG1_DANRE Isoform 1 of IgGFc-binding protein OS=Danio rerio OX=7955 GN=si:dkey-65b12.6 PE=1 SV=2 CANONICAL=A0A8M6YYG1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:569718", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569718", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZQD3-1", "protein_name": "Mucin-2", "gene_name": "Fcgbp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPGHGSSFESTLDKKKKISSSLALVTFQVLSSHRGSVAPLSTTGKGERESARHHRVFCGTAWADMAAIWRSNYGMGSPWSWWALWAGAILLWARLTPTEASCQGVQCASGQRCQMVSGKARCVAESTAVCRAQGDPHYTTFDGRRYDMMGSCSYTMAELCGSDETLPAFSVEAKNEHRGSRQVSYVGLVTVYAYSHSVSMVRGETGFIRIDNQRSRLPASLSEGRLRVYQSGTRGIIELDFGLVISYDWDSQLTLSLPKRFQDQVCGLCGNYNGDPADDFLTPDLEQAPNALEFANSWKLDDGDYLCDDGCHNSCPSCTPGQMQHYKGDRLCGMLALSTGPFSACHELLDPKPFLEDCVFDLCVTGGERLSLCRSLSAYAQACVELGVTLENWRQPSNCPMSCPANSCYDPCSPACPASCNSEALPSNCSSRPCVEGCVCLPGFVASGGDCVPVSSCGCTYQGRPLAPGQEVFADDQCQRRCTCDGATQKVTCRDTSGCPSGEHCNVQNGLLGCYPDNFASCQASGDPHYVSFDGKRFDFMGTCTYLLVGSCGQNAALPAFKVLVENEHRGSQTVSYTRAVRVVAHGVEVAVRRENPGRVLVDGVLQYLPFQAAGGKVRVYRQGNDAVVSTDFGLTVTYNWDAHVTAKVPNSYAKAVCGLCGNFNGNPDDDLALKGGGQANNVLDFGNSWQEEIIPGCGATTPGDCPQLDSLVTQQTQSKKECGILADPEGPFRECHKLLNPQGAIRDCVYDLCLLPGQSGPLCEALAAYAAECQAAGGTVHPWRSEKLCPLTCPPNSHYELCSYGCPLSCGDLPVPGGCGSECRESCVCDEGFALSGESCVPLASCGCVYQGAYHSPGETFYPGPGCESLCHCEEGGLVSCEPSSCGPHEACQPSNGVLGCVAVGTTTCQASGDPHYITFDGRRFDFMGTCVYVLAQTCGTRPGLHQFTVLQENEPWGNGKVSVTKVITVLVANYTLRLEQNQWKVKVNGVDMKLPVVLDGGKIRVSQHGSDAVIETDFGLRVAYDLVYSVRVTIPGNYYQQMCGLCGDYNGDPKDDFQKPDGSQATNPSDFGNSWEEAVPDSPCAPVPPCTGDDCNPACSPELENKYSGEKFCGLLTNPTGPLAACHKLLDPQGPLKDCVFDLCLGGGNQSILCNNIHAYVSACQEAGGQVEPWRTETFCPMKCPPHSHYEVCADTCSLGCWALSTPQKCPEVCAEGCECDSGFLYNGKACVPIQECGCYHNGVYYEPEESVLIENCQQHCVCHPGTGMVCQDHSCKPGEVCEPSGGVLTCITKDPCHGITCRPQETCKVEGGEGVCVPNYHATCWLWGDPHYNSFDGWSYDFQGTCNYLLAGTICPGINAEGLTPFTVTTKNENRGNPAVSYVRLVTVTTLNTNISIHKNEIGKVRVNGALVTLPVYLAGGRISVINGGSKAVLETDFGLQVTYDWNWRVEVTLPSSYHSAVCGLCGNMDKKPENDKVFPNGTVAPSIPAWGGSWQVPGWDPLCWNECQGSCPTCPEDRVEEYEGPGFCGPLAPGTGGPFASCHSHVPPESFFKGCVLDVCLGGGNKDILCQALAAYAAACQAAGIKIEDWRTQAGCEIPCPDNSHYELCGPRCPASCPPPAQHTPPTACDGPCVEGCQCDQGFVLSADQCVPLDGGCGCWVNGTYHEAGTEFWTDTTCSKRCHCGPGGDSLICKSASCGLGEECALLPSGEIGCQPTSIAECEAWGDPHYTTLDGHRFDFQGTCEYLLSAPCHAPPPGIEYFNVTVANEHRGSQAVSYTRSVTLHIYGLSLTLSAQWPRQLQVNGEFVALPFHLDQKLSVYISGADVVVNTASGLSLAFDGNSFVRLRVPAAYAGSLCGLCGNYNKNPNDDLTAVDGKPEGWKVGGAPGCDQCQPEPCPQPCTPEQQEPFRGPDACGIITAPEGPLAPCHSLVPPTKYFEACLLDACQVQGHPGGLCPAIATYVAACQAAGAQLGEWRKPDFCPLQCPANSHYQLCGDSCPVSCPSLSAPEGCETTCREGCVCDSGFVLSGDTCVPVGQCGCLYNGRYYVLGATFYPGPECERLCECGPGGQVTCQEGADCEPYEECRVENGVQACHPTGCGHCLANGGVHYVTLDGRVYDLHGSCSYVLAGVCRPKPGEEEFSIVLEKDSAGEPQRVVVTVADQVVVLARGPQVTVDGEAVALPVATAHVSVTAEGRNVVLQTNKGMKVLFDGDAHILMSIPSSFRGRICGLCGNFNGNWSDDFVLPGGAVAPNVDAFGAAWRAPSSSLGCSEGCGPQGCPVCLAEETEAYEKNDACGKIRDPKGPFATCHKVLSPLEYFRQCVYDMCAHKGDKAYLCRSLAAYTAACQASGAAVKPWRTDSFCPLQCPAHSHYSVCTRSCQGSCAALSGLTGCTTRCFEGCECDDHFLLSQGVCIPAQDCGCVHNGQYVPVNSSLMSSDCSELCYCSETTGLTCRAAGCPSGQVCEIQAGVRQCRAAHGLCSLSVGANLTTFDGALNTISSPGVYELSSRCPGFQKNVPWYRLLADVQPCLNNDKIVSKVHIFFQDGMVTVIPSKGAWVNGLRVDLPATVLTSVSVKKMPDGSMFVHQKAGVQVWLGKDGHLDVMVGDDHAAVLCGVCGNFDGDQTNDAHGSQGKTTIEKWRAQDFSPCPN", "length": 2658 }, "evidence": [ { "id": "HGNC:13572", "url": "https://alliancegenome.org/gene/HGNC:13572#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PVG8-1", "protein_name": "Mucin-2", "gene_name": "Fcgbpl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSLWSCWALWAGATLLWALLTPAEASCQGIQCAPGQRCQMVSGKAKCLAESTAVCRAQGDPHYTTFDGHRYDMMGTCTYTMAELRSSKDSLLAFKVDAKNEHRSSNKVSYVRLVTVHAYNHTVSLIYGEVGLAKIDYQYSSLPVSLSEGLLRVHQSGTRGVLELDFGLVVTYDWDGQLTLSLPKRFQDQVSGLCGNYNGDPADDFLTPDGKQAPDVLNFTKSWKVNDQDLLCDDGCYGNCPSCIPSQAQLFKKDLFCGMLTLPSGPFADCHQFLDPKPFLEECVYDMCVTGGERLTLCRGLNAYAQACVDLGISVREWRSRTNCPLTCPANSHYELCSPACPPSCNSEARPTNCSSRPCVEGCVCLPGFVASRGLCMPVSSCGCIFQDRLLAPGQEVYADEKCHLRCTCDGATQKVICRNTTGCLPKEHCGVQNGSFGCFPEYFRICRASGDPHYMSLDERIFNFMGTCTYLFTASCGQHPSLPDFKVFIENERRGSQSVSFVRSVKLEALGIKLEVRREYQGKVLVDGILHYLPFQALGGKLVVFRQGKYAILRTNFSLSVSYNWDTHVTAKVPSNYFNSVCGLCGNFNGDPRDDLGKQIRAEAIDPRDFGKKWLVSSHLGCRTDEQHLCPDFNKGLVSNITQNCRIFTNISGHFKHCWRVPAYNSAYIECAYDCCRMPGQTKPLCDTLATYTAICQSSGVIVYPWRTETLCPMTCPPHSHYELCQRGCPLTCGDQPVPGGCGSDCYESCVCDEGYVLSGEACVPLASCGCVYQGIYHAPGDEFYPGPECNSLCHCDKGGLVSCQPSHCSPHEVCKVLDGILRCVGEGSATCQVSGASHYTTFDGRHFDFMGTCVHVLAQTCWTRPGLKPFTILQENAVQGNKQVSVTKKITIEVANYTLQLEQNQWKVKVNGVDMKLPVLLDEDRVQAFRHGTDMVIETKFGLLVSYDLKYSVRVKVPHNYYKHMCGLCGDYNDDPKNDFQKSDGSQAASSNELGDSWEKAVPGSSCTPRPSCKPGQACSPKCYPTLEKKYRGKEFCGLITSPTGPLAACHKLLDPQGPLQSCVFDLCLGGGNQSILCSSIHAYVSACQAAGGTVKPWRNQTFCPMECPPHSHYEVCADTCSLDCSAITTPMQCLTPCSEGCECDTDFLQSITTCVPMEKCGCHYNGVYYEPEESVLIENCQQHCVCQPGKGMMCQDHSCKPGQVCEPSGGVLTCVTKDPCQGVTCRSQETCTEKDGKGVCRANYESKCWVWGDPHYHSFDGLNTNFHGTCSYLMAGTGCPGTGAEGLTPFSVITKHESQSDPKVSYVRKVTVKTYNTSITIHEKKTGRVQVNGVFMALPVYLAGGRISVINGGSKAVLETNFGLQVTYNWKWRVHVTLPSSYYGAVCGLCGNMDKNPQNDQVFPNGTMAPSIPTWGGSWQVPGWDPLCWNECQGSCPTCPEDRVEEYRGPGFCGPLDHDTVGPFTSCHAHVPPESFFEGCVLDVCLGGQVKDILCQALADYAAACQAAGIKIEDWRTQAGCEITCPVNSHYELCGPPCPASCPPPARHTAPTACDGPCVEGCQCDKGFVLSADQCVPLDGGCGCWVNGTYYEAGTEFWADTTCSKRCHCGPGGDSLVCKPASCGLGEECALLASGEIGCQPISIAECQILGDPTYITLDGHRFDFQGTCEYLLSAPCHAPPTGTEYFNVTVVNEHRCSQAVSYTRSITLRIYGLSLTLSAHWPKNLLVDGEMVKLPFQLQSRLLVHLSGMGLVVHTSWGLSLTFDGNSFMRLRVPAAYAGTLCGLCGNYNKNPNDDLTAVGGKPEGWKVGGFPDCDQCQLRTCPKPCTPEERKRFGGPNACGIITAPEGPLAPCHSFVPPTQYFEACLLDTCQVQGHSGGLCPAIATYVAACQDARVRLREWRKPDFCPLQCPAHSHYQLCGDSCPVSCPSLSAPVGCETICREGCVCDAGFVLSGDTCVPVGQCGCLHQGRYYALGATFYPGYECEWFCECGPDDQVTCRIETCGIHEECRIEDGIRSCHPKSSKLMLVLHGTHYATPDGLVYDLYGSCSYILAQVCFPKHGEEAFSIVLEKDLAGNPQRVVVTVAGQVVVLAKGPQVTVDSEVVALPMVVGSIYITAENRNVFLQTKSGLKLLFDGDDHILISIPSPFRGRLCGLCGNFNGNQSDDFVLPSGVVAPNVEAFGAAWRAPGSSLGCGEGCGPQGCPVCSAEKRELYEENDACGKIRDPQGPFAACHKALNHSEYFHQCVFDLCTHHGDRDYLCRSLAAYTAACQAAGAAVKPWRTDSICPAECPAHSHYSICTHSCQGSCAAISGFTGCTTQCFEGCECDDHFLLSQGVCIPAQDCGCFYNDQYMPVDSSLMSSDCSERCFCSPNNGLTCHEAGCPSGRVCEIQAGVRGCWPAKGLCTFSVGGNLITFDGAFNPISSPGVYELSSRCPGLLKNVPWYRVLADVQPCHDNDKIVSKVHIFFQDGMVTVIPSKGTWVNGLRVDLPATVLTSVSVRRMPDGSMLVHQKAGVTVWLGKDGLLDVMVGDNHAAMLCGACGNFDGDRNNDVHKNQKTISIETWRAQDFSPCAN", "length": 2581 }, "evidence": [ { "id": "HGNC:13572", "url": "https://alliancegenome.org/gene/HGNC:13572#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9C6-1", "protein_name": "Mucin-2", "gene_name": "Fcgbp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSPWKWWALWAGATLLWALLTPAEASCQGIQCASGQRCQMVSGKARCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMAELCGSDETLPAFSVEAKNEHRGSRQVSYVGLVTVYAYSHSVSLVRGEIGFVRIDNQRSRLPASLSEGRLRVHKSGTRGVIEMDFGLVVTYDWDGQLTLSLPKRFQDQVCGLCGNYNGDPADDFLTPDLDQAPDALEFANSWKLDDGDYLCDDGCHNSCPSCTPGQTQHYKGDRLCGMLTLSTGPFSACHEFLDPKPFLDDCVFDLCVTGGERLSLCRSLSAYAQACVELGVTLENWRLPASCPMSCPANSCYDPCSPACPPSCNSEAVPTNCSSRPCVEGCVCLPGFVASGGDCVPVSSCGCIYQGRLLAPGQEVFDDDRCRRRCTCDGATQKVTCRDTTGCPSGERCNVQNGLLGCYPDNFASCQASGDPHYVSFDGKRFDFMGTCTYLLVGSCGQNAALPAFKVLVENEHRGSQTVSYTRAVRVVAHGVEVAVRRENPGRVLIDGVLQYLPFQAAGGKIQVYRQGNDAIVSIDFGLTVTYNWDAHVTAKVPSSYAKDVCGLCGNFNGNPDDDLALKGGGQASNVLDFGNSWQEEIIPGCGATEPGDCPQLDSLVTQQIQDKKECGILADPEGPFRECHKLLNPQGAIRDCVYDLCLLPGQSGPLCDALAAYAAACQAAGGTVHPWRSEELCPLTCPPNSHYEQCSYGCPLSCGDLPVQGGCGSECREGCVCNEGFALSGESCVPLASCGCVHEGAYHAPGETFYPGPGCDSLCHCEEGGLVSCEPSSCGPQEACQPSNGVLGCVAVGTTTCQASGDPHYVTFDGRRFDFMGTCVYVLAQTCGNRPGLHQFTVLQENEAWGNGKVSVTKVITVLVANYTLRLEQSQWKVKVNGVDTKLPVMLDGGKIRVSQHGSDVVIETDFGLRVAYDLVYYVRVTIPGNYYKQMCGLCGDYNGDPKDDFQKPDGSQTTDPSDFGNSWEEAVPDSPCAPVPPCTGDDCDTECSPELQDKYHGEQFCGLLTSPTGPLAACHKLLDPQGPLQDCVFDLCLGGGNQSILCNIIHAYVSACQAAGGQVEPWRTETFCPMECPPHSHYEVCADTCSLGCWALNTPQQCPEGCAEGCECDSGFLYNGKACVPIEQCGCYHNGVYYEPEESVLIENCQQHCVCQPGKGMMCQDHSCKPGQVCEPSGGVLTCVTKDPCHGITCRPQETCKVQGGEGVCVPNYNSTCWLWGDPHYNSFDGWSFDFQGTCNYLLAGTLCPGVNAEGLTPFTVTTKNENRGSPAVSYVRQVTVTTLNTNISIHKNEIGKVRVNGVLMALPVYLAGGRISVINGGSKAVLETDFGLQVTYDWNWRVDVTLPSSYHGAVCGLCGNMDKNHQNDQVFPNGTMAPSIPTWGGSWQVPGWDPLCWHECQGSCPTCPEDRVEEYEGPGFCGPLAPGTGSPFTSCHAHVPPESFFKGCVLDVCLGGGSKDILCQALAAYAAACQAAGIKIEDWRTQAGCEITCPDNSHYELCGPPCPASCPPPARHTAPTVCDGPCVEGCQCDEGFVLSADQCVPLDGGCGCWVNGTYYEAGTEFWADTTCSKRCHCGPGGDSLVCKPASCGLGEECALLPSGEIGCQPTSITECQAWGDPHYTTLDGHRFDFQGTCEYLLSAPCHEPPTGTEYFNVTVANEHRGSQAVSYTRSVTLQIYGLSLTLSAQWPRKLQVNGEFVALPFHLDQKLSVYISGADVVVNTASGVSLAFDGDSFVRLRVPAAYAGTLCGLCGNYNKNPNDDLTAVGGKPEGWKVGGAPGCDQCEPEPCPKPCTPEEQEPFRGPDACGIITAPEGPLAPCHSLVPPTQYFEACLLDACQVQGHPGGLCPAIATYVAACQAAGAQLGEWRKPDFCPLQCPAHSHYQLCGDSCPVSCPSLSAPVGCETICREGCVCDAGFVLSGDTCVPVGQCGCLYQGRYYVLGATFYPGPECERLCECGPDGQVTCQEGADCEPYEECRIENGVQACHPTGCGHCLANGGLHYVTLDGRVYDLHGSCSYVLASVCHPKPGDEEFSIVLEKNSAGDPQRVVVTVAGQVVGLARGPQVTVDGEVVTLPVATGHVSVTAEGRNIVLQTNKGMKVLFDGDAHILMSIPSSFRGRLCGLCGNFNGNWSDDFVLPSGAVAPNVEAFGTAWRAPGSSLGCGEGCGPQGCPVCLAEETQAYEKNDACGKIRDPHGPFAACHKVLSPLEYFRQCVYDMCAHKGDKAYLCRSLAAYTAACQAAGAAVKPWRTDSVCPLQCPAHSHYSICTRSCQGSCAALSGLTGCTTRCFEGCECDDHFLLSHGVCIPAQDCGCVHNGQYMPVNSSLMSSDCSERCFCSPNNGLTCHEAGCPSGHVCEIQAGVRECQAARGLCSISVGANLTTFDGAHNAISSPGVYELSSRCPGLQKNVPWYRVLADVQPCHNNDKIVSKVHIFFQDGLVTVIPSKGAWVNGLRVDLPATVLTSVSVRRMPDGSMLVHQKAGVTVWLGKDGLLDVMVGDDLAAMLCGACGNFDGDQTNDAYGSQGKTPIEKWRAQDFSPCSN", "length": 2583 }, "evidence": [ { "id": "HGNC:13572", "url": "https://alliancegenome.org/gene/HGNC:13572#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7EZQ4-1", "protein_name": "Mucin-2", "gene_name": "Fcgbpl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPPWSWWALWAGASLLWARLAPTEASCQGVQCPPGQRCQMESGKARCVPEPRAVCRAQGDPHYTTFDGRRYDMMGTCTYVLTELRSTKDSLLAFKVEAKNKHRSSNKVSYVRLVTVHAYDYTVSLMYGEIGFAKINYQYSVLPVSLSKGRLRVYQSGTRGIIELDFGLVVTYDWDCLLSLSLPKRFQDQVSGLCGNYNGDPADDFLTPDGKQASDVLNFTKSWKVQDKDLLCDDGCYGNCPSCIPSQAEIFKKDPFCGMLILPSGPFADCHKFLDPKPFLEECVYDMCVTGGERLTLCHGLNAYALACVDMGISVREWRSRTNCPLTCPANSRYELCSPACPASCNSEALPTNCSSRPCVEGCVCFPGFVASRGLCMPVSSCGCTFQDRLLAPGQEVYADEKCHLRCTCDADFQEVICRNTSGCLLHEHCGVRNGSFGCSPEYFRICRASGDPHYMSLDERIFNFMGTCTYLFTASCGQHPSLPDFKVFIENERRGSQSVSFVRSVKLEAFGISLEVRREYQGKVLMNGILHYLPFQALGGKLVVFRQGKYAILRTNFSLTISYNWDTHVTAKVPSNYFKGVCGLCGNFNGDPRDDLGVQIRGEALDPRDFGKKWLVSSHPGCRTDEQLLCPSFKKEIVKSITKKCHILGNISGEFRHCWRVPAFNSALIECMYDCCRMPGQTKPLCDSLATYTSICQSSGVAVLPWRTEDLCPMNCPPHSHYELCQRGCPLTCGDQPVPGGCGSDCYESCVCDEGFVLSGEICIPLSSCGCVYQGIYHAPGDDFYPGPECNSLCHCNKGGLVSCQPSYCGPHEVCKVIDGILRCVGVGSATCHVSGASHYTTFDGRRFDFMGTCVYVLAQTCWTQPGLQPFTILQENVVRGDKQISVTKMITIEVANYTLQLEQNQWKVKVNAVYMKMPVSLDGERVQAFLHGTDVVIKTKFGLLVSYDLKYSVRVTVPRNYYKHMCGLCGDYNNNPKNDFQKSDGSQAVSPGELGKSWEKTVPGSSCTPRPACKPGQDCTPKCYPTLERKYSGNEFCGLLTNPTGPLAACHKLLDPQGPLQNCVFDLCLGGGNLSILCNSIHAYVSACQEAGGTVKPWRNQTFCPMECSPHSHYEVCADTCSLDCSTITTPIKCLKTCSEGCECDTDFLQSITACVPMEKCGCHHNGVYYEPEESVLIENCQQHCVCHPGTGMVCQDHSCKPGEVCKPSRGVLTCINKDPCKGVTCRSQETCTERDGKGVCTANYESKCWVWGDPHYHSFDGLNTNFHGTCSYQLAGTGCPGISAEGLTPFNVVTKHESQSNPTVSNVKKVTVTTYNTSITIHKKKIGRVQVNGVLMALPVYLAEGRISVVHGGTKAVLETDFGLQVTYDWTWRVQVTLPSSYYGAVCGLCGNMDKNPKNDQVFPNGTVALSIPAWGGSWQVPGWDPLCWNECQGSCPTCPEDRVEEYEGPGFCGPLSPDTVGPFASCHSHVPPESFFKGCVLDLCLGGQVKDILCQALAAYAEACQAHGIKIQDWRTQAGCEISCPDNSHYELCGPRCPVSCPPPTRHNPPTACDGPCVEGCQCDLGFVLSADQCVPLDGGCGCWVNGTYHEAGTEFWTDTTCSKRCHCGPGGDSLICKSASCGLGEECALLPSGEIGCQPTSIAECQILGDPRYITLDGHRFDFQGTCEYLLSAPCHAPPPGIEYFNVTVANEHRGSQAVSYTRSVTLHIYGLSLTLSTQWPRQLQVDGEMVTLPFQLQSLLLVHLSGTGLIVHTTWGLSLVFDGDNFVRLRVPAAYAGTLCGLCGNYNKNSSDDLTAVDGKPEGWKVGGAPDCDQCQLRPCPKPCTPEQQKHFDGPNACGIITAPKGPLAPCHSLVPPTLFFEACLLDACQVQGHPGGLCPAIATYVIACQDAKAQLGEWRKPDFCPLQCPAHSHYQLCGDSCPVSCPSLSAPKGCETICREGCVCDSGFVLSGDTCVPVSQCGCLHNGRYYVLGDTFYPGPECERLCECGPGGQVTCRIEICGIHEECRIEDGIRSCHPKSSKLMLVLHGIHYTTPDGLVYDLYGSCSYILAQLCFLKPGEEEFSIVLEKDLAGEPQRVVVTVADQVVVLAKGPQVTVDSEVVALPIVAGSTYITAEGRNIFLQTKRGLKLLFDGDDHILMSIPSAFRGRICGLCGNFNGNQSDDFVLPNGAVAPNVDAFGAAWRVPGSSLGCGEGCGPQGCPMCLAEKREAFEKNDACGKIRDPQGPFATCHKVLSHSEYFHQCVFDLCTHNGDNAYLCRSLAAYTAACQAAGAAVKPWRTDSFCPLQCPAHSHYSVCTYSCQGSCAALSGLTGCTSQCFEGCECDDHFLLSQGVCIPAQDCGCVHNGQYVPVNSSLVSSDCIERCFCSPNNGLTCHEAGCPSGRVCEIQAGVRGCWPAKGLCSLSVGGNLTTFDGALNTISSPGVYELSSRCPGLLKNVPWYRLLADVQPCLDNDKIVSKVHIFFQGGMVTVIPSKGAWVNGLRVDLPATVLTSVSVRKMPDGSMFVHQKAGVQVWLGKDGHLNVMVGEHYAAMLCGACGNFDGDRSNDVHKYQKKISMETWRAQDFSPCPN", "length": 2581 }, "evidence": [ { "id": "HGNC:13572", "url": "https://alliancegenome.org/gene/HGNC:13572#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y6R7-1", "protein_name": "IgGFc-binding protein", "gene_name": "FCGBP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGALWSWWILWAGATLLWGLTQEASVDLKNTGREEFLTAFLQNYQLAYSKAYPRLLISSLSESPASVSILSQADNTSKKVTVRPGESVMVNISAKAEMIGSKIFQHAVVIHSDYAISVQALNAKPDTAELTLLRPIQALGTEYFVLTPPGTSARNVKEFAVVAGAAGASVSVTLKGSVTFNGKFYPAGDVLRVTLQPYNVAQLQSSVDLSGSKVTASSPVAVLSGHSCAQKHTTCNHVVEQLLPTSAWGTHYVVPTLASQSRYDLAFVVASQATKLTYNHGGITGSRGLQAGDVVEFEVRPSWPLYLSANVGIQVLLFGTGAIRNEVTYDPYLVLIPDVAAYCPAYVVKSVPGCEGVALVVAQTKAISGLTIDGHAVGAKLTWEAVPGSEFSYAEVELGTADMIHTAEATTNLGLLTFGLAKAIGYATAADCGRTVLSPVEPSCEGMQCAAGQRCQVVGGKAGCVAESTAVCRAQGDPHYTTFDGRRYDMMGTCSYTMVELCSEDDTLPAFSVEAKNEHRGSRRVSYVGLVTVRAYSHSVSLTRGEVGFVLVDNQRSRLPVSLSEGRLRVYQSGPRAVVELVFGLVVTYDWDCQLALSLPARFQDQVCGLCGNYNGDPADDFLTPDGALAPDAVEFASSWKLDDGDYLCEDGCQNNCPACTPGQAQHYEGDRLCGMLTKLDGPFAVCHDTLDPRPFLEQCVYDLCVVGGERLSLCRGLSAYAQACLELGISVGDWRSPANCPLSCPANSRYELCGPACPTSCNGAAAPSNCSGRPCVEGCVCLPGFVASGGACVPASSCGCTFQGLQLAPGQEVWADELCQRRCTCNGATHQVTCRDKQSCPAGERCSVQNGLLGCYPDRFGTCQGSGDPHYVSFDGRRFDFMGTCTYLLVGSCGQNAALPAFRVLVENEHRGSQTVSYTRAVRVEARGVKVAVRREYPGQVLVDDVLQYLPFQAADGQVQVFRQGRDAVVRTDFGLTVTYDWNARVTAKVPSSYAEALCGLCGNFNGDPADDLALRGGGQAANALAFGNSWQEETRPGCGATEPGDCPKLDSLVAQQLQSKNECGILADPKGPFRECHSKLDPQGAVRDCVYDRCLLPGQSGPLCDALATYAAACQAAGATVHPWRSEELCPLSCPPHSHYEACSYGCPLSCGDLPVPGGCGSECHEGCVCDEGFALSGESCLPLASCGCVHQGTYHPPGQTFYPGPGCDSLCHCQEGGLVSCESSSCGPHEACQPSGGSLGCVAVGSSTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQQMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPTPCPPGSEDCIPSHKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRTETFCPMECPPNSHYELCADTCSLGCSALSAPPQCQDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHAGKGMVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGSPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFNFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGRRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSEGCIPSEECPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGQVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGAYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVNKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVTQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLAPGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVTLPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAGSLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLREWRRPDFCPFQCPAHSHYELCGDSCPGSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDDRYYPLGQTFYPGPGCDSLCRCREGGEVSCEPSSCGPHETCRPSGGSLGCVAVGSTTCQASGDPHYTTFDGHRFDFMGTCVYVLAQTCGTRPGLHRFAVLQENVAWGNGRVSVTRVITVQVANFTLRLEQRQWKVTVNGVDMKLPVVLANGQIRASQHGSDVVIETDFGLRVAYDLVYYVRVTVPGNYYQLMCGLCGNYNGDPKDDFQKPNGSQAGNANEFGNSWEEVVPDSPCLPPPTCPPGSAGCIPSDKCPPELEKKYQKEEFCGLLSSPTGPLSSCHKLVDPQGPLKDCIFDLCLGGGNLSILCSNIHAYVSACQAAGGHVEPWRNETFCPMECPQNSHYELCADTCSLGCSALSAPLQCPDGCAEGCQCDSGFLYNGQACVPIQQCGCYHNGVYYEPEQTVLIDNCRQQCTCHVGKVVVCQEHSCKPGQVCQPSGGILSCVTKDPCHGVTCRPQETCKEQGGQGVCLPNYEATCWLWGDPHYHSFDGRKFDFQGTCNYVLATTGCPGVSTQGLTPFTVTTKNQNRGNPAVSYVRVVTVAALGTNISIHKDEIGKVRVNGVLTALPVSVADGRISVAQGASKALLVADFGLQVSYDWNWRVDVTLPSSYHGAVCGLCGNMDRNPNNDQVFPNGTLAPSIPIWGGSWRAPGWDPLCWDECRGSCPTCPEDRLEQYEGPGFCGPLSSGTGGPFTTCHAHVPPESFFKGCVLDVCMGGGDRDILCKALASYVAACQAAGVVIEDWRAQVGCEITCPENSHYEVCGPPCPASCPSPAPLTTPAVCEGPCVEGCQCDAGFVLSADRCVPLNNGCGCWANGTYHEAGSEFWADGTCSQWCRCGPGGGSLVCTPASCGLGEVCGLLPSGQHGCQPVSTAECQAWGDPHYVTLDGHRFDFQGTCEYLLSAPCHGPPLGAENFTVTVANEHRGSQAVSYTRSVTLQIYNHSLTLSARWPRKLQVDGVFVALPFQLDSLLHAHLSGADVVVTTTSGLSLAFDGDSFVRLRVPAAYAASLCGLCGNYNQDPADDLKAVGGKPAGWQVGGAQGCGECVSKPCPSPCTPEQQESFGGPDACGVISATDGPLAPCHGLVPPAQYFQGCLLDACQVQGHPGGLCPAVATYVAACQAAGAQLGEWRRPDFCPLQCPAHSHYELCGDSCPVSCPSLSAPEGCESACREGCVCDAGFVLSGDTCVPVGQCGCLHDGRYYPLGEVFYPGPECERRCECGPGGHVTCQEGAACGPHEECRLEDGVQACHATGCGRCLANGGIHYITLDGRVYDLHGSCSYVLAQVCHPKPGDEDFSIVLEKNAAGDLQRLLVTVAGQVVSLAQGQQVTVDGEAVALPVAVGRVRVTAEGRNMVLQTTKGLRLLFDGDAHLLMSIPSPFRGRLCGLCGNFNGNWSDDFVLPNGSAASSVETFGAAWRAPGSSKGCGEGCGPQGCPVCLAEETAPYESNEACGQLRNPQGPFATCQAVLSPSEYFRQCVYDLCAQKGDKAFLCRSLAAYTAACQAAGVAVKPWRTDSFCPLHCPAHSHYSICTRTCQGSCAALSGLTGCTTRCFEGCECDDRFLLSQGVCIPVQDCGCTHNGRYLPVNSSLLTSDCSERCSCSSSSGLTCQAAGCPPGRVCEVKAEARNCWATRGLCVLSVGANLTTFDGARGATTSPGVYELSSRCPGLQNTIPWYRVVAEVQICHGKTEAVGQVHIFFQDGMVTLTPNKGVWVNGLRVDLPAEKLASVSVSRTPDGSLLVRQKAGVQVWLGANGKVAVIVSNDHAGKLCGACGNFDGDQTNDWHDSQEKPAMEKWRAQDFSPCYG", "length": 5405 }, "evidence": [ { "id": "HGNC:13572", "url": "https://alliancegenome.org/gene/HGNC:13572#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-329", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-329#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of BMP signaling pathway", "id": "GO:0030513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030513", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYG1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1493, "end_pos": 1495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1885, "end_pos": 1887, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2381, "end_pos": 2383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2774, "end_pos": 2776, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3270, "end_pos": 3272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3663, "end_pos": 3665, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4159, "end_pos": 4161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4508, "end_pos": 4510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 907, "end_pos": 909, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YYG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYG1" }, { "id": "PS51233", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51233" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFD", "eco_id": "ECO_0000259", "start_pos": 448, "end_pos": 627, "start_aa": "Ala", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1493, "end_pos": 1495 }, { "start_pos": 1885, "end_pos": 1887 }, { "start_pos": 2381, "end_pos": 2383 }, { "start_pos": 2774, "end_pos": 2776 }, { "start_pos": 3270, "end_pos": 3272 }, { "start_pos": 3663, "end_pos": 3665 }, { "start_pos": 4159, "end_pos": 4161 }, { "start_pos": 4508, "end_pos": 4510 }, { "start_pos": 478, "end_pos": 480 }, { "start_pos": 907, "end_pos": 909 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 97 }, { "field": "total_sites", "count": 22 }, { "field": "n_linked_sites", "count": 16 }, { "field": "o_linked_sites", "count": 6 }, { "field": "n_linked_glycan_sites", "count": 11 }, { "field": "o_linked_glycan_sites", "count": 3 }, { "field": "n_linked_glycans", "count": 46 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 22 }, { "field": "exact_n_linked_sites", "count": 16 }, { "field": "exact_n_linked_glycan_sites", "count": 11 }, { "field": "exact_n_linked_glycans", "count": 46 }, { "field": "exact_o_linked_sites", "count": 6 }, { "field": "exact_o_linked_glycan_sites", "count": 3 }, { "field": "exact_o_linked_glycans", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], 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GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017211121.2. 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isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC108183709 PE=4 SV=1 CANONICAL=A0A8M6YYK5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 346, "start_aa": "Thr", "end_pos": 346, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr346", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:108183709", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108183709", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular 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GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211879", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211879" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYL0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYL0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rab33bb", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYL0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080728-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080728-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YYL0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YYL0", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"MDSSLESSSSSNGPPTRCCRTCKIIVIGDAGVGKTCLTHRFCTGQFPTRTEATIGVDFREKLLQIDGEKIKVQLWDTAGQERFRKSMVQHYYRNVHGIVFVFDVTNQSSFCNLPLWMDECRQHSLGLEIPRALVCNKADLMSSNASVLIEQARHLAEVHGMSFYLTSAKGLKGDQVDSIFMALAQRLKSQRRESVNGRVLECRAESLKIQARVITAQETKKKWTCIC", "length": 227, "header": "tr|A0A8M6YYL0-1|A0A8M6YYL0_DANRE Isoform 1 of small monomeric GTPase OS=Danio rerio OX=7955 GN=rab33bb PE=3 SV=1 CANONICAL=A0A8M6YYL0-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YYL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYL0/entry#A0A8M6YYL0-1", "sequence": { "sequence": "MDSSLESSSSSNGPPTRCCRTCKIIVIGDAGVGKTCLTHRFCTGQFPTRTEATIGVDFREKLLQIDGEKIKVQLWDTAGQERFRKSMVQHYYRNVHGIVFVFDVTNQSSFCNLPLWMDECRQHSLGLEIPRALVCNKADLMSSNASVLIEQARHLAEVHGMSFYLTSAKGLKGDQVDSIFMALAQRLKSQRRESVNGRVLECRAESLKIQARVITAQETKKKWTCIC", "length": 227, "header": "tr|A0A8M6YYL0-1|A0A8M6YYL0_DANRE Isoform 1 of small monomeric GTPase OS=Danio rerio OX=7955 GN=rab33bb PE=3 SV=1 CANONICAL=A0A8M6YYL0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YYL7-1", "uniprot_ac": "A0A8M6YYL7", "uniprot_id": "A0A8M6YYL7_DANRE", "mass": { "chemical_mass": 61268.0, "monoisotopic_mass": 61268.0 }, "refseq": { "ac": "XP_017211153", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211153" }, "gene_names": [ { "name": "LOC101883862", "type": "recommended", "evidence": [ { "id": "A0A8M6YYL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYL7" } ] }, { "name": "LOC101883862", "type": "synonym", "evidence": [ { "id": "XP_017211153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211153" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M6YYL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYL7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017211153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211153" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017211153.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211153" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYL7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYL7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101883862", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYL7", "locus": {} } ], "crossref": [ { "id": "A0A8M6YYL7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YYL7", "database": "AlphaFoldDB", "categories": [] }, { "id": "101883862", "url": "https://www.ncbi.nlm.nih.gov/gene/101883862", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:101883862", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101883862", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YYL7", "url": "https://www.orthodb.org/?gene=A0A8M6YYL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47773", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47773", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47773:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47773:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_017211153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211153", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YYL7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YYL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYL7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MALKICLFMFHLFFSGELIGVQYLFQQTGQALQNMNPDCQQTAELIEDLNVDEREEDEGFCDISEDHTIVDPEAALSPSSSTLRSGSSTAVTSSVASLPVSTCPALVPDPPAQPEEPISPVPLEPEEATEDDDEDNDDDDDDDGDEETAVDYQNIPGFQHVDRLAEYLVELRTHKSLSLTNQEANEIIGLWQSLHDQDKKRVVYAARHQKRLLSGRFKTPKKPTHTPGVESTTRCVLGASSAPAQWPDCCRLVETIFIRLCTIHPSPKRKGKGTLSRWSLILQDYRRIRQLVLGNSLVMGGTSMQLVEVNQNTLIQWFNNRQKKQELSVLLQGIQLPQHLPEAQEPLPVAKSLQTEPDQPGEQHQYVLPESTAGQARQRQTSVGRPPLRLKAPVQTQVIFTPPAPGASLQMVPNIYIPATPGYQGMPMFQGVPMFQAVPMVQGIPMAQGIPIMQGVQMAQGIPMVQGMPLRQPPLQPTMSSTSSQPAASPSTSGAIPKRPYRRTVQANTCKKCGQFKTNATGHSQLRGRVYCPQTETLTKEEWLEEMKRTNPK", "length": 553, "header": "tr|A0A8M6YYL7-1|A0A8M6YYL7_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC101883862 PE=4 SV=2 CANONICAL=A0A8M6YYL7-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YYL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYL7/entry#A0A8M6YYL7-1", "sequence": { "sequence": "MALKICLFMFHLFFSGELIGVQYLFQQTGQALQNMNPDCQQTAELIEDLNVDEREEDEGFCDISEDHTIVDPEAALSPSSSTLRSGSSTAVTSSVASLPVSTCPALVPDPPAQPEEPISPVPLEPEEATEDDDEDNDDDDDDDGDEETAVDYQNIPGFQHVDRLAEYLVELRTHKSLSLTNQEANEIIGLWQSLHDQDKKRVVYAARHQKRLLSGRFKTPKKPTHTPGVESTTRCVLGASSAPAQWPDCCRLVETIFIRLCTIHPSPKRKGKGTLSRWSLILQDYRRIRQLVLGNSLVMGGTSMQLVEVNQNTLIQWFNNRQKKQELSVLLQGIQLPQHLPEAQEPLPVAKSLQTEPDQPGEQHQYVLPESTAGQARQRQTSVGRPPLRLKAPVQTQVIFTPPAPGASLQMVPNIYIPATPGYQGMPMFQGVPMFQAVPMVQGIPMAQGIPIMQGVQMAQGIPMVQGMPLRQPPLQPTMSSTSSQPAASPSTSGAIPKRPYRRTVQANTCKKCGQFKTNATGHSQLRGRVYCPQTETLTKEEWLEEMKRTNPK", "length": 553, "header": "tr|A0A8M6YYL7-1|A0A8M6YYL7_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC101883862 PE=4 SV=2 CANONICAL=A0A8M6YYL7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 420, "start_aa": "Thr", "end_pos": 420, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr420", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101883862", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101883862", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 420 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 519, "end_pos": 521 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YYN1-1", "uniprot_ac": "A0A8M6YYN1", "uniprot_id": "A0A8M6YYN1_DANRE", "mass": { "chemical_mass": 53234.0, "monoisotopic_mass": 53234.0 }, "refseq": { "ac": "XP_017211178", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211178" }, "gene_names": [ { "name": "LOC101882666", "type": "recommended", "evidence": [ { "id": "A0A8M6YYN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYN1" } ] }, { "name": "LOC101882666", "type": "synonym", "evidence": [ { "id": "XP_017211178", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211178" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6YYN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYN1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017211178", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211178" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017211178.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211178", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211178" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYN1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101882666", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYN1", "locus": {} } ], "crossref": [ { "id": "A0A8M6YYN1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YYN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "101882666", "url": "https://www.ncbi.nlm.nih.gov/gene/101882666", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101882666", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882666", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YYN1", "url": "https://www.orthodb.org/?gene=A0A8M6YYN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34153", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34153", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34153:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34153:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16064", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16064", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017211178", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211178", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YYN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YYN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JDN0", "url": "https://www.uniprot.org/uniprotkb/A0AC58JDN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JDN0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JDN0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHINNRNVICVFQHYGALGSCSLKKMYLIVEFIHEGSTGPVAKSWYSEGHSWWPPYKEIDRVLKSVRLMEAPQPDKGWTKHQARILHESASFDKISKKWKQACYTSDISESEMPAKRIPKKKIYTSDDEPCDTPHKKKKLNKEKSLPTPRVPPAPKAPTPPRHIRAKGPLVRPQLTSCKTINSFCNSFVRDQQKATEKQQQACFETPSTSQVSAPDVPVRFCQEVEHQDTWDKPQPENQEDTFSVLRPLQDRAPHNTYSVQDPKPSADQRKMLTPVFPISMSHVNEQEDAWGDHPSSYREDTTSELRPSSTQARAKNASGISRWSCISSQCTPVESLAAVVQSLAPRSSGQMEVDTEDDTFPIETIEDLEQLERQLAEKPMMEKMMKRLSIRGGQTLKKTIWRVASKVFGPVAKQLNWCGRGDKRGLKNTNIGTLVIGAAMRNPVLPSPTEAEAEKYLKDFLRLAPGRMAS", "length": 471, "header": "tr|A0A8M6YYN1-1|A0A8M6YYN1_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101882666 PE=4 SV=3 CANONICAL=A0A8M6YYN1-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YYN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYN1/entry#A0A8M6YYN1-1", "sequence": { "sequence": "MHINNRNVICVFQHYGALGSCSLKKMYLIVEFIHEGSTGPVAKSWYSEGHSWWPPYKEIDRVLKSVRLMEAPQPDKGWTKHQARILHESASFDKISKKWKQACYTSDISESEMPAKRIPKKKIYTSDDEPCDTPHKKKKLNKEKSLPTPRVPPAPKAPTPPRHIRAKGPLVRPQLTSCKTINSFCNSFVRDQQKATEKQQQACFETPSTSQVSAPDVPVRFCQEVEHQDTWDKPQPENQEDTFSVLRPLQDRAPHNTYSVQDPKPSADQRKMLTPVFPISMSHVNEQEDAWGDHPSSYREDTTSELRPSSTQARAKNASGISRWSCISSQCTPVESLAAVVQSLAPRSSGQMEVDTEDDTFPIETIEDLEQLERQLAEKPMMEKMMKRLSIRGGQTLKKTIWRVASKVFGPVAKQLNWCGRGDKRGLKNTNIGTLVIGAAMRNPVLPSPTEAEAEKYLKDFLRLAPGRMAS", "length": 471, "header": "tr|A0A8M6YYN1-1|A0A8M6YYN1_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101882666 PE=4 SV=3 CANONICAL=A0A8M6YYN1-1" }, "locus": {} }, { "isoform_ac": "A0AC58JDN0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYN1/entry#A0AC58JDN0-1", "sequence": { "sequence": "MYLIVEFIHEGSTGPVAKSWYSEGHSWWPPYKEIDRVLKSVRLMEAPQPDKGWTKHQARILHESASFDKISKKWKQACYTSDISESEMPAKRIPKKKIYTSDDEPCDTPHKKKKLNKEKSLPTPRVPPAPKAPTPPRHIRAKGPLVRPQLTSCKTINSFCNSFVRDQQKATEKQQQACFETPSTSQVSAPDVPVRFCQEVEHQDTWDKPQPENQEDTFSVLRPLQDRAPHNTYSVQDPKPSADQRKMLTPVFPISMSHVNEQEDAWGDHPSSYREDTTSELRPSSTQARAKNASGISRWSCISSQCTPVESLAAVVQSLAPRSSGQMEVDTEDDTFPIETIEDLEQLERQLAEKPMMEKMMKRLSIRGGQTLKKTIWRVASKVFGPVAKQLNWCGRGDKRGLKNTNIGTLVIGAAMRNPVLPSPTEAEAEKYLKDFLRLAPGRMAS", "length": 446, "header": "tr|A0AC58JDN0-1|A0AC58JDN0_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC101882666 PE=4 SV=1 CANONICAL=A0A8M6YYN1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 159, "start_aa": "Thr", "end_pos": 159, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr159", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101882666", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882666", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YYN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYN1" }, { "id": "PF16064", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16064" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4806", "eco_id": "ECO_0000259", "start_pos": 357, "end_pos": 432, "start_aa": "Glu", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 159 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 317, "end_pos": 319 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": 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This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017211218.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211218" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYP7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYP7#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYP7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYP7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110437783", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYP7", "locus": {} } ], "crossref": [ { "id": "A0A8M6YYP7", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YYP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDLQEQTDLIEEKERSKEEEHHVKIEEKTHLQTDGILKRRDKNSFTCTQCGKILASKSKLKVHMRIHTGEKPFTCTQCGKSFSISSSLNLHMRIHTGEKPFTCTQCGNSFSHLSPFNKHMRIHTGEKPFTCTQCGKSFSLSTSLNLHMRIHAGEKPFTCTRCGKSFNCSSNLSKHMMIHTGEKPFTCTQCEKSFRISSSLNLHMRIHTGEKPFTCTQCGNSFSQSSSLNKHMRIHTGEKPFTCTQCGKSFNRSEHLNLHMRIHTGEKPFTCTECEKSFTCSSHLNRHMRKHTGEKPYACTQCGKIFSQSSCLNLHMVSHNGEKP", "length": 345, "header": "tr|A0A8M6YYP7-1|A0A8M6YYP7_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC110437783 PE=4 SV=2 CANONICAL=A0A8M6YYP7-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YYP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYP7/entry#A0A8M6YYP7-1", "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDLQEQTDLIEEKERSKEEEHHVKIEEKTHLQTDGILKRRDKNSFTCTQCGKILASKSKLKVHMRIHTGEKPFTCTQCGKSFSISSSLNLHMRIHTGEKPFTCTQCGNSFSHLSPFNKHMRIHTGEKPFTCTQCGKSFSLSTSLNLHMRIHAGEKPFTCTRCGKSFNCSSNLSKHMMIHTGEKPFTCTQCEKSFRISSSLNLHMRIHTGEKPFTCTQCGNSFSQSSSLNKHMRIHTGEKPFTCTQCGKSFNRSEHLNLHMRIHTGEKPFTCTECEKSFTCSSHLNRHMRKHTGEKPYACTQCGKIFSQSSCLNLHMVSHNGEKP", "length": 345, "header": "tr|A0A8M6YYP7-1|A0A8M6YYP7_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC110437783 PE=4 SV=2 CANONICAL=A0A8M6YYP7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110437783", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437783", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", 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"biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YYP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYP7" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 93, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 188, "end_pos": 190 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 272, "end_pos": 274 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"uniprot_id": "A0A8M6YYT5_DANRE", "mass": { "chemical_mass": 58468.0, "monoisotopic_mass": 58468.0 }, "refseq": { "ac": "XP_073804543", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073804543" }, "gene_names": [ { "name": "LOC101884860", "type": "recommended", "evidence": [ { "id": "A0A8M6YYT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5" } ] }, { "name": "LOC101884860", "type": "synonym", "evidence": [ { "id": "XP_073804543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073804543" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M6YYT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_073804543", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073804543" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073804543", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073804543" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYT5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101884860", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5", "locus": {} } ], "crossref": [ { "id": "A0A8M6YYT5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YYT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "101884860", "url": "https://www.ncbi.nlm.nih.gov/gene/101884860", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101884860", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884860", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YYT5", "url": "https://www.orthodb.org/?gene=A0A8M6YYT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073804543", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073804543", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YYT5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YYT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASLKEESEGLRITEVFTLKHEDPEEQTGLVVLSEETQELNETEEKDQYGKHQDLMIDEPSLVANNTSCEEAEKTKPFPCHQCEKRFSRKQCLKVHMRIHTGEKLSTCDRCGKIFTTKSDFEIHMRIHTGEKPYSCTECVMSFSGKQKLEMHMRIHTGEKPFACQHCGKRFSRMGSLQVHFRVHTGERPYTCQQCGKSFSQKSSLRAHIIRHTGEKPFPCDQCEKRYVCRDHLNRHKRIHAKDKYFICDQCGSSFKLKENFDQHMKNHAEKSLICDQCGRRCISESSFEKHMRVHTGERPYSCTECGKSFGQKETLTAHMRVHTGEKPFHCQHCGKRFIASSKLKSHMNVHTGNKPYTCRPCGKSFAQLPALKVHMRVHTGERPYTCAQCGKGFAQKKDFHIHMRTHTGERPYTCTQCGKSFICKDTQIRHMRTHFTGKKPFACDECGRRFICKNYLNLHMKIHTEEITCHQSGKRFTERTRKLHMAKQACKSGHNSNPQDLPK", "length": 504, "header": "tr|A0A8M6YYT5-1|A0A8M6YYT5_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC101884860 PE=3 SV=2 CANONICAL=A0A8M6YYT5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YYT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5/entry#A0A8M6YYT5-1", "sequence": { "sequence": "MASLKEESEGLRITEVFTLKHEDPEEQTGLVVLSEETQELNETEEKDQYGKHQDLMIDEPSLVANNTSCEEAEKTKPFPCHQCEKRFSRKQCLKVHMRIHTGEKLSTCDRCGKIFTTKSDFEIHMRIHTGEKPYSCTECVMSFSGKQKLEMHMRIHTGEKPFACQHCGKRFSRMGSLQVHFRVHTGERPYTCQQCGKSFSQKSSLRAHIIRHTGEKPFPCDQCEKRYVCRDHLNRHKRIHAKDKYFICDQCGSSFKLKENFDQHMKNHAEKSLICDQCGRRCISESSFEKHMRVHTGERPYSCTECGKSFGQKETLTAHMRVHTGEKPFHCQHCGKRFIASSKLKSHMNVHTGNKPYTCRPCGKSFAQLPALKVHMRVHTGERPYTCAQCGKGFAQKKDFHIHMRTHTGERPYTCTQCGKSFICKDTQIRHMRTHFTGKKPFACDECGRRFICKNYLNLHMKIHTEEITCHQSGKRFTERTRKLHMAKQACKSGHNSNPQDLPK", "length": 504, "header": "tr|A0A8M6YYT5-1|A0A8M6YYT5_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC101884860 PE=3 SV=2 CANONICAL=A0A8M6YYT5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101884860", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884860", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYT5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYT5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYT5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5" } ], "pmid": "" }, { "name": "regulation of cell differentiation", "id": "GO:0045595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045595", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYT5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYT5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYT5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYT5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYT5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYT5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YYT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYT5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 105, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YYU9-1", "uniprot_ac": "A0A8M6YYU9", "uniprot_id": "A0A8M6YYU9_DANRE", "mass": { "chemical_mass": 48349.0, "monoisotopic_mass": 48349.0 }, "refseq": { "ac": "XP_017212082", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212082" }, "gene_names": [ { "name": "LOC100147899", "type": "recommended", "evidence": [ { "id": "A0A8M6YYU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYU9" } ] }, { "name": "LOC100147899", "type": "synonym", "evidence": [ { "id": "XP_017212082", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212082" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M6YYU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYU9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017212082", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212082" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017212082.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017212082", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212082" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYU9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYU9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100147899", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYU9", "locus": {} } ], "crossref": [ { "id": "A0A8M6YYU9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YYU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100147899", "url": "https://www.ncbi.nlm.nih.gov/gene/100147899", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100147899", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100147899", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR31025", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31025", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31025:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31025:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_017212082", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212082", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YYU9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YYU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYU9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVQDTVIIEEGPDSKRMKLDDEAKKLVQSVLVKKPGGESIINEYNRTKALKDETRRKMVNILAADMTEKNGGSPPRLVKEKYARGIVALFPYLSDPYSKNGFEHYYDGESGTGYLAWRIKTIQRNLAKERRGSFEGQVSYAERGSGGPTVARHSKFTSEIVLSEDECKEAIAFMNHSADEDAIKKKMKLTFDYRRKMVLDPMQSSDLLTIFPRFKDIKGLIEQDFVLMFGEGVSGKLLEKWTTAFKKKVIQQCKRLPATSDLQELLLAAESLRDDTEDDVHIVWDSDLASVLLLHLIPPSAQGRKRPGKVSASQAENHLVVFKKSGTNIEEQLQDISASAQPYLLAVGPQKDSIHQFFIILDQHAIPCKSTSSLGAFDELFKAHYVFGTSYNTMLHNMYTFIQTTVYNIDVGKVKESPRVAEVRARLLN", "length": 429, "header": "tr|A0A8M6YYU9-1|A0A8M6YYU9_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100147899 PE=4 SV=1 CANONICAL=A0A8M6YYU9-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YYU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYU9/entry#A0A8M6YYU9-1", "sequence": { "sequence": "MVQDTVIIEEGPDSKRMKLDDEAKKLVQSVLVKKPGGESIINEYNRTKALKDETRRKMVNILAADMTEKNGGSPPRLVKEKYARGIVALFPYLSDPYSKNGFEHYYDGESGTGYLAWRIKTIQRNLAKERRGSFEGQVSYAERGSGGPTVARHSKFTSEIVLSEDECKEAIAFMNHSADEDAIKKKMKLTFDYRRKMVLDPMQSSDLLTIFPRFKDIKGLIEQDFVLMFGEGVSGKLLEKWTTAFKKKVIQQCKRLPATSDLQELLLAAESLRDDTEDDVHIVWDSDLASVLLLHLIPPSAQGRKRPGKVSASQAENHLVVFKKSGTNIEEQLQDISASAQPYLLAVGPQKDSIHQFFIILDQHAIPCKSTSSLGAFDELFKAHYVFGTSYNTMLHNMYTFIQTTVYNIDVGKVKESPRVAEVRARLLN", "length": 429, "header": "tr|A0A8M6YYU9-1|A0A8M6YYU9_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100147899 PE=4 SV=1 CANONICAL=A0A8M6YYU9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 149, "start_aa": "Thr", "end_pos": 149, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr149", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100147899", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100147899", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 149 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { 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"count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YYX1-1", "uniprot_ac": "A0A8M6YYX1", "uniprot_id": "A0A8M6YYX1_DANRE", "mass": { "chemical_mass": 27495.0, "monoisotopic_mass": 27495.0 }, "refseq": { "ac": "XP_017211437", "name": "microfibril-associated glycoprotein 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Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017211437.2. 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This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017209955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209955" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100536649", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2", "locus": {} } ], "crossref": [ { "id": "A0A8M6YYZ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YYZ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100536649", "url": "https://www.ncbi.nlm.nih.gov/gene/100536649", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100536649", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536649", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YYZ2", "url": "https://www.orthodb.org/?gene=A0A8M6YYZ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384:SF218", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384:SF218", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017209955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209955", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YYZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YYZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"MAFIKVESEDVKIEETFTVKQEDLQEQTDLMVLKEETHGQNETDEKQQFEKPQEIMTDEKPTLTKKTSSHRRLRKSKSGCNFSCKQCRKSFSQKSNLDVHMRVHTREQPFTCEQCGKSFGQIQGFKAHMRIHSGERKFTCQECGKSFRHARNLAAHMRTHTGERKFTCQECGKSFYHAGHFAAHMRIHTGEKPFSCKQCGKSFCQKPNLDVHMRVHTGEKPYTCEQCGKSFSQIQNFKIHMRIHTGERPYTCQQCGKSFYHAGNLAEHMRTHTGEKPFSCKQCRKSFSKKPHLIAHMRVHTREKPYTCEQCEKSLGKNQDLYIHMRIHTGEKPYTCTECGKSFPHKNTLNHHMRIHTGEKPFACAQCGKSFTTKTSLKNHMNVHTGTIVFTCDQCGKSLTRKDTIKKHMKIHSREDRFRCSECGKGFKSKRSLNTHMKIHNAEQNPQH", "length": 448, "header": "tr|A0A8M6YYZ2-1|A0A8M6YYZ2_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC100536649 PE=3 SV=1 CANONICAL=A0A8M6YYZ2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100536649", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536649", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2" } ], "pmid": "" }, { "name": "regulation of immune system process", "id": "GO:0002682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002682", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2" } ], "pmid": "" }, { "name": "regulation of cytokine production", "id": "GO:0001817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001817", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YYZ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 109, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YYZ5-1", "uniprot_ac": "A0A8M6YYZ5", "uniprot_id": "A0A8M6YYZ5_DANRE", "mass": { "chemical_mass": 155493.0, "monoisotopic_mass": 155493.0 }, "refseq": { "ac": "XP_073810625", "name": "membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073810625" }, "gene_names": [ { "name": "magi3b", "type": "recommended", "evidence": [ { "id": "A0A8M6YYZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" } ] }, { "name": "magi3b", "type": "synonym", "evidence": [ { "id": "XP_073810625", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073810625" } ] } ], "protein_names": [ { "name": "Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A8M6YYZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5/entry#names_and_taxonomy" } ] }, { "name": "Membrane-associated guanylate kinase inverted 3", "type": "synonym", "evidence": [ { "id": "A0A8M6YYZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5/entry#names_and_taxonomy" } ] }, { "name": "membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_073810625", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073810625" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073810625", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073810625" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "magi3b", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-301", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-301", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YYZ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YYZ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06730", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06730", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06731", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06731", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06732", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06732", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06733", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06733", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06734", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06734", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06735", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06735", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "564220", "url": "https://www.ncbi.nlm.nih.gov/gene/564220", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008144", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008144", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564220", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564220", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YYZ5", "url": "https://www.orthodb.org/?gene=A0A8M6YYZ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10316", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10316", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10316:SF65", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10316:SF65", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073810625", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073810625", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YYZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6Z7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVW0", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVW0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVZ6", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-301", "url": "https://zfin.org/ZDB-GENE-060503-301", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSKTLKRKKHWSTKVQECAVSWGSVGEFGDVVEILGGAELGEFPFLGQMNLDVLVCHVGRLPYYGDVLLEVNGTPVSGLTNRDTHAVIRHFREPIRIKTVKPGKVLNSDLRHYLSLQFQKGSIDHKLQQVIRDNLYLRTIPCTTRLPRDGEVPGVDYNFISVGDFRILEESGLLLESGTYDGNFYGTPKPPAEPTLVQPDLVDQVLFEEDFGPEVQRKRTTSVSKMDRKDSVVPEEEEDEERPQLPNGIPERTEEWRKAVPSYTQSSGAGGSGTLEIRTWSSLPRDDSLEPLPYNWEMAYTETGMVYFIDHNTKSTTWLDPRLVKKAKPPEKCEDGELPYGWEEIDDPQYGTYYVDHINQRTQFENPVVEAKRKLGLDTAVATQTQQRAAPPPGGAAGTPGFTRDPTQLKGELYHTALRKSQQGFGFTIIGGDRSDEFLQVKNVLSDGPAAQDNKMASGDVIVEINGTLVLGKTHADVVHMFQCIPINQYVDMVLCRGYSLPPDVDADSEDLPPPPPPPTGEIVTAVPLINGQPLLVKGDALHGSSQELHYVTTDASGRPVVAALPASSAANDRPETGMLQPELVSVPIVKGPGGFGFAIADCPLGQKVKMILDEQWCRGLLKGDVIKEINRQNVQTLSHAQVVDILKDLPVGSEVNLLVLRGGQTSPVKSLRPRGGMSASTETLDRCHDMMVPQALTYHSNTLPCSSPKQDASLHYSKPKALTESIVPQYKELDVFIKRDQETGFGFRVLGGEGAEQPVYIGAIIPQGAAEKEGRLRAGDELIGIDGITVKGKSHKQVLDLMTNAARNGQVLLSVRRKVIFRDALEDVGSGALTLVNGSPRLPRIQVPSVKDQESFDITLHRRDNEGFGFVILTSKSKPPPGVCVSVIPHKIGRIIEGSPTDRCGLLNVGDRISAVNSQSIVELSHNDIVQLIKDAGNSVTLTVVPEDEYKGPPSGASSAKQSPAPQHKILKSTQDERYNLDMDEIRDELTWTEYKTPNRQESKQGCIAVELERGPRGFGFSLRGGTEYNMGLYILRLAEDGPALQDGRIHVGDQVVEINGEQTQGISHTRAIELIQAGGNKVLLLLRPQALLPENSSAGDVIVPDPPGSHTSNIPLSSHPTSTSLKKRTGLTDGSLNPSKDSKREKHTKTPNTSSSRVSQQPRRIKSRSAENLLDLGDTEKSKSPSKAKDKAHSHKEKLQQSTRDSQKNRSSRQHSRSVSPQKSRRERQEVEIGETEESHLDQRKSGTDRRKKRESAVRKRNETQERESERKVKSKEDEEVQRKGEAELEGTQKKKKQRNIEMQNGDTLISPDRKSKQTKDKGSLRDQRKENKKEMIRDGSKNKRKGNESESRKDDIDSTDAAPLSTRASLVFDHPGPLSEGLWKDPSYVRILTREEVMRDVFE", "length": 1406, "header": "tr|A0A8M6YYZ5-1|A0A8M6YYZ5_DANRE Isoform 1 of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 OS=Danio rerio OX=7955 GN=magi3b PE=3 SV=2 CANONICAL=A0A8M6YYZ5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YYZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5/entry#A0A8M6YYZ5-1", "sequence": { "sequence": "MSKTLKRKKHWSTKVQECAVSWGSVGEFGDVVEILGGAELGEFPFLGQMNLDVLVCHVGRLPYYGDVLLEVNGTPVSGLTNRDTHAVIRHFREPIRIKTVKPGKVLNSDLRHYLSLQFQKGSIDHKLQQVIRDNLYLRTIPCTTRLPRDGEVPGVDYNFISVGDFRILEESGLLLESGTYDGNFYGTPKPPAEPTLVQPDLVDQVLFEEDFGPEVQRKRTTSVSKMDRKDSVVPEEEEDEERPQLPNGIPERTEEWRKAVPSYTQSSGAGGSGTLEIRTWSSLPRDDSLEPLPYNWEMAYTETGMVYFIDHNTKSTTWLDPRLVKKAKPPEKCEDGELPYGWEEIDDPQYGTYYVDHINQRTQFENPVVEAKRKLGLDTAVATQTQQRAAPPPGGAAGTPGFTRDPTQLKGELYHTALRKSQQGFGFTIIGGDRSDEFLQVKNVLSDGPAAQDNKMASGDVIVEINGTLVLGKTHADVVHMFQCIPINQYVDMVLCRGYSLPPDVDADSEDLPPPPPPPTGEIVTAVPLINGQPLLVKGDALHGSSQELHYVTTDASGRPVVAALPASSAANDRPETGMLQPELVSVPIVKGPGGFGFAIADCPLGQKVKMILDEQWCRGLLKGDVIKEINRQNVQTLSHAQVVDILKDLPVGSEVNLLVLRGGQTSPVKSLRPRGGMSASTETLDRCHDMMVPQALTYHSNTLPCSSPKQDASLHYSKPKALTESIVPQYKELDVFIKRDQETGFGFRVLGGEGAEQPVYIGAIIPQGAAEKEGRLRAGDELIGIDGITVKGKSHKQVLDLMTNAARNGQVLLSVRRKVIFRDALEDVGSGALTLVNGSPRLPRIQVPSVKDQESFDITLHRRDNEGFGFVILTSKSKPPPGVCVSVIPHKIGRIIEGSPTDRCGLLNVGDRISAVNSQSIVELSHNDIVQLIKDAGNSVTLTVVPEDEYKGPPSGASSAKQSPAPQHKILKSTQDERYNLDMDEIRDELTWTEYKTPNRQESKQGCIAVELERGPRGFGFSLRGGTEYNMGLYILRLAEDGPALQDGRIHVGDQVVEINGEQTQGISHTRAIELIQAGGNKVLLLLRPQALLPENSSAGDVIVPDPPGSHTSNIPLSSHPTSTSLKKRTGLTDGSLNPSKDSKREKHTKTPNTSSSRVSQQPRRIKSRSAENLLDLGDTEKSKSPSKAKDKAHSHKEKLQQSTRDSQKNRSSRQHSRSVSPQKSRRERQEVEIGETEESHLDQRKSGTDRRKKRESAVRKRNETQERESERKVKSKEDEEVQRKGEAELEGTQKKKKQRNIEMQNGDTLISPDRKSKQTKDKGSLRDQRKENKKEMIRDGSKNKRKGNESESRKDDIDSTDAAPLSTRASLVFDHPGPLSEGLWKDPSYVRILTREEVMRDVFE", "length": 1406, "header": "tr|A0A8M6YYZ5-1|A0A8M6YYZ5_DANRE Isoform 1 of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 OS=Danio rerio OX=7955 GN=magi3b PE=3 SV=2 CANONICAL=A0A8M6YYZ5-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z6Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5/entry#A0A8M6Z6Z7-1", "sequence": { "sequence": "MSKTLKRKKHWSTKVQECAVSWGSVGEFGDVVEILGGAELGEFPFLGQMNLDVLVCHVGRLPYYGDVLLEVNGTPVSGLTNRDTHAVIRHFREPIRIKTVKPGKVLNSDLRHYLSLQFQKGSIDHKLQQVIRDNLYLRTIPCTTRLPRDGEVPGVDYNFISVGDFRILEESGLLLESGTYDGNFYGTPKPPAEPTLVQPDLVDQVLFEEDFGPEVQRKRTTSVSKMDRKDSVVPEEEEDEERPQLPNGIPERTEEWRKAVPSYTQSSGAGGSGTLEIRTWSSLPRDDSLEPLPYNWEMAYTETGMVYFIDHNTKSTTWLDPRLVKKAKPPEKCEDGELPYGWEEIDDPQYGTYYVDHINQRTQFENPVVEAKRKLGLDTAVATQTQQRAAPPPGGAAGTPGFTRDPTQLKGELYHTALRKSQQGFGFTIIGGDRSDEFLQVKNVLSDGPAAQDNKMASGDVIVEINGTLVLGKTHADVVHMFQCIPINQYVDMVLCRGYSLPPDVDADSEDLPPPPPPPTGEIVTAVPLINGQPLLVKGDALHGSSQELHYVTTDASGRPVVAALPASSAANDRPETGMLQPELVSVPIVKGPGGFGFAIADCPLGQKVKMILDEQWCRGLLKGDVIKEINRQNVQTLSHAQVVDILKDLPVGSEVNLLVLRGGQTSPVKSLRPRGGMSASTETLDRCHDMMVPQALTYHSNTLPCSSPKQDASLHYSKPKALTESIVPQYKELDVFIKRDQETGFGFRVLGGEGAEQPVYIGAIIPQGAAEKEGRLRAGDELIGIDGITVKGKSHKQVLDLMTNAARNGQVLLSVRRKVIFRDALEDVGSGALTLVNGSPRLPRIQVPSVKDQESFDITLHRRDNEGFGFVILTSKSKPPPGVIPHKIGRIIEGSPTDRCGLLNVGDRISAVNSQSIVELSHNDIVQLIKDAGNSVTLTVVPEDEYKGPPSGASSAKQSPAPQHKILKSTQDERYNLDMDEIRDELTWTEYKTPNRQESKQGCIAVELERGPRGFGFSLRGGTEYNMGLYILRLAEDGPALQDGRIHVGDQVVEINGEQTQGISHTRAIELIQAGGNKVLLLLRPQALLPENSSAGDVIVPDPPGSHTSNIPLSSHPTSTSLKKRTGLTDGSLNPSKDSKREKHTKTPNTSSSRVSQQPRRIKSRSAENLLDLGDTEKSKSPSKAKDKAHSHKEKLQQSTRDSQKNRSSRQHSRSVSPQKSRRERQEVEIGETEESHLDQRKSGTDRRKKRESAVRKRNETQERESERKVKSKEDEEVQRKGEAELEGTQKKKKQRNIEMQNGDTLISPDRKSKQTKDKGSLRDQRKENKKEMIRDGSKNKRKGNESESRKDDIDSTDAAPLSTRASLVFDHPGPLSEGLWKDPSYVRILTREEVMRDVFE", "length": 1402, "header": "tr|A0A8M6Z6Z7-1|A0A8M6Z6Z7_DANRE Computationally mapped isoform of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 OS=Danio rerio OX=7955 GN=magi3b PE=3 SV=1 CANONICAL=A0A8M6YYZ5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5/entry#A0AC58JVW0-1", "sequence": { "sequence": "MSKTLKRKKHWSTKVQECAVSWGSVGEFGDVVEILGGAELGEFPFLGQMNLDVLVCHVGRLPYYGDVLLEVNGTPVSGLTNRDTHAVIRHFREPIRIKTVKPGKVLNSDLRHYLSLQFQKGSIDHKLQQVIRDNLYLRTIPCTTRLPRDGEVPGVDYNFISVGDFRILEESGLLLESGTYDGNFYGTPKPPAEPTLVQPDLVDQVLFEEDFGPEVQRKRTTSVSKMDRKDSVVPEEEEDEERPQLPNGIPERTEEWRKAVPSYTQSSGAGGSGTLEIRTWSSLPRDDSLEPLPYNWEMAYTETGMVYFIDHNTKSTTWLDPRLVKKAKPPEKCEDGELPYGWEEIDDPQYGTYYVDHINQRTQFENPVVEAKRKLGLDTAVATQTQQRAAPPPGGAAGTPGFTRDPTQLKGELYHTALRKSQQGFGFTIIGGDRSDEFLQVKNVLSDGPAAQDNKMASGDVIVEINGTLVLGKTHADVVHMFQCIPINQYVDMVLCRGYSLPPDVDADSEDLPPPPPPPTGEIVTAVPLINGQPLLVKGDALHGSSQELHYVTTDASGRPVVAALPASSAANDRPETGMLQPELVSVPIVKGPGGFGFAIADCPLGQKVKMILDEQWCRGLLKGDVIKEINRQNVQTLSHAQVVDILKDLPVGSEVNLLVLRGGQTSPVKSLRPRGGMSASTETLDRCHDMMVPQALTYHSNTLPCSSPKQDASLHYSKPKALTESIVPQYKELDVFIKRDQETGFGFRVLGGEGAEQPVYIGAIIPQGAAEKEGRLRAGDELIGIDGITVKGKSHKQVLDLMTNAARNGQVLLSVRRKVIFRDALEDVGSGALTLVNGSPRLPRIQVPSVKDQESFDITLHRRDNEGFGFVILTSKSKPPPGVIPHKIGRIIEGSPTDRCGLLNVGDRISAVNSQSIVELSHNDIVQLIKDAGNSVTLTVVPEDEYKGPPSGASSAKQSPAPQHKILKSTQDERYNLDMDEIRDELTWTEYKTPNRQESKQGCIAVELERGPRGFGFSLRGGTEYNMGLYILRLAEDGPALQDGRIHVGDQVVEINGEQTQGISHTRAIELIQAGGNKVLLLLRPQALLPENSCVSSSTVCYCPQEHHH", "length": 1110, "header": "tr|A0AC58JVW0-1|A0AC58JVW0_DANRE Computationally mapped isoform of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 OS=Danio rerio OX=7955 GN=magi3b PE=3 SV=1 CANONICAL=A0A8M6YYZ5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5/entry#A0AC58JVZ6-1", "sequence": { "sequence": "MSKTLKRKKHWSTKVQECAVSWGSVGEFGDVVEILGGAELGEFPFLGQMNLDVLVCHVGRLPYYGDVLLEVNGTPVSGLTNRDTHAVIRHFREPIRIKTVKPGKVLNSDLRHYLSLQFQKGSIDHKLQQVIRDNLYLRTIPCTTRLPRDGEVPGVDYNFISVGDFRILEESGLLLESGTYDGNFYGTPKPPAEPTLVQPDLVDQVLFEEDFGPEVQRKRTTSVSKMDRKDSVVPEEEEDEERPQLPNGIPERTEEWRKAVPSYTQSSGAGGSGTLEIRTWSSLPRDDSLEPLPYNWEMAYTETGMVYFIDHNTKSTTWLDPRLVKKAKPPEKCEDGELPYGWEEIDDPQYGTYYVDHINQRTQFENPVVEAKRKLGLDTAVATQTQQRAAPPPGGAAGTPGFTRDPTQLKGELYHTALRKSQQGFGFTIIGGDRSDEFLQVKNVLSDGPAAQDNKMASGDVIVEINGTLVLGKTHADVVHMFQCIPINQYVDMVLCRGYSLPPDVDADSEDLPPPPPPPTGEIVTAVPLINGQPLLVKGDALHGSSQELHYVTTDASGRPVVAALPASSAANDRPETGMLQPELVSVPIVKGPGGFGFAIADCPLGQKVKMILDEQWCRGLLKGDVIKEINRQNVQTLSHAQVVDILKDLPVGSEVNLLVLRGGQTSPVKSLRPRGGMSASTETLDRCHDMMVPQALTYHSNTLPCSSPKQDASLHYSKPKALTESIVPQYKELDVFIKRDQETGFGFRVLGGEGAEQPVYIGAIIPQGAAEKEGRLRAGDELIGIDGITVKGKSHKQVLDLMTNAARNGQVLLSVRRKVIFRDALEDVGSGALTLVNGSPRLPRIQVPSVKDQESFDITLHRRDNEGFGFVILTSKSKPPPGVCVSVIPHKIGRIIEGSPTDRCGLLNVGDRISAVNSQSIVELSHNDIVQLIKDAGNSVTLTVVPEDEYKGPPSGASSAKQSPAPQHKILKSTQDERYNLDMDEIRDELTWTEYKTPNRQESKQGCIAVELERGPRGFGFSLRGGTEYNMGLYILRLAEDGPALQDGRIHVGDQVVEINGEQTQGISHTRAIELIQAGGNKVLLLLRPQALLPENSCVSSSTVCYCPQEHHH", "length": 1114, "header": "tr|A0AC58JVZ6-1|A0AC58JVZ6_DANRE Computationally mapped isoform of Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 3 OS=Danio rerio OX=7955 GN=magi3b PE=3 SV=1 CANONICAL=A0A8M6YYZ5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:564220", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564220", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" } ], "pmid": "" }, { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" } ], "pmid": "" }, { "name": "cilium assembly", "id": "GO:0060271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060271", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" } ], "pmid": "" }, { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YYZ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1097, "end_pos": 1099, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1154, "end_pos": 1156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1211, "end_pos": 1213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1264, "end_pos": 1266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1350, "end_pos": 1352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YYZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" }, { "id": "PS50052", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50052" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate kinase-like", "eco_id": "ECO_0000259", "start_pos": 111, "end_pos": 187, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6YYZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 103, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6YYZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYZ5" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 290, "end_pos": 323, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 399 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1097, "end_pos": 1099 }, { "start_pos": 1154, "end_pos": 1156 }, { "start_pos": 1211, "end_pos": 1213 }, { "start_pos": 1264, "end_pos": 1266 }, { "start_pos": 1350, "end_pos": 1352 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 72, "end_pos": 74 }, { "start_pos": 838, "end_pos": 840 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YZ46-1", "uniprot_ac": "A0A8M6YZ46", "uniprot_id": "A0A8M6YZ46_DANRE", "mass": { "chemical_mass": 199207.0, "monoisotopic_mass": 199207.0 }, "refseq": { "ac": "XP_017210090", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210090" }, "gene_names": [ { "name": "LOC100007467", "type": "recommended", "evidence": [ { "id": "A0A8M6YZ46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ46" } ] }, { "name": "LOC100007467", "type": "synonym", "evidence": [ { "id": "XP_017210090", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210090" } ] } ], "protein_names": [ { "name": "GTPase IMAP family member 8", "type": "recommended", "evidence": [ { "id": "A0A8M6YZ46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ46/entry#names_and_taxonomy" } ] }, { "name": "Immune-associated nucleotide-binding protein 9", "type": "synonym", "evidence": [ { "id": "A0A8M6YZ46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ46/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017210090", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210090" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017210090.1. 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"length": 1640, "header": "tr|A0A8M6YZ46-1|A0A8M6YZ46_DANRE Isoform 1 of GTPase IMAP family member 8 OS=Danio rerio OX=7955 GN=LOC100007467 PE=3 SV=1 CANONICAL=A0A8M6YZ46-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100007467", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100007467", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ46", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ46" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ46", "url": 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"A0A8M6YZ46", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ46" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1617, "end_pos": 1619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YZ46", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ46" }, { "id": "PS51720", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51720" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AIG1-type G", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 255, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1617, "end_pos": 1619 }, { "start_pos": 560, "end_pos": 562 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 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{ "name": "Apical junction component 1 homolog", "type": "synonym", "evidence": [ { "id": "A0A8M6YZ78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ78/entry#names_and_taxonomy" } ] }, { "name": "apical junction component 1 homolog", "type": "synonym", "evidence": [ { "id": "XP_009299428", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299428" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009299428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299428" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ78", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ78" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ajm1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ78", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-797", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-797", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "568961", "url": "https://www.ncbi.nlm.nih.gov/gene/568961", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038825", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038825", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:568961", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568961", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YZ78", "url": "https://www.orthodb.org/?gene=A0A8M6YZ78", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21517", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21517", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21517:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21517:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF26649", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26649", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27982", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27982", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009299428", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299428", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YZ78", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YZ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-797", "url": "https://zfin.org/ZDB-GENE-130530-797", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTRTDPPDILVSTVYQDVKVSSLSTHSKACHPSKQCDSPSVSKLENTRKKSKNKKRHCRSFDTESMDKLRYHTIAMEYPYRRAERYAANPEVAWNALGRQQGHGLHRFSSPDIFSYRLTSQPTAAEMPAEIAVTEQKRRTRSRSASRVQTSLTPVSFDASPPVARRGREAQRAHRNSQPRPEVSPRRESSYGATRAHVNEVHPVKLQPQRSDTSRYSPVYVPEGYDEGRPEKPATSPHVRCRVDIKPDESAMQQGGRKAATPQVDIPWQKYPGSGSRSLTVPRHFSTSRTPTPTESYMGEYRQAYQYSQSMPNSYMQPMEIPLQKVVSPREPREHYGRERRAHSSPNVPTKFFYAEDLGKYGSSAPSRTYYQDDRYSIPSQPYSPKVQYVQDPRTHIVHTVPTRPYYTEVDPYHYSGQHVYAKSYAASEPGAYIIQTPPGRTLYGDDPRTYQIQTAPPRIFYMADPYTPQMEHHIPAKAYYTEGRRHARVVQPQSEDWYGSDVSGYSSHYPSSYVSQITPTRARQEPKLTTWYANPCMEPAKTVTDPRSYSRSWDNILDTHVEREQPVPRGKSDENLLCQGAQTSSERPKPVVVNLSSSPRRYAALSLSENSLIDKSPTEAMSSSSKLWFVTPEITITDNDIRQGNLGKPEARSASWDVLDSKSAQNQEAPQRDAKSRSGESTKEKTHSSTSLQQSLEQLDELLADLVIDYKPPARRTSEDLLDQLKKLIDEEEAVSSARKDSTPGSESGMPLDKQPTSIKIDPDTLRDTDGSCDGLRSTEECSPDQSPDEDDTMMCSNNKCRRTETLFNACLYFKSCHSCYTYYCSRNCRREDWDIHKESCLYGRIGSVCRHIIKHCRETTEVHKAFSRIAKVGYLSRGRGVLFLGFPNPGSSTNFLQFGLESLLMSPTYLSLRELESFKDNLGEYCKELQEAGKEYDPNECFLLNVSIAVGDQVPDGPSPRVQAPTVRKFAKVALASYSPEKKVHRKESDMETLILTPPPGMADIDKEGEEGRKAREICFINIQRELRIRGVFLRHEYPNVYQKLCEFVENNRRFTPTTIYPIDKRTGKQFMCMIMAASEPRTLDWVANPHLLDDII", "length": 1099, "header": "tr|A0A8M6YZ78-1|A0A8M6YZ78_DANRE Isoform 1 of Apical junction component 1 homolog OS=Danio rerio OX=7955 GN=ajm1 PE=4 SV=1 CANONICAL=A0A8M6YZ78-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YZ78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ78/entry#A0A8M6YZ78-1", "sequence": { "sequence": "MTRTDPPDILVSTVYQDVKVSSLSTHSKACHPSKQCDSPSVSKLENTRKKSKNKKRHCRSFDTESMDKLRYHTIAMEYPYRRAERYAANPEVAWNALGRQQGHGLHRFSSPDIFSYRLTSQPTAAEMPAEIAVTEQKRRTRSRSASRVQTSLTPVSFDASPPVARRGREAQRAHRNSQPRPEVSPRRESSYGATRAHVNEVHPVKLQPQRSDTSRYSPVYVPEGYDEGRPEKPATSPHVRCRVDIKPDESAMQQGGRKAATPQVDIPWQKYPGSGSRSLTVPRHFSTSRTPTPTESYMGEYRQAYQYSQSMPNSYMQPMEIPLQKVVSPREPREHYGRERRAHSSPNVPTKFFYAEDLGKYGSSAPSRTYYQDDRYSIPSQPYSPKVQYVQDPRTHIVHTVPTRPYYTEVDPYHYSGQHVYAKSYAASEPGAYIIQTPPGRTLYGDDPRTYQIQTAPPRIFYMADPYTPQMEHHIPAKAYYTEGRRHARVVQPQSEDWYGSDVSGYSSHYPSSYVSQITPTRARQEPKLTTWYANPCMEPAKTVTDPRSYSRSWDNILDTHVEREQPVPRGKSDENLLCQGAQTSSERPKPVVVNLSSSPRRYAALSLSENSLIDKSPTEAMSSSSKLWFVTPEITITDNDIRQGNLGKPEARSASWDVLDSKSAQNQEAPQRDAKSRSGESTKEKTHSSTSLQQSLEQLDELLADLVIDYKPPARRTSEDLLDQLKKLIDEEEAVSSARKDSTPGSESGMPLDKQPTSIKIDPDTLRDTDGSCDGLRSTEECSPDQSPDEDDTMMCSNNKCRRTETLFNACLYFKSCHSCYTYYCSRNCRREDWDIHKESCLYGRIGSVCRHIIKHCRETTEVHKAFSRIAKVGYLSRGRGVLFLGFPNPGSSTNFLQFGLESLLMSPTYLSLRELESFKDNLGEYCKELQEAGKEYDPNECFLLNVSIAVGDQVPDGPSPRVQAPTVRKFAKVALASYSPEKKVHRKESDMETLILTPPPGMADIDKEGEEGRKAREICFINIQRELRIRGVFLRHEYPNVYQKLCEFVENNRRFTPTTIYPIDKRTGKQFMCMIMAASEPRTLDWVANPHLLDDII", "length": 1099, "header": "tr|A0A8M6YZ78-1|A0A8M6YZ78_DANRE Isoform 1 of Apical junction component 1 homolog OS=Danio rerio OX=7955 GN=ajm1 PE=4 SV=1 CANONICAL=A0A8M6YZ78-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 294, "start_aa": "Thr", "end_pos": 294, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr294", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:568961", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568961", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AJA9-1", "protein_name": "Apical junction component 1 homolog", "gene_name": "Ajm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRTDPPDLLVSTVYQDIKVVDPGLTSKRQPCERSVARPAAPTPFNKRHCRSFDFLEALDEPTMETHPEPPPPEPAPPRARPRDSEPRRRTRSKSAPRASQGLATAPASPPVLQRRGREAQRAVRVEGSPRREPSYPALRALANELHPIKLQPQRGGPGRIAPLCATPGRCAPPEPPSGPVPHVRCRLDIKPDEAVLQHAARSSRSCAPRETTSWARTAPQFHGLTVPGPRHVALSRTPTPSDLYCTDPRTLYCDGPLPGPRDYLEHRSQPFTTPPGPTQFFYTEEPEGYAGSFTTSPGLPFDGYCSRPYLSEEPPRPSPRRGGSYYAGEVRTFPIQEPPSRSYYGETTRAYGMPFVPRYVPEEPRAHPGARTFYTEDFGRYRERDVLARTYPHPRSSPPWADWGPRPYRTLQVMPPPAPGPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVRDTRGSSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGESLGRNWYVTPEITITDNDLRSVDRPTAKGWELPGGRPRQPVSTVPEGPASSRQRSLEQLDELITDLVIDSRSPAQAPEPAAEGLGRQLRRLLDSRAAGPGGATLLAPSRSPPASAGSTEEPTGSGEAADASPEPSADEDDLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSSPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPSAAPPGAAARPAPRTPGPTVRKFAKVALAAGSPTRPPPARGGEPDMETLILTPPPGTAGLDEEGEAGRRAREVAFIHIQRELRMRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLLDDIM", "length": 974 }, "evidence": [ { "id": "RGD:1560470", "url": "https://alliancegenome.org/gene/RGD:1560470#orthology", "database": "AGR" }, { "id": "HGNC:37284", "url": "https://alliancegenome.org/gene/HGNC:37284#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-797", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-797#orthology", "database": "AGR" }, { "id": "MGI:2685842", "url": "https://alliancegenome.org/gene/MGI:2685842#orthology", "database": "AGR" }, { "id": "FB:FBgn0261802", "url": "https://alliancegenome.org/gene/FB:FBgn0261802#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C9J069-1", "protein_name": "Apical junction component 1 homolog", "gene_name": "AJM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTRTDPPDLLVSTVYQDIKVATPGPASKCSPCERSVARPAEPAPFNKRHCRSFDFLEALDGPAMETLPEPPPPESAVPRARTREAEPRRRARSKSAPRAPPGLTPAPASPPVLPRRGREAQRAARAEASPRREPAYPALRALANELHPIKLQPQRGGPGRVAPLCAAAGRCAPPEPPAGPAPHVRCRLDIKPDDAVLQHATRGSRSCGPTEAAHWARPAPQFHGLTVPGPRHMALSRTPTPSDSYCADPRAFYCDGPLPGPRDYAERRSLPFTTPPGPTQFFYTEEPQGFRGSFAASPGPTFDAYYPRPYPSEELSGPSPRRMGGYYAGEVRTFPIQEPPSRSYYGEAPRAYGLPYGPRYVPEEPRAHSTARPFYTEDFGRYRERDVLARTYPHPRSSPAWADWGPRPYRTLQVVPPSDPDPLLASWHGGTGTSPPRLATDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVREPRGVSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRAGEGLGRNWYVTPEITITDNDLRATERPSARAWELPGGRTRPPPHAAPDGPTSGRQRSLEQLDELITDLVIDSRPTAGQASEPAADCLGPQLRRLLDSRPAGSGAPALAPPRSPPASAGSAEEPAAPGEAADASPEPSADEDDLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSGPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPGTAPPGTPALPAPAPRSHGPTVRKFAKVALAAGSPARPPPARSREPDMETLILTPPPGTAGLDQDGEAGRRAREVAFIHIQRELRLRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLLDDIM", "length": 976 }, "evidence": [ { "id": "RGD:1560470", "url": "https://alliancegenome.org/gene/RGD:1560470#orthology", "database": "AGR" }, { "id": "HGNC:37284", "url": "https://alliancegenome.org/gene/HGNC:37284#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-797", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-797#orthology", "database": "AGR" }, { "id": "MGI:2685842", "url": "https://alliancegenome.org/gene/MGI:2685842#orthology", "database": "AGR" }, { "id": "FB:FBgn0261802", "url": "https://alliancegenome.org/gene/FB:FBgn0261802#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZTF0-1", "protein_name": "Apical junction component 1 homolog", "gene_name": "Ajm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRTDPPDLLVSTVYQDIKVVDPGLTSKRQPCERSVARPAASTPFNKRHCRSFDFLEALDEPTMETHPEPPPPEPAPPRARPRDGEPRRRTRSKSAPRVPQSLTTAPASPPVLQRRGREAQRAVRVEGSPCREPSYPALRALANELHPIKLQPQRGGPGRIAPLCATPGRCAPPESSAGPVPHVRCRLDIKPDEAVLQHAARSSRSGAPRETSSWARTVPQFHGLTVPGPRHVALSRTPTPSDLYCTDPRPLYCDGPLPGPRDYLEHRTQPFTTPPGPTQFFYTEEPEGYAGSFTASPGLPFDGYCSRPYLSEEPPRPSPRRGGSYYAGEVRTFPIQEPPSRSYYGETTRAYGLPFVPRYVPEEPRVHPGARAFYTEDFGRYRERDALARTYPHPRSSPTWADWGPRPYRTLQVMPPPAPGPLLASWHGGTGTSPPRLVTDSRHYSRSWDNILAPGPRREDPLGRGRSYENLLGREVRDTRGSSPEGRRPPVVVNLSTSPRRYAALSLSETSLTEKGRTGECLGRNWYVTPEITITDNDLRSAERPTAKGWELPGGRPRQPVPVVPEGPASSRQRSLEQLDELITDLVIDSRSPAQAPEPTAEGLGRQLRRLLDSRPAGPGGATALAPSRSPPASAGSTEEPTGSGEAAEASPEPSADEDDLMTCSNARCRRTETMFNACLYFKSCHSCYTYYCSRLCRREDWDAHKARCVYGRVGSVCRHVLQFCRDSSPVHRAFSRIARVGFLSRGRGVLFLGFPSPGSADNFLRFGLEGLLLSPTYLSLRELATHAAPLGSYARELAAAGRLYEPAECFLLSVSVAVGPGAAPPGAAARPAPRSPGPTVRKFAKVALAAGSPTRPPPARGGEPDMETLILTPPPGTAGLDEEGEAGRRAREVAFIHIQRELRLRGVFLRHEFPRVYEQLCEFVEANRRFTPTTIYPTDRRTGRPFMCMIMAASEPRALDWVASANLLDDIM", "length": 974 }, "evidence": [ { "id": "RGD:1560470", "url": "https://alliancegenome.org/gene/RGD:1560470#orthology", "database": "AGR" }, { "id": "HGNC:37284", "url": "https://alliancegenome.org/gene/HGNC:37284#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-797", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-797#orthology", "database": "AGR" }, { "id": "MGI:2685842", "url": "https://alliancegenome.org/gene/MGI:2685842#orthology", "database": "AGR" }, { "id": "FB:FBgn0261802", "url": "https://alliancegenome.org/gene/FB:FBgn0261802#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9PDE6-1", "protein_name": "Apical junction molecule ajm1 alpha/beta domain-containing protein", "gene_name": "CG6448", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVTICSLSAALSCNIAYRFPIYEMEHLDLAGYLGHTPQSWNTLGTFQDQDAVYLSSSRQMLEPILEETSEDEERARSSLIVSLDRRSTLWSSTESETGSVLRIETIKADIDAVSERDFVCPPKRPRRSHDLNSGQISEDCVQLRRPMPYDPEYHNSFERFLALEACARDSFGSQGQRSSIGSRRGGTFEDFYSDRDSSHSLSRSSSLVQFESLERQLTLQEQHQSMNSLGNSSPSLTCESGASTRARTRDSSPESRKGSAPTLSLLKRYESSDCSHLHQTYYELNNLNFEYKQQQELLSRSLREAELKSDLESSSSSSSSSDSSGHSLLSSCLVPGDAVATERGKQDGTNSRRIPPNSAENLSEDSGYCEPRTLKREKSKSIPKNFEKLCEEEEELLLLEEGAPHSRDFKDEHDLCQTEIEQTADTAALACSPSSINSSPERASSESESASPLPSPTGSASTSSAASFTWLHNSLPDIREPRGPLSVEINNSKPKTNGSVLATTRQNSGSTRSSSSADSCDGISLLGPTHSLNELQVLERRRRPRHIRPSQRNCHSNSSSEELEELDNLFVACHTPPRIRRSCSWNERARKVVGVASAGYLNASYQNLTLLNYTDNWLPAEILQKNHKRSPAEEMSKQSSNTCGNYEHMICKGNFLLDEISKVYDKNVSILTDKPVLDTKLPAPVECDLNEPIECSKVQHVQLNIKPPPRQKRLTQQPPAAMTFNGLVKTFDQDPTNLRTSYTQSLEQCHLDEQETAKPASYPPSAISQRFLPKRRFQSQTSAAKQRSLVSSTPNLAASDDGQPESEYDIYVSSAHASMHQLPQTTTLPKPLGILLPAGSRHSFGKEVSFCPVVSKYCWQEQSSEEPTEDQFHSSEGEQGPPSDDELMDPTLVHNTRENENIAALFEPEPEQAHRLREPAIAQKFTGFHTNALLSASTHAEKNLSCEESANVKNKANLATPDCRDQRTEAKTTLEPEPALSSTVSLKPCAVANSSCREETPSDAINEPASATARPLSLPILSEPPTNRAHRILYSSQQLRRYEPKASPINKMPPANELSPQAAAVARTDEKHPTSRSLFSRFTHGLRFSLRRKKKQQQQEPSQVKESPKELRQSPEESQPVDFVHIPLKPPRSSQCGRLDDTIVSETSSGHVHSWQQQEQLGKTSTLQKVTGKPPLPKMPPRSGILTHAPQETTGETVNCHRTEALPSVEREHCNQLTGQLVAKVQAQRMRDTGLSSQIVVAEETHTVNRLAGHGDATRPTVVTAVPVSVAPVAEVDKMGLIETNLDTHETVISGKTRSLMDITCNPLSMPHKRYIVKRLNVNSVAYDVDELDAEVKPSPGGMASVRRPHKSMEFLLDKENQKNILPPENELQKSHDHNPGALSEHQLRVQASLQRLNIPDWFRHYNKGPEKAADGENACTSATGGGYRPGNFTRKRAQESGRWQGLNSKTTSLSSLGSQRSDRSPLLMSPSAHSHHGGQSSYSCGSTTIHGPAPVQIGMGATRWSTSHLNSTQMSPGASQRGSFTRGAPINSSFISVASGSGLLRNSYRQPYLGWRSTEKLSQRTPHERLANSLLTQRTAPPSTRAGNETRTLHSVSTEIQSSIKEVTSAIVHFVNDQQQSQHPRSRSTSPNSRCWLESSFVGTRTLDSPQTPVIDNSPPELARKQQQLHPHQVHLDVGLSPVVSAGQLPHRMNGINRIGNGGVPTRNIAPERSLSSASLEDVLASLLGLPTTLLSGQNSNSYSSYTPNAATTACAASRQQLEVQSAAELQRLRRRSEGDAPTQEKHYSKEQSHKSNSHSVEAVDSAQPNNPKESRRASLGDPALAATRSDIGSGQLQLIEGPTTGFGSGQHVRCRNTKCDQSTSPSDAKKLYKSCHNCSHLYCSRECRRAHWEKHRKACLHSRASNICRQVLATCKDDIDSQRHLSLLARKGSLSQGRGVVRVLFRSAEAAEGFIKNGFQCMGEASYVRWPDLMPAEMGLELYSELLKLSTEYKPETKMLIYVAICVVSEAPGMGQAPVRWERQLVSRCAKLKLCKTVLAELEQHQAALLQPVSVVAVPERTEILILTFNPGQHSNRELILSNILDILSRRGVMLSKHYPEVFERLQTYSEGQSDKFNPVTLHPRDTQTGQNFVCIIMAVHTDNELTKLPSAADGGNRVTTIDVGSTSALVQLELGDDQICKTKSRES", "length": 2190 }, "evidence": [ { "id": "RGD:1560470", "url": "https://alliancegenome.org/gene/RGD:1560470#orthology", "database": "AGR" }, { "id": "HGNC:37284", "url": "https://alliancegenome.org/gene/HGNC:37284#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-797", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-797#orthology", "database": "AGR" }, { "id": "MGI:2685842", "url": "https://alliancegenome.org/gene/MGI:2685842#orthology", "database": "AGR" }, { "id": "FB:FBgn0261802", "url": "https://alliancegenome.org/gene/FB:FBgn0261802#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ78", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ78" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ78", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ78" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell junction organization", "id": "GO:0045216", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045216", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ78", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ78" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 947, "end_pos": 949, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YZ78", 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It is characterized by increased serum red blood cell mass and hemoglobin concentration, hypersensitivity of erythroid progenitors to EPO, and low serum levels of EPO." }, "synonyms": [ { "id": "DOID:0060652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060652", "name": "ECYT1", "description": "" }, { "id": "DOID:0060652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060652", "name": "autosomal dominant benign erythrocytosis", "description": "" }, { "id": "DOID:0060652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060652", "name": "primary familial and congenital polycythemia", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "primary familial polycythemia due to EPO receptor mutation", "description": "Primary familial polycythemia is an inherited hematological disorder resulting from mutations in the erythropoietin (EPO) receptor and is characterized by an elevated absolute red blood cell mass caused by uncontrolled red blood cell production in the presence of low EPO levels." }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "EPOR familial polycythemia", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "PFCP", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "congenital erythrocytosis due to erythropoietin receptor mutation", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "congenital polycythemia due to erythropoietin receptor mutation", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "erythrocytosis, familial, 1", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "erythrocytosis, familial, type 1", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "erythrocytosis, somatic", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "familial erythrocytosis", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "familial erythrocytosis type 1", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "familial erythrocytosis, 1", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "familial polycythemia caused by mutation in EPOR", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "primary congenital erythrocytosis", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "primary familial and congenital polycythemia", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "ECYT1", "description": "" }, { "id": "MONDO:0007572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007572", "name": "erythrocytosis autosomal dominant benign", "description": "" }, { "id": "MIM:133100", "resource": "MIM", "url": "https://www.omim.org/entry/133100", "name": "Erythrocytosis, familial, 1", "description": "Erythrocytosis, familial, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060652" } ] }, { "disease_id": "DOID:0080199", "recommended_name": { "id": "DOID:0080199", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080199", "name": "colorectal carcinoma", "description": "A colorectal cancer that arises from the colon or rectum and invades through the muscularis mucosa into the submucosa." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0080199", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080199" } ] }, { "disease_id": "DOID:10763", "recommended_name": { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries." }, "synonyms": [ { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "HTN", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hyperpiesia", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "vascular hypertensive disorder", "description": "" } ], "unlinked_id_list": [ "DOID:13731", "DOID:11130" ], "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ] }, { "disease_id": "DOID:2224", "recommended_name": { "id": "DOID:2224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2224", "name": "essential thrombocythemia", "description": "A myeloproliferative neoplasm that is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and episodes of thrombosis and/or hemorrhage and that results_in the overproduction of platelets." }, "synonyms": [ { "id": "DOID:2224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2224", "name": "Essential thrombocythaemia", "description": "" }, { "id": "DOID:2224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2224", "name": "familial thrombocytosis", "description": "" }, { "id": "DOID:2224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2224", "name": "hemorrhagic thrombocythemia", "description": "" }, { "id": "DOID:2224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2224", "name": "hereditary thrombocythemia", "description": "" }, { "id": "DOID:2224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2224", "name": "primary Thrombocytosis", "description": "" }, { "id": "MONDO:0008554", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008554", "name": "thrombocythemia 1", "description": "" }, { "id": "MONDO:0008554", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008554", "name": "thrombocythemia 1", "description": "" }, { "id": "MONDO:0008554", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008554", "name": "thrombocythemia type 1", "description": "" }, { "id": "MONDO:0008554", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008554", "name": "thrombocythemia, somatic", "description": "" }, { "id": "MONDO:0008554", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008554", "name": "THCYT1", "description": "" }, { "id": "MONDO:0011173", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011173", "name": "thrombocythemia 2", "description": "Familial thrombocytosis in which the cause of the disease is a mutation in the MPL gene." }, { "id": "MONDO:0011173", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011173", "name": "MPL familial thrombocytosis", "description": "" }, { "id": "MONDO:0011173", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011173", "name": "familial thrombocytosis caused by mutation in MPL", "description": "" }, { "id": "MONDO:0011173", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011173", "name": "thrombocythemia 2", "description": "" }, { "id": "MONDO:0011173", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011173", "name": "thrombocythemia 2, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0011173", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011173", "name": "thrombocythemia type 2", "description": "" }, { "id": "MONDO:0011173", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011173", "name": "THCYT2", "description": "" }, { "id": "MONDO:0013794", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013794", "name": "thrombocythemia 3", "description": "Familial thrombocytosis in which the cause of the disease is a mutation in the JAK2 gene." }, { "id": "MONDO:0013794", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013794", "name": "JAK2 familial thrombocytosis", "description": "" }, { "id": "MONDO:0013794", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013794", "name": "familial thrombocytosis caused by mutation in JAK2", "description": "" }, { "id": "MONDO:0013794", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013794", "name": "thrombocythemia 3", "description": "" }, { "id": "MONDO:0013794", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013794", "name": "thrombocythemia 3, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0013794", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013794", "name": "thrombocythemia type 3", "description": "" }, { "id": "MONDO:0013794", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013794", "name": "THCYT3", "description": "" }, { "id": "MIM:187950", "resource": "MIM", "url": "https://www.omim.org/entry/187950", "name": "Thrombocythemia 1", "description": "Thrombocythemia 1" }, { "id": "MIM:601977", "resource": "MIM", "url": "https://www.omim.org/entry/601977", "name": "Thrombocythemia 2", "description": "Thrombocythemia 2" }, { "id": "MIM:614521", "resource": "MIM", "url": "https://www.omim.org/entry/614521", "name": "Thrombocythemia 3", "description": "Thrombocythemia 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "2224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2224" } ] }, { "disease_id": "DOID:4971", "recommended_name": { "id": "DOID:4971", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4971", "name": "myelofibrosis", "description": "A myeloid neoplasm that is located in the bone marrow which results in bone marrow being replaced by fibrous (scar) tissue." }, "synonyms": [ { "id": "DOID:4971", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4971", "name": "Agnogenic myeloid metaplasia", "description": "" }, { "id": "DOID:4971", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4971", "name": "Aleukemic myelosis", "description": "" }, { "id": "DOID:4971", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4971", "name": "Megakaryocytic myelosclerosis", "description": "" }, { "id": "DOID:4971", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4971", "name": "bone Marrow Fibrosis", "description": "" }, { "id": "DOID:4971", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4971", "name": "myelosclerosis", "description": "" }, { "id": "DOID:4971", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4971", "name": "primary myelofibrosis", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "primary myelofibrosis", "description": "Myelofibrosis with myeloid metaplasia is a myeloproliferative disease with annual incidence of approximately 1 case per 100,000 individuals and age at diagnosis around 60 (an increased prevalence is noted in Ashkenazi Jews). Clinical manifestations depend on the type of blood cell affected and may include anemia, pallor, splenomegaly, hypermetabolic state, petechiae, ecchymosis, bleeding, lymphadenopathy, hepatomegaly, portal hypertension." }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "AMM", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "Agnogenic myeloid metaplasia", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "CIMF", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "chronic idiopathic myelofibrosis", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "idiopathic bone marrow fibrosis", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "idiopathic myelofibrosis", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "myelofibrosis with myeloid metaplasia, somatic", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "myelofibrosis, somatic", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "myelosclerosis with myeloid metaplasia", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "osteomyelofibrosis", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "primary myelofibrosis", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "myelofibrosis with myeloid metaplasia", "description": "" }, { "id": "MONDO:0009692", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009692", "name": "myeloid metaplasia", "description": "" }, { "id": "MIM:254450", "resource": "MIM", "url": "https://www.omim.org/entry/254450", "name": "Myelofibrosis with myeloid metaplasia", "description": "Myelofibrosis with myeloid metaplasia" } ], "unlinked_id_list": [], "evidence": [ { "id": "4971", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4971" } ] }, { "disease_id": "DOID:8552", "recommended_name": { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myeloid leukemia", "description": "A myeloid leukemia that is characterized by over production of white blood cells." }, "synonyms": [ { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "CML", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "CML - chronic Myelogenous Leukemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "Myeloid Leukemia, chronic", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic granulocytic leukaemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic granulocytic leukemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myelogenous leukaemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myelogenous leukemia", "description": "" }, { "id": "DOID:8552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8552", "name": "chronic myeloid leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myeloid leukemia", "description": "A chronic myeloproliferative neoplasm characterized by the expression of the BCR-ABL1 fusion gene. It presents with neutrophilic leukocytosis. It can appear at any age, but it mostly affects middle aged and older individuals. Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly. If untreated, it follows a biphasic or triphasic natural course; an initial indolent chronic phase which is followed by an accelerated phase, a blast phase, or both. Allogeneic stem cell transplantation and tyrosine kinase inhibitors delay disease progression and prolong overall survival." }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "BCR-ABL Positive chronic myelogenous leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "BCR-ABL Positive chronic myelogenous leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "CML", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "CML - chronic myelogenous leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "CML - chronic myelogenous leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic granulocytic leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelocytic leukaemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelocytic leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukaemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemia, BCR-ABL1 Positive", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myelogenous leukemias", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "chronic myeloid leukemia", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "hematopoeitic - chronic myelocytic leukaemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "hematopoeitic - chronic myelocytic leukemia (CML)", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "leukimia, chronic myeloid", "description": "" }, { "id": "MONDO:0011996", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011996", "name": "myeloid leukemia, chronic", "description": "" }, { "id": "MIM:608232", "resource": "MIM", "url": "https://www.omim.org/entry/608232", "name": "Leukemia, chronic myeloid, atypical", "description": "Leukemia, chronic myeloid, atypical" } ], "unlinked_id_list": [], "evidence": [ { "id": "8552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8552" } ] }, { "disease_id": "DOID:9256", "recommended_name": { "id": "DOID:9256", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum." }, "synonyms": [ { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma." }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, advanced, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer with chromosomal instability, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectum cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectum neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "CRC", "description": "" }, { "id": "MIM:114500", "resource": "MIM", "url": "https://www.omim.org/entry/114500", "name": "Colorectal cancer", "description": "Colorectal cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ] }, { "disease_id": "DOID:9744", "recommended_name": { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type 1 diabetes mellitus", "description": "A diabetes mellitus that is characterized by destruction of pancreatic beta cells resulting in absent or extremely low insulin production." }, "synonyms": [ { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "IDDM", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9744", "name": "type I diabetes mellitus", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes mellitus", "description": "A chronic condition characterized by minimal or absent production of insulin by the pancreas." }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "IDDM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1D", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "T1DM", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type 1", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "diabetes mellitis type I", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "immune mediated diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "juvenile diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type 1 diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes", "description": "" }, { "id": "MONDO:0005147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005147", "name": "type I diabetes mellitus", "description": "" }, { "id": "MIM:222100", "resource": "MIM", "url": "https://www.omim.org/entry/222100", "name": "Type 1 diabetes mellitus", "description": "Type 1 diabetes mellitus" } ], "unlinked_id_list": [], "evidence": [ { "id": "9744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9744" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ82", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sh2b3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041210-359", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-359", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YZ82", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YZ82", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01231", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01231", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10412", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10412", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101884640", "url": "https://www.ncbi.nlm.nih.gov/gene/101884640", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030523", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030523", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101884640", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884640", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YZ82", "url": "https://www.orthodb.org/?gene=A0A8M6YZ82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10872:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10872:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08916", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08916", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001429707", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429707", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YZ82", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YZ82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JNL1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JNL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JNL1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JNL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041210-359", "url": "https://zfin.org/ZDB-GENE-041210-359", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNGNTVQQTTSTAPFVAPPCGWREFCELHASTTARELAQHYRRFVRERPVQDVVPPDSFSKQFSALFQHHFSCEVAKNAELSLRPPPPPPLLPMTSRLRITSFSGVLDYRETVRPAPLVAILASKPDASGVPREQEQLLRCSPPDTTHRTRNHSQENERSDFRTGSEGYSPTACDFPSRNDVTHISVSRIRESVCRLFKKSPQLGESSSCCPRDELIPSGGPPVSVECTPHSPPVQVPTNRTSQRAALWERWNPWRTVRRRQEFGSVCKEGQLRYLEVDDTISDTAPQWQRCRLQVRRTNEHSASQRYLLELYDPPKDYRMPKISVHCSDIKEIRRCNRLEMPDNMNTFVLKVAGLTGGFIFEADNEQQVSSWTTELRECMSSRSDNVDGEPFPVSDSLSAARRGSSDPGGQSPLGFGLAEQAYNKTHHFLSSYSWFHGPISRVRAAYLVQHAGVSGHGNFLVRQSETRRGDYVLTFNYQGRAKHLRLSLTEWGQCRVQHLRFPSVMDMLSHFRNCPIPLECGAACDVMLANYVRVNPTHTGQSSAFGSPVLVPFSRWSSEPSLAHCSPDSCPHSSSSMAQSCSPPSSLAGLSHRTPSFLPDRHAPLHRSESVGRRNLLRHPNPLPPLLPNRDSDYELEPPDRGRKRAIDNQYMFF", "length": 656, "header": "tr|A0A8M6YZ82-1|A0A8M6YZ82_DANRE Isoform 1 of SH2B adapter protein 3 isoform X1 OS=Danio rerio OX=7955 GN=sh2b3 PE=3 SV=2 CANONICAL=A0A8M6YZ82-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YZ82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82/entry#A0A8M6YZ82-1", "sequence": { "sequence": "MNGNTVQQTTSTAPFVAPPCGWREFCELHASTTARELAQHYRRFVRERPVQDVVPPDSFSKQFSALFQHHFSCEVAKNAELSLRPPPPPPLLPMTSRLRITSFSGVLDYRETVRPAPLVAILASKPDASGVPREQEQLLRCSPPDTTHRTRNHSQENERSDFRTGSEGYSPTACDFPSRNDVTHISVSRIRESVCRLFKKSPQLGESSSCCPRDELIPSGGPPVSVECTPHSPPVQVPTNRTSQRAALWERWNPWRTVRRRQEFGSVCKEGQLRYLEVDDTISDTAPQWQRCRLQVRRTNEHSASQRYLLELYDPPKDYRMPKISVHCSDIKEIRRCNRLEMPDNMNTFVLKVAGLTGGFIFEADNEQQVSSWTTELRECMSSRSDNVDGEPFPVSDSLSAARRGSSDPGGQSPLGFGLAEQAYNKTHHFLSSYSWFHGPISRVRAAYLVQHAGVSGHGNFLVRQSETRRGDYVLTFNYQGRAKHLRLSLTEWGQCRVQHLRFPSVMDMLSHFRNCPIPLECGAACDVMLANYVRVNPTHTGQSSAFGSPVLVPFSRWSSEPSLAHCSPDSCPHSSSSMAQSCSPPSSLAGLSHRTPSFLPDRHAPLHRSESVGRRNLLRHPNPLPPLLPNRDSDYELEPPDRGRKRAIDNQYMFF", "length": 656, "header": "tr|A0A8M6YZ82-1|A0A8M6YZ82_DANRE Isoform 1 of SH2B adapter protein 3 isoform X1 OS=Danio rerio OX=7955 GN=sh2b3 PE=3 SV=2 CANONICAL=A0A8M6YZ82-1" }, "locus": {} }, { "isoform_ac": "A0AC58JNL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82/entry#A0AC58JNL1-1", "sequence": { "sequence": "MNGNTVQQTTSTAPFVAPPCGWREFCELHASTTARELAQHYRRFVRERPVQDVVPPDSFSKQFSALFQHHFSCEVAKNAELSLRPPPPPPLLPMTSRLRITSFSGVLDYRETVRPAPLVAILASKPDASGVPREQEQLLRCSPPDTTHRTRNHSQENERSDFRTGSEGYSPTACDFPSRNDVTHISVSRIRESVCRLFKKSPQLGESSSCCPRDELIPSGGPPVSVECTPHSPPVQVPTNRTSQRAALWERWNPWRTVRRRQEFGSVCKEGQLRYLEVDDTISDTAPQWQRCRLQVRRTNEHSASQRYLLELYDPPKVRQAFEVLNVYFTRPPF", "length": 334, "header": "tr|A0AC58JNL1-1|A0AC58JNL1_DANRE Computationally mapped isoform of SH2B adapter protein 3 isoform X2 OS=Danio rerio OX=7955 GN=sh2b3 PE=4 SV=1 CANONICAL=A0A8M6YZ82-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101884640", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884640", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4LHY5-1", "protein_name": "Lnk, isoform D", "gene_name": "Lnk", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGGNSTGANTSAFSAGGYIGPTSASSHHSLGTSSAAAAAAAGSDLIPAPIGTGNAMGVSSYAYGGTSWEEFCERHARVAASDFAKACITYINGNLPPEEARNIQHRSFAQKFVESFSAHYDTEFFKRRSTLKSGAGSLDFEEEHEVPKLLSKSLLRRLSFKGLRKGKISLLQAFFHKNSDDLDGSGGSGKQSKTKLAKIVVECRKEGTVNNLTPESLDQPTGSQKWEKCRLVLVKAVGGYMLEFYTPHKATKPRSGVFCFLISEARETTALEMPDRLNTFVLKADNNMEYVIEAESAEEMRSWLATIRYCMRTPPTQQPTIESDGVMASAMQTSPTLPSPNPIGGIQNPQYQQQRGSNGNLVGGGAPLTSSLSADSALGQGGATSASELNVINELGTSPTSGPPDIPVRPHRGEQRLSASSNFDGIEGTENDADVADLTAEMSVFPWFHGTLTRSEAARMVLHSDAAGHGYFLVRQSETRRGEFVLTFNFQGRAKHLRLTISEKGQCRVQHLWFPSIQEMLEHFRHNPIPLESGGTSDVTLTEWVHSHSRLNDPTTAANHDSGQLNDLSTNGNGNGNGNGYDNGQGSSTASNAAGGTASGAAGGGHPSPRHCNEVITMNLSVRLKTNEIELPQEPTHVYFPEQVYFHLDPTTLTVHGSPPPAQNFLDQPHLRASNASLQAAAHHQAGSSGNRHPSDGGSNSGGAGGGSGSSGGAECTGRAVDNQYSFT", "length": 728 }, "evidence": [ { "id": "HGNC:29605", "url": "https://alliancegenome.org/gene/HGNC:29605#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-359", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-359#orthology", "database": "AGR" }, { "id": "MGI:893598", "url": "https://alliancegenome.org/gene/MGI:893598#orthology", "database": "AGR" }, { "id": "FB:FBgn0028717", "url": "https://alliancegenome.org/gene/FB:FBgn0028717#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O09039-1", "protein_name": "SH2B adapter protein 3", "gene_name": "Sh2b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNEPTVQPSRTSSAPASPASPRGWSDFCEQHAAAAARELARQYWLFARAHPQPPRADLVSLQFAELFQRHFCREVRESLAGPPGHDYRATAPPRPALPKARSSEDLGPRPACALQHLRRGLRQLFRRRSAGELPGATSDTNDIDTTAASRPGPARKLLPWGLREPPTEALKEVVLRYSLADEAAMDSGARWQRGRLVLRSPGPGHSHFLQLFDPPKSSKPKLQEACSSIREVRPCTRLEMPDNLYTFVLKVQDQTDIIFEVGDEQQLNSWLAELRASTGLGLEHPDTELPLSLAAEPGPARSPRGSTDSLDQGASPGVLLDPACQKTDHFLSCYPWFHGPISRVRAAQLVQLQGPDAHGVFLVRQSESRRGEYVLTFNLQGRAKHLRLVLTERGQCRVQHLHFPSVVDMLRHFQRSPIPLECGAACDVRLSGYVVVLSQAPGSSNTVLFPFSLPHWDSELGHPHLSSVGCPPSHGAEALPGQVTPPEQIFHLVPSPEELANSLRQLELESVSSARDSDYDMDSSSRGHLRAIDNQYTPLSQLCREADV", "length": 548 }, "evidence": [ { "id": "HGNC:29605", "url": "https://alliancegenome.org/gene/HGNC:29605#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-359", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-359#orthology", "database": "AGR" }, { "id": "MGI:893598", "url": "https://alliancegenome.org/gene/MGI:893598#orthology", "database": "AGR" }, { "id": "FB:FBgn0028717", "url": "https://alliancegenome.org/gene/FB:FBgn0028717#orthology", "database": "AGR" }, { "id": "RGD:68411", "url": "https://alliancegenome.org/gene/RGD:68411#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O14492-1", "protein_name": "SH2B adapter protein 2", "gene_name": "SH2B2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGAGPGPAAAAPVPVPVPVPDWRQFCELHAQAAAVDFAHKFCRFLRDNPAYDTPDAGASFSRHFAANFLDVFGEEVRRVLVAGPTTRGAAVSAEAMEPELADTSALKAAPYGHSRSSEDVSTHAATKARVRKGFSLRNMSLCVVDGVRDMWHRRASPEPDAAAAPRTAEPRDKWTRRLRLSRTLAAKVELVDIQREGALRFMVADDAAAGSGGSAQWQKCRLLLRRAVAEERFRLEFFVPPKASRPKVSIPLSAIIEVRTTMPLEMPEKDNTFVLKVENGAEYILETIDSLQKHSWVADIQGCVDPGDSEEDTELSCTRGGCLASRVASCSCELLTDAVDLPRPPETTAVGAVVTAPHSRGRDAVRESLIHVPLETFLQTLESPGGSGSDSNNTGEQGAETDPEAEPELELSDYPWFHGTLSRVKAAQLVLAGGPRNHGLFVIRQSETRPGEYVLTFNFQGKAKHLRLSLNGHGQCHVQHLWFQSVLDMLRHFHTHPIPLESGGSADITLRSYVRAQDPPPEPGPTPPAAPASPACWSDSPGQHYFSSLAAAACPPASPSDAAGASSSSASSSSAASGPAPPRPVEGQLSARSRSNSAERLLEAVAATAAEEPPEAAPGRARAVENQYSFY", "length": 632 }, "evidence": [ { "id": "FB:FBgn0028717", "url": "https://alliancegenome.org/gene/FB:FBgn0028717#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50745-1", "protein_name": "SH2B adapter protein 3", "gene_name": "Sh2b3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRTQGKHRPRVRTCPSLVPFDNPCWPPSHQPLPLQVGAPGHRVTSFLSGRAWPSYIPKGKHGLPGPRYVPDPWSLGVLGHVAPLRVTTTIFLPGASPGVMLDPACQKTDHFLSCYPWFHGPISRVRAAQLVQLQGPDAHGVFLVRQSESRRGEYVLTFNLQGRAKHLRLVLTERGQCRVQHLHFPSVVDMLRHFQRSPIPLECGAACDVRLSGYVVVVSQAPGRKPKVVSRGGVTASTARTKLPSWLRLLHGVIHVISPGSSNTVLFPFSLPHWDSELGHPHLSSAGCPPGHGAEALRGQVTPPEQIFHLVPSPEELANSLRQLELESVSSARDSDYEMDSSSRSHLRAIDNQYTPLSQLCREANL", "length": 368 }, "evidence": [ { "id": "HGNC:29605", "url": "https://alliancegenome.org/gene/HGNC:29605#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-359", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-359#orthology", "database": "AGR" }, { "id": "MGI:893598", "url": "https://alliancegenome.org/gene/MGI:893598#orthology", "database": "AGR" }, { "id": "RGD:68411", "url": "https://alliancegenome.org/gene/RGD:68411#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q62985-1", "protein_name": "SH2B adapter protein 1", "gene_name": "Sh2b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGAPSPEDGVFPSPPALPPPPPPSWQEFCESHARAAALDLARRFRLYLASHPQYAEPGAEAAFSGRFAELFLQHFEAEVARASGSLSPPVLAPLSPGVEIPPSHDLSLESCRVGGPLAVLGPSRSSEDLAGPLPSSVSSSTTSSKPKLKKRFSLRSVGRSVRGSVRGILQWRGAVESPSQAGPLETTSGPPVLGGNSNSNSSGGAGTVGRALANDGTSPGERWTHRFERLRLSRGGGTLRDGAGVIQREELLSFMGAEEAAPDPAGVGRGGGAAGLTSGGGGQPQWQKCRLLLRSEGEGGGGSRLEFFVPPKASRPRLSIPCSTITDVRTATALEMPDRENTFVVKVEGPSEYILETTDALHVKAWVSDIQECLSPGPCPAISPRPMTLPLAPGTSFLTKDNTESLELPCLNHSESLPSQDLLLGPSESNDRLSQGAYGGLSDRPSASFSPSSASIAASHFDSMELLPPELPPRIPIEEGPPAGTVHPLSTPYPPLDTPEAATGSFLFQGEAEGGEGDQPLSGYPWFHGMLSRLKAAQLVLEGGTSSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSQRQQERSTSRDPTQPSEPPPWTDPPHPGAEEASGAPEVAAATAAAAKERQEKEKAGGGGVQEELVPMAELVPMAELEEAIAPGTEAQGGAGSSGDLEVSLMVQLQQLPLGGNGEEGGHPRAINNQYSFV", "length": 756 }, "evidence": [ { "id": "FB:FBgn0028717", "url": "https://alliancegenome.org/gene/FB:FBgn0028717#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91ZM2-1", "protein_name": "SH2B adapter protein 1", "gene_name": "Sh2b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGAPSPEDGVFPSPPALPPPPPPSWQEFCESHARAAALDLARRFRLYLASHPQYAEPGAEAAFSGRFAELFLQHFEAEVARASGSLSPPVLAPLSPGVEIPPSHDLSLESCRVGGPLAVLGPSRSSEDLAGPLPSSVPSSTTSSKPKLKKRFSLRSVGRSVRGSVRGILQWRGAVDSPSQAGPLETTSGPPVLGGNSNSNSSGGAGTVGRALANDGTSPGERWTHRFERLRLSRGGGTLKDGAGMIQREELLSFMGAEEAAPDPAGVGRGGGAAGLTSGGGGQPQWQKCRLLLRSEGEGGGGSRLEFFVPPKASRPRLSIPCSTITDVRTATALEMPDRENTFVVKVEGPSEYILETSDALHVKAWVSDIQECLSPGPCPAISPRPMTLPLAPGTSFFTKDNTDSLELPCLNHSESLPSQDLLLGPSESNDRLSQGAYGGLSDRPSASFSPSSASIAASHFDSMELLPPELPPRIPIEEGPPAGTVHPLSTPYPPLDTPEAATGSFLFQGESEGGEGDQPLSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSQRQQERSTSRDPAQPSEPPPWTDPPHPGAEEASGAPEVAAATAAAAKERQEKEKAGSGGVQEELVPVAELVPMVELEEAIAPGTEAQGGAGSSGDLEVSLMVQLQQLPLGGNGEEGGHPRAINNQYSFV", "length": 756 }, "evidence": [ { "id": "FB:FBgn0028717", "url": "https://alliancegenome.org/gene/FB:FBgn0028717#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JID9-1", "protein_name": "SH2B adapter protein 2", "gene_name": "Sh2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGATPSSAAAPAPVPDWRQFCELHAQVAAVDFAHKFCRFLRDNPTYDTPDAGTSFSRHFAANFLAVFSEEVRRVLGSAADTMEPEPAVTSVTSALKTATYGHSRSSEDVSAHAATKARVRKGFSLRNMSLCVVDGVRDLWHRRSSPEPDGGATPKAAEPASEPRDKWTRRLRLARTLAAKVELVDIQREGALRFMVADDAASGPGGTAQWQKCRLLLRRAVAGERFRLEFFVPPKASRPKVSIPLSAIIEVRTTMPLEMPEKDNTFVLKVENGAEYILETIDSLQKHSWVADIQGCVDPGDSEEDTGLSCARGGCLASRVASCSCELLTDADMPRPPETTTAVGAVVTAPHGRARDTVGESLAHVPLETFLQTLESSGGVSENNNPGDEGAELDTDAEAELELSDYPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKHLRLSLNGHGQCHVQHLWFQSVFDMLRHFHTHPIPLESGGSADITLRSYVRAQGPPPDPGPAPNTAAPVPACWTEPAGQHYFSSLATATCPPASPSNGAGASSSSGSSSSATSLPPRPAEGPLSAHSRSNSTEHLLDAASGATEEPTEATLGRARAVENQYSFY", "length": 621 }, "evidence": [ { "id": "FB:FBgn0028717", "url": "https://alliancegenome.org/gene/FB:FBgn0028717#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRF2-1", "protein_name": "SH2B adapter protein 1", "gene_name": "SH2B1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGAPSPEDGASPSSPPLPPPPPPSWREFCESHARAAALDFARRFRLYLASHPQYAGPGAEAAFSRRFAELFLQHFEAEVARASGSLSPPILAPLSPGAEISPHDLSLESCRVGGPLAVLGPSRSSEDLAGPLPSSVSSSSTTSSKPKLKKRFSLRSVGRSVRGSVRGILQWRGTVDPPSSAGPLETSSGPPVLGGNSNSNSSGGAGTVGRGLVSDGTSPGERWTHRFERLRLSRGGGALKDGAGMVQREELLSFMGAEEAAPDPAGVGRGGGVAGPPSGGGGQPQWQKCRLLLRSEGEGGGGSRLEFFVPPKASRPRLSIPCSSITDVRTTTALEMPDRENTFVVKVEGPSEYIMETVDAQHVKAWVSDIQECLSPGPCPATSPRPMTLPLAPGTSFLTRENTDSLELSCLNHSESLPSQDLLLGPSESNDRLSQGAYGGLSDRPSASISPSSASIAASHFDSMELLPPELPPRIPIEEGPPTGTVHPLSAPYPPLDTPETATGSFLFQGEPEGGEGDQPLSGYPWFHGMLSRLKAAQLVLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEEGQCRVQHLWFQSIFDMLEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQEPTTSHDPPQPPEPPSWTDPPQPGAEEASRAPEVAAAAAAAAKERQEKEKAGGGGVPEELVPVVELVPVVELEEAIAPGSEAQGAGSGGDAGVPPMVQLQQSPLGGDGEEGGHPRAINNQYSFV", "length": 756 }, "evidence": [ { "id": "FB:FBgn0028717", "url": "https://alliancegenome.org/gene/FB:FBgn0028717#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9UQQ2-1", "protein_name": "SH2B adapter protein 3", "gene_name": "SH2B3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNGPALQPSSPSSAPSASPAAAPRGWSEFCELHAVAAARELARQYWLFAREHPQHAPLRAELVSLQFTDLFQRYFCREVRDGRAPGRDYRDTGRGPPAKAEASPEPGPGPAAPGLPKARSSEELAPPRPPGPCSFQHFRRSLRHIFRRRSAGELPAAHTAAAPGTPGEAAETPARPGLAKKFLPWSLAREPPPEALKEAVLRYSLADEASMDSGARWQRGRLALRRAPGPDGPDRVLELFDPPKSSRPKLQAACSSIQEVRWCTRLEMPDNLYTFVLKVKDRTDIIFEVGDEQQLNSWMAELSECTGRGLESTEAEMHIPSALEPSTSSSPRGSTDSLNQGASPGGLLDPACQKTDHFLSCYPWFHGPISRVKAAQLVQLQGPDAHGVFLVRQSETRRGEYVLTFNFQGIAKHLRLSLTERGQCRVQHLHFPSVVDMLHHFQRSPIPLECGAACDVRLSSYVVVVSQPPGSCNTVLFPFSLPHWDSESLPHWGSELGLPHLSSSGCPRGLSPEGLPGRSSPPEQIFHLVPSPEELANSLQHLEHEPVNRARDSDYEMDSSSRSHLRAIDNQYTPL", "length": 575 }, "evidence": [ { "id": "HGNC:29605", "url": "https://alliancegenome.org/gene/HGNC:29605#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-359", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-359#orthology", "database": "AGR" }, { "id": "MGI:893598", "url": "https://alliancegenome.org/gene/MGI:893598#orthology", "database": "AGR" }, { "id": "FB:FBgn0028717", "url": "https://alliancegenome.org/gene/FB:FBgn0028717#orthology", "database": "AGR" }, { "id": "RGD:68411", "url": "https://alliancegenome.org/gene/RGD:68411#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z200-1", "protein_name": "SH2B adapter protein 2", "gene_name": "Sh2b2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGATPGSAAAPAPVPDWRQFCELHAQVAAVDFAHKFCRFLRDNPTYDTPDAGTSFSRHFAANFLAVFSEEVRRVLGTAADTMEPEPAVTSVTSALKTATYGHSRSSEDVSAHVATKARVRKGFSLRNMSLCVVDGVRDLWHRRASPEPEGGATPKTTEPVSEPRDKWTRRLRLARTLAAKVELVDIQREGALRFMVADDAASGPGGTAQWQKCRLLLRRAVAGERFRLEFFVPPKASRPKVSIPLSAIIEVRTTMPLEMPEKDNTFVLKVENGAEYILETIDSLQKHSWVADIQGCVDPGDSEEDTGLSCARGGCLASRVTSCSCELLTEADMPRPPETMTAVGAVVTAPHGRARDTVGESLAHVPLETFLQTLESSGGVSESNNTGDEGAELDPDAEAELELSDYPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKHLRLSLNGHGQCHVQHLWFQSVFDMLRHFHTHPIPLESGGSADITLRSYVRAQGPPPDPGPAPNTAAPVPACWTEPAGQHYFSSLATATCPPTSPSNGAGASSSSGSSSSATSVPPRPAEGPLSARSRSNSTEHLLEAASGATEEPADATLGRARAVENQYSFY", "length": 621 }, "evidence": [ { "id": "FB:FBgn0028717", "url": "https://alliancegenome.org/gene/FB:FBgn0028717#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ82", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ82", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82" } ], "pmid": "" }, { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ82", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82" } ], "pmid": "" }, { "name": "negative regulation of response to cytokine stimulus", "id": "GO:0060761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060761", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ82", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82" } ], "pmid": "" }, { "name": "thrombopoietin-mediated signaling pathway", "id": "GO:0038163", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038163", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ82", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane receptor protein tyrosine kinase adaptor activity", "id": "GO:0005068", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005068", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ82", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ82" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 436, "end_pos": 534, "start_aa": "Trp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 240, "end_pos": 242 }, { "start_pos": 425, "end_pos": 427 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YZ89-1", "uniprot_ac": "A0A8M6YZ89", "uniprot_id": "A0A8M6YZ89_DANRE", "mass": { "chemical_mass": 59632.0, "monoisotopic_mass": 59632.0 }, "refseq": { "ac": "NP_001410400", "name": "nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410400" }, "gene_names": [ { "name": "nacc1a", "type": "recommended", "evidence": [ { "id": "A0A8M6YZ89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" } ] }, { "name": "id:ibd2897", "type": "synonym", "evidence": [ { "id": "NP_001410400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410400" }, { "id": "A0A8M6YZ89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" } ] }, { "name": "nacc1a", "type": "synonym", "evidence": [ { "id": "NP_001410400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410400" } ] } ], "protein_names": [ { "name": "Nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a", "type": "synonym", "evidence": [ { "id": "A0A8M6YZ89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89/entry#names_and_taxonomy" } ] }, { "name": "nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a", "type": "synonym", "evidence": [ { "id": "NP_001410400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410400" } ] }, { "name": "nucleus accumbens-associated protein 1-like", "type": "synonym", "evidence": [ { "id": "NP_001410400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410400" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01022353.1, SRR26395014.565289.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505390 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On Jul 25, 2023 this sequence version replaced XP_017210279.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001410400", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410400" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ89", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nacc1a", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-010319-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-010319-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd18290", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18290", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103910274", "url": "https://www.ncbi.nlm.nih.gov/gene/103910274", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:103910274", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910274", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YZ89", "url": "https://www.orthodb.org/?gene=A0A8M6YZ89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001410400", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410400", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YZ89", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YZ89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q501", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q501", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q501-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q501-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-010319-3", "url": "https://zfin.org/ZDB-GENE-010319-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAQTLQMAIPNFGNNVLECLNEQRLQGLYCDVSVVVKGHTFKAHRAVLAASSSYFRDLFNSSAGSKTPTVVELPPAVQPQSFQQILAFCYTGRLSMNVGDQFLLMYTAGFLQIQQIMEKGTEFFLKVSSPSCDSQGLHTEETPPSEPQSPVTQTAAGAAANGGAGVVATAASRPASCLTPLPLVSRVKTEQPETSPYSVVCTPVAKRLWEGSNREGSGGLGAAGGGGMRKAARFSQEMARGSAIQQQGSMGGLGMGLGMGTGGHGAGSGSTNGNGTSSATPEGTSPGTLSAYASDSPISYHDDEEEEEAVDDGTEEQYRQICNMYTMYSMLNVGATAGERVEALPDHSETRPRMRGRQDLASLPAELIAQIGNRCHPKLYEEGDPAEKLELVSGTSVYISRAQLMNCHVSAGTRHKVLLRRLLAAFFDRSTLANSCGTGIRSSTNDPSRKPLDSRVLHAVKFYCQNFATSFKESEMNAIAADMCTNARRVVRKSWIPKLKLLMAEGDAYASFLPDSNKMEADGLSGEPTFETASLEGGASVETGGSSGESLQGVGGDNGTLFQ", "length": 563, "header": "tr|A0A8M6YZ89-1|A0A8M6YZ89_DANRE Isoform 1 of Nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a OS=Danio rerio OX=7955 GN=nacc1a PE=4 SV=1 CANONICAL=A0A8M6YZ89-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YZ89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89/entry#A0A8M6YZ89-1", "sequence": { "sequence": "MAQTLQMAIPNFGNNVLECLNEQRLQGLYCDVSVVVKGHTFKAHRAVLAASSSYFRDLFNSSAGSKTPTVVELPPAVQPQSFQQILAFCYTGRLSMNVGDQFLLMYTAGFLQIQQIMEKGTEFFLKVSSPSCDSQGLHTEETPPSEPQSPVTQTAAGAAANGGAGVVATAASRPASCLTPLPLVSRVKTEQPETSPYSVVCTPVAKRLWEGSNREGSGGLGAAGGGGMRKAARFSQEMARGSAIQQQGSMGGLGMGLGMGTGGHGAGSGSTNGNGTSSATPEGTSPGTLSAYASDSPISYHDDEEEEEAVDDGTEEQYRQICNMYTMYSMLNVGATAGERVEALPDHSETRPRMRGRQDLASLPAELIAQIGNRCHPKLYEEGDPAEKLELVSGTSVYISRAQLMNCHVSAGTRHKVLLRRLLAAFFDRSTLANSCGTGIRSSTNDPSRKPLDSRVLHAVKFYCQNFATSFKESEMNAIAADMCTNARRVVRKSWIPKLKLLMAEGDAYASFLPDSNKMEADGLSGEPTFETASLEGGASVETGGSSGESLQGVGGDNGTLFQ", "length": 563, "header": "tr|A0A8M6YZ89-1|A0A8M6YZ89_DANRE Isoform 1 of Nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a OS=Danio rerio OX=7955 GN=nacc1a PE=4 SV=1 CANONICAL=A0A8M6YZ89-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q501-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89/entry#A0A8M9Q501-1", "sequence": { "sequence": "MAQTLQMAIPNFGNNVLECLNEQRLQGLYCDVSVVVKGHTFKAHRAVLAASSSYFRDLFNSSAGSKTPTVVELPPAVQPQSFQQILAFCYTGRLSMNVGDQFLLMYTAGFLQIQQIMEKGTEFFLKVSSPSCDSQGLHTEETPPSEPQSPVTQTAAGAAANGGAGVVATAASRPASCLTPLPLVSRVKTEQPETSPYSVVCTPVAKRLWEGSNREGSGGLGAAGGGGMRKAARFSQEMARGSAIQQQGSMGGLGMGLGMGTGGHGAGSGSTNGNGTSSATPEGTSPGTLSAYASDSPISYHDDEEEEEAVDDGTEEQYRQICNMYTMYSMLNVGATGERVEALPDHSETRPRMRGRQDLASLPAELIAQIGNRCHPKLYEEGDPAEKLELVSGTSVYISRAQLMNCHVSAGTRHKVLLRRLLAAFFDRSTLANSCGTGIRSSTNDPSRKPLDSRVLHAVKFYCQNFATSFKESEMNAIAADMCTNARRVVRKSWIPKLKLLMAEGDAYASFLPDSNKMEADGLSGEPTFETASLEGGASVETGGSSGESLQGVGGDNGTLFQ", "length": 562, "header": "tr|A0A8M9Q501-1|A0A8M6YZ89_DANRE Computationally mapped isoform of Nucleus accumbens associated 1, BEN and BTB (POZ) domain containing a OS=Danio rerio OX=7955 GN=nacc1a PE=4 SV=1 CANONICAL=A0A8M6YZ89-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A gene expression screen in zebrafish embryogenesis.", "journal": "Genome Res.", "date": "2001", "authors": "Kudoh T, Tsang M, Hukriede N A, Chen X, Dedekian M, Clarke C J, Kiang A, Schultz S, Epstein J A, Toyama R, Dawid I B", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ89", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" } ], "reference": [ { "type": "PubMed", "id": "11731487", "url": "https://glygen.org/publication/PubMed/11731487" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ89", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:103910274", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910274", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AC58GTE3-1", "protein_name": "Nucleus accumbens-associated protein 1 isoform X1", "gene_name": "nacc1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAARREKESDSSIETLSSRLQARGLCSAGLYDMAQMLQMAIPNFGNNILECLNEQRLQGLYCDVSVVVKGHTFKAHRAVLAASSSYFRDLFNSGSKSSVVELPPAVQPQSFQQILSFCYTGRLSMNLGDQFLLMYTAGFLQIQQIMEKGTEFFLKVSSPSCDSQGLHTEDAPPSEPQSPVTQTGTGSIGMGGSTAARPASCQTPLPLVSRVKTEQLPQAPQPLQEASSYSVVCTPVAKRLWEGGNREGGGGSGGSGGGGVRKAARYSQEVVRSVGGAQPQSIALLGGSGTTNSNSNNNNNNNSSSTPEGTSPGTPSMYTSDSPISYHDDDEEEEIPDETTEEQYRQICNMYTMYSMLNVGATANERVESLPDHLTVESRGRGVRVRQDLASLPTELIAQIGNRCHPKLYEEGDPAEKLELVTGTSVFISRAQLMNCHVSAGTRHKVLLRRLLAAFFDRSTLANSCGTGIRSSTNDPNRKPLDSRVLHAVKFYCQNFAPSFKESEMNAIAADMCTNARRVVRKSWIPKLKLLMAESDAYANFLSDAAKLESDGLGVENAFETGSLEGGPASESGQSSADALHGVSGDGSSLFYGALEKLGTQCALISEPDELEWNHTGFMLICTRSFKSPIKLIVLGYGSLFL", "length": 642 }, "evidence": [ { "id": "HGNC:20967", "url": "https://alliancegenome.org/gene/HGNC:20967#orthology", "database": "AGR" }, { "id": "MGI:1914080", "url": "https://alliancegenome.org/gene/MGI:1914080#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O35260-1", "protein_name": "Nucleus accumbens-associated protein 1", "gene_name": "Nacc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNSSRSAVVELPAAVQPQSFQQILTFCYTGRLSMNMGDQFLLIYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHPEEAPSSEPQSPVAQILGWPACSTPLPLVSRVKTEQELDSVQCTPMAKRLWDSSQKEAGGSGGNNGSRKMAKFSTPDLAPNRMPQPVSVATATAAVAVVAVGGCVSGPSMSERTSPGTSSAYTSDSPSSYHNEEDEEEDAGEEGTDEQYRQICNMYTMYSMLNVGQTVEKVEALPEQVVLESHSRIRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWLPKTKPLHLVEGDNYSSFISDTGKIEPDMMSMEHSFETASHDGEAGPSAEVLQ", "length": 514 }, "evidence": [ { "id": "HGNC:20967", "url": "https://alliancegenome.org/gene/HGNC:20967#orthology", "database": "AGR" }, { "id": "RGD:621003", "url": "https://alliancegenome.org/gene/RGD:621003#orthology", "database": "AGR" }, { "id": "MGI:1914080", "url": "https://alliancegenome.org/gene/MGI:1914080#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-010319-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-010319-3#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TSZ8-1", "protein_name": "Nucleus accumbens-associated protein 1", "gene_name": "Nacc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNSSRSAVVELPAAVQPQSFQQILTFCYTGRLSMNMGDQFLLIYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHPEEAPSSEPQSPVAQTLGWPACSTPLPLVSRVKTEQELDSVQCTPMAKRLWDSSQKEAGGSGGNNGSRKMAKFSTPDLALNRMPQPLSMATATAAVAVVAVGGCVSGPSMSERTSPGTSSAYTSDSPSSYHNEEDEEEDAGEEGTDEQYRQICNMYTMYSMLNVGQTAEKVEALPEQVVLESRSRIRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWLPKTKPLHLVEGDNYSSFISDTCKIEPDMMSMEHSFETASHDGEAGPSAEVLQ", "length": 514 }, "evidence": [ { "id": "HGNC:20967", "url": "https://alliancegenome.org/gene/HGNC:20967#orthology", "database": "AGR" }, { "id": "RGD:621003", "url": "https://alliancegenome.org/gene/RGD:621003#orthology", "database": "AGR" }, { "id": "MGI:1914080", "url": "https://alliancegenome.org/gene/MGI:1914080#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-010319-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-010319-3#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96RE7-1", "protein_name": "Nucleus accumbens-associated protein 1", "gene_name": "NACC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQTLQMEIPNFGNSILECLNEQRLQGLYCDVSVVVKGHAFKAHRAVLAASSSYFRDLFNNSRSAVVELPAAVQPQSFQQILSFCYTGRLSMNVGDQFLLMYTAGFLQIQEIMEKGTEFFLKVSSPSCDSQGLHAEEAPSSEPQSPVAQTSGWPACSTPLPLVSRVKTEQQESDSVQCMPVAKRLWDSGQKEAGGGGNGSRKMAKFSTPDLAANRPHQPPPPQQAPVVAAAQPAVAAGAGQPAGGVAAAGGVVSGPSTSERTSPGTSSAYTSDSPGSYHNEEDEEEDGGEEGMDEQYRQICNMYTMYSMMNVGQTAEKVEALPEQVAPESRNRIRVRQDLASLPAELINQIGNRCHPKLYDEGDPSEKLELVTGTNVYITRAQLMNCHVSAGTRHKVLLRRLLASFFDRNTLANSCGTGIRSSTNDPRRKPLDSRVLHAVKYYCQNFAPNFKESEMNAIAADMCTNARRVVRKSWMPKVKVLKAEDDAYTTFISETGKIEPDMMGVEHGFETASHEGEAGPSAEALQ", "length": 527 }, "evidence": [ { "id": "HGNC:20967", "url": "https://alliancegenome.org/gene/HGNC:20967#orthology", "database": "AGR" }, { "id": "RGD:621003", "url": "https://alliancegenome.org/gene/RGD:621003#orthology", "database": "AGR" }, { "id": "MGI:1914080", "url": "https://alliancegenome.org/gene/MGI:1914080#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-010319-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-010319-3#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear lumen", "id": "GO:0031981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ89", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ89", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ89", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ89", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ89", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ89", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZ89", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YZ89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" }, { "id": "PS51457", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51457" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BEN", "eco_id": "ECO_0000259", "start_pos": 394, "end_pos": 491, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6YZ89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZ89" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 98, "start_aa": "Cys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 274, "end_pos": 276 }, { "start_pos": 558, "end_pos": 560 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { 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{ "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03602", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03602", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100034556", "url": "https://www.ncbi.nlm.nih.gov/gene/100034556", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100034556", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100034556", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YZA0", "url": "https://www.orthodb.org/?gene=A0A8M6YZA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017212430", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212430", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YZA0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YZA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041210-289", "url": "https://zfin.org/ZDB-GENE-041210-289", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAQALFFLQLVALCSVSECVQHQYYFINQVKNWTEAQRYCRENYTDLATADNMNDTIELIKPVNKARAQNIWIGLRKTSVYTWHWSSGDTVLFLNWASGQPASSNNCTVMRNGHWFDWSCSATCFFICYNTNSGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNESQQLEKFINDRNSSGSAVWIGLFRDTWQWSDHSNSSFRYWNTAEPNNYGGDENCSVIETNAQRGWADNPCHYQFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHNYCSMNMWLWVNGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHTLNFICTNY", "length": 366, "header": "tr|A0A8M6YZA0-1|A0A8M6YZA0_DANRE Isoform 1 of C-type mannose receptor 2 OS=Danio rerio OX=7955 GN=si:ch211-282j17.7 PE=4 SV=1 CANONICAL=A0A8M6YZA0-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YZA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZA0/entry#A0A8M6YZA0-1", "sequence": { "sequence": "MAQALFFLQLVALCSVSECVQHQYYFINQVKNWTEAQRYCRENYTDLATADNMNDTIELIKPVNKARAQNIWIGLRKTSVYTWHWSSGDTVLFLNWASGQPASSNNCTVMRNGHWFDWSCSATCFFICYNTNSGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNESQQLEKFINDRNSSGSAVWIGLFRDTWQWSDHSNSSFRYWNTAEPNNYGGDENCSVIETNAQRGWADNPCHYQFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHNYCSMNMWLWVNGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHTLNFICTNY", "length": 366, "header": "tr|A0A8M6YZA0-1|A0A8M6YZA0_DANRE Isoform 1 of C-type mannose receptor 2 OS=Danio rerio OX=7955 GN=si:ch211-282j17.7 PE=4 SV=1 CANONICAL=A0A8M6YZA0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100034556", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100034556", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1N7C8-1", "protein_name": "CLECT_1 and CLECT domain-containing protein isoform X1", "gene_name": "si:ch211-282j17.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYSSLLLIALCSISECVQHQYYYINVNKTWTEAQRYCREKYTDLATIDNMNELNNMNKLVKSENNGATEYVWTGLQRMSVYKWHWSSGDPALLLNWASGQPAGSDDCAVMRNGQWFDEPCSKTWIFICYNTNTGLVFVDQLMNWRAAQSYCRQNHIDLVSVRNQNESQQLEKFINDRNSSGSAVWIGLFRDTWQWSDQSNSSFRYWNTAEPNNAGGIQNCIGMNQNAQGRWHDISCTGSFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHNYCSMNMWLWVNGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHRLNFICTNY", "length": 370 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1NE49-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-83f18.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQSLFFPLLLIALCSISECVQRQYHFINENKNWTEAQRYCREKYTDLATVDNMNDMIQLNKSVNNVNNQNIYIGLQKTNVSKWHWSSGDLVLFLNWASGEPNNSYNCGTIKNGQWFAESCNNTCFFICYNMSRGLVFVNQNMNWTVAQSYCRQNHIDLVTVRNQNESQQLEKFINDRNSSGSAVWIGLFRDTWQWSDQSNSSFRYWAANFKDSSYSAAIQPNISGQWADYSSNYNQFPFVCHEDKLIVIQQTKSWSEALRYCRQNHVDLVSVQSVEMQYEVMNVVKLASTEAVWLGLRHSCALGIWFWVSGQTVCYQYWAPGNGTSEEDCEPTVRSGAVQSGGDQTWISRPEIDKLNFICRNY", "length": 364 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1P3G7-1", "protein_name": "Uncharacterized protein LOC555551 isoform 1 precursor", "gene_name": "si:dkey-88n24.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQSLYFPLHLIALCSISECVQRQYHFINENKNWTEAQRYCREKYTDLATVDNMNDLIQLKKSANNEGVQNIWIGLQRTGVYKWYWSSGDPALFLNWASGEPAGSEECAVMRNGQWIVWLCSNVSFFICNNTSTGLVFVNQSMTWREAQSYCRQNHIDLVSVRNQNENQQLEKFINDRNSSGSAVWIGLFRDTWQWLDQSNSSFRYWYPGEPNNYGGHEDCAVIGKNTQRGWADVPCDSRQIPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHHYCSMNMWLWVSGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGNQTWISLPESHRLNFICTNY", "length": 368 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RF17-1", "protein_name": "C-type mannose receptor 2", "gene_name": "si:ch211-225k7.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQSLYFPLLLIALCSISECVQRQYHFINEKKTWTEAQRYCREKYTDLATVDNMNDTTELMKSVYDVRLWIGLQRKWQWSSGGPALFLNWGYNQPDGSDECAFMKNGVWHDGKCSDTWIFVCYNMSRGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNENQQLENFINDRNSSGSAVWIGLFRDSWQWSDQSTYSFSYWNNQEPNNVGGNENCTVLMENTQGHWADISCDRQFPFVCHEDKLIVIQQNLSWSEALRYCRQHHVDLVSVQSVEMQYEVMNVVKLASTEAVWLGLRFSHILGIWFWVSGETVYYRNWAPGNGTSEEDCEPTVRSGAVQSGGNQTWISRPETDKLNFICSRYE", "length": 361 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q208-1", "protein_name": "Macrophage mannose receptor 1", "gene_name": "si:ch211-225k7.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYFPLLLIALCSISECVQRQYHFIHEKKTWTEAQRYCREKYTDLATVDNMNDTIQLMKSVNDERIWIGLQRKWQWSSGDPALFLNWAYRQPDGKDECAFMINGEWHDGACSNTLFFICYNMSRGLVFVDQMMNWRDAQSYCRQNHTDLVTVRNQNESQQLEKFINDSNSSGSAVWIGLFRDWQWSDQSNYSFRYWDTNQPDNQGGTENCAVITQNVQGRWNDISCDHQFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLRFSHILGIWYWVSGETVFYQNWAPGNGTSEEDCEPTVRSGAVQSGGSQTWISRPETDRLNFICSRYG", "length": 360 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TYY6-1", "protein_name": "C-type mannose receptor 2", "gene_name": "si:dkey-192d15.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQAQYILLLIALCSISECVQRQYHFINEKKNLTEAQRYCRENYTDLATVDNMNNMIQLNKSVNDERVWIGLQRTSVYKWHWSSGDPALFLNWASGQPVGSDNCTYMTNGQWIVGPCSAISPFICYNMSRGLVFVNQTVNWRAAQSYCRQNHTDLVIVRNQNESQQLEQFINDRQLSGGAIWIGLFRDPWQWSDQSNSSFRYWKTTEPDNYGGIENCTVIEENAQGRWADYPCYWKMPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHHYCSMNMWLWLTGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHRLNFICTN", "length": 362 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LXV6-1", "protein_name": "C-type lectin domain containing 20A", "gene_name": "Clec20a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWYCQEHYTDLADLQSMNSLVSVMVVYSYTSSVQAWIGLFYDVRISGLSWSSGSVFTMPTWSKLPVFQDGVCATLYSWYGVPALGAASCTGQKPFICYFDPAVGHRISLVSPLKDLTTLPEEAEVKIGGQTFIRIKQTMTWLSALTYCRHHYTDLADLQRVTDKDKDSLKPVINGDDAWIGLYFSVKINHLTWSSDQGSSIPEWLQEMPMFGQGLCAGIRTFANHPPQIYALLCPDLKPFICFNDPSIGHRQSAEMPSLIDTSSPRVTQHSKVPTRTTSRPNTGTSTDSTDASQVLDSASWIPRQVSHEPTAVSSGTCGFRTCDTTTPASTTVGLTALQSQGMVSIRPVATSAYPGETKERTTEASVSGSTAEVQGNWTSVPAAWNPDTSTGTAGSLPGTTTAMTTVEGGIYKGDTTSATEAQHLCSPKYPESKKKAAASESEHSFGILKADFAIPALRDPEEMKDQLLSEIQEVLKLILGHEEFTLKWIGSEVNKK", "length": 497 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58G2Y2-1", "protein_name": "C-type mannose receptor 2-like isoform X1", "gene_name": "si:dkey-28d5.15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKHSEAFSLKQISEMAQKLQFFLLLIALCSISECVQRQYHFINEMKTWTEAQRYCREKYTDLATVDSMNDTTELMKIVNNVRLWIGLERKWQWSSGDPVLFLNWGDKQPDGKDECAFMRNGEWHDWPCNKDCFFVCYNRSRGLVFVNERKNWTDAQSHCRLHYTDLVSVRNQNENQQLEKFINDSPKPEPGSDVWIGLFRDSWQWSDQSNYSFSNWKLGEPNNVGDHENCTAVEKDAQGQWIDISCDHQLPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYEVMSDVKKASTEAVWLGLRFSHILGIWFWVSGETVCYQNWAPGNGTSEENCEATVRSGAVQSGGDQTWISRPETHKLNFICSKY", "length": 377 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58H6E4-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkeyp-94g1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKSKKEKSSTVSQWVAQSPHSKKVTGSSPSRRGSGVMHESLFMLLLLSGLLRMNSELYRDYYFINIRMSWPEAQSYCRAKYTDLATAESTDDVNRLLNSVGAQYNGSVWIGLKRGTQKRWGWSYGDNTIAQYTAWSNGEPSSTNECGFLAYGNWRTYNCSDLIYFACYNGTGYTMLTMWMNWTDAQSYCRKHYIDLPTIHNSTELAQINSAVSYNAWLWIGLFKDSWEWSDKWGWFFRYWAVGQPSPSAGSSDCVGMSTTNFGKWASYSCGLQQPFICYGGTKFPYIYQYVNKSMTWPDAQSYCRARFTDLATVDTMDDVNRLVNIVDPGFSGSVWIGLQNGGQNRWIWSLGNGVLSTYSFWNPGEPSGDGDCGSSTYGNWSDESCSTVLPFLCFDDHTGFAIINTAMTWRDAQSYCRHYHTDLATIDSVDQQHMISTQSTLWIGLFLDSWGWSDQDILSFRYWAPDQPPLSSVSGDCAGLSTADFGQWAQYSCNLQQNFICYGDDSLINKQIVHIKLSCKDKCTPNDPTLQTAFLNKINEKLRSLGLERKSKISWKQSEDEEVFHEETYPPTNY", "length": 575 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WUG5-1", "protein_name": "Uncharacterized protein LOC558654 precursor", "gene_name": "si:ch211-225k7.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYFPLLLIALCSISECVQRQYHFINENKTWTEAQRYCREKYTDLATVDNMNDTIQLNKSVNDVRLWIGLQRKWQWSSGDPELFLNWESGQPDGKDECAFMRHGKWHDGKCSDTWFVICYNMSRGLVFVNQTMNWRAAQSYCRQNHIDLVSVRNQNESQQLEKFINDSIPSRSDVWIGLFRDWQWSDQSNYSFSYWNTNEPNNYGNNENCTVLKENTNGHWADISCDCQFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYKVMNVVKLASTGAVWLGLRHSCALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRSGAVQSGGDQTWISRPETDRLNFICRNY", "length": 359 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WUJ5-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-83f18.11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGQFLDSLLLLVALCSISECVQRQYHFINEMKTWTEAQRYCREKYTDLATVDNMNDMIQLMKSVKVNDRGVWIGLQRKWQWSSGDPALFLHWGNEQPDGADECAFMRNGQWEDGKCNDSWIFVCYNMSRGLVFVNQAMTWRAAQSYCRQNHTDLVSVRNQNESQQLEKFINDSHKFASEVWIGLFRDSWQWSDRSNYSFSYWNNQEPNDYGGKENCTVVQPKTEGRWNDIVCNNLFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYKVMNVVKLASTEAVWLGLRHSCALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRSGAVQSGGSQTWISRPETHKLNFICRNY", "length": 362 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F6PDD5-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-81n2.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYIPLLLIALCSISECVQRQYHFINEGRNQTEAQKYCREKYTDLATVDNMSDMNQLIKSVNNGGVENIWIGLQRTSVYKWHWSSGDPVLFLNWTSGEPAGSNECTVMHNGQWINEACSNTRFFICYNMSTGLVFVDQMMNWRDAQSYCRQNHTDLVSVRNQNENQQLEKFINDRNSSGAEVWIGLFRDSWQWSDQSNSSFRYWNTGEPNNVEESCAVIGKNPQRGWADVLCDGRKIPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYKVMNVVKLASTEAVWLGLRHSCALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRSGAVQSGGNQTWISRPETDRLNFICRNY", "length": 366 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1L8A7-1", "protein_name": "Uncharacterized protein LOC555932 precursor", "gene_name": "si:ch73-335d12.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYLSLLLIALCSISECVQRQYHFINKNKTWTEAQRYCREKYTDLATVDNMNDMIQMNKSVKVNDGYAWIGLQRTSVYKWHWSSGDSVLFLNWASGQPAGGDNCTVMRNGKWFVEPCSDAWTFICYNMSRGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNENQQLEKFINDRNSSGSAVWIGLFRDTWQWSDQSNSSFRYWDTIEPNNAGGHENCAVIYLYNLKQWNDILCDRQYAFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHNFCSMNMWLWLSGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHRLNFICTNY", "length": 366 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZU45-1", "protein_name": "Putative C-type lectin domain family 20 member A", "gene_name": "CLEC20A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPRALLLSFCAAALQLVSSKRDLVLVKEALSWYDAQQHCRLHYTDLADLQPSGLWKLYSLMTSTPAWIGLFFDASTSGLRWSSGSTFTALEWGQKLPEFGVGFCATLYTWLKLPSIGAASCTAQKPFLCYCDPDVGHLISTKPSLSLTTSPKPAVVQISGQTFMRFDQVMTWSSALLYCRSHHTDLADLQMVTDETGKEALRSIMSETEAWIGLYLNANSGSLSWSSDLGASIPSWLQVPMMVRGLCTALGIYMTYSPKVYSVNCSSLLPFFCFYDSSTGHRASAELPPLFHTSPTEMTEETTPRPGRAVASVGSGTDRRDTAAATEAQHLSSESKEKTSAQKSGHPFGILKADFTISTLMDPEEMKDQFLRQIQEVLKLTLGHEQFRLKWVSFEVNKK", "length": 400 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-289", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-289#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YZA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZA0" }, { "id": "PS50041", "database": "PROSITE", "url": 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YZF9-1", "uniprot_ac": "A0A8M6YZF9", "uniprot_id": "A0A8M6YZF9_DANRE", "mass": { "chemical_mass": 111684.0, "monoisotopic_mass": 111684.0 }, "refseq": { "ac": "XP_017211875", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211875" }, "gene_names": [ { "name": "LOC101882342", "type": "recommended", "evidence": [ { "id": "A0A8M6YZF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9" } ] }, { "name": "LOC101882342", "type": "synonym", "evidence": [ { "id": "XP_017211875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211875" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6YZF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017211875", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211875" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017211875.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211875", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211875" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101882342", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9", "locus": {} } ], "crossref": [ { "id": "A0A8M6YZF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YZF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101882342", "url": "https://www.ncbi.nlm.nih.gov/gene/101882342", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101882342", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882342", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YZF9", "url": "https://www.orthodb.org/?gene=A0A8M6YZF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10075:SF103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10075:SF103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017211875", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211875", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YZF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YZF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JMM2", "url": "https://www.uniprot.org/uniprotkb/A0AC58JMM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JMM2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JMM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRASMFRPVWSSLQTPSSLWLFLLASSIRINPAALELVFAILPEDGVGILNSSLMLHCAAFDSVLKFPVPVKWEKNTRGLDRRSQQMANGSLFFPRLQEEDFGNYSCSAKRGNKQIQTTVMVSKACLQDVFFHPQSMQTEEGRDVFLQCVSGDSFPPAQISWLKNGRVLTKGNQIQGQYGGGSQRKTSGTLHLANVTKADQGIYICLTRNHLLNISKESHAAALTVHGSNVDVSIIEGPQNVTVPVEMEAALHCIVEGFPIPIVQWFKDGNPLHDSSRLDLQKDGQLLIFQRVLPEDEGLYFCEAHNQKAKVKSQPAYLLPAERPSVSIWPVQVTSPVGAEVLIHCQVSGLPAPVLTWSKQGQSVQTGGKILMGLRNTTLLISSVRVYDEGRYTCSASNTLGHDEKTMTLRVAVKPVIVSFTPSVAVSEGSPVSLPCRAVGESPVKYTWTKLSDPKSPVSLPQHIHIDDNGTLVISTIQRSDSGDYQCTAENRAGQGARRVTITVTDPDVPPDKEALSKTAKPTVLESEQELFTLYGSKLLNNTEINEPLHQTTEDYARISLLNAFVEDSPTYLNPESTQDTTERISLKSSGIGIESNENMKEPVQTQKPTPVRVKPTPLTQLKETTVLQDTHPQIQPTEQLTKAPPQMNTNTNSPSAADSYSQSQLKHAQSFSRNSGETQTVMNVGNLTGSASVEEHQNQSQIKSEAKTSATNDTDLVETPKKNTSQAPMRTTDNNNREKGKSQTWLPVIEKHDIPIVVGVGVSLAFIFISMAFYSLVQKNDPAVVPTGRAALRGLCGPCRQGDRHAMEMTYDNKAFEDDNLVAVIEQSPNNSETRALPTESNSSVFDVVDVDEGVRSIQDLPVIVETHPEPREEDQLETIFEEGKVSPSPHTDVQLQCMEDWRSREFEPCQDASSLPPPNPAPAQEEGLRSSLTLRTTDPSSTPVRHSISISHGVSPLLLSHCVSLGMTSVAVDVHFYPSAPLAATNPAFGAPVQQLNTRLEHELTAPSAGSVNNKIV", "length": 1021, "header": "tr|A0A8M6YZF9-1|A0A8M6YZF9_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101882342 PE=4 SV=3 CANONICAL=A0A8M6YZF9-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YZF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9/entry#A0A8M6YZF9-1", "sequence": { "sequence": "MKRASMFRPVWSSLQTPSSLWLFLLASSIRINPAALELVFAILPEDGVGILNSSLMLHCAAFDSVLKFPVPVKWEKNTRGLDRRSQQMANGSLFFPRLQEEDFGNYSCSAKRGNKQIQTTVMVSKACLQDVFFHPQSMQTEEGRDVFLQCVSGDSFPPAQISWLKNGRVLTKGNQIQGQYGGGSQRKTSGTLHLANVTKADQGIYICLTRNHLLNISKESHAAALTVHGSNVDVSIIEGPQNVTVPVEMEAALHCIVEGFPIPIVQWFKDGNPLHDSSRLDLQKDGQLLIFQRVLPEDEGLYFCEAHNQKAKVKSQPAYLLPAERPSVSIWPVQVTSPVGAEVLIHCQVSGLPAPVLTWSKQGQSVQTGGKILMGLRNTTLLISSVRVYDEGRYTCSASNTLGHDEKTMTLRVAVKPVIVSFTPSVAVSEGSPVSLPCRAVGESPVKYTWTKLSDPKSPVSLPQHIHIDDNGTLVISTIQRSDSGDYQCTAENRAGQGARRVTITVTDPDVPPDKEALSKTAKPTVLESEQELFTLYGSKLLNNTEINEPLHQTTEDYARISLLNAFVEDSPTYLNPESTQDTTERISLKSSGIGIESNENMKEPVQTQKPTPVRVKPTPLTQLKETTVLQDTHPQIQPTEQLTKAPPQMNTNTNSPSAADSYSQSQLKHAQSFSRNSGETQTVMNVGNLTGSASVEEHQNQSQIKSEAKTSATNDTDLVETPKKNTSQAPMRTTDNNNREKGKSQTWLPVIEKHDIPIVVGVGVSLAFIFISMAFYSLVQKNDPAVVPTGRAALRGLCGPCRQGDRHAMEMTYDNKAFEDDNLVAVIEQSPNNSETRALPTESNSSVFDVVDVDEGVRSIQDLPVIVETHPEPREEDQLETIFEEGKVSPSPHTDVQLQCMEDWRSREFEPCQDASSLPPPNPAPAQEEGLRSSLTLRTTDPSSTPVRHSISISHGVSPLLLSHCVSLGMTSVAVDVHFYPSAPLAATNPAFGAPVQQLNTRLEHELTAPSAGSVNNKIV", "length": 1021, "header": "tr|A0A8M6YZF9-1|A0A8M6YZF9_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101882342 PE=4 SV=3 CANONICAL=A0A8M6YZF9-1" }, "locus": {} }, { "isoform_ac": "A0AC58JMM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9/entry#A0AC58JMM2-1", "sequence": { "sequence": "MLHCAAFDSVLKFPVPVKWEKNTRGLDRRSQQMANGSLFFPRLQEEDFGNYSCSAKRGNKQIQTTVMVSKACLQDVFFHPQSMQTEEGRDVFLQCVSGDSFPPAQISWLKNGRVLTKGNQIQGQYGGGSQRKTSGTLHLANVTKADQGIYICLTRNHLLNISKESHAAALTVHGSNVDVSIIEGPQNVTVPVEMEAALHCIVEGFPIPIVQWFKDGNPLHDSSRLDLQKDGQLLIFQRVLPEDEGLYFCEAHNQKAKVKSQPAYLLPAERPSVSIWPVQVTSPVGAEVLIHCQVSGLPAPVLTWSKQGQSVQTGGKILMGLRNTTLLISSVRVYDEGRYTCSASNTLGHDEKTMTLRVAVKPVIVSFTPSVAVSEGSPVSLPCRAVGESPVKYTWTKLSDPKSPVSLPQHIHIDDNGTLVISTIQRSDSGDYQCTAENRAGQGARRVTITVTDPDVPPDKEALSKTAKPTVLESEQELFTLYGSKLLNNTEINEPLHQTTEDYARISLLNAFVEDSPTYLNPESTQDTTERISLKSSGIGIESNENMKEPVQTQKPTPVRVKPTPLTQLKETTVLQDTHPQIQPTEQLTKAPPQMNTNTNSPSAADSYSQSQLKHAQSFSRNSGETQTVMNVGNLTGSASVEEHQNQSQIKSEAKTSATNDTDLVETPKKNTSQAPMRTTDNNNREKGKSQTWLPVIEKHDIPIVVGVGVSLAFIFISMAFYSLVQKNDPAVVPTGRAALRGLCGPCRQGDRHAMEMTYDNKAFEDDNLVAVIEQSPNNSETRALPTESNSSVFDVVDVDEGVRSIQDLPVIVETHPEPREEDQLETIFEEGKVSPSPHTDVQLQCMEDWRSREFEPCQDASSLPPPNPAPAQEEGLRSSLTLRTTDPSSTPVRHSISISHGVSPLLLSHCVSLGMTSVAVDVHFYPSAPLAATNPAFGAPVQQLNTRLEHELTAPSAGSVNNKIV", "length": 966, "header": "tr|A0AC58JMM2-1|A0AC58JMM2_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC101882342 PE=4 SV=1 CANONICAL=A0A8M6YZF9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101882342", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882342", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9" } ], "pmid": "" }, { "name": "axon guidance", "id": "GO:0007411", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007411", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9" } ], "pmid": "" }, { "name": "dendrite self-avoidance", "id": "GO:0070593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070593", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell-cell adhesion mediator activity", "id": "GO:0098632", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098632", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 471, "end_pos": 473, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 689, "end_pos": 691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 701, "end_pos": 703, "annotation": "n_glycosylation_sequon" }, { "start_pos": 715, "end_pos": 717, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 835, "annotation": "n_glycosylation_sequon" }, { "start_pos": 845, "end_pos": 847, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YZF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF9" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 33, "end_pos": 124, "start_aa": "Pro", "end_aa": "Ser", 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017212615", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212615" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZJ7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108190731", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZJ7", "locus": {} } ], "crossref": [ { "id": "108190731", "url": "https://www.ncbi.nlm.nih.gov/gene/108190731", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017212100.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017212100", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212100" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0AC58FYP2", "url": "https://www.uniprot.org/uniprotkb/A0AC58FYP2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-202h22.10", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110914-121", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110914-121", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YZP9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YZP9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100002322", "url": "https://www.ncbi.nlm.nih.gov/gene/100002322", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100002322", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100002322", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YZP9", "url": "https://www.orthodb.org/?gene=A0A8M6YZP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390:SF260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390:SF260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017212100", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212100", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YZP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YZP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58FYP2", "url": "https://www.uniprot.org/uniprotkb/A0AC58FYP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58FYP2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58FYP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110914-121", "url": "https://zfin.org/ZDB-GENE-110914-121", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLISDQKELTEDSATCRQSGKHTFKEGSIEKTMRIPTEEKPFICPECGKCFSAKQKLETHIRIHTGEKPFSCPQCGKGFTQQGQIKTHMRIHTGEKPFTCPQCDKSVTSKQSLKSHMRIHTGEKPFTCPECGMIFSQLGYLKRHVRTHTGLKPFSCTQCGKRYKVKQSLESHMRVHTGEKPFACPQCGKGFTAKQCLKSHMSVHIEEKPFNCSLCEMSFTHQQSLKRHMLIHVGEKPYVCRQCGKSFSVKQSLESHIRIHTGEKPFACAECGKGFAVKQNLESHMRVHTGVKPFSCPQCGKRFTVKQSLESHMTIHTGERPFTCSMCDKTFTVKHKLEYHMRNHTGEKPYICPQCGNSYALRNHLERHVRIHTGEKPFSCSKCAKRFTMKQSLKSHMRVHNRTKPYICSQCGKRFTVKQSLESHMSLHTGEKPFTCTECGKSYTLRQSLETHMRVHTGDKCFSCSDCGRSFTVKQNLHVHMRVHTGERPYTCAQCGKRFTQHGQLNRHMRIHTEQKTTRDRSEETLNDETADNSSDIQHQSEEKDVVTVLI", "length": 551, "header": "tr|A0A8M6YZP9-1|A0A8M6YZP9_DANRE Isoform 1 of Uncharacterized protein si:ch211-202h22.10 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-202h22.10 PE=3 SV=2 CANONICAL=A0A8M6YZP9-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YZP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9/entry#A0A8M6YZP9-1", "sequence": { "sequence": "MLISDQKELTEDSATCRQSGKHTFKEGSIEKTMRIPTEEKPFICPECGKCFSAKQKLETHIRIHTGEKPFSCPQCGKGFTQQGQIKTHMRIHTGEKPFTCPQCDKSVTSKQSLKSHMRIHTGEKPFTCPECGMIFSQLGYLKRHVRTHTGLKPFSCTQCGKRYKVKQSLESHMRVHTGEKPFACPQCGKGFTAKQCLKSHMSVHIEEKPFNCSLCEMSFTHQQSLKRHMLIHVGEKPYVCRQCGKSFSVKQSLESHIRIHTGEKPFACAECGKGFAVKQNLESHMRVHTGVKPFSCPQCGKRFTVKQSLESHMTIHTGERPFTCSMCDKTFTVKHKLEYHMRNHTGEKPYICPQCGNSYALRNHLERHVRIHTGEKPFSCSKCAKRFTMKQSLKSHMRVHNRTKPYICSQCGKRFTVKQSLESHMSLHTGEKPFTCTECGKSYTLRQSLETHMRVHTGDKCFSCSDCGRSFTVKQNLHVHMRVHTGERPYTCAQCGKRFTQHGQLNRHMRIHTEQKTTRDRSEETLNDETADNSSDIQHQSEEKDVVTVLI", "length": 551, "header": "tr|A0A8M6YZP9-1|A0A8M6YZP9_DANRE Isoform 1 of Uncharacterized protein si:ch211-202h22.10 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-202h22.10 PE=3 SV=2 CANONICAL=A0A8M6YZP9-1" }, "locus": {} }, { "isoform_ac": "A0AC58FYP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9/entry#A0AC58FYP2-1", "sequence": { "sequence": "MRIPTEEKPFICPECGKCFSAKQKLETHIRIHTGEKPFSCPQCGKGFTQQGQIKTHMRIHTGEKPFTCPQCDKSVTSKQSLKSHMRIHTGEKPFTCPECGMIFSQLGYLKRHVRTHTGLKPFSCTQCGKRYKVKQSLESHMRVHTGEKPFACPQCGKGFTAKQCLKSHMSVHIEEKPFNCSLCEMSFTHQQSLKRHMLIHVGEKPYVCRQCGKSFSVKQSLESHIRIHTGEKPFACAECGKGFAVKQNLESHMRVHTGVKPFSCPQCGKRFTVKQSLESHMTIHTGERPFTCSMCDKTFTVKHKLEYHMRNHTGEKPYICPQCGNSYALRNHLERHVRIHTGEKPFSCSKCAKRFTMKQSLKSHMRVHNRTKPYICSQCGKRFTVKQSLESHMSLHTGEKPFTCTECGKSYTLRQSLETHMRVHTGDKCFSCSDCGRSFTVKQNLHVHMRVHTGERPYTCAQCGKRFTQHGQLNRHMRIHTEQKTTRDRSEETLNDETADNSSDIQHQSEEKDVVTVLI", "length": 519, "header": "tr|A0AC58FYP2-1|A0AC58FYP2_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-202h22.10 isoform X2 OS=Danio rerio OX=7955 GN=si:ch211-202h22.10 PE=3 SV=1 CANONICAL=A0A8M6YZP9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100002322", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100002322", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP9" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 69, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 533, "end_pos": 535 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YZS3-1", "uniprot_ac": "A0A8M6YZS3", "uniprot_id": "A0A8M6YZS3_DANRE", "mass": { "chemical_mass": 90158.0, "monoisotopic_mass": 90158.0 }, "refseq": { "ac": "XP_017210797", "name": "sortilin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210797" }, "gene_names": [ { "name": "si:dkey-159a18.1", "type": "recommended", "evidence": [ { "id": "A0A8M6YZS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3" } ] }, { "name": "si:dkey-159a18.1", "type": "synonym", "evidence": [ { "id": "XP_017210797", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210797" } ] } ], "protein_names": [ { "name": "Sortilin isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6YZS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3/entry#names_and_taxonomy" } ] }, { "name": "sortilin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017210797", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210797" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017210797", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210797" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZS3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-159a18.1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3", "locus": {} } ], "crossref": [ { "id": "A0A8M6YZS3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YZS3", "database": "AlphaFoldDB", "categories": [] }, { "id": "560593", "url": "https://www.ncbi.nlm.nih.gov/gene/560593", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031778", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031778", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:560593", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560593", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YZS3", "url": "https://www.orthodb.org/?gene=A0A8M6YZS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7T5T0", "url": "https://www.orthodb.org/?gene=A0A8N7T5T0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12106:SF46", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12106:SF46", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15902", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15902", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017210797", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210797", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YZS3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YZS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7T5T0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T5T0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7T5T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T5T0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J9V9", "url": "https://www.uniprot.org/uniprotkb/A0AC58J9V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J9V9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J9V9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKWILLVFGSVCLLDVVEDSFVHGKRNARTVTFSRTGRGQSRRRRDTWTTEKERFTECNTPLSVKDRELLRSHTHETGFHGDDGSSFTLTWAGNGTGIIFVLSTISVPSDSFYEGGSSRLYRSEDYGKSFHDISHAINNTFLNSYFGISAGHGNPQPVILTANLPFTKDPGGKIFTSMDAGLTFRSVQLQFHPAQAIQFSLLDPKYLVVISIDDGLWLSEDFGNNWSKVHEGVHTFTWGSENTLFFSSSPNGTVEAARRGELILRRTCDFGKTFDTIAENIFSFGHIGSFLFTSVMEKLGSPRVIYVSKDQGDHFKRAQLPSATTEQFYSVLDADEDMIFMHVDNPGEDTYYGTVYASDEQGILYSKSLERHLFGGEGKSDFTNITSLRGVYLTNILEEGGCIRSVISFNRGGRWRYLKKPENVDCPDMSKKCNLHIHGEHSHFSGVTPMTPSSEPTAIGLVIGHGSVGDSISAARPDVYVSRDGGYTWWGTLRGPHHYSILDSGGLIVAVEARRDRGISSIKFSTDEGQCWKTFNFTDHPFFLAGLASEPSSSTMNISIFGYRLDDNHKPMWVAVTIDFEHLLTRECNDQDYVTWLAHSNYSSNPKTDGCLLGYKETFRRLKTLSACRNGRGYVVSRQQSPCICTSEDFMCDYGFYWHENSSACLPQPDFLNQTQDFCLNVDLQTTGYRRIPGDKCKGSFSPPRNEEAHQKLCGNVTSSDSHTEIPPAILALIVVCSLGIICLVIIAAYMITSRRINCGQRSPEYNFSVLQIQEDDLSVNNESTPNGKLNGFQVQEDSDDVSLIKQ", "length": 807, "header": "tr|A0A8M6YZS3-1|A0A8M6YZS3_DANRE Isoform 1 of Sortilin isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-159a18.1 PE=3 SV=1 CANONICAL=A0A8M6YZS3-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YZS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3/entry#A0A8M6YZS3-1", "sequence": { "sequence": "MKWILLVFGSVCLLDVVEDSFVHGKRNARTVTFSRTGRGQSRRRRDTWTTEKERFTECNTPLSVKDRELLRSHTHETGFHGDDGSSFTLTWAGNGTGIIFVLSTISVPSDSFYEGGSSRLYRSEDYGKSFHDISHAINNTFLNSYFGISAGHGNPQPVILTANLPFTKDPGGKIFTSMDAGLTFRSVQLQFHPAQAIQFSLLDPKYLVVISIDDGLWLSEDFGNNWSKVHEGVHTFTWGSENTLFFSSSPNGTVEAARRGELILRRTCDFGKTFDTIAENIFSFGHIGSFLFTSVMEKLGSPRVIYVSKDQGDHFKRAQLPSATTEQFYSVLDADEDMIFMHVDNPGEDTYYGTVYASDEQGILYSKSLERHLFGGEGKSDFTNITSLRGVYLTNILEEGGCIRSVISFNRGGRWRYLKKPENVDCPDMSKKCNLHIHGEHSHFSGVTPMTPSSEPTAIGLVIGHGSVGDSISAARPDVYVSRDGGYTWWGTLRGPHHYSILDSGGLIVAVEARRDRGISSIKFSTDEGQCWKTFNFTDHPFFLAGLASEPSSSTMNISIFGYRLDDNHKPMWVAVTIDFEHLLTRECNDQDYVTWLAHSNYSSNPKTDGCLLGYKETFRRLKTLSACRNGRGYVVSRQQSPCICTSEDFMCDYGFYWHENSSACLPQPDFLNQTQDFCLNVDLQTTGYRRIPGDKCKGSFSPPRNEEAHQKLCGNVTSSDSHTEIPPAILALIVVCSLGIICLVIIAAYMITSRRINCGQRSPEYNFSVLQIQEDDLSVNNESTPNGKLNGFQVQEDSDDVSLIKQ", "length": 807, "header": "tr|A0A8M6YZS3-1|A0A8M6YZS3_DANRE Isoform 1 of Sortilin isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-159a18.1 PE=3 SV=1 CANONICAL=A0A8M6YZS3-1" }, "locus": {} }, { "isoform_ac": "A0A8N7T5T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3/entry#A0A8N7T5T0-1", "sequence": { "sequence": "MKWILLVFGSVCLLDVVEDSFVHGKRNARTVTFSRTGRGQSRRRRDTWTTEKERFTECNTPLSVKDRELLRSHTHETGFHGDDGSSFTLTWAGNGTGIIFVLSTISVPSDSFYEGGSSRLYRSEDYGKSFHDISHAINNTFLNSYFGISAGHGNPQPVILTANLPFTKDPGGKIFTSMDAGLTFRSVQLQFHPAQAIQFSLLDPKYLVVISIDDGLWLSEDFGNNWSKVHEGVHTFTWGSENTLFFSSSPNGTVEAARRGELILRRTCDFGKTFDTIAENIFSFGHIGSFLFTSVMEKLGSPRVIYVSKDQGDHFKRAQLPSATTEQFYSVLDADEDMIFMHVDNPGEDTYYGTVYASDEQGILYSKSLERHLFGGEGKSDFTNITSLRGVYLTNILEEGGCIRSVISFNRGGRWRYLKKPENVDCPDMSKKCNLHIHGEHSHFSGVTPMTPSSEPTAIGLVIGHGSVGDSISAARPDVYVSRDGGYTWWGTLRGPHHYSILDSGGLIVAVEARRDRGISSIKFSTDEGQCWKTFNFTDHPFFLAGLASEPSSSTMNISIFGYRLDDNHKPMWVAVTIDFEHLLTRECNDQDYVTWLAHSNYSSNPKTDGCLLGYKETFRRLKTLSACRNGRGYVVSRQQSPCICTSEDFMCDYGFYWHENSSACLPQPDFLNQTQDFCLNVDLQTTGYRRIPGDKCKGSFSPPRNEEAHQKLCGNVTSSDSHTEIPPAILALIVVCSLGIICLVIIAAYMITSRRINCGQRSPEYNFSVLQIQEDDLSVNNESTPNGKLNGFQVQEDSDDDLLE", "length": 805, "header": "tr|A0A8N7T5T0-1|A0A8M6YZS3_DANRE Computationally mapped isoform of Sortilin isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-159a18.1 PE=3 SV=1 CANONICAL=A0A8M6YZS3-1" }, "locus": {} }, { "isoform_ac": "A0AC58J9V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3/entry#A0AC58J9V9-1", "sequence": { "sequence": "MDAGLTFRSVQLQFHPAQAIQFSLLDPKYLVVISIDDGLWLSEDFGNNWSKVHEGVHTFTWGSENTLFFSSSPNGTVEAARRGELILRRTCDFGKTFDTIAENIFSFGHIGSFLFTSVMEKLGSPRVIYVSKDQGDHFKRAQLPSATTEQFYSVLDADEDMIFMHVDNPGEDTYYGTVYASDEQGILYSKSLERHLFGGEGKSDFTNITSLRGVYLTNILEEGGCIRSVISFNRGGRWRYLKKPENVDCPDMSKKCNLHIHGEHSHFSGVTPMTPSSEPTAIGLVIGHGSVGDSISAARPDVYVSRDGGYTWWGTLRGPHHYSILDSGGLIVAVEARRDRGISSIKFSTDEGQCWKTFNFTDHPFFLAGLASEPSSSTMNISIFGYRLDDNHKPMWVAVTIDFEHLLTRECNDQDYVTWLAHSNYSSNPKTDGCLLGYKETFRRLKTLSACRNGRGYVVSRQQSPCICTSEDFMCDYGFYWHENSSACLPQPDFLNQTQDFCLNVDLQTTGYRRIPGDKCKGSFSPPRNEEAHQKLCGNVTSSDSHTEIPPAILALIVVCSLGIICLVIIAAYMITSRRINCGQRSPEYNFSVLQIQEDDLSVNNESTPNGKLNGFQVQEDSDDDLLE", "length": 628, "header": "tr|A0AC58J9V9-1|A0AC58J9V9_DANRE Computationally mapped isoform of Sortilin isoform X3 OS=Danio rerio OX=7955 GN=si:dkey-159a18.1 PE=4 SV=1 CANONICAL=A0A8M6YZS3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:560593", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560593", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZS3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZS3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZS3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZS3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "endocytosis", "id": "GO:0006897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006897", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZS3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3" } ], "pmid": "" }, { "name": "vesicle organization", "id": "GO:0016050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016050", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZS3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZS3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 661, "end_pos": 663, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 716, "end_pos": 718, "annotation": "n_glycosylation_sequon" }, { "start_pos": 767, "end_pos": 769, "annotation": "n_glycosylation_sequon" }, { "start_pos": 782, "end_pos": 784, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YZS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZS3" }, { "id": "SM00602", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00602" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VPS10", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 719, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 225, "end_pos": 227 }, { "start_pos": 251, "end_pos": 253 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 557, "end_pos": 559 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 661, "end_pos": 663 }, { "start_pos": 673, "end_pos": 675 }, { "start_pos": 716, "end_pos": 718 }, { "start_pos": 767, "end_pos": 769 }, { "start_pos": 782, "end_pos": 784 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YZT0-1", "uniprot_ac": "A0A8M6YZT0", "uniprot_id": "A0A8M6YZT0_DANRE", "mass": { "chemical_mass": 123015.0, "monoisotopic_mass": 123015.0 }, "refseq": { "ac": "XP_017210817", "name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210817" }, "gene_names": [ { "name": "LOC103910510", "type": "recommended", "evidence": [ { "id": "A0A8M6YZT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT0" } ] }, { "name": "LOC103910510", "type": "synonym", "evidence": [ { "id": "XP_017210817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210817" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017210817", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210817" }, { "id": "A0A8M6YZT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017210817.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017210817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210817" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZT0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC103910510", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT0", "locus": {} } ], "crossref": [ { "id": "A0A8M6YZT0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YZT0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103910510", "url": "https://www.ncbi.nlm.nih.gov/gene/103910510", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:103910510", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910510", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YZT0", "url": "https://www.orthodb.org/?gene=A0A8M6YZT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017210817", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210817", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YZT0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YZT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JAJ9", "url": "https://www.uniprot.org/uniprotkb/A0AC58JAJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JAJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JAJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDQSKEYPLPNFREKTPSSAQSVRSGSCVSSSVSLKSDWSKDYPPDLREETPSSAKRFKYELPDSGDETHRRRESFTDNLQRIFQNLEKKMIKFLKNELEIFKKILQEENRQEFVKDFSENSSRITEAALDLTLFFLREMKQDQAADTLQGKLFLIDEFKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIDAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTTGVAGIGKSVSVQKFVLDWAERKENQDICFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKPKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKHGLFLQISKTKGVTDFLKTAVDKALESENGHLDLFLRFFLGLSLQSNQQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSRGSLSSADLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKSSTRALLQSCNLTVQCCESLSSALQSSNCVLRQLDLSNNDLQDSGVKLLSDGLKSQHCKLEILRLSGCMVTKEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGQTRITAGPRKYVCFLTLDPNTANTELILSEENREVKSVRENQPYPDHPDRFDVYHQVLCRESVCGRCYWEIDWSGDDGVFISVSYKSIRRKGGGVECKFGFNAQSWSLICSSSRFIFRHNDTDTDLPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCAGFWLYYPGSSVKLS", "length": 1079, "header": "tr|A0A8M6YZT0-1|A0A8M6YZT0_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3-like isoform X1 OS=Danio rerio OX=7955 GN=LOC103910510 PE=4 SV=2 CANONICAL=A0A8M6YZT0-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YZT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT0/entry#A0A8M6YZT0-1", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDQSKEYPLPNFREKTPSSAQSVRSGSCVSSSVSLKSDWSKDYPPDLREETPSSAKRFKYELPDSGDETHRRRESFTDNLQRIFQNLEKKMIKFLKNELEIFKKILQEENRQEFVKDFSENSSRITEAALDLTLFFLREMKQDQAADTLQGKLFLIDEFKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIDAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTTGVAGIGKSVSVQKFVLDWAERKENQDICFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKPKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKHGLFLQISKTKGVTDFLKTAVDKALESENGHLDLFLRFFLGLSLQSNQQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSRGSLSSADLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKSSTRALLQSCNLTVQCCESLSSALQSSNCVLRQLDLSNNDLQDSGVKLLSDGLKSQHCKLEILRLSGCMVTKEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGQTRITAGPRKYVCFLTLDPNTANTELILSEENREVKSVRENQPYPDHPDRFDVYHQVLCRESVCGRCYWEIDWSGDDGVFISVSYKSIRRKGGGVECKFGFNAQSWSLICSSSRFIFRHNDTDTDLPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCAGFWLYYPGSSVKLS", "length": 1079, "header": "tr|A0A8M6YZT0-1|A0A8M6YZT0_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3-like isoform X1 OS=Danio rerio OX=7955 GN=LOC103910510 PE=4 SV=2 CANONICAL=A0A8M6YZT0-1" }, "locus": {} }, { "isoform_ac": "A0AC58JAJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT0/entry#A0AC58JAJ9-1", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDQSKEYPLPNFREKTPSSAQSVRSGSCVSSSVSLKSDWSKDYPPDLREETPSSAKRFKYELPDSGDETHRRRESFTDNLQRIFQNLEKKMIKFLKNELEIFKKILQEENRQEFVKDFSENSSRITEAALDLTLFFLREMKQDQAADTLQGKLFLIDEFKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIDAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTTGVAGIGKSVSVQKFVLDWAERKENQDICFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKPKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKHGLFLQISKTKGVTDFLKTAVDKALESENGHLDLFLRFFLGLSLQSNQQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSRGSLSSADLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKSSTRALLQSCNLTVQCCESLSSALQSSNCVLRQLDLSNNDLQDSGVKLLSDGLKSQHCKLEILRLSGCMVTKEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGQTRITAGPRKYVCFLTLDPNTANTELILSEENREVKSVRENQPYPDHPDRFDVYHQVLCRESVCGRCYWEIDWSGDDDSYSDTMTQTLISQ", "length": 984, "header": "tr|A0AC58JAJ9-1|A0AC58JAJ9_DANRE Computationally mapped isoform of NLR family CARD domain-containing protein 3-like isoform X2 OS=Danio rerio OX=7955 GN=LOC103910510 PE=4 SV=1 CANONICAL=A0A8M6YZT0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103910510", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910510", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZT0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZT0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1013, "end_pos": 1015, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" }, { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 777, "end_pos": 779, "annotation": "n_glycosylation_sequon" }, { "start_pos": 881, "end_pos": 883, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YZT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT0" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 887, "end_pos": 1079, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6YZT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT0" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 268, "end_pos": 402, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1013, "end_pos": 1015 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 364, "end_pos": 366 }, { "start_pos": 685, "end_pos": 687 }, { "start_pos": 777, "end_pos": 779 }, { "start_pos": 881, "end_pos": 883 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YZT8-1", "uniprot_ac": "A0A8M6YZT8", "uniprot_id": "A0A8M6YZT8_DANRE", "mass": { "chemical_mass": 122907.0, "monoisotopic_mass": 122907.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100147926", "type": "recommended", "evidence": [ { "id": "A0A8M6YZT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT8" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 3", "type": "synonym", "evidence": [ { "id": "A0A8M6YZT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT8/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100147926", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT8", "locus": {} } ], "crossref": [ { "id": "A0A8M6YZT8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YZT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100147926", "url": "https://www.ncbi.nlm.nih.gov/gene/100147926", "database": "GeneID", "categories": [ "Genome 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"https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100147926", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100147926", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YZT8", "url": "https://www.orthodb.org/?gene=A0A8M6YZT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017210833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210833", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YZT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YZT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSLSLKSDRSKDDYPPNFSEKTPSSAQSVRSGSCVSSSVSLKSDRSKQGYPPDLREETPSSVRSVEYEAADLGDETHRRHKSFTDNLQSIFQNLESKMIRFLKNELEKFKKILQEENREEFVKEFNENRSIITEAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREINLKEKERQSLKDLITQFFSETKGLNLTRSTRFKVLFILDGLDEYRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAKEIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRTHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNLIFYESDLKDCGIDVYKASVYSGMCTQILKEETGIILGTLYCFLHLSIQEFIAALYQHLILNRDKKRGLFLQISRNKGKIDFLKAAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQSCNLTVLCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKILSDGLKKPECKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGEKRITAGPCKWVCFLTLDPNTAHTLLILSEENREVKRVWGNQPYPDHPDRFDCYPQVLCRESVCGRCYWEIDWSGDAGVDISVSYKSIRRKGDGVECVFGGNAQSWSLFCDSSRFIFSHNNTHTDLPVKALSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFRLYYPGSSVKLS", "length": 1080, "header": "tr|A0A8M6YZT8-1|A0A8M6YZT8_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 OS=Danio rerio OX=7955 GN=LOC100147926 PE=4 SV=2 CANONICAL=A0A8M6YZT8-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YZT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT8/entry#A0A8M6YZT8-1", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSLSLKSDRSKDDYPPNFSEKTPSSAQSVRSGSCVSSSVSLKSDRSKQGYPPDLREETPSSVRSVEYEAADLGDETHRRHKSFTDNLQSIFQNLESKMIRFLKNELEKFKKILQEENREEFVKEFNENRSIITEAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREINLKEKERQSLKDLITQFFSETKGLNLTRSTRFKVLFILDGLDEYRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAKEIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRTHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNLIFYESDLKDCGIDVYKASVYSGMCTQILKEETGIILGTLYCFLHLSIQEFIAALYQHLILNRDKKRGLFLQISRNKGKIDFLKAAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQSCNLTVLCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKILSDGLKKPECKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGEKRITAGPCKWVCFLTLDPNTAHTLLILSEENREVKRVWGNQPYPDHPDRFDCYPQVLCRESVCGRCYWEIDWSGDAGVDISVSYKSIRRKGDGVECVFGGNAQSWSLFCDSSRFIFSHNNTHTDLPVKALSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFRLYYPGSSVKLS", "length": 1080, "header": "tr|A0A8M6YZT8-1|A0A8M6YZT8_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 OS=Danio rerio OX=7955 GN=LOC100147926 PE=4 SV=2 CANONICAL=A0A8M6YZT8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100147926", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100147926", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1014, "end_pos": 1016, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 686, "end_pos": 688, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" }, { "start_pos": 882, "end_pos": 884, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YZT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT8" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 888, "end_pos": 1080, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6YZT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZT8" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 269, "end_pos": 403, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1014, "end_pos": 1016 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 686, "end_pos": 688 }, { "start_pos": 778, "end_pos": 780 }, { "start_pos": 882, "end_pos": 884 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6YZY9-1", "uniprot_ac": "A0A8M6YZY9", "uniprot_id": "A0A8M6YZY9_DANRE", "mass": { "chemical_mass": 120573.0, "monoisotopic_mass": 120573.0 }, "refseq": { "ac": "XP_017212337", "name": "protein NLRC3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212337" }, "gene_names": [ { "name": "si:dkey-222h21.10", "type": "recommended", "evidence": [ { "id": "A0A8M6YZY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZY9" } ] }, { "name": "si:dkey-222h21.10", "type": "synonym", "evidence": [ { "id": "XP_017212337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212337" } ] } ], "protein_names": [ { "name": "Protein NLRC3", "type": "synonym", "evidence": [ { "id": "A0A8M6YZY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZY9/entry#names_and_taxonomy" } ] }, { "name": "protein NLRC3", "type": "synonym", "evidence": [ { "id": "XP_017212337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212337" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017212337", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212337" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YZY9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZY9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-222h21.10", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZY9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081031-22", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081031-22", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YZY9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6YZY9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100331993", "url": "https://www.ncbi.nlm.nih.gov/gene/100331993", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100331993", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331993", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YZY9", "url": "https://www.orthodb.org/?gene=A0A8M6YZY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017212337", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212337", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YZY9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YZY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081031-22", "url": "https://zfin.org/ZDB-GENE-081031-22", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": 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"MSAPSSHDHPSTCDENMTSDPRVTLRKTPRLESSGPSGVSVKSDWSMERPPALSNQPVTSDPRVNQRKTPRLESPELSGVSVKSDWSKERPPAFSDEPVTSDPRVNQRKTPRLESPELSGVSVKSDWSIERPPAFSNEPVTSDPRRCDIHERCVNITQSNIGSQTLKTRDLQRVKDQLKASMKNKYELLSEGIKVKENQTHLNRIYTQLYIIEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEKCKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRINEKHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGIDICEASVCTGICTEIFKEESVILLTKVYSFIHLSVQEFLAAFYVFYVHVSSTTEASFDSLENLHKRIIDKAIESENGHLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHLRIKQGFLKYACFLTLDPNTAHNQLQVSDGNRKAVHMKDPQPYPDHPERFELQEQVLCRETLTGRCYWESKWSGSGYVAVAYKAIDRKGGLESWFGLNERSWSIYCSNINYTAWHNNEGTDIIAPSSRNNRVGVYVDVPSGSMSFYSVSDTHTLTHLHTFNTTFTEDIYAGFRIYPKSSVSLCQI", 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"url": "https://www.uniprot.org/uniprotkb/A0A8M6YZY9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1034, "end_pos": 1036, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 731, "end_pos": 733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 746, "end_pos": 748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 756, "end_pos": 758, "annotation": "n_glycosylation_sequon" }, { "start_pos": 983, "end_pos": 985, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6YZY9", "database": "UniProtKB", 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z010-1", "uniprot_ac": "A0A8M6Z010", "uniprot_id": "A0A8M6Z010_DANRE", "mass": { "chemical_mass": 120625.0, "monoisotopic_mass": 120625.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100536766", "type": "recommended", "evidence": [ { "id": "A0A8M6Z010", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z010" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z010", "database": "UniProtKB", "url": 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PYD domains-containing protein 3 isoform X2 OS=Danio rerio OX=7955 GN=LOC100536766 PE=4 SV=1 CANONICAL=A0A8M6Z010-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100536766", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536766", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z010", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z010" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z010", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z010" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1016, "end_pos": 1018, "annotation": "n_glycosylation_sequon" }, { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 574, "end_pos": 576, "annotation": "n_glycosylation_sequon" }, { "start_pos": 641, "end_pos": 643, "annotation": "n_glycosylation_sequon" }, { "start_pos": 646, "end_pos": 648, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" }, { "start_pos": 758, "end_pos": 760, "annotation": "n_glycosylation_sequon" }, { "start_pos": 864, "end_pos": 866, "annotation": "n_glycosylation_sequon" }, { "start_pos": 996, "end_pos": 998, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z037-1", "uniprot_ac": "A0A8M6Z037", "uniprot_id": "A0A8M6Z037_DANRE", "mass": { "chemical_mass": 22985.0, "monoisotopic_mass": 22985.0 }, "refseq": { "ac": "XP_017213077", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213077" }, "gene_names": [ { "name": "LOC101882928", "type": "recommended", "evidence": [ { "id": "A0A8M6Z037", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z037" } ] }, { "name": "LOC101882928", "type": "synonym", "evidence": [ { "id": "XP_017213077", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213077" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M6Z037", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z037/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017213077", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213077" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213077", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213077" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z037", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z037" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101882928", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z037", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z037", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z037", "database": "AlphaFoldDB", "categories": [] }, { "id": "101882928", "url": "https://www.ncbi.nlm.nih.gov/gene/101882928", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:101882928", "url": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z042-1", "uniprot_ac": "A0A8M6Z042", "uniprot_id": "A0A8M6Z042_DANRE", "mass": { "chemical_mass": 153027.0, "monoisotopic_mass": 153027.0 }, "refseq": { "ac": "XP_017212451", "name": "protein mono-ADP-ribosyltransferase PARP14-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212451" }, "gene_names": [ { "name": "parp14rs2.1", "type": "recommended", "evidence": [ { "id": "A0A8M6Z042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z042" } ] }, { "name": "parp14rs2.1", "type": "synonym", "evidence": [ { "id": "XP_017212451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212451" } ] } ], "protein_names": [ { "name": "Poly [ADP-ribose] polymerase", "type": "recommended", "evidence": [ { "id": "A0A8M6Z042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z042/entry#names_and_taxonomy" } ] }, { "name": "2.4.2.-", "type": "synonym", "evidence": [ { "id": "A0A8M6Z042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z042/entry#names_and_taxonomy" } ] }, { "name": "PARP", "type": "synonym", "evidence": [ { "id": "A0A8M6Z042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z042/entry#names_and_taxonomy" } ] }, { "name": "protein mono-ADP-ribosyltransferase PARP14-like", "type": "synonym", "evidence": [ { "id": "XP_017212451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212451" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017212451.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017212451", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212451" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z042", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z042" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "parp14rs2.1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z042", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z042", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z042", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01439", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01439", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101885419", "url": 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"id": "dre:101885419", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885419", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z042", "url": "https://www.orthodb.org/?gene=A0A8M6Z042", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14453:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14453:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23222", "url": 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"MVFIKEESEDVKIEETFTVKQEDLQEQTDLIEKNERKEEEHHVKIEEKTHLQTDGILKRGDKNSFTCTQCGKSYGSKDYLKIHMRIHTGEKLFTCPQCGKSFGRKRELKIHRRIHTGEKPYTCTRCGKSFSQSSNLNQHMRIHTGEKPFTCTQCGKSFNRSSSLNEHMMIHTGEKPFTCTQCGKSFGRNFDLKIHMMIHTGENPFRCTHCGKSFSQSSYLNQHMRIHTRENPFTCTQCGKSFHRSSSLNNHKTIHTREKPFTCTQCGKTFNNSSHLYEHMRIHTGEKPFTCTQCGKNFNQSSNLNRHMRIHTREKPFTCTQCGKNFICSSSLNLHIMSHTGEKLALKQRSQWTFFPMDFHSYARECVRPETKFVCQVSQFTALQSSSLVNSDLQNRIT", "length": 398, "header": "tr|A0A8M6Z043-1|A0A8M6Z043_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC103910729 PE=4 SV=2 CANONICAL=A0A8M6Z043-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z043-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z043/entry#A0A8M6Z043-1", "sequence": { "sequence": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z047-1", "uniprot_ac": "A0A8M6Z047", "uniprot_id": "A0A8M6Z047_DANRE", "mass": { "chemical_mass": 129547.0, "monoisotopic_mass": 129547.0 }, "refseq": { "ac": "XP_017211145", "name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211145" }, "gene_names": [ { "name": "si:dkey-165e24.1", "type": "recommended", "evidence": [ { "id": "A0A8M6Z047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z047" } ] }, { "name": "si:dkey-165e24.1", "type": "synonym", "evidence": [ { "id": "XP_017211145", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211145" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017211145", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211145" }, { "id": "A0A8M6Z047", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z047/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017211145.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211145", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211145" } ] } ], "disease": [ { "disease_id": "DOID:0050854", "recommended_name": { "id": "DOID:0050854", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "Muckle-Wells syndrome", "description": "A syndrome characterized by episodic skin rash, arthralgias, and fever associated with late-onset sensorineural deafness and renal amyloidosis that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q44." }, "synonyms": [ { "id": "DOID:0050854", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "MWS", "description": "" }, { "id": "DOID:0050854", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "neutrophilic urticaria", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle-Wells syndrome", "description": "An intermediate form of cryopyrin-associated periodic syndrome (CAPS) and is characterized by recurrent fever (with malaise and chills), recurrent urticaria-like skin rash, sensorineural deafness, general signs of inflammation (eye redness, headaches, arthralgia/myalgia) and potentially life-threatening secondary amyloidosis (AA type)." }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle-Wells syndrome", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "neutrophilic urticaria", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "MWS", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle Wells syndrome", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "urticaria, deafness and amyloidosis", "description": "" }, { "id": "MIM:191900", "resource": "MIM", "url": "https://www.omim.org/entry/191900", "name": "Muckle-Wells syndrome", "description": "Muckle-Wells syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050854", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050854" } ] }, { "disease_id": "DOID:0080208", "recommended_name": { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol." }, "synonyms": [ { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "nonalcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "non-alcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "NAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-related steatotic liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MASLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic-associated fatty liver disease", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "NAFLD2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "fatty liver disease, nonalcoholic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "liver disease, alcoholic, susceptibility to, 1", "description": "" }, { "id": "MIM:613282", "resource": "MIM", "url": "https://www.omim.org/entry/613282", "name": "Non-alcoholic fatty liver disease 1", "description": "Non-alcoholic fatty liver disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ] }, { "disease_id": "DOID:0080270", "recommended_name": { "id": "DOID:0080270", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080270", "name": "autosomal dominant nonsyndromic deafness 34", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q44." }, "synonyms": [ { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "hearing loss, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "DFNA34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "autosomal dominant nonsyndromic deafness 34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "deafness, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MIM:617772", "resource": "MIM", "url": "https://www.omim.org/entry/617772", "name": "Deafness, autosomal dominant, 34, with or without inflammation", "description": "Deafness, autosomal dominant, 34, with or without inflammation" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080270" } ] }, { "disease_id": "DOID:0090029", "recommended_name": { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "CINCA Syndrome", "description": "An autoimmune disease characterized by neonatal onset of cutaneous symptoms, chronic meningitis, and joint manifestations with recurrent fever and inflammation that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q." }, "synonyms": [ { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "IOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "NOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic infantile neurological cutaneous articular syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "Chronic Infantile Neurological, Cutaneous, and Articular (CINCA) syndrome is characterized by skin rash, joint involvement, chronic meningitis with granulocytes and, in some cases, sensorineural hearing loss and ocular signs." }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA/NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Neonatal-Onset Multisystem Inflammatory Disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic infantile neurological cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal onset multisystem inflammatory disease", "description": "" }, { "id": "MIM:607115", "resource": "MIM", "url": "https://www.omim.org/entry/607115", "name": "Chronic infantile neurologic cutaneous and articular syndrome", "description": "Chronic infantile neurologic cutaneous and articular syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090029", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090029" } ] }, { "disease_id": "DOID:0090062", "recommended_name": { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "familial cold autoinflammatory syndrome 1", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP gene on chromosome 1q44." }, "synonyms": [ { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "FCAS1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "Any familial cold autoinflammatory syndrome in which the cause of the disease is a mutation in the NLRP3 gene." }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "NLRP3 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP3", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome type 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold inflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "FCAS1", "description": "" }, { "id": "MIM:120100", "resource": "MIM", "url": "https://www.omim.org/entry/120100", "name": "Familial cold autoinflammatory syndrome 1", "description": "Familial cold autoinflammatory syndrome 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090062", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090062" } ] }, { "disease_id": "DOID:0090063", "recommended_name": { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "familial cold autoinflammatory syndrome 2", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP12 gene on chromosome 19q13." }, "synonyms": [ { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "An autoinflammatory disease caused by mutations in the NLRP12 gene. It is characterized by periodic fevers beginning in the first year of life that are triggered by cold exposure. Episodes occur more than once per month." }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NALP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NAPS12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome type 2", "description": "" }, { "id": "MIM:611762", "resource": "MIM", "url": "https://www.omim.org/entry/611762", "name": "Familial cold autoinflammatory syndrome 2", "description": "Familial cold autoinflammatory syndrome 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090063" } ] }, { "disease_id": "DOID:12351", "recommended_name": { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "alcoholic hepatitis", "description": "" }, "synonyms": [ { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic hepatitis", "description": "" }, { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic liver disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12351" } ] }, { "disease_id": "DOID:1555", "recommended_name": { "id": "DOID:1555", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1555", "name": "urticaria", "description": "A skin disease characterized by skin rash notable for pale red, raised and itchy bumps, located_in the upper dermis." }, "synonyms": [], "unlinked_id_list": [ "DOID:0060220" ], "evidence": [ { "id": "1555", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1555" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:9452", "recommended_name": { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes." }, "synonyms": [ { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Fatty change of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Steatosis of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "alcoholic fatty liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic lipidosis", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "SLD", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "fatty liver disease", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "fatal neonatal hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z047", "url": 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101884333", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884333", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z047", "url": "https://www.orthodb.org/?gene=A0A8M6Z047", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017211145", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211145", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z047", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z047", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z047-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z047-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JAI5", "url": "https://www.uniprot.org/uniprotkb/A0AC58JAI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JAI5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JAI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081103-19", "url": "https://zfin.org/ZDB-GENE-081103-19", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAEERVKDSLSEKHRVRSGSCVSSSVSLKSDCSKEDPPKFSEKTPSSAQSVRSGLCVSSFVSLKSDCSKEDPPKFSEKTPSSAQSDEDELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNELEKFKQILQEENRQEFVKDYNENRSRITEAALDLTLFFLREMKQDHAADTLQDELLFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAVSRRHQSLETQVEFKHLFKAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQLFPETKGLNLTRSTQFKVLFILDGLDECRLPPNFAGNEMCCDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILNLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSQGKLAFQQLERNNVIFYESDLNDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEGIIAYIKQKLEGNLSPERSINLFYCLSELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELWKFQRSDECLIRLSAIIKNSKRALLQSCNLTVQSCKSLSSILQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLATCNLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSEHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDTLNLDHVGDMRITAGPRKYVCFLTLDPNTANTQLKLSKENRKVKHVREDLRIMRKDRRYPYHPDRFDPVFQVLCRESVCGRCYWEIDWSGDHGVFISVSYKSIRRKRGDACEFGCNAQSWSLLCLSSRFTFRHNNTHTHVPVKPLSRRIGVFVDHSAGTLIFYNIYKDTMSLIHSVQTTFTEPLCPGFGFYSGSSVKLS", "length": 1137, "header": "tr|A0A8M6Z047-1|A0A8M6Z047_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3-like isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-165e24.1 PE=4 SV=2 CANONICAL=A0A8M6Z047-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z047-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z047/entry#A0A8M6Z047-1", "sequence": { "sequence": "MAEERVKDSLSEKHRVRSGSCVSSSVSLKSDCSKEDPPKFSEKTPSSAQSVRSGLCVSSFVSLKSDCSKEDPPKFSEKTPSSAQSDEDELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNELEKFKQILQEENRQEFVKDYNENRSRITEAALDLTLFFLREMKQDHAADTLQDELLFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAVSRRHQSLETQVEFKHLFKAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQLFPETKGLNLTRSTQFKVLFILDGLDECRLPPNFAGNEMCCDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILNLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSQGKLAFQQLERNNVIFYESDLNDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEGIIAYIKQKLEGNLSPERSINLFYCLSELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELWKFQRSDECLIRLSAIIKNSKRALLQSCNLTVQSCKSLSSILQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLATCNLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSEHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDTLNLDHVGDMRITAGPRKYVCFLTLDPNTANTQLKLSKENRKVKHVREDLRIMRKDRRYPYHPDRFDPVFQVLCRESVCGRCYWEIDWSGDHGVFISVSYKSIRRKRGDACEFGCNAQSWSLLCLSSRFTFRHNNTHTHVPVKPLSRRIGVFVDHSAGTLIFYNIYKDTMSLIHSVQTTFTEPLCPGFGFYSGSSVKLS", "length": 1137, "header": "tr|A0A8M6Z047-1|A0A8M6Z047_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3-like isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-165e24.1 PE=4 SV=2 CANONICAL=A0A8M6Z047-1" }, "locus": {} }, { "isoform_ac": "A0AC58JAI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z047/entry#A0AC58JAI5-1", "sequence": { "sequence": "MAEERVKDSLSEKHRVRSGSCVSSSVSLKSDCSKEDPPKFSEKTPSSAQSVRSGLCVSSFVSLKSDCSKEDPPKFSEKTPSSAQSDEDELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNELEKFKQILQEENRQEFVKDYNENRSRITEAALDLTLFFLREMKQDHAADTLQDELLFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAVSRRHQSLETQVEFKHLFKAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQLFPETKGLNLTRSTQFKVLFILDGLDECRLPPNFAGNEMCCDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILNLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSQGKLAFQQLERNNVIFYESDLNDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEGIIAYIKQKLEGNLSPERSINLFYCLSELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELWKFQRSDECLIRLSAIIKNSKRALLQSCNLTVQSCKSLSSILQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLATCNLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSEHCKLDTLSLDHVGDMRITAGPRKYVCFLTLDPNTANTQLKLSKENRKVKHVREDLRIMRKDRRYPYHPDRFDPVFQVLCRESVCGRCYWEIDWSGDHGVFISVSYKSIRRKRGDACEFGCNAQSWSLLCLSSRFTFRHNNTHTHVPVKPLSRRIGVFVDHSAGTLIFYNIYKDTMSLIHSVQTTFTEPLCPGFGFYSGSSVKLS", "length": 1079, "header": "tr|A0AC58JAI5-1|A0AC58JAI5_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3-like isoform X2 OS=Danio rerio OX=7955 GN=si:dkey-165e24.1 PE=4 SV=1 CANONICAL=A0A8M6Z047-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "A0A8M6Z047", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M6Z047" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0A8M6Z047", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M6Z047" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:101884333", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884333", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JW23-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPATAKDALHRLSTYLEELEAGELKKFKLYLGIAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGEDLVRVTPSNGLCSLESQSTCLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGPWCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTSRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFTAMYCALHGREAVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAEDGPPEPPGAQTQSTHSQERNILPDIYSAYLSATICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIANRNLIRLDLSGNSIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSNNSHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVNTCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGISQTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFGMDLNKVTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1PS14-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:dkey-222h21.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNMLQRIKNQHKTSLKNKYERLFEGIEVKETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPENLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGIDVSDASVYSGICTEILKEESVIQQRKVYSFIHLSFQEFLAAFHVFYHHITCSTEASLDSLHDLQKRIINKSTESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKRSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELKLQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITPGLRKYACVLTLDPNTAHTHLVLSEKNRQARNVTDPQPYPDHPDRFKNNEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYSCDTIYTVWHNNKSADIIAPSACTNRVGVYVDVPSGSLSFYSVTDTHTLTLIHTFNTTFTEELYTGFGIYPEASVSLCQI", "length": 892 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3ANC0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch73-168d20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSRKRRSSSPESSCVSIKSDASMDNPPTLRLGESPAKHRRSSSLGSSCVSMKSDASMDNPPTLRLGESPAKHRRSSSPESSCVSMKSDASMDNPPTLRLGESPAKHSDNQKRSQSNKGQKQLDAIFKDLEETNIDEMRKVLRRFKMLLSPDYSVRDEEEEEGQRQINEAFLKITLHALQKMNQTDLASKLQTKLISVSQQQLKSRLKQRFERFTEGVSNRGNTKLLNDIYTEVYITEGGAGNIDDEHEVRQIETSSSRFPEIPIRCCDIFKSLLGQDKAIRTVLTKGVAGIGKTASVQKFILDWAEGKANQDVHFIFPLPFRDLNLIKEKRMSLMELLCCFCPELKPIDYNNFKTVFIYDGLDEWRLPLDFRNNEILWDMNKVASVDALLTNLLQGNLLPSAVHWITTRPAAACQIPAEFIDRVTEVRGFKDLQRAEYFWKRIKDQNLANKIITHIQSSRSLHIMCRIPVFCWISATVLEKIFGEANSADIPKTLTQMFIHLLIVQTNLKTQKYDRECDVNLEKARKSILSLAKLAFEQLEKGNLIFYEEDLKQCGIDVREASVCSGVCTQIFREEFGLQLQKVFSFVHLSVQEFLAALFKFLSFAEENNKSSMTQFMKNEVDRALQSPNGHLDLFLRFLLGLSLDSNQTLLQGLFTPLDTSHSRDETIEYIKSKIRENPSPERSINLFYCLNELNDHSLVQEVQTYLTSTRSHRLSGVKLSPALWSALVFVLLNSTKDLDEFELRQYDFTEECLLRLLPVVKASRKADLKGGNLTDQICSALASALSSSSCCLRELDLSENRLQLSGIRLFSAGLKSPNCKLEILKLSNCSIREEGCASLVSALLSNPSHLRELNLNSNQPGYSTVKLLSDLLENPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLNGSNIREKDCAAFISSLLSNPFHLRELSLSWNKPGDSGVKLLSDLLKDSRCKLEKLELECCSIIEEGCAALALALVSNPSHLRELNLNNNEPGDLGVNLLSFLLKNPQCKLEKLELEYCCIGAKSCASLASAFVSNPSHLRELNLNWNTPEYPAVKLLSDYLKDPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLEYCCIGEEGCAALVSGLKSNPSHLRELNLNRNEPGNLGAKMLSDLLKDPLFELEKLELDDCSIENNGFADLVSGLKSNPSNIRELNLNSNKFIFSGLNLLCDLLRDQQCKLRKLQLECCNIDEEGCAALALALISNPSHLRELNLNYNNPGGLGVKLLSVLLKNPHCKLEKLELSHCSISENYLAALNSALSSNPAHLRELNLNYNENTRQ", "length": 1388 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQ59-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKIFQNLTAESGKGIRDYVVQIRFCFIMDDTQISRDENVSPGCSSVHQKRSDPEPSCVSMRSDWSMDPPISFKSKDTPPDFSSVHQKSTESEPSCVSMRSDDESVDQPLHVRSGDTETDLSHEALNTFRSDLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIIPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLMNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHLLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDGFEEIKKPSLWSKVKDLLYLNSSQLVSLSELHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQIILQRLMILKSRSIQINKTVEYIKMKIRTIDSPEKFINLFHCLNELGDHSLVEEIQQYLKSGRINRAKLSESQWSAVAFVLLTSEKKLEEFHINEFVGETEKIFIFMKLLPVIRECRSVQLNNCGLTDEGCAALASALRSNPEHLRELNLSGNRLGDSVTLLSALLEDPRCNLEILWLSYCGLTDEGCAALASALRLNPEHLRELNLSHNNISKSTVKLLSDLKHNPHNKLETLYI", "length": 837 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B0M3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "si:dkey-7i4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESDEQHNDTLVQMGSSGNSGINADLRAEKEATVIAPLLNGNNITGPVTFNYCSNSAENEPQKYPKTADKHTEKQDDLKLQKILETHRTYMKKKVDCILDCTKENAEHFKAFYTELFIAEGDMQDVNQEHEILKIDDAFKKKKASLRSIRCKDIFAELKAKSEKNTVLTKGIAGIGKTVSVRKFILDWAEGQTNHDIHCVFLLPFREINLMTNEDFNLHEFLLKFYPELKELETSVLFQQCNLAFIFDGLDESRLPLNFKSRTLNNVEERSSVDMLFTSLVKGNLLPSALVWVTSRPAAANQIPPRYVGLFTEVQGFTDQQKEKYFRNRIADETQASKIISHIKTSRSLYIMCHIPVFCWITATVLQDILQRNIESIGTTLTEMYIHFLLIQMNMKSQKYDPEEEREYAKLLEANREVILKLAKLAFEQLKKENVVFYEQDLKDCGIDVNVEFTGMIAEIFKVEHGLHEAKVFYFVHLSVQEFLAAVYVFFCFLNRNTHELTFFFESSQNTPRELQFLFKKTFRKVKFHDLIKRATDKAMRSKRGHLDLFLRFLLGISLESSQNLLKGLFSHVIDTTRSIKKISPHFKHLQNKNISCDCSVNLFFCLLELKDHSLYEEIQRSLNSDRRPSKELSSSMCTVLTYIVLMSEKELDELNPKRFTSSQENYRKLVPAVRCCRKALFNGCGLDEMSFQTISSALQSSDSYLTELELSNNHLQDSGVKLLSDGLKSSHCQLNILRLCGCGLTDQSCESLSSALQSSNSVLRELDMSNNMLKDSGVKLLAVALKSLNCKLERLRFSMCNLTAESCESLSSVVELSNSVLRELDLSNNDLQDSGVKLLSDGLKRNCRLEILRLSGCMVTEVGCGFLSSALSSTTSTLRELDLSYNHPGDSGEKLLSDAHNQPNCRLCVDHGGEFRLTTGLHKYARFFTLDPNTANARLILSEENRKVTCVRKKQPYPDHPDRFEGYLQVLCRESVCGRSYWEIEWTGVVFISVSYSSIGRMGSDKECWFGFSNQSWSLFCSSDRCSFTHSSTEIDLPVKHTSSRIGVYVDHSAGTLSFYSVSDTVSLIHSVQTTFTQPLHPGFYISLGSSVKLC", "length": 1096 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YSM0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch211-181d7.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSHKQTLKYFSPVCSSVQQERSDSAEPSSVSVKSHWSIDPPPQMTERRDSLSLALQERSDSPEPSHVSMKSDWSIDPPPQMKEENRSLVQQERSPKSSCVSMKRDWSIDPPPQMNDEDGQKRLSLVQQERSDSAEPSLVSMKSDWSIDPPPQMKDGDRQKSLSLVQQERSDSPEPSHVTMKSNWSIDPPPQMTDRRDSLRQIPRPRPGAEEPISKKMKYDESVIKSQECMENPSLIFSHEVNTFRVNLLKKFQCLYEGMVTQDNPALLNEIYTELYITESESGEISNEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPETKEIDIFSDKYKILFIFDGLDECRLLLNFKSNEILQHVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLMAQINTKDMKYTGKKDKDMIFKLGKLAYEQLERGNVIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFIHLSVQEHLAALYVHLLFTNHNRNVFEQMTKKTSKTLDILDCFHSNSPENVLLSELHQKAVDEALQSKNGHLDLFLRFLLGLSLESNQILLQELMIKFRSSSDSSEKTVEYIKKRINNICLPEKSINLFYCLNELGDHSLVKEIQQYMDYGTLAETKISCGQWSALVFILLTVEQAMDVFELNKFIGLKKSSDEVLRKLLPVIKKSRSAIMDDCNITAEGCAYLASALGSNPSYLRELDLSANKLQDSGIKKLSKGLQDSHCKLEKLNLYHCGVTNEGCAALASALKSNPEHLRDLNLSENKIGNLGLTCLSEILKNSLCKLEILRLCQCGITDCTDLASALISNPEHLRELELSLNKIGDSGVTALCAAFEDPRFKLEKLGLSGCGLTDEGCAALTSALRSNHEHLRDLDLSGNKVDKEVKGSILQRILEKLNNIQILSV", "length": 1068 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YU37-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch73-24k9.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDNQTFSDAPVCSNESNPEFEPSCVSMKSDQSMDPPMKFKEGHTSADLSDRLNPPGSSCVSMKSDWSMDRPIQFKEEHSSADLSNKSNPGEPSCVSSKSDQSMGPPINVMEEHSAADLRLDPHLKQNGLRSNLLRKFQCLYEGTAMQGDPTLLNEIYTELYITESDSGEINNKHELRQIETRSRRSATEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEEKENQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEQFKVLFIFDGLDECRVSLDFKCDVKLHDVSESASVDVLLTNLIMGNLLPSALIWITSRPAAADLIPSEFVHRVTEIRGFNDPQKEEYFRKRIRDQFLADIIIINLKSSRSLHIMCHIPVFCWISATVLEKIFSQAQSGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEVRDEDMILKLGKLAFEQLVKGNLIFYEEDLRECGLDVTEASVYSGLCTQIFREEFGFYQGKVFCFVHLSIQEHLAALYAHHSLTNKNRNVFKQTKPSLLSKVLNQKKHDSLSVLHQRAVKEASQSKNGHLDLFLRFLLGLSLESSGTLLRELLTQTGSCSYNKEETVQYIKQKIRENRSPERSINLFHCLNELGEDSLMQEIQDYLSSGEIKETKLSSSQWSALVYVLLTSEKKMDFFDLSKFIGPQLRADVVLQKLLPVVKESRSVRLGDCKVTDKVCAALASALRLNSSHLTQLDLIGNKLGDSGVKLLSDGLKDPHCKLKNLMMRDCGVTDEGCAALASALRSNSTHLTELNLNENNLGDAGVKRLSDGLKGPHCKLEILRLWRCGVRDEGCAALASALSSNSTHLKELELSDNKLGDSGVKLLSDALKDPHCKLEKLRLNGCGVREQGCVSLALALRFNPSSHLTELDLTSNELGKSGVKLLSDLRDDPRYKLRHLACDMFGRIIVSSGGGRLDELLPTTSTET", "length": 978 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1F5-1", "protein_name": "Protein NLRC3", "gene_name": "si:dkey-23k10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METEGPDSPEPSCVSLRSDHSKAHHVLFKDEDPFEYSSGQTGRSSPTPSHVSLASNMSINQPLEFKSCSNTLLLKEIQEAIQSVLRIRFQCLHEGLSKHSVLIPLNDIYTELYITEGEGGELNNEHEIRWIETACRRALTEDRPVNLNDIFKPLHGQDRPIRTVLTKGVAGIGKTVSVQKFIIDWAEGEANQDIWFIFPLPFRELNLLKDQSFSLKGLLQYFMNIELDISLHEGKIMFIFDGLDECRLPLDFHNNVKLCDVTESASVDVLLTNIIRGNLLPSSLIWITSRPAAADVVPSKCIHRVTEVRGFSDPQKEEYIRKKVSDQTLSDRIISHLKSSRSLYIMCHIPVFCWISATVLKKMLSEAESAEIPNTLTQMYTQFLMLQLRIKNEKAYDKKSSDIDIVLKLGELAFQQLEKLNLIFYKEDLREYGIDEQEASVYSGLFREESGMFQGKVYSFVHLSVQEHLAALYVYLYFVNENINKLNQPNFLTSILKCVPTVFDVYQTAVKKALQSTSGHLDLFLRFLLGFSLESNQNLLGDLQVQTESSSDSREQIVGFIKEKIKESPPPEKMINLFHCLNELNDHSLVEEIQDFLQSESRINMKLTASQWSAMVFVLLTSGQKLDVFDLNKYIGTYILPDESLQRLQPVLAASRTAKLCEHNLTKRGYSVLVSVLTSKTSCLRELNLTRSAVNDSGLKLLCSGLENPQCKLETLRLEFCGVSDKGCDFLASALRSNPSHLKALDLSGNTLNFTGLKNLLAEFQKPHCKLQRLCLRLCGLTDVGCDALASVLRSDPSHLTELNLSGNKLGDLGMKLLAGGLQNPHCKLQILRLGDCSITHEGCAALASALRSNPSHLRELDLSGNKLNNAGVQILSGELENPDCNLEILRLENCDVGEEGCAALAEALKSNPLTLKELDLCWNKLGNSGVQRLCTSLENPNCTLGVLRLTGCNISENGCAALASVLRSNPSYLRDLDLSHNDLRSSGVRLLSSALEKPDCKLEILRLEYCKITDDGCAVLASALKSNPSHLRELYLYMNSFNLTASGRQLLSKIKDDPHYKLQTLHYESHFFC", "length": 1074 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z5L8-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch211-207e19.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKDFNENRSRITDAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTDHEIRQIEAASRRHQSLEIQVECKHLFEAAEQHEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETEGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVDKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKKQGWFFIQISKNKGMIDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKGEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSADLSPAQWSALVFVLLTSEEELEVFELQKFQRSDECLIRLSAVIKTSKRALLQGCYLTVRSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLQFCNLTVQCCESLSSALQSSNCVLRELDLSINDLQDSGVKKLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKYVCFLTLDPNTAHTELILSEENREVKSVRENQPYPDHPDRFDYYHQVLCRESVCGRCYWEIDWSGDGVVCISVSYKSIRRKGGGDECVFGYNAQSWSLRCDSSRFKFWHNNTHTDLPVEALSSRIGVFVDHSAGILIFYNIYRDTMSLIHSVQTTFTEPLCAGFRVYYPGSSVKLS", "length": 995 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PCI8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTQTTIEKDYSPRFSLVHQKRSEPSCVSIRRDQSVAHPIDFKSEDTQTHLSSVHQERLDPEPSCVSIRSDRSVAHPIDFKSKNTHLSSVHQERSEPEPSCVSIRSDRSVAHPIDFKSEDTQTHLSTFHQKRKEADPSCVSMRSDTFMNQPINIKIGETQNDLKQNLLNTFRSNLLKKFECLYEGTAVQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQNKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSEKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCLNNNRNEFEQISKQSLWSKVRDHFHFNSSKLVSISKLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQGLMKLKIRSIQNNETVEYIKKKIRKINFPEKFINLFHCLNELGDHSLVEEIQQFLKSGGMNEAKLSSSQWSAVVFVLLTSEKKLEKFDINEFAARNNNTEQLFIFKKLQPVIRQCRSVQLSYCGLTDEGCAALASALRSNPEHLRDLYLSGNKLGDSVSLLSGVLEDPHCKLETLWLSDCGLTSKDSAALASALRSNPEHLRVLDLSWNRLGDSVTLLSAVLEDPHCKLETLLLRDCGLTDEGCAALASALRSNPEHLKHLDLSWSNLGDSVTLLSAVLEDPRCKLEKLGLSNCGLAEEGCAALASALRSNPEHLRGLNLSVNNLGDSVTLLSAVLEDPRCKLEKIKLSYCGLTDEGCAALASALRSNPEHLRDLDLSTNNLGDSVTLLSAILEDPHCKLEKLELKNCGLTDEGCAVLASALRSNPEHLRDLNLSWNNLSNSTKKLLSDLKDDPHNKLETLHTSLSV", "length": 1115 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PLT8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "nlrc8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSMNHPKHFKSGETQNDLGSAHQKRSDPEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQKRSDPEPSCVSMKSDWSMDPPMQFKSKDTPPDLSSVHQERSEPEPSCMSMNSDLPLDPPIRYKSGETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQSLWSKTKFMFKTVALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLKLKRRSIKNNKTVEYIKKKIRTIDSPEKSINLFHCLNELGDHSLVEEIQQYLKSGGINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAENNKTEKLVIFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTLLSAVLEDPHCKLEKLWLSYCGVTDEGCAALVSALRSNPEHLRELNLSGNNLGDSVTLLSAVLEDPHCKLEKLRLYYCGLTDEGCAALASALRSNPEHLRDLDLSWNKLGDSVTLLSAVLEDPRCKLEKLELYNCGLTDEGCAALASALRSNPEHLRDLNLSGNKLGDSVTLLSAVLEDPRCKLEKLWLSDCGLTDEGCAALASALRSNPEHLTELDLSWNNLSKSTVRLFSDLKDNPHNKLKTLHI", "length": 1017 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPT2-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSKRKREDEDAASEISSASPGSSCVSVKSDQSMKKNLPDFSDASVTSDLSISKTINQRSASPEFSVLSMTSNRSIGQPENFSDEPVTFDSVLSDALDKPDYEKLHRIKDQHKTSMKNKYERLFEGLKLDETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHRASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFHVFYYHVNTTMDGLRNFASVENLIKGAVDKAIESENGHLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLFREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCGIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTRQKLNWDHGGHFRITPGLRKYACFLTLDPNTAHNQLILSEDKRKVTHVKDPQQYTDYPEKFVHQEQVLCKETLTGRCYWEVEWSGEGTDIAVAYKGIRRKAGSDCWFGYSEKSWSLFYTGNGFNVWHNNKSQIIPAPSPLSNRVGVYLDTESGSLSFYSVSDTHTLTHLHTFNTTFTEPLYAGFRVFDSSLSLCNI", "length": 993 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PSD3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEEQGKMSLSEKHSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKPMSAKSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKQTSAKSVISDSCVSGSVFVKSDCSKDGDLPNFSEETPSSGKSFEHKTSDSDFQTHRKHKGFQDGLLGIFQDLENQIMNYLKHELEKFKKILQKENIIDFVKDFNENRCSIKEAALDLTLYFLREMKQEESADTLEDELIFIHQLKCGLQKKYQCVFEGIAQQGDSRLLKNIYTDLYITQGGSEQVNTEHEVRQIEVASRRHEAQELQVECRHLFEASEQDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQEISFIFPLPFREMNLKEKETLSLMELITQFFPETKGLNLTRRNRFKVLFILDGLDECRLPLNFAGNETCCDVSSPASLDVLLTNLIKGNLLPSALIWITSRPAAASKIPPDCIDRLTEIRGFNDAQKEEYFRKRLTDENQAKEIIDHVKQSKSLFIMCHIPVFCWISATVLQNILQEKRNNDVKHNQADDASKTLQESNTEDTPKTLTQMYTHFLRFQIQQSRRKYNGEYTPDVSWDKDAILSLGKLAFHHLLNNNLIFYDTDLEACGIDVYKASVYSGMCTQIFKEETGIILGTMYCFVHLTLQEFIAALYAHLILDTNKKSVFDQDSKKINESMIDLLKTAVDKALESDNGHLDLFLRFLLGLSLQSNRRILRGLLTPQDQDDQSTEKILQYIKQKFDANLSPERSINLFYCLNELNEQTLVKEIQTHLSKGSLSSADFSSAHWSALAFVLLTSDEEMEEFELQKFHKSDECLIRLSAVIKTCKRALLNDCNLTDRSCSALATVLESDTSLKELNMSNNNLQDSGVKLLCTGLKDMKCELEILRLSDCNITEEGYKALASALRSNPSHLLELDLRGNDPGESGVKELDDLLQDPNCTLKTLRFLSPSAEESCQFVNGVVGKNPLLLKTLNLNDFRSTRNHPFIYEIEDTQVNHLAALLQDKHCRVNMLILGGCSFTDDQWESLTSALKLNPSHLRELILMWNGPGESGVKILSDFLIEPQLKLEKLCLCYCSITEERCEILTSALKSNPSHLRELNLSQNIPGDSGMKNLSDLLMNPQSKLEKLQLCKCSITEEQCVILTSALKSNPSHLRDLNLSLNNLGDSGVKTLSDLLMKPHLKMEKLWLCKCSITEEQCVILASALKSNPSHLRELSLSENNLGDSGVKNLSDLLMKPQFKLEKLHLSHCSITEEQCEILTSALKSNPSHLRELDISKNQIRNTGVNLLCDVLNNSDCKLETLRLNDCGITDVSSLTQCLTNTKALQFLKVLYLRENHIGDSKQELSDVVRDSNCELSVDEFSLPDFGQIKDIKCCIS", "length": 1370 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCS9-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLQKKNEDEDEESASEMSYPPPESSCVSMKSDWSMVYPPDLSDASVTSDPNNSKRKGQHLEFKESSCVSVMSNRSITPPEMKKIGLKSEDNMLEKIKNKHKTSMKHKYERLFEGVKLHENQTLLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVGVSDASVYSGICTEIFKEESVIQQRKVYSFTHLSIQEFLAAFYVFYYHITCSTEACFDSLHDLQRRAVDKAIESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITSGLRKYACFLTLDPITAHTQLQLSEENRKASIVTDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGLVAVAYKGIGRKSGFDCCFGHNEHSWCLYCSDEVYSVWDNNKSVDVFGPSSRTNRVGVYVDVPSGCLSFYSVSDTNTLTHIHTFNTTFTEELYAGFKVYPGSSVSLCPVKPAEVPP", "length": 988 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUW9-1", "protein_name": "NLR family CARD domain-containing protein 3 isoform X1", "gene_name": "si:ch211-196h16.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKGNTGFRVKPPEPSGVSMKSDRSMHHPLKFKGGIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDPMFRPPEPSVSEKSGQSVDPTLKFSVHTCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDIGEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSINLFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQLDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLRLRCCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLCRCGVSDEGCAALVSVLSSNSSNLRELNLTENKVGDSGVKLLSAGLKENSKLEKLWLFICGVSDEGCAALASILRSNSSNLRELDLTGNKVGDSGVKLLSAGLKDPHCKLEKLTLDFCGVSDEGCAALASALRSNSSNLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC", "length": 1041 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32T552-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:ch73-50f9.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSGKHSVRSGSCVSRSVSLKSDESRKGLPPEFSEQPPSSNRSVEYELSDSVDKTHCNRKSFTDHLLRIFQDLESKIFKVLKNELERFRQILQGENTQDFVKGSNENQSSITKSALDLTLLFLREMKQDEVADTLENELLFINRLKSSLKKTYQSVSEGIAQQGDSTLLNNIYTDLYITQGANEQVNTEHEIRQIEAASRCHKSLEIQVECKHLFEAPEQDKQIRTVLTKGVAGIGKSVSVQKFVVDWAEGKANQDISLIFPLPFREMNLKEKEKQSLKDLITQLFPEVKGLNLTRRTRNKVLFILDGLDECRLPLNFAGNETCHDVSAPAYLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLADQNLAMEIIEHIKQSKSLHIMCHIPVFCWISATVLQNVLKETKVKHKACAKTLQESPKTLTQMYTHFLRFQMQQSRQKYDGKNTDGVSWDQNFILSLGKLAYQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKQETGIILGNLYCFLHLSIQEFIAALYGHLYLDIKKKSVFTGQKHKNKGMTHLLKTAVDKALESDNGHLDLYLRFLLGLSLQTNRQLLRGLLTQQDKSDQSKEEIVVYIKQKLEENLSPERAINLLYCLNELNDHSLMKEIQSHLRDGSLSSADLSPAQWSALTFVLLTSEEELDEFDLQKFKKSDECLIRLSAVIKSSKRALLQCCNLTAQSCESLSSALQSSNCVLRELELSNNDLQDSGVKLLSCGLRSLNCPLEILRLQCCNLTAQSCESLSLALQSSTCVLRELDLSNNDLQDSGVKLISNGLKSCKLEILRLSGCMVTETGCGFLSSALSSNPTHLRELDLSYNHPGVSGVKLLCQKLEDPNYTLAKLNVDHAGAKRITAGPRKWISHLTLDPNTANTELSLSAENREATRVIEKQPYPDHPDRFDYHPQVLCRESVCGPCYWEIDWSGDVGACISVSYKSVSSKGNDEFGCNDQSWSLSCYSSRFSYGHNNRWTDLPVKPISRRIGVYVDHRAETLRFYNICGNTVHLVHSVRTTFTQPLYAGFKIYPGSSVKLC", "length": 1099 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TA29-1", "protein_name": "NLR family CARD domain containing 9 isoform X3", "gene_name": "nlrc9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTKISKDEDYSPRFSSVHQERSDLEPSCVSMRSEQSMGSPMHFRSEDTEADLSSVYQKRSDPEPSCVSMRSDWSMDLPYNFRSEDTPTDLSSFHHKRTEAEFSRVSMRSDMFINHPINIKNVEAQCNIRQNLLNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFESAVRLCDISESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPMFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDEFEQIKKQSLWFKVKDLFQLNSLECVSLFSLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQRLMKLKSRSMQTNKTVKYIKMKIWTIDSPEKSINLFHCLNELGDHSLVKEIQQYLKSGRINRAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAGNNENKKQKVFQKLLPVIKQSRSVLLYNCGLTEMDWDNLTSALRSNPSDLRVLNLSRNILGNSVTLLSAVLEDPCSKLEKLWLSDCGLTDEGCAALATALRSNPEHLRELNLSWNNLRDSVTLLSAVLEDPRCKLETLWLSKCGITGKSCAVLASALRSNPEHLRDLDLSGNKLGDSVTLLSAVLEDPHCKLKILWLSDCGLTDEGCAALASALRSNPGQLRVLDLSENKLKNSGVMQLCAVLEDPHCKLDKLGLYDCSLTDEGCVALASALRSNPEHLRELDLSVNKLRDSGIKLLSAVLEDPRCKLEKLWLSNCGLTDEACAALASALRSNPEHLRELNLSKNKLGESDVKLLSDLKDDTHYKLKELNY", "length": 1079 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TJY6-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkeyp-100h4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQQIQETRLKGDTRASQTISSPSSSCSMAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKDCPPVFSGETPSSAQSVEFESADSGDETHRRHKSFTDNLQSIFQNLESKMFTFLKNELEKFKKILQENRQEIVKEFNENRSRITEAALDLTIFFLREMKQDQAADTLVGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVKCKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDDQKQEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGFVLHTMYCFLHLSIQEFIAALYQHLILDNDKTQAEKSRDESMIDLLKAAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEANLSPERSINLFYCLNELNDQSLLKQIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAIIKTSKRALLQGCYLTVPSCESLSSVLQSSNCVLRGLDLSNNDLQDSGVNLLSDGLKSQHCKLETLRLVMCNLTVESCESLSSVLQSSNFVLRELDLSNNDLQDSGVKLLSDGLKTVNCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVELLFEKLADPNYTLDKLNLDHGGHTRITAGPRKNACFLTLDPNTTYAFLILSEENREVKTVREYQLYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDDYVDISVSYKSIMRKGVDPECVFGRNAQSWSLCCDSSSFTFWHNDTDTRLPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLWPGFTVWCQSSVKLC", "length": 1125 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TMV3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like", "gene_name": "si:ch211-197e7.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDWSKEDPPKFSEKTPSSAQSVRSGSCVSSSVSLKSDRSKEHPLPNFREKTPSSAQSVEHELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNEMEKFKKILQEENRQEFVKDYNENRSRITEAALDLTLFFLREIKQDQAADTLQDELFSINQFQCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNNEHEIRQLEAASRRHQSLETQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNKTCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKILFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALENENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDESKKKIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFMLLTSEEELEEFELRKFQRSDECLIRLSAVIKTSKKALLQSCNVTVQSCKSLSKVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLAMCNLTVQCCESLSLALQSSNCVLRELDLSNNDLQDSGVKLLSNRLKSQYCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDKLNLDHGGEKRITAGLHKYVCFLTLDPNTAHIQLILSEENRKVKPVREDMMMMRKDQPYPDHPDRFDGLYPQVLCRESVCGCCYWETDWSGDGGVCISVSYKSIRRKGGVECEFGRNAQSWSLHCSSSRFIFIHNNTETRLPVKRLSKRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRVYSGSSVKLS", "length": 1140 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TPE7-1", "protein_name": "Protein NLRC3 isoform X4", "gene_name": "si:dkey-11n14.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKYSVRSGSSSSVSLKSDWSKDEPPKFSEKSPSSARSVEYELPYSGDKTHRSHKGFTKDLPRIFQNLESKIIRYLKNELEKFKKILQEENRQDFVKHFNENRSIITEAALDLTLFFLREMKQDEAADTLEGELFFINQLKCGLKKKYQNVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTTGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKENQSLKDLITQFFPQTKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTKLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISANVLLNILKENRNTELKHRDNSETLHESPKTLTQMYTHFLRFQIQHSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYDSDLKDCGIDVYKASVYSGMCTQIFWEETGIILGTMYCFLHLSIQEFIAALYQHLFLDSDKKHLSIFRQKSKNKVMTDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQNDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSADLSPAQWSAVAFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQGCNLNVRCCESLSSALQSSNCLLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDTLNLNHGGEKRITAGPRKYVCFFTLDPNTANTRLILSKKNREVKCVRENQSYPRHPDRFDDHPQVLCRESVCGRCYWEIDWSGGNEVCISVTYKSIRRKRGYECRFGYNAQSWSLICSSSRFSFTHNDTHTDLPVKPFSRRIGVFVDHCAGTLIFYNIYRDTMSLIHSVQTTFTEPLIPGFWVYSGSSVKLLKTEERFTQNPLQDQ", "length": 1060 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQ28-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:ch211-226o13.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTHTSGDLDLFTSCSVDGDDQTRDLQQDSLQPEHDELQRAKNQHKTSMKNKYERLFEGINHGETQKFLNRIYTQLYIIEGESEGVNREHDVLQIEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQGVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITARPAAAHQIPSTYIHRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDQEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFHCYLTDKREPVMLLYESKYSDDEDVSDGNEYEDSDVQFLQSSSEFSLCHLLSLAIYKAVMSSNGHLDLFLWFLLGVSLESNQRLFQDLLTHTEESSESIRIITQDIKDKIKTDDDLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSERELSPAHCSTISYMIEMSEEPLDELDFNKLNTSPVGRWRLIPAVRNCRRALLQWSYLSVQYCESLFSALKSSNCVLRELDLSTNDLQDSGVKLLSDGLKSPNCKLETLRLQCCNLTAQSCESLTSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCKLETLRLVMCNLTVQCCESLSLALQSSNCVLRELDLSNNGLQDSGVKLLSDGLKSQHCKLDTLRLVMCNLTVQSSESLSSALQSSNCVLRELDLSTNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGLHKYACFLTLDPNTTYAFLILSEENREVKRVREYQQYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDGCSVCTAVSYKSIRRKGRGAECLFGRNAQSWSLCCSSSSFIFRHNYTRTELPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFTVWCQSSVKLC", "length": 1145 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQA8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-29j8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEEQVKDSLSEKQSVRSGSCVSSSVSLKSDNSKGGRTPNFRGKTPSSVKRFFHLGKSKHPPSNLREKTPSSAESFQYELPDSRNKTHRSQKSFRGHLQKIFENLESKIIKFVKKELKNFRKILQNENRQEFVKEFNENSSGITEAALDLTLFFLREMKQDQAADTLQGELLYINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSVVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDTQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVLCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNKVMINLLKTAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQCCNLTVQCCESISSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQQCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGEKRITAGPHKYVCFLTLDPNTAHTRLILSEENREVKCVRENQPYPDHPHRFDYYLQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGAECAFGRNAQSWSLICSSSSFTFRHNNSHTDLTVKPLSRRIGVFVDHSAGTLIFYDIYRDTMSLIHSVQTTFTEPLCPGFYVSYGSSVKLS", "length": 1064 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TTK4-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAMNRLMTDMLEELVEAELKQFTRQLWMGVKPGVDPIPRGKLENKDRQDVVDCMVQHYSKDAGKIAVQALRSIKQNERADRLELNLRKDDDFLGEVLKKHKESIKASVDVFEGKKDNKTDINKVYTELFITEGDMTDVCKEHEVQKFDLALQMPRSEDKPIDCNEIFNLLRGKDKGNVVLTKGIAGIGKTFSVNKFILDWAEGRANLDVDCMFLLPFREINLMIKDGDVSLHKFLLKLFPDITGVETTPFYEKCKLLFIFDGLDESRLDLNFNLSSVDDVHSCASIDGLFTSLIKGRLLRSSLIWVTSRPAAANRIPSYHVGLFTEVRGFTDKQKEEYFRKKVPDEDQASRIISHIRTSRSLYIMCHIPVFCWIIATVLQDILQKNKGEDIPSTLTEMYIHFLLIQMNIKNQKYDEKLIRDRTELLGSNRDMISKLAKLAFEQLKKENVMFYREDLAACGINADEEFTGLCTEIFKKDSVLHELKVYYFIHLSVQEFLAALHVFLCYLELEKDMNLTDSDLMFFLEDSRPKQKELLHVLLRKAIDKAEKSDRGHFDLFLRFLLGISLESNQKLLIGILNETKNSKQSISKTVQYLKQLQNNDKCPDKSINHFFCILELQDRTLYQQIMKYLRSKTNRPKVMSRSNCSALVYVLLMSQEVLDKFNPKLFNKTYAGCRILVPAVRCSRKALFSDCGLTETCFETVALALQLENCPLVELDLSYNYSLEAAVNVMCAGLKSPHCHLESLRLAGCHLGQDSCMQVVSALQSISHRLKELDLSGNDLQDSGLQKLLQGMENTEKRLQVLRLSWCNLTEMSCQQLSTILSSNSVFRELDLSNNDLQDSGVKLLSDGLKSPNCKLKILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHCKLKTLKTDPMGDHLMKPGIVKYAFNLTLNPNTAHVHLLLSDGDRKVTLKEKQPYPDDPERFEEHHQVLSRESLSGRCYWETEWTGQEGTVGVAYESIPRKPDDLLYGRCMLGNNIISWKITCGSRTHVSHAEEDITVKSPSSGSCKRVGVYVDTTAGVLSFYHVFDTLTHLYTFLMPFTQPLYAAFRVDGESVSICPIP", "length": 1114 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TUF4-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch73-236c18.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHHCGNEEVDREEKEKHGAEHSCVSMKSDQSMRNPIAFTDKAVTFDLRSVASSSSHFETHTVQEKTDKGLQTQIFETEELQRVKDQHKTSMRKKYELLSEGIKVKETGTQLNRIYTQLYIIEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFYVFYYHVNTTMMGLKTFASLQKLLKGAVDDAIESKNGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCRLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRIKPGLKKYACFLTLDPNTAHVQIQLSEGNREARNVKDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYCCDTNYTVWYNNESADIIAPSARTNRVGVYLDVSSGSLSFYTVSDANTLTLIHTFNTTFTEPLYTGFGLYPESSVSLCQI", "length": 969 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HZJ9-1", "protein_name": "Uncharacterized protein si:ch211-149a19.3 isoform X1", "gene_name": "si:ch211-149a19.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDKEASNDGDFSSRRSHFQSQKSNTSESNPEITPEDLSAKKLIKMFEKRTPDNQSKFNNQKSNTAKSIRSDRSIQNPVKIKEIRTPADLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPKPMPRSIKSDQSTPELDKVDGGHTSTALSSQRSNPPDPKPRSIKSDQSTPEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGIGCQRSNPPDPKPRSIKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPESSLVSLKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSMPEPIKFDGGHTPTGLSETSTNDQFMNKQVKIKRRHTLTGLSKTSINYQFMEKQLKTERRHTSTGLSLNSKLFENLLKSNLLKKFQCVSEGTSILGNPTLLNEIYTELYITESDSGEINNEHELRQIETQSRRSAKEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEKNKNQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEHYKVLFIFDGLDECRVSLDFDSGVKLHDVSESASVDVLLMNLIMGNLLPSALIWITSRPAAADLIPSGFVHRVTEVRGFNDPQKEEYFRKRIRDQSLADTIISHLKSSRSLHIMCHIPVFCWISATVLEKIFSQAERGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEDKDMILKLGKLAFEQLQKGNLIFYEEDLRECGLDLTEAAVYSGLCTQIFREEFGFSQSKVFCFVHLSIQEHLAALYAHHFLTNNCLNKHWKTFNPLSFLHQRAVNEALQSKNGHLDLFLRFLLGLSLEFNQTLLQELLTQTGSCSYNTEETVQFIKQKIREINSPERSINLFHCLNELGDQSLMKEIQNYLRSGEIKETKLSSSQWSALVYVLLTSEQEMEDFDLNQFIGTQNTADEVLQKLQPVVKESRSVQLSGCSVTDKGCAALALVLRSDSSHLRELDLSENNLRDSGVKLLSDGLKDPHCKLEKLRLSDCGVTDEGCAALASALRSNSTHLTELDLSLNNLEDSGVKLLSDGLKDPHCKLEILRLSDCGVTVEGCADLASALRSNSTHLRELDLTLNNLEDSGVNLLSAGLKDPHCKLEKLRLSDCGFTDEGCADLASALRSNSTHLTELDLSLNNFGDSGVKLLSDGLKDPHCKLEKLRLSYCRVRAEGGVALASALRSNPEHLRELDLSENKLGNSGVKMLSELKNDSRYKLDTLKF", "length": 1375 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCJ8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12-like isoform X1", "gene_name": "si:dkeyp-77c4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKEEHLPNFREKTPPSAQSVRSGSCVSSSVSLKSDWSKRDPPNFREKTPSSAKSSVHQKRAEAEPSCVSMKSDWSMNRPITFRSKITQPAISVDRDDQTGHLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSAQKFILDWAEEKDHQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCALTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQIHMRKQKYEERDPEKLLQSNRGVILKLAEVAFSQLMKGNVMFHEEDLTESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVLYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESTESIRRITQHIKDKIKRDKRLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDELDFNKLNTSAEGRRRLTAAVRNCRRALLQGCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLQWCKPTVQSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLVMCNLTVQCCESLSSALQSSNYVLRELDLSNNDLQDSGVKKLSDGLKSPNCKLETLRLVMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKRNCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKWVCFLTLDPNTAHTQLILSEENREVKRVRENQPYPYHPDRFDVHRQVLCRESVCGRCYWEIDWSGDVGVCISVSYKSIRRKGRGVECWFGYNAQSWSLICSSSRFSFRHNHTDTDLPVEPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFTVYSGSSVKLS", "length": 1235 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCK2-1", "protein_name": "Uncharacterized protein si:dkey-26m3.3 isoform X1", "gene_name": "si:dkey-26m3.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGYVFVLSSLCPVFILLQFLLEFLLEIKLFRSIMGNTHAAGDQDLSTECSSVHQKRAEAEPSCVSMKSDASMGVPITFKSENTGPAVSSVHQKRAEAELSCVSMKSDASMNPPIEFKSGNTGPAVSVDRDGQTGDLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEQIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKDNQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPKLEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTEPSSVAVLMRSLLKGDLLPSALIWITSRPAAAHQIPSTYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLDSNQRLFQDLLTHTEESSENIRRITQYIKDEIKRGKHLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELTPAHCSTISYMIEMSEEPLDELDSNKFNTSDVGRRRLIAAVRNCRRALLQRCELTVQCCESLSSALQSSNCVLRELDLSNNDLQDSAVKLLSDGLKSQHCKLETLRLMTCKLTADSCESLSSALQSSNCVLRELDLSNNDLPDSGVKLLSDGLKSQHCKLETLRLQWCKLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLAMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKTVDCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKYVCFLTLDPNTANTRLILSEENREVKHVRENQPYPDHPDRFDGVYQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGVECWFGSNAQSWSLSCSSSNFSFRHNNTRTDLPVKALNRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRIYPGSSVKLS", "length": 1239 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCL0-1", "protein_name": "Uncharacterized protein si:dkey-165o8.1 isoform X1", "gene_name": "si:dkey-165o8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDQSKDHPPYFREETPSSAESVEYESADPGDETHRRHKSFTDNLQSIFQNLESKIIRFLKNELEKFKKILQEENRKEFIKEFIENRSIITEAALDLTLFFLREMKQDQAADTLQDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNKIYTDLYITQGASEQLNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCGDVSSAVSLDVLLTNLIMGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILRLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLDRNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLDIDKKRGWFLIQISKNKSMIDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQFCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKCRTTHTQTHTHTHTHIHTHTHTHTHIHTHTHTHTHTHTRAHTHTHTRGLQQDRANVGPHTYTHTHTHTHTYTYTHTHTHTHTHTHTHTRITAGPRKCRTTHTHTHTYTHTHTHTITHTHLHIHTHTCTHTHTCAHTHTHIHTHTLTHTRTYTHTHTHTLPLTHTHTHTLSHTHTHTHTNIHTHSLTHTNIHTHSLTHTNKHTHSLSHAYTHACMHALSHLHTHTHALTHTHTHTHTHSLTHTHICTHKHTHTLSHSHKHSHTHTHTHTHTHTHTQARAHLHKHTLSHTHTHIHIYTHTYKHTHILSHTHAHTHTHTQARALTQTYSLTHTHTHTHKHTLSHTHTHIHHTHTQIHIHSHKTHTHARTHTLSLSLTHTHTHTHTHTHTHTHTHTHTHTQLWL", "length": 1266 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z7N0-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Dmel\\CG8197", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCDVLLPCEYNPKECPSPAAEKSRLFTILLLYCWQREYDKRPYRQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLRRPQLSVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPREFFVMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANRLLGMSLSLDTEKISSVLSSLLMQNTLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLAMKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISYTYDEALQDYRVVPWR", "length": 387 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZAD9-1", "protein_name": "NLR family, pyrin domain containing 9", "gene_name": "Nlrp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDTSGYGLLKHLRKLSDGEFWSFKELLRKEPEKFKLKPISWMKIENASKEELVMLLNTHYPKQAWDMALSLFLQVNREDLSIMAQKKRRYKQTKYKKFMKTTFQSIWTLESNICIPDRSYHLIVEHQYRKLQNIFDSESEPVTAVVTGPTGEGKTVFLRKAMLDWASGILWQNRFQYVFFFSVLSLNNTTELSLAELISSKLPESSETLNDILSDPKKILFILDGFDYLKFDLELRTNLCNDWRKILPTQIILSSLLQKIMLPESSLLLELGHISLPKIFPLLQYPRDITIQGFSERCLKTYFISFFNTEKGIEVFENLKSNQMLKLCSNPYLCWMFCSCLKWQFDREEEAYFQAKTDSVFFTSFMVSAFKSAYASNPPKQNRAQLKSLCTLAVEGMWKQLFVFDSEDLRRNGISESDKAVWLRMKFLQNHDNHIVFYHPTLQLYFASMFYFLKQDKDTHVPVIGSIPQLLRKIYARDHTQWLQIGIFLFGLATEQVASLLKPYFGFIQHRDVRQEVMRYLKSLSQRECCEKLERPQNLFACLRDNKEEKFVREVVDLFEEITVDITNSHVLSIIANHLQKSSKLKKLHLHIQKRVFLEIHDPEYSDSETFTQDKKNAAEYWKKLCHIFVNLHVLDLDSCNFNKQVIEELCNVLSPSPKIPLMAFKLESLLCSFMTNFGDGSLFHTLLQLPHLKYLNLYGTNLSNSRIENLCSALRRSTCKVEELLHSEMSFPLSTDFIVSHKFGLGKCDISSEACGIIATSLMNSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLETLMLSYCCLTFIACGHLYEALVSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCILKELWLSGCFLTSECCEEISAVLTCNNNLKTLKLGNNDIEDTGVKHLCEALSHPNCKLECLGLDLCKFTSDCCEDLASALTTCKTLNSLNLDWKTLEHSGVVALCEALNHKKCNLKMLGLDKSAFSVESQTLLQAVEKKNNNLSILHYPWVEEERKKRGVRLVWNSKN", "length": 1022 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZP31-1", "protein_name": "NLR family, pyrin domain containing 4", "gene_name": "Nlrp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEILQLRLKQISWTKVKKASREDLANLLLKHYEEKQAWDMTFKIFQKMNRKDLIERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKAQDLFKQKFTQDDCDRFENLLVSKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGIVFQNKFSYIFYFCCQDVKQLKRASLAELISREWPNASAPTAEILSQPEKLLFIIDSLEVMECNMSERESELCDNCTEKQPVSLLLSSLLRRKMLPESSFLISATPETFEKMEDRIECTNVKIITGFNENNIKMYFRSLFQDKNRTLEAFSLVRENEQLFNVCQVPVLCWMVATCIKKEIEKGRDPVFICRRTTSLYTTHIFNLFTPQNAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFSEEALRRNGILDSDIPTLLDRRILERSKESESCYIFLHPSLQEVCAAVFYLLKSHLDHPSQDVKSVEALLFTFLKKAKVQWIFLGCFLFGLLHESEQEKLEMFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEAFLMQAMNCMEQINFVAKDYSDVIVAAYCLKHCSTLKKLSFSTQNILSEEQEHSYTEKLLICWHHMCSVLISSKDIHVLQVKDTNLNETAFWVLYNHLKYPSCTLKVLVVNNVTFLCDNHLFFELIQNQRLQHLNLSLTFLSHSDVKLLCDVLNQAECNIEKLMIAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLCKALCHPDCILKHLVLANCSLSEQCWDYLSEVVRRNKTLSHLDISSNDLKDEGLKVLCGALTLPDSGLISLSVRHCLITTSGCQDLAEVLRHNQNLRSLQVSNNKIEDAGVKLLCDAIKQPNCHLENIGLEACELTGACCKDLASAFVHCKTLWGINLLENALDHSGLVVLFEALKQQKCTLHVLGLRITDFDKETQEFLIAEEEKNPYLSILSNV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZUH1-1", "protein_name": "NLR family, pyrin domain containing 4A", "gene_name": "Nlrp4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLGLKQVSWTEVKKASREDLASLLLKHYEEKQAWDMTFNFFQKINRKDLIKRAKREIDGYPKLYRAHLKTKLTHDSSRIFNINIQDFLKEKFTKDDHDRFETLLQSKGTESKPQVVVLSGVAGIGKTLMLKRLMLAWIEGLVFPYKFSYIFYFCCQEVKQLKTASLAELISREWPDPSAPIEEILSEPEKLLFIIDSLEGIECDLFKCDSELCDNCMEKQPVNILLSSLLRKKMLLEASLLISTTPETFEKMEDRIEYTHVKIITGLNESDIKMCFHRLFQDRNRAQEAFSLVRENEQMLTICQVPVLCWMVATCLKTEIEKGRNLVSTCRRTTSLYTTYIFNLFIPQSAHSPSKKSQDQLQGLCSLAAEGIWTDTFVFTEEALRRNGILDSDIPTLLDIGMLGKMGKFENCYIFLHPSLQEACAAIFYLLKSHGDHPIEDVKSVEALLFTFLKKAKVQWILGGRFIFGLLHESEQKKLEAFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEDFLMEAMNYMEQINFVAKDYSDVIVAAYCLKHCYTLKKLSFSTQNILNEEHEHSCMENLLTCWRHICSVLINSKDIQELQIKDTNLNEPAFSVLYNSLKYCNDTLKVLVENNVFFLCEKYLFFELIQNCNLQHLNLNLTFLSHSDVKLLCDVLNQAECNIEKLEVAACNLSPDDCKMFASILMSSKTLKQLNLSSNILGKGISSLCKSLCHPDCILEHLVLAKCSLSDQCWDYLSDGIRQNKTLNHLDISSNDLKDEGLKVLCRALALPNSVLKSLCLRHCLITTSGCQDLAEVLRNNQNLTSLQISYNKIEDAGVKLLCDAIKQPNCHLEDLGLEACELTGACCEDLASTFTQCRTLWGINLLNNTLDYTGLVVLCEALRQQKCTPHVLGLRITDFDNETQAFLVAEQEKNPDLSILSGV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A1P8-1", "protein_name": "NLR family, pyrin domain containing 4B", "gene_name": "Nlrp4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLFSDFGFMWYWKELNKVEFMKFKELLILEILQMGLKQISWTEVKNASREDLAILLVKYCEGKQAWDTTFKVLQKISRHDLTERATGEIAAHANIYRAHLKKKLTRDCSRKFSISIQNFFQDEYDHLENLLIPKVTEEKPQLVFLKGIAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCQDVKQLKTTSLTELISREWPSSSAPIEEILSQPEKLLFIIDSLEGMEWDFTKQESELCDNCLEKQPVNVLLSSLLKKKILPESSLLISATFETFEELKDWIEYTNVRTITGFKESNIKMYFHSLFQDRNRALEAFSFVRENEQLFTLCQAPVICCMVATCLKNEIEKGKDPVSICRRTTSLYTTHIFNLFIPPNVQYPSKKSQDQLQGLCFLAVEGMWTDISVFSEETLRRNGILDSDIPTLLDIGILEQSRESQNSYIFFHPSVQEFCAAMFYLLQTHMNHPSPDVLHVEKLLFSFLKEVNTQWIFLGRFIFGLLNELEHEKLEAFFGYQLSQQLKQELFEWLELLLDPEVKVNTMKFFYCLFEMEEEVFVQSAMNCREEIDVVAKDYYDFIVAAYCLNHGSALRDLSISTQNVLNEKLNQRYMENLLMLWHNICSVFARNKDIHILQMKDTIFNEPVFQILYNYLKNSSCILEVLVANDVSFLCDKYLFFDLIQSYNLELLDLSGTFLSHSDVVILCNILNKAEYKIQELELANCSLSEQSWKYISDVLCQNKTLRHLDISSNDLKDEGLKVLCKALTLPDSVLLTLSVKACFITTVGCQYLAEVLRNNHKLMFLTLSENKLEDSGVKLLCDAIKHPRCQLAQLDLEACELTGACCEDLASTFTQCKTLGWINLVKNALDFNGLVVLCKALKQKTSNLKELRLRITDFDNKSQTFLLSEEKGNKFLNIENDE", "length": 918 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A523-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWNDACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGRTKMWDRPMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEEEEKRGSQPLDQVQCVFPDPHVACSSRLVNCCLTSSFCRGLFSSLSTNQSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSSQKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTNQNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNCETKRTLEALQEEKPELTVVFEISW", "length": 1035 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FA88-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "nlrc11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYCNYNMDNTRSSRDEDIYSCTSRESEEVLSNTSYWSLPSYFRHRKFHRSSVHEKISDSSESSRVSLKSDWSMNPPPLLGEERKSSNLNMSSLVSVRSDWSMDPPPLLRAKGKSAVSSGVSDNIDWLVCSPYLRVERKSSALRHKLSLLKKFQCLYEGTAVQGKPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLIKDKKFSLVSLLQTFFTREIHLDMIQNSAVIFIFDGLDECRLPFNFSRNEILLDVTKETSVDVLLTNLIVGNLLPYALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILRLGKLAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLLFTNHNINVFEQMTKSFEGTPLNKSDLQSLTLNMELFEISEPVLTDVAAMCEMDWRVVNEISALHCKAVDEVLQNKNGHLDLFLRFLLGLSVECNQILLQRLTKQRRHLYNDNKTVEYIKKKIRTINSPEKSISLFHCLNELGDHSLVEEIQQYLTSGKIKEFKLSSSQWSAVAFVLLTSEKKLEEFWLKEFVGAETKADHVLQKLLPVVKESRKAELSKCGLTEECCAALASALRSKLSHVRELDLSGNKLGDSGIENLSTGLENLHCKLEILRLRSCGITAKGCTALASALRSNPEQIRQLDLSENNIRDWGVKHLFTELKNPDCKLEILGLRNCGITIEGCAALTSALIINPSHLRELDISRNSLGDTGQELLTSLLNSQHHKLEILLLHKFPMTFTSLPSSHSPEMFPQRFRTHNLKE", "length": 966 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q5R7-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSTARDGLYRLSTYLEELEAGELKKFKLFLGIAEDLSQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGEDLVRVTPNNGLCLFESQSACPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPEPPHTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGPWCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTPRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFAAMYCALNGREAVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWSISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQVVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGSAYSTGMEDDPPEPSGVQTQSTYLQERNMLPDVYSAYLSAAVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISGSACQDLAAAVIANRNLIRLDLSDNSIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLSNNSYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVNTCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGISQTLHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFGMDLNKKTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M918-1", "protein_name": "NLR family, pyrin domain containing 14", "gene_name": "Nlrp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTEDEEMEDQLSKEEIVSEDKEFDYRTIIKENFFIIWDKTSLLGESATLNCVTTHKDQKLLEHIFDVNIQTSKSPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLSGREISQEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFALCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMTCQTSTALFTYYICSLFPRIAGSSVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQDTECENCYTFTHLQVQEYFAALFYLLRENPEEKDHPLEPFENVHLLLESNHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLTISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVKVDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDPTAEICLEDAAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLNSCYDFSFLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQSNRSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTKTKRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNNKSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNNSNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNNQSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCPNTESGCWWQYF", "length": 990 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RA38-1", "protein_name": "NLR family pyrin domain containing 2", "gene_name": "Nlrp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHSDQLGFNLKDVLKKLDKTELNNFKSTLKSCSLPQTMKQISKLTMDLANGAQLAEILTDYCPNDWVKRVTFKILEEINRADLAELVMKQVEEAASKASEEKVSSKPREPLKTSLFPQDFVQGDERPEHKHKKEWRNMYTEKWKKNFWPKCNKEIYVDTESYRTLLTLCNPKIEMPFAYTIVLHGPPGSGKTTMARRLMLEWSESKQAQSFSCAFYISCRKLNNSKPCTFAHLLSMNNPSWRYYMIRRLVLSEQFLFVVDGFDELTFPAGALLRDICGDWNTVKPVEVLLSSLLMRKMEPHSTLLVTTQTQSLHQIYLMVDQPVLVETQGFLEPEKQEYFQQYFEDEEGEEEGEGEGKALRALKEVKCNEALFQMASLPAACGIFCLCLELGMKKGEDLALTCQTYTSMFLNFLCRVFLQEACDGHLNKQLQILFKKICILAADSLLEQVPILCEEDFLKLKLNLNKLHPVVYRCIFLEDSSCTNCLSFICLSIQQLLAAIIFVQELGQESKDVSKYSIQKMLSREARLKNPNLSGVLPFVFSLLNKTHIQELETIFGCQISMGVKRKFLECELGENKPFLLLMDLQEIFSCLYESQEEEFVKEAMALFGEVSLHLKTNMDLVHASFCLKNSQNLQTMFLKVEKAVFPENFATLESTAEDQRFQDKKCMLTLWTDFCDTFHSNEKLAFLEIHESFLNSSSLEILCEKLSSAPCHLQKVVLKNISPDDAYEKLCLIFCGYETISHLTLQGGKLDSMLHSLCKVVKNPACNLKFLSLGSCSTTAQKWDDFFPALKANQSLISLDLTDNNLLDKGVRLLCNTWKQSKCILQRVSLENCHLTEVCCKDLSSVLMVSQTLTHLSLAKNELGDNGVKKLCESLSFPKCKLQTLVLWSCNITSNGCHYLSKMLGQAPSLKHLDLGLNRIGTTGAKFLCEALKSPRSNLKSLWLCGCSIIPTNCKDFSEILRSNKSLNTLDLSQNVMGTDAVKIFCESLKLQICPLQTLRLKFDEANPSIQKLIQEMKESHPQLSITSDQVDPKKKSHSFPHFIF", "length": 1048 }, "evidence": [ { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P59046-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "NLRP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQSTCLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELKPSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEGEGGAGPDQDVTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSAGAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIANKNLTRMDLSGNGVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC", "length": 1061 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TKR3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4C", "gene_name": "Nlrp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLRLKQISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRKDLMERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKVQDFSKQKFTQDDYDRFENFLISKVTAKKPHMVFLQGAAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPKTSAPIEDILSQPEKLLFVIDNLEVMECDMSERESELCDTCTEKQPVRILLSSLLRRKMLPKSSFLISATPETFEKMEGRVECTNVKIVTGFNESNIKMYFRSLFQDKTKTQEIFSLVKENQQLFTVCQVPVLCWMVATCLKKEIEKGRDLVSVCRRTTSLYTTHIFNLFIPQSAQYPSKESQAQLQSLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPTLLDVRILEKSKKSEKSYIFLHPSIQEVCAAIFYLLKSHMDHPSQDVKSIEALIFTFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQVDGMKLFYCLFEMDDEAFLAQAMNCMEQINFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNVLSEGQEHSYTEKLLMCWHHMCSVLISSKDIYILQVKNTNLNETASLVLYSHLMYPSCTLKALVVNNVTFLCDNRLFFELIQNQCLQHLDLNLTFLSHGDVKLLCDVLSQEECNIEKLMVAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLVNCSLSEQCWDYLSEVLRRNKTLNHLDISSNDLKDEGLKVLCGALSLPDSVLKSLSVRYCLITTSGCQDLAEVLRKNQNLRNLQVSNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASAFTHCKTLWGINLQENALDHSGLIVLFEALKQQQCTLHVLGLRITDFDKETQELLMAEEEKNPHLSILSSV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X03-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9A", "gene_name": "Nlrp9a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDSSGYGLLQYLQKLSDEEFQRFKEHLRKEPEKFKLKPISWTKIKNTSKEDLVMQLYTHYPGKAWDMVLSLFLQVNREDLSTMAQTERRDKQTKYKEFMKNTFQHIWTMETNTYIPDRSYHEFIEVQYRALQDIFDCESEPVTVVVSGSRGGGKTTFLRKAMLDWASRNLLQNRFQYVFHFSVFSLNNITELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKKLPIQIVLSSLLQKIMLPECSLLLELGNASLSNIIPLLQYPREIIMSGFSEQTIEIYCVSFFNTQTGVEIFKNLKSIKPLFNLCRCPHLCWMICSTIKWQYERREVASRFGRTLGLLYTIFMVSAFKSTYARNPSKQNRARIRTLCTLAVEGMWKQVYVFDSDDLRRNGISESDKKVWLRMKFLQNQGSNIVFYHSTLQWYFAVLFYFLQYKDTRHPVIGNLAQLLGEIYAHKQNQWFHTRILLFGMATEQVNSLLEPCFGCISSKEVRQEIIRYIKSLSQQECNEKLVVHPQNLFFCILDNQEERFVRQLMDRFEEMTVDISDVDDMSATPYCLHRAPKVKNLHLHIQKRVFLEIHDPEYGDLELFKLGQKCSFTTNFGDGLLFCTFLHLPHLKYMNLYGTNLSNDAVERLCSALKFSTCGVEELLLGKCDISSEACGIIAASLINSEVKHLSLVENPLKNKGVMSLCEMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNEHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCYLTSECCEEISAVLTCNTNLKTLKLGNNNIQDTGVKRLCEALCHPNCEMQCLGLDMCDFTSDCCEDLALVLTTCNTLKSLNLDWNAFDHSGLEMLCKALNHKACNLEVLGLDKSLFSEESQTLLQAVEKKNKNLKVLHFPWLKEELEKRGVRLVWNSKN", "length": 949 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X05-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4F", "gene_name": "Nlrp4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFISDFGLIWYLRELNKKEFMKFKDFLIQEILELKLKQVSSTKVKKASREDLANLLLKCGENQAWDMTFRILQKINRKDLTERATGAIVGNPNLYRDHLKKKLTHDCPKKFNVRIQDFIKETFIQNDXDAFENLLISKGTERKPHMVFLKGMAGVGKTLMLKNLMLAWSKGLVFQNKFSYAFYFCCQDVKQLKTASLAELISREWPSPSAPIEEILSQPEKLLFIIDSLEGMEWDLTKQESELCDDCMEKQPVSTLLSSLLRRKMLPESSLLLSTTPETFEKMEDRIQCTDVKTATAFDERSMKIYFHRLFQDRKRAQEAFSLVRENKQLFTICQVPLLCWMVATCLKEEIEKGGDPVSLCRRTTSLYTTHIFSLFIPQSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFGKEALRRNGIFDSDIPTLLDIGMLGKIREFENSYIFLHPSVQEVCAAIFYMLKRHVEHPSQDVKNIETVLFMFLKKVKTQWIFLGCFIFGLLQKSEQEKLGVFFGHRLSKNIHHKLYQCLETLSGNAELQEQIDGMRLFSCLFEMEDEAFLVKAMNCMQQINFVAKNYSDFIVAAYCLKHCSTLKKLSFSTENVLNEGDQSYMEELLICWNNMCSVFVRSKDIQELRIKDTNFNEPAIRVLYESLKYPSFTLNKLVANNVSFGDNHVLFELIQNSSLQYLDLSCSFLSHNEVKLLCDILNQAECNIEKLMIAHCKLSPDDCKIFGSILMSSKSLKVLNLASNNLNQGISSLCKALCHPHCTLEYLVPRSNHCIVNFLLKLSCCGITERGCQDLAEVLKNNQNLKYLHVSYNKLKDTGVMLLCDAIKHPNCHLKDLQLEACEITDASNEELCYAFMQCETLQTLNLMGNAFEVSRMVFFPRKSELMLFIFLHLSRLWITDFDNEFQAFLLSVKKKNHFLTIRGSVEADGEKKGGDSDARTMGELSNEI", "length": 959 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X19-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4E", "gene_name": "Nlrp4e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKELLQQEILQLGLKHISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRQDLMERAGREIAGHSKLYQVHLKKKLTHDYARKFNIKDQDSLKQKFTQDDCDHFENLLISKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPNASAPIEEILSQPEKLLFVIDNLEVMECDMSEWESELCDDCMEKQPVNILMSSLLRRKMLPESSFLVSATPETFEKIEDRIECTNVKMMAGFNESSIKVYFYSLFQDRNRTQEIFSLVRENEQLFSVCQVPVLCWMVATCLKKEIEKGRDPVSICRRITSLYTTYIFNLFIPHSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFAEEALRRNGIMDSDISTLLDVRILEKSKESEKSYIFLHPSIQEVCAAIFHLLKSHVDHPSQDVKSIEALIFTFLKKVKIQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNKELQEQIDGMKLFYCLFEMDDEAFLPQVMNCMEQIKFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNILSEGQEHSYTEKLLICWHHVCSVLTSSKDIHVLQVKDTNFNERAFLVLYSHLKYPSCILKVLEVNNVTLLCDNRLLFELIQNQRLQLLNLSLTFLSHNDVKLLCDVLNQAECNIEKLMVADCNLSPDDCKVFVSVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLAKCSLSEECWHYLSEVLRRNKTLTHLDISFNDLKDEGLKVLCGALTLPDSVLISLSVRYCLITTSGCQDLAEVLRNNQNLRNLQISNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASSFTHCKTLLGINLQENALDHSGLVALFEAMKQQQCTVNLRGLRITDFDKETQEFLMAEKEKNPYLSI", "length": 978 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X22-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9B", "gene_name": "Nlrp9b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSSGYGLLKLLQKLSDEEFQRFKELLREEPEKFKLKPISWTKIENSSKESLVTLLNTHYPGQAWNMMLSLFLQVNREDLSIMAQKKKRHKQTKYKKFMKTTFERIWTLETNTHIPDRNYHLIVEVQYKALQEIFDSESEPVTAIVAGTTGEGKTTFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKRLPTQIVLSSLLQKIMLPGCSLLLELGQISVPKIRHLLKYPRVITMQGFSERSVEFYCMSFFDNQRGIEVAENLRNNEVLHLCSNPYLCWMFCSCLKWQFDREEEGYFKAKTDAAFFTNFMVSAFKSTYAHSPSKQNRARLKTLCTLAVEGMWKELFVFDSEDLRRNGISESDKAVWLKMQFLQTHGNHTVFYHPTLQSYFAAMFYFLKQDKDICVPVIGSIPQLLGNMYARGQTQWLQLGTFLFGLINEQVAALLQPCFGFIQPIYVRQEIICYFKCLGQQECNEKLERSQTLFSCLRDSQEERFVRQVVDLLEEITVDISSSDVLSVTAYALQKSSKLKKLHLHIQKTVFSEIYCPDHCKTRTSIGKRRNTAEYWKTLCGIFCNLYVLDLDSCQFNKRAIQDLCNSMSPTPTVPLTAFKLQSLSCSFMADFGDGSLFHTLLQLPHLKYLNLYGTYLSMDVTEKLCAALRCSACRVEELLLGKCGISSKACGIIAISLINSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLQSLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCFLTSQCCEEISAVLICNRNLKTLKLGNNNIQDTGVRQLCEALSHPNCNLECLGLDLCEFTSDCCKDLALALTTCKTLNSLNLDWKTLDHSGLVVLCEALNHKRCNLKMLGLDKSAFSEESQTLLQDVEKKNNNLNILHHPWFEAERNKRGTRLVWNSRN", "length": 1003 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6B966-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "Nlrp14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTEDDEMEYEASKEETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITPKDQNLLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLNGKEISQVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFALCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVGCVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQDTEYENCYMFTHLHVQEFFAALFYLLRENLEEQDYPSEPFENLYLLLESNHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVRVDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLDTAEMCLEGAAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLNGCQDFTFLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTKSKRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHNRSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNNSNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNNKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECPNTESGCWWNYF", "length": 993 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTR0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9", "gene_name": "NLRP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESFFSDFGLLWYLKELRKEEFWKFKELLKQPLEKFELKPIPWAELKKASKEDVAKLLDKHYPGKQAWEVTLNLFLQINRKDLWTKAQEEMRNKLNPYRKHMKETFQLIWEKETCLHVPEHFYKETMKNEYKELNDAYTAAARRHTVVLEGPDGIGKTTLLRKVMLDWAEGNLWKDRFTFVFFLNVCEMNGIAETSLLELLSRDWPESSEKIEDIFSQPERILFIMDGFEQLKFNLQLKADLSDDWRQRQPMPIILSSLLQKKMLPESSLLIALGKLAMQKHYFMLRHPKLIKLLGFSESEKKSYFSYFFGEKSKALKVFNFVRDNGPLFILCHNPFTCWLVCTCVKQRLERGEDLEINSQNTTYLYASFLTTVFKAGSQSFPPKVNRARLKSLCALAAEGIWTYTFVFSHGDLRRNGLSESEGVMWVGMRLLQRRGDCFAFMHLCIQEFCAAMFYLLKRPKDDPNPAIGSITQLVRASVVQPQTLLTQVGIFMFGISTEEIVSMLETSFGFPLSKDLKQEITQCLESLSQCEADREAIAFQELFIGLFETQEKEFVTKVMNFFEEVFIYIGNIEHLVIASFCLKHCQHLTTLRMCVENIFPDDSGCISDYNEKLVYWRELCSMFITNKNFQILDMENTSLDDPSLAILCKALAQPVCKLRKLIFTSVYFGHDSELFKAVLHNPHLKLLSLYGTSLSQSDIRHLCETLKHPMCKIEELILGKCDISSEVCEDIASVLACNSKLKHLSLVENPLRDEGMTLLCEALKHSHCALERLMLMYCCLTSVSCDSISEVLLCSKSLSLLDLGSNALEDNGVASLCAALKHPGCSIRELWLMGCFLTSDSCKDIAAVLICNGKLKTLKLGHNEIGDTGVRQLCAALQHPHCKLECLGLQTCPITRACCDDIAAALIACKTLRSLNLDWIALDADAVVVLCEALSHPDCALQMLGLHKSGFDEETQKILMSVEEKIPHLTISHGPWIDEEYKIRGVLL", "length": 991 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W24-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "NLRP14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSSSSSFFPDFGLLLYLEELNKEELNTFKLFLKETMEPEHGLTPWNEVKKARREDLANLMKKYYPGEKAWSVSLKIFGKMNLKDLCERAKEEINWSAQTIGPDDAKAGETQEDQEAVLGDGTEYRNRIKEKFCITWDKKSLAGKPEDFHHGIAEKDRKLLEHLFDVDVKTGAQPQIVVLQGAAGVGKTTLVRKAMLDWAEGSLYQQRFKYVFYLNGREINQLKERSFAQLISKDWPSTEGPIEEIMYQPSSLLFIIDSFDELNFAFEEPEFALCEDWTQEHPVSFLMSSLLRKVMLPEASLLVTTRLTTSKRLKQLLKNHHYVELLGMSEDAREEYIYQFFEDKRWAMKVFSSLKSNEMLFSMCQVPLVCWAACTCLKQQMEKGGDVTLTCQTTTALFTCYISSLFTPVDGGSPSLPNQAQLRRLCQVAAKGIWTMTYVFYRENLRRLGLTQSDVSSFMDSNIIQKDAEYENCYVFTHLHVQEFFAAMFYMLKGSWEAGNPSCQPFEDLKSLLQSTSYKDPHLTQMKCFLFGLLNEDRVKQLERTFNCKMSLKIKSKLLQCMEVLGNSDYSPSQLGFLELFHCLYETQDKAFISQAMRCFPKVAINICEKIHLLVSSFCLKHCRCLRTIRLSVTVVFEKKILKTSLPTNTWDGDRITHCWQDLCSVLHTNEHLRELDLYHSNLDKSAMNILHHELRHPNCKLQKLLLKFITFPDGCQDISTSLIHNKNLMHLDLKGSDIGDNGVKSLCEALKHPECKLQTLRLESCNLTVFCCLNISNALIRSQSLIFLNLSTNNLLDDGVQLLCEALRHPKCYLERLSLESCGLTEAGCEYLSLALISNKRLTHLCLADNVLGDGGVKLMSDALQHAQCTLKSLVLRRCHFTSLSSEYLSTSLLHNKSLTHLDLGSNWLQDNGVKLLCDVFRHPSCNLQDLELMGCVLTNACCLDLASVILNNPNLRSLDLGNNDLQDDGVKILCDALRYPNCNIQRLGLEYCGLTSLCCQDLSSALICNKRLIKMNLTQNTLGYEGIVKLYKVLKSPKCKLQVLGLCKEAFDEEAQKLLEAVGVSNPHLIIKPDCNYHNEEDVSWWWCF", "length": 1093 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W25-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 13", "gene_name": "NLRP13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFSVITCPNGGTNQGLLPYLMALDQYQLEEFKLCLEPQQLMDFWSAPQGHFPRIPWANLRAADPLNLSFLLDEHFPKGQAWKVVLGIFQTMNLTSLCEKVRAEMKENVQTQELQDPTQEDLEMLEAAAGNMQTQGCQDPNQEELDELEEETGNVQAQGCQDPNQEEPEMLEEADHRRKYRENMKAELLETWDNISWPKDHVYIRNTSKDEHEELQRLLDPNRTRAQAQTIVLVGRAGVGKTTLAMQAMLHWANGVLFQQRFSYVFYLSCHKIRYMKETTFAELISLDWPDFDAPIEEFMSQPEKLLFIIDGFEEIIISESRSESLDDGSPCTDWYQELPVTKILHSLLKKELVPLATLLITIKTWFVRDLKASLVNPCFVQITGFTGDDLRVYFMRHFDDSSEVEKILQQLRKNETLFHSCSAPMVCWTVCSCLKQPKVRYYDLQSITQTTTSLYAYFFSNLFSTAEVDLADDSWPGQWRALCSLAIEGLWSMNFTFNKEDTEIEGLEVPFIDSLYEFNILQKINDCGGCTTFTHLSFQEFFAAMSFVLEEPREFPPHSTKPQEMKMLLQHVLLDKEAYWTPVVLFFFGLLNKNIARELEDTLHCKISPRVMEELLKWGEELGKAESASLQFHILRLFHCLHESQEEDFTKKMLGRIFEVDLNILEDEELQASSFCLKHCKRLNKLRLSVSSHILERDLEILETSKFDSRMHAWNSICSTLVTNENLHELDLSNSKLHASSVKGLCLALKNPRCKVQKLTCKSVTPEWVLQDLIIALQGNSKLTHLNFSSNKLGMTVPLILKALRHSACNLKYLCLEKCNLSAASCQDLALFLTSIQHVTRLCLGFNRLQDDGIKLLCAALTHPKCALERLELWFCQLAAPACKHLSDALLQNRSLTHLNLSKNSLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTREGCGELANALSHNHNVKILDLGENDLQDDGVKLLCEALKPHRALHTLGLAKCNLTTACCQHLFSVLSSSKSLVNLNLLGNELDTDGVKMLCKALKKSTCRLQKLG", "length": 1043 }, "evidence": [ { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BU40-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4A", "gene_name": "Nlrp4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEVLQLGLKQVSWTEVKKASRQDLASLLLKHYEEKPAWDMTFRFFQKINRKDLIERAKREIDGCPKLYRAHMKTKMTHDSSRAFTISIQNFLKEKFTEDDYDCFENLFQSKGTESKPQVVFLSGGAGVGKTLMLKRLMLAWIESPVFLHKFSYIFYFCCREVKQLKTASLAELISREWPGPSAPIEEILSKPEKLLFIIDSLEGMECDLFKWESELCDNCTEKQPVNVLLSSLLRRKMLPESSLLISATPESFEKMENRIEYTHVKIIKGLKERNIKMSFHRLFQDRNRAHEAFSLVRENEQLFTVCQVPVLCWMVATCLKEEIEKGRDPVSICRCTTSLYTTHIFNLFIPQNAHSPSKKSQDQLQGLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPILLDIGMLINIRESEKSYIFLHPSVQEVCAAIFYLLKSHVDHPSQEVKSIEKLMFAFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQIDGMKLFYCLFEMDDDTFLVEAMNCMEQINFVAKDYSDVIVAAHCLKHCFTLKKLSFSTQNVLSGAQEHSYMERLLTAWNHICSVFIISKDIQELRMKDTNLSESAFSVLYNNLKYHNYTLNVLVANNVFFVCEKYLFFELIQNCNLQHLNLSLTILSHSDVKLLCDVLSQAECNIEELVVAACSISSDDCKVFASVLISNKTLKHLNLASNTLDKGIASLCKSLCHPDCILEHLVLANCSLNEKCWDYLSEVLRRNKTLSHLDISSNDLKDEGLKVLCRALTLPDSVLKSLSLRHCLITISGCQDLAEVLRNNQNLVSLQVSNNKLEDTGVKLLCDAIKHPNCHLEDLGLEACELTGACCEDLASTFTQCKTLWAMNLLKNALDYNGLVVLCEALKQQTCATYVLGLQITDFDTETQAFLVAEQEKNPCLRILSSL", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C6J9-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4B", "gene_name": "Nlrp4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLFSDFGFIWYWKELNKIEFMYFKELLIHEILQMGLKQISWTEVKEASREDLAILLVKHCDGNQAWDTTFRVFQMIGRNVITNRATGEIAAHSTIYRAHLKEKLTHDCSRKFNISIQNFFQDEYDHLENLLVPNGTENNPKMVVLQGVAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCHDVKQLQTASLADLISREWPSPSAPMEEILSQPEKLLFIIDSLEGMEWNVTQQDSQLCYNCMEKQPVNVLLSSLLRKKILPESSLLISTSCETFKDLKDWIEYTNVRTITGFKENNINMCFHSLFQDRNIAQEAFSLIRENEQLFTVCQAPVVCYMVATCLKNEIESGKDPVSICRRTTSLYTTHILNLFIPHNAQNPSNNSEDLLDNLCFLAVEGMWTDISVFNEEALRRNGIMDSDIPTLLDIGILEQSRESENSYIFLHPSVQEFCAAMFYLLHSEMDHSCQGVYFIETFLFTFLNKIKKQWVFLGCFFFGLLHETEQEKLEAFFGYHLSKELRRQLFLWLELLLDTLHPDVKKINTMKFFYCLFEMEEEVFVQSAMNCREQIDVVVKGYSDFIVAAYCLSHGSALTDFSISAQNVLNEELGQRGKLLILWHQICSVFLRNKDIKTLRIEDTIFNEPVFKIFYSYLKNSSCILKTLVAYNVSFLCDKRLFLELIQSYNLEELYLRGTFLSHSDVEMLCDILNQAECNIRILDLANCSLCEHSWDYLSDVLRQNKSLRYLNISYNNLKDEGLKALCRALTLPNSALHSLSLEACQLTGACCKDLASTFTRYKCLRRINLAKNSLGFSGLFVLCKAMKDQTCTLYELKLRMADFDSDSQEFLLSEMERNKILSIENGV", "length": 863 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4B8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWNDTCTSHSSMVCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIGRTKMRDSPMSSLKLELLFEPEDGHSEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSDYLQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFFHNSPKEEEEERRGGRPLDQVQCVFPDTHVACSSRLVNCCLTSSFCRGLFSSLSTNRSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSSSQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTNQNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHNHSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNRETKRALEALQEEKPELTIVFEISW", "length": 1033 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96MN2-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4", "gene_name": "NLRP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQMTLQLELKQIPWTEVKKASREELANLLIKHYEEQQAWNITLRIFQKMDRKDLCMKVMRERTGYTKTYQAHAKQKFSRLWSSKSVTEIHLYFEEEVKQEECDHLDRLFAPKEAGKQPRTVIIQGPQGIGKTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELRELPPTSLADLISREWPDPAAPITEIVSQPERLLFVIDSFEELQGGLNEPDSDLCGDLMEKRPVQVLLSSLLRKKMLPEASLLIAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQLFSICQIPLLCWILCTSLKQEMQKGKDLALTCQSTTSVYSSFVFNLFTPEGAEGPTPQTQHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGERESSYVFLHVCIQEFCAALFYLLKSHLDHPHPAVRCVQELLVANFEKARRAHWIFLGCFLTGLLNKKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFVKQAVNLLQEANFHIIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFKKEDEHSSTSDYSLICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFSGQSVLLFEVLFYQPDLKYLSFTLTKLSRDDIRSLCDALNYPAGNVKELALVNCHLSPIDCEVLAGLLTNNKKLTYLNVSCNQLDTGVPLLCEALCSPDTVLVYLMLAFCHLSEQCCEYISEMLLRNKSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDLASALISNQNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLASVLTCSKTLQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRKTDFDEETQALLTAEEERNPNLTITDDCDTITRVEI", "length": 994 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW", "length": 1036 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9NX02-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 2", "gene_name": "NLRP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1062 }, "evidence": [ { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081103-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081103-19#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z047", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z047" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z047", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z047" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { 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"title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M6Z062-1", "uniprot_ac": "A0A8M6Z062", "uniprot_id": "A0A8M6Z062_DANRE", "mass": { "chemical_mass": 49154.0, "monoisotopic_mass": 49154.0 }, "refseq": { "ac": "XP_017211180", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211180" }, "gene_names": [ { "name": "LOC103910825", "type": "recommended", "evidence": [ { "id": "A0A8M6Z062", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z062" } ] }, { "name": "LOC103910825", "type": "synonym", "evidence": [ { "id": "XP_017211180", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211180" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M6Z062", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z062/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017211180", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211180" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211180" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z062", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z062#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z062", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z062" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC103910825", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z062", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z062", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z062", "database": "AlphaFoldDB", "categories": [] }, { "id": "103910825", "url": "https://www.ncbi.nlm.nih.gov/gene/103910825", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:103910825", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910825", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z062", "url": "https://www.orthodb.org/?gene=A0A8M6Z062", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", 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"MAFIKEESEDVKIEETFTVKQEDLQEQTDLIEEKEGSKEEEHHVKIEEKTHLQTDGILKRRDKNRFTCTQCGKSLASKSSLKIHMSIHTGKKSFTCLQCGKSFNQISALSKHKKIHTGEKPYTCTQCGKSFSQSSNFNLHMRIHTGEKPFTCTQCGKSFTCSSHLNQHMRIHSGEKPFSCSQCGKCFNCSSHFKQHMRIHTGEKPFTCTQCGKSFSQSSNFNLHMRIHTGQKPFTCTQCGKSFSQSSDLNKHMMSHTGEKPFTCTQCGNSFIRSSHLNQHMRIHTGEKPFTCTQCGKSFNCSSHLNQHMRIHTGEKSFTCTQCGKSFSQSSNLNQHMKIHTGEKPFTCTQCRKSFSQSSSLNDHMKIHTGEKPFTCTQCGKSFNRSSNLNKHMRIHTGEKPFTCTQCGKSYSRSSSLHLHMLSHTGEKPFTCT", "length": 433, "header": "tr|A0A8M6Z062-1|A0A8M6Z062_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC103910825 PE=4 SV=1 CANONICAL=A0A8M6Z062-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z062-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z062/entry#A0A8M6Z062-1", "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDLQEQTDLIEEKEGSKEEEHHVKIEEKTHLQTDGILKRRDKNRFTCTQCGKSLASKSSLKIHMSIHTGKKSFTCLQCGKSFNQISALSKHKKIHTGEKPYTCTQCGKSFSQSSNFNLHMRIHTGEKPFTCTQCGKSFTCSSHLNQHMRIHSGEKPFSCSQCGKCFNCSSHFKQHMRIHTGEKPFTCTQCGKSFSQSSNFNLHMRIHTGQKPFTCTQCGKSFSQSSDLNKHMMSHTGEKPFTCTQCGNSFIRSSHLNQHMRIHTGEKPFTCTQCGKSFNCSSHLNQHMRIHTGEKSFTCTQCGKSFSQSSNLNQHMKIHTGEKPFTCTQCRKSFSQSSSLNDHMKIHTGEKPFTCTQCGKSFNRSSNLNKHMRIHTGEKPFTCTQCGKSYSRSSSLHLHMLSHTGEKPFTCT", "length": 433, "header": "tr|A0A8M6Z062-1|A0A8M6Z062_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC103910825 PE=4 SV=1 CANONICAL=A0A8M6Z062-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103910825", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910825", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213565" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0U5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rtn4rl1a", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091118-38", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-38", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z0U5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z0U5", "database": "AlphaFoldDB", "categories": [] }, { "id": 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"categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z0U5", "url": "https://www.orthodb.org/?gene=A0A8M6Z0U5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213565", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z0U5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z0U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091118-38", "url": "https://zfin.org/ZDB-GENE-091118-38", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFRRGCGLEFLLVLCGLELTQACPRHCICYDSPSTVSCQAHNFQVVPEGIPAQSERVFLQNNKIQRLLQGHFSPTTVMLWLYSNNISYIQPSTFMGFTRLEELDLGDNKHLRSLASDTFQGLTRLHALHLYHCGLITLPAGLFEGLHNLQYLYLQSNQLEFLEDDMFIDLLNLSHLFLHGNRLWSLHQNTFRGLGALDRLLLHQNRLQWVHKQAFHDLRRLTTLYLFNNSLPELPAESLSQLPALEYLRLNDNPWECDCKAVPLWDWLRRFRGSTSALICTAPPELVGKDLKQLTKEQLPSCTGSESLHQSKSSNQGDVGVSLKKDHHHRSHNRHHHHPHLPHQDQYYPTSPSPIPRPPKSGRNRNCTRHRGRKGNGQNEVYNLKDLGNKESDDKYDPTKPRRKNKCIPRTSVGPPSGVQRANSRATSLLAPGFIIPLCLLVCLTALIFR", "length": 450, "header": "tr|A0A8M6Z0U5-1|A0A8M6Z0U5_DANRE Isoform 1 of Reticulon-4 receptor-like 1 OS=Danio rerio OX=7955 GN=rtn4rl1a PE=3 SV=1 CANONICAL=A0A8M6Z0U5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z0U5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U5/entry#A0A8M6Z0U5-1", "sequence": { "sequence": "MFRRGCGLEFLLVLCGLELTQACPRHCICYDSPSTVSCQAHNFQVVPEGIPAQSERVFLQNNKIQRLLQGHFSPTTVMLWLYSNNISYIQPSTFMGFTRLEELDLGDNKHLRSLASDTFQGLTRLHALHLYHCGLITLPAGLFEGLHNLQYLYLQSNQLEFLEDDMFIDLLNLSHLFLHGNRLWSLHQNTFRGLGALDRLLLHQNRLQWVHKQAFHDLRRLTTLYLFNNSLPELPAESLSQLPALEYLRLNDNPWECDCKAVPLWDWLRRFRGSTSALICTAPPELVGKDLKQLTKEQLPSCTGSESLHQSKSSNQGDVGVSLKKDHHHRSHNRHHHHPHLPHQDQYYPTSPSPIPRPPKSGRNRNCTRHRGRKGNGQNEVYNLKDLGNKESDDKYDPTKPRRKNKCIPRTSVGPPSGVQRANSRATSLLAPGFIIPLCLLVCLTALIFR", "length": 450, "header": "tr|A0A8M6Z0U5-1|A0A8M6Z0U5_DANRE Isoform 1 of Reticulon-4 receptor-like 1 OS=Danio rerio OX=7955 GN=rtn4rl1a PE=3 SV=1 CANONICAL=A0A8M6Z0U5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100004523", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004523", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0U5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U5" } ], "pmid": "" }, { "name": "perikaryon", "id": "GO:0043204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043204", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0U5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U5" } ], "pmid": "" }, { "name": "membrane raft", "id": "GO:0045121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045121", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0U5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U5" } ], "pmid": "" }, { "name": "cell projection", "id": "GO:0042995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042995", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0U5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z0U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U5" }, { "id": "SM00082", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00082" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRCT", "eco_id": "ECO_0000259", "start_pos": 253, "end_pos": 303, "start_aa": "Asn", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 366, "end_pos": 368 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z0U9-1", "uniprot_ac": "A0A8M6Z0U9", "uniprot_id": "A0A8M6Z0U9_DANRE", "mass": { "chemical_mass": 40113.0, "monoisotopic_mass": 40113.0 }, "refseq": { "ac": "XP_017213576", "name": "trace amine-associated receptor 13c-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213576" }, "gene_names": [ { "name": "taar20b", "type": "recommended", "evidence": [ { "id": "A0A8M6Z0U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U9" } ] }, { "name": "taar20b", "type": "synonym", "evidence": [ { "id": "XP_017213576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213576" } ] } ], "protein_names": [ { "name": "Trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "A0A8M6Z0U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U9/entry#names_and_taxonomy" } ] }, { "name": "trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "XP_017213576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213576" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017213576.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213576" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "taar20b", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060414-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060414-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd15055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100001562", "url": "https://www.ncbi.nlm.nih.gov/gene/100001562", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100001562", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001562", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z0U9", "url": "https://www.orthodb.org/?gene=A0A8M6Z0U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249:SF381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249:SF381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213576", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213576", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z0U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z0U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060414-1", "url": "https://zfin.org/ZDB-GENE-060414-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKEQKGEQNKHLTGGDSLMAYETEDQETQYCFPDINSSCLKENRSSDEYNIIYLLVSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLVMPIEAFRLIETCWYFGDTFCGLYLFFVTLLLSASLGSLVLIAVDRYVAVCHPLLYTQKITMTKTFCLSICLSWVCFSAYLTGLININNQDFDTSHRTDVCYGQCIIMITFSWILTDLFVSFIFPCTLIFTLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVERKSESKAALTLGIIVLVYLLCYIPYYICSLTVNSSTALNVLIWIVYSNSGMNPLVYALFYPWFKKTVKLILTLKIFQQASSLINIFTEH", "length": 352, "header": "tr|A0A8M6Z0U9-1|A0A8M6Z0U9_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=taar20b PE=3 SV=3 CANONICAL=A0A8M6Z0U9-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z0U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U9/entry#A0A8M6Z0U9-1", "sequence": { "sequence": "MKEQKGEQNKHLTGGDSLMAYETEDQETQYCFPDINSSCLKENRSSDEYNIIYLLVSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLVMPIEAFRLIETCWYFGDTFCGLYLFFVTLLLSASLGSLVLIAVDRYVAVCHPLLYTQKITMTKTFCLSICLSWVCFSAYLTGLININNQDFDTSHRTDVCYGQCIIMITFSWILTDLFVSFIFPCTLIFTLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVERKSESKAALTLGIIVLVYLLCYIPYYICSLTVNSSTALNVLIWIVYSNSGMNPLVYALFYPWFKKTVKLILTLKIFQQASSLINIFTEH", "length": 352, "header": "tr|A0A8M6Z0U9-1|A0A8M6Z0U9_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=taar20b PE=3 SV=3 CANONICAL=A0A8M6Z0U9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100001562", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001562", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PV58-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19m", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKEKRSIREYIIMYLFSSLLSVWIVFLNLLVIISISHFKKLHTPTNMIILSLAVADLLIGLIVMPLQAIKQIETCWYFGESFCGINLILIGLIFSASFSNLVLIAVDRYVAVCHPLLYPRKITTAKMLMSILLSWLYYSGYNTGLVINNGYADTSYRTDMCYGECTIIMSFGWILTDMFMFFIFPCLIMITFYVRIFYVVHQQVKVMNSLMKGGKCVTEGSVKRKSESKAALTLGIIVTVYLLCYIPYYICTLSVNSVTAINVLGWIVYANSGVNPLVYALFYPWFKKTAKIILTLKIFEPASSLINIFK", "length": 331 }, "evidence": [ { "id": "HGNC:20978", "url": "https://alliancegenome.org/gene/HGNC:20978#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z8X7-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19u", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKGKRSRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLFVIPIQAIKLTETCWYFGDIFCVLYLILIGLIFSASLSNLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNTAFVVNNGYFDSSHRTDMCNGRCSVMVSFSWTVIDLFMCFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKRVTESSAKRKSESKAALTLGIIVTIYLLCYIPYYICSLFVISSTTITVLSWAVHANSGLNPLVYALFYSSFKKTVKHIFTLKIFQPVSFLFRIFK", "length": 331 }, "evidence": [ { "id": "HGNC:20978", "url": "https://alliancegenome.org/gene/HGNC:20978#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QD13-1", "protein_name": "Trace amine-associated receptor 6", "gene_name": "Taar6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSNSSPPTVLQLCYENVTGSCVKTPYSPGSRVILYAVFGFGAVLAVFGNLMVMISILHFKQLHSPTNFLIASLACADFGVGISVMPFSMVRSIESCWYFGRSFCTFHTCCDVAFCYSSLFHLSFISIDRYIAVTDPLVYPTKFTVSVSGICIGVSWILPLVYSGAVFYTGVYDDGLEELSSALNCVGGCQVVVNQNWVLIDFLSFLIPTLVMIILYGNIFLVARQQAKKIENIGSKTESSSESYKARVARRERKAAKTLGITVVAFMISWLPYSIDSLVDAFMGFITPAYIYEICVWCAYYNSAMNPLIYALFYPWFKKAIKVIMSGQVFKNSSATMNLFSEQI", "length": 345 }, "evidence": [ { "id": "HGNC:20978", "url": "https://alliancegenome.org/gene/HGNC:20978#orthology", "database": "AGR" }, { "id": "RGD:631384", "url": "https://alliancegenome.org/gene/RGD:631384#orthology", "database": "AGR" }, { "id": "MGI:2685074", "url": "https://alliancegenome.org/gene/MGI:2685074#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060414-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060414-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5QNP3-1", "protein_name": "Trace amine associated receptor 15", "gene_name": "taar15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEFQEHHCFSHWNTSCSLDFHLSYVNVFLFLYISAISVLTVCGNLLVIVSITVFKQLHTPTNLLILSLAISDLLVGICLMPVESIRSINSCFYMGKSHCHIFHSIMSIVGSASLMNIMLVAIDRYFAVCNPLLYMSKMTIRKALICVCLGWTVSICYNLVPVNLGNSDPTGAVVVCLRECAVAVSNSWGPADLIVSFIAPCIMMLILYTRILTVALKQAKAISNMTKKNGSQPSRKSEVKATKTLSTIIFVYFICWIPWYVIMLNMEQFNKLPVSISAFLCLFYTNSCINPFIYAISYPWFKRSVKLVVSLRILQTATNQLNLFAEDC", "length": 328 }, "evidence": [ { "id": "MGI:2685074", "url": "https://alliancegenome.org/gene/MGI:2685074#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q923Y5-1", "protein_name": "Trace amine-associated receptor 6", "gene_name": "Taar6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSNSSPPAVLQLCYENVNGSCVKTPYSPGPRVLLYAVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLIASLACADFWVGVSVMPFSMVRSIESCWYFGRSFCTFHTCCDVAFCYSSLFHLSFISIDRYIAVTDPLVYPTKFTVSVSGICISISWILPLAYSGAVFYTGVYADGLEEVSDAVNCVGGCQVVVNQNWVLIDFLSFLIPTLVMIILYGNIFLVARQQAKKIETVGNKAESSSESYKARVARRERKAAKTLGITVVAFMISWLPYSIDSLVDAFMGFITPAYIYEICVWCAYYNSAMNPLIYALFYPWFKKAIKVIMSGQVFKNSSATMNLFSEQI", "length": 345 }, "evidence": [ { "id": "HGNC:20978", "url": "https://alliancegenome.org/gene/HGNC:20978#orthology", "database": "AGR" }, { "id": "RGD:631384", "url": "https://alliancegenome.org/gene/RGD:631384#orthology", "database": "AGR" }, { "id": "MGI:2685074", "url": "https://alliancegenome.org/gene/MGI:2685074#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060414-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060414-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96RI8-1", "protein_name": "Trace amine-associated receptor 6", "gene_name": "TAAR6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI", "length": 345 }, "evidence": [ { "id": "HGNC:20978", "url": "https://alliancegenome.org/gene/HGNC:20978#orthology", "database": "AGR" }, { "id": "RGD:631384", "url": "https://alliancegenome.org/gene/RGD:631384#orthology", "database": "AGR" }, { "id": "MGI:2685074", "url": "https://alliancegenome.org/gene/MGI:2685074#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060414-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060414-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "trace-amine receptor activity", "id": "GO:0001594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001594", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z0U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0U9" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 319, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 296, "end_pos": 298 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z0W1-1", "uniprot_ac": "A0A8M6Z0W1", "uniprot_id": "A0A8M6Z0W1_DANRE", "mass": { "chemical_mass": 38277.0, "monoisotopic_mass": 38277.0 }, "refseq": { "ac": "XP_017213589", "name": "trace amine-associated receptor 13c-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213589" }, "gene_names": [ { "name": "taar19h", "type": "recommended", "evidence": [ { "id": "A0A8M6Z0W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W1" } ] }, { "name": "taar19h", "type": "synonym", "evidence": [ { "id": "XP_017213589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213589" } ] } ], "protein_names": [ { "name": "Trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "A0A8M6Z0W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W1/entry#names_and_taxonomy" } ] }, { "name": "trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "XP_017213589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213589" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017213589.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213589" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0W1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "taar19h", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060414-12", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060414-12", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z0W1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z0W1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "108191518", "url": "https://www.ncbi.nlm.nih.gov/gene/108191518", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108191518", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191518", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z0W1", "url": "https://www.orthodb.org/?gene=A0A8M6Z0W1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249:SF381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249:SF381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213589", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z0W1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z0W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060414-12", "url": "https://zfin.org/ZDB-GENE-060414-12", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDYETEDQETQYCFPDINSSCVKYQRSSHEYNIMYVFFYFLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLVGLIVMPIQAIRLIETCWYFGDTFCGISLILSGVIISASLTNLVLIAVDRYVAVCHPLLYPQKITITNMLLIICLSWIYYSGYNTVLIIYNGYFETSERTDACDGDCLVMIRFSWIVTDLFISFIFPCVIIITLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVKRKSESKAALTLGIIVSVYLLSWIPYCICSVTVNSSTLITILSWTVYTNSGLNPLVYAIFYPWFKKTVKVILTLKIFDPASSLVNIFMEHDL", "length": 335, "header": "tr|A0A8M6Z0W1-1|A0A8M6Z0W1_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=taar19h PE=3 SV=1 CANONICAL=A0A8M6Z0W1-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z0W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W1/entry#A0A8M6Z0W1-1", "sequence": { "sequence": "MDYETEDQETQYCFPDINSSCVKYQRSSHEYNIMYVFFYFLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLVGLIVMPIQAIRLIETCWYFGDTFCGISLILSGVIISASLTNLVLIAVDRYVAVCHPLLYPQKITITNMLLIICLSWIYYSGYNTVLIIYNGYFETSERTDACDGDCLVMIRFSWIVTDLFISFIFPCVIIITLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVKRKSESKAALTLGIIVSVYLLSWIPYCICSVTVNSSTLITILSWTVYTNSGLNPLVYAIFYPWFKKTVKVILTLKIFDPASSLVNIFMEHDL", "length": 335, "header": "tr|A0A8M6Z0W1-1|A0A8M6Z0W1_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=taar19h PE=3 SV=1 CANONICAL=A0A8M6Z0W1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108191518", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191518", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NV51-1", "protein_name": "Trace amine associated receptor 19p", "gene_name": "taar19p", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEHQDTQYCFPNINSSCVKGKRSIQEYNIMYVLFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVTDLLIGLIVMPIQAIRLIETCWYFGDTLCGINLIIIGVIFSASFSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMCICLSWVYYSAYNTGLVINNGYFDTSHRTDVCYGDCSVIMSFSWLVTDLCLSFIFPCVIMITLYLRIFYVVHQQVKVINSLMKGGKCVTKGSVKRKSESKAALTLGIIVLVYLLCYIPYYICTLSVNSSTTITVLEWTVYTNSGLNPLVYALFYHWFKKTVKLILTLKIFHPESSLINVFTVHEL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z0V5-1", "protein_name": "Trace amine-associated receptor 13c", "gene_name": "taar19t", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDADTVYIKGQKGEQNKLLTGGDSLMAYETEDQETQYCFPDINSSCVKEKRSIQEYNIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLILMPVEAIRLIETCWYFGETFCVLYLILIGLIFSATLSCLVLIAVDRYVAVCHPLLYPQKITITNMLMSICLSWVCYSAYNTAFAFNNGYLNSSHRRDVCYGQCFIMMTFSWTVTDLSMCFIFPCVIMITLYSRIFYVVHQQVKVINSLMKGGKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTITVLMWTVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 361 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1I0-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKGRHSSHGYIIIYLFVSLLSVWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLIIGLFVIPIQAIKLIETCWYFGDTFCGLYLFLIFELLSASLSNLVLIAVDRYVAVCHPLLYPQKITITKTLMSICLSWVCYSAYNTALIINNRYSETSHRTDECYGRCFIVMSFSWLVADLVMSFIFPCLIMITLYLMIFYVVHQQVKVMNSLMKGGKCVTEGSVKRKSESKAALTLGIIVTIYLLCYIPYYICSLVVNSSTAIHVMSWTVYVNSGMNPLVYALFYPWFKKTAKIIFTLKIFQPASSLINIFTELDM", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z335-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19r", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEHQETQYCFPNINSSCVKGRRYRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILFLAVNDLLIGLIVLPVEAIRLIERCWYFGETFCFLYLILIVLIFSASLSYLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNIAFVINNRNLNSSQKTDVCYGQCLIMMSFSWTIIDLSICFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGAKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTINVLMWNVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z339-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "si:ch211-139n6.11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKGKRSRHEYIIMYVFFLLLSAWTVILNLLVIISISHFKKLHSPTNLLILSLSVADLLVGLIVIPIEAIKQIETCWYFGATFCGINLIIIGVIFSASFSNLVLIAVDRYVAVCHPLLYPQKITTAKMLMSICLSWLYYSAYNAGLVVNNGYFDTAHRTDVCYGDCTVIMSFGWIVIDLFMSFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKCLTEISVKRKSESKAALTLGIIVLVYLFSYIPYYICTLSVNSVTTNNVLGWTVYANSGLNPLVYALFYPWFKKTAKIILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z8I1-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19s", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKGRRYRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILFLAVNDLLIGLIVLPVEAIRLIERCWYFGETFCFLYLILIVLIFSASLSYLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNIAFVINNRNLNSSQKTDVCYGQCLIMMSFSWTVIDLSICFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTINVLMWNVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z8X3-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "si:ch211-238p8.31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKEKRSSHEYNIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVTDMFVGLIVIPVKAIKLIERCWYFGDTFCGLFIIIIGVIFSASLSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMSICLSWLYYSAYNTALIINNGYFDTSNRTDMCNGECPVMVSFSWILTDLSMCFIFPCLIMITLYSRIFFAVHQQVKVINSLMKRDKCVMKGSVKRKSERKAALTLGIIVTIYLLCYIPYYICSLVIISSTALNVLTWTMYANSGLNPLVYALFYPWFKKTAKLILTLKIFQPASSLVNIFTENEL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCQ8-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKEQHSTNGYIIYLFVSFLSAWTVFLNLLVIISISHFKKLHTPTNMIVLSLAVADLLIGLIVMPVEAVKLIETCWYFGDTFCGFTLILIGVIPSASLGNLVLIAVDRYAAVCHPLLYPQKITMANMLMSICLSWVYYSTYITTLVIYNRYFDTSHRTDECYGQCLVMMSFSWILTDLFVCFVFPCVLIITLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVKRKSESKAALTLGIIVSVYLLCWIPYYICTLTVNSSTVLSVLTWVLYANSGLNPLVYALFYPWFKKTVKHILTMTICQLASSLVNIFTEHEL", "length": 334 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QD04-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "Taar9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSDFSPEPPMELCYENVNGSCIKSSYAPWPRAILYGVLGLGALLAVFGNLLVIIAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVESCWYFGESYCKFHTCFDTSFCFASLFHLCCISIDRYIAVTDPLTYPTKFTVSVSGLCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKYQARKIEGTANQAQASSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSTTNLFSEEAGAG", "length": 348 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060414-12", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060414-12#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5QD16-1", "protein_name": "Trace amine-associated receptor 3", "gene_name": "Taar3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLIYIPEDLSSCPKFGNKSCPPTNRSFRVRMIMYLFMTGAMVITIFGNLVIIISISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSMVRSVESCWYFGDSFCKFHASFDMMLSLTSIFHLCSIAIDRFYAVCDPLHYTTTMTVSMIKRLLAFCWAAPALFSFGLVLSEANVSGMQSYEILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSRRHARALSDMPANTKGAVGKNLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPIIVLDLLVWLGYFNSTCNPLIHGFFYPWFRKALQFIVSGKIFRSNSDTANLFPEAH", "length": 343 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5QD24-1", "protein_name": "Trace amine-associated receptor 3", "gene_name": "Taar3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLIYIPEDLSSCPKFGNKSCPPTNRSFRVRLIMYLLMTGAMVITIFGNLVIIISISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSMVRSVESCWYFGDSFCKFHASFDMMLSLTSIFHLCSIAIDRFYAVCAPLHYTTTMTASMIKRLLFFCWAAPALFSFGLVLSEANVSGMQSYEILIACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSRRHARALGNMPENTKGAGRNLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPIIVLDLLVWLGYFNSTCNPLIHGFFYPWFRKALEHIVSGKIFRSNSDTANLFPEAH", "length": 342 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060414-12", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060414-12#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q923Y6-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "Taar9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELCYENVNGSCIKSSYSPWPRAILYAVLGLGALLAVFGNLLVITAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVEGCWYFGDTYCKFHTCFDTSFCFASLFHLCCISIDRYVAVTDPLTYPTKFTISVSGVCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKQQARKIEGSANQPQASSESYKERVARRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSRTNLFSEEAGAG", "length": 338 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96RI9-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "TAAR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD", "length": 348 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060414-12", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060414-12#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9P1P4-1", "protein_name": "Putative trace amine-associated receptor 3", "gene_name": "TAAR3P", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLTYIPEDLSSCPKFVNKILSSHQPLFSCPGDNVFGYDWSHDYPLFGNLVIMVSISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSIMRSVESCWYFGDGFCKFHTSFDMMLRLTSIFHLCSIAIDRFYAVCYPLHYTTKMTNSTIKQLLAFCWSVPALFSFGLVLSEADVSGMQSYKILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSKQHARVISHVPENTKGAVKKHLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPILILDLLVWLRYFNSTCNPLIHGFFNPWFQKAFKYIVSGKIFSSHSETANLFPEAH", "length": 343 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0W1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0W1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "trace-amine receptor activity", "id": "GO:0001594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001594", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0W1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z0W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 300, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 277, "end_pos": 279 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z0W6-1", "uniprot_ac": "A0A8M6Z0W6", "uniprot_id": "A0A8M6Z0W6_DANRE", "mass": { "chemical_mass": 38200.0, "monoisotopic_mass": 38200.0 }, "refseq": { "ac": "XP_017213594", "name": "trace amine-associated receptor 13c-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213594" }, "gene_names": [ { "name": "taar19j", "type": "recommended", "evidence": [ { "id": "A0A8M6Z0W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W6" } ] }, { "name": "taar19j", "type": "synonym", "evidence": [ { "id": "XP_017213594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213594" } ] } ], "protein_names": [ { "name": "Trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "A0A8M6Z0W6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W6/entry#names_and_taxonomy" } ] }, { "name": "trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "XP_017213594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213594" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017213594.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213594", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213594" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0W6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "taar19j", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0W6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091116-24", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-24", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z0W6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z0W6", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15055", "url": 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0Z1/entry#names_and_taxonomy" } ] }, { "name": "cyclin-dependent kinase 2-associated protein 1", "type": "synonym", "evidence": [ { "id": "XP_017213656", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213656" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213656", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213656" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z0Z1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0Z1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cdk2ap1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0Z1", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z0Z1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z0Z1", "database": "AlphaFoldDB", "categories": [] }, { "id": "108191561", "url": "https://www.ncbi.nlm.nih.gov/gene/108191561", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR017266", "url": 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protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206762" }, "gene_names": [ { "name": "LOC100329885", "type": "recommended", "evidence": [ { "id": "A0A8M6Z108", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108" } ] }, { "name": "LOC100329885", "type": "synonym", "evidence": [ { "id": "XP_017206762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206762" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M6Z108", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017206762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206762" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017206762.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017206762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206762" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z108", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z108", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100329885", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z108", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z108", "database": "AlphaFoldDB", "categories": [] }, { "id": "100329885", "url": "https://www.ncbi.nlm.nih.gov/gene/100329885", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100329885", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100329885", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z108", "url": "https://www.orthodb.org/?gene=A0A8M6Z108", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017206762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206762", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z108", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z108-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEKKKQRARLNEEEEDFKTLNIKDRELCGRGGGLMDKSKEKKTCKRKREHLCLLCGKSFTTAGHLKIHHMIHTGEKPHKCSYCEKSFTQPGTLKIHERIHTGEKSYHCTQCGHDFISASVLKLHMRVHTNEKPYACPFCGKTFTRFDHCKRHQKTHTDNRNHVCLECGMSFNRADCLKQHQRVHTGEKPYKCSYCERSFSQSGNLTLHERIHTGERPYYCPPCDRGFIDCKRLDNHIKKHHKSSR", "length": 245, "header": "tr|A0A8M6Z108-1|A0A8M6Z108_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC100329885 PE=4 SV=2 CANONICAL=A0A8M6Z108-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z108-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108/entry#A0A8M6Z108-1", "sequence": { "sequence": "MEKKKQRARLNEEEEDFKTLNIKDRELCGRGGGLMDKSKEKKTCKRKREHLCLLCGKSFTTAGHLKIHHMIHTGEKPHKCSYCEKSFTQPGTLKIHERIHTGEKSYHCTQCGHDFISASVLKLHMRVHTNEKPYACPFCGKTFTRFDHCKRHQKTHTDNRNHVCLECGMSFNRADCLKQHQRVHTGEKPYKCSYCERSFSQSGNLTLHERIHTGERPYYCPPCDRGFIDCKRLDNHIKKHHKSSR", "length": 245, "header": "tr|A0A8M6Z108-1|A0A8M6Z108_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC100329885 PE=4 SV=2 CANONICAL=A0A8M6Z108-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100329885", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100329885", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z108", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z108", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z108", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z108", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z108", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z108", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z108", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z108", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z108", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z108" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 77, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 204, "end_pos": 206 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z146-1", "uniprot_ac": "A0A8M6Z146", "uniprot_id": "A0A8M6Z146_DANRE", "mass": { "chemical_mass": 86152.0, "monoisotopic_mass": 86152.0 }, "refseq": { "ac": "XP_017213771", "name": "inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213771" }, "gene_names": [ { "name": "naaladl2", "type": "recommended", "evidence": [ { "id": "A0A8M6Z146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z146" } ] }, { "name": "naaladl2", "type": "synonym", "evidence": [ { "id": "XP_017213771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213771" } ] } ], "protein_names": [ { "name": "Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z146/entry#names_and_taxonomy" } ] }, { "name": "inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017213771", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213771" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017213771.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213771", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213771" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z146", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z146" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "naaladl2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z146", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z146", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z146", "database": "AlphaFoldDB", "categories": [] }, { "id": "101885785", "url": "https://www.ncbi.nlm.nih.gov/gene/101885785", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039373", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039373", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885785", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885785", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z146", "url": "https://www.orthodb.org/?gene=A0A8M6Z146", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10404:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10404:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04389", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213771", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213771", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z146", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z146", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z146-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z146-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GRV2", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GRV2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GRY2", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GRY2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVDTQEFHSNPALQVTDMAYRKVRAGHGSLRVRDLENEELHTASLELEWDMEKELEEPGLDRFQLECVEHQPVSSSSGGTMDPDLEPIQPSVSPHGRFERLQEDPNYVTRFSRTVPKGQRQNWTCVAKYLLVGVCVFAAGLLIGRYTFSRVQVKEEPIADTDVLEKIGLGITAEKIQALQRDFDSLSDLTEESKVKYIAQRWKEIGLKDVQVTKHMALLSHPGPVLSTIVDKSGNQCYLPSGARCEKQFTTTSEAFAFAAYSAVGNIVAEVVDVQYGSPEDLRHVQASTNVTNKIALLKLGGAPLLYKLSLLVELGFAGCLLYVDPCDGSFGYKTFGVTLNPGGNPSFPKDPRVVGRDNLYNLTSLLVQPISASLAKMLLSASAMGQGRPCVPMIMPPTSARKIINLTIENQVSFKAVHNVMGYLKGKTNPDRYVLVGSRHGSWYEGALADWGNGSAVMTQIIAFMMAQTRVGWRPDRTIVFCSWGGTSLGNIGSYEWGKENALVLQSRAVAYVSLHSPMTNSGSLQATASPSLLQLAGEIQKRHSMSCSRGAGCSVSSVSSLQTPGDANFFSNQLGVPTVEFTYAEVPKTERALFLSEAFFPPESSLGETLDPAFKLHETIAKITTEAILRLATDPVLPFCPLDVALNVQSKLKDETLRGLDLLNVAASLRENSTFFQSEVMRPANDPKERDPAHVRMLNDVLRDLEKSFLIPTPPAGFYRNILYCLSRQTPRFSILKDALEVSWHNSISHSQNLVYSAISSAQKLVQSGLDLFENENDNLK", "length": 783, "header": "tr|A0A8M6Z146-1|A0A8M6Z146_DANRE Isoform 1 of Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X1 OS=Danio rerio OX=7955 GN=naaladl2 PE=3 SV=2 CANONICAL=A0A8M6Z146-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z146-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z146/entry#A0A8M6Z146-1", "sequence": { "sequence": "MVDTQEFHSNPALQVTDMAYRKVRAGHGSLRVRDLENEELHTASLELEWDMEKELEEPGLDRFQLECVEHQPVSSSSGGTMDPDLEPIQPSVSPHGRFERLQEDPNYVTRFSRTVPKGQRQNWTCVAKYLLVGVCVFAAGLLIGRYTFSRVQVKEEPIADTDVLEKIGLGITAEKIQALQRDFDSLSDLTEESKVKYIAQRWKEIGLKDVQVTKHMALLSHPGPVLSTIVDKSGNQCYLPSGARCEKQFTTTSEAFAFAAYSAVGNIVAEVVDVQYGSPEDLRHVQASTNVTNKIALLKLGGAPLLYKLSLLVELGFAGCLLYVDPCDGSFGYKTFGVTLNPGGNPSFPKDPRVVGRDNLYNLTSLLVQPISASLAKMLLSASAMGQGRPCVPMIMPPTSARKIINLTIENQVSFKAVHNVMGYLKGKTNPDRYVLVGSRHGSWYEGALADWGNGSAVMTQIIAFMMAQTRVGWRPDRTIVFCSWGGTSLGNIGSYEWGKENALVLQSRAVAYVSLHSPMTNSGSLQATASPSLLQLAGEIQKRHSMSCSRGAGCSVSSVSSLQTPGDANFFSNQLGVPTVEFTYAEVPKTERALFLSEAFFPPESSLGETLDPAFKLHETIAKITTEAILRLATDPVLPFCPLDVALNVQSKLKDETLRGLDLLNVAASLRENSTFFQSEVMRPANDPKERDPAHVRMLNDVLRDLEKSFLIPTPPAGFYRNILYCLSRQTPRFSILKDALEVSWHNSISHSQNLVYSAISSAQKLVQSGLDLFENENDNLK", "length": 783, "header": "tr|A0A8M6Z146-1|A0A8M6Z146_DANRE Isoform 1 of Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X1 OS=Danio rerio OX=7955 GN=naaladl2 PE=3 SV=2 CANONICAL=A0A8M6Z146-1" }, "locus": {} }, { "isoform_ac": "A0AC58GRV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z146/entry#A0AC58GRV2-1", "sequence": { "sequence": "MAYRKVRAGHGSLRVRDLENEELHTASLELEWDMEKELEEPGLDRFQLECVEHQPVSSSSGGTMDPDLEPIQPSVSPHGRFERLQEDPNYVTRFSRTVPKGQRQNWTCVAKYLLVGVCVFAAGLLIGRYTFSRVQVKEEPIADTDVLEKIGLGITAEKIQALQRDFDSLSDLTEESKVKYIAQRWKEIGLKDVQVTKHMALLSHPGPVLSTIVDKSGNQCYLPSGARCEKQFTTTSEAFAFAAYSAVGNIVAEVVDVQYGSPEDLRHVQASTNVTNKIALLKLGGAPLLYKLSLLVELGFAGCLLYVDPCDGSFGYKTFGVTLNPGGNPSFPKDPRVVGRDNLYNLTSLLVQPISASLAKMLLSASAMGQGRPCVPMIMPPTSARKIINLTIENQVSFKAVHNVMGYLKGKTNPDRYVLVGSRHGSWYEGALADWGNGSAVMTQIIAFMMAQTRVGWRPDRTIVFCSWGGTSLGNIGSYEWGKENALVLQSRAVAYVSLHSPMTNSGSLQATASPSLLQLAGEIQKRHSMSCSRGAGCSVSSVSSLQTPGDANFFSNQLGVPTVEFTYAEVPKTERALFLSEAFFPPESSLGETLDPAFKLHETIAKITTEAILRLATDPVLPFCPLDVALNVQSKLKDETLRGLDLLNVAASLRENSTFFQSEVMRPANDPKERDPAHVRMLNDVLRDLEKSFLIPTPPAGFYRNILYCLSRQTPRFSILKDALEVSWHNSISHSQNLVYSAISSAQKLVQSGLDLFENENDNLK", "length": 766, "header": "tr|A0AC58GRV2-1|A0AC58GRV2_DANRE Computationally mapped isoform of Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X2 OS=Danio rerio OX=7955 GN=naaladl2 PE=3 SV=1 CANONICAL=A0A8M6Z146-1" }, "locus": {} }, { "isoform_ac": "A0AC58GRY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z146/entry#A0AC58GRY2-1", "sequence": { "sequence": "MLLSASAMGQGRPCVPMIMPPTSARKIINLTIENQVSFKAVHNVMGYLKGKTNPDRYVLVGSRHGSWYEGALADWGNGSAVMTQIIAFMMAQTRVGWRPDRTIVFCSWGGTSLGNIGSYEWGKENALVLQSRAVAYVSLHSPMTNSGSLQATASPSLLQLAGEIQKRHSMSCSRGAGCSVSSVSSLQTPGDANFFSNQLGVPTVEFTYAEVPKTERALFLSEAFFPPESSLGETLDPAFKLHETIAKITTEAILRLATDPVLPFCPLDVALNVQSKLKDETLRGLDLLNVAASLRENSTFFQSEVMRPANDPKERDPAHVRMLNDVLRDLEKSFLIPTPPAGFYRNILYCLSRQTPRFSILKDALEVSWHNSISHSQNLVYSAISSAQKLVQSGLDLFENENDNLK", "length": 406, "header": "tr|A0AC58GRY2-1|A0AC58GRY2_DANRE Computationally mapped isoform of Inactive N-acetylated-alpha-linked acidic dipeptidase-like protein 2 isoform X3 OS=Danio rerio OX=7955 GN=naaladl2 PE=3 SV=1 CANONICAL=A0A8M6Z146-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885785", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885785", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z146", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z146" }, { "id": "PF04389", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04389" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M28", "eco_id": "ECO_0000259", "start_pos": 420, "end_pos": 583, "start_aa": "Asn", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 362, "end_pos": 364 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 674, "end_pos": 676 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z154-1", "uniprot_ac": "A0A8M6Z154", "uniprot_id": "A0A8M6Z154_DANRE", "mass": { "chemical_mass": 154852.0, "monoisotopic_mass": 154852.0 }, "refseq": { "ac": "XP_017213319", "name": "uncharacterized protein ankrd50l", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213319" }, "gene_names": [ { "name": "ankrd50l", "type": "recommended", "evidence": [ { "id": "A0A8M6Z154", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z154" } ] }, { "name": "ankrd50l", "type": "synonym", "evidence": [ { "id": "XP_017213319", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213319" } ] } ], "protein_names": [ { "name": "Uncharacterized protein ankrd50l", "type": "synonym", "evidence": [ { "id": "A0A8M6Z154", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z154/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein ankrd50l", "type": "synonym", "evidence": [ { "id": "XP_017213319", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213319" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213319", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213319" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z154", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z154" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ankrd50l", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z154", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041008-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041008-117", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "449857", "url": "https://www.ncbi.nlm.nih.gov/gene/449857", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:449857", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449857", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WMLWAGV", "url": "https://omabrowser.org/oma/group/WMLWAGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z154", "url": "https://www.orthodb.org/?gene=A0A8M6Z154", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198:SF165", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198:SF165", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24883", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24883", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25521", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25521", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213319", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213319", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z154", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z154", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z154-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z154-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041008-117", "url": "https://zfin.org/ZDB-GENE-041008-117", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVRPGSSPEGQMRSMLPSLLRGRRFYCREWALEKLQRCLEARDANKGVEGSNRVSPGVLVTGGPGTGKTALCTELVWPQSETCKAAGLASRCLAWHYCQREDAGSVEVWRFVLALVEQLKESPLLGPNYVKVISSASVATVLEPLHCQRAPDETFKRAVLEPLLSLTPPAHSVFIVVDSVDSGCCGGNGVGEGSISGSAGTPSSSIAELLLKHIQLFPPWILLVCSARRQNKAVCKMFSGFRKLCLDDLRKPATVRDVQQYILRRLDQDGALRRQLTPETAEMLNLLHIKSGGCFLFLERVMDGVANGLVGLREIRDIPGTLNGLYLWLCQRLFPRRLFVHIRPLLNILLASQQPLTAEDLYTIAKSRDCYLGIRDFQAQMGALASLFVDGPEGSKLLFHSSFAEWLTDVKYCTQKFLCCVKDGHLSMAMSLSLRASSLSTEETCQLAHHLLNSGVHEGEPALLALWLLWTGVPALNGTRKDCPSNVLSTSHTPVLVQQDVLQLLMKSGIYPSSCSPDKSSSVGVHCVGGGSRIVRRALQREESVRALLDSGVSVNRTDPLDGRTLLAAAAHAGLVDVAALLLCHGADPSLTDNQGQTALTLAAKQGHVGVLQVLLDWVQEQRSKGSAAHTLLEHADSEGWTALRSAAWGGHKEAVRRLLEAGAEVDGCDSDGRTALRAAAWGGHEEILLTLLGHGAEVDHSDREGRTPLIAAAYMGHKETVEILLDAGADLNLADGDGRTALSVAALCVPSSAGGRGHGEVVSLLLERGADPEHKDRDGMTPLLLASYEGHEEVVELLLEAGADVDESSGAHPSSITPLLAAAAMGHTRTVNRMLFWGAAVDGIDGEGRTALCLAAAKGSIEVVRALLDRGLDENHKDDLGWTPLHAAACEGHKSVCAILTERGSMARVGELDVEGRSPLILAAQEGHCSTVRLLLDRKSPIDHRAYDGHSALSAAALQGHRDIVELLMRRGADTDVRDAEGRPLLYLLVLEGRLDMATLLIEKGGVPLESKDAEGRTALHVAAWRGDLEGTELLLKYGADPNARDLDGRPPLHSVAWRGHTAAGRLLLRAKGLNVDLACKQQGATALSVAAQEGHSEIVVMLLEKGANPDHVDRYGRTPVKVAGKQSHFTIVRLLESYGAKPFSGLIPFTPSGAPNASYLSGIVKTHPSISSGEVAADRVPTVSSPSSTSASCSPASTAERFHSMPASQTSSSTCHSLATVQTVPADSLNFIQQIQQHSLPRSRSRPSTLPLPGSNPTSLQGRASRHNHTAAPKCSPTHEQCSYTELQDLEKPLKGLRLSGDGNYLLKAKSPYIIEDVMEKSLKQTGGIDLKWNSIMASLGVMPNQEGLHRQTKIRQSPPLGYPPFHLQSHAQQGDWGGLQKTLMSPTIDLSAVSPHSALPDESLFNMTTDPHLNLKQAIKLQFEGPTSAALYKRETPL", "length": 1441, "header": "tr|A0A8M6Z154-1|A0A8M6Z154_DANRE Isoform 1 of Uncharacterized protein ankrd50l OS=Danio rerio OX=7955 GN=ankrd50l PE=4 SV=1 CANONICAL=A0A8M6Z154-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z154-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z154/entry#A0A8M6Z154-1", "sequence": { "sequence": "MVRPGSSPEGQMRSMLPSLLRGRRFYCREWALEKLQRCLEARDANKGVEGSNRVSPGVLVTGGPGTGKTALCTELVWPQSETCKAAGLASRCLAWHYCQREDAGSVEVWRFVLALVEQLKESPLLGPNYVKVISSASVATVLEPLHCQRAPDETFKRAVLEPLLSLTPPAHSVFIVVDSVDSGCCGGNGVGEGSISGSAGTPSSSIAELLLKHIQLFPPWILLVCSARRQNKAVCKMFSGFRKLCLDDLRKPATVRDVQQYILRRLDQDGALRRQLTPETAEMLNLLHIKSGGCFLFLERVMDGVANGLVGLREIRDIPGTLNGLYLWLCQRLFPRRLFVHIRPLLNILLASQQPLTAEDLYTIAKSRDCYLGIRDFQAQMGALASLFVDGPEGSKLLFHSSFAEWLTDVKYCTQKFLCCVKDGHLSMAMSLSLRASSLSTEETCQLAHHLLNSGVHEGEPALLALWLLWTGVPALNGTRKDCPSNVLSTSHTPVLVQQDVLQLLMKSGIYPSSCSPDKSSSVGVHCVGGGSRIVRRALQREESVRALLDSGVSVNRTDPLDGRTLLAAAAHAGLVDVAALLLCHGADPSLTDNQGQTALTLAAKQGHVGVLQVLLDWVQEQRSKGSAAHTLLEHADSEGWTALRSAAWGGHKEAVRRLLEAGAEVDGCDSDGRTALRAAAWGGHEEILLTLLGHGAEVDHSDREGRTPLIAAAYMGHKETVEILLDAGADLNLADGDGRTALSVAALCVPSSAGGRGHGEVVSLLLERGADPEHKDRDGMTPLLLASYEGHEEVVELLLEAGADVDESSGAHPSSITPLLAAAAMGHTRTVNRMLFWGAAVDGIDGEGRTALCLAAAKGSIEVVRALLDRGLDENHKDDLGWTPLHAAACEGHKSVCAILTERGSMARVGELDVEGRSPLILAAQEGHCSTVRLLLDRKSPIDHRAYDGHSALSAAALQGHRDIVELLMRRGADTDVRDAEGRPLLYLLVLEGRLDMATLLIEKGGVPLESKDAEGRTALHVAAWRGDLEGTELLLKYGADPNARDLDGRPPLHSVAWRGHTAAGRLLLRAKGLNVDLACKQQGATALSVAAQEGHSEIVVMLLEKGANPDHVDRYGRTPVKVAGKQSHFTIVRLLESYGAKPFSGLIPFTPSGAPNASYLSGIVKTHPSISSGEVAADRVPTVSSPSSTSASCSPASTAERFHSMPASQTSSSTCHSLATVQTVPADSLNFIQQIQQHSLPRSRSRPSTLPLPGSNPTSLQGRASRHNHTAAPKCSPTHEQCSYTELQDLEKPLKGLRLSGDGNYLLKAKSPYIIEDVMEKSLKQTGGIDLKWNSIMASLGVMPNQEGLHRQTKIRQSPPLGYPPFHLQSHAQQGDWGGLQKTLMSPTIDLSAVSPHSALPDESLFNMTTDPHLNLKQAIKLQFEGPTSAALYKRETPL", "length": 1441, "header": "tr|A0A8M6Z154-1|A0A8M6Z154_DANRE Isoform 1 of Uncharacterized protein ankrd50l OS=Danio rerio OX=7955 GN=ankrd50l PE=4 SV=1 CANONICAL=A0A8M6Z154-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1430, "start_aa": "Thr", "end_pos": 1430, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1430", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 201, "start_aa": "Thr", "end_pos": 201, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr201", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:449857", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449857", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LWB9-1", "protein_name": "Ankyrin repeat domain containing 50", "gene_name": "Ankrd50", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNPWEEKVCKMAQTSLLQGKQFYCREWVFHKLQHCLQEKSSRCFSAANAQSLVGDAGNNASALSGKGASWGVLLVGGPGSGKTALCTELLWPSSPASLQRGLHRQALAFHFCKAQDSDTLCVGGFIRGLVAQICQSGLLQGYEDKLRDPAVQSLLEPGECERNPAEAFKRCVLLPLLGMKPPPQSLYLLVDSVDEGCNVVEGEQTSPNLSGTVAELLAGHHEFFPPWLLLLCSARKQSRAVTKMFTGFRKISLDDLRKAYIVKDVQQYILHRLDQEEALRQHLTKETAETLNQLHIKSSGCFLYLERVLDGVVENFIMLREIRDIPGTLNGLYLWLCQRLFVRKQFAKVQPILNVILAACRPLTMTELYHAVWTKNMSLTLEDFQRKLDVLSKLLVDGLGSTKILFHHSFAEWLLDVKHCTQKYLCNAAEGHRMLAMSYTCQARNLTPLEAQEFALHLINSNLQLEPAELALWMIWNGTPVKDSLSTLIPKEQEVLQLLIRAGAHVNSEDDRTSCIVRQALEREDSIRTLLDSGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDTHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDESHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNYKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHVEMVRVLIACHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHVDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLNGCSPSPVHTMEQKPPQSTPSKMQSLTIRSNSSGGTGGGDLQPSLRGLPNGPAHAFSSPSESPDSTVDRQKSSLSNNSLKSSKNSSLRTTSSTATAQTVPIDSFHSLSFTEQIQQHSLPRSRSRQSVVSPSSTTQSLGHSHNSPSSEFEWSQVKPSLKSTKSNKGGKSENSSKSGSAGKKAKQNNSSQPKVLEYEMTQFDKRGPVAKSGSSPPKQMPAESQCKIMVPSSQDSNRAQPQFLIHQQGGEQKRRNGIMTNPNYHLQSNQVFLGRVSVPRTLQERGHQEVLEGFPPSETELNLKQALKLQIEGSDPSFNYKKETPL", "length": 1427 }, "evidence": [ { "id": "RGD:1311665", "url": "https://alliancegenome.org/gene/RGD:1311665#orthology", "database": "AGR" }, { "id": "HGNC:29223", "url": "https://alliancegenome.org/gene/HGNC:29223#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041008-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041008-117#orthology", "database": "AGR" }, { "id": "FB:FBgn0039590", "url": "https://alliancegenome.org/gene/FB:FBgn0039590#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ULJ7-1", "protein_name": "Ankyrin repeat domain-containing protein 50", "gene_name": "ANKRD50", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTNPWEEKVCKMAQTSLLQGKQFYCREWVFHKLQHCLQEKSNCCNSAVNAPSLVMNSGNNASGVSGKGAAWGVLLVGGPGSGKTALCTELLWPSSPASLQRGLHRQALAFHFCKAQDSDTLCVGGFIRGLVAQICRSGLLQGYEDKLRDPAVQSLLQPGECERNPAEAFKRCVLLPLLGMKPPQQSLYLLVDSVDEGCNITEGEQTSTSLSGTVAALLAGHHEFFPPWLLLLCSARKQSKAVTKMFTGFRKISLDDLRKAYIVKDVQQYILHRLDQEEALRQHLTKETAEMLNQLHIKSSGCFLYLERVLDGVVENFIMLREIRDIPGTLNGLYLWLCQRLFVRKQFAKVQPILNVILAACRPLTITELYHAVWTKNMSLTLEDFQRKLDILSKLLVDGLGNTKILFHYSFAEWLLDVKHCTQKYLCNAAEGHRMLAMSYTCQAKNLTPLEAQEFALHLINSNLQLETAELALWMIWNGTPVRDSLSTLIPKEQEVLQLLVKAGAHVNSEDDRTSCIVRQALEREDSIRTLLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGHSQIIKLLEKYGASSLNGCSPSPVHTMEQKPLQSLSSKVQSLTIKSNSSGSTGGGDMQPSLRGLPNGPTHAFSSPSESPDSTVDRQKSSLSNNSLKSSKNSSLRTTSSTATAQTVPIDSFHNLSFTEQIQQHSLPRSRSRQSIVSPSSTTQSLGQSHNSPSSEFEWSQVKPSLKSTKASKGGKSENSAKSGSAGKKAKQSNSSQPKVLEYEMTQFDRRGPIAKSGTAAPPKQMPAESQCKIMIPSAQQEIGRSQQQFLIHQQSGEQKKRNGIMTNPNYHLQSNQVFLGRVSVPRTMQDRGHQEVLEGYPSSETELSLKQALKLQIEGSDPSFNYKKETPL", "length": 1429 }, "evidence": [ { "id": "RGD:1311665", "url": "https://alliancegenome.org/gene/RGD:1311665#orthology", "database": "AGR" }, { "id": "HGNC:29223", "url": "https://alliancegenome.org/gene/HGNC:29223#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041008-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041008-117#orthology", "database": "AGR" }, { "id": "FB:FBgn0039590", "url": "https://alliancegenome.org/gene/FB:FBgn0039590#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VAU5-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG10011", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKHTDNDNLRNDIYENLPCQAMYNDSVRKMQQQKSSTQTVSSNHNPNANSIGNCDSTSVINKNHPPPVNNMPKEMLYATPLRKSDRYKSGDRTRHVATGNAETKLFNFRDSNRLASARNGNPVQVTDLDADEDDAQGDGVDGCGSTSALVGGSKYSSQPSAGTANQHLEDRRILNFLKDTTQLQKKLEITGRDCPNASFSNLAREEHFANLVQQNFPQDVAHHANGETNGGSAPEEDGQEAAGGLKTQPTEDTDGNLEALMQRKVSPDKEVNGLVHSAGVEPNNRIVSTVYIHREWVLKKIALCLEQRTAGKKSGPVALGGAASSSYVSARAKAAAISSSSYNGCLVLGSNGSGKTSICQAIMKGNSGTKGILNRKLLACYLIESQNPECHSLSLFMRKIVLQLLSHASLISRDESQRIIDEGFSFLRDEAQQQEFKLDEAMNNISLSENAEELLIEELKRGASECDTKELDNFQSQRTSTVNKAARTTLTRQQSEPAPLQAMDAVNSDEKTGSNYGTHPPKRASRERGDTEQDKDMGSEKEQKQSQEPKETPKSSPAKSKSKIPVKRGRSGSGVLSPSKLATISNGGQSIQQGGGEDIADLNTDQEKHEIEAAIKDDKVEEPQANNEDKKEDKPEADKELNDQLKEELDKSSQEPKEEETKEEATADSSAEPLIDFTESNVNGKQEEPQLKPPVPGEKPRISTNTLPPPLPKTKSCRTIIADGYYELLLSNPEILECLSVDNIEKNPDECFKKAFLFPLLELTPPKTALLLLIDSIDENYINEGNLISTLKGGRGTVTNHKSRNVAELLSNHIHLFPKWLFLVCTTKKQTKQITKMFTGFKKITLDDLRKSHVVKDVQEYIINRLNSDFKDSIMLTKEIIESLHQLYIKSNGCILYLEKVLHGIKDNFFSFREIKLIPCTLNGLYLYICQKSFNKKQYMKIRPLLNVLLASSGYVDKLFLFNCLRTHNYTIDCQEFEKRLQLMRNILAYDSNAQRLKIFHNSFADWLVDVKFATKKFICDVNEGHVMISMYYLLVADTLCANTVRRFAYHLIRSGEYLTSRHVDLDLILMLLESRLNLSDCFYTNQMNCCAQCEHDFKYDVNFLPKTRAMLERFLASELSEPFAQFLCDFFKPSLPTDAKMLKLLIETGINNAESQNSCESSLMSPELSEKSQNIDFELADLLLSSEKSCLMETQRAGSPSEHSEPPAESQDENASSTLHQLSDSHHIELHKGKALIHILANDGNHQLLERALNACKSPIDLEIEDYNGQTALNIAARNGHLEVVKLLLSFSQPCNDGTGRMKRVDVNHADRDGWTPLRSASWGGHSEVVRLLIAQPACKIDLADKEGRTALRAAAWSGHEDILKLLIESGADVNSVDRQGRTSLIAASYMGHYDIVEILLENGANVNHLDLDGRSALCVAALCGSSGYSKVISTLLDHGANTDQLDNDGMSPLLVSSFEGNAEVCELLLENAADPDLADFMGRTPLWAACTAGHATVVKLLLFWGCGIDCMDSEGRTVLSIGAAQGNVETVRQLLDRGLDETHRDNAGWTPLHYAAFEGFHEVCLQLLESGAKIDECDNEGKTALHLAAQEGRLHCVQALLDIHSSFVDQKAHDGKTAFRLACLEGHMDTVEFLLKFCCDVNSKDADSRTTLYILALENKLEIVKYLLDMTNVDVNIPDSEGRTALHVAAWQGHADMVKTLIEAGADVNSMDLEARTPLHSCAWQGNHDVMNILLYYGALADHACKQGATALGISAQEGHEKCVIALLQFGANPYKSDHCGRTPIKLAAKSSRTSILKIFESYTKNEASNPNEPKFHAHASMLRSPDQPPALPLHQNLAPYPAHASASSVCSAATTATVHNGSHLHVLNASSSTHSSNNFYQNTMQSDTSSLHKRKSVISSQSTGSSNDQAPLTFTQQLQRQSKLSSRNNLMVNSKHASSSGAAGHKSSGGGGGAQRHSQVLPDLSEHQLASNMTNEADMYDMECMSPLYATPPHSPSSELSSPGQLPGLNAFVDDERAGTSSGGGAKLPDNHFARDTHMRIILGNLKENQPSSSGKSKRSGVSSNPAMRLIRSRFDAASQLIRRTNNILSSSSNQGSSSIGVKSGTFQWRKESQM", "length": 2119 }, "evidence": [ { "id": "RGD:1311665", "url": "https://alliancegenome.org/gene/RGD:1311665#orthology", "database": "AGR" }, { "id": "HGNC:29223", "url": "https://alliancegenome.org/gene/HGNC:29223#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041008-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041008-117#orthology", "database": "AGR" }, { "id": "FB:FBgn0039590", "url": "https://alliancegenome.org/gene/FB:FBgn0039590#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1158, "end_pos": 1160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1270, "end_pos": 1272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1409, "end_pos": 1411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 477, "end_pos": 479, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z154", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z154" }, { "id": "PF24883", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24883" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Nephrocystin 3-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 181, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z154", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z154" }, { "id": "PF25520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TANC1/2-like AAA+ ATPase lid", "eco_id": "ECO_0000259", "start_pos": 248, "end_pos": 331, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z154", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z154" }, { "id": "PF25521", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25521" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TANC1/2-like winged helix", "eco_id": "ECO_0000259", "start_pos": 332, "end_pos": 458, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 201, 1430 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1158, "end_pos": 1160 }, { "start_pos": 1270, "end_pos": 1272 }, { "start_pos": 1409, "end_pos": 1411 }, { "start_pos": 477, "end_pos": 479 }, { "start_pos": 556, "end_pos": 558 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"https://www.uniprot.org/uniprotkb/A0A8M6Z157" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M6Z157", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z157/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z157", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z157" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101882447", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z157", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z157", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z157", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01644", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z164-1", "uniprot_ac": "A0A8M6Z164", "uniprot_id": "A0A8M6Z164_DANRE", "mass": { "chemical_mass": 60261.0, "monoisotopic_mass": 60261.0 }, "refseq": { "ac": "XP_017210805", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210805" }, "gene_names": [ { "name": "LOC101884898", "type": "recommended", "evidence": [ { "id": "A0A8M6Z164", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z164" } ] }, { "name": "LOC101884898", "type": "synonym", "evidence": [ { "id": "XP_017210805", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210805" } ] }, { "name": "LOC101886754", "type": "synonym", "evidence": [ { "id": "A0A8M6Z164", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z164" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z164", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z164/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017210805", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210805" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017210805.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017210805", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210805" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z164", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z164" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101884898", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z164", "locus": {} } ], "crossref": [ { "id": "101884898", "url": "https://www.ncbi.nlm.nih.gov/gene/101884898", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "101886754", "url": "https://www.ncbi.nlm.nih.gov/gene/101886754", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:101884898", "url": 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membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1C1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1C1" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1C1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1C1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1C1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1C1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "transmembrane transport", "id": "GO:0055085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055085", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1C1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1C1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z1D5-1", "uniprot_ac": "A0A8M6Z1D5", "uniprot_id": "A0A8M6Z1D5_DANRE", "mass": { "chemical_mass": 170410.0, "monoisotopic_mass": 170410.0 }, "refseq": { "ac": "XP_017213515", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213515" }, "gene_names": [ { "name": "LOC108191474", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1D5" } ] }, { "name": "LOC108191474", "type": "synonym", "evidence": [ { "id": "XP_017213515", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213515" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1D5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1D5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017213515", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213515" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017213515.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213515", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213515" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1D5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1D5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108191474", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1D5", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z1D5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z1D5", "database": "AlphaFoldDB", "categories": [] }, { "id": "108191474", "url": "https://www.ncbi.nlm.nih.gov/gene/108191474", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:108191474", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191474", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1D5", "url": "https://www.orthodb.org/?gene=A0A8M6Z1D5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_017213515", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213515", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1D5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1D5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1D5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDQGWIRFPLLVIVLLFWMNADGYSYSTSPNADQWLGQPSEKTFLPLVVQSSVAEAPVTGVLLEEVVSSLPKNRPKFNLLQVVKDGVSSSSDSTPQTLNTPSSASLPMDQSGKSGSVSFKGSSGSTTAYATSGSGQIVFAQRESGSFSSNAGVSGQSTNDQSSPSLSSSASQGTTYGLTSLVQGTNQFAPGSSSSYATISLPKYVSQLKTGPSSKPFMTVYGTQTLQGSTTYGGKIQTTDTTSQFVKGSTSPDVVISLSQDVSSQSAVPSSKQITSVYSTQTGSSAPFTLQELFQGQDSTSKFVSGSLTPSVAVSLAQGVSSQSALPSSKRITSVYSTQTGSSAPFTLQRLVQAPDMSTVISGSLTPSEAILSAQGVPSYSTVPSSKKTITSDFSTQTGSSAPFTFQESTTYGGLIQAQDPSQSVLGSSTPYVAVSIPQVVTSQSAMPSSKQTTSVYSTQTGSSAPFTLQELLQGQDSISKVDSVSSTPFVSVSLPQVFTSQSATVPSPKKPITSVYSTHRLVQAPGVPHKVVSGSLTPSVAVSLTQGVPSQSTVPSSKKTITSVYSSQKGSSAPFTLQRLVQAPDTTSTVISESLTPSKAILLTQGVPSQSAVPSSKTITSVYSTQTGSSAPFTLQRLVQAPDTSTVISGSLTPSETILLAQGVPRQSAVPSLKKTITSVHSTQTGSSAPFTFQEITANGGLIQAQDTSQSVLGLSTPYVAVSIPQVITSQSAVPSSKQTASVYSTQTGSSAPFTLQELLQGQDSTSKVDSVSSTPFVSVSLPQVFTSQSATVPSSKKPITSVLGTHRLVQAPDVLHKVVSGSLTPSVAVSLAQVVPSQSAVPSSKKTITSVYSTQTGSSAPFALQELFQGQDSTSKVVSGSLTPSVDVSLAQVVPSQSAVPSSKKTITSVYSTQTGSSAPFTLQRLVQAPDTTSTVISGSLTPSETILLAQGVPSQSAVPSSKKTITSVHSTQTGSSAPFTLQELFQGQDSTSKVFSGSLTPSVDVSLAQVVPSQSAVPSSKKTITSVYSTQTGSSAPFTLQRLVQAPDTTSTVISGSLTPSETILLAQGVPSQSAVPSSKKTITSVHSTQTGSSAPITFQESTTYGGTIQAQGTSQSVSGSSTPFVAVSMPQGVTSQSAVPSSKQITSVYSTQIGSSAPFTLQRLVKAQDTSKVISEFSAPSVAVALAQAVPSQSAVPSSKQITSVFKTQQGSSAPFTFQGGTTYGVPIQAQDTTSQFVSRSSTPVVAVSLPQDVVSPSITVPSSKKPITSVYGTLTGSSALFTLQGLLQGKESTSQVVSVSSPYVAVSLPQGITSQSTIVPSSKKTNTSVYGTQTESSTPFVLQGTLKSQDSTSQVVSVSSTPYVSVSLPQDVTSQSAVPSSKQITSVYSTQTGSSAPFTLQRLVQAQDATSEIGSGSSTPSVVVSLDQGVPSSKQITSVYDTQTGSSAPFTLQGGTAYSGLTQALDSASQVVLGSSSPYVAVSLPQVVTIQSTTVPSSKKPFASVYGTQTGSSAPLALQGLLQGQESSQVFSVSSPYVAVSLPQGITSQSTTVPSSKQITTVYGTQTSSSAPLTLQRLFQGQGSTRVSGSSSPYVAVSLPQGVTSQSMTVPISKQITSSVYSTQTGSSPTLNVQGLLHPQDSTDQFTLRHDSVKG", "length": 1660, "header": "tr|A0A8M6Z1D5-1|A0A8M6Z1D5_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108191474 PE=4 SV=2 CANONICAL=A0A8M6Z1D5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1D5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1D5/entry#A0A8M6Z1D5-1", "sequence": { "sequence": "MDQGWIRFPLLVIVLLFWMNADGYSYSTSPNADQWLGQPSEKTFLPLVVQSSVAEAPVTGVLLEEVVSSLPKNRPKFNLLQVVKDGVSSSSDSTPQTLNTPSSASLPMDQSGKSGSVSFKGSSGSTTAYATSGSGQIVFAQRESGSFSSNAGVSGQSTNDQSSPSLSSSASQGTTYGLTSLVQGTNQFAPGSSSSYATISLPKYVSQLKTGPSSKPFMTVYGTQTLQGSTTYGGKIQTTDTTSQFVKGSTSPDVVISLSQDVSSQSAVPSSKQITSVYSTQTGSSAPFTLQELFQGQDSTSKFVSGSLTPSVAVSLAQGVSSQSALPSSKRITSVYSTQTGSSAPFTLQRLVQAPDMSTVISGSLTPSEAILSAQGVPSYSTVPSSKKTITSDFSTQTGSSAPFTFQESTTYGGLIQAQDPSQSVLGSSTPYVAVSIPQVVTSQSAMPSSKQTTSVYSTQTGSSAPFTLQELLQGQDSISKVDSVSSTPFVSVSLPQVFTSQSATVPSPKKPITSVYSTHRLVQAPGVPHKVVSGSLTPSVAVSLTQGVPSQSTVPSSKKTITSVYSSQKGSSAPFTLQRLVQAPDTTSTVISESLTPSKAILLTQGVPSQSAVPSSKTITSVYSTQTGSSAPFTLQRLVQAPDTSTVISGSLTPSETILLAQGVPRQSAVPSLKKTITSVHSTQTGSSAPFTFQEITANGGLIQAQDTSQSVLGLSTPYVAVSIPQVITSQSAVPSSKQTASVYSTQTGSSAPFTLQELLQGQDSTSKVDSVSSTPFVSVSLPQVFTSQSATVPSSKKPITSVLGTHRLVQAPDVLHKVVSGSLTPSVAVSLAQVVPSQSAVPSSKKTITSVYSTQTGSSAPFALQELFQGQDSTSKVVSGSLTPSVDVSLAQVVPSQSAVPSSKKTITSVYSTQTGSSAPFTLQRLVQAPDTTSTVISGSLTPSETILLAQGVPSQSAVPSSKKTITSVHSTQTGSSAPFTLQELFQGQDSTSKVFSGSLTPSVDVSLAQVVPSQSAVPSSKKTITSVYSTQTGSSAPFTLQRLVQAPDTTSTVISGSLTPSETILLAQGVPSQSAVPSSKKTITSVHSTQTGSSAPITFQESTTYGGTIQAQGTSQSVSGSSTPFVAVSMPQGVTSQSAVPSSKQITSVYSTQIGSSAPFTLQRLVKAQDTSKVISEFSAPSVAVALAQAVPSQSAVPSSKQITSVFKTQQGSSAPFTFQGGTTYGVPIQAQDTTSQFVSRSSTPVVAVSLPQDVVSPSITVPSSKKPITSVYGTLTGSSALFTLQGLLQGKESTSQVVSVSSPYVAVSLPQGITSQSTIVPSSKKTNTSVYGTQTESSTPFVLQGTLKSQDSTSQVVSVSSTPYVSVSLPQDVTSQSAVPSSKQITSVYSTQTGSSAPFTLQRLVQAQDATSEIGSGSSTPSVVVSLDQGVPSSKQITSVYDTQTGSSAPFTLQGGTAYSGLTQALDSASQVVLGSSSPYVAVSLPQVVTIQSTTVPSSKKPFASVYGTQTGSSAPLALQGLLQGQESSQVFSVSSPYVAVSLPQGITSQSTTVPSSKQITTVYGTQTSSSAPLTLQRLFQGQGSTRVSGSSSPYVAVSLPQGVTSQSMTVPISKQITSSVYSTQTGSSPTLNVQGLLHPQDSTDQFTLRHDSVKG", "length": 1660, "header": "tr|A0A8M6Z1D5-1|A0A8M6Z1D5_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108191474 PE=4 SV=2 CANONICAL=A0A8M6Z1D5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1424, "start_aa": "Thr", "end_pos": 1424, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1424", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:108191474", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191474", "resource": "KEGG Pathway" } ], "orthologs": [], 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017206561.1. 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The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol." }, "synonyms": [ { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "nonalcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "non-alcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "NAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": 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"description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "NAFLD2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "fatty liver disease, nonalcoholic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "liver disease, alcoholic, susceptibility to, 1", "description": "" }, { "id": "MIM:613282", "resource": "MIM", "url": "https://www.omim.org/entry/613282", "name": "Non-alcoholic fatty liver disease 1", "description": "Non-alcoholic fatty liver disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ] }, { "disease_id": "DOID:0080270", "recommended_name": { "id": "DOID:0080270", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080270", "name": "autosomal dominant nonsyndromic deafness 34", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q44." }, "synonyms": [ { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "hearing loss, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "DFNA34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "autosomal dominant nonsyndromic deafness 34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "deafness, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MIM:617772", "resource": "MIM", "url": "https://www.omim.org/entry/617772", "name": "Deafness, autosomal dominant, 34, with or without inflammation", "description": "Deafness, autosomal dominant, 34, with or without inflammation" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080270" } ] }, { "disease_id": "DOID:0090029", "recommended_name": { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "CINCA Syndrome", "description": "An autoimmune disease characterized by neonatal onset of cutaneous symptoms, chronic meningitis, and joint manifestations with recurrent fever and inflammation that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q." }, "synonyms": [ { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "IOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "NOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic infantile neurological cutaneous articular syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "Chronic Infantile Neurological, Cutaneous, and Articular (CINCA) syndrome is characterized by skin rash, joint involvement, chronic meningitis with granulocytes and, in some cases, sensorineural hearing loss and ocular signs." }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA/NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Neonatal-Onset Multisystem Inflammatory Disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic infantile neurological cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal onset multisystem inflammatory disease", "description": "" }, { "id": "MIM:607115", "resource": "MIM", "url": "https://www.omim.org/entry/607115", "name": "Chronic infantile neurologic cutaneous and articular syndrome", "description": "Chronic infantile neurologic cutaneous and articular syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090029", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090029" } ] }, { "disease_id": "DOID:0090062", "recommended_name": { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "familial cold autoinflammatory syndrome 1", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP gene on chromosome 1q44." }, "synonyms": [ { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "FCAS1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "Any familial cold autoinflammatory syndrome in which the cause of the disease is a mutation in the NLRP3 gene." }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "NLRP3 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP3", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome type 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold inflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "FCAS1", "description": "" }, { "id": "MIM:120100", "resource": "MIM", "url": "https://www.omim.org/entry/120100", "name": "Familial cold autoinflammatory syndrome 1", "description": "Familial cold autoinflammatory syndrome 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090062", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090062" } ] }, { "disease_id": "DOID:0090063", "recommended_name": { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "familial cold autoinflammatory syndrome 2", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP12 gene on chromosome 19q13." }, "synonyms": [ { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "An autoinflammatory disease caused by mutations in the NLRP12 gene. It is characterized by periodic fevers beginning in the first year of life that are triggered by cold exposure. Episodes occur more than once per month." }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NALP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NAPS12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome type 2", "description": "" }, { "id": "MIM:611762", "resource": "MIM", "url": "https://www.omim.org/entry/611762", "name": "Familial cold autoinflammatory syndrome 2", "description": "Familial cold autoinflammatory syndrome 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090063" } ] }, { "disease_id": "DOID:12351", "recommended_name": { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "alcoholic hepatitis", "description": "" }, "synonyms": [ { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic hepatitis", "description": "" }, { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic liver disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12351" } ] }, { "disease_id": "DOID:1555", "recommended_name": { "id": "DOID:1555", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1555", "name": "urticaria", "description": "A skin disease characterized by skin rash notable for pale red, raised and itchy bumps, located_in the upper dermis." }, "synonyms": [], "unlinked_id_list": [ "DOID:0060220" ], "evidence": [ { "id": "1555", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1555" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:9452", "recommended_name": { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes." }, "synonyms": [ { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Fatty change of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Steatosis of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "alcoholic fatty liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic lipidosis", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "SLD", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "fatty liver disease", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "fatal neonatal hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1F5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1F5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-23k10.2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1F5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z1F5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z1F5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "565381", "url": "https://www.ncbi.nlm.nih.gov/gene/565381", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565381", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565381", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETIVIFV", "url": "https://omabrowser.org/oma/group/ETIVIFV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z1F5", "url": "https://www.orthodb.org/?gene=A0A8M6Z1F5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017206561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206561", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1F5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1F5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1F5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131122-52", "url": "https://zfin.org/ZDB-GENE-131122-52", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "METEGPDSPEPSCVSLRSDHSKAHHVLFKDEDPFEYSSGQTGRSSPTPSHVSLASNMSINQPLEFKSCSNTLLLKEIQEAIQSVLRIRFQCLHEGLSKHSVLIPLNDIYTELYITEGEGGELNNEHEIRWIETACRRALTEDRPVNLNDIFKPLHGQDRPIRTVLTKGVAGIGKTVSVQKFIIDWAEGEANQDIWFIFPLPFRELNLLKDQSFSLKGLLQYFMNIELDISLHEGKIMFIFDGLDECRLPLDFHNNVKLCDVTESASVDVLLTNIIRGNLLPSSLIWITSRPAAADVVPSKCIHRVTEVRGFSDPQKEEYIRKKVSDQTLSDRIISHLKSSRSLYIMCHIPVFCWISATVLKKMLSEAESAEIPNTLTQMYTQFLMLQLRIKNEKAYDKKSSDIDIVLKLGELAFQQLEKLNLIFYKEDLREYGIDEQEASVYSGLFREESGMFQGKVYSFVHLSVQEHLAALYVYLYFVNENINKLNQPNFLTSILKCVPTVFDVYQTAVKKALQSTSGHLDLFLRFLLGFSLESNQNLLGDLQVQTESSSDSREQIVGFIKEKIKESPPPEKMINLFHCLNELNDHSLVEEIQDFLQSESRINMKLTASQWSAMVFVLLTSGQKLDVFDLNKYIGTYILPDESLQRLQPVLAASRTAKLCEHNLTKRGYSVLVSVLTSKTSCLRELNLTRSAVNDSGLKLLCSGLENPQCKLETLRLEFCGVSDKGCDFLASALRSNPSHLKALDLSGNTLNFTGLKNLLAEFQKPHCKLQRLCLRLCGLTDVGCDALASVLRSDPSHLTELNLSGNKLGDLGMKLLAGGLQNPHCKLQILRLGDCSITHEGCAALASALRSNPSHLRELDLSGNKLNNAGVQILSGELENPDCNLEILRLENCDVGEEGCAALAEALKSNPLTLKELDLCWNKLGNSGVQRLCTSLENPNCTLGVLRLTGCNISENGCAALASVLRSNPSYLRDLDLSHNDLRSSGVRLLSSALEKPDCKLEILRLEYCKITDDGCAVLASALKSNPSHLRELYLYMNSFNLTASGRQLLSKIKDDPHYKLQTLHYESHFFC", "length": 1074, "header": "tr|A0A8M6Z1F5-1|A0A8M6Z1F5_DANRE Isoform 1 of Protein NLRC3 OS=Danio rerio OX=7955 GN=si:dkey-23k10.2 PE=4 SV=1 CANONICAL=A0A8M6Z1F5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1F5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1F5/entry#A0A8M6Z1F5-1", "sequence": { "sequence": "METEGPDSPEPSCVSLRSDHSKAHHVLFKDEDPFEYSSGQTGRSSPTPSHVSLASNMSINQPLEFKSCSNTLLLKEIQEAIQSVLRIRFQCLHEGLSKHSVLIPLNDIYTELYITEGEGGELNNEHEIRWIETACRRALTEDRPVNLNDIFKPLHGQDRPIRTVLTKGVAGIGKTVSVQKFIIDWAEGEANQDIWFIFPLPFRELNLLKDQSFSLKGLLQYFMNIELDISLHEGKIMFIFDGLDECRLPLDFHNNVKLCDVTESASVDVLLTNIIRGNLLPSSLIWITSRPAAADVVPSKCIHRVTEVRGFSDPQKEEYIRKKVSDQTLSDRIISHLKSSRSLYIMCHIPVFCWISATVLKKMLSEAESAEIPNTLTQMYTQFLMLQLRIKNEKAYDKKSSDIDIVLKLGELAFQQLEKLNLIFYKEDLREYGIDEQEASVYSGLFREESGMFQGKVYSFVHLSVQEHLAALYVYLYFVNENINKLNQPNFLTSILKCVPTVFDVYQTAVKKALQSTSGHLDLFLRFLLGFSLESNQNLLGDLQVQTESSSDSREQIVGFIKEKIKESPPPEKMINLFHCLNELNDHSLVEEIQDFLQSESRINMKLTASQWSAMVFVLLTSGQKLDVFDLNKYIGTYILPDESLQRLQPVLAASRTAKLCEHNLTKRGYSVLVSVLTSKTSCLRELNLTRSAVNDSGLKLLCSGLENPQCKLETLRLEFCGVSDKGCDFLASALRSNPSHLKALDLSGNTLNFTGLKNLLAEFQKPHCKLQRLCLRLCGLTDVGCDALASVLRSDPSHLTELNLSGNKLGDLGMKLLAGGLQNPHCKLQILRLGDCSITHEGCAALASALRSNPSHLRELDLSGNKLNNAGVQILSGELENPDCNLEILRLENCDVGEEGCAALAEALKSNPLTLKELDLCWNKLGNSGVQRLCTSLENPNCTLGVLRLTGCNISENGCAALASVLRSNPSYLRDLDLSHNDLRSSGVRLLSSALEKPDCKLEILRLEYCKITDDGCAVLASALKSNPSHLRELYLYMNSFNLTASGRQLLSKIKDDPHYKLQTLHYESHFFC", "length": 1074, "header": "tr|A0A8M6Z1F5-1|A0A8M6Z1F5_DANRE Isoform 1 of Protein NLRC3 OS=Danio rerio OX=7955 GN=si:dkey-23k10.2 PE=4 SV=1 CANONICAL=A0A8M6Z1F5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 47, "start_aa": "Thr", "end_pos": 47, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr47", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:565381", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565381", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JW23-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPATAKDALHRLSTYLEELEAGELKKFKLYLGIAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGEDLVRVTPSNGLCSLESQSTCLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGPWCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTSRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFTAMYCALHGREAVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAEDGPPEPPGAQTQSTHSQERNILPDIYSAYLSATICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIANRNLIRLDLSGNSIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSNNSHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVNTCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGISQTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFGMDLNKVTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1PS14-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:dkey-222h21.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNMLQRIKNQHKTSLKNKYERLFEGIEVKETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPENLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGIDVSDASVYSGICTEILKEESVIQQRKVYSFIHLSFQEFLAAFHVFYHHITCSTEASLDSLHDLQKRIINKSTESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKRSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELKLQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITPGLRKYACVLTLDPNTAHTHLVLSEKNRQARNVTDPQPYPDHPDRFKNNEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYSCDTIYTVWHNNKSADIIAPSACTNRVGVYVDVPSGSLSFYSVTDTHTLTLIHTFNTTFTEELYTGFGIYPEASVSLCQI", "length": 892 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RJ47-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "si:ch211-201o1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSAEKSDDAPATGSSPEDLQAEQHEQKKSDSSTVSHVSMKSGRSITPPLDFRKDEQGNTERAKQERAESSTASHLSMKSDRSITPPLDFISGEQKQTERKSVDDHAVSTSADRVCQRHHRALDVFCQTDNIHICCICVEEEHQGHRKTYTAKLNVPDSQSMLLHIMEKMRSEDFNTFKRELSEDYAGCLGAQSEELSVSEAAENIMRSFGGEAALRLILHFQTKANPLKKITDANKTKLKNKCQNINEGNSSYGKQSLLMEVYTDLYFTEGGSGEINNEHEVLRNEMISQSRTTQEVLYACDEIFKTLPGQRTQVRTVLTMGIAGIGKHVSVQKFILDWAEGKANQDIEIIIHLPFRDLSCREESCSLLQLVHQYSPELREADLQHLKVLFILDGLELCQYPLHFHKNVYCADINEKVPVDALLTNLIKGNLLPSALLWITTRPSTAGRIPPECVHRVTEIRGFSDDQKDSYFRKKISDQTLADEIIRHIKSCQSLYIMCHMPIFCWISATVLENIMREGQSEELPRTLTGMFTHFLLLQVSLKHKKFNGADGDNPKKLSEFDQTFILKLGELAFQQMEKGDLIFREEDLREGGIDVSKVSEYSVCTEFFREELGLYREKLYGFLHVSYQEFLAAIYAHFTCVNDGRNVFLKDESRSSVDLCDVHQTAVEKALQSENGHLDLFLRFLLGLSVDSNFNLLQDLLKDTSCKPRVDTSSTVSFIKEKVKLEQSPERIINLFHCLNQLNDNSLVEEIKAAMKSGTLLGSELDPEQWSALAYVYLTSGEEIEEFDMIKSNQLRLLPVLRICKKARLNCCNLSFASCGLVASALKSVNSPLTELDLSNCKLNIFGMNTLLDGLKSPHSKVKKLRLAGCFFPSETCANLALALKSVNSQVTELDLSYNKITDGVHKFCAGLTSQNCKLQKLVLKRCGLTKASCAHLASVLKSNTHLMELELKGNDLQDSGVELLSTGLMDPQCRLEKLGLSGCMITKVGCNSLASALTSNADCMSELDLTYNHPGDSGVKLLTAKKEDPNCKLEKLHVKKRGECRMKPGLRKYACQLTVDPNTIHPRLIVSNDNRTISETTEHQKYPVHPDRYTLYPQAMCREPLADRSYFEVKCTGGVSIGVAYKTSDRTEDLMGFNNTFPSLMCLNGRIKLWQNNDVIHYELPVFAQSSRVGVYVDQYQGSLSYYSICKDTLIHLHTHHTEFTSPLYIGFLFMPDSSVTLLDDSL", "length": 1231 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AHM3-1", "protein_name": "Uncharacterized protein si:dkey-23k10.3 isoform X1", "gene_name": "si:dkey-23k10.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVFLHTTHLYSGQTEVSGYKSTVLRSFVRPSYILKFERNCYHEFSRIHLLSTLLQWQVNLETLRFSACGITDEACFALAKALTSKLSHLRELDLSENKLGDAGVMVLSAALENNCSDLVSLKMNDCDLTYEGCSHLASALASNPSHLRELDLSKNKLDDVEMLVLAAGLENSSCKLEKLRLVKCGLTDEGFVVLNKALRSNPSHLKELDLSENSLCYLHTMLLSSVLESPYWELKTLKLVNCSFTEEGGAALMSALRSNPSHLRELDLSKNNIGYLTMMVLSSAMEIPYWELEILRLNDCGITDDGFAALGAGLRSNPSYLRELDLSKNKLGEFGVHMLSIALEMPYCQLETLRLVSCDITGNGWIVLVSALRSNPSHLRNLDLSGNNLECFEIKLLSEVLESPYCKLETLKLRNCNLKDEECVSLASALRLKISKLRELDLSENKLGDSGVKAFFAELEGHLSKFDALRFVNCGLTDEGCGVLASVLSSNPSHLKELDLSGNKVEDSGVKMLSDGLEDYCCRLETLKLVGCGLTDEGCASLASALTSNSSHLRVLDLSKNKLSDSGVRLISTGLENPHCKVEILWLVDCDVNDEGCAALASALTFNFSNLRELDLSENNLGDFGVKLLSAGLEDPHCKLEILKLKNCGFTDGGIAALAPVLGSDHSYLKNVDLSGNKFEDFGVQLLSIAFY", "length": 692 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3ANC0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch73-168d20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSRKRRSSSPESSCVSIKSDASMDNPPTLRLGESPAKHRRSSSLGSSCVSMKSDASMDNPPTLRLGESPAKHRRSSSPESSCVSMKSDASMDNPPTLRLGESPAKHSDNQKRSQSNKGQKQLDAIFKDLEETNIDEMRKVLRRFKMLLSPDYSVRDEEEEEGQRQINEAFLKITLHALQKMNQTDLASKLQTKLISVSQQQLKSRLKQRFERFTEGVSNRGNTKLLNDIYTEVYITEGGAGNIDDEHEVRQIETSSSRFPEIPIRCCDIFKSLLGQDKAIRTVLTKGVAGIGKTASVQKFILDWAEGKANQDVHFIFPLPFRDLNLIKEKRMSLMELLCCFCPELKPIDYNNFKTVFIYDGLDEWRLPLDFRNNEILWDMNKVASVDALLTNLLQGNLLPSAVHWITTRPAAACQIPAEFIDRVTEVRGFKDLQRAEYFWKRIKDQNLANKIITHIQSSRSLHIMCRIPVFCWISATVLEKIFGEANSADIPKTLTQMFIHLLIVQTNLKTQKYDRECDVNLEKARKSILSLAKLAFEQLEKGNLIFYEEDLKQCGIDVREASVCSGVCTQIFREEFGLQLQKVFSFVHLSVQEFLAALFKFLSFAEENNKSSMTQFMKNEVDRALQSPNGHLDLFLRFLLGLSLDSNQTLLQGLFTPLDTSHSRDETIEYIKSKIRENPSPERSINLFYCLNELNDHSLVQEVQTYLTSTRSHRLSGVKLSPALWSALVFVLLNSTKDLDEFELRQYDFTEECLLRLLPVVKASRKADLKGGNLTDQICSALASALSSSSCCLRELDLSENRLQLSGIRLFSAGLKSPNCKLEILKLSNCSIREEGCASLVSALLSNPSHLRELNLNSNQPGYSTVKLLSDLLENPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLNGSNIREKDCAAFISSLLSNPFHLRELSLSWNKPGDSGVKLLSDLLKDSRCKLEKLELECCSIIEEGCAALALALVSNPSHLRELNLNNNEPGDLGVNLLSFLLKNPQCKLEKLELEYCCIGAKSCASLASAFVSNPSHLRELNLNWNTPEYPAVKLLSDYLKDPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLEYCCIGEEGCAALVSGLKSNPSHLRELNLNRNEPGNLGAKMLSDLLKDPLFELEKLELDDCSIENNGFADLVSGLKSNPSNIRELNLNSNKFIFSGLNLLCDLLRDQQCKLRKLQLECCNIDEEGCAALALALISNPSHLRELNLNYNNPGGLGVKLLSVLLKNPHCKLEKLELSHCSISENYLAALNSALSSNPAHLRELNLNYNENTRQ", "length": 1388 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQ59-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKIFQNLTAESGKGIRDYVVQIRFCFIMDDTQISRDENVSPGCSSVHQKRSDPEPSCVSMRSDWSMDPPISFKSKDTPPDFSSVHQKSTESEPSCVSMRSDDESVDQPLHVRSGDTETDLSHEALNTFRSDLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIIPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLMNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHLLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDGFEEIKKPSLWSKVKDLLYLNSSQLVSLSELHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQIILQRLMILKSRSIQINKTVEYIKMKIRTIDSPEKFINLFHCLNELGDHSLVEEIQQYLKSGRINRAKLSESQWSAVAFVLLTSEKKLEEFHINEFVGETEKIFIFMKLLPVIRECRSVQLNNCGLTDEGCAALASALRSNPEHLRELNLSGNRLGDSVTLLSALLEDPRCNLEILWLSYCGLTDEGCAALASALRLNPEHLRELNLSHNNISKSTVKLLSDLKHNPHNKLETLYI", "length": 837 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B0M3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "si:dkey-7i4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESDEQHNDTLVQMGSSGNSGINADLRAEKEATVIAPLLNGNNITGPVTFNYCSNSAENEPQKYPKTADKHTEKQDDLKLQKILETHRTYMKKKVDCILDCTKENAEHFKAFYTELFIAEGDMQDVNQEHEILKIDDAFKKKKASLRSIRCKDIFAELKAKSEKNTVLTKGIAGIGKTVSVRKFILDWAEGQTNHDIHCVFLLPFREINLMTNEDFNLHEFLLKFYPELKELETSVLFQQCNLAFIFDGLDESRLPLNFKSRTLNNVEERSSVDMLFTSLVKGNLLPSALVWVTSRPAAANQIPPRYVGLFTEVQGFTDQQKEKYFRNRIADETQASKIISHIKTSRSLYIMCHIPVFCWITATVLQDILQRNIESIGTTLTEMYIHFLLIQMNMKSQKYDPEEEREYAKLLEANREVILKLAKLAFEQLKKENVVFYEQDLKDCGIDVNVEFTGMIAEIFKVEHGLHEAKVFYFVHLSVQEFLAAVYVFFCFLNRNTHELTFFFESSQNTPRELQFLFKKTFRKVKFHDLIKRATDKAMRSKRGHLDLFLRFLLGISLESSQNLLKGLFSHVIDTTRSIKKISPHFKHLQNKNISCDCSVNLFFCLLELKDHSLYEEIQRSLNSDRRPSKELSSSMCTVLTYIVLMSEKELDELNPKRFTSSQENYRKLVPAVRCCRKALFNGCGLDEMSFQTISSALQSSDSYLTELELSNNHLQDSGVKLLSDGLKSSHCQLNILRLCGCGLTDQSCESLSSALQSSNSVLRELDMSNNMLKDSGVKLLAVALKSLNCKLERLRFSMCNLTAESCESLSSVVELSNSVLRELDLSNNDLQDSGVKLLSDGLKRNCRLEILRLSGCMVTEVGCGFLSSALSSTTSTLRELDLSYNHPGDSGEKLLSDAHNQPNCRLCVDHGGEFRLTTGLHKYARFFTLDPNTANARLILSEENRKVTCVRKKQPYPDHPDRFEGYLQVLCRESVCGRSYWEIEWTGVVFISVSYSSIGRMGSDKECWFGFSNQSWSLFCSSDRCSFTHSSTEIDLPVKHTSSRIGVYVDHSAGTLSFYSVSDTVSLIHSVQTTFTQPLHPGFYISLGSSVKLC", "length": 1096 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YSM0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch211-181d7.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSHKQTLKYFSPVCSSVQQERSDSAEPSSVSVKSHWSIDPPPQMTERRDSLSLALQERSDSPEPSHVSMKSDWSIDPPPQMKEENRSLVQQERSPKSSCVSMKRDWSIDPPPQMNDEDGQKRLSLVQQERSDSAEPSLVSMKSDWSIDPPPQMKDGDRQKSLSLVQQERSDSPEPSHVTMKSNWSIDPPPQMTDRRDSLRQIPRPRPGAEEPISKKMKYDESVIKSQECMENPSLIFSHEVNTFRVNLLKKFQCLYEGMVTQDNPALLNEIYTELYITESESGEISNEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPETKEIDIFSDKYKILFIFDGLDECRLLLNFKSNEILQHVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLMAQINTKDMKYTGKKDKDMIFKLGKLAYEQLERGNVIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFIHLSVQEHLAALYVHLLFTNHNRNVFEQMTKKTSKTLDILDCFHSNSPENVLLSELHQKAVDEALQSKNGHLDLFLRFLLGLSLESNQILLQELMIKFRSSSDSSEKTVEYIKKRINNICLPEKSINLFYCLNELGDHSLVKEIQQYMDYGTLAETKISCGQWSALVFILLTVEQAMDVFELNKFIGLKKSSDEVLRKLLPVIKKSRSAIMDDCNITAEGCAYLASALGSNPSYLRELDLSANKLQDSGIKKLSKGLQDSHCKLEKLNLYHCGVTNEGCAALASALKSNPEHLRDLNLSENKIGNLGLTCLSEILKNSLCKLEILRLCQCGITDCTDLASALISNPEHLRELELSLNKIGDSGVTALCAAFEDPRFKLEKLGLSGCGLTDEGCAALTSALRSNHEHLRDLDLSGNKVDKEVKGSILQRILEKLNNIQILSV", "length": 1068 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YU37-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch73-24k9.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDNQTFSDAPVCSNESNPEFEPSCVSMKSDQSMDPPMKFKEGHTSADLSDRLNPPGSSCVSMKSDWSMDRPIQFKEEHSSADLSNKSNPGEPSCVSSKSDQSMGPPINVMEEHSAADLRLDPHLKQNGLRSNLLRKFQCLYEGTAMQGDPTLLNEIYTELYITESDSGEINNKHELRQIETRSRRSATEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEEKENQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEQFKVLFIFDGLDECRVSLDFKCDVKLHDVSESASVDVLLTNLIMGNLLPSALIWITSRPAAADLIPSEFVHRVTEIRGFNDPQKEEYFRKRIRDQFLADIIIINLKSSRSLHIMCHIPVFCWISATVLEKIFSQAQSGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEVRDEDMILKLGKLAFEQLVKGNLIFYEEDLRECGLDVTEASVYSGLCTQIFREEFGFYQGKVFCFVHLSIQEHLAALYAHHSLTNKNRNVFKQTKPSLLSKVLNQKKHDSLSVLHQRAVKEASQSKNGHLDLFLRFLLGLSLESSGTLLRELLTQTGSCSYNKEETVQYIKQKIRENRSPERSINLFHCLNELGEDSLMQEIQDYLSSGEIKETKLSSSQWSALVYVLLTSEKKMDFFDLSKFIGPQLRADVVLQKLLPVVKESRSVRLGDCKVTDKVCAALASALRLNSSHLTQLDLIGNKLGDSGVKLLSDGLKDPHCKLKNLMMRDCGVTDEGCAALASALRSNSTHLTELNLNENNLGDAGVKRLSDGLKGPHCKLEILRLWRCGVRDEGCAALASALSSNSTHLKELELSDNKLGDSGVKLLSDALKDPHCKLEKLRLNGCGVREQGCVSLALALRFNPSSHLTELDLTSNELGKSGVKLLSDLRDDPRYKLRHLACDMFGRIIVSSGGGRLDELLPTTSTET", "length": 978 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkey-165e24.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHRVRSGSCVSSSVSLKSDCSKEDPPKFSEKTPSSAQSVRSGLCVSSFVSLKSDCSKEDPPKFSEKTPSSAQSDEDELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNELEKFKQILQEENRQEFVKDYNENRSRITEAALDLTLFFLREMKQDHAADTLQDELLFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAVSRRHQSLETQVEFKHLFKAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQLFPETKGLNLTRSTQFKVLFILDGLDECRLPPNFAGNEMCCDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILNLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSQGKLAFQQLERNNVIFYESDLNDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEGIIAYIKQKLEGNLSPERSINLFYCLSELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELWKFQRSDECLIRLSAIIKNSKRALLQSCNLTVQSCKSLSSILQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLATCNLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSEHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDTLNLDHVGDMRITAGPRKYVCFLTLDPNTANTQLKLSKENRKVKHVREDLRIMRKDRRYPYHPDRFDPVFQVLCRESVCGRCYWEIDWSGDHGVFISVSYKSIRRKRGDACEFGCNAQSWSLLCLSSRFTFRHNNTHTHVPVKPLSRRIGVFVDHSAGTLIFYNIYKDTMSLIHSVQTTFTEPLCPGFGFYSGSSVKLS", "length": 1137 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z5L8-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch211-207e19.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKDFNENRSRITDAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTDHEIRQIEAASRRHQSLEIQVECKHLFEAAEQHEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETEGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVDKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKKQGWFFIQISKNKGMIDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKGEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSADLSPAQWSALVFVLLTSEEELEVFELQKFQRSDECLIRLSAVIKTSKRALLQGCYLTVRSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLQFCNLTVQCCESLSSALQSSNCVLRELDLSINDLQDSGVKKLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKYVCFLTLDPNTAHTELILSEENREVKSVRENQPYPDHPDRFDYYHQVLCRESVCGRCYWEIDWSGDGVVCISVSYKSIRRKGGGDECVFGYNAQSWSLRCDSSRFKFWHNNTHTDLPVEALSSRIGVFVDHSAGILIFYNIYRDTMSLIHSVQTTFTEPLCAGFRVYYPGSSVKLS", "length": 995 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PCI8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTQTTIEKDYSPRFSLVHQKRSEPSCVSIRRDQSVAHPIDFKSEDTQTHLSSVHQERLDPEPSCVSIRSDRSVAHPIDFKSKNTHLSSVHQERSEPEPSCVSIRSDRSVAHPIDFKSEDTQTHLSTFHQKRKEADPSCVSMRSDTFMNQPINIKIGETQNDLKQNLLNTFRSNLLKKFECLYEGTAVQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQNKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSEKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCLNNNRNEFEQISKQSLWSKVRDHFHFNSSKLVSISKLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQGLMKLKIRSIQNNETVEYIKKKIRKINFPEKFINLFHCLNELGDHSLVEEIQQFLKSGGMNEAKLSSSQWSAVVFVLLTSEKKLEKFDINEFAARNNNTEQLFIFKKLQPVIRQCRSVQLSYCGLTDEGCAALASALRSNPEHLRDLYLSGNKLGDSVSLLSGVLEDPHCKLETLWLSDCGLTSKDSAALASALRSNPEHLRVLDLSWNRLGDSVTLLSAVLEDPHCKLETLLLRDCGLTDEGCAALASALRSNPEHLKHLDLSWSNLGDSVTLLSAVLEDPRCKLEKLGLSNCGLAEEGCAALASALRSNPEHLRGLNLSVNNLGDSVTLLSAVLEDPRCKLEKIKLSYCGLTDEGCAALASALRSNPEHLRDLDLSTNNLGDSVTLLSAILEDPHCKLEKLELKNCGLTDEGCAVLASALRSNPEHLRDLNLSWNNLSNSTKKLLSDLKDDPHNKLETLHTSLSV", "length": 1115 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PLT8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "nlrc8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSMNHPKHFKSGETQNDLGSAHQKRSDPEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQKRSDPEPSCVSMKSDWSMDPPMQFKSKDTPPDLSSVHQERSEPEPSCMSMNSDLPLDPPIRYKSGETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQSLWSKTKFMFKTVALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLKLKRRSIKNNKTVEYIKKKIRTIDSPEKSINLFHCLNELGDHSLVEEIQQYLKSGGINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAENNKTEKLVIFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTLLSAVLEDPHCKLEKLWLSYCGVTDEGCAALVSALRSNPEHLRELNLSGNNLGDSVTLLSAVLEDPHCKLEKLRLYYCGLTDEGCAALASALRSNPEHLRDLDLSWNKLGDSVTLLSAVLEDPRCKLEKLELYNCGLTDEGCAALASALRSNPEHLRDLNLSGNKLGDSVTLLSAVLEDPRCKLEKLWLSDCGLTDEGCAALASALRSNPEHLTELDLSWNNLSKSTVRLFSDLKDNPHNKLKTLHI", "length": 1017 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPT2-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSKRKREDEDAASEISSASPGSSCVSVKSDQSMKKNLPDFSDASVTSDLSISKTINQRSASPEFSVLSMTSNRSIGQPENFSDEPVTFDSVLSDALDKPDYEKLHRIKDQHKTSMKNKYERLFEGLKLDETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHRASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFHVFYYHVNTTMDGLRNFASVENLIKGAVDKAIESENGHLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLFREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCGIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTRQKLNWDHGGHFRITPGLRKYACFLTLDPNTAHNQLILSEDKRKVTHVKDPQQYTDYPEKFVHQEQVLCKETLTGRCYWEVEWSGEGTDIAVAYKGIRRKAGSDCWFGYSEKSWSLFYTGNGFNVWHNNKSQIIPAPSPLSNRVGVYLDTESGSLSFYSVSDTHTLTHLHTFNTTFTEPLYAGFRVFDSSLSLCNI", "length": 993 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PSD3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEEQGKMSLSEKHSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKPMSAKSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKQTSAKSVISDSCVSGSVFVKSDCSKDGDLPNFSEETPSSGKSFEHKTSDSDFQTHRKHKGFQDGLLGIFQDLENQIMNYLKHELEKFKKILQKENIIDFVKDFNENRCSIKEAALDLTLYFLREMKQEESADTLEDELIFIHQLKCGLQKKYQCVFEGIAQQGDSRLLKNIYTDLYITQGGSEQVNTEHEVRQIEVASRRHEAQELQVECRHLFEASEQDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQEISFIFPLPFREMNLKEKETLSLMELITQFFPETKGLNLTRRNRFKVLFILDGLDECRLPLNFAGNETCCDVSSPASLDVLLTNLIKGNLLPSALIWITSRPAAASKIPPDCIDRLTEIRGFNDAQKEEYFRKRLTDENQAKEIIDHVKQSKSLFIMCHIPVFCWISATVLQNILQEKRNNDVKHNQADDASKTLQESNTEDTPKTLTQMYTHFLRFQIQQSRRKYNGEYTPDVSWDKDAILSLGKLAFHHLLNNNLIFYDTDLEACGIDVYKASVYSGMCTQIFKEETGIILGTMYCFVHLTLQEFIAALYAHLILDTNKKSVFDQDSKKINESMIDLLKTAVDKALESDNGHLDLFLRFLLGLSLQSNRRILRGLLTPQDQDDQSTEKILQYIKQKFDANLSPERSINLFYCLNELNEQTLVKEIQTHLSKGSLSSADFSSAHWSALAFVLLTSDEEMEEFELQKFHKSDECLIRLSAVIKTCKRALLNDCNLTDRSCSALATVLESDTSLKELNMSNNNLQDSGVKLLCTGLKDMKCELEILRLSDCNITEEGYKALASALRSNPSHLLELDLRGNDPGESGVKELDDLLQDPNCTLKTLRFLSPSAEESCQFVNGVVGKNPLLLKTLNLNDFRSTRNHPFIYEIEDTQVNHLAALLQDKHCRVNMLILGGCSFTDDQWESLTSALKLNPSHLRELILMWNGPGESGVKILSDFLIEPQLKLEKLCLCYCSITEERCEILTSALKSNPSHLRELNLSQNIPGDSGMKNLSDLLMNPQSKLEKLQLCKCSITEEQCVILTSALKSNPSHLRDLNLSLNNLGDSGVKTLSDLLMKPHLKMEKLWLCKCSITEEQCVILASALKSNPSHLRELSLSENNLGDSGVKNLSDLLMKPQFKLEKLHLSHCSITEEQCEILTSALKSNPSHLRELDISKNQIRNTGVNLLCDVLNNSDCKLETLRLNDCGITDVSSLTQCLTNTKALQFLKVLYLRENHIGDSKQELSDVVRDSNCELSVDEFSLPDFGQIKDIKCCIS", "length": 1370 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCS9-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLQKKNEDEDEESASEMSYPPPESSCVSMKSDWSMVYPPDLSDASVTSDPNNSKRKGQHLEFKESSCVSVMSNRSITPPEMKKIGLKSEDNMLEKIKNKHKTSMKHKYERLFEGVKLHENQTLLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVGVSDASVYSGICTEIFKEESVIQQRKVYSFTHLSIQEFLAAFYVFYYHITCSTEACFDSLHDLQRRAVDKAIESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITSGLRKYACFLTLDPITAHTQLQLSEENRKASIVTDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGLVAVAYKGIGRKSGFDCCFGHNEHSWCLYCSDEVYSVWDNNKSVDVFGPSSRTNRVGVYVDVPSGCLSFYSVSDTNTLTHIHTFNTTFTEELYAGFKVYPGSSVSLCPVKPAEVPP", "length": 988 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUW9-1", "protein_name": "NLR family CARD domain-containing protein 3 isoform X1", "gene_name": "si:ch211-196h16.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKGNTGFRVKPPEPSGVSMKSDRSMHHPLKFKGGIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDPMFRPPEPSVSEKSGQSVDPTLKFSVHTCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDIGEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSINLFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQLDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLRLRCCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLCRCGVSDEGCAALVSVLSSNSSNLRELNLTENKVGDSGVKLLSAGLKENSKLEKLWLFICGVSDEGCAALASILRSNSSNLRELDLTGNKVGDSGVKLLSAGLKDPHCKLEKLTLDFCGVSDEGCAALASALRSNSSNLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC", "length": 1041 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32T552-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:ch73-50f9.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSGKHSVRSGSCVSRSVSLKSDESRKGLPPEFSEQPPSSNRSVEYELSDSVDKTHCNRKSFTDHLLRIFQDLESKIFKVLKNELERFRQILQGENTQDFVKGSNENQSSITKSALDLTLLFLREMKQDEVADTLENELLFINRLKSSLKKTYQSVSEGIAQQGDSTLLNNIYTDLYITQGANEQVNTEHEIRQIEAASRCHKSLEIQVECKHLFEAPEQDKQIRTVLTKGVAGIGKSVSVQKFVVDWAEGKANQDISLIFPLPFREMNLKEKEKQSLKDLITQLFPEVKGLNLTRRTRNKVLFILDGLDECRLPLNFAGNETCHDVSAPAYLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLADQNLAMEIIEHIKQSKSLHIMCHIPVFCWISATVLQNVLKETKVKHKACAKTLQESPKTLTQMYTHFLRFQMQQSRQKYDGKNTDGVSWDQNFILSLGKLAYQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKQETGIILGNLYCFLHLSIQEFIAALYGHLYLDIKKKSVFTGQKHKNKGMTHLLKTAVDKALESDNGHLDLYLRFLLGLSLQTNRQLLRGLLTQQDKSDQSKEEIVVYIKQKLEENLSPERAINLLYCLNELNDHSLMKEIQSHLRDGSLSSADLSPAQWSALTFVLLTSEEELDEFDLQKFKKSDECLIRLSAVIKSSKRALLQCCNLTAQSCESLSSALQSSNCVLRELELSNNDLQDSGVKLLSCGLRSLNCPLEILRLQCCNLTAQSCESLSLALQSSTCVLRELDLSNNDLQDSGVKLISNGLKSCKLEILRLSGCMVTETGCGFLSSALSSNPTHLRELDLSYNHPGVSGVKLLCQKLEDPNYTLAKLNVDHAGAKRITAGPRKWISHLTLDPNTANTELSLSAENREATRVIEKQPYPDHPDRFDYHPQVLCRESVCGPCYWEIDWSGDVGACISVSYKSVSSKGNDEFGCNDQSWSLSCYSSRFSYGHNNRWTDLPVKPISRRIGVYVDHRAETLRFYNICGNTVHLVHSVRTTFTQPLYAGFKIYPGSSVKLC", "length": 1099 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TA29-1", "protein_name": "NLR family CARD domain containing 9 isoform X3", "gene_name": "nlrc9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTKISKDEDYSPRFSSVHQERSDLEPSCVSMRSEQSMGSPMHFRSEDTEADLSSVYQKRSDPEPSCVSMRSDWSMDLPYNFRSEDTPTDLSSFHHKRTEAEFSRVSMRSDMFINHPINIKNVEAQCNIRQNLLNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFESAVRLCDISESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPMFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDEFEQIKKQSLWFKVKDLFQLNSLECVSLFSLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQRLMKLKSRSMQTNKTVKYIKMKIWTIDSPEKSINLFHCLNELGDHSLVKEIQQYLKSGRINRAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAGNNENKKQKVFQKLLPVIKQSRSVLLYNCGLTEMDWDNLTSALRSNPSDLRVLNLSRNILGNSVTLLSAVLEDPCSKLEKLWLSDCGLTDEGCAALATALRSNPEHLRELNLSWNNLRDSVTLLSAVLEDPRCKLETLWLSKCGITGKSCAVLASALRSNPEHLRDLDLSGNKLGDSVTLLSAVLEDPHCKLKILWLSDCGLTDEGCAALASALRSNPGQLRVLDLSENKLKNSGVMQLCAVLEDPHCKLDKLGLYDCSLTDEGCVALASALRSNPEHLRELDLSVNKLRDSGIKLLSAVLEDPRCKLEKLWLSNCGLTDEACAALASALRSNPEHLRELNLSKNKLGESDVKLLSDLKDDTHYKLKELNY", "length": 1079 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TJY6-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkeyp-100h4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQQIQETRLKGDTRASQTISSPSSSCSMAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKDCPPVFSGETPSSAQSVEFESADSGDETHRRHKSFTDNLQSIFQNLESKMFTFLKNELEKFKKILQENRQEIVKEFNENRSRITEAALDLTIFFLREMKQDQAADTLVGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVKCKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDDQKQEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGFVLHTMYCFLHLSIQEFIAALYQHLILDNDKTQAEKSRDESMIDLLKAAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEANLSPERSINLFYCLNELNDQSLLKQIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAIIKTSKRALLQGCYLTVPSCESLSSVLQSSNCVLRGLDLSNNDLQDSGVNLLSDGLKSQHCKLETLRLVMCNLTVESCESLSSVLQSSNFVLRELDLSNNDLQDSGVKLLSDGLKTVNCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVELLFEKLADPNYTLDKLNLDHGGHTRITAGPRKNACFLTLDPNTTYAFLILSEENREVKTVREYQLYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDDYVDISVSYKSIMRKGVDPECVFGRNAQSWSLCCDSSSFTFWHNDTDTRLPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLWPGFTVWCQSSVKLC", "length": 1125 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TMV3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like", "gene_name": "si:ch211-197e7.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDWSKEDPPKFSEKTPSSAQSVRSGSCVSSSVSLKSDRSKEHPLPNFREKTPSSAQSVEHELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNEMEKFKKILQEENRQEFVKDYNENRSRITEAALDLTLFFLREIKQDQAADTLQDELFSINQFQCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNNEHEIRQLEAASRRHQSLETQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNKTCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKILFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALENENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDESKKKIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFMLLTSEEELEEFELRKFQRSDECLIRLSAVIKTSKKALLQSCNVTVQSCKSLSKVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLAMCNLTVQCCESLSLALQSSNCVLRELDLSNNDLQDSGVKLLSNRLKSQYCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDKLNLDHGGEKRITAGLHKYVCFLTLDPNTAHIQLILSEENRKVKPVREDMMMMRKDQPYPDHPDRFDGLYPQVLCRESVCGCCYWETDWSGDGGVCISVSYKSIRRKGGVECEFGRNAQSWSLHCSSSRFIFIHNNTETRLPVKRLSKRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRVYSGSSVKLS", "length": 1140 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TPE7-1", "protein_name": "Protein NLRC3 isoform X4", "gene_name": "si:dkey-11n14.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKYSVRSGSSSSVSLKSDWSKDEPPKFSEKSPSSARSVEYELPYSGDKTHRSHKGFTKDLPRIFQNLESKIIRYLKNELEKFKKILQEENRQDFVKHFNENRSIITEAALDLTLFFLREMKQDEAADTLEGELFFINQLKCGLKKKYQNVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTTGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKENQSLKDLITQFFPQTKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTKLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISANVLLNILKENRNTELKHRDNSETLHESPKTLTQMYTHFLRFQIQHSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYDSDLKDCGIDVYKASVYSGMCTQIFWEETGIILGTMYCFLHLSIQEFIAALYQHLFLDSDKKHLSIFRQKSKNKVMTDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQNDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSADLSPAQWSAVAFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQGCNLNVRCCESLSSALQSSNCLLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDTLNLNHGGEKRITAGPRKYVCFFTLDPNTANTRLILSKKNREVKCVRENQSYPRHPDRFDDHPQVLCRESVCGRCYWEIDWSGGNEVCISVTYKSIRRKRGYECRFGYNAQSWSLICSSSRFSFTHNDTHTDLPVKPFSRRIGVFVDHCAGTLIFYNIYRDTMSLIHSVQTTFTEPLIPGFWVYSGSSVKLLKTEERFTQNPLQDQ", "length": 1060 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQ28-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:ch211-226o13.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTHTSGDLDLFTSCSVDGDDQTRDLQQDSLQPEHDELQRAKNQHKTSMKNKYERLFEGINHGETQKFLNRIYTQLYIIEGESEGVNREHDVLQIEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQGVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITARPAAAHQIPSTYIHRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDQEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFHCYLTDKREPVMLLYESKYSDDEDVSDGNEYEDSDVQFLQSSSEFSLCHLLSLAIYKAVMSSNGHLDLFLWFLLGVSLESNQRLFQDLLTHTEESSESIRIITQDIKDKIKTDDDLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSERELSPAHCSTISYMIEMSEEPLDELDFNKLNTSPVGRWRLIPAVRNCRRALLQWSYLSVQYCESLFSALKSSNCVLRELDLSTNDLQDSGVKLLSDGLKSPNCKLETLRLQCCNLTAQSCESLTSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCKLETLRLVMCNLTVQCCESLSLALQSSNCVLRELDLSNNGLQDSGVKLLSDGLKSQHCKLDTLRLVMCNLTVQSSESLSSALQSSNCVLRELDLSTNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGLHKYACFLTLDPNTTYAFLILSEENREVKRVREYQQYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDGCSVCTAVSYKSIRRKGRGAECLFGRNAQSWSLCCSSSSFIFRHNYTRTELPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFTVWCQSSVKLC", "length": 1145 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQA8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-29j8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEEQVKDSLSEKQSVRSGSCVSSSVSLKSDNSKGGRTPNFRGKTPSSVKRFFHLGKSKHPPSNLREKTPSSAESFQYELPDSRNKTHRSQKSFRGHLQKIFENLESKIIKFVKKELKNFRKILQNENRQEFVKEFNENSSGITEAALDLTLFFLREMKQDQAADTLQGELLYINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSVVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDTQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVLCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNKVMINLLKTAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQCCNLTVQCCESISSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQQCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGEKRITAGPHKYVCFLTLDPNTAHTRLILSEENREVKCVRENQPYPDHPHRFDYYLQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGAECAFGRNAQSWSLICSSSSFTFRHNNSHTDLTVKPLSRRIGVFVDHSAGTLIFYDIYRDTMSLIHSVQTTFTEPLCPGFYVSYGSSVKLS", "length": 1064 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TTK4-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAMNRLMTDMLEELVEAELKQFTRQLWMGVKPGVDPIPRGKLENKDRQDVVDCMVQHYSKDAGKIAVQALRSIKQNERADRLELNLRKDDDFLGEVLKKHKESIKASVDVFEGKKDNKTDINKVYTELFITEGDMTDVCKEHEVQKFDLALQMPRSEDKPIDCNEIFNLLRGKDKGNVVLTKGIAGIGKTFSVNKFILDWAEGRANLDVDCMFLLPFREINLMIKDGDVSLHKFLLKLFPDITGVETTPFYEKCKLLFIFDGLDESRLDLNFNLSSVDDVHSCASIDGLFTSLIKGRLLRSSLIWVTSRPAAANRIPSYHVGLFTEVRGFTDKQKEEYFRKKVPDEDQASRIISHIRTSRSLYIMCHIPVFCWIIATVLQDILQKNKGEDIPSTLTEMYIHFLLIQMNIKNQKYDEKLIRDRTELLGSNRDMISKLAKLAFEQLKKENVMFYREDLAACGINADEEFTGLCTEIFKKDSVLHELKVYYFIHLSVQEFLAALHVFLCYLELEKDMNLTDSDLMFFLEDSRPKQKELLHVLLRKAIDKAEKSDRGHFDLFLRFLLGISLESNQKLLIGILNETKNSKQSISKTVQYLKQLQNNDKCPDKSINHFFCILELQDRTLYQQIMKYLRSKTNRPKVMSRSNCSALVYVLLMSQEVLDKFNPKLFNKTYAGCRILVPAVRCSRKALFSDCGLTETCFETVALALQLENCPLVELDLSYNYSLEAAVNVMCAGLKSPHCHLESLRLAGCHLGQDSCMQVVSALQSISHRLKELDLSGNDLQDSGLQKLLQGMENTEKRLQVLRLSWCNLTEMSCQQLSTILSSNSVFRELDLSNNDLQDSGVKLLSDGLKSPNCKLKILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHCKLKTLKTDPMGDHLMKPGIVKYAFNLTLNPNTAHVHLLLSDGDRKVTLKEKQPYPDDPERFEEHHQVLSRESLSGRCYWETEWTGQEGTVGVAYESIPRKPDDLLYGRCMLGNNIISWKITCGSRTHVSHAEEDITVKSPSSGSCKRVGVYVDTTAGVLSFYHVFDTLTHLYTFLMPFTQPLYAAFRVDGESVSICPIP", "length": 1114 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TUF4-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch73-236c18.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHHCGNEEVDREEKEKHGAEHSCVSMKSDQSMRNPIAFTDKAVTFDLRSVASSSSHFETHTVQEKTDKGLQTQIFETEELQRVKDQHKTSMRKKYELLSEGIKVKETGTQLNRIYTQLYIIEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFYVFYYHVNTTMMGLKTFASLQKLLKGAVDDAIESKNGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCRLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRIKPGLKKYACFLTLDPNTAHVQIQLSEGNREARNVKDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYCCDTNYTVWYNNESADIIAPSARTNRVGVYLDVSSGSLSFYTVSDANTLTLIHTFNTTFTEPLYTGFGLYPESSVSLCQI", "length": 969 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HUA8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 1 homolog isoform X1", "gene_name": "LOC103910107", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDQDSERAQFVDAHWKTLVQRVIMVMAIADELQSDGMLEWEPYCKIKAAVTNQQKMRELYEVLQSGGDQVKSAFYSSLEKHEPYLLGDLGSIKLMGESLADCLNKYKMWIQKEYEYVTEYNSLPGENVLLSERFTQPLIIMRHRERREREEEMCSVGESFQQLLVSRNNADKDSSILDALFGADSKGISPNSVILQGNSGNGKSFTAQKIMLDWASGKLCKVEFDCLFHLKCKEVNHVSGEQSLTELLSYNSNLTSEQISRILQKSSEKVLILIDGFDELRFSFSDFSDHLKLKDLSEKAPREASLKVLLMGHILSKTSLLVTTRSTATNTLDSLLKHPKRFTEIMGFSEREVKEYFQKFFQDEELFIKAYEYVRSNETLITACSIPVICWIICTVLRERFSEGSDLTSGLETTTSIYVDFVCTLLEHHSQGLSQPVPTLLRSLGQLAERGMLDTQVLFEEKSVDEMVSASPFLCKFLFKRRIRKETMFSFMHLSFQEFFTALYYISQEEREFLDKLTERFHSQTQSYLSLYLDKDFPLKYGCPEPHFLPVVQFLCGLSNSEVSRSLQEMYNLSVPSFVQPQLREWILDMSKSGVYSYLPFILHCLYELHEKEFVQKAMEAWLELDMSWDPLSRTDCWALLYCLDCCPHFRSLKLNFAASELKMLQDVLCRTPKLGLTVQNVSDTDVTVLLSALGEGKQLGELKLNSSCLSDQSVQQVLKALHKQKKVGGLQISVKSITADTALILTDFLQSCSKAEWEEISGSLSTSDVESLCSSLRLFSFEGKLVVNVVRLCLSIQNQPSLSEIILNCPRSEASNIDIKSFTESFHNINCIAEESVDFDRNLHALLTLLTSMSGLSALNLSVPFLTETWASRVLFLVESSPKLTVINFHAGSWCSDGVKWLPGLLLEEGIKLLKESAKRPECIVNIRGFRCSKSSERCSRHTEHIDQLSCNQRVTIQFCGDQCTEDIKLKLVLPDEN", "length": 979 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HZJ9-1", "protein_name": "Uncharacterized protein si:ch211-149a19.3 isoform X1", "gene_name": "si:ch211-149a19.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDKEASNDGDFSSRRSHFQSQKSNTSESNPEITPEDLSAKKLIKMFEKRTPDNQSKFNNQKSNTAKSIRSDRSIQNPVKIKEIRTPADLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPKPMPRSIKSDQSTPELDKVDGGHTSTALSSQRSNPPDPKPRSIKSDQSTPEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGIGCQRSNPPDPKPRSIKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPESSLVSLKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSMPEPIKFDGGHTPTGLSETSTNDQFMNKQVKIKRRHTLTGLSKTSINYQFMEKQLKTERRHTSTGLSLNSKLFENLLKSNLLKKFQCVSEGTSILGNPTLLNEIYTELYITESDSGEINNEHELRQIETQSRRSAKEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEKNKNQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEHYKVLFIFDGLDECRVSLDFDSGVKLHDVSESASVDVLLMNLIMGNLLPSALIWITSRPAAADLIPSGFVHRVTEVRGFNDPQKEEYFRKRIRDQSLADTIISHLKSSRSLHIMCHIPVFCWISATVLEKIFSQAERGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEDKDMILKLGKLAFEQLQKGNLIFYEEDLRECGLDLTEAAVYSGLCTQIFREEFGFSQSKVFCFVHLSIQEHLAALYAHHFLTNNCLNKHWKTFNPLSFLHQRAVNEALQSKNGHLDLFLRFLLGLSLEFNQTLLQELLTQTGSCSYNTEETVQFIKQKIREINSPERSINLFHCLNELGDQSLMKEIQNYLRSGEIKETKLSSSQWSALVYVLLTSEQEMEDFDLNQFIGTQNTADEVLQKLQPVVKESRSVQLSGCSVTDKGCAALALVLRSDSSHLRELDLSENNLRDSGVKLLSDGLKDPHCKLEKLRLSDCGVTDEGCAALASALRSNSTHLTELDLSLNNLEDSGVKLLSDGLKDPHCKLEILRLSDCGVTVEGCADLASALRSNSTHLRELDLTLNNLEDSGVNLLSAGLKDPHCKLEKLRLSDCGFTDEGCADLASALRSNSTHLTELDLSLNNFGDSGVKLLSDGLKDPHCKLEKLRLSYCRVRAEGGVALASALRSNPEHLRELDLSENKLGNSGVKMLSELKNDSRYKLDTLKF", "length": 1375 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCJ8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12-like isoform X1", "gene_name": "si:dkeyp-77c4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKEEHLPNFREKTPPSAQSVRSGSCVSSSVSLKSDWSKRDPPNFREKTPSSAKSSVHQKRAEAEPSCVSMKSDWSMNRPITFRSKITQPAISVDRDDQTGHLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSAQKFILDWAEEKDHQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCALTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQIHMRKQKYEERDPEKLLQSNRGVILKLAEVAFSQLMKGNVMFHEEDLTESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVLYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESTESIRRITQHIKDKIKRDKRLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDELDFNKLNTSAEGRRRLTAAVRNCRRALLQGCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLQWCKPTVQSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLVMCNLTVQCCESLSSALQSSNYVLRELDLSNNDLQDSGVKKLSDGLKSPNCKLETLRLVMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKRNCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKWVCFLTLDPNTAHTQLILSEENREVKRVRENQPYPYHPDRFDVHRQVLCRESVCGRCYWEIDWSGDVGVCISVSYKSIRRKGRGVECWFGYNAQSWSLICSSSRFSFRHNHTDTDLPVEPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFTVYSGSSVKLS", "length": 1235 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCK2-1", "protein_name": "Uncharacterized protein si:dkey-26m3.3 isoform X1", "gene_name": "si:dkey-26m3.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGYVFVLSSLCPVFILLQFLLEFLLEIKLFRSIMGNTHAAGDQDLSTECSSVHQKRAEAEPSCVSMKSDASMGVPITFKSENTGPAVSSVHQKRAEAELSCVSMKSDASMNPPIEFKSGNTGPAVSVDRDGQTGDLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEQIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKDNQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPKLEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTEPSSVAVLMRSLLKGDLLPSALIWITSRPAAAHQIPSTYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLDSNQRLFQDLLTHTEESSENIRRITQYIKDEIKRGKHLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELTPAHCSTISYMIEMSEEPLDELDSNKFNTSDVGRRRLIAAVRNCRRALLQRCELTVQCCESLSSALQSSNCVLRELDLSNNDLQDSAVKLLSDGLKSQHCKLETLRLMTCKLTADSCESLSSALQSSNCVLRELDLSNNDLPDSGVKLLSDGLKSQHCKLETLRLQWCKLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLAMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKTVDCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKYVCFLTLDPNTANTRLILSEENREVKHVRENQPYPDHPDRFDGVYQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGVECWFGSNAQSWSLSCSSSNFSFRHNNTRTDLPVKALNRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRIYPGSSVKLS", "length": 1239 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCL0-1", "protein_name": "Uncharacterized protein si:dkey-165o8.1 isoform X1", "gene_name": "si:dkey-165o8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDQSKDHPPYFREETPSSAESVEYESADPGDETHRRHKSFTDNLQSIFQNLESKIIRFLKNELEKFKKILQEENRKEFIKEFIENRSIITEAALDLTLFFLREMKQDQAADTLQDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNKIYTDLYITQGASEQLNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCGDVSSAVSLDVLLTNLIMGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILRLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLDRNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLDIDKKRGWFLIQISKNKSMIDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQFCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKCRTTHTQTHTHTHTHIHTHTHTHTHIHTHTHTHTHTHTRAHTHTHTRGLQQDRANVGPHTYTHTHTHTHTYTYTHTHTHTHTHTHTHTRITAGPRKCRTTHTHTHTYTHTHTHTITHTHLHIHTHTCTHTHTCAHTHTHIHTHTLTHTRTYTHTHTHTLPLTHTHTHTLSHTHTHTHTNIHTHSLTHTNIHTHSLTHTNKHTHSLSHAYTHACMHALSHLHTHTHALTHTHTHTHTHSLTHTHICTHKHTHTLSHSHKHSHTHTHTHTHTHTHTQARAHLHKHTLSHTHTHIHIYTHTYKHTHILSHTHAHTHTHTQARALTQTYSLTHTHTHTHKHTLSHTHTHIHHTHTQIHIHSHKTHTHARTHTLSLSLTHTHTHTHTHTHTHTHTHTHTHTQLWL", "length": 1266 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JD10-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch211-203c5.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVGYDTECSVCVVCSRMLVCVCVVHLRCSMAEERVKDSLSEKHSVRSGSCVSSSVSLKSDWSKGNPPQFSGESPSSAQSVEYESADSGDETHRRHKSFTDNLQSIFQNLESKMIRFLKNQLEKFKKILQEENRQEFVKEFNENRSIMTEAALDLTLFFLREIKQDQAADTLQDELLYINQLKCSLKKKYQRVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCHDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESSKTLTQMYTHFLRFQIQQSRKKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDRDKKHGLFLQIGKNKGVTDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKKKIIAYIKQKLKGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGRLSSARLSPAQWSALVFVLLTSEEELEEFELHKFQRSDECLIRLSAVIKTSKRALLQSCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPHKYVCFLTLDPNTAHTRLILSEENREVKRVRENQPYPDHPDRFDGYVYPQVLCRESVCGRCYWEIDWSGDDGVFISVSYKSIRRKGGGVECWFGCNAQSWSLLCDSSSFSFRHNNTLTDLPVEALSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCAGFGFSSGSSVKLS", "length": 1073 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z7N0-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Dmel\\CG8197", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCDVLLPCEYNPKECPSPAAEKSRLFTILLLYCWQREYDKRPYRQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLRRPQLSVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPREFFVMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANRLLGMSLSLDTEKISSVLSSLLMQNTLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLAMKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISYTYDEALQDYRVVPWR", "length": 387 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZAD9-1", "protein_name": "NLR family, pyrin domain containing 9", "gene_name": "Nlrp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDTSGYGLLKHLRKLSDGEFWSFKELLRKEPEKFKLKPISWMKIENASKEELVMLLNTHYPKQAWDMALSLFLQVNREDLSIMAQKKRRYKQTKYKKFMKTTFQSIWTLESNICIPDRSYHLIVEHQYRKLQNIFDSESEPVTAVVTGPTGEGKTVFLRKAMLDWASGILWQNRFQYVFFFSVLSLNNTTELSLAELISSKLPESSETLNDILSDPKKILFILDGFDYLKFDLELRTNLCNDWRKILPTQIILSSLLQKIMLPESSLLLELGHISLPKIFPLLQYPRDITIQGFSERCLKTYFISFFNTEKGIEVFENLKSNQMLKLCSNPYLCWMFCSCLKWQFDREEEAYFQAKTDSVFFTSFMVSAFKSAYASNPPKQNRAQLKSLCTLAVEGMWKQLFVFDSEDLRRNGISESDKAVWLRMKFLQNHDNHIVFYHPTLQLYFASMFYFLKQDKDTHVPVIGSIPQLLRKIYARDHTQWLQIGIFLFGLATEQVASLLKPYFGFIQHRDVRQEVMRYLKSLSQRECCEKLERPQNLFACLRDNKEEKFVREVVDLFEEITVDITNSHVLSIIANHLQKSSKLKKLHLHIQKRVFLEIHDPEYSDSETFTQDKKNAAEYWKKLCHIFVNLHVLDLDSCNFNKQVIEELCNVLSPSPKIPLMAFKLESLLCSFMTNFGDGSLFHTLLQLPHLKYLNLYGTNLSNSRIENLCSALRRSTCKVEELLHSEMSFPLSTDFIVSHKFGLGKCDISSEACGIIATSLMNSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLETLMLSYCCLTFIACGHLYEALVSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCILKELWLSGCFLTSECCEEISAVLTCNNNLKTLKLGNNDIEDTGVKHLCEALSHPNCKLECLGLDLCKFTSDCCEDLASALTTCKTLNSLNLDWKTLEHSGVVALCEALNHKKCNLKMLGLDKSAFSVESQTLLQAVEKKNNNLSILHYPWVEEERKKRGVRLVWNSKN", "length": 1022 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZP31-1", "protein_name": "NLR family, pyrin domain containing 4", "gene_name": "Nlrp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEILQLRLKQISWTKVKKASREDLANLLLKHYEEKQAWDMTFKIFQKMNRKDLIERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKAQDLFKQKFTQDDCDRFENLLVSKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGIVFQNKFSYIFYFCCQDVKQLKRASLAELISREWPNASAPTAEILSQPEKLLFIIDSLEVMECNMSERESELCDNCTEKQPVSLLLSSLLRRKMLPESSFLISATPETFEKMEDRIECTNVKIITGFNENNIKMYFRSLFQDKNRTLEAFSLVRENEQLFNVCQVPVLCWMVATCIKKEIEKGRDPVFICRRTTSLYTTHIFNLFTPQNAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFSEEALRRNGILDSDIPTLLDRRILERSKESESCYIFLHPSLQEVCAAVFYLLKSHLDHPSQDVKSVEALLFTFLKKAKVQWIFLGCFLFGLLHESEQEKLEMFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEAFLMQAMNCMEQINFVAKDYSDVIVAAYCLKHCSTLKKLSFSTQNILSEEQEHSYTEKLLICWHHMCSVLISSKDIHVLQVKDTNLNETAFWVLYNHLKYPSCTLKVLVVNNVTFLCDNHLFFELIQNQRLQHLNLSLTFLSHSDVKLLCDVLNQAECNIEKLMIAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLCKALCHPDCILKHLVLANCSLSEQCWDYLSEVVRRNKTLSHLDISSNDLKDEGLKVLCGALTLPDSGLISLSVRHCLITTSGCQDLAEVLRHNQNLRSLQVSNNKIEDAGVKLLCDAIKQPNCHLENIGLEACELTGACCKDLASAFVHCKTLWGINLLENALDHSGLVVLFEALKQQKCTLHVLGLRITDFDKETQEFLIAEEEKNPYLSILSNV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZUH1-1", "protein_name": "NLR family, pyrin domain containing 4A", "gene_name": "Nlrp4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLGLKQVSWTEVKKASREDLASLLLKHYEEKQAWDMTFNFFQKINRKDLIKRAKREIDGYPKLYRAHLKTKLTHDSSRIFNINIQDFLKEKFTKDDHDRFETLLQSKGTESKPQVVVLSGVAGIGKTLMLKRLMLAWIEGLVFPYKFSYIFYFCCQEVKQLKTASLAELISREWPDPSAPIEEILSEPEKLLFIIDSLEGIECDLFKCDSELCDNCMEKQPVNILLSSLLRKKMLLEASLLISTTPETFEKMEDRIEYTHVKIITGLNESDIKMCFHRLFQDRNRAQEAFSLVRENEQMLTICQVPVLCWMVATCLKTEIEKGRNLVSTCRRTTSLYTTYIFNLFIPQSAHSPSKKSQDQLQGLCSLAAEGIWTDTFVFTEEALRRNGILDSDIPTLLDIGMLGKMGKFENCYIFLHPSLQEACAAIFYLLKSHGDHPIEDVKSVEALLFTFLKKAKVQWILGGRFIFGLLHESEQKKLEAFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEDFLMEAMNYMEQINFVAKDYSDVIVAAYCLKHCYTLKKLSFSTQNILNEEHEHSCMENLLTCWRHICSVLINSKDIQELQIKDTNLNEPAFSVLYNSLKYCNDTLKVLVENNVFFLCEKYLFFELIQNCNLQHLNLNLTFLSHSDVKLLCDVLNQAECNIEKLEVAACNLSPDDCKMFASILMSSKTLKQLNLSSNILGKGISSLCKSLCHPDCILEHLVLAKCSLSDQCWDYLSDGIRQNKTLNHLDISSNDLKDEGLKVLCRALALPNSVLKSLCLRHCLITTSGCQDLAEVLRNNQNLTSLQISYNKIEDAGVKLLCDAIKQPNCHLEDLGLEACELTGACCEDLASTFTQCRTLWGINLLNNTLDYTGLVVLCEALRQQKCTPHVLGLRITDFDNETQAFLVAEQEKNPDLSILSGV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A1P8-1", "protein_name": "NLR family, pyrin domain containing 4B", "gene_name": "Nlrp4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLFSDFGFMWYWKELNKVEFMKFKELLILEILQMGLKQISWTEVKNASREDLAILLVKYCEGKQAWDTTFKVLQKISRHDLTERATGEIAAHANIYRAHLKKKLTRDCSRKFSISIQNFFQDEYDHLENLLIPKVTEEKPQLVFLKGIAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCQDVKQLKTTSLTELISREWPSSSAPIEEILSQPEKLLFIIDSLEGMEWDFTKQESELCDNCLEKQPVNVLLSSLLKKKILPESSLLISATFETFEELKDWIEYTNVRTITGFKESNIKMYFHSLFQDRNRALEAFSFVRENEQLFTLCQAPVICCMVATCLKNEIEKGKDPVSICRRTTSLYTTHIFNLFIPPNVQYPSKKSQDQLQGLCFLAVEGMWTDISVFSEETLRRNGILDSDIPTLLDIGILEQSRESQNSYIFFHPSVQEFCAAMFYLLQTHMNHPSPDVLHVEKLLFSFLKEVNTQWIFLGRFIFGLLNELEHEKLEAFFGYQLSQQLKQELFEWLELLLDPEVKVNTMKFFYCLFEMEEEVFVQSAMNCREEIDVVAKDYYDFIVAAYCLNHGSALRDLSISTQNVLNEKLNQRYMENLLMLWHNICSVFARNKDIHILQMKDTIFNEPVFQILYNYLKNSSCILEVLVANDVSFLCDKYLFFDLIQSYNLELLDLSGTFLSHSDVVILCNILNKAEYKIQELELANCSLSEQSWKYISDVLCQNKTLRHLDISSNDLKDEGLKVLCKALTLPDSVLLTLSVKACFITTVGCQYLAEVLRNNHKLMFLTLSENKLEDSGVKLLCDAIKHPRCQLAQLDLEACELTGACCEDLASTFTQCKTLGWINLVKNALDFNGLVVLCKALKQKTSNLKELRLRITDFDNKSQTFLLSEEKGNKFLNIENDE", "length": 918 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A523-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWNDACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGRTKMWDRPMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEEEEKRGSQPLDQVQCVFPDPHVACSSRLVNCCLTSSFCRGLFSSLSTNQSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSSQKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTNQNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNCETKRTLEALQEEKPELTVVFEISW", "length": 1035 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FA88-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "nlrc11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYCNYNMDNTRSSRDEDIYSCTSRESEEVLSNTSYWSLPSYFRHRKFHRSSVHEKISDSSESSRVSLKSDWSMNPPPLLGEERKSSNLNMSSLVSVRSDWSMDPPPLLRAKGKSAVSSGVSDNIDWLVCSPYLRVERKSSALRHKLSLLKKFQCLYEGTAVQGKPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLIKDKKFSLVSLLQTFFTREIHLDMIQNSAVIFIFDGLDECRLPFNFSRNEILLDVTKETSVDVLLTNLIVGNLLPYALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILRLGKLAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLLFTNHNINVFEQMTKSFEGTPLNKSDLQSLTLNMELFEISEPVLTDVAAMCEMDWRVVNEISALHCKAVDEVLQNKNGHLDLFLRFLLGLSVECNQILLQRLTKQRRHLYNDNKTVEYIKKKIRTINSPEKSISLFHCLNELGDHSLVEEIQQYLTSGKIKEFKLSSSQWSAVAFVLLTSEKKLEEFWLKEFVGAETKADHVLQKLLPVVKESRKAELSKCGLTEECCAALASALRSKLSHVRELDLSGNKLGDSGIENLSTGLENLHCKLEILRLRSCGITAKGCTALASALRSNPEQIRQLDLSENNIRDWGVKHLFTELKNPDCKLEILGLRNCGITIEGCAALTSALIINPSHLRELDISRNSLGDTGQELLTSLLNSQHHKLEILLLHKFPMTFTSLPSSHSPEMFPQRFRTHNLKE", "length": 966 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q5R7-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSTARDGLYRLSTYLEELEAGELKKFKLFLGIAEDLSQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGEDLVRVTPNNGLCLFESQSACPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPEPPHTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGPWCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTPRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFAAMYCALNGREAVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWSISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQVVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGSAYSTGMEDDPPEPSGVQTQSTYLQERNMLPDVYSAYLSAAVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISGSACQDLAAAVIANRNLIRLDLSDNSIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLSNNSYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVNTCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGISQTLHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFGMDLNKKTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M918-1", "protein_name": "NLR family, pyrin domain containing 14", "gene_name": "Nlrp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTEDEEMEDQLSKEEIVSEDKEFDYRTIIKENFFIIWDKTSLLGESATLNCVTTHKDQKLLEHIFDVNIQTSKSPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLSGREISQEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFALCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMTCQTSTALFTYYICSLFPRIAGSSVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQDTECENCYTFTHLQVQEYFAALFYLLRENPEEKDHPLEPFENVHLLLESNHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLTISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVKVDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDPTAEICLEDAAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLNSCYDFSFLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQSNRSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTKTKRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNNKSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNNSNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNNQSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCPNTESGCWWQYF", "length": 990 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RA38-1", "protein_name": "NLR family pyrin domain containing 2", "gene_name": "Nlrp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHSDQLGFNLKDVLKKLDKTELNNFKSTLKSCSLPQTMKQISKLTMDLANGAQLAEILTDYCPNDWVKRVTFKILEEINRADLAELVMKQVEEAASKASEEKVSSKPREPLKTSLFPQDFVQGDERPEHKHKKEWRNMYTEKWKKNFWPKCNKEIYVDTESYRTLLTLCNPKIEMPFAYTIVLHGPPGSGKTTMARRLMLEWSESKQAQSFSCAFYISCRKLNNSKPCTFAHLLSMNNPSWRYYMIRRLVLSEQFLFVVDGFDELTFPAGALLRDICGDWNTVKPVEVLLSSLLMRKMEPHSTLLVTTQTQSLHQIYLMVDQPVLVETQGFLEPEKQEYFQQYFEDEEGEEEGEGEGKALRALKEVKCNEALFQMASLPAACGIFCLCLELGMKKGEDLALTCQTYTSMFLNFLCRVFLQEACDGHLNKQLQILFKKICILAADSLLEQVPILCEEDFLKLKLNLNKLHPVVYRCIFLEDSSCTNCLSFICLSIQQLLAAIIFVQELGQESKDVSKYSIQKMLSREARLKNPNLSGVLPFVFSLLNKTHIQELETIFGCQISMGVKRKFLECELGENKPFLLLMDLQEIFSCLYESQEEEFVKEAMALFGEVSLHLKTNMDLVHASFCLKNSQNLQTMFLKVEKAVFPENFATLESTAEDQRFQDKKCMLTLWTDFCDTFHSNEKLAFLEIHESFLNSSSLEILCEKLSSAPCHLQKVVLKNISPDDAYEKLCLIFCGYETISHLTLQGGKLDSMLHSLCKVVKNPACNLKFLSLGSCSTTAQKWDDFFPALKANQSLISLDLTDNNLLDKGVRLLCNTWKQSKCILQRVSLENCHLTEVCCKDLSSVLMVSQTLTHLSLAKNELGDNGVKKLCESLSFPKCKLQTLVLWSCNITSNGCHYLSKMLGQAPSLKHLDLGLNRIGTTGAKFLCEALKSPRSNLKSLWLCGCSIIPTNCKDFSEILRSNKSLNTLDLSQNVMGTDAVKIFCESLKLQICPLQTLRLKFDEANPSIQKLIQEMKESHPQLSITSDQVDPKKKSHSFPHFIF", "length": 1048 }, "evidence": [ { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13489-1", "protein_name": "Ribonuclease inhibitor", "gene_name": "RNH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEARCKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGAGCGVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRDLCGIVASKASLRELALGSNKLGDVGMAELCPGLLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEGARLLCETLLEPGCQLESLWVKSCSFTAACCSHFSSVLAQNRFLLELQISNNRLEDAGVRELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAATLLANHSLRELDLSNNCLGDAGILQLVESVRQPGCLLEQLVLYDIYWSEEMEDRLQALEKDKPSLRVIS", "length": 461 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59044-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 6", "gene_name": "NLRP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGPDGRSIPWGRLERADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSEYKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQPQRLLFILDGADELPALGGPEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRLQGRLCSPQCAEVRGFSDKDKKKYFYKYFRDERRAERAYRFVKENETLFALCFVPFVCWIVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAREGVLGRRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAALSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLVLTTRFLFGLLSAERMRDIERHFGCMVSERVKQEALRWVQGQGQGCPGVAPEVTEGAKGLEDTEEPEEEEEGEEPNYPLELLYCLYETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLISCRLVAAQEKKKKSLGKRLQASLGGGSSSQGTTKQLPASLLHPLFQAMTDPLCHLSSLTLSHCKLPDAVCRDLSEALRAAPALTELGLLHNRLSEAGLRMLSEGLAWPQCRVQTVRVQLPDPQRGLQYLVGMLRQSPALTTLDLSGCQLPAPMVTYLCAVLQHQGCGLQTLSLASVELSEQSLQELQAVKRAKPDLVITHPALDGHPQPPKELISTF", "length": 892 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59045-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 11", "gene_name": "NLRP11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESDSTDFDLLWYLENLSDKEFQSFKKYLARKILDFKLPQFPLIQMTKEELANVLPISYEGQYIWNMLFSIFSMMRKEDLCRKIIGRRNRNQEACKAVMRRKFMLQWESHTFGKFHYKFFRDVSSDVFYILQLAYDSTSYYSANNLNVFLMGERASGKTIVINLAVLRWIKGEMWQNMISYVVHLTAHEINQMTNSSLAELIAKDWPDGQAPIADILSDPKKLLFILEDLDNIRFELNVNESALCSNSTQKVPIPVLLVSLLKRKMAPGCWFLISSRPTRGNNVKTFLKEVDCCTTLQLSNGKREIYFNSFFKDRQRASAALQLVHEDEILVGLCRVAILCWITCTVLKRQMDKGRDFQLCCQTPTDLHAHFLADALTSEAGLTANQYHLGLLKRLCLLAAGGLFLSTLNFSGEDLRCVGFTEADVSVLQAANILLPSNTHKDRYKFIHLNVQEFCTAIAFLMAVPNYLIPSGSREYKEKREQYSDFNQVFTFIFGLLNANRRKILETSFGYQLPMVDSFKWYSVGYMKHLDRDPEKLTHHMPLFYCLYENREEEFVKTIVDALMEVTVYLQSDKDMMVSLYCLDYCCHLRTLKLSVQRIFQNKEPLIRPTASQMKSLVYWREICSLFYTMESLRELHIFDNDLNGISERILSKALEHSSCKLRTLKLSYVSTASGFEDLLKALARNRSLTYLSINCTSISLNMFSLLHDILHEPTCQISHLSLMKCDLRASECEEIASLLISGGSLRKLTLSSNPLRSDGMNILCDALLHPNCTLISLVLVFCCLTENCCSALGRVLLFSPTLRQLDLCVNRLKNYGVLHVTFPLLFPTCQLEELHLSGCFFSSDICQYIAIVIATNEKLRSLEIGSNKIEDAGMQLLCGGLRHPNCMLVNIGLEECMLTSACCRSLASVLTTNKTLERLNLLQNHLGNDGVAKLLESLISPDCVLKVVGLPLTGLNTQTQQLLMTVKERKPSLIFLSETWSLKEGREIGVTPASQPGSIIPNSNLDYMFFKFPRMSAAMRTSNTASRQPL", "length": 1033 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59046-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "NLRP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQSTCLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELKPSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEGEGGAGPDQDVTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSAGAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIANKNLTRMDLSGNGVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC", "length": 1061 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 5", "gene_name": "NLRP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVAGGLELGAAALLSASPRALVTLSTGPTCSILPKNPLFPQNLSSQPCIKMEGDKSLTFSSYGLQWCLYELDKEEFQTFKELLKKKSSESTTCSIPQFEIENANVECLALLLHEYYGASLAWATSISIFENMNLRTLSEKARDDMKRHSPEDPEATMTDQGPSKEKVPGISQAVQQDSATAAETKEQEISQAMEQEGATAAETEEQEISQAMEQEGATAAETEEQGHGGDTWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDSDRWGFRPRTVVLHGKSGIGKSALARRIVLCWAQGGLYQGMFSYVFFLPVREMQRKKESSVTEFISREWPDSQAPVTEIMSRPERLLFIIDGFDDLGSVLNNDTKLCKDWAEKQPPFTLIRSLLRKVLLPESFLIVTVRDVGTEKLKSEVVSPRYLLVRGISGEQRIHLLLERGIGEHQKTQGLRAIMNNRELLDQCQVPAVGSLICVALQLQDVVGESVAPFNQTLTGLHAAFVFHQLTPRGVVRRCLNLEERVVLKRFCRMAVEGVWNRKSVFDGDDLMVQGLGESELRALFHMNILLPDSHCEEYYTFFHLSLQDFCAALYYVLEGLEIEPALCPLYVEKTKRSMELKQAGFHIHSLWMKRFLFGLVSEDVRRPLEVLLGCPVPLGVKQKLLHWVSLLGQQPNATTPGDTLDAFHCLFETQDKEFVRLALNSFQEVWLPINQNLDLIASSFCLQHCPYLRKIRVDVKGIFPRDESAEACPVVPLWMRDKTLIEEQWEDFCSMLGTHPHLRQLDLGSSILTERAMKTLCAKLRHPTCKIQTLMFRNAQITPGVQHLWRIVMANRNLRSLNLGGTHLKEEDVRMACEALKHPKCLLESLRLDCCGLTHACYLKISQILTTSPSLKSLSLAGNKVTDQGVMPLSDALRVSQCALQKLILEDCGITATGCQSLASALVSNRSLTHLCLSNNSLGNEGVNLLCRSMRLPHCSLQRLMLNQCHLDTAGCGFLALALMGNSWLTHLSLSMNPVEDNGVKLLCEVMREPSCHLQDLELVKCHLTAACCESLSCVISRSRHLKSLDLTDNALGDGGVAALCEGLKQKNSVLARLGLKACGLTSDCCEALSLALSCNRHLTSLNLVQNNFSPKGMMKLCSAFACPTSNLQIIGLWKWQYPVQIRKLLEEVQLLKPRVVIDGSWHSFDEDDRYWWKN", "length": 1200 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TKR3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4C", "gene_name": "Nlrp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLRLKQISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRKDLMERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKVQDFSKQKFTQDDYDRFENFLISKVTAKKPHMVFLQGAAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPKTSAPIEDILSQPEKLLFVIDNLEVMECDMSERESELCDTCTEKQPVRILLSSLLRRKMLPKSSFLISATPETFEKMEGRVECTNVKIVTGFNESNIKMYFRSLFQDKTKTQEIFSLVKENQQLFTVCQVPVLCWMVATCLKKEIEKGRDLVSVCRRTTSLYTTHIFNLFIPQSAQYPSKESQAQLQSLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPTLLDVRILEKSKKSEKSYIFLHPSIQEVCAAIFYLLKSHMDHPSQDVKSIEALIFTFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQVDGMKLFYCLFEMDDEAFLAQAMNCMEQINFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNVLSEGQEHSYTEKLLMCWHHMCSVLISSKDIYILQVKNTNLNETASLVLYSHLMYPSCTLKALVVNNVTFLCDNRLFFELIQNQCLQHLDLNLTFLSHGDVKLLCDVLSQEECNIEKLMVAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLVNCSLSEQCWDYLSEVLRRNKTLNHLDISSNDLKDEGLKVLCGALSLPDSVLKSLSVRYCLITTSGCQDLAEVLRKNQNLRNLQVSNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASAFTHCKTLWGINLQENALDHSGLIVLFEALKQQQCTLHVLGLRITDFDKETQELLMAEEEKNPHLSILSSV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X03-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9A", "gene_name": "Nlrp9a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDSSGYGLLQYLQKLSDEEFQRFKEHLRKEPEKFKLKPISWTKIKNTSKEDLVMQLYTHYPGKAWDMVLSLFLQVNREDLSTMAQTERRDKQTKYKEFMKNTFQHIWTMETNTYIPDRSYHEFIEVQYRALQDIFDCESEPVTVVVSGSRGGGKTTFLRKAMLDWASRNLLQNRFQYVFHFSVFSLNNITELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKKLPIQIVLSSLLQKIMLPECSLLLELGNASLSNIIPLLQYPREIIMSGFSEQTIEIYCVSFFNTQTGVEIFKNLKSIKPLFNLCRCPHLCWMICSTIKWQYERREVASRFGRTLGLLYTIFMVSAFKSTYARNPSKQNRARIRTLCTLAVEGMWKQVYVFDSDDLRRNGISESDKKVWLRMKFLQNQGSNIVFYHSTLQWYFAVLFYFLQYKDTRHPVIGNLAQLLGEIYAHKQNQWFHTRILLFGMATEQVNSLLEPCFGCISSKEVRQEIIRYIKSLSQQECNEKLVVHPQNLFFCILDNQEERFVRQLMDRFEEMTVDISDVDDMSATPYCLHRAPKVKNLHLHIQKRVFLEIHDPEYGDLELFKLGQKCSFTTNFGDGLLFCTFLHLPHLKYMNLYGTNLSNDAVERLCSALKFSTCGVEELLLGKCDISSEACGIIAASLINSEVKHLSLVENPLKNKGVMSLCEMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNEHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCYLTSECCEEISAVLTCNTNLKTLKLGNNNIQDTGVKRLCEALCHPNCEMQCLGLDMCDFTSDCCEDLALVLTTCNTLKSLNLDWNAFDHSGLEMLCKALNHKACNLEVLGLDKSLFSEESQTLLQAVEKKNKNLKVLHFPWLKEELEKRGVRLVWNSKN", "length": 949 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X05-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4F", "gene_name": "Nlrp4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFISDFGLIWYLRELNKKEFMKFKDFLIQEILELKLKQVSSTKVKKASREDLANLLLKCGENQAWDMTFRILQKINRKDLTERATGAIVGNPNLYRDHLKKKLTHDCPKKFNVRIQDFIKETFIQNDXDAFENLLISKGTERKPHMVFLKGMAGVGKTLMLKNLMLAWSKGLVFQNKFSYAFYFCCQDVKQLKTASLAELISREWPSPSAPIEEILSQPEKLLFIIDSLEGMEWDLTKQESELCDDCMEKQPVSTLLSSLLRRKMLPESSLLLSTTPETFEKMEDRIQCTDVKTATAFDERSMKIYFHRLFQDRKRAQEAFSLVRENKQLFTICQVPLLCWMVATCLKEEIEKGGDPVSLCRRTTSLYTTHIFSLFIPQSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFGKEALRRNGIFDSDIPTLLDIGMLGKIREFENSYIFLHPSVQEVCAAIFYMLKRHVEHPSQDVKNIETVLFMFLKKVKTQWIFLGCFIFGLLQKSEQEKLGVFFGHRLSKNIHHKLYQCLETLSGNAELQEQIDGMRLFSCLFEMEDEAFLVKAMNCMQQINFVAKNYSDFIVAAYCLKHCSTLKKLSFSTENVLNEGDQSYMEELLICWNNMCSVFVRSKDIQELRIKDTNFNEPAIRVLYESLKYPSFTLNKLVANNVSFGDNHVLFELIQNSSLQYLDLSCSFLSHNEVKLLCDILNQAECNIEKLMIAHCKLSPDDCKIFGSILMSSKSLKVLNLASNNLNQGISSLCKALCHPHCTLEYLVPRSNHCIVNFLLKLSCCGITERGCQDLAEVLKNNQNLKYLHVSYNKLKDTGVMLLCDAIKHPNCHLKDLQLEACEITDASNEELCYAFMQCETLQTLNLMGNAFEVSRMVFFPRKSELMLFIFLHLSRLWITDFDNEFQAFLLSVKKKNHFLTIRGSVEADGEKKGGDSDARTMGELSNEI", "length": 959 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X19-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4E", "gene_name": "Nlrp4e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKELLQQEILQLGLKHISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRQDLMERAGREIAGHSKLYQVHLKKKLTHDYARKFNIKDQDSLKQKFTQDDCDHFENLLISKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPNASAPIEEILSQPEKLLFVIDNLEVMECDMSEWESELCDDCMEKQPVNILMSSLLRRKMLPESSFLVSATPETFEKIEDRIECTNVKMMAGFNESSIKVYFYSLFQDRNRTQEIFSLVRENEQLFSVCQVPVLCWMVATCLKKEIEKGRDPVSICRRITSLYTTYIFNLFIPHSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFAEEALRRNGIMDSDISTLLDVRILEKSKESEKSYIFLHPSIQEVCAAIFHLLKSHVDHPSQDVKSIEALIFTFLKKVKIQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNKELQEQIDGMKLFYCLFEMDDEAFLPQVMNCMEQIKFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNILSEGQEHSYTEKLLICWHHVCSVLTSSKDIHVLQVKDTNFNERAFLVLYSHLKYPSCILKVLEVNNVTLLCDNRLLFELIQNQRLQLLNLSLTFLSHNDVKLLCDVLNQAECNIEKLMVADCNLSPDDCKVFVSVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLAKCSLSEECWHYLSEVLRRNKTLTHLDISFNDLKDEGLKVLCGALTLPDSVLISLSVRYCLITTSGCQDLAEVLRNNQNLRNLQISNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASSFTHCKTLLGINLQENALDHSGLVALFEAMKQQQCTVNLRGLRITDFDKETQEFLMAEKEKNPYLSI", "length": 978 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X22-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9B", "gene_name": "Nlrp9b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSSGYGLLKLLQKLSDEEFQRFKELLREEPEKFKLKPISWTKIENSSKESLVTLLNTHYPGQAWNMMLSLFLQVNREDLSIMAQKKKRHKQTKYKKFMKTTFERIWTLETNTHIPDRNYHLIVEVQYKALQEIFDSESEPVTAIVAGTTGEGKTTFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKRLPTQIVLSSLLQKIMLPGCSLLLELGQISVPKIRHLLKYPRVITMQGFSERSVEFYCMSFFDNQRGIEVAENLRNNEVLHLCSNPYLCWMFCSCLKWQFDREEEGYFKAKTDAAFFTNFMVSAFKSTYAHSPSKQNRARLKTLCTLAVEGMWKELFVFDSEDLRRNGISESDKAVWLKMQFLQTHGNHTVFYHPTLQSYFAAMFYFLKQDKDICVPVIGSIPQLLGNMYARGQTQWLQLGTFLFGLINEQVAALLQPCFGFIQPIYVRQEIICYFKCLGQQECNEKLERSQTLFSCLRDSQEERFVRQVVDLLEEITVDISSSDVLSVTAYALQKSSKLKKLHLHIQKTVFSEIYCPDHCKTRTSIGKRRNTAEYWKTLCGIFCNLYVLDLDSCQFNKRAIQDLCNSMSPTPTVPLTAFKLQSLSCSFMADFGDGSLFHTLLQLPHLKYLNLYGTYLSMDVTEKLCAALRCSACRVEELLLGKCGISSKACGIIAISLINSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLQSLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCFLTSQCCEEISAVLICNRNLKTLKLGNNNIQDTGVRQLCEALSHPNCNLECLGLDLCEFTSDCCKDLALALTTCKTLNSLNLDWKTLDHSGLVVLCEALNHKRCNLKMLGLDKSAFSEESQTLLQDVEKKNNNLNILHHPWFEAERNKRGTRLVWNSRN", "length": 1003 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6B966-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "Nlrp14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTEDDEMEYEASKEETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITPKDQNLLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLNGKEISQVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFALCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVGCVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQDTEYENCYMFTHLHVQEFFAALFYLLRENLEEQDYPSEPFENLYLLLESNHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVRVDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLDTAEMCLEGAAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLNGCQDFTFLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTKSKRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHNRSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNNSNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNNKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECPNTESGCWWNYF", "length": 993 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTR0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9", "gene_name": "NLRP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESFFSDFGLLWYLKELRKEEFWKFKELLKQPLEKFELKPIPWAELKKASKEDVAKLLDKHYPGKQAWEVTLNLFLQINRKDLWTKAQEEMRNKLNPYRKHMKETFQLIWEKETCLHVPEHFYKETMKNEYKELNDAYTAAARRHTVVLEGPDGIGKTTLLRKVMLDWAEGNLWKDRFTFVFFLNVCEMNGIAETSLLELLSRDWPESSEKIEDIFSQPERILFIMDGFEQLKFNLQLKADLSDDWRQRQPMPIILSSLLQKKMLPESSLLIALGKLAMQKHYFMLRHPKLIKLLGFSESEKKSYFSYFFGEKSKALKVFNFVRDNGPLFILCHNPFTCWLVCTCVKQRLERGEDLEINSQNTTYLYASFLTTVFKAGSQSFPPKVNRARLKSLCALAAEGIWTYTFVFSHGDLRRNGLSESEGVMWVGMRLLQRRGDCFAFMHLCIQEFCAAMFYLLKRPKDDPNPAIGSITQLVRASVVQPQTLLTQVGIFMFGISTEEIVSMLETSFGFPLSKDLKQEITQCLESLSQCEADREAIAFQELFIGLFETQEKEFVTKVMNFFEEVFIYIGNIEHLVIASFCLKHCQHLTTLRMCVENIFPDDSGCISDYNEKLVYWRELCSMFITNKNFQILDMENTSLDDPSLAILCKALAQPVCKLRKLIFTSVYFGHDSELFKAVLHNPHLKLLSLYGTSLSQSDIRHLCETLKHPMCKIEELILGKCDISSEVCEDIASVLACNSKLKHLSLVENPLRDEGMTLLCEALKHSHCALERLMLMYCCLTSVSCDSISEVLLCSKSLSLLDLGSNALEDNGVASLCAALKHPGCSIRELWLMGCFLTSDSCKDIAAVLICNGKLKTLKLGHNEIGDTGVRQLCAALQHPHCKLECLGLQTCPITRACCDDIAAALIACKTLRSLNLDWIALDADAVVVLCEALSHPDCALQMLGLHKSGFDEETQKILMSVEEKIPHLTISHGPWIDEEYKIRGVLL", "length": 991 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W24-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "NLRP14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSSSSSFFPDFGLLLYLEELNKEELNTFKLFLKETMEPEHGLTPWNEVKKARREDLANLMKKYYPGEKAWSVSLKIFGKMNLKDLCERAKEEINWSAQTIGPDDAKAGETQEDQEAVLGDGTEYRNRIKEKFCITWDKKSLAGKPEDFHHGIAEKDRKLLEHLFDVDVKTGAQPQIVVLQGAAGVGKTTLVRKAMLDWAEGSLYQQRFKYVFYLNGREINQLKERSFAQLISKDWPSTEGPIEEIMYQPSSLLFIIDSFDELNFAFEEPEFALCEDWTQEHPVSFLMSSLLRKVMLPEASLLVTTRLTTSKRLKQLLKNHHYVELLGMSEDAREEYIYQFFEDKRWAMKVFSSLKSNEMLFSMCQVPLVCWAACTCLKQQMEKGGDVTLTCQTTTALFTCYISSLFTPVDGGSPSLPNQAQLRRLCQVAAKGIWTMTYVFYRENLRRLGLTQSDVSSFMDSNIIQKDAEYENCYVFTHLHVQEFFAAMFYMLKGSWEAGNPSCQPFEDLKSLLQSTSYKDPHLTQMKCFLFGLLNEDRVKQLERTFNCKMSLKIKSKLLQCMEVLGNSDYSPSQLGFLELFHCLYETQDKAFISQAMRCFPKVAINICEKIHLLVSSFCLKHCRCLRTIRLSVTVVFEKKILKTSLPTNTWDGDRITHCWQDLCSVLHTNEHLRELDLYHSNLDKSAMNILHHELRHPNCKLQKLLLKFITFPDGCQDISTSLIHNKNLMHLDLKGSDIGDNGVKSLCEALKHPECKLQTLRLESCNLTVFCCLNISNALIRSQSLIFLNLSTNNLLDDGVQLLCEALRHPKCYLERLSLESCGLTEAGCEYLSLALISNKRLTHLCLADNVLGDGGVKLMSDALQHAQCTLKSLVLRRCHFTSLSSEYLSTSLLHNKSLTHLDLGSNWLQDNGVKLLCDVFRHPSCNLQDLELMGCVLTNACCLDLASVILNNPNLRSLDLGNNDLQDDGVKILCDALRYPNCNIQRLGLEYCGLTSLCCQDLSSALICNKRLIKMNLTQNTLGYEGIVKLYKVLKSPKCKLQVLGLCKEAFDEEAQKLLEAVGVSNPHLIIKPDCNYHNEEDVSWWWCF", "length": 1093 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W25-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 13", "gene_name": "NLRP13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFSVITCPNGGTNQGLLPYLMALDQYQLEEFKLCLEPQQLMDFWSAPQGHFPRIPWANLRAADPLNLSFLLDEHFPKGQAWKVVLGIFQTMNLTSLCEKVRAEMKENVQTQELQDPTQEDLEMLEAAAGNMQTQGCQDPNQEELDELEEETGNVQAQGCQDPNQEEPEMLEEADHRRKYRENMKAELLETWDNISWPKDHVYIRNTSKDEHEELQRLLDPNRTRAQAQTIVLVGRAGVGKTTLAMQAMLHWANGVLFQQRFSYVFYLSCHKIRYMKETTFAELISLDWPDFDAPIEEFMSQPEKLLFIIDGFEEIIISESRSESLDDGSPCTDWYQELPVTKILHSLLKKELVPLATLLITIKTWFVRDLKASLVNPCFVQITGFTGDDLRVYFMRHFDDSSEVEKILQQLRKNETLFHSCSAPMVCWTVCSCLKQPKVRYYDLQSITQTTTSLYAYFFSNLFSTAEVDLADDSWPGQWRALCSLAIEGLWSMNFTFNKEDTEIEGLEVPFIDSLYEFNILQKINDCGGCTTFTHLSFQEFFAAMSFVLEEPREFPPHSTKPQEMKMLLQHVLLDKEAYWTPVVLFFFGLLNKNIARELEDTLHCKISPRVMEELLKWGEELGKAESASLQFHILRLFHCLHESQEEDFTKKMLGRIFEVDLNILEDEELQASSFCLKHCKRLNKLRLSVSSHILERDLEILETSKFDSRMHAWNSICSTLVTNENLHELDLSNSKLHASSVKGLCLALKNPRCKVQKLTCKSVTPEWVLQDLIIALQGNSKLTHLNFSSNKLGMTVPLILKALRHSACNLKYLCLEKCNLSAASCQDLALFLTSIQHVTRLCLGFNRLQDDGIKLLCAALTHPKCALERLELWFCQLAAPACKHLSDALLQNRSLTHLNLSKNSLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTREGCGELANALSHNHNVKILDLGENDLQDDGVKLLCEALKPHRALHTLGLAKCNLTTACCQHLFSVLSSSKSLVNLNLLGNELDTDGVKMLCKALKKSTCRLQKLG", "length": 1043 }, "evidence": [ { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W26-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 10", "gene_name": "NLRP10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGRYNQVLLVAKPSSESPESLACPFPEQELESVTVEALFDSGEKPSLAPSLVVLQGSAGTGKTTLARKMVLDWATGTLYPGRFDYVFYVSCKEVVLLLESKLEQLLFWCCGDNQAPVTEILRQPERLLFILDGFDELQRPFEEKLKKRGLSPKESLLHLLIRRHTLPTCSLLITTRPLALRNLEPLLKQARHVHILGFSEEERARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRVLRSLCSLAAEGIQHQRFLFEEAELRKHNLDGPRLAAFLSSNDYQLGLAIKKFYSFRHISFQDFFHAMSYLVKEDQSRLGKESRREVQRLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQSQNLFSVKSSLSHGPKEEQKCPSVHGQKEGKDNIAGTQKEASTGKGRGTEETPKNTYI", "length": 655 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W28-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 8", "gene_name": "NLRP8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDVNPPSDTPIPFSSSSTHSSHIPPWTFSCYPGSPCENGVMLYMRNVSHEELQRFKQLLLTELSTGTMPITWDQVETASWAEVVHLLIERFPGRRAWDVTSNIFAIMNCDKMCVVVRREINAILPTLEPEDLNVGETQVNLEEGESGKIRRYKSNVMEKFFPIWDITTWPGNQRDFFYQGVHRHEEYLPCLLLPKRPQGRQPKTVAIQGAPGIGKTILAKKVMFEWARNKFYAHKRWCAFYFHCQEVNQTTDQSFSELIEQKWPGSQDLVSKIMSKPDQLLLLLDGFEELTSTLIDRLEDLSEDWRQKLPGSVLLSSLLSKTMLPEATLLIMIRFTSWQTCKPLLKCPSLVTLPGFNTMEKIKYFQMYFGHTEEGDQVLSFAMENTILFSMCRVPVVCWMVCSGLKQQMERGNNLTQSCPNATSVFVRYISSLFPTRAENFSRKIHQAQLEGLCHLAADSMWHRKWVLGKEDLEEAKLDQTGVTAFLGMSILRRIAGEEDHYVFTLVTFQEFFAALFYVLCFPQRLKNFHVLSHVNIQRLIASPRGSKSYLSHMGLFLFGFLNEACASAVEQSFQCKVSFGNKRKLLKVIPLLHKCDPPSPGSGVPQLFYCLHEIREEAFVSQALNDYHKVVLRIGNNKEVQVSAFCLKRCQYLHEVELTVTLNFMNVWKLSSSSHPGSEAPESNGLHRWWQDLCSVFATNDKLEVLTMTNSVLGPPFLKALAAALRHPQCKLQKLLLRRVNSTMLNQDLIGVLTGNQHLRYLEIQHVEVESKAVKLLCRVLRSPRCRLQCLRLEDCLATPRIWTDLGNNLQGNGHLKTLILRKNSLENCGAYYLSVAQLERLSIENCNLTQLTCESLASCLRQSKMLTHLSLAENALKDEGAKHIWNALPHLRCPLQRLVLRKCDLTFNCCQDMISALCKNKTLKSLDLSFNSLKDDGVILLCEALKNPDCTLQILELENCLFTSICCQAMASMLRKNQHLRHLDLSKNAIGVYGILTLCEAFSSQKKREEVIFCIPAWTRITSFSPTPHPPDFTGKSDCLSQINP", "length": 1048 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BU40-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4A", "gene_name": "Nlrp4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEVLQLGLKQVSWTEVKKASRQDLASLLLKHYEEKPAWDMTFRFFQKINRKDLIERAKREIDGCPKLYRAHMKTKMTHDSSRAFTISIQNFLKEKFTEDDYDCFENLFQSKGTESKPQVVFLSGGAGVGKTLMLKRLMLAWIESPVFLHKFSYIFYFCCREVKQLKTASLAELISREWPGPSAPIEEILSKPEKLLFIIDSLEGMECDLFKWESELCDNCTEKQPVNVLLSSLLRRKMLPESSLLISATPESFEKMENRIEYTHVKIIKGLKERNIKMSFHRLFQDRNRAHEAFSLVRENEQLFTVCQVPVLCWMVATCLKEEIEKGRDPVSICRCTTSLYTTHIFNLFIPQNAHSPSKKSQDQLQGLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPILLDIGMLINIRESEKSYIFLHPSVQEVCAAIFYLLKSHVDHPSQEVKSIEKLMFAFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQIDGMKLFYCLFEMDDDTFLVEAMNCMEQINFVAKDYSDVIVAAHCLKHCFTLKKLSFSTQNVLSGAQEHSYMERLLTAWNHICSVFIISKDIQELRMKDTNLSESAFSVLYNNLKYHNYTLNVLVANNVFFVCEKYLFFELIQNCNLQHLNLSLTILSHSDVKLLCDVLSQAECNIEELVVAACSISSDDCKVFASVLISNKTLKHLNLASNTLDKGIASLCKSLCHPDCILEHLVLANCSLNEKCWDYLSEVLRRNKTLSHLDISSNDLKDEGLKVLCRALTLPDSVLKSLSLRHCLITISGCQDLAEVLRNNQNLVSLQVSNNKLEDTGVKLLCDAIKHPNCHLEDLGLEACELTGACCEDLASTFTQCKTLWAMNLLKNALDYNGLVVLCEALKQQTCATYVLGLQITDFDTETQAFLVAEQEKNPCLRILSSL", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C6J9-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4B", "gene_name": "Nlrp4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLFSDFGFIWYWKELNKIEFMYFKELLIHEILQMGLKQISWTEVKEASREDLAILLVKHCDGNQAWDTTFRVFQMIGRNVITNRATGEIAAHSTIYRAHLKEKLTHDCSRKFNISIQNFFQDEYDHLENLLVPNGTENNPKMVVLQGVAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCHDVKQLQTASLADLISREWPSPSAPMEEILSQPEKLLFIIDSLEGMEWNVTQQDSQLCYNCMEKQPVNVLLSSLLRKKILPESSLLISTSCETFKDLKDWIEYTNVRTITGFKENNINMCFHSLFQDRNIAQEAFSLIRENEQLFTVCQAPVVCYMVATCLKNEIESGKDPVSICRRTTSLYTTHILNLFIPHNAQNPSNNSEDLLDNLCFLAVEGMWTDISVFNEEALRRNGIMDSDIPTLLDIGILEQSRESENSYIFLHPSVQEFCAAMFYLLHSEMDHSCQGVYFIETFLFTFLNKIKKQWVFLGCFFFGLLHETEQEKLEAFFGYHLSKELRRQLFLWLELLLDTLHPDVKKINTMKFFYCLFEMEEEVFVQSAMNCREQIDVVVKGYSDFIVAAYCLSHGSALTDFSISAQNVLNEELGQRGKLLILWHQICSVFLRNKDIKTLRIEDTIFNEPVFKIFYSYLKNSSCILKTLVAYNVSFLCDKRLFLELIQSYNLEELYLRGTFLSHSDVEMLCDILNQAECNIRILDLANCSLCEHSWDYLSDVLRQNKSLRYLNISYNNLKDEGLKALCRALTLPNSALHSLSLEACQLTGACCKDLASTFTRYKCLRRINLAKNSLGFSGLFVLCKAMKDQTCTLYELKLRMADFDSDSQEFLLSEMERNKILSIENGV", "length": 863 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4B8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWNDTCTSHSSMVCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIGRTKMRDSPMSSLKLELLFEPEDGHSEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSDYLQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFFHNSPKEEEEERRGGRPLDQVQCVFPDTHVACSSRLVNCCLTSSFCRGLFSSLSTNRSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSSSQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTNQNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHNHSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNRETKRALEALQEEKPELTIVFEISW", "length": 1033 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WX94-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 7", "gene_name": "NLRP7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQIARGLWILCQALENPNCNLKHLRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATAPPCCDFFC", "length": 980 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96MN2-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4", "gene_name": "NLRP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQMTLQLELKQIPWTEVKKASREELANLLIKHYEEQQAWNITLRIFQKMDRKDLCMKVMRERTGYTKTYQAHAKQKFSRLWSSKSVTEIHLYFEEEVKQEECDHLDRLFAPKEAGKQPRTVIIQGPQGIGKTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELRELPPTSLADLISREWPDPAAPITEIVSQPERLLFVIDSFEELQGGLNEPDSDLCGDLMEKRPVQVLLSSLLRKKMLPEASLLIAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQLFSICQIPLLCWILCTSLKQEMQKGKDLALTCQSTTSVYSSFVFNLFTPEGAEGPTPQTQHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGERESSYVFLHVCIQEFCAALFYLLKSHLDHPHPAVRCVQELLVANFEKARRAHWIFLGCFLTGLLNKKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFVKQAVNLLQEANFHIIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFKKEDEHSSTSDYSLICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFSGQSVLLFEVLFYQPDLKYLSFTLTKLSRDDIRSLCDALNYPAGNVKELALVNCHLSPIDCEVLAGLLTNNKKLTYLNVSCNQLDTGVPLLCEALCSPDTVLVYLMLAFCHLSEQCCEYISEMLLRNKSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDLASALISNQNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLASVLTCSKTLQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRKTDFDEETQALLTAEEERNPNLTITDDCDTITRVEI", "length": 994 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW", "length": 1036 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9C000-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 1", "gene_name": "NLRP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGLDQTTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS", "length": 1473 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAM1-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Lrrc34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKLQAQYCYLCSENIRKTNPFILNILQKLDEEIEKRPKEKFTVNIAGNNRLDSGQRITGEDFWLLSKTLRNQPCISGVDVRYNLIGDVGAFYAAKLLQKQPSITYLNLMFNDIGPEGGELIAKALHKNKTLKYLRMTGNKIENTGGMLFAAMLQMNSSLEKLDLGDCDLGLQCVIAFSTVLTQNQAIKGINLNRPILYGEQEESTVHIGHMLKENHVLVELHMCKHGMKNYGLQQLCNALYLNSSLRYLDVSCNKITRDGMVFLADVLKSNTTLEVLDLSFNRIETAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMKTNLVLSNIYIWGNKFDEDTCVAYSDLIKSGRLKPDNTDVEPYMVDEHIYLSEVSNGLKRHYYWAPTYGETYMPSSSAGFALVPVGEHL", "length": 415 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NX02-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 2", "gene_name": "NLRP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSSAQMGFNLQALLEQLSQDELSKFKYLITTFSLAHELQKIPHKEVDKADGKQLVEILTTHCDSYWVEMASLQVFEKMHRMDLSERAKDEVREAALKSFNKRKPLSLGITRKERPPLDVDEMLERFKTEAQAFTETKGNVICLGKEVFKGKKPDKDNRCRYILKTKFREMWKSWPGDSKEVQVMAERYKMLIPFSNPRVLPGPFSYTVVLYGPAGLGKTTLAQKLMLDWAEDNLIHKFKYAFYLSCRELSRLGPCSFAELVFRDWPELQDDIPHILAQARKILFVIDGFDELGAAPGALIEDICGDWEKKKPVPVLLGSLLNRVMLPKAALLVTTRPRALRDLRILAEEPIYIRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQTSVLHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYTLEKEEEEDRDGHTWDIGDVQKLLSGVERLRNPDLIQAGYYSFGLANEKRAKELEATFGCRMSPDIKQELLRCDISCKGGHSTVTDLQELLGCLYESQEEELVKEVMAQFKEISLHLNAVDVVPSSFCVKHCRNLQKMSLQVIKENLPENVTASESDAEVERSQDDQHMLPFWTDLCSIFGSNKDLMGLAINDSFLSASLVRILCEQIASDTCHLQRVVFKNISPADAHRNLCLALRGHKTVTYLTLQGNDQDDMFPALCEVLRHPECNLRYLGLVSCSATTQQWADLSLALEVNQSLTCVNLSDNELLDEGAKLLYTTLRHPKCFLQRLSLENCHLTEANCKDLAAVLVVSRELTHLCLAKNPIGNTGVKFLCEGLRYPECKLQTLVLWNCDITSDGCCDLTKLLQEKSSLLCLDLGLNHIGVKGMKFLCEALRKPLCNLRCLWLWGCSIPPFSCEDLCSALSCNQSLVTLDLGQNPLGSSGVKMLFETLTCSSGTLRTLRLKIDDFNDELNKLLEEIEEKNPQLIIDTEKHHPWAERPSSHDFMI", "length": 1062 }, "evidence": [ { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131122-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131122-52#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1F5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1F5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1F5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1F5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1043, "end_pos": 1045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 664, "end_pos": 666, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 695, "end_pos": 697, "annotation": "n_glycosylation_sequon" }, { "start_pos": 753, "end_pos": 755, "annotation": "n_glycosylation_sequon" }, { "start_pos": 804, "end_pos": 806, "annotation": "n_glycosylation_sequon" }, { "start_pos": 942, "end_pos": 944, "annotation": "n_glycosylation_sequon" }, { "start_pos": 954, "end_pos": 956, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z1F5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1F5" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 293, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 47 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1043, "end_pos": 1045 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 664, "end_pos": 666 }, { "start_pos": 688, "end_pos": 690 }, { "start_pos": 695, "end_pos": 697 }, { "start_pos": 753, "end_pos": 755 }, { "start_pos": 804, "end_pos": 806 }, { "start_pos": 942, "end_pos": 944 }, { "start_pos": 954, "end_pos": 956 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z1G3-1", "uniprot_ac": "A0A8M6Z1G3", "uniprot_id": "A0A8M6Z1G3_DANRE", "mass": { "chemical_mass": 62900.0, "monoisotopic_mass": 62900.0 }, "refseq": { "ac": "XP_017212300", "name": "B-cell receptor CD22-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212300" }, "gene_names": [ { "name": "LOC100149247", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1G3" } ] }, { "name": "LOC100149247", "type": "synonym", "evidence": [ { "id": "XP_017212300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212300" } ] } ], "protein_names": [ { "name": "B-cell receptor CD22-like", "type": "synonym", "evidence": [ { "id": "XP_017212300", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212300" }, { "id": "A0A8M6Z1G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1G3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017212300.2. 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"MLMWLRMAPALHLIFLLIIHRVSAADWGVNYSPSQYCALQNSTMTISCTFIYPTTGYQIMKAFWNIDQVKPDGVEFADLSVNPEYSQRLQYLGNKQQNCTVRLSHVTKKDEHDYLFRFTTNVTTGKIIGIPGVVLSVTDLQLESPERVTEGDSVRLTCRSSCKLTDTPTFIWYRNSHTLTNIGDELNISPVNRTEAGHYSCGVQGQTYISPAVYLNVTYPPDTPVISNRSAVIMSGDSVTLNCSSDSNPPAEISWYKANKSLSSGRIFNISKISSDDSGEYKCRARNDHGEKYSDPVTLDVQYPPRNISVSMNRSAVIKEGDSVTLNCSSDSNPPAEINWYKGEMVVRSGRIFNISNISSDDSGEYKCRARNEHGEKNSDPVTLDVQYPPRNVSVFVTDSGQLFSDSVSLMCIIDSNPPALSFSWFKENQSSAVGSGQSFSAVQSGRFYCEAHNPHGAQRSDAVTVTVHQHAERNIIITATSVGVLIIIIVVIIFAIHFKRKSRRSAGKESANSDTYAGLDLQSATSDLYNTLTTVHHRPAENSCSTLDPQSSSEHHNPPINRRRLQ", "length": 567, "header": "tr|A0A8M6Z1G3-1|A0A8M6Z1G3_DANRE Isoform 1 of B-cell receptor CD22-like OS=Danio rerio OX=7955 GN=LOC100149247 PE=4 SV=3 CANONICAL=A0A8M6Z1G3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100149247", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100149247", "resource": "KEGG Pathway" 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"start_pos": 131, "end_pos": 218, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 187, "end_pos": 189 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 307, "end_pos": 309 }, { "start_pos": 30, "end_pos": 32 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z1G9-1", "uniprot_ac": "A0A8M6Z1G9", "uniprot_id": "A0A8M6Z1G9_DANRE", "mass": { "chemical_mass": 30969.0, "monoisotopic_mass": 30969.0 }, "refseq": { "ac": "XP_017206603", "name": "uncharacterized protein si:ch1073-83n3.2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206603" }, "gene_names": [ { "name": "si:ch1073-83n3.2", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1G9" } ] }, { "name": "si:ch1073-83n3.2", "type": "synonym", "evidence": [ { "id": "XP_017206603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206603" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch1073-83n3.2", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1G9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch1073-83n3.2", "type": "synonym", "evidence": [ { "id": "XP_017206603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206603" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017206603", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206603" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1G9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1G9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch1073-83n3.2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1G9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141219-10", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141219-10", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00821", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00821", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100000241", "url": "https://www.ncbi.nlm.nih.gov/gene/100000241", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100000241", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000241", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1G9", "url": "https://www.orthodb.org/?gene=A0A8M6Z1G9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14309", "url": 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eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213596" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1I0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1I0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "taar19a", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1I0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100519-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100519-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z1I0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z1I0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "108191523", "url": "https://www.ncbi.nlm.nih.gov/gene/108191523", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108191523", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191523", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1I0", "url": "https://www.orthodb.org/?gene=A0A8M6Z1I0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249:SF381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249:SF381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213596", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213596", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1I0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100519-3", "url": "https://zfin.org/ZDB-GENE-100519-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKGRHSSHGYIIIYLFVSLLSVWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLIIGLFVIPIQAIKLIETCWYFGDTFCGLYLFLIFELLSASLSNLVLIAVDRYVAVCHPLLYPQKITITKTLMSICLSWVCYSAYNTALIINNRYSETSHRTDECYGRCFIVMSFSWLVADLVMSFIFPCLIMITLYLMIFYVVHQQVKVMNSLMKGGKCVTEGSVKRKSESKAALTLGIIVTIYLLCYIPYYICSLVVNSSTAIHVMSWTVYVNSGMNPLVYALFYPWFKKTAKIIFTLKIFQPASSLINIFTELDM", "length": 335, "header": "tr|A0A8M6Z1I0-1|A0A8M6Z1I0_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=taar19a PE=3 SV=1 CANONICAL=A0A8M6Z1I0-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1I0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1I0/entry#A0A8M6Z1I0-1", "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKGRHSSHGYIIIYLFVSLLSVWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLIIGLFVIPIQAIKLIETCWYFGDTFCGLYLFLIFELLSASLSNLVLIAVDRYVAVCHPLLYPQKITITKTLMSICLSWVCYSAYNTALIINNRYSETSHRTDECYGRCFIVMSFSWLVADLVMSFIFPCLIMITLYLMIFYVVHQQVKVMNSLMKGGKCVTEGSVKRKSESKAALTLGIIVTIYLLCYIPYYICSLVVNSSTAIHVMSWTVYVNSGMNPLVYALFYPWFKKTAKIIFTLKIFQPASSLINIFTELDM", "length": 335, "header": "tr|A0A8M6Z1I0-1|A0A8M6Z1I0_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=taar19a PE=3 SV=1 CANONICAL=A0A8M6Z1I0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108191523", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191523", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NV51-1", "protein_name": "Trace amine associated receptor 19p", "gene_name": "taar19p", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEHQDTQYCFPNINSSCVKGKRSIQEYNIMYVLFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVTDLLIGLIVMPIQAIRLIETCWYFGDTLCGINLIIIGVIFSASFSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMCICLSWVYYSAYNTGLVINNGYFDTSHRTDVCYGDCSVIMSFSWLVTDLCLSFIFPCVIMITLYLRIFYVVHQQVKVINSLMKGGKCVTKGSVKRKSESKAALTLGIIVLVYLLCYIPYYICTLSVNSSTTITVLEWTVYTNSGLNPLVYALFYHWFKKTVKLILTLKIFHPESSLINVFTVHEL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z0V5-1", "protein_name": "Trace amine-associated receptor 13c", "gene_name": "taar19t", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDADTVYIKGQKGEQNKLLTGGDSLMAYETEDQETQYCFPDINSSCVKEKRSIQEYNIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLILMPVEAIRLIETCWYFGETFCVLYLILIGLIFSATLSCLVLIAVDRYVAVCHPLLYPQKITITNMLMSICLSWVCYSAYNTAFAFNNGYLNSSHRRDVCYGQCFIMMTFSWTVTDLSMCFIFPCVIMITLYSRIFYVVHQQVKVINSLMKGGKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTITVLMWTVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 361 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z0W1-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19h", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDYETEDQETQYCFPDINSSCVKYQRSSHEYNIMYVFFYFLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLVGLIVMPIQAIRLIETCWYFGDTFCGISLILSGVIISASLTNLVLIAVDRYVAVCHPLLYPQKITITNMLLIICLSWIYYSGYNTVLIIYNGYFETSERTDACDGDCLVMIRFSWIVTDLFISFIFPCVIIITLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVKRKSESKAALTLGIIVSVYLLSWIPYCICSVTVNSSTLITILSWTVYTNSGLNPLVYAIFYPWFKKTVKVILTLKIFDPASSLVNIFMEHDL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z335-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19r", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEHQETQYCFPNINSSCVKGRRYRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILFLAVNDLLIGLIVLPVEAIRLIERCWYFGETFCFLYLILIVLIFSASLSYLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNIAFVINNRNLNSSQKTDVCYGQCLIMMSFSWTIIDLSICFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGAKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTINVLMWNVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z339-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "si:ch211-139n6.11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKGKRSRHEYIIMYVFFLLLSAWTVILNLLVIISISHFKKLHSPTNLLILSLSVADLLVGLIVIPIEAIKQIETCWYFGATFCGINLIIIGVIFSASFSNLVLIAVDRYVAVCHPLLYPQKITTAKMLMSICLSWLYYSAYNAGLVVNNGYFDTAHRTDVCYGDCTVIMSFGWIVIDLFMSFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKCLTEISVKRKSESKAALTLGIIVLVYLFSYIPYYICTLSVNSVTTNNVLGWTVYANSGLNPLVYALFYPWFKKTAKIILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z8I1-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19s", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKGRRYRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILFLAVNDLLIGLIVLPVEAIRLIERCWYFGETFCFLYLILIVLIFSASLSYLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNIAFVINNRNLNSSQKTDVCYGQCLIMMSFSWTVIDLSICFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTINVLMWNVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z8X3-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "si:ch211-238p8.31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKEKRSSHEYNIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVTDMFVGLIVIPVKAIKLIERCWYFGDTFCGLFIIIIGVIFSASLSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMSICLSWLYYSAYNTALIINNGYFDTSNRTDMCNGECPVMVSFSWILTDLSMCFIFPCLIMITLYSRIFFAVHQQVKVINSLMKRDKCVMKGSVKRKSERKAALTLGIIVTIYLLCYIPYYICSLVIISSTALNVLTWTMYANSGLNPLVYALFYPWFKKTAKLILTLKIFQPASSLVNIFTENEL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCQ8-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKEQHSTNGYIIYLFVSFLSAWTVFLNLLVIISISHFKKLHTPTNMIVLSLAVADLLIGLIVMPVEAVKLIETCWYFGDTFCGFTLILIGVIPSASLGNLVLIAVDRYAAVCHPLLYPQKITMANMLMSICLSWVYYSTYITTLVIYNRYFDTSHRTDECYGQCLVMMSFSWILTDLFVCFVFPCVLIITLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVKRKSESKAALTLGIIVSVYLLCWIPYYICTLTVNSSTVLSVLTWVLYANSGLNPLVYALFYPWFKKTVKHILTMTICQLASSLVNIFTEHEL", "length": 334 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QD04-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "Taar9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSDFSPEPPMELCYENVNGSCIKSSYAPWPRAILYGVLGLGALLAVFGNLLVIIAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVESCWYFGESYCKFHTCFDTSFCFASLFHLCCISIDRYIAVTDPLTYPTKFTVSVSGLCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKYQARKIEGTANQAQASSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSTTNLFSEEAGAG", "length": 348 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100519-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100519-3#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5QD16-1", "protein_name": "Trace amine-associated receptor 3", "gene_name": "Taar3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLIYIPEDLSSCPKFGNKSCPPTNRSFRVRMIMYLFMTGAMVITIFGNLVIIISISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSMVRSVESCWYFGDSFCKFHASFDMMLSLTSIFHLCSIAIDRFYAVCDPLHYTTTMTVSMIKRLLAFCWAAPALFSFGLVLSEANVSGMQSYEILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSRRHARALSDMPANTKGAVGKNLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPIIVLDLLVWLGYFNSTCNPLIHGFFYPWFRKALQFIVSGKIFRSNSDTANLFPEAH", "length": 343 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5QD24-1", "protein_name": "Trace amine-associated receptor 3", "gene_name": "Taar3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLIYIPEDLSSCPKFGNKSCPPTNRSFRVRLIMYLLMTGAMVITIFGNLVIIISISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSMVRSVESCWYFGDSFCKFHASFDMMLSLTSIFHLCSIAIDRFYAVCAPLHYTTTMTASMIKRLLFFCWAAPALFSFGLVLSEANVSGMQSYEILIACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSRRHARALGNMPENTKGAGRNLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPIIVLDLLVWLGYFNSTCNPLIHGFFYPWFRKALEHIVSGKIFRSNSDTANLFPEAH", "length": 342 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100519-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100519-3#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q923Y6-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "Taar9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELCYENVNGSCIKSSYSPWPRAILYAVLGLGALLAVFGNLLVITAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVEGCWYFGDTYCKFHTCFDTSFCFASLFHLCCISIDRYVAVTDPLTYPTKFTISVSGVCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKQQARKIEGSANQPQASSESYKERVARRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSRTNLFSEEAGAG", "length": 338 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96RI9-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "TAAR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD", "length": 348 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100519-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100519-3#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9P1P4-1", "protein_name": "Putative trace amine-associated receptor 3", "gene_name": "TAAR3P", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLTYIPEDLSSCPKFVNKILSSHQPLFSCPGDNVFGYDWSHDYPLFGNLVIMVSISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSIMRSVESCWYFGDGFCKFHTSFDMMLRLTSIFHLCSIAIDRFYAVCYPLHYTTKMTNSTIKQLLAFCWSVPALFSFGLVLSEADVSGMQSYKILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSKQHARVISHVPENTKGAVKKHLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPILILDLLVWLRYFNSTCNPLIHGFFNPWFQKAFKYIVSGKIFSSHSETANLFPEAH", "length": 343 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1I0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1I0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1I0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1I0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "trace-amine receptor activity", "id": "GO:0001594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001594", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1I0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1I0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z1I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1I0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 300, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 277, "end_pos": 279 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z1K9-1", "uniprot_ac": "A0A8M6Z1K9", "uniprot_id": "A0A8M6Z1K9_DANRE", "mass": { "chemical_mass": 65987.0, "monoisotopic_mass": 65987.0 }, "refseq": { "ac": "XP_017207208", "name": "kelch-like protein 10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207208" }, "gene_names": [ { "name": "klhl10a", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9" } ] }, { "name": "klhl10a", "type": "synonym", "evidence": [ { "id": "XP_017207208", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207208" } ] } ], "protein_names": [ { "name": "Kelch-like protein 10 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017207208", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207208" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017207208.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017207208", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207208" } ] } ], "disease": [ { "disease_id": "DOID:0070180", "recommended_name": { "id": "DOID:0070180", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070180", "name": "spermatogenic failure 11", "description": "A spermatogenic failure that is characterized by autosomal dominant inheritance of oligozoospermia and in some cases teratozoospermia and/or moderate asthenozoospermia that has_material_basis_in mutation in the KLHL10 gene on chromosome 17q21." }, "synonyms": [ { "id": "DOID:0070180", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070180", "name": "SPGF11", "description": "" }, { "id": "MONDO:0014037", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014037", "name": "spermatogenic failure 11", "description": "Any azoospermia in which the cause of the disease is a mutation in the KLHL10 gene." }, { "id": "MONDO:0014037", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014037", "name": "KLHL10 azoospermia", "description": "" }, { "id": "MONDO:0014037", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014037", "name": "azoospermia caused by mutation in KLHL10", "description": "" }, { "id": "MONDO:0014037", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014037", "name": "spermatogenic failure 11", "description": "" }, { "id": "MONDO:0014037", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014037", "name": "spermatogenic failure type 11", "description": "" }, { "id": "MONDO:0014037", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014037", "name": "SPGF11", "description": "" }, { "id": "MIM:615081", "resource": "MIM", "url": "https://www.omim.org/entry/615081", "name": "Spermatogenic failure 11", "description": "Spermatogenic failure 11" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070180", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070180" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1K9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "klhl10a", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131015-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131015-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z1K9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z1K9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100333629", "url": "https://www.ncbi.nlm.nih.gov/gene/100333629", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100333629", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333629", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1K9", "url": "https://www.orthodb.org/?gene=A0A8M6Z1K9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF172", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF172", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017207208", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207208", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1K9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQE1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQE1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQE3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQE3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQE3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131015-1", "url": "https://zfin.org/ZDB-GENE-131015-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMDPAFEVFNEVRLQGEHTDVDINVHGKVFRVHKIILCGCSPYFRMLFSTQWTKPKQHFNFPEMSSDTMSLIIQHAYARPVQITEDNVCELLVAADQLLISGLTEACCKFLEANFSLQNCIGIWAFTERFHSCTELHHKAEFYVLQHFQEVQQVSEEFLQLPLELLENMISRDELNVKQEEVVFEAILRWINHEPENRRNHITALLSRVRLGLMSPEYFMNNVRNNPLVLENEACSFIIINAMKVIFDLHVEPTSSGLVSYMTRQRMPSEVLLAIGGWSIGNPTNGIEAYDTRANCWKDVTVENELPRAYHGVAVLDGFIYAVGGFDSENYFSSVRKFNPVTHTWHEVAPMYERRCYVSVAVLDGLLYAIGGFNGHARLKTAECYNKNTNQWTQISPMSERRSDASATSLHGKVYICGGFTGVECLFTAESFNPETNQWSLIEPMRTRRSGVGVITFGNLIYAVGGFDGSSRLRSVEAYDPHTDSWHDIESMINTRSNFGIEVVNDQLIVVGGFNGFRTCSDVEIYNQSTNEWVEVCDMNISRSALSCCVISGLPQCLQYVFDRDSLPMLEEESDESNQE", "length": 580, "header": "tr|A0A8M6Z1K9-1|A0A8M6Z1K9_DANRE Isoform 1 of Kelch-like protein 10 isoform X1 OS=Danio rerio OX=7955 GN=klhl10a PE=1 SV=2 CANONICAL=A0A8M6Z1K9-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9/entry#A0A8M6Z1K9-1", "sequence": { "sequence": "MMDPAFEVFNEVRLQGEHTDVDINVHGKVFRVHKIILCGCSPYFRMLFSTQWTKPKQHFNFPEMSSDTMSLIIQHAYARPVQITEDNVCELLVAADQLLISGLTEACCKFLEANFSLQNCIGIWAFTERFHSCTELHHKAEFYVLQHFQEVQQVSEEFLQLPLELLENMISRDELNVKQEEVVFEAILRWINHEPENRRNHITALLSRVRLGLMSPEYFMNNVRNNPLVLENEACSFIIINAMKVIFDLHVEPTSSGLVSYMTRQRMPSEVLLAIGGWSIGNPTNGIEAYDTRANCWKDVTVENELPRAYHGVAVLDGFIYAVGGFDSENYFSSVRKFNPVTHTWHEVAPMYERRCYVSVAVLDGLLYAIGGFNGHARLKTAECYNKNTNQWTQISPMSERRSDASATSLHGKVYICGGFTGVECLFTAESFNPETNQWSLIEPMRTRRSGVGVITFGNLIYAVGGFDGSSRLRSVEAYDPHTDSWHDIESMINTRSNFGIEVVNDQLIVVGGFNGFRTCSDVEIYNQSTNEWVEVCDMNISRSALSCCVISGLPQCLQYVFDRDSLPMLEEESDESNQE", "length": 580, "header": "tr|A0A8M6Z1K9-1|A0A8M6Z1K9_DANRE Isoform 1 of Kelch-like protein 10 isoform X1 OS=Danio rerio OX=7955 GN=klhl10a PE=1 SV=2 CANONICAL=A0A8M6Z1K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9/entry#A0AC58HQE1-1", "sequence": { "sequence": "MKLSIFIKQHCLNVLHRMLFSTQWTKPKQHFNFPEMSSDTMSLIIQHAYARPVQITEDNVCELLVAADQLLISGLTEACCKFLEANFSLQNCIGIWAFTERFHSCTELHHKAEFYVLQHFQEVQQVSEEFLQLPLELLENMISRDELNVKQEEVVFEAILRWINHEPENRRNHITALLSRVRLGLMSPEYFMNNVRNNPLVLENEACSFIIINAMKVIFDLHVEPTSSGLVSYMTRQRMPSEVLLAIGGWSIGNPTNGIEAYDTRANCWKDVTVENELPRAYHGVAVLDGFIYAVGGFDSENYFSSVRKFNPVTHTWHEVAPMYERRCYVSVAVLDGLLYAIGGFNGHARLKTAECYNKNTNQWTQISPMSERRSDASATSLHGKVYICGGFTGVECLFTAESFNPETNQWSLIEPMRTRRSGVGVITFGNLIYAVGGFDGSSRLRSVEAYDPHTDSWHDIESMINTRSNFGIEVVNDQLIVVGGFNGFRTCSDVEIYNQSTNEWVEVCDMNISRSALSCCVISGLPQCLQYVFDRDSLPMLEEESDESNQE", "length": 552, "header": "tr|A0AC58HQE1-1|A0AC58HQE1_DANRE Computationally mapped isoform of Kelch-like protein 10 isoform X2 OS=Danio rerio OX=7955 GN=klhl10a PE=4 SV=1 CANONICAL=A0A8M6Z1K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9/entry#A0AC58HQE3-1", "sequence": { "sequence": "MLFSTQWTKPKQHFNFPEMSSDTMSLIIQHAYARPVQITEDNVCELLVAADQLLISGLTEACCKFLEANFSLQNCIGIWAFTERFHSCTELHHKAEFYVLQHFQEVQQVSEEFLQLPLELLENMISRDELNVKQEEVVFEAILRWINHEPENRRNHITALLSRVRLGLMSPEYFMNNVRNNPLVLENEACSFIIINAMKVIFDLHVEPTSSGLVSYMTRQRMPSEVLLAIGGWSIGNPTNGIEAYDTRANCWKDVTVENELPRAYHGVAVLDGFIYAVGGFDSENYFSSVRKFNPVTHTWHEVAPMYERRCYVSVAVLDGLLYAIGGFNGHARLKTAECYNKNTNQWTQISPMSERRSDASATSLHGKVYICGGFTGVECLFTAESFNPETNQWSLIEPMRTRRSGVGVITFGNLIYAVGGFDGSSRLRSVEAYDPHTDSWHDIESMINTRSNFGIEVVNDQLIVVGGFNGFRTCSDVEIYNQSTNEWVEVCDMNISRSALSCCVISGLPQCLQYVFDRDSLPMLEEESDESNQE", "length": 535, "header": "tr|A0AC58HQE3-1|A0AC58HQE3_DANRE Computationally mapped isoform of Kelch-like protein 10 isoform X3 OS=Danio rerio OX=7955 GN=klhl10a PE=4 SV=1 CANONICAL=A0A8M6Z1K9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100333629", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333629", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9PEI5-1", "protein_name": "Kelch-like protein 10", "gene_name": "klhl10b.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNSPTASNVFDEARLLGEHTDLIIRANGTKFQVHKIIMCACSPYFRVLFSSKWTSTAEHTYDIPEMSPDILYLIIQYAYTRSALITAENVLKLLVTADQLLISGLVAACCQFLDTHLGPENCIGIHMITKDFHSCSKLHHKAKRFILQHFENVLQVSEEFLELPLEELEEIIDDDKLNVRHEEVVFEAILHWIDHEPESRRKHIATLLPKVRLGLMTLQYFMDNVKHNPLVMENEACKPIILSAMKALFDFQFDGPISSELLHRLTRPRLPSAILLAIGGWSNGPTNEIEAFDMRAEQWVNVNKVDERSTAYLGTAVLEEFVYCIGGYDSVEYFNNVRKFNLITQTWHEVAPMYERRCYVSVAVLDGLIYAIGGFDGLERLNSAECYNPDTNQWTLTAQMNERRSDASASSLQGKVYICGGFTGTECLFSAECFNPQTNQWTLIAPMRSRRSGLGVIAYDGLVYAVGGFDGASRLRTAEAYNPLTNMWRDVASMHKTRSNFGIEVVDDQLFAVGGFDGSGTISDVDCYDVEMDEWYSVNKASISRSALSCCVATGLPNIIQYVAQRDAVQIQDESDNE", "length": 581 }, "evidence": [ { "id": "RGD:1303290", "url": "https://alliancegenome.org/gene/RGD:1303290#orthology", "database": "AGR" }, { "id": "HGNC:18829", "url": "https://alliancegenome.org/gene/HGNC:18829#orthology", "database": "AGR" }, { "id": "MGI:2181067", "url": "https://alliancegenome.org/gene/MGI:2181067#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6JEL2-1", "protein_name": "Kelch-like protein 10", "gene_name": "KLHL10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEMESAAASTRFHQPHMERKMSAMACEIFNELRLEGKLCDVVIKVNGFEFSAHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAILKWISHDPQNRKQHISILLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINALKAMYDLNMNGPSNSDFTNPLTRPRLPYAILFAIGGWSGGSPTNAIEAYDARADRWVNVTCEEESPRAYHGAAYLKGYVYIIGGFDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLGNFIYAMGGFDGYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGGFNGNECLFTAEVYNTESNQWTVIAPMRSRRSGIGVIAYGEHVYAVGGFDGANRLRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFTTTFNVECYDEKTDEWYDAHDMSIYRSALSCCVVPGLANVEEYAARRDNFPGLALRDEVKYSASTSTLPV", "length": 608 }, "evidence": [ { "id": "RGD:1303290", "url": "https://alliancegenome.org/gene/RGD:1303290#orthology", "database": "AGR" }, { "id": "HGNC:18829", "url": "https://alliancegenome.org/gene/HGNC:18829#orthology", "database": "AGR" }, { "id": "MGI:2181067", "url": "https://alliancegenome.org/gene/MGI:2181067#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131015-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131015-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6JEL3-1", "protein_name": "Kelch-like protein 10", "gene_name": "Klhl10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEMESSAASTRFHQPHMERKMSAMTCEIFNELRLEGKLCDVVIKVNGFEFNAHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAILKWISHDPQNRKQHISVLLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINALKAMYDLNMNGPSNSDFTNPLTRPRLPYAILFAIGGWSGGSPTNAIEAYDARADRWVNVTCEEESPRAYHGAAYLKGYVYIIGGFDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLSNFIYAMGGFDGYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGGFNGNECLFTAEVYNTESNQWTVIAPMRSRRSGIGVIAYGEHVYAVGGFDGANRLRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFTTTFNVECYDEKTDEWYDAHDMSIYRSALSCCVVPGLANVGEYAARRDNFTGLALRDEVKYSASTSTLPV", "length": 608 }, "evidence": [ { "id": "RGD:1303290", "url": "https://alliancegenome.org/gene/RGD:1303290#orthology", "database": "AGR" }, { "id": "HGNC:18829", "url": "https://alliancegenome.org/gene/HGNC:18829#orthology", "database": "AGR" }, { "id": "MGI:2181067", "url": "https://alliancegenome.org/gene/MGI:2181067#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131015-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131015-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D5V2-1", "protein_name": "Kelch-like protein 10", "gene_name": "Klhl10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMESTAASTRFHQPHMERKMSAMTCEIFNELRLEGKLCDVVIKVNGFEFNAHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAILKWISHDPQNRKQHISVLLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINALKAMYDLNMNGPSNSDFTNPLTRPRLPYAILFAIGGWSGGSPTNAIEAYDARADRWVNVTCEEESPRAYHGAAYLKGYVYIIGGFDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLSNFIYAMGGFDGYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGGFNGNECLFTAEVYNTESNQWTVIAPMRSRRSGIGVIAYGEHVYAVGGFDGANRLRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFTTTFNVECYDEKTDEWYDAHDMSIYRSALSCCVVPGLANVGEYAARRDNFTGLALRDEVKYSASTSTLPV", "length": 608 }, "evidence": [ { "id": "RGD:1303290", "url": "https://alliancegenome.org/gene/RGD:1303290#orthology", "database": "AGR" }, { "id": "HGNC:18829", "url": "https://alliancegenome.org/gene/HGNC:18829#orthology", "database": "AGR" }, { "id": "MGI:2181067", "url": "https://alliancegenome.org/gene/MGI:2181067#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131015-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131015-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1K9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1K9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1K9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1K9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z1K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1K9" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 19, "end_pos": 85, "start_aa": "Thr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 527, "end_pos": 529 }, { "start_pos": 540, "end_pos": 542 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z1M5-1", "uniprot_ac": "A0A8M6Z1M5", "uniprot_id": "A0A8M6Z1M5_DANRE", "mass": { "chemical_mass": 44030.0, "monoisotopic_mass": 44030.0 }, "refseq": {}, "gene_names": [ { "name": "LOC100150236", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M5" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1M5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M5/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1M5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100150236", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M5", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z1M5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z1M5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100150236", "url": "https://www.ncbi.nlm.nih.gov/gene/100150236", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100150236", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100150236", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1M5", "url": "https://www.orthodb.org/?gene=A0A8M6Z1M5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31751:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31751:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_005163468", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163468", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1M5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLHIFKYDSFRCHARLCIEPAIVHKWRNWQSEMLEQLSRRENVIVGGDKRADSPGHSAKYGSYTMMDLATNTVVDLKLVQSNEVGGSYHMEKEGLKRSLDLLDARGVRLECIITDRHPQIQKYLRDRNVTQFFDVWHIEKGISKKLDKICQIKGCEKLRKWLRSIKNHIYWTAASSTTGPERVAKWTSILNHVHEDPNFPAYLHPQRISRDKNKWLSAATMPFYKLEKVLANKRILKDVAKLSPHHQTSTVEAFHSVLLRFAPKNVVFPFLGMLCRLYLAALHYNENAGRPQATSATGKPIYKLAFPKAKKGEYRVRKVKTQQTFGYVKELLDLIFNQVFVDPSPYVDEVLGIHIPPALSSACDLPEMEEAISSRVTRFNQ", "length": 382, "header": "tr|A0A8M6Z1M5-1|A0A8M6Z1M5_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100150236 PE=4 SV=1 CANONICAL=A0A8M6Z1M5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M5/entry#A0A8M6Z1M5-1", "sequence": { "sequence": "MKLHIFKYDSFRCHARLCIEPAIVHKWRNWQSEMLEQLSRRENVIVGGDKRADSPGHSAKYGSYTMMDLATNTVVDLKLVQSNEVGGSYHMEKEGLKRSLDLLDARGVRLECIITDRHPQIQKYLRDRNVTQFFDVWHIEKGISKKLDKICQIKGCEKLRKWLRSIKNHIYWTAASSTTGPERVAKWTSILNHVHEDPNFPAYLHPQRISRDKNKWLSAATMPFYKLEKVLANKRILKDVAKLSPHHQTSTVEAFHSVLLRFAPKNVVFPFLGMLCRLYLAALHYNENAGRPQATSATGKPIYKLAFPKAKKGEYRVRKVKTQQTFGYVKELLDLIFNQVFVDPSPYVDEVLGIHIPPALSSACDLPEMEEAISSRVTRFNQ", "length": 382, "header": "tr|A0A8M6Z1M5-1|A0A8M6Z1M5_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100150236 PE=4 SV=1 CANONICAL=A0A8M6Z1M5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100150236", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100150236", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z1M8-1", "uniprot_ac": "A0A8M6Z1M8", "uniprot_id": "A0A8M6Z1M8_DANRE", "mass": { "chemical_mass": 98336.0, "monoisotopic_mass": 98336.0 }, "refseq": { "ac": "XP_017206723", "name": "short transient receptor potential channel 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206723" }, "gene_names": [ { "name": "trpc2a", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M8" } ] }, { "name": "trpc2a", "type": "synonym", "evidence": [ { "id": "XP_017206723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206723" } ] } ], "protein_names": [ { "name": "Short transient receptor potential channel 2", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M8/entry#names_and_taxonomy" } ] }, { "name": "short transient receptor potential channel 2", "type": "synonym", "evidence": [ { "id": "XP_017206723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206723" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017206723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206723" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "trpc2a", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-602", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z1M8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z1M8", "database": "AlphaFoldDB", "categories": [] }, { "id": "559914", "url": "https://www.ncbi.nlm.nih.gov/gene/559914", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056336", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056336", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:559914", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559914", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1M8", "url": "https://www.orthodb.org/?gene=A0A8M6Z1M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10117:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10117:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23317", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23317", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017206723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206723", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-602", "url": "https://zfin.org/ZDB-GENE-130530-602", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MENLTSDNWREIVNKKLHFPPELILAIQEGNMAWVDSLLSLGDGIIRQLDESEDRLWREALNLSIRLGSEDIMTSLLLGVKFDFRQIHEALLVAVDTNQPRFVKHLLDRLDLEKGNKMDVRSFSMAIFDHSIDDSQFAPGVTPLTLACQKDLYEIVMMLTQRGHDIPLPHAISCTCLECNNGRQYDLLKFSLSRINTYRGIASRAYLSITSEDAMLSAFHLSKELRKLSKKEPEFKPQYLALEELCQEFAVELLGMCRNQSEVSTILNSAEGDSEDEELDEQTFEEGIPNLARLRLAVNYNQKQFVTHPICQQVLSSIWCGSLSGWRGSRTTWKLLVSLGIFLTMPVLCLIYWIAPKSKLGKLLKVPVIKFLLHSASYMWFLIALLTESIFMEIYRTEFASRNQNILHNSLHMVWVAGFFWFECKEVWIEGLKSYFLDLWNILDMMVLSMYLASFTLRILIMLKGYFLCQDSSTQELCDYFTNTVRENWRQEDPQLIAETLFAVTSMLSFTRLAYILPAHESLGTLQISMGRMIDDMMRFMFILMIIGTAFLCGINNIYVPYVISPHLGRLNETFNFLFWTMFGMANQGYVDMPDYALAEFVGRIFYGIFTLLIVIVLLNMLIAMISNSFQRIEDDADVEWKFARSKLYLSYFREGLTMPVPFNIIPSPKAFFYILRGIFQKICCCCQKKAPEYPPITSVSSNAMNSGGGQGEGRVPYRLQVTKALVHRYIEAARREFEESTRKDVGNRITELNKVVGRLHTEMKDFQQKLKWQNKGEPDQANILGKYIKGAKNNFRDFDKNEAMGCENVGLRFSTHPEEEKSKADEDVLMEEEEPESPVEIHPGEQSTAQTADE", "length": 855, "header": "tr|A0A8M6Z1M8-1|A0A8M6Z1M8_DANRE Isoform 1 of Short transient receptor potential channel 2 OS=Danio rerio OX=7955 GN=trpc2a PE=4 SV=1 CANONICAL=A0A8M6Z1M8-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M8/entry#A0A8M6Z1M8-1", "sequence": { "sequence": "MENLTSDNWREIVNKKLHFPPELILAIQEGNMAWVDSLLSLGDGIIRQLDESEDRLWREALNLSIRLGSEDIMTSLLLGVKFDFRQIHEALLVAVDTNQPRFVKHLLDRLDLEKGNKMDVRSFSMAIFDHSIDDSQFAPGVTPLTLACQKDLYEIVMMLTQRGHDIPLPHAISCTCLECNNGRQYDLLKFSLSRINTYRGIASRAYLSITSEDAMLSAFHLSKELRKLSKKEPEFKPQYLALEELCQEFAVELLGMCRNQSEVSTILNSAEGDSEDEELDEQTFEEGIPNLARLRLAVNYNQKQFVTHPICQQVLSSIWCGSLSGWRGSRTTWKLLVSLGIFLTMPVLCLIYWIAPKSKLGKLLKVPVIKFLLHSASYMWFLIALLTESIFMEIYRTEFASRNQNILHNSLHMVWVAGFFWFECKEVWIEGLKSYFLDLWNILDMMVLSMYLASFTLRILIMLKGYFLCQDSSTQELCDYFTNTVRENWRQEDPQLIAETLFAVTSMLSFTRLAYILPAHESLGTLQISMGRMIDDMMRFMFILMIIGTAFLCGINNIYVPYVISPHLGRLNETFNFLFWTMFGMANQGYVDMPDYALAEFVGRIFYGIFTLLIVIVLLNMLIAMISNSFQRIEDDADVEWKFARSKLYLSYFREGLTMPVPFNIIPSPKAFFYILRGIFQKICCCCQKKAPEYPPITSVSSNAMNSGGGQGEGRVPYRLQVTKALVHRYIEAARREFEESTRKDVGNRITELNKVVGRLHTEMKDFQQKLKWQNKGEPDQANILGKYIKGAKNNFRDFDKNEAMGCENVGLRFSTHPEEEKSKADEDVLMEEEEPESPVEIHPGEQSTAQTADE", "length": 855, "header": "tr|A0A8M6Z1M8-1|A0A8M6Z1M8_DANRE Isoform 1 of Short transient receptor potential channel 2 OS=Danio rerio OX=7955 GN=trpc2a PE=4 SV=1 CANONICAL=A0A8M6Z1M8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:559914", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559914", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q12324-1", "protein_name": "Calcium channel YVC1", "gene_name": "YVC1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVSANGDLHLPISNEQCMPENNGSLGFEAPTPRQILRVTLNLKYLIDKVVPIVYDPNDIVCDHSEILSPKVVKLAYEACGGNPKDKANKRKYQSVIIFSLLKVCEWYSILATMEVHNAKLYETRNLASQQLCKLLIEREETRDLQFLFMQLLLRRYVINENDEDQEPLNALELATDMHCTTVIGSSGFQRCLKWIWRGWIVQNGLDPTTFIKDDSLAEVSLISHFNPVRLKAPVYQNYLQMIFSFLFLGLYTLVVNGKDSERVQSFDLLESIFYVFNTGFILDELTKLYYIGYAHLSFWNLFNDTTYLIITFAMGFRAMSVTPLNAKYSSEDWDKISYRVLSCAAPFVWSRLLLYLESQRFIGIMLVILKHMMKESIVFFFLLFLIMIGFTQGFLGLDSADGKRDITGPILGNLTITVLGLGSFDVFEEFAPPYAAILYYGYYFIVSVILLNILIALYSTAYQKVIDNADDEYMALMSQKTLRYIRAPDEDVYVSPLNLIEVFMTPIFRILPPKRAKDLSYTVMTIVYSPFLLLISVKETREARRIKYNRMKRLNDDANEYDTPWDLTDGYLDDDDGLFSDNRNSGMRATQLKNSRSLKLQRTAEQEDVHFKVPKKWYKNVKKCSPSFEQYDNDDTEDDAGEDKDEVKELTKKVENLTAVITDLLEKLDIKDKKE", "length": 675 }, "evidence": [ { "id": "RGD:7692537", "url": "https://alliancegenome.org/gene/RGD:7692537#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6ZNB5-1", "protein_name": "Protein XNDC1N", "gene_name": "XNDC1N", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPVKISHVVSFSSQDPKYPVENLLNPDSPRRPWLGCPQDKSGQLKVELQLERAVPTGYIDVGNCGCAFLQIDVGHSSWPLDRPFITLLPATTLMSLTDSKQGKNRSGVRMFKDVDFLAPASGELWDRLRLTCSRPFTRHQSFGLAFLRVCSSLDSLDDSVVGPSALLSSVLNKIREFKTCFFSWSLKKMELEFSPLLLSINLNDLQFAADAEVSTVSNCMFISIALQSAMIIF", "length": 234 }, "evidence": [ { "id": "RGD:7692537", "url": "https://alliancegenome.org/gene/RGD:7692537#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R244-1", "protein_name": "Short transient receptor potential channel 2", "gene_name": "Trpc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLMSRTDSKSGKNRSGVRMFKDGDFLTPASGESWDRLRLTCSQPFTRHQSFGLAFLRVRSSLGSLADPVVDPSAPGSSGLNQNSTDVLESDPRPWLTNPSIRRTFFPDPQTSTKEISELKGMLKQLQPGPLGRAARMVLSAARKAPPASVVSPNNSHGEPGPSRAESAEPRAEEPNRKTAVGRRKRRKVQEPRRSLSNSSSQPNRRTGRTRQRQHRPQTKSDDGGVQAAGQCPICAGFFSIETLPQHAATCGESPPPQPASPASLSSSESVLRRHHVALTPVPLVPKPQPNWTEIVNKKLKFPPTLLRAIQEGQLGLVQQLLESSSDASGAGPGGPLRNVEESEDRSWREALNLAIRLGHEVITDVLLANVKFDFRQIHEALLVAVDTNQPAVVRRLLARLEREKGRKVDTKSFSLAFFDSSIDGSRFAPGVTPLTLACQKDLYEIAQLLMDQGHTIARPHPVSCACLECSNARRYDLLKFSLSRINTYRGIASRAHLSLASEDAMLAAFQLSRELRRLARKEPEFKPQYIALESLCQDYGFELLGMCRNQSEVTAVLNDLGEDSETEPEAEGLGQAFEEGIPNLARLRLAVNYNQKQFVAHPICQQVLSSIWCGNLAGWRGSTTIWKLFVAFLIFLTMPFLCIGYWLAPKSQLGRLLKIPVLKFLLHSASYLWFLIFLLGESLVMETQLSTFKGRSQSVWETSLHMIWVTGFLWFECKEVWIEGLRSYLLDWWNFLDVVILSLYLASFALRLLLAGLAYMHCRDASDSTTCRYFTTAERSEWRTEDPQFLAEVLFAVTSMLSFTRLAYILPAHESLGTLQISIGKMIDDMIRFMFILMIILTAFLCGLNNIYVPYQESEKLGNFNETFQFLFWTMFGMEEHTVVDMPQFLVPEFVGRAMYGIFTIVMVIVLLNMLIAMITNSFQKIEDDADVEWKFARSKLYLSYFREGLTLPVPFNILPSPKAAFYLVRRIFRFLCCGSSCCKAKKSDYPPIGTFTNPGARAGSAGEGERVSYRLRVIKALVQRYIETARREFEETRRKDLGNRLTELTKTVSRLQSEVASVQKNLAAGGAPRPPDGASILSRYITRVRNSFQNLGPPTSDTPAELTMPGIVETEVSLGDGLDGTGEAGAPAPGEPGSSSSAHVLVHREQEAEGSGDLLLEGDLETKGES", "length": 1172 }, "evidence": [ { "id": "RGD:7692537", "url": "https://alliancegenome.org/gene/RGD:7692537#orthology", "database": "AGR" }, { "id": "MGI:109527", "url": "https://alliancegenome.org/gene/MGI:109527#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-602#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9R283-1", "protein_name": "Short transient receptor potential channel 2", "gene_name": "Trpc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLMSLTDSKEGKNRSGVRMFKDDDFLIPASGESWDRLRLTCSQPFTRHQSFGLAFLRVRSSLDSLSDPVKDPSSPGSSGLNQNSSDKLESDPSPWLTNPSIRRTFFPDPQTSTKEISALKGMLKQLQPGPLGRAARMVLSAAHKAPPASVVSPNNSHGEPDSSHPERAEPRAEEPNRKNNASRGKRRKVQEQRRPLSSSSSQPNRRATGRTKQRQQRPQAKSDGSGVQATGQCPICTGSFSIEALPRHAATCGESSPPQPASPTSLSSSESVLRCLHVALTPVPLIPKPNWTEIVNKKLKFPPTLLRAIQEGQLGLVQQLLESGSDPSGAGPGGPLRNVEESEDRSWREALNLAIRLGHEVITDVLLANVKFDFRQIHEALLVAVDTNQPAVVRRLLARLEREKGRKVDTKSFSLAFFDSSIDGSRFAPGVTPLTLACQKDLYEIAQLLMDQGHTIARPHPVSCACLECSNARRYDLLKFSLSRINTYRGIASRAHLSLASEDAMLAAFQLSRELRRLARKEPEFKPQYIALESLCQDYGFELLGMCRNQSEVTAVLNDLGEDSETEPEAEGLGQAFEEGIPNLARLRLAVNYNQKQFVAHPICQQVLSSIWCGNLAGWRGSTTIWKLFVAFLIFLTMPFLCIGYWLAPKSRLGRLLKIPVLKFLLHSASYLWFLIFLLGESLVMETQLSTFKGRSQSVWETSLHMIWVTGFLWFECKEVWIEGLRSYLLDWWNFLDVVILSLYLASFALRLLLAGLAYMHCRDASDSSTCRYFTTAERSEWRTEDPQFLAEVLFAVTSMLSFTRLAYILPAHESLGTLQISIGKMIDDMIRFMFILMIILTAFLCGLNNIYVPYQETEKLGNFNETFQFLFWTMFGMEEHSVVDMPQFLVPEFVGRAMYGIFTIVMVIVLLNMLIAMITNSFQKIEDDADVEWKFARSKLYLSYFREGLTLPVPFNILPSPKAAFYLLRRIFRFICCGSSCCKAKKSDYPPIPTFTNPGARAGPGEGEHVSYRLRVIKALVQRYIETARREFEETRRKDLGNRLTELTKTVSRLQSEVASVQKTVAAGGALRPPDGASILSRYITRVRNSFQNLGPPAPDTPAELTMPGIVETEVSLEDSLDATGEAGTPASGESSSSSSAHVLVHREQEAEGAGDLPLGEDLETKGES", "length": 1170 }, "evidence": [ { "id": "RGD:7692537", "url": "https://alliancegenome.org/gene/RGD:7692537#orthology", "database": "AGR" }, { "id": "MGI:109527", "url": "https://alliancegenome.org/gene/MGI:109527#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-602#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "inositol 1,4,5 trisphosphate binding", "id": "GO:0070679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070679", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1M8" } ], "pmid": "" }, { "name": "store-operated calcium channel activity", "id": "GO:0015279", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015279", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1M8", "url": 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. 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"https://www.uniprot.org/uniprotkb/A0A8M6Z1N9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017206746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206746" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1N9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ftr73", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090508-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090508-13", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z1N9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z1N9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19769", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19769", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "798459", "url": "https://www.ncbi.nlm.nih.gov/gene/798459", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:798459", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798459", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1N9", "url": "https://www.orthodb.org/?gene=A0A8M6Z1N9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "X1WHK1", "url": "https://www.orthodb.org/?gene=X1WHK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017206746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206746", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1N9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X1WHK1", "url": "https://www.uniprot.org/uniprotkb/X1WHK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X1WHK1-1", "url": "https://www.uniprot.org/uniprotkb/X1WHK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090508-13", "url": "https://zfin.org/ZDB-GENE-090508-13", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MCLHVADCFEASAKMSESSSSEYVDQFSCPVCLDLLKEPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCRESFSQRPLLKKNTLIAEMMETLQKTALQTPAAAAVDCDVCTTEKNRAVKSCLQCLASFCQTHLQLHYESPAFMKHKLVDASRHIQENICPSHGRPLEIYCQDDHQCICCMCTDNHKGHSVVSVDSEWTSKKEELEEMKLKCLKLIKDREKGQQDLSKATKNLKSSADEAVERMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFKDVPSFTSHTHLSFKDLSISAFREALEDACQQQTDAISREVSNVHVVQTPQPKSEHDFLQYYCKLQMDSSTAHRELKLSEEKRKVSFSDEVQPYPDHPQRFDWFHYILCREGLTGRCYWEVECSGDIWGVAVCYRGIRRKGNSDDCKLGFNKVSWRLNRLQQNITYIRNKVQVRIKAGCFSRIGVYLDHRAGILSFYSVSDTNTLLYKVQTTFTEPLYPAFIIGQGSSVRIFDKRTAQMEELT", "length": 567, "header": "tr|A0A8M6Z1N9-1|A0A8M6Z1N9_DANRE Isoform 1 of E3 ubiquitin/ISG15 ligase TRIM25 isoform X1 OS=Danio rerio OX=7955 GN=ftr73 PE=4 SV=1 CANONICAL=A0A8M6Z1N9-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9/entry#A0A8M6Z1N9-1", "sequence": { "sequence": "MCLHVADCFEASAKMSESSSSEYVDQFSCPVCLDLLKEPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCRESFSQRPLLKKNTLIAEMMETLQKTALQTPAAAAVDCDVCTTEKNRAVKSCLQCLASFCQTHLQLHYESPAFMKHKLVDASRHIQENICPSHGRPLEIYCQDDHQCICCMCTDNHKGHSVVSVDSEWTSKKEELEEMKLKCLKLIKDREKGQQDLSKATKNLKSSADEAVERMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFKDVPSFTSHTHLSFKDLSISAFREALEDACQQQTDAISREVSNVHVVQTPQPKSEHDFLQYYCKLQMDSSTAHRELKLSEEKRKVSFSDEVQPYPDHPQRFDWFHYILCREGLTGRCYWEVECSGDIWGVAVCYRGIRRKGNSDDCKLGFNKVSWRLNRLQQNITYIRNKVQVRIKAGCFSRIGVYLDHRAGILSFYSVSDTNTLLYKVQTTFTEPLYPAFIIGQGSSVRIFDKRTAQMEELT", "length": 567, "header": "tr|A0A8M6Z1N9-1|A0A8M6Z1N9_DANRE Isoform 1 of E3 ubiquitin/ISG15 ligase TRIM25 isoform X1 OS=Danio rerio OX=7955 GN=ftr73 PE=4 SV=1 CANONICAL=A0A8M6Z1N9-1" }, "locus": {} }, { "isoform_ac": "X1WHK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9/entry#X1WHK1-1", "sequence": { "sequence": "MSESSSSEYVDQFSCPVCLDLLKEPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCRESFSQRPLLKKNTLIAEMMETLQKTALQTPAAAAVDCDVCTTEKNRAVKSCLQCLASFCQTHLQLHYESPAFMKHKLVDASRHIQENICPSHGRPLEIYCQDDHQCICCMCTDNHKGHSVVSVDSEWTSKKEELEEMKLKCLKLIKDREKGQQDLSKATKNLKSSADEAVERMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFKDVPSFTSHTHLSFKDLSISAFREALEDACQQQTDAISREVSNVHVVQTPQPKSEHDFLQYYCKLQMDSSTAHRELKLSEEKRKVSFSDEVQPYPDHPQRFDWFHYILCREGLTGRCYWEVECSGDIWGVAVCYRGIRRKGNSDDCKLGFNKVSWRLNRLQQNITYIRNKVQVRIKAGCFSRIGVYLDHRAGILSFYSVSDTNTLLYKVQTTFTEPLYPAFIIGQGSSVRIFDKRTAQMEELT", "length": 553, "header": "tr|X1WHK1-1|A0A8M6Z1N9_DANRE Computationally mapped isoform of E3 ubiquitin/ISG15 ligase TRIM25 isoform X1 OS=Danio rerio OX=7955 GN=ftr73 PE=4 SV=1 CANONICAL=A0A8M6Z1N9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:798459", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798459", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1REU8-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr65", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEFSVSVAQDQFSCAVCLDLLNDPVSIPCGHSYCMSCITDCWNKKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQEIHPGNQHQLTEATHRLKEMICPQHEKLLEIFCRTDHCCICYLCLVDQHKHHDTVSAAAERTELESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSITVSFPLDFDDIVKSVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTVNNWLVLSEGNTAVENKGSVQPYPDHPDRFDYWRQVLCRESVCGRSYWELEWSGARVFLSVSYKSIKRKGRGNECLFGRNAQSWSLSCSAESFSFRHNNKNTELPKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTNTLCPGFYVYKGSKVKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RFB3-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr14l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRSSTASQSRYGTQEKPRRSGRYSSSSSRSSSRDVLCDFCMIKKNKAVKSCLTCLTSFCEAHLQAHYEYPALMKHKLVAATGQLREKICGEHDKLLEVFCRSDQMCVCVLCIMEEHKKHDIVSAAAERTEKQKQLGAKLMTSQQKIEERMKKWQDLRQAVASLKHSSQSVLDENERIFAELLRALERRHGEVKEMIRAQEVLLLTNAERHLARLEEEITLLRKKHTDLEQLSQSDDHIHFLQSWQSLSAPSGYEDLSKVTLAPHHTFDNAKKAISDLKVQMEDISKEELNKISSAVNEVKILQTVDPAKREEFFEYSCQLSIDPLTAHPNLVLSDRNTVVQMSNEPRPYPDHPDRFDYWQQALCKPGLAGGRYYWELDWRGTEVDIAVTYKGIQRKGNDKPGSFGRNDKSWSLYCSESEYSFMHNSKSTAVSVPRSSRIGVYVDYESGTLAFYSVSDKMTLLYKVQTKFTEPLYPGIGVWGYGTTVRL", "length": 489 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RJY4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr03", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDSSKMAAESSVSFAQDQFNCSICLDLLKDPVAIPCGHSYCMSCISDYWDQDEWRGVYSCPQCRQTFTPRPALGKNTMLTEVVENIRKRKLQAGDVECDVCIGKAVKSCLVCLESYCQTHFEQHEEFHSRKRHKVTDANGRLQEMICPQHDRLLEMYCRTDQRCICMLCLMNEHKTHETVLPAEERAEKQKHFNEKLQQRIQEKQKQCEELRAAVESHKRSVQAAVEDTERIFTELIRSIERSRSKVTQLIRDQGKASVSGAEGRLEQLEQEINDLRRRNTELEQLSCTDNDIHFLQSFQSLSVPPASTDSSSISSRLSFNKFKMFVSRVKEELQNSLKDEKENISRIVRNISVLPTPEYERRKKFLQYYQQLTLDSNTAYKSLRLSEGNRVVTRMKKTSNHPDRFDGFAQLLCKESVRGRCYWEVERSGKGMYVSVSYKSIRRKGQGSECKFGCNDQSWSLYCSDTKCSFRHNNEESKLPVVSSSSRIGVYVDHSAGTLSFYSVSDTMSLIHRVHTTFTQPLYPGFGVSNESQVKLCDQA", "length": 542 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RKP5-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr76", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSESSSSECVDQFSCSVCLDLLKEPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCRESFSQRPLLKKNTLIAEMMETLQKTTLQTPAAAATAVDCDVCTTEKNRAVKSCLQCLASFCQTHLQLHYESPAFMKHKLVDASRHIQENICPSHGRPLEIYCQDDHQCICCLCIINSHKTHSVVSVDSEWINKKKELEKIAVERLKLIENREKGLWELSEAVKSFKSSADEAVEKMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIHKLLTTEDQIHCLKSCESVCVLPTFEEVPFSPHSHLSFKDLSISAFREALEDACRQQTDAISREVSNVHTVKPSEPKTYNDFLQYFYQPHLDPNTAHKNLILSEENRRISYSDTDQQYPDHPERFAAYCNVLCKEGLTGRCYWEVNCHGKIWAVAVCYKGISRKGNTDDNILGYNKQSWRLSRYQKNIFFVHNSEEVSIPVFHSSRIGVYLDHRAGILSFYSVSKTMTLIHKVQTTFTELLYPAFGLGECSIRIIKQKRFLKDQK", "length": 553 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" }, { "id": "MGI:102749", "url": "https://alliancegenome.org/gene/MGI:102749#orthology", "database": "AGR" }, { "id": "HGNC:12932", "url": "https://alliancegenome.org/gene/HGNC:12932#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RLP4-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25 isoform X1", "gene_name": "ftr02", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAQDQFNCSICLDLLKDPVAIPCGHSYCMCCISGYWDQDEQKGVYSCPQCRQTFTPRPALGKNTMLVEVVEKLRKRKLQAARPAQCYSESADVECDVCTGDKNKATKSCLMCLNSYCQNHLEQHETFFKIKRHNLMDATGRLQEMICPQHEKLLGIFCRTDKRCICYLCTMDEHKTHDTVSAAAERTDKQKYFEETLKKRIMENQKEREELRAALESHKRSVQATVEDTERIFTELICSIERTRSEVTQVIRDQEKAAVSGAERRLKKLEQEIDDLKRRNTELEQISNTDNHIHFLQNFQSFSVPPESTDTSIRSRLSFDDLVTFVSQVKEKLQQTVKQEQKNIFHIVRHINVMPSPQNKSRNDFLQYYKRFTLASNTAHESLKLSEGNRVVTRAKNALFSFPDIFEDLTQVLCNESVSGCCYWEVEWSGRGMCASVAYKSISRKGPGYDCRFGHNDQSWGLYFSDFSCSFWHNNIHTKLPGVSSSSRIGVYVDHSTGTLSFYSVSGRMRLIHRVYTTFTQPLYPGFGVCHDSQLKLCD", "length": 546 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RLR7-1", "protein_name": "Tripartite motif-containing protein 16 isoform X1", "gene_name": "ftr33", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSKMAESSVSLAHREFSCSVCLDLLKDPVAIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQQLNPGNRHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISRRVSSISIIPAPEPQTREQFLQYSQQFTLDPNTAHTYLVLSEGNTAVENKGSVQPYPDHPDRFDCWRQVLCRESVCGRSYWELEWSGVDVLISVSYKSISRKGSGNECLFGLNDQSWSLCCSADSFSFRHNNINTDLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFWVCSRLKLCDLTV", "length": 561 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RN91-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr36", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFCPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQELNPGNQHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTELESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTANNRLILSEGNTVVDCKGSVQPYPDHPDRFDGWFQVLCKESVCRRSYWELEWSGNGVEIAVSYKSISRKGSILECRFGLNDQSWSLFCSVHSFSFWHNNKQTQLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHALYPGLCLYSRVKLCDLTV", "length": 556 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2B8U3-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr57", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEVRFSLEEFMCPVCLDLLKDPVTIPCGHSYCKTCITGCWDQEDDKRVYSCSQCREAFNPRPALAKNTILAEMVEKLKTKPPADCYAGAGDVQCDVCTGIKYKAIKSCLVCQESYCRTHFDRHEEFHSRKPHKVIDATERLQDMICRKHEKELEMYCITDQMCICLMCKEYEHKNHETMSTAAQRTEKQKELKETQMKLQQRVQQRQKDLQQLREAVESQKRCAQTAVEDTDRIFTEIIRLIERRRSELTQMIRDQQKTAVSEAEGLMKRLEKEIDHLRRRGAELEQLSHTQDHIHFLQSFQSLSAPPESTDVSFNPLLSFDDLKESVQQLKVKLEDFCKEEIRKTSDKGTPILNDPFKDTFANIVPKTTRDFLKYYSRFTLDLNTVNKYLCLSSNMITYTNTPQPYPDHPDRFDQLCQVLCRESVSGRCYWEIKWSGYGVCISVSYKGIRRKGQGKDCIFGGNDQSWCLFCYPGDYSFIHNDLKTVLPVQSISSRVGVYVDHSAGILSFYSVSNTMTLIHKVQTTFTQPLYPGFNVNGYKSSVILC", "length": 548 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAS0-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr26", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSTSVVEDQFSCSICKDLLREPVTIPCGHSYCMICITDCWSQDEQRRVYSCPQCRQTFTPRPALNKNVVMAEMVENLKKTGLKSRANYAEAGDVKCDVCAGRKRKAVKSCLLCLNSYCETHFECHEVFHSSKRHKVTDATGRIQEMICSQHDRLLEVYCRTDQKCVCLMCVMDEHKNHDTVSAEAERAEKQIQVGETQTQLQNRIQEKQSKLQQLRESVEIHKSSAQTAVDDCERIFTEIIRCIKRRRLKVTQMIRDREKTEVSRAEGLLKKVEQEIEDLKRRNTELEQLSHTDDHIHFLQSLQPLIIPAESTDSMTVSSLPSYEDVGKSVSELRKKLDDFCKEQIKLISASVSCRTQILPTTKPKTREDFLKYFHQFTLDSQSVHNNLSLSDENRVATFTASMHAYPDHPDRFDTWPQVLCRENVCGRCYWEVEWSGNHGVAIAVSYKSISRKGQGTECKFGYNDQSWRLFCSASGYIFSHNNRKRDLPVVSKIGVYVDQRAGVLSFFRVSDTKMSLIHRVQTTFTQPLYPGFGLNRDSSVKLSSMI", "length": 551 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAU1-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr34", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNQHKVTEATHKLQEMICPQHEKPLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTEQESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFFISSQLSFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISIIPAPEAQTHEQFLQYSQQFTLDPNTAHNRLVLSEGNTAVENNWSVQPYPDHPDRFDGYSQVLCRESVCGRSYWELEWSGNGVEISVSYKSISRKGSGNECLFGRNDQSWSLCCSPLSLSFYHNNINTKLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFYVNYSSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAX9-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr35", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHNYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNRHKVTEATHKLQEMICPQHEKPLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTEQESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEIEMISSRVSSISIITAPEPQTREQFLQYSQQFTLDPNTAHKYLVLSEGNTAVEDKDSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGDGVYLSVSYKSISRKGSGNECGFGHNDQSWSLCCSDYSFSFRHNNIKTKLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLMHTLHTTFTHTLYPGFCVYYSSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQJ4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr95", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCAVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHQGNRHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTAYNRLVLSEGNTAVENKRSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGEDVEISVSYKSISRKGLGNECVFGFNDQSWSLSCSAHSFIFYHNNIKTDLRKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFRVYVCSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B808-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr29", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAHHEFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFCPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHQGNRHKVTEATHKLQEMICPQHEKLLEIFCRTDHCCICYLCLVDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSPLVFDDIAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTAYNRLVLSEGNTAVENKRSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGEDVEISVSYKSISRKGSGNECVFGFNDQSWSLSCSAHSFIFYHNNIKTDLRKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFRVYVCSRLKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YUU8-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSVAHREFSCAVCLDLLKDPVSTACGHNYCMSCITNCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEMVEKLRKSKLQAAGPAQSPAASGDVECDVCSGAKNRAVKSCLVCLNSYCHTHFQLHQQLNPGNQHKVTEATHRLKKLICPQHEKPLEIFCRTDHCCICYLCTMDQHKNHNTVSAVAERTEQQRRLKNIQSSFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLSFNKVTESVSRLRDKLQQFCTEEMKTISSRVSSISIIPAPEPQTREQFLQYSQQFTLDPNTAHTYLVLSEGNTAVENKGSVQPYPDHPDRFDCWHQVLCRESVCGRSYWELEWSGVDVLISVSYKSISRKGSGNECLFGLNDQSWSLCCSADSFSFYHNNIKTDLPKPSVSSSRRGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFCVYYSSRLKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YW98-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEAGISWSQNQFSCSICLDLLKGPVTIPCGHSYCMRCISGYWDQDKQRGVYICPQCRQTFTPRPALGKNTMLAEVVEQLKKTKLQAARPAHCYSESADVECDVCTGDKNKAVKSCLVCLNSYCQNHLEQHESFFRGKRHNLMDATGRLQEMICPQHDKLLEVFCRTDQCCICLLCVDEHKNHEIVSATAERTDKQRQLEETQSKHNQRIQRKQEECVELRVAIESQKCSAQAAVEDTERIFTDLIRSIERRRSEVTQLIRDQEKAQVSAAEGRLERLKQEIDDLRRRDAELEQLSHTDHHIHFLQSFQSLSTPPGSTDSSSITVSSSLSFDDVGKSVSRLREKLEDFCREEIEKISVRGITSIQKPELKTREDFLQYYRPLTLDPNTVNNCLVLSEGNRVFEHTSTNQQYPDHPDRFDCFLQVLCRENVYGRCYWEVEWSGDVEILVAYKSISRKGLGDECGFGRNDQSWGLSCSRSRCSFCHNKKQTKLPVMSNSSRIGVYVDHSAGTLSFYSISNTMSLIHRVHTTFTQPLYPGFGIDSLYSLFSETKQKIKLSDLKI", "length": 561 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PAX6-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEGRFSVDQNKFDCPICLDLLKEPVTIPCGHSYCMNCITDCWSQDEQRRVYSCPQCRQTFTPRPALNKNVVMAEMVENLKVTKVKTTDPAPSYAGPGDVECDVCTGIKYKAIKSCLLCLESYCQTHFERHEAFRTGKRHKITDASGRIQEMICLKHDKLLEVYCRTDQKCICLLCTMDEHKNHDTVSSSSERTEKQKHLEDTQRNLQQKIQEREKKIQVLKESLKTHKSSAQTAVEDSERTFTELIQSIERRRSEVTQMIRDREKTEVSLTEGLLKKLEQEIEDMKRRNTELEQLLHTDDHIHFLQRFQSLSKPLESTDLSSTAVSSGFRYEDVSKSVSQLKIKLEQICTEDIENIHGQARKMIFSALLSTSHTEPTTRKDFQQYFQQLSLDQNTAHQQICLTEDNTVATWTDRVQQYPDHPDRFDKFFGVLCRESVSGRCYWEVEWSGNERLYGVGVAVSYKTINRKGDMTTSGFGFNDQSWRLFSFKSRYTFLHDSKQTELSVVSRSSRIGVYVDHRAGILSFFSVSDTTMSLIHRVQTTFTQPLYPGFWINKGSRVKICHI", "length": 565 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PJ13-1", "protein_name": "Tripartite motif-containing protein 16 isoform X1", "gene_name": "ftr11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVCLAQEQFSCSICLDLLKDPVAIPCGHSYCMSCISDCWDQDERKGVYSCPQCRQTFTPRPALGKNTMLTEVMENIRKRKLQAGDVECDVCTGRKFKAVKSCLVCLESYCQTHFQHHEEFHSRKRHKVTDATGRLQEMICPQHEKLLEIFCRTDQCCICYLCTMDKHKNHDTVSAAAEWTDKKIQLAEMQKTTHQRMVERQKEREELRAAVESHKRSAQAAVEDTESIFTELIFSFERSCSEVTQLITDQQKAAEGRAEERLKQLEQEINDLRRRNTELEQLSHTDHHIHFLKSFQSLSSPPGSTDSSSITVSSRISFDDVGKLSHLRKKLEQFCREEIEKISSKVRDINIISISAEPKTRQEFLQYSRQLTFDPNTVNTSLVLSKKNRVIEYTDKVQQYPDHPDRFDCWPQVLCRESECGRFYWEVEWNGYIEISVSYKSISRKGRGNECVFGCNDQSWSLFCSRSRFSFRHNKQQTKLPVLSISSRIGVYVDHSAGTLSFYNVSDTMSLIYRVHTTFTQPLYPGFWVFAGSILFTTDTL", "length": 545 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PRK9-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr41", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEVRISVDQIEFMCPVCLDLLKDPVTLHCGHSYCKSCITDFWDQEYEKRIYSCPQCRQSFTPRPALAKNTMLAEVVEKLKKTKPPADCCAGAGDVQCDACTGRKYKAVKSCLQCQESYCQTHFERHEEFHSRKPHKVIDATGQLRDMICQKHGKELEIYCITDQQCICELCKEYEHKNHATVSTAEQMTEKQQELKERQVKLQQREKALRKLKNAVESQKRSAQTAVEDTEKIFTELIHSIQKKGTELTQVISSAEKTAVSQAEEHMEYLEQEIEDLRRRNAELERLSQTQEHVNFLQRFQSLPAPLESTDGYFSSFLCFDAMKESVHELKSKLENLCKEEIKMILDRVTSFVPKTRNDFLQYSIKLTLDLHTAHKCLSKKRKVVTCTKKEQPYPDHPDRFHDWPQVLCTERVRGRRYWEVEWSGDKGVCISASYKSISRTGTGNECAFGGNDHSWSLFCSPLRYLFWHNNIQSDLTVKPNSHKIGVYVNVGAGTLSFYNVSDEMSLIHTFQTTFTQPLFPGFTVGFGSSVKLKHR", "length": 537 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6I4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr94", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEARFSQDEFLCPVCLELLKDPVSLHCGHNYCKGCISGFWDQEDEKRVYSCPQCRQTFSQRPALAKNTMLAEVVEKLKKTKPPADCKAGAGDVQCDVCTGTKYKAIKSCLQCQESYCQTHFENHEEFHFRKSHKVIDATGQLQDMICQKHKKELEIYCITDQQCICELCKEFEHTTHETLSVAEQRKEKQKELKETQVKLQESLQQRQQELQQLREAVESHKRSAQTAVKDTERIFTELICSIEKRCSELTQIIRDQEKTAVSRAEGHMEWLEQEVENLRRRNAELEQLSHKKDHVQFLKSFQSFSAPPESTDVLSSSLLCFDGLSESVSQLKDKLEDFCKKELKKISDRVTKTSPKTRNDFLQYSHQFTLDLNTMNDHLRLSESNRVITGAETAQPTFDHPDKFNGWPQVLCRESVRGRCYWEIEWSGDVGVILSVSYKSISRKGFGNECAFGGNDKSWSLACFPTRYSFWHNSKRTDLSVKPISRMIGVYVDESAGILSFYGISNTISLIHTVKTTFTQPLYPGFTVDPRSSVKLC", "length": 539 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TBM3-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr37", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSVAHHEFSCAVCLDLLKDPVSTACGHNYCMSCITNCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNQHKVTEATHKLKKLICPQHEKPLEIFCRTDQLCICYLCTMDQHKNHNTVSAVAERTEQQRRLKNIQSSFQQRLQERQKELEKLKKAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSPLVFDDIAESVSHLREDLEHFGKKEIKLISRRVSSISRIPAPVPKTREQFLQYSQQFTLDPNTVNNWLVLSERNTVVKYKGSVQRYPDHPDRFNCWYQVLCRESVCGRSYWELEWSGVDVYLSVSYKSISRKGSGNECLFGYNDHSWSLWCSADSFIFYHNNKQTKLPKPSVSSTRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHALYPGFCVHYSSRVKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UV20-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X1", "gene_name": "ftr91", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESMLSQQKDQFSCSVCLDPLKQPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCREIFRQKPLLKKNTLIAEMMETLQKTALQTPAAAVDCDVCTTEKNRAVKSCLQCWASFCQTHLQLHYKSPAFMNHKLVEASRHICPNHKKPQDIYCQDDHQCICYLCMIDSHKGHRVVSVEAELINKKNKLKEMKLKCQTLIKERQRGWQELSIAMKLFKSSADEAVEKMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFEDVPSFTSHTHLSFKDLSFSAFREALEDACQQQTDAISREVSNIHVVKPPDLKTQNDFLQYFCQIHLDRNTAHKNLKVTEDNKKVSCSDKDQKYPDHPERFDGYCHVLCREGLTGRCYWEVECSGKYWAVAVCYRGISRKGVSDDCKLGFNKISWRLGYYLQNFSFIHGKAHVRLPPASRIGVYLDHKAGMLSFYSVSDTMTLLHRVQTTFTEPLYPAFYSGSGSSVKIIE", "length": 537 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" }, { "id": "MGI:102749", "url": "https://alliancegenome.org/gene/MGI:102749#orthology", "database": "AGR" }, { "id": "HGNC:12932", "url": "https://alliancegenome.org/gene/HGNC:12932#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UV86-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr38", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAHCKFSCSECLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQELNPGNQHKVIEATHRLKEMICQQHKKLLEIFCRTDHCCICSLCVLDGHKNHDTVSAAAQRTKKQCRLKKTQSRFQQRLQERQKELEELREAVESHKHSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSFQSLSVPPGSTDSSSFFISSQLSFNKVTESVSRLSDKLQQFCTEEMKTISDKVRFISIIPAPEPQTREQFLQYSQQFTLDPNTVNKKLVLSEGNTAVEINGSDQPYPDHPDRFDGFSQVLCKESVCGRSYWELECSSASVYLSVSYKSISRKGSGNECRFGNNDQSWSLFCSDNSFSFWHNNIKTDLRKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFYVYLAKVKICDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UVE5-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAECSISVAQDQFSCSICLDLLKDPVAIPCGHSYCMSCISDCWDQDEQRGVYSCPQCRQTFTPRPALGKNTMLAEVVGKLKKTKLQAARPAQCYSESADVECDVCTGDKNKAVKSCLMCLNSYCQNHLEQHASFFRSKKHNLMDATGRLQEMICPQHDKLLEVFCRTDQCCICYLCTMDGHKNHNTVSAAAERTDKHRQLEETQSKLHQRIQRKQVEFEELRAAVESHKCSAQAAVEDTERIFTDLIRSIERSRSEVTQLIRDQEKAAVSEAEGRLERLEQEIDDLRRRDAELEQLSHTDHHIHFLQSFQSLSTPPGSTDSSSITVSSSLSFDDVGKSVSRLREKLEHFCREEIEKITWRMRDYKGTTPTPEPKTHQEFLQYTCWLFLDLNTMNKNLVLSKGNRVIELSSTVQQYPDHPDRFDCWHQVLCRESVCGRCYWEVEWSGSVGISVAYKSIGWKGQGTEFGYSNQSWCLFCSGSICTFVHKSKHTVLPLVSSSSRIGVYVDHSAGTLSFYSVSDTMSLIHRVHTTFTQPLYPGFELVSYNPCGSKLKLCEL", "length": 557 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58GXY0-1", "protein_name": "FinTRIM family, member 23 isoform X1", "gene_name": "ftr23", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGFSETGKCSPTLLSEMAESSISVAEDQFSCSVCLDLLKEPVTIPCGHSYCMNCITDCWNQDEQRRVYSCPQCRQTFTPRPALNKNVVMVEMVEKLKTGSRNAASYAGPGDVECDVCTGRKRKAVKSCLMCLSSYCQTHLEQHDSFFKDKRHHLINATGRLRQMICSKHDRLLEVYCHTDQKCICLLCMMDEHTGHQTVSIKTERAEKQKQLLDLQKNFQKTIQEREEEVWDLKHAVKTHKHSAQTAVEESERIFTRLFHFIERRQSEVSQMIRDRKKTEVSRAEGLLKKLEEEIEDLKRRNTELEQLSHTDDHIHFLQSFHSLSAPPESPESSDVTSLLFYDDVGETLSVLKEKLEDACKEATENMSVLETPYMEIVSTSELINRDKFLQYFHHLTLDSNTAHKYLRLSEGNRVATFIGADQSYPAHPDRFHDFSQVLCRESVCGRCYWEVEWSGEAGVGISVSYKSIRRKGEGFDCVFGFNDQSWRLSCSNSRYTLRHKQLSTKLRVPSGSNRIGVYVDHKAGILSFFNISDTMSLIHRVQTTFTQPLYPGFGINFGSTVKLKSAENL", "length": 570 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58I1B9-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X2", "gene_name": "ftr30", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTHTGSVRAERNRKFTQIPCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKQQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQQLNPGNQHKVIEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEAQTREQFLQYSQQFTLDPNTVNNCLVLSEGNTAVDYKDSVQPYPDHPDRFDCSYQVFCRESVCGRSYWELEWSGVVYLSVSYKSISRKGRNIECGFGNNDQSWSLECSPYSFSFWHNKIKTALPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFGVYSSRLKLCDLTV", "length": 562 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ACD6B7A1-1", "protein_name": "LOW QUALITY PROTEIN: tripartite motif-containing protein 16", "gene_name": "ftr42", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAETRFSQDEFLCPVCLDLLKDPVAIHCGHSYCKSCITDFWNMEDEKGIYSCPQCRQTFSPRPALAKNTMLAEVVDKLKKTTPPADCYAGAEDVQCDACTGTKYKAIKSCLQCLESYCQTHFERHEEFHSRKPHKVIDATGRLQDMICPKHEKELEVYCITDQQCICELCKEYEHKNHKTVSAAAQRTEKQKELKETLVKLQERLQQRQKDLQQLRAAVESHKQSAQTAVEDTDRIFTELIYSIEKRRSELTQMIRDQEKTTRSRAERHMEQLEQEIEDLRRRNTELEQLSHTHHHIHFLQSFQSLSAPPESTDVSFSSLLCFDGLRESVSQLKVKLEDFCIEEIEKFTERVTKTVPKTRNDFLQYSHKLTLDLNTAHKLLHLSERNRIIICTETEQPYPDHPDRFDSWRQVLCRESVRGRCYWEIEWSGIKGVCISVSYKSISRKGFGNECVFGGNDQSWGLFCSTSRYSLWHNKKRSDLPLKPISRRIGVYVDVGAGTLSFYSIFDTMSLIHTVQTTFTQPIYPGFTVDPRSSVKLC", "length": 539 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A9N5-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "Trim25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAELFPLAEELSCSICLEPFKEPVTTPCGHNFCRSCLNETWVVQGPPYRCPQCRTVYQVRPQLHKNTVLCAVVEQFLQAEQARTPVDDWIPPTRSAASSSDTQVSCDHCLKEVAVKTCLVCMASFCQEHLRPHIDSPAFQDHPLQPPVRDLLRRKCSRHNRLREMFCPEHGECICHICLVEHKTCSPTILSQASADLENKLRQKLTIMYSHINGASKALEDVKSKQQNVQESMKRKMLQLRQEYLEMKAVIDAAETSSTHKLKEEEKRVYGKLDTIYQVLLKKKNEMQNLKAEVELILAKGDEFEFLEKAAKLQEVSTKPVYIPKIDLDHDLIKGVYQGALDLKSELKLSLKQLQEKKAEEPCNSGNVGDHAQSTSKPTRPAKKTAPDKKTKKTPGAAGAAGAAGAAGAAGPTSYSSSSNKLPTFGAPGQATIPDATLKPNAPQPNSAAVKAKVLENFLTMSRTELLEYFVKVVFDYNTAHNKVALADNYTTASVADGLQHYRSHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGVCYGSMDRQGPESRLGRNPSSWCVEWFNNKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVTEKVYLMYKFKVDFTEALYPAFWVFSAGTTLSICSK", "length": 643 }, "evidence": [ { "id": "MGI:102749", "url": "https://alliancegenome.org/gene/MGI:102749#orthology", "database": "AGR" }, { "id": "HGNC:12932", "url": "https://alliancegenome.org/gene/HGNC:12932#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LMT9-1", "protein_name": "Tripartite motif protein 80", "gene_name": "Trim80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSAKLGSFLRKGHLDRETMKQQPQRTVRRRRSPVHRAAKYLAVIDMQKISRPTQDKSPSELSTQSSRTSLQLLMSSNSSQHLLEDQVLCPICLDVFRNPVTTACGHNFCMTCLQSFWDHQADTGETYYCPQCREAFPSRPRLCKNVILGEMVACFTLAKSQTSGPLWGLAGPTDVPCDFCSPQKLKATKSCLQCMASLCEKHLHSHFEDPLFQEHQLLDPVWDLKNRLCRKHRKLRQMYCRTEGSCVCGACLLEEHQNHDTTPLEDERARKEVEVRKIQANVENQMLIIASDSQKHQGRVSFLSKLIQTMREEVNTCFSEILHEVKQLQMKVLDFVENEETVALGMLGNSMQQSHSRLLKLEGDSVWLHGLLANKSDEQFLQEFPTLKHFPACVEPLLGTNCEETQSFLQLPETLAQLRIRLMDIGLNFINQLLLKGIRMNSYEVLPATVDRKTLLQNYCNLNFDSSMASEELFLFKETHSVLNLGILLEPSTTSPLPGFKQWPQVLCCPGLSEGCHYWETEVSDSWMCLGVTYRRNPSMSGRHRRNIVYLLGRNPYSWCLEWDSLKFSVWHNNTQTVLHGSYHHTLGVALDFRAGCLSFYGVAGDVSLLYRFLTSFLEPLYPAVMVSSGASLTLKQYPEA", "length": 642 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090508-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090508-13#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSICSPK", "length": 630 }, "evidence": [ { "id": "MGI:102749", "url": "https://alliancegenome.org/gene/MGI:102749#orthology", "database": "AGR" }, { "id": "HGNC:12932", "url": "https://alliancegenome.org/gene/HGNC:12932#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090508-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090508-13#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61510-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "Trim25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELNPLAEELSCSVCLELFKEPVTTPCGHNFCMSCLDETWVVQGPPYRCPQCRKVYQVRPQLQKNTVMCAVVEQFLQAEQARTPVDDWTPPARFSASSAATQVACDHCLTEIAVKTCLVCMASFCQEHLRPHFDSPAFQDHPLQSPIRDLLRRKCTQHNRLRELFCPEHGECICHICLVEHKTCSPTTLSQASADLEYKLRNKLTIMHSHINGATKALEDVRSKQQCVQDSMKRKMEQLRQEYMEMKAVIDAAETSSLRKLKEEEKRVYGKFDTIYQVLVKKKSEMQKLKAEVELIMDKGDEFEFLEKAAKLQGESTKPVYIPKIDLDHDLIMGIYQGAADLKSELKHSIKKLQKKSEEHNGSGNKGDQTQSTFKPVQPSKKTIQEKKTKKTPVAPGPPSHFSPNKLPTFGAPGQSLDSKATSPDAAPKASAAQPDSVGVKAKVLENFLTKSRTELLEYFVKVIFDYNTAHNKVSLSNKYTTASVSDGLQHYRSHPQRFTYCSQVLGLHCYKNGIHYWEVELQKNNFCGVGICYGSMERQGPESRLGRNPNSWCVEWFNNKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVTEKVHLMYKFKVDFTEALYPAFWVFSAGTTLSICSK", "length": 634 }, "evidence": [ { "id": "MGI:102749", "url": "https://alliancegenome.org/gene/MGI:102749#orthology", "database": "AGR" }, { "id": "HGNC:12932", "url": "https://alliancegenome.org/gene/HGNC:12932#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090508-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090508-13#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1N9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1N9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9" } ], "pmid": "" }, { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1N9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1N9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 487, "end_pos": 489, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z1N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 156, "end_pos": 195, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z1N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 369, "end_pos": 562, "start_aa": "His", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z1N9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1N9" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 72, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 487, "end_pos": 489 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z1Q8-1", "uniprot_ac": "A0A8M6Z1Q8", "uniprot_id": "A0A8M6Z1Q8_DANRE", "mass": { "chemical_mass": 60558.0, "monoisotopic_mass": 60558.0 }, "refseq": { "ac": "XP_017212528", "name": "uncharacterized protein ric3a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212528" }, "gene_names": [ { "name": "ric3a", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8" } ] }, { "name": "ric3a", "type": "synonym", "evidence": [ { "id": "XP_017212528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212528" } ] } ], "protein_names": [ { "name": "Uncharacterized protein ric3a", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein ric3a", "type": "synonym", "evidence": [ { "id": "XP_017212528", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212528" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017212528.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017212528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212528" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ric3a", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-160215-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160215-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z1Q8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z1Q8", "database": "AlphaFoldDB", "categories": [] }, { "id": "568632", "url": "https://www.ncbi.nlm.nih.gov/gene/568632", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:568632", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568632", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR21723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21723:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21723:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15361", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15361", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017212528", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212528", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-160215-1", "url": "https://zfin.org/ZDB-GENE-160215-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFSVISASSGQKRCRDVDVRHRLLCGVFSLSAIDMAISTCQKITFVSCLVLCMSLFLPRLFLPRVKKEAVRSDVGPGHLPPSRHIHSLSEDHDHWDTDSHYIKHYSPDAIASFKGVKKPNLLGQVIPVYGFGIFLYIIYLFVKLTSKDKPHRQGCRFPLLQSQYTFEEMPTCQLVQLQARMSEKAREKRISKVVHPSARSRRGTRRREERKLKQLKEISQMMRERQLREGATPEEEAEEAPYNADWEGYPDETYPEYKIPSRRRRYPSVILEEPDQVILTAEELAERMEKEEEVEEEETADDTCANEELNLEDNEEDEEDEEQEEEDEEEEEDEEEDIAEDQPCLPQSFDEDDEGLEYSDEREEKPSRRRQITFSDHRHVFHYPKGGAVGCKYETEEEEEHEGEEEEEGNEEDENGESEECEEEEEEEEEEEEEEQHDKEEHGEREEKEEEDPLMEAESLGFNDDVECDPDEQEVDLIDFLQTYQPEVTVISNKSESSKRQASGTLRMRHKKEKVKK", "length": 517, "header": "tr|A0A8M6Z1Q8-1|A0A8M6Z1Q8_DANRE Isoform 1 of Uncharacterized protein ric3a OS=Danio rerio OX=7955 GN=ric3a PE=4 SV=1 CANONICAL=A0A8M6Z1Q8-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8/entry#A0A8M6Z1Q8-1", "sequence": { "sequence": "MFSVISASSGQKRCRDVDVRHRLLCGVFSLSAIDMAISTCQKITFVSCLVLCMSLFLPRLFLPRVKKEAVRSDVGPGHLPPSRHIHSLSEDHDHWDTDSHYIKHYSPDAIASFKGVKKPNLLGQVIPVYGFGIFLYIIYLFVKLTSKDKPHRQGCRFPLLQSQYTFEEMPTCQLVQLQARMSEKAREKRISKVVHPSARSRRGTRRREERKLKQLKEISQMMRERQLREGATPEEEAEEAPYNADWEGYPDETYPEYKIPSRRRRYPSVILEEPDQVILTAEELAERMEKEEEVEEEETADDTCANEELNLEDNEEDEEDEEQEEEDEEEEEDEEEDIAEDQPCLPQSFDEDDEGLEYSDEREEKPSRRRQITFSDHRHVFHYPKGGAVGCKYETEEEEEHEGEEEEEGNEEDENGESEECEEEEEEEEEEEEEEQHDKEEHGEREEKEEEDPLMEAESLGFNDDVECDPDEQEVDLIDFLQTYQPEVTVISNKSESSKRQASGTLRMRHKKEKVKK", "length": 517, "header": "tr|A0A8M6Z1Q8-1|A0A8M6Z1Q8_DANRE Isoform 1 of Uncharacterized protein ric3a OS=Danio rerio OX=7955 GN=ric3a PE=4 SV=1 CANONICAL=A0A8M6Z1Q8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:568632", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568632", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B0B1T9-1", "protein_name": "RIC3 acetylcholine receptor chaperone", "gene_name": "Ric3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAYSTVQRVALASGLVLAVSLLLPKAFLSRGKRPEPPPGPEGKLGRFPPMMHHHTAPSDGQTPGAHFQRSHLAEAFAKAKGAGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLSKGKTAEDRNCSTAPPGNTHRKITNFELVQLQEKLKETEEAMEKLINRVGPNGESRAQTVTSDQEKRLLHQLREITRVMKEGKFIDTSPEKEAEEAPYMEDWEGYPEETYPIYDLSDGIKRRQETILVDYPDPKEPSAEETAEQMGALDEESSEHLSWDRLPTDPGVQRDNSVTLCDPKPESCSCCFHEDEDPAVLAENAGFSADGYSEQEEATKENLPQDFTDEGLGTSTDNTHVGGMLRKRSPQGFE", "length": 367 }, "evidence": [ { "id": "RGD:1588939", "url": "https://alliancegenome.org/gene/RGD:1588939#orthology", "database": "AGR" }, { "id": "MGI:2443887", "url": "https://alliancegenome.org/gene/MGI:2443887#orthology", "database": "AGR" }, { "id": "HGNC:30338", "url": "https://alliancegenome.org/gene/HGNC:30338#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-160215-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160215-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z5B4-1", "protein_name": "Protein RIC-3", "gene_name": "RIC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAYSTVQRVALASGLVLALSLLLPKAFLSRGKRQEPPPTPEGKLGRFPPMMHHHQAPSDGQTPGARFQRSHLAEAFAKAKGSGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLSKGKTTAEDGKCYTAMPGNTHRKITSFELAQLQEKLKETEAAMEKLINRVGPNGESRAQTVTSDQEKRLLHQLREITRVMKEGKFIDRFSPEKEAEEAPYMEDWEGYPEETYPIYDLSDCIKRRQETILVDYPDPKELSAEEIAERMGMIEEEESDHLGWESLPTDPRAQEDNSVTSCDPKPETCSCCFHEDEDPAVLAENAGFSADSYPEQEETTKEEWSQDFKDEGLGISTDKAYTGSMLRKRNPQGLE", "length": 369 }, "evidence": [ { "id": "RGD:1588939", "url": "https://alliancegenome.org/gene/RGD:1588939#orthology", "database": "AGR" }, { "id": "MGI:2443887", "url": "https://alliancegenome.org/gene/MGI:2443887#orthology", "database": "AGR" }, { "id": "HGNC:30338", "url": "https://alliancegenome.org/gene/HGNC:30338#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-160215-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160215-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BPM6-1", "protein_name": "Protein RIC-3", "gene_name": "Ric3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAYSTVQRVALASGLVLAVSLLLPKAFLSRGKRPEPPPGPEGKLDRFPPMMHHHSAPSDGQTPGARFQRSHLAEAFAKAKGAGGGAGGGGSGRGLMGQIIPIYGFGIFLYILYILFKLSKGKTAEDRNCSTAPPGNAHRKITNFELVQLQEKLKETEEAMEKLINRVGPNGESRAQAVTSDQEKRLLHQLREITRVMKEGKFIDTSPEKEAEEAPYMEDWEGYPEETYPIYDLSDGIKRRQETILVDYPDLKEPSAEEIAEQMGEIEEEGSERLSWDHLPTDPGAQKDNSVAPCDPKPESCSCCVHEEEDPAVLAENAGFSADGYSEQEEATKENLPQDFTNEGLGVSTDNAHVGGMLRKRNPQGFE", "length": 367 }, "evidence": [ { "id": "RGD:1588939", "url": "https://alliancegenome.org/gene/RGD:1588939#orthology", "database": "AGR" }, { "id": "MGI:2443887", "url": "https://alliancegenome.org/gene/MGI:2443887#orthology", "database": "AGR" }, { "id": "HGNC:30338", "url": "https://alliancegenome.org/gene/HGNC:30338#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-160215-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160215-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "synaptic transmission, cholinergic", "id": "GO:0007271", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007271", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8" } ], "pmid": "" }, { "name": "protein localization to cell surface", "id": "GO:0034394", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034394", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8" } ], "pmid": "" }, { "name": "neuron projection", "id": "GO:0043005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043005", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1Q8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z1Q8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q8" }, { "id": "PF15361", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15361" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Resistance to inhibitors of cholinesterase protein 3 N-terminal", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 183, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 493, "end_pos": 495 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z1S2-1", "uniprot_ac": "A0A8M6Z1S2", "uniprot_id": "A0A8M6Z1S2_DANRE", "mass": { "chemical_mass": 58041.0, "monoisotopic_mass": 58041.0 }, "refseq": { "ac": "XP_017207310", "name": "extracellular tyrosine-protein kinase PKDCC", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207310" }, "gene_names": [ { "name": "pkdccb", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ] }, { "name": "pkdccb", "type": "synonym", "evidence": [ { "id": "XP_017207310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207310" } ] } ], "protein_names": [ { "name": "Extracellular tyrosine-protein kinase PKDCC", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2/entry#names_and_taxonomy" } ] }, { "name": "2.7.10.2", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2/entry#names_and_taxonomy" } ] }, { "name": "Protein kinase domain-containing protein, cytoplasmic", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2/entry#names_and_taxonomy" } ] }, { "name": "Protein kinase-like protein SgK493", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2/entry#names_and_taxonomy" } ] }, { "name": "Sugen kinase 493", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2/entry#names_and_taxonomy" } ] }, { "name": "Vertebrate lonesome kinase", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2/entry#names_and_taxonomy" } ] }, { "name": "extracellular tyrosine-protein kinase PKDCC", "type": "synonym", "evidence": [ { "id": "XP_017207310", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207310" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017207310.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017207310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207310" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1S2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "pkdccb", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-599", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-599", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z1S2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z1S2", "database": "AlphaFoldDB", "categories": [] }, { "id": "565254", "url": "https://www.ncbi.nlm.nih.gov/gene/565254", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565254", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565254", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1S2", "url": "https://www.orthodb.org/?gene=A0A8M6Z1S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46448", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46448", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46448:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46448:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12260", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12260", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017207310", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207310", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10596", "url": "https://www.rhea-db.org/rhea/10596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1S2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-599", "url": "https://zfin.org/ZDB-GENE-130530-599", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSKTRPLGVTAAHTYYTKLQYARTQSARVKYEQRRCRTLTVHKKDLPLKLAMTFQRSPFCAFVLLALLFLSLTLIVKKWHFGLQENEPFGDAARPDGSAPQRDTLRQQLQERQQELVLLDITFEDIQQQEGFNGKISLDNPTAADIGCEELGGVKAVDFLGSGYTKTVLKAALPNGLFVALKSVNHQGTDMRLCLDVFQDSQGCLELVSFKLRKEIVLLQKLQHPNIVELKGQCQDSILVGGITAVLEQGMPLQMIQLLQSPWEERFRVCLGLVRLLQYLSVSPLGSVALLDFQPRQFVMVSGELKLTDLDDASIHEPVCQEDSDCLLQFPLRNFTLRCSPAQTCKGLNEMRNLYNAYRYFFTYLLPHQAPPLLKPLIHHIMNATGDLKQSINETLIAFEKILHIYKSGLHLENLPTSITKDYAVLKGMRSVVNVEYRCWPSYRQQGCVLSVHSVREAAFICNSHTHCTSFSISSQTTWTGRLLASFRSGFSHLVPDVNSAVYMRRVKASGAVL", "length": 515, "header": "tr|A0A8M6Z1S2-1|A0A8M6Z1S2_DANRE Isoform 1 of Extracellular tyrosine-protein kinase PKDCC OS=Danio rerio OX=7955 GN=pkdccb PE=4 SV=2 CANONICAL=A0A8M6Z1S2-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2/entry#A0A8M6Z1S2-1", "sequence": { "sequence": "MSSKTRPLGVTAAHTYYTKLQYARTQSARVKYEQRRCRTLTVHKKDLPLKLAMTFQRSPFCAFVLLALLFLSLTLIVKKWHFGLQENEPFGDAARPDGSAPQRDTLRQQLQERQQELVLLDITFEDIQQQEGFNGKISLDNPTAADIGCEELGGVKAVDFLGSGYTKTVLKAALPNGLFVALKSVNHQGTDMRLCLDVFQDSQGCLELVSFKLRKEIVLLQKLQHPNIVELKGQCQDSILVGGITAVLEQGMPLQMIQLLQSPWEERFRVCLGLVRLLQYLSVSPLGSVALLDFQPRQFVMVSGELKLTDLDDASIHEPVCQEDSDCLLQFPLRNFTLRCSPAQTCKGLNEMRNLYNAYRYFFTYLLPHQAPPLLKPLIHHIMNATGDLKQSINETLIAFEKILHIYKSGLHLENLPTSITKDYAVLKGMRSVVNVEYRCWPSYRQQGCVLSVHSVREAAFICNSHTHCTSFSISSQTTWTGRLLASFRSGFSHLVPDVNSAVYMRRVKASGAVL", "length": 515, "header": "tr|A0A8M6Z1S2-1|A0A8M6Z1S2_DANRE Isoform 1 of Extracellular tyrosine-protein kinase PKDCC OS=Danio rerio OX=7955 GN=pkdccb PE=4 SV=2 CANONICAL=A0A8M6Z1S2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "dre:565254", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565254", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZP57-1", "protein_name": "Extracellular tyrosine-protein kinase PKDCC", "gene_name": "Pkdcc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRRRAAVAAGFCASFLLGSVLNVLFAPGSEPPRPGQSPGSSAAPGPGRRGGRGELARQIRERYEEVQRYSRGGPGPGAGRPERRRLMDLAPGGPGLQRPRPPRVRPPPDGAPGWPPAPGPGSPGPGPRLGCAALRNVSGAQYVGSGYTKAVYRVRLPGGAAVALKAVDFSGHDLGSCVREFGARRGCYRLAAHKLLKEMVLLERLRHPNVLQLYGYCYQDSEDIPDTLTTITELGAPVEMIQLLQTSWEDRFRICLSLGRLLHYLAHSPLGSVTLLDFRPRQFVLVDGELKVTDLDDARVEETPCTNGADCVLEFPARNFSLPCSAQGWCEGMNEKRNLYNAYRFFFTYLLPHSAPPSLRPLLDTIVNATGELAWGADETLAQLEMVLHLFRSGQYLQNSTSSRAEYQRIPDSTITQEDYRCWPSYHHGGCLLSVFNLAEAVDVCESHVQCRAFVVTNQTTWTGRKLVFFKTGWNQVVPDASKTTFVKAPG", "length": 492 }, "evidence": [ { "id": "MGI:2147077", "url": "https://alliancegenome.org/gene/MGI:2147077#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q504Y2-1", "protein_name": "Extracellular tyrosine-protein kinase PKDCC", "gene_name": "PKDCC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRRRAAVAAGFCASFLLGSVLNVLFAPGSEPPRPGQSPEPSPAPGPGRRGGRGELARQIRARYEEVQRYSRGGPGPGAGRPERRRLMDLAPGGPGLPRPRPPWARPLSDGAPGWPPAPGPGSPGPGPRLGCAALRNVSGAQYMGSGYTKAVYRVRLPGGAAVALKAVDFSGHDLGSCVREFGVRRGCYRLAAHKLLKEMVLLERLRHPNVLQLYGYCYQDSEDIPDTLTTITELGAPVEMIQLLQTSWEDRFRICLSLGRLLHHLAHSPLGSVTLLDFRPRQFVLVDGELKVTDLDDARVEETPCAGSTDCILEFPARNFTLPCSAQGWCEGMNEKRNLYNAYRFFFTYLLPHSAPPSLRPLLDSIVNATGELAWGVDETLAQLEKVLHLYRSGQYLQNSTASSSTEYQCIPDSTIPQEDYRCWPSYHHGSCLLSVFNLAEAVDVCESHAQCRAFVVTNQTTWTGRQLVFFKTGWSQVVPDPNKTTYVKASG", "length": 493 }, "evidence": [ { "id": "MGI:2147077", "url": "https://alliancegenome.org/gene/MGI:2147077#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5RJI4-1", "protein_name": "Extracellular tyrosine-protein kinase PKDCC", "gene_name": "Pkdcc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRRRAAVAAGFCASFLLGSVLNVLFAPGSEPPRPGQSPGSSAAPGPGRRGGRGELARQIRERYEEVQRYSRGGPGPGAGRPERRRLMDLAPGGPGLQRPRPPRVRSPPDGAPGWPPAPGPGSPGPGPRLGCAALRNVSGAQYVGSGYTKAVYRVRLPGGAAVALKAVDFSGHDLGSCVREFGARRGCYRLAAHKLLKEMVLLERLRHPNVLQLYGYCYQDSEGIPDTLTTITELGAPVEMIQLLQTSWEDRFRICLSLGRLLHHLAHSPLGSVTLLDFRPRQFVLVNGELKVTDLDDARVEETPCTSSADCTLEFPARNFSLPCSAQGWCEGMNEKRNLYNAYRFFFTYLLPHSAPPSLRPLLDSIVNATGELAWGVDETLAQLETALHLFRSGQYLQNSTSSRAEYQRIPDSAITQEDYRCWPSYHHGGCLLSVFNLAEAIDVCESHAQCRAFVVTNQTTWTGRKLVFFKTGWNQVVPDAGKTTYVKAPG", "length": 492 }, "evidence": [ { "id": "MGI:2147077", "url": "https://alliancegenome.org/gene/MGI:2147077#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-599", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-599#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1S2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1S2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1S2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1S2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1S2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ], "pmid": "" }, { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1S2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ], "pmid": "" }, { "name": "skeletal system development", "id": "GO:0001501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001501", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1S2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ], "pmid": "" }, { "name": "embryonic cranial skeleton morphogenesis", "id": "GO:0048701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048701", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1S2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ], "pmid": "" }, { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1S2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 394, "end_pos": 396, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10596", "name": "", "equation": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0ACD6B7V3-1", "A0A8M9PC12-1", "A1A5H8-1", "A2BIL7-1", "F1QVU0-1", "F1RDG9-1", "F8W3R9-1", "O12990-1", "O13146-1", "O13147-1", "O13148-1", "O73791-1", "O73792-1", "O73875-1", "O73878-1", "Q1JPZ3-1", "A0A8M1N4R3-1", "A0A8M9QKL5-1", "A0AC58HSB5-1", "F1QWX8-1", "F6P1M3-1", "A0A2R8Q7T0-1", "A0AC58HQU1-1", "Q9I8X3-1", "A0A8M1RHB8-1", "Q9YI66-1", "Q6EWH2-1", "Q8AXB3-1", "Q8AYG3-1", "Q8JFR5-1", "Q8JG38-1", "Q90413-1", "Q90Z00-1", "Q9DE49-1", "Q9DGE0-1", "Q9I8N6-1", "A0A8M2B201-1", "A0AC58HF58-1", "A0A8M2BD22-1", "A0A8M2BDJ7-1", "A0A8M1NUM7-1", "A0A8M3ASR9-1", "A0A8N7UW23-1", "Q4VSN1-1", "Q5GIT4-1", "Q5MD89-1", "A0A8M2B3P5-1", "A0A8M9Q7Y5-1", "B0V237-1", "B8A5K6-1", "A0A8M2B533-1", "A0A0R4IYB8-1", "A0A0R4J755-1", "E7F3X9-1", "Q1LX51-1", "Q1LYE1-1", "Q6DHU8-1", "A0A8M2B5G2-1", "A0A8M2BBT8-1", "E7FFT8-1", "A0A8M9QMM1-1", "F1QKJ0-1", "A0A8N7TED1-1", "A0AB32U1Z7-1", "A0A8M9Q613-1", "A0A8M6YUU4-1", "A0A8M6Z131-1", "E7FEW6-1", "F1QWE3-1", "X1WHM4-1", "A0A8N7T808-1", "E7F063-1", "A0A0R4ILA2-1", "A0A8M1PBN6-1", "A0A8M1NFV1-1", "A0AC58H751-1", "A0AB13A7B9-1", "A0A8N7UZ77-1", "A0AB40EDC8-1", "A0AB13A3P4-1", "A0AC58GDS8-1", "A0A8M3AX73-1", "A2CEJ3-1", "A0A8M9P2N6-1", "A0AB13A7P7-1", "E7F2W4-1", "E7F533-1", "F1QJD4-1", "A0A8M2B3B8-1", "A0AC58IDQ0-1", "A0A8M9PL45-1", "A0A8M6Z303-1", "A0A8M6Z1S2-1", "A0A8M1NB07-1", "A0AC58GTL4-1", "A0AC58H4I0-1", "A0AC58HW60-1", "A0AC58IMX1-1", "A0AC58JMV3-1", "A0AC58I1F4-1", "A0AC58IPF6-1", "A0AC58IS71-1", "A0AA53EB82-1", "A0AC58HYF2-1", "A0AC58JNM8-1" ], "evidence": [ { "id": "10596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10596" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A0R4ILA2", "gene_name": "ntrk2b", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0R4ILA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0R4ILA2" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A0R4ILA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0R4ILA2" } ] } ] }, { "uniprot_ac": "A0A0R4IYB8", "gene_name": "abl2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0R4IYB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IYB8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A0R4IYB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IYB8" } ] } ] }, { "uniprot_ac": "A0A0R4J755", "gene_name": "hck", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A0R4J755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J755" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A0R4J755", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A0R4J755" } ] } ] }, { "uniprot_ac": "A0A2R8Q7T0", "gene_name": "fes", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A2R8Q7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A2R8Q7T0" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A2R8Q7T0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A2R8Q7T0" } ] } ] }, { "uniprot_ac": "A0A8M1N4R3", "gene_name": "erbb3b", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M1N4R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N4R3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M1N4R3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N4R3" } ] } ] }, { "uniprot_ac": "A0A8M1NB07", "gene_name": "mtor", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M1NB07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NB07" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M1NB07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NB07" } ] } ] }, { "uniprot_ac": "A0A8M1NFV1", "gene_name": "tec", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M1NFV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NFV1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8M1NFV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NFV1" } ] } ] }, { "uniprot_ac": "A0A8M1NUM7", "gene_name": "fgfr1b", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M1NUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NUM7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M1NUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NUM7" } ] } ] }, { "uniprot_ac": "A0A8M1PBN6", "gene_name": "igf1rb", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M1PBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PBN6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M1PBN6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PBN6" } ] } ] }, { "uniprot_ac": "A0A8M1RHB8", "gene_name": "ntrk3b", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M1RHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1RHB8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M1RHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1RHB8" } ] } ] }, { "uniprot_ac": "A0A8M2B201", "gene_name": "syk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2B201", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B201" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8M2B201", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B201" } ] } ] }, { "uniprot_ac": "A0A8M2B3B8", "gene_name": "eif2ak3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2B3B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B3B8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M2B3B8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B3B8" } ] } ] }, { "uniprot_ac": "A0A8M2B3P5", "gene_name": "dyrk1ab", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2B3P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B3P5" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8M2B3P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B3P5" } ] } ] }, { "uniprot_ac": "A0A8M2B533", "gene_name": "dyrk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2B533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B533" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8M2B533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B533" } ] } ] }, { "uniprot_ac": "A0A8M2B5G2", "gene_name": "ptk2ba", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2B5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B5G2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8M2B5G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B5G2" } ] } ] }, { "uniprot_ac": "A0A8M2BBT8", "gene_name": "map2k4a", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2BBT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BBT8" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8M2BBT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BBT8" } ] } ] }, { "uniprot_ac": "A0A8M2BD22", "gene_name": "erbb3a", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2BD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BD22" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M2BD22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BD22" } ] } ] }, { "uniprot_ac": "A0A8M2BDJ7", "gene_name": "mst1ra", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2BDJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BDJ7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M2BDJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BDJ7" } ] } ] }, { "uniprot_ac": "A0A8M3ASR9", "gene_name": "fer", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3ASR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ASR9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8M3ASR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ASR9" } ] } ] }, { "uniprot_ac": "A0A8M3AX73", "gene_name": "csf1rb", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3AX73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AX73" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M3AX73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AX73" } ] } ] }, { "uniprot_ac": "A0A8M6YUU4", "gene_name": "blk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M6YUU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YUU4" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8M6YUU4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YUU4" } ] } ] }, { "uniprot_ac": "A0A8M6Z131", "gene_name": "ddr2b", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M6Z131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z131" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M6Z131", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z131" } ] } ] }, { "uniprot_ac": "A0A8M6Z1S2", "gene_name": "pkdccb", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M6Z1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8M6Z1S2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S2" } ] } ] }, { "uniprot_ac": "A0A8M6Z303", "gene_name": "ephb1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M6Z303", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z303" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M6Z303", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z303" } ] } ] }, { "uniprot_ac": "A0A8M9P2N6", "gene_name": "epha7", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9P2N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2N6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M9P2N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2N6" } ] } ] }, { "uniprot_ac": "A0A8M9PC12", "gene_name": "frk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PC12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC12" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8M9PC12", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC12" } ] } ] }, { "uniprot_ac": "A0A8M9PL45", "gene_name": "ephb2a", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PL45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL45" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M9PL45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL45" } ] } ] }, { "uniprot_ac": "A0A8M9Q613", "gene_name": "tesk1a", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q613" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0A8M9Q613", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q613" } ] } ] }, { "uniprot_ac": "A0A8M9Q7Y5", "gene_name": "si:ch73-383l1.1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q7Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M9Q7Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q7Y5" } ] } ] }, { "uniprot_ac": "A0A8M9QKL5", "gene_name": "pdgfrb", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9QKL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKL5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8M9QKL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKL5" } ] } ] }, { "uniprot_ac": "A0A8M9QMM1", "gene_name": "map2k4b", "activity": [ { "ec_number": "2.7.12.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9QMM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMM1" } ] }, { "ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8M9QMM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QMM1" } ] } ] }, { "uniprot_ac": "A0A8N7T808", "gene_name": "matk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8N7T808", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T808" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8N7T808", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T808" } ] } ] }, { "uniprot_ac": "A0A8N7TED1", "gene_name": "ptk6a", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8N7TED1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TED1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8N7TED1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TED1" } ] } ] }, { "uniprot_ac": "A0A8N7UW23", "gene_name": "btk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8N7UW23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW23" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8N7UW23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW23" } ] } ] }, { "uniprot_ac": "A0A8N7UZ77", "gene_name": "erbb4a", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8N7UZ77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ77" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0A8N7UZ77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ77" } ] } ] }, { "uniprot_ac": "A0AA53EB82", "gene_name": "epha6", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AA53EB82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AA53EB82" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AA53EB82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AA53EB82" } ] } ] }, { "uniprot_ac": "A0AB13A3P4", "gene_name": "ntrk2a", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB13A3P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A3P4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AB13A3P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A3P4" } ] } ] }, { "uniprot_ac": "A0AB13A7B9", "gene_name": "yrk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB13A7B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A7B9" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AB13A7B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A7B9" } ] } ] }, { "uniprot_ac": "A0AB13A7P7", "gene_name": "epha3", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB13A7P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A7P7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AB13A7P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A7P7" } ] } ] }, { "uniprot_ac": "A0AB32U1Z7", "gene_name": "erbb4b", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32U1Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32U1Z7" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AB32U1Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32U1Z7" } ] } ] }, { "uniprot_ac": "A0AB40EDC8", "gene_name": "dyrk3", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB40EDC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB40EDC8" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AB40EDC8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB40EDC8" } ] } ] }, { "uniprot_ac": "A0AC58GDS8", "gene_name": "insra", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58GDS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GDS8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AC58GDS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GDS8" } ] } ] }, { "uniprot_ac": "A0AC58GTL4", "gene_name": "mst1rb", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58GTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GTL4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AC58GTL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GTL4" } ] } ] }, { "uniprot_ac": "A0AC58H4I0", "gene_name": "epha4b", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58H4I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58H4I0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AC58H4I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58H4I0" } ] } ] }, { "uniprot_ac": "A0AC58H751", "gene_name": "itk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58H751", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58H751" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AC58H751", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58H751" } ] } ] }, { "uniprot_ac": "A0AC58HF58", "gene_name": "ptk2ab", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58HF58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HF58" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AC58HF58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HF58" } ] } ] }, { "uniprot_ac": "A0AC58HQU1", "gene_name": "ros1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58HQU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQU1" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AC58HQU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQU1" } ] } ] }, { "uniprot_ac": "A0AC58HSB5", "gene_name": "igf1ra", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58HSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HSB5" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AC58HSB5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HSB5" } ] } ] }, { "uniprot_ac": "A0AC58HW60", "gene_name": "cskl", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58HW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW60" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AC58HW60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW60" } ] } ] }, { "uniprot_ac": "A0AC58HYF2", "gene_name": "clk2a", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58HYF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HYF2" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0AC58HYF2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HYF2" } ] } ] }, { "uniprot_ac": "A0AC58I1F4", "gene_name": "LOC100329589", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58I1F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58I1F4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AC58I1F4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58I1F4" } ] } ] }, { "uniprot_ac": "A0AC58IDQ0", "gene_name": "ephb3b", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58IDQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58IDQ0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AC58IDQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58IDQ0" } ] } ] }, { "uniprot_ac": "A0AC58IMX1", "gene_name": "txk", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58IMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMX1" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AC58IMX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMX1" } ] } ] }, { "uniprot_ac": "A0AC58IPF6", "gene_name": "ek1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58IPF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58IPF6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AC58IPF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58IPF6" } ] } ] }, { "uniprot_ac": "A0AC58IS71", "gene_name": "LOC101884366", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58IS71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58IS71" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AC58IS71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58IS71" } ] } ] }, { "uniprot_ac": "A0AC58JMV3", "gene_name": "abl1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58JMV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58JMV3" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0AC58JMV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58JMV3" } ] } ] }, { "uniprot_ac": "A0AC58JNM8", "gene_name": "ddr2l", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58JNM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58JNM8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A0AC58JNM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58JNM8" } ] } ] }, { "uniprot_ac": "A0ACD6B7V3", "gene_name": "dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ACD6B7V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B7V3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0ACD6B7V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B7V3" } ] } ] }, { "uniprot_ac": "A1A5H8", "gene_name": "yes1", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A1A5H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5H8" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A1A5H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5H8" } ] } ] }, { "uniprot_ac": "A2BIL7", "gene_name": "baz1b", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2BIL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIL7" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A2BIL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIL7" } ] } ] }, { "uniprot_ac": "A2CEJ3", "gene_name": "ephb2b", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A2CEJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEJ3" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "A2CEJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEJ3" } ] } ] }, { "uniprot_ac": "B0V237", "gene_name": "jak3", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "B0V237", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "B0V237", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V237" } ] } ] }, { "uniprot_ac": "B8A5K6", "gene_name": "kitb", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "B8A5K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "B8A5K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5K6" } ] } ] }, { "uniprot_ac": "E7F063", "gene_name": "si:ch73-340m8.2", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F063" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "E7F063", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F063" } ] } ] }, { "uniprot_ac": "E7F2W4", "gene_name": "epha5", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F2W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2W4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E7F2W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2W4" } ] } ] }, { "uniprot_ac": "E7F3X9", "gene_name": "ddr1", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F3X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F3X9" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E7F3X9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F3X9" } ] } ] }, { "uniprot_ac": "E7F533", "gene_name": "epha2b", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F533" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E7F533", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F533" } ] } ] }, { "uniprot_ac": "E7FEW6", "gene_name": "tesk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7FEW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FEW6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E7FEW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FEW6" } ] } ] }, { "uniprot_ac": "E7FFT8", "gene_name": "ddr2a", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7FFT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FFT8" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "E7FFT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FFT8" } ] } ] }, { "uniprot_ac": "F1QJD4", "gene_name": "epha4l", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1QJD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QJD4" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1QJD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QJD4" } ] } ] }, { "uniprot_ac": "F1QKJ0", "gene_name": "ntrk3a", "activity": [ { "ec_number": "2.7.10.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1QKJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QKJ0" } ] }, { "ec_number": "2.7.10.1", "activity": "", "evidence": [ { "id": "F1QKJ0", "database": "UniProtKB", "url": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z1T3-1", "uniprot_ac": "A0A8M6Z1T3", "uniprot_id": "A0A8M6Z1T3_DANRE", "mass": { "chemical_mass": 80305.0, "monoisotopic_mass": 80305.0 }, "refseq": { "ac": "XP_017207337", "name": "calpain-1 catalytic subunit", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207337" }, "gene_names": [ { "name": "si:ch211-202f3.3", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3" } ] }, { "name": "si:ch211-202f3.3", "type": "synonym", "evidence": [ { "id": "XP_017207337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207337" } ] } ], "protein_names": [ { "name": "Calpain-1 catalytic subunit", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3/entry#names_and_taxonomy" } ] }, { "name": "calpain-1 catalytic subunit", "type": "synonym", "evidence": [ { "id": "XP_017207337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207337" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017207337.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017207337", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207337" } ] } ], "disease": [ { "disease_id": "DOID:11723", "recommended_name": { "id": "DOID:11723", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11723", "name": "Duchenne muscular dystrophy", "description": "A muscular dystrophy that has_material_basis_in X-linked mutations in the DMD gene found on the X chromosome. It is characterized by rapidly progressing muscle weakness and muscle atrophy initially involving the lower extremities and eventually affecting the whole body. It affects males whereas females can be carriers. The symptoms start before the age of six and may appear at infancy." }, "synonyms": [ { "id": "DOID:11723", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11723", "name": "Muscular dystrophy, Duchenne", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "Duchenne muscular dystrophy", "description": "Duchenne muscular dystrophy (DMD) is a neuromuscular disease characterized by rapidly progressive muscle weakness and wasting due to degeneration of skeletal, smooth and cardiac muscle." }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "DMD", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "Duchenne muscular dystrophy", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "Duchenne muscular dystrophy, X-linked recessive", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "severe dystrophinopathy, Duchenne type", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "muscular dystrophy, Duchenne type", "description": "" }, { "id": "MIM:310200", "resource": "MIM", "url": "https://www.omim.org/entry/310200", "name": "Duchenne muscular dystrophy", "description": "Duchenne muscular dystrophy" } ], "unlinked_id_list": [], "evidence": [ { "id": "11723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11723" } ] }, { "disease_id": "DOID:13922", "recommended_name": { "id": "DOID:13922", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13922", "name": "eosinophilic esophagitis", "description": "An esophagitis characterized by inflammation involving eosinophils located_in esophagus." }, "synonyms": [ { "id": "MONDO:0012451", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012451", "name": "esophagitis, eosinophilic, 1", "description": "" }, { "id": "MONDO:0012451", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012451", "name": "EOE1", "description": "" }, { "id": "MONDO:0012451", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012451", "name": "esophagitis, eosinophilic, 1", "description": "" }, { "id": "MONDO:0013260", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013260", "name": "esophagitis, eosinophilic, 2", "description": "" }, { "id": "MONDO:0013260", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013260", "name": "EOE2", "description": "" }, { "id": "MONDO:0013260", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013260", "name": "esophagitis, eosinophilic, 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13922", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13922" } ] }, { "disease_id": "DOID:2476", "recommended_name": { "id": "DOID:2476", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2476", "name": "hereditary spastic paraplegia", "description": "A paraplegia that is characterized by progressive stiffness and contraction (spasticity) in the lower limbs." }, "synonyms": [ { "id": "DOID:2476", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2476", "name": "French settlement disease", "description": "" }, { "id": "DOID:2476", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2476", "name": "Strumpell-Lorrain disease", "description": "" }, { "id": "DOID:2476", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2476", "name": "familial spastic paraplegia", "description": "" }, { "id": "DOID:2476", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2476", "name": "hereditary spastic paraparesis", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "MASA syndrome", "description": "MASA syndrome (Mental retardation, Aphasia, Spastic paraplegia, Adducted thumbs) is a historical term used to describe a phenotype now considered to be part of the X-linked L1 clinical spectrum (L1 syndrome). MASA is characterized by mild to moderate intellectual deficit, delayed development of speech, hypotonia progressing to spasticity or spastic paraplegia, adducted thumbs, and mild to moderate distension of the cerebral ventricles." }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "Gareis-Mason syndrome", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "MASA syndrome", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "intellectual disability-aphasia-shuffling gait-adducted thumbs syndrome", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "masa syndrome, X-linked recessive", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "spastic paraplegia, X-linked", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "Clasped thumb and mental retardation", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "adducted thumb with mental retardation", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "intellectual disability aphasia shuffling Gait adducted thumbs (MASA)", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "mental retardation aphasia shuffling Gait adducted thumbs (MASA)", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "mental retardation, aphasia, shuffling Gait, and adducted thumbs", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "spastic paraplegia 1", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "thumb congenital clasped with intellectual disability", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "thumb congenital clasped with mental retardation", "description": "" }, { "id": "MONDO:0010559", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010559", "name": "thumb, congenital Clasped, with mental retardation", "description": "" }, { "id": "MIM:303350", "resource": "MIM", "url": "https://www.omim.org/entry/303350", "name": "MASA syndrome", "description": "MASA syndrome" } ], "unlinked_id_list": [ "DOID:0110771" ], "evidence": [ { "id": "2476", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2476" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-202f3.3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080917-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080917-19", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z1T3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z1T3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00044", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00044", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00214", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00214", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16195", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16195", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "553353", "url": "https://www.ncbi.nlm.nih.gov/gene/553353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022682", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022682", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022683", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022683", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:553353", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1T3", "url": "https://www.orthodb.org/?gene=A0A8M6Z1T3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10183:SF302", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10183:SF302", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21875", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21875", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017207337", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207337", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080917-19", "url": "https://zfin.org/ZDB-GENE-080917-19", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPPPVVPHGMCLKVMNDRNMKGGMGSDTNPLKFMDQDYNFLQDYCLKTRQRFVDEFFPPDLRSIGEGLLKPEVMARVEWIRPTKLYPEAAEFVVDTVSRFDYAQGFIGNCWFLASVGALTFQSKLLQKVVPDGQSLRHNYTGLFHFRFWRFGKWFDVVIDDKLPTINRQLIFVKSKTYNEFWPALLEKAYAKVCGSYADMHTGRVSEALLDFTGGVHMHYDLKTAPTDLWEIMYRASQSEVLMGCESPAGNEERLPNGIVLGHAYTVTKVYQVMSGRNPVQLVRLFNPWGDSEWNGDWSDNSPLWNTVDDEDRKQLLVSDNGEFWMSMKDFLRTFDNMDICCNCPDFLEGKSACKWTSKSHNGSWVPGSTAGGCMNHPDTFCTNPQFWLRINEMDKTCDQGQNNVLVSLIQKPDKRNRRLAQHHGIGFCVFAVPPEMRSEGKFRSSFFNRKPVVTSGNFQDARQVMKFFRLEPGEYLIVPSTYLPNKNADFILSILCKNDIQIQKDTERTEKDFLVDLIGVSESGCTEKEDEESKTKFLFRQYSDQYKVVDAEKLQQILHENLLRGRKNAEGFGLDSCRSMIAMSDFCVTGRLQGSEFVRLWDRITTYRDIFYNMDSSKDGVLSLNELQNALEKTGLHLNEDILNLMVVRYGGASEQISLEGFICLVMRLNCMASIFQKLCENGKISLDESEWIGLTMYS", "length": 700, "header": "tr|A0A8M6Z1T3-1|A0A8M6Z1T3_DANRE Isoform 1 of Calpain-1 catalytic subunit OS=Danio rerio OX=7955 GN=si:ch211-202f3.3 PE=3 SV=2 CANONICAL=A0A8M6Z1T3-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3/entry#A0A8M6Z1T3-1", "sequence": { "sequence": "MPPPVVPHGMCLKVMNDRNMKGGMGSDTNPLKFMDQDYNFLQDYCLKTRQRFVDEFFPPDLRSIGEGLLKPEVMARVEWIRPTKLYPEAAEFVVDTVSRFDYAQGFIGNCWFLASVGALTFQSKLLQKVVPDGQSLRHNYTGLFHFRFWRFGKWFDVVIDDKLPTINRQLIFVKSKTYNEFWPALLEKAYAKVCGSYADMHTGRVSEALLDFTGGVHMHYDLKTAPTDLWEIMYRASQSEVLMGCESPAGNEERLPNGIVLGHAYTVTKVYQVMSGRNPVQLVRLFNPWGDSEWNGDWSDNSPLWNTVDDEDRKQLLVSDNGEFWMSMKDFLRTFDNMDICCNCPDFLEGKSACKWTSKSHNGSWVPGSTAGGCMNHPDTFCTNPQFWLRINEMDKTCDQGQNNVLVSLIQKPDKRNRRLAQHHGIGFCVFAVPPEMRSEGKFRSSFFNRKPVVTSGNFQDARQVMKFFRLEPGEYLIVPSTYLPNKNADFILSILCKNDIQIQKDTERTEKDFLVDLIGVSESGCTEKEDEESKTKFLFRQYSDQYKVVDAEKLQQILHENLLRGRKNAEGFGLDSCRSMIAMSDFCVTGRLQGSEFVRLWDRITTYRDIFYNMDSSKDGVLSLNELQNALEKTGLHLNEDILNLMVVRYGGASEQISLEGFICLVMRLNCMASIFQKLCENGKISLDESEWIGLTMYS", "length": 700, "header": "tr|A0A8M6Z1T3-1|A0A8M6Z1T3_DANRE Isoform 1 of Calpain-1 catalytic subunit OS=Danio rerio OX=7955 GN=si:ch211-202f3.3 PE=3 SV=2 CANONICAL=A0A8M6Z1T3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:553353", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553353", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB40ECQ1-1", "protein_name": "Calpain-2 catalytic subunit", "gene_name": "si:ch211-202f3.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPPPNNCHHNPNEDEVDSLTSPLYFLDQNYQELQQKCLTESTLYSDELFPPDNSSIGLFDEVPPEVDMSQIVWKRPSELVSDPNLIVDDVSRFDYAQGSVLGNCWFLASIGALTFEKDIMKQVLPAEQSFTKDYAGIFHFRFWRFEKWIDVVIDDQLPTIDDELLFVCSKTSNEFWPALLEKAYAKVCGSYADLNAGFISEALMDFTGGTHMYYTLSSAPADLWKIMECAFISKTLIGCGSNSEGSPEENELLHGIIADHAYTVTGVFEVISEENPVQLVRLLNPWGEEEWQGDWSDESPLWETVCEEARKCCREVLNDGEFWMSMEDFTRLFESIDICCLCPDFLDGSSDCHWTSKRHFGRWNAEKFMYNTFIHHLTAGGDIIKTETFWKNPQFRVTIDELNEDCASGQRPENILVSLMQNHEKRNRNSQENYDIGFYVFEMRHQNERFAMEFFADREPVAHTDDLVWLREVMKFFRLEPGEYLIVPCTKNPGETASFVLSVFSKHETHLEQIQETTE", "length": 519 }, "evidence": [ { "id": "HGNC:16664", "url": "https://alliancegenome.org/gene/HGNC:16664#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A8MX76-1", "protein_name": "Calpain-14", "gene_name": "CAPN14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLWPPFRCRWKLAPRYSRRASPQQPQQDFEALLAECLRNGCLFEDTSFPATLSSIGSGSLLQKLPPRLQWKRPPELHSNPQFYFAKAKRLDLCQGIVGDCWFLAALQALALHQDILSRVVPLNQSFTEKYAGIFRFWFWHYGNWVPVVIDDRLPVNEAGQLVFVSSTYKNLFWGALLEKAYAKLSGSYEDLQSGQVSEALVDFTGGVTMTINLAEAHGNLWDILIEATYNRTLIGCQTHSGEKILENGLVEGHAYTLTGIRKVTCKHRPEYLVKLRNPWGKVEWKGDWSDSSSKWELLSPKEKILLLRKDNDGEFWMTLQDFKTHFVLLVICKLTPGLLSQEAAQKWTYTMREGRWEKRSTAGGQRQLLQDTFWKNPQFLLSVWRPEEGRRSLRPCSVLVSLLQKPRHRCRKRKPLLAIGFYLYRMNKYHDDQRRLPPEFFQRNTPLSQPDRFLKEKEVSQELCLEPGTYLIVPCILEAHQKSEFVLRVFSRKHIFYEIGSNSGVVFSKEIEDQNERQDEFFTKFFEKHPEINAVQLQNLLNQMTWSSLGSRQPFFSLEACQGILALLDLNASGTMSIQEFRDLWKQLKLSQKVFHKQDRGSGYLNWEQLHAAMREAGIMLSDDVCQLMLIRYGGPRLQMDFVSFIHLMLRVENMEDVFQNLTQDGKGIYLQKPEWMMMALYS", "length": 684 }, "evidence": [ { "id": "HGNC:16664", "url": "https://alliancegenome.org/gene/HGNC:16664#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080917-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080917-19#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UW68-1", "protein_name": "Calpain-13", "gene_name": "Capn13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAHDAETSVVKFKNQDFRTLRDHCLSRGQLFIDDTFPAAASSIGEKLLRGKHLSKLEWKRPTSKDLPFYPPHFILEGASRFDIHQGIAGDCWFLAALGSLTQNPQCLQKILMDQSYSHQYAGIFQFRFWQCGQWVEVVIDDQLPVIGDNFLFVHPRGGNKEFWPCLMEKAYAKLLGSYSQLHYGYLPDALVDLTGGVVTIINLHSSPFDLLTTVKTAIQAGSMVACATENGLTEEAKVMENGLVSQHAYTVTGAEKIQYQGRWEDIIRLWNPWGKTEWKGRWKDGSKEWRETHDPRKSQLYENKEDGEFWMSCQDFQENFSCLFICNQIPITMDHGVTPNESWRQMRFTNQVISRNRAGGHGRDMQYVFSVQEHTAGNNVVVAFTIMPQSLNTEEERFPLQFQVFKVPQFQNVQGRLPPAFFSPFRSAAQGTKYVSKCNFTKSFHLNPGTYVVVTTANGKEVEFLLRIFLKMPDKHRDPSSNFNLRALKESLPENGSRNSISYTYMDQGLDIDATQLQSLLNQEFLTGPPGDTFSLDQCQSIMALMDLKVNGRLDQEEFARLRSRLIHCQHIFQSIQRRPGVLLSSDLWKVIENTDFLVGIFISSELLSLMALRYSDSSGRVSFPTLVCFLIRLETMAKAFRNLSKDGKGIYLTETEWMNLVMYS", "length": 665 }, "evidence": [ { "id": "RGD:1562682", "url": "https://alliancegenome.org/gene/RGD:1562682#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5BK10-1", "protein_name": "Calpain-13", "gene_name": "Capn13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHDTEALEETSVVKFKNQDFRFLRDRCLSRGQLFIDDTFPAEASSIGQKLLMGKRLPKLEWKRPQDLSFGPPHFILEGASRFDIQQGRAGDCWFLAALGSLTQNPQCLQKILMNQSFSYQYAGIFHFRFWQCGQWVEVVIDDRLPVVGNNFCFVHPRRGNQEFWPCLMEKAYAKLLGSYSQLHYGYLPDALVDLTGGVVTRINLHSSPSDLLMVVKTAVQTGSMVACATPKWLTEESEVMENGLVSQHAYTVTGAEKIQYRRGWEEIIRLWNPWGNTEWRGRWGDGSQEWWETHGSRKSQLYENKDDGEFWMSCRDFHENFSCLYICSQFPITMDPGVTPNESWRQMRFKNQVISGNTAGGDGRDIQYLFDVQEPMDGNNVIVAFTVMPQSLKTEEWPFPLQFQVFKVDSQFQKFQKRLPPAFFSQFRDAAQGIDYVTKRNFTKSFHLSPGTYVVVASAHGKEVEFLLRIFLKMPHKDRNPNSSFNLKALKGSLSENESPKSSFHRYMDQGLDIDASQLQSLLNQEYLTGPPGDTFSLDQCQSIMALMDLKVNGRLDREEFARLQSRLIHCQHVFQHIQRSQGVLRSSDLWEVIESTDFLSGVLLSKELLSLMTLRYSDSSGRLSFPSLVCFLIRLETMSKAFRNLSKDGKSIYLTEMEWMKLVMYS", "length": 668 }, "evidence": [ { "id": "RGD:1562682", "url": "https://alliancegenome.org/gene/RGD:1562682#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080917-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080917-19#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6MZZ7-1", "protein_name": "Calpain-13", "gene_name": "CAPN13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAYYQEPSVETSIIKFKDQDFTTLRDHCLSMGRTFKDETFPAADSSIGQKLLQEKRLSNVIWKRPQDLPGGPPHFILDDISRFDIQQGGAADCWFLAALGSLTQNPQYRQKILMVQSFSHQYAGIFRFRFWQCGQWVEVVIDDRLPVQGDKCLFVRPRHQNQEFWPCLLEKAYAKLLGSYSDLHYGFLEDALVDLTGGVITNIHLHSSPVDLVKAVKTATKAGSLITCATPSGPTDTAQAMENGLVSLHAYTVTGAEQIQYRRGWEEIISLWNPWGWGEAEWRGRWSDGSQEWEETCDPRKSQLHKKREDGEFWMSCQDFQQKFIAMFICSEIPITLDHGNTLHEGWSQIMFRKQVILGNTAGGPRNDAQFNFSVQEPMEGTNVVVCVTVAVTPSNLKAEDAKFPLDFQVILAGSQRFREKFPPVFFSSFRNTVQSSNNKFRRNFTMTYHLSPGNYVVVAQTRRKSAEFLLRIFLKMPDSDRHLSSHFNLRMKGSPSEHGSQQSIFNRYAQQRLDIDATQLQGLLNQELLTGPPGDMFSLDECRSLVALMELKVNGRLDQEEFARLWKRLVHYQHVFQKVQTSPGVLLSSDLWKAIENTDFLRGIFISRELLHLVTLRYSDSVGRVSFPSLVCFLMRLEAMAKTFRNLSKDGKGLYLTEMEWMSLVMYN", "length": 669 }, "evidence": [ { "id": "RGD:1562682", "url": "https://alliancegenome.org/gene/RGD:1562682#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium-dependent cysteine-type endopeptidase activity", "id": "GO:0004198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004198", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1T3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 362, "end_pos": 364, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z1T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3" }, { "id": "PS50203", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50203" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Calpain catalytic", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 341, "start_aa": "Arg", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z1T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1T3" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 603, "end_pos": 638, "start_aa": "Asp", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 362, "end_pos": 364 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z1W1-1", "uniprot_ac": "A0A8M6Z1W1", "uniprot_id": "A0A8M6Z1W1_DANRE", "mass": { "chemical_mass": 40874.0, "monoisotopic_mass": 40874.0 }, "refseq": { "ac": "XP_017206899", "name": "free fatty acid receptor 3 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206899" }, "gene_names": [ { "name": "LOC100004033", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1W1" } ] }, { "name": "LOC100004033", "type": "synonym", "evidence": [ { "id": "XP_017206899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206899" } ] } ], "protein_names": [ { "name": "Free fatty acid receptor 3 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1W1/entry#names_and_taxonomy" } ] }, { "name": "free fatty acid receptor 3 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_017206899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206899" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017206899.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017206899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206899" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1W1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1W1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100004033", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1W1", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z1W1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z1W1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100004033", "url": "https://www.ncbi.nlm.nih.gov/gene/100004033", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100004033", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004033", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1W1", "url": "https://www.orthodb.org/?gene=A0A8M6Z1W1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45822", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45822", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45822:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45822:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017206899", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206899", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1W1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLL3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLL3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLL3-1", "database": "UniProtKB", 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"MRRATGQTGNSGKAIHTEVFLQWTVWNSAAMQACDYYLCLSVYLITFITGFPANIFAFYTLIRKIWRKPAPIDILLLNLTISDLLFLIFLPFKMQEVVNNMQWNIDYFLCPLSGFIFYMTIYNSAFFLTAVSVERYLGVAFPIQHSLRRRPIYAVFASIFMWVFSTLHLSIVYIVPYYNPSGTIPPSRNVCYEGFTEAQLEILLPVRLELFIVLFCVPLLICSFCYINFIRILSRLPNIGRRRRLRAIGLALGTLLVFALCFGPYNVSHVVGFITKESPDWRDKTLLLSTFNACLDPFIFYFTSAAVRSTFSGMIRGIWGRCWCPQILWSSKKEQQEMEKNSLPKPQDVTNAL", "length": 353, "header": "tr|A0AC58HLN6-1|A0AC58HLN6_DANRE Computationally mapped isoform of Free fatty acid receptor 3 isoform X1 OS=Danio rerio OX=7955 GN=LOC100004033 PE=4 SV=1 CANONICAL=A0A8M6Z1W1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100004033", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004033", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": 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"id": "A0A8M6Z1W1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1W1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z1W1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1W1" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 300, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 266, "end_pos": 268 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z1Y6-1", "uniprot_ac": "A0A8M6Z1Y6", "uniprot_id": "A0A8M6Z1Y6_DANRE", "mass": { "chemical_mass": 35063.0, "monoisotopic_mass": 35063.0 }, "refseq": { "ac": "XP_017212664", "name": "thyroid hormone receptor interactor 10b isoform X4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212664" }, "gene_names": [ { "name": "zmp:0000001172", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Y6" } ] }, { "name": "trip10b", "type": "synonym", "evidence": [ { "id": "XP_017212664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212664" }, { "id": "A0A8M6Z1Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Y6" } ] }, { "name": "zgc:56292", "type": "synonym", "evidence": [ { "id": "XP_017212664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212664" }, { "id": "A0A8M6Z1Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Y6" } ] } ], "protein_names": [ { "name": "Thyroid hormone receptor interactor 10b isoform X4", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1Y6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Y6/entry#names_and_taxonomy" } ] }, { "name": "thyroid hormone receptor interactor 10b isoform X4", "type": "synonym", "evidence": [ { "id": "XP_017212664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212664" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017212664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212664" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1Y6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Y6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zmp:0000001172", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Y6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-140106-132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-132", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z1Y6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z1Y6", "database": "AlphaFoldDB", "categories": [] }, { "id": "108179043", "url": "https://www.ncbi.nlm.nih.gov/gene/108179043", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "A0A8M6Z1Y6", "url": "https://www.orthodb.org/?gene=A0A8M6Z1Y6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38706", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38706", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38706:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38706:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_017212664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212664", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1Y6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-140106-132", "url": "https://zfin.org/ZDB-GENE-140106-132", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLATLNEVPHLRNTGFGRPWPRHGLKLLHWFAKECLIFDNNNNMRTDYYPADGDFGFHLFENRCDEYGDKLLPDVNFPYYVVGNLNSAGAENLPEYVTEYKCTDEDYSNTDRIIVSLHDDCEFDKVYITQHKDRSNYDPYNTHRISKGLLMIIRRIRLEDFLEGMCYYPYMQPVSPMPIINYRPIATNTAGPGFIVVNYPHVQPISLIPNIPENPGFVKVNYPYSQPISLKSVRKCRPKSTNTVSPDLTAVTVPSSHPPHHDAPAAQSSGTNAETIITIEEETSTNNPSENSPKKKRFWERLCTIL", "length": 306, "header": "tr|A0A8M6Z1Y6-1|A0A8M6Z1Y6_DANRE Isoform 1 of Thyroid hormone receptor interactor 10b isoform X4 OS=Danio rerio OX=7955 GN=zmp:0000001172 PE=4 SV=1 CANONICAL=A0A8M6Z1Y6-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Y6/entry#A0A8M6Z1Y6-1", "sequence": { "sequence": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z1Z6-1", "uniprot_ac": "A0A8M6Z1Z6", "uniprot_id": "A0A8M6Z1Z6_DANRE", "mass": { "chemical_mass": 27436.0, "monoisotopic_mass": 27436.0 }, "refseq": { "ac": "XP_001339903", "name": "microfibril-associated glycoprotein 4-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339903" }, "gene_names": [ { "name": "mfap4.3", "type": "recommended", "evidence": [ { "id": "A0A8M6Z1Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6" } ] }, { "name": "mfap4.3", "type": "synonym", "evidence": [ { "id": "XP_001339903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339903" } ] } ], "protein_names": [ { "name": "Microfibril-associated glycoprotein 4-like isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z1Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6/entry#names_and_taxonomy" } ] }, { "name": "microfibril-associated glycoprotein 4-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001339903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339903" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001339903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339903" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mfap4.3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110408-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-14", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00087", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00087", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100007474", "url": "https://www.ncbi.nlm.nih.gov/gene/100007474", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037579", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037579", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100007474", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100007474", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1Z6", "url": "https://www.orthodb.org/?gene=A0A8M6Z1Z6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47221", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47221", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47221:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47221:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47221:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47221:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001339903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339903", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G5I7", "url": "https://www.uniprot.org/uniprotkb/A0AC58G5I7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G5I7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G5I7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110408-14", "url": "https://zfin.org/ZDB-GENE-110408-14", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAIVLFLATLLSAALASDCTSMPFDCSDIYKSGETLSGVYTIYPAGETPVWVYCQMLSDGKDEENGGWTVIQRRMDGSVNFYRPWRDYKRGFGNVEGEYWLGLENLYQLTRHKKFMLRVDLEDFEGRRGFAQYSSFSVGCECEGYKLQVSGFTDGGAGDSLSPHNGMKFSTFDKDQDTYEKNCAKEFLGGFWYSSCHNTNPNAVYLWEEDVTHHAIGVSWYSWKGTHAVSMKTISMKIKQVP", "length": 242, "header": "tr|A0A8M6Z1Z6-1|A0A8M6Z1Z6_DANRE Isoform 1 of Microfibril-associated glycoprotein 4-like isoform X1 OS=Danio rerio OX=7955 GN=mfap4.3 PE=4 SV=1 CANONICAL=A0A8M6Z1Z6-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6/entry#A0A8M6Z1Z6-1", "sequence": { "sequence": "MAIVLFLATLLSAALASDCTSMPFDCSDIYKSGETLSGVYTIYPAGETPVWVYCQMLSDGKDEENGGWTVIQRRMDGSVNFYRPWRDYKRGFGNVEGEYWLGLENLYQLTRHKKFMLRVDLEDFEGRRGFAQYSSFSVGCECEGYKLQVSGFTDGGAGDSLSPHNGMKFSTFDKDQDTYEKNCAKEFLGGFWYSSCHNTNPNAVYLWEEDVTHHAIGVSWYSWKGTHAVSMKTISMKIKQVP", "length": 242, "header": "tr|A0A8M6Z1Z6-1|A0A8M6Z1Z6_DANRE Isoform 1 of Microfibril-associated glycoprotein 4-like isoform X1 OS=Danio rerio OX=7955 GN=mfap4.3 PE=4 SV=1 CANONICAL=A0A8M6Z1Z6-1" }, "locus": {} }, { "isoform_ac": "A0AC58G5I7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6/entry#A0AC58G5I7-1", "sequence": { "sequence": "MAIVLFLATLLSAALASDCTSMPFDCSDIYKSGETLSGVYTIYPAGETPVWVYCQMLSDGKDEENGGWTVIQRRMDGSVNFYRPWRDYKRGFGNVEGEYWLGLENLYQLTRHKKFMLRVDLEDFEGRRGFAQYSSFSVGCECEGYKLQVSGFTDGGAVLHL", "length": 161, "header": "tr|A0AC58G5I7-1|A0AC58G5I7_DANRE Computationally mapped isoform of Microfibril-associated glycoprotein 4-like isoform X2 OS=Danio rerio OX=7955 GN=mfap4.3 PE=4 SV=1 CANONICAL=A0A8M6Z1Z6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100007474", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100007474", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4K7T3-1", "protein_name": "Fibrinogen C-terminal domain-containing protein", "gene_name": "AAF57948", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKPICFALCVFSLGLFYLASAEIGENVKIQTYKKYSSSCKELNPKKSGVQKIQVGSDVIEVYCDVTIAGKGWLVVQRRVSVEENFYRNWTSYQTGFGDLKGNFFIGLNNLNKISSLQPQELYIELVDFAGEKRYAHYSVFHVGNVYSNYPITQLGAYSGTAGDSLSYHLYQPFSTFDRDNDNATINCAARYMGAWWYRECLSRIPCSNLNGAYLGGNHTDPALFGSGIVWGEWKGFTYSYKTVNIMVRPK", "length": 250 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-14#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" }, { "id": "RGD:1307841", "url": "https://alliancegenome.org/gene/RGD:1307841#orthology", "database": "AGR" }, { "id": "FB:FBgn0034160", "url": "https://alliancegenome.org/gene/FB:FBgn0034160#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8M1PI90-1", "protein_name": "Microfibril-associated glycoprotein 4 isoform X1", "gene_name": "mfap4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAIVLFLATLLSAALASDCTSMPFDCSDIYKSGETLSGVYTIYPAGETPVWVYCQMLSDGKDEENGGWTVIQRRMDGSVNFYRPWRDYKRGFGNVEGEYWLGLENLYQLTRHKKFMLRVDLEDFEGRRGFAQYSSFSVGCECEGYKLQVSGFTDGGAGDSLSGHNGVKFSTFDKDQDTYDKNCAKEFLGAFWYGSCHTTNPNAVYLWGEDATHHAIGVCWYTWKGTHTVSMKIISMKIKQMP", "length": 242 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" }, { "id": "RGD:1307841", "url": "https://alliancegenome.org/gene/RGD:1307841#orthology", "database": "AGR" }, { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" }, { "id": "FB:FBgn0034160", "url": "https://alliancegenome.org/gene/FB:FBgn0034160#orthology", "database": "AGR" }, { "id": "FB:FBgn0033312", "url": "https://alliancegenome.org/gene/FB:FBgn0033312#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB12YYE4-1", "protein_name": "Uncharacterized protein LOC100126131 precursor", "gene_name": "mfap4.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALIWILAALLSAALASDCRFMQFDCSDIYNSGETLSGAYTIYPAGDSPVWVYCQMVSEGKDEDNGGWTVIQRRMDGSVNFYRPWRDYKRGFGNVEGEYWLGLENLYQLTRHKKFMLRVDLEDFEGRRGFAQYSSFSVGCECEGYKLQVSGFTDGGAGDSMTPHNEMKFSTFDKDQDTYEKNCAKEYLGAFWYGYCHNTNPNGVYLWEDDSTHFAIGVTWYSWKNTHDMSLKYISMKIKHLS", "length": 242 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" }, { "id": "RGD:1307841", "url": "https://alliancegenome.org/gene/RGD:1307841#orthology", "database": "AGR" }, { "id": "FB:FBgn0034160", "url": "https://alliancegenome.org/gene/FB:FBgn0034160#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z7G6-1", "protein_name": "Fibrinogen C-terminal domain-containing protein", "gene_name": "AAF59068", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEYYSIILILIMLPSAWCLQVPSKIKSTTKAPVKEIPPTNGTQIGNVTAVAPVPEKLAEVHIDQHKTIRISKGDLDDLLDVYMGKIAESAATIKDKENEINKLQTKDQTGDELLRKFENLTQVCSAQQSSFTTAIKEKDEQIKELEQKVKVYETRLKRKQHVLAELRKLNGSSALLIEHLKGKVVYFERKFREKKDDLLADWEAATTSCVPFGRSPGIHLIHLPGFLPFLVPCEGQTAAGPGWTCIQRRLDGSVNFYRNWDAYSKGFGKLNGEFFIGLEKLHRLTSSQPHELYISIRRFGGETSYAHYDDFLIGSEEEGYELKLLGHYQGNASDALRTHDKMKFSTYDRDNDAFTHMNCAEHHQGAWWYDFCSRSNLNGRYFKGEVDNPQSIYWEPWYSFRSLKSVQMLIRPKSQLELKDLPRPMRPPG", "length": 429 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-14#orthology", "database": "AGR" }, { "id": "RGD:1307841", "url": "https://alliancegenome.org/gene/RGD:1307841#orthology", "database": "AGR" }, { "id": "FB:FBgn0033312", "url": "https://alliancegenome.org/gene/FB:FBgn0033312#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A2AV25-1", "protein_name": "Fibrinogen C domain-containing protein 1", "gene_name": "Fibcd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVHERWKTVGSASQLEDRPRDKPQRASCSYVLCTVLLSLAVLLAVAVTGVVLFLNHTHTPGTAPPPIVSTGTAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRALSEHQAQPRLDGAPELLDALADQLPRLLTRASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSIFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 459 }, "evidence": [ { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5PMA3-1", "protein_name": "Fibrinogen C domain-containing protein 1", "gene_name": "fibcd1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLNDRWGIMNSSPELEDGQRGKNQRMSCSYLLCTILLFVAVLLAVTVTGTILLMNHYQAPPMSDGPPHISTNQDEANALVTVERGDGSRINIFIDPNCPDYNSNFLRLEGVQTSLLHSLTDHDTDLKSVKGQDRALLVNLAEEVAKLSAHAGQLKMDYESLRRGQSNLGQDLNTLQTEQSRLIQLLSESQINMVKVVNSVSDALNAMQKETGGLKARVKADLQRAPVRGVRLKGCANGSRPRDCSDIYASGQREDGIYSVFPTHYPAGFQVYCDMSTDGGGWTRREDGSVNFFREWDSYREGFGKITGEYWLGLKQIHALSIQGNYELRIDLEDFENSTAFAQYGVFGVGLFSVDPEDDGYPLTIADYTGTAGDSLLKHNGMKFTTKDRDNDHSENNCASFYHGAWWYRNCHTSNLNGQYLRGQHTSYADGIEWSSWTGWQYSLKFTEMKIRPTRDERETK", "length": 461 }, "evidence": [ { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4ADA1-1", "protein_name": "Fibrinogen C domain containing 1", "gene_name": "Fibcd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVHERWKTVGGASQLEDRPRDKPQRAGCSYILCTVLLSLAVLLAVAVTGAVLFLNHAHAPGTAPPPIVSTGAAGANSALVTVERADSSHLSLLIDPRCPDLTDSFARLEGIQASILRTLSEHQAQPRLDGAPELLDALADQLPRLLARASELQAECAGLRKGHSLLGQGLSTLQSEQGRLIQLLSESQGHMAHLVNSVSDVLEALQRERGLGRPRVKADLQRAPSRGARPRGCANGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWEAYREGFGKLTGEHWLGLKRIHALTTQAAYELHVDLEDFDNGTAYAHYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGPHASYADGVEWSSWTGWQYSLKFSEMKIRPLREDR", "length": 459 }, "evidence": [ { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QC51-1", "protein_name": "Microfibril-associated glycoprotein 4", "gene_name": "mfap4.11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAMTVFVVALLSVFTASVVSGFKPFDCSEIYKSGQTVSGVYSIYPAGDTPVWVYCQMISDGKDEENGGWTVFQRRMDGRINFYQPWEVYKRGFGTTEGEYWLGLENLYQLTRHKKFMLRVDLEDFEGRKVFAQYSSFSVGSEAEGYKLQVSGFTDGGAGDSLSAHNDRKFSTLDKDQDLYEKNCARYFLGGFWYTVGCHYTNPNGMYLWGEHNTRYAIGVVWSTWKNSFTLSMKTFLMKIKPVS", "length": 244 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R707-1", "protein_name": "Microfibril-associated glycoprotein 4", "gene_name": "mfap4.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMTVFVVALLSVFTASVVSGFKPFDCSEIYKSGKTLSGVYSIYPAGNIPASVYCQMISSGKGGENGGWTVFQRRMDGSVNFFRPWEEYKRGFGNVEGEYWLGLENLYQLTRHKKFMLRVDLEDFEGRKGFAQYSSFSVGSEAEGYKLQVSGFTNGGAGDSLIYHSGMKFTTYDKDQDTHTQNCARIYVGAFWYKDCHNANPNGVYLGGEDKTLFAIGNVWYTWKNNFEIGMKFITMKIKPVY", "length": 242 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA44-1", "protein_name": "Microfibril-associated glycoprotein 4", "gene_name": "mfap4.12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMMTSMVFLVALLSIVLVNGCSEDEDSPVDCSELNKAGETLSGVYTIHPAGDAPVWVYCQMVSDGKDEENGGWTVIQRRMDGSVNFYRPWRDYKRGFGNLEGEYWLGLENLYQLTRHKDHMLRVDLEDFEGRKGFAQYSSFSVGCETDGYQLQVSGFTDGGAGDSMTYHNGMKFSTFDKDQDNFDKSCARLYLGAFWYDNCHHANPNGVYLWGEDATIFAIGNVWYGWKNNYGIGMKSITMKIKHVP", "length": 247 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F8W539-1", "protein_name": "Microfibril-associated glycoprotein 4-like precursor", "gene_name": "mfap4.13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMASMVFLVALLSIVLVNGCSEDEDSPVDCSDLKKAGETLSGVYTIHPAGETPVWVYCQMVSDGKDEENGGWTVFQRRMDGSVNFYRPWRDYKRGFGNVEGEYWLGLENLYQLTRHKKFMLRVDLEDFTGRKGFAQYSSFSVGCETDGYKLQVSGFKDGGAGDSMTYHNGMKFSTFDKDQDNFDKSCARLYLGAFWYNNCHHANLNGVYLWGEDATIFAIGNVWYGWKSNYGIGMKSITMKIKHVP", "length": 246 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3V6A9-1", "protein_name": "Microfibril-associated glycoprotein 4", "gene_name": "Mfap4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSLNLEVMGLGRLVALQLRTALPSAGIAGMLCLYPCLCAACAGGPQRPESASDLLGLELEVPGTCQTLSGLPLLLLLLSTPPPCAPQASGIRGDALEKSCLQQPLDCDDIYMQGYQEDGVYLIYPYGPSVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNLHLLTLKQKYELRVDLEDFENNTAYAKYVDFSISPNAVSAEEDGYTLYVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLSYANGINWAQWKGFYYSLKRTEMKIRRA", "length": 323 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-14#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" }, { "id": "RGD:1307841", "url": "https://alliancegenome.org/gene/RGD:1307841#orthology", "database": "AGR" }, { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" }, { "id": "FB:FBgn0034160", "url": "https://alliancegenome.org/gene/FB:FBgn0034160#orthology", "database": "AGR" }, { "id": "FB:FBgn0033312", "url": "https://alliancegenome.org/gene/FB:FBgn0033312#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O70165-1", "protein_name": "Ficolin-1", "gene_name": "Fcn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQWPTLWAFSGLLCLCPSQALGQERGACPDVKVVGLGAQDKVVVIQSCPGFPGPPGPKGEPGSPAGRGERGFQGSPGKMGPAGSKGEPGTMGPPGVKGEKGDTGAAPSLGEKELGDTLCQRGPRSCKDLLTRGIFLTGWYTIHLPDCRPLTVLCDMDVDGGGWTVFQRRVDGSIDFFRDWDSYKRGFGNLGTEFWLGNDYLHLLTANGNQELRVDLQDFQGKGSYAKYSSFQVSEEQEKYKLTLGQFLEGTAGDSLTKHNNMSFTTHDQDNDANSMNCAALFHGAWWYHNCHQSNLNGRYLSGSHESYADGINWGTGQGHHYSYKVAEMKIRAS", "length": 334 }, "evidence": [ { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O70497-1", "protein_name": "Ficolin-2", "gene_name": "Fcn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGSAALFVLTLTVHAAGTCPELKVLDLEGYKQLTILQGCPGLPGAAGPKGEAGAKGDRGESGLPGIPGKEGPTGPKGNQGEKGIRGEKGDSGPSQSCATGPRTCKELLTQGHFLTGWYTIYLPDCRPLTVLCDMDTDGGGWTVFQRRLDGSVDFFRDWTSYKRGFGSQLGEFWLGNDNIHALTTQGTSELRVDLSDFEGKHDFAKYSSFQIQGEAEKYKLILGNFLGGGAGDSLTPHNNRLFSTKDQDNDGSTSSCAMGYHGAWWYSQCHTSNLNGLYLRGPHKSYANGVNWKSWRGYNYSCKVSEMKVRLI", "length": 314 }, "evidence": [ { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O75636-1", "protein_name": "Ficolin-3", "gene_name": "FCN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLLWILPSLWLLLLGGPACLKTQEHPSCPGPRELEASKVVLLPSCPGAPGSPGEKGAPGPQGPPGPPGKMGPKGEPGDPVNLLRCQEGPRNCRELLSQGATLSGWYHLCLPEGRALPVFCDMDTEGGGWLVFQRRQDGSVDFFRSWSSYRAGFGNQESEFWLGNENLHQLTLQGNWELRVELEDFNGNRTFAHYATFRLLGEVDHYQLALGKFSEGTAGDSLSLHSGRPFTTYDADHDSSNSNCAVIVHGAWWYASCYRSNLNGRYAVSEAAAHKYGIDWASGRGVGHPYRRVRMMLR", "length": 299 }, "evidence": [ { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P55083-1", "protein_name": "Microfibril-associated glycoprotein 4", "gene_name": "MFAP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKALLALPLLLLLSTPPCAPQVSGIRGDALERFCLQQPLDCDDIYAQGYQSDGVYLIYPSGPSVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGWNDYKLGFGRADGEYWLGLQNMHLLTLKQKYELRVDLEDFENNTAYAKYADFSISPNAVSAEEDGYTLFVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLSYANGINWAQWKGFYYSLKRTEMKIRRA", "length": 255 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-14#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" }, { "id": "RGD:1307841", "url": "https://alliancegenome.org/gene/RGD:1307841#orthology", "database": "AGR" }, { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" }, { "id": "FB:FBgn0034160", "url": "https://alliancegenome.org/gene/FB:FBgn0034160#orthology", "database": "AGR" }, { "id": "FB:FBgn0033312", "url": "https://alliancegenome.org/gene/FB:FBgn0033312#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P57756-1", "protein_name": "Ficolin-2", "gene_name": "Fcn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLGSAALFVLSLCVTELTLHAADTCPEVKVLDLEGSNKLTILQGCPGLPGALGPKGEAGAKGDRGESGLPGHPGKAGPTGPKGDRGEKGVRGEKGDTGPSQSCATGPRTCKELLTRGYFLTGWYTIYLPDCRPLTVLCDMDTDGGGWTVFQRRIDGTVDFFRDWTSYKQGFGSQLGEFWLGNDNIHALTTQGTNELRVDLADFDGNHDFAKYSSFQIQGEAEKYKLILGNFLGGGAGDSLTSQNNMLFSTKDQDNDQGSSNCAVRYHGAWWYSDCHTSNLNGLYLRGLHKSYANGVNWKSWKGYNYSYKVSEMKVRLI", "length": 319 }, "evidence": [ { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q05546-1", "protein_name": "Tenascin-R", "gene_name": "Tnr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGIEGETVVLKNMLIGVNLILLGSMLKPSECRLEVTTERVQRQTVEEEGGASSYNTSSKEQPMVFNHVYNINVPLESLCSSGLEASAEQDVSAEDDTLAEYTGQTSDHESQVTFTHKINLPKKACPCASSAQVLQELLSRIEMLEREVSVLRDQCNTNCCQESAATGQLDYVPHCSGHGNFSFESCGCICNEGWFGKNCSEPYCPLGCSSRGVCVDGQCICDSEYSGDDCSELRCPTDCSSRGLCVDGECVCEEPYTGEDCRELRCPGDCSGKGQCANGTCLCQEGYAGEDCSQRRCLNACSGRGHCQEGLCICEEGYQGPDCSAVTPPEDLRVAGISDRSIELEWDGPMAVTEYVISYQPSLGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFTPKNNEGGVIAQLPSDVTSFNQTGLKPGEEYIVNVVALKEQARGPPTSASVSTVIDGPTQILVRDVSDTVAFVEWTPPRAKVDFILLKYGLVGGEGGKTTFRLQPPLSQYSVQALRPGSRYEVSISAVRGTNESDASSTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEAQEYKVVYSTLAGEQYHEVLVPKGIGPTTKTTLTDLVPGTEYGVGISAVMNSKQSIPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGISSEVTVPRDRTSYTLTDLEPGAEYIISITAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVLLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKNITISNVTKDSLTVSWSPPVAPFDYYEYPIDHPSGRLDSSVVPNTVTEFTITRLYPASQYEISLNSVRGREESERICTLVHTAMDSPMDLIATNITPTEALLQWKAPMGEVENYVIVLTHFAMAGETILVDGVSEEFQLVDLLPRTHYTVTMYATSGPLVSGTIATNFSTLLDPPANLTASEVTRQSALISWQPPRAAIENYVLTYKSTDGSRKELIVDAEDTWIRLEGLSENTDYTVLLQAAQEATRSSLTSTIFTTGGRVFSHPQDCAQHLMNGDTLSGVYTIFLNGELSHKLQVYCDMTTDGGGWIVFQRRQNGQTDFFRKWADYRVGFGNLEDEFWLGLDNYHRITAQGRYELRVDMRDGQEAVFAYYDKFAVEDSRSLYKLRIGGYNGTAGDSLSYHQGRPFSTEDRDNDVAVTNCAMSYKGAWWYKNCHRTNLNGKYGESRHSQGINWYHWKGHEFSIPFVEMKMRPYIHRLTAGRKRRALKF", "length": 1356 }, "evidence": [ { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" }, { "id": "FB:FBgn0034160", "url": "https://alliancegenome.org/gene/FB:FBgn0034160#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15485-1", "protein_name": "Ficolin-2", "gene_name": "FCN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELDRAVGVLGAATLLLSFLGMAWALQAADTCPEVKMVGLEGSDKLTILRGCPGLPGAPGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWYKNCHVSNLNGRYLRGTHGSFANGINWKSGKGYNYSYKVSEMKVRPA", "length": 313 }, "evidence": [ { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7KT80-1", "protein_name": "Fibrinogen C-terminal domain-containing protein", "gene_name": "DS00929.7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKSCFFVLFLWTLLFEVGQSSPHTCPSGSPNGIHQLMLPEEEPFQVTQCKTTARDWIVIQRRLDGSVNFNQSWFSYKDGFGDPNGEFFIGLQKLYLMTREQPHELFIQLKHGPGATVYAHFDDFQVDSETELYKLERVGKYSGTAGDSLRYHINKRFSTFDRDNDESSKNCAAEHGGGWWFHSCLSSSLNGLYFREGETGMLNGIHWGRWKFQSLTFVQIMIRPKYF", "length": 227 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8N539-1", "protein_name": "Fibrinogen C domain-containing protein 1", "gene_name": "FIBCD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNDRWKTMGGAAQLEDRPRDKPQRPSCGYVLCTVLLALAVLLAVAVTGAVLFLNHAHAPGTAPPPVVSTGAASANSALVTVERADSSHLSILIDPRCPDLTDSFARLESAQASVLQALTEHQAQPRLVGDQEQELLDTLADQLPRLLARASELQTECMGLRKGHGTLGQGLSALQSEQGRLIQLLSESQGHMAHLVNSVSDILDALQRDRGLGRPRNKADLQRAPARGTRPRGCATGSRPRDCLDVLLSGQQDDGVYSVFPTHYPAGFQVYCDMRTDGGGWTVFQRREDGSVNFFRGWDAYRDGFGRLTGEHWLGLKRIHALTTQAAYELHVDLEDFENGTAYARYGSFGVGLFSVDPEEDGYPLTVADYSGTAGDSLLKHSGMRFTTKDRDSDHSENNCAAFYRGAWWYRNCHTSNLNGQYLRGAHASYADGVEWSSWTGWQYSLKFSEMKIRPVREDR", "length": 461 }, "evidence": [ { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VCM7-1", "protein_name": "Fibrinogen gamma chain", "gene_name": "Fgg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSWSLQPPSFLLCCLLLLFSPTGLAYVATRDNCCILDERFGSFCPTTCGIADFLSSYQTDVDNDLRTLEDILFRAENRTTEAKELIKAIQVYYNPDQPPKPGMIDSATQKSKKMVEEIVKYEALLLTHETSIRYLQEIYNSNNQKITNLKQKVAQLEAQCQEPCKDSVQIHDTTGKDCQEIANKGAKESGLYFIRPLKAKQQFLVYCEIDGSGNGWTVLQKRIDGSLDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISMQSTIPYALRIQLKDWNGRTSTADYAMFRVGPESDKYRLTYAYFIGGDAGDAFDGYDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAGHLNGVYHQGGTYSKSSTTNGFDDGIIWATWKSRWYSMKETTMKIIPFNRLSIGEGQQHHMGGSKQAGDV", "length": 436 }, "evidence": [ { "id": "FB:FBgn0033312", "url": "https://alliancegenome.org/gene/FB:FBgn0033312#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D1H9-1", "protein_name": "Microfibril-associated glycoprotein 4", "gene_name": "Mfap4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKALPALPLMLMLLSMPPPCAPQASGIRGDALEKSCLQQPLDCDDIYAQGYQEDGVYLIYPYGPSVPVPVFCDMTTEGGKWTVFQKRFNGSVSFFRGWSDYKLGFGRADGEYWLGLQNLHLLTLKQKYELRVDLEDFENNTAYAKYIDFSISPNAISAEEDGYTLYVAGFEDGGAGDSLSYHSGQKFSTFDRDQDLFVQNCAALSSGAFWFRSCHFANLNGFYLGGSHLSYANGINWAQWKGFYYSLKRTEMKIRRA", "length": 257 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-14#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" }, { "id": "RGD:1307841", "url": "https://alliancegenome.org/gene/RGD:1307841#orthology", "database": "AGR" }, { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" }, { "id": "FB:FBgn0034160", "url": "https://alliancegenome.org/gene/FB:FBgn0034160#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VME7-1", "protein_name": "Fibrinogen C-terminal domain-containing protein", "gene_name": "AAF52372", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRSVWIYVAFLGLSFYSTEAMDSESFQNDTAIRNKPELKSLYKLVLALLEENQSNASTENIQKSSSDLNTTGLSGRYPSQCPTYPPAHGIYTVQVLGLKPFQVSCDAEIAGTGWTVMARRTSNKLNFFRSWAEYKNGFGQLDGDFFIGLDKLHAITKSQPHELYIHLEDFEGQTRYAHYDEIFIESENKFYAMTKLGEFTGDAGDSMIHNRNQNFSTFDRDNDGWHKNCAEEYVGAWWHLNCTYSNLFGIYVKGDEGQYFQWKGIVWHSWRTESYSYKVMQMMVRPKCHCSG", "length": 292 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110408-14", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110408-14#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" }, { "id": "RGD:1307841", "url": "https://alliancegenome.org/gene/RGD:1307841#orthology", "database": "AGR" }, { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WTS8-1", "protein_name": "Ficolin-1", "gene_name": "Fcn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWWPMLWAFPVLLCLCSSQALGQESGACPDVKIVGLGAQDKVAVIQSCPSFPGPPGPKGEPGSPAGRGERGLQGSPGKMGPPGSKGEPGTMGPPGVKGEKGERGTASPLGQKELGDALCRRGPRSCKDLLTRGIFLTGWYTIYLPDCRPLTVLCDMDVDGGGWTVFQRRVDGSINFYRDWDSYKRGFGNLGTEFWLGNDYLHLLTANGNQELRVDLREFQGQTSFAKYSSFQVSGEQEKYKLTLGQFLEGTAGDSLTKHNNMAFSTHDQDNDTNGGKNCAALFHGAWWYHDCHQSNLNGRYLPGSHESYADGINWLSGRGHRYSYKVAEMKIRAS", "length": 335 }, "evidence": [ { "id": "FB:FBgn0031804", "url": "https://alliancegenome.org/gene/FB:FBgn0031804#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "R4GEG2-1", "protein_name": "Uncharacterized protein LOC100537823 precursor", "gene_name": "mfap4.10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MITVFVVALLSVFTMSVVSVCDGFKPFDCSEIYKSGQTGSGIYSIYPAGNTPVWVYCQMISEGKVQDNGGWTVFQRRLDGRINFYQPWEEYKRGFGTTEGEYWLGLENLYQLTRHKNYMLRVDLEDFTGRRGFAQYSSFSVGSEAEGYKLQISGFTDGGAGDSMTHHNGMKFSTYDKDQDIDSRNCARLRLGAFWYRNCYYANPNGVYIGGEDSTIYAIGDVWYSWKNNANFGMKLITMKIKPVS", "length": 245 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "R4GEQ7-1", "protein_name": "Microfibril-associated glycoprotein 4 isoform X1", "gene_name": "mfap4.8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAMTVFVVALLSVFTASVVSGFKPFDCSEIYKSGQTVSGIYSIYPAGDTPVWVYCQMVSDGKVEENEGWTVFQRRMDGSIHFFQLWEKYRIGFGTTEGEYWLGLENLYQLTRHKKFMLRVDLEDFTGRRGFAQYSSFSVGSEVEGYKLELSGFTDGGAGDSLSYHNGMKFSTYDRDQDTNEDNCARMRLGAFWYKGCNYANPNGVYLWGEDKSKNGIAINWYTWKNDNETPMKFITMKIKPVS", "length": 243 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" }, { "id": "RGD:1307841", "url": "https://alliancegenome.org/gene/RGD:1307841#orthology", "database": "AGR" }, { "id": "FB:FBgn0034160", "url": "https://alliancegenome.org/gene/FB:FBgn0034160#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "R4GES4-1", "protein_name": "Microfibril-associated glycoprotein 4-like", "gene_name": "mfap4.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAMTVFVVALLSVFTASVVSGFKPFDCSEIYKSGQTGSGIYSIYPAGDTPVWVYCEMVSRMMDGFNGGWTVFQRRMDGSINFYQPWEEYKKGFGTTEGEYWLGLENLYQLTRQKKFMLKVDLEDFTGRRGFAQYSSFSVGSEAEGYKLQVSAFTDGGAGDSLAYHNQMKFSTFDKDQDNSVKNCAKLNLGAFWYRDCHHTNPNGVYLWGEDATIFGIGNVWYAWTNKYATGLKSITMKIKPVS", "length": 243 }, "evidence": [ { "id": "HGNC:7035", "url": "https://alliancegenome.org/gene/HGNC:7035#orthology", "database": "AGR" }, { "id": "MGI:1342276", "url": "https://alliancegenome.org/gene/MGI:1342276#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6" } ], "pmid": "" }, { "name": "elastic fiber assembly", "id": "GO:0048251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048251", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z1Z6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z1Z6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Z6" }, { "id": "PS51406", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51406" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibrinogen C-terminal", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 242, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z201-1", "uniprot_ac": "A0A8M6Z201", "uniprot_id": "A0A8M6Z201_DANRE", "mass": { "chemical_mass": 24150.0, "monoisotopic_mass": 24150.0 }, "refseq": { "ac": "XP_017213984", "name": "tumor necrosis factor receptor superfamily member 13B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213984" }, "gene_names": [ { "name": "tnfrsf13b", "type": "recommended", "evidence": [ { "id": "A0A8M6Z201", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z201" } ] }, { "name": "tnfrsf13b", "type": "synonym", "evidence": [ { "id": "XP_017213984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213984" } ] } ], "protein_names": [ { "name": "Tumor necrosis factor receptor superfamily member 13B", "type": "synonym", "evidence": [ { "id": "A0A8M6Z201", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z201/entry#names_and_taxonomy" } ] }, { "name": "tumor necrosis factor receptor superfamily member 13B", "type": "synonym", "evidence": [ { "id": "XP_017213984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213984" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017213984.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213984" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z201", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z201" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tnfrsf13b", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z201", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z201", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z201", "database": "AlphaFoldDB", "categories": [] }, { "id": "103911891", "url": "https://www.ncbi.nlm.nih.gov/gene/103911891", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:103911891", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103911891", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z201", "url": "https://www.orthodb.org/?gene=A0A8M6Z201", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15511", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15511", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15511:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15511:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09305", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09305", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213984", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z201", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z201", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z201-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z201-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTHTCADGQFMDRLLIKCVSCDLRCAEPEPHKQCAEYCEVWRCRAVSGQFYDALLKKCLQCSDLCGTHTPACEHICSDPLVTGRGRTVSGSPLLLYALLGVCVTVLMFSLSAAVLTLLMRRNKHTQIPDEHKQQTSEDSLVAGSDEVSQEEGSVHHHHHHPQDRPRATETCVYCFSEHTARPHTLLQQAGDQDPESVPIPQDKCGALRIICSPTQTSL", "length": 218, "header": "tr|A0A8M6Z201-1|A0A8M6Z201_DANRE Isoform 1 of Tumor necrosis factor receptor superfamily member 13B OS=Danio rerio OX=7955 GN=tnfrsf13b PE=4 SV=2 CANONICAL=A0A8M6Z201-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z201-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z201/entry#A0A8M6Z201-1", "sequence": { "sequence": "MTHTCADGQFMDRLLIKCVSCDLRCAEPEPHKQCAEYCEVWRCRAVSGQFYDALLKKCLQCSDLCGTHTPACEHICSDPLVTGRGRTVSGSPLLLYALLGVCVTVLMFSLSAAVLTLLMRRNKHTQIPDEHKQQTSEDSLVAGSDEVSQEEGSVHHHHHHPQDRPRATETCVYCFSEHTARPHTLLQQAGDQDPESVPIPQDKCGALRIICSPTQTSL", "length": 218, "header": "tr|A0A8M6Z201-1|A0A8M6Z201_DANRE Isoform 1 of Tumor necrosis factor receptor superfamily member 13B OS=Danio rerio OX=7955 GN=tnfrsf13b PE=4 SV=2 CANONICAL=A0A8M6Z201-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103911891", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103911891", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z201", "url": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z213-1", "uniprot_ac": "A0A8M6Z213", "uniprot_id": "A0A8M6Z213_DANRE", "mass": { "chemical_mass": 61169.0, "monoisotopic_mass": 61169.0 }, "refseq": { "ac": "XP_017207014", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207014" }, "gene_names": [ { "name": "LOC108179621", "type": "recommended", "evidence": [ { "id": "A0A8M6Z213", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z213" } ] }, { "name": "LOC108179621", "type": "synonym", "evidence": [ { "id": "XP_017207014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207014" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M6Z213", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z213/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017207014", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207014" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017207014.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017207014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207014" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z213", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z213" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108179621", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z213", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z213", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z213", "database": "AlphaFoldDB", "categories": [] }, { "id": "108179621", "url": "https://www.ncbi.nlm.nih.gov/gene/108179621", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:108179621", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179621", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z213", "url": "https://www.orthodb.org/?gene=A0A8M6Z213", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_017207014", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207014", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z213", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z213", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z213-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z213-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEPTRSRVKDPKVEAGTDRSCVKGNWLDKKKLRNETEFYKLDLKITESGLTGNMGKNDKGPYNLPSARGTKGQSLMKHSKAKKTPEEQKKKESKGQLRKENSQNDPVTVKKFSKGPQLDLSNQISSGAGVQSKSEIDMTASVVQDKKGLSAESRHRTKVFESEKTKPGSRLNTKPGTSPSEISISDYLILLKCLRINLPDGVLNPKVIRLSQTANVIQKAQDIVKDLENLKLQFNSIPRLGSREVKISLSLKDNNKVLEITQMIFFEKTEGSDEDLRTQWKKNVSNTNCGFRFRDKYKTTAISVPAMYATAQTRSWRHLEDGEKHANISAGEPVNVSEIEKKDYRDESTLWTTSSPQRFGKYSLNPADERECLKFYHELCEIGASRTVKYTKGNKVESGFLSGRLDFLAELKGEKTERIVIECKGTTGDMVGKVFTKPTNGGRCAQLNETHEYYYQVQAYMYILNQSAKQTRRFTSDRAVMVIRHYHKNGQAPRDFYWNYLRKNEAIQQKINELCVFCEEEVLACFLAVLNLIFQKDT", "length": 538, "header": "tr|A0A8M6Z213-1|A0A8M6Z213_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108179621 PE=4 SV=2 CANONICAL=A0A8M6Z213-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z213-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z213/entry#A0A8M6Z213-1", "sequence": { "sequence": "MEPTRSRVKDPKVEAGTDRSCVKGNWLDKKKLRNETEFYKLDLKITESGLTGNMGKNDKGPYNLPSARGTKGQSLMKHSKAKKTPEEQKKKESKGQLRKENSQNDPVTVKKFSKGPQLDLSNQISSGAGVQSKSEIDMTASVVQDKKGLSAESRHRTKVFESEKTKPGSRLNTKPGTSPSEISISDYLILLKCLRINLPDGVLNPKVIRLSQTANVIQKAQDIVKDLENLKLQFNSIPRLGSREVKISLSLKDNNKVLEITQMIFFEKTEGSDEDLRTQWKKNVSNTNCGFRFRDKYKTTAISVPAMYATAQTRSWRHLEDGEKHANISAGEPVNVSEIEKKDYRDESTLWTTSSPQRFGKYSLNPADERECLKFYHELCEIGASRTVKYTKGNKVESGFLSGRLDFLAELKGEKTERIVIECKGTTGDMVGKVFTKPTNGGRCAQLNETHEYYYQVQAYMYILNQSAKQTRRFTSDRAVMVIRHYHKNGQAPRDFYWNYLRKNEAIQQKINELCVFCEEEVLACFLAVLNLIFQKDT", "length": 538, "header": "tr|A0A8M6Z213-1|A0A8M6Z213_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108179621 PE=4 SV=2 CANONICAL=A0A8M6Z213-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108179621", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179621", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" }, { "start_pos": 34, "end_pos": 36, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 465, "end_pos": 467, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 283, "end_pos": 285 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 335, "end_pos": 337 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 465, "end_pos": 467 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z242-1", "uniprot_ac": "A0A8M6Z242", "uniprot_id": "A0A8M6Z242_DANRE", "mass": { "chemical_mass": 49417.0, "monoisotopic_mass": 49417.0 }, "refseq": { "ac": "XP_017214090", "name": "pyroglutamylated RF-amide peptide receptor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214090" }, "gene_names": [ { "name": "qrfprb", "type": "recommended", "evidence": [ { "id": "A0A8M6Z242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242" } ] }, { "name": "qrfprb", "type": "synonym", "evidence": [ { "id": "XP_017214090", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214090" } ] } ], "protein_names": [ { "name": "Pyroglutamylated RF-amide peptide receptor", "type": "recommended", "evidence": [ { "id": "A0A8M6Z242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242/entry#names_and_taxonomy" } ] }, { "name": "AQ27", "type": "synonym", "evidence": [ { "id": "A0A8M6Z242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 103", "type": "synonym", "evidence": [ { "id": "A0A8M6Z242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242/entry#names_and_taxonomy" } ] }, { "name": "Orexigenic neuropeptide QRFP receptor", "type": "synonym", "evidence": [ { "id": "A0A8M6Z242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242/entry#names_and_taxonomy" } ] }, { "name": "SP9155", "type": "synonym", "evidence": [ { "id": "A0A8M6Z242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242/entry#names_and_taxonomy" } ] }, { "name": "pyroglutamylated RF-amide peptide receptor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017214090", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214090" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017214090.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214090", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214090" } ] }, { "annotation": "Receptor for the orexigenic neuropeptide QRFP. The activity of this receptor is mediated by G proteins that modulate adenylate cyclase activity and intracellular calcium levels.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z242", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242#function" }, { "database": "UniProtKB", "id": "ARBA00059793", "url": "https://www.uniprot.org/uniprotkb/ARBA00059793#function" } ] } ], "disease": [ { "disease_id": "DOID:0080010", "recommended_name": { "id": "DOID:0080010", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080010", "name": "bone structure disease", "description": "A bone disease that has_material_basis_in an abnormality in the location or function of the skeletal structure." }, "synonyms": [], "unlinked_id_list": [ "DOID:0080007" ], "evidence": [ { "id": "0080010", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080010" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z242", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "qrfprb", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131125-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131125-15", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z242", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z242", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15205", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15205", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101886159", "url": "https://www.ncbi.nlm.nih.gov/gene/101886159", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101886159", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886159", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z242", "url": "https://www.orthodb.org/?gene=A0A8M6Z242", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24241:SF143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24241:SF143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017214090", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214090", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z242", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z242-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GZA3", "url": "https://www.uniprot.org/uniprotkb/A0AC58GZA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GZA3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GZA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131125-15", "url": "https://zfin.org/ZDB-GENE-131125-15", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSSSTEMTATTKITPEVLQELLQYYNLSRQEFIDTYNIQPLVYIPELPAGVKSTFVVMYVIIFVLALVGNSLVVYVVVRKRAIRTATNIFICSLAVSDLLITFFCIPFTLLQNISSEWLGGVLVCKTVPFVQTTAIVTGILTMTCIAIERYQGIVYPLKMKRQYTPKRAYRMLGLVWIAAVMVGSPMLFVQQLEVKYDFLYDHHHVCCQERWQSLLQRQLYTTFIMVALFLLPLAAMLFLYSRIGVELWIRKRVGDASVLSTMNHREISKISRKKKRAVKMMITIVLLFTVCWAPFHIVHMLFEYNDLEKKYNEVTVNMIIAVVQAIGFSNSFNNPIVYAFMNENFKKSCLSTLSSYLRRPVQQSVPRQNLSVHFSKHLKTEAFSGAEEHLEPQHNRLLSSSQGELEISTAFPEQNGQTSSSQLPSSSSCVK", "length": 433, "header": "tr|A0A8M6Z242-1|A0A8M6Z242_DANRE Isoform 1 of Pyroglutamylated RF-amide peptide receptor OS=Danio rerio OX=7955 GN=qrfprb PE=3 SV=2 CANONICAL=A0A8M6Z242-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z242-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242/entry#A0A8M6Z242-1", "sequence": { "sequence": "MSSSSTEMTATTKITPEVLQELLQYYNLSRQEFIDTYNIQPLVYIPELPAGVKSTFVVMYVIIFVLALVGNSLVVYVVVRKRAIRTATNIFICSLAVSDLLITFFCIPFTLLQNISSEWLGGVLVCKTVPFVQTTAIVTGILTMTCIAIERYQGIVYPLKMKRQYTPKRAYRMLGLVWIAAVMVGSPMLFVQQLEVKYDFLYDHHHVCCQERWQSLLQRQLYTTFIMVALFLLPLAAMLFLYSRIGVELWIRKRVGDASVLSTMNHREISKISRKKKRAVKMMITIVLLFTVCWAPFHIVHMLFEYNDLEKKYNEVTVNMIIAVVQAIGFSNSFNNPIVYAFMNENFKKSCLSTLSSYLRRPVQQSVPRQNLSVHFSKHLKTEAFSGAEEHLEPQHNRLLSSSQGELEISTAFPEQNGQTSSSQLPSSSSCVK", "length": 433, "header": "tr|A0A8M6Z242-1|A0A8M6Z242_DANRE Isoform 1 of Pyroglutamylated RF-amide peptide receptor OS=Danio rerio OX=7955 GN=qrfprb PE=3 SV=2 CANONICAL=A0A8M6Z242-1" }, "locus": {} }, { "isoform_ac": "A0AC58GZA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242/entry#A0AC58GZA3-1", "sequence": { "sequence": "MQDSSFCTDHSHRNWNPHHDLHRHREIPGHSVSAQNEAAVHAETGLQDARAGVDRCCHGRISNAVRTTVRVFPVCVSQVKYDFLYDHHHVCCQERWQSLLQRQLYTTFIMVALFLLPLAAMLFLYSRIGVELWIRKRVGDASVLSTMNHREISKISRKKKRAVKMMITIVLLFTVCWAPFHIVHMLFEYNDLEKKYNEVTVNMIIAVVQAIGFSNSFNNPIVYAFMNENFKKSCLSTLSSYLRRPVQQSVPRQNLSVHFSKHLKTEAFSGAEEHLEPQHNRLLSSSQGELEISTAFPEQNGQTSSSQLPSSSSCVK", "length": 316, "header": "tr|A0AC58GZA3-1|A0AC58GZA3_DANRE Computationally mapped isoform of Pyroglutamylated RF-amide peptide receptor isoform X2 OS=Danio rerio OX=7955 GN=qrfprb PE=4 SV=1 CANONICAL=A0A8M6Z242-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101886159", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886159", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AD76-1", "protein_name": "Pyroglutamylated RF-amide peptide receptor", "gene_name": "Qrfprl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWNLTAEQLSALLQLHNLTRAQFIARYGLRPLVLTPQLPARARLALLLAGLLIFALALFGNALVVYVVTRSKAMRTVTNIFICSLALSDLLIVFFCIPVTMLQNVSDTWLGGAFICKMVPFVQCTAVVTEILTMTCIAVERHQGLVHPFKMKQQYTNQRAFTMLGVVWLVAIIIGSPMWHVQRLEIKYDFLYEKEHICCLEEWSSPVHQKIYTTFILVTLFLLPLLLLSVLYGKIGYELWIKKRVGDGSVLRTIHGKEMFKIARKKKRAVIMMVTVVVLFAVCWAPFHVVHMMIEYSNFEKEYDEVTIKMIFAIVQIIGFFNSICNPIVYALMNENFKKNFVSAVCYCVIKETPSPAQRHGSLGAIVMHRRVKLAVGENPVEIKGEAFGGSNMDIKWCEQPEKKKKSQMASCPL", "length": 415 }, "evidence": [ { "id": "RGD:1560028", "url": "https://alliancegenome.org/gene/RGD:1560028#orthology", "database": "AGR" }, { "id": "HGNC:15565", "url": "https://alliancegenome.org/gene/HGNC:15565#orthology", "database": "AGR" }, { "id": "MGI:2441881", "url": "https://alliancegenome.org/gene/MGI:2441881#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131125-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131125-15#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3UWA8-1", "protein_name": "Pyroglutamylated RF-amide peptide receptor", "gene_name": "Qrfprl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSWNLTAEQLSALLRLHNLTRAQFIAHYGLRPLVLTPQLPARARLALLLVGMLIFALALFGNALVVYVVTRSKAMRTVTNIFICSLALSDLLIVFFCIPVTMLQNVSDTWLGGAFICKMVPFVQCTAIVTEILTMTCIAVERHQGLVHPFKMKRQYTNQRAFTMLGVVWLVAIIIGSPMWHVQRLEIKYDFLYEKEHICCLEEWSSPVHQKIYTTFILVTLFLLPLLLLSVLYGKIGYELWIKKRIGDGSVLRTIHGKEMFKIARKKKRAVIMMVTVVVLFAVCWAPFHIVHMMIEYSNFEKEYDEVTIKMIFAIVQIIGFFNSICNPIIYALMNENFKKNFVSAVCYCIVKETPSSARKHGSSGAMVMHRRAKLAARENPVEIKGEAFGGSNIDIKWCEQPEKKKRRSKVASCPL", "length": 416 }, "evidence": [ { "id": "RGD:1560028", "url": "https://alliancegenome.org/gene/RGD:1560028#orthology", "database": "AGR" }, { "id": "HGNC:15565", "url": "https://alliancegenome.org/gene/HGNC:15565#orthology", "database": "AGR" }, { "id": "MGI:2441881", "url": "https://alliancegenome.org/gene/MGI:2441881#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131125-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131125-15#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P83858-1", "protein_name": "Pyroglutamylated RF-amide peptide receptor", "gene_name": "Qrfpr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQALNITAEQFSRLLSAHNLTREQFIHRYGLRPLVYTPELPARAKVAFALAGALIFALALFGNSLVIYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPVTMLQNISDKWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTTRRAFTILGVVWLAAIIVGSPMWHVQRLEIKYDFLYEKEHICCLEEWASPVHQRIYSTFILVILFLLPLVVMLVLYSKIGYELWIKKRVGDSSALQTIHGKEMSKIARKKKRAVIMMVTVVALFAACWAPFHVVHMMVEYSNFEKEYDDVTIKMVFAVAQTIGFFNSICNPFVYAFMNENFKKNFLSAVCYCIVKESSSPARKPGNSGISMMQKRAKLSRPQRPVEETKGDTFSDASIDVKLCEQPREKRQLKRQLAFFSSELSENSTFGSGHEL", "length": 433 }, "evidence": [ { "id": "RGD:728380", "url": "https://alliancegenome.org/gene/RGD:728380#orthology", "database": "AGR" }, { "id": "HGNC:15565", "url": "https://alliancegenome.org/gene/HGNC:15565#orthology", "database": "AGR" }, { "id": "MGI:2677633", "url": "https://alliancegenome.org/gene/MGI:2677633#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131125-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131125-15#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83861-1", "protein_name": "Pyroglutamylated RF-amide peptide receptor", "gene_name": "Qrfpr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQALNITAEQFSRLLSAHNLTREQFIHRYGLRPLVYTPELPARAKLAFALAGALIFALALFGNSLVIYVVTRSKAMRTVTNIFICSLALSDLLIAFFCIPVTMLQNISDKWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLIHPFKMKWQYTTRRAFTILGVVWLAAIIVGSPMWHVQRLEIKYDFLYEKEHVCCLEEWASPMHQRIYTTFILVILFLLPLVVMLVLYSKIGYELWIKKRVGDSSALQTIHGKEMSKIARKKKRAVVMMVTVVALFAACWAPFHVVHMMVEYSNFEKEYDDVTIKMVFAVAQTIGFFNSICNPFVYAFMNENFKKNFLSAVCYCIVRETFSPGQKPGNSGISMMQKRAKLSRSQRPVAEAKGDLFSDANVDVKLCEQPGEKRQLKRQLAFFSSELSENSTFGSGHEL", "length": 433 }, "evidence": [ { "id": "RGD:728380", "url": "https://alliancegenome.org/gene/RGD:728380#orthology", "database": "AGR" }, { "id": "HGNC:15565", "url": "https://alliancegenome.org/gene/HGNC:15565#orthology", "database": "AGR" }, { "id": "MGI:2677633", "url": "https://alliancegenome.org/gene/MGI:2677633#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131125-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131125-15#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96P65-1", "protein_name": "Pyroglutamylated RF-amide peptide receptor", "gene_name": "QRFPR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQALNITPEQFSRLLRDHNLTREQFIALYRLRPLVYTPELPGRAKLALVLTGVLIFALALFGNALVFYVVTRSKAMRTVTNIFICSLALSDLLITFFCIPVTMLQNISDNWLGGAFICKMVPFVQSTAVVTEILTMTCIAVERHQGLVHPFKMKWQYTNRRAFTMLGVVWLVAVIVGSPMWHVQQLEIKYDFLYEKEHICCLEEWTSPVHQKIYTTFILVILFLLPLMVMLILYSKIGYELWIKKRVGDGSVLRTIHGKEMSKIARKKKRAVIMMVTVVALFAVCWAPFHVVHMMIEYSNFEKEYDDVTIKMIFAIVQIIGFSNSICNPIVYAFMNENFKKNVLSAVCYCIVNKTFSPAQRHGNSGITMMRKKAKFSLRENPVEETKGEAFSDGNIEVKLCEQTEEKKKLKRHLALFRSELAENSPLDSGH", "length": 431 }, "evidence": [ { "id": "RGD:728380", "url": "https://alliancegenome.org/gene/RGD:728380#orthology", "database": "AGR" }, { "id": "RGD:1560028", "url": "https://alliancegenome.org/gene/RGD:1560028#orthology", "database": "AGR" }, { "id": "HGNC:15565", "url": "https://alliancegenome.org/gene/HGNC:15565#orthology", "database": "AGR" }, { "id": "MGI:2677633", "url": "https://alliancegenome.org/gene/MGI:2677633#orthology", "database": "AGR" }, { "id": "MGI:2441881", "url": "https://alliancegenome.org/gene/MGI:2441881#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131125-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131125-15#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VML9-1", "protein_name": "Trissin receptor", "gene_name": "TrissinR", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIMTMMQTVRAWQQESDVEHRKQHKQRWRPDGAHISAAYDLNSDNDDGHHRVVHNQNNGSPNSSPNQSTSAFRQRQPHHPPTGQQPPRLPCTVTHFSAHWKTLLILLTLLSASTLTASANVTSTISPPINGSSTDYILLYGESTTSLVPALTTGLSGDGSGAVIEDEEDAEKASEYIFDRTDVRIIFITLYTLVFCCCFFGNLLVILVVTLSRRLRSITNFFLANLAFADFCVGLFCVMQNLSIYLIESWVFGEFLCRMYQFVHSLSYTASIFILVVICMERYFAIVHPITCKQILTAARLRMVIVTVWITSAVYSTPKFVFSKTIKNIHTQDGQEEEICVLDREMFNSKLLDMINFVLLYVMPLLVMTVLYSKIAIALWRSSRGLTPHVVQHQHQQPQQPSCQDIGMGMHNSMYHHHPHHHHHHHQHHQLQSAASSAGVVGVGLGGGGGGGPGPSLASGGSSTTSLSRKQSSKYEKRGVSITESQLDNCKVSLEADRPIVSACRKTSFYHHGHAHHQRAGNASVGGGSGGAGAGATHMSHSSSNVLRARRGVVRMLIIFVLTFALCNLPYHARKMWQYWSRSYRGDSNFNALLTPLTFLVTYFNSGVNPLLYAFLSRNFRKGMKELLLCSWKKGKGKSSSNSSMHHKRKALQTHSLPTDTTHIGNEQL", "length": 669 }, "evidence": [ { "id": "RGD:728380", "url": "https://alliancegenome.org/gene/RGD:728380#orthology", "database": "AGR" }, { "id": "RGD:1560028", "url": "https://alliancegenome.org/gene/RGD:1560028#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z242", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242" } ], "pmid": "" }, { "name": "neuropeptide receptor activity", "id": "GO:0008188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008188", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z242", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242" } ], "pmid": "" }, { "name": "neuropeptide Y receptor activity", "id": "GO:0004983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004983", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z242", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z242", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z242", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z242", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242" } ], "pmid": "" }, { "name": "locomotory behavior", "id": "GO:0007626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007626", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z242", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242" } ], "pmid": "" }, { "name": "cellular response to hormone stimulus", "id": "GO:0032870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032870", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z242", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242" } ], "pmid": "" }, { "name": "sleep", "id": "GO:0030431", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030431", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z242", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z242", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z242" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 70, "end_pos": 340, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 371, "end_pos": 373 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z247-1", "uniprot_ac": "A0A8M6Z247", "uniprot_id": "A0A8M6Z247_DANRE", "mass": { "chemical_mass": 26713.0, "monoisotopic_mass": 26713.0 }, "refseq": { "ac": "XP_017214555", "name": "uncharacterized protein si:dkey-201i24.3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214555" }, "gene_names": [ { "name": "si:dkey-201i24.3", "type": "recommended", "evidence": [ { "id": "A0A8M6Z247", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z247" } ] }, { "name": "si:dkey-201i24.3", "type": "synonym", "evidence": [ { "id": "XP_017214555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214555" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkey-201i24.3", "type": "synonym", "evidence": [ { "id": "A0A8M6Z247", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z247/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkey-201i24.3", "type": "synonym", "evidence": [ { "id": "XP_017214555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214555" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017214555.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214555" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z247", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z247" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-201i24.3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z247", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141216-307", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141216-307", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z247", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z247", "database": "AlphaFoldDB", "categories": [] }, { "id": "103912057", "url": "https://www.ncbi.nlm.nih.gov/gene/103912057", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:103912057", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103912057", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z247", "url": "https://www.orthodb.org/?gene=A0A8M6Z247", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR40710", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40710", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR40710:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR40710:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_017214555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214555", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z247", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z247", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z247-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z247-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-141216-307", "url": "https://zfin.org/ZDB-GENE-141216-307", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDSSGEGARAEVCETSDRKRDLQQLLRQEMEMHITEGRASVQRNQERMSRIRQLKEELHKEEIKLQEPDQSQAMSTVDYEKILERRARLKETHERLIENELMKMERELQEEQAGGVEGEMSYLRRERLVLVLQIETLRRENQQAYADLEQQNQRHQQELNLLREESLQVFRAFRDVLEEQKRMSESRYRTLLIDAIQDAVHLSSQNLQLHEEIQQLRKTSQSQ", "length": 223, "header": "tr|A0A8M6Z247-1|A0A8M6Z247_DANRE Isoform 1 of Uncharacterized protein si:dkey-201i24.3 OS=Danio rerio OX=7955 GN=si:dkey-201i24.3 PE=4 SV=3 CANONICAL=A0A8M6Z247-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z247-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z247/entry#A0A8M6Z247-1", "sequence": { "sequence": "MDSSGEGARAEVCETSDRKRDLQQLLRQEMEMHITEGRASVQRNQERMSRIRQLKEELHKEEIKLQEPDQSQAMSTVDYEKILERRARLKETHERLIENELMKMERELQEEQAGGVEGEMSYLRRERLVLVLQIETLRRENQQAYADLEQQNQRHQQELNLLREESLQVFRAFRDVLEEQKRMSESRYRTLLIDAIQDAVHLSSQNLQLHEEIQQLRKTSQSQ", "length": 223, "header": "tr|A0A8M6Z247-1|A0A8M6Z247_DANRE Isoform 1 of Uncharacterized protein si:dkey-201i24.3 OS=Danio rerio OX=7955 GN=si:dkey-201i24.3 PE=4 SV=3 CANONICAL=A0A8M6Z247-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103912057", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103912057", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A2R0-1", "protein_name": "Riken cDNA E230025N22 gene like", "gene_name": "E230025N22Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLASVGQGYSIALLLQGQDTEAPRFVPQVLQMLFEEALPLCSSDPVLCTLSLVQISRSGQARDLLSPCLEDLPVLDVAPLGLVVKDASEVEVSDARDASELYLKAAGSEGRDCPLLQVLGGDPTGEEAEGSLPWIISWLLEANSYSGVLLRLDPRGSSPSLLQNVLLGASRKRVQVNDVKPTLWNAIEEMRARRATLKMLRSGLLGDTLTDGGLNRLGRALWELQVVKAWDPRSHAPKGAKSVRLPEPQVEGEPLSSCKQGRHSAHLSEAGRGFLGSGLHQKHPLRHSEEWAHQAPDVALQFSLAQARRQRLREEHQVWIQEELKHLEHRKEAACKQIEGTVAEEACVERGGQWKEQAVLKLQVEALQAERDMAEQDLAVLYDLYVQAARARTCHLLQVFQAWQGMWEEKAMATEHRHRSLLADILQDTIDLALKNQELQAQNQQPEQGADRASCAEILPGET", "length": 463 }, "evidence": [ { "id": "RGD:1565779", "url": "https://alliancegenome.org/gene/RGD:1565779#orthology", "database": "AGR" }, { "id": "MGI:3687212", "url": "https://alliancegenome.org/gene/MGI:3687212#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141216-307", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141216-307#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G5E8S3-1", "protein_name": "Riken cDNA E230025N22 gene", "gene_name": "E230025N22Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLASVGQGYNTTLLLQGQETEAPRFVPQVLQMLFEEALPLCSSGPVLCTLSLVQINRIGQARDLLSPCVEDLPVLDVAPLGLVVKDASEVEVSDARAASELYLKAAVGEGRDCPLLRVLAGAAAGEEVEGSLPWIISWLLEANSYRGVLLRLDPRGSSLSLLQNALLGASRKRMQVNDVKPTLWSAVEEMGARRATLKMLRLGLLGDTLTYSGLNQLGRALWELQVVKAWGPRSHTHKGTRDETVRLLEPQVKGEPLNYCKQGRHSAHLSEAGRRGFLGSGLRLKHPLGHCEEQAHQAPDVALQFSLAQARRQRLREEHQIRIQEELKHLEHWKEVATCEQIKGTVAEEACMGRESQRKEQAVLKLQVDTLQAERDVAEQDLVVLYDLYVQATRARTCHLLQVFQAWQRMWEEKAMATEHHYRSLLAGILQGSIDLALKNQQLQSQNQQLEQSADRASHAGVLPGETSDPEHSGATFLCPHS", "length": 482 }, "evidence": [ { "id": "RGD:1565779", "url": "https://alliancegenome.org/gene/RGD:1565779#orthology", "database": "AGR" }, { "id": "MGI:3687212", "url": "https://alliancegenome.org/gene/MGI:3687212#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141216-307", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141216-307#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z251-1", "uniprot_ac": "A0A8M6Z251", "uniprot_id": "A0A8M6Z251_DANRE", "mass": { "chemical_mass": 37887.0, "monoisotopic_mass": 37887.0 }, "refseq": { "ac": "XP_073786284", "name": "P2Y purinoceptor 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073786284" }, "gene_names": [ { "name": "p2ry2.3", "type": "recommended", "evidence": [ { "id": "A0A8M6Z251", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251" } ] }, { "name": "p2ry2.3", "type": "synonym", "evidence": [ { "id": "XP_073786284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073786284" } ] } ], "protein_names": [ { "name": "P2Y purinoceptor 2", "type": "recommended", "evidence": [ { "id": "A0A8M6Z251", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251/entry#names_and_taxonomy" } ] }, { "name": "P2Y purinoceptor 2", "type": "synonym", "evidence": [ { "id": "XP_073786284", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073786284" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073786284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073786284" } ] } ], "disease": [ { "disease_id": "DOID:1875", "recommended_name": { "id": "DOID:1875", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1875", "name": "impotence", "description": "A sexual dysfunction that is characterized by persistent or recurrent inability to achieve or to maintain an erection during sexual activity." }, "synonyms": [ { "id": "DOID:1875", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1875", "name": "Sexual impotence", "description": "" }, { "id": "DOID:1875", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1875", "name": "erectile dysfunction", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1875", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1875" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z251", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "p2ry2.3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-458", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-458", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "799661", "url": "https://www.ncbi.nlm.nih.gov/gene/799661", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:799661", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799661", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z251", "url": "https://www.orthodb.org/?gene=A0A8M6Z251", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24231:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24231:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073786284", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073786284", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z251", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z251-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-458", "url": "https://zfin.org/ZDB-GENE-091204-458", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAMNNTTVSTNDIDIYRCTLKEDFKYILLPVSYSLVFVFGLGLNITAMYVILFRTKHWKPNTIYMINLNACDTLYILTLPFLIYYYAGANAWPFGDPMCRFIRFFFYTNLYGSILFLSCISVHRFIGVCHPVRSLSWMNARRARWISVGIWLIILILQTPLLYFSRTRLNDEVLVCHDTTIKELFDDFLVYSSVVMLLLFVLPFGVVLVCNFLIVKKLREPGVGDAPTSQRSKQKSVKMIIIVLVAFMLCFLPFHVNRSVYYTLRYLDQANCTVIRLSNNVYKATRPLVSFNSCIDPILYFMAGQSFRKSIKKTSSQRYDKSMSTY", "length": 326, "header": "tr|A0A8M6Z251-1|A0A8M6Z251_DANRE Isoform 1 of P2Y purinoceptor 2 OS=Danio rerio OX=7955 GN=p2ry2.3 PE=3 SV=2 CANONICAL=A0A8M6Z251-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z251-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251/entry#A0A8M6Z251-1", "sequence": { "sequence": "MAMNNTTVSTNDIDIYRCTLKEDFKYILLPVSYSLVFVFGLGLNITAMYVILFRTKHWKPNTIYMINLNACDTLYILTLPFLIYYYAGANAWPFGDPMCRFIRFFFYTNLYGSILFLSCISVHRFIGVCHPVRSLSWMNARRARWISVGIWLIILILQTPLLYFSRTRLNDEVLVCHDTTIKELFDDFLVYSSVVMLLLFVLPFGVVLVCNFLIVKKLREPGVGDAPTSQRSKQKSVKMIIIVLVAFMLCFLPFHVNRSVYYTLRYLDQANCTVIRLSNNVYKATRPLVSFNSCIDPILYFMAGQSFRKSIKKTSSQRYDKSMSTY", "length": 326, "header": "tr|A0A8M6Z251-1|A0A8M6Z251_DANRE Isoform 1 of P2Y purinoceptor 2 OS=Danio rerio OX=7955 GN=p2ry2.3 PE=3 SV=2 CANONICAL=A0A8M6Z251-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:799661", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799661", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P35383-1", "protein_name": "P2Y purinoceptor 2", "gene_name": "P2ry2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADLEPWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLRWGRARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSVILVCYVLMARRLLKPAYGTTGGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTEPTPSPQARRKLGLHRPNRTVRKDLSVSSDDSRRTESTPAGSETKDIRL", "length": 373 }, "evidence": [ { "id": "RGD:62088", "url": "https://alliancegenome.org/gene/RGD:62088#orthology", "database": "AGR" }, { "id": "MGI:105107", "url": "https://alliancegenome.org/gene/MGI:105107#orthology", "database": "AGR" }, { "id": "HGNC:8541", "url": "https://alliancegenome.org/gene/HGNC:8541#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-458", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-458#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P41231-1", "protein_name": "P2Y purinoceptor 2", "gene_name": "P2RY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAADLGPWNDTINGTWDGDELGYRCRFNEDFKYVLLPVSYGVVCVPGLCLNAVALYIFLCRLKTWNASTTYMFHLAVSDALYAASLPLLVYYYARGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLRSLRWGRARYARRVAGAVWVLVLACQAPVLYFVTTSARGGRVTCHDTSAPELFSRFVAYSSVMLGLLFAVPFAVILVCYVLMARRLLKPAYGTSGGLPRAKRKSVRTIAVVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKVTRPLASANSCLDPVLYFLAGQRLVRFARDAKPPTGPSPATPARRRLGLRRSDRTDMQRIEDVLGSSEDSRRTESTPAGSENTKDIRL", "length": 377 }, "evidence": [ { "id": "RGD:62088", "url": "https://alliancegenome.org/gene/RGD:62088#orthology", "database": "AGR" }, { "id": "MGI:105107", "url": "https://alliancegenome.org/gene/MGI:105107#orthology", "database": "AGR" }, { "id": "HGNC:8541", "url": "https://alliancegenome.org/gene/HGNC:8541#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-458", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-458#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P41232-1", "protein_name": "P2Y purinoceptor 2", "gene_name": "P2ry2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGLDSWNSTINGTWEGDELGYKCRFNEDFKYVLLPVSYGVVCVLGLCLNVVALYIFLCRLKTWNASTTYMFHLAVSDSLYAASLPLLVYYYAQGDHWPFSTVLCKLVRFLFYTNLYCSILFLTCISVHRCLGVLRPLHSLSWGHARYARRVAAVVWVLVLACQAPVLYFVTTSVRGTRITCHDTSARELFSHFVAYSSVMLGLLFAVPFSIILVCYVLMARRLLKPAYGTTGLPRAKRKSVRTIALVLAVFALCFLPFHVTRTLYYSFRSLDLSCHTLNAINMAYKITRPLASANSCLDPVLYFLAGQRLVRFARDAKPATEPTPSPQARRKLGLHRPNRTDTVRKDLSISSDDSRRTESTPAGSETKDIRL", "length": 374 }, "evidence": [ { "id": "RGD:62088", "url": "https://alliancegenome.org/gene/RGD:62088#orthology", "database": "AGR" }, { "id": "MGI:105107", "url": "https://alliancegenome.org/gene/MGI:105107#orthology", "database": "AGR" }, { "id": "HGNC:8541", "url": "https://alliancegenome.org/gene/HGNC:8541#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-458", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-458#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "A1 adenosine receptor binding", "id": "GO:0031686", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031686", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z251", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251" } ], "pmid": "" }, { "name": "G protein-coupled UTP receptor activity", "id": "GO:0045030", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045030", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z251", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z251", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z251", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251" } ], "pmid": "" }, { "name": "adaptive immune response", "id": "GO:0002250", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002250", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z251", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z251", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z251" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 300, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 257, "end_pos": 259 }, { "start_pos": 271, "end_pos": 273 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z272-1", "uniprot_ac": "A0A8M6Z272", "uniprot_id": "A0A8M6Z272_DANRE", "mass": { "chemical_mass": 47602.0, "monoisotopic_mass": 47602.0 }, "refseq": { "ac": "XP_017207132", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207132" }, "gene_names": [ { "name": "im:7148213", "type": "recommended", "evidence": [ { "id": "A0A8M6Z272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z272" } ] }, { "name": "zgc:113176", "type": "recommended", "evidence": [ { "id": "A0A8M6Z272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z272" } ] }, { "name": "im:7148213", "type": "synonym", "evidence": [ { "id": "XP_017207132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207132" }, { "id": "A0A8M6Z272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z272" } ] }, { "name": "zgc:113176", "type": "synonym", "evidence": [ { "id": "XP_017207132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207132" }, { "id": "A0A8M6Z272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z272" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z272", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z272/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017207132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207132" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017207132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207132" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z272", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z272" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "im:7148213", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z272", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050327-60", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-60", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z272", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z272", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000040487", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000040487", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00084", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00084", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00086", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00086", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "554708", "url": "https://www.ncbi.nlm.nih.gov/gene/554708", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:554708", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:554708", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z272", "url": "https://www.orthodb.org/?gene=A0A8M6Z272", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "X1WCN5", "url": "https://www.orthodb.org/?gene=X1WCN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46304:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46304:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02946", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02946", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017207132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207132", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z272", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z272", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z272-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z272-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HN41", "url": "https://www.uniprot.org/uniprotkb/A0AC58HN41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HN41-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HN41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HN51", "url": "https://www.uniprot.org/uniprotkb/A0AC58HN51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HN51-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HN51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X1WCN5", "url": "https://www.uniprot.org/uniprotkb/X1WCN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X1WCN5-1", "url": "https://www.uniprot.org/uniprotkb/X1WCN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050327-60", "url": "https://zfin.org/ZDB-GENE-050327-60", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MICNIFFVTDLLLTSFFFFVFIQQERTHINPEQRETLISFFQEGMKHVGSPLITRAASAMGLDTSVIENWIGNYKRSLILKDSSEPRPSKVKAHIRELSPYNLFCRDVFRNKGTMNDIKGRWATLGEDEKQKYIEEAAALRAHGQPLSPEMRDARIKMHLKKLKLEVSKLEELGVETAILSFDRQKSSLEVYELSSKGATDFLDSTGTVNNFAPHFKASSSAITPSTKDQVSVLVGKVQDLFNQKYKEAGGTGRLPYQSLMNQGMTIKVAGLPNSLTLRKPSFYGRNQLEAILKAAEGISFEINGAQCNPTNMAEGTSEHMAAEGTPQLKEESIETPVAIMMTGDKGAQQMEDESSETATTVAIMMTEDTDGGMLCCVCSVHKKENASKKWRSWSQCTMCQSWSHTACGFEKNLCFHCQCENAMQSS", "length": 427, "header": "tr|A0A8M6Z272-1|A0A8M6Z272_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=im:7148213 PE=4 SV=1 CANONICAL=A0A8M6Z272-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z272-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z272/entry#A0A8M6Z272-1", "sequence": { "sequence": "MICNIFFVTDLLLTSFFFFVFIQQERTHINPEQRETLISFFQEGMKHVGSPLITRAASAMGLDTSVIENWIGNYKRSLILKDSSEPRPSKVKAHIRELSPYNLFCRDVFRNKGTMNDIKGRWATLGEDEKQKYIEEAAALRAHGQPLSPEMRDARIKMHLKKLKLEVSKLEELGVETAILSFDRQKSSLEVYELSSKGATDFLDSTGTVNNFAPHFKASSSAITPSTKDQVSVLVGKVQDLFNQKYKEAGGTGRLPYQSLMNQGMTIKVAGLPNSLTLRKPSFYGRNQLEAILKAAEGISFEINGAQCNPTNMAEGTSEHMAAEGTPQLKEESIETPVAIMMTGDKGAQQMEDESSETATTVAIMMTEDTDGGMLCCVCSVHKKENASKKWRSWSQCTMCQSWSHTACGFEKNLCFHCQCENAMQSS", "length": 427, "header": "tr|A0A8M6Z272-1|A0A8M6Z272_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=im:7148213 PE=4 SV=1 CANONICAL=A0A8M6Z272-1" }, "locus": {} }, { "isoform_ac": "A0AC58HN41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z272/entry#A0AC58HN41-1", "sequence": { "sequence": "MKHVGSPLITRAASAMGLDTSVIENWIGNYKRSLILKDSSEPRPSKVKAHIRELSPYNLFCRDVFRNKGTMNDIKGRWATLGEDEKQKYIEEAAALRAHGQPLSPEMRDARIKMHLKKLKLEVSKLEELGVETAILSFDRQKSSLEVYELSSKGATDFLDSTGTVNNFAPHFKASSSAITPSTKDQVSVLVGKVQDLFNQKYKEAGGTGRLPYQSLMNQGMTIKVAGLPNSLTLRKPSFYGRNQLEAILKAAEGISFEINGAQCNPTNMAEGTSEHMAAEGTPQLKEESIETPVAIMMTGDKGAQQMEDESSETATTVAIMMTEDTDGGMLCCVCSVHKKENASKKWRSWSQCTMCQSWSHTACGFEKNLCFHCQCENAMQSS", "length": 383, "header": "tr|A0AC58HN41-1|A0AC58HN41_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=zgc:113176 PE=4 SV=1 CANONICAL=A0A8M6Z272-1" }, "locus": {} }, { "isoform_ac": "A0AC58HN51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z272/entry#A0AC58HN51-1", "sequence": { "sequence": 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"MAKRERTHINPEQRETLISFFQEGMKHVGSPLITRAASAMGLDTSVIENWIGNYKRSLILKDSSEPRPSKVKAHIRELSPYNLFCRDVFRNKGTMNDIKGRWATLGEDEKQKYIEEAAALRAHGQPLSPEMRDARIKMHLKKLKLEVSKLEELGVETAILSFDRQKSSLEVYELSSKGATDFLDSTGTVNNFAPHFKASSSAITPSTKDQVSVLVGKVQDLFNQKYKEAGGTGRLPYQSLMNQGMTIKVAGLPNSLTLRKPSFYGRNQLEAILKAAEGISFEINGAQCNPTNMAEGTSEHMAAEGTPQLKEESIETPVAIMMTGDKGAQQMEDESSETATTVAIMMTEDTDGGMLCCVCSVHKKENASKKWRSWSQCTMCQSWSHTACGFEKNLCFHCQCENAMQSS", "length": 407, "header": "tr|X1WCN5-1|A0A8M6Z272_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=im:7148213 PE=4 SV=1 CANONICAL=A0A8M6Z272-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. 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"Protein" ] }, { "id": "A0A8M9PNW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PS66", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PS66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS66-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HZQ6", "url": "https://www.uniprot.org/uniprotkb/A0AC58HZQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HZQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HZQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HZT6", "url": "https://www.uniprot.org/uniprotkb/A0AC58HZT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HZT6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HZT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-512", "url": "https://zfin.org/ZDB-GENE-070912-512", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNRQREIEETLSINTDKIEEAQKEFKDPKGAHKDTNESTGRNSESIKGLKRKKVVAQNQLKKIPKSPVKKQSQTKKSISSNISSKEATPSSFPSSPSHGSPKPEDAEDGPEEVSASRTVKVEQEEISTSEPQALSHKGAAAEPCVAEPVQTESWCGDSCNKSTQSPSHTSAPLEVLLKAMEPDFIDFTERKNSSPIGHLGKSASNPVTYSDYAVAMPAVNFNIQSQNSFMQPFNAAKQYYSSVASTGQHITQPYMSGNRQQEKPGVQKSYSVGPSLTLMHAPVPSGSGGFPQSQPPVVQTCQSLSATVPNSIQVPVTPGYNPVQMTTVVNFGASQVSDISAKDQKPKKQGKYVCEYCKRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHAIKLGLVKDSGSGSLSQESDKGLATHSDVDESGDSDEESSAADLDADSSQSSLTALSESSLQSASMIQGSQAESEHSLVFENLKPSATQRGCEPKVTAALPKVVVHPVNVSPLRADSPRVTDSAPEQATAQRQRDFQPTNLRSNVTVLSSLKEVDCTSPPQDSVSDDEDQHCKSPLGGSHAQLQRQQATDYSQQAQVKCLLSPRSLGSTDSGYFSRSESADQAMSPPSPFVKITPPGDTDITKTPHIPPCPVVAAVMHVATIEKPRVPSGQMRPPLETKALSLEERISKLISDNEAVVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPPVRRSSSNSDIPKSPFTPTDKSKQVFLLSVPSQYPAMECLPITRSNSMPTTPGQSALFPNVTTQPHQLRICQSFDDKISSLNDDVFSSAPSTPNPAVHPRTLVRQIAVEDLSTNDGHVLIQVHSMDESHHGPSITHELRSKSFEHATERNRKPQQNKGTMYECETCRNRYRKLENFENHKKFYCSELHGPKNKPMHARETEHEVFGRGIQQPLLNRNAVITGNVEQPLMLRKRRKIKSVGDDDDQSPTETTPPCSRSFDSSQSSTGSIGRTNSHHTQSLGNSAILGQIQIIARAGELQESRLSPIREAQISTPCKERGDLQRQGSGTSVIRHTNSLSRPNSFETSESIDRSSPVDPVEKETKISVKSHTETAVSSSQSYHDRMSTPKCPSQTHEKQSFAIVGDVPPVQQSRLVRQSNIQVPEILVTEEPDRDHETQVVESTEKPAETFSWPQRSESLSKLPTEKLPPKKKRIRLAQMEHSSGESSFESSLSRSLSRDSSLSRCSSISASFDRDDPPRSDSPSRADSVGKPPETQGVPVANNTLGVPGIMRRSTSEQISYTQSSVEISCDYRSKSFDCSSMSPSRPLSPMQTALPKTTQCPPSTLVPLIERRRGPLVRQMSLKIAPEPQIAVKQTTPIQRVPFTNECSGSQPRSVNLNTSALAQCFAVHSGEVSLPKNEQVVQSINLGGKTEQPQVHGLPHPWHQTSRVVAGHVQPLVHMVGGQTDIKKSSDEKNKIFIPKYQMNCPVLKTGQTYSLAGVQGTQIPLPVITIPIANEIKGSHSNDGMQNVYVAQSSYQAVLNKPSIVQPSNAQVDTASHKVPVSAPVPQILITHEHTLASASAVSKVSFPIAPSVNRDSKIGPEIQAQKQPGSVAVQMKNNMKTTDQIQNTEQSILSLGSLHCMQKLASANLCPQESTASSKRMLSPANSLDIAMEKTQKRAKDEHGAACLTDGRSLNYLNSKMSEITRQRKLMLVRQVCTTEPVDSPIETDAPEQLPETLDTEKNTQKPIPQVTTTEVSEQEMESRTPTTTPPARSLPGVQGYPMLENSTLKPQEKPEEQRWSPSKSPLRPPSFQGQVKLASSVSVVNTRDSHRLSFPSLKTATTFTWCFLMKRKPLHVQQMDQRISAYSAWVVNPNNPNPLGLPTKVVMSLFDSKQTSKKIHYTQAKTTTLKSDILTYSGKLKDVLPKVLIQQRSVPSENSGKTKPDTQPVNQKESDRDTSKSEPQRVKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHSDIRPFHCTHCNFSFKTKGNLTKHMKSKAHSKKCMEMGVAVGIIEDQDAEDSGDRGRAGSADRQDSDGDDSDGPDDEDNEGEEEDEEDSQAESGLSATPSVSASPQHFSANQADLAPSSLLAQMSISPNPSPALQSQPPPTSDSQTSDTESVAMTSPVSLVRQMSISASCSSPGPNPTSFTSHPTPASESHTSDTDSVHMMSPVSPCRQMSIDYPDFDVPPSPPVSGKGAKLGQDGVSSTISQPASECNANVDRGTQTSSDPLQGSLHFPHAGPLHEPRIGATTHLFSHLPLHSQQPPRSPYSMVPVGGIQLVPAGLAAYSTFVPIQAGPVQLTIPALSVIHRQTGSPLSAPNTSPRPDCSPTQPLVVQEPVSSVLPCFPLGQVAGLQTLGAHQTALQPVGLETLSVVGLANSTQLVPQQSLPLNATLGVQVLAASPAPQCSTASPAQIPGLQILNIALPALIPSLSPLSALSPLPATQDKPRSPEGVASVTLPAQVAGSPPAPLPSASPPTANPGDAAVNAKPCMEVRKVSQNNPSVGSRDTGGAEKTTGMVEKSKAPPQPPSPCSPSLSNERGCNVAHKGSAGEACEVKPRQPVSRQPVTDDYNEASSDDEDRLVIAT", "length": 2636, "header": "tr|A0A8M9PBC6-1|A0A8M9PBC6_DANRE Isoform 1 of Zinc finger protein 40 OS=Danio rerio OX=7955 GN=hivep1 PE=4 SV=1 CANONICAL=A0A8M9PBC6-1" }, "isoforms": [ { "isoform_ac": "A0A8M3AV90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6/entry#A0A8M3AV90-1", "sequence": { "sequence": "MEPDFIDFTERKNSSPIGHLGKSASNPVTYSDYAVAMPAVNFNIQSQNSFMQPFNAAKQYYSSVASTGQHITQPYMSGNRQQEKPGVQKSYSVGPSLTLMHAPVPSGSGGFPQSQPPVVQTCQSLSATVPNSIQVPVTPGYNPVQMTTVVNFGASQVSDISAKDQKPKKQGKYVCEYCKRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHAIKLGLVKDSGSGSLSQESDKGLATHSDVDESGDSDEESSAADLDADSSQSSLTALSESSLQSASMIQGSQAESEHSLVFENLKPSATQRGCEPKVTAALPKVVVHPVNVSPLRADSPRVTDSAPEQATAQRQRDFQPTNLRSNVTVLSSLKEVDCTSPPQDSVSDDEDQHCKSPLGGSHAQLQRQQATDYSQQAQVKCLLSPRSLGSTDSGYFSRSESADQAMSPPSPFVKITPPGDTDITKTPHIPPCPVVAAVMHVATIEKPRVPSGQMRPPLETKALSLEERISKLISDNEAVVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPPVRRSSSNSDIPKSPFTPTDKSKQVFLLSVPSQYPAMECLPITRSNSMPTTPGQSALFPNVTTQPHQLRICQSFDDKISSLNDDVFSSAPSTPNPAVHPRTLVRQIAVEDLSTNDGHVLIQVHSMDESHHGPSITHELRSKSFEHATERNRKPQQNKGTMYECETCRNRYRKLENFENHKKFYCSELHGPKNKPMHARETEHEVFGRGIQQPLLNRNAVITGNVEQPLMLRKRRKIKSVGDDDDQSPTETTPPCSRSFDSSQSSTGSIGRTNSHHTQSLGNSAILGQIQIIARAGELQESRLSPIREAQISTPCKERGDLQRQGSGTSVIRHTNSLSRPNSFETSESIDRSSPVDPVEKETKISVKSHTETAVSSSQSYHDRMSTPKCPSQTHEKQSFAIVGDVPPVQQSRLVRQSNIQVPEILVTEEPDRDHETQVVESTEKPAETFSWPQRSESLSKLPTEKLPPKKKRIRLAQMEHSSGESSFESSLSRSLSRDSSLSRCSSISASFDRDDPPRSDSPSRADSVGKPPETQGVPVANNTLGVPGIMRRSTSEQISYTQSSVEISCDYRSKSFDCSSMSPSRPLSPMQTALPKTTQCPPSTLVPLIERRRGPLVRQMSLKIAPEPQIAVKQTTPIQRVPFTNECSGSQPRSVNLNTSALAQCFAVHSGEVSLPKNEQVVQSINLGGKTEQPQVHGLPHPWHQTSRVVAGHVQPLVHMVGGQTDIKKSSDEKNKIFIPKYQMNCPVLKTGQTYSLAGVQGTQIPLPVITIPIANEIKGSHSNDGMQNVYVAQSSYQAVLNKPSIVQPSNAQVDTASHKVPVSAPVPQILITHEHTLASASAVSKVSFPIAPSVNRDSKIGPEIQAQKQPGSVAVQMKNNMKTTDQIQNTEQSILSLGSLHCMQKLASANLCPQESTASSKRMLSPANSLDIAMEKTQKRAKDEHGAACLTDGRSLNYLNSKMSEITRQRKLMLVRQVCTTEPVDSPIETDAPEQLPETLDTEKNTQKPIPQVTTTEVSEQEMESRTPTTTPPARSLPGVQGYPMLENSTLKPQEKPEEQRWSPSKSPLRPPSFQGQVKLASSVSVVNTRDSHRLSFPSLKTATTFTWCFLMKRKPLHVQQMDQRISAYSAWVVNPNNPNPLGLPTKVVMSLFDSKQTSKKIHYTQAKTTTLKSDILTYSGKLKDVLPKVLIQQRSVPSENSGKTKPDTQPVNQKESDRDTSKSEPQRVKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHSDIRPFHCTHCNFSFKTKGNLTKHMKSKAHSKKCMEMGVAVGIIEDQDAEDSGDRGRAGSADRQDSDGDDSDGPDDEDNEGEEEDEEDSQAESGLSATPSVSASPQHFSANQADLAPSSLLAQMSISPNPSPALQSQPPPTSDSQTSDTESVAMTSPVSLVRQMSISASCSSPGPNPTSFTSHPTPASESHTSDTDSVHMMSPVSPCRQMSIDYPDFDVPPSPPVSGKGAKLGQDGVSSTISQPASECNANVDRGTQTSSDPLQGSLHFPHAGPLHEPRIGATTHLFSHLPLHSQQPPRSPYSMVPVGGIQLVPAGLAAYSTFVPIQAGPVQLTIPALSVIHRQTGSPLSAPNTSPRPDCSPTQPLVVQEPVSSVLPCFPLGQVAGLQTLGAHQTALQPVGLETLSVVGLANSTQLVPQQSLPLNATLGVQVLAASPAPQCSTASPAQIPGLQILNIALPALIPSLSPLSALSPLPATQDKPRSPEGVASVTLPAQVAGSPPAPLPSASPPTANPGDAAVNAKPCMEVRKVSQNNPSVGSRDTGGAEKTTGMVEKSKAPPQPPSPCSPSLSNERGCNVAHKGSAGEACEVKPRQPVSRQPVTDDYNEASSDDEDRLVIAT", "length": 2457, "header": "tr|A0A8M3AV90-1|A0A8M9PBC6_DANRE Computationally mapped isoform of Zinc finger protein 40 OS=Danio rerio OX=7955 GN=hivep1 PE=4 SV=1 CANONICAL=A0A8M9PBC6-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PBC6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6/entry#A0A8M9PBC6-1", "sequence": { "sequence": "MNRQREIEETLSINTDKIEEAQKEFKDPKGAHKDTNESTGRNSESIKGLKRKKVVAQNQLKKIPKSPVKKQSQTKKSISSNISSKEATPSSFPSSPSHGSPKPEDAEDGPEEVSASRTVKVEQEEISTSEPQALSHKGAAAEPCVAEPVQTESWCGDSCNKSTQSPSHTSAPLEVLLKAMEPDFIDFTERKNSSPIGHLGKSASNPVTYSDYAVAMPAVNFNIQSQNSFMQPFNAAKQYYSSVASTGQHITQPYMSGNRQQEKPGVQKSYSVGPSLTLMHAPVPSGSGGFPQSQPPVVQTCQSLSATVPNSIQVPVTPGYNPVQMTTVVNFGASQVSDISAKDQKPKKQGKYVCEYCKRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHAIKLGLVKDSGSGSLSQESDKGLATHSDVDESGDSDEESSAADLDADSSQSSLTALSESSLQSASMIQGSQAESEHSLVFENLKPSATQRGCEPKVTAALPKVVVHPVNVSPLRADSPRVTDSAPEQATAQRQRDFQPTNLRSNVTVLSSLKEVDCTSPPQDSVSDDEDQHCKSPLGGSHAQLQRQQATDYSQQAQVKCLLSPRSLGSTDSGYFSRSESADQAMSPPSPFVKITPPGDTDITKTPHIPPCPVVAAVMHVATIEKPRVPSGQMRPPLETKALSLEERISKLISDNEAVVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPPVRRSSSNSDIPKSPFTPTDKSKQVFLLSVPSQYPAMECLPITRSNSMPTTPGQSALFPNVTTQPHQLRICQSFDDKISSLNDDVFSSAPSTPNPAVHPRTLVRQIAVEDLSTNDGHVLIQVHSMDESHHGPSITHELRSKSFEHATERNRKPQQNKGTMYECETCRNRYRKLENFENHKKFYCSELHGPKNKPMHARETEHEVFGRGIQQPLLNRNAVITGNVEQPLMLRKRRKIKSVGDDDDQSPTETTPPCSRSFDSSQSSTGSIGRTNSHHTQSLGNSAILGQIQIIARAGELQESRLSPIREAQISTPCKERGDLQRQGSGTSVIRHTNSLSRPNSFETSESIDRSSPVDPVEKETKISVKSHTETAVSSSQSYHDRMSTPKCPSQTHEKQSFAIVGDVPPVQQSRLVRQSNIQVPEILVTEEPDRDHETQVVESTEKPAETFSWPQRSESLSKLPTEKLPPKKKRIRLAQMEHSSGESSFESSLSRSLSRDSSLSRCSSISASFDRDDPPRSDSPSRADSVGKPPETQGVPVANNTLGVPGIMRRSTSEQISYTQSSVEISCDYRSKSFDCSSMSPSRPLSPMQTALPKTTQCPPSTLVPLIERRRGPLVRQMSLKIAPEPQIAVKQTTPIQRVPFTNECSGSQPRSVNLNTSALAQCFAVHSGEVSLPKNEQVVQSINLGGKTEQPQVHGLPHPWHQTSRVVAGHVQPLVHMVGGQTDIKKSSDEKNKIFIPKYQMNCPVLKTGQTYSLAGVQGTQIPLPVITIPIANEIKGSHSNDGMQNVYVAQSSYQAVLNKPSIVQPSNAQVDTASHKVPVSAPVPQILITHEHTLASASAVSKVSFPIAPSVNRDSKIGPEIQAQKQPGSVAVQMKNNMKTTDQIQNTEQSILSLGSLHCMQKLASANLCPQESTASSKRMLSPANSLDIAMEKTQKRAKDEHGAACLTDGRSLNYLNSKMSEITRQRKLMLVRQVCTTEPVDSPIETDAPEQLPETLDTEKNTQKPIPQVTTTEVSEQEMESRTPTTTPPARSLPGVQGYPMLENSTLKPQEKPEEQRWSPSKSPLRPPSFQGQVKLASSVSVVNTRDSHRLSFPSLKTATTFTWCFLMKRKPLHVQQMDQRISAYSAWVVNPNNPNPLGLPTKVVMSLFDSKQTSKKIHYTQAKTTTLKSDILTYSGKLKDVLPKVLIQQRSVPSENSGKTKPDTQPVNQKESDRDTSKSEPQRVKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHSDIRPFHCTHCNFSFKTKGNLTKHMKSKAHSKKCMEMGVAVGIIEDQDAEDSGDRGRAGSADRQDSDGDDSDGPDDEDNEGEEEDEEDSQAESGLSATPSVSASPQHFSANQADLAPSSLLAQMSISPNPSPALQSQPPPTSDSQTSDTESVAMTSPVSLVRQMSISASCSSPGPNPTSFTSHPTPASESHTSDTDSVHMMSPVSPCRQMSIDYPDFDVPPSPPVSGKGAKLGQDGVSSTISQPASECNANVDRGTQTSSDPLQGSLHFPHAGPLHEPRIGATTHLFSHLPLHSQQPPRSPYSMVPVGGIQLVPAGLAAYSTFVPIQAGPVQLTIPALSVIHRQTGSPLSAPNTSPRPDCSPTQPLVVQEPVSSVLPCFPLGQVAGLQTLGAHQTALQPVGLETLSVVGLANSTQLVPQQSLPLNATLGVQVLAASPAPQCSTASPAQIPGLQILNIALPALIPSLSPLSALSPLPATQDKPRSPEGVASVTLPAQVAGSPPAPLPSASPPTANPGDAAVNAKPCMEVRKVSQNNPSVGSRDTGGAEKTTGMVEKSKAPPQPPSPCSPSLSNERGCNVAHKGSAGEACEVKPRQPVSRQPVTDDYNEASSDDEDRLVIAT", "length": 2636, "header": "tr|A0A8M9PBC6-1|A0A8M9PBC6_DANRE Isoform 1 of Zinc finger protein 40 OS=Danio rerio OX=7955 GN=hivep1 PE=4 SV=1 CANONICAL=A0A8M9PBC6-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PNW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6/entry#A0A8M9PNW6-1", "sequence": { "sequence": "MNRQREIEETLSINTDKIEEAQKEFKDPKGAHKDTNESTGRNSESIKGLKRKKVVAQNQLKKIPKSPVKKQSQTKKSISSNISSKEATPSSFPSSPSHGSPKPEDAEDGPEEVSASRTVKVEQEEISTSEPQALSHKGAAAEPCVAEPVQTESWCGDSCNKSTQSPSHTSAPLEVLLKAMEPDFIDFTERKNSSPIGHLGKSASNPVTYSDYAVAMPAVNFNIQSQNSFMQPFNAAKQYYSSVASTGQHITQPYMSGNRQQEKPGVQKSYSVGPSLTLMHAPVPSGSGGFPQSQPPVVQTCQSLSATVPNSIQVPVTPGYNPVQMTTVVNFGASQVSDISAKDQKPKKQGKYVCEYCKRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHAIKLGLVKDSGSGSLSQESDKGLATHSDVDESGDSDEESSAADLDADSSQSSLTALSESSLQSASMIQGSQAESEHSLVFENLKPSATQRGCEPKVTAALPKVVVHPVNVSPLRADSPRVTDSAPEQATAQRQRDFQPTNLRSNVTVLSSLKEVDCTSPPQDSVSDDEDQHCKSPLGGSHAQLQRQQATDYSQQAQVKCLLSPRSLGSTDSGYFSRSESADQAMSPPSPFVKITPPGDTDITKTPHIPPCPVVAAVMHVATIEKPRVPSGQMRPPLETKALSLEERISKLISDNEAVVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPPVRRSSSNSDIPKSPFTPTDKSKQVFLLSVPSQYPAMECLPITRSNSMPTTPGQSALFPNVTTQPHQLRICQSFDDKISSLNDDVFSSAPSTPNPAVHPRTLVRQIAVEDLSTNDGHVLIQVHSMDESHHGPSITHELRSKSFEHATERNRKPQQNKGTMYECETCRNRYRKLENFENHKKFYCSELHGPKNKPMHARETEHEVFGRGIQQPLLNRNAVITGNVEQPLMLRKRRKIKSVGDDDDQSPTETTPPCSRSFDSSQSSTGSIGRTNSHHTQSLGNSAILGQIQIIARAGELQESRLSPIREAQISTPCKERGDLQRQGSGTSVIRHTNSLSRPNSFETSESIDRSSPVDPVEKETKISVKSHTETAVSSSQSYHDRMSTPKCPSQTHEKQSFAIVGDVPPVQQSRLVRQSNIQVPEILVTEEPDRDHETQVVESTEKPAETFSWPQRSESLSKLPTEKLPPKKKRIRLAQMEHSSGESSFESSLSRSLSRDSSLSRCSSISASFDRDDPPRSDSPSRADSVGKPPETQGVPVANNTLGVPGIMRRSTSEQISYTQSSVEISCDYRSKSFDCSSMSPSRPLSPMQTALPKTTQCPPSTLVPLIERRRGPLVRQMSLKIAPEPQIAVKQTTPIQRVPFTNECSGSQPRSVNLNTSALAQCFAVHSGEVSLPKNEQVVQSINLGGKTEQPQVHGLPHPWHQTSRVVAGHVQPLVHMVGGQTDIKKSSDEKNKIFIPKYQMNCPVLKTGQTYSLAGVQGTQIPLPVITIPIANEIKGSHSNDGMQNVYVAQSSYQAVLNKPSIVQPSNAQVDTASHKVPVSAPVPQILITHEHTLASASAVSKVSFPIAPSVNRDSKIGPEIQAQKQPGSVAVQMKNNMKTTDQIQNTEQSILSLGSLHCMQKLASANLCPQESTASSKRMLSPANSLDIAMEKTQKRAKDEHGAACLTDGRSLNYLNSKMSEITRQRKLMLVRQVCTTEPVDSPIETDAPEQLPETLDTEKNTQKPIPQVTTTEVSEQEMESRTPTTTPPARSLPGVQGYPMLENSTLKPQEKPEEQRWSPSKSPLRPPSFQGQVKLASSVSVVNTRDSHRLSFPSLKTATTFTWCFLMKRKPLHVQQMDQRISAYSAWVVNPNNPNPLGLPTKVVMSLFDSKQTSKKIHYTQAKTTTLKSDILTYSGKLKDVLPKVLIQQRSVPSENSGKTKPDTQPVNQKESDRDTSKSEPQRVKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHSDIRPFHCTHCNFSFKTKGNLTKHMKSKAHSKKCMEMGVAVGIIEDQDAEDSGDRGRAGSADRQDSDGDDSDGPDDEDNEGEEEDEEDSQAESGLSATPSVSASPQHFSANQADLAPSSLLAQMSISPNPSPALQSQPPPTSDSQTSDTESVAMTSPVSLVRQMSISASCSSPGPNPTSFTSHPTPASESHTSDTDSVHMMSPVSPCRQMSIDYPDFDVPPSPPVSGKGAKLGQVRPVSSPSLSFPSCIPSSLHVHLTPYQYQTSYAFPCLESRMPGTSAKLL", "length": 2299, "header": "tr|A0A8M9PNW6-1|A0A8M9PNW6_DANRE Computationally mapped isoform of Zinc finger protein 40 OS=Danio rerio OX=7955 GN=hivep1 PE=4 SV=1 CANONICAL=A0A8M9PBC6-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PS66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6/entry#A0A8M9PS66-1", "sequence": { "sequence": "MPRTKQNNPKNLKDKIEEAQKEFKDPKGAHKDTNESTGRNSESIKGLKRKKVVAQNQLKKIPKSPVKKQSQTKKSISSNISSKEATPSSFPSSPSHGSPKPEDAEDGPEEVSASRTVKVEQEEISTSEPQALSHKGAAAEPCVAEPVQTESWCGDSCNKSTQSPSHTSAPLEVLLKAMEPDFIDFTERKNSSPIGHLGKSASNPVTYSDYAVAMPAVNFNIQSQNSFMQPFNAAKQYYSSVASTGQHITQPYMSGNRQQEKPGVQKSYSVGPSLTLMHAPVPSGSGGFPQSQPPVVQTCQSLSATVPNSIQVPVTPGYNPVQMTTVVNFGASQVSDISAKDQKPKKQGKYVCEYCKRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHAIKLGLVKDSGSGSLSQESDKGLATHSDVDESGDSDEESSAADLDADSSQSSLTALSESSLQSASMIQGSQAESEHSLVFENLKPSATQRGCEPKVTAALPKVVVHPVNVSPLRADSPRVTDSAPEQATAQRQRDFQPTNLRSNVTVLSSLKEVDCTSPPQDSVSDDEDQHCKSPLGGSHAQLQRQQATDYSQQAQVKCLLSPRSLGSTDSGYFSRSESADQAMSPPSPFVKITPPGDTDITKTPHIPPCPVVAAVMHVATIEKPRVPSGQMRPPLETKALSLEERISKLISDNEAVVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPPVRRSSSNSDIPKSPFTPTDKSKQVFLLSVPSQYPAMECLPITRSNSMPTTPGQSALFPNVTTQPHQLRICQSFDDKISSLNDDVFSSAPSTPNPAVHPRTLVRQIAVEDLSTNDGHVLIQVHSMDESHHGPSITHELRSKSFEHATERNRKPQQNKGTMYECETCRNRYRKLENFENHKKFYCSELHGPKNKPMHARETEHEVFGRGIQQPLLNRNAVITGNVEQPLMLRKRRKIKSVGDDDDQSPTETTPPCSRSFDSSQSSTGSIGRTNSHHTQSLGNSAILGQIQIIARAGELQESRLSPIREAQISTPCKERGDLQRQGSGTSVIRHTNSLSRPNSFETSESIDRSSPVDPVEKETKISVKSHTETAVSSSQSYHDRMSTPKCPSQTHEKQSFAIVGDVPPVQQSRLVRQSNIQVPEILVTEEPDRDHETQVVESTEKPAETFSWPQRSESLSKLPTEKLPPKKKRIRLAQMEHSSGESSFESSLSRSLSRDSSLSRCSSISASFDRDDPPRSDSPSRADSVGKPPETQGVPVANNTLGVPGIMRRSTSEQISYTQSSVEISCDYRSKSFDCSSMSPSRPLSPMQTALPKTTQCPPSTLVPLIERRRGPLVRQMSLKIAPEPQIAVKQTTPIQRVPFTNECSGSQPRSVNLNTSALAQCFAVHSGEVSLPKNEQVVQSINLGGKTEQPQVHGLPHPWHQTSRVVAGHVQPLVHMVGGQTDIKKSSDEKNKIFIPKYQMNCPVLKTGQTYSLAGVQGTQIPLPVITIPIANEIKGSHSNDGMQNVYVAQSSYQAVLNKPSIVQPSNAQVDTASHKVPVSAPVPQILITHEHTLASASAVSKVSFPIAPSVNRDSKIGPEIQAQKQPGSVAVQMKNNMKTTDQIQNTEQSILSLGSLHCMQKLASANLCPQESTASSKRMLSPANSLDIAMEKTQKRAKDEHGAACLTDGRSLNYLNSKMSEITRQRKLMLVRQVCTTEPVDSPIETDAPEQLPETLDTEKNTQKPIPQVTTTEVSEQEMESRTPTTTPPARSLPGVQGYPMLENSTLKPQEKPEEQRWSPSKSPLRPPSFQGQVKLASSVSVVNTRDSHRLSFPSLKTATTFTWCFLMKRKPLHVQQMDQRISAYSAWVVNPNNPNPLGLPTKVVMSLFDSKQTSKKIHYTQAKTTTLKSDILTYSGKLKDVLPKVLIQQRSVPSENSGKTKPDTQPVNQKESDRDTSKSEPQRVKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHSDIRPFHCTHCNFSFKTKGNLTKHMKSKAHSKKCMEMGVAVGIIEDQDAEDSGDRGRAGSADRQDSDGDDSDGPDDEDNEGEEEDEEDSQAESGLSATPSVSASPQHFSANQADLAPSSLLAQMSISPNPSPALQSQPPPTSDSQTSDTESVAMTSPVSLVRQMSISASCSSPGPNPTSFTSHPTPASESHTSDTDSVHMMSPVSPCRQMSIDYPDFDVPPSPPVSGKGAKLGQDGVSSTISQPASECNANVDRGTQTSSDPLQGSLHFPHAGPLHEPRIGATTHLFSHLPLHSQQPPRSPYSMVPVGGIQLVPAGLAAYSTFVPIQAGPVQLTIPALSVIHRQTGSPLSAPNTSPRPDCSPTQPLVVQEPVSSVLPCFPLGQVAGLQTLGAHQTALQPVGLETLSVVGLANSTQLVPQQSLPLNATLGVQVLAASPAPQCSTASPAQIPGLQILNIALPALIPSLSPLSALSPLPATQDKPRSPEGVASVTLPAQVAGSPPAPLPSASPPTANPGDAAVNAKPCMEVRKVSQNNPSVGSRDTGGAEKTTGMVEKSKAPPQPPSPCSPSLSNERGCNVAHKGSAGEACEVKPRQPVSRQPVTDDYNEASSDDEDRLVIAT", "length": 2634, "header": "tr|A0A8M9PS66-1|A0A8M9PBC6_DANRE Computationally mapped isoform of Zinc finger protein 40 OS=Danio rerio OX=7955 GN=hivep1 PE=4 SV=1 CANONICAL=A0A8M9PBC6-1" }, "locus": {} }, { "isoform_ac": "A0AC58HZQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6/entry#A0AC58HZQ6-1", "sequence": { "sequence": "MEPDFIDFTERKNSSPIGHLGKSASNPVTYSDYAVAMPAVNFNIQSQNSFMQPFNAAKQYYSSVASTGQHITQPYMSGNRQQEKPGVQKSYSVGPSLTLMHAPVPSGSGGFPQSQPPVVQTCQSLSATVPNSIQVPVTPGYNPVQMTTVVNFGASQVSDISAKDQKPKKQGKYVCEYCKRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHAIKLGLVKDSGSGSLSQESDKGLATHSDVDESGDSDEESSAADLDADSSQSSLTALSESSLQSASMIQGSQAESEHSLVFENLKPSATQRGCEPKVTAALPKVVVHPVNVSPLRADSPRVTDSAPEQATAQRQRDFQPTNLRSNVTVLSSLKEVDCTSPPQDSVSDDEDQHCKSPLGGSHAQLQRQQATDYSQQAQVKCLLSPRSLGSTDSGYFSRSESADQAMSPPSPFVKITPPGDTDITKTPHIPPCPVVAAVMHVATIEKPRVPSGQMRPPLETKALSLEERISKLISDNEAVVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPPVRRSSSNSDIPKSPFTPTDKSKQVFLLSVPSQYPAMECLPITRSNSMPTTPGQSALFPNVTTQPHQLRICQSFDDKISSLNDDVFSSAPSTPNPAVHPRTLVRQIAVEDLSTNDGHVLIQVHSMDESHHGPSITHELRSKSFEHATERNRKPQQNKGTMYECETCRNRYRKLENFENHKKFYCSELHGPKNKPMHARETEHEVFGRGIQQPLLNRNAVITGNVEQPLMLRKRRKIKSVGDDDDQSPTETTPPCSRSFDSSQSSTGSIGRTNSHHTQSLGNSAILGQIQIIARAGELQESRLSPIREAQISTPCKERGDLQRQGSGTSVIRHTNSLSRPNSFETSESIDRSSPVDPVEKETKISVKSHTETAVSSSQSYHDRMSTPKCPSQTHEKQSFAIVGDVPPVQQSRLVRQSNIQVPEILVTEEPDRDHETQVVESTEKPAETFSWPQRSESLSKLPTEKLPPKKKRIRLAQMEHSSGESSFESSLSRSLSRDSSLSRCSSISASFDRDDPPRSDSPSRADSVGKPPETQGVPVANNTLGVPGIMRRSTSEQISYTQSSVEISCDYRSKSFDCSSMSPSRPLSPMQTALPKTTQCPPSTLVPLIERRRGPLVRQMSLKIAPEPQIAVKQTTPIQRVPFTNECSGSQPRSVNLNTSALAQCFAVHSGEVSLPKNEQVVQSINLGGKTEQPQVHGLPHPWHQTSRVVAGHVQPLVHMVGGQTDIKKSSDEKNKIFIPKYQMNCPVLKTGQTYSLAGVQGTQIPLPVITIPIANEIKGSHSNDGMQNVYVAQSSYQAVLNKPSIVQPSNAQVDTASHKVPVSAPVPQILITHEHTLASASAVSKVSFPIAPSVNRDSKIGPEIQAQKQPGSVAVQMKNNMKTTDQIQNTEQSILSLGSLHCMQKLASANLCPQESTASSKRMLSPANSLDIAMEKTQKRAKDEHGAACLTDGRSLNYLNSKMSEITRQRKLMLVRQVCTTEPVDSPIETDAPEQLPETLDTEKNTQKPIPQVTTTEVSEQEMESRTPTTTPPARSLPGVQGYPMLENSTLKPQEKPEEQRWSPSKSPLRPPSFQGQVKLASSVSVVNTRDSHRLSFPSLKTATTFTWCFLMKRKPLHVQQMDQRISAYSAWVVNPNNPNPLGLPTKVVMSLFDSKQTSKKIHYTQAKTTTLKSDILTYSGKLKDVLPKVLIQQRSVPSENSGKTKPDTQPVNQKESDRDTSKSEPQRVKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHSDIRPFHCTHCNFSFKTKGNLTKHMKSKAHSKKCMEMGVAVGIIEDQDAEDSGDRGRAGSADRQDSDGDDSDGPDDEDNEGEEEDEEDSQAESGLSATPSVSASPQHFSANQADLAPSSLLAQMSISPNPSPALQSQPPPTSDSQTSDTESVAMTSPVSLVRQMSISASCSSPGPNPTSFTSHPTPASESHTSDTDSVHMMSPVSPCRQMSIDYPDFDVPPSPPVSGKGAKLGQVRPVSSPSLSFPSCIPSSLHVHLTPYQYQTSYAFPCLESRMPGTSAKLL", "length": 2120, "header": "tr|A0AC58HZQ6-1|A0AC58HZQ6_DANRE Computationally mapped isoform of Zinc finger protein 40 OS=Danio rerio OX=7955 GN=hivep1 PE=4 SV=1 CANONICAL=A0A8M9PBC6-1" }, "locus": {} }, { "isoform_ac": "A0AC58HZT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6/entry#A0AC58HZT6-1", "sequence": { "sequence": "MPRTKQNNPKNLKDKIEEAQKEFKDPKGAHKDTNESTGRNSESIKGLKRKKVVAQNQLKKIPKSPVKKQSQTKKSISSNISSKEATPSSFPSSPSHGSPKPEDAEDGPEEVSASRTVKVEQEEISTSEPQALSHKGAAAEPCVAEPVQTESWCGDSCNKSTQSPSHTSAPLEVLLKAMEPDFIDFTERKNSSPIGHLGKSASNPVTYSDYAVAMPAVNFNIQSQNSFMQPFNAAKQYYSSVASTGQHITQPYMSGNRQQEKPGVQKSYSVGPSLTLMHAPVPSGSGGFPQSQPPVVQTCQSLSATVPNSIQVPVTPGYNPVQMTTVVNFGASQVSDISAKDQKPKKQGKYVCEYCKRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHAIKLGLVKDSGSGSLSQESDKGLATHSDVDESGDSDEESSAADLDADSSQSSLTALSESSLQSASMIQGSQAESEHSLVFENLKPSATQRGCEPKVTAALPKVVVHPVNVSPLRADSPRVTDSAPEQATAQRQRDFQPTNLRSNVTVLSSLKEVDCTSPPQDSVSDDEDQHCKSPLGGSHAQLQRQQATDYSQQAQVKCLLSPRSLGSTDSGYFSRSESADQAMSPPSPFVKITPPGDTDITKTPHIPPCPVVAAVMHVATIEKPRVPSGQMRPPLETKALSLEERISKLISDNEAVVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPPVRRSSSNSDIPKSPFTPTDKSKQVFLLSVPSQYPAMECLPITRSNSMPTTPGQSALFPNVTTQPHQLRICQSFDDKISSLNDDVFSSAPSTPNPAVHPRTLVRQIAVEDLSTNDGHVLIQVHSMDESHHGPSITHELRSKSFEHATERNRKPQQNKGTMYECETCRNRYRKLENFENHKKFYCSELHGPKNKPMHARETEHEVFGRGIQQPLLNRNAVITGNVEQPLMLRKRRKIKSVGDDDDQSPTETTPPCSRSFDSSQSSTGSIGRTNSHHTQSLGNSAILGQIQIIARAGELQESRLSPIREAQISTPCKERGDLQRQGSGTSVIRHTNSLSRPNSFETSESIDRSSPVDPVEKETKISVKSHTETAVSSSQSYHDRMSTPKCPSQTHEKQSFAIVGDVPPVQQSRLVRQSNIQVPEILVTEEPDRDHETQVVESTEKPAETFSWPQRSESLSKLPTEKLPPKKKRIRLAQMEHSSGESSFESSLSRSLSRDSSLSRCSSISASFDRDDPPRSDSPSRADSVGKPPETQGVPVANNTLGVPGIMRRSTSEQISYTQSSVEISCDYRSKSFDCSSMSPSRPLSPMQTALPKTTQCPPSTLVPLIERRRGPLVRQMSLKIAPEPQIAVKQTTPIQRVPFTNECSGSQPRSVNLNTSALAQCFAVHSGEVSLPKNEQVVQSINLGGKTEQPQVHGLPHPWHQTSRVVAGHVQPLVHMVGGQTDIKKSSDEKNKIFIPKYQMNCPVLKTGQTYSLAGVQGTQIPLPVITIPIANEIKGSHSNDGMQNVYVAQSSYQAVLNKPSIVQPSNAQVDTASHKVPVSAPVPQILITHEHTLASASAVSKVSFPIAPSVNRDSKIGPEIQAQKQPGSVAVQMKNNMKTTDQIQNTEQSILSLGSLHCMQKLASANLCPQESTASSKRMLSPANSLDIAMEKTQKRAKDEHGAACLTDGRSLNYLNSKMSEITRQRKLMLVRQVCTTEPVDSPIETDAPEQLPETLDTEKNTQKPIPQVTTTEVSEQEMESRTPTTTPPARSLPGVQGYPMLENSTLKPQEKPEEQRWSPSKSPLRPPSFQGQVKLASSVSVVNTRDSHRLSFPSLKTATTFTWCFLMKRKPLHVQQMDQRISAYSAWVVNPNNPNPLGLPTKVVMSLFDSKQTSKKIHYTQAKTTTLKSDILTYSGKLKDVLPKVLIQQRSVPSENSGKTKPDTQPVNQKESDRDTSKSEPQRVKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHSDIRPFHCTHCNFSFKTKGNLTKHMKSKAHSKKCMEMGVAVGIIEDQDAEDSGDRGRAGSADRQDSDGDDSDGPDDEDNEGEEEDEEDSQAESGLSATPSVSASPQHFSANQADLAPSSLLAQMSISPNPSPALQSQPPPTSDSQTSDTESVAMTSPVSLVRQMSISASCSSPGPNPTSFTSHPTPASESHTSDTDSVHMMSPVSPCRQMSIDYPDFDVPPSPPVSGKGAKLGQVRPVSSPSLSFPSCIPSSLHVHLTPYQYQTSYAFPCLESRMPGTSAKLL", "length": 2297, "header": "tr|A0AC58HZT6-1|A0AC58HZT6_DANRE Computationally mapped isoform of Zinc finger protein 40 OS=Danio rerio OX=7955 GN=hivep1 PE=4 SV=1 CANONICAL=A0A8M9PBC6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2114, "start_aa": "Thr", "end_pos": 2114, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2114", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 317, "start_aa": "Thr", "end_pos": 317, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr317", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 88, "start_aa": "Thr", "end_pos": 88, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr88", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100000517", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000517", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1M1T1-1", "protein_name": "Zinc finger protein 40", "gene_name": "HIVEP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPRTKQIHPRNLRDKIEEAQKELNGAEVSKKELLEAGIKGTSESLKGVKRKKIVAENHLKKIPKSPLRNPLQAKHRQNTEESPFPLLAGAAEPHKKQSHSPAKAGGRPLTKHNGETPGLTAGAPKPEAPVCPRKPPLLLQPSEPRRWRSEGPDLAKAGVPEGKSDPGSPPSKGKAEHREAPASSGHSSPPSSFANTAFDVLLKAMEPELSTLSQKGSPCAAKIENLRPNKTARAPTHLHGGPREAADPHLPDAAAPSEQPLPPRTLYPSGPVSATQRRDPAVVPASSPAYHIHELPVPKHGPQSQQLPACSGFPPSLASLQGQENAQLEHVYTAAATSPPGRTQVTPSNQQVDAAVSVPVSPTPSTQSPPTPIYNSSPVAAVVNHSVEQMCSLLLKDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHTIKLGLVLQPDAGGLFVSHESPKALSIHSDVEDSGDSEEDGAGDERPNDPGSVDLQPVQMIRMLSSSEALPKSGSIPSNPERMVGDFALQDGSSESQAVAELPKVVVHPISVSPLRVDSPKVTDSKPELPGTQKDLQGTRVLSHPAWASSLEADEKAHQKGDPTQPDGKPESPVGAAHAQLQRQQATDYCQEQQGKLLSPRSLGSTDSGYFSRSESADQTVSPPTPFARTLPAPEQDSAKNSGPSTPRVSTPAASAVPAGEKAPLLPGQMRPPLATKTLEERISKLISDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPMGRRTSSSSDIPKSPFTPTEKSKQVFLLSVPSLDCLPITRSNSMPTTGYSAVPASIIPAPHPLRGSQSFDDKIGAFYDDVFVPGPNPSVTQSGHPRTLVRQAAVEDSSASENHVLGAGQPWDESHPGGSPAGETAAPRSKPPAPGSHLEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTKVAVRDPEHSSVPGGAQHYRVAGATGVWEQTTQMRKRRKMKSVGDDDELQQNESGAPPKSSEGSRSQSALGPAPSLSQQNLAIPSELQPRNLQRQTTQIQLGTRGPNQPRDPKPSSVLEEPMSSAAQDRAEPKRHGAGISVIQHTNSLSRPGAFDKLDAGEGASPVPFQELRTGKPGSLSVRGISQEEGCPSRHTSQPTLSDAPRGELQDGSRKISGERHVLGQPSRLVRQHSIQVPEILVTEEPDRDLESQGHDAEKSEKFSWPQRSETLSKLPTEKLPPKKKRLRLAEMEHSSAESSFDSTLSRSLSRDSSLSHTSSFSASLDVEDVSKTEASPKIDFLHKADFLLIPAGSNTLSVPGGHREMRRAASEQIHCLQTSMEVSDFRSKSFDCGSIAPSQKVPPAESHPPTSPSGVGVAGHVPLLERRRGPLIRQISLNIAPENQLAPGNPLSFQTIAPPAVNTVPLQGPQLTHTVSAEFPASTLHSQTPVKDVRAEMASSHSPNLFPLQQLLGIHLLNQIPVPLSHPDTHMSLQVSSTQSVKPDASPGGGCVPSKSEDCFAPKYQLQCLAVPSSQPCASNPVQPLPKQGLSDAAGATPRATSLTLPAKLAEATSNSCPPPPLKVGALGGQVPKGPTSLTLSTHLQTQVSTYCFAAVTALPQILVTQDLSNQPICQANRSTVPISEEQSSVPKPQNDPRNALPNPEGELVGQPVFSEMGQNPSPSESSPTTPKMSVGRLSPQQESSASSKRMLSPANSLDIAMEKHQKRAKDENGAVCATDTRPLEAVGSRAPDGSKQKKPVLVRQVCTTEPLEAVTLEQDVFPHPEVSTEALHLTAVSPADNVSSGHCKPVAREPMKEVQEFESIPSAALLTPTVQNPAAPAEKTHISPLESIDNHQERKSPGIKNPGNKANVQEQSQPAATTPSMREAGDTQPSTSFPSLKTATSSTWCCLMRQKALHLPQKDQKTSAYTDWTVSASDPNPLGLPTKVALSLLNSKQKTGKSLYCQAITTHFKSDLLVYSSKWKSNLSKRALGNQKSTVVEFSSKDASEINSEQDKENSLIKSEPRRIKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKSKTHSKKCLDLGVSVGLIDEQDTEESDEKQRFSFERSGYDPEESDGAEDDDIENEEEDEDSQAESVLSAAPSAAASPQHLPARGGPGDPTGADEDASAPEGSPGGPTDAMDVLPRALPTKMTVLSALPSDRGGSPGSPGSAGPRAAGNAEAAACPPEGAPRSPCHQMSVDYPNPKEMLSGSAAGKAVALTQGAPCLSLPPPPASERSPQPGGAPPSTSPRPGPQEQKPQAALPPPAGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIQVVPAGLTYSTFVPIQAGPVQLTIPAVNVIHRPLGTPGDLSADGPGTASPAGVAELSSVVPCIPIGQIRVPTLQPLPALSMETVNIVGLASASLGPPVRPPGLALNAVGLQVVAANPASQSSPAPPAPIPGLQIVNIALPTLIPSVSQVPVDIQGAPEMPAPPNRASREAPPTQPVGAHPGGRTPSPQGSPGVQRESAQKGLDPPAPARDQARRDSSSPRDTGKGASANHPKPRHDTPGAPCKPTSAPLPPPGRPRLPLDPEGPRPPPRRPVTQFSDVSSDDDEDRLVIAT", "length": 2684 }, "evidence": [ { "id": "A0A8M9PBC6", "url": "https://omabrowser.org/oma/group/A0A8M9PBC6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8M2B7M4-1", "protein_name": "Transcription factor HIVEP2a isoform X1", "gene_name": "hivep2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEPHEPIVGQKCTKEQREKNPLQRKWVSEPSAGTKRNTFADPDIKRHSHREQSLTGGTNLTSSTQKYSSGNLMSSAVTHSSQEGQFQQIFPRPYPYQLPHSYPQEPFLGGTKPQPGLEAHAWSFSGQLQSLPPDDMYPVHSRSHGVFPRHKSPAGFGQFSQSGPEQPDESHKKEQKPKKPGKYICHYCGRACAKPSVLKKHIRSHTGERPYPCVPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFSDLATRTDTDQASSVGEAEAHSDGEQSTDTDEETAEGAMFPEKCSPQISFESDKSPMERGPAYADPAEELSVASMKVPILIVPKQGVPSPATECPQFTDIKGSVIGGQMGRGDESHTVKQRLALRLTEKKDLDSEQSQNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNVKTYEEIMFGRTWYHRTNSRSRQSVTVGMVAIASQDTNINKSSAMQELAMGKISEGHVFYQSDCAESHLIPGCDPKHYHAGSCQTSTGLLEAPSDSGPLIRSNSMPTPSPTNLNVPPNLRGSHSFDEMMTQDDVFYTGAAGLKRLRRQSAFEHSVQEGHGESESYGKITGPNSSLRGHLMPELKGSGSEMACPEVRTAYTSYGTKVGMTEFTTRKRRMKKSVGEEEDCLGQDDGSRSGSTEMAEEYDLRQGSQDSSKAVPANKGSMFRAHSPSDSFDRGSCMTPEDVVHVQDSDTKTGGNVISVIQHTNSLSRPNSFEKTESIEHPFYQPDKHAGHLSEQSDTENIDDVQSPDSHHRSESMEHQQQGDNEHGSFSSNTLYHMPHKLVRQPNIQVPEIRVTEEPDKPEKEPEVPAKEPEKHVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTCTSLSRSPSQESNLSHSSSFSMSFDREESIKSVSPTKQDEFAKQSEFLTVPGSGHSLSIPGHHQREMRRSSSEQAPSALPTEVPEIRSKSFDYGSLSTGSRQGEVYASASAMKERRRGYLVRQASLSVYPEVVVQEPISELSIKQEHSDHVSQAGLTGTSYCVANDLPRPRRGAQSVLGSHLLLQQSISEDSQSEDHFQNTPRLPAQLSSDSEHSVHEHMTQDLFQHSSLQSSMASSPFLPFQPMLWHPESTQRNKHNLAFQSHNLQKLHIKQPNLQPLLQKPYQPSHQIQVQTDSKTDGASHNYPYPSRASPQQLGVLSSKVLTTSFLQQVQPTFATQNVGSPQSLPGMLVPVRIQTNVPSYGSVMYTSVSQILVTHAQSTTSIRVICTDNVSTASITGTASKHQVGINLSKILGHSGGSINFPTWKVPEYLPGSLNTGIPLSLTSGTISTTDASSNIGGSKRMLSPASSLELFIETKQQKRVKEEKMYGQIVKELSAVELSNSSAPKDNESTKAEFSNRDDSIDEQERMSSSPPSDFLSSKYLGYPSAPRLPDVPPKDNFIPPLQIITNVTSRADSPEELDVDESTPEASSSPQSVMSSSDTQEESKQSMGNKFPVNMLVQLAANQGGGVVGSTLMLTDLADVHQFFQFPSLRTPTSVSWCFLNYTKPNYAHTTPLSSVYGSWCISSYNPNPLNLSTKATLALLRSKQRKNTEMYTMAAMHQPGTGKLVSSLRWKQKFEQLKPEHIQLDVGKFAKKMKGISSRDRGKEDHGEKEACSKQAEPTRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKFCNFAFKTKGNLTKHMKSKAHMKKCLELGVSVTSVDETEAEELDTTEEVQRGSEKKGMSEIMAEHQFSDADDSEGAEEDGDEVDDDEDDDDDYEGDSTPKTRSRSTSPQPCSIPSLAITAIAASQESIPEGLAISKQPIFTYFTSLPSIQITQLMAPSEKAGEIQMAEYQKLLQGALGEDHKNRLDVPSSMDEDLALSPEHSSSSFEFSCSRLSSPGCDSSPLRESSPSSRRYLSPRRDLSPRGRLSPRREASPLRHISPRRDVYRRDLSPRRDLSPRGHLSPISQTGRPTSPGRDLSGRLSPRSRRGMIRPVSPRRGLHYQSGPWALSPSPHAEMISLSQKTKGHAEPEMDQRKTSHLQGDPRNTDAPSINQGLFSHLPLHSQQQIRTPFSMIPIGGIQMVHSVPTSVTGHAHSTRLPLQKSTSEESSTSEVSFHLSEGRGPASKGSEDSPQSQEKSTSPKAPSLSPQKSREDSTEMSDKESKQEECIQTCTKAIASLCIASEETTDRQPLPIDPYHQRTLSQSPAAQQDCAARAQHYCSSEISHPLHSRAESSVSATSKTPTASHPTLYNTETAERVSGQQSRGERPATIKKSKDSKDNR", "length": 2323 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PEH8-1", "protein_name": "Transcription factor HIVEP2", "gene_name": "hivep2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEATKTSGEVESSEQIISFKDDEKHLPSEMTQRGQSSGSEDKIRLAEQPQTPSVSPSPGIEPQVLASGNTLTSKSKEQSHVQLRRKNVPLPNKRYLQAEYEMLSGGLHKKEQKSVKTGKYVCQYCGRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHTHAVKAGLVSVSEQDCKNTDEVAEGEMHSDAEQSSDTDEEVAEDLSLDTTSHIKETEGYVQEKVGKLAKKEALFPSQTPLKKETGPSGKVSLWQFREMTAPVAIAQIDQMVEFSTIKQKLALRLSEKKSQESDQSLSLPSSYSKGSTDSGYFSRSESAEQQINQSSASAKSYQEIMFGKCYRPATRPKQSITVQTCMTDINEATSSFMITLNKGMMPGDTDSSIHRSKKDLVRSIKIDSESFQEEDYQECQIPSSDLLETALESSVFLRSNSLPTSSKSNLNTPQGLRSSNSFDERMTGADVTYRGAMGMRRLMRQSAFEHSANEGHAESDCYTHLACSLKSDLKIHSIDDSKMAAENFQETETCSVCPGHSSESSTRKRRKDKTVTEEEDFHIQDKPSNVTGLSEDLETKQISSDSVVSDTERKAGSNVISVIQHTNSLNRLNSAEKLSEVRSHQLDKIGKFMEKGHSMECHRTGSECQWGPCGFLHQKLHMHKQPTSQPNIQVPEIRVTVEPDRPEKVPDVGVKQREKHTEEFQWPQRSETLSQFPMEKLPPKKKRLRLAEMECSSGESSFESACTSLSRSPSQDSNLSHSSSFSQSLDREETLNLVSQINPDESSKPLEFLSVPGSSQSHHREMRRSASEQAPYKLPSEIAEFRSKSFDYGSLSPSSTYRLEEVKERRRAFLVRQASLSGEPETQGGNFSDEISKRTTLPFTPEGSIEKMRYSLISGSSFPHHRQYSPVQSSSQHVKPTVCNVHDMENVMLVIKKEPEESKSPETYVNLREPQEDCSQSLGNVLSTIAVLSQAQQALASQCSSGLLVPVRIQMQVPSYGNITYTSISHILDSHIQKPISCLEHKKSSSQSQQLHSLQASPAKLKTGIPLSLTSKTISTTEAPSGGANKRMLSPASSIELFIEAKQQKRVKDENIYGQIVEELSAVELGNLEVEKESPKSEFTSEPIDKMDMDEATQEFYSNAELQSSARISQDAAIMEQKPTPESMMASHHSASCISLMPSAITGTLLFSKFPGLHTTTCMSWCYLNTTKPNSTHTVAPFSEYASWFVRCHNPNPPDISTGMVLALLRSKQQRQNAIYTIATIYQPGLLVTSTPWTPKQEQIALDYREEDTKQDIRLREISHRGKSLREDVSSIIRQTEPMRVKIFEGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHTDVRPYICKCCNFAFKTKGNLTKHMKSKAHMKKCLELGVSPTAMDNTEDADDTQKSLGIMPAEQTIKHQFSDVEDSDGADEDEPDEDEDDECDGDSTPKTLSRSTSPQSYAVNKPCMSGCLPKHFDSGCNLPKEQLEASSLTIEDDLNSDQSSCSFELCPPQLLSPCWDSPRQRYMSPRGDLSPQRHLLSSRDSSPLRAVSPRRDLSIRGDFSPIRQLSPVRPTGLDTSGQRAQSPLGRHKVALRAVSPRRGSYQHRTHMDLGRSVRFQASPIRPIIGETGVDQGDTSLNLIVPVGLCSSKDLPKTRQPDIFSHLPLHSQGQVSTPVPMVPIGVLRMPSISTSGAVAERNSLPSIPQGNILETAAPGQTSASVPDPAVAYSGEIATYSTGLPNKDDKKEESVYTCAKAIASLRITSEDASDNPPKS", "length": 1798 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z8F4-1", "protein_name": "Protein schnurri", "gene_name": "shn", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARRKGSGRGKSTVNSRKSALETAREKTKDEPTANTSQDNKFDNNMENATTTTAKHYKTAGKQYKTNKVNNTRRATAAAAAAAAAAATTTVTTAATPTKKRTYRETATATIVTQRSTNKANIAAAIALAAATEATASASASATATATDATLTASKAAATAAATTDAASGNSNSSSKPSTSTRDKLGEVPLPTVDSNHIISNNNNNNNNNNTSNNNNNNHHSDNSISENNYEFKSRDKASLSDSKMTLQQMAAVSSNQEPVAPNVANTMSNSSIINSQQTTVNATPATDEAPLGDRSNISRYLHKKFKRLASTTEVDSWSATNGGGALQASGDAVRTTSLSSNSSLSPPPTTPLANGHHLMTQQQSHQQVQQQQQQQQTPPPSVAIHEFSANFVNSNHVNAIGHEESIISNSGYKAAGRTRTPLANSNSNTNSTSNSNSNHAANATLSPASFAQHQQLTQPTTVSPGIPGGAAAPNPACEKSGRYVCQYCNLICAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARARGLEVPADADDGLSDQDAELSNSSSELPSRAGSPYEEPINSPTPSPSTLSAAKSAYIQQPPLPTYMQQLPLGSPAAGTLPPTTADNHHSATAQHRQSIDYKPYKPKFHNASLYSCSSKELQQQQQQLQIQQQQQQHQLAQQKLSIQLPLVQQPSLAHPTLSPSTQMKMKHHINSHQIQLQLQQQQSLLAQQSLLAAMPPGGVYYLGQPSYYNQDTAAAIHQHALAIQQFQIHLAQQQQQQQQQHPPLVKATPPMQQPPSLPPQQLVRANSQISSVATAPATPTPAANLSTFASSSGGKQVNVAKVQEHISKLISQNEAIVENKEILLQKKYPKQLSRSRSFNNANSNNASQHGSNASALHANNSQNNTNAQMPERETKVNLAQAIFQKQQHQLQQQQQQQITQQQQQQLEQQNYYTYIQQQQECQQQQLEPPNGVVKRNAYKPGVVMTTPVKQQQQLPPPPSPLPMQTMQYRQDPATPVTKIEQPTTAVPVMPLNLSAKPKPTLVTVPVSSLSTSSLAPTPTTSTNPTSSSKTAPPPAQVNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICASEFRSADDLKLHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKSHMANSKNPLSLAKLAWSQLKTKRSSLVLSRLSAAQTPARTSTVTAPTVTASAPAPAVATVTAPSSAPAPQIEALRFVDAPLPSPGPLLGKTPLVDYAQQSTPRKAQDSVVITKMHEDRQFVIEAQPAKRIKTSDLVVASSSQQPTSFNFSFNNQNSSNSVPELQSSKEERLRRFTSSGGSMIPISECPDLDNSPKMIRTPLLSGGSFQDVSVKVNNETGSSSKERKLMALVSGSGLLGVSSGPQHFQFPPINSITAFNPLTLPPMSGGDKTTPVTPIPHVPGMPGPGSLTPQMPLLPPPPQQLQLPIPSSRGRSPNRKQPSPLLLGGGSGELKALSPFGGVQNVPSEFSRQPPTPAQRQALQWNSKEAPKKAPFNFLRMADNVKTTEPEVRHFNLENVISGKQQELPLTPLHVDTPNGNAPEETSPVASASASAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKQVMALYDSRQRMLGNGSSTAMAGSGKLSYNLVASQQIVSSPSTSSTSSAFYQGPLKTPPTVTIAALSEANVAAKANEEAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPPDSEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRQKEHEAARGLLSLSMTPPIPQSVSPYPQLQDTPLPAASPANSIGSSGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVANEESAPMDLTKPRGSILLISPSPVSVPAHDLPKSQAQQMHDVIFGTSGNESGFMKTLISVSDKVRISAEMEEQAKHEAEGEDVQLQTYIKEHALHQAKIKQSQFSRSYLINTLYTAASPVMSSSSTLFTANSRPVMSVNEVPSIEVHEVKTPEAIESPRSAPEQAPVILAQIAQEENEEPNIAEPHNANLPAAVQQPDVNEFTGVLGNPTAPPTSSVTATSVSTTTAAPVAPSSTANSTQPAQRTVIVGEDGFKSSTPTSKSGDLQHVSYGRGVPPAPIAGDARPTCTMCSKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLQEKDPGKLSSYTTPSGMMQLAQDAAGPVSQDSASEDGFSAAIASAIASLDNDSAGNTPKRASSMSEDETVANGLNHSLKRRLPGSFSSTGEESDNPPESSGEKRARSGQELPVPVAVPVAASAAASN", "length": 2577 }, "evidence": [ { "id": "HGNC:4920", "url": "https://alliancegenome.org/gene/HGNC:4920#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-512", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-512#orthology", "database": "AGR" }, { "id": "MGI:96100", "url": "https://alliancegenome.org/gene/MGI:96100#orthology", "database": "AGR" }, { "id": "RGD:727847", "url": "https://alliancegenome.org/gene/RGD:727847#orthology", "database": "AGR" }, { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A2A884-1", "protein_name": "Transcription factor HIVEP3", "gene_name": "Hivep3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPDQSIKGTKKADGSPRKRLTKGEAIQTSVSSSAPYPGSGTTAPSESATQELLATQPFSGPSQEKTGQQQKPARRPSIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASILPPEELPGIPKVFVPRPSQVSLKPAEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGSSSEMYPPGLEMERIPGEEFEEPTEGESTDSEEETGAASGPSTDVLPKPKHPLLSSSLYSSGSHGSSQERCSLSQSSTGPSLEDPAPFAEASSEHPLSHKPEDTHTIKQKLALRLSERKKLIEEQTFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTSMLASTSTQPLLPLSSEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLTRRSSVESPKSSLYRDSLSSHGEKTKQEQSLLSLQHPPSSTHPVPLLRSHSMPSAACTISTHHHTFRGSYSFDDHVADPEVPSRNTPVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDPTSKPSDEPEPKESDLTKKTKKGFKTKGANYECTICGARYKKRDNYEAHKKYYCSELQITKAHSVGAHEVEKTQAEPEPWSQMMHYKLGATLELTPLRKRRKEKSLGDEEEPPAFGSPGPSETAHNRPLGSTKSPAEASKSAPSLEGPTSFQPRTPKPGAGSEPGKERRTMSKEISVIQHTSSFEKSDPPEQPSGLEEDKPPAQFSSPPPAPHGRSAHSLQPRLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESSISLSGSSRSASFDREDHGKAEAPGPFSDTRSKTLGSHMLTVPSHHPHAREMRRSASEQSPNVPHSSHMTETRSKSFDYGSLSPTGPSLAVPAAPPPPAAPPERRKCFLVRQASLNRPPEAELEAVPKGKQESSEEPAASKPSTKSSVPQISVGTTQGGPSGGKSQMQDRPPLGSSPPYTEALQVFQPLGTQLPPPASLFSLQQLLPQEQEQSSEFFPTQAMAGLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPSQLHLPQLLPHAADIPFQQPPSFLPMPCPAPSTLSGYFLPLQSQFALQLPGEIESHLPPVKTSLPPLATGPPGPSSSTEYSSDIQLPPVTPQATSPAPTSAPPLALPACPDAMVSLVVPVRIQTHMPSYGSAMYTTLSQILVTQSPGSPASTALTKYEEPSSKSMTVCEADVYEAEPGPSSISKEQNRGYQTPYLRVPERKGTSLSSEGILSLEGCSSTASGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVSTCSVVLTSTEDRKKTEKPHVGGQGRSRREAETLSSLSSDVSDPKELSPLSHSTLSHGTAPGSEALKEYAQPSSKAHRRGLPPMSVKKEDPKEQTDLPPLAPPSSLPLSDTSPKPAKLQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSNSRKPRMTEVHLPSLVSPESQKDPARVEKEEKQGKAEEGTPTSKRGEPARVKIFEGGYKSNEEYIYVRGRGRGRYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLHQDSEGQEGAEAVEEHQFSDLEDSDSDSDLDEDEEEEEEEEESQDELSGPCSEAAPPCLPPTLQENSSPVEGPQAPDSTSDEVPQGSSISEATHLTASSCSTPSRGTQGLPRLGLAPLEKDMSSAPSPKATSPRRPWSPSKEAGSRPSLTRKHSLTKNDSSPQQCSPAREAQASVTSTPGPQMGPGRDLGPHLCGSPRLELSCLTPYPIGREAPAGLERATDTGTPRYSPTRRWSLGQAESPPQTVLPGKWALAGPCSPSADKSGLGLGPVPRALLQPVPLPHTLLSRSPETCTSAWRKTESRSPSAGPAPLFPRPFSAPHDFHGHLPSRSEENLFSHLPLHSQLLSRAPCPLIPIGGIQMVQARPGAQPTVLPGPCAAWVSGFSGGGSDLTGAREAQERSRWSPTESPSASVSPVAKVSKFTLSSELEEERTGRGPGRPPDWEPHRAEAPPGPMGTHSPCSPQLPQGHQVAPSWRGLLGSPHTLANLKASSFPPLDRSSSMDCLAETSTYSPPRSRNLSGEPRTRQGSPELLGRGELRTPLFLPKGSGPPSI", "length": 2348 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZRB5-1", "protein_name": "Transcription factor HIVEP3", "gene_name": "Hivep3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPDQSIKGTKKADGSPRKRLTKGEAIQTSVSSSTPYPGSSTTASSEGASQELLAPQPFSGPSVALREGAQEKTGQQQKPPRRPSIEASAHIPKLPQHPLTPAFMSPSKPEHLLEGSTWQLVDPTRPGPSGSFVAPGLHPQSQLLPSHASILPPEDLPGIPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGSSSEMYPPGLEMERIPGEEFEEPTEGESTDSEEETGATSGPSTDVLPKSKHPLLSSSLYSSGSHGSSQERCSQSSTAPSLEDPTPFAEASSEHPLSHKLEDTHTIKQKLALRLSERKKLIEEQTFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTSMLASTSTQPLLPLSAEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLTRRSSVESPKSSLYRESLSSHGEKTKQEQSLLSLQHPPSSTHPVPLLRSHSMPSAACTISTHHHTFRGSYSFDDHIADPEVPSRSTPVFTSHPRMLKRQPAIELPLGAEYSSEEPGPSSKDPITKPSDEPEPKESDLTKKTKKGLKTKGVNYECTICGARYKKRDNYEAHKKYYCSELQITKAHPAGAHEVEKTQAEPEPWSQMMHYKLGATLELTPLRKRRKEKSLGDEEEPPGFSSPGPSDAAHNLPLESTKSPAEASKSVPTLEGPTSFQPRTPKPGSGSEPGKERRTMSKEISVIQHTSSFEKSDPPEQPGSLEEDKPLAPFSSPPPAPHGRSAHSLQPRLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESSISLSGSSRSASFDREDHGKAETPGPLSDTRSKTLGTHMLTVPSHHPHAREMRRSASEQSPNVPHSSHMTETRSKSFDYGSLSPTGPSVAVPAAPPPPAAPPERRKCFLVRQASLSRPPEAELEATPKGKQESSEEPSASKPSTKSSMAQISVATIQGGLSGSKSQMQDRPPLGSSPPYTEALQVFQPLGTQLPPPVSLFSLQQLLPQEQEQSSEFFPTQAMAGLLSSPYSVPPLPPSLFQAPPLPLQPTVLHPSQLHLPQLLPHAADIPFQQPPSFLPMPCPAPSTLSGYFLPLQSQFALQLPGEIESHLPSIKTSLPPLATGPPGPSSSTEYSSDIQLPPVTPQATSPAPTSASPLALPACPDAMVSLVVPVRIQTHMPSYGSAMYTTLSQILVTQSPGSSTSMALTKYEEPSSKSMTVCGADVYEAEPGPSSISKEQSRGFQTPYLRVPERKGTALSSEGILSLEGCSSTASGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVSTCNVVLTSTEDRKKTEKPHVGSQGRSRRETETLSCLSSDVSDPKELSPLSQSTLSHGTAPGSEALKEYAQPSSKAHRRCLPPLSVKKEDPKEQTDLPPLAPPSSLPLSDTSPRPAKLQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSNSRKPRMTEVHLPSMVSLESQKDPARVEKEEKAEEGTPTSKRGEPTRVKIFEGGYKSNEEYIYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCRHCHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLLQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEEEEEEEEEESQDELSRPSSEAAPLCLPATLQEDSSLIRGPQPPDATSDAAPRGSSISEATRLTASSCSTPSQGTQGLPRLGLAPLEKGTSSALSPKATSPRRPWSPSKEAGSRPSLTRKHSLTKTDSSPQRCSPARAQASVASTPGPQTGPGRDLSPHLCGSPRPELSCLTPYPIGREVPAGLESATVTGTPRCSPTRRRSLGRAESSPPHTVLPGTWALGGPCSPSVDKYGLGLGPVPRALLQPVPLPHTLLSRSPETCASAWTESRSPSAGPAPLSSRPSSAPHDFHGHLPSRSEENLFSHLPLHSQHLNRTPCPLIPIGGIQMVQARPGAHPTLLSGPCAAWVSGFSGGGSDLTGAREAQERSRWSPTESPSASVSPVAKVSKFTLSSELEEERTSRGPGRPPAWEPHRAEAPAETMGTHSPCPPQLPQGHPLAPSWRGLLESPHALANLKASSFPPLDRSSSMDCLAETSTCFPPRSRNLSGEPRTRPDSPELLGSGELRTPLFLSKDSGPPSI", "length": 2349 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9H4-1", "protein_name": "Zinc finger protein 40", "gene_name": "Hivep1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRTKQIHPRNLRDKIEEAQKELNGAEVSKKEILEAGVKGASESLKGVKRKKIVAENHLKKIPKSPLRNPLQTKHKQNTEEPLFSALQSAPESHKKHNCVPVKQGRQFTKQNGETPGMTVEASESGDSVSPKKASSPHHRSELRRWRSEGSDPARLSGLDGQRDSSSSSSKTRTDNSECSSPCCSTTPPSYTSTAFDVLLKAMEPELSTLSQKGSSCAVKTEKPRPNRTVRSPSKLKNSSLDAPNPASPELVAESQCSPCTSYPVPVASTQKSEQVAAQRVSHLHSQYDHLVPKPGQQNPQLPGHLGLAGSLTNPHTHENTKLEPIYNIAMTSTVGLASPSSRTQVTPPHQQMDSVSPSSVSPATSTQSPPGPIYSSTHVASVVSQSVEQMCNLLLRDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHTIKLGLVLQPEAGGLFLSQECPKALSVHSDIEDSGESDEEGPGDGRQNDPSVRDLQPVQIMKMPSDPEALPKSIASRADHVVSGFSSQDRPSESQALTELPKVVVHPVSMSPLKTDSVQVASPKPELPSTQSQKDLHAASRLSHSAGVSSLETDETCHQKGDVTLSEGKPEPHSGAAHAQLQRQQATDDPQEQQGKLLLSPRSLGSTDSGYFSRSESADQAMSPPTPFARTFPTTDPDPAKNSGPAGPRISAPAPAALAPGEKSSVVAGQMRPPLATKTLEERISKLISDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPMGRRTSSSSDIPKSPFTPTEKSKQVFLLSVPSLDCLPITRSNSMPTTGYSAVPANIIPPPPPLRGSQSFDDKIGTFYDDVFVSGPNPSMPPSGHHRPLVRQAAVEDSTASENHVLGSGQSVDESCQGCPASSEPGPVQSKAANTPHLEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTKVAAREPEHGLAPGGVQPQVLHYRVAAPTAVWEQTPQIRKRRKMKSVGDDEDLQPRESGRSPESAEALQLQPVPGSAPSPSKQAPATAGDQAHRGVQLQSSPVQLVARVPEQALPLKQCPVVEQQLNSATQDRIEVQRQAGGISVIQHTNSLSRPSSFDKLEPLEGGTAFSLQELGRAGMPGALKVIGMPPEEGHPPRDATHQIALSRESARKIPSERFVLGQPLRLVRQHNIQVPEILVTEEPDRDLEAQSHDEEKSEKFTWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFESTLSRSLSRESSLSHASSFSASLDVEDISKVELSPKTDFPSKAEFLFIPLGSNTLSVPGSHREMRRAASEQISCVPTLMEVSDFRSKSFDCGSIAPSHVVPALVEPQPSNSPSGVGGTGHVPLLERRRGPLTRQISLNIASDSPLSPGSVSALQTIVLPGVNAIPLQALRPPDVASADLPAHTVPSQALAKDLQAEMSSCSSTDTFPPQQLFGAHLLNKTNMPLSHQNTPLPLPVSVQGGKPGAPPPAGTSSTGDGSFAPKYQLQCQAFTSGRGCSSSPLHSLPNPVLPDQTAADPCTASVALSAKAVDPVSKSYPLPSLELGLPSDQVQKRLPSFVLPVLQPRDVPVYCLSTVTSLPQILVTHDLSNTPICQTNQSIVPVSEEQNPMPKSQNYLQNALPTPEKDLACKTVLSEMGQNAPVSESSATVQKVSAGRLSPQQESSASSKRMLSPANSLDIAMEKHQKRAKDENGAVCSTNIRPLELPSSRANEGHKQKKPVLVRQLCTVEPLEGTALEQDPGSASGKSSRNADSTQVLSTDSLSSRHSMFAVPDHVSEFQEFKNTKLSTSLTPTVGSSHIPLESACVLPLKSRDDNQEKGSSGVQNEENKVIQGQRQPPIPGLSVLSSSDTQQPSFPSLKTATSFTWCYLLRQKSLPLAQSDQKTSAYAGWTVSPSNPNPLGLPTKVALSLLNSKQKTGKSLYCQAITTHSKSDLVVYSSKWKNNLSKRALGNQKATIVEFSNKDDSEINSEQDKENSLIKSEPRRIKIFDGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKSKAHSKKCVDLGISVGLIDEQDTEESDEKQRFGCERSGFDLEESDGPDEDDNDNEEDDDDSQAESGLSAAPSVTASPQHLPSRSGLQDPGSVEEDLRVSSCFSGVHTDPMDILPRALLTKMTVLSTVQIDPNRTDLTAKARQNTGKDELELAPPVDTPISPEVTPRSPGHQMSVHYSESDALRSPAAGNTVASIQDSPSVGLPPATIAQLNPQPAARISSSVSPHPESQEPKQQITLQPSPGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVPAGLTYSTFVPIQAGPMQLTIPAVSVIHRTVGTPVDTITEVSGATNRPTGVAELSSVVPCIPIGQIHVPGLQNLSPPALQSLSSLGMETVNIVGLANATVGPQVHPPGLALNAVGLQVLANAPAQSSPATQTHIPGLQILNIALPTLIPSVGPVAVGTAGTPETATSNSKTVEPQTPAGQGHSAEPPQRLPEGPQETPQTVPGPSVDHARPDGSSKMDTKKVASASHVLPGRSSAQAQPAPIPEALQKIVASGPTSLPTDRPAPRPPVPHRQPIVHFSDVSSDDDEDRLVIAT", "length": 2691 }, "evidence": [ { "id": "HGNC:4920", "url": "https://alliancegenome.org/gene/HGNC:4920#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-512", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-512#orthology", "database": "AGR" }, { "id": "MGI:96100", "url": "https://alliancegenome.org/gene/MGI:96100#orthology", "database": "AGR" }, { "id": "RGD:727847", "url": "https://alliancegenome.org/gene/RGD:727847#orthology", "database": "AGR" }, { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" }, { "id": "A0A8M9PBC6", "url": "https://omabrowser.org/oma/group/A0A8M9PBC6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q7V2-1", "protein_name": "Transcription factor HIVEP3 isoform X1", "gene_name": "hivep3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEALHSQATTGEQSGGLAKQNETPVDNPKPQYHEEKKVVTQVHHAQQRKHLNIERKRLRLQRKSLQERDVVEEGKPPRASGSSEHLNANMSQAREMPSGASSSAVSAKPSCSMEEVLEGTPRQKRERKPQKPGKYVCSYCGRACAKPSVLQKHIRSHTGERPYPCAPCGFSFKTKSNLYKHRKSHTHRVKAGLTADREGPGISCSEEPLTDSDEESQPSSYLEKQRMSVQNSSATERCSEGQLQEIEDSHAVKKRLAMRLSRGRRTPLGSSDEASSSFGQSSKGSTESGYFSRSESTEVSQDSPPNTSAKSYAEVILGKFGRLGHLQRTSHQQHAHPAGQEGKRIPFNVPKKQVIDHITKLITINEAVVDTSKIDSVKPRRFSLSRRSSTELKVVSSKEPFLHSPKEIDISAKSSGSITLGVPCEKFQHHSLSIPQTESTSTAPLLRSHSMPSDASTSDVSETSRSLRLSQSFDDPQPIQNRRHGMLRRQPAIELPIGAELTMEEQSYSTSSFHHPVTTMPDPSQKQEQFECGACRIVCNDVERYQKHKQHCCTVHISQQSEIPVYQVDESTRTFTSRSGAFAFRKRRKEESIEFEDPSLPSVSYIPLRGYAPSCEQPIKRTHELGQEYCTEGSLKGISVIQHTSSFEKHDNSKTDEPSHTHGVSHTSPHPQTKQQATKLSFRKLVRQQNVQVPEILVTEDSNTEAMAVSPPPIVPKMKDTEKVSEFQWPQRSPTLAQLPIEKLPPKKKRLRLAEAAQSSGDSSFESMSLPHSPSQDSCTSHNSSRSTSFEEAGKADADLTPTRRSRATHTLTVPINSHREMRRSASEQAPHIPQTANLITEIRSKSFDYSSLSPDRTPAGWKERRKCLLLRHSAVREPEEEDQTTKVFNTSSPTCRTSTSPSHSPVTSYSPSTHHVSSSNTVHSFGEKQIMKSQDVLSENTQLSTLQLTPVIHTDHPTTVGSLICPSGAARAHYSSMSTGLKLEIPMEKDQPYITHCHQHQNIGFDVTSNPEVLRPLPAQSIPVRLNSHLPYHAGSIYTTVSQTFFSRPQEPCCSGVSSVAVVSKYEIMDQQPDSERSDSVSVGATKRVLSPTSSNELNPESEQQQKRVKEEEENQENERRDDKVLIEFKKEEILGEQSVIFPTEHKDPPFQTLNTNLTFSWCFLNYIKPNPSIQSEQQNSVYSSWCTSTRNPNPPGLTSKEMLSLLQCRQRHETLLYTMASMSPSLDVKQETPDSQKPNVTEVHAAQLTEPKEAQQAELTEVETKTTEEKEDQLSTSKCSSRVQICEGGYRSSEEYVYVRGRGRGRYVCEECGIRCKKPSMLRKHIRLHTDARPYVCQHCNFAFKTKGNLTKHMKSKAHGKRCPEGPAPGPVQCELETDEGGDSAKHFLETEEVEEHQFSDAEESDDEAEDNDEGDEQTSCSSSSSKWTSISRDDSGSCDILGLSNPGWEQHPKPPVSMSPRKPSHYGEASSPKTTKSIVTLLHLDPTTGMCSSPIRSLSPGLQMSPALPQSPGRDMSPLRCPSPRLSLSPSSCLSSLSPSDRSTSSFSERRVSPIRDLSPIRPSSPSCPLALTVGASVTIQYQADRPRASTKASPNRLNLKKKTEKTHSPHRRTNMTQSWPPAHGRLSRNMQPREGQRVLSHLPLHSQPQVMIPNLSLTIPIGGIQMVQPRSNMLLRSTSLNHSVAQMTVTVLTKEKGAGRSPVGEVPHRKNQLIVFTEPAVEMSSKSEASSDEDKEQIHGVVQAELFSRKKEVPSVAMTTWKSISQKNNRKHSRSPKKTQPVDGSRTSMDAKC", "length": 1797 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P15822-1", "protein_name": "Zinc finger protein 40", "gene_name": "HIVEP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRTKQIHPRNLRDKIEEAQKELNGAEVSKKEILQAGVKGTSESLKGVKRKKIVAENHLKKIPKSPLRNPLQAKHKQNTEESSFAVLHSASESHKKQNYIPVKNGKQFTKQNGETPGIIAEASKSEESVSPKKPLFLQQPSELRRWRSEGADPAKFSDLDEQCDSSSLSSKTRTDNSECISSHCGTTSPSYTNTAFDVLLKAMEPELSTLSQKGSPCAIKTEKLRPNKTARSPPKLKNSSMDAPNQTSQELVAESQSSCTSYTVHMSAAQKNEQGAMQSASHLYHQHEHFVPKSNQHNQQLPGCSGFTGSLTNLQNQENAKLEQVYNIAVTSSVGLTSPSSRSQVTPQNQQMDSASPLSISPANSTQSPPMPIYNSTHVASVVNQSVEQMCNLLLKDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHTIKLGLVLQPDAGGLFLSHESPKALSIHSDVEDSGESEEEGATDERQHDLGAMELQPVHIIKRMSNAETLLKSSFTPSSPENVIGDFLLQDRSAESQAVTELPKVVVHHVTVSPLRTDSPKAMDPKPELSSAQKQKDLQVTNVQPLSANMSQGGVSRLETNENSHQKGDMNPLEGKQDSHVGTVHAQLQRQQATDYSQEQQGKLLSPRSLGSTDSGYFSRSESADQTVSPPTPFARRLPSTEQDSGRSNGPSAALVTTSTPSALPTGEKALLLPGQMRPPLATKTLEERISKLISDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPVGRRTSSSSDIPKSPFTPTEKSKQVFLLSVPSLDCLPITRSNSMPTTGYSAVPANIIPPPHPLRGSQSFDDKIGAFYDDVFVSGPNAPVPQSGHPRTLVRQAAIEDSSANESHVLGTGQSLDESHQGCHAAGEAMSVRSKALAQGPHIEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTKVAMREPEHSPVPGGLQPQILHYRVAGSSGIWEQTPQIRKRRKMKSVGDDEELQQNESGTSPKSSEGLQFQNALGCNPSLPKHNVTIRSDQQHKNIQLQNSHIHLVARGPEQTMDPKLSTIMEQQISSAAQDKIELQRHGTGISVIQHTNSLSRPNSFDKPEPFERASPVSFQELNRTGKSGSLKVIGISQEESHPSRDGSHPHQLALSDALRGELQESSRKSPSERHVLGQPSRLVRQHNIQVPEILVTEEPDRDLEAQCHDQEKSEKFSWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFDSTLSRSLSRESSLSHTSSFSASLDIEDVSKTEASPKIDFLNKAEFLMIPAGLNTLNVPGCHREMRRTASEQINCTQTSMEVSDLRSKSFDCGSITPPQTTPLTELQPPSSPSRVGVTGHVPLLERRRGPLVRQISLNIAPDSHLSPVHPTSFQNTALPSVNAVPYQGPQLTSTSLAEFSANTLHSQTQVKDLQAETSNSSSTNVFPVQQLCDINLLNQIHAPPSHQSTQLSLQVSTQGSKPDKNSVLSGSSKSEDCFAPKYQLHCQVFTSGPSCSSNPVHSLPNQVISDPVGTDHCVTSATLPTKLIDSMSNSHPLLPPELRPLGSQVQKVPSSFMLPIRLQSSVPAYCFATLTSLPQILVTQDLPNQPICQTNHSVVPISEEQNSVPTLQKGHQNALPNPEKEFLCENVFSEMSQNSSLSESLPITQKISVGRLSPQQESSASSKRMLSPANSLDIAMEKHQKRAKDENGAVCATDVRPLEALSSRVNEASKQKKPILVRQVCTTEPLDGVMLEKDVFSQPEISNEAVNLTNVLPADNSSTGCSKFVVIEPISELQEFENIKSSTSLTLTVRSSPAPSENTHISPLKCTDNNQERKSPGVKNQGDKVNIQEQSQQPVTSLSLFNIKDTQQLAFPSLKTTTNFTWCYLLRQKSLHLPQKDQKTSAYTDWTVSASNPNPLGLPTKVALALLNSKQNTGKSLYCQAITTHSKSDLLVYSSKWKSSLSKRALGNQKSTVVEFSNKDASEINSEQDKENSLIKSEPRRIKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKSKAHSKKCVDLGVSVGLIDEQDTEESDEKQRFSYERSGYDLEESDGPDEDDNENEDDDEDSQAESVLSATPSVTASPQHLPSRSSLQDPVSTDEDVRITDCFSGVHTDPMDVLPRALLTRMTVLSTAQSDYNRKTLSPGKARQRAARDENDTIPSVDTSRSPCHQMSVDYPESEEILRSSMAGKAVAITQSPSSVRLPPAAAEHSPQTAAGMPSVASPHPDPQEQKQQITLQPTPGLPSPHTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVPAGLTYSTFVPLQAGPVQLTIPAVSVVHRTLGTHRNTVTEVSGTTNPAGVAELSSVVPCIPIGQIRVPGLQNLSTPGLQSLPSLSMETVNIVGLANTNMAPQVHPPGLALNAVGLQVLTANPSSQSSPAPQAHIPGLQILNIALPTLIPSVSQVAVDAQGAPEMPASQSKACETQPKQTSVASANQVSRTESPQGLPTVQRENAKKVLNPPAPAGDHARLDGLSKMDTEKAASANHVKPKPELTSIQGQPASTSQPLLKAHSEVFTKPSGQQTLSPDRQVPRPTALPRRQPTVHFSDVSSDDDEDRLVIAT", "length": 2718 }, "evidence": [ { "id": "HGNC:4920", "url": "https://alliancegenome.org/gene/HGNC:4920#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-512", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-512#orthology", "database": "AGR" }, { "id": "MGI:96100", "url": "https://alliancegenome.org/gene/MGI:96100#orthology", "database": "AGR" }, { "id": "RGD:727847", "url": "https://alliancegenome.org/gene/RGD:727847#orthology", "database": "AGR" }, { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" }, { "id": "A0A8M9PBC6", "url": "https://omabrowser.org/oma/group/A0A8M9PBC6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P31629-1", "protein_name": "Transcription factor HIVEP2", "gene_name": "HIVEP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTGDTALGQKATSRSGETDKASGRWRQEQSAVIKMSTFGSHEGQRQPQIEPEQIGNTASAQLFGSGKLASPSEVVQQVAEKQYPPHRPSPYSCQHSLSFPQHSLPQGVMHSTKPHQSLEGPPWLFPGPLPSVASEDLFPFPIHGHSGGYPRKKISSLNPAYSQYSQKSIEQAEEAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESAVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKMSPGPPIPLDIASRGGYHGSLEESLGGPMKVPILIIPKSGIPLPNESSQYIGPDMLPNPSLNTKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNALSVTTTSQERAAMGRKGIMEPLPHVNTRLDVKMFEDPVSQLIPSKGDVDPSQTSMLKSTKFNSESRQPQIIPSSIRNEGKLYPANFQGSNPVLLEAPVDSSPLIRSNSVPTSSATNLTIPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHVEVEHHGRMLKGISSSSLKEKKLSPGDRVGYDYDVCRKPYKKWEDSETPKQNYRDISCLSSLKHGGEYFMDPVVPLQGVPSMFGTTCENRKRRKEKSVGDEEDTPMICSSIVSTPVGIMASDYDPKLQMQEGVRSGFAMAGHENLSHGHTERFDPCRPQLQPGSPSLVSEESPSAIDSDKMSDLGGRKPPGNVISVIQHTNSLSRPNSFERSESAELVACTQDKAPSPSETCDSEISEAPVSPEWAPPGDGAESGGKPSPSQQVQQQSYHTQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAQSKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFEREETSKLSALPKQDEFGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPAEVPEVRSKSFDYGNLSHAPVSGAAASTVSPSRERKKCFLVRQASFSGSPEISQGEVGMDQSVKQEQLEHLHAGLRSGWHHGPPAVLPPLQQEDPGKQVAGPCPPLSSGPLHLAQPQIMHMDSQESLRNPLIQPTSYMTSKHLPEQPHLFPHQETIPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQAHFPHPFAQHPQKSYGKPSFQTEIHSSYPLEHVAEHTGKKPAEYAHTKEQTYPCYSGASGLHPKNLLPKFPSDQSSKSTETPSEQVLQEDFASANAGSLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGFNIAQVLGQHAGLEKYPIWKAPQTLPLGLESSIPLCLPSTSDSVATLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKDLSRPQKPQLVRQGCASEPKDGLQSGSSSFSSLSPSSSQDYPSVSPSSREPFLPSKEMLSGSRAPLPGQKSSGPSESKESSDELDIDETASDMSMSPQSSSLPAGDGQLEEEGKGHKRPVGMLVRMASAPSGNVADSTLLLTDMADFQQILQFPSLRTTTTVSWCFLNYTKPNYVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITAEIYTLAAMHRPGTGKLTSSSAWKQFTQMKPDASFLFGSKLERKLVGNILKERGKGDIHGDKDIGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDDTETEEAENLEDLHKAAEKHSMSSISTDHQFSDAEESDGEDGDDNDDDDEDEDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVPHGVPSDSSLGHSSLISYLVTLPSIRVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSCMDEECMLPSEPSSSPRDFSPSSHHSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQRDVSPRRHLSPRRPVSPGKDITARRDLSPRRERRYMTTIRAPSPRRALYHNPPLSMGQYLQAEPIVLGPPNLRRGLPQVPYFSLYGDQEGAYEHPGSSLFPEGPNDYVFSHLPLHSQQQVRAPIPMVPVGGIQMVHSMPPALSSLHPSPTLPLPMEGFEEKKGASGESFSKDPYVLSKQHEKRGPHALQSSGPPSTPSSPRLLMKQSTSEDSLNATEREQEENIQTCTKAIASLRIATEEAALLGPDQPARVQEPHQNPLGSAHVSIRHFSRPEPGQPCTSATHPDLHDGEKDNFGTSQTPLAHSTFYSKSCVDDKQLDFHSSKELSSSTEESKDPSSEKSQLH", "length": 2446 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q00900-1", "protein_name": "Human immunodeficiency virus type I enhancer-binding protein 2 homolog", "gene_name": "Hivep2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTGDTALGQKATSRSGETDSVSGRWRQEQSAGLKMSTFSSQEGQRQPQIDPDQIGNVASAQLFGSGKLASPGEGVHQVTEKQYPPHRPSPYPCQHSLSFPQHSLPQGMMHSNKPHQSLEGPPWLFSGPLPSVASEDLFPFPMHGHSSGYPRKKISSLNPAYSQYSQKSIEQAEDAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESSVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKVSPGPPIPLDIASRGGYPGSLEESLGGPMKVPILIIPKSGIPLPNEGSQYLGPDMLPNPSLNAKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNTLSVTPTGQERTAMGRRGLVEPLPHVNTRLEVKMFEDPITQLIPSKGEMDPSQVNMLKTTKFNSECRQPQAMAASVRNEGKPYPGSFPGSNPILLEAPVDSSPLIRSNSMPTSSATNLSIPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHMEFEHPARVPKILAGSSLKEKKLVPGDRSGYDYDACRKPYKKWEDPETPKQSYRDISCLSTFKHGGEYFMDPSVPLPGVPTMFGTTCENRKRRKEKSVGDEEDTPMICGGMGSAPGSMMSSEYDSKLQDGGRSGFTMTGHESLPHGYSDRLDLARPQLPSRSPSLGSEDLPSAGDPDKMTDLGKKPPGNVISVIQHTNSLSRPNSFERSESTEMAVSTQDKTPSPSEMGDSEVLEGPVSPEWAPPGDGAESGSRPTPSQQVPQHSYHGQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAPTKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFDRDETVKLTAPPKQDESGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPTEVPEIRSKSFDYGNLSHAPVAGASPSTLSPSRERKKCFLVRQASFSGSPEIAQGEAGMDPSVKQEQLEQLHAGLRAAWTTVLPPLPGDDPGKQVVGPCGQLSSGPPLHLAQQQIMHMDSQESLRNPLIQPTSYMTGKHLPEQPHLFPHQDAVPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQAHFPHPFTPHPQNSYSKPPFQADIHSSYSLEHVAEHTGKKSADYPHAKEQTYPCYSGASGLHSKNLPPKFPSDPGSKSTEAPPTEQLLREDFASENAGPLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGFNIAQVLGQRTGLEKYPLWKVPQTLPLGLESSIPLCLPSTSDSAASLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKGLSRPQKPQLVRQGCASEPKDGSSQSRSSSFSSLSPSSSQDHPAASGPFPPNREILSGSRAPPRRKFSGPSESRESSDELDIDETSSDMSMSPQSSSLPTGGSQQEDEGKARKLPVSMLVHMASGPGGNVANSTLLFTDVADFQQILQFPSLRTTTTVSWCFLNYTKPNFVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITAEIYTLAAMHRPGTGKLTSSSAWKQFAQMKPDAPFLFGNKLERKLGGNVLKERGKGEIHGDKDLGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDETETEEAENMEDLHKTSEKHSMSGISTDHQFSDAEESDGEDGDDNDEDDEDDDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVAHGVPSDSSLGHSSLISYLVTLPSIQVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSSMDEEAMLSSEPSSSPRDFSPSSYRSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQGDASPRRHLSPRRPLSPGKDITTRRDLSPRRERRYMTTIRAPSPRRALYHNPPLPMGQYLQTEPIVLGPPNLRRGLPQVPYFSLYGDQEGAYEHHGSSLFPEGPTDYVFSHLPLHSQQQVRAPIPMVPVGGIQMVHSLPPAISGLHPPPTLPLPTEGSEEKKGAPGEALTQDPYTLSRRHEKQAPHVLQSSGLPSSPSSPRLLMKQSTSEDSLNSTEREQEENIQTCTKAIASLRIATEEAALLGADQPTWVQESPQKPLESAHISIRHFSGPEPGQLCTSAAHPDLHDGEKDTFGTSQTAVAHPTFYSKGSVDEKQVDFQSSKELSLSTEEGNEPSSEKNRLH", "length": 2437 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q03172-1", "protein_name": "Zinc finger protein 40", "gene_name": "Hivep1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRTKQIHPRNLRDKIEEAQKELNGAEVSKKEVLEAGVKGTSESLKGVKRKKIVAENHLKKIPKSPLRNPLQTKHKQNTEEPPFSVLPSASESHKKHNCVPAKQGRQFTKQNGETPGMTAESSESGDLVSPKKTSSPHQRSELRRWRSEGSDPTRLSGLDGQRDSSSSSSKARTDNSECSSPCCSTTPPSYTSTAFDVLLKAMEPELSTLSQKGSSCAIKTEKLRPNKTVRSPSKLKNSSLDAPNATSPDLVVESPCPPCTSYPVHVASTQKSEQVAAQCVSHLYSSQDHLVPKLSQQNQQLPGHLGFTGSLTNLHTLESTKLEPIYNTAVTSTVGLTSPSTRTQVTPPHQQMDSVSPLSVSPASSTQSPPGPIYSSAHVASVVSQSVEQMCSLLLRDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHTIKLGLVLQPEAGGLFLSQECPKALSVHSDIEDSGESDEEGLADGRQNNPCVKDLQPVQTMKTVSNPESLPKLIPSNSDHVVRGFSSQDRPSDSQAPTELPKVVVHPVSMPPLKTDCLQVANPNPELPSPQSPRDLHVASILSHSASVSSLEMDESCHQKGDVIQSEGKPDSHSGTAHAQLQRQQATEDPQEQQGKLLLSPRSLGSTDSGYFSRSESADQAVSPPTPFARTFPTMDPDPAKNGGAPGPRISAPAPSALATGEKSSVVTGQMRPPLATKTLEERISKLISDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPMGRRTSSSSDIPKSPFTPTEKSKQVFLLSVPSLDCLPITRSNSMPTTGYSAIPANIIPPPPSLRGSQSFDDKIGTLYDDVFVSGPNPSMPPSGHHRPLVRQAAVEDSTASESHVPGSGQSVDESCQGCPSSSEAGPVQSKAAQTPHLEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTKAAVREAEHGPAPGGAQPQVLHYRVAAPTAVWEQTPQIRKRRKMKSVGDEEDLQPHESGRSPESADALQLQPVPGAAPSPSKHTSATAADQAHRGVQLVARGPERALPLKQCPMVEQQLNAAAQDKMEVKRQGGGISVIQHTNSLSRPNSFDKPEPLEGGITFSLQELGRTGMPGALKVIGMAPEEGHPPQDAMHQTALSHNLRGEPRESARKIPSERYVLGQPLRLVRQHNIQVPEILVTEEPDRDLEAQSHDEEKSEKFTWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFESTLSRSLSRESSLSHASSFSASLDLEDISKVELAPKIDFPSKAEFLLIPLGSNTLSVPGSHREMRRAASEQISCVPTLMEVSDFRSKSFDCGSIAPSHVVPALVESQPSYSPSAVGGTAHVPLLERRRGPLIRQISLNIASDSHLSPGSAAALQTIVLPSVNTVPFQAPRLPDMASADCPAHTVHPQALAKDLQAEISSSSSTDTFPPQQLFGAHLLNKTNTSLSHQNTPLPLPVSAQGGKPDAAPTACVSSTGEGSFAPKYQLQCQAFTSDQGCSAPLRSSPNQVLPGQAGADPCPASEAPPAKAADPMAKPCPLPPLELGLPRDEVLQKQLPSFVLPVPQKRNVTVDCFTPVTSLPQILVTQDLPNMPICQTNQSLVPVSEEQNSMPKSQNYLQNASPTPEKELACKTVLPEVGQSVPVSESSPTVQKVSVGRLSPQQESSASSKRMLSPANSLDIAMEKHQKRAKDENGAVCSTNIRALELPSSRANESHKQKKPVLVRQLCTTEPLEGAALEQGACSASGRSSNKAANLTQVLPTDSLSSRPSTFAVTDHVNELQEFKNTKVSTSLTPTVGSFPAPSESACVLPLKSIDNNQEKGSPGVRHEENKVIQGQRPPLVSGLSLVSSSDTQQPSFPSLKTATSFTWCYLLRQKALPLAQNDQKTSAYTGWTVSSSNPNPLGLPTKVALSLLNSKQKTGKSLYCQAITTHSKSDLVVYSSKWKNNLSKRALGNQKATVVEFSNKDDSEINSEQDKENSLIKSEPRRIKIFDGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCSYCNFSFKTKGNLTKHMKSKAHSKKCVDLGVSVGLIDEQDTEESDEKQRFGCERSGYDLEESDGPDEDDNDNEEDDDDSQAESGLSAAPSVTASPQHLPSRSGLQDPGSVEEELRVSSCFSGVHTDPMDILPRALLTKMTVLSTVQSSPNRTDLPAKARQSTEKDEHEQAPPADTPRSPGHQLSVHSSESDVLRSPAAGNPAAGSPGAAVQDSSVGLPPAVAQLNPQPAARISSSVSPHPDSQDQKQQIILQPPPGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVTAGLTYSTFVPIQAGPMQLTIPAVSVIHRTVGTSGDTITEASGSPNRPTGVAELSSVVPCIPIGQIHVPGLQNLSPPALQSLTSLGMETVNLVGLANATVGPQGHPPGLALNAVGLQVLANAPAQSSPAPPAHIQGLQILNIALPTLIPSVGPVAVGTTGTPETTAPNSKAMELQMPAGQGHSAEPPQGSPEGPQETPQTVSGPSADHARPEDSTKMDTKKGPSAGHVLPGRSPAQAQPAPTPEALQKVATSAPPSLPTDRAAPRPPVPHRQPIVHFSDVSSDDDEDRLVIAT", "length": 2688 }, "evidence": [ { "id": "HGNC:4920", "url": "https://alliancegenome.org/gene/HGNC:4920#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-512", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-512#orthology", "database": "AGR" }, { "id": "MGI:96100", "url": "https://alliancegenome.org/gene/MGI:96100#orthology", "database": "AGR" }, { "id": "RGD:727847", "url": "https://alliancegenome.org/gene/RGD:727847#orthology", "database": "AGR" }, { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" }, { "id": "A0A8M9PBC6", "url": "https://omabrowser.org/oma/group/A0A8M9PBC6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3UHF7-1", "protein_name": "Transcription factor HIVEP2", "gene_name": "Hivep2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTGDTALGQKATSRSGETDSVSGRWRQEQSAVLKMSTFSSQEGPRQPQIDPEQIGNAASAQLFGSGKLASPGEGLHQVTEKQYPPHRPSPYPCQHSLSFPQHSLSQGMTHSHKPHQSLEGPPWLFPGPLPSVASEDLFPFPMHGHSGGYPRKKISNLNPAYSQYSQKSIEQAEDAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESSVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKVSPGPPVPLDIASRGGYHGSLEESLGGPMKVPILIIPKSGIPLASEGSQYLSSEMLPNPSLNAKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNTLSVTPTGQERTAMGRRGIMEPLPHLNTRLEVKMFEDPISQLNPSKGEMDPGQINMLKTTKFNSECRQPQAIPSSVRNEGKPYPGNFLGSNPMLLEAPVDSSPLIRSNSMPTSSATNLSVPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHMESEHPARVSKGLASPSLKEKKLLPGDRPGYDYDVCRKPYKKWEDSETLKQSYLGSFKQGGEYFMDPSVPVQGVPTMFGTTCENRKRRKEKSVGDEEDVPMICGGMGNAPVGMMSSEYDPKLQDGGRSGFAMTAHESLAHGHSDRLDPARPQLPSRSPSLGSEDLPLAADPDKMTDLGKKPPGNVISVIQHTNSLSRPNSFERSESTEMVACPQDKTPSPAETCDSEVLEAPVSPEWAPPGDGGESGSKPTPSQQVPQHSYHAQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAPTKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADLEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFDREETVKLTAPPKQDESGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPTEVPEIRSKSFDYGNLSHAPVAGTSPSTLSPSRERKKCFLVRQASFSGSPEIAQGEAGVDPSVKQEHMEHLHAGLRAAWSSVLPPLPGDDPGKQVGTCGPLSSGPPLHLTQQQIMHMDSQESLRNPLIQPTSYMTSKHLPEQPHLFPHQDAVPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQTHFPHPFAPHPQNSYSKPPFQADLHSSYPLEHVAEHTGKKSADYPHAKEQTYPCYSGTSGLHSKNLPLKFPSDPGSKSTETPTEQLLREDFASENAGPLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGLNIAQVLGQHTGLEKYPLWKVPQTLPLGLESSIPLCLPSTSDNAASLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKGLSRPQKPQLVRQGCASEPKDGCFQSRSSSFSSLSPSSSQDHPSASGPFPPNREILPGSRAPPRRKFSGPSESRESSDELDMDETSSDMSMSPQSSALPTGGGQQEEEGKARKLPVSMLVHMASGPGGNVANSTLLFTDVADFQQILQFPSLRTTTTVSWCFLNYTKPSFVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITAEIYTLAAMHRPGAGKLTSSSVWKQFAQMKPDAPFLFGNKLERKLAGNVLKERGKGEIHGDKDLGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDDTETEEAENMEELHKTSEKHSMSGISTDHQFSDAEESDGEDGDDNDDDDEDDDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVAHGVPSDSSLGHSSLISYLVTLPSIQVTQLMTPSDSCDDTQMTEYQRLFQSKSTDSEPDKDRLDIPSSMDEEAMLSSEPSSSPRDFSPSSYRSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQGDASPRRHLSPRRPLSPGKDITARRDLSPRRERRYMTTIRAPSPRRALYPNPPLSMGQYLQTEPIVLGPPNLRRGIPQVPYFSLYGDQEGAYEHHGSSLFPEGPTDYVFSHLPLHSQQQVRAPIPMVPVGGIQMVHSLPPALSGLHPPPTLPLPTEGSEEKKGAPGEAFAKDPYILSRRHEKQAPQVLQSSGLPSSPSSPRLLMKQSTSEDSLNSTEREQEENIQTCTKAIASLRIATEEAALLGADPPTWVQESPQKPLESAHVSIRHFGGPEPGQPCTSAAHPDLHDGEKDTFGTSQTAVAHPTFYSKSSVDEKRVDFQSSKELSLSTEEGNEPSPEKNQLH", "length": 2430 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5T1R4-1", "protein_name": "Transcription factor HIVEP3", "gene_name": "HIVEP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPPNA", "length": 2406 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBC6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1281, "end_pos": 1283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1398, "end_pos": 1400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1789, "end_pos": 1791, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2028, "end_pos": 2030, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2036, "end_pos": 2038, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2369, "end_pos": 2371, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2428, "end_pos": 2430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2441, "end_pos": 2443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 513, "end_pos": 515, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PBC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 352, "end_pos": 379, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PBC6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBC6" }, { "id": "PS51811", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51811" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC HIVEP-type", "eco_id": "ECO_0000259", "start_pos": 899, "end_pos": 929, "start_aa": "Gly", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 88, 317, 2114 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1281, "end_pos": 1283 }, { "start_pos": 1398, "end_pos": 1400 }, { "start_pos": 160, "end_pos": 162 }, { "start_pos": 1789, "end_pos": 1791 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 2028, "end_pos": 2030 }, { "start_pos": 2036, "end_pos": 2038 }, { "start_pos": 2369, "end_pos": 2371 }, { "start_pos": 2428, "end_pos": 2430 }, { "start_pos": 2441, "end_pos": 2443 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 513, "end_pos": 515 }, { "start_pos": 548, "end_pos": 550 }, { "start_pos": 801, "end_pos": 803 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": 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predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021331427", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331427" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJ02", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ02" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101882570", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ02", "locus": {} } ], "crossref": [ { "id": "A0A8M9PJ02", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PJ02", "database": "AlphaFoldDB", "categories": [] }, { "id": "101882570", "url": "https://www.ncbi.nlm.nih.gov/gene/101882570", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:101882570", "url": 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"header": "tr|A0A8M2BFJ7-1|A0A8M9PJ02_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101882570 PE=4 SV=1 CANONICAL=A0A8M9PJ02-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PJ02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ02/entry#A0A8M9PJ02-1", "sequence": { "sequence": "MHINNRNLICVFQHYGALGSCSLKKMYLIVEFIHERSTGPVAKSWYSEGHSWWPPYKEIDRVLKSVRLMEAPQPDKGWTKHQARILHESASFDKISKKWKQACYTSDISESEMPAKRIPKKKIYTSDDEPCDTPHKKKKLNKEKSLPTPRVPLAPKAPTPPRHIRAKGPLVRPQLTSCKTINSFCNSFVRDQQKATEKQQQACFETPSTSQVSAPDVPVRFCQEVEHQDTWDKPQPENQEDTFSVLRPLQDRAPHNTYSVQDPKPSADQRKMQTPVFPISMSHVNEQEDAWGDHPSSYREDTTSELRPSSTQARAKNASGISRWSCISSQYTRK", "length": 334, "header": "tr|A0A8M9PJ02-1|A0A8M9PJ02_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101882570 PE=4 SV=1 CANONICAL=A0A8M9PJ02-1" }, "locus": {} }, { "isoform_ac": "A0AC58JEM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ02/entry#A0AC58JEM3-1", "sequence": { "sequence": "MHINNRNLICVFQHYGALGSCSLKKMYLIVEFIHERSTGPVAKSWYSEGHSWWPPYKEIDRVLKSVRLMEAPQPDKGWTKHQARILHESASFDKISKKWKQACYTSDISESEMPAKRIPKKKIYTSDDEPCDTPHKKKKLNKEKSLPTPRVPLAPKAPTPPRHIRAKGPLVRPQLTSCKTINSFCNSFVRDQQKATEKQQQACFETPSTSQVSAPDVPVRFCQEVEHQDTWDKPQPENQGNSTFSVQSNRGHIFCAAAFTRQSTT", "length": 265, "header": "tr|A0AC58JEM3-1|A0AC58JEM3_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=LOC101882570 PE=4 SV=1 CANONICAL=A0A8M9PJ02-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 159, "start_aa": "Thr", "end_pos": 159, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr159", "evidence": [ { "id": "", "database": "GlyGen", "url": 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}, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z3P0-1", "uniprot_ac": "A0A8M6Z3P0", "uniprot_id": "A0A8M6Z3P0_DANRE", "mass": { "chemical_mass": 121974.0, "monoisotopic_mass": 121974.0 }, "refseq": { "ac": "XP_017208298", "name": "ubiquitin-associated protein 2a isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208298" }, "gene_names": [ { "name": "ubap2a", "type": "recommended", "evidence": [ { "id": "A0A8M6Z3P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0" } ] }, { "name": "ubap2a", "type": "synonym", "evidence": [ { "id": "XP_017208298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208298" } ] }, { "name": "ubap2", "type": "synonym", "evidence": [ { "id": "XP_017208298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208298" }, { "id": "A0A8M6Z3P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0" } ] }, { "name": "zgc:158449", "type": "synonym", "evidence": [ { "id": "XP_017208298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208298" }, { "id": "A0A8M6Z3P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0" } ] } ], "protein_names": [ { "name": "Ubiquitin-associated protein 2a isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z3P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0/entry#names_and_taxonomy" } ] }, { "name": "ubiquitin-associated protein 2a isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017208298", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208298" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017208298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208298" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3P0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ubap2a", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070424-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-16", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z3P0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z3P0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14277", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14277", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "563733", "url": "https://www.ncbi.nlm.nih.gov/gene/563733", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022166", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022166", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051833", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051833", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060532", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060532", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:563733", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563733", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M2B877", "url": "https://www.orthodb.org/?gene=A0A8M2B877", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AM03", "url": "https://www.orthodb.org/?gene=A0A8M3AM03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3B4J7", "url": "https://www.orthodb.org/?gene=A0A8M3B4J7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YUH8", "url": "https://www.orthodb.org/?gene=A0A8M6YUH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z309", "url": "https://www.orthodb.org/?gene=A0A8M6Z309", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z3P0", "url": "https://www.orthodb.org/?gene=A0A8M6Z3P0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16308:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16308:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12478", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12478", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28540", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28540", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017208298", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208298", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M1NC12", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NC12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1NC12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NC12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B877", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B877", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B877-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B877-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AM03", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AM03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AM03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AM03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B4J7", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B4J7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B4J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B4J7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YUH8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YUH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YUH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YUH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z309", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z309", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z309-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z309-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3P0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I9M6", "url": "https://www.uniprot.org/uniprotkb/A0AC58I9M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I9M6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I9M6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I9N0", "url": "https://www.uniprot.org/uniprotkb/A0AC58I9N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I9N0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I9N0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I9P2", "url": "https://www.uniprot.org/uniprotkb/A0AC58I9P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I9P2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I9P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070424-16", "url": "https://zfin.org/ZDB-GENE-070424-16", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMSSVGVERARGTRDKALPTTTQTTQPQKQLQATAEQIRLAQMIYDKNDADFEDKVKQLMEVTGKNQDDCMVALHDCNEDVNRAINFLLEGTSDATSWETVGKKKSIGKDGPSSESKENKENREKKERESSKGRGGPSRRGRGTSRNRPARTEENGVDPAPVERGADRGRRGRGRVSGGRGRGRAPATSRFTAQGMGTFNPADYTTDSGTSNSHADVWETGANDTTDGTVAWQNTLDEWAAEDWSEDVSLSETKVFTSSCAPPTENHITPGQSLDLSTLLQKPVDREEVGGLKAVGSSQGLGHSLVFTNSHHQPARNGGTPAGSNSYTHATLSSVLGSGFGELGGPKLGQTAGQQILEQLKGPGLGQLTSQPSSTGTNCTPVGGLVGTGMSVPSSSWDIKPPGTQSSTSLPSQFSREFQMQPEPSLVLSQLAQRQQSSLTHTGPLARQPSPPPLSTPSTAQGTLEAFPKAPEPSQHRDGPSMAPSQTGDSQGSSTQQRQIKTQKRRIPPTSKIPASAVEMPGSADVSGLNVQFGALDFGSESALPDFSQSENCSSEPIRETAVVSQSQSSLYSKPISESLSSPVPLLLPLASSDSIYPSPSVPLPSLAPSHSTPSSATAPSSSSSSSSSSAASSAGNSFDCGVAPHSRLTFSQSKEPSGPVTNGFNGARTSAALDTTSSSSTPKQESPSLVSNTSVAPSAPSSLLPSSVTPHSSALPSLASELSSASLPPLSSHVSSGHPSVSALCTTSSHTYTSVDSVNSLAPSSMAFSSPPVSALASSSMNNSVSGGNSLHGPGVLGHGPNGSTPSAVRTAQLLSSSSGKAPPNLSQGVPPLLPNQYIMGPGGLLPAYPQIYGYEDLHMLQSRLPMDYYGITFPGPTAPLSGRDGSLASNPYSGDVTKFGRGESTSPAPSSSLSAAHAPQTAQPPQAQSQGQNQPQPQGHHNTQQPFLNPALPPGYSYTGLPYYPGVPGVPSAFQYGPTMFVPPASAKQHGMGLSNPTTPFQQPSGYGQHAFSSGYDDLTQGPAGSDYSKGYSNSSQTQAKSAASGPGKGTDMRIPGVSVTSSNSGVPDISGTVYNKTQPFEKQGFHAGTPPPFNLPSALGGTGPLTPGAAPGYAPAPFLHILPAHQQPHSQLLHHHLTQDGQGGPSQRSQSSTMQQKTQVNKSNYGSSPYWGN", "length": 1176, "header": "tr|A0A8M6Z3P0-1|A0A8M6Z3P0_DANRE Isoform 1 of Ubiquitin-associated protein 2a isoform X1 OS=Danio rerio OX=7955 GN=ubap2a PE=1 SV=1 CANONICAL=A0A8M6Z3P0-1" }, "isoforms": [ { "isoform_ac": "A0A8M1NC12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0/entry#A0A8M1NC12-1", "sequence": { "sequence": "MMSSVGVERARGTRDKALPTTTQTTQPQKQLQATAEQIRLAQMIYDKNDADFEDKVKQLMEVTGKNQDDCMVALHDCNEDVNRAINFLLEGTSDATSWETVGKKKSIGKDGPSSESKENKENREKKERESSKGRGGPSRRGRGTSRNRPARTEENGVDPAPVERGADRGRRGRGRVSGGRGRGRAPATSRFTAQGMGTFNPADYTTDSGTSNSHADVWETGANDTTDGTVAWQNTLDEWAAEDWSEDVSLSETKVFTSSCAPPTENHITPGQSLDLSTLLQKPVDREEVGGLKAVGSSQGLGHSLVFTNSHHQPARNGGTPAGSNSYTHATLSSVLGSGFGELGGPKLGQTAGQQILEQLKGPGLGQLTSQPSSTGTNCTPVGGLVGTGMSVPSSSWDIKPPGTQSSTSLPSQFSREFQMQPEPSLVLSQLAQRQQSSLTHTGPLARQPSPPPLSTPSTAQGTLEAFPKAPEPSQHRDGPSMAPSQTGDSQGSSTQQRQIKTQKRRIPPTSKIPASAVEMPGSADVSGLNVQFGALDFGSESALPDFSQSENCSSEPIRETAVVSQSQSSLYSKPISESLSSPVPLLLPLASSDSIYPSPSVPLPSLAPSHSTPSSATAPSSSSSSSSSSAASSAGNSFDCGVAPHSRLTFSQSKEPSGPVTNGFNGARTSAALDTTSSSSTPKQESPSLVSNTSVAPSAPSSLLPSSVTPHSSALPSLASELSSASLPPLSSHVSSGHPSVSALCTTSSHTYTSVDSVNSLAPSSMAFSSPPVSALASSSMNNSVSGGNSLHGPGVLGHGPNGSTPSAVRTAQLLSSSSGKAPPNLSQGVPPLLPNQYIMGPGGLLPAYPQIYGYEDLHMLQSRLPMDYYGITFPGPTAPLSGRDGSLASNPYSGDVTKFGRGESTSPAPSSSLSAAHAPQTAQPPQAQSQGQNQPQPQGHHNTQQPFLNPALPPGYSYTGLPYYPGVPGVPSAFQYGPTMFVPPASAKQHGMGLSNPTTPFQQPSGYGQHAFSSGYDDLTQGPAGSDYSKGYSNSSQTQAKSAASGPGKGVSVTSSNSGVPDISGTVYNKTQPFEKQGFHAGTPPPFNLPSALGGTGPLTPGAAPGYAPAPFLHILPAHQQPHSQLLHHHLTQDGQGGPSQRSQSSTMQQKTQVNKSNYGSSPYWGN", "length": 1169, "header": "tr|A0A8M1NC12-1|A0A8M6Z3P0_DANRE Computationally mapped isoform of Ubiquitin-associated protein 2a isoform X1 OS=Danio rerio OX=7955 GN=ubap2a PE=1 SV=1 CANONICAL=A0A8M6Z3P0-1" }, "locus": {} }, { "isoform_ac": "A0A8M2B877-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0/entry#A0A8M2B877-1", "sequence": { "sequence": "MMSSVGVERARGTRDKALPTTTQTTQPQKQLQATAEQIRLAQMIYDKNDADFEDKVKQLMEVTGKNQDDCMVALHDCNEDVNRAINFLLEGTSDATSWETVGKKKSIGKDGPSSESKENKENREKKERESSKGRGGPSRRGRGTSRNRPARTEENGVDPAPVERGADRGRRGRGRVSGGRGRGRAPATSRFTAQGMGTFNPADYTTDSGTSNSHADVWETGANDTTDGTVAWQNTLDEWAAEDWSEDVSLSETKVFTSSCAPPTENHITPGQSLDLSTLLQKPVDREEVGGLKAVGSSQGLGHSLVFTNSHHQPARNGGTPAGSNSYTHATLSSVLGSGFGELGGPKLGQTAGQQILEQLKGPGLGQLTSQPSSTGTNCTPVGGLVGTGMSVPSSSWDIKPPGTQSSTSLPSQFSREFQMQPEPSLVLSQLAQRQQSSLTHTGPLARQPSPPPLSTPSTAQGTLEAFPKAPEPSQHRDGPSMAPSQTGDSQGSSTQQRQIKTQKRRIPPTSKIPASAVEMPGSADVSGLNVQFGALDFGSESALPDFSQSENCSSEPIRETAVVSQSQSSLYSKPISESLSSPVPLLLPLASSDSIYPSPSVPLPSLAPSHSTPSSATAPSSSSSSSSSSAASSAGNSFDCGVAPHSRLTFSQSKEPSGPVTNGFNGARTSAALDTTSSSSTPKQESPSLVSNTSVAPSAPSSLLPSSVTPHSSALPSLASELSSASLPPLSSHVSSGHPSVSALCTTSSHTYTSVDSVNSLAPSSMAFSSPPVSALASSSMNNSVSGGNSLHGPGVLGHGPNGSTPSAVRTAQLLSSSSGKAPPNLSQGVPPLLPNQYIMGPGGLLPAYPIYGYEDLHMLQSRLPMDYYGITFPGPTAPLSGRDGSLASNPYSGDVTKFGRGESTSPAPSSSLSAAHAPQTAQPPQAQSQGQNQPQPQGHHNTQQPFLNPALPPGYSYTGLPYYPGVPGVPSAFQYGPTMFVPPASAKQHGMGLSNPTTPFQQPSGYGQHAFSSGYDDLTQGPAGSDYSKGYSNSSQTQAKSAASGPGKGVSVTSSNSGVPDISGTVYNKTQPFEKQGFHAGTPPPFNLPSALGGTGPLTPGAAPGYAPAPFLHILPAHQQPHSQLLHHHLTQDGQGGPSQRSQSSTMQQKTQVNKSNYGSSPYWGN", "length": 1168, "header": "tr|A0A8M2B877-1|A0A8M6Z3P0_DANRE Computationally mapped isoform of Ubiquitin-associated protein 2a isoform X1 OS=Danio rerio OX=7955 GN=ubap2a PE=1 SV=1 CANONICAL=A0A8M6Z3P0-1" }, "locus": {} }, { "isoform_ac": "A0A8M3AM03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0/entry#A0A8M3AM03-1", "sequence": { "sequence": "MMSSVGVERARGTRDKALPTTTQTTQPQKQLQATAEQIRLAQMIYDKNDADFEDKVKQLMEVTGKNQDDCMVALHDCNEDVNRAINFLLEGTSDATSWETVGKKKSIGKDGPSSESKENKENREKKERESSKGRGGPSRRGRGTSRNRPARTEENGVDPAPVERGADRGRRGRGRVSGGRGRGRAPATSRFTAQGMGTFNPADYTTDSGTSNSHADVWETGANDTTDGTVAWQNTLDEWAAEDWSEDLSETKVFTSSCAPPTENHITPGQSLDLSTLLQKPVDREEVGGLKAVGSSQGLGHSLVFTNSHHQPARNGGTPAGSNSYTHATLSSVLGSGFGELGGPKLGQTAGQQILEQLKGPGLGQLTSQPSSTGTNCTPVGGLVGTGMSVPSSSWDIKPPGTQSSTSLPSQFSREFQMQPEPSLVLSQLAQRQQSSLTHTGPLARQPSPPPLSTPSTAQGTLEAFPKAPEPSQHRDGPSMAPSQTGDSQGSSTQQRQIKTQKRRIPPTSKIPASAVEMPGSADVSGLNVQFGALDFGSESALPDFSQSENCSSEPIRETAVVSQSQSSLYSKPISESLSSPVPLLLPLASSDSIYPSPSVPLPSLAPSHSTPSSATAPSSSSSSSSSSAASSAGNSFDCGVAPHSRLTFSQSKEPSGPVTNGFNGARTSAALDTTSSSSTPKQESPSLVSNTSVAPSAPSSLLPSSVTPHSSALPSLASELSSASLPPLSSHVSSGHPSVSALCTTSSHTYTSVDSVNSLAPSSMAFSSPPVSALASSSMNNSVSGGNSLHGPGVLGHGPNGSTPSAVRTAQLLSSSSGKAPPNLSQGVPPLLPNQYIMGPGGLLPAYPIYGYEDLHMLQSRLPMDYYGITFPGPTAPLSGRDGSLASNPYSGDVTKFGRGESTSPAPSSSLSAAHAPQTAQPPQAQSQGQNQPQPQGHHNTQQPFLNPALPPGYSYTGLPYYPGVPGVPSAFQYGPTMFVPPASAKQHGMGLSNPTTPFQQPSGYGQHAFSSGYDDLTQGPAGSDYSKGYSNSSQTQAKSAASGPGKGVSVTSSNSGVPDISGTVYNKTQPFEKQGFHAGTPPPFNLPSALGGTGPLTPGAAPGYAPAPFLHILPAHQQPHSQLLHHHLTQDGQGGPSQRSQSSTMQQKTQVNKSNYGSSPYWGN", "length": 1166, "header": "tr|A0A8M3AM03-1|A0A8M6Z3P0_DANRE Computationally mapped isoform of Ubiquitin-associated protein 2a isoform X1 OS=Danio rerio OX=7955 GN=ubap2a PE=1 SV=1 CANONICAL=A0A8M6Z3P0-1" }, "locus": {} }, { "isoform_ac": "A0A8M3B4J7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0/entry#A0A8M3B4J7-1", "sequence": { "sequence": "MMSSVGVERARGTRDKALPTTTQTTQPQKQLQATAEQIRLAQMIYDKNDADFEDKVKQLMEVTGKNQDDCMVALHDCNEDVNRAINFLLEGTSDATSWETVGKKKSIGKDGPSSESKENKENREKKERESSKGRGGPSRRGRGTSRNRPARTEENGVDPAPVERGADRGRRGRGRVSGGRGRGRAPATSRFTAQGMGTFNPADYTTDSGTSNSHADVWETGANDTTDGTVAWQNTLDEWAAEDWSEDLSETKVFTSSCAPPTENHITPGQSLDLSTLLQKPVDREEVGGLKAVGSSQGLGHSLVFTNSHHQPARNGGTPAGSNSYTHATLSSVLGSGFGELGGPKLGQTAGQQILEQLKGPGLGQLTSQPSSTGTNCTPVGGLVGTGMSVPSSSWDIKPPGTQSSTSLPSQFSREFQMQPEPSLVLSQLAQRQQSSLTHTGPLARQPSPPPLSTPSTAQGTLEAFPKAPEPSQHRDGPSMAPSQTGDSQGSSTQQRQIKTQKRRIPPTSKIPASAVEMPGSADVSGLNVQFGALDFGSESALPDFSQSENCSSEPIRETAVVSQSQSSLYSKPISESLSSPVPLLLPLASSDSIYPSPSVPLPSLAPSHSTPSSATAPSSSSSSSSSSAASSAGNSFDCGVAPHSRLTFSQSKEPSGPVTNGFNGARTSAALDTTSSSSTPKQESPSLVSNTSVAPSAPSSLLPSSVTPHSSALPSLASELSSASLPPLSSHVSSGHPSVSALCTTSSHTYTSVDSVNSLAPSSMAFSSPPVSALASSSMNNSVSGGNSLHGPGVLGHGPNGSTPSAVRTAQLLSSSSGKAPPNLSQGVPPLLPNQYIMGPGGLLPAYPQIYGYEDLHMLQSRLPMDYYGITFPGPTAPLSGRDGSLASNPYSGDVTKFGRGESTSPAPSSSLSAAHAPQTAQPPQAQSQGQNQPQPQGHHNTQQPFLNPALPPGYSYTGLPYYPGVPGVPSAFQYGPTMFVPPASAKQHGMGLSNPTTPFQQPSGYGQHAFSSGYDDLTQGPAGSDYSKGYSNSSQTQAKSAASGPGKGVSVTSSNSGVPDISGTVYNKTQPFEKQGFHAGTPPPFNLPSALGGTGPLTPGAAPGYAPAPFLHILPAHQQPHSQLLHHHLTQDGQGGPSQRSQSSTMQQKTQVNKSNYGSSPYWGN", "length": 1167, "header": "tr|A0A8M3B4J7-1|A0A8M6Z3P0_DANRE Computationally mapped isoform of Ubiquitin-associated protein 2a isoform X1 OS=Danio rerio OX=7955 GN=ubap2a PE=1 SV=1 CANONICAL=A0A8M6Z3P0-1" }, "locus": {} }, { "isoform_ac": "A0A8M6YUH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0/entry#A0A8M6YUH8-1", "sequence": { "sequence": "MMSSVGVERARGTRDKALPTTTQTTQPQKQLQATAEQIRLAQMIYDKNDADFEDKVKQLMEVTGKNQDDCMVALHDCNEDVNRAINFLLEGTSDATSWETVGKKKSIGKDGPSSESKENKENREKKERESSKGRGGPSRRGRGTSRNRPARTEENGVDPAPVERGADRGRRGRGRVSGGRGRGRAPATSRFTAQGMGTFNPADYTTDSGTSNSHADVWETGANDTTDGTVAWQNTLDEWAAEDWSEDVSLSETKVFTSSCAPPTENHITPGQSLDLSTLLQKPVDREEVGGLKAVGSSQGLGHSLVFTNSHHQPARNGGTPAGSNSYTHATLSSVLGSGFGELGGPKLGQTAGQQILEQLKGPGLGQLTSQPSSTGTNCTPVGGLVGTGMSVPSSSWDIKPPGTQSSTSLPSQFSREFQMQPEPSLVLSQLAQRQQSSLTHTGPLARQPSPPPLSTPSTAQGTLEAFPKAPEPSQHRDGPSMAPSQTGDSQGSSTQQRQIKTQKRRIPPTSKIPASAVEMPGSADVSGLNVQFGALDFGSESALPDFSQSENCSSEPIRETAVVSQSQSSLYSKPISESLSSPVPLLLPLASSDSIYPSPSVPLPSLAPSHSTPSSATAPSSSSSSSSSSAASSAGNSFDCGVAPHSRLTFSQSKEPSGPVTNGFNGARTSAALDTTSSSSTPKQESPSLVSNTSVAPSAPSSLLPSSVTPHSSALPSLASELSSASLPPLSSHVSSGHPSVSALCTTSSHTYTSVDSVNSLAPSSMAFSSPPVSALASSSMNNSVSGGNSLHGPGVLGHGPNGSTPSAVRTAQLLSSSSGKAPPNLSQGVPPLLPNQYIMGPGGLLPAYPIYGYEDLHMLQSRLPMDYYGITFPGPTAPLSGRDGSLASNPYSGDVTKFGRGESTSPAPSSSLSAAHAPQTAQPPQAQSQGQNQPQPQGHHNTQQPFLNPALPPGYSYTGLPYYPGVPGVPSAFQYGPTMFVPPASAKQHGMGLSNPTTPFQQPSGYGQHAFSSGYDDLTQGPAGSDYSKGYSNSSQTQAKSAASGPGKGTDMRIPGVSVTSSNSGVPDISGTVYNKTQPFEKQGFHAGTPPPFNLPSALGGTGPLTPGAAPGYAPAPFLHILPAHQQPHSQLLHHHLTQDGQGGPSQRSQSSTMQQKTQVNKSNYGSSPYWGN", "length": 1175, "header": "tr|A0A8M6YUH8-1|A0A8M6Z3P0_DANRE Computationally mapped isoform of Ubiquitin-associated protein 2a isoform X1 OS=Danio rerio OX=7955 GN=ubap2a PE=1 SV=1 CANONICAL=A0A8M6Z3P0-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z309-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0/entry#A0A8M6Z309-1", "sequence": { "sequence": "MMSSVGVERARGTRDKALPTTTQTTQPQKQLQATAEQIRLAQMIYDKNDADFEDKVKQLMEVTGKNQDDCMVALHDCNEDVNRAINFLLEGTSDATSWETVGKKKSIGKDGPSSESKENKENREKKERESSKGRGGPSRRGRGTSRNRPARTEENGVDPAPVERGADRGRRGRGRVSGGRGRGRAPATSRFTAQGMGTFNPADYTTDSGTSNSHADVWETGANDTTDGTVAWQNTLDEWAAEDWSEDLSETKVFTSSCAPPTENHITPGQSLDLSTLLQKPVDREEVGGLKAVGSSQGLGHSLVFTNSHHQPARNGGTPAGSNSYTHATLSSVLGSGFGELGGPKLGQTAGQQILEQLKGPGLGQLTSQPSSTGTNCTPVGGLVGTGMSVPSSSWDIKPPGTQSSTSLPSQFSREFQMQPEPSLVLSQLAQRQQSSLTHTGPLARQPSPPPLSTPSTAQGTLEAFPKAPEPSQHRDGPSMAPSQTGDSQGSSTQQRQIKTQKRRIPPTSKIPASAVEMPGSADVSGLNVQFGALDFGSESALPDFSQSENCSSEPIRETAVVSQSQSSLYSKPISESLSSPVPLLLPLASSDSIYPSPSVPLPSLAPSHSTPSSATAPSSSSSSSSSSAASSAGNSFDCGVAPHSRLTFSQSKEPSGPVTNGFNGARTSAALDTTSSSSTPKQESPSLVSNTSVAPSAPSSLLPSSVTPHSSALPSLASELSSASLPPLSSHVSSGHPSVSALCTTSSHTYTSVDSVNSLAPSSMAFSSPPVSALASSSMNNSVSGGNSLHGPGVLGHGPNGSTPSAVRTAQLLSSSSGKAPPNLSQGVPPLLPNQYIMGPGGLLPAYPQIYGYEDLHMLQSRLPMDYYGITFPGPTAPLSGRDGSLASNPYSGDVTKFGRGESTSPAPSSSLSAAHAPQTAQPPQAQSQGQNQPQPQGHHNTQQPFLNPALPPGYSYTGLPYYPGVPGVPSAFQYGPTMFVPPASAKQHGMGLSNPTTPFQQPSGYGQHAFSSGYDDLTQGPAGSDYSKGYSNSSQTQAKSAASGPGKGTDMRIPGVSVTSSNSGVPDISGTVYNKTQPFEKQGFHAGTPPPFNLPSALGGTGPLTPGAAPGYAPAPFLHILPAHQQPHSQLLHHHLTQDGQGGPSQRSQSSTMQQKTQVNKSNYGSSPYWGN", "length": 1174, "header": "tr|A0A8M6Z309-1|A0A8M6Z309_DANRE Computationally mapped isoform of Ubiquitin-associated protein 2a isoform X3 OS=Danio rerio OX=7955 GN=ubap2a PE=1 SV=1 CANONICAL=A0A8M6Z3P0-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z3P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0/entry#A0A8M6Z3P0-1", "sequence": { "sequence": "MMSSVGVERARGTRDKALPTTTQTTQPQKQLQATAEQIRLAQMIYDKNDADFEDKVKQLMEVTGKNQDDCMVALHDCNEDVNRAINFLLEGTSDATSWETVGKKKSIGKDGPSSESKENKENREKKERESSKGRGGPSRRGRGTSRNRPARTEENGVDPAPVERGADRGRRGRGRVSGGRGRGRAPATSRFTAQGMGTFNPADYTTDSGTSNSHADVWETGANDTTDGTVAWQNTLDEWAAEDWSEDVSLSETKVFTSSCAPPTENHITPGQSLDLSTLLQKPVDREEVGGLKAVGSSQGLGHSLVFTNSHHQPARNGGTPAGSNSYTHATLSSVLGSGFGELGGPKLGQTAGQQILEQLKGPGLGQLTSQPSSTGTNCTPVGGLVGTGMSVPSSSWDIKPPGTQSSTSLPSQFSREFQMQPEPSLVLSQLAQRQQSSLTHTGPLARQPSPPPLSTPSTAQGTLEAFPKAPEPSQHRDGPSMAPSQTGDSQGSSTQQRQIKTQKRRIPPTSKIPASAVEMPGSADVSGLNVQFGALDFGSESALPDFSQSENCSSEPIRETAVVSQSQSSLYSKPISESLSSPVPLLLPLASSDSIYPSPSVPLPSLAPSHSTPSSATAPSSSSSSSSSSAASSAGNSFDCGVAPHSRLTFSQSKEPSGPVTNGFNGARTSAALDTTSSSSTPKQESPSLVSNTSVAPSAPSSLLPSSVTPHSSALPSLASELSSASLPPLSSHVSSGHPSVSALCTTSSHTYTSVDSVNSLAPSSMAFSSPPVSALASSSMNNSVSGGNSLHGPGVLGHGPNGSTPSAVRTAQLLSSSSGKAPPNLSQGVPPLLPNQYIMGPGGLLPAYPQIYGYEDLHMLQSRLPMDYYGITFPGPTAPLSGRDGSLASNPYSGDVTKFGRGESTSPAPSSSLSAAHAPQTAQPPQAQSQGQNQPQPQGHHNTQQPFLNPALPPGYSYTGLPYYPGVPGVPSAFQYGPTMFVPPASAKQHGMGLSNPTTPFQQPSGYGQHAFSSGYDDLTQGPAGSDYSKGYSNSSQTQAKSAASGPGKGTDMRIPGVSVTSSNSGVPDISGTVYNKTQPFEKQGFHAGTPPPFNLPSALGGTGPLTPGAAPGYAPAPFLHILPAHQQPHSQLLHHHLTQDGQGGPSQRSQSSTMQQKTQVNKSNYGSSPYWGN", "length": 1176, "header": "tr|A0A8M6Z3P0-1|A0A8M6Z3P0_DANRE Isoform 1 of Ubiquitin-associated protein 2a isoform X1 OS=Danio rerio OX=7955 GN=ubap2a PE=1 SV=1 CANONICAL=A0A8M6Z3P0-1" }, "locus": {} }, { "isoform_ac": "A0AC58I9M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0/entry#A0AC58I9M6-1", "sequence": { "sequence": "MMSSVGVERARGTRDKALPTTTQTTQPQKQLQATAEQIRLAQMIYDKNDADFEDKVKQLMEVTGKNQDDCMVALHDCNEDVNRAINFLLEGTSDATSWETVGKKKSIGKDGPSSESKENKENREKKERESSKGRGGPSRRGRGTSRNRPARTEENGVDPAPVERGADRGRRGRGRVSGGRGRGRAPATSRFTAQGMGTFNPADYTTDSGTSNSHADVWETGANDTTDGTVAWQNTLDEWAAEDWSEDVSLSETKVFTSSCAPPTENHITPGQSLDLSTLLQKPVDREEVGGLKAVGSSQGLGHSLVFTNSHHQPARNGGTPAGSNSYTHATLSSVLGSGFGELGGPKLGQTAGQQILEQLKGPGLGQLTSQPSSTGTNCTPVGGLVGTGMSVPSSSWDIKPPGTQSSTSLPSQFSREFQMQPEPSLVLSQLAQRQQSSLTHTGPLARQPSPPPLSTPSTAQGTLEAFPKAPEPSQHRDGPSMAPSQTGDSQGSSTQQRQIKTQKRRIPPTSKIPASAVEMPGSADVSGLNVQFGALDFGSESALPDFSQSENCSSEPIRETAVVSQSQSSLYSKPISESLSSPVPLLLPLASSDSIYPSPSVPLPSLAPSHSTPSSATAPSSSSSSSSSSAASSAGNSFDCGVAPHSRLTFSQSKEPSGPVTNGFNGARTSAALDTTSSSSTPKQESPSLVSNTSVAPSAPSSLLPSSVTPHSSALPSLASELSSASLPPLSRYFCVLLQEHANSTQKCQLTRLRLELVTFLL", "length": 763, "header": "tr|A0AC58I9M6-1|A0AC58I9M6_DANRE Computationally mapped isoform of Ubiquitin-associated protein 2a isoform X8 OS=Danio rerio OX=7955 GN=ubap2a PE=1 SV=1 CANONICAL=A0A8M6Z3P0-1" }, "locus": {} }, { "isoform_ac": "A0AC58I9N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0/entry#A0AC58I9N0-1", "sequence": { "sequence": "MMSSVGVERARGTRDKALPTTTQTTQPQKQLQATAEQIRLAQMIYDKNDADFEDKVKQLMEVTGKNQDDCMVALHDCNEDVNRAINFLLEGTSDATSWETVGKKKSIGKDGPSSESKENKENREKKERESSKGRGGPSRRGRGTSRNRPARTEENGVDPAPVERGADRGRRGRGRVSGGRGRGRAPATSRFTAQGMGTFNPADYTTDSGTSNSHADVWETGANDTTDGTVAWQNTLDEWAAEDWSEDLSETKVFTSSCAPPTENHITPGQSLDLSTLLQKPVDREEVGGLKAVGSSQGLGHSLVFTNSHHQPARNGGTPAGSNSYTHATLSSVLGSGFGELGGPKLGQTAGQQILEQLKGPGLGQLTSQPSSTGTNCTPVGGLVGTGMSVPSSSWDIKPPGTQSSTSLPSQFSREFQMQPEPSLVLSQLAQRQQSSLTHTGPLARQPSPPPLSTPSTAQGTLEAFPKAPEPSQHRDGPSMAPSQTGDSQGSSTQQRQIKTQKRRIPPTSKIPASAVEMPGSADVSGLNVQFGALDFGSESALPDFSQSENCSSEPIRETAVVSQSQSSLYSKPISESLSSPVPLLLPLASSDSIYPSPSVPLPSLAPSHSTPSSATAPSSSSSSSSSSAASSAGNSFDCGVAPHSRLTFSQSKEPSGPVTNGFNGARTSAALDTTSSSSTPKQESPSLVSNTSVAPSAPSSLLPSSVTPHSSALPSLASELSSASLPPLSRYFCVLLQEHANSTQKCQLTRLRLELVTFLL", "length": 761, "header": "tr|A0AC58I9N0-1|A0AC58I9N0_DANRE Computationally mapped isoform of Ubiquitin-associated protein 2a isoform X9 OS=Danio rerio OX=7955 GN=ubap2a PE=1 SV=1 CANONICAL=A0A8M6Z3P0-1" }, "locus": {} }, { "isoform_ac": "A0AC58I9P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0/entry#A0AC58I9P2-1", "sequence": { "sequence": "MMSSVGVERARGTRDKALPTTTQTTQPQKQLQATAEQIRLAQMIYDKNDADFEDKVKQLMEVTGKNQDDCMVALHDCNEDVNRAINFLLEGTSDATSWETVGKKKSIGKDGPSSESKENKENREKKERESSKGRGGPSRRGRGTSRNRPARTEENGVDPAPVERGADRGRRGRGRVSGGRGRGRAPATSRFTAQGMGTFNPADYTTDSGTSNSHADVWETGANDTTDGTVAWQNTLDEWAAEDWSEDLSETKVFTSSCAPPTENHITPGQSLDLSTLLQKPVDREEVGGLKAVGSSQGLGHSLVFTNSHHQPARNGGTPAGSNSYTHATLSSVLGSGFGELGGPKLGQTAGQQILEQLKGPGLGQLTSQPSSTGTNCTPVGGLVGTGMSVPSSSWDIKPPGTQSSTSLPSQFSREFQMQPEPSLVLSQLAQRQQSSLTHTGPLARQPSPPPLSTPSTAQGTLEAFPKAPEPSQHRDGPSMAPSQTGDSQGSSTQQRQIKTQKRRIPPTSKIPASAVEMPGSADVSGLNVQFGALDFGSESALPDFSQSENCSSEPIRETAVVSQSQSSLYSKPISESLSSPVPLLLPLASSDSIYPSPSVPLPSLAPSHSTPSSATAPSSSSSSSSSSAASSAGNSFDCGVAPHSRLTFSQSKEPSGPVTNGFNGARTSAALDTTSSSSTPKQESPSLVSNTSVAPSAPSSLLPSSVTPHSSALPSLASELSSASLPPLSSHVSSGHPSVSALCTTSSHTYTSVDSVNSLAPSSMAFSSPPVSALASSSMNNSVSGGNSLHGPGVLGHGPNGSTPSAVRTAQLLSSSSGKAPPNLSQGVPPLLPNQYIMGPGGLLPAYPIYGYEDLHMLQSRLPMDYYGITFPGPTAPLSGRDGSLASNPYSGDVTKFGRGESTSPAPSSSLSAAHAPQTAQPPQAQSQGQNQPQPQGHHNTQQPFLNPALPPGYSYTGLPYYPGVPGVPSAFQYGPTMFVPPASAKQHGMGLSNPTTPFQQPSGYGQHAFSSGYDDLTQGPAGSDYSKGYSNSSQTQAKSAASGPGKGTDMRIPGVSVTSSNSGVPDISGTVYNKTQPFEKQGFHAGTPPPFNLPSALGGTGPLTPGAAPGYAPAPFLHILPAHQQPHSQLLHHHLTQDGQGGPSQRSQSSTMQQKTQVNKSNYGSSPYWGN", "length": 1173, "header": "tr|A0AC58I9P2-1|A0AC58I9P2_DANRE Computationally mapped isoform of Ubiquitin-associated protein 2a isoform X4 OS=Danio rerio OX=7955 GN=ubap2a PE=1 SV=1 CANONICAL=A0A8M6Z3P0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 456, "start_aa": "Thr", "end_pos": 456, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr456", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 806, "start_aa": "Thr", "end_pos": 806, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr806", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 879, "start_aa": "Thr", "end_pos": 879, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr879", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment.", "journal": "Nat. Commun.", "date": "2013", "authors": "Baraban Scott C, Dinday Matthew T, Hortopan Gabriela A", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1NC12", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NC12" } ], "reference": [ { "type": "PubMed", "id": "24002024", "url": "https://glygen.org/publication/PubMed/24002024" } ] }, { "title": "Xmrk, kras and myc transgenic zebrafish liver cancer models share molecular signatures with subsets of human hepatocellular carcinoma.", "journal": "PLoS ONE", "date": "2014", "authors": "Zheng Weiling, Li Zhen, Nguyen Anh Tuan, Li Caixia, Emelyanov Alexander, Gong Zhiyuan", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1NC12", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NC12" } ], "reference": [ { "type": "PubMed", "id": "24633177", "url": "https://glygen.org/publication/PubMed/24633177" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1NC12", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NC12" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1NC12", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NC12" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "UBAP2 plays a role in bone homeostasis through the regulation of osteoblastogenesis and osteoclastogenesis.", "journal": "Nat. Commun.", "date": "2023", "authors": "Kim Jeonghyun, Kim Bo-Young, Lee Jeong-Soo, Jeong Yun-Mi, Cho Hyun-Ju, Park Eunkuk, Kim Dowan, Kim Sung-Soo, Kim Bom-Taeck, Choi Yong Jun, Won Ye-Yeon, Jin Hyun-Seok, Chung Yoon-Sok, Jeong Seon-Yong", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1NC12", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NC12" } ], "reference": [ { "type": "PubMed", "id": "37339951", "url": "https://glygen.org/publication/PubMed/37339951" } ] } ], "pathway": [ { "id": "dre:563733", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563733", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0U1RRQ3-1", "protein_name": "Ubiquitin-associated protein 2", "gene_name": "Ubap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVAEVLGKNHRCQQHTQHSHRNKWYSCTDLLTLLELSLATAEQMRLAQVIFDKNDSDFEAKVKQLMEVTGKNQDECIVALHDCNGDVNKAINTLLEGSSDTTSWETVGGKKKNFGRESSENKENREKRTEREASRGRGNNNRKGRGGSRGREFKGEENGVDCSQGDKPSERGKRTRGRGFGRGRGRGAGRLSAQSMGTFNPADYSESMSTDGCGTKLVVWEAAQNGTDEGPEGLAKPHSISQELPSKSSYGLKGAWKNSVEEWTAEDWTEDLSETKVFTASSAPADNHVPPGQSIDLVALLHKPAPPTQAAEVNSFETSQQQGFGQALVFTNSQHNNPTAPGTASSTPASSYSPQSLSSVLGSGFGELAQSKMVNISNSQILDKLKPPGLSPFPAASSTQQNDNASPPATTAAWDLKPSAPQPSVLSHLDFKSQPEPSPVLSQLSQRQQQQNQAVSVPPPGLESFPSQTKHRESAPGDGPSTVNRLLQLPTMAVENIVSAHQPQPKHIKLPKRRIPPASKVPVSAVEMPGSADITGLNVQFGALEFGSEPSLSEFGSTASASENSSQLPISLYPKSLSEPLNASFPMTSAVQNPTYTTSVITSSTLTSSSVSSTSPVTTCSSYDQSSVHTRIAYQSPASPADAAPGSVANGHGGGRSQHTVDTTSSVPAPKKTDPSALPSVSSLPSPSSCTALLPPSSQHTATLPALTPGELSSSPLSQLSSSLSSHQSSLSSTHATRSTSTPHTHASVESTPSSAAFSAATSAPSAPSSGVALPGSMSTVSSLCLGGTTVSAPSSSTRATALVTSGKAPPNLPQGVPPLLHNQYLVGPGGLLPAYPIYGYDELQMLQSRLPMDYYGIPFAAPTALASRDGNLANNPYSGDVTKFGRGDSASPAPPTTPAQAQQSQSQTHHTAQQPFLNPALPPGYSYTGLPYYTGVPGAFQYGPTMFVPPTSAKQHGVTLSTPPTPFQQASGYGQHAYSAGYDDLTQGTAAGDYTKGGYGGSSQAPNKSAGSGPSKGVSVSSGTGLPDMTGSVYNKTQTFDKQGFHTGTPPPFSLPSALGSTGPLAPGAAPGYAPAPFLHIMPAHQQPHSQLLHHHLPQDAPSGSGQRSQPSSLQPKSQASKPTYGNSPYWTN", "length": 1135 }, "evidence": [ { "id": "HGNC:14185", "url": "https://alliancegenome.org/gene/HGNC:14185#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-16#orthology", "database": "AGR" }, { "id": "MGI:1916176", "url": "https://alliancegenome.org/gene/MGI:1916176#orthology", "database": "AGR" }, { "id": "RGD:1311717", "url": "https://alliancegenome.org/gene/RGD:1311717#orthology", "database": "AGR" }, { "id": "FB:FBgn0020279", "url": "https://alliancegenome.org/gene/FB:FBgn0020279#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZUK2-1", "protein_name": "Ubiquitin associated protein 2-like", "gene_name": "Ubap2l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMTSVGTNRARGNWEQPQNQNQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDGGQTESNEEGKENRDRDRDYSRRRGGPPRRGRGASRGRECMHGALSKPAVVRGQENGLDGTKSGGPSGRGTDRGRRGRGRGRGSSGRRGGRFSAQGMGTFNPADYAEPANTDDNYGSSSGNTWNNTGHFEPDDGTRLDFIGVEGSNYPRKFETAPGMIHPGAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTPSSMENDSSNLDPSQAPSLAQPLVFSNSKQNAISQPASGNTFSHHSMVSMLGKGFGDVGEAKGGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLKSANDSTVHSPFTKRQAFTPSSTMMEVFLQEKPPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQKLKQQKKKTSLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLSDYESTPTTSASSSQAPSSLYTSTASESSSTVSSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSESPSTSSIPSLNETVPAASLLTTASQHSSSLSGLSHSEEIPNTTTTQHSSALSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQQNQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHSGTPAASFNLPSALGSGGPINPATAAAYPPAPFMHILTPHQQPHSQILHHHLQQDGQTGSGQRSQTSSIPQKPQTNKSAYNSYSWGAN", "length": 1123 }, "evidence": [ { "id": "FB:FBgn0020279", "url": "https://alliancegenome.org/gene/FB:FBgn0020279#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M2B5X1-1", "protein_name": "Ubiquitin-associated protein 2-like isoform X1", "gene_name": "ubap2l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMTSVGGSRARGNWEQTQGQTQSQSQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLVDITGKDQDESMIALHDCNGDVNRAINVLLEGSPDTDSWEMVGKKKVSGQKESAQTDGGDEGKENRERGGERDVARRRGGAPRRGRGASRGREFRGQENGLDGAKAGGVAGRGTERGRRGRGRGRAGGAGRRGGRFSAQGMGQIDKGPRYDFSGDESTFNPADYTEPAQTEESYTSGSTWSNTGNLEPEDGNRLEFTGGEGTNYPLKFDSAPGAWRTATEEWGTEDWNEDLSETKIFTASSVASMPIPQENVTITAGQRIDLAVLLGKTPPSSSEAEPASLEGPQPQSLSQSLVFSNSKQTSSLSQSSSSAPYSQHNMVSMLGKGFGDVGDPKTTTGGSTTGSQFLEQFKTAQALAQLAAQHSQSGPPNAGPSTWDTSPSALGQYDMKPQTEPVHSPFTKRQPYQPASTTTSMMDAFLQDKTTGPSSTSALPPQSTQASSLAQAITTPVSKPMGAAPGQQNSSSPADPQASSPLPLQQHKLKQQKKRASITTKIPALAVEMPGSADISGLNLQFGALQFGSEPVLPEYDASAAVATTTPGNQGQNSLYTSASNEQATALSNPSQMELYESRANQTRRYPPSVSSSPQKDMQTKNGFSSIQTSQSLEAAAGSAVPVKPVSESVVPPSVSNMVSLADPSSGPTSLLTTSNQTPLSALSHEDVSPSSLATQHNNSLSTQQNSLAPSSVRTSNTSLLHPVDGDSSLHSSSFSVSAVAPSSVPPPSSITSVAPVSHSGPVVPPSSVSLVSTQSSMGPVSLAMGLNNAVVSMVPPSAAASSSSSAASASAAPSSASLSRSTAASGKAPPNLPPGVPPLLPNPYIMAPGLLHPYPPQVYGYDDLQMLQTRIPLDYYSIPFATPTTALTGREGGLTSNPYSAGDLSKFGRNDASSPAPATTLAQPQQTQTQTHHTTQQPFLNPALPPGYSYTSLPYYTGVPGLPNTFQYGPAMFPVAPTSSKQHGVNVGVNASATAFQQASGYGSHGYSTGYEDLGQASAGSGDFCKGGYSTAVAAAAAAAAAAAAASAQNKPASSVTGPGVGVSVTSSNTGVPDISGSVYTKTQSFEKQGFHTGTPSASFSLPSALGSAGPINPPAAAGYAPAPYMHILTPHQQPHSQMLHHHLQQDGQSGSGQRSQNASIQQKSQINKSGYNSYNWGGN", "length": 1212 }, "evidence": [ { "id": "FB:FBgn0020279", "url": "https://alliancegenome.org/gene/FB:FBgn0020279#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BEK9-1", "protein_name": "Ubiquitin-associated protein 2b isoform X1", "gene_name": "ubap2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMTSVVTDAARGNRDRAPPQTTHTSQPQKQIQATAEQIRLAKMIDKKDADFEKKVQQLMEVTGKNQDECMVSLHDCNGDVNRAINFLLEEVTVKDSWETVGKKKSVGKEGIAPEGREKKSEREGRGRGGPNRRGRGASRNQEGRSEENGFESAQVERGGERGRRGRGRGVGGRGRGRGAGISRSSQGIGRTFNPADYTSSAEAGNETTEGAGAWKDNLEDWAAEDWNEDLSETKVFTASYALSSKNHMEPGQGLDLSSLLPKVTEGNSELLGMEPSCPDTLTQSLVFTNSQQHNSRAHTHSYASAAAGTYAHAASSMVGSRLPQSDVQRIEPIITPRITPLSNQVSVPLSSGSASVESTASLPLESTPTVIEPKETPVTTAHLDLKAQPDPSPILSHLSQHQNAALQSDLPTQARDPAPLPPHDGTTHTLKPLCEPVFTMAELSQPRNIRPQKRRVPPPSKIPSSAVEMPGSADVSGLNVKFGALDFESESAVENLNQSESHHQEPVAEAPTQCSLYTKPTAISESLGSLPPAAMEPSYPSASLGLPSTSVPPALSPSSTSRVESSSTTPLSNGFTEMRTSSTQEAVPSSTPQTVSAVLPTENGLPSSSLTSSSSSAPPALSAPLPSLSSHVSSVNSPAASGPTSSSLNIGTDVNVSLSTYSGSVSSVSSSAVISNGLSTGTQSITTNGPSAPSAVRSAPPQTNITPSNNTGKAPPNLAQGVPPLLPSQYIMGPGGLLPAYPPIYGYEDLQMMQSRLPMDYYGMFPGTALAGRDGGLASNPYSGEPTKFGRSDSNSPAPATSLSTVPPSQTQQNAVPPQNQGPQNPGQAQQGQTQAFLNPPLPPGYGYTSLPYYPGMPGMPSAFQYGPTVFMPQTSTKQHNMGPSSQYQHQAGYSQHTYGPGFDELSQAHAGGEYGKVGYGGNSLSQSKVVNNNTGKAPGLSGSTSSELTGTVYSKNQTFEKQGFPTAAGPAFSLPSALGGTGPLNPAGAPGYAPAPFLHILPHQQAPSQLLHHHMGQDTQGQRSQSNSMQKSQSKSNYSSSPYWTN", "length": 1047 }, "evidence": [ { "id": "HGNC:14185", "url": "https://alliancegenome.org/gene/HGNC:14185#orthology", "database": "AGR" }, { "id": "MGI:1916176", "url": "https://alliancegenome.org/gene/MGI:1916176#orthology", "database": "AGR" }, { "id": "RGD:1311717", "url": "https://alliancegenome.org/gene/RGD:1311717#orthology", "database": "AGR" }, { "id": "FB:FBgn0020279", "url": "https://alliancegenome.org/gene/FB:FBgn0020279#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q14157-2", "protein_name": "Ubiquitin-associated protein 2-like", "gene_name": "UBAP2L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMTSVGTNRARGNWEQPQNQNQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDGGQTESNEEGKENRDRDRDYSRRRGGPPRRGRGASRGREFRGQENGLDGTKSGGPSGRGTERGRRGRGRGRGGSGRRGGRFSAQGMGTFNPADYAEPANTDDNYGNSSGNTWNNTGHFEPDDGTSAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTPSTMENDSSNLDPSQAPSLAQPLVFSNSKQTAISQPASGNTFSHHSMVSMLGKGFGDVGEAKGGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLKNPSDSAVHSPFTKRQAFTPSSTMMEVFLQEKSPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQKLKQQKKKASLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLSDYESTPTTSASSSQAPSSLYTSTASESSSTISSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSDSPSTSSIPPLNETVSAASLLTTTNQHSSSLGGLSHSEEIPNTTTTQHSSTLSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQQNQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHSGTPAASFNLPSALGSGGPINPATAAAYPPAPFMHILTPHQQPHSQILHHHLQQDGQTGSGQRSQTSSIPQKPQTNKSAYNSYSWGAN", "length": 1087 }, "evidence": [ { "id": "FB:FBgn0020279", "url": "https://alliancegenome.org/gene/FB:FBgn0020279#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5T6F2-1", "protein_name": "Ubiquitin-associated protein 2", "gene_name": "UBAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMTSVSSDHCRGAREKPQISAAQSTQPQKQVVQATAEQMRLAQVIFDKNDSDFEAKVKQLMEVTGKNQDECIVALHDCNGDVNKAINILLEGNSDTTSWETVGCKKKNFAKENSENKENREKKSEKESSRGRGNNNRKGRGGNRGREFRGEENGIDCNQVDKPSDRGKRARGRGFGRGRGRGAGRFSTQGMGTFNPADYSDSTSTDVCGTKLVVWEAAQNGADEGTELASNTHNIAQDLSNKSSYGLKGAWKNSVEEWTTEDWTEDLSETKVFTASSAPAENHILPGQSIDLVALLQKPVPHSQASEANSFETSQQQGFGQALVFTNSQHNNQMAPGTGSSTAVNSCSPQSLSSVLGSGFGELAPPKMANITSSQILDQLKAPSLGQFTTTPSTQQNSTSHPTTTTSWDLKPPTSQSSVLSHLDFKSQPEPSPVLSQLSQRQQHQSQAVTVPPPGLESFPSQAKLRESTPGDSPSTVNKLLQLPSTTIENISVSVHQPQPKHIKLAKRRIPPASKIPASAVEMPGSADVTGLNVQFGALEFGSEPSLSEFGSAPSSENSNQIPISLYSKSLSEPLNTSLSMTSAVQNSTYTTSVITSCSLTSSSLNSASPVAMSSSYDQSSVHNRIPYQSPVSSSESAPGTIMNGHGGGRSQQTLDTPKTTGPPSALPSVSSLPSTTSCTALLPSTSQHTGDLTSSPLSQLSSSLSSHQSSLSAHAALSSSTSHTHASVESASSHQSSATFSTAATSVSSSASSGASLSSSMNTANSLCLGGTPASASSSSSRAAPLVTSGKAPPNLPQGVPPLLHNQYLVGPGGLLPAYPIYGYDELQMLQSRLPVDYYGIPFAAPTALASRDGSLANNPYPGDVTKFGRGDSASPAPATTPAQPQQSQSQTHHTAQQPFVNPALPPGYSYTGLPYYTGMPSAFQYGPTMFVPPASAKQHGVNLSTPTPPFQQASGYGQHGYSTGYDDLTQGTAAGDYSKGGYAGSSQAPNKSAGSGPGKGVSVSSSTTGLPDMTGSVYNKTQTFDKQGFHAGTPPPFSLPSVLGSTGPLASGAAPGYAPPPFLHILPAHQQPHSQLLHHHLPQDAQSGSGQRSQPSSLQPKSQASKPAYGNSPYWTN", "length": 1119 }, "evidence": [ { "id": "HGNC:14185", "url": "https://alliancegenome.org/gene/HGNC:14185#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-16#orthology", "database": "AGR" }, { "id": "MGI:1916176", "url": "https://alliancegenome.org/gene/MGI:1916176#orthology", "database": "AGR" }, { "id": "RGD:1311717", "url": "https://alliancegenome.org/gene/RGD:1311717#orthology", "database": "AGR" }, { "id": "FB:FBgn0020279", "url": "https://alliancegenome.org/gene/FB:FBgn0020279#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80X50-1", "protein_name": "Ubiquitin-associated protein 2-like", "gene_name": "Ubap2l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMTSVGTNRARGNWEQPQNQNQTQHKQRPQATAEQIRLAQMISDHNDADFEEKVKQLIDITGKNQDECVIALHDCNGDVNRAINVLLEGNPDTHSWEMVGKKKGVSGQKDGGQTESNEEGKENRDRDRDYSRRRGGPPRRGRGASRGREFRGQENGLDGTKSGGPSGRGTDRGRRGRGRGRGSSGRRGGRFSAQGMGTFNPADYAEPANTDDNYGNSSGNTWNNTGHFEPDDGTRLDFIGVEGSNYPRKFETAPGAWRTATEEWGTEDWNEDLSETKIFTASNVSSVPLPAENVTITAGQRIDLAVLLGKTPSSMENDSSNLDPSQAPSLAQPLVFSNSKQNAISQPASGSTFSHHSMVSMLGKGFGDVGEAKGGSTTGSQFLEQFKTAQALAQLAAQHSQSGSTTTSSWDMGSTTQSPSLVQYDLKSANDSTVHSPFTKRQAFTPSSTMMEVFLQEKPPAVATSTAAPPPPSSPLPSKSTSAPQMSPGSSDNQSSSPQPAQQKLKQQKKKTSLTSKIPALAVEMPGSADISGLNLQFGALQFGSEPVLSDYESTPTTSASSSQAPSSLYTSTASESSSTVSSNQSQESGYQSGPIQSTTYTSQNNAQGPLYEQRSTQTRRYPSSISSSPQKDLTQAKNGFSSVQATQLQTTQSVEGATGSAVKSESPSTSSIPSLNETVPAASLLTTANQHSSSLSGLSHTEEIPNTTTTQHSSALSTQQNTLSSSTSSGRTSTSTLLHTSVESEANLHSSSSTFSTTSSTVSAPPPVVSVSSSLNSGSSLGLSLGSNSTVTASTRSSVATTSGKAPPNLPPGVPPLLPNPYIMAPGLLHAYPPQVYGYDDLQMLQTRFPLDYYSIPFPTPTTPLTGRDGSLASNPYSGDLTKFGRGDASSPAPATTLAQPQQNQTQTHHTTQQTFLNPALPPGYSYTSLPYYTGVPGLPSTFQYGPAVFPVAPTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTSSNTGVPDISGSVYSKTQQSFEKQGFHSGTPAASFNLPSALGSGGPINPATAAAYPPAPFMHILTPHQQPHSQILHHHLQQDGQTGSGQRSQTSSIPQKPQTNKSAYNSYSWGAN", "length": 1107 }, "evidence": [ { "id": "FB:FBgn0020279", "url": "https://alliancegenome.org/gene/FB:FBgn0020279#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86S05-1", "protein_name": "Protein lingerer", "gene_name": "lig", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTQTRSGGGGGGGHARNQKKSNASNSGGGGTGHHDGVSHAAAAGKKGGQDASKTDKPEKAQPKATTEQLRIAQITNSTTEDPQINEKVLLLLTMTQRSEEEVCCALNECDYDLEAAANFLIEELPQGAFAKYEKKRKNKAANNTADGAAGDGDWADGNGNADRREKSRNRSSNRGGTRGSSDSRGWRGRETRENERNQRESREPWSGQNAGQDRGDDRANDNYRGQRNGGGRSGPGGGGRGGGFVSRSGRGGGRMGGRTGGPRGDRGSGGPGGAYGSGRGGNANEDHHEVELWDNTIAQNAEKQQQAHDDAWGDWNNEEYEGSLKDSKVFTTSNLATQSAANVVSGTGASVTAVPAAAGTEISAPPGLEHQLVQQGSHLEESSSSGPAAVTPPATLSGSATTPLLQYSAAVSNPPPQLQSQGTQSGAGTGASAAAGGGAGSTPSSFVSASPDTFSSAASAAATLVHQAQKQQQLQQQTTPIKPSATLSVEQSQYFNSLASQGVSPGSVPVQSAPAGYAQNPVAAYSQTSTSVGVSQYPNTYANVFASGTAAGAGTAEQSQQQPQIRRARVKLPPPSKIPASAVEMPGDNALNNIGYLDVQFGALDFGTDDGFEPLPEKVGSGFSIDGQQQQQQPDDYQSKSQQQQQVTLAAGLQSSQISDALNAAGYTSRSTSQQQQGVSSAVNATIDQLTKSDPYGQTGGSGNAYQNAYQSSGASKTASGFPTTAPGGYSSSTYANVQSSVANSYQQQGYGSYQPSSYQQQAGSGAQSGTGAVSGGGGTATQNIPVGGSSSQNSTSGNASSAYLTSGYSTPQSAYQSSQSVYGNTGLSNSSGFSGSASNASSQYANFSASAKLKDATTASSAAHYDSVSTSSGVSSNSGSTGNGGVVSGQTGANQAAVSNNNSVSGSSSVSNVTAGVASGNVAGVGGGVSQSGVSSGVGVPGGSASSVGVNVNNNSSSASSVGAATVAQTATGTTAAVLASLTNKNTSSSNSSGSGGSAATTTGNASGQGAGASTGGVGSSSGAGGAGSGGGSGSGLVPTNIQMVSQYIQTGLPYYQQPVYSYEELQMMQQRVPHVQGYYDLNYPPASLGAGRDNLGSVTYSAMNDGRFARTDNNSSPVGNVSSTMSQQAGSSAPMLNVPYAYFYGGNVMPGSFQYGTPAIYPQIPAANTASGQQFPKPSYSAGYGSTSYDTLSQTTQDYSKGGYSSSVNQQSKTQTVSNQSQAGTGSDLTSSMYGKGHVALNKVNSYEKQSFHSGTPPPFNMPNTQTAGGTSAQPYGMYLPMPAAGHHNMIHQPIHQVHSELPLQVVVGGGTESHVLIHGNVNGPQVTYHRIWQTEPVQCQNQLVAAHCNNFEPNIDCCVHDNNNDLSFFAD", "length": 1375 }, "evidence": [ { "id": "HGNC:14185", "url": "https://alliancegenome.org/gene/HGNC:14185#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-16#orthology", "database": "AGR" }, { "id": "MGI:1916176", "url": "https://alliancegenome.org/gene/MGI:1916176#orthology", "database": "AGR" }, { "id": "RGD:1311717", "url": "https://alliancegenome.org/gene/RGD:1311717#orthology", "database": "AGR" }, { "id": "FB:FBgn0020279", "url": "https://alliancegenome.org/gene/FB:FBgn0020279#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q91VX2-1", "protein_name": "Ubiquitin-associated protein 2", "gene_name": "Ubap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMTSVSNDRCRGAREKPQMPTAHAAQSQKQVVQATAEQMRLAQVIFDKNDSDFEAKVKQLMEVTGKNQDECIVALHDCNGDVNKAINILLEGNSDTTSWETVGGKKKNFGRESSENKENREKRTEREASRGRGTNNRKGRGGNRVREFKGEENGIDCSQGDKPAERGKRARGRGFGRGRGRGTGRFSAQSMGTFNPADYSESMSTDGCGTKLAVWEAAQNGTDEGPEGLAKSHSMSQEPPSKSSYGLKGAWKNSVEEWTTEDWTEDLSETKVFTASSAPAENHVTPGHSIDLVALLHKPAPPTQATEVNSFETSQQQGFGQALVFTNSQHNNQMAPGTANSTSASSYSPQSLSSVLGSGFGELPQSNMVNISNSQILDKLKPPGLSPFPAASSAQQNDTASPPATTAAWDLKPSAPQPSVLSRLDFKSQPEPSPVLSQLSQRQQHQTQAVSVPPPGLESFSSLAKPRESTAGDGPSTVSRLLQLPNMTVENIVSAHQPQPKHIKLPKRRVPPASKVPVSAVEMPGSSDVTGLNVQFGALEFGSEPSLSEFGSAASASENSNQIPISLYPKSLSEPLNASFPMTSAVQSSTYTTSVVTSSTLTSSALSSTSPVTTSSSYDQSSVHTRIAYQSSASPPDSAPGSVANGHGGGRSQHTVDTTSSVPAPKKTDPSALPSVSTLPGPASCTALLPSSAQHTATLPSLTPAAAELSSSPLSQLSSSLSGHQNSMTSAHATRSTSTPHTHASVESTASSAAFSAAATSAPSAPSSGVVLPGSMSTVSSLCLGGTTVSVPSSSTRATALVTSGKAPPNLPQGVPPLLHNQYLVGPGGLLPAYPIYGYDELQMLQSRLPMDYYGIPFAAPTALASRDGNLANNPYSGDVTKFGRGDSASPAPPTTPAQAQQSQSQTHHTAQQPFLNPGLPPGYSYTGLPYYTGVPSAFQYGPTMFVPPTSAKQHGVALSTPPTPFQQASGYGQHAYSTGYDDLTQGTAAGDYTKGGYGGSSQAPNKSTGSGPGKGVSVSSGTGLPDMTGSVYNKTQTFDKQGFHAGTPPPFSLPSALGSTGPLAPAAAPGYAPAPFLHIMPAHQQPHSQLLHHHLQQDAPSGSGQRSQPSSLQPKSQASKPTYGSAPYWTN", "length": 1132 }, "evidence": [ { "id": "HGNC:14185", "url": "https://alliancegenome.org/gene/HGNC:14185#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-16#orthology", "database": "AGR" }, { "id": "MGI:1916176", "url": "https://alliancegenome.org/gene/MGI:1916176#orthology", "database": "AGR" }, { "id": "RGD:1311717", "url": "https://alliancegenome.org/gene/RGD:1311717#orthology", "database": "AGR" }, { "id": "FB:FBgn0020279", "url": "https://alliancegenome.org/gene/FB:FBgn0020279#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3P0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3P0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3P0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "hematopoietic stem cell homeostasis", "id": "GO:0061484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061484", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3P0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1036, "end_pos": 1038, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1078, "end_pos": 1080, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1164, "end_pos": 1166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 783, "end_pos": 785, "annotation": "n_glycosylation_sequon" }, { "start_pos": 803, "end_pos": 805, "annotation": "n_glycosylation_sequon" }, { "start_pos": 826, "end_pos": 828, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z3P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P0" }, { "id": "SM00165", "database": "SMART", "url": 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{ "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9P4B9-1", "uniprot_ac": "A0A8M9P4B9", "uniprot_id": "A0A8M9P4B9_DANRE", "mass": { "chemical_mass": 51135.0, "monoisotopic_mass": 51135.0 }, "refseq": { "ac": "XP_021325047", "name": "interferon-induced protein 44f5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325047" }, "gene_names": [ { "name": "ifi44f5", "type": "recommended", "evidence": [ { "id": "A0A8M9P4B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9" } ] }, { "name": "si:ch211-197g15.9", "type": "recommended", "evidence": [ { "id": "A0A8M9P4B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9" } ] }, { "name": "ifi44f2", "type": "synonym", "evidence": [ { "id": "XP_021325047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325047" }, { "id": "A0A8M9P4B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9" } ] }, { "name": "ifi44f5", "type": "synonym", "evidence": [ { "id": "XP_021325047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325047" }, { "id": "A0A8M9P4B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9" } ] }, { "name": "ifi44f6", "type": "synonym", "evidence": [ { "id": "XP_021325047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325047" }, { "id": "A0A8M9P4B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9" } ] }, { "name": "si:ch211-197g15.6", "type": "synonym", "evidence": [ { "id": "XP_021325047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325047" }, { "id": "A0A8M9P4B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9" } ] } ], "protein_names": [ { "name": "Interferon-induced protein 44f5 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P4B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9/entry#names_and_taxonomy" } ] }, { "name": "interferon-induced protein 44f5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325047" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325047", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325047" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4B9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ifi44f5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050208-457", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-457", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ZFIN:ZDB-GENE-050208-616", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-616", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P4B9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P4B9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000094747", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000094747", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00882", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00882", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "555440", "url": "https://www.ncbi.nlm.nih.gov/gene/555440", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "571364", "url": "https://www.ncbi.nlm.nih.gov/gene/571364", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:555440", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555440", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "dre:571364", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571364", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EMINGPI", "url": "https://omabrowser.org/oma/group/EMINGPI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "NCTEVES", "url": "https://omabrowser.org/oma/group/NCTEVES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AMC1", "url": "https://www.orthodb.org/?gene=A0A8M3AMC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P4B9", "url": "https://www.orthodb.org/?gene=A0A8M9P4B9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0AC58IFA1", "url": "https://www.orthodb.org/?gene=A0AC58IFA1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q1LVY8", "url": "https://www.orthodb.org/?gene=Q1LVY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14241:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14241:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01926", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01926", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325047", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325047", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3AMC1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AMC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AMC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AMC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P4B9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P4B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IFA1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IFA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IFA1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IFA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q1LVY8", "url": "https://www.uniprot.org/uniprotkb/Q1LVY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q1LVY8-1", "url": "https://www.uniprot.org/uniprotkb/Q1LVY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050208-457", "url": "https://zfin.org/ZDB-GENE-050208-457", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] }, { "id": "ZDB-GENE-050208-616", "url": "https://zfin.org/ZDB-GENE-050208-616", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNPLNSKLTKRQGPQLCDLLGDVDLTLLYKASVHGYEASAFHRRCDNQGPSLLVAYNNSGYIFGGYTSVDYTQSCNAVTDDKAFLFNINGAVPLVIKVNSRHYLRYGGNGGPSFGEQLYFCYNDQPPVYNQGRNAYQVMAFTISPPTMAFTFSPATLYGNNTNLIECEVFKVEQKKDQVNAVIKIKPWRNVQWTAKQRDELMKMIRNYKPLTTSVSQVKILMIGPVRAGKSSFFNSINSIFMGRMTSKAMSGSAGTSLTTQFRTYPIKDGREGKPLPFVLCDTMGLEEQSGAGLDIEDISSILQGQIPDRYKFNPVTPCQPDEQKSTRPASLQDKIHSVVYVIDATKISLMSEKPEEKLSAIRKKINSLAIPQVVLMTKVDEACPDVQENLQSVYASSYIKTKVQEVSSRLGVPVSCVLPVKNYSQELELELNCDVLLLTALQQMLNFAEDYLDDVAPM", "length": 459, "header": "tr|A0A8M9P4B9-1|A0A8M9P4B9_DANRE Isoform 1 of Interferon-induced protein 44f5 isoform X1 OS=Danio rerio OX=7955 GN=ifi44f5 PE=3 SV=1 CANONICAL=A0A8M9P4B9-1" }, "isoforms": [ { "isoform_ac": "A0A8M3AMC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9/entry#A0A8M3AMC1-1", "sequence": { "sequence": "MNKHKVRDVTVNTLTSNLPEDKRKQLCALLGDVDLTLLYKASVHGYNASAFHQRCDRQGPTLLVAYNSSGYIFGGYTSVDFTQSGQYIADEDIFLFCFQGKIPVCMKLNSGYNARLDDTGVPSFGQQLYFCYNNQPMVYNQGVSAFTVNTAIMYGNDTQLSECEVYKVEQSTQVKFEVKPWRSVLWTAERREELMEMIRNYKPLTSSVSHIRILMIGPVGAGKSSFFNSINSIFMGRITSKAMSGSAGTSLTTQFRTYPIKDGREGKPLPFVLCDTMGLEEQSGAGLDIEDISSILQGQIPDRYKFNPVTSFQPDEQKSSRPASLQEKIHCVVYVIDATKISLMSEKLEEKLSAIRRKVNSLGAGGELSVGCAGVLCFTGEELQSGAGAGAEL", "length": 393, "header": "tr|A0A8M3AMC1-1|A0A8M9P4B9_DANRE Computationally mapped isoform of Interferon-induced protein 44f5 isoform X1 OS=Danio rerio OX=7955 GN=ifi44f5 PE=3 SV=1 CANONICAL=A0A8M9P4B9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P4B9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9/entry#A0A8M9P4B9-1", "sequence": { "sequence": "MNPLNSKLTKRQGPQLCDLLGDVDLTLLYKASVHGYEASAFHRRCDNQGPSLLVAYNNSGYIFGGYTSVDYTQSCNAVTDDKAFLFNINGAVPLVIKVNSRHYLRYGGNGGPSFGEQLYFCYNDQPPVYNQGRNAYQVMAFTISPPTMAFTFSPATLYGNNTNLIECEVFKVEQKKDQVNAVIKIKPWRNVQWTAKQRDELMKMIRNYKPLTTSVSQVKILMIGPVRAGKSSFFNSINSIFMGRMTSKAMSGSAGTSLTTQFRTYPIKDGREGKPLPFVLCDTMGLEEQSGAGLDIEDISSILQGQIPDRYKFNPVTPCQPDEQKSTRPASLQDKIHSVVYVIDATKISLMSEKPEEKLSAIRKKINSLAIPQVVLMTKVDEACPDVQENLQSVYASSYIKTKVQEVSSRLGVPVSCVLPVKNYSQELELELNCDVLLLTALQQMLNFAEDYLDDVAPM", "length": 459, "header": "tr|A0A8M9P4B9-1|A0A8M9P4B9_DANRE Isoform 1 of Interferon-induced protein 44f5 isoform X1 OS=Danio rerio OX=7955 GN=ifi44f5 PE=3 SV=1 CANONICAL=A0A8M9P4B9-1" }, "locus": {} }, { "isoform_ac": "A0AC58IFA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9/entry#A0AC58IFA1-1", "sequence": { "sequence": "MNKHKVRDVTVNTLTSNLPEDKRKQLCALLGDVDLTLLYKASVHGYNASAFHQRCDRQGPTLLVAYNSSGYIFGGYTSVDFTQSGQYIADEDIFLFCFQGKIPVCMKLNSGYNARLDDTGVPSFGQQLYFCYNNQPMVYNQGVSAFTVNTAIMYGNDTQLSECEVYKVEQSTQVKFEVKPWRSVLWTAERREELMEMIRNYKPLTSSVSHIRILMIGPVGAGKSSFFNSINSIFMGRITSKAMSGSAGTSLTTQFRTYPIKDGREGKPLPFVLCDTMGLEEQSGAGLDIEDISSILQGQIPDRYKFNPVTSFQPDEQKSSRPASLQEKIHCVVYVIDATKISLMSEKLEEKLSAIRRKVNSLGIAQIVLMTKVDEACPLVDEDLQSLYLSSYIKTKVQEVSSRLGVPVSCVLPVKNYSQELELELNCDVLLLTALQQMLNFAEDYLDDVAPK", "length": 452, "header": "tr|A0AC58IFA1-1|A0AC58IFA1_DANRE Computationally mapped isoform of Interferon-induced protein 44-like isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-197g15.9 PE=3 SV=1 CANONICAL=A0A8M9P4B9-1" }, "locus": {} }, { "isoform_ac": "Q1LVY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9/entry#Q1LVY8-1", "sequence": { "sequence": "MVVMVDPALGSSCIFATMTNHQCIIKGEMHINPATLYGNNTNLIECEVFKVEQNQVNAVIKIKPWRNVQWTAKQRDELMKMIRNYKPLTTSVSQVKILMIGPVRAGKSSFFNSINSIFMGRMTSKAMSGSAGTSLTTQFRTYPIKDGREGKPLPFVLCDTMGLEEQSGAGLDIEDISSILQGQIPDRYKFNPVTPCQPDEQKSTRPASLQDKIHSVVYVIDATKISLMSEKPEEKLSAIRKKINSLAIPQVVLMTKVDEACPDVQENLQSVYASSYIKTKVQEVSSRLGVPVSCVLPVKNYSQELELELNCDVLLLTALQQMLNFAEDYLDDVAPM", "length": 336, "header": "tr|Q1LVY8-1|A0A8M9P4B9_DANRE Computationally mapped isoform of Interferon-induced protein 44f5 isoform X1 OS=Danio rerio OX=7955 GN=ifi44f5 PE=3 SV=1 CANONICAL=A0A8M9P4B9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.", "journal": "J. Immunol.", "date": "2014", "authors": "Briolat Val\u00e9rie, Jouneau Luc, Carvalho Ralph, Palha Nuno, Langevin Christelle, Herbomel Philippe, Schwartz Olivier, Spaink Herman P, Levraud Jean-Pierre, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "Q1LVY8", "url": "https://www.uniprot.org/uniprotkb/Q1LVY8" } ], "reference": [ { "type": "PubMed", "id": "24683187", "url": "https://glygen.org/publication/PubMed/24683187" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "Q1LVY8", "url": "https://www.uniprot.org/uniprotkb/Q1LVY8" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity.", "journal": "J. Immunol.", "date": "2019", "authors": "Levraud Jean-Pierre, Jouneau Luc, Briolat Val\u00e9rie, Laghi Valerio, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "Q1LVY8", "url": "https://www.uniprot.org/uniprotkb/Q1LVY8" } ], "reference": [ { "type": "PubMed", "id": "31732531", "url": "https://glygen.org/publication/PubMed/31732531" } ] } ], "pathway": [ { "id": "dre:555440", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555440", "resource": "KEGG Pathway" }, { "id": "dre:571364", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571364", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZW5-1", "protein_name": "Interferon-induced protein 44", "gene_name": "Ifi44", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKIAYLQFYPSVVAEFKQLAPSNSSPVERQDYLPIMLSSLGYTDHDAQIHSSPEGASFSVCSMEEALKGRTLFDQAWPLRWKLPSVAALGQNLRPDRFQNFKRTVLALPLDSSMAMRTRLTWEQEKYLRNYFGEKKFCLLYKASVQEFAGQNLLYKCQDQGPTMVVVYSEKYVIGVYLQEGFQENKVSTTLFTIQETGLSPCALGPCLPLSLFRYEETSDFFILLDKKTVTISSEIRKVLRLPSLSGDTFIQECEAFRCDELLDERKTRGIVGLCSNLLDALRNYKPYGDLVHQTRILLLGPIGAGKSSFVNSVKSVFKGSITHQASVGCDRNGISDKYRTYSIMSKNDSGPLPFVLCDSLGLSENEGLHTDDICHILKGHTPDRYQFDFRKPITPNHPNYIHDPLLKDRIHCVVFVFDINSFNQLSCELVAKIKQIRRDLIKHGILHLALLTHVDSLTWITKGDLLDIYSCNPVKVKLGVFHRLFGFALSDILVVSNYDSEWQLDPVKNMLILSALKEILYTANGFLEDLPLNK", "length": 535 }, "evidence": [ { "id": "HGNC:16938", "url": "https://alliancegenome.org/gene/HGNC:16938#orthology", "database": "AGR" }, { "id": "MGI:2443016", "url": "https://alliancegenome.org/gene/MGI:2443016#orthology", "database": "AGR" }, { "id": "RGD:1310523", "url": "https://alliancegenome.org/gene/RGD:1310523#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-616", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-616#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-457", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-457#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1PZX7-1", "protein_name": "Interferon-induced protein 44", "gene_name": "ifi44a8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGSDSQPEKPYQPPPPPPNPELDKPWRQFDWGQKEALKKWLENFSPCNPNVKSIKILIAGQAGAGKSSFINSIYCGFQGRISSRALVNSIDGDSRSYTQKLKEFTIKTEKKTLPLVFRDIMGLEYEEFHGSKTEDIIKAVFGHVKDGYKFNEEQSIDYKDQHYTSDPSLSDQCFCVVYIIDGSTVQFTDDRLIKKLQIIRKRIKDKGIPQVVVMTKVDEACPLVKKNLRKVYTSKKIKEKMELCSASIGVPMTNIFPVKNYHDEINTNNDVDVLILKALEQIVQIANDRLDDNESY", "length": 297 }, "evidence": [ { "id": "HGNC:16938", "url": "https://alliancegenome.org/gene/HGNC:16938#orthology", "database": "AGR" }, { "id": "MGI:2443016", "url": "https://alliancegenome.org/gene/MGI:2443016#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RFT6-1", "protein_name": "Interferon-induced protein 44-like isoform X1", "gene_name": "ifi44f3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPIASDLPAEQREQLCGLLGNVDLTLLYKASVHGYEASAFHQRCDNQGATLLVAYNNSGDIFGGYTSVDYTQSGKEIADKEAFLFSFRSGNLLCIKVKSGYNARCDDAGMPNFGQQLYFCYNNQPVVIYQHKDCYRQFIFNPDTLYGNNNQLTECEVYQIKQTLQVSFKEKPWRNILWTAERREELMGFFRSHKPLLSSVNRVRILMLGPVGAGKSSFFNSINSIFMGYVTSKAMSGSAKSSVTTQFRMYPVKDGHERKPLPFVLCDTMGLEEQSGAGLDIKDISSILQGHIPDRYRFNPVTPFQPDEQKSSRPASLLEKIHCVVYVIDATKISLMSEKLEEKLTSVRCLINSLAIPQMVVMTKVDEACPHVQKDLQNVYASSYTKMKVQEVSSRLGVPVSCVLPVKNYSQEIELDLNCDVLLLSALHQMLRLADDYLDDVDSF", "length": 445 }, "evidence": [ { "id": "HGNC:16938", "url": "https://alliancegenome.org/gene/HGNC:16938#orthology", "database": "AGR" }, { "id": "MGI:2443016", "url": "https://alliancegenome.org/gene/MGI:2443016#orthology", "database": "AGR" }, { "id": "HGNC:17817", "url": "https://alliancegenome.org/gene/HGNC:17817#orthology", "database": "AGR" }, { "id": "MGI:95975", "url": "https://alliancegenome.org/gene/MGI:95975#orthology", "database": "AGR" }, { "id": "RGD:1595861", "url": "https://alliancegenome.org/gene/RGD:1595861#orthology", "database": "AGR" }, { "id": "RGD:1310523", "url": "https://alliancegenome.org/gene/RGD:1310523#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AXQ2-1", "protein_name": "Interferon-induced protein 44", "gene_name": "ifi44a7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGSPSKPAETPELDQPWRNFDWGEKDKLKEHLEYFQLKSQSLTHIKILVAGQIGAGKSSFINSVVSAFQGKIISVAQTDASDSAISHSFTQTLKAYRIRRADADLPFEICDIMGLEPHTLLGIQPDDVVKTIHGHVKEGYKFTENPIGHKNESYKETPSLSDQAFCLVYVVDANTIQFSSNDNILIEKLRLIRKRISDEGIPQVVVLTKVDELCPLVKKDLQKVFYSKKIREAVRMCNSKIGVPMNLIFPVKNYHEETQTNDVADVLILNAFQQIVCTANERLSHGFSHCSD", "length": 293 }, "evidence": [ { "id": "HGNC:16938", "url": "https://alliancegenome.org/gene/HGNC:16938#orthology", "database": "AGR" }, { "id": "MGI:2443016", "url": "https://alliancegenome.org/gene/MGI:2443016#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A891-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "ifi44f4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQKAKVRKISTETFTSMLPKERKDQLCDSLGDVDLTLLYKASVHGYKASAFHQRCDHQGPTILVAYNRSGYIFGGYTSVDYTQSGREIKDDEAFLFSFHGGNSSFIKVNSGYNARYDDSGAPNFGHQLYFCYNNQSCVLYKGETSSFNINTSSVYGNDTQLVECEVYKVEQDPQVSVEEKPWRKVLWTAERKAELMGLIRSHKPLISSASRVRILMIGPVGAGKSSFFNSINSIFTGHVTSKAMSGSAGTSLTVQFRTYPINDGREGKPLPFVLCDTMGLEEQSGAGLDIEDISSILQGHIPDRYKFNPAAPFQPDEQKSSRPASLQEKIHCVVYVIDATKISLMSEKLEEKLSAIRRKVNSLGIAQIVLMTKVDEACPLVDEDLENVYLSSYIKTKVQEVSSRLGVPVSCVLPVKNYSQELELELNCDVLLLTALQQMLRFADDYFDDIQQPVEGKPV", "length": 459 }, "evidence": [ { "id": "HGNC:16938", "url": "https://alliancegenome.org/gene/HGNC:16938#orthology", "database": "AGR" }, { "id": "MGI:2443016", "url": "https://alliancegenome.org/gene/MGI:2443016#orthology", "database": "AGR" }, { "id": "HGNC:17817", "url": "https://alliancegenome.org/gene/HGNC:17817#orthology", "database": "AGR" }, { "id": "MGI:95975", "url": "https://alliancegenome.org/gene/MGI:95975#orthology", "database": "AGR" }, { "id": "RGD:1595861", "url": "https://alliancegenome.org/gene/RGD:1595861#orthology", "database": "AGR" }, { "id": "RGD:1310523", "url": "https://alliancegenome.org/gene/RGD:1310523#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0R4J5-1", "protein_name": "Interferon-induced protein 44-like", "gene_name": "Ifi44l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNMLGLRGSYRNTKVTTRLTWIEEKILEKLLGNASLTLLYQSNVHKRCTLEMTKKCSLQGSTMTIVYLEQEVVGVFMLEDFPDKDSKKTSTCAWFSFERNKISSGISALVLNTLVKVNSTSLQMSSISGLTLIVYPSKEGLYLNEAVIKNLELNVKQSQYLECEIFRVDGIKNNPGFIKKMVTARQHRGKFLSTLRAYRPYADLVSEVRILLVGPVGSGKSSFVNSVKSSFQGRLTRQAIVGSDKSSITTQYKVYSIKDEKNKETLPFMLCDSMGLEDEKEAGLCTDDIPHILKGCVPDRYQFNPREPIKLKHFTYAASPPLKDRIHCVAFVLDINSVDTLSDKMVAKLKKIRKDVVDCGVGCVALLTNVSDYDEVLDNNLVNMTENMTSLNQVQNVRNMLNIPVANILMVSNYASERMLEPLKDVLIFAALQQMLRAADDALEDLPLEDTASDDGSFNNSSHIKNEGKLGEVKRREMS", "length": 479 }, "evidence": [ { "id": "HGNC:17817", "url": "https://alliancegenome.org/gene/HGNC:17817#orthology", "database": "AGR" }, { "id": "MGI:95975", "url": "https://alliancegenome.org/gene/MGI:95975#orthology", "database": "AGR" }, { "id": "RGD:1595861", "url": "https://alliancegenome.org/gene/RGD:1595861#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-616", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-616#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-457", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-457#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q53G44-1", "protein_name": "Interferon-induced protein 44-like", "gene_name": "IFI44L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVTTRLTWNDENHLRKLLGNVSLSLLYKSSVHGGSIEDMVERCSRQGCTITMAYIDYNMIVAFMLGNYINLHESSTEPNDSLWFSLQKKNDTTEIETLLLNTAPKIIDEQLVCRLSKTDIFIICRDNKIYLDKMITRNLKLRFYGHRQYLECEVFRVEGIKDNLDDIKRIIKAREHRNRLLADIRDYRPYADLVSEIRILLVGPVGSGKSSFFNSVKSIFHGHVTGQAVVGSDITSITERYRIYSVKDGKNGKSLPFMLCDTMGLDGAEGAGLCMDDIPHILKGCMPDRYQFNSRKPITPEHSTFITSPSLKDRIHCVAYVLDINSIDNLYSKMLAKVKQVHKEVLNCGIAYVALLTKVDDCSEVLQDNFLNMSRSMTSQSRVMNVHKMLGIPISNILMVGNYASDLELDPMKDILILSALRQMLRAADDFLEDLPLEETGAIERALQPCI", "length": 452 }, "evidence": [ { "id": "HGNC:17817", "url": "https://alliancegenome.org/gene/HGNC:17817#orthology", "database": "AGR" }, { "id": "MGI:95975", "url": "https://alliancegenome.org/gene/MGI:95975#orthology", "database": "AGR" }, { "id": "RGD:1595861", "url": "https://alliancegenome.org/gene/RGD:1595861#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-616", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-616#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-457", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-457#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BV66-1", "protein_name": "Interferon-induced protein 44", "gene_name": "Ifi44", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMRTRLTWQQEKCLQNYFGGKRFCLLYKASVQKFSHQNLLCTCENQGPTMIVVYSEKCVIGMYLKEGFQGKDVSITIFALQETGFSLCAKGPDSPYLLFHKRKTNDFSILLDEKAVIVSSAICKMLQLTARNNVIPIQECEAFRCEELLDERKTRGIAVLHSNLLQALRDYKPYGDLVQQTRVLLLGPIGAGKSSFVNSVKSVFKGSITHQILVGCDEDGISDKYRTYSIKAKDDSDPLPFILCDSLGLGENAGLHTDDVWHILKGHTPDRYQFDSMKPITSNHPNYTHDPLLKDRIHCVVFVFDINSFEMHSSELVAKIKKIRRDLIKHGILHLALLTHVDSLDLITKEDMTDIYNYSPVKSKLEAFHGVFGFALSDILVVSNYVSEWQLDPVKDMLILSALKEILYTANEFLEDLPLNK", "length": 422 }, "evidence": [ { "id": "HGNC:16938", "url": "https://alliancegenome.org/gene/HGNC:16938#orthology", "database": "AGR" }, { "id": "MGI:2443016", "url": "https://alliancegenome.org/gene/MGI:2443016#orthology", "database": "AGR" }, { "id": "RGD:1310523", "url": "https://alliancegenome.org/gene/RGD:1310523#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-616", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-616#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-457", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-457#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TCB0-1", "protein_name": "Interferon-induced protein 44", "gene_name": "IFI44", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVTTRLTWLHEKILQNHFGGKRLSLLYKGSVHGFRNGVLLDRCCNQGPTLTVIYSEDHIIGAYAEESYQEGKYASIILFALQDTKISEWKLGLCTPETLFCCDVTKYNSPTNFQIDGRNRKVIMDLKTMENLGLAQNCTISIQDYEVFRCEDSLDERKIKGVIELRKSLLSALRTYEPYGSLVQQIRILLLGPIGAGKSSFFNSVRSVFQGHVTHQALVGTNTTGISEKYRTYSIRDGKDGKYLPFILCDSLGLSEKEGGLCRDDIFYILNGNIRDRYQFNPMESIKLNHHDYIDSPSLKDRIHCVAFVFDASSIQYFSSQMIVKIKRIRRELVNAGVVHVALLTHVDSMDLITKGDLIEIERCEPVRSKLEEVQRKLGFALSDISVVSNYSSEWELDPVKDVLILSALRRMLWAADDFLEDLPFEQIGNLREEIINCAQGKK", "length": 444 }, "evidence": [ { "id": "HGNC:16938", "url": "https://alliancegenome.org/gene/HGNC:16938#orthology", "database": "AGR" }, { "id": "MGI:2443016", "url": "https://alliancegenome.org/gene/MGI:2443016#orthology", "database": "AGR" }, { "id": "RGD:1310523", "url": "https://alliancegenome.org/gene/RGD:1310523#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-616", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-616#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-457", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-457#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9BDB7-1", "protein_name": "Interferon-induced protein 44-like", "gene_name": "Ifi44l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKVTARLTWIEEKILEKLLGNASLTLLYQSSAHKNCVSEMTQKYSLQGSTMTVFHLEKDVVVGVFILENFPRLVSEKPCTCAWFSLKRNNSSGISALFLNTKVIVDSEELIIFSLDGLSLSVTPLRGFTLALNDTVMNGLELNLGHGFLPVECEIFRVDGIKKNPSFIKKMVTAEQHRGKLLSALRAYKPYKDLVSEVRILLVGPVGSGKSSFFNSVKSAFQGHLTRQAIVGSDESSITKQYRVYSIKDGKSGETLPFMLCDSMGLEEGEEAGLCIDDIPHILQGCVPDRYQFNPCEPMKPKHSPHAASPPLKDRIHCVAFVLHINSVNTLSDKMVAKLKKIRKDVVDCGIGYVALLTNVEEYDEVLDDSFANMTETVTSLSQVQNVQKWLNIPIANILMVSNYASERRLEPMKDILVFAALRQMLRAADDALEDLPLEDTGNLAPF", "length": 447 }, "evidence": [ { "id": "HGNC:17817", "url": "https://alliancegenome.org/gene/HGNC:17817#orthology", "database": "AGR" }, { "id": "MGI:95975", "url": "https://alliancegenome.org/gene/MGI:95975#orthology", "database": "AGR" }, { "id": "RGD:1595861", "url": "https://alliancegenome.org/gene/RGD:1595861#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-616", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-616#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-457", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-457#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4B9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4B9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P4B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4B9" }, { "id": "PS51886", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51886" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TLDc", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 173, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M6Z4S8-1", "uniprot_ac": "A0A8M6Z4S8", "uniprot_id": "A0A8M6Z4S8_DANRE", "mass": { "chemical_mass": 102754.0, "monoisotopic_mass": 102754.0 }, "refseq": { "ac": "XP_017209418", "name": "polyhomeotic-like protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209418" }, "gene_names": [ { "name": "phc3b", "type": "recommended", "evidence": [ { "id": "A0A8M6Z4S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8" } ] }, { "name": "si:ch211-230g15.5", "type": "recommended", "evidence": [ { "id": "A0A8M6Z4S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8" } ] }, { "name": "si:ch211-230g15.5", "type": "synonym", "evidence": [ { "id": "XP_017209418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209418" }, { "id": "A0A8M6Z4S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8" } ] } ], "protein_names": [ { "name": "Polyhomeotic-like protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z4S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8/entry#names_and_taxonomy" } ] }, { "name": "polyhomeotic-like protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017209418", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209418" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017209418.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017209418", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209418" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4S8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "phc3b", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-280", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-280", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z4S8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z4S8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000079167", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000079167", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09577", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09577", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "556561", "url": "https://www.ncbi.nlm.nih.gov/gene/556561", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556561", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556561", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HPIFLLC", "url": "https://omabrowser.org/oma/group/HPIFLLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3ANM7", "url": "https://www.orthodb.org/?gene=A0A8M3ANM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z4S8", "url": "https://www.orthodb.org/?gene=A0A8M6Z4S8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12247:SF88", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12247:SF88", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21319", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21319", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017209418", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209418", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3ANM7", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ANM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3ANM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ANM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4S8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PUI1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PUI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PUI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PUI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRS2", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRS2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-280", "url": "https://zfin.org/ZDB-GENE-091204-280", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLLPPTVGKLLVSRFCGTMDKEPQTKAEPAKSTVNTTSTTTVNPSHQANGTPKTPPALTTVTTFHNQPSPTNRKVVQINLSGDRLAPSFSPSERVSQASSSQQTPKTISLPNTPGSTALVRGGQSAVTAVRKISPQTLLLGKSPSTSQAQMLLRAQMLILTSAVRPDVPALSSSFSSSSSFSSSSSSSSSTPSSSSPRFPSTQLQSLTIRPPPPGTLTIPPNLPLKPTTSSQPPPLSCPRIPTFHLRPSQPANAPGKDGATKSESPTSQTAQTKTPVRHLTVPPPSLYAPAQAHALAKQKLNSSSLKRPHSQISIPQHPFNQRHTPPNSPPATPKKPLPELKRCPSTQASQSISPQSASVSITVPSPARAHLTPPTLTLPLRSSSPGGSLLATKQLLRIALSSASAQCTNGQSKTATVSPPHDLIQSKPLLSPVLAKPECPTQPLLTPNTCPQLVQLSPSRQTTAATPLITTPPLASPQRASPPSPVLPLVSTSSILAPPQSPLTSQSPTQTTETSKEPKDRKEEQKQGTVPEQTPQDLKCPAPQKKMTQAVDQLPSEASEKVLNKIIVCTENSRTDGQIKTSQKNETHSPSVAPWPAEKDDQCEETSTQSDNHSAISSLSSDMSPIQSSIAQPLDMSPVDSCFPPKFHPVLERPLVQSSTLSQMKDTEGQQASGAPKPLVLTHLVEGFIIQEGLEPFPVSRSSLMVGPVQDSGVNGVKEPGLIPSGSEHPEDSTDSDDEDGVANSNGVGRAHKLVLQCQFCKRKGTAQTFPRSKRFCSKSCAKRFSYTKRFRALRRCVSEGGHRSELNGAEDSFHQAKHGATEQWRILQQPPQEGEDGTSAPMKTRLRRHTEQEREREIRVRHTVEETRSAPTSPIDPVSPTDITPYPKPAQWTVDQVSSFISKLPGCQDIAESFRAQEIDGQALLLLTEDHLMSAMNVKLGPALKICARINSLREGGR", "length": 960, "header": "tr|A0A8M6Z4S8-1|A0A8M6Z4S8_DANRE Isoform 1 of Polyhomeotic-like protein 3 isoform X1 OS=Danio rerio OX=7955 GN=phc3b PE=4 SV=2 CANONICAL=A0A8M6Z4S8-1" }, "isoforms": [ { "isoform_ac": "A0A8M3ANM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8/entry#A0A8M3ANM7-1", "sequence": { "sequence": "MDKEPQTKAEPAKSTVNTTSTTTVNPSHQANGTPKTPPALTTVTTFHNQPSPTNRKVVQINLSGDRLAPSFSPSERVSQASSSQQTPKTISLPNTPGSTALVRGGQSAVTAVRKISPQTLLLGKSPSTSQAQMLLRAQMLILTSAVRPDVPALSSSFSSSSSFSSSSSSSSSTPSSSSPRFPSTQLQSLTIRPPPPGTLTIPPNLPLKPTTSSQPPPLSCPRIPTFHLRPSQPANAPGKDGATKSESPTSQTAQTKTPVRHLTVPPPSLYAPAQAHALAKQKLNSSSLKRPHSQISIPQHPFNQRHTPPNSPPATPKKPLPELKRCPSTQASQSISPQSASVSITVPSPARAHLTPPTLTLPLRSSSPGGSLLATKQLLRIALSSASAQCTNGQSKTATVSPPHDLIQSKPLLSPVLAKPECPTQPLLTPNTCPQLVQLSPSRQTTAATPLITTPPLASPQRASPPSPVLPLVSTSSILAPPQSPLTSQSPTQTTETSKEPKDRKEEQKQGTVPEQTPQDLKCPAPQKKMTQAVDQLPSEASEKVLNKIIVCTENSRTDGQIKTSQKNETHSPSVAPWPAEKDDQCEETSTQSDNHSAISSLSSDMSPIQSSIAQPLDMSPVDSCFPPKFHPVLERPLVQSSTLSQMKDTEGQQASGAPKPLVLTHLVEGFIIQEGLEPFPVSRSSLMVGPVQDSGVNGVKEPGLIPSGSEHPEDSTDSDDEDGVANSNGVGRAHKLVLQCQFCKRKGTAQTFPRSKRFCSKSCAKRFSYTKRFRALRRCVSEGGHRSELNGAEDSFHQAKHGATEQWRILQQPPQEGEDGTSAPMKTRLRRHTEQEREREIRVRHTVEETRSAPTSPIDPVSPTDITPYPKPAQWTVDQVSSFISKLPGCQDIAESFRAQEIDGQALLLLTEDHLMSAMNVKLGPALKICARINSLREGGR", "length": 942, "header": "tr|A0A8M3ANM7-1|A0A8M6Z4S8_DANRE Computationally mapped isoform of Polyhomeotic-like protein 3 isoform X1 OS=Danio rerio OX=7955 GN=phc3b PE=4 SV=2 CANONICAL=A0A8M6Z4S8-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z4S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8/entry#A0A8M6Z4S8-1", "sequence": { "sequence": "MLLPPTVGKLLVSRFCGTMDKEPQTKAEPAKSTVNTTSTTTVNPSHQANGTPKTPPALTTVTTFHNQPSPTNRKVVQINLSGDRLAPSFSPSERVSQASSSQQTPKTISLPNTPGSTALVRGGQSAVTAVRKISPQTLLLGKSPSTSQAQMLLRAQMLILTSAVRPDVPALSSSFSSSSSFSSSSSSSSSTPSSSSPRFPSTQLQSLTIRPPPPGTLTIPPNLPLKPTTSSQPPPLSCPRIPTFHLRPSQPANAPGKDGATKSESPTSQTAQTKTPVRHLTVPPPSLYAPAQAHALAKQKLNSSSLKRPHSQISIPQHPFNQRHTPPNSPPATPKKPLPELKRCPSTQASQSISPQSASVSITVPSPARAHLTPPTLTLPLRSSSPGGSLLATKQLLRIALSSASAQCTNGQSKTATVSPPHDLIQSKPLLSPVLAKPECPTQPLLTPNTCPQLVQLSPSRQTTAATPLITTPPLASPQRASPPSPVLPLVSTSSILAPPQSPLTSQSPTQTTETSKEPKDRKEEQKQGTVPEQTPQDLKCPAPQKKMTQAVDQLPSEASEKVLNKIIVCTENSRTDGQIKTSQKNETHSPSVAPWPAEKDDQCEETSTQSDNHSAISSLSSDMSPIQSSIAQPLDMSPVDSCFPPKFHPVLERPLVQSSTLSQMKDTEGQQASGAPKPLVLTHLVEGFIIQEGLEPFPVSRSSLMVGPVQDSGVNGVKEPGLIPSGSEHPEDSTDSDDEDGVANSNGVGRAHKLVLQCQFCKRKGTAQTFPRSKRFCSKSCAKRFSYTKRFRALRRCVSEGGHRSELNGAEDSFHQAKHGATEQWRILQQPPQEGEDGTSAPMKTRLRRHTEQEREREIRVRHTVEETRSAPTSPIDPVSPTDITPYPKPAQWTVDQVSSFISKLPGCQDIAESFRAQEIDGQALLLLTEDHLMSAMNVKLGPALKICARINSLREGGR", "length": 960, "header": "tr|A0A8M6Z4S8-1|A0A8M6Z4S8_DANRE Isoform 1 of Polyhomeotic-like protein 3 isoform X1 OS=Danio rerio OX=7955 GN=phc3b PE=4 SV=2 CANONICAL=A0A8M6Z4S8-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PUI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8/entry#A0A8M9PUI1-1", "sequence": { "sequence": "MLLPPTVGKLLVSRFCGTMDKEPQTKAEPAKSTVNTTSTTTVNPSHQANGTPKTPPALTTVTTFHNQPSPTNRKVVQINLSGDRLAPSFSPSERVSQASSSQQTPKTISLPNTPGSTALVRGGQSAVTAVRKISPQTLLLGKSPSTSQAQMLLRAQMLQSLTIRPPPPGTLTIPPNLPLKPTTSSQPPPLSCPRIPTFHLRPSQPANAPGKDGATKSESPTSQTAQTKTPVRHLTVPPPSLYAPAQAHALAKQKLNSSSLKRPHSQISIPQHPFNQRHTPPNSPPATPKKPLPELKRCPSTQASQSISPQSASVSITVPSPARAHLTPPTLTLPLRSSSPGGSLLATKQLLRIALSSASAQCTNGQSKTATVSPPHDLIQSKPLLSPVLAKPECPTQPLLTPNTCPQLVQLSPSRQTTAATPLITTPPLASPQRASPPSPVLPLVSTSSILAPPQSPLTSQSPTQTTETSKEPKDRKEEQKQGTVPEQTPQDLKCPAPQKKMTQAVDQLPSEASEKVLNKIIVCTENSRTDGQIKTSQKNETHSPSVAPWPAEKDDQCEETSTQSDNHSAISSLSSDMSPIQSSIAQPLDMSPVDSCFPPKFHPVLERPLVQSSTLSQMKDTEGQQASGAPKPLVLTHLVEGFIIQEGLEPFPVSRSSLMVGPVQDSGVNGVKEPGLIPSGSEHPEDSTDSDDEDGVANSNGVGRAHKLVLQCQFCKRKGTAQTFPRSKRFCSKSCAKRFSYTKRFRALRRCVSEGGHRSELNGAEDSFHQAKHGATEQWRILQQPPQEGEDGTSAPMKTRLRRHTEQEREREIRVRHTVEETRSAPTSPIDPVSPTDITPYPKPAQWTVDQVSSFISKLPGCQDIAESFRAQEIDGQALLLLTEDHLMSAMNVKLGPALKICARINSLREGGR", "length": 914, "header": "tr|A0A8M9PUI1-1|A0A8M6Z4S8_DANRE Computationally mapped isoform of Polyhomeotic-like protein 3 isoform X1 OS=Danio rerio OX=7955 GN=phc3b PE=4 SV=2 CANONICAL=A0A8M6Z4S8-1" }, "locus": {} }, { "isoform_ac": "A0AC58IRS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8/entry#A0AC58IRS2-1", "sequence": { "sequence": "MDKEPQTKAEPAKSTVNTTSTTTVNPSHQANGTPKTPPALTTVTTFHNQPSPTNRKVVQINLSGDRLAPSFSPSERVSQASSSQQTPKTISLPNTPGSTALVRGGQSAVTAVRKISPQTLLLGKSPSTSQAQMLLRAQMLQSLTIRPPPPGTLTIPPNLPLKPTTSSQPPPLSCPRIPTFHLRPSQPANAPGKDGATKSESPTSQTAQTKTPVRHLTVPPPSLYAPAQAHALAKQKLNSSSLKRPHSQISIPQHPFNQRHTPPNSPPATPKKPLPELKRCPSTQASQSISPQSASVSITVPSPARAHLTPPTLTLPLRSSSPGGSLLATKQLLRIALSSASAQCTNGQSKTATVSPPHDLIQSKPLLSPVLAKPECPTQPLLTPNTCPQLVQLSPSRQTTAATPLITTPPLASPQRASPPSPVLPLVSTSSILAPPQSPLTSQSPTQTTETSKEPKDRKEEQKQGTVPEQTPQDLKCPAPQKKMTQAVDQLPSEASEKVLNKIIVCTENSRTDGQIKTSQKNETHSPSVAPWPAEKDDQCEETSTQSDNHSAISSLSSDMSPIQSSIAQPLDMSPVDSCFPPKFHPVLERPLVQSSTLSQMKDTEGQQASGAPKPLVLTHLVEGFIIQEGLEPFPVSRSSLMVGPVQDSGVNGVKEPGLIPSGSEHPEDSTDSDDEDGVANSNGVGRAHKLVLQCQFCKRKGTAQTFPRSKRFCSKSCAKRFSYTKRFRALRRCVSEGGHRSELNGAEDSFHQAKHGATEQWRILQQPPQEGEDGTSAPMKTRLRRHTEQEREREIRVRHTVEETRSAPTSPIDPVSPTDITPYPKPAQWTVDQVSSFISKLPGCQDIAESFRAQEIDGQALLLLTEDHLMSAMNVKLGPALKICARINSLREGGR", "length": 896, "header": "tr|A0AC58IRS2-1|A0AC58IRS2_DANRE Computationally mapped isoform of Polyhomeotic-like protein 3 isoform X4 OS=Danio rerio OX=7955 GN=si:ch211-230g15.5 PE=4 SV=1 CANONICAL=A0A8M6Z4S8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 191, "start_aa": "Thr", "end_pos": 191, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr191", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:556561", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556561", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4S8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4S8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4S8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8" } ], "pmid": "" }, { "name": "PRC1 complex", "id": "GO:0035102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035102", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4S8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4S8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 586, "end_pos": 588, "annotation": "n_glycosylation_sequon" }, { "start_pos": 613, "end_pos": 615, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z4S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4S8" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 894, "end_pos": 958, "start_aa": "Trp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 191 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 302, "end_pos": 304 }, { "start_pos": 35, "end_pos": 37 }, { "start_pos": 49, "end_pos": 51 }, { "start_pos": 586, "end_pos": 588 }, { "start_pos": 613, "end_pos": 615 }, { "start_pos": 79, "end_pos": 81 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P642-1", "uniprot_ac": "A0A8M9P642", "uniprot_id": "A0A8M9P642_DANRE", "mass": { "chemical_mass": 101429.0, "monoisotopic_mass": 101429.0 }, "refseq": { "ac": "XP_021325987", "name": "villin-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325987" }, "gene_names": [ { "name": "vill", "type": "recommended", "evidence": [ { "id": "A0A8M9P642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642" } ] }, { "name": "vill", "type": "synonym", "evidence": [ { "id": "XP_021325987", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325987" } ] } ], "protein_names": [ { "name": "Villin-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642/entry#names_and_taxonomy" } ] }, { "name": "villin-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325987", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325987" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325987", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325987" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P642", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "vill", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081222-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P642", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P642", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11288", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11288", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11289", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11289", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11290", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11290", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11291", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11291", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11292", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11292", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11293", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11293", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "555361", "url": "https://www.ncbi.nlm.nih.gov/gene/555361", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036180", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036180", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:555361", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555361", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FTIWRIE", "url": "https://omabrowser.org/oma/group/FTIWRIE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AP84", "url": "https://www.orthodb.org/?gene=A0A8M3AP84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P642", "url": "https://www.orthodb.org/?gene=A0A8M9P642", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11977", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11977", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11977:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11977:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00626", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00626", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02209", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02209", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325987", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325987", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3AP84", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AP84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AP84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AP84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P642", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P642-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PM91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PM91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR72", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR72-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR88", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR88", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR88-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR88-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR97", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR97-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081222-1", "url": "https://zfin.org/ZDB-GENE-081222-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEIYIGISAKLLCLLTLAAEKGLDSKSLSLISTKRKTQFIHTVQHQPQQHLCLTHTEFSRMTEAHDLFKNIQRKPGLQIWTINKMQMVAVPEQAFGNFFEGDCYIILNVSNNPAQSIDIHYWIGNSSSQDEQGAAAIYVTQLDENFGGSPVQYREVQGHESVKFKSYFKNGLIYKKGGVASGFTHVETNVYNIQRLLHVKGTKHVTGREVEVSWNSFNLGDVFLLDLGKAIIQWNGPQSNRQEKLKAVMLAQDIRDRERGGRAQIGVIEGAQEEASPELMKVMVSVLGQRIGQMKEAIPDDKPGQNQISNVKLYQVSDASGQLLVQEVAVSPLTQDLLCSSDCYILDQGGTSIMVWKGKGASNEERRSAMGRAVGFIKAKNYPASTKVEVMSEGGESAMFKQLFKSWTEKGQTQGLGKTHSVGKIAKVDQVKFDVMELHAQPKLAAQERMVDDASGQVQVWRIENLELKEVDRSTYGQFYGGDCYLVLYTYNRANKPQYILYIWQGRHATQDEVTASAYQAVNLDNKYNGAPTQVRVVMGKEPRHFMAIFKGRLIIFEGGTGRSGVVNPDPAARLFQVRGTHELNTKATEVPARASSLNTNDVFLLKTYQTVFLWYGKGCSGDEREMGKAVADLLSGQDKQTVMEGQEPAAFWVPLGGKAPYASDKRLEEEVSLHEPRLFECSNQTGRFLMTEVADFTQDDLDEDDVMLLDTWDEIFLWIGNSANQYEIQESSSSAVEYLKTHPAGRDAGTPITTVKQGYEPPTFTGWFNAWDAHKWSGGLSYEEMKSKLGDVSQITVSLNNTDLNKKPGGGVGNYSAPGGPGSIRSHNQRMSSVQFGDGSQNRAKPSGMQNSEQLVKMPNQLPQGLDPEKREEYLSDAEFENLLGCTRANFQRLPKWRQNDLKKKAGLF", "length": 910, "header": "tr|A0A8M9P642-1|A0A8M9P642_DANRE Isoform 1 of Villin-like protein isoform X1 OS=Danio rerio OX=7955 GN=vill PE=3 SV=1 CANONICAL=A0A8M9P642-1" }, "isoforms": [ { "isoform_ac": "A0A8M3AP84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642/entry#A0A8M3AP84-1", "sequence": { "sequence": "MTEAHDLFKNIQRKPGLQIWTINKMQMVAVPEQAFGNFFEGDCYIILNVSNNPAQSIDIHYWIGNSSSQDEQGAAAIYVTQLDENFGGSPVQYREVQGHESVKFKSYFKNGLIYKKGGVASGFTHVETNVYNIQRLLHVKGTKHVTGREVEVSWNSFNLGDVFLLDLGKAIIQWNGPQSNRQEKLKAVMLAQDIRDRERGGRAQIGVIEGAQEEASPELMKVMVSVLGQRIGQMKEAIPDDKPGQNQISNVKLYQVSDASGQLLVQEVAVSPLTQDLLCSSDCYILDQGGTSIMVWKGKGASNEERRSAMGRAVGFIKAKNYPASTKVEVMSEGGESAMFKQLFKSWTEKGQTQGLGKTHSVGKIAKVDQVKFDVMELHAQPKLAAQERMVDDASGQVQVWRIENLELKEVDRSTYGQFYGGDCYLVLYTYNRANKPQYILYIWQGRHATQDEVTASAYQAVNLDNKYNGAPTQVRVVMGKEPRHFMAIFKGRLIIFEGGTGRSGVVNPDPAARLFQVRGTHELNTKATEVPARASSLNTNDVFLLKTYQTVFLWYGKGCSGDEREMGKAVADLLSGQDKQTVMEGQEPAAFWVPLGGKAPYASDKRLEEEVSLHEPRLFECSNQTGRFLMTEVADFTQDDLDEDDVMLLDTWDEIFLWIGNSANQYEIQESSSSAVEYLKTHPAGRDAGTPITTVKQGYEPPTFTGWFNAWDAHKWSGGLSYEEMKSKLGDVSQITVSLNNTDLNKKPGGGVGNYSAPGGPGSIRSHNQRMSSVQFGDGSQNRAKPSGMQNSEQLVKMPNQLPQGLDPEKREEYLSDAEFENLLGCTRANFQRLPKWRQNDLKKKAGLF", "length": 850, "header": "tr|A0A8M3AP84-1|A0A8M9P642_DANRE Computationally mapped isoform of Villin-like protein isoform X1 OS=Danio rerio OX=7955 GN=vill PE=3 SV=1 CANONICAL=A0A8M9P642-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P642-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642/entry#A0A8M9P642-1", "sequence": { "sequence": "MEIYIGISAKLLCLLTLAAEKGLDSKSLSLISTKRKTQFIHTVQHQPQQHLCLTHTEFSRMTEAHDLFKNIQRKPGLQIWTINKMQMVAVPEQAFGNFFEGDCYIILNVSNNPAQSIDIHYWIGNSSSQDEQGAAAIYVTQLDENFGGSPVQYREVQGHESVKFKSYFKNGLIYKKGGVASGFTHVETNVYNIQRLLHVKGTKHVTGREVEVSWNSFNLGDVFLLDLGKAIIQWNGPQSNRQEKLKAVMLAQDIRDRERGGRAQIGVIEGAQEEASPELMKVMVSVLGQRIGQMKEAIPDDKPGQNQISNVKLYQVSDASGQLLVQEVAVSPLTQDLLCSSDCYILDQGGTSIMVWKGKGASNEERRSAMGRAVGFIKAKNYPASTKVEVMSEGGESAMFKQLFKSWTEKGQTQGLGKTHSVGKIAKVDQVKFDVMELHAQPKLAAQERMVDDASGQVQVWRIENLELKEVDRSTYGQFYGGDCYLVLYTYNRANKPQYILYIWQGRHATQDEVTASAYQAVNLDNKYNGAPTQVRVVMGKEPRHFMAIFKGRLIIFEGGTGRSGVVNPDPAARLFQVRGTHELNTKATEVPARASSLNTNDVFLLKTYQTVFLWYGKGCSGDEREMGKAVADLLSGQDKQTVMEGQEPAAFWVPLGGKAPYASDKRLEEEVSLHEPRLFECSNQTGRFLMTEVADFTQDDLDEDDVMLLDTWDEIFLWIGNSANQYEIQESSSSAVEYLKTHPAGRDAGTPITTVKQGYEPPTFTGWFNAWDAHKWSGGLSYEEMKSKLGDVSQITVSLNNTDLNKKPGGGVGNYSAPGGPGSIRSHNQRMSSVQFGDGSQNRAKPSGMQNSEQLVKMPNQLPQGLDPEKREEYLSDAEFENLLGCTRANFQRLPKWRQNDLKKKAGLF", "length": 910, "header": "tr|A0A8M9P642-1|A0A8M9P642_DANRE Isoform 1 of Villin-like protein isoform X1 OS=Danio rerio OX=7955 GN=vill PE=3 SV=1 CANONICAL=A0A8M9P642-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PM91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642/entry#A0A8M9PM91-1", "sequence": { "sequence": "MEIYIGISAKLLCLLTLAAEKGLDSKSLSLISTKRKTQFIHTVQHQPQQHLCLTHTEFSRMTEAHDLFKNIQRKPGLQIWTINKMQMVAVPEQAFGNFFEGDCYIILNVSNNPAQSIDIHYWIGNSSSQDEQGAAAIYVTQLDENFGGSPVQYREVQGHESVKFKSYFKNGLIYKKGGVASGFTHVETNVYNIQRLLHVKGTKHVTGREVEVSWNSFNLGDVFLLDLGKAIIQWNGPQSNRQEKLKAVMLAQDIRDRERGGRAQIGVIEGAQEEASPELMKVMVSVLGQRIGQMKEAIPDDKPGQNQISNVKLYQVSDASGQLLVQEVAVSPLTQDLLCSSDCYILDQGGTSIMVWKGKGASNEERRSAMGRAVGFIKAKNYPASTKVEVMSEGGESAMFKQLFKSWTEKGQTQGLGKTHSVGKIAKVDQVKFDVMELHAQPKLAAQERMVDDASGQVQVWRIENLELKEVDRSTYGQFYGGDCYLVLYTYNRANKPQYILYIWQGRHATQDEVTASAYQAVNLDNKYNGAPTQVRVVMGKEPRHFMAIFKGRLIIFEGGTGRSGVVNPDPAARLFQVRGTHELNTKATEVPARASSLNTNDVFLLKTYQTVFLWYGKGCSGDEREMGKAVADLLSGQDKQTVMEGQEPAAFWVPLGGKAPYASDKRLEEEVSLHEPRLFECSNQTGRFLMTEVADFTQDDLDEDDVMLLDTWDEIFLWIGNSANQYEIQESSSSAVEYLKTHPAGRDAGTPITTVKQGYEPPTFTGWFNAWDAHKWSSLNNTDLNKKPGGGVGNYSAPGGPGSIRSHNQRMSSVQFGDGSQNRAKPSGMQNSEQLVKMPNQLPQGLDPEKREEYLSDAEFENLLGCTRANFQRLPKWRQNDLKKKAGLF", "length": 890, "header": "tr|A0A8M9PM91-1|A0A8M9PM91_DANRE Computationally mapped isoform of Villin-like protein isoform X3 OS=Danio rerio OX=7955 GN=vill PE=3 SV=1 CANONICAL=A0A8M9P642-1" }, "locus": {} }, { "isoform_ac": "A0AC58IR72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642/entry#A0AC58IR72-1", "sequence": { "sequence": "MREESRHTPDSLTSRLDSKSLSLISTKRKTQFIHTVQHQPQQHLCLTHTEFSRMTEAHDLFKNIQRKPGLQIWTINKMQMVAVPEQAFGNFFEGDCYIILNVSNNPAQSIDIHYWIGNSSSQDEQGAAAIYVTQLDENFGGSPVQYREVQGHESVKFKSYFKNGLIYKKGGVASGFTHVETNVYNIQRLLHVKGTKHVTGREVEVSWNSFNLGDVFLLDLGKAIIQWNGPQSNRQEKLKAVMLAQDIRDRERGGRAQIGVIEGAQEEASPELMKVMVSVLGQRIGQMKEAIPDDKPGQNQISNVKLYQVSDASGQLLVQEVAVSPLTQDLLCSSDCYILDQGGTSIMVWKGKGASNEERRSAMGRAVGFIKAKNYPASTKVEVMSEGGESAMFKQLFKSWTEKGQTQGLGKTHSVGKIAKVDQVKFDVMELHAQPKLAAQERMVDDASGQVQVWRIENLELKEVDRSTYGQFYGGDCYLVLYTYNRANKPQYILYIWQGRHATQDEVTASAYQAVNLDNKYNGAPTQVRVVMGKEPRHFMAIFKGRLIIFEGGTGRSGVVNPDPAARLFQVRGTHELNTKATEVPARASSLNTNDVFLLKTYQTVFLWYGKGCSGDEREMGKAVADLLSGQDKQTVMEGQEPAAFWVPLGGKAPYASDKRLEEEVSLHEPRLFECSNQTGRFLMTEVADFTQDDLDEDDVMLLDTWDEIFLWIGNSANQYEIQESSSSAVEYLKTHPAGRDAGTPITTVKQGYEPPTFTGWFNAWDAHKWSGGLSYEEMKSKLGDVSQITVSLNNTDLNKKPGGGVGNYSAPGGPGSIRSHNQRMSSVQFGDGSQNRAKPSGMQNSEQLVKMPNQLPQGLDPEKREEYLSDAEFENLLGCTRANFQRLPKWRQNDLKKKAGLF", "length": 903, "header": "tr|A0AC58IR72-1|A0AC58IR72_DANRE Computationally mapped isoform of Villin-like protein isoform X2 OS=Danio rerio OX=7955 GN=vill PE=3 SV=1 CANONICAL=A0A8M9P642-1" }, "locus": {} }, { "isoform_ac": "A0AC58IR88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642/entry#A0AC58IR88-1", "sequence": { "sequence": "MREESRHTPDSLTSRLDSKSLSLISTKRKTQFIHTVQHQPQQHLCLTHTEFSRMTEAHDLFKNIQRKPGLQIWTINKMQMVAVPEQAFGNFFEGDCYIILNVSNNPAQSIDIHYWIGNSSSQDEQGAAAIYVTQLDENFGGSPVQYREVQGHESVKFKSYFKNGLIYKKGGVASGFTHVETNVYNIQRLLHVKGTKHVTGREVEVSWNSFNLGDVFLLDLGKAIIQWNGPQSNRQEKLKAVMLAQDIRDRERGGRAQIGVIEGAQEEASPELMKVMVSVLGQRIGQMKEAIPDDKPGQNQISNVKLYQVSDASGQLLVQEVAVSPLTQDLLCSSDCYILDQGGTSIMVWKGKGASNEERRSAMGRAVGFIKAKNYPASTKVEVMSEGGESAMFKQLFKSWTEKGQTQGLGKTHSVGKIAKVDQVKFDVMELHAQPKLAAQERMVDDASGQVQVWRIENLELKEVDRSTYGQFYGGDCYLVLYTYNRANKPQYILYIWQGRHATQDEVTASAYQAVNLDNKYNGAPTQVRVVMGKEPRHFMAIFKGRLIIFEGGTGRSGVVNPDPAARLFQVRGTHELNTKATEVPARASSLNTNDVFLLKTYQTVFLWYGKGCSGDEREMGKAVADLLSGQDKQTVMEGQEPAAFWVPLGGKAPYASDKRLEEEVSLHEPRLFECSNQTGRFLMTEVADFTQDDLDEDDVMLLDTWDEIFLWIGNSANQYEIQESSSSAVEYLKTHPAGRDAGTPITTVKQGYEPPTFTGWFNAWDAHKWSSLNNTDLNKKPGGGVGNYSAPGGPGSIRSHNQRMSSVQFGDGSQNRAKPSGMQNSEQLVKMPNQLPQGLDPEKREEYLSDAEFENLLGCTRANFQRLPKWRQNDLKKKAGLF", "length": 883, "header": "tr|A0AC58IR88-1|A0AC58IR88_DANRE Computationally mapped isoform of Villin-like protein isoform X4 OS=Danio rerio OX=7955 GN=vill PE=3 SV=1 CANONICAL=A0A8M9P642-1" }, "locus": {} }, { "isoform_ac": "A0AC58IR97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642/entry#A0AC58IR97-1", "sequence": { "sequence": "MTEAHDLFKNIQRKPGLQIWTINKMQMVAVPEQAFGNFFEGDCYIILNVSNNPAQSIDIHYWIGNSSSQDEQGAAAIYVTQLDENFGGSPVQYREVQGHESVKFKSYFKNGLIYKKGGVASGFTHVETNVYNIQRLLHVKGTKHVTGREVEVSWNSFNLGDVFLLDLGKAIIQWNGPQSNRQEKLKAVMLAQDIRDRERGGRAQIGVIEGAQEEASPELMKVMVSVLGQRIGQMKEAIPDDKPGQNQISNVKLYQVSDASGQLLVQEVAVSPLTQDLLCSSDCYILDQGGTSIMVWKGKGASNEERRSAMGRAVGFIKAKNYPASTKVEVMSEGGESAMFKQLFKSWTEKGQTQGLGKTHSVGKIAKVDQVKFDVMELHAQPKLAAQERMVDDASGQVQVWRIENLELKEVDRSTYGQFYGGDCYLVLYTYNRANKPQYILYIWQGRHATQDEVTASAYQAVNLDNKYNGAPTQVRVVMGKEPRHFMAIFKGRLIIFEGGTGRSGVVNPDPAARLFQVRGTHELNTKATEVPARASSLNTNDVFLLKTYQTVFLWYGKGCSGDEREMGKAVADLLSGQDKQTVMEGQEPAAFWVPLGGKAPYASDKRLEEEVSLHEPRLFECSNQTGRFLMTEVADFTQDDLDEDDVMLLDTWDEIFLWIGNSANQYEIQESSSSAVEYLKTHPAGRDAGTPITTVKQGYEPPTFTGWFNAWDAHKWSSLNNTDLNKKPGGGVGNYSAPGGPGSIRSHNQRMSSVQFGDGSQNRAKPSGMQNSEQLVKMPNQLPQGLDPEKREEYLSDAEFENLLGCTRANFQRLPKWRQNDLKKKAGLF", "length": 830, "header": "tr|A0AC58IR97-1|A0AC58IR97_DANRE Computationally mapped isoform of Villin-like protein isoform X6 OS=Danio rerio OX=7955 GN=vill PE=3 SV=1 CANONICAL=A0A8M9P642-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:555361", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555361", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9P366-1", "protein_name": "Gelsolin", "gene_name": "gsna", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVYHPEFERAGKEPGLQVWRIEKFDLVAVPENLYGGFYTGDAYLVLKTIKQTSGNLQYDLHFWLGDYCTQDESGSAAIFTVQMDDYLGGKPIQYREVQGHESKSFLGYFKKGLQYMQGGVASGFKHVVTNEVVMQRVLQVKGRRVVRATEVPVSWDSFNQGDCFILDLGNEIYQWCGSKSNRFEKLKATQLAKGIRDNERSGRARVYVCDEGVEREKMLEVLGEKPDLPEGASDDVKADASNRKMAKLYKVSDASGDMAIALVAAENPFTQSALESSDCFILDHGSDGKIFVWKGKDANMEERKAAMKAADEFIKKMGYPKHTQVQILPEMGETPLFKQFFKNWRDVDQTEGMGVAYVSNSIAKIEKVPFDASTLHDSPAMAAQHGMIDSGNGEKQIWRIEGSDKVPVDPSTYGQFYGGDSYIILYSYRHGGRQGHIIYIWQGADSTQDEIGASAILGAQLDDELGGGPVQMAGAPLTTQVRVVQGKEPAHLMSLFGGQPMVVHKGGTSREGGQTAPAETRLFQVRSNSAGCTRAVEIDAVSSNLNSNDAFVLVTPAASFIWVGQGASDIEKRGAQQLCGILGVSPSELSEGGEDGGFWDALGGKAAYRTSSRLKDKMNAHPPRLFACSNKTGRFIIEEVPGEMTQEDLATDDVMILDTWDQVFVWIGNEAHDEEKMEAMTSAAQYIQTDPANRDPRTAIVKIKQGFEPPTFTGWFLGWDHDYWSTDPLERAMAELEI", "length": 738 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PW43-1", "protein_name": "Macrophage-capping protein", "gene_name": "capgb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEPDSDSMPEQAEGALQMQPFQAAPGQFGDEVRQPGLYCWRVEKMKAVPLNQAEVGAFFNGDSYLVLDNRGDQGADLHMWIGEKSSRDEQVACAMLATQLDNFLGGDPVQHRQVQGYESPEFMKLFPRGVSYKEGGVESGFRRAQSGPGPVQRLYQIKGKRNIRAKEVDLSWQSFNKGDCFILDLGETIVSWIGSQANIFEKQKVREIASLIRDTDRHGKAQITNVNEGEETQEMLKVLGPVPELKESTPEEDSKADASNSASLYKVSDATGSMKLTKVSEKSPFAKDLLVRDDCFILDNGANGKIFVWKGSGANAEEKRVALKMADDFIQQMNYPKMKTQVEILPQGRETVIFKQFFQSWN", "length": 362 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z8F1-1", "protein_name": "Villin-like", "gene_name": "Vill", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSNQVLPAINSHRALQIWITENLKMLPLPEKAHGNFFEECCYVVLHSPKATQGGSRDLHCWIGKEASTEAQEAAVSFMHRLQQDLGDQTVLHRESQGHESDCFHSYFRPGVIYRKGGRASALKLGESNVYNVQRLLHIRGRKHVSATEVALSWNSFNKGDIFLLDLGKVMIQWNGPKASICEKARALSLTCSLRDRERGGRAQIRVVDAENKATDLMSIMEAVLGRRSGSLCASVPSNSVSQLQKANIRLYHVFEKGTDLVVQELATRPLTQDLLQEDGCYLLDQGGFKIYMWQGRKSSPEERKAAFSRAVGFIQAKGYPNYTNVEVVNDGAESTAFQQLFWTWSKELNGKKHPRQSKLMQQVNLEVGKLHTQPELAAQLRMVDDGSGKVEVWYIQGSQRQPVDPKHHGQLCSGNCYLVLYKYQKLGRVQYILYLWQGHQSTVEDVKALNCNAEELDLLHQGALVQGHVTMGREPPHFLAIFQGQLVVLQGNAGNKGGRLPISDTRLFHVQGTESHNTRTMEVPARASSLTSSDVFFLITSHVCYLWFGKGCHGDQREMARTVVTVFPGNNKETVLEGQEPLHFWEALGGRAPYPSNKRLPEEISSIQPRLFECSSHSGHLVLTEVVFFGQEDLDKYDIMLLDTCQEIFLWLGEAAGEWKKAAVAWGHEYLRTHPAERSLATPIIVVKQGREPATFTGWFVTWDPYKWTSSQSYEEMVEGSLGPGSAISEITAEVHNFQLTARPSDSEAGRPTLLAFKGSQDSPENELELGLRVDGETPSMNHTSSCSSSMINGSLPRERLMHQALEDLPQGVDPARKEVGTRPNCWKTPRDPAP", "length": 836 }, "evidence": [ { "id": "HGNC:30906", "url": "https://alliancegenome.org/gene/HGNC:30906#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081222-1#orthology", "database": "AGR" }, { "id": "MGI:1201781", "url": "https://alliancegenome.org/gene/MGI:1201781#orthology", "database": "AGR" }, { "id": "RGD:1304843", "url": "https://alliancegenome.org/gene/RGD:1304843#orthology", "database": "AGR" }, { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PU64-1", "protein_name": "Scinderin", "gene_name": "Scin", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQELQHPEFARAGKQAGLQVWRVEKLELVPVPQGAYGDFYVGDAYLVLHTTKSSRGFSYRLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDFVGYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWQSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKASQVATGIRDNERKGRSQLIVVEEGSEPPELMKVLGRKPELPDGDNDDDVIADISNRKMAKLYMVSDASGSMKVTLVAEENPFSMGMLLPEECFILDHGAAKQIFVWKGKNANPQERKTAMKTAEEFLHKMNYSANTQIQVLPEGGETPIFKQFFKDWKDKDQSDGFGKVYITEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGGVEIWRVENSGRVQIDPSSYGEFYGGDCYIILYTYPRGQIIYTWQGADATRDELTMSAFLTVQLDRSLGGQAVQVRVSQGKEPAHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDTFVLKLPRNNGFIWIGKGASQEEEKGAEYVADVLKCKTTRIQEGKEPGMNSGTLLEEEETTRLHHCWKHRLKIILLGFMAALTKLEDSLLKKFRESSPRMTWPKMMSCYLMRGNRSSFGLAKMPMKLRKRNQ", "length": 671 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QVU3-1", "protein_name": "Villin-1", "gene_name": "vil1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPQEVKTDVPKVLNKTTPGLQIWRVENMELVPCPSKTFGQFFEGDSYVILYTHKTSNNFSYDIHYWLGKSTSQDEMGAAAIYTTQMDDHLGGVAVQHRETQGHESATFQGYFKQGIIYKKGGVASGMKQVETNTYNIRRLLHVKGNKHVVAGEVEMSWNSFNKGDVFLLDLGSLIIQWNGPKSNRMERLRGMNLAKDIRDRERGGRAQVAVVEGDDEQSSEEAMKLMKQSLGERPKNIKEAIPDEIVDEKLKTAIKLYHISDAQGSLVVQEVAVKPLTQDLLKTEDCYLLDQGGIKIFIWKGKKASKAERTESLKMAEAYVKAKGYPVSTYIETVSEGAESSVFKQLFQKWTDKGQTVGMGTTHNPGKIAKVEQVKFDATSMHARPDIAAQQKMVDDGSGEAEVWRIEDNELAPVDRKWLGHFYGGDCYLILYKYEVSSKFHYILYMWQGRHASTAELTACAYQAVILDQKYNGEPVQVRVPMGKEPMHLMAIFKGKMIVYEEGSSREGSSQSRPSVRLFHVHGTNEFNTRATEVPPRSSSLNSNDVFVLSTDKCCYLWYGKGCSGDEREMAKSLADIISKREKQVIAEGQEPADFWVNLGGKSQYASNKRLQDENISITPRLFECSNQTGRFIATEITNFNQDDLDEDDVMLLDIWDQVYLWIGKGANDTEKREAVVTAQEYLKSHPAGRDLDTPVLVVKQGFEPPTFTGWFHAWDPQKWSEGKSYDQLKAELGDATDVIKITVDLTQPSSNQTNSSNSTQGGSMPRPVTQTFPAEKLVNVQTEDLPEGVDPTRKEDYLSDDDFALAMGISRMNFYAMPSWKQLNLKKEKGLF", "length": 834 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O15195-1", "protein_name": "Villin-like protein", "gene_name": "VILL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDISKGLPGMQGGLHIWISENRKMVPVPEGAYGNFFEEHCYVILHVPQSPKATQGASSDLHYWVGKQAGAEAQGAAEAFQQRLQDELGGQTVLHREAQGHESDCFCSYFRPGIIYRKGGLASDLKHVETNLFNIQRLLHIKGRKHVSATEVELSWNSFNKGDIFLLDLGKMMIQWNGPKTSISEKARGLALTYSLRDRERGGGRAQIGVVDDEAKAPDLMQIMEAVLGRRVGSLRAATPSKDINQLQKANVRLYHVYEKGKDLVVLELATPPLTQDLLQEEDFYILDQGGFKIYVWQGRMSSLQERKAAFSRAVGFIQAKGYPTYTNVEVVNDGAESAAFKQLFRTWSEKRRRNQKLGGRDKSIHVKLDVGKLHTQPKLAAQLRMVDDGSGKVEVWCIQDLHRQPVDPKRHGQLCAGNCYLVLYTYQRLGRVQYILYLWQGHQATADEIEALNSNAEELDVMYGGVLVQEHVTMGSEPPHFLAIFQGQLVIFQERAGHHGKGQSASTTRLFQVQGTDSHNTRTMEVPARASSLNSSDIFLLVTASVCYLWFGKGCNGDQREMARVVVTVISRKNEETVLEGQEPPHFWEALGGRAPYPSNKRLPEEVPSFQPRLFECSSHMGCLVLAEVGFFSQEDLDKYDIMLLDTWQEIFLWLGEAASEWKEAVAWGQEYLKTHPAGRSPATPIVLVKQGHEPPTFIGWFFTWDPYKWTSHPSHKEVVDGSPAAASTISEITAEVNNLRLSRWPGNGRAGAVALQALKGSQDSSENDLVRSPKSAGSRTSSSVSSTSATINGGLRREQLMHQAVEDLPEGVDPARREFYLSDSDFQDIFGKSKEEFYSMATWRQRQEKKQLGFF", "length": 856 }, "evidence": [ { "id": "HGNC:30906", "url": "https://alliancegenome.org/gene/HGNC:30906#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081222-1#orthology", "database": "AGR" }, { "id": "MGI:1201781", "url": "https://alliancegenome.org/gene/MGI:1201781#orthology", "database": "AGR" }, { "id": "RGD:1304843", "url": "https://alliancegenome.org/gene/RGD:1304843#orthology", "database": "AGR" }, { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O75366-1", "protein_name": "Advillin", "gene_name": "AVIL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLTSAFRAVDNDPGIIVWRIEKMELALVPVSAHGNFYEGDCYVILSTRRVASLLSQDIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKQGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNRGDVFLLDLGKVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAKIGVIEGDKEAASPELMKVLQDTLGRRSIIKPTVPDEIIDQKQKSTIMLYHISDSAGQLAVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKAEKQAAMSKALGFIKMKSYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTMGLGKTFSIGKIAKVFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWYGFFYGGDCYLVLYTYEVNGKPHHILYIWQGRHASQDELAASAYQAVEVDRQFDGAAVQVRVRMGTEPRHFMAIFKGKLVIFEGGTSRKGNAEPDPPVRLFQIHGNDKSNTKAVEVPAFASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELASLLCDGSENTVAEGQEPAEFWDLLGGKTPYANDKRLQQEILDVQSRLFECSNKTGQFVVTEITDFTQDDLNPTDVMLLDTWDQVFLWIGAEANATEKESALATAQQYLHTHPSGRDPDTPILIIKQGFEPPIFTGWFLAWDPNIWSAGKTYEQLKEELGDAAAIMRITADMKNATLSLNSNDSEPKYYPIAVLLKNQNQELPEDVNPAKKENYLSEQDFVSVFGITRGQFAALPGWKQLQMKKEKGLF", "length": 819 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O81645-1", "protein_name": "Villin-3", "gene_name": "VLN3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSGSTKVLDPAFQGVGQKPGTEIWRIENFEPVPVPKSEHGKFYMGDTYIVLQTTQNKGGAYLFDIHFWIGKDTSQDEAGTAAVKTVELDAALGGRAVQYREIQGHESDKFLSYFKPCIIPLEGGVASGFKKPEEEEFETRLYTCKGKRAVHLKQVPFARSSLNHDDVFILDTKEKIYQFNGANSNIQERAKALVVIQYLKDKFHEGTSDVAIVDDGKLDTESDSGEFWVLFGGFAPIARKVASEDEIIPETTPPKLYSIADGQVESIDGDLSKSMLENNKCYLLDCGSEIFIWVGRVTQVEERKTAIQAAEDFVASENRPKATRITRVIQGYEPHSFKSNFDSWPSGSATPANEEGRGKVAALLKQQGVGLKGLSKSTPVNEDIPPLLEGGGKLEVWYIDANSKTVLSKDHVGKLYSGDCYLVLYTYHSGERKEDYFLCCWFGKNSNQEDQETAVRLASTMTNSLKGRPVQARIFEGKEPPQFVALFQHMVVLKGGLSSGYKNSMTEKGSSGETYTPESIALIQVSGTGVHNNKALQVEAVATSLNSYDCFLLQSGTSMFLWVGNHSTHEQQELAAKVAEFLKPGTTIKHAKEGTESSSFWFALGGKQNFTSKKVSSETVRDPHLFSFSFNRGKFQVEEIHNFDQDDLLTEEMHLLDTHAEVFVWVGQCVDPKEKQTAFEIGQRYINLAGSLEGLSPKVPLYKITEGNEPCFFTTYFSWDSTKATVQGNSYQKKAALLLGTHHVVEDQSSSGNQGPRQRAAALAALTSAFNSSSGRTSSPSRDRSNGSQGGPRQRAEALAALTSAFNSSPSSKSPPRRSGLTSQASQRAAAVAALSQVLTAEKKKSPDTSPSAEAKDEKAFSEVEATEEATEAKEEEEVSPAAEASAEEAKPKQDDSEVETTGVTFTYERLQAKSEKPVTGIDFKRREAYLSEVEFKTVFGMEKESFYKLPGWKQDLLKKKFNLF", "length": 965 }, "evidence": [ { "id": "A0A8M9P642", "url": "https://omabrowser.org/oma/group/A0A8M9P642/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O88398-1", "protein_name": "Advillin", "gene_name": "Avil", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLSSAFRAVSNDPRIITWRIEKMELALVPLSAHGNFYEGDCYIVLSTRRVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPGLMTVLQDTLGRRSMIKPAVSDEIMDQQQKSSIMLYHVSDTAGQLSVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTGLGKIFSTGKIAKIFQDKFDVSLLHTKPEVAAQERMVDDGKGQVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNGKPHYILYIWQGRHASRDELAASAYRAVEVDQQFDGAPVQVRVSMGKEPRHFMAIFKGKLVIYEGGTSRKGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELVDLLCDGNADTVAEGQEPPEFWDLLGGKTAYANDKRLQQETLDVQVRLFECSNKTGRFLVTEVTDFTQEDLSPGDVMLLDTWDQVFLWIGAEANATEKKGALSTAQEYLVTHPSGRDPDTPILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELGDATAIVRITADMKNATLYLNPSDGEPKYYPVEVLLKGQNQELPEDVDPAKKENYLSEQDFVSVFGITRGQFTALPGWKQLQLKKERGLF", "length": 819 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06396-1", "protein_name": "Gelsolin", "gene_name": "GSN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPHRPAPALLCALSLALCALSLPVRAATASRGASQAGAPQGRVPEARPNSMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPTNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESATFLGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWESFNNGDCFILDLGNNIHQWCGSNSNRYERLKATQVSKGIRDNERSGRARVHVSEEGTEPEAMLQVLGPKPALPAGTEDTAKEDAANRKLAKLYKVSNGAGTMSVSLVADENPFAQGALKSEDCFILDHGKDGKIFVWKGKQANTEERKAALKTASDFITKMDYPKQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGLGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSREGGQTAPASTRLFQVRANSAGATRAVEVLPKAGALNSNDAFVLKTPSAAYLWVGTGASEAEKTGAQELLRVLRAQPVQVAEGSEPDGFWEALGGKAAYRTSPRLKDKKMDAHPPRLFACSNKIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVKQGFEPPSFVGWFLGWDDDYWSVDPLDRAMAELAA", "length": 782 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P09327-1", "protein_name": "Villin-1", "gene_name": "VIL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKLSAQVKGSLNITTPGLQIWRIEAMQMVPVPSSTFGSFFDGDCYIILAIHKTASSLSYDIHYWIGQDSSLDEQGAAAIYTTQMDDFLKGRAVQHREVQGNESEAFRGYFKQGLVIRKGGVASGMKHVETNSYDVQRLLHVKGKRNVVAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESTRMERLRGMTLAKEIRDQERGGRTYVGVVDGENELASPKLMEVMNHVLGKRRELKAAVPDTVVEPALKAALKLYHVSDSEGNLVVREVATRPLTQDLLSHEDCYILDQGGLKIYVWKGKKANEQEKKGAMSHALNFIKAKQYPPSTQVEVQNDGAESAVFQQLFQKWTASNRTSGLGKTHTVGSVAKVEQVKFDATSMHVKPQVAAQQKMVDDGSGEVQVWRIENLELVPVDSKWLGHFYGGDCYLLLYTYLIGEKQHYLLYVWQGSQASQDEITASAYQAVILDQKYNGEPVQIRVPMGKEPPHLMSIFKGRMVVYQGGTSRTNNLETGPSTRLFQVQGTGANNTKAFEVPARANFLNSNDVFVLKTQSCCYLWCGKGCSGDEREMAKMVADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRLQEENLVITPRLFECSNKTGRFLATEIPDFNQDDLEEDDVFLLDVWDQVFFWIGKHANEEEKKAAATTAQEYLKTHPSGRDPETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYEDLKAELGNSRDWSQITAEVTSPKVDVFNANSNLSSGPLPIFPLEQLVNKPVEELPEGVDPSRKEEHLSIEDFTQAFGMTPAAFSALPRWKQQNLKKEKGLF", "length": 827 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13020-1", "protein_name": "Gelsolin", "gene_name": "Gsn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPYRSSLLCALLLLALCALSPSHAATTSRGRAQERAPQSRVSEARPSTMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFSGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSGRAQVHVSEEGGEPEAMLQVLGPKPALPEGTEDTAKEDAANRRLAKLYKVSNGAGSMSVSLVADENPFAQGALRSEDCFILDHGRDGKIFVWKGKQANMEERKAALKTASDFISKMQYPRQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGPGLGYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVPVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSRDGGQTAPASIRLFQVRASSSGATRAVEVMPKSGALNSNDAFVLKTPSAAYLWVGAGASEAEKTGAQELLKVLRSQHVQVEEGSEPDAFWEALGGKTAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVRQGFEPPSFVGWFLGWDDNYWSVDPLDRALAELAA", "length": 780 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P24452-1", "protein_name": "Macrophage-capping protein", "gene_name": "Capg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYTPIPQSGSPFPASVQDPGLHIWRVEKLKPVPIARESHGIFFSGDSYLVLHNGPEEASHLHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYYREGGVESAFHKTTSGARGAAIRKLYQVKGKKNIRATERPLSWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIITDGEEPAEMIQVLGPKPALKEGNPEEDITADQTRPNAQAAALYKVSDATGQMNLTKVADSSPFASELLIPDDCFVLDNGLCAQIYIWKGRKANEKERQAALQVADGFISRMRYSPNTQVEILPQGRESPIFKQFFKNWK", "length": 352 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P40121-1", "protein_name": "Macrophage-capping protein", "gene_name": "CAPG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYTAIPQSGSPFPGSVQDPGLHVWRVEKLKPVPVAQENQGVFFSGDSYLVLHNGPEEVSHLHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPRGLKYQEGGVESAFHKTSTGAPAAIKKLYQVKGKKNIRATERALNWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIVTDGEEPAEMIQVLGPKPALKEGNPEEDLTADKANAQAAALYKVSDATGQMNLTKVADSSPFALELLISDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVAEGFISRMQYAPNTQVEILPQGHESPIFKQFFKDWK", "length": 348 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q07171-1", "protein_name": "Gelsolin", "gene_name": "Gel", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDASGAATMAVLSSLLVFLALSSSLCSAGTLNARPAFPVQSGEIQPSGQNSKQAARRVMHPSFANAGRTPGLEIWRIENFEPVIYPKTNYGKFYTGDSFIVLNTIENKKDKKLSWDVHFWLGLETSTDEAGAAAILTVQLDDLLNGGPVQHREVQDHESQLFLSYFKNGIRYEQGGVGTGFKHVETNAQGETRLFQVKGKRNVRVRQVNLSVSSMNTGDCFILDAGSDIYVYVGSQAKRVEKLKAISAANQIRDQDHNGRARVQIVDDFSTDADKQHFFDVLGSGSADQVPDESTADEDSAFERTDAAAVSLYKVSDASGKLKVDIIGQKPLTQAMLDTRECFILDTGSGIFVWVGKGATQKEKTDAMAKAQEFLRTKKYPAWTQIHRIVEGSESAPFKQYFDTWRDAGMSHSRLIRSALGIGSDELLNDDEIDSVVTQLKKSGGRAFGFMPDHGQNVIETITQYVAKPGSDEIVVSTVPFDEKLPLLGFASYVLTYNYEANNGDTGSLTYVWHGVKASAAARKRAFEEGLVGSKDGLLVQTNQGHEPRHFYKIFKGKLLTSFTALPVTAQLFRIRGTVESDVHASEVAADSSSLASSDAFVLHSGKSHKIYIWNGLGASAFEKQAAVDRFSDYWDDVELEQVEEGAEPDEFWEELNGEGQYDRSLGDDGAPLLESRLFHCHLSSGGFLKVEEVAQYEQEDLDSDDIMLLDAGDEIYLWVGYGVSEEENGKLLDTAKLYFNLEPTARSFDTVSIIRVPQGKEPRVFKRMFPNWDDNYWQNQPSYEDMKQLVIDANNEV", "length": 798 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-081222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081222-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q23989-1", "protein_name": "Villin-like protein quail", "gene_name": "qua", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MELSLSPKETEIRPNTIPDLKVDATFRKVAKHAITFAIWKIDEDRLEAVQRSHYGTFYDSCAYIIYAASLSGHYANHETITREQKPNVSLERYIHYWLGKNVSEQNRSNVVHKIQELDSYLGNISSIYRETQNLESARFLSYFKKGYDVRSGALISAPQRPRLFQLYARKWLRSIEVATIDWSHFNSDYVMVLQTDNLTYVWIGRSSSGIERRSALDWVQKHCSGSPITIVDDGYEQAMSQEHKELWNTMLPLKKRMVCQASQLVSEYADYNSNKFRIYKCNQRGRLHLDQLDVGMPAKDDLSDAHGVYLLDNYGQSIWLWVGGQAPQADALSAMGNGRAFVKKKKYPDNTLVVRVLEGHEPVEFKRLFANWLNVWQENTRGHKPVSTKFGKLDAHSLCERPKMAADTQLVDDGRGERVIYRVFGDQVQEVPISKTVVFTTNASFVVKYSVQCATVVPADLASVGIKTIIYQWNGSEASVESISRADKFAKASFDGLKEPGMFVQLYEFDEPPHFLQIFEGKLIIRRGQRTEMPYNGNSNALLDTFLLKVYGDASYNAKAVEETHLSSISSKDCYVIKTNHVWVWCGQSSTGDAREMAKAVGALMGENSLVLEGKESKEFWQSVAMYFNQTLVINGNGNSCSSSTSSSSGAGSMCNGSSNGGNISPTLSNNCYLNTSVPSKPRPPVQLFLVWWQQSSLRYEEILGFDQQDLSSDCTYILDTGSLTYVWLGSQAPNQERYTAIAQSYVQNAPFGRRSATALAVVRQFQEPNVFKGFFESWQNDYGKNFHSYEKMRKDLGNKVTSNCCFASEGSALILNNRQKDFDGHKKYPLTVLIQEMDMLPPDINPLKREVHLTHDDFVSVFNMSFYEFDELPKWKKMELKKQFKLF", "length": 888 }, "evidence": [ { "id": "HGNC:30906", "url": "https://alliancegenome.org/gene/HGNC:30906#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081222-1#orthology", "database": "AGR" }, { "id": "MGI:1201781", "url": "https://alliancegenome.org/gene/MGI:1201781#orthology", "database": "AGR" }, { "id": "RGD:1304843", "url": "https://alliancegenome.org/gene/RGD:1304843#orthology", "database": "AGR" }, { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q60604-1", "protein_name": "Scinderin", "gene_name": "Scin", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQELQHPEFARAGQQAGLQVWRVEKLELVPVPQGAYGDFYVGDAYLVLHTTKSSRGFSYRLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQSRELQGYESTDFVGYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWESFNKGDCFIIDLGTEIYQWCGSSCNKYERLKASQVAIGIRDNERKGRSQLIVVEEGSEPSELMKVLGRKPELPDGDNDDDVVADISNRKMAKLYMVSDASGSMKVTLVAEENPFSMGMLLSEECFILDHGAAKQIFVWKGKNANPQERKTAMKTAEEFLQKMKYSTNTQIQVLPEGGETPIFKQFFKDWKDKDQSDGFGKVYITEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGGVEIWRVENSGRVQIDPSSYGEFYGGDCYIILYTYPRGQIIYTWQGANATRDELTMSAFLTVQLDRSLGGQAVQVRVSQGKEPAHLLSLFKDKPLIIYKNGTSKKEGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDTFVLKLPRNNGFIWIGKGASQEEEKGAEYVADVLKCKASRIQEGKEPEEFWNSLGGRGDYQTSPLLETRAEDHPPRLYGCSNKTGRFIIEEVPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESVKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSRW", "length": 715 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62468-1", "protein_name": "Villin-1", "gene_name": "Vil1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKLNAQVKGSLNITTPGIQIWRIEAMQMVPVPSSTFGSFFDGDCYVVLAIHKTSSTLSYDIHYWIGQDSSQDEQGAAAIYTTQMDDYLKGRAVQHREVQGNESETFRSYFKQGLVIRKGGVASGMKHVETNSCDVQRLLHVKGKRNVLAGEVEMSWKSFNRGDVFLLDLGKLIIQWNGPESNRMERLRGMALAKEIRDQERGGRTYVGVVDGEKEGDSPQLMAIMNHVLGPRKELKAAISDSVVEPAAKAALKLYHVSDSEGKLVVREVATRPLTQDLLKHEDCYILDQGGLKIFVWKGKNANAQERSGAMSQALNFIKAKQYPPSTQVEVQNDGAESPIFQQLFQKWTVPNRTSGLGKTHTVGSVAKVEQVKFDALTMHVQPQVAAQQKMVDDGSGEVQVWRIEDLELVPVESKWLGHFYGGDCYLLLYTYLIGEKQHYLLYIWQGSQASQDEIAASAYQAVLLDQKYNDEPVQIRVTMGKEPPHLMSIFKGRMVVYQGGTSRKNNLEPVPSTRLFQVRGTNADNTKAFEVTARATSLNSNDVFILKTPSCCYLWCGKGCSGDEREMAKMVADTISRTEKQVVVEGQEPANFWMALGGKAPYANTKRLQEENQVITPRLFECSNQTGRFLATEIFDFNQDDLEEEDVFLLDVWDQVFFWIGKHANEEEKKAAATTVQEYLKTHPGNRDLETPIIVVKQGHEPPTFTGWFLAWDPFKWSNTKSYDDLKAELGNSGDWSQIADEVMSPKVDVFTANTSLSSGPLPTFPLEQLVNKSVEDLPEGVDPSRKEEHLSTEDFTRALGMTPAAFSALPRWKQQNIKKEKGLF", "length": 827 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q68FP1-1", "protein_name": "Gelsolin", "gene_name": "Gsn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPYCSSLRSALLVLALCALSPSHAATASRGRAQERAPQSRVSETRPSTMVVEHPEFLKAGKEPGLQIWRVEKFDLVPVPPNLYGDFFTGDAYVILKTVQLRNGNLQYDLHYWLGNECSQDESGAAAIFTVQLDDYLNGRAVQHREVQGFESSTFQGYFKSGLKYKKGGVASGFKHVVPNEVVVQRLFQVKGRRVVRATEVPVSWDSFNNGDCFILDLGNNIYQWCGSGSNKFERLKATQVSKGIRDNERSGRAQVHVSEEGSEPEAMLQVLGPKPDLPQGTEDTAKEDAANRRLAKLYKVSNSGGSMSVSLVADENPFAQSALRSEDCFILDHGRDGKIFVWKGKQANMDERKAALKTASDFISKMQYPRQTQVSVLPEGGETPLFKQFFKNWRDPDQTDGPGLSYLSSHIANVERVPFDAATLHTSTAMAAQHGMDDDGTGQKQIWRIEGSNKVLVDPATYGQFYGGDSYIILYNYRHGGRQGQIIYNWQGAQSTQDEVAASAILTAQLDEELGGTPVQSRVVQGKEPAHLMSLFGGKPMIIYKGGTSRDGGQTTPASTRLFQVRASSSGATRAVEVMPKAGALNSNDAFVLKTPSAAYLWVGTGASDAEKTGALELLKVLRAQHVQVEEGSEPDGFWEALGGKTAYRTSPRLKDKKMDAHPPRLFACSNRIGRFVIEEVPGELMQEDLATDDVMLLDTWDQVFVWVGKDSQEEEKTEALTSAKRYIETDPANRDRRTPITVVRQGFEPPSFVGWFLGWDDDYWSVDPLDRALAELAA", "length": 780 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AYC4-1", "protein_name": "Macrophage-capping protein", "gene_name": "Capg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYTPIPQSGSPFPASVQDPGLHIWRVEKLKPVPIARENHGIFFSGDSYLVLHNGPEEASHLHLWIGQQSSRDEQGACAVLAVHLNTLLGERPVQHREVQGNESDLFMSYFPQGLKYREGGVESAFHKTTSGTTPAAIRKLYQVKGKKNIRATERALSWDSFNTGDCFILDLGQNIFAWCGGKSNILERNKARDLALAIRDSERQGKAQVEIITDGEEPAEMIQVLGPKPALKEGNPEEDITADQTNAQAAALYKVSDATGQMNLTKVADSSPFASELLIPDDCFVLDNGLCGKIYIWKGRKANEKERQAALQVADGFISRMRYSPNTQVEILPQGRESPIFKQFFKDWK", "length": 349 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91YD6-1", "protein_name": "Villin-like protein", "gene_name": "Vill", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDINQDLPAIDSHRALQIWITENLKMLPLPERAHGNFFEECCYVVLHVPQSPKATQGGSSDLHYWIGKDASAEAREAAVSFVQCLQEDLGDQTVLHRESQGHESDCFHSYFHPGVIYRKGGRDSALKFAETNMYNVQRLLHIKGRKHVSATEVALSWNSFNKGDIFLLDLGKVMIQWNGPKASISEKARALTLTCNLRDRERGGRAQIAVVDAENEATNLLRIMEAVLGCRSGSLCPSVPSNSVSQLQKANVRLYHVCEKGTDLVVQELATRPLTQDLLQEDGCYLLDQGGFKIYMWQGRKSSPQEKKAALSRAVGFIQAKGYPNYTNVEVVNDGAESTAFQQLFWSWSKELDRKKHPEKSKLVQGNLEVGKLHTQPELAAQLRMVDDGSGKVEVWYIQDLQRQPVHPKYYGQLCSGNCYLVLYTYQKLGCVQYLLYLWQGHQSTVEDTKALNCSAEELDLMHQGALAQGHVTMGSEPPHFLAIFQGRLVVFQGNAGNKGERPPVSDTRLFHVQGTESHNTRTMEVPARASSLTSGDVFFLITSHVCYLWFGKGCHGDQREMARTVVSVFPGNNKETVLEGQEPLYFWEALGGRAPYPSNKRLPEEVWSIQPRLFECSSHAGCLVLTEVLFFGQEDLDKYDIMLLDTCQEIFLWLGEAAGEWKKEAVAWGLEYLRTHPAERSLATPIFVVKQGHEPATFTGWFVTWDPYKWMNSQSYEEMVGNSLGPGSAISEMTAEVHNFQLTPRLSDNKAGHPALQAFKGSQDSPENELGLDLRVDGANPSMNHTSSCSDSMVNGSLPRERLMHQALEDLPPGVDPARKEFYLSDSDFQDIFGKSKEEFYSMAKWKQQQAKKKLGFF", "length": 859 }, "evidence": [ { "id": "HGNC:30906", "url": "https://alliancegenome.org/gene/HGNC:30906#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081222-1#orthology", "database": "AGR" }, { "id": "MGI:1201781", "url": "https://alliancegenome.org/gene/MGI:1201781#orthology", "database": "AGR" }, { "id": "RGD:1304843", "url": "https://alliancegenome.org/gene/RGD:1304843#orthology", "database": "AGR" }, { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9WU06-1", "protein_name": "Advillin", "gene_name": "Avil", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSAFRTVTNDPGIITWRIEKMELVLVPLSAHGNFYEGDCYIILSTRRVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKRGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIRATEVEMSWDSFNQGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPELMTVLQNTLGRRSIIKPAVPDEVTDQQQKSTIMLYHVSDTTGQLSVTEVATRPLVQELLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTGLGKTFSIGKIAKIFQDKFDVTLLHTKPEVAAQERMVDDGNGKVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNGKPCYILYIWQGRHASQDELAASAYQAVEVDQQFGGAPVQVRVSMGKEPRHFMAIFKGKLVIYEGGTSRKGNVEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLWTQAEHYLWYGKGSSGDERAMAKELAELLCDGDADTVAEGQEPPEFWDLLGGKAPYANDKRLQQETLDIQVRLFECSNKTGRFLVTEVTDFTQDDLSPGDVMLLDTWDQVFLWIGAEANATEKEGALSTAQEYLVTHPSGRDPDTPILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELGDATAIVRITTDMKNATLSLNSSESGPKYYPVEVLLKSQDQELPEDVDPTKKENYLSERDFVSVFGITRGQFVSLPGWKQLQLKKEAGLF", "length": 819 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y6U3-1", "protein_name": "Scinderin", "gene_name": "SCIN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARELYHEEFARAGKQAGLQVWRIEKLELVPVPQSAHGDFYVGDAYLVLHTAKTSRGFTYHLHFWLGKECSQDESTAAAIFTVQMDDYLGGKPVQNRELQGYESNDFVSYFKGGLKYKAGGVASGLNHVLTNDLTAKRLLHVKGRRVVRATEVPLSWDSFNKGDCFIIDLGTEIYQWCGSSCNKYERLKANQVATGIRYNERKGRSELIVVEEGSEPSELIKVLGEKPELPDGGDDDDIIADISNRKMAKLYMVSDASGSMRVTVVAEENPFSMAMLLSEECFILDHGAAKQIFVWKGKDANPQERKAAMKTAEEFLQQMNYSKNTQIQVLPEGGETPIFKQFFKDWRDKDQSDGFGKVYVTEKVAQIKQIPFDASKLHSSPQMAAQHNMVDDGSGKVEIWRVENNGRIQVDQNSYGEFYGGDCYIILYTYPRGQIIYTWQGANATRDELTTSAFLTVQLDRSLGGQAVQIRVSQGKEPVHLLSLFKDKPLIIYKNGTSKKGGQAPAPPTRLFQVRRNLASITRIVEVDVDANSLNSNDVFVLKLPQNSGYIWVGKGASQEEEKGAEYVASVLKCKTLRIQEGEEPEEFWNSLGGKKDYQTSPLLETQAEDHPPRLYGCSNKTGRFVIEEIPGEFTQDDLAEDDVMLLDAWEQIFIWIGKDANEVEKKESLKSAKMYLETDPSGRDKRTPIVIIKQGHEPPTFTGWFLGWDSSKW", "length": 715 }, "evidence": [ { "id": "FB:FBgn0003187", "url": "https://alliancegenome.org/gene/FB:FBgn0003187#orthology", "database": "AGR" }, { "id": "FB:FBgn0010225", "url": "https://alliancegenome.org/gene/FB:FBgn0010225#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P642", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P642", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P642", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642" } ], "pmid": "" }, { "name": "phosphatidylinositol-4,5-bisphosphate binding", "id": "GO:0005546", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005546", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P642", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P642", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642" } ], "pmid": "" }, { "name": "actin filament capping", "id": "GO:0051693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051693", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P642", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642" } ], "pmid": "" }, { "name": "barbed-end actin filament capping", "id": "GO:0051016", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051016", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P642", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642" } ], "pmid": "" }, { "name": "actin polymerization or depolymerization", "id": "GO:0008154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008154", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P642", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642" } ], "pmid": "" }, { "name": "actin filament severing", "id": "GO:0051014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051014", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P642", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 684, "end_pos": 686, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" }, { "start_pos": 815, "end_pos": 817, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P642" }, { "id": "PS51089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HP", "eco_id": "ECO_0000259", "start_pos": 845, "end_pos": 910, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 125, "end_pos": 127 }, { "start_pos": 684, "end_pos": 686 }, { "start_pos": 801, "end_pos": 803 }, { "start_pos": 815, "end_pos": 817 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9NYQ0-1", "uniprot_ac": "A0A8M9NYQ0", "uniprot_id": "A0A8M9NYQ0_DANRE", "mass": { "chemical_mass": 344008.0, "monoisotopic_mass": 344008.0 }, "refseq": { "ac": "XP_021322132", "name": "protein furry homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322132" }, "gene_names": [ { "name": "frya", "type": "recommended", "evidence": [ { "id": "A0A8M9NYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0" } ] }, { "name": "frya", "type": "synonym", "evidence": [ { "id": "XP_021322132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322132" } ] } ], "protein_names": [ { "name": "Protein furry homolog isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9NYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#names_and_taxonomy" } ] }, { "name": "protein furry homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322132", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322132" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322132" } ] } ], "disease": [ { "disease_id": "DOID:0050888", "recommended_name": { "id": "DOID:0050888", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050888", "name": "syndromic intellectual disability", "description": "An intellectual disability that is characterized by the presence of associated medical and behavioral sign and symptoms." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050888", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050888" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NYQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "frya", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060510-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060510-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "566822", "url": "https://www.ncbi.nlm.nih.gov/gene/566822", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025481", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025481", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039867", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039867", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045842", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045842", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566822", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566822", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M2B457", "url": "https://www.orthodb.org/?gene=A0A8M2B457", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3ASX5", "url": "https://www.orthodb.org/?gene=A0A8M3ASX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12295", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12295", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12295:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12295:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14222", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14222", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14228", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14228", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322132", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322132", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B457", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B457", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B457-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B457-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3ASX5", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ASX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3ASX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ASX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9NYQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9NYQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T1Y0", "url": "https://www.uniprot.org/uniprotkb/A0AB32T1Y0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T1Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T1Y0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T373", "url": "https://www.uniprot.org/uniprotkb/A0AB32T373", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T373-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T373-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T4M2", "url": "https://www.uniprot.org/uniprotkb/A0AB32T4M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T4M2-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T4M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T7K2", "url": "https://www.uniprot.org/uniprotkb/A0AB32T7K2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T7K2-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T7K2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD34", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD34-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD35", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD35-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD43", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD43-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD44", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD44-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD68", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD68-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD70", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD70-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060510-4", "url": "https://zfin.org/ZDB-GENE-060510-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEIQSYSERSYSELNEENDGIEVVSMASVPEDLMLSGDFRGKFKKIRYRKRASILSSSPGYTKPPVPPVCCSQGEKGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKSDIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVILRASSPDLPSSGKLTLNRKSTSQLELIPGSATASERIRHQRSYSVPKRFGEAERSSDVPRSATLDRIHHHQSNISKLRSLSSSSSRDNVVSTDPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEKNSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSPSSPQSNSSSVDVRRVWDTPSKALPGKTLDFHFDISETPVIGRRYDELHGSPRQDGKNQGVVTVTRSTSSTSSGSYQSNHVLVPVSWKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSEDGTRDTENMDDTTSEQQFRVFRDFDFLDVELEDGEGETVDSFNWGARRRSIDSLDQTEAQPLEEDSQLSGSSPSLCPIIHDDSDESSEEESLTASQILSASQLNVSLSPTEDLNPMDSPPVSFDNTQADQIPLSTSTPSFEIPLPEGSNHRAEDSAEEEEGIVNENDISLCICESPPAFSCSDILTLETPQREENFFTDEMSCVPSGFGEQFSSVAQAEEEKEELLLESRSSPPPSPFFSAILAAFQPTMCDDAEEAWRSHLNQLVADSDGSCAVYTFQVFSSLFQNIQSKFCTLTCDAAGYLGDGLRGIGAKFLRSSQMLTSCSECPTLFVDADTIVSYGLLEKMKFSVLELQEYLETYNNKKEAVISWLCNCKASFPKCSEDGVITYQPAETEEKQMEYLAQLELCQRLYKLHFQLLLLFQSYCKLIGQVHTINSVPELQNMSRELSDLRSNLRAAAASVAEENTGDRRDSSAESSFSSSEAAVQAILESLKNCDLSRAIRYIRECRKMWPSDIFGSSSENEIQTLLNIYFRHQTLGQTGTFALVGSKQDLSEICNRLTELNCEIRDMIRRAQGYRAITAFLPDSSVTGISL", "length": 3060, "header": "tr|A0A8M9NYQ0-1|A0A8M9NYQ0_DANRE Isoform 1 of Protein furry homolog isoform X1 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B457-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0A8M2B457-1", "sequence": { "sequence": "MASQQDSGFFEISIKSLLKSWSSTSPGYTKPPVPPVCCSQGEKGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKSDIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVILRASSPDLPSSGKLTLNRKSTSQLELIPGSATASERIRHQRSYSVPKRFGEAERSSDVPRSATLDRIHHHQSNISKLRSLSSSSSRDNVVSTDPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEKNSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSPSSPQSNSSSVDVRRVWDTPSKALPGKTLDFHFDISETPVIGRRYDELHGSPRQDGKNQGVVTVTRSTSSTSSGSYQSNHVLVPVSWKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSEDGTRDTENMDDTTSEQQFRVFRDFDFLDVELEDGEGETVDSFNWGARRRSIDSLDQTEAQPLEEDSQLSGSSPSLCPIIHDDSDESSEEESLTASQILSASQLNVSLSPTEDLNPMDSPPVSFDNTQADQIPLSTSTPSFEIPLPEGSNHRAEDSAEEEEGIVNENDISLCICESPPAFSCSDILTLETPQREENFFTDEMSCVPSGFGEQFSSVAQAEEEKEELLLESRSSPPPSPFFSAILAAFQPTMCDDAEEAWRSHLNQLVADSDGSCAVYTFQVFSSLFQNIQSKFCTLTCDAAGYLGDGLRGIGAKFLRSSQMLTSCSECPTLFVDADTIVSYGLLEKMKFSVLELQEYLETYNNKKEAVISWLCNCKASFPKCSEDGVITYQPAETEEKQLELCQRLYKLHFQLLLLFQSYCKLIGQVHTINSVPELQNMSRELSDLRSNLRAAAASVAEENTGDRRDSSAESSFSSSEAAVQAILESLKNCDLSRAIRYIRECRKMWPSDIFGSSSENEIQTLLNIYFRHQTLGQTGTFALVGSKQDLSEICNRLTELNCEIRDMIRRAQGYRAITAFLPDSSVTGISL", "length": 3021, "header": "tr|A0A8M2B457-1|A0A8M9NYQ0_DANRE Computationally mapped isoform of Protein furry homolog isoform X1 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} }, { "isoform_ac": "A0A8M3ASX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0A8M3ASX5-1", "sequence": { "sequence": "MASQQDSGFFEISIKSLLKSWSSTSPGYTKPPVPPVCCSQGEKGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKSDIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVILRASSPDLPSSGKLTLNRKSTSQLELIPGSATASERIRHQRSYSVPKRFGEAERSSDVPRSATLDRIHHHQSNISKLRSLSSSSSRDNVVSTDPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEKNSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSPSSPQSNSSSVDVRRVWDTPSKALPGKTLDFHFDISETPVIGRRYDELHGSPRQDGKNQGVVTVTRSTSSTSSGSYQSNHVLVPVSWKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSEDGTRDTENMDDTTSEQQFRVFRDFDFLDVELEDGEGETVDSFNWGARRRSIDSLDQTEAQPLEEDSQLSGSSPSLCPIIHDDSDESSEEESLTASQILSASQLNVSLSPTEDLNPMDSPPVSFDNTQADQIPLSTSTPSFEIPLPEGSNHRAEDSAEEEEGIVNENDISLCICESPPAFSCSDILTLETPQREENFFTDEMSCVPSGFGEQFSSVAQAEEEKEELLLESRSSPPPSPFFSAILAAFQPTMCDDAEEAWRSHLNQLVADSDGSCAVYTFQVFSSLFQNIQSKFCTLTCDAAGYLGDGLRGIGAKFLRSSQMLTSCSECPTLFVDADTIVSYGLLEKMKFSVLELQEYLETYNNKKEAVISWLCNCKASFPKCSEDGVITYQPAETEEKQMEYLAQLELCQRLYKLHFQLLLLFQSYCKLIGQVHTINSVPELQNMSRELSDLRSNLRAAAASVAEENTGDRRDSSAESSFSSSEAAVQAILESLKNCDLSRAIRYIRECRKMWPSDIFGSSSENEIQTLLNIYFRHQTLGQTGTFALVGSKQDLSEICNRLTELNCEIRDMIRRAQGYRAITAFLPDSSVTGISL", "length": 3027, "header": "tr|A0A8M3ASX5-1|A0A8M9NYQ0_DANRE Computationally mapped isoform of Protein furry homolog isoform X1 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} }, { "isoform_ac": "A0A8M9NYQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0A8M9NYQ0-1", "sequence": { "sequence": "MEIQSYSERSYSELNEENDGIEVVSMASVPEDLMLSGDFRGKFKKIRYRKRASILSSSPGYTKPPVPPVCCSQGEKGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKSDIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVILRASSPDLPSSGKLTLNRKSTSQLELIPGSATASERIRHQRSYSVPKRFGEAERSSDVPRSATLDRIHHHQSNISKLRSLSSSSSRDNVVSTDPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEKNSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSPSSPQSNSSSVDVRRVWDTPSKALPGKTLDFHFDISETPVIGRRYDELHGSPRQDGKNQGVVTVTRSTSSTSSGSYQSNHVLVPVSWKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSEDGTRDTENMDDTTSEQQFRVFRDFDFLDVELEDGEGETVDSFNWGARRRSIDSLDQTEAQPLEEDSQLSGSSPSLCPIIHDDSDESSEEESLTASQILSASQLNVSLSPTEDLNPMDSPPVSFDNTQADQIPLSTSTPSFEIPLPEGSNHRAEDSAEEEEGIVNENDISLCICESPPAFSCSDILTLETPQREENFFTDEMSCVPSGFGEQFSSVAQAEEEKEELLLESRSSPPPSPFFSAILAAFQPTMCDDAEEAWRSHLNQLVADSDGSCAVYTFQVFSSLFQNIQSKFCTLTCDAAGYLGDGLRGIGAKFLRSSQMLTSCSECPTLFVDADTIVSYGLLEKMKFSVLELQEYLETYNNKKEAVISWLCNCKASFPKCSEDGVITYQPAETEEKQMEYLAQLELCQRLYKLHFQLLLLFQSYCKLIGQVHTINSVPELQNMSRELSDLRSNLRAAAASVAEENTGDRRDSSAESSFSSSEAAVQAILESLKNCDLSRAIRYIRECRKMWPSDIFGSSSENEIQTLLNIYFRHQTLGQTGTFALVGSKQDLSEICNRLTELNCEIRDMIRRAQGYRAITAFLPDSSVTGISL", "length": 3060, "header": "tr|A0A8M9NYQ0-1|A0A8M9NYQ0_DANRE Isoform 1 of Protein furry homolog isoform X1 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} }, { "isoform_ac": "A0AB32T1Y0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0AB32T1Y0-1", "sequence": { "sequence": "MEIQSYSERSYSELNEENDGIEVVSMASVPEDLMLSGDFRGKFKKIRYRKRASILSSSPGYTKPPVPPVCCSQGEKGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKSDIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVILRASSPDLPSSGKLTLNRKSTSQLELIPGSATASERIRHQRSYSVPKRFGEAERSSDVPRSATLDRIHHHQSNISKLRSLSSSSSRDNVVSTDPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEKNSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSPSSPQSNSSSVDVRRVWDTPSKALPGKTLDFHFDISETPVIGRRYDELHGSPRQDGKNQGVVTVTRSTSSTSSGSYQSNHVLVPVSWKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSEDGTRDTENMDDTTSEQQFRVFRDFDFLDVELEDGEGETVDSFNWGARRRSIDSLDQTEAQPLEEDSQLSGSSPSLCPIIHDDSDESSEEESLTASQILSASQLNVSLSPTEDLNPMDSPPVSFDNTQADQIPLSTSTPSFEIPLPEGSNHRAEDSAEEEEGIVNENDISLCICESPPAFSCSDILTLETPQREENFFTDEMSCVPSGFGEQFSSVAQAEEEKEELLLESRSSPPPSPFFSAILAAFQPTMCDDAEEAWRSHLNQLVADSDGSCAVYTFQVFSSLFQNIQSKFCTLTCDAAGYLGDGLRGIGAKFLRSSQMLTSCSECPTLFVDADTIVSYGLLEKMKFSVLELQEYLETYNNKKEAVISWLCNCKASFPKCSEDGVITYQPAETEEKQLELCQRLYKLHFQLLLLFQSYCKLIGQVHTINSVPELQNMSRELSDLRSNLRAAAASVAEENTGDRRDSSAESSFSSSEAAVQAILESLKNCDLSRAIRYIRECRKMWPSDIFGSSSENEIQTLLNIYFRHQTLGQTGTFALVGSKQDLSEICNRLTELNCEIRDMIRRAQGYRAITAFLPDSSVTGISL", "length": 3054, "header": "tr|A0AB32T1Y0-1|A0A8M9NYQ0_DANRE Computationally mapped isoform of Protein furry homolog isoform X1 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} }, { "isoform_ac": "A0AB32T373-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0AB32T373-1", "sequence": { "sequence": "MEIQSYSERSYSELNEENDGIEVVSMASVPEDLMLSGDFRGKFKKIRYRKRASILSSSPGYTKPPVPPVCCSQGEKGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKSDIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVILRASSPDLPSSGKLTLNRKSTSQLELIPGSATASERIRHQRSYSVPKRFGEAERSSDVPRSATLDRIHHHQSNISKLRSLSSSSSRDNVVSTDPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEKNSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSPSSPQSNSSSVDVRRVWDTPSKALPGKTLDFHFDISETPVIGRRYDELHGSPRQDGKNQGVVTVTRSTSSTSSGSYQSNHVLVPVSWKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSEDGTRDTENMDDTTSEQQFRVFRDFDFLDVELEDGEELQVSSGILQFCAVCNRTKMCLFTFCGVMHVHNSGKNFLSNLKTH", "length": 2546, "header": "tr|A0AB32T373-1|A0A8M9NYQ0_DANRE Computationally mapped isoform of Protein furry homolog isoform X1 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} }, { "isoform_ac": "A0AB32T4M2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0AB32T4M2-1", "sequence": { "sequence": "MDNTVMCWNKTSMVNFIKGLASPGYTKPPVPPVCCSQGEKGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKSDIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVILRASSPDLPSSGKLTLNRKSTSQLELIPGSATASERIRHQRSYSVPKRFGEAERSSDVPRSATLDRIHHHQSNISKLRSLSSSSSRDNVVSTDPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEKNSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSPSSPQSNSSSVDVRRVWDTPSKALPGKTLDFHFDISETPVIGRRYDELHGSPRQDGKNQGVVTVTRSTSSTSSGSYQSNHVLVPVSWKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSEDGTRDTENMDDTTSEQQFRVFRDFDFLDVELEDGEGETVDSFNWGARRRSIDSLDQTEAQPLEEDSQLSGSSPSLCPIIHDDSDESSEEESLTASQILSASQLNVSLSPTEDLNPMDSPPVSFDNTQADQIPLSTSTPSFEIPLPEGSNHRAEDSAEEEEGIVNENDISLCICESPPAFSCSDILTLETPQREENFFTDEMSCVPSGFGEQFSSVAQAEEEKEELLLESRSSPPPSPFFSAILAAFQPTMCDDAEEAWRSHLNQLVADSDGSCAVYTFQVFSSLFQNIQSKFCTLTCDAAGYLGDGLRGIGAKFLRSSQMLTSCSECPTLFVDADTIVSYGLLEKMKFSVLELQEYLETYNNKKEAVISWLCNCKASFPKCSEDGVITYQPAETEEKQMEYLAQLELCQRLYKLHFQLLLLFQSYCKLIGQVHTINSVPELQNMSRELSDLRSNLRAAAASVAEENTGDRRDSSAESSFSSSEAAVQAILESLKNCDLSRAIRYIRECRKMWPSDIFGSSSENEIQTLLNIYFRHQTLGQTGTFALVGSKQDLSEICNRLTELNCEIRDMIRRAQGYRAITAFLPDSSVTGISL", "length": 3024, "header": "tr|A0AB32T4M2-1|A0A8M9NYQ0_DANRE Computationally mapped isoform of Protein furry homolog isoform X1 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} }, { "isoform_ac": "A0AB32T7K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0AB32T7K2-1", "sequence": { "sequence": "MMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKSDIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVILRASSPDLPSSGKLTLNRKSTSQLELIPGSATASERIRHQRSYSVPKRFGEAERSSDVPRSATLDRIHHHQSNISKLRSLSSSSSRDNVVSTDPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEKNSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSPSSPQSNSSSVDVRRVWDTPSKALPGKTLDFHFDISETPVIGRRYDELHGSPRQDGKNQGVVTVTRSTSSTSSGSYQSNHVLVPVSWKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSEDGTRDTENMDDTTSEQQFRVFRDFDFLDVELEDGEGETVDSFNWGARRRSIDSLDQTEAQPLEEDSQLSGSSPSLCPIIHDDSDESSEEESLTASQILSASQLNVSLSPTEDLNPMDSPPVSFDNTQADQIPLSTSTPSFEIPLPEGSNHRAEDSAEEEEGIVNENDISLCICESPPAFSCSDILTLETPQREENFFTDEMSCVPSGFGEQFSSVAQAEEEKEELLLESRSSPPPSPFFSAILAAFQPTMCDDAEEAWRSHLNQLVADSDGSCAVYTFQVFSSLFQNIQSKFCTLTCDAAGYLGDGLRGIGAKFLRSSQMLTSCSECPTLFVDADTIVSYGLLEKMKFSVLELQEYLETYNNKKEAVISWLCNCKASFPKCSEDGVITYQPAETEEKQMEYLAQLELCQRLYKLHFQLLLLFQSYCKLIGQVHTINSVPELQNMSRELSDLRSNLRAAAASVAEENTGDRRDSSAESSFSSSEAAVQAILESLKNCDLSRAIRYIRECRKMWPSDIFGSSSENEIQTLLNIYFRHQTLGQTGTFALVGSKQDLSEICNRLTELNCEIRDMIRRAQGYRAITAFLPDSSVTGISL", "length": 2980, "header": "tr|A0AB32T7K2-1|A0A8M9NYQ0_DANRE Computationally mapped isoform of Protein furry homolog isoform X1 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} }, { "isoform_ac": "A0AC58HD34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0AC58HD34-1", "sequence": { "sequence": "MDNTVMCWNKTSMVNFIKGLASPGYTKPPVPPVCCSQGEKGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKSDIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVILRASSPDLPSSGKLTLNRKSTSQLELIPGSATASERIRHQRSYSVPKRFGEAERSSDVPRSATLDRIHHHQSNISKLRSLSSSSSRDNVVSTDPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEKNSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSPSSPQSNSSSVDVRRVWDTPSKALPGKTLDFHFDISETPVIGRRYDELHGSPRQDGKNQGVVTVTRSTSSTSSGSYQSNHVLVPVSWKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSEDGTRDTENMDDTTSEQQFRVFRDFDFLDVELEDGEGETVDSFNWGARRRSIDSLDQTEAQPLEEDSQLSGSSPSLCPIIHDDSDESSEEESLTASQILSASQLNVSLSPTEDLNPMDSPPVSFDNTQADQIPLSTSTPSFEIPLPEGSNHRAEDSAEEEEGIVNENDISLCICESPPAFSCSDILTLETPQREENFFTDEMSCVPSGFGEQFSSVAQAEEEKEELLLESRSSPPPSPFFSAILAAFQPTMCDDAEEAWRSHLNQLVADSDGSCAVYTFQVFSSLFQNIQSKFCTLTCDAAGYLGDGLRGIGAKFLRSSQMLTSCSECPTLFVDADTIVSYGLLEKMKFSVLELQEYLETYNNKKEAVISWLCNCKASFPKCSEDGVITYQPAETEEKQLELCQRLYKLHFQLLLLFQSYCKLIGQVHTINSVPELQNMSRELSDLRSNLRAAAASVAEENTGDRRDSSAESSFSSSEAAVQAILESLKNCDLSRAIRYIRECRKMWPSDIFGSSSENEIQTLLNIYFRHQTLGQTGTFALVGSKQDLSEICNRLTELNCEIRDMIRRAQGYRAITAFLPDSSVTGISL", "length": 3018, "header": "tr|A0AC58HD34-1|A0AC58HD34_DANRE Computationally mapped isoform of Protein furry homolog isoform X6 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} }, { "isoform_ac": "A0AC58HD35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0AC58HD35-1", "sequence": { "sequence": "MMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKSDIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVILRASSPDLPSSGKLTLNRKSTSQLELIPGSATASERIRHQRSYSVPKRFGEAERSSDVPRSATLDRIHHHQSNISKLRSLSSSSSRDNVVSTDPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEKNSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSPSSPQSNSSSVDVRRVWDTPSKALPGKTLDFHFDISETPVIGRRYDELHGSPRQDGKNQGVVTVTRSTSSTSSGSYQSNHVLVPVSWKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSEDGTRDTENMDDTTSEQQFRVFRDFDFLDVELEDGEGETVDSFNWGARRRSIDSLDQTEAQPLEEDSQLSGSSPSLCPIIHDDSDESSEEESLTASQILSASQLNVSLSPTEDLNPMDSPPVSFDNTQADQIPLSTSTPSFEIPLPEGSNHRAEDSAEEEEGIVNENDISLCICESPPAFSCSDILTLETPQREENFFTDEMSCVPSGFGEQFSSVAQAEEEKEELLLESRSSPPPSPFFSAILAAFQPTMCDDAEEAWRSHLNQLVADSDGSCAVYTFQVFSSLFQNIQSKFCTLTCDAAGYLGDGLRGIGAKFLRSSQMLTSCSECPTLFVDADTIVSYGLLEKMKFSVLELQEYLETYNNKKEAVISWLCNCKASFPKCSEDGVITYQPAETEEKQLELCQRLYKLHFQLLLLFQSYCKLIGQVHTINSVPELQNMSRELSDLRSNLRAAAASVAEENTGDRRDSSAESSFSSSEAAVQAILESLKNCDLSRAIRYIRECRKMWPSDIFGSSSENEIQTLLNIYFRHQTLGQTGTFALVGSKQDLSEICNRLTELNCEIRDMIRRAQGYRAITAFLPDSSVTGISL", "length": 2974, "header": "tr|A0AC58HD35-1|A0AC58HD35_DANRE Computationally mapped isoform of Protein furry homolog isoform X8 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} }, { "isoform_ac": "A0AC58HD43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0AC58HD43-1", "sequence": { "sequence": "MEIQSYSERSYSELNEENDGIEVVSMASVPEDLMLSGDFRGKFKKIRYRKRASILSSSPGYTKPPVPPVCCSQGEKGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRAVQELIQEMTHLTHLASDLTQDITDLYVVFHQSSSQYFSMLCGF", "length": 1875, "header": "tr|A0AC58HD43-1|A0AC58HD43_DANRE Computationally mapped isoform of Protein furry homolog isoform X11 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} }, { "isoform_ac": "A0AC58HD44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0AC58HD44-1", "sequence": { "sequence": "MDNTVMCWNKTSMVNFIKGLASPGYTKPPVPPVCCSQGEKGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRAVQELIQEMTHLTHLASDLTQDITDLYVVFHQSSSQYFSMLCGF", "length": 1839, "header": "tr|A0AC58HD44-1|A0AC58HD44_DANRE Computationally mapped isoform of Protein furry homolog isoform X12 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} }, { "isoform_ac": "A0AC58HD68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0AC58HD68-1", "sequence": { "sequence": "MDNTVMCWNKTSMVNFIKGLASPGYTKPPVPPVCCSQGEKGPPAMMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRPFGPLWSHEDITPKNPQSKSTEQLTNFLRHVVSVFKESKSDIRLEQQLSEVALQMALCSSSRHYAGRSFQVFRALRQPLSALAVSDLLSRLVEVVGEHGEEVQGYVMELLLTLESVVDNLAECLKNNDFFVILRASSPDLPSSGKLTLNRKSTSQLELIPGSATASERIRHQRSYSVPKRFGEAERSSDVPRSATLDRIHHHQSNISKLRSLSSSSSRDNVVSTDPTNANHPHNLLATIFWAVVSLMESDFEFEYQMSLRLLGKLLGHISLDKQEYKEKLEKIQLQLKWKDFTGLQKLLLKGFTSANTTELTLELFSQLTPVSRLPVVDTSQAIGFPLNVLCLIPHLVLHFDSPSQFCKDVAERISQICLEEKNSKLSNLAHVMTLYKTHSYTRDCFSWVNVVCRYLHEAFSDSTLSMVTYMTELLEKGLPSMQQTLLQIIYSLLSHMDLSGIQAKLFNMEVLTTIEKFVQTTHWKEALNILKLVVSRSASLVSPSSPQSNSSSVDVRRVWDTPSKALPGKTLDFHFDISETPVIGRRYDELHGSPRQDGKNQGVVTVTRSTSSTSSGSYQSNHVLVPVSWKRPQSSQKRTREKLVNVLTLCGQEVGLTKNPSVIFSSCGELELIEHQPSLVSSEDGTRDTENMDDTTSEQQFRVFRDFDFLDVELEDGEELQVSSGILQFCAVCNRTKMCLFTFCGVMHVHNSGKNFLSNLKTH", "length": 2510, "header": "tr|A0AC58HD68-1|A0AC58HD68_DANRE Computationally mapped isoform of Protein furry homolog isoform X10 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} }, { "isoform_ac": "A0AC58HD70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0/entry#A0AC58HD70-1", "sequence": { "sequence": "MMPISVDPESRPGEYVLKSLFANFTTISERKIRIVMAEPLEKPLVKSLQRGEDLQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGVDDESHEYRPRSNTKSKNDEQQKDYLLERRDLAIDFIFSLVLIEVLKQMPLHPVVDGLVQEVIHLAFKHFKYKEGYHGPNTANMHIVADLYAEVIGVLSQAKFPAVKKRFTSELKELRQKEQSPYVVQSTISLIMGVKFFRVKMYPVEEFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLDLSSRKKHSLALYPMVTCLLCVSQKQFFLNRWHVFLNNCLSNLKSKDPKMARVALESLYRLLWVYMIRIKCESNTATQGRLNSIVTNLFPKGSRSVVPKDMPLNIFVKIIQFIAQERLDFAMKEVIFDLLFVGKPAKAFSLNPERMNIGLRAFLVIADKLQQKDGEPPMPNTGATLPSGNTLRVKKTFLSKPLSEDEAKVIGMSLYYPHVRKALDNILRHLDKEVGRCMMLSNAQMLNKEPEDMITGERKPKIDLFRTCMAAIPRILPDGMSKSELIDLLARLTIHMDDELRLIAQNSLQSLLVDFSDWREEVLLGFCSFLLREVQDTHQTLLDSSLKLLLQLLTQWKLALLSTNKSPDTSKICSAELLQSSSGSRLPAEWTSHSTVLHAVEGLALVLLCSCQTGTRRLAVSILREVRQIFIIIGQTEEDERPMIDVLDQLSPMVLESFAHVAVADSASLPAGQHADLQWLVEWNGSLVGSHYDVRSPSRVWILAQSLKEPWALCLFSLLRQEYLPKHCPTALSYAWPYAFTRLQLLMPLLEPSNPVNAKKTSSAGSADTYVSLWRNYLILCFGVAKPSIMSPGHLRASTPEIITPSPDSNSSYDNKILGTPSVAWLLKQLVPLMRSESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAESDKDMEILKDIRAHFSAMVANLIQSVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSSVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQMNLFNWAVDRCYTGSCQLASGCFKAIATVCGSRNYSSDIVTLLNLVLFKASDTNREIYEIAMQLMQILEAKLSVYSKRIVEQKSGAILYGTHRPLPPLYSLSVTQLSKQLARMYPELTLPLFSEVSQRFPTTHPNGRQVMLAYLLPWLSNIELVDGGLLSTVSGPSSCVDNRKGYTHNSSSPHLLRGTGWGSLQASSLVLNNLMFMTAKYGDDVPGAEMENAWNALVSNERWTNNLRTVLQFLISLCGVSSDTSLLPHIKKVVIYLCRNNTMQTMEELLYELQQTDPVNPVVVHCDNPPFYRFSATSKIVTTSSGPPSSSKTLVCCQENIPDADDSPITKECDDRLSNILRAHNRLESRYSSSSGGSYDEEKSEPIPPYAMWLMSVLETNQPLPLPMPVNGGCWAPLVDYLPETVTPRGPLHRSNIAVMFMTELVVDHSVKEDWALHLPLLLHACFLGMDHFRPEVFEHCKRLLLHLLITLSCNNNFSLIASVLLNTRDANSNKSLTFKPFYQPDFYTGGVDFLRNGQASPVPDSGLSSSSTSSSLSLGGSSSNLPHLTQEEMENMESSTEDDEKSSKLIEFLTTRAVQELIQEMTHLTHLASDLTQDITDLYVVFHQSSSQYFSMLCGF", "length": 1795, "header": "tr|A0AC58HD70-1|A0AC58HD70_DANRE Computationally mapped isoform of Protein furry homolog isoform X13 OS=Danio rerio OX=7955 GN=frya PE=4 SV=1 CANONICAL=A0A8M9NYQ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:566822", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566822", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G1L6-1", "protein_name": "FRY microtubule binding protein", "gene_name": "Fry", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQQDSGFFEISIKYLLKSWSNASPVGNGYIKPPVPPASGTHREKGPPAMLPINVDPDSKPGEYVLKSVFVSFTTQAERKIRIIMAEPLEKPLTKSLQRGEDPQFDQVISSMSSLSEYCLPSILRTLFDWYKRQNGMEDESHEYRPRTSNKSKSDEQQRDYLMERRDLAIDFIFSLVLIEVLKQIPLHPVIDGLVHDIINLAFKHFKYKEGYLGPNTGNMHIVADLYAEVIGVLAQAKFPAVKKKFMAELKELRQKEQSPYVVQSIISLIMGVKFFRIKMYPVEDFEASLQFMQECAHYFLEVKDKDIKHALAGLFVEILVPVAATVKNEVNVPCLRNFVESLYDTTLELSSRKKHSLALYPLVTCLLCVSQKQLFLNRWHVFLNNCLSNLKNKDPKMARVALESLYRLLWVYMIRIKCESNTATQSRLITITTTLFPKGSRGVVPRDMPLNIFVKIIQFIAQERLDFAMKEIIFDFLCVGKPAKAFSLNPERMNIGLRAFLVIADSLQQKDGEPPMPVTGAVLPSGNTLRVKKTYLSKTLTEEEAKMIGMSLYYSQVRKAVGNILRHLDKEVGRCMMLTNVQMLNKEPEDMITGERKPKIDLFRTCVAAIPRLLPDGVSKVELIDLLARLSIHMDDELRHIAQNSLQGLLVDFSDWREEVLFGFTNFLLREVNDVHHTLLDSSLKLLLQLLTQWKLVIQTQGRVYEQAKIRNSELIPNGSGHRMQSERGPHCSVLHAVEGFALVLLCSFQMATRKLSVLILKEIRALFLALGQPEDDDRPMIDVMDQLSSSILESFIHVAVSDSATLPPTHNVDLQWLVEWNAVLVNSHYDVKSPSHVWIFAQSVKDPWVLCLFSFLRQENLPKHCPTALSYAWPYAFTRLQSVMPLVDPNSPVNAKKTSTASSGDNYVTLWRNYLILCFGVAKPSIMSPGHLRASTPEIMATTPDGTVSYDNKAIGTPSVGVLLKQLVPLMRLESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADASVISDSTNGALERDTLALGALFLEYVDLTRMLLEAENDKEVEILKDIRAHFSAMVANLIQCVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVMLLLELNPDQINLFNWAIDRCYTGSYQLASGCFKAIATVCGNRNYPFDIVTLLNLVLFKASDTNREIYEVSMQLMQILKAKLFLHSKKAAEQRPGSVLYGTHGPLPPLYSVSLALLSRELARMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLHNIELVDSRLLLPGSSPSSPEDEVKDREGEVTASHGLKGKGWGSPEATSLVLNNLMYMTAKYGDEVPGAEMENAWNALANNEKWSNNLRVTLQFLISLCGVSSDTILLPYIKKVAIYLCRNNTIQTMEELLFELQQTEPVNPIVQHCDNPPFYRFTASSKATAAASGTTSSSNTVVAGQDSFPDPEESKILKESDDRFSNVIRAHTRLESRYSNSSGGSYDEDKNDPISPYTGWLLSITEAKQPQPLPMPCTGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLHAVFLGLDHYRPEVFEHSKKLLLHLLIALSCNSNFHAIASVLLQTREMGEVKTLTMQPAYQPEYLYTGGFDFLREDQSSPVPDSGLSSSSTSSSISLGGSSGNLPQMTQEVEDVDAAAESDEKANKLIEFLTTRAFGPLWCHEDITPKNQNSKSAEQLSNFLRHVVSVFKDSKSGLHLEQHLSEVALQTALASSSRHYAGRSFQIFRALKQPLSAHALSDLLSRLVEVIGEHGDEIQGYVMEALLTLEAAVDNLSDCLKNSDLFTVLSRSSSPDLSSSSKLTASRKSTGQLNVSPGTPSGSTATAERSRHQRSFSVPKKFGVVDRSSDPPRSATLDRIQACTQQGLSSKTRSSSSLKESLTDPSHVNHPTNLLATIFWVTVALMESDFEFEYLMALRLLNRLLAQMPLEKAENREKLEKLQAQLKWADFPGLQQLLLKGFTSLTTTDLTLQLFSLLTPVSRVPMVDSSQAIGFPLNVLCLLPQLIQHFENPNQFCKGIAERIAQVCLEEKNPKLSNLAHVMTLYKTHSYTRDCATWVNVVCRYLHEAYADITLNMVTYLAELLEKGLPSMQQPLLQVIYCLLSYMDLSVVPGKQFNMEVLKTIEKYVQSIHWREALNILKLVVSRSASLVLPSYQHSDLSKIELHRVWTSASKELPGKTLDFHFDISETPIIGRRYDELQNSSGRDGKPRAMAVTRSASSTSSGSNSNVLVPVSWKRPQYSQKRTKEKLVHVLSLCGQEVGLSKNPSVIFSSCGDLDLPEHQTSLVSSEDGTREQENMDDANSEQQFRVFRDFDFLDVELEDGEGESMDNFNWGVRRRSLDSLDKCDMQTLEERQLSRSTPSLNKMSHEDSDESSEEDLTASQILEHSDLIMNLSPSEEANPMELLTSACDSTPADPHPFNARITNFEASLPDINNLQISEGSKAEVVPEEEDTTVHEDDLSSSINELPATFECSDSFSLDMTEAEEKGNRGLDQYTLASFGEGDRGVSPPPSPFFSAILAAFQPVSCDDAEEAWRSHINQLMCDSDGSCAVYTFHVFSSLFKNIQKRFCFLTCDAASYLGDNLRGIGSKFVSSSQMLTSCSECPTLFVDAETLLSCGLLDKLKFSVLELQEYLDTYNNRKEATLSWLANCKATFAGSSRDEVITCQPGDSEEKQLELCQRLYKLHFQLLLLYQSYCKLIGQVHEVSSVPELLNMSRELSDLKRKLKEATAAISTDPLYIEGAWSEPTFTSTEAAIQSMLECLKNNDLGKALRQIKECRSLWPNDIFGSSSDDEVQTLLNIYFRHQTLGQTGTYALVGSNHSLTEICTKLMELNMEIRDMIRRAQSSRVLTTFLPDSSVSGTSL", "length": 3011 }, "evidence": [ { "id": "RGD:1307034", "url": "https://alliancegenome.org/gene/RGD:1307034#orthology", "database": "AGR" }, { "id": "MGI:2443895", "url": "https://alliancegenome.org/gene/MGI:2443895#orthology", "database": "AGR" }, { "id": "HGNC:20367", "url": "https://alliancegenome.org/gene/HGNC:20367#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060510-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060510-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0016081", "url": "https://alliancegenome.org/gene/FB:FBgn0016081#orthology", "database": "AGR" }, { "id": "SGD:S000001391", "url": "https://alliancegenome.org/gene/SGD:S000001391#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AB32TIX3-1", "protein_name": "Protein furry homolog isoform X1", "gene_name": "fryb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVKDVGSAGVVVDSKLDPCETQSRDGIVLVQMASLSMHMFAPADFKGKFRKIQPRKRPTIIKEASPIGKRPLPQVSSALGERKGPVATMPVTVDPESKPGEYVLKSLFANFTTLSERKIRIIMAEPLEKPLTKSLQRGEDPQFDQLISTMSSLAEYCLPSILRTLFDWYKRQNGLEDESHEYRPRANTKSKNDEQQKDYLMERRDLAIDFIFSLVLIEVLKQIPLHPLLDGLIQEVINLAFKHFKYKEGYLGPNTTNMHIVADLYAEVVGVVAQSRFPAVRKKFISELKELRQKEQSPYVVQSTISLIMGVKFFRIKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHSLAGLFVEILVPVAATVKNEVNVPCLRNFVETLYDTTLDLSSRKKHSQALYPLVTCLLCVSQKQIFLNRWHVFLNNCLSNLKNKDHKMARVALESLYRLLWVYMIRIKCESNTATQSRLTSIISTLFPKGSRSVVPRDMPLNIFVKIIQFIAQERLDFAMKEIICDLLSVGKSAKAFSLNPERMNIALRAFLVIADNLQQKDGEPPMPNTGATLPSGNTLKKKKTYLSKTLTEEEAKLIGMALYYSQVRKAMDNILRHLDKEVGRCMMLTNAQMLNKEPEDMITGERKPKIDLFRTCVAAIPRILPDGLSKIELIDLLARLTVHMDDELRLIAQNSLQSLLLDFSDWREDVLFGYTNFLLREVQDTQQGLQDSSVKLLLHFLTQWRLAIQAPGKRSAEMGSQSSGSSRLAPDRSPHSTVLHAVEGLALLLLCSCQTSTRKLAVSVLREIRLLFTAIGQAEDDDKSMIEVMDQLAPSVLDSFVHVAVSDSATLPLSHHVDLQWLVEWNARLVNSHYDVKSPSHVWIFAQSVKDPWVLCLYSFLRPEHLPKHCPTALSYAWPYAFTRLQLLMPLVDPNSPVYAKKTSTPGSADGYVTLWRNYLIMCLGVAKPSIMSPGHLRASTPEIMATTPDGSVTYDNKVIGTPSVAWLLKQLVPLMRSESLEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADSGVISDSTNGALERDSLALGALFLEYVDLTRMLLEAENDKELDILKDMRAHFSGMVANLIQCVPVHNRRLLFPQQSLRHHLFILFSQWAGPFSVMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSTDGYLYKWLDNILACHDLRVHRLGCEVVILLLELNPDQVNLFNWAVDRCFTGSYQLASGCFKAIATVCGSRNYPCDIVTLLNLVLFKSSDTSREIYEISMQLMQVLESKLSVYSKRTVGQKSGSILYGTHGPLPPLYSVSLFQLSNQLACMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLNNIELVDTGLLPPASSPCTPEEEAREQADNLGITHRLKGNGWGSLQATSLVLNNLMFMTAKYGDEVPGPEMENAWNALVSNDKWSNNLRITLQFLISLCGVSSDTTLLPYIKKVVIYLCRNNTIQTMEELLFELQQTDPVNPVVLHCDNPPFYRFAASNKTSVVASGTTSSSNTVVAGQENFQDTDEAKITRETEERLSSAARAHNRLESRYSNSSGGSYDEEKNDPLPPYAAWLISVLESNRPQSLPMPVNGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLHALFLGLDHYRPEVFEHSKRLLLHLLIALSCNNNFQVIASVLLLTREIGDNKTLTVKSSYQPEYVYTGGFDFLREWQASPVADSGLSSSSTSSSVSLGGSIGNLPQITADLEELDESSTESEEKTNKLIEFLTTSAWSTVLSLLRAFGPLWCHEDITPKNLNSKSAEQLTNFLRHVVSVFKESKSDFHLEHQLSDVALQTALCSSSRHYAGRSFQIFRALRQPLSAHAVSDLLSRLVEVVGEHGDEVQGYVMEILLTLESVVDNLAECLNNSELMAALTRDSSPDFLVSGKLNLNRKSTGQINLLQEAGTNERNRHQRSYSVPKKFGESGENSSSNPPRSATLDRIQACTQQGLMRSARSTSSNSTRADTSVITDPSHSSHPVNLLATIFWVAVSLMESDFEFEYQMSLRLVHKLLARVPLDLQENRERLEKLQAQLRWSGFSGLQQLLLKGFTSPTTNDLTLQLFCQLTPVSRVPVVDTSQAIGFPLNVLCLLPHLVQHFGSPTQFCKESAERIAQVCLEEKDKNAKLSNLAHVMTLYKTRSYTRDPFSWVNVVCRYLHEAFSDITLSLVTYMAELLDKGLPSMQQPLLQIIYSLLSHMDLAGIQVKPFNVEVLKTIEKFVQTVHWKEALNILKLVVSRSASLSLPSYTHGDLAHLEVSRMMWDGSSKALPGKTMEFHFDISETPVIGRRYDDLQGSGGRDGKARAIAVTRSTSSTSSGSNSNTVLVPVSWKRPQSSQKRTREKLVNVLSLCGQEVGLTKNPSVIFSSCGDLDLMEHQPSQVSSEDGTREDTLDDTTSEQQFRVFRDFDFLDVELEDGEGESMDNFNWGVRRRSLDSTDLTELLEESQHSDITPCIGIGIGIGLHDPQRDSDDSSEEESNSTSQSLSHSQLTMNLSPSEDTNHTDSLSTSYDTTSADPNSLNAATPCLGTSLPDDHIIPPVLPEDEESNIQEDDMPFGVNDLPMRFDCGSSTNLDLPAELNRAGINQNPNSLPSYHFGEDRDDLDELGFPPPPSPFFSAILAAFQPAVCDDSEEAWRSHVNQLMCDTDGSSAVYTFHIFSAMFQNMQNKFCSLTSDASTYLGEGLRGIGSKFVQSSDMLALCSDCPMLYVDAETIVSYGLLEKMKFSVLELQEYLDTYNTREEAVVSWLQNCKATFPRFPDDGVITCQPGDSEEKQMETLAQLELCQRLYKLHFQLLLLFQSYCKLIGQVNTISSVPELWNMSRELSDLKNCLRLAEASLAGDLEDRHRHGSQSIFSSSETAVQAILECLNNNDFSMAIRYTQECRRIWPNDIFGGGSEDEIQTLLNVYFRHQTIGQTGTFALVGSNKDMSEVCTKIMELNGEVRDMIRRAQGYQVISSSLVDSSVSGVSL", "length": 3071 }, "evidence": [ { "id": "RGD:1307034", "url": "https://alliancegenome.org/gene/RGD:1307034#orthology", "database": "AGR" }, { "id": "MGI:2443895", "url": "https://alliancegenome.org/gene/MGI:2443895#orthology", "database": "AGR" }, { "id": "HGNC:20367", "url": "https://alliancegenome.org/gene/HGNC:20367#orthology", "database": "AGR" }, { "id": "FB:FBgn0016081", "url": "https://alliancegenome.org/gene/FB:FBgn0016081#orthology", "database": "AGR" }, { "id": "SGD:S000001391", "url": "https://alliancegenome.org/gene/SGD:S000001391#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58I3F5-1", "protein_name": "Protein furry homolog-like isoform X1", "gene_name": "fryl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEFLKSLVPTVISGDGGMQAADTAGVCPRETGPRLLRMKRLISSNEEEQDGSSPPSRPVVRLQRHRVKASVPVSNSSVSRRGTSPSAPPSWEKRSLHPATMSSITIDPELKPGEFVIKSLFAEFAVLAEKKIEVVMAEPLEKLLSRSLQRGEDAQFDQLISSMSSIAEHCLPSLLRTLFDWYRRQSGTEDESYEYRPRSSTKSKGDEQHRDKDYLVERRDLAIDFMFCLVSVEVLKQIPLHPVPDTLVQEVLNLAFKHFKHKEGYSGPNTGNVHIIADLYAEVIGVLAQSKFQAVRKKFITELKELRLKEQSPHVVQSIISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTTFDLSSRKKHSLALYPLVTCLLCVSQKQFFLNNWHIFLQNCLSHLKMPSNNSIRKQIETLQNKDPKMSRVALESLYRLLWVYIIRIKCESNTTTQSRLLSIVTALFPKGSRSVVPRDTPLNIFVKIIQFIAQERLDFAMKEIIYDLLCVGKSHKTFTINPERMNIGLRAFLVIADSLQQKDGEPPMPTTGVILPSGNTLRVKKIFLNTTLTDEEAKVIGMSLYYPQVRKALDNILRHLDKEVGRSMSMTNVQMSNKEPEDMITGERKPKIDLFRTCVAAIPRLIPDGMSRQDLIELLAKLTIHMDEELRGLAFTTLQALMVDFPDWREDVLSGFVYFIVREVTDVHPTLLDNAVKMLLQLISQWRQAVQSSNRCHDSQSPSLPLERSPLWTVLHVVEGLALVVLCSCRPATRRLAVNVLKEVRSLHTALGIAKGDEELAIDVMDRLSASVLESFIHLTGADQTSLLYCPSGIDLQTLAEWSSSPISHQFDVVSPSHIWVFAHVTQGQDPWVISLSSYLRQENLPKHCPSALSYAWVFASTRLQLLSPQVDINSPINAKKVNSMSSSSDSYVGLWRNYLILCCSSATSSSSSSSSSSSSAPGSVRCSPPETLASTPDSGYCYDSKIISIPSPSSLFKHVVPMMRSESMDITESLVLGLGRTNPVAFRELLEELNPIIKEALERRPENMKRRRRRDILRVQLVRIFELLADSGVISQTVSGGLDGESHSLNSTLLEYVDLTRQLLEAENDKDSDTLRDIRSHFSALVANIIQNVPVHQRRSIFPQQSLRHSLFMLFSHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNILDSQDRKVHQLGCEAVMLLLELNPDQSNLMFWAVDRCYTGTRRVAAGCFRAIANVFHNRDYQFDTVVLLNLILFKAADSSRDIYEVAMQLLQILEPKLFRYAHKLEIQRTDGVLSPASPLPHLYSVSYYQLSEELARTYPELTLPIFSEVSQRIQTAHPGGRQVMLHYLLPWMNNVELVDFKPSVRRQEEPSSAEEEEDAHERELMMVNSRRWLKGEGWGSPHATTMILNNLMFMTAKLQDACCMENGMSCSAQYGDEFAWSEIENVWTTLADSWPKNLKIILHFLISMSGVNSEPSLLPYVKRVVVYLGRDKTMQLLEELMYELELTDPVSSAVTHMDNPPYYRITSSYKIPSVTSGTASSSNTMVPGPDGHHDSKLKDSNIEDSYTHLDIYTGLNSNLNRQHHRLESRYSSSSGGSYEEEKSDSMPVYANWRLKVMDHNRPEPLPFPPTGGCWSPLVDYLPETTTPGVSLHRCNIAVILLTDLIVDHGVKVEWSAYLHLLLHSIFIGFDHQHPEVYEHCKRLLLHLLVVQGTNSSVQSLASVLLRNRELNEPRVLTVKPTLQEFNLTGVTELMPDYQPSPMTDSGLSSSSTSSSISLGSSALPHLPPTLLNEVDLSAEQDEKVKNLIEFISSRKRGPLWNHEDVSPKNPNIKSADQLSVFLRHVVNVFKQTPSGFQLEQELSEIALQTALSCSSRHYAGRSFQIFRALKQPMTASTLSDMLSRLVETVGDPGEEAQGFVIELLLTLEAGIDTLAETMKSYDLLTAISQASHDPLHGTKFANNRKSTGQLNLGSSFLHAHYSHARSNSLRASLMGERMGDRRRSNTLDIADRLGGSHGNLARTRSLSSLREGGVRGDGGGGTGGGSGEVVPQTDPTNLMATVFWIATSLLESDYEFEYLLALRLLNRLLAQMPLEKADSREKLERVQGKLKWYNFPGLLTLFLKGFTSAATQELTIHLLSKLITVSRHTLIDPSQLAGFPLNILCLLPHLIQHFDNPTGFCKETADRIAKVCAEEKSATLANLAHMMSLYSTHSYSRDSTNWINVVCRYLHDAFAEITFNLVTYLAELLEKGLNSMQQSLLQIIYSLLSHIDLSAAPVKQFNLEIMKIIGKYVQSPYWKEAQNILKLVVSRSASLVVPDEVQRSYSTESTGSPEIAFTRIFNNSSKELPGKTLDFHFDISETPIIGHKYGDQRSAAGRNGKPQVIAVTRSTSSTSSGSNSNGLVPVSWKRPQLSQRRTREKLMNVLSLCGPESGMPKNPSVVFSSNEDLDAGDQQTSLIPTVEEVTREEEAQAEDAGSEQQFGVFKDFDFLDVELEDGEGESMDNFNWGVRRRSLDSIDKGDGDTPSLQDCQYSGSTPSLIQPEDTDESSEEEVLSASQILTRSNLLNSDSATDDAISNHMDSLQQSQESSSSVLTEEATPTPLLHRPDSPAHETARSDSNSSQLPEDASVTAGDELSSSVSEDTGFGSAPPLPSDPPELCDLHDSQDPTDDLDPAPPPPPAMDSPPGSLFDDEPGITPSVIDTTLDSMCEEETVLPLVLNSAPDSVCEDDVTLALKELDDRCEEEEADFYGLSSQDEGDADGFPELQASPPPSPFLSAILAAFQPVAYDDEEDAWRCHVNQMLSDSDGSSAVYTFHVFSRLFQHIQRKFDSITHSSVRFLGEGLQRMGNQFLSSLEVMTSCSQCPTVLLDAETLVSCGLLETLKFSVLELQEHLDTYNSKREAAEQWLDNCRKTFGDKDSNQRPNTQAQQMEMLAELELCRRLYKLHFQLLLLFQAYCKLISRVDTIKREAEVTNMSEELAILESCLKEAESVNDEQDIGEFEVDQSSTETAIHSLIESLRARDFCTAITQVKAFRCLWPNDIFGSDRDDAVQTLLHIYFRHQTLGQTGCLAVVGPSRDLSQASARLMELNLQIREALCQAQTHPHLQSHQTHIQSPTPTGHIQTQIDTQNTVLSTGL", "length": 3216 }, "evidence": [ { "id": "FB:FBgn0016081", "url": "https://alliancegenome.org/gene/FB:FBgn0016081#orthology", "database": "AGR" }, { "id": "SGD:S000001391", "url": "https://alliancegenome.org/gene/SGD:S000001391#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZQY4-1", "protein_name": "FRY like transcription coactivator", "gene_name": "Fryl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGVTNSTFLPSSLRHSTLCYISGVTLLLFPSAPSSVPVKFKPQAGEASRWILSKFGVFSTNAVPHPQSLSASAPVSKVNKFCATSNFHSALGRKSTIMSNITIDPDVKPGEYVIKSLFAEFAVQAEKKIEVVMAEPLEKLLSRSLQRGEDLQFDQLISSMSSVAEHCLPSLLRTLFDWYRRQNGTDDESYGYRPRSSTKSKGDEQHRERDYLLERRDLAVDFIFCLVLVEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSGTNTGNVHIIADLYAEVIGVLAQSKFQAVRKKFVTELKELRQKEQSPHVVQSIISLIMGMKFFRVMMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTTFELSSRKKHSLALYPLITCLLCVSQKQFFLNNWHIFLQNCLSHLKMPSNNSIRKQIETLQNKDPKMSRVALESLYRLLWVYVIRIKCESNTVTQSRLMSIVSALFPKGSRSVVPRDTPLNIFVKIIQFIAQERLDFAMKEIIFDLLSVGKSAKTFTINPERMNIGLRVFLVIADSLQQKDGDPPMPTTGVILPSGNTLRVKKIFLNKTLTDEEAKVIGMSVYYPQVRRALDSILRHLDKEVGRPMCMTSVQMSNKEPEDMITGERKPKIDLFRTCIAAIPRLIPDGMSRTDLIELLARLTIHMDEELRALAFNTLQALMLDFPDWREDVLSGFVYFIVREVTDVHPTLLDNAVKMLVQLINQWKQAAQMYNRTQDSQSISNGGPHPPPLERSLYSTVFHVVEGFALVILCSSRPATRRLAVSVLREIRALFALLEVPKGDEELAIDVMDRLSPSILESFIHLTGADQTTLLYCPSSVDLQTLADWNSSPISHQFDVISPSHIWIFAHVTQGQDPWIISLSSFLKQENLPKHCSTAVSYAWMFAYTRLQLLSPQVDINSPINAKKVSTTTSSDSYVGLWRNYLILCCSAAASPSPSAPAGSVRCSPPETLASTPDSGYSIDSKIVGIPSPSSLFKHIVPMMRSESMEITESLVLGLGRTNPGAFRELIEELHPIIKEALERRPENMKRRRRRDILRVQLVRIFELLADAGVISHSASGGLDNETHFLNNTLLEYVDLTRQLLEAENEKDSDTLKDIRCHFSALVANIIQNVPVHQRRSIFPQQSLRHSLFMLFSHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNILDSLDKKVHQLGCEAVTLLLELNPDQSSLMYWAVDRCYTGSRRVAAGCFRAIANVFQNRDYQCDTVMLLNLILFKAADSSRSIYEVAMQLLQILEPKMFRYAHKLEVQRTDGVLSQLSPLPHLYSVSYYQLSEELARAYPELTLAIFSEISQRIQTAHPAGRQAMLHYLLPWMNNIELVDVRPLPSGRRQDEEDGSLKDRELMVTSRRWLRGEGWGSPQATAMVLNNLMYMTAKYGDELAWSEVENVWTTLADGWPKNLKIILHFLISICGVNSEPSLLPYVKKVIVYLGRDKTMQLLEELVSELQLTDPVSSGVTHMDNPPYYRITSGCKIPSVTSGTTSSSNTMVAPTDGNPDSKALKENFEESFVHLDIYGGLNSHLNRQHHRLESRYSSSSGGSYEEEKSDSMPLYSNWRLKVMEHNQGEPLPFPPAGGCWSPLVDYVPETASPGLPLHRCSIAVILLTDLIIDHSVKVEWGSYLHLLLHAVFIGFDHCHPEVYEHCKRLLLHLLIVMGPNSNIRTVASVLLRNKEFNEPRVLTVKPTAHSDYTFTAGINDFTPDYQPSPMTDSGLSSSSTSSSISLGNNSAAISHLQATLLGEVDLSVEQDGKVKTLMEFITSRKRGPLWNHEDVSSKNPSIKSADQLTTFLKHVVSVFKQSNAEGIHLERHLSEVALQTALSCSSRHYAGRSFQIFRALKQPLSANTLSDVLSRLVETVGDPGEDAQGFVIELLLTLESAIDTLAETMKHYDLLSALSQTSYHDPVMGNKYAANRKSTGQLNLSTSPINSSSHLGCNGDTRSNSLRLSLVGDRRGDRRRSNTLDITDGRTNHGGSLVRTRSLSSLREKGVYDTQPPTEPGNLMATIFWIATSLLESDYEYEYLLALRLLSKLLTHLPLDKSESREKIESVQSKLKWSNFPGLQQLFLKGFTSVSTQEMTVYLLSQLISVSKHTLVDPSQLSGFPLNILCLLPHLIQHFDNPTQFCKETASRIAKVCAEEKCPTLVNLAHMMSLYSTHTYSRDCANWINVVCRYLHDSFSEATFSLVTYLAELLEKGLASMQQSLLQIIYSLLSHVDLSAAPAKQFNLEITKTIGKYVQSPYWKEALNILKLVVSRSASLVVPNDIPKAYGVDVGSPEISFAKIFNNVSKELPGKTLDFHFDISETPIIGNKYGGQHSAAGRNGKAKVIAVTRSTSSTSSGSTSNALVPVSWKRPQLSQRRTREKLMSVLSLCGPESGLPKNPSVIFSSNEDLEVGDQQTSLISTTEDIIQEEEVAVEDSSSEQQFGVFKDFDFLDVELEDAEGESMDNFNWGVRRRSLDSIDKGDTPSLQECPCSSSTPSLTLTNQEDTDESSEEEAALTASQILSRTQMLNSDCVPDDLMPDHQDLLQSQDSASSNTTEDVLQIRDETPSLEACLDNASCQLPEDTSSVLKEEHVTAFEDEGPYLIQDQQDPLVCRGILDLEETDMPEPLAPESYPESVCEEDVTLALKELDERCEEEEADFSGLSSQEEDEQDGFPEVQTSPLPTPFLSAIIAAFQPMAYEDEEEAWRCHVNQTLSDTDGSCAVFTFHVFSRLFQTIQRKFGEITNEAVGFLGKSLQRIGTKFKSSLEVMMTCSECPTVFVDAETLMACGLLETLKFGVLELQEHLDTYTTKREAAEQWLDNCKRTFGANEDIDRINTNAHELELCRRLYRLHFQLLLLFQAYCKLINQVNAIKNEAEVINMSEELTQLEGILKEAEAASENEETDISKAAQTTIETAIHSLIETLKNKEFVSAVAQVKAFRTLWPSDIFGSCDDDPVQTLLHIYFHHQTLGQTGSFAVIGSNLDMSEANCKLMELNLEIRESLRMVQSHPLLAQAKPVGKTASAGF", "length": 3118 }, "evidence": [ { "id": "FB:FBgn0016081", "url": "https://alliancegenome.org/gene/FB:FBgn0016081#orthology", "database": "AGR" }, { "id": "SGD:S000001391", "url": "https://alliancegenome.org/gene/SGD:S000001391#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q8I9-1", "protein_name": "Protein furry homolog", "gene_name": "Fry", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQDSGFFEISIKYLLKSWSNASPVGNGYIKPPVPPASGTHREKGPPAMLPINVDPDSKPGEYVLKSLFVNFTTQAERKIRIIMAEPLEKPLTKSLQRGEDPQFDQVISSMSSLSEYCLPSILRTLFDWYKRQNGIEDESHEYRPRTSNKSKSDEQQRDYLMERRDLAIDFIFSLVLIEVLKQIPLHPVIDSLIHDIINLAFKHFKYKEGYLGPNTGNMHIVADLYAEVIGVLAQAKFPAVKKKFMAELKELRHKEQSPYVVQSIISLIMGMKFFRIKMYPVEDFEASLQFMQECAHYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLELSSRKKHSLALYPLVTCLLCVSQKQLFLNRWHVFLNNCLSNLKNKDPKMARVALESLYRLLWVYMIRIKCESNTATQSRLITITTTLFPKGSRGVVPRDMPLNIFVKIIQFIAQERLDFAMKEIIFDFLCVGKPAKAFSLNPERMNIGLRAFLVIADSLQQKDGEPPMPVTGAVLPSGNTLRVKKTYLSKTLTEEEAKMIGMSLYYSQVRKAVGNILRHLDKEVGRCMMLTNVQMLNKEPEDMITGERKPKIDLFRTCVAAIPRLLPDGMSKLELIDLLARLSIHMDDELRHIAQNSLQGLLVDFSDWREDVLFGFTNFLLREVNDMHHTLLDSSLKLLLQLLTQWKLVIQTQGRAYEQANKIRNSELIPNGSSHRMQSERGPHCSVLHAVEGFALVLLCSFQVATRKLSVLILKEIRALFLALGQPEDDDRPMIDVMDQLSSSILESFIHVAVSDSATLPPTHNVDLQWLVEWNAVLVNSHYDVKSPSHVWIFAQSVKDPWVLCLFSFLRQENLPKHCPTALSYAWPYAFTRLQSVMPLVDPNSPVNAKKTSTASSGDNYVTLWRNYLILCFGVAKPSIMSPGHLRASTPEIMATTPDGTVSYDNKAIGTPSVGVLLKQLVPLMRLESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAENDKEVEILKDIRAHFSAMVANLIQCVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVMLLLELNPDQINLFNWAIDRCYTGSYQLASGCFKAIATVCGNRNYPFDIVTLLNLVLFKASDTNREIYEVSMQLMQILEAKLFVHSKKVAEQRPGSILYGTHGPLPPLYSVSLALLSCELARMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLHNIELVDSRLLLPGSSPSSPEDEVKDREGEVTASHGLKGNGWGSPEATSLVLNNLMYMTAKYGDEVPGAEMENAWNALANNEKWSNNLRVTLQFLISLCGVSSDTILLPYIKKVATYLCRNNTIQTMEELLFELQQTEPVNPIVQHCDNPPFYRFTASSKASAAASGTTSSSNTVVAGQDSFPDPEESKILKESDDRFSNVIRAHTRLESRYSNSSGGSYDEDKNDPISPYTGWLLSITEAKQPQPLPMPCSGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLHAVFLGLDHYRPEVFEHSKKLLLHLLIALSCNSNFHAIASVLLQTREMGEAKTLTMQPAYQPEYLYTGGFDFLREDQSSPVPDSGLNSSSTSSSISLGGSSGNLPQMTQEVEDVEAATETDEKASKLIEFLTTRAFGPLWCHEDITPKNQNSKSAEQLSNFLRHVVSVFKDSRSGFHLEQHLSEVALQTALASSSRHYAGRSFQIFRALKQPLSAHALSDLLSRLVEVIGEHGDEIQGYVMEALLTLEAAVDNLSDCLKNSDLFTVLSRSSSPDLSSSSKLTASRKSTGQLNVNPGTPGSGGGGGGSGNTTTAERSRHQRSFSVPKKFGVVDRSSDPPRSATLDRIQACTQQGLSSKTRSNSSLKESLTDPSHVSHPTNLLATIFWVTVALMESDFEFEYLMALRLLNRLLAHMPLEKAENREKLEKLQAQLKWADFPGLQQLLLKGFTSLTTTDLTLQLFSLLTSVSKVPMVDSSQAIGFPLNVLCLLPQLIQHFENPNQFCKDIAERIAQVCLEEKNPKLSNLAHVMTLYKTHSYTRDCATWVNVVCRYLHEAYADITLNMVTYLAELLEKGLPSMQQPLLQVIYSLLSYMDLSVVPVKQFNMEVLKTIEKYVQSIHWREALNILKLVVSRSASLVLPSYQHSDLSKIELHRVWTSASKELPGKTLDFHFDISETPIIGRRYDELQNSSGRDGKPRAMAVTRSASSTSSGSNSNVLVPVSWKRPQYSQKRTKEKLVHVLSLCGQEVGLSKNPSVIFSSCGDLDLPEHQTSLVSSEDGPREQENMDDTNSEQQFRVFRDFDFLDVELEDGEGESMDNFNWGVRRRSLDSLDKCDMQILEERQLSRSTPSLNKMSHEDSDESSEEDLTASQILEHSDLIMNLSPSEEANPMELLTSACDSAPADPHSFNTRMANFEASLPDINNLQISEGSKAEAVPEEEDTTVHEDDLSSSINELPAAFECSDSFSLDMTEAEEKGNRGLDQYTLASFGEGDRGVSPPPSPFFSAILAAFQPAACDDAEEAWRSHINQLMCDSDGSCAVYTFHVFSSLFKNIQKRFCFLTCDAASYLGDNLRGIGSKFVSSSQMLTSCSECPTLFVDAETLLSCGLLDKLKFSVLELQEYLDTYNNRKEATLSWLANCKATFAGGSRDGVITCQPGDSEEKQLELCQRLYKLHFQLLLLYQSYCKLIGQVHEVSSVPELLNMSRELSDLKRNLKEATAAIATDPLYIEGAWSEPTFTSTEAAIQSMLECLKNNELGKALRQIKECRSLWPNDIFGSSSDDEVQTLLNIYFRHQTLGQTGTYALVGSNHSLTEICTKLMELNMEIRDMIRRAQNYRVLTAFLPDSSVSGTSL", "length": 3020 }, "evidence": [ { "id": "RGD:1307034", "url": "https://alliancegenome.org/gene/RGD:1307034#orthology", "database": "AGR" }, { "id": "MGI:2443895", "url": "https://alliancegenome.org/gene/MGI:2443895#orthology", "database": "AGR" }, { "id": "HGNC:20367", "url": "https://alliancegenome.org/gene/HGNC:20367#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060510-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060510-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0016081", "url": "https://alliancegenome.org/gene/FB:FBgn0016081#orthology", "database": "AGR" }, { "id": "SGD:S000001391", "url": "https://alliancegenome.org/gene/SGD:S000001391#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQ05-1", "protein_name": "FRY like transcription coactivator", "gene_name": "Fryl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSITIDPDVKPGEYVIKSLFAEFAVQAEKKIEVVMAEPLEKLLSRSLQRGEDLQFDQLVSSMSSVAEHCLPSLLRTLFDWYRRQNGTDDESYGYRPRSSTKSKGDEQHRERDYLLERRDLAVDFIFCLVLVEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSGTNTGNVHIIADLYAEVIGVLAQSKFQAVRKKFVTELKELRQKEQSPHVVQSVISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTTFELSSRKKHSLALYPLITCLLCVSQKQFFLNNWHIFLQNCLSHLKNKDPKMSRVALESLYRLLWVYVIRIKCESNTVTQSRLMSIVSALFPKGSRSVVPRDTPLNIFVKIIQFIAQERLDFAMKEIIFDLLSVGKSTKTFTINPERMNIGLRVFLVIADSLQQKDGDPPMPTTGVILPSGNTLRVKKIFLNKTLTDEEAKVIGMSVYYPQVRKALDSILRHLDKEVGRPMCMTSVQMSNKEPEDMITGERKPKIDLFRTCIAAIPRLIPDGMSRTDLIELLARLTIHMDEELRALAFNTLQALMLDFPDWREDVLSGFVYFIVREVTDVHPTLLDNAVKMLVQLINQWKQAAQMYNRTQDSQHGIANGGPHPPPLERNPYSTVFHVVEGFALVILCSSRPATRRLAVSVLREIRALFALLEVPKGDDELAIDVMDRLSPSILESFIHLTGADQTTLLYCPSSVDLQTLADWNSSPISHQFDVISPSHIWIFAHVTQGQDPWIISLSSFLKQENLPKHCSTAVSYAWMFAYTRLQLLSPQVDINSPINAKKVNATTSSDSYIGLWRNYLVLCCSAATSPSPSAPAGSVRCSPPETLASTPDSGYSIDSKIVGIPSPSSLFKHIVPMMRSESMEITESLVLGLGRTNPGVFRELIEELHPIIKEALERRPENMKRRRRRDILRVQLVRIFELLADAGVISHSASGGLDSETHFLNNTLLEYVDLTRQLLEAENEKDSDTLKDIRCHFSALVANIIQNVPVHQRRSIFPQQSLRHSLFMLFSHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNILDSLDKKVHQLGCEAVTLLLELNPDQSSLMYWAVDRCYTGSRRVAAGCFKAIANVFQNRDYQCDTVMLLNLILFKAADSSRSIYEVAMQLLQILEPKMFRYAHKLEVQRTDGVLSQLSPLPHLYSVSYYQLSEELARAYPELTLAIFSEISQRIQTAHPAGRQAMLHYLLPWMNNIELVDLKPLPSGRRQDEDEDDSLKDRELMVTSRRWLRGEGWGSPQATAMVLNNLMYMTAKYGDELAWSEVENVWTTLADGWPKNLKIILHFLISICGVNSEPSLLPYVKKVIVYLGRDKTMQLLEELVSELQLTDPVSSGVTHMDNPPYYRITSSCKIPSVTSGTTSSSNTMVAPTDGNPDSKALKENFEESYVHLDIYGGLNSHLNRQHHRLESRYSSSSGGSYEEEKSDSMPLYSNWRLKVMEHNQGEPLPFPPAGGCWSPLVDYVPETASPGLPLHRCNIAVILLTDLIIDHSVKVEWGSYLHLLLHAIFIGFDHCHPEVYEHCKRLLLHLLIVMGPNSDIRTVASVLLRDKEFNEPRVLTVKQTAHSDYTFTAGINDFTPDYQPSPMTDSGLSSSSTSSSISLGNNSAAISHLHTTLLGEVDLSVEQDGKVKTLMEFITSRKRGPLWNHEDVSSKNPSIKSADQLATFLKHVVSVFKQSNAEGIHLERHLSEVALQTALSCSSRHYAGRSFQIFRALKQPLSADTLSDVLSRLVETVGDPGEDAQGFVIELLLTLESAIDTLAETMKHYDLLSALSQSSYHDPVMGNKYAANRKSTGQLNLSTSPINSSGHLGCNGDTRSNSLRLSLVGDRRGDRRRSNTLDITDGRINHGGSLARTRSLSSLREKGVYDTQPPTEPSNLMATIFWIATSLLESDYEYEYLLALRLLSKLLTHLPLDKSESREKIENVQSKLKWSNFPGLQQLFLKGFTSVSTQEMTVHLLSQLISVSKHTLVDPSQVSGFPLNILCLLPHLIQHFDSPTQFCKETASRIAKVCAEEKCPTLVNLAHMMSLYSTHTYSRDCSNWINVVCRYLHDSFSEATFSLVTYLAELLEKGLSSMQQSLLQIIYSLLSHIDLSAAPVKQFNLEIIKIIGKYVQSPYWKEALNILKLVVSRSASLVVPNDIPKAYGVDVGSPEISFAKIFNNVSKELPGKTLDFHFDISETPIIGNKYGGQHSAAGRNGKAKVIAVTRSTSSTSSGSTSNALVPVSWKRPQLSQRRTREKLMSVLSLCGPESGLPKNPSVVFSSNEDLEVGDQQTSLISTTEDIIQEEEVAVEDNSSEQQFGVFKDFDFLDVELEDAEGESMDNFNWGVRRRSLDSIDKGDTPSLQEYPCSSSTPSLTLTNQEDTDESSEEEAALTASQILSRTQMLNSDCVTEDMMPEHQDLLQSQDSASSNTTEDVLQIRDETPSLEACLDNASSQLPEGTSSVLKEEHVTAFEDEGSYVIPDQQDPLVCRGILDLEETDMPEPLAPESYPESICEEDVTLALKELDERCEEEEADFSGLSSQEEDEQDGFPEVQTSPLPTPFLSAIIAAFQPMAYEDEEEAWRCHVNQTLSDTDGSCAVFTFHVFSRLFQTIQRKFGEITKEAVGFLGESLQRIGTKFKSSLEVMMACSECPTVFVDAETLMACGLLETLKFGVLELQEHLDTYTTKREAAEQWLDNCKRTFGANEDIYRMNTNAHELELCRRLYRLHFQLLLLFQAYCKLINQVNTIKNEAEVINMSEELAQLEGILKEAEAASENEEIDISKAAQTTIETAIHSLIETLKNKEFVSAVAQVKAFRTLWPNDIFGSCDDDPVQTLLHIYFHHQTLGQTGSFAVISSNLDMSEANCKLMELNLEIRESLRTVQSYPLLAQTKPVGNMTSTGF", "length": 3007 }, "evidence": [ { "id": "FB:FBgn0016081", "url": "https://alliancegenome.org/gene/FB:FBgn0016081#orthology", "database": "AGR" }, { "id": "SGD:S000001391", "url": "https://alliancegenome.org/gene/SGD:S000001391#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O94915-1", "protein_name": "Protein furry homolog-like", "gene_name": "FRYL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNITIDPDVKPGEYVIKSLFAEFAVQAEKKIEVVMAEPLEKLLSRSLQRGEDLQFDQLISSMSSVAEHCLPSLLRTLFDWYRRQNGTEDESYEYRPRSSTKSKGDEQQRERDYLLERRDLAVDFIFCLVLVEVLKQIPVHPVPDPLVHEVLNLAFKHFKHKEGYSGTNTGNVHIIADLYAEVIGVLAQSKFQAVRKKFVTELKELRQKEQSPHVVQSVISLIMGMKFFRVKMYPVEDFEASFQFMQECAQYFLEVKDKDIKHALAGLFVEILIPVAAAVKNEVNVPCLKNFVEMLYQTTFELSSRKKHSLALYPLITCLLCVSQKQFFLNNWHIFLQNCLSHLKNKDPKMSRVALESLYRLLWVYVIRIKCESNTVTQSRLMSIVSALFPKGSRSVVPRDTPLNIFVKIIQFIAQERLDFAMKEIIFDLLSVGKSTKTFTINPERMNIGLRVFLVIADSLQQKDGEPPMPTTGVILPSGNTLRVKKIFLNKTLTDEEAKVIGMSVYYPQVRKALDSILRHLDKEVGRPMCMTSVQMSNKEPEDMITGERKPKIDLFRTCIAAIPRLIPDGMSRTDLIELLARLTIHMDEELRALAFNTLQALMLDFPDWREDVLSGFVYFIVREVTDVHPTLLDNAVKMLVQLINQWKQAAQMHNKNQDTQHGVANGASHPPPLERSPYSNVFHVVEGFALVILCSSRPATRRLAVSVLREIRALFALLEIPKGDDELAIDVMDRLSPSILESFIHLTGADQTTLLYCPSSIDLQTLAEWNSSPISHQFDVISPSHIWIFAHVTQGQDPWIISLSSFLKQENLPKHCSTAVSYAWMFAYTRLQLLSPQVDINSPINAKKVNTTTSSDSYIGLWRNYLILCCSAATSSSSTSAGSVRCSPPETLASTPDSGYSIDSKIIGIPSPSSLFKHIVPMMRSESMEITESLVLGLGRTNPGAFRELIEELHPIIKEALERRPENMKRRRRRDILRVQLVRIFELLADAGVISHSASGGLDNETHFLNNTLLEYVDLTRQLLEAENEKDSDTLKDIRCHFSALVANIIQNVPVHQRRSIFPQQSLRHSLFMLFSHWAGPFSIMFTPLDRYSDRNMQINRHQYCALKAMSAVLCCGPVADNVGLSSDGYLYKWLDNILDSLDKKVHQLGCEAVTLLLELNPDQSNLMYWAVDRCYTGSGRVAAGCFKAIANVFQNRDYQCDTVMLLNLILFKAADSSRSIYEVAMQLLQILEPKMFRYAHKLEVQRTDGVLSQLSPLPHLYSVSYYQLSEELARAYPELTLAIFSEISQRIQTAHPAGRQVMLHYLLPWMNNIELVDLKPLPTARRHDEDEDDSLKDRELMVTSRRWLRGEGWGSPQATAMVLNNLMYMTAKYGDELAWSEVENVWTTLADGWPKNLKIILHFLISICGVNSEPSLLPYVKKVIVYLGRDKTMQLLEELVSELQLTDPVSSGVTHMDNPPYYRITSSYKIPSVTSGTTSSSNTMVAPTDGNPDNKPIKENIEESYVHLDIYSGLNSHLNRQHHRLESRYSSSSGGSYEEEKSDSMPLYSNWRLKVMEHNQGEPLPFPPAGGCWSPLVDYVPETSSPGLPLHRCNIAVILLTDLIIDHSVKVEWGSYLHLLLHAIFIGFDHCHPEVYEHCKRLLLHLLIVMGPNSNIRTVASVLLRNKEFNEPRVLTVKQVAHLDYNFTAGINDFIPDYQPSPMTDSGLSSSSTSSSISLGNNSAAISHLHTTILNEVDISVEQDGKVKTLMEFITSRKRGPLWNHEDVSAKNPSIKSAEQLTTFLKHVVSVFKQSSSEGIHLEHHLSEVALQTALSCSSRHYAGRSFQIFRALKQPLTATTLSDVLSRLVETVGDPGEDAQGFVIELLLTLESAIDTLAETMKHYDLLSALSQTSYHDPIMGNKYAANRKSTGQLNLSTSPINSSSYLGYNSNARSNSLRLSLIGDRRGDRRRSNTLDIMDGRINHSSSLARTRSLSSLREKGMYDVQSTTEPTNLMATIFWIAASLLESDYEYEYLLALRLLNKLLIHLPLDKSESREKIENVQSKLKWTNFPGLQQLFLKGFTSASTQEMTVHLLSKLISVSKHTLVDPSQLSGFPLNILCLLPHLIQHFDSPTQFCKETASRIAKVCAEEKCPTLVNLAHMMSLYSTHTYSRDCSNWINVVCRYLHDSFSDTTFNLVTYLAELLEKGLSSMQQSLLQIIYSLLSHIDLSAAPAKQFNLEIIKIIGKYVQSPYWKEALNILKLVVSRSASLVVPSDIPKTYGGDTGSPEISFTKIFNNVSKELPGKTLDFHFDISETPIIGNKYGDQHSAAGRNGKPKVIAVTRSTSSTSSGSNSNALVPVSWKRPQLSQRRTREKLMNVLSLCGPESGLPKNPSVVFSSNEDLEVGDQQTSLISTTEDINQEEEVAVEDNSSEQQFGVFKDFDFLDVELEDAEGESMDNFNWGVRRRSLDSIDKGDTPSLQEYQCSSSTPSLNLTNQEDTDESSEEEAALTASQILSRTQMLNSDSATDETIPDHPDLLLQSEDSTGSITTEEVLQIRDETPTLEASLDNANSRLPEDTTSVLKEEHVTTFEDEGSYIIQEQQESLVCQGILDLEETEMPEPLAPESYPESVCEEDVTLALKELDERCEEEEADFSGLSSQDEEEQDGFPEVQTSPLPSPFLSAIIAAFQPVAYDDEEEAWRCHVNQMLSDTDGSSAVFTFHVFSRLFQTIQRKFGEITNEAVSFLGDSLQRIGTKFKSSLEVMMLCSECPTVFVDAETLMSCGLLETLKFGVLELQEHLDTYNVKREAAEQWLDDCKRTFGAKEDMYRINTDAQQMEILAELELCRRLYKLHFQLLLLFQAYCKLINQVNTIKNEAEVINMSEELAQLESILKEAESASENEEIDISKAAQTTIETAIHSLIETLKNKEFISAVAQVKAFRSLWPSDIFGSCEDDPVQTLLHIYFHHQTLGQTGSFAVIGSNLDMSEANYKLMELNLEIRESLRMVQSYQLLAQAKPMGNMVSTGF", "length": 3013 }, "evidence": [ { "id": "FB:FBgn0016081", "url": "https://alliancegenome.org/gene/FB:FBgn0016081#orthology", "database": "AGR" }, { "id": "SGD:S000001391", "url": "https://alliancegenome.org/gene/SGD:S000001391#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P40468-1", "protein_name": "Cell morphogenesis protein PAG1", "gene_name": "TAO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MASRFTFPPQRDQGIGFTFPPTNKAEGSSNNNQISIDIDPSGQDVLEEINEAPLNTFPLHQSVTDAPIIDIPSPTDMSEGTSLNNQLLLRQQQQQGTGEGQALPPTFVEEQSDQNKISMLLPEQKQQRMQESAPPDITAKSVAEDYVTTLRQQMATDWKSPSEYALHILFTKFIRYAENKLNMCLQQLDMAEPPIVEILGEGVDPSFDEIIKSLGHIAKKKPKPVIDAMMFWRKTKSEAANSASEEMEKLLKEYEFEKAHPSQAHFLMNRRLSRSSSNTTSKYKHNNNTNNLPGMKRHVSSSFNNKVPLIKASSSNNSATSSPSIANSQLKSLENTIEVAKEEAFLADRKSLISIYILCRVLNEIVKQASSNEEEDLSDKLEEIVFTQLKTTDPLSISTSLIKSSNWNSFAELLGSMSEKKFLSVSDRFIADLEKIPAYIPPELEPSTHLLILGMRYLKLRNYPLEKFEESADFMKSLSKFFAKTENFPVCLAYAEVTNQLLLPLAGSLTAEVNHPTWVEAMSTLLNTAKRLQADSKYWVSGFKLTVSILCASPPDLFSKQWLSLLEANASKVKSKSLNERIIFAVGLSRLVWVYLYRCPETLNNTTRTLTKLLQLYLNTRKKENWITGDFGLLNPLTDALISIGFLHPNFLMEQALIPLIRQSFNGSNLENINYEKLILTINTYKGLLVTKERPRFPEDDNRLYELNLNNITVNQVQEASSINHTEISDYFYKLFLLLDSSIGSEVWSPENQHQKQSSNAFSPFGFSFSNDNDSSKNKSLYVILFGTIIEAIPCCLSISRTIPYKSTIEILSRNAVHSEVIISSSSQNALRALASKKNPYTLITWFAKYSFDFDEKTQSSYNMSYLSSKEYNRLLILYVELLECWLEEFQSSNKEENKKETGLDGIRLLPIDAEQEESNETEKLEWKNTVTVIEEVEGNGLFFLCSHDAKIRRLGIQILRIIFKFDEAMMEKTEKLSNGHSRSSSHFAADRGTRLIDLLNECNTTTLINPHKATLSAVEKTRFSRLNSKYKRGLLIKLAESEYGVDAALWQRAFPKLLALVFKTCPMAMALCRSIVCIRLVQVHEIILRVANDVDFKLKNVLPETIVNQWKLYLIAACTSLTSTFDQKLHIPSNIPQHGRKKSQQIFTVQHQKIKSAKSIFKMVLPLLNAKYIMIRDAIITGLSSMNINIFKAYVEAIDVFLVAWKEGSSNNQIRVEMFHILTILSPYLKSDMIFNDEWILRKLSEFLQKTKQFLEKDSVQISYEYQSLRSYFAGLILSYYMAVREHPLIDELFPFQARASCFNFLKEWCGYGEYEPISEERYAIMIKNTESGRDRTAITTGIEFQKNRLQMIVLETMVVLCSDPITQTLDDDLELPIVISFDTEDLLAWIEALFDSDNTTVKNLGVRALENLLDKNRENFKLFRDVAFQCVSHHSHPSVAVLYYTTLCKSVLKLDNLVLDEDELVSLGLYGLVADKEDTRTFAVDLLSAVETKLHNSSYTKVFKERLANSSKTVYKSTAKEISSIFAELLSQDLCLRIFSSLVRILDLFPFEIKRDLLVLMVPWVNKFTLKSLEELDTFMVLNNLFYITIDLNDSLPNEVEQLWISLGKGNSFQNIHVSLEYIINSSMNHCNPLFVQYARDIVLYLANIPGGIGLLDTLLNNLEPKYMVPLAKHTFNEPMNNNKYSFLGNIWERLNYNGKRIIFSKAQLSIIFLVNLLTNLSESVKAKIPLLLHMSICLLDHYVPLIHESACKIASTLIFGLAPSHEKSEETVKLLRNKHALWSYDNLMKKGARSPKTMDLLIRNIISIFSDLDEFQVTWQRIALKWATTCSVRHIACRSFQIFRSLLTFLDQEMLRDMLHRLSNTISDGNVDIQGFAMQILMTLNAIMAELDPTNLISFPQLFWSITACLSSIHEQEFIEVLSCLSKFISKIDLDSPDTVQCLVAIFPSNWEGRFDGLQQIVMTGLRSANSLEITWKFLDKLNLLKDSRIIANTESRLLFALIANLPRFLNAMDRKDFTGIQVAADSLIELANAYKQPSLSRLIDSLAKNKFRSKKDFMSQVVSFISRNYFPSYSAQTLVFLLGLLFNKIGWIRVQTLEILKYVFPLIDLRRPEFIGVGADLISPLLRLLFTEYEAKALEVLDCVPNVSGSKMDKDVLRITMGNKDVKDGDNATTTLFGLPEDSGWSVPMPTMTAATTRHNVHAVFMTCGTGKSDEVSAHGSDDMDAVIEFHADGDYELGRMDTIVEFHADGDYDLGRMDTNDSISVAEEKDASLSHMWAELDNLDSFFTKDTNVPNISSKMGMGIPHGRSDSIETTRTDQTFSFESAPQLYDKKVSVILNRSLSRTPSNVSFKTHLADSFAVKINRNGKPRI", "length": 2376 }, "evidence": [ { "id": "RGD:1307034", "url": "https://alliancegenome.org/gene/RGD:1307034#orthology", "database": "AGR" }, { "id": "MGI:2443895", "url": "https://alliancegenome.org/gene/MGI:2443895#orthology", "database": "AGR" }, { "id": "HGNC:20367", "url": "https://alliancegenome.org/gene/HGNC:20367#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060510-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060510-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0016081", "url": "https://alliancegenome.org/gene/FB:FBgn0016081#orthology", "database": "AGR" }, { "id": "SGD:S000001391", "url": "https://alliancegenome.org/gene/SGD:S000001391#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5TBA9-1", "protein_name": "Protein furry homolog", "gene_name": "FRY", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASQQDSGFFEISIKYLLKSWSNTSPVGNGYIKPPVPPASGTHREKGPPTMLPINVDPDSKPGEYVLKSLFVNFTTQAERKIRIIMAEPLEKPLTKSLQRGEDPQFDQVISSMSSLSEYCLPSILRTLFDWYKRQNGIEDESHEYRPRTSNKSKSDEQQRDYLMERRDLAIDFIFSLVLIEVLKQIPLHPVIDSLIHDVINLAFKHFKYKEGYLGPNTGNMHIVADLYAEVIGVLAQAKFPAVKKKFMAELKELRHKEQNPYVVQSIISLIMGMKFFRIKMYPVEDFEASLQFMQECAHYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCLRNFVESLYDTTLELSSRKKHSLALYPLVTCLLCVSQKQLFLNRWHIFLNNCLSNLKNKDPKMARVALESLYRLLWVYMIRIKCESNTATQSRLITIITTLFPKGSRGVVPRDMPLNIFVKIIQFIAQERLDFAMKEIIFDFLCVGKPAKAFSLNPERMNIGLRAFLVIADSLQQKDGEPPMPVTGAVLPSGNTLRVKKTYLSKTLTEEEAKMIGMSLYYSQVRKAVDNILRHLDKEVGRCMMLTNVQMLNKEPEDMITGERKPKIDLFRTCVAAIPRLLPDGMSKLELIDLLARLSIHMDDELRHIAQNSLQGLLVDFSDWREDVLFGFTNFLLREVNDMHHTLLDSSLKLLLQLLTQWKLVIQTQGKVYEQANKIRNSELIANGSSHRIQSERGPHCSVLHAVEGFALVLLCSFQVATRKLSVLILKEIRALFIALGQPEDDDRPMIDVMDQLSSSILESFIHVAVSDSATLPLTHNVDLQWLVEWNAVLVNSHYDVKSPSHVWIFAQSVKDPWVLCLFSFLRQENLPKHCPTALSYAWPYAFTRLQSVMPLVDPNSPINAKKTSTAGSGDNYVTLWRNYLILCFGVAKPSIMSPGHLRASTPEIMATTPDGTVSYDNKAIGTPSVGVLLKQLVPLMRLESIEITESLVLGFGRTNSLVFRELVEELHPLMKEALERRPENKKRRERRDLLRLQLLRIFELLADAGVISDSTNGALERDTLALGALFLEYVDLTRMLLEAENDKEVEILKDIRAHFSAMVANLIQCVPVHHRRFLFPQQSLRHHLFILFSQWAGPFSIMFTPLDRYSDRNHQITRYQYCALKAMSAVLCCGPVFDNVGLSPDGYLYKWLDNILACQDLRVHQLGCEVVVLLLELNPDQINLFNWAIDRCYTGSYQLASGCFKAIATVCGSRNYPFDIVTLLNLVLFKASDTNREIYEISMQLMQILEAKLFVYSKKVAEQRPGSILYGTHGPLPPLYSVSLALLSCELARMYPELTLPLFSEVSQRFPTTHPNGRQIMLTYLLPWLHNIELVDSRLLLPGSSPSSPEDEVKDREGDVTASHGLRGNGWGSPEATSLVLNNLMYMTAKYGDEVPGPEMENAWNALANNEKWSNNLRITLQFLISLCGVSSDTVLLPYIKKVAIYLCRNNTIQTMEELLFELQQTEPVNPIVQHCDNPPFYRFTASSKASAAASGTTSSSNTVVAGQENFPDAEENKILKESDERFSNVIRAHTRLESRYSNSSGGSYDEDKNDPISPYTGWLLTITETKQPQPLPMPCTGGCWAPLVDYLPETITPRGPLHRCNIAVIFMTEMVVDHSVREDWALHLPLLLHAVFLGLDHYRPEVFEHSKKLLLHLLIALSCNSNFHSIASVLLQTREMGEAKTLTVQPAYQPEYLYTGGFDFLREDQSSPVPDSGLSSSSTSSSISLGGSSGNLPQMTQEVEDVDTAAETDEKANKLIEFLTTRAFGPLWCHEDITPKNQNSKSAEQLTNFLRHVVSVFKDSKSGFHLEHQLSEVALQTALASSSRHYAGRSFQIFRALKQPLSAHALSDLLSRLVEVIGEHGDEIQGYVMEALLTLEAAVDNLSDCLKNSDLLTVLSRSSSPDLSSSSKLTASRKSTGQLNMNPGTTSGNTATAERSRHQRSFSVPKKFGVIDRSSDPPRSATLDRIQACTQQGLSSKTRSSSSLKDSLTDPSHINHPTNLLATIFWVTVALMESDFEFEYLMALRLLSRLLAHMPLDKAENREKLEKLQAQLKWADFSGLQQLLLKGFTSLTTTDLTLQLFSLLTPVSKISMVDASHAIGFPLNVLCLLPQLIQHFENPNQFCKDIAERIAQVCLEEKNPKLSNLAHVMTLYKTHSYTRDCATWVNVVCRYLHEAYADITLNMVTYLAELLEKGLPSVQQPLLQVIYSLLSYMDLSVVPVKQFNVEVLKTIEKYVQSVHWREALNILKLVVSRSASLVLPSYQHSDLSKIEIHRVWTSASKELPGKTLDFHFDISETPIIGRRYDELQNSSGRDGKPRAMAVTRSTSSTSSGSNSNVLVPVSWKRPQYSQKRTKEKLVHVLSLCGQEVGLSKNPSVIFSSCGDLDLLEHQTSLVSSEDGAREQENMDDTNSEQQFRVFRDFDFLDVELEDGEGESMDNFNWGVRRRSLDSLDKCDMQILEERQLSGSTPSLNKMHHEDSDESSEEEDLTASQILEHSDLIMTLSPSEETNPMELLTTACDSTPAEPHSFNTRMSSFDASLPDMNNLQISEGSKAEAVREEEDTTVHEDDLSSSINELPAAFECSDSFSLDMTEGEEKGNRALDQFTLASFGEGDRGVSPPPSPFFSAILAAFQPAACDDAEEAWRSHINQLMCDSDGSCAVYTFHVFSSLFKNIQKRFCFLTCDAASYLGDNLRGIGSKFVSSSQMLTSCSECPTLFVDAETLLSCGLLDKLKFSVLELQEYLDTYNNRKEATLSWLANCKATFAGGSRDGVITCQPGDSEEKQLELCQRLYKLHFQLLLLFQSYCKLIGQVHEVSSMPELLNMSRELSDLKKHLKEASAVIAADPLYSDGAWSEPTFTSTEAAIQSMLECLKNNELGKALRQIRECRSLWPNDIFGSSSDDEVQTLLNIYFRHQTLGQTGTYALVGSNQSLTEICTKLMELNMEIRDMIRRAQSYRVLTTFLPDSSVSGTSL", "length": 3013 }, "evidence": [ { "id": "RGD:1307034", "url": "https://alliancegenome.org/gene/RGD:1307034#orthology", "database": "AGR" }, { "id": "MGI:2443895", "url": "https://alliancegenome.org/gene/MGI:2443895#orthology", "database": "AGR" }, { "id": "HGNC:20367", "url": "https://alliancegenome.org/gene/HGNC:20367#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060510-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060510-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0016081", "url": "https://alliancegenome.org/gene/FB:FBgn0016081#orthology", "database": "AGR" }, { "id": "SGD:S000001391", "url": "https://alliancegenome.org/gene/SGD:S000001391#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VT28-1", "protein_name": "Protein furry", "gene_name": "fry", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDQLELQDDLFGLEAGVAGTNQNPNEQHLSDPAASPSTSSPANNNATAGAATTSTATVITAVGGAGGGVAAAGVGVVTPTKSPQRNAFQEDAYQANLAGGDSVDNIESAQLDGGNPSGGSPGQRHSINSAEYTSTPKTTRSGPNGSTTASGTTSPINYQLPGDDYPYGIEYESQQLLYQQQQQQQQQQSQQQQQQQQQQQQQLPVGDVEQSSAVTYQSLPVSRQSYASPPALIIPQRQSLLPWGAHSRSSIINVLPSYTQAEMHALAARVASVETSAPRPGEIVMRNLFSDFTAQAEKKIELVMLESADKNLSKLLQRGEDQQFDQLLSALGSVAEHCLPSLLHTLLAWHRRQLSDMEIKNDLKKPAPSGSSSQAATNKPTVDLDFQLQRREAAVEFIFCLALIEILKQLPYHPGHEDLVRSIENLAFKHFKYKDGLQNNPNALNIHMIADLYAEVIGVLAQSRFASVRKRFMSELKELRGKEVSPTTTQSIISLLMGMKFFRVKMVPIEEFEASFQFMHECGQYFLEVKDKDIKHALAGLFVEILVPVAAAVKNEVNVPCVKNFVELLYVQTLDASTKSKHRLALFPLVTCLLCVSQKTFFLTNWHYFLAMCLSNLKNRDAKMSRVALESLFRLLWVYMIRIKCESNSATHSRLQSIVNSLFPKGSKGVVPRDTPLNIFVKIIQFIAQERLDFAMREIVYDLLCVGRSIKLILNPERMSIGLRAFLVVADSLQQKAGEPPMPRTVPVLPSGNTLRVKKTFNKMYVLLTDDTARSIGMSTYFPHVRRVFVDILRALDVHYGRPLMMTNTQNQNKEPDEMLSGERKPRIDLFRTCVAAVPRLIPDTMTPHELVDMLSRLSVHMDEELRILTHQSLTTLVIDFPDWRQDVVHGYTQFLVRDVTDTYPQLLENCTRILFTFLNIWRCATNVNGNNTTSAPSGATNVVNTSQAKMTTATTTTTVVQATVVQVTSAPAKDTASSQLSKQQHLNTASSAASSITTSSGMSSITQHTVLNMASDVGKKNEIPLATTLHFVEGFALVLLCNYRTYLRKLAALILKEVKNLMRALGIPETEPPLIDVMDRCVPGIIEKCLPQLPQTEKTAILNANCIDLQWIAERSSGVWLAGLTDDNSKSSTSTLNLSQSSSTPNASATAASSPQLPFDPWATCLFGLLERQNVLQQCPSAVAQAWPICFTRLNALYSVIDPTPVSDNRASLLRSSAPTKKVPTESQKDSYLRLWRNQVACAMRLVPQIPSVAVRCASPDLSLSSSPDSLNADRSDKSAMGSASPQALYKLVVPLLRCEVVDVRDAAVNALGLINHDALKDLMEELVVYIREAVDCKQENMRRRRRRDALRLQVVRVLEKIAENGTFGVSTCVLERDTMSLHPTFVLYISGAMGYLTSETDKDNLSIREVKAHFCNFIRKMIKNFPLEACATLLSRVLKRNLFNLFAAWCGSFSKPLGYTMQSDHTLEEEKLQFSALQAMSALLCCGQIFNPSYLQDDSIIYKWLDMLLTSKNEKIYQLARDTVVLLLESNPDIGQLLEWVIDRCYTSTPREADACFLALASIFSAKEYPCDHYTSVITVTLLMTGCPRVEVHATALQLLQILDKRFFGSVVGTLHSDSDKEDDKVGTLDVLLSSAYCRSQRFLSKQLAQLRPELTMSIFSEITHRFQSAREDVRALLLQCLLPWLQNMELVATSVPPATPLSYIMYFPDSGTRGRREGTGSTEATEMILNNLFYITAKFSDAHPRDIEELWGTLCQFWPNNLKVILRYLVIMSGMAPTELLPYAKRVALYLVRSCPDRLLDELMAELQTVETLNCLIERTETPPFYRLTSMRKASSHSADGQAAGGINDSRIQDLAVEKGTIHTKRHSGEDPMKIGTCKSDSGIRAYTQAAAAAAAAAVTPGSSGNRPPRGADKIRAASGPSILPRPEDILINDPELRQEENVELRGTSDAAPNGHPHPLPMPEYGGYFAPLTEFLPDVSLPISGFHRCNVAVMLLTDIVVDGIPGIDWTLHLPLMLHILFLGLDHTRIIVREHCKQLCVNLLIVLAEHNDHLTVARILLNSETSKLDLGLTVPALPVIDNNFTELHQQFDSYLLHVSPQAAAYALQHNLSSSTIIAAHHQNLSQTPQSQQQTGSQNGQTTTPPGLTATPAALQINPNNSENSEVPLIHPDEHAPPQPGPSMPIAHVIKSLLKFLAQDTCQPLWNYEDITAKVWAVKSAEQLSCFLKHMVKVFADSYPQARIAERWAQTALQLGLSCSSRHYAGRCLQIFRALNVPINSRMLSDILSRLVETVAEQGEDMQGYVTELLLTLEAAVDSLDSDFRPLDVMKDIFKSTPNLNNKDGGPNSILPGKKSPSGMTPQSSNYSIPSHGRSTSYSVSYCGRKANNSPCDKQVELRNRSSGIDLERSVVCKFGVGGGGAGSALSRSRSAQSLKMLGDTATQDDKMTILAQLFWLSVSLLESDYEHEFMLALRLLTRVLHRLPLDRPDARDKVEKLQQQLKWTAYPGVHALLLKGCTHSATYEPTITLLSQFAPLLTLPVCDPTQSCAFPMNVIALLPYMLLHYEDANEICIRSAENIAQVSTELGAKLENLGTVMTLYSRKTFCKESFQWTKCVVKYLHDTYAHMGLHMVAFLIEVLEKGPQQVQVPVLNVIHCMLHYVDLSAPQAQSINADLLRAIGKYLDTAYWKDSLKILKLIVTRSSSLQVVPPSDGSSAGLSFSFYGAYPDSDMFCKKELAGRTMEFTFDVSQTPLIGRRILLKTEEPVAGGAVSTTGSSSLNSTLTNATTVTVAPSAAQQQTNVQMQQQRANTNVAALAAAAAAQHQQQQHAIGAGSSVVGTPNSPRRSASLSPADTVPLSGWKRPWMSQCRVRECLVNLLTTCGQRVGLPKSPSVIFSQSSDLMERQSSAASSTEETSGPQGDLSSGSRRDDGQPDFTVFKDFDFLEYEDSIAGESTDNFNWGVRRHQLFEGDEDRLNCGSGIGGSIKGGHSSAFEDSFSDKTPILSKRKRQIADDSSDEEAESESPLDEDHRQSFLKSGYSAVPPTSLSLRERRRRNSVSRSDTSGSSAGDLGDLTPCNASPHLPGIIRFSAAIHDEAEENWRRQVQALLVNQPSAHTSELLQQLYRLIKELTFKTVNISKEAKKFFTGIGSQLGNRISLFTDLLSSRADPPQVWCSELQATSPKLFETLRFNVLEVQEHLETFFDRKDQVLECLDAVKTSCKLSLFNEADVAASGLELPSTSSIVYMPFDPASTEVVLDLGRSLYKLMFQLLLLIESNHKISSNVVNHFRMNEDMHDISDLYALVRDALVRYISEAELDCLESSTSTEGEHTPTPSPGLPMTPEEFEAVLTEHIDLQRWPSAIAHVRQYRRISTLNASGYQNVTIFSYNSADNRQKWDEISVILNAYAHGIMKDRTEAFIVSKSDSEVFEIYAILSENLYQVSSALTNMEISMKSYSAGSASGNSHRSEQDIVTNL", "length": 3479 }, "evidence": [ { "id": "RGD:1307034", "url": "https://alliancegenome.org/gene/RGD:1307034#orthology", "database": "AGR" }, { "id": "MGI:2443895", "url": "https://alliancegenome.org/gene/MGI:2443895#orthology", "database": "AGR" }, { "id": "HGNC:20367", "url": "https://alliancegenome.org/gene/HGNC:20367#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060510-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060510-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0016081", "url": "https://alliancegenome.org/gene/FB:FBgn0016081#orthology", "database": "AGR" }, { "id": "SGD:S000001391", "url": "https://alliancegenome.org/gene/SGD:S000001391#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NYQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1279, "end_pos": 1281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1423, "end_pos": 1425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1514, "end_pos": 1516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1731, "end_pos": 1733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1748, "end_pos": 1750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2036, "end_pos": 2038, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2138, "end_pos": 2140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2332, "end_pos": 2334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2570, "end_pos": 2572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2909, "end_pos": 2911, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 854, "end_pos": 856, "annotation": "n_glycosylation_sequon" }, { "start_pos": 980, "end_pos": 982, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9NYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0" }, { "id": "PF14228", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cell morphogenesis central region", "eco_id": "ECO_0000259", "start_pos": 1238, "end_pos": 1398, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9NYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0" }, { "id": "PF14225", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cell morphogenesis protein C-terminal", "eco_id": "ECO_0000259", "start_pos": 2068, "end_pos": 2320, "start_aa": "Ala", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9NYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0" }, { "id": "PF14222", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cell morphogenesis protein N-terminal", "eco_id": "ECO_0000259", "start_pos": 195, "end_pos": 727, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9NYQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYQ0" }, { "id": "PF19421", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19421" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein furry C-terminal", "eco_id": "ECO_0000259", "start_pos": 2346, "end_pos": 3060, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 1279, "end_pos": 1281 }, { "start_pos": 1423, "end_pos": 1425 }, { "start_pos": 1514, "end_pos": 1516 }, { "start_pos": 1731, "end_pos": 1733 }, { "start_pos": 1748, "end_pos": 1750 }, { "start_pos": 2036, "end_pos": 2038 }, { "start_pos": 2138, "end_pos": 2140 }, { "start_pos": 2332, "end_pos": 2334 }, { "start_pos": 2570, "end_pos": 2572 }, { "start_pos": 2909, "end_pos": 2911 }, { "start_pos": 734, "end_pos": 736 }, { "start_pos": 854, "end_pos": 856 }, { "start_pos": 980, "end_pos": 982 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P2Z5-1", "uniprot_ac": "A0A8M9P2Z5", "uniprot_id": "A0A8M9P2Z5_DANRE", "mass": { "chemical_mass": 106901.0, "monoisotopic_mass": 106901.0 }, "refseq": { "ac": "XP_068071768", "name": "transcriptional protein SWT1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071768" }, "gene_names": [ { "name": "swt1", "type": "recommended", "evidence": [ { "id": "A0A8M9P2Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z5" } ] }, { "name": "swt1", "type": "synonym", "evidence": [ { "id": "XP_068071768", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071768" } ] } ], "protein_names": [ { "name": "Transcriptional protein SWT1", "type": "recommended", "evidence": [ { "id": "A0A8M9P2Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z5/entry#names_and_taxonomy" } ] }, { "name": "transcriptional protein SWT1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_068071768", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071768" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068071768", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071768" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "swt1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041015-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041015-373", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd18727", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18727", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "559432", "url": "https://www.ncbi.nlm.nih.gov/gene/559432", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002716", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002716", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:559432", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559432", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M3ATD3", "url": "https://www.orthodb.org/?gene=A0A8M3ATD3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z2T3", "url": "https://www.orthodb.org/?gene=A0A8M6Z2T3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P2Z5", "url": "https://www.orthodb.org/?gene=A0A8M9P2Z5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16161", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16161", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16161:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16161:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13638", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13638", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_068071768", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071768", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3ATD3", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ATD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3ATD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ATD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2T3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P2Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P2Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I5V9", "url": "https://www.uniprot.org/uniprotkb/A0AC58I5V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I5V9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I5V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041015-373", "url": "https://zfin.org/ZDB-GENE-041015-373", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASKKSKKKKNKKEEKLSSRLYEDEKEERDTKRCISSKSKHKHHHCVSFDKDEAKGRRATVSLPEKTFEAILNQTDAGESKSKKKRSKINKNKGTEKSKPVLNLPNKHEKKCVNAKDKHKNASPQISKNKAKNQPSSEEASKKREKLVSRKPPSEDLRWTLAKDDCLKLQQRRMKPVKRRLSQELHAQPKRRNIKNGTDVAQTNCQFKSPTEMRKKLVGKRSKKINQPAGAILQNSPGKTMKNNSKAAMSAVKHVRSKLKLLEDISPKKKDRAKQRKTLGVLLGEKSPSFCGSIANTKFKIPKLPSAVKAQTNTNLFNVNSSDSRTQITTQPSLPGSSPAKPQNFLLRQQMQKPEEVSSQTSYELSSLCSSHHSYVSRQVQLVYTDDKGEVTMTDGASHNDQHISSQKAPKTYDFDHEVHLVEELNLARSERRLEVNVEQNCGELTCMDIDPPEEGANTILKKQALLIVLDTNVLLSHLEFVKKIRSRGFGGLGFPTLLIPWVVLQELDYLKSGKLSSKVEDKARPAVHYIYSCLKNQEPRLIGQSMQLASQADCGPGVVNNDDRVLQCCLQYQALYPEGALVLCTNDKNLCSKALLSGVKAYSKADLVIEAEGTTSKIFEPDQQYICARPAVMSPAGPVEKAEKQGSQDNSNSIVVDEQDLIEYVSLLESSLQAALSEVLTEEMKAAYGDLWIEIVYVKPPWSLEGLLKCFKKHWIAVFGLIINRSLLSCVEMLSDCLCSDRSVEHTSILSAVSLAKELLSALSGRSQYSGHVAHALSTLHTLQQRLQSPKALLESGEADNEDSLMAEIEDDVALPPSTSHQEVWALFESIWNNVCQISSSLFSALHYTPGTTEPSLRSTSPPPQEALSCLQRLSTALKQLLEALQRLLSADSSVQDAQSLLSFIQTSEIAAMEPRFTAKSLFDCVSQQEYREKLCVGGAQLSELCVNLDQCAAAARSWP", "length": 961, "header": "tr|A0A8M9P2Z5-1|A0A8M9P2Z5_DANRE Isoform 1 of Transcriptional protein SWT1 OS=Danio rerio OX=7955 GN=swt1 PE=3 SV=1 CANONICAL=A0A8M9P2Z5-1" }, "isoforms": [ { "isoform_ac": "A0A8M3ATD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z5/entry#A0A8M3ATD3-1", "sequence": { "sequence": "MASKKSKKKKNKKEEKLSSRLYEDEKEERDTKRCISSKSKHKHHHCVSFDKDEAKGRRATVSLPEKTFEAILNQTDAGESKSKKKRSKINKNKGTEKSKPVLNLPNKHEKKCVNAKDKHKNASPQISKNKAKNQPSSEEASKKREKLVSRKPPSEDLRWTLAKDDCLKLQQRRMKPVKRRLSQELHAQPKRRNIKNGTDVAQTNCQFKSPTEMRKKLVGKRSKKINQPAGAILQNSPGKTMKNNSKAAMSAVKHVRSKLKLLEDISPKKKDRAKQRKTLGVLLGEKSPSFCGSIANTKFKIPKLPSAVKAQTNTNLFNVNSSDSRTQITTQPSLPGSSPAKPQNFLLRQQMQKPEEVSSQTSYELSSLCSSHHSYVSRQVQLVYTDDKGEVTMTDGASHNDQHISSQKAPKTYDFDHEVHLVEELNLARSERRLEVNVEQNCGELTCMDIDPPEEGANTILKKQALLIVLDTNVLLSHLEFVKKIRSRGFGGLGFPTLLIPWVVLQELDYLKSGKLSSKVEDKARPAVHYIYSCLKNQEPRLIGQSMQLASQADCGPGVVNNDDRVLQCCLQYQALYPEGALVLCTNDKNLCSKALLSGVKAYSKADLVIEAEGTTSKIFEPDQQYICARPAVMSPAGPVEKEKQGSQDNSNSIVVDEQDLIEYVSLLESSLQAALSEVLTEEMKAAYGDLWIEIVYVKPPWSLEGLLKCFKKHWIAVFGLIINRSLLSCVEMLSDCLCSDRSVEHTSILSAVSLAKELLSALSGRSQYSGHVAHALSTLHTLQQRLQSPKALLESGEADNEDSLMAEIEDDVALPPSTSHQEVWALFESIWNNVCQISSSLFSALHYTPGTTEPSLRSTSPPPQEALSCLQRLSTALKQLLEALQRLLSADSSVQDAQSLLSFIQTSEIAAMEPRFTAKSLFDCVSQQEYREKLCVGGAQLSELCVNLDQCAAAARSWP", "length": 960, "header": "tr|A0A8M3ATD3-1|A0A8M9P2Z5_DANRE Computationally mapped isoform of Transcriptional protein SWT1 OS=Danio rerio OX=7955 GN=swt1 PE=3 SV=1 CANONICAL=A0A8M9P2Z5-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z2T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z5/entry#A0A8M6Z2T3-1", "sequence": { "sequence": "MASKKSKKKKNKKEEKLSSRLYEDEKEERDTKRCISSKSKHKHHHCVSFDKDEAKGRRATVSLPEKTFEAILNQTDAGESKSKKKRSKINKNKGTEKSKPVLNLPNKHEKKCVNAKDKHKNASPQISKNKAKNQPSSEEASKKREKLVSRKPPSEDLRWTLAKDDCLKLQQRRMKPVKRRLSQELHAQPKRRNIKNGTDVAQTNCQFKSPTEMRKKLVGKRSKKINQPAGAILQNSPGKTMKNNSKAAMSAVKHVRSKLKLLEDISPKKKDRAKQRKTLGVLLGEKSPSFCGSIANTKFKIPKLPSAVKAQTNTNLFNVNSSDSRTQITTQPSLPGSSPAKPQNFLLRQQMQKPEEVSSQTSYELSSLCSSHHSYVSRQVQLVYTDDKGEVTMTDGASHNDQHISSQKAPKTYDFDHEVHLVEELNLARSERRLEVNVEQNCGELTCMDIDPPEEEKQALLIVLDTNVLLSHLEFVKKIRSRGFGGLGFPTLLIPWVVLQELDYLKSGKLSSKVEDKARPAVHYIYSCLKNQEPRLIGQSMQLASQADCGPGVVNNDDRVLQCCLQYQALYPEGALVLCTNDKNLCSKALLSGVKAYSKADLVIEAEGTTSKIFEPDQQYICARPAVMSPAGPVEKAEKQGSQDNSNSIVVDEQDLIEYVSLLESSLQAALSEVLTEEMKAAYGDLWIEIVYVKPPWSLEGLLKCFKKHWIAVFGLIINRSLLSCVEMLSDCLCSDRSVEHTSILSAVSLAKELLSALSGRSQYSGHVAHALSTLHTLQQRLQSPKALLESGEADNEDSLMAEIEDDVALPPSTSHQEVWALFESIWNNVCQISSSLFSALHYTPGTTEPSLRSTSPPPQEALSCLQRLSTALKQLLEALQRLLSADSSVQDAQSLLSFIQTSEIAAMEPRFTAKSLFDCVSQQEYREKLCVGGAQLSELCVNLDQCAAAARSWP", "length": 955, "header": "tr|A0A8M6Z2T3-1|A0A8M6Z2T3_DANRE Computationally mapped isoform of Transcriptional protein SWT1 OS=Danio rerio OX=7955 GN=swt1 PE=3 SV=1 CANONICAL=A0A8M9P2Z5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P2Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z5/entry#A0A8M9P2Z5-1", "sequence": { "sequence": "MASKKSKKKKNKKEEKLSSRLYEDEKEERDTKRCISSKSKHKHHHCVSFDKDEAKGRRATVSLPEKTFEAILNQTDAGESKSKKKRSKINKNKGTEKSKPVLNLPNKHEKKCVNAKDKHKNASPQISKNKAKNQPSSEEASKKREKLVSRKPPSEDLRWTLAKDDCLKLQQRRMKPVKRRLSQELHAQPKRRNIKNGTDVAQTNCQFKSPTEMRKKLVGKRSKKINQPAGAILQNSPGKTMKNNSKAAMSAVKHVRSKLKLLEDISPKKKDRAKQRKTLGVLLGEKSPSFCGSIANTKFKIPKLPSAVKAQTNTNLFNVNSSDSRTQITTQPSLPGSSPAKPQNFLLRQQMQKPEEVSSQTSYELSSLCSSHHSYVSRQVQLVYTDDKGEVTMTDGASHNDQHISSQKAPKTYDFDHEVHLVEELNLARSERRLEVNVEQNCGELTCMDIDPPEEGANTILKKQALLIVLDTNVLLSHLEFVKKIRSRGFGGLGFPTLLIPWVVLQELDYLKSGKLSSKVEDKARPAVHYIYSCLKNQEPRLIGQSMQLASQADCGPGVVNNDDRVLQCCLQYQALYPEGALVLCTNDKNLCSKALLSGVKAYSKADLVIEAEGTTSKIFEPDQQYICARPAVMSPAGPVEKAEKQGSQDNSNSIVVDEQDLIEYVSLLESSLQAALSEVLTEEMKAAYGDLWIEIVYVKPPWSLEGLLKCFKKHWIAVFGLIINRSLLSCVEMLSDCLCSDRSVEHTSILSAVSLAKELLSALSGRSQYSGHVAHALSTLHTLQQRLQSPKALLESGEADNEDSLMAEIEDDVALPPSTSHQEVWALFESIWNNVCQISSSLFSALHYTPGTTEPSLRSTSPPPQEALSCLQRLSTALKQLLEALQRLLSADSSVQDAQSLLSFIQTSEIAAMEPRFTAKSLFDCVSQQEYREKLCVGGAQLSELCVNLDQCAAAARSWP", "length": 961, "header": "tr|A0A8M9P2Z5-1|A0A8M9P2Z5_DANRE Isoform 1 of Transcriptional protein SWT1 OS=Danio rerio OX=7955 GN=swt1 PE=3 SV=1 CANONICAL=A0A8M9P2Z5-1" }, "locus": {} }, { "isoform_ac": "A0AC58I5V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z5/entry#A0AC58I5V9-1", "sequence": { "sequence": "MASKKSKKKKNKKEEKLSSRLYEDEKEERDTKRCISSKSKHKHHHCVSFDKDEAKGRRATVSLPEKTFEAILNQTDAGESKSKKKRSKINKNKGTEKSKPVLNLPNKHEKKCVNAKDKHKNASPQISKNKAKNQPSSEEASKKREKLVSRKPPSEDLRWTLAKDDCLKLQQRRMKPVKRRLSQELHAQPKRRNIKNGTDVAQTNCQFKSPTEMRKKLVGKRSKKINQPAGAILQNSPGKTMKNNSKAAMSAVKHVRSKLKLLEDISPKKKDRAKQRKTLGVLLGEKSPSFCGSIANTKFKIPKLPSAVKAQTNTNLFNVNSSDSRTQITTQPSLPGSSPAKPQNFLLRQQMQKPEEVSSQTSYELSSLCSSHHSYVSRQVQLVYTDDKGEVTMTDGASHNDQHISSQKAPKTYDFDHEVHLVEELNLARSERRLEVNVEQNCGELTCMDIDPPEEEKQALLIVLDTNVLLSHLEFVKKIRSRGFGGLGFPTLLIPWVVLQELDYLKSGKLSSKVEDKARPAVHYIYSCLKNQEPRLIGQSMQLASQADCGPGVVNNDDRVLQCCLQYQALYPEGALVLCTNDKNLCSKALLSGVKAYSKADLVIEAEGTTSKIFEPDQQYICARPAVMSPAGPVEKEKQGSQDNSNSIVVDEQDLIEYVSLLESSLQAALSEVLTEEMKAAYGDLWIEIVYVKPPWSLEGLLKCFKKHWIAVFGLIINRSLLSCVEMLSDCLCSDRSVEHTSILSAVSLAKELLSALSGRSQYSGHVAHALSTLHTLQQRLQSPKALLESGEADNEDSLMAEIEDDVALPPSTSHQEVWALFESIWNNVCQISSSLFSALHYTPGTTEPSLRSTSPPPQEALSCLQRLSTALKQLLEALQRLLSADSSVQDAQSLLSFIQTSEIAAMEPRFTAKSLFDCVSQQEYREKLCVGGAQLSELCVNLDQCAAAARSWP", "length": 954, "header": "tr|A0AC58I5V9-1|A0AC58I5V9_DANRE Computationally mapped isoform of Transcriptional protein SWT1 OS=Danio rerio OX=7955 GN=swt1 PE=3 SV=1 CANONICAL=A0A8M9P2Z5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:559432", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559432", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZHR0-1", "protein_name": "Transcriptional protein SWT1", "gene_name": "Swt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLCTTSAHKLETVYDHKFPKMSIKESCGKEEKSQKKQTTSSPTFDEDKKEGEISAGSTSSEHCVKPVSTKKRKLKPDDTDIVYYNTNRKHSMKRLNVEVGLPKKRPKFSSSTQVASYLNSNQITLHSSSSDGAKDTKLKDCKLTNIGSKLDYEIKSRSLIKITKDMKSKAEDQTKEKNWPSLLIQKKMKELKKEKNNKDSSEELEKCTKNQPPQNYNFSNIIKEPLESGRKKISFKIPKKSSSALQKLAEENIFSVDSSKSKSKQEGKEHLQSHRVSLSLERHKTENLFSESTHKHTVCERRREYHLEHQETNGSDSKENCAQSFETPCSSVSSETIQDTDEEMQIVEELHAARVGKSVDLPAGPPSGELMSMEIDLVEDDVHSSADILSNTASDKKLLIVIDTNILMNHLKFVRILKTTEIPGFDTLVLIIPWVVMQELDRMKAGKLLKHVQHKAVPAIHFINDSLKSQDRKLWGQSLQLASQKLYGLSDENNDDRVLKCCLQYQELFPCSLVILCTDDRNLRSKGLISGVKSLSKEELDTEILNLTLNTDLCHQPYISKQQLKAEVPPTEETSKEESTNSGLSILLERIICDLEKCLGTALSSILETEMKIAFGNLWMEVLYLKPPWTLINLLQCFKKHWLAVFGLVMENNLLVTIESLYDNLSKANKAVDFTTVKFLLQDSKSLLHAFSTRSNYDGILPQTFAQVNKLLQVLAEVKTKLKPNSSESTMSKKQEDTLMKLHNQEVTVFLDSHPPQFTRHQEIWSVLENVWTSIYQNSTDVFQTLDSSSTLTTSKIASFEEAFIYLQKLMVAVKDILEGIQRILAPNSNCQDVETLYNFLIKYEVNKNVRFTAQELYDCVSQTEYREKLTIGCRQLIEMEYTMQQCSASVYMEAASRGWCEGMLNSRT", "length": 910 }, "evidence": [ { "id": "RGD:1308695", "url": "https://alliancegenome.org/gene/RGD:1308695#orthology", "database": "AGR" }, { "id": "MGI:1914125", "url": "https://alliancegenome.org/gene/MGI:1914125#orthology", "database": "AGR" }, { "id": "HGNC:16785", "url": "https://alliancegenome.org/gene/HGNC:16785#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041015-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041015-373#orthology", "database": "AGR" }, { "id": "FB:FBgn0030892", "url": "https://alliancegenome.org/gene/FB:FBgn0030892#orthology", "database": "AGR" }, { "id": "SGD:S000005692", "url": "https://alliancegenome.org/gene/SGD:S000005692#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12104-1", "protein_name": "Transcriptional protein SWT1", "gene_name": "SWT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTDEKRAFPKGNNHIRSETFNGSVSHKISESIKDIASLRPHGKYTVQDIDNIIASTSSHENRGQSGDSNGCINHDEEGDIPMCDLNDESDVEMISEYLSSQREMEAQSVANYMPKINDDLPLLNPPTLKTAFVVDTNFIISHLNTLEKLRSLSSTYHHLIIVPTTVIQELDGLKKSPDIARDNDDTTNQEHDRTIGTLARWGNDWIYKNLANLDSGLIGQKLKQSLNPGSLKDDSILDCCLYFKEILNCFVILLSNDKNLCTKALTEDILTVSFRKNMDAKIIAMRAYEENQLRFANLRDSTVNNFDQNVTSYAHIPGIETPPLQFDKVSQNVFEQVKETIFFAIDHTLRKEYGEDIGFIDYNPDKLTTIENASNYIYLFWVSVFSELFTCSKIKKNEWKSLPTVLKSKPTNLNDLRTFEQFWETVLHFLFSKFTNEEKQSLEKQIHEWKTSINAIST", "length": 458 }, "evidence": [ { "id": "RGD:1308695", "url": "https://alliancegenome.org/gene/RGD:1308695#orthology", "database": "AGR" }, { "id": "MGI:1914125", "url": "https://alliancegenome.org/gene/MGI:1914125#orthology", "database": "AGR" }, { "id": "HGNC:16785", "url": "https://alliancegenome.org/gene/HGNC:16785#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041015-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041015-373#orthology", "database": "AGR" }, { "id": "FB:FBgn0030892", "url": "https://alliancegenome.org/gene/FB:FBgn0030892#orthology", "database": "AGR" }, { "id": "SGD:S000005692", "url": "https://alliancegenome.org/gene/SGD:S000005692#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5T5J6-1", "protein_name": "Transcriptional protein SWT1", "gene_name": "SWT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSKESCGKKETSQRKDTTTSSPNFGEKDKKERKTPASSTSSSSIRSVSSEKRKLKSDHTDVLYYNIKRRQGLKRLSVEIDTLRRRPKIGSSSQRPIKLKEASYSNDNQIILQSPSSNGTKKDIHKCVDFKPKDIKLTNAGSKLDHGIKSLSSPKIASDVKPKAEGQASENKWSHLLVQREKMKELKKGRNSKFRDNSEKCVLEKWKRNQFSQDYNSNKIIKEPLGSRRQKISFKIPIKSRDTLQKLVEENVFNIDSNNSKTKQEEREYLESSQVSLNVTRQKTEHLLSDFTYKRTVHEWKRKHHYDHQESNDSHSRENLTQSFEAPCCSVSSESIQDADQEMQIVEELHAARVGKSVDLPGELMSMEIDLEDDVHSSSANNTSDRKLLIVIDTNILMNHLKFVRILKTTEVPGFDKLVLIIPWVVMQELDRMKEGKLLKRAQHKAIPAVHFINDSLKNQDRKLWGQSIQLASQKHYGLSDENNDDRVLKCCLQHQELFPCSFVILCTDDRNLRNKGLISGVKSLSKEELSAELLHLSLNTDVCHQPCIPKQQLKAETTPLKESYKEESTNSGLSILLESIVSDLEKSLGTGLSSILETEMKIAFGNLWMEILYLKPPWTLLHLLQCFKKHWLAVFGLVMEKNLLLTIESLYKNLRKANKAVDFTTVKFLLQDSRSLLHAFSTRSNYDGILPQTFAQVNNLLQTFAEVKTKLKPNSSENTVTKKQEGTSLKNSHNQEITVFSSSHLPQPSRHQEIWSILESVWITIYQNSTDVFQRLGSNSALTTSNIASFEEAFICLQKLMAAVRDILEGIQRILAPNSNYQDVETLYNFLIKYEVNKNVKFTAQEIYDCVSQTEYREKLTIGCRQLVEMEYTMQQCNASVYMEAKNRGWCEDMLNYRI", "length": 900 }, "evidence": [ { "id": "RGD:1308695", "url": "https://alliancegenome.org/gene/RGD:1308695#orthology", "database": "AGR" }, { "id": "MGI:1914125", "url": "https://alliancegenome.org/gene/MGI:1914125#orthology", "database": "AGR" }, { "id": "HGNC:16785", "url": "https://alliancegenome.org/gene/HGNC:16785#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041015-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041015-373#orthology", "database": "AGR" }, { "id": "FB:FBgn0030892", "url": "https://alliancegenome.org/gene/FB:FBgn0030892#orthology", "database": "AGR" }, { "id": "SGD:S000005692", "url": "https://alliancegenome.org/gene/SGD:S000005692#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7KUW4-1", "protein_name": "Swt1 RNA endoribonuclease, isoform B", "gene_name": "Swt1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLGGESKHTPKSSNLRPLDDDQLVRIISTPRPSNGVSQHPAQDRLKRLQGQLKRVQDNEKEQGTTKRITHSSSASRRSSASTSTPQRLLKFPPKVAMNAWEKPKALVDANRLKAGRTQTAYQRLMLLRASLQQKQLYEERNNNIVAKINEEVIEKQPEACNITNPSAFDGSTASDMEVEPMEWQESIEEEAAQNDQDEAKKGDDTLLMLPAESIEEEAPQKGQDEAKEEDDTILMLQAADAEELPPRLEDYMYFVLDTNVLIHNHKFVERLTDVVLPGTVGSMLYLPYIVIKELDKLKSKYQSDCLQRVIAMRAIRFLNTKFDESFQIQAQSALEEADHLIKIDCPDDSILNCCLQLQAQVPHMILLTNDANLRLKANASNIQVSCRSDLMSTYVDEFAGFGD", "length": 404 }, "evidence": [ { "id": "RGD:1308695", "url": "https://alliancegenome.org/gene/RGD:1308695#orthology", "database": "AGR" }, { "id": "MGI:1914125", "url": "https://alliancegenome.org/gene/MGI:1914125#orthology", "database": "AGR" }, { "id": "HGNC:16785", "url": "https://alliancegenome.org/gene/HGNC:16785#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041015-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041015-373#orthology", "database": "AGR" }, { "id": "FB:FBgn0030892", "url": "https://alliancegenome.org/gene/FB:FBgn0030892#orthology", "database": "AGR" }, { "id": "SGD:S000005692", "url": "https://alliancegenome.org/gene/SGD:S000005692#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9DBQ9-1", "protein_name": "Transcriptional protein SWT1", "gene_name": "Swt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLCTTSAHKLETVYDHKFLKMSIKESCAKEEKSQKKQTISSPTFNEDKKKGEISAGSTSSEHGVQPVSTKKRKLKADDTDNVYYNANRKNSKRLNVEVFIPKKRLKFSSSTQAVSYLNNNQMTSHSCSSNGTKDTKVKDCKLTNIGSKLNYEIKNHSRIKITKDMKSKPVDQTKEKNWPSLLIQKKMKELKKEKNNKDSSEELEKCKKNHLPQNYNFSNMIKESFESGRKKISFKIPKKSSTTLQKLVEEKIFTIDSSKSKSKQEEKQHLQSHQMSLNLARHKTENSFSDSTHKQSVCERIRKDHCEHQGTSSSDSKENHAQSFETPCSSVSSEDTQDADEEMQIVEELHAARVGRSVDLPVVPPSGELMSMEIDLVDEDAHPSAAHTASDTKLLIVMDTNVLMNHLKFVKILKTTEIPGFDTLVLIIPWVVIQELDRMKAGKLLKHVQHKAVPAIHFINNSLKSQDRKLWGQSLQLASQKLYGLSDENNDDRVLKCCLQYQQLFPCSLVILCTDDRNLRTKGLISGVKSLSKEDLDTEILNLTLNTDLCHQPCISKQQLNAEVPPAKETPKEGAANSGLSILLERIICDLEKCLGTALSSILETEMKIAFGNLWMEVLYLKPPWTLINLLQCFKKHWLAVFGLVMENNLLVTVESLYENLCKANKAVDFTTVKFLLQDSKSLLHAFSTRSNYDGVLPQTFAQVNKLLQVLAEVKTKLKPSSSESTRSKEQEDTSLVKLHNQDVNVFLDSNLPQATRHQEIWSVLESVWMSIYQNSTDVFQTLDSSSTLTTSKIASFEEAFVYLQKLMVAVKDILEGIQRILAPNSNYQDVETLYNFLIKYEVNKNVKFTARELYDCVSQTEYRERLTIGCRQLIEMECTMQQCSASVYMEARSRGWCEDMLNNRP", "length": 907 }, "evidence": [ { "id": "RGD:1308695", "url": "https://alliancegenome.org/gene/RGD:1308695#orthology", "database": "AGR" }, { "id": "MGI:1914125", "url": "https://alliancegenome.org/gene/MGI:1914125#orthology", "database": "AGR" }, { "id": "HGNC:16785", "url": "https://alliancegenome.org/gene/HGNC:16785#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041015-373", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041015-373#orthology", "database": "AGR" }, { "id": "FB:FBgn0030892", "url": "https://alliancegenome.org/gene/FB:FBgn0030892#orthology", "database": "AGR" }, { "id": "SGD:S000005692", "url": "https://alliancegenome.org/gene/SGD:S000005692#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2Z5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 725, "end_pos": 727, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P2Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z5" }, { "id": "SM00670", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00670" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PIN", "eco_id": "ECO_0000259", "start_pos": 466, "end_pos": 593, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 725, "end_pos": 727 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z7G3-1", "uniprot_ac": "A0A8M6Z7G3", "uniprot_id": "A0A8M6Z7G3_DANRE", "mass": { "chemical_mass": 182693.0, "monoisotopic_mass": 182693.0 }, "refseq": { "ac": "XP_009301915", "name": "myomesin-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301915" }, "gene_names": [ { "name": "myom1b", "type": "recommended", "evidence": [ { "id": "A0A8M6Z7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3" } ] }, { "name": "myom1b", "type": "synonym", "evidence": [ { "id": "XP_009301915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301915" } ] } ], "protein_names": [ { "name": "Myomesin-1", "type": "recommended", "evidence": [ { "id": "A0A8M6Z7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3/entry#names_and_taxonomy" } ] }, { "name": "Myomesin family member 1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3/entry#names_and_taxonomy" } ] }, { "name": "myomesin-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_009301915", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301915" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009301915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301915" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7G3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "myom1b", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080416-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080416-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20951", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20951", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100144770", "url": "https://www.ncbi.nlm.nih.gov/gene/100144770", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060200", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060200", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100144770", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100144770", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M3AUQ5", "url": "https://www.orthodb.org/?gene=A0A8M3AUQ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AUS9", "url": "https://www.orthodb.org/?gene=A0A8M3AUS9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3B4K5", "url": "https://www.orthodb.org/?gene=A0A8M3B4K5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3BBG1", "url": "https://www.orthodb.org/?gene=A0A8M3BBG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z0A9", "url": "https://www.orthodb.org/?gene=A0A8M6Z0A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z7G3", "url": "https://www.orthodb.org/?gene=A0A8M6Z7G3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13817", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13817", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13817:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13817:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28321", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28321", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009301915", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301915", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3AUQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AUQ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AUQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AUQ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AUS9", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AUS9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AUS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AUS9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B4K5", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B4K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B4K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B4K5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3BBG1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BBG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3BBG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BBG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z0A9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z0A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z7G3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z7G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G1Q2", "url": "https://www.uniprot.org/uniprotkb/A0AC58G1Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G1Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G1Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G1R3", "url": "https://www.uniprot.org/uniprotkb/A0AC58G1R3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G1R3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G1R3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G1R4", "url": "https://www.uniprot.org/uniprotkb/A0AC58G1R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G1R4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G1R4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G1Y8", "url": "https://www.uniprot.org/uniprotkb/A0AC58G1Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G1Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G1Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080416-2", "url": "https://zfin.org/ZDB-GENE-080416-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSGSIPFYQKHHRHYDRSYRSRETESAISQYQQSSSSYSAHSSKSSKGIRAATYTALDEGLSPLPKRAKPTYLAMDKENQIIGYVVPIFRGSHDFASGLSDSEEARAKVSAGYVSGRELFSSGVESERSRRTVMRESAERIQLSKRIHENEEYHKRQNEDSLMHTPEFVIKPRSHTVWEKQCVRLHCTISGWPDPRVVWYKNNVSIDPMSNPGKYKVESSYNVHSLEINRCDFDDTAQYRVSAMNSKGENSAYASVVVKRFKGEFDESLPSPRLQSRKFGFQAPCLEYGVTFETHIVEKFGVAFGREGETLSFGCSVIIYPSLQRFQPEIEWYRDDKLLVPSKWVQMHWSGDRATLTLTHLNKEDEGLYTLRVITKSGFQSHSAYVFVRDADADVAGAPGAPLDVHCLDANKDYVIVAWKQPAVDGGSAILGYFVDRCEVGTTHWAQCNDTPVKFARFPVTGLIEGRSYTFRVRAVNKAGMSHPSRVSEPVAAMDPADRSRKGASAPWTGQIIVTEEEPVEGVVPGRPQELSVIEATKNYVVLSWKPPGEKGHEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYRFRVRCCNSAGVGEPSEPTDATTVGDKLDIPSAPGRVVPTRNTDTSVVISWEASRDAKELVGYYIESSIAGSNTWEPCNNKPVKATRFICHGLTTGESYVFRVRAVNAAGISEFSQESEAIVVKAAIGGGVLHASPAPPYGISVLECVRDSMVLAWKQPTFIGGADITGYFVDYREVTGGVPGKWHEANIKAISERAYRVSELKENMLYQFQVRAANMAGVGIPSLPSETFKCEEWTIAVPGPPHDLQVQEVRKNSLVLLWKPPVYQGRDAVNGYYIDIKEAEADFEMWRGVNEKATDKAFFKVNDLKGGESYVFRVRAQNKAGVGKASDPTEPVEAVTKPGTAEIVVNVDDEGVISLNFECSNLTGDSKFVWSKNYEEMTEPERMTLETKGSKSKAIFNSPSEEDLGIYSCFVTHTDGASASYTFSEEALKELLKVSHDHKFPIIPLKTELAVELLEKGRVRFWLQAAKISANAKVEYVFNDNMISQGEKYKMNFDKNTGIIEMFMESLGKEDEGTFTFQLQDGKATNQSSLVLIGDVFKQLQKESEFQRKEWHRKQGPHFVEYLGYEVTPECCVRLKCKVGNMKKDSTALWYKDGREVKVDEKLDFSEGVLTLEIAQISKKDAGIYEVVLKDERGKDTSTLNLTDQGFKDLMNQVFSVIANSSTPLKIQSTEEGIRLYTFVSYYNDELHVTWHHKDAAIAFTERIKSGVVGEQLWLQISEPTEKDKGKYAIEFFDGKGGLRRTVELAGQAFDDAFAEFQRLKAAAIAERNRARVAGGLPDVVTIQEGKSLNLTCNIWGDPVPEVTWLKNEREMVSDDHYILKFESGKFASFTITSVNTADSGKYSILVKNKYGTESGDFTLNVIESVPDFGVVSYLADAEGNINVGSTMTPVQRKPSSRSFPTTPSTVTSTLTSTPTNANPQNKTTANENQSSSTDPPSPISDNQTTSTPLNPPDQSSGTPVPQNQTSDPPIHSNPQCSSPTEEEEESVDDGKMTAVVEVTVNLGLSPLKADAAEDLTEAVSTPEPETACPTEPENDSEEPTPDPDTAN", "length": 1646, "header": "tr|A0A8M6Z7G3-1|A0A8M6Z7G3_DANRE Isoform 1 of Myomesin-1 OS=Danio rerio OX=7955 GN=myom1b PE=1 SV=1 CANONICAL=A0A8M6Z7G3-1" }, "isoforms": [ { "isoform_ac": "A0A8M3AUQ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3/entry#A0A8M3AUQ5-1", "sequence": { "sequence": "MSGSIPFYQKHHRHYDRSYRSRETESAISQYQQSSSSYSAHSSKSSKGIRAATYTALDEGLSPLPKRAKPTYLAMDKENQIIGYVVPIFRGSHDFASGLSDSEEARAKVSAGYVSGRELFSSGVESERSRRTVMRESAERIQLSKRIHENEEYHKRQNEDSLMHTPEFVIKPRSHTVWEKQCVRLHCTISGWPDPRVVWYKNNVSIDPMSNPGKYKVESSYNVHSLEINRCDFDDTAQYRVSAMNSKGENSAYASVVVKRFKGEFDESLPSPRLQSRKFGFQAPCLEYGVTFETHIVEKFGVAFGREGETLSFGCSVIIYPSLQRFQPEIEWYRDDKLLVPSKWVQMHWSGDRATLTLTHLNKEDEGLYTLRVITKSGFQSHSAYVFVRDADADVAGAPGAPLDVHCLDANKDYVIVAWKQPAVDGGSAILGYFVDRCEVGTTHWAQCNDTPVKFARFPVTGLIEGRSYTFRVRAVNKAGMSHPSRVSEPVAAMDPADRSRKGASAPWTGQIIVTEEEPVEGVVPGRPQELSVIEATKNYVVLSWKPPGEKGHEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYRFRVRCCNSAGVGEPSEPTDATTVGDKLDIPSAPGRVVPTRNTDTSVVISWEASRDAKELVGYYIESSIAGSNTWEPCNNKPVKATRFICHGLTTGESYVFRVRAVNAAGISEFSQESEAIVVKAAIGGGVLHASPAPPYGISVLECVRDSMVLAWKQPTFIGGADITGYFVDYREVTGGVPGKWHEANIKAISERAYRVSELKENMLYQFQVRAANMAGVGIPSLPSETFKCEEWTIAVPGPPHDLQVQEVRKNSLVLLWKPPVYQGRDAVNGYYIDIKEAEADFEMWRGVNEKATDKAFFKVNDLKGGESYVFRVRAQNKAGVGKASDPTEPVEAVTKPGTAEIVVNVDDEGVISLNFECSNLTGDSKFVWSKNYEEMTEPERMTLETKGSKSKAIFNSPSEEDLGIYSCFVTHTDGASASYTFSEEALKELLKVSHDHKFPIIPLKTELAVELLEKGRVRFWLQAAKISANAKVEYVFNDNMISQGEKYKMNFDKNTGIIEMFMESLGKEDEGTFTFQLQDGKATNQSSLVLIGDVFKQLQKESEFQRKEWHRKQGPHFVEYLGYEVTPECCVRLKCKVGNMKKDSTALWYKDGREVKVDEKLDFSEGVLTLEIAQISKKDAGIYEVVLKDERGKDTSTLNLTDQGFKDLMNQVFSVIANSSTPLKIQSTEEGIRLYTFVSYYNDELHVTWHHKDAAIAFTERIKSGVVGEQLWLQISEPTEKDKGKYAIEFFDGKGGLRRTVELAGQAFDDAFAEFQRLKAAAIAERNRARVAGGLPDVVTIQEGKSLNLTCNIWGDPVPEVTWLKNEREMVSDDHYILKFESGKFASFTITSVNTADSGKYSILVKNKYGTESGDFTLNVIESVPDFGVVSYLADAEGNINVGSTMTPVQRKPSSRSFPTTPSTVTSTLTSTPTNANPQNKTTANENQSSSTDPPSPISDNQTTSTPLNPPDQSSGTPVPQNQTSDPPIHSNPQCSSPTEEEEESVDDGKMTAVVEDAAEDLTEAVSTPEPETACPTEPENDSEEPTPDPDTAN", "length": 1634, "header": "tr|A0A8M3AUQ5-1|A0A8M6Z7G3_DANRE Computationally mapped isoform of Myomesin-1 OS=Danio rerio OX=7955 GN=myom1b PE=1 SV=1 CANONICAL=A0A8M6Z7G3-1" }, "locus": {} }, { "isoform_ac": "A0A8M3AUS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3/entry#A0A8M3AUS9-1", "sequence": { "sequence": "MSGSIPFYQKHHRHYDRSYRSRETESAISQYQQSSSSYSAHSSKSSKGIRAATYTALDEGLSPLPKRAKPTYLAMDKENQIIGYVVPIFRGSHDFASGLSDSEEARAKVSAGYVSGRELFSSGVESERSRRTVMRESAERIQLSKRIHENEEYHKRQNEDSLMHTPEFVIKPRSHTVWEKQCVRLHCTISGWPDPRVVWYKNNVSIDPMSNPGKYKVESSYNVHSLEINRCDFDDTAQYRVSAMNSKGENSAYASVVVKRFKGEFDESLPSPRLQSRKFGFQAPCLEYGVTFETHIVEKFGVAFGREGETLSFGCSVIIYPSLQRFQPEIEWYRDDKLLVPSKWVQMHWSGDRATLTLTHLNKEDEGLYTLRVITKSGFQSHSAYVFVRDADADVAGAPGAPLDVHCLDANKDYVIVAWKQPAVDGGSAILGYFVDRCEVGTTHWAQCNDTPVKFARFPVTGLIEGRSYTFRVRAVNKAGMSHPSRVSEPVAAMDPADRSRKGASAPWTGQIIVTEEEPVEGVVPGRPQELSVIEATKNYVVLSWKPPGEKGHEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYRFRVRCCNSAGVGEPSEPTDATTVGDKLDIPSAPGRVVPTRNTDTSVVISWEASRDAKELVGYYIESSIAGSNTWEPCNNKPVKATRFICHGLTTGESYVFRVRAVNAAGISEFSQESEAIVVKAAIASPAPPYGISVLECVRDSMVLAWKQPTFIGGADITGYFVDYREVTGGVPGKWHEANIKAISERAYRVSELKENMLYQFQVRAANMAGVGIPSLPSETFKCEEWTIAVPGPPHDLQVQEVRKNSLVLLWKPPVYQGRDAVNGYYIDIKEAEADFEMWRGVNEKATDKAFFKVNDLKGGESYVFRVRAQNKAGVGKASDPTEPVEAVTKPGTAEIVVNVDDEGVISLNFECSNLTGDSKFVWSKNYEEMTEPERMTLETKGSKSKAIFNSPSEEDLGIYSCFVTHTDGASASYTFSEEALKELLKVSHDHKFPIIPLKTELAVELLEKGRVRFWLQAAKISANAKVEYVFNDNMISQGEKYKMNFDKNTGIIEMFMESLGKEDEGTFTFQLQDGKATNQSSLVLIGDVFKQLQKESEFQRKEWHRKQGPHFVEYLGYEVTPECCVRLKCKVGNMKKDSTALWYKDGREVKVDEKLDFSEGVLTLEIAQISKKDAGIYEVVLKDERGKDTSTLNLTDQGFKDLMNQVFSVIANSSTPLKIQSTEEGIRLYTFVSYYNDELHVTWHHKDAAIAFTERIKSGVVGEQLWLQISEPTEKDKGKYAIEFFDGKGGLRRTVELAGQAFDDAFAEFQRLKAAAIAERNRARVAGGLPDVVTIQEGKSLNLTCNIWGDPVPEVTWLKNEREMVSDDHYILKFESGKFASFTITSVNTADSGKYSILVKNKYGTESGDFTLNVIESVPDFGVVSYLADAEGNINVGSTMTPVQRKPSSRSFPTTPSTVTSTLTSTPTNANPQNKTTANENQSSSTDPPSPISDNQTTSTPLNPPDQSSGTPVPQNQTSDPPIHSNPQCSSPTEEEEESVDDGKMTAVVEVTVNLGLSPLKADAAEDLTEAVSTPEPETACPTEPENDSEEPTPDPDTAN", "length": 1640, "header": "tr|A0A8M3AUS9-1|A0A8M6Z7G3_DANRE Computationally mapped isoform of Myomesin-1 OS=Danio rerio OX=7955 GN=myom1b PE=1 SV=1 CANONICAL=A0A8M6Z7G3-1" }, "locus": {} }, { "isoform_ac": "A0A8M3B4K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3/entry#A0A8M3B4K5-1", "sequence": { "sequence": "MSGSIPFYQKHHRHYDRSYRSRETESAISQYQQSSSSYSAHSSKSSKGIRAATYTALDEGLSPLPKRAKPTYLAMDKENQIIGYVVPIFRGSHDFASGLSDSEEARAKVSAGYVSGRELFSSGVESERSRRTVMRESAERIQLSKRIHENEEYHKRQNEDSLMHTPEFVIKPRSHTVWEKQCVRLHCTISGWPDPRVVWYKNNVSIDPMSNPGKYKVESSYNVHSLEINRCDFDDTAQYRVSAMNSKGENSAYASVVVKRFKGEFDESLPSPRLQSRKFGFQAPCLEYGVTFETHIVEKFGVAFGREGETLSFGCSVIIYPSLQRFQPEIEWYRDDKLLVPSKWVQMHWSGDRATLTLTHLNKEDEGLYTLRVITKSGFQSHSAYVFVRDADADVAGAPGAPLDVHCLDANKDYVIVAWKQPAVDGGSAILGYFVDRCEVGTTHWAQCNDTPVKFARFPVTGLIEGRSYTFRVRAVNKAGMSHPSRVSEPVAAMDPADRSRKGASAPWTGQIIVTEEEPVEGVVPGRPQELSVIEATKNYVVLSWKPPGEKGHEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYRFRVRCCNSAGVGEPSEPTDATTVGDKLDIPSAPGRVVPTRNTDTSVVISWEASRDAKELVGYYIESSIAGSNTWEPCNNKPVKATRFICHGLTTGESYVFRVRAVNAAGISEFSQESEAIVVKAAIASPAPPYGISVLECVRDSMVLAWKQPTFIGGADITGYFVDYREVTGGVPGKWHEANIKAISERAYRVSELKENMLYQFQVRAANMAGVGIPSLPSETFKCEEWTIAVPGPPHDLQVQEVRKNSLVLLWKPPVYQGRDAVNGYYIDIKEAEADFEMWRGVNEKATDKAFFKVNDLKGGESYVFRVRAQNKAGVGKASDPTEPVEAVTKPGTAEIVVNVDDEGVISLNFECSNLTGDSKFVWSKNYEEMTEPERMTLETKGSKSKAIFNSPSEEDLGIYSCFVTHTDGASASYTFSEEALKELLKVSHDHKFPIIPLKTELAVELLEKGRVRFWLQAAKISANAKVEYVFNDNMISQGEKYKMNFDKNTGIIEMFMESLGKEDEGTFTFQLQDGKATNQSSLVLIGDVFKQLQKESEFQRKEWHRKQGPHFVEYLGYEVTPECCVRLKCKVGNMKKDSTALWYKDGREVKVDEKLDFSEGVLTLEIAQISKKDAGIYEVVLKDERGKDTSTLNLTDQGFKDLMNQVFSVIANSSTPLKIQSTEEGIRLYTFVSYYNDELHVTWHHKDAAIAFTERIKSGVVGEQLWLQISEPTEKDKGKYAIEFFDGKGGLRRTVELAGQAFDDAFAEFQRLKAAAIAERNRARVAGGLPDVVTIQEGKSLNLTCNIWGDPVPEVTWLKNEREMVSDDHYILKFESGKFASFTITSVNTADSGKYSILVKNKYGTESGDFTVSVFLPDEEHGKKK", "length": 1465, "header": "tr|A0A8M3B4K5-1|A0A8M6Z7G3_DANRE Computationally mapped isoform of Myomesin-1 OS=Danio rerio OX=7955 GN=myom1b PE=1 SV=1 CANONICAL=A0A8M6Z7G3-1" }, "locus": {} }, { "isoform_ac": "A0A8M3BBG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3/entry#A0A8M3BBG1-1", "sequence": { "sequence": "MSGSIPFYQKHHRHYDRSYRSRETESAISQYQQSSSSYSAHSSKSSKGIRAATYTALDEGLSPLPKRAKPTYLAMDKENQIIGYVVPIFRGSHDFASGLSDSEEARAKVSAGYVSGRELFSSGVESERSRRTVMRESAERIQLSKRIHENEEYHKRQNEDSLMHTPEFVIKPRSHTVWEKQCVRLHCTISGWPDPRVVWYKNNVSIDPMSNPGKYKVESSYNVHSLEINRCDFDDTAQYRVSAMNSKGENSAYASVVVKRFKGEFDESLPSPRLPPCLEYGVTFETHIVEKFGVAFGREGETLSFGCSVIIYPSLQRFQPEIEWYRDDKLLVPSKWVQMHWSGDRATLTLTHLNKEDEGLYTLRVITKSGFQSHSAYVFVRDADADVAGAPGAPLDVHCLDANKDYVIVAWKQPAVDGGSAILGYFVDRCEVGTTHWAQCNDTPVKFARFPVTGLIEGRSYTFRVRAVNKAGMSHPSRVSEPVAAMDPADRSRKGASAPWTGQIIVTEEEPVEGVVPGRPQELSVIEATKNYVVLSWKPPGEKGHEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYRFRVRCCNSAGVGEPSEPTDATTVGDKLDIPSAPGRVVPTRNTDTSVVISWEASRDAKELVGYYIESSIAGSNTWEPCNNKPVKATRFICHGLTTGESYVFRVRAVNAAGISEFSQESEAIVVKAAIGGGVLHASPAPPYGISVLECVRDSMVLAWKQPTFIGGADITGYFVDYREVTGGVPGKWHEANIKAISERAYRVSELKENMLYQFQVRAANMAGVGIPSLPSETFKCEEWTIAVPGPPHDLQVQEVRKNSLVLLWKPPVYQGRDAVNGYYIDIKEAEADFEMWRGVNEKATDKAFFKVNDLKGGESYVFRVRAQNKAGVGKASDPTEPVEAVTKPGTAEIVVNVDDEGVISLNFECSNLTGDSKFVWSKNYEEMTEPERMTLETKGSKSKAIFNSPSEEDLGIYSCFVTHTDGASASYTFSEEALKELLKVSHDHKFPIIPLKTELAVELLEKGRVRFWLQAAKISANAKVEYVFNDNMISQGEKYKMNFDKNTGIIEMFMESLGKEDEGTFTFQLQDGKATNQSSLVLIGDVFKQLQKESEFQRKEWHRKQGPHFVEYLGYEVTPECCVRLKCKVGNMKKDSTALWYKDGREVKVDEKLDFSEGVLTLEIAQISKKDAGIYEVVLKDERGKDTSTLNLTDQGFKDLMNQVFSVIANSSTPLKIQSTEEGIRLYTFVSYYNDELHVTWHHKDAAIAFTERIKSGVVGEQLWLQISEPTEKDKGKYAIEFFDGKGGLRRTVELAGQAFDDAFAEFQRLKAAAIAERNRARVAGGLPDVVTIQEGKSLNLTCNIWGDPVPEVTWLKNEREMVSDDHYILKFESGKFASFTITSVNTADSGKYSILVKNKYGTESGDFTLNVIESVPDFGVVSYLADAEGNINVGSTMTPVQRKPSSRSFPTTPSTVTSTLTSTPTNANPQNKTTANENQSSSTDPPSPISDNQTTSTPLNPPDQSSGTPVPQNQTSDPPIHSNPQCSSPTEEEEESVDDGKMTAVVEVTVNLGLSPLKADAAEDLTEAVSTPEPETACPTEPENDSEEPTPDPDTAN", "length": 1638, "header": "tr|A0A8M3BBG1-1|A0A8M6Z7G3_DANRE Computationally mapped isoform of Myomesin-1 OS=Danio rerio OX=7955 GN=myom1b PE=1 SV=1 CANONICAL=A0A8M6Z7G3-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z0A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3/entry#A0A8M6Z0A9-1", "sequence": { "sequence": "MSGSIPFYQKHHRHYDRSYRSRETESAISQYQQSSSSYSAHSSKSSKGIRAATYTALDEGLSPLPKRAKPTYLAMDKENQIIGYVVPIFRGSHDFASGLSDSEEARAKVSAGYVSGRELFSSGVESERSRRTVMRESAERIQLSKRIHENEEYHKRQNEDSLMHTPEFVIKPRSHTVWEKQCVRLHCTISGWPDPRVVWYKNNVSIDPMSNPGKYKVESSYNVHSLEINRCDFDDTAQYRVSAMNSKGENSAYASVVVKRFKGEFDESLPSPRLQSRKFGFQAPCLEYGVTFETHIVEKFGVAFGREGETLSFGCSVIIYPSLQRFQPEIEWYRDDKLLVPSKWVQMHWSGDRATLTLTHLNKEDEGLYTLRVITKSGFQSHSAYVFVRDADADVAGAPGAPLDVHCLDANKDYVIVAWKQPAVDGGSAILGYFVDRCEVGTTHWAQCNDTPVKFARFPVTGLIEGRSYTFRVRAVNKAGMSHPSRVSEPVAAMDPADRSRKGASAPWTGQIIVTEEEPVEGVVPGRPQELSVIEATKNYVVLSWKPPGEKGHEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYRFRVRCCNSAGVGEPSEPTDATTVGDKLDIPSAPGRVVPTRNTDTSVVISWEASRDAKELVGYYIESSIAGSNTWEPCNNKPVKATRFICHGLTTGESYVFRVRAVNAAGISEFSQESEAIVVKAAIGGGVLHASPAPPYGISVLECVRDSMVLAWKQPTFIGGADITGYFVDYREVTGGVPGKWHEANIKAISERAYRVSELKENMLYQFQVRAANMAGVGIPSLPSETFKCEEWTIAVPGPPHDLQVQEVRKNSLVLLWKPPVYQGRDAVNGYYIDIKEAEADFEMWRGVNEKATDKAFFKVNDLKGGESYVFRVRAQNKAGVGKASDPTEPVEAVTKPGTAEIVVNVDDEGVISLNFECSNLTGDSKFVWSKNYEEMTEPERMTLETKGSKSKAIFNSPSEEDLGIYSCFVTHTDGASASYTFSEEALKELLKVSHDHKFPIIPLKTELAVELLEKGRVRFWLQAAKISANAKVEYVFNDNMISQGEKYKMNFDKNTGIIEMFMESLGKEDEGTFTFQLQDGKATNQSSLVLIGDVFKQLQKESEFQRKEWHRKQGPHFVEYLGYEVTPECCVRLKCKVGNMKKDSTALWYKDGREVKVDEKLDFSEGVLTLEIAQISKKDAGIYEVVLKDERGKDTSTLNLTDQGFKDLMNQVFSVIANSSTPLKIQSTEEGIRLYTFVSYYNDELHVTWHHKDAAIAFTERIKSGVVGEQLWLQISEPTEKDKGKYAIEFFDGKGGLRRTVELAGQAFDDAFAEFQRLKAAAIAERNRARVAGGLPDVVTIQEGKSLNLTCNIWGDPVPEVTWLKNEREMVSDDHYILKFESGKFASFTITSVNTADSGKYSILVKNKYGTESGDFTLNVIESVPDFGVVSYLADAEGNINVGSTMTPVQRKPSSRSFPTTPSTVTSTLTSTPTNANPQNKTTANENQSSSTDPPSPISDNQTTSTPLNPPDQSSGTPVPQNQTSDPPIHSNPQCSSPTEEEEESVDDGKMTAVVEADAAEDLTEAVSTPEPETACPTEPENDSEEPTPDPDTAN", "length": 1635, "header": "tr|A0A8M6Z0A9-1|A0A8M6Z7G3_DANRE Computationally mapped isoform of Myomesin-1 OS=Danio rerio OX=7955 GN=myom1b PE=1 SV=1 CANONICAL=A0A8M6Z7G3-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z7G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3/entry#A0A8M6Z7G3-1", "sequence": { "sequence": "MSGSIPFYQKHHRHYDRSYRSRETESAISQYQQSSSSYSAHSSKSSKGIRAATYTALDEGLSPLPKRAKPTYLAMDKENQIIGYVVPIFRGSHDFASGLSDSEEARAKVSAGYVSGRELFSSGVESERSRRTVMRESAERIQLSKRIHENEEYHKRQNEDSLMHTPEFVIKPRSHTVWEKQCVRLHCTISGWPDPRVVWYKNNVSIDPMSNPGKYKVESSYNVHSLEINRCDFDDTAQYRVSAMNSKGENSAYASVVVKRFKGEFDESLPSPRLQSRKFGFQAPCLEYGVTFETHIVEKFGVAFGREGETLSFGCSVIIYPSLQRFQPEIEWYRDDKLLVPSKWVQMHWSGDRATLTLTHLNKEDEGLYTLRVITKSGFQSHSAYVFVRDADADVAGAPGAPLDVHCLDANKDYVIVAWKQPAVDGGSAILGYFVDRCEVGTTHWAQCNDTPVKFARFPVTGLIEGRSYTFRVRAVNKAGMSHPSRVSEPVAAMDPADRSRKGASAPWTGQIIVTEEEPVEGVVPGRPQELSVIEATKNYVVLSWKPPGEKGHEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYRFRVRCCNSAGVGEPSEPTDATTVGDKLDIPSAPGRVVPTRNTDTSVVISWEASRDAKELVGYYIESSIAGSNTWEPCNNKPVKATRFICHGLTTGESYVFRVRAVNAAGISEFSQESEAIVVKAAIGGGVLHASPAPPYGISVLECVRDSMVLAWKQPTFIGGADITGYFVDYREVTGGVPGKWHEANIKAISERAYRVSELKENMLYQFQVRAANMAGVGIPSLPSETFKCEEWTIAVPGPPHDLQVQEVRKNSLVLLWKPPVYQGRDAVNGYYIDIKEAEADFEMWRGVNEKATDKAFFKVNDLKGGESYVFRVRAQNKAGVGKASDPTEPVEAVTKPGTAEIVVNVDDEGVISLNFECSNLTGDSKFVWSKNYEEMTEPERMTLETKGSKSKAIFNSPSEEDLGIYSCFVTHTDGASASYTFSEEALKELLKVSHDHKFPIIPLKTELAVELLEKGRVRFWLQAAKISANAKVEYVFNDNMISQGEKYKMNFDKNTGIIEMFMESLGKEDEGTFTFQLQDGKATNQSSLVLIGDVFKQLQKESEFQRKEWHRKQGPHFVEYLGYEVTPECCVRLKCKVGNMKKDSTALWYKDGREVKVDEKLDFSEGVLTLEIAQISKKDAGIYEVVLKDERGKDTSTLNLTDQGFKDLMNQVFSVIANSSTPLKIQSTEEGIRLYTFVSYYNDELHVTWHHKDAAIAFTERIKSGVVGEQLWLQISEPTEKDKGKYAIEFFDGKGGLRRTVELAGQAFDDAFAEFQRLKAAAIAERNRARVAGGLPDVVTIQEGKSLNLTCNIWGDPVPEVTWLKNEREMVSDDHYILKFESGKFASFTITSVNTADSGKYSILVKNKYGTESGDFTLNVIESVPDFGVVSYLADAEGNINVGSTMTPVQRKPSSRSFPTTPSTVTSTLTSTPTNANPQNKTTANENQSSSTDPPSPISDNQTTSTPLNPPDQSSGTPVPQNQTSDPPIHSNPQCSSPTEEEEESVDDGKMTAVVEVTVNLGLSPLKADAAEDLTEAVSTPEPETACPTEPENDSEEPTPDPDTAN", "length": 1646, "header": "tr|A0A8M6Z7G3-1|A0A8M6Z7G3_DANRE Isoform 1 of Myomesin-1 OS=Danio rerio OX=7955 GN=myom1b PE=1 SV=1 CANONICAL=A0A8M6Z7G3-1" }, "locus": {} }, { "isoform_ac": "A0AC58G1Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3/entry#A0AC58G1Q2-1", "sequence": { "sequence": "MSGSIPFYQKHHRHYDRSYRSRETESAISQYQQSSSSYSAHSSKSSKGIRAATYTALDEGLSPLPKRAKPTYLAMDKENQIIGYVVPIFRGSHDFASGLSDSEEARAKVSAGYVSGRELFSSGVESERSRRTVMRESAERIQLSKRIHENEEYHKRQNEDSLMHTPEFVIKPRSHTVWEKQCVRLHCTISGWPDPRVVWYKNNVSIDPMSNPGKYKVESSYNVHSLEINRCDFDDTAQYRVSAMNSKGENSAYASVVVKRFKGEFDESLPSPRLPPCLEYGVTFETHIVEKFGVAFGREGETLSFGCSVIIYPSLQRFQPEIEWYRDDKLLVPSKWVQMHWSGDRATLTLTHLNKEDEGLYTLRVITKSGFQSHSAYVFVRDADADVAGAPGAPLDVHCLDANKDYVIVAWKQPAVDGGSAILGYFVDRCEVGTTHWAQCNDTPVKFARFPVTGLIEGRSYTFRVRAVNKAGMSHPSRVSEPVAAMDPADRSRKGASAPWTGQIIVTEEEPVEGVVPGRPQELSVIEATKNYVVLSWKPPGEKGHEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYRFRVRCCNSAGVGEPSEPTDATTVGDKLDIPSAPGRVVPTRNTDTSVVISWEASRDAKELVGYYIESSIAGSNTWEPCNNKPVKATRFICHGLTTGESYVFRVRAVNAAGISEFSQESEAIVVKAAIASPAPPYGISVLECVRDSMVLAWKQPTFIGGADITGYFVDYREVTGGVPGKWHEANIKAISERAYRVSELKENMLYQFQVRAANMAGVGIPSLPSETFKCEEWTIAVPGPPHDLQVQEVRKNSLVLLWKPPVYQGRDAVNGYYIDIKEAEADFEMWRGVNEKATDKAFFKVNDLKGGESYVFRVRAQNKAGVGKASDPTEPVEAVTKPGTAEIVVNVDDEGVISLNFECSNLTGDSKFVWSKNYEEMTEPERMTLETKGSKSKAIFNSPSEEDLGIYSCFVTHTDGASASYTFSEEALKELLKVSHDHKFPIIPLKTELAVELLEKGRVRFWLQAAKISANAKVEYVFNDNMISQGEKYKMNFDKNTGIIEMFMESLGKEDEGTFTFQLQDGKATNQSSLVLIGDVFKQLQKESEFQRKEWHRKQGPHFVEYLGYEVTPECCVRLKCKVGNMKKDSTALWYKDGREVKVDEKLDFSEGVLTLEIAQISKKDAGIYEVVLKDERGKDTSTLNLTDQGFKDLMNQVFSVIANSSTPLKIQSTEEGIRLYTFVSYYNDELHVTWHHKDAAIAFTERIKSGVVGEQLWLQISEPTEKDKGKYAIEFFDGKGGLRRTVELAGQAFDDAFAEFQRLKAAAIAERNRARVAGGLPDVVTIQEGKSLNLTCNIWGDPVPEVTWLKNEREMVSDDHYILKFESGKFASFTITSVNTADSGKYSILVKNKYGTESGDFTLNVIESVPDFGVVSYLADAEGNINVGSTMTPVQRKPSSRSFPTTPSTVTSTLTSTPTNANPQNKTTANENQSSSTDPPSPISDNQTTSTPLNPPDQSSGTPVPQNQTSDPPIHSNPQCSSPTEEEEESVDDGKMTAVVEVTVNLGLSPLKADAAEDLTEAVSTPEPETACPTEPENDSEEPTPDPDTAN", "length": 1632, "header": "tr|A0AC58G1Q2-1|A0AC58G1Q2_DANRE Computationally mapped isoform of Myomesin-1 OS=Danio rerio OX=7955 GN=myom1b PE=1 SV=1 CANONICAL=A0A8M6Z7G3-1" }, "locus": {} }, { "isoform_ac": "A0AC58G1R3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3/entry#A0AC58G1R3-1", "sequence": { "sequence": "MSGSIPFYQKHHRHYDRSYRSRETESAISQYQQSSSSYSAHSSKSSKGIRAATYTALDEGLSPLPKRAKPTYLAMDKENQIIGYVVPIFRGSHDFASGLSDSEEARAKVSAGYVSGRELFSSGVESERSRRTVMRESAERIQLSKRIHENEEYHKRQNEDSLMHTPEFVIKPRSHTVWEKQCVRLHCTISGWPDPRVVWYKNNVSIDPMSNPGKYKVESSYNVHSLEINRCDFDDTAQYRVSAMNSKGENSAYASVVVKRFKGEFDESLPSPRLQSRKFGFQAPCLEYGVTFETHIVEKFGVAFGREGETLSFGCSVIIYPSLQRFQPEIEWYRDDKLLVPSKWVQMHWSGDRATLTLTHLNKEDEGLYTLRVITKSGFQSHSAYVFVRDADADVAGAPGAPLDVHCLDANKDYVIVAWKQPAVDGGSAILGYFVDRCEVGTTHWAQCNDTPVKFARFPVTGLIEGRSYTFRVRAVNKAGMSHPSRVSEPVAAMDPADRSRKGASAPWTGQIIVTEEEPVEGVVPGRPQELSVIEATKNYVVLSWKPPGEKGHEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYRFRVRCCNSAGVGEPSEPTDATTVGDKLDIPSAPGRVVPTRNTDTSVVISWEASRDAKELVGYYIESSIAGSNTWEPCNNKPVKATRFICHGLTTGESYVFRVRAVNAAGISEFSQESEAIVVKAAIASPAPPYGISVLECVRDSMVLAWKQPTFIGGADITGYFVDYREVTGGVPGKWHEANIKAISERAYRVSELKENMLYQFQVRAANMAGVGIPSLPSETFKCEEWTIAVPGPPHDLQVQEVRKNSLVLLWKPPVYQGRDAVNGYYIDIKEAEADFEMWRGVNEKATDKAFFKVNDLKGGESYVFRVRAQNKAGVGKASDPTEPVEAVTKPGTAEIVVNVDDEGVISLNFECSNLTGDSKFVWSKNYEEMTEPERMTLETKGSKSKAIFNSPSEEDLGIYSCFVTHTDGASASYTFSEEALKELLKVSHDHKFPIIPLKTELAVELLEKGRVRFWLQAAKISANAKVEYVFNDNMISQGEKYKMNFDKNTGIIEMFMESLGKEDEGTFTFQLQDGKATNQSSLVLIGDVFKQLQKESEFQRKEWHRKQGPHFVEYLGYEVTPECCVRLKCKVGNMKKDSTALWYKDGREVKVDEKLDFSEGVLTLEIAQISKKDAGIYEVVLKDERGKDTSTLNLTDQGFKDLMNQVFSVIANSSTPLKIQSTEEGIRLYTFVSYYNDELHVTWHHKDAAIAFTERIKSGVVGEQLWLQISEPTEKDKGKYAIEFFDGKGGLRRTVELAGQAFDDAFAEFQRLKAAAIAERNRARVAGGLPDVVTIQEGKSLNLTCNIWGDPVPEVTWLKNEREMVSDDHYILKFESGKFASFTITSVNTADSGKYSILVKNKYGTESGDFTLNVIESVPDFGVVSYLADAEGNINVGSTMTPVQRKPSSRSFPTTPSTVTSTLTSTPTNANPQNKTTANENQSSSTDPPSPISDNQTTSTPLNPPDQSSGTPVPQNQTSDPPIHSNPQCSSPTEEEEESVDDGKMTAVVEDAAEDLTEAVSTPEPETACPTEPENDSEEPTPDPDTAN", "length": 1628, "header": "tr|A0AC58G1R3-1|A0AC58G1R3_DANRE Computationally mapped isoform of Myomesin-1 OS=Danio rerio OX=7955 GN=myom1b PE=1 SV=1 CANONICAL=A0A8M6Z7G3-1" }, "locus": {} }, { "isoform_ac": "A0AC58G1R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3/entry#A0AC58G1R4-1", "sequence": { "sequence": "MSGSIPFYQKHHRHYDRSYRSRETESAISQYQQSSSSYSAHSSKSSKGIRAATYTALDEGLSPLPKRAKPTYLAMDKENQIIGYVVPIFRGSHDFASGLSDSEEARAKVSAGYVSGRELFSSGVESERSRRTVMRESAERIQLSKRIHENEEYHKRQNEDSLMHTPEFVIKPRSHTVWEKQCVRLHCTISGWPDPRVVWYKNNVSIDPMSNPGKYKVESSYNVHSLEINRCDFDDTAQYRVSAMNSKGENSAYASVVVKRFKGEFDESLPSPRLQSRKFGFQAPCLEYGVTFETHIVEKFGVAFGREGETLSFGCSVIIYPSLQRFQPEIEWYRDDKLLVPSKWVQMHWSGDRATLTLTHLNKEDEGLYTLRVITKSGFQSHSAYVFVRDADADVAGAPGAPLDVHCLDANKDYVIVAWKQPAVDGGSAILGYFVDRCEVGTTHWAQCNDTPVKFARFPVTGLIEGRSYTFRVRAVNKAGMSHPSRVSEPVAAMDPADRSRKGASAPWTGQIIVTEEEPVEGVVPGRPQELSVIEATKNYVVLSWKPPGEKGHEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYRFRVRCCNSAGVGEPSEPTDATTVGDKLDIPSAPGRVVPTRNTDTSVVISWEASRDAKELVGYYIESSIAGSNTWEPCNNKPVKATRFICHGLTTGESYVFRVRAVNAAGISEFSQESEAIVVKAAIASPAPPYGISVLECVRDSMVLAWKQPTFIGGADITGYFVDYREVTGGVPGKWHEANIKAISERAYRVSELKENMLYQFQVRAANMAGVGIPSLPSETFKCEEWTIAVPGPPHDLQVQEVRKNSLVLLWKPPVYQGRDAVNGYYIDIKEAEADFEMWRGVNEKATDKAFFKVNDLKGGESYVFRVRAQNKAGVGKASDPTEPVEAVTKPGTAEIVVNVDDEGVISLNFECSNLTGDSKFVWSKNYEEMTEPERMTLETKGSKSKAIFNSPSEEDLGIYSCFVTHTDGASASYTFSEEALKELLKVSHDHKFPIIPLKTELAVELLEKGRVRFWLQAAKISANAKVEYVFNDNMISQGEKYKMNFDKNTGIIEMFMESLGKEDEGTFTFQLQDGKATNQSSLVLIGDVFKQLQKESEFQRKEWHRKQGPHFVEYLGYEVTPECCVRLKCKVGNMKKDSTALWYKDGREVKVDEKLDFSEGVLTLEIAQISKKDAGIYEVVLKDERGKDTSTLNLTDQGFKDLMNQVFSVIANSSTPLKIQSTEEGIRLYTFVSYYNDELHVTWHHKDAAIAFTERIKSGVVGEQLWLQISEPTEKDKGKYAIEFFDGKGGLRRTVELAGQAFDDAFAEFQRLKAAAIAERNRARVAGGLPDVVTIQEGKSLNLTCNIWGDPVPEVTWLKNEREMVSDDHYILKFESGKFASFTITSVNTADSGKYSILVKNKYGTESGDFTLNVIESVPDFGVVSYLADAEGNINVGSTMTPVQRKPSSRSFPTTPSTVTSTLTSTPTNANPQNKTTANENQSSSTDPPSPISDNQTTSTPLNPPDQSSGTPVPQNQTSDPPIHSNPQCSSPTEEEEESVDDGKMTAVVEADAAEDLTEAVSTPEPETACPTEPENDSEEPTPDPDTAN", "length": 1629, "header": "tr|A0AC58G1R4-1|A0AC58G1R4_DANRE Computationally mapped isoform of Myomesin-1 OS=Danio rerio OX=7955 GN=myom1b PE=1 SV=1 CANONICAL=A0A8M6Z7G3-1" }, "locus": {} }, { "isoform_ac": "A0AC58G1Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3/entry#A0AC58G1Y8-1", "sequence": { "sequence": "MSGSIPFYQKHHRHYDRSYRSRETESAISQYQQSSSSYSAHSSKSSKGIRAATYTALDEGLSPLPKRAKPTYLAMDKENQIIGYVVPIFRGSHDFASGLSDSEEARAKVSAGYVSGRELFSSGVESERSRRTVMRESAERIQLSKRIHENEEYHKRQNEDSLMHTPEFVIKPRSHTVWEKQCVRLHCTISGWPDPRVVWYKNNVSIDPMSNPGKYKVESSYNVHSLEINRCDFDDTAQYRVSAMNSKGENSAYASVVVKRFKGEFDESLPSPRLPPCLEYGVTFETHIVEKFGVAFGREGETLSFGCSVIIYPSLQRFQPEIEWYRDDKLLVPSKWVQMHWSGDRATLTLTHLNKEDEGLYTLRVITKSGFQSHSAYVFVRDADADVAGAPGAPLDVHCLDANKDYVIVAWKQPAVDGGSAILGYFVDRCEVGTTHWAQCNDTPVKFARFPVTGLIEGRSYTFRVRAVNKAGMSHPSRVSEPVAAMDPADRSRKGASAPWTGQIIVTEEEPVEGVVPGRPQELSVIEATKNYVVLSWKPPGEKGHEGVMYYVEKCVSGTDSWQRVNTEIPVKSPRFALFDLAEGKSYRFRVRCCNSAGVGEPSEPTDATTVGDKLDIPSAPGRVVPTRNTDTSVVISWEASRDAKELVGYYIESSIAGSNTWEPCNNKPVKATRFICHGLTTGESYVFRVRAVNAAGISEFSQESEAIVVKAAIASPAPPYGISVLECVRDSMVLAWKQPTFIGGADITGYFVDYREVTGGVPGKWHEANIKAISERAYRVSELKENMLYQFQVRAANMAGVGIPSLPSETFKCEEWTIAVPGPPHDLQVQEVRKNSLVLLWKPPVYQGRDAVNGYYIDIKEAEADFEMWRGVNEKATDKAFFKVNDLKGGESYVFRVRAQNKAGVGKASDPTEPVEAVTKPGTAEIVVNVDDEGVISLNFECSNLTGDSKFVWSKNYEEMTEPERMTLETKGSKSKAIFNSPSEEDLGIYSCFVTHTDGASASYTFSEEALKELLKVSHDHKFPIIPLKTELAVELLEKGRVRFWLQAAKISANAKVEYVFNDNMISQGEKYKMNFDKNTGIIEMFMESLGKEDEGTFTFQLQDGKATNQSSLVLIGDVFKQLQKESEFQRKEWHRKQGPHFVEYLGYEVTPECCVRLKCKVGNMKKDSTALWYKDGREVKVDEKLDFSEGVLTLEIAQISKKDAGIYEVVLKDERGKDTSTLNLTDQGFKDLMNQVFSVIANSSTPLKIQSTEEGIRLYTFVSYYNDELHVTWHHKDAAIAFTERIKSGVVGEQLWLQISEPTEKDKGKYAIEFFDGKGGLRRTVELAGQAFDDAFAEFQRLKAAAIAERNRARVAGGLPDVVTIQEGKSLNLTCNIWGDPVPEVTWLKNEREMVSDDHYILKFESGKFASFTITSVNTADSGKYSILVKNKYGTESGDFTVSVFLPDEEHGKKK", "length": 1457, "header": "tr|A0AC58G1Y8-1|A0AC58G1Y8_DANRE Computationally mapped isoform of Myomesin-1 OS=Danio rerio OX=7955 GN=myom1b PE=1 SV=1 CANONICAL=A0A8M6Z7G3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1639, "start_aa": "Thr", "end_pos": 1639, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1639", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100144770", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100144770", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GBP8-1", "protein_name": "Myomesin-1", "gene_name": "Myom1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLPFYQRSHQHYDLSYRNKDLHTTMSHYQQEKKRSAVYTHGSTAYSSRSSAAHRQESEALRQASAASYQQQASKAYSLGTSSSQHYQGSEVSRKTASSYDYGYSHGLTDSSLLLEDYSSRLSPQTKRAKRSLLSGEETGNLSGNYMVPIYSGRQVHISGIRDSEEERIKEAAAYIAQRTLLESEEAIMASKQSTASKQSTASKQSIASKQSTASKQSTASKQSTASKQATSTFQQEETFERKSRNISIREKAEELSLRKTLEETQAYHGKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSVAGWPEPRLTWYKNQVPINVHANPEKYIIESRYGMHTLEISKCDFEDTAQYRASAMNVQGEVSAYASVVVKRYKGELDDSLLRGGVSMPLSFAVTPYGYASKFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHVQPEVQWYRNGAPVSPSKWVQPHWSGDRATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVVSLDANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKTGIGLPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPTEGVIPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCDVGTENWQRVNTELPVKSPRFALFDLVEGKSYRFRVRCSNSAGVGEPSESTEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIESSVVGSGQWEPCNNNPVKGSRFTCHGLTTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVWPQLSDTPGGLTDSGGAMSGASPPTSQKDALPSSKPNKPSPPSSPSNRGQKEVSKVNGSVQEELSPPSMEVASKEQSKSGPPEKKKDPVAVPSPPYDITCLESFRDSMVLGWKQPDKTGGAEITGYYVNYREVVGGVPGKWREANIKAVSDAAYKISELKENTVYQFQVSAMNIAGLGAPSAVSECFKCEEWTIAVPGPPHSLKLSEVRKNSLVLQWKPPVYSGRTPVTGYFVDLKEASAKDDQWRGLNEAAIPNKYLRVQGLKEGISYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDQMTPKSEFVWSKDYVPSEDSPRLEVESKGNKTKMVFKDLGPDDLGTYSCDVTDTDGIASSYLIDEEEMKRLLALSQEHKFPTVPTKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQIQDGKATGHSTLVLIGDVYKKLQKEAEFQRQEWIRKQGPHFAEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGFYEVILKDDRGKDKSRLKLVDEAFQDLMTEVCRKIALSATDLKIQSTAEGIRLYSFVCYYLDDLKVNWSHNGTGIKYTDRVKSGVTGEQIWLQINEPTQNDKGKYVMELFDGKTGHQKSVDLSGQAFDEAFAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPTPEVSWLKNEKPLTSDDHCSLKFEAGKTAFFTISGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARKGASEPPKGNQKSK", "length": 1689 }, "evidence": [ { "id": "RGD:631436", "url": "https://alliancegenome.org/gene/RGD:631436#orthology", "database": "AGR" }, { "id": "HGNC:7613", "url": "https://alliancegenome.org/gene/HGNC:7613#orthology", "database": "AGR" }, { "id": "MGI:1341430", "url": "https://alliancegenome.org/gene/MGI:1341430#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080416-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080416-2#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1NUG4-1", "protein_name": "Myomesin 1a (Skelemin)", "gene_name": "myom1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSESLKLQKEQEERDLETRYESSYHQSSLSSVSRQSYTAYVSSHGHKISGKKKEKKLTPLSKKEKRSYLAVDKEDEVIGYVVPVFRSSHLATQDLMETQEEVKEEGVGYVVMRNLFARESGFKMRTVKKTRETSMRESAERMALSQKLHEKEQFQKKMNPDSLTHPPEFIVKPRGQTVWEGKSVTLHCTVAGWPKPRVAWYKNNVLIDAKARPEKYFTESQYNMHSLEIKNCTFSDTAEYRISALNVKGESSAFAPVIIKRFKEEEELVERPHGYSPEYGVTFNTTIIDKFDVSFGREGETMSLGCTVIVYPTVKRYQPEIVWYRNGVALSSSKWVHMHWSGEKATLTLVHLNKEDEGLYTLRVNTKSGFDTHSAYVFVRDADVEEEGVPVAPLDVRCHDANKDYVVVTWKQPAVEGSSAITGYFIDRLEVGNHHWTQCNDTPVKYARFPVTGLIEGRSYMFRVRALNNAGVSRPSRVSDPVVAMDPSDRARLRAGPSAPWTGVIKFTEEDPTVGVIPGPPTDLAVTEATKSYVVLSWKPPVQRGHEGVMYYVEKCLVGTDAWQRVNTGIPVKSPRFALFDLAEDKSYTFRVRSCNSAGVGEPSEETGATTVGDRLDLPSAPGPVIPIRNTDSSVVVCWGASKEVKDLVGYYIEVTVDGSGVWAPCNNKPVKGTRFVCHGLNATDKCTFRVKAVNAAGYSGSSAESEACLVKASIAVPSPPTGVTTLERLRDYMVIGWQAPAKTGGADIRGYYLDYRTVKDGVTSKWHELNLKAVTSSPYKVTDLKENEFYQFQVRAFNQAGISEASIPTAPLECKEWTVAVPGPPHGLRVQEVRKDSMVVLWEPPTFNGRSPVTGYYVDFKEENGRWRCVQERSTKHTYMKVSGLQEGISYRLRIHAKNLAGVGVPSKATDAILAETRPGTNEIVVDVDDNGVISLIFECSDLKEDSQFVWSKNYEAFTDSSRLTIQTTGGKSRAIFNDPSLDDLGIYSCVVTNTDGVSASYTLTEEGLKRLLDISHDHQFPIIPFKSEMAIELQEKGRVRFWAEVGKFTSNLQVEYVFNDNVIHEGKKYTMNFNKSTGIIEMFMDLLEVTDEGTFTFNLVDGKATGRTSLVLIGEEFAELQKKSEFERAEWVRRQGPHFVEYLSFEVTPECDVHLKCKVGNIKPATEIAWFKDGIEIEEDDEDAKKIGKSDEVLTFDIGKLVIKSEKAERKKKPATEESPSKPKISKKDAGVYEVKLKDERGKDKTLLNLTDAGYQAVLNEVFRVIANSSTELKVMSTEHGIILYSFVVHYLEDLRVGWLHKESKISHSDRVQCGVTGEQLWLKINEPTEKDKGKYAIDIFDGKGSVKRVLDLSGQVWEEAFEEFKRLKAAAIAERNRARVVGGLPDVVTIQEGKSLNLTGNVWGDPAPEVSWIKNEKPLVCDEHHTLKYEHSKFASITIAAVTTTDSGKYALLVKNKYGTEAAEFTVSVYIPEDEAEKKE", "length": 1483 }, "evidence": [ { "id": "RGD:631436", "url": "https://alliancegenome.org/gene/RGD:631436#orthology", "database": "AGR" }, { "id": "HGNC:7613", "url": "https://alliancegenome.org/gene/HGNC:7613#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P52179-1", "protein_name": "Myomesin-1", "gene_name": "MYOM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLPFYQRCHQHYDLSYRNKDVRSTVSHYQREKKRSAVYTQGSTAYSSRSSAAHRRESEAFRRASASSSQQQASQHALSSEVSRKAASAYDYGSSHGLTDSSLLLDDYSSKLSPKPKRAKHSLLSGEEKENLPSDYMVPIFSGRQKHVSGITDTEEERIKEAAAYIAQRNLLASEEGITTSKQSTASKQTTASKQSTASKQSTASKQSTASRQSTASRQSVVSKQATSALQQEETSEKKSRKVVIREKAERLSLRKTLEETETYHAKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESKDAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPSLPSSSQNLGQTEVSKVSETVQEELTPPPQKAAPQGKSKSDPLKKKTDRAPPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAEFQRQEWIRKQGPHFVEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKLVDEAFKELMMEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEEARMAALESLKGGKKAK", "length": 1685 }, "evidence": [ { "id": "RGD:631436", "url": "https://alliancegenome.org/gene/RGD:631436#orthology", "database": "AGR" }, { "id": "HGNC:7613", "url": "https://alliancegenome.org/gene/HGNC:7613#orthology", "database": "AGR" }, { "id": "MGI:1341430", "url": "https://alliancegenome.org/gene/MGI:1341430#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080416-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080416-2#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62234-1", "protein_name": "Myomesin-1", "gene_name": "Myom1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLPFYQRSHQHYDLSYRNKDLRTTMSHYQQEKKRSAVYTHGSTAYSSRSLAARRQESEAFSQASATSYQQQASQTYSLGASSSSRHSQGSEVSRKTASAYDYGYSHGLTDSSLLLEDYSSKLSPQTKRAKRSLLSGEETGSLPGNYLVPIYSGRQVHISGIRDSEEERIKEAAAYIAQKTLLASEEAIAASKQSTASKQSATSKRTTSTLQREETFEKKSRNIAIREKAEELSLKKTLEETQTYHGKLNEDHLLHAPEFIIKPRSHTVWEKENVKLHCSVAGWPEPRLTWYKNQVPINVHANPGKYIIESRYGMHTLEISKCDFEDTAQYRASAMNVQGELSAYASVVVKRYKGELDESLLRGGVSMPLSFAVTPYGYASKFEIHFDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEVQWYRNGAPVSPSKWVQPHWSGDRATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVVSLDANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDTWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKTGIGLPSRVSEPVAALDPAEKARLKSHPSAPWTGQIIVTEEEPTEGVIPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIMYFVEKCDVGAENWQRVNTELPVKSPRFALFDLVEGKSYRFRVRCSNSAGVGEPSETTEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWEESRDAKELVGYYIEASVVGSGKWEPCNNNPVKGSRFTCHGLTTAQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIGGGVSPDVWPQLSDTPGGLTDSRGGMNGASPPTSQKDALLGSNPNKPSPPSSPSSRGQKEVSTVSESVQEPLSSPPQEAAPEEEQSQSEPPKKKKDPVAVPSAPYDITCLESFRDSMVLGWKQPDTTGGAEITGYYVNYREVVGEVPGKWREANIKAVSDAAYKISNLKENTLYQFQVSAMNIAGLGAPSTVSECFKCEEWTIAVPGPPHSVKLSEVRKNSLVLQWKPPVYSGRTPVTGYFVDLKEASAKDDQWRGLNEAAIVNKYLRVQGLKEGTSYVFRVRAVNQAGVGKPSDLAGPVVAETRPGTKEVVVSVDDDGVISLNFECDQMTPKSEFVWSKDYVPTEDSPRLEVENKGDKTKMTFKDLGTDDLGTYSCDVTDTDGIASSYLIDEEEMKRLLALSQEHKFPTVPTKSELAVEILEKGQVRFWMQAEKLSSNAKVSYIFNEKEIFEGPKYKMHIDRNTGIIEMFMEKLQDEDEGTYTFQIQDGKATGHSTLVLIGDVYKKLQKEAEFQRQEWIRKQGPHFAEYLSWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDFKDGICTLLITEFSKKDAGFYEVILKDDRGKDKSRLKLVDEAFQDLMTEVCKKIALSATDLKIQSTAEGIRLYSFVCYYLDDLKVNWSHNGTGIKYTDRVKSGVTGEQIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAFDEAFAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKPLTSDDHCSLKFEAGKTAFFTISGVSTADSGKYGLVVKNKYGSETSDFTVSVFIPEEELRKGAMEPPKGNQKSK", "length": 1667 }, "evidence": [ { "id": "RGD:631436", "url": "https://alliancegenome.org/gene/RGD:631436#orthology", "database": "AGR" }, { "id": "HGNC:7613", "url": "https://alliancegenome.org/gene/HGNC:7613#orthology", "database": "AGR" }, { "id": "MGI:1341430", "url": "https://alliancegenome.org/gene/MGI:1341430#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080416-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080416-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7G3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3" } ], "pmid": "" }, { "name": "structural molecule activity", "id": "GO:0005198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005198", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7G3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3" } ], "pmid": "" }, { "name": "kinase binding", "id": "GO:0019900", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019900", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7G3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3" } ], "pmid": "" }, { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7G3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "sarcomere", "id": "GO:0030017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030017", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7G3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3" } ], "pmid": "" }, { "name": "myosin filament", "id": "GO:0032982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032982", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7G3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7G3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7G3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1124, "end_pos": 1126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1239, "end_pos": 1241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1258, "end_pos": 1260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1388, "end_pos": 1390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1520, "end_pos": 1522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1527, "end_pos": 1529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1541, "end_pos": 1543, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1562, "end_pos": 1564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1633, "end_pos": 1635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 959, "end_pos": 961, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 401, "end_pos": 496, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z7G3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7G3" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 166, "end_pos": 257, "start_aa": "Pro", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1639 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1124, "end_pos": 1126 }, { "start_pos": 1239, "end_pos": 1241 }, { "start_pos": 1258, "end_pos": 1260 }, { "start_pos": 1388, "end_pos": 1390 }, { "start_pos": 1520, "end_pos": 1522 }, { "start_pos": 1527, "end_pos": 1529 }, { "start_pos": 1541, "end_pos": 1543 }, { "start_pos": 1562, "end_pos": 1564 }, { "start_pos": 1633, "end_pos": 1635 }, { "start_pos": 203, "end_pos": 205 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 959, "end_pos": 961 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z9L3-1", "uniprot_ac": "A0A8M6Z9L3", "uniprot_id": "A0A8M6Z9L3_DANRE", "mass": { "chemical_mass": 148990.0, "monoisotopic_mass": 148990.0 }, "refseq": { "ac": "XP_017214263", "name": "protein FAM135A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214263" }, "gene_names": [ { "name": "fam135a", "type": "recommended", "evidence": [ { "id": "A0A8M6Z9L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3" } ] }, { "name": "fam135a", "type": "synonym", "evidence": [ { "id": "XP_017214263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214263" } ] }, { "name": "im:7140207", "type": "synonym", "evidence": [ { "id": "XP_017214263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214263" }, { "id": "A0A8M6Z9L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3" } ] } ], "protein_names": [ { "name": "Protein FAM135A isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z9L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#names_and_taxonomy" } ] }, { "name": "protein FAM135A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017214263", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214263" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214263" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam135a", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080130-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080130-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z9L3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z9L3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000059843", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000059843", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "566435", "url": "https://www.ncbi.nlm.nih.gov/gene/566435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566435", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566435", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TIHACLV", "url": "https://omabrowser.org/oma/group/TIHACLV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2B344", "url": "https://www.orthodb.org/?gene=A0A8M2B344", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3B870", "url": "https://www.orthodb.org/?gene=A0A8M3B870", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z1Q6", "url": "https://www.orthodb.org/?gene=A0A8M6Z1Q6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z2B8", "url": "https://www.orthodb.org/?gene=A0A8M6Z2B8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z965", "url": "https://www.orthodb.org/?gene=A0A8M6Z965", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z9L3", "url": "https://www.orthodb.org/?gene=A0A8M6Z9L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "B8A4Z2", "url": "https://www.orthodb.org/?gene=B8A4Z2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12482", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12482", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12482:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12482:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12394", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12394", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017214263", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214263", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B344", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B344", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B344-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B344-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B870", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B870", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B870-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B870-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1Q6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1Q6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2B8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z965", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z965", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z965-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z965-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z9L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1P2", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1P2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1P8", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1P8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1P8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1P9", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1P9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1P9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1Q2", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1Q3", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1R0", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1R0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A4Z2", "url": "https://www.uniprot.org/uniprotkb/B8A4Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A4Z2-1", "url": "https://www.uniprot.org/uniprotkb/B8A4Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080130-1", "url": "https://zfin.org/ZDB-GENE-080130-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTEVQATVEFSVELHKFYNVDLFQRGFYQVRASMKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKGVFLLQVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELAKPSMQVLYERVLRRPYPPGQRHVYIEELDVEVRLHELCEQVKQKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1344, "header": "tr|A0A8M6Z9L3-1|A0A8M6Z9L3_DANRE Isoform 1 of Protein FAM135A isoform X1 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B344-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#A0A8M2B344-1", "sequence": { "sequence": "MTEVQATVEFSVELHKFYNVDLFQRGFYQVRASMKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELEELDVEVRLHELCEQVKKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1311, "header": "tr|A0A8M2B344-1|A0A8M6Z9L3_DANRE Computationally mapped isoform of Protein FAM135A isoform X1 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} }, { "isoform_ac": "A0A8M3B870-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#A0A8M3B870-1", "sequence": { "sequence": "MTEVQATVEFSVELHKFYNVDLFQRGFYQVRASMKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELAKPSMQVLYERVLRRPYPPGQRHVYIEELDVEVRLHELCEQVKKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1337, "header": "tr|A0A8M3B870-1|A0A8M6Z9L3_DANRE Computationally mapped isoform of Protein FAM135A isoform X1 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z1Q6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#A0A8M6Z1Q6-1", "sequence": { "sequence": "MTEVQATVEFSVELHKFYNVDLFQRGFYQVRASMKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKGVFLLQVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELAKPSMQVLYERVLRRPYPPGQRHVYIEELDVEVRLHELCEQVKKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1343, "header": "tr|A0A8M6Z1Q6-1|A0A8M6Z9L3_DANRE Computationally mapped isoform of Protein FAM135A isoform X1 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z2B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#A0A8M6Z2B8-1", "sequence": { "sequence": "MTEVQATVEFSVELHKFYNVDLFQRGFYQVRASMKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKGVFLLQVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELEELDVEVRLHELCEQVKKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1317, "header": "tr|A0A8M6Z2B8-1|A0A8M6Z9L3_DANRE Computationally mapped isoform of Protein FAM135A isoform X1 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z965-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#A0A8M6Z965-1", "sequence": { "sequence": "MTEVQATVEFSVELHKFYNVDLFQRGFYQVRASMKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKGVFLLQVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELEELDVEVRLHELCEQVKQKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1318, "header": "tr|A0A8M6Z965-1|A0A8M6Z965_DANRE Computationally mapped isoform of Protein FAM135A isoform X5 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z9L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#A0A8M6Z9L3-1", "sequence": { "sequence": "MTEVQATVEFSVELHKFYNVDLFQRGFYQVRASMKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKGVFLLQVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELAKPSMQVLYERVLRRPYPPGQRHVYIEELDVEVRLHELCEQVKQKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1344, "header": "tr|A0A8M6Z9L3-1|A0A8M6Z9L3_DANRE Isoform 1 of Protein FAM135A isoform X1 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} }, { "isoform_ac": "A0AC58H1P2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#A0AC58H1P2-1", "sequence": { "sequence": "MKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELAKPSMQVLYERVLRRPYPPGQRHVYIEELDVEVRLHELCEQVKQKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1305, "header": "tr|A0AC58H1P2-1|A0AC58H1P2_DANRE Computationally mapped isoform of Protein FAM135A isoform X10 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} }, { "isoform_ac": "A0AC58H1P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#A0AC58H1P8-1", "sequence": { "sequence": "MTEVQATVEFSVELHKFYNVDLFQRGFYQVRASMKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELEELDVEVRLHELCEQVKQKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1312, "header": "tr|A0AC58H1P8-1|A0AC58H1P8_DANRE Computationally mapped isoform of Protein FAM135A isoform X7 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} }, { "isoform_ac": "A0AC58H1P9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#A0AC58H1P9-1", "sequence": { "sequence": "MKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELEELDVEVRLHELCEQVKQKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1279, "header": "tr|A0AC58H1P9-1|A0AC58H1P9_DANRE Computationally mapped isoform of Protein FAM135A isoform X12 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} }, { "isoform_ac": "A0AC58H1Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#A0AC58H1Q2-1", "sequence": { "sequence": "MKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELEELDVEVRLHELCEQVKKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1278, "header": "tr|A0AC58H1Q2-1|A0AC58H1Q2_DANRE Computationally mapped isoform of Protein FAM135A isoform X13 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} }, { "isoform_ac": "A0AC58H1Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#A0AC58H1Q3-1", "sequence": { "sequence": "MKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELAKPSMQVLYERVLRRPYPPGQRHVYIEELDVEVRLHELCEQVKKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1304, "header": "tr|A0AC58H1Q3-1|A0AC58H1Q3_DANRE Computationally mapped isoform of Protein FAM135A isoform X11 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} }, { "isoform_ac": "A0AC58H1R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#A0AC58H1R0-1", "sequence": { "sequence": "MKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKGVFLLQVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELAKPSMQVLYERVLRRPYPPGQRHVYIEELDVEVRLHELCEQVKQKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1311, "header": "tr|A0AC58H1R0-1|A0AC58H1R0_DANRE Computationally mapped isoform of Protein FAM135A isoform X8 OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} }, { "isoform_ac": "B8A4Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3/entry#B8A4Z2-1", "sequence": { "sequence": "MTEVQATVEFSVELHKFYNVDLFQRGFYQVRASMKVPPRIPQRVEASLLHPIGSDLAFPASVQDDVVCSKTFQILYKNEEIVVNDVFVFKVMMLLDAKKVEESLNEVDFQLCLDLFFTDGDYSPEEPSSLQSISSRTLRLHFSLHRGIHHHVNVMFDYFHLSVISATIHASLVALHQPLISFPRPVKSTWLNRNAPAQSKDSLIPPLETVVFGSTYVKQLSPDGKSFLVSDQCLQHAFSLHQNMCANLLRAYQSLFCYLTSLTKNLPASQRMELAKPSMQVLYERVLRRPYPPGQRHVYIEELDVEVRLHELCEQVKQKAESPDELAELVNMNLAQLCSLLMALWGNFLEVVSLNERVFVLLAQEHHTLRVQRFAEAFFCLEHPRQSALAYQELHAHSHQQMTTAIKSSSYFLSLPPLPVECADLDGDVNSLPIIFEDRYLESVTEDRDGPWLGLQNNRSGSVSAKADRSNSKDCIASGALGPYPDKQQASFATAWPEQNEPSLKSKAKSIKLKKNTKTENSKKLIRQSSKDSVVLTGYKNLKVPHSEKTIKSKDIDHQCNQRDELEDGGKFLLQNETTTTHCAQNAKDCTSGNLQGNATILSDGFPNLMSLQMQARPQAGTGAEAAAARVDPTHPPAGLRHIDVKPSDKDPYQGDKVTVLLPHHPERTTKRDVPEITQTDFSEFKSRVGDGATFVGPCGAALRNDNIPQASSRLSDSGIESEPSSATQLAPVSPSPFAPIGIEAPTELIPHRPPPLSPASRGATALEGLNPESTSGVSGVQSSLTSINSLPSDDEVETEATSRKSSILVQEQSLIFSGESQSLLLTNSRVLAQQKASHGDGMDSALQSRCETSASDRLVGSNETDLPGGPEACSEPQTAAQSSTSVTSSTDMVKKGFVENYFGSRSSTDISEISPLETAAITLGIQTCPNANDEEDEEEEQEHEMIENGYYEETDGVVYVNGLPEDEGRCEDGGAEGRTLFYDHLGLEQLQETYIPSAGIRTRPTGPAPTSSDLCWYKSAPTAQMTAFVQAKEELKQLKLPGFLYSEVADLASTVPYFSMDEDENCDDGIHLIVCVHGLDGNSADLRLVKTYLELGLPGARIDFLMSERNQNDTFADFESMTDRLLDEIVQYIQIYNLTVSKISFVGHSLGNLIVRSVLTRPRFKCYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLQFFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQTGPVYAEMIENLLLPVLQNKDCNLVRYDVIHALPNTANSLIGRAAHIAVLDSEIFLEKFFLVAGLKFFQ", "length": 1338, "header": "tr|B8A4Z2-1|B8A4Z2_DANRE Computationally mapped isoform of Protein FAM135A OS=Danio rerio OX=7955 GN=fam135a PE=3 SV=1 CANONICAL=A0A8M6Z9L3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1017, "start_aa": "Thr", "end_pos": 1017, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1017", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8A4Z2", "url": "https://www.uniprot.org/uniprotkb/B8A4Z2" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:566435", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566435", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZQV8-1", "protein_name": "Family with sequence similarity 135, member A", "gene_name": "Fam135a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEVQAMVEFSVELNKFYNVDLFQRGFYQIRASMKIPPRIPHRVEASLLHATGMTLAFPASVHDALVCSKTFQILYKNEEVVLNDVMIFKVKMLLDERKIEETLEEISFLLSLDLHFTDGDYSADDLNALQLISSRTLKLHYSIYRGLHHHANIMFDYFHLSVVSVTVHASLVALHQPLISFPRPVKTTWLNRSAPAQSKDSAIPTLESVVFGVNYTKQLSPDGCTFLIAEPFLQHAYHFHYTLCATLLLAFKGLHSYFITVTEEIPSCQKLDLAKASMQVLYERLLRRAQPRTQNDTCLEAMDTEARLTELCEEVKKVENPDELAELINMNLAQLCSLLMALWGQFLEAITLHEELRVLLAQEHHTLRVRRFSEAFFCFEHPREAAIAYQELHAQSHLQMCTAIKNTSFCSSLPPLPIECSELDGDLNSLPIIFEDRYLDSVIEDLDAPWMGIQSLQISEASKVDKHETEESSVAGLSSPELKVRPAVASSNCYTEGEKQLTKSLKGKNEESNKSKVKVTKLMKTMKPETTKKLIKQNSKDSVVLVSYKCLKNTASSDLTKCFEGNPSYSQKEGLDPTMCRDNFDPKTYIRQPSQKEASSLSADTDRAEHKSPDTETMHPDQSALLNSGSLNLCANLSISGKLGISQDDSDIPDTEHKLASRSPSNDCLDCQTAPSSGVRTLEVKPSSEESFSEEKVTVKIGPWTELQEDELFVNNLLPDFEALDSNDKSKSIDLPLEKDALQEAKCRCTEESLTKFRSNLPAPSTKEYHVVVSGDTIKLPDSNAAYASSRFSDSGVESEPSSFATHPNPEIAFETLQGPGPCNNERLLPQLLMKPDHNVKLSLGSHCTESTSALSEIQQSSLTSINSLPSDDELSPDDDCKRCAVADCQLSDSKTVLHPGTTSLPKWDDTKKSSVILQQQCVVFSGHLDNDTLAMHSLDLSSEDPLQLILSGEDASSGVRSHWGSKPHLDTVFTGSQSHSTSSINSVETVPTLNSKLICLGSPCVVSGSVCTDAELSEDRTVEGKSSEPLNHKQICSEGPVVESHPLSTGDDSLSSSTDVVKQGLVEDYFGSQSNTDVSDACAVTYHSLVSSQETCDKGIGDLQQEQGKEGMQDDQEMVQNGYHEETDFPATGGAVSVHCVRADELGGQRHELSENLSSDYLRAAVTVPAVCTSACLSFPSAPRESPCVKYSSRSKVDAITKQPSSISYNFTSSTSWYENSPKPQIHAFLQAKEELKQLKLPGFMYSDVPLLASSAPYFSMEEEEGSEDGVHLIVCVHGLDGNSADLRLVKTYIELGLPGGRVDFLMSERNQNDTFADFDCMTDRLLDEIIQYIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLSKLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSNKAGLHYFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQSGQIYSEMIHNLLRPVLQSKGCNLVRYNVINALPNTADSLIGRAAHIAVLDSEIFLEKFFLVAALKYFQ", "length": 1540 }, "evidence": [ { "id": "RGD:1304927", "url": "https://alliancegenome.org/gene/RGD:1304927#orthology", "database": "AGR" }, { "id": "MGI:1915437", "url": "https://alliancegenome.org/gene/MGI:1915437#orthology", "database": "AGR" }, { "id": "HGNC:21084", "url": "https://alliancegenome.org/gene/HGNC:21084#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080130-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080130-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0052333", "url": "https://alliancegenome.org/gene/FB:FBgn0052333#orthology", "database": "AGR" }, { "id": "SGD:S000005585", "url": "https://alliancegenome.org/gene/SGD:S000005585#orthology", "database": "AGR" }, { "id": "A0A8M6Z9L3", "url": "https://omabrowser.org/oma/group/A0A8M6Z9L3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1PSQ6-1", "protein_name": "Protein FAM135B", "gene_name": "fam135b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSEVQGTVEFSLELHKFHNVDLFQRGFYQVRAGLRVSPRVPHRITATTPGYTGECSFSNAGVHDGGVFSRIFQILYRNEEVTLEDHINFRLHLLLDGERVEEAVSEVDVQLKLDLHFTDNEQQLADISSVPVISSRTLGLHFHPQQGLHHHLPVMFDYFHLSVISVSIHASLVALHQPLISFARSGKGTWLGKGSPESEAPPSAMSVENLMFGAGYCKPVPTEGSFYVPSENCLQRAYTWHRRICKLLLAAHRALRSYYTTLMKEIPQLQHIQTEDLPLEETLNQLTIELQLQSGHEKVAEQISKDLTQLCAQLSALWTQFLESTVPNPYIRSYLAQEHHTLRVRRFSEAYFFTEHPKESSLTFQEELINRHAQVSTEMRNSDYLLRMPPLPVECLDIDGDWSSLPIIFEDRYVDTPCLDYNVVHEQNQAVLNSQPCFEPTRVKGQTASPAEKTQDTSLPATSPEEPPSEDCTEMPTYMTLTDHQDDDVTEHIKPRPQAETLTDHVEEADIDGCEFITTSSNSRIHSVDEVTCQYENDGNTMSVDTDDVIDNQEKTSCQKEAANESDHTSSQQTNVFNSGQPLLLVPTDLGELPDLTSLGSFEFLPTYNHDDNLETPGDTGSPDNQEPQTVFDNRHIQAPAKDYGGKDTSPGILLKATLPGTDPLVTSPSRNVIHQIRRLSETPPRGVFLGGAKLMNRSSSVISDSGIESEPSSVAWTLEGRGVVAGGRDILQSLARCRTAHQSSLEGLQTESHGSLPSATQASLTSISSLPYEEEEDRQLNTLTKSASAPQISSPDDTEEDRETPNQETRTVCEANQVTGTRCEANPMRQNKESANEVKRNLQMEETTQQDTTNVLVANHIRDEAANEVKQTLQEVTREDGNTTTNQEKRNVCVANQLRKSEVAANEVKQNLQGVFREDGNETSNQEIDIEESSNQDITDLTFVNPEMLLYQQFLMDSGKDATLEELTENSKDFQGNILLKEYLMDESTEICRCEDEYCEHKRKLESNQYHKDADDISVCHIHLNELEVASMENLPEPTTNDKRTHGIAANEKERPADPIEPPTNERDQQILEGQSRINKVPSTGLAFVNKKVVEVVNLSVSCAPTCLPFSSVLRDSPSVSGISTRQATSPITHQPLGSFGIISSNSFFGADQEINERMINFFKAKEALLRELVFRGTLYSDLPYLASEHPYFPPEEDDTEFEDGIHLVVCVHGLDGNSADLRLVKTFVELGLPGSRLDFLMSERNQTDTFADFDTMTDRLLDEIIQHIQLYNLTIHRISFIGHSLGNVIIRSVLTRPRFRCYLCKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDHTDPRQTFLYTLSKKPGLQFFKNVVLVASPQDRYVPFHSARIEMCRTALKDRTTGPVYTEMINNLLQPLLSAPNCRLIRQNVFHALPNTANTLIGRAAHIAVLDSELFLEKFLLVAGLNYFK", "length": 1475 }, "evidence": [ { "id": "FB:FBgn0052333", "url": "https://alliancegenome.org/gene/FB:FBgn0052333#orthology", "database": "AGR" }, { "id": "SGD:S000005585", "url": "https://alliancegenome.org/gene/SGD:S000005585#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0X9L1-1", "protein_name": "Family with sequence similarity 135 member A", "gene_name": "FAM135A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAVVVSLSELLRFLMKFYSSFTSSSAMAVNKLTKVLTSFDIFILINMSEVQAMVEFSVELHKFFNVDLFQRGFYQIRASMKIPPRIPHKLEASLLHATGADLAFPASIHDNIVYSKTFQILYKNEEVSVNDVMIFKIKMLLDERKIEESLNEMNFLLTLDLHFTDTDYSPDDLSTLQPISSRTLKLHFNLHRGLHHYVNVMFDYFHLSVISVIVHASLVALHQPLISFPRPVKNTWLNRNAPAQNRDSVIPSLESVVFGNNYTKQLSADGCSFVVSESFLSHAYNFHYTLCASLLLAFKGLHSYFLMITKELPSSHRIELAKASMQVLYERLLRRKFPRTQRDAYLENIDVEVRLSELCEEVKKMENPDELAELINMNLAQLCSLLMALWGQFLEVITLQEEVTALLAQEHHTLRVRRFAEAFFCLEHPRQAALAYQELHAQSHLQMCTAIKNTSFCSSLPPLPIECSELDGDTNSLPIIFEDRYLDSVTEDMDVPWLVVQNLPRSESNKLDKIEAEEGFVAGFTSPELKIRPAGASSLWHSENEKMLTKSLKGKNEDANKPKVKVTKLMKTMKPENTKKVVKQNSKDSVVLVGYKCLKSAALEDASKSPEGRPSCNTNEGLDPAVSGFPCDTKTCTRQVSQREFVCLSSGTEEKTAKIEGVQPSQGSPVHSENVAIFSRLTISQAGPGTVQADSALQPRDTLEGCHGGQPASLGVRTIEVKPSSKNPYEGEKVTVHIGSWAELPQDGVQGENLQTPNIQASESGNKLHSGEPVLEKEDVHEKSFQHTSDVLTKMKNNQPSLSTKESQLSVSGDVTKLPDVNVTYASSRFSDSGIESEPSSFATLPNPDQVFENVQGQSACNAERLFPQLLLKPDYAIKNALESHCTESTSAVSEIQSSLTSINSLPSDDDELSPDENSKITIVPECQLSDSKTVLDLGAIDLPKCDDSKKSSTNVQQHCVVFSGHSDKETLSIHSSVSGTKELLHLVVSDEVTSSDVKSNSLQADLGTTCTDSQVLERYCDTTEDAAKLHLEITCMGEPSVLSGPSSLNAGYEVEKPNEGKYNEPLELKEAVEELSAAKSDTGTDNPSPTSSTDIVKQGLVENYFGSRSSTDISDIWPMDNSNPVSPQKETYEKQIICSSQQDDEEEEDQEMIENGYYEETDYGILDGAAGAGQDPDLAEERALRSERIDSGHLRDGITVPPVCTPGCLSFPSSLRDSPCNVICSSRNKSDAITQQPGSTSYSSALPVSWYESSPKPQMLAFLQAKEELKQLKLPGFMYSDVFKLASSVPYFSMEEDDCSEEGIHLIVCVHGLDGNSADLRLVKTYIELGLPGGRIDFLMSERNQNDTFADFDSMTDRLLDEIIQYIQIYNLTLSKISFIGHSLGNLIIRSVLTRPRFKYYLNKLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSKKAGLHYFKNIVLVGSLQDRYVPYHSARIEMCKTALKDKQSGPIYAEMIQNLLLPVLQNKECNLVRYNVINALPNTADSLIGRAAHIAVLDSEIFLEKFFLVAALKYFQ", "length": 1572 }, "evidence": [ { "id": "A0A8M6Z9L3", "url": "https://omabrowser.org/oma/group/A0A8M6Z9L3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9RX27-1", "protein_name": "Family with sequence similarity 135 member A", "gene_name": "FAM135A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTEVQAMVEFSVELNKFYNVDLFQRGFYQIRASMKIPPRVPHRVEASLLHAAGMTLAFPASVHDSLICSKTFQILYKNEEVVLNDVMIFKVKMLLDEKKIEETLEEMNFLLSLDLHFTDGDYSADDLNALQLISSRTLKLHFSLQRGLHHHVNVMFDYFHLSVVSVTVHASLVALHQPLISFPRPVKTTWLNRNAPAQNKDSVIPTLESVVFGINYTKQLSPDGCSFVIADSFLRHAYRFHYTLCAALLLAFKGLHSYFIMVTEELPSCQKLELEEMDVEARLTELCEEVKKIENPDELAELINMNLAQLCSLLMALWGQFLEVITLHEELRLLLAQEHHTLRVRRFSEAFFCFEHPREAAIAYQELHAQSHLQMCTAIKNTSFCSSLPPLPIECSELDGDLNSLPIIFEDRYLDSVTEDLDAPWMGIQSLQRSESSRMDKCETEESTLAGLSSPELKIRPAGTSSFWSTEGEKQLTKSLKGKNEESNKSKVKVTKLMKTMKPENTKKLIKQNSKDLVVLVGYKCLKSTASNDLFKSFEGNPTHSQKEGLDPTIYGYNFDPKTYMRQTSQKEASYLPANTERTEQKSPDIENVQPDLFDPLNSGSLNLCANLSISGKLDISQDDSEIAQVEHSVASRSSSDDCHDRQSAPTSGVRTIEVKPCNKDCFSGEKVTVKIGPWTELQQDEIFVDNLQLPNFESLDSNGKSKPMEITLEKEALQEAKCHSVGESLAKLRNNQPASTREYHLVVSGDTIKLPDISATCASSRFSDSGVESEPSSVAAHPNPDIVFETVPGQGLFISERLFPQLLMKPDCNVKFSLGSHCTESTSAFSEIQSSLTSINSLPSDDELSPDENPKKSAVSECHLSDSKTVLNLGTTDVPKCDDRKKSSIILQQQSVIFSGHLDNETIEIHSLNSSTKDPLQFVFSDEDTSSDVKSSCSSKPNLDTVCKDSQSPDKSSDSVGTTVPLSSELACSGTPCVVSGSVSTRADSSEDRTVKRKNSDALNPKQMCSEAPAVKDETYLGTGDAFSASPDMVKQGLVENYFGCQSSTDVSDTCAISYSHSVSPQKETSGKEMSSPQRDQGKDEEEEEQDQQMVQNGYYEEADYSSLEAAGDAHCADGADLGGERLAKSERLAGDYLSDGITMPTVCTSGCLSFPSAPRESPCGVKYSSKSKCDAVTKQPSSASHSCTSSLSWYENSPKPQIQAFLQAKDELKQLKLPGFMYSDVPLLASSVPYFCVEEEEEDHCGNGVHLIVCVHGLDGNSADLRLVKTYIELGLPGERIDFLMSERNQNDTFADFDSMTDRLLDEIIQYIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLSRLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSNKAGLHYFRNVVLVGSLQDRYVPYHSARIEMCKTALKDKQSGQIYSEMIHNLLRPVLQSKDCNLVRYNVINALPNTADSLIGRAAHIAVLDSEIFLEKFFLVAALKYFQ", "length": 1518 }, "evidence": [ { "id": "A0A8M6Z9L3", "url": "https://omabrowser.org/oma/group/A0A8M6Z9L3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1LZ91-1", "protein_name": "Family with sequence similarity 135, member B", "gene_name": "Fam135b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQTESSSLHSACVHESVVHSRIFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQLKVDLHYTDSEQQLRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVALQQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTTSEGSFYVPSENCIQHAHKWHRDVCLLLLHAYRGLRLYFLVIMRDIPELPTMELEVLAVEETLSQLCSELQMLNNPEKIAEQISKDLAWLASHLMALWTQFLDTVTLHSHVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSMDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPVSGHNLSVYPNFEVPVTSPAIMKLKGKEKSVINQKSSSRKEAPLSTTEAPELGSDEDVIQCPEMEENVSTQNPMDVCSESQVYLSIGEFQNRAGIPEDECWTGPRPDAVKDSLTDVDICRRSPGPEEGHTPALTYIDVESSNKNYPRAEPVLGLNVQHEPRGSRDSYGIVKTMPSKVLAGISQNNSISVNQTAALELRTLGRGVGQEGKPVLLSLKLTPAEPCDPLSTGLREALDTKPSLPDPGEEPEDLSVLSGVIKRSASIISDSGIESEPSSVAWSEARSRALEIPSDRDILHQVVRRHAHHRNSLEGGHTESNTSLPSAIQASLSSISSLPFEDEERELALTKLTKSVSAPQISSPEDTAEDSDTIKNTAGFSEDLDLSSKDNSSSRYSSPSYSGSRVQDVRAGHSLADIAVASDRPQGPGYMDIHKGNENHPDLQGPCCLDAMAENIPHVETKGLNLKIPCTTVLENPKTRSFHRTAVETAKGKAKELSLSKHMLSNNSISEVRAASHHRVPEISCAPAVGAGHLHSTGVQNGSLSVNDTMTLNRRHNASPEAKHEAGTVCPTVTHTIASPVSRNQELKAGTSISGSHLNSTEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQSPAPITHQPLGSFGVVSTYSSELEEEVSERMFSFYQAKEKFKKELKIEGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "length": 1403 }, "evidence": [ { "id": "FB:FBgn0052333", "url": "https://alliancegenome.org/gene/FB:FBgn0052333#orthology", "database": "AGR" }, { "id": "SGD:S000005585", "url": "https://alliancegenome.org/gene/SGD:S000005585#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RTT1-1", "protein_name": "Family with sequence similarity 135 member A", "gene_name": "FAM135A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTEVQAMVEFSVELNKFYNVDLFQRGFYQIRASMKIPPRVPHRVEASLLHAAGMALAFPASVHDSLICSKTFQILYKNEEVVLNDVMIFKVKMLLDEKKIEETLEEMNFLLCLDLHFTDGDYSADDLNALQLISSRILKLHFSLHRGLHHHVNVMFDYFHLSVVSVTVHASLVALHQPLISFPRPVKTTWLNRNAPAQNKDSVIPTLESVVFGINYTKQLSPDGCSFVIADAFLHHAYHFHYTLCATLLLAFKGLHSYFITVTEELPSCQKLELEEMDVEARLTELCEEVKKIENPDELAELINMNLAQLCSLLMALWGQFLEAITLHEELRLLLAQEHHTLRVRRFSEAFFCFEHPREAAIAYEELHAQSHLQMCTAIKNTSFCSSLPPLPIECSELDGDLNSLPIIFEDRYLDSVTEDLDAPWMGIQNLQRSESTRMDKYDTEESSIAGLSSPELKVRPAGASSVWYTEGEKQLTKSLKGKNEESIKSRVKVTKLMKTMKPENTKKLIKQNSKDSVVLVGYKCLKSTASNDLSKCFEGNPSHSQKEGLDATICGYNFDLKTHIRQTSQKEASYLPTNTERTEQKSPDIENMQPDLFDPLNSGSLNLCANLSISGKLDMSQDDSEIAQVEYNVVPRSSSDDCHDHQTAPTSGAKTIQVKSCNKDPLSGEKITVKVGPWTELQQDEIFVDNLQLPNFESLESNGKSKSIEITLEKEAFQEAKCRAIGESLAKLRSNQPASSTRDYHVAVSGDTIRLPDGNATCTSSRFSDSGVESEPSSVATHPNPEAVFETVQGQGLYNNERLFPQLLMKPDCNVKFSLGSHCTESTSAFSEIQSSLTSINSLPSDDELSPDENPKKSVVPECHLSDSKTVLNVGTIDVPKGDDRKKSSIILQQQSVVFSQQLDNETIAVHSLNPSTKDPLQFVFSDEDTSSDVKSSFNSKPNLDTMCKDSQSPNKSSNSAGTEIILNSKLVSLGSPCVVSGSVSTSTEVSEDRTVERKNSDALNLKQIYSEALTVKNETHLGTSEPFSASPDMVKQGLVEDYFGCQSSTDISDTYAISYSNSVSPQKEISEKEISNLQQEQGKDEEEEEQDQQMVQNGYYEETDYSALDGTGNAHCIDRDALEEERLIKSEKINSDYLRDGITMPTVCTSGCLSFPSAPRESPCSVKYSSKSKCDAITKQPSSTSYSFTSSVSWYENSPKPQIQAFLQAKEELKHLKLPGFMYSEVPLLASSVPYFSVEEEDSSEDGVHLIVCVHGLDGNSADLRLVKTYIELGLPGGRIDFLMSERNQNDTFADFDSMTDRLLDEIIQYIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSNKAGLHYFRNVVLVGSLQDRYVPYHSARIEMCKTALKDKQSGQIYSEMIHNLLRPVLQSKDCNLVRYNVINALPNTADSLIGRAAHIAVLDSEIFLEKFFLVAALKYFQ", "length": 1517 }, "evidence": [ { "id": "A0A8M6Z9L3", "url": "https://omabrowser.org/oma/group/A0A8M6Z9L3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M9PGQ5-1", "protein_name": "DUF676 domain-containing protein", "gene_name": "CG9137", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGDLQATIEFVVELHKFFNVDLFQRGLYQVRCGLRVSPRLLVQVETSIPEASGPGKQNGHANGANATDHGSSDSERGELSPGEVPRLHESPPGGSCSSASVINGSGASRIFQILYRNEEVPLRDIIHFRSHLLVDSRHLKESIERAEFSLQLELWFGEQNGSSSLNGNGGGSGMGSFSGPASSALTLASTRNLQLNFHPGRGLHYHLPVLFDYFHLAAISVGIHASLVALHQPYIKKSVFSYMKFCAPRSSKPWSAGKLSCRGNTSPGPLEAVFFGPQIGGTTKCSGGPAGRLLQSRAIHREICSLLLGAIEQLKATLNEFSTVLPPSINSQIGSPPLRENDTGERLQLLLDQAKQLEAEEDFAIRANSDIAQLCAESIFWWRRVLLASRSSTAVHTLLARKHHILRVRRFAEGFFVLEQPRHAAAAGCPDQTNGSPSPGHCQGYVAIAELARRSRYLQSLPPLPVHCTPIDGDASSLPLIFEDRYVTTNSTYARRRSGSDPQLEDAVSVVGVQKKKVDKTHSSSSLNGIKDCLACHFDYDYPQTNGSGPAHPHAKCVITPRFALGGEVLQASLTIAPSKEAAPEAVAPPTLRHNLSRHSVTGLLEDLDLDSSLPARHSKSLDQLDGCEGLATNPVSTTNNHTLPRLQADDLMRNICEFRQRYGKFDYLHEIKLLNPPKQQQQAVPQQQQQCNNGYNSLPKSMVPPRNSYPPPPPSQHTTMPRSSSSQIPRAVEIARVRVSDIKEMLRQGQLRKESSSSESDMMQKLQMLSSNSVPFRLEGTSNNNTTSSDPNTSGFSESLPNLAPPPEFDSDSQLRRQRSNSTSSLSEESGWVSSRRSSLAISSPDTITSTGMTNRQRHTQLNLGMGMAMETRLNGEQLRLRLQKVLEQQQLQQQHPHKNRKRQAGTSSQSRTPARQQTEVHKKISSVTVNIKRERSRYQLDRLRHLPNGESTEVEEMEPPPRRNRHKTACEKSKSDFDITSLKDMQPLDAVCLPPPQQFQDQEQELALVLAPPPPDEFRDPPPEPAPAAPIAPVPPPAAALPPTGKTKIVACHLPPPLKERQPIGAIDNPVYHIYESLRPISTPAIFSNKPVLKSHSLAELKRPQNLPNHSINHHCKTHAINANGNVLENGLDHEQDEIKENSNGQVRTNKQGHGSNTNSKHKRKGQLASAVQEAPPSISLLEFEKYREEFRKQIKYQGSIYSDYVQLASELPYFYISDEYRAFSPNGMHLVICVHGLDGNSADLRLVRTYLELGLPGVNLEFLMSERNQGDTFSDFDTMTDRLVTEILYHIDSCALNPARISFVAHSLGTIIVRSALARPQMRPLLPRLHTFLSLSGPHLGTLYNTSGLVNMGMWFMQKWKKSGSLLQLCMRDTTDMRNSFLYRLSQRSTLHHFKNILLCGSSQDRYVPAHSARLELCKAAMRDSSSLGTIYREMVHNIIAPILARPELTLARFDVHHALPHTANTLIGRAAHIAVLDSELFIEKFMLIAGLKYFS", "length": 1499 }, "evidence": [ { "id": "RGD:1304927", "url": "https://alliancegenome.org/gene/RGD:1304927#orthology", "database": "AGR" }, { "id": "MGI:1915437", "url": "https://alliancegenome.org/gene/MGI:1915437#orthology", "database": "AGR" }, { "id": "HGNC:21084", "url": "https://alliancegenome.org/gene/HGNC:21084#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080130-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080130-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0052333", "url": "https://alliancegenome.org/gene/FB:FBgn0052333#orthology", "database": "AGR" }, { "id": "A0A8M6Z9L3", "url": "https://omabrowser.org/oma/group/A0A8M6Z9L3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P53118-1", "protein_name": "Putative lipase ROG1", "gene_name": "ROG1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSLTPTNEILFHYKSSVKVGELERYVITYHLYDGEEIPPDLNLNSLWLKVRNMNPLSYRAAYLMGPFMLYCDVKTAQYHHSQKIVASVDYPKFEPNVQTQQDFVAELSVHNIRQKYVWIADVMSQILFTTNTNVTYEVTIGTSKESVENPHDLPSHLGSYSPKLTVNRLTTLDLWNLPVQITTPQKKKHLVVLTHGLHSNVSTDLVYIMEQIYKAQKNYPHEQIVVKGYRGNVCQTEKGVKYLGTRLAEYIIQDLYDESIRKISFVGHSLGGLIQAFAIAYIYEVYPWFFKKVNPINFITLASPLLGIVTDNPAYIKVLLSFGVIGKTGQDLGLENDVEVGKPLLYLLSGLPLIEILRRFKRRTVYANAINDGIVPLYTASLLFLDYNDILEQLQKLKENSKKSPLINDASTPVNQDFFNKTFISPLTKMLSILAPQKFPTENGSEIPKVSFFESASSILLPPLPERAYIMDPDSRDPVIIHDKIYNEDDIPQSEFDIEDGFFGKKNILLQAFFAGKKERAKYRNLEETIARRWHEGMAWRKVVVALKPDAHNNIIVRRKFANAYGWPVIDHLIDVHFNGDDDDDNDENDDINSTQVVEPIQSVTEGKKKYRKAENIPQEYGWLNKVETNGVFDEGPTGMISTVGEIVEALAKRGFSAVIDRRNASEDPNDEVLRFEEMNSDLVQ", "length": 685 }, "evidence": [ { "id": "RGD:1304927", "url": "https://alliancegenome.org/gene/RGD:1304927#orthology", "database": "AGR" }, { "id": "MGI:1915437", "url": "https://alliancegenome.org/gene/MGI:1915437#orthology", "database": "AGR" }, { "id": "HGNC:21084", "url": "https://alliancegenome.org/gene/HGNC:21084#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q08448-1", "protein_name": "Lipid droplet phospholipase 1", "gene_name": "LPL1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTSDKHLFVLIHGLWGNYTHMESMRTILSTTLKKEDVNDDMIYFLPKQNAMFKTFDGIEIIGYRTLIEVCEFIRDYKDGKITKLSVMGYSQGGLVARFMIGKMLTEFKELFEDIEPQLFITMATPHLGVEFYNPTGIAYKSALYSALRTLGSTILGKSGREMFIANSSNNILVKLSQGEYLEALSLFKWRIAFANVKNDRTVAFYTAFITDCDPFIDFDNKLKYTFEEKIPGSGYKGILPKIVDLNALNVNSHAPTKPTKTYKKWGRTILIILVATFLILPIALVMNGLGTAYSYIVTCKYRKMLSNGILHNEVRGKLGLTEQLKGYVTDAYGSIINSALDMDANYEASNSNLVNEEELPWKEFIQKYTTINDGVWKSKFKKLPFDENRKVILRNLNKLKWIRVPIYIKAVNAHGVIVARRGMDENTAATGIACIEFTAQLLAYLMHKSN", "length": 450 }, "evidence": [ { "id": "RGD:1304927", "url": "https://alliancegenome.org/gene/RGD:1304927#orthology", "database": "AGR" }, { "id": "MGI:1915437", "url": "https://alliancegenome.org/gene/MGI:1915437#orthology", "database": "AGR" }, { "id": "HGNC:21084", "url": "https://alliancegenome.org/gene/HGNC:21084#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080130-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080130-1#orthology", "database": "AGR" }, { "id": "SGD:S000005585", "url": "https://alliancegenome.org/gene/SGD:S000005585#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q12103-1", "protein_name": "Putative lipase YDL109C", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEAGRSADEVLYHNQSSVKLGELERYVITYELYQGDSIPADITLDSLWVKIKNTTKLSYKPAYLLGPFILYCDVRAKDYESSYKIICSADKPVFQSNLQAQQKFIAELSLHHIKPRYVWIVDIVSQILFNKETKVTFEIVVGNSKASLKRKIRCNDSLPDKACNILHTGLSVHRLTTADIWKVPRPIDMSQKSHLVILTHGFQSNVSADMEYLMEEIYKAQMNNPNERLVIKGYMKNACETEKGIKFLGVGLANYIIDELYDDSVGKISFIGHSLGGLTQTFAICYIKTKYPYFFKKVEPINFISLASPLLGIATSTPNYVKMSLSMGIIGTTGQELGLKDGNYGDKPLLYLLSEESLISVLARFKRRTLYANAVNDGIVPLYSSSLLFLDYSQLLQKLGGQTTAPCDPLFQPEVSPIGELPNHSDVANDDDGINASSWNTFWKSKENNCDKKSKRLMNASVIKSMKSVLLSPCPDAKFFSDPDARVATIIHDKIYTEKNLPPPSPTLYEGTAAKEGETRKTRKEMEEIIARRWHKGMHWRKVVVLLKPDAHNNIIVRRRFSNAYGWPVVDHLVTAHFQRDDPIASPMQDKQFAEEDINMATGGVEPNKFYSWLTKIEDPSVYHGGIVSTASQLASSWISKHSSVTD", "length": 647 }, "evidence": [ { "id": "RGD:1304927", "url": "https://alliancegenome.org/gene/RGD:1304927#orthology", "database": "AGR" }, { "id": "MGI:1915437", "url": "https://alliancegenome.org/gene/MGI:1915437#orthology", "database": "AGR" }, { "id": "HGNC:21084", "url": "https://alliancegenome.org/gene/HGNC:21084#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q49AJ0-1", "protein_name": "Protein FAM135B", "gene_name": "FAM135B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEIQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIAGQTESSSLHSACVHDSTVHSRVFQILYRNEEVPINDAVVFRVHLLLGGERMEDALSEVDFQLKVDLHFTDSEQQLRDVAGAPMVSSRTLGLHFHPRNGLHHQVPVMFDYFHLSVISVTVHAALVALQQPLISFTRPGRGSWLGKGGPDTGQEQSIISLENLVFGAGYCKPTSSEGSFYITSENCMQHAHKWHRDLCLLLLHAYRGLRLHFLVIMRDIPELPHTELEALAVEETLSQLCSELQMLNNPEKIAEQISKDLAWLTSHMMTLWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPATGHNLSVYPNFDVPVTSPTIMNLKDKEDNCMVNSNLSFREDLVLSTIKPSQMDSDEEVIRCPEPGENVATQNHMDMCSESQVYISIGEFQNKAGVPEDECWTGQTSDAGTYPVADVDTSRRSPGPEDGQAPVLTYIDVKSSNKNPSRAEPLVAFNAQHESRSSRDKYGLDRTGLSKVVVGGSHQNAISSDKTTLHELSTLGKGIDQEGKMVLLSLKLTPSEPCDPLSSTLREPLDIRSSLKDSHTEEQEELSVLSGVIKRSSSIISDSGIESEPSSVAWSEARSRALELPSDREVLHPFVRRHALHRNSLEGGHTESNTSLPSGIQASLTSISSLPFEEDEREVALTKLTKSVSAPHISSPEEAAEDADTKQQDGGFAEPSDMHSKSQGSPGSCSQLCGDSGTDAGADHPLVEIVLDADNQQGPGYIDIPKGKGKQFDAQGHCLPDGRTENTPGVETKGLNLKIPRVIALENPRTRSLHRALEETPKGMPKDLNVGQQALSNSGISEVEGLSQHQVPELSCTSAADAINRNSTGQQSQSGSPCIMDDTAFNRGVNAFPEAKHKAGTVCPTVTHSVHSQVLKNQELKAGTSIMGSHLTSAETFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGFSSKQTLFPITHQPLGSFGVVSTHSSTLDEEVSERMFSFYQAKEKFKKELKIEGFLYSDLTVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQMDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "length": 1406 }, "evidence": [ { "id": "FB:FBgn0052333", "url": "https://alliancegenome.org/gene/FB:FBgn0052333#orthology", "database": "AGR" }, { "id": "SGD:S000005585", "url": "https://alliancegenome.org/gene/SGD:S000005585#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NS59-1", "protein_name": "Protein FAM135A", "gene_name": "Fam135a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEVQAMVEFSVELNKFYNVDLFQRGFYQIRASMKIPARIPHRVEASLLHATGMTLAFPASVHDALVCSKTFQILYKNEEVVLNDVMIFKVKMLLDERKIEETLEEISFLLSLGLHFTDGDYSADDLNALQLISSRTLKLHYSICRGLHHHANVMFDYFHLSVVSVTVHASLVALHQPLISFPRPVKTTWLNRNAPAQSKDSAIPTLESVVFGINYTKQLSPDGCSFLIAESFLHHAYHFHYTLCATLLLAFKGLHSYFITVTEEIPSCQKLDLEEMDVEARLTELCEEVKKVENPDELAELINMNLAQLCSLLMALWGQFLEAITLHEDLRVLLAQEHHTLRVRRFSEAFFCFEHPREAAIAYQELHAQSHLQMCTAIKNTSFCSSLPPLPIECSELDGDLNSLPIIFEDRYLDSVIEDLDAPWMGIQSLQISEASKTDKHETEESSVVGLSSPELKVRPAVASSNCYTEGEKQLTKSLKGKNEESNKSKVKVTKLMKTMKPENTKKLIKQNSKDSVVLVSYKCLKTTASSDFTKCLEGSPSHSQKEGLDPTLCAGNFDPKTYTRQPSQKEASSLSANTDRSEHKSPDTENMQPDQFELLNSGSLNLCANLSISGKLAISQDNSDIPDTEHNLASTSSSNDCHDYQTTPSSGVRTLEVKSSSKESFNGEKITVKIGPWTELQEAELFVDNLLPDFEALDSNDKPKSIDIPLERDALQETKCHSTEESLTKFRSNLPAPSTKEYHVAVSSDTIKLPDTNATYASSRFSDSGVESEPSSFATHPNPEIAFETLQGPGPCNNERLFPQLLMKPDHNVKFSLGSHCTESTSALSEIQSSLTSINSLPSDDELSPDDNCKKSAVPDCHLSDSKTVFNLGTMDLPKCDDTKKSSIILQQQSVVFSGHLDNDTLAMHSLDLSTEDPLRLVFLDEDASSGVRSSWGSKPHLDAPFTGPQSQGTSSNNSTESVPTLNSKLICLGSPCVVSGSVCTDAGLSADRTVEGKSGEPLNHKQVCSAAPVVESDPLSSSTDVVKQGLVENYFGSQSTTDVSDACAITCHSPVSSQETCDKGISDLQQEQGKEEEEEDQEMVQNGYHEETDFSATDGTVSVHYISGNELGEGRHEQSEKLSSNYLSAGVTVPAVCTSGCLSFPSALRESPCVKYSSRSKVDAITKQPSSISYNFSSSTSWYENSPKPQIHAFLQAKEELKQLRLPGFMYSDVPLLASSAPYFSMDEEDGSEDGVHLIVCVHGLDGNSADLRLVKTYIELGLPGGRVDFLMSERNQNDTFADFDCMTDRLLDEIIQYIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLSKLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSNKAGLHYFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQSGQIYSEMIHNLLRPVLQSKGCNLVRYNVINALPNTADSLIGRAAHIAVLDSEIFLEKFFLVAALKYFQ", "length": 1506 }, "evidence": [ { "id": "RGD:1304927", "url": "https://alliancegenome.org/gene/RGD:1304927#orthology", "database": "AGR" }, { "id": "MGI:1915437", "url": "https://alliancegenome.org/gene/MGI:1915437#orthology", "database": "AGR" }, { "id": "HGNC:21084", "url": "https://alliancegenome.org/gene/HGNC:21084#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080130-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080130-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0052333", "url": "https://alliancegenome.org/gene/FB:FBgn0052333#orthology", "database": "AGR" }, { "id": "SGD:S000005585", "url": "https://alliancegenome.org/gene/SGD:S000005585#orthology", "database": "AGR" }, { "id": "A0A8M6Z9L3", "url": "https://omabrowser.org/oma/group/A0A8M6Z9L3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAI6-1", "protein_name": "Protein FAM135B", "gene_name": "Fam135b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEVQGTVEFSVELHKFYNVDLFQRGYYQIRVTLKVSSRIPHRLSASIVGQSESSSLHSACVHESAVHSRVFQILYRNEEVSINDAMLFRVHLLLDGERVEDALSEVEFQLKVDLHFTDSEQQLRDVTGTPMISSRTLGLHFHPRRGLHHQVPVMFDYFHLSVISVAIHAALVALQQPLISFTRPGRGSWLGKGGPDTGPEQPTISLENLVFGAGYCKPTSSEGSFYVPSENCIQHAHKWHRDLCLLLLHAYQGLRLYFLVIMRDIPELPTMELEALAVEETLSQLCSELQMLNNPEKIAEQISKDLAWLASHLMALWTQFLDTVTLHSQVTTYLTQEHHTLRVRRFSEAFFYMEHQKLAVLTFQENLIQTHSQLSLDIRNSEYLTSMPPLPAECLDIDGDWNTLPVIFEDRYVDCPVSGHNLSVYPNFDVPVTSPAIMNLKGKEKNLINQNSSSRKDIPLSTTEAPQLGSDEDVTRRPEVQENVSTWNPIDVCSESQVYLTIGEFQNRAGIPEDECWTGPRPDAVKDSLTDTDICSRSPGPDEGQTPALTYIDVQSSNKYCPRAELVQGINVQHEHRSSRESYGIVKTVPSKVVAGTSQNNSTSLNQTAALELRTLGRGVNQDGKPVLLSLKLTPAEPCDPPSTALREALDTKPSQPDHAEEPEDLSALSGVIKRSASIISDSGIESEPSSVAWSEARSRALELPSDRDVLHQVVRRHAHHRNSLEGGHTESNTSLPSGIQASLSSISSLPFEEEERELALNKLTKSVSAPQISSPEESAEGADTIKNTAGFSEDLDPSSKENSPPRHTSLSYGGSRVQDVRAGHSLADIALDSDRPQGPGYMDIPNDKGNHPELQEPCCLDGMAETPLHVETKGLNLKIPCTIVLENSKSRSFHRAAGETAKGKPEELSMSKCVLSNNSISEVRAASHHRVPEISCSPAVEAVNLNSTGVQNSSLSVNDTMTLNRRHNASLEAKHEAGTVCPTVTHTIASQVSRNQELKTGTSISGSHLNSTEAFTLDSLKAVEVVNLSVSCTATCLPFSSVPKETPARAGLSSKQNPAPITHQPLGSFGVVSTYSSKLEEEVSERMFSFYQAKEKFKKELKIEGFLYSDLSVLASDIPYFPPEEEEENLEDGIHLVVCVHGLDGNSADLRLVKTFIELGLPGGKLDFLMSEKNQTDTFADFDTMTDRLLDEIIQHIQLYNLSISRISFIGHSLGNIIIRSVLTRPRFRYYLNKLHTFLSLSGPHLGTLYNNSTLVSTGLWLMQKLKKSGSLLQLTFRDNADLRKCFLYQLSQKTGLQYFKNVVLVASPQDRYVPFHSARIEMCKTALKDRHTGPVYAEMINNLLGPLVEAKDCTLIRHNVFHALPNTANTLIGRAAHIAVLDSELFLEKFFLVAGLNYFK", "length": 1403 }, "evidence": [ { "id": "FB:FBgn0052333", "url": "https://alliancegenome.org/gene/FB:FBgn0052333#orthology", "database": "AGR" }, { "id": "SGD:S000005585", "url": "https://alliancegenome.org/gene/SGD:S000005585#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2D6-1", "protein_name": "Protein FAM135A", "gene_name": "FAM135A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEVQAMVEFSVELNKFYNVDLFQRGFYQIRASMKIPSRIPHRVEASLLHATGMTLAFPASVHDSLICSKTFQILYKNEEVVLNDVMIFKVKMLLDERKIEETLEEMNFLLSLDLHFTDGDYSADDLNALQLISSRTLKLHFSPHRGLHHHVNVMFDYFHLSVVSVTVHASLVALHQPLISFPRPVKTTWLNRNAPAQNKDSVIPTLESVVFGINYTKQLSPDGCSFIIADSFLHHAYRFHYTLCATLLLAFKGLHSYFITVTEEIPSCQKLELEEMDVEARLTELCEEVKKIENPDELAELINMNLAQLCSLLMALWGQFLEVITLHEELRILLAQEHHTLRVRRFSEAFFCFEHPREAAIAYQELHAQSHLQMCTAIKNTSFCSSLPPLPIECSELDGDLNSLPIIFEDRYLDSVTEDLDAPWMGIQNLQRSESSKMDKYETEESSVAGLSSPELKVRPAGASSIWYTEGEKQLTKSLKGKNEESNKSKVKVTKLMKTMKSENTKKLIKQNSKDSVVLVGYKCLKSTASNDLIKCFEGNPSHSQKEGLDPTICGYNFDPKTYMRQTSQKEASCLPTNTERTEQKSPDIENVQPDQFDPLNSGNLNLCANLSISGKLDISQDDSEITQMEHNLASRRSSDDCHDHQTTPSLGVRTIEIKPSNKDPFSGENITVKLGPWTELRQEEILVDNLLPNFESLESNGKSKSIEITFEKEALQEAKCLSIGESLTKLRSNLPAPSTKEYHVVVSGDTIKLPDISATYASSRFSDSGVESEPSSFATHPNTDLVFETVQGQGPCNSERLFPQLLMKPDYNVKFSLGNHCTESTSAISEIQSSLTSINSLPSDDELSPDENSKKSVVPECHLNDSKTVLNLGTTDLPKCDDTKKSSITLQQQSVVFSGNLDNETVAIHSLNSSIKDPLQFVFSDEETSSDVKSSCSSKPNLDTMCKGFQSPDKSNNSTGTAITLNSKLICLGTPCVISGSISSNTDVSEDRTMKKNSDVLNLTQMYSEIPTVESETHLGTSDPFSASTDIVKQGLVENYFGSQSSTDISDTCAVSYSNALSPQKETSEKEISNLQQEQDKEDEEEEQDQQMVQNGYYEETDYSALDGTINAHYTSRDELMEERLTKSEKINSDYLRDGINMPTVCTSGCLSFPSAPRESPCNVKYSSKSKFDAITKQPSSTSYNFTSSISWYESSPKPQIQAFLQAKEELKLLKLPGFMYSEVPLLASSVPYFSVEEEDGSEDGVHLIVCVHGLDGNSADLRLVKTYIELGLPGGRIDFLMSERNQNDTFADFDSMTDRLLDEIIQYIQIYSLTVSKISFIGHSLGNLIIRSVLTRPRFKYYLNKLHTFLSLSGPHLGTLYNSSALVNTGLWFMQKWKKSGSLLQLTCRDHSDPRQTFLYKLSNKAGLHYFKNVVLVGSLQDRYVPYHSARIEMCKTALKDKQSGQIYSEMIHNLLRPVLQSKDCNLVRYNVINALPNTADSLIGRAAHIAVLDSEIFLEKFFLVAALKYFQ", "length": 1515 }, "evidence": [ { "id": "RGD:1304927", "url": "https://alliancegenome.org/gene/RGD:1304927#orthology", "database": "AGR" }, { "id": "MGI:1915437", "url": "https://alliancegenome.org/gene/MGI:1915437#orthology", "database": "AGR" }, { "id": "HGNC:21084", "url": "https://alliancegenome.org/gene/HGNC:21084#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080130-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080130-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0052333", "url": "https://alliancegenome.org/gene/FB:FBgn0052333#orthology", "database": "AGR" }, { "id": "SGD:S000005585", "url": "https://alliancegenome.org/gene/SGD:S000005585#orthology", "database": "AGR" }, { "id": "A0A8M6Z9L3", "url": "https://omabrowser.org/oma/group/A0A8M6Z9L3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9L3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1119, "end_pos": 1121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1144, "end_pos": 1146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1194, "end_pos": 1196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 869, "end_pos": 871, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z9L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9L3" }, { "id": "PF05057", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05057" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF676", "eco_id": "ECO_0000259", "start_pos": 1076, "end_pos": 1268, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1017 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1119, "end_pos": 1121 }, { "start_pos": 1144, "end_pos": 1146 }, { "start_pos": 1194, "end_pos": 1196 }, { "start_pos": 464, "end_pos": 466 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 604, "end_pos": 606 }, { "start_pos": 869, "end_pos": 871 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 } ], "sort_fields": [ "start_pos", "end_pos", "kinase_uniprot_canonical_ac", "kinase_gene_name", "residue", "comment", "site_lbl" ] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 1271 }, { "field": "total_sites", "count": 848 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 1266 }, { "field": "total_sites", "count": 845 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 } ], "sort_fields": [ "start_pos", "end_pos", "subjects_tested", "subjects_positive", "frequency", "sequence_org", "sequence_mut", "comment", "chr_id", "chr_pos", "ref_nt", "alt_nt", "minor_allelic_frequency", "site_lbl" ] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M6Z2T6-1", "uniprot_ac": "A0A8M6Z2T6", "uniprot_id": "A0A8M6Z2T6_DANRE", "mass": { "chemical_mass": 117468.0, "monoisotopic_mass": 117468.0 }, "refseq": { "ac": "NP_001352143", "name": "cordon-bleu protein-like 1b", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352143" }, "gene_names": [ { "name": "cobll1b", "type": "recommended", "evidence": [ { "id": "A0A8M6Z2T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6" } ] }, { "name": "cobll1b", "type": "synonym", "evidence": [ { "id": "NP_001352143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352143" } ] }, { "name": "sb:cb819", "type": "synonym", "evidence": [ { "id": "NP_001352143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352143" }, { "id": "A0A8M6Z2T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6" } ] }, { "name": "si:ch73-76o7.1", "type": "synonym", "evidence": [ { "id": "NP_001352143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352143" }, { "id": "A0A8M6Z2T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6" } ] } ], "protein_names": [ { "name": "Cordon-bleu protein-like 1b", "type": "synonym", "evidence": [ { "id": "A0A8M6Z2T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6/entry#names_and_taxonomy" } ] }, { "name": "cobll1", "type": "synonym", "evidence": [ { "id": "NP_001352143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352143" } ] }, { "name": "cordon-bleu protein-like 1b", "type": "synonym", "evidence": [ { "id": "NP_001352143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352143" } ] }, { "name": "cordon-bleu protein-like 1", "type": "synonym", "evidence": [ { "id": "NP_001352143", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352143" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01017177.1, SRR26395039.294039.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476730, SAMEA4476733 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1. On Aug 8, 2018 this sequence version replaced XP_009303254.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001352143", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352143" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cobll1b", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120313-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120313-6", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100332245", "url": "https://www.ncbi.nlm.nih.gov/gene/100332245", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039895", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039895", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100332245", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100332245", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M3BCN4", "url": "https://www.orthodb.org/?gene=A0A8M3BCN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z2T6", "url": "https://www.orthodb.org/?gene=A0A8M6Z2T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21557", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21557", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21557:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21557:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001352143", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352143", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3BCN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BCN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3BCN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BCN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2T6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QBM4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QBM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TWP4", "url": "https://www.uniprot.org/uniprotkb/A0AB32TWP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TWP4-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TWP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U116", "url": "https://www.uniprot.org/uniprotkb/A0AB32U116", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U116-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32U116-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GD15", "url": "https://www.uniprot.org/uniprotkb/A0AC58GD15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GD15-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GD15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GD20", "url": "https://www.uniprot.org/uniprotkb/A0AC58GD20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GD20-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GD20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GD24", "url": "https://www.uniprot.org/uniprotkb/A0AC58GD24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GD24-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GD24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120313-6", "url": "https://zfin.org/ZDB-GENE-120313-6", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTADSRAKLQRRSSARDCRAAAGMDGNAHNRPPDRRRSTKSKAPPPPVLTGLDAPLLSHKLQAFPHPAMEQTESLLEQELTLTVILPGGAEKITTVHGSKPMMDLLVMLCAQHHLNPSGHTLELITTNRNHVKFKPNALIGALEADKILLKPKGMEDKSKKTGPHMPEATVRLVINYRKTQKTILRVSPRVPLRELLPAICQKCEFDPQTTLLSPSVQSEDTLDLSGSLNDFGLREVYARDTRVISPVSPISPVSLPPSPTRSEIFYHGKEKSLREKDNKRRFSLFRRGSKKQSEQSMTVSAPASPVHRKQRPVSMSSFSTHVPLSYDCNTMPSDTPKKRRAPLPPSMMSQSMPSDLSQTQTTVHPDGNQNLSSLSRASSTESSFKKSSTKRKAPPPPVMISTDTTHQDTTDSSMTESAVTSPLEEIKEQEEMSVGAGVNVEDETLEDNSSLNMSANISLDSGRAGTATPSQDSVTLESGTPRDDPVCDLSTDAEVAEGTVNGEMKADQTRSSHITSEDKDPGKTEQLIQPSESGPVLEEVTVSNTSLPQRSECGIQTSQTDLQVQCFDSDTAISSPESSCSIYAEAQTSKTIPNTSSLTHTETQTQVQSSNEPSSLCTEFSTSTIGLKKDMATSTDELQPSIQQSKDLTSTSKPASVSYVTDAEPKPKPSNEHTRGYIPKVGMTTYTIVPQKSLEKLHSLEIEMTLEPKVDCKPNVSNGTVTLNGHQNAFAQTNQCTSPPATNSTNLSTNLSTKPTSLSANTTYSSTKPTSSSTSPTYLSTNPTNWSTNPINSSTSPTYLSTNPSNSSTNPTNSSTKQTNSSTNPTNSSSVDERIDSVSLKDKKVPPATRPKPASFRVPQHKRMSGDYVSSAAVRRASIGSSSSSSSCCSSPAARPKESLSSPQSDVFPAMEIFPPPPPPVQWEEEQSQSTSAKSLPQNEEIDAALPEAPKIPPSSFLSRQKSLPTNPAPSLSLEKLRSFAAPKPYSPSSPSRFAQAVSSAVKRSQSLSHHAPVQETRTHTLTKQRPIRESPEPPTSTVADNGDREPETQTADTDPVMGTCKIGNTQASPGSEASSQEVSDVFHSAEE", "length": 1089, "header": "tr|A0A8M6Z2T6-1|A0A8M6Z2T6_DANRE Isoform 1 of Cordon-bleu protein-like 1b OS=Danio rerio OX=7955 GN=cobll1b PE=4 SV=1 CANONICAL=A0A8M6Z2T6-1" }, "isoforms": [ { "isoform_ac": "A0A8M3BCN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6/entry#A0A8M3BCN4-1", "sequence": { "sequence": "MTADSRAKLQRRSSARDCRAAAGMDGNAHNRPPDRRRSTKSKAPPPPVLTGLDAPLLSHKLQAFPHPAMEQTESLLEQELTLTVILPGGAEKITTVHGSKPMMDLLVMLCAQHHLNPSGHTLELITTNRNHVKFKPNALIGALEADKILLKPKGMEDKSKKTGPHMPEATVRLVINYRKTQKTILRVSPRVPLRELLPAICQKCEFDPQTTLLSPSVQSEDTLDLSGSLNDFGLREVYARDTRVISPVSPISPVSLPPSPTRSEIFYHGKEKSLREKDNKRRFSLFRRGSKKQSEQSMTVSAPASPVHRKQRPVSMSSFSTHVPLSYDCNTMPSDTPKKRRAPLPPSMMSQSMPSDLSQTQTTVHPDGNQNLSSLSRASSTESSFKKSSTKRKAPPPPVMISTDTTHQDTTDSSMTESAVTSPLEEIKEQEEMSVGAGVNVEDETLEDNSSLNMSANISLDSGRAGTATPSQDSVTLESGTPRDDPVCDLSTDAEVAEGTVNGEMKADQTRSSHITSEDKDPGKTEQLIQPSESGPVLEEVTVSNTSLPQRSECGIQTSQTDLQVQCFDSDTAISSPESSCSIYAEAQTSKTIPNTSSLTHTETQTQVQSSNEPSSLCTEFSTSTIGLKKDMATSTDELQPSIQQSKDLTSTSKPASVSYVTDAEPKPKPSNEHTRGYIPKVGMTTYTIVPQKSLEKLHSLEIEMTLEPKVDCKPNVSNGTVTLNGHQNAFAQTNQCTSPPATNSTNLSTNLSTKPTSLSANTTYSSTKPTSSSTSPTYLSTNPTNWSTNPINSSTSPTYLSTNPSNSSTNPTNSSTKQTNSSTNPTNSSSVDERIDSVSLKDKKVPPATRPKPASFRVPQHKRMSGDYVSSAAVRRASIGSSSSSSSCCSSPAARPKESLSSPQSDVFPAMEIFPPPPPPVQWEEEQSQSTSAKSLPQNEEIDAALPEAPKIPPSSFLSRQKSLPTNPAPSLSLEKLRSFAAPKPYSPSSPSRFAQAVSSAVKRSQSLSHHAPVQETRTHTLTKQRPIRESPEPPTSTVADNGDREPETQTADTDPVMGTWV", "length": 1063, "header": "tr|A0A8M3BCN4-1|A0A8M6Z2T6_DANRE Computationally mapped isoform of Cordon-bleu protein-like 1b OS=Danio rerio OX=7955 GN=cobll1b PE=4 SV=1 CANONICAL=A0A8M6Z2T6-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z2T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6/entry#A0A8M6Z2T6-1", "sequence": { "sequence": "MTADSRAKLQRRSSARDCRAAAGMDGNAHNRPPDRRRSTKSKAPPPPVLTGLDAPLLSHKLQAFPHPAMEQTESLLEQELTLTVILPGGAEKITTVHGSKPMMDLLVMLCAQHHLNPSGHTLELITTNRNHVKFKPNALIGALEADKILLKPKGMEDKSKKTGPHMPEATVRLVINYRKTQKTILRVSPRVPLRELLPAICQKCEFDPQTTLLSPSVQSEDTLDLSGSLNDFGLREVYARDTRVISPVSPISPVSLPPSPTRSEIFYHGKEKSLREKDNKRRFSLFRRGSKKQSEQSMTVSAPASPVHRKQRPVSMSSFSTHVPLSYDCNTMPSDTPKKRRAPLPPSMMSQSMPSDLSQTQTTVHPDGNQNLSSLSRASSTESSFKKSSTKRKAPPPPVMISTDTTHQDTTDSSMTESAVTSPLEEIKEQEEMSVGAGVNVEDETLEDNSSLNMSANISLDSGRAGTATPSQDSVTLESGTPRDDPVCDLSTDAEVAEGTVNGEMKADQTRSSHITSEDKDPGKTEQLIQPSESGPVLEEVTVSNTSLPQRSECGIQTSQTDLQVQCFDSDTAISSPESSCSIYAEAQTSKTIPNTSSLTHTETQTQVQSSNEPSSLCTEFSTSTIGLKKDMATSTDELQPSIQQSKDLTSTSKPASVSYVTDAEPKPKPSNEHTRGYIPKVGMTTYTIVPQKSLEKLHSLEIEMTLEPKVDCKPNVSNGTVTLNGHQNAFAQTNQCTSPPATNSTNLSTNLSTKPTSLSANTTYSSTKPTSSSTSPTYLSTNPTNWSTNPINSSTSPTYLSTNPSNSSTNPTNSSTKQTNSSTNPTNSSSVDERIDSVSLKDKKVPPATRPKPASFRVPQHKRMSGDYVSSAAVRRASIGSSSSSSSCCSSPAARPKESLSSPQSDVFPAMEIFPPPPPPVQWEEEQSQSTSAKSLPQNEEIDAALPEAPKIPPSSFLSRQKSLPTNPAPSLSLEKLRSFAAPKPYSPSSPSRFAQAVSSAVKRSQSLSHHAPVQETRTHTLTKQRPIRESPEPPTSTVADNGDREPETQTADTDPVMGTCKIGNTQASPGSEASSQEVSDVFHSAEE", "length": 1089, "header": "tr|A0A8M6Z2T6-1|A0A8M6Z2T6_DANRE Isoform 1 of Cordon-bleu protein-like 1b OS=Danio rerio OX=7955 GN=cobll1b PE=4 SV=1 CANONICAL=A0A8M6Z2T6-1" }, "locus": {} }, { "isoform_ac": "A0A8M9QBM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6/entry#A0A8M9QBM4-1", "sequence": { "sequence": "MTADSRAKLQRRSSARDCRAAAGMDGNAHNRPPDRRRSTKSKAPPPPVLTGLDAPLLSHKLQAFPHPAMEQTESLLEQELTLTVILPGGAEKITTVHGSKPMMDLLVMLCAQHHLNPSGHTLELITTNRNHVKFKPNALIGALEADKILLKPKGMEDKSKKTGPHMPEATVRLVINYRKTQKTILRVSPRVPLRELLPAICQKCEFDPQTTLLSPSVQSEDTLDLSGSLNDFGLREVYARDTRVISPVSPISPVSLPPSPTRSEIFYHGKEKSLREKDNKRRFSLFRRGSKKQSEQSMTVSAPASPVHRKQRPVSMSSFSTHVPLSYDCNTMPSDTPKKRRAPLPPSMMSQSMPSDLSQTQTTVHPDGNQNLSSLSRASSTESSFKKSSTKRKAPPPPVMISTDTTHQDTTDSSMTESAVTSPLEEIKEQEEMSVGAGVNVEDETLEDNSSLNMSANISLDSGRAGTATPSQDSVTLESGTPRDDPVCDLSTDAEVAEGTVNGEMKADQTRSSHITSEDKDPGKTEQLIQPSESGPVLEEVTVSNTSLPQRSECGIQTSQTDLQVQCFDSDTAISSPESSCSIYAEAQTSKTIPNTSSLTHTETQTQVQSSNEPSSLCTEFSTSTIGLKKDMATSTDELQPSIQQSKDLTSTSKPASVSYVTDAEPKPKPSNEHTRGYIPKVGMTTYTIVPQKSLEKLHSLEIEMTLEPKVDCKPNVSNGTVTLNGHQNAFAQTNQCTSPPATNSTNLSTNLSTKPTSLSANTTYSSTKPTSSSTSPTYLSTNPTNWSTNPINSSTSPTYLSTNPSNSSTNPTNSSTKQTNSSTNPTNSSSVDERIDSVSLKDKKVPPATRPKPASFRVPQHKRMSGDYVSSAAVRRASIGSSSSSSSCCSSPAARPKESLSSPQSDVFPAMEIFPPPPPPVQWEEEQSQSTSAKSLPQNEEIDAALPEAPKIPPSSFLSRQKSLPTNPAPSLSLEKLRSFAAPKPYSPSSPSRFAQAVSSAVKRSQSLSHHAPVQETRTHTLTKQRPIRESPEPPTSTGSEASSQEVSDVFHSAEE", "length": 1057, "header": "tr|A0A8M9QBM4-1|A0A8M6Z2T6_DANRE Computationally mapped isoform of Cordon-bleu protein-like 1b OS=Danio rerio OX=7955 GN=cobll1b PE=4 SV=1 CANONICAL=A0A8M6Z2T6-1" }, "locus": {} }, { "isoform_ac": "A0AB32TWP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6/entry#A0AB32TWP4-1", "sequence": { "sequence": "MTGVDLYLQDRRSTKSKAPPPPVLTGLDAPLLSHKLQAFPHPAMEQTESLLEQELTLTVILPGGAEKITTVHGSKPMMDLLVMLCAQHHLNPSGHTLELITTNRNHVKFKPNALIGALEADKILLKPKGMEDKSKKTGPHMPEATVRLVINYRKTQKTILRVSPRVPLRELLPAICQKCEFDPQTTLLSPSVQSEDTLDLSGSLNDFGLREVYARDTRVISPVSPISPVSLPPSPTRSEIFYHGKEKSLREKDNKRRFSLFRRGSKKQSEQSMTVSAPASPVHRKQRPVSMSSFSTHVPLSYDCNTMPSDTPKKRRAPLPPSMMSQSMPSDLSQTQTTVHPDGNQNLSSLSRASSTESSFKKSSTKRKAPPPPVMISTDTTHQDTTDSSMTESAVTSPLEEIKEQEEMSVGAGVNVEDETLEDNSSLNMSANISLDSGRAGTATPSQDSVTLESGTPRDDPVCDLSTDAEVAEGTVNGEMKADQTRSSHITSEDKDPGKTEQLIQPSESGPVLEEVTVSNTSLPQRSECGIQTSQTDLQVQCFDSDTAISSPESSCSIYAEAQTSKTIPNTSSLTHTETQTQVQSSNEPSSLCTEFSTSTIGLKKDMATSTDELQPSIQQSKDLTSTSKPASVSYVTDAEPKPKPSNEHTRGYIPKVGMTTYTIVPQKSLEKLHSLEIEMTLEPKVDCKPNVSNGTVTLNGHQNAFAQTNQCTSPPATNSTNLSTNLSTKPTSLSANTTYSSTKPTSSSTSPTYLSTNPTNWSTNPINSSTSPTYLSTNPSNSSTNPTNSSTKQTNSSTNPTNSSSVDERIDSVSLKDKKVPPATRPKPASFRVPQHKRMSGDYVSSAAVRRASIGSSSSSSSCCSSPAARPKESLSSPQSDVFPAMEIFPPPPPPVQWEEEQSQSTSAKSLPQNEEIDAALPEAPKIPPSSFLSRQKSLPTNPAPSLSLEKLRSFAAPKPYSPSSPSRFAQAVSSAVKRSQSLSHHAPVQETRTHTLTKQRPIRESPEPPTSTVADNGDREPETQTADTDPVMGTCKIGNTQASPGSEASSQEVSDVFHSAEE", "length": 1064, "header": "tr|A0AB32TWP4-1|A0A8M6Z2T6_DANRE Computationally mapped isoform of Cordon-bleu protein-like 1b OS=Danio rerio OX=7955 GN=cobll1b PE=4 SV=1 CANONICAL=A0A8M6Z2T6-1" }, "locus": {} }, { "isoform_ac": "A0AB32U116-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6/entry#A0AB32U116-1", "sequence": { "sequence": "MYQISGIFRLFRGYLKRRSTKSKAPPPPVLTGLDAPLLSHKLQAFPHPAMEQTESLLEQELTLTVILPGGAEKITTVHGSKPMMDLLVMLCAQHHLNPSGHTLELITTNRNHVKFKPNALIGALEADKILLKPKGMEDKSKKTGPHMPEATVRLVINYRKTQKTILRVSPRVPLRELLPAICQKCEFDPQTTLLSPSVQSEDTLDLSGSLNDFGLREVYARDTRVISPVSPISPVSLPPSPTRSEIFYHGKEKSLREKDNKRRFSLFRRGSKKQSEQSMTVSAPASPVHRKQRPVSMSSFSTHVPLSYDCNTMPSDTPKKRRAPLPPSMMSQSMPSDLSQTQTTVHPDGNQNLSSLSRASSTESSFKKSSTKRKAPPPPVMISTDTTHQDTTDSSMTESAVTSPLEEIKEQEEMSVGAGVNVEDETLEDNSSLNMSANISLDSGRAGTATPSQDSVTLESGTPRDDPVCDLSTDAEVAEGTVNGEMKADQTRSSHITSEDKDPGKTEQLIQPSESGPVLEEVTVSNTSLPQRSECGIQTSQTDLQVQCFDSDTAISSPESSCSIYAEAQTSKTIPNTSSLTHTETQTQVQSSNEPSSLCTEFSTSTIGLKKDMATSTDELQPSIQQSKDLTSTSKPASVSYVTDAEPKPKPSNEHTRGYIPKVGMTTYTIVPQKSLEKLHSLEIEMTLEPKVDCKPNVSNGTVTLNGHQNAFAQTNQCTSPPATNSTNLSTNLSTKPTSLSANTTYSSTKPTSSSTSPTYLSTNPTNWSTNPINSSTSPTYLSTNPSNSSTNPTNSSTKQTNSSTNPTNSSSVDERIDSVSLKDKKVPPATRPKPASFRVPQHKRMSGDYVSSAAVRRASIGSSSSSSSCCSSPAARPKESLSSPQSDVFPAMEIFPPPPPPVQWEEEQSQSTSAKSLPQNEEIDAALPEAPKIPPSSFLSRQKSLPTNPAPSLSLEKLRSFAAPKPYSPSSPSRFAQAVSSAVKRSQSLSHHAPVQETRTHTLTKQRPIRESPEPPTSTVADNGDREPETQTADTDPVMGTCKIGNTQASPGSEASSQEVSDVFHSAEE", "length": 1070, "header": "tr|A0AB32U116-1|A0A8M6Z2T6_DANRE Computationally mapped isoform of Cordon-bleu protein-like 1b OS=Danio rerio OX=7955 GN=cobll1b PE=4 SV=1 CANONICAL=A0A8M6Z2T6-1" }, "locus": {} }, { "isoform_ac": "A0AC58GD15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6/entry#A0AC58GD15-1", "sequence": { "sequence": "MTGVDLYLQDRRSTKSKAPPPPVLTGLDAPLLSHKLQAFPHPAMEQTESLLEQELTLTVILPGGAEKITTVHGSKPMMDLLVMLCAQHHLNPSGHTLELITTNRNHVKFKPNALIGALEADKILLKPKGMEDKSKKTGPHMPEATVRLVINYRKTQKTILRVSPRVPLRELLPAICQKCEFDPQTTLLSPSVQSEDTLDLSGSLNDFGLREVYARDTRVISPVSPISPVSLPPSPTRSEIFYHGKEKSLREKDNKRRFSLFRRGSKKQSEQSMTVSAPASPVHRKQRPVSMSSFSTHVPLSYDCNTMPSDTPKKRRAPLPPSMMSQSMPSDLSQTQTTVHPDGNQNLSSLSRASSTESSFKKSSTKRKAPPPPVMISTDTTHQDTTDSSMTESAVTSPLEEIKEQEEMSVGAGVNVEDETLEDNSSLNMSANISLDSGRAGTATPSQDSVTLESGTPRDDPVCDLSTDAEVAEGTVNGEMKADQTRSSHITSEDKDPGKTEQLIQPSESGPVLEEVTVSNTSLPQRSECGIQTSQTDLQVQCFDSDTAISSPESSCSIYAEAQTSKTIPNTSSLTHTETQTQVQSSNEPSSLCTEFSTSTIGLKKDMATSTDELQPSIQQSKDLTSTSKPASVSYVTDAEPKPKPSNEHTRGYIPKVGMTTYTIVPQKSLEKLHSLEIEMTLEPKVDCKPNVSNGTVTLNGHQNAFAQTNQCTSPPATNSTNLSTNLSTKPTSLSANTTYSSTKPTSSSTSPTYLSTNPTNWSTNPINSSTSPTYLSTNPSNSSTNPTNSSTKQTNSSTNPTNSSSVDERIDSVSLKDKKVPPATRPKPASFRVPQHKRMSGDYVSSAAVRRASIGSSSSSSSCCSSPAARPKESLSSPQSDVFPAMEIFPPPPPPVQWEEEQSQSTSAKSLPQNEEIDAALPEAPKIPPSSFLSRQKSLPTNPAPSLSLEKLRSFAAPKPYSPSSPSRFAQAVSSAVKRSQSLSHHAPVQETRTHTLTKQRPIRESPEPPTSTGSEASSQEVSDVFHSAEE", "length": 1032, "header": "tr|A0AC58GD15-1|A0AC58GD15_DANRE Computationally mapped isoform of Cordon-bleu protein-like 1b isoform X8 OS=Danio rerio OX=7955 GN=cobll1b PE=4 SV=1 CANONICAL=A0A8M6Z2T6-1" }, "locus": {} }, { "isoform_ac": "A0AC58GD20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6/entry#A0AC58GD20-1", "sequence": { "sequence": "MYQISGIFRLFRGYLKRRSTKSKAPPPPVLTGLDAPLLSHKLQAFPHPAMEQTESLLEQELTLTVILPGGAEKITTVHGSKPMMDLLVMLCAQHHLNPSGHTLELITTNRNHVKFKPNALIGALEADKILLKPKGMEDKSKKTGPHMPEATVRLVINYRKTQKTILRVSPRVPLRELLPAICQKCEFDPQTTLLSPSVQSEDTLDLSGSLNDFGLREVYARDTRVISPVSPISPVSLPPSPTRSEIFYHGKEKSLREKDNKRRFSLFRRGSKKQSEQSMTVSAPASPVHRKQRPVSMSSFSTHVPLSYDCNTMPSDTPKKRRAPLPPSMMSQSMPSDLSQTQTTVHPDGNQNLSSLSRASSTESSFKKSSTKRKAPPPPVMISTDTTHQDTTDSSMTESAVTSPLEEIKEQEEMSVGAGVNVEDETLEDNSSLNMSANISLDSGRAGTATPSQDSVTLESGTPRDDPVCDLSTDAEVAEGTVNGEMKADQTRSSHITSEDKDPGKTEQLIQPSESGPVLEEVTVSNTSLPQRSECGIQTSQTDLQVQCFDSDTAISSPESSCSIYAEAQTSKTIPNTSSLTHTETQTQVQSSNEPSSLCTEFSTSTIGLKKDMATSTDELQPSIQQSKDLTSTSKPASVSYVTDAEPKPKPSNEHTRGYIPKVGMTTYTIVPQKSLEKLHSLEIEMTLEPKVDCKPNVSNGTVTLNGHQNAFAQTNQCTSPPATNSTNLSTNLSTKPTSLSANTTYSSTKPTSSSTSPTYLSTNPTNWSTNPINSSTSPTYLSTNPSNSSTNPTNSSTKQTNSSTNPTNSSSVDERIDSVSLKDKKVPPATRPKPASFRVPQHKRMSGDYVSSAAVRRASIGSSSSSSSCCSSPAARPKESLSSPQSDVFPAMEIFPPPPPPVQWEEEQSQSTSAKSLPQNEEIDAALPEAPKIPPSSFLSRQKSLPTNPAPSLSLEKLRSFAAPKPYSPSSPSRFAQAVSSAVKRSQSLSHHAPVQETRTHTLTKQRPIRESPEPPTSTGSEASSQEVSDVFHSAEE", "length": 1038, "header": "tr|A0AC58GD20-1|A0AC58GD20_DANRE Computationally mapped isoform of Cordon-bleu protein-like 1b isoform X7 OS=Danio rerio OX=7955 GN=cobll1b PE=4 SV=1 CANONICAL=A0A8M6Z2T6-1" }, "locus": {} }, { "isoform_ac": "A0AC58GD24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6/entry#A0AC58GD24-1", "sequence": { "sequence": "MYQISGIFRLFRGYLKRRSTKSKAPPPPVLTGLDAPLLSHKLQAFPHPAMEQTESLLEQELTLTVILPGGAEKITTVHGSKPMMDLLVMLCAQHHLNPSGHTLELITTNRNHVKFKPNALIGALEADKILLKPKGMEDKSKKTGPHMPEATVRLVINYRKTQKTILRVSPRVPLRELLPAICQKCEFDPQTTLLSPSVQSEDTLDLSGSLNDFGLREVYARDTRVISPVSPISPVSLPPSPTRSEIFYHGKEKSLREKDNKRRFSLFRRGSKKQSEQSMTVSAPASPVHRKQRPVSMSSFSTHVPLSYDCNTMPSDTPKKRRAPLPPSMMSQSMPSDLSQTQTTVHPDGNQNLSSLSRASSTESSFKKSSTKRKAPPPPVMISTDTTHQDTTDSSMTESAVTSPLEEIKEQEEMSVGAGVNVEDETLEDNSSLNMSANISLDSGRAGTATPSQDSVTLESGTPRDDPVCDLSTDAEVAEGTVNGEMKADQTRSSHITSEDKDPGKTEQLIQPSESGPVLEEVTVSNTSLPQRSECGIQTSQTDLQVQCFDSDTAISSPESSCSIYAEAQTSKTIPNTSSLTHTETQTQVQSSNEPSSLCTEFSTSTIGLKKDMATSTDELQPSIQQSKDLTSTSKPASVSYVTDAEPKPKPSNEHTRGYIPKVGMTTYTIVPQKSLEKLHSLEIEMTLEPKVDCKPNVSNGTVTLNGHQNAFAQTNQCTSPPATNSTNLSTNLSTKPTSLSANTTYSSTKPTSSSTSPTYLSTNPTNWSTNPINSSTSPTYLSTNPSNSSTNPTNSSTKQTNSSTNPTNSSSVDERIDSVSLKDKKVPPATRPKPASFRVPQHKRMSGDYVSSAAVRRASIGSSSSSSSCCSSPAARPKESLSSPQSDVFPAMEIFPPPPPPVQWEEEQSQSTSAKSLPQNEEIDAALPEAPKIPPSSFLSRQKSLPTNPAPSLSLEKLRSFAAPKPYSPSSPSRFAQAVSSAVKRSQSLSHHAPVQETRTHTLTKQRPIRESPEPPTSTVADNGDREPETQTADTDPVMGTWV", "length": 1044, "header": "tr|A0AC58GD24-1|A0AC58GD24_DANRE Computationally mapped isoform of Cordon-bleu protein-like 1b isoform X6 OS=Danio rerio OX=7955 GN=cobll1b PE=4 SV=1 CANONICAL=A0A8M6Z2T6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 469, "start_aa": "Thr", "end_pos": 469, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr469", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Cobll1 is linked to drug resistance and blastic transformation in chronic myeloid leukemia.", "journal": "Leukemia", "date": "2017", "authors": "Han SH, Kim SH, Kim HJ, Lee Y, Choi SY, Park G, Kim DH, Lee A, Kim J, Choi JM, Kim Y, Myung K, Kim H, Kim DW", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6" } ], "reference": [ { "type": "PubMed", "id": "28232743", "url": "https://glygen.org/publication/PubMed/28232743" } ] }, { "title": "A comparative study of the expression patterns of Fign family members in zebrafish embryonic development.", "journal": "Comp. Biochem. Physiol.", "date": "2021", "authors": "Dong Zhangji, Li Yuanyuan, Chen Xu, Lai Xiaona, Liu Mei", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6" } ], "reference": [ { "type": "PubMed", "id": "33069857", "url": "https://glygen.org/publication/PubMed/33069857" } ] }, { "title": "Genome-wide analysis of copy-number variation in humans with cleft lip and/or cleft palate identifies COBLL1, RIC1, and ARHGEF38 as clefting genes.", "journal": "Am. J. Hum. Genet.", "date": "2023", "authors": "Lansdon Lisa A, Dickinson Amanda, Arlis Sydney, Liu Huan, Hlas Arman, Hahn Alyssa, Bonde Greg, Long Abby, Standley Jennifer, Tyryshkina Anastasia, Wehby George, Lee Nanette R, Daack-Hirsch Sandra, Mohlke Karen, Girirajan Santhosh, Darbro Benjamin W, Cornell Robert A, Houston Douglas W, Murray Jeffrey C, Manak J Robert", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6" } ], "reference": [ { "type": "PubMed", "id": "36493769", "url": "https://glygen.org/publication/PubMed/36493769" } ] } ], "pathway": [ { "id": "dre:100332245", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100332245", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LX00-1", "protein_name": "Cordon-bleu WH2 repeat protein-like 1", "gene_name": "Cobll1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTEYNCCKVSLASSACLLLRFLWSLTFAYCTVLYLGTNKPSPGEHIELSEGKLSVSTAGAKHTSFLHEVPNHRRKTKAKAPLPPAEMKGMDVSSAEDPVESIPVSTEQHDNMIDKDIELSVVLPGDVLKSTTVHGSKPMMDLLVFLCAQYHLNPSSHTINLLSAEENLIKFKPNTPIGMLEVEKVILKPKSLDKKKPTPIIPEKTVRVVINFKKTQKTIVRVSPHSPLQDLAPIICSKCEFDPLHTVLLKDYQAQEPLDLTKSLNDLGLRELYAMDISRAPSVTAFSKSSFQESCQISHNPDIVKEKENKGIFSFFQRSKKKREQTASAPATPLVSKHRPSFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPTSQGAAQGQERRASCVERSTSVDDTDKSSSEGFMVRTGSLQLSGSTSVGTSSLKRTKRKAPAPPSKPSLTETDEGSSAAAHGLPLEDGIVPDSISEVSSPEGMSSPAGVSSDYSLEEIDEKEELMEASKDQAGSVKSPTIASASTDMIITAENDPDSALSISDGETSPGSKGNTPEGRNPEGQGPHHPVECLIGNENNVSDSIKDLKTLSPNQESVIQNEVVVCATSTDYVKNRPREMEATIEGEAQKKVGDVEAERLSGSPAGRMDDVQSSRENHLTASPGPDQKSNQPRVEKTKMQDAAIQATPACSTFDGNHEAHNSPDLRVDETAQTLGSSTSTQHSSASFQDSVNASREVRSQGTSTYVQDRLPVKEAACTYGNNDALSPIDGSGKNPAASSLKNFPLYRQDNHPKPKPSNEITREYIPKIGMTTYKIVPPKSLEVVKDWDSEAAGKKDNQKTLAVAQKHAIETMTETAVQAEALVTSKNSQQPQPDRTPKPSSGTEHPLHRTVSSPVGTEMNPPKPPRMTTDTGTIPFAPNLEDINNILESKFRSRASNPQAKPSSFFLQMQKRASGHYVTSAAAKSVHTAPGPTPKEPTIKEVQRDPQLPPEQCLSPLSERTHSAPLPNISKADDNRIQKPAETSPPPVAPKPMALPAETSPPAVAPKPMAFPAETSLPPVSPKPMALPTEASSSPISPKPMAPPAEASIPPVVPKPMAPPAEASPLPVAPKPMAFPAETSLPPVAPKPMALPTEASPPPVAPKPLALPGSQGASLNLKTLKTFGAPRPYNSSAPSPFALAVVKRSQSFSKASPESPSEDSSAQPPAAIQDGKTQTVNQPTVGSQHDGVDKQNKPVQNEHSSQRLTPADGPSSFTLQRQSSLNFQSSDPEHIRQSLLTAIRSGEAAAKLKRVTVPSNRISVNGKSGLSQPMSIDAQDSC", "length": 1310 }, "evidence": [ { "id": "HGNC:23571", "url": "https://alliancegenome.org/gene/HGNC:23571#orthology", "database": "AGR" }, { "id": "RGD:1308954", "url": "https://alliancegenome.org/gene/RGD:1308954#orthology", "database": "AGR" }, { "id": "MGI:2442894", "url": "https://alliancegenome.org/gene/MGI:2442894#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120313-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120313-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UMF0-1", "protein_name": "Cordon-bleu protein-like 1", "gene_name": "Cobll1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRSVPDPLPRSAPRTPAMQPAGSAGKRRFMKMFHAHSKNDFVRIKNHKFLPLHICQSRKTKGKAPLPPAETKGTDVSSAEDPVESTAVVTEQQDNMIDKDIELSVVLPGDILKSTTVHGSKPMMDLLVFLCAQYHLNPSSHTIDLLSAEENLIKFKPNTPIGMLDVEKVILKPKSLDKKKPTPIIPEKTVRVVINFKKTQKTIVRVSPHAPLQDLAPIICSKCEFDPLHTVLLKDYQAQEPLDLTKSLNDLGLRELYAMDISRESCQISHNPDIVKEKENKGIFSFFQRSKKKREQTASAPATPLVSKHRPSFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPTSQGAAQGQERRASCVERSTSVDDTDKSSSEAIMVRTGSLQLSSTSIGTSSLKRTKRKAPAPPSKTPLAQTDERNSAMAHGLPLEDGIAPDSMLELSSPEGMSTPEGSLGPGFLSQEQCAVPKPPDEISEGPGTPETAVASLTSGVSSDYSLEEIDEKEELSEASKDPAGSISVKSPDIASASTDMRITVEKDPDSALGISDGETSPSSKGKTQEGRSTEGQGPYHPVVGHIGNEDRVSDSIKDMKTLGPNQESVVQNEIMVCATSTDYVKNRPGKMETTIEGEGEALKKASDMETDRLSGSPACRMDNVKSSRENHLTASPGPDQKLNQPGVEKTKMQDAAIQATPARGTFDGNHEVSNSSDPRADETVQTSDGSISAQHSSASLQDSVNASREFRSQGTSTYVQDRLPEKEPACTYGNNVPLSPVDGSNKNPAASYLKNFPLYRQDSNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEMAKDWESEAMGRKDDQKMLPVGQRHTIENMTETSMQTEVPATSKSSQQPQPDLKPKPSSGTERHLHRTLSSPTGTETNPPKAPRVTTDTGTIPFAPNLEDINNILESKFRSRASNPQAKPSSFFLQMQKRASGHYVTSAAAKSVHTAPGPAPKEPTIKEVQRDPQLSPEQHPSSLSERTHSAPLPNISKADDDIIQKPAETSPPPVAPKPMTLRAETSPPPVFPKPMTLPAETSPPPVFPKPMTLPAETSLPLVFPKPMTLRAETSPPPVAAKPVALPGSQGTSLNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKACPESASEGSSALPPAATQDEKTHTVNKPTVGSQHGDGDKQNNPVQNEHSSQVLTPADGPSFTLKRQSSLTFQSSDPEHVRQSLLTAIRSGEAAAKLKRVTVPSNTISVNGKSGLSQSMSIDAQDSR", "length": 1273 }, "evidence": [ { "id": "HGNC:23571", "url": "https://alliancegenome.org/gene/HGNC:23571#orthology", "database": "AGR" }, { "id": "RGD:1308954", "url": "https://alliancegenome.org/gene/RGD:1308954#orthology", "database": "AGR" }, { "id": "MGI:2442894", "url": "https://alliancegenome.org/gene/MGI:2442894#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120313-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120313-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q53SF7-4", "protein_name": "Cordon-bleu protein-like 1", "gene_name": "COBLL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGRTPRPQDAPARRKPKAKAPLPPAETKYTDVSSAADSVESTAFIMEQKENMIDKDVELSVVLPGDIIKSTTVHGSKPMMDLLIFLCAQYHLNPSSYTIDLLSAEQNHIKFKPNTPIGMLEVEKVILKPKMLDKKKPTPIIPEKTVRVVINFKKTQKTIVRVSPHASLQELAPIICSKCEFDPLHTLLLKDYQSQEPLDLTKSLNDLGLRELYAMDVNRESCQISQNLDIMKEKENKGFFSFFQRSKKKRDQTASAPATPLVNKHRPTFTRSNTISKPYISNTLPSDAPKKRRAPLPPMPASQSVPQDLAHIQERPASCIVKSMSVDETDKSPCEAGRVRAGSLQLSSMSAGNSSLRRTKRKAPSPPSKIPPHQSDENSRVTALQPVDGVPPDSASEANSPEELSSPAGISSDYSLEEIDEKEELSEVPKVEAENISPKSQDIPFVSTDIINTLKNDPDSALGNGSGEFSQNSMEEKQETKSTDGQEPHSVVYDTSNGKKVVDSIRNLKSLGPNQENVVQNEIIVYPENTEDNMKNGVKKTEINVEGVAKNNNIDMEVERPSNSEAHETDTAISYKENHLAASSVPDQKLNQPSAEKTKDAAIQTTPSCNSFDGKHQDHNLSDSKVEECVQTSNNNISTQHSCLSSQDSVNTSREFRSQGTLIIHSEDPLTVKDPICAHGNDDLLPPVDRIDKNSTASYLKNYPLYRQDYNPKPKPSNEITREYIPKIGMTTYKIVPPKSLEISKDWQSETIEYKDDQDMHALGKKHTHENVKETAIQTEDSAISESPEEPLPNLKPKPNLRTEHQVPSSVSSPDDAMVSPLKPAPKMTRDTGTAPFAPNLEEINNILESKFKSRASNAQAKPSSFFLQMQKRVSGHYVTSAAAKSVHAAPNPAPKELTNKEAERDMLPSPEQTLSPLSKMPHSVPQPLVEKTDDDVIGQAPAEASPPPIAPKPVTIPASQVSTQNLKTLKTFGAPRPYSSSGPSPFALAVVKRSQSFSKERTESPSASALVQPPANTEEGKTHSVNKFVDIPQLGVSDKENNSAHNEQNSQIPTPTDGPSFTVMRQSSLTFQSSDPEQMRQSLLTAIRSGEAAAKLKRVTIPSNTISVNGRSRLSHSMSPDAQDGH", "length": 1128 }, "evidence": [ { "id": "HGNC:23571", "url": "https://alliancegenome.org/gene/HGNC:23571#orthology", "database": "AGR" }, { "id": "RGD:1308954", "url": "https://alliancegenome.org/gene/RGD:1308954#orthology", "database": "AGR" }, { "id": "MGI:2442894", "url": "https://alliancegenome.org/gene/MGI:2442894#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120313-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120313-6#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin monomer binding", "id": "GO:0003785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003785", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "hemopoiesis", "id": "GO:0030097", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030097", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 371, "end_pos": 373, "annotation": "n_glycosylation_sequon" }, { "start_pos": 449, "end_pos": 451, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 595, "end_pos": 597, "annotation": "n_glycosylation_sequon" }, { "start_pos": 716, "end_pos": 718, "annotation": "n_glycosylation_sequon" }, { "start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 751, "end_pos": 753, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" }, { "start_pos": 786, "end_pos": 788, "annotation": "n_glycosylation_sequon" }, { "start_pos": 793, "end_pos": 795, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 814, "end_pos": 816, "annotation": "n_glycosylation_sequon" }, { "start_pos": 821, "end_pos": 823, "annotation": "n_glycosylation_sequon" }, { "start_pos": 828, "end_pos": 830, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z2T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T6" }, { "id": "PF09469", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09469" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cordon-bleu ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 243, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 469 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 371, "end_pos": 373 }, { "start_pos": 449, "end_pos": 451 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 457, "end_pos": 459 }, { "start_pos": 545, "end_pos": 547 }, { "start_pos": 595, "end_pos": 597 }, { "start_pos": 716, "end_pos": 718 }, { "start_pos": 719, "end_pos": 721 }, { "start_pos": 744, "end_pos": 746 }, { "start_pos": 747, "end_pos": 749 }, { "start_pos": 751, "end_pos": 753 }, { "start_pos": 762, "end_pos": 764 }, { "start_pos": 786, "end_pos": 788 }, { "start_pos": 793, "end_pos": 795 }, { "start_pos": 807, "end_pos": 809 }, { "start_pos": 814, "end_pos": 816 }, { "start_pos": 821, "end_pos": 823 }, { "start_pos": 828, "end_pos": 830 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9P1G9-1", "uniprot_ac": "A0A8M9P1G9", "uniprot_id": "A0A8M9P1G9_DANRE", "mass": { "chemical_mass": 99910.0, "monoisotopic_mass": 99910.0 }, "refseq": { "ac": "XP_021323547", "name": "rho GTPase-activating protein 42-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323547" }, "gene_names": [ { "name": "arhgap42b", "type": "recommended", "evidence": [ { "id": "A0A8M9P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9" } ] }, { "name": "arhgap42b", "type": "synonym", "evidence": [ { "id": "XP_021323547", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323547" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 42", "type": "recommended", "evidence": [ { "id": "A0A8M9P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#names_and_taxonomy" } ] }, { "name": "Rho GTPase-activating protein 10-like", "type": "synonym", "evidence": [ { "id": "A0A8M9P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#names_and_taxonomy" } ] }, { "name": "Rho-type GTPase-activating protein 42", "type": "synonym", "evidence": [ { "id": "A0A8M9P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 42-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323547", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323547" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323547.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323547", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323547" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P1G9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "arhgap42b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120217-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120217-5", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P1G9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P1G9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01249", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01249", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04374", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04374", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "569534", "url": "https://www.ncbi.nlm.nih.gov/gene/569534", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004148", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004148", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569534", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569534", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YTR2", "url": "https://www.orthodb.org/?gene=A0A8M6YTR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z271", "url": "https://www.orthodb.org/?gene=A0A8M6Z271", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P1G9", "url": "https://www.orthodb.org/?gene=A0A8M9P1G9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12552", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12552", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12552:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12552:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16746", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16746", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323547", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323547", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YTR2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YTR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YTR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YTR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z271", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z271", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z271-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z271-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P1G9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P1G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PAJ8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PAJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HVZ4", "url": "https://www.uniprot.org/uniprotkb/A0AC58HVZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HVZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HVZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HVZ6", "url": "https://www.uniprot.org/uniprotkb/A0AC58HVZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HVZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HVZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW05", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW05-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW07", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW07-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW09", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW09-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW11", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW11-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120217-5", "url": "https://zfin.org/ZDB-GENE-120217-5", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGLPTLEFSDSFVDSPDFRERLKCHEIELDRTNKFIKELIKDGHQLICALKNLSAAVQKFSQSLQEFQFECIGDAETDDEVNIAQSFKEFSKLLHTMEEERRRLIQNADDVLITPLERFRKEQIGAAKEGKKKFDKEAEKYYSTLDKHLNLSSRKKESALQEADAQIDRERQLFYDASLEYVFKIQDVQEKKKFEFVEPLLAFLQGLFTFYHEGYELAHDFEPYKQQLQFNLQNTRNNFLSTKQEVENLMNRVRSADQDQKPPGQWTMEGYLYVQEKRPLGCTWTRHYCTYDKDNQTFSMCNTEAKPAAKQNGVTSNPPEKFRLKSCIRRKTDSIDKRFCFDIEVVERNTVYRGSLFRPLQFFFKSRHGIITLQALSESNRRLWLEAMDGKEPIYNLPAILSKKEETYLNETGFNFVRKCIQLVEVRAGLNTMGLYRVGGINSKVQKLMTTVFSPKAASDLDLDPDTWDNKTITSGLKNYLRCLSEPLMTYKLHSDFLMAVKSDDQNYRVCAVHALVHKLPDKNREMLEILIKHLLNVSSHSESNMMTVSNLGVIFGPTLMRSQEETVAAMMNIKFQNIVVEILIENLEKIFHQAPDPNVPLLQPLSRPESRRSRAIGLTSGPRKPRSLYTPSLCLADADSDTFSSSSGSTPIGSMDSLSSHSSEQNSSSKTCSSPQHKDKPPFPGPRSPFSRSSSEPQGPAGTSSPDSSSREQDCPADESFRGNLRSTTAPTKAPHAQLNRSIAQSLRSLHLTEGVCKSFAGSVHSLACVDGSKSTTCLDLPPKALLRRKLDNNSSTNGYQRPGSVVAARALLFENPSAVKHPPVGRDAKAIYSCEAEHSNELSFPQGAHFSNVYPSVEPGWLQATFEGKTGLIPENYVVFL", "length": 883, "header": "tr|A0A8M9P1G9-1|A0A8M9P1G9_DANRE Isoform 1 of Rho GTPase-activating protein 42 OS=Danio rerio OX=7955 GN=arhgap42b PE=4 SV=2 CANONICAL=A0A8M9P1G9-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YTR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#A0A8M6YTR2-1", "sequence": { "sequence": "MGLPTLEFSDSFVDSPDFRERLKCHEIELDRTNKFIKELIKDGHQLICALKNLSAAVQKFSQSLQEFQFECIGDAETDDEVNIAQSFKEFSKLLHTMEEERRRLIQNADDVLITPLERFRKEQIGAAKEGKKKFDKEAEKYYSTLDKHLNLSSRKKESALQEADAQIDRERQLFYDASLEYVFKIQDVQEKKKFEFVEPLLAFLQGLFTFYHEGYELAHDFEPYKQQLQFNLQNTRNNFLSTKQEVENLMNRVRSADQDQKPPGQWTMEGYLYVQEKRPLGCTWTRHYCTYDKDNQTFSMCNTEAKPAAKQNGVTSNPPEKFRLKSCIRRKTDSIDKRFCFDIEVVERNTVYRGSLFRPLQFFFKSRHGIITLQALSESNRRLWLEAMDGKEPIYNLPAILSKKEETYLNETGFNFVRKCIQLVEVRGLNTMGLYRVGGINSKVQKLMTTVFSPKAASDLDLDPDTWDNKTITSGLKNYLRCLSEPLMTYKLHSDFLMAVKSDDQNYRVCAVHALVHKLPDKNREMLEILIKHLLNVSSHSESNMMTVSNLGVIFGPTLMRSQEETVAAMMNIKFQNIVVEILIENLEKIFHQAPDPNVPLLQPLSRPESRRSRAIGLTSGPRKPRSLYTPSLCLADADSDTFSSSSGSTPIGSMDSLSSHSSEQNSSSKTCSSPQHKDKPPFPGPRSPFSRSSSEPQGPAGTSSPDSSSREQDCPADESFRGNLRSTTAPTKAPHAQLNRSIAQSLRSLHLTEGVCKSFAGSVHSLACVDGSKSTTCLDLPPKALLRRKLDNNSSTNGYQRPGSVVAARALLFENPSAVKHPPVGRDAKAIYSCEAEHSNELSFPQGAHFSNVYPSVEPGWLQATFEGKTGLIPENYVVFL", "length": 882, "header": "tr|A0A8M6YTR2-1|A0A8M9P1G9_DANRE Computationally mapped isoform of Rho GTPase-activating protein 42 OS=Danio rerio OX=7955 GN=arhgap42b PE=4 SV=2 CANONICAL=A0A8M9P1G9-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z271-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#A0A8M6Z271-1", "sequence": { "sequence": "MGLPTLEFSDSFVDSPDFRERLKCHEIELDRTNKFIKELIKDGHQLICALKNLSAAVQKFSQSLQEFQFECIGDAETDDEVNIAQSFKEFSKLLHTMEEERRRLIQNADDVLITPLERFRKEQIGAAKEGKKKFDKEAEKYYSTLDKHLNLSSRKKESALQEADAQIDRERQLFYDASLEYVFKIQDVQEKKKFEFVEPLLAFLQGLFTFYHEGYELAHDFEPYKQQLQFNLQNTRNNFLSTKQEVENLMNRVRSADQDQKPPGQWTMEGYLYVQEKRPLGCTWTRHYCTYDKDNQTFSMCNTEAKPAAKQNGVTSNPPEKFRLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQALSESNRRLWLEAMDGKEPIYNLPAILSKKEETYLNETGFNFVRKCIQLVEVRGLNTMGLYRVGGINSKVQKLMTTVFSPKAASDLDLDPDTWDNKTITSGLKNYLRCLSEPLMTYKLHSDFLMAVKSDDQNYRVCAVHALVHKLPDKNREMLEILIKHLLNVSSHSESNMMTVSNLGVIFGPTLMRSQEETVAAMMNIKFQNIVVEILIENLEKIFHQAPDPNVPLLQPLSRPESRRSRAIGLTSGPRKPRSLYTPSLCLADADSDTFSSSSGSTPIGSMDSLSSHSSEQNSSSKTCSSPQHKDKPPFPGPRSPFSRSSSEPQGPAGTSSPDSSSREQDCPADESFRGNLRSTTAPTKAPHAQLNRSIAQSLRSLHLTEGVCKSFAGSVHSLACVDGSKSTTCLDLPPKALLRRKLDNNSSTNGYQRPGSVVAARALLFENPSAVKHPPVGRDAKAIYSCEAEHSNELSFPQGAHFSNVYPSVEPGWLQATFEGKTGLIPENYVVFL", "length": 863, "header": "tr|A0A8M6Z271-1|A0A8M9P1G9_DANRE Computationally mapped isoform of Rho GTPase-activating protein 42 OS=Danio rerio OX=7955 GN=arhgap42b PE=4 SV=2 CANONICAL=A0A8M9P1G9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P1G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#A0A8M9P1G9-1", "sequence": { "sequence": "MGLPTLEFSDSFVDSPDFRERLKCHEIELDRTNKFIKELIKDGHQLICALKNLSAAVQKFSQSLQEFQFECIGDAETDDEVNIAQSFKEFSKLLHTMEEERRRLIQNADDVLITPLERFRKEQIGAAKEGKKKFDKEAEKYYSTLDKHLNLSSRKKESALQEADAQIDRERQLFYDASLEYVFKIQDVQEKKKFEFVEPLLAFLQGLFTFYHEGYELAHDFEPYKQQLQFNLQNTRNNFLSTKQEVENLMNRVRSADQDQKPPGQWTMEGYLYVQEKRPLGCTWTRHYCTYDKDNQTFSMCNTEAKPAAKQNGVTSNPPEKFRLKSCIRRKTDSIDKRFCFDIEVVERNTVYRGSLFRPLQFFFKSRHGIITLQALSESNRRLWLEAMDGKEPIYNLPAILSKKEETYLNETGFNFVRKCIQLVEVRAGLNTMGLYRVGGINSKVQKLMTTVFSPKAASDLDLDPDTWDNKTITSGLKNYLRCLSEPLMTYKLHSDFLMAVKSDDQNYRVCAVHALVHKLPDKNREMLEILIKHLLNVSSHSESNMMTVSNLGVIFGPTLMRSQEETVAAMMNIKFQNIVVEILIENLEKIFHQAPDPNVPLLQPLSRPESRRSRAIGLTSGPRKPRSLYTPSLCLADADSDTFSSSSGSTPIGSMDSLSSHSSEQNSSSKTCSSPQHKDKPPFPGPRSPFSRSSSEPQGPAGTSSPDSSSREQDCPADESFRGNLRSTTAPTKAPHAQLNRSIAQSLRSLHLTEGVCKSFAGSVHSLACVDGSKSTTCLDLPPKALLRRKLDNNSSTNGYQRPGSVVAARALLFENPSAVKHPPVGRDAKAIYSCEAEHSNELSFPQGAHFSNVYPSVEPGWLQATFEGKTGLIPENYVVFL", "length": 883, "header": "tr|A0A8M9P1G9-1|A0A8M9P1G9_DANRE Isoform 1 of Rho GTPase-activating protein 42 OS=Danio rerio OX=7955 GN=arhgap42b PE=4 SV=2 CANONICAL=A0A8M9P1G9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PAJ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#A0A8M9PAJ8-1", "sequence": { "sequence": "MGLPTLEFSDSFVDSPDFRERLKCHEIELDRTNKFIKELIKDGHQLICALKNLSAAVQKFSQSLQEFQFECIGDAETDDEVNIAQSFKEFSKLLHTMEEERRRLIQNADDVLITPLERFRKEQIGAAKEGKKKFDKEAEKYYSTLDKHLNLSSRKKESALQEADAQIDRERQLFYDASLEYVFKIQDVQEKKKFEFVEPLLAFLQGLFTFYHEGYELAHDFEPYKQQLQFNLQNTRNNFLSTKQEVENLMNRVRSADQDQKPPGQWTMEGYLYVQEKRPLGCTWTRHYCTYDKDNQTFSMCNTEAKPAAKQNGVTSNPPEKFRLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQALSESNRRLWLEAMDGKEPIYNLPAILSKKEETYLNETGFNFVRKCIQLVEVRAGLNTMGLYRVGGINSKVQKLMTTVFSPKAASDLDLDPDTWDNKTITSGLKNYLRCLSEPLMTYKLHSDFLMAVKSDDQNYRVCAVHALVHKLPDKNREMLEILIKHLLNVSSHSESNMMTVSNLGVIFGPTLMRSQEETVAAMMNIKFQNIVVEILIENLEKIFHQAPDPNVPLLQPLSRPESRRSRAIGLTSGPRKPRSLYTPSLCLADADSDTFSSSSGSTPIGSMDSLSSHSSEQNSSSKTCSSPQHKDKPPFPGPRSPFSRSSSEPQGPAGTSSPDSSSREQDCPADESFRGNLRSTTAPTKAPHAQLNRSIAQSLRSLHLTEGVCKSFAGSVHSLACVDGSKSTTCLDLPPKALLRRKLDNNSSTNGYQRPGSVVAARALLFENPSAVKHPPVGRDAKAIYSCEAEHSNELSFPQGAHFSNVYPSVEPGWLQATFEGKTGLIPENYVVFL", "length": 864, "header": "tr|A0A8M9PAJ8-1|A0A8M9PAJ8_DANRE Computationally mapped isoform of Rho GTPase-activating protein 42 OS=Danio rerio OX=7955 GN=arhgap42b PE=4 SV=2 CANONICAL=A0A8M9P1G9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HVZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#A0AC58HVZ4-1", "sequence": { "sequence": "MMIRVYHLVFKFIYFNLISDLPLILPCSLFHFPSCCGENKTSTWPLGCTWTRHYCTYDKDNQTFSMCNTEAKPAAKQNGVTSNPPEKFRLKSCIRRKTDSIDKRFCFDIEVVERNTVYRGSLFRPLQFFFKSRHGIITLQALSESNRRLWLEAMDGKEPIYNLPAILSKKEETYLNETGFNFVRKCIQLVEVRAGLNTMGLYRVGGINSKVQKLMTTVFSPKAASDLDLDPDTWDNKTITSGLKNYLRCLSEPLMTYKLHSDFLMAVKSDDQNYRVCAVHALVHKLPDKNREMLEILIKHLLNVSSHSESNMMTVSNLGVIFGPTLMRSQEETVAAMMNIKFQNIVVEILIENLEKIFHQAPDPNVPLLQPLSRPESRRSRAIGLTSGPRKPRSLYTPSLCLADADSDTFSSSSGSTPIGSMDSLSSHSSEQNSSSKTCSSPQHKDKPPFPGPRSPFSRSSSEPQGPAGTSSPDSSSREQDCPADESFRGNLRSTTAPTKAPHAQLNRSIAQSLRSLHLTEGVCKSFAGSVHSLACVDGSKSTTCLDLPPKALLRRKLDNNSSTNGYQRPGSVVAARALLFENPSAVKHPPVGRDAKAIYSCEAEHSNELSFPQGAHFSNVYPSVEPGWLQATFEGKTGLIPENYVVFL", "length": 649, "header": "tr|A0AC58HVZ4-1|A0AC58HVZ4_DANRE Computationally mapped isoform of Rho GTPase-activating protein 42 isoform X9 OS=Danio rerio OX=7955 GN=arhgap42b PE=4 SV=1 CANONICAL=A0A8M9P1G9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HVZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#A0AC58HVZ6-1", "sequence": { "sequence": "MMIRVYHLVFKFIYFNLISDLPLILPCSLFHFPSCCGENKTSTWPLGCTWTRHYCTYDKDNQTFSMCNTEAKPAAKQNGVTSNPPEKFRLKSCIRRKTDSIDKRFCFDIEVVERNTVYRGSLFRPLQFFFKSRHGIITLQALSESNRRLWLEAMDGKEPIYNLPAILSKKEETYLNETGFNFVRKCIQLVEVRGLNTMGLYRVGGINSKVQKLMTTVFSPKAASDLDLDPDTWDNKTITSGLKNYLRCLSEPLMTYKLHSDFLMAVKSDDQNYRVCAVHALVHKLPDKNREMLEILIKHLLNVSSHSESNMMTVSNLGVIFGPTLMRSQEETVAAMMNIKFQNIVVEILIENLEKIFHQAPDPNVPLLQPLSRPESRRSRAIGLTSGPRKPRSLYTPSLCLADADSDTFSSSSGSTPIGSMDSLSSHSSEQNSSSKTCSSPQHKDKPPFPGPRSPFSRSSSEPQGPAGTSSPDSSSREQDCPADESFRGNLRSTTAPTKAPHAQLNRSIAQSLRSLHLTEGVCKSFAGSVHSLACVDGSKSTTCLDLPPKALLRRKLDNNSSTNGYQRPGSVVAARALLFENPSAVKHPPVGRDAKAIYSCEAEHSNELSFPQGAHFSNVYPSVEPGWLQATFEGKTGLIPENYVVFL", "length": 648, "header": "tr|A0AC58HVZ6-1|A0AC58HVZ6_DANRE Computationally mapped isoform of Rho GTPase-activating protein 42 isoform X10 OS=Danio rerio OX=7955 GN=arhgap42b PE=4 SV=1 CANONICAL=A0A8M9P1G9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HW05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#A0AC58HW05-1", "sequence": { "sequence": "MGLPTLEFSDSFVDSPDFRERLKCHEIELDRTNKFIKELIKDGHQLICALKNLSAAVQKFSQSLQEFQFECIGDAETDDEVNIAQSFKEFSKLLHTMEEERRRLIQNADDVLITPLERFRKEQIGAAKEGKKKFDKEAEKYYSTLDKHLNLSSRKKESALQEADAQIDRERQLFYDASLEYVFKIQDVQEKKKFEFVEPGLFTFYHEGYELAHDFEPYKQQLQFNLQNTRNNFLSTKQEVENLMNRVRSADQDQKPPGQWTMEGYLYVQEKRPLGCTWTRHYCTYDKDNQTFSMCNTEAKPAAKQNGVTSNPPEKFRLKSCIRRKTDSIDKRFCFDIEVVERNTVYRGSLFRPLQFFFKSRHGIITLQALSESNRRLWLEAMDGKEPIYNLPAILSKKEETYLNETGFNFVRKCIQLVEVRAGLNTMGLYRVGGINSKVQKLMTTVFSPKAASDLDLDPDTWDNKTITSGLKNYLRCLSEPLMTYKLHSDFLMAVKSDDQNYRVCAVHALVHKLPDKNREMLEILIKHLLNVSSHSESNMMTVSNLGVIFGPTLMRSQEETVAAMMNIKFQNIVVEILIENLEKIFHQAPDPNVPLLQPLSRPESRRSRAIGLTSGPRKPRSLYTPSLCLADADSDTFSSSSGSTPIGSMDSLSSHSSEQNSSSKTCSSPQHKDKPPFPGPRSPFSRSSSEPQGPAGTSSPDSSSREQDCPADESFRGNLRSTTAPTKAPHAQLNRSIAQSLRSLHLTEGVCKSFAGSVHSLACVDGSKSTTCLDLPPKALLRRKLDNNSSTNGYQRPGSVVAARALLFENPSAVKHPPVGRDAKAIYSCEAEHSNELSFPQGAHFSNVYPSVEPGWLQATFEGKTGLIPENYVVFL", "length": 877, "header": "tr|A0AC58HW05-1|A0AC58HW05_DANRE Computationally mapped isoform of Rho GTPase-activating protein 42 OS=Danio rerio OX=7955 GN=arhgap42b PE=4 SV=1 CANONICAL=A0A8M9P1G9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HW07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#A0AC58HW07-1", "sequence": { "sequence": "MGLPTLEFSDSFVDSPDFRERLKCHEIELDRTNKFIKELIKDGHQLICALKNLSAAVQKFSQSLQEFQFECIGDAETDDEVNIAQSFKEFSKLLHTMEEERRRLIQNADDVLITPLERFRKEQIGAAKEGKKKFDKEAEKYYSTLDKHLNLSSRKKESALQEADAQIDRERQLFYDASLEYVFKIQDVQEKKKFEFVEPGLFTFYHEGYELAHDFEPYKQQLQFNLQNTRNNFLSTKQEVENLMNRVRSADQDQKPPGQWTMEGYLYVQEKRPLGCTWTRHYCTYDKDNQTFSMCNTEAKPAAKQNGVTSNPPEKFRLKSCIRRKTDSIDKRFCFDIEVVERNTVYRGSLFRPLQFFFKSRHGIITLQALSESNRRLWLEAMDGKEPIYNLPAILSKKEETYLNETGFNFVRKCIQLVEVRGLNTMGLYRVGGINSKVQKLMTTVFSPKAASDLDLDPDTWDNKTITSGLKNYLRCLSEPLMTYKLHSDFLMAVKSDDQNYRVCAVHALVHKLPDKNREMLEILIKHLLNVSSHSESNMMTVSNLGVIFGPTLMRSQEETVAAMMNIKFQNIVVEILIENLEKIFHQAPDPNVPLLQPLSRPESRRSRAIGLTSGPRKPRSLYTPSLCLADADSDTFSSSSGSTPIGSMDSLSSHSSEQNSSSKTCSSPQHKDKPPFPGPRSPFSRSSSEPQGPAGTSSPDSSSREQDCPADESFRGNLRSTTAPTKAPHAQLNRSIAQSLRSLHLTEGVCKSFAGSVHSLACVDGSKSTTCLDLPPKALLRRKLDNNSSTNGYQRPGSVVAARALLFENPSAVKHPPVGRDAKAIYSCEAEHSNELSFPQGAHFSNVYPSVEPGWLQATFEGKTGLIPENYVVFL", "length": 876, "header": "tr|A0AC58HW07-1|A0AC58HW07_DANRE Computationally mapped isoform of Rho GTPase-activating protein 42 OS=Danio rerio OX=7955 GN=arhgap42b PE=4 SV=1 CANONICAL=A0A8M9P1G9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HW09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#A0AC58HW09-1", "sequence": { "sequence": "MGLPTLEFSDSFVDSPDFRERLKCHEIELDRTNKFIKELIKDGHQLICALKNLSAAVQKFSQSLQEFQFECIGDAETDDEVNIAQSFKEFSKLLHTMEEERRRLIQNADDVLITPLERFRKEQIGAAKEGKKKFDKEAEKYYSTLDKHLNLSSRKKESALQEADAQIDRERQLFYDASLEYVFKIQDVQEKKKFEFVEPGLFTFYHEGYELAHDFEPYKQQLQFNLQNTRNNFLSTKQEVENLMNRVRSADQDQKPPGQWTMEGYLYVQEKRPLGCTWTRHYCTYDKDNQTFSMCNTEAKPAAKQNGVTSNPPEKFRLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQALSESNRRLWLEAMDGKEPIYNLPAILSKKEETYLNETGFNFVRKCIQLVEVRAGLNTMGLYRVGGINSKVQKLMTTVFSPKAASDLDLDPDTWDNKTITSGLKNYLRCLSEPLMTYKLHSDFLMAVKSDDQNYRVCAVHALVHKLPDKNREMLEILIKHLLNVSSHSESNMMTVSNLGVIFGPTLMRSQEETVAAMMNIKFQNIVVEILIENLEKIFHQAPDPNVPLLQPLSRPESRRSRAIGLTSGPRKPRSLYTPSLCLADADSDTFSSSSGSTPIGSMDSLSSHSSEQNSSSKTCSSPQHKDKPPFPGPRSPFSRSSSEPQGPAGTSSPDSSSREQDCPADESFRGNLRSTTAPTKAPHAQLNRSIAQSLRSLHLTEGVCKSFAGSVHSLACVDGSKSTTCLDLPPKALLRRKLDNNSSTNGYQRPGSVVAARALLFENPSAVKHPPVGRDAKAIYSCEAEHSNELSFPQGAHFSNVYPSVEPGWLQATFEGKTGLIPENYVVFL", "length": 858, "header": "tr|A0AC58HW09-1|A0AC58HW09_DANRE Computationally mapped isoform of Rho GTPase-activating protein 42 OS=Danio rerio OX=7955 GN=arhgap42b PE=4 SV=1 CANONICAL=A0A8M9P1G9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HW11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9/entry#A0AC58HW11-1", "sequence": { "sequence": "MGLPTLEFSDSFVDSPDFRERLKCHEIELDRTNKFIKELIKDGHQLICALKNLSAAVQKFSQSLQEFQFECIGDAETDDEVNIAQSFKEFSKLLHTMEEERRRLIQNADDVLITPLERFRKEQIGAAKEGKKKFDKEAEKYYSTLDKHLNLSSRKKESALQEADAQIDRERQLFYDASLEYVFKIQDVQEKKKFEFVEPGLFTFYHEGYELAHDFEPYKQQLQFNLQNTRNNFLSTKQEVENLMNRVRSADQDQKPPGQWTMEGYLYVQEKRPLGCTWTRHYCTYDKDNQTFSMCNTEAKPAAKQNGVTSNPPEKFRLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQALSESNRRLWLEAMDGKEPIYNLPAILSKKEETYLNETGFNFVRKCIQLVEVRGLNTMGLYRVGGINSKVQKLMTTVFSPKAASDLDLDPDTWDNKTITSGLKNYLRCLSEPLMTYKLHSDFLMAVKSDDQNYRVCAVHALVHKLPDKNREMLEILIKHLLNVSSHSESNMMTVSNLGVIFGPTLMRSQEETVAAMMNIKFQNIVVEILIENLEKIFHQAPDPNVPLLQPLSRPESRRSRAIGLTSGPRKPRSLYTPSLCLADADSDTFSSSSGSTPIGSMDSLSSHSSEQNSSSKTCSSPQHKDKPPFPGPRSPFSRSSSEPQGPAGTSSPDSSSREQDCPADESFRGNLRSTTAPTKAPHAQLNRSIAQSLRSLHLTEGVCKSFAGSVHSLACVDGSKSTTCLDLPPKALLRRKLDNNSSTNGYQRPGSVVAARALLFENPSAVKHPPVGRDAKAIYSCEAEHSNELSFPQGAHFSNVYPSVEPGWLQATFEGKTGLIPENYVVFL", "length": 857, "header": "tr|A0AC58HW11-1|A0AC58HW11_DANRE Computationally mapped isoform of Rho GTPase-activating protein 42 OS=Danio rerio OX=7955 GN=arhgap42b PE=4 SV=1 CANONICAL=A0A8M9P1G9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:569534", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569534", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P1G9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P1G9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P1G9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 410, "end_pos": 412, "annotation": "n_glycosylation_sequon" }, { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" }, { "start_pos": 537, "end_pos": 539, "annotation": "n_glycosylation_sequon" }, { "start_pos": 667, "end_pos": 669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 741, "end_pos": 743, "annotation": "n_glycosylation_sequon" }, { "start_pos": 794, "end_pos": 796, "annotation": "n_glycosylation_sequon" }, { "start_pos": 795, "end_pos": 797, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 265, "end_pos": 393, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 395, "end_pos": 592, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P1G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1G9" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 825, "end_pos": 883, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 410, "end_pos": 412 }, { "start_pos": 470, "end_pos": 472 }, { "start_pos": 52, "end_pos": 54 }, { "start_pos": 537, "end_pos": 539 }, { "start_pos": 667, "end_pos": 669 }, { "start_pos": 741, "end_pos": 743 }, { "start_pos": 794, "end_pos": 796 }, { "start_pos": 795, "end_pos": 797 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z376-1", "uniprot_ac": "A0A8M6Z376", "uniprot_id": "A0A8M6Z376_DANRE", "mass": { "chemical_mass": 88537.0, "monoisotopic_mass": 88537.0 }, "refseq": { "ac": "XP_017208471", "name": "bromodomain-containing protein 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208471" }, "gene_names": [ { "name": "brd8a", "type": "recommended", "evidence": [ { "id": "A0A8M6Z376", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376" } ] }, { "name": "brd8a", "type": "synonym", "evidence": [ { "id": "XP_017208471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208471" } ] } ], "protein_names": [ { "name": "Bromodomain-containing protein 8", "type": "recommended", "evidence": [ { "id": "A0A8M6Z376", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376/entry#names_and_taxonomy" } ] }, { "name": "bromodomain-containing protein 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017208471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208471" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017208471.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017208471", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208471" } ] } ], "disease": [ { "disease_id": "DOID:0050861", "recommended_name": { "id": "DOID:0050861", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050861", "name": "colorectal adenocarcinoma", "description": "A colorectal carcinoma that derives_from epithelial cells of glandular origin." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050861", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050861" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z376", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "brd8a", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091113-54", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-54", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z376", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z376", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05507", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05507", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100003763", "url": "https://www.ncbi.nlm.nih.gov/gene/100003763", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037966", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037966", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100003763", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003763", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YV99", "url": "https://www.orthodb.org/?gene=A0A8M6YV99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z376", "url": "https://www.orthodb.org/?gene=A0A8M6Z376", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z3W3", "url": "https://www.orthodb.org/?gene=A0A8M6Z3W3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15398", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15398", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15398:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15398:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017208471", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208471", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YV99", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YV99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YV99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YV99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z376", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z376-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3W3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3W3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ICX3", "url": "https://www.uniprot.org/uniprotkb/A0AC58ICX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ICX3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ICX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ICX8", "url": "https://www.uniprot.org/uniprotkb/A0AC58ICX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ICX8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ICX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ICY2", "url": "https://www.uniprot.org/uniprotkb/A0AC58ICY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ICY2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ICY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ICY5", "url": "https://www.uniprot.org/uniprotkb/A0AC58ICY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ICY5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ICY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091113-54", "url": "https://zfin.org/ZDB-GENE-091113-54", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASGVGKHKLLLGPTDPWSIREKLCLASSVMKSGDQNWVSVSRAIKPFAEPGRPPDWFSQKHCASQYSELLETTEAPKRKRGEKGEVVETVEDVIVRRLTAERIEELKRLIKDTQEKHRKLKRESELIQAGHLDSKLEELWEEIVRSRKQEEEEAEVKRKATDAAYQARQAVKNTPKRVPSVTVRSPSGACSPSLDFPIGDSSEDPGSTAAGPTVFVPLTELPGPGVVEASLGSLLDESTQKKLLGQKITPPPSPLLSELLKKGSLLPTSPRLAVEGETPSNQLAGSHENQMMTSSLPASQAATGAPTLSRLLEAGPAQFPSQLSSLATADSAPSAATSAVDVVAPLSTGEGAAGASVDNKEAVLGEEDLVTVSYMAEELDLETVGDIIAIIEEKGDENAEALDAAVVEAALSLCEDTGHSLTGSWEPNPFRPICPEPSSTSADLDPHSLNLLEGKREGPDACGSSSGCAQMYSTPSSTVPSVPQDPTPTVGLNSQPDTPRPEHTDQAQDEQPESLHSLIKSETEEWTRSQSDTRSDDDPVIKQHSKEVKEEEEEAGSDAEEGSVSEMKSGLEGDGAEDCGGEEDGDAVYLSEADGDTELDPPASESEDGYSMHTASSSIQLHTTADSIPSSPASSQFSICSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVHRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVFHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGREANRKQDPNDKDCVPMASPAFLLSLFDGGTRGRRCAIEADLKMKK", "length": 820, "header": "tr|A0A8M6Z376-1|A0A8M6Z376_DANRE Isoform 1 of Bromodomain-containing protein 8 OS=Danio rerio OX=7955 GN=brd8a PE=4 SV=2 CANONICAL=A0A8M6Z376-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YV99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376/entry#A0A8M6YV99-1", "sequence": { "sequence": "MASGVGKHKLLLGPTDPWSIREKLCLASSVMKSGDQNWVSVSRAIKPFAEPGRPPDWFSQKHCASQYSELLETTEAPKRKRGEKGEVVETVEDVIVRRLTAERIEELKRLIKDTQEKHRKLKRESELIQAGHLDSKLEELWEEIVRSRKQEEEEAEVKRKATDAAYQARQAVKNTPKRVPSVTVRSPSGACSPSLDFPIGDSSEDPGSTAAGPTVFVPLTELPGPGVVEASLGSLLDESTQKKLLGQKITPPPSPLLSELLKKGSLLPTSPRLAVEGETPSNQLAGSHENQMMTSSLPASQAATGAPTLSRLLEAGPAQFPSQLSSLATADSAPSAATSAVDVVAPLSTGEGAAGASVDNKEAVLGEEDLVTVSYMAEELDLETVGDIIAIIEEKGDENAEALDAAVVEAALSLCEDTGHSLTGSWEPNPFRPICPEPSSTSADLDPHSLNLLEGKREGPDACGSSSGCAQMYSTPSSTVPSVPQDPTPTVGLNSQPDTPRPEHTDQAQDEQPESLHSLIKSETEEWTRSQSDTRSDDDPVIKQHSKEVKEEEEEAGSDAEEGSVSEMKSGLEGDGAEDCGGEEDGDAVYLSEADGDTELDPPASESEDGYSMHTASSSIQLHTTADSIPSSPASSQFSICSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVHRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVFHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGREANRKQDPNDKDGGTRGRRCAIEADLKMKK", "length": 805, "header": "tr|A0A8M6YV99-1|A0A8M6Z376_DANRE Computationally mapped isoform of Bromodomain-containing protein 8 OS=Danio rerio OX=7955 GN=brd8a PE=4 SV=2 CANONICAL=A0A8M6Z376-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z376-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376/entry#A0A8M6Z376-1", "sequence": { "sequence": "MASGVGKHKLLLGPTDPWSIREKLCLASSVMKSGDQNWVSVSRAIKPFAEPGRPPDWFSQKHCASQYSELLETTEAPKRKRGEKGEVVETVEDVIVRRLTAERIEELKRLIKDTQEKHRKLKRESELIQAGHLDSKLEELWEEIVRSRKQEEEEAEVKRKATDAAYQARQAVKNTPKRVPSVTVRSPSGACSPSLDFPIGDSSEDPGSTAAGPTVFVPLTELPGPGVVEASLGSLLDESTQKKLLGQKITPPPSPLLSELLKKGSLLPTSPRLAVEGETPSNQLAGSHENQMMTSSLPASQAATGAPTLSRLLEAGPAQFPSQLSSLATADSAPSAATSAVDVVAPLSTGEGAAGASVDNKEAVLGEEDLVTVSYMAEELDLETVGDIIAIIEEKGDENAEALDAAVVEAALSLCEDTGHSLTGSWEPNPFRPICPEPSSTSADLDPHSLNLLEGKREGPDACGSSSGCAQMYSTPSSTVPSVPQDPTPTVGLNSQPDTPRPEHTDQAQDEQPESLHSLIKSETEEWTRSQSDTRSDDDPVIKQHSKEVKEEEEEAGSDAEEGSVSEMKSGLEGDGAEDCGGEEDGDAVYLSEADGDTELDPPASESEDGYSMHTASSSIQLHTTADSIPSSPASSQFSICSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVHRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVFHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGREANRKQDPNDKDCVPMASPAFLLSLFDGGTRGRRCAIEADLKMKK", "length": 820, "header": "tr|A0A8M6Z376-1|A0A8M6Z376_DANRE Isoform 1 of Bromodomain-containing protein 8 OS=Danio rerio OX=7955 GN=brd8a PE=4 SV=2 CANONICAL=A0A8M6Z376-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z3W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376/entry#A0A8M6Z3W3-1", "sequence": { "sequence": "MASGVGKHKLLLGPTDPWSIREKLCLASSVMKSGDQNWVSVSRAIKPFAEPGRPPDWFSQKHCASQYSELLETTEAPKRKRGEKGEVVETVEDVIVRRLTAERIEELKRLIKDTQEKHRKLKRESELIQAGHLDSKLEELWEEIVRSRKQEEEEAEVKRKATDAAYQARQAVKNTPKRVPSVTVRSPSGACSPSLDFPIGDSSEDPGSTAAGPTVFVPLTELPGPGVVEASLGSLLDESTQKKLLGQKITPPPSPLLSELLKKGSLLPTSPRLAVEGETPSNQLAGSHENQMMTSSLPASQAATGEGAAGASVDNKEAVLGEEDLVTVSYMAEELDLETVGDIIAIIEEKGDENAEALDAAVVEAALSLCEDTGHSLTGSWEPNPFRPICPEPSSTSADLDPHSLNLLEGKREGPDACGSSSGCAQMYSTPSSTVPSVPQDPTPTVGLNSQPDTPRPEHTDQAQDEQPESLHSLIKSETEEWTRSQSDTRSDDDPVIKQHSKEVKEEEEEAGSDAEEGSVSEMKSGLEGDGAEDCGGEEDGDAVYLSEADGDTELDPPASESEDGYSMHTASSSIQLHTTADSIPSSPASSQFSICSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVHRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVFHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGREANRKQDPNDKDCVPMASPAFLLSLFDGGTRGRRCAIEADLKMKK", "length": 775, "header": "tr|A0A8M6Z3W3-1|A0A8M6Z3W3_DANRE Computationally mapped isoform of Bromodomain-containing protein 8 OS=Danio rerio OX=7955 GN=brd8a PE=4 SV=2 CANONICAL=A0A8M6Z376-1" }, "locus": {} }, { "isoform_ac": "A0AC58ICX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376/entry#A0AC58ICX3-1", "sequence": { "sequence": "MMTSSLPASQAATGAPTLSRLLEAGPAQFPSQLSSLATADSAPSAATSAVDVVAPLSTGEGAAGASVDNKEAVLGEEDLVTVSYMAEELDLETVGDIIAIIEEKGDENAEALDAAVVEAALSLCEDTGHSLTGSWEPNPFRPICPEPSSTSADLDPHSLNLLEGKREGPDACGSSSGCAQMYSTPSSTVPSVPQDPTPTVGLNSQPDTPRPEHTDQAQDEQPESLHSLIKSETEEWTRSQSDTRSDDDPVIKQHSKEVKEEEEEAGSDAEEGSVSEMKSGLEGDGAEDCGGEEDGDAVYLSEADGDTELDPPASESEDGYSMHTASSSIQLHTTADSIPSSPASSQFSICSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVHRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVFHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGREANRKQDPNDKDCVPMASPAFLLSLFDGGTRGRRCAIEADLKMKK", "length": 529, "header": "tr|A0AC58ICX3-1|A0AC58ICX3_DANRE Computationally mapped isoform of Bromodomain-containing protein 8 OS=Danio rerio OX=7955 GN=brd8a PE=4 SV=1 CANONICAL=A0A8M6Z376-1" }, "locus": {} }, { "isoform_ac": "A0AC58ICX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376/entry#A0AC58ICX8-1", "sequence": { "sequence": "MASGVGKHKLLLGPTDPWSIREKLCLASSVMKSGDQNWVSVSRAIKPFAEPGRPPDWFSQKHCASQYSELLETTEAPKRKRGEKGEVVETVEDVIVRRLTAERIEELKRLIKDTQEKHRKLKRESELIQAGHLDSKLEELWEEIVRSRKQEEEEAEVKRKATDAAYQARQAVKNTPKRVPSVTVRSPSGACSPSLDFPIGDSSEDPGSTAAGPTVFVPLTELPGPGVVEASLGSLLDESTQKKLLGQKITPPPSPLLSELLKKGSLLPTSPRLAVEGETPSNQLAGSHENQMMTSSLPASQAATGEGAAGASVDNKEAVLGEEDLVTVSYMAEELDLETVGDIIAIIEEKGDENAEALDAAVVEAALSLCEDTGHSLTGSWEPNPFRPICPEPSSTSADLDPHSLNLLEGKREGPDACGSSSGCAQMYSTPSSTVPSVPQDPTPTVGLNSQPDTPRPEHTDQAQDEQPESLHSLIKSETEEWTRSQSDTRSDDDPVIKQHSKEVKEEEEEAGSDAEEGSVSEMKSGLEGDGAEDCGGEEDGDAVYLSEADGDTELDPPASESEDGYSMHTASSSIQLHTTADSIPSSPASSQFSICSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVHRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVFHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGREANRKQDPNDKDGGTRGRRCAIEADLKMKK", "length": 760, "header": "tr|A0AC58ICX8-1|A0AC58ICX8_DANRE Computationally mapped isoform of Bromodomain-containing protein 8 OS=Danio rerio OX=7955 GN=brd8a PE=4 SV=1 CANONICAL=A0A8M6Z376-1" }, "locus": {} }, { "isoform_ac": "A0AC58ICY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376/entry#A0AC58ICY2-1", "sequence": { "sequence": "MMTSSLPASQAATGEGAAGASVDNKEAVLGEEDLVTVSYMAEELDLETVGDIIAIIEEKGDENAEALDAAVVEAALSLCEDTGHSLTGSWEPNPFRPICPEPSSTSADLDPHSLNLLEGKREGPDACGSSSGCAQMYSTPSSTVPSVPQDPTPTVGLNSQPDTPRPEHTDQAQDEQPESLHSLIKSETEEWTRSQSDTRSDDDPVIKQHSKEVKEEEEEAGSDAEEGSVSEMKSGLEGDGAEDCGGEEDGDAVYLSEADGDTELDPPASESEDGYSMHTASSSIQLHTTADSIPSSPASSQFSICSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVHRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVFHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGREANRKQDPNDKDGGTRGRRCAIEADLKMKK", "length": 469, "header": "tr|A0AC58ICY2-1|A0AC58ICY2_DANRE Computationally mapped isoform of Bromodomain-containing protein 8 OS=Danio rerio OX=7955 GN=brd8a PE=4 SV=1 CANONICAL=A0A8M6Z376-1" }, "locus": {} }, { "isoform_ac": "A0AC58ICY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376/entry#A0AC58ICY5-1", "sequence": { "sequence": "MMTSSLPASQAATGAPTLSRLLEAGPAQFPSQLSSLATADSAPSAATSAVDVVAPLSTGEGAAGASVDNKEAVLGEEDLVTVSYMAEELDLETVGDIIAIIEEKGDENAEALDAAVVEAALSLCEDTGHSLTGSWEPNPFRPICPEPSSTSADLDPHSLNLLEGKREGPDACGSSSGCAQMYSTPSSTVPSVPQDPTPTVGLNSQPDTPRPEHTDQAQDEQPESLHSLIKSETEEWTRSQSDTRSDDDPVIKQHSKEVKEEEEEAGSDAEEGSVSEMKSGLEGDGAEDCGGEEDGDAVYLSEADGDTELDPPASESEDGYSMHTASSSIQLHTTADSIPSSPASSQFSICSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVHRPMDLSTIKKNIENGLIRTTAEFQRDIMLMFQNAVMYNSSDHDVFHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGREANRKQDPNDKDGGTRGRRCAIEADLKMKK", "length": 514, "header": "tr|A0AC58ICY5-1|A0AC58ICY5_DANRE Computationally mapped isoform of Bromodomain-containing protein 8 OS=Danio rerio OX=7955 GN=brd8a PE=4 SV=1 CANONICAL=A0A8M6Z376-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 490, "start_aa": "Thr", "end_pos": 490, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr490", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100003763", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003763", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ATL0-1", "protein_name": "Bromodomain-containing protein 8", "gene_name": "Brd8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATGTGKHKLLSTGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFAEPGRPPDWFSQKHCASQYSELLETTETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYRRLKRDAELIQAGHMDSRLDELCSDIAMKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTTMEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPVTDDSPQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVNESEMPVPSGHLSSTGVLLEVGGVLPMIHGGDIQPATSAVAASPAASGAPTLSRLLEAGPTQFSTPLPSFTTVASEPPVKLVPPPVESVSQATIVMMPALPAPSSAPAVSTPESVAPVSQPEPCVPLEAVGDPQTVTVSMDSSEISMIINSIKEECFRSGVAEAPGGSKAPSIDGKEDLDLAEKMDIAVSYTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQERLDFEESETKGIHELVDIRDSGVEIKVEPTEPEPGMSGAEIVAGVGPVPSLEPPELRSQDLDEEPRSSAAGEMGEADGSSGKGEERPLPAVKTEASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEEEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLGDSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSVPMGSPAFLLSLFVGCEWVWLDSGQDYPDDSELSNDCRSLFSSWDSSLDLDVGSWKDSEDADVEADELEESSPERESSELLVDDMESGEPQEEQDTQQNLLHLLSEEEALQDSKETGQGEGDASDGEDTPPLGEGRDGVRVQEAPLVNILYNCSNSSQLSDLSQGDPTQDHFLFKKTLLQVWKMIASHRFSSPFLKPVSEKQAPGYKDVVKRPMDLTTLKRNLSKGRIHTMAEFQRDLMLMFQNAVMYNDSDHHIYHMAVEMQREVLEQIQVLSTWLDKRKDLSSLE", "length": 1206 }, "evidence": [ { "id": "RGD:1307003", "url": "https://alliancegenome.org/gene/RGD:1307003#orthology", "database": "AGR" }, { "id": "HGNC:19874", "url": "https://alliancegenome.org/gene/HGNC:19874#orthology", "database": "AGR" }, { "id": "MGI:1925906", "url": "https://alliancegenome.org/gene/MGI:1925906#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091113-54", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-54#orthology", "database": "AGR" }, { "id": "FB:FBgn0039654", "url": "https://alliancegenome.org/gene/FB:FBgn0039654#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AB13AA18-1", "protein_name": "Bromodomain-containing protein 8", "gene_name": "brd8b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSTGMGKHKMLSLGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFSESGRPPDWFSQKHCASQYSQLLETTEAPKRKRGEKGEVVETIEDVIVRRLTAERIEELKRLIKDTQEKYRKLKKEVDLIQAGHVDPKLEELWAEIELKKKQEEEEAEQKKRATEAAYQIRQAAKNTPKRVPSVTVRSPPGASSPSMDILQPDASQPMTDESCASPMAQGVTVFMPVSDVMGPGPKESGLSSLVDDSPQKKHLAPKATPPPSPLLSELLKKGSLIAASSRLVVEGEVATGLSNGSHAVELHTSATVLPATQDITADAPTLSRLLESVTPAQQPVSADPPKPPTVVPPAPDHLSVPKSGDAAIAEGSGAEAVMAGSSTPAEVEGKETELVEEDTVVSVSYMGHELDLETVGDIIAIIEEKVDDPVEALDAAAVEAALSLCEDPAVGGHPLTSPWESQTFKAAEPEPMIQQSAIPAGAESAPNSAIVQGEMEVLVEEATETEAVEGVTEEPEVPSAPETEQSQDSEVKTEVERGGEGEGGVEETAQPENRTPSPAVKCEGEDWVQPETVTPCLDSEDSSASAKDAKEVKEEDGGSEVDVDEGMEMKECGDGDGEGPYLSEVDPPASESEDGYGSHSQRYTTADSTASSPASSQFSMCSEDQEALQAQKIWKKAIMLVWRAAANHRYASVFLQPVSDDIAPGYHSIVHRPMDLSAIKKNIESGQIRTTAEFQRDIMLMFQNAVMYNSSDHDVYHMALEMQRDVLEQIQQFLATQLIMQTSESGISTKSLRGREANRKQDPNEKTLSPAHKEPHLEPEPPARRKRNNSKQDTVEKDSLSMASPAFLLSLFDGGTRGRRSAIEADMKMKK", "length": 864 }, "evidence": [ { "id": "RGD:1307003", "url": "https://alliancegenome.org/gene/RGD:1307003#orthology", "database": "AGR" }, { "id": "HGNC:19874", "url": "https://alliancegenome.org/gene/HGNC:19874#orthology", "database": "AGR" }, { "id": "MGI:1925906", "url": "https://alliancegenome.org/gene/MGI:1925906#orthology", "database": "AGR" }, { "id": "FB:FBgn0039654", "url": "https://alliancegenome.org/gene/FB:FBgn0039654#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3X9B4-1", "protein_name": "BRD8 domain containing", "gene_name": "Brd8dc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCLQAGCEWVWLDSGQDSHDDSELSNDCRSLLSSWDSSLDLDVGSWKDTEDAEAEADEPKESSPERGCSELLVGDVESEEAREEAEQGTPQELLSEGEAQQDSKEDDQGEGSASDGEDTPPLGEGEGIRVQEAPLVNILYSSSQLNDLSQGDPIQDQFLFKKTLLQVWKMIASHRFSSPFLKPVSEKQAPGYKDVVKRPMDLTTLKRNLSKGRIHTMAEFQRDLMLMFQNAVMYNDSDHHIYHMAVEMQREVLEQIQVLSTWLDKRKDLSSLE", "length": 273 }, "evidence": [ { "id": "FB:FBgn0039654", "url": "https://alliancegenome.org/gene/FB:FBgn0039654#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R3B7-1", "protein_name": "Bromodomain-containing protein 8", "gene_name": "Brd8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATGTGKHKLLSTGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFAEPGRPPDWFSQKHCASQYSELLETTETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYRRLKRDAELIQAGHMDSRLDELCNDIAMKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPVDSASPGGDYPLGDLTPTTMEEATSGVTPGTLPSTPVTSFPGIPDTLPPGSAPLEAPMTPITDDSPQKKMLGQKATPPPSPLLSELLKKGSLLPTSPRLVNESEMPVPPGHLNSTGVLLEVGGVLPMIHGGEIQPTTSAVAASPAASGAPTLSRLLEAGPTQFTTPLPSFTTVASEPPVKLVPPPVESVSQATIVMMPALPAPSSAAAVSTSESGAPVSQPEPCVPLEAVGDPHTVTVSMDSNEISMIINSIKEECFRSGVAEAPGGSKAPSIDGKEDLDLAEKMDIAVSYTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQERLDFEESENKGLHDLVDIRDSGVEIKVEPTEPEPGMSGAEIVAGVGPVPSMEPPELRSQDSDEEPRSSAAGDIGEADGSSGKGDERPLSAVKTEASPESMLSPSHGSNLIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGDDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSVPMGSPAFLLSLFDGGTRGRRCAIEADMKMKK", "length": 951 }, "evidence": [ { "id": "RGD:1307003", "url": "https://alliancegenome.org/gene/RGD:1307003#orthology", "database": "AGR" }, { "id": "HGNC:19874", "url": "https://alliancegenome.org/gene/HGNC:19874#orthology", "database": "AGR" }, { "id": "MGI:1925906", "url": "https://alliancegenome.org/gene/MGI:1925906#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091113-54", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-54#orthology", "database": "AGR" }, { "id": "FB:FBgn0039654", "url": "https://alliancegenome.org/gene/FB:FBgn0039654#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0E9-1", "protein_name": "Bromodomain-containing protein 8", "gene_name": "BRD8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGTGKHKLLSTGPTEPWSIREKLCLASSVMRSGDQNWVSVSRAIKPFAEPGRPPDWFSQKHCASQYSELLETTETPKRKRGEKGEVVETVEDVIVRKLTAERVEELKKVIKETQERYRRLKRDAELIQAGHMDSRLDELCNDIATKKKLEEEEAEVKRKATDAAYQARQAVKTPPRRLPTVMVRSPIDSASPGGDYPLGDLTPTTMEEATSGVNESEMAVASGHLNSTGVLLEVGGVLPMIHGGEIQQTPNTVAASPAASGAPTLSRLLEAGPTQFTTPLASFTTVASEPPVKLVPPPVESVSQATIVMMPALPAPSSAPAVSTTESVAPVSQPDNCVPMEAVGDPHTVTVSMDSSEISMIINSIKEECFRSGVAEAPVGSKAPSIDGKEELDLAEKMDIAVSYTGEELDFETVGDIIAIIEDKVDDHPEVLDVAAVEAALSFCEENDDPQSLPGPWEHPIQQERDKPVPLPAPEMTVKQERLDFEETENKGIHELVDIREPSAEIKVEPAEPEPVISGAEIVAGVVPATSMEPPELRSQDLDEELGSTAAGEIVEADVAIGKGDETPLTNVKTEASPESMLSPSHGSNPIEDPLEAETQHKFEMSDSLKEESGTIFGSQIKDAPGEDEEEDGVSEAASLEEPKEEDQGEGYLSEMDNEPPVSESDDGFSIHNATLQSHTLADSIPSSPASSQFSVCSEDQEAIQAQKIWKKAIMLVWRAAANHRYANVFLQPVTDDIAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVMYNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSVPMGSPAFLLSLFMGHEWVWLDSEQDHPNDSELSNDCRSLFSSWDSSLDLDVGNWRETEDPEAEELEESSPEREPSELLVGDGGSEESQEAARKASHQNLLHFLSEVAYLMEPLCISSNESSEGCCPPSGTRQEGREIKASEGERELCRETEELSAKGDPLVAEKPLGENGKPEVASAPSVICTVQGLLTESEEGEAQQESKGEDQGEVYVSEMEDQPPSGECDDAFNIKETPLVDTLFSHATSSKLTDLSQDDPVQDHLLFKKTLLPVWKMIASHRFSSPFLKPVSERQAPGYKDVVKRPMDLTSLKRNLSKGRIRTMAQFLRDLMLMFQNAVMYNDSDHHVYHMAVEMRQEVLEQIQVLNIWLDKRKGSSSLEGEPANPVDDGKPVF", "length": 1235 }, "evidence": [ { "id": "RGD:1307003", "url": "https://alliancegenome.org/gene/RGD:1307003#orthology", "database": "AGR" }, { "id": "HGNC:19874", "url": "https://alliancegenome.org/gene/HGNC:19874#orthology", "database": "AGR" }, { "id": "MGI:1925906", "url": "https://alliancegenome.org/gene/MGI:1925906#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091113-54", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-54#orthology", "database": "AGR" }, { "id": "FB:FBgn0039654", "url": "https://alliancegenome.org/gene/FB:FBgn0039654#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VAM5-1", "protein_name": "Bromodomain-containing protein 8", "gene_name": "Brd8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSAGVQERLQLSRMPLDTWSKREQLILASAVSCSGDQNWITVSRTLKTICGNGSSNRPADWFSQKNCAMQYGNLLESVEATKRKKRSSESSAGVSSPATVETPTELLLRRLTEERQAEIKAQMRQDQETYRRIQREIESLQSDAVTEQELQDMWLEIEKEQEARRIEEMKLENRMREREQRKKDLASNWRNSSLAVKRSNQAADTTSVDMDVEDINTSGNGKQQTGPSPLLTSLLKSPTGNAPATPTPGGAAPAAGGTGSVARATAPTITSLLTSGPSSAVANQPVITMKSPTDAAFMSRPITGPPASEASTTPTLERSPSQAAPTLSMLLEKNMAAAKANESGSLVKPEGSGNQEQGVDEATSSAAGTADSDEADPNEAQLLEVFKNIDQIIDDIDIDMASVIDDEILKNVDDVVASPSNDKAEVIDFEDKLDALKREQSKSSPASDKPKSVELVIGSSDDSNDNIPLAAVASQESKDRGQSGGESTRGTEDAESEPLTSEVAVEEIGETITIISTSSEDTAGSPPTKMEEDGATDSLPKKEDAAEDKSEQESSSQGQNKAGGSTDEPELIDHQATREAQSKSGKDTAGKPVTMQEKTTTQSAPVPVDLHDTDEESSSLTDSSKHDDHPRSAKAKPPALKLALDDSKSELELSGTPQPPSAPARTPLLRKLPHRDRSESPMVDDDATTASDHSTARSTRRRCSSTPVIDSIPNSPASSEHTDDRRETRAASKKLFLSIYAMLLDSKHAAPFKRPFHDEHAQRHADLCLRPMDFPTIKRNIDSGFIRSLSELHRDVLLMAHNVLVAYKPHTAQHKTARLFVQDCQAIKEFSQLPDVQAGITATPVSNTGSLRADKSSGSKARSGSRKSQRHH", "length": 872 }, "evidence": [ { "id": "RGD:1307003", "url": "https://alliancegenome.org/gene/RGD:1307003#orthology", "database": "AGR" }, { "id": "HGNC:19874", "url": "https://alliancegenome.org/gene/HGNC:19874#orthology", "database": "AGR" }, { "id": "MGI:1925906", "url": "https://alliancegenome.org/gene/MGI:1925906#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091113-54", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-54#orthology", "database": "AGR" }, { "id": "FB:FBgn0039654", "url": "https://alliancegenome.org/gene/FB:FBgn0039654#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z376", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376" } ], "pmid": "" }, { "name": "NuA4 histone acetyltransferase complex", "id": "GO:0035267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035267", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z376", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z376", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z376", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 729, "end_pos": 731, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z376", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z376" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 666, "end_pos": 736, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 490 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 729, "end_pos": 731 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z3P8-1", "uniprot_ac": "A0A8M6Z3P8", "uniprot_id": "A0A8M6Z3P8_DANRE", "mass": { "chemical_mass": 57038.0, "monoisotopic_mass": 57038.0 }, "refseq": { "ac": "XP_017209018", "name": "myosin binding protein Ha isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209018" }, "gene_names": [ { "name": "mybpha", "type": "recommended", "evidence": [ { "id": "A0A8M6Z3P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8" } ] }, { "name": "mybpha", "type": "synonym", "evidence": [ { "id": "XP_017209018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209018" } ] }, { "name": "zgc:66097", "type": "synonym", "evidence": [ { "id": "XP_017209018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209018" }, { "id": "A0A8M6Z3P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8" } ] }, { "name": "zgc:85883", "type": "synonym", "evidence": [ { "id": "XP_017209018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209018" }, { "id": "A0A8M6Z3P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8" } ] }, { "name": "zgc:91966", "type": "synonym", "evidence": [ { "id": "XP_017209018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209018" }, { "id": "A0A8M6Z3P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8" } ] } ], "protein_names": [ { "name": "Myosin-binding protein H", "type": "recommended", "evidence": [ { "id": "A0A8M6Z3P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8/entry#names_and_taxonomy" } ] }, { "name": "H-protein", "type": "synonym", "evidence": [ { "id": "A0A8M6Z3P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8/entry#names_and_taxonomy" } ] }, { "name": "myosin binding protein Ha isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017209018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209018" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017209018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209018" } ] }, { "annotation": "Binds to myosin; probably involved in interaction with thick myofilaments in the A-band.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YVU2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YVU2#function" }, { "database": "UniProtKB", "id": "ARBA00060255", "url": "https://www.uniprot.org/uniprotkb/ARBA00060255#function" }, { "database": "UniProtKB", "id": "A0A8M6Z3P8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8#function" }, { "database": "UniProtKB", "id": "A0AC58IJ79", "url": "https://www.uniprot.org/uniprotkb/A0AC58IJ79#function" }, { "database": "UniProtKB", "id": "A0AC58IJA4", "url": "https://www.uniprot.org/uniprotkb/A0AC58IJA4#function" } ] } ], "disease": [ { "disease_id": "DOID:10763", "recommended_name": { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hypertension", "description": "An artery disease characterized by chronic elevated blood pressure in the arteries." }, "synonyms": [ { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "HTN", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "hyperpiesia", "description": "" }, { "id": "DOID:10763", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10763", "name": "vascular hypertensive disorder", "description": "" } ], "unlinked_id_list": [ "DOID:13731", "DOID:11130" ], "evidence": [ { "id": "10763", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10763" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3P8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mybpha", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040426-1531", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1531", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z3P8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z3P8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05748", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05748", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "393530", "url": "https://www.ncbi.nlm.nih.gov/gene/393530", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050964", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050964", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YVU2", "url": "https://www.orthodb.org/?gene=A0A8M6YVU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z3P8", "url": "https://www.orthodb.org/?gene=A0A8M6Z3P8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13817", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13817", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13817:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13817:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017209018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209018", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YVU2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YVU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YVU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YVU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3P8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IJ79", "url": "https://www.uniprot.org/uniprotkb/A0AC58IJ79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IJ79-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IJ79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IJA4", "url": "https://www.uniprot.org/uniprotkb/A0AC58IJA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IJA4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IJA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040426-1531", "url": "https://zfin.org/ZDB-GENE-040426-1531", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPAKPAPIKKSAKKAAEKEEKPAAPAPVPETAPVEAPPAEDPPVEAAAPAAVEETTPAPEAPVAEGPAEETAPAADAPAEAAPAEPAPVEEPPKAPTPPPPAVPPSAPQGLSVDDVNDTSVTLKWRSPENIGSGLDGYAVEYCKEGSSEWVVANTELVTSNRHAIRGLTTGDMLNIRVVAVNAGGRSEPVVLPQPIPVREVMDRPRIRMPRALRSKYIRHAGEQINLVIPFSGKPKPVISWTKNGQPLDTKKVNVRNSDKDSILFIRKAERDDSGSYEMSVKVDSFEDKTTLIIQIVDLPGPPVSVKLVDSWGFNAALEWTPPKDNGNTEITGYTVQKADKKTGEWFTVLEHFHRLNVTVTDLVMGNVYTFRVFSENMVGRSETAAVTKDAARIKKTVPAEVVVPLSVGIVYKPLEYKEHDFSEAPKFTAPLKDRAATVGYTAKLLCAVRGSPKPKIEWLKNQMLLGDDPKFRQINNQGVCSLEIRKPSSFDGGVYTCRAKNALGEATVACKLEVKQVTIQEEKDKK", "length": 527, "header": "tr|A0A8M6Z3P8-1|A0A8M6Z3P8_DANRE Isoform 1 of Myosin-binding protein H OS=Danio rerio OX=7955 GN=mybpha PE=1 SV=1 CANONICAL=A0A8M6Z3P8-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YVU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8/entry#A0A8M6YVU2-1", "sequence": { "sequence": "MPAKPAPIKKSAKKAAEKEEKPAAPAPVPETAPVEAPPAEDPPVEAAAPAAVEETTPAPEAPVAEAAPAEPAPVEEPPKAPTPPPPAVPPSAPQGLSVDDVNDTSVTLKWRSPENIGSGLDGYAVEYCKEGSSEWVVANTELVTSNRHAIRGLTTGDMLNIRVVAVNAGGRSEPVVLPQPIPVREVMDRPRIRMPRALRSKYIRHAGEQINLVIPFSGKPKPVISWTKNGQPLDTKKVNVRNSDKDSILFIRKAERDDSGSYEMSVKVDSFEDKTTLIIQIVDLPGPPVSVKLVDSWGFNAALEWTPPKDNGNTEITGYTVQKADKKTGEWFTVLEHFHRLNVTVTDLVMGNVYTFRVFSENMVGRSETAAVTKDAARIKKTVPAEVVVPLSVGIVYKPLEYKEHDFSEAPKFTAPLKDRAATVGYTAKLLCAVRGSPKPKIEWLKNQMLLGDDPKFRQINNQGVCSLEIRKPSSFDGGVYTCRAKNALGEATVACKLEVKQVTIQEEKDKK", "length": 512, "header": "tr|A0A8M6YVU2-1|A0A8M6Z3P8_DANRE Computationally mapped isoform of Myosin-binding protein H OS=Danio rerio OX=7955 GN=mybpha PE=1 SV=1 CANONICAL=A0A8M6Z3P8-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z3P8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8/entry#A0A8M6Z3P8-1", "sequence": { "sequence": "MPAKPAPIKKSAKKAAEKEEKPAAPAPVPETAPVEAPPAEDPPVEAAAPAAVEETTPAPEAPVAEGPAEETAPAADAPAEAAPAEPAPVEEPPKAPTPPPPAVPPSAPQGLSVDDVNDTSVTLKWRSPENIGSGLDGYAVEYCKEGSSEWVVANTELVTSNRHAIRGLTTGDMLNIRVVAVNAGGRSEPVVLPQPIPVREVMDRPRIRMPRALRSKYIRHAGEQINLVIPFSGKPKPVISWTKNGQPLDTKKVNVRNSDKDSILFIRKAERDDSGSYEMSVKVDSFEDKTTLIIQIVDLPGPPVSVKLVDSWGFNAALEWTPPKDNGNTEITGYTVQKADKKTGEWFTVLEHFHRLNVTVTDLVMGNVYTFRVFSENMVGRSETAAVTKDAARIKKTVPAEVVVPLSVGIVYKPLEYKEHDFSEAPKFTAPLKDRAATVGYTAKLLCAVRGSPKPKIEWLKNQMLLGDDPKFRQINNQGVCSLEIRKPSSFDGGVYTCRAKNALGEATVACKLEVKQVTIQEEKDKK", "length": 527, "header": "tr|A0A8M6Z3P8-1|A0A8M6Z3P8_DANRE Isoform 1 of Myosin-binding protein H OS=Danio rerio OX=7955 GN=mybpha PE=1 SV=1 CANONICAL=A0A8M6Z3P8-1" }, "locus": {} }, { "isoform_ac": "A0AC58IJ79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8/entry#A0AC58IJ79-1", "sequence": { "sequence": "MLNIRVVAVNAGGRSEPVVLPQPIPVREVMDRPRIRMPRALRSKYIRHAGEQINLVIPFSGKPKPVISWTKNGQPLDTKKVNVRNSDKDSILFIRKAERDDSGSYEMSVKVDSFEDKTTLIIQIVDLPGPPVSVKLVDSWGFNAALEWTPPKDNGNTEITGYTVQKADKKTGEWFTVLEHFHRLNVTVTDLVMGNVYTFRVFSENMVGRSETAAVTKDAARIKKTVPAEVVVPLSVGIVYKPLEYKEHDFSEAPKFTAPLKDRAATVGYTAKLLCAVRGSPKPKIEWLKNQMLLGDDPKFRQINNQGVCSLEIRKPSSFDGGVYTCRAKNALGEATVACKLEVKQVTIQEEKDKK", "length": 355, "header": "tr|A0AC58IJ79-1|A0AC58IJ79_DANRE Computationally mapped isoform of Myosin-binding protein H OS=Danio rerio OX=7955 GN=mybpha PE=1 SV=1 CANONICAL=A0A8M6Z3P8-1" }, "locus": {} }, { "isoform_ac": "A0AC58IJA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8/entry#A0AC58IJA4-1", "sequence": { "sequence": "MLNIRVVAVNAGGRSEPVVLPQPIPVREVMDRPRIRMPRALRSKYIRHAGEQINLVIPFSGKPKPVISWTKNGQPLDTKKVNVRNSDKDSILFIRKAERDDSGSYEMSVKVDSFEDKTTLIIQIVDLPGPPVSVKLVDSWGFNAALEWTPPKDNGNTEITGYTVQKADKKTGEWFTVLEHFHRLNVTVTDLVMGNVYTFRVFSENMVGRSETAAVTKDAARIKKTGIVYKPLEYKEHDFSEAPKFTAPLKDRAATVGYTAKLLCAVRGSPKPKIEWLKNQMLLGDDPKFRQINNQGVCSLEIRKPSSFDGGVYTCRAKNALGEATVACKLEVKQVTIQEEKDKK", "length": 344, "header": "tr|A0AC58IJA4-1|A0AC58IJA4_DANRE Computationally mapped isoform of Myosin-binding protein H OS=Danio rerio OX=7955 GN=mybpha PE=1 SV=1 CANONICAL=A0A8M6Z3P8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 97, "start_aa": "Thr", "end_pos": 97, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr97", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A2RUH7-1", "protein_name": "Myosin-binding protein H-like", "gene_name": "MYBPHL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAATAPEVAAGSKLKVKEASPADAEPPQASPGQGAGSPTPQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHDGCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADCTTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGIYTCKAVNPLGEASVDCRVDVKVPN", "length": 354 }, "evidence": [ { "id": "HGNC:30434", "url": "https://alliancegenome.org/gene/HGNC:30434#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1531", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1531#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88599-1", "protein_name": "Myosin-binding protein H", "gene_name": "Mybph", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGKATPEASVSTSEGTAPEPAKVPTPEPSGQVAASESTGQEQAPEPQKQPQAQDPAAHEAPATPATTKPEAPSEDVPSAPLQLTLEDVSHSSLTVSWEPPEDLGSWGSRAMCWSSVREGASEWVPVNPRPVMVTQQTVRNLALGDKFFLRVTAVNSAGAGPPAVLDQPVHIQEITEAPKIRVPRHLRQTYIRQVGESVNLQIPFQGKPKPQASWTHNGHALDSQRVNVRSGDQDSILFIRSAQRSDSGRYELTVRLEGLEAKAAIDILVIEKPGPPSSIKLLDVWGCNAALEWMPPQDTGNTELLGYTVQKADKKTGQWFTVLERYHPTTCTVSDLIIGNSYSFRVFSENLCGLSDLATTTKELAHIHKAAITAKPREFTERDFSEPPSFTQPVADRTSTPGYSTQLFCSVRASPKPKIIWMKNKMSIQGDPKYRAVSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEPAVDCRLEVKASATH", "length": 484 }, "evidence": [ { "id": "RGD:620287", "url": "https://alliancegenome.org/gene/RGD:620287#orthology", "database": "AGR" }, { "id": "HGNC:7552", "url": "https://alliancegenome.org/gene/HGNC:7552#orthology", "database": "AGR" }, { "id": "MGI:1858196", "url": "https://alliancegenome.org/gene/MGI:1858196#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1531", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1531#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70402-1", "protein_name": "Myosin-binding protein H", "gene_name": "Mybph", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGKATSEASVSTPEETAPEPAKVPTTEPSGEVAASESTGQEQAPEPQKPQAQDPAAPAASAMPAATKPEPPSEDVPSAPLRLTLEDVSHSSLTVSWEPPEKLGKLGLQGYVLEFCREGASEWVPVNPRPVMVTQQTVRNLALGDKFFLRVTAVSSAGAGPPAVLDQPVHIQEITEAPKIRVPRHLRQTYIRQVGESVNLQIPFQGKPKPQVSWTHNGHALDNQRVNVRSGDQDSILFIRSAQRADSGRYELTVHLEGLEAKASIDILVIEKPGPPSSIKLLDVWGCNAALEWTPPQDTGNTELLGYTVQKADKRTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSDLATTTKELAHIHKADITAKPREFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMDIQGDPKYRAVSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASATH", "length": 483 }, "evidence": [ { "id": "RGD:620287", "url": "https://alliancegenome.org/gene/RGD:620287#orthology", "database": "AGR" }, { "id": "HGNC:7552", "url": "https://alliancegenome.org/gene/HGNC:7552#orthology", "database": "AGR" }, { "id": "MGI:1858196", "url": "https://alliancegenome.org/gene/MGI:1858196#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1531", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1531#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q13203-1", "protein_name": "Myosin-binding protein H", "gene_name": "MYBPH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMEKNTSEGPACSPEETASESAKVPTAEPPGEVAVSESTREEQVPKPQAPAPQAPTASTATKPAPPSEDVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIRENIEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRASPKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCRLEVKASAAH", "length": 477 }, "evidence": [ { "id": "RGD:620287", "url": "https://alliancegenome.org/gene/RGD:620287#orthology", "database": "AGR" }, { "id": "HGNC:7552", "url": "https://alliancegenome.org/gene/HGNC:7552#orthology", "database": "AGR" }, { "id": "MGI:1858196", "url": "https://alliancegenome.org/gene/MGI:1858196#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1531", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1531#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5FW53-1", "protein_name": "Myosin-binding protein H-like", "gene_name": "Mybphl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METATTLEIASCSQRQVEAAADPADAKGPRTSHQQEAGSPSLQLLPSIEEHPKIWLPRALKQTYIRKAGETVNLLIPIQGKPKPQTTWTHNGCALDSSRVSVRNGEHDSILFIREAQRTDSGCYQLCVQLGGLQATATINILVIEKPGPPQSIKLVDVWGANATLEWTPPQDTGNTALLGYTVQKADKKSGLWFTVLERYHRTSCVVSNLIVGNSYAFRVFAENQCGLSDTAPVTADLAHIQKAATVYKAKGFAQRDLSEAPKFTQPLADCTTVTGYDTQLFCCVRASPRPKIIWLKNKMDLQGNPKYRALSQLGICSLEIRKPSPFDGGIYTCKAINALGEASVDCRVDVKAPH", "length": 355 }, "evidence": [ { "id": "HGNC:30434", "url": "https://alliancegenome.org/gene/HGNC:30434#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5PQM4-1", "protein_name": "Myosin-binding protein H-like", "gene_name": "Mybphl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METATTLEIASCSQRQVEEAADPADAEGPQTTRQQEAGSPSLQLLPSIEEHPKIWLPRALRQTYIRKVGETVNLLIPFQGKPKPQTIWTHNGSALDNSRVSVRNGEHDSILFIREAQRTDSGCYQLCVQLGGLQATATINILVIEKPGPPQSIKLVDVWGANATLEWTPPQDTGNTALLGYTVQKADKKSGLWFTVLERYHRTSCIVSDLIVGNSYAFRVFAENQCGLSDTAPVTADLAHIQKAATVYKAKGFAQRDLSEAPKFTQPLADCTTVTGYDTQLFCCVRASPKPKIIWLKNKMDLQGNPKYRALSQLGICSLEIRKPSPFDGGIYTCKAINALGEASVDCRVDVKAPH", "length": 355 }, "evidence": [ { "id": "HGNC:30434", "url": "https://alliancegenome.org/gene/HGNC:30434#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VZT8-1", "protein_name": "Myomesin and myosin binding protein", "gene_name": "MnM", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGNQPGKLHTHPQGGRPKKNVHWKSAERPSPPGRPILTPVALPEQQPDVVNLRWDRPLHDGGSPITGYTVEHRRMGSPHWVRATPTPVDRCDVCISGLEPGWRYQFRCFAENIVGRSDASELSDPLTVTLQRNAITVPRFIDELVDTNAVEDERIEFRVRILGEPPPEINWFKDGYEIFSSRRTKIVNDNEASVLVIHQVALTDEGEIKCTATNRAGHVITKARLMVQAPPKIRLPRTYEDGLIVEADEVLRLKVGVAGQPPPAITWLHEGEVIAPGGRFEVSNTEKNSLLKIDNVLREDRGEYMVKAWNRLGEDSTSFLVTVTARPNPPGTPKLNMSFGKSATLSWTAPLDDGGCKIGNYIVEYFRVGWNVWLKAATTRALSTTLHDLIEGSEYKFRVKAENPYGLSEPSGESELLFIPDPKRGITKPKSATRIAGDEKDKPKTGAGGMQVPPRRKTLSPPRPQADASTGMSPKQSPSAKRKPKPQLIDNEQLTHEMSYGTSDHALKMDVRKSPSLNSADSANKPTTDSSNPKLNLTLVTTTLAPLDKSVPSPKAPRTPATSPLKLFNPKPSGAPKDRSPVQPKPQPLPTPPMETPDKASPNPKRSLSPPNKRQPPPLRKSPTPPEPIKVTPALLRSAEPVQLGVNQNVRRFSGQTLSPARNVPTLALAVASGVSAVIGEKLPTIEISAPPTPQEEEPPVLERSPSPEPAPKSQSNARRFSRSADKHDDVHTSNEFMLVVFDKNSKVKDKDKQDSFELDLEDAIQPPPISISAPDLAFLEFTNLHTTFPLRRSVSSTELLYERAMARFYEAVELEQASKSRKTSRDKLVTPVPHQTPANLRKRLGSISEAERLSFERRSEMRRQSADVVSISRKWDSRENVNEMGNLTRIHTTGQLPFETRKDLRESEAEEEHEEGEEEHLTESTADDSEDMDLDYDEDLDVDYPPQKKLQQQSSNDLGSDYTESTASSEQDSIEKFKMELLARTRSPSPRDLETYHPRTMGAGTFTPYRAPTPEQAAVVLNRPVPLPSPDFVPKPILKRSSNEHMEQAVSPLPSSFASEAPTIIVPPTATVANSNPSTLKMDLAKGIKSFFSRDKRSATEKNTEANEEISNPLERTNAAAIAADLEVKRKAKEEEELRRKEEERLMQEEAHAAVDHYSDLVKEVGSSHKYHTPLYLDRDELKRAAAKAAAETDEEDMLTHAEELKKRRATGGSEDLFLAPPVVRERRLSISEREQLVHVRDAASSLAFHRSPEKPESDQEHESPKSQQDEEPEYPTVLVVPPPKSKNKNESETESVMSEMVEARPDARGRTRLVKVKRVIRRRVPSSTRSRDASLTRPAIAEVEGSQQTSLVLSAADRDLLQKAATLAILQSEEQAHEKVRSALSYCTDLVLFLVACYVYLFKDARLVLPILGLIIYRQLGEAVRGYVPGWLRRRFTGNGS", "length": 1443 }, "evidence": [ { "id": "RGD:620287", "url": "https://alliancegenome.org/gene/RGD:620287#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3P8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8" } ], "pmid": "" }, { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3P8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "myosin filament", "id": "GO:0032982", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032982", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3P8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8" } ], "pmid": "" }, { "name": "M band", "id": "GO:0031430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031430", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3P8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of muscle", "id": "GO:0008307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008307", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3P8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z3P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 107, "end_pos": 201, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z3P8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3P8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 205, "end_pos": 293, "start_aa": "Pro", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 97 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 357, "end_pos": 359 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PFK0-1", "uniprot_ac": "A0A8M9PFK0", "uniprot_id": "A0A8M9PFK0_DANRE", "mass": { "chemical_mass": 80740.0, "monoisotopic_mass": 80740.0 }, "refseq": { "ac": "XP_021325673", "name": "segment polarity protein dishevelled homolog DVL-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325673" }, "gene_names": [ { "name": "dvl1a", "type": "recommended", "evidence": [ { "id": "A0A8M9PFK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0" } ] }, { "name": "dvl1a", "type": "synonym", "evidence": [ { "id": "XP_021325673", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325673" } ] } ], "protein_names": [ { "name": "Segment polarity protein dishevelled homolog DVL-1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PFK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#names_and_taxonomy" } ] }, { "name": "segment polarity protein dishevelled homolog DVL-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325673", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325673" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325673" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dvl1a", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0", "locus": {} } ], "crossref": [ { "id": "A0A8M9PFK0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PFK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04438", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04438", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06717", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06717", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "569863", "url": "https://www.ncbi.nlm.nih.gov/gene/569863", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024580", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024580", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569863", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569863", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6YW38", "url": "https://www.orthodb.org/?gene=A0A8M6YW38", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YXZ6", "url": "https://www.orthodb.org/?gene=A0A8M6YXZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z4M4", "url": "https://www.orthodb.org/?gene=A0A8M6Z4M4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PFK0", "url": "https://www.orthodb.org/?gene=A0A8M9PFK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10878", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10878", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10878:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10878:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00778", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00778", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02377", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02377", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12316", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12316", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325673", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YW38", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YW38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YW38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YW38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YXZ6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YXZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YXZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YXZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4M4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4M4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4M4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PL94", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PL94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PWX8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PWX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PWX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PWX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILW9", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILX0", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILX0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILY4", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILY4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILZ6", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IM08", "url": "https://www.uniprot.org/uniprotkb/A0AC58IM08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IM08-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IM08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IM20", "url": "https://www.uniprot.org/uniprotkb/A0AC58IM20", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IM20-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IM20-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREGEFPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASSHRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMVLSVFVTEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSEGSRSSGSNPSAGKGRRASPREKEHKAPCCGGSESELVTWVTRRGEKAPSQLSHQSHSRSAASQSQSAYSHGHTQCHLIPQHSLSFSYSHAPFIQPSHLSCAHSERSHGSSYGPPGLPPPYCLAHLAPKTAAGNSNSPPGAPPIREIGNVPPELTASRQSFQHAMGNPCEFFVDIM", "length": 738, "header": "tr|A0A8M9PFK0-1|A0A8M9PFK0_DANRE Isoform 1 of Segment polarity protein dishevelled homolog DVL-1 isoform X1 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YW38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#A0A8M6YW38-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREGEFPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASSHRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSEGSRSSGSNPSAGKGRRASPREKEHKAPCCGGSESELVTWVTRRGEKAPSQLSHQSHSRSAASQSQSAYSHGHTQCHLIPQHSLSFSYSHAPFIQPSHLSCAHSERSHGSSYGPPGLPPPYCLAHLAPKTAAGNSNSPPGAPPIREIGNVPPELTASRQSFQHAMGNPCEFFVDIM", "length": 731, "header": "tr|A0A8M6YW38-1|A0A8M9PFK0_DANRE Computationally mapped isoform of Segment polarity protein dishevelled homolog DVL-1 isoform X1 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "locus": {} }, { "isoform_ac": "A0A8M6YXZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#A0A8M6YXZ6-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREGEFPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSEGSRSSGSNPSAGKGRRASPREKEHKAPCCGGSESELVTWVTRRGEKAPSQLSHQSHSRSAASQSQSAYSHGHTQCHLIPQHSLSFSYSHAPFIQPSHLSCAHSERSHGSSYGPPGLPPPYCLAHLAPKTAAGNSNSPPGAPPIREIGNVPPELTASRQSFQHAMGNPCEFFVDIM", "length": 729, "header": "tr|A0A8M6YXZ6-1|A0A8M9PFK0_DANRE Computationally mapped isoform of Segment polarity protein dishevelled homolog DVL-1 isoform X1 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z4M4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#A0A8M6Z4M4-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREVPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSEGSRSSGSNPSAGKGRRASPREKEHKAPCCGGSESELVTWVTRRGEKAPSQLSHQSHSRSAASQSQSAYSHGHTQCHLIPQHSLSFSYSHAPFIQPSHLSCAHSERSHGSSYGPPGLPPPYCLAHLAPKTAAGNSNSPPGAPPIREIGNVPPELTASRQSFQHAMGNPCEFFVDIM", "length": 727, "header": "tr|A0A8M6Z4M4-1|A0A8M6Z4M4_DANRE Computationally mapped isoform of Segment polarity protein dishevelled homolog DVL-1 isoform X8 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PFK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#A0A8M9PFK0-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREGEFPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASSHRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMVLSVFVTEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSEGSRSSGSNPSAGKGRRASPREKEHKAPCCGGSESELVTWVTRRGEKAPSQLSHQSHSRSAASQSQSAYSHGHTQCHLIPQHSLSFSYSHAPFIQPSHLSCAHSERSHGSSYGPPGLPPPYCLAHLAPKTAAGNSNSPPGAPPIREIGNVPPELTASRQSFQHAMGNPCEFFVDIM", "length": 738, "header": "tr|A0A8M9PFK0-1|A0A8M9PFK0_DANRE Isoform 1 of Segment polarity protein dishevelled homolog DVL-1 isoform X1 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PL94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#A0A8M9PL94-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREGEFPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMVLSVFVTEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSEGSRSSGSNPSAGKGRRASPREKEHKAPCCGGSESELVTWVTRRGEKAPSQLSHQSHSRSAASQSQSAYSHGHTQCHLIPQHSLSFSYSHAPFIQPSHLSCAHSERSHGSSYGPPGLPPPYCLAHLAPKTAAGNSNSPPGAPPIREIGNVPPELTASRQSFQHAMGNPCEFFVDIM", "length": 736, "header": "tr|A0A8M9PL94-1|A0A8M9PL94_DANRE Computationally mapped isoform of Segment polarity protein dishevelled homolog DVL-1 isoform X2 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PWX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#A0A8M9PWX8-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREVPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASSHRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMVLSVFVTEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSEGSRSSGSNPSAGKGRRASPREKEHKAPCCGGSESELVTWVTRRGEKAPSQLSHQSHSRSAASQSQSAYSHGHTQCHLIPQHSLSFSYSHAPFIQPSHLSCAHSERSHGSSYGPPGLPPPYCLAHLAPKTAAGNSNSPPGAPPIREIGNVPPELTASRQSFQHAMGNPCEFFVDIM", "length": 736, "header": "tr|A0A8M9PWX8-1|A0A8M9PFK0_DANRE Computationally mapped isoform of Segment polarity protein dishevelled homolog DVL-1 isoform X1 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "locus": {} }, { "isoform_ac": "A0AC58ILW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#A0AC58ILW9-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREGEFPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSED", "length": 555, "header": "tr|A0AC58ILW9-1|A0AC58ILW9_DANRE Computationally mapped isoform of Segment polarity protein dishevelled homolog DVL-1 isoform X11 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "locus": {} }, { "isoform_ac": "A0AC58ILX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#A0AC58ILX0-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREVPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSED", "length": 553, "header": "tr|A0AC58ILX0-1|A0AC58ILX0_DANRE Computationally mapped isoform of Segment polarity protein dishevelled homolog DVL-1 isoform X12 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "locus": {} }, { "isoform_ac": "A0AC58ILY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#A0AC58ILY4-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREVPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASSHRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSEGSRSSGSNPSAGKGRRASPREKEHKAPCCGGSESELVTWVTRRGEKAPSQLSHQSHSRSAASQSQSAYSHGHTQCHLIPQHSLSFSYSHAPFIQPSHLSCAHSERSHGSSYGPPGLPPPYCLAHLAPKTAAGNSNSPPGAPPIREIGNVPPELTASRQSFQHAMGNPCEFFVDIM", "length": 729, "header": "tr|A0AC58ILY4-1|A0AC58ILY4_DANRE Computationally mapped isoform of Segment polarity protein dishevelled homolog DVL-1 isoform X7 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "locus": {} }, { "isoform_ac": "A0AC58ILZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#A0AC58ILZ6-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREGEFPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASSHRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMVLSVFVTEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSED", "length": 564, "header": "tr|A0AC58ILZ6-1|A0AC58ILZ6_DANRE Computationally mapped isoform of Segment polarity protein dishevelled homolog DVL-1 isoform X9 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "locus": {} }, { "isoform_ac": "A0AC58IM08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#A0AC58IM08-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREGEFPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASSHRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSED", "length": 557, "header": "tr|A0AC58IM08-1|A0AC58IM08_DANRE Computationally mapped isoform of Segment polarity protein dishevelled homolog DVL-1 isoform X10 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "locus": {} }, { "isoform_ac": "A0AC58IM20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0/entry#A0AC58IM20-1", "sequence": { "sequence": "MAETKIIYHIDEEETPYLVKLSVSPEKVTLADFKNVLNNRPVNSYKFFFKSMDQDFGVVKEEISDDNAKLPCFNGRVVAWLVLAEGTHSDGGSQCTESHKELLPPLERTGGIGDSRPPSFHANAVSSRDGLDTETGTESLQSQRRERERDRAHRRTREVPRVNGHPKSERLNRDSAVVYDSASVMSSELESSSFIDSDDDASRLSSSTGQSSLSRSTRIHKLKRRRPKDHKMNRSSSFSSITDSTMSLNIITVTLNMVLSVFVTEKYNFLGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNEVNFENMSNDDAVRILREIVSKPGPISLTVAKCWDPSPRSYFTIPRAEPVRPIDPAAWITHTTALSGPYPHYEFDDLPLSVSKTDMATIVKVMQLPDSGLEIRDRMWLKITIANAVIGADVVDWLFSRVEGFKDRRDARKYASSLLKHGYLRHTVNKITFSEQCYYTFGDLCQNMASLNLNEGSSGGGSDQDGLAPLPPPGTNPWPLGGQPYPYPGYPTPPPGFPPGYSDPCHSFHSGSAGSQQSEGSRSSGSNPSAGKGRRASPREKEHKAPCCGGSESELVTWVTRRGEKAPSQLSHQSHSRSAASQSQSAYSHGHTQCHLIPQHSLSFSYSHAPFIQPSHLSCAHSERSHGSSYGPPGLPPPYCLAHLAPKTAAGNSNSPPGAPPIREIGNVPPELTASRQSFQHAMGNPCEFFVDIM", "length": 734, "header": "tr|A0AC58IM20-1|A0AC58IM20_DANRE Computationally mapped isoform of Segment polarity protein dishevelled homolog DVL-1 isoform X4 OS=Danio rerio OX=7955 GN=dvl1a PE=3 SV=1 CANONICAL=A0A8M9PFK0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 536, "start_aa": "Thr", "end_pos": 536, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr536", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:569863", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569863", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0" } ], "pmid": "" }, { "name": "canonical Wnt signaling pathway", "id": "GO:0060070", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060070", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "frizzled binding", "id": "GO:0005109", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005109", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFK0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PFK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0" }, { "id": "PS50186", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50186" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DEP", "eco_id": "ECO_0000259", "start_pos": 413, "end_pos": 487, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PFK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0" }, { "id": "PS50841", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50841" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DIX", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 85, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PFK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFK0" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 262, "end_pos": 335, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 536 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 237, "end_pos": 239 }, { "start_pos": 323, "end_pos": 325 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z4C0-1", "uniprot_ac": "A0A8M6Z4C0", "uniprot_id": "A0A8M6Z4C0_DANRE", "mass": { "chemical_mass": 31851.0, "monoisotopic_mass": 31851.0 }, "refseq": { "ac": "XP_017208968", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208968" }, "gene_names": [ { "name": "LOC108181220", "type": "recommended", "evidence": [ { "id": "A0A8M6Z4C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4C0" } ] }, { "name": "LOC108181220", "type": "synonym", "evidence": [ { "id": "XP_017208968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208968" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M6Z4C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4C0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017208968", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208968" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017208968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208968" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4C0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4C0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108181220", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4C0", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z4C0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z4C0", "database": "AlphaFoldDB", "categories": [] }, { "id": "108181220", "url": "https://www.ncbi.nlm.nih.gov/gene/108181220", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108181220", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108181220", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z4C0", "url": "https://www.orthodb.org/?gene=A0A8M6Z4C0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_017208968", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208968", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4C0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4C0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MHLKGNYFRQRKKMFCSFLFNCLYLFCLVGVFADSDVVMSVMEGDSVTLESGVAEIKKEHVVKWQFGNKNKTIAQKKLSGNFSTSDVYMEFRDRLKLDHQTGSLTIMNTTTAHSGLYKPVISGYTKTKYSLNVYAHLPVPVITSKSLNSCSVLCSVVNMSAVSLSWYKGNRLFSRISVSDLSNSLHLDLKCLDDSYSCVVNISNTKQTTHLTNTELCQPCPGPSKCEQLNITELCQTHAVHVGGCESTEAVLRLVVTIVMGVAAAAAVVLLVNDIRSTRASMMKTGDLS", "length": 289, "header": "tr|A0A8M6Z4C0-1|A0A8M6Z4C0_DANRE Isoform 1 of Ig-like domain-containing protein OS=Danio rerio OX=7955 GN=LOC108181220 PE=4 SV=1 CANONICAL=A0A8M6Z4C0-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z4C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4C0/entry#A0A8M6Z4C0-1", "sequence": { "sequence": "MHLKGNYFRQRKKMFCSFLFNCLYLFCLVGVFADSDVVMSVMEGDSVTLESGVAEIKKEHVVKWQFGNKNKTIAQKKLSGNFSTSDVYMEFRDRLKLDHQTGSLTIMNTTTAHSGLYKPVISGYTKTKYSLNVYAHLPVPVITSKSLNSCSVLCSVVNMSAVSLSWYKGNRLFSRISVSDLSNSLHLDLKCLDDSYSCVVNISNTKQTTHLTNTELCQPCPGPSKCEQLNITELCQTHAVHVGGCESTEAVLRLVVTIVMGVAAAAAVVLLVNDIRSTRASMMKTGDLS", "length": 289, "header": "tr|A0A8M6Z4C0-1|A0A8M6Z4C0_DANRE Isoform 1 of Ig-like domain-containing protein OS=Danio rerio OX=7955 GN=LOC108181220 PE=4 SV=1 CANONICAL=A0A8M6Z4C0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108181220", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108181220", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z4C0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4C0" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 209, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 158, "end_pos": 160 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 70, "end_pos": 72 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9NYK6-1", "uniprot_ac": "A0A8M9NYK6", "uniprot_id": "A0A8M9NYK6_DANRE", "mass": { "chemical_mass": 162747.0, "monoisotopic_mass": 162747.0 }, "refseq": { "ac": "XP_021322057", "name": "protein turtle homolog B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322057" }, "gene_names": [ { "name": "igsf9ba", "type": "recommended", "evidence": [ { "id": "A0A8M9NYK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6" } ] }, { "name": "igsf9ba", "type": "synonym", "evidence": [ { "id": "XP_021322057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322057" } ] } ], "protein_names": [ { "name": "Protein turtle homolog B isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9NYK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6/entry#names_and_taxonomy" } ] }, { "name": "protein turtle homolog B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322057", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322057" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322057.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322057" } ] } ], "disease": [ { "disease_id": "DOID:1596", "recommended_name": { "id": "DOID:1596", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function." }, "synonyms": [ { "id": "DOID:1596", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1596", "name": "mental depression", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NYK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "igsf9ba", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-729", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-729", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000033845", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000033845", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "567389", "url": "https://www.ncbi.nlm.nih.gov/gene/567389", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567389", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567389", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RSTETWQ", "url": "https://omabrowser.org/oma/group/RSTETWQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9NYK6", "url": "https://www.orthodb.org/?gene=A0A8M9NYK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P772", "url": "https://www.orthodb.org/?gene=A0A8M9P772", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12231:SF240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12231:SF240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322057", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322057", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9NYK6", "url": 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"MIWYVATLIASVFSTRGTAAQGAHGVREEPQFVTARAGESVVLGCDVSHPLNGQQTPYVVEWFKFGVPIPFFINFRFYPPHVDPEYAGRASLHGKASLQIEQVRSEDQGWYECRVLMLEQQYDTFHNGSWVHLTVNAPPTFSDTPPQYVEAREGGSITLTCTAFGNPKPVVTWLREGDQLTSTRKYTVSDGSLTVQAITREDRGAYSCRAHSDQGEALHTTRLLVQGPPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYTWYWEEDNVYFKNDLKLRVRIFIDGTLIIYRVKPEDAGKYTCSPSNSLGISPSASAYLTVQYPARVVNMPPVIYVPRKLSGIIRCPVDANPPVTSVRWEKDGYPLRIEKYPGWSQMTDGSIRVAEVTEDSLGTYTCVPYNVLGTMGQSPPATLVLKDPPYFNVRPGGEYRQEAGRELVIPCAASGDPEIPTIQWRKVGKPSRSKHNLLPSGSLQFVSLSKEDHGEWECVATNVVTSITASTRLFVIGTSPHAPTNVHVSASTSSANVSWEPGYDGGFEQTFSVWYGPVKVKNDVGTHDWLSIPVPGSQMWLVVQGLEPKTAYQFSVLAQNKLGTGPFSEVVTVTTGGYPISTPEPLVLLTPPRCLTANRTQQGVLLTWLPPANHTSPIDRYVIEFRLGEKWEVLDDLIPATETEIIARDLIQDSWYEFRALAIMDDLVSESSNVVGVSSTDPFPPTEISDEGLAKPVVAGIVATICFLAAAILFSTLAACFVNKQHRRKLKRKRDPPLSITHTRKSIESPPPLTPLPGIEPYWEEPDRSSYRPPSTSPQLSSGKISPESIASSRPPSLASVGGHGLYVKKLPSPRKEKELSLYKKTKRAITSKKYSVSKHEAEVTTPIELISRGPDGRFVMDPNDIDSSLKPRRIEGFPFVEESDLYPEFRQSDEENDDPGPLPPVMATLRPQISPVSSSQESYMQPPAYSPRFQRPMEGMSISEGSRLQATGQSRVSHFHRVFPPGPFYGYIGSGAEVELHPPFYMPDVSPRSSAMSSSPSYPPEGPFRHPTIPEEREELRIHQYGASGHALPLVHSPPSSRSTEIWQPPDFPFLGQEGPRLALPPRHSSYLHRDLPEPPPYPSHSRTVSTTSQLPSSSAFLQLEAPRTHLSRSPGRFPPQGPSAKHITMQQAQTLGQLRHTAHGMGVPVLPYSGATTRMGSPSTLHSESSDGWRSEAQPWMSPRAARKMDLGLQQVVLQPSRLSPLTQTPPSSHAGSPDILVRPPPRPSILRSSRSQEMPESARHPASVSFSRRSLSSSPATSPTQGQSGQRPSLSYRAHMAFATAAASYPSQSPSPPAESSDAFGQMPSQRRTDEEMLPSEPSPGEHLGAVRVPAGSESFEALINYCINKAKKSSANKNNNSRFKKRTDMSTSQTQQPHASQASVQREHLSSPSKKKWKSTLRKHPCLHLSSLLRWLHPREDRKFLLASMDPVSSNYGSLL", "length": 1475, "header": "tr|A0A8M9NYK6-1|A0A8M9NYK6_DANRE Isoform 1 of Protein turtle homolog B isoform X1 OS=Danio rerio OX=7955 GN=igsf9ba PE=3 SV=2 CANONICAL=A0A8M9NYK6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9NYK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6/entry#A0A8M9NYK6-1", "sequence": { "sequence": "MIWYVATLIASVFSTRGTAAQGAHGVREEPQFVTARAGESVVLGCDVSHPLNGQQTPYVVEWFKFGVPIPFFINFRFYPPHVDPEYAGRASLHGKASLQIEQVRSEDQGWYECRVLMLEQQYDTFHNGSWVHLTVNAPPTFSDTPPQYVEAREGGSITLTCTAFGNPKPVVTWLREGDQLTSTRKYTVSDGSLTVQAITREDRGAYSCRAHSDQGEALHTTRLLVQGPPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYTWYWEEDNVYFKNDLKLRVRIFIDGTLIIYRVKPEDAGKYTCSPSNSLGISPSASAYLTVQYPARVVNMPPVIYVPRKLSGIIRCPVDANPPVTSVRWEKDGYPLRIEKYPGWSQMTDGSIRVAEVTEDSLGTYTCVPYNVLGTMGQSPPATLVLKDPPYFNVRPGGEYRQEAGRELVIPCAASGDPEIPTIQWRKVGKPSRSKHNLLPSGSLQFVSLSKEDHGEWECVATNVVTSITASTRLFVIGTSPHAPTNVHVSASTSSANVSWEPGYDGGFEQTFSVWYGPVKVKNDVGTHDWLSIPVPGSQMWLVVQGLEPKTAYQFSVLAQNKLGTGPFSEVVTVTTGGYPISTPEPLVLLTPPRCLTANRTQQGVLLTWLPPANHTSPIDRYVIEFRLGEKWEVLDDLIPATETEIIARDLIQDSWYEFRALAIMDDLVSESSNVVGVSSTDPFPPTEISDEGLAKPVVAGIVATICFLAAAILFSTLAACFVNKQHRRKLKRKRDPPLSITHTRKSIESPPPLTPLPGIEPYWEEPDRSSYRPPSTSPQLSSGKISPESIASSRPPSLASVGGHGLYVKKLPSPRKEKELSLYKKTKRAITSKKYSVSKHEAEVTTPIELISRGPDGRFVMDPNDIDSSLKPRRIEGFPFVEESDLYPEFRQSDEENDDPGPLPPVMATLRPQISPVSSSQESYMQPPAYSPRFQRPMEGMSISEGSRLQATGQSRVSHFHRVFPPGPFYGYIGSGAEVELHPPFYMPDVSPRSSAMSSSPSYPPEGPFRHPTIPEEREELRIHQYGASGHALPLVHSPPSSRSTEIWQPPDFPFLGQEGPRLALPPRHSSYLHRDLPEPPPYPSHSRTVSTTSQLPSSSAFLQLEAPRTHLSRSPGRFPPQGPSAKHITMQQAQTLGQLRHTAHGMGVPVLPYSGATTRMGSPSTLHSESSDGWRSEAQPWMSPRAARKMDLGLQQVVLQPSRLSPLTQTPPSSHAGSPDILVRPPPRPSILRSSRSQEMPESARHPASVSFSRRSLSSSPATSPTQGQSGQRPSLSYRAHMAFATAAASYPSQSPSPPAESSDAFGQMPSQRRTDEEMLPSEPSPGEHLGAVRVPAGSESFEALINYCINKAKKSSANKNNNSRFKKRTDMSTSQTQQPHASQASVQREHLSSPSKKKWKSTLRKHPCLHLSSLLRWLHPREDRKFLLASMDPVSSNYGSLL", "length": 1475, "header": "tr|A0A8M9NYK6-1|A0A8M9NYK6_DANRE Isoform 1 of Protein turtle homolog B isoform X1 OS=Danio rerio OX=7955 GN=igsf9ba PE=3 SV=2 CANONICAL=A0A8M9NYK6-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P772-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6/entry#A0A8M9P772-1", "sequence": { "sequence": "MIWYVATLIASVFSTRGTAAQGAHGVREEPQFVTARAGESVVLGCDVSHPLNGQQTPYVVEWFKFGVPIPFFINFRFYPPHVDPEYAGRASLHGKASLQIEQVRSEDQGWYECRVLMLEQQYDTFHNGSWVHLTVNAPPTFSDTPPQYVEAREGGSITLTCTAFGNPKPVVTWLREGDQLTSTRKYTVSDGSLTVQAITREDRGAYSCRAHSDQGEALHTTRLLVQGPPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYTWYWEEDNVYFKNDLKLRVRIFIDGTLIIYRVKPEDAGKYTCSPSNSLGISPSASAYLTVQYPARVVNMPPVIYVPRKLSGIIRCPVDANPPVTSVRWEKDGYPLRIEKYPGWSQMTDGSIRVAEVTEDSLGTYTCVPYNVLGTMGQSPPATLVLKDPPYFNVRPGGEYRQEAGRELVIPCAASGDPEIPTIQWRKVGKPSRSKHNLLPSGSLQFVSLSKEDHGEWECVATNVVTSITASTRLFVIGTSPHAPTNVHVSASTSSANVSWEPGYDGGFEQTFSVWYGPVKVKNDVGTHDWLSIPVPGSQMWLVVQGLEPKTAYQFSVLAQNKLGTGPFSEVVTVTTGGYPISTPEPLVLLTPPRCLTANRTQQGVLLTWLPPANHTSPIDRYVIEFRLGEKWEVLDDLIPATETEIIARDLIQDSWYEFRALAIMDDLVSESSNVVGVSSTEISDEGLAKPVVAGIVATICFLAAAILFSTLAACFVNKQHRRKLKRKRDPPLSITHTRKSIESPPPLTPLPGIEPYWEEPDRSSYRPPSTSPQLSSGKISPESIASSRPPSLASVGGHGLYVKKLPSPRKEKELSLYKKTKRAITSKKYSVSKHEAEVTTPIELISRGPDGRFVMDPNDIDSSLKPRRIEGFPFVEESDLYPEFRQSDEENDDPGPLPPVMATLRPQISPVSSSQESYMQPPAYSPRFQRPMEGMSISEGSRLQATGQSRVSHFHRVFPPGPFYGYIGSGAEVELHPPFYMPDVSPRSSAMSSSPSYPPEGPFRHPTIPEEREELRIHQYGASGHALPLVHSPPSSRSTEIWQPPDFPFLGQEGPRLALPPRHSSYLHRDLPEPPPYPSHSRTVSTTSQLPSSSAFLQLEAPRTHLSRSPGRFPPQGPSAKHITMQQAQTLGQLRHTAHGMGVPVLPYSGATTRMGSPSTLHSESSDGWRSEAQPWMSPRAARKMDLGLQQVVLQPSRLSPLTQTPPSSHAGSPDILVRPPPRPSILRSSRSQEMPESARHPASVSFSRRSLSSSPATSPTQGQSGQRPSLSYRAHMAFATAAASYPSQSPSPPAESSDAFGQMPSQRRTDEEMLPSEPSPGEHLGAVRVPAGSESFEALINYCINKAKKSSANKNNNSRFKKRTDMSTSQTQQPHASQASVQREHLSSPSKKKWKSTLRKHPCLHLSSLLRWLHPREDRKFLLASMDPVSSNYGSLL", "length": 1469, "header": "tr|A0A8M9P772-1|A0A8M9P772_DANRE Computationally mapped isoform of Protein turtle homolog B isoform X2 OS=Danio rerio OX=7955 GN=igsf9ba PE=3 SV=2 CANONICAL=A0A8M9NYK6-1" }, "locus": {} }, { "isoform_ac": "A0AC58HCH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6/entry#A0AC58HCH4-1", "sequence": { "sequence": "MIWYVATLIASVFSTRGTAAQGAHGVREEPQFVTARAGESVVLGCDVSHPLNGQQTPYVVEWFKFGVPIPFFINFRFYPPHVDPEYAGRASLHGKASLQIEQVRSEDQGWYECRVLMLEQQYDTFHNGSWVHLTVNAPPTFSDTPPQYVEAREGGSITLTCTAFGNPKPVVTWLREGDQLTSTRKYTVSDGSLTVQAITREDRGAYSCRAHSDQGEALHTTRLLVQGPPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYTWYWEEDNVYFKNDLKLRVRIFIDGTLIIYRVKPEDAGKYTCSPSNSLGISPSASAYLTVQYPARVVNMPPVIYVPRKLSGIIRCPVDANPPVTSVRWEKDGYPLRIEKYPGWSQMTDGSIRVAEVTEDSLGTYTCVPYNVLGTMGQSPPATLVLKDPPYFNVRPGGEYRQEAGRELVIPCAASGDPEIPTIQWRKVGKPSRSKHNLLPSGSLQFVSLSKEDHGEWECVATNVVTSITASTRLFVIGTSPHAPTNVHVSASTSSANVSWEPGYDGGFEQTFSVWYGPVKVKNDVGTHDWLSIPVPGSQMWLVVQGLEPKTAYQFSVLAQNKLGTGPFSEVVTVTTGGYPISTPEPLVLLTPPRCLTANRTQQGVLLTWLPPANHTSPIDRYVIEFRLGEKWEVLDDLIPATETEIIARDLIQDSWYEFRALAIMDDLVSESSNVVGVSSTEISDEGLAKPVVAGIVATICFLAAAILFSTLAACFVNKQHRRKLKRKRDPPLSITHTRKSIESPLSSGKISPESIASSRPPSLASVGGHGLYVKKLPSPRKEKELSLYKKTKRAITSKKYSVSKHEAEVTTPIELISRGPDGRFVMDPNDIDSSLKPRRIEGFPFVEESDLYPEFRQSDEENDDPGPLPPVMATLRPQISPVSSSQESYMQPPAYSPRFQRPMEGMSISEGSRLQATGQSRVSHFHRVFPPGPFYGYIGSGAEVELHPPFYMPDVSPRSSAMSSSPSYPPEGPFRHPTIPEEREELRIHQYGASGHALPLVHSPPSSRSTEIWQPPDFPFLGQEGPRLALPPRHSSYLHRDLPEPPPYPSHSRTVSTTSQLPSSSAFLQLEAPRTHLSRSPGRFPPQGPSAKHITMQQAQTLGQLRHTAHGMGVPVLPYSGATTRMGSPSTLHSESSDGWRSEAQPWMSPRAARKMDLGLQQVVLQPSRLSPLTQTPPSSHAGSPDILVRPPPRPSILRSSRSQEMPESARHPASVSFSRRSLSSSPATSPTQGQSGQRPSLSYRAHMAFATAAASYPSQSPSPPAESSDAFGQMPSQRRTDEEMLPSEPSPGEHLGAVRVPAGSESFEALINYCINKAKKSSANKNNNSRFKKRTDMSTSQTQQPHASQASVQREHLSSPSKKKWKSTLRKHPCLHLSSLLRWLHPREDRKFLLASMDPVSSNYGSLL", "length": 1440, "header": "tr|A0AC58HCH4-1|A0AC58HCH4_DANRE Computationally mapped isoform of Protein turtle homolog B isoform X4 OS=Danio rerio OX=7955 GN=igsf9ba PE=3 SV=1 CANONICAL=A0A8M9NYK6-1" }, "locus": {} }, { "isoform_ac": "A0AC58HCH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6/entry#A0AC58HCH6-1", "sequence": { "sequence": "MCCHQCRNKHHCQHTPFCNRKVKNDVGTHDWLSIPVPGSQMWLVVQGLEPKTAYQFSVLAQNKLGTGPFSEVVTVTTGGYPISTPEPLVLLTPPRCLTANRTQQGVLLTWLPPANHTSPIDRYVIEFRLGEKWEVLDDLIPATETEIIARDLIQDSWYEFRALAIMDDLVSESSNVVGVSSTDPFPPTEISDEGLAKPVVAGIVATICFLAAAILFSTLAACFVNKQHRRKLKRKRDPPLSITHTRKSIESPPPLTPLPGIEPYWEEPDRSSYRPPSTSPQLSSGKISPESIASSRPPSLASVGGHGLYVKKLPSPRKEKELSLYKKTKRAITSKKYSVSKHEAEVTTPIELISRGPDGRFVMDPNDIDSSLKPRRIEGFPFVEESDLYPEFRQSDEENDDPGPLPPVMATLRPQISPVSSSQESYMQPPAYSPRFQRPMEGMSISEGSRLQATGQSRVSHFHRVFPPGPFYGYIGSGAEVELHPPFYMPDVSPRSSAMSSSPSYPPEGPFRHPTIPEEREELRIHQYGASGHALPLVHSPPSSRSTEIWQPPDFPFLGQEGPRLALPPRHSSYLHRDLPEPPPYPSHSRTVSTTSQLPSSSAFLQLEAPRTHLSRSPGRFPPQGPSAKHITMQQAQTLGQLRHTAHGMGVPVLPYSGATTRMGSPSTLHSESSDGWRSEAQPWMSPRAARKMDLGLQQVVLQPSRLSPLTQTPPSSHAGSPDILVRPPPRPSILRSSRSQEMPESARHPASVSFSRRSLSSSPATSPTQGQSGQRPSLSYRAHMAFATAAASYPSQSPSPPAESSDAFGQMPSQRRTDEEMLPSEPSPGEHLGAVRVPAGSESFEALINYCINKAKKSSANKNNNSRFKKRTDMSTSQTQQPHASQASVQREHLSSPSKKKWKSTLRKHPCLHLSSLLRWLHPREDRKFLLASMDPVSSNYGSLL", "length": 946, "header": "tr|A0AC58HCH6-1|A0AC58HCH6_DANRE Computationally mapped isoform of Protein turtle homolog B isoform X5 OS=Danio rerio OX=7955 GN=igsf9ba PE=4 SV=1 CANONICAL=A0A8M9NYK6-1" }, "locus": {} }, { "isoform_ac": "A0AC58HCK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6/entry#A0AC58HCK8-1", "sequence": { "sequence": "MCCHQCRNKHHCQHTPFCNRKVKNDVGTHDWLSIPVPGSQMWLVVQGLEPKTAYQFSVLAQNKLGTGPFSEVVTVTTGGYPISTPEPLVLLTPPRCLTANRTQQGVLLTWLPPANHTSPIDRYVIEFRLGEKWEVLDDLIPATETEIIARDLIQDSWYEFRALAIMDDLVSESSNVVGVSSTDPFPPTEISDEGLAKPVVAGIVATICFLAAAILFSTLAACFVNKQHRRKLKRKRDPPLSITHTRKSIESPLSSGKISPESIASSRPPSLASVGGHGLYVKKLPSPRKEKELSLYKKTKRAITSKKYSVSKHEAEVTTPIELISRGPDGRFVMDPNDIDSSLKPRRIEGFPFVEESDLYPEFRQSDEENDDPGPLPPVMATLRPQISPVSSSQESYMQPPAYSPRFQRPMEGMSISEGSRLQATGQSRVSHFHRVFPPGPFYGYIGSGAEVELHPPFYMPDVSPRSSAMSSSPSYPPEGPFRHPTIPEEREELRIHQYGASGHALPLVHSPPSSRSTEIWQPPDFPFLGQEGPRLALPPRHSSYLHRDLPEPPPYPSHSRTVSTTSQLPSSSAFLQLEAPRTHLSRSPGRFPPQGPSAKHITMQQAQTLGQLRHTAHGMGVPVLPYSGATTRMGSPSTLHSESSDGWRSEAQPWMSPRAARKMDLGLQQVVLQPSRLSPLTQTPPSSHAGSPDILVRPPPRPSILRSSRSQEMPESARHPASVSFSRRSLSSSPATSPTQGQSGQRPSLSYRAHMAFATAAASYPSQSPSPPAESSDAFGQMPSQRRTDEEMLPSEPSPGEHLGAVRVPAGSESFEALINYCINKAKKSSANKNNNSRFKKRTDMSTSQTQQPHASQASVQREHLSSPSKKKWKSTLRKHPCLHLSSLLRWLHPREDRKFLLASMDPVSSNYGSLL", "length": 917, "header": "tr|A0AC58HCK8-1|A0AC58HCK8_DANRE Computationally mapped isoform of Protein turtle homolog B isoform X6 OS=Danio rerio OX=7955 GN=igsf9ba PE=4 SV=1 CANONICAL=A0A8M9NYK6-1" }, "locus": {} }, { "isoform_ac": "A0ACD6B6L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6/entry#A0ACD6B6L6-1", "sequence": { "sequence": "MIWYVATLIASVFSTRGTAAQGAHGVREEPQFVTARAGESVVLGCDVSHPLNGQQTPYVVEWFKFGVPIPFFINFRFYPPHVDPEYAGRASLHGKASLQIEQVRSEDQGWYECRVLMLEQQYDTFHNGSWVHLTVNAPPTFSDTPPQYVEAREGGSITLTCTAFGNPKPVVTWLREGDQLTSTRKYTVSDGSLTVQAITREDRGAYSCRAHSDQGEALHTTRLLVQGPPYIVTPPENITVNISQNAQFTCQAEAYPGNLTYTWYWEEDNVYFKNDLKLRVRIFIDGTLIIYRVKPEDAGKYTCSPSNSLGISPSASAYLTVQYPARVVNMPPVIYVPRKLSGIIRCPVDANPPVTSVRWEKDGYPLRIEKYPGWSQMTDGSIRVAEVTEDSLGTYTCVPYNVLGTMGQSPPATLVLKDPPYFNVRPGGEYRQEAGRELVIPCAASGDPEIPTIQWRKVGKPSRSKHNLLPSGSLQFVSLSKEDHGEWECVATNVVTSITASTRLFVIGTSPHAPTNVHVSASTSSANVSWEPGYDGGFEQTFSVWYGPVKVKNDVGTHDWLSIPVPGSQMWLVVQGLEPKTAYQFSVLAQNKLGTGPFSEVVTVTTGGYPISTPEPLVLLTPPRCLTANRTQQGVLLTWLPPANHTSPIDRYVIEFRLGEKWEVLDDLIPATETEIIARDLIQDSWYEFRALAIMDDLVSESSNVVGVSSTDPFPPTEISDEGLAKPVVAGIVATICFLAAAILFSTLAACFVNKQHRRKLKRKRDPPLSITHTRKSIESPLSSGKISPESIASSRPPSLASVGGHGLYVKKLPSPRKEKELSLYKKTKRAITSKKYSVSKHEAEVTTPIELISRGPDGRFVMDPNDIDSSLKPRRIEGFPFVEESDLYPEFRQSDEENDDPGPLPPVMATLRPQISPVSSSQESYMQPPAYSPRFQRPMEGMSISEGSRLQATGQSRVSHFHRVFPPGPFYGYIGSGAEVELHPPFYMPDVSPRSSAMSSSPSYPPEGPFRHPTIPEEREELRIHQYGASGHALPLVHSPPSSRSTEIWQPPDFPFLGQEGPRLALPPRHSSYLHRDLPEPPPYPSHSRTVSTTSQLPSSSAFLQLEAPRTHLSRSPGRFPPQGPSAKHITMQQAQTLGQLRHTAHGMGVPVLPYSGATTRMGSPSTLHSESSDGWRSEAQPWMSPRAARKMDLGLQQVVLQPSRLSPLTQTPPSSHAGSPDILVRPPPRPSILRSSRSQEMPESARHPASVSFSRRSLSSSPATSPTQGQSGQRPSLSYRAHMAFATAAASYPSQSPSPPAESSDAFGQMPSQRRTDEEMLPSEPSPGEHLGAVRVPAGSESFEALINYCINKAKKSSANKNNNSRFKKRTDMSTSQTQQPHASQASVQREHLSSPSKKKWKSTLRKHPCLHLSSLLRWLHPREDRKFLLASMDPVSSNYGSLL", "length": 1446, "header": "tr|A0ACD6B6L6-1|A0ACD6B6L6_DANRE Computationally mapped isoform of Protein turtle homolog B isoform X3 OS=Danio rerio OX=7955 GN=igsf9ba PE=3 SV=1 CANONICAL=A0A8M9NYK6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:567389", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567389", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7TDD3-1", "protein_name": "Uncharacterized protein igsf9b isoform X1", "gene_name": "igsf9b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVQKKLWLLNVSVAVALSLLRLTLSTEPVVQGRVGGFAELGCSLTPPSEGATTPNLFPLHVVEWVRLGYNVPILIKFGSYTPRVHPNYKGRVSLSRGASLMVEKLTLEDEGWFECRILLLDRTSDEFQNGTWNFLSITAPPVFIKTPPPFLEVLLGESLTLHCDAHGNPKPTIIWRKYLSAAEKQEEIQVLNETLSLSKVTRETAGIYKCHVSNSEGNLTHSTQLQVKGPPIIIIAPEDTTMNMSQDAVLQCQAEAYPSNLTYEWWKQGQNVYHIEILKSRVKILVDGTLLISALIPDDSGNYTCRPTNGLMTPPAASAYLTVKHPARVVRMPRETYLPMGMGGKIPCPVQAEPPMLYVNWTKDGASLNLEQYPGWMVNSEGSVFITAANDDAVGMYTCTAYNSYGTMGQSEPTKVILKDPPSFRVSPRAEYLQEVGRDLVIPCQSQGDPSPNITWIKVGPAPRSPFTVLSNGSLFLRPLSKDHQGTWECLASNRVATVSVATTILVLGTSPHAVTSVSVDPGIGQANVSWEAGFDGGYTQRFTVWVKPTVRGKHEWASIPVPTSKTSLLVTSLQPATSYQFSVLAQNKLGSGPFSEIVTIKTLAPPTESPTVLTTMAVLSPPTLLSANRTSLGVLLQWVPPLEESLTSFALQAKRGKGEWVTIDREIAVNMTELIVQGLVKDSKYELRLLSCQDKLVSVPSDSVLISTEGMEMYPAAPSLLAFVPEPLLAGVIGGVCFLFVAIILSLVTACVMNSKRRQRRQKKRDDIPSAFQKSSAPQANSPSDSPDSLLKLKLCPPLNFFPNSSSSDRSDRSSFDKASRSEYQDQKKQLLSSSSPPPHYTQFESHFGGTPSPTPAIESISRSPDGRFIIQPDLENFKKNLKKEFPQSPSRGSGRGSSNGSFKESNQSNSARSETNAQTEMPSALTVDHPHLERPPHSPGRVRAMARNFSRHGCFYSDDEHGGSEALLERASFYSDCSEKKASDSLKKYRGAIHREEIFPSLTRRTRERDRMLQQAHYQPINGDSQLTEPSTMITQLDGERERDNLSKCLKLAKEREQMEKELEHYTASRRVQAHEREQRRAKSASPLRKWTGVESQDPIWKPQDIQLRQKSRPSSLAQHVSDNRRGCYFGNTSSPMERHPSSSSSYIQWDISPVTSPTSLVPVQSLSEGNTPHSLYPNMRQQAIPNVEGSSATGISHSPATQYTSLSIFTPHRESSPSRSSLHGAQARYSESQLEEELPNRTLVEESWLAERKIEKESPPFRSKSPAHLSPQPSELHQVLEGADRDANSHYLDPRSQDVTDKEEEGIVQKDRLLSRNPSGCSTLPYDHKRGAKEKVIDDSLSILPYNEQEKEGIRARSRKSDKCVLTESPSRISPLTLLENEAESDQSNFSRMSESMKVKLASQPARMSPLQTSTILEYLSLPGFIEMSVDDPVEVTEPSESVEPNVELESGTMLRVEPDVVPKSWEKHSQDLSGTNGVVHDHGTQNVPMEKPKPEDISEPLPQLEARDRCVKSGTSDKSNKRFPPLKEKNKSSEPLLSQSSGSQREQFIQHGPAQTLINTAKSMAAIVSKCPDFISQQYQRPQIHSDSTNMISSRINQAPVPFMKKSVSIGPCRTLSGAGQPRPFLRKSISLGSRYEHSELPRPYFSETCYRDQFPNPDIRLKSYSLGRTPSHYYPISGPSWRGSVPYQPPHSYSLERHHIERSGMTPPYQTTFVPNPSRQMEPSLPSRRESDPRRQAAVFPDSSRWPLSYQETLRSVQHKYVPQDPPRPFGPNRSLARVDYMHPAEPRRCPPRPFLPRGYSWPSPHHPSFPLREHDFPRELDKGMGAVRGCAETERDGGRASYASQSSGRGSVGPYGHLRQSLSITPTLLSSPETTEESERHRADKDTRERRSKRRNTSVDESYEWDAVEYSMDHDVLEAMKVERPHAAFGRGRGFRPERPRSTAGLQDLQSKRLYSVSPPLVSQPPQHRYSRSLSEARFNALRQEFQEYRRAQESCTQDPCIPHDPDSDSSSALL", "length": 2021 }, "evidence": [ { "id": "FB:FBgn0010473", "url": "https://alliancegenome.org/gene/FB:FBgn0010473#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TAW7-1", "protein_name": "Protein turtle homolog B isoform X1", "gene_name": "igsf9bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIWYVATLIASVFSTRGTAAQGAHGVREEPQFVTSRAGETVILGCDVVHPLNGQPYVVEWFKFGVPIPFFINFRFYPPHVDPEYAGRASLHGKSSLRIERVRSEDQGWYECKVLMLEQQYHTFHNGSWVHLTVNAPPTFTDTPPQYVEAKEGGSITLSCTAFGNPKPSVSWLREGNPVQDSTKYKVSDGSLTLVSISREDRGAYTCRAYSEQGEAVHTTRLLVQGPPFIVSPPENITVNISQDAFFTCQAEAYPGNLTYTWFWEEDNVFFKNDLKRRVSILIDGSLIISQVKPEDAGKYTCSPSNSLGRPPSASAYLTVHYPARVINMPPVIYVAIGLPGYIRCPVDANPPVTSVKWKKDGLPLRIEKYPGWSQMEDGSIRVSEVTEDSLGTYTCVPYNSLGTMGPSPPAPLVLKDPPKFLVVPGGEYRQEAGRELVIPCEAEGDPFPNITWRKKVGKPSRSKHNVLPRGSLQFKSLSKEDHGEWECVASNVATSITASTHLLVIGTSPHAPAKVHVTVSTTSANVSWDSSYDGGFEQTFSVWYGHVVKREQLGPHDWLSMPVPSGQHWLLVQGLEPETAYQFSVLAQNKLGTGPFSEVVTVNTLVFPISTPEPLVLLTPPRCLTANRTQQGVLLTWIPPANHTSPIDHYIMDFRLGERWDVLDDAIPAGETEILARDLIQEAWYEFRVMAVMEDLVSEPSNVVGVSSTDYFPPPEVPDEGLARPVVAGIVATICFLAAAILFSTLAACFVNKQRRRKLKRRRDPPLSITHCRKSVETPSSSGKISPESIRSIGPPSESSEDGLRAKKFPQSPAKEELSLYKKTKRAIISKKYSVSKHEAEATTPIELISRGPDGRFVMDPTDMETPVKARRIEGFPFVEESDLYPEFRQSDEENDDPGPMPPVMATLRPHQISPISSSQESYLQPPAYSPRFQRPMEGMTIMETSRLQATGQIRGAPHFRAFTHGQFYSYLGSPGEPEPPPPFYMPDTSPLSSVMSSPPYHLEGPFGHPTIPEEIGEGEIQHYAVSGYTLPLAHPSTSRSPDIWQRPDFTFATIEGPHFIFPPPHPLHLHPEPPLPPPLVLPPSALQPSTLQVSPYPGILQLEAPKSRPGKSPSKVKPQGLPAKRLPMQEAQSLGQLRHTSHGMGVPVLPYPDPVSHMVGPSSFGSLDTRWYELTPRLSPRQPRRMEPSMVVLQPSRLSPLTQSPISSHEGSPEIVVRPRPRPSMIQPPIPPEMSEITLQPPSSASFSRRSSPSSSPAQGQGSRRASPSYRSHMAFATSAASYPSQSPSPPVESSNIFGQMPTQRRTEEEILPSEPSPPQLSASGYIHYVAILRKRRGAPSGSAGSERIEALRYQRVKKAKKVGINNNNSKARRKTGVPPSQTQQPHTSQVLQPEEALYLRKKKKKLTRQDPYARFSALLYRRPTREDQKAILASMDTADPDHATLL", "length": 1448 }, "evidence": [ { "id": "HGNC:32326", "url": "https://alliancegenome.org/gene/HGNC:32326#orthology", "database": "AGR" }, { "id": "MGI:2685354", "url": "https://alliancegenome.org/gene/MGI:2685354#orthology", "database": "AGR" }, { "id": "RGD:1564717", "url": "https://alliancegenome.org/gene/RGD:1564717#orthology", "database": "AGR" }, { "id": "FB:FBgn0010473", "url": "https://alliancegenome.org/gene/FB:FBgn0010473#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ACD6B6E7-1", "protein_name": "Protein turtle homolog B", "gene_name": "igsf9a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRLKNLPLLEVIVAVLCLFNDTSAAEEHVRAKKDSSAVLPCSLPAPQKDSSASQYVIEWVRQGFDTPIFMQLGVHPRVHPDYDGRVSLFGGTSLQMSGLQLEDEGWYECRILPLDQTTEEAGSSGSWTRLFVTAPPVLTETSPPEVEVFVGRSLTLKCAAQGNPRPTITWSKDGAPIKPQHKVKMVNGSVSFHAVSREAAGQYQCYSSNSEGNATHVTRLKIIGPPVIIIPPSDTVLNMSQDAKLKCQAEADPPNMTYVWQRQGVDIYHIDSLKSRIKVIVDGTLLISRLAPEDSGNYTCMPTNGLPVSPSASAVLTVQHPAQVIQMPKLTFLPTGMRGAIVCPVRAEPPLSHIDWIKDGKPLDLGMYPGWTLASDGSIVIATVNDDAAGVYICTPYNSFGTTGQSEPTTVILQDPPSFKVSPRNEYRQDVGTMLVIPCQMVGNPAPKVNWRKIGAATRSLFTLAGNGSLILHPLSKDHQGEWECSSSNRVATVSIKTMVLVLGTSPHAVSSVSVIPGTNQANVSWVAGFDGGYTQTFTVWYKQVSAGRTEEKQEWLSFSDLSTENSLLVTNLLPATEYQFSVMAQNKIGTGPFSEIITVTTLDALPVVAKLEPPTNLSVNKSSEGFLLLWSAPHSKSPPIDSFVVQSRLEGGEWDNLKEDISPAESKIFLPGLCKDCKYELRLLSQHGDQLSMPSPSISVSTFGMNMRPASSRLLDFPNHIMAGVMGGVGLLCLVLVLTLAIVCFISYKRSRRRRQNIKDLPPAMDKNASVNIPDDTLKQRLLPAHPLSTSSSASNHSSLDKFSHSDFHDLRQHHLPQANPPSHHSLPESHLQLSSLAPVSSVEFIHRGPDGRFVVHPGEGDSNFSSQIKRNPNQNSHQASDGSRSFRIQKSQSLRSYMDEQRRPPFVLSVDLPPFGSNIPSSSRTRAMVKHLSLNGHYMPILEKEIMDVPDQTSLSSDCSDSYLYAHSESTLGQKSPKRDTNHSTASTLVLQMEHEREQGNLSRCLTLAREREELERELRKYTVDLNSSSHEQTDDEYGNLWKTQEASTPQVKYQTMRQSILSENTGMFKRRAASCIPWEERHKISSANLLPLHKSYEKDIKYRQNQGYNSVQRSRYQRSRSLDREEHRKSHTWDQRRSKTPVESSRYCVMDELIYKLENPQTCEGPRARMTSSRSQHYFDPCIYPSPGDQQWRTVQRSNREIHPVGDYSEMSVDGPDFESQHANSRSTVRSEHSYETLDYDRPRLSELEMDRLVKPGHVSSRKDKKLNNWSSKTESPMNVSERMPQRTNSIGSKIRDQHQSTHSLDSKLYKDQFLTPDAWIDSLTLPQDCTMSPLVSRPNSVANKPKSSPNLQDHSFVPSGSQSHVPQRRASKSPNGFTNDQHSQRNLMSERNAHTALPPGGSSLPRAYYPSLSTLPSERRNQSHQAGREEEDMDGQDMDVEINIYRKGSETEGSYRSYGSQSSGRGSMDAPNSRQFSLSPPLTSSPETTEDSDRDEAALLDPEQNGRRDSVDESYEWEPAYVPMRPVVSMNKTGLQKEFKGSQRKQSSITKDDDSSNLDQKQKGLYPAAGLKGSVPLFEVPCVPPSQCQQESLLTRDIQKSFTSFSDPEPDTVLF", "length": 1619 }, "evidence": [ { "id": "FB:FBgn0010473", "url": "https://alliancegenome.org/gene/FB:FBgn0010473#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZB51-1", "protein_name": "Protein turtle homolog B", "gene_name": "Igsf9b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIWYVATLIASVISTRGLVAQVAHGLREEPEFVTARAGEGVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEYAGRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLSASGKYQVSDGSLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRKVGKPSRSKHNALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVHVSMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSLSVPLGPSWLLVDSLEPETAYQFSVLAQNRLGTSAFSEVVTVNTLAFPVTTPEPLVLVTPPRCLTANRTQQGVLLSWLPPANHSFPIDRYIMEFRVGERWEMLDDAIPGTDGEFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSSTDIFPQPDLTDDGLARPVLAGIVATICFLAAAILFSTLAACFVNKQRKRKLKRKKDPPLSITHCRKSLESPLSSGKVSPESIRTLRAPSESSDDQGQPAAKRMLSPTREKELSLYKKTKRAISSRKYSVAKAEAEAEATTPIELISRGPDGRFVMGPSEMEPSVKGRRIEGFPFAEETDMYPEFRQSDEENEDPLVPTSVAALKPQLTPMSSSQDSYLPPPAYSPRFQPRGLEGPSGLGGRLQATGQARPPAPRPFQHGQYYGYLSSSSPGEVEPPPFYMPEVGSPLSSVMSSPPLHTEGPFGHPTIPEENGENASNSTLPLTQTPTGGRSPEPWGRPEFPFGGLETPAMMFPHQLHPCDVAESLQPKPCLPRGLPPAPLQVPAAYPGMLSLEAPKGWVGKSPGRGPIPAPPATKWQERPMQPLVSQGQLRHTSQGMGIPVLPYPEPAEPGGHGGPSTFGLDTRWYEPQPRPRPSPRQARRAEPSLHQVVLQPSRLSPLTQSPLSSRTGSPELAARARPRPGLLQQAEMSEITLQPPAAVSFSRKSTPSSTGSPSQSSRSGSPSYRPTMGFTTLATGYPSPPPGPAPPAPGDNLDVFGQTPSPRRMGEEPLRPEPPTTLPTSG", "length": 1328 }, "evidence": [ { "id": "HGNC:32326", "url": "https://alliancegenome.org/gene/HGNC:32326#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-729", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-729#orthology", "database": "AGR" }, { "id": "MGI:2685354", "url": "https://alliancegenome.org/gene/MGI:2685354#orthology", "database": "AGR" }, { "id": "RGD:1564717", "url": "https://alliancegenome.org/gene/RGD:1564717#orthology", "database": "AGR" }, { "id": "FB:FBgn0010473", "url": "https://alliancegenome.org/gene/FB:FBgn0010473#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PZ19-1", "protein_name": "Protein turtle homolog B", "gene_name": "Igsf9b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIWYVATLIASVISTRGLVAQGAHGLREEPEFVTARAGEGVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEYAGRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASAKYQVSDGSLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDAGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRKVGKPSRSKHNALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVHVSMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSLSVPPGPSWLLVDSLEPETAYQFSVLAQNRLGTSAFSEVVTVNTLAFPVTTPEPLVLVTPPRCLTANRTQQGVLLSWLPPANHSFPIDRYIMEFRVGERWEMLDDAIPGTDGDFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSSTDIFPQPDLTDDGLARPVLAGIVATICFLAAAILFSTLAACFVNKQRKRKLKRKKDPPLSITHCRKSLESPLSSGKVSPESIRTLRAPSESSDDQGQPAAKRMLSPTREKELSLYKKTKRAISSRKYSVAKAEAEAEATTPIELISRGPDGRFVMGPSEMEPSVKGRRIEGFPFAEETDMYPEFRQSDEENEDPLVPTSVAALKPQLTPMSSSQDSYLPPPAYSPRFQPRGLEGPSGLGGRLQATGQARPPAPRPFQHGQYYGYLSSSSPGEVEPPPFYMPEVGSPLSSVMSSPPLHTEGPFGHPTIPEENGENASNSTLPLTQTPTGGRSPEPWGRPEFPFGGLETPAMMFPHQLHPCDVAESLQPKACLPRGLPPAPLQVPAAYPGMLSLEAPKGWVGKSPGRGPIPAPPATKWQERPMQPLVSQGQLRHTSQGMGIPVLPYPEPAEPGGHGGPSTFGLDTRWYEPQPRPRPSPRQARRAEPSLHQVVLQPSRLSPLTQSPLSSRTGSPELAARARPRPGLLQQAEMSEITLQPPAAVSFSRKSTPSSTGSPSQSSRSGSPSYRPTMGFTTLATGYPSPPPGPAPPAPGDTLDVFGQTPSPRRMGEEPLRPEPPTTLPTSG", "length": 1328 }, "evidence": [ { "id": "HGNC:32326", "url": "https://alliancegenome.org/gene/HGNC:32326#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-729", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-729#orthology", "database": "AGR" }, { "id": "MGI:2685354", "url": "https://alliancegenome.org/gene/MGI:2685354#orthology", "database": "AGR" }, { "id": "RGD:1564717", "url": "https://alliancegenome.org/gene/RGD:1564717#orthology", "database": "AGR" }, { "id": "FB:FBgn0010473", "url": "https://alliancegenome.org/gene/FB:FBgn0010473#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0C5H6-1", "protein_name": "Protein turtle homolog A", "gene_name": "Igsf9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIWCLRLTILSLILSQGADGRRKPEVVSVVGRAGESAVLGCDLLPPAGRPPLHVIEWLRFGFLLPIFIQFGLYSPRIDPDYVGRVRLQTGASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLTVNSPPQFQETPPLVLEVKELEAVTLRCVALGSPQPYVTWKFRGQDLGKGQGQVQVRNGTLWIRRVERGSAGDYTCQASSTEGSVTHTTQLLVLGPPVIVVPPNNNTVNASQDVSLACRAEAYPANLTYSWFQDRINVFHISRLQSRVRILVDGSLWLQATQPDDAGHYTCVPSNGFPHPPSASAYLTVLYPAQVTVMPPETPLPIGMRGVIRCPVRANPPLLFVTWTKDGQALQLDKFPGWSLGPEGSLVIALGNEDALGEYSCTPYNSLGTAGSSPVTRVLLKAPPAFIDQPKEEYFQEVGRDLLIPCSARGDPPPIVSWAKVGRGLQGQAQVDSNNSLILRPLTKEAHGRWECSARNAVAHVTISTNVYVLGTSPHVVTNVSVVPLPKGANVSWEPGFDGGYLQRFSVWYTPLAKRPDRAHHDWVSLAVPMGATHLLVPGLQAYTQYQFSVLAQNKLGSGPFSEIVLSIPEGLPTTPAVPRLPPTEMPPPLSPPRGLVAVRTPRGVLLHWDPPELIPERLDGYILEGRQGSQGWEILDQGVAGTEIQLLVPGLIKDVLYEFRLVAFADSYVSDPSNIANISTSGLEVYPSRTQLPGLLPQPVLAGVVGGVCFLGVAVLVSILAACLMNRRRAARRHRKRLRQDPPLIFSPRGRSGPHSAPGSDSPDSVTKFKLQGSPVPSLRQSLLWGEPARPPSPHPDSPLGRGPLPLEPICRGPDGRFVMGPTVAPPQEKLCLERSEPRTSAKRLAQSLDCSSSSPSGVPQPLCITDISPVGQPPAAMPSPLPGPGPLLQYLSLPFFREMNVDGDWPPLEEPTPASPPDFMGSHPCPTSSFLPPPDSPPTNLRAVLPGTLMGVGVSSEPPYTALADWTLRERVLPGLLSAAPRGSLTSQSSGRGSASFLRPPSTAPSAGGSYLSPAPGDTSSWASGPERWPRREHVVTVSKRRNTSVDENYEWDSEFPGDMELLETWHPGLASSRAHPELEPELGVKTPEKSCLLNTTHAPGPEARCAALREEFLAFRRRRDATRARLPVCQQSISYPEQATLL", "length": 1179 }, "evidence": [ { "id": "FB:FBgn0010473", "url": "https://alliancegenome.org/gene/FB:FBgn0010473#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q05BQ1-1", "protein_name": "Protein turtle homolog A", "gene_name": "Igsf9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIWCLRLTVLSLIISQGADGRRKPEVVSVVGRAGESAVLGCDLLPPAGHPPLHVIEWLRFGFLLPIFIQFGLYSPRIDPDYVGRVRLQTGASLQIEGLRVEDQGWYECRVLFLDQHSPEQDFANGSWVHLTVNSPPQFQETPPLVLEVKELEAVTLRCVARGSPQPYVTWKFRGQDLGKGQGQVQVQNGTLWIRRVERGSAGDYTCQASSSEGSITHATQLLVLGPPVIVVPPSNSTVNSSQDVSLACRAEAYPANLTYSWFQDGVNVFHISRLQSRVRILVDGSLWLQATQPDDAGHYTCVPSNGFLHPPSASAYLTVLYPAQVTVMPPETPLPTGMRGVIRCPVRANPPLLFVTWTKDGQALQLDKFPGWSLGPEGSLIIALGNENALGEYSCTPYNSLGTAGPSPVTQVLLKAPPAFIDQPKEEYFQEVGRELLIPCSARGDPPPIVSWAKVGRGLQGQAQVDSNNSLVLRPLTKEAQGRWECSASNAVARVTTSTNVYVLGTSPHVVTNVSVVPLPKGANVSWEPGFDGGYLQRFSVWYTPLAKRPDRAHHDWVSLAVPIGATHLLVPGLQAHAQYQFSVLAQNKLGSGPFSEIVLSIPEGLPTTPAAPGLPPTEIPPPLSPPRGLVAVRTPRGVLLHWDPPELIPGRLDGYILEGRQGSQGWEILDQGVAGTEIQLLVPGLIKDVLYEFRLVAFADSYVSDPSNVANISTSGLEVYPSRTQLPGLLPQPVLAGVVGGVCFLGVAVLVSILAACLMNRRRAARRHRKRLRQDPPLIFSPRGKSGSHSAPGSGSPDSVTKFKLQGSPVPSLRQSLLWGEPARPPSPHPDSPLGRGPLPLEPICRGPDGRFVMGPTVAPSQEKLCLERSEPRTSAKRLAQSFDCSSSSPSGVPQPLCITDISPVGQPLAAVPSPLPGPGPLLQYLSLPFFREMNVDGDWPPLEEPTPAPPPDFMDSQPCPTSSFLPPPDSPPANLRAVLPGTLMGVGVSSEPPYTALADWTLRERVLPGLLSAAPRGSLTSQSSGRGSASFLRPPSTAPSAGGSYLSPAPGDTSSWASGPERWPRREHVVTVSKRRNTSVDENYEWDSEFPGDMELLETWHPGLASSRTHPELEPELGVKTPEESCLLNPTHAAGPEARCAALREEFLAFRRRRDATRARLPAYQQSISYPEQATLL", "length": 1179 }, "evidence": [ { "id": "FB:FBgn0010473", "url": "https://alliancegenome.org/gene/FB:FBgn0010473#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q967D7-2", "protein_name": "Protein turtle", "gene_name": "tutl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGVCADLGSHRWCRALSTQHNTEKSKEQQQQSQPLEIPEQRASKCRGDIDRTTTTTIPASKTLTASPAKTAAFTVKTTRRRRSRRRAEGSSICVPIRRGQGSTPTPTIQVLQFVLVSLLALLAKNAQAHNIPEDAVHITAILGEGVIFNCHVEFPNDHPVPYVLQWDKKVSETGSDLPIYIWYESYPEHIEEGYKGRVSRVSQDSPFGSASLNLTNIRESDQGWYECKVVFLNRDPKQHKNGTWFHLDVHAPPRFSVTPEDIIYVNLGDSIILNCQADGTPTPEILWYKDANPVDPSPTVGIFNDGTELRISTIRHEDIGEYTCIARNGEGQVSHTARVIIAGGAVIMVPPTNQTKLEGEKVIFSCEAKAMPGNVTVRWYREGSPVREVAALETRVTIRKDGSLIINPIKPDDSGQYLCEVTNGIGDPQSASAYLSVEYPAKVTFTPTVQYLPFRLAGVVQCYIKSSPQLQYVTWTKDKRLLEPYQMKDIVVMANGSLLFTRVNEEHQGQYACTPYNAQGTAGASGVMDVLVRKPPAFTVEPETLYQRKVGDSVEMHCDALEAEGTERPTIKWQRQEGEQLTESQRNRIKISGGNITIENLRREDFGYYQCVVSNEVATLMAVTQLVIEGTQPHAPYNITGKATESSITLQWLPGYSGGSEYKQDYTIWFREAGVNDWQTISVTPSGSTQVTINGLASGTTYEFQVVGRNVLGDGMMSKVMTVRTLEDAPAAPRNVKAATQPPDSFFQLMPDEAGPKPGPPRNVSVTEVSNGFLITWQSPLERAHIVKFYTIKYRTDAQWKTLNRGQIRPEETQYLVKNLVGGRTYYFRVLANSEKSYESSDEVKFPVPARVKHKAITAGVVGGILFFIVAIILSVCAVKICNKRKRRKQEKEFNMVACRITDARNIAANNHHLHNRSTGSISSGQVPLKKYKQTRISSLTAILIAILHWIWPPDRCTNCHSIYSSPNLEDGDEDDGGGGRRRSVSRIQRSLDGRFVLDVEGVSKLGYSQQTLESGNVDVVDGGLFERRNSNVSQKSSSDDGGFLSRRNFITARASWRRPLVASSSQLSLQSAADSARGFLQGLLKIGAKQSAVPPNSQSYFDEAVSGARYQNVLRPYTSSNNLYGNADRSRPLHINTISGSLSQQQQLYTPSRISRIFSSSPQQLQPHHQQLLLSSGGSGAYPTHFSDLSTVYPPNSAERSSHNLSSRYRYYSQELPSLRTIQEETRRQQQQKQHPLEDHFVPLQLPSPPSWRSYYQSQASYRPRTRWYPRHHSRLFSNRQQQHEMLSPLPQLNLNLRNSMNPGGLEASPESRSSSSGFGSKNTSNHPGSTSEWRLLPPYRAPPSPPKHSGYFGGQQAQGQTPHGSYSYPRATTPPYTMAHWLEMISRLNAATDSNLPKAPCPVDVGSVDGHYEFDPATPTPSASSMLREDLNLHIDTHPYHHHTLGPLSGSLLHSHAPYGGGARKQRSLPAHLPRYDNVEVRLQAMREEFYAYRKRQAMQQMESVC", "length": 1508 }, "evidence": [ { "id": "HGNC:32326", "url": "https://alliancegenome.org/gene/HGNC:32326#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-729", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-729#orthology", "database": "AGR" }, { "id": "MGI:2685354", "url": "https://alliancegenome.org/gene/MGI:2685354#orthology", "database": "AGR" }, { "id": "RGD:1564717", "url": "https://alliancegenome.org/gene/RGD:1564717#orthology", "database": "AGR" }, { "id": "FB:FBgn0010473", "url": "https://alliancegenome.org/gene/FB:FBgn0010473#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9P2J2-1", "protein_name": "Protein turtle homolog A", "gene_name": "IGSF9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVWCLGLAVLSLVISQGADGRGKPEVVSVVGRAGESVVLGCDLLPPAGRPPLHVIEWLRFGFLLPIFIQFGLYSPRIDPDYVGRVRLQKGASLQIEGLRVEDQGWYECRVFFLDQHIPEDDFANGSWVHLTVNSPPQFQETPPAVLEVQELEPVTLRCVARGSPLPHVTWKLRGKDLGQGQGQVQVQNGTLRIRRVERGSSGVYTCQASSTEGSATHATQLLVLGPPVIVVPPKNSTVNASQDVSLACHAEAYPANLTYSWFQDNINVFHISRLQPRVRILVDGSLRLLATQPDDAGCYTCVPSNGLLHPPSASAYLTVLYPAQVTAMPPETPLPIGMPGVIRCPVRANPPLLFVSWTKDGKALQLDKFPGWSQGTEGSLIIALGNEDALGEYSCTPYNSLGTAGPSPVTRVLLKAPPAFIERPKEEYFQEVGRELLIPCSAQGDPPPVVSWTKVGRGLQGQAQVDSNSSLILRPLTKEAHGHWECSASNAVARVATSTNVYVLGTSPHVVTNVSVVALPKGANVSWEPGFDGGYLQRFSVWYTPLAKRPDRMHHDWVSLAVPVGAAHLLVPGLQPHTQYQFSVLAQNKLGSGPFSEIVLSAPEGLPTTPAAPGLPPTEIPPPLSPPRGLVAVRTPRGVLLHWDPPELVPKRLDGYVLEGRQGSQGWEVLDPAVAGTETELLVPGLIKDVLYEFRLVAFAGSFVSDPSNTANVSTSGLEVYPSRTQLPGLLPQPVLAGVVGGVCFLGVAVLVSILAGCLLNRRRAARRRRKRLRQDPPLIFSPTGKSAAPSALGSGSPDSVAKLKLQGSPVPSLRQSLLWGDPAGTPSPHPDPPSSRGPLPLEPICRGPDGRFVMGPTVAAPQERSGREQAEPRTPAQRLARSFDCSSSSPSGAPQPLCIEDISPVAPPPAAPPSPLPGPGPLLQYLSLPFFREMNVDGDWPPLEEPSPAAPPDYMDTRRCPTSSFLRSPETPPVSPRESLPGAVVGAGATAEPPYTALADWTLRERLLPGLLPAAPRGSLTSQSSGRGSASFLRPPSTAPSAGGSYLSPAPGDTSSWASGPERWPRREHVVTVSKRRNTSVDENYEWDSEFPGDMELLETLHLGLASSRLRPEAEPELGVKTPEEGCLLNTAHVTGPEARCAALREEFLAFRRRRDATRARLPAYRQPVPHPEQATLL", "length": 1179 }, "evidence": [ { "id": "FB:FBgn0010473", "url": "https://alliancegenome.org/gene/FB:FBgn0010473#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9U4G1-1", "protein_name": "Protein borderless", "gene_name": "bdl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPAKRSRTFRQSGSALLALLAIILLMNISCTSAARDHRRQTNLEAKVGSHVVFNCYIDFPFDAPIPYLVHWTKDNKKIFTWYEQETSTSELFNGRLHLVENHPEFGRASVNLTAIRESDQGWYHCQVSFPNRSPSVRNNGTAYHLAVQGGSLIRIPPVNQTIREGQTAFFHCVMKHPENSQASWYKDGVLLQEVQDLVRRFYMGPDGSLSIDPTMMSDLGEYECKVRNSDGELQTAKAFLNIQYKAKVIYAPPEVFLPYGQPAVLDCHFRANPPLKNLRWEKDGLLFDSYNVPGVFYKMNGSLFFAKVDENHAGSYTCTPYNDLGTDGPSPVISVIVLRPPIFSVTPKAIYIQKLGEAAELPCEAIDRDGNNRPSIIWGRKDGQPLPADRFSLSGGNLTITGLVEGDRGIYECSATNEAATITAEAELMIENIAPRAPYNLTANSTETCITIRWQPGYLRPNLEYTVWYRLMEAPEWRTLRVLDKKVMEATVQHLQPGKEYEFMVLSQDKYGDGMFSKQFRFQTLPSPIRADDFDAQQLQHDLGQVTAPAGGLGAPWNLTAISNQQGWLLHWEHPVQGLEGLRLYAVRWWKEPEHFLIGHAETFDNYYQLRHLKEDTLFKVQVLAVGTETQQSVPSHELLIDVPSQRKVRALIIGSSVGVIFLLCALCAFLYVKRSCLRHLFAKDSSASEDEDTAESGDCDSDEQDQRDRDSIKIRQST", "length": 719 }, "evidence": [ { "id": "MGI:2685354", "url": "https://alliancegenome.org/gene/MGI:2685354#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9UPX0-1", "protein_name": "Protein turtle homolog B", "gene_name": "IGSF9B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIWYVATFIASVIGTRGLAAEGAHGLREEPEFVTARAGESVVLRCDVIHPVTGQPPPYVVEWFKFGVPIPIFIKFGYYPPHVDPEYAGRASLHDKASLRLEQVRSEDQGWYECKVLMLDQQYDTFHNGSWVHLTINAPPTFTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTLLGASGKYQVSDGSLTVTSVSREDRGAYTCRAYSIQGEAVHTTHLLVQGPPFIVSPPENITVNISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDSGKYTCVPSNSLGRSPSASAYLTVQYPARVLNMPPVIYVPVGIHGYIRCPVDAEPPATVVKWNKDGRPLQVEKNLGWTLMEDGSIRIEEATEEALGTYTCVPYNTLGTMGQSAPARLVLKDPPYFTVLPGWEYRQEAGRELLIPCAAAGDPFPVITWRKVGKPSRSKHSALPSGSLQFRALSKEDHGEWECVATNVVTSITASTHLTVIGTSPHAPGSVRVQVSMTTANVSWEPGYDGGYEQTFSVWMKRAQFGPHDWLSLPVPPGPSWLLVDTLEPETAYQFSVLAQNKLGTSAFSEVVTVNTLAFPITTPEPLVLVTPPRCLIANRTQQGVLLSWLPPANHSFPIDRYIMEFRVAERWELLDDGIPGTEGEFFAKDLSQDTWYEFRVLAVMQDLISEPSNIAGVSSTDIFPQPDLTEDGLARPVLAGIVATICFLAAAILFSTLAACFVNKQRKRKLKRKKDPPLSITHCRKSLESPLSSGKVSPESIRTLRAPSESSDDQGQPAAKRMLSPTREKELSLYKKTKRAISSKKYSVAKAEAEAEATTPIELISRGPDGRFVMDPAEMEPSLKSRRIEGFPFAEETDMYPEFRQSDEENEDPLVPTSVAALKSQLTPLSSSQESYLPPPAYSPRFQPRGLEGPGGLEGRLQATGQARPPAPRPFHHGQYYGYLSSSSPGEVEPPPFYVPEVGSPLSSVMSSPPLPTEGPFGHPTIPEENGENASNSTLPLTQTPTGGRSPEPWGRPEFPFGGLETPAMMFPHQLPPCDVPESLQPKAGLPRGLPPTSLQVPAAYPGILSLEAPKGWAGKSPGRGPVPAPPAAKWQDRPMQPLVSQGQLRHTSQGMGIPVLPYPEPAEPGAHGGPSTFGLDTRWYEPQPRPRPSPRQARRAEPSLHQVVLQPSRLSPLTQSPLSSRTGSPELAARARPRPGLLQQAEMSEITLQPPAAVSFSRKSTPSTGSPSQSSRSGSPSYRPAMGFTTLATGYPSPPPGPAPAGPGDSLDVFGQTPSPRRTGEELLRPETPPPTLPTSGKLQRDRPAPATSPPERALSKL", "length": 1349 }, "evidence": [ { "id": "HGNC:32326", "url": "https://alliancegenome.org/gene/HGNC:32326#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-729", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-729#orthology", "database": "AGR" }, { "id": "MGI:2685354", "url": "https://alliancegenome.org/gene/MGI:2685354#orthology", "database": "AGR" }, { "id": "RGD:1564717", "url": "https://alliancegenome.org/gene/RGD:1564717#orthology", "database": "AGR" }, { "id": "FB:FBgn0010473", "url": "https://alliancegenome.org/gene/FB:FBgn0010473#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NYK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NYK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NYK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1394, "end_pos": 1396, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 527, "end_pos": 529, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 644, "end_pos": 646, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9NYK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 513, "end_pos": 609, "start_aa": "Ala", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9NYK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYK6" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 115, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 1394, "end_pos": 1396 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 527, "end_pos": 529 }, { "start_pos": 629, "end_pos": 631 }, { "start_pos": 644, "end_pos": 646 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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{ "uniprot_canonical_ac": "A0A8M9P3H0-1", "uniprot_ac": "A0A8M9P3H0", "uniprot_id": "A0A8M9P3H0_DANRE", "mass": { "chemical_mass": 53908.0, "monoisotopic_mass": 53908.0 }, "refseq": { "ac": "XP_021324607", "name": "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324607" }, "gene_names": [ { "name": "gcnt4b.1", "type": "recommended", "evidence": [ { "id": "A0A8M9P3H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3H0" } ] }, { "name": "gcnt4b.1", "type": "synonym", "evidence": [ { "id": "XP_021324607", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324607" } ] } ], "protein_names": [ { "name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4-like isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P3H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3H0/entry#names_and_taxonomy" } ] }, { "name": "beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021324607", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324607" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021324607.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324607" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P3H0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3H0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gcnt4b.1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3H0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091118-69", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-69", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P3H0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P3H0", "database": "AlphaFoldDB", "categories": [] }, { "id": "798652", "url": "https://www.ncbi.nlm.nih.gov/gene/798652", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003406", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003406", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:798652", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798652", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P3H0", "url": "https://www.orthodb.org/?gene=A0A8M9P3H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19297", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19297", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19297:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19297:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021324607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324607", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P3H0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P3H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IAI4", "url": "https://www.uniprot.org/uniprotkb/A0AC58IAI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IAI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IAI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091118-69", "url": "https://zfin.org/ZDB-GENE-091118-69", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MCLFVSSSGCRFCLNYSLNRTDYGPNLTCMRVITLPLSHTRMKTSWLHLKCKKVIFFVGFTLALLIYCFTISFLKVKGVQNGGKRAKKEISEMPRLTAKYGINCTRIYEMEPVEVAKTLVIRKQKSYVEPTDEIIVNATSDCDQFVSSLGYDAIQVTESEREFPLAYSLVVHRNAALVERLLRAVYVPHNIYCIHYDRKSSTDFMLAMNGLARCIPNVFIASKLERVQYAGISRLRADLNCLSDLLDSEVKWKYVINLCGQDFPLRTNAELVSDLKGLKGRNMVESKWPGAKNRRWSVHHLLKNKKFEFYNTPVSTSDKKRPPPYDIEMFVGSAYFTLSREFVYFVHWSYLARNFLAWSEDTFSPDEHFWATLVRVPGVPGEVPRSEADISELISKTRLVKWSAFEGRLYPRCTGVHVRKICIYGAAELRWLLNYGHWFANKVDPKVDPVLIECLEEKLAEKRRSFH", "length": 467, "header": "tr|A0A8M9P3H0-1|A0A8M9P3H0_DANRE Isoform 1 of Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4-like isoform X1 OS=Danio rerio OX=7955 GN=gcnt4b.1 PE=3 SV=3 CANONICAL=A0A8M9P3H0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P3H0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3H0/entry#A0A8M9P3H0-1", "sequence": { "sequence": "MCLFVSSSGCRFCLNYSLNRTDYGPNLTCMRVITLPLSHTRMKTSWLHLKCKKVIFFVGFTLALLIYCFTISFLKVKGVQNGGKRAKKEISEMPRLTAKYGINCTRIYEMEPVEVAKTLVIRKQKSYVEPTDEIIVNATSDCDQFVSSLGYDAIQVTESEREFPLAYSLVVHRNAALVERLLRAVYVPHNIYCIHYDRKSSTDFMLAMNGLARCIPNVFIASKLERVQYAGISRLRADLNCLSDLLDSEVKWKYVINLCGQDFPLRTNAELVSDLKGLKGRNMVESKWPGAKNRRWSVHHLLKNKKFEFYNTPVSTSDKKRPPPYDIEMFVGSAYFTLSREFVYFVHWSYLARNFLAWSEDTFSPDEHFWATLVRVPGVPGEVPRSEADISELISKTRLVKWSAFEGRLYPRCTGVHVRKICIYGAAELRWLLNYGHWFANKVDPKVDPVLIECLEEKLAEKRRSFH", "length": 467, "header": "tr|A0A8M9P3H0-1|A0A8M9P3H0_DANRE Isoform 1 of Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4-like isoform X1 OS=Danio rerio OX=7955 GN=gcnt4b.1 PE=3 SV=3 CANONICAL=A0A8M9P3H0-1" }, "locus": {} }, { "isoform_ac": "A0AC58IAI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3H0/entry#A0AC58IAI4-1", "sequence": { "sequence": "MKTSWLHLKCKKVIFFVGFTLALLIYCFTISFLKVKGVQNGGKRAKKEISEMPRLTAKYGINCTRIYEMEPVEVAKTLVIRKQKSYVEPTDEIIVNATSDCDQFVSSLGYDAIQVTESEREFPLAYSLVVHRNAALVERLLRAVYVPHNIYCIHYDRKSSTDFMLAMNGLARCIPNVFIASKLERVQYAGISRLRADLNCLSDLLDSEVKWKYVINLCGQDFPLRTNAELVSDLKGLKGRNMVESKWPGAKNRRWSVHHLLKNKKFEFYNTPVSTSDKKRPPPYDIEMFVGSAYFTLSREFVYFVHWSYLARNFLAWSEDTFSPDEHFWATLVRVPGVPGEVPRSEADISELISKTRLVKWSAFEGRLYPRCTGVHVRKICIYGAAELRWLLNYGHWFANKVDPKVDPVLIECLEEKLAEKRRSFH", "length": 426, "header": "tr|A0AC58IAI4-1|A0AC58IAI4_DANRE Computationally mapped isoform of Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4-like isoform X2 OS=Danio rerio OX=7955 GN=gcnt4b.1 PE=3 SV=1 CANONICAL=A0A8M9P3H0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:798652", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798652", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ARU0-1", "protein_name": "Glucosaminyl (N-acetyl) transferase 4", "gene_name": "Gcnt4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKILRCCFKYTLQQKVFILFLTLWLFSLLKLLNVGRLLFPQRDIYLVEYSLSTSPFVRNRFPDTGDAARDAVNCSGVYEHEPLEIGKSLEIRRRNIIDLEDGDVAVMTSDCDIYQTLRQYHEKPVSRVEEDFPIAYSLVVHKDAIMVERLIRAIYNQHNLYCIHYDLKSPDAFKAAMNNLAKCFSNIFIASKLEAVEYAHISRLQADWNCLSDLLKSSVQWKYVINLCGQDFPLKSNFELVTELKKLRGRNMLETVRPPTGKMERFTYHHELRQVPYEYMKLPVKTNVSKGAPPHDIEVFVGSAYFVLSQAFVKYIFNSSLVKDFFAWSKDTYSPDEHFWATLIRIPGIPGGISRSSQDVSDLQSKTRLVKWNYYEGFFYPNCTGSHLRSVCIYGAAELRWLIKEGHWFANKFDSKVDPVLIKCLAEKLEEQQRKLIALSSEKSITEGNPKATHKITTGLRASDTES", "length": 467 }, "evidence": [ { "id": "HGNC:17973", "url": "https://alliancegenome.org/gene/HGNC:17973#orthology", "database": "AGR" }, { "id": "MGI:2684919", "url": "https://alliancegenome.org/gene/MGI:2684919#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9Q781-1", "protein_name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4", "gene_name": "gcnt4b.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKPLKLHLKLRNVIFVFGTLGLLCTTVIFLRGNGEKQEAGLSLRQQLTVKYGINCTKIYEMEPVEVGKSLVIRKQKIYKGLTDAAIANATIDCEWFVSSQGYNDIQVTESEREFPLAYSLVVHQDAALVERLLRAVYVPHNIYCIHYDRKSSTDFMLAMNGLARCIPNVFIASKLERVQYAGISRLRADLNCLSDLLDSEVKWKYVINLCGQDFPLRTNAELVSDLKGLKGRNMVESKWPGGKKIRWSVHHLLKNNDSEYYDFPVSTPEEKPPPPHNIEMFVGSAYFTLSREFVYFVHWSSLAKDFLAWSEDTFSPDEHFWATLVRVPGVPGEVPRSDPEISELISKTHLVKWSYLENDLYPECTGVSVRSVCIYGAAELRWLLNYGHWFANKVDPTVDPVLIECLEEKLEEKRRRLAVN", "length": 420 }, "evidence": [ { "id": "HGNC:17973", "url": "https://alliancegenome.org/gene/HGNC:17973#orthology", "database": "AGR" }, { "id": "MGI:2684919", "url": "https://alliancegenome.org/gene/MGI:2684919#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q649-1", "protein_name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4", "gene_name": "Gcnt4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIFRCCFKYTLQQKLFILLLTLWLFSLLKLLNVGRLLFPQRDIYLVEYSLSTSPFVRNRFPESGDAARDNVNCSGVYEHEPLEIGKSLEIRRRSIIDLEDGDVVAMTSDCDVYQTLRQYHEKLVSREEEDFPIAYSLVVHKDAIMVERLIRAIYNQHNLYCIHYDLKSPDTFKAAMNNLAKCFPNIFIASKLETVEYAHISRLQADWNCLSDLLKSSVQWKYVINLCGQDFPLKSNFELVTELKSLQGRNMLETVRPPSAKTERFTYHHELRQVPYDYMKLPVKTNVSKGAPPHNIQVFVGSAYFVLSRAFVKYIFNSSLVEDFFAWSKDTYSPDEHFWATLIRIPGIPGGISSSSQDVSDLQSKTRLVKWFYYEGFLYPNCTGSHLRSVCIYGAAELRWLLNEGHWFANKFDSKVDPILMKCLAEKLEEQQRKLIALSSEKFMTEGTRQSHTL", "length": 455 }, "evidence": [ { "id": "HGNC:17973", "url": "https://alliancegenome.org/gene/HGNC:17973#orthology", "database": "AGR" }, { "id": "MGI:2684919", "url": "https://alliancegenome.org/gene/MGI:2684919#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091118-69", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-69#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q71SG7-1", "protein_name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4", "gene_name": "gcnt4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRRCAVLHRLRCKFYVFVVSLFVVVKLVYLKISMDNSIYIEPYGVTRRSLKPQPLDGINCTAIYDLEPVEIGKSLEMRRKKIVEVDDGRIASFTADCKSYIEQRRYNEVLVTDEECNFPIAYSLVVHKNSAMVERILRAIYAPQNIYCIHYDQKSTKDFIAAMKNLESCFPNVFIASKIESVQYAHITRLKADLNCLSDLLSSEVKWKYVINLCGQDFPLKSNYELVTELRKLNGANMLETSRPSKVKKQRFQFRYQLKDVSYEYQKMPVKTSIAKDPPPHNIEMFVGSAYFVLSRDFVTYVMNNQLAKDFLQWSVDTYSPDEHFWASMARVPGVPGELARSEPDVSDLKSRTRLVKWNYLEERLYPKCTGTHRRSVCIYGAAELRWLLEDGHWFANKFDPKVDPVIIKCLEEKLEEKQLQQCLRRVS", "length": 428 }, "evidence": [ { "id": "HGNC:17973", "url": "https://alliancegenome.org/gene/HGNC:17973#orthology", "database": "AGR" }, { "id": "MGI:2684919", "url": "https://alliancegenome.org/gene/MGI:2684919#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9P109-1", "protein_name": "Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4", "gene_name": "GCNT4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIFKCYFKHTLQQKVFILFLTLWLLSLLKLLNVRRLFPQKDIYLVEYSLSTSPFVRNRYTHVKDEVRYEVNCSGIYEQEPLEIGKSLEIRRRDIIDLEDDDVVAMTSDCDIYQTLRGYAQKLVSKEEKSFPIAYSLVVHKDAIMVERLIHAIYNQHNIYCIHYDRKAPDTFKVAMNNLAKCFSNIFIASKLEAVEYAHISRLQADLNCLSDLLKSSIQWKYVINLCGQDFPLKSNFELVSELKKLNGANMLETVKPPNSKLERFTYHHELRRVPYEYVKLPIRTNISKEAPPHNIQIFVGSAYFVLSQAFVKYIFNNSIVQDFFAWSKDTYSPDEHFWATLIRVPGIPGEISRSAQDVSDLQSKTRLVKWNYYEGFFYPSCTGSHLRSVCIYGAAELRWLIKDGHWFANKFDSKVDPILIKCLAEKLEEQQRDWITLPSEKLFMDRNLTTTS", "length": 453 }, "evidence": [ { "id": "HGNC:17973", "url": "https://alliancegenome.org/gene/HGNC:17973#orthology", "database": "AGR" }, { "id": "MGI:2684919", "url": "https://alliancegenome.org/gene/MGI:2684919#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091118-69", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-69#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P3H0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3H0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glycosyltransferase activity", "id": "GO:0016757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016757", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P3H0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3H0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 137, "end_pos": 139 }, { "start_pos": 15, "end_pos": 17 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 26, "end_pos": 28 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P8J3-1", "uniprot_ac": "A0A8M9P8J3", "uniprot_id": "A0A8M9P8J3_DANRE", "mass": { "chemical_mass": 20853.0, "monoisotopic_mass": 20853.0 }, "refseq": { "ac": "XP_068070335", "name": "telethonin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070335" }, "gene_names": [ { "name": "zmp:0000000930", "type": "recommended", "evidence": [ { "id": "A0A8M9P8J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8J3" } ] }, { "name": "zmp:0000000930", "type": "synonym", "evidence": [ { "id": "XP_068070335", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070335" } ] } ], "protein_names": [ { "name": "Telethonin isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P8J3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8J3/entry#names_and_taxonomy" } ] }, { "name": "telethonin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_068070335", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070335" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068070335", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070335" } ] } ], "disease": [ { "disease_id": "DOID:0110281", "recommended_name": { "id": "DOID:0110281", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110281", "name": "autosomal recessive limb-girdle muscular dystrophy type 2G", "description": "An autosomal recessive limb-girdle muscular dystrophy that has_material_basis_in mutation in the gene encoding telethonin (TCAP)." }, "synonyms": [ { "id": "DOID:0110281", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110281", "name": "LGMD2G", "description": "" }, { "id": "DOID:0110281", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110281", "name": "muscular dystrophy, limb-girdle, type 2G", "description": "" }, { "id": "DOID:0110281", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110281", "name": "limb-girdle muscular dystrophy due to telethonin deficiency", "description": "" }, { "id": "MONDO:0011170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011170", "name": "autosomal recessive limb-girdle muscular dystrophy type 2G", "description": "Autosomal recessive limb-girdle muscular dystrophy type 2G (LGMD2G) is a mild subtype of autosomal recessive limb-girdle muscular dystrophy characterized by a variable onset (ranging from infancy to adolescence) of progressive proximal upper and lower limb muscle weakness and atrophy. Mild scapular winging, calf hypertrophy, and lack of respiratory and cardiac involvement are also observed." }, { "id": "MONDO:0011170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011170", "name": "LGMD2G", "description": "" }, { "id": "MONDO:0011170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011170", "name": "TCAP autosomal recessive limb-girdle muscular dystrophy", "description": "" }, { "id": "MONDO:0011170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011170", "name": "Tcap autosomal recessive limb-girdle muscular dystrophy", "description": "" }, { "id": "MONDO:0011170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011170", "name": "autosomal recessive limb-girdle muscular dystrophy caused by mutation in TCAP", "description": "" }, { "id": "MONDO:0011170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011170", "name": "autosomal recessive limb-girdle muscular dystrophy caused by mutation in Tcap", "description": "" }, { "id": "MONDO:0011170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011170", "name": "limb-girdle muscular dystrophy due to telethonin deficiency", "description": "" }, { "id": "MONDO:0011170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011170", "name": "muscular dystrophy, limb-girdle, autosomal recessive 7", "description": "" }, { "id": "MONDO:0011170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011170", "name": "muscular dystrophy, limb-girdle, type 2G", "description": "" }, { "id": "MONDO:0011170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011170", "name": "limb-girdle muscular dystrophy, type 2G", "description": "" }, { "id": "MIM:601954", "resource": "MIM", "url": "https://www.omim.org/entry/601954", "name": "Muscular dystrophy, limb-girdle, autosomal recessive 7", "description": "Muscular dystrophy, limb-girdle, autosomal recessive 7" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110281", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110281" } ] }, { "disease_id": "DOID:0110328", "recommended_name": { "id": "DOID:0110328", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110328", "name": "hypertrophic cardiomyopathy 25", "description": "A familial hypertrophic cardiomyopathy that has_material_basis_in heterozygous mutation in the TCAP gene on chromosome 17q12." }, "synonyms": [ { "id": "DOID:0110328", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110328", "name": "CMH25", "description": "" }, { "id": "DOID:0110328", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110328", "name": "cardiomyopathy familial hypertrophic 25", "description": "" }, { "id": "MONDO:0011843", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011843", "name": "hypertrophic cardiomyopathy 25", "description": "Any hypertrophic cardiomyopathy in which the cause of the disease is a mutation in the TCAP gene." }, { "id": "MONDO:0011843", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011843", "name": "CMH25", "description": "" }, { "id": "MONDO:0011843", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011843", "name": "TCAP hypertrophic cardiomyopathy", "description": "" }, { "id": "MONDO:0011843", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011843", "name": "Tcap hypertrophic cardiomyopathy", "description": "" }, { "id": "MONDO:0011843", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011843", "name": "cardiomyopathy, familial hypertrophic, type 25", "description": "" }, { "id": "MONDO:0011843", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011843", "name": "cardiomyopathy, hypertrophic, 25", "description": "" }, { "id": "MONDO:0011843", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011843", "name": "hypertrophic cardiomyopathy caused by mutation in TCAP", "description": "" }, { "id": "MONDO:0011843", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011843", "name": "hypertrophic cardiomyopathy type 25", "description": "" }, { "id": "MONDO:0011843", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011843", "name": "cardiomyopathy, familial hypertrophic, 25", "description": "" }, { "id": "MIM:607487", "resource": "MIM", "url": "https://www.omim.org/entry/607487", "name": "Cardiomyopathy, familial hypertrophic, 25", "description": "Cardiomyopathy, familial hypertrophic, 25" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110328" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8J3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zmp:0000000930", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8J3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-933", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-933", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100151586", "url": "https://www.ncbi.nlm.nih.gov/gene/100151586", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015667", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015667", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100151586", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100151586", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P8J3", "url": "https://www.orthodb.org/?gene=A0A8M9P8J3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15143:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15143:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09470", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09470", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_068070335", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070335", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P8J3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8J3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P8J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8J3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HL51", "url": "https://www.uniprot.org/uniprotkb/A0AC58HL51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HL51-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HL51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HL83", "url": "https://www.uniprot.org/uniprotkb/A0AC58HL83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HL83-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HL83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-933", "url": "https://zfin.org/ZDB-GENE-130530-933", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MHCLSRTPRSYLLNSYSDLQETDELSRESYEATWLDLLMETRPEYKMTLAEKDSMKKESYESKQVVHFTVRRFPNQTIQMGRDREPMQEYRLPYKNILPIPIFVPRDVTQPDVTRSPSPSVKSSTDTEASLSGVCLHKREISSITEHKPMVIQPRSPDFRASSLISPPRDTLRFQRRE", "length": 178, "header": "tr|A0A8M9P8J3-1|A0A8M9P8J3_DANRE Isoform 1 of Telethonin isoform X1 OS=Danio rerio OX=7955 GN=zmp:0000000930 PE=4 SV=1 CANONICAL=A0A8M9P8J3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P8J3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8J3/entry#A0A8M9P8J3-1", "sequence": { "sequence": "MHCLSRTPRSYLLNSYSDLQETDELSRESYEATWLDLLMETRPEYKMTLAEKDSMKKESYESKQVVHFTVRRFPNQTIQMGRDREPMQEYRLPYKNILPIPIFVPRDVTQPDVTRSPSPSVKSSTDTEASLSGVCLHKREISSITEHKPMVIQPRSPDFRASSLISPPRDTLRFQRRE", "length": 178, "header": "tr|A0A8M9P8J3-1|A0A8M9P8J3_DANRE Isoform 1 of Telethonin isoform X1 OS=Danio rerio OX=7955 GN=zmp:0000000930 PE=4 SV=1 CANONICAL=A0A8M9P8J3-1" }, "locus": {} }, { "isoform_ac": "A0AC58HL51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8J3/entry#A0AC58HL51-1", "sequence": { "sequence": "METRPEYKMTLAEKDSMKKESYESKQVVHFTVRRFPNQTIQMGRDREPMQEYRLPYKNILPIPIFVPRDVTQPDVTRSPSPSVKSSTDTEASLSGVCLHKREISSITEHKPMVIQPRSPDFRASSLISPPRDTLRFQRRE", "length": 140, "header": "tr|A0AC58HL51-1|A0AC58HL51_DANRE Computationally mapped isoform of Telethonin isoform X2 OS=Danio rerio OX=7955 GN=zmp:0000000930 PE=4 SV=1 CANONICAL=A0A8M9P8J3-1" }, "locus": {} }, { "isoform_ac": "A0AC58HL83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8J3/entry#A0AC58HL83-1", "sequence": { "sequence": "MTLAEKDSMKKESYESKQVVHFTVRRFPNQTIQMGRDREPMQEYRLPYKNILPIPIFVPRDVTQPDVTRSPSPSVKSSTDTEASLSGVCLHKREISSITEHKPMVIQPRSPDFRASSLISPPRDTLRFQRRE", "length": 132, "header": "tr|A0AC58HL83-1|A0AC58HL83_DANRE Computationally mapped isoform of Telethonin isoform X3 OS=Danio rerio OX=7955 GN=zmp:0000000930 PE=4 SV=1 CANONICAL=A0A8M9P8J3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100151586", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100151586", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LAZ2-1", "protein_name": "Telethonin", "gene_name": "Tcap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGFLYRLGYVILLVKGPHYDKPLSSLNKGEQAEDSAKVARGCPRAWSEVVFAACQTPGGATLRTQAPSRASRRLWKLTSDLRAIRIWVPQPPPWIQSPITTKLSCQVSEENQERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHRQGQCQAVVQRSPWLVMRLGILGRGLQEYQLPYQRVLPLPIFTPTKVGATKEEREETPIQLRELLALETALGGQCVERQDVAEITKQLPPVVPVSKPGPLRRTLSRSMSQEAQRG", "length": 264 }, "evidence": [ { "id": "HGNC:11610", "url": "https://alliancegenome.org/gene/HGNC:11610#orthology", "database": "AGR" }, { "id": "RGD:1592387", "url": "https://alliancegenome.org/gene/RGD:1592387#orthology", "database": "AGR" }, { "id": "MGI:1330233", "url": "https://alliancegenome.org/gene/MGI:1330233#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-933", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-933#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QCX4-1", "protein_name": "Telethonin", "gene_name": "tcap", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQVCSVLEKKGGCVVGAELSCSVREENPNKRESYTADWRSINMKTQPEDRQSMLMSDDSRRESLSRYWQVRPLHQACPSGVRRVGTVDTGVREHQLLPYRNSLPLPIFKPAELGVRLGRGAPHTLEDLPPVRIPDGVCPDKRAVEQITRDLPPVKPMRMEFAKAPRALGRSMSQEAQRG", "length": 179 }, "evidence": [ { "id": "HGNC:11610", "url": "https://alliancegenome.org/gene/HGNC:11610#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O15273-1", "protein_name": "Telethonin", "gene_name": "TCAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATSELSCEVSEENCERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHQQGQCQVLVQRSPWLMMRMGILGRGLQEYQLPYQRVLPLPIFTPAKMGATKEEREDTPIQLQELLALETALGGQCVDRQEVAEITKQLPPVVPVSKPGALRRSLSRSMSQEAQRG", "length": 167 }, "evidence": [ { "id": "HGNC:11610", "url": "https://alliancegenome.org/gene/HGNC:11610#orthology", "database": "AGR" }, { "id": "RGD:1592387", "url": "https://alliancegenome.org/gene/RGD:1592387#orthology", "database": "AGR" }, { "id": "MGI:1330233", "url": "https://alliancegenome.org/gene/MGI:1330233#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-933", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-933#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70548-1", "protein_name": "Telethonin", "gene_name": "Tcap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATSELSCQVSEENQERREAFWAEWKDLTLSTRPEEGCSLHEEDTQRHETYHRQGQCQAVVQRSPWLVMRLGILGRGLQEYQLPYQRVLPLPIFTPTKVGASKEEREETPIQLRELLALETALGGQCVERQDVAEITKQLPPVVPVSKPGPLRRTLSRSMSQEAQRG", "length": 167 }, "evidence": [ { "id": "HGNC:11610", "url": "https://alliancegenome.org/gene/HGNC:11610#orthology", "database": "AGR" }, { "id": "RGD:1592387", "url": "https://alliancegenome.org/gene/RGD:1592387#orthology", "database": "AGR" }, { "id": "MGI:1330233", "url": "https://alliancegenome.org/gene/MGI:1330233#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-933", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-933#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PDK8-1", "uniprot_ac": "A0A8M9PDK8", "uniprot_id": "A0A8M9PDK8_DANRE", "mass": { "chemical_mass": 53439.0, "monoisotopic_mass": 53439.0 }, "refseq": { "ac": "XP_021322574", "name": "zinc-binding protein A33", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322574" }, "gene_names": [ { "name": "LOC101882614", "type": "recommended", "evidence": [ { "id": "A0A8M9PDK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK8" } ] }, { "name": "LOC101882614", "type": "synonym", "evidence": [ { "id": "XP_021322574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322574" } ] } ], "protein_names": [ { "name": "Zinc-binding protein A33", "type": "synonym", "evidence": [ { "id": "A0A8M9PDK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK8/entry#names_and_taxonomy" } ] }, { "name": "zinc-binding protein A33", "type": "synonym", "evidence": [ { "id": "XP_021322574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322574" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322574.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322574" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101882614", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK8", "locus": {} } ], "crossref": [ { "id": "A0A8M9PDK8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PDK8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19800", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19800", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101882614", "url": "https://www.ncbi.nlm.nih.gov/gene/101882614", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101882614", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882614", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PDK8", "url": "https://www.orthodb.org/?gene=A0A8M9PDK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322574", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MASALSLYLMCPVCLSDFKDPVSLPCEHVLCRQCASRYLESSKGPHKCPECRQNFTRTDLKGIRVLRNVVDAIQEQRKKKQLIQPNAEEMLCSEHKEPLKLFCVNDQRLVCLICKEGMKHSGHSFKPVKEAKEMSEKMVNKALSFILDDNKQMGDMILNQTLEITKSKERAKHLETLMHAQFKKMHDFLLKKEEDAMRQIQKAANSAEESMKHNGSLLSKLQIKGNSQVSILESGLKINQPERFLEWWSKDGFPLVNEISESKNIKFAIPTKFKSKHDGVRVICDHFTLGPYETDLPLMVWRDMLGPVKRDLSDSSTMDKDLKLAFKKENHQQPQGEDYFARFQKFHNGYRENYVESIQPGQVYWEVDIEAEPGWERGLTVRYYPKEKNTSLWQTLFNKGFENISLSVKNGRLYAVRGDKETLIANQTKPRRVGVYVDSVKHQVVFCNADSISLIHTVWCGDQ", "length": 463, "header": "tr|A0A8M9PDK8-1|A0A8M9PDK8_DANRE Isoform 1 of Zinc-binding protein A33 OS=Danio rerio OX=7955 GN=LOC101882614 PE=4 SV=2 CANONICAL=A0A8M9PDK8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PDK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK8/entry#A0A8M9PDK8-1", "sequence": { "sequence": "MASALSLYLMCPVCLSDFKDPVSLPCEHVLCRQCASRYLESSKGPHKCPECRQNFTRTDLKGIRVLRNVVDAIQEQRKKKQLIQPNAEEMLCSEHKEPLKLFCVNDQRLVCLICKEGMKHSGHSFKPVKEAKEMSEKMVNKALSFILDDNKQMGDMILNQTLEITKSKERAKHLETLMHAQFKKMHDFLLKKEEDAMRQIQKAANSAEESMKHNGSLLSKLQIKGNSQVSILESGLKINQPERFLEWWSKDGFPLVNEISESKNIKFAIPTKFKSKHDGVRVICDHFTLGPYETDLPLMVWRDMLGPVKRDLSDSSTMDKDLKLAFKKENHQQPQGEDYFARFQKFHNGYRENYVESIQPGQVYWEVDIEAEPGWERGLTVRYYPKEKNTSLWQTLFNKGFENISLSVKNGRLYAVRGDKETLIANQTKPRRVGVYVDSVKHQVVFCNADSISLIHTVWCGDQ", "length": 463, "header": "tr|A0A8M9PDK8-1|A0A8M9PDK8_DANRE Isoform 1 of Zinc-binding protein A33 OS=Danio rerio OX=7955 GN=LOC101882614 PE=4 SV=2 CANONICAL=A0A8M9PDK8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101882614", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882614", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDK8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 426, "end_pos": 428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PDK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK8" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 87, "end_pos": 128, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PDK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK8" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 291, "end_pos": 463, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PDK8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK8" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 52, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 389, "end_pos": 391 }, { "start_pos": 403, "end_pos": 405 }, { "start_pos": 426, "end_pos": 428 }, { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PDQ0-1", "uniprot_ac": "A0A8M9PDQ0", "uniprot_id": "A0A8M9PDQ0_DANRE", "mass": { "chemical_mass": 273301.0, "monoisotopic_mass": 273301.0 }, "refseq": { "ac": "XP_021324938", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324938" }, "gene_names": [ { "name": "LOC101886224", "type": "recommended", "evidence": [ { "id": "A0A8M9PDQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDQ0" } ] }, { "name": "LOC101886224", "type": "synonym", "evidence": [ { "id": "XP_021324938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324938" } ] } ], "protein_names": [ { "name": "SEA domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PDQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDQ0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021324938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324938" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021324938.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324938" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDQ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101886224", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDQ0", "locus": {} } ], "crossref": [ { "id": "A0A8M9PDQ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PDQ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "101886224", "url": "https://www.ncbi.nlm.nih.gov/gene/101886224", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101886224", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886224", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PF01390", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01390", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021324938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324938", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PDQ0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFVTVAGLACGSVINSLSVWLEENFGKFSFFVNYEDLINEGFVQKLDPVSTSQSAPLTSGVLNNSENQEQSTLTTKQTQSSQNIILKQTSSATVSTDPLSSVASPDRSPHQLSTTIASGNVLTSHLTQNAPITTFNILGSSKPSVPVDFTTAAVPEDQSSTTVPFDQSSNIGPSLLSTAVPNQSSTTAHNGPLTDKGYLYSSNTYVPDDSTAAAVPNGLSSTTADNGPVTTKEPLDSKTYVPVDFTTAAVSAGQSSTSVSLDESSNVVFPSLLTTTAASDQSSTNAPNYPVTTTGLLSSSTVTVSNDYTTAAVPIDLSSTTLSSGHLSNVFPNDMSDTTAYNVPITTKEPLDSSRTYIHVDSTTATAPVGQSGTTVPLDQSSNIVPPSLLTTTAASGQSSTNAPNGSITTKDPLRSKTSVPDDSTTAPVPTDLSNTTADNDPVTTEEPLDSKTYVSVDSTTAAVPVGQSSTAVPLDQSSNIVHPSLLTTTTASDQLSTNATNGPVTTKDPLSSKTTALDDSTTAPVPAGQSTTTLSLGHSTSGVPNDLFSTTADNGPVTTKEPLDSKTYVSVDSTTAAVPTVQSSTTVSPDQSSNIVLPSILTTTTASDQSSTNAPNGHITTMGPLSSKTSVSDDSTTASVPAGHSSTTLSPGQPISGVPNDLSSTTTNNRPITTKEPLESKTYVSVDSTTAAVLTGQSSTSVPLDQSSNTVLPSILITIAASDQSSTIAPNGGITTKDPLSSKTSVPNDSTTAQVLASQSSTTLSPGQSISGIPNDLSNTTADDSSVTTKEPLDSKTYVSVDSTTAAVPVGQSSTTVSPDQSSNIVLPSLLTTTTASDQSSTNAPNGPVTTKDPLSSKTSVPDDSIATVVPTELSSTPLSPGHPSNAVPNDLLSTTTNNGPITTKEPLEPKTYVSVDSTTAAVPVGQSSTTVPLEKSSNIVPPSLLTTTAASGQSSTKAPNGSITTKDPLSSKTSVPNDSTNATGPAGQSITTLSPGQSISGVPNDLSSTTADDSSVTTKEPLDSKTYVSVDSTTAAVPVGQSSTTVPLDQSSNVVLPSLLITTAASDQSSTNAPNGGITTKDPLSSKTSSLNDSTTAPVPAGQSSTTLSPGQSISGVPDDLSSTTANNNSVTTKEPLDLNTYVSVESTTAAVPEGQSSTTVSPDQSSNIVLPSLLTTTTASDQSSTNAPNGPVTTKDPLSSKTSVPDDSIATVVPTELSSTPLSPGQSISGVPNDLSSTTTNNGPITTKEPLEPKTYVSDDSSTAAVPVGQSSTTVPLDQSSNIVHPSLLTTTAASGQSSTKAPNGSISTKDPLSSKTSVPNDSTNATGPAGQSTTTLSPGQSISGVPNDLSNTTADDSSVTTKEPLDSKTYVSVDSTTAAVPVGQSSTTVSLDQSSNVVLPSLLTTTAASDQSSTNATNGPITTKDPLRSKTSVPDDSIATVVSTELSSTPLSPGRPSNAVPTDLLSTTADNGPVNTKEPLDSKTYVSVDSTTAAVPEGQTSITVPLDQSSNLVLSSLLTTSAASDQSSTNTSNSPITPKDPLSSKTSVPDDSTTAPVPAGHSSTTLSPNHSISGIPNDLSSTTTDNGPVTAKEPLDSKTSVPVNFTTAPVPTDLSITTLSSGHLNSGVPNDLSSTTTNNRPITTKETLEPKTYVSVDSTTAAVPVGQSSITVPLDQSSNIVPPSLLTTTAASGQSSTKAPNGSITTKDPLSSKTSVPNDSTNATGPAGQSTTTLSSGQPISGVPDDLSSTTADDNSVTTKEPLDSKTTVSVDSTTAAVPVGQSSTTVPLDQSSNVVLPSLLTTTPASDQSSTNATNGSITTKDPLSSKTTVPNDSATASVLAGQSTTTLSSGHSMSGVPNDLSSTTDKNGPVTTKETLDSSYTYVPIDSTTETVHKYESSTTVPLDHSSNLVFPSLLTTKAAFDQSRTTAPNGPFTIIDLLGSKTSVPVDSTTAAIPAYQSSTTVPLDQSSNVVLPSLLTTTAASDQLSITAPNSPITTKPLLSSKTSVPDDSTIAPFPTDLSSTTLSPGHSISGVPNYLSSTTASNGPVTTKDSLDSSYTTFPTEFKTTAVPDYGSSTKDPLDQSSNVLSITTANNGPLPTKDQSSNVVLNPLTATVPNVQSSTTGPNGPIITKDILGSSKSSVPDKFTTAAGPTDLSSTAPSPGHSNNAVPNDWSIATADNGPVMTKEPLYSKTSVLIDSTPVSVPADQSSTIVLLDQSSNVVHSSLLTAVASAQTDTTSPNSPMTSSKTLVPDNSITTADPTNLSITIVSLGHSSNAVPNDLSNTTANHGQVTTKETVDYSKTSLPVDSTTAAPPADKSSTTVFLDQSRNVVVSSLSTTTVSKDQPNTSASNGSQTTKDLLGSSKASVPDDSTTTVSTDLSSTTLSPGYPSIAVPNDLLSTTADNRPVTTKEPLDSKTSVLADSTTVVVLADQPSPTLLLDRSNNVVIHSLITTTVASDQSTTSALNNPVSSTAANRFTTTIIFATSAHSNIVTTSTTSSSPPTTYSSTKASTGSAMPGEVFVVLQIRLQTQYIDAYNNPASVEYQSLSRNITIELNRLYQSIYGTRFLRCYVIRFWPGSVGVDTQIIFQNQNVLPNATSIEETLSTAITDSNVFLPVIPSSITVVESLGSINTTSQTQTLQSVSTNQTSSAVAPVLSSVLFTLWLFLRNEIL", "length": 2680, "header": "tr|A0A8M9PDQ0-1|A0A8M9PDQ0_DANRE Isoform 1 of SEA domain-containing protein OS=Danio rerio OX=7955 GN=LOC101886224 PE=4 SV=3 CANONICAL=A0A8M9PDQ0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PDQ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDQ0/entry#A0A8M9PDQ0-1", "sequence": { "sequence": "MFVTVAGLACGSVINSLSVWLEENFGKFSFFVNYEDLINEGFVQKLDPVSTSQSAPLTSGVLNNSENQEQSTLTTKQTQSSQNIILKQTSSATVSTDPLSSVASPDRSPHQLSTTIASGNVLTSHLTQNAPITTFNILGSSKPSVPVDFTTAAVPEDQSSTTVPFDQSSNIGPSLLSTAVPNQSSTTAHNGPLTDKGYLYSSNTYVPDDSTAAAVPNGLSSTTADNGPVTTKEPLDSKTYVPVDFTTAAVSAGQSSTSVSLDESSNVVFPSLLTTTAASDQSSTNAPNYPVTTTGLLSSSTVTVSNDYTTAAVPIDLSSTTLSSGHLSNVFPNDMSDTTAYNVPITTKEPLDSSRTYIHVDSTTATAPVGQSGTTVPLDQSSNIVPPSLLTTTAASGQSSTNAPNGSITTKDPLRSKTSVPDDSTTAPVPTDLSNTTADNDPVTTEEPLDSKTYVSVDSTTAAVPVGQSSTAVPLDQSSNIVHPSLLTTTTASDQLSTNATNGPVTTKDPLSSKTTALDDSTTAPVPAGQSTTTLSLGHSTSGVPNDLFSTTADNGPVTTKEPLDSKTYVSVDSTTAAVPTVQSSTTVSPDQSSNIVLPSILTTTTASDQSSTNAPNGHITTMGPLSSKTSVSDDSTTASVPAGHSSTTLSPGQPISGVPNDLSSTTTNNRPITTKEPLESKTYVSVDSTTAAVLTGQSSTSVPLDQSSNTVLPSILITIAASDQSSTIAPNGGITTKDPLSSKTSVPNDSTTAQVLASQSSTTLSPGQSISGIPNDLSNTTADDSSVTTKEPLDSKTYVSVDSTTAAVPVGQSSTTVSPDQSSNIVLPSLLTTTTASDQSSTNAPNGPVTTKDPLSSKTSVPDDSIATVVPTELSSTPLSPGHPSNAVPNDLLSTTTNNGPITTKEPLEPKTYVSVDSTTAAVPVGQSSTTVPLEKSSNIVPPSLLTTTAASGQSSTKAPNGSITTKDPLSSKTSVPNDSTNATGPAGQSITTLSPGQSISGVPNDLSSTTADDSSVTTKEPLDSKTYVSVDSTTAAVPVGQSSTTVPLDQSSNVVLPSLLITTAASDQSSTNAPNGGITTKDPLSSKTSSLNDSTTAPVPAGQSSTTLSPGQSISGVPDDLSSTTANNNSVTTKEPLDLNTYVSVESTTAAVPEGQSSTTVSPDQSSNIVLPSLLTTTTASDQSSTNAPNGPVTTKDPLSSKTSVPDDSIATVVPTELSSTPLSPGQSISGVPNDLSSTTTNNGPITTKEPLEPKTYVSDDSSTAAVPVGQSSTTVPLDQSSNIVHPSLLTTTAASGQSSTKAPNGSISTKDPLSSKTSVPNDSTNATGPAGQSTTTLSPGQSISGVPNDLSNTTADDSSVTTKEPLDSKTYVSVDSTTAAVPVGQSSTTVSLDQSSNVVLPSLLTTTAASDQSSTNATNGPITTKDPLRSKTSVPDDSIATVVSTELSSTPLSPGRPSNAVPTDLLSTTADNGPVNTKEPLDSKTYVSVDSTTAAVPEGQTSITVPLDQSSNLVLSSLLTTSAASDQSSTNTSNSPITPKDPLSSKTSVPDDSTTAPVPAGHSSTTLSPNHSISGIPNDLSSTTTDNGPVTAKEPLDSKTSVPVNFTTAPVPTDLSITTLSSGHLNSGVPNDLSSTTTNNRPITTKETLEPKTYVSVDSTTAAVPVGQSSITVPLDQSSNIVPPSLLTTTAASGQSSTKAPNGSITTKDPLSSKTSVPNDSTNATGPAGQSTTTLSSGQPISGVPDDLSSTTADDNSVTTKEPLDSKTTVSVDSTTAAVPVGQSSTTVPLDQSSNVVLPSLLTTTPASDQSSTNATNGSITTKDPLSSKTTVPNDSATASVLAGQSTTTLSSGHSMSGVPNDLSSTTDKNGPVTTKETLDSSYTYVPIDSTTETVHKYESSTTVPLDHSSNLVFPSLLTTKAAFDQSRTTAPNGPFTIIDLLGSKTSVPVDSTTAAIPAYQSSTTVPLDQSSNVVLPSLLTTTAASDQLSITAPNSPITTKPLLSSKTSVPDDSTIAPFPTDLSSTTLSPGHSISGVPNYLSSTTASNGPVTTKDSLDSSYTTFPTEFKTTAVPDYGSSTKDPLDQSSNVLSITTANNGPLPTKDQSSNVVLNPLTATVPNVQSSTTGPNGPIITKDILGSSKSSVPDKFTTAAGPTDLSSTAPSPGHSNNAVPNDWSIATADNGPVMTKEPLYSKTSVLIDSTPVSVPADQSSTIVLLDQSSNVVHSSLLTAVASAQTDTTSPNSPMTSSKTLVPDNSITTADPTNLSITIVSLGHSSNAVPNDLSNTTANHGQVTTKETVDYSKTSLPVDSTTAAPPADKSSTTVFLDQSRNVVVSSLSTTTVSKDQPNTSASNGSQTTKDLLGSSKASVPDDSTTTVSTDLSSTTLSPGYPSIAVPNDLLSTTADNRPVTTKEPLDSKTSVLADSTTVVVLADQPSPTLLLDRSNNVVIHSLITTTVASDQSTTSALNNPVSSTAANRFTTTIIFATSAHSNIVTTSTTSSSPPTTYSSTKASTGSAMPGEVFVVLQIRLQTQYIDAYNNPASVEYQSLSRNITIELNRLYQSIYGTRFLRCYVIRFWPGSVGVDTQIIFQNQNVLPNATSIEETLSTAITDSNVFLPVIPSSITVVESLGSINTTSQTQTLQSVSTNQTSSAVAPVLSSVLFTLWLFLRNEIL", "length": 2680, "header": "tr|A0A8M9PDQ0-1|A0A8M9PDQ0_DANRE Isoform 1 of SEA domain-containing protein OS=Danio rerio OX=7955 GN=LOC101886224 PE=4 SV=3 CANONICAL=A0A8M9PDQ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101886224", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886224", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1094, "end_pos": 1096, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1130, "end_pos": 1132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1307, "end_pos": 1309, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1324, "end_pos": 1326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1328, "end_pos": 1330, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1355, "end_pos": 1357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1419, "end_pos": 1421, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1534, "end_pos": 1536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1573, "end_pos": 1575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1608, "end_pos": 1610, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1705, "end_pos": 1707, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1722, "end_pos": 1724, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1726, "end_pos": 1728, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1817, "end_pos": 1819, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1820, "end_pos": 1822, "annotation": "n_glycosylation_sequon" }, { "start_pos": 182, "end_pos": 184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1837, "end_pos": 1839, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2270, "end_pos": 2272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2291, "end_pos": 2293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2354, "end_pos": 2356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2359, "end_pos": 2361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2558, "end_pos": 2560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2604, "end_pos": 2606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2640, "end_pos": 2642, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2654, "end_pos": 2656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 749, "end_pos": 751, "annotation": "n_glycosylation_sequon" }, { "start_pos": 780, "end_pos": 782, "annotation": "n_glycosylation_sequon" }, { "start_pos": 962, "end_pos": 964, "annotation": "n_glycosylation_sequon" }, { "start_pos": 979, "end_pos": 981, "annotation": "n_glycosylation_sequon" }, { "start_pos": 983, "end_pos": 985, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PDQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDQ0" }, { "id": "PS50024", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50024" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SEA", "eco_id": "ECO_0000259", "start_pos": 2526, "end_pos": 2637, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1094, "end_pos": 1096 }, { "start_pos": 1130, "end_pos": 1132 }, { "start_pos": 1307, "end_pos": 1309 }, { "start_pos": 1324, "end_pos": 1326 }, { "start_pos": 1328, "end_pos": 1330 }, { "start_pos": 1355, "end_pos": 1357 }, { "start_pos": 1419, "end_pos": 1421 }, { "start_pos": 1534, "end_pos": 1536 }, { "start_pos": 1573, "end_pos": 1575 }, { "start_pos": 1608, "end_pos": 1610 }, { "start_pos": 1705, "end_pos": 1707 }, { "start_pos": 1722, "end_pos": 1724 }, { "start_pos": 1726, "end_pos": 1728 }, { "start_pos": 1817, "end_pos": 1819 }, { "start_pos": 1820, "end_pos": 1822 }, { "start_pos": 182, "end_pos": 184 }, { "start_pos": 1837, "end_pos": 1839 }, { "start_pos": 2270, "end_pos": 2272 }, { "start_pos": 2291, "end_pos": 2293 }, { "start_pos": 2354, "end_pos": 2356 }, { "start_pos": 2359, "end_pos": 2361 }, { "start_pos": 2558, "end_pos": 2560 }, { "start_pos": 2604, "end_pos": 2606 }, { "start_pos": 2640, "end_pos": 2642 }, { "start_pos": 2654, "end_pos": 2656 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 63, "end_pos": 65 }, { "start_pos": 749, "end_pos": 751 }, { "start_pos": 780, "end_pos": 782 }, { "start_pos": 962, "end_pos": 964 }, { "start_pos": 979, "end_pos": 981 }, { "start_pos": 983, "end_pos": 985 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PE61-1", "uniprot_ac": "A0A8M9PE61", "uniprot_id": "A0A8M9PE61_DANRE", "mass": { "chemical_mass": 204350.0, "monoisotopic_mass": 204350.0 }, "refseq": { "ac": "XP_021329407", "name": "PH-interacting protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329407" }, "gene_names": [ { "name": "phip", "type": "recommended", "evidence": [ { "id": "A0A8M9PE61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61" } ] }, { "name": "phip", "type": "synonym", "evidence": [ { "id": "XP_021329407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329407" } ] } ], "protein_names": [ { "name": "PH-interacting protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PE61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61/entry#names_and_taxonomy" } ] }, { "name": "IRS-1 PH domain-binding protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PE61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61/entry#names_and_taxonomy" } ] }, { "name": "PH-interacting protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021329407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329407" } ] }, { "name": "WD repeat-containing protein 11", "type": "synonym", "evidence": [ { "id": "A0A8M9PE61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021329407.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329407" } ] }, { "annotation": "Probable regulator of the insulin and insulin-like growth factor signaling pathways. Stimulates cell proliferation through regulation of cyclin transcription and has an anti-apoptotic activity through AKT1 phosphorylation and activation. Plays a role in the regulation of cell morphology and cytoskeletal organization.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE61", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61#function" }, { "database": "UniProtKB", "id": "ARBA00058276", "url": "https://www.uniprot.org/uniprotkb/ARBA00058276#function" }, { "database": "UniProtKB", "id": "A0A8M9PQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQW8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE61", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "phip", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050208-261", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-261", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05529", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05529", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "569727", "url": "https://www.ncbi.nlm.nih.gov/gene/569727", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569727", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569727", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR16266", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16266", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16266:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16266:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021329407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329407", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PE61", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PE61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQW8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IM31", "url": "https://www.uniprot.org/uniprotkb/A0AC58IM31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IM31-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IM31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050208-261", "url": "https://zfin.org/ZDB-GENE-050208-261", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAAERKHVAQLKSELYFLIARFLEAGPCQDAAETLIREVQQKELLPKRIDWTGKEHPGSYENLVKLYRHISPDHLLQVCERVSPLLEREVPASVPGVNSLLGTGRQSVLRTNKSCKHVVWKGSALAALHCGRPPEPPVIFGSPPNIAETIHSRRLNGSYRLGQLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGHLLATLRGHAAEISDMAVNYENTLLAAGSCDKMIRVWCLQTCAPLAVLEGHAASITSLQFSPLCSGNKRFLSSTGADGTICFWQWDARTLKFGQRPSKFIERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYYFGGGQPEKISELESHTDKVDSIQFSHSGDRFVSGSRDGTARIWQLQQQDWRSILLDMATKLPGKYNPPPLEDKVTKLKVTMVAWDCNDNTVITAANNLTLKVWNSYTGNLIHVLMGHEDEVFVLEPHPFDSRVLFSAGHDGNAIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSRYDKIADQMFFHTDYRPLIRDAHNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRFQRLVPGRENCREEQLIPQMGLTSSGLNQVVSQQAAEGSSPLDSMIQRLQQEQDQRLGSDSRANRGSVSSPTEVTSPPNVGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVLVPELSLAIACKQEIWRTAKGEEEINIYRSERRRRSLHSQYHRENRHAIENAAEEGRRHQGNQHNYHTRLAVEETSRQSEPNEEEHSASEGETEVRPPSRESSDEEREEKEPWPDENSSSSDYSSDYSDWTADAGINLEPPKKTSVKKKKKKNASSSEEDGEKKKDSKKERRKEKPDKDGALPKKKKPKEKRKRIPELQNQGLTLEEWLPSNWITDTMPRRCPFTPQMGDEVYYFRQGHEAYVEMAKKNKIFSINPKKQPWHKLELREQELLKIVGIKYEVGLPTLCCLKLAFLDPDSGKLTGGSFSIKYHDMPDVIDFLVLRQQFDNARQRNWMIGDRFRAVIDDAWWFGTIESQEPYQAEYPDSLFQCYNVCWDNGDTEKMSPWDMEEVPDEVVFPEELGLSMALTQDEQKALLYKPLDGEWGSRTRNQECERIIRGINQLCTLDVAKPFELPVDLQAYPTYCTVVAYVTDLSTIRQRLENRFYRRMSSLMWEVRYIEHNAQTFNEPGAFIVRTAKFVSDLMLQFIKDQSCTDIIPLYNSMKKTAFSDSSDDEDEDEDEEHEAPCTSNRNKKRQQQQPMLRSLRSKPSSDPQAWKERCRELLELIFQCEDSEPFRQPVDLDEYPDYLDIVDTPMDFGTVLNRLLAGEYDTPMDLCKDVRLIFSNSKAYTPSKKSRIYSMSLRLSALFEEHISSILTDFKAAQSLHSERLTRQRLHTDRLTRQSVKKRRRRSSSHSSSASSPERKRRVSSRAPPRLDSAAPPTPAGPSRAPSLRQTHPQINGKAETPVVPGRTRSSARFGSPITDVAPAQSAPPPLVESSSSRVLRTQNPHSTAVSRENESSAVPPSNGGGARESRRKLRTPVKLTPGPVDHSSPPQNSLHLNGHSQVTVGMVRRGRGRPRLDTQIETPVDTPPPPLPKTSSKKKERKSKKDTESPRRNFSHEEELMLPTGDDGGASSTAQDSNLSDSGEYPKARGRPRITKTIDTPAPPSPKTLRRSSRRGNEEITPHTSGSAQSEEPEVYIGEDGSSKGQMKTRNQGRRTAFYNEEDSEEEQRQLLFEDASITFGTSSKGRVRKLTEKAKANLIGW", "length": 1807, "header": "tr|A0A8M9PE61-1|A0A8M9PE61_DANRE Isoform 1 of PH-interacting protein OS=Danio rerio OX=7955 GN=phip PE=4 SV=2 CANONICAL=A0A8M9PE61-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PE61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61/entry#A0A8M9PE61-1", "sequence": { "sequence": "MAAERKHVAQLKSELYFLIARFLEAGPCQDAAETLIREVQQKELLPKRIDWTGKEHPGSYENLVKLYRHISPDHLLQVCERVSPLLEREVPASVPGVNSLLGTGRQSVLRTNKSCKHVVWKGSALAALHCGRPPEPPVIFGSPPNIAETIHSRRLNGSYRLGQLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGHLLATLRGHAAEISDMAVNYENTLLAAGSCDKMIRVWCLQTCAPLAVLEGHAASITSLQFSPLCSGNKRFLSSTGADGTICFWQWDARTLKFGQRPSKFIERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYYFGGGQPEKISELESHTDKVDSIQFSHSGDRFVSGSRDGTARIWQLQQQDWRSILLDMATKLPGKYNPPPLEDKVTKLKVTMVAWDCNDNTVITAANNLTLKVWNSYTGNLIHVLMGHEDEVFVLEPHPFDSRVLFSAGHDGNAIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSRYDKIADQMFFHTDYRPLIRDAHNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRFQRLVPGRENCREEQLIPQMGLTSSGLNQVVSQQAAEGSSPLDSMIQRLQQEQDQRLGSDSRANRGSVSSPTEVTSPPNVGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVLVPELSLAIACKQEIWRTAKGEEEINIYRSERRRRSLHSQYHRENRHAIENAAEEGRRHQGNQHNYHTRLAVEETSRQSEPNEEEHSASEGETEVRPPSRESSDEEREEKEPWPDENSSSSDYSSDYSDWTADAGINLEPPKKTSVKKKKKKNASSSEEDGEKKKDSKKERRKEKPDKDGALPKKKKPKEKRKRIPELQNQGLTLEEWLPSNWITDTMPRRCPFTPQMGDEVYYFRQGHEAYVEMAKKNKIFSINPKKQPWHKLELREQELLKIVGIKYEVGLPTLCCLKLAFLDPDSGKLTGGSFSIKYHDMPDVIDFLVLRQQFDNARQRNWMIGDRFRAVIDDAWWFGTIESQEPYQAEYPDSLFQCYNVCWDNGDTEKMSPWDMEEVPDEVVFPEELGLSMALTQDEQKALLYKPLDGEWGSRTRNQECERIIRGINQLCTLDVAKPFELPVDLQAYPTYCTVVAYVTDLSTIRQRLENRFYRRMSSLMWEVRYIEHNAQTFNEPGAFIVRTAKFVSDLMLQFIKDQSCTDIIPLYNSMKKTAFSDSSDDEDEDEDEEHEAPCTSNRNKKRQQQQPMLRSLRSKPSSDPQAWKERCRELLELIFQCEDSEPFRQPVDLDEYPDYLDIVDTPMDFGTVLNRLLAGEYDTPMDLCKDVRLIFSNSKAYTPSKKSRIYSMSLRLSALFEEHISSILTDFKAAQSLHSERLTRQRLHTDRLTRQSVKKRRRRSSSHSSSASSPERKRRVSSRAPPRLDSAAPPTPAGPSRAPSLRQTHPQINGKAETPVVPGRTRSSARFGSPITDVAPAQSAPPPLVESSSSRVLRTQNPHSTAVSRENESSAVPPSNGGGARESRRKLRTPVKLTPGPVDHSSPPQNSLHLNGHSQVTVGMVRRGRGRPRLDTQIETPVDTPPPPLPKTSSKKKERKSKKDTESPRRNFSHEEELMLPTGDDGGASSTAQDSNLSDSGEYPKARGRPRITKTIDTPAPPSPKTLRRSSRRGNEEITPHTSGSAQSEEPEVYIGEDGSSKGQMKTRNQGRRTAFYNEEDSEEEQRQLLFEDASITFGTSSKGRVRKLTEKAKANLIGW", "length": 1807, "header": "tr|A0A8M9PE61-1|A0A8M9PE61_DANRE Isoform 1 of PH-interacting protein OS=Danio rerio OX=7955 GN=phip PE=4 SV=2 CANONICAL=A0A8M9PE61-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PQW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61/entry#A0A8M9PQW8-1", "sequence": { "sequence": "MAAERKHVAQLKSELYFLIARFLEAGPCQDAAETLIREVQQKELLPKRIDWTGKEHPGSYENLVKLYRHISPDHLLQVCERVSPLLEREVPASVPGVNSLLGTGRQSVLRTNKSCKHVVWKGSALAALHCGRPPEPPVIFGSPPNIAETIHSRRLNGSYRLGQLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGHLLATLRGHAAEISDMAVNYENTLLAAGSCDKMIRVWCLQTCAPLAVLEGHAASITSLQFSPLCSGNKRFLSSTGADGTICFWQWDARTLKFGQRPSKFIERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYYFGGGQPEKISELESHTDKVDSIQFSHSGDRFVSGSRDGTARIWQLQQQDWRSILLDMATKLPGKYNPPPLEDKVTKLKVTMVAWDCNDNTVITAANNLTLKVWNSYTGNLIHVLMGHEDEVFVLEPHPFDSRVLFSAGHDGNAIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSRYDKIADQMFFHTDYRPLIRDAHNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRFQRLVPGRENCREEQLIPQMGLTSSGLNQVVSQQAAEGSSPLDSMIQRLQQEQDQRLGSDSRANRGSVSSPTEVTSPPNVGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVLVPELSLAIACKQEIWRTAKGEEEINIYRSERRRRSLHSQYHRENRHAIENAAEEGRRHQGNQHNYHTRLAVEETSRQSEPNEEEHSASEGETEVRPPSRESSDEEREEKEPWPDENSSSSDYSSDYSDWTADAGINLEPPKKTSVKKKKKKNASSSEEDGEKKKDSKKERRKEKPDKDGALPKKKKPKEKRKRIPELQNQGLTLEEWLPSNWITDTMPRRCPFTPQMGDEVYYFRQGHEAYVEMAKKNKIFSINPKKQPWHKLELREQELLKIVGIKYEVGLPTLCCLKLAFLDPDSGKLTGGSFSIKYHDMPDVIDFLVLRQQFDNARQRNWMIGDRFRAVIDDAWWFGTIESQEPYQAEYPDSLFQCYNVCWDNGDTEKMSPWDMEEVPDEVFPEELGLSMALTQDEQKALLYKPLDGEWGSRTRNQECERIIRGINQLCTLDVAKPFELPVDLQAYPTYCTVVAYVTDLSTIRQRLENRFYRRMSSLMWEVRYIEHNAQTFNEPGAFIVRTAKFVSDLMLQFIKDQSCTDIIPLYNSMKKTAFSDSSDDEDEDEDEEHEAPCTSNRNKKRQQQQPMLRSLRSKPSSDPQAWKERCRELLELIFQCEDSEPFRQPVDLDEYPDYLDIVDTPMDFGTVLNRLLAGEYDTPMDLCKDVRLIFSNSKAYTPSKKSRIYSMSLRLSALFEEHISSILTDFKAAQSLHSERLTRQRLHTDRLTRQSVKKRRRRSSSHSSSASSPERKRRVSSRAPPRLDSAAPPTPAGPSRAPSLRQTHPQINGKAETPVVPGRTRSSARFGSPITDVAPAQSAPPPLVESSSSRVLRTQNPHSTAVSRENESSAVPPSNGGGARESRRKLRTPVKLTPGPVDHSSPPQNSLHLNGHSQVTVGMVRRGRGRPRLDTQIETPVDTPPPPLPKTSSKKKERKSKKDTESPRRNFSHEEELMLPTGDDGGASSTAQDSNLSDSGEYPKARGRPRITKTIDTPAPPSPKTLRRSSRRGNEEITPHTSGSAQSEEPEVYIGEDGSSKGQMKTRNQGRRTAFYNEEDSEEEQRQLLFEDASITFGTSSKGRVRKLTEKAKANLIGW", "length": 1806, "header": "tr|A0A8M9PQW8-1|A0A8M9PQW8_DANRE Computationally mapped isoform of PH-interacting protein OS=Danio rerio OX=7955 GN=phip PE=4 SV=2 CANONICAL=A0A8M9PE61-1" }, "locus": {} }, { "isoform_ac": "A0AC58IM31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61/entry#A0AC58IM31-1", "sequence": { "sequence": "MKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGHLLATLRGHAAEISDMAVNYENTLLAAGSCDKMIRVWCLQTCAPLAVLEGHAASITSLQFSPLCSGNKRFLSSTGADGTICFWQWDARTLKFGQRPSKFIERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYYFGGGQPEKISELESHTDKVDSIQFSHSGDRFVSGSRDGTARIWQLQQQDWRSILLDMATKLPGKYNPPPLEDKVTKLKVTMVAWDCNDNTVITAANNLTLKVWNSYTGNLIHVLMGHEDEVFVLEPHPFDSRVLFSAGHDGNAIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSRYDKIADQMFFHTDYRPLIRDAHNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRFQRLVPGRENCREEQLIPQMGLTSSGLNQVVSQQAAEGSSPLDSMIQRLQQEQDQRLGSDSRANRGSVSSPTEVTSPPNVGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVLVPELSLAIACKQEIWRTAKGEEEINIYRSERRRRSLHSQYHRENRHAIENAAEEGRRHQGNQHNYHTRLAVEETSRQSEPNEEEHSASEGETEVRPPSRESSDEEREEKEPWPDENSSSSDYSSDYSDWTADAGINLEPPKKTSVKKKKKKNASSSEEDGEKKKDSKKERRKEKPDKDGALPKKKKPKEKRKRIPELQNQGLTLEEWLPSNWITDTMPRRCPFTPQMGDEVYYFRQGHEAYVEMAKKNKIFSINPKKQPWHKLELREQELLKIVGIKYEVGLPTLCCLKLAFLDPDSGKLTGGSFSIKYHDMPDVIDFLVLRQQFDNARQRNWMIGDRFRAVIDDAWWFGTIESQEPYQAEYPDSLFQCYNVCWDNGDTEKMSPWDMEEVPDEVVFPEELGLSMALTQDEQKALLYKPLDGEWGSRTRNQECERIIRGINQLCTLDVAKPFELPVDLQAYPTYCTVVAYVTDLSTIRQRLENRFYRRMSSLMWEVRYIEHNAQTFNEPGAFIVRTAKFVSDLMLQFIKDQSCTDIIPLYNSMKKTAFSDSSDDEDEDEDEEHEAPCTSNRNKKRQQQQPMLRSLRSKPSSDPQAWKERCRELLELIFQCEDSEPFRQPVDLDEYPDYLDIVDTPMDFGTVLNRLLAGEYDTPMDLCKDVRLIFSNSKAYTPSKKSRIYSMSLRLSALFEEHISSILTDFKAAQSLHSERLTRQRLHTDRLTRQSVKKRRRRSSSHSSSASSPERKRRVSSRAPPRLDSAAPPTPAGPSRAPSLRQTHPQINGKAETPVVPGRTRSSARFGSPITDVAPAQSAPPPLVESSSSRVLRTQNPHSTAVSRENESSAVPPSNGGGARESRRKLRTPVKLTPGPVDHSSPPQNSLHLNGHSQVTVGMVRRGRGRPRLDTQIETPVDTPPPPLPKTSSKKKERKSKKDTESPRRNFSHEEELMLPTGDDGGASSTAQDSNLSDSGEYPKARGRPRITKTIDTPAPPSPKTLRRSSRRGNEEITPHTSGSAQSEEPEVYIGEDGSSKGQMKTRNQGRRTAFYNEEDSEEEQRQLLFEDASITFGTSSKGRVRKLTEKAKANLIGW", "length": 1635, "header": "tr|A0AC58IM31-1|A0AC58IM31_DANRE Computationally mapped isoform of PH-interacting protein isoform X3 OS=Danio rerio OX=7955 GN=phip PE=4 SV=1 CANONICAL=A0A8M9PE61-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:569727", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569727", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZZE0-1", "protein_name": "Bromodomain and WD repeat-containing protein 3", "gene_name": "Brwd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKNTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMSGNNLTSTEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQEESILDGIIRELQREQDLRLINEGDVPHFPINRSYSVNGALSSPNMDIPSSPNIGLRRSGQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKKPSYPIQRNDYQPSCGRSLRRTQRKRQHTYLTRSNIEHNSQASSQNSGVQGDSDSSSEEDETVGTSDASAEDPVVEWQSESSSSDSSSEYSDWTADAGINLQPPKRQTRQATQKIYSSSEDENVKSSEDRQKKPKQTRKKKGGLVSMAGEPNEEWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDTYNKIKAENPNSSDPEEDTEMVDLDSDGPGTSSGRRAKCRGRRQSLKCNPDAWKQQCKELLSLIYEREDSEPFRQPADPHSHPAQQQEGESSESVPPDRQDPSLSEDYQDVVDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENRIKNIISEYKSAIQSQKRRRPRYRKRLRSSSSSLSSSRAPSPKGKQKQMKLQPKNDQNTSVVYARTSSPFSSPVSDAAEGVSLYLLDDEGDGPFSPSSCSGYSRSGNSHDPGKAKSFRNRVLPAKQDHSLDGPLTNVDGREPRTGAKRKLLSASEEDESMGGEEKEMKETKEKAHLSSSESGELGSSLSSESTSGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRRQHATGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGGRGRGGGGGRGRGRGRGGRGASRGASRTKRARVADDEFDTMFAGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1799 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1QKF7-1", "protein_name": "Bromodomain and WD repeat-containing protein 3", "gene_name": "brwd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADTTARNGSISPLESELYYLISRYLSTGPCRKAAEALVCELEENQLLPRRLDWEGNEHPRSYEDLVTANRHIAPDHLLQICKQIGPVLDREVPSGVPGVHSLLGAGRHSLLRTSKDCCASRWKTSTFAALHRGRPPERPLNCKDANIVEVCRGRELTGAQRFSSINPVSNYQHMKMHRRILGHLSAVYCIAFDRTGSRIFTGSDDALVKIWSSFDGRLHSTLRGHYAEISDLAVNFENTLIAAGSCDKTIRVWCLRTCAPVAVLQGHSGSITSLQFSPFVKGSKRYMVSTGTDATVCFWQWDVNNNEFSDRQHKFTERPRPGVQTVCSSFSPGGMFLATGSTDDVIRIYYLGSGSPEKLAELDSHTDKVDSIQFCHSGERFVSGSRDGTARIWRLHQRHQWKSVLLDMSATLPGSAPLTDDENFFKPKVTMVSWDRHDNTVITAVNNHLLKVWNSYTGQLLHVLKGHEAEVFVLEPHPYDPRIMLSAGHDGNVFVWDLIKGTKTMHYFNMIEGQGHGAVFDCKFTPDGHRFAMTDSHGHLVIFGFGSSKPYEKLPDQVFFHTDYRPLIRDTNGFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRFQRLVPGRENIADEHLVPQLGYVATSDGEVVEQVISQQSAESEEVRHSALDFAIRQLREHQDRQSGAPGEAGVPAAARVPEPGTPRRVSVNERMEVQSPPNVGLRRSGQVEGVRQMHQNAPRSQMATERDLQAWRRRVVIPELTPSGYRAQESFRIAKGDEEVNLYNTKKRRVTHSTFRDDSDEEGPCLKRTQSRKRQKNQERKENLAEEYIEFSCEEGEETASSEASEVEGSDIDSSAEDEEEWKSDSSSRSSSDYSDWTADAGISVRTSDSSRRRTTRRISSSEEEDEEDDEEEEEPADEEPAVGEEETSSPRKHKKAKSKTPKHSKPRPSINREISNEFRPPAWITDVVPRKSPFVPQMGDEVIYFRQGHEAYVDAVCRMNLYPINLDKQPWKKMQLRDQEFVKITGIKYEVCPPTLCCLKLTQIDPGTGKITDRTFSIKYHDMADVIDFLVLRQSYDEARNRVWTSNDRFRSVIDDAWWFGAIVCHEPYQSEYPDSHFQCFKVKWDNGETEKLSPWDVEAIPENAEQPESASAGVPVTDEEMMDILYKPQRGEWGDRGREQESARIIAGIEQLMTVDITAPFSGPVDLTQYPTYCTVIAYPTDLNTIKLRLKHNFYRRLSALIWDVKHIEQNAKTFNEPRSKIAQSAKIITNVLIKFISKLHCTDIMEIYNAVENMEYSDDEEMDDIDAPGTSAGQRLRQPSVEVVLDRDAWKDHCKRLLDYMFECEDSEPFRDPVDQSDYPDYTNIIDTPMDLGTVRQTLEEDRYENPIDVCKDIRLIFANAKAYTPNKRSKIYSMTLRLSAFFEENIRKIISDYKTAIKSSLKLRRSQRCRKKSQHQESVSFSQGSTRQKRATIKTQENTEQSTAKSTSAKVSGPERRRAHEAKETFRRSSSSSSGSDQDSKQSLSQSDEDDEHSSSSRAMRRETRATRKKAAQNKGAKSRRPESHVKMNGRSRSHERQKPRTSSDSDHEPSQGSDEASENESSPSVSRRPRTRKTAMAAVNKMKLIDTLGDEEGTDDEGGGGSTRPATRASKRSAVIQSSSDSDDEEEAAASQEESNESGSSASEGEKSAGSADSDSSSHSKKNSRTAGRRPCRRPAEKKETSPLTNGHGTKRQWEESDDNSEDGGSPIESENLESDNDLVVRRKSTRRTAKAAVSKIKKINNTDAEEEENCTRDRRQKHRSITQESENSSDEEVETTKTLKHPHQNGRKVDAKELKRCKAPSERQEQSPAAKQKTTHKKSSATDACMSTTQDSEELSDDVEKSVTHRKRIASEDEENQSDDADQRRVPKNRNRSSNARKQKLCASSDESSSESDEKADRGRIKSEGTSSDEWQKSDTSEEDKKTHPQRKPCPTVASKGVSLRTRPKKNYIMEDSEEEFSPKMDVQAKNGVKNQQANSRTRKPSGGGFKRKHGGSSESDADSKSSRSSDGNKLAEAQRKSAKRFKQLMGSTDSESDFETRCKSENGRAQRSQGKLPTVSRQRRKQSESDKGSNDNGSNFESEESESEASSGSRSSPKRRLRDRDRGTARSRKPRRVVSDDDSDVSFEKPRRGRRIQTRNKGKRTVNYQDSE", "length": 2182 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PQW9-1", "protein_name": "Bromodomain and WD repeat-containing protein 3 isoform X1", "gene_name": "brwd3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAEPCSQIEAELYYLIARFLQSGPCQKSAQMLLQELHEYEIIPKRWSCDGEQFKRSFDDWVLLNQHIPADYLLRVCKQVGPLIDKHIPPSVPGVHSLLGTGRQSLLRTAKSSSHTLWSGSAVAALHRGRPPEPPISCAKSPNIVSIIGARQKTGVARFGHAFPSCAYQHMKMHRRILGHLSSVYCVAFDRTGRRIFTGSDDCLVKIWATDNGRLLATLRGHAAEISDMTVNFENTLLASASCDKIVRVWCLRTCAPVAVLQGHTASITSIQFSPSALGSSRFLATTGADGMVCFWQWNSFSMKFVDKPVKFMERSRPGVQISCSSFSSGGLFLATGGTDHMIRVYYLGTEMPVKFSDLDSHTDKVVAIQFCNNTDSLRFVSGSRDGTARIWHYQQQEWKSTVLDMTTRLPGSAVISGDDKSTKLVVTMVAWDRCDRSIITAVSNCLLKVWNSTNGQLLHVLLGHDDEVFVLEAHPFDSRILLSAGHDGNIYVWDLSKGQKIRNFFNMIEGQGHGAVFDCKFSVDGQHFACTDSHGHLLIFGFGCSQPYEMIPDQMFFHTDFRPLIRDSNNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRCQRLVPGRENCKEEQLVPQLGYMANGDGEVVEQVIGQQTADESQEESPLDDLIRQLQNQQDERVNQANPAGAEVAGGPLSPPNVGLRRSGQVEGVRQMHNNAPRSQMATERDLLAWSRRVVVNEVQAGIFRVMEDCRLAKGEVERSYYIIEKKRKSVPSTGSQPGDNVRTLRRPQRKAQQKRHAYQTRSTRTRRRSGSVQSFSRNEETEVESESEAEQEEDQNENSDGTSEGETQWENDSSSSDSSSEYSDWTADAGINLQPPKRTTRRPARVAVSSSSEDEEGTGQGEGEAAQTTKQAEKKKKPKQRSVPAGELEEWLPPSWIMETIPRRSPFVPQMGDELIYFRQGHQAYVRAVSRAKAYSINPQKQPWNRLNLRDQESVKVVGIKYEVGPPTLCCLKLAILDLTSGKMTNESFSLKYHDMPDVIDFLVLQQFYNEAKERNWQPGQRFRSIIDDAWWFGSLECQEPFESEYPDSLFQCYIVRWDNGEREKMSPWDIEPIPEEAPLPEEDGDSVPVTEDELQALLYSPQEGEWGLHTRDEECERVITAIDQLLTLDVAKAFSNPVNLREYPLYCTVVAYLTDLSTIRTRLVHRFYRRISALMWEVRYIEHNARTFNEPQSPIVTAAKTVSDVLLRFIRDQNCTDILDLYNKMKSEFSSEEDEEETVDVDSDTPGTSTGQRRSNSTPQKRGVVLDINAWHKQCKDLVRRMIVSSDSEPFRQPVDLFTYPDYRDIIDTPMDLGTVSETLTGGNYENPIEFAKDVRLIFSNSKAYTPNKKSRIYSMTLSLSAFFENQIIPIISDYKSAVQNQRRSQQRLMCSKRLQSSSPNSPKGKQKSGKKTLQMSAKARTRKSSQDSNVAQVDEDSQPSSSSSSSSSSSSSSSFSSEQAGANRVTRSQVTSSKSSGVFLPNGGRSSRRRRAVLTEEGEVSECESTSSSSSSTSASSSSSATSSSSSESDDSSAEVSGFADGGDHDYSKAPQHKQKGKAPAPPPPPSPPPPAPTIDNPKRKRKGEEEQSAEPEKRPRRTSSREEEEEEEEEEVDDEPEEEEEPDEEEEPEEEEEESDDENVISPSKRSNQRTPKSGRVNTRNQGRRTVLYNDDSEEEGPTSDPLNLGMSRSGRVRRMTERARVSHLMGWTH", "length": 1741 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LKM2-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "Brwd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEAPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGPPPSLVDIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWKSILLDMAARISGDTSAEEERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENSADEHLVPQLGYVATSDGEVIEQVISLHTNDSGDASPESSVLDGMIRQLQQQQDLRLGVDQDVTANGLPNEEGTPRRGSFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQIATERDLQAWKRRVVVPEAPPGVFRRLEDIRIERGEEERNLYVIGRKKKTFQLPQKSNSMVLVSQSRQRTCRRKYANYSRRNAGQCELSSGNESSGSVRHETSCDQSEGSCSSEDDEWRSDRRSGSDSDSPSESSSQYSDWTADTGVHLEPPLRTSCRRRVTRFCSTSEDEMSTENISPPKRRRKRRKESKPKRESLRRTTPAELANMEPLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPSDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYSVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQDGEWGQRSRDEECERIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVHRFYRRLSALIWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQDCTNILELCNTSDSDGDSADDLDDSDLPKTSSGRRRVHNWKRRSRGSSCIESDWRRQCKALLILIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLEAGNYDSPVEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISFDFKIGQKFKEKLRRSQRFKQRQKCNGAVPVDRSMRSVKQKQFRSQTKVIPQLMCSPSQSTSSKVPLSATRKTSAGVSSGCTSGDSSDSAGSLERVRRHRAETLRSGSVLFGSEMEDFLATSSSSSSSNSSDESKESSGAQECSLRSGVLRSSNLRVTRTRAARRKAGSVSLENGCGRKATRKRVYLSDSDNHSVETDENLKSKAGSSRKVLRKCAAVAASKIKLMSDAEDSSSESPCSGRKLPHRNASAVARKKLLHNSDDQSLKSETEEVRDRNQALLMSSPHAVQNCISDSESDSDLQAARKTWHANGCTSHPAAACKAKSRPIESSEEDSRCHESDHGPSSTVDPLTSGQKLGADSISEEADSEPGSSALGKNTHLSKKAKILSDSEDCEEKYGERRGPEVEGSPVSEALREAVIVPQCLSHHGPETDVDSDGSAVREKSHSNVNDSVSRENGQRKKVSRKRFCSSDSESNLQVIQKSPIDQTSPSRITRSAGMVTDKTKLTSDAEDVSLESVCTRSKRRRKKPVRFACTTAKSIPSSEGKHARCEVPEEQSACRSSLAEPEQQGSAENASQAANADLDFEGSSSFEQTKSIQKRQMDSVCIRAPSKTQNSSAGPSQEDPKSHTQDSDISLSSESVLAQKAIGENNFEEELNYGLRRWNGRRLRTYGKAPLSRTAPVTPSLQAAAEVRVKRRRVHPEVDGEDIPGQMGSSGCGPDTSPKSSDLGSVTESDVDCTDNTKAQRRKKRKGKTRVLSQESVRKDREPHTKTRPCMFNEKEAVQMHSDTLKPKTVPEKIPRRCAAIAANKIKTMCNLKEVVSGPENVGIRTNSRKLPYRQASAAAKKKLLSVYKEDDALIHSENEEEVYLRRFRSQKEKAQQSP", "length": 2303 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2AHJ4-1", "protein_name": "Bromodomain and WD repeat-containing protein 3", "gene_name": "Brwd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMSGNNLTSAEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQEESILDGIIRELQREQDLRLINEGDVPHFPINRSYSVNGALSSPNMDIPSSPNIGLRRSGQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKKPSYPIQRNDYQPSCGRSLRRTQRKRQHTYLTRSNIEHNSQASSQTSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSESSSSDSSSEYSDWIADAGINLQPPKRQTRQATQKIYSSSEDENLKLEDRQKKPKQTKKKKGGLVSMAGEPNEEWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPDGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCSDILDTYNKIKAEDPDSSDLEEDSEMVDLDSDGPGTSSGRRAKCRGRRQSLKCNPDAWKKQCEELLSLIYEREDSEPFRQPADPQSYPVQQQQEGESSQSVPPDRQDPSLSEDYQDGIDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENHIKNIISDYKSAIQSQKRRRPRYRKRLRSSSSSLSSSRAPSPKGKQKQMKLQPKNDQNTSVAYARTSSPFSSPVSDAAEGVSLYLLDDEGDGPFSPSSFSGYSRSGNSHDPGKAKSFRNRVLPAKQDHSLDGPLTNVDGREPRTGAKRKLLSASEEDESMGGEEKEMKETKEQVHLSSSESGELGSSLSSESTSGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRKQHTNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGGRGRGGGGGRGRGRGRGGRGASRGSSRAKRARVADDEFDTMFSGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1799 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M3B3-1", "protein_name": "PH-interacting protein", "gene_name": "Phip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPNIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPTKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDSTVITAVNNMTLKVWNSYTGQLIHVLTGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKVRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLVIFGFGSSSKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIPQMGVTSSGLNQVLSQQAIQDISPLDSMIQRLQQEQDLRRSGEAAVSSAGRLNRGSVSSTSEVHSPPNVGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKSYRSEEKRKHLTVAKENKILTVSKNHAHEHFLDLGDSKKQQANQHNYRTRSALEETPRPLEEIENGTSSSDEGEVLAVSGGTSEEEERAWHSDGSSSDYSSDYSDWTADAGINLQPPKKVPKHKTKKQDSSSDEEEESENQKQKHIKKERKKANEEKDGPTSPKKKKPKERKQKRLAVGELTENGLTLEEWLPSAWITDTLPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNRIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRRWNIGDRFRSVIDDAWWFGTIESQEPLQPEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDVECRSLIYKPLDGEWGANPRDEECERIVGGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRFSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIKHQHFLLFRDQTCYNIIPLYNSMKKKVLSDSEEEEKDADVPGTSTRKRKDHQPRRRLRNRAQSYDIQAWRKQCQELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTITKRRKRRNRSSSLSSSAASSPERKKRILKPQLKSEISTSPFSIPTRSVLPRHSAAQMNGKPESSSVVRTRSNRIAVDPVVTEQPSTSAATKAFVSKTNTSAMPGKTILENSVKHSKALSTLSSPDQLTFSHGTKNNSAKENMEKEKPVKRKMKSSVFTKASPLPKSSAVVDQGDCKNNVLIPGTIQVNGHGGQPSKLVKRGPGRKPKVEVNTSSGEVTHKKRGRKPKNLQCTTKQENSEQNNMHPIRGDVVPSSTCSFLSETNVVKEDLLQKKSRGGRKPKRKMKTQNLDSELIVPTNVKILRRSNRKKADDPIDEEEEFEELKGSEPHMRTRNQGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAKANLIGW", "length": 1830 }, "evidence": [ { "id": "HGNC:15673", "url": "https://alliancegenome.org/gene/HGNC:15673#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-261", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-261#orthology", "database": "AGR" }, { "id": "MGI:1932404", "url": "https://alliancegenome.org/gene/MGI:1932404#orthology", "database": "AGR" }, { "id": "RGD:1564964", "url": "https://alliancegenome.org/gene/RGD:1564964#orthology", "database": "AGR" }, { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6RI45-1", "protein_name": "Bromodomain and WD repeat-containing protein 3", "gene_name": "BRWD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQDESILDGIIRELQREQDLRLINEGDVPHLPVNRAYSVNGALRSPNMDISSSPNIRLRRHSSQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNNGVSRVQEECRTAKGDIEISLYTVEKKKKPSYTTQRNDYEPSCGRSLRRTQRKRQHTYQTRSNIEHNSQASCQNSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSESSSSDSSSEYSDWTADAGINLQPPKRQTRQTTRKICSSSDEENLKSLEERQKKPKQTRKKKGGLVSIAGEPNEEWFAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEVGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGVPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINHLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIRRRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDTYNKIKAEERNSTDAEEDTEIVDLDSDGPGTSSGRKVKCRGRRQSLKCNPDAWKKQCKELLSLIYEREDSEPFRQPADLLSYPGHQEQEGESSESVVPERQQDSSLSEDYQDVIDTPVDFSTVKETLEAGNYGSPLEFYKDVRQIFNNSKAYTSNKKSRIYSMMLRLSALFESHIKNIISEYKSAIQSQKRRRPRYRKRLRSSSSSLSSSGAPSPKGKQKQMKLQPKNDQNTSVSHARTSSPFSSPVSDAAEGLSLYLLDDEPDGPFSSSSFGGYSRSGNSHDPGKAKSFRNRVLPVKQDHSLDGPLTNGDGREPRTGIKRKLLSASEEDENMGGEDKEKKETKEKSHLSTSESGELGSSLSSESTCGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRKQHGNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGSRGRGGGGTRGRGRGRGGRGASRGATRAKRARIADDEFDTMFSGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1802 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VDD9-1", "protein_name": "PH-interacting protein", "gene_name": "Phip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPTKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKVRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIPQMGVTSSGLNQVLSQQANQDISPLDSMIQRLQQEQDLRRSGEAGVSNASRVNRGSVSSTSEVHSPPNIGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKSYRSEEKRKHLTVAKENKILTVSKNHAHEHFLDLGDSKKQQANQHNYRTRSALEETPRPLEELENGTSSSDEGEVLAVSGGTSEEEERAWHSDGSSSDYSSDYSDWTADAGINLQPPKKVPKHKTKKPESSSDEEEESENQKQKHIKKERKKANEEKDGPTSPKKKKPKERKQKRLAVGELTENGLTLEEWLPSAWITDTLPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRPWNIGDRFRSVIDDAWWFGTIESQEPLQPEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDVECRSLIYKPLDGEWGANPRDEECERIVGGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRFSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEEEEKDADVPGTSTRKRKDHQPRRRLRNRAQSYDIQAWKKQCQELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNFKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTISKKRKKRNRSSSLSSSAASSPERKKRILKPQLKSEVSTSPFSIPTRSVLPRHNAAQMNGKPESSSVVRTRSNRVAVDPVVTEQPSTSSATKAFVSKTNTSAMPGKAMLENSVRHSKALSTLSSPDPLTFSHATKNNSAKENMEKEKPVKRKMKSSVFSKASPLPKSAAVIEQGECKNNVLIPGTIQVNGHGGQPSKLVKRGPGRKPKVEVNTSSGEVTHKKRGRKPKNLQCAKQENSEQNNMHPIRADVLPSSTCNFLSETNAVKEDLLQKKSRGGRKPKRKMKTHNLDSELIVPTNVKVLRRSNRKKTDDPIDEEEEFEELKGSEPHMRTRNQGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAKANLIGW", "length": 1821 }, "evidence": [ { "id": "HGNC:15673", "url": "https://alliancegenome.org/gene/HGNC:15673#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-261", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-261#orthology", "database": "AGR" }, { "id": "MGI:1932404", "url": "https://alliancegenome.org/gene/MGI:1932404#orthology", "database": "AGR" }, { "id": "RGD:1564964", "url": "https://alliancegenome.org/gene/RGD:1564964#orthology", "database": "AGR" }, { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WWQ0-1", "protein_name": "PH-interacting protein", "gene_name": "PHIP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSCERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIPQMGVTSSGLNQVLSQQANQEISPLDSMIQRLQQEQDLRRSGEAVISNTSRLSRGSISSTSEVHSPPNVGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKTYRSEEKRKHLTVPKENKIPTVSKNHAHEHFLDLGESKKQQTNQHNYRTRSALEETPRPSEEIENGSSSSDEGEVVAVSGGTSEEEERAWHSDGSSSDYSSDYSDWTADAGINLQPPKKVPKNKTKKAESSSDEEEESEKQKQKQIKKEKKKVNEEKDGPISPKKKKPKERKQKRLAVGELTENGLTLEEWLPSTWITDTIPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRRWNIGDRFRSVIDDAWWFGTIESQEPLQLEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDGECRSLIYKPLDGEWGTNPRDEECERIVAGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEEKDADVPGTSTRKRKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTITKRRKKRNRSSSVSSSAASSPERKKRILKPQLKSESSTSAFSTPTRSIPPRHNAAQINGKTESSSVVRTRSNRVVVDPVVTEQPSTSSAAKTFITKANASAIPGKTILENSVKHSKALNTLSSPGQSSFSHGTRNNSAKENMEKEKPVKRKMKSSVLPKASTLSKSSAVIEQGDCKNNALVPGTIQVNGHGGQPSKLVKRGPGRKPKVEVNTNSGEIIHKKRGRKPKKLQYAKPEDLEQNNVHPIRDEVLPSSTCNFLSETNNVKEDLLQKKNRGGRKPKRKMKTQKLDADLLVPASVKVLRRSNRKKIDDPIDEEEEFEELKGSEPHMRTRNQGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAKANLIGW", "length": 1821 }, "evidence": [ { "id": "HGNC:15673", "url": "https://alliancegenome.org/gene/HGNC:15673#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-261", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-261#orthology", "database": "AGR" }, { "id": "MGI:1932404", "url": "https://alliancegenome.org/gene/MGI:1932404#orthology", "database": "AGR" }, { "id": "RGD:1564964", "url": "https://alliancegenome.org/gene/RGD:1564964#orthology", "database": "AGR" }, { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q921C3-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "Brwd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEVPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGPPPSLVEIHRGRQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFDAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMSARISGDTSSEEERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENSADEHLVPQLGYVATSDGEVIEQIISLHTNDSGDASPESSVLDGMIRQLQQQQDQRLGVDQDGTANGLPSGEGTPRRGSFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQIATERDLQAWKRRVVVPEAPPGMFRRLEDIRIERGEEERNLYVIGRKKKTFQVPQKSNSMVLVSQSRQRTCRRKYANYSRRNADQCELSSGNESSGSVRHETSYDQSEGSCSSEDDEWRNDRRSGSDSDSSSDSSSQYSDWTADTGINLQPPLRMSCRRRVTRFCSTSEDEMSMENISPPKRRRKRRKESKPKRESLRRMTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPHKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTETEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQEGEWGQRSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALIWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQDCTNISELCNTSDNDEDDSADDLDDSDLPKTSSGRRKVHNWKRRSRASGCIESDWRRQCKALLILIFQCEDSEPFRQPVDLDEYPDYRDIIDTPMDFGTVRETLEAGNYDSPVEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISFDFKIGQKFKEKLRRSQRFKQRQNCNGAVPGDRRRRNVKQKQFKSQTKVIPQLMCPPSQSTSSKVPLSATRKTSAGVSSGFTSGDSSDSAGSLERVRRQRPEVLRSGSVLFGSEMEDFLATSSSSSASNSSEESKASPGARESSLRSGVLRGSNLGVTRTRAARRKAGSVSLENGCGRKATRKRVYLSDSDNNSVETDENLKNRKCGSSRKVLRKCAAVAASKIKLMSDAEDSSSESPCSGRKLPHRNASAVARKKLLHNSDDQSLKSETEELKDQNQSLLISGPHSVHNSISDSESDSDLRATRKTWNANGCTSHTAATCKTKSRPIESSEEDSRCHGSDHGPSSTGDPSTSGQKLRADSISEEADSEPESSVLCKNTHLCKKAKILSDSEDCEEKCGERRGPEVEGSPVSEALREAILAPQCLSHRGSETDVDSDGGAVREKSYSNENGSVSLENGQRRKVSRKSSSDKESNLQVTQKSPKDRSSPSRITQRASVATDKMKLTSDAEDLSLESVCTRSKRRRKKPARFACTPAKTALSSEEKHAHCEVPEAQPACRNKLPEPEHQDSAENPSQAASADLNSGGGSSFEQRKSIQSRQMGAVCVRPPPKTQSSSAGLSQENARSQTLDSETSLPSESVLTQKATVESNFEEELNYGLRRWNGRRLRTYGKAPLSRTAQVTPSLQASAEVGVKRRRMHPEVDGEDVPGQMGSSGCGPDTSPKASDLGSVTDSDVDCTDNTQTQRKKKRKGKARVLSKESVRKDREPHTKMRPCMLNEKDAVQMHSDTLKAKTVPEKVPRRCATVAANKIKMMCNLKEVVSGPENVGIRTISRKLPYRQASAAAKKKLLSVYKEDDAPIHSENEKELYLRRFRSRKEKAQPTPR", "length": 2304 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NSI6-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "BRWD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHETSCDQSEGSGSSEEDEWRSDRKSESYSESSSDSSSRYSDWTADAGINLQPPLRTSCRRRITRFCSSSEDEISTENLSPPKRRRKRKKENKPKKENLRRMTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQMGDEVIYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGIRYEVGPPTLCCLKLAFIDPATGKLMDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQSCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTTDELEKLLYKPQAGEWGQKSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKFNEKLRRSQRFKQRQNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTAYLGTHKTSAGISSGVTSGDSSDSAESSERRKRNRPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVTRTRAAQRKTGPVSLANGCGRKATRKRVYLSDSDNNSLETGEILKARAGNNRKVLRKCAAVAANKIKLMSDVEENSSSESVCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDENQLLPVSSSHTAQSNVDESENRDSESESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHACNRTAGPSTSVQKLKAESISEEADSEPGRSGGRKYNTFHKNASFFKKTKILSDSEDSESEEQDREDGKCHKMEMNPISGNLNCDPIAMSQCSSDHGCETDLDSDDDKIEKPNNFMKDSASQDNGLSRKISRKRVCSSDSDSSLQVVKKSSKARTGLLRITRRCAATAANKIKLMSDVEDVSLENVHTRSKNGRKKPLHLACTTAKKKLSDCEGSVHCEVPSEQYACEGKPPDPDSEGSTKVLSQALNGDSDSEDMLNSEHKHRHTNIHKIDAPSKRKSSSVTSSGEDSKSHIPGSETDRTFSSESTLAQKATAENNFEVELNYGLRRWNGRRLRTYGKAPFSKTKVIHDSQETAEKEVKRKRSHPELENVKISETTGNSKFRPDTSSKSSDLGSVTESDIDCTDNTKTKRRKTKGKAKVVRKEFVPRDREPNTKVRTCMHNQKDAVQMPSETLKAKMVPEKVPRRCATVAANKIKIMSNLKETISGPENVWIRKSSRKLPHRNASAAAKKKLLNVYKEDDTTINSESEKELEDINRKMLFLRGFRSWKENAQ", "length": 2320 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VC96-1", "protein_name": "BRWD3", "gene_name": "BRWD3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METRQPSSGDDLKPELYFLISKFLAAGPLEETAKVLIRELEEKKVLPRRLDWQGNEHEQTFEELERKYKHIGANHLLEICSRLGPLVDRELPPSVPGINSLLGTGRQNLLRTKETVYCHRSLRDYCTRLNGVSLPDSVLTKPTHNLDRVLTGREHGGEVRRKLLVPTDLYRRTKLLRRTVGHLSSVYCVLFDRTGRYIITGADDLLIKIWSAADGRLLATLRGASSEITDIAINLDNTMLAAGSLDHILRVWDMQTTSPIAVLSAHTGMITSVNFCPSPRSDLKYLVTTSTDGSIAFWQYSTPRGQKITFAPKPTQYHEKLRPGQAQMMCTTFSPGGIFLAAGSADHHVRVYMMGEDGPKRILETEAYTDAVDSVQWSHRGLRFISGSKDGTAHIWTFESQQWKSSKLCMTERLASCPEPEEGKRLKVTMVAWDASDRYVITAVNDFTIKIWDSKSAKLHRVLRGHKDELYVLESNPRDEHVLLSAGHDGQVFLWDIEQGVCVANFLNDIDGQGHGSVFDAKWSPDGTMIAATDSHGHILIFGLGVCIEKYKMLPTELFFHTDFRPLLRDAQHHVVDEQTQIMPHLMPPPFLVDADGNPHPSRFQRFVPGRESCSLDQLIPNLTVGVDGVVIDDGGAGGDAVVAAAPAEAPPAALPPAAAGGPQGANYSHIDRMIAALANRQSVNVNANDANPTNGNQSFERLTNRQMPDSNGRQSSRGNVLGSRLSTPRQGWGAAAAAPVEDQAGPSQPPAEPAAEPGQAQVQQALPLKFIRRTYVRPMKYPQLQNLKQTIYSAGQFEKQEYKREMRRRPIMINTASAASSQQPGSVGRPRNTRGNGGGARAGRRRGPQPAGGQPQPAYRTRAVRDQEPEHYDEVAPPPEEEEEDVSSNSSGDTSYSNVEENLEDSSDESETDSSDYSDWVADTPGPNLEPPKRSKRKPLSRRPRSSDDSSDDERAGRSRGGQVTARKVGRKTVLFPPTDANGEIPELYRPAEWLSEVIPRKAPYYPQMGDEVVYFRQGHAKYLDAVRLKKVYKLSHSSEPWNFHTLRDHELVRVIGIKYEIRPPRLCCLKLAIIDEEGNMTGTTFKIKYHDMPDVLDFLVLRQTFDLAVQRNWSIGDRFRCMIVDGWWMGQIESRHALSADFPDSSFMCFRVRWDNGEYEFMSPWDMEPIDQQRVPDEVGGAVPVLPEEIRATLYQPKSEEWHRGDRDGTCRRIINGLEQVMRLSIAEHFLAPVDLNIYPDYAYLIEYPIDLTTIKSRFENHFYRRITSAQFDVRYLATNAEQYNRRHAIIVKHSRIVTDLCLRIIREPDEIDVAAVYHQLADVYHSSESENEVDSDVVPSTSTGPTTSAAAAAARQRVSSARRSTRIHSEGDWRADCRQLLDLMWARTDSAPFREPVDTIDFPDYLEIIATPMDLRTVKEDLLGGNYDDPLDFAKDVRLIFQNSKNYNTNKRSRIYAMTLRLSALFESHIKTVVTSWKAALRRANKNKSGSSGGGRGGSSSSPNKRVKKERSTRRNQKPTAAARRLPVANSSEDEDEEDDDDDDDDDDEEEASTRGRSRRRNGVAVSASSSGSNRVTSSSAAQQRRGKSSSSEEEEEEETSAQATSDASSDEEERAQSNDSSPQQTRTRRARQRQRLSDDSNINDSEDSYNPNEGRGSRRRPGAARPSSNRQTNGHSSKRRRLNKSPANAAPGPSLPRRTRRIAGSSAEEAASHSQHDESTQDSQIGRRKGRSASSRSIGNGPSTSAAAAANSSLESPSRNTRANGTRTSSHLGAENDHSYHLPVRNGRIIESDTDSPVIRPTRQSAKRALMDWGRGSDIEEEEEEEEEDSEEAEEILPTPTKDDLPSTSRAALAQAAAGPSRQLRTNRNTVVRPAQSDDDDDDDSDNEPLANNQQKNYQSPAKSSSTATVAPHPLSLRRRLASPPERNTHMTRSHATSTTSSAAASRAEQQPAVSTHDHNYLGNVNSSRAPRRILSRHQRNADELDTSLDVLENSRLLSAIANHRRPTSTTNSNSASNVVTRRLRGRASQANSHDEDHEEEEAAASDEGTDGGSSSQSYEDEDEDSDSEDNQPLTSYVSPSNGRPRRKAKTSSSSATTQERPLRRTRRPPSNNSIANDNDDDDDYVVPRSRRANRGGNQRAGRNQKRPRYNEQSEEEEAAAGYSHRSKRIRNGDAHASSQERSQASTERDQEEEEDGTSVDSEEQQVNVSSRGRVRKPSAKARGIFKE", "length": 2232 }, "evidence": [ { "id": "HGNC:15673", "url": "https://alliancegenome.org/gene/HGNC:15673#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-261", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-261#orthology", "database": "AGR" }, { "id": "MGI:1932404", "url": "https://alliancegenome.org/gene/MGI:1932404#orthology", "database": "AGR" }, { "id": "RGD:1564964", "url": "https://alliancegenome.org/gene/RGD:1564964#orthology", "database": "AGR" }, { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE61", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of apoptotic process", "id": "GO:0043066", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043066", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE61", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE61", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE61", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1558, "end_pos": 1560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1658, "end_pos": 1660, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1683, "end_pos": 1685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 835, "end_pos": 837, "annotation": "n_glycosylation_sequon" }, { "start_pos": 871, "end_pos": 873, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PE61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE61" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 1162, "end_pos": 1232, "start_aa": "Cys", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 1558, "end_pos": 1560 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 1658, "end_pos": 1660 }, { "start_pos": 1683, "end_pos": 1685 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 835, "end_pos": 837 }, { "start_pos": 871, "end_pos": 873 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PEH4-1", "uniprot_ac": "A0A8M9PEH4", "uniprot_id": "A0A8M9PEH4_DANRE", "mass": { "chemical_mass": 37660.0, "monoisotopic_mass": 37660.0 }, "refseq": { "ac": "XP_021329552", "name": "rho GTPase-activating protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329552" }, "gene_names": [ { "name": "si:dkey-11e23.9", "type": "recommended", "evidence": [ { "id": "A0A8M9PEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4" } ] }, { "name": "si:dkey-11e23.9", "type": "synonym", "evidence": [ { "id": "XP_021329552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329552" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021329552", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329552" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021329552.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329552", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329552" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEH4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-11e23.9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4", "locus": {} } ], "crossref": [ { "id": "cd00159", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00159", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100006878", "url": "https://www.ncbi.nlm.nih.gov/gene/100006878", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100006878", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006878", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR45808", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45808", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45808:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45808:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021329552", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329552", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PEH4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PEH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TCN6", "url": "https://www.uniprot.org/uniprotkb/A0AB32TCN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TCN6-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TCN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYE7", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYE7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYF2", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYF2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYF8", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYF8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYG3", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYG3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTVSKEFNVCVWRNVIHFMFKGTLIVTYNSHLLDSCMSTHLLVFSFLTLFLVQEEAPSKVFGVPLSHLRKTGLMRQGLPLALTHLVGFLEKHGLSTCGLFRVGGTVLRQYELRKCFDRGGFPKMNVEDVHSSAYVLKHFLRTLPGGLIPEPFMIELLKVFKMFRLSKRHKAVKKILDTIPEENYNILCLLTFFLSRVAAASHANRMTTTNLSIEFGPIIFHVPQGPTKLEEEEMCISFTEYMLDNLRHLLPNIYPQASAINTAEGDAVSEAEEDFTPKKCVQQVLLAETSSKPAKIGRLGRLRRRFLHFWQKFGSRNGRCKVEPSGAGDVQ", "length": 332, "header": "tr|A0A8M9PEH4-1|A0A8M9PEH4_DANRE Isoform 1 of Rho GTPase-activating protein 1 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-11e23.9 PE=4 SV=2 CANONICAL=A0A8M9PEH4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PEH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4/entry#A0A8M9PEH4-1", "sequence": { "sequence": "MLTVSKEFNVCVWRNVIHFMFKGTLIVTYNSHLLDSCMSTHLLVFSFLTLFLVQEEAPSKVFGVPLSHLRKTGLMRQGLPLALTHLVGFLEKHGLSTCGLFRVGGTVLRQYELRKCFDRGGFPKMNVEDVHSSAYVLKHFLRTLPGGLIPEPFMIELLKVFKMFRLSKRHKAVKKILDTIPEENYNILCLLTFFLSRVAAASHANRMTTTNLSIEFGPIIFHVPQGPTKLEEEEMCISFTEYMLDNLRHLLPNIYPQASAINTAEGDAVSEAEEDFTPKKCVQQVLLAETSSKPAKIGRLGRLRRRFLHFWQKFGSRNGRCKVEPSGAGDVQ", "length": 332, "header": "tr|A0A8M9PEH4-1|A0A8M9PEH4_DANRE Isoform 1 of Rho GTPase-activating protein 1 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-11e23.9 PE=4 SV=2 CANONICAL=A0A8M9PEH4-1" }, "locus": {} }, { "isoform_ac": "A0AB32TCN6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4/entry#A0AB32TCN6-1", "sequence": { "sequence": "MGVLSVCEEAPSKVFGVPLSHLRKTGLMRQGLPLALTHLVGFLEKHGLSTCGLFRVGGTVLRQYELRKCFDRGGFPKMNVEDVHSSAYVLKHFLRTLPGGLIPEPFMIELLKVFKMFRLSKRHKAVKKILDTIPEENYNILCLLTFFLSRVAAASHANRMTTTNLSIEFGPIIFHVPQGPTKLEEEEMCISFTEYMLDNLRHLLPNIYPQASAINTAEGDAVSEAEEDFTPKKCVQQVLLAETSSKPAKIGRLGRLRRRFLHFWQKFGSRNGRCKVEPSGAGDVQ", "length": 285, "header": "tr|A0AB32TCN6-1|A0A8M9PEH4_DANRE Computationally mapped isoform of Rho GTPase-activating protein 1 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-11e23.9 PE=4 SV=1 CANONICAL=A0A8M9PEH4-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4/entry#A0AC58IYE7-1", "sequence": { "sequence": "MRQGLPLALTHLVGFLEKHGLSTCGLFRVGGTVLRQYELRKCFDRGGFPKMNVEDVHSSAYVLKHFLRTLPGGLIPEPFMIELLKVFKMFRLSKRHKAVKKILDTIPEENYNILCLLTFFLSRVAAASHANRMTTTNLSIEFGPIIFHVPQGPTKLEEEEMCISFTEYMLDNLRHLLPNIYPQASAINTAEGDAVSEAEEDFTPKKCVQQVLLAETSSKPAKIGRLGRLRRRFLHFWQKFGSRNGRCKVEPSGAGDVQ", "length": 258, "header": "tr|A0AC58IYE7-1|A0AC58IYE7_DANRE Computationally mapped isoform of Rho GTPase-activating protein 1 isoform X5 OS=Danio rerio OX=7955 GN=si:dkey-11e23.9 PE=4 SV=1 CANONICAL=A0A8M9PEH4-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4/entry#A0AC58IYF2-1", "sequence": { "sequence": "MGVLSVCEEAPSKVFGVPLSHLRKTGLMRQGLPLALTHLVGFLEKHGLSTCGLFRVGGTVLRQYELRKCFDRGGFPKMNVEDVHSSAYVLKHFLRTLPGGLIPEPFMIELLKVFKMFRLSKRHKAVKKILDTIPEENYNILCLLTFFLSRVAAASHANRMTTTNLSIEFGPIIFHVPQGPTKLEEEEMCISFTEYMLDNLRHLLPNIYPQASAINTAGDAVSEAEEDFTPKKCVQQVLLAETSSKPAKIGRLGRLRRRFLHFWQKFGSRNGRCKVEPSGAGDVQ", "length": 284, "header": "tr|A0AC58IYF2-1|A0AC58IYF2_DANRE Computationally mapped isoform of Rho GTPase-activating protein 1 isoform X4 OS=Danio rerio OX=7955 GN=si:dkey-11e23.9 PE=4 SV=1 CANONICAL=A0A8M9PEH4-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4/entry#A0AC58IYF8-1", "sequence": { "sequence": "MLTVSKEFNVCVWRNVIHFMFKGTLIVTYNSHLLDSCMSTHLLVFSFLTLFLVQEEAPSKVFGVPLSHLRKTGLMRQGLPLALTHLVGFLEKHGLSTCGLFRVGGTVLRQYELRKCFDRGGFPKMNVEDVHSSAYVLKHFLRTLPGGLIPEPFMIELLKVFKMFRLSKRHKAVKKILDTIPEENYNILCLLTFFLSRVAAASHANRMTTTNLSIEFGPIIFHVPQGPTKLEEEEMCISFTEYMLDNLRHLLPNIYPQASAINTAGDAVSEAEEDFTPKKCVQQVLLAETSSKPAKIGRLGRLRRRFLHFWQKFGSRNGRCKVEPSGAGDVQ", "length": 331, "header": "tr|A0AC58IYF8-1|A0AC58IYF8_DANRE Computationally mapped isoform of Rho GTPase-activating protein 1 isoform X2 OS=Danio rerio OX=7955 GN=si:dkey-11e23.9 PE=4 SV=1 CANONICAL=A0A8M9PEH4-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4/entry#A0AC58IYG3-1", "sequence": { "sequence": "MRQGLPLALTHLVGFLEKHGLSTCGLFRVGGTVLRQYELRKCFDRGGFPKMNVEDVHSSAYVLKHFLRTLPGGLIPEPFMIELLKVFKMFRLSKRHKAVKKILDTIPEENYNILCLLTFFLSRVAAASHANRMTTTNLSIEFGPIIFHVPQGPTKLEEEEMCISFTEYMLDNLRHLLPNIYPQASAINTAGDAVSEAEEDFTPKKCVQQVLLAETSSKPAKIGRLGRLRRRFLHFWQKFGSRNGRCKVEPSGAGDVQ", "length": 257, "header": "tr|A0AC58IYG3-1|A0AC58IYG3_DANRE Computationally mapped isoform of Rho GTPase-activating protein 1 isoform X6 OS=Danio rerio OX=7955 GN=si:dkey-11e23.9 PE=4 SV=1 CANONICAL=A0A8M9PEH4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100006878", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006878", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEH4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PEH4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH4" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 251, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P6K6-1", "uniprot_ac": "A0A8M9P6K6", "uniprot_id": "A0A8M9P6K6_DANRE", "mass": { "chemical_mass": 188810.0, "monoisotopic_mass": 188810.0 }, "refseq": { "ac": "XP_021326252", "name": "protein MON2 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326252" }, "gene_names": [ { "name": "mon2", "type": "recommended", "evidence": [ { "id": "A0A8M9P6K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6" } ] }, { "name": "mon2", "type": "synonym", "evidence": [ { "id": "XP_021326252", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326252" } ] } ], "protein_names": [ { "name": "Protein MON2 homolog", "type": "recommended", "evidence": [ { "id": "A0A8M9P6K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6/entry#names_and_taxonomy" } ] }, { "name": "protein MON2 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021326252", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326252" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326252", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326252" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6K6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mon2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-2712", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2712", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P6K6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P6K6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100334806", "url": "https://www.ncbi.nlm.nih.gov/gene/100334806", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015403", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015403", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032629", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032629", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100334806", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100334806", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR10663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10663:SF333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10663:SF333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34199", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34199", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34199:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34199:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09324", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09324", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12783", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12783", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16206", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16206", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16213", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16213", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021326252", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326252", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P6K6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P6K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PYL9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PYL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PYL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PYL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IWI8", "url": "https://www.uniprot.org/uniprotkb/A0AC58IWI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IWI8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IWI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-2712", "url": "https://zfin.org/ZDB-GENE-030131-2712", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSLKMSTSSPEAVKKLLENMQADLRSLSMECKKKFPPVKEAAESGIVKIKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENGLEELKLLQTVLVLLTTNTIVHDEVLSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERMVAEDERFKGLNEEPPAVQGNCNRRSVSTLRPSAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSSSSASPAPVEKPYFPICMRLLRVVSVLIKHFYSLLVTECEIFLSLLVKFLDGEKPQWLRAVAVESVHRLCVQPHLLRSFCQSYDMKPHSTKVFRDIVNALGSFIQSLFILPSAGNTSSTSTPAGGSVSSSQASGPGGPGLTGAGGALTTQAAFEYRGTWIPLMNVSVQGSAKATYLEMLDKVEPPSIPEGYAMSVAFSALLDLVRGITNMIDRELLRQEQQEAMREEEEPVSPPAQEPLAAEVWQEMVNACWCGLLAALSLLLDASTDETATENILKAELSMASLCGRLGLVTPRDAFITAVCKASLPPHYALTILSSSASSLTNKVYSIQGQSVQMVSPSSESHQQVVAVGQPLSAQPQGTVVLTAKNIQCMRTLLNLAHCHGAHLGTSWQLVLATLQHLVWILGLKPAPGGVLKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSMEAMEMAYGTNKEPSLFAVAKLLETGLVNMDRIEILWRPLTAHLLEVCQHPNARMREWGAEAITSLIKAGLSYKHDPPLSQNQRLQLLLLNPLKELSNVLHADIRQKQLECVLQILQNQGDSLGPGWPLVLGVIGAIRNDQGESLIRTAFQCLQLVVTDFLPTMPCMCLQIVVDVAGSFGLQNQELNISLTSIGLLWNISDYFFQRGEAITEELDKEEAVLLKQAQDKGEPLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTMFSTIAAHGTLLQPPTWNIVVWKVLFHLLDCVRKSSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQQLGDFFKAWEVLLDHIQSAALSKNNEVSLAALKSFQEILQLVTPIKDTDKPDALSAIDVPSVLMESLQGSGPGRPLVRSDSLAERLAQRYAAQPSLPPPGEELDDSALWWSAWNTWYRVGTECTRPPSGGTDKLVFVPSQPFLTALIQIFPALYQHIAGGFSMEDLKKLGVILHGAVSVPISSDSSPFILPSYTEAVLTSLQEAVLTALDVLQKAICVSSENLQVMYPAIFEQLLLFVEFSCKPPQYGKMETKHVANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYHKTACHKAVINEKVLQNIIKTVRIPLGLKYACPAESTWKLAVSSLLKVLSIGLPVARQQASSGKFDTMWPELANAFEDFLFTKSTPPDNLSIQEFQRNEAVDVEVVQLISSEILPFANFIPKEFVGRIMSMLNKGSIHSQSSSFTEAEMDMRMREDFSKVCFETLLQFSFSNKVSTPQEGFISRMALSVLLQRAQDVLRRYVEDERLSGRCPLPRQQVTEIIFVLKAISTLMDSLKKTQPENVDGNVWAQVIALYPTLVECITCTSPEVSSALKDALGPFKDFMQPPVSKVQNGES", "length": 1711, "header": "tr|A0A8M9P6K6-1|A0A8M9P6K6_DANRE Isoform 1 of Protein MON2 homolog OS=Danio rerio OX=7955 GN=mon2 PE=1 SV=1 CANONICAL=A0A8M9P6K6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P6K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6/entry#A0A8M9P6K6-1", "sequence": { "sequence": "MSLKMSTSSPEAVKKLLENMQADLRSLSMECKKKFPPVKEAAESGIVKIKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENGLEELKLLQTVLVLLTTNTIVHDEVLSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERMVAEDERFKGLNEEPPAVQGNCNRRSVSTLRPSAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSSSSASPAPVEKPYFPICMRLLRVVSVLIKHFYSLLVTECEIFLSLLVKFLDGEKPQWLRAVAVESVHRLCVQPHLLRSFCQSYDMKPHSTKVFRDIVNALGSFIQSLFILPSAGNTSSTSTPAGGSVSSSQASGPGGPGLTGAGGALTTQAAFEYRGTWIPLMNVSVQGSAKATYLEMLDKVEPPSIPEGYAMSVAFSALLDLVRGITNMIDRELLRQEQQEAMREEEEPVSPPAQEPLAAEVWQEMVNACWCGLLAALSLLLDASTDETATENILKAELSMASLCGRLGLVTPRDAFITAVCKASLPPHYALTILSSSASSLTNKVYSIQGQSVQMVSPSSESHQQVVAVGQPLSAQPQGTVVLTAKNIQCMRTLLNLAHCHGAHLGTSWQLVLATLQHLVWILGLKPAPGGVLKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSMEAMEMAYGTNKEPSLFAVAKLLETGLVNMDRIEILWRPLTAHLLEVCQHPNARMREWGAEAITSLIKAGLSYKHDPPLSQNQRLQLLLLNPLKELSNVLHADIRQKQLECVLQILQNQGDSLGPGWPLVLGVIGAIRNDQGESLIRTAFQCLQLVVTDFLPTMPCMCLQIVVDVAGSFGLQNQELNISLTSIGLLWNISDYFFQRGEAITEELDKEEAVLLKQAQDKGEPLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTMFSTIAAHGTLLQPPTWNIVVWKVLFHLLDCVRKSSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQQLGDFFKAWEVLLDHIQSAALSKNNEVSLAALKSFQEILQLVTPIKDTDKPDALSAIDVPSVLMESLQGSGPGRPLVRSDSLAERLAQRYAAQPSLPPPGEELDDSALWWSAWNTWYRVGTECTRPPSGGTDKLVFVPSQPFLTALIQIFPALYQHIAGGFSMEDLKKLGVILHGAVSVPISSDSSPFILPSYTEAVLTSLQEAVLTALDVLQKAICVSSENLQVMYPAIFEQLLLFVEFSCKPPQYGKMETKHVANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYHKTACHKAVINEKVLQNIIKTVRIPLGLKYACPAESTWKLAVSSLLKVLSIGLPVARQQASSGKFDTMWPELANAFEDFLFTKSTPPDNLSIQEFQRNEAVDVEVVQLISSEILPFANFIPKEFVGRIMSMLNKGSIHSQSSSFTEAEMDMRMREDFSKVCFETLLQFSFSNKVSTPQEGFISRMALSVLLQRAQDVLRRYVEDERLSGRCPLPRQQVTEIIFVLKAISTLMDSLKKTQPENVDGNVWAQVIALYPTLVECITCTSPEVSSALKDALGPFKDFMQPPVSKVQNGES", "length": 1711, "header": "tr|A0A8M9P6K6-1|A0A8M9P6K6_DANRE Isoform 1 of Protein MON2 homolog OS=Danio rerio OX=7955 GN=mon2 PE=1 SV=1 CANONICAL=A0A8M9P6K6-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PYL9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6/entry#A0A8M9PYL9-1", "sequence": { "sequence": "MSLKMSTSSPEAVKKLLENMQADLRSLSMECKKKFPPVKEAAESGIVKIKTIAARNTDILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENGLEELKLLQTVLVLLTTNTIVHDEVLSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERMVAEDERFKGLNEEPPAVQGNCNRRSVSTLRPSAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSSSSASPAPVEKPYFPICMRLLRVVSVLIKHFYSLLVTECEIFLSLLVKFLDGEKPQWLRAVAVESVHRLCVQPHLLRSFCQSYDMKPHSTKVFRDIVNALGSFIQSLFILPSAGNTSSTSTPAGGSVSSSQASGPGGPGLTGAGGALTTQAAFEYRGTWIPLMNVSVQGSAKATYLEMLDKVEPPSIPEGYAMSVAFSALLDLVRGITNMIDRELLRQEQQEAMREEEEPVSPPAQEPLAAEVWQEMVNACWCGLLAALSLLLDASTDETATENILKAELSMASLCGRLGLVTPRDAFITAVCKASLPPHYALTILSSSASSLTNKVYSIQGQSVQMVSPSSESHQQVVAVGQPLSAQPQGTVVLTAKNIQCMRTLLNLAHCHGAHLGTSWQLVLATLQHLVWILGLKPAPGGVLKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSMEAMEMAYGTNKEPSLFAVAKLLETGLVNMDRIEILWRPLTAHLLEVCQHPNARMREWGAEAITSLIKAGLSYKHDPPLSQNQRLQLLLLNPLKELSNVLHADIRQKQLECVLQILQNQGDSLGPGWPLVLGVIGAIRNDQGESLIRTAFQCLQLVVTDFLPTMPCMCLQIVVDVAGSFGLQNQELNISLTSIGLLWNISDYFFQRGEAITEELDKEEAVLLKQAQDKGEPLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTMFSTIAAHGTLLQPPTWNIVVWKVLFHLLDCVRKSSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQQLGDFFKAWEVLLDHIQSAALSKNNEVSLAALKSFQEILQLVTPIKDTDKPDALSAIDVPSVLMESLQGSGPGRPLVRSDSLAERLAQRYAAQPSLPPPGEELDDSALWWSAWNTWYRVGTECTRPPSGGTDKLVFVPSQPFLTALIQIFPALYQHIAGGFSMEDLKKLGVILHGAVSVPISSDSSPFILPSYTEAVLTSLQEAVLTALDVLQKAICVSSENLQVMYPAIFEQLLLFVEFSCKPPQYGKMETKHVANAKYNQAEWVALNYVPFAERSLEVVVDLYHKTACHKAVINEKVLQNIIKTVRIPLGLKYACPAESTWKLAVSSLLKVLSIGLPVARQQASSGKFDTMWPELANAFEDFLFTKSTPPDNLSIQEFQRNEAVDVEVVQLISSEILPFANFIPKEFVGRIMSMLNKGSIHSQSSSFTEAEMDMRMREDFSKVCFETLLQFSFSNKVSTPQEGFISRMALSVLLQRAQDVLRRYVEDERLSGRCPLPRQQVTEIIFVLKAISTLMDSLKKTQPENVDGNVWAQVIALYPTLVECITCTSPEVSSALKDALGPFKDFMQPPVSKVQNGES", "length": 1705, "header": "tr|A0A8M9PYL9-1|A0A8M9P6K6_DANRE Computationally mapped isoform of Protein MON2 homolog OS=Danio rerio OX=7955 GN=mon2 PE=1 SV=1 CANONICAL=A0A8M9P6K6-1" }, "locus": {} }, { "isoform_ac": "A0AC58IWI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6/entry#A0AC58IWI8-1", "sequence": { "sequence": "MKPTFLLFCQVCQHPNARMREWGAEAITSLIKAGLSYKHDPPLSQNQRLQLLLLNPLKELSNVLHADIRQKQLECVLQILQNQGDSLGPGWPLVLGVIGAIRNDQGESLIRTAFQCLQLVVTDFLPTMPCMCLQIVVDVAGSFGLQNQELNISLTSIGLLWNISDYFFQRGEAITEELDKEEAVLLKQAQDKGEPLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTMFSTIAAHGTLLQPPTWNIVVWKVLFHLLDCVRKSSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQQLGDFFKAWEVLLDHIQSAALSKNNEVSLAALKSFQEILQLVTPIKDTDKPDALSAIDVPSVLMESLQGSGPGRPLVRSDSLAERLAQRYAAQPSLPPPGEELDDSALWWSAWNTWYRVGTECTRPPSGGTDKLVFVPSQPFLTALIQIFPALYQHIAGGFSMEDLKKLGVILHGAVSVPISSDSSPFILPSYTEAVLTSLQEAVLTALDVLQKAICVSSENLQVMYPAIFEQLLLFVEFSCKPPQYGKMETKHVANAKYNQAEWVALNYVPFAERSLEVVVDLYHKTACHKAVINEKVLQNIIKTVRIPLGLKYACPAESTWKLAVSSLLKVLSIGLPVARQQASSGKFDTMWPELANAFEDFLFTKSTPPDNLSIQEFQRNEAVDVEVVQLISSEILPFANFIPKEFVGRIMSMLNKGSIHSQSSSFTEAEMDMRMREDFSKVCFETLLQFSFSNKVSTPQEGFISRMALSVLLQRAQDVLRRYVEDERLSGRCPLPRQQVTEIIFVLKAISTLMDSLKKTQPENVDGNVWAQVIALYPTLVECITCTSPEVSSALKDALGPFKDFMQPPVSKVQNGES", "length": 903, "header": "tr|A0AC58IWI8-1|A0AC58IWI8_DANRE Computationally mapped isoform of Protein MON2 homolog isoform X3 OS=Danio rerio OX=7955 GN=mon2 PE=1 SV=1 CANONICAL=A0A8M9P6K6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 418, "start_aa": "Thr", "end_pos": 418, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr418", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100334806", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100334806", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZCG3-1", "protein_name": "Protein MON2 homolog", "gene_name": "Mon2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSCTNSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKVTQLCLAAIQRLMSHEVVSEAAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERMVAEDDRHRDIDPPVLIQGNSNRRSVSTLRPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSGTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRLCVQPRLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPAAANQAGNNNAGGPASAPANSGVVGIGAGVTLLPAFEYRGAWIPILTITVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEVETECPTVTEGASSQSSERRDEQSESDHMDQETVSRAVWEEMVSACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNATTAATLSNKSYSIQGQSVMMISPSSESHQQVVAVGQPLAVQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPSSGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEKVCQHPNSRMREWGAEALTSLIKAGLTFNHEPPLSQNQRLQLLLLNPLKEMSNINHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRNDQGESLIRTAFQCLQLVVTDFLPTMPCSCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVSLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHATWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPARDSEKPETPVGTVPVPVLIGNISGQGLSRPFVRTDSIGEKLGRCSSEPPVVTDEAEDLKLWWAAWNTWHRTGSESTEPPSTFDELTFIPSQPFLTALIQIFPALYQHIKAGFSMADLQKLGVILHSAVSVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFEQLLAFVEFSCKPPQYGQLETKHIANAKHNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQSIIKTLRVPLSLKYSCPSESTWKLAVASLLKVLSIGLPVARQHASSGKFDSMWPELASTLEDFLFTKSIPPDNLSIQEFQRNESIDVEVVQLISAEILPYANLIPKAFVAQMMTMLNRGSIHSQPSSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWAQVIALYPTLVECITCSSSDVCSALKEALVPFKDFMQPPASKVQNGES", "length": 1715 }, "evidence": [ { "id": "MGI:1914324", "url": "https://alliancegenome.org/gene/MGI:1914324#orthology", "database": "AGR" }, { "id": "HGNC:29177", "url": "https://alliancegenome.org/gene/HGNC:29177#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2712", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2712#orthology", "database": "AGR" }, { "id": "FB:FBgn0031985", "url": "https://alliancegenome.org/gene/FB:FBgn0031985#orthology", "database": "AGR" }, { "id": "RGD:1308808", "url": "https://alliancegenome.org/gene/RGD:1308808#orthology", "database": "AGR" }, { "id": "SGD:S000005241", "url": "https://alliancegenome.org/gene/SGD:S000005241#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P48563-1", "protein_name": "Protein MON2", "gene_name": "MON2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAMNTGGFDSMQRQLEAELRSLSSESKRRNSTIRHASDKSIEILKRVHSFEELERHPDFALPFVLACQSRNAKMTTLAMQCLQGLSTVPSIPRSRLSEILDAFIEATHLAMEIQLKVLQVVPIFFKTYGKFIYGPLCKKLLLCCSNLLHVPNKAPVVVGTASATLQQLIDEIFDRLSIESVVDDKQYEVLISNSESIKVNVYRYDANKLFDNICSLNEISSNGAVSDEEMLLDIGDIPIDYGLEILESILKNSQKNLLECQDLQYLLRVKAIPLLLRCISSSRHFSTAVRSCRCLKLLIRKEYLSILELELEVILSLLIHGISVESNLSGWQRVLSLELFKDLSQDPEIVNTLYMDYDNYPDKKHVFKYLLKECIVLLNSPEYITFLAPSKVVEKMDSPLITTENSTVKTKFMHLLDKSNAPSINITYIISLILTICNHLCEGLNKSALESSPLEKKIEDKEREEGTGNDSTVVKVYSGLFSGLFELNKLFLYSTSLETSIFHLVVRAFQKLAHSAGVLSLKDKLRACMKLFSILITNNVTSSNQYSFNDTSKSAKNQHTRNISTSSVTTSPVESTKNPSRSIADSAQNKEMKRRLHPRNISSRQVSLLRALISLSISLGPIFDSESWRYTFLTWQWITYYIYGPSADFKESFYSEDIPPPPILTKSDVTSIESSLTKFFESTSSYSCSTFHLVLTRLILDSKNTLTLEQTNLNLNNDIGYHPLDAKDEIIPCIYNKAFFVNKIGELATYNCKKFLFGKNGKELWSLISTYMIKLISNREMDNDSLRLYTVRVFTDIIKKATNEVGNSDEQDNKVKQFGTLENLVIDSLMATINSIKQLDIGKQEIYNGTINVESDILFQLLLTLKEILNEFGELLMNSWTNIFNIINSPFEWTVEDTDFSVNEDIDDSSLFEGIVQKHKNMIQVSYDVFKLISDDFLQSLPMSVIKFVIDTLVNFVSQKRNLNISFSSISQFWLVGDYLRVRFNPETLNLSDEKRRSLSEKINNQKLIEIITSSSSHDWELYNGLWIYLLKNLINCTNDDRVEVKNGAVQTFFRIIDSHSVCFPPWDLIFLEVIEPLLTKEWSTEELENETDFINVTLQGLIKLYPEHFKDFKNNTTCAKEWSMLLDFLKRLLSSTSNNTKNAVILNYQTLLKEIITIEDVPSDILKKCCEIFTDYNITYSDLSTNASSKTEYDCIYELITGFPPLYQLISKYDAMTDEFVEKVLLLFNSAIKYPLLPEFVQDKTKPSSMQKAILSGLDIFMTNDSKDTEILILLQLSTISILAFDTREKITKKLGPKLPKASLNRLPTFEAISYMSCSNLRNRIAKIDQFGISTLKAKHILRILKNLAEIIKRKSLITGSESDEIPIWVLASNCFCDLSNKIFKSLQEDAENPLKDNFCDLFINVIVVTLQRINPELDNLTEIDDLNEYSKYREILLENRIIDLFNERQLDTFIYAVWDCSFLYEFDELENALMQDCGTFSELSQKLSSFDFSCIFGSTTNPRFQTKYKCSLECLQDLVNFMLNTNEKLRKLTAPYLSARIALALRRYISDEYLIGRAPIPKLRKTELATLLNGLCVILRGVLDQNSTLGNKQIGVENLQTLSPLILRTIPVSHKMDGLQDKVLELSLGFTKLD", "length": 1636 }, "evidence": [ { "id": "MGI:1914324", "url": "https://alliancegenome.org/gene/MGI:1914324#orthology", "database": "AGR" }, { "id": "HGNC:29177", "url": "https://alliancegenome.org/gene/HGNC:29177#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2712", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2712#orthology", "database": "AGR" }, { "id": "FB:FBgn0031985", "url": "https://alliancegenome.org/gene/FB:FBgn0031985#orthology", "database": "AGR" }, { "id": "RGD:1308808", "url": "https://alliancegenome.org/gene/RGD:1308808#orthology", "database": "AGR" }, { "id": "SGD:S000005241", "url": "https://alliancegenome.org/gene/SGD:S000005241#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7Z3U7-1", "protein_name": "Protein MON2 homolog", "gene_name": "MON2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGTSSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERMVAEDERHRDIIEQPVLVQGNSNRRSVSTLKPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDADKPQWLRAVAVESIHRFCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPATSNQAGNNNLGGSVSAPANSGMVGIGGGVTLLPAFEYRGTWIPILTITVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITSMIEGELGELETECQTTTEEGSSPTQSTEQQDLQSTSDQMDKEIVSRAVWEEMVNACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNTTTAATLSNKSYSVQGQSVMMISPSSESHQQVVAVGQPLAVQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPSSGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEVCQHPNSRMREWGAEALTSLIKAGLTFNHDPPLSQNQRLQLLLLNPLKEMSNINHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRNDQGESLIRTAFQCLQLVVTDFLPTMPCTCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVVLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSDKPETPPVVNVPVPVLIGPISGMSRPFVRTDSIGEKLGRYSSSEPPIVTDELEDLNLWWAAWNTWYRIGSESTKPPITFDKLTFIPSQPFLTALIQIFPALYQHIKTGFNMDDLQKLGVILHSAISVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRVPLSLKYSCPSESTWKLAVSSLLRVLSIGLPVARQHASSGKFDSMWPELANTFEDFLFTKSIPPDNLSIQEFQRNENIDVEVVQLISNEILPYANFIPKEFVGQIMTMLNKGSIHSQSSSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWAQVIALYPTLVECITCSSSEVCSALKEALVPFKDFMQPPASRVQNGES", "length": 1717 }, "evidence": [ { "id": "MGI:1914324", "url": "https://alliancegenome.org/gene/MGI:1914324#orthology", "database": "AGR" }, { "id": "HGNC:29177", "url": "https://alliancegenome.org/gene/HGNC:29177#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2712", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2712#orthology", "database": "AGR" }, { "id": "FB:FBgn0031985", "url": "https://alliancegenome.org/gene/FB:FBgn0031985#orthology", "database": "AGR" }, { "id": "RGD:1308808", "url": "https://alliancegenome.org/gene/RGD:1308808#orthology", "database": "AGR" }, { "id": "SGD:S000005241", "url": "https://alliancegenome.org/gene/SGD:S000005241#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80TL7-1", "protein_name": "Protein MON2 homolog", "gene_name": "Mon2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCTNSPEAVKKLLENMQSDLRALSLECKKKFPPVKEAAESGIIKVKTIAARNTEILAALKENSSEVVQPFLMGCGTKEPKITQLCLAAIQRLMSHEVVSETAAGNIINMLWQLMENSLEELKLLQTVLVLLTTNTVVHDEALSKAIVLCFRLHFTKDNITNNTAAATVRQVVTVVFERMVAEDDRHRDIEPPVPIQGNSNRRSVSTLRPCAKDAYMLFQDLCQLVNADAPYWLVGMTEMTRTFGLELLESVLNDFPQVFLQHQEFSFLLKERVCPLVIKLFSPNIKFRQGSSTSSSPAPVEKPYFPICMRLLRVVSVLIKQFYSLLVTECEIFLSLLVKFLDSDKPQWLRAVAVESIHRLCVQPQLLRSFCQSYDMKQHSTKVFRDIVNALGSFIQSLFLVPPTGNPATANQAGNNNAGGPASAPANSGVVGVGGGVTLLPAFEYRGAWIPILTVTVQGSAKATYLEMLDKVEPPTIPEGYAMSVAFHCLLDLVRGITTMIEGELGEVEAEGPSVTEGASSQSSERRDEQAASDPMDQETVSRAVWEEMVSACWCGLLAALSLLLDASTDEAATENILKAELTMAALCGRLGLVTSRDAFITAICKGSLPPHYALTVLNATTAATLSNKSYSIQGQSVMMISPSSESHQQVVAVGQPLAVQPQGTVMLTSKNIQCMRTLLNLAHCHGAVLGTSWQLVLATLQHLVWILGLKPSSGGALKPGRAVEGPSTVLTTAVMTDLPVISNILSRLFESSQYLDDVSLHHLINALCSLSLEAMDMAYGNNKEPSLFAVAKLLETGLVNMHRIEILWRPLTGHLLEKVCQHPNSRMREWGAEALTSLIRAGLTFSHEPPLPQNQRLQLLLLNPLKEMSNINHPDIRLKQLECVLQILQSQGDSLGPGWPLVLGVMGAIRNDQGESLIRTAFQCLQLVVTDFLPTMPCSCLQIVVDVAGSFGLHNQELNISLTSIGLLWNISDYFFQRGETIEKELNKEEAAQQKQAEEKGVSLNRPFHPAPPFDCLWLCLYAKLGELCVDPRPAVRKSAGQTLFSTIGAHGTLLQHSTWHTVIWKVLFHLLDRVRESSTTADKEKIESGGGNILIHHSRDTAEKQWAETWVLTLAGVARIFNTRRYLLQPLGDFSRAWDVLLDHIQSAALSKNNEVSLAALKSFQEILQIVSPVRDSEKPEPPAVSVPVPVLLGNLSGPGLSRPFVRTDSIGEKLGRCGSETPVVTDELEDLKLWWAAWNTWHRTGSESTEPPSSVDELTFIPSQPFLTALVQIFPALYQHIKAGFSMADLQKLGVILHSAVSVPISSDASPFILPSYTEAVLTSLQEAVLTALDVLQKAICVGPENMQIMYPAIFDQLLAFVEFSCKPPQYGQLETKHIANAKYNQIQLFAPAEWVALNYVPFAERSLEVVVDLYQKTACHKAVVNEKVLQNIIKTLRVPLSLKYSCPSESTWKLAVASLLKVLSIGLPVARQHASSGKFDSMWPELASTLEDFLFTKSIPPDNLSIQEFQRNESIDVEVVQLISAEILPYANLIPKAFVGQMMTMLNKGSIHSQPCSFTEAEIDIRLREEFSKMCFETLLQFSFSNKVTTPQEGYISRMALSVLLKRSQDVLHRYIEDERLSGKCPLPRQQVTEIIFVLKAVSTLIDSLKKTQPENVDGNTWSQVIALYPTLVECITCSSSDVGSALKEALAPFKDFMQPPASRVQNGES", "length": 1715 }, "evidence": [ { "id": "MGI:1914324", "url": "https://alliancegenome.org/gene/MGI:1914324#orthology", "database": "AGR" }, { "id": "HGNC:29177", "url": "https://alliancegenome.org/gene/HGNC:29177#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2712", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2712#orthology", "database": "AGR" }, { "id": "FB:FBgn0031985", "url": "https://alliancegenome.org/gene/FB:FBgn0031985#orthology", "database": "AGR" }, { "id": "RGD:1308808", "url": "https://alliancegenome.org/gene/RGD:1308808#orthology", "database": "AGR" }, { "id": "SGD:S000005241", "url": "https://alliancegenome.org/gene/SGD:S000005241#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VLT1-1", "protein_name": "Protein MON2 homolog", "gene_name": "mon2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSFVGGGGCGGQDVHKFVEALQADFKTLSLETKKKYPQIKEACEEAISKLCTAGSSQQNSVYYTVNQILYPLVQGCETKDLKIIKFCLGMMQRLITQQVVDQKGALYITNALWTLMENNIEEVKVLQTVTLLLTTNTVVHGDTLAKALVLCFRLHYAKNPTIVNTAGATIRQLVSLVFERVYLEKDSVSSLQQQQSSGSPAEGEGGNQDVQTFASDAFLLFQDLVQLVNADQPYWLLGMTEMTRTFGLELLEAVLTNFSAVFHESNDFRLLLKERVCALVIKLFSPNVKHRQLPAPSNGNAPVPAEKPYFPISMRLLRLVAILIQKYHTILVTECEIFLSLIIKFLDPDKPAWQRALALEVIHKLVTRSSLIAFFCKSYDLKNHATNIVHDMIAAMGSYIRYSLINASAMLNGQQNGVANSLTAMSGSNQCGFMFRGAYLPLVATYAPGVSKAVYLEMLDKIDASNIPDSYGISVGHAILLDMTRSIGGVIQRTPELHPSHNTAVITEEEHKPLCLQLVNSSWSALLSAFIPLVETSIDEATTENILKAMQNYAALCGMLEQLQPRDAFIMAMCRASFPPHYAMSIFANTTQSDGDLRCHTRSGSQDLSSQFINSCSGDAGDFRPQIVAVGTPLPSASLPHSVMQAPVMLTNKNLQCMRAILFLAHNNGGILGTSWHIVLQTLQHLVWILGLKPSTGGSLQAMPKPAVEANVGIQTAVMADLPVLSQMLSQLFESSQYLDDVALHHLIDALCKLSHEAMELAYANREPSLFAVAKLLETGLVNMPRIKVLWRPLTNHLLEVCQHRHIRMREWGVEAITYLVKSALQFKHKTPLKENMELQTMLLSPLSELSTVLHADVRQRQLDCVLQILNTAGEILSFGWPAIIEIIGAVNEHHGEPLIRTAFQCLQLVITDFLTVMPWRCLPLCISTAAKFGSQTQELNISLTAIGLMWNISDFFNQNQDKLMSTQLQDVSILPDFPGTVKMPQFDKLWMCLYAKLGELCVDLRPAVRKSAGQTLFSTISAHGSLLNPPTWQALVWQVLFPLLDNVRALSSSASNEKVDASGNILIHHSRNTAQKQWAETQVLTLSGVCRVFNTKRELLQMLGDFERAWSLILEFIQNAALSKNGEVSLAALKSLQEIMYHNTAERTERALKDPQTAQEQDEEIWTIAWNIWLSIGMESTKMSTSTSAKLQQQNSNGAETQEDFYIPSQAFLTALIQIFPAIFQHIQVKFTAADFDKFCTVLTNAVCIPVQTDAVPYIMSTVSDTLLTPLHDGILDCMELIQKEATKPDSHISQLIPAIFRQLLIFSKFACAPPTFQQSVEHKYAKSSGHYANNASVEVVSMNYIPFGEKSISICVKLYQTTATEDSVVQEQILHDIVKALRTPLAMKYKCLSSSTWKLAISSLISVLHTGLKVARAKPQHFASLWDDLADTLDKFLFPASVCTIEDRGLEEIVLDETIDCQVIELLRDEVLPHSHEMPHQFIMQIVVLLNKGSIHSASDTNICYESDWKLREIFAKTCFETLLQFSLLEDHANTNNNRLNANVLTAGAAGAGGKDFAGRLAVTALLHRFQEVLKRFNDDERQSGKCPLPRFRLSEISFVLKAIATLVVSMKKAPASKVNKPAWDQLIGLYPYLVDCTTTTSPEVSRSLREALLQYTDLLQAPRSCSAATSNDNVIQSNGQE", "length": 1684 }, "evidence": [ { "id": "MGI:1914324", "url": "https://alliancegenome.org/gene/MGI:1914324#orthology", "database": "AGR" }, { "id": "HGNC:29177", "url": "https://alliancegenome.org/gene/HGNC:29177#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2712", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2712#orthology", "database": "AGR" }, { "id": "FB:FBgn0031985", "url": "https://alliancegenome.org/gene/FB:FBgn0031985#orthology", "database": "AGR" }, { "id": "RGD:1308808", "url": "https://alliancegenome.org/gene/RGD:1308808#orthology", "database": "AGR" }, { "id": "SGD:S000005241", "url": "https://alliancegenome.org/gene/SGD:S000005241#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6K6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1504, "end_pos": 1506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 412, "end_pos": 414, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 953, "end_pos": 955, "annotation": "n_glycosylation_sequon" }, { "start_pos": 964, "end_pos": 966, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P6K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6" }, { "id": "PF16206", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16206" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mon2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 924, "end_pos": 1702, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P6K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6" }, { "id": "PF09324", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09324" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mon2/Sec7/BIG1-like HDS", "eco_id": "ECO_0000259", "start_pos": 841, "end_pos": 920, "start_aa": "His", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P6K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6" }, { "id": "PF12783", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12783" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mon2/Sec7/BIG1-like HUS", "eco_id": "ECO_0000259", "start_pos": 216, "end_pos": 389, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P6K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6K6" }, { "id": "PF16213", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16213" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mon2/Sec7/BIG1-like dimerisation and cyclophilin-binding", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 187, "start_aa": "Ala", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 418 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1504, "end_pos": 1506 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 412, "end_pos": 414 }, { "start_pos": 461, "end_pos": 463 }, { "start_pos": 66, "end_pos": 68 }, { "start_pos": 953, "end_pos": 955 }, { "start_pos": 964, "end_pos": 966 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P152-1", "uniprot_ac": "A0A8M9P152", "uniprot_id": "A0A8M9P152_DANRE", "mass": { "chemical_mass": 58298.0, "monoisotopic_mass": 58298.0 }, "refseq": { "ac": "XP_021323362", "name": "sprouty-related, EVH1 domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323362" }, "gene_names": [ { "name": "spred3", "type": "recommended", "evidence": [ { "id": "A0A8M9P152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152" } ] }, { "name": "si:ch211-255l12.2", "type": "synonym", "evidence": [ { "id": "XP_021323362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323362" }, { "id": "A0A8M9P152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152" } ] }, { "name": "spred3", "type": "synonym", "evidence": [ { "id": "XP_021323362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323362" } ] } ], "protein_names": [ { "name": "Sprouty-related, EVH1 domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152/entry#names_and_taxonomy" } ] }, { "name": "sprouty-related, EVH1 domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323362", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323362" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323362", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323362" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P152", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "spred3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061207-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-31", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P152", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P152", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000040358", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000040358", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd10574", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10574", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "568925", "url": "https://www.ncbi.nlm.nih.gov/gene/568925", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000697", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000697", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:568925", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568925", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QFCARWA", "url": "https://omabrowser.org/oma/group/QFCARWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A140LGD0", "url": "https://www.orthodb.org/?gene=A0A140LGD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M1NF21", "url": "https://www.orthodb.org/?gene=A0A8M1NF21", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P152", "url": "https://www.orthodb.org/?gene=A0A8M9P152", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11202", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11202", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11202:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11202:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00568", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00568", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05210", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05210", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323362", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323362", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A140LGD0", "url": "https://www.uniprot.org/uniprotkb/A0A140LGD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140LGD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A140LGD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1NF21", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NF21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1NF21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NF21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P152", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P152-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HU86", "url": "https://www.uniprot.org/uniprotkb/A0AC58HU86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HU86-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HU86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061207-31", "url": "https://zfin.org/ZDB-GENE-061207-31", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMMLPVENGCCILEPIRNHMKVDRERQENESSEHKDVRVRAVVMTRDDSSGGWVPLGGGGLSHVIICKGRSSEGRGRREYVIRGERLRDRAPVLECAIQKGLVYNKVNPIFHHWRVEERKFGLTFQSPADAISFERGLQSVLEKLDRGSDSPSSSTPEEGDTEDDGQASHTGSESSSNSRKEMLPKPITIVTSESSSTCFVRPSEEFAYGNRTQTPAQIHTRPSQHQLTQVTAVLNPPSPPPPPPAPPTPPAAPPAASPLSPLSPTISLLEEGDLRSLDPCKDLWGTRGYEDYRRAGATRTKVGGLTGGVVVGGGQDKSELCVVRFEKELAGVGTTGCEVTVMLDTKGSQRNSSPTCMPNAVPGVPSASGSPQETGKSSPSPCCIHTSLATPRSRTRKRGAGGGEAISPDDDSSCPQGSSSCSSRCVYCRSVFSASENGRGRCRDAPDPALHCLRQWTCVWCAESLLYHCMSDSEGEFWEPCSCEDSMGGRPHPLCCARWMALLALSLFVPCMCCYLPLRACLRCGERCGCCGGKHKAVR", "length": 540, "header": "tr|A0A8M9P152-1|A0A8M9P152_DANRE Isoform 1 of Sprouty-related, EVH1 domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=spred3 PE=4 SV=1 CANONICAL=A0A8M9P152-1" }, "isoforms": [ { "isoform_ac": "A0A140LGD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152/entry#A0A140LGD0-1", "sequence": { "sequence": "MEGDVRVRAVVMTRDDSSGGWVPLGGGGLSHVIICKGRSSEGRGRREYVIRGERLRDRAPVLECAIQKGLVYNKVNPIFHHWRVEERKFGLTFQSPADAISFERGLQSVLEKLDRGSDSPSSSTPEEGDTEDDGQASHTGSESSSNSRKEMLPKPITIVTSESSSTCFVRPSEEFAYGNRTQTPAQIHTRPSQHQLTQVTAVLNPPSPPPPPPAPPTPPAAPPAASPLSPLSPTISLLEEGDLRSLDPCKDLWGTRGYEDYRRAGATRTKVGGLTGGVVVGGGQDKSELCVVRFEKELAGVGTTGCEVTVMLDTKGSQRNSSPTCMPNAVPGVPSASGSPQETGKSSPSPCCIHTSLATPRSRTRKRGAGGGEAISPDDDSSCPQGSSSCSSRCVYCRSVFSASENGRGRCRDAPDPALHCLRQWTCVWCAESLLYHCMSDSEGEFWEPCSCEDSMGGRPHPLCCARWMALLALSLFVPCMCCYLPLRACLRCGERCGCCGGKHKAVR", "length": 508, "header": "tr|A0A140LGD0-1|A0A8M9P152_DANRE Computationally mapped isoform of Sprouty-related, EVH1 domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=spred3 PE=4 SV=1 CANONICAL=A0A8M9P152-1" }, "locus": {} }, { "isoform_ac": "A0A8M1NF21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152/entry#A0A8M1NF21-1", "sequence": { "sequence": "MTVKHLSQSHTGSESSSNSRKEMLPKPITIVTSESSSTCFVRPSEEFAYGNRTQTPAQIHTRPSQHQLTQVTAVLNPPSPPPPPPAPPTPPAAPPAASPLSPLSPTISLLEEGDLRSLDPCKDLWGTRGYEDYRRAGATRTKVGGLTGGVVVGGGQDKSELCVVRFEKELAGVGTTGCEVTVMLDTKGSQRNSSPTCMPNAVPGVPSASGSPQETGKSSPSPCCIHTSLATPRSRTRKRGAGGGEAISPDDDSSCPQGSSSCSSRCVYCRSVFSASENGRGRCRDAPDPALHCLRQWTCVWCAESLLYHCMSDSEGEFWEPCSCEDSMGGRPHPLCCARWMALLALSLFVPCMCCYLPLRACLRCGERCGCCGGKHKAVR", "length": 380, "header": "tr|A0A8M1NF21-1|A0A8M9P152_DANRE Computationally mapped isoform of Sprouty-related, EVH1 domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=spred3 PE=4 SV=1 CANONICAL=A0A8M9P152-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P152-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152/entry#A0A8M9P152-1", "sequence": { "sequence": "MMMLPVENGCCILEPIRNHMKVDRERQENESSEHKDVRVRAVVMTRDDSSGGWVPLGGGGLSHVIICKGRSSEGRGRREYVIRGERLRDRAPVLECAIQKGLVYNKVNPIFHHWRVEERKFGLTFQSPADAISFERGLQSVLEKLDRGSDSPSSSTPEEGDTEDDGQASHTGSESSSNSRKEMLPKPITIVTSESSSTCFVRPSEEFAYGNRTQTPAQIHTRPSQHQLTQVTAVLNPPSPPPPPPAPPTPPAAPPAASPLSPLSPTISLLEEGDLRSLDPCKDLWGTRGYEDYRRAGATRTKVGGLTGGVVVGGGQDKSELCVVRFEKELAGVGTTGCEVTVMLDTKGSQRNSSPTCMPNAVPGVPSASGSPQETGKSSPSPCCIHTSLATPRSRTRKRGAGGGEAISPDDDSSCPQGSSSCSSRCVYCRSVFSASENGRGRCRDAPDPALHCLRQWTCVWCAESLLYHCMSDSEGEFWEPCSCEDSMGGRPHPLCCARWMALLALSLFVPCMCCYLPLRACLRCGERCGCCGGKHKAVR", "length": 540, "header": "tr|A0A8M9P152-1|A0A8M9P152_DANRE Isoform 1 of Sprouty-related, EVH1 domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=spred3 PE=4 SV=1 CANONICAL=A0A8M9P152-1" }, "locus": {} }, { "isoform_ac": "A0AC58HU86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152/entry#A0AC58HU86-1", "sequence": { "sequence": "MLPKPITIVTSESSSTCFVRPSEEFAYGNRTQTPAQIHTRPSQHQLTQVTAVLNPPSPPPPPPAPPTPPAAPPAASPLSPLSPTISLLEEGDLRSLDPCKDLWGTRGYEDYRRAGATRTKVGGLTGGVVVGGGQDKSELCVVRFEKELAGVGTTGCEVTVMLDTKGSQRNSSPTCMPNAVPGVPSASGSPQETGKSSPSPCCIHTSLATPRSRTRKRGAGGGEAISPDDDSSCPQGSSSCSSRCVYCRSVFSASENGRGRCRDAPDPALHCLRQWTCVWCAESLLYHCMSDSEGEFWEPCSCEDSMGGRPHPLCCARWMALLALSLFVPCMCCYLPLRACLRCGERCGCCGGKHKAVR", "length": 358, "header": "tr|A0AC58HU86-1|A0AC58HU86_DANRE Computationally mapped isoform of Sprouty-related, EVH1 domain-containing protein 3 isoform X4 OS=Danio rerio OX=7955 GN=spred3 PE=4 SV=1 CANONICAL=A0A8M9P152-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 249, "start_aa": "Thr", "end_pos": 249, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr249", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Crosstalk between Fgf and Wnt signaling in the zebrafish tailbud.", "journal": "Dev. Biol.", "date": "2012", "authors": "Stulberg Michael J, Lin Aiping, Zhao Hongyu, Holley Scott A", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1NF21", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NF21" } ], "reference": [ { "type": "PubMed", "id": "22796649", "url": "https://glygen.org/publication/PubMed/22796649" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1NF21", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NF21" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1NF21", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NF21" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "SPRED2 loss-of-function causes a recessive Noonan syndrome-like phenotype.", "journal": "Am. J. Hum. Genet.", "date": "2021", "authors": "Motta M, Fasano G, Gredy S, Brinkmann J, Bonnard AA, Simsek-Kiper PO, Gulec EY, Essaddam L, Utine GE, Guarnetti Prandi I, Venditti M, Pantaleoni F, Radio FC, Ciolfi A, Petrini S, Consoli F, Vignal C, Hepbasli D, Ullrich M, de Boer E, Vissers LELM, Gritli S, Rossi C, De Luca A, Ben Becher S, Gelb BD, Dallapiccola B, Lauri A, Chillemi G, Schuh K, Cave H, Zenker M, Tartaglia M", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1NF21", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NF21" } ], "reference": [ { "type": "PubMed", "id": "34626534", "url": "https://glygen.org/publication/PubMed/34626534" } ] } ], "pathway": [ { "id": "dre:568925", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568925", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KG11-1", "protein_name": "Sprouty-related protein with EVH-1 domain, isoform C", "gene_name": "Spred", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTEGHESDFLVTVRAQVMTRDESTEGWLPLAGGGLANVSIRKRARLSPLASGHDYIIYGQRISDQSVILSCVINRDLKYYKVMPTFHHWRAGKQRNGLTFQTAADARAFDKGVLRAYNELIDGLAKSNPTIICPPLTKYDSVGEDDVFMTLDLPVESESLQKIHSSPEGSEKSHKSVSNNSDSEKLPPPPIHYISTDKTSATTSPPDAPPASAAPSPATAGQIAASENYSYVTLTAVHHDYNYPVVDQPVGAQVLNARRESISALKKRNALEAAQAMAAAQTAAGGGLACRDGGSGKPLHKPNVSDILKKETRLRCRYCHELYSEDFNRRGACEYAPDAFRSGYECISGMGCARCMIYHCMSDAEGETAQHPCDCSASEAGCSKRWLGLAILSLFVPCLWCYPPLRACHLAGIHCGLCGGQHKPHVXHLEARLQGQHDDDPRPRSEFHYHHSEQSIMNSAKRPWGAKQKQSQQSQQSQRHFYNWELSHSLGAPQHQTPPYLMQSTGRKAPQNDYGRLLF", "length": 519 }, "evidence": [ { "id": "HGNC:31041", "url": "https://alliancegenome.org/gene/HGNC:31041#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-31#orthology", "database": "AGR" }, { "id": "MGI:2142186", "url": "https://alliancegenome.org/gene/MGI:2142186#orthology", "database": "AGR" }, { "id": "FB:FBgn0020767", "url": "https://alliancegenome.org/gene/FB:FBgn0020767#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A480KW66-1", "protein_name": "Sprouty related EVH1 domain containing 3", "gene_name": "SPRED3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKTTLECTLRPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALGRGSLTPSSSSSSSPSQDTAETPCPLTSHVDSDSSSSHSRQETPPSAAAAPIVTVESASGFGSATPPQRRRSSAQSYPPLLPFTGIPEPPEPLAGVGGPGWGGRGYEDYRRAGPPAPLALSTCVVRFAKTGALRGAALGSPAVLPAPLTEAAAPAPPARPPPGPGPASAPAKASPEAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLWCAESLLYHCLSDAEGDFSDPCACEPGHPRPAARWAALAALSLAVPCLCCYAPLRACHWVAARCGCAGCGGRHEEAAR", "length": 409 }, "evidence": [ { "id": "A0A8M9P152", "url": "https://omabrowser.org/oma/group/A0A8M9P152/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8N7T5I8-1", "protein_name": "Sprouty-related, EVH1 domain-containing protein 2", "gene_name": "spred2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTEESHPDDDSYIVRVKAVVMTRDESSGGWLAQEGGGLSRVGVCKVVPADLELLGRNGFLIFGERLKDKQMILQCFLKKDLVYTKATPTFHHWRVDNRKCGLSFQSPADARAFDRGVRKAIEDLTEGSTTSSSTLQNEAELGDDDVFTNATDSSSNSSQKRETSMQTLAPISFSEPHHCILGHLYDQHRHSDRYYLEQTVPMFQCSRHVRFHEEEEEIVRINPRERSWLTGYEDYRHATTATRTKPLRPDVTDAYVHLAKSEPPKHDYTYSYPLSGDGHVSRDGKTGIGGGVVTGQPRALTAKWLPRRVEDSRERLRCVYCQNMFSPSENGRGRCQEAPDPVQTCIRRVSFMWCADSLLYHCMSDPEGDYSDPCSCDASEERFCLRWLALLGLSLLAPCMCCYVPLRACYHCGVACHCCGGKHKATG", "length": 427 }, "evidence": [ { "id": "FB:FBgn0020767", "url": "https://alliancegenome.org/gene/FB:FBgn0020767#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LXY1-1", "protein_name": "Sprouty-related, EVH1 domain containing 3", "gene_name": "Spred3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAIGAVRCSSSRSLGPSGNVRPPCFYPSPKPPPPPHASSRFPLPPPSPRLPVPVSSAAGASQGAGANRRRRRRPRRRRSEPGRSLPGRYMVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKTTLECTLRPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLQAALAALSRGSLTPSSSSSSSSPSRDTAETPCPLTSHVDSDSSSSHSRQETPPTAVAPIATVESATAFPPATPPQRRRSSAQSYPPLLPFTGIPEPSESLAGAGSQGRGGRGYEDYRRSGPPPPPLALSTCVVRFAKTGALRGAALGPPVSLPAPLTEAAPPALPARPPPGPGPTPAPAKASPEAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLWCAESLLYHCLSDAEGDFSDPCACEPGHPRPAARWAALAALSLAVPCLCCYAPLRACHWVAARCGCAGCGGRHEEAAR", "length": 500 }, "evidence": [ { "id": "HGNC:31041", "url": "https://alliancegenome.org/gene/HGNC:31041#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-31#orthology", "database": "AGR" }, { "id": "MGI:2142186", "url": "https://alliancegenome.org/gene/MGI:2142186#orthology", "database": "AGR" }, { "id": "RGD:1311713", "url": "https://alliancegenome.org/gene/RGD:1311713#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2MJR0-1", "protein_name": "Sprouty-related, EVH1 domain-containing protein 3", "gene_name": "SPRED3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKTTLECTLKPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALGRGSLTPSSSSSSSSPSQDTAETPCPLTSHVDSDSSSSHSRQETPPSAAAAPIITMESASGFGPTTPPQRRRSSAQSYPPLLPFTGIPEPSEPLAGAGGLGWGGRGYEDYRRSGPPAPLALSTCVVRFAKTGALRGAALGPPAALPAPLTEAAPPAPPARPPPGPGPSSAPAKASPEAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLWCAESLLYHCLSDAEGDFSDPCACEPGHPRPAARWAALAALSLAVPCLCCYAPLRACHWVAARCGCAGCGGRHEEAAR", "length": 410 }, "evidence": [ { "id": "HGNC:31041", "url": "https://alliancegenome.org/gene/HGNC:31041#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-31#orthology", "database": "AGR" }, { "id": "MGI:2142186", "url": "https://alliancegenome.org/gene/MGI:2142186#orthology", "database": "AGR" }, { "id": "FB:FBgn0020767", "url": "https://alliancegenome.org/gene/FB:FBgn0020767#orthology", "database": "AGR" }, { "id": "RGD:1311713", "url": "https://alliancegenome.org/gene/RGD:1311713#orthology", "database": "AGR" }, { "id": "A0A8M9P152", "url": "https://omabrowser.org/oma/group/A0A8M9P152/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3C2P8-1", "protein_name": "Sprouty-related, EVH1 domain-containing protein 2", "gene_name": "Spred2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREPNTRTISSPTSCEHRRIYTLDPYPMDLYHPDQRLPRSYPQVTFPEDDEEIVRINPREKIWMTGYEDYRHAPVRGKYLDSTEDADSYVRFAKGEVPKHEYTYPYVDSSDFGFGEDPKGNVIKTQPPRAKSRRRKENGERSRCVYCRDMFNHEENRRGHCQDAPDAVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACHHCGVMCRCCGGKHKAAA", "length": 410 }, "evidence": [ { "id": "FB:FBgn0020767", "url": "https://alliancegenome.org/gene/FB:FBgn0020767#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6NYK3-1", "protein_name": "Sprouty-related, EVH1 domain-containing protein 2", "gene_name": "spred2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIEETHPNDDSYIVRVKAVVMTRDDSSGGWLAQEGGGLSRVGVCKVMPAELTGRSDFLIHGERLKDKQVILECFVRKDLIYTKATPTFHHWKVDNKKCGLTFQSPADARAFDRGVRKALEDLTEGSTTSSSTLQNEAELGDDDVFTTATDSSSNSSQKKDHSTQLVATSTFYEPHPHRCILQYRPPERYTLDQKFSRNLFPFEDEEIVRINPRERWMITGYEDYRYAAVPDKFIQPEDSDSYVQISKNDPVKHDYTYPYVPSPDFTQCDLKRPCGGGSTVVSTQPRAFILKGKRRKEDGERSRCVYCRDMFNHEENRRGQCHDAPDPIRTCIHRVSFMWCADSMLYHCMSDPEGDYSDPCSCDTSEERFCLRWTALLGLAMLAPCLCCYPPLHGCHRCGVACGCCGGKHKAVG", "length": 413 }, "evidence": [ { "id": "FB:FBgn0020767", "url": "https://alliancegenome.org/gene/FB:FBgn0020767#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6P6N5-1", "protein_name": "Sprouty-related, EVH1 domain-containing protein 3", "gene_name": "Spred3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRVRAVVMARDDSSGGWLPVGGGGLSQVSVCRVRGARPEGGARQGHYVIHGERLRDQKTTLECTLRPGLVYNKVNPIFHHWSLGDCKFGLTFQSPAEADEFQKSLLAALAALSRGSLTPSSSSSSSSPSQDTAETPCPLTSHVDSDSSSSHSRQETPPTAPIATVESAAAFPLATRPQRRRSSAQSYPPLLPFTGIPEPSESLAGAGSQGWGSRGYEDYRRSGPPPPPLALSTCVVRFAKTGALRGAALGPPVSLPAPLTEAAPPAPPARPPPGPGPTPAPAKASPEAEEAARCVHCRALFRRRADGRGGRCAEAPDPGRLLVRRLSCLWCAESLLYHCLSDAEGDFSDPCACEPGHPRPAARWAALAALSLAVPCLCCYAPLRACHWVAARCGCAGCGGRHEEAAR", "length": 408 }, "evidence": [ { "id": "HGNC:31041", "url": "https://alliancegenome.org/gene/HGNC:31041#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-31#orthology", "database": "AGR" }, { "id": "MGI:2142186", "url": "https://alliancegenome.org/gene/MGI:2142186#orthology", "database": "AGR" }, { "id": "FB:FBgn0020767", "url": "https://alliancegenome.org/gene/FB:FBgn0020767#orthology", "database": "AGR" }, { "id": "RGD:1311713", "url": "https://alliancegenome.org/gene/RGD:1311713#orthology", "database": "AGR" }, { "id": "A0A8M9P152", "url": "https://omabrowser.org/oma/group/A0A8M9P152/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z698-1", "protein_name": "Sprouty-related, EVH1 domain-containing protein 2", "gene_name": "SPRED2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTIHNEAELGDDDVFTTATDSSSNSSQKREQPTRTISSPTSCEHRRIYTLGHLHDSYPTDHYHLDQPMPRPYRQVSFPDDDEEIVRINPREKIWMTGYEDYRHAPVRGKYPDPSEDADSSYVRFAKGEVPKHDYNYPYVDSSDFGLGEDPKGRGGSVIKTQPSRGKSRRRKEDGERSRCVYCRDMFNHEENRRGHCQDAPDSVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACYHCGVMCRCCGGKHKAAA", "length": 418 }, "evidence": [ { "id": "FB:FBgn0020767", "url": "https://alliancegenome.org/gene/FB:FBgn0020767#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7Z699-1", "protein_name": "Sprouty-related, EVH1 domain-containing protein 1", "gene_name": "SPRED1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEETATSDNDNSYARVRAVVMTRDDSSGGWLPLGGSGLSSVTVFKVPHQEENGCADFFIRGERLRDKMVVLECMLKKDLIYNKVTPTFHHWKIDDKKFGLTFQSPADARAFDRGIRRAIEDISQGCPESKNEAEGADDLQANEEDSSSSLVKDHLFQQETVVTSEPYRSSNIRPSPFEDLNARRVYMQSQANQITFGQPGLDIQSRSMEYVQRQISKECGSLKSQNRVPLKSIRHVSFQDEDEIVRINPRDILIRRYADYRHPDMWKNDLERDDADSSIQFSKPDSKKSDYLYSCGDETKLSSPKDSVVFKTQPSSLKIKKSKRRKEDGERSRCVYCQERFNHEENVRGKCQDAPDPIKRCIYQVSCMLCAESMLYHCMSDSEGDFSDPCSCDTSDDKFCLRWLALVALSFIVPCMCCYVPLRMCHRCGEACGCCGGKHKAAG", "length": 444 }, "evidence": [ { "id": "FB:FBgn0020767", "url": "https://alliancegenome.org/gene/FB:FBgn0020767#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q924S7-1", "protein_name": "Sprouty-related, EVH1 domain-containing protein 2", "gene_name": "Spred2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEETHPDDDSYIVRVKAVVMTRDDSSGGWFPQEGGGISRVGVCKVMHPEGNGRSGFLIHGERQKDKLVVLECYVRKDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDLIEGSTTSSSTLHNEAELGDDDVFTTATDSSSNSSQKREPTTRTISSPTSCEHRKIYTLDPYPMDHYHPDQRLPRSYPQVTFPEDDEEIVRINPREKIWMTGYEDYRHAPVRGKYLDTTEDADSYVRFAKGEVPKHEYTYPYVDSSDFGFGEDPKGSVIKTQPPRAKSRRRKENGERSRCVYCRDMFNHEENRRGHCQDAPDAVRTCIRRVSCMWCADSMLYHCMSDPEGDYTDPCSCDTSDEKFCLRWMALIALSFLAPCMCCYLPLRACHRCGVMCRCCGGKHKAAA", "length": 410 }, "evidence": [ { "id": "FB:FBgn0020767", "url": "https://alliancegenome.org/gene/FB:FBgn0020767#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S8-1", "protein_name": "Sprouty-related, EVH1 domain-containing protein 1", "gene_name": "Spred1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEETATSDNDNSYARVRAVVMTRDDSSGGWLPLGGSGLSSVTVFRVPHQEENGCADFFIRGERLRDKMVVLECMLKKDLIYNKVTPTFHHWKIDDKKFGLTFQSPADARAFDRGIRRAIEDISLGCPASKTEAEGGDDDLQTTEEDTSRSLVKDHFFQQETVVTSEPYRSSDIRPLPFEDLNARRVYLQSQVSQIPFSQQGLDIQSRSMEYVQRQISKECGSLKSQTRVPLKSIRHVSFQDEDEIVRINPRDILIRRYADYRHPDMWKNDLERDDTDSSVPFSKQDSKKSDYLYHCGDETKLSSLKDSVVFKTQPPSLKFKSKRRKEDGERSRCVYCQERFNHEENARGKCQDAPDPVKRCIYQVSCMLCAESMLYHCMSDSEGDFSDPCSCDTSDDKFCLRWLALVALSFIVPCMCCYVPLRMCHRCGEACGCCGGKHKAAG", "length": 444 }, "evidence": [ { "id": "FB:FBgn0020767", "url": "https://alliancegenome.org/gene/FB:FBgn0020767#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of intracellular signal transduction", "id": "GO:1902532", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902532", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P152", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152" } ], "pmid": "" }, { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P152", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152" } ], "pmid": "" }, { "name": "negative regulation of ERK1 and ERK2 cascade", "id": "GO:0070373", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070373", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P152", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P152", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P152", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P152", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152" }, { "id": "PS51488", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51488" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KBD", "eco_id": "ECO_0000259", "start_pos": 263, "end_pos": 329, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P152", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P152" }, { "id": "PS50229", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50229" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WH1", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 145, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 249 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 352, "end_pos": 354 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PF81-1", "uniprot_ac": "A0A8M9PF81", "uniprot_id": "A0A8M9PF81_DANRE", "mass": { "chemical_mass": 28669.0, "monoisotopic_mass": 28669.0 }, "refseq": { "ac": "XP_021325548", "name": "tumor protein p53-inducible nuclear protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325548" }, "gene_names": [ { "name": "tp53inp2b", "type": "recommended", "evidence": [ { "id": "A0A8M9PF81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81" } ] }, { "name": "tp53inp2b", "type": "synonym", "evidence": [ { "id": "XP_021325548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325548" } ] } ], "protein_names": [ { "name": "Tumor protein p53-inducible nuclear protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PF81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81/entry#names_and_taxonomy" } ] }, { "name": "tumor protein p53-inducible nuclear protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325548", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325548" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325548.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325548", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325548" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tp53inp2b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-250331-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-250331-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PF81", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PF81", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000109769", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000109769", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "569441", "url": "https://www.ncbi.nlm.nih.gov/gene/569441", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569441", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569441", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HQGSFIY", "url": "https://omabrowser.org/oma/group/HQGSFIY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PF81", "url": "https://www.orthodb.org/?gene=A0A8M9PF81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31671", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31671", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31671:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31671:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14839", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14839", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325548", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325548", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A2R8Q3N4", "url": "https://www.uniprot.org/uniprotkb/A0A2R8Q3N4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2R8Q3N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A2R8Q3N4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PF81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PF81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PKX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PKX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32THG3", "url": "https://www.uniprot.org/uniprotkb/A0AB32THG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32THG3-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32THG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-250331-1", "url": "https://zfin.org/ZDB-GENE-250331-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFQALSSLFFGSVDDVTPELKGPKPCVTEADEEGWLLVNLPGEDGPEAASVACARPRSECHASPPTCKNRRSRAGRTQATPPLSTCSAPDPASFSHLESVEVNVLLSERGSCSCSDCSMDESWFVTPPPCFTAEGATAEASPMEDLLIEHPSMSVYVSPGPLPAMEESATSLAGSISRMSESALPAVTRSSLPTRVTRGAAAQAGALAKVTQVSRVQRAKARTERRHLGRNRMQRQNRVREQVQRRATHTRNSFLHQPCQRNICH", "length": 265, "header": "tr|A0A8M9PF81-1|A0A8M9PF81_DANRE Isoform 1 of Tumor protein p53-inducible nuclear protein 2 isoform X1 OS=Danio rerio OX=7955 GN=tp53inp2b PE=4 SV=2 CANONICAL=A0A8M9PF81-1" }, "isoforms": [ { "isoform_ac": "A0A2R8Q3N4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81/entry#A0A2R8Q3N4-1", "sequence": { "sequence": "MFQALSSLFFGSVDDVTPELKGPKPCVTEADEEGWLLVNLPEGATAEASPMEDLLIEHPSMSVYVSPGPLPAMEESATSLAGSISRMSESALPAVTRSSLPTRVTRGAAAQAGALAKVTQVSRVQRAKARTERRHLGRNRMQRQNRVREQVQRRATHTRNSFLHQPCQRNICH", "length": 173, "header": "tr|A0A2R8Q3N4-1|A0A8M9PF81_DANRE Computationally mapped isoform of Tumor protein p53-inducible nuclear protein 2 isoform X1 OS=Danio rerio OX=7955 GN=tp53inp2b PE=4 SV=1 CANONICAL=A0A8M9PF81-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PF81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81/entry#A0A8M9PF81-1", "sequence": { "sequence": "MFQALSSLFFGSVDDVTPELKGPKPCVTEADEEGWLLVNLPGEDGPEAASVACARPRSECHASPPTCKNRRSRAGRTQATPPLSTCSAPDPASFSHLESVEVNVLLSERGSCSCSDCSMDESWFVTPPPCFTAEGATAEASPMEDLLIEHPSMSVYVSPGPLPAMEESATSLAGSISRMSESALPAVTRSSLPTRVTRGAAAQAGALAKVTQVSRVQRAKARTERRHLGRNRMQRQNRVREQVQRRATHTRNSFLHQPCQRNICH", "length": 265, "header": "tr|A0A8M9PF81-1|A0A8M9PF81_DANRE Isoform 1 of Tumor protein p53-inducible nuclear protein 2 isoform X1 OS=Danio rerio OX=7955 GN=tp53inp2b PE=4 SV=2 CANONICAL=A0A8M9PF81-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PKX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81/entry#A0A8M9PKX0-1", "sequence": { "sequence": "MFQALSSLFFGSVDDVTPELKGPKPCVTEADEEGWLLVNLPGEDGPEAASVACARPRSECHASPPTCKNRRSRAGRTQATPPLSTCSAPDPASFSHLESVEVNVLLSERGSCSCSDCSMDESWFVTPPPCFTAEGATAEASPMEDLLIEHPSMSVYVSPGPLPAMEESATSLAGSIRMSESALPAVTRSSLPTRVTRGAAAQAGALAKVTQVSRVQRAKARTERRHLGRNRMQRQNRVREQVQRRATHTRNSFLHQPCQRNICH", "length": 264, "header": "tr|A0A8M9PKX0-1|A0A8M9PKX0_DANRE Computationally mapped isoform of Tumor protein p53-inducible nuclear protein 2 isoform X2 OS=Danio rerio OX=7955 GN=tp53inp2b PE=4 SV=2 CANONICAL=A0A8M9PF81-1" }, "locus": {} }, { "isoform_ac": "A0AB32THG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81/entry#A0AB32THG3-1", "sequence": { "sequence": "MFQALSSLFFGSVDDVTPELKGPKPCVTEADEEGWLLVNLPEGATAEASPMEDLLIEHPSMSVYVSPGPLPAMEESATSLAGSIRMSESALPAVTRSSLPTRVTRGAAAQAGALAKVTQVSRVQRAKARTERRHLGRNRMQRQNRVREQVQRRATHTRNSFLHQPCQRNICH", "length": 172, "header": "tr|A0AB32THG3-1|A0A8M9PF81_DANRE Computationally mapped isoform of Tumor protein p53-inducible nuclear protein 2 isoform X1 OS=Danio rerio OX=7955 GN=tp53inp2b PE=4 SV=1 CANONICAL=A0A8M9PF81-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 197, "start_aa": "Thr", "end_pos": 197, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr197", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:569441", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569441", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1B8N8-1", "protein_name": "Tumor protein p53 inducible nuclear protein 2", "gene_name": "TP53INP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLQRLTSLFFSPPPPAAEDPDCSQAFVSEEDEVDGWLIIDLPDSFTAPPSPGAAAAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLESGPPSPHPEDDEAALPDGDSSDGELAPARREARALHHAAPLPARAALLEKAGQARRVQRARQRAERHALSAKVVQRQNRARESRPRRPKHQGSFVYQPCQRQFNY", "length": 224 }, "evidence": [ { "id": "A0A8M9PF81", "url": "https://omabrowser.org/oma/group/A0A8M9PF81/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HAP3-1", "protein_name": "Tumor protein p53-inducible nuclear protein 2 isoform X1", "gene_name": "Tp53inp2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFQRFTSLFFSTPSPPEDSNCPGAFVSEEDEVDGWLIIGLQDSYTAPPNPGASPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSNPLEDLLIEHPSMSVYVTGSTIVLESGPPSPHPDAVLPEEDLSDGELAPARREPRALHHAAAAALPARAALLEKAGQVRRLQRARQRAERHALSAKVLQRQNRARESRSRKPKHQGSFIYQPCQRQFNY", "length": 222 }, "evidence": [ { "id": "A0A8M9PF81", "url": "https://omabrowser.org/oma/group/A0A8M9PF81/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3LVN2-1", "protein_name": "Tumor protein p53 inducible nuclear protein 2", "gene_name": "TP53INP2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFQRFTSLFFSTPAPPEDPNCPRAFVSEEDEVDGWLIIDLPDSFTASPSPGAAPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLEPGPPSPHPDAALPDGNLSDGELAPAHREPRALHHAAAPLPARAALLEKAGQARRLQRARQRAERHALSAKVVQRQNRARESRPRRPKHQGSFVYQPCQRQFNY", "length": 221 }, "evidence": [ { "id": "A0A8M9PF81", "url": "https://omabrowser.org/oma/group/A0A8M9PF81/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8CFU8-1", "protein_name": "Tumor protein p53-inducible nuclear protein 2", "gene_name": "Tp53inp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQRFTSLFFNTPAPPEDSNCPGAFVSEEDEVDGWLIIDLQDSYTAPPDPGASPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSNPLEDLLIEHPSMSVYVTGSTIVLESGPPSPHPEAALPDQDLSDGELAPALREPRALHHAAAPMPARAVLLEKAGQVRRLQRARQRAERHTLSAKVLQRQNRARESRSRRPKHQGSFIYQPCQRQFNY", "length": 221 }, "evidence": [ { "id": "A0A8M9PF81", "url": "https://omabrowser.org/oma/group/A0A8M9PF81/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CHM3-1", "protein_name": "Tumor protein p53-inducible nuclear protein 2", "gene_name": "Tp53inp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQRFTSLFFSTPAPPEDSNCPGAFVSEEDEVDGWLIIDLQDSYTAPPDPRASPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSNPLEDLLIEHPSMSVYVTGSTIVLESGPPSPHPEAALPDQDLSDGELAPARREPRALHHAAAPMPARAVLLEKAGQVRRLQRARQRAERHTLSAKVLQRQNRARES", "length": 199 }, "evidence": [ { "id": "A0A8M9PF81", "url": "https://omabrowser.org/oma/group/A0A8M9PF81/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IXH6-1", "protein_name": "Tumor protein p53-inducible nuclear protein 2", "gene_name": "TP53INP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFQRLSSLFFSTPSPPEDPDCPRAFVSEEDEVDGWLIIDLPDSYAAPPSPGAAPAPAGRPPPAPSLMDESWFVTPPACFTAEGPGLGPARLQSSPLEDLLIEHPSMSVYVTGSTIVLEPGSPSPLPDAALPDGDLSEGELTPARREPRAARHAAPLPARAALLEKAGQVRRLQRARQRAERHALSAKAVQRQNRARESRPRRSKNQSSFIYQPCQRQFNY", "length": 220 }, "evidence": [ { "id": "A0A8M9PF81", "url": "https://omabrowser.org/oma/group/A0A8M9PF81/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "autophagosome assembly", "id": "GO:0000045", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000045", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81" } ], "pmid": "" }, { "name": "autophagy", "id": "GO:0006914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006914", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81" } ], "pmid": "" }, { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81" } ], "pmid": "" }, { "name": "autophagosome", "id": "GO:0005776", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005776", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 197 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PC45-1", "uniprot_ac": "A0A8M9PC45", "uniprot_id": "A0A8M9PC45_DANRE", "mass": { "chemical_mass": 80090.0, "monoisotopic_mass": 80090.0 }, "refseq": { "ac": "XP_021321964", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321964" }, "gene_names": [ { "name": "zgc:162962", "type": "synonym", "evidence": [ { "id": "XP_021321964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321964" }, { "id": "A0A8M9PC45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PC45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021321964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321964" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021321964.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021321964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321964" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC45", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A2R8RUY8", "url": "https://www.uniprot.org/uniprotkb/A0A2R8RUY8#function" }, { "database": "UniProtKB", "id": "A0A2R8Q532", "url": "https://www.uniprot.org/uniprotkb/A0A2R8Q532#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC45", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070424-76", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-76", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PC45", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PC45", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000116765", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000116765", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "798203", "url": "https://www.ncbi.nlm.nih.gov/gene/798203", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:798203", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798203", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AHNFNSH", "url": "https://omabrowser.org/oma/group/AHNFNSH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A2R8Q532", "url": "https://www.orthodb.org/?gene=A0A2R8Q532", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A2R8RUY8", "url": "https://www.orthodb.org/?gene=A0A2R8RUY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PC45", "url": "https://www.orthodb.org/?gene=A0A8M9PC45", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF114", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF114", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021321964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321964", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A2R8Q532", "url": "https://www.uniprot.org/uniprotkb/A0A2R8Q532", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2R8Q532-1", "url": "https://www.uniprot.org/uniprotkb/A0A2R8Q532-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2R8RUY8", "url": "https://www.uniprot.org/uniprotkb/A0A2R8RUY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2R8RUY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A2R8RUY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PC45", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PC45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070424-76", "url": "https://zfin.org/ZDB-GENE-070424-76", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEKMDFIIVEIDDLSDPEPSRINHEDNKEQTDWMELNEQRQDLTEEDEKCDFNTEGIKAEHLHSCPQCGKSFTSKENLNMHMNIHSEENLYICTECGKSFSQLDSYNLHQNTHNEARDHVCLECGKSFSTADNLKRHRIIHAGEKPHKCSYCEKSFNQSVHLRRHERIHTGEKPYLCTHCGESFRYRTDLNKHLRVHTGETPFTCEQCGNNFRSSANLKLHMTIHTNEKPYACPLCQRRFSRLNACQRHQKIHVEEKNHVCLECGKSFIRAEQLKNHQRIHTGEKPYKCSYCEKSFSWSSNLKLHERVHTGEKPYYCPACQKSFRSSQNLLNHTRKCHTITEIKMEFVEEEIDDLGDSETSRIYKQEETEEQTDLKEVKQENLELNEDEDFLHGEPENNSQTTDTKNSFSCPHCDRSFTLEASLISHSSIHSRERPYTCPQCPKSFARKDSLRMHLRLHTGEKPYACPQCAKAFAQKEHLTIHIRIHTGEKPFVCDQCGSSFARSDSLKNHSRIHTGVKPYSCPHCAKRFTWLHNFRKHIRLHSGVKPYSCEDCGKKFPSASVLKYHIQSHSEERPHSCSTCGKSFIQLDAFKMHQKLHSGVRPFVCSHCGKSFNKASNLTEHFRIHTGEKPYTCSLCGKSFTHSATLKAHERIHTGEKPHHCTQCGKSFGRASHLLAHVKTHSSKRKTSQ", "length": 691, "header": "tr|A0A8M9PC45-1|A0A8M9PC45_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN= PE=3 SV=2 CANONICAL=A0A8M9PC45-1" }, "isoforms": [ { "isoform_ac": "A0A2R8Q532-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45/entry#A0A2R8Q532-1", "sequence": { "sequence": "MRQKEIKMEFVEEEIDDLGDSETSRIYKQEETEEQTDPKEVKQENLELNEDEDFLHGEPENNSQTTDTKNSFSCPHCDRSFTLEASLISHSSIHSRERPYTCPQCPKSFARKDSLRMHLRLHTGEKPYACPQCAKAFAQKEHLTIHIRIHTGEKPFVCDQCGSSFARSDSLKNHSRIHTGVKPYSCPHCAKRFTWLHNFRKHIRLHSGVKPYSCEDCGKKFPSASVLKYHMQSHSEERPHSCSTCGKSFIQLDAFKMHQKLHSGVRPFVCSHCGKSFNKASNLTEHFRIHTGEKPYTCSLCGKSFTHSATLKAHERIHTGEKPHHCTQCGKSFGRASHLLAHVKTHSSKRKTSQ", "length": 354, "header": "tr|A0A2R8Q532-1|A0A8M9PC45_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=A0A8M9PC45-1" }, "locus": {} }, { "isoform_ac": "A0A2R8RUY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45/entry#A0A2R8RUY8-1", "sequence": { "sequence": "MEFVEEEIDDLGDSETSRIYKQEETEEQTDPKEVKQENLELNEDEDFLHGEPENNSQTTDTKNSFSCPHCDRSFTLEASLISHSSIHSRERPYTCPQCPKSFARKDSLRMHLRLHTGEKPYACPQCAKAFAQKEHLTIHIRIHTGEKPFVCDQCGSSFARSDSLKNHSRIHTGVKPYSCPHCAKRFTWLHNFRKHIRLHSGVKPYSCEDCGKKFPSASVLKYHMQSHSEERPHSCSTCGKSFIQLDAFKMHQKLHSGVRPFVCSHCGKSFNKASNLTEHFRIHTGEKPYTCSLCGKSFTHSATLKAHERIHTGEKPHHCTQCGKSFGRASHLLAHVKTHSSKRKTSQ", "length": 347, "header": "tr|A0A2R8RUY8-1|A0A8M9PC45_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=A0A8M9PC45-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PC45-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45/entry#A0A8M9PC45-1", "sequence": { "sequence": "MEKMDFIIVEIDDLSDPEPSRINHEDNKEQTDWMELNEQRQDLTEEDEKCDFNTEGIKAEHLHSCPQCGKSFTSKENLNMHMNIHSEENLYICTECGKSFSQLDSYNLHQNTHNEARDHVCLECGKSFSTADNLKRHRIIHAGEKPHKCSYCEKSFNQSVHLRRHERIHTGEKPYLCTHCGESFRYRTDLNKHLRVHTGETPFTCEQCGNNFRSSANLKLHMTIHTNEKPYACPLCQRRFSRLNACQRHQKIHVEEKNHVCLECGKSFIRAEQLKNHQRIHTGEKPYKCSYCEKSFSWSSNLKLHERVHTGEKPYYCPACQKSFRSSQNLLNHTRKCHTITEIKMEFVEEEIDDLGDSETSRIYKQEETEEQTDLKEVKQENLELNEDEDFLHGEPENNSQTTDTKNSFSCPHCDRSFTLEASLISHSSIHSRERPYTCPQCPKSFARKDSLRMHLRLHTGEKPYACPQCAKAFAQKEHLTIHIRIHTGEKPFVCDQCGSSFARSDSLKNHSRIHTGVKPYSCPHCAKRFTWLHNFRKHIRLHSGVKPYSCEDCGKKFPSASVLKYHIQSHSEERPHSCSTCGKSFIQLDAFKMHQKLHSGVRPFVCSHCGKSFNKASNLTEHFRIHTGEKPYTCSLCGKSFTHSATLKAHERIHTGEKPHHCTQCGKSFGRASHLLAHVKTHSSKRKTSQ", "length": 691, "header": "tr|A0A8M9PC45-1|A0A8M9PC45_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN= PE=3 SV=2 CANONICAL=A0A8M9PC45-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A2R8Q532", "url": "https://www.uniprot.org/uniprotkb/A0A2R8Q532" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:798203", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798203", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC45", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC45", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC45", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC45", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC45", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC45", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC45", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC45", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC45", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC45" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 398, "end_pos": 400, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": 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"uniprot_canonical_ac": "A0A8M9P5U3-1", "uniprot_ac": "A0A8M9P5U3", "uniprot_id": "A0A8M9P5U3_DANRE", "mass": { "chemical_mass": 39099.0, "monoisotopic_mass": 39099.0 }, "refseq": { "ac": "XP_073796355", "name": "enoyl-CoA delta isomerase 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073796355" }, "gene_names": [ { "name": "eci2", "type": "recommended", "evidence": [ { "id": "A0A8M9P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ] }, { "name": "PECI", "type": "synonym", "evidence": [ { "id": "XP_073796355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073796355" }, { "id": "A0A8M9P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ] }, { "name": "eci2", "type": "synonym", "evidence": [ { "id": "XP_073796355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073796355" } ] }, { "name": "fd61c12", "type": "synonym", "evidence": [ { "id": "XP_073796355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073796355" }, { "id": "A0A8M9P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ] }, { "name": "wu:fd61c12", "type": "synonym", "evidence": [ { "id": "XP_073796355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073796355" }, { "id": "A0A8M9P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ] }, { "name": "zgc:175023", "type": "synonym", "evidence": [ { "id": "XP_073796355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073796355" }, { "id": "A0A8M9P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ] }, { "name": "zgc:92030", "type": "synonym", "evidence": [ { "id": "XP_073796355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073796355" }, { "id": "A0A8M9P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ] } ], "protein_names": [ { "name": "Enoyl-CoA delta isomerase 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3/entry#names_and_taxonomy" } ] }, { "name": "enoyl-CoA delta isomerase 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_073796355", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073796355" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073796355", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073796355" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "eci2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040718-392", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-392", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P5U3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P5U3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00435", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00435", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06558", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06558", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "436918", "url": "https://www.ncbi.nlm.nih.gov/gene/436918", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000582", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000582", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022408", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022408", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029045", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029045", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:436918", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:436918", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M1N0S4", "url": "https://www.orthodb.org/?gene=A0A8M1N0S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43684", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43684", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43684:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43684:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00378", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00378", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00887", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00887", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073796355", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073796355", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M1N0S4", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N0S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1N0S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N0S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P5U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P5U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040718-392", "url": "https://zfin.org/ZDB-GENE-040718-392", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGASVEDFNKAKDKLNTLKKDPGNEVKLKIYALFKQATVGPCNTPKPGMLDFVNKVKWDAWKGLGSISQEDARQQYVDLISSLVGAEAPAVAAQPTGGGKTFQTLLVSTEDNITTIRLNRPDKKNAITVEMYNELIEALELAGKDDSVITVMTGNGDYYCSGNDLNNFTKIPEGGVEKMAKDAGELLRRYVKAYIDFPKPLIGVINGPAVGVSVTLLGLFDVVYATEKATFHTPFSQLGQSPEGCSSYLFPKMMGAAKASEVLLFNKKLSATQACELGLVSEVFPESSFQSEVWSRLKAYAKLPKNSLALSKQLIRGLEKEKLHAVNDAEVERLTERWLSDECMQAIMSFFQGKSKL", "length": 357, "header": "tr|A0A8M9P5U3-1|A0A8M9P5U3_DANRE Isoform 1 of Enoyl-CoA delta isomerase 2 isoform X1 OS=Danio rerio OX=7955 GN=eci2 PE=1 SV=2 CANONICAL=A0A8M9P5U3-1" }, "isoforms": [ { "isoform_ac": "A0A8M1N0S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3/entry#A0A8M1N0S4-1", "sequence": { "sequence": "MASLIKHVSPWRFARFVRSSKTAFIPCVQLHSTAVMGASVEDFNKAKDKLNTLKKDPGNEVKLKIYALFKQATVGPCNTPKPGMLDFVNKVKWDAWKGLGSISQEEARQQYVDLISSLVGAEAPAVAAQPTGGGKTFQTLLVSTEDNITTIRLNRPDKKNAITVEMYNELIEALELAGKDDSVITVMTGNGDYYCSGNDLNNFTKIPEGGVEKMAKDAGELLRRYVKAYIDFPKPLIGVINGPAVGVSVTLLGLFDVVYATEKATFHTPFSQLGQSPEGCSSYLFPKMMGAAKASEVLLFNKKLSATQACELGLVSEVFPESSFQSEVWSRLKAYAKLPKNSLALSKQLIRGLEKEKLHAVNDAEVERLTERWLSDECMQAIMSFFQGKSKL", "length": 392, "header": "tr|A0A8M1N0S4-1|A0A8M9P5U3_DANRE Computationally mapped isoform of Enoyl-CoA delta isomerase 2 isoform X1 OS=Danio rerio OX=7955 GN=eci2 PE=1 SV=2 CANONICAL=A0A8M9P5U3-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P5U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3/entry#A0A8M9P5U3-1", "sequence": { "sequence": "MGASVEDFNKAKDKLNTLKKDPGNEVKLKIYALFKQATVGPCNTPKPGMLDFVNKVKWDAWKGLGSISQEDARQQYVDLISSLVGAEAPAVAAQPTGGGKTFQTLLVSTEDNITTIRLNRPDKKNAITVEMYNELIEALELAGKDDSVITVMTGNGDYYCSGNDLNNFTKIPEGGVEKMAKDAGELLRRYVKAYIDFPKPLIGVINGPAVGVSVTLLGLFDVVYATEKATFHTPFSQLGQSPEGCSSYLFPKMMGAAKASEVLLFNKKLSATQACELGLVSEVFPESSFQSEVWSRLKAYAKLPKNSLALSKQLIRGLEKEKLHAVNDAEVERLTERWLSDECMQAIMSFFQGKSKL", "length": 357, "header": "tr|A0A8M9P5U3-1|A0A8M9P5U3_DANRE Isoform 1 of Enoyl-CoA delta isomerase 2 isoform X1 OS=Danio rerio OX=7955 GN=eci2 PE=1 SV=2 CANONICAL=A0A8M9P5U3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "A0A8M9P5U3", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M9P5U3" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1N0S4", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N0S4" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Insights Into the Peroxisomal Protein Inventory of Zebrafish.", "journal": "Front. Physiol.", "date": "2022", "authors": "Kamoshita Maki, Kumar Rechal, Anteghini Marco, Kunze Markus, Islinger Markus, Martins Dos Santos V\u00edtor, Schrader Michael", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1N0S4", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N0S4" } ], "reference": [ { "type": "PubMed", "id": "35295584", "url": "https://glygen.org/publication/PubMed/35295584" } ] }, { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0A8M9P5U3", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M9P5U3" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:436918", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:436918", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GEJ2-1", "protein_name": "Chromodomain Y-like protein 2", "gene_name": "Cdyl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGDLYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHLPKDKKVKSGKQAGASKLLRDARSLPVERLSHRPLEPGKSKSTSHKRKRVNSPLSRSKKGSSGKAPDRATKTVSYRTTPSGLQIMPLKKAQNGLENGDAGSEKDESHFGNGSHQPDLELNDQLGEQETSDCDGTHSALVENGIGSALTNGGLNLHSPVKRKLETEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDDSKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPALGLGASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVSQVFWPTTFSQEVMLRVKEMASCSAVVLEDSKCLVRSFLKSVLEDVNEKECLMLKQLWSSSKGLDSLFSYLQDKIYEV", "length": 503 }, "evidence": [ { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" }, { "id": "SGD:S000004274", "url": "https://alliancegenome.org/gene/SGD:S000004274#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75521-1", "protein_name": "Enoyl-CoA delta isomerase 2", "gene_name": "ECI2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMAYLAWRLARRSCPSSLQVTSFPVVQLHMNRTAMRASQKDFENSMNQVKLLKKDPGNEVKLKLYALYKQATEGPCNMPKPGVFDLINKAKWDAWNALGSLPKEAARQNYVDLVSSLSPSLESSSQVEPGTDRKSTGFETLVVTSEDGITKIMFNRPKKKNAINTEMYHEIMRALKAASKDDSIITVLTGNGDYYSSGNDLTNFTDIPPGGVEEKAKNNAVLLREFVGCFIDFPKPLIAVVNGPAVGISVTLLGLFDAVYASDRATFHTPFSHLGQSPEGCSSYTFPKIMSPAKATEMLIFGKKLTAGEACAQGLVTEVFPDSTFQKEVWTRLKAFAKLPPNALRISKEVIRKREREKLHAVNAEECNVLQGRWLSDECTNAVVNFLSRKSKL", "length": 394 }, "evidence": [ { "id": "MGI:1916373", "url": "https://alliancegenome.org/gene/MGI:1916373#orthology", "database": "AGR" }, { "id": "MGI:1346064", "url": "https://alliancegenome.org/gene/MGI:1346064#orthology", "database": "AGR" }, { "id": "HGNC:14601", "url": "https://alliancegenome.org/gene/HGNC:14601#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-392", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-392#orthology", "database": "AGR" }, { "id": "FB:FBgn0035169", "url": "https://alliancegenome.org/gene/FB:FBgn0035169#orthology", "database": "AGR" }, { "id": "RGD:1359427", "url": "https://alliancegenome.org/gene/RGD:1359427#orthology", "database": "AGR" }, { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" }, { "id": "SGD:S000004274", "url": "https://alliancegenome.org/gene/SGD:S000004274#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q05871-1", "protein_name": "3,2-trans-enoyl-CoA isomerase", "gene_name": "ECI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSQEIRQNEKISYRIEGPFFIIHLMNPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFNMPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVEVNESLKYWVDGEPLKRFRQLGSKQRKHRL", "length": 280 }, "evidence": [ { "id": "MGI:1916373", "url": "https://alliancegenome.org/gene/MGI:1916373#orthology", "database": "AGR" }, { "id": "MGI:1346064", "url": "https://alliancegenome.org/gene/MGI:1346064#orthology", "database": "AGR" }, { "id": "HGNC:14601", "url": "https://alliancegenome.org/gene/HGNC:14601#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-392", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-392#orthology", "database": "AGR" }, { "id": "FB:FBgn0035169", "url": "https://alliancegenome.org/gene/FB:FBgn0035169#orthology", "database": "AGR" }, { "id": "RGD:1359427", "url": "https://alliancegenome.org/gene/RGD:1359427#orthology", "database": "AGR" }, { "id": "SGD:S000004274", "url": "https://alliancegenome.org/gene/SGD:S000004274#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q08558-1", "protein_name": "Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase", "gene_name": "DCI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSRVCYHINGPFFIIKLIDPKHLNSLTFEDFVYIALLLHKANDIDSVLFTVLQSSGKYFSSGGKFSAVNKLNDGDVTSEVEKVSKLVSAISSPNIFVANAFAIHKKVLVCCLNGPAIGLSASLVALCDIVYSQNDSVFLLFPFSNLGFVAEVGTSVTLTQKLGINSANEHMIFSTPVLFKELIGTIITKNYQLTNTETFNEKVLQDIKQNLEGLYPKSVLGMKELLHSEMKQKLIKAQAMETNGTLPFWASGEPFKRFKQLQEGNRRHKL", "length": 271 }, "evidence": [ { "id": "MGI:1916373", "url": "https://alliancegenome.org/gene/MGI:1916373#orthology", "database": "AGR" }, { "id": "MGI:1346064", "url": "https://alliancegenome.org/gene/MGI:1346064#orthology", "database": "AGR" }, { "id": "HGNC:14601", "url": "https://alliancegenome.org/gene/HGNC:14601#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-392", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-392#orthology", "database": "AGR" }, { "id": "FB:FBgn0035169", "url": "https://alliancegenome.org/gene/FB:FBgn0035169#orthology", "database": "AGR" }, { "id": "RGD:1359427", "url": "https://alliancegenome.org/gene/RGD:1359427#orthology", "database": "AGR" }, { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5XIC0-1", "protein_name": "Enoyl-CoA delta isomerase 2", "gene_name": "Eci2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAVTWSRARCWCPSLLQVLRLPVTKLHLGRPAMRATQQDFENAMNQVKLLKKDPGNEVKLRLYALYKQATEGPCTMPKPGVFDFVNKAKWDAWNALGSLPKETARQNYVDLVSSLSSSSEASSQGKGGADGKAQESKGILVTSEGGITKITFNRPSKKNAITFQMYQDIILALKNASTDDTVITVFTGAGDYYSSGNDLTNFTSASGGMEEAANKGAIVLREFVNTFIDFPKPLVAVVNGPAVGISVTLLGLFDAVYASDRATFHTPFSHLGQSPEACSSYTFPKMMGSAKAAEMLLFGKKLTAREAWAQGLVTEVFPESTFETEVWTRLKTYAKLPPNSMRISKELIRKNEKEKLHAVNEEECTTLRARWLSEECINAIMSFVTRKPKL", "length": 391 }, "evidence": [ { "id": "MGI:1916373", "url": "https://alliancegenome.org/gene/MGI:1916373#orthology", "database": "AGR" }, { "id": "MGI:1346064", "url": "https://alliancegenome.org/gene/MGI:1346064#orthology", "database": "AGR" }, { "id": "HGNC:14601", "url": "https://alliancegenome.org/gene/HGNC:14601#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-392", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-392#orthology", "database": "AGR" }, { "id": "FB:FBgn0035169", "url": "https://alliancegenome.org/gene/FB:FBgn0035169#orthology", "database": "AGR" }, { "id": "RGD:1359427", "url": "https://alliancegenome.org/gene/RGD:1359427#orthology", "database": "AGR" }, { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" }, { "id": "SGD:S000004274", "url": "https://alliancegenome.org/gene/SGD:S000004274#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AYK9-1", "protein_name": "Chromodomain Y-like protein", "gene_name": "Cdyl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLGSSQPSTKEAEPCTLQEKEEHPVDDTRQQNNAVPATVSDPDQVSPAVQDAETQVESIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHNERQKEGTLARANRASPSNARKQISRSTHSALSKTNPKALVVGKDHESKTNQLLATSQKFRKNTAPSLANRKNMDLAKSGIKILVPKSPIKGRTSIDGFHGESPEKLDQGAEDTVTPEVTAEKPTGALLGPGAERARMGSRPRIHSLVPQVSGPVTAAMATTLAVNGKGTSPFMDALTANGTVTIQTSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPIVLEESKALVRCNMKMELEQANERECDALKKIWGSAQGMDSMLKYLQRKIDEF", "length": 589 }, "evidence": [ { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" }, { "id": "SGD:S000004274", "url": "https://alliancegenome.org/gene/SGD:S000004274#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q78JN3-1", "protein_name": "Enoyl-CoA delta isomerase 3, peroxisomal", "gene_name": "Eci3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKPGVFNFVNKATWDARNALGSLPKETARKNYVDLVSSLSSSSEAPSQGKRGADEKARESKDILVTSEDGITKITFNRPTKKNAISFQMYLDIMHALKNASTDNSVITVFTGTGDYYSSGNDLKNLINDAGEIQDVVATSTKILREFVNCFIDFPKPLVAVVNGPAVGIAVTILALFDAVFASDRATFHTPFSQLSQIPEACSTYMFPKIMGPTKAAEMLLFGKKLTAREAWAQGLVTEVFPESTFETEVWTRLKTYSKLSPNVMRISKELIRKHEKQKLYTVNAEECAAALERMPREEYAKALRNFLFRKAKAKL", "length": 317 }, "evidence": [ { "id": "MGI:1916373", "url": "https://alliancegenome.org/gene/MGI:1916373#orthology", "database": "AGR" }, { "id": "HGNC:14601", "url": "https://alliancegenome.org/gene/HGNC:14601#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-392", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-392#orthology", "database": "AGR" }, { "id": "FB:FBgn0035169", "url": "https://alliancegenome.org/gene/FB:FBgn0035169#orthology", "database": "AGR" }, { "id": "RGD:1359427", "url": "https://alliancegenome.org/gene/RGD:1359427#orthology", "database": "AGR" }, { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" }, { "id": "SGD:S000004274", "url": "https://alliancegenome.org/gene/SGD:S000004274#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N8U2-1", "protein_name": "Chromodomain Y-like protein 2", "gene_name": "CDYL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASGDLYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHMSKDKRIKSGKQSSTSKLLRDSRGPSVEKLSHRPSDPGKSKGTSHKRKRINPPLAKPKKGYSGKPSSGGDRATKTVSYRTTPSGLQIMPLKKSQNGMENGDAGSEKDERHFGNGSHQPGLDLNDHVGEQDMGECDVNHATLAENGLGSALTNGGLNLHSPVKRKLEAEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDDSKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPALGLGASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVSQVFWPTTFSQEVMLRVKEMASCSAVVLEESKCLVRSFLKSVLEDVNEKECLMLKQLWSSSKGLDSLFSYLQDKIYEV", "length": 506 }, "evidence": [ { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D5D8-1", "protein_name": "Chromodomain Y-like protein 2", "gene_name": "Cdyl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGDLYEVERIVDKRKNKKGKWEYLIRWKGYGSTEDTWEPEHHLLHCEEFIDEFNGLHLSKDKRVKSGKQAGASKLLRDARGLPVERLSHRPLEPGKSKPSSHKRKRVNSPLSRPKKGSSGKAPDRATKTVSYRTTPSGLQIMPLKKAQNGLENGDAGSEKDESHFGNGSHQPDLELNDQLGEQEASDCDGTHSALVENGVGSALTNGGLNLHSPVKRKLETEKDYVFDKRLRYSVRQNESNCRFRDIVVRKEEGFTHILLSSQTSDNNALTPEIMKEVRRALCNAATDDSKLLLLSAVGSVFCSGLDYSYLIGRLSSDRRKESTRIAEAIRDFVKAFIQFKKPIVVAINGPALGLGASILPLCDIVWASEKAWFQTPYATIRLTPAGCSSYTFPQILGVALANEMLFCGRKLTAQEACSRGLVSQVFWPTTFSQEVMLRVKEMASCSAVVLEESKCLVRSFLKSVLEEVNEKECVMLKQLWSSSKGLDSLFSYLQDKIYEV", "length": 503 }, "evidence": [ { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" }, { "id": "SGD:S000004274", "url": "https://alliancegenome.org/gene/SGD:S000004274#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W0M0-1", "protein_name": "5.3.3.8", "gene_name": "Dci", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTYQGYKELLVEQQGKLLVAKFNNPKKKNCINRVAYQEMTRVLTEVNDDEGVTIVVFTGVGDIFTSGNDLSQSSNTDDIDAFFKQSNATFKAMVLSFVNCRKIVLALVNGPAIGIGATIVGLCDVAWCSETTYFYTPFTKLGLVPEGGSSYMLPLILGRSKASEILLLSEPLSAQEAYQFNFVSRIFKASELESVIWPKLRQYSELPTNSLLQGKRLVKDGFLENLIKANEAECKQLLQQFQHPEFAQAIIDFASRKNKAKL", "length": 262 }, "evidence": [ { "id": "MGI:1916373", "url": "https://alliancegenome.org/gene/MGI:1916373#orthology", "database": "AGR" }, { "id": "MGI:1346064", "url": "https://alliancegenome.org/gene/MGI:1346064#orthology", "database": "AGR" }, { "id": "HGNC:14601", "url": "https://alliancegenome.org/gene/HGNC:14601#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-392", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-392#orthology", "database": "AGR" }, { "id": "FB:FBgn0035169", "url": "https://alliancegenome.org/gene/FB:FBgn0035169#orthology", "database": "AGR" }, { "id": "RGD:1359427", "url": "https://alliancegenome.org/gene/RGD:1359427#orthology", "database": "AGR" }, { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" }, { "id": "SGD:S000004274", "url": "https://alliancegenome.org/gene/SGD:S000004274#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WTK2-1", "protein_name": "Chromodomain Y-like protein", "gene_name": "Cdyl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGIGNSQPNSQEAQLCTLPEKAEQPTDDNTCQQNNVVPATVSEPDQASPAIQDAETQVESIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHNERQKEGSLARASRASPSNARKQISRSTHSTLSKTNSKALVVGKDHESKSSQLLAASQKFRKNPAPSLANRKNMDLAKSGIKILVPKSPVKGRTSVDGFQGESPEKLDPVDQGAEDTVAPEVTAEKPTGALLGPGAERARMGSRPRIHPLVPQVSGPVTAAMATGLAVNGKGTSPFMDALAANGTVTIQTSVTGVTAGKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMKEVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMADAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLFSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRKIDEF", "length": 593 }, "evidence": [ { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" }, { "id": "SGD:S000004274", "url": "https://alliancegenome.org/gene/SGD:S000004274#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9WUR2-1", "protein_name": "Enoyl-CoA delta isomerase 2", "gene_name": "Eci2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVTWSRARCWCPSVLQVFRLQVAKLHLGRPTMRASQQDFENALNQVKLLKKDPGNEVKLRLYALYKQATEGPCNMPKPGMLDFVNKAKWDAWNALGSLPKETARQNYVDLVSSLSSSSEAPSQGKRGADEKARESKDILVTSEDGITKITFNRPTKKNAISFQMYRDIILALKNASTDNTVMAVFTGTGDYYCSGNDLTNFTSATGGIEEAASNGAVLLRDFVNSFIDFPKPLVAVVNGPAVGISVTLLGLFDAVFASDRATFHTPFSQLGQSPEACSSYTFPKMMGSAKAAEMLLFGKKLTAREAWAQGLVTEVFPESTFETEVWTRLKTYAKLPPNAMRISKELIRKNEKEKLYAVNAEECTTLQARWLSEECMNAIMSFVSRKPKL", "length": 391 }, "evidence": [ { "id": "MGI:1346064", "url": "https://alliancegenome.org/gene/MGI:1346064#orthology", "database": "AGR" }, { "id": "HGNC:14601", "url": "https://alliancegenome.org/gene/HGNC:14601#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-392", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-392#orthology", "database": "AGR" }, { "id": "FB:FBgn0035169", "url": "https://alliancegenome.org/gene/FB:FBgn0035169#orthology", "database": "AGR" }, { "id": "RGD:1359427", "url": "https://alliancegenome.org/gene/RGD:1359427#orthology", "database": "AGR" }, { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" }, { "id": "SGD:S000004274", "url": "https://alliancegenome.org/gene/SGD:S000004274#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y232-1", "protein_name": "Chromodomain Y-like protein", "gene_name": "CDYL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTFQASHRSAWGKSRKKNWQYEGPTQKLFLKRNNVSAPDGPSDPSISVSSEQSGAQQPPALQVERIVDKRKNKKGKTEYLVRWKGYDSEDDTWEPEQHLVNCEEYIHDFNRRHTEKQKESTLTRTNRTSPNNARKQISRSTNSNFSKTSPKALVIGKDHESKNSQLFAASQKFRKNTAPSLSSRKNMDLAKSGIKILVPKSPVKSRTAVDGFQSESPEKLDPVEQGQEDTVAPEVAAEKPVGALLGPGAERARMGSRPRIHPLVPQVPGPVTAAMATGLAVNGKGTSPFMDALTANGTTNIQTSVTGVTASKRKFIDDRRDQPFDKRLRFSVRQTESAYRYRDIVVRKQDGFTHILLSTKSSENNSLNPEVMREVQSALSTAAADDSKLVLLSAVGSVFCCGLDFIYFIRRLTDDRKRESTKMAEAIRNFVNTFIQFKKPIIVAVNGPAIGLGASILPLCDVVWANEKAWFQTPYTTFGQSPDGCSTVMFPKIMGGASANEMLLSGRKLTAQEACGKGLVSQVFWPGTFTQEVMVRIKELASCNPVVLEESKALVRCNMKMELEQANERECEVLKKIWGSAQGMDSMLKYLQRKIDEF", "length": 598 }, "evidence": [ { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6F7-1", "protein_name": "Testis-specific chromodomain protein Y 2", "gene_name": "CDY2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASQEFEVEAIVDKRQDKNGNTQYLVRWKGYDKQDDTWEPEQHLMNCEKCVHDFNRRQTEKQKKLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKHHRSKNCKLFAASKNVRRKAASTLSDTKNMEIINSTIETLAPDSPFDHKKTVSGFQKLEKLDPIAADQQDTVVFKVTEGKLLRDPLSHPGAEQTGIQNKTQMHPLMSQMSGSVTASMATGSATRKGIVVLIDPLAANGTTDMHTSVPRVKGGQRNITDDSRGQPFIKKMHFTIRLTESAITYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEMVNALNSAAADDSKLVLFSAAGSVFCCGLDFGYFVRHLRNDRNTASLEMVDTIKNFVNTFIQFKKPIVVSVNGPAIGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKLTAREACAKGLVSQVFLTGTFTQEVMIQIKELASYNAIVLEECKALVRCNIKLELEQANERECEVLRKIWSSAQGIESMLKYVENKIDEF", "length": 541 }, "evidence": [ { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Y6F8-1", "protein_name": "Testis-specific chromodomain protein Y 1", "gene_name": "CDY1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASQEFEVEAIVDKRQDKNGNTQYLVRWKGYDKQDDTWEPEQHLMNCEKCVHDFNRRQTEKQKKLTWTTTSRIFSNNARRRTSRSTKANYSKNSPKTPVTDKHHRSKNRKLFAASKNVRRKAASILSDTKNMEIINSTIETLAPDSPFDHKTVSGFQKLEKLDPIAADQQDTVVFKVTEGKLLRDPLSRPGAEQTGIQNKTQIHPLMSQMSGSVTASMATGSATRKGIVVLIDPLAANGTTDMHTSVPRVKGGQRNITDDSRDQPFIKKMHFTIRLTESASTYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAADDSKLVLFSAAGSVFCCGLDFGYFVKHLRNNRNTASLEMVDTIKNFVNTFIQFKKPIVVSVNGPAIGLGASILPLCDLVWANEKAWFQTPYTTFGQSPDGCSSITFPKMMGKASANEMLIAGRKLTAREACAKGLVSQVFLTGTFTQEVMIQIKELASYNPIVLEECKALVRCNIKLELEQANERECEVLRKIWSSAQGIESMLKYVENKIDEF", "length": 540 }, "evidence": [ { "id": "SGD:S000005706", "url": "https://alliancegenome.org/gene/SGD:S000005706#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ], "pmid": "" }, { "name": "peroxisomal matrix", "id": "GO:0005782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005782", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "fatty acid beta-oxidation", "id": "GO:0006635", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006635", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "fatty-acyl-CoA binding", "id": "GO:0000062", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000062", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ], "pmid": "" }, { "name": "delta(3)-delta(2)-enoyl-CoA isomerase activity", "id": "GO:0004165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004165", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ], "pmid": "" }, { "name": "isomerase activity", "id": "GO:0016853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016853", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5U3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P5U3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5U3" }, { "id": "PS51228", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ACB", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 89, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "5.3.3.8", "ec_name": "a (3Z)-enoyl-CoA = a 4-saturated (2E)-enoyl-CoA.", "evidence": [ { "id": "5.3.3.8", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:5.3.3.8" }, { "id": "5.3.3.8", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=5.3.3.8" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 167, "end_pos": 169 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9P256-1", "uniprot_ac": "A0A8M9P256", "uniprot_id": "A0A8M9P256_DANRE", "mass": { "chemical_mass": 146932.0, "monoisotopic_mass": 146932.0 }, "refseq": { "ac": "XP_021323902", "name": "DENN domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323902" }, "gene_names": [ { "name": "dennd3a", "type": "recommended", "evidence": [ { "id": "A0A8M9P256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256" } ] }, { "name": "dennd3a", "type": "synonym", "evidence": [ { "id": "XP_021323902", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323902" } ] } ], "protein_names": [ { "name": "DENN domain-containing protein 3", "type": "recommended", "evidence": [ { "id": "A0A8M9P256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256/entry#names_and_taxonomy" } ] }, { "name": "DENN domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323902", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323902" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323902" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P256", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dennd3a", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091230-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091230-6", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "797970", "url": "https://www.ncbi.nlm.nih.gov/gene/797970", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001194", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001194", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051696", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051696", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:797970", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797970", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CSRDSIM", "url": "https://omabrowser.org/oma/group/CSRDSIM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P256", "url": "https://www.orthodb.org/?gene=A0A8M9P256", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12296", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12296", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12296:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12296:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02141", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02141", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03455", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03455", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25570", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25570", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323902", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M1Q1P5", "url": "https://www.uniprot.org/uniprotkb/A0A8M1Q1P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1Q1P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1Q1P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P256", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P256-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091230-6", "url": "https://zfin.org/ZDB-GENE-091230-6", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MADNVPCGLLEACVLLGVSNERLKELCPGKDADVLVEAEVLQVHAPPFITKDRSCNGGVDQGVAPAFSRVQKRRSFKKKKRERPVSTLSNSSQASESEELSVPQNIDLIALPQLCFPDGLRITNESREDSYHFLVFTDVFGNQTHGVVAQYCRPVQFQQDNVIYANGHRTNEHKRLYTTFSICVISKYPYYNALRDCLSCFLFQMKTSRVSDFDEQVKEFSAKLALVPIPPSGPLHVVFNLRPLQIELPSRLDVDRPVMDLDLHLPFLCFKPKQILQIISSILMEQRVVFLSTDWAKLTLVSECFMIFIHPLRWQHPFVPVLSRQMLDFIMAPTAYLMGCHTYHFQEVAEEIEDLVLIDIDQGTVSSSTSDRFDLPDVPLAARDCFIFRCGGLQLHYDLDVCGSSSQTDVNDLRAHRRLWQRKLNSSILNISMELIVNIFSEVCDFLNYEHRVFNSEEFLRSRDSTDSAFYRKVLDTHIFHSFLRERLNRKNDAFTRMQLNIRSETRRLKIMTESPRRPTMEEINRKHRAENGLNKRLGMSMPNLADSRSLTVPIRQMSMMSVRMPLQMGSWSPIKPVKTFKLPEFPPPLAYHYVQNYYHDLIGQLDRSISSASPDDSALLARYYYLRGLVNSVTGRHVDALADFQSLYKTDMEIFPAQLLNTLVEALPVEEKRIAERRTDLKRLMSRVRRENEKDRARLVDGGTVKRFELPKKHLQKEDFVRRVQESGIVKDLETIKRLFEALTLGVEDSCRSVFYLELDGQVKQVDPETFRFFYNFWKETEAAAQDVDLPAVVLEHLENDECVYKVSSSVKTSHGVGKIAMTQRRLFLLTEGRPGYVEITKFRDIEDVRISSAPFLLLRIPSLKIRTSLRRESFEANLKSECDLWHLMIKEMWAGRKMADQHKDPQFMEQALTNALLMDAVVGSLQSQKAIYAATKLAYFDKMKSEVPMMVPKTTSDTLKHKINPSLDQTSPQAVDVLLYTPGQLGVSDVDGGGNPKLWCALSDGKLLVFDAASWSMQHNSVQVGTSRLTCMLAVNEQQLWIGSKDSFIYIINPRSVSCNKQLTEHRCELTGLALEERADKFSQTVAYSCSEDCNVIVWDVSSLQVRRQFRVSCGRLQSMHVHNGMLWCCGRDCVLEVRRNGSVHRRISLPDHLLSSPKGFSSFLLFNESEQLWAGFADAGELCVWHCRDISKPFIRIQLKDCAAVTCMIRVKNQIWVGGYNGSVTDRRVRGKIYIVNTDRYTVEKELQAHADAVQTMCSAEDRYVLSGAAQDDGKIGIWKVE", "length": 1285, "header": "tr|A0A8M9P256-1|A0A8M9P256_DANRE Isoform 1 of DENN domain-containing protein 3 OS=Danio rerio OX=7955 GN=dennd3a PE=4 SV=1 CANONICAL=A0A8M9P256-1" }, "isoforms": [ { "isoform_ac": "A0A8M1Q1P5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256/entry#A0A8M1Q1P5-1", "sequence": { "sequence": "MADNVPCGLLEACVLLGVSNERLKELCPGKDADVLVEAEVLQVHAPPFITKDRSCNGGVDQGVAPAFSRVQKRRSFKKKKRERPVSTLSNSSQASESEELSVPQNIDLIALPQLCFPDGLRITNESREDSYHFLVFTDVFGNQTHGVVAQYCRPVQFQQDNVIYANGHRTNEHKRLYTTFSICVISKYPYYNALRDCLSCFLFQMKTSRVSDFDEQVKEFSAKLALVPIPPSGPLHVVFNLRPLQIELPSRLDVDRPVMDLDLHLPFLCFKPKQILQIISSILMEQRVVFLSTDWAKLTLVSECFMIFIHPLRWQHPFVPVLSRQMLDFIMAPTAYLMGCHTYHFQEVAEEIEDLVLIDIDQGTVSSSTSDRFDLPDVPLAARDCFIFRCGGLQLHYDLDVCGSSSQTDVNDLRAHRRLWQRKLNSSILNISMELIVNIFSEVCDFLNYEHRVFNSEEFLRSRDSTDSAFYRKVLDTHIFHSFLRERLNRKNDAFTRMQLNIRSETRRLKIMTESPRRPTMEEINRKHRAENGLNKRLGMSMPNLADSRSLTVPIRQMSMMSVRMPLQMGSWSPIKPVKTFKLPEFPPPLAYHYVQNYYHDLIGQLDRSISSASPDDSALLARYYYLRGLVNSVTGRHVDALADFQSLYKTDMEIFPAQLLNTLVEALPVEEKRIAERRTDLKRLMSRVRRENEKDRARLVDGGTVKRFELPKKHLQKEDFVRRVQESGIVKDLETIKRLFEALTLGQVKQVDPETFRFFYNFWKETEAAAQDVDLPAVVLEHLENDECVYKVSSSVKTSHGVGKIAMTQRRLFLLTEGRPGYVEITKFRDIEDVRISSAPFLLLRIPSLKIRTSLRRESFEANLKSECDLWHLMIKEMWAGRKMADQHKDPQFMEQALTNALLMDAVVGSLQSQKAIYAATKLAYFDKMKSEVPMMVPKTTSDTLKHKINPSLDQTSPQAVDVLLYTPGQLGVSDVDGGGNPKLWCALSDGKLLVFDAASWSMQHNSVQVGTSRLTCMLAVNEQQLWIGSKDSFIYIINPRSVSCNKQLTEHRCELTGLALEERADKFSQTVAYSCSEDCNVIVWDVSSLQVRRQFRVSCGRLQSMHVHNGMLWCCGRDCVLEVRRNGSVHRRISLPDHLLSSPKGFSSFLLFNESEQLWAGFADAGELCVWHCRDISKPFIRIQLKDCAAVTCMIRVKNQIWVGGYNGSVTDRRVRGKIYIVNTDRYTVEKELQAHADAVQTMCSAEDRYVLSGAAQDDGKIGIWKVE", "length": 1270, "header": "tr|A0A8M1Q1P5-1|A0A8M9P256_DANRE Computationally mapped isoform of DENN domain-containing protein 3 OS=Danio rerio OX=7955 GN=dennd3a PE=4 SV=1 CANONICAL=A0A8M9P256-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P256-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256/entry#A0A8M9P256-1", "sequence": { "sequence": "MADNVPCGLLEACVLLGVSNERLKELCPGKDADVLVEAEVLQVHAPPFITKDRSCNGGVDQGVAPAFSRVQKRRSFKKKKRERPVSTLSNSSQASESEELSVPQNIDLIALPQLCFPDGLRITNESREDSYHFLVFTDVFGNQTHGVVAQYCRPVQFQQDNVIYANGHRTNEHKRLYTTFSICVISKYPYYNALRDCLSCFLFQMKTSRVSDFDEQVKEFSAKLALVPIPPSGPLHVVFNLRPLQIELPSRLDVDRPVMDLDLHLPFLCFKPKQILQIISSILMEQRVVFLSTDWAKLTLVSECFMIFIHPLRWQHPFVPVLSRQMLDFIMAPTAYLMGCHTYHFQEVAEEIEDLVLIDIDQGTVSSSTSDRFDLPDVPLAARDCFIFRCGGLQLHYDLDVCGSSSQTDVNDLRAHRRLWQRKLNSSILNISMELIVNIFSEVCDFLNYEHRVFNSEEFLRSRDSTDSAFYRKVLDTHIFHSFLRERLNRKNDAFTRMQLNIRSETRRLKIMTESPRRPTMEEINRKHRAENGLNKRLGMSMPNLADSRSLTVPIRQMSMMSVRMPLQMGSWSPIKPVKTFKLPEFPPPLAYHYVQNYYHDLIGQLDRSISSASPDDSALLARYYYLRGLVNSVTGRHVDALADFQSLYKTDMEIFPAQLLNTLVEALPVEEKRIAERRTDLKRLMSRVRRENEKDRARLVDGGTVKRFELPKKHLQKEDFVRRVQESGIVKDLETIKRLFEALTLGVEDSCRSVFYLELDGQVKQVDPETFRFFYNFWKETEAAAQDVDLPAVVLEHLENDECVYKVSSSVKTSHGVGKIAMTQRRLFLLTEGRPGYVEITKFRDIEDVRISSAPFLLLRIPSLKIRTSLRRESFEANLKSECDLWHLMIKEMWAGRKMADQHKDPQFMEQALTNALLMDAVVGSLQSQKAIYAATKLAYFDKMKSEVPMMVPKTTSDTLKHKINPSLDQTSPQAVDVLLYTPGQLGVSDVDGGGNPKLWCALSDGKLLVFDAASWSMQHNSVQVGTSRLTCMLAVNEQQLWIGSKDSFIYIINPRSVSCNKQLTEHRCELTGLALEERADKFSQTVAYSCSEDCNVIVWDVSSLQVRRQFRVSCGRLQSMHVHNGMLWCCGRDCVLEVRRNGSVHRRISLPDHLLSSPKGFSSFLLFNESEQLWAGFADAGELCVWHCRDISKPFIRIQLKDCAAVTCMIRVKNQIWVGGYNGSVTDRRVRGKIYIVNTDRYTVEKELQAHADAVQTMCSAEDRYVLSGAAQDDGKIGIWKVE", "length": 1285, "header": "tr|A0A8M9P256-1|A0A8M9P256_DANRE Isoform 1 of DENN domain-containing protein 3 OS=Danio rerio OX=7955 GN=dennd3a PE=4 SV=1 CANONICAL=A0A8M9P256-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:797970", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797970", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5NUL1-1", "protein_name": "DENN domain-containing protein 3", "gene_name": "DENND3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEDALPSGLLEVCLLVGVPREQLRTQLQDAQRKPRSLLPLDPEVLSVFVPPLISRDDIHSTNTSGSNFNRGKRRSFRKKKERPKLENAKTVNGEQKAPGTEDITVPKDIDLIGLPQLCFPGGLFITSEPREDHIHFLVFTDVCGNRTYGVVAQYYQPMQDGCIASNGQTQWESVRAGKKPGCFVPLAICVISRYPYFNALKDCLSCLLVQLRSVKDLDIDDHIKEFAAKLFLIPSPPPGPLHLVFNMKPLQIIIPSREDPDSPVIDLDLHLPLLCFKPEQVLQIMTCILTERKMVFFSSDWALLTLVAECFMLYLHPLQWQHTFVPLLSRHMLDFVMAPTSFLMGCHADHFEEVSTEGEDLILINIDDGNISHSKMVEEEPEIPDVPAQAAETFKKRVESLQLHYDLELCHLRATTDLGELQMRRRAWQQKLNTEVQQMTLQLIVNIFREVKDHLNYEHRVFNSEEFLKTRATGDQPFYGKVLETYMFHSFLKARLNRKMDAFARLELSTQSEEDRFNLMFRAPRRLTMEKMASKRFNSQNIINRRMVISMPNLQDIKLPESPTRKSSLRRIETSIAMKKPSKSVSTFKIPEIHFPLMSHCVHSYYTEFFNHLSKAINTLAPDNSALLARYFYLRGLISLMQGKLLNALSDFQNLDKTDLRIFPTELVRKIVETLPPSERFQADRKPELKRLISLVMEQQREVTKIDDHVKHFELPKTHMQLHDFVKRIQESGIVRDTDTIHRLFDALTVGQQKQIDPETFRDFYNYWKETEAEAQEVNLPPAVIEHLDKNECVYKLSCSVKTNYGVGKIALTQKRLFLLTEGGRPGYVHIAAFREIEDVKNTTVAFLLLRIPTLRIETIYKKQVFEANLKTECDLWYLIVKEMWAGKKMADDHKDPQYIQQALTNVLLMDAVVGALQSSKAIYAASKLSYFDRMKNEVPMMIPKTTSETLKHKINPSAGETFPQAIDVLLYTPGHLDISERPDNAHPKLWCALNEGKVVVFDASTWTIQQHCFRMGRCKLTCMVMVEQSQVWIGSQDSIIYIINTHSMSCNKQLNDHRSGITDIVVEKRNGIPSEAYSSSLDGTVIAWNINTLKVNRAFQLPCQNLTSIKLHNDQLWCCTGSCIFVMSTYEFRLQMKIEHHLKDVCSYFLCFQLFPERNEVWASYSGSSDLYIWNTKDFASTPQKIHLQDCSEITCMIQVKNQMWVGSSGTSQGKIKGKIYVISAEKKTVEKELFGHADTVKALCSAEDRYVLSGAGKEEGKIAIWKVE", "length": 1270 }, "evidence": [ { "id": "A0A8M9P256", "url": "https://omabrowser.org/oma/group/A0A8M9P256/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A287AF91-1", "protein_name": "DENN domain-containing protein 3", "gene_name": "DENND3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEAAPQHLELPWGLLELCALLGPPRDSLRGPEQGAQKKGAKSPPSLAPEVLSVFVPPFVSKEDSAAAAAGASSGTLGKAKRRSFRRKRDRPRAEPGRGPRGAEPEDASIPDGVDLLALPQLCFPGGVRVASEPEEDRVHFLVLTDVCGNRTHGVVAQYYRPLHDKHCFYNGKTQWEASGPSGGAAGCFVPFAVCVVSRFPYYNALKDCLSCLLTHLKLCKDFEVDNHIKDFAAKLSLIPSPPPGPLHLVFNMKPLQIVFPSRADPESPLVDLDLHLPLLCFRPEKVLQILTCLLTERRLVFFSSSWALLTLVAECFMAFLHPLQWQHTFVPILSRQMLDFVMAPTSFLMGCHLDHFAEVSKEADGLILINIDTGSITSSNSEDADVPDIPLLAAQTFIQSIQSLQLHHELHLAHLCASTDLNEGRASRRAWQHRLNCQIQQISLQLLVSIFREVKNHLNYEHRVFNSEEFLKTRAPGDQQFYKQVLETYMFHAFLKARLSRRMDAFAQMELHTQSEEDRINGTLLSPRRPTIEKMASRKSTLLQAAPRRKVVSMPDLQVIAVPELLPRNSSLRKIHTADGGGSHAAVSLALQPTYTFKIPEVHFPLLAQCVQVFYEDCVAQLSKAMVSLAPENSVLLARYFYLRGLVQLMQGRLLGALLDFQSLYKTDVHIFPADLVQRTVESLSGPERTQAERMPELRRLISEVMDKPVDAPKADDRVKNFELPKTHLQLDDFVKRVQESGVVKDTGVIHRLFEALTVGQQKQIDPETFREFYNCWKEAEAEAQEVSLPLSALEHLDKNECVYKLSSSVKTSLGVGKIAMTQKRLFLLTEGRPGYVEIATFRDMEEVRSTTVAFLLLRIPTLKIKTASKKEVFEANLKTECDLWHLMVKEMWAGKKLADEHKDPQYVQQALTHVLLMDAVVGTLQSPGAIYAASKLSHFDKLRSEMPMVVPKTTSETLKHKINPSAGETAPRAVDVLLYTPGHLDPAEKVEDAHPKLWCALNGGKVVVFDASSWTIHQHCFKVGNSKLNCMVMVEQSQVWVGSEDSVIYIINVHSMSCHKQLTDHRASVTGLVVQDGAPSAVYSCSADGTVLAWNVSSLRVTSRFQVPGDGLSSITLYRDRLWCCAGNSIVVMTANGFLRQELKIDEGFKDRSAFLAFQLLHEQEQLWAACSRYDSIYVWSLEDLARPPQRVCLRDCSAITCMIRVKQQIWVGGTGLSQGRPKGKIYVIDAERRTVEKELVAHADTVKTLCSAEDRYVLSGSGCEEGKIAIWKVE", "length": 1277 }, "evidence": [ { "id": "A0A8M9P256", "url": "https://omabrowser.org/oma/group/A0A8M9P256/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M3ATM0-1", "protein_name": "DENN domain-containing protein 3", "gene_name": "dennd3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADGLPSGLLEACIVIGASSDKLNKLSQSLSQLNGSPLPLLDPEVLQVHRPLFCLKQNVTEPAVETLSPTQQWCSPIQKNNDKPTFNTVNPKEEATENASTLKELDLAALPQLCFPGGLQVTKKQKDEQFHYLVFTDVLGNQSHGVVLQFYRATQEGKQHQNGHQTSYKPPQLYTPYAVCVISKHPYYSALKDCLSSLLRELKICQMTEMEERAKEFSAKLSVVPVPPPGQLHVMFIMQPLMIVLPSREDQHHPVVDLDLHLPFLCFKSKEVLQIIACILTEQRMVFFSSDWAKLTLIAECFMLYIWPLRWQHPLVPILSQHMLDFVMAPTAFIMGCHISHYEEVAEENDDLILINIDEGTVSCSSILDFDIPDVPYAAAQCFKSRRKGLRLHYDLNLLNQSICGDLNELRNQRRCWQQRLNKEIQNISLELLFNMFRDVSDYLNYEHRVFNTDEFLKTRDPEDQSFYKKVLETPIFHSFLKERLNRKMDMFAQLELSNLTEEQKYRNAVDSSRRPTIQEMRRSSSKNGHRSSLFNQDDKQVSPTSTPEMPLNTTAWPVKIFQLPFFPRPLNHLNILHYIEDLILKLNKAISAVSPDDSSLLARYFYLRGLINMQNSKRLDALSDFQNLYKTDIGVFPRELVKTLVHSLQKEERVQVEERCELRRLICQVKSKEKREQMECDNHVKKFQLPKAPMQLEEFVKCIQESGIVRDVATIQRLFEALNAGGQKQIVPELFRMFYKFWKETEAEAQDVLLPAEVLERLDSNECVYKLSRSVKTSYGVGKIAMTQKRIFLLTTGSPGYVDITKFRDIEEVKISAPVRILRNSSLKIKNSLRDEIFEANLKSECELWNLMVKEMWAGRMMADNNKDPQYVQQALTNVLLMDAVVGCLQTQKSVCAASKLAYHEKLRQEVPVIIPRDTAWTLKHKINPSQNMMNPQSVDVLFYSPGQLTFPDSDVDVNPKLWCGLGCGKVVVFDAASWSLKQNCIHLGDSRLNCMMGLDQDQVWIGSEDSVIYIINTRSMLCHKQLTEHRGELTDFTLEKLSPESRSSRAQVYSCSADGTVIVWDVPSLKVKRQFHLSCDRLQSIQIHNGALWCGARDCIMMLKPNGDQLWKIHLPDKMKATANFFNRVTLFPERQQIWTSFTDFAELCIWDFNDPVKPPKRLKLPNCKGVTCMIKVKKQVWIGCGGGSGLSKVVGKILVLDSESLEVEKELEAHEDSVQVLFSVEDRYVLSGSAKLEGRIAIWRVD", "length": 1249 }, "evidence": [ { "id": "HGNC:29134", "url": "https://alliancegenome.org/gene/HGNC:29134#orthology", "database": "AGR" }, { "id": "MGI:2146009", "url": "https://alliancegenome.org/gene/MGI:2146009#orthology", "database": "AGR" }, { "id": "RGD:1311559", "url": "https://alliancegenome.org/gene/RGD:1311559#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A9J7FG86-1", "protein_name": "DENN domain-containing protein 3", "gene_name": "Dennd3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEPTARHLSLPSGLLELCALLGASQDSLRGLEQIGQKRGLKSVSSLAPEVLSVFVPPFTTQDDGQVSENSCMLSKTRRRSFRKKREKPRIEYWKSHPGDSKGPDSEDVTIPGGVDLLALPQLCFPGGVCVAPEPKEDYIHFLVLTDVCGNRTYGVVAQYYRPLHDEYCFYNGKTHWEPSVSSARRFVPFAVCVVSRFPYYNSLKDCLSCLLTHLKLCKDFEVDNHIKDFAARLSLIPCPPPGPLHLIFNMKPLQVVFPSRADPESPIIDLDLHLPLLCFRPEKVLQILTCILTEQRIVFFSSDWALLTLIAECFVVYLHPLQWQHTFVPILSGQMLDFVMAPTSFLMGCHLDHFEEVRKEADGLILIDIDHGSVTCSKSSDNDIDIPDVPLLLAQTFIQRVQSLQMHPDLHLAHLSSSTDLNEGLARRRAWQQTLNCKIQHISLQLLVGIFREVKNHLNYEHRVFNSEEFLKTRAAGDQQFYKQVLDTYMFHSFLKARLNGRMDAFARMDLDTQSEEDRIDRMLISPRRPTVEKMTSRKSSPLHVTHRRMVVSMPNLQDISLPELPPRNSSLRIMDTSSCKSSSSVFKVTPKSTYTFKIPEIHFPLMNQCVQAYYTDLITLLSKAMSLLGPGDSLLLARYFYLRGLIQVMQGQLLSALLDFQNLYKTDIGIFPADLVKSMVESMSASEWAQAERTPELRRLITEVLDKPGETPKADDAVKNFELPKKHMQLNDFVKRVQESGIVKDAVIIHRLFDALTVGHEKQIDPETFRDFYTCWKETEAEAQEVSLPALLTDHLDKNECVYKLSSSVKTNRGVGKIAMTQKRLFLLPEGRPGYVEIATFRNIEEVKNTTVAFLLLKIPTLKIKTVAKKEVFEANLKSECDLWHLMVKEMWAGKKLADDHKDPQYVQQALTNVLLMDAVVGTLQSPSAIYAASKLAYFDKMRSEMPMAVPKTTSETLKHKINPSAGETAPQAVDVLLYTPGRLDPAEKVEDAHPKLWCALNEGKVVVFDASSWTIHQHCFKVGASKVNCMVMAEHSQVWVGSEDSVIYIINVHSMSCNKQLTDHRAAVTGLVVQNGKKPSEVYSCSLDGTVLAWNVSTLRVTSRFQLPYGDLMSISLHNDCLWCCTGHSLVVVTMQGFHRHELKINSPYKASTSLLAFQLLPEKEQLWVACAGCSDLYIWSLKDLGQPPRKTHLQDCTEVSCMIRVKRQIWVGGRGLSQGKPRGKIFVMDVEKMTVEKELVAHSDTVKTLCSAEDRYVLSGAGHEEGKIAIWKVE", "length": 1278 }, "evidence": [ { "id": "A0A8M9P256", "url": "https://omabrowser.org/oma/group/A0A8M9P256/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A2RT67-1", "protein_name": "DENN domain-containing protein 3", "gene_name": "Dennd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEPAARHLSLPSGLLELCALLGASQDSLRGLEQIAQKRGVKSASSLVPEVLSVFVPPFTTKEDGQVPGASCALGKGRRRSFRKKREKPRMEPWKSHPGDSKGPDSEDVTIPGGVDLLALPQLCFPGCVCVASEPKEDYIHFLVLTDVCGNRTYGVVAQYYRPLHDEYCFYNGKSHWEPSVISARCFVPFAVCVVSRFPYYNSLKDCLSCLLTHLKLCKDFEVDNHIKDFAARLSLIPSPPPGPLHLIFNMKPLQVVFPSRADPESPIVDLDLHLPLLCFRPEKVLQILTCILTEQRIVFFSSDWALLTLMAECFVAYLHPLQWQHTFVPILSGQMLDFVMAPTSFLMGCHLDHFEEVRKEADGLVLIDIDHGSVTCSKSSDDNIDIPDVPLLLAQTFIQRVQSLQLHPDLHLAHLSASTDLNEGRARRRAWQQTLNCKIQHITLQLLVGIFREVKNHLNYEHRVFNSEEFLKTRAAGDQQFYKQVLDTYMFHSFLKARLNGRMDAFARMDLDTQSEEDRIDRMLISPRRPTVEKMASRKASPLHITHRRMVVSMPNLQDISLPELPPRNSSLRIMDTSNCRSSSPVLKVTPKSTYMFKIPDIHFPLESQCVQAYYTDFVTLLSKAMALLGPGDSLLLARYFYLRGLLHLMQGQLLSALLDFQNLYKTDIGIFPADLVKRTVESMSASERAQAERTPELRRLITEVFDKHGEAPKADDAVKNFELPKKHMQLNDFVKRVQESGIVKDAVIIHRLFDALTFGHEKQIDPETFRDFYTCWKETEAEAQEVSLPALLMEHLDKNECVYKLSSSVKTNRGVGKIAMTQKRLFLLTEGRPGYVEIATFRNIEEVKNSTVAFLLLRIPTLKIKTVAKKEVFEANLKSECDLWHLMVKEMWAGKQLADDHKDPQYVQQALTNVLLMDAVVGTLQSPSAIHAASKLAYFDNMKKKSPMAVPKTTSETLKHKINPSAGETAPQAIEVLLYTPGRLDPAEKVEDAHPKLWCALNEGKVVVFDASSWTVHQHCFKVGSSKVNCMVMAEHNQVWVGSEDSVIYIINVHSMSCNKQLTDHRSPVTGLAVHNGKKPSEIYSCSLDGTVIAWNVSTLRVISRFQLSYGDLLSISLHNDRIWCCTVHKILVVTPQGFVRQELKHPKDASFLAFQLLPEEQQLWAASTGVSELYMWSLKDLDQPPQKTYLQDCSEVTCMIRVKRQIWVGGRGLSQGKTRGKIYVMDVEKVTVEKELVAHLDTVRTLCSAEDRYVLSGAGQEEGKIAIWKVE", "length": 1274 }, "evidence": [ { "id": "HGNC:29134", "url": "https://alliancegenome.org/gene/HGNC:29134#orthology", "database": "AGR" }, { "id": "MGI:2146009", "url": "https://alliancegenome.org/gene/MGI:2146009#orthology", "database": "AGR" }, { "id": "RGD:1311559", "url": "https://alliancegenome.org/gene/RGD:1311559#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091230-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091230-6#orthology", "database": "AGR" }, { "id": "A0A8M9P256", "url": "https://omabrowser.org/oma/group/A0A8M9P256/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2RUS2-1", "protein_name": "DENN domain-containing protein 3", "gene_name": "DENND3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRSLRKKREKPRPEQWKGLPGPPRAPEPEDVAVPGGVDLLTLPQLCFPGGVCVATEPKEDCVHFLVLTDVCGNRTYGVVAQYYRPLHDEYCFYNGKTHRECPGCFVPFAVCVVSRFPYYNSLKDCLSCLLALLKPCKDFEVDSHIKDFAAKLSLIPSPPPGPLHLVFNMKSLQIVLPARADPESPILDLDLHLPLLCFRPEKVLQILTCILTEQRIVFFSSDWALLTLVTECFMAYLYPLQWQHPFVPILSDQMLDFVMAPTSFLMGCHLDHFEEVSKEADGLVLINIDHGSITYSKSTDDNVDIPDVPLLAAQTFIQRVQSLQLHHELHAAHLLSSTDLKEGRAHRRSWQQKLNCQIQQTTLQLLVSIFRDVKNHLNYEHRVFNSEEFLKTRAPGDHQFYKQVLDTYMFHSFLKARLNRRMDAFAQMDLDTQSEEDRINGMLLSPRRPTVEKRASRKSSHLHVTHRRMVVSMPNLQDIAMPELAPRNSSLRLTDTAGCRGSSAVLNVTPKSPYTFKIPEIHFPLESKCVQAYHAHFVSMLSEAMCFLAPDNSLLLARYLYLRGLVYLMQGQLLNALLDFQNLYKTDIRIFPTDLVKRTVESMSAPEWEGAEQAPELMRLISEILDKPHEASKLDDHVKKFKLPKKHMQLGDFMKRVQESGIVKDASIIHRLFEALTVGQEKQIDPETFKDFYNCWKETEAEAQEVSLPWLVMEHLDKNECVCKLSSSVKTNLGVGKIAMTQKRLFLLTEGRPGYLEISTFRNIEEVRRTTTTFLLRRIPTLKIRVASKKEVFEANLKTECDLWHLMVKEMWAGKKLADDHKDPHYVQQALTNVLLMDAVVGTLQSPGAIYAASKLSYFDKMSNEMPMTLPETTLETLKHKINPSAGEAFPQAVDVLLYTPGHLDPAEKVEDAHPKLWCALSEGKVTVFNASSWTIHQHSFKVGTAKVNCMVMADQNQVWVGSEDSVIYIINVHSMSCNKQLTAHCSSVTDLIVQDGQEAPSNVYSCSMDGMVLVWNVSTLQVTSRFQLPRGGLTSIRLHGGRLWCCTGNSIMVMKMNGSLHQELKIEENFKDTSTSFLAFQLLPEEEQLWAACAGRSEVYIWSLKDLAQPPQRVPLEDCSEINCMIRVKKQVWVGSRGLGQGTPKGKIYVIDAERKTVEKELVAHMDTVRTLCSAEDRYVLSGSGREEGKVAIWKGE", "length": 1198 }, "evidence": [ { "id": "HGNC:29134", "url": "https://alliancegenome.org/gene/HGNC:29134#orthology", "database": "AGR" }, { "id": "MGI:2146009", "url": "https://alliancegenome.org/gene/MGI:2146009#orthology", "database": "AGR" }, { "id": "RGD:1311559", "url": "https://alliancegenome.org/gene/RGD:1311559#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091230-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091230-6#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4A2H4-1", "protein_name": "DENN domain-containing protein 3", "gene_name": "Dennd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTPGFVRSHWKPRAGHPAAARHSACHLFCFSAFGPPGPRRARPAAPDPAASRAPAPRPPQPSGPGLTRSEAGARWGPCPPKPAPRPAPPNALSPRLRGLEQIAQKRGVNGASSLVPEVLSVFVPPFTTKEDGQVVGASCTLSKGRRRSFRKKREKPRMESWKSHPGDSKGPDSEDVTIPGGVDLLALPQLCFPGGVCVASEPKEDYIHFLVLTDVCGNRTYGVVAQYYRPLHDEYCFYNGKSHWEPSMSSARRFVPFAVCVVSRFPYYNSLKDCLSCLLTHLKLCKDFEVDNHIKDFAARLSLIPSPPPGPLHLIFNMKPLQVVFPSRADPESPIIDLDLHLPLLCFRPEKVLQILTCILTEQRMVFFSSDWALLTLMAECFVAYVHPLQWQHTFVPILSGQMLDFVMAPTSFLMGCHLDHFEEVRKEADGLVLIDIDLGSVTCSKSSDEDVDIPDVPLLLAQAFIQRVQSLQLHPDLHLAHLSASTDLNEGRARRRAWQQALNCKIQHITLQLLVGIFREVKNHLNYEHRVFNSEEFLKTRAAGDQQFYKQVLDTYMFHSFLKARLNGRMDAFARMDLDTQSEEDRIDRMLISPRRPTVEKMASRKASPLNIAHRRMVVSMPNLQDISLPELPPRNSSLRIMDTSSCKSSSPVLKVTPKSTYTFKIPEIHFPLVSQCVQAYFTDLVTLLSKAMALLGPGDSLLLARYFYLRGLIHLMQGQLLNALLDFQSLYKTDIRIFPADLVKGMVDSMSASERAQAERTPELRRLITEVFDKQGEAPKVDDAVKNFELPKKHMQLNDFVKRVQESGIVKDTTIIHRLFDALTVGHEKQIDPETFRDFYTCWKETEAEAQEVSLPALLVDHLDRNECVYKLSSSVKTNRGVGKIAMTQKRLFLLPEGRPSYVEIATFRNIEEVKSTTVAFLLLKIPTLKIKTVAKKEVFEANLKSECDLWHLMVKEMWAGKKLADDHKDPQYVQQALTNVLLMDAVVGTLQSSGAIYAASKLAYFDKMKNELPMAVPKTTSETLKHKINPSAGETAPQAIEVLLYTPGRLDPAEKVEDAHPKLWCALNEGKVVVFDASSWTIHQHCFKVGSSKVNCMVMAEHSQVWVGSEDSVIYIINVHSMSCNKQLTDHRSAVTGLAVPSGKKPSAVYSCSLDGTVLAWNVSTLRVISRFQLQHGDLMSISLHNDRVFCCTARSILVVTLQGFVRQELRIQPSEEPSASFLAIQLLPEEQQLWVACTGVSELYIWSLKDLGQPPQKTHLQDCTEVTCMIRVKRQIWVGGRGLSQGKTRGKIYVMDVEKVTLEKELVAHSDTVRTLCSAEDRYVLSGAGGEEGKIAIWKVE", "length": 1345 }, "evidence": [ { "id": "HGNC:29134", "url": "https://alliancegenome.org/gene/HGNC:29134#orthology", "database": "AGR" }, { "id": "MGI:2146009", "url": "https://alliancegenome.org/gene/MGI:2146009#orthology", "database": "AGR" }, { "id": "RGD:1311559", "url": "https://alliancegenome.org/gene/RGD:1311559#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091230-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091230-6#orthology", "database": "AGR" }, { "id": "A0A8M9P256", "url": "https://omabrowser.org/oma/group/A0A8M9P256/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "enteric nervous system development", "id": "GO:0048484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048484", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P256", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256" } ], "pmid": "" }, { "name": "regulation of Rab protein signal transduction", "id": "GO:0032483", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032483", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P256", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256" } ], "pmid": "" }, { "name": "endosome to lysosome transport", "id": "GO:0008333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008333", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P256", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P256", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256" } ], "pmid": "" }, { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P256", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P256", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1143, "end_pos": 1145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1170, "end_pos": 1172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1224, "end_pos": 1226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P256", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P256" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 494, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1143, "end_pos": 1145 }, { "start_pos": 1170, "end_pos": 1172 }, { "start_pos": 1224, "end_pos": 1226 }, { "start_pos": 124, "end_pos": 126 }, { "start_pos": 142, "end_pos": 144 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 430, "end_pos": 432 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P0S4-1", "uniprot_ac": "A0A8M9P0S4", "uniprot_id": "A0A8M9P0S4_DANRE", "mass": { "chemical_mass": 130680.0, "monoisotopic_mass": 130680.0 }, "refseq": { "ac": "XP_005169942", "name": "papilin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169942" }, "gene_names": [ { "name": "paplna", "type": "recommended", "evidence": [ { "id": "A0A8M9P0S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4" } ] }, { "name": "paplna", "type": "synonym", "evidence": [ { "id": "XP_005169942", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169942" } ] } ], "protein_names": [ { "name": "Papilin", "type": "recommended", "evidence": [ { "id": "A0A8M9P0S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4/entry#names_and_taxonomy" } ] }, { "name": "papilin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005169942", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169942" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005169942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169942" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0S4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "paplna", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070815-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070815-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd22635", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22635", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "562930", "url": "https://www.ncbi.nlm.nih.gov/gene/562930", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013273", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013273", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020901", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020901", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562930", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562930", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M1QL06", "url": "https://www.orthodb.org/?gene=A0A8M1QL06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P0S4", "url": "https://www.orthodb.org/?gene=A0A8M9P0S4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723:SF281", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723:SF281", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005169942", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169942", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M1QL06", "url": "https://www.uniprot.org/uniprotkb/A0A8M1QL06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1QL06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1QL06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P0S4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P0S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070815-4", "url": "https://zfin.org/ZDB-GENE-070815-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLAVAVCLQLFLASVFMQGIGDNWGEWSSYGECSRSCGGGVTMRTRRCVTHRTDGGHSCVGPDKSYRSCNIQDCPEGSRDFREEQCSQFDGTDFQGKRYKWLPYYGGENPCELNCIPRGENFYYRQKSSVVDGTPCRPGGKDICVDGLCKRLGCDHMLESPQEEDACLQCGGDGQSCSRLKNSFSMRNLPKGYNQMFIIPVGATTISIKETLPTRNYLAIKNLRGEYYLNGHWVIDLSRAASIAGTVLHYQRGREGEKSPEMITGRGPTTEPLVIELITQEVNEGVDYEYYLPNGGSTEGYYWSYGSWSACSKECGSGYQSRLVFCTFEDEAYSDYLCASLPRPLSNRTCNEQQCPQTRRMAYVYEAQLWRPTETPRVYVQVYSWTAGEWSPCPVTCGGGLQARRVECMSHDSTGSRLVEDSQCTAYTPRPLSQQNCNMQKCAQYSIYSWSQCSVTCGSGKQTRDVVCIGSDGASVEDYACGNQPKPPREQICEMPMCRSPIAWHIGDWGLCSKSCGSGLRERQVICSDRQRNLYRAEECQGKPKPPTVESCNAQPCYRPQEVPSMQDPTGHDNTLHGFMPYSEDPLLEIPQNNAAHSPHGTALTPHCSQTQYGCCPDGRTPASGPQHQGCPQDQGQPSCTWSRYGCCHDGVTVAQGQNMEGCPDAWTHWSSSSDTVPSAPVDCHSSTYGCCYDGVTAASGTHGEGCSNPPSNTQRSLSCDLPNTVGPCDQWTSRFYFDRSASRCLHFWYGGCHGNSNNFASEEECQKMCLRSELRQRDQAHVLSLQHGRRRFPAHVQLSSSGAHRAQRAHQPASNAMQQSNPAASWTAEGVSIDKTDPSTVEGLVGQRVVLPCRVTPPPSSAVLVEWRRDGVPVDPTRHEQQLDGSLLVGPITLQDSGWFLCVATRDDKRDHRYIYLSVSGSSQNNAGISEVDSSQSYTSQSSSRFNIDYSPLVEARAGQTAKLQCSVLPVSAIHAVTIHWSRAGQPLNSLRHSQHSDGTLVIKQLTADDSGLYTCTVTDAQKFEERQVQLRVLGDLRITKAPIDVDVVQGSTAQLACVVTGENVNVGWSRNGVPVRPDGHRVHVSADGTLILNNVQSVDEGTYTCNAYTGTLSVSAAAEIRLAKTPQQDIDGGQFSSSDCVDQPELANCKLIVYARLCSSPYYSSFCCSSCARYATDRLRRTHSR", "length": 1187, "header": "tr|A0A8M9P0S4-1|A0A8M9P0S4_DANRE Isoform 1 of Papilin OS=Danio rerio OX=7955 GN=paplna PE=3 SV=1 CANONICAL=A0A8M9P0S4-1" }, "isoforms": [ { "isoform_ac": "A0A8M1QL06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4/entry#A0A8M1QL06-1", "sequence": { "sequence": "MLAVAVCLQLFLASVFMQGIGDNWGEWSSYGECSRSCGGGVTMRTRRCVTHRTDGGHSCVGPDKSYRSCNIQDCPEGSRDFREEQCSQFDGTDFQGKRYKWLPYYGGENPCELNCIPRGENFYYRQKSSVVDGTPCRPGGKDICVDGLCKRLGCDHMLESPQEEDACLQCGGDGQSCSRLKNSFSMRNLPKGYNQMFIIPVGATTISIKETLPTRNYLAIKNLRGEYYLNGHWVIDLSRAASIAGTVLHYQRGREGEKSPEMITGRGPTTEPLVIELITQEVNEGVDYEYYLPNGGSTEGYYWSYGSWSACSKECGSGYQSRLVFCTFEDEAYSDYLCASLPRPLSNRTCNEQQCPQTRSWTAGEWSPCPVTCGGGLQARRVECMSHDSTGSRLVEDSQCTAYTPRPLSQQNCNMQKCAQYSIYSWSQCSVTCGSGKQTRDVVCIGSDGASVEDYACGNQPKPPREQICEMPMCRSPIAWHIGDWGLCSKSCGSGLRERQVICSDRQRNLYRAEECQGKPKPPTVESCNAQPCYRPQEVPSMQDPTGHDNTLHGFMPYSEDPLLEIPQNNAAHSPHGTALTPHCSQTQYGCCPDGRTPASGPQHQGCPQDQGQPSCTWSRYGCCHDGVTVAQGQNMEGCPDAWTHWSSSSDTVPSAPVDCHSSTYGCCYDGVTAASGTHGEGCSNPPSNTQRSLSCDLPNTVGPCDQWTSRFYFDRSASRCLHFWYGGCHGNSNNFASEEECQKMCLRSELRQRDQAHVLSLQHGRRRFPAHVQLSSSGAHRAQRAHQPASNAMQQSNPAASWTAEGVSIDKTDPSTVEGLVGQRVVLPCRVTPPPSSAVLVEWRRDGVPVDPTRHEQQLDGSLLVGPITLQDSGWFLCVATRDDKRDHRYIYLSVSGSSQNNAGISEVDSSQSYTSQSSSRFNIDYSPLVEARAGQTAKLQCSVLPVSAIHAVTIHWSRAGQPLNSLRHSQHSDGTLVIKQLTADDSGLYTCTVTDAQKFEERQVQLRVLGDLRITKAPIDVDVVQGSTAQLACVVTGENVNVGWSRNGVPVRPDGHRVHVSADGTLILNNVQSVDEGTYTCNAYTGTLSVSAAAEIRLAKTPQQDIDGGQFSSSDCVDQPELANCKLIVYARLCSSPYYSSFCCSSCARYATDRLRRTHSR", "length": 1163, "header": "tr|A0A8M1QL06-1|A0A8M9P0S4_DANRE Computationally mapped isoform of Papilin OS=Danio rerio OX=7955 GN=paplna PE=3 SV=1 CANONICAL=A0A8M9P0S4-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P0S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4/entry#A0A8M9P0S4-1", "sequence": { "sequence": "MLAVAVCLQLFLASVFMQGIGDNWGEWSSYGECSRSCGGGVTMRTRRCVTHRTDGGHSCVGPDKSYRSCNIQDCPEGSRDFREEQCSQFDGTDFQGKRYKWLPYYGGENPCELNCIPRGENFYYRQKSSVVDGTPCRPGGKDICVDGLCKRLGCDHMLESPQEEDACLQCGGDGQSCSRLKNSFSMRNLPKGYNQMFIIPVGATTISIKETLPTRNYLAIKNLRGEYYLNGHWVIDLSRAASIAGTVLHYQRGREGEKSPEMITGRGPTTEPLVIELITQEVNEGVDYEYYLPNGGSTEGYYWSYGSWSACSKECGSGYQSRLVFCTFEDEAYSDYLCASLPRPLSNRTCNEQQCPQTRRMAYVYEAQLWRPTETPRVYVQVYSWTAGEWSPCPVTCGGGLQARRVECMSHDSTGSRLVEDSQCTAYTPRPLSQQNCNMQKCAQYSIYSWSQCSVTCGSGKQTRDVVCIGSDGASVEDYACGNQPKPPREQICEMPMCRSPIAWHIGDWGLCSKSCGSGLRERQVICSDRQRNLYRAEECQGKPKPPTVESCNAQPCYRPQEVPSMQDPTGHDNTLHGFMPYSEDPLLEIPQNNAAHSPHGTALTPHCSQTQYGCCPDGRTPASGPQHQGCPQDQGQPSCTWSRYGCCHDGVTVAQGQNMEGCPDAWTHWSSSSDTVPSAPVDCHSSTYGCCYDGVTAASGTHGEGCSNPPSNTQRSLSCDLPNTVGPCDQWTSRFYFDRSASRCLHFWYGGCHGNSNNFASEEECQKMCLRSELRQRDQAHVLSLQHGRRRFPAHVQLSSSGAHRAQRAHQPASNAMQQSNPAASWTAEGVSIDKTDPSTVEGLVGQRVVLPCRVTPPPSSAVLVEWRRDGVPVDPTRHEQQLDGSLLVGPITLQDSGWFLCVATRDDKRDHRYIYLSVSGSSQNNAGISEVDSSQSYTSQSSSRFNIDYSPLVEARAGQTAKLQCSVLPVSAIHAVTIHWSRAGQPLNSLRHSQHSDGTLVIKQLTADDSGLYTCTVTDAQKFEERQVQLRVLGDLRITKAPIDVDVVQGSTAQLACVVTGENVNVGWSRNGVPVRPDGHRVHVSADGTLILNNVQSVDEGTYTCNAYTGTLSVSAAAEIRLAKTPQQDIDGGQFSSSDCVDQPELANCKLIVYARLCSSPYYSSFCCSSCARYATDRLRRTHSR", "length": 1187, "header": "tr|A0A8M9P0S4-1|A0A8M9P0S4_DANRE Isoform 1 of Papilin OS=Danio rerio OX=7955 GN=paplna PE=3 SV=1 CANONICAL=A0A8M9P0S4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 269, "start_aa": "Thr", "end_pos": 269, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr269", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 857, "start_aa": "Thr", "end_pos": 857, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr857", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:562930", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562930", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZD40-1", "protein_name": "Papilin", "gene_name": "Papln", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLASAQGCGYSGYPAPMPADSHRFFYCDAALGLQLLEPGCSERLQKLERVGTEMQLLLLLSLLLLLASTPGSWAQNVRRQSDTWGAWGEWSPCSRTCGGGISFRERPCYSQRRDGGASCVGPARSHRTCHTESCPDSVRDFRAEQCAEFDGTDFQGRRYRWLPYYAAPNKCELNCIPKGQNFYFKHRDAVVDGTPCEPGKRDICVEGVCRVVGCDHKLDSTKQEDKCLQCGGDGSSCYPITGTFDANDLSRGYNQIFIIPAGATSIHIEEADASRNFLAVKSIRGEYYLNGHWTIEEAQALPVASTVLQYERGVEGDLAPERLQARGPTSEPLVIELIIQESNPGVHYEYYLPVNDPGRSFSWSYGSWGDCSAECGGGHQSRLVFCTIDNEAYPDHMCQHQPRPAHRRSCNTHPCPKTKRWKVGPWTPCSVSCGGGFQSRSVYCVSSDGTGGQEAAEETQCAGLAGKPPTTQACNLQRCAVWSVEPWGECSVTCGAGIRKRSVTCRGDEDSLVHPAACSLKDQPTLTEPCVREACPGFRGQAWHVGSWSLCSKSCGSGIRRRQVVCTIGPPGRCVDLQSSKPAEVEACNRQPCHLPQEVPSIQDSRTHPSDRRMLSGPQVSPVADARDQQWATLERPRAQSNPREGQDSHLSSAGRAPTLQHPPHQPPLRPSSGARDCRHSPHGCCPDGHTPSLGPQWQGCPLAGASCLKSRYGCCPDGVSAAKGPQQAGCTRSHSSDNTGNRPGSRAVVSKDPKIHQSQAHPSEISECRSSQFGCCYDNVAFAAGPLGEGCVGQPSYAYPVRCLLPSAQGSCGDWAARWYFVGSVGRCNRFWYGGCHGNANNFATEQECMDTCRGQHGPRRPEAGAAGHRVHMDGGQRGPGGQQEPDWHRIEATVPRLPSPSGSPWSREQEPGPGQAPHIPAQGKRPRVPGLDRDARPPVRPTHSPSYRINLADSEPSLVQAAPGQAVQLFCPGNIPPEFQAGWQKEGRPISSNRYQLQADGSLIISPLRPEDAGIYSCGSQRSGHEPQKIQLRVTGGDMAVLSEVQPRHFPETRNPDPGHSPQNRGIGVGAEGHRVLSSSHPRPATRLRLDRTQPGVIDASPGQQIQLTCHAEGFPVPTIEWQRDGQLVSSPRHQVQHDGSLVISRVTVEDGGFYTCVAFNGHDRDQRWVQLRVQRELTITGLPPAMTVPEGDTARLLCVVAGDSVNIRWSRNGLPIQADGHRVHQSPDGTLLIHNLRPRDEGSYTCSAFRGSQAVSRSTEVKVALPAAPAAQSRDLGKDCIDQPELANCALILQAQLCGNEYYSSFCCASCSRFQPNAQPGWQQG", "length": 1328 }, "evidence": [ { "id": "HGNC:19262", "url": "https://alliancegenome.org/gene/HGNC:19262#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070815-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070815-4#orthology", "database": "AGR" }, { "id": "MGI:2386139", "url": "https://alliancegenome.org/gene/MGI:2386139#orthology", "database": "AGR" }, { "id": "RGD:1311176", "url": "https://alliancegenome.org/gene/RGD:1311176#orthology", "database": "AGR" }, { "id": "FB:FBgn0003137", "url": "https://alliancegenome.org/gene/FB:FBgn0003137#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95428-1", "protein_name": "Papilin", "gene_name": "PAPLN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLLLLVPLLLAPAPGSSAPKVRRQSDTWGPWSQWSPCSRTCGGGVSFRERPCYSQRRDGGSSCVGPARSHRSCRTESCPDGARDFRAEQCAEFDGAEFQGRRYRWLPYYSAPNKCELNCIPKGENFYYKHREAVVDGTPCEPGKRDVCVDGSCRVVGCDHELDSSKQEDKCLRCGGDGTTCYPVAGTFDANDLSRGYNQILIVPMGATSILIDEAAASRNFLAVKNVRGEYYLNGHWTIEAARALPAASTILHYERGAEGDLAPERLHARGPTSEPLVIELISQEPNPGVHYEYHLPLRRPSPGFSWSHGSWSDCSAECGGGHQSRLVFCTIDHEAYPDHMCQRQPRPADRRSCNLHPCPETKRWKAGPWAPCSASCGGGSQSRSVYCISSDGAGIQEAVEEAECAGLPGKPPAIQACNLQRCAAWSPEPWGECSVSCGVGVRKRSVTCRGERGSLLHTAACSLEDRPPLTEPCVHEDCPLLSDQAWHVGTWGLCSKSCSSGTRRRQVICAIGPPSHCGSLQHSKPVDVEPCNTQPCHLPQEVPSMQDVHTPASNPWMPLGPQESPASDSRGQWWAAQEHPSARGDHRGERGDPRGDQGTHLSALGPAPSLQQPPYQQPLRSGSGPHDCRHSPHGCCPDGHTASLGPQWQGCPGAPCQQSRYGCCPDRVSVAEGPHHAGCTKSYGGDSTGGMPRSRAVASTVHNTHQPQAQQNEPSECRGSQFGCCYDNVATAAGPLGEGCVGQPSHAYPVRCLLPSAHGSCADWAARWYFVASVGQCNRFWYGGCHGNANNFASEQECMSSCQGSLHGPRRPQPGASGRSTHTDGGGSSPAGEQEPSQHRTGAAVQRKPWPSGGLWRQDQQPGPGEAPHTQAFGEWPWGQELGSRAPGLGGDAGSPAPPFHSSSYRISLAGVEPSLVQAALGQLVRLSCSDDTAPESQAAWQKDGQPISSDRHRLQFDGSLIIHPLQAEDAGTYSCGSTRPGRDSQKIQLRIIGGDMAVLSEAELSRFPQPRDPAQDFGQAGAAGPLGAIPSSHPQPANRLRLDQNQPRVVDASPGQRIRMTCRAEGFPPPAIEWQRDGQPVSSPRHQLQPDGSLVISRVAVEDGGFYTCVAFNGQDRDQRWVQLRVLGELTISGLPPTVTVPEGDTARLLCVVAGESVNIRWSRNGLPVQADGHRVHQSPDGTLLIYNLRARDEGSYTCSAYQGSQAVSRSTEVKVVSPAPTAQPRDPGRDCVDQPELANCDLILQAQLCGNEYYSSFCCASCSRFQPHAQPIWQ", "length": 1278 }, "evidence": [ { "id": "HGNC:19262", "url": "https://alliancegenome.org/gene/HGNC:19262#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070815-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070815-4#orthology", "database": "AGR" }, { "id": "MGI:2386139", "url": "https://alliancegenome.org/gene/MGI:2386139#orthology", "database": "AGR" }, { "id": "RGD:1311176", "url": "https://alliancegenome.org/gene/RGD:1311176#orthology", "database": "AGR" }, { "id": "FB:FBgn0003137", "url": "https://alliancegenome.org/gene/FB:FBgn0003137#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q868Z9-1", "protein_name": "Papilin", "gene_name": "Ppn", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLSRRLCSTALVAFIVLASIHDSQSRFPGLRQKRQYGANMYLPESSVTPGGEGNDPDEWTPWSSPSDCSRTCGGGVSYQTRECLRRDDRGEAVCSGGSRRYFSCNTQDCPEEESDFRAQQCSRFDRQQFDGVFYEWVPYTNAPNPCELNCMPKGERFYYRQREKVVDGTRCNDKDLDVCVNGECMPVGCDMMLGSDAKEDKCRKCGGDGSTCKTIRNTITTKDLAPGYNDLLLLPEGATNIRIEETVPSSNYLACRNHSGHYYLNGDWRIDFPRPMFFANSWWNYQRKPMGFAAPDQLTCSGPISESLFIVMLVQEKNISLDYEYSIPESLSHSQQDTHTWTHHQFNACSASCGGGSQSRKVTCNNRITLAEVNPSLCDQKSKPVEEQACGTEPCAPHWVEGEWSKCSKGCGSDGFQNRSITCERISSSGEHTVEEDAVCLKEVGNKPATKQECNRDVKNCPKYHLGPWTPCDKLCGDGKQTRKVTCFIEENGHKRVLPEEDCVEEKPETEKSCLLTPCEGVDWIISQWSGCNACGQNTETRTAICGNKEGKVYPEEFCEPEVPTLSRPCKSPKCEAQWFSSEWSKCSAPCGKGVKSRIVICGEFDGKTVTPADDDSKCNKETKPESEQDCEGEEKVCPGEWFTGPWGKCSKPCGGGERVREVLCLSNGTKSVNCDEEKVEPLSEKCNSEACTEDEILPLTSTDKPIEDDEEDCDEDGIELISDGLSDDEKSEDVIDLEGTAKTETTPEAEDLMQSDSPTPYDEFESTGTTFEGSGYDSESTTDSGISTEGSGDDEETSEASTDLSSSTDSGSTSSDSTSSDSSSSISSDATSEAPASSVSDSSDSTDASTETTGVSDDSTDVSSSTEASASESTDVSGASDSTGSTNASDSTPESSTEASSSTDDSTDSSDNSSNVSESSTEASSSSVSDSNDSSDGSTDGVSSTTENSSDSTSDATSDSTASSDSTDSTSDQTTETTPESSTDSTESSTLDASSTTDASSTSESSSESSTDGSSTTSNSASSETTGLSSDGSTTDATTAASDNTDITTDGSTDESTDGSSNASTEGSTEGASEDTTISTESSGSTESTDAIASDGSTTEGSTVEDLSSSTSSDVTSDSTITDSSPSTEVSGSTDSSSSTDGSSTDASSTEASSTDVTESTDSTVSGGTSDTTESGPTEESTTEGSTESTTEGSTDSTQSTDLDSTTSDIWSTSDKDDESESSTPYSFDSEVTKSKPRKCKPKKSTCAKSEYGCCPDGKSTPKGPFDEGCPIAKTCADTKYGCCLDGVSPAKGKNNKGCPKSQCAETLFGCCPDKFTAADGENDEGCPETTTVPPTTTTEETQPETTTEIEGSGQDSTTSEPDTKKSCSFSEFGCCPDAETSAKGPDFEGCGLASPVAKGCAESENGCCPDGQTPASGPNGEGCSGCTRERFGCCPDSQTPAHGPNKEGCCLDTQFGCCPDNILAARGPNNEGCECHYTPYGCCPDNKSAATGYNQEGCACETTQYGCCPDKITAAKGPKHEGCPCETTQFGCCPDGLTFAKGPHHHGCHCTQTEFKCCDDEKTPAKGPNGDGCTCVESKFGCCPDGVTKATDEKFGGCENVQEPPQKACGLPKETGTCNNYSVKYYFDTSYGGCARFWYGGCDGNDNRFESEAECKDTCQDYTGKHVCLLPKSAGPCTGFTKKWYFDVDRNRCEEFQYGGCYGTNNRFDSLEQCQGTCAASENLPTCEQPVESGPCAGNFERWYYDNETDICRPFTYGGCKGNKNNYPTEHACNYNCRQPGVLKDRCALPKQTGDCSEKLAKWHFSESEKRCVPFYYSGCGGNKNNFPTLESCEDHCPRQVAKDICEIPAEVGECANYVTSWYYDTQDQACRQFYYGGCGGNENRFPTEESCLARCDRKPEPTTTTPATRPQPSRQDVCDEEPAPGECSTWVLKWHFDRKIGACRQFYYGNCGGNGNRFETENDCQQRCLSQEPPAPTPPRAPAPTRQPDPAPTVAQCSQPADPGQCDKWALHWNYNETEGRCQSFYYGGCGGNDNRFATEEECSARCSVNIDIRIGADPVEHDTSKCFLAFEPGNCYNNVTRWFYNSAEGLCDEFVYTGCGGNANNYATEEECQNECNDAQTTCALPPVRGRCSDLSRRWYFDERSGECHEFEFTGCRGNRNNFVSQSDCLNFCIGEPVVEPSAPTYSVCAEPPEAGECDNRTTAWFYDSENMACTAFTYTGCGGNGNRFETRDQCERQCGEFKGVDVCNEPVTTGPCTDWQTKYYFNTASQACEPFTYGGCDGTGNRFSDLFECQTVCLAGREPRVGSAKEICLLPVATGRCNGPSVHERRWYYDDEAGNCVSFIYAGCSGNQNNFRSFEACTNQCRPEPNKQDNEIGQNPCDTFDAECQELRCPYGVRRVAARSQPECTQCICENPCEGYSCPEGQQCAIDVASSDDRQFAPVCRDIYKPGECPALSANASGCARECYTDADCRGDNKCCSDGCGQLCVHPARPTQPPRTQAPVVSYPGDARAALEPKEAHELDVQTAIGGIAVLRCFATGNPAPNITWSLKNLVINTNKGRYVLTANGDLTIVQVRQTDDGTYVCVASNGLGEPVRREVALQVTEPVSQPAYIYGDKNVTQIVELNRPAVIRCPAGGFPEPHVSWWRNGQMFGLKNNLMARDYSLVFNSIQLSDLGLYTCEVYNQRRPVSLRVTLKAVGPVRPLSPEEEQYMQYVLNPATRPVTQRPSYPYRPTRPAYVPEPTVNVHAVLALEPKNSYTPGSTIVMSCSVQGYPEPNVTWIKDDVPLYNNERVQITYQPHRLVLSDVTSADSGKYTCRASNAYTYANGEANVSIQSVVPVSPECVDNPYFANCKLIVKGRYCSNPYYTQFCCRSCTLAGQVASPPLHPNAV", "length": 2898 }, "evidence": [ { "id": "HGNC:19262", "url": "https://alliancegenome.org/gene/HGNC:19262#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070815-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070815-4#orthology", "database": "AGR" }, { "id": "MGI:2386139", "url": "https://alliancegenome.org/gene/MGI:2386139#orthology", "database": "AGR" }, { "id": "RGD:1311176", "url": "https://alliancegenome.org/gene/RGD:1311176#orthology", "database": "AGR" }, { "id": "FB:FBgn0003137", "url": "https://alliancegenome.org/gene/FB:FBgn0003137#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9EPX2-1", "protein_name": "Papilin", "gene_name": "Papln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQLFPLLFSLLLTSTPGSWARNVRRQSDTWGTWGEWSPCSRTCGGGISFRERPCYSQRRDGGTSCVGPARSHRTCHTESCPDGVRDFRAEQCAEFDGTDFQGRRYRWLPYYAAPNKCELNCIPKGQNFYYKHKDAVVDGTPCEPGQRDICVDGVCRVVGCDHKLDSIKQEDKCLQCGGDGSSCYPVTGTFDGNDLSRGYNQIFIIPAGATSIRIEEAAASRNFLAVKSIRGEYYLNGHWTIEAAQALPVASTVLQYERGVEGDLAPERLQARGPTSEPLVIELLSQESNPGVHYEYYLPANDPGRGFSWSHGSWGDCSAECGGGHQSRLVFCTIDNEAYPDHMCQHQPRPTHRRSCNTQPCPKTKRWKVGPWTPCSVSCGGGVQSRSVYCISSDGTGGQEAAEETQCAGLVGKPPTTQACNLQHCAVWSVEPWGECSVTCGTGIRKRSVTCRGDEGSPVHAAACLLKDQPTLTEPCVQEACPVFRGQAWHVGSWSLCSKSCGSGIRRRQVVCTIGPPGRCVDLQSSKPAEMEACNRQPCHLPQEVPSIQDPRTRSSDPRMLSGPRVSPVSDGREQQWAPLERPRAQSNPREGQDPNLSSAGRAPTLQRPPHQPPLRPSSGPRDCRHSPHGCCPDGHTPSLGPQWQGCPLAGASCLQSRYGCCPDGVSAAEGPQQAGCTRSHGSDNTGNRPGSRAVASKNPKIHQPQAHEGEPSECRSSRFGCCYDNVASAAGPLGEGCVGQPSYAYPVRCLLPSAQGSCGDWAARWYFVASVGRCNRFWYGGCHGNANNFASEQECMNTCRGQHGPRRPEAGAAGHRAHVDGGQRGPGGQQEPDWHRAGATIPRLPSPSGSPWRREQEPAPGEPPHIPAYGNRPGGQEIRPRVPGLDREARPAVPPTHSPSYRIRLAGSEPSLVQAAPGQAVQLFCPGNIPSEFQAGWQKEGRPISSNRYQLQADGSLIISRLRPEDAGIYSCGSHRPGHEPQEIQLRVTGGDMAVFPEGQPRHFPEPRNPDLGHGPPHRGTGAEAGGHRVLSPSHPRPATRLRLDRTQPGVVDASPGQRIRLTCRAEGFPVPTIEWQRDGQLVSSPRHQVQPDGSLVISRVDVEDGGYYSCVAFNGQDRDQRWVQLRVLRELTITGLPPAVTVAEGDTARLLCVVAGESVNIRWSRNGLPIQADGHRVHQSPDGTLLIHNLRPRDEGSYTCSAFRGSQAVSRSTEVKVALPAPAAQSRDLGKDCIDQPELANCALILQAQLCGNEYYSSFCCASCSRFQPNAQPVWQQG", "length": 1280 }, "evidence": [ { "id": "HGNC:19262", "url": "https://alliancegenome.org/gene/HGNC:19262#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070815-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070815-4#orthology", "database": "AGR" }, { "id": "MGI:2386139", "url": "https://alliancegenome.org/gene/MGI:2386139#orthology", "database": "AGR" }, { "id": "RGD:1311176", "url": "https://alliancegenome.org/gene/RGD:1311176#orthology", "database": "AGR" }, { "id": "FB:FBgn0003137", "url": "https://alliancegenome.org/gene/FB:FBgn0003137#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0S4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0S4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4" } ], "pmid": "" }, { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0S4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0S4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P0S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4" }, { "id": "PS50279", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50279" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BPTI/Kunitz inhibitor", "eco_id": "ECO_0000259", "start_pos": 720, "end_pos": 770, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P0S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S4" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 823, "end_pos": 919, "start_aa": "Pro", 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"refseq": { "ac": "XP_017214401", "name": "uncharacterized protein col21a1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214401" }, "gene_names": [ { "name": "col21a1", "type": "recommended", "evidence": [ { "id": "A0A8M6Z2G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2G5" } ] }, { "name": "col21a1", "type": "synonym", "evidence": [ { "id": "XP_017214401", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214401" } ] } ], "protein_names": [ { "name": "Collagen alpha-1(XXI) chain", "type": "recommended", "evidence": [ { "id": "A0A8M6Z2G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2G5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein col21a1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017214401", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214401" } ] } ], "function": [ { "annotation": 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This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214401" } ] } ], "disease": [ { "disease_id": "DOID:12930", "recommended_name": { "id": "DOID:12930", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently." }, "synonyms": [ { "id": "DOID:12930", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12930", "name": "primary dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "Familial dilated cardiomyopathy with conduction defect due to LMNA mutation is a rare familial dilated cardiomyopathy characterized by left ventricular enlargement and/or reduced systolic function preceded or accompanied by significant conduction system disease and/or arrhythmias including bradyarrhythmias, supraventricular or ventricular arrhythmias. Disease onset is usually in early to mid-adulthood. Sudden cardiac death may occur and may be the presenting symptom. In some cases, it is associated with skeletal myopathy and elevated serum creatine kinase." }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "CDCD1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "LMNA familial isolated dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy dilated with conduction defect type 1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "familial dilated cardiomyopathy with conduction defect due to LMNA mutation", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "familial isolated dilated cardiomyopathy caused by mutation in LMNA", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, 1A", "description": "" }, { "id": "MIM:115200", "resource": "MIM", "url": "https://www.omim.org/entry/115200", "name": "Cardiomyopathy, dilated, 1A", "description": "Cardiomyopathy, dilated, 1A" } ], "unlinked_id_list": [], "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ] }, { "disease_id": "DOID:2468", "recommended_name": { "id": "DOID:2468", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2468", "name": "psychotic disorder", "description": "A cognitive disorder that involves abnormal thinking and perceptions resulting in a disconnection with reality." }, "synonyms": [ { "id": "DOID:2468", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2468", "name": "mental or behavioural disorder", "description": "" } ], "unlinked_id_list": [ "DOID:8646", "DOID:1203" ], "evidence": [ { "id": "2468", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2468" } ] }, { "disease_id": "DOID:9975", "recommended_name": { "id": "DOID:9975", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2G5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2G5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "col21a1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2G5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110607-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110607-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z2G5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z2G5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01472", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01472", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100333837", "url": "https://www.ncbi.nlm.nih.gov/gene/100333837", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050525", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050525", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100333837", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333837", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z2G5", "url": "https://www.orthodb.org/?gene=A0A8M6Z2G5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24020:SF90", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24020:SF90", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017214401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214401", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2G5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2G5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T719", "url": "https://www.uniprot.org/uniprotkb/A0AB32T719", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T719-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T719-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H3M7", "url": "https://www.uniprot.org/uniprotkb/A0AC58H3M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H3M7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H3M7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H3N2", "url": "https://www.uniprot.org/uniprotkb/A0AC58H3N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H3N2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H3N2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H3N8", "url": "https://www.uniprot.org/uniprotkb/A0AC58H3N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H3N8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H3N8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110607-3", "url": "https://zfin.org/ZDB-GENE-110607-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGCKMRSMHFVFWCLYFMLLHLFCTAQDEDMRLSCRTAPSDLVFILDGSWSVDDINFEIVKKWLVNITMSFNIGQKFTQVGVVQYSDDPFLHIPLGKHFSSSDLIKAMESIEYMGGNTNTGRAIKFANDKLFALSERGPNGIAKIAVVLTDGKSQDEVLAAAEAARKKGIILFAIGVGSETEEAQLRAIANKPSSTYVFSVKDYKAIAKIREVIRQKLCEETVCPAKIAINSRDEKGFDILLHLNLAKKAKKTQGSFYGSKAYQVTSRDDLSESTRMLFPGGLPPSYVFVATLKYKGSVAIEEWDLWRIQTKDEKPQMAVSLNGLDRTVMFTTTTSKTPSGTQTVVFTKSPAKKLFDEKWHQLRLLVTEEDVTLYVDDLEIETLALEPPDGIFINGKTQVGKYVSKETTVPFEVQKLRIYCDPEQNNRETACEIPGVCANGPGDIDPTPEPCICPPGPPGTPGMTGERGKMGDPGQPGPAGADGKPGVPGFRGSPGIQGSPGIEGQRGADGHKGEKGSPGEAGDRGIPGLPGPPGKTGEKGSAGNQGIQGPPGKDGQTGEKGSRGLAGPPGYPGEPGAPGRDGKDGAPGAIGLKGDPGPPGIPGLDGREGHPGMPGIPGNDGQRGIKGEAGLSGSKGAKGIPGDAGEMGLPGMTGSSGQPGPKGNKGESGESGQAGPPGPEGKPGADGPSGQPGHPGMPGSLGMKGQRGDTGERGADGMKGERGDSGRPGGHGLPGAAGKKGEKGTAGEPGQSGLNGHQGLPGQRGQTGPSGPRGQSGEIGHPGPPGPEGRPGREMSEQHIQQICRDILRSEIPALLLSSQHSQHRSCEHCYTRVGPPGPVGTPGPHGPRGFPGLSGSNGLQGQRGLPGRPGVPGMKGDPGEKGDKGSQGRSVIGDPGLPGPPGPTGPAGVGKPGQAGKPGSPGHEGKEGKRGQSGEPGQPGVCHPAMCYGAMIRRDPFSKGPNY", "length": 965, "header": "tr|A0A8M6Z2G5-1|A0A8M6Z2G5_DANRE Isoform 1 of Collagen alpha-1(XXI) chain OS=Danio rerio OX=7955 GN=col21a1 PE=3 SV=1 CANONICAL=A0A8M6Z2G5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z2G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2G5/entry#A0A8M6Z2G5-1", "sequence": { "sequence": "MGCKMRSMHFVFWCLYFMLLHLFCTAQDEDMRLSCRTAPSDLVFILDGSWSVDDINFEIVKKWLVNITMSFNIGQKFTQVGVVQYSDDPFLHIPLGKHFSSSDLIKAMESIEYMGGNTNTGRAIKFANDKLFALSERGPNGIAKIAVVLTDGKSQDEVLAAAEAARKKGIILFAIGVGSETEEAQLRAIANKPSSTYVFSVKDYKAIAKIREVIRQKLCEETVCPAKIAINSRDEKGFDILLHLNLAKKAKKTQGSFYGSKAYQVTSRDDLSESTRMLFPGGLPPSYVFVATLKYKGSVAIEEWDLWRIQTKDEKPQMAVSLNGLDRTVMFTTTTSKTPSGTQTVVFTKSPAKKLFDEKWHQLRLLVTEEDVTLYVDDLEIETLALEPPDGIFINGKTQVGKYVSKETTVPFEVQKLRIYCDPEQNNRETACEIPGVCANGPGDIDPTPEPCICPPGPPGTPGMTGERGKMGDPGQPGPAGADGKPGVPGFRGSPGIQGSPGIEGQRGADGHKGEKGSPGEAGDRGIPGLPGPPGKTGEKGSAGNQGIQGPPGKDGQTGEKGSRGLAGPPGYPGEPGAPGRDGKDGAPGAIGLKGDPGPPGIPGLDGREGHPGMPGIPGNDGQRGIKGEAGLSGSKGAKGIPGDAGEMGLPGMTGSSGQPGPKGNKGESGESGQAGPPGPEGKPGADGPSGQPGHPGMPGSLGMKGQRGDTGERGADGMKGERGDSGRPGGHGLPGAAGKKGEKGTAGEPGQSGLNGHQGLPGQRGQTGPSGPRGQSGEIGHPGPPGPEGRPGREMSEQHIQQICRDILRSEIPALLLSSQHSQHRSCEHCYTRVGPPGPVGTPGPHGPRGFPGLSGSNGLQGQRGLPGRPGVPGMKGDPGEKGDKGSQGRSVIGDPGLPGPPGPTGPAGVGKPGQAGKPGSPGHEGKEGKRGQSGEPGQPGVCHPAMCYGAMIRRDPFSKGPNY", "length": 965, "header": "tr|A0A8M6Z2G5-1|A0A8M6Z2G5_DANRE Isoform 1 of Collagen alpha-1(XXI) chain OS=Danio rerio OX=7955 GN=col21a1 PE=3 SV=1 CANONICAL=A0A8M6Z2G5-1" }, "locus": {} }, { "isoform_ac": "A0AB32T719-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2G5/entry#A0AB32T719-1", "sequence": { "sequence": "MGCKMRSMHFVFWCLYFMLLHLFCTAQDEDMRLSCRTAPSDLVFILDGSWSVDDINFEIVKKWLVNITMSFNIGQKFTQVGVVQYSDDPFLHIPLGKHFSSSDLIKAMESIEYMGGNTNTGRAIKFANDKLFALSERGPNGIAKIAVVLTDGKSQDEVLAAAEAARKKGIILFAIGVGSETEEAQLRAIANKPSSTYVFSVKDYKAIAKIREVIRQKLCEETVCPAKIAINSRDEKGFDILLHLNLAKKAKKTQGSFYGSKAYQVTSRDDLSESTRMLFPGGLPPSYVFVATLKYKGSVAIEEWDLWRIQTKDEKPQMAVSLNGLDRTVMFTTTTSKTPSGTQTVVFTKSPAKKLFDEKWHQLRLLVTEEDVTLYVDDLEIETLALEPPDGIFINGKTQVGKYVSKETTVPFEVQKLRIYCDPEQNNRETACEIPGVCANGPGDIDPTPEPCICPPGPPGTPGMTGERGKMGDPGQPGPAGADGKPGVPGFRGSPGIQGSPGIEGQRGADGHKGEKGSPGEAGSAGNQGIQGPPGKDGQTGEKGSRGLAGPPGYPGEPGAPGRDGKDGAPGAIGLKGDPGPPGIPGLDGREGHPGMPGIPGNDGQRGIKGEAGLSGSKGAKGIPGDAGEMGLPGMTGSSGQPGPKGNKGESGESGQAGPPGPEGKPGADGPSGQPGHPGMPGSLGMKGQRGDTGERGADGMKGERGDSGRPGGHGLPGAAGKKGEKGTAGEPGQSGLNGHQGLPGQRGQTGPSGPRGQSGEIGHPGPPGPEGRPGREMSEQHIQQICRDILRSEIPALLLSSQHSQHRSCEHCYTRVGPPGPVGTPGPHGPRGFPGLSGSNGLQGQRGLPGRPGVPGMKGDPGEKGDKGSQGRSVIGDPGLPGPPGPTGPAGVGKPGQAGKPGSPGHEGKEGKRGQSGEPGQPGVCHPAMCYGAMIRRDPFSKGPNY", "length": 947, "header": "tr|A0AB32T719-1|A0A8M6Z2G5_DANRE Computationally mapped isoform of Collagen alpha-1(XXI) chain OS=Danio rerio OX=7955 GN=col21a1 PE=3 SV=1 CANONICAL=A0A8M6Z2G5-1" }, "locus": {} }, { "isoform_ac": "A0AC58H3M7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2G5/entry#A0AC58H3M7-1", "sequence": { "sequence": "MGCKMRSMHFVFWCLYFMLLHLFCTAQDEDMRLSCRTAPSDLVFILDGSWSVDDINFEIVKKWLVNITMSFNIGQKFTQVGVVQYSDDPFLHIPLGKHFSSSDLIKAMESIEYMGGNTNTGRAIKFANDKLFALSERGPNGIAKIAVVLTDGKSQDEVLAAAEAARKKGIILFAIGVGSETEEAQLRAIANKPSSTYVFSVKDYKAIAKIREVIRQKLCEETVCPAKIAINSRDEKGFDILLHLNLAKKAKKTQGSFYGSKAYQVTSRDDLSESTRMLFPGGLPPSYVFVATLKYKGSVAIEEWDLWRIQTKDEKPQMAVSLNGLDRTVMFTTTTSKTPSGTQTVVFTKSPAKKLFDEKWHQLRLLVTEEDVTLYVDDLEIETLALEPPDGIFINGKTQVGKYVSKETTVPFEVQKLRIYCDPEQNNRETACEIPGVCANGPGDIDPTPEPCICPPGPPGTPGMTGERGKMGDPGQPGPAGADGCARI", "length": 488, "header": "tr|A0AC58H3M7-1|A0AC58H3M7_DANRE Computationally mapped isoform of Collagen alpha-1(XXI) chain OS=Danio rerio OX=7955 GN=col21a1 PE=3 SV=1 CANONICAL=A0A8M6Z2G5-1" }, "locus": {} }, { "isoform_ac": "A0AC58H3N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2G5/entry#A0AC58H3N2-1", "sequence": { "sequence": "MGVPGFRGSPGIQGSPGIEGQRGADGHKGEKGSPGEAGDRGIPGLPGPPGKTGEKGSAGNQGIQGPPGKDGQTGEKGSRGLAGPPGYPGEPGAPGRDGKDGAPGAIGLKGDPGPPGIPGLDGREGHPGMPGIPGNDGQRGIKGEAGLSGSKGAKGIPGDAGEMGLPGMTGSSGQPGPKGNKGESGESGQAGPPGPEGKPGADGPSGQPGHPGMPGSLGMKGQRGDTGERGADGMKGERGDSGRPGGHGLPGAAGKKGEKGTAGEPGQSGLNGHQGLPGQRGQTGPSGPRGQSGEIGHPGPPGPEGRPGREMSEQHIQQICRDILRSEIPALLLSSQHSQHRSCEHCYTRVGPPGPVGTPGPHGPRGFPGLSGSNGLQGQRGLPGRPGVPGMKGDPGEKGDKGSQGRSVIGDPGLPGPPGPTGPAGVGKPGQAGKPGSPGHEGKEGKRGQSGEPGQPGVCHPAMCYGAMIRRDPFSKGPNY", "length": 480, "header": "tr|A0AC58H3N2-1|A0AC58H3N2_DANRE Computationally mapped isoform of Uncharacterized protein col21a1 isoform X4 OS=Danio rerio OX=7955 GN=col21a1 PE=4 SV=1 CANONICAL=A0A8M6Z2G5-1" }, "locus": {} }, { "isoform_ac": "A0AC58H3N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2G5/entry#A0AC58H3N8-1", "sequence": { "sequence": "MGVPGFRGSPGIQGSPGIEGQRGADGHKGEKGSPGEAGSAGNQGIQGPPGKDGQTGEKGSRGLAGPPGYPGEPGAPGRDGKDGAPGAIGLKGDPGPPGIPGLDGREGHPGMPGIPGNDGQRGIKGEAGLSGSKGAKGIPGDAGEMGLPGMTGSSGQPGPKGNKGESGESGQAGPPGPEGKPGADGPSGQPGHPGMPGSLGMKGQRGDTGERGADGMKGERGDSGRPGGHGLPGAAGKKGEKGTAGEPGQSGLNGHQGLPGQRGQTGPSGPRGQSGEIGHPGPPGPEGRPGREMSEQHIQQICRDILRSEIPALLLSSQHSQHRSCEHCYTRVGPPGPVGTPGPHGPRGFPGLSGSNGLQGQRGLPGRPGVPGMKGDPGEKGDKGSQGRSVIGDPGLPGPPGPTGPAGVGKPGQAGKPGSPGHEGKEGKRGQSGEPGQPGVCHPAMCYGAMIRRDPFSKGPNY", "length": 462, "header": "tr|A0AC58H3N8-1|A0AC58H3N8_DANRE Computationally mapped isoform of Uncharacterized protein col21a1 isoform X5 OS=Danio rerio OX=7955 GN=col21a1 PE=4 SV=1 CANONICAL=A0A8M6Z2G5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 448, "start_aa": "Thr", "end_pos": 448, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr448", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 461, "start_aa": "Thr", "end_pos": 461, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr461", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 843, "start_aa": "Thr", "end_pos": 843, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr843", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 906, "start_aa": "Thr", "end_pos": 906, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr906", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100333837", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333837", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q96P44-1", "protein_name": "Collagen alpha-1(XXI) chain", "gene_name": "COL21A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": 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"https://www.ncbi.nlm.nih.gov/protein/XP_021326787" } ] } ], "protein_names": [ { "name": "Partner and localizer of BRCA2", "type": "synonym", "evidence": [ { "id": "A0A8M9P7S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7S0/entry#names_and_taxonomy" } ] }, { "name": "partner and localizer of BRCA2", "type": "synonym", "evidence": [ { "id": "XP_021326787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326787" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326787" } ] } ], "disease": [ { "disease_id": "DOID:0050671", "recommended_name": { "id": "DOID:0050671", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050671", "name": "female breast cancer", "description": "A breast cancer that develops from breast tissue in females." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050671", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050671" } ] }, { "disease_id": "DOID:0111094", "recommended_name": { "id": "DOID:0111094", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111094", "name": "Fanconi anemia complementation group N", "description": "A Fanconi anemia that has_material_basis_in compound heterozygous mutation in the PALB2 gene on chromosome 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"length": 1275, "header": "tr|A0A8M9P7S0-1|A0A8M9P7S0_DANRE Isoform 1 of Partner and localizer of BRCA2 OS=Danio rerio OX=7955 GN=palb2 PE=4 SV=1 CANONICAL=A0A8M9P7S0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P7S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7S0/entry#A0A8M9P7S0-1", "sequence": { "sequence": "MSEEILHNEDKETLRRRLEQLKQEYERTAQRLQRAEHHDAIRRHRLTQIELSQTSEPSSAASSMSTSDHFENHQNLQLQTNRNISDFSAVEKTPAFQLQLAEITSTPSLYSPACKRSPAHRLRSKRSRLRLQNKERESDTDISQENIHERENAEIRECPNSKGNSLKKVKNEEKDFEKIKERDIEKEKCKDRPSRVKTDSKIVKPPQVLENDGKKEEHCVLNCSVSQSNDKLPVVSSIEIHLENQNADSSKAEVDLPLTDWPVKEELHFGPPVSISFFSQSAEATDKSVEMLKQTKQPSTKKDYDDKIDVKQSSFTSGVLDSCTLVEGLPFPVEYYVRTTRRMAASNSSIDLDAVIYSQLTGGRGRRRLSQSQLSSRGQVTPERLEPVCRTTDQQRGRGRGRRGRRGRRRTTVGPTSCANLTADSPESLNKSHDELLRQSELVLEGPQVESQSNDLHEPAVNLNPEQGATQDLKHLPDSQLYIDSQLIPDSNLYPIFRRKLGQTGLESQKGTNKYDQSPFLPSLTSLIQGLQEKKTTSGQVTLDDIQDFHLPDEDFGQLKLERLCLPTSIVEPFPQHHLAYKTRQSSRRQRARKCKTDAHFSVGELFTPEPIYISSLEDSLPHCQSDATDQSQTEIPKDPHAVNEISSALMNCTEPGECMNNERKVESSEAENIKGLQSQIQKQSDILLEKTSLSPVILKLSPSLTAHTQKSQDPVLPSLGMSPHFLTPASPLDLRSPLFSSSGILKSTSSVTLMGCVSPESVSAKTSENIKNSNFIKRGGRAEVQRGSRIQTPSKMTQESITKAQNNVKLNMSSQRNIALGYEHLKSPETPKRESSCISGNYLEHERSFDEESNLECGNKTKCTTENEAQLHNNPQLESINPVQNCESSKLWSETQSQTPFDKISLETSVNQRTERRNESEEFSSNNLTLFHEQTPFSDAGHFSTVLQEMHTFKALEDGCVLDLCLVRWPSEDCCICVAGQWSVCLWAQRKGDQTWSLSHSWTFAQSVMSLQAIADSSGLLCVTLGQLEIAEARVLCCPGNDGPFSQTVVCTDTLQAVVGVSNCRLVCCSTPGYQQRVSMLTLSQEGSVVKSLPFISAKQNIQTLAAVEGEKEALIGLTECKTLLIWSMKSGQLLQTICLEKTLTRTNCMKGYSYRGVLCVLLQNSGYVCDEESNTCLFTLVATNPLTGKHITLSSISHPDQPKQPLLDGDVSGSRLVGVFQNGHLAVWDLRESVAKATVVLDESCRLARWAGPDTLLTGYLNGDVSVFHYKSA", "length": 1275, "header": "tr|A0A8M9P7S0-1|A0A8M9P7S0_DANRE Isoform 1 of Partner and localizer of BRCA2 OS=Danio rerio OX=7955 GN=palb2 PE=4 SV=1 CANONICAL=A0A8M9P7S0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 416, "start_aa": "Thr", "end_pos": 416, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr416", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:558923", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558923", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZM14-1", "protein_name": "Partner and localizer of BRCA2", "gene_name": "Palb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEELSGKPLSCAEKEKLKEKLAFLRKEYTKTLARLQRAKRAEKVKNSKKAIEDCVPQQEISPQLSRSEPINKGFPCDASLQSDHLDEETGENISQILDGDPQSFNCESGQEVLHTPRAGDIQGQFLHSTSSPDGKKGQSAFPGTTKKLRKRSSVLQEKDDFFDTSSLVLPGRHQKRQETVSSKNPRAPEIEKTHLLCLKSQTPDPPALVTEIDGGGRLIVPSGKSERGIDTPVRGNNVSRETTVPSCTASDSNHSGHLELTPPNSGCKITTQGPASSINLVAQDKKTTIFTDNPVVYKPVSAGSQLPGSPNSCSVNDLTHSNLPANTTPNSRSLKSPDNIVDGRNENLEEDEIVGLSENLSPAAVSPPSTESQIHSCTMLEGLLFPAEYYVRTTRRMSDCQRKIALEAVIQSHLGVKKKERKKKNKATKNLVLSSEETDQSESGMLDTSIGHSSSESLSQKLISPVEVSSPLGPANNRSKKATARPPGRGHREKRTSACTSTLGHHQLLFPPCAALAVNRTRGKFTKHKCQNRDVIIHDFELPDEDFGPLKLEKLKSYSEKLIESPDSKNCGESLPTEGKHAVLEELQIDSETEGLEVELTVLPGEACHPGPTLRWQPVSKGLSSSIVLFTPTDTAAPNNSDRSTASLCSPAFPVLGRTPAFGSQATGENISAEAGQPCSTSRPSHLGETNSLVNKNKQCDSSACSPKLDTSLQVSGRQGQATCDSDSGPQATPLPIESFTFREDQLCGSACLELHEHSTEQTEIADLPACDSLSPGNLQLVSELKNPSSSCSVDVSAMWWERAGTKEPCIITACEDVVSLWKPLDSMQWEKVHTWHFTEVPVLQIVPVPDIYSLICVALGSLEIREIRALLCSSGDECEKQVLLQSGDIKAMLGLTKRRLVSSTGTFCNQQIQIMTFAEDGSSKDEQLLMPPDETILTFAEVHGMQEALLGTTTVNSIVIWNLKTGQLLKKMHIDDSYQTCVCHRAYSEMGLLFIVLSHPCAKESQAFGSPVFQLLAINPMTAQSVGVLLCSLPQGQAGRFLEGDVKDHVAAAVLTSGTIAIWDLLLGHCTALLPPVSDQSWSLVKWSGTDSHLLAGQKDGNIFIYRYF", "length": 1110 }, "evidence": [ { "id": "HGNC:26144", "url": "https://alliancegenome.org/gene/HGNC:26144#orthology", "database": "AGR" }, { "id": "RGD:1304759", "url": "https://alliancegenome.org/gene/RGD:1304759#orthology", "database": "AGR" }, { "id": "MGI:3040695", "url": "https://alliancegenome.org/gene/MGI:3040695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-43#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3U0P1-1", "protein_name": "Partner and localizer of BRCA2", "gene_name": "Palb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEELSGKPLSYAEKEKLKEKLAFLKKEYSRTLARLQRAKRAEKAKNSKKAIEDGVPQPEASSQLSHSESINKGFPCDTLQSNHLDEETGENISQILDVEPQSFNCKQGKEVLHTPRAGDIQGQLLHSTSSPDGKKEQNTLPGTTKTPWEKSSVSQEKEDYFDTNSLALLGKHRKGQESISRKNSRTPVSEKTHLLSLRSQIPDPPALVTGIGEGILIPPSGKSERGIDTLVRGNTVSAEAAVPSCTASNSNHSQHLEHTPPKSGCKITTQGPASSTNLVAQDQKMTIFTVNSVVYKAVRAHGQLPGSPNSCSVNDLTHSNLPANSTPNSKSLKSPSNTVDERNEPLQEDEILGPSKNFNLAAVSPPSTESQIHSCTMLEGLLFPAEYYVRTTRRMSDCQRKIALEAVIQSHLGVKKKELKKKTKATKAVVLSSEDTDQSESGMLDTSTGQSSSGSLSQKLLSPAEVSSPPGPAGKATTPPPGRGHRGKRKSARTSTLGHCQLLFPPCAALAVNRSKGKFTKHKCQNRGVVIHDFELPDEDFGLLKLEKLKSCSEKLIESPDSKNCGERLPREGNHAALEELQRDSETEGLEEELTVPPGEAYRPGPTLRRQPGSKDLSSSIVLFTPADTAAPNDSGRPPPSLCSPAFPILGMTPALGSQAAGETLSTEAAQPCSTSQPPLLGDTNSLVNNSKQCNSSACSPKPDTNLQASGRQGQPACDSDSGPQATPLPVESFTFRENQLCGNACLELHEHSTEQTETADRPACDNLNPGNLQLVSELKNPSSSCSVDVSAMWWERAGAKEPCIVTACEDVVSLWKPLNSLQWEKVHTWHFTEVPVLQIVPVPDVYNLICVALGSLEIREIRALLCSSGDDSEKQVLLKSGDIKAMLGLTKRRLVSSTGTFCNQQIQIMTFADDGSSKDEQLLMPPDETVLTFAEVQGTQEALLGTTTVNSIVIWNLKTGQLLKKMHIDDSYQASVCHGAYSEKGLLFVVVSQPCAKESQALGSPVFQLLVINPKTAQSVGVLLCSLPQGQAGRFLEGDVKDHVAAAVLTSGTIAIWDLLLGHCTALLPPVSDQSWSLVKWSGTDSHLLAGQKDGNIFIYRYF", "length": 1104 }, "evidence": [ { "id": "HGNC:26144", "url": "https://alliancegenome.org/gene/HGNC:26144#orthology", "database": "AGR" }, { "id": "RGD:1304759", "url": "https://alliancegenome.org/gene/RGD:1304759#orthology", "database": "AGR" }, { "id": "MGI:3040695", "url": "https://alliancegenome.org/gene/MGI:3040695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-43#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86YC2-1", "protein_name": "Partner and localizer of BRCA2", "gene_name": "PALB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDEPPGKPLSCEEKEKLKEKLAFLKREYSKTLARLQRAQRAEKIKHSIKKTVEEQDCLSQQDLSPQLKHSEPKNKICVYDKLHIKTHLDEETGEKTSITLDVGPESFNPGDGPGGLPIQRTDDTQEHFPHRVSDPSGEQKQKLPSRRKKQQKRTFISQERDCVFGTDSLRLSGKRLKEQEEISSKNPARSPVTEIRTHLLSLKSELPDSPEPVTEINEDSVLIPPTAQPEKGVDTFLRRPNFTRATTVPLQTLSDSGSSQHLEHIPPKGSSELTTHDLKNIRFTSPVSLEAQGKKMTVSTDNLLVNKAISKSGQLPTSSNLEANISCSLNELTYNNLPANENQNLKEQNQTEKSLKSPSDTLDGRNENLQESEILSQPKSLSLEATSPLSAEKHSCTVPEGLLFPAEYYVRTTRSMSNCQRKVAVEAVIQSHLDVKKKGFKNKNKDASKNLNLSNEETDQSEIRMSGTCTGQPSSRTSQKLLSLTKVSSPAGPTEDNDLSRKAVAQAPGRRYTGKRKSACTPASDHCEPLLPTSSLSIVNRSKEEVTSHKYQHEKLFIQVKGKKSRHQKEDSLSWSNSAYLSLDDDAFTAPFHRDGMLSLKQLLSFLSITDFQLPDEDFGPLKLEKVKSCSEKPVEPFESKMFGERHLKEGSCIFPEELSPKRMDTEMEDLEEDLIVLPGKSHPKRPNSQSQHTKTGLSSSILLYTPLNTVAPDDNDRPTTDMCSPAFPILGTTPAFGPQGSYEKASTEVAGRTCCTPQLAHLKDSVCLASDTKQFDSSGSPAKPHTTLQVSGRQGQPTCDCDSVPPGTPPPIESFTFKENQLCRNTCQELHKHSVEQTETAELPASDSINPGNLQLVSELKNPSGSCSVDVSAMFWERAGCKEPCIITACEDVVSLWKALDAWQWEKLYTWHFAEVPVLQIVPVPDVYNLVCVALGNLEIREIRALFCSSDDESEKQVLLKSGNIKAVLGLTKRRLVSSSGTLSDQQVEVMTFAEDGGGKENQFLMPPEETILTFAEVQGMQEALLGTTIMNNIVIWNLKTGQLLKKMHIDDSYQASVCHKAYSEMGLLFIVLSHPCAKESESLRSPVFQLIVINPKTTLSVGVMLYCLPPGQAGRFLEGDVKDHCAAAILTSGTIAIWDLLLGQCTALLPPVSDQHWSFVKWSGTDSHLLAGQKDGNIFVYHYS", "length": 1186 }, "evidence": [ { "id": "HGNC:26144", "url": "https://alliancegenome.org/gene/HGNC:26144#orthology", "database": "AGR" }, { "id": "RGD:1304759", "url": "https://alliancegenome.org/gene/RGD:1304759#orthology", "database": "AGR" }, { "id": "MGI:3040695", "url": "https://alliancegenome.org/gene/MGI:3040695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-43#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7S0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "double-strand break repair via homologous recombination", "id": "GO:0000724", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000724", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P7S0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7S0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 420, "end_pos": 422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" }, { "start_pos": 860, "end_pos": 862, "annotation": "n_glycosylation_sequon" }, { "start_pos": 919, "end_pos": 921, "annotation": "n_glycosylation_sequon" }, { "start_pos": 928, "end_pos": 930, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P7S0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7S0" }, { "id": "PF16756", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16756" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Partner and localiser of BRCA2 WD40", "eco_id": "ECO_0000259", "start_pos": 948, "end_pos": 1270, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 416 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 420, "end_pos": 422 }, { "start_pos": 430, "end_pos": 432 }, { "start_pos": 652, "end_pos": 654 }, { "start_pos": 812, "end_pos": 814 }, { "start_pos": 83, "end_pos": 85 }, { "start_pos": 860, "end_pos": 862 }, { "start_pos": 919, "end_pos": 921 }, { "start_pos": 928, "end_pos": 930 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PAD7-1", "uniprot_ac": "A0A8M9PAD7", "uniprot_id": "A0A8M9PAD7_DANRE", "mass": { "chemical_mass": 45997.0, "monoisotopic_mass": 45997.0 }, "refseq": { "ac": "XP_021327982", "name": "zona pellucida-like domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327982" }, "gene_names": [ { "name": "si:ch211-103f14.3", "type": "recommended", "evidence": [ { "id": "A0A8M9PAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAD7" } ] }, { "name": "si:ch211-103f14.3", "type": "synonym", "evidence": [ { "id": "XP_021327982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327982" } ] } ], "protein_names": [ { "name": "Zona pellucida-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8M9PAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAD7/entry#names_and_taxonomy" } ] }, { "name": "zona pellucida-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_021327982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327982" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021327982.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021327982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327982" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PAD7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAD7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-103f14.3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAD7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110411-160", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-160", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PAD7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PAD7", "database": "AlphaFoldDB", "categories": [] }, { "id": "101884180", "url": 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"PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00100", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00100", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021327982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327982", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PAD7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110411-160", "url": "https://zfin.org/ZDB-GENE-110411-160", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRQGLHSANRRKYILLNIFLFLLIPKFNKSIFLSSNCGSDYRIPEYTDISVDCGTEYISLAIRFCPVVFSGYNESQLILNSVVNDPDCEGVVDTFASPPVVRYTFSINSSNNCGSNFVTYRGAGTGLFSDFSNIETVNISGVVRSLDITTSTVTYKLQLRYYYSCSYPLEYLINNTQIDVLGTSIAVKDNNGSFISTLSLKLFRDLNYTQPLIIPPHGIHLKTNVFVQVEATNLTSNYFLLLDRCFASVSNKPVTKTFYDLFLACGMNRLTKMLTNGEMQVARFSFPAFRFTEQYNQSVSTYYLHCITRLCEITTCAAYRQCRKRKKRDVSPSGVTDATTITSPAIIISADDVVATKEEDVTISTKQPSDSTVGIGVAVCILAFSCITIIVIGAIFYKRHWDNKPSKTPAVS", "length": 412, "header": "tr|A0A8M9PAD7-1|A0A8M9PAD7_DANRE Isoform 1 of Zona pellucida-like domain-containing protein 1 OS=Danio rerio OX=7955 GN=si:ch211-103f14.3 PE=4 SV=2 CANONICAL=A0A8M9PAD7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAD7/entry#A0A8M9PAD7-1", "sequence": { "sequence": "MRQGLHSANRRKYILLNIFLFLLIPKFNKSIFLSSNCGSDYRIPEYTDISVDCGTEYISLAIRFCPVVFSGYNESQLILNSVVNDPDCEGVVDTFASPPVVRYTFSINSSNNCGSNFVTYRGAGTGLFSDFSNIETVNISGVVRSLDITTSTVTYKLQLRYYYSCSYPLEYLINNTQIDVLGTSIAVKDNNGSFISTLSLKLFRDLNYTQPLIIPPHGIHLKTNVFVQVEATNLTSNYFLLLDRCFASVSNKPVTKTFYDLFLACGMNRLTKMLTNGEMQVARFSFPAFRFTEQYNQSVSTYYLHCITRLCEITTCAAYRQCRKRKKRDVSPSGVTDATTITSPAIIISADDVVATKEEDVTISTKQPSDSTVGIGVAVCILAFSCITIIVIGAIFYKRHWDNKPSKTPAVS", "length": 412, "header": "tr|A0A8M9PAD7-1|A0A8M9PAD7_DANRE Isoform 1 of Zona pellucida-like domain-containing protein 1 OS=Danio rerio OX=7955 GN=si:ch211-103f14.3 PE=4 SV=2 CANONICAL=A0A8M9PAD7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101884180", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884180", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAD7" }, { "id": "PS51034", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51034" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZP", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 329, "start_aa": "Asp", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 138, "end_pos": 140 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 191, "end_pos": 193 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 28, "end_pos": 30 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PD42-1", "uniprot_ac": "A0A8M9PD42", "uniprot_id": "A0A8M9PD42_DANRE", "mass": { "chemical_mass": 96674.0, "monoisotopic_mass": 96674.0 }, "refseq": { "ac": "XP_021328992", "name": "extracellular calcium-sensing receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328992" }, "gene_names": [ { "name": "olfcq20", "type": "recommended", "evidence": [ { "id": "A0A8M9PD42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD42" } ] }, { "name": "olfcq20", "type": "synonym", "evidence": [ { "id": "XP_021328992", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328992" } ] } ], "protein_names": [ { "name": "Extracellular calcium-sensing receptor", "type": "synonym", "evidence": [ { "id": "A0A8M9PD42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD42/entry#names_and_taxonomy" } ] }, { "name": "extracellular calcium-sensing receptor", "type": "synonym", "evidence": [ { "id": "XP_021328992", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328992" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021328992.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328992", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328992" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD42" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "olfcq20", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD42", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PD42", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PD42", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06364", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06364", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100004085", "url": "https://www.ncbi.nlm.nih.gov/gene/100004085", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100004085", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004085", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24061", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061:SF418", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061:SF418", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021328992", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328992", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PD42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PD42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-208", "url": "https://zfin.org/ZDB-GENE-060503-208", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MWITLCIYLYLSLNYICAHSILRTSDSCRLQRRFHLNGMYKDGDVILGGLFQVHFFTVFPEQSFRTEPEPPFCEKFDMESFQQAQTMAFAIEEINKNPNLLPNITLGFHLYDNCVRLGMAFRAAISLASGTEESFQNLNCTGPPPVIGIVGDPSSTPSIAISSLLGLFRVPIVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLIYSDDDYGVYAAQSFHLEMQMFGHCVAFSEILPHNNNQRDIQRIMGVIQASTARVVVVFSTSSFLLPLIDEVASQNMTGRQWIASEAWATSPVYHSPRLLPFLGGTLGIAVRHGEIPGLHDFLLHLGPGNESRNNMLRIFWENMFGCSFEPGVKDTNSEIKLCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHGLHDLMQCEKGRGPFRGESCADITNLKPWQLVHYLQKVNFTTGFGDHVSFDENGDALAIYDVLNWQPSSDGSIQIFTVGVVKERTETGMVLTIDEDAIYWNFETKKSPQSVCSESCSPGTRRATRKGLPVCCFDCLPCRDGEISNTTDAIECMLCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGSCFCVLVMIIFGLHRNTPIVRANNSELSFMLLLSLKMCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGAMKWFGAAQQRCTVLVLTVLQVVICSVWLSTASPTPYKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKNAIMGRETQKR", "length": 867, "header": "tr|A0A8M9PD42-1|A0A8M9PD42_DANRE Isoform 1 of Extracellular calcium-sensing receptor OS=Danio rerio OX=7955 GN=olfcq20 PE=3 SV=2 CANONICAL=A0A8M9PD42-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PD42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD42/entry#A0A8M9PD42-1", "sequence": { "sequence": "MWITLCIYLYLSLNYICAHSILRTSDSCRLQRRFHLNGMYKDGDVILGGLFQVHFFTVFPEQSFRTEPEPPFCEKFDMESFQQAQTMAFAIEEINKNPNLLPNITLGFHLYDNCVRLGMAFRAAISLASGTEESFQNLNCTGPPPVIGIVGDPSSTPSIAISSLLGLFRVPIVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLIYSDDDYGVYAAQSFHLEMQMFGHCVAFSEILPHNNNQRDIQRIMGVIQASTARVVVVFSTSSFLLPLIDEVASQNMTGRQWIASEAWATSPVYHSPRLLPFLGGTLGIAVRHGEIPGLHDFLLHLGPGNESRNNMLRIFWENMFGCSFEPGVKDTNSEIKLCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHGLHDLMQCEKGRGPFRGESCADITNLKPWQLVHYLQKVNFTTGFGDHVSFDENGDALAIYDVLNWQPSSDGSIQIFTVGVVKERTETGMVLTIDEDAIYWNFETKKSPQSVCSESCSPGTRRATRKGLPVCCFDCLPCRDGEISNTTDAIECMLCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGSCFCVLVMIIFGLHRNTPIVRANNSELSFMLLLSLKMCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGAMKWFGAAQQRCTVLVLTVLQVVICSVWLSTASPTPYKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKNAIMGRETQKR", "length": 867, "header": "tr|A0A8M9PD42-1|A0A8M9PD42_DANRE Isoform 1 of Extracellular calcium-sensing receptor OS=Danio rerio OX=7955 GN=olfcq20 PE=3 SV=2 CANONICAL=A0A8M9PD42-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 156, "start_aa": "Thr", "end_pos": 156, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr156", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100004085", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004085", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KAL5-1", "protein_name": "Vomeronasal 2 receptor 19 like 1", "gene_name": "Vom2r19l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTMIFLFLLLNIPLLMVDFIHPRCFWRMKQNEDKDGNPGTGCTFFLQSVHWPVEKEYYSDIFNIQMHNENHKYALALAFAIYEINGNPDLLPNMSLIFEFTRDVCDWESQLNSVIQSSLKNHNILPNYICKEFTKCPMALTGLNWTTTLKLHTILNNFISQQFLQVTYGPFHPVLSDNEKFPYLYQMASDDKSLALALVSFIIHFGWNWVGLAISNNDQGIQFLSYLRREMEKGTVCFAFVNMIPVNMHLYMSRAEMYYNQIMTSSTNVVILYGDTDSTLAVSFRMWESLGIEKIWVTNSWWAATLSKKDHTFDNLYGTYAFGQHHGEISGFKNFVQTLNPAKYSDEHLVKLEWMYFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFTGGSYDIYNAVYSFAHALHEMTFQIFDNLPKDNGREHNYSCKKLCSFLRKTSFTNPVGDRVNMNQRHKQKEEYDIFYIWNFPQGLGIKVKIGMFSPYFPNGQQLHLSEDVLEWAKGSAQMPTSACSADCGPGFRKSWKDGMATCCFHCKPCPENEISNETNVDVCARCPDDQYANIEQNRCIPKAVVFLSYEEPLGMALSLISLGFSVFTIVLLGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSAICILQQITFGVVFTVSVSTVLAKTITVILAFKVTASQRMMKYFLVSRVPNYIIPTFTLFQVILCAVWLGASPPSIDIDAKSEHGHIIIACHKGSVTTFYCVLGYLGTLASGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKIMVAVEIFSTLASSAGMLGCIFVPKCYTVLFRQDQNSLVMIRMKSSSHAHIS", "length": 857 }, "evidence": [ { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0R4IS27-1", "protein_name": "Olfactory receptor CG6 precursor", "gene_name": "olfcg6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFLFYTILLFHLLHTKVENSLCRIMGDSNYPLFSKNGDVSIGGIFAIHRKETLPSFEFMQKPQPLSCSSVNLRDFRLAQTMIFAVEEINRSKSLLPNVSIGYKIYDTCGSRLSTMTAIMGLMNGQDFSTEDRCNGQSRLHAIIGESESSATIVLSRTTGPFRIPVISHSSSCECLSNKKDYPSFFRTISSDYHMSRALVYIVKHLDWSWVGAVNSDNDYGNNGMAIFLKAAHEEGICVEYSVKFYRTEPEKLKKVVDTINKGTAKVIVAFVSFVEMGLLIDQLSIQNITGIQMIGVEPWITANTYITSNSFRAMGGSLGFATKYIYIEGFAEYVMTPFWNTAFPCSESDRNHSHYELICSRYEDLLALKNDNKDVNEHRYSSNVYKAVYAVAHSLHGLLNCKEQEGCEKGLTIQPQQVVKALKNINFTIKSGDSVWFDNTGSVVALYEVVNWQKDSDGSFQFKSVGFYDAMMPPYKNLRLNTKNIVWAGGQLEKPRSVCSESCAPGTRKAAQKGRPVCCYDCIPCAEGEISNETDSINCKQCPGEYWSNTERNRCVIKAVEFLSFSEVMGIVLVIFSLFGAGLTVLVAVLFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTKWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPVQQRLSVFAFTLIQVLICVLWLTISPPFPYKNMKYYKEKIILECNLGNTIGFWAVLGYIGLLAALCFLLAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSFGLLVSIFAPKCFIILLKPEQNTKQHVMGKTTCSL", "length": 837 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A3B2W422-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r54", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSASMWGYRVTQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQKEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSYQSLGKIEETVQKMQKCTAKVVLVFLSNLNFQLILRGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVSSLNAEETVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFVLALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQICLSPGTSTFVVLIASLIQVVLCGVWLATSPPFPDKDMISEPQHIVIQCQEGSGATFFCVLGYLGFLAGGTFSVAFLARGLPDIFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLKQGYCAQQEKQGEMLQRRYKFSGESPEPNI", "length": 878 }, "evidence": [ { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W4A7-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r53", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCTLLSVLFGCLSGSALSGPRVWIIPRQSPRFDRPGDVIVGGSFSIFHFSDGTLSNFTAPPPVLKTSSASMWSYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTCSHAVTQLVIHFQWSWVIILAHDDDFGQQASSLATQMLTPAGVCIEYHLHVPSHQSFGKIEETVQKMQKCTARVVLVFLSNSNFQLILHGLLAVPVSGQVWVSMDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSRIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHNLRNVYFKTSDGNKIMFDANGDLVTQFDIFQGKKTPAGVFHLVHVGLIDPQASSGNKMMVQLKQDLQVSSLNAEITVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTIFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQVCLSSGASTSVVLIASLIQVVLCGIWLITSPPFPDRDMISEPRHTVIQCHEGSGANFFCVLGFLGFLAGGTFSVAFLARGLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHQVQHNRQCEMLQRRCVSSGESLGSSL", "length": 878 }, "evidence": [ { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W842-1", "protein_name": "Vomeronasal 2, receptor 66", "gene_name": "Vmn2r66", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLISVFWFLKISSIFCHLSDPRCFWRIKDTKNHLGDKENNCFFSIYTKRGYVKNDYFSCNLDKQVTPKTIHLIFSVYLAIEEINKDYHILPNISLLVNIECDQRIYDKKSGLGLKSKEIIPNYYCRNQRRYLIVLTIPEWTVSTSLGPFLYISRIPELYCGNFHLLLNDNEQFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGAIVTNDDHGIQFLSELRGEMQKHIVCLSVAIIIQTEKIMALKEFHTHYNQIIMSSAKVVIVYGDKDSPIHFALIVWKSKGIWRIWVSVSQFDMITIIGDFLLYSSIGTFIFSHQQPEIPGFEQFIQTVHPSNYSSEHSLAKLWWTYFRCSLPPSNCKKLKNCPTTTVFKWLFMTPLGMAMSNTCYNLYNGVYAVALSLHEMILQQVDTWSMNAGKELEFDSWKLFYFLKTLQFVNPAGELVIMNQNLKQDTEYDIFFIMDFKKYYGLKIKIGRFSGHLPSGQQLLMSTEMIKWATGIDQILPSVCSMPCRPGLRKSPQEGKDICCFVCYPCPENEISNMTSNVIIYQNMDQCVKCPEDQYANEDQTLCLQKVVAVLDYRDPLGKALAGFALCFSVLTSVVICVFLKHRETPIVKANNQTLSYVLLISLIFCFMSSLLYIGHPTMVICILQQTTFAIVFTVAASTILAKTITVVLAFKATVPGRRMRWLLVSGAPKYIILICTMVQLILCGIWLRISPPFVDADIHMLHGQIIIVCNKGSVVAFYCVLGYMGSIALASFTVAFLARNLPHTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTTVAVEVFCILASSAGLLLCIFAPKCYLILLRPQTNSFYKFRRPHAKAENIS", "length": 858 }, "evidence": [ { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2WB67-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYFTFNCLFLLLQSLFTPVEMTRKSCYEFWNPSTYMKADIILGAFIPIFILLEGPKEIQQFIWIQPDIVLENILLQWKNYQYLMTLYFAIDEINKDTHLLPNVTLGFHIYNAFNFHPRTLEGPLMWLSGRNEFIPNYKCKTQYKALGIISGTRSEYSAGIGSLLERYKIPQVSFALLLQVNYGPFDSMLSDKDTFPSLYQMSPKDTALTQGVISVLLHFGWKWVGVIVSDDLKGMEFLSHLKAEMVSEDICVAFTKSLKTNWKVQYTSGVGLANLNHHPQVNVNILYGDIDDLLYFCLENKLLSSRRKVWIMAKLHLVYLESVFFKRKDLINFFTGSLLFSKKRNIPGFKNFLESLTPSYYPGEFYFYKFWIDKFDCAPPALLCGRNKPCPLNITLKNKEGENDIMIPSEASYSIWNTVYAVAHAIHNMFLRKTEIGSHEDKNHDRFLPWQLHPFLRKIQFTNTAGDPISFDEHKNHMEIYEIQNFMKYTKQHSYLVKVGEFVSKSPQDQSLFINESLIKWPNNFNQTPQSVCTQSCGPGFWKILQEERPVCCFSCVPCPEKHISNLTDQQKCIACLIQEYPNPERNHCLPKSATFLSFEDPLGMSLACMALGFSVSTAAVLGIFLKYQDSPIIKANNLTLSYILLISLLLCFLCSFLFIGHPNTVSCILQQITFALVFTLALSTVLAKTITVILAFRALKPGRTMRRLFVLGIYNAVIPFCVLIQLITSGIWLATSPPYIDTDSYSEHAHIIILCNNGSVTAFYCMLVYLGTLALGSFTVAFLARNLPDTFNEAKFLTFSMVVFCSVWVTFVPVYQSTKAKAMVAVEVFSILASSAGLLACIFFPKCYIILREPDKRNLKCFKNKTRIKK", "length": 871 }, "evidence": [ { "id": "MGI:3645314", "url": "https://alliancegenome.org/gene/MGI:3645314#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2WBA1-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r56", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLSCHWLSDPLAGMWLCTLLPVLFGCPSGSALSGARAWLLPRQSPHFDRPGDVIVGGSFSIFRFSNGTLSNFTAPPAGLQTSSVSMWGYRVAQSFVFAIEEINRSTHLLPNLTLGFSIRNSGDSAHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTSSHAVTQLIIHFQWSWVIILAHDDDFGQQASSLASQVLTPAGVCIEFYLYVPSHQSLGKIEETVRKMQKCTARVVLVFLSNYNFQLILYGLLAVPVSGQVWVSKDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCMWPYQNITVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHDMISYEHQDGKGTNSQDFQPWQLLHVLRKVHFKTPDGSEIMFDANGDLVTKFDIFQGQKTPDGVFHLVCVGLIDPQASSGNKMMVQKKMLKYQMKHAQVPTSVCSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCCIILLKPEKNTSSWLRQGHHV", "length": 865 }, "evidence": [ { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I6GK53-1", "protein_name": "Vomeronasal 2 receptor, 33", "gene_name": "Vom2r33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLCTFLFVLLGCLPGSALSEPRSWILPRQSPHFDRPGDVMVGGSFSIFCFSDGTLSNFTAPPTGLQASRVSMWGYRVAQSFVFAIEEINKSTQLLPNLTLGFSIQNSGDSVHGALYETMGFLTGQEEPIPNYTCCHGSPQAALVGDTRSSLSLPMARLLGLYKFSQISYSSSLPSLSDKIQFPSFLRTLPSDLTSCHAVTQLIIRFQWSWLIILSQDDDFGEQASSLATQQLSAAGVCIEFHLDVPSQHSLGKIEETVQKMQKCTARVVLVFLSNSNFQLILSGLLAASVSGQVWVSNDTLHIAMALSIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLHPSQIPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQVCSGNESLKNKPYPFPEVSKIDAAYTAVYSIAHALHDMVACEHQDGIDTNPQDFHPWQLLHVLKKVHFRTPDGSEIMFDANGDLVTKFDILQGQKTLNGVFHLVHVGMIDPQASSGNIMMIQLKEDLQVSSMNAEITVPTSICSERCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALMAILLAGLALLVLGVFLKHRDTPVVRVNNRTLSYFLLISLSLCSLCSLLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTVTVVLAFRVTKSGSRIQVCLSPGASTSVVLIASLIQVVLCGVWLATSPPFPERDMISEPQHIVIQCQEGSGATFFCVLGFLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHCAHQDRQCSLFH", "length": 864 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N5X2-1", "protein_name": "Olfactory receptor CW1 precursor", "gene_name": "olfcw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTPVLRAIHLVFFLFYPIQSNSEANCKLWKELDLTVVHKEGDVILAGMFPIHSKGIDQELNFRNQPDQRKCWGFNMRVFRWSQAMIFFIEEINRNPTLLPNITLGYRLYDTCGLIALSLRTALSVVSQPMKRSSSEMCSSPSIPIIIGDSGSTLSMAISRLLNLFHIPLVSYFASCACLSNKHQFPYFFRTIPSDVNQANALARLVKHFGWTWVGTVGADDAYGRTGIDLFTAAVTQLGVCVSYRIIIPKLPTQQQLQDIVRTIRDSSAHVLVAFAIEEDIKPVVDEIVLQNVTGKQWVASEAWVTSTLISTKENFPSLSGTIGFAIRRAEIPGLKHFLDSIQPLADPYNVFAREFWETQFQCTLNTSLPTSSTMDPVNYSHSCTGMERMQDTQSIFNDVSQLRVTYNMYKAVYTVAHALHNLLLCQREHRSALTQQCPDIHNLQPWQVIEVLRKVNYTNMFGDLIYFDENGDPVGSYDIVNWQKGGDDVPVQYITVGRFDSSLPKGQQLVLNQNKIVWHGGTNKVPVSVCSASCPPGYRKVRLEGQPVCCYDCMLCAEGSISNTTDQAECLLCPEDFWSNKHRNYCVPKEIEFLSYLEAFGMVLAAIAILGAVAAISVGVVFFRHRDTPLVRANNSELSFLLLISLTLCFICALTFLGQPSHWACPLRRISFGLTFALCLSCLLSKTLVVLIAFKSTLPGNNTARWFRPPQQRLGVFICSLLQGGVCIAWLTTASPYPVKNTWLYRDRIILECHLGSVVYFCCVLGYIGCLAAFCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSYGVLLCIFAPKCYIIIFMPEKNSKKYLMTQK", "length": 866 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PS22-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcx1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQIYATLLTLCLLLYIRVQCQSNNKYKCIYQGDDDTYSFYQGGDLVLGGIFPLHSSTIPQFFSFTTKPKLIQYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPEKGSGQSCEDTRKQPSPVIVGEASSGVSMAVLRTLGTFQIPLVSYFASCSCLSNKREFPAFMRTMPSDLFQIKALVKLVYYFKWTWLGVIGVDTDYARFAIQLFLKESEKYNICPAYVHIYPVALTQNTVEELVKILKSSSARVILNFSVDSYLYGVLKECRRQNVTNLQWIASEAWATSKVLWDDFGDLLKGTLGFAIRRADIPHLGSYLRSVSSSVAQTSPFFTEFWEETFHCRLNGSLNTHVHEEASYNWPACNGNETLDDVYTLYSDVSQLRVSYNVYKAVYLIAHALHDMSTCDPGKGPFKNGTCGSLYQILPWQLLYYMKRTNFTTLGEEVRFDKNGDPIASYDLMNWQRESDGSLQLVRVGIYDASFKDDKDLVIDESVIMWHRGDKAPESLCSKSCLPGSRKARQKGKPVCCFDCISCAEGEISNQTDSIDCLTCSKDTWPNQSQDQCIPKTLEFLSFQEPLGIILWVFSALGACAALAVLCVFVMYRTTPVIRGNNIELSFLLLLFLCACFLIGLTFLGKPTDWLCQIRYPAFGISFTLCISCILAKTVVVLMAFRATIPGNNVMKWFGPVKQRSSVILCTCVQALICIIWLTTKPPLASYNSKFLSATIIVECSVGSEVGFWCVLGYIGFLSSLCFFLAFLARKLPDNFNEAKFITFSMLIFFAVWITFIPVYVSSSGKYMVAVHVFAILASAFGLLMCIFAPKCYVVLLKPERNDKKSMMKK", "length": 866 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PU52-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWISLNIFLYLSLNCIFAASVVNPGTCQLQGHFKLNGMYQDGDFILGGLFEVHFFTLFPKLSFKSEPEPPYCEKFDMESFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCVMLGMAFRAAISLASGTEEYFSNLNCTGPPPVIGVVGDPGSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVRILSHFGWTWVGLIYSDDDYGIYASVSFQQEMQQFGSCISFSEILPHDNNPKDIQRIMEVIKASTASVVVVFSTSSYLMPLIDEVVLQNLTGRQWIASEAWATSPVFHTPRYLPFLGGTLGIAIRRGEILGLQEFLLHIHASNNPKDNMLKIFWENMFRCSFETRSKDTIGEQEKSICTGHEDLSTTKTPYTDVSGLRASYNVYKAVYALAHALHDLMECEEGRGPFDGNSCGNITNLKPWQLVHYLQKVNFKTGFGDHVSFDENGDALAIYDVLNWHPSSDGSIRLHTVGVVNEGAGTGKVLSLDESALYWNFQTKNPPRSVCSASCPPGTRQAMRKGLPICCFDCLPCGDGEISNATDSTECVTCPDEFWSNFDKNQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHLNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGTMKWFGAAQQRCTVLVLTALQVVICAVWLSNASPTPIKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKKAIIRRETKKR", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q146-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYQDGDFILGGLFEVHFFTVFPDLTFTTNPKSPYCEIFNMEGFQHAQTMAFAIEEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLTSGTEESFLNLNCSGPSPVIGIVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSNRKKYPSFFRTIPSDAFQVRAIVQVLKHFKWTWVGLLYSDDDYGVYAAQSFQQEMRQFGLCAAFSEFLPHDNNPRTIQHIMGVIQGSTAKAVVVFAPSSFLIPLMNEVVLQNMTGRQWIASEAWATSLESHIPSFQPFLRGTIGIAIRRGEIQRLHDFLLRIRPSNDPKNYMLRIFWENMFGCSFGKGDTEGEQVIKVCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHALHDLMECEEGKGPFSKNSCADKTNLKPWQVVHYLQNVNFTTGFGDYVSFDKNGDALAIYDVLNWQPSSDESIRIYTVGVVKEGTETGMVLTLDEDAIFWNFETRKPPRSVCSESCPPGTRRATRKGLPVCCFDCLPCGDGEISNTTNAVECFLCPDEFWSNQYNNHCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVIFVFALHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHVVFGISFVLCMSSILVKTMVVIAVFKSSRPEGKGAIKWFGAVQQRSTVVVLTVLQVLICAVWLSTASPTPYKNNQYIRSKIVYECAIGSVVGFSMLLSYIGFLAAASFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFVPAYVSSPGKYTVAVEIFAILASTFGLLIAIFAPKCYIILLHPERNTKNVIMGRETQNK", "length": 829 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q166-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWSPLIICLYLSYNFKSAASILMGSCQLQGHFGLNGMYQAGDVILGGLFEVHLLAVFPELSFRSAPEPPYCEQFDMASFQQAQTMVFAIDEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLVSGTEELFSNLNCTGSPPVIGIVGDSNSTPSIAISSVLGLFRVPIVSYFATCSCLSNRKQYPSFFRTIPSDAFQVRAMVNILKHFGWTWVGLIYSDDDYGNYAAQSFLQDIQIYGGCVAFTEILPLNNNRKYIEHVVGVIQASTARVVVVFSTSTYVLPLMDEVVLQNVTNRQWIASEAWATSPMFHTQRLLPFLGGTLGIAIRRGEIQGLHEFLLHLRPKNDQHNNMVRIFWEKMFGCRFNPGGKGDKQCSGQEDLSSIDTAYTDVKELRASYNVYKTVYALAHALHDLTECDEERGPFSENRCADITNLQPWQLVHYLQKVNFTTGFGDHVSFDKNGDVLAIYDVMNWHPSSDGSISVRTVGVVNEGAASGKVLTLDEDAIYWNFKIKKAPQSVCSESCPPGTRQATKKGLPVCCFDCLPCGDGEISNVTNAIECTVCPDEFWSNKDKDQCVPKEVEFLSYEDPLGISLTTACLLGTCFCALVMIIFCQHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGSMKWFGTTQQRCTVLILTALQVVICIVWLSNSSPAPHKNSQHISSKIVYECAIGSLAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVTSPGKYAVAVEIFAILASSFGLLGAIFAPKCYIILLHPEKNTKKAIMGRQITK", "length": 860 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q1C5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNAHLLFTVKMLCIARLCIAVCGVDLGTCILQGDAQPPALSEDGDFIVGGAFTIHYYVRTEKYTYTRRPQPLECSGSMDFRELRFARALQFAIQEINNSSDLLPGIFLGYHIYDSCGSVPMAIKVALQLANGLDPKYNDTDSCAKSAAVLALVGDSASTPAISISRIFGPFEIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEKEGICVEYSEAYYRTYPLSKLKRVADVIRRSTARVIVAFVAAGDMRFLLEELSKEPLPPMQWIGSEAWVSDPQMLRFNLSIGTMGVAVPRSLIPGFRKFLLDLSPYKVLKFPLLTEFWESSFSCSLQQQTDPSTGMPACDGTEDLGRLKNPYTDTSQLRVSNMVYKATYAIAHALHGIVCNETQCSKNIKVKPRQVFDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPEGQEFSLNKAIIWYDGSEKVPVSVCSENCPPGTRKAVKKGRPVCCYDCIPCGEGEISNKTDSPDCDKCPPDYWPSTEKDKCLPKPVEFLSWDEILGIILAVLSVSGSLLALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWVVLGYIGLLASLCFVLAFLARKLPDNFNEAKFITFSMLIFSAVWITFIPAYVSSPGKFTVAVEIFAILASSFSLILCIFAPKFFIILFRPEENTKKHLMGKVQSKSY", "length": 856 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RHU5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCCYICVTLIASTGTCQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMTSFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTSRQWIASEAWVTAAVFRTPYFQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTTNTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEGSIKLHNIGVVNEVATGMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTSRAMRKGFPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDRCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AUZ8-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcv3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHSLETMTILLLWLLVYHLSVLNPAQASKCLLQNEFEPGLMANGDFVIGGIFPLHYNQEMPDLNFTYKPGPVKCNGFDTRAFRWAITMKLAVEEINKRVDLLPNYTLGYKIFDSCAYPLTGQRSAVAVLNGPNELESPLCADAAPLLAVIGESGSAQSIVVSRILQPFGIPMISYFSSCACLSDRREFPTFFRVIPSDAYQVKAIAKLLRHFNWTWIGVIRGDHEYGRFALQGLLKELEGTGICVAYQKMIPLLYDRQKALEIIHVMSHSTARVVVVFSAEGELTPFLRDYMEQNVTGIQWIASEAWVTSSVFAGSEFDPFLGGTIGFGIRQGQIPRLKEYLTTVNPERYPTNPLVYELWGALYGCSPSWSNLSSHLPSCTGKETVRLQYSAYLNTSSPRISYNVYKAAYAIAYSLHNLIYCTPGKGPFSNSTCANAPHIYPWQLQQYLQEVSFTISGEKVNFDMKGDSIPSYDLINWQRGSAGNIEFINVGMFDGALESGQELVIKEEAIMWPGHQTEVLVSVCSNSCAPGFRKAVRRGQPLCCFDCVPCDSGKISNETDSLDCIACSEDYWSNADGTVCIPKVVEFLSHDAMGLTLTVIAVAGACLTLAVFSVFLYYKNTPVVRINNSELSFFILLSLTLCFLCALIFIGEPTSWSCMLRHTAFSITFSLCISCILGKTLVVLAAFTATRPGNNLMKWLGPTQQRIIIFCCTLIQVLICTVWLVASPPFPYRNTKYQQSKIILDCSVGSDLAFWCVLGYIGLLACVCFFLAFLARKLPGNFNEAKYITFSMIIFCAVWLAFVPAYVSSPGKFTTAVEIFAILASSFGLLLCLFTPKVYIILVKPEKNTKQHLMGKDK", "length": 859 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AV03-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYNNVLLIVTLQCIITRLYVVYGNRLGSCILQGDPQPPVLFDEGDFIIGGAFSIHYYLRTEKHTYTMRPQSLECSGSMDFRELRFARVLQFAIQEINNSSDLLPGITLGYRIYDSCGSVPMAVKLSFQLANGLDLIFNDNDSCSKSAAVAALVGESGSTPSISISRLYGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEEEGICVEYSEAYYRTQPRSKLMRVADVIRRSTARVIVAFMASGDMRLLLEELSQQPLPPMQWIGSEAWFTDPEMLRFNMCIGGVGFAIPRSVIPGFRTFLLDLSPQRAMKFPLLTEFWESSFSCSLKQQTGPSTGMPACDGTEDLGRLKNPYTDTSQLRISNMVYKATYAIAHALHGIICNEKKCNKNIKIEPREVLDKLKQVKFSKNNYSVSFDAYGDPVAVYELVNWQLQKDGSIDFVTVGKYDSSQPKGKEFSLSRAIIWYDGTEEVPVSVCSESCPPGTRKAVQKGRPVCCYDCINCADGEISNDTDCLDCHECLSDYWPNNEKNKCLRKPVEFLSWDEILGIILAAFSVAGSLVALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPSQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFGLILCIFAPKFFIIIFRPERNTKKHIMGKVPSKAL", "length": 856 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B2Z8-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcg8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLFLYSVLSLYHLNTKAENTLCQMIGNPKYPLLSKDGDITIGALFVIHSEVSLPSFAFTQKPNLLSCSSLNIKDFRLAQTMIFAIEEINKNTNLLPNISVGYQIYDTCGSRFHSMSATMALMNGPKNSEGYTCNEQSSVHAIVGETESSNTIILSRTTGPFKIPVISPTATCECLSNRKEFPSFFRTIASDYHQSRALAYIVKHFGWTWVGAVNSDNDYGNNGMATFQKTAKEVQICVEYSVKFIRTETEKIRNVVNVIKKGTAKVIVAFLTGFEMKSLLEQLSSQNITGLQMIGVEAWITSKTLITSKSFHVLGGSLGFAVRKIQIEGFADYVMKAFWDTAFQSFSNADLNYSQYQDLLLVKNYNEDVLEQRFVSYVYKAVYALAHSLHSLLRCTEQGGCGKALTIQPHQLVEALRKVNFTVKMGDQVWFDSTGGVIAQYDVVNWQQNSDGSVQFQSVGYYDASLSPDQRFMLNTEKIVWAGGQLEKPRSVCSESCPPGTRKASQKGRPVCCHDCIPCADGEISNETDSNNCKQCPGEYWSNANKNKCVTKAVEFLSFTEVMGIILVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSIPFIGRPTQWSCMLRHTAFGITFVLCISCILGKTIVVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTLIQGLICVIWLTKSPPFPYKNMKYFQEQIILECSVGSTIGFWAVLGYIGLLAVLCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKLTVAVEIFAILASSFGLLFCIFAPKCYIILLQPEQNTKQQMMAKTPSKI", "length": 832 }, "evidence": [ { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PAH3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTKKSELLLLMVLVTHGICVPNLAQVCRLLGQPALPLLSEERNINIGAIFSLHKSALLKSHNFTSKPKQTTCGGLNLREFKFVQTLIFAIEEINNSSLLPGASLGYKIYDSCGSVAQAIFSGMALMNGYEETLSDTSCSTPPAVHAIVGESNSSPTIGLASVVGPFSLPLVSHFATCSCLSNRKRFRTFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGIATFEEAAKQEGICIEYSEAVFKTDPEVQFLKTIEVIKKATTKVVVAFMAFGDFVLLLKVMAQQNITGIQWIGSESWITSRNLAETKEYHFLSGAVGFAIANSKPVGLREFLMNVHPDKELNNELLKEFWETVFLCSFRNSSSGGCTGSEKLSELQNEYTDFSELRIENKVYTAVYAVAHSLHNVLKGFKFFTNSSKKQLPTPQKVLEYLRDVNFTVNTNENIFFDASGDPVARYDLVNWQPTKDGSLQFKLVGIYDSSLPSEQRLQINQESMLWAGNSGQLPVSVCSESCPPGTRKAVQKGRPICCYDCIPCAEGEISNYTDSSDCFPCGLEYWSNESKDRCVLKVIEFLSYTEIMGVGLCIFSFIGVLLTATVSFLFYFYKETPIVRANNSELSFLLLFSLTLCFLCSLTFIGRPTDWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLIQVIICVLWLTMSPPFPFLNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFFARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSAPGKYTVAVQLFAILASSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKS", "length": 849 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PFV7-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcg9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLYLCTLLLFFKLKVSVGNASCKIMGEPKYPLLFKDGDVTIGALFPVHSIETAPSFEFTQKPQLLSCSSVNLRDFRLAQILIFAIEEINRSESLLPKLSLGYKIYDTCSSKLSSMSATMALMNSFEFAGRDKCNGQTSVHAIIGETESSATVILTRTTGPFKIPVISHAASCECLSSRKEYPSFFRTISSDYHQGRALAYIVKHLGWSWVGAVNSDNDYGNYGMAIFLNTAHKEGICVEYSEKFYRTEPEKLKKVVDTIKKSTAKVIVAFISFLEMRLLVEQLSAENITGLQIVGVEGWTTSKSLITPKTLNVLRGSLGFAMRKIYIEGFAEYVLKPFWDTAFPCIPNQRNDSWVILNCSRYQDLLVLKNYIEDVPEHRFSINVYNAVYAVAHALHSLFKCKEQEGCEKDLLTQPQQVVDALKKVNFTVKMGDRVWFDSTGATLAQYEVVNWQQNSDGSVNFKKVGYYDASLPPDQRFVLNIKEILWAGGNLKKPRSVCSESCPPGTRKAAQKGRPICCYDCIPCADGEISNDTDSNNCKQCQGEYWSNADKNKCVQKSVEFLSFTEVMGIVLVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTQWSCMLRHTAFGITFVLCISCVLGKTLLVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTFIQVLICVLWLSISPPFPHKNMKYYEEKIILECSLGSTIGFWAILGYIGLLAALCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSISLLLCIFAPKCYIILLKPEQNTKQYMLGKTTSKFY", "length": 839 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPM0-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcg12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVFFCTLLIFFQLYAKAEKPICIMMGDPKYPLLSKEGDISIGAVFPVHSIETLPLFKFTQKPQLLSCSSVSIRDFRMAQIMAFAIEEINRNESLLPNVSLGYQIYDTCGSGLSLMGANMALMNVQEFASRGSCNGQSPVHAIIGETESSNTVILSRTTGPFKIPVISPSASCECLSNRKEYPYFFRTIASDYHQSRALAYIIKYFGWSWVGAVNSDNDYGNHGMAIFLSTAEKEGVCVEYSVKFQRTEPEKLKKVVDTIKKGTSKVIVAFLTEFEMKNLLEYLIIQNVTGLQVIGVEAWITANSMIKPNSFHVLGGSLGFAVKKLNIEGFEDYVTKAFWETAFPCSQTSQKENSQYKLICNIYRDLLVLKNDNKDVPEQRYASNVYKAVYAVAHSLHNILKCRENGACETDMKIQPQQVVEALRKVNFTIKMGDCVWFDSTGAVVAQYEVVNWQPDYNGSIQFKPVGYYDASLPPNQRFVINTENIIWAGGQLKKPRSVCSENCPPGTRKAVQKGRPVCCYDCIPCAEGEISNETDSNNCKQCPGEYWSNAEKNKCVLKAVEFLSFKELMGIVLVFFSLLGAGLTTLVAILFYSKKDTPIVKANNSELSFLLLFSLMLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSDVMKWFGPIQQRLSVLVITIVQVLICVLWLAVSPPLPYKNTKYFKEKIILECSLGSTIGFSAALGYIGLLAILCFILAFLARTLPDKFNEAKFITFSMIIFCAVWITFIPSYLSSPGKLTVAVEIFAILASSFGLLFCIFLPKCYIIMCKPEQNTKLHIIGKLNK", "length": 837 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2U8-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLCEMWITLNICLYMYFNHISGVFTSESCQLQGCFKLNGMYQDGEFIIGGLFEVQNLKVFPELSFTNEPELPQCEEFYMASFQQALTMVFAINEINSNSKLLPNITLGYQIYDNCLRLGVAFRAAMSLVSGTEESSNLSCTGPPPVIGIVGDPGSTQSITISSVLGLYRVPMVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLLYSNDDYGIYAAQSFQQEMQILGGCVAFSEMLPYDNNGRDIQRIAGVIQKSTAKVVVAFSTDLASLMDELLLQNVTGKQWIASEAWTTTPVLQTPQYLPLLGGTLGIAIRRGQIQGLYEFLKNLRPDKNPKNSTIRIFWETMFGCKFEVGGKKVDEQQERGRNKCSGQEDLNNSETAYTDVSELRASYNVYKAVYALAHALHDLVKCEEGKGPFTGNSCADISNLKPWQLVHYIQNVKFTTGFGDHVSFDENGDALAIYDVMNWHPRSDGSIIVHVVGVYEEAILGKVLTLDEDALFWNFETKKPPDSVCSESCPPGTRRARKKGLPVCCFDCLPCGDGEISNTTDSPECFICPEDFWSSPENDRCVPKEMEFLSYDDPLGISLTTASLLGTCFCVLVLVIFAYHHNTPVVRANNSELSFLLLVSLKFCFLCVLLFIGRPRLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKTSRPEGKTSIKWFGSAQQRGTVIALTSAQVAICTVWLSSASPTPHKNNQYIHSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFMARKLPDNFNEAKFITFSMLIFCAVWIAFVPAYASSPGKYAVAVEIFAILASSFGLLAAIFAPKCYIIILHPERNTKKAIMGRSTQNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2V5-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcx2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALLCATLLMVWFLMYLSVQSQYNSKVRCVFQGDDDTNTFYQGGDVVLGGLFPLHFSPISSLSSYKTKPTPTTYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPDKDSGQSCEDTRKQPSPVVVGEASSGISMAVLRSLGCFKIPLVSYFASCSCLSNKKEFPAFMRTMPSDLFQIKALAKLVHYFQWTWVGVIGVDTDYARFAIQLFLKESQQLNICLAYVQLYPVALNQDSAEELVRMLKSSSATVIISFSVDSYLYGILKECRRQNVTHLQWIASEAWATSKSLWEEFGDLLKGTLGFAIHRADIPHLGSYLKEIRPQTSHFLSEFWEETFRCRLNGSLNTHAHGEQAQNWPACNGSESLDDVYTTYSDVSQLRVSYNVYKAVYLIAHALHDMSTCVPGKGPFQNGTCGSLFQIQPWQLLYYMKQTNFTTLGEEIRFDENGDPIASYDLMNWQRGSDSSLQLVRVGFYDASLEDDKDLVIDESLIMWHRAEKAPESLCSKSCLPGSRKARQKGKPVCCFDCISCAEGEISNHTDSIECLTCSEDTWPNQSQDQCIPKTLEFLSFQEPLGIILWVFSAFGACAALAVLCVFVMYRKTPVVRGNNIELSFLLLLFLCACFLIGLTFLGKPTDWLCQIRYPAFGISFTLCISCILAKTVVVLMAFRATIPGNNVMKWFGPVKQRSSVILCTCVQALICIIWLTTKPPLASYNSKFMSETIIVECSVGSEIGFWCVLGYVGLLACLCFLMAFLARKLPDNFNEAKFITFSMLIFFAVWITFIPVYLSSSGKYMVAVHVFAILASAFGLLLCIFFPKCYIVLLKPEKNDKKHIMKK", "length": 863 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T5D2-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCYYICVTLMASTGICQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMESFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLHNLTSRQWIASEAWVTAAVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTANTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEESIKLHNIGVVNEVATEMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTRRAMRKGLPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDQCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSLAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6G6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAILLFCLFLSCNFICVTLMVSSGTCQKQGHFTLNGMHQDGDFVIGGLFEIQSYVKVYPEISFRTQPKLPNCDLFYMTSFQQALTMVFAISEINNNPNLLPNITLGYQIYDNCLRLGVAFRAATALISGTEETISDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRLPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAMVQTMRHFGWTWVGLIYSNNDYGIYAAQSFHKEMQLFGHCVAFSEILPQDNNPRVIDHIIGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTGRQWIASEAWVTSTVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETEDKETFGQQIKKVCTGQEDLSITNTPYTDVSGLRAPYNVYKAVYALAHALHDLMQCKEKRGPLSEKNCADITDLKPWQLLSYLKKVNFTTGFGDPVSFDNNGDALAIYDVLNWQPSSEGSIKLHSIGVVNDEVATGMVLRLNKDEIYWNFEAQKAPRSVCSESCPPGTRKAMRKGFPVCCFDCLTCGDGEISNTTDAIKCTVCPDEFWSNFNKDQCVPKEIEFLSYEDPLGISLTTASLLGTCFCALVMIIFAFHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFNSSRPEGKGAMQWFGAAQQRCTVLVLTVLQVVICAVWLSTSSPTPHKNNQYVRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRETKKY", "length": 869 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3645314", "url": "https://alliancegenome.org/gene/MGI:3645314#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6Z6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcq17", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLYLSLCLCFKHIYADSIHRLRSCQLQGRFKLNGMYQDGDFILGGLFHVHFFTVFPELSFRMEPQQPYCEKFNMEGLQHAQTMAFAINEINKNPTLLPNITLGYHLYDNCVMLRMAFRAAMSLASGTEDSYSNLNCTGPPPVIGIVGDASSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKHFKWTWVGLLYSGDDYGVYAAQMFHKEMQLSGHCVAFSEILPNDHNPKDIQRIIRVIQGSTARVVVVFALSSFLIPLMDEVVLQNMTGCQWIASEAWATSLEYHTPRFLPFLGGTLGIAIRRGEIEGLHEFLLRIRPSNDTSQNIVRIFWENLFGCRFETGGLKTGREQEKMECTGQEDLSTTNTPYTDVSGLRASYNVYKAVYALAHGLHDLMQCEEGRGPFIGNSCADITSLKPWQLVHYLQNVNFTTGFGDHVTFDKNGDALAIYDVLNWQPSSDGSITVHKIGVVYEGATTGMMLTLDADAIYWNFETKKPPLSVCSESCPPGTRQATRKGLPLCCFDCLPCGDGEFSNTRDAVECMMCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGAMKWFGASQQRCTVLVLTALQVVICAVWLSTASPTPHKNNHYFRSIIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFALLLAIFAPKCYIILLHPERNTKNAIMGRETQNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TDV0-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfck1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRISLGWVVCLVKEMHVNLLLILTLLCIRRLFPAVCGVHLGTCILQGDPQPPSLFSKGDFVIGGTFTIHYYLRTEKRTYTVRPQPLMCSGSMDFRELRFARVLQFAIQEINNSSNLLPGITLGYHIYDSCASVPMVIKVAVQLANGLQLAFNDTDSCAQSSEVLALVGESGSTAAITTSRLFGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEVEGICVEYSEAYYRTQTRNKLQRVADVIRRSTARVIVAFMAAGDMRFLLEELSQQPPPPMQWIGSEAWVTDPQMLRFNLSIGAVGFAIPRSVIPGFRKFLLDLSSEQALKIPVLKEFWESSFGCSLKQHTGYFSGMPACDGTEDLGTLKNPYTDTSQLRISNMVYKATYAIAHALHGIVCNGKLCDKNIKVEPRKVSDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPKGQEFSLNRAIIWYDGTEKVPVSVCSESCPPGTRKAVKKGRPVCCYDCINCADGEINNETDSLDCHKCQPDYWPNAEKIKCLPKPVEFLSWDEILGNTLAAFSIAGSLVALSMALVFYKNRVSPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFSLILLIFAPKCFVIVFRPEENTKRHLLGKVPPKAL", "length": 870 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUY1-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWVILHIYFFISCNYMSVALMASSGTCQLQGHFTLNGMYQNGDFLIGGLFEIQYLKAFPGLSFRTEPKLPHCENFYMTSFQQAITMVFAINEINNNPNLLPNITLGYQMYDNCLRLGVAFRAATALISGTEETLSDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMIQILRHFEWTWVGLLYSDDDYGINAALSFHHDVQQFGGCVAFSEILPNDNNQMAVQHIVRVIQNSTAKVVVVFSTSSYLLPVIDEMLLKNITGRQWIASEAWSTSPVLLNPRLRYVLGGTLGIAIRRGEIEGLDNFLLRLRPDNFSQNSMMRIFWENMFECNFDTIGGLRTKLCSGQEDLRSKFTPYTDVSELRASYNVYKAVYALAHALHDLMHCEEGRGPFSENRCVDISNLKPWQLVHYLQRVKFTTGFGDHVSFDKNGDALAIYDVLNWQLSSEESVTVRRIGVVDEGVTTGKVFTLDENAIYWNFETNKPPRSVCSESCPPGTRQATRKGLPVCCFDCLPCGDGEISNTTDTTECIACPNDFWSNPEKDQCIPKEVEFLSYEDPLGISLTTAAMLGTFICALVMTIFAHYRNTPVVRSNNSELSFLLLLSLKLSFLCVLLFIGQPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKNAMKWFGAAQQRGTVLILTALQVLICAVWLSTASPTPHKNSRYIRSIIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDSFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIIILHPERNTKKAIMGKGTKNK", "length": 863 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UVL1-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLTWHRLFIKATPSKVFIINNIHRGELKRNVEMWIIAKICLYLSFSCISVASIFRSGPCQLQGQFRLNGMFQEGDLILGGLFEVHFLTVFPEQSFRTEPEPPYCEQFDMASFQQAQTMVFAIDEINRNPNLLPNITLGYYLYDNCVKLSVAFRAAMALVSGTEESFSSLNCTGPPPVIAIVGDPGSTHSIAISSILGLFRVPMVSYFATCSCLSDRKTYPSFFRTIPSDAFQVRAMVQILKRFGWTWVGLLYSDDDYGIYAAQSFQKEMQLFGACVGFSEMLPRDNNHEDIQSIVEVIQTSTARVVVVFSTEAYLLPLMDEVALKNVTGRQWIASEAWATSPVFHTQHLLPFLGGTLGIAIRRGEIQGLKEFLYYLHPDSNTRNNIVRIFWENIFGCSFEIGGRERKVCTGQEDLKSTNTAYTDVSGLRASYNAYKAVYALAHALHDLMQCEDGRGPFSGNKCADQINLQPWQVVHYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWQPSSDGAISVSTVGVVNEGASMKMVLTLKENSIFWNFKNRKPPQSVCSESCPPGTRQVRRKGLPVCCFDCLPCADGEISNTTDAIECKICPDELWPNPNKDQCVPKEEDFLSFEDPLGISLTTASLLGTCFCALVMVIFSHHRNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPKLWTCQLRHAAFGISFVLCVSSILVKTMVVIAVFKSSRPESKSAMKWFGVAQQRGTVMALTTLQIVICTVWLSMASPKPYKNSLYISSKVVYECDIGSVVGFSLLLGYIGLLAAVSFLFAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYMILFHPERNTKKSIMGRATQIK", "length": 894 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V5L1A2-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSVSMWGYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFSQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSHQSLGKIEETVQKMQKCTSKVVLVFLSNSNFQLILHGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVPSSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPSWLKQGHHI", "length": 845 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AB13A3P1-1", "protein_name": "Olfactory receptor CG7", "gene_name": "olfcg7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSANSLFMVSLTFRMILYFYTILFLRCFQAKTENAFCQIIGEAKYPLLSKDGDVTIGGIFAIHSKETLPSFEFQQKPQPLLCSSVNLRDFRLAQIMIFAIEEINKSENLLPNVSIGYRIFDTCGSRLSSMSATMGLMNELKFAAGETCNGQSPIHAIIGETESSATVILSRTTGPFKIPVISHSASCECLSNRNDYPSFFRTISSDYHQGRALAYIVKYLGWSWVGAVNSDNDYGNYGMAIFLETAQKEGICVEYSVKFYRTETEKLKRVVDTIKKSTAKVIVAFVSFIEMGLLIEQLSIQNITGFQIIGVEGWITSKNYITTNSFHSMGGSLGLALRKIHLEGFLDYVTKSFWSTAFPCSQTEGILPTVGCSKYKDLLPLKNYTEDVPEHRYSSHVYKAIYAVAHSLHSLLKCKEGEDCEKGHATQPQQVVEALKKVNFTVKFGDRVWFDRTGATVAHYEVVNWQQDTDGSFQFKQVGYYDASLPPDQRFVLNIESIIWPGGNLEKPRSVCSESCSPGTRKAAQKGRPVCCYDCVPCADGEISNETDSVNCKQCPREYWSNGEKNKCVLKAIEFLSFTEIMGIVLVCFSLFGVGLTAVVAILFWSKMDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMVFKATLPGSNVMKWFGPTQQRLSVLAFTFIQVLICVLWLTISPPFPNKNMTYYKEKIIIECSLGSTISFWAVLGYIGLLAVLCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSFGLLLCIFAPKCYIIICKPEQNTKQHVMGKTSLKVQ", "length": 851 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TCB3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNFGAGLRTGSRNGNEKWKRMTFCRSSAFCHMFSSTLYLISSMARHAVVLRAGACQLQGRFRLNGMYQDGDVILGGLFEAHFFTLFPELTFRTEPAPPYCEIFNMESFQYAQTMAFAINEINRNPSLLPNISLGYHLYDNCVMLGMALRAAMSLVSGIEESFLNLNCTGPPPIIGVVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMIQLISHFGWTWIGLLYSDDDYGTYAAQSFHQEMQLFGFCIAFSEPLRYDSNPRDIQRLMEVIQASTSTVVVVFSPSTLVIPLMNEVVLQNMTGRQWIASESWATSPVFYTPRFLPFLGGTLGIAIRRGEIEGLREFLLQLRPKNDPRNNMLKIFWENMFGCSFETGPHVKNVCTGQEDLSTTNTPYTDVSELRAANNVYKAVYALAHALHDLMKCEEGKGPFSKNSCAEISNLKPWQLVHYLQKVNFSTRFGDHVSFNKNGDALAIYDVMNWQPGSDRSIRIHTVGVVSEELEKGLMLTLDEDAIYWNFETKKPPQSVCSESCPRGSRRATRKGHPVCCFDCLPCRDGEISNTTDATKCTVCPDDFWSNLYKDQCIPKEVEFLSYNDPLGISLTTASLLGTCFCAFVMVIFVHHHNTPIVRANNSELSFLLLFSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKMAMKWFGAAQQRCTILALTAIQVVICVVWLSTASPTPHKNNLYIRSIIVYECTIGSVTGFSMLLGYIGLLAAVSFLIAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYSVAVEIFAILASSFGLLVSIFAPKCYIILLHPERNNKKAIMGRETH", "length": 888 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0T300-1", "protein_name": "Olfactory receptor CD2 precursor", "gene_name": "olfcd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANTLSLLLLLLLLHGHFLPATVQICDLVGQSALPVLSAERDINIGAIFSIHRNALLRLYPFTSKPEPTTCVRLNLREFKFAQTFIFAIEEINNNTQLLPGVTLGYKIYDACNAISPTLVSGMALINGYENTLSDTSCSQPPAVQAIVGESSSSPTTALAALVGPFNIPVISHFATCACLSNRKRYPSFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGITAFEDAAKQEGICIEYSEAILRTDPQEQFRKTVEVIKKGTSKVVVAFISFGDFAPLVKVIAENNITGLQWVGSESWITSRNLAETKEYSFLSGAVGFAIVNAKLVGLKEFLVNVHPDQEPKNKLLKEFWETAFQCSFSNSDSALCTGSEKLGELKNEYTDVSELRIEHKAYAAVYAVAHTLHNVFKDVKAPNNSKRELPTPQKVLQYMRNLSFTIKTGENIFFDASGDPVARYDLVNWQTAEDGSLQFKHVGIYDSSLPSKQRLQVNQEIMLWAGKSGLLPLSVCTESCLPGTRKAVQKGRPVCCYDCIPCAEGEISNSTDSSDCFSCDLEYWSNEKKDRCILKVVEFLSYAEIMGIILCIVSFIGLLLTVMVTCLFYLHKETPIVRANNSELSFLLLFSLSLCFLCSLTFIGRPTQWSCMLRHTAFGITFILCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLVQVIVCLLWLTLSPPYPYMNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSSPGKYTVAVEIFAILVSSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKL", "length": 848 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0T301-1", "protein_name": "Olfactory receptor CQ19 precursor", "gene_name": "olfcq19", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWVILNISIYLIFNFIMSASILGSNTCQLQGHFRLNEMYHDGDVILGGLFEVDFLTVFPDLDFKTEPEPPYCVQFDMESFQQAQTMAFAIDEINKNPNLLPNITLGYHLFDNCVMLGMAFRAAISMASGTEEFFNNINCTGPPPVIGIVGDSSSTVSIAISSILGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKYFRWTWVGLIYSDDDYGVYAAQSFQQEMQLFGGCVAFSEVLPHDNNLEDIKHITKMIQASTARVIVVFSTPSFLIPLIDELVLQNMTDRQWIASEAWATSFVHHSPRLLPFLKGTLGIAIRRGEIQGLYEFLLRLQPTNDPKNNMIRIFWEIMFGCNFETGGKKNSGDQVINICTGQEDLRTTKTPYTEVSELRASYNVYKAVYALAHALNDLMQCEDGRGPFSVNSCADITNLKPWQLVHYLQNVNFTTDFGDHVSFDKNGDALAIYDVLNWQPSSDGSIRAQTVGVVNEEVATGMVLTLDEDALYWNFESKKPPSSVCSESCAPGTRLATIKGLPVCCFDCLPCGDGEISNITGAVECTMCPDEFWSNLDKDQCIPKEVEFLSYEDPLGISLTTASLLGTCFCVLVMFVFAVHRNTPIVRANNSELSFLLLLSLKMCFLCALLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPESKGAMKWFGAVQQRCTVLVLTAIQVVICAVWLSTASPAPHKNNQYIRSKIVYECAIGSVAGFSMLLAYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIILLHPERNTKKAIMGKEAQNT", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z4N8-1", "protein_name": "Vomeronasal 2, receptor 72", "gene_name": "Vmn2r72", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKISFIFCHLSDPKCFWRIKDTENKIGDIETYCSFSISTKPGYVKNDYFILEIIFSTSVFRVTPKTNHLIFSVYLALEEINMNFHILPNISLVVNVECLRQKYDEKTGLALQSKEFIPNYSCTNERRYLIIFTAPIWAVTTRLGPLMFMYSIPELYCGHFHLSLSDNEQFPHLYQISPKDTSLPLAMVSLMVHFKWNWIGAMITNDDHGIQFLSKLRGEMQKHMVCLSFVFAILTEHSMVRKEFHKNFNLIVRSSAKVVIVYGDYASPIDLVLHWFKSKGLFRIWVSVSQFDIITNLGDFMLYSSSGTFIFSHQKPEISGFQKFIKTVYPSNYSSEFSFAKLWWTYFRCSLPPSNCKTLKNCPTKTVFKWLFRTPLGMAMSDTCYNSYNAIHAVAHSLHEMLLQQVDTWSNNDGKDLEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTEYDIFYIMDFQKHYGFKMKIGRFSGHLPSRQQLYMSKEMMEWATDVDQILPSACNIPCKPGFRKSPEEEMDICCFVCNPCPENEISNMTNMDQCVKCREDQYANEDHTLFLQKVVSILDYREPLGKALAGFALCFSVLTSGIFCVFLKHRETPIVKANNQTLSYVLLISLIFCFICSLLYIGHPTTVICILQQTTFAIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLVSGAPKYIILICTMIQLILCGIWLGTSPPYVDADVHMVHGHIIIVCNKGSVIAFYCVLGYMGSFALTSFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYQSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYIILLRPHINSFRNFRKPHAKTENIS", "length": 856 }, "evidence": [ { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z7M3-1", "protein_name": "Vomeronasal 2, receptor 73", "gene_name": "Vmn2r73", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLIFIFWFLKISYIFCHLSNPRCFWRIKDTKDKLGDKETYCFFSISAKHGYIRNDYFSWNLDKHVTPKTNHLIFSVYLALEEINKNSHILPNISLVVNIECVLLKYGEKTGLGLKHEEFIPNYYCANERRYLIVLTAPIWAVSTKLGPFLFMSRIPELYCGHFHLPLSDNEQFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGVIITNDNHGIQFLSELRGETQKQIVCLSVVIIIQTDDITAYKEYHMNYNKIVMSSAKVVIVYGDHNSPIKFVLFLWKSQGIFRIWVSVSQFDMITPLGDFMLYSASGTLIFSHQQSELSGFEKFIKTVKPSNYSSEFSFAKLWWTYFRCSSLPPSNCKKLKNCPTKTVFRWLFMTPLGMAMSDTCYNLYNAIYAVAHSLHEMLLQQVDTWSENAGKELEFDSWKMFSILKTMQFVNPAGDLVNMNQNLKQEREYDIFYIMDFQKDYGLKMKIGKFSGHLPSHQQLYMSKEMIEWATDMDQILPSICSMPCRPGLRKSPQEGKDICCFVCNPCPENEISNMTNMDQCVKCPEDQYANEDHTLCLQKIVAILDYRDPLGKALAGFALCFCVITSGVLCIFLKHRETPIVKANNQTLSYVLLISLIFCFICSLLYIGHPTIVICVLQQSTFAISFTVAASTILAKTITVVLAFKVTVPGRMRWLLVAGAPKYIILICTMIQLILCGVWLGTSPPFVDADLHMVHGHIIIVCNKGSVIAFYFVLGYMGSIALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWVTFIPVYYSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYNILLRPGKNSSHMFKKLHAKTENII", "length": 851 }, "evidence": [ { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZEQ5-1", "protein_name": "Vomeronasal 2 receptor, pseudogene 67", "gene_name": "Vom2r-ps67", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKIFFLIVVFLLLKLSFLFCHLSDPRCFWRIKDKENYQGDKDIDCFFSIYTEHGYVKNDYFSGNLDKQVTRKTIHLISSVYFAIEEINRNIHILPNISLLVKTECNLFADNVDTVRSLKKKEIIPNYYCKHQRRYLIVLTGPPWLTSYKLGPFLFFSRTPELYCGYFHFRADQEQFPHLYQMSPKDTSLPLAMVSLAVHFRWNWVGVIITDDDQGIQFLSELRTGVEKSTVCVAFVTITTDDRMLYFKMIHKYYHQIITSSAKVVIVYGDKESLIQYNFMLWKSKNVQRLWVSVSQFDMITMIGEFMLHSLHGSIIFSHQHSEMSGFKKFIQTVNPSNYSNDISFAKLWWTFFKCSLPPPNCTTLKNCPSKILSKWFFVSPLGMSMSDICYNLYNAVYAVAHSLHEMLLQHVEIYSDNDGKVVEFNSWKIFSLLKTIQFVNPAGDLVNMNQNIKLGTEYDIFYVMDFRKQEGLKMKIGRFSGHFPNDQQLFMSDEMIEWATDIKQTLVSICSVPCRPGLRKYFQEGKAVCCFDCYPCPENEISNMTDMDDCVKCPEDKYANTDKTNCLKKVVTFLDYEDPLGMTLAGLALWFSALTAIVLCVFLKHRDNPIVKANNETLSYVLLISLIFCFICSLLYIGHPSMARCILQQTTFAIVFSVAASTVLAKTITVVLAFKITLPGRRLRWLLLSGAPNYIIPICTMIQMILCGIWLGISPPFVDADLHMVHGHIIIVCNKGSVIAFYSVLGYMGSLALSSFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFLPVYHSTKGKAMVVVEVFCILTSSAGLLLCIFVPKCYIILLRPQINSFHNFSKMRAKATSIN", "length": 853 }, "evidence": [ { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AB78-1", "protein_name": "Vomeronasal 2 receptor, 43", "gene_name": "Vom2r43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSLILVLLFLKASLLFCTLNDPKCFLRIKDKKNVDGDKEVDCFFSIYAKHGHVKNDFFSGNLDKQLTTKNIHLILSLYFSIEEINSTPQVLPNISLLVKIECNLLADRSKISLSSRKGDYFPNFDCRNQRRYLIVFTGPMWFPTAMLGPLLYISRTPELYYGPFHPLLNTYEQFPYLYQMAIKDTSIAIGMVTLVIYFSWNWVGLMISDDDLGLQFASELREEMQRYDICLAFVTVITYNSKLFLTMAGMYYNQIIMSLAKVVIIYGDIDSFLQVIFRLWQFVDIRRIWIATSQWDIITSNGEFLFNSFHGTLSFSHHYSEISGFKEFIQTVYPLNYSNTISPAKLWWVNFNCFWPSSNCKKLKKCSRKMLLKWLSNNQFEMAMSETNYNLYNAVYAVAHSLHELILQQANTLSNNVEKELEFDSLQVLSSLKKIQFVNPAGDLVNLNQKENLNVDYDIFYTGDFLQSYGIKVKIGNFFKYLTQPQKLLMFDEMVDWATDIRQTLPSICSTPCNPGFRKSPQEGKAVCCFDCNPCPENEISNMTDMDYCYKCLDNQYANSEGTHCLSKTVIFLSYEDPIGVTLACLALCFSALTAVVFGIFLRNQDTLIVKANNRALSYCLLISLIYCFLCSLLFIGKPHMVTCIMQQTIFAVAFTVAVSTVLSKTITVVLAFKFTLPSKKMRWLMTSGTSVLIIPICTMIQLIICGIWLGTYPPYVDSDGHIEHGHILIVCNKGSVTAFYCVLGYLGSIALASFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWLTFLPVYHSTSGKALVIVEVFCILTSTAGLLICIFAPKCYIILLTPKNNSFHTFRHNANVK", "length": 847 }, "evidence": [ { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PW21-1", "protein_name": "Vomeronasal 2, receptor 74", "gene_name": "Vmn2r74", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFLNSVFWLLKISFNFGHLSDPRCFWRIKDTENKLGDKETYCFFTISTKHGYVKNDYFRWNLDKKVTPKTRHLIFSVYLALEEINKNCHILPNISLVVNIECVLDKHDEKTDFLFKSEDLIPNYYCKNERRYLIVLTAPLWAVSSSIGPYLFMSRIPEVSQLYCGHFHLPLSDNEQYPHLHQISRKDTFLPLAMVSLVVHFRWNWIGVIVTNDDHGIQFLSEFRGEMQNKIVCLSFAIIIKTGKFLAVTELHMNYKQILMSSAKVVIVYGYRDSPIIYAFIVWKSQDLFRIWVSVSQLDMITFLGDFLLYASTGTFIFSHQKPEISGFEQFIQRIHPSNYSSEFSLAKQWWTYFRCSLPPSNCKKLKNCSTKTVFKWLFMTPLGLAMSDTCYNIYNAMYAVAHSLHGMLLQQVDTWSKNAGKELEFDSWKMFSILKTLKFVNPAGDLVNMNQNLKQDVEFDVFYIMDFQKDYGLKMKIGRFSEHLPSGQQIYMSKEMIEWATDIDQILPSICTMPCRPGLRKSPQEGKDICCFDCKPCSENEVSNMTNMDQCVKCPEDQYANEDHTVCLQKVVTILDYRDPLGKALAGFALCFSVLTSLVLVVFLKHRDTPIVKANNQTLSFVLLISLIFCFICSLLYIGHPTMAICILQQTTFAIVFTVATSTILSKTVIVILAFKITVPGRRMRWLLESGTPKYIIPICTIIQLILCGIWLGTSPPFVDADLHMVHGHILIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYIILLRPQKNYFYKFRKRRELNLTT", "length": 853 }, "evidence": [ { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q067-1", "protein_name": "Vomeronasal 2, receptor 79", "gene_name": "Vmn2r79", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLTFVFLVLKLSFLFCYLSDPRCFWRIKDRENYLGDKEADCFFSMYTKHGYVKNDYFSENLDKKVTLKTIHLISSVYFAAEEINRNSYILPNTSLIVKIECNLIADNVKRIWSLKKKEIIPNYYCKNQRRYLIVLTGPIWITSYILGPFLYFSQTPELYCGHFHLLLNDQEQFPHLYQMTPKDTSLPQGMVSLAVHFRWNWVGVIITDDDHGIQFLSELRAGMESNTVCLAFVTIITYNRKLYLKMYHKYYHQITMSSAKVVIVYGDKESPLQFNFILWKSENIQRLWVSVSQFDIITMIGEFMLNSVHGTLIFSHQQSEMSGFKQFMQTVHPSNYSNDISLAKLWWTYFKCSLPPPDCKTLKNCPTKTLLKRFFVPPLGMSMSETCYNLYNSVYAVAHSLHEMLLQQVDTCSENDGKVLEFNSWKMFSFLKTIQFVNPVGDLINMNQNRERDTEYDIFYIMDFLKHEGLKMKIGRFSGHFPNGQQLFISDEMIEWATDIKQTIASACSVPCRPGLRKYFQEGKAVCCFDCYPCPENEISNMTDMDQCLKCPEDEYANTDQTNCLKKVVTFLDYKEPLGMALTGLAVLFSSLTVVVLCVFLKHRDTPIVKANNETLSYVLLISLIFCFICSLLYIGYPSMVSCILQQTTFAMVFTVSASCVLAKTITVVLAFKITVPGRRLRWLLLSGAPNYIIPICTTIQMMLCGIWLGISPPFVDADLHMVHGHIIIVCNKGSVIAFYCVLGYMGSLALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFLPVYHSTKGKAMVAVEVFCILASSAGMLLCIFVPKCYLILWRPQINSFHEFRKMHVKNKNIN", "length": 851 }, "evidence": [ { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q281-1", "protein_name": "Vomeronasal 2, receptor 114", "gene_name": "Vmn2r114", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLLADFISPRCFWKMKQNENRDRNQGTGCTFMIHAVQRPVEKEYFSHILNIQTHAENYKNVLALAFSIYEINRNPDILPNMSVRFTISKYNCYWESELMSLIHLSLQNHDILPNYMCKELTRCTMALTRLNWVTTVKLNTILNNFISQQFFQITYGPFHPVLSDHEKFPYLYQMASDHTSLALALVSFIIHFSWNWVGLAISDNDQGIQFLSYLRRVMEKNAVCFAFVNMIPMSMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQIAFQKFDLPKDNGKEHNYSCKKLYSFLRKTQFTNPVGDRVNMNQRDKLQEEYDIFYIWNFPQGLELRVKIGMFSPYFPNGQQVHLSEDMIEWAKGSAQMPTSVCSAECGPGSRKFRMDGMAACSFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNHCIRKTVVFLSYEEPLGVALSLISLFFSAVTIVVLGVIVKHHSTPVVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGVVFTVSVSTVLAKTITVVLAFKITASQRMMKYFLVSGAINYIIPFCILIQVIVCAVWLGASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGRVMVAVEIFSILASSAGMLGCIFVPKCYTILFRPDQNSLEMIRAKSSSRAHIS", "length": 856 }, "evidence": [ { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3F5-1", "protein_name": "Vomeronasal 2, receptor 76", "gene_name": "Vmn2r76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIDMFSFISVFLVLKASMLFCSLNEPKCFLRIKDKKNKDGDKEVDCFFSIYTKHGHMKNEHFSGNLDKQLTTKNIHLILSLYFAIEEINMSPHLLPNISLLVKVECKLLADGSKVSLSSRRGDYFPNYNCGNHRRYLIVLTGPMWLPTAMLGPLLYISRTPEVRRLYYGPFHPLLSSFEHFPYLYQIAIKDTSVAIGMVSLVIYFGWNWVGLMISDDGLGLQFASELREEMQRYDICLAFVTIITYNTKLFLTMTDTYYNQIMMSLAKAVIIFGDKDSLLQVIFRLWQFLDIRRIWVTTSQWDIITSNGEFLFNSFHGTLSFSHHYSEIAGFKEFIQTAHPLNYSNTISLAKLWWLNFNCFLSSSNCKSLKTCSRKMLLKWLSRNHFEMSMSDTSYNLYNAVYAVAHSLNELLLQQANTLSNNVGKGLEFDSLQVLSSLKNIHFVNPAGDLVNLNQKENMNINYDIFYTGNFLQSFGIKVKIGKFFKYFTHPQELLMYEELVDWATDVRQTLPSICSIPCHPGFRKSPQEGKAVCCFDCIPCPENEISNMTDMDYCFKCPDNQYANPEGTHCLSKIVTFLSYEDPMGVVLACLALGFSALTAAVFGIFLRNQDTPIVKANNRALSYCLLISLIYCFLCSLLFIGQPHILTCIMQQTIFAVVFTVAISTVLTKTITVVLAFRFTLPSKRMRWLMTSGASILIIPICTMIQLIICGIWLGTSPPFVDSDGHIEHGHILVVCNKGSVIAFYCVLGYLGSIALTSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWLTFLPVYHSTNGKALVAVEVFCILTSTAGIFLCIFAPKCYIILLKPENKSFHKFRHKNANV", "length": 853 }, "evidence": [ { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3X931-1", "protein_name": "Vomeronasal 2, receptor 65", "gene_name": "Vmn2r65", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSFMSFFLILEYFLLLSVAHPKCFWRIKQNENKVGDVEDNCFFYIYTRQGPLLNDPFNGNPDILLTTRNIHLILALLFAIKQINRNIHILPNISLIVNVNCAKKEDLQMTNMYSNRDATIPNYNCKHGRRILTVLTGPRWFSSAILGPFLHIFAIPQLYYGPFHPLLSDREHYPYLYQMSPKNTFLTLAMTALVVYFSWNWVGLVISDDELGIEFLFKLRGEMHKHKVCIAFVNMIIQNIQLYQKRAEKYYNQILTSSAKVIIIYGDSDILTVHFRLWQHLGIKRLWITTSHWDENTSKGDLLLSSFNGIFIFSHPHSKIPGFKKFIQTVHPSNYSKDTSLARLWWLYFNCSLPSHCKTLKNCSTKILLEWLSRHQFEVSMSEPSYNLYNAVYAVAYALHEMLIQHTEHWQKDIGKELEFYSWKVAPFLENNKFIIPSEYQYRRGKLDTEYDILYAMDLLPALGLNVKIGKFSQHFLHFQQLYIAEDMIDWTIDIRQTLQSVCSVPCSVGFRKFIQKGKAVCCFDCTPCPENEISNMTDMDQCVKCPNDQYANIKQTHCLKKVVTFLAYEDPLGMTLTCLALLFSALTTVILSILLKHQDNPIVKANNRLLSYILLISLIFCFLCSLLYIGHPHMATCILQQTTFAVVFTVAVSTILAKTITVVMAFKITDPRKKIRQMLVTRAPNYIIPICTMIQLILCGTWIGTSPPFVDSDPHFEHGHIIIVCNKGSVIAFYCVLGYLGLLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTKGKAMVVVEIFSILTSSAGLLVCIFFPKCFTILLKQKVNFTQKFSDTHSKIEYNH", "length": 845 }, "evidence": [ { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3XA45-1", "protein_name": "Vomeronasal 2, receptor 69", "gene_name": "Vmn2r69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVIWFLKIKLMFCHLSDPSCFWRIKETENDLGDTETYCLFSISTKQGYVKNDYFSWNIDKKVTPKTNHLIFSVYLALEEVNKNCHILPNISLLVNIECNGRKYDEKTGLALKIENIIPNYSCTNERTYLIVLTAPIWAVSTKLGPFLFMSRIPELYCGHFHPLLSDNEEFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGVIVTSDDQGIQFLSELKGEMQKNIVCLSVAIIIQTEMSMALKELSMNYKHISISSAKVVIVYGDKFSPINYALTLWISQGILRIWVSVSQFDMITILGDFLLYSSTGTFIFSHQQPEIPGFEKFIQTVYPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKTIFTWLFRTPFGMAMSDTCYNSYNAIYAVAHSLHEMLMQEVDTWSNNAGKELEFDSWKMFSILKTLKFVNPAGDLVNMNQNLKQATQYNIFYVMDFQKDYGLKMKIGRFSEHLPSGQQLYMSKEMIEWATDIDQILPSICSMPCTPGLRKSPQEGKDICCFVCIPCPENEISNMTNMDQCVKCLEDQYANEDHTLCLQKVVAILDYRDPLGKALAGFALCFSLLTSVVLFVFLKHRDTPIVKANNQTLSIVLLISLIFCFICSLLYIGHPTMVICILQQTTFAIAFTVATSTILAKTITVVLAFKITVPGRRMRWLLVSGAPKYIILICTMIQLILCGIWLGTSPPFVDADVQMVHGHIIIVCNKGSVIAFYCVLGYMGSVALAGFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWMTFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYFILRPQTNSFHKFRKPHAKTENKS", "length": 850 }, "evidence": [ { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8Z7-1", "protein_name": "Vomeronasal 2, receptor 75", "gene_name": "Vmn2r75", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNTFSLISVFWFLKISIIFCHLSDPRCFWRIKDAKNDLGDKETYCFFSIYTKQGYVKNDYFSWNLDKKVTPKTNHLIFSVYLAMEEINKNGHILPNISLLVNIECGLELYGERTGLAFKSEEFIPNYYCRNHRKYLIVLTTPKWGVSTSLGPLLYISRVPELYCGHFHLLLNDNEQFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGAIVTNDDHGIQFLSELRGEMQKHIVCLSVAIIIQTEKFMALKEFRMNYNKIAMSSATVVIVYGDKDSPIQFTLIMWKSEGIWRIWVSVSQFDMITVIGDFLLYSSTGSFIFSHQQSEISGFEKFIQTVHPSNYSSEFSLAKLWWTYFTCSLPPSNCKKLKNCPIKTVFKWLFMTPIGMSMSDISYNLYNAMYAVAHSVHEMLLQQVDIWSTNAGTELEFDSWKMFSILKTLKFVNPAGDLVNMNQNLKQDTEYDIFYIPNFQKYYGLKMKIGRFSGYLPSGQQLYMSKEMMEWATDMDQILPSICSMPCRPGLRKSPQEEKDICCFVCNPCPENEISNMTNMDQCVKCPEDQYANEDQTLCLQKVVDVLDYRDPLGKSLAGFALCFSVLTSIVLCVFLKHRESPIVKANNQTLSYVLLISLIFCFICSLLYIGHPTMFICILQQTAFAIAFTVAASTVLAKTITVILAFKITVPGRMRWLLVSGAPKYIIFVCTMIQLIFCGIWLGTSPPFVETDVHMTHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLSRKLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIYAPKCYIILLRPQKNSFYKFRKPHSKSENIS", "length": 853 }, "evidence": [ { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T2-1", "protein_name": "Vomeronasal 2, receptor 67", "gene_name": "Vmn2r67", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKISFMFCHLSDPKCFWRIKDTKKNLGDTETYCSFSISTKRGYVKNDYFSWNLDKQVTPKTNHLIFSVYLALEEINMNFHILPNISLVVNIECLRKKYDEKTGLALQTEEFIPNYYCTDERRYLIIFTAPIWAVTTRLGTFMFMYSIPELYCGHFHLSLSDNEQFPHLYQISPKDTSLPLAMVSLMVHFRWNWIGAIVTTDDHGIQFLSELRGEMQKHIVCLSFEITILTEHSMARKEFQRYFNRIVMSSAKVVIVYGDYTSPIDLVLHLCKSKGIFRIWVSVSQFDMITKLGDFMLYSSSGTFIFSHQKPELSGFQQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKIVFKWLFMTPLGMAMSDTCYNLYNAIYAVAHSLHEMLLQQIDTWSNNAGKELEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTDYDIFYIMDFQKDYGFKMKIGRFSGHLPSHQQLYMSKEMMEWATDVDQILPSICSMPCRPGLRKSPEEGKDICCFVCNPCHENEISNMTNMDQCVKCQEDQYANEDHTLCLQKVVSILDYRDPLGKALAGIALCFSVLTSGILCIFLKHRETPIVKANNQTLSYVLLISLVFCFICSLLYIGHPTTVICILQPITFAIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLLSGVPKYIVLICTMIQLILCGIWLGTSPPFVDADVYMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFSILASSAGLLLCIFAPKCYIILLRPQTNSFHKFRKTHSKAENIS", "length": 851 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U5-1", "protein_name": "Vomeronasal 2, receptor 78", "gene_name": "Vmn2r78", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLIVVFLLLKLSFLFCSLSDPRCFWRIKDRENDLGDKETDCFFSIYTKRGYVKNDYFSENLDKKVTLKTIHLISSVYFAAEEINKNIYILPNISLIVKIECNLIADNVKRIWSLKKKEIIPNYYCKNQRRYLIVLTGPIWITSYILGPFLYFSQTPELYCGHFHFLLNDQEQFPHLYQMTPKDTSLPQGMVSLAVHFRWNWVGVIITDDDHGIQFLSELRTGMESNTVCLAFVTIITYNRMLYLKMYHKYYHQITMSSAKVVIVYGDKESPLQFNFILWKSENIQRLWVSVSQFDMITVIRDFMLNSLHGTLIFSHQQSEISGFKQFMQTVHPSNYSNDISLAKMWWTYFKCSLKPPDCKTLKNCPTKTLFKWFFVPPLGMSMSETCYNLYNSVYAVAHSLHEMLLQQVDTCSENDGTVMEFNSWKMFYFLKTIQFVNPAGDLINMNQNRERDTEYDIFYIMDFLKHEGLKMKIGRFSGHFPNGQQLFMSDEMIEWATDIKQTLASACSVPCRPGLRKYFQEGKAVCCFDCYPCPENEISNMTDMDQCVKCPEDEYANTDQTNCLKKVVTFLDYKEPLGMALAVLAVFFSSLTFIILCVFLKHRDTPIVKANNETLSYVLLTSLIFCFICSLLYIGYPTMVSCILQQTTFALVFTVAASCVLAKTITVVLAFKITVPGRRLRWLLLSGAPNYIIPICTTIQMILCGIWLGTSPPFVDADLHMIHEHIIIVCNKGSVTAFYCVLGYMGSLALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWVTFLPVYHSTKGKAMVAVEVFCILASSAGMLLCIFVPKCYLILLRPQINSFHEFRKIHAKSININRM", "length": 853 }, "evidence": [ { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6V1-1", "protein_name": "Vomeronasal 2, receptor 117", "gene_name": "Vmn2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLVSDFIYPRCFWKIKQNEDKNRNQGTECTFMIHAVQRPVEKEYFSHILNIQTHTENHKYALALAFSIYEINRNPDILPNMSLTFKFSNYNCHWKSKYNSFIHLSLQNHDILPNYMCKEFTKCAMALTRLNWATTVKLNTILNNFMSQQFLQITYGPFHPVLSDHEKFPYLYQMASDHTSLALALVSFIIHFSWNWVGLVISDNDEDIQFLSYLRREMEKNTVCFAFVNMIPMSMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQIAFQKLDNLPKDNGKEHNYSCKKLYSFLRKTQFTNPVGDRVNMNRRNKLQEEYDIFYIWNFPQGLGLRVKIGMFSPYFPNGQQVHLSEDMIEWAKGSAQVPTSVCSAECGPGSRKFRMDGMAACCFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNQCIRKTVVFLSYEEPLGMALSLLSLCFSAFTTVVLGVMVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGVVFTVSVSTVLAKTITVVLAFKITASQRMMKYFLVSGAINYIIPICILIQVIVCAVWLRASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYYSTKGKVMVAVEIFSILASSAGMLGCIFVPKCYTILFRPDQNSLEMIRVKSSSNAHVS", "length": 857 }, "evidence": [ { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N702-1", "protein_name": "Vomeronasal 2, receptor 70", "gene_name": "Vmn2r70", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLNSVFWFLKISFIFCHLSDPRCFWRIKDTENNIGDTETYCFFSISTKHGYVKNDYFSWNLDKQVTPKTRHLIFSVYLALEEINDSFHILPNISLVVNIECVLQKYGEKTGLLLRSEKLIPNYYCINERRYLIVLTAPTWAISTKLGPFLFMSRIPEVNQLYCGHFHLPLSNNEQFPHLYQISKKDTSLPLAMVSLVVHFRWNWIGVIITNDDHGIQFLSELRGEMQNNIVCLSVVITIKTQKLVALKELHMNYKQILMSSAKVVIVYGYKDSPIIYALISWKSHGIFRIWVSVSQFDMITIRGDFLLYSSTGTFIFSHQKPEISGFEQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSDCKKLKNCPTKTVFKWLFMTPLGMAMSDTCYNLYNAVYGVAHSLHEMLLQQVDAWSKNAGKELEFDPWKMFSVLKTIQFINPAGDLVNMNQNLRQDVEYDVFYIMDFQKVYGLKMKIGRFSGQLSSGQQLYMSKEIIEWATDIDQILPSICSMPCRPGLRKSPQEEKDICCFGCNPCPENEISNMTNMDQCVKCPENQYANEDHTLCLEKVVAILDYKDPLGKALAGFALCFSVLTSVVLGIFLKNRDTPIVKANNQSLSFVLLISLIFCFICSLLYIGHPTMVICILQQTTFAIVFTVATSTILAKTVIVVLAFKITVPGRRMRWLLEIGAPKYIILICTIIQLILCGIWLGTSPPFVDADVHMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFSILASSAGLLLCIFAPKCYIILLKPQKNSFQKFRKPHAIADNIS", "length": 854 }, "evidence": [ { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B3-1", "protein_name": "Vomeronasal 2, receptor 68", "gene_name": "Vmn2r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVIWFLKVKLMFCHLSDPKCFWRIKDTENNLGDTETYCSFSISTRHGYVKNDYFSWNLDKKVTPKTNHLIFSVYLALDEINMNIHILPNISMVANIECFLQKDGEKTGLALQRKEFIPNYYCTDERRYLIIFTAPIWAVTTRLGPLMFMYSIPELYCGHFHLSLNDNEQFPHLYQISPKDTSLPLAMVSLMVHFRWNWIGAMITNDDHGIQFLSKLRGEMQKHIVCLSFVITILTEHSMAHKEFQRYFNRIVMSSAKVVIVYGDYTSPIDLVLHLCKSKGIFRIWVSVSQFDMITYLGDFMLYSSSGTFIFSHQKPELSGFQQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPFNCKKLKNCPTKIVFKWLFMTPLGMAMSDTCYNLYNAIHAVAHSLHEMLLQQVDTWSNNAGKELEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTEYEIFYIMDFQKDYGLKMKIGRFSGHLPSRQQLYMSKEMMEWAIDVDQILPSICSMPCRPGLRKSPQEEKDICCFVCNPCLENEISNMTNMDQCVKCREDQYANEHHTLCLQKVVSILDYRDPLGKALAGIALCFSFLTSVVLCIFLKHRETPIVKANNQTLSYVLLISLVFCFICSLLYIGHPTAVICILQQTTFVIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLVSGAPKYIILICTMIQLILCGIWLGTSPPFVDADAHMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYIILLRPDINSFQKFRKPHANAENIS", "length": 851 }, "evidence": [ { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B7-1", "protein_name": "Vomeronasal 2, receptor 77", "gene_name": "Vmn2r77", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEMFSLIVFFLVLKLSFLFCYLSDPRCFWRIKDRENYLGDKEADCFFSIYTKRGYVKNDYFSENLDKKVTLKTIYLISSVYFAIEEINRNIHILPNISLLVKIDCNLIEDNVERVWSLKKKEIIPNYYCKNQRRYLIVLTGPIWITSYILGPFLYFSRTPELYCGYFHLLLSDQEQFPHLYQMTPKDTSLPLAMVSLAVHFRWNWVGVIITDDDHGIQFLSELRTGMERNTVCLAFVTSITYDKMLYLKMTHKYYHQIIMSSAKVVVVYGDKESPLQLNFMLWKSINIQRLWVSVSQFDMITMMGDFMLNSIHGTLIFSHQQSEMSGFKHFIQRVNPSNYSNDISLAKLWWTYFKCSLPPPDCKTLKNCPTKTLFQWFFEPPLGMSMSETCYNLYNSVYAAAHSIHEMLLQHVDTSSENDENVLEFNSWKMFSFVKNIQFVNPAGDLVNMNQNRKLDTEYDIFYITDFLKHEGLKMKIGRFSGHFPNGQQLFISDEMIEWATDIKQTLASICSVPCRPGLRKYFQEGNSVCCFDCYPCPENEISNMTDMDQCVKCPEDEYANTNQTKCFKKVVTFLAYEDPSGMALAVLAVCFSVLTSVVLCVFLKHRNTPIVKANNETLSYVLLTSLIFCFICSLLYIGYPTMVSCILQQTTFAIVFTVAASCVLAKTITVVLAFKITVPGRRLRWLLLSGAPNYIIPICTMIQMILCGIWLGTSPPFVDADLHMVHGHIIIVCNKGSVIAFYCVLGYMGSLALSSFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFLPVYHSTKGKAMVAVEVFCILASSAGMLVCIFLPKCYIILLRPQINSFHDFRKIHVKVININ", "length": 854 }, "evidence": [ { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2D8-1", "protein_name": "Vomeronasal 2, receptor 71", "gene_name": "Vmn2r71", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKVNFIFCHLSDPRCFWRIKETENKLGDKETFCLFSISTKQGYVKNDYFSWNLDKQVTPKINHLIFSVYLALEEINKNCHILPNISLLVNTECNGRKYDEKTGLALKSEKIVPNYSCTNERRYLIVLTAPIWAVSTKLGPFLYISRIPELYCGHFHLLLSDKGQFPHLYQISPKDTSLPLAMVSLFVHFRWNWIGVIITNDDHGIQFLSELKGDMQKSIVCLSVAIIIQTEVYMALKELHMNYKKILMSSAKVVIVYGDKDSPIKYVLTAWKSQGIFRIWVSASQFDMITILGDFLLYSYTGTFIFSHQQPEIPGFEKFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKSVFAWLFRTPLGMAMSDTCYNSYNAIYAVAHSLHEMLLQEVDTWSKNAGKELEFDSWKMFSILKTLKFVNPSGDLVNMNQNLKQDTEYDIFYIMDFQKDYGLKMKIGRFSGHLLSGQQLYMAKEMMEWATDIDQILPSICSVPCSPGLRKSPQEGKDICCFVCNPCPENEISNMTNMDQCVKCLEDQYANEDHTLCLQKVVVIFDYRDPLGKALAGFALCFSVLTSVVLFVFFKHRDTPIVKANNQTLSFVLLISLIFCFICSLLYIGHPTMVTCIVQQITFAIGFTVATSTILAKTVIVVLAFKITVPGRRMRWMPESGAPKYIILICTMIQLILCGIWLGTSPPFVDADVQMVHGHIIIICNKGSVIAFYCVLGYMGSLALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKIMAVVEVFCILASSAGLLLCIFAPKCYIILLRPQTNYFHKFWKSHANSENKS", "length": 851 }, "evidence": [ { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-208", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1LV89-1", "protein_name": "Olfactory receptor CQ3 precursor", "gene_name": "olfcq3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLNICLHLSFIFISVNSDSCQIQGHFKLNRMYKDGDYIIGGLFEVQHLKVFPELSFRMEPEQPKCEEFYMSSFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCLKLVVAFRAATTLISGTEETFSNFNCTGPPPVIAIVGDPGSTHSIAVSSVLGLFHVPLISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMVQILKYFGWTWVGVLYSDDDYGIYAAQSFQQEMQRFKGCVAFSEIVPYDNHRDIQRIVAVIKASTARVVVAFSTDLLPLMEELLQQNVTGRQWIASEAWSTSPVLHLPRFVPLVRGTLGIAIHRGKIKGLHEFLLHIQPDNDPTNNMVRIFWENMFGCSFEKGNGYGEKMCTAQEDLNITVNEYNDVSELRASYNVYKAVYALAHALHDLMQCEEGRGPFSGNSCADITKLKPWQMVPYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWHPSSDGLIVVRTVGVVDEGASAGRVLTLDEDAIYWNFETKKPPRSVCSESCPPGTRRAMRKGLPVCCFDCLPCADGEISNMSDATECTSCPNEFWSSPKKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVLAVFAHHHNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAMFGISFVLCVSSILVKTMVVIAVFKSSRPEGKSAVKWFGAVQQRGTVLVLTAVQIVICVVWLSTASPTPHKNILYVRSKIVFECSIGSMAGFAILLGYIGILAAVSFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFIPAYVSSPGKYSVAVEIFAILASSFGLLVAIFVPKCYIIILHPERNTKKAIMGRTAEK", "length": 855 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD42" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 455, "end_pos": 457, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PD42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD42" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 598, "end_pos": 863, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 156 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 455, "end_pos": 457 }, { "start_pos": 561, "end_pos": 563 }, { "start_pos": 632, "end_pos": 634 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. 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Classification" ] }, { "id": "A0A8M9PI62", "url": "https://www.orthodb.org/?gene=A0A8M9PI62", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F9X6", "url": "https://www.orthodb.org/?gene=E7F9X6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13239", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13239", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13239:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13239:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11882", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11882", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021331082", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331082", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PI62", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PI62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J979", "url": "https://www.uniprot.org/uniprotkb/A0AC58J979", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J979-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J979-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J980", "url": "https://www.uniprot.org/uniprotkb/A0AC58J980", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J980-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J980-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J985", "url": "https://www.uniprot.org/uniprotkb/A0AC58J985", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J985-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J985-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F9X6", "url": "https://www.uniprot.org/uniprotkb/E7F9X6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F9X6-1", "url": "https://www.uniprot.org/uniprotkb/E7F9X6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X1WE96", "url": "https://www.uniprot.org/uniprotkb/X1WE96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X1WE96-1", "url": "https://www.uniprot.org/uniprotkb/X1WE96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120328-1", "url": "https://zfin.org/ZDB-GENE-120328-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MQQTDDMEVPLIHDSNSNTHTCLPQERDGFHQQKDSEGSMESPNLEFEYGDTDSFTAELSELYSYTEEPEFSLNRDYFEEDFKNHVKGRRWMELSVEEQRAYVMRLLDALEVTDRDKRLKVARAILYLAQGVFDECDTETDVLYWSRHNVFLLYDMGIFTALLELLSMEIDNNQACSSAVRKPAISLADSTELRVLLSIMYLMVETIRVEMESDSPERKAAREAFKMELGSPLYNGEPFALLLFTMVTKFCSMNAPHFPMKKVLLLLWKTILFTLGGFEELQEMKVRMRDHLNLPPLPEDSIKVVRNMRAASPPASAMELIEQQQQQKRGRRSRRSAFVDSLEGDSPYAKKQPLVKQDSLDTYNERDPFKNDDARDEEDDPEDVDSGIEGEVDPLDRDVIIQPPPPPPPLRPPTERMSFPKGLPWAPKVREKDIEHFLETSRNKFIGFTLGNDIDTLVGLPRPIHESVKTLKLHKYVSIAEVQIKREDELQQCPMTMGEEEVEETPTEILYLGMLPSLSQYVIALLKLLLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKAISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNIMSYISAKNSICALDFPHCAVHEMPELTAESLEAGDSNQFCWRNLFSCINLLRILNKITKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDIDARPWDFQAEECALRESIEKFNTRRYDKNQNSEFAPVDNCLQSVLGQRVDLPEDFHYSYEMWLEREVFSQPIQWEGLLQAQ", "length": 839, "header": "tr|A0A8M9PI62-1|A0A8M9PI62_DANRE Isoform 1 of Striatin-interacting protein 1 homolog isoform X1 OS=Danio rerio OX=7955 GN=strip2 PE=3 SV=1 CANONICAL=A0A8M9PI62-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PI62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62/entry#A0A8M9PI62-1", "sequence": { "sequence": "MQQTDDMEVPLIHDSNSNTHTCLPQERDGFHQQKDSEGSMESPNLEFEYGDTDSFTAELSELYSYTEEPEFSLNRDYFEEDFKNHVKGRRWMELSVEEQRAYVMRLLDALEVTDRDKRLKVARAILYLAQGVFDECDTETDVLYWSRHNVFLLYDMGIFTALLELLSMEIDNNQACSSAVRKPAISLADSTELRVLLSIMYLMVETIRVEMESDSPERKAAREAFKMELGSPLYNGEPFALLLFTMVTKFCSMNAPHFPMKKVLLLLWKTILFTLGGFEELQEMKVRMRDHLNLPPLPEDSIKVVRNMRAASPPASAMELIEQQQQQKRGRRSRRSAFVDSLEGDSPYAKKQPLVKQDSLDTYNERDPFKNDDARDEEDDPEDVDSGIEGEVDPLDRDVIIQPPPPPPPLRPPTERMSFPKGLPWAPKVREKDIEHFLETSRNKFIGFTLGNDIDTLVGLPRPIHESVKTLKLHKYVSIAEVQIKREDELQQCPMTMGEEEVEETPTEILYLGMLPSLSQYVIALLKLLLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKAISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNIMSYISAKNSICALDFPHCAVHEMPELTAESLEAGDSNQFCWRNLFSCINLLRILNKITKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDIDARPWDFQAEECALRESIEKFNTRRYDKNQNSEFAPVDNCLQSVLGQRVDLPEDFHYSYEMWLEREVFSQPIQWEGLLQAQ", "length": 839, "header": "tr|A0A8M9PI62-1|A0A8M9PI62_DANRE Isoform 1 of Striatin-interacting protein 1 homolog isoform X1 OS=Danio rerio OX=7955 GN=strip2 PE=3 SV=1 CANONICAL=A0A8M9PI62-1" }, "locus": {} }, { "isoform_ac": "A0AC58J979-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62/entry#A0AC58J979-1", "sequence": { "sequence": "MQQTDDMEGSMESPNLEFEYGDTDSFTAELSELYSYTEEPEFSLNRDYFEEDFKNHVKGRRWMELSVEEQRAYVMRLLDALEVTDRDKRLKVARAILYLAQGVFDECDTETDVLYWSRHNVFLLYDMGIFTALLELLSMEIDNNQACSSAVRKPAISLADSTELRVLLSIMYLMVETIRVEMESDSPERKAAREAFKMELGSPLYNGEPFALLLFTMVTKFCSMNAPHFPMKKVLLLLWKTILFTLGGFEELQEMKVRMRDHLNLPPLPEDSIKVVRNMRAASPPASAMELIEQQQQQKRGRRSRRPLVKQDSLDTYNERDPFKNDDARDEEDDPEDVDSGIEGEVDPLDRDVIIQPPPPPPPLRPPTERMSFPKGLPWAPKVREKDIEHFLETSRNKFIGFTLGNDIDTLVGLPRPIHESVKTLKLHKYVSIAEVQIKREDELQQCPMTMGEEEVEETPTEILYLGMLPSLSQYVIALLKLLLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKAISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNIMSYISAKNSICALDFPHCAVHEMPELTAESLEAGDSNQFCWRNLFSCINLLRILNKITKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDIDARPWDFQAEECALRESIEKFNTRRYDKNQNSEFAPVDNCLQSVLGQRVDLPEDFHYSYEMWLEREVFSQPIQWEGLLQAQ", "length": 793, "header": "tr|A0AC58J979-1|A0AC58J979_DANRE Computationally mapped isoform of Striatin-interacting protein 1 homolog isoform X6 OS=Danio rerio OX=7955 GN=strip2 PE=3 SV=1 CANONICAL=A0A8M9PI62-1" }, "locus": {} }, { "isoform_ac": "A0AC58J980-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62/entry#A0AC58J980-1", "sequence": { "sequence": "MQQTDDMEKSRLLRPGNISPIFNCPILGSMESPNLEFEYGDTDSFTAELSELYSYTEEPEFSLNRDYFEEDFKNHVKGRRWMELSVEEQRAYVMRLLDALEVTDRDKRLKVARAILYLAQGVFDECDTETDVLYWSRHNVFLLYDMGIFTALLELLSMEIDNNQACSSAVRKPAISLADSTELRVLLSIMYLMVETIRVEMESDSPERKAAREAFKMELGSPLYNGEPFALLLFTMVTKFCSMNAPHFPMKKVLLLLWKTILFTLGGFEELQEMKVRMRDHLNLPPLPEDSIKVVRNMRAASPPASAMELIEQQQQQKRGRRSRRSAFVDSLEGDSPYAKKQPLVKQDSLDTYNERDPFKNDDARDEEDDPEDVDSGIEGEVDPLDRDVIIQPPPPPPPLRPPTERMSFPKGLPWAPKVREKDIEHFLETSRNKFIGFTLGNDIDTLVGLPRPIHESVKTLKLHKYVSIAEVQIKREDELQQCPMTMGEEEVEETPTEILYLGMLPSLSQYVIALLKLLLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKAISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNIMSYISAKNSICALDFPHCAVHEMPELTAESLEAGDSNQFCWRNLFSCINLLRILNKITKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDIDARPWDFQAEECALRESIEKFNTRRYDKNQNSEFAPVDNCLQSVLGQRVDLPEDFHYSYEMWLEREVFSQPIQWEGLLQAQ", "length": 829, "header": "tr|A0AC58J980-1|A0AC58J980_DANRE Computationally mapped isoform of Striatin-interacting protein 1 homolog isoform X2 OS=Danio rerio OX=7955 GN=strip2 PE=3 SV=1 CANONICAL=A0A8M9PI62-1" }, "locus": {} }, { "isoform_ac": "A0AC58J985-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62/entry#A0AC58J985-1", "sequence": { "sequence": "MQQTDDMEKSRLLRPGNISPIFNCPILGSMESPNLEFEYGDTDSFTAELSELYSYTEEPEFSLNRDYFEEDFKNHVKGRRWMELSVEEQRAYVMRLLDALEVTDRDKRLKVARAILYLAQGVFDECDTETDVLYWSRHNVFLLYDMGIFTALLELLSMEIDNNQACSSAVRKPAISLADSTELRVLLSIMYLMVETIRVEMESDSPERKAAREAFKMELGSPLYNGEPFALLLFTMVTKFCSMNAPHFPMKKVLLLLWKTILFTLGGFEELQEMKVRMRDHLNLPPLPEDSIKVVRNMRAASPPASAMELIEQQQQQKRGRRSRRPLVKQDSLDTYNERDPFKNDDARDEEDDPEDVDSGIEGEVDPLDRDVIIQPPPPPPPLRPPTERMSFPKGLPWAPKVREKDIEHFLETSRNKFIGFTLGNDIDTLVGLPRPIHESVKTLKLHKYVSIAEVQIKREDELQQCPMTMGEEEVEETPTEILYLGMLPSLSQYVIALLKLLLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKAISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNIMSYISAKNSICALDFPHCAVHEMPELTAESLEAGDSNQFCWRNLFSCINLLRILNKITKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDIDARPWDFQAEECALRESIEKFNTRRYDKNQNSEFAPVDNCLQSVLGQRVDLPEDFHYSYEMWLEREVFSQPIQWEGLLQAQ", "length": 812, "header": "tr|A0AC58J985-1|A0AC58J985_DANRE Computationally mapped isoform of Striatin-interacting protein 1 homolog isoform X4 OS=Danio rerio OX=7955 GN=strip2 PE=3 SV=1 CANONICAL=A0A8M9PI62-1" }, "locus": {} }, { "isoform_ac": "E7F9X6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62/entry#E7F9X6-1", "sequence": { "sequence": "MQQTDDMEGSMESPNLEFEYGDTDSFTAELSELYSYTEEPEFSLNRDYFEEDFKNHVKGRRWMELSVEEQRAYVMRLLDALEVTDRDKRLKVARAILYLAQGVFDECDTETDVLYWSRHNVFLLYDMGIFTALLELLSMEIDNNQACSSAVRKPAISLADSTELRVLLSIMYLMVETIRVEMESDSPERKAAREAFKMELGSPLYNGEPFALLLFTMVTKFCSMNAPHFPMKKVLLLLWKTILFTLGGFEELQEMKVRMRDHLNLPPLPEDSIKVVRNMRAASPPASAMELIEQQQQQKRGRRSRRSAFVDSLEGDSPYAKKQPLVKQDSLDTYNERDPFKNDDARDEEDDPEDVDSGIEGEVDPLDRDVIIQPPPPPPPLRPPTERMSFPKGLPWAPKVREKDIEHFLETSRNKFIGFTLGNDIDTLVGLPRPIHESVKTLKLHKYVSIAEVQIKREDELQQCPMTMGEEEVEETPTEILYLGMLPSLSQYVIALLKLLLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKAISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNIMSYISAKNSICALDFPHCAVHEMPELTAESLEAGDSNQFCWRNLFSCINLLRILNKITKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDIDARPWDFQAEECALRESIEKFNTRRYDKNQNSEFAPVDNCLQSVLGQRVDLPEDFHYSYEMWLEREVFSQPIQWEGLLQAQ", "length": 810, "header": "tr|E7F9X6-1|A0A8M9PI62_DANRE Computationally mapped isoform of Striatin-interacting protein 1 homolog isoform X1 OS=Danio rerio OX=7955 GN=strip2 PE=3 SV=1 CANONICAL=A0A8M9PI62-1" }, "locus": {} }, { "isoform_ac": "X1WE96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62/entry#X1WE96-1", "sequence": { "sequence": "MQQTDDMEVPLIHDSNSNTHTCLPQERDGFHQQKDSEGSMESPNLEFEYGDTDSFTAELSELYSYTEEPEFSLNRDYFEEDFKNHVKGRRWMELSVEEQRAYVMRLLDALEVTDRDKRLKVARAILYLAQGVFDECDTETDVLYWSRHNVFLLYDMGIFTALLELLSMEIDNNQACSSAVRKPAISLADSTELRVLLSIMYLMVETIRVEMESDSPERKAAREAFKMELGSPLYNGEPFALLLFTMVTKFCSMNAPHFPMKKVLLLLWKTILFTLGGFEELQEMKVRMRDHLNLPPLPEDSIKVVRNMRAASPPASAMELIEQQQQQKRGRRSRRPLVKQDSLDTYNERDPFKNDDARDEEDDPEDVDSGIEGEVDPLDRDVIIQPPPPPPPLRPPTERMSFPKGLPWAPKVREKDIEHFLETSRNKFIGFTLGNDIDTLVGLPRPIHESVKTLKLHKYVSIAEVQIKREDELQQCPMTMGEEEVEETPTEILYLGMLPSLSQYVIALLKLLLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKAISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNIMSYISAKNSICALDFPHCAVHEMPELTAESLEAGDSNQFCWRNLFSCINLLRILNKITKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDIDARPWDFQAEECALRESIEKFNTRRYDKNQNSEFAPVDNCLQSVLGQRVDLPEDFHYSYEMWLEREVFSQPIQWEGLLQAQ", "length": 822, "header": "tr|X1WE96-1|A0A8M9PI62_DANRE Computationally mapped isoform of Striatin-interacting protein 1 homolog isoform X1 OS=Danio rerio OX=7955 GN=strip2 PE=3 SV=1 CANONICAL=A0A8M9PI62-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:556392", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556392", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G7M4-1", "protein_name": "Striatin interacting protein 2", "gene_name": "Strip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDPAAPGPSGSPANDNGNGNGNGNGNGNGGKGKPAVPKGREAFRNQRRESEGSVDCPTLEFEYGDADGHAAELSELYSYTESLEFTTNRKCFEEDFKTQVQDTKEWLELEEDAQKTYVMGLLDRLEVVSREQRLKVARAVLYLAQGTFGECDSEVDVLHWSRYNCFLLYRMGTFSAFLELLHMEIDNSQASSSALRKPAVSIADSTELRVLLSVMYLMVENIRLEREIDPCGWRTARETFRTELSFSTHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKIQKRAELGLPPLAEDSIQVVKSMRAASPPSYTLDLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESASDGERTLDGELDLLEQDPLVPPPPSQTPLSADRVSFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADVQIKNEEELEKCPMSLGEEVIPETPSEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPATVLQSMKLGIDVNRHKEIIVKSISALLLLLLKHFKLNHIYQFEYVAQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAGDNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDKPQDSEFSPVDNCLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "length": 844 }, "evidence": [ { "id": "MGI:2444363", "url": "https://alliancegenome.org/gene/MGI:2444363#orthology", "database": "AGR" }, { "id": "HGNC:22209", "url": "https://alliancegenome.org/gene/HGNC:22209#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120328-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120328-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0035437", "url": "https://alliancegenome.org/gene/FB:FBgn0035437#orthology", "database": "AGR" }, { "id": "RGD:1588437", "url": "https://alliancegenome.org/gene/RGD:1588437#orthology", "database": "AGR" }, { "id": "SGD:S000005071", "url": "https://alliancegenome.org/gene/SGD:S000005071#orthology", "database": "AGR" }, { "id": "A0A8M9PI62", "url": "https://omabrowser.org/oma/group/A0A8M9PI62/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BIK9-1", "protein_name": "Striatin interacting protein 2", "gene_name": "STRIP2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEDPAAPGAGNPPTNGNGNGGGKGKPAAPKGREAFRSQRRESEGSVDCPTLEFEYGDADGHAAELSELYSYTENPEFTTNRRCFEEDFKTQVQGEEWLELEEDAQKAYVMGLLDRLEVVSRERRLKVARAVLYLAQGTFGECDSEVDVLHWSRYNCFLLYQMGTFSAFLELLHMEIDNSQACSSALRKPAISIADSTELRVLLSVLYLMVENIRLERETDSCGWRTARETFRTELSFSTHNQEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKVQKRAELGLPPLAEDSIQVVKSMRAASPPSYTLDLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESASDGERTLDGELDLLEQDPLVPPPPSQAPLSAERVAFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYVSIADVQIKNEEELEKCPMSLGEEVVPETPCEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKSISALLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNGISVLDYPCCTIQDLPELTTESLEAGDNNQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDRPQDSEFSPVDNCLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "length": 834 }, "evidence": [ { "id": "A0A8M9PI62", "url": "https://omabrowser.org/oma/group/A0A8M9PI62/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3V8E2-1", "protein_name": "Striatin-interacting protein 1", "gene_name": "Strip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKGKTSGGDWQLRLSTHAATLNMAIGEISWRKSRESCLTEAIRELSRGCGAAKMEPAAAGPGPLIVNNKQPQPPPPPPPATAQPPPGAPRAAGGLLPAGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELAELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQFWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQDCDGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRTLLGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGEAFPLERDEVMPPPLQHPPTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTDTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVNELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRTHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "length": 892 }, "evidence": [ { "id": "FB:FBgn0035437", "url": "https://alliancegenome.org/gene/FB:FBgn0035437#orthology", "database": "AGR" }, { "id": "SGD:S000005071", "url": "https://alliancegenome.org/gene/SGD:S000005071#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P53917-1", "protein_name": "Factor arrest protein 11", "gene_name": "FAR11", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNASGRSHSKGPIIRSVSLEDLKRNSSFKGNLKYKDEVTSHKEPQVGTLSNEELLKDLDNMLRGKLNMGRNSFHADKRNKSDGNISALTFKARSGLEGDIRTIDIQQDSSDENDNFKFSDDGVNKDRNNEKDNNTDNAVEFQDDAEEAEEENEDESFANVDELDGFDLNKVSDGKHVPINEKGEVDYNMPVDKEFQKSLDQCAASLEERSSAPYALQRAVDWELKMFYSLEDELSEWFCSSDYMHFGQTQTLFKQKITQPQLFFDDENYAASVVECLIEDIPNSLASNLLALSYISMGCFAFTNSKSEHTKIIRRNNLMLVPHIQEIVHAFKKIAISCRDDNRNLKKQTILLFHSSTILYFICSICIEGRGENPEAVNVVIDAFEKTDLLEFLTKYIENWRWNSRLAMRIRNMISLLFKLIVLQFGDSSVYKQTKSSIYNLHGLTYPSKHPEKLSISPLHYQAFREDITSRFPDYNMPSSGLPKDVDKSESLSQFLEIPRPKSKNPLNMALIVPEKHIATPAPSPPSSPQLMHLGEGPRPRKSFQTNMAYPCLYPSDNEGSEDDTLEDRIDLNIERKPDNDIVIPFSTEEAARILSESLEIKLSTKQLWYERDLFMITERGWKQQLENEPYDYAALNHDANSSKEEKSAICIMQRIDKYYKSCLSSFNSLVFVLLQTMESSLTNNFHRKSEVSDKNLLNMLTPQLEIVRAKELSLKSAAGILHALLKWFKLSHILKFEHLAVVIHDSRYINTCASILSKYSEVYPERVFNKYVQTPNSFWKECSLSNESYRESYSVDDSGEVDTEIMPSFAYLLRILRKVTGNKTQRLKELPLSIGILFKRYYRLFNLDMYHPILKITRELTPFKNKRWKSEHMELISGVYLYEKLELTDNWVTGKDISGELSDACGQEIALRALLQFYNFQHYEISMEDLGYGHRNSSSQDLLNKESEYLNI", "length": 953 }, "evidence": [ { "id": "MGI:2444363", "url": "https://alliancegenome.org/gene/MGI:2444363#orthology", "database": "AGR" }, { "id": "HGNC:22209", "url": "https://alliancegenome.org/gene/HGNC:22209#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120328-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120328-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0035437", "url": "https://alliancegenome.org/gene/FB:FBgn0035437#orthology", "database": "AGR" }, { "id": "RGD:1588437", "url": "https://alliancegenome.org/gene/RGD:1588437#orthology", "database": "AGR" }, { "id": "SGD:S000005071", "url": "https://alliancegenome.org/gene/SGD:S000005071#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5VSL9-1", "protein_name": "Striatin-interacting protein 1", "gene_name": "STRIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPAVGGPGPLIVNNKQPQPPPPPPPAAAQPPPGAPRAAAGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELSELYSYTEGPEFLMNRKCFEEDFRIHVTDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQSWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQECEGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRSILGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDNSLEGETFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVHELPELTAESLEAGDSNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRAHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "length": 837 }, "evidence": [ { "id": "FB:FBgn0035437", "url": "https://alliancegenome.org/gene/FB:FBgn0035437#orthology", "database": "AGR" }, { "id": "SGD:S000005071", "url": "https://alliancegenome.org/gene/SGD:S000005071#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q803T2-1", "protein_name": "Striatin-interacting protein 1 homolog", "gene_name": "strip1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDGVGLCANNKQKQNQMLPNKMRGEFTRNQRKDSEGLSEAPDLEFEYSDADKWTAELSELYSYTEGPEFLLNRKCFEEDFHTHLPDQKWTELDSVQRRAHAMRLLDGLEVIGRERRLKVARAILYMAQGTFGECSSELEVQHWMRYNVFLLLDVGAFTALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLMVETIQREEPTDSPEWRTIRETFKSELGSPLYNHEPVSVMLFGMVTKFCSGHAPHFPMKKVLLLLWKTILFTLGGFEQLQSCKISRRAALGLPPLPEDSIRVVRSMRAASPPASASDLIEQQQRRARREHKALIKQDNLDTFNEKDPYKADDSHEDEEENDDNDNSLEAEPFPLERDEVMPPPIPHPPTERMCFPKGLPWAPKVREKDIESFLESSRSKFIGYTLGNDTDTVVGLPRPIHESIKTLKQHKYVSIAEVQIAKEEAFQKTPLSGGEEELELCATELLYQGILPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEIIVKAISAILLLLLKHFKLNHVYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISALDFPHCVIHELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKGNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNSRRYDKNQSNPEFLPVDNCLQSVLGQRIDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "length": 813 }, "evidence": [ { "id": "FB:FBgn0035437", "url": "https://alliancegenome.org/gene/FB:FBgn0035437#orthology", "database": "AGR" }, { "id": "SGD:S000005071", "url": "https://alliancegenome.org/gene/SGD:S000005071#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8C079-1", "protein_name": "Striatin-interacting protein 1", "gene_name": "Strip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPAAAGPGPLIVNNKQPQPPPPPPPATAQPPPGAPRAAGGLLPGGKAREFNRNQRKDSEGYSESPDLEFEYADTDKWAAELAELYSYTEGPEFLMNRKCFEEDFRIHVSDKKWTELDTNQHRTHAMRLLDGLEVTAREKRLKVARAILYVAQGTFGECSSEAEVQFWMRYNIFLLLEVGTFNALVELLNMEIDNSAACSSAVRKPAISLADSTDLRVLLNIMYLIVETVHQDCDGDKAEWRTMRQTFRAELGSPLYNNEPFAIMLFGMVTKFCSGHAPHFPMKKVLLLLWKTVLCTLGGFEELQSMKAEKRTLLGLPPLPEDSIKVIRNMRAASPPASASDLIEQQQKRGRREHKALIKQDNLDAFNERDPYKADDSREEEEENDDDSSLEGEAFPLERDEVMPPPLQHPQTDRLTCPKGLPWAPKVREKDIEMFLESSRSKFIGYTLGSDTNTVVGLPRPIHESIKTLKQHKYTSIAEVQAQMEEEYLRSPLSGGEEEVEQVPAETLYQGLLPSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPTTVLQSMKLGVDVNRHKEVIVKAISAVLLLLLKHFKLNHIYQFEYMAQHLVFANCIPLILKFFNQNIMSYITAKNSISVLDYPHCVVNELPELTAESLEAGDNNQFCWRNLFSCINLLRILNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMMQLYVLKLLKVQTKYLGRQWRKSNMKTMSAIYQKVRHRLNDDWAYGNDLDARPWDFQAEECALRANIERFNARRYDRTHSNPDFLPVDNCLQSVLGQRVDLPEDFQMNYDLWLEREVFSKPISWEELLQ", "length": 837 }, "evidence": [ { "id": "FB:FBgn0035437", "url": "https://alliancegenome.org/gene/FB:FBgn0035437#orthology", "database": "AGR" }, { "id": "SGD:S000005071", "url": "https://alliancegenome.org/gene/SGD:S000005071#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C9H6-1", "protein_name": "Striatin-interacting proteins 2", "gene_name": "Strip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDPAAPGPAGSPANDNGNGNGNGNGNGNGGKGKPAVPKGRETFRNQRRESEGSVDCPTLEFEYGDSDGHAAELSELYSYTENLEFTTNRKCFEEDFRTQVQDTKEWLELEEDAQKTYVMGLLDRLEVVSREKRLKVARAVLYLAQGTFGECDSEVDVLHWSRYNCFLLYQMGTFSAFLELLHMEIDNSQASSSALRKPAVSIADSTELRVLLSVMYLMVENIRLEREIDPCGWRTARETFRTELSFSTHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQALKIQKRAELGLPPLAEDSIQVVKSMRAASPPSYTLDLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESAADGERTLDGELDLLEQDPLVPPPPSQTPLSTDRVAFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADIQIKNEEELEKCPLSLGEEVVPETPSEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPVTVLQSMKLGIDVNRHKEIIVKSISALLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAGDNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKIQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDKPQDSEFSPVDNCLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "length": 844 }, "evidence": [ { "id": "MGI:2444363", "url": "https://alliancegenome.org/gene/MGI:2444363#orthology", "database": "AGR" }, { "id": "HGNC:22209", "url": "https://alliancegenome.org/gene/HGNC:22209#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120328-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120328-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0035437", "url": "https://alliancegenome.org/gene/FB:FBgn0035437#orthology", "database": "AGR" }, { "id": "RGD:1588437", "url": "https://alliancegenome.org/gene/RGD:1588437#orthology", "database": "AGR" }, { "id": "SGD:S000005071", "url": "https://alliancegenome.org/gene/SGD:S000005071#orthology", "database": "AGR" }, { "id": "A0A8M9PI62", "url": "https://omabrowser.org/oma/group/A0A8M9PI62/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IRD5-1", "protein_name": "Striatin interacting protein, isoform B", "gene_name": "Strip", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKQKNKLLFDTCKNQLSCGAVNARSSMMQSIQSRINVLNTIAASSKRIERASVDTDTHDADANCDGPDLDFVYADVDGYQNEIAELYSYTEFSEFQMNVKAFEDQMELYDLPPNWQKQDSASQRGIVMKLVDQLEVSDRSFRMQAARCILYLAQGCWAEVQSDEEQHQITRDNVLVLYQLGVFASFIDLLNMEIESACSPDIVAVKITNVTLVDSTDIRVILSVLYIITETIRDEKEKGSEDYRELADSFVQEINSPLPDGELLAVKLLGMITRFCSGAAPQFPMKKVVLLLWKVSLLGLGGMDVLKNLKNEYRLKVGLEPITEDTLEVTKCMRASSPPATATDILENQYPKRNFKRSLMKQRFLDEPEQIDMEMGGNEGQNNANNGSGNGGNGEEELSQYYRPYDDPSSSASTTSTANPNNQPSLTQPPAAVPPVQITARLPWTPKVRQKDIDQFLDISRNKFIGYSLIGDHESLAGLPQPIHEGFKTLQRHMYMSLADVQIKKEEDIARNPISTHEDEIKLTPAEVLYQAILPNLPQYMIALLKVLLAASPTSKSKTESINIMADVLPRKMPLTATQSTKLTVDIGRHKEIIVKAVSAIILLYLKHFKINHVYQFEFMSQHLVFANCIPLVLKFFNQTITEYVNTKNSIPLLDFPSCVIGEQPDLSGDSFVYGGEMSDKSYSWRNVFSCINLLRILNKLIKWKHSRVMMLVVFKSAPILKKTLKVRHAMMQLYVLKLLKMQTKYLGRQWRKSNMKTMSAIYAKVRHRLNDDWAFGNDLESRPWDFQAEECTLRACVDRFNLRRYPEATQKCGNNGTAAQNAENAQQSNMMAGNNGCGNNGDANGYGNNGGGGNGGHNQQQQLNDYGVEGGFPSDEILTHSDFAFFGHSGWWDRKVELTDYFKANYAVWLEEEVYNSQTDWDAL", "length": 927 }, "evidence": [ { "id": "MGI:2444363", "url": "https://alliancegenome.org/gene/MGI:2444363#orthology", "database": "AGR" }, { "id": "HGNC:22209", "url": "https://alliancegenome.org/gene/HGNC:22209#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120328-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120328-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0035437", "url": "https://alliancegenome.org/gene/FB:FBgn0035437#orthology", "database": "AGR" }, { "id": "RGD:1588437", "url": "https://alliancegenome.org/gene/RGD:1588437#orthology", "database": "AGR" }, { "id": "SGD:S000005071", "url": "https://alliancegenome.org/gene/SGD:S000005071#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9ULQ0-1", "protein_name": "Striatin-interacting protein 2", "gene_name": "STRIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDPAAPGTGGPPANGNGNGGGKGKQAAPKGREAFRSQRRESEGSVDCPTLEFEYGDADGHAAELSELYSYTENLEFTNNRRCFEEDFKTQVQGKEWLELEEDAQKAYIMGLLDRLEVVSRERRLKVARAVLYLAQGTFGECDSEVDVLHWSRYNCFLLYQMGTFSTFLELLHMEIDNSQACSSALRKPAVSIADSTELRVLLSVMYLMVENIRLERETDPCGWRTARETFRTELSFSMHNEEPFALLLFSMVTKFCSGLAPHFPIKKVLLLLWKVVMFTLGGFEHLQTLKVQKRAELGLPPLAEDSIQVVKSMRAASPPSYTLDLGESQLAPPPSKLRGRRGSRRQLLTKQDSLDIYNERDLFKTEEPATEEEEESAGDGERTLDGELDLLEQDPLVPPPPSQAPLSAERVAFPKGLPWAPKVRQKDIEHFLEMSRNKFIGFTLGQDTDTLVGLPRPIHESVKTLKQHKYISIADVQIKNEEELEKCPMSLGEEVVPETPCEILYQGMLYSLPQYMIALLKILLAAAPTSKAKTDSINILADVLPEEMPITVLQSMKLGIDVNRHKEIIVKSISTLLLLLLKHFKLNHIYQFEYVSQHLVFANCIPLILKFFNQNILSYITAKNSISVLDYPCCTIQDLPELTTESLEAGDNSQFCWRNLFSCINLLRLLNKLTKWKHSRTMMLVVFKSAPILKRALKVKQAMLQLYVLKLLKLQTKYLGRQWRKSNMKTMSAIYQKVRHRMNDDWAYGNDIDARPWDFQAEECTLRANIEAFNSRRYDRPQDSEFSPVDNCLQSVLGQRLDLPEDFHYSYELWLEREVFSQPICWEELLQNH", "length": 834 }, "evidence": [ { "id": "MGI:2444363", "url": "https://alliancegenome.org/gene/MGI:2444363#orthology", "database": "AGR" }, { "id": "HGNC:22209", "url": "https://alliancegenome.org/gene/HGNC:22209#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120328-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120328-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0035437", "url": "https://alliancegenome.org/gene/FB:FBgn0035437#orthology", "database": "AGR" }, { "id": "RGD:1588437", "url": "https://alliancegenome.org/gene/RGD:1588437#orthology", "database": "AGR" }, { "id": "SGD:S000005071", "url": "https://alliancegenome.org/gene/SGD:S000005071#orthology", "database": "AGR" }, { "id": "A0A8M9PI62", "url": "https://omabrowser.org/oma/group/A0A8M9PI62/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of cardiac muscle contraction", "id": "GO:0055117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055117", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PI62", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PI62", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62" } ], "pmid": "" }, { "name": "negative regulation of hippo signaling", "id": "GO:0035331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035331", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PI62", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PI62", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62" } ], "pmid": "" }, { "name": "FAR/SIN/STRIPAK complex", "id": "GO:0090443", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090443", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PI62", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PI62", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62" }, { "id": "SM01293", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01293" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Far11/STRP C-terminal", "eco_id": "ECO_0000259", "start_pos": 461, "end_pos": 817, "start_aa": "Pro", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PI62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI62" }, { "id": "SM01292", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01292" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Far11/STRP N-terminal", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 361, "start_aa": "Ser", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. 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"uniprot_ac": "A0A8M6Z906", "uniprot_id": "A0A8M6Z906_DANRE", "mass": { "chemical_mass": 103588.0, "monoisotopic_mass": 103588.0 }, "refseq": { "ac": "XP_017213661", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213661" }, "gene_names": [ { "name": "itih3b.2", "type": "recommended", "evidence": [ { "id": "A0A8M6Z906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906" } ] }, { "name": "itih3b.2", "type": "synonym", "evidence": [ { "id": "XP_017213661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213661" } ] }, { "name": "si:ch211-210k13.1", "type": "synonym", "evidence": [ { "id": "XP_017213661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213661" }, { "id": "A0A8M6Z906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906" } ] }, { "name": "wu:fj67a04", "type": "synonym", "evidence": [ { "id": "XP_017213661", 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Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017213661.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213661" } ] } ], "disease": [ { "disease_id": "DOID:2957", "recommended_name": { "id": "DOID:2957", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2957", "name": "pulmonary tuberculosis", "description": "A tuberculosis that is a contagious disease located_in lungs. The infection has_symptom fever, has_symptom cough, has_symptom difficulty in breathing, has_symptom inflammatory infiltrations, has_symptom formation of tubercles, has_symptom caseation, has_symptom pleural effusion, and has_symptom fibrosis." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "2957", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2957" } ] }, { "disease_id": "DOID:332", "recommended_name": { "id": "DOID:332", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:332", "name": "amyotrophic lateral sclerosis", "description": "A motor neuron disease that is characterized by muscle spasticity, rapidly progressive weakness due to muscle atrophy, difficulty in speaking, swallowing, and breathing." }, "synonyms": [ { "id": "DOID:332", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:332", "name": "ALS", "description": "" }, { "id": "DOID:332", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:332", "name": "Lou Gehrig's disease", "description": "" }, { "id": "DOID:332", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:332", "name": "motor neuron disease, bulbar", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis type 1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "ALS1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis type 1", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "FALS", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1, autosomal dominant amyotrophic lateral sclerosis 1, autosomal recessive, included", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis 1, familial", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, autosomal dominant", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, familial", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, sporadic", "description": "" }, { "id": "MONDO:0007103", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007103", "name": "amyotrophic lateral sclerosis, sporadic, included", "description": "" }, { "id": "MIM:105400", "resource": "MIM", "url": "https://www.omim.org/entry/105400", "name": "Amyotrophic lateral sclerosis 1", "description": "Amyotrophic lateral sclerosis 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "332", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:332" } ] }, { "disease_id": "DOID:5082", "recommended_name": { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "liver cirrhosis", "description": "" }, "synonyms": [ { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "Cirrhosis", "description": "" }, { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "cirrhosis of liver", "description": "" }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis of liver", "description": "A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy." }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:684", "recommended_name": { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver." }, "synonyms": [ { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "Hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MIM:114550", "resource": "MIM", "url": "https://www.omim.org/entry/114550", "name": "Hepatocellular carcinoma", "description": "Hepatocellular carcinoma" } ], "unlinked_id_list": [], "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ] }, { "disease_id": "DOID:8805", "recommended_name": { "id": "DOID:8805", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8805", "name": "intermediate coronary syndrome", "description": "" }, "synonyms": [ { "id": "DOID:8805", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8805", "name": "Angina at rest", "description": "" }, { "id": "DOID:8805", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8805", "name": "Anginal chest pain at rest", "description": "" }, { "id": "DOID:8805", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8805", "name": "Impending infarction", "description": "" }, { "id": "DOID:8805", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8805", "name": "Preinfarction angina", "description": "" }, { "id": "DOID:8805", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8805", "name": "Unstable angina", "description": "" }, { "id": "DOID:8805", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8805", "name": "Worsening angina", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8805", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8805" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z906", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "itih3b.2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050626-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050626-133", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z906", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z906", "database": "AlphaFoldDB", "categories": [] }, { "id": "100003906", "url": "https://www.ncbi.nlm.nih.gov/gene/100003906", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050934", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050934", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100003906", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003906", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z367", "url": "https://www.orthodb.org/?gene=A0A8M6Z367", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z8L4", "url": "https://www.orthodb.org/?gene=A0A8M6Z8L4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z906", "url": "https://www.orthodb.org/?gene=A0A8M6Z906", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10338", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10338", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10338:SF119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10338:SF119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213661", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M1N6Z1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N6Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1N6Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N6Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z367", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z367", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z367-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z367-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8L4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z906", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z906-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PUM4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PUM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PUM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PUM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q6Z2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q6Z2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q6Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q6Z2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13AAH8", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13AAH8-1", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GNW4", "url": "https://www.uniprot.org/uniprotkb/A0AC58GNW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GNW4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GNW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GNX5", "url": "https://www.uniprot.org/uniprotkb/A0AC58GNX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GNX5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GNX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GNX9", "url": "https://www.uniprot.org/uniprotkb/A0AC58GNX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GNX9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GNX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050626-133", "url": "https://zfin.org/ZDB-GENE-050626-133", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVMMDRVAFRLILFGAFLISATSAPVEKKQNVDIYSFYINSTVSSRYATTIITSRVANKLSEPQEIQFEVKIPKNAFISKFRMIIEGKTYDGVVKKKEEAQQQYNKAVSRGESAGLIKSVGRTLEDFKTSVTVAANSKVTFELTYEELLKRRLGKYELLINAQPMQPVADFKIDVHIQENPGISFLEVKGDLNTGDLASAVKTTRADKDAWVTFYPTRDQQTKCTNCAENGLNGDLIITYDVNRGNPKGEVQISNGYFVHYFAPSDVPRIPKNVVFIIDRSGSMHGRKIRQTRSALLTILNDLDEDDHFGLITFDAEIDFWKRELLQATKANRENAESFVKRIQDRGATNINDAVLAGVDMINRNPRKGTASILILLTDGDPTAGETNIEKIMANVKEAIGSKFPLYCLGFGYDVNFDFLTKMSLENNAVARRIYEDSDADIQLQGFYDEVAVPLLTDIQLSYAGGKHLTKSSFGLYFNGSEIVVSGQITDNSVETFTTEVIAVSKGNNVMYQDTVMMKDASDVKPENEDFMQRLWAYLTVKQLLERQVLLKGKEQEDEKEEALQLSLKYQFVTPLTSMVVTKPQEGEVDVADKPKEGGESPRYPASQPRLVPYGRSGTPGFSHHHYITTSRQPGLHALPGLPGPPGPPDASINYARHPGGSHRAFLQEASVVPKDTFSFLGFDQHDVVAHSDLLLSSAVILPTHMPRRTLPKATSVAGLVPVSRFLLPAVGQSKPLCFDVPVPNKLKLLEDSASEFSMNGESTHRHNGFRRIALHYKSNHDLVIDKRSIKYNDGQNNVEFLWDQELTQHNAEGVSLILQSNELDITMGNIRIVVLLHKINGQVFLWPAVRQQPKDVVLAGILGKSDASYDEIQGSQPPSLKINNQEVKADLEDVKDYRLLSAPVIRCWLVSFQAVMKGDVSDFTVTKM", "length": 929, "header": "tr|A0A8M6Z906-1|A0A8M6Z906_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=itih3b.2 PE=1 SV=2 CANONICAL=A0A8M6Z906-1" }, "isoforms": [ { "isoform_ac": "A0A8M1N6Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906/entry#A0A8M1N6Z1-1", "sequence": { "sequence": "MDRVAFRLILFGAFLISATSAPVEKKQNVDIYSFYINSTVSSRYATTIITSRVANKLSEPQEIQFEVKIPKNAFISKFRMIIEGKTYDGVVKKKEEAQQQYNKAVSRGESAGLIKSVGRTLEDFKTSVTVAANSKVTFELTYEELLKRRLGKYELLINAQPMQPVADFKIDVHIQESPGISFLEVKGDLNTGDLASAVKTKRADKDAWVTFYPTRDQQTKCTNCAENGLNGDLIITYDVNRGNPKGEVQISNGYFVHYFAPSDVPRIPKNVVFIIDRSGSMHGRKIRQTRSALLTILNDLDEDDHFGLITFDAEIDFWKRELLQATKANRENAESFVKRIQDRGATNINDAVLAGVDMINRNPRKGTASILILLTDGDPTAGETNIEKIMANVKEAIGSKFPLYCLGFGYDVNFDFLTKMSLENNAVARRIYEDSDADIQLQGFYDEVAVPLLTDIQLSYAGGKHLTKSSFGLYFNGSEIVVSGQITDNSVETFTTEVIAVSKGNNVMYQDTVMMKDASDVKPENEDFMQRLWAYLTVKQLLERQVLLKGKEQEDEKEQALQLSLKYQFVTPLTSMVVTKPQEGEVDVADKPKEGGESPRYPASQPRLVPYGRSGTPGFSHHHYTTNSGQPGLHALPGLPGPPGPPDASISYGRFSGGSHRAFLQEGFFDQHDVVAHSDLLLSSAVILPTHMPRRTLPKATSVAGLVPVSRFLLPAVGQSKPLCFDVPVPNKLKLLEDSASEFSMNGESTHRHNGFRRIALHYKSNHDLVIDKRSIKYNDGQNNVEFLWDQELTQHNAEGVSLILQSNELDITMGNIRIVVLLHKINGQVFLWPAVRQQPKDVVLAGILGKSDASYDEIQGSQPPSLKINNQEVKADLEDVKDYRLLSAPVIRCWLVSFQAVMKGDVSDFTVTKM", "length": 915, "header": "tr|A0A8M1N6Z1-1|A0A8M6Z906_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=itih3b.2 PE=1 SV=1 CANONICAL=A0A8M6Z906-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z367-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906/entry#A0A8M6Z367-1", "sequence": { "sequence": "MVMMDRVAFRLILFGAFLISATSAPVEKKQNVDIYSFYINSTVSSRYATTIITSRVANKLSEPQEIQFEVKIPKNAFISKFRMIIEGKTYDGVVKKKEEAQQQYNKAVSRGESAGLIKSVGRTLEDFKTSVTVAANSKVTFELTYEELLKRRLGKYELLINAQPMQPVADFKIDVHIQENPGISFLEVKGDLNTGDLASAVKTTRADKDAWVTFYPTRDQQTKCTNCAENGLNGDLIITYDVNRGNPKGEVQISNGYFVHYFAPSDVPRIPKNVVFIIDRSGSMHGRKIRQTRSALLTILNDLDEDDHFGLITFDAEIDFWKRELLQATKANRENAESFVKRIQDRGATNINDAVLAGVDMINRNPRKGTASILILLTDGDPTAGETNIEKIMANVKEAIGSKFPLYCLGFGYDVNFDFLTKMSLENNAVARRIYEDSDADIQLQGFYDEVAVPLLTDIQLSYAGGKHLTKSSFGLYFNGSEIVVSGQITDNSVETFTTEVIAVSKGNNVMYQDTVMMKDASDVKPENEDFMQRLWAYLTVKQLLERQVLLKGKEQEDEKEEALQLSLKYQFVTPLTSMVVTKPQEGEVDVADKPKEGGESPRYPASQPRLVPYGRSGTPGFSHHHYITTSRQPGLHALPGLPGPPGPPDASINYARHPGGSHRAFLQEASVVPKGFDQHDLLLSSAVILPTHMPRRTLPKATSVAGLVPVSRFLLPAVGQSKPLCFDVPVPNKLKLLEDSASEFSMNGESTHRHNGFRRIALHYKSNHDLVIDKRSIKYNDGQNNVEFLWDQELTQHNAEGVSLILQSNELDITMGNIRIVVLLHKINGQVFLWPAVRQQPKDVVLAGILGKSDASYDEIQGSQPPSLKINNQEVKADLEDVKDYRLLSAPVIRCWLVSFQAVMKGDVSDFTVTKM", "length": 917, "header": "tr|A0A8M6Z367-1|A0A8M6Z367_DANRE Computationally mapped isoform of Uncharacterized protein isoform X5 OS=Danio rerio OX=7955 GN=itih3b.2 PE=1 SV=2 CANONICAL=A0A8M6Z906-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z8L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906/entry#A0A8M6Z8L4-1", "sequence": { "sequence": "MVMMDRVAFRLILFGAFLISATSAPVEKKQNVDIYSFYINSTVSSRYATTIITSRVANKLSEPQEIQFEVKIPKNAFISKFRMIIEGKTYDGVVKKKEEAQQQYNKAVSRGESAGLIKSVGRTLEDFKTSVTVAANSKVTFELTYEELLKRRLGKYELLINAQPMQPVADFKIDVHIQENPGISFLEVKGDLNTGDLASAVKTTRADKDAWVTFYPTRDQQTKCTNCAENGLNGDLIITYDVNRGNPKGEVQISNGYFVHYFAPSDVPRIPKNVVFIIDRSGSMHGRKIRQTRSALLTILNDLDEDDHFGLITFDAEIDFWKRELLQATKANRENAESFVKRIQDRGATNINDAVLAGVDMINRNPRKGTASILILLTDGDPTAGETNIEKIMANVKEAIGSKFPLYCLGFGYDVNFDFLTKMSLENNAVARRIYEDSDADIQLQGFYDEVAVPLLTDIQLSYAGGKHLTKSSFGLYFNGSEIVVSGQITDNSVETFTTEVIAVSKGNNVMYQDTVMMKDASDVKPENEDFMQRLWAYLTVKQLLERQVLLKGKEQEDEKEEALQLSLKYQFVTPLTSMVVTKPQEGEVDVADKPKEGGESPRYPASQPRLVPYGRSGTPGFSHHHYITTSRQPGLHALPGLPGPPGPPDASINYARHPGGSHRAFLQEASVVPKDTFSFLGFDQHDLLLSSAVILPTHMPRRTLPKATSVAGLVPVSRFLLPAVGQSKPLCFDVPVPNKLKLLEDSASEFSMNGESTHRHNGFRRIALHYKSNHDLVIDKRSIKYNDGQNNVEFLWDQELTQHNAEGVSLILQSNELDITMGNIRIVVLLHKINGQVFLWPAVRQQPKDVVLAGILGKSDASYDEIQGSQPPSLKINNQEVKADLEDVKDYRLLSAPVIRCWLVSFQAVMKGDVSDFTVTKM", "length": 923, "header": "tr|A0A8M6Z8L4-1|A0A8M6Z8L4_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=itih3b.2 PE=1 SV=2 CANONICAL=A0A8M6Z906-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z906-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906/entry#A0A8M6Z906-1", "sequence": { "sequence": "MVMMDRVAFRLILFGAFLISATSAPVEKKQNVDIYSFYINSTVSSRYATTIITSRVANKLSEPQEIQFEVKIPKNAFISKFRMIIEGKTYDGVVKKKEEAQQQYNKAVSRGESAGLIKSVGRTLEDFKTSVTVAANSKVTFELTYEELLKRRLGKYELLINAQPMQPVADFKIDVHIQENPGISFLEVKGDLNTGDLASAVKTTRADKDAWVTFYPTRDQQTKCTNCAENGLNGDLIITYDVNRGNPKGEVQISNGYFVHYFAPSDVPRIPKNVVFIIDRSGSMHGRKIRQTRSALLTILNDLDEDDHFGLITFDAEIDFWKRELLQATKANRENAESFVKRIQDRGATNINDAVLAGVDMINRNPRKGTASILILLTDGDPTAGETNIEKIMANVKEAIGSKFPLYCLGFGYDVNFDFLTKMSLENNAVARRIYEDSDADIQLQGFYDEVAVPLLTDIQLSYAGGKHLTKSSFGLYFNGSEIVVSGQITDNSVETFTTEVIAVSKGNNVMYQDTVMMKDASDVKPENEDFMQRLWAYLTVKQLLERQVLLKGKEQEDEKEEALQLSLKYQFVTPLTSMVVTKPQEGEVDVADKPKEGGESPRYPASQPRLVPYGRSGTPGFSHHHYITTSRQPGLHALPGLPGPPGPPDASINYARHPGGSHRAFLQEASVVPKDTFSFLGFDQHDVVAHSDLLLSSAVILPTHMPRRTLPKATSVAGLVPVSRFLLPAVGQSKPLCFDVPVPNKLKLLEDSASEFSMNGESTHRHNGFRRIALHYKSNHDLVIDKRSIKYNDGQNNVEFLWDQELTQHNAEGVSLILQSNELDITMGNIRIVVLLHKINGQVFLWPAVRQQPKDVVLAGILGKSDASYDEIQGSQPPSLKINNQEVKADLEDVKDYRLLSAPVIRCWLVSFQAVMKGDVSDFTVTKM", "length": 929, "header": "tr|A0A8M6Z906-1|A0A8M6Z906_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=itih3b.2 PE=1 SV=2 CANONICAL=A0A8M6Z906-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PUM4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906/entry#A0A8M9PUM4-1", "sequence": { "sequence": "MVMMDRVAFRLILFGAFLISATSAPVEKKQNVDIYSFYINSTVSSRYATTIITSRVANKLSEPQEIQFEVKIPKNAFISKFRMIIEGKTYDGVVKKKEEAQQQYNKAVSRGESAGLIKSVGRTLEDFKTSVTVAANSKVTFELTYEELLKRRLGKYELLINAQPMQPVADFKIDVHIQENPGISFLEVKGDLNTGDLASAVKTTRADKDAWVTFYPTRDQQTKCTNCAENGLNGDLIITYDVNRGNPKGEVQISNGYFVHYFAPSDVPRIPKNVVFIIDRSGSMHGRKIRQTRSALLTILNDLDEDDHFGLITFDAEIDFWKRELLQATKANRENAESFVKRIQDRGATNINDAVLAGVDMINRNPRKGTASILILLTDGDPTAGETNIEKIMANVKEAIGSKFPLYCLGFGYDVNFDFLTKMSLENNAVARRIYEDSDADIQLQGFYDEVAVPLLTDIQLSYAGGKHLTKSSFGLYFNGSEIVVSGQITDNSVETFTTEVIAVSKGNNVMYQDTVMMKDASDVKPENEDFMQRLWAYLTVKQLLERQVLLKGKEQEDEKEEALQLSLKYQFVTPLTSMVVTKPQEGEVDVADKPKEGGESPRYPAPGFSHHHYITTSRQPGLHALPGLPGPPGPPDASINYARHPGGSHRAFLQEASVVPKDTFSFLGFDQHDVVAHSDLLLSSAVILPTHMPRRTLPKATSVAGLVPVSRFLLPAVGQSKPLCFDVPVPNKLKLLEDSASEFSMNGESTHRHNGFRRIALHYKSNHDLVIDKRSIKYNDGQNNVEFLWDQELTQHNAEGVSLILQSNELDITMGNIRIVVLLHKINGQVFLWPAVRQQPKDVVLAGILGKSDASYDEIQGSQPPSLKINNQEVKADLEDVKDYRLLSAPVIRCWLVSFQAVMKGDVSDFTVTKM", "length": 916, "header": "tr|A0A8M9PUM4-1|A0A8M6Z906_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=itih3b.2 PE=1 SV=2 CANONICAL=A0A8M6Z906-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q6Z2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906/entry#A0A8M9Q6Z2-1", "sequence": { "sequence": "MVMMDRVAFRLILFGAFLISATSAPVEKKQNVDIYSFYINSTVSSRYATTIITSRVANKLSEPQEIQFEVKIPKNAFISKFRMIIEGKTYDGVVKKKEEAQQQYNKAVSRGESAGLIKSVGRTLEDFKTSVTVAANSKVTFELTYEELLKRRLGKYELLINAQPMQPVADFKIDVHIQENPGISFLEVKGDLNTGDLASAVKTTRADKDAWVTFYPTRDQQTKCTNCAENGLNGDLIITYDVNRGNPKGEVQISNGYFVHYFAPSDVPRIPKNVVFIIDRSGSMHGRKIRQTRSALLTILNDLDEDDHFGLITFDAEIDFWKRELLQATKANRENAESFVKRIQDRGATNINDAVLAGVDMINRNPRKGTASILILLTDGDPTAGETNIEKIMANVKEAIGSKFPLYCLGFGYDVNFDFLTKMSLENNAVARRIYEDSDADIQLQGFYDEVAVPLLTDIQLSYAGGKHLTKSSFGLYFNGSEIVVSGQITDNSVETFTTEVIAVSKGNNVMYQDTVMMKDASDVKPENEDFMQRLWAYLTVKQLLERQVLLKGKEQEDEKEEALQLSLKYQFVTPLTSMVVTKPQEGEVDVADKPKEGGESPRYPASQPRLVPYGRSGTPGFSHHHYITTSRQPGLHALPGLPGPPGPPDASINYARHPGGSHRAFLQEGFDQHDLLLSSAVILPTHMPRRTLPKATSVAGLVPVSRFLLPAVGQSKPLCFDVPVPNKLKLLEDSASEFSMNGESTHRHNGFRRIALHYKSNHDLVIDKRSIKYNDGQNNVEFLWDQELTQHNAEGVSLILQSNELDITMGNIRIVVLLHKINGQVFLWPAVRQQPKDVVLAGILGKSDASYDEIQGSQPPSLKINNQEVKADLEDVKDYRLLSAPVIRCWLVSFQAVMKGDVSDFTVTKM", "length": 911, "header": "tr|A0A8M9Q6Z2-1|A0A8M6Z906_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=itih3b.2 PE=1 SV=2 CANONICAL=A0A8M6Z906-1" }, "locus": {} }, { "isoform_ac": "A0AB13AAH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906/entry#A0AB13AAH8-1", "sequence": { "sequence": "MDRVAFRLILFGAFLISATSAPVEKKQNVDIYSFYINSTVSSRYATTIITSRVANKLSEPQEIQFEVKIPKNAFISKFRMIIEGKTYDGVVKKKEEAQQQYNKAVSRGESAGLIKSVGRTLEDFKTSVTVAANSKVTFELTYEELLKRRLGKYELLINAQPMQPVADFKIDVHIQESPGISFLEVKGDLNTGDLASAVKTKRADKDAWVTFYPTRDQQTKCTNCAENGLNGDLIITYDVNRGNPKGEVQISNGYFVHYFAPSDVPRIPKNVVFIIDRSGSMHGRKIRQTRSALLTILNDLDEDDHFGLITFDAEIDFWKRELLQATKANRENAESFVKRIQDRGATNINDAVLAGVDMINRNPRKGTASILILLTDGDPTAGETNIEKIMANVKEAIGSKFPLYCLGFGYDVNFDFLTKMSLENNAVARRIYEDSDADIQLQGFYDEVAVPLLTDIQLSYAGGKHLTKSSFGLYFNGSEIVVSGQITDNSVETFTTEVIAVSKGNNVMYQDTVMMKDASDVKPENEDFMQRLWAYLTVKQLLERQVLLKGKEQEDEKEQALQLSLKYQFVTPLTSMVVTKPQEGEVDVADKPKEGGESPRYPASQPRLVPYGRSGTPGFSHHHYTTNSGQPGLHALPGLPGPPGPPDASISYGRFSGGSHRAFLQEASVVPKGFFDQHDVVAHSDLLLSSAVILPTHMPRRTLPKATSVAGLVPVSRFLLPAVGQSKPLCFDVPVPNKLKLLEDSASEFSMNGESTHRHNGFRRIALHYKSNHDLVIDKRSIKYNDGQNNVEFLWDQELTQHNAEGVSLILQSNELDITMGNIRIVVLLHKINGQVFLWPAVRQQPKDVVLAGILGKSDASYDEIQGSQPPSLKINNQEVKADLEDVKDYRLLSAPVIRCWLVSFQAVMKGDVSDFTVTKM", "length": 921, "header": "tr|A0AB13AAH8-1|A0A8M6Z906_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=itih3b.2 PE=1 SV=1 CANONICAL=A0A8M6Z906-1" }, "locus": {} }, { "isoform_ac": "A0AC58GNW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906/entry#A0AC58GNW4-1", "sequence": { "sequence": "MVMMDRVAFRLILFGAFLISATSAPVEKKQNVDIYSFYINSTVSSRYATTIITSRVANKLSEPQEIQFEVKIPKNAFISKFRMIIEGKTYDGVVKKKEEAQQQYNKAVSRGESAGLIKSVGRTLEDFKTSVTVAANSKVTFELTYEELLKRRLGKYELLINAQPMQPVADFKIDVHIQENPGISFLEVKGDLNTGDLASAVKTTRADKDAWVTFYPTRDQQTKCTNCAENGLNGDLIITYDVNRGNPKGEVQISNGYFVHYFAPSDVPRIPKNVVFIIDRSGSMHGRKIRQTRSALLTILNDLDEDDHFGLITFDAEIDFWKRELLQATKANRENAESFVKRIQDRGATNINDAVLAGVDMINRNPRKGTASILILLTDGDPTAGETNIEKIMANVKEAIGSKFPLYCLGFGYDVNFDFLTKMSLENNAVARRIYEDSDADIQLQGFYDEVAVPLLTDIQLSYAGGKHLTKSSFGLYFNGSEIVVSGQITDNSVETFTTEVIAVSKGNNVMYQDTVMMKDASDVKPENEDFMQRLWAYLTVKQLLERQVLLKGKEQEDEKEEALQLSLKYQFVTPLTSMVVTKPQEGEVDVADKPKEGGESPRYPASQPRLVPYGRSGTPGFSHHHYITTSRQPGLHALPGLPGPPGPPDASINYARHPGGSHRAFLQEGFDQHDVVAHSDLLLSSAVILPTHMPRRTLPKATSVAGLVPVSRFLLPAVGQSKPLCFDVPVPNKLKLLEDSASEFSMNGESTHRHNGFRRIALHYKSNHDLVIDKRSIKYNDGQNNVEFLWDQELTQHNAEGVSLILQSNELDITMGNIRIVVLLHKINGQVFLWPAVRQQPKDVVLAGILGKSDASYDEIQGSQPPSLKINNQEVKADLEDVKDYRLLSAPVIRCWLVSFQAVMKGDVSDFTVTKM", "length": 917, "header": "tr|A0AC58GNW4-1|A0AC58GNW4_DANRE Computationally mapped isoform of Uncharacterized protein isoform X4 OS=Danio rerio OX=7955 GN=itih3b.2 PE=1 SV=1 CANONICAL=A0A8M6Z906-1" }, "locus": {} }, { "isoform_ac": "A0AC58GNX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906/entry#A0AC58GNX5-1", "sequence": { "sequence": "MVMMDRVAFRLILFGAFLISATSAPVEKKQNVDIYSFYINSTVSSRYATTIITSRVANKLSEPQEIQFEVKIPKNAFISKFRMIIEGKTYDGVVKKKEEAQQQYNKAVSRGESAGLIKSVGRTLEDFKTSVTVAANSKVTFELTYEELLKRRLGKYELLINAQPMQPVADFKIDVHIQENPGISFLEVKGDLNTGDLASAVKTTRADKDAWVTFYPTRDQQTKCTNCAENGLNGDLIITYDVNRGNPKGEVQISNGYFVHYFAPSDVPRIPKNVVFIIDRSGSMHGRKIRQTRSALLTILNDLDEDDHFGLITFDAEIDFWKRELLQATKANRENAESFVKRIQDRGATNINDAVLAGVDMINRNPRKGTASILILLTDGDPTAGETNIEKIMANVKEAIGSKFPLYCLGFGYDVNFDFLTKMSLENNAVARRIYEDSDADIQLQGFYDEVAVPLLTDIQLSYAGGKHLTKSSFGLYFNGSEIVVSGQITDNSVETFTTEVIAVSKGNNVMYQDTVMMKDASDVKPENEDFMQRLWAYLTVKQLLERQVLLKGKEQEDEKEEALQLSLKYQFVTPLTSMVVTKPQEGEVDVADKPKEGGESPRYPASQPRLVPYGRSGTPGFSHHHYITTSRQPGLHALPGLPGPPGPPDASINYARHPGGSHRAFLQEASVVPKGFDQHDVVAHSDLLLSSAVILPTHMPRRTLPKATSVAGLVPVSRFLLPAVGQSKPLCFDVPVPNKLKLLEDSASEFSMNGESTHRHNGFRRIALHYKSNHDLVIDKRSIKYNDGQNNVEFLWDQELTQHNAEGVSLILQSNELDITMGNIRIVVLLHKINGQVFLWPAVRQQPKDVVLAGILGKSDASYDEIQGSQPPSLKINNQEVKADLEDVKDYRLLSAPVIRCWLVSFQAVMKGDVSDFTVTKM", "length": 923, "header": "tr|A0AC58GNX5-1|A0AC58GNX5_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=itih3b.2 PE=1 SV=1 CANONICAL=A0A8M6Z906-1" }, "locus": {} }, { "isoform_ac": "A0AC58GNX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906/entry#A0AC58GNX9-1", "sequence": { "sequence": "MVMMDRVAFRLILFGAFLISATSAPVEKKQNVDIYSFYINSTVSSRYATTIITSRVANKLSEPQEIQFEVKIPKNAFISKFRMIIEGKTYDGVVKKKEEAQQQYNKAVSRGESAGLIKSVGRTLEDFKTSVTVAANSKVTFELTYEELLKRRLGKYELLINAQPMQPVADFKIDVHIQENPGISFLEVKGDLNTGDLASAVKTTRADKDAWVTFYPTRDQQTKCTNCAENGLNGDLIITYDVNRGNPKGEVQISNGYFVHYFAPSDVPRIPKNVVFIIDRSGSMHGRKIRQTRSALLTILNDLDEDDHFGLITFDAEIDFWKRELLQATKANRENAESFVKRIQDRGATNINDAVLAGVDMINRNPRKGTASILILLTDGDPTAGETNIEKIMANVKEAIGSKFPLYCLGFGYDVNFDFLTKMSLENNAVARRIYEDSDADIQLQGFYDEVAVPLLTDIQLSYAGGKHLTKSSFGLYFNGSEIVVSGQITDNSVETFTTEVIAVSKGNNVMYQDTVMMKDASDVKPENEDFMQRLWAYLTVKQLLERQVLLKGKEQEDEKEEALQLSLKYQFVTPLTSMVVTKPQEGEVDVADKPKEGGESPRYPAPGFSHHHYITTSRQPGLHALPGLPGPPGPPDASINYARHPGGSHRAFLQEASVVPKDTFSFLGFDQHDLLLSSAVILPTHMPRRTLPKATSVAGLVPVSRFLLPAVGQSKPLCFDVPVPNKLKLLEDSASEFSMNGESTHRHNGFRRIALHYKSNHDLVIDKRSIKYNDGQNNVEFLWDQELTQHNAEGVSLILQSNELDITMGNIRIVVLLHKINGQVFLWPAVRQQPKDVVLAGILGKSDASYDEIQGSQPPSLKINNQEVKADLEDVKDYRLLSAPVIRCWLVSFQAVMKGDVSDFTVTKM", "length": 910, "header": "tr|A0AC58GNX9-1|A0AC58GNX9_DANRE Computationally mapped isoform of Uncharacterized protein isoform X8 OS=Danio rerio OX=7955 GN=itih3b.2 PE=1 SV=1 CANONICAL=A0A8M6Z906-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 619, "start_aa": "Thr", "end_pos": 619, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr619", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "A0A8M6Z906", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M6Z906" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan", "glycoprotein_predicted" ], "publication": [ { "title": "HNF factors form a network to regulate liver-enriched genes in zebrafish.", "journal": "Dev. Biol.", "date": "2006", "authors": "Cheng Wei, Guo Lin, Zhang Zhenhai, Soo Hui Meng, Wen Chaoming, Wu Wei, Peng Jinrong", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1N6Z1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N6Z1" } ], "reference": [ { "type": "PubMed", "id": "16631158", "url": "https://glygen.org/publication/PubMed/16631158" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1N6Z1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N6Z1" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Deconvoluting Wavelengths Leading to Fluorescent Light Induced Inflammation and Cellular Stress in Zebrafish (Danio rerio).", "journal": "Sci. Rep.", "date": "2020", "authors": "Boswell Mikki, Boswell William, Lu Yuan, Savage Markita, Walter Ronald B", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1N6Z1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N6Z1" } ], "reference": [ { "type": "PubMed", "id": "32094353", "url": "https://glygen.org/publication/PubMed/32094353" } ] }, { "title": "Unraveling Differential Transcriptomes and Cell Types in Zebrafish Larvae Intestine and Liver.", "journal": "Cells", "date": "2022", "authors": "Gao Yuqi, Jin Qingxia, Gao Ce, Chen Yayue, Sun Zhaoxiang, Guo Guoji, Peng Jinrong", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1N6Z1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N6Z1" } ], "reference": [ { "type": "PubMed", "id": "36291156", "url": "https://glygen.org/publication/PubMed/36291156" } ] }, { "title": "Cdx1b protects intestinal cell fate by repressing signaling networks for liver specification.", "journal": "J. Genet. Genomics", "date": "2022", "authors": "Jin Qingxia, Gao Yuqi, Shuai Shimin, Chen Yayue, Wang Kaiyuan, Chen Jun, Peng Jinrong, Gao Ce", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1N6Z1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N6Z1" } ], "reference": [ { "type": "PubMed", "id": "36460297", "url": "https://glygen.org/publication/PubMed/36460297" } ] }, { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0A8M6Z906", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M6Z906" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:100003906", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003906", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6X935-1", "protein_name": "Inter alpha-trypsin inhibitor, heavy chain 4", "gene_name": "Itih4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSPAPAHMWNLVLFLPSLLAVLPTTTAEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRADAVQEATFQVELPRKAFITNFSMIIDGVTYPGVVKEKAEAQKQYSAAVGRGESAGIVKTTGRQTEKFEVSVNVAPGSKITFELIYQELLQRRLGMYELLLKVRPQQLVKHLQMDIYIFEPQGISILETESTFMTPELANALTTSQNKTKAHIRFKPTLSQQQKSQSEQDTVLNGDFIVRYDVNRSDSGGSIQIEEGYFVHHFAPENLPTMSKNVIFVIDKSGSMSGKKIQQTREALVKILKDLSPQDQFNLIEFSGEANQWKQSLVQATEENLNKAVNYASRIRAHGGTNINNAVLLAVELLDRSNQAELLPSKSVSLIILLTDGDPTVGETNPTIIQNNVREAINGQYSLFCLGFGFDVNYPFLEKMALDNGGLARRIYEDSDSALQLQDFYHEVANPLLSSVAFEYPSDAVEEVTRYKFQHHFKGSEMVVAGKLQDQGPDVLLAKVSGQMHMQNITFQTEASVAQQEKEFKSPKYIFHNFMERLWALLTIQQQLEQRISASGAELEALEAQVLNLSLKYNFVTPLTHMVVTKPEGQEQFQVAEKPVEVGDGMQRLPLAAQAHPFRPPVRGSKLMTVLKGSRSQIPRLGDAVRASRQYIPPGFPGPPGPPGFPAPPGPPGFPAPPGPPLASGSDFSLQPSYERMLSLPSVAAQYPADPHLVVTEKSKESTIPEESPNPDHPQVPTITLPLPGSSVDQLCVDILHSEKPMKLFVDPSQGLEVTGKYENTGFSWLEVTIQKPHLQVHATPERLVVTRGRKNTEYKWKKTLFSVLPGLKMTMNMMGLLQLSGPDKVTIGLLSLDDPQRGLMLLLNDTQHFSNNVKGELGQFYRDIVWEPPVEPDNTKRTVKVQGVDYLATRELKLSYQEGFPGAEISCWTVEI", "length": 942 }, "evidence": [ { "id": "HGNC:6169", "url": "https://alliancegenome.org/gene/HGNC:6169#orthology", "database": "AGR" }, { "id": "MGI:109536", "url": "https://alliancegenome.org/gene/MGI:109536#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050626-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050626-133#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14624-1", "protein_name": "Inter-alpha-trypsin inhibitor heavy chain H4", "gene_name": "ITIH4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPPRPVRTCSKVLVLLSLLAIHQTTTAEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRANTVQEATFQMELPKKAFITNFSMIIDGMTYPGIIKEKAEAQAQYSAAVAKGKSAGLVKATGRNMEQFQVSVSVAPNAKITFELVYEELLKRRLGVYELLLKVRPQQLVKHLQMDIHIFEPQGISFLETESTFMTNQLVDALTTWQNKTKAHIRFKPTLSQQQKSPEQQETVLDGNLIIRYDVDRAISGGSIQIENGYFVHYFAPEGLTTMPKNVVFVIDKSGSMSGRKIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRPSLVPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDGDPTVGETNPRSIQNNVREAVSGRYSLFCLGFGFDVSYAFLEKLALDNGGLARRIHEDSDSALQLQDFYQEVANPLLTAVTFEYPSNAVEEVTQNNFRLLFKGSEMVVAGKLQDRGPDVLTATVSGKLPTQNITFQTESSVAEQEAEFQSPKYIFHNFMERLWAYLTIQQLLEQTVSASDADQQALRNQALNLSLAYSFVTPLTSMVVTKPDDQEQSQVAEKPMEGESRNRNVHSGSTFFKYYLQGAKIPKPEASFSPRRGWNRQAGAAGSRMNFRPGVLSSRQLGLPGPPDVPDHAAYHPFRRLAILPASAPPATSNPDPAVSRVMNMKIEETTMTTQTPAPIQAPSAILPLPGQSVERLCVDPRHRQGPVNLLSDPEQGVEVTGQYEREKAGFSWIEVTFKNPLVWVHASPEHVVVTRNRRSSAYKWKETLFSVMPGLKMTMDKTGLLLLSDPDKVTIGLLFWDGRGEGLRLLLRDTDRFSSHVGGTLGQFYQEVLWGSPAASDDGRRTLRVQGNDHSATRERRLDYQEGPPGVEISCWSVEL", "length": 930 }, "evidence": [ { "id": "HGNC:6169", "url": "https://alliancegenome.org/gene/HGNC:6169#orthology", "database": "AGR" }, { "id": "MGI:109536", "url": "https://alliancegenome.org/gene/MGI:109536#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050626-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050626-133#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5EBC0-1", "protein_name": "Inter-alpha-trypsin inhibitor heavy chain 4", "gene_name": "Itih4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKSPAPAHMWNIVLVLLSLLAVLPITTTEKNGIDIYSLTVDSRVSSRFAHTVVTSRVVNRADTVQEATFQVELPRKAFITNFSMIIDGVTYPGVVKEKAEAQKQYTAAVGRGESAGLVKTTGRKTEQFEVSVNVAPGSKTTFELIYQELLQRRLGMYELLLKVRPEQLVKHLQMDIYIFEPQGISTLETESTFMTQELANALTTSQNKTKAHIQFKPTLSQQRKSQNEQDTVLDGDFTVRYDVDRSSTGGTIQIENGYFVHHFAPEDLPTMAKNVLFVIDKSGSMAGKKIQQTREALIKILKDLSTQDQFNIIVFSGEANQWEQLLVQATEENLNRAVDYASKIPAQGGTNINKAVLSAVELLDKSNQAELLPSKSVSLIILLTDGEPTVGETNPKIIQKNTQEAINGRYSLFCLGFGFDVNYPFLEKLALDNGGLARRIYEDSDSALQLQDFYQEVANPLLSSVTFEYPSNAVEDVTRYNFQHHFKGSEMVVAGKLRDQGPDVLLAKVSGQMHLQNITFQTEASIAQQEKEFQGPKYIFHNFMERLWALLTIQQQLEQRISASGAELEALEAQVLNLSLKYNFVTPLTHMVVTKPEDQEQFQVAEKPTEVDGGVWSILSAVQRHFKTPTTGSKLLTSRLRGNRFQTLSRLGDGLVGSRQYMPPPGLPGPPGLPGPPGPPGHPHFASSIDYGRQPSLGRVLDLPSLSSQDPAGPSLAMLPKVVEQEGTTPEESPNPDHPRAPTIILPLPGSGVDQLCVDILHSEKPMKLFVDINQGLEVVGKYEKNIGFSWIEVTILKPHLQVHATPERLVVTRGRKNSEYKWKKTLFSVLPGLKMTMDKTGLLQLSGPDKVTISLLSLDDPQRGLMLLLNDTHHFSNDITGELGQFYQDIIWDDTKQTVRVLGIDYPATRELKLSYQDGFPGTEISCWTVKI", "length": 933 }, "evidence": [ { "id": "HGNC:6169", "url": "https://alliancegenome.org/gene/HGNC:6169#orthology", "database": "AGR" }, { "id": "MGI:109536", "url": "https://alliancegenome.org/gene/MGI:109536#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z906", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z906", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906" }, { "id": "PS51468", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51468" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VIT", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 147, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z906", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z906" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 273, "end_pos": 451, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 619 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 40, "end_pos": 42 }, { "start_pos": 479, "end_pos": 481 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9P823-1", "uniprot_ac": "A0A8M9P823", "uniprot_id": "A0A8M9P823_DANRE", "mass": { "chemical_mass": 37835.0, "monoisotopic_mass": 37835.0 }, "refseq": { "ac": "XP_021322453", "name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322453" }, "gene_names": [ { "name": "ndufaf6", "type": "recommended", "evidence": [ { "id": "A0A8M9P823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P823" } ] }, { "name": "ndufaf6", "type": "synonym", "evidence": [ { "id": "XP_021322453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322453" } ] } ], "protein_names": [ { "name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "type": "recommended", "evidence": [ { "id": "A0A8M9P823", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P823/entry#names_and_taxonomy" } ] }, { "name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322453" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322453.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322453", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322453" } ] }, { "annotation": "Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the biogenesis of complex I subunit MT-ND1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P823", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P823#function" }, { "database": "UniProtKB", "id": "ARBA00056665", "url": "https://www.uniprot.org/uniprotkb/ARBA00056665#function" }, { "database": "UniProtKB", "id": "A0AB32T359", "url": "https://www.uniprot.org/uniprotkb/A0AB32T359#function" } ] } ], "disease": [ { "disease_id": "DOID:0080761", "recommended_name": { "id": "DOID:0080761", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080761", "name": "Fanconi renotubular syndrome 5", "description": "A Fanconi syndrome that is characterized by proximal renotubular dysfunction from birth, followed by progressive kidney disease and pulmonary fibrosis and that has_material_basis_in homozygous mutation in the NDUFAF6 gene on chromosome 8q22." }, "synonyms": [ { "id": "DOID:0080761", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080761", "name": "Acadian-variant Fanconi syndrome", "description": "" }, { "id": "MONDO:0030056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030056", "name": "Fanconi renotubular syndrome 5", "description": "" }, { "id": "MONDO:0030056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030056", "name": "FANCONI RENOTUBULAR SYNDROME 5", "description": "" }, { "id": "MONDO:0030056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030056", "name": "FRTS5", "description": "" }, { "id": "MONDO:0030056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030056", "name": "Fanconi Renotubular Syndrome, Acadian Variant", "description": "" }, { "id": "MONDO:0030056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030056", "name": "Fanconi renotubular syndrome 5", "description": "" }, { "id": "MIM:618913", "resource": "MIM", "url": "https://www.omim.org/entry/618913", "name": "Fanconi renotubular syndrome 5", "description": "Fanconi renotubular syndrome 5" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080761", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080761" } ] }, { "disease_id": "DOID:0112078", "recommended_name": { "id": "DOID:0112078", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112078", "name": "nuclear type mitochondrial complex I deficiency 17", "description": "A nuclear type mitochondrial complex I deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the NDUFAF6 gene on chromosome 8q22.1." }, "synonyms": [ { "id": "DOID:0112078", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112078", "name": "MC1DN17", "description": "" }, { "id": "MONDO:0032622", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032622", "name": "mitochondrial complex I deficiency, nuclear type 17", "description": "" }, { "id": "MONDO:0032622", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032622", "name": "MC1DN17", "description": "" }, { "id": "MIM:618239", "resource": "MIM", "url": "https://www.omim.org/entry/618239", "name": "Mitochondrial complex I deficiency, nuclear type 17", "description": "Mitochondrial complex I deficiency, nuclear type 17" } ], "unlinked_id_list": [], "evidence": [ { "id": "0112078", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112078" } ] }, { "disease_id": "DOID:8466", "recommended_name": { "id": "DOID:8466", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8466", "name": "retinal degeneration", "description": "A retinal disease that is characterized by deterioration of the retina caused by the progressive and eventual death of the cells of the retina." }, "synonyms": [ { "id": "DOID:8466", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8466", "name": "degeneration of retina", "description": "" } ], "unlinked_id_list": [ "DOID:2007", "DOID:0070438" ], "evidence": [ { "id": "8466", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8466" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P823", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P823" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ndufaf6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P823", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100112-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100112-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P823", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P823", "database": "AlphaFoldDB", "categories": [] }, { "id": "569692", "url": "https://www.ncbi.nlm.nih.gov/gene/569692", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569692", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569692", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P823", "url": "https://www.orthodb.org/?gene=A0A8M9P823", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21181:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21181:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00494", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00494", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322453", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322453", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P823", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P823", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P823-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P823-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T359", "url": "https://www.uniprot.org/uniprotkb/A0AB32T359", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T359-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T359-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100112-1", "url": "https://zfin.org/ZDB-GENE-100112-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSCAMASSISIKNGLFTTKKSLHVNIPNPRCLQRQTEIKCTRAVTNSTRQHNEQYCIDIVRKKDYEGFLCSLLLPEAARRSALALRAFNVELAQIKDSVSHKTIGLMRMQFWKSAVEDIYRDDPPAQPVSAELWRAVRKHTLTRRWMLRIVSEREKDMEDRAYRNLQDLEAYGENTQSSLLYLLLETLGVKNVHADHAASHIGKAQGILTCLRATPFNSSRRKVYLPMDICMLHGASQEDFIRGSRDQNIRDVVYDIASQAHVHLQHARSFAESVPHSAMPAFLQTVVLEDYLQRVRKVDFDVFHPSLQKRNPTLPLQLYLRSWRKIY", "length": 328, "header": "tr|A0A8M9P823-1|A0A8M9P823_DANRE Isoform 1 of NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 OS=Danio rerio OX=7955 GN=ndufaf6 PE=1 SV=3 CANONICAL=A0A8M9P823-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P823-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P823/entry#A0A8M9P823-1", "sequence": { "sequence": "MSCAMASSISIKNGLFTTKKSLHVNIPNPRCLQRQTEIKCTRAVTNSTRQHNEQYCIDIVRKKDYEGFLCSLLLPEAARRSALALRAFNVELAQIKDSVSHKTIGLMRMQFWKSAVEDIYRDDPPAQPVSAELWRAVRKHTLTRRWMLRIVSEREKDMEDRAYRNLQDLEAYGENTQSSLLYLLLETLGVKNVHADHAASHIGKAQGILTCLRATPFNSSRRKVYLPMDICMLHGASQEDFIRGSRDQNIRDVVYDIASQAHVHLQHARSFAESVPHSAMPAFLQTVVLEDYLQRVRKVDFDVFHPSLQKRNPTLPLQLYLRSWRKIY", "length": 328, "header": "tr|A0A8M9P823-1|A0A8M9P823_DANRE Isoform 1 of NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 OS=Danio rerio OX=7955 GN=ndufaf6 PE=1 SV=3 CANONICAL=A0A8M9P823-1" }, "locus": {} }, { "isoform_ac": "A0AB32T359-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P823/entry#A0AB32T359-1", "sequence": { "sequence": "MRMQFWKSAVEDIYRDDPPAQPVSAELWRAVRKHTLTRRWMLRIVSEREKDMEDRAYRNLQDLEAYGENTQSSLLYLLLETLGVKNVHADHAASHIGKAQGILTCLRATPFNSSRRKVYLPMDICMLHGASQEDFIRGSRDQNIRDVVYDIASQAHVHLQHARSFAESVPHSAMPAFLQTVVLEDYLQRVRKVDFDVFHPSLQKRNPTLPLQLYLRSWRKIY", "length": 222, "header": "tr|A0AB32T359-1|A0A8M9P823_DANRE Computationally mapped isoform of NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 OS=Danio rerio OX=7955 GN=ndufaf6 PE=1 SV=2 CANONICAL=A0A8M9P823-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:569692", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569692", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AIL4-1", "protein_name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "gene_name": "Ndufaf6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATSMLGSVRGPRPFGLANLFHRQPPRDAWERVRRLPGPSAVRRSVAAASGPGIPGSHLYCLELLRKRDYESYLCSLLFPAECQRSASALRAFNVELAQVKDSVSEKTIGLMRMQFWKKAVEDMYCDNPPHQPVAIELWKAVKKHNLTKRWLMRIIDEREKNLDDKAYRSMQELENYAENTQGSLLYLTLEVLGVKDLHADHAASHIGKAQGIVTCLRATPYHSSRRQVFLPMDVCVQHGVSQEDFLRRNQDKNVRDVVYDIASQAHLHLKHARSFHRSVPAEAFPAFLQTVSLEDYLKKIQRVDFDIFHPSLQQKNMLLPLSLYIQSWRKRY", "length": 333 }, "evidence": [ { "id": "RGD:1309085", "url": "https://alliancegenome.org/gene/RGD:1309085#orthology", "database": "AGR" }, { "id": "HGNC:28625", "url": "https://alliancegenome.org/gene/HGNC:28625#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100112-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100112-1#orthology", "database": "AGR" }, { "id": "MGI:1924197", "url": "https://alliancegenome.org/gene/MGI:1924197#orthology", "database": "AGR" }, { "id": "FB:FBgn0030352", "url": "https://alliancegenome.org/gene/FB:FBgn0030352#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZN43-1", "protein_name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "gene_name": "Ndufaf6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATSMLGSVPGPRPFGLAGLFRRRPPRDPWERVRRLPRLSAVRRSVAAASGPGIPDSHLYCLELLRKRDYESYLCSLLFPAECQRSASALRAFNVELAQVKDSVSEKTIGLMRMQFWRKAVEDMFCDNPPHQPVAMELWKAVKRHNLTKRWLLRIIDEREKNLDDKAYRSIRELETYAENTQSSLLYLTLEVLGVKDVHADHAASHIGKAQGIVTCLRATPYHSSRRQVFLPMDVCVQHGVSQEDFLRRNQDKNVRDVVYDIASQAHLHLKHARSFHSRVPAEAFPAFLQTVSLEDYLKKIQRVDFDIFHPSLQQKNTLLPLSLYIQSWRKRY", "length": 333 }, "evidence": [ { "id": "RGD:1309085", "url": "https://alliancegenome.org/gene/RGD:1309085#orthology", "database": "AGR" }, { "id": "HGNC:28625", "url": "https://alliancegenome.org/gene/HGNC:28625#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100112-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100112-1#orthology", "database": "AGR" }, { "id": "MGI:1924197", "url": "https://alliancegenome.org/gene/MGI:1924197#orthology", "database": "AGR" }, { "id": "FB:FBgn0030352", "url": "https://alliancegenome.org/gene/FB:FBgn0030352#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q330K2-1", "protein_name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6", "gene_name": "NDUFAF6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASAHGSVWGPLRLGIPGLCCRRPPLGLYARMRRLPGPEVSGRSVAAASGPGAWGTDHYCLELLRKRDYEGYLCSLLLPAESRSSVFALRAFNVELAQVKDSVSEKTIGLMRMQFWKKTVEDIYCDNPPHQPVAIELWKAVKRHNLTKRWLMKIVDEREKNLDDKAYRNIKELENYAENTQSSLLYLTLEILGIKDLHADHAASHIGKAQGIVTCLRATPYHGSRRKVFLPMDICMLHGVSQEDFLRRNQDKNVRDVIYDIASQAHLHLKHARSFHKTVPVKAFPAFLQTVSLEDFLKKIQRVDFDIFHPSLQQKNTLLPLYLYIQSWRKTY", "length": 333 }, "evidence": [ { "id": "RGD:1309085", "url": "https://alliancegenome.org/gene/RGD:1309085#orthology", "database": "AGR" }, { "id": "HGNC:28625", "url": "https://alliancegenome.org/gene/HGNC:28625#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100112-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100112-1#orthology", "database": "AGR" }, { "id": "MGI:1924197", "url": "https://alliancegenome.org/gene/MGI:1924197#orthology", "database": "AGR" }, { "id": "FB:FBgn0030352", "url": "https://alliancegenome.org/gene/FB:FBgn0030352#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VYS5-1", "protein_name": "NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 homolog", "gene_name": "sicily", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRRLVRNWNCRLLFNAKSGQEIVSHAGIHQEAKTNAIPREKKVIEADKNGYGAKHCMSLVEKYDYENYLCTLLLPRELRRAAFALRAFNVEVSRSVSGHQIEPQIAKMRLKFWHDSIDKCFEPDSQRSYVEDQPVLRELKHTVGSRKLNKVYLRRLVTARERPPTHAFESIRELEEYTEQTFSSLLLLLLEVGGVRDLNADHAASHLGKAQGIATLLRSIPLAGRQQAPCIPLEVLVLHGVSQERIIRSKSDDKGVEDCIFDVASAANTHLKLARQLHDKVPPQVRKIFLSAVATDAYLERLRRANFLLTHKSCVGRDTLLPARLFWKSLLNRF", "length": 334 }, "evidence": [ { "id": "RGD:1309085", "url": "https://alliancegenome.org/gene/RGD:1309085#orthology", "database": "AGR" }, { "id": "HGNC:28625", "url": "https://alliancegenome.org/gene/HGNC:28625#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100112-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100112-1#orthology", "database": "AGR" }, { "id": "MGI:1924197", "url": "https://alliancegenome.org/gene/MGI:1924197#orthology", "database": "AGR" }, { "id": "FB:FBgn0030352", "url": "https://alliancegenome.org/gene/FB:FBgn0030352#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P823", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P823" } ], "pmid": "" }, { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P823", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P823" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P823", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P823" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 }, { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z9M8-1", "uniprot_ac": "A0A8M6Z9M8", "uniprot_id": "A0A8M6Z9M8_DANRE", "mass": { "chemical_mass": 75981.0, "monoisotopic_mass": 75981.0 }, "refseq": { "ac": "XP_017214324", "name": "synaptotagmin-14 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214324" }, "gene_names": [ { "name": "syt14a", "type": "recommended", "evidence": [ { "id": "A0A8M6Z9M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8" } ] }, { "name": "syt14a", "type": "synonym", "evidence": [ { "id": "XP_017214324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214324" } ] } ], "protein_names": [ { "name": "Synaptotagmin-14 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z9M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8/entry#names_and_taxonomy" } ] }, { "name": "synaptotagmin-14 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017214324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214324" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214324" } ] } ], "disease": [ { "disease_id": "DOID:0080063", "recommended_name": { "id": "DOID:0080063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080063", "name": "autosomal recessive spinocerebellar ataxia 11", "description": "An autosomal recessive cerebellar ataxia that has_material_basis_in homozygous mutation in the SYT14 gene on chromosome 1q32." }, "synonyms": [ { "id": "DOID:0080063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080063", "name": "SCAR11", "description": "" }, { "id": "MONDO:0013645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013645", "name": "autosomal recessive spinocerebellar ataxia 11", "description": "Any autosomal recessive syndromic cerebellar ataxia in which the cause of the disease is a mutation in the SYT14 gene." }, { "id": "MONDO:0013645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013645", "name": "SCAR11", "description": "" }, { "id": "MONDO:0013645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013645", "name": "SYT14 autosomal recessive syndromic cerebellar ataxia", "description": "" }, { "id": "MONDO:0013645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013645", "name": "autosomal recessive spinocerebellar ataxia 11", "description": "" }, { "id": "MONDO:0013645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013645", "name": "autosomal recessive spinocerebellar ataxia type 11", "description": "" }, { "id": "MONDO:0013645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013645", "name": "autosomal recessive syndromic cerebellar ataxia caused by mutation in SYT14", "description": "" }, { "id": "MONDO:0013645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013645", "name": "spinocerebellar ataxia, autosomal recessive type 11", "description": "" }, { "id": "MONDO:0013645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013645", "name": "spinocerebellar ataxia, autosomal recessive 11", "description": "" }, { "id": "MIM:614229", "resource": "MIM", "url": "https://www.omim.org/entry/614229", "name": "Spinocerebellar ataxia, autosomal recessive, 11", "description": "Spinocerebellar ataxia, autosomal recessive, 11" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080063" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "syt14a", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-200", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-200", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z9M8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z9M8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08389", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08389", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd08408", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08408", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "564702", "url": "https://www.ncbi.nlm.nih.gov/gene/564702", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564702", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564702", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1S5", "url": "https://www.orthodb.org/?gene=A0A8M6Z1S5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z9M8", "url": "https://www.orthodb.org/?gene=A0A8M6Z9M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46129", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46129", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46129:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46129:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017214324", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214324", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1S5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z9M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PYR8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PYR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PYR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PYR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T553", "url": "https://www.uniprot.org/uniprotkb/A0AB32T553", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T553-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T553-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2N9", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2N9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2N9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2N9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2Q5", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-200", "url": "https://zfin.org/ZDB-GENE-090313-200", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAFFKSFQQSLPSVSAMLESVTEKVDDLAFALSDVTYTVTGELAEHVNTIIHKVQAEELKRIRKKEAEEKEAAARQVQERRDTFLDRAKIQTQAASGLVEDPEPQIAKNDNCSVLSIETLSSESDLSQTPDMLIEKFKAQNSADALSVCQQNGSCIKETSESTKAKPSSPADGNEKKKSSSRDAEEKSYVNADYHCSSSDSDDEVIGQYQEAVSRSQGLRGGAARTNSRHQKGYGWDTRQKYSPLAAEYDGYSSEASADDVNCIQRMRRTPPLDELQPPPYQDEDGSPRMSCTPSDLGDAKCDLSHGSDSPRHSYGKCPSELSGAQETESFLNKGYEEDVPSDSTAVLSPEDLSARGSAAQLPKGYDPEPLAQYGTLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIILDPYCNIPGSDSQASMSDVSCSETASSYPSAAQGSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTEMKESKGQQVCRWHSLLES", "length": 687, "header": "tr|A0A8M6Z9M8-1|A0A8M6Z9M8_DANRE Isoform 1 of Synaptotagmin-14 isoform X1 OS=Danio rerio OX=7955 GN=syt14a PE=3 SV=1 CANONICAL=A0A8M6Z9M8-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8/entry#A0A8M6Z1S5-1", "sequence": { "sequence": "MAFFKSFQQSLPSVSAMLESVTEKVDDLAFALSDVTYTVTGELAEHVNTIIHKVQAEELKRIRKKEAEEKEAAARQVQERRDTFLDRAKIQTQAASGLVEDPEPQIAKNDNCSVLSIETLSSESDLSQTPDMLIEKFKAQNSADALSVCQQNGSCIKETSESTKAKPSSPADGNEKKKSSSRDAEEKSYVNADYHCSSSDSDDEVIGQYQEAVSRSQGLRGGAARTNSRHQKGYGWDTRQKYSPLAAEYDGYSSEASADDVNCIQRMRRTPPLDELQPPPYQDEDGSPRMSCTPSDLGDAKCDLSHGSDSPRHSYGKCPSELSGAQETESFLNKGYEEDVPSDSTAVLSPEDLSARGSAAQLPKGYDPEPLAQYGTLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIILDPYCNIPGSDSQASMSDVSCSETASSYPSAAQGSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTEMKESKGQQVCRWHSLLES", "length": 668, "header": "tr|A0A8M6Z1S5-1|A0A8M6Z9M8_DANRE Computationally mapped isoform of Synaptotagmin-14 isoform X1 OS=Danio rerio OX=7955 GN=syt14a PE=3 SV=1 CANONICAL=A0A8M6Z9M8-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z9M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8/entry#A0A8M6Z9M8-1", "sequence": { "sequence": "MAFFKSFQQSLPSVSAMLESVTEKVDDLAFALSDVTYTVTGELAEHVNTIIHKVQAEELKRIRKKEAEEKEAAARQVQERRDTFLDRAKIQTQAASGLVEDPEPQIAKNDNCSVLSIETLSSESDLSQTPDMLIEKFKAQNSADALSVCQQNGSCIKETSESTKAKPSSPADGNEKKKSSSRDAEEKSYVNADYHCSSSDSDDEVIGQYQEAVSRSQGLRGGAARTNSRHQKGYGWDTRQKYSPLAAEYDGYSSEASADDVNCIQRMRRTPPLDELQPPPYQDEDGSPRMSCTPSDLGDAKCDLSHGSDSPRHSYGKCPSELSGAQETESFLNKGYEEDVPSDSTAVLSPEDLSARGSAAQLPKGYDPEPLAQYGTLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIILDPYCNIPGSDSQASMSDVSCSETASSYPSAAQGSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTEMKESKGQQVCRWHSLLES", "length": 687, "header": "tr|A0A8M6Z9M8-1|A0A8M6Z9M8_DANRE Isoform 1 of Synaptotagmin-14 isoform X1 OS=Danio rerio OX=7955 GN=syt14a PE=3 SV=1 CANONICAL=A0A8M6Z9M8-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PYR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8/entry#A0A8M9PYR8-1", "sequence": { "sequence": "MAIDGGERNCGVHELICIRKVSPEALGFLSGIGVFIFLVIVLFLYLNNKLSLESANQLPSLDQYRKSAEPAEKSYVNADYHCSSSDSDDEVIGQYQEAVSRSQGLRGGAARTNSRHQKGYGWDTRQKYSPLAAEYDGYSSEASADDVNCIQRMRRTPPLDELQPPPYQDEDGSPRMSCTPSDLGDAKCDLSHGSDSPRHSYGKCPSELSGAQETESFLNKGYEEDVPSDSTAVLSPEDLSARGSAAQLPKGYDPEPLAQYGTLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIILDPYCNIPGSDSQASMSDVSCSETASSYPSAAQGSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTEMKESKGQQVCRWHSLLES", "length": 573, "header": "tr|A0A8M9PYR8-1|A0A8M6Z9M8_DANRE Computationally mapped isoform of Synaptotagmin-14 isoform X1 OS=Danio rerio OX=7955 GN=syt14a PE=3 SV=2 CANONICAL=A0A8M6Z9M8-1" }, "locus": {} }, { "isoform_ac": "A0AB32T553-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8/entry#A0AB32T553-1", "sequence": { "sequence": "MAIDVSPEALGFLSGIGVFIFLVIVLFLYLNNKLSLESANQLPSLDQYRKSAEPAEKSYVNADYHCSSSDSDDEVIGQYQEAVSRSQGLRGGAARTNSRHQKGYGWDTRQKYSPLAAEYDGYSSEASADDVNCIQRMRRTPPLDELQPPPYQDEDGSPRMSCTPSDLGDAKCDLSHGSDSPRHSYGKCPSELSGAQETESFLNKGYEEDVPSDSTAVLSPEDLSARGSAAQLPKGYDPEPLAQYGTLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIILDPYCNIPGSDSQASMSDVSCSETASSYPSAAQGSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTEMKESKGQQVCRWHSLLES", "length": 557, "header": "tr|A0AB32T553-1|A0A8M6Z9M8_DANRE Computationally mapped isoform of Synaptotagmin-14 isoform X1 OS=Danio rerio OX=7955 GN=syt14a PE=3 SV=1 CANONICAL=A0A8M6Z9M8-1" }, "locus": {} }, { "isoform_ac": "A0AC58H2N9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8/entry#A0AC58H2N9-1", "sequence": { "sequence": "MAIDVSPEALGFLSGIGVFIFLVIVLFLYLNNKLSLESANQLPSLDQYRKSAEPAEKSYVNADYHCSSSDSDDEVIGQYQEAVSRSQGLRGGAARTNSRHQKGYGWDTRQKYSPLAAEYDGYSSEASADDVNCIQRMRRTPPLDELQPPPYQDEDGSPRMSCTPSDLGDAKCDLSHGSDSPRHSYGKCPSELSGAQETESFLNKGYEEDVPSDSTAVLSPEDLSARGSAAQLPKGYDPEPLAQYGTLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIILDPYCNIPGSDSQASMSDVSCSETASSYPSAAQGSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTEMKESKGQQVCRWHSLLES", "length": 538, "header": "tr|A0AC58H2N9-1|A0AC58H2N9_DANRE Computationally mapped isoform of Synaptotagmin-14 isoform X6 OS=Danio rerio OX=7955 GN=syt14a PE=3 SV=1 CANONICAL=A0A8M6Z9M8-1" }, "locus": {} }, { "isoform_ac": "A0AC58H2Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8/entry#A0AC58H2Q5-1", "sequence": { "sequence": "MAIDGGERNCGVHELICIRKVSPEALGFLSGIGVFIFLVIVLFLYLNNKLSLESANQLPSLDQYRKSAEPAEKSYVNADYHCSSSDSDDEVIGQYQEAVSRSQGLRGGAARTNSRHQKGYGWDTRQKYSPLAAEYDGYSSEASADDVNCIQRMRRTPPLDELQPPPYQDEDGSPRMSCTPSDLGDAKCDLSHGSDSPRHSYGKCPSELSGAQETESFLNKGYEEDVPSDSTAVLSPEDLSARGSAAQLPKGYDPEPLAQYGTLDVVFDYDSSDQRLSISITALTDIPSLKRTGNISWQVHLVLLPTKKQRAKTIIQRGPCPVFTETFHFSHIESEMIGNYAIRFRLYSVRRMKKEKALGEKVFYLTKLNLQGKMSVPIILDPYCNIPGSDSQASMSDVSCSETASSYPSAAQGSAPEILLGLVYNATTGRLSVEVIKGSHFKNLAANKPPNTYVKLTLLNSMGQEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELTHWTEMKESKGQQVCRWHSLLES", "length": 554, "header": "tr|A0AC58H2Q5-1|A0AC58H2Q5_DANRE Computationally mapped isoform of Synaptotagmin-14 isoform X5 OS=Danio rerio OX=7955 GN=syt14a PE=3 SV=1 CANONICAL=A0A8M6Z9M8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:564702", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564702", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KF61-1", "protein_name": "Synaptotagmin 14, isoform D", "gene_name": "Syt14", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIVTSASGLDSTPTLGTIEVTTLLGAFFGVLVLLLLLFLFISRKCCFHYRHAINCCDERHLAVKCVQKITRKRRYENTSSDSEEDILRRLRWHQQHQLGEKPGGYGLGISQANPLTAQSFNYHQAGASADLQRVTVSRDPLAIAERGKVGIPSSHSECSSNDSMEVSVDSHTGVLTGLSKATTTVPHPATAFRNPCGEHRAKTQALRYQHRVNVAAPPKLDKERDNVLVVPMVNAYSINNNNNSITTSNNHPSSNNNDDEPLFDTSDLRSIKSDDLLVGVDQKEPAVQRGPIELELSLLYDAPMRKMTVHVMQAKNLPPLGSGQTTHTQVRMLMLPSKKQKLKTKIRSGENPQYMESFLLHRVNPEDVNNMGLRVRLYGCERLRKERLIGEAYVSFATVDLELETNLWLPLEPRNTSSGLGSTSDLLSLARSESAGSTSSMQHGGVSELLLGLSYNGVTGRLSVEIIKGSQFRSLSLNKAPDTYVKMVMVSSIGQEISRAKTSIRRGQPNPLFKETFAFQVALFQLNDVTLMISVYAKRHMKKNEMVGWFSLGLNSSGSEEVAHWADVCEMPKGEMLARWHVLVDSXFEQLGQSSGRSGKALRKLSLAAFKDRSREKSSKESRLEENGAQFHAAVALDIEPGLELDFV", "length": 648 }, "evidence": [ { "id": "HGNC:23143", "url": "https://alliancegenome.org/gene/HGNC:23143#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-200", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-200#orthology", "database": "AGR" }, { "id": "MGI:2444490", "url": "https://alliancegenome.org/gene/MGI:2444490#orthology", "database": "AGR" }, { "id": "RGD:1592654", "url": "https://alliancegenome.org/gene/RGD:1592654#orthology", "database": "AGR" }, { "id": "FB:FBgn0261086", "url": "https://alliancegenome.org/gene/FB:FBgn0261086#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A0G2K644-1", "protein_name": "Synaptotagmin 16", "gene_name": "Syt16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLVMASQDVQNFFQPLSSWLSRVYEALQQAGDALSASLVLLSKHDSALSDKPEQDLDAIQIQETCLEDGEQDNDGGPEETGSLFLEEDHFSSSNSDLRDSVQTASLRLGQQAKDSSTVISQWPNKIPGGPKPPHVLSSIAEEEHHSEGQRCDLQHGSDTQLPGSLEKVNGRKQANSFGDDEEPSTSSESDEDVTKQFEISVSRSQSFRTGVPEKGKTTELEQKTKCKHFLCTHQEDSAEGSACEDLDGPSQLSYSEIRSYEDRPISILSQSPCESRDTRHHGPCHLGAGVVRNLSRPCADGILETETAFISRGFEDPYATHNSSMWSPEEQDGTSLQVPPRLPEPISKCGDLDVIFEYRAVTQKLTVTIVRAQGLPDKDRSGVNSWQVHIVLLPSKKQRGKTNIQRGPNPVFKEKVTFTKLEPRDVAACAVRFRLYAARKMTRERMMGEKLFCLSHLHPEGEMKVTLVLEPRSNLSSGESPLSPSVVSHSDSASSTQSLSHGGVPELLVGLSYNATTGRLSVEMIKGSHFRNLAANRAPDTYGKLFLLNCVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISIYSRRTMKRKEMIGWIALGQNSSGEEEQEHWDEMKDSKSQQICRWHTLLES", "length": 644 }, "evidence": [ { "id": "FB:FBgn0261086", "url": "https://alliancegenome.org/gene/FB:FBgn0261086#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMJ4-1", "protein_name": "Synaptotagmin 14", "gene_name": "Syt14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFFKSFQQNLPSVSSLVDTISSAVEDLSTAVGEVSYAITDSVAGQVANMMHGFCPEEGSCTAEEATGSSKAQSTALQDTSTSKNTAHQKAQSDLDQKAKQTTGCNTSTPQRQEQEIYKQGLHIHEGQWATSEYQETGEAGGAAVKGLMSDGISAVKQKMRPAPTCHELEQTDKCEVSGVGNSGSDTNGLNKVSYQDVKGSLSSSGQNFLSVQKCMVTDSSKARLQHVPVGREQEKSGTVTKSKRLSDLEHSEHLEKAKSRNKHNGFKGNERSGNDHSPDDSTRNSRYRAQRSNAKEDTHSAPSTHCKNVFPRRIKEKTNPTKCDKVKGDMKAKKNEASSAKRGTAKSKVGKYSKILPEKDNSYMDRDEPGSSSESEDEALGKYHEALSRTHNSRWPLVDSRQKSYTWETRQKYSPLSAEYDGYSTEASIEDGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDAKCEISHCSNSPRCSFNKCPSEGSTGHEAESYHNKGYEDDVPSDSTAVLSPEDMSAQGSASQLPKPFDPEPEAKYGTLDVTFDYDSERQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNPSGCDSQVSLSEVSCGDSTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNGLFCCLKHLIGGQVYIIRDTYVKLTLLNSMGQEMSKCKTSTRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELRHWSAMKESKGQQVCRWHALLES", "length": 859 }, "evidence": [ { "id": "HGNC:23143", "url": "https://alliancegenome.org/gene/HGNC:23143#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-200", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-200#orthology", "database": "AGR" }, { "id": "MGI:2444490", "url": "https://alliancegenome.org/gene/MGI:2444490#orthology", "database": "AGR" }, { "id": "RGD:1592654", "url": "https://alliancegenome.org/gene/RGD:1592654#orthology", "database": "AGR" }, { "id": "FB:FBgn0261086", "url": "https://alliancegenome.org/gene/FB:FBgn0261086#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AB32TC14-1", "protein_name": "Synaptotagmin-14b isoform X1", "gene_name": "syt14b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFFKSFQQNLPSVSSLLDSVSNTVSTAVDDLSTAVSDVTYTVSDQLTEQVNTIINKVQTEEDGKSGKDAEGSSDDVQKDRKLKRQDTEADADGESRRSRKSKKNSMWTIEVDEAEIQREKERQEEARRAEEEEWEWCYAPSKGWYRKRKDPNQPSQTSDNQTSNTEQESKEVGTLEESTSLSGKHKKEGDHHKENANGVHTSNSQEEQDSQEMSGDPDTSTSNIDRNGENCSEKIEEDEDEVSHEEGKTQKKKGKVFSDEEQEEAVQDSKNSKAKSKAKKNKECKDGGCAEKGSESEDETQKKHKDSHQQRSGWRNRDEENEDCSSEASAELVKRKKGSSSLNELQPPPYRDKDDVKRGSRGRSDSAEGSGSEISEGTEDPEDTESYLNKGYEEDAPSDSTAVLGPEDSLIPPLPESYEPEALGKYGTLDVAFEYDPGEQRLAVTVTAATDIPTLKSTGNISWQVHLVLLPTKKQRAKTGVQKGPCPVFTETFRFSCVEEDALGDYAVRFRLYSVRRMKKEKVLGEKVFYLTKLNLQGKLALPVTLEPGTSVPGCGSVVSVSRSAGALSCRSTGESSIPELLLGLLYNSTTGRLSAEVIKGSHFKNSASDKLPIGLFCCVKHFISGQLYIMRDTYVKLTMLDSKGKEMSKCKTSVCRGQPNPTYKETFVFQVALFQLSEVTLQVSVYSRRSSMKRRERVGWVALGLNSTTEEQEEHWTQMKESEGQQVCHWHTLIDS", "length": 738 }, "evidence": [ { "id": "HGNC:23143", "url": "https://alliancegenome.org/gene/HGNC:23143#orthology", "database": "AGR" }, { "id": "MGI:2444490", "url": "https://alliancegenome.org/gene/MGI:2444490#orthology", "database": "AGR" }, { "id": "RGD:1592654", "url": "https://alliancegenome.org/gene/RGD:1592654#orthology", "database": "AGR" }, { "id": "FB:FBgn0261086", "url": "https://alliancegenome.org/gene/FB:FBgn0261086#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q17RD7-1", "protein_name": "Synaptotagmin-16", "gene_name": "SYT16", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLAMASQDVQNFFQPFSSWISRVYEALQQAGDMLSASLVNISKQDSKLSDKLDQDLDNIQIQETYFEDEEQDNDWSQEDANSLFLEVDHFSCCNSDLQDSAQNSSPSLSQHAKDSCSTMSQWPNWASDDRKLPHVLSSIAEEEHHLEKQRSGLQHGFDSQLPGTLETVNGKKQVNSFGDDEELSTSSDSDEEVIKQFEISVSRSQSFRSVTSEKGKQTGLEQKPKFSRSLLTHGEDGTEVSACEDLDGASQRRYSENLSYGEDDHIPAHSQSPCERGDAKHHGTSHQESSVVQSLRRQSTEGSLEMETAFNSRGFEDSYATDSSSMWSPEEQDRTNLQVPSGVSEPISKCGDLDVIFEYRAASQKLTVTIVRAQGLPDKDRSGVNSWQVHVVLLPGKKHRGRTNIQRGPNPVFREKVTFAKLEPRDVAACAVRFRLYAARKMTRERMMGEKLFYLSHLHPEGEMKVTLVLEPRSNISSGGSPLSPSAVSHSDSTSSTQSLSHGGAPELLVGLSYNATTGRLSVEMIKGSHFRNLAVNRAPDTYGKLFLLNSVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISVYNRRTMKRKEMIGWIALGQNSSGEEEQDHWEEMKETKGQQICRWHTLLES", "length": 645 }, "evidence": [ { "id": "FB:FBgn0261086", "url": "https://alliancegenome.org/gene/FB:FBgn0261086#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q58G82-1", "protein_name": "Putative synaptotagmin-14-like protein", "gene_name": "SYT14P1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLEGFQILVQNTVQGTIHKIKCVCDSQMSVSEMSCSESTSACQSLEDGSVPEILISLLYNATNGRLSAEVIKGSHLKNWAANRPPNTYVKLTLRKSTDQEMSKCKISIRRGRPNPVYKETFVFKVTLFQLSHVTLMLSVYNKSSMRRKMIGWIYLGLNSSGEELNHWTEMKESKGRQVRRWQALLESR", "length": 188 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-200", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-200#orthology", "database": "AGR" }, { "id": "HGNC:33429", "url": "https://alliancegenome.org/gene/HGNC:33429#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TN83-1", "protein_name": "Synaptotagmin-16", "gene_name": "Syt16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLTMASQDVQNFFQPLSSWLSRVYEALQQAGDALSASLVLLSKHDSALSDKPEQDLDAAQIQQTYLEDEEQDHDGSPEEASSLFLEEDHFSLSNSDLQDSVQTASPTLGQQAEDSSSVIPPWPSKIPGAPKPQPVLSSIAEEDHHSERQRCGRQHGSGTLEKVNGRKQVNSFGDDEEPSTSSESDEDVTKQFKISVSRSQSFRSGVSEKGKTTELEQKIKCKRLLCTHQEDSAEGSACEDLDRTSQLSYSEILSYEDRPISILPQSPFESRNVRHHGPCRPEMGMVRSLGRPCADGVLETETAFVSRGFEDSYATHSSSLWSPEEQDGTSLQVPHRLLEPISKCGDLDVIFEYRAVTQKLTVTIVRAQGLPDKDRSGVNSWQVHIVLLPSKKQRGKTNIQRGPNPVFKEKVTFTKLEPRDVASCAVRFRLYAARKMTRERMMGEKLFCLSHLHPEGEMKVTLVLEPRSNLSSGESPLSPSVVSHSDSASSTQSLSHGGVPELLVGLSYNATTGRLSVEMIKGSHFRNLAANRAPDTYGKLFLLNCVGQEMSRCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLMISIYSRRTMKRKEMIGWVALGQNSSGEEEQEHWEEMKESKGQQTCRWHTLLES", "length": 639 }, "evidence": [ { "id": "FB:FBgn0261086", "url": "https://alliancegenome.org/gene/FB:FBgn0261086#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TN84-1", "protein_name": "Synaptotagmin-14", "gene_name": "Syt14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIEGGERTCGVHELICIRKVSPEAVGFLSAVGVFIVLMLLLFLYINKKFCFENVGGFPDLGSGYNTRTNSQDKMYNSYMDRDEPGSSSESEDEALGKYHEALSRTHNSRWPLVDSRQKSYAWETRQKYSPLSAEYDGYSTEASMEDGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDAKCEISHCSNSPRCSFNKCPSEGSTGHEAESYHNKGYEDDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSERQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNPSGCDSQVSLSEASCGDSTSSCQSLQHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSTRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNRRSMKRKEMIGWISLGLNSSGEEELRHWTAMKESKGQQVCRWHALLES", "length": 555 }, "evidence": [ { "id": "HGNC:23143", "url": "https://alliancegenome.org/gene/HGNC:23143#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-200", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-200#orthology", "database": "AGR" }, { "id": "MGI:2444490", "url": "https://alliancegenome.org/gene/MGI:2444490#orthology", "database": "AGR" }, { "id": "RGD:1592654", "url": "https://alliancegenome.org/gene/RGD:1592654#orthology", "database": "AGR" }, { "id": "FB:FBgn0261086", "url": "https://alliancegenome.org/gene/FB:FBgn0261086#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NB59-1", "protein_name": "Synaptotagmin-14", "gene_name": "SYT14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAIEGGERTCGVHELICIRKVSPEAVGFLSAVGVFIILMLLLFLYINKKFCFENVGGFPDLGSEYSTRKNSQDKIYNSYMDKDEHGSSSESEDEALGKYHEALSRTHNSRLPLADSRQRNYAWETRQKYSPLSAEYDGYSSEASIDEGNCIQRMRRTPPLDELQPPPYQDDSGSPHLSCTPSEIGDSKCEFSHCSNSPRCSYNKCPSEGSTGHEIESFHNKGYEEDVPSDSTAVLSPEDMSAQGSSSQLPKPFDPEPEAKYGTLDVTFDYDSQEQKLLVTVTAVTDIPTYNRTGGNSWQVHLVLLPIKKQRAKTSIQRGPCPVFTETFKFNHVESEMIGNYAVRFRLYGVHRMKKEKIVGEKIFYLTKLNLQGKMSLPVILEPSYNHSGCDSQMSVSEMSCSESTSSCQSLEHGSVPEILIGLLYNATTGRLSAEVIKGSHFKNLAANRPPNTYVKLTLLNSMGQEMSKCKTSIRRGQPNPVYKETFVFQVALFQLSDVTLILSVYNKRSMKRKEMIGWISLGLNSSGEEELNHWTEMKESKGQQVCRWHALLES", "length": 555 }, "evidence": [ { "id": "HGNC:23143", "url": "https://alliancegenome.org/gene/HGNC:23143#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-200", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-200#orthology", "database": "AGR" }, { "id": "MGI:2444490", "url": "https://alliancegenome.org/gene/MGI:2444490#orthology", "database": "AGR" }, { "id": "RGD:1592654", "url": "https://alliancegenome.org/gene/RGD:1592654#orthology", "database": "AGR" }, { "id": "FB:FBgn0261086", "url": "https://alliancegenome.org/gene/FB:FBgn0261086#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 539, "end_pos": 541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 657, "end_pos": 659, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z9M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9M8" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 373, "end_pos": 492, "start_aa": "Gln", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 152, "end_pos": 154 }, { "start_pos": 408, "end_pos": 410 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 657, "end_pos": 659 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9NZW7-1", "uniprot_ac": "A0A8M9NZW7", "uniprot_id": "A0A8M9NZW7_DANRE", "mass": { "chemical_mass": 64935.0, "monoisotopic_mass": 64935.0 }, "refseq": { "ac": "XP_021322707", "name": "raftlin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322707" }, "gene_names": [ { "name": "rftn1b", "type": "recommended", "evidence": [ { "id": "A0A8M9NZW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW7" } ] }, { "name": "rftn1b", "type": "synonym", "evidence": [ { "id": "XP_021322707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322707" } ] } ], "protein_names": [ { "name": "Raftlin isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9NZW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW7/entry#names_and_taxonomy" } ] }, { "name": "raftlin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322707" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021322707.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322707" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZW7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rftn1b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120426-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120426-5", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9NZW7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9NZW7", "database": "AlphaFoldDB", "categories": [] }, { "id": "101885083", "url": "https://www.ncbi.nlm.nih.gov/gene/101885083", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028169", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028169", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885083", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885083", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9NZW7", "url": "https://www.orthodb.org/?gene=A0A8M9NZW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17601", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17601", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17601:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17601:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322707", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9NZW7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9NZW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T607", "url": "https://www.uniprot.org/uniprotkb/A0AB32T607", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T607-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T607-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T8W4", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T8W4-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLM1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120426-5", "url": "https://zfin.org/ZDB-GENE-120426-5", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGCGLRKLRQTEDNSPGKIYSTLKRPQVETKTGVSYTYSHLDFVVGKDADGTSSLCLSSVRDLPSQLQDLYQQGFILTAVHPFIHPSGPESSSVQRQIYRALLIRVSDGWEKNPADFEPYHLKLEECMSAEQIPSTEHIQGYVKKQIQDAADQGIIFVGFIQEPAGLRPHALQLGEPEEASLSLHSSPSSLHGSGLTPCPSPLEEPEPEPNPELGDESGAENQEQKQGGEALKAGGDAGGDENSETLTHNNNDTDKSTDTSQKTSRLALNKSGAELFGLFNYPGRRSAQLKYYTVKVPLRVQTQSDGIWSLEANWLDHMTQHFNNGASLVDGYFQINNHNNDVLVKTVDSVFVFQEGVEGDTNSAAAYDAIVVEQWTIIDGLEVKTDYIPLLQSLASFGWRLTCVLPTPITKTNSDGSLATKQIVFLQRPVLPRKKKESKKVIFKARNKSNKNSVKDAPKNKKKKDSTPTVEKEISDQKAERSVEDTNTSVNERRPEKQNNEADAQVQSQQKQDTEEGKWAEEVTAAGSEVGGEKQDEVSGNSEKDEGAKDEVDGKAEEQSVKIEAETGSCKDQKGDDEGDKPDEPSANQD", "length": 591, "header": "tr|A0A8M9NZW7-1|A0A8M9NZW7_DANRE Isoform 1 of Raftlin isoform X1 OS=Danio rerio OX=7955 GN=rftn1b PE=3 SV=2 CANONICAL=A0A8M9NZW7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9NZW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW7/entry#A0A8M9NZW7-1", "sequence": { "sequence": "MGCGLRKLRQTEDNSPGKIYSTLKRPQVETKTGVSYTYSHLDFVVGKDADGTSSLCLSSVRDLPSQLQDLYQQGFILTAVHPFIHPSGPESSSVQRQIYRALLIRVSDGWEKNPADFEPYHLKLEECMSAEQIPSTEHIQGYVKKQIQDAADQGIIFVGFIQEPAGLRPHALQLGEPEEASLSLHSSPSSLHGSGLTPCPSPLEEPEPEPNPELGDESGAENQEQKQGGEALKAGGDAGGDENSETLTHNNNDTDKSTDTSQKTSRLALNKSGAELFGLFNYPGRRSAQLKYYTVKVPLRVQTQSDGIWSLEANWLDHMTQHFNNGASLVDGYFQINNHNNDVLVKTVDSVFVFQEGVEGDTNSAAAYDAIVVEQWTIIDGLEVKTDYIPLLQSLASFGWRLTCVLPTPITKTNSDGSLATKQIVFLQRPVLPRKKKESKKVIFKARNKSNKNSVKDAPKNKKKKDSTPTVEKEISDQKAERSVEDTNTSVNERRPEKQNNEADAQVQSQQKQDTEEGKWAEEVTAAGSEVGGEKQDEVSGNSEKDEGAKDEVDGKAEEQSVKIEAETGSCKDQKGDDEGDKPDEPSANQD", "length": 591, "header": "tr|A0A8M9NZW7-1|A0A8M9NZW7_DANRE Isoform 1 of Raftlin isoform X1 OS=Danio rerio OX=7955 GN=rftn1b PE=3 SV=2 CANONICAL=A0A8M9NZW7-1" }, "locus": {} }, { "isoform_ac": "A0AB32T607-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW7/entry#A0AB32T607-1", "sequence": { "sequence": "MGCGLRKLRQTEDNSPGKIYSTLKRPQVETKTGVSYTYSHLDFVVGKDDGTSSLCLSSVRDLPSQLQDLYQQGFILTAVHPFIHPSGPESSSVQRQIYRALLIRVSDGWEKNPADFEPYHLKLEECMSAEQIPSTEHIQGYVKKQIQDAADQGIIFVGFIQEPAGLRPHALQLGEPEEASLSLHSSPSSLHGSGLTPCPSPLEEPEPEPNPELGDESGAENQEQKQGGEALKAGGDAGGDENSETLTHNNNDTDKSTDTSQKTSRLALNKSGAELFGLFNYPGRRSAQLKYYTVKVPLRVQTQSDGIWSLEANWLDHMTQHFNNGASLVDGYFQINNHNNDVLVKTVDSVFVFQEGVEGDTNSAAAYDAIVVEQWTIIDGLEVKTDYIPLLQSLASFGWRLTCVLPTPITKTNSDGSLATKQIVFLQRPVLPRKKKESKKVIFKARNKSNKNSVKDAPKNKKKKDSTPTVEKEISDQKAERSVEDTNTSVNERRPEKQNNEADAQVQSQQKQDTEEGKWAEEVTAAGSEVGGEKQDEVSGNSEKDEGAKDEVDGKAEEQSVKIEAETGSCKDQKGDDEGDKPDEPSANQD", "length": 590, "header": "tr|A0AB32T607-1|A0A8M9NZW7_DANRE Computationally mapped isoform of Raftlin isoform X1 OS=Danio rerio OX=7955 GN=rftn1b PE=3 SV=1 CANONICAL=A0A8M9NZW7-1" }, "locus": {} }, { "isoform_ac": "A0AB32T8W4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW7/entry#A0AB32T8W4-1", "sequence": { "sequence": "MGCGLRKLRQTEDNSPGKIYSTLKRPQVETKTGVSYTYSHLDFVVGKDADGTSSLCLSSVRDLPSQLQDLYQQGFILTAVHPFIHPSGPESSSVQRQIYRALLIRVSDGWEKNPADFEPYHLKLEECMSAEQIPSTEHIQGYVKKIQDAADQGIIFVGFIQEPAGLRPHALQLGEPEEASLSLHSSPSSLHGSGLTPCPSPLEEPEPEPNPELGDESGAENQEQKQGGEALKAGGDAGGDENSETLTHNNNDTDKSTDTSQKTSRLALNKSGAELFGLFNYPGRRSAQLKYYTVKVPLRVQTQSDGIWSLEANWLDHMTQHFNNGASLVDGYFQINNHNNDVLVKTVDSVFVFQEGVEGDTNSAAAYDAIVVEQWTIIDGLEVKTDYIPLLQSLASFGWRLTCVLPTPITKTNSDGSLATKQIVFLQRPVLPRKKKESKKVIFKARNKSNKNSVKDAPKNKKKKDSTPTVEKEISDQKAERSVEDTNTSVNERRPEKQNNEADAQVQSQQKQDTEEGKWAEEVTAAGSEVGGEKQDEVSGNSEKDEGAKDEVDGKAEEQSVKIEAETGSCKDQKGDDEGDKPDEPSANQD", "length": 590, "header": "tr|A0AB32T8W4-1|A0A8M9NZW7_DANRE Computationally mapped isoform of Raftlin isoform X1 OS=Danio rerio OX=7955 GN=rftn1b PE=3 SV=1 CANONICAL=A0A8M9NZW7-1" }, "locus": {} }, { "isoform_ac": "A0AC58HLM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW7/entry#A0AC58HLM1-1", "sequence": { "sequence": "MGCGLRKLRQTEDNSPGKIYSTLKRPQVETKTGVSYTYSHLDFVVGKDDGTSSLCLSSVRDLPSQLQDLYQQGFILTAVHPFIHPSGPESSSVQRQIYRALLIRVSDGWEKNPADFEPYHLKLEECMSAEQIPSTEHIQGYVKKIQDAADQGIIFVGFIQEPAGLRPHALQLGEPEEASLSLHSSPSSLHGSGLTPCPSPLEEPEPEPNPELGDESGAENQEQKQGGEALKAGGDAGGDENSETLTHNNNDTDKSTDTSQKTSRLALNKSGAELFGLFNYPGRRSAQLKYYTVKVPLRVQTQSDGIWSLEANWLDHMTQHFNNGASLVDGYFQINNHNNDVLVKTVDSVFVFQEGVEGDTNSAAAYDAIVVEQWTIIDGLEVKTDYIPLLQSLASFGWRLTCVLPTPITKTNSDGSLATKQIVFLQRPVLPRKKKESKKVIFKARNKSNKNSVKDAPKNKKKKDSTPTVEKEISDQKAERSVEDTNTSVNERRPEKQNNEADAQVQSQQKQDTEEGKWAEEVTAAGSEVGGEKQDEVSGNSEKDEGAKDEVDGKAEEQSVKIEAETGSCKDQKGDDEGDKPDEPSANQD", "length": 589, "header": "tr|A0AC58HLM1-1|A0AC58HLM1_DANRE Computationally mapped isoform of Raftlin isoform X4 OS=Danio rerio OX=7955 GN=rftn1b PE=3 SV=1 CANONICAL=A0A8M9NZW7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885083", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885083", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZW7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], 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The reference sequence was derived from JBMGRA010000019.1. On Sep 16, 2025 this sequence version replaced XP_021323879.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001430378", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430378" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGS7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGS7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101885796", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGS7", "locus": {} } ], "crossref": [ { "id": "A0A8M9PGS7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PGS7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03590", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03590", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101885796", "url": 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"id": "dre:101885796", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885796", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PGS7", "url": "https://www.orthodb.org/?gene=A0A8M9PGS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45710", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45710", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45710:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45710:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001430378", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430378", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PGS7", "url": 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"count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P4H9-1", "uniprot_ac": "A0A8M9P4H9", "uniprot_id": "A0A8M9P4H9_DANRE", "mass": { "chemical_mass": 37282.0, "monoisotopic_mass": 37282.0 }, "refseq": { "ac": "XP_009294052", "name": "BTB/POZ domain-containing protein KCTD20 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294052" }, "gene_names": [ { "name": "kctd20", "type": "recommended", "evidence": [ { "id": "A0A8M9P4H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4H9" } ] }, { "name": "kctd20", "type": "synonym", "evidence": [ { "id": "XP_009294052", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294052" } ] } ], "protein_names": [ { "name": "BTB/POZ domain-containing protein KCTD20 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_009294052", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294052" }, { "id": "A0A8M9P4H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4H9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009294052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294052" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4H9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4H9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "kctd20", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4H9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100408-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100408-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "570693", "url": "https://www.ncbi.nlm.nih.gov/gene/570693", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039885", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039885", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039886", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570693", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570693", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P4H9", "url": "https://www.orthodb.org/?gene=A0A8M9P4H9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21637", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21637", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21637:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21637:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009294052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009294052", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P4H9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P4H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4H9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T9C0", "url": "https://www.uniprot.org/uniprotkb/A0AB32T9C0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T9C0-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T9C0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100408-1", "url": "https://zfin.org/ZDB-GENE-100408-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAEEHATARGMTVGAEGGADVTKGVWPAQPRPLSHDRVTLVVDGTHFVVDPAVFTAYPDTVLGRMFGRARQHSFTRPNTKGEYEIAEGIGASIFRIILDFYRVGILHCPEGVSLAELREACDYLCINFDYNTVRCRDLSALLHELSNDGARRQFEVFLEELLLPAMVSSAQEGERECHIVVLTDDDTVDWDHDNPPPMGEEHSQIIYSTKLYRFFKFIENRDVAKAHLKERGLKNIRIGIEGYPTCKEKVKRRPGGKSEVIYSYLQRPFIQLSWEKEEGKSRHVDFQCVRSRSVPNLITAMGEGPTRAGATPTPQVDELDRLNGPAPPGLDQ", "length": 332, "header": "tr|A0A8M9P4H9-1|A0A8M9P4H9_DANRE Isoform 1 of BTB/POZ domain-containing protein KCTD20 isoform X1 OS=Danio rerio OX=7955 GN=kctd20 PE=4 SV=1 CANONICAL=A0A8M9P4H9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P4H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4H9/entry#A0A8M9P4H9-1", "sequence": { "sequence": "MAEEHATARGMTVGAEGGADVTKGVWPAQPRPLSHDRVTLVVDGTHFVVDPAVFTAYPDTVLGRMFGRARQHSFTRPNTKGEYEIAEGIGASIFRIILDFYRVGILHCPEGVSLAELREACDYLCINFDYNTVRCRDLSALLHELSNDGARRQFEVFLEELLLPAMVSSAQEGERECHIVVLTDDDTVDWDHDNPPPMGEEHSQIIYSTKLYRFFKFIENRDVAKAHLKERGLKNIRIGIEGYPTCKEKVKRRPGGKSEVIYSYLQRPFIQLSWEKEEGKSRHVDFQCVRSRSVPNLITAMGEGPTRAGATPTPQVDELDRLNGPAPPGLDQ", "length": 332, "header": "tr|A0A8M9P4H9-1|A0A8M9P4H9_DANRE Isoform 1 of BTB/POZ domain-containing protein KCTD20 isoform X1 OS=Danio rerio OX=7955 GN=kctd20 PE=4 SV=1 CANONICAL=A0A8M9P4H9-1" }, "locus": {} }, { "isoform_ac": "A0AB32T9C0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4H9/entry#A0AB32T9C0-1", "sequence": { "sequence": "MTVGAEGGADVTKGVWPAQPRPLSHDRVTLVVDGTHFVVDPAVFTAYPDTVLGRMFGRARQHSFTRPNTKGEYEIAEGIGASIFRIILDFYRVGILHCPEGVSLAELREACDYLCINFDYNTVRCRDLSALLHELSNDGARRQFEVFLEELLLPAMVSSAQEGERECHIVVLTDDDTVDWDHDNPPPMGEEHSQIIYSTKLYRFFKFIENRDVAKAHLKERGLKNIRIGIEGYPTCKEKVKRRPGGKSEVIYSYLQRPFIQLSWEKEEGKSRHVDFQCVRSRSVPNLITAMGEGPTRAGATPTPQVDELDRLNGPAPPGLDQ", "length": 322, "header": "tr|A0AB32T9C0-1|A0A8M9P4H9_DANRE Computationally mapped isoform of BTB/POZ domain-containing protein KCTD20 isoform X1 OS=Danio rerio OX=7955 GN=kctd20 PE=4 SV=1 CANONICAL=A0A8M9P4H9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 306, "start_aa": "Thr", "end_pos": 306, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr306", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 313, "start_aa": "Thr", "end_pos": 313, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr313", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:570693", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570693", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0U1RRY2-1", "protein_name": "Potassium channel tetramerization domain containing 20", "gene_name": "Kctd20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNVHQGSDGDWLLQPELSFLGDETLAATQEKESSSLVSSGLPSLTYPLAARNEDFALDSAPQPAASLQHPHIMPLPEDNKGSCFQSGSRRSREPFLVPERSGSGGLGFGGSSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGEDVLEDQEIMMHHPPQVDELDRLNAPLAQMAPNDFQD", "length": 418 }, "evidence": [ { "id": "RGD:1309887", "url": "https://alliancegenome.org/gene/RGD:1309887#orthology", "database": "AGR" }, { "id": "HGNC:21052", "url": "https://alliancegenome.org/gene/HGNC:21052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100408-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100408-1#orthology", "database": "AGR" }, { "id": "MGI:1914239", "url": "https://alliancegenome.org/gene/MGI:1914239#orthology", "database": "AGR" }, { "id": "FB:FBgn0035107", "url": "https://alliancegenome.org/gene/FB:FBgn0035107#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M2BAC2-1", "protein_name": "BTB/POZ domain-containing protein 10a isoform X1", "gene_name": "btbd10a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPEDVKSPGKPWLGEGARVLCAFIHQLLPCCFVLKRGGGQPRGAHLEGDLLNMSLHGASGGAGALEQHRERRRSGDRSRDSSHDRGEGQLTPCIRNVTSPIRQTLGERERDSGCSSRSTSPRPQKACSSSLFYTDSHGKTHSSDMIYVCENLKEGPRSLRTAERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGISSTVFRAILDYYKSGIIRCPDGISIPELREACDYLCIAFDYSTIKCRDLSALMHELSNDGARRQFEFYLEEMVLPLMVASAQSGERECHVVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPGPQVDELDILPNHPQPSQHYEPDPDASSPAI", "length": 472 }, "evidence": [ { "id": "FB:FBgn0035107", "url": "https://alliancegenome.org/gene/FB:FBgn0035107#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F7EZ61-1", "protein_name": "BTB domain containing 10", "gene_name": "Btbd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRPHPYDSNSSDPENWDRKLHSRPRKLYKHSSTASRVAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQHHIEREKDHSSSRPSSPRPQRASPNGSISSAGNSSRNSSQSSSDGSCKASGEMVFVYENAKEGARSVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDSLPSHPASGNNDLDPDAQNPML", "length": 475 }, "evidence": [ { "id": "FB:FBgn0035107", "url": "https://alliancegenome.org/gene/FB:FBgn0035107#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0E8K5-1", "protein_name": "Mrityu, isoform A", "gene_name": "mri", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSNTPSLNSSSSNISSKAPLAQKQDTYSSDSSEEVLETAEERRRRILKERSRLNRPQHNMSGGGAVPKHDIKSPCGASPSCQATGSGMGRLPLPPERITMLVDGVRFTVEQSLLTAHPTTMLGTMFGSGFQFAHTNERGEYDVADGISHLVFRAILEYYKSGVIRCPPTVSVPELKEACDYLLIPFDATTVRCQNLRGLLHELSNEGARQQFELFLEDLILPLMVASAQRGDRECHVVVLLEDDMVEWDEEFPPQMGEEYCQTVHSTAMHRFFKYIENRDVAKQVMKDRGLKKIRCGIEGYPTHKEKIRRRPGGRAEVIYSYVQRPFIHMSWEKEEAKSRHVDFQCVKSKSVTNLAEANADPPLELDASGNPIPPIAVANPHPNNAELAAGMAVAPAAIGVAGPAVVVAVDEAAGGVVMLNELDQAAIAVAVGIVDENM", "length": 439 }, "evidence": [ { "id": "RGD:1309887", "url": "https://alliancegenome.org/gene/RGD:1309887#orthology", "database": "AGR" }, { "id": "HGNC:21052", "url": "https://alliancegenome.org/gene/HGNC:21052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100408-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100408-1#orthology", "database": "AGR" }, { "id": "MGI:1914239", "url": "https://alliancegenome.org/gene/MGI:1914239#orthology", "database": "AGR" }, { "id": "FB:FBgn0035107", "url": "https://alliancegenome.org/gene/FB:FBgn0035107#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7Z5Y7-1", "protein_name": "BTB/POZ domain-containing protein KCTD20", "gene_name": "KCTD20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNVHRGSDSDRLLRQEASCLVDDTLAVAQEKEANSLASSGPHNLTYPLGPRNEDLSLDYASQPANLQFPHIMPLAEDIKGSCFQSGNKRNHEPFIAPERFGNSSVGFGSNSHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYEIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGDDVLEDQEILMHHPPQVDELDRLNAPLSQMASNDFQD", "length": 419 }, "evidence": [ { "id": "RGD:1309887", "url": "https://alliancegenome.org/gene/RGD:1309887#orthology", "database": "AGR" }, { "id": "HGNC:21052", "url": "https://alliancegenome.org/gene/HGNC:21052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100408-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100408-1#orthology", "database": "AGR" }, { "id": "MGI:1914239", "url": "https://alliancegenome.org/gene/MGI:1914239#orthology", "database": "AGR" }, { "id": "FB:FBgn0035107", "url": "https://alliancegenome.org/gene/FB:FBgn0035107#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80X66-1", "protein_name": "BTB/POZ domain-containing protein 10", "gene_name": "Btbd10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGRPHPYDSNSSDPENWDRKLHSRPRKLYKHSSSASRVAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERAESQLTPCIRNVTSPTRQHHIEREKDHSSSRPSSPRPQRASPNGSMSSAGNSSRNSSQSSSDGSCKTSGEMVFVYENAKEGARNVRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPSHPASGNNDLDPDAQNPML", "length": 475 }, "evidence": [ { "id": "FB:FBgn0035107", "url": "https://alliancegenome.org/gene/FB:FBgn0035107#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDD8-1", "protein_name": "BTB/POZ domain-containing protein KCTD20", "gene_name": "Kctd20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVHQGSDGDWSLQPELSCLGDEALAATQEKEGSSLVSSGLHSVTYPLAARSEDLALDYASQPASLPHPHIMPLPEDNKGSCFQSGSKRSHEPFIVPERFGNSGLGFGGGAHSQAPEKVTLLVDGTRFVVNPQIFTAHPDTMLGRMFGPGREYNFTRPNEKGEYVIAEGISATVFRTVLDYYKTGIINCPDGISIPDLRDTCDYLCINFDFNTIRCQDLSALLHELSNDGAHKQFDHYLEELILPIMVGCAKKGERECHIVVLTDEDSVDWDEDHPPPMGEEYSQILYSSKLYRFFKYIENRDVAKTVLKERGLKNIRIGIEGYPTCKEKIKRRPGGRSEVIYNYVQRPFIQMSWEKEEGKSRHVDFQCVRSKSLTNLVAAGEDVLEDQEIIMHHPPQVDELDRLNAPLSQMAPNDFQD", "length": 419 }, "evidence": [ { "id": "RGD:1309887", "url": "https://alliancegenome.org/gene/RGD:1309887#orthology", "database": "AGR" }, { "id": "HGNC:21052", "url": "https://alliancegenome.org/gene/HGNC:21052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100408-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100408-1#orthology", "database": "AGR" }, { "id": "MGI:1914239", "url": "https://alliancegenome.org/gene/MGI:1914239#orthology", "database": "AGR" }, { "id": "FB:FBgn0035107", "url": "https://alliancegenome.org/gene/FB:FBgn0035107#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BSF8-1", "protein_name": "BTB/POZ domain-containing protein 10", "gene_name": "BTBD10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGRPHPYDGNSSDPENWDRKLHSRPRKLYKHSSTSSRIAKGGVDHTKMSLHGASGGHERSRDRRRSSDRSRDSSHERTESQLTPCIRNVTSPTRQHHVEREKDHSSSRPSSPRPQKASPNGSISSAGNSSRNSSQSSSDGSCKTAGEMVFVYENAKEGARNIRTSERVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGIGSTVFRAILDYYKTGIIRCPDGISIPELREACDYLCISFEYSTIKCRDLSALMHELSNDGARRQFEFYLEEMILPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKERGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMHPTPQVDELDILPIHPPSGNSDLDPDAQNPML", "length": 475 }, "evidence": [ { "id": "FB:FBgn0035107", "url": "https://alliancegenome.org/gene/FB:FBgn0035107#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "X1WDG9-1", "protein_name": "BTB/POZ domain-containing protein 10", "gene_name": "btbd10b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNMHGASGGCDRSRDRRRSSDRSRDSSHERGEGQLTPCIRNVTSPTRQHNSEREGGSSRPSSPRPQRISPSSSSSSGVASSRNSSLSSSEGTYKSMVPGEMVFVYENVKDGTRSVRTSEKVTLIVDNTRFVVDPSIFTAQPNTMLGRMFGSGREHNFTRPNEKGEYEVAEGISSTVFRAILDYYKSGIIRCPDGISIPELREACDYLCISFDYSTIKCRDLSALMHELSNDGARRQFEFYLEEMVLPLMVASAQSGERECHIVVLTDDDVVDWDEEYPPQMGEEYSQIIYSTKLYRFFKYIENRDVAKSVLKDRGLKKIRLGIEGYPTYKEKVKKRPGGRPEVIYNYVQRPFIRMSWEKEEGKSRHVDFQCVKSKSITNLAAAAADIPQDQLVVMNPGPQVDELDILPNHPPPGHHYSNNFNNEPDSDAPSPAV", "length": 434 }, "evidence": [ { "id": "FB:FBgn0035107", "url": "https://alliancegenome.org/gene/FB:FBgn0035107#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4H9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4H9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P4H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4H9" }, { "id": "SM00225", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 141, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 306, 313 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PBJ7-1", "uniprot_ac": "A0A8M9PBJ7", "uniprot_id": "A0A8M9PBJ7_DANRE", "mass": { "chemical_mass": 61288.0, "monoisotopic_mass": 61288.0 }, "refseq": { "ac": "XP_021324022", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324022" }, "gene_names": [ { "name": "si:ch211-51a19.5", "type": "recommended", "evidence": [ { "id": "A0A8M9PBJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBJ7" } ] }, { "name": "si:ch211-51a19.5", "type": "synonym", "evidence": [ { "id": "XP_021324022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324022" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PBJ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBJ7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021324022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324022" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324022" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBJ7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-51a19.5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBJ7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041014-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-366", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000094668", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000094668", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100034589", "url": "https://www.ncbi.nlm.nih.gov/gene/100034589", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100034589", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100034589", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ITIAIKA", "url": "https://omabrowser.org/oma/group/ITIAIKA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PBJ7", "url": "https://www.orthodb.org/?gene=A0A8M9PBJ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q5TZ48", "url": "https://www.orthodb.org/?gene=Q5TZ48", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31025", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31025", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31025:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31025:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_021324022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PBJ7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PBJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TA15", "url": "https://www.uniprot.org/uniprotkb/A0AB32TA15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TA15-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TA15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TAA6", "url": "https://www.uniprot.org/uniprotkb/A0AB32TAA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TAA6-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TAA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TBQ2", "url": "https://www.uniprot.org/uniprotkb/A0AB32TBQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TBQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TBQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TZ48", "url": "https://www.uniprot.org/uniprotkb/Q5TZ48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q5TZ48-1", "url": "https://www.uniprot.org/uniprotkb/Q5TZ48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041014-366", "url": "https://zfin.org/ZDB-GENE-041014-366", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLVKVQYQGVKKYVKLLTDFTFQYFISEVKSKFGLPTTADLQVFDDTDTNVEEDIFHELMESSPHVCLTVRCLEENMSAGLPEVISPTRSSTASTCTDTVSLSSTDHDDPEQPMQNQMTRASRCLMVDAERAKRIVQDALEKQSGGDEVLDEYKATKTLKHSTRRQLVNIVVSHMTEIHGRIPTRKQRETYALGIISLFPSLRDPFSAKGYVRICLSILNTNMFVCFNYLKEHFYDPEKGTGFIAWRLKTLSRKNPKRVRLEVSEVGGPSLKRRIDTGQQLEGDACREAISFLVHTADESEVLLKMKETFKRRQELVHDPKKSADILNIFPRFLDVKGLINQDFGLLFNAETSNKLLERWETSFKHKIINEAKSLTSTAEIRGLINSAEGQGSENDWDSDMSAVLLLLHLLPPSSGRKRTKISPTEAVERLVHFHKSCTSIEGHLSKREGHQPYLLGTGRIKGRIDNFYVVMDKHLIPCAGTSSLSAVDELFKIHYVFNLTYEEALVNIFTFLQTTVYNIDVGLTSESPRVKELRAKILN", "length": 540, "header": "tr|A0A8M9PBJ7-1|A0A8M9PBJ7_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-51a19.5 PE=4 SV=1 CANONICAL=A0A8M9PBJ7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PBJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBJ7/entry#A0A8M9PBJ7-1", "sequence": { "sequence": "MLVKVQYQGVKKYVKLLTDFTFQYFISEVKSKFGLPTTADLQVFDDTDTNVEEDIFHELMESSPHVCLTVRCLEENMSAGLPEVISPTRSSTASTCTDTVSLSSTDHDDPEQPMQNQMTRASRCLMVDAERAKRIVQDALEKQSGGDEVLDEYKATKTLKHSTRRQLVNIVVSHMTEIHGRIPTRKQRETYALGIISLFPSLRDPFSAKGYVRICLSILNTNMFVCFNYLKEHFYDPEKGTGFIAWRLKTLSRKNPKRVRLEVSEVGGPSLKRRIDTGQQLEGDACREAISFLVHTADESEVLLKMKETFKRRQELVHDPKKSADILNIFPRFLDVKGLINQDFGLLFNAETSNKLLERWETSFKHKIINEAKSLTSTAEIRGLINSAEGQGSENDWDSDMSAVLLLLHLLPPSSGRKRTKISPTEAVERLVHFHKSCTSIEGHLSKREGHQPYLLGTGRIKGRIDNFYVVMDKHLIPCAGTSSLSAVDELFKIHYVFNLTYEEALVNIFTFLQTTVYNIDVGLTSESPRVKELRAKILN", "length": 540, "header": "tr|A0A8M9PBJ7-1|A0A8M9PBJ7_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-51a19.5 PE=4 SV=1 CANONICAL=A0A8M9PBJ7-1" }, "locus": {} }, { "isoform_ac": "A0AB32TA15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBJ7/entry#A0AB32TA15-1", "sequence": { "sequence": "MLVKVQYQGVKKYVKLLTDFTFQYFISEVKSKFGLPTTADLQVFDDTDTNVEEDIFHELMESSPHVCLTVRCLEENMSAGLPEVISPTRSSTASTCTDTVSLSSTDHDDPEQPMQNQMTRASRCLMVDAERAKRIVQDALEKQSGGDEVLDEYKATKTLKHSTRRQLVNIVVSHMTEIHGRIPTRKQRETYALGIISLFPSLRDPFSAKGYEHFYDPEKGTGFIAWRLKTLSRKNPKRVRLEVSEVGGPSLKRRIDTGQQLEGDACREAISFLVHTADESEVLLKMKETFKRRQELVHDPKKSADILNIFPRFLDVKGLINQDFGLLFNAETSNKLLERWETSFKHKIINEAKSLTSTAEIRGLINSAEGQGSENDWDSDMSAVLLLLHLLPPSSGRKRTKISPTEAVERLVHFHKSCTSIEGHLSKREGHQPYLLGTGRIKGRIDNFYVVMDKHLIPCAGTSSLSAVDELFKIHYVFNLTYEEALVNIFTFLQTTVYNIDVGLTSESPRVKELRAKILN", "length": 520, "header": "tr|A0AB32TA15-1|A0A8M9PBJ7_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-51a19.5 PE=4 SV=1 CANONICAL=A0A8M9PBJ7-1" }, "locus": {} }, { "isoform_ac": "A0AB32TAA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBJ7/entry#A0AB32TAA6-1", "sequence": { "sequence": "MESSPHVCLTVRCLEENMSAGLPEVISPTRSSTASTCTDTVSLSSTDHDDPEQPMQNQMTRASRCLMVDAERAKRIVQDALEKQSGGDEVLDEYKATKTLKHSTRRQLVNIVVSHMTEIHGRIPTRKQRETYALGIISLFPSLRDPFSAKGYVRICLSILNTNMFVCFNYLKEHFYDPEKGTGFIAWRLKTLSRKNPKRVRLEVSEVGGPSLKRRIDTGQQLEGDACREAISFLVHTADESEVLLKMKETFKRRQELVHDPKKSADILNIFPRFLDVKGLINQDFGLLFNAETSNKLLERWETSFKHKIINEAKSLTSTAEIRGLINSAEGQGSENDWDSDMSAVLLLLHLLPPSSGRKRTKISPTEAVERLVHFHKSCTSIEGHLSKREGHQPYLLGTGRIKGRIDNFYVVMDKHLIPCAGTSSLSAVDELFKIHYVFNLTYEEALVNIFTFLQTTVYNIDVGLTSESPRVKELRAKILN", "length": 481, "header": "tr|A0AB32TAA6-1|A0A8M9PBJ7_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-51a19.5 PE=4 SV=1 CANONICAL=A0A8M9PBJ7-1" }, "locus": {} }, { "isoform_ac": "A0AB32TBQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBJ7/entry#A0AB32TBQ2-1", "sequence": { "sequence": "MESSPHVCLTVRCLEENMSAGLPEVISPTRSSTASTCTDTVSLSSTDHDDPEQPMQNQMTRASRCLMVDAERAKRIVQDALEKQSGGDEVLDEYKATKTLKHSTRRQLVNIVVSHMTEIHGRIPTRKQRETYALGIISLFPSLRDPFSAKGYEHFYDPEKGTGFIAWRLKTLSRKNPKRVRLEVSEVGGPSLKRRIDTGQQLEGDACREAISFLVHTADESEVLLKMKETFKRRQELVHDPKKSADILNIFPRFLDVKGLINQDFGLLFNAETSNKLLERWETSFKHKIINEAKSLTSTAEIRGLINSAEGQGSENDWDSDMSAVLLLLHLLPPSSGRKRTKISPTEAVERLVHFHKSCTSIEGHLSKREGHQPYLLGTGRIKGRIDNFYVVMDKHLIPCAGTSSLSAVDELFKIHYVFNLTYEEALVNIFTFLQTTVYNIDVGLTSESPRVKELRAKILN", "length": 461, "header": "tr|A0AB32TBQ2-1|A0A8M9PBJ7_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-51a19.5 PE=4 SV=1 CANONICAL=A0A8M9PBJ7-1" }, "locus": {} }, { "isoform_ac": "Q5TZ48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBJ7/entry#Q5TZ48-1", "sequence": { "sequence": "MESSPHVCLTVRCLEENMSAGLPEVISPTRSSTASTCTDTVSLSSTDHDDPEQPMQNQMTRASRCLMVDAERAKRIVQDALEKQSGGDEVLDEYKATKTLKHSTRRQLVNIVVSHMTEIHGRIPTRKQRETYALGIISLFPSLRDPFSAKGYINQDFGLLFNAETSNKLLERWETSFKHKIINEAKSLTSTAEIRGLINSAEGQGSENGRKRTKISPTEAVERLVHFHKSCTSIEGHLSKREGHQPYLLGTGRIKGRIDNFYVVMDKHLIPCAGTSSLSAVDELFKIHYVFNLTYEEALVNIFTFLQTTVYNIDVGLTSESPRVKELRAKILN", "length": 333, "header": "tr|Q5TZ48-1|A0A8M9PBJ7_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-51a19.5 PE=4 SV=1 CANONICAL=A0A8M9PBJ7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "Q5TZ48", "url": "https://www.uniprot.org/uniprotkb/Q5TZ48" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100034589", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100034589", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 499, "end_pos": 501 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PIL2-1", "uniprot_ac": "A0A8M9PIL2", "uniprot_id": "A0A8M9PIL2_DANRE", "mass": { "chemical_mass": 50141.0, "monoisotopic_mass": 50141.0 }, "refseq": { "ac": "XP_021322071", "name": "uncharacterized protein si:ch211-209f23.7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322071" }, "gene_names": [ { "name": "si:ch211-209f23.7", "type": "recommended", "evidence": [ { "id": "A0A8M9PIL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIL2" } ] }, { "name": "si:ch211-209f23.7", "type": "synonym", "evidence": [ { "id": "XP_021322071", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322071" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch211-209f23.7 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PIL2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIL2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch211-209f23.7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322071", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322071" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021322071.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322071", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322071" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIL2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-209f23.7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIL2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141211-48", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141211-48", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PIL2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PIL2", "database": "AlphaFoldDB", "categories": [] }, { "id": "798805", "url": "https://www.ncbi.nlm.nih.gov/gene/798805", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:798805", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798805", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_021322071", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322071", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PIL2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TBT5", "url": "https://www.uniprot.org/uniprotkb/A0AB32TBT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TBT5-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TBT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HY23", "url": "https://www.uniprot.org/uniprotkb/A0AC58HY23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HY23-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HY23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-141211-48", "url": "https://zfin.org/ZDB-GENE-141211-48", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MANNELNMEITSTTVMEKPKKNWRLKLPSFLKPARKNKIFRRQKETFKQTSDYEVEEDEGTTKRKKSKVGNFLKAARKLFRMSCFGQTEEQLSDPADSDDDILCPSESDQSLEVALVITHNHEESCVNDDLKVDEKDDMKTHNTEHVNKEEEVEEMRMNDEKDKEEKIKKRRRRKKNSKMKEEEEKKEEEVVKEEMKIKEESLKENEEEDKNEKEMKVKEEKMKDDEEENNEEEMKIKEESLKENEEEEEDKNEKEIKVKEEKMKDDEEENNEEEMKIKEESLKENEEEEVEDKNEKEMKVKQEKMKDEEEENENMKKRMRRRKRNNRIKEEKKEEKLIEKEMEVKRMEENEEKEMDKNEEEMKEEETEEEEEEKKPKEEKRKRSKKRDSRKSRRMMRRRSKRRRLGRV", "length": 409, "header": "tr|A0A8M9PIL2-1|A0A8M9PIL2_DANRE Isoform 1 of Uncharacterized protein si:ch211-209f23.7 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-209f23.7 PE=4 SV=2 CANONICAL=A0A8M9PIL2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PIL2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIL2/entry#A0A8M9PIL2-1", "sequence": { "sequence": "MANNELNMEITSTTVMEKPKKNWRLKLPSFLKPARKNKIFRRQKETFKQTSDYEVEEDEGTTKRKKSKVGNFLKAARKLFRMSCFGQTEEQLSDPADSDDDILCPSESDQSLEVALVITHNHEESCVNDDLKVDEKDDMKTHNTEHVNKEEEVEEMRMNDEKDKEEKIKKRRRRKKNSKMKEEEEKKEEEVVKEEMKIKEESLKENEEEDKNEKEMKVKEEKMKDDEEENNEEEMKIKEESLKENEEEEEDKNEKEIKVKEEKMKDDEEENNEEEMKIKEESLKENEEEEVEDKNEKEMKVKQEKMKDEEEENENMKKRMRRRKRNNRIKEEKKEEKLIEKEMEVKRMEENEEKEMDKNEEEMKEEETEEEEEEKKPKEEKRKRSKKRDSRKSRRMMRRRSKRRRLGRV", "length": 409, "header": "tr|A0A8M9PIL2-1|A0A8M9PIL2_DANRE Isoform 1 of Uncharacterized protein si:ch211-209f23.7 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-209f23.7 PE=4 SV=2 CANONICAL=A0A8M9PIL2-1" }, "locus": {} }, { "isoform_ac": "A0AB32TBT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIL2/entry#A0AB32TBT5-1", "sequence": { "sequence": "MEITSTTVMEKPKKNRRLKLPSFLKPARKNKIFRRQKETPQQTPDIGNNYEVEEDEGTTKRKKSKVGNFLKAARKLFRMSCFGQTEEQLSDPADSDDDILCPSESDQSLEVALVITHNHEESCVNDDLKVDEKDDMKTHNTEHVNKEEEVEEMRMNDEKDKEEKIKKRRRRKRNSKMKEEEEKQEEEVVKEEMKIKEESLKENEEEEDKNEKEIKVKEEKMKDDEEENNEEEMKIKEESLKENEEEEVEDKNEKEMKVKQEKMKDEEEENENMKKRMRRRKRNNRIKEEKKEEKLIEKEMEVKRMEENEEKEMDKNEEEMKEEETEEEEEEKKPKEEKRKRSKKRDSRKSRRMMRRRSKRRRLGRV", "length": 366, "header": "tr|A0AB32TBT5-1|A0A8M9PIL2_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-209f23.7 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-209f23.7 PE=4 SV=1 CANONICAL=A0A8M9PIL2-1" }, "locus": {} }, { "isoform_ac": "A0AC58HY23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIL2/entry#A0AC58HY23-1", "sequence": { "sequence": "MSCFGQTEEQLSDPADSDDDILCPSESDQSLEVALVITHNHEESCVNDDLKVDEKDDMKTHNTEHVNKEEEVEEMRMNDEKDKEEKIKKRRRRKRNSKMKEEEEKQEEEVVKEEMKIKEESLKENEEEEDKNEKEIKVKEEKMKDDEEENNEEEMKIKEESLKENEEEEVEDKNEKEMKVKQEKMKDEEEENENMKKRMRRRKRNNRIKEEKKEEKLIEKEMEVKRMEENEEKEMDKNEEEMKEEETEEEEEEKKPKEEKRKRSKKRDSRKSRRMMRRRSKRRRLGRV", "length": 288, "header": "tr|A0AC58HY23-1|A0AC58HY23_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-209f23.7 isoform X3 OS=Danio rerio OX=7955 GN=si:ch211-209f23.7 PE=4 SV=1 CANONICAL=A0A8M9PIL2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:798805", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798805", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PEC2-1", "uniprot_ac": "A0A8M9PEC2", "uniprot_id": "A0A8M9PEC2_DANRE", "mass": { "chemical_mass": 46368.0, "monoisotopic_mass": 46368.0 }, "refseq": { "ac": "XP_021325198", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325198" }, "gene_names": [ { "name": "LOC100148050", "type": "recommended", "evidence": [ { "id": "A0A8M9PEC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEC2" } ] }, { "name": "LOC100148050", "type": "synonym", "evidence": [ { "id": "XP_021325198", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325198" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PEC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEC2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325198", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325198" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021325198.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325198", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325198" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEC2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100148050", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEC2", "locus": {} } ], "crossref": [ { "id": "A0A8M9PEC2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PEC2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100148050", "url": "https://www.ncbi.nlm.nih.gov/gene/100148050", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100148050", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148050", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PEC2", "url": "https://www.orthodb.org/?gene=A0A8M9PEC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325198", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325198", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PEC2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PEC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TCV4", "url": "https://www.uniprot.org/uniprotkb/A0AB32TCV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TCV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TCV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IG19", "url": "https://www.uniprot.org/uniprotkb/A0AC58IG19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IG19-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IG19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFVLFFVPLLLDGVFSFMDVITSVPVKEGDSVTLYADAIEIQKADLILWTFGPDGTRIVQFNRMANKISLYEEILDGRFRDRLKLDSKTGSLTMRNTTVADSGLYKLELIGGKEVPPKKFKIIVSAPLSIPAVIRDPSSPSSSVQYCSVLCSVVNVSAVSLSWYKGNSVLSSISVSDLSISLSLPLEVEYQDKNTYSCVINNTISNQTTHLDINTLCQPFNGWSPNHTALVCVCIVPAVLCGLYFYHQHRISKRGNKTSNKNRENGTVPLLLVEADGRCTSGQEDDVEKSVFVKEDKITLMPVMEGETVTLQADATEIREIDLILWTFANFKGCSSANFVTIATLNKMNSNESVKQFRDTLKLDHTTGSLTITKMTAKHYGFYKLQMIRRGQMDFHTFSVFNVPEKKERRLYSV", "length": 415, "header": "tr|A0A8M9PEC2-1|A0A8M9PEC2_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100148050 PE=4 SV=2 CANONICAL=A0A8M9PEC2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PEC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEC2/entry#A0A8M9PEC2-1", "sequence": { "sequence": "MPFVLFFVPLLLDGVFSFMDVITSVPVKEGDSVTLYADAIEIQKADLILWTFGPDGTRIVQFNRMANKISLYEEILDGRFRDRLKLDSKTGSLTMRNTTVADSGLYKLELIGGKEVPPKKFKIIVSAPLSIPAVIRDPSSPSSSVQYCSVLCSVVNVSAVSLSWYKGNSVLSSISVSDLSISLSLPLEVEYQDKNTYSCVINNTISNQTTHLDINTLCQPFNGWSPNHTALVCVCIVPAVLCGLYFYHQHRISKRGNKTSNKNRENGTVPLLLVEADGRCTSGQEDDVEKSVFVKEDKITLMPVMEGETVTLQADATEIREIDLILWTFANFKGCSSANFVTIATLNKMNSNESVKQFRDTLKLDHTTGSLTITKMTAKHYGFYKLQMIRRGQMDFHTFSVFNVPEKKERRLYSV", "length": 415, "header": "tr|A0A8M9PEC2-1|A0A8M9PEC2_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100148050 PE=4 SV=2 CANONICAL=A0A8M9PEC2-1" }, "locus": {} }, { "isoform_ac": "A0AB32TCV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEC2/entry#A0AB32TCV4-1", "sequence": { "sequence": "MPFVLFFVPLLLDGVFSFMDVITSVPVKEGDSVTLYADAIEIQKADLILWTFGPDGTRIVQFNRMANKISLYEEILDGRFRDRLKLDSKTGSLTMRNTTVADSGLYKLELIGGKEVPPKKFKIIVSAPLSIPAVIRDPSSPSSSVQYCSVLCSVVNVSAVSLSWYKGNSVLSSISVSDLSISLSLPLEVEYQDKNTYSCVINNTISNQTTHLDINTLCQPFNGWSPNHTALVCVCIVPAVLCGLYFYHQHRISKRGNKTSNKNRENGTVPLLLVEADGVFVKEDKITLMPVMEGETVTLQADATEIREIDLILWTFANFKGCSSANFVTIATLNKMNSNESVKQFRDTLKLDHTTGSLTITKMTAKHYGFYKLQMIRRGQMDFHTFSVFNVPEKKERRLYSV", "length": 402, "header": "tr|A0AB32TCV4-1|A0A8M9PEC2_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100148050 PE=4 SV=1 CANONICAL=A0A8M9PEC2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IG19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEC2/entry#A0AC58IG19-1", "sequence": { "sequence": "MPFVLFFVPLLLDGVFSFMDVITSVPVKEGDSVTLYADAIEIQKADLILWTFGPDGTRIVQFNRMANKISLYEEILDGRFRDRLKLDSKTGSLTMRNTTVADSGLYKLELIGGKEVPPKKFKIIVSAPLSIPAVIRDPSSPSSSVQYCSVLCSVVNVSAVSLSWYKGNSVLSSISVSDLSISLSLPLEVEYQDKNTYSCVINNTISNQTTHLDINTLCQPFNGWSPNHTALVCVCIVPAVLCGLYFYHQHRISKRGNKTSNKNRENGTVPLLLVEADGEAGEITGGAGLHTVLR", "length": 294, "header": "tr|A0AC58IG19-1|A0AC58IG19_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=LOC100148050 PE=4 SV=1 CANONICAL=A0A8M9PEC2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100148050", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148050", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 266, "end_pos": 268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PEC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEC2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 215, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 }, { "start_pos": 202, "end_pos": 204 }, { "start_pos": 207, "end_pos": 209 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 266, "end_pos": 268 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PE09-1", "uniprot_ac": "A0A8M9PE09", "uniprot_id": "A0A8M9PE09_DANRE", "mass": { "chemical_mass": 56036.0, "monoisotopic_mass": 56036.0 }, "refseq": { "ac": "XP_021325068", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325068" }, "gene_names": [ { "name": "LOC110437709", "type": "recommended", "evidence": [ { "id": "A0A8M9PE09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09" } ] }, { "name": "LOC110437709", "type": "synonym", "evidence": [ { "id": "XP_021325068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325068" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PE09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325068", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325068" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325068", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325068" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE09", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0AB32TFA8", "url": "https://www.uniprot.org/uniprotkb/A0AB32TFA8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE09", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110437709", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09", "locus": {} } ], "crossref": [ { "id": "A0A8M9PE09", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PE09", "database": "AlphaFoldDB", "categories": [] }, { "id": "110437709", "url": "https://www.ncbi.nlm.nih.gov/gene/110437709", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110437709", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437709", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PE09", "url": "https://www.orthodb.org/?gene=A0A8M9PE09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24379:SF127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24379:SF127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325068", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325068", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PE09", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PE09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TFA8", "url": "https://www.uniprot.org/uniprotkb/A0AB32TFA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TFA8-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TFA8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLDQNSEKMSDPEPCGIKEEETEELIDVMVKEESEELSEDEEEHHVKSETETHSNTEHEKNTKSTDVVSFTCIQCGKSFTQKSDLRRHMMIHTGEKPYKCSHCDMRFSHSGNLTKHERTHTGEKPYHCTACGKNFSQSSSLRTHRKTIHKGMVEEREDVEKRRVRNKKKTPSKTESSVVMKRTPESFICGKCGMSFVRRYHLTLHMKIHFEEKPCKCSYCDKRFRDLKYLLRHESLHTGGNLFHCNVCGKGFTLSSSLRRHKKTIHNLDVKDEKVPRRVHKKEKSYLCSWCGKSLTQQSSLKIHERTHTGEKPYPCTLCEKSFICASHLRHHTMVHTGEKPHKCDQCSKTFVSASELKDHLRVHSKEKPFSCYLCEKSFNHRSNLRYHLKIHFGVKKHACLECGKTFVRAGELKQHQTTHTGEKSFTCPQCGKGFTQLSNIKKHMRIHSGERPHTCDQCSKAFLTASELRIHLRVHKKEKM", "length": 482, "header": "tr|A0A8M9PE09-1|A0A8M9PE09_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110437709 PE=3 SV=1 CANONICAL=A0A8M9PE09-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PE09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09/entry#A0A8M9PE09-1", "sequence": { "sequence": "MSLDQNSEKMSDPEPCGIKEEETEELIDVMVKEESEELSEDEEEHHVKSETETHSNTEHEKNTKSTDVVSFTCIQCGKSFTQKSDLRRHMMIHTGEKPYKCSHCDMRFSHSGNLTKHERTHTGEKPYHCTACGKNFSQSSSLRTHRKTIHKGMVEEREDVEKRRVRNKKKTPSKTESSVVMKRTPESFICGKCGMSFVRRYHLTLHMKIHFEEKPCKCSYCDKRFRDLKYLLRHESLHTGGNLFHCNVCGKGFTLSSSLRRHKKTIHNLDVKDEKVPRRVHKKEKSYLCSWCGKSLTQQSSLKIHERTHTGEKPYPCTLCEKSFICASHLRHHTMVHTGEKPHKCDQCSKTFVSASELKDHLRVHSKEKPFSCYLCEKSFNHRSNLRYHLKIHFGVKKHACLECGKTFVRAGELKQHQTTHTGEKSFTCPQCGKGFTQLSNIKKHMRIHSGERPHTCDQCSKAFLTASELRIHLRVHKKEKM", "length": 482, "header": "tr|A0A8M9PE09-1|A0A8M9PE09_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110437709 PE=3 SV=1 CANONICAL=A0A8M9PE09-1" }, "locus": {} }, { "isoform_ac": "A0AB32TFA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09/entry#A0AB32TFA8-1", "sequence": { "sequence": "MSDPEPCGIKEEETEELIDVMVKEESEELSEDEEEHHVKSETETHSNTEHEKNTKSTDVVSFTCIQCGKSFTQKSDLRRHMMIHTGEKPYKCSHCDMRFSHSGNLTKHERTHTGEKPYHCTACGKNFSQSSSLRTHRKTIHKGMVEEREDVEKRRVRNKKKTPSKTESSVVMKRTPESFICGKCGMSFVRRYHLTLHMKIHFEEKPCKCSYCDKRFRDLKYLLRHESLHTGGNLFHCNVCGKGFTLSSSLRRHKKTIHNLDVKDEKVPRRVHKKEKSYLCSWCGKSLTQQSSLKIHERTHTGEKPYPCTLCEKSFICASHLRHHTMVHTGEKPHKCDQCSKTFVSASELKDHLRVHSKEKPFSCYLCEKSFNHRSNLRYHLKIHFGVKKHACLECGKTFVRAGELKQHQTTHTGEKSFTCPQCGKGFTQLSNIKKHMRIHSGERPHTCDQCSKAFLTASELRIHLRVHKKEKM", "length": 473, "header": "tr|A0AB32TFA8-1|A0A8M9PE09_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110437709 PE=3 SV=1 CANONICAL=A0A8M9PE09-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110437709", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437709", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE09", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE09", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE09", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE09", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09" } ], "pmid": "" }, { "name": "double-stranded DNA binding", "id": "GO:0003690", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003690", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE09", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE09", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE09", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PE09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE09" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 71, "end_pos": 98, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 135, "end_pos": 137 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PC97-1", "uniprot_ac": "A0A8M9PC97", "uniprot_id": "A0A8M9PC97_DANRE", "mass": { "chemical_mass": 26421.0, "monoisotopic_mass": 26421.0 }, "refseq": { "ac": "XP_009289855", "name": "POU domain class 2-associating factor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289855" }, "gene_names": [ { "name": "pou2af1", "type": "recommended", "evidence": [ { "id": "A0A8M9PC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97" } ] }, { "name": "pou2af1", "type": "synonym", "evidence": [ { "id": "XP_009289855", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289855" } ] } ], "protein_names": [ { "name": "POU domain class 2-associating factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_009289855", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289855" }, { "id": "A0A8M9PC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009289855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289855" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "pou2af1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97", "locus": {} } ], "crossref": [ { "id": "103908823", "url": "https://www.ncbi.nlm.nih.gov/gene/103908823", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015389", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015389", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:103908823", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103908823", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SPIGQPC", "url": "https://omabrowser.org/oma/group/SPIGQPC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PC97", "url": "https://www.orthodb.org/?gene=A0A8M9PC97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15363", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15363", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15363:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15363:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09310", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09310", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009289855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009289855", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PC97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PC97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TGA1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TGA1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCA8", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCA8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCB3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCB3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCB7", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCB7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCB7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGKLVSEAPTSKPYQGVRVKDPVKELLRRKRGNAARSTATVMVPSNTLQSCTLAGTSTFAEVPQSGLNDSVVDVSGLCTGWIAQTTSTTALQPLSHWTPPDCQHHDPAIPSHADMYVQPICPGYTVVGSSPMLTFAHAPLFTNLATVSTSSSVLPQVEVPDSSLTYIPWAQPLSTIPGPVMQASSALSAPQLFPVPLTLPVLSPEPEPPQVEPQQAPEGTLALEKLLEDNEVHKESYICNSSLFAEDI", "length": 248, "header": "tr|A0A8M9PC97-1|A0A8M9PC97_DANRE Isoform 1 of POU domain class 2-associating factor 1 isoform X1 OS=Danio rerio OX=7955 GN=pou2af1 PE=4 SV=1 CANONICAL=A0A8M9PC97-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PC97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97/entry#A0A8M9PC97-1", "sequence": { "sequence": "MGKLVSEAPTSKPYQGVRVKDPVKELLRRKRGNAARSTATVMVPSNTLQSCTLAGTSTFAEVPQSGLNDSVVDVSGLCTGWIAQTTSTTALQPLSHWTPPDCQHHDPAIPSHADMYVQPICPGYTVVGSSPMLTFAHAPLFTNLATVSTSSSVLPQVEVPDSSLTYIPWAQPLSTIPGPVMQASSALSAPQLFPVPLTLPVLSPEPEPPQVEPQQAPEGTLALEKLLEDNEVHKESYICNSSLFAEDI", "length": 248, "header": "tr|A0A8M9PC97-1|A0A8M9PC97_DANRE Isoform 1 of POU domain class 2-associating factor 1 isoform X1 OS=Danio rerio OX=7955 GN=pou2af1 PE=4 SV=1 CANONICAL=A0A8M9PC97-1" }, "locus": {} }, { "isoform_ac": "A0AB32TGA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97/entry#A0AB32TGA1-1", "sequence": { "sequence": "MGKLVSEAPTSKPYQGVRVKDPVKELLRRKRGNAARSTATVMVPSNTLQSCTLAEVPQSGLNDSVVDVSGLCTGWIAQTTSTTALQPLSHWTPPDCQHHDPAIPSHADMYVQPICPGYTVVGSSPMLTFAHAPLFTNLATVSTSSSVLPQVEVPDSSLTYIPWAQPLSTIPGPVMQASSALSAPQLFPVPLTLPVLSPEPEPPQVEPQQAPEGTLALEKLLEDNEVHKESYICNSSLFAEDI", "length": 242, "header": "tr|A0AB32TGA1-1|A0A8M9PC97_DANRE Computationally mapped isoform of POU domain class 2-associating factor 1 isoform X1 OS=Danio rerio OX=7955 GN=pou2af1 PE=4 SV=1 CANONICAL=A0A8M9PC97-1" }, "locus": {} }, { "isoform_ac": "A0AC58HCA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97/entry#A0AC58HCA8-1", "sequence": { "sequence": "MVPSNTLQSCTLAEVPQSGLNDSVVDVSGLCTGWIAQTTSTTALQPLSHWTPPDCQHHDPAIPSHADMYVQPICPGYTVVGSSPMLTFAHAPLFTNLATVSTSSSVLPQVEVPDSSLTYIPWAQPLSTIPGPVMQASSALSAPQLFPVPLTLPVLSPEPEPPQVEPQQAPEGTLALEKLLEDNEVHKESYICNSSLFAEDI", "length": 201, "header": "tr|A0AC58HCA8-1|A0AC58HCA8_DANRE Computationally mapped isoform of POU domain class 2-associating factor 1 isoform X5 OS=Danio rerio OX=7955 GN=pou2af1 PE=4 SV=1 CANONICAL=A0A8M9PC97-1" }, "locus": {} }, { "isoform_ac": "A0AC58HCB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97/entry#A0AC58HCB3-1", "sequence": { "sequence": "MGKLSEAPTSKPYQGVRVKDPVKELLRRKRGNAARSTATVMVPSNTLQSCTLAGTSTFAEVPQSGLNDSVVDVSGLCTGWIAQTTSTTALQPLSHWTPPDCQHHDPAIPSHADMYVQPICPGYTVVGSSPMLTFAHAPLFTNLATVSTSSSVLPQVEVPDSSLTYIPWAQPLSTIPGPVMQASSALSAPQLFPVPLTLPVLSPEPEPPQVEPQQAPEGTLALEKLLEDNEVHKESYICNSSLFAEDI", "length": 247, "header": "tr|A0AC58HCB3-1|A0AC58HCB3_DANRE Computationally mapped isoform of POU domain class 2-associating factor 1 isoform X2 OS=Danio rerio OX=7955 GN=pou2af1 PE=4 SV=1 CANONICAL=A0A8M9PC97-1" }, "locus": {} }, { "isoform_ac": "A0AC58HCB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97/entry#A0AC58HCB7-1", "sequence": { "sequence": "MVPSNTLQSCTLAGTSTFAEVPQSGLNDSVVDVSGLCTGWIAQTTSTTALQPLSHWTPPDCQHHDPAIPSHADMYVQPICPGYTVVGSSPMLTFAHAPLFTNLATVSTSSSVLPQVEVPDSSLTYIPWAQPLSTIPGPVMQASSALSAPQLFPVPLTLPVLSPEPEPPQVEPQQAPEGTLALEKLLEDNEVHKESYICNSSLFAEDI", "length": 207, "header": "tr|A0AC58HCB7-1|A0AC58HCB7_DANRE Computationally mapped isoform of POU domain class 2-associating factor 1 isoform X4 OS=Danio rerio OX=7955 GN=pou2af1 PE=4 SV=1 CANONICAL=A0A8M9PC97-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103908823", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103908823", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TGP4-1", "protein_name": "POU class 2 homeobox associating factor 1", "gene_name": "POU2AF1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLWQKPAAPEQAPAPPRPYQGVRVKEPVKELLRRKRGHASSGAPVAPTAVVLPHQPLATYTTVGPSCLDMEVSASTVTEEGALCTGWLSQPAPAALQPLAPWTPYTEYVSHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASQPLITNVTTRSAATPTVGPQLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDVEDPRRTISSLLLEEEDSDTYSLNHTLSVEGF", "length": 251 }, "evidence": [ { "id": "A0A8M9PC97", "url": "https://omabrowser.org/oma/group/A0A8M9PC97/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q16633-1", "protein_name": "POU domain class 2-associating factor 1", "gene_name": "POU2AF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLWQKPTAPEQAPAPARPYQGVRVKEPVKELLRRKRGHASSGAAPAPTAVVLPHQPLATYTTVGPSCLDMEGSVSAVTEEAALCAGWLSQPTPATLQPLAPWTPYTEYVPHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASPPLITNVTTRSSATPAVGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLQDMEDPRRAASSLTIDKLLLEEEDSDAYALNHTLSVEGF", "length": 256 }, "evidence": [ { "id": "A0A8M9PC97", "url": "https://omabrowser.org/oma/group/A0A8M9PC97/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q2KJA4-1", "protein_name": "POU domain class 2-associating factor 1", "gene_name": "POU2AF1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLWQKPTAPEQAPAPPRPYQGVRVKEPVKELLRRKRGHASSGASVTPTAVVLPHQPLATYTTVGPSCLDMEVSASTVTEEGALCAGWLSQPAPAALQPLAPWTPYTEYVSHEAVSCPYSADMYVQPVCPSYTVVGPSSVLTYASQPLITNVTTRSAAAPTVGPPLEGPEHQAPLTYFPWPQPLSTLPTSTLQYQPPAPALPGPQFVQLPISIPEPVLPDAEDPRRAIGSLTIDKLLLEEEDSDTYALNHTLSVEGF", "length": 256 }, "evidence": [ { "id": "A0A8M9PC97", "url": "https://omabrowser.org/oma/group/A0A8M9PC97/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q64693-1", "protein_name": "POU domain class 2-associating factor 1", "gene_name": "Pou2af1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLWQKSTAPEQAPAPPRPYQGVRVKEPVKELLRRKRGHTSVGAAGPPTAVVLPHQPLATYSTVGPSCLDMEVSASTVTEEGTLCAGWLSQPAPATLQPLAPWTPYTEYVSHEAVSCPYSTDMYVQPVCPSYTVVGPSSVLTYASPPLITNVTPRSTATPAVGPQLEGPEHQAPLTYFPWPQPLSTLPTSSLQYQPPAPTLSGPQFVQLPISIPEPVLQDMDDPRRAISSLTIDKLLLEEEESNTYELNHTLSVEGF", "length": 256 }, "evidence": [ { "id": "A0A8M9PC97", "url": "https://omabrowser.org/oma/group/A0A8M9PC97/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97" } ], "pmid": "" }, { "name": "POU domain binding", "id": "GO:0070974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070974", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97" } ], "pmid": "" }, { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "RNA polymerase II transcription regulator complex", "id": "GO:0090575", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090575", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PC97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC97" }, { "id": "PS52003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS52003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "OCA", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 33, "start_aa": "Ser", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 240, "end_pos": 242 }, { "start_pos": 68, "end_pos": 70 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PH17-1", "uniprot_ac": "A0A8M9PH17", "uniprot_id": "A0A8M9PH17_DANRE", "mass": { "chemical_mass": 49155.0, "monoisotopic_mass": 49155.0 }, "refseq": { "ac": "XP_021326258", "name": "guanine nucleotide exchange factor for Rab-3A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326258" }, "gene_names": [ { "name": "rab3il1", "type": "recommended", "evidence": [ { "id": "A0A8M9PH17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH17" } ] }, { "name": "rab3il1", "type": "synonym", "evidence": [ { "id": "XP_021326258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326258" } ] } ], "protein_names": [ { "name": "Guanine nucleotide exchange factor for Rab-3A isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PH17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH17/entry#names_and_taxonomy" } ] }, { "name": "guanine nucleotide exchange factor for Rab-3A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021326258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326258" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021326258.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326258", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326258" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PH17", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH17" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rab3il1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH17", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110921-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110921-5", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100331248", "url": "https://www.ncbi.nlm.nih.gov/gene/100331248", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009449", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009449", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040351", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040351", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100331248", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331248", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PH17", "url": "https://www.orthodb.org/?gene=A0A8M9PH17", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14430", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14430", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14430:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14430:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25555", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25555", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021326258", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326258", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PH17", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PH17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32THP7", "url": "https://www.uniprot.org/uniprotkb/A0AB32THP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32THP7-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32THP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TJJ9", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TJJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IWT6", "url": "https://www.uniprot.org/uniprotkb/A0AC58IWT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IWT6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IWT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110921-5", "url": "https://zfin.org/ZDB-GENE-110921-5", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDAFEGLHQVQLSSSPPTAPGYEVLLTRHSGIAVYSSPVFFSRGEIAEHHHHHHHHHTAEEERCPVGRLVDLEPEPSPRLEGDDGGRREKKPPDEAGADRREAYNMSRLRSSSLEIKEKGTEFLREQLDAAQKELKLKDEECERLSHVRNQLEQELEELTASLFEEAHKMVREANVKQAAAEKQLKEAQGKIDVLQAEVSALKTLVLTSTPSSPNRQLHPQLLSPGSSRASSRPFGHTRNKSASGALQTEPTNPEKDTVHHDRELDSVLFAEFLSWKECPNLERSSAFISRVYREDIGPCLSFTSAELSQSVQRCVENNSLTIEPVITSSLPTDKNIHQGGTNGCWTPIETKCALSGLTRPCRHRIKLGDKENYYYISLSSRARITAVCNFFTYIRYIQQGLVRQDVQQMFWEVMRLRREMSVAKLGFFHTEHS", "length": 434, "header": "tr|A0A8M9PH17-1|A0A8M9PH17_DANRE Isoform 1 of Guanine nucleotide exchange factor for Rab-3A isoform X1 OS=Danio rerio OX=7955 GN=rab3il1 PE=3 SV=3 CANONICAL=A0A8M9PH17-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PH17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH17/entry#A0A8M9PH17-1", "sequence": { "sequence": "MDAFEGLHQVQLSSSPPTAPGYEVLLTRHSGIAVYSSPVFFSRGEIAEHHHHHHHHHTAEEERCPVGRLVDLEPEPSPRLEGDDGGRREKKPPDEAGADRREAYNMSRLRSSSLEIKEKGTEFLREQLDAAQKELKLKDEECERLSHVRNQLEQELEELTASLFEEAHKMVREANVKQAAAEKQLKEAQGKIDVLQAEVSALKTLVLTSTPSSPNRQLHPQLLSPGSSRASSRPFGHTRNKSASGALQTEPTNPEKDTVHHDRELDSVLFAEFLSWKECPNLERSSAFISRVYREDIGPCLSFTSAELSQSVQRCVENNSLTIEPVITSSLPTDKNIHQGGTNGCWTPIETKCALSGLTRPCRHRIKLGDKENYYYISLSSRARITAVCNFFTYIRYIQQGLVRQDVQQMFWEVMRLRREMSVAKLGFFHTEHS", "length": 434, "header": "tr|A0A8M9PH17-1|A0A8M9PH17_DANRE Isoform 1 of Guanine nucleotide exchange factor for Rab-3A isoform X1 OS=Danio rerio OX=7955 GN=rab3il1 PE=3 SV=3 CANONICAL=A0A8M9PH17-1" }, "locus": {} }, { "isoform_ac": "A0AB32THP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH17/entry#A0AB32THP7-1", "sequence": { "sequence": "MDAFEGLHQVQLSSSPPTAPGYEVLLTRHSGIAVYSSPVFFSRGEIAEHHHHHHHHHTAEEERCPVGRLVDLEPEPSPRLEGDDGGRREKKPPDEAGADRREAYNMSRLRSSSLEIKEKGTEFLREQLDAAQKELKLKDEECERLSHVRNQLEQELEELTASLFEEAHKMVREANVKQAAAEKQLKEAQGKIDVLQAEVSALKTLVLTSTPSSPNRQLHPQLLSPGSSRASSRPFGHTRNKSASGALQTEPTNPEKDTVHHDRELDSVLFAEFLSWKECPNLERSSAFISRVYREDIGPCLSFTSAELSQSVQRCVENNSLTIEPVITSSLPTDKNIHQGGTNKCALSGLTRPCRHRIKLGDKENYYYISLSSRARITAVCNFFTYIRYIQQGLVRQDVQQMFWEVMRLRREMSVAKLGFFHTEHS", "length": 426, "header": "tr|A0AB32THP7-1|A0A8M9PH17_DANRE Computationally mapped isoform of Guanine nucleotide exchange factor for Rab-3A isoform X1 OS=Danio rerio OX=7955 GN=rab3il1 PE=3 SV=2 CANONICAL=A0A8M9PH17-1" }, "locus": {} }, { "isoform_ac": "A0AB32TJJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH17/entry#A0AB32TJJ9-1", "sequence": { "sequence": "MSRLRSSSLEIKEKGTEFLREQLDAAQKELKLKDEECERLSHVRNQLEQELEELTASLFEEAHKMVREANVKQAAAEKQLKEAQGKIDVLQAEVSALKTLVLTSTPSSPNRQLHPQLLSPGSSRASSRPFGHTRNKSASGALQTEPTNPEKDTVHHDRELDSVLFAEFLSWKECPNLERSSAFISRVYREDIGPCLSFTSAELSQSVQRCVENNSLTIEPVITSSLPTDKNIHQGGTNGCWTPIETKCALSGLTRPCRHRIKLGDKENYYYISLSSRARITAVCNFFTYIRYIQQGLVRQDVQQMFWEVMRLRREMSVAKLGFFHTEHS", "length": 329, "header": "tr|A0AB32TJJ9-1|A0A8M9PH17_DANRE Computationally mapped isoform of Guanine nucleotide exchange factor for Rab-3A isoform X1 OS=Danio rerio OX=7955 GN=rab3il1 PE=3 SV=1 CANONICAL=A0A8M9PH17-1" }, "locus": {} }, { "isoform_ac": "A0AC58IWT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH17/entry#A0AC58IWT6-1", "sequence": { "sequence": "MSRLRSSSLEIKEKGTEFLREQLDAAQKELKLKDEECERLSHVRNQLEQELEELTASLFEEAHKMVREANVKQAAAEKQLKEAQGKIDVLQAEVSALKTLVLTSTPSSPNRQLHPQLLSPGSSRASSRPFGHTRNKSASGALQTEPTNPEKDTVHHDRELDSVLFAEFLSWKECPNLERSSAFISRVYREDIGPCLSFTSAELSQSVQRCVENNSLTIEPVITSSLPTDKNIHQGGTNKCALSGLTRPCRHRIKLGDKENYYYISLSSRARITAVCNFFTYIRYIQQGLVRQDVQQMFWEVMRLRREMSVAKLGFFHTEHS", "length": 321, "header": "tr|A0AC58IWT6-1|A0AC58IWT6_DANRE Computationally mapped isoform of Guanine nucleotide exchange factor for Rab-3A isoform X4 OS=Danio rerio OX=7955 GN=rab3il1 PE=3 SV=1 CANONICAL=A0A8M9PH17-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100331248", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331248", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AC58J6L5-1", "protein_name": "Rab-3A-interacting protein isoform X1", "gene_name": "rab3ip", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKIFWAMASEPLEGFHEVNLASPTTPDVHGVIDPSPPKHNAPPSTLYRTHSLSSSQNAASALRADQLPTQPVYSAPRHLGGDDTLNGSGNDPAAVDAVDADGEDGLGLSTDGLSRLRSPSVMEVREKGYEKLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVHEANLKQATAEKQLKEALGKIDVLQAEVAALKTLVLSTSPTSPCKEMPPGPKAPFKKGHVRNKSTSSAMLGSQQEVAVTQPIVRECKEVDSLLFTEFKAWKEEPTLERSCSFLERIYREDIYPCLTFSKSELGSAILEAVEQNTLSVEPVGFQPLPVVRASAVECGGPKMAETLVKCALCGQTKTCKHRIKFGDSSSYYYVSPFCRYRITSVCNFFTYIRYILQGLVKQQDAEQMFWEVLQLRKEMSNAKLGFYKDEL", "length": 437 }, "evidence": [ { "id": "SGD:S000005216", "url": "https://alliancegenome.org/gene/SGD:S000005216#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P17065-1", "protein_name": "Rab guanine nucleotide exchange factor SEC2", "gene_name": "SEC2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDASEEAKRVSIQVTSLSTQLIESVDKQSHLEEQLNKSLKTIASQKAAIENYNQLKEDYNTLKRELSDRDDEVKRLREDIAKENELRTKAEEEADKLNKEVEDLTASLFDEANNMVADARKEKYAIEILNKRLTEQLREKDTLLDTLTLQLKNLKKVMHSLDNESTVTNNSNRYSTILSDSATSSSTSLNKVPTSYSLASQDIYSGIVYSPSISSIRYDISLYNEFLKFVAALPRCENIKATSTESKLIRRLVNDEIQPILKIDNASGIGWLVKKTLLSLIIDGLVVVEPLSGVNATYQIGYNSSSPAKQATSNMPKMFKFPLDSPPVAVHAACSFCGESRDDIIEHARMYILKTLHKTDDGKEQVTNTYPLCHWCLLKLRQTCEIFAFLRSLKVGAWHLEKLTTQNITKEDLEKFSEVTKHTKRDGRVSSQDKKTKRLSFMAGLGINSSTKNKPKMEIFSSETNAKPGQPTTNIQRAWLQLCKLRCILHWTHIGIWAVDDSISSKIGPLVEDDSDEDQNDAISVRLQDKALWKQDAKRPFSSSSAEESQKSDAFDFESGDMENEITGESSSDESSSDGSSTDNSTADSSSEDESSLADSTTSSADSSSPESIDNGEGDDTVTKDDKSSIKSANNNEENSDCGDKKGRSIIKKKAPQRKIQKKKLLQDLDDLEEQFREESAIDQTEFENAESNVKQNISSKRASSGDENSKKDNNEKTLKTNLTIGDKTQEQIGENSPSSGLHASSSNDDNFDDAQEQQ", "length": 759 }, "evidence": [ { "id": "MGI:1922010", "url": "https://alliancegenome.org/gene/MGI:1922010#orthology", "database": "AGR" }, { "id": "HGNC:9780", "url": "https://alliancegenome.org/gene/HGNC:9780#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110921-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110921-5#orthology", "database": "AGR" }, { "id": "RGD:619764", "url": "https://alliancegenome.org/gene/RGD:619764#orthology", "database": "AGR" }, { "id": "SGD:S000005216", "url": "https://alliancegenome.org/gene/SGD:S000005216#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q62739-1", "protein_name": "Rab-3A-interacting protein", "gene_name": "Rab3ip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANDPLEGFHEVNLASPTSPDLLGVCDPGTQEQTTSPSVIYRPHPSTLCSATIQANALNLSDLPTQPVYSSPRHLNCAEISNISIHVPEPASSVASEVAAGLTRFTSRKDSCNAEREFLQGATVTEASAGNDDIFGLSTDSLSRLRSPSVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVREANVKQATAEKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLAAGKTPFKRGHTRNKSTSSAMSGSHQDFSAIQPIVKDCREADLSLYNEFRSWKDEPTMDRTCPFLDKIYQEDIFPCLTFAKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPKKCALTGQSKPCKHRIKLGDSSSYYYISPVCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL", "length": 460 }, "evidence": [ { "id": "SGD:S000005216", "url": "https://alliancegenome.org/gene/SGD:S000005216#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68EF0-1", "protein_name": "Rab-3A-interacting protein", "gene_name": "Rab3ip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANDPLEGFHEVNLASPTSPDLLGVCDPGTQEQTTSPSVIYRPHPSTLCAAPLQANALDLSDLPTQPVYSSPRHFNCAEVSNISAHAPDPASSVPSAVASGLTKLTSRKDSCNAEREFLQGATITEASAGNDDIFGLSTDSLSRLRSPSVLEVREKGYERLKEELAKAQREAHKMVREANVKQATAEKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLAAAKTPFKRGHTRNKSTSSAMGGSHQDLSVIQPIVKDCKEADLSLYNEFRSWKDEPTMDRTCPFLDKIYQEDIFPCLTFAKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPKKCALTGQSKPCRHRIRLGDSSCCYYISPFCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL", "length": 428 }, "evidence": [ { "id": "SGD:S000005216", "url": "https://alliancegenome.org/gene/SGD:S000005216#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TBN0-1", "protein_name": "Guanine nucleotide exchange factor for Rab-3A", "gene_name": "RAB3IL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWSGPPQPDQGLPPPLAAVPVPWKSTDPCQGHRESPGALVETSAGEEAQGQEGPAAAQLDVLRLRSSSMEIREKGSEFLKEELHRAQKELKLKDEECERLSKVREQLEQELEELTASLFEEAHKMVREANMKQAASEKQLKEARGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSPTKAGPRKGHSRHKSTSSTLCPAVCPAAGHTLTPDREGKEVDTILFAEFQAWRESPTLDKTCPFLERVYREDVGPCLDFTMQELSVLVRAAVEDNTLTIEPVASQTLPTVKVAEVDCSSTNTCALSGLTRTCRHRIRLGDSKSHYYISPSSRARITAVCNFFTYIRYIQQGLVRQDAEPMFWEIMRLRKEMSLAKLGFFPQEA", "length": 382 }, "evidence": [ { "id": "MGI:1922010", "url": "https://alliancegenome.org/gene/MGI:1922010#orthology", "database": "AGR" }, { "id": "HGNC:9780", "url": "https://alliancegenome.org/gene/HGNC:9780#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110921-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110921-5#orthology", "database": "AGR" }, { "id": "RGD:619764", "url": "https://alliancegenome.org/gene/RGD:619764#orthology", "database": "AGR" }, { "id": "SGD:S000005216", "url": "https://alliancegenome.org/gene/SGD:S000005216#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VDV3-1", "protein_name": "Guanine nucleotide exchange factor for Rab-3A", "gene_name": "Rab3il1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWSGQPQQDEGLPVGLSAIPVPWKNLGPSKSNRESSGGLVEASTSWEEAQGEEHPAPAPLDVSRLRSSSMEIREKGSEFLKEELYKAQKELKLKDEECERLCKVRAQLEQELEELTASLFEEAHKMVREANMKQATSEKQLKEAWGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSPTKAGPRKGHSRQKSTSSSLCPVVCPTAGHIPTPDKEGKEVDTTLFAEFQAWRASPTLDKSCPFLERVYREDVGPCLDFTVQELSALVRTAVEDNTLTIEPVASQTLPAVKVPTVECNNTNTCALSGLARTCHHRIRLGDSDSHYYISPSSRARITAVCNFFTYIRYIQQGLVRQDAEPMFWEIMRLRKGMSLAKLGFFPQEA", "length": 383 }, "evidence": [ { "id": "MGI:1922010", "url": "https://alliancegenome.org/gene/MGI:1922010#orthology", "database": "AGR" }, { "id": "HGNC:9780", "url": "https://alliancegenome.org/gene/HGNC:9780#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110921-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110921-5#orthology", "database": "AGR" }, { "id": "RGD:619764", "url": "https://alliancegenome.org/gene/RGD:619764#orthology", "database": "AGR" }, { "id": "SGD:S000005216", "url": "https://alliancegenome.org/gene/SGD:S000005216#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96QF0-1", "protein_name": "Rab-3A-interacting protein", "gene_name": "RAB3IP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLKKMKGLSYDEAFAMANDPLEGFHEVNLASPTSPDLLGVYESGTQEQTTSPSVIYRPHPSALSSVPIQANALDVSELPTQPVYSSPRRLNCAEISSISFHVTDPAPCSTSGVTAGLTKLTTRKDNYNAEREFLQGATITEACDGSDDIFGLSTDSLSRLRSPSVLEVREKGYERLKEELAKAQRELKLKDEECERLSKVRDQLGQELEELTASLFEEAHKMVREANIKQATAEKQLKEAQGKIDVLQAEVAALKTLVLSSSPTSPTQEPLPGGKTPFKKGHTRNKSTSSAMSGSHQDLSVIQPIVKDCKEADLSLYNEFRLWKDEPTMDRTCPFLDKIYQEDIFPCLTFSKSELASAVLEAVENNTLSIEPVGLQPIRFVKASAVECGGPKKCALTGQSKSCKHRIKLGDSSNYYYISPFCRYRITSVCNFFTYIRYIQQGLVKQQDVDQMFWEVMQLRKEMSLAKLGYFKEEL", "length": 476 }, "evidence": [ { "id": "SGD:S000005216", "url": "https://alliancegenome.org/gene/SGD:S000005216#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99NH3-1", "protein_name": "Guanine nucleotide exchange factor for Rab-3A", "gene_name": "Rab3il1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSGPPQQDEGLPVGLSAISVPWKNLGPSKGNRKSPGGLVEASASWEEAGGEEHPAAAPLDVSRLRSSSMEIREKGSEFLKEELYKAQKELKLKDEECERLCKVRAQLEQELEELTASLFEEAHKMVREANMKQAASEKQLKEAWGKIDMLQAEVTALKTLVITSTPASPNRELHPQLLSPTKAGPRKGHSRQKSTSSLCPVVCPTAGHIPTPDKEGKEVDTTLFAEFQAWRASPTLDKNCPFLERVYREDVGPCLDFTVQELSALVRTAVEDNTLTIEPVASQTLPNVECNNTNTCALSGLARTCHHRIRLGDSDGHYYISPSSRARITAVCNFFTYVRYIQQGLVRQDAEPMFWEIMRLRKGMSLAKLGFFPQEA", "length": 377 }, "evidence": [ { "id": "MGI:1922010", "url": "https://alliancegenome.org/gene/MGI:1922010#orthology", "database": "AGR" }, { "id": "HGNC:9780", "url": "https://alliancegenome.org/gene/HGNC:9780#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110921-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110921-5#orthology", "database": "AGR" }, { "id": "RGD:619764", "url": "https://alliancegenome.org/gene/RGD:619764#orthology", "database": "AGR" }, { "id": "SGD:S000005216", "url": "https://alliancegenome.org/gene/SGD:S000005216#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PH17", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH17" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PH17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH17" }, { "id": "PF06428", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06428" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GDP/GTP exchange factor Sec2 N-terminal", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 205, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 240, "end_pos": 242 }, { "start_pos": 318, "end_pos": 320 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PF96-1", "uniprot_ac": "A0A8M9PF96", "uniprot_id": "A0A8M9PF96_DANRE", "mass": { "chemical_mass": 38322.0, "monoisotopic_mass": 38322.0 }, "refseq": { "ac": "XP_021325568", "name": "protein phosphatase 1 regulatory subunit 12B isoform X8", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325568" }, "gene_names": [ { "name": "ppp1r12b", "type": "recommended", "evidence": [ { "id": "A0A8M9PF96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96" } ] }, { "name": "ppp1r12b", "type": "synonym", "evidence": [ { "id": "XP_021325568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325568" } ] } ], "protein_names": [ { "name": "Protein phosphatase 1 regulatory subunit 12B isoform X8", "type": "synonym", "evidence": [ { "id": "A0A8M9PF96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#names_and_taxonomy" } ] }, { "name": "protein phosphatase 1 regulatory subunit 12B isoform X8", "type": "synonym", "evidence": [ { "id": "XP_021325568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325568" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325568.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325568" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF96", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ppp1r12b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120920-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120920-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PF96", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PF96", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd21930", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21930", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101885790", "url": "https://www.ncbi.nlm.nih.gov/gene/101885790", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051226", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051226", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885790", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885790", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PF96", "url": "https://www.orthodb.org/?gene=A0A8M9PF96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24179:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24179:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24179:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24179:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15898", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15898", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325568", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325568", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PF96", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PF96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PKZ0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PKZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PTC3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PTC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PWQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PWQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PWQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PWQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32THS1", "url": "https://www.uniprot.org/uniprotkb/A0AB32THS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32THS1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32THS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TJ74", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJ74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TJ74-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJ74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INR4", "url": "https://www.uniprot.org/uniprotkb/A0AC58INR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INR4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INR6", "url": "https://www.uniprot.org/uniprotkb/A0AC58INR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INR6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INR8", "url": "https://www.uniprot.org/uniprotkb/A0AC58INR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INR8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INS3", "url": "https://www.uniprot.org/uniprotkb/A0AC58INS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INS3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INS4", "url": "https://www.uniprot.org/uniprotkb/A0AC58INS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INS4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INT5", "url": "https://www.uniprot.org/uniprotkb/A0AC58INT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INT5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INT6", "url": "https://www.uniprot.org/uniprotkb/A0AC58INT6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INT6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INT6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INU1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INU1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INU2", "url": "https://www.uniprot.org/uniprotkb/A0AC58INU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INU2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INV9", "url": "https://www.uniprot.org/uniprotkb/A0AC58INV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INV9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120920-4", "url": "https://zfin.org/ZDB-GENE-120920-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MQDCLIRTHMIPVRDEDAESQRKAKSRQARQTRRATQGVTLSELMEAKKTFSTSKLEMQPGEVCRSTERLCVQRVHEDTTDSSPSLKTLEQHSEDHLDEQGNWKRRSGPNPERSSFCMSSVKGACGFTPSLKNHSSLKESEWMDENDNILYGCSGASLAQKLIEDSDLPGLLTEQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQKQDRISERSTVFESEKREKEALEKRVSDMEEELKTPPALARLQALRRGNARLLVENKAMLRTLARLSQTACLPESEDL", "length": 337, "header": "tr|A0A8M9PF96-1|A0A8M9PF96_DANRE Isoform 1 of Protein phosphatase 1 regulatory subunit 12B isoform X8 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=2 CANONICAL=A0A8M9PF96-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PF96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0A8M9PF96-1", "sequence": { "sequence": "MQDCLIRTHMIPVRDEDAESQRKAKSRQARQTRRATQGVTLSELMEAKKTFSTSKLEMQPGEVCRSTERLCVQRVHEDTTDSSPSLKTLEQHSEDHLDEQGNWKRRSGPNPERSSFCMSSVKGACGFTPSLKNHSSLKESEWMDENDNILYGCSGASLAQKLIEDSDLPGLLTEQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQKQDRISERSTVFESEKREKEALEKRVSDMEEELKTPPALARLQALRRGNARLLVENKAMLRTLARLSQTACLPESEDL", "length": 337, "header": "tr|A0A8M9PF96-1|A0A8M9PF96_DANRE Isoform 1 of Protein phosphatase 1 regulatory subunit 12B isoform X8 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=2 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PKZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0A8M9PKZ0-1", "sequence": { "sequence": "MQDCLIRTHMIPVRDEDAESQRKAKSRQARQTRRATQGVTLSELMEAKKTFSTSKLEMQPGEVCRSTERLCVQRVHEDTTDSSPSLKTLEQHSEDHLDEQGNWKRRSGPNPERSSFCMSSVKGACGFTPSLKNHSSLKESEWMDENDNILYGCSGASLAQKLIEDSDLPGLLTEQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQKQDRISERSTVFESEKREKEALEKRVSDMEEELKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 321, "header": "tr|A0A8M9PKZ0-1|A0A8M9PKZ0_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X1 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=2 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PTC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0A8M9PTC3-1", "sequence": { "sequence": "MQDCLIRTHMIPVRDEDAESQRKAKSRQARQTRRATQGVTLSELMEAKKTFSTSKLEMQPGEVCRSTERLCVQRVHEDTTDSSPSLKTLEQHSEDHLDEQGNWKRRSGPNPERSSFCMSSVKGACGFTPSLKNHSSLKESEWMDENDNILYGCSGASLAQKLIEDSDLPGLLTEQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQEKEALEKRVSDMEEELKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 304, "header": "tr|A0A8M9PTC3-1|A0A8M9PF96_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X8 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=2 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PWQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0A8M9PWQ3-1", "sequence": { "sequence": "MQDCLIRTHMIPVRDEDAESQRKAKSRQARQTRRATQGVTLSELMEAKKTFSTSKLEMQPGEVCRSTERLCVQRVHEDTTDSSPSLKTLEQHSEDHLDEQGNWKRRSGPNPERSSFCMSSVKGACGFTPSLKNHSSLKESEWMDENDNILYGCSGASLAQKLIEDSDLPGLLTEQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQEKEALEKRVSDMEEELKTPPALARLQALRRGNARLLVENKAMLRTLARLSQTACLPESEDL", "length": 320, "header": "tr|A0A8M9PWQ3-1|A0A8M9PF96_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X8 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=2 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0AB32THS1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0AB32THS1-1", "sequence": { "sequence": "MQDCLIRTHMIPVRDEDAESQRKAKSRQARQTRRATQGVTLSELMEAKKTFSTSKLEMQPGEVCRSTERLCVQRVHEDTTDSSPSLKTLEQHSEDHLDEQGNWKRRSGPNPERSSFCMSSVKGACGFTPSLKNHSSLKESEWMDENDNILYGCSGASLAQKLIEDSDLPGLLTEQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQKQDRISERSTVFESEKREKEALEKRVSDMEEELKQTPSVRFRYQF", "length": 304, "header": "tr|A0AB32THS1-1|A0A8M9PF96_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X8 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=2 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0AB32TJ74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0AB32TJ74-1", "sequence": { "sequence": "MQDCLIRTHMIPVRDEDAESQRKAKSRQARQTRRATQGVTLSELMEAKKTFSTSKLEMQPGEVCRSTERLCVQRVHEDTTDSSPSLKTLEQHSEDHLDEQGNWKRRSGPNPERSSFCMSSVKGACGFTPSLKNHSSLKESEWMDENDNILYGCSGASLAQKLIEDSDLPGLLTEQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQKQDRISERSTVFESEKREKEALEKRVSDMEEELKTPSVRFRYQF", "length": 303, "header": "tr|A0AB32TJ74-1|A0A8M9PF96_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X8 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=2 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0AC58INR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0AC58INR4-1", "sequence": { "sequence": "MSSVKGACGFTPSLKNHSSLKESEWMDENDNILYGCSGASLAQKLIEDSDLPGLLTEQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQKQDRISERSTVFESEKREKEALEKRVSDMEEELKTPSVRFRYQF", "length": 186, "header": "tr|A0AC58INR4-1|A0AC58INR4_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X9 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=1 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0AC58INR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0AC58INR6-1", "sequence": { "sequence": "MSSLYSRSKDLSSRSRKSLSDSPPSSPSPSTKTFRQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQKQDRISERSTVFESEKREKEALEKRVSDMEEELKTPPALARLQALRRGNARLLVENKAMLRTLARLSQTACLPESEDL", "length": 198, "header": "tr|A0AC58INR6-1|A0AC58INR6_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X7 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=1 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0AC58INR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0AC58INR8-1", "sequence": { "sequence": "MSSLYSRSKDLSSRSRKSLSDSPPSSPSPSTKTFRQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQEKEALEKRVSDMEEELKTPPALARLQALRRGNARLLVENKAMLRTLARLSQTACLPESEDL", "length": 181, "header": "tr|A0AC58INR8-1|A0AC58INR8_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X11 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=1 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0AC58INS3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0AC58INS3-1", "sequence": { "sequence": "MSSVKGACGFTPSLKNHSSLKESEWMDENDNILYGCSGASLAQKLIEDSDLPGLLTEQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQEKEALEKRVSDMEEELKVHFYQMLYF", "length": 168, "header": "tr|A0AC58INS3-1|A0AC58INS3_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X12 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=1 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0AC58INS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0AC58INS4-1", "sequence": { "sequence": "MSSLYSRSKDLSSRSRKSLSDSPPSSPSPSTKTFRQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQKQDRISERSTVFESEKREKEALEKRVSDMEEELKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 182, "header": "tr|A0AC58INS4-1|A0AC58INS4_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X10 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=1 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0AC58INT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0AC58INT5-1", "sequence": { "sequence": "MSSLYSRSKDLSSRSRKSLSDSPPSSPSPSTKTFRQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQKQDRISERSTVFESEKREKEALEKRVSDMEEELKQTPSVRFRYQF", "length": 165, "header": "tr|A0AC58INT5-1|A0AC58INT5_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X13 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=1 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0AC58INT6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0AC58INT6-1", "sequence": { "sequence": "MSSLYSRSKDLSSRSRKSLSDSPPSSPSPSTKTFRQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQEKEALEKRVSDMEEELKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 165, "header": "tr|A0AC58INT6-1|A0AC58INT6_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X14 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=1 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0AC58INU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0AC58INU1-1", "sequence": { "sequence": "MSSLYSRSKDLSSRSRKSLSDSPPSSPSPSTKTFRQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQKQDRISERSTVFESEKREKEALEKRVSDMEEELKTPSVRFRYQF", "length": 164, "header": "tr|A0AC58INU1-1|A0AC58INU1_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X15 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=1 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0AC58INU2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0AC58INU2-1", "sequence": { "sequence": "MSSVKGACGFTPSLKNHSSLKESEWMDENDNILYGCSGASLAQKLIEDSDLPGLLTEQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQKQDRISERSTVFESEKREKEALEKRVSDMEEELKVLTELKSDNQRLKDENGALIRVISKLSK", "length": 204, "header": "tr|A0AC58INU2-1|A0AC58INU2_DANRE Computationally mapped isoform of Protein phosphatase 1 regulatory subunit 12B isoform X6 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=1 CANONICAL=A0A8M9PF96-1" }, "locus": {} }, { "isoform_ac": "A0AC58INV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96/entry#A0AC58INV9-1", "sequence": { "sequence": "MSSLYSRSKDLSSRSRKSLSDSPPSSPSPSTKTFRQDRASRSDSSGVDSLSDRLSSRTSTYTRRENRLASLSKPDEDSTSKDYKKLYEDALSENEKLKSRLEDSKQELTKIRSQLDRVTQEKEALEKRVSDMEEELKTPSVRFRYQF", "length": 147, "header": "tr|A0AC58INV9-1|A0AC58INV9_DANRE Computationally mapped isoform of Uncharacterized protein ppp1r12b isoform X16 OS=Danio rerio OX=7955 GN=ppp1r12b PE=4 SV=1 CANONICAL=A0A8M9PF96-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885790", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885790", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF96", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PF96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF96" }, { "id": "PF15898", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15898" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "cGMP-dependent protein kinase interacting", "eco_id": "ECO_0000259", "start_pos": 221, "end_pos": 327, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 133, "end_pos": 135 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PGY2-1", "uniprot_ac": "A0A8M9PGY2", "uniprot_id": "A0A8M9PGY2_DANRE", "mass": { "chemical_mass": 48197.0, "monoisotopic_mass": 48197.0 }, "refseq": { "ac": "NP_001427700", "name": "zinc finger protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427700" }, "gene_names": [ { "name": "zgc:174653", "type": "recommended", "evidence": [ { "id": "A0A8M9PGY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" } ] }, { "name": "zgc:174653", "type": "synonym", "evidence": [ { "id": "NP_001427700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427700" }, { "id": "A0A8M9PGY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" } ] }, { "name": "znf1069", "type": "synonym", "evidence": [ { "id": "A0A8M9PGY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" } ] } ], "protein_names": [ { "name": "Zinc finger protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PGY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein", "type": "synonym", "evidence": [ { "id": "NP_001427700", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427700" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR26395014.1046861.1, SRR32588716.21845758.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476752, SAMEA4476755 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On May 29, 2025 this sequence version replaced XP_021330572.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001427700", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427700" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0AB32TIA9", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIA9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080218-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080218-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PGY2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PGY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00229", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00229", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100141328", "url": "https://www.ncbi.nlm.nih.gov/gene/100141328", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23226:SF240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF114", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF114", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001427700", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427700", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PGY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TIA9", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TIA9-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TMN8", "url": "https://www.uniprot.org/uniprotkb/A0AB32TMN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TMN8-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TMN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TQ38", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQ38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TQ38-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQ38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4T1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4T1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4T1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4U6", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4U6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4U6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4U6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080218-2", "url": "https://zfin.org/ZDB-GENE-080218-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDLQEQTDLMMLKEETHQQNEVEEKHQDIPTDEKPTLTKKTSSHRRHLNYKSECNFSCKQSRKSFSQKPNLDVYTRVHNREKHYTCKQCGKSFPKIHFLKAHMRIHIGERSYTCQQCGKIFHYARNLAAHMRIHTGEKPYSCPQCGKSFKQNNNLEVHMRTHTGERSFTCTQCGKSFAKKQNLKIHMRIHTGEKPFTCTECGKSFRCKSTFNIHKRTHTGEKPYRCTECGKSFPNKSTFNNHMRIHTGEKPYRCTECGKSFIRKSTLNYHVRTHTGEKLFACVQCGKSFTTKLSLMNHMNGHTGTIVFTCDQCGKSLTRKDSIKRHMKTHSGERFRCSECGKDFKHERSLRAHMKLHNAEQSPQHLGLVHTNTGIFKTAAFSCSLAVHSSEVYL", "length": 415, "header": "tr|A0A8M9PGY2-1|A0A8M9PGY2_DANRE Isoform 1 of Zinc finger protein isoform X1 OS=Danio rerio OX=7955 GN= PE=3 SV=2 CANONICAL=A0A8M9PGY2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PGY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2/entry#A0A8M9PGY2-1", "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDLQEQTDLMMLKEETHQQNEVEEKHQDIPTDEKPTLTKKTSSHRRHLNYKSECNFSCKQSRKSFSQKPNLDVYTRVHNREKHYTCKQCGKSFPKIHFLKAHMRIHIGERSYTCQQCGKIFHYARNLAAHMRIHTGEKPYSCPQCGKSFKQNNNLEVHMRTHTGERSFTCTQCGKSFAKKQNLKIHMRIHTGEKPFTCTECGKSFRCKSTFNIHKRTHTGEKPYRCTECGKSFPNKSTFNNHMRIHTGEKPYRCTECGKSFIRKSTLNYHVRTHTGEKLFACVQCGKSFTTKLSLMNHMNGHTGTIVFTCDQCGKSLTRKDSIKRHMKTHSGERFRCSECGKDFKHERSLRAHMKLHNAEQSPQHLGLVHTNTGIFKTAAFSCSLAVHSSEVYL", "length": 415, "header": "tr|A0A8M9PGY2-1|A0A8M9PGY2_DANRE Isoform 1 of Zinc finger protein isoform X1 OS=Danio rerio OX=7955 GN= PE=3 SV=2 CANONICAL=A0A8M9PGY2-1" }, "locus": {} }, { "isoform_ac": "A0AB32TIA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2/entry#A0AB32TIA9-1", "sequence": { "sequence": "MMLKEETHQQNEVEEKHQDIPTDEKPTLTKKTSSHRRHLNYKSECNFSCKQSRKSFSQKPNLDVYTRVHNREKHYTCKQCGKSFPKIHFLKAHMRIHIGERSYTCQQCGKIFHYARNLAAHMRIHTGEKPYSCPQCGKSFKQNNNLEVHMRTHTGERSFTCTQCGKSFAKKQNLKIHMRIHTGEKPFTCTECGKSFRCKSTFNIHKRTHTGEKPYRCTECGKSFPNKSTFNNHMRIHTGEKPYRCTECGKSFIRKSTLNYHVRTHTGEKLFACVQCGKSFTTKLSLMNHMNGHTGTIVFTCDQCGKSLTRKDSIKRHMKTHSGERFRCSECGKDFKHERSLRAHMKLHNAEQSPQHLGLVHTNTGIFKTAAFSCSLAVHSSEVYL", "length": 385, "header": "tr|A0AB32TIA9-1|A0A8M9PGY2_DANRE Computationally mapped isoform of Zinc finger protein isoform X1 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=A0A8M9PGY2-1" }, "locus": {} }, { "isoform_ac": "A0AB32TMN8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2/entry#A0AB32TMN8-1", "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDPQEQTNLIEENERKEEEHHVKIGEKTHLQTDGILKRRDKNCFTCTQCGKILASKSKLKIHMISHTGEKPFTCTQCGKSFSQSSHLNDHMMIHTGEKPFTCTQCGRSFNRSSHLNHHMRIHTGEKPFTCTQCGKSFNRSSHLNQHIRIHTGEKPITCTQCGKSFRQSSSIYKHMRIHTGEKPFTCTQCGKSFSQSSNFNLHMRIHTGEKPFTCTQCGKSFRQASSLNKHMRTHDLLWRDCTSVFTRGLIS", "length": 272, "header": "tr|A0AB32TMN8-1|A0A8M9PGY2_DANRE Computationally mapped isoform of Zinc finger protein isoform X1 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=A0A8M9PGY2-1" }, "locus": {} }, { "isoform_ac": "A0AB32TQ38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2/entry#A0AB32TQ38-1", "sequence": { "sequence": "MIKTFLKYGTRLVRPALKRLEDLIEENERKEEEHHVKIGEKTHLQTDGILKRRDKNCFTCTQCGKILASKSKLKIHMISHTGEKPFTCTQCGKSFSQSSHLNDHMMIHTGEKPFTCTQCGRSFNRSSHLNHHMRIHTGEKPFTCTQCGKSFNRSSHLNQHIRIHTGEKPITCTQCGKSFRQSSSIYKHMRIHTGEKPFTCTQCGKSFSQSSNFNLHMRIHTGEKPFTCTQCGKSFRQASSLNKHMRTHDLLWRDCTSVFTRGLIS", "length": 265, "header": "tr|A0AB32TQ38-1|A0A8M9PGY2_DANRE Computationally mapped isoform of Zinc finger protein isoform X1 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=A0A8M9PGY2-1" }, "locus": {} }, { "isoform_ac": "A0AC58J4T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2/entry#A0AC58J4T1-1", "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDLQEQTGEASMEALELELEEVESQIRALVVRRSRLRERLLAVPNAKAVSSPKVRGNYNHIIPSTSTPRPSLSRPSAPGARLSQASFTPTPGYHGAWVQPRKVLPRSRGRTSPPVFEISTENRFSPLRESGPDVAIIGDSIVRHVRAASSKGNKVRTFCFPGARVKNISTQIPTILGAAESPGAVVLHVGTNDTGLRQSEILKKDFRSLIETVRRTSPATQIIVSGPLPTYRRGNERLFRPDGLHPSRAGAELLSDNISRLLRTI", "length": 286, "header": "tr|A0AC58J4T1-1|A0AC58J4T1_DANRE Computationally mapped isoform of Zinc finger protein isoform X3 OS=Danio rerio OX=7955 GN=zgc:174653 PE=4 SV=1 CANONICAL=A0A8M9PGY2-1" }, "locus": {} }, { "isoform_ac": "A0AC58J4U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2/entry#A0AC58J4U6-1", "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDLQEQTGEASMEALELELEEVESQIRALVVRRSRLRERLLAVPNAKAVSSPKVRGNYNHIIPSTSTPRPSLSRPSAPGARLSQASFTPTPGYHGAWVQPRKVLPRSRGRTSPPVFEISTENRFSPLRESGPDVAIIGDSIVRHVRAASSKDSNHPGRCREPWCRCPPRGDKRHRAPAVGDPEEGLQEPDRDGSTHLARHADHRFWAASYLPPRK", "length": 236, "header": "tr|A0AC58J4U6-1|A0AC58J4U6_DANRE Computationally mapped isoform of Zinc finger protein isoform X7 OS=Danio rerio OX=7955 GN=zgc:174653 PE=4 SV=1 CANONICAL=A0A8M9PGY2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AH96-1", "protein_name": "Zinc finger protein 707-like 1", "gene_name": "Zfp707l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGCCYGGQHKCHLGWTNFYPPAHQRRCLCYLLDALMKPVIQVPVTFREVAVYFCREEWECLSFSQRTLYRDVMLENFRNLNELGCCGRKPSLISRLEQWDEPWVDKWDSSELERQKSVCPGGRKASAPEKTHSRTGAKSRTTLRKNVLTSGKAHFTRATSGRKLDNKSEALQNQTCGKSRRRQPGLKEQGKSAAEGHPFICGICGKALSCHSRLAAHQTVHTGTRSFECFECGQTFRWVSNLLRHQRNHTSEKPFCCEVCGQAFSLKDRLAQHQKIHTEHRPYVCSDCGKAFKQKSNLLRHKLVHTGERPFYCDNCGKTFRTKENLNHHQRIHSGEKPYTCGECGKAFRWPKGFSIHQRLHLTKKFYECEECGKGFRHLGFFTRHQRTHGRGEV", "length": 395 }, "evidence": [ { "id": "HGNC:27815", "url": "https://alliancegenome.org/gene/HGNC:27815#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3B221-1", "protein_name": "Uncharacterized protein si:cabz01032474.1", "gene_name": "si:cabz01032474.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFIKEESEDIRIVEVFTLKHEDPEEETGLMELKEETQELNEMEEVDSQHDLRTDEESTEGVQETESNFKCCHCGKCFSNEQNLEIHMRNQNGEKPFICKKCGMGFSQNRKLHVHMRIHTGEKRFPCPQCGKCFTVKYSLRVHMRVHTGENPYTCPECGKGFKQKNSFNYHMRTHKGLKIVETDSVEVDI", "length": 190 }, "evidence": [ { "id": "HGNC:27815", "url": "https://alliancegenome.org/gene/HGNC:27815#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YYQ9-1", "protein_name": "Uncharacterized protein si:dkey-30f3.2 isoform X1", "gene_name": "si:dkey-30f3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSFIKEESEDVKIEETFTVKQEDPQEQTDLMVLKEETQHWNKMEEQHQEITADEKPTLTEKTSSLGRSRKSKTECNFSSKQCRKSFSQKLNLDVHMRVHIREKPYTCEQCGKSFGQKKSFKTHMRIHTGERPYTCQQCGKSFCQAGNFAVHKRIHTGERPYTCQQCGKSFTQSGNLKDHIRTHNGGKKFTCTQCGKSFAQKQKYDTHMTIHTGEKPYRCTECGKSFTCKSALNNHMISHTGEKPFACVQCGKSFTTKTSLKNHMDGHTGIIVFICDQCGKSLTRKDYIKQHMKNHSREDRFRCSECGISFKQKINLSAHMKLHYAEQSPQH", "length": 331 }, "evidence": [ { "id": "MGI:3702408", "url": "https://alliancegenome.org/gene/MGI:3702408#orthology", "database": "AGR" }, { "id": "MGI:3652185", "url": "https://alliancegenome.org/gene/MGI:3652185#orthology", "database": "AGR" }, { "id": "MGI:3649811", "url": "https://alliancegenome.org/gene/MGI:3649811#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z2H8-1", "protein_name": "Uncharacterized protein znf982 isoform X1", "gene_name": "znf982", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSALTRSFSVESTELSSVPSSVKDEDSLLKNSEKMSDPEPCLIKQEDTEEEIALPPPVKDEDGLLKDSEKMSDPELYQIKQEETEEQIDLIVEEREVLSEDEEKHRVKGEIESHTKTEHNFLLKRPAIKAFTCTRCAKSFSYKCDLNHHIRIHNGEKPYKCSHCDKRFNRSGHLKTHERIHTGEKPYTCDQCGKSFVQISHLNQHMIIHNGEKTYTCDQCSKTFLIYSELKDHLKVHKNETKSHTCPDCGKNFIWHSSLKKHQKIHTGVREYMCSECEKTFITSGDLKQHQKIHTGEKPYMCSHCNKRFSHVKPLKVHERIHTGEKPYTCTQCGKSFRQSAHLNEHMLIHNGEKTHKCDHCGKTFLRPSELKKHLRVHTKEKPYSCSVCEKSFTQQSHLSQHQKIHTGVREYMCFACDKTYITAGDLKKHQRIHTGEKPFVCSDCNKSFRHSGHLTAHERIHTGEKPYACTQCEKTFRRPSNLNEHMMIHTGERPHKCEQCFQTFLRLAELKKHLRVHAKEKPQEVLHIDDIYLTENFTPYSQTSDFTVQYVD", "length": 554 }, "evidence": [ { "id": "HGNC:27815", "url": "https://alliancegenome.org/gene/HGNC:27815#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A7D2-1", "protein_name": "Uncharacterized protein LOC101882695", "gene_name": "wu:fb73h04", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFIKEESEDIKIEETFTVKHEETEEAFRVKHEDPEEQTELMPLKDESQEQNETEETVQDEGCLDLRSGEASEQTETSQKTAESNTCHHCGKSFTRKQYLTNHMRIHNGERPFKCHQCVKIFTQKQNFLDHMRIHTGEKPYTCQQCGKSFTWKRYLITHTRMHTGEKPYTCQECGKCFARKHMLTIHMRVHTGERPYPCQECGKGFTQKHILIDHMRIHTGERPHVCQQCGMSFTWKQYYTEHMRTHTGERPHACLQCGKNFTCKQNLTDHMRIHTGEKPFTCQQCGKCFTCKPNLRSHMKVHTGERPHACSQCGKSYPWKKNLKEHMRVHTGDQLSDANTSLIPM", "length": 346 }, "evidence": [ { "id": "MGI:3702408", "url": "https://alliancegenome.org/gene/MGI:3702408#orthology", "database": "AGR" }, { "id": "MGI:3652185", "url": "https://alliancegenome.org/gene/MGI:3652185#orthology", "database": "AGR" }, { "id": "MGI:3649811", "url": "https://alliancegenome.org/gene/MGI:3649811#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TEE3-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "zgc:194186", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFIKEESEDLKIEDTFTVKHEDAEQITDLMELKEETEVLDEEEEDQYEKRLDFKTEVLRCSDTEKTSSRKGAQISESGNPLSCQKCGKSFRRPSLLKVHMRIHTGERPYSCQECGKSFSHNANLGRHLRIHNREKPFTCQQCGKSFNRKGNLSSHMTVHSGEKLFTCQPCGISFTHKLSFKTHITVHNSEKPFTCEQCGKSFDQQESLKAHMRVHTAEKPFTCSHCGKSFSQRRYLADHMRIHTGEEPYTCSYCGRGFSYRHHISDHMRIHTGEKPFTCGHCGKSFSRKGVLNRHMMLHTGEKPYTCGHCGKSFKYRPALKQHMKVHI", "length": 329 }, "evidence": [ { "id": "MGI:3702408", "url": "https://alliancegenome.org/gene/MGI:3702408#orthology", "database": "AGR" }, { "id": "MGI:3652185", "url": "https://alliancegenome.org/gene/MGI:3652185#orthology", "database": "AGR" }, { "id": "MGI:3649811", "url": "https://alliancegenome.org/gene/MGI:3649811#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2ARR6-1", "protein_name": "Predicted gene 14418", "gene_name": "Gm14418", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLVTYDDVHVNFTQEEWALLHPSQKSLYKGVMLETYRNLTAIGYIWEEHTIEDHFQTSRSHGRHERSCSAEQPPEFIQCGKAFAYESGRQRHQIKHTGGKHHDCNQCGKDFRTRNAPQIHKRTHTGEKPYDCNQYGKAFARISHLRVHKRTHTGEKPYECNQCGKAFASSSDLQKHKRTHTGEKPYECNQCGKAFAQSSHLRIHKRTHAGDKRYECNQCGKAFTQSNNLQIHKGTHAGEKRYECNQCGKAFASSSDLQKHKRTHTGEKPYECNQCGKAFAKSCDLQKHKRTHTGEKPYECKQCGKAFAISYTLQIHNRTHTGEKPYECKQCGKAFAQSSNLRIHKQTHTGERLYECN", "length": 358 }, "evidence": [ { "id": "MGI:3702408", "url": "https://alliancegenome.org/gene/MGI:3702408#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080218-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080218-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ARR8-1", "protein_name": "Zinc finger protein 1010", "gene_name": "Zfp1010", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLITYDDVHVNFTQEEWALLDPSHKNLYKDVMVETYRNLTAIGYIWEEHTSEDHFQTSRSHGRHERSCSAEQPSEFIHCGKAFANESGSQRHQIKHTGEKQHDCNQCGKAFKRRSDLQIHKRTHTGEKPYECKQCGKAFSQSSHLRIHKRTHTGEKPYECKQCGKAFAQSSHLQIHKRTHTGEKPYECKQCGKAFAHSSHLHIHERTHTGEKPYECKQCGKGFARSGDLQKHKQTHTGEKPYECKQCGKAFSRKSVLQIHKRTHTGEKPYECKQCGKAFAQSSHLRIHKRAHTGLKPYECKQCGKAFAGSSGLQCHKRSHTGETPYECNQGGKPFEGSSGLEYNNRTQTAEKPYECNLCAKVLQEGVTFKEKRPYRRETL", "length": 381 }, "evidence": [ { "id": "MGI:3649811", "url": "https://alliancegenome.org/gene/MGI:3649811#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080218-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080218-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AW66-1", "protein_name": "Predicted gene 14322", "gene_name": "Gm14322", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLVTYDDVHVNFTQEEWALLHPSQKSLYKGVMLETYRNLTAIGYIWEEHTIEDHFQTSRSHGRHERSCSAEQPPEFIQCGKAFAYESGRQRHQIKHTGGKHHDCNQCGKDFRTRNVPQIHKRTHTGEKPYDCNQYGKAFARISHLRVHKRTHTGEKPYECNQCGKAFASSSDLQKHKRTHTGEKPYECNQCGKAFAQSSHLRIHKRTHAGDKRYECNQCGKAFTQSNNLQIHKGTHAGEKRYECNQCGKAFASSSDLQKHKRTHTGEKPYECNQCGKAFAKSCDLQKHKRTHTGEKPYECKQCGKAFAVSYTLQIHNRTHTGEKPYECKQCGKAFAQSSNLRIHKQTHTGERLYECN", "length": 358 }, "evidence": [ { "id": "MGI:3652185", "url": "https://alliancegenome.org/gene/MGI:3652185#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080218-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080218-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B8JJA7-1", "protein_name": "Zinc finger protein 942", "gene_name": "Zfp942", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNASLVNAPKGLLRFKDVAVDFSQEEWECLDCAQRALYMDVMLENYNNLFFVENLCIFPKYENGLDQDTQHIVHKHVTIQKKSYKYYEHGKIIQEYTQSVLYQDNFRDTHVESSNVNRHETGNTREPCKYKNCVNCLNLCSTIGLNQGLHIGKKEHNGTVLNKVFDSKQILGLKQTNSGKKPYRCSECSRCFTKKCKLRQHQTIHTGEKPYKCSECDKCFFYKYSLSIHQRFHTSEKLYKCSECDKCFTFKSVLRIHQRIHTGEKPYKCSKCEKSFTRKSNLRIHQRIHTGEKPYKCSECDKCFTFKNTHRIHQRIHTGEKPYKCSECEKSFTRKSHLRIHQRIHTGEKPYKCSECDKCFTYEHTLSNHQRIHTGQKPYKCSECDKCFTRKCNLIIHQKIHTGEKPYKCSECDKCFTHKGGLSIHQITHTGEKPYKCSECNKCFTHKGDLRRHQRIHSGEKPYKCSECDKCFTRKFSLRSHQRIHT", "length": 486 }, "evidence": [ { "id": "MGI:1920483", "url": "https://alliancegenome.org/gene/MGI:1920483#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080218-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080218-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z445-1", "protein_name": "Zinc finger protein 707", "gene_name": "Zfp707", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRRLAAAAALGEARRERCFRRGSALPERANGDAPPVPVTFRDVAVYFCREEWECLSPSQRTLYRNVMLENFRNLNELGCCSRRPGLITRLEQWDEPWVDDWDRSEFPDGQKSFCPGSRKVAHSRIGAGRGAALRKSALTSGKVRLPRATSGRRMDKREAFQNRICGKSHRKQPDLKEQGQSGPEGQPFICGICGKALSCHSRLAAHQTVHTGTRSFECLECGRTFRWASNLLRHQRNHTSEKPFCCELCGQAFSLKDRLAQHRKIHTEHRPYECGDCGKAFKQKSNLLRHKLVHTGEKPFYCDTCGKAFRTKENLSHHQRIHSGEKPYTCGECGKAFRWPKGFSIHQRLHLTKKFYQCEQCGKGFRHLGFFTRHQRTHGRGEV", "length": 384 }, "evidence": [ { "id": "HGNC:27815", "url": "https://alliancegenome.org/gene/HGNC:27815#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUS4-1", "protein_name": "Zinc finger protein 944", "gene_name": "Zfp944", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDVSLVNAPQGQLTFKDVAVDFSQEEWECLDCAQRALYMDVMLENYNNLFFVENHCVCPKYENVLDQDTQHIFHKHVNIQKKSCKCNDRGKDIYEYTQSVLYQDNFRDTHVKSSDVNRHETGNTREPCKYKNCVNCLNLCSIIGLNQGIHIGKKEHNGTVLDKVFDSKQILGLKQTNSGKKPYRCSECSRCFTKKCKLRQHQIIHTGEKPYRCSQCDKCFSQKCSHSTHKKIHTGEKPYKCTECDKCFTFKTDLRIHQRIHTGEKPYKCIECDKSFTQKGHLIIHQRIHTGEKPYKCSECDKCFTQKCSLTIHQRIHTGEKPYKCGKCEKCFTHKGDLRSHQRIHTGEKPYKCSECDKCFTHKRSLRSHQRIHTGEKPYKCSECDKCFTHKRSLSIHQIIHTEEKPYRCSGCDKIFNHKGDLRNHQRIHTGQKPYKCSECDKCFVHKYSLSIHQRIHTGEKPYKCNECNEFFRYKCSLRTHQKMHTLEHIYK", "length": 492 }, "evidence": [ { "id": "MGI:2442394", "url": "https://alliancegenome.org/gene/MGI:2442394#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080218-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080218-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96C28-1", "protein_name": "Zinc finger protein 707", "gene_name": "ZNF707", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDMAQEPVTFRDVAIYFSREEWACLEPSQRALYRDVMLDNFSSVAALGFCSPRPDLVSRLEQWEEPWVEDRERPEFQAVQRGPRPGARKSADPKRPCDHPAWAHKKTHVRRERAREGSSFRKGFRLDTDDGQLPRAAPERTDAKPTAFPCQVLTQRCGRRPGRRERRKQRAVELSFICGTCGKALSCHSRLLAHQTVHTGTKAFECPECGQTFRWASNLQRHQKNHTREKPFCCEACGQAFSLKDRLAQHRKVHTEHRPYSCGDCGKAFKQKSNLLRHQLVHTGERPFYCADCGKAFRTKENLSHHQRVHSGEKPYTCAECGKSFRWPKGFSIHRRLHLTKRFYECGHCGKGFRHLGFFTRHQRTHRHGEV", "length": 371 }, "evidence": [ { "id": "HGNC:27815", "url": "https://alliancegenome.org/gene/HGNC:27815#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080218-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080218-2#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96I27-1", "protein_name": "Zinc finger protein 625", "gene_name": "ZNF625", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGERLLESKKDHQHGEILTQVPDDMLKKKTPRVKSCGEVSVGHASLNRHHRADTGHKPYEYQEYGQKPYKCTYCKKAFSDLPYFRTHEWAHTGGKPYDCEECGKSFISRSSIRRHRIMHSGDGPYKCNFCGKALMCLSLYLIHKRTHTGEKPYECKQCGKAFSHSGSLRIHERTHTGEKPYECSECGKAFHSSTCLHAHKITHTGEKPYECKQCGKAFVSFNSVRYHERTHTGEKPYECKQCGKAFRSASHLRTHGRTHTGEKPYECKQCGKAFGCASSVKIHERTHTGEKPCSSNTSKGQGEKIA", "length": 306 }, "evidence": [ { "id": "MGI:3649811", "url": "https://alliancegenome.org/gene/MGI:3649811#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9BS34-1", "protein_name": "Zinc finger protein 670", "gene_name": "ZNF670", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSVSFEDVAVAFTQEEWALLDPSQKNLYRDVMQEIFRNLASVGNKSEDQNIQDDFKNPGRNLSSHVVERLFEIKEGSQYGETFSQDSNLNLNKKVSTGVKPCECSVCGKVFICHSALHRHILSHIGNKLFECEECPEKLYHCKQCGKAFISLTSVDRHMVTHTSNGPYKGPVYEKPFDFPSVFQMPQSTYTGEKTYKCKHCDKAFNYSSYLREHERTHTGEKPYACKKCGKSFTFSSSLRQHERSHTGEKPYECKECGKAFSRSTYLGIHERTHTGEKPYECIKCGKAFRCSRVLRVHERTHSGEKPYECKQCGKAFKYSSNLCEHERTHTGVKPYGCKECGKSFTSSSALRSHERTHTGEKPYECKKCGKAFSCSSSLRKHERAYMW", "length": 389 }, "evidence": [ { "id": "MGI:3702408", "url": "https://alliancegenome.org/gene/MGI:3702408#orthology", "database": "AGR" }, { "id": "MGI:3652185", "url": "https://alliancegenome.org/gene/MGI:3652185#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VHR4-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG7963", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSPPSGEFRCRVCLKQDELLVDIYEIVEEMQVDLCTLLETCGGIKVDRRDVQPMYLCQECTNELLIAAKFRKICVESEKLRDMAPEINIDTAEPLASEEIIIIDPSDYIEQLSAVEDPENEPIGVSRWNCQHCGAGFQLSEVLRRHIQEVHASITIIDCRERRRIFTKLGCYQVHNCSYAKTPKRGHKCLECGKCLQSASSLASHIRLHTDEWPFTCDQCAKAFRTNGALEVHQRRHKQVLQHKCLHCGRGFVESSNLRRHIVNRHTEERPHLCNVYQRSFSRVYMLELHLRTNTGERPYACQHRDKRFAQLGVLKIHERIHTGERLHRCQVCEKPFTRAGQLRKHALRHETGQ", "length": 354 }, "evidence": [ { "id": "MGI:3702408", "url": "https://alliancegenome.org/gene/MGI:3702408#orthology", "database": "AGR" }, { "id": "MGI:3652185", "url": "https://alliancegenome.org/gene/MGI:3652185#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PGY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGY2" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 104, "start_aa": "Phe", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 256, "end_pos": 258 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, 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This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z7S1-1", "uniprot_ac": "A0A8M6Z7S1", "uniprot_id": "A0A8M6Z7S1_DANRE", "mass": { "chemical_mass": 66398.0, "monoisotopic_mass": 66398.0 }, "refseq": { "ac": "XP_017212895", "name": "leucine-rich repeat transmembrane neuronal protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212895" }, "gene_names": [ { "name": "LOC100333709", "type": "recommended", "evidence": [ { "id": "A0A8M6Z7S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7S1" } ] }, { "name": "LOC100333709", "type": "synonym", "evidence": [ { "id": "XP_017212895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212895" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat transmembrane neuronal protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z7S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7S1/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat transmembrane neuronal protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017212895", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212895" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017212895", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212895" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7S1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7S1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100333709", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7S1", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z7S1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z7S1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100333709", "url": "https://www.ncbi.nlm.nih.gov/gene/100333709", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050541", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050541", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100333709", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333709", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z7S1", "url": "https://www.orthodb.org/?gene=A0A8M6Z7S1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366:SF120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366:SF120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24369:SF209", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24369:SF209", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017212895", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212895", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z7S1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7S1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z7S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7S1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TX48", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX48", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TX48-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX48-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G8T8", "url": "https://www.uniprot.org/uniprotkb/A0AC58G8T8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G8T8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G8T8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G8U6", "url": "https://www.uniprot.org/uniprotkb/A0AC58G8U6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G8U6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G8U6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGSLVRSRWLMIPLLVQAWLLASQGRVREKPCPRSCRCDGKIVYCESNAFRDVPKNVSIGCQGLSLRYNSLVNLRAGQFASLSQLVWLYLDHNYISGVDKQAFQGVRRLKELILSSNKITHLENSTFHSIPNLRNLDLSYNKLQILQPNQFQGLRKLLSLHIRSNSLKTVPMRVFQDCRNLEFLDLGYNRLRSLTRNAFAGLLKLTELHLEHNQFSKINFSHFPRLNNLRALYLQWNRIKSITQGITWTWTSLQKLDLSGNDLQVLDSSIFQCLPNLQTLNLDSNKLSNVSQEAISAWISLTTISLAGNIWECNPSLCPLVAWLRNFKGNKETTMICAGPKEIQGEKVIEAIDTHGICKTTPTPYLTMSSTVSSPSKAKRFPLPTMFRVNEKITRNNAVAPSPTAASPPVPEQDFEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPSSMKQLQQHSMVRKRRKKARETERTLSSPLQEYYVDYKPTNSETMDVLVNGTGPCTYTISGSRECEAPQQMSTLAFYRYEQPIVDYCQAHQPLHINRGFEPPPPPPSQSLEGLRAREHLHPSVPAAPRTDTHTLPQ", "length": 585, "header": "tr|A0A8M6Z7S1-1|A0A8M6Z7S1_DANRE Isoform 1 of Leucine-rich repeat transmembrane neuronal protein 4 isoform X1 OS=Danio rerio OX=7955 GN=LOC100333709 PE=3 SV=1 CANONICAL=A0A8M6Z7S1-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z7S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7S1/entry#A0A8M6Z7S1-1", "sequence": { "sequence": "MGSLVRSRWLMIPLLVQAWLLASQGRVREKPCPRSCRCDGKIVYCESNAFRDVPKNVSIGCQGLSLRYNSLVNLRAGQFASLSQLVWLYLDHNYISGVDKQAFQGVRRLKELILSSNKITHLENSTFHSIPNLRNLDLSYNKLQILQPNQFQGLRKLLSLHIRSNSLKTVPMRVFQDCRNLEFLDLGYNRLRSLTRNAFAGLLKLTELHLEHNQFSKINFSHFPRLNNLRALYLQWNRIKSITQGITWTWTSLQKLDLSGNDLQVLDSSIFQCLPNLQTLNLDSNKLSNVSQEAISAWISLTTISLAGNIWECNPSLCPLVAWLRNFKGNKETTMICAGPKEIQGEKVIEAIDTHGICKTTPTPYLTMSSTVSSPSKAKRFPLPTMFRVNEKITRNNAVAPSPTAASPPVPEQDFEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPSSMKQLQQHSMVRKRRKKARETERTLSSPLQEYYVDYKPTNSETMDVLVNGTGPCTYTISGSRECEAPQQMSTLAFYRYEQPIVDYCQAHQPLHINRGFEPPPPPPSQSLEGLRAREHLHPSVPAAPRTDTHTLPQ", "length": 585, "header": "tr|A0A8M6Z7S1-1|A0A8M6Z7S1_DANRE Isoform 1 of Leucine-rich repeat transmembrane neuronal protein 4 isoform X1 OS=Danio rerio OX=7955 GN=LOC100333709 PE=3 SV=1 CANONICAL=A0A8M6Z7S1-1" }, "locus": {} }, { "isoform_ac": "A0AB32TX48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7S1/entry#A0AB32TX48-1", "sequence": { "sequence": "MGSLVRSRWLMIPLLVQAWLLASQGRVREKPCPRSCRCDGKIVYCESNAFRDVPKNVSIGCQGLSLRYNSLVNLRAGQFASLSQLVWLYLDHNYISGVDKQAFQGVRRLKELILSSNKITHLENSTFHSIPNLRNLDLSYNKLQILQPNQFQGLRKLLSLHIRSNSLKTVPMRVFQDCRNLEFLDLGYNRLRSLTRNAFAGLLKLTELHLEHNQFSKINFSHFPRLNNLRALYLQWNRIKSITQGITWTWTSLQKLDLSGNDLQVLDSSIFQCLPNLQTLNLDSNKLSNVSQEAISAWISLTTISLAGNIWECNPSLCPLVAWLRNFKGNKETTMICAGPKEIQGEKVIEAIDTHGICKTTPTPYLTMSSTVSSPSKAKRFPLPTMFRVNEKITRNNAVAPSPTAASPPVPEQDFEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPSSMKQLQQHSMVRKRRKKARETERTLSSPLQEYYVDYKPTNSETMDVLVNGTGPCTYTISGSRECEV", "length": 516, "header": "tr|A0AB32TX48-1|A0A8M6Z7S1_DANRE Computationally mapped isoform of Leucine-rich repeat transmembrane neuronal protein 4 isoform X1 OS=Danio rerio OX=7955 GN=LOC100333709 PE=3 SV=1 CANONICAL=A0A8M6Z7S1-1" }, "locus": {} }, { "isoform_ac": "A0AC58G8T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7S1/entry#A0AC58G8T8-1", "sequence": { "sequence": "MIPLLVQAWLLASQGRVREKPCPRSCRCDGKIVYCESNAFRDVPKNVSIGCQGLSLRYNSLVNLRAGQFASLSQLVWLYLDHNYISGVDKQAFQGVRRLKELILSSNKITHLENSTFHSIPNLRNLDLSYNKLQILQPNQFQGLRKLLSLHIRSNSLKTVPMRVFQDCRNLEFLDLGYNRLRSLTRNAFAGLLKLTELHLEHNQFSKINFSHFPRLNNLRALYLQWNRIKSITQGITWTWTSLQKLDLSGNDLQVLDSSIFQCLPNLQTLNLDSNKLSNVSQEAISAWISLTTISLAGNIWECNPSLCPLVAWLRNFKGNKETTMICAGPKEIQGEKVIEAIDTHGICKTTPTPYLTMSSTVSSPSKAKRFPLPTMFRVNEKITRNNAVAPSPTAASPPVPEQDFEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPSSMKQLQQHSMVRKRRKKARETERTLSSPLQEYYVDYKPTNSETMDVLVNGTGPCTYTISGSRECEAPQQMSTLAFYRYEQPIVDYCQAHQPLHINRGFEPPPPPPSQSLEGLRAREHLHPSVPAAPRTDTHTLPQ", "length": 575, "header": "tr|A0AC58G8T8-1|A0AC58G8T8_DANRE Computationally mapped isoform of Leucine-rich repeat transmembrane neuronal protein 4 isoform X2 OS=Danio rerio OX=7955 GN=LOC100333709 PE=3 SV=1 CANONICAL=A0A8M6Z7S1-1" }, "locus": {} }, { "isoform_ac": "A0AC58G8U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7S1/entry#A0AC58G8U6-1", "sequence": { "sequence": "MIPLLVQAWLLASQGRVREKPCPRSCRCDGKIVYCESNAFRDVPKNVSIGCQGLSLRYNSLVNLRAGQFASLSQLVWLYLDHNYISGVDKQAFQGVRRLKELILSSNKITHLENSTFHSIPNLRNLDLSYNKLQILQPNQFQGLRKLLSLHIRSNSLKTVPMRVFQDCRNLEFLDLGYNRLRSLTRNAFAGLLKLTELHLEHNQFSKINFSHFPRLNNLRALYLQWNRIKSITQGITWTWTSLQKLDLSGNDLQVLDSSIFQCLPNLQTLNLDSNKLSNVSQEAISAWISLTTISLAGNIWECNPSLCPLVAWLRNFKGNKETTMICAGPKEIQGEKVIEAIDTHGICKTTPTPYLTMSSTVSSPSKAKRFPLPTMFRVNEKITRNNAVAPSPTAASPPVPEQDFEHVSFHKIIAGSVALFLSVAMILLVIYVSWKRYPSSMKQLQQHSMVRKRRKKARETERTLSSPLQEYYVDYKPTNSETMDVLVNGTGPCTYTISGSRECEV", "length": 506, "header": "tr|A0AC58G8U6-1|A0AC58G8U6_DANRE Computationally mapped isoform of Leucine-rich repeat transmembrane neuronal protein 4 isoform X4 OS=Danio rerio OX=7955 GN=LOC100333709 PE=3 SV=1 CANONICAL=A0A8M6Z7S1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 404, "start_aa": "Thr", "end_pos": 404, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr404", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100333709", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333709", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7S1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7S1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 404 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 219, "end_pos": 221 }, { "start_pos": 289, "end_pos": 291 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z8J5-1", "uniprot_ac": "A0A8M6Z8J5", "uniprot_id": "A0A8M6Z8J5_DANRE", "mass": { "chemical_mass": 197274.0, "monoisotopic_mass": 197274.0 }, "refseq": { "ac": "XP_009302857", "name": "A-kinase anchor protein 11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302857" }, "gene_names": [ { "name": "akap11", "type": "recommended", "evidence": [ { "id": "A0A8M6Z8J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5" } ] }, { "name": "akap11", "type": "synonym", "evidence": [ { "id": "XP_009302857", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302857" } ] } ], "protein_names": [ { "name": "A-kinase anchor protein 11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_009302857", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302857" }, { "id": "A0A8M6Z8J5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_009302857.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009302857", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302857" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8J5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "akap11", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090804-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090804-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "558595", "url": "https://www.ncbi.nlm.nih.gov/gene/558595", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008382", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008382", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558595", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558595", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z8J5", "url": "https://www.orthodb.org/?gene=A0A8M6Z8J5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10226:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10226:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_009302857", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302857", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8J5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TXI9", "url": "https://www.uniprot.org/uniprotkb/A0AB32TXI9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TXI9-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TXI9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TXU5", "url": "https://www.uniprot.org/uniprotkb/A0AB32TXU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TXU5-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TXU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U1T3", "url": "https://www.uniprot.org/uniprotkb/A0AB32U1T3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U1T3-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32U1T3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090804-1", "url": "https://zfin.org/ZDB-GENE-090804-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDACARIRGIPIKSRATMKKETIREGSNPCLKSLLKHKKELCNVVVELHNKEPQCLSEVHYVCLPSHAEGEDFTLQALTSLSTEMMELLRSLHVHNLKDEEILLLKDPKRPFERKDSVSQACSRALCILRHSPTSQTNVCTMLGLLARYSAGIRYALELQVLHRGNSESCQAEDDDTNQSVSSIEEDFVTALEHLEEDDTGSHGHRNQRDVASQTVPSHLKDLTGSHIILSSIPKKSSRREKAQAKVSETVIKSIAFQRNSESPCVLGSPPKGRATATSLTESDDSDCSSPSPIIFLDEVGYQKSLKAKLDIPKIPVLKDGVEDSDSEVSEFFDSFDQFDELDQSFDSIVKAHKEHPGQTEKHVDKSGCKFVSRGCSTTGMNPHKFDHRTLPANVKKPTPLKPGSPYSIQSDSPESPRLARTPCEESGPLFSPVRSSAFSPLGEGGSLEYFWKGDSEGSELRKPQDLCSLYKTYSDFANSLSKEILGSVCGYSSPVDFNINKNLSCVCHKEFQNTNGHLMKLSDIQETVTITKSQSQSLKDGIQKFATDLVERSLGSALRDLQKGVSSCTTTLCHMAARLTSSVFQMAFHEIGMRHAYVLKERAINGLANFLVGEAISGALKEFLFVKKQIFNNTVTRFAADLAEELVFEGIMEVCQFSHPSTPLTPSDWSFEQEEEVVSSYASDLSESVLQEAFIELSQADVTFTTQAAISVSVDNICYVSAEDSSHITKTCSSQSSYLGSQIVTEVANQEQGGCTVKKALYCVSGMASCVPVPVAGKVISHVHSSDEPSQYKHSIDHVCQTSPKRTICCQGEAASSSSDISATTQTETSPGPARIQNASVEEIVSSPSTENDSSKPSIGKTFQNFSGNMVDTIVGEAFDLMHSSTKVKKKVEDCADFLNKTIAARISTPTHGVVKLNDVSGQKGCHQTPFHLTSKGSCDTSSRTVRPVSKLTPEVRSVARRDVLEVPSFEFHSCGGRRAAAEDSLSSNSGSKSVEIPSTPPSSPQQPSDEHSEKQIRQFSKKLKGTLAKEFSPATPPPTPYYPPVTDVKEKGSVSDKADFMLKLIRSLSEEAVSNEDEEEDQEDGPHTRNSQEKMSPSVRSRMIERSALHYAERLACHIVSMATEMDTLSLGDVKKPVGDESKDSIALHSAQFSEQTLNSLWTYAGEVAGEVINDVKRISSTHCRHKTIKRGSVYSADKHQNGEGLLGSLTCQWSSDVQASGGSSGMSSEYPSCESVTDEYAGYLIKVLKKEGGNRELILDQYATRLAYRSIKSGLAHAARKIKQRSPLRLHSSRRLHNDPSPEVSQISISMSPHTAVTDGKDGSSCESLPCACQDSQDLSSNEYVELVSFAESLAYNITCDVTRKLRMSSVRMPKSLTDSCLYRKSTVEDVPENLIKGTFSCSPLPFAEANRLYHSTSSLNDGKSNSGVMQVIEHYARKIVDDTLEMTLGPACVQAAGDRRALEPNSFTEKLAEACETCRYCQGRDCLFCSRDGRRGFQGLKIRRQQESGAVTGLDIPRIHIDLEKRTAFAEEMVSSAIEKAKKELSCTSLNADSGIGHDGASFAESLTTEIMTSALSNACQTINLGTPRKEGGNVTESTVSQQLSLSVGDDSLGSWSNLSFEEDHPDESSSFHHLSDSVCVFLSPSSNGNSSSWSSLGLEGEVYEEHLSFSPSDSDCPEEKEAEAKEESAGAVRVEREHGQALLVVSTDVQGRAVDPQLMAVLQWIAASVADLSMMQLSQFAAQEVQQLPVVAQRLREREFRVGDLLQALLRYIEEEEPESGDSTHNHKSLFQWLLEHA", "length": 1803, "header": "tr|A0A8M6Z8J5-1|A0A8M6Z8J5_DANRE Isoform 1 of A-kinase anchor protein 11 isoform X1 OS=Danio rerio OX=7955 GN=akap11 PE=4 SV=2 CANONICAL=A0A8M6Z8J5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z8J5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5/entry#A0A8M6Z8J5-1", "sequence": { "sequence": "MDACARIRGIPIKSRATMKKETIREGSNPCLKSLLKHKKELCNVVVELHNKEPQCLSEVHYVCLPSHAEGEDFTLQALTSLSTEMMELLRSLHVHNLKDEEILLLKDPKRPFERKDSVSQACSRALCILRHSPTSQTNVCTMLGLLARYSAGIRYALELQVLHRGNSESCQAEDDDTNQSVSSIEEDFVTALEHLEEDDTGSHGHRNQRDVASQTVPSHLKDLTGSHIILSSIPKKSSRREKAQAKVSETVIKSIAFQRNSESPCVLGSPPKGRATATSLTESDDSDCSSPSPIIFLDEVGYQKSLKAKLDIPKIPVLKDGVEDSDSEVSEFFDSFDQFDELDQSFDSIVKAHKEHPGQTEKHVDKSGCKFVSRGCSTTGMNPHKFDHRTLPANVKKPTPLKPGSPYSIQSDSPESPRLARTPCEESGPLFSPVRSSAFSPLGEGGSLEYFWKGDSEGSELRKPQDLCSLYKTYSDFANSLSKEILGSVCGYSSPVDFNINKNLSCVCHKEFQNTNGHLMKLSDIQETVTITKSQSQSLKDGIQKFATDLVERSLGSALRDLQKGVSSCTTTLCHMAARLTSSVFQMAFHEIGMRHAYVLKERAINGLANFLVGEAISGALKEFLFVKKQIFNNTVTRFAADLAEELVFEGIMEVCQFSHPSTPLTPSDWSFEQEEEVVSSYASDLSESVLQEAFIELSQADVTFTTQAAISVSVDNICYVSAEDSSHITKTCSSQSSYLGSQIVTEVANQEQGGCTVKKALYCVSGMASCVPVPVAGKVISHVHSSDEPSQYKHSIDHVCQTSPKRTICCQGEAASSSSDISATTQTETSPGPARIQNASVEEIVSSPSTENDSSKPSIGKTFQNFSGNMVDTIVGEAFDLMHSSTKVKKKVEDCADFLNKTIAARISTPTHGVVKLNDVSGQKGCHQTPFHLTSKGSCDTSSRTVRPVSKLTPEVRSVARRDVLEVPSFEFHSCGGRRAAAEDSLSSNSGSKSVEIPSTPPSSPQQPSDEHSEKQIRQFSKKLKGTLAKEFSPATPPPTPYYPPVTDVKEKGSVSDKADFMLKLIRSLSEEAVSNEDEEEDQEDGPHTRNSQEKMSPSVRSRMIERSALHYAERLACHIVSMATEMDTLSLGDVKKPVGDESKDSIALHSAQFSEQTLNSLWTYAGEVAGEVINDVKRISSTHCRHKTIKRGSVYSADKHQNGEGLLGSLTCQWSSDVQASGGSSGMSSEYPSCESVTDEYAGYLIKVLKKEGGNRELILDQYATRLAYRSIKSGLAHAARKIKQRSPLRLHSSRRLHNDPSPEVSQISISMSPHTAVTDGKDGSSCESLPCACQDSQDLSSNEYVELVSFAESLAYNITCDVTRKLRMSSVRMPKSLTDSCLYRKSTVEDVPENLIKGTFSCSPLPFAEANRLYHSTSSLNDGKSNSGVMQVIEHYARKIVDDTLEMTLGPACVQAAGDRRALEPNSFTEKLAEACETCRYCQGRDCLFCSRDGRRGFQGLKIRRQQESGAVTGLDIPRIHIDLEKRTAFAEEMVSSAIEKAKKELSCTSLNADSGIGHDGASFAESLTTEIMTSALSNACQTINLGTPRKEGGNVTESTVSQQLSLSVGDDSLGSWSNLSFEEDHPDESSSFHHLSDSVCVFLSPSSNGNSSSWSSLGLEGEVYEEHLSFSPSDSDCPEEKEAEAKEESAGAVRVEREHGQALLVVSTDVQGRAVDPQLMAVLQWIAASVADLSMMQLSQFAAQEVQQLPVVAQRLREREFRVGDLLQALLRYIEEEEPESGDSTHNHKSLFQWLLEHA", "length": 1803, "header": "tr|A0A8M6Z8J5-1|A0A8M6Z8J5_DANRE Isoform 1 of A-kinase anchor protein 11 isoform X1 OS=Danio rerio OX=7955 GN=akap11 PE=4 SV=2 CANONICAL=A0A8M6Z8J5-1" }, "locus": {} }, { "isoform_ac": "A0AB32TXI9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5/entry#A0AB32TXI9-1", "sequence": { "sequence": "MDACARIRGIPIKSRATMKKETIREGSNPCLKSLLKHKKELCNVVVELHNKEPQCLSEVHYVCLPSHAEGEDFTLQALTSLSTEMMELLRSLHVHNLKDEEILLLKDPKRPFERKDSVSQACSRALCILRHSPTSQTNVCTMLGLLARYSAGIRYALELQVLHRGNSESCQAEDDDTNQSVSSIEEDFVTALEHLEEDDTGSHGHRNQRDVASQTVPSHLKDLTGSHIILSSIPKKSSRREKAQAKVSETVIKSIAFQRNSESPCVLGSPPKGRATATSLTESDDSDCSSPSPIIFLDEVGYQKSLKAKLDIPKIPVLKDGVEDSDSEVSEFFDSFDQFDELDQSFDSIVKAHKEHPGQTEKHVDKSGCKFVSRGCSTTGMNPHKFDHRTLPANVKKPTPLKPGSPYSIQSDSPESPRLARTPCEESGPLFSPVRSSAFSPLGEGGSLEYFWKGDSEGSELRKPQDLCSLYKTYSDFANSLSKEILGSVCGYSSPVDFNINKNLSCVCHKEFQNTNGHLMKLSDIQETVTITKSQSQSLKDGIQKFATDLVERSLGSALRDLQKGVSSCTTTLCHMAARLTSSVFQMAFHEIGMRHAYVLKERAINGLANFLVGEAISGALKEFLFVKKQIFNNTVTRFAADLAEELVFEGIMEVCQFSHPSTPLTPSDWSFEQEEEVVSSYASDLSESVLQEAFIELSQADVTFTTQAAISVSVDNICYVSAEDSSHITKTCSSQSSYLGSQIVTEVANQEQGGCTVKKALYCVSGMASCVPVPVAGKVISHVHSSDEPSQYKHSIDHVCQTSPKRTICCQGEAASSSSDISATTQTETSPGPARIQNASVEEIVSSPSTENDSSKPSIGKTFQNFSGNMVDTIVGEAFDLMHSSTKVKKKVEDCADFLNKTIAARISTPTHGVVKLNDVSGQKGCHQTPFHLTSKGSCDTSSRTVRPVSKLTPEVRSVARRDVLEVPSFEFHSCGGRRAAAEDSLSSNSGSKSVEIPSTPPSSPQQPSDEHSEKQIRQFSKKLKGTLAKEFSPATPPPTPYYPPVTDVKEKGSVSDKADFMLKLIRSLSEEAVSNEDEEEDQEDGPHTRNSQEKMSPSVRSRMIERSALHYAERLACHIVSMATEMDTLSLGDVKKPVGDESKDSIALHSAQFSEQTLNSLWTYAGEVAGEVINDVKRISSTHCRHKTIKRGSVYSADKHQNGEGLLGSLTCQWSSDVQASGGSSGMSSEYPSCESVTDEYAGYLIKVLKKEGGNRELILDQYATRLAYRSIKSGLAHAARKIKQRSPLRLHSSRRLHNDPSPEVSQISISMSPHTAVTDGKDGSSCESLPCACQDSQDLSSNEYVELVSFAESLAYNITCDVTRKLRMSSVRMPKSLTDSCLYRKSTVEDVPENLIKGTFSCSPLPFAEANRLYHSTSSLNDGKSNSGVMQVIEHYARKIVDDTLEMTLGPACVQAAGDRRALEPNSFTEKLAEACETCRYCQGRDCLFCSRDGRRGFQGLKIRRQQESGAVTGLDIPRIHIDLEKRTAFAEEMVSSAIEKAKKELSCTSLNADSGIGHDGASFAESLTTEIMTSALSNACQTINLGTPRKEGGNVTESTVSQQLSLSVGDDSLGSWSNLSFEEDHPDESSSFHHLSDSDCPEEKEAEAKEESAGAVRVEREHGQALLVVSTDVQGRAVDPQLMAVLQWIAASVADLSMMQLSQFAAQEVQQLPVVAQRLREREFRVGDLLQALLRYIEEEEPESGDSTHNHKSLFQWLLEHA", "length": 1766, "header": "tr|A0AB32TXI9-1|A0A8M6Z8J5_DANRE Computationally mapped isoform of A-kinase anchor protein 11 isoform X1 OS=Danio rerio OX=7955 GN=akap11 PE=4 SV=2 CANONICAL=A0A8M6Z8J5-1" }, "locus": {} }, { "isoform_ac": "A0AB32TXU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5/entry#A0AB32TXU5-1", "sequence": { "sequence": "MDACARIRGIPIKSRATMKKETIREGSNPCLKSLLKHKKELCNVVVELHNKEPQCLSEVHYVCLPSHAEGEDFTLQALTSLSTEMMELLRSLHVHNLKDEEILLLKDPKRPFERKDSVSQACSRALCILRHSPTSQTNVCTMLGLLARYSAGIRYALELQVLHRGNSESCQAEDDDTNQSVSSIEEDFVTALEHLEEDDTGSHGHRNQRDVASQTVPSHLKDLTGSHIILSSIPKKSSRREKAQAKVSETVIKSIAFQRNSESPCVLGSPPKGRATATSLTESDDSDCSSPSPIIFLDEVGYQKSLKAKLDIPKIPVLKDGVEDSDSEVSEFFDSFDQFDELDQSFDSIVKAHKEHPGQTEKHVDKSGCKFVSRGCSTTGMNPHKFDHRTLPANVKKPTPLKPGSPYSIQSDSPESPRLARTPCEESGPLFSPVRSSAFSPLGEGGSLEYFWKGDSEGSELRKPQDLCSLYKTYSDFANSLSKEILGSVCGYSSPVDFNINKNLSCVCHKEFQNTNGHLMKLSDIQETVTITKSQSQSLKDGIQKFATDLVERSLGSALRDLQKGVSSCTTTLCHMAARLTSSVFQMAFHEIGMRHAYVLKERAINGLANFLVGEAISGALKEFLFVKKQIFNNTVTRFAADLAEELVFEGIMEVCQFSHPSTPLTPSDWSFEQEEEVVSSYASDLSESVLQEAFIELSQADVTFTTQAAISVSVDNICYVSAEDSSHITKTCSSQSSYLGSQIVTEVANQEQGGCTVKKALYCVSGMASCVPVPVAGKVISHVHSSDEPSQYKHSIDHVCQTSPKRTICCQGEAASSSSDISATTQTETSPGPARIQNASVEEIVSSPSTENDSSKPSIGKTFQNFSGNMVDTIVGEAFDLMHSSTKVKKKVEDCADFLNKTIAARISTPTHGVVKLNDVSGQKGCHQTPFHLTSKGSCDTSSRTVRPVSKLTPEVRSVARRDVLEVPSFEFHSCGGRRAAAEDSLSSNSGSKSVEIPSTPPSSPQQPSDEHSEKQIRQFSKKLKGTLAKEFSPATPPPTPYYPPVTDVKEKGSVSDKADFMLKLIRSLSEEAVSNEDEEEDQEDGPHTRNSQEKMSPSVRSRMIERSALHYAERLACHIVSMATEMDTLSLGDVKKPVGDESKDSIALHSAQFSEQTLNSLWTYAGEVAGEVINDVKRISSTHCRHKTIKRGSVYSADKHQNGEGLLGSLTCQWSSDVQASGGSSGMSSEYPSCESVTDEYAGYLIKVLKKEGGNRELILDQYATRLAYRSIKSGLAHAARKIKQRSPLRLHSSRRLHNDPSPEVSQISISMSPHTAVTDGKDGSSCESLPCACQDSQDLSSNEYVELVSFAESLAYNITCDVTRKLRMSSVRMPKSLTDSCLYRKSTVEDVPENLIKGTFSCSPLPFAEANRLYHSTSSLNDGKSNSGVMQVIEHYARKIVDDTLEMTLGPACVQAAGDRRALEPNSFTEKLAEACETCRYCQGRDCLFCSRDGRRGFQGLKIRRQQESGAVTGLDIPRIHIDLEKRTAFAEEMVSSAIEKAKKELSCTSLNADSGIGHDGASFAESLTTEIMTSALSNACQTINLGTPRKEGGNVTESTVSQQLSLSVGDDSLGSWSNLSFEEDHPDESSSFHHLSDSSNGNSSSWSSLGLEGEVYEEHLSFSPSDSDCPEEKEAEAKEESAGAVRVEREHGQALLVVSTDVQGRAVDPQLMAVLQWIAASVADLSMMQLSQFAAQEVQQLPVVAQRLREREFRVGDLLQALLRYIEEEEPESGDSTHNHKSLFQWLLEHA", "length": 1795, "header": "tr|A0AB32TXU5-1|A0A8M6Z8J5_DANRE Computationally mapped isoform of A-kinase anchor protein 11 isoform X1 OS=Danio rerio OX=7955 GN=akap11 PE=4 SV=2 CANONICAL=A0A8M6Z8J5-1" }, "locus": {} }, { "isoform_ac": "A0AB32U1T3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5/entry#A0AB32U1T3-1", "sequence": { "sequence": "MDACARIRGIPIKSRATMKKETIREGSNPCLKSLLKHKKELCNVVVELHNKEPQCLSEVHYVCLPSHAEGEDFTLQALTSLSTEMMELLRSLHVHNLKDEEILLLKDPKRPFERKDSVSQACSRALCILRHSPTSQTNVCTMLGLLARYSAGIRYALELQVLHRGNSESCQAEDDDTNQSVSSIEEDFVTALEHLEEDDTGSHGHRNQRDVASQTVPSHLKDLTGSHIILSSIPKKSSRREKAQAKVSETVIKSIAFQRNSESPCVLGSPPKGRATATSLTESDDSDCSSPSPIIFLDEVGYQKSLKAKLDIPKIPVLKDGVEDSDSEVSEFFDSFDQFDELDQSFDSIVKAHKEHPGQTEKHVDKSGCKFVSRGCSTTGMNPHKFDHRTLPANVKKPTPLKPGSPYSIQSDSPESPRLARTPCEESGPLFSPVRSSAFSPLGEGGSLEYFWKGDSEGSELRKPQDLCSLYKTYSDFANSLSKEILGSVCGYSSPVDFNINKNLSCVCHKEFQNTNGHLMKLSDIQETVTITKSQSQSLKDGIQKFATDLVERSLGSALRDLQKGVSSCTTTLCHMAARLTSSVFQMAFHEIGMRHAYVLKERAINGLANFLVGEAISGALKEFLFVKKQIFNNTVTRFAADLAEELVFEGIMEVCQFSHPSTPLTPSDWSFEQEEEVVSSYASDLSESVLQEAFIELSQADVTFTTQAAISVSVDNICYVSAEDSSHITKTCSSQSSYLGSQIVTEVANQEQGGCTVKKALYCVSGMASCVPVPVAGKVISHVHSSDEPSQYKHSIDHVCQTSPKRTICCQGEAASSSSDISATTQTETSPGPARIQNASVEEIVSSPSTENDSSKPSIGKTFQNFSGNMVDTIVGEAFDLMHSSTKVKKKVEDCADFLNKTIAARISTPTHGVVKLNDVSGQKGCHQTPFHLTSKGSCDTSSRTVRPVSKLTPEVRSVARRDVLEVPSFEFHSCGGRRAAAEDSLSSNSGSKSVEIPSTPPSSPQQPSDEHSEKQIRQFSKKLKGTLAKEFSPATPPPTPYYPPVTDVKEKGSVSDKADFMLKLIRSLSEEAVSNEDEEEDQEDGPHTRNSQEKMSPSVRSRMIERSALHYAERLACHIVSMATEMDTLSLGDVKKPVGDESKDSIALHSAQFSEQTLNSLWTYAGEVAGEVINDVKRISSTHCRHKTIKRGSVYSADKHQNGEGLLGSLTCQWSSDVQASGGSSGMSSEYPSCESVTDEYAGYLIKVLKKEGGNRELILDQYATRLAYRSIKSGLAHAARKIKQRSPLRLHSSRRLHNDPSPEVSQISISMSPHTAVTDGKDGSSCESLPCACQDSQDLSSNEYVELVSFAESLAYNITCDVTRKLRMSSVRMPKSLTDSCLYRKSTVEDVPENLIKGTFSCSPLPFAEANRLYHSTSSLNDGKSNSGVMQVIEHYARKIVDDTLEMTLGPACVQAAGDRRALEPNSFTEKLAEACETCRYCQGRDCLFCSRDGRRGFQGLKIRRQQESGAVTGLDIPRIHIDLEKRTAFAEEMVSSAIEKAKKELSCTSLNADSGIGHDGASFAESLTTEIMTSALSNACQTINLGTPRKEGGNVTESTVSQQLSLSVGDDSLGSWSNLSFEEDHPDESSSFHHLSDSNGNSSSWSSLGLEGEVYEEHLSFSPSDSDCPEEKEAEAKEESAGAVRVEREHGQALLVVSTDVQGRAVDPQLMAVLQWIAASVADLSMMQLSQFAAQEVQQLPVVAQRLREREFRVGDLLQALLRYIEEEEPESGDSTHNHKSLFQWLLEHA", "length": 1794, "header": "tr|A0AB32U1T3-1|A0AB32U1T3_DANRE Computationally mapped isoform of A-kinase anchor protein 11 isoform X3 OS=Danio rerio OX=7955 GN=akap11 PE=4 SV=1 CANONICAL=A0A8M6Z8J5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1041, "start_aa": "Thr", "end_pos": 1041, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1041", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:558595", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558595", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q777-1", "protein_name": "A kinase anchor protein 11", "gene_name": "Akap11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAFQPLRSSHLKSKASVRKSFSEDVFRSVKSLLQSEKELCSVSGGECLNQDEHPQLTEVTFLGFNEETDAAHIQDLAAVSLELPDLLNSLHFCSLSENEIICMKDTSKSSNVSSSPLNQSHHSGMLCVMRVSPTLPGLRIDFIFSLLSKYAAGIRHTLDMHAHPQHHLETTDEDDDDTNQSVSSIEDDFVTAFEQLEEEENAKLYNDEINIATLRSRCDAASQTTSGHHLESHDLKVLVSYGSPKSLAKPSPSVNVLGRKEAASVKTSVTTSVSEPWTQRSLYRCPSASDKDKDTQETFFPSPVYSSESECSSPSPVIFLDEEGYQKSLKAKLELPEIPVTKDDVEDSDSEVSEFFDSFDQFDELEQTLETYLLMEDPIIGKSSQKIGHKYEKSCMNPQKFKFERPALPANVRKPTPRKPESPYGHLSDAPDSPRPVMTSEDSGLFSPIRTSAFSPPGSCTPAEWFCQTDTSENRNHENYCTYEDYANNLSCEVLGSVLHTQHANTMSDINSIKRGRNHTVTFKYGDSDQKSKCKKSSVITGSVQKFAADLVGKSLGSAFKDLQKGVSSCTNTLCHLAVKLTSSVFQMAFNELRRQCAFSLKERAIGSLASLLVSDALSNALKDLQYVKKQMFTNTVARFAADLAEELVFEGIMEVCQFSCPQTPASSQCQSFDFEDKVVKSYAKDLSESVIQEAFIELSQTNVTFTTKAAVNVSMGNVKYVSAESVSPTQTFTFSSSFSGQAVMMTKPMQEHKKEYTVQQALFCTSGIVTSIPVPLAGSALLPYHMSSTLYPSKCLSSEPSKASGGSTQEHIAIERSAEEVDCLRSTCLPSELNPCNQNDFKPTNGDIDRQSPSKLMSGPVIISNFSAAMVHTIVNETLESMTSFKATKTIDTNADYLTKTIKGKACSPSLCDQAAPQENKASSKDMFAEQLSKSIIKHSLDKSKSMLPNRDKKPGSKEHVLVLGEESQMTLGETPKFLDFSDNSPHRSLLVGNYCVAECKDSVGFGFSLEALPPCSMMTNQKSDLKEVVKDKEVTRHNLNNTALEPMPFGQESSFRHSQTFSSAVLTCVDGLHEEDKQKIRDRNVIPDTPPSTPLVPSQTSSEWDIKTLSKQLKGELAKEFAPATPPSTPHNSSVGSLSENEQTTIEKEEFMLKLMRSLSEEVESSEGEEHPGMHVKAEHPGKKVQFAEAFATHIISLATEAAASHLDHETTQEFKVQNPHLNVPSQRNVLPALSHSDESIQTCTFASDMAADVIAEAEKIANARSCMLFRHERNICHVEGGRGKAEEKLDVEDVAHPREVDTCVLSLPSGMPGLTYKYPSCESVTDEYAGHVIQVLQQQGGSGELIMEQYASRLAYRSVTAAAREAAKTVKMKCGSKLFPLHGCHGKTNKELLVFSSKERHQEVDRQRKRNGSHLCKYQTCERTQDPCRNELSELYSFSASLASSITRDAKKQLTAPKVDLPKSSTDGCFFEKSECVDSSENVTGPERSKSCQPLQSHGFCQNTGYLSGYSCAENAQAIEQYARKVVGDTLELSLGPTVFHNSETTASADRITYAEKLSPLINEACRYCDLKEFHGCTRNSAQLFSKQSPCASAKPSSRSKLSSIRQKSRIFHLDVPQIHVNLDKRAVLAEKIVAEAIEKAERELSNTSLAADSGIGQDGISFAESLTTEIMTTAVTNAGHAVSSSREIEDFQSTESLGSQQMNLSVGEDSTGSWSNLSFEDDHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDSDGSDDGDDEQEDGVEDLQQNGKTLLIMNIDMEPGAVDPQLRIILQWLIASEAEVAELYFQDSAKKEFILLSKQLQEKGWKVGDVLQAVLKYYEVVEKPSREERCKSLFDWLLENAQNRLQTSMLV", "length": 1894 }, "evidence": [ { "id": "HGNC:369", "url": "https://alliancegenome.org/gene/HGNC:369#orthology", "database": "AGR" }, { "id": "MGI:2684060", "url": "https://alliancegenome.org/gene/MGI:2684060#orthology", "database": "AGR" }, { "id": "RGD:2079", "url": "https://alliancegenome.org/gene/RGD:2079#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090804-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090804-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62924-1", "protein_name": "A-kinase anchor protein 11", "gene_name": "Akap11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQKMQCHLRRPLHSSSSFSSQAVMMTKPMQEHKKEYTAQQALFRPSGIVTSIPVPLAGSALLPYHVSSTLYQSKSLSSSEHNKANGGSPQEHIAMESSAEEVDCFKNTCLPSELSPCSQNDFKPTNGDIDMQSPSKLMSGSMIISNFSTAMVHTIVNETLESMTSFKATKPVDTNADYLTKTIKGKPVLSLCDQAAPQQNKASSKDMFAEHLSKSIIKHSLDKSKSVLPNIDKKPVSKEHMLVLGEESQLTLGETPKFLDFSDNSPQYCVPECKDSVGFGFSLEALPPCSMMTSQKSDLKGVMKDKVVTRHNLTNTAFEPLSFGQESSFRPSQTLSSAVLTCVDSLHVEDKQKIRDRNVIPDTPPSTPLVPSQTSSEWDIKKLTKQLKGELAKEFAPATPPSTPHNSSVGSLSENEQTTIEKEEFMLKLMRSLSEEVESSEGEEHPEMDVKSEHSGKKGQFADALATHIISLATEVAASHLDHEITQEFKVQNSHLTVPSQRSMLPALSHSDESIQTCSFASDMAAGVIAEAEKVANTRSCMLFGHERTICHVEGDRGKAEEKLDVEDIAHPREVETCVLSLPSCMPGLTYKYPSCESVTDEYAGHIIQVLKQEGGNSELIMDQYASRLAYRSVKSGVREAAKTVKVKCSLKLFPMHTSHVKTNKELLFSSKEHHQEVDKKRQRKKYGSHPCKYQTCDRTQDPCRNELSELYRFSASLASSITRDVKKQLTAPKVDLPKSSTDCCLFEKSECVDNRENVTGPEFSKSCQPLQNHGLCQNTSSLSGYSCGESAHTVEQYARKVVGDTLELSLGPAVFLNSETTTSPDRITYAEKLSPLINEACRYCDLKESHGCIRNSAQLFSKQGPCASAKPSSHSKLSSIRQKSRIFHLDVPQIHLNLDKRAVLAEKIVAEAIEKAERELSNTSLAADSGIGQDGISFAESLTTEIMTTAMTNAGHAVSSSKEVEDFQSTESLGSQQMNLSVGEDSTGSWSNLSFEDDHQDESSSFHHLSESSNGNSSSWSSLGLEGDLYENNLSFPTSDSDGPDDRESEQEDGAEGLQPSGKTLLIVNIDVEPGAVDPQLRVILQWLIPRRRKLENFIFSTLQRRSLSYFQSSYRREDGKWAMSCRL", "length": 1129 }, "evidence": [ { "id": "HGNC:369", "url": "https://alliancegenome.org/gene/HGNC:369#orthology", "database": "AGR" }, { "id": "MGI:2684060", "url": "https://alliancegenome.org/gene/MGI:2684060#orthology", "database": "AGR" }, { "id": "RGD:2079", "url": "https://alliancegenome.org/gene/RGD:2079#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090804-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090804-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UKA4-1", "protein_name": "A-kinase anchor protein 11", "gene_name": "AKAP11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATFRNNHMKTKASVRKSFSEDVFQSVKSLLQSQKELCSVTAEDCLQQDEHANLTEVTFLGFNEETDAAHIQDLAAVSLELPDILNSLHFCSLNENEIICMKNINKPLDISSDPLNQSHPSGMLCVMRVSPTSPRLRIDFIFSLLSKYATGIRYTLDTFLHQKHQLETTDEDDDDTNQSVSSIEDDFVTAFEHLEEEETSKPYNDGMNITVLRSQCDAASQTVTGHHLETHDLKILISSGQQKSLAKPSTSSVNVLGHKELPSVKTSVTTSISEPWTQRSFYRSSNASDKDSDLQKTFFSSSPAYSSESECSSPSPVIFLDEEGYQKSLKAKLELPKIPVMKDDIEDSDSEVSEFFDSFDQFDELEQTLETCLFNKDPVIGKSSQRKGHKHGKSCMNPQKFKFDRPALPANVRKPTPRKPESPYGNLCDAPDSPRPVKASREDSGLFSPIRSSAFSPLGGCTPAECFCQTDIGGDRIHENHDSVYYTYEDYAKSISCEVLGSVLRTHHTNTLSNINSIKHGENKTVTFKHGNLDQKNKSKNKSLMIKDSIQKFAADLVEKSFGSAFKDLQKGVSSCTNALYHLAIKLTSSVLQMAFDELRRQRAFSLKERAISGLANFLVSEALSNALKDLQYVKKQIFTNTVARFAADLAEELVFEGIMEVCQFSYPQTPASPQCGSFDFEDKVVKLYAKDLSESVIQEAFIELSQVDVTFTTKAAVSVSTDNIKYVSAESVVPSTQAVTFSPSFHNQAIMVTKPVQEYKKEYTVQQALFCTSGIVTSIPVPLAGSALLPYHISSTACQAKAHLSSDDSNSNGDSAQVHIATKNREEKAACLRNICLPSEHNPGNQNDFKPTNDDIEMQSSSKLPNDPAIISNFSAAVVHTIVNETLESMTSLEVTKMVDERTDYLTKSLKEKTPPFSHCDQAVLQCSEASSNKDMFADRLSKSIIKHSIDKSKSVIPNIDKNAVYKESLPVSGEESQLTPEKSPKFPDSQNQLTHCSLSAAKDCVPECKVSMVHGSSLETLPSCPAVTGQKSDLKESAKDQPLKKHNLNSTSLEALSFGQENPFPHSHTFSSTALTCVDGLHVEDKQKVRDRNVIPDTPPSTPLVPSRASSEWDIKKLTKKLKGELAKEFAPATPPSTPHNSSVGSLSENEQNTIEKEEFMLKLMRSLSEEVESSESGELPEVDVKSEHSGKKVQFAEALATHILSLATEMAASHLDNKIIQEPKVKNPCLNVQSQRSVSPTFLNPSDENLKTLCNFAGDLAAEVITEAEKIAKVRNCMLFKQKKNSCYADGDEDYKVEEKLDIEAVVHPREVDPFILSLPPSSCMSGLMYKYPSCESVTDEYAGHLIQILKQEGGNSELIMDQYANRLAYRSVKSGLQEAAKTTKVQCNSRMFPVPSSQVKTNKELLMFSNKEHHQEADKKRQSKRNEGYFCKNQTCERTLDPYRNEVSQLYSFSTSLVHSITKDAKEELTASLVGLPKSLTDSCLFEKSGYEEDNECHVTPELPKSLQPSSQNHRFYHSTGSLNGYGCGDNVVQAVEQYAKKVVDDTLELTLGSTVFRVSETTKSADRVTYAEKLSPLTGQACRYCDLKELHNCTGNSSQHFFRQGSLASSKPASNPKFSSRYQKSRIFHLSVPQIHVNLDKKAVLAEKIVAEAIEKAERELSSTSLAADSGIGQEGASFAESLATETMTAAVTNVGHAVSSSKEIEDFQSTESVSSQQMNLSIGDDSTGSWSNLSFEDEHQDESSSFHHLSESNGNSSSWSSLGLEGDLYEDNLSFPTSDSDGPDDKDEEHEDEVEGLGQDGKTLLITNIDMEPCTVDPQLRIILQWLIASEAEVAELYFHDSANKEFMLLSKQLQEKGWKVGDLLQAVLQYYEVMEKASSEERCKSLFDWLLENA", "length": 1901 }, "evidence": [ { "id": "HGNC:369", "url": "https://alliancegenome.org/gene/HGNC:369#orthology", "database": "AGR" }, { "id": "MGI:2684060", "url": "https://alliancegenome.org/gene/MGI:2684060#orthology", "database": "AGR" }, { "id": "RGD:2079", "url": "https://alliancegenome.org/gene/RGD:2079#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090804-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090804-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8J5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor protein serine/threonine kinase signaling pathway", "id": "GO:0007178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007178", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8J5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8J5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase A binding", "id": "GO:0051018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051018", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8J5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8J5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1360, "end_pos": 1362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1598, "end_pos": 1600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1622, "end_pos": 1624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1654, "end_pos": 1656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 503, "end_pos": 505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 839, "end_pos": 841, "annotation": "n_glycosylation_sequon" }, { "start_pos": 853, "end_pos": 855, "annotation": "n_glycosylation_sequon" }, { "start_pos": 866, "end_pos": 868, "annotation": "n_glycosylation_sequon" }, { "start_pos": 901, "end_pos": 903, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1041 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1360, "end_pos": 1362 }, { "start_pos": 1598, "end_pos": 1600 }, { "start_pos": 1622, "end_pos": 1624 }, { "start_pos": 1654, "end_pos": 1656 }, { "start_pos": 178, "end_pos": 180 }, { "start_pos": 503, "end_pos": 505 }, { "start_pos": 633, "end_pos": 635 }, { "start_pos": 839, "end_pos": 841 }, { "start_pos": 853, "end_pos": 855 }, { "start_pos": 866, "end_pos": 868 }, { "start_pos": 901, "end_pos": 903 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z7U9-1", "uniprot_ac": "A0A8M6Z7U9", "uniprot_id": "A0A8M6Z7U9_DANRE", "mass": { "chemical_mass": 123756.0, "monoisotopic_mass": 123756.0 }, "refseq": { "ac": "XP_017212531", "name": "tripartite motif-containing protein 66 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212531" }, "gene_names": [ { "name": "trim66", "type": "recommended", "evidence": [ { "id": "A0A8M6Z7U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9" } ] }, { "name": "trim66", "type": "synonym", "evidence": [ { "id": "XP_017212531", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212531" } ] } ], "protein_names": [ { "name": "Tripartite motif-containing protein 66 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z7U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9/entry#names_and_taxonomy" } ] }, { "name": "tripartite motif-containing protein 66 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017212531", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212531" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017212531.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017212531", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212531" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "trim66", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040724-145", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-145", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z7U9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z7U9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05502", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05502", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19794", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19794", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19811", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19811", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "566660", "url": "https://www.ncbi.nlm.nih.gov/gene/566660", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003649", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003649", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566660", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566660", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PQDFQWP", "url": "https://omabrowser.org/oma/group/PQDFQWP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YZF5", "url": "https://www.orthodb.org/?gene=A0A8M6YZF5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z7U9", "url": "https://www.orthodb.org/?gene=A0A8M6Z7U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45915", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45915", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45915:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45915:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25287", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25287", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017212531", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212531", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YZF5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YZF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZF5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1R2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1R2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z7U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z7U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TXL6", "url": "https://www.uniprot.org/uniprotkb/A0AB32TXL6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TXL6-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TXL6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G4G7", "url": "https://www.uniprot.org/uniprotkb/A0AC58G4G7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G4G7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G4G7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040724-145", "url": "https://zfin.org/ZDB-GENE-040724-145", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MCQQILFFWNAVDFQCTFIHLPLQCCSECSEPRMAQSLCTFCNKWLCFQCTDLHQHERSSSQPSDLQHQPRDPPSPSEIGAACCGHAVVMCPLHKQEPLELLCETCDLMACSICHLSAHKDHRLVHVGKALQDQRWLLQNLMARVEEKRSAVESTAKQIQGRLHGIKITQRKAENQIKMAKMIMMNELNKRANLLIEQLESISSDFKQRLEDQLQGAIELCSQLEHVQNFITWATAHHRRNPLLFSKELIALQMQQLLEPLMLSEAWSPLKIKFNWDASFWTKQMSTLGQLVVEGGSRSYSDVVGHSSILRPQPVPCIAMPPLCHAVREPGCAYQTFCQPSLCCLHCRPAQTVPLEKFPAQCAQATRRSSPPSLHSCWDTETSVPVHPPGAQPMQQSTSHPGSDLVQHGSSSSQPRHPVGSNIELLPADSGQTVMDEKSSTTGQKASRRGQTSAPEASTGPEASADAELPQIHKQAQMQTTAETSCQPMVELQSIAARIGDDDDRRSSELEMFALVQGQVGDGRSCPGLKRASRSQSSADAPRGPRKRLCKDRSIKDAHGLATATGDQGCTTQQQTCAQLHASEMYPSSHVASSLTTYKSEPENVYAYAYENKRLKTRKKHRNSRDDPHTSDKESSDGSKVPVVCLQRLKILVSRHPPQNHQSTDPSSQSGLKPEETVLKVLEREAASQGTLDKESVQAEDNMSPTETQLSPQHLHSCESSGSLEDSQPPVQEFCNINQESDALSVSKDAVLQPDAEEIHSDDSPSDLISAPGSDFQTESTREADVESELPQESELQVESESDVISEQLPESVLSEQEMESDPDSTAEVNLNLEPECEWETEQPVSPQSSGFENVPEPVVEHQPSEESPEIENEDFCAVCLIGGDLLCCDRCPKVFHLSCHVPPLHSFPVGDWICTLCRDVEQPEVEYDCENVQMSTGMMPYGLSACDQRKCEKLTLLILSNILSAPFHEPVSPLARHYYQIIKKPMDLSVIRNRLGSNSHTHYCSPQEFVADVLLMFKNCAKFNYPDSEVAQAGHSLQSFFISKLREVFPDLSCPVQEEEEEDSDTEDYEELERAMMTGFPWPERKEQSHRKRKRRLSLNRRRNHF", "length": 1107, "header": "tr|A0A8M6Z7U9-1|A0A8M6Z7U9_DANRE Isoform 1 of Tripartite motif-containing protein 66 isoform X1 OS=Danio rerio OX=7955 GN=trim66 PE=4 SV=2 CANONICAL=A0A8M6Z7U9-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YZF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9/entry#A0A8M6YZF5-1", "sequence": { "sequence": "MCQQILFFWNAVDFQCTFIHLPLQCCSECSEPRMAQSLCTFCNKWLCFQCTDLHQHERSSSQPSDLQHQPRDPPSPSEIGAACCGHAVVMCPLHKQEPLELLCETCDLMACSICHLSAHKDHRLVHVGKALQDQRWLLQNLMARVEEKRSAVESTAKQIQGRLHGIKITQRKAENQIKMAKMIMMNELNKRANLLIEQLESISSDFKQRLEDQLQGAIELCSQLEHVQNFITWATAHHRRNPLLFSKELIALQMQQLLEPLMLSEAWSPLKIKFNWDASFWTKQMSTLGQLVVEGGSRSYSDVVGHSSILRPQPVPCIAMPPLCHAVREPGCAYQTFCQPSLCCLHCRPAQTVPLEKFPAQCAQATRRSSPPSLHSCWDTETSVPVHPPGAQPMQQSTSHPGSDLVQHGSSSSQPRHPVGSNIELLPADSGQTVMDEKSSTTGQKASRRGQTSAPEASTGPEASADAELPQIHKQAQMQTTAETSCQPMVELQSIAARIGDDDDRRSSELEMFALVQGQVGDGRSCPGLKRASRSQSSADAPRGPRKRLCKDRSIKDAHGLATATGDQGCTTQQTCAQLHASEMYPSSHVASSLTTYKSEPENVYAYAYENKRLKTRKKHRNSRDDPHTSDKESSDGSKVPVVCLQRLKILVSRHPPQNHQSTDPSSQSGLKPEETVLKVLEREAASQGTLDKESVQAEDNMSPTETQLSPQHLHSCESSGSLEDSQPPVQEFCNINQESDALSVSKDAVLQPDAEEIHSDDSPSDLISAPGSDFQTESTREADVESELPQESELQVESESDVISEQLPESVLSEQEMESDPDSTAEVNLNLEPECEWETEQPVSPQSSGFENVPEPVVEHQPSEESPEIENEDFCAVCLIGGDLLCCDRCPKVFHLSCHVPPLHSFPVGDWICTLCRDVEQPEVEYDCENVQMSTGMMPYGLSACDQRKCEKLTLLILSNILSAPFHEPVSPLARHYYQIIKKPMDLSVIRNRLGSNSHTHYCSPQEFVADVLLMFKNCAKFNYPDSEVAQAGHSLQSFFISKLREVFPDLSCPVQEEEEEDSDTEDYEELERAMMTGFPWPERKEQSHRKRKRRLSLNRRRNHF", "length": 1106, "header": "tr|A0A8M6YZF5-1|A0A8M6Z7U9_DANRE Computationally mapped isoform of Tripartite motif-containing protein 66 isoform X1 OS=Danio rerio OX=7955 GN=trim66 PE=4 SV=2 CANONICAL=A0A8M6Z7U9-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z1R2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9/entry#A0A8M6Z1R2-1", "sequence": { "sequence": "MEKCCSECSEPRMAQSLCTFCNKWLCFQCTDLHQHERSSSQPSDLQHQPRDPPSPSEIGAACCGHAVVMCPLHKQEPLELLCETCDLMACSICHLSAHKDHRLVHVGKALQDQRWLLQNLMARVEEKRSAVESTAKQIQGRLHGIKITQRKAENQIKMAKMIMMNELNKRANLLIEQLESISSDFKQRLEDQLQGAIELCSQLEHVQNFITWATAHHRRNPLLFSKELIALQMQQLLEPLMLSEAWSPLKIKFNWDASFWTKQMSTLGQLVVEGGSRSYSDVVGHSSILRPQPVPCIAMPPLCHAVREPGCAYQTFCQPSLCCLHCRPAQTVPLEKFPAQCAQATRRSSPPSLHSCWDTETSVPVHPPGAQPMQQSTSHPGSDLVQHGSSSSQPRHPVGSNIELLPADSGQTVMDEKSSTTGQKASRRGQTSAPEASTGPEASADAELPQIHKQAQMQTTAETSCQPMVELQSIAARIGDDDDRRSSELEMFALVQGQVGDGRSCPGLKRASRSQSSADAPRGPRKRLCKDRSIKDAHGLATATGDQGCTTQQQTCAQLHASEMYPSSHVASSLTTYKSEPENVYAYAYENKRLKTRKKHRNSRDDPHTSDKESSDGSKVPVVCLQRLKILVSRHPPQNHQSTDPSSQSGLKPEETVLKVLEREAASQGTLDKESVQAEDNMSPTETQLSPQHLHSCESSGSLEDSQPPVQEFCNINQESDALSVSKDAVLQPDAEEIHSDDSPSDLISAPGSDFQTESTREADVESELPQESELQVESESDVISEQLPESVLSEQEMESDPDSTAEVNLNLEPECEWETEQPVSPQSSGFENVPEPVVEHQPSEESPEIENEDFCAVCLIGGDLLCCDRCPKVFHLSCHVPPLHSFPVGDWICTLCRDVEQPEVEYDCENVQMSTGMMPYGLSACDQRKCEKLTLLILSNILSAPFHEPVSPLARHYYQIIKKPMDLSVIRNRLGSNSHTHYCSPQEFVADVLLMFKNCAKFNYPDSEVAQAGHSLQSFFISKLREVFPDLSCPVQEEEEEDSDTEDYEELERAMMTGFPWPERKEQSHRKRKRRLSLNRRRNHF", "length": 1086, "header": "tr|A0A8M6Z1R2-1|A0A8M6Z1R2_DANRE Computationally mapped isoform of Tripartite motif-containing protein 66 isoform X3 OS=Danio rerio OX=7955 GN=trim66 PE=4 SV=1 CANONICAL=A0A8M6Z7U9-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z7U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9/entry#A0A8M6Z7U9-1", "sequence": { "sequence": "MCQQILFFWNAVDFQCTFIHLPLQCCSECSEPRMAQSLCTFCNKWLCFQCTDLHQHERSSSQPSDLQHQPRDPPSPSEIGAACCGHAVVMCPLHKQEPLELLCETCDLMACSICHLSAHKDHRLVHVGKALQDQRWLLQNLMARVEEKRSAVESTAKQIQGRLHGIKITQRKAENQIKMAKMIMMNELNKRANLLIEQLESISSDFKQRLEDQLQGAIELCSQLEHVQNFITWATAHHRRNPLLFSKELIALQMQQLLEPLMLSEAWSPLKIKFNWDASFWTKQMSTLGQLVVEGGSRSYSDVVGHSSILRPQPVPCIAMPPLCHAVREPGCAYQTFCQPSLCCLHCRPAQTVPLEKFPAQCAQATRRSSPPSLHSCWDTETSVPVHPPGAQPMQQSTSHPGSDLVQHGSSSSQPRHPVGSNIELLPADSGQTVMDEKSSTTGQKASRRGQTSAPEASTGPEASADAELPQIHKQAQMQTTAETSCQPMVELQSIAARIGDDDDRRSSELEMFALVQGQVGDGRSCPGLKRASRSQSSADAPRGPRKRLCKDRSIKDAHGLATATGDQGCTTQQQTCAQLHASEMYPSSHVASSLTTYKSEPENVYAYAYENKRLKTRKKHRNSRDDPHTSDKESSDGSKVPVVCLQRLKILVSRHPPQNHQSTDPSSQSGLKPEETVLKVLEREAASQGTLDKESVQAEDNMSPTETQLSPQHLHSCESSGSLEDSQPPVQEFCNINQESDALSVSKDAVLQPDAEEIHSDDSPSDLISAPGSDFQTESTREADVESELPQESELQVESESDVISEQLPESVLSEQEMESDPDSTAEVNLNLEPECEWETEQPVSPQSSGFENVPEPVVEHQPSEESPEIENEDFCAVCLIGGDLLCCDRCPKVFHLSCHVPPLHSFPVGDWICTLCRDVEQPEVEYDCENVQMSTGMMPYGLSACDQRKCEKLTLLILSNILSAPFHEPVSPLARHYYQIIKKPMDLSVIRNRLGSNSHTHYCSPQEFVADVLLMFKNCAKFNYPDSEVAQAGHSLQSFFISKLREVFPDLSCPVQEEEEEDSDTEDYEELERAMMTGFPWPERKEQSHRKRKRRLSLNRRRNHF", "length": 1107, "header": "tr|A0A8M6Z7U9-1|A0A8M6Z7U9_DANRE Isoform 1 of Tripartite motif-containing protein 66 isoform X1 OS=Danio rerio OX=7955 GN=trim66 PE=4 SV=2 CANONICAL=A0A8M6Z7U9-1" }, "locus": {} }, { "isoform_ac": "A0AB32TXL6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9/entry#A0AB32TXL6-1", "sequence": { "sequence": "MAQSLCTFCNKWLCFQCTDLHQHERSSSQPSDLQHQPRDPPSPSEIGAACCGHAVVMCPLHKQEPLELLCETCDLMACSICHLSAHKDHRLVHVGKALQDQRWLLQNLMARVEEKRSAVESTAKQIQGRLHGIKITQRKAENQIKMAKMIMMNELNKRANLLIEQLESISSDFKQRLEDQLQGAIELCSQLEHVQNFITWATAHHRRNPLLFSKELIALQMQQLLEPLMLSEAWSPLKIKFNWDASFWTKQMSTLGQLVVEGGSRSYSDVVGHSSILRPQPVPCIAMPPLCHAVREPGCAYQTFCQPSLCCLHCRPAQTVPLEKFPAQCAQATRRSSPPSLHSCWDTETSVPVHPPGAQPMQQSTSHPGSDLVQHGSSSSQPRHPVGSNIELLPADSGQTVMDEKSSTTGQKASRRGQTSAPEASTGPEASADAELPQIHKQAQMQTTAETSCQPMVELQSIAARIGDDDDRRSSELEMFALVQGQVGDGRSCPGLKRASRSQSSADAPRGPRKRLCKDRSIKDAHGLATATGDQGCTTQQQTCAQLHASEMYPSSHVASSLTTYKSEPENVYAYAYENKRLKTRKKHRNSRDDPHTSDKESSDGSKVPVVCLQRLKILVSRHPPQNHQSTDPSSQSGLKPEETVLKVLEREAASQGTLDKESVQAEDNMSPTETQLSPQHLHSCESSGSLEDSQPPVQEFCNINQESDALSVSKDAVLQPDAEEIHSDDSPSDLISAPGSDFQTESTREADVESELPQESELQVESESDVISEQLPESVLSEQEMESDPDSTAEVNLNLEPECEWETEQPVSPQSSGFENVPEPVVEHQPSEESPEIENEDFCAVCLIGGDLLCCDRCPKVFHLSCHVPPLHSFPVGDWICTLCRDVEQPEVEYDCENVQMSTGMMPYGLSACDQRKCEKLTLLILSNILSAPFHEPVSPLARHYYQIIKKPMDLSVIRNRLGSNSHTHYCSPQEFVADVLLMFKNCAKFNYPDSEVAQAGHSLQSFFISKLREVFPDLSCPVQEEEEEDSDTEDYEELERAMMTGFPWPERKEQSHRKRKRRLSLNRRRNHF", "length": 1074, "header": "tr|A0AB32TXL6-1|A0A8M6Z7U9_DANRE Computationally mapped isoform of Tripartite motif-containing protein 66 isoform X1 OS=Danio rerio OX=7955 GN=trim66 PE=4 SV=2 CANONICAL=A0A8M6Z7U9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4G7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9/entry#A0AC58G4G7-1", "sequence": { "sequence": "MEKCCSECSEPRMAQSLCTFCNKWLCFQCTDLHQHERSSSQPSDLQHQPRDPPSPSEIGAACCGHAVVMCPLHKQEPLELLCETCDLMACSICHLSAHKDHRLVHVGKALQDQRWLLQNLMARVEEKRSAVESTAKQIQGRLHGIKITQRKAENQIKMAKMIMMNELNKRANLLIEQLESISSDFKQRLEDQLQGAIELCSQLEHVQNFITWATAHHRRNPLLFSKELIALQMQQLLEPLMLSEAWSPLKIKFNWDASFWTKQMSTLGQLVVEGGSRSYSDVVGHSSILRPQPVPCIAMPPLCHAVREPGCAYQTFCQPSLCCLHCRPAQTVPLEKFPAQCAQATRRSSPPSLHSCWDTETSVPVHPPGAQPMQQSTSHPGSDLVQHGSSSSQPRHPVGSNIELLPADSGQTVMDEKSSTTGQKASRRGQTSAPEASTGPEASADAELPQIHKQAQMQTTAETSCQPMVELQSIAARIGDDDDRRSSELEMFALVQGQVGDGRSCPGLKRASRSQSSADAPRGPRKRLCKDRSIKDAHGLATATGDQGCTTQQTCAQLHASEMYPSSHVASSLTTYKSEPENVYAYAYENKRLKTRKKHRNSRDDPHTSDKESSDGSKVPVVCLQRLKILVSRHPPQNHQSTDPSSQSGLKPEETVLKVLEREAASQGTLDKESVQAEDNMSPTETQLSPQHLHSCESSGSLEDSQPPVQEFCNINQESDALSVSKDAVLQPDAEEIHSDDSPSDLISAPGSDFQTESTREADVESELPQESELQVESESDVISEQLPESVLSEQEMESDPDSTAEVNLNLEPECEWETEQPVSPQSSGFENVPEPVVEHQPSEESPEIENEDFCAVCLIGGDLLCCDRCPKVFHLSCHVPPLHSFPVGDWICTLCRDVEQPEVEYDCENVQMSTGMMPYGLSACDQRKCEKLTLLILSNILSAPFHEPVSPLARHYYQIIKKPMDLSVIRNRLGSNSHTHYCSPQEFVADVLLMFKNCAKFNYPDSEVAQAGHSLQSFFISKLREVFPDLSCPVQEEEEEDSDTEDYEELERAMMTGFPWPERKEQSHRKRKRRLSLNRRRNHF", "length": 1085, "header": "tr|A0AC58G4G7-1|A0AC58G4G7_DANRE Computationally mapped isoform of Tripartite motif-containing protein 66 isoform X4 OS=Danio rerio OX=7955 GN=trim66 PE=4 SV=1 CANONICAL=A0A8M6Z7U9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:566660", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566660", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1M6Z0-1", "protein_name": "Tripartite motif-containing protein 66", "gene_name": "Trim66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPGLGLSFPRQRLCSTDECVEAVAPTCSMCRGDLRAEGSRLLPCQHLLCKACFQGCLQELVHVPRAHWTAPGELISCPGCQRIYLTRDVTEHIFLQCFSPGKPTMARSCSECKEKRAAHILCTYCNRWLCSSCTEEHRHVPAPGGPLFARAQKGSSGVNGGSGDFALYCPLHTHEVLKLFCETCDVLTCHSCLMVEHKEHRCRHVEEVLQNQRMLLESVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGGQLTRADAAPAAYGNLQGQSSFYQSHQAPMAQQEALSHPSHKFQSPALCSSSVCCSHCSPVSPSLKGQVPPPSIHPVHSFRQPSEMVPHQLGSLQCPTLLPREKEPACSPHPPKLLQPWLEPQPPAEQEGTSQRPGQQLVSQPVCIVPPQDVQPGAHAQPTIQTPSIQVQLGHHQKLKLSHFQQQPQQQPPPPPPPPLPAPQHAPPPLPPSQHLASSQHESPPGPACSQNVDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEDTLQVTEEPPASEGPKPALPVDKNTATSLSQTSGEETPHSAPSVDSSSQHSSPNVVRKHATSVSIMGFSNTVEMELSSTRLARTIEPQIHRVSSLTAAPTHTIPSLLSGPSQTVSSLMSVSNHAMPSLTASHLQPVPNLVRGAFQSTPNPRGDSSQAITSLASTHSQAGPSLVSGHTQAVPSLATCPLQGMPPVSDLHVEPRSVSSPGSGPTAESLGPRDGAESSLGNALCKLESEDGTRFTDSVGQGPTAPSLDDPKDLAIPSELEEPINLSVKKPLLAPVISTAAAPQQSRNLKEYENFEQGALELDTKENSNSSAIGSEPKIPYVRLERLKICAAPSGEMPVFKLKPQKNSQDGSFLLVIECGAESSSMSIKVSQSSLSDANQGPGLGGRKVTVTSLTGQRPLEVDGTSDEHRLIPRTLGAKKCIPAPIENEDFCAVCINGGELLCCDRCPKVYHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENARYSHPGVRALPGLSMYDQKKCEKLVLSLCCNSLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPDKCFAQPQQEDSDSEDVSGESGCSTPQGFPWPPYMQEGIQPKRRRRHMENEKTKRVSFRLTNSISQTPQIHKK", "length": 1354 }, "evidence": [ { "id": "RGD:1595847", "url": "https://alliancegenome.org/gene/RGD:1595847#orthology", "database": "AGR" }, { "id": "MGI:2152406", "url": "https://alliancegenome.org/gene/MGI:2152406#orthology", "database": "AGR" }, { "id": "HGNC:29005", "url": "https://alliancegenome.org/gene/HGNC:29005#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-145", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-145#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15016-1", "protein_name": "Tripartite motif-containing protein 66", "gene_name": "TRIM66", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFMGLPLAGQKHCPKSGQMEAMVMTCSLCHQDLPGMGSHLLSCQHLLRKDCFQGLIQELGQIAKAHETVADELISCPGCERVYLTRDVTEHFFLHCVPTEQPKMARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHSPVPGGPFFPRAQKGSPGVNGGPGDFTLYCPLHTQEVLKLFCETCDMLTCHSCLVVEHKEHRCRHVEEVLQNQRMLLEGVTTQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKTSVPFLFSKELIVFQMQRLLETSCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGGQMSRADAPAYGGLQGSSPFYQSHQSPVAQQEALSHPSHKFQSPAVCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQPVCIVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQLPPPPPPLPHPPPPLPPPPQQPHPPLPPSQHLASSQHESPPGPACSQNMDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETLQATDEPPASQGSKPALPLDKNTAAALPQASGEETPLSVPPVDSTIQHSSPNVVRKHSTSLSIMGFSNTLEMELSSTRLERPLEPQIQSVSNLTAGAPQAVPSLLSAPPKMVSSLTSVQNQAMPSLTTSHLQTVPSLVHSTFQSMPNLISDSPQAMASLASDHPQAGPSLMSGHTQAVPSLATCPLQSIPPVSDMQPETGSSSSSGRTSGSLCPRDGADPSLENALCKMESEDSTRFTDLLGQGPIVPGLDAPKDLAIPSELEEPINLSVKKPPLAPVVSTSTALQQYQNPKECENFEQGALELDAKENQSIRAFNSEHKIPYVRLERLKICAASSGEMPVFKLKPQKNDQDGSFLLIIECGTESSSMSIKVSQDRLSEATQAPGLEGRKVTVTSLAGQRPPEVEGTSPEEHRLIPRTPGAKKGPPAPIENEDFCAVCLNGGELLCCDRCPKVFHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENACYNQPGMRASPGLSMYDQKKCEKLVLSLCCNNLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPEKRFAQPRQEDSDSEEVSSESGCSTPQGFPWPPYMQEGIQPKRRRRHMENERAKRMSFRLANSISQV", "length": 1351 }, "evidence": [ { "id": "RGD:1595847", "url": "https://alliancegenome.org/gene/RGD:1595847#orthology", "database": "AGR" }, { "id": "MGI:2152406", "url": "https://alliancegenome.org/gene/MGI:2152406#orthology", "database": "AGR" }, { "id": "HGNC:29005", "url": "https://alliancegenome.org/gene/HGNC:29005#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-145", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-145#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q924W6-1", "protein_name": "Tripartite motif-containing protein 66", "gene_name": "Trim66", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSPGLPVSIPSQPHCSTDERVEALAPTCSMCGRDLQAEGSRLLPCQHLLCKDCYQGFMQELGHATRAYPGKLISCPGCQRVYLTRDVTEHIFLQCFSPVKPTMARNCSECKEKRAAHILCTYCNRWLCSSCTEEHRHVPAPGGPLFARAQKGSSGVNGGSGDFALYCPLHTQEVLKLFCETCDVLTCHSCLMVEHKEHRCRHVEEVLQNQRMLLESVTSQVAHKKSSLQTSAKQIEDRIFEVKHQHRKVENQIKMAKMVLMNELNKQANGLIEELEGITNERKRKLEQQLQSIMVLNRQFEHVQNFINWAVCSKSSVPFLFSKELIVFQMQRLLETRCNTDPGSPWSIRFTWEPNFWTKQLASLGCITTEGGQLTRADAAAASYGSLQGQPSFYQSHQAPMAQQEALSHPSHKFQSPALCSSSVCCSHCSPVSPSLKGQVPPPSIHPAHSFRQPSEMVPHQLGSLQCSTLLPREKELACSPHPPKLMQPWLEPQPPAEQESTSQRPGPQLVSQPVCIVPPQDVQPGAHAQPTIQTPSIQVQLGHHQKLKLSHFQQQPQQQPPPPPPPPPPPQHAPPPLPPSQHLASSQHESPPGPACSQNVDIMHHKFELEEMQKDLELLLQAQQPSLQLSQTKSPQHLQQTIVGQINYIVRQPAPVQSQSQEETLQVTEEPPAPEGPKPALPVDKNTAAPLPQTSGEETPHSVPPVDGTSQHSSPNVVRKHATSVSIMGFSNTVEMELSSTRLARTIEPQIHRVSSLTAAPTHTIPSLLSGPPQTVSSLMSVSNHAMPSLTASHLQPVPNLVRGTFQSTSNLRGDSSQAITGLASNHSQAGPSLMSGHTQAAPSLATCPLQGMPPVSDVHVEPRSVSSPGSGPAAESLGTRDGAESSLGNALCKMESEDCTRFSDSVGQGPTASSLDGPKDLAIPSELEEPINLSVKKPFLAPVINTSTALQQYRNPKEYENFEQGALELDTKENSDIRAISSEPKIPYVRLERLKICAASSGEMPVFKLKPQKNSQDGNFLLVIECGTESSSMSIKVSQNSLPDASQGPGLGGRKVTVTSLTGQQPQEVESTSEEHRLIPRAPGAKKNTPAPIENEDFCAVCINGGELLCCDRCPKVYHLSCHVPALLSFPGGEWVCTLCRSLTQPEMEYDCENARYGHPGVRVLPGLSMYDQKKCEKLVLSLCCNSLSLPFHEPVSPLARHYYQIIKRPMDLSIIRRKLQKKDPAHYTTPEEVVSDVRLMFWNCAKFNYPDSEVAEAGRCLEVFFEGWLKEIYPDKCFAQPQQEDSDSEDVSGESGCSTPQGFPWPPYMQEGIQPKRRRRHMENEKTKRVSFRLANSISQV", "length": 1344 }, "evidence": [ { "id": "RGD:1595847", "url": "https://alliancegenome.org/gene/RGD:1595847#orthology", "database": "AGR" }, { "id": "MGI:2152406", "url": "https://alliancegenome.org/gene/MGI:2152406#orthology", "database": "AGR" }, { "id": "HGNC:29005", "url": "https://alliancegenome.org/gene/HGNC:29005#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-145", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-145#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9" } ], "pmid": "" }, { "name": "chromatin", "id": "GO:0000785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000785", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z7U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 127, "start_aa": "His", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z7U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 960, "end_pos": 1032, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z7U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U9" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 874, "end_pos": 921, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 702, "end_pos": 704 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z6P0-1", "uniprot_ac": "A0A8M6Z6P0", "uniprot_id": "A0A8M6Z6P0_DANRE", "mass": { "chemical_mass": 16995.0, "monoisotopic_mass": 16995.0 }, "refseq": { "ac": "XP_017211916", "name": "centromere protein R isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211916" }, "gene_names": [ { "name": "itgb3bp", "type": "recommended", "evidence": [ { "id": "A0A8M6Z6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0" } ] }, { "name": "itgb3bp", "type": "synonym", "evidence": [ { "id": "XP_017211916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211916" } ] }, { "name": "si:dkey-148h10.5", "type": "synonym", "evidence": [ { "id": "XP_017211916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211916" }, { "id": "A0A8M6Z6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0" } ] } ], "protein_names": [ { "name": "Centromere protein R isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0/entry#names_and_taxonomy" } ] }, { "name": "centromere protein R isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017211916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211916" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211916", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211916" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "itgb3bp", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131127-260", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-260", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z6P0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z6P0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000097493", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000097493", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "107988039", "url": "https://www.ncbi.nlm.nih.gov/gene/107988039", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:107988039", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:107988039", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RHENLCA", "url": "https://omabrowser.org/oma/group/RHENLCA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z6P0", "url": "https://www.orthodb.org/?gene=A0A8M6Z6P0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "X1WGM0", "url": "https://www.orthodb.org/?gene=X1WGM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15581", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15581", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15581:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15581:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017211916", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211916", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TXP0", "url": "https://www.uniprot.org/uniprotkb/A0AB32TXP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TXP0-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TXP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X1WGM0", "url": "https://www.uniprot.org/uniprotkb/X1WGM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X1WGM0-1", "url": "https://www.uniprot.org/uniprotkb/X1WGM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131127-260", "url": "https://zfin.org/ZDB-GENE-131127-260", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPAKRALDLEDKENSPAKRHVANRNYSPMAGMTKPKAGNSKAVGKKTNPPETKEPLTDAERIVFLRSKLQKSLKDLMKYRQQLETLVPVEGSSELRSLLLMSPADLQTELKRHEILSAKIASSPHRADTNKGPFQGLKQTGSSSEYLKAILSR", "length": 153, "header": "tr|A0A8M6Z6P0-1|A0A8M6Z6P0_DANRE Isoform 1 of Centromere protein R isoform X1 OS=Danio rerio OX=7955 GN=itgb3bp PE=4 SV=1 CANONICAL=A0A8M6Z6P0-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z6P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0/entry#A0A8M6Z6P0-1", "sequence": { "sequence": "MPAKRALDLEDKENSPAKRHVANRNYSPMAGMTKPKAGNSKAVGKKTNPPETKEPLTDAERIVFLRSKLQKSLKDLMKYRQQLETLVPVEGSSELRSLLLMSPADLQTELKRHEILSAKIASSPHRADTNKGPFQGLKQTGSSSEYLKAILSR", "length": 153, "header": "tr|A0A8M6Z6P0-1|A0A8M6Z6P0_DANRE Isoform 1 of Centromere protein R isoform X1 OS=Danio rerio OX=7955 GN=itgb3bp PE=4 SV=1 CANONICAL=A0A8M6Z6P0-1" }, "locus": {} }, { "isoform_ac": "A0AB32TXP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0/entry#A0AB32TXP0-1", "sequence": { "sequence": "MPAKRALDLEDKENSPAKRHVANRNYSPMAGMTKPKAGNSKAVGKKTNPPETKEPLTDAERIVFLRSKLQKSLKDLMKYRQQLETLVPVEGSSELRSLLLMSPADLQTELKRHEILWLKQTGSSSEYLKAILSR", "length": 134, "header": "tr|A0AB32TXP0-1|A0A8M6Z6P0_DANRE Computationally mapped isoform of Centromere protein R isoform X1 OS=Danio rerio OX=7955 GN=itgb3bp PE=4 SV=1 CANONICAL=A0A8M6Z6P0-1" }, "locus": {} }, { "isoform_ac": "X1WGM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0/entry#X1WGM0-1", "sequence": { "sequence": "MPAKRALDLEDKENSPAKRHVANRNYSPMAGMTKPKGNSKAVGKKTNPPETKEPLTDAERIVFLRSKLQKSLKDLMKYRQQLETLVPVEGSSELRSLLLMSPADLQTELKRHEILSAKIASSPHRADTNKGPFQGLKQTGSSSEYLKAILSR", "length": 152, "header": "tr|X1WGM0-1|A0A8M6Z6P0_DANRE Computationally mapped isoform of Centromere protein R isoform X1 OS=Danio rerio OX=7955 GN=itgb3bp PE=4 SV=2 CANONICAL=A0A8M6Z6P0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "X1WGM0", "url": "https://www.uniprot.org/uniprotkb/X1WGM0" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:107988039", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:107988039", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q13352-1", "protein_name": "Centromere protein R", "gene_name": "ITGB3BP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPVKRSLKLDGLLEENSFDPSKITRKKSVITYSPTTGTCQMSLFASPTSSEEQKHRNGLSNEKRKKLNHPSLTESKESTTKDNDEFMMLLSKVEKLSEEIMEIMQNLSSIQALEGSRELENLIGISCASHFLKREMQKTKELMTKVNKQKLFEKSTGLPHKASRHLDSYEFLKAILN", "length": 177 }, "evidence": [ { "id": "RGD:1310044", "url": "https://alliancegenome.org/gene/RGD:1310044#orthology", "database": "AGR" }, { "id": "MGI:1914983", "url": "https://alliancegenome.org/gene/MGI:1914983#orthology", "database": "AGR" }, { "id": "HGNC:6157", "url": "https://alliancegenome.org/gene/HGNC:6157#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131127-260", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-260#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5U1Z7-1", "protein_name": "Centromere protein R", "gene_name": "Itgb3bp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVKRSLKLDDQFEENSFGPSKIMRKKSITAFSPTTGTYQLSPFSSPRTPKEQEHRDGPSNGTRKWSVLSSPARQDSTVKGSDGFMMLLSKIERSSEKTMEIMKNLSSLQALEGNRQLEDLLGVSLVPCSLKSEAKKTKELMTKVMKQKLFEKKNSRIPPKEHHPNSFEFLKAILN", "length": 176 }, "evidence": [ { "id": "RGD:1310044", "url": "https://alliancegenome.org/gene/RGD:1310044#orthology", "database": "AGR" }, { "id": "MGI:1914983", "url": "https://alliancegenome.org/gene/MGI:1914983#orthology", "database": "AGR" }, { "id": "HGNC:6157", "url": "https://alliancegenome.org/gene/HGNC:6157#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131127-260", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-260#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9CQ82-1", "protein_name": "Centromere protein R", "gene_name": "Itgb3bp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPVKRSLKLDDQFEKNSFSPSKIVRKKSITAYSPTTGTYQLSPFSSPATPKEQEHRNGPSNETRKRSNLSSPVRQESTVKDRDGFMVLLSKIEISSEKTMEIMKNLSSIQALEGNRQLEDLIGVSLVPCSLKSEARKTKELMTKVIKQKLFEKKKSRITPKDHHLDSFEFLKAILN", "length": 176 }, "evidence": [ { "id": "RGD:1310044", "url": "https://alliancegenome.org/gene/RGD:1310044#orthology", "database": "AGR" }, { "id": "MGI:1914983", "url": "https://alliancegenome.org/gene/MGI:1914983#orthology", "database": "AGR" }, { "id": "HGNC:6157", "url": "https://alliancegenome.org/gene/HGNC:6157#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131127-260", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-260#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0" } ], "pmid": "" }, { "name": "CENP-A containing chromatin assembly", "id": "GO:0034080", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034080", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6P0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6P0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 25, "end_pos": 27 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M6Z3K5-1", "uniprot_ac": "A0A8M6Z3K5", "uniprot_id": "A0A8M6Z3K5_DANRE", "mass": { "chemical_mass": 111779.0, "monoisotopic_mass": 111779.0 }, "refseq": { "ac": "XP_017214016", "name": "multimerin-2 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214016" }, "gene_names": [ { "name": "mmrn2b", "type": "recommended", "evidence": [ { "id": "A0A8M6Z3K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3K5" } ] }, { "name": "mmrn2b", "type": "synonym", "evidence": [ { "id": "XP_017214016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214016" } ] } ], "protein_names": [ { "name": "Multimerin-2 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A8M6Z3K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3K5/entry#names_and_taxonomy" } ] }, { "name": "multimerin-2 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_017214016", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214016" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017214016.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214016" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3K5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3K5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mmrn2b", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3K5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080415-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080415-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z3K5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z3K5", "database": "AlphaFoldDB", "categories": [] }, { "id": "566255", "url": "https://www.ncbi.nlm.nih.gov/gene/566255", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050392", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050392", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566255", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566255", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z3K5", "url": "https://www.orthodb.org/?gene=A0A8M6Z3K5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15427:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15427:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07546", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07546", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017214016", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214016", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3K5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3K5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U5H9", "url": "https://www.uniprot.org/uniprotkb/A0AB32U5H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U5H9-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32U5H9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GXY8", "url": "https://www.uniprot.org/uniprotkb/A0AC58GXY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GXY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GXY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080415-2", "url": "https://zfin.org/ZDB-GENE-080415-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAQTLPLLLLAVLNSLSCHSEVRARDPDVEEEEAVGNLGKPTGTIETAHLMEQSHQGIPMPPAGTAQDSAALRETVHPPTRRGNWCAYVNHRVVTTAVLCATETQTVKSMNPCPGGAPDCQVLMYKQSLRPAYKQKHTTLSSIHWNCCPGYSGHNCLEKDKPSKDEKLASKSEVNDNDNSGGGTFSGGKTETDLMEDANWADKPLQETPIHDSSPNKRPDWDREGISASKPLPIFDSSILLTMHQLMSTMMSQIQPVLESFNQTLEHLSSEVNTLSRDLQQLRMEQKDNRFISRGEGHSGPFEDRLEYNHLQISQIKTQLEAQKDQMERTFQTQKELLKHNLTKIKEELDEQISQSQESQINLQSLTDLVVEVRSGQKKLEGALQRERDKFVNLMEGQPTQASGAWEAITRIDEKAQSNSVQLSSLSEALKDSSRVVQDLKRDQVKLGNSLEEVKQRTQVHFAETGLELEATHIKVVNSLGELTANVSAHEGQLREIELDLVNIYNLLQRNDSVTAEQTCSCKVINSSLVRLEKEVDNVTQLARQNSLALEEADLERNEATEMEDLQHGLLNMKESLAFEQGRSRSLQDSILQLQDSLLDSKLEIQGLREQDGEQSAEIQGLSAAFSSLLNDAVRHSEVLEVLLGEEVLEFTHWSQSRQKDLSLPDLLQTIQMMQQKIETHDRSLTSLRRKHPDGDEMNSDDPVPYSEKPGMKQQMKGTEGYQTSSADPSNAEDDVDYSVSDFWSLGKEVEQLANRISMLEERCGNSTEPPGGSVLELQEEIASLRQSQEDHLRLFGKLFSKTEELASSTRSLNLDEVWRMVRRKEGKRRRGDQKQADHMRNEERNTSGRSKRYSQTEQAWFPQSPVVFVTNLDDIKKPNAELTSKNILLNYGGMFKPTSGVFQAPETGLYLFLVTLDFERGLSLAVLNRSGVPIATFKQEHGEKMGPVSRASLLELRRGETVTLELTHGSLRKAQPGDNTLSGLLLFITEHKDML", "length": 996, "header": "tr|A0A8M6Z3K5-1|A0A8M6Z3K5_DANRE Isoform 1 of Multimerin-2 isoform X3 OS=Danio rerio OX=7955 GN=mmrn2b PE=4 SV=3 CANONICAL=A0A8M6Z3K5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z3K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3K5/entry#A0A8M6Z3K5-1", "sequence": { "sequence": "MAQTLPLLLLAVLNSLSCHSEVRARDPDVEEEEAVGNLGKPTGTIETAHLMEQSHQGIPMPPAGTAQDSAALRETVHPPTRRGNWCAYVNHRVVTTAVLCATETQTVKSMNPCPGGAPDCQVLMYKQSLRPAYKQKHTTLSSIHWNCCPGYSGHNCLEKDKPSKDEKLASKSEVNDNDNSGGGTFSGGKTETDLMEDANWADKPLQETPIHDSSPNKRPDWDREGISASKPLPIFDSSILLTMHQLMSTMMSQIQPVLESFNQTLEHLSSEVNTLSRDLQQLRMEQKDNRFISRGEGHSGPFEDRLEYNHLQISQIKTQLEAQKDQMERTFQTQKELLKHNLTKIKEELDEQISQSQESQINLQSLTDLVVEVRSGQKKLEGALQRERDKFVNLMEGQPTQASGAWEAITRIDEKAQSNSVQLSSLSEALKDSSRVVQDLKRDQVKLGNSLEEVKQRTQVHFAETGLELEATHIKVVNSLGELTANVSAHEGQLREIELDLVNIYNLLQRNDSVTAEQTCSCKVINSSLVRLEKEVDNVTQLARQNSLALEEADLERNEATEMEDLQHGLLNMKESLAFEQGRSRSLQDSILQLQDSLLDSKLEIQGLREQDGEQSAEIQGLSAAFSSLLNDAVRHSEVLEVLLGEEVLEFTHWSQSRQKDLSLPDLLQTIQMMQQKIETHDRSLTSLRRKHPDGDEMNSDDPVPYSEKPGMKQQMKGTEGYQTSSADPSNAEDDVDYSVSDFWSLGKEVEQLANRISMLEERCGNSTEPPGGSVLELQEEIASLRQSQEDHLRLFGKLFSKTEELASSTRSLNLDEVWRMVRRKEGKRRRGDQKQADHMRNEERNTSGRSKRYSQTEQAWFPQSPVVFVTNLDDIKKPNAELTSKNILLNYGGMFKPTSGVFQAPETGLYLFLVTLDFERGLSLAVLNRSGVPIATFKQEHGEKMGPVSRASLLELRRGETVTLELTHGSLRKAQPGDNTLSGLLLFITEHKDML", "length": 996, "header": "tr|A0A8M6Z3K5-1|A0A8M6Z3K5_DANRE Isoform 1 of Multimerin-2 isoform X3 OS=Danio rerio OX=7955 GN=mmrn2b PE=4 SV=3 CANONICAL=A0A8M6Z3K5-1" }, "locus": {} }, { "isoform_ac": "A0AB32U5H9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3K5/entry#A0AB32U5H9-1", "sequence": { "sequence": "MAQTLPLLLLAVLNSLSCHSEVRARDPDVEEEEAVGNLGKPTGTIETAHLMEQSHQGIPMPPAGTAQDSAALRETVHPPTRRGNWCAYVNHRVVTTAVLCATETQTVKSMNPCPGGAPDCQVLMYKQSLRPAYKQKHTTLSSIHWNCCPGYSGHNCLEKDKPSKDEKLASKSEVNDNDNSGGKTETDLMEDANWADKPLQETPIHDSSPNKRPDWDREGISASKPLPIFDSSILLTMHQLMSTMMSQIQPVLESFNQTLEHLSSEVNTLSRDLQQLRMEQKDNRFISRGEGHSGPFEDRLEYNHLQISQIKTQLEAQKDQMERTFQTQKELLKHNLTKIKEELDEQISQSQESQINLQSLTDLVVEVRSGQKKLEGALQRERDKFVNLMEGQPTQASGAWEAITRIDEKAQSNSVQLSSLSEALKDSSRVVQDLKRDQVKLGNSLEEVKQRTQVHFAETGLELEATHIKVVNSLGELTANVSAHEGQLREIELDLVNIYNLLQRNDSVTAEQTCSCKVINSSLVRLEKEVDNVTQLARQNSLALEEADLERNEATEMEDLQHGLLNMKESLAFEQGRSRSLQDSILQLQDSLLDSKLEIQGLREQDGEQSAEIQGLSAAFSSLLNDAVRHSEVLEVLLGEEVLEFTHWSQSRQKDLSLPDLLQTIQMMQQKIETHDRSLTSLRRKHPDGDEMNSDDPVPYSEKPGMKQQMKGTEGYQTSSADPSNAEDDVDYSVSDFWSLGKEVEQLANRISMLEERCGNSTEPPGGSVLELQEEIASLRQSQEDHLRLFGKLFSKTEELASSTRSLNLDEVWRMVRRKEGKRRRGDQKQADHMRNEERNTSGRSKRYSQTEQAWFPQSPVVFVTNLDDIKKPNAELTSKNILLNYGGMFKPTSGVFQAPETGLYLFLVTLDFERGLSLAVLNRSGVPIATFKQEHGEKMGPVSRASLLELRRGETVTLELTHGSLRKAQPGDNTLSGLLLFITEHKDML", "length": 990, "header": "tr|A0AB32U5H9-1|A0A8M6Z3K5_DANRE Computationally mapped isoform of Multimerin-2 isoform X3 OS=Danio rerio OX=7955 GN=mmrn2b PE=4 SV=2 CANONICAL=A0A8M6Z3K5-1" }, "locus": {} }, { "isoform_ac": "A0AC58GXY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3K5/entry#A0AC58GXY8-1", "sequence": { "sequence": "MAQTLPLLLLAVLNSLSCHSEVRARDPDVEEEEAVGNLGKPTGTIETAHLMEQSHQGIPMPPAGTAQDSAALRETVHPPTRRGNWCAYVNHRVVTTAVLCATETQTVKSMNPCPGGAPDCQVLMYKQSLRPAYKQKHTTLSSIHWNCCPGYSGHNCLEKDKPSKDEKLASKSEVNDNDNSGDREGISASKPLPIFDSSILLTMHQLMSTMMSQIQPVLESFNQTLEHLSSEVNTLSRDLQQLRMEQKDNRFISRGEGHSGPFEDRLEYNHLQISQIKTQLEAQKDQMERTFQTQKELLKHNLTKIKEELDEQISQSQESQINLQSLTDLVVEVRSGQKKLEGALQRERDKFVNLMEGQPTQASGAWEAITRIDEKAQSNSVQLSSLSEALKDSSRVVQDLKRDQVKLGNSLEEVKQRTQVHFAETGLELEATHIKVVNSLGELTANVSAHEGQLREIELDLVNIYNLLQRNDSVTAEQTCSCKVINSSLVRLEKEVDNVTQLARQNSLALEEADLERNEATEMEDLQHGLLNMKESLAFEQGRSRSLQDSILQLQDSLLDSKLEIQGLREQDGEQSAEIQGLSAAFSSLLNDAVRHSEVLEVLLGEEVLEFTHWSQSRQKDLSLPDLLQTIQMMQQKIETHDRSLTSLRRKHPDGDEMNSDDPVPYSEKPGMKQQMKGTEGYQTSSADPSNAEDDVDYSVSDFWSLGKEVEQLANRISMLEERCGNSTEPPGGSVLELQEEIASLRQSQEDHLRLFGKLFSKTEELASSTRSLNLDEVWRMVRRKEGKRRRGDQKQADHMRNEERNTSGRSKRYSQTEQAWFPQSPVVFVTNLDDIKKPNAELTSKNILLNYGGMFKPTSGVFQAPETGLYLFLVTLDFERGLSLAVLNRSGVPIATFKQEHGEKMGPVSRASLLELRRGETVTLELTHGSLRKAQPGDNTLSGLLLFITEHKDML", "length": 956, "header": "tr|A0AC58GXY8-1|A0AC58GXY8_DANRE Computationally mapped isoform of Multimerin-2 isoform X2 OS=Danio rerio OX=7955 GN=mmrn2b PE=4 SV=1 CANONICAL=A0A8M6Z3K5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:566255", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566255", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GHU7-1", "protein_name": "Multimerin-2", "gene_name": "Mmrn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLAGWAGPGHFLPLLSLCFLFFLTFCLKTTSPANSGVTCKAEPQHRQLSLPLTMILTLLLGLAGYLSWGLLGSWAQDPGSRFSNPNRLSVPEGWRIGADDDTSRDPSQRTTKWTPLPERGLFHPAIFFPSRLLESQLPRRQGQGIVATGIFWNWCPYQKSRLVTFVAACKTEKFLVHSQQPCPQGAPDCQRVKVMYRVAQKPVYQVQQKVLMSVDWRCCPGFQGPDCQDHHPTANPEPTEASGKLQETWDSLDGFEPGHPVTEFNEIKAPQEHLLQNLQNDAQPVEDGFAGPWEAPSSNLTAAMTEANLTEFESLGRTSKHLLQPHIHAFLEAHFSPIWKSFNESLQSLFQAIRNLSLDVEANHRAIKMIQEGTVARADFRELGAKFEAKVQQNSQRLGQLWQDVEDQLHAQRRSVHHALSEVQAEVSTKLKQLVKAQELPGANGSLAVASAARPEPESLQARLGQLQRNLSALHMVTNQREEELRGTLKDMDSVLRQHTDEIKELYSESDETFDQISKVERQVEELLVNHTGLRELRVILMEKSLIMEENKEEMERQLLDLNLTLQHLQAAHADLIKYVKDCNCRRVYSDMDVIPEGRRDAMHTLEETQVSPDEQHQLDGSLQALQSTVDAMSSALDAYRGEGERARAERARMRSQLRALDHAVEALKTAANGTRKEIRLLHGSFAALLEDALRHQAVLAALFGEEMVDEMSEEPPRPLPLNYEQIRLALQDAASGLQEQAVGWEDLATRVEALEKAAGGFVEQHPRSAEGLEPSHDFGREEDTRALGDLEQEIQRLSSDVKQMGQCCEASWALNGSLEDLHSALSDTQHSLRQHQQLFRGLFHNFQGLLASNTSLDLDKLQAMLSKKDKKQQKGPGESRKRDKKQVVMSADAKGLGLWEAGSPVAFYASSSEEATALQMVKFNATSVNVGSGYFPEHGYFRAPKRGIYLFAVSVTFGPGPGMGQLVFEGHRRVPVYSAEQRGGSTATTFAMAELQKGERVWFELIQGSVTKGSRPGTAFGGFLMFKT", "length": 1030 }, "evidence": [ { "id": "RGD:1311461", "url": "https://alliancegenome.org/gene/RGD:1311461#orthology", "database": "AGR" }, { "id": "MGI:2385618", "url": "https://alliancegenome.org/gene/MGI:2385618#orthology", "database": "AGR" }, { "id": "HGNC:19888", "url": "https://alliancegenome.org/gene/HGNC:19888#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080415-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080415-2#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1NTG9-1", "protein_name": "Multimerin-2a precursor", "gene_name": "mmrn2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVVLKLSVLLQGLLLVARCEVRARDPEVEDEDELKDMSDGGGWDPRVPLIGFGAARHGEVINRKRPDVYGALHHPVGHHGHHDHGHQDVPEGTVDPSSATETTGSFQRTGNWCAFVHKQAVTVAVACGTEKYTIKSQSPCPNGTPDCQVIMYKLSTRPVYRQKQRINTALQWRCCPGHSGANCDETVTDGHISQSETEDPSQAGRPHPGGPEETDRRFNNLTPENREQNDYQTFGGLMYEAQQPDVENQTGPSIEDYEHIPPAGQENHNKHHFERRDPYAVSEGVPYPETPYLHDRLLLALKEAVVSQLQPVLENFNLTLERLSQEVQGLQRDMAHLRHDQGQGRITEPQEIGGEDHNSQEAVEAELRESLLKLEEVKAEFHNHRNEVEARLHAQQTMLHYNLTNFKTDMDVKIKRNQKMLQVNLQSLNTSMSEVRQEQERLDEELQKIWPEKRTDPTESQSHVSTAVWEAITRLDNKVVNNTVRLSALIEEQEQVTENIRGLHNGWKDLNDKIVQTGRNSQVQFMETGLEVEAAKVRVLDRIDELSSNISVIQSALQDVETDVDNIYIDFYKNISSASGECDCIALGATVTHLEQTVADVMKTVNENILAQEMMANRHNRAWVPSVEDLKLGLLNVQNSLAFQQEKSRTLQHNVTQALASLLGSQQDIEMLQKQDRAKVEKIKQLEGTFNTLLQDATRHSDVLEILLGEEVLEFTKWSQQDKRRFSIPQLDERMKDMQKQINGHSLSLASMLNAATPQVTAADEPSLLADWASTGTKRKREDARFDLSEELPEYSDDDFWTLEKTVKELEAHIKRLEDHRCPTCCNCTKTAASSGVEVKLQTELDTLRKDLETHVGVFKSIFSNTEGLAASEVSVDLDKLSTLMKRKEVKHQKKQKKADKRLFQTGEKVDLRSKRDASLESAVLRQLPDSPVMFLASSNEGANGSGTVLFESVALNHGQLYSPKTGAFRAPTSGVYLFVVTLDFGSGLSLAQLKRGEEVVASMRQNPRKLGAPATRVIILEMEQGEELRLELVQGTIERNNPQDNTFAGLLMLQTT", "length": 1057 }, "evidence": [ { "id": "RGD:1311461", "url": "https://alliancegenome.org/gene/RGD:1311461#orthology", "database": "AGR" }, { "id": "MGI:2385618", "url": "https://alliancegenome.org/gene/MGI:2385618#orthology", "database": "AGR" }, { "id": "HGNC:19888", "url": "https://alliancegenome.org/gene/HGNC:19888#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6H6E2-1", "protein_name": "Multimerin-2", "gene_name": "Mmrn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPTLLLGFGVYLSWGLLGSWAQDPGTKFSHLNRPGMPEGWRLGAEDTSRDPIRRNWCPYQKSRLVTFVAACKTEKFLVHSQQPCPQGAPDCQGVRVMYRVAQKPVYQVQQKVLISVDWRCCPGFQGPDCQDHNPTANPEPTEPSGKLQETWDSMDGFELGHPVPEFNEIKVPQEQQENLLQNLQNDAQSVEDGFPGSWEAPPSNLTDEMTEANLTEFEFPGRTSEHLLQPHIDAFLKAHFSPIWKNFNDSLHSLSQAIRNLSLDVEANHQAIKMIQEGTVARADFQELGAKFEAKVQQNSQRLGQLWQDVEDQLHAQRRSVHHALSDVQAEVSTKLKQLVKAQELPGANGSLVMASAAAAARPEPESLQARLGQLQRNLSALHMVTSQREEELQSTLKNMDSVLKQHAEEIKELYSESDETFDQISKVERQVEELLVNHTGLRELRVILMEKSLIMEENKEEIERQLLELNLTLQHLHAGHADLIKYVKDCNCQRVNSDVDVAPEGHRDVMHTLEETQVSLDEQHQLDGSSLQALQSTVDAMSSAMDAYRGEGERARAERARIRSQLRALDHAVEALKTAANGTRKEIRLLHGSFTALLEDALRHQAVLAALFGEEMIDEMSEEAPRPLPLDYEQIRLALQDAASGLQEQAIGWEDLATRVEALEKAAGGFVEQHPQLAEGLEPSHDSGREEEAMTLAELEQEIRRLSSDVKQIGQCCEASWAASLNSSLEDLHSMLLDTQHGLRQHRQLFHNLFQNFQGLVASNISLDLGKLQAMLSKKDKKQPRGPGESRKRDKKQVVMSTDAHAKGLELWETGSPVAFYAGSSEGATALQMVKFNTTSINVGSSYFPEHGYFRAPKRGVYLFAVSITFGPGPGMGQLVFEGHHRVPVYSTEQRGGSTATTFAMVELQKGERAWFELIQGSATKGSQPGTAFGGFLMFKT", "length": 943 }, "evidence": [ { "id": "RGD:1311461", "url": "https://alliancegenome.org/gene/RGD:1311461#orthology", "database": "AGR" }, { "id": "MGI:2385618", "url": "https://alliancegenome.org/gene/MGI:2385618#orthology", "database": "AGR" }, { "id": "HGNC:19888", "url": "https://alliancegenome.org/gene/HGNC:19888#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080415-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080415-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H8L6-1", "protein_name": "Multimerin-2", "gene_name": "MMRN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MILSLLFSLGGPLGWGLLGAWAQASSTSLSDLQSSRTPGVWKAEAEDTGKDPVGRNWCPYPMSKLVTLLALCKTEKFLIHSQQPCPQGAPDCQKVKVMYRMAHKPVYQVKQKVLTSLAWRCCPGYTGPNCEHHDSMAIPEPADPGDSHQEPQDGPVSFKPGHLAAVINEVEVQQEQQEHLLGDLQNDVHRVADSLPGLWKALPGNLTAAVMEANQTGHEFPDRSLEQVLLPHVDTFLQVHFSPIWRSFNQSLHSLTQAIRNLSLDVEANRQAISRVQDSAVARADFQELGAKFEAKVQENTQRVGQLRQDVEDRLHAQHFTLHRSISELQADVDTKLKRLHKAQEAPGTNGSLVLATPGAGARPEPDSLQARLGQLQRNLSELHMTTARREEELQYTLEDMRATLTRHVDEIKELYSESDETFDQISKVERQVEELQVNHTALRELRVILMEKSLIMEENKEEVERQLLELNLTLQHLQGGHADLIKYVKDCNCQKLYLDLDVIREGQRDATRALEETQVSLDERRQLDGSSLQALQNAVDAVSLAVDAHKAEGERARAATSRLRSQVQALDDEVGALKAAAAEARHEVRQLHSAFAALLEDALRHEAVLAALFGEEVLEEMSEQTPGPLPLSYEQIRVALQDAASGLQEQALGWDELAARVTALEQASEPPRPAEHLEPSHDAGREEAATTALAGLARELQSLSNDVKNVGRCCEAEAGAGAASLNASLHGLHNALFATQRSLEQHQRLFHSLFGNFQGLMEANVSLDLGKLQTMLSRKGKKQQKDLEAPRKRDKKEAEPLVDIRVTGPVPGALGAALWEAGSPVAFYASFSEGTAALQTVKFNTTYINIGSSYFPEHGYFRAPERGVYLFAVSVEFGPGPGTGQLVFGGHHRTPVCTTGQGSGSTATVFAMAELQKGERVWFELTQGSITKRSLSGTAFGGFLMFKT", "length": 949 }, "evidence": [ { "id": "RGD:1311461", "url": "https://alliancegenome.org/gene/RGD:1311461#orthology", "database": "AGR" }, { "id": "MGI:2385618", "url": "https://alliancegenome.org/gene/MGI:2385618#orthology", "database": "AGR" }, { "id": "HGNC:19888", "url": "https://alliancegenome.org/gene/HGNC:19888#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080415-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080415-2#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 341, "end_pos": 343, "annotation": "n_glycosylation_sequon" }, { "start_pos": 486, "end_pos": 488, "annotation": "n_glycosylation_sequon" }, { "start_pos": 511, "end_pos": 513, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 846, "end_pos": 848, "annotation": "n_glycosylation_sequon" }, { "start_pos": 929, "end_pos": 931, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z3K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3K5" }, { "id": "PS50871", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50871" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C1q", "eco_id": "ECO_0000259", "start_pos": 862, "end_pos": 993, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z3K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3K5" }, { "id": "PS51041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EMI", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 158, "start_aa": "Arg", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 262, "end_pos": 264 }, { "start_pos": 341, "end_pos": 343 }, { "start_pos": 486, "end_pos": 488 }, { "start_pos": 511, "end_pos": 513 }, { "start_pos": 526, "end_pos": 528 }, { "start_pos": 538, "end_pos": 540 }, { "start_pos": 766, "end_pos": 768 }, { "start_pos": 846, "end_pos": 848 }, { "start_pos": 929, "end_pos": 931 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PH02-1", "uniprot_ac": "A0A8M9PH02", "uniprot_id": "A0A8M9PH02_DANRE", "mass": { "chemical_mass": 31374.0, "monoisotopic_mass": 31374.0 }, "refseq": { "ac": "XP_021323964", "name": "solute carrier family 66 member 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323964" }, "gene_names": [ { "name": "slc66a2", "type": "recommended", "evidence": [ { "id": "A0A8M9PH02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02" } ] }, { "name": "slc66a2", "type": "synonym", "evidence": [ { "id": "XP_021323964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323964" } ] } ], "protein_names": [ { "name": "Solute carrier family 66 member 2", "type": "recommended", "evidence": [ { "id": "A0A8M9PH02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02/entry#names_and_taxonomy" } ] }, { "name": "PQ-loop repeat-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8M9PH02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 66 member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323964" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323964" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PH02", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "slc66a2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-170203-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-170203-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PH02", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PH02", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000112922", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000112922", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101883969", "url": "https://www.ncbi.nlm.nih.gov/gene/101883969", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006603", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006603", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052241", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052241", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101883969", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101883969", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FKMWFFF", "url": "https://omabrowser.org/oma/group/FKMWFFF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PH02", "url": "https://www.orthodb.org/?gene=A0A8M9PH02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14856", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14856", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14856:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14856:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323964", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A2R8QPC7", "url": "https://www.uniprot.org/uniprotkb/A0A2R8QPC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2R8QPC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A2R8QPC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PH02", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PH02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I086", "url": "https://www.uniprot.org/uniprotkb/A0AC58I086", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I086-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I086-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I096", "url": "https://www.uniprot.org/uniprotkb/A0AC58I096", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I096-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I096-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-170203-1", "url": "https://zfin.org/ZDB-GENE-170203-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDEVIMDQVLYVVHQVVSWVASVAIIFGGIVPYIPQYRDIRRTQNAEGFSTYVCLVLLVANILRILFRFGRYFETPLLWQSIIMIVTMLIMLNLCTSVRMATELNTKRRSFTATDSKDEEIKVPKRLFLDFDWNYFWSWSRFVDYLQCVLAFTVLAAYVTYLLLDSVLFVESLGFLAVFTEAMLGTPQLYCNYQNKSTEGMSIKMVLMWTSGDTFKTGYFLLTQAPMQFWICGLLQVCVDFTILFQVYYYSHYPQKPISHTTHTTSAKAL", "length": 270, "header": "tr|A0A8M9PH02-1|A0A8M9PH02_DANRE Isoform 1 of Solute carrier family 66 member 2 OS=Danio rerio OX=7955 GN=slc66a2 PE=4 SV=1 CANONICAL=A0A8M9PH02-1" }, "isoforms": [ { "isoform_ac": "A0A2R8QPC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02/entry#A0A2R8QPC7-1", "sequence": { "sequence": "MDEVIMDQVLYVVHQVVSWVASVAIIFGGIVPYIPQYRDIRRTQNAEGFSTYVCLVLLVANILRILFRFGRYFETPLLWQSIIMIVTMLIMLNLCTSVRMATELNTKRRSFTDFDWNYFWSWSRFVDYLQCVLAFTVLAAYVTYLLLDSVLFVESLGFLAVFTEAMLGTPQLYCNYQNKSTEGMSIKMVLMWTSGDTFKTGYFLLTQAPMQFWICGLLQVCVDFTILFQVYYYSHYPQKPISHTTHTTSAKAL", "length": 253, "header": "tr|A0A2R8QPC7-1|A0A8M9PH02_DANRE Computationally mapped isoform of Solute carrier family 66 member 2 OS=Danio rerio OX=7955 GN=slc66a2 PE=4 SV=1 CANONICAL=A0A8M9PH02-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PH02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02/entry#A0A8M9PH02-1", "sequence": { "sequence": "MDEVIMDQVLYVVHQVVSWVASVAIIFGGIVPYIPQYRDIRRTQNAEGFSTYVCLVLLVANILRILFRFGRYFETPLLWQSIIMIVTMLIMLNLCTSVRMATELNTKRRSFTATDSKDEEIKVPKRLFLDFDWNYFWSWSRFVDYLQCVLAFTVLAAYVTYLLLDSVLFVESLGFLAVFTEAMLGTPQLYCNYQNKSTEGMSIKMVLMWTSGDTFKTGYFLLTQAPMQFWICGLLQVCVDFTILFQVYYYSHYPQKPISHTTHTTSAKAL", "length": 270, "header": "tr|A0A8M9PH02-1|A0A8M9PH02_DANRE Isoform 1 of Solute carrier family 66 member 2 OS=Danio rerio OX=7955 GN=slc66a2 PE=4 SV=1 CANONICAL=A0A8M9PH02-1" }, "locus": {} }, { "isoform_ac": "A0AC58I086-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02/entry#A0AC58I086-1", "sequence": { "sequence": "MDEVIMDQVLYVVHQVVSWVASVAIIFGGIVPYIPQYRDIRRTQNAEGFSTYVCLVLLVANILRILFRFGRYFETPLLWQSIIMIVTMLIMLNLCTSVRMATELNTKRRSFTATDSKDEEIKVPKRLFLDFDWNYFWSWSRFVDYLQCVLAFTVLAAYVTYLLLDSVLFVESLGFLAVFTEAMLGTPQLYCNYQNKSTEGMSIKMVLMWTSGDTFKTGYFLLTQAPMQFWICGLLQDQDWLKCSVYF", "length": 247, "header": "tr|A0AC58I086-1|A0AC58I086_DANRE Computationally mapped isoform of Solute carrier family 66 member 2 OS=Danio rerio OX=7955 GN=slc66a2 PE=4 SV=1 CANONICAL=A0A8M9PH02-1" }, "locus": {} }, { "isoform_ac": "A0AC58I096-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02/entry#A0AC58I096-1", "sequence": { "sequence": "MDEVIMDQVLYVVHQVVSWVASVAIIFGGIVPYIPQYRDIRRTQNAEGFSTYVCLVLLVANILRILFRFGRYFETPLLWQSIIMIVTMLIMLNLCTSVRMATELNTKRRSFTDFDWNYFWSWSRFVDYLQCVLAFTVLAAYVTYLLLDSVLFVESLGFLAVFTEAMLGTPQLYCNYQNKSTEGMSIKMVLMWTSGDTFKTGYFLLTQAPMQFWICGLLQDQDWLKCSVYF", "length": 230, "header": "tr|A0AC58I096-1|A0AC58I096_DANRE Computationally mapped isoform of Solute carrier family 66 member 2 OS=Danio rerio OX=7955 GN=slc66a2 PE=4 SV=1 CANONICAL=A0A8M9PH02-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101883969", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101883969", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BEV0-1", "protein_name": "Solute carrier family 66 member 2", "gene_name": "SLC66A2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEAEGLDWLLVPLQQLVSWGAAAAMVFGGVVPYIPQYRDIRRTQNAEGFSTYVCLVLLVANILRILFWFGRHFESPLLWQSVVMILTMLLMLRLCTEVRVANELNVKRRFFAAADNKDEEIRVAPRRSYLDLDPHHFWRWSSFGDYVQCVLAFTGVAGYVTYLSIDSALFVETLGFLAVLTEAMLGVPQLYRNHRLQSTEGMSIKMVLMWTSGDTFKTAYFLLNGAPLQFSVCGLLQVLVDLAILGQAYAFTRHPLKPAPHATHPASAKAL", "length": 271 }, "evidence": [ { "id": "A0A8M9PH02", "url": "https://omabrowser.org/oma/group/A0A8M9PH02/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M9PEZ6-1", "protein_name": "Solute carrier family 66 member 2", "gene_name": "BcDNA:SD10385", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDWIINDEMGLTVGHVVGWAAASAMVIGGVIPYVPQYIEIKKTQDAEGFSLYVCLALLVANSLRILFWFSSRYELPLLVQSVVMNVTMFLMIHLCVKVKRVNANNREHALRGDELHLPKVMTDTDTGASISTEAGGSVLKRVRSRHYLNDLDFKYFWNWTDFQSYLDFMLVVWAVGAAITYLMLSVLWFMESMGFVAVFTEAMLGAPQFLRNFKNKSTYGMSIHMVIMWTLGDMFKTGYFIVRKAPSQFWICGTLQVSLDIAILSQVWFYRKNSKPRDLRRGDXQFAPEEQPQHIHHHDIHTSHSEEHQLSLPVTVSSSGDDHLLTARADDEHFKVLDFGQCHDNRAFQYHNNNKMLPRPGGSGKSKDDSSMAAALEVVIVHSPASKEPRLIGAQEESGRCRRKQNNATQTKLEGGSCCCVITTHHHHCHCNHHRHHHHHHHCHYRSTKRRALLHQKRSHHHQKHMPIKQANHKQMLPSNNNNNNKSSLDSSDEAMHHQAIAIEIDAATMSEDGDENNSSTATSNFPYKVASEGVKPIIMAPLREQHRHRRGSLNSNTTIETDELSRDEDDDDDVRMGSHHLPEDETQLTQPAVTNSSSSSTKRGNPASAPARNECVRIKRKRFIAEAGQDYCSSCSSSCSCSSLDEDLEAHHEMTVAAECHQCIPGSRRASLCSCQNSSCCCGSCSQEDDEEEEADDEDDETTGQRESFCTAADHTITPSQEGEDMHSSTLTPLSTHRSSFMDQDHGDHTMRSDIGGGNITDADASSLSQSAEYFSLSSTAGGGTSFPTKEEDKMDKLEIKETKDLREKEVEQPSCKHWNRNPHGKHKRGSSPVDNSLXRSVSLVAWPAIDVNALLQQTIRKSAVLQETPVRRKTTAKRGSGTTGSNDSSTATLTASVVTVAKFPGTGLVSTVTSLNGCGTTYSYTTTTAAPLNLAASSKKNTKYSPVPNSEAYQCDPLQQSSTEIIL", "length": 969 }, "evidence": [ { "id": "A0A8M9PH02", "url": "https://omabrowser.org/oma/group/A0A8M9PH02/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q0VCC1-1", "protein_name": "Solute carrier family 66 member 2", "gene_name": "SLC66A2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEAEGLGWLLVPLHQLVSWGAAGAMVFGGVVPYIPQYRDIRRTQNAEGFSTYVCLVLLVANILRILFWFGRHFESPLLWQSVVMILTMLLMLKLCTEVRVANELNLKRRVFSDFDPHHFWHWSSFADYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDTFKTAYFLLNGAPLQFSVCGLLQVLVDLAILGQAYVFTRYPLKPAPHAAHPASAKAL", "length": 253 }, "evidence": [ { "id": "A0A8M9PH02", "url": "https://omabrowser.org/oma/group/A0A8M9PH02/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54C20-1", "protein_name": "Solute carrier family 66 member 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MASIITSGLFIFAPVIGYVSQYRDIQRTSNSDGFSTRVCLILLLSNILRCYFWIGKQFDITLLYQSIVMIIAQLLMLHLCISIKSRESVTNSKSRRSNKQFNFQTNTTKTTITNIIPNNNNNNNNNNNNKTSNITIDNNDNNSNENIINNNNDNDNNDNEIIITTMKSSNNNTKNHHIFLNPGYFQNFWEWDNFGAYTIFLGVYSAIFLLLTTVYLYSPSYFEYLGTLSLTIESILGLPQLIQNYKKRSTKGLSLVLISSWFIGDLFKTLYFYYKDQPSQFIFCGTVQLIIDILISLQIIYYK", "length": 303 }, "evidence": [ { "id": "A0A8M9PH02", "url": "https://omabrowser.org/oma/group/A0A8M9PH02/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5M880-1", "protein_name": "Solute carrier family 66 member 2", "gene_name": "Slc66a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAEGLGWLLVPLHQLVSWVAAGAMVFGGVVPYIPQYRDIRRTQNADGFSTHVCLVLLVANILRILFWFGRHFESPLLWQSIVMILTMLLMLKLCTEVRVANELNVKRRSFAATDSKDEELRVPPRRPYLDFDPHHFWHWSSFADYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYRNYRHRSTEGMSLKMVLMWTSGDTFKTAYFLLNGAPLQFSVCGLLQVMVDLAILGQAYAFAHHPQKPAPHAVHPASAKAL", "length": 271 }, "evidence": [ { "id": "A0A8M9PH02", "url": "https://omabrowser.org/oma/group/A0A8M9PH02/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XM9-1", "protein_name": "Solute carrier family 66 member 2", "gene_name": "Slc66a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAEGLGWLLVPLHQLVSWVAAGAMVFGGVVPYIPQYRDIRRTQNADGFSTHVCLVLLVANILRILFWFGRHFESPLLWQSIVMILTMLLMLKLCTEVRVANELNIKRRSFAATDSKDEELRVPPRRPYLDFDPHHFWHWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYRNYCHRSTEGMSLKMVLMWTSGDTFKTAYFLLNGAPLQFSVCGLLQVMVDLVILGQAYAFAHHPQKPAAHAVHPASTKAL", "length": 271 }, "evidence": [ { "id": "A0A8M9PH02", "url": "https://omabrowser.org/oma/group/A0A8M9PH02/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N2U9-1", "protein_name": "Solute carrier family 66 member 2", "gene_name": "SLC66A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAEGLDWLLVPLHQLVSWGAAAAMVFGGVVPYVPQYRDIRRTQNADGFSTYVCLVLLVANILRILFWFGRRFESPLLWQSAIMILTMLLMLKLCTEVRVANELNARRRSFTAADSKDEEVKVAPRRSFLDFDPHHFWQWSSFSDYVQCVLAFTGVAGYITYLSIDSALFVETLGFLAVLTEAMLGVPQLYRNHRHQSTEGMSIKMVLMWTSGDAFKTAYFLLKGAPLQFSVCGLLQVLVDLAILGQAYAFARHPQKPAPHAVHPTGTKAL", "length": 271 }, "evidence": [ { "id": "A0A8M9PH02", "url": "https://omabrowser.org/oma/group/A0A8M9PH02/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PH02", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PH02", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02" } ], "pmid": "" }, { "name": "trans-Golgi network membrane", "id": "GO:0032588", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032588", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PH02", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PH02", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "phospholipid translocation", "id": "GO:0045332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045332", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PH02", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH02" } ], "pmid": "" }, { "name": "retrograde transport, endosome to Golgi", "id": "GO:0042147", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042147", "evidence": [ { "database": "UniProtKB", "id": 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This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322333" } ] } ], "disease": [ { "disease_id": "DOID:0080490", "recommended_name": { "id": "DOID:0080490", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080490", "name": "mucolipidosis type IV", "description": "A mucolipidosis that is characterized by delayed development and vision impairment that worsens over time." }, "synonyms": [ { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "mucolipidosis type IV", "description": "A lysosomal disease characterized by psychomotor delay, progressive visual impairment, and achlorhydria." }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "ML 4", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "ML IV", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "ML4", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "MLIV", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "Mucolipidosis IV", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "mucolipidosis IV", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "mucolipidosis type 4", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "mucolipidosis type IV", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "sialolipidosis", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "Berman syndrome", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "ganglioside neuraminidase deficiency", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "ganglioside sialidase deficiency", "description": "" }, { "id": "MIM:252650", "resource": "MIM", "url": "https://www.omim.org/entry/252650", "name": "Mucolipidosis 4", "description": "Mucolipidosis 4" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080490", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080490" } ] }, { "disease_id": "DOID:3343", "recommended_name": { "id": "DOID:3343", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3343", "name": "glycoproteinosis", "description": "A mucolipidosis that is characterized by a deficiency of the enzyme alpha-N -acetyl neuraminidase (sialidase)." }, "synonyms": [ { "id": "DOID:3343", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3343", "name": "Mucolipidosis type I", "description": "" }, { "id": "DOID:3343", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3343", "name": "sialidosis", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis type 2", "description": "A rare lysosomal storage disease, and the severe, early onset form of sialidosis characterized by a progressively severe mucopolysaccharidosis-like phenotype (coarse facies, dysostosis multiplex, hepatosplenomegaly), macular cherry-red spots as well as psychomotor and developmental delay. 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12127:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21381", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21381", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322333", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P7U6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7U6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P7U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7U6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H931", "url": "https://www.uniprot.org/uniprotkb/A0AC58H931", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H931-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H931-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H933", "url": "https://www.uniprot.org/uniprotkb/A0AC58H933", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H933-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H933-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FE44", "url": "https://www.uniprot.org/uniprotkb/E7FE44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FE44-1", "url": "https://www.uniprot.org/uniprotkb/E7FE44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-121116-4", "url": "https://zfin.org/ZDB-GENE-121116-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSDRASHTHESATLLDPECVESLRRKLKYFFMSPCQKYSTRGRIPWKMMLQILKIVIITVQLVSFGLSNEMMVTFKEENLIAFKHFFLKNYKDSNKHYALYTKHEVHDHILYTIRRYLQLQNLTIGNQALEMIDGLATPLSLCQQLYRHARVVPSNETFEIDPHVETECVSVYPLSPITTDSLENSLNLTLDFQRLLAVNIYLKIKAINIQTVRHQELPDCYDFSINIMFDNRAHSGQIKISLSSGVQINVCKDWNISGSTDSHFALIVVFDCLIICFCLLSLILCTRSVHTGFLLQTEYRRFMSSQHSKSVSWSERLEFINGWYILIIISDALTIAGSILKICIQSKELTSYDVCSILLGTATMLVWIGVMRYLSFFQKYYILILTLKAALPNVIRFSICAVMIYLSYCFCGWIVLGPHHENFRTFSRVAGCLFSMINGDEIYSTFTKLREYSTLVWLFSRLYVYSFIPVFTYMVLSVFIALITDTYETIRHYQKHGAPLSELQAFIADCRDPRNYDKNTTNEDEESSSFCCLCAPCVFCT", "length": 542, "header": "tr|A0A8M9P7U6-1|A0A8M9P7U6_DANRE Isoform 1 of Mucolipin-3 isoform X1 OS=Danio rerio OX=7955 GN=mcoln3a PE=4 SV=1 CANONICAL=A0A8M9P7U6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P7U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7U6/entry#A0A8M9P7U6-1", "sequence": { "sequence": "MSDRASHTHESATLLDPECVESLRRKLKYFFMSPCQKYSTRGRIPWKMMLQILKIVIITVQLVSFGLSNEMMVTFKEENLIAFKHFFLKNYKDSNKHYALYTKHEVHDHILYTIRRYLQLQNLTIGNQALEMIDGLATPLSLCQQLYRHARVVPSNETFEIDPHVETECVSVYPLSPITTDSLENSLNLTLDFQRLLAVNIYLKIKAINIQTVRHQELPDCYDFSINIMFDNRAHSGQIKISLSSGVQINVCKDWNISGSTDSHFALIVVFDCLIICFCLLSLILCTRSVHTGFLLQTEYRRFMSSQHSKSVSWSERLEFINGWYILIIISDALTIAGSILKICIQSKELTSYDVCSILLGTATMLVWIGVMRYLSFFQKYYILILTLKAALPNVIRFSICAVMIYLSYCFCGWIVLGPHHENFRTFSRVAGCLFSMINGDEIYSTFTKLREYSTLVWLFSRLYVYSFIPVFTYMVLSVFIALITDTYETIRHYQKHGAPLSELQAFIADCRDPRNYDKNTTNEDEESSSFCCLCAPCVFCT", "length": 542, "header": "tr|A0A8M9P7U6-1|A0A8M9P7U6_DANRE Isoform 1 of Mucolipin-3 isoform X1 OS=Danio rerio OX=7955 GN=mcoln3a PE=4 SV=1 CANONICAL=A0A8M9P7U6-1" }, "locus": {} }, { "isoform_ac": "A0AC58H931-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7U6/entry#A0AC58H931-1", "sequence": { "sequence": "MFDNRAHSGQIKISLSSGVQINVCKDWNISGSNSHFALIVVFDCLIICFCLLSLILCTRSVHTGFLLQTEYRRFMSSQHSKSVSWSERLEFINGWYILIIISDALTIAGSILKICIQSKELTSYDVCSILLGTATMLVWIGVMRYLSFFQKYYILILTLKAALPNVIRFSICAVMIYLSYCFCGWIVLGPHHENFRTFSRVAGCLFSMINGDEIYSTFTKLREYSTLVWLFSRLYVYSFIPVFTYMVLSVFIALITDTYETIRHYQKHGAPLSELQAFIADCRDPRNYDKNTTNEDEESSSFCCLCAPCVFCT", "length": 313, "header": "tr|A0AC58H931-1|A0AC58H931_DANRE Computationally mapped isoform of Mucolipin-3 isoform X4 OS=Danio rerio OX=7955 GN=mcoln3a PE=4 SV=1 CANONICAL=A0A8M9P7U6-1" }, "locus": {} }, { "isoform_ac": "A0AC58H933-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7U6/entry#A0AC58H933-1", "sequence": { "sequence": "MFDNRAHSGQIKISLSSGVQINVCKDWNISGSTDSHFALIVVFDCLIICFCLLSLILCTRSVHTGFLLQTEYRRFMSSQHSKSVSWSERLEFINGWYILIIISDALTIAGSILKICIQSKELTSYDVCSILLGTATMLVWIGVMRYLSFFQKYYILILTLKAALPNVIRFSICAVMIYLSYCFCGWIVLGPHHENFRTFSRVAGCLFSMINGDEIYSTFTKLREYSTLVWLFSRLYVYSFIPVFTYMVLSVFIALITDTYETIRHYQKHGAPLSELQAFIADCRDPRNYDKNTTNEDEESSSFCCLCAPCVFCT", "length": 314, "header": "tr|A0AC58H933-1|A0AC58H933_DANRE Computationally mapped isoform of Mucolipin-3 isoform X3 OS=Danio rerio OX=7955 GN=mcoln3a PE=4 SV=1 CANONICAL=A0A8M9P7U6-1" }, "locus": {} }, { "isoform_ac": "E7FE44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7U6/entry#E7FE44-1", "sequence": { "sequence": "MSDRASHTHESATLLDPECVESLRRKLKYFFMSPCQKYSTRGRIPWKMMLQILKIVIITVQLVSFGLSNEMMVTFKEENLIAFKHFFLKNYKDSNKHYALYTKHEVHDHILYTIRRYLQLQNLTIGNQALEMIDGLATPLSLCQQLYRHARVVPSNETFEIDPHVETECVSVYPLSPITTDSLENSLNLTLDFQRLLAVNIYLKIKAINIQTVRHQELPDCYDFSINIMFDNRAHSGQIKISLSSGVQINVCKDWNISGSNSHFALIVVFDCLIICFCLLSLILCTRSVHTGFLLQTEYRRFMSSQHSKSVSWSERLEFINGWYILIIISDALTIAGSILKICIQSKELTSYDVCSILLGTATMLVWIGVMRYLSFFQKYYILILTLKAALPNVIRFSICAVMIYLSYCFCGWIVLGPHHENFRTFSRVAGCLFSMINGDEIYSTFTKLREYSTLVWLFSRLYVYSFIPVFTYMVLSVFIALITDTYETIRHYQKHGAPLSELQAFIADCRDPRNYDKNTTNEDEESSSFCCLCAPCVFCT", "length": 541, "header": "tr|E7FE44-1|A0A8M9P7U6_DANRE Computationally mapped isoform of Mucolipin-3 isoform X1 OS=Danio rerio OX=7955 GN=mcoln3a PE=4 SV=1 CANONICAL=A0A8M9P7U6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100334819", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100334819", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZXW7-1", "protein_name": "Mucolipin TRP cation channel 3", "gene_name": "Mcoln3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPYSRISLRNSLDGGFLLSDDSSLCPVDLKLPSTPIGPLKTMLLVDREMANPEVVVSSCSSHQDESPCTFYPSSSQSEQLLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQNDVYDQIIFAVTRYLQLRNISVGNHAYENKGTKQSAMAVCQHFYRQGTICPGNDTFDIDPEVETDCFLIEPEEAFHMGTPGENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLSSLVLCARSVIRGLQLQQEFVNFFLLHYKKEVSASDQMEFINGWYIMIIVSDILTIVGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHEKFRSLNKVSECLFSLINGDDMFSTFAKMQQKSYLVWLFSRVYLYSFISLFIYMILSLFIALITDTYETIKHYQQDGFPETELRKFIAECKDLPNSGKYRLEDDPPGSLFCCCKK", "length": 601 }, "evidence": [ { "id": "HGNC:13358", "url": "https://alliancegenome.org/gene/HGNC:13358#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121116-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121116-4#orthology", "database": "AGR" }, { "id": "RGD:1308420", "url": "https://alliancegenome.org/gene/RGD:1308420#orthology", "database": "AGR" }, { "id": "MGI:1890500", "url": "https://alliancegenome.org/gene/MGI:1890500#orthology", "database": "AGR" }, { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G3L4-1", "protein_name": "Mucolipin TRP cation channel 1", "gene_name": "Mcoln1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMLPRTWAVETEQLLTPNPGYGTQAGTSPAPTTPPEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLVVTFREENTIAFRHLFLLGYSDGSDDTFAAYTREQLYQAIFYAVDQYLTLPEISLGRYAYVRGGGGPWANGSALALCQRYYHRGHVDPANDTFDIDPRVVTDCIQVDPPDRPPDIPSEDLDFLDGSTSYKNITLKFHKLINVTIHFQLKTINLQSLINNEIPDCYTFSILITFDNKAHSGRIPIRLETQTHIQECKHPSVSRHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVVFMWRRRGREISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLVWVGVIRYLTFFHKYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGTGTEKSELQAYIEQCQDSPTSGKFRRGSGSTCSLLCCCGRNSPEDHSLLVN", "length": 579 }, "evidence": [ { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PLH2-1", "protein_name": "Mucolipin-3 isoform X1", "gene_name": "mcoln3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDDSREDYLCINDPNGNWSECEAHVDPALEAFRRKLKYFFMNPCDKYKARQRKPWKLFLQIVKIAVVTVQLVSFGLSNQMVVQFKEENLLTFRHLFLKNYSESNTNTYAIYTQLDVYTHITHIVQQFLMLPSITVGNHEYEQEGDVYTPLCICQQFYHNGSISPANETFDIDSRVDQECSLIYPQDPFTESPLNFTLHFERLLSVTVNFTLKAINLETVEYHELPDCYVFNIMIQFDNKAHSGRILVDLDNEVHIYECSDWSMTGASARNMYMMVLFDAVVILILSTSLLLCIRSVKAGVLLQKEYSEFSLRRYRKCVSLSERLEFINGWYLLIIVSDVLTISGSVLKIVIQLKAVASYDLCSILLGTGTMLVWIGVLRYMGYLKKYNSMLCVCCVVQILIITLRVALPNVIRFTCCAAMIYLGYCFCGWIVLGPYHTKFRTLNTVSESLFSLINGDDMFATFKNMQQKSFVVWLFSRLYLYTFVSLFIYMVLSLFITLITDTYDTIKHQQLDGEPVSDLQAFVLQCKDLPDSGEFSVEKTNSISSTGGGKLMCCCSHRSSDSDEDTHFSECSS", "length": 574 }, "evidence": [ { "id": "HGNC:13358", "url": "https://alliancegenome.org/gene/HGNC:13358#orthology", "database": "AGR" }, { "id": "RGD:1308420", "url": "https://alliancegenome.org/gene/RGD:1308420#orthology", "database": "AGR" }, { "id": "MGI:1890500", "url": "https://alliancegenome.org/gene/MGI:1890500#orthology", "database": "AGR" }, { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8IZK6-1", "protein_name": "Mucolipin-2", "gene_name": "MCOLN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARQPYRFPQARIPERGSGVFRLTVRNAMAHRDSEMKEECLREDLKFYFMSPCEKYRARRQIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGYSGTDEDDYSCSVYTQEDAYESIFFAINQYHQLKDITLGTLGYGENEDNRIGLKVCKQHYKKGTMFPSNETLNIDNDVELDCVQLDLQDLSKKPPDWKNSSFFRLEFYRLLQVEISFHLKGIDLQTIHSRELPDCYVFQNTIIFDNKAHSGKIKIYFDSDAKIEECKDLNIFGSTQKNAQYVLVFDAFVIVICLASLILCTRSIVLALRLRKRFLNFFLEKYKRPVCDTDQWEFINGWYVLVIISDLMTIIGSILKMEIKAKNLTNYDLCSIFLGTSTLLVWVGVIRYLGYFQAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHDKFENLNTVAECLFSLVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQKESSAFLSCICCRRRKRSDDHLIPIS", "length": 566 }, "evidence": [ { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K595-1", "protein_name": "Mucolipin-2", "gene_name": "Mcoln2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGDEETLDLPAWNRVPDLTWGPHHRSAMASLDSEVREECLREDLKFYFMSPCEKYRARRQIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGFSGVDEDDYSCSIYTQENTYESIFFAIKQYRHLKNISLATLGYGESEDNRTGLKVCKQHYKTGAMFSSNETLNIDSDIETDCIHLDLQVLTTEPEDWAQTSFFRLDFYRLVQVDISFALKGIDLQAVHSREIPDCYLFQNTITFDNTAHSGKIKIYLNSEANIEECKNMNISGSTQRSTHYLLVFDVFVIMICLASLILCTRSIVLALRLRKRFLNFFLEKYKQRVCGADQWEFVNGWYVLVTISDLMTIIGSILKMEIKAKKLTNYDVCSILLGTSTLFVWVGVIRYLGYFQTYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHEKFENLNIVAECLFSLVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMVLSLFIALITDSYHTIKKYQQHGFPETDLQKFLKESGSKDGYQKQPSALLSCLCCLRRRRSNDHLILID", "length": 566 }, "evidence": [ { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4F0-1", "protein_name": "Mucolipin-3", "gene_name": "Mcoln3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANPEVLVSSCRARQDESPCTFHPSSSPSEQLLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQSEVYDQIIFAVTQYLQLQNISVGNHAYENKGTKQSAMAICQHFYRQGTICPGNDTFDIDPEVETECFLVEPDEASHLGTPGENKLNLSLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIKECKDWHVSGSIQKNTHYMMIFDAFVILTCLASLVLCARSVIRGLQLQQEFVNFFLLHYKKEVSASDQMEFINGWYIMIIISDILTIVGSVLKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVMRFCCCAAMIYLGYCFCGWIVLGPYHEKFRSLNRVSECLFSLINGDDMFSTFAKMQQKSYLVWLFSRVYLYSFISLFIYMILSLFIALITDTYETIKHYQQDGFPETELRKFIAECKDLPNSGKYRLEDDPPGSLLCCCKK", "length": 553 }, "evidence": [ { "id": "HGNC:13358", "url": "https://alliancegenome.org/gene/HGNC:13358#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121116-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121116-4#orthology", "database": "AGR" }, { "id": "RGD:1308420", "url": "https://alliancegenome.org/gene/RGD:1308420#orthology", "database": "AGR" }, { "id": "MGI:1890500", "url": "https://alliancegenome.org/gene/MGI:1890500#orthology", "database": "AGR" }, { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TDD5-1", "protein_name": "Mucolipin-3", "gene_name": "MCOLN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLEDDPPVSLFCCCKK", "length": 553 }, "evidence": [ { "id": "HGNC:13358", "url": "https://alliancegenome.org/gene/HGNC:13358#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121116-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121116-4#orthology", "database": "AGR" }, { "id": "RGD:1308420", "url": "https://alliancegenome.org/gene/RGD:1308420#orthology", "database": "AGR" }, { "id": "MGI:1890500", "url": "https://alliancegenome.org/gene/MGI:1890500#orthology", "database": "AGR" }, { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99J21-1", "protein_name": "Mucolipin-1", "gene_name": "Mcoln1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATPAGRRASETERLLTPNPGYGTQVGTSPAPTTPTEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLVVTFREENTIAFRHLFLLGYSDGSDDTFAAYTQEQLYQAIFYAVDQYLILPEISLGRYAYVRGGGGPWANGSALALCQRYYHRGHVDPANDTFDIDPRVVTDCIQVDPPDRPPDIPSEDLDFLDGSASYKNLTLKFHKLINVTIHFQLKTINLQSLINNEIPDCYTFSILITFDNKAHSGRIPIRLETKTHIQECKHPSVSRHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVVFMWRRRGREISLWERLEFVNGWYILLVTSDVLTISGTVMKIGIEAKNLASYDVCSILLGTSTLLVWVGVIRYLTFFHKYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGHSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGTGTEKSELQAYIEQCQDSPTSGKFRRGSGSACSLFCCCGRDSPEDHSLLVN", "length": 580 }, "evidence": [ { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZU1-1", "protein_name": "Mucolipin-1", "gene_name": "MCOLN1", "tax_id": 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"protein_name": "Transient receptor potential cation channel, mucolipin", "gene_name": "Trpml", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQSYGPGAQTAPAVKRRTDSYEAAQQQQQSPESDEEYVNTRILRRQVQLQSTPVAPVVPMPISAGSGTAPPSVDGREEQPEFPGSSAASYQEERMRRKLQFFFMNPIEKWQAKRKFPYKFVVQIVKIFLVTMQLCLFAHSRYNHINYTGDNRFAFSHLFLRGWDSSREVESYPPAVGPFALYLKSEFFDTVQYAVNGYANVSRSIGPYDYPTPNNTMPPLKLCLQNYREGTIFGFNESYIFDPHIDEVCERLPPNVTTIGVENYLRQRDVEVNFASLVSAQLTFKIKTVNFKANGGPLSAPDCFRFDISITFNNRDHDGQMLLSLDAEATRLKCHGATDFISDANFDSMLRSVLNIFVLLTCALSFALCTRALWRAYLLRCTTVNFFRSQFGKELSFDGRLEFVNFWYIMIIFNDVLLIIGSALKEQIEGRYLVVDQWDTCSLFLGIGNLLVWFGVLRYLGFFKTYNVVILTLKKAAPKILRFLIAALLIYAGFVFCGWLILGPYHMKFRSLATTSECLFALINGDDMFATFATLSSKATWLWWFCQIYLYSFISLYIYVVLSLFIAVIMDAYDTIKAYYKDGFPTTDLKAFVGTRTAEDISSGVFMTDLDDFDQTSFLDVVKSICCCGRCGRHQEPAQPNSGYTSLSSIMK", "length": 652 }, "evidence": [ { "id": "HGNC:13358", "url": "https://alliancegenome.org/gene/HGNC:13358#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121116-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121116-4#orthology", "database": "AGR" }, { "id": "RGD:1308420", "url": "https://alliancegenome.org/gene/RGD:1308420#orthology", "database": "AGR" }, { "id": "MGI:1890500", "url": "https://alliancegenome.org/gene/MGI:1890500#orthology", "database": "AGR" }, { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P7U6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7U6" } ], "pmid": "" }, { "name": "endosome membrane", "id": 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"https://www.uniprot.org/uniprotkb/A0A8M9P7U6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 256, "end_pos": 258, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8M9Q2T2-1", "A0AC58II33-1", "A0AC58HSD6-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8M9Q2T2", "gene_name": "trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2T2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9Q2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2T2" } ] } ] }, { "uniprot_ac": "A0AC58HSD6", "gene_name": "trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58HSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HSD6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58HSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HSD6" } ] } ] }, { "uniprot_ac": "A0AC58II33", "gene_name": "pycr1a", "activity": [ { "ec_number": "1.5.1.2", "activity": "L-proline + NAD(+) = (S)-1-pyrroline-5-carboxylate + NADH + 2 H(+).", "evidence": [ { "id": "A0AC58II33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58II33" } ] }, { "ec_number": "1.5.1.2", "activity": "", "evidence": [ { "id": "A0AC58II33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58II33" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P7U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7U6" }, { "id": "PF21381", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21381" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mucolipin extracytosolic", "eco_id": "ECO_0000259", "start_pos": 72, "end_pos": 253, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P7U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7U6" }, { "id": "PF08016", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Polycystin cation channel PKD1/PKD2", "eco_id": "ECO_0000259", "start_pos": 355, "end_pos": 491, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 256, "end_pos": 258 }, { "start_pos": 520, "end_pos": 522 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"uniprot_ac": "A0A8M9PJL0", "uniprot_id": "A0A8M9PJL0_DANRE", "mass": { "chemical_mass": 54696.0, "monoisotopic_mass": 54696.0 }, "refseq": { "ac": "XP_021325018", "name": "mesoderm induction early response protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325018" }, "gene_names": [ { "name": "mier2", "type": "recommended", "evidence": [ { "id": "A0A8M9PJL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" } ] }, { "name": "fd99d08", "type": "synonym", "evidence": [ { "id": "XP_021325018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325018" }, { "id": "A0A8M9PJL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" } ] }, { "name": "mier2", "type": "synonym", "evidence": [ { "id": "XP_021325018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325018" } ] }, { "name": "si:ch211-206a19.3", "type": "synonym", "evidence": [ { "id": "XP_021325018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325018" }, { "id": "A0A8M9PJL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" } ] }, { "name": "wu:fd99d08", "type": "synonym", "evidence": [ { "id": "XP_021325018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325018" }, { "id": "A0A8M9PJL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" } ] } ], "protein_names": [ { "name": "Mesoderm induction early response protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PJL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0/entry#names_and_taxonomy" } ] }, { "name": "mesoderm induction early response protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325018" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325018.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325018" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJL0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mier2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050208-795", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-795", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000071413", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000071413", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "564723", "url": "https://www.ncbi.nlm.nih.gov/gene/564723", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040138", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040138", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564723", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564723", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CIRFLLM", "url": "https://omabrowser.org/oma/group/CIRFLLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PJL0", "url": "https://www.orthodb.org/?gene=A0A8M9PJL0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1Q4S8", "url": "https://www.orthodb.org/?gene=F1Q4S8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10865", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10865", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10865:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10865:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01448", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01448", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325018", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PJL0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TAW2", "url": "https://www.uniprot.org/uniprotkb/A0AB32TAW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TAW2-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TAW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q4S8", "url": "https://www.uniprot.org/uniprotkb/F1Q4S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q4S8-1", "url": "https://www.uniprot.org/uniprotkb/F1Q4S8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050208-795", "url": "https://zfin.org/ZDB-GENE-050208-795", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGSKDQRHSRVDIFHQGYVGPLEALPRATTFLEEDRSLVALRRQAVKMATKSQAGGEMSLEQLLALYGYKMPDPVLQQQEPNELAASLPEITLDKVQIHKDLLSGGEDVDNHSSADDLTLTIKSHASDLLQCHLRGDDKDTSVSCSEDDSESTSIPSSDGRKDIMVGPQYQAVIPSLCTQSFYERAYENEDQLVWTPDVMSSLAVEKFLLDAQRNGSDSGPTNTLTTGDKVKDNEQALYELVKCNFNAEEALRRYRFNVKVFNEELCGWSEEERRYFEHGFRAHGKNFNLIQANKVRTRSVGECVEYYYMWKKSERHEYFTQQATKLGRKKCNLPSGNIEDTEPDGDTGDVEVATQGLPARSSIQLQTPSPPTVMELNKQACERNIGEIDLCAGCCSGPQGEQLFSQFTLPPVLQMPDVVSLSTQLYFSQISRRHSVPSSHLTQGSWEQGFTSFNSGLLLTILHLPAQSVLLHRSFSLTFLYLPHHPS", "length": 488, "header": "tr|A0A8M9PJL0-1|A0A8M9PJL0_DANRE Isoform 1 of Mesoderm induction early response protein 2 isoform X1 OS=Danio rerio OX=7955 GN=mier2 PE=4 SV=2 CANONICAL=A0A8M9PJL0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PJL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0/entry#A0A8M9PJL0-1", "sequence": { "sequence": "MGSKDQRHSRVDIFHQGYVGPLEALPRATTFLEEDRSLVALRRQAVKMATKSQAGGEMSLEQLLALYGYKMPDPVLQQQEPNELAASLPEITLDKVQIHKDLLSGGEDVDNHSSADDLTLTIKSHASDLLQCHLRGDDKDTSVSCSEDDSESTSIPSSDGRKDIMVGPQYQAVIPSLCTQSFYERAYENEDQLVWTPDVMSSLAVEKFLLDAQRNGSDSGPTNTLTTGDKVKDNEQALYELVKCNFNAEEALRRYRFNVKVFNEELCGWSEEERRYFEHGFRAHGKNFNLIQANKVRTRSVGECVEYYYMWKKSERHEYFTQQATKLGRKKCNLPSGNIEDTEPDGDTGDVEVATQGLPARSSIQLQTPSPPTVMELNKQACERNIGEIDLCAGCCSGPQGEQLFSQFTLPPVLQMPDVVSLSTQLYFSQISRRHSVPSSHLTQGSWEQGFTSFNSGLLLTILHLPAQSVLLHRSFSLTFLYLPHHPS", "length": 488, "header": "tr|A0A8M9PJL0-1|A0A8M9PJL0_DANRE Isoform 1 of Mesoderm induction early response protein 2 isoform X1 OS=Danio rerio OX=7955 GN=mier2 PE=4 SV=2 CANONICAL=A0A8M9PJL0-1" }, "locus": {} }, { "isoform_ac": "A0AB32TAW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0/entry#A0AB32TAW2-1", "sequence": { "sequence": "MGSKDQRHSRVDIFHQGYVGPLEALPRATTFLEEDRSLVALRRQAVKMATKSQAGGEMSLEQLLALYGYKMPDPVLQQQEPNELAASLPEITLDKVQIHKDLLSGGEDVDNHSSADDLTLTIKSHASDLLQCHLRGDDKDTSVSCSEDDSESTSIPSSDGRKDIMVGPQYQAVIPSLCTQSFYERAYENEDQLVWTPDVMSSLAVEKFLLDAQRNGSDSGPTNTLTTGDKVKDNEQALYELVKCNFNAEEALRRYRFNVKVFNEELCGWSEEERRYFEHGFRAHGKNFNLIQANKVRTRSVGECVEYYYMWKKSERHEYFTQQATKLGRKKCNLPSGNIEDTEPDGDTGDVEVATQGLPARSSIQLQTPSPPTVMELNKQEESLNCAAQFQGRPRRKRTPRFLLKP", "length": 406, "header": "tr|A0AB32TAW2-1|A0AB32TAW2_DANRE Computationally mapped isoform of Mesoderm induction early response protein 2 isoform X2 OS=Danio rerio OX=7955 GN=mier2 PE=4 SV=1 CANONICAL=A0A8M9PJL0-1" }, "locus": {} }, { "isoform_ac": "F1Q4S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0/entry#F1Q4S8-1", "sequence": { "sequence": "MGSKDQRHSRVDIFHQGYVGPLEALPRATTFLEEDRSLVALRRQAVKMATKSQAGGEMSLEQLLALYGYKMPDPVLQQQEPNELAASLPEITLDKVQIHKDLLSGGEDVDNHSSADDLTLTIKSHASDLLQCHLRGDDKDTSVSCSEDDSESTSIPSSDGRKDIMVGPQYQAVIPSLCTQSFYERAYENEDQLVWTPDVMSSLAVEKFLLDAQRNGSDSGPTNTLTTGDKVKDNEQALYELVKCNFNAEEALRRYRFNVKVFNEELCGWSEEERRYFEHGFRAHGKNFNLIQANKVRTRSVGECVEYYYMWKKSERHEYFTQQATKLGRKKCNLPSGNIEDTEPDGDTGDVEVATQGLPTRSSIQLQTPSPPTVMELNKQEESLNCAAQFQGRPRRKRTPRFLLKP", "length": 406, "header": "tr|F1Q4S8-1|A0A8M9PJL0_DANRE Computationally mapped isoform of Mesoderm induction early response protein 2 isoform X1 OS=Danio rerio OX=7955 GN=mier2 PE=4 SV=1 CANONICAL=A0A8M9PJL0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Global analysis of the haematopoietic and endothelial transcriptome during zebrafish development.", "journal": "Mech. Dev.", "date": "2013", "authors": "Cannon J E, Place E S, Eve A M J, Bradshaw C R, Sesay A, Morrell N W, Smith J C", "evidence": [ { "database": "UniProtKB", "id": "F1Q4S8", "url": "https://www.uniprot.org/uniprotkb/F1Q4S8" } ], "reference": [ { "type": "PubMed", "id": "23072875", "url": "https://glygen.org/publication/PubMed/23072875" } ] }, { "title": "A network of epigenetic regulators guides developmental haematopoiesis in vivo.", "journal": "Nat. Cell Biol.", "date": "2013", "authors": "Huang Hsuan-Ting, Kathrein Katie L, Barton Abby, Gitlin Zachary, Huang Yue-Hua, Ward Thomas P, Hofmann Oliver, Dibiase Anthony, Song Anhua, Tyekucheva Svitlana, Hide Winston, Zhou Yi, Zon Leonard I", "evidence": [ { "database": "UniProtKB", "id": "F1Q4S8", "url": "https://www.uniprot.org/uniprotkb/F1Q4S8" } ], "reference": [ { "type": "PubMed", "id": "24240475", "url": "https://glygen.org/publication/PubMed/24240475" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "F1Q4S8", "url": "https://www.uniprot.org/uniprotkb/F1Q4S8" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "F1Q4S8", "url": "https://www.uniprot.org/uniprotkb/F1Q4S8" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Gene duplication of C-type natriuretic peptide-4 (CNP4) in teleost lineage elicits subfunctionalization of ancestral CNP.", "journal": "Cell Tissue Res.", "date": "2022", "authors": "Katayama Yukitoshi, Saito Ami, Ogoshi Maho, Tsuneoka Yousuke, Mukuda Takao, Azuma Morio, Kusakabe Makoto, Takei Yoshio, Tsukada Takehiro", "evidence": [ { "database": "UniProtKB", "id": "F1Q4S8", "url": "https://www.uniprot.org/uniprotkb/F1Q4S8" } ], "reference": [ { "type": "PubMed", "id": "35171324", "url": "https://glygen.org/publication/PubMed/35171324" } ] } ], "pathway": [ { "id": "dre:564723", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564723", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JT20-1", "protein_name": "MIER family member 2", "gene_name": "Mier2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLPVCPHVYISSQDCGCGTRSLHGFLPSPDWPTPFRPTPCLLLNPFTVVSMGSADHQFHLTELLTQNYSLQEGCAEALQGPDRPEEELDKDFIDQSSDMPLDELLALYGYESSEPISEQESEGGDTAPPLPDMTLDKEQIAKDLLSGEEEEETQSSADDLTPSVTSHEASDLFHNQSGSRFLSGDNGPGSSASSDTEEDALPANKCKKEIMVGPQFQADLNILHLNRHCDKIYENEDQLLWSPTVLPEREVEEFLYRAVKRRWQEMAGPQIPEGEVVKDSEQALYELVKCNFNVEEALRRLRFNVKVIRDGLCAWSEEECRNFEHGFRVHGKNFHLIQANKVRTRSVGECVEYYYLWKKSERYDYFAQQTRLGRRKFVSSGTTDTEQDLDGLDPDGHARLQSETRVPVEPLSADIEAGGLDQPGVDSDDLPSSEPGPSPFQQLDEPPAVPSLQQPTSLATSAELPLTELPPAAAAPEPATSPRLAVDLALPEELPLVSSPVALNGDPAEPMAPAQVALSVTEFGLIGIGDVNPFLTGHPACPASTLHAEPLSQCNVMTC", "length": 560 }, "evidence": [ { "id": "HGNC:29210", "url": "https://alliancegenome.org/gene/HGNC:29210#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-795", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-795#orthology", "database": "AGR" }, { "id": "RGD:1307278", "url": "https://alliancegenome.org/gene/RGD:1307278#orthology", "database": "AGR" }, { "id": "MGI:1917677", "url": "https://alliancegenome.org/gene/MGI:1917677#orthology", "database": "AGR" }, { "id": "FB:FBgn0033183", "url": "https://alliancegenome.org/gene/FB:FBgn0033183#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A0V9-1", "protein_name": "Mesoderm induction early response protein 1", "gene_name": "Mier1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVATLRLGLGSPFPSGSAVPGLQLPPQQLRNVCRASWRPQSLAQEAAARLAGRSRLRRRAEAEGRVEGWWSWRKLGRRFGGGGRPRPLPGCESPGCRRMDGASPGGGGSSGGGGSGGGYGVVARFSQCLAEFRTWLRTNWLRFNADKTDVMLKMCIRCLCLIGLQTVSGFFSCQITSHLLSLQVQKWMKCLPAHEGTGGSAASEDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIDELLSLYGYGSTVQLPEEEEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVTSQDAQEIIRPRRCKYFDTNSEIEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGVCRYKENEKVYENDDQLLWDPEYLPEDKVIVFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCSFDTEEALRRLRFNVKAAREELSVWTEEECRNFEQGLKAYGKDFHLIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSTSQSEKEDGTLSNSNQNGVSSNGPGEILNKEEVKVEGLHVNGPTGGNKKPLLTDVDTNGYEENNLATDPKLAHMTARNENDFDEKNERPAKRRRINSSGKESPGSSEFFQEAVSHGKFEEHENTND", "length": 698 }, "evidence": [ { "id": "FB:FBgn0033183", "url": "https://alliancegenome.org/gene/FB:FBgn0033183#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M2BE82-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "mier3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEASLGSSSPVGSLSSEDHDFDPTAEMLIHEYDDERTLEEEELLEGERNFSAELSDLEREGNMPIDELLAMYRYEASVSTGAGSSIDSSSVELADDLPDMTLDKEEIAKDLLSGDYEEETQSSADDLTPSVTSHEATDFFPRTLRSNVTYDGDKESEGEEDGVNSEDSRKEIMVGSQYQAEVPAGLSHYNDDEKVYEEEDQLLWCPDELSEYKVKDYLREALSQSTDDRTHYSTSEHIRDNEQALFELLKCNYDTREALVRYCSNVKTSKEESPPWSEEECRNFEHALQIYEKNFHLIQKHKVQTRTVAECVAFYYMWKKSERFDYFAQQNRFGKKKYSCYPGVTDLMDRLVDEAEGLAVDGSSPVCSAGAGGRLEASAEQQLGLLNSITASDLTALSNSVANVCNGPAEMSCLDSPFFPPLESLHRAALNHDDQLSYGTNGDGVCLNMLDSGFYRSDLGQLSMCSSKDCERPSKRLKMGLSESFINDVDFEGRRAHRITGATMAVSVTDFSGIGSEANAFISSHSRHHQHTALQSD", "length": 538 }, "evidence": [ { "id": "FB:FBgn0033183", "url": "https://alliancegenome.org/gene/FB:FBgn0033183#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z6Z7-1", "protein_name": "Mesoderm induction early response protein 1", "gene_name": "Dmel\\CG1620", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMEFGKSSDHSQHSASEASADSGSLANSDLAVTPTKRERRKSPATSSDNNSTSVQPPMSPSSSVADTTFEPTIDMMVNDFDDEATLNEEEALADMEAHSAEDEIATLREESEMPIEELLAKYGGTAASPAMSSSNRSGSSSRRARRATKRQYQELDTEMAHTSTSTSSSTSQLEKHDGIDQEEEPKEEADKLASPPESGEASSVDTEDAQKYEGIKKQHRSHLLDLYPDESFVDLAPTCGEETERFTPLQTLFDEVEAEEEEESESELDDARKIIMVGHDYQAEIPEGLSQYGDILPYENEDQLIWEPSQVSEREVEEYLAKIQETRSIVPPDDGSETTAGEEGAATGATIEPPAPITAPATPPRAPLATSGAGDQELVVKDNEQALHLLVQCGYDFKEALRRKRMNVLPLTDTMSSWSEDECLKFEEGIQRFGKDFYQIRQNQVRTRTMRELVHFYYLWKKSERRDQSFALNDTIDHMDVFINEAGGGNGSGNGNGAGIVSGTANSNGSCSPHSSNGHSNGDLSALEKDTIASPRKPASKSYSIMTGSQAVGNPSGGNRKRCSSASLPLEDEDNNVEEEPSLSTV", "length": 586 }, "evidence": [ { "id": "HGNC:29210", "url": "https://alliancegenome.org/gene/HGNC:29210#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-795", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-795#orthology", "database": "AGR" }, { "id": "RGD:1307278", "url": "https://alliancegenome.org/gene/RGD:1307278#orthology", "database": "AGR" }, { "id": "MGI:1917677", "url": "https://alliancegenome.org/gene/MGI:1917677#orthology", "database": "AGR" }, { "id": "FB:FBgn0033183", "url": "https://alliancegenome.org/gene/FB:FBgn0033183#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZE77-1", "protein_name": "MIER family member 3", "gene_name": "Mier3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASFGSSSPGIEPRKEPVYSRQALRHIAVCPALGYFKQMITIGSLSSEDHDFDPTAEMLVHDYDDERTLEEEELMGDGKNFSSEIEDLEKEGNMPLEDLLAFYGYESTIPTVANSSANSSPSELADELPDMTLDKEEIAKDLLSGDDEETQSSADDLTPSVTSHETSDFFPRPLRSNTTCDGDKESEIEDVETDSGNSPEDLRKEIMIGLQYQAEIPPYLGEYSGDEKAYENEDQLLWRPDVVLESKVKEYLIETSLRTGNEKVLDRISSGTHTRDNEQALYELLKCNHNVTEAIERYCCNGKASQEGMTAWTEEECRSFEHALMLYGKDFHLIQKNKVRSRTVAECVAFYYMWKKSERYDYFAQQTKFGKKRYNHHPGVTDYMDRLVDETESLGDTVSSSALTSNRPEPIPDQPLNILSSFTASDLTALTNSVATVCNPTDVSCLDDSFSPLGNAPRGQVNHVPVVTEELLTLPSNGESDCFNLFETGFYHSELNPMCSEESERPAKRLKMGIAVPESFMNEVSVNNLGVDFENHTHHITSAKMAVSVADFGSLSASETNGFINAHTLHQHAALHSE", "length": 580 }, "evidence": [ { "id": "FB:FBgn0033183", "url": "https://alliancegenome.org/gene/FB:FBgn0033183#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3U3N0-1", "protein_name": "Mesoderm induction early response protein 2", "gene_name": "Mier2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEASSLERQSPRVASCLVHSLCPREPSLQTTAVVSMGSADHQFNLAELLTQNYNLQEGCAEAPQCPDKPEEELDKDFIDQSSDMPLDELLALYGYESSDPISEQESEGGDTAPALPDMTLDKEQIAKDLLSGEEEEETQSSADDLTPSVTSHEASDLFHNQSGSRFLAGDNGPGSSASSDTEEDALPANKCKKEIMVGPQFQADLNILHLNRHCDKIYENEDQLLWSPSVLPEREVEEFLYRAVKRRWQEMAGPQIPEGEVVKDSEQALYELVKCNFNVEEALRRLRFNVKVIRDGLCAWSEEECRNFEHGFRVHGKNFHLIQANKVRTRSVGECVEYYYLWKKSERYDYFAQQTRLGRRKFVSSGTTDTEQDLDGLDPDGHARLHSEAGVPVEPLNVDIEAGGLDQPGVGSDDLPSSEPGPRPFQQLDEPPAVPSLQQPTSLAASAELPPAAAAAPEPGTSPRLPVDLALPEELPLVSSPVALSEDTAEPMAPAQVALSVTEFGLIGIGDVNPFLTGHPACPTSTLHSEPLSQCNVMTC", "length": 541 }, "evidence": [ { "id": "HGNC:29210", "url": "https://alliancegenome.org/gene/HGNC:29210#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-795", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-795#orthology", "database": "AGR" }, { "id": "RGD:1307278", "url": "https://alliancegenome.org/gene/RGD:1307278#orthology", "database": "AGR" }, { "id": "MGI:1917677", "url": "https://alliancegenome.org/gene/MGI:1917677#orthology", "database": "AGR" }, { "id": "FB:FBgn0033183", "url": "https://alliancegenome.org/gene/FB:FBgn0033183#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3UHF3-1", "protein_name": "Mesoderm induction early response protein 3", "gene_name": "Mier3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEASFGSSSPVGSLSSEDHDFDPTAEMLVHDYDDERTLEEEELMDDGKNFSSEIEDLEKEGNMPLEDLLAFYGYESTIPAVANSSANSSPSELADELPDMTLDKEEIAKDLLSGDDEETQSSADDLTPSVTSHETSEFFPRPLRSNTTCDGDKESEIEDVETDSGNSPEDLRREIMIGLEYQAEIPPYLGEYNGDDEKAYENEDQLLWHPGVLLESKVKEYLVETSLRTGNEKVLDRISSGTHTRDNEQALYELLKCNHNIKEAIERYCCNGKASQEGMTAWTEEECRSFEHALMLHGKDFHLIQKDKVRSRTVAECVAFYYMWKKSERYDYFAQQTKFGKKRYNHHPGVTDYMDRLVDETESLGGTVSSSALTCNRPEPVPDQPLNILSSFTASDLTALTNSVATVCNPTAVNCLDDSFPPLANTPRGHVNHVPVVTEELLTLPSNGESDCFNLFETGFYHSELNPMCSEESERPAKRLKMGIAVPESFMNEVSVNNLGVDFENHTHHITSAKMAVSVADFGSLSANETNGFINAHSLHQHQHAALHSE", "length": 551 }, "evidence": [ { "id": "FB:FBgn0033183", "url": "https://alliancegenome.org/gene/FB:FBgn0033183#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5UAK0-3", "protein_name": "Mesoderm induction early response protein 1", "gene_name": "Mier1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEPSVESSSPGGSATSEDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYDSTVRLPEEEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVTSQDAQEIIRPRRCKYFDTNSEIEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGVCRYKENEKVYENDDQLLWDPECLPEEKVVVFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCSFDTEEALRRLRFNVKAAREELSVWTEEECRNFEQGLKAYGKDFHLIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSNSQSEKEDGAVSSRNQNGVSSNGPGEILNKEEVKVEGLHVNGPTGGNKKPLLTDMDTNGYEANNLTTDPKLAHMTARNENDFDEKNERPAKRRRINSSGKESPGSSEFFQEAVSHGKFEEHENTND", "length": 511 }, "evidence": [ { "id": "FB:FBgn0033183", "url": "https://alliancegenome.org/gene/FB:FBgn0033183#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z3K6-1", "protein_name": "Mesoderm induction early response protein 3", "gene_name": "MIER3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEASFGSSSPVGSLSSEDHDFDPTAEMLVHDYDDERTLEEEEMMDEGKNFSSEIEDLEKEGTMPLEDLLAFYGYEPTIPAVANSSANSSPSELADELPDMTLDKEEIAKDLLSGDDEETQSSADDLTPSVTSHETSDFFPRPLRSNTACDGDKESEVEDVETDSGNSPEDLRKEIMIGLQYQAEIPPYLGEYDGNEKVYENEDQLLWCPDVVLESKVKEYLVETSLRTGSEKIMDRISAGTHTRDNEQALYELLKCNHNIKEAIERYCCNGKASQEGMTAWTEEECRSFEHALMLFGKDFHLIQKNKVRTRTVAECVAFYYMWKKSERYDYFAQQTRFGKKRYNHHPGVTDYMDRLVDETEALGGTVNASALTSNRPEPIPDQQLNILNSFTASDLTALTNSVATVCDPTDVNCLDDSFPPLGNTPRGQVNHVPVVTEELLTLPSNGESDCFNLFETGFYHSELNPMNMCSEESERPAKRLKMGIAVPESFMNEVSVNNLGVDFENHTHHITSAKMAVSVADFGSLSANETNGFISAHALHQHAALHSE", "length": 550 }, "evidence": [ { "id": "FB:FBgn0033183", "url": "https://alliancegenome.org/gene/FB:FBgn0033183#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N108-11", "protein_name": "Mesoderm induction early response protein 1", "gene_name": "MIER1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEPSVESSSPGGSATSDDHEFDPSADMLVHDFDDERTLEEEEMMEGETNFSSEIEDLAREGDMPIHELLSLYGYGSTVRLPEEDEEEEEEEEEGEDDEDADNDDNSGCSGENKEENIKDSSGQEDETQSSNDDPSQSVASQDAQEIIRPRRCKYFDTNSEVEEESEEDEDYIPSEDWKKEIMVGSMFQAEIPVGICRYKENEKVYENDDQLLWDPEYLPEDKVIIFLKDASRRTGDEKGVEAIPEGSHIKDNEQALYELVKCNFDTEEALRRLRFNVKAAREELSVWTEEECRNFEQGLKAYGKDFHLIQANKVRTRSVGECVAFYYMWKKSERYDFFAQQTRFGKKKYNLHPGVTDYMDRLLDESESAASSRAPSPPPTASNSSNSQSEKEDGTVSTANQNGVSSNGPGEILNKEEVKVEGLHINGPTGGNKKPLHADMDTNGYETDNLTTDPKLAHMTARNENDFDEKSERPAKRRRVNSNGKESPGSSEFFQEAVSHGKFEELENTDD", "length": 512 }, "evidence": [ { "id": "FB:FBgn0033183", "url": "https://alliancegenome.org/gene/FB:FBgn0033183#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N344-1", "protein_name": "Mesoderm induction early response protein 2", "gene_name": "MIER2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEASSLGRQSPRVVSCLEHSLCPGEPGLQTTAVVSMGSGDHQFNLAEILSQNYSVRGECEEASRCPDKPKEELEKDFISQSNDMPFDELLALYGYEASDPISDRESEGGDVAPNLPDMTLDKEQIAKDLLSGEEEEETQSSADDLTPSVTSHEASDLFPNRSGSRFLADEDREPGSSASSDTEEDSLPANKCKKEIMVGPQFQADLSNLHLNRHCEKIYENEDQLLWDPSVLPEREVEEFLYRAVKRRWHEMAGPQLPEGEAVKDSEQALYELVKCNFNVEEALRRLRFNVKVIRDGLCAWSEEECRNFEHGFRVHGKNFHLIQANKVRTRSVGECVEYYYLWKKSERYDYFAQQTRLGRRKYVPSGTTDADQDLDGSDPDGPGRPRPEQDTLTGMRTDPLSVDGTAGGLDEPGVASDGLPSSEPGPCSFQQLDESPAVPLSHRPPALADPASYQPAVTAPEPDASPRLAVDFALPKELPLISSHVDLSGDPEETVAPAQVALSVTEFGLIGIGDVNPFLAAHPTCPAPGLHSEPLSHCNVMTC", "length": 545 }, "evidence": [ { "id": "HGNC:29210", "url": "https://alliancegenome.org/gene/HGNC:29210#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-795", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-795#orthology", "database": "AGR" }, { "id": "RGD:1307278", "url": "https://alliancegenome.org/gene/RGD:1307278#orthology", "database": "AGR" }, { "id": "MGI:1917677", "url": "https://alliancegenome.org/gene/MGI:1917677#orthology", "database": "AGR" }, { "id": "FB:FBgn0033183", "url": "https://alliancegenome.org/gene/FB:FBgn0033183#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJL0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJL0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" } ], "pmid": "" }, { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJL0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJL0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" } ], "pmid": "" }, { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJL0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJL0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" } ], "pmid": "" }, { "name": "histone deacetylase binding", "id": "GO:0042826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042826", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJL0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PJL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" }, { "id": "PS51156", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51156" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELM2", "eco_id": "ECO_0000259", "start_pos": 162, "end_pos": 259, "start_aa": "Lys", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PJL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJL0" }, { "id": "PS51293", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51293" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SANT", "eco_id": "ECO_0000259", "start_pos": 264, "end_pos": 316, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 215, "end_pos": 217 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9P756-1", "uniprot_ac": "A0A8M9P756", "uniprot_id": "A0A8M9P756_DANRE", "mass": { "chemical_mass": 50411.0, "monoisotopic_mass": 50411.0 }, "refseq": { "ac": "XP_021322033", "name": "uncharacterized protein atf5b isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322033" }, "gene_names": [ { "name": "atf5b", "type": "recommended", "evidence": [ { "id": "A0A8M9P756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756" } ] }, { "name": "atf5b", "type": "synonym", "evidence": [ { "id": "XP_021322033", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322033" } ] } ], "protein_names": [ { "name": "Uncharacterized protein atf5b isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein atf5b isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322033", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322033" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322033", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322033" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P756", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "atf5b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-2637", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2637", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P756", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P756", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000077785", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077785", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14692", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14692", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "567253", "url": "https://www.ncbi.nlm.nih.gov/gene/567253", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567253", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567253", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KPSLVMG", "url": "https://omabrowser.org/oma/group/KPSLVMG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P756", "url": "https://www.orthodb.org/?gene=A0A8M9P756", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1QGR6", "url": "https://www.orthodb.org/?gene=F1QGR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13044", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13044", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13044:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13044:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322033", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322033", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P756", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P756-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QGR6", "url": "https://www.uniprot.org/uniprotkb/F1QGR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QGR6-1", "url": "https://www.uniprot.org/uniprotkb/F1QGR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-2637", "url": "https://zfin.org/ZDB-GENE-030131-2637", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAYNWMTKTFDTYPNSTSTESSPGSSIPPSPLEHDVQMPSDLEVMTNLLKEELAQLEDYYLYESAPMKLEKWQKCDKSLQAMATQSYYQLPCASYNVNQSETNPRLVSLAAGELDLRGFCGGSVNRPKMSRPAPYSYIRTHCNSQRISSNGCKDVEVFEKETWTFKGTHSGYAELAFDQCSVDKSFGKNHGSAKKVRECAILLKEEEKSCFSEDVFYRAEMMRSYDLAGSLEPHHRRESQCHGMKMLGHDGIAMPILQCAENESCPPPYKQSDVAECYFHQITANLEPYHGFMNEIDQPIRTDIQNNDYLHHECLGDQSFECLSGDSVGSSLELPVQKPLQRSRESQCVFKPDVKVGVERNHGERKQKKRDQNKSAAHRYRQRKRAEQDCLEEELHGLEGRNRELRDKAESVEREIQYVKDLLIEVYKARSQRLKEDSSA", "length": 440, "header": "tr|A0A8M9P756-1|A0A8M9P756_DANRE Isoform 1 of Uncharacterized protein atf5b isoform X1 OS=Danio rerio OX=7955 GN=atf5b PE=3 SV=1 CANONICAL=A0A8M9P756-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P756-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756/entry#A0A8M9P756-1", "sequence": { "sequence": "MAYNWMTKTFDTYPNSTSTESSPGSSIPPSPLEHDVQMPSDLEVMTNLLKEELAQLEDYYLYESAPMKLEKWQKCDKSLQAMATQSYYQLPCASYNVNQSETNPRLVSLAAGELDLRGFCGGSVNRPKMSRPAPYSYIRTHCNSQRISSNGCKDVEVFEKETWTFKGTHSGYAELAFDQCSVDKSFGKNHGSAKKVRECAILLKEEEKSCFSEDVFYRAEMMRSYDLAGSLEPHHRRESQCHGMKMLGHDGIAMPILQCAENESCPPPYKQSDVAECYFHQITANLEPYHGFMNEIDQPIRTDIQNNDYLHHECLGDQSFECLSGDSVGSSLELPVQKPLQRSRESQCVFKPDVKVGVERNHGERKQKKRDQNKSAAHRYRQRKRAEQDCLEEELHGLEGRNRELRDKAESVEREIQYVKDLLIEVYKARSQRLKEDSSA", "length": 440, "header": "tr|A0A8M9P756-1|A0A8M9P756_DANRE Isoform 1 of Uncharacterized protein atf5b isoform X1 OS=Danio rerio OX=7955 GN=atf5b PE=3 SV=1 CANONICAL=A0A8M9P756-1" }, "locus": {} }, { "isoform_ac": "F1QGR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756/entry#F1QGR6-1", "sequence": { "sequence": "MTKTFDTYPNSTSTESSPGSSIPPSPLEHDVQMPSDLEVMTNLLKEELAQLEDYYLYESAPMKLEKWQKCDKSLQAMATQSYYQLPCASYNVNQSETNPRLVSLAAGELDLRGFCGGSVNRPKMSRPAPYSYIRTHCNSQRISSNGCKDVEVFEKETWTFKGTHSGYAELAFDQCSVDKSFGKNHGSAKKVRECAILLKEEEKSCFSEDVFYRAEMMRSYDLAGSLEPHHRRESQCHGMKMLGHDGIAMPILQCAENESCPPPYKQSDVAECYFHQITANLEPYHGFMNEIDQPIRTDIQNNDYLHHECLGDQSFECLSGDSVGSSLELPVQKPLQRSRESQCVFKPDVKVGVERNHGERKQKKRDQNKSAAHRYRQRKRAEQDCLEEELHGLEGRNRELRDKAESVEREIQYVKDLLIEVYKARSQRLKEDSSA", "length": 435, "header": "tr|F1QGR6-1|A0A8M9P756_DANRE Computationally mapped isoform of Uncharacterized protein atf5b isoform X1 OS=Danio rerio OX=7955 GN=atf5b PE=3 SV=2 CANONICAL=A0A8M9P756-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:567253", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567253", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O70191-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-5", "gene_name": "Atf5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLLATLGLELDRALLPASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTERVDFTALLPLEAPLPPGTLPPPSPAPPDLEAMASLLKKELEQMEDFFLDAPLLPPPSPPPPPPPAAAPSLPLPLPLPTFDLPQPPTLDTLDLLAVYCRSEAGPGDSGLSTLPVPQQPPPLAPLPSPARPAPYPSPASTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRST", "length": 283 }, "evidence": [ { "id": "HGNC:790", "url": "https://alliancegenome.org/gene/HGNC:790#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2637", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2637#orthology", "database": "AGR" }, { "id": "MGI:2141857", "url": "https://alliancegenome.org/gene/MGI:2141857#orthology", "database": "AGR" }, { "id": "RGD:628902", "url": "https://alliancegenome.org/gene/RGD:628902#orthology", "database": "AGR" }, { "id": "FB:FBgn0000370", "url": "https://alliancegenome.org/gene/FB:FBgn0000370#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P18848-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-4", "gene_name": "ATF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTEMSFLSSEVLVGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAKAGSSEWLAVDGLVSPSNNSKEDAFSGTDWMLEKMDLKEFDLDALLGIDDLETMPDDLLTTLDDTCDLFAPLVQETNKQPPQTVNPIGHLPESLTKPDQVAPFTFLQPLPLSPGVLSSTPDHSFSLELGSEVDITEGDRKPDYTAYVAMIPQCIKEEDTPSDNDSGICMSPESYLGSPQHSPSTRGSPNRSLPSPGVLCGSARPKPYDPPGEKMVAAKVKGEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKERADSLAKEIQYLKDLIEEVRKARGKKRVP", "length": 351 }, "evidence": [ { "id": "FB:FBgn0000370", "url": "https://alliancegenome.org/gene/FB:FBgn0000370#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q06507-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-4", "gene_name": "Atf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEMSFLNSEVLAGDLMSPFDQSGLGAEESLGLLDDYLEVAKHLKPHGFSSDKAGSSEWPAMDDGLASASDTGKEDAFSGTDWMLEKMDLKEFDFDALFRMDDLETMPDELLTTLDDTCDLFAPLVQETNKEPPQTVNPIGHLPESLIKVDQVAPFTFLQPFPCSPGVLSSTPEHSFSLELGSEVDISEGDRKPDSAAYITLIPPCVKEEDTPSDNDSGICMSPESYLGSPQHSPSTSRAPPDNLPSPGGSRGSPRPKPYDPPGVSLTAKVKTEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKEKADSLAKEIQYLKDLIEEVRKARGKKRVP", "length": 349 }, "evidence": [ { "id": "FB:FBgn0000370", "url": "https://alliancegenome.org/gene/FB:FBgn0000370#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6NW59-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-4", "gene_name": "atf4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLCVGDAGALLLGPWPLTADPQGPLLDQDEESSVLEGSWSPSSSSLSSFSPPASGDAPSELLSLSWQPSDVLLTEQSTAGDVFPGMDWMTEKLDLNDFDLDSLIGSCDSEDSPGSPEDLLACLDSSMDLDLDSLPFGSADLDLPLGLDLPLPEEIKSEPLSPAPSVPSPPEEAPQDEHTEVPVLHPAGIMLSLSPSHIVVLLTPKEEQNISDCSDSDSGISVSGSPAHQSDLEPSSRAKPYSRPDPEASPALKGRVKTSSGAPKVEKKLKKMEQNKTAATRYRQKKRVEQESLNSECSELEKKNRELSEKADSLSREIQYLRDLLEEMRTAKQRKSKR", "length": 339 }, "evidence": [ { "id": "FB:FBgn0000370", "url": "https://alliancegenome.org/gene/FB:FBgn0000370#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6P788-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-5", "gene_name": "Atf5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLATLGLELDRALLPASGLGWLVDYGKLPLAPAPLGPYEVLGGALEGGLPGGGEPLAGDGFSDWMTERVDFTALLPLEAPLPPGTLPPPSPAPPDLEAMASLLKKELEQMEDFFLDAPLLPPPSPPPPPPPAPSLPLPLPLPTFDLPQPPTLDTLDLLAVYCRSEAGPGDSGLTTLPVPQQPPPLAPLPSLSRPAPYPSPASTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELRERAESVEREIQYVKDLLIEVYKARSQRTRSA", "length": 281 }, "evidence": [ { "id": "HGNC:790", "url": "https://alliancegenome.org/gene/HGNC:790#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2637", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2637#orthology", "database": "AGR" }, { "id": "MGI:2141857", "url": "https://alliancegenome.org/gene/MGI:2141857#orthology", "database": "AGR" }, { "id": "RGD:628902", "url": "https://alliancegenome.org/gene/RGD:628902#orthology", "database": "AGR" }, { "id": "FB:FBgn0000370", "url": "https://alliancegenome.org/gene/FB:FBgn0000370#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ES19-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-4", "gene_name": "Atf4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEMSFLNSEVLAGDLMSPFDQSGLGAEESLGLLDDYLEVAKHFKPHGFSSDKAGSSEWLAMDGLVSASDTGKEDAFSGTDWMLEKMDLKEFDFDALFRMDDLETMPDELLATLDDTCDLFAPLVQETNKEPPQTVNPIGHLPESVIKVDQAAPFTFLQPLPCSPGFLSSTPDHSFSLELGSEVDISEGDRKPDSAAYITLTPQCVKEEDTPSDSDSGICMSPESYLGSPQHSPSTSRAPPDSLPSPGVPRGSRPKPYDPPGVSVTAKVKTEKLDKKLKKMEQNKTAATRYRQKKRAEQEALTGECKELEKKNEALKEKADSLAKEIQYLKDLIEEVRKARGKKRVP", "length": 347 }, "evidence": [ { "id": "FB:FBgn0000370", "url": "https://alliancegenome.org/gene/FB:FBgn0000370#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VID3-1", "protein_name": "Cryptocephal, isoform A", "gene_name": "crc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDATFHQTMESLQLPKELYWDLKMEPQSPTSVLGSDLFPLTDSNDTEWLYDDNFANGITLIGDDEALTLEEVASLQLLSDEEMVVEIFDLKDEECLLDQKATLNCIDYDSNSFQPNINVITQAIVPANKVQFGASSDAASLPSAADYQLNDGPSLILQQLTPPQSPPQFDAYKQAGDAQPKPVLVKAEQKVQCYTPDVTHAASATPFNFTNWVGGSEIARENQLVDDIVNMRAKELELSTNWQQLNEDCESQASSSLDSRSTGSGVCSSIADADEDWVPELISSSSSPAPTTIEQSASQPKKRTRTYGRGVEDRKIRKKEQNKNAATRYRQKKKLEMENVLGEEHVLSKENEQLRRTLQERHNEMRYLRQLIREFYHERKR", "length": 381 }, "evidence": [ { "id": "HGNC:790", "url": "https://alliancegenome.org/gene/HGNC:790#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2637", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2637#orthology", "database": "AGR" }, { "id": "MGI:2141857", "url": "https://alliancegenome.org/gene/MGI:2141857#orthology", "database": "AGR" }, { "id": "RGD:628902", "url": "https://alliancegenome.org/gene/RGD:628902#orthology", "database": "AGR" }, { "id": "FB:FBgn0000370", "url": "https://alliancegenome.org/gene/FB:FBgn0000370#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y2D1-1", "protein_name": "Cyclic AMP-dependent transcription factor ATF-5", "gene_name": "ATF5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLLATLGLELDRALLPASGLGWLVDYGKLPPAPAPLAPYEVLGGALEGGLPVGGEPLAGDGFSDWMTERVDFTALLPLEPPLPPGTLPQPSPTPPDLEAMASLLKKELEQMEDFFLDAPPLPPPSPPPLPPPPLPPAPSLPLSLPSFDLPQPPVLDTLDLLAIYCRNEAGQEEVGMPPLPPPQQPPPPSPPQPSRLAPYPHPATTRGDRKQKKRDQNKSAALRYRQRKRAEGEALEGECQGLEARNRELKERAESVEREIQYVKDLLIEVYKARSQRTRSC", "length": 282 }, "evidence": [ { "id": "HGNC:790", "url": "https://alliancegenome.org/gene/HGNC:790#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2637", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2637#orthology", "database": "AGR" }, { "id": "MGI:2141857", "url": "https://alliancegenome.org/gene/MGI:2141857#orthology", "database": "AGR" }, { "id": "RGD:628902", "url": "https://alliancegenome.org/gene/RGD:628902#orthology", "database": "AGR" }, { "id": "FB:FBgn0000370", "url": "https://alliancegenome.org/gene/FB:FBgn0000370#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P756", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P756", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P756", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P756", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P756", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P756", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756" } ], "pmid": "" }, { "name": "regulation of apoptotic process", "id": "GO:0042981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P756", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P756", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 15, "end_pos": 17, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P756", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P756" }, { "id": "PS50217", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BZIP", "eco_id": "ECO_0000259", "start_pos": 363, "end_pos": 426, "start_aa": "Gly", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 15, "end_pos": 17 }, { "start_pos": 262, "end_pos": 264 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z2H8-1", "uniprot_ac": "A0A8M6Z2H8", "uniprot_id": "A0A8M6Z2H8_DANRE", "mass": { "chemical_mass": 64565.0, "monoisotopic_mass": 64565.0 }, "refseq": { "ac": "XP_017207343", "name": "uncharacterized protein znf982 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207343" }, "gene_names": [ { "name": "znf982", "type": "recommended", "evidence": [ { "id": "A0A8M6Z2H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8" } ] }, { "name": "znf982", "type": "synonym", "evidence": [ { "id": "XP_017207343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207343" } ] } ], "protein_names": [ { "name": "Uncharacterized protein znf982 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z2H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein znf982 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017207343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207343" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017207343.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017207343", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207343" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6YTE0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YTE0#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0A8M6Z2H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8#function" }, { "database": "UniProtKB", "id": "A0AC58HP84", "url": "https://www.uniprot.org/uniprotkb/A0AC58HP84#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "znf982", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131120-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z2H8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z2H8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100331424", "url": "https://www.ncbi.nlm.nih.gov/gene/100331424", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100331424", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331424", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FIWHSSL", "url": "https://omabrowser.org/oma/group/FIWHSSL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YTE0", "url": "https://www.orthodb.org/?gene=A0A8M6YTE0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z2H8", "url": "https://www.orthodb.org/?gene=A0A8M6Z2H8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017207343", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207343", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YTE0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YTE0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YTE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YTE0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HP84", "url": "https://www.uniprot.org/uniprotkb/A0AC58HP84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HP84-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HP84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131120-1", "url": "https://zfin.org/ZDB-GENE-131120-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTSALTRSFSVESTELSSVPSSVKDEDSLLKNSEKMSDPEPCLIKQEDTEEEIALPPPVKDEDGLLKDSEKMSDPELYQIKQEETEEQIDLIVEEREVLSEDEEKHRVKGEIESHTKTEHNFLLKRPAIKAFTCTRCAKSFSYKCDLNHHIRIHNGEKPYKCSHCDKRFNRSGHLKTHERIHTGEKPYTCDQCGKSFVQISHLNQHMIIHNGEKTYTCDQCSKTFLIYSELKDHLKVHKNETKSHTCPDCGKNFIWHSSLKKHQKIHTGVREYMCSECEKTFITSGDLKQHQKIHTGEKPYMCSHCNKRFSHVKPLKVHERIHTGEKPYTCTQCGKSFRQSAHLNEHMLIHNGEKTHKCDHCGKTFLRPSELKKHLRVHTKEKPYSCSVCEKSFTQQSHLSQHQKIHTGVREYMCFACDKTYITAGDLKKHQRIHTGEKPFVCSDCNKSFRHSGHLTAHERIHTGEKPYACTQCEKTFRRPSNLNEHMMIHTGERPHKCEQCFQTFLRLAELKKHLRVHAKEKPQEVLHIDDIYLTENFTPYSQTSDFTVQYVD", "length": 554, "header": "tr|A0A8M6Z2H8-1|A0A8M6Z2H8_DANRE Isoform 1 of Uncharacterized protein znf982 isoform X1 OS=Danio rerio OX=7955 GN=znf982 PE=3 SV=3 CANONICAL=A0A8M6Z2H8-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YTE0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8/entry#A0A8M6YTE0-1", "sequence": { "sequence": "MSDPEPCLIKQEDTEEEIALPPPVKDEDGLLKDSEKMSDPELYQIKQEETEEQIDLIVEEREVLSEDEEKHRVKGEIESHTKTEHNFLLKRPAIKAFTCTRCAKSFSYKCDLNHHIRIHNGEKPYKCSHCDKRFNRSGHLKTHERIHTGEKPYTCDQCGKSFVQISHLNQHMIIHNGEKTYTCDQCSKTFLIYSELKDHLKVHKNETKSHTCPDCGKNFIWHSSLKKHQKIHTGVREYMCSECEKTFITSGDLKQHQKIHTGEKPYMCSHCNKRFSHVKPLKVHERIHTGEKPYTCTQCGKSFRQSAHLNEHMLIHNGEKTHKCDHCGKTFLRPSELKKHLRVHTKEKPYSCSVCEKSFTQQSHLSQHQKIHTGVREYMCFACDKTYITAGDLKKHQRIHTGEKPFVCSDCNKSFRHSGHLTAHERIHTGEKPYACTQCEKTFRRPSNLNEHMMIHTGERPHKCEQCFQTFLRLAELKKHLRVHAKEKPQEVLHIDDIYLTENFTPYSQTSDFTVQYVD", "length": 519, "header": "tr|A0A8M6YTE0-1|A0A8M6Z2H8_DANRE Computationally mapped isoform of Uncharacterized protein znf982 isoform X1 OS=Danio rerio OX=7955 GN=znf982 PE=3 SV=2 CANONICAL=A0A8M6Z2H8-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z2H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8/entry#A0A8M6Z2H8-1", "sequence": { "sequence": "MTSALTRSFSVESTELSSVPSSVKDEDSLLKNSEKMSDPEPCLIKQEDTEEEIALPPPVKDEDGLLKDSEKMSDPELYQIKQEETEEQIDLIVEEREVLSEDEEKHRVKGEIESHTKTEHNFLLKRPAIKAFTCTRCAKSFSYKCDLNHHIRIHNGEKPYKCSHCDKRFNRSGHLKTHERIHTGEKPYTCDQCGKSFVQISHLNQHMIIHNGEKTYTCDQCSKTFLIYSELKDHLKVHKNETKSHTCPDCGKNFIWHSSLKKHQKIHTGVREYMCSECEKTFITSGDLKQHQKIHTGEKPYMCSHCNKRFSHVKPLKVHERIHTGEKPYTCTQCGKSFRQSAHLNEHMLIHNGEKTHKCDHCGKTFLRPSELKKHLRVHTKEKPYSCSVCEKSFTQQSHLSQHQKIHTGVREYMCFACDKTYITAGDLKKHQRIHTGEKPFVCSDCNKSFRHSGHLTAHERIHTGEKPYACTQCEKTFRRPSNLNEHMMIHTGERPHKCEQCFQTFLRLAELKKHLRVHAKEKPQEVLHIDDIYLTENFTPYSQTSDFTVQYVD", "length": 554, "header": "tr|A0A8M6Z2H8-1|A0A8M6Z2H8_DANRE Isoform 1 of Uncharacterized protein znf982 isoform X1 OS=Danio rerio OX=7955 GN=znf982 PE=3 SV=3 CANONICAL=A0A8M6Z2H8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HP84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8/entry#A0AC58HP84-1", "sequence": { "sequence": "MTSALTRSFSVESTELSSVPSSVKDEDSLLKNSEKMSDPEPCLIKQEDTEEEIDLMVKDESEVLSEDEEKHQVKSEIKTRIKMEHRSVTERTACTQCGKSFSHKYDLKPHMRIHTGEKPFTCTHCEKSFRQSSSLNRHLLIHTGEKPHKCDRCGKTFLISSDLKKHLRVHTNEKPFSCSVCGKSFTQQSSLGIHQKIHTGVREHMCFECEKSFITAGNLKRHQMIHTGEKPYKCSHCEKRFSQLDDLKRHERIHTGERPFTCTECGKSFRQSSSFNRHTMFHSGEKTHKCE", "length": 291, "header": "tr|A0AC58HP84-1|A0AC58HP84_DANRE Computationally mapped isoform of Uncharacterized protein znf982 isoform X4 OS=Danio rerio OX=7955 GN=znf982 PE=3 SV=1 CANONICAL=A0A8M6Z2H8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100331424", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331424", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AH96-1", "protein_name": "Zinc finger protein 707-like 1", "gene_name": "Zfp707l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGCCYGGQHKCHLGWTNFYPPAHQRRCLCYLLDALMKPVIQVPVTFREVAVYFCREEWECLSFSQRTLYRDVMLENFRNLNELGCCGRKPSLISRLEQWDEPWVDKWDSSELERQKSVCPGGRKASAPEKTHSRTGAKSRTTLRKNVLTSGKAHFTRATSGRKLDNKSEALQNQTCGKSRRRQPGLKEQGKSAAEGHPFICGICGKALSCHSRLAAHQTVHTGTRSFECFECGQTFRWVSNLLRHQRNHTSEKPFCCEVCGQAFSLKDRLAQHQKIHTEHRPYVCSDCGKAFKQKSNLLRHKLVHTGERPFYCDNCGKTFRTKENLNHHQRIHSGEKPYTCGECGKAFRWPKGFSIHQRLHLTKKFYECEECGKGFRHLGFFTRHQRTHGRGEV", "length": 395 }, "evidence": [ { "id": "HGNC:27815", "url": "https://alliancegenome.org/gene/HGNC:27815#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3B221-1", "protein_name": "Uncharacterized protein si:cabz01032474.1", "gene_name": "si:cabz01032474.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFIKEESEDIRIVEVFTLKHEDPEEETGLMELKEETQELNEMEEVDSQHDLRTDEESTEGVQETESNFKCCHCGKCFSNEQNLEIHMRNQNGEKPFICKKCGMGFSQNRKLHVHMRIHTGEKRFPCPQCGKCFTVKYSLRVHMRVHTGENPYTCPECGKGFKQKNSFNYHMRTHKGLKIVETDSVEVDI", "length": 190 }, "evidence": [ { "id": "HGNC:27815", "url": "https://alliancegenome.org/gene/HGNC:27815#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PGY2-1", "protein_name": "Zinc finger protein isoform X1", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDLQEQTDLMMLKEETHQQNEVEEKHQDIPTDEKPTLTKKTSSHRRHLNYKSECNFSCKQSRKSFSQKPNLDVYTRVHNREKHYTCKQCGKSFPKIHFLKAHMRIHIGERSYTCQQCGKIFHYARNLAAHMRIHTGEKPYSCPQCGKSFKQNNNLEVHMRTHTGERSFTCTQCGKSFAKKQNLKIHMRIHTGEKPFTCTECGKSFRCKSTFNIHKRTHTGEKPYRCTECGKSFPNKSTFNNHMRIHTGEKPYRCTECGKSFIRKSTLNYHVRTHTGEKLFACVQCGKSFTTKLSLMNHMNGHTGTIVFTCDQCGKSLTRKDSIKRHMKTHSGERFRCSECGKDFKHERSLRAHMKLHNAEQSPQHLGLVHTNTGIFKTAAFSCSLAVHSSEVYL", "length": 415 }, "evidence": [ { "id": "HGNC:27815", "url": "https://alliancegenome.org/gene/HGNC:27815#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A8V7-1", "protein_name": "Zinc finger protein 981", "gene_name": "Zfp981", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSASLVNPPQDLLTFNDVALNFSLEEWECLNFAQRTLYMEVMLENYNNVLFVENQCICGKNESFLDQDIQHIVNEHGHIRKKSSKCNELSNVIHESSESTPYNTNQRDATFQFSNLKRHKTGTTKEVCTYKDCVNCLKGSSIISLNQGTHIEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDSLQSQQRKPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCSECDKCFTDKGYLRVHQRIHTGEKPYKCSECDKCFTDKGYLRVHQRIHTGEKPYKCSECDKCFTQPSHLSFHRRIHSGEKPYKCSECDKCFTDKFILGKHQRIHTGKKPYKCSECDKCFTDKGYLRVHQRIHTGEKPYKCSECDKCFTQQCHLSIHQKIHSGEKPYKCNECDKCFT", "length": 445 }, "evidence": [ { "id": "RGD:1565622", "url": "https://alliancegenome.org/gene/RGD:1565622#orthology", "database": "AGR" }, { "id": "RGD:1561413", "url": "https://alliancegenome.org/gene/RGD:1561413#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWF2-1", "protein_name": "Reduced expression 2", "gene_name": "Rex2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVLEQDTQHIVNEHGHNRKKSSKCNELRNVIHESSESTPYNTNHRDATLQSSNLKRHKTGTTKGVCTYKDCVNCLKGSSIISLNQGTHIEKKEHNRNKNLDEVLVSRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQTSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQPSHLSIHRRIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCSECDKCFTEKFTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTKPSHLSIHRRIHSGEKPYKCSECDKCFTQPSPLSIHRRIHSGEKPYKCSECDKCFTDKGSLRVHQRIHIGEKPYKCSECDKCFTQPSHLSIHCRIHSGEKPYKCSECDKCFTHKGSLRVHHRIHAGEKPYKCSECDKCFTEKNGLRRHQRIHTGEKPYKCSECDKCFTRKSHLSIHQRIHTGEKLYKCSECDKCFTQQCHLSIHQKIHSGENLTNAMNATNALVTNTV", "length": 685 }, "evidence": [ { "id": "RGD:1565622", "url": "https://alliancegenome.org/gene/RGD:1565622#orthology", "database": "AGR" }, { "id": "RGD:1561413", "url": "https://alliancegenome.org/gene/RGD:1561413#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z445-1", "protein_name": "Zinc finger protein 707", "gene_name": "Zfp707", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRRLAAAAALGEARRERCFRRGSALPERANGDAPPVPVTFRDVAVYFCREEWECLSPSQRTLYRNVMLENFRNLNELGCCSRRPGLITRLEQWDEPWVDDWDRSEFPDGQKSFCPGSRKVAHSRIGAGRGAALRKSALTSGKVRLPRATSGRRMDKREAFQNRICGKSHRKQPDLKEQGQSGPEGQPFICGICGKALSCHSRLAAHQTVHTGTRSFECLECGRTFRWASNLLRHQRNHTSEKPFCCELCGQAFSLKDRLAQHRKIHTEHRPYECGDCGKAFKQKSNLLRHKLVHTGEKPFYCDTCGKAFRTKENLSHHQRIHSGEKPYTCGECGKAFRWPKGFSIHQRLHLTKKFYQCEQCGKGFRHLGFFTRHQRTHGRGEV", "length": 384 }, "evidence": [ { "id": "HGNC:27815", "url": "https://alliancegenome.org/gene/HGNC:27815#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LZG2-1", "protein_name": "Zinc finger protein 534 like 2", "gene_name": "Zfp534l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMALGNTLQGFLTFKDVVPEFTLEEWESLTYAQRALYMDVILETYNNLLSVENHLIHGKHGEVLEQDTECIVHELVNIQEKFCKWDEISKMTLESTQSTPYKTHLRDPSLRSSNLKRHKAGKTREVYKYKDCVQFSNECAIIGVNSGIHIENKEHKNTEFDNDFVYKHKLMLKEDINGKNLHQDGECEKCFTKTRKLHFYQRIHTGEKPYKCSECDKCFVSNLSLIIHQRIHTGEKPYKCSQCDKYFARESCLRRHQRSHSGEKPYKCSQCDKYFAQKYYLSIHQRIHTGEKRYKCSQCDKYFSQESCLRRHQRIHTGEKPYKCSQCDKYFSQKFHLSIHQRIHTGEKPYKCSECDKCFTEKRTLRNHMRIHTGEKPYKCSECDKCFGRKGSLRIHQRIHTGEKPYKCGECDKCFGQQSHRSIHQRIHTGEKPYKCSQCDKHFTQESCLRRHQRIHTGDKPYKCCQCDKYFSQEFYLSIHQRIHTGEKPYKCSECDKCFTEKGTLRNHMRLHTGEKPYKCSECDKSFVQQSHLTVHQRSHTGEKPYKCSQCDKCFARESCRRRHQRIHTGDKPYKCNQCAKYFAGESYLSIH", "length": 593 }, "evidence": [ { "id": "RGD:1565622", "url": "https://alliancegenome.org/gene/RGD:1565622#orthology", "database": "AGR" }, { "id": "RGD:1561413", "url": "https://alliancegenome.org/gene/RGD:1561413#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96C28-1", "protein_name": "Zinc finger protein 707", "gene_name": "ZNF707", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDMAQEPVTFRDVAIYFSREEWACLEPSQRALYRDVMLDNFSSVAALGFCSPRPDLVSRLEQWEEPWVEDRERPEFQAVQRGPRPGARKSADPKRPCDHPAWAHKKTHVRRERAREGSSFRKGFRLDTDDGQLPRAAPERTDAKPTAFPCQVLTQRCGRRPGRRERRKQRAVELSFICGTCGKALSCHSRLLAHQTVHTGTKAFECPECGQTFRWASNLQRHQKNHTREKPFCCEACGQAFSLKDRLAQHRKVHTEHRPYSCGDCGKAFKQKSNLLRHQLVHTGERPFYCADCGKAFRTKENLSHHQRVHSGEKPYTCAECGKSFRWPKGFSIHRRLHLTKRFYECGHCGKGFRHLGFFTRHQRTHRHGEV", "length": 371 }, "evidence": [ { "id": "HGNC:27815", "url": "https://alliancegenome.org/gene/HGNC:27815#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 447, "end_pos": 449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z2H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H8" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 159, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 240, "end_pos": 242 }, { "start_pos": 447, "end_pos": 449 }, { "start_pos": 538, "end_pos": 540 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P7I2-1", "uniprot_ac": "A0A8M9P7I2", "uniprot_id": "A0A8M9P7I2_DANRE", "mass": { "chemical_mass": 101423.0, "monoisotopic_mass": 101423.0 }, "refseq": { "ac": "XP_021322188", "name": "SID1 transmembrane family member 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322188" }, "gene_names": [ { "name": "sidt2", "type": "recommended", "evidence": [ { "id": "A0A8M9P7I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2" } ] }, { "name": "sidt2", "type": "synonym", "evidence": [ { "id": "XP_021322188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322188" } ] } ], "protein_names": [ { "name": "SID1 transmembrane family member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322188" }, { "id": "A0A8M9P7I2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322188" } ] } ], "disease": [ { "disease_id": "DOID:0080208", "recommended_name": { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol." }, "synonyms": [ { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "nonalcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "non-alcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "NAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-related steatotic liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MASLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic-associated fatty liver disease", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "NAFLD2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "fatty liver disease, nonalcoholic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "liver disease, alcoholic, susceptibility to, 1", "description": "" }, { "id": "MIM:613282", "resource": "MIM", "url": "https://www.omim.org/entry/613282", "name": "Non-alcoholic fatty liver disease 1", "description": "Non-alcoholic fatty liver disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sidt2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-7356", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7356", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P7I2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P7I2", "database": "AlphaFoldDB", "categories": [] }, { "id": "796833", "url": "https://www.ncbi.nlm.nih.gov/gene/796833", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:796833", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796833", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P7I2", "url": "https://www.orthodb.org/?gene=A0A8M9P7I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12185", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12185", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12185:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12185:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13965", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13965", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322188", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9NYU9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9NYU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P7I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCM2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIX3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLX3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLX3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T8Z3", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8Z3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T8Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8Z3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HE38", "url": "https://www.uniprot.org/uniprotkb/A0AC58HE38", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HE38-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HE38-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-7356", "url": "https://zfin.org/ZDB-GENE-030131-7356", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTSHRRAVSTQQRDGERVRTDAGWRTDRIYIGSTSVSVFSQADAGSRMLWWCCGSVLRLVLMLVFLFCCPAVSSTNDVVPAQFDVTYFDTVTSEKQTIYSYNHTVSRNKTEGVRVSVELQSESALSPILFVVRQKQAVLSFQVPLILRGLYQRKYQYTQVSRTLCQPPTKAMSETQFFYVDVSTLASSGISYQLRVSRVDSFTLQTDKKFSFNATPSQPQFFKYVFPEGVDTVIVKVNSQKNFPCSVMSIQDIQCPVYDLDNNVAFIGMYQTMTTRSAITVQRKDFPSNSFYVVVVVKTEDEACGGPLRFYPLLPDELLDAGNRSKTLDVIVSPAINSEVYVMGMLFCLGIFLSFYLLTFLVACLENKRMNRKREGLLNPDTSPAETASLLGKAPVSPYEYGSFADNGSTLSSEAVTDSLTSTDGNYGYMGSETFKRRLVTAHHVAIRFERSLESISRSRQESLSSVEEDDYDTLADIDSDKNIVRTKKFLCVSDLARKDKRILSKKYQIYFWNIATIAVFYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGALSSFNNILSNLGYVLLGLLFLLIVLQRDILHNRALERNDNTALECGIPKHFGLYYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAAVIFFSVLGVVFGKGNMAFWIVFSVIHILATMLLSTQLYYMGRWRLDSGIMRRMLYVIYTDCIRQCSGPMYIDRMVLLVMGNIVNWSLAAYGLINRPNDFASYLLAIAICNLLLYFAFYIIMKLRSGERIQCLALVCVLFTAVVWGFALFFFFQGLSTWQKTPAESREHNRECILLSFFDDHDIWHFLSSIAMFGSFLVLLTMDDDLDSVQRDKIYVF", "length": 894, "header": "tr|A0A8M9P7I2-1|A0A8M9P7I2_DANRE Isoform 1 of SID1 transmembrane family member 2 isoform X1 OS=Danio rerio OX=7955 GN=sidt2 PE=3 SV=1 CANONICAL=A0A8M9P7I2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9NYU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2/entry#A0A8M9NYU9-1", "sequence": { "sequence": "MLWWCCGSVLRLVLMLVFLFCCPAVSSTNDVVPAQFDVTYFDTVTSEKQTIYSYNHTVSRNKTEGVRVSVELQSESALSPILFVVRQKQAVLSFQVPLILRGLYQRKYQYTQVSRTLCQPPTKAMSETQFFYVDVSTLASSGISYQLRVSRVDSFTLQTDKKFSFNATPSQPQFFKYVFPEGVDTVIVKVNSQKNFPCSVMSIQDIQCPVYDLDNNVAFIGMYQTMTTRSAITVQRKDFPSNSFYVVVVVKTEDEACGGPLRFYPLLPDELLDAGNRSKTLDVIVSPAINSEVYVMGMLFCLGIFLSFYLLTFLVACLENKRMNRKREGLLNPDTSPAETASLLGKAPVSPYEYGSFADNGSTLSSEAVTDSLTSTDGNYGYMGSETFKRRLVTAHHVAIRFERSLESISRSRQESLSSVEEDDYDTLADIDSDKNIVRTKKFLCVSDLARKDKRILSKKYQIYFWNIATIAVFYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGALSSFNNILSNLGYVLLGLLFLLIVLQRDILHNRALERNDNTALECGIPKHFGLYYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAAVIFFSVLGVVFGKGNMAFWIVFSVIHILATMLLSTQLYYMGRWRLDSGIMRRMLYVIYTDCIRQCSGPMYIDRMVLLVMGNIVNWSLAAYGLINRPNDFASYLLAIAICNLLLYFAFYIIMKLRSGERIQCLALVCVLFTAVVWGFALFFFFQGLSTWQKTPAESREHNRECILLSFFDDHDIWHFLSSIAMFGSFLVLLTMDDDLDSVQRDKIYVF", "length": 847, "header": "tr|A0A8M9NYU9-1|A0A8M9P7I2_DANRE Computationally mapped isoform of SID1 transmembrane family member 2 isoform X1 OS=Danio rerio OX=7955 GN=sidt2 PE=3 SV=1 CANONICAL=A0A8M9P7I2-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P7I2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2/entry#A0A8M9P7I2-1", "sequence": { "sequence": "MTSHRRAVSTQQRDGERVRTDAGWRTDRIYIGSTSVSVFSQADAGSRMLWWCCGSVLRLVLMLVFLFCCPAVSSTNDVVPAQFDVTYFDTVTSEKQTIYSYNHTVSRNKTEGVRVSVELQSESALSPILFVVRQKQAVLSFQVPLILRGLYQRKYQYTQVSRTLCQPPTKAMSETQFFYVDVSTLASSGISYQLRVSRVDSFTLQTDKKFSFNATPSQPQFFKYVFPEGVDTVIVKVNSQKNFPCSVMSIQDIQCPVYDLDNNVAFIGMYQTMTTRSAITVQRKDFPSNSFYVVVVVKTEDEACGGPLRFYPLLPDELLDAGNRSKTLDVIVSPAINSEVYVMGMLFCLGIFLSFYLLTFLVACLENKRMNRKREGLLNPDTSPAETASLLGKAPVSPYEYGSFADNGSTLSSEAVTDSLTSTDGNYGYMGSETFKRRLVTAHHVAIRFERSLESISRSRQESLSSVEEDDYDTLADIDSDKNIVRTKKFLCVSDLARKDKRILSKKYQIYFWNIATIAVFYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGALSSFNNILSNLGYVLLGLLFLLIVLQRDILHNRALERNDNTALECGIPKHFGLYYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAAVIFFSVLGVVFGKGNMAFWIVFSVIHILATMLLSTQLYYMGRWRLDSGIMRRMLYVIYTDCIRQCSGPMYIDRMVLLVMGNIVNWSLAAYGLINRPNDFASYLLAIAICNLLLYFAFYIIMKLRSGERIQCLALVCVLFTAVVWGFALFFFFQGLSTWQKTPAESREHNRECILLSFFDDHDIWHFLSSIAMFGSFLVLLTMDDDLDSVQRDKIYVF", "length": 894, "header": "tr|A0A8M9P7I2-1|A0A8M9P7I2_DANRE Isoform 1 of SID1 transmembrane family member 2 isoform X1 OS=Danio rerio OX=7955 GN=sidt2 PE=3 SV=1 CANONICAL=A0A8M9P7I2-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PCM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2/entry#A0A8M9PCM2-1", "sequence": { "sequence": "MTSHRRAVSTQQRDGERVRTDAGWRTDRIYIGSTSVSVFSQADAGSRMLWWCCGSVLRLVLMLVFLFCCPAVSSTNDVVPAQFDVTYFDTVTSEKQTIYSYNHTVSRNKTEGVRVSVELQSESALSPILFVVRQKQAVLSFQVPLILRGLYQRKYQYTQVSRTLCQPPTKAMSETQFFYVDVSTLASSGISYQLRVSRVDSFTLQTDKKFSFNATPSQPQFFKYVFPEGVDTVIVKVNSQKNFPCSVMSIQDIQCPVYDLDNNVAFIGMYQTMTTRSAITVQRKDFPSNSFYVVVVVKTEDEACGGPLRFYPLLPDELLDAGNRSKTLDVIVSPAINSEVYVMGMLFCLGIFLSFYLLTFLVACLENKRMNRKREGLLNPDTSPAETGKAPVSPYEYGSFADNGSTLSSEAVTDSLTSTDGNYGYMGSETFKRRLVTAHHVAIRFERSLESISRSRQESLSSVEEDDYDTLADIDSDKNIVRTKKFLCVSDLARKDKRILSKKYQIYFWNIATIAVFYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGALSSFNNILSNLGYVLLGLLFLLIVLQRDILHNRALERNDNTALECGIPKHFGLYYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAAVIFFSVLGVVFGKGNMAFWIVFSVIHILATMLLSTQLYYMGRWRLDSGIMRRMLYVIYTDCIRQCSGPMYIDRMVLLVMGNIVNWSLAAYGLINRPNDFASYLLAIAICNLLLYFAFYIIMKLRSGERIQCLALVCVLFTAVVWGFALFFFFQGLSTWQKTPAESREHNRECILLSFFDDHDIWHFLSSIAMFGSFLVLLTMDDDLDSVQRDKIYVF", "length": 890, "header": "tr|A0A8M9PCM2-1|A0A8M9PCM2_DANRE Computationally mapped isoform of SID1 transmembrane family member 2 isoform X2 OS=Danio rerio OX=7955 GN=sidt2 PE=3 SV=1 CANONICAL=A0A8M9P7I2-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PIX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2/entry#A0A8M9PIX3-1", "sequence": { "sequence": "MTSHRRAVSTQQRDGERVRTDAGWRTDRIYIGSTSVSVFSQADAGSRMLWWCCGSVLRLVLMLVFLFCCPAVSSTNDVVPAQFDVTYFDTVTSEKQTIYSYNHTVSRNKTEGVRVSVELQSESALSPILFVVRQKQAVLSFQVPLILRGLYQRKYQYTQVSRTLCQPPTKAMSETQFFYVDVSTLASSGISYQLRVSRVDSFTLQTDKKFSFNATPSQPQFFKYVFPEGVDTVIVKVNSQKNFPCSVMSIQDIQCPVYDLDNNVAFIGMYQTMTTRSAITVQRKDFPSNSFYVVVVVKTEDEACGGPLRFYPLLPDELLDAGNRSKTLDVIVSPAINSEVYVMGMLFCLGIFLSFYLLTFLVACLENKRMNRKREGLLNPDTSPAETGKAPVSPYEYGSFADNGSTLSSEAVTDSLTSTDGNYGYMERSLESISRSRQESLSSVEEDDYDTLADIDSDKNIVRTKKFLCVSDLARKDKRILSKKYQIYFWNIATIAVFYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGALSSFNNILSNLGYVLLGLLFLLIVLQRDILHNRALERNDNTALECGIPKHFGLYYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAAVIFFSVLGVVFGKGNMAFWIVFSVIHILATMLLSTQLYYMGRWRLDSGIMRRMLYVIYTDCIRQCSGPMYIDRMVLLVMGNIVNWSLAAYGLINRPNDFASYLLAIAICNLLLYFAFYIIMKLRSGERIQCLALVCVLFTAVVWGFALFFFFQGLSTWQKTPAESREHNRECILLSFFDDHDIWHFLSSIAMFGSFLVLLTMDDDLDSVQRDKIYVF", "length": 871, "header": "tr|A0A8M9PIX3-1|A0A8M9PIX3_DANRE Computationally mapped isoform of SID1 transmembrane family member 2 isoform X4 OS=Danio rerio OX=7955 GN=sidt2 PE=3 SV=1 CANONICAL=A0A8M9P7I2-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PLX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2/entry#A0A8M9PLX3-1", "sequence": { "sequence": "MTSHRRAVSTQQRDGERVRTDAGWRTDRIYIGSTSVSVFSQADAGSRMLWWCCGSVLRLVLMLVFLFCCPAVSSTNDVVPAQFDVTYFDTVTSEKQTIYSYNHTVSRNKTEGVRVSVELQSESALSPILFVVRQKQAVLSFQVPLILRGLYQRKYQYTQVSRTLCQPPTKAMSETQFFYVDVSTLASSGISYQLRVSRVDSFTLQTDKKFSFNATPSQPQFFKYVFPEGVDTVIVKVNSQKNFPCSVMSIQDIQCPVYDLDNNVAFIGMYQTMTTRSAITVQRKDFPSNSFYVVVVVKTEDEACGGPLRFYPLLPDELLDAGNRSKTLDVIVSPAINSEVYVMGMLFCLGIFLSFYLLTFLVACLENKRMNRKREGLLNPDTSPAETASLLGKAPVSPYEYGSFADNGSTLSSEAVTDSLTSTDGNYGYMERSLESISRSRQESLSSVEEDDYDTLADIDSDKNIVRTKKFLCVSDLARKDKRILSKKYQIYFWNIATIAVFYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGALSSFNNILSNLGYVLLGLLFLLIVLQRDILHNRALERNDNTALECGIPKHFGLYYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAAVIFFSVLGVVFGKGNMAFWIVFSVIHILATMLLSTQLYYMGRWRLDSGIMRRMLYVIYTDCIRQCSGPMYIDRMVLLVMGNIVNWSLAAYGLINRPNDFASYLLAIAICNLLLYFAFYIIMKLRSGERIQCLALVCVLFTAVVWGFALFFFFQGLSTWQKTPAESREHNRECILLSFFDDHDIWHFLSSIAMFGSFLVLLTMDDDLDSVQRDKIYVF", "length": 875, "header": "tr|A0A8M9PLX3-1|A0A8M9PLX3_DANRE Computationally mapped isoform of SID1 transmembrane family member 2 isoform X3 OS=Danio rerio OX=7955 GN=sidt2 PE=3 SV=1 CANONICAL=A0A8M9P7I2-1" }, "locus": {} }, { "isoform_ac": "A0AB32T8Z3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2/entry#A0AB32T8Z3-1", "sequence": { "sequence": "MLWWCCGSVLRLVLMLVFLFCCPAVSSTNDVVPAQFDVTYFDTVTSEKQTIYSYNHTVSRNKTEGVRVSVELQSESALSPILFVVRQKQAVLSFQVPLILRGLYQRKYQYTQVSRTLCQPPTKAMSETQFFYVDVSTLASSGISYQLRVSRVDSFTLQTDKKFSFNATPSQPQFFKYVFPEGVDTVIVKVNSQKNFPCSVMSIQDIQCPVYDLDNNVAFIGMYQTMTTRSAITVQRKDFPSNSFYVVVVVKTEDEACGGPLRFYPLLPDELLDAGNRSKTLDVIVSPAINSEVYVMGMLFCLGIFLSFYLLTFLVACLENKRMNRKREGLLNPDTSPAETGKAPVSPYEYGSFADNGSTLSSEAVTDSLTSTDGNYGYMERSLESISRSRQESLSSVEEDDYDTLADIDSDKNIVRTKKFLCVSDLARKDKRILSKKYQIYFWNIATIAVFYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGALSSFNNILSNLGYVLLGLLFLLIVLQRDILHNRALERNDNTALECGIPKHFGLYYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAAVIFFSVLGVVFGKGNMAFWIVFSVIHILATMLLSTQLYYMGRWRLDSGIMRRMLYVIYTDCIRQCSGPMYIDRMVLLVMGNIVNWSLAAYGLINRPNDFASYLLAIAICNLLLYFAFYIIMKLRSGERIQCLALVCVLFTAVVWGFALFFFFQGLSTWQKTPAESREHNRECILLSFFDDHDIWHFLSSIAMFGSFLVLLTMDDDLDSVQRDKIYVF", "length": 824, "header": "tr|A0AB32T8Z3-1|A0A8M9P7I2_DANRE Computationally mapped isoform of SID1 transmembrane family member 2 isoform X1 OS=Danio rerio OX=7955 GN=sidt2 PE=3 SV=1 CANONICAL=A0A8M9P7I2-1" }, "locus": {} }, { "isoform_ac": "A0AC58HE38-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2/entry#A0AC58HE38-1", "sequence": { "sequence": "MLWWCCGSVLRLVLMLVFLFCCPAVSSTNDVVPAQFDVTYFDTVTSEKQTIYSYNHTVSRNKTEGVRVSVELQSESALSPILFVVRQKQAVLSFQVPLILRGLYQRKYQYTQVSRTLCQPPTKAMSETQFFYVDVSTLASSGISYQLRVSRVDSFTLQTDKKFSFNATPSQPQFFKYVFPEGVDTVIVKVNSQKNFPCSVMSIQDIQCPVYDLDNNVAFIGMYQTMTTRSAITVQRKDFPSNSFYVVVVVKTEDEACGGPLRFYPLLPDELLDAGNRSKTLDVIVSPAINSEVYVMGMLFCLGIFLSFYLLTFLVACLENKRMNRKREGLLNPDTSPAETGKAPVSPYEYGSFADNGSTLSSEAVTDSLTSTDGNYGYMGSETFKRRLVTAHHVAIRFERSLESISRSRQESLSSVEEDDYDTLADIDSDKNIVRTKKFLCVSDLARKDKRILSKKYQIYFWNIATIAVFYALPVIQLVITYQTVVNVTGNQDICYYNFLCAHPLGALSSFNNILSNLGYVLLGLLFLLIVLQRDILHNRALERNDNTALECGIPKHFGLYYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAAVIFFSVLGVVFGKGNMAFWIVFSVIHILATMLLSTQLYYMGRWRLDSGIMRRMLYVIYTDCIRQCSGPMYIDRMVLLVMGNIVNWSLAAYGLINRPNDFASYLLAIAICNLLLYFAFYIIMKLRSGERIQCLALVCVLFTAVVWGFALFFFFQGLSTWQKTPAESREHNRECILLSFFDDHDIWHFLSSIAMFGSFLVLLTMDDDLDSVQRDKIYVF", "length": 843, "header": "tr|A0AC58HE38-1|A0AC58HE38_DANRE Computationally mapped isoform of SID1 transmembrane family member 2 isoform X6 OS=Danio rerio OX=7955 GN=sidt2 PE=3 SV=1 CANONICAL=A0A8M9P7I2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 215, "start_aa": "Thr", "end_pos": 215, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr215", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:796833", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796833", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZEH5-1", "protein_name": "SID1 transmembrane family member 2", "gene_name": "Sidt2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIAWRLPLCVLLVAAVESHLGALGPKNVSQKDAEFERTYADDVNSELVNIYTFNHTVTRNRTEGVRVSVNVLNKQKGAPLLFVVRQKEAVVSFQVPLILRGLYQRKYLYQKVERTLCQPPTKNESEIQFFYVDVSTLSPVNTTYQLRVNRVDNFVLRTGELFTFNTTAAQPQYFKYEFPDGVDSVIVKVTSKKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDFPSNSFYVVVVVKTEDQACGGSLPFYPFVEDEPVDQGHRQKTLSVLVSQAVTSEAYVGGMLFCLGIFLSFYLLTVLLACWENWRQRKKTLLVAIDRACPESGHPRVLADSFPGSAPYEGYNYGSFENGSGSTDGLVESTGSGDLSYSYQDRSFDPVGARPRLDSMSSVEEDDYDTLTDIDSDKNVIRTKQYLCVADLARKDKRVLRKKYQIYFWNIATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILLGLLFLLIILQREINHNRALLRNDLYALECGIPKHFGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAIVIFFSVLGVVFGKGNTAFWIVFSVIHIISTLLLSTQLYYMGRWKLDSGIFRRILHVLYTDCIRQCSGPLYTDRMVLLVMGNIINWSLAAYGLIMRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIVCTSVVWGFALFFFFQGLSTWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLVLLTLDDDLDTVQRDKIYVF", "length": 832 }, "evidence": [ { "id": "RGD:1308311", "url": "https://alliancegenome.org/gene/RGD:1308311#orthology", "database": "AGR" }, { "id": "HGNC:24272", "url": "https://alliancegenome.org/gene/HGNC:24272#orthology", "database": "AGR" }, { "id": "MGI:2446134", "url": "https://alliancegenome.org/gene/MGI:2446134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7356", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7356#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CIF6-1", "protein_name": "SID1 transmembrane family member 2", "gene_name": "Sidt2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIAWRLPLCVLLVASVESHLGALGPKNVSQKDAEFERTYADDVNSELVNIYTFNHTVTRNRTEGVRVSVNVLNKQKGAPLLFVVRQKEAVVSFQVPLILRGLYQRKYLYQKVERTLCQPPTKNESEIQFFYVDVSTLSPVNTTYQLRVNRVDNFVLRTGELFTFNTTAAQPQYFKYEFPDGVDSVIVKVTSKKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDFPSNSFYVVVVVKTEDQACGGSLPFYPFVEDEPVDQGHRQKTLSVLVSQAVTSEAYVGGMLFCLGIFLSFYLLTVLLACWENWRQRKKTLLLAIDRACPESGHARVLADSFPGSAPYEGYNYGSFENGSGSTDGLVESAGSGDLSYSYQDRSFDAVGPRPRLDSMSSVEEDDYDTLTDIDSDKNVIRTKQYLCVADLARKDKRVLRKKYQIYFWNIATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILLGLLFLLIILQREINHNRALLRNDLYALECGIPKHFGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAIVIFFSVLGVVFGKGNTAFWIVFSVIHIISTLLLSTQLYYMGRWKLDSGIFRRILHVLYTDCIRQCSGPLYTDRMVLLVMGNIINWSLAAYGLIMRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIVCTSVVWGFALFFFFQGLSTWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLVLLTLDDDLDTVQRDKIYVF", "length": 832 }, "evidence": [ { "id": "RGD:1308311", "url": "https://alliancegenome.org/gene/RGD:1308311#orthology", "database": "AGR" }, { "id": "HGNC:24272", "url": "https://alliancegenome.org/gene/HGNC:24272#orthology", "database": "AGR" }, { "id": "MGI:2446134", "url": "https://alliancegenome.org/gene/MGI:2446134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7356", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7356#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NBJ9-1", "protein_name": "SID1 transmembrane family member 2", "gene_name": "SIDT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFALGLPFLVLLVASVESHLGVLGPKNVSQKDAEFERTYVDEVNSELVNIYTFNHTVTRNRTEGVRVSVNVLNKQKGAPLLFVVRQKEAVVSFQVPLILRGMFQRKYLYQKVERTLCQPPTKNESEIQFFYVDVSTLSPVNTTYQLRVSRMDDFVLRTGEQFSFNTTAAQPQYFKYEFPEGVDSVIVKVTSNKAFPCSVISIQDVLCPVYDLDNNVAFIGMYQTMTKKAAITVQRKDFPSNSFYVVVVVKTEDQACGGSLPFYPFAEDEPVDQGHRQKTLSVLVSQAVTSEAYVSGMLFCLGIFLSFYLLTVLLACWENWRQKKKTLLVAIDRACPESGHPRVLADSFPGSSPYEGYNYGSFENVSGSTDGLVDSAGTGDLSYGYQGRSFEPVGTRPRVDSMSSVEEDDYDTLTDIDSDKNVIRTKQYLYVADLARKDKRVLRKKYQIYFWNIATIAVFYALPVVQLVITYQTVVNVTGNQDICYYNFLCAHPLGNLSAFNNILSNLGYILLGLLFLLIILQREINHNRALLRNDLCALECGIPKHFGLFYAMGTALMMEGLLSACYHVCPNYTNFQFDTSFMYMIAGLCMLKLYQKRHPDINASAYSAYACLAIVIFFSVLGVVFGKGNTAFWIVFSIIHIIATLLLSTQLYYMGRWKLDSGIFRRILHVLYTDCIRQCSGPLYVDRMVLLVMGNVINWSLAAYGLIMRPNDFASYLLAIGICNLLLYFAFYIIMKLRSGERIKLIPLLCIVCTSVVWGFALFFFFQGLSTWQKTPAESREHNRDCILLDFFDDHDIWHFLSSIAMFGSFLVLLTLDDDLDTVQRDKIYVF", "length": 832 }, "evidence": [ { "id": "RGD:1308311", "url": "https://alliancegenome.org/gene/RGD:1308311#orthology", "database": "AGR" }, { "id": "HGNC:24272", "url": "https://alliancegenome.org/gene/HGNC:24272#orthology", "database": "AGR" }, { "id": "MGI:2446134", "url": "https://alliancegenome.org/gene/MGI:2446134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7356", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7356#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2" } ], "pmid": "" }, { "name": "lysosome", "id": "GO:0005764", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005764", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "double-stranded RNA binding", "id": "GO:0003725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003725", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2" } ], "pmid": "" }, { "name": "RNA transmembrane transporter activity", "id": "GO:0051033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051033", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "RNA transport", "id": "GO:0050658", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050658", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P7I2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7I2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 538, "end_pos": 540, "annotation": "n_glycosylation_sequon" }, { "start_pos": 634, "end_pos": 636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" }, { "start_pos": 761, "end_pos": 763, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 215 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 108, "end_pos": 110 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 538, "end_pos": 540 }, { "start_pos": 634, "end_pos": 636 }, { "start_pos": 665, "end_pos": 667 }, { "start_pos": 761, "end_pos": 763 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": 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"sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PFD5-1", "uniprot_ac": "A0A8M9PFD5", "uniprot_id": "A0A8M9PFD5_DANRE", "mass": { "chemical_mass": 31762.0, "monoisotopic_mass": 31762.0 }, "refseq": { "ac": "XP_021329892", "name": "olfactory receptor 1468", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329892" }, "gene_names": [ { "name": "or42a9", "type": "recommended", "evidence": [ { "id": "A0A8M9PFD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD5" } ] }, { "name": "or42a9", "type": "synonym", "evidence": [ { "id": "XP_021329892", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329892" } ] } ], "protein_names": [ { "name": "Olfactory receptor 1468", "type": "synonym", "evidence": [ { "id": "A0A8M9PFD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD5/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 1468", "type": "synonym", "evidence": [ { "id": "XP_021329892", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329892" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021329892.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329892" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "or42a9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PFD5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PFD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100148707", "url": "https://www.ncbi.nlm.nih.gov/gene/100148707", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052921", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052921", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100148707", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148707", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR26451", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26451", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR26451:SF966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR26451:SF966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13853", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13853", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021329892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329892", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070806-75", "url": "https://zfin.org/ZDB-GENE-070806-75", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MCVIYMSRRLHTAKYIAVFHLAFSDLCGSTAVIPKLIDMFLFGHQEISYEACLINMFFVFHLMNLQSMSLLVLAYDRLVAICFPLKYHAIITKKSVSLILGNMWLFSIFLFATLAGLVNRLSFCRSTVVSSHFCDHGPVISLSCNSNFINYLMAYISFGLLICMPMLLITISYCCIAAALFKIAHGADRIKAMKTCTSHLMLVAILYLPILSLNIKSIAISIDLNSRIINNSLTQILPPMLNPIIYTLKTEEVMQAIKEMYRRRRKVNTMMEQNVKQRK", "length": 279, "header": "tr|A0A8M9PFD5-1|A0A8M9PFD5_DANRE Isoform 1 of Olfactory receptor 1468 OS=Danio rerio OX=7955 GN=or42a9 PE=3 SV=3 CANONICAL=A0A8M9PFD5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PFD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD5/entry#A0A8M9PFD5-1", "sequence": { "sequence": "MCVIYMSRRLHTAKYIAVFHLAFSDLCGSTAVIPKLIDMFLFGHQEISYEACLINMFFVFHLMNLQSMSLLVLAYDRLVAICFPLKYHAIITKKSVSLILGNMWLFSIFLFATLAGLVNRLSFCRSTVVSSHFCDHGPVISLSCNSNFINYLMAYISFGLLICMPMLLITISYCCIAAALFKIAHGADRIKAMKTCTSHLMLVAILYLPILSLNIKSIAISIDLNSRIINNSLTQILPPMLNPIIYTLKTEEVMQAIKEMYRRRRKVNTMMEQNVKQRK", "length": 279, "header": "tr|A0A8M9PFD5-1|A0A8M9PFD5_DANRE Isoform 1 of Olfactory receptor 1468 OS=Danio rerio OX=7955 GN=or42a9 PE=3 SV=3 CANONICAL=A0A8M9PFD5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100148707", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148707", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096P6M5-1", "protein_name": "Olfactory receptor family 1 subfamily E member 35B", "gene_name": "Or1e35b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGNNQTMILEFLLLGLPIPTEYHLLFYALFLAMYLTTILGNLLIIVLVRLDSHLHMPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQVLSISYAGCLTQLYFFMVFADMESFLLVVMAYDHYVAICFPLHYTTIMSTKVCASLLILLWMLTTSHALLHTLLLARLSFCEKNVILHFFCDITALLKLSCSDTYVNEMMMYILGGLISVIPFLFIVMSYVRIFFSIFKFPSIQDIHKVFSTCGSHLSVVTLFHGTIFGLYLCPSGNNSTVKEIAMAMMYTVVTPMLNPFIYSLRNRDMKRALIRVICTKKISL", "length": 312 }, "evidence": [ { "id": "RGD:1333178", "url": "https://alliancegenome.org/gene/RGD:1333178#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0A0MY21-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e1e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGNNQTIISYFLLLGLPIPPKHHHLFYALFLAMYLTTILGNLIIIILIRLDNHLHTPMYFFLSNLSFNDLCFSSVTVPKLLLNMQSQVPSIPYAGCLAQMYFFLFFGDLESLLLVAMAYDRYVAICFPLHYTSIMSPKLCMSLLLLSCMLTALYAMLHTLLLTRLSFCENNMIPHFFCHLSALLKLACSDIHINELVILIIGGLVVILPFILITVSYACIVSSILKVPSTRGIHKIFTTCGSHLSVVSLFYGTIIGLYLCPSANNSTLKDTVMSMMYTVMTPMLNPFIYSLRNKDIKGALKRVLQKKILF", "length": 311 }, "evidence": [ { "id": "RGD:1333253", "url": "https://alliancegenome.org/gene/RGD:1333253#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0A0MY38-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e20b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVMNNQTVITQFLLLGLPIPPEHQQLFYALLLAMYLTTVLGNLIIIILIHLDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDTSITYVGCLTQMYFFLLFGSLEIFLLVVLAYDRYVAICLPLQYSSIMSPNLCVCLVVLSWVFTVLYSLLHTLLLTRLSFCEDNLIRHFFCDITALFKLACSDIYINELTVFILGGLVSVTSFLLIIVFYIQIVSSILRISSTRVIHKVFSTCGSHLSVVSLFYGTIIGLYFCPSSNISTVKETGMALMYTVVTPMLNPFIYTLRNRDMKDALIRVLFKKKISL", "length": 312 }, "evidence": [ { "id": "RGD:1332851", "url": "https://alliancegenome.org/gene/RGD:1332851#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K0L2-1", "protein_name": "Olfactory receptor family 12 subfamily J member 2B", "gene_name": "Or12j2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNGTLVTEFLILGFSEMPHLRVPLLSFLCLYMAAISGNLLIMVTVSASPALHTPMYFFLVNLAVVDILCTSTILPKLLDIMVGGRTISYGGCMAQLFFFTWSMGAELLLFSAMAYDRFVAICCPLHYSTWMGPRVCAFLAGLVWSISLTNTSVNTSLVLHLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEVMAFAADVFLAVGNFSVIILSYGFIVTSILKIRSTEGKQRAFSTCSAHLFVVTMYYSTIIYTYIRPASSYSLNKDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRKLLSSC", "length": 303 }, "evidence": [ { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K4J3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e26b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIRNNQTVISQFLLLGLPTSPEQQHLFYALFLAMYLTTIMGNFIIIIFILLDSHLHTPMYMFLGNLSFSDLCFSSVTIPMMLQNMKSQDTSISYPGCLTQMYFYMVFANLENFLLMVMAYDRYVAICFPLRYTSIMSPILCVSLVFMSWVICMLSSLLHTLLVVKLSFCEDNIIPHFFCDISALLMLACSDIHINELLIFYLGGTSIVIPFFLIVVSYTQIVWSILSVSSTRAIHKVFSTCGSHLSVVSLFYGTIIGLYLSPSANSSTVKKTAMTMMYTLVTSMLNPFIYSLRNRDMKEALIRILYKKKISL", "length": 312 }, "evidence": [ { "id": "RGD:1333088", "url": "https://alliancegenome.org/gene/RGD:1333088#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K8X6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRRNQTAISQFLLLGLPIPPEYQHLFYALFLAMYLTTVLGNLTIIILILLDSHLHTPMYLFLSNLSFADLCFSSVTMPKFLQNMQSQVPSIPYAGCLAQIYFFLYFGDLGNFLLVAMAYDRYVAICFPLHYMSIMSPKLCVSLVVLSWVLTTFHAMLHTLLMARLSFCAENVIPHFFCDISALLKLSCSDTHVNELVIFVMGGIILVIPFVLIIVSYVRIVSSILKVPSARGIRKAFSTCGSHLSVVSLFYGTVIGLYLCPSANNSTVKETVMSLMYTMVTPMLNPFIYSLRNKDIKDALEKIMCKKQIPSFL", "length": 314 }, "evidence": [ { "id": "RGD:1333590", "url": "https://alliancegenome.org/gene/RGD:1333590#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0U1RNJ4-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e31", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIMKNQTVITQFLLLGLPILPEHQHLFYALFLAMYLTTALGNLLIIVLVQLDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNIQSQDPSIPYAGCLAQTYFFMVFGDMESFLLVAMAYDRYVAICFPLHYTSIMSPKLCGCLMLLLWMLTTSHAMMHTLLAARLSFCENNVILNFFCDLFVLLKLACSDTYVNELMIFIMSSLLIVIPFFLIVMSYARIIASILKVPSIQGIYKVFSTCGSHLSVVTLFYGTIIGLYLCPSGNNSTVKGTVMAMMYTVVTPMLNPFIYSLRNRDMKRALIRVICSKKISL", "length": 312 }, "evidence": [ { "id": "RGD:1332757", "url": "https://alliancegenome.org/gene/RGD:1332757#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YEU6-1", "protein_name": "Olfactory receptor 1R1", "gene_name": "OR1R1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPTNLTSAPVFLLLGLVDGTDAHPLLFLLCLGIYLLNALSNLSMVALVRSDGALRSPMYYFLGHLSLVDVCFTTVTVPRLLAGLLHPGQAISFQACFAEMYFFVALGITESYLLAAMSYDRPTAACRPLRYGALVTPWRCASLVRASWAVTHLHSLLHTLLLSALSYPYPTPVRPFFCDMTVMLSLATSDTSAAETAIFSEGLAVVLAPLLLVFLFLRAHPGRGARLAGGRRRAFSTCGAHLVAVAVALFFGSVLSVYFPPSSAYSARYDRLASVVYAVITPTLNPFINSLRNKEVKGALKRGLRWRAAPQEA", "length": 314 }, "evidence": [ { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A2I3BQG5-1", "protein_name": "Olfactory receptor", "gene_name": "Or12d16-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAPTSVYQGSNSVLLNQTLVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILLIVISDPRLHSPMYFFLGNLACLDICFSTVTVPKILDNFFSTSKAISFLGCITQLYFFHLLGSTEALLLAVMAFDRFVAICRPLHYPSIMNGQVCIQVAISIWAIPFVHALVHSILTSQLNFCGSNQIHHFFCDVKPLLELACGNTELNRWLLNTFTGTFAIGLFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVMIFYAPVLFIYINPDSGSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKLRILL", "length": 322 }, "evidence": [ { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A2I3BRW3-1", "protein_name": "Olfactory receptor", "gene_name": "Or12d15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAPTSVSQGGYSDIQELNPILFVMVLAMYFINVFGNGAIMMIVILDSRLYSPMYFFLGNLACLDICFSTVTVPKMLENFFSTSKAISFLGCITQLHFFHFLGCTDALLLTVMAFDRFVAICRPLHYPSIMNRQVCIQVAATIWAIPFLHALVHSIMTSQLNFCGSNRIHHFFCDVKPLLELACGNTELNRWLLNTLAGTIGIGLFFLTFLSYFYIVTYLFLKTHSCSMLHKALSTCASHFMVVMIFYAPVLFIYINPDSGSSLEKDRIIAVMYTVVTPALNPLIYALRNKEVRCALNRKLRILI", "length": 305 }, "evidence": [ { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A2I3BRX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or12d14-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAPTSVSQEGNSVLLNHTLVTEFLLLGVTDIQELNPILFVTVLAMYFVNVAGNGAILMIVISDPRLHLPMYFFLGNLACLDICFSTVTVPKMLENFFSTSKAISFLGCITQLHFFHFLGSTEALLLTVMAFDRFVAICRPLHYPAIMNSQVCIQVAISIWAIPFLHALVHSILTSQLNFCGSNHIHHFFCDVKPLLELACGNTELNRWLLNTLTGTVAIGLFFLTFLSYFYIVTYLFLKTRSCSMLHKALSTCASHFMVVMIFYAPVLFIYINPDSGSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRILL", "length": 322 }, "evidence": [ { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I5ZSD3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVMDNQSVITQFLLLGLPIAPKHQHLFYALFLAMHLTTILGNLIIIILIILDSHLHTLMYMFLNNLSFSDLCFSSVTMPKLLQNMQSQDTSISYAGCLTQMYFFMVFADMENFLLVVMAYDRYVAICFPLHYMSIMSTKLCVYVVVLFWALTVFYSMLHTLLMARLSFCEDNVIAHFFCDISALLKLACSDIYINELLIFILGGFVVVIPFLLIVVSYVQILSSILKLSSTQGIRKVFSTCGSHLCVVSLFYGTIIGLYLCPSANNSTMKVASMSLMYTVVTPMLNPFIYSLRNRDIKDALIRVLCKKKITM", "length": 312 }, "evidence": [ { "id": "RGD:1333854", "url": "https://alliancegenome.org/gene/RGD:1333854#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZUJ8-1", "protein_name": "Olfactory receptor family 1 subfamily E member 35", "gene_name": "Or1e35", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGNNQTLILEFLLLGLPIPSEYHLLFYALFLAMYLTTILGNLLIIVLVRLDSHLHMPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQVPPISYAGCLTQMYFLMVFADMEIFLLVVMAYDHYVAICFPLHYTSIMSTKLCASLVLLLWMLTTSHALLHTLLMARLSFCEKNVILHFFCDISALLKLSCSDTYVDEMMIYILGGLISIIPFLLIVMSYIRIFFSIFKFPSIHDIHKVFSTCGSHLSVVTLFYGTIFGIYLCPSGNNSTVKEIAMAMMYTVVSPMLNPFIYSLRNRDVKRTLIRVICIKKISL", "length": 312 }, "evidence": [ { "id": "RGD:1592971", "url": "https://alliancegenome.org/gene/RGD:1592971#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5L7-1", "protein_name": "Olfactory receptor", "gene_name": "ENSRNOG00000066569", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRINRTTSVTEFLFSGLPEFEDGRFLFFIPLFFIYVFIVIGNLIVFFAVRMDTRLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISKRRTISLIGCLLQMYFFHSLGNSEGILLTTMAIDRYIAICNPLRYPTIMTPRLCAQLSAGSCIFGFLVLLPEIAWISTLPFCGPNQIHQIFCDFEPVLRLACTDTSMILVEDVVHAVAIIFSVLVIAFSYIRIITVILRIPSGEGRRKAFSTCAAHLGVFLMFYGSVSLMYLRFSATFPPVLDTAIALMFAVLAPFFNPIIYSLRNKDMKTAIKKLLSSPTMLPTSAS", "length": 315 }, "evidence": [ { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AI34-1", "protein_name": "Olfactory receptor", "gene_name": "Olr1471", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIMNNKTVISQFLLLGLPIPPEHQQLFYALFLSMYLTTVLGNLIIIILILLDSHLHTPMYFFLSNLSFSDLCFSSVTMPKLLQNMQSQDTSISYATCLSQMYFLLVFGDLESFLLLVMAYDRYVAICFPLHYTSIMSPKLCVCLVLMSWVFNVLYSLLHTLLLSRLSFCENNVIRHFFCDISALLKLACSDIRINELMILILGGLIMVIPFLLIVVSYVQIVFSILKISSTQVIQKIFSTCGSHLSVVSLFYGTIFGLYLYPSANNSTVKETVMAMMCTVVTPMLNPFIYSLRNRDMKEALIRVLCKKKISLS", "length": 313 }, "evidence": [ { "id": "RGD:1332981", "url": "https://alliancegenome.org/gene/RGD:1332981#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AP46-1", "protein_name": "Olfactory receptor", "gene_name": "Olr1585", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDHVNCTWNWIFILAGFNTSGTLQQLAVFGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTTVPTLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLGVMALDRYLAICRPLHYHSLMSRQVQRELVLITWVAGFSAALVPAGLTATLPYCLKEVAHYFCDLGPVMQLACVDTSWHARVYIAVIGMINTCNLVFILGLYGGIVKAVLRLPSAASRAKAFSTCSSHITVVTLFFGSAFIVYVGPPEIRAEGRGKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIKGVLG", "length": 312 }, "evidence": [ { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AVC0-1", "protein_name": "Olfactory receptor family 1 subfamily E member 1D", "gene_name": "Or1e1d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGNNQTIISEFFLLGLPIPPEHQHLFYALFLTMYLTTVLGNLVIIIVIRLDSHLHTPMYFFLSNLSFSDLCFSSVTVPKLLQNMKSQVSSIPYAACLAQTYFFLFFADLESFLLVAMAYDHYVAICFPLHYSSIMSPKLCVSLVVLSWVLTMSHAMLHTLLLTRLSFCENSVIPIFFCDLSALLKLACSDIHINELMILIIGGLVVILPFLLLIVSYTRIISSILKVPSTRGIHKVFSTCGSHLSVVSLFYGTIIGLYLCPSANDSTLKDTVMSIMYTVVTPMLNPFIYSLRNKDMKGALKQVLQMKAVF", "length": 311 }, "evidence": [ { "id": "RGD:1596210", "url": "https://alliancegenome.org/gene/RGD:1596210#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B0Y0-1", "protein_name": "Olfactory receptor family 12 subfamily J member 4", "gene_name": "Or12j4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPINQSVVTMFFLQNFVDDPWIQNVLFCFFFALFVAAIAGNGLIITVIHSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVAENAISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRPLHYGTLMSGRVCIALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSPTFINDIMTVIADMFLTGLNFLLTMTSYGFIIASILRIRSAEGKKRAFSTCSAHLVVVTLYYSTVLYTYVRPALGTSGLLDKVIAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPN", "length": 307 }, "evidence": [ { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GCX5-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIMNNQTLISQFLLLGLPIPPENQHLFYALFLAIYLTTILGNFIIITLICLDSHLHTPMYFFLSNLSLTDLCFSSVTMPKLLQNMQSQDTSISYAGCLAQMYFFMVFANMENVLLVVMAYDRYVAICFPLRYTSIMSSKLCVSLVVLSWVFTILYSMLHTLLLARLSFCEDNVIPHFFCDITALLKLACSDIYINELMIFILGGFDIVIPFLLIVVSYVQIVCSILKFSTTRGIHKVFSTCGSHLSVVSLFYGTIIGVYICPSANNSTVKETAMALMYTVVTPMLNPFIYSLRNRDMKGALIRVLCKKQISL", "length": 312 }, "evidence": [ { "id": "RGD:1333517", "url": "https://alliancegenome.org/gene/RGD:1333517#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1NL35-1", "protein_name": "Odorant receptor 109-7", "gene_name": "or42a7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSNSSANVAFVRPATFFLNGFSNFPHAKYYYLFLSLVYAVTVLENSFIMCIIYLSRRLHTAKYIAVFHLALCDLCGSSAVIPKVVDTFLFDHQDISYAACMANIFFVFHFMNVQSLTLLVMAYDRLVAICFPLRYHEIVTKTSMLLILGVIWTFSLIFFSVFVDSINRLSFCRTNVINNYFCDYCTVYRLACNDNSINILMGKLGNDLLIFTPLILVFISYFCISLALFKIAHAVDRTKAIKTCTTHLMLVAIFYIPILSNNIAALTTPFTSDIQIINNSLTQTIPPMLNPIIYTLKTDEVMQSVKELYKRSRMNTIRVSKTKC", "length": 325 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" }, { "id": "RGD:1592971", "url": "https://alliancegenome.org/gene/RGD:1592971#orthology", "database": "AGR" }, { "id": "RGD:1596210", "url": "https://alliancegenome.org/gene/RGD:1596210#orthology", "database": "AGR" }, { "id": "RGD:1333590", "url": "https://alliancegenome.org/gene/RGD:1333590#orthology", "database": "AGR" }, { "id": "RGD:1333854", "url": "https://alliancegenome.org/gene/RGD:1333854#orthology", "database": "AGR" }, { "id": "RGD:1332757", "url": "https://alliancegenome.org/gene/RGD:1332757#orthology", "database": "AGR" }, { "id": "RGD:1333952", "url": "https://alliancegenome.org/gene/RGD:1333952#orthology", "database": "AGR" }, { "id": "RGD:1359186", "url": "https://alliancegenome.org/gene/RGD:1359186#orthology", "database": "AGR" }, { "id": "RGD:1333253", "url": "https://alliancegenome.org/gene/RGD:1333253#orthology", "database": "AGR" }, { "id": "RGD:1333088", "url": "https://alliancegenome.org/gene/RGD:1333088#orthology", "database": "AGR" }, { "id": "RGD:1334190", "url": "https://alliancegenome.org/gene/RGD:1334190#orthology", "database": "AGR" }, { "id": "RGD:1333644", "url": "https://alliancegenome.org/gene/RGD:1333644#orthology", "database": "AGR" }, { "id": "RGD:1334228", "url": "https://alliancegenome.org/gene/RGD:1334228#orthology", "database": "AGR" }, { "id": "RGD:1334013", "url": "https://alliancegenome.org/gene/RGD:1334013#orthology", "database": "AGR" }, { "id": "RGD:1333178", "url": "https://alliancegenome.org/gene/RGD:1333178#orthology", "database": "AGR" }, { "id": "RGD:1332851", "url": "https://alliancegenome.org/gene/RGD:1332851#orthology", "database": "AGR" }, { "id": "RGD:1333517", "url": "https://alliancegenome.org/gene/RGD:1333517#orthology", "database": "AGR" }, { "id": "RGD:1333012", "url": "https://alliancegenome.org/gene/RGD:1333012#orthology", "database": "AGR" }, { "id": "RGD:1333989", "url": "https://alliancegenome.org/gene/RGD:1333989#orthology", "database": "AGR" }, { "id": "RGD:1334253", "url": "https://alliancegenome.org/gene/RGD:1334253#orthology", "database": "AGR" }, { "id": "RGD:1332981", "url": "https://alliancegenome.org/gene/RGD:1332981#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2B4K9-1", "protein_name": "Odorant receptor 111-2 isoform X1", "gene_name": "or42e3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQSYRKLARNNKSKSAMSSVNASFSQNISIVHPENFFIIGLTGIQHSGYYYIFLFFTYFISVIGNSVVLLIIALERNLHSAKYIGVFNLALADIGETSALIPNMMKNFLFDSQYISYNGCMANMFFVFLFSSMQSFTLVVMAYDRLIAICLPLRYHAIVNNTSMILMTLAIWAFNTFVVALMVSLINRLSFCESNMIQSYFCDHGPVFRLACNDNSMNKIMAYVISVLYILAPMVVIVFSYLAIFLALIKITTWEGRLKALKTCVSHLLLVGIFFLPVCCTYIAQVLLYLTPNARIISTSFSYAVPPVLNPIIYVLNTAEIKDIIKKMIKNKSAPIRENISK", "length": 342 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BH28-1", "protein_name": "Odorant receptor, family 42, subfamily A, member 4 isoform X1", "gene_name": "or42a4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSMQSNSSANVTFVRPATFFLSGLSNVPHAKYYYVFLSLVYVVTVLGNSFIMYIIYLARRLHTAKYIAVFHLAFSDLCGSSALIPKVIDTFLFDHQDISYEACMANMFFVLHFMNMQSLTLLALAYDRLIAICFPLRYHAIINKSAMFLIIGVMWIFSATFFSVVVGSVSRISFCISNVIDTYYCDFAPVFRLACNDNSLPILMGKLCFGILICMPPILIFVSYFCISLALLKIARGVDRNKAIKTCTSHLMLVAIFYLPILSNNIAYATTYINPNARLINNSLTQTIPPMLNPIIYTLKTDEVMQSIKELYKRSRVYATMERNRKCHGRK", "length": 332 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" }, { "id": "RGD:1592971", "url": "https://alliancegenome.org/gene/RGD:1592971#orthology", "database": "AGR" }, { "id": "RGD:1596210", "url": "https://alliancegenome.org/gene/RGD:1596210#orthology", "database": "AGR" }, { "id": "RGD:1333590", "url": "https://alliancegenome.org/gene/RGD:1333590#orthology", "database": "AGR" }, { "id": "RGD:1333854", "url": "https://alliancegenome.org/gene/RGD:1333854#orthology", "database": "AGR" }, { "id": "RGD:1332757", "url": "https://alliancegenome.org/gene/RGD:1332757#orthology", "database": "AGR" }, { "id": "RGD:1333952", "url": "https://alliancegenome.org/gene/RGD:1333952#orthology", "database": "AGR" }, { "id": "RGD:1359186", "url": "https://alliancegenome.org/gene/RGD:1359186#orthology", "database": "AGR" }, { "id": "RGD:1333253", "url": "https://alliancegenome.org/gene/RGD:1333253#orthology", "database": "AGR" }, { "id": "RGD:1333088", "url": "https://alliancegenome.org/gene/RGD:1333088#orthology", "database": "AGR" }, { "id": "RGD:1334190", "url": "https://alliancegenome.org/gene/RGD:1334190#orthology", "database": "AGR" }, { "id": "RGD:1333644", "url": "https://alliancegenome.org/gene/RGD:1333644#orthology", "database": "AGR" }, { "id": "RGD:1334228", "url": "https://alliancegenome.org/gene/RGD:1334228#orthology", "database": "AGR" }, { "id": "RGD:1334013", "url": "https://alliancegenome.org/gene/RGD:1334013#orthology", "database": "AGR" }, { "id": "RGD:1333178", "url": "https://alliancegenome.org/gene/RGD:1333178#orthology", "database": "AGR" }, { "id": "RGD:1332851", "url": "https://alliancegenome.org/gene/RGD:1332851#orthology", "database": "AGR" }, { "id": "RGD:1333517", "url": "https://alliancegenome.org/gene/RGD:1333517#orthology", "database": "AGR" }, { "id": "RGD:1333012", "url": "https://alliancegenome.org/gene/RGD:1333012#orthology", "database": "AGR" }, { "id": "RGD:1333989", "url": "https://alliancegenome.org/gene/RGD:1333989#orthology", "database": "AGR" }, { "id": "RGD:1334253", "url": "https://alliancegenome.org/gene/RGD:1334253#orthology", "database": "AGR" }, { "id": "RGD:1332981", "url": "https://alliancegenome.org/gene/RGD:1332981#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A8W9-1", "protein_name": "Odorant receptor 111-10", "gene_name": "or42c2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSLNASSYKNTSIVHPEYFFISGLSGIPYSSYYYVFLFITYFITIIGNSVVLLIIAFERSLHSPKYIVVFNLALADIGETNALIPNMMKTFLFDSQYISYNACLVNMFFVFLFSTMQSFTLVVLAYDRFVAICLPLRYHAIVNNSSITLILSAKWAFNSSMVALMVSLITRISFCDSNVIQSYFCDHGPVYRLACNDNSINRFMGSFITCLYLVVPLAIIILSYIGIFLALNKITTWESRLKALKTCVSHLLLVGIYFLPMSCTYIAAWLLALAPNARVITTSLAYTISPMLNPIIYVLNTAEIKDLLRKMFKNKSAPSKDNIAK", "length": 326 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0L448-1", "protein_name": "Olfactory receptor family 12 subfamily D member 2", "gene_name": "Or12d2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSNMEVMLNQTSVKEFVLLGVTDLQEPQPFLFAIFLIIYFVNITGNGAILMIVILDQKLHSPMYFFLGNLACLDICYSTVTVPKMLKNLLSTSKAISFLGCITQLHFFHFLGTTESLLLAVMAFDRFVAICKPLHYPIIMNWQICILMAVTIWTIAFLHALLHSVMTSRLSFCGPNHVHHFFCDVKPLLELACGNTELNLWLLNTVTGTVASVPFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVILFYAPVLFTYIRPASGNSLDQDRIIAIMYSVVTPALNPLIYTLRNKEVRNALNRKVMSNQTSVTEFLLLGVTDIQELNPILFVIFFTIYFVNITGNGAILMIVILDPRLHSPMYFFLGNLACLDICFSTVTVPKMLENLLSTSKAISFLGCITQLHFFHFLGSTEALLLPVMAFDRFVAICRPLHYSVIMNRQLCSHMTVTIWIMGFLHALLHSVMTSRLSFCGPNHVHHFFCDIKPLLDLACGNTELNLWLLNTVTGTIALTPFFLTFLSYFYIITYLFLKTHSCSMLHKALSTCASHFMVVILLYVPVLFNYIRPASSSALDQERIIAIMYSVVTPALNPLIYTLRNKEVRNALNKKVRRWL", "length": 619 }, "evidence": [ { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LA85-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "YNMIEENQTVISQFLLMGLPIPSEHQQLFYALFLSMYLTTVLGNLIIIILICLDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDTSILYAGCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFPLHYVSIMSPKLCVSLVVLSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTHVNELVIFVMGGIILVIPFVLIIVSYVRIVSSILKVPSARGIRKAFSTCGSHLSVVSLFYGTVIGLYLCPSANNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDMKGALNRVICKKKVFFCL", "length": 316 }, "evidence": [ { "id": "RGD:1333989", "url": "https://alliancegenome.org/gene/RGD:1333989#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LCC4-1", "protein_name": "Olfactory receptor", "gene_name": "Or4e5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKAVLINQTSVTSFRLTGLSANPKVQMFVFFIFLVFYVMTLVGNILIVITIIFDHRLHTPMYFFLSNLSFIDVCHSTVTVPKMLSDTLSDEKVISFDACVVQIFFLHLFACTEIFLLTVMAYDRYVAICKPLRYMTIMNWKVCTVLGVAMWTAGTVHSISFTSLTIKLPYCGPDEIDNFFCDVPQVIELACTDTRITEILVVSNSGMISMVCFVIIVVSYAVILVSLRQQISDGKRKALSTCAAHLTVVTLFLGHCIFIYSRPSISLPEDKIVSAFFTAVTPLLNPIIYTFRNEDMKSALKKLIRRKERKEK", "length": 313 }, "evidence": [ { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LFF4-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e23", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIMNNQTVISQFILLGLPIPPEHQHLFYALFLAMYLTTILGNFIIIILILLDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDTSISYDGCLTQMYFLLVFGDLESILLLVMAYDRYVAVCFPLHYMSIMSTKLCVCLMVLSWAFTLLYSMLHTILLAKLSFCEDNVIHHFFCDISALLKLACSDIHINELMIFIMGGLVSIIPFLLIVVSYVQIVFSILNVSSAHVLHKIFSTCGSHLSVVSLFYGTIFGLYLCPSTNSSIVKETAMAMMCTVVTPMLNPFIYSLRNRDVKDALITLLCRKKSSL", "length": 312 }, "evidence": [ { "id": "RGD:1333644", "url": "https://alliancegenome.org/gene/RGD:1333644#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LFJ8-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e1c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNQMQGTTERNQTAVSQFLLLGLPIPMEHHLLFYALFLAMYLTTVLGNLLIISIIHLDSHLHTPMYSFLSNLSFSDLCFSSVTMPKLLQSMQSQVPSIPYAGCLAQMYFFLFFADLESFLLVAMAYDRYVAICFPLHYMSIMSPKLCVSLVVLSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTHVNELVIFVMGGIILVIPFVLIIVSYVRIVSSILKVPSARGIRKAFSTCGSHLSVVSLFYGTVIGLYLCPSANNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDIKGALIRVLCKKKILFCL", "length": 320 }, "evidence": [ { "id": "RGD:1334228", "url": "https://alliancegenome.org/gene/RGD:1334228#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHQ4-1", "protein_name": "Olfactory receptor family 13 subfamily G member 1", "gene_name": "Or13g1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TMNFSIVNEFMILGLTQKSELQGILFIVFLCIYLVALLGNLLIVVAIIYNTTLHTPMYILLLALAVVDIICTTSIIPKMLGTMLTSENSISYGGCMSQLFFFTWSLGAEMVLFTTMAYDRYVAICFPLRYSTIMNHYTCVALLSIVMAIAVTNSWVHTGLILRLTFCGPNTVDHFFCEIPPLLALSCSPVRVNEVMVYVADITLAVGDFTLTCISYGFIIAAILRIRTTEGKKKAFSTCSSHLMVVSLYYSPVIYTYIRPASSYTFEKDKVVAALYTLVTPTLNPIVYSFRNKEMQSGIRKVFAFLKG", "length": 308 }, "evidence": [ { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LI97-1", "protein_name": "Olfactory receptor", "gene_name": "Or6k6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVIEFLFSVFPPLHEGGLLFFILLILVYAFIISGNLVIFVAVQLDLALHTPMYFFISVLSFLEIWYTTTTIPKMLSSLVSEKKTISLGGCLMQMYFFHSLGITEGCVLTAMSIDRYIAICYPLRYPTIMTSKLCIQLTAGSCFCGFLLVLPEIAWIATLPFCGSNKIHQIFCDFTPVLRLACTDTSLVVIVDAIHAVEILASFLVIALSYIRIIMVILGMPSAEGRHKAFSTCAAHLAVFLLFFGSVAVMYLRFSATYSVFWDTVIAVTFVILAPFLNPIIYSLRNKEMKDAIGRLFHRKRDARAQK", "length": 307 }, "evidence": [ { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LNM5-1", "protein_name": "Olfactory receptor family 12 subfamily J member 3", "gene_name": "Or12j3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPVNQSVVTMFILQNFVDDPWIQDVLFCLFFALFMMAIAGNGLIIMTIYSSANLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVAENAISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRPLHYGTLMNGRACVALATFVWFTGALNSLVLTCLVLPLSFCGPNLITHFFCEIPSVLMLSCSSTFINDIMTVITDMFLTGLNFLLTMTSYVFIIASILRIRSAEGKKRAFSTCSAHLVVVTLYYSTVLYTYVRPALGTAGLLDKAVAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLLFPH", "length": 307 }, "evidence": [ { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LWC7-1", "protein_name": "Olfactory receptor", "gene_name": "Olr1505", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGNNKTVISHFVLLGLPITPEHHHLFYSVFLAMYLTTILGNLIIIILICLDTNLHTPMYLFLGNLSFTDLCFSSVTMPKLLQNMKSQVPSIPYAGCLTQMYFFLFFGDLESFLLVAMAYDRYVAICFPLHYTSIMSPKLCVSLVLLSWVITTSHAMLHTLLLTRLSFCENNVIPHFFCDLSALLKLACSDIHINELVVLIIGGLVVILPFLLIIVSYTLIVSSILKVPSTRGIHKVFSTCGSHLSVVSLFYGTIIGLYLCPSANNSTLKDTVMSMMYTVVTPMLNPFIYSLRNRDMKAALKRVLQKKTVF", "length": 311 }, "evidence": [ { "id": "RGD:1334253", "url": "https://alliancegenome.org/gene/RGD:1334253#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58HBV7-1", "protein_name": "Odorant receptor 111-3 isoform X1", "gene_name": "or42d1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFLFFMLTFLKLAQNIKRKTAMSSVNASFSQNISIVRPEYFFISGLSGIPYSSYYYIFLFVVYFISVIGNSVVLLIIAVDRSLHSPKYIGVFNLALADIGETNALIPNMMKTFLFNSQYISYNGCMANMFFVFLFNSIQSFTLVALAYDRFIAICLPLRYHAIVNNTSMILIFLAIWAFNSSVVASMVSMITRLSICKSNVIPSYFCDHGPIFRLACNDIKINEFFAFFISILYLTMPMVIIALSYLNIFLALIKITTWEGRLKALKTCVSHLLLVGIFFLPLLCTYIAQVLLALTPNARVISTSLSYAIPPMLNPIIYVLNTAEIKYIIRKLFKRRLRSVSDNISK", "length": 347 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZIK6-1", "protein_name": "Olfactory receptor", "gene_name": "Or10aa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDHVNYTWTRTFILAGFTTSGTLQQLSVFGTLCIYLLTIAGNIFIIVLVQADSGLSTPMYFFISVLSFLEIWYVSTSVATLLHTLLHGHSPIPSAACFIQLYVFHSLGMTECYLLSVMALDRYLAICRPLHYHALMSRQVKIQLVLITWVAGFSVALVPAGLTASLPYCLKEVAHYLCDLEPVIRLACVDTSWHARVYITVIGIIITCNLVSILGLYGGIAKAVLRLPSAASRAKAFSTCSSHITVVTLFYGSAFIVYVGPPEIRAEGRDKLIALVYTLFTPFFNPIIYTLRNKEVKAAFKRVTQRIQGVLS", "length": 312 }, "evidence": [ { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A4S6-1", "protein_name": "Olfactory receptor family 1 subfamily R member 1", "gene_name": "Or1r1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVTNLTYRPQFQLLGLMDGADTHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLVTLLHPGQAMSFQDCFAQMYFFVALGITESYLLAAMSYDRVVAVCRPLHYGVVMTPWRCFVLVAASWTVAHLHSLLHTLLISALSYPRSAPVHHFFCDMTVMLSLATSDTSTAETAIFSEGLAVVLTPLILVSLSYARILVAVLGMQTTGGRHRVFSTCGAHLVVVSLFFGSVLSVYFRPSFGYSARYDRMASVVYAVVTPTLNPFIYSLRNKEVKGALKRGFRWRAAAQDE", "length": 314 }, "evidence": [ { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ACU7-1", "protein_name": "Olfactory receptor", "gene_name": "Or12d13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIPTSVFQTGNSVLLNPTLVTEFLLSGVTDIQELNSILFVTVLAMYFVNVFGNGAIMMIVSLDPRLHSPMYFFLGNLACLDICFSTVTVPKMLENFFSTSKAISFLGCITQLYFFHFLGSTEALLLTIMAFDRFVAICRPLHYPSIMNRQVCIQMAVFIWAIPFLHALVHSILTYQLNFCGSNHIHHFFCDVKPLLELACGNTELNRWLLNTFTGTFAIGLFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVIIFYAPVLFIYINPDSGSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRIQL", "length": 322 }, "evidence": [ { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADC0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4e2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGALNQTRVTEFVFLGLTDNWVLEILFFIPFTVTYVLTLLGNVLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLVRKTISFDNCIAQLFFLHLFACAEIFLLTIMAYDRYVAICIPLHYPNVMNMKVCVQLVFALWLGGTVHSLVQTFLTIRLPYCGPNTIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTSYTVILFSLRKQSAEGRRKALSTCSAHFMVVALFFGPCIFIYTWPDTSFSIDKVVSVFYTVVTPLLNPLIYTLRNEEVKTSMKHLRQRRICS", "length": 308 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AE91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKAVLINHTSVTSFRLTGLSANPKVQMAVFFIFLIFYVLTLVGNILIVITIIFDHRLHTPMYFFLSNLSFIDVCHSTVTVPKMLSDTLSEDKLISFDACVVQMFFLHLFACTEIFLLTVMAYDRYVAICKPLQYMTIMNWKVCMLLATALWTGGTIHSISLTSLTIKLPYCGPDEIDNFFCDVPQVIKLACTDTHIIEILIVSNSGLISVVCFVVLVVSYAVILVSLRQKISEGKRKALSTCAAHLTVVTLFLGHCIFIYSRPSTSLPEDKVVSVFFTAVTPLLNPIIYTLRNEDMKSALNKLIRRREK", "length": 310 }, "evidence": [ { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q0M4-1", "protein_name": "Olfactory receptor", "gene_name": "Or6k6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVIEFLFSVFPPLYEGGLLFFILLILVYAFIISGNLVIFVAVQLDMALHTPMYFFISVLSFLEIWYTTTTIPKMLSSLVSEKKTISLGGCLMQMYFFHSLGITEGCVLTAMSIDRYIAICYPLRYPTIMTSKLCIQLTAGSCFCGFLLVLPEIAWIATLPFCGSNKIHQIFCDFTPVLSLACTDTSLVVIVDAIHAVEILASFLVIALSYIRIIMVILGMPSAEGRHKAFSTCAAHLAVFLLFFGSVAVMYLRFSATYSVFWDTVIAVTFVILAPFLNPIIYSLRNKEMKDAIGRLFHQKRDVRAQK", "length": 307 }, "evidence": [ { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0Q2-1", "protein_name": "Olfactory receptor", "gene_name": "Or6k4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRINRTTSVTEFLFSGFPQFEDGSFLFFIPLFFIYIFIVIGNLIVFFAVRMDTRLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISKQRTISLIGCLLQMYFFHSLGNSEGILLTTMAIDRYVAICNPLRYPTIMTPRLCAHLSAGSCIFGFLVLLPEIAWISTLPFCGPNQIHQIFCDFEPVLRLACTDTSMILVEDVVHAVAIIFSVLVIAISYMRIITVILRIPSGEGRRKAFSTCAAHLGVFLMFYGSVSLMYLRFSATFPPILDTAIALMFAVLAPFFNPIIYSLRNKDMKIAIKKLLCSQKMLPTSAS", "length": 315 }, "evidence": [ { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8M2-1", "protein_name": "Olfactory receptor", "gene_name": "Or10aa3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDHVNYTWTRTFILAGFTTSGTLQHLAVFGTLCIYLLTLAGNLFIIVLIQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGPSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRPLHYHALMSRQVQKQLVGVTWLAGFSAALVPAGLTASLPYCLKEVAHYFCDLAPVMQLACVDTSWHARLYIAVIGMINTCNLTFILGLYGGIVRAVLKLPSAASRAKAFSTCSSHITVVTLFFGSAFIVYVGPPEIRAEGRDKLIALVYTLLTPFFNPIIYTLRNKEVKEAFKRVTQRINAVLK", "length": 312 }, "evidence": [ { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LV77-1", "protein_name": "Olfactory receptor", "gene_name": "Or12d14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LLNQTLVTEFLLMGVTDIQELNPILFLTFLVMYFVNVFGNGSILMIVILDPRLHSPMYFFLGNLACVDICFSTVTVPKMLENFFSTSKAISFLGCITQLYLFHFLGSTEALLLTVMAFDRFVAICRPLHYPSIMNSHVCIQLTVVIWAIPFIPALLHSILTSQLSFCGSNHVHHFFCDVKPLLELACGNTELNRWLLNTFTGTVAIALFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHVMVVIIFYAPVLFIYINPDSRSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRIQL", "length": 308 }, "evidence": [ { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LVN2-1", "protein_name": "Olfactory receptor", "gene_name": "Olr1481", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTERNQTVISQFLLLGLPMPPEHQHVFYALFLAMYLTTILGNLIIIILILLDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQVPSIPYSGCLAQIYFFLFFGDLGNFLLVAMAYDRYVAICFPLHYMSIMSPKLCVSLVVLSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLACSDTRVNEVVIFIVVILFLVLPFALIIMSYVRIVSSILKVPSSQGIYKAFSTCGSHLSVVSLFYGTVIGLYLCPSSNNSTVKETVMSLMYTVVTPMLNPFIYSLRNRDIKGAMERIFCKRKIQLNL", "length": 314 }, "evidence": [ { "id": "RGD:1333952", "url": "https://alliancegenome.org/gene/RGD:1333952#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F6PUI1-1", "protein_name": "Olfactory receptor", "gene_name": "Or12d2c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAPTSVSQGGKSVLLNQTLFTEFLLLGVTDIQELNPILFVTVLAMYFVNVFGNGAIMMIVILDPRLHSPMYFFLGNLACLDICFSTVTVPKMLENFFSTSKAISFLGCITQLHFFHFLGSTEALLLTVMAFDRFVAICRPLHYPSIMNRQVCIQVAVSIWAIPFLHALVHSILTSRLNFCGSNHIHHFFCDVKPLLELACGNTELNRWLLNTLTGTVAIGLFFLTFLSYFYIISYLFLKTHSCSMLHKALSTCASHFMVVIIFYAPVLFIYINPDSGSSLEKDRIIAVMYTVVTPALNPLIYTLRNKEVRGALNRKIRIQL", "length": 322 }, "evidence": [ { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O42169-1", "protein_name": "Odorant receptor 111-6", "gene_name": "or42c3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNFLNESFYQNISFVHPQYFYIIGLSGTPYSSYFYVFLFITYFITLFGNSVVLLIIALDRSLHSPKYIGVFNLALADIGETNALIPNMVKTFLFDSQYISYNACLANMFFVFLFSSIQSFALLVLAFDRFVAICLPLRYHALVNNTTMLLAFAAVWAFNSFVVALMVSLITRLSFCQSNMIQSYFCDHGPVYRIACNDFSINKFMAFLITGLYLVIPLFLIVLSYLGIFLALTKITTFEGRIKALKTCVSHLLLVGTLFLPLFCTYFAQLLLSLSPNARVICTSLAYTIPPMLNPIIYVLNTAEIKDIIWKVFKNKSVAVESISK", "length": 325 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P0C645-1", "protein_name": "Olfactory receptor 4E1", "gene_name": "OR4E1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEAILLNQTSLVTYFRLRGLSVNHKARIAMFSMFLIFYVLTLIGNVLIVITIIYDHRLHTPMYFFLSNLSFIDVCHSTVTVPKMLRDVWSEEKLISFDACVTQMFFLHLFACTEIFLLTVMAYDRYVAICKPLQYMIVMNWKVCVLLAVALWTGGTIHSIALTSLTIKLPYCGPDEIDNFFCDVPQVIKLACIDTHVIEILIVSNSGLISVVCFVVLVVSYAVILVSLRQQISKGKRKALSTCAAHLTVVTLFLGHCIFIYSRPSTSLPEDKVVSVFFTAVTPLLNPIIYTLRNEEMKSALNKLVGRKERKEEK", "length": 315 }, "evidence": [ { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DN82-1", "protein_name": "Olfactory receptor 12D1", "gene_name": "OR12D1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLNTTSVTEFLLLGVTDIQELQPFLFVVFLTIYFISVAGNGAILMIVISDPRLHSPMYFFLGNLSCLDICYSSVTLPKMLQNFLSAHKAISFLGCISQLHFFHFLGSTEAMLLAVMAFDRFVAICKPLRYTVIMNPQLCTQMAITIWMIGFFHALLHSLMTSRLNFCGSNRIYHFFCDVKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITHLFFKTHSFSMLRKALSTCASHFMVVILLYAPVLFTYIHHASGTSMDQDRITAIMYTVVTPVLNPLIYTLRNKEVKGAFNRAMKRWLWPKEILKNSSEA", "length": 320 }, "evidence": [ { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P23269-1", "protein_name": "Olfactory receptor 1496", "gene_name": "Olr1496", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNQTFITQFLLLGLPIPEEHQHLFYALFLVMYLTTILGNLLIIVLVQLDSQLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMRSQDTSIPYGGCLAQTYFFMVFGDMESFLLVAMAYDRYVAICFPLHYTSIMSPKLCTCLVLLLWMLTTSHAMMHTLLAARLSFCENNVVLNFFCDLFVLLKLACSDTYINELMIFIMSTLLIIIPFFLIVMSYARIISSILKVPSTQGICKVFSTCGSHLSVVSLFYGTIIGLYLCPAGNNSTVKEMVMAMMYTVVTPMLNPFIYSLRNRDMKRALIRVICSMKITL", "length": 310 }, "evidence": [ { "id": "RGD:1332757", "url": "https://alliancegenome.org/gene/RGD:1332757#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23273-1", "protein_name": "Olfactory receptor 1500", "gene_name": "Olr1500", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTGNNQTLILEFLLLGLPIPSEYHLLFYALFLAMYLTIILGNLLIIVLVRLDSHLHMPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQVPSISYTGCLTQLYFFMVFGDMESFLLVVMAYDRYVAICFPLRYTTIMSTKFCASLVLLLWMLTMTHALLHTLLIARLSFCEKNVILHFFCDISALLKLSCSDIYVNELMIYILGGLIIIIPFLLIVMSYVRIFFSILKFPSIQDIYKVFSTCGSHLSVVTLFYGTIFGIYLCPSGNNSTVKEIAMAMMYTVVTPMLNPFIYSLRNRDMKRALIRVICTKKISL", "length": 312 }, "evidence": [ { "id": "RGD:1334013", "url": "https://alliancegenome.org/gene/RGD:1334013#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23274-1", "protein_name": "Olfactory receptor 1468", "gene_name": "Olr1468", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEENQTVISQFLLLGLPIPSEHQHVFYALFLSMYLTTVLGNLIIIILIHLDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQVPSIPFAGCLTQLYFYLYFADLESFLLVAMAYDRYVAICFPLHYMSIMSPKLCVSLVVLSWVLTTFHAMLHTLLMARLSFCADNMIPHFFCDISPLLKLSCSDTHVNELVIFVMGGLVIVIPFVLIIVSYARVVASILKVPSVRGIHKIFSTCGSHLSVVSLFYGTIIGLYLCPSANNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDMKEALIRVLCKKKITFCL", "length": 314 }, "evidence": [ { "id": "RGD:1334190", "url": "https://alliancegenome.org/gene/RGD:1334190#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P30953-1", "protein_name": "Olfactory receptor 1E1", "gene_name": "OR1E1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMGQNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPMYLFLSNLSFSDLCFSSVTIPKLLQNMQNQDPSIPYADCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFPLHYTAIMSPMLCLALVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLAFSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSILKVPSSKGICKAFSTCGSHLSVVSLFYGTVIGLYLCSSANSSTLKDTVMAMMYTVVTPMLNPFIYSLRNRDMKGALSRVIHQKKTFFSL", "length": 314 }, "evidence": [ { "id": "RGD:1592971", "url": "https://alliancegenome.org/gene/RGD:1592971#orthology", "database": "AGR" }, { "id": "RGD:1596210", "url": "https://alliancegenome.org/gene/RGD:1596210#orthology", "database": "AGR" }, { "id": "RGD:1333590", "url": "https://alliancegenome.org/gene/RGD:1333590#orthology", "database": "AGR" }, { "id": "RGD:1333854", "url": "https://alliancegenome.org/gene/RGD:1333854#orthology", "database": "AGR" }, { "id": "RGD:1332757", "url": "https://alliancegenome.org/gene/RGD:1332757#orthology", "database": "AGR" }, { "id": "RGD:1333952", "url": "https://alliancegenome.org/gene/RGD:1333952#orthology", "database": "AGR" }, { "id": "RGD:1359186", "url": "https://alliancegenome.org/gene/RGD:1359186#orthology", "database": "AGR" }, { "id": "RGD:1333088", "url": "https://alliancegenome.org/gene/RGD:1333088#orthology", "database": "AGR" }, { "id": "RGD:1334190", "url": "https://alliancegenome.org/gene/RGD:1334190#orthology", "database": "AGR" }, { "id": "RGD:1333644", "url": "https://alliancegenome.org/gene/RGD:1333644#orthology", "database": "AGR" }, { "id": "RGD:1334228", "url": "https://alliancegenome.org/gene/RGD:1334228#orthology", "database": "AGR" }, { "id": "RGD:1334013", "url": "https://alliancegenome.org/gene/RGD:1334013#orthology", "database": "AGR" }, { "id": "RGD:1332851", "url": "https://alliancegenome.org/gene/RGD:1332851#orthology", "database": "AGR" }, { "id": "RGD:1333517", "url": "https://alliancegenome.org/gene/RGD:1333517#orthology", "database": "AGR" }, { "id": "RGD:1333012", "url": "https://alliancegenome.org/gene/RGD:1333012#orthology", "database": "AGR" }, { "id": "RGD:1333989", "url": "https://alliancegenome.org/gene/RGD:1333989#orthology", "database": "AGR" }, { "id": "RGD:1334253", "url": "https://alliancegenome.org/gene/RGD:1334253#orthology", "database": "AGR" }, { "id": "RGD:1332981", "url": "https://alliancegenome.org/gene/RGD:1332981#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47887-1", "protein_name": "Olfactory receptor 1E2", "gene_name": "OR1E2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMGQNQTSISDFLLLGLPIQPEQQNLCYALFLAMYLTTLLGNLLIIVLIRLDSHLHTPVYLFLSNLSFSDLCFSSVTMPKLLQNMQNQDPSIPYADCLTQMYFFLYFSDLESFLLVAMAYDRYVAICFPMHYTAICFLLHYTAIMSPMLCLSVVALSWVLTTFHAMLHTLLMARLCFCADNVIPHFFCDMSALLKLACSDTRVNEWVIFIMGGLILVIPFLLILGSYARIVSSILKVPSSKGICKAFSTCGSHLSVVSLFYGTVIGLYLCPSANSSTLKDTVMAMMYTVVTPMLTPFIYSLRNRDMKGALERVICKRKNPFLL", "length": 323 }, "evidence": [ { "id": "RGD:1592971", "url": "https://alliancegenome.org/gene/RGD:1592971#orthology", "database": "AGR" }, { "id": "RGD:1596210", "url": "https://alliancegenome.org/gene/RGD:1596210#orthology", "database": "AGR" }, { "id": "RGD:1333590", "url": "https://alliancegenome.org/gene/RGD:1333590#orthology", "database": "AGR" }, { "id": "RGD:1333854", "url": "https://alliancegenome.org/gene/RGD:1333854#orthology", "database": "AGR" }, { "id": "RGD:1332757", "url": "https://alliancegenome.org/gene/RGD:1332757#orthology", "database": "AGR" }, { "id": "RGD:1333952", "url": "https://alliancegenome.org/gene/RGD:1333952#orthology", "database": "AGR" }, { "id": "RGD:1359186", "url": "https://alliancegenome.org/gene/RGD:1359186#orthology", "database": "AGR" }, { "id": "RGD:1333253", "url": "https://alliancegenome.org/gene/RGD:1333253#orthology", "database": "AGR" }, { "id": "RGD:1333088", "url": "https://alliancegenome.org/gene/RGD:1333088#orthology", "database": "AGR" }, { "id": "RGD:1334190", "url": "https://alliancegenome.org/gene/RGD:1334190#orthology", "database": "AGR" }, { "id": "RGD:1333644", "url": "https://alliancegenome.org/gene/RGD:1333644#orthology", "database": "AGR" }, { "id": "RGD:1334228", "url": "https://alliancegenome.org/gene/RGD:1334228#orthology", "database": "AGR" }, { "id": "RGD:1334013", "url": "https://alliancegenome.org/gene/RGD:1334013#orthology", "database": "AGR" }, { "id": "RGD:1332851", "url": "https://alliancegenome.org/gene/RGD:1332851#orthology", "database": "AGR" }, { "id": "RGD:1333517", "url": "https://alliancegenome.org/gene/RGD:1333517#orthology", "database": "AGR" }, { "id": "RGD:1333012", "url": "https://alliancegenome.org/gene/RGD:1333012#orthology", "database": "AGR" }, { "id": "RGD:1333989", "url": "https://alliancegenome.org/gene/RGD:1333989#orthology", "database": "AGR" }, { "id": "RGD:1334253", "url": "https://alliancegenome.org/gene/RGD:1334253#orthology", "database": "AGR" }, { "id": "RGD:1332981", "url": "https://alliancegenome.org/gene/RGD:1332981#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P58182-1", "protein_name": "Olfactory receptor 12D2", "gene_name": "OR12D2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLNTTSVTEFLLLGVTDIQELQPFLFVVFLTIYFISVTGNGAVLMIVISDPRLHSLMYFFLGNLSYLDICYSTVTLPKMLQNFLSTHKAISFLGCISQLHFFHSLGSTESMLFAVMAFDLSVAICKPLRYTVIMNPQLCTQMAITIWVIGFFHALLHSVMTSRLNFCGSNRIHHFLCDIKPLLKLACGNTELNQWLLSTVTGTIAMGPFFLTLLSYFYIITYLFFKTRSCSMLCKALSTCASHFMVVILFYAPVLFTYIHPALESFMDQDRIVAIMYTVVTPVLNPLIYTLRNKEVKGALGRVIRRL", "length": 307 }, "evidence": [ { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P70526-1", "protein_name": "Olfactory receptor 1", "gene_name": "Olfr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTERNQTVISQFLLLGLPIPPEHQHVFYALFLSMYLTTVLGNLIIIILILLDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQVPSIPYAGCLSQIYFFLFFGDLGNFLLVAMAYDRYVAICFPLHYMSIMSPKLCVSLVVLSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLACSDTRVNEVVIFIVVSLFLVLPFALIIMSYVRIVSSILKVPSSQGIYKAFSTCGSHLSVVSLFYGTVIGLYLCPSSNNSTVKETVMSLMYTVVTPMLNPFIYSLRNRDIKGAMERIFCKRKIQLNL", "length": 314 }, "evidence": [ { "id": "RGD:1359186", "url": "https://alliancegenome.org/gene/RGD:1359186#orthology", "database": "AGR" }, { "id": "RGD:1333012", "url": "https://alliancegenome.org/gene/RGD:1333012#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2PRE1-1", "protein_name": "Odorant receptor 116-2", "gene_name": "or71aq2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENLSIIVSFELTLDPFSIPPGAKYPIFIFGIFIYMFGAFCNLTLLLLIFLTESLHKPMYFILFSLPLNDFVGITSMLPKVLSDILTETNKTYYPLCVLQGFLLHMYGGGVLFVLAAMAFDRYIAICMPLRYNALMTPRAVMGIVALVWGLDLFFIILLFALQSKYSRCRSDILNVFCDNPSLLKLTCSNTIVSNIIGLFNTAMIQIISVSIQAFSYVKILITCLATSKSDAKNKAINTCVSQLVIFIMFEIVATFTILSHRFTSVNADLQKIMGMLIFLVPPLLNPIVYGLNSHELRNNLLKVIHRKIAHM", "length": 312 }, "evidence": [ { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRJ4-1", "protein_name": "Odorant receptor 109-6", "gene_name": "or109-6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSIQTNPSANLTFVRPAKFFLSGLSNVPHAKYYYVFLSLAYVVTVLGNSFLMCIMYLSRRLHTAKYIAVFHLALSDLCGSSTVIPKVIDTLLFDHQDVSYEACLTHMFFIYHFMNLQSLTLLVMAYDRLVAICFPLRYLAIVTKPSMFLIVGVMWIFSVIYFSVLVGLVNRISFCGSRVIDSYFCDQGIIYKLACNDNSINLMMGKISFGLLMCTPFMLIVISYFFIALALLKISHGVDRIKAMKTCTSHLMLVAIGYLPLISNQIAALTTSIDPNTRIFNNSLRQVIPSMLNPIIYTLKTEEVMESIKDLYKRRKINTAIKRI", "length": 325 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" }, { "id": "RGD:1592971", "url": "https://alliancegenome.org/gene/RGD:1592971#orthology", "database": "AGR" }, { "id": "RGD:1596210", "url": "https://alliancegenome.org/gene/RGD:1596210#orthology", "database": "AGR" }, { "id": "RGD:1333590", "url": "https://alliancegenome.org/gene/RGD:1333590#orthology", "database": "AGR" }, { "id": "RGD:1333854", "url": "https://alliancegenome.org/gene/RGD:1333854#orthology", "database": "AGR" }, { "id": "RGD:1332757", "url": "https://alliancegenome.org/gene/RGD:1332757#orthology", "database": "AGR" }, { "id": "RGD:1333952", "url": "https://alliancegenome.org/gene/RGD:1333952#orthology", "database": "AGR" }, { "id": "RGD:1359186", "url": "https://alliancegenome.org/gene/RGD:1359186#orthology", "database": "AGR" }, { "id": "RGD:1333253", "url": "https://alliancegenome.org/gene/RGD:1333253#orthology", "database": "AGR" }, { "id": "RGD:1333088", "url": "https://alliancegenome.org/gene/RGD:1333088#orthology", "database": "AGR" }, { "id": "RGD:1334190", "url": "https://alliancegenome.org/gene/RGD:1334190#orthology", "database": "AGR" }, { "id": "RGD:1333644", "url": "https://alliancegenome.org/gene/RGD:1333644#orthology", "database": "AGR" }, { "id": "RGD:1334228", "url": "https://alliancegenome.org/gene/RGD:1334228#orthology", "database": "AGR" }, { "id": "RGD:1334013", "url": "https://alliancegenome.org/gene/RGD:1334013#orthology", "database": "AGR" }, { "id": "RGD:1333178", "url": "https://alliancegenome.org/gene/RGD:1333178#orthology", "database": "AGR" }, { "id": "RGD:1332851", "url": "https://alliancegenome.org/gene/RGD:1332851#orthology", "database": "AGR" }, { "id": "RGD:1333517", "url": "https://alliancegenome.org/gene/RGD:1333517#orthology", "database": "AGR" }, { "id": "RGD:1333012", "url": "https://alliancegenome.org/gene/RGD:1333012#orthology", "database": "AGR" }, { "id": "RGD:1333989", "url": "https://alliancegenome.org/gene/RGD:1333989#orthology", "database": "AGR" }, { "id": "RGD:1334253", "url": "https://alliancegenome.org/gene/RGD:1334253#orthology", "database": "AGR" }, { "id": "RGD:1332981", "url": "https://alliancegenome.org/gene/RGD:1332981#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRJ9-1", "protein_name": "Odorant receptor 109-5", "gene_name": "or42a2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQSNSSANTTFVRPATFFLNGLSNVPHVKYYYMFLSLVHVATVLGNSFLMSTIYLARRLHTAKYIVVFHLAFSDLCGSSTVVPKIIDTFLFEHQDILYEACLANMFFVYFFMSMQSLTLLILAYDRLVAICFPLRYHAIVTKPSMFLIIGAMWIFSLTYFSVLVGLVNRISFCGSNVIDSYFCDHGLIYKLACNDISINLLMGKMTFGLLMCTPLILIFLSYFFIALALLKIAHGGARIKAMKTCTSHLMLVAIGYFPLISNQIAALTTSIDPNTRIFNNSLRQVIPSMLNPIIYTLKTEEVMESMKDLYKRRKINTAIERKMKCERGN", "length": 329 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" }, { "id": "RGD:1592971", "url": "https://alliancegenome.org/gene/RGD:1592971#orthology", "database": "AGR" }, { "id": "RGD:1596210", "url": "https://alliancegenome.org/gene/RGD:1596210#orthology", "database": "AGR" }, { "id": "RGD:1333590", "url": "https://alliancegenome.org/gene/RGD:1333590#orthology", "database": "AGR" }, { "id": "RGD:1333854", "url": "https://alliancegenome.org/gene/RGD:1333854#orthology", "database": "AGR" }, { "id": "RGD:1332757", "url": "https://alliancegenome.org/gene/RGD:1332757#orthology", "database": "AGR" }, { "id": "RGD:1333952", "url": "https://alliancegenome.org/gene/RGD:1333952#orthology", "database": "AGR" }, { "id": "RGD:1359186", "url": "https://alliancegenome.org/gene/RGD:1359186#orthology", "database": "AGR" }, { "id": "RGD:1333253", "url": "https://alliancegenome.org/gene/RGD:1333253#orthology", "database": "AGR" }, { "id": "RGD:1333088", "url": "https://alliancegenome.org/gene/RGD:1333088#orthology", "database": "AGR" }, { "id": "RGD:1334190", "url": "https://alliancegenome.org/gene/RGD:1334190#orthology", "database": "AGR" }, { "id": "RGD:1333644", "url": "https://alliancegenome.org/gene/RGD:1333644#orthology", "database": "AGR" }, { "id": "RGD:1334228", "url": "https://alliancegenome.org/gene/RGD:1334228#orthology", "database": "AGR" }, { "id": "RGD:1334013", "url": "https://alliancegenome.org/gene/RGD:1334013#orthology", "database": "AGR" }, { "id": "RGD:1333178", "url": "https://alliancegenome.org/gene/RGD:1333178#orthology", "database": "AGR" }, { "id": "RGD:1332851", "url": "https://alliancegenome.org/gene/RGD:1332851#orthology", "database": "AGR" }, { "id": "RGD:1333517", "url": "https://alliancegenome.org/gene/RGD:1333517#orthology", "database": "AGR" }, { "id": "RGD:1333012", "url": "https://alliancegenome.org/gene/RGD:1333012#orthology", "database": "AGR" }, { "id": "RGD:1333989", "url": "https://alliancegenome.org/gene/RGD:1333989#orthology", "database": "AGR" }, { "id": "RGD:1334253", "url": "https://alliancegenome.org/gene/RGD:1334253#orthology", "database": "AGR" }, { "id": "RGD:1332981", "url": "https://alliancegenome.org/gene/RGD:1332981#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRK0-1", "protein_name": "Odorant receptor 109-4", "gene_name": "or42a6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSFIQSNSSANETFVRPATFFLSGLSNVPHAKYYYVFLSLVYVATVLGNSFIMCVIYMSRRLHTAKYIVVFHLAFSDLCGSSTVIPNVIDTFLFDHQEISYEACLANTFFTYHFMNLQSLTLLVMAYDRLVAICFPLQYHAIVTNAAMFSILGGMWIFSVTHFSVFVGLLNRLSFCKSNVIDSYFCDYSLINRLACNDNSVNIMMVKINFGLLICTPLILIFISYFCISLALFKIAHGVDRAKAIKTCTSHLMLVAIFFIPFLSNQIAILTTSVHLNTRLINSSLTQAIPPMLNPIIYTLKTDEVMQSVKELYKRKVNTTTERRMKWNSRNSKQKIQV", "length": 338 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" }, { "id": "RGD:1592971", "url": "https://alliancegenome.org/gene/RGD:1592971#orthology", "database": "AGR" }, { "id": "RGD:1596210", "url": "https://alliancegenome.org/gene/RGD:1596210#orthology", "database": "AGR" }, { "id": "RGD:1333590", "url": "https://alliancegenome.org/gene/RGD:1333590#orthology", "database": "AGR" }, { "id": "RGD:1333854", "url": "https://alliancegenome.org/gene/RGD:1333854#orthology", "database": "AGR" }, { "id": "RGD:1332757", "url": "https://alliancegenome.org/gene/RGD:1332757#orthology", "database": "AGR" }, { "id": "RGD:1333952", "url": 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"https://alliancegenome.org/gene/RGD:1333952#orthology", "database": "AGR" }, { "id": "RGD:1359186", "url": "https://alliancegenome.org/gene/RGD:1359186#orthology", "database": "AGR" }, { "id": "RGD:1333253", "url": "https://alliancegenome.org/gene/RGD:1333253#orthology", "database": "AGR" }, { "id": "RGD:1333088", "url": "https://alliancegenome.org/gene/RGD:1333088#orthology", "database": "AGR" }, { "id": "RGD:1334190", "url": "https://alliancegenome.org/gene/RGD:1334190#orthology", "database": "AGR" }, { "id": "RGD:1333644", "url": "https://alliancegenome.org/gene/RGD:1333644#orthology", "database": "AGR" }, { "id": "RGD:1334228", "url": "https://alliancegenome.org/gene/RGD:1334228#orthology", "database": "AGR" }, { "id": "RGD:1334013", "url": "https://alliancegenome.org/gene/RGD:1334013#orthology", "database": "AGR" }, { "id": "RGD:1333178", "url": "https://alliancegenome.org/gene/RGD:1333178#orthology", "database": "AGR" }, { "id": "RGD:1332851", "url": "https://alliancegenome.org/gene/RGD:1332851#orthology", "database": "AGR" }, { "id": "RGD:1333517", "url": "https://alliancegenome.org/gene/RGD:1333517#orthology", "database": "AGR" }, { "id": "RGD:1333012", "url": "https://alliancegenome.org/gene/RGD:1333012#orthology", "database": "AGR" }, { "id": "RGD:1333989", "url": "https://alliancegenome.org/gene/RGD:1333989#orthology", "database": "AGR" }, { "id": "RGD:1334253", "url": "https://alliancegenome.org/gene/RGD:1334253#orthology", "database": "AGR" }, { "id": "RGD:1332981", "url": "https://alliancegenome.org/gene/RGD:1332981#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRK4-1", "protein_name": "Odorant receptor 110-2", "gene_name": "or42b1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDFAENRNISIPSYFYISGFSGIPHMRYYYIFLSFVYIISFLGNSCLMFVIIIDRNLHTAKYIAVFNLSLSDICESTAVIPQLLDTFLFRNQLIPYRLCLYNMFSVFVSISTQSLTLAVLSFDRLVAICLPLRYHMIVTFRSMLVIIGLTWALTLLMVMTATIFISRLSFCKVIVTVNSFYCDHGPIYRSACSNNFPSSVIGSLYPIVILGLPVFFIIFSYTCIAVTLFRVTTPQDRQRATKTCTAHLILVAVFYLPITITYSLASIINTNTRIINLSLTSALPPMLNPIIYTFKTEEFMVSVKKLLKRKIIFPYLK", "length": 318 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRK5-1", "protein_name": "Odorant receptor 110-1", "gene_name": "or42b2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNQDFVGNGNVSTPSYFYISGFSGIPHMRYYYIFLFFIYIITVLGNSCLMSVIIMDRNLHTPKYIAVFNLSLTDICESTAVIPQLLDTFLFGNQMMPYGLCMSSMFSVLLFLAMQSLTLTVLSFDRFVAISLPLRYHMIVTQRLMLIIIAASWTLALLLMIIGAIFMSRLSFCKVIVTVNSFYCDHGPIYRSACNNNFPSSVIASLFPAVILGFPAFFIIFSYTCIAVTLFRITTPQDRQRATKTCMAHLILVAVFYVPITFTYAFWSFIDTNTRIINLSLTSALPPMLNPIIYTFMTEEFMVAVKRLFKRRNIFPSWK", "length": 319 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRK6-1", "protein_name": "Odorant receptor 106-11", "gene_name": "or80a6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILITYILILLGNGINLFIISTDRHLHKPMYILICNLAVVDVMYSSTCSTTMISVLLAEIKTVSFYSCISRTYFYHVGGFTECMALTLMAIDRLIAIRLPLRYHSIVTNSRVFLLIFLTWLAGFAVIGYVISVSDNVPYCQPIIKYVFCEYASMIRAACVDPEPYFFISAMLNMWLLCGQFPFILCTYAVLAYSVTKLANNSNKKQLINTCLSHIIVLSSFYAPKLVSTLLTRIGVVLTLTERNAILITASLVPPLINPTVYCIRTKEIRKRLSNVFLHRKTVPNP", "length": 315 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRK8-1", "protein_name": "Odorant receptor 106-9", "gene_name": "or80a11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVNETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMALDRLIAISLPLRYHSFVTNSRILWLIFLTWILSFALIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGPFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTKIGVVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKEIRRKITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRK9-1", "protein_name": "Odorant receptor 106-8", "gene_name": "or80a5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANVTYFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDKHLHKPMYILICNLAVVDMMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTESMALTLMALDRLIAINLPLRYNSFVTNSRILWLVFLTWILSFAVIGFLIYVTDSLTYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTMYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYVPKIVYILLTRIGLVLTLTERNAVVIVSCYVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 314 }, "evidence": [ { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRL0-1", "protein_name": "Odorant receptor 106-7", "gene_name": "or80a7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANDNYTVKKIDNFMITGFDHLQNQKLLGFLILISYMFILLGNGINLCIISTNRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEVKTVSYYSCISRTYFYHLGDLTECMALTLMAIDRIIAIKLPLRYHSIVTNVRIVLLIFLAWLICFVAVGFLTYVADSLTYCQPVIKYVFCSYSALVRFSCVDPEPYFAISTIFSMWPLCGQFPFILCTYAFLAYSVTKLSNSSRKQMINTCLSHIIVLLSYFAPKIVYILLTRIGVVLTLTERNAIMIVSSLVPPLINPTVYCTRTKEIRKRLLDIFLRKKIAPNHLKISSVNLLS", "length": 325 }, "evidence": [ { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRL1-1", "protein_name": "Odorant receptor 106-6", "gene_name": "or80a3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANATYFVKNVDSFIITGFDHLQNQKILGSLILITYILILLGNGINLCVISTNRHLHKPMYILICNLAVVDIMYTSACSTTMISVLLAEIKTVSYYSCISRMFFYTLGDLTECMALTLMAIDRVIAIRLPLRYHSIVTNSRILWLIFLTWMFCFAAIGYLILLADSLPYCQPVIKYIYCSYAAVVRAACVDPEPYFAITTIYSMVPLCGQFPFILCTYAVLAYSVTKLSNSSRKQMINTCLSHIIVLLSFYVPKIVYILLTRIGVVLTLTERNAIAIVSSLVPPLINPTVYCTRTKEIRKRVSDVFLHSKKIVPRDFKSFPNTLSS", "length": 326 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRL2-1", "protein_name": "Odorant receptor 106-5", "gene_name": "or80a9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETYMKNVDSFIITGFDHLQNQKLLGSLILISYMFILIGNIINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKMVSYYSCITRTFFYHVADIAECMALTLMAIDRVVAIRLPLRYHSIVTNLRTFCFIFVTWLMGFAAVGFFTSVLDKSPYCQPLIKYAFCSYSSLVRAACVDPEPYFVISTIYSMVPLCGLFPFVMCTYAFLAYSVTKLSNSSRKQMINTCLSHLIVLLSYYAPKVVTILLTRIGVVLTVTDRNAILIAASLVPPLINPTVYCTRTKEIRRRLSDFFLSTKILPNNFK", "length": 316 }, "evidence": [ { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRL3-1", "protein_name": "Odorant receptor 106-4", "gene_name": "or80a4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETYFVKNVDSFTITGFDHLQNQKLLGFLILISYMLILLGNGINLCIISTNRHLHKPMYILICNLALADIIYTTISSATMISVLLAEVKTVSYYSCILRMYFYHLGDLTECMALTLMAIDRVIAIRLPLRYHSIVTNSRILWLIFLTWMFCFAAIGYLILLADSLPYCQPVIKYIYCSYAAVVRAACVDPEPYFAISTIYSMVPLCGQFPFILCTYAVLAYSVTKLSNSSRKQMINTCLSHLIVLLCCYAPKVVSYLLTRIGVVLTLTERNAILIVVSLVPSLINPIVYCSRTKEIRKILSDVLMRKKISPSNF", "length": 316 }, "evidence": [ { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRL4-1", "protein_name": "Odorant receptor 106-3", "gene_name": "or80a8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAENSTMKNIDSFIITGFDHLQNQKLLGSLILITYILILLGNGINLCIILADKHLYKPMYILMCNLAVVDIIYTSTCSTTMISVLLAEDKTVSYYSCISRMFFYHLGDYTICLALTLMAIDRLIAIKLPLRYHSIVTNSQTLLFIVLTWIIAIAIMGVLTSIIDNAPYCQPIIKYVFCDYPSMIRAACVNPEPYFFLPAMINLWFFCGLLPFVICTYAVLAYSVTKLSNSSRKQMINTCLSHLIVLFSFYAPKLVSYLLTRIGVVLTLTERNAILIISSLLPALINPVVYCTRTKEIRKRLADVFLHKKVVPGQFKVIS", "length": 320 }, "evidence": [ { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRL5-1", "protein_name": "Odorant receptor 106-2", "gene_name": "or80a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAENYSVRNVDSFIITGFDHLQNQTLLGSLILITYILILLGNGINLFIILSDRHLHKPMYILMCNLAVVDIIYTSTCSTTMISVLLADVKTVSYYSCISRMFFYSLGDLTICMALTLMAIDRLIAIRLPLRYHSIVTNSQTFFFILLTWIIAIALIGVMTSAVDNAPYCQPVIRYVFCEYASMIRAACVNPEPYFFLPSMINLWWFCGLFPFVMCTYAVLAYSVTKLSNSSRKQMINTCLSHLIVLLCFYAPKLVSNVLTRIGVVLTLTDRNAILIISSLLPALINPVVYCTRTKEIRKRLADVFLHKKIVPGHFKVIS", "length": 320 }, "evidence": [ { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRL6-1", "protein_name": "Odorant receptor 106-1", "gene_name": "or80a13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGNYTVNNVDSFIITGFDHLQNQKLLGSLILITYILVLLGNGINLCVISTNRHLHKPMYILICNLAVVDVMYSSTCSTTMISVLLADVKTVSYYSCISRMFFYHIGDFTECMALTLMAIDRLIAIRLPLRYHSIVTNSRTFLFIVLTWVIAIALMGVLTSAVDNAPYCQPVIKYVFCDYPSMIRAACVNPEPYFFLPAMINLWWFCGLFPFVMCTYAVLAYSVTKLSNNSSRKQMINTCLSHLVVLLSYYAPKIVSALLTRIGVVLTLTERNAILIISSLIPPLINPTVYCTRTKEIRKRLADVFLHRKVAPNNLKVLA", "length": 319 }, "evidence": [ { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRM3-1", "protein_name": "Olfactory receptor", "gene_name": "or41a1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQNAISSGQNSSIIQPAGFYIVALSSVPYSNVYVMFLTVLYVITVICNVFLISIIVYDQRLHVPKFMAVGNLAVVDLILSTSLVPGMIKIYIVLDNFMPFKLCLVQMYTYYTFLKVEALSLCILSYDRFIAICFPLRHESINTNTRMTYIICVSWFLSFSISLYGTLSIPALSFCGSLQVNSYFCDYAPVLRVACSDTASQFNFGTASNILFVIIPFAFIFLTYAGILYAVFRMKNNQSRFKALATCTEHLILVALFFFPIVIIFSLGLFGYIINSNVRSVCLSMTSLLTPCVNPILYSLKTKEIRSRVYFLLPQRLSVHPLKSAQ", "length": 326 }, "evidence": [ { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRM4-1", "protein_name": "Olfactory receptor", "gene_name": "or41a3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQNINSSIIQPAGFYIVALSSVPYSNVYVMFLTVLYVITVICNVFLMSIIVYDQRLHVPKFMAVGNLAVVDLILSTSLVPGMIKIYIVLDNFMPFKLCLVQMYTYYTFLELETLSLCILSYDRFIAICFPLRHESINTNTRMTYIICVSWFLSFSISLYGTLSIPALSFCGSLQVNSYFCDYAPVLRVACSNTTSQWNFATILSILFLAVPLCFIFLTYMFILYAVFRMNNNQRRFKALATCTEHLILVSLYFFPIAIIFSLGFFGVIINPSVRTVCLSLSSVLPPCANPVIYSLKTKEIRSKIVSLLNLRLSVHPLKNVH", "length": 321 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2PRM5-1", "protein_name": "Odorant receptor 106-12", "gene_name": "or80a2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANENYTVKNVDSLIITGFDHLQNQKLLGFLVLISYMLILLGNGINLFIILTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLIAEIKTVSYYSCISRTYFYHLGGFTECMALTLMAIDRLIAIRLPLRYHSIVTNSRVFLLIFLTWLAGFAVIGYVISILDNVPYCQPIIKYVFCEYASMIRAACVDPEPYFFIPAMLNMWLLCGQFPFILCTYAVLAYSVTKLANNSSKKQMINTCLSHIIVLSSFYAPKLVSSLLTRIGVVLTLTERNAILITASLVSPLINPTVYCTRTKEIRKRLANVFLHRKTVPNPLKSISKGSSS", "length": 326 }, "evidence": [ { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZMA0-1", "protein_name": "Olfactory receptor", "gene_name": "Or12d17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MENSTSVDEFLLLGLTTVQKLQPIFFVMFLTIYLLNLVGNGVILMIVTLERRLHSPMYFFLGNLSCLDICYSSVTLPKVLINLLSRHRTISFLGCITQLYFFHFLGSTEAILLAVMAFDRFVAICSPLRYTAIMNPQLCILLAATAWLTSFFYALLHSVMTAHLNFCHSHKLSHFFCDVKPLLEVACGSTVLNQWLLSVVTGSISMGAFLLIVLSYFYIIAFLLFKNRSCRMLRKALSTCTSHFMVVCLFYGPVGFTYIRPATASASSMSEDRMVAIIYSAVTPVLNPLIYTLRNKEVMLALKRNFGKKLFKDNQLHAGDQ", "length": 321 }, "evidence": [ { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TQQ0-1", "protein_name": "Olfactory receptor 4E2", "gene_name": "Or4e2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGALNQTRVTEFIFLGLTDNWVLEILFFVPFTVTYMLTLLGNFLIVVTIVFTPRLHNPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCIAQLFFLHLFACSEIFLLTIMAYDRYVAICIPLHYSNVMNMKVCVQLVFALWLGGTIHSLVQTFLTIRLPYCGPNIIDSYFCDVPPVIKLACTDTYLTGILIVSNSGTISLVCFLALVTSYTVILFSLRKQSAEGRRKALSTCSAHFMVVALFFGPCIFLYTRPDSSFSIDKVVSVFYTVVTPLLNPLIYTLRNEEVKTAMKHLRQRRICS", "length": 308 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TRT7-1", "protein_name": "Olfactory receptor family 12 subfamily J member 4", "gene_name": "Or12j4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPVNQSVVTMFILQRFVDDPRVQDVLFCLFFALFVAAIAGNGLIIATIHSSPNLHTPMYFFLVNLALMDVICTVTVLPKVLQSLVAENSISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRPLHYGTLMSGRVCVALATFVWFTGAFNSLVLTCLMLPLSFCGPNLITHFFCEIPSVLILSCSPTFINDIMTVIADMFLTGLNFLLTMTSYGFIISSILRIRSAEGKKRAFSTCSAHLVVVTLYYSTVLYTYVRPALGTAGFLDKLIAVLYTTVTPSLNPLIYTLRNKEFKTSFKKLISLLRTLSLEMNSKSNG", "length": 320 }, "evidence": [ { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TRT9-1", "protein_name": "Olfactory receptor family 12 subfamily J member 2", "gene_name": "Or12j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMNGTLVTEFLILGFSEMPHLRVPLLFSFLCLYMAAISGNLLIMVTISASPALHTPMYFFLVNLAIVDILCTSTILPKLLDSMMTGRTISYGGCMAQLFFFTWSLGAELLLFSAMAYDRFVAICCPLHYSAWMGPRVCAFLAGIVWTISLTNTSVHTGLMLRLPFCSSNVIEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVTILSYGFIVASILKIRSAEGKRRAFSTCSAHLIVVTMYYSTVIYTYIRPSSSYSLNKDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLLSCC", "length": 305 }, "evidence": [ { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TRV9-1", "protein_name": "Olfactory receptor", "gene_name": "Or10aa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDHVNYTWTRTFILAGFTTSGALRPLAFLGTLCIYLLTLAGNLFIIVLVQADSGLSTPMYFFISVLSFLELWYVSTTVPTLLHTLLHGHSPIPSSACFVQLYVFHSLGMTECYLLGVMALDRYLAICRPLHYHALMSRQVQLWLAGATWVAGFSAALVPACLTASLPYCLKEIAHYFCDLAPLMRLACVSTRWHARVHGAVIGVATGCNFVLILGLYGGILTAVLKLPSAASRAKAFSTCSSHMTVVALFYASAFTVYVGSPQSRPEGTDKLIALVYALLTPFLNPIIYSLRNKEVKEAVKRVSEKIRTLLRDT", "length": 314 }, "evidence": [ { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TRX4-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGKNQTVISRFILLGLPIPPEHQHLFYALFLAMYLTTVLGNLVIIVLIHLDSHLHTPMYLFLSNLSFTDLCFSTVTMPNFLQNMQSQVSSIPYAGCLAQMYFFLFFGDVESLLLVAMAYDRYVAICFPLHYTRIMSPNLCVSMVLLSWALTTLCAMLHTLLLTRLSFCKNNVIPHFFCDLSALLKLACSDIHINELMIMIIGALVVILPFLLIIVSYAHIVSSILKVPSTRGIHKVFSTCGSHLSVVSLFYGSVIVLYLCPSSNNSTVKDTVMSMMYTVVTPMLNPFIYSLRNRDMKEALKRVLQKKIKLSSNYGNYISDVFIK", "length": 325 }, "evidence": [ { "id": "RGD:1333253", "url": "https://alliancegenome.org/gene/RGD:1333253#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TRX7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGNNQTLISKFLLLGLPILSEYHFLFYALFLAMYLTTILGNLLIIALVRLDSHLHTPMYLFLSNLSFSDLCFSSVTIPKLLQNMQSQVPSISYVGCLTQLYFFMVFGDMESFLLVVMAYDRYVAICFPLHYTSIMSTKFCTSLVLLLWMLTTSNALMHTLLMARLSFCEKNVILRFFCDISALLKLSCSDTFVNELMIFIMGGIIIIIPFLLIVMSYVRIFFSILKVPSTQGIHKVFSTCGSHLSVVSLFYGTIIGLYLCPSSNNSTVKESAMAMMYTVVTPMLNPFIYSLRNRDMKRALIRVICSKKISL", "length": 312 }, "evidence": [ { "id": "RGD:1592971", "url": "https://alliancegenome.org/gene/RGD:1592971#orthology", "database": "AGR" }, { "id": "RGD:1334013", "url": "https://alliancegenome.org/gene/RGD:1334013#orthology", "database": "AGR" }, { "id": "RGD:1333178", "url": "https://alliancegenome.org/gene/RGD:1333178#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TRX8-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIINNQTAIPQFILLGLPILPEQQQMFYALFLAMYLTTVLGNLIIIILIRLDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNIQSQDPSISYAGCLTQMYFFMVFANTENVLLVVMAYDRYVAICFPLHYTSIMSPKLCVSLVVLTWVFTVLYSMLHTLLLARLSFCEDNVITHFFCDISALLKLACSDTYINELMIFILGTLDTVVPFLLIVVSYVQIVCSILKFSTKQGIAKVFSTCGSHLSVVSLFYGTIIGVYLCPSANNSTVKEIVMALMYTVVTPMLNPFIYSLRNRDIKEALIRVLCKKQIPL", "length": 312 }, "evidence": [ { "id": "RGD:1333517", "url": "https://alliancegenome.org/gene/RGD:1333517#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TRX9-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEGNQTVIFQFLLLGLPIPTEHQQLYYALFLLMYLTTVLGNLIIIILIRLDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDSSITYAGCLTQMYFFLLFGDLESFLLVAMAYDRYVAICFPLHYMSIMSPSLCVSLVLLSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTHVNELVIFVTGGLILVIPFVLILVSYAQIVSSILKVPSARGIRKAFSTCGSHLSVVSLFYGTIIGLYLCPSADNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDMKGALARVICKKKVFFCL", "length": 314 }, "evidence": [ { "id": "RGD:1333989", "url": "https://alliancegenome.org/gene/RGD:1333989#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TS01-1", "protein_name": "Olfactory receptor family 13 subfamily G member 1", "gene_name": "Or13g1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMNFSIVSEFMILGLTQKSELQGILFIVFLFIYLVALLGNMLIVVAIIYNTTLHTPMYILLLALAVVDIICTTSIIPKMLGTMLTSKNSISYGGCMSQLFFFTWSLGAEMVLFTTMAYDRYVAICFPLRYSTIMNHYTCVGLLSIVMAIAVTNSWVHTGLILRLTFCGPNIIDHFFCEIPPLLALSCSPVRVNEVMVYVADITLAVGDFTLTCISYGFIIAAILRIRTTEGKKKAFSTCSSHLMVVSLYYSPVIYTYIRPASSYTFDKDKVVAALYTLVTPTLNPIVYSFRNKEMQSGIKKVFAFLKG", "length": 308 }, "evidence": [ { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NGC2-1", "protein_name": "Olfactory receptor 4E2", "gene_name": "OR4E2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSLNQTRVTEFVFLGLTDNRVLEMLFFMAFSAIYMLTLSGNILIIIATVFTPSLHTPMYFFLSNLSFIDICHSSVTVPKMLEGLLLERKTISFDNCITQLFFLHLFACAEIFLLIIVAYDRYVAICTPLHYPNVMNMRVCIQLVFALWLGGTVHSLGQTFLTIRLPYCGPNIIDSYFCDVPLVIKLACTDTYLTGILIVTNSGTISLSCFLAVVTSYMVILVSLRKHSAEGRQKALSTCSAHFMVVALFFGPCIFIYTRPDTSFSIDKVVSVFYTVVTPLLNPFIYTLRNEEVKSAMKQLRQRQVFFTKSYT", "length": 313 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGW6-1", "protein_name": "Olfactory receptor 6K6", "gene_name": "OR6K6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKQYSVGNQHSNYRSLLFPFLCSQMTQLTASGNQTMVTEFLFSMFPHAHRGGLLFFIPLLLIYGFILTGNLIMFIVIQVGMALHTPLYFFISVLSFLEICYTTTTIPKMLSCLISEQKSISVAGCLLQMYFFHSLGITESCVLTAMAIDRYIAICNPLRYPTIMIPKLCIQLTVGSCFCGFLLVLPEIAWISTLPFCGSNQIHQIFCDFTPVLSLACTDTFLVVIVDAIHAAEIVASFLVIALSYIRIIIVILGMHSAEGHHKAFSTCAAHLAVFLLFFGSVAVMYLRFSATYSVFWDTAIAVTFVILAPFFNPIIYSLKNKDMKEAIGRLFHYQKRAGWAGK", "length": 343 }, "evidence": [ { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGY3-1", "protein_name": "Olfactory receptor 6K3", "gene_name": "OR6K3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MCWTMPSPFTGSSTRNMESGNQSTVTEFIFTGFPQLQDGSLLYFFPLLFIYTFIIIDNLLIFSAVRLDTHLHNPMYNFISIFSFLEIWYTTATIPKMLSNLISEKKAISMTGCILQMYFFHSLENSEGILLTTMAIDRYVAICNPLRYQMIMTPRLCAQLSAGSCLFGFLILLPEIVMISTLPFCGPNQIHQIFCDLVPVLSLACTDTSMILIEDVIHAVTIIITFLIIALSYVRIVTVILRIPSSEGRQKAFSTCAGHLMVFPIFFGSVSLMYLRFSDTYPPVLDTAIALMFTVLAPFFNPIIYSLRNKDMNNAIKKLFCLQKVLNKPGG", "length": 331 }, "evidence": [ { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGZ3-1", "protein_name": "Olfactory receptor 13G1", "gene_name": "OR13G1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNHSVVTEFIILGLTKKPELQGIIFLFFLIVYLVAFLGNMLIIIAKIYNNTLHTPMYVFLLTLAVVDIICTTSIIPKMLGTMLTSENTISYAGCMSQLFLFTWSLGAEMVLFTTMAYDRYVAICFPLHYSTIMNHHMCVALLSMVMAIAVTNSWVHTALIMRLTFCGPNTIDHFFCEIPPLLALSCSPVRINEVMVYVADITLAIGDFILTCISYGFIIVAILRIRTVEGKRKAFSTCSSHLTVVTLYYSPVIYTYIRPASSYTFERDKVVAALYTLVTPTLNPMVYSFQNREMQAGIRKVFAFLKH", "length": 307 }, "evidence": [ { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VF79-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIMNNKTVISQFILLGLPIPQEYQHLYYALFLAMYLTTVLGNLIIIILIILDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDTSISYAGCLTQMYFLLVFGDLESILLLVMAYDRYVAVCFPLHYMSIMSPTLCVCLLVLSWVFTVLYSMLHTLLLSRLSFCEDNLIHHFFCDISALLKLACSDIHINELMIFIMGGLVSIIPFLLIVVSYIQIVYSILKISSAHVLHKIFSTCGSHLSVVSLFYGTIFALYLCPSANNSTVKEISMAMMCTVVTPMLNPFIYSLRNRDMRDALFGVLGKKKISL", "length": 312 }, "evidence": [ { "id": "RGD:1333644", "url": "https://alliancegenome.org/gene/RGD:1333644#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFE8-1", "protein_name": "Olfactory receptor family 12 subfamily J member 3", "gene_name": "Or12j3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALVNQSVVTMFILQRFVDDPWIQDVLFCLFFALFMAAIAGNGLIIATIHSSPNLHTPMYFFLVNLSLMDVICTVTVLPKVLQSLVAENSISYGGCLTQMFVFSWVLGSELLLFSAMAYDRYLAICRPLHYGTLMSGKVCVALATFVWFTGALNSLVLTCLMLPLSFCGPNLITHFFCEIPSVLILSCSPTFINDIMTVITDMFLTGLNFLLTMTSYVFIIASILRIRSAEGKKRAFSTCSAHLVVVTLYYSTVLYTYVRPALGTAGFLDKLIAVLYTTVTPSLNPLIYTLRNKEFKISFKKLLFPH", "length": 307 }, "evidence": [ { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFY0-1", "protein_name": "Olfactory receptor family 1 subfamily JRmember 1", "gene_name": "Or1r1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVTNLTYKPQFQLLGLMDGTDPHPLLFLLFLSIYLLNALGNLSMVVLVRSDGALCSPMYYFLGHLSLVDVCFTTVTVPRLLATLLHPGQAISFQACFAQMYFFVALGITESYLLAAMSYDRAVAVCRPLHYGAVMTPWRCFLLVAASWAVAHLHSLLHTLLISALTYPPSAPVRHFFCDMTVMLSLATSDTSAAETAIFSEGLTVVLTPLLLVSLSYARILVAVLGIRTTGGRHRVFSTCGAHLVVVSLFFGSVLSVYFRPSSAYSARYDRMASVVYAVVTPTLNPFIYSLRNKEVKSALKRGFRWRAAPQDE", "length": 314 }, "evidence": [ { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VG96-1", "protein_name": "Olfactory receptor", "gene_name": "Or12d17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENSTSVDEFLLLGLTSVQKLQPIIFVMFLTIYLLNLVGNGVILMIVTLERRLHSPMYFFLGNLSCLDICYSSVTLPKVLINLLSRRRAISFLGCITQLYFFHFLGSTEAILLAVMAFDRFVAICSPLRYTAIMNPQLCILLAATAWFTSFFYALLHSVMTAHLNFCHSHKLSHFFCDVKPLLEVACGNTVLNQWLLSVVTGSISMGAFLLILLSYFYIIAFLLFKNRSCRMLKKALSTCTSHFMVVCLFYGPVGFTYIRPATASASSMSEDRVVAIIYSAVTPVLNPLIYTLRNKEVMLALKKNFGKKLFKGN", "length": 314 }, "evidence": [ { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VGI1-1", "protein_name": "Olfactory receptor 1E16", "gene_name": "Or1e16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTERNKTVISQFLLLGLPIPPEHQQLFYALFLVMYLTTVLGNLIIIILIILDSHLHTPMYLFLSNLSFSDLCFSSVTMPKLLQNMQSQVPSIPYAGCLAQIYFFLFFGDLGNFLLVAMAYDRYVAICYPLHYTTIMSPRLCVSLVVLSWVLTTFHAMLHTLLMARLSFCEDNVIPHYFCDMSALLKLACSDTRVNEVVIFIVASIFLVLPFALITMSYVRIVSSILKVPSSQGIYKAFSTCGSHLSVVSLFYGTVIGLYLSPSSNNSTVKDTVMSLMYTVVTPMLNPFIYSLRNRDIKGALERVFCKRKIQLNL", "length": 314 }, "evidence": [ { "id": "RGD:1359186", "url": "https://alliancegenome.org/gene/RGD:1359186#orthology", "database": "AGR" }, { "id": "RGD:1333012", "url": "https://alliancegenome.org/gene/RGD:1333012#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VGI2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGTTERNQTAISQFLLLGLPIPTEHQHLFYALFLAMYLTTVLGNLIIIILIHLDSHLHTPMYSFLSNLSFSDLCFSSVTMPKLLQNMQSQDPSIPYAGCLAQMYFFLFFADLESFLLVAMAYDRYVAICFPLHYMSIMSPRLCVSLVLLSWVLTTFHAMLHTLLMARLSFCEDNVIPHFFCDMSALLKLSCSDTYVNELVIFVMGSLILVIPFVLILVSYARIVSSILKVPSARGIRKAFSTCGSHLSVVSLFYGTVIGLYLCPSADNSTVKETVMAMMYTVVTPMLNPFIYSLRNRDMKGALISVLCKKKILFCL", "length": 317 }, "evidence": [ { "id": "RGD:1334228", "url": "https://alliancegenome.org/gene/RGD:1334228#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VGL2-1", "protein_name": "Olfactory receptor family 2 subfamily J member 6", "gene_name": "Or2j6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNGTLVTEFLILGFSDMPHLRILLFLSFLCLYMAAVSGNLLIMVTISASPTLHTPMYFFLVNLAVVDILCTSTILPKLLDTMVGGRTISYGGCMAQLFFFTWSLGVELLLFSAMAYDRFVAICCPLHYSTWMGPRVCAFLAGIVWAISLTNTSINSSLVLRLPFCSSNVVEHFFCEIPPLLKLSCAPTQLNEAMAFAADVFLAVGNFSVIILSYGFIVASILKIRSAEGKQRAFSTCSAHLIVVTMYYSTVIYTYIRPSSSYSLNKDKVVSIIYTSVAPTLNPLIYTLRNKDVKVALRRLFSCC", "length": 304 }, "evidence": [ { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VGR3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGKNQTLILEFLLLGLPISSEYHLLFYALLLAMYLTTLLGNLLIILLVRLDSHLHTPMYLFLSNLSFSDLCFSSVTIPKLLQNMQSQVPTISYADCLTQLYFFMVFGDMESFLLVVMAYDRYVAICFPLHYTSIMSTKFCALLVLLLWMLTISHALLHTLLMARLSFCEKNVILHFFCDISALLKLSCSDTYVNELMIFIMGGIISIIPFLLIVMSYVRIFFSILKVPSSQDIHKVFSTCGSHLSVVTLFYGTIIGLYLCPSGNNSTVNEISMAMMYTVVTPMLNPFIYRLRNRDMKRALIRVIFSKKISL", "length": 312 }, "evidence": [ { "id": "RGD:1592971", "url": "https://alliancegenome.org/gene/RGD:1592971#orthology", "database": "AGR" }, { "id": "RGD:1334013", "url": "https://alliancegenome.org/gene/RGD:1334013#orthology", "database": "AGR" }, { "id": "RGD:1333178", "url": "https://alliancegenome.org/gene/RGD:1333178#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VGT1-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIKNNQTVISQFLLLGLPIPPEHQHLFYALFLAMYLTTVLGNLIIIILIILDFHLHTPIYLFLSNLSFSDLCFSSVTMPKLLQNMQSQDTTISYVGCLTQMYFPNVFANLENFLLMFMAYDRYVAICYPLRYTSIMSPILCVCMVFMSWLLTMLNSTLHTVLIVKLSFCEDNVIPHFFCDISAVLKLACSDIYINELTIFITGAFIIVIPFLLIVVSYVQIVCSILKFSSTRGIAKIFSTCGSHLSVVSLFYGTIIGLYLCPSTNNSTVKDTAMAMMYTVVTPMLNPFIYSLRNKDMKEALIRVLCKKEISL", "length": 312 }, "evidence": [ { "id": "RGD:1333088", "url": "https://alliancegenome.org/gene/RGD:1333088#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VGT2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1e19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRRNQTVISQFLLLGLPIPPEHQQLYYALLLSMYLTTVLGNLIIIILILLDSHLHTPMYLFLSNLSFADLCFSSVTMPKLLQNMQSKVPSIPYAGCLAQIYFFLYFGDLGNFLLVAMAYDRYVAICFPLHYMSIMSPRLCVSLVLLSWVLTTFHAMLHTLLMARLSFCEDNVIPHYFCDMSTLLKVACSDTHDNELAIFILGGPIVVLPFLLIIVSYARIVSSIFKFPSFQGIRKAFSTCGSHLSVVSLFYGTVIGLYLCPSANNTYVKETIMSLMYTMVTPMLNPFIYSLSNRDIKDALEKIMCKRQIPFFL", "length": 314 }, "evidence": [ { "id": "RGD:1333590", "url": "https://alliancegenome.org/gene/RGD:1333590#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WZA6-1", "protein_name": "Olfactory receptor 1E3", "gene_name": "OR1E3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMKKNQTMISEFLLLGLPIQPEQQNLFYALFLAVYLTTLLGNLLVIVLIRLDSHLHMPMYLCLSNLSFSDLCFSSVTMPKLLQNMQSQNPSIPFADCLAQMYFHLFYGVLESFLLVVMAYHCYVAICFPLHYTTIMSPKCCLGLLTLSWLLTTAHATLHTLLMARLSFCAENVIPHFFCDTSTLLKLACSNTQVNGWVMFFMGGLILVIPFLLLIMSCARIVSTILRVPSTGGIQKAFSTCGPHLSVVSLFYGTIIGLYLCPLTNHNTVKDTVMAVMYTGVTHMLNPFIYSLRNRDMRGNPGQSLQHKENFFVFKIVIVGILPLLNLVGVVKLIMKYHSKSVA", "length": 343 }, "evidence": [ { "id": "RGD:1592971", "url": "https://alliancegenome.org/gene/RGD:1592971#orthology", "database": "AGR" }, { "id": "RGD:1333854", "url": "https://alliancegenome.org/gene/RGD:1333854#orthology", "database": "AGR" }, { "id": "RGD:1332757", "url": "https://alliancegenome.org/gene/RGD:1332757#orthology", "database": "AGR" }, { "id": "RGD:1359186", "url": "https://alliancegenome.org/gene/RGD:1359186#orthology", "database": "AGR" }, { "id": "RGD:1333088", "url": "https://alliancegenome.org/gene/RGD:1333088#orthology", "database": "AGR" }, { "id": "RGD:1333644", "url": "https://alliancegenome.org/gene/RGD:1333644#orthology", "database": "AGR" }, { "id": "RGD:1334013", "url": "https://alliancegenome.org/gene/RGD:1334013#orthology", "database": "AGR" }, { "id": "RGD:1333178", "url": "https://alliancegenome.org/gene/RGD:1333178#orthology", "database": "AGR" }, { "id": "RGD:1332851", "url": "https://alliancegenome.org/gene/RGD:1332851#orthology", "database": "AGR" }, { "id": "RGD:1333517", "url": "https://alliancegenome.org/gene/RGD:1333517#orthology", "database": "AGR" }, { "id": "RGD:1332981", "url": "https://alliancegenome.org/gene/RGD:1332981#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q920Y8-1", "protein_name": "Olfactory receptor", "gene_name": "Or12d13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNQTSVTEFILLGVRDIQEPQPFLFAIFFTIYFVNITGNGAILMIVILDPRLHSPMYFFLGNLACLDISYSTVTVPKMLENLLSTNKAISLLGCITQLHFFHFLGTTESLLLAVMAFDRFVAICRPLHYSVIMNWQVCILMAVTIWTIAFLHALLHSVMTSRLSFCGLNHIHHFFCDVKPLLELACGNTELNLWLLNTVTGTIASVPFFLTFLSYFYIITYLFLKTRSCSMLHKALSTCASHFMVVVLFYAPVLFTYIRPTSGSSLDQDRIIAIMYSVVTPALNPLIYTLRNKEVRSALNRKVRRCLLLEEI", "length": 313 }, "evidence": [ { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q920Z0-1", "protein_name": "Olfactory receptor", "gene_name": "Or12d12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNQTSVTEFLLLGVTDIQELNPILFVIFFTIYFINITGNGAILMIVILDPRLHSPMYFFLGNLACLDISYSTVTVPKLLQNLLSTSKAISFLGCITQLHFFHFLGSTETMLLPVMAFDRFVAICRPLHYSVIMNHQLCIHMTVTIWTLGFFHALLHSVMTSRLSFCGPNHVHHFFCDIKPLLDLACGNTELNLWLLNTVTGTIALTSFFLIFLSYFYIITNLLLKTRSCSMLHKALSTCASHFMVVVLFYAPVLFTYIRPASGSSLDQDTIIAIMYSVVTPALNPLIYTLRNKEVRSALNRKVRRWL", "length": 308 }, "evidence": [ { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9I8Z0-1", "protein_name": "Odorant receptor 111-8", "gene_name": "or42e2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYYFAYFLTFYFQPVQNKADMSLSQNSSSVYPEYFFIIGLSGIHNSNYYYMFLCITYFVTVTGNSLVLLLIALYRSLHSPKYIGVFNLALADFGETNALIPNMMKTFLFDSQYISYNACLANMFFVHFFSTVQSFTLVVLAYDRFIAIFLPLRYHAIVNYTFMYFVFSIIWVFNASIVAFAVSLITRLSFCESNKVNGYYCDYGPVYRLACNDNSICASMAQLSAALYVVAPVIIIVLSYLGIFLALSKITTWEGRLKALKTCVSHLLLVGSFFLPIICIFIATSTNSLSLNARVISTSLAHALPPMLHPIIYVLNTAEIKDIIIKIVRNKCLPVRKNILKLRK", "length": 344 }, "evidence": [ { "id": "MGI:3031343", "url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": 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"url": "https://alliancegenome.org/gene/MGI:3031343#orthology", "database": "AGR" }, { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8297", "url": "https://alliancegenome.org/gene/HGNC:8297#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "RGD:1333957", "url": "https://alliancegenome.org/gene/RGD:1333957#orthology", "database": "AGR" }, { "id": "RGD:1332672", "url": "https://alliancegenome.org/gene/RGD:1332672#orthology", "database": "AGR" }, { "id": "RGD:1333297", "url": "https://alliancegenome.org/gene/RGD:1333297#orthology", "database": "AGR" }, { "id": "RGD:1333199", "url": "https://alliancegenome.org/gene/RGD:1333199#orthology", "database": "AGR" }, { "id": "RGD:1333058", "url": "https://alliancegenome.org/gene/RGD:1333058#orthology", "database": "AGR" }, { "id": "RGD:1333923", "url": "https://alliancegenome.org/gene/RGD:1333923#orthology", "database": "AGR" }, { "id": "RGD:1334073", "url": "https://alliancegenome.org/gene/RGD:1334073#orthology", "database": "AGR" }, { "id": "RGD:1334051", "url": "https://alliancegenome.org/gene/RGD:1334051#orthology", "database": "AGR" }, { "id": "RGD:1334407", "url": "https://alliancegenome.org/gene/RGD:1334407#orthology", "database": "AGR" }, { "id": "MGI:3030365", "url": "https://alliancegenome.org/gene/MGI:3030365#orthology", "database": "AGR" }, { "id": "MGI:3030232", "url": "https://alliancegenome.org/gene/MGI:3030232#orthology", "database": "AGR" }, { "id": "MGI:2177489", "url": "https://alliancegenome.org/gene/MGI:2177489#orthology", "database": "AGR" }, { "id": "MGI:3030266", "url": "https://alliancegenome.org/gene/MGI:3030266#orthology", "database": "AGR" }, { "id": "MGI:3030267", "url": "https://alliancegenome.org/gene/MGI:3030267#orthology", "database": "AGR" }, { "id": "MGI:2177487", "url": "https://alliancegenome.org/gene/MGI:2177487#orthology", "database": "AGR" }, { "id": "MGI:3030361", "url": "https://alliancegenome.org/gene/MGI:3030361#orthology", "database": "AGR" }, { "id": "MGI:3030143", "url": "https://alliancegenome.org/gene/MGI:3030143#orthology", "database": "AGR" }, { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:15033", "url": "https://alliancegenome.org/gene/HGNC:15033#orthology", "database": "AGR" }, { "id": "HGNC:14999", "url": "https://alliancegenome.org/gene/HGNC:14999#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "HGNC:8178", "url": "https://alliancegenome.org/gene/HGNC:8178#orthology", "database": "AGR" }, { "id": "HGNC:15030", "url": "https://alliancegenome.org/gene/HGNC:15030#orthology", "database": "AGR" }, { "id": "HGNC:8226", "url": "https://alliancegenome.org/gene/HGNC:8226#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9R0K4-1", "protein_name": "Olfactory receptor", "gene_name": "Or4e1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKAVLINETSVMSFRLTGLSTNPLVQMAVFFIFLIFYVLTLVGNILIVITIIYDRRLHTPMYFFLSNLSFIDVCHSTVTVPKMLSDTFSEEKLISFDACVVQMFFLHLFACTEIFLLTVMAYDRYVAICKPLQYMTIMNWKVCMMLAAALWTGGTIHSISLTSLTIKLPYCGPDEIDNFFCDVPQVIKLACTDTHIIEILIVSNSGLISVVCFVVLVVSYAVILVSLRQQISDGKRKALSTCAAHLTVVTLFLGHCIFIYSRPSTSLPEDKVVSVFFTAVTPLLNPIIYTLRNEDMKSALNKLIKRREK", "length": 310 }, "evidence": [ { "id": "MGI:3031342", "url": "https://alliancegenome.org/gene/MGI:3031342#orthology", "database": "AGR" }, { "id": "HGNC:8296", "url": "https://alliancegenome.org/gene/HGNC:8296#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UGF7-1", "protein_name": "Olfactory receptor 12D3", "gene_name": "OR12D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENVTTMNEFLLLGLTGVQELQPFFFGIFLIIYLINLIGNGSILVMVVLEPQLHSPMYFFLGNLSCLDISYSSVTLPKLLVNLVCSRRAISFLGCITQLHFFHFLGSTEAILLAIMAFDRFVAICNPLRYTVIMNPQVCILLAAAAWLISFFYALMHSVMTAHLSFCGSQKLNHFFYDVKPLLELACSDTLLNQWLLSIVTGSISMGAFFLTLLSCFYVIGFLLFKNRSCRILHKALSTCASHFMVVCLFYGPVGFTYIRPASATSMIQDRIMAIMYSAVTPVLNPLIYTLRNKEVMMALKKIFGRKLFKDWQQHH", "length": 316 }, "evidence": [ { "id": "MGI:2177492", "url": "https://alliancegenome.org/gene/MGI:2177492#orthology", "database": "AGR" }, { "id": "HGNC:13963", "url": "https://alliancegenome.org/gene/HGNC:13963#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070806-75", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070806-75#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD5" } ], "pmid": "" }, { "name": "olfactory receptor activity", "id": "GO:0004984", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004984", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFD5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PFD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD5" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 246, "start_aa": "Met", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P5M1-1", "uniprot_ac": "A0A8M9P5M1", "uniprot_id": "A0A8M9P5M1_DANRE", "mass": { "chemical_mass": 29995.0, "monoisotopic_mass": 29995.0 }, "refseq": { "ac": "XP_021325702", "name": "trypsin I-P1-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325702" }, "gene_names": [ { "name": "LOC560023", "type": "recommended", "evidence": [ { "id": "A0A8M9P5M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1" } ] }, { "name": "LOC560023", "type": "synonym", "evidence": [ { "id": "XP_021325702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325702" } ] } ], "protein_names": [ { "name": "trypsin", "type": "recommended", "evidence": [ { "id": "A0A8M9P5M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.4", "type": "synonym", "evidence": [ { "id": "A0A8M9P5M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1/entry#names_and_taxonomy" } ] }, { "name": "trypsin I-P1-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325702" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325702.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325702" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5M1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC560023", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1", "locus": {} } ], "crossref": [ { "id": "A0A8M9P5M1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P5M1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "560023", "url": "https://www.ncbi.nlm.nih.gov/gene/560023", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050127", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050127", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:560023", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560023", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P5M1", "url": "https://www.orthodb.org/?gene=A0A8M9P5M1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24264", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24264", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24264:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24264:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325702", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P5M1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P5M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13A3Z6", "url": "https://www.uniprot.org/uniprotkb/A0AB13A3Z6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13A3Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0AB13A3Z6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMEAVLIGTFRATILSRSAAGMAQLLWVFLVLAVMVRDAFSQRIIGGQEVVPYSIKYQVSLQVDRKHFCGGTLIQPQWVLTAAHCWRPASVIQVVLSEHNLAVEEGFEQVCTVAKVFSHVAYNPKTFNNDIMIIKLTAPAQINAYVQPALLPTADTPELAGGSSCTVSGWGVTRLYNFYLSPILRAVDVEIFSSCQLYYYYRVNDNMICAGSRFGGKDSCQGDSGGPLICDGYLEGIVSWGIGCALPYYPGVYTKVRNYNRWIDWIISTES", "length": 271, "header": "tr|A0A8M9P5M1-1|A0A8M9P5M1_DANRE Isoform 1 of trypsin OS=Danio rerio OX=7955 GN=LOC560023 PE=4 SV=2 CANONICAL=A0A8M9P5M1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P5M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1/entry#A0A8M9P5M1-1", "sequence": { "sequence": "MMEAVLIGTFRATILSRSAAGMAQLLWVFLVLAVMVRDAFSQRIIGGQEVVPYSIKYQVSLQVDRKHFCGGTLIQPQWVLTAAHCWRPASVIQVVLSEHNLAVEEGFEQVCTVAKVFSHVAYNPKTFNNDIMIIKLTAPAQINAYVQPALLPTADTPELAGGSSCTVSGWGVTRLYNFYLSPILRAVDVEIFSSCQLYYYYRVNDNMICAGSRFGGKDSCQGDSGGPLICDGYLEGIVSWGIGCALPYYPGVYTKVRNYNRWIDWIISTES", "length": 271, "header": "tr|A0A8M9P5M1-1|A0A8M9P5M1_DANRE Isoform 1 of trypsin OS=Danio rerio OX=7955 GN=LOC560023 PE=4 SV=2 CANONICAL=A0A8M9P5M1-1" }, "locus": {} }, { "isoform_ac": "A0AB13A3Z6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1/entry#A0AB13A3Z6-1", "sequence": { "sequence": "MAQLLWVFLVLAVMVRDAFSQRIIGGQEVVPYSIKYQVSLQVDRKHFCGGTLIQPQWVLTAAHCWRPASVIQVVLSEHNLAVEEGFEQVCTVAKVFSHVAYNPKTFNNDIMIIKLTAPAQINAYVQPALLPTADTPELAGGSSCTVSGWGVTRLYNFYLSPILRAVDVEIFSSCQLYYYYRVNDNMICAGSRFGGKDSCQGDSGGPLICDGYLEGIVSWGIGCALPYYPGVYTKVRNYNRWIDWIISTES", "length": 250, "header": "tr|A0AB13A3Z6-1|A0A8M9P5M1_DANRE Computationally mapped isoform of trypsin OS=Danio rerio OX=7955 GN=LOC560023 PE=4 SV=1 CANONICAL=A0A8M9P5M1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "dre:560023", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560023", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5M1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5M1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5M1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5M1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P5M1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5M1" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 271, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.21.4", "ec_name": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "3.4.21.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.21.4" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PIB6-1", "uniprot_ac": "A0A8M9PIB6", "uniprot_id": "A0A8M9PIB6_DANRE", "mass": { "chemical_mass": 50697.0, "monoisotopic_mass": 50697.0 }, "refseq": { "ac": "XP_021321971", "name": "tripartite motif-containing protein 59 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321971" }, "gene_names": [ { "name": "trim59", "type": "recommended", "evidence": [ { "id": "A0A8M9PIB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6" } ] }, { "name": "trim59", "type": "synonym", "evidence": [ { "id": "XP_021321971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321971" } ] } ], "protein_names": [ { "name": "Tripartite motif-containing protein 59 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PIB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6/entry#names_and_taxonomy" } ] }, { "name": "tripartite motif-containing protein 59 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021321971", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321971" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021321971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321971" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIB6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "trim59", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060724-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060724-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PIB6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PIB6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000079238", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000079238", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100006971", "url": "https://www.ncbi.nlm.nih.gov/gene/100006971", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047153", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047153", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100006971", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006971", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEYTPHI", "url": "https://omabrowser.org/oma/group/QEYTPHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PIB6", "url": "https://www.orthodb.org/?gene=A0A8M9PIB6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F136", "url": "https://www.orthodb.org/?gene=E7F136", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25462", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25462", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25462:SF229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25462:SF229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021321971", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321971", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PIB6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HEM1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HEM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HEM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HEM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F136", "url": "https://www.uniprot.org/uniprotkb/E7F136", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F136-1", "url": "https://www.uniprot.org/uniprotkb/E7F136-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060724-2", "url": "https://zfin.org/ZDB-GENE-060724-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSDYHILQAVKRLNNCCWRKNCLKLVMDSLEEDLTCSVCYALFTDPRVLPCSHTFCKSCLESVLQVSVNFSIWRPLRLPLKCPNCRSVVELPTNGLDALPVNVCLRAIVEKYQRESRPRSPSCPEHPGQPLNVYCVQDRKLICGFCLTIGQHQGHKIDDLQTAYVKERTDQPTFIQSLRGERWEEMNRLAEQLQMEKTRSEALVQKDREVALVFFQGLELTLAQKKEQFMQALERANVLLNQAYEPLMEQLKGLQEEHSQLQILISSMEEDQESPLEYLEKVHQLRERINTLNCTPMPTVPSLQMSPRAERFIEKHWTDVTLRDLRDGPLPEISWHSESCSTSRAQVSDQTRCWRICVCLCVIMLLLLFCLNRGTHWLSALRQAGENALSGLSQPLRDLGALFCCVLQNTGSKLQAFISTVGEHTHQRLLRFLKELHWC", "length": 440, "header": "tr|A0A8M9PIB6-1|A0A8M9PIB6_DANRE Isoform 1 of Tripartite motif-containing protein 59 isoform X1 OS=Danio rerio OX=7955 GN=trim59 PE=4 SV=1 CANONICAL=A0A8M9PIB6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PIB6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6/entry#A0A8M9PIB6-1", "sequence": { "sequence": "MSSDYHILQAVKRLNNCCWRKNCLKLVMDSLEEDLTCSVCYALFTDPRVLPCSHTFCKSCLESVLQVSVNFSIWRPLRLPLKCPNCRSVVELPTNGLDALPVNVCLRAIVEKYQRESRPRSPSCPEHPGQPLNVYCVQDRKLICGFCLTIGQHQGHKIDDLQTAYVKERTDQPTFIQSLRGERWEEMNRLAEQLQMEKTRSEALVQKDREVALVFFQGLELTLAQKKEQFMQALERANVLLNQAYEPLMEQLKGLQEEHSQLQILISSMEEDQESPLEYLEKVHQLRERINTLNCTPMPTVPSLQMSPRAERFIEKHWTDVTLRDLRDGPLPEISWHSESCSTSRAQVSDQTRCWRICVCLCVIMLLLLFCLNRGTHWLSALRQAGENALSGLSQPLRDLGALFCCVLQNTGSKLQAFISTVGEHTHQRLLRFLKELHWC", "length": 440, "header": "tr|A0A8M9PIB6-1|A0A8M9PIB6_DANRE Isoform 1 of Tripartite motif-containing protein 59 isoform X1 OS=Danio rerio OX=7955 GN=trim59 PE=4 SV=1 CANONICAL=A0A8M9PIB6-1" }, "locus": {} }, { "isoform_ac": "A0AC58HEM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6/entry#A0AC58HEM1-1", "sequence": { "sequence": "MDSLEEDLTCSVCYALFTDPRVLPCSHTFCKSCLESVLQVSVNFSIWRPLRLPLKCPNCRSVVELPTNGLDALPVNVCLRAIVEKYQRESRPRSPSCPEHPGQPLNVYCVQDRKLICGFCLTIGQHQGHKIDDLQTAYVKERTDQPTFIQSLRGERWEEMNRLAEQLQMEKTRSEALVQKDREVALVFFQGLELTLAQKKEQFMQALERANVLLNQAYEPLMEQLKGLQEEHSQLQILISSMEEDQESPLEYLEKVHQLRERINTLNCTPMPTVPSLQMSPRAERFIEKHWTDVTLRDLRDGPLPEISWHSESCSTSRAQVSDQTRCWRICVCLCVIMLLLLFCLNRGTHWLSALRQAGENALSGLSQPLRDLGALFCCVLQNTGSKLQAFISTVGEHTHQRLLRFLKELHWC", "length": 413, "header": "tr|A0AC58HEM1-1|A0AC58HEM1_DANRE Computationally mapped isoform of Tripartite motif-containing protein 59 isoform X3 OS=Danio rerio OX=7955 GN=trim59 PE=4 SV=1 CANONICAL=A0A8M9PIB6-1" }, "locus": {} }, { "isoform_ac": "E7F136-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6/entry#E7F136-1", "sequence": { "sequence": "MRGKCLYFGLTRKNCLKLVMDSLEEDLTCSVCYALFTDPRVLPCSHTFCKSCLESVLQVSVNFSIWRPLRLPLKCPNCRSVVELPTNGLDALPVNVCLRAIVEKYQRESRPRSPSCPEHPGQPLNVYCVQDRKLICGFCLTIGQHQGHKIDDLQTAYVKERTDQPTFIQSLRGERWEEMNRLAEQLQMEKTRSEALVQKDREVALVFFQGLELTLAQKKEQFMQALERANVLLNQAYEPLMEQLKGLQEEHSQLQILISSMEEDQESPLEYLEKVHQLRERINTLNCTPMPTVPSLQMSPRAERFIEKHWTDVTLRDLRDGPLPEISWHSESCSTSRAQVSDQTRCWRICVCLCVIMLLLLFCLNRGTHWLSALRQAGENALSGLSQPLRDLGALFCCVLQNTGSKLQAFISTVGEHTHQRLLRFLKELHWC", "length": 432, "header": "tr|E7F136-1|A0A8M9PIB6_DANRE Computationally mapped isoform of Tripartite motif-containing protein 59 isoform X1 OS=Danio rerio OX=7955 GN=trim59 PE=4 SV=1 CANONICAL=A0A8M9PIB6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 300, "start_aa": "Thr", "end_pos": 300, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr300", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100006971", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006971", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G8D1-1", "protein_name": "E3 ubiquitin-protein ligase TRIM56", "gene_name": "Trim56", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSKVSSPTLLEALSSDFLACKICLEQLHTPKTLPCLHTYCQDCLAQLDIGGQVRCPECRETVPVPPEGVAAFKTNFFVNGLLDLVKARAAGDSHSGKPTCALCPLVGGKSSGGPATARCLDCADDLCQACADGHRCSRQTHKHRVVDLVGYRAGWYDEEARERQASQCPQHPGETLCFLCQPCSQLLCKDCRLGPHIDHPCLPLAEAVRSRKPGLEELLAGVDSNLLELEATRVAEKEALALLREQAASVGTQVEEAAERILKSLLAQKQEVLGQLRALVEAAEEATRERLTKIESQEQVAKAAAAFARRVLSLGLEAEILSLEGAITQRLRQLQDTPWTSGPTRCVLPQLELHPGLEDKNCHLLRLSFEEPRQSQKDGGKVGAGTQGGDEAQSQGDDRTKTGKQGGAQPLIPKEGKAQNPPEDDEVLIERGNRPNKKKKCKGRGKSVSREPSPILRPNLEGSGPLPRPVFSWSFPTRMPGDKRSPRITGLCPYGPQEILVADEQNRVLKRFSLNGDYKGTVPVPEGCSPCSVAALQNAVAFSANAKLYLVSPEGEVQWRRSLSLAQSSHAVAAMPCGDRVAVSVAGHVEVYKKEGSLATRFIPGGKASRGQRALVFLTTSPQGNFVGSDWQQNSVVFCDGLGQVIWEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGLEKPRVTTMVDGKYLVVSLSNGTIHVFRVRFPDS", "length": 734 }, "evidence": [ { "id": "FB:FBgn0026206", "url": "https://alliancegenome.org/gene/FB:FBgn0026206#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B5DF13-1", "protein_name": "Tripartite motif-containing protein 59", "gene_name": "Trim59", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHNFEDELTCPICYSIFDDPRVLPCSHTFCRNCLENVLQASGNFYIWRPLRIPLKCPNCRSIIEIASTGIESLPVNFALRAIIEKYQQEDHPDVVTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLFKQLTDTHWTDITRLIEKLEEQKCHSEKIVQSDKEVVLQYFKELTDTLEQKKKFFLAALCDVGKMINQEYTPQIERMKEIREQQLELMTMTTSLQDESPLKFLEKIDDVRQRVQMLKQRPLPEVQPVEIYPRVSNVLKEEWSRTEIGRIKKAVIPEMRISSKRMPCSWPDKDEKEMECFKILNIAIVSLISVILMLILLFNHHIITFLNEITSICFSEVFLSVYQSLSKNLYDLKNTVCYTLYLLKEFMWKIVSC", "length": 403 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060724-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060724-2#orthology", "database": "AGR" }, { "id": "HGNC:30834", "url": "https://alliancegenome.org/gene/HGNC:30834#orthology", "database": "AGR" }, { "id": "RGD:1311956", "url": "https://alliancegenome.org/gene/RGD:1311956#orthology", "database": "AGR" }, { "id": "MGI:1914199", "url": "https://alliancegenome.org/gene/MGI:1914199#orthology", "database": "AGR" }, { "id": "A0A8M9PIB6", "url": "https://omabrowser.org/oma/group/A0A8M9PIB6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M589-1", "protein_name": "Protein PML", "gene_name": "Pml", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSAPVGGPPEKRPNPEIETEPGSTQKAPAPSGSLCQQLDPALIPTPTMPPPEEPSEDHEHSQSPAEQAIKEEFQFLRCPGCQTQAKCPKLLPCLHTLCSGCLEAPGLQCPICQAPGSANANAEALDNVFFESLQRRLAVFRQIVDAQAACTRCKELADFWCFECEQLMCGKCFDAHQWYLKHEARPLAELRDNSVREFLDSTRKSNIFCSNTNHRTPAQTNIYCRGCAKPLCCECALLDRNHSHLQCEIGKEIQQLHEELGTMTQALEEQGRTFDSAHAQMHSAIGQLDDARSDTEKQIRARVRQVIEHVQAQERELLEAVNVRYQRDYQEIAGQLGHLEAVLQRIRTGGALVKRMKLYASEQEVLDMHGFLRKALCRLRQEEPQNHKVQLRTSGFEEFKLCLQDLVSFITQRTDVAVAGRASPEAASTHPEAASAQPEAASTHPEAASAQPEAASAHPESASTPGNSTDLEQPKEVQRAQAQAMELSKTQPVAMVKSVPGAHPVPVYAFSMQGPTYREEASQTVSPMKRKCCHIDCCRKIIKMESTDENEDRLSTSSPEQPRPSTSKAISPPHPDGTSSTESTIPEKETPLPNNNHVASDAGETEERIVVISSSEDSDAENLPSHELDDSSSESSSIQLEGPNSLKALDESLAEPHLEDRTLVFFDLKIDNETQKISQLAAVNRESKFRVLIQPEAFSVYSKAVSLESGLQHFLSFLNSMHRPLLACPRLWGPGLPIFFQALNDINKLWEFQDAISGFLAVLPLIQERIPSASSFKLRNLAKTYLARNMSERSALAAVLAMRDLCCLLEVSPGLQLAQHIYSFSSLQCFASLQPLIQAQVLPQPEARLLALHNVSFLELLTAYRSNRQEGLKKYVHYLSLQTTPSSASTQIAQFLQALSAYMDGQLEGHIPAGAEGTALSLSGRAENKGCLA", "length": 934 }, "evidence": [ { "id": "FB:FBgn0026206", "url": "https://alliancegenome.org/gene/FB:FBgn0026206#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1SH50-1", "protein_name": "Tripartite motif-containing protein 59", "gene_name": "TRIM59", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHNFEDELTCPICYSIFEDPRVLPCSHTFCRNCLEDILQASGNFYIWRPLRIPLKCPNCRSIIEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYIKEKDTPQKLLDQLTDTHWTDLTHLIEKLEEQRSHLEKMVQGDKEVVLQYFKELSDTLEQKKKNFLTALCDVDNLINQECTPQIERMKEMREQQLELMTMTASLQEESPLKFLEKVDDIRQRVQLLKQRPLPEVQPVEIYPRVSQVFKEDWSRTEIGQIKELLIPEMKISSKRMPCSWPDKDVKEVEFFKILNLVIVTLISVILMLTLFFNQHVITFLNEVTSTCFAEVSLSVYQSLSNNLHDLKNILCHTLYLLKEFMSKIISH", "length": 403 }, "evidence": [ { "id": "A0A8M9PIB6", "url": "https://omabrowser.org/oma/group/A0A8M9PIB6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3IAU3-1", "protein_name": "Tripartite motif-containing protein 59", "gene_name": "Trim59", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENVLQASGNFYIWRPLRIPLKCPNCRSIIEIASTGIESLPVNFALRAIIEKYQQEDHPDVVTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLFKQLTDTHWTDITRLIEKLEEQKCHSEKMLQGDKEVVLQYFKELTDALEQKKKKFLAALCDVGKLINQEYTPQIERVKEIREQQLELMTVTTSLQDESPLKFLEKIDDVRQRVQMLKRRPLPEAKPVEIYPRVSKVLKEEWSRTEIGHIKKAVIPEMRISSRRMPCSWPDKDEKEIEFFKILNIVIVSLISVILMLILLFNQHIITFLNEITSICFSEVSLSVYQSLSNNLCDLKNMVCYPLYLLKEFMWKIVSR", "length": 403 }, "evidence": [ { "id": "A0A8M9PIB6", "url": "https://omabrowser.org/oma/group/A0A8M9PIB6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M9PH32-1", "protein_name": "Protein meiotic P26", "gene_name": "mei-P26", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTTLEEPVQAADTVDPCPPGIPNLKTVLSDDASNSSVLEDIDVSNTSSSSSSSSSSSSSSGSCSGSGTDTDTGKGSSNVGSLDVTSSSSIGSETSISSTGSTAIAGPSTLLDDSNSSGLGLVVDVDSNGSSQELSSHGVTELDSLEDSCSGLMIKDGDKLCKLCSLRLVMPRILSCLHVFCEDCLQAVVSKDTMSASSPNSCSSSSFDGSEHQNRLSAVFIECPVCKQETPLGPKGIKALPCDYIVTNILDLSNLESEHIVCTSCKSKEEAISRCNDCANFLCNGCDNAHKYMRCFENHHVVRIEDLTKNVHDKLIIHKPVFCPQHVSENLKYYCFTCQVPTCNDCLLSDHKGSDHHYETATVAEQAVRADLEETLSDTLKKADYCNDAGSNLGSALTELQSQHDTVRQQIEDAYKCYKRMLESIKDQMLNELGRLHSDRELKIMDLMQSMENTMGKLQHAAQFGQRAVDKANSIEFLLLKPIISAQCLNLMEQTPKCDINYQLQFDSKPEMFEQFAREMFGKFQTDHIDSSPKKLGMTQQLQQQQQQQQQLQQQQHQHQHQVQQQQHHHQQQQQQKQQVQHQQQQQKLQLQQQQQHQHNSNNLIVGHRGSSSVQGRLTSAVFSPISLPSSLQSSFDGDTNSVMSNFSMMDSPPQPSSQQQLPSAQQQSQQQQQQQQQQQAVVLQQVQQQQKHQQHQVQQQQQQQVLHQPTSAQSMPQQLGQLVAPQGIVQQAGHVNLNAGPGPNISINGLGAGGPPPSFSMLEYNISRLASLTETMPDTLNDALAVGGGAAGPVPNVVAQVPGGSAVTGAAVVGASHAHQQQSQAVMPASAVTPTQPITLADILSGDQRALNNLQALAKLGLNNNDDGLLLNGSSTEIDFLSDFCMPPATSPSLQSLNPIVGGVEDMGLNNFHAVAAPGTTSVVTGRNKATPMQIRCKFGSLGTAKGQFNSPHGFCLGVDEEIIVADTNNHRIEVFDKMGALKFQFGVAGKEEGQLWYPRKVAVMHNNGKFVVCDRGNERSRMQIFSKCGHFMRKIAIRYIDIVAGLAVTAKGHIVAVDSVSPTVFVISEEGELVRWFDCSDYMREPSDIAIRDNDFYVCDFKGHCVAVFQDDGTFLYRIGNEKVTCFPNGIDISNAGDVLIGDSHGNRFHVACYSREGALQSEFECPHVKVSRCCGLKITSEGYVVTLAKNNHHVLVLNTLYVH", "length": 1206 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060724-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060724-2#orthology", "database": "AGR" }, { "id": "FB:FBgn0026206", "url": "https://alliancegenome.org/gene/FB:FBgn0026206#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P29590-1", "protein_name": "Protein PML", "gene_name": "PML", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPAPARSPRPQQDPARPQEPTMPPPETPSEGRQPSPSPSPTERAPASEEEFQFLRCQQCQAEAKCPKLLPCLHTLCSGCLEASGMQCPICQAPWPLGADTPALDNVFFESLQRRLSVYRQIVDAQAVCTRCKESADFWCFECEQLLCAKCFEAHQWFLKHEARPLAELRNQSVREFLDGTRKTNNIFCSNPNHRTPTLTSIYCRGCSKPLCCSCALLDSSHSELKCDISAEIQQRQEELDAMTQALQEQDSAFGAVHAQMHAAVGQLGRARAETEELIRERVRQVVAHVRAQERELLEAVDARYQRDYEEMASRLGRLDAVLQRIRTGSALVQRMKCYASDQEVLDMHGFLRQALCRLRQEEPQSLQAAVRTDGFDEFKVRLQDLSSCITQGKDAAVSKKASPEAASTPRDPIDVDLPEEAERVKAQVQALGLAEAQPMAVVQSVPGAHPVPVYAFSIKGPSYGEDVSNTTTAQKRKCSQTQCPRKVIKMESEEGKEARLARSSPEQPRPSTSKAVSPPHLDGPPSPRSPVIGSEVFLPNSNHVASGAGEAEERVVVISSSEDSDAENSSSRELDDSSSESSDLQLEGPSTLRVLDENLADPQAEDRPLVFFDLKIDNETQKISQLAAVNRESKFRVVIQPEAFFSIYSKAVSLEVGLQHFLSFLSSMRRPILACYKLWGPGLPNFFRALEDINRLWEFQEAISGFLAALPLIRERVPGASSFKLKNLAQTYLARNMSERSAMAAVLAMRDLCRLLEVSPGPQLAQHVYPFSSLQCFASLQPLVQAAVLPRAEARLLALHNVSFMELLSAHRRDRQGGLKKYSRYLSLQTTTLPPAQPAFNLQALGTYFEGLLEGPALARAEGVSTPLAGRGLAERASQQS", "length": 882 }, "evidence": [ { "id": "FB:FBgn0026206", "url": "https://alliancegenome.org/gene/FB:FBgn0026206#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q503I2-1", "protein_name": "Tripartite motif-containing 13", "gene_name": "trim13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MELLEEDLTCPICCCLFEDPRVLPCSHSFCKKCLEGILDGNRSPTWRPPFKCPTCRKETVHNGIASLQVNYSLRGIVEKYNRIRVMPRMSQCRVHSGQPLNIFCATDLKLICGFCATTGDHKGHKFCALEEAYEREKLAFEELFRVVEGWKGAEVHSCLESLESAKKKALERVSRDADRVSEYFDKLLRTLEHKRSEILSDLETLKLAVMQTFDPEINRLRSALEEQRRALNIAESFRSLSDPLTFLQQMQDFREKLRVIQGTPLPSRTDMDVSLSALQSFDVKEWDRVRLGQVDKLCAPYESSAYLSSLPPAAAPRFTRVMWRVVLVVCACLPALNFLPSDCLALSFQDKVVALGGFSLPSPGEIVRWLGFCWKEAASICTLLTELCRNCMLDLINTTSDFIS", "length": 404 }, "evidence": [ { "id": "FB:FBgn0026206", "url": "https://alliancegenome.org/gene/FB:FBgn0026206#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5ZMD4-1", "protein_name": "Tripartite motif-containing protein 59", "gene_name": "TRIM59", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHQFEEELTCSICYSLFEDPRVLPCSHTFCRSCLEGVIQLSSNFSIWRPLRVPLKCPNCRSIVEIPASGTESLPINFALKAIIEKYRQEDHSDVATCSEHYRQPLNVYCLLDKKLVCGHCLTIGKHNGHPIDDLHSAYLKEKESSGKILEQLTDKHWSDVCLLIEKLKEQKAQCESIVQDDKKVVVQYFKKLSETLEHKKQVLLAALDEINRQILEEYEPHIEKLKKIREEQLELMSLNTSIQKEESPLVFLEKVDNVHQRIKALKEKELPDVKPVEVYPRVGHLLKDVWSKTEIGQINKILTPKIKLVPKRKLHSKNSEKERGKPEELLQAANPLSVTFIFTVIIAIAVLSFHKPISSVVIESIPTHISDFFGFLYQDFCTCMQNTVDVVCHKLNSLAEFLGGIVPF", "length": 408 }, "evidence": [ { "id": "A0A8M9PIB6", "url": "https://omabrowser.org/oma/group/A0A8M9PIB6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q60953-1", "protein_name": "Protein PML", "gene_name": "Pml", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METEPVSVQKVPAPPGSPCRQQDSALTPTPTMPPPEEPSEDYEHSQSPAEQAIQEEFQFLRCPSCQAQAKCPKLLPCLHTLCSGCLEAPGLQCPICKAPGQADANGEALDNVFFESLQRRLAVFRQIVDAQAACTRCKGLADFWCFECEQLICSKCFEAHQWYLKHEARPLADLRDNSVSSFLDSTRKSNIFCSNTNHRNPALTDIYCRGCAKPLCCTCALLDRNHSHLHCDIGEEIQQWHEELGTMTQTLEEQGRTFDSAHAQMCSAIGQLDHARADIEKQIRARVRQVVDYVQAQERELLEAVNDRYQRDYQEIAGQLSCLEAVLQRIRTSGALVKRMKLYASDQEVLDMHSFLRKALCSLRQEEPQNQKVQLLTRGFEEFKLCLQDFISCITQRINAAVASPEAASNQPEAASTHPVTTSTPEDLEQPKEVQSVQAQALELSKTQPVAMVKTVPGAHPVPVYAFSMQGPTYREEASQTVGSMKRKCSHEDCSRKIIKMESTEENEDRLATSSPEQSWPSTFKATSPPHLDGTSNPESTVPEKKILLPNNNHVTSDTGETEERVVVISSSEDSDTENLSSHELDDSSSESSSLQLEGPNSLKALDESLAEPHLEDRTLVFFDLKIDNETQKISQLAAVNRESKFRVLIQPEAFSVYSKAVSLEAGLRHFLSFLTTMHRPILACSRLWGPGLPIFFQTLSDINKLWEFQDTISGFLAVLPLIRERIPGASSFKLGNLAKTYLARNMSERSALASVLAMRDLCCLLEISPGLPLAQHIYSFSSLQCFASLQPLIQASVLPQSEARLLALHNVSFVELLNAYRTNRQEGLKKYVHYLSLQTTPLSSSASTQVAQFLQALSTHMEGLLEGHAPAGAEGKAESKGCLA", "length": 885 }, "evidence": [ { "id": "FB:FBgn0026206", "url": "https://alliancegenome.org/gene/FB:FBgn0026206#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VI1-1", "protein_name": "E3 ubiquitin-protein ligase TRIM56", "gene_name": "Trim56", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSKVSSPTLLEALSSDFLACKICLEQLHTPKTLPCLHTYCQDCLAQLDIGGQVRCPECREIVPVPAEGVAAFKTNFFVNGLLDLVKARAPGDVHSGKPTCALCPLVGGKSSGGPATARCLDCADDLCQACADGHRCSRQTHKHRVVDLVGYRAGWYDEEARERQASQCPQHPGEALCFLCQPCSQLLCKDCRLGPHIDHPCLPLAEAVRSRKPGLEELLAGVDSNLVELEATRVAEKEALALLREQAASVGTQVEEAAERILKSLLAQKQEVLGQLRALVEAAEEATRERLTKIERQEQVAKAAAAFARRVLSLGLEAEILSLEGAITQRLRQLQDAPWTSGPTRCVLPQLELHPGLEDKNCHLLRLIFEEPKQSPKDSGKGGAGTQGGDEAQGQGDDRTKIGKQGGAQPLTPKEGKDQNPQEDDGVFIERGNRPNKKKKCKGRGKSVSREPSPILRPNLEGSGLLPRPVFSWSFPTRMPGDKRSPRITGLCPYGPQEILVADEQNRVLKRFSLNGDYKGTVQVPEGCSPCSVAALQNAVAFSANAKLYLVSPDGEIQWRRSLSLTQSSHAVAAMPCGDRVAVSVAGHVEVYKKDGSLATRFIPGGKASRGQRALVFLTTSPQGNFVGSDWQQNSVVFCDGLGQVIWEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGLEKPRVTTMVDGKYLVVSLSNGTIHVFRVRFPDS", "length": 734 }, "evidence": [ { "id": "FB:FBgn0026206", "url": "https://alliancegenome.org/gene/FB:FBgn0026206#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWR1-1", "protein_name": "Tripartite motif-containing protein 59", "gene_name": "TRIM59", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENILQASGNFYIWRPLRIPLKCPNCRSITEIAPTGIESLPVNFALRAIIEKYQQEDHPDIVTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLEQLTDTHWTDLTHLIEKLKEQKSHSEKMIQGDKEAVLQYFKELNDTLEQKKKSFLTALCDVGNLINQEYTPQIERMKEIREQQLELMALTISLQEESPLKFLEKVDDVRQHVQILKQRPLPEVQPVEIYPRVSKILKEEWSRTEIGQIKNVLIPKMKISPKRMSCSWPGKDEKEVEFLKILNIVVVTLISVILMSILFFNQHIITFLSEITLIWFSEASLSVYQSLSNSLHKVKNILCHIFYLLKEFVWKIVSH", "length": 403 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060724-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060724-2#orthology", "database": "AGR" }, { "id": "HGNC:30834", "url": "https://alliancegenome.org/gene/HGNC:30834#orthology", "database": "AGR" }, { "id": "RGD:1311956", "url": "https://alliancegenome.org/gene/RGD:1311956#orthology", "database": "AGR" }, { "id": "MGI:1914199", "url": "https://alliancegenome.org/gene/MGI:1914199#orthology", "database": "AGR" }, { "id": "A0A8M9PIB6", "url": "https://omabrowser.org/oma/group/A0A8M9PIB6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q922Y2-1", "protein_name": "Tripartite motif-containing protein 59", "gene_name": "Trim59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHNFEEELTCPICYSIFEDPRVLPCSHTFCRNCLENVLQASGNFYIWRPLRIPLKCPNCRSIIEIASTGIESLPVNFALRAIIEKYQQEDHPDVVTCPEHYRQPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLLKQLTDTHWTDITRLIEKLEEQKCHSEKIVQGDKEVVLQYFKELIDTLEQKKKYFLAALCDVGKMINQEYTPQIQGMKEIREQQLELMTITTSLQDESPLKFLEKIDEVRQRVQMLKQRPLPEVQPVEIYPRVSNVLKEEWSRIEIGRIKKAVIPEMRVSSKRTPCSWSDNDEKEMELFKILNIAIVSLISVILMLILLFNHHIITFLNEITSICFSEVFLSVYQSLSKNLYDLNNTVCYTLYLLKEFMWKIVSR", "length": 403 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060724-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060724-2#orthology", "database": "AGR" }, { "id": "HGNC:30834", "url": "https://alliancegenome.org/gene/HGNC:30834#orthology", "database": "AGR" }, { "id": "RGD:1311956", "url": "https://alliancegenome.org/gene/RGD:1311956#orthology", "database": "AGR" }, { "id": "MGI:1914199", "url": "https://alliancegenome.org/gene/MGI:1914199#orthology", "database": "AGR" }, { "id": "A0A8M9PIB6", "url": "https://omabrowser.org/oma/group/A0A8M9PIB6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BRZ2-1", "protein_name": "E3 ubiquitin-protein ligase TRIM56", "gene_name": "TRIM56", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSHGSSPSLLEALSSDFLACKICLEQLRAPKTLPCLHTYCQDCLAQLADGGRVRCPECRETVPVPPEGVASFKTNFFVNGLLDLVKARACGDLRAGKPACALCPLVGGTSTGGPATARCLDCADDLCQACADGHRCTRQTHTHRVVDLVGYRAGWYDEEARERQAAQCPQHPGEALRFLCQPCSQLLCRECRLDPHLDHPCLPLAEAVRARRPGLEGLLAGVDNNLVELEAARRVEKEALARLREQAARVGTQVEEAAEGVLRALLAQKQEVLGQLRAHVEAAEEAARERLAELEGREQVARAAAAFARRVLSLGREAEILSLEGAIAQRLRQLQGCPWAPGPAPCLLPQLELHPGLLDKNCHLLRLSFEEQQPQKDGGKDGAGTQGGEESQSRREDEPKTERQGGVQPQAGDGAQTPKEEKAQTTREEGAQTLEEDRAQTPHEDGGPQPHRGGRPNKKKKFKGRLKSISREPSPALGPNLDGSGLLPRPIFYCSFPTRMPGDKRSPRITGLCPFGPREILVADEQNRALKRFSLNGDYKGTVPVPEGCSPCSVAALQSAVAFSASARLYLINPNGEVQWRRALSLSQASHAVAALPSGDRVAVSVAGHVEVYNMEGSLATRFIPGGKASRGLRALVFLTTSPQGHFVGSDWQQNSVVICDGLGQVVGEYKGPGLHGCQPGSVSVDKKGYIFLTLREVNKVVILDPKGSLLGDFLTAYHGLEKPRVTTMVDGRYLVVSLSNGTIHIFRVRSPDS", "length": 755 }, "evidence": [ { "id": "FB:FBgn0026206", "url": "https://alliancegenome.org/gene/FB:FBgn0026206#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIB6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIB6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PIB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 119, "end_pos": 161, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PIB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIB6" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 37, "end_pos": 87, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 300 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 294, "end_pos": 296 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PD37-1", "uniprot_ac": "A0A8M9PD37", "uniprot_id": "A0A8M9PD37_DANRE", "mass": { "chemical_mass": 98991.0, "monoisotopic_mass": 98991.0 }, "refseq": { "ac": "XP_021322364", "name": "pre-B-cell leukemia homeobox interacting protein 1b isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322364" }, "gene_names": [ { "name": "pbxip1b", "type": "recommended", "evidence": [ { "id": "A0A8M9PD37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37" } ] }, { "name": "im:7138234", "type": "synonym", "evidence": [ { "id": "XP_021322364", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322364" }, { "id": "A0A8M9PD37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37" } ] }, { "name": "pbxip1b", "type": "synonym", "evidence": [ { "id": "XP_021322364", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322364" } ] }, { "name": "wu:fb12b01", "type": "synonym", "evidence": [ { "id": "XP_021322364", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322364" }, { "id": "A0A8M9PD37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37" } ] }, { "name": "zgc:158151", "type": "synonym", "evidence": [ { "id": "XP_021322364", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322364" }, { "id": "A0A8M9PD37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37" } ] } ], "protein_names": [ { "name": "Pre-B-cell leukemia homeobox interacting protein 1b isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PD37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37/entry#names_and_taxonomy" } ] }, { "name": "pre-B-cell leukemia homeobox interacting protein 1b isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322364", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322364" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322364", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322364" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "pbxip1b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070112-2032", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-2032", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PD37", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PD37", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000011824", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000011824", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "553293", "url": "https://www.ncbi.nlm.nih.gov/gene/553293", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:553293", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553293", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HREGKEN", "url": "https://omabrowser.org/oma/group/HREGKEN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z1S6", "url": "https://www.orthodb.org/?gene=A0A8M6Z1S6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PD37", "url": "https://www.orthodb.org/?gene=A0A8M9PD37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F6R0", "url": "https://www.orthodb.org/?gene=E7F6R0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28638", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28638", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28638:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28638:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27631", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27631", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322364", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322364", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1S6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1S6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PD37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PD37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HGG9", "url": "https://www.uniprot.org/uniprotkb/A0AC58HGG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HGG9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HGG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F6R0", "url": "https://www.uniprot.org/uniprotkb/E7F6R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F6R0-1", "url": "https://www.uniprot.org/uniprotkb/E7F6R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070112-2032", "url": "https://zfin.org/ZDB-GENE-070112-2032", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSENGTSTNGNNWTLLTPEVKESGAKNMSPVTEGLKVEEQLSKAPEPSTLAHSDLEKHSSDASAHQPETETSAQIQSDPALSQGSEKTQETQITPPETSEGRAQLNAAHVNEGPSSVSVEDISSWSPDHEEQDALAGHLESPACPGTDAESFSDSYSHISPTTGSSPVPASVCKERDHFKSDEETLRKSTGEEPKEVLETNGKEGDGLRKRKISHLGSLDKTEIEDDEEKEEEDFQPPQREEETVFTLNKCIIAAIILLGLGTIFFSGVLMDADDEADVDVRELKDPPNQDWLNLEDSRDTPVGLQPPDILSKHTKDDQQILALQAQLQQYQGELKAAQLLAETGEKERERREELEKEYQRIKEELDRLPALQKELEQENERMKEESARAQKELKALPSLQSELEHLRAQVSQLTVKAEHQHPIATSRTPPAGDKRDVPPIERPDIRNRKTWDKKTEEKEQSKADKEWKKKKSGKKEGDKDRKEKVTDGEHTKEQKDRKKEEGKAGKQREEKREWKKDKKQDEGKIGRERGEKWGEKREWNDEKKGKKDKHTEKDDKKGNKQDWKDTANKKVKEEKERKQKDWKSDKHSGVNDHREGKENKKEEWKGKKEKGEGKHNEKKWKGDREEHAGKEKEQKHPRGKERESKKEEWTRDHVKEEKKHKAHHPKNELKNSPNEKEKGQKEKHRNTPPDKTSGHHHHEQQNYWTKQRERIQHYDDLRDHCTGVEDCARVEGLSPVHLHDFENLLQSYMNKLQEEQSSSKEELRKLVREFFNNGVFAHDQMPFSEFVEDVGDILEDMAEGEESDTEAEDSEEDDDDDDDDEMEDFEREAMEKFALPAEVKKVEDSSRKKRYMLKLSGLS", "length": 860, "header": "tr|A0A8M9PD37-1|A0A8M9PD37_DANRE Isoform 1 of Pre-B-cell leukemia homeobox interacting protein 1b isoform X1 OS=Danio rerio OX=7955 GN=pbxip1b PE=1 SV=1 CANONICAL=A0A8M9PD37-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1S6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37/entry#A0A8M6Z1S6-1", "sequence": { "sequence": "MSENGTSTNGNNWTLLTPEVKESGAKNMSPVTEGLKVEEQLSKAPEPSTLAHSDLEKHSSDASAHQPETETSAQIQSDPALSQGSEKTQETQITPPETSEGRAQLNAAHVNEGPSSVSVEDISSWSPDHEEQDALAGHLESPACPGTDAESFSDSYSHISPTTGSSPVPASVCKERDHFKSDEETLRKSTGEEPKEVLETNGKEGDGLRKRKISHLGSLDKTEIEDDEEKEEEDFQPPQREEETVFTLNKCIIAAIILLGLGTIFFSGVLMDADDEADVDVRELKDPPNQDWLNLEDSRDTPVGLQPPDILSKHTKDDQQILALQAQLQQYQGELKAAQLLAETGEKERERREELEKEYQRIKEELDRLPALQKELEQENERMKEESARAQKELKALPSLQSELEHLRAQVSQLTVKAEHQHPIATSRTPPAGDKRDVPPIERPDIRNRKTWDKKTEEKEQSKADKEWKKKKSGKKEGDKDRKEKVTDGEHTKEQKDRKKEEGKAGKQREEKREWKKDKKQDEGKIGRERGEKWGEKREWNDEKKGKKDKHTEKDDKKGNKQDWKDTANKKVKEEKERKQKDWKSDKHSGVNDHREGKENKKEEWKGKKEKGEGKHNEKKWKGDREEHAGKEKEQKHPRGKERESKKEEWTRDHVKEEKKHKAHHPKNELKNSPNEKEKGQKEKHRNTPPDKTSGHHHHEQQNYWTKQRERIQHYDDLRDHCTGVEDCARVEGLSPVHLHDFENLLQSYMNKLQEEQSSSKEELRKLVREFFNNGVFAHDQMPFSEFVEDVGDILEDMAEGEESDTEAEDSEEDDDDDDDDEMEDFEREAMEKFALPAEVKKVEDSSRKKR", "length": 851, "header": "tr|A0A8M6Z1S6-1|A0A8M9PD37_DANRE Computationally mapped isoform of Pre-B-cell leukemia homeobox interacting protein 1b isoform X1 OS=Danio rerio OX=7955 GN=pbxip1b PE=1 SV=1 CANONICAL=A0A8M9PD37-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PD37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37/entry#A0A8M9PD37-1", "sequence": { "sequence": "MSENGTSTNGNNWTLLTPEVKESGAKNMSPVTEGLKVEEQLSKAPEPSTLAHSDLEKHSSDASAHQPETETSAQIQSDPALSQGSEKTQETQITPPETSEGRAQLNAAHVNEGPSSVSVEDISSWSPDHEEQDALAGHLESPACPGTDAESFSDSYSHISPTTGSSPVPASVCKERDHFKSDEETLRKSTGEEPKEVLETNGKEGDGLRKRKISHLGSLDKTEIEDDEEKEEEDFQPPQREEETVFTLNKCIIAAIILLGLGTIFFSGVLMDADDEADVDVRELKDPPNQDWLNLEDSRDTPVGLQPPDILSKHTKDDQQILALQAQLQQYQGELKAAQLLAETGEKERERREELEKEYQRIKEELDRLPALQKELEQENERMKEESARAQKELKALPSLQSELEHLRAQVSQLTVKAEHQHPIATSRTPPAGDKRDVPPIERPDIRNRKTWDKKTEEKEQSKADKEWKKKKSGKKEGDKDRKEKVTDGEHTKEQKDRKKEEGKAGKQREEKREWKKDKKQDEGKIGRERGEKWGEKREWNDEKKGKKDKHTEKDDKKGNKQDWKDTANKKVKEEKERKQKDWKSDKHSGVNDHREGKENKKEEWKGKKEKGEGKHNEKKWKGDREEHAGKEKEQKHPRGKERESKKEEWTRDHVKEEKKHKAHHPKNELKNSPNEKEKGQKEKHRNTPPDKTSGHHHHEQQNYWTKQRERIQHYDDLRDHCTGVEDCARVEGLSPVHLHDFENLLQSYMNKLQEEQSSSKEELRKLVREFFNNGVFAHDQMPFSEFVEDVGDILEDMAEGEESDTEAEDSEEDDDDDDDDEMEDFEREAMEKFALPAEVKKVEDSSRKKRYMLKLSGLS", "length": 860, "header": "tr|A0A8M9PD37-1|A0A8M9PD37_DANRE Isoform 1 of Pre-B-cell leukemia homeobox interacting protein 1b isoform X1 OS=Danio rerio OX=7955 GN=pbxip1b PE=1 SV=1 CANONICAL=A0A8M9PD37-1" }, "locus": {} }, { "isoform_ac": "A0AC58HGG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37/entry#A0AC58HGG9-1", "sequence": { "sequence": "MSENGTSTNGNNWTLLTPEVKESGAKNMSPVTEGLKVEEQLSKAPEPSTLAHSDLEKHSSDASAHQPETETSAQIQSDPALSQGSEKTQETQITPPETSEGRAQLNAAHVNEGPSSVSVEDISSWSPDHEEQDALAGHLESPACPGTDAESFSDSYSHISPTTGSSPVPASVCKERDHFKSDEETLRKSTGEEPKEVLETNGKEGDGLRKRKISHLGSLDKTEIEDDEEKEEEDFQPPQREEETVFTLNKCIIAAIILLGLGTIFFSEADVDVRELKDPPNQDWLNLEDSRDTPVGLQPPDILSKHTKDDQQILALQAQLQQYQGELKAAQLLAETGEKERERREELEKEYQRIKEELDRLPALQKELEQENERMKEESARAQKELKALPSLQSELEHLRAQVSQLTVKAEHQHPIATSRTPPAGDKRDVPPIERPDIRNRKTWDKKTEEKEQSKADKEWKKKKSGKKEGDKDRKEKVTDGEHTKEQKDRKKEEGKAGKQREEKREWKKDKKQDEGKIGRERGEKWGEKREWNDEKKGKKDKHTEKDDKKGNKQDWKDTANKKVKEEKERKQKDWKSDKHSGVNDHREGKENKKEEWKGKKEKGEGKHNEKKWKGDREEHAGKEKEQKHPRGKERESKKEEWTRDHVKEEKKHKAHHPKNELKNSPNEKEKGQKEKHRNTPPDKTSGHHHHEQQNYWTKQRERIQHYDDLRDHCTGVEDCARVEGLSPVHLHDFENLLQSYMNKLQEEQSSSKEELRKLVREFFNNGVFAHDQMPFSEFVEDVGDILEDMAEGEESDTEAEDSEEDDDDDDDDEMEDFEREAMEKFALPAEVKKVEDSSRKKR", "length": 843, "header": "tr|A0AC58HGG9-1|A0AC58HGG9_DANRE Computationally mapped isoform of Pre-B-cell leukemia homeobox interacting protein 1b isoform X4 OS=Danio rerio OX=7955 GN=pbxip1b PE=1 SV=1 CANONICAL=A0A8M9PD37-1" }, "locus": {} }, { "isoform_ac": "E7F6R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37/entry#E7F6R0-1", "sequence": { "sequence": "MSENGTSTNGNNWTLLTPEVKESGAKNMSPVTEGLKVEEQLSKAPEPSTLAHSDLEKHSSDASAHQPETETSAQIQSDPALSQGSEKTQETQITPPETSEGRAQLNAAHVNEGPSSVSVEDISSWSPDHEEQDALAGHLESPACPGTDAESFSDSYSHISPTTGSSPVPASVCKERDHFKSDEETLRKSTGEEPKEVLETNGKEGDGLRKRKISHLGSLDKTEIEDDEEKEEEDFQPPQREEETVFTLNKCIIAAIILLGLGTIFFSEADVDVRELKDPPNQDWLNLEDSRDTPVGLQPPDILSKHTKDDQQILALQAQLQQYQGELKAAQLLAETGEKERERREELEKEYQRIKEELDRLPALQKELEQENERMKEESARAQKELKALPSLQSELEHLRAQVSQLTVKAEHQHPIATSRTPPAGDKRDVPPIERPDIRNRKTWDKKTEEKEQSKADKEWKKKKSGKKEGDKDRKEKVTDGEHTKEQKDRKKEEGKAGKQREEKREWKKDKKQDEGKIGRERGEKWGEKREWNDEKKGKKDKHTEKDDKKGNKQDWKDTANKKVKEEKERKQKDWKSDKHSGVNDHREGKENKKEEWKGKKEKGEGKHNEKKWKGDREEHAGKEKEQKHPRGKERESKKEEWTRDHVKEEKKHKAHHPKNELKNSPNEKEKGQKEKHRNTPPDKTSGHHHHEQQNYWTKQRERIQHYDDLRDHCTGVEDCARVEGLSPVHLHDFENLLQSYMNKLQEEQSSSKEELRKLVREFFNNGVFAHDQMPFSEFVEDVGDILEDMAEGEESDTEAEDSEEDDDDDDDDEMEDFEREAMEKFALPAEVKKVEDSSRKKRYMLKLSGLS", "length": 852, "header": "tr|E7F6R0-1|A0A8M9PD37_DANRE Computationally mapped isoform of Pre-B-cell leukemia homeobox interacting protein 1b isoform X1 OS=Danio rerio OX=7955 GN=pbxip1b PE=1 SV=2 CANONICAL=A0A8M9PD37-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 162, "start_aa": "Thr", "end_pos": 162, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr162", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain.", "journal": "PLoS ONE", "date": "2008", "authors": "Sreenivasan Rajini, Cai Minnie, Bartfai Richard, Wang Xingang, Christoffels Alan, Orban Laszlo", "evidence": [ { "database": "UniProtKB", "id": "E7F6R0", "url": "https://www.uniprot.org/uniprotkb/E7F6R0" } ], "reference": [ { "type": "PubMed", "id": "18335061", "url": "https://glygen.org/publication/PubMed/18335061" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7F6R0", "url": "https://www.uniprot.org/uniprotkb/E7F6R0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene expression profiling of granule cells and Purkinje cells in the zebrafish cerebellum.", "journal": "J. Comp. Neurol.", "date": "2017", "authors": "Takeuchi Miki, Yamaguchi Shingo, Sakakibara Yoshimasa, Hayashi Takuto, Matsuda Koji, Hara Yuichiro, Tanegashima Chiharu, Shimizu Takashi, Kuraku Shigehiro, Hibi Masahiko", "evidence": [ { "database": "UniProtKB", "id": "E7F6R0", "url": "https://www.uniprot.org/uniprotkb/E7F6R0" } ], "reference": [ { "type": "PubMed", "id": "27615194", "url": "https://glygen.org/publication/PubMed/27615194" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "E7F6R0", "url": "https://www.uniprot.org/uniprotkb/E7F6R0" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] } ], "pathway": [ { "id": "dre:553293", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553293", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B630-1", "protein_name": "Uncharacterized protein pbxip1a isoform X1", "gene_name": "pbxip1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDNSTGSTGSSTNSWTLLSPEEVAADPTAPVDDGTESIGDAPSLSEDIAGSSLEVRSHDPETPILEPVLSEEGQQVSAPPPICQETSPDFLEEMAASGPPEVELDPDIHAPIIHDTITSSPPDSDLLGAVPFSIATESAFQFSEESVLDEPTEEDVTDIFPSQHVPIQESPAPQPEPKITSTPEPFREVSSALDVSEVSAEISHAHTIRGDSALPVLDIHADVHPAPETPPLASPSEDDTGFGTTLESPAPDSPYPETIGSIETEEERSFEKENIELPEKLPDVIREPESLGAEFPAVSSAGDDDGLRFRHVQPTIVLKRSSDEEEEEGEEEEFNLPVRKEEKRGFSLNQLIVGALVLLCVGSFFFSGSVFDLADDDFDGTELSDQELLDKLAQENKQINILEAQIESQKEELDQALKMASQVHSTEKGALENENTKLKEQLSELPGLKEELQMLRARVAELTKLTAEDLTQTIPDSDPPSTADSVPEEAEKHRDKKEELKRQKALLEESRKRLEGMKKPSWNKQGLRESLVEMQKRLSKQVEQLGKREDWKRKHKKEWGRKKEHDWKKDEAEKGKEWKHGKDKRKEHLMKYKEEWDLNKDERRQERERRQKERPWDAKSSKHQHHHEKANFWRHQEEKLRRNRHPAEGCRGVSNCADAEGLVPVRLPEFQDLLDVYTSKLEAVPQENKESLKRLTAQFFSGGIFAHDRMLFSEFAEDVADILEDLADEQHDNESLEEEMEEFEKEALLKFAATSA", "length": 757 }, "evidence": [ { "id": "HGNC:21199", "url": "https://alliancegenome.org/gene/HGNC:21199#orthology", "database": "AGR" }, { "id": "MGI:2441670", "url": "https://alliancegenome.org/gene/MGI:2441670#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2VD12-1", "protein_name": "Pre-B-cell leukemia transcription factor-interacting protein 1", "gene_name": "Pbxip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASCPDSDNSWVLAGSETLPVETLGPESRVDPESEEAPQALQDSSKADGKESAGTLNGEEMLFQTESSQGEGAALPEESEAKGALGGDDGHGTKRPGDTAVQEDLQETPMVTSLGPDTQDLERNIHPQNLPSSPRAVWKEHGCSSSDDDTDVDVEGLRRRRGREPSPPQPTAAVDGEDQAKGEGIGELGISLNMCFLGALVLLGLGILLFSGALLEPETEPVEEAELQVFPETELVQTVGNRQDEVEQLQASVPPDSVPSLQSMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLLHQPKGLEEENARLREALQQGKTSHQALESELQQLRARLQGLEANCVRGVDGVCLNWGGSPQGGKATTEQGHKGQEPDTSLLEQHKQLEAEAKALRQELQKQWQLLGSVHRNLQRGLQDAGQGAPAHAGLAELGHMLAQTLQGLESQGINTGRSSNDSEAWHQKKPRFQHPREWSGREKWRGGQRDQKAEHWKLKKEESGQDRKKSWRDEGREFTGHWKENRPRAEESGSRKDSKRQDPKVHPRKSGNSHSGERQKHSWGKDNSPDSVSWEELLRRKYRPPQGCSGVADCARQEGLALFGVELAPVRQQELASVLREYLARLPWAGQLTKELPLSPAYFGEDGIFRHDRLRFRDFVDALEDSLEEVALKQTGDDDEVDDFEDFIFSHFFGDKALKRRSKKKEKQPWNHRAVGPREEHSRHPHHYHQG", "length": 722 }, "evidence": [ { "id": "HGNC:21199", "url": "https://alliancegenome.org/gene/HGNC:21199#orthology", "database": "AGR" }, { "id": "MGI:2441670", "url": "https://alliancegenome.org/gene/MGI:2441670#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3TVI8-1", "protein_name": "Pre-B-cell leukemia transcription factor-interacting protein 1", "gene_name": "Pbxip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASCPDSDNSWVLAGSENLPVETLGPEPRMDPESEGASQALRDSSKADGKELAGTLDGEEKLFQTESSQRETAVLTESAAKGTLGADGHGTEAPGDTVVQEDSQETPVATSLGPDTQDLESEIHPQNLPSSPRAVWKEHRCSSSDDDTDVDVEGLRRRRGREPSSSQPVVPVDVEDQAKGEGIGGELGISLNMCFLGALVLLGLGILLFSGTLLEPETGPMEEAELQVFPETGPETELVETLGNRQDEIEHLQASSVPPDSVPSLQSMGFLLDKLAKENQDIRLLQAQLQAQKEELQSLLHQPKGLEEENARLREALQQGKTSHQALESELQQLRARLQGLEANCVRGVDGVCLNWGGDPQDGKATKEQGHKGQEPDPSLLEQHKQLEAEAKALRQELQRQWQLLGSVHWDLQRGLRDAGRGAPAHPGLAELGHMLAQTLQDLENQGINTGRSPNDSEAWHQKKPHTQSPREWGGKEKWRGGQRDQKAEHWKPRKEESGQERQRSWRDEGREHTGRWREDRLRADESGSRKDSKRQDPKVHPRKDGNSHSVERQKHSWGKDNSPDALSSWEELLRRKYRPPQGCSGVADCARQEGLALFGVELAPVRQQELASVLREYLSRLPWAGQLTKQLPLSPAYFGEDGIFRHDRLRFRDFVDALEDSLEEVALKQTGDDDEVDDFEDFVFGHFFGDKALKKRSRKKEKHSWNPRVVGPREEHSRHPHHYHQG", "length": 727 }, "evidence": [ { "id": "HGNC:21199", "url": "https://alliancegenome.org/gene/HGNC:21199#orthology", "database": "AGR" }, { "id": "MGI:2441670", "url": "https://alliancegenome.org/gene/MGI:2441670#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-2032", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-2032#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AQ6-1", "protein_name": "Pre-B-cell leukemia transcription factor-interacting protein 1", "gene_name": "PBXIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASCPDSDNSWVLAGSESLPVETLGPASRMDPESERALQAPHSPSKTDGKELAGTMDGEGTLFQTESPQSGSILTEETEVKGTLEGDVCGVEPPGPGDTVVQGDLQETTVVTGLGPDTQDLEGQSPPQSLPSTPKAAWIREEGRCSSSDDDTDVDMEGLRRRRGREAGPPQPMVPLAVENQAGGEGAGGELGISLNMCLLGALVLLGLGVLLFSGGLSESETGPMEEVERQVLPDPEVLEAVGDRQDGLREQLQAPVPPDSVPSLQNMGLLLDKLAKENQDIRLLQAQLQAQKEELQSLMHQPKGLEEENAQLRGALQQGEAFQRALESELQQLRARLQGLEADCVRGPDGVCLSGGRGPQGDKAIREQGPREQEPELSFLKQKEQLEAEAQALRQELERQRRLLGSVQQDLERSLQDASRGDPAHAGLAELGHRLAQKLQGLENWGQDPGVSANASKAWHQKSHFQNSREWSGKEKWWDGQRDRKAEHWKHKKEESGRERKKNWGGQEDREPAGRWKEGRPRVEESGSKKEGKRQGPKEPPRKSGSFHSSGEKQKQPRWREGTKDSHDPLPSWAELLRPKYRAPQGCSGVDECARQEGLTFFGTELAPVRQQELASLLRTYLARLPWAGQLTKELPLSPAFFGEDGIFRHDRLRFRDFVDALEDSLEEVAVQQTGDDDEVDDFEDFIFSHFFGDKALKKRSGKKDKHSQSPRAAGPREGHSHSHHHHHRG", "length": 731 }, "evidence": [ { "id": "HGNC:21199", "url": "https://alliancegenome.org/gene/HGNC:21199#orthology", "database": "AGR" }, { "id": "MGI:2441670", "url": "https://alliancegenome.org/gene/MGI:2441670#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-2032", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-2032#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 162 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 12, "end_pos": 14 }, { "start_pos": 27, "end_pos": 29 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M6Z8X0-1", "uniprot_ac": "A0A8M6Z8X0", "uniprot_id": "A0A8M6Z8X0_DANRE", "mass": { "chemical_mass": 230676.0, "monoisotopic_mass": 230676.0 }, "refseq": { "ac": "XP_017213569", "name": "remodeling and spacing factor 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213569" }, "gene_names": [ { "name": "rsf1b.1", "type": "recommended", "evidence": [ { "id": "A0A8M6Z8X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0" } ] }, { "name": "rsf1b.1", "type": "synonym", "evidence": [ { "id": "XP_017213569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213569" } ] } ], "protein_names": [ { "name": "Remodeling and spacing factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z8X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0/entry#names_and_taxonomy" } ] }, { "name": "remodeling and spacing factor 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017213569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213569" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017213569.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213569" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rsf1b.1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-5829", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5829", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd15543", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15543", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "327618", "url": "https://www.ncbi.nlm.nih.gov/gene/327618", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018501", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018501", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028942", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028942", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:327618", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:327618", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z1G1", "url": "https://www.orthodb.org/?gene=A0A8M6Z1G1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z8X0", "url": "https://www.orthodb.org/?gene=A0A8M6Z8X0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14296", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14296", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14296:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14296:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213569", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1G1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z1G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z1G1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8X0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-5829", "url": "https://zfin.org/ZDB-GENE-030131-5829", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLVWVSSRCFGFLFSPNQPDLTKKNTWRKPTPTRGEHANSSTGPAGTQTSDLPAVSSIPSARACGPCVCHSRGALWEGCGPPAARFGIMSASEEADGSSPGLCPSFAVICSFLERYGALLDLPEVSFPELERSLQDSSAVPKLLVDLHVKLLRKIGKSVSAERWEKYLIKICQEFNTTWAWELEKKGYQELTVECKTGILKYLCECQFDDNVKFKNAINEEDPDKMRLQPIGRDKDGLMYWFQLDQDHNVRIYVEEQDDLDGSSWKCIVRNRDDLAQILGLLKTQIDPALLVKKEQEEGSSNNSPNPDDEENKKKEGAEVEKSQDDLSKSENKENILEKENKKEEDADATDALSEKGLKVKEELQKHSEKANGSDVIAGSIKEEPQDDEKVFSAPSKKAEQTEEVKRKTLEETQRALKNDHQAKIPLKKREMKLSEDFDSNSAGLRSAPVKESRTCFDDSRSSAEKINGHVPHLQKEATDSESLSHFESNEKTKDAQVDRKMDTNETRFPSEEKMEVEKPKEKNEASTKQHKTTPGEEKPSELSEKTPDSEVVTENMETIEDIKTTPCDDTANELPKEKSIKDIPNKESKEDSLKDAQSKESKEESLKGSKESKGESSLKDAPSKESKEESLKDAPSKESKESSSKDAPSKESKGELLKESKESKKESLKDTPSKESIGESLKDTQIKESKESSSKDAPRKESKEESLKDAPSKESKEDSMKDTPSKESNESLLKESKESKEESLKDNPSKESKEEILKDTPSKESKQKSLKDTPSKESKQESLKDTPSKESKGESLKDAPSKESKESLLKESKESKEESLKDPPGKESAKSKDDKTKALSKKESLQDISNEKSAKSLKDDATKDPSKKESLQDISNESTKSVSKDEAAQDHFNKESSKDLASEESGKDQPAKDLSNEESIKNPPNQKPSKDLAKKESQKVIPESESQKVVSEKELQKGIPEKGSQKSNPEKKSQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNTEKESQKSNTEKESQNVLPSQKSPNKDQEQAMETESFHSLKSVETREIIKPHSDTEKPENAEKTKLHESNTEKESTQKPCISEGDKLLTRGESIGSKPCEDTDNPQDKKQEKSGSSKSRTDTNKSSVSDSKKSETRKKVDAENKCDAAETAKSDKSEIAEDKDKKSESTKTSDEVKAPEKPNKSDKEHEKQPNPMETDSEIPKTAEETTKESVKEANAPVDNSTSKQSERDATSEEREASGVVQEKGKGIKKPGRPSKKSTESQNKDKTVEEEKDDGKRRGRTPLKLKKPAHRRKAEIQREELKGDSESETTDGRCLRRSPRICRPTAKAVEIQDKRAERKQATPEKEKEEEEEEEEEEPVQRKLRKAEPDGQTKPKVGRRRKRQPWSRMRRKKKSSEDEEDEEESESEEEETEEDDSDEDYKVEKSKKRRRNRNRERRSSDSSTSSSEDDTPNDDPCKHCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCDRLEEQLLNLDAALKKKERAERRKERLVYVGISVENIITPSVEVEEEKEEVLVKDKAETKKSKGWGRRSTRAKKYISYRFDEFDEAIEEAIEEDIKEAEGGGAGRGKDMANITGHRGKDMSTILQEEGKENGRPQRTSAAQKKKRRRLNDLDSDSTVDEEESEDEFRLSDSSSEEEFVASENAESEDNAPSLEDSDFDSDAQGSRVNRANRRKTSRSRIRRKQPPRRRRRPRGYSDEEELETDEEEEEEDEMVTEGSSEFSDSDLDVRCRRSYRSRKQEVNYCETSDSDGSQASTNKDKKKKRRRLSSSDSEASFQSAESEEEERKPKKIRADSSEEESRKRRRRLSLKRRRESEDDDDDDDSDESEEEERPVRKRVNRIDSDESESEEEEKEVKKSPQEKDTEETSANKGPSPINDNTAEPPSTNGQSPIKGLEGVAPRPGAGATPKNGNTPSIAPNGLEAGAQEEDEDDLLGVTDLVDYVCNSEQL", "length": 2046, "header": "tr|A0A8M6Z8X0-1|A0A8M6Z8X0_DANRE Isoform 1 of Remodeling and spacing factor 1 isoform X1 OS=Danio rerio OX=7955 GN=rsf1b.1 PE=1 SV=2 CANONICAL=A0A8M6Z8X0-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z1G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0/entry#A0A8M6Z1G1-1", "sequence": { "sequence": "MSASEEADGSSPGLCPSFAVICSFLERYGALLDLPEVSFPELERSLQDSSAVPKLLVDLHVKLLRKIGKSVSAERWEKYLIKICQEFNTTWAWELEKKGYQELTVECKTGILKYLCECQFDDNVKFKNAINEEDPDKMRLQPIGRDKDGLMYWFQLDQDHNVRIYVEEQDDLDGSSWKCIVRNRDDLAQILGLLKTQIDPALLVKKEQEEGSSNNSPNPDDEENKKKEGAEVEKSQDDLSKSENKENILEKENKKEEDADATDALSEKGLKVKEELQKHSEKANGSDVIAGSIKEEPQDDEKVFSAPSKKAEQTEEVKRKTLEETQRALKNDHQAKIPLKKREMKLSEDFDSNSAGLRSAPVKESRTCFDDSRSSAEKINGHVPHLQKEATDSESLSHFESNEKTKDAQVDRKMDTNETRFPSEEKMEVEKPKEKNEASTKQHKTTPGEEKPSELSEKTPDSEVVTENMETIEDIKTTPCDDTANELPKEKSIKDIPNKESKEDSLKDAQSKESKEESLKGSKESKGESSLKDAPSKESKEESLKDAPSKESKESSSKDAPSKESKGELLKESKESKKESLKDTPSKESIGESLKDTQIKESKESSSKDAPRKESKEESLKDAPSKESKEDSMKDTPSKESNESLLKESKESKEESLKDNPSKESKEEILKDTPSKESKQKSLKDTPSKESKQESLKDTPSKESKGESLKDAPSKESKESLLKESKESKEESLKDPPGKESAKSKDDKTKALSKKESLQDISNEKSAKSLKDDATKDPSKKESLQDISNESTKSVSKDEAAQDHFNKESSKDLASEESGKDQPAKDLSNEESIKNPPNQKPSKDLAKKESQKVIPESESQKVVSEKELQKGIPEKGSQKSNPEKKSQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNTEKESQKSNTEKESQNVLPSQKSPNKDQEQAMETESFHSLKSVETREIIKPHSDTEKPENAEKTKLHESNTEKESTQKPCISEGDKLLTRGESIGSKPCEDTDNPQDKKQEKSGSSKSRTDTNKSSVSDSKKSETRKKVDAENKCDAAETAKSDKSEIAEDKDKKSESTKTSDEVKAPEKPNKSDKEHEKQPNPMETDSEIPKTAEETTKESVKEANAPVDNSTSKQSERDATSEEREASGVVQEKGKGIKKPGRPSKKSTESQNKDKTVEEEKDDGKRRGRTPLKLKKPAHRRKAEIQREELKGDSESETTDGRCLRRSPRICRPTAKAVEIQDKRAERKQATPEKEKEEEEEEEEEEPVQRKLRKAEPDGQTKPKQVGRRRKRQPWSRMRRKKKSSEDEEDEEESESEEEETEEDDSDEDYKVEKSKKRRRNRNRERRSSDSSTSSSEDDTPNDDPCKHCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCDRLEEQLLNLDAALKKKERAERRKERLVYVGISVENIITPSVEVEEEKEEVLVKDKAETKKSKGWGRRSTRAKKYISYRFDEFDEAIEEAIEEDIKEAEGGGAGRGKDMANITGHRGKDMSTILQEEGKENGRPQRTSAAQKKKRRRLNDLDSDSTVDEEESEDEFRLSDSSSEEEFVASENAESEDNAPSLEDSDFDSDAQGSRVNRANRRKTSRSRIRRKQPPRRRRRPRGYSDEEELETDEEEEEEDEMVTEGSSEFSDSDLDVRCRRSYRSRKQEVNYCETSDSDGSQASTNKDKKKKRRRLSSSDSEASFQSAESEEEERKPKKIRADSSEEESRKRRRRLSLKRRRESEDDDDDDDSDESEEEERPVRKRVNRIDSDESESEEEEKEVKKSPQEKDTEETSANKGPSPINDNTAEPPSTNGQSPIKGLEGVAPRPGAGATPKNGNTPSIAPNGLEAGAQEEDEDDLLGVTDLVDYVCNSEQL", "length": 1959, "header": "tr|A0A8M6Z1G1-1|A0A8M6Z8X0_DANRE Computationally mapped isoform of Remodeling and spacing factor 1 isoform X1 OS=Danio rerio OX=7955 GN=rsf1b.1 PE=1 SV=2 CANONICAL=A0A8M6Z8X0-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z8X0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0/entry#A0A8M6Z8X0-1", "sequence": { "sequence": "MLVWVSSRCFGFLFSPNQPDLTKKNTWRKPTPTRGEHANSSTGPAGTQTSDLPAVSSIPSARACGPCVCHSRGALWEGCGPPAARFGIMSASEEADGSSPGLCPSFAVICSFLERYGALLDLPEVSFPELERSLQDSSAVPKLLVDLHVKLLRKIGKSVSAERWEKYLIKICQEFNTTWAWELEKKGYQELTVECKTGILKYLCECQFDDNVKFKNAINEEDPDKMRLQPIGRDKDGLMYWFQLDQDHNVRIYVEEQDDLDGSSWKCIVRNRDDLAQILGLLKTQIDPALLVKKEQEEGSSNNSPNPDDEENKKKEGAEVEKSQDDLSKSENKENILEKENKKEEDADATDALSEKGLKVKEELQKHSEKANGSDVIAGSIKEEPQDDEKVFSAPSKKAEQTEEVKRKTLEETQRALKNDHQAKIPLKKREMKLSEDFDSNSAGLRSAPVKESRTCFDDSRSSAEKINGHVPHLQKEATDSESLSHFESNEKTKDAQVDRKMDTNETRFPSEEKMEVEKPKEKNEASTKQHKTTPGEEKPSELSEKTPDSEVVTENMETIEDIKTTPCDDTANELPKEKSIKDIPNKESKEDSLKDAQSKESKEESLKGSKESKGESSLKDAPSKESKEESLKDAPSKESKESSSKDAPSKESKGELLKESKESKKESLKDTPSKESIGESLKDTQIKESKESSSKDAPRKESKEESLKDAPSKESKEDSMKDTPSKESNESLLKESKESKEESLKDNPSKESKEEILKDTPSKESKQKSLKDTPSKESKQESLKDTPSKESKGESLKDAPSKESKESLLKESKESKEESLKDPPGKESAKSKDDKTKALSKKESLQDISNEKSAKSLKDDATKDPSKKESLQDISNESTKSVSKDEAAQDHFNKESSKDLASEESGKDQPAKDLSNEESIKNPPNQKPSKDLAKKESQKVIPESESQKVVSEKELQKGIPEKGSQKSNPEKKSQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNPEKESQKSNTEKESQKSNTEKESQNVLPSQKSPNKDQEQAMETESFHSLKSVETREIIKPHSDTEKPENAEKTKLHESNTEKESTQKPCISEGDKLLTRGESIGSKPCEDTDNPQDKKQEKSGSSKSRTDTNKSSVSDSKKSETRKKVDAENKCDAAETAKSDKSEIAEDKDKKSESTKTSDEVKAPEKPNKSDKEHEKQPNPMETDSEIPKTAEETTKESVKEANAPVDNSTSKQSERDATSEEREASGVVQEKGKGIKKPGRPSKKSTESQNKDKTVEEEKDDGKRRGRTPLKLKKPAHRRKAEIQREELKGDSESETTDGRCLRRSPRICRPTAKAVEIQDKRAERKQATPEKEKEEEEEEEEEEPVQRKLRKAEPDGQTKPKVGRRRKRQPWSRMRRKKKSSEDEEDEEESESEEEETEEDDSDEDYKVEKSKKRRRNRNRERRSSDSSTSSSEDDTPNDDPCKHCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCDRLEEQLLNLDAALKKKERAERRKERLVYVGISVENIITPSVEVEEEKEEVLVKDKAETKKSKGWGRRSTRAKKYISYRFDEFDEAIEEAIEEDIKEAEGGGAGRGKDMANITGHRGKDMSTILQEEGKENGRPQRTSAAQKKKRRRLNDLDSDSTVDEEESEDEFRLSDSSSEEEFVASENAESEDNAPSLEDSDFDSDAQGSRVNRANRRKTSRSRIRRKQPPRRRRRPRGYSDEEELETDEEEEEEDEMVTEGSSEFSDSDLDVRCRRSYRSRKQEVNYCETSDSDGSQASTNKDKKKKRRRLSSSDSEASFQSAESEEEERKPKKIRADSSEEESRKRRRRLSLKRRRESEDDDDDDDSDESEEEERPVRKRVNRIDSDESESEEEEKEVKKSPQEKDTEETSANKGPSPINDNTAEPPSTNGQSPIKGLEGVAPRPGAGATPKNGNTPSIAPNGLEAGAQEEDEDDLLGVTDLVDYVCNSEQL", "length": 2046, "header": "tr|A0A8M6Z8X0-1|A0A8M6Z8X0_DANRE Isoform 1 of Remodeling and spacing factor 1 isoform X1 OS=Danio rerio OX=7955 GN=rsf1b.1 PE=1 SV=2 CANONICAL=A0A8M6Z8X0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:327618", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:327618", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1QHL2-1", "protein_name": "Remodeling and spacing factor 1", "gene_name": "rsf1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAPGTTSTAALAPAHSPGFAVVCSFLERYGPVLDLPELSFPQLERYLQDTSAVPRPLIELHIKLLRKIGKSVTPDRWEKYLVKVCQEFNSTWAWEMERKSYLEMTVECKTDILKYLCECQFDDNLKFKTLINEEDPDTMRLQPIGRDKEGLLYWFQLDQEQNIRVYSEEQDDLDGSSWKLIARNRNDLADTLEQLKAKIEPAVTDQDKQDAPTSPNMETEGVKGEVGDLKNHIPGQVDFTNSTIRSNKIDSISKEIKKETPMDLVKSEKLTQNLNPRVVIDNRVSTIKTLVKQEPKDCPKPWNAISVVMPPASIKQEPAIKPETNEDKKETLFENLARTIKSDQQAKIPLKKRELKRSGGYDVTNHYSNINHNNNNLNSNGSISTGGIIVRNPAVLPLKEEQIKGQYPGDGDKGSMGIITVPQEPIGKLDINQYIGVGVIKGPIERKRPLDENDSSSNGHHGNGNVLTEVAGTDSVRQSVLVGNTMVKEDGPLTCSIPEDLSKDGCNKMLDVSAKVVEESTTEMQTTSVEETIEKSDNKELKNTKTIGEEADVVVQDEGKSKGPKGTRKRRSQKTKSKLQVREDSQKMKLSSNIGEVLKRKTGEGEKNGRNNDEEVSSELQKEGIRLKIKIPLHRRTPELQHKEIEESETGNRRSLRRSARISKPSPKVANSRDGKQDRKLSAAQYEDEHVDNEKAKVLSKKVDTPKPLKGKRRHRRTRWSRIRMKNCKSKVAQEEEAVDDKAENDDNKSEKGDHNSEAESEQSNEFPPEDACKHCGLANHPELILLCDLCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCERLEEQLQNLDTALKKKERAERRRERLVYVGISVENIIPGPDGDGEDSLMEKKKDPKKSKNLGRRSTRTRKSISYRFDDFDEAIDEAIEEDLQDSEGGAAGGGKPLANVVSQQKSAVNRESRRPVKPVAPRKKKRRRLNDLDSDSTVDEEESEDEFQLSESMEEDFVVSGDGASDGDVGSYEGSEWGSGESEAENKPASRRTGKPAQTRRSRRSKRRPAARRRGSSEEDLLDSEEEEEEEDMETEGSDCSDTEVDVNRRRPRRSHNSQVNYYETSESEGSQKPSDLKHSSHAHRRRLSSSNSEESALSKDFKPKVLLQRSDRVQKKCTPAGEDSKHRHKLIKQRPQRSSSEDEEEDGGETEESEEEERPMRKRSNRIETDEEEEEDTRGNVRWKHIRHNGLVAAQQEEEEEDDDDEEDEEEFTGVTDLVNFVFDSEQLS", "length": 1263 }, "evidence": [ { "id": "RGD:1311245", "url": "https://alliancegenome.org/gene/RGD:1311245#orthology", "database": "AGR" }, { "id": "HGNC:18118", "url": "https://alliancegenome.org/gene/HGNC:18118#orthology", "database": "AGR" }, { "id": "MGI:2682305", "url": "https://alliancegenome.org/gene/MGI:2682305#orthology", "database": "AGR" }, { "id": "FB:FBgn0026577", "url": "https://alliancegenome.org/gene/FB:FBgn0026577#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZGQ8-1", "protein_name": "Remodeling and spacing factor 1", "gene_name": "Rsf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATVAAAAAAAVAAMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDIGHGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKYLCECQFDDNLKFKNIINEEDADTMRLQPIGRDKDGLMYWYQLDQDHNVRMYIEEQDDQDGSSWKCIVRNRNELAETLALLRAQIDPVLLKNSSQQEDPSRESPTLEDEETKKDEETPKQEASRGNEKTEADERSMDSRKRSAANALEGPAVKIEKADEKELVKLPVIVKLEKPVPETEDKKIIREESDSFKENVKPIKVEAKECRVDPKDLKGSLERLGSQEPERADFGSNIKSSQDITEKSTEETEKLKNDQQAKIPLKKREIKLSDDFDSPVKGHLCKSATPTKECLKDDVKQEEETCKRVSTISALSHEGKQLMNGEMNDDKVTASLKTEQLETQLCHTKEDSSSIPAKDGSAGLEGSGVECLNSVLTSTKTSELEKEVSLGKAVDGSASDVESHSQKGRGEEPGPPNMDMPLEPSEKTTDLSLKSTLSATESCPTKIEEKAPKSKGENHTAGIECLEKVEKAKKTSVDKDIQRLSPIPEEVVRGPLESEESGLCEVAETPLPLEMTGAKEKQTSEKKGVDCLSRGSSEGQSLENASPDILRENSESSRVEMAKLDNAQTSGVEDTSQTKGSVQKNKCKYKLVSEGNSTASENTEITSERKKEGIKLTIRISSRKKKPDCPPQIVDSESKEEKAGKEEEKTSVGRTLRRSPRISRPTAKVAEIRDQKADKKRAEGEEGVEGETTSLQTADKKEHLKKAEKDTNSKASKVKPKGKVRWTGSRTRGRWKYSSNDESEGSESDKSSAASEEEEGKESEEAVLPDDDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENIIPPQEPEFSEDQEEKKKDAKKSKANVLERRSTRTRKCISYRFDEFDEAIDEAIEDDIKEADGGGVGRGKDISTITGHRGKDISTILDEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDEFKISDGSQDEFVVSDENPDESEEEPPSNEDSDTDFCSRRLRRHPSRPMRQSRRLRRKTQKKKYSDDDEEEEEEEEESEENSRDSESDFSDDFSDEFVETRRRRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEESYMSKNSEDDELTKESKRSIRKRGRSTGEYSEADEEEEEEGKPSRKRLHRIETDEESCDSAHGDADQPARESQASVLPSEQESSKKPYRIESDEEEDFENVGKVGSPLDYSLVDLPSTNGQSPGKAIENLMGKATEKSQTPKDNGTASANLAPNGTSGGQEVGAPEEDEDELLRVTDLVDYVCNSEQL", "length": 1448 }, "evidence": [ { "id": "RGD:1311245", "url": "https://alliancegenome.org/gene/RGD:1311245#orthology", "database": "AGR" }, { "id": "HGNC:18118", "url": "https://alliancegenome.org/gene/HGNC:18118#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5829", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5829#orthology", "database": "AGR" }, { "id": "MGI:2682305", "url": "https://alliancegenome.org/gene/MGI:2682305#orthology", "database": "AGR" }, { "id": "FB:FBgn0026577", "url": "https://alliancegenome.org/gene/FB:FBgn0026577#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PWW9-1", "protein_name": "Remodeling and spacing factor 1", "gene_name": "Rsf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAAAAAAAAAAAMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDIGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKYLCECQFDDNLKFKNIINEEDADTMRLQPIGRDKDGLMYWYQLDQDHNVRMYIEEQDDQDGSSWKCIVRNRNELAETLALLKAQIDPVLLKNSSQQEDSSRESPTLEDEETKKDEETPKQEASKENEKTGADERSVDSGKCSAASALEEPAVKTEKADEKELAKLPVIVKLEKPLPETEEKKIIREESDSFKENVKPIKVEAKECRADPKDLKGSLERLGSQEPERADFGSNIKSQDIIEKSTEETEKLKNDQQAKIPLKKREIKLSDDFDSPVKGPLCKSATPTKEVLKDDIKQEEETCKRVSTISALSHEGKQLVNGEINDDKVIPNFKTEQMEIQLCDTKEDSASIPAKDGNACMEGNGTECLNSVITSTKTSELEKEAPLGKGIDSSVPDIESLSQKARLEEPGLLNMDMPLEPSEKATDLSLKPTLSATEPCSTKVEEKAPRSKSENHTPGIECLERVEKAKKTSIDKDIQKLSPIPEEVVRGALESEKSGPCEVAETPLPLSMAGAKEKQTSEKKDVDCSRGSSESQSLENASPEILKEDSESSREEVAKLDNAQTSGMEDTSETKGSVQKNKFKYKLVSERNSTASENTEITSERKKEGIKLTIRISSRKKKPDCPPQTVDSESKEEKAGKEEEKASVGRTLRRSPRISRPTAKVAEIRVQKADKRRADGEDGVEGEPASLQTADKKDHLKKAEKDTNSKASKVKPKGKVRWTGSRTRGRWKYSSNDESEGSESDKSSAALEEEEGKEGEEAVLPDDDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENIIPPQEPEFSEEQEEKKKDAKKSKANALERRSTRTRKCISYRFDEFDEAIDEAIEDDIKEADGGGVGRGKDISTITGHRGKDISTILDEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDEFKISDGSQDEFVVSDENPDESEEEPPSNEDSDTDFCSRRLRRHPSRPMRQSRRLRRKTPKKKYSDDDEEEEESEENSRDSESDFSDDFSDDFVETRRRRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEESFMSKNSEDDELTKESKRSVRKRGRSTDDYSEADEDDEEEGKPSRKRLHRIETDEESCDNAHGDADQPARDSQPSALPSEQESSKKPYRIESDEEEDFENKVGSPLDYSLVDLPSTNGQSPGKAIENLMGKATEKSQTPKDNGTASASLAPNGTSGGQEVGAPEEDEDELLRVTDLVDYVCNSEQL", "length": 1441 }, "evidence": [ { "id": "RGD:1311245", "url": "https://alliancegenome.org/gene/RGD:1311245#orthology", "database": "AGR" }, { "id": "HGNC:18118", "url": "https://alliancegenome.org/gene/HGNC:18118#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5829", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5829#orthology", "database": "AGR" }, { "id": "MGI:2682305", "url": "https://alliancegenome.org/gene/MGI:2682305#orthology", "database": "AGR" }, { "id": "FB:FBgn0026577", "url": "https://alliancegenome.org/gene/FB:FBgn0026577#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96T23-1", "protein_name": "Remodeling and spacing factor 1", "gene_name": "RSF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATAAAAAAVMAPPGCPGSCPNFAVVCSFLERYGPLLDLPELPFPELERVLQAPPPDVGNGEVPKELVELHLKLMRKIGKSVTADRWEKYLIKICQEFNSTWAWEMEKKGYLEMSVECKLALLKYLCECQFDDNLKFKNIINEEDADTMRLQPIGRDKDGLMYWYQLDQDHNVRMYIEEQDDQDGSSWKCIVRNRNELAETLALLKAQIDPVLLKNSSQQDNSSRESPSLEDEETKKEEETPKQEEQKESEKMKSEEQPMDLENRSTANVLEETTVKKEKEDEKELVKLPVIVKLEKPLPENEEKKIIKEESDSFKENVKPIKVEVKECRADPKDTKSSMEKPVAQEPERIEFGGNIKSSHEITEKSTEETEKLKNDQQAKIPLKKREIKLSDDFDSPVKGPLCKSVTPTKEFLKDEIKQEEETCKRISTITALGHEGKQLVNGEVSDERVAPNFKTEPIETKFYETKEESYSPSKDRNIITEGNGTESLNSVITSMKTGELEKETAPLRKDADSSISVLEIHSQKAQIEEPDPPEMETSLDSSEMAKDLSSKTALSSTESCTMKGEEKSPKTKKDKRPPILECLEKLEKSKKTFLDKDAQRLSPIPEEVPKSTLESEKPGSPEAAETSPPSNIIDHCEKLASEKEVVECQSTSTVGGQSVKKVDLETLKEDSEFTKVEMDNLDNAQTSGIEEPSETKGSMQKSKFKYKLVPEEETTASENTEITSERQKEGIKLTIRISSRKKKPDSPPKVLEPENKQEKTEKEEEKTNVGRTLRRSPRISRPTAKVAEIRDQKADKKRGEGEDEVEEESTALQKTDKKEILKKSEKDTNSKVSKVKPKGKVRWTGSRTRGRWKYSSNDESEGSGSEKSSAASEEEEEKESEEAILADDDEPCKKCGLPNHPELILLCDSCDSGYHTACLRPPLMIIPDGEWFCPPCQHKLLCEKLEEQLQDLDVALKKKERAERRKERLVYVGISIENIIPPQEPDFSEDQEEKKKDSKKSKANLLERRSTRTRKCISYRFDEFDEAIDEAIEDDIKEADGGGVGRGKDISTITGHRGKDISTILDEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDEFKISDGSQDEFVVSDENPDESEEDPPSNDDSDTDFCSRRLRRHPSRPMRQSRRLRRKTPKKKYSDDDEEEESEENSRDSESDFSDDFSDDFVETRRRRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEESYLSKNSEDDELAKESKRSVRKRGRSTDEYSEADEEEEEEEGKPSRKRLHRIETDEEESCDNAHGDANQPARDSQPRVLPSEQESTKKPYRIESDEEEDFENVGKVGSPLDYSLVDLPSTNGQSPGKAIENLIGKPTEKSQTPKDNSTASASLASNGTSGGQEAGAPEEEEDELLRVTDLVDYVCNSEQL", "length": 1441 }, "evidence": [ { "id": "RGD:1311245", "url": "https://alliancegenome.org/gene/RGD:1311245#orthology", "database": "AGR" }, { "id": "HGNC:18118", "url": "https://alliancegenome.org/gene/HGNC:18118#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5829", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5829#orthology", "database": "AGR" }, { "id": "MGI:2682305", "url": "https://alliancegenome.org/gene/MGI:2682305#orthology", "database": "AGR" }, { "id": "FB:FBgn0026577", "url": "https://alliancegenome.org/gene/FB:FBgn0026577#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VID9-1", "protein_name": "Uncharacterized protein", "gene_name": "BEST:LD19244", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAASSAAAAAPTNPIPLPTDSISEECKDDDALTSTLHTCANDPDFAVICAFLQKFGKDLGLNLPNFKHLQEWLTNNNDVPELRDLHIKLLRKTRKTVHEKSWESALSKFCFGYSVQDAWEIERFGYRNSSLKVKLRIFRELLESQFERNAKFRAHILTLNADTLRSEPIGRDRLGHAYWLTQDAHCNLRIYQEHLDEEIWQVVATNRDEFVNLISRLRGNEVVLPSKDIGEADEDTSSSNSCHPKPPPPEQKEEEDDEEVGDEPEKTVPNLKIKLRSPEQEDQKSKKVKPLLISQAKLSSSASPAPTKKRSIEDVDSSPTASQEEQQKKHRPTLLDTKRIKKPSRYESTKDEIEEESGEEDEEEEDEEDSELDEGEEEEDVDSAAADIEEDDDEEDTGEPIEDPTIVVQGQGSGLDCEAIPYNLIGNFDYEDDLEIGEAIADPMLHVIGQGWGTDCLVGNGKNEASVEETSTRTSEPKATFFFGEPGCLKLSPMKQTSKPEAKRGIFDSLSEEKTNGESEKCIVNTPPRNGSELTKTLGDSEETASASAATLEETNICQEANVNKISDDQIKKKESVPVAKRNIQDSTISVIEKNEEISKGRTESEAIEEGVRNRTEVSVLQNNSNESDNSSIQTQDQHKVPADLNNTKKPVTEKCVLESGTVEDKLVINHQQISTNALDTACDEKLSCETESPVPNQHDSKMKSEQETATSAKESVSESSPTDGEDETAKSKCLIDPYAGKTNDKGIIINKIDKAEGVIKTLLQDDPPKDISKSETNTTCLEINISPSAEHRISEKVQTIEPSTSQNLLFEDNGKSGEVDGKSRTSGAVEEISKTSTLLNRKRRLNDSQSALRNSTSESEVHEEEPQDDDPTLDDLDVGGKRIKMRPKTTNAESRRKVEAQKTQIEETTSSSGEDDARIRRKCIAPHTKTKPTLEEIIERKLKKSIEMDLPEKTTEKVMEMPTQLMQKTREATPPIISLSPQKKTPITKPLKKNLLTQLRQEESEEETIPRKRTNSETLVPAIPASNVLCQPDERHRKRRSSEDANEAFSKESSPTEVPPSAVSEKLKRNNEQDIQEEVEDPLAMSVKDSLRSAKDQSPVPEGSARRSGRRGGPAVIHSELPQPKRTRGGARDKMQPEVNAELKQESEDDEKISTKIKSEAKDDPAPESPENRKKPEEKPIKEEPNEEPKPKVGRGRGPRKKREVDTTNIIETNDSETPVRQSRRIAQQKIKEEAERRKQEEVALRTMKQELKKKKKAEKEADPTVLEPSGEESESEASEAEEEARNKKKKKCPGKDGWSSDSEEQPESEEEEEEPPHYETDPGSPLFRSDHEFSPESELEDESQVVPMKRARTVRKENADDLEEEDAEEACQKCGKSDHPEWILLCDTPTCNKGYHCSCLSPVLFYIPEGDWHCPPCQQEQLIAALERQLEQYDTLVAQKQQERILAEEQAERERQELEAATLAAKDENFKSEKEEDEDDRDDMAVGKAEKVKRRRGDGRINRRAAKRGTRRRRGNESDSSHRKSLGSGSRSGSGSDSSSDNSTSFSDSDDEPIYKLRKRRQINVSYRLNEYDDLINSALKKEMDEVAGAGNLGRGKDISTIIEADKEKARRDDLPTEDEVGNKEDGEKDKQKSKSSGSSPSSSEDEVPLKRSNKFKQPPAKKKARKLTTLDVSSEEDHGSDEDFKTSSYSDEDTSQSASGDSDSSLEAYRRPGRGKKQRKAARRAARERRKDRKFVVEESDESEDEDQKRRTTKSKKKKDDSDYTETETEDDDDNELSDNVDSADLCDDTTSESEDGAWNPSSKKKKTVAAKKSNSSGGIARKSPKLKKLATQAEKKVKRLEYSDDDISESDLEEDDDDDEEDEEGVPLSGKGSGKQPRSQPLKPTASSTLTGKGKGKGKAKKKKQVSSEEEDGAASDDRTRTRGRRYAYIEDDDDSSDGGIKPGVHRPDTPPEERQKFIQRQEEIKRMLAEKNAEGAKIAATPRLTPLKSGVTASEKRTPGKAASGDSLSTVPLSVIRQAKVLDIDYLQRKGETIGDLDDVDESELDDAELPDDLPEDMEDAIARMVEEEEQFSAEVAARELPGAEEVLRTTPSKSKQTSRVMPESPAQNSAPSTSGLQEPHRKRLPMPTMHPPLLRHQFPISAGPSHSPASLVPPHAAQGMHPMLQRHLSQTVPPPQAMHLLQNALSAPLGQPLGCGNYGSGPNSAQHLPLVMSMPSAAAAAAHLMQSAVASATARPVETASGNPASDPKPRGRRKKVTPLRDQLQKQQTAAAVTAATSSTTPGSAPSEKVKAQPLFKPHEDAAPSAPASQASVITRMPSLLPPAHGRNHGPPSGLYPSSADLARFYGQVANQQPIPAVPGSRSPSSTSGPPRHLLRPQMPPGLPPPHASLRPTYGPPPPLRGSGPPTSTPSTTTNSRPAYLHGAEHHGGPSGPPMGGVFSSGPPPARHATPHLNPYRAPPIYGNPNYSPRLGGAPGTGSMRPGAVDYVAGPRGYSPYGYYPPPPPLSTPSAHAATSSVIVSAPHTLTPTNHSVPTLTHGKTPPQQTPTQSSGPPPAAAPPPTITSETSSHKPPLASVITSKKLTTLEAYPIRKSPIAVVADVSGPAEPTRSPAPIAEEDSGSAHDTRAPSSATGTAVVGEFSGLVSYFSSQQDDYDT", "length": 2663 }, "evidence": [ { "id": "RGD:1311245", "url": "https://alliancegenome.org/gene/RGD:1311245#orthology", "database": "AGR" }, { "id": "HGNC:18118", "url": "https://alliancegenome.org/gene/HGNC:18118#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5829", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5829#orthology", "database": "AGR" }, { "id": "MGI:2682305", "url": "https://alliancegenome.org/gene/MGI:2682305#orthology", "database": "AGR" }, { "id": "FB:FBgn0026577", "url": "https://alliancegenome.org/gene/FB:FBgn0026577#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0" } ], "pmid": "" }, { "name": "histone binding", "id": "GO:0042393", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042393", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "RSF complex", "id": "GO:0031213", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031213", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1173, "end_pos": 1175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1232, "end_pos": 1234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1272, "end_pos": 1274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1669, "end_pos": 1671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 176, "end_pos": 178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 730, "end_pos": 732, "annotation": "n_glycosylation_sequon" }, { "start_pos": 877, "end_pos": 879, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z8X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0" }, { "id": "PS50827", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50827" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DDT", "eco_id": "ECO_0000259", "start_pos": 100, "end_pos": 161, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z8X0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X0" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 1505, "end_pos": 1555, "start_aa": "Asp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1173, "end_pos": 1175 }, { "start_pos": 1232, "end_pos": 1234 }, { "start_pos": 1272, "end_pos": 1274 }, { "start_pos": 1669, "end_pos": 1671 }, { "start_pos": 176, "end_pos": 178 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 505, "end_pos": 507 }, { "start_pos": 730, "end_pos": 732 }, { "start_pos": 877, "end_pos": 879 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 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"https://monarchinitiative.org/disease/MONDO:0012269", "name": "3q29 deletion syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060419", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060419" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2F3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2F3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-16n15.6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2F3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110411-70", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-70", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z2F3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z2F3", "database": "AlphaFoldDB", "categories": [] }, { "id": "799052", "url": "https://www.ncbi.nlm.nih.gov/gene/799052", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:799052", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799052", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z2F3", "url": "https://www.orthodb.org/?gene=A0A8M6Z2F3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23423", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23423", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213097", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2F3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2F3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110411-70", "url": "https://zfin.org/ZDB-GENE-110411-70", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRNRNCTLMGGGIPLSSEFFKVIKDDLWLFLLPAVFAVLLLALFLEEIGFFLRHVPSHRRKRLSLWILGVYPVFGMTSIISLYVPRSSSLCNFIASLYHSITLLKFMGLIKNFFGGNTRMLEALAGEQVSPNPFPCCCCCCLPLFDINKTSVSWMMAAVLQLSVVRTILFFLTLVLWTDEQYDYGDVNSVNLNMYVNAIIAISTFLSFYGYLLFYKATKRALPGHGLRAKFICIIVVLVLCGLQSGVLETMGALNVIPCTPPFSDLFRSQLIYHYSIIVEMFCISLFAHYTFRKVEPCQDVAEEMEVDVLRVFNEKSIQTEEELPIAVQLSSQEDDAFHSNLGYNSDSEDSSLCKIEHAPLDRFTFPSQHRMQTAANTEKVHTPPPEDSMRVKMPTITVSAQINHVDNGDVTVV", "length": 414, "header": "tr|A0A8M6Z2F3-1|A0A8M6Z2F3_DANRE Isoform 1 of Organic solute transporter subunit alpha OS=Danio rerio OX=7955 GN=si:dkey-16n15.6 PE=4 SV=1 CANONICAL=A0A8M6Z2F3-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z2F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2F3/entry#A0A8M6Z2F3-1", "sequence": { "sequence": "MRNRNCTLMGGGIPLSSEFFKVIKDDLWLFLLPAVFAVLLLALFLEEIGFFLRHVPSHRRKRLSLWILGVYPVFGMTSIISLYVPRSSSLCNFIASLYHSITLLKFMGLIKNFFGGNTRMLEALAGEQVSPNPFPCCCCCCLPLFDINKTSVSWMMAAVLQLSVVRTILFFLTLVLWTDEQYDYGDVNSVNLNMYVNAIIAISTFLSFYGYLLFYKATKRALPGHGLRAKFICIIVVLVLCGLQSGVLETMGALNVIPCTPPFSDLFRSQLIYHYSIIVEMFCISLFAHYTFRKVEPCQDVAEEMEVDVLRVFNEKSIQTEEELPIAVQLSSQEDDAFHSNLGYNSDSEDSSLCKIEHAPLDRFTFPSQHRMQTAANTEKVHTPPPEDSMRVKMPTITVSAQINHVDNGDVTVV", "length": 414, "header": "tr|A0A8M6Z2F3-1|A0A8M6Z2F3_DANRE Isoform 1 of Organic solute transporter subunit alpha OS=Danio rerio OX=7955 GN=si:dkey-16n15.6 PE=4 SV=1 CANONICAL=A0A8M6Z2F3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:799052", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799052", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L452-1", "protein_name": "Solute carrier family 51 member A", "gene_name": "Slc51a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLLDHPGLLTRYTADLLELLETNYSISPACFSHPPTAAQLLRELGSVEIALTIILTFFTIGSVAIFLEDAIYLYKNTLCPIKKRTLIWSSSAPTVVSVFCCFGLWIPRALTLVEMAITSFYAVCFYLLMMVMVEGFGGKEAVLRTLKDTPMRVHTGPCCCCCPCCPPLILTRKKLQLLMLGPFQYAFFKIVMSIVGLFLIPDGIYDPAEISEKSAALWISNFLAVSTLLALWSLAILFRQAKLHLGEQNMGSKFALFQVLVILTALQPSIFSILANSGQIACSPPYSSKIRSQVMNCHMLILETFLLTVLTRMYYRKKDNKVGYEACLPPDLDSTLKA", "length": 340 }, "evidence": [ { "id": "FB:FBgn0036834", "url": "https://alliancegenome.org/gene/FB:FBgn0036834#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66I08-1", "protein_name": "Organic solute transporter subunit alpha", "gene_name": "slc51a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METSNFTLFDPRCRAEAPFAIDAIKQLDIFGKVLYTVLTLMATASMLVFIEECIYIYKKVPAHKKSTIIWVTGVAPVMAIMSCLGMWVPRATMFTDMTSATYFAIVVFKFLILMIEEVGGDNAFLRRCEKQTFKISTGPCCCCCPCLPNVPITRRSLFILKLGSYQFALMKLVLTIFSIVLWTNGSFSLTNVSASGAAIWINSFIGVLTIIALWPVAIMFMHVREALRTLKIVPKYAMYQLVLILSQLQTAIINILALNGTIACSPPYSSQARGYMMSQQLLIVEMFIITLVTRVLYRRQYEPIPEPDDVEEKKTVLSSKKAIDVA", "length": 326 }, "evidence": [ { "id": "FB:FBgn0036834", "url": "https://alliancegenome.org/gene/FB:FBgn0036834#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q86UW1-1", "protein_name": "Organic solute transporter subunit alpha", "gene_name": "SLC51A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPGRTQIKLDPRYTADLLEVLKTNYGIPSACFSQPPTAAQLLRALGPVELALTSILTLLALGSIAIFLEDAVYLYKNTLCPIKRRTLLWKSSAPTVVSVLCCFGLWIPRSLVLVEMTITSFYAVCFYLLMLVMVEGFGGKEAVLRTLRDTPMMVHTGPCCCCCPCCPRLLLTRKKLQLLMLGPFQYAFLKITLTLVGLFLVPDGIYDPADISEGSTALWINTFLGVSTLLALWTLGIISRQARLHLGEQNMGAKFALFQVLLILTALQPSIFSVLANGGQIACSPPYSSKTRSQVMNCHLLILETFLMTVLTRMYYRRKDHKVGYETFSSPDLDLNLKA", "length": 340 }, "evidence": [ { "id": "FB:FBgn0036834", "url": "https://alliancegenome.org/gene/FB:FBgn0036834#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R000-1", "protein_name": "Organic solute transporter subunit alpha", "gene_name": "Slc51a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGRTHIKLDPRYTAELLELLETNYSISPACFSHPPTAAQLLRALGPVDIALTIILTFLTTGSVAIFLEDAVYLYKNTLCPIKKRTLIWSSSAPTVVSVFCCFGLWIPRALTLVEMAITSFYAVCFYLLMMVMVEGFGGKKAVLRTLKDTPMRVHTGPCCCCCPCCPPLILTRKKLQLLLLGPFQYAFFKITLSIVGLFLIPDGIYDPGEISEKSAALWINNLLAVSTLLALWSLAILFRQAKMHLGEQNMGSKFALFQVLVILTALQPAIFSILANSGQIACSPPYSSKIRSQVMNCHMLILETFLMTVLTRMYYRRKDDKVGYEACSLPDLDSALKA", "length": 340 }, "evidence": [ { "id": "FB:FBgn0036834", "url": "https://alliancegenome.org/gene/FB:FBgn0036834#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VVV2-1", "protein_name": "Organic solute transporter alpha-like protein", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNASENYFTMDPTENISQVLDQNRNNTNSLRTHPTVEEYYENMTAFLSLAIFIASLLTILNISIFATTVSRLRRHLDKPLLGPSIMMVGLYPIISVAALVTILVPYSWFICHTVMHVMFMVGGPVFRTLLFRYVGSEQNYVKETAGEAVQLNTPPCCCCCLCLPMVIPTKAKLCISRYMVWQMPFWQGSIMLVMNILYYRDIQLYRQVMFFFIPFIVCSIVLGAWSLQITVRMITKVRGDYQLRKKMFCLQLVVMLCKLQYLVLYDQLDGIKMGGEYPINHTVYKQTIINILILVEMVLVSMMVQSAYRTPVQVQIDEVNKEKEVTRI", "length": 328 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-110411-70", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-70#orthology", "database": "AGR" }, { "id": "FB:FBgn0036834", "url": "https://alliancegenome.org/gene/FB:FBgn0036834#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2F3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2F3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2F3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2F3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z345-1", "uniprot_ac": "A0A8M6Z345", "uniprot_id": "A0A8M6Z345_DANRE", "mass": { "chemical_mass": 15188.0, "monoisotopic_mass": 15188.0 }, "refseq": { "ac": "XP_017207845", "name": "cytochrome c oxidase assembly factor 1 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207845" }, "gene_names": [ { "name": "coa1", "type": "recommended", "evidence": [ { "id": "A0A8M6Z345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345" } ] }, { "name": "rpl37", "type": "recommended", "evidence": [ { "id": "A0A8M6Z345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345" } ] }, { "name": "coa1", "type": "synonym", "evidence": [ { "id": "XP_017207845", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207845" }, { "id": "A0A8M6Z345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase assembly factor 1 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z345", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345/entry#names_and_taxonomy" } ] }, { "name": "cytochrome c oxidase assembly factor 1 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017207845", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207845" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017207845", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207845" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z345", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "coa1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040625-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040625-39", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ZFIN:ZDB-GENE-070912-694", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-694", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z345", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z345", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000076360", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000076360", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "108179075", "url": "https://www.ncbi.nlm.nih.gov/gene/108179075", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108179075", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179075", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RQCWCLQ", "url": "https://omabrowser.org/oma/group/RQCWCLQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z2I9", "url": "https://www.orthodb.org/?gene=A0A8M6Z2I9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z345", "url": "https://www.orthodb.org/?gene=A0A8M6Z345", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "B0S673", "url": "https://www.orthodb.org/?gene=B0S673", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47148", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47148", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47148:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47148:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08695", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08695", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017207845", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207845", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2I9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2I9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2I9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z345", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z345-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S673", "url": "https://www.uniprot.org/uniprotkb/B0S673", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S673-1", "url": "https://www.uniprot.org/uniprotkb/B0S673-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040625-39", "url": "https://zfin.org/ZDB-GENE-040625-39", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] }, { "id": "ZDB-GENE-070912-694", "url": "https://zfin.org/ZDB-GENE-070912-694", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSRSTSLLQQMTIFMTVVTGGGCATMYYLMQKNFAKSEYYRQALEQLNSNSTAMASLGAPPLKIHNIHLSDRHNRIDHSSAQLKIPVTGSKTGGYLYTTSTRDSLTNSRWHLQQVVLKLRKGDTVEIFNNTQSEE", "length": 135, "header": "tr|A0A8M6Z345-1|A0A8M6Z345_DANRE Isoform 1 of Cytochrome c oxidase assembly factor 1 homolog isoform X1 OS=Danio rerio OX=7955 GN=coa1 PE=1 SV=1 CANONICAL=A0A8M6Z345-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z2I9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345/entry#A0A8M6Z2I9-1", "sequence": { "sequence": "MSRSTSLLQQMTIFMTVVTGGGCATMYYLMQKNFAKSEYYRQALEQLNSNSTAMASLGAPPLKIHNIHLSDRHNRIDHSSAQLKIPVTGSKTGGYLYTTSTRDSLTNSPLLSVDGTCSRSS", "length": 121, "header": "tr|A0A8M6Z2I9-1|A0A8M6Z345_DANRE Computationally mapped isoform of Cytochrome c oxidase assembly factor 1 homolog isoform X1 OS=Danio rerio OX=7955 GN=coa1 PE=1 SV=1 CANONICAL=A0A8M6Z345-1" }, "locus": {} }, { "isoform_ac": "A0A8M6Z345-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345/entry#A0A8M6Z345-1", "sequence": { "sequence": "MSRSTSLLQQMTIFMTVVTGGGCATMYYLMQKNFAKSEYYRQALEQLNSNSTAMASLGAPPLKIHNIHLSDRHNRIDHSSAQLKIPVTGSKTGGYLYTTSTRDSLTNSRWHLQQVVLKLRKGDTVEIFNNTQSEE", "length": 135, "header": "tr|A0A8M6Z345-1|A0A8M6Z345_DANRE Isoform 1 of Cytochrome c oxidase assembly factor 1 homolog isoform X1 OS=Danio rerio OX=7955 GN=coa1 PE=1 SV=1 CANONICAL=A0A8M6Z345-1" }, "locus": {} }, { "isoform_ac": "B0S673-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345/entry#B0S673-1", "sequence": { "sequence": "MSRSTSLLQQMTIFMTVVTGGGCATMYYLMQKNFAKSEYYRQALEQLNSNSTAMASLGAPPLKIHNIHLSDRHNRIDHSSAQLKIPVTGSKTGGYLYTTSTRDSLTNRWHLQQVVLKLRKGDTVEIFNNTQSEE", "length": 134, "header": "tr|B0S673-1|B0S673_DANRE Computationally mapped isoform of Cytochrome c oxidase assembly factor 1 homolog isoform X2 OS=Danio rerio OX=7955 GN=rpl37 PE=1 SV=1 CANONICAL=A0A8M6Z345-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108179075", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179075", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0ZGJ3-1", "protein_name": "Cytochrome c oxidase assembly factor 1", "gene_name": "COA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVPLGKLVFFSSVATSGTCTLLYFLIQKMFSRASYYQLALEHLHSHAEALEALGTPLSVHYLQLTDKYNFEDIADAQLRIPVSGPKSEGHLYVSSSREGPFRRWNLQEVFLELRDGHRIPVFKPSGEGPAR", "length": 132 }, "evidence": [ { "id": "A0A8M6Z345", "url": "https://omabrowser.org/oma/group/A0A8M6Z345/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A7Z2-1", "protein_name": "Ribosomal protein L37", "gene_name": "Rpl37-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKGTSSFGKRRHKTHTLCRRCGSKAYHLQKSTCGKCAYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "length": 97 }, "evidence": [ { "id": "HGNC:10347", "url": "https://alliancegenome.org/gene/HGNC:10347#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P49166-1", "protein_name": "Large ribosomal subunit protein eL37A", "gene_name": "RPL37A", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPAAKTRSYNWGAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSASKASA", "length": 88 }, "evidence": [ { "id": "HGNC:10347", "url": "https://alliancegenome.org/gene/HGNC:10347#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P51402-1", "protein_name": "Large ribosomal subunit protein eL37B", "gene_name": "RPL37B", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGKGTPSFGKRHNKSHTLCNRCGRRSFHVQKKTCSSCGYPSAKTRSHNWAAKAKRRHTTGTGRMRYLKHVSRRFKNGFQTGSAKATSA", "length": 88 }, "evidence": [ { "id": "HGNC:10347", "url": "https://alliancegenome.org/gene/HGNC:10347#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P61927-1", "protein_name": "Large ribosomal subunit protein eL37", "gene_name": "RPL37", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "length": 97 }, "evidence": [ { "id": "HGNC:10347", "url": "https://alliancegenome.org/gene/HGNC:10347#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040625-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040625-39#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P61928-1", "protein_name": "Large ribosomal subunit protein eL37", "gene_name": "Rpl37", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "length": 97 }, "evidence": [ { "id": "HGNC:10347", "url": "https://alliancegenome.org/gene/HGNC:10347#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IPK2-1", "protein_name": "Cytochrome c oxidase assembly factor 1 homolog", "gene_name": "NEST:bs35c08", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPTLKLRIGLPSKRTMGSICICGALASISGLAYMRWRLEDRVRQTEFYQLAIQQLRQHSGAVGLLGEPIKESGFNLSNEKNRCDEDKAQLQFHVQGPKDRGTVYFWASNNQKQGWLIDRLELETRQNPNTRYLLKKPPNYSLVSSDGDPDPPNAESSEETQQPQTPLEPQEQMEMEDKEQEPTVHQHPSIQNNPPQQLHQQQGQEPVPHVHTAEG", "length": 215 }, "evidence": [ { "id": "HGNC:21868", "url": "https://alliancegenome.org/gene/HGNC:21868#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-694", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-694#orthology", "database": "AGR" }, { "id": "FB:FBgn0051913", "url": "https://alliancegenome.org/gene/FB:FBgn0051913#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9D823-1", "protein_name": "Large ribosomal subunit protein eL37", "gene_name": "Rpl37", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKGTSSFGKRRNKTHTLCRRCGSKAYHLQKSTCGKCGYPAKRKRKYNWSAKAKRRNTTGTGRMRHLKIVYRRFRHGFREGTTPKPKRAAVAASSSS", "length": 97 }, "evidence": [ { "id": "HGNC:10347", "url": "https://alliancegenome.org/gene/HGNC:10347#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZY4-1", "protein_name": "Cytochrome c oxidase assembly factor 1 homolog", "gene_name": "COA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMWQKYAGSRRSMPLGARILFHGVFYAGGFAIVYYLIQKFHSRALYYKLAVEQLQSHPEAQEALGPPLNIHYLKLIDRENFVDIVDAKLKIPVSGSKSEGLLYVHSSRGGPFQRWHLDEVFLELKDGQQIPVFKLSGENGDEVKKE", "length": 146 }, "evidence": [ { "id": "HGNC:21868", "url": "https://alliancegenome.org/gene/HGNC:21868#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-694", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-694#orthology", "database": "AGR" }, { "id": "FB:FBgn0051913", "url": "https://alliancegenome.org/gene/FB:FBgn0051913#orthology", "database": "AGR" }, { "id": "FB:FBgn0034578", "url": "https://alliancegenome.org/gene/FB:FBgn0034578#orthology", "database": "AGR" }, { "id": "A0A8M6Z345", "url": "https://omabrowser.org/oma/group/A0A8M6Z345/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VXX8-1", "protein_name": "Large ribosomal subunit protein eL37A", "gene_name": "RpL37-1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTKGTSSFGKRHNKTHTLCRRCGRSSYHIQKSTCAQCGYPAAKLRSYNWSVKAKRRKTTGTGRMQHLKVVRRRFRNGFREGTQAKPKKAVASK", "length": 93 }, "evidence": [ { "id": "HGNC:10347", "url": "https://alliancegenome.org/gene/HGNC:10347#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W1U6-1", "protein_name": "Large ribosomal subunit protein L37-2", "gene_name": "RpL37-2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTKGTTSFGKRHNKTHTICRRCGNSSYHLQKSKCSQCGYPAAKTRSFNWSRKAKGRKAQGTGRMRYLKNLRRRFRNGLREGGAAKKKTN", "length": 89 }, "evidence": [ { "id": "HGNC:10347", "url": "https://alliancegenome.org/gene/HGNC:10347#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2M9-1", "protein_name": "Cytochrome c oxidase assembly factor 1 homolog", "gene_name": "Dmel\\CG15653", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVGLKFPSNRTLGNICVYGAVASISAVMYMKWKMEDRVKSAEYYKLALKALRSHRGAVGLLGEPIKDSGIDLSNANNNCNAEEARCEVAVRGSKDKGTLYFWASNQPDRGWLIDRLELETKLNPEKRFLLKKSEELTFDLPESITKQTAQQVDSNVILSASDQQPETHSK", "length": 170 }, "evidence": [ { "id": "HGNC:21868", "url": "https://alliancegenome.org/gene/HGNC:21868#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-694", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-694#orthology", "database": "AGR" }, { "id": "FB:FBgn0034578", "url": "https://alliancegenome.org/gene/FB:FBgn0034578#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z345", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial respiratory chain complex I assembly", "id": "GO:0032981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z345", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345" } ], "pmid": "" }, { "name": "mitochondrial respiratory chain complex IV assembly", "id": "GO:0033617", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033617", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z345", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z345" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z2M6-1", "uniprot_ac": "A0A8M6Z2M6", "uniprot_id": "A0A8M6Z2M6_DANRE", "mass": { "chemical_mass": 61650.0, "monoisotopic_mass": 61650.0 }, "refseq": { "ac": "XP_017213243", "name": "solute carrier family 23 member 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213243" }, "gene_names": [ { "name": "slc23a3", "type": "recommended", "evidence": [ { "id": "A0A8M6Z2M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2M6" } ] }, { "name": "slc23a3", "type": "synonym", "evidence": [ { "id": "XP_017213243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213243" } ] } ], "protein_names": [ { "name": "Solute carrier family 23 member 3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z2M6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2M6/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 23 member 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017213243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213243" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017213243.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213243" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2M6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2M6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "slc23a3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2M6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-714", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-714", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z2M6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z2M6", "database": "AlphaFoldDB", "categories": [] }, { "id": "100333020", "url": "https://www.ncbi.nlm.nih.gov/gene/100333020", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100333020", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333020", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z2M6", "url": "https://www.orthodb.org/?gene=A0A8M6Z2M6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00860", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00860", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213243", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2M6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2M6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2M6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GFS0", "url": "https://www.uniprot.org/uniprotkb/A0AC58GFS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GFS0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GFS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-714", "url": "https://zfin.org/ZDB-GENE-070912-714", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVQTDRCKRPLDLEKPEGNGSLDVDCRPSILLNFALALQHVLVLSSLCALVVCTLIQEVERDTIVAYVLFHSGISTLLQSWIGSRLPLIQAPSLDFLIPAMALLSDQSGSAVSCRGQCVEPQEPVAPANPIRELRGMVVVAGVVQLAAGSTGLGGFALGRCGPLVLAPLLCILGFSIYKEAALLCSDHWGLAILAVVLLVILSQHLHSFLHLSVLSVCRRLSVLLSVMVTWVVCAALSHWGHVHLNSVTEMISINTNATFNQYQNSPQSIHKLIIHNGSLPWLDFPLPASSLPLLSGRSVAAGLAGGLSASMSSPAVYVLCARLLKAPVPPAHACNRGLCVDGLGSVFAGLMGAPVGLCSSASNACVIGLSQSGSRSTVQLAGVSLLILGLSPQLAQMLCSVPLAIHGAVLSVTYALAVATGITYFQHADVDSGRNIFNIGFTMFMSLALPHWFRLHSGFIQTGVGSVDVFLQSLLTLPVFLVGVLAFLLEHTVSGTLPERGLVRQEGTKKIQSFADQQQGYSHSPDPVYDPPAPVMKVLNLTGFRTVLFCACRTHTVEEVLVTEPEMSSLLPDKDTGACNG", "length": 582, "header": "tr|A0A8M6Z2M6-1|A0A8M6Z2M6_DANRE Isoform 1 of Solute carrier family 23 member 3 isoform X1 OS=Danio rerio OX=7955 GN=slc23a3 PE=3 SV=1 CANONICAL=A0A8M6Z2M6-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z2M6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2M6/entry#A0A8M6Z2M6-1", "sequence": { "sequence": "MVQTDRCKRPLDLEKPEGNGSLDVDCRPSILLNFALALQHVLVLSSLCALVVCTLIQEVERDTIVAYVLFHSGISTLLQSWIGSRLPLIQAPSLDFLIPAMALLSDQSGSAVSCRGQCVEPQEPVAPANPIRELRGMVVVAGVVQLAAGSTGLGGFALGRCGPLVLAPLLCILGFSIYKEAALLCSDHWGLAILAVVLLVILSQHLHSFLHLSVLSVCRRLSVLLSVMVTWVVCAALSHWGHVHLNSVTEMISINTNATFNQYQNSPQSIHKLIIHNGSLPWLDFPLPASSLPLLSGRSVAAGLAGGLSASMSSPAVYVLCARLLKAPVPPAHACNRGLCVDGLGSVFAGLMGAPVGLCSSASNACVIGLSQSGSRSTVQLAGVSLLILGLSPQLAQMLCSVPLAIHGAVLSVTYALAVATGITYFQHADVDSGRNIFNIGFTMFMSLALPHWFRLHSGFIQTGVGSVDVFLQSLLTLPVFLVGVLAFLLEHTVSGTLPERGLVRQEGTKKIQSFADQQQGYSHSPDPVYDPPAPVMKVLNLTGFRTVLFCACRTHTVEEVLVTEPEMSSLLPDKDTGACNG", "length": 582, "header": "tr|A0A8M6Z2M6-1|A0A8M6Z2M6_DANRE Isoform 1 of Solute carrier family 23 member 3 isoform X1 OS=Danio rerio OX=7955 GN=slc23a3 PE=3 SV=1 CANONICAL=A0A8M6Z2M6-1" }, "locus": {} }, { "isoform_ac": "A0AC58GFS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2M6/entry#A0AC58GFS0-1", "sequence": { "sequence": "MVTWVVCAALSHWGHVHLNSVTEMISINTNATFNQYQNSPQSIHKLIIHNGSLPWLDFPLPASSLPLLSGRSVAAGLAGGLSASMSSPAVYVLCARLLKAPVPPAHACNRGLCVDGLGSVFAGLMGAPVGLCSSASNACVIGLSQSGSRSTVQLAGVSLLILGLSPQLAQMLCSVPLAIHGAVLSVTYALAVATGITYFQHADVDSGRNIFNIGFTMFMSLALPHWFRLHSGFIQTGVGSVDVFLQSLLTLPVFLVGVLAFLLEHTVSGTLPERGLVRQEGTKKIQSFADQQQGYSHSPDPVYDPPAPVMKVLNLTGFRTVLFCACRTHTVEEVLVTEPEMSSLLPDKDTGACNG", "length": 355, "header": "tr|A0AC58GFS0-1|A0AC58GFS0_DANRE Computationally mapped isoform of Solute carrier family 23 member 3 isoform X2 OS=Danio rerio OX=7955 GN=slc23a3 PE=3 SV=1 CANONICAL=A0A8M6Z2M6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100333020", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333020", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZG28-1", "protein_name": "Solute carrier family 23, member 3", "gene_name": "Slc23a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSPPHPIPLLSVGSQDTPAPRPPLLPPLQDPSSRSWASWCGPSTWGLSCLLALQHFLVLTSLLWASHLLLLHSLPPGGLSYPPAQLLASSFFSCGMSTVLQTWMGSRLPLIQAPSLEFLIPALVLTNQKLPLMTKTPGNASLSLRLCSLTRSCHGPELWNTSLREVSGAVVMSGLLQGTMGLLGVPGRVFPYCGPLVLAPSLVVAGLSAHKEVAQFCSAHWGLALLLILLMVVCSQHLGSCQVPLCSWRPASTSSTHIYIPIFRLLSVLAPVACVWLISACLGLSVIPLQLSEPSDAPWFWLPHPGEWEWPLLTPKALAAGISMALAASTSSLGCYALCGQLLHLSPPPPHACSRGLSLEGLGSVLAGLLGSPLGTASSFPNVGTVSLFQTGSRRVAHLVGLFCMGLGLSPRLAQLFTNIPLPVLGGVLGVTQAVVLSAGFSSFHLADIDSGRNVFIVGFSIFMALLLPRWLREAPILLNTGWSPMDMFLRSLLAEPIFLAGLLGFLLENTISGTRIERGLGQALPTSFTAQETQMLQKSRKKAAQEYGLPLSIKNLCSCIPQPLRCLCPMPEDSGDEGGSSKTGETADLLPNSGESSSPDGREGFRS", "length": 610 }, "evidence": [ { "id": "HGNC:20601", "url": "https://alliancegenome.org/gene/HGNC:20601#orthology", "database": "AGR" }, { "id": "RGD:1307402", "url": "https://alliancegenome.org/gene/RGD:1307402#orthology", "database": "AGR" }, { "id": "MGI:104516", "url": "https://alliancegenome.org/gene/MGI:104516#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-714", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-714#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q60850-1", "protein_name": "Solute carrier family 23 member 3", "gene_name": "Slc23a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRSPLHPIPLLSEGYQDTPAPLPPLLPPLQNPSSRSWASRVFGPSTWGLSCLLALQHFLVLASLLWASHLLLLHGLPPGGLSYPPAQLLASSFFSCGLSTVLQTWMGSRLPLIQAPSLEFLIPALVLTNQKLPLTTKTPGNASLSLPLCSLTRSCHGLELWNTSLREVSGAVVVSGLLQGTIGLLGVPGRVFPYCGPLVLAPSLVVAGLSAHKEVAQFCSAHWGLALLLILLMVVCSQHLGSCQIPLCSWRPSSTSTHICIPVFRLLSVLAPVACVWFISAFVGTSVIPLQLSEPSDAPWFWLPHPGEWEWPLLTPRALAAGISMALAASTSSLGCYALCGQLLRLSPPPPHACSRGLSLEGLGSVLAGLLGSPLGTASSFPNVGTVSLFQTGSRRVAHLVGLFCMGLGLSPRLAQLFTSIPLPVLGGVLGVTQAVVLSAGFSSFHLADIDSGRNVFIVGFSIFMALLLPRWLREAPVLLNTGWSPLDMFLRSLLAEPIFLAGLLGFLLENTISGTRAERGLGQRLPTSFTAQEIQMLQQSRRKAAQEYGLPLPIKNLCSCIPQPLHCLCPMPEDSGDEGGSSKTGERADLLPNSGESYSTASREGVRSQ", "length": 611 }, "evidence": [ { "id": "HGNC:20601", "url": "https://alliancegenome.org/gene/HGNC:20601#orthology", "database": "AGR" }, { "id": "RGD:1307402", "url": "https://alliancegenome.org/gene/RGD:1307402#orthology", "database": "AGR" }, { "id": "MGI:104516", "url": "https://alliancegenome.org/gene/MGI:104516#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-714", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-714#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6PIS1-1", "protein_name": "Solute carrier family 23 member 3", "gene_name": "SLC23A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSPLNPSQLRSVGSQDALAPLPPPAPQNPSTHSWDPLCGSLPWGLSCLLALQHVLVMASLLCVSHLLLLCSLSPGGLSYSPSQLLASSFFSCGMSTILQTWMGSRLPLVQAPSLEFLIPALVLTSQKLPRAIQTPGNSSLMLHLCRGPSCHGLGHWNTSLQEVSGAVVVSGLLQGMMGLLGSPGHVFPHCGPLVLAPSLVVAGLSAHREVAQFCFTHWGLALLVILLMVVCSQHLGSCQFHVCPWRRASTSSTHTPLPVFRLLSVLIPVACVWIVSAFVGFSVIPQELSAPTKAPWIWLPHPGEWNWPLLTPRALAAGISMALAASTSSLGCYALCGRLLHLPPPPPHACSRGLSLEGLGSVLAGLLGSPMGTASSFPNVGKVGLIQAGSQQVAHLVGLLCVGLGLSPRLAQLLTTIPLPVVGGVLGVTQAVVLSAGFSSFYLADIDSGRNIFIVGFSIFMALLLPRWFREAPVLFSTGWSPLDVLLHSLLTQPIFLAGLSGFLLENTIPGTQLERGLGQGLPSPFTAQEARMPQKPREKAAQVYRLPFPIQNLCPCIPQPLHCLCPLPEDPGDEEGGSSEPEEMADLLPGSGEPCPESSREGFRSQK", "length": 610 }, "evidence": [ { "id": "HGNC:20601", "url": "https://alliancegenome.org/gene/HGNC:20601#orthology", "database": "AGR" }, { "id": "RGD:1307402", "url": "https://alliancegenome.org/gene/RGD:1307402#orthology", "database": "AGR" }, { "id": "MGI:104516", "url": "https://alliancegenome.org/gene/MGI:104516#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-714", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-714#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2M6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2M6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2M6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2M6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 19, "end_pos": 21 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 277, "end_pos": 279 }, { "start_pos": 541, "end_pos": 543 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z2N0-1", "uniprot_ac": "A0A8M6Z2N0", "uniprot_id": "A0A8M6Z2N0_DANRE", "mass": { "chemical_mass": 62593.0, "monoisotopic_mass": 62593.0 }, "refseq": { "ac": "XP_017207958", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207958" }, "gene_names": [ { "name": "LOC100536182", "type": "recommended", "evidence": [ { "id": "A0A8M6Z2N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0" } ] }, { "name": "LOC100536182", "type": "synonym", "evidence": [ { "id": "XP_017207958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207958" } ] } ], "protein_names": [ { "name": "Ras-related protein Rab-25", "type": "recommended", "evidence": [ { "id": "A0A8M6Z2N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017207958", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207958" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017207958.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017207958", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207958" } ] }, { "annotation": "The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. RAB25 regulates epithelial cell differentiation, proliferation and survival, thereby playing key roles in tumorigenesis. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia. Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions. May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0#function" }, { "database": "UniProtKB", "id": "ARBA00055320", "url": "https://www.uniprot.org/uniprotkb/ARBA00055320#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100536182", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0", "locus": {} } ], "crossref": [ { "id": "cd01868", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01868", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19769", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19769", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100536182", "url": "https://www.ncbi.nlm.nih.gov/gene/100536182", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001806", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001806", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein 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"tr|A0A8M6Z2N0-1|A0A8M6Z2N0_DANRE Isoform 1 of Ras-related protein Rab-25 OS=Danio rerio OX=7955 GN=LOC100536182 PE=3 SV=3 CANONICAL=A0A8M6Z2N0-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z2N0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0/entry#A0A8M6Z2N0-1", "sequence": { "sequence": "MAESSFSVAQEEFSCAVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQELNPGNQHKVTEATHKLQEMICQQHKKLLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTELQSRLRETQSSFQQKIQERQKELEELREAVESHKHSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFIINSQPAFDQVDESVSRLRDKLQQFCTEEMKTISSTVRIISIISTPEPKAQKEFLFKFVLIGDSGVGKSNLLSRFTQNEFNLETKSTIGVDFVTKRIQVDGKTIKAQIWDTAGQERFRAITSAYYRGVAGALLVYDITKHLTYKNVERWLKELRKHADNNIFIMLVGNKSDLQHLRAVPTDKARAFAEKNNLSFIETSALDSTNVEEAFKNILTEIYRNVSKKQVGS", "length": 551, "header": "tr|A0A8M6Z2N0-1|A0A8M6Z2N0_DANRE Isoform 1 of Ras-related protein Rab-25 OS=Danio rerio OX=7955 GN=LOC100536182 PE=3 SV=3 CANONICAL=A0A8M6Z2N0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "A0A8M6Z2N0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M6Z2N0" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0A8M6Z2N0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M6Z2N0" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:100536182", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536182", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "pseudopodium membrane", "id": "GO:0031260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031260", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 515, "end_pos": 517, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z2N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 189, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z2N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N0" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 58, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 492, "end_pos": 494 }, { "start_pos": 515, "end_pos": 517 }, { "start_pos": 543, "end_pos": 545 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", 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"sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M6Z2N2-1", "uniprot_ac": "A0A8M6Z2N2", "uniprot_id": "A0A8M6Z2N2_DANRE", "mass": { "chemical_mass": 88568.0, "monoisotopic_mass": 88568.0 }, "refseq": { "ac": "XP_017214532", "name": "protocadherin alpha-3-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214532" }, "gene_names": [ { "name": "LOC108192084", "type": "recommended", "evidence": [ { "id": "A0A8M6Z2N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2" } ] }, { "name": "LOC108192084", "type": "synonym", "evidence": [ { "id": "XP_017214532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214532" } ] } ], "protein_names": [ { "name": "Protocadherin alpha-3-like", "type": "synonym", "evidence": [ { "id": "A0A8M6Z2N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2/entry#names_and_taxonomy" } ] }, { "name": "protocadherin alpha-3-like", "type": "synonym", "evidence": [ { "id": "XP_017214532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214532" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017214532.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214532" } ] }, { "annotation": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2#function" }, { "database": "UniProtKB", "id": "ARBA00003436", "url": "https://www.uniprot.org/uniprotkb/ARBA00003436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108192084", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z2N2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z2N2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": 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Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108192084", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108192084", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z2N2", "url": "https://www.orthodb.org/?gene=A0A8M6Z2N2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017214532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214532", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2N2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAGGQRRRRENCWIALCIYFLIIGQQVSAQIRYSVPEEVKEGTVVGNIAKDLGLEVSSLVDRQFRVVSGSKEELFQINQDNGVLYVHKKIDRESLCVGSGVCMVNLKTVIENPLEIHYVEVDISDINDHSPRFPEKEQHLRISENTLPGADYQLQAARDPDYGTNSVRSYKLSPNDHFEIRVRENDEDKKPFLVLKKAVDREITTIYKLLLTAVDGGNPPKSGTLNITITILDINDNRPVFSRDTYSATLQENSLIGTVVVRVIATDMDEGMNSNIEYSFTTLHSKEHDVFELDPVTGEIRVKGAVDFEDTEVYKLDIQASDKGHPSMSANSRVVIKIIDVNDNSPEIEITSLSKNIPEDSKPGTVISLISVTDKDAGINGKVICQLNKNVPFELKPSFKDNMYSLVTKDRLDRETHSQYDITITASDLGQPSLTASTTLSVQISDVNDNAPEFSINPLDLYLMENNAAGSSIISVSASDKDSTENAVISYHIIRGDGSQADMSSYLNINSETGVVYSLKSFDFEMLKTSHFHVLATDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSEHSLFALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNVSLSATATVIVKVVEPKEAFAASDVKNAEKDEEENNVTFYLIITLGSVSVLFVISIIVLIVMQCSKSTDYSSKYLQDTNYDGTLCHSIQYRSGDKRYMLVGPRMSIGSTIAPGSNRNTLVIPDRRRRDSGEVSALSFVRSRSPLFA", "length": 800, "header": "tr|A0A8M6Z2N2-1|A0A8M6Z2N2_DANRE Isoform 1 of Protocadherin alpha-3-like OS=Danio rerio OX=7955 GN=LOC108192084 PE=4 SV=2 CANONICAL=A0A8M6Z2N2-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z2N2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2/entry#A0A8M6Z2N2-1", "sequence": { "sequence": "MEAGGQRRRRENCWIALCIYFLIIGQQVSAQIRYSVPEEVKEGTVVGNIAKDLGLEVSSLVDRQFRVVSGSKEELFQINQDNGVLYVHKKIDRESLCVGSGVCMVNLKTVIENPLEIHYVEVDISDINDHSPRFPEKEQHLRISENTLPGADYQLQAARDPDYGTNSVRSYKLSPNDHFEIRVRENDEDKKPFLVLKKAVDREITTIYKLLLTAVDGGNPPKSGTLNITITILDINDNRPVFSRDTYSATLQENSLIGTVVVRVIATDMDEGMNSNIEYSFTTLHSKEHDVFELDPVTGEIRVKGAVDFEDTEVYKLDIQASDKGHPSMSANSRVVIKIIDVNDNSPEIEITSLSKNIPEDSKPGTVISLISVTDKDAGINGKVICQLNKNVPFELKPSFKDNMYSLVTKDRLDRETHSQYDITITASDLGQPSLTASTTLSVQISDVNDNAPEFSINPLDLYLMENNAAGSSIISVSASDKDSTENAVISYHIIRGDGSQADMSSYLNINSETGVVYSLKSFDFEMLKTSHFHVLATDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSEHSLFALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNVSLSATATVIVKVVEPKEAFAASDVKNAEKDEEENNVTFYLIITLGSVSVLFVISIIVLIVMQCSKSTDYSSKYLQDTNYDGTLCHSIQYRSGDKRYMLVGPRMSIGSTIAPGSNRNTLVIPDRRRRDSGEVSALSFVRSRSPLFA", "length": 800, "header": "tr|A0A8M6Z2N2-1|A0A8M6Z2N2_DANRE Isoform 1 of Protocadherin alpha-3-like OS=Danio rerio OX=7955 GN=LOC108192084 PE=4 SV=2 CANONICAL=A0A8M6Z2N2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108192084", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108192084", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2N2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z2N2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2N2" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 134, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 227, "end_pos": 229 }, { "start_pos": 548, "end_pos": 550 }, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 654, "end_pos": 656 }, { "start_pos": 690, "end_pos": 692 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z2R4-1", "uniprot_ac": "A0A8M6Z2R4", "uniprot_id": "A0A8M6Z2R4_DANRE", "mass": { "chemical_mass": 178664.0, "monoisotopic_mass": 178664.0 }, "refseq": { "ac": "NP_001430324", "name": "NACHT and WD repeat domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430324" }, "gene_names": [ { "name": "LOC108179119", "type": "recommended", "evidence": [ { "id": "A0A8M6Z2R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2R4" } ] }, { "name": "LOC108179119", "type": "synonym", "evidence": [ { "id": "NP_001430324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430324" } ] } ], "protein_names": [ { "name": "NACHT and WD repeat domain-containing protein 2-like", "type": "synonym", "evidence": [ { "id": "NP_001430324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430324" }, { "id": "A0A8M6Z2R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2R4/entry#names_and_taxonomy" } ] }, { "name": "NACHT and WD repeat domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001430324", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430324" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01020673.1, GDQH01024372.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN08196787 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On Sep 12, 2025 this sequence version replaced XP_017207540.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001430324", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430324" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2R4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108179119", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2R4", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z2R4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z2R4", "database": "AlphaFoldDB", "categories": [] }, { "id": "108179119", "url": "https://www.ncbi.nlm.nih.gov/gene/108179119", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108179119", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179119", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z2R4", "url": "https://www.orthodb.org/?gene=A0A8M6Z2R4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19871", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19871", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19871:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19871:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001430324", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430324", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2R4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MACVQVYLCSNPEDSVVERTLIRQKVFPRLREYCRSTYGLDFRVIDPYEATKPKNWPTQQERLRILEDCWNNSLHSFFVGLVGEQYGDACLPEQVEASEFQLILQVCQRMGFKTDVLEKCYRRDENTIPPSFCMLEPSRRCKQTSVQQENPTEEKNWCKVFPEVRRILHDVVNQCIQEGTLALEKAQKYFQSSLENDLRYAYEGRSSEDVARCICYVHKITVPMKENTIPPEKEDQLHRLSQLRDQFLPSLVASHKAVVYCTTTKCNRLQCYTPEMRLDFGVGLCEQLNVDLKRLIDHTMLNKRTVAVDNFGEKDLCRIFSSLYRIERKEVEHVKSYLEGKNTLFPFILNGGPYSGKTVLLAHCASQVSVWLKNLDPEILVFFIDVNSSLRQLLKYICERADSSNTNINSIFQLKENFKRLLTVRSTSKNPLVIIIDGLDQLPKTDGQPDLTCLPKALAPNVKLLISVSANRHALLAALKQYYPDSALFCELQQVDTKSCNQLLTTLLQGSNRKITSGQQVYVNEALKKCTVPLYVELLYRQAVCWHSEFEITEETLDLEVHNSIVLIFDHMERKHGKSLVSKALSYLTLARYGMTTAELTDVLSCDDEVVESFLPQGEGVPATLRVPEVSVETLLSDLKGFLVQRNILGTQTLSWVNRHFPLVVCKQYLCSEETCLKIHHVLSDYFSGSWANGTKKHFIINKDTQIQSSSDVPRNIYIDRQVPSQPCIFSQPFYISTAMRTPTRPNLRKLHTLSFHLLKSGRIEELGSQMISQEYLQVMLHAMLADELFLWLEKTSQLIFPRELQLLHAILKSSACLLRNNPADLPIVLQAKLLPFLSVFPSLEECVNPARAEGLSLKCGMSTVLPSVPSVPYSQSTPQDSMASQIILSAGSLCGAVVVVLDNGAAWVCHGATCEGFKVTQSSNLKFTSVCSSGNTFLLSTCCGKLVLWDAVVKTQPLEIKIQHTENHKNKILEGVLVLGDNLFVWWREQNIVNVFVDKEELTQLCCTYEITCVLCSGEGNIIYCGQNEGSVTIFDWPNGQLLATLTCPKGMPLIEIILTEGDEVISCVDQAGNVFAWDLEMITEPVLICENHCGIQGKVLNTDYKGDSILLICKKQQIQLIDISQTDVLDQFNPPRGKTFKQAIIDQNSHFILALLCNCSFLLVWNCASGQCVLSLDTGNCQDINLLKCGTTYLAAIASVGVLIWDMDLIRTSALAPKSGKRVKIIITVGSQGGTCYSADGSKLVWKWAVSSGKVEGRFLHRGSVESMCISGDGNYLVSIADGDVYVWETCNGENTYRISGSQAYKVLITPKGNFGVALSENSSSRVWKLQSGHSICSIHLHLRNANISPEGTFLLGVNSGNLLAASLWSGNVNKCFSCSDQSDVVAFHSLLNHPDFVIVALSSGALYSWKLTEDTTCHQIQLPDSLFCQPEIFGLSSNGGYAVLSISECTINILNFSNSKLCSLRTEGPVLQTTVGVSGQYMVYACYSSLVCRNLSCDLHEKPMLVAIRLTDGGTIGRFYLCKMPSVLTLSKDLIVYVGFEDGSVGVYAVHDTKVGTSSWKAENLTLLNPLDEQLIWSPLLKPNLTWTELPLEFI", "length": 1598, "header": "tr|A0A8M6Z2R4-1|A0A8M6Z2R4_DANRE Isoform 1 of NACHT and WD repeat domain-containing protein 2-like OS=Danio rerio OX=7955 GN=LOC108179119 PE=4 SV=3 CANONICAL=A0A8M6Z2R4-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z2R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2R4/entry#A0A8M6Z2R4-1", "sequence": { "sequence": "MACVQVYLCSNPEDSVVERTLIRQKVFPRLREYCRSTYGLDFRVIDPYEATKPKNWPTQQERLRILEDCWNNSLHSFFVGLVGEQYGDACLPEQVEASEFQLILQVCQRMGFKTDVLEKCYRRDENTIPPSFCMLEPSRRCKQTSVQQENPTEEKNWCKVFPEVRRILHDVVNQCIQEGTLALEKAQKYFQSSLENDLRYAYEGRSSEDVARCICYVHKITVPMKENTIPPEKEDQLHRLSQLRDQFLPSLVASHKAVVYCTTTKCNRLQCYTPEMRLDFGVGLCEQLNVDLKRLIDHTMLNKRTVAVDNFGEKDLCRIFSSLYRIERKEVEHVKSYLEGKNTLFPFILNGGPYSGKTVLLAHCASQVSVWLKNLDPEILVFFIDVNSSLRQLLKYICERADSSNTNINSIFQLKENFKRLLTVRSTSKNPLVIIIDGLDQLPKTDGQPDLTCLPKALAPNVKLLISVSANRHALLAALKQYYPDSALFCELQQVDTKSCNQLLTTLLQGSNRKITSGQQVYVNEALKKCTVPLYVELLYRQAVCWHSEFEITEETLDLEVHNSIVLIFDHMERKHGKSLVSKALSYLTLARYGMTTAELTDVLSCDDEVVESFLPQGEGVPATLRVPEVSVETLLSDLKGFLVQRNILGTQTLSWVNRHFPLVVCKQYLCSEETCLKIHHVLSDYFSGSWANGTKKHFIINKDTQIQSSSDVPRNIYIDRQVPSQPCIFSQPFYISTAMRTPTRPNLRKLHTLSFHLLKSGRIEELGSQMISQEYLQVMLHAMLADELFLWLEKTSQLIFPRELQLLHAILKSSACLLRNNPADLPIVLQAKLLPFLSVFPSLEECVNPARAEGLSLKCGMSTVLPSVPSVPYSQSTPQDSMASQIILSAGSLCGAVVVVLDNGAAWVCHGATCEGFKVTQSSNLKFTSVCSSGNTFLLSTCCGKLVLWDAVVKTQPLEIKIQHTENHKNKILEGVLVLGDNLFVWWREQNIVNVFVDKEELTQLCCTYEITCVLCSGEGNIIYCGQNEGSVTIFDWPNGQLLATLTCPKGMPLIEIILTEGDEVISCVDQAGNVFAWDLEMITEPVLICENHCGIQGKVLNTDYKGDSILLICKKQQIQLIDISQTDVLDQFNPPRGKTFKQAIIDQNSHFILALLCNCSFLLVWNCASGQCVLSLDTGNCQDINLLKCGTTYLAAIASVGVLIWDMDLIRTSALAPKSGKRVKIIITVGSQGGTCYSADGSKLVWKWAVSSGKVEGRFLHRGSVESMCISGDGNYLVSIADGDVYVWETCNGENTYRISGSQAYKVLITPKGNFGVALSENSSSRVWKLQSGHSICSIHLHLRNANISPEGTFLLGVNSGNLLAASLWSGNVNKCFSCSDQSDVVAFHSLLNHPDFVIVALSSGALYSWKLTEDTTCHQIQLPDSLFCQPEIFGLSSNGGYAVLSISECTINILNFSNSKLCSLRTEGPVLQTTVGVSGQYMVYACYSSLVCRNLSCDLHEKPMLVAIRLTDGGTIGRFYLCKMPSVLTLSKDLIVYVGFEDGSVGVYAVHDTKVGTSSWKAENLTLLNPLDEQLIWSPLLKPNLTWTELPLEFI", "length": 1598, "header": "tr|A0A8M6Z2R4-1|A0A8M6Z2R4_DANRE Isoform 1 of NACHT and WD repeat domain-containing protein 2-like OS=Danio rerio OX=7955 GN=LOC108179119 PE=4 SV=3 CANONICAL=A0A8M6Z2R4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108179119", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179119", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1160, "end_pos": 1162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1324, "end_pos": 1326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1349, "end_pos": 1351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1458, "end_pos": 1460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1497, "end_pos": 1499, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1567, "end_pos": 1569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1587, "end_pos": 1589, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z2R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2R4" }, { "id": "PF05729", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 348, "end_pos": 474, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z2R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2R4" }, { "id": "PF25469", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25469" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NWD1/2-like winged helix-turn-helix", "eco_id": "ECO_0000259", "start_pos": 559, "end_pos": 639, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1160, "end_pos": 1162 }, { "start_pos": 1324, "end_pos": 1326 }, { "start_pos": 1349, "end_pos": 1351 }, { "start_pos": 1458, "end_pos": 1460 }, { "start_pos": 1497, "end_pos": 1499 }, { "start_pos": 1567, "end_pos": 1569 }, { "start_pos": 1587, "end_pos": 1589 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 693, "end_pos": 695 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z2T9-1", "uniprot_ac": "A0A8M6Z2T9", "uniprot_id": "A0A8M6Z2T9_DANRE", "mass": { "chemical_mass": 93327.0, "monoisotopic_mass": 93327.0 }, "refseq": { "ac": "XP_017207610", "name": "ras GTPase-activating protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207610" }, "gene_names": [ { "name": "rasa2", "type": "recommended", "evidence": [ { "id": "A0A8M6Z2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9" } ] }, { "name": "rasa2", "type": "synonym", "evidence": [ { "id": "XP_017207610", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207610" } ] } ], "protein_names": [ { "name": "Ras GTPase-activating protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9/entry#names_and_taxonomy" } ] }, { "name": "ras GTPase-activating protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017207610", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207610" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017207610.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017207610", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207610" } ] } ], "disease": [ { "disease_id": "DOID:3490", "recommended_name": { "id": "DOID:3490", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3490", "name": "Noonan syndrome", "description": "A RASopathy that is characterized by mildly unusual facial features, short stature, heart defects, bleeding problems, skeletal malformations, and many other signs and symptoms." }, "synonyms": [ { "id": "DOID:3490", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3490", "name": "Turner's phenotype, karyotype normal", "description": "" }, { "id": "MONDO:0008104", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008104", "name": "Noonan syndrome 1", "description": "Noonan syndrome caused by mutations in the PTPN11 gene." }, { "id": "MONDO:0008104", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008104", "name": "NS1", "description": "" }, { "id": "MONDO:0008104", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008104", "name": "Noonan syndrome 1", "description": "" }, { "id": "MONDO:0008104", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008104", "name": "Noonan syndrome type 1", "description": "" }, { "id": "MIM:163950", "resource": "MIM", "url": "https://www.omim.org/entry/163950", "name": "Noonan syndrome 1", "description": "Noonan syndrome 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "3490", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3490" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rasa2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-5660", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5660", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z2T9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z2T9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04010", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04010", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13370", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13370", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100331895", "url": "https://www.ncbi.nlm.nih.gov/gene/100331895", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001562", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001562", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100331895", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331895", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z2T9", "url": "https://www.orthodb.org/?gene=A0A8M6Z2T9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10194", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10194", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10194:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10194:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00616", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00616", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017207610", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207610", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HVZ2", "url": "https://www.uniprot.org/uniprotkb/A0AC58HVZ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HVZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HVZ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-5660", "url": "https://zfin.org/ZDB-GENE-030131-5660", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAEDDDTKIRILQSLRGKICEAKHLGPNSGPNRLRDLCTFCTISLDQEEVYRTKVFEKSVSPFYSEDFYFEIPRPFQCLSFYVYAKSMFQIRDLPVGKVAIRKEDLYKYCGKENWFQLQPVDPHSEVQGKVHLEMKLNELITENGSVCQQLVVQIIACQGLPLISGQNCDPYATVTLVGPTRSDQKKTKVKKKTSDPQFDETFHFEVTRSSSYKGRSQFHVEEEDIEKLEIKVELWNNGNLAQDVFLGETRVSVKILRNDHVHRAWYLLQPKGNGTKSKPDDLGSLRLKVTYTEDNVLPSACYTALRNLMLKSPDVKPISASAAHVLGDICREGVGYDALLPVVRLLLHHNRLLPFLTAVAALELENTQEANTIFRGNSLATRCIDDMMKIVGRSYLTVTLKPVLNEIFESIKTCEIDPVKLKEGDNVEVNKENLQGYVQKVFTSITQSSSSCPPLMCDVFRSLRQLASKRFPADPHVQYSAVSSFIFLRFFAVAVLSPHTFQLRSHHPDPEISRTLTLISKTIQSLGSWGSLSKNKLSSFKETFMCDFFKLFQEDECIEKVKKFLDEISSNVSKESSGVEDSFVLKEGEIHKRAQGKKRIGKKNFKKRWLRVTNQELSYHKQKGKEALCVIPVKHILGIEKLEESAFNRKNMFQVIHSEKPLYVQASNCVETNSWIEVLSQVSRCNPGRLSTFHLSAYVGGSWLCCKEPNESAPGCKPCTATVLANIQLDIDCDRETERIFSFFSTYRSRLQKMEDVCAGMSVYLGQQEECSAFTIQDPKETFRTIKELGEVLDELQSHHDSKGALTDEPGTIENPIVGKTA", "length": 823, "header": "tr|A0A8M6Z2T9-1|A0A8M6Z2T9_DANRE Isoform 1 of Ras GTPase-activating protein 2 isoform X1 OS=Danio rerio OX=7955 GN=rasa2 PE=4 SV=2 CANONICAL=A0A8M6Z2T9-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z2T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9/entry#A0A8M6Z2T9-1", "sequence": { "sequence": "MAEDDDTKIRILQSLRGKICEAKHLGPNSGPNRLRDLCTFCTISLDQEEVYRTKVFEKSVSPFYSEDFYFEIPRPFQCLSFYVYAKSMFQIRDLPVGKVAIRKEDLYKYCGKENWFQLQPVDPHSEVQGKVHLEMKLNELITENGSVCQQLVVQIIACQGLPLISGQNCDPYATVTLVGPTRSDQKKTKVKKKTSDPQFDETFHFEVTRSSSYKGRSQFHVEEEDIEKLEIKVELWNNGNLAQDVFLGETRVSVKILRNDHVHRAWYLLQPKGNGTKSKPDDLGSLRLKVTYTEDNVLPSACYTALRNLMLKSPDVKPISASAAHVLGDICREGVGYDALLPVVRLLLHHNRLLPFLTAVAALELENTQEANTIFRGNSLATRCIDDMMKIVGRSYLTVTLKPVLNEIFESIKTCEIDPVKLKEGDNVEVNKENLQGYVQKVFTSITQSSSSCPPLMCDVFRSLRQLASKRFPADPHVQYSAVSSFIFLRFFAVAVLSPHTFQLRSHHPDPEISRTLTLISKTIQSLGSWGSLSKNKLSSFKETFMCDFFKLFQEDECIEKVKKFLDEISSNVSKESSGVEDSFVLKEGEIHKRAQGKKRIGKKNFKKRWLRVTNQELSYHKQKGKEALCVIPVKHILGIEKLEESAFNRKNMFQVIHSEKPLYVQASNCVETNSWIEVLSQVSRCNPGRLSTFHLSAYVGGSWLCCKEPNESAPGCKPCTATVLANIQLDIDCDRETERIFSFFSTYRSRLQKMEDVCAGMSVYLGQQEECSAFTIQDPKETFRTIKELGEVLDELQSHHDSKGALTDEPGTIENPIVGKTA", "length": 823, "header": "tr|A0A8M6Z2T9-1|A0A8M6Z2T9_DANRE Isoform 1 of Ras GTPase-activating protein 2 isoform X1 OS=Danio rerio OX=7955 GN=rasa2 PE=4 SV=2 CANONICAL=A0A8M6Z2T9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HVZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9/entry#A0AC58HVZ2-1", "sequence": { "sequence": "MLKSPDVKPISASAAHVLGDICREGVGYDALLPVVRLLLHHNRLLPFLTAVAALELENTQEANTIFRGNSLATRCIDDMMKIVGRSYLTVTLKPVLNEIFESIKTCEIDPVKLKEGDNVEVNKENLQGYVQKVFTSITQSSSSCPPLMCDVFRSLRQLASKRFPADPHVQYSAVSSFIFLRFFAVAVLSPHTFQLRSHHPDPEISRTLTLISKTIQSLGSWGSLSKNKLSSFKETFMCDFFKLFQEDECIEKVKKFLDEISSNVSKESSGVEDSFVLKEGEIHKRAQGKKRIGKKNFKKRWLRVTNQELSYHKQKGKEALCVIPVKHILGIEKLEESAFNRKNMFQVIHSEKPLYVQASNCVETNSWIEVLSQVSRCNPGRLSTFHLSAYVGGSWLCCKEPNESAPGCKPCTATVLANIQLDIDCDRETERIFSFFSTYRSRLQKMEDVCAGMSVYLGQQEECSAFTIQDPKETFRTIKELGEVLDELQSHHDSKGALTDEPGTIENPIVGKTA", "length": 514, "header": "tr|A0AC58HVZ2-1|A0AC58HVZ2_DANRE Computationally mapped isoform of Ras GTPase-activating protein 2 isoform X2 OS=Danio rerio OX=7955 GN=rasa2 PE=4 SV=1 CANONICAL=A0A8M6Z2T9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 181, "start_aa": "Thr", "end_pos": 181, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr181", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100331895", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331895", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F916-1", "protein_name": "Ras GTPase-activating protein 2", "gene_name": "rasa3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVEEEGLRVFQSVKIKIGEAKNIPPYPGPNKMRDCYCTVNLDQEEVFRTKTIEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSSIGKVAVKKEDLQKYHGKDHWFPLQPVCADSEVQGKVHLELRLSELITDSGGLCHKLATRVLECQDLPIVNGQCDPYAAVSLLGPSRSEAKKTKVKRKNNNPQFDEIFFFEVTKPLSFTKRQFDVEEDDVDKLALKVDLWNASNLKFGDEFLGEVRVPLKVLGQAGVHDAWYFLQPRDNGHKSVKADELGSLRLNIVYTEDHVFPTEHYNPLRDLLLQSAHVQPVSASAAHILGEVCREKQEAAVPLVRLFLHYGKIVPFLSAIAHAEISRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLRVTLKPIIDEICSDHKPCEIDPVKLKESENLDTNRENLRQYVDRIFSVITSSGVSCPTVMCDIFFSLRESAASRFQVDADVRYTAVSSFIFLRFFAPAILSPNLFHLRPHHPDPCTSRTLTLISKTIQTLGSLAKSKSANFKESYMAAFYDYFNEQKYADAVKNFLDLISSSARWDQKSIETPIMLKEGFMIKRAQGRNRFGLKNFKKRWFRLTNHEFTYHKTKGEGALCSIPIENILAVERLEEESFKMKNMFQVIQPERALYIQANNCVEARDWIDILTKVSQCNRKRLSTFHPSAFLNGHWLCCKLSADTAPGCTPCTGGLPANIQLDVDGDRETERIYSLYSTYMSKLVKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTLRLVISAVQTLEQQHTQYKRDKFRKTKYGSQEHPIGDQSFQCYIRQQSESSTYSI", "length": 833 }, "evidence": [ { "id": "FB:FBgn0004390", "url": "https://alliancegenome.org/gene/FB:FBgn0004390#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P48423-1", "protein_name": "GTPase-activating protein", "gene_name": "RasGAP1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLLKKKRYMFDERDDNNINSPVAVEPSSNNNKMADTREVRIEEQLKVKIGEAKNLSSRNAANTSCSTQGTRDVYCTIALDQEEICRTPTIERTLTPFFGEEHQFKIPRRFRYLTIYLWDRDMKQDKPIGKIAIKREELHMYNHKDHWFSLRPVDQDSEVQGMVNVEVAFTEAQQTQSLSEGIDLGQHTLRHHQNLPHHSHQQRAHLNDYKENSELSNIQRASAAAASSSSAAMTLKTRAAGLFGHVHHPPSQTQHFPIINTTSTSSDQLSNWKSHGRFVGVTIKVPACVDLAKKQGTCDPFVVCTAHYSNKHQVTRRTKQRKKTVDPEFDEAMYFDLHIDADAGSTNTTGSNKSAGSLESSANKGYSIYPVGGADLVEIVVSVWHDAHGAMSDKVFLGEVRLPMLNKQEQQAVNPSAWYYLQPRSMTHSSRSLNATPRSCATPPGTRLSVDSTIGSLRLNLNYTADHVFPLATYDDLMNLLLESVDQRPITVSAVSILGELVSGKTEVAQPLVRLFTHTERIAPIIKALADHEISHLTDPTTIFRGNTLVSKMMDEAMRLSGLHYLHQTLRPVLSQIVAEKKPCEIDPSKIKDRSAVDTNLHNLQDYVERVFEAITKSADRCPKVLCQIFHDLRECAGEHFPSNREVRYSVVSGFIFLRFFAPAILGPKLFDLTTERLDAQTSRTLTLISKTIQSLGNLVSSRSSQQTCKEEFTVELYKKFCTEQHVDAVKHFLEVISTPSHASSSVHPAAAAATPLEPVLLKEGLMTKYPTSRKRFGRQFKQRHFRLTTHSLSYAKSKGKQPICDIPLQEIASVEQLKDKSFKMQNCFKIVHNDRSLIVQTTNCVEEREWFDLLHKICLMNSIRMQYFHPSAFVSGFYSCCGRSDENSPGCKKVLDKTMDYFQMDLVTALDPALDLQRIHTLIMSNMSVLESLLDPLTYHQSLSQTQHQQHNPLVPLATDLQKHSPQAFAEFKRTIEKLREKAYAIDRDHRDYKQGITRQLKYGSRQAPIGDDNYWHMMRAAGQLNQQHHQQQQHQQQQQQQQQQQLQQFQPQPVLPQMQNVRAYPYQPATSNMNAYCLHNMQYQQQRLPFHQQQQQHHQQLQQQQSQFQPLRSHQLQRHNNNLNNNNCGNGSSSSPSSTTSSVVAAPPSTTSSSQPAPPIY", "length": 1163 }, "evidence": [ { "id": "HGNC:9872", "url": "https://alliancegenome.org/gene/HGNC:9872#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5660", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5660#orthology", "database": "AGR" }, { "id": "MGI:2149960", "url": "https://alliancegenome.org/gene/MGI:2149960#orthology", "database": "AGR" }, { "id": "RGD:3538", "url": "https://alliancegenome.org/gene/RGD:3538#orthology", "database": "AGR" }, { "id": "FB:FBgn0004390", "url": "https://alliancegenome.org/gene/FB:FBgn0004390#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P58069-1", "protein_name": "Ras GTPase-activating protein 2", "gene_name": "Rasa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAPAAAASPEAPAVSGSADPETGDEDSREVRVLQSLRGRIYEAKNLLPYLGPNKMRDCFCTINLDQEEVYRTQVVEKSLSPYFSEEFYFEIPRTFQYLSFYVYDKNVLQRDLRIGKVAIKKEDLCSHSGKETWFSLQPIDSNSEVQGKVHLELRLNELITENGTVCQQLVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEVFYFEVTRSSSYSRKSQFQVEEEDIEKLEIRIDLWNNENLVQDVFLGEIKVPVNVLRSDSFHQAWYLLQPRDNGNKSSKTDDLGSLLLTLCYTEDCVLPSEYYGPLKTLLLKSPDVQPVSASAAYILGEICQDQKDAVLPLVRLLLHHNKLVPFITAVAELDLKDTPDANAIFRGNSLATQCLTEMMKIVGGHYLKVTLKPVLDEICESSKSCEIDPVKLKEGDNVENNKENLYYYVDKVFNTIVGSSVSCPTVMCDIFYSLRQMAAKKFPNHPHVQYSAVSSFVFLRFFAVAILSPHAFHLRPHYPDTQTVRTLTLISKTIQIIGNWGCQSRKKSRFKKSVMCEFLKMFQEERYFTDVKKFLDEISSTETKESSGTSEPVHLKEGEMYKRAQGRTRIGKKNFKKRWFCLTSRELTYHRQQGKDAIYTIPVKNILAVEKLEEGSFNKKNMFQVIHTEKTLYIQANNCVEANEWIDVLCRVSRCNHNRLSSFHPSAYLNGNWLCCQETSESTPGCKPCTAGIPADIQIDIDEDRETERIYSIFTLSLLKLQKMEETCGSIAVYQGPQKEPGYSKFTIEDSVATFKTIQQIKSTIEKLDEPHEKYRKKRSSSAKYGSKENPIVGKIS", "length": 847 }, "evidence": [ { "id": "HGNC:9872", "url": "https://alliancegenome.org/gene/HGNC:9872#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5660", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5660#orthology", "database": "AGR" }, { "id": "MGI:2149960", "url": "https://alliancegenome.org/gene/MGI:2149960#orthology", "database": "AGR" }, { "id": "RGD:3538", "url": "https://alliancegenome.org/gene/RGD:3538#orthology", "database": "AGR" }, { "id": "FB:FBgn0004390", "url": "https://alliancegenome.org/gene/FB:FBgn0004390#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14644-1", "protein_name": "Ras GTPase-activating protein 3", "gene_name": "RASA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVEDEGLRVFQSVKIKIGEAKNLPSYPGPSKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQKYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLATRIVECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKRKTNNPQFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRIPLKVLRQSSSYEAWYFLQPRDNGSKSLKPDDLGSLRLNVVYTEDHVFSSDYYSPLRDLLLKSADVEPVSASAAHILGEVCREKQEAAVPLVRLFLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLASKCIDETMKLAGMHYLHVTLKPAIEEICQSHKPCEIDPVKLKDGENLENNMENLRQYVDRVFHAITESGVSCPTVMCDIFFSLREAAAKRFQDDPDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTVQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSVEQPIVLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYHKSKGDQPLYSIPIENILAVEKLEEESFKMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVYHPSAYLSGHWLCCRAPSDSAPGCSPCTGGLPANIQLDIDGDRETERIYSLFNLYMSKLEKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTLKQVIAGVGALEQEHAQYKRDKFKKTKYGSQEHPIGDKSFQNYIRQQSETSTHSI", "length": 834 }, "evidence": [ { "id": "FB:FBgn0004390", "url": "https://alliancegenome.org/gene/FB:FBgn0004390#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q15283-1", "protein_name": "Ras GTPase-activating protein 2", "gene_name": "RASA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAPAAAAASSEAPAASATAEPEAGDQDSREVRVLQSLRGKICEAKNLLPYLGPHKMRDCFCTINLDQEEVYRTQVVEKSLSPFFSEEFYFEIPRTFQYLSFYVYDKNVLQRDLRIGKVAIKKEDLCNHSGKETWFSLQPVDSNSEVQGKVHLELKLNELITENGTVCQQLVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEIFYFEVTRSSSYTRKSQFQVEEEDIEKLEIRIDLWNNGNLVQDVFLGEIKVPVNVLRTDSSHQAWYLLQPRDNGNKSSKTDDLGSLRLNICYTEDYVLPSEYYGPLKTLLLKSPDVQPISASAAYILSEICRDKNDAVLPLVRLLLHHDKLVPFATAVAELDLKDTQDANTIFRGNSLATRCLDEMMKIVGGHYLKVTLKPILDEICDSSKSCEIDPIKLKEGDNVENNKENLRYYVDKLFNTIVKSSMSCPTVMCDIFYSLRQMATQRFPNDPHVQYSAVSSFVFLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTLISKTIQTLGSWGSLSKSKSSFKETFMCEFFKMFQEEGYIIAVKKFLDEISSTETKESSGTSEPVHLKEGEMYKRAQGRTRIGKKNFKKRWFCLTSRELTYHKQPGSKDAIYTIPVKNILAVEKLEESSFNKKNMFQVIHTEKPLYVQANNCVEANEWIDVLCRVSRCNQNRLSFYHPSVYLNGNWLCCQETGENTLGCKPCTAGVPADIQIDIDEDRETERIYSLFTLSLLKLQKMEEACGTIAVYQGPQKEPDDYSNFVIEDSVTTFKTIQQIKSIIEKLDEPHEKYRKKRSSSAKYGSKENPIVGKAS", "length": 850 }, "evidence": [ { "id": "HGNC:9872", "url": "https://alliancegenome.org/gene/HGNC:9872#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5660", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5660#orthology", "database": "AGR" }, { "id": "MGI:2149960", "url": "https://alliancegenome.org/gene/MGI:2149960#orthology", "database": "AGR" }, { "id": "RGD:3538", "url": "https://alliancegenome.org/gene/RGD:3538#orthology", "database": "AGR" }, { "id": "FB:FBgn0004390", "url": "https://alliancegenome.org/gene/FB:FBgn0004390#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60790-1", "protein_name": "Ras GTPase-activating protein 3", "gene_name": "Rasa3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVEEEGLRVFQSVRIKIGEAKNLPSYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQRYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLAARIFECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKKKTNNPQFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRLPLKILRHSSSYEAWYFLQPRDNGNKSLKPDDLGSLRLNVVYTEDHVFSSEYYSPLRDLLLKSADVEPVSASAAHILGEVCRDKQEAAIPLVRLLLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLHVTLKPTIEEICQSHKSCEIDPVKLKDGENLENNMESLRQYVDRIFTVITKSGVSCPTVMCDIFFSLREAAAKRFQDDLDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTIQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDQPLCNIPIENILAVERLEEESFRMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVFHPSAYLNGHWLCCRASSDTAAGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMGKLEKMQEACGSKSVYDGPEQEEYSTFVIDDPQETYKTLKQVIAGVGTLEQEHAQYRRDKFKKTRYGSQEHPIGDKSFQNYIRQQSEISTHSI", "length": 834 }, "evidence": [ { "id": "FB:FBgn0004390", "url": "https://alliancegenome.org/gene/FB:FBgn0004390#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63713-1", "protein_name": "Ras GTPase-activating protein 2", "gene_name": "Rasa2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAAPAAAALTEAPAVPGTAEPETGDEDSREVRVLQSLRGRIYEAKNLLPYLGPNKMRDCFCTINLDQEEVYRTQVVEKSLSPYFSEEFYFEIPRTFQYLSFYVYDKNVLQRDLRIGKVAIKKEDLCSHSGKETWFSLQPIDSNSEVQGKVHLELKLNELITENGTVCQQLVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEVFYFEVTRSSSYTRKSQFQVEEEDIEKLEIRIDLWNNENLVQDVFLGEIKVPVNVLRNDSSHQAWYLLQPRDNGNKSSKPDDLGSLLLTLCYTEDYVLPSEYYGPLKALLLKSPDVQPVSASAAYILGEICRDQKDAVLPLVRLLLHHNKLVPFITAVADLDLKDTQDANAIFRGNSLATQCLTEMMKIVGGHYLKVTLKPVLDEICESSKSCEIDPVKLKEGDNVESNKENLYYYVDKVFSAIVGSSVSCPTVMCDIFYSLRQMAAKRFPNNPHVQYSAVSSFVFLRFFAVAILSPHAFHLRPHYPDTQTVRTLTLISKTIQIIGNWGCQSRRKSRFKKSVMCEFLKMFQEERYFTDVKKFLDEISSTETKESSGTSEPVHLKEGEMYKRAQGRTRIGKKNFKKRWFCLTSKELTYHKQQGKDAIYTIPVKNILAVEKLEESSFNKKNMFQVIHTEKTLYIQANNCVEANEWIDMLCRVSRCNHNRLSSFHPSAYLNGNWLCCQETSEGTPGCKPCTAGIPADIQIDIDEDRETERIYSVFTLSLLKLQKMEEACGSIAVYQGPQKEPGYSKFTIEDSVATFKTIQQIKSTIEKLDEPHEKYRKKRSSSAKYGSKENPIVGKIS", "length": 847 }, "evidence": [ { "id": "HGNC:9872", "url": "https://alliancegenome.org/gene/HGNC:9872#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5660", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5660#orthology", "database": "AGR" }, { "id": "MGI:2149960", "url": "https://alliancegenome.org/gene/MGI:2149960#orthology", "database": "AGR" }, { "id": "RGD:3538", "url": "https://alliancegenome.org/gene/RGD:3538#orthology", "database": "AGR" }, { "id": "FB:FBgn0004390", "url": "https://alliancegenome.org/gene/FB:FBgn0004390#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9QYJ2-1", "protein_name": "Ras GTPase-activating protein 3", "gene_name": "Rasa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVEEEGLRVFQSVRIKIGEAKNLPSYPGPNKMRDCYCTVNLDQEEVFRTKIVEKSLCPFYGEDFYCEIPRSFRHLSFYIFDRDVFRRDSIIGKVAIQKEDLQRYHNRDTWFQLQHVDADSEVQGKVHLELRLSEVITDTGVVCHKLAARIFECQGLPIVNGQCDPYATVTLAGPFRSEAKKTKVKKKTNNPQFDEVFYFEVTRPCSYSKKSHFDFEEEDVDKLEIRVDLWNASNLKFGDEFLGELRIPLHVLRYASSYEAWYFLQPRDNGSKSVKPDDLGSLRLNVVYTEDHVFSSEYYSPLRDLLLKSADVEPVSASAAHILGEVCRDKQEAAIPLVRLLLHYGRVVPFISAIASAEVKRTQDPNTIFRGNSLTSKCIDETMKLAGMHYLHVTLKPTIEEICQSHKSCEIDPVKLKDGENLENNMESLRQYVDRIFSVITKSGVSCPTVMCDIFFSLREAAAKRFQDDLDVRYTAVSSFIFLRFFAPAILSPNLFQLTPHHTDPQTSRTLTLISKTIQTLGSLSKSKSASFKESYMATFYEFFNEQKYADAVKNFLDLISSSGRRDPKSIEQPILLKEGFMIKRAQGRKRFGMKNFKKRWFRLTNHEFTYQKSKGDQPLCNIPIENILAVERLEEESFRMKNMFQVIQPERALYIQANNCVEAKDWIDILTKVSQCNQKRLTVFHPSAYLNGHWLCCRASSDTAIGCTPCTGGLPANIQLDIDGDRETERIYSLFNLYMGKLEKMQEACGSKSVYDGPEQEEYSTFIIDDPQETYRTLKQVIAGVGTLEQEHAQYRRNKFKKTRYGSQEHPIGDKSFQNYIRQQSEISTHSI", "length": 834 }, "evidence": [ { "id": "FB:FBgn0004390", "url": "https://alliancegenome.org/gene/FB:FBgn0004390#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of Ras protein signal transduction", "id": "GO:0046580", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046580", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9" } ], "pmid": "" }, { "name": "phospholipid binding", "id": "GO:0005543", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005543", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z2T9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 711, "end_pos": 713, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 116, "start_aa": "Met", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z2T9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2T9" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", 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"start_pos": 711, "end_pos": 713 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z305-1", "uniprot_ac": "A0A8M6Z305", "uniprot_id": "A0A8M6Z305_DANRE", "mass": { "chemical_mass": 25547.0, "monoisotopic_mass": 25547.0 }, "refseq": { "ac": "XP_017213517", "name": "zinc finger matrin-type protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213517" }, "gene_names": [ { "name": "zmat4b", "type": "recommended", "evidence": [ { "id": "A0A8M6Z305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z305" } ] }, { "name": "zmat4b", "type": "synonym", "evidence": [ { "id": "XP_017213517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213517" } ] } ], "protein_names": [ { "name": "Zinc finger matrin-type protein 4", "type": "synonym", "evidence": [ { "id": "A0A8M6Z305", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z305/entry#names_and_taxonomy" } ] }, { "name": "zinc finger matrin-type protein 4", "type": "synonym", "evidence": [ { "id": "XP_017213517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213517" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017213517.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213517", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213517" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z305", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z305" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zmat4b", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z305", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z305", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z305", "database": "AlphaFoldDB", "categories": [] }, { "id": "100005974", "url": "https://www.ncbi.nlm.nih.gov/gene/100005974", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100005974", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005974", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR46144", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46144", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46144:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46144:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213517", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213517", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z305", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z305", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z305-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z305-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKSTEVDPGLFTDSYCKVCSAQLISESQRVAHYESRKHANKVRLYYMLHPVDGGCPAKKLRTDNGSADGDVDKNKCCTLCNMSFTSAVVAQSHYQGKIHAKRLRLLLGEPAAIMSKEVTVESDHMMDEDWKDGSPSTNGKLSQRYCQMCKAWFNNPGMARQHYNGKKHKKNGAQANLLAQLGKTLEDGEEMNGLKRSHTCEVCSVTLNSVAQYHAHLQGSKHQNNLKNK", "length": 229, "header": "tr|A0A8M6Z305-1|A0A8M6Z305_DANRE Isoform 1 of Zinc finger matrin-type protein 4 OS=Danio rerio OX=7955 GN=zmat4b PE=4 SV=2 CANONICAL=A0A8M6Z305-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z305-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z305/entry#A0A8M6Z305-1", "sequence": { "sequence": "MKSTEVDPGLFTDSYCKVCSAQLISESQRVAHYESRKHANKVRLYYMLHPVDGGCPAKKLRTDNGSADGDVDKNKCCTLCNMSFTSAVVAQSHYQGKIHAKRLRLLLGEPAAIMSKEVTVESDHMMDEDWKDGSPSTNGKLSQRYCQMCKAWFNNPGMARQHYNGKKHKKNGAQANLLAQLGKTLEDGEEMNGLKRSHTCEVCSVTLNSVAQYHAHLQGSKHQNNLKNK", "length": 229, "header": "tr|A0A8M6Z305-1|A0A8M6Z305_DANRE Isoform 1 of Zinc finger matrin-type protein 4 OS=Danio rerio OX=7955 GN=zmat4b PE=4 SV=2 CANONICAL=A0A8M6Z305-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100005974", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005974", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z305", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z305" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z305", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z305" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": 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"Protein" ] }, { "id": "A0A8M6Z335", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z335", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z335-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z335-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091116-36", "url": "https://zfin.org/ZDB-GENE-091116-36", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] }, { "id": "ZDB-GENE-091116-37", "url": "https://zfin.org/ZDB-GENE-091116-37", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAYETEHQETQYCFPNINSSCVKGRRYRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILFLAVNDLLIGLIVLPVEAIRLIERCWYFGETFCFLYLILIVLIFSASLSYLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNIAFVINNRNLNSSQKTDVCYGQCLIMMSFSWTIIDLSICFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGAKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTINVLMWNVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 335, "header": "tr|A0A8M6Z335-1|A0A8M6Z335_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=taar19r PE=3 SV=1 CANONICAL=A0A8M6Z335-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z335-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z335/entry#A0A8M6Z335-1", "sequence": { "sequence": "MAYETEHQETQYCFPNINSSCVKGRRYRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILFLAVNDLLIGLIVLPVEAIRLIERCWYFGETFCFLYLILIVLIFSASLSYLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNIAFVINNRNLNSSQKTDVCYGQCLIMMSFSWTIIDLSICFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGAKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTINVLMWNVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 335, "header": "tr|A0A8M6Z335-1|A0A8M6Z335_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=taar19r PE=3 SV=1 CANONICAL=A0A8M6Z335-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108191515", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191515", "resource": "KEGG Pathway" }, { "id": "dre:108191516", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191516", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NV51-1", "protein_name": "Trace amine associated receptor 19p", "gene_name": "taar19p", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEHQDTQYCFPNINSSCVKGKRSIQEYNIMYVLFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVTDLLIGLIVMPIQAIRLIETCWYFGDTLCGINLIIIGVIFSASFSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMCICLSWVYYSAYNTGLVINNGYFDTSHRTDVCYGDCSVIMSFSWLVTDLCLSFIFPCVIMITLYLRIFYVVHQQVKVINSLMKGGKCVTKGSVKRKSESKAALTLGIIVLVYLLCYIPYYICTLSVNSSTTITVLEWTVYTNSGLNPLVYALFYHWFKKTVKLILTLKIFHPESSLINVFTVHEL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z0V5-1", "protein_name": "Trace amine-associated receptor 13c", "gene_name": "taar19t", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDADTVYIKGQKGEQNKLLTGGDSLMAYETEDQETQYCFPDINSSCVKEKRSIQEYNIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLILMPVEAIRLIETCWYFGETFCVLYLILIGLIFSATLSCLVLIAVDRYVAVCHPLLYPQKITITNMLMSICLSWVCYSAYNTAFAFNNGYLNSSHRRDVCYGQCFIMMTFSWTVTDLSMCFIFPCVIMITLYSRIFYVVHQQVKVINSLMKGGKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTITVLMWTVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 361 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z0W1-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19h", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDYETEDQETQYCFPDINSSCVKYQRSSHEYNIMYVFFYFLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLVGLIVMPIQAIRLIETCWYFGDTFCGISLILSGVIISASLTNLVLIAVDRYVAVCHPLLYPQKITITNMLLIICLSWIYYSGYNTVLIIYNGYFETSERTDACDGDCLVMIRFSWIVTDLFISFIFPCVIIITLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVKRKSESKAALTLGIIVSVYLLSWIPYCICSVTVNSSTLITILSWTVYTNSGLNPLVYAIFYPWFKKTVKVILTLKIFDPASSLVNIFMEHDL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1I0-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKGRHSSHGYIIIYLFVSLLSVWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLIIGLFVIPIQAIKLIETCWYFGDTFCGLYLFLIFELLSASLSNLVLIAVDRYVAVCHPLLYPQKITITKTLMSICLSWVCYSAYNTALIINNRYSETSHRTDECYGRCFIVMSFSWLVADLVMSFIFPCLIMITLYLMIFYVVHQQVKVMNSLMKGGKCVTEGSVKRKSESKAALTLGIIVTIYLLCYIPYYICSLVVNSSTAIHVMSWTVYVNSGMNPLVYALFYPWFKKTAKIIFTLKIFQPASSLINIFTELDM", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z339-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "si:ch211-139n6.11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKGKRSRHEYIIMYVFFLLLSAWTVILNLLVIISISHFKKLHSPTNLLILSLSVADLLVGLIVIPIEAIKQIETCWYFGATFCGINLIIIGVIFSASFSNLVLIAVDRYVAVCHPLLYPQKITTAKMLMSICLSWLYYSAYNAGLVVNNGYFDTAHRTDVCYGDCTVIMSFGWIVIDLFMSFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKCLTEISVKRKSESKAALTLGIIVLVYLFSYIPYYICTLSVNSVTTNNVLGWTVYANSGLNPLVYALFYPWFKKTAKIILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z8I1-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19s", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKGRRYRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILFLAVNDLLIGLIVLPVEAIRLIERCWYFGETFCFLYLILIVLIFSASLSYLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNIAFVINNRNLNSSQKTDVCYGQCLIMMSFSWTVIDLSICFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTINVLMWNVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z8X3-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "si:ch211-238p8.31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKEKRSSHEYNIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVTDMFVGLIVIPVKAIKLIERCWYFGDTFCGLFIIIIGVIFSASLSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMSICLSWLYYSAYNTALIINNGYFDTSNRTDMCNGECPVMVSFSWILTDLSMCFIFPCLIMITLYSRIFFAVHQQVKVINSLMKRDKCVMKGSVKRKSERKAALTLGIIVTIYLLCYIPYYICSLVIISSTALNVLTWTMYANSGLNPLVYALFYPWFKKTAKLILTLKIFQPASSLVNIFTENEL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QD04-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "Taar9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSDFSPEPPMELCYENVNGSCIKSSYAPWPRAILYGVLGLGALLAVFGNLLVIIAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVESCWYFGESYCKFHTCFDTSFCFASLFHLCCISIDRYIAVTDPLTYPTKFTVSVSGLCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKYQARKIEGTANQAQASSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSTTNLFSEEAGAG", "length": 348 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091116-36", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-36#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091116-37", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-37#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923Y6-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "Taar9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELCYENVNGSCIKSSYSPWPRAILYAVLGLGALLAVFGNLLVITAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVEGCWYFGDTYCKFHTCFDTSFCFASLFHLCCISIDRYVAVTDPLTYPTKFTISVSGVCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKQQARKIEGSANQPQASSESYKERVARRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSRTNLFSEEAGAG", "length": 338 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96RI9-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "TAAR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD", "length": 348 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091116-36", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-36#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091116-37", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-37#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z335", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z335" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z335", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z335" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "trace-amine receptor activity", "id": "GO:0001594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001594", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z335", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z335" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z335", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z335" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 300, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 18, "end_pos": 20 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z339-1", "uniprot_ac": "A0A8M6Z339", "uniprot_id": "A0A8M6Z339_DANRE", "mass": { "chemical_mass": 37979.0, "monoisotopic_mass": 37979.0 }, "refseq": { "ac": "XP_017213592", "name": "trace amine-associated receptor 13c-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213592" }, "gene_names": [ { "name": "si:ch211-139n6.11", "type": "recommended", "evidence": [ { "id": "A0A8M6Z339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z339" } ] }, { "name": "si:ch211-139n6.11", "type": "synonym", "evidence": [ { "id": "XP_017213592", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213592" } ] } ], "protein_names": [ { "name": "Trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "A0A8M6Z339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z339/entry#names_and_taxonomy" } ] }, { "name": "trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "XP_017213592", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213592" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017213592.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213592" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z339", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z339" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-139n6.11", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z339", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091116-33", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-33", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z339", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z339", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100003630", "url": "https://www.ncbi.nlm.nih.gov/gene/100003630", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100003630", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003630", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z339", "url": "https://www.orthodb.org/?gene=A0A8M6Z339", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249:SF381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249:SF381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213592", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z339", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z339", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z339-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z339-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091116-33", "url": "https://zfin.org/ZDB-GENE-091116-33", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKGKRSRHEYIIMYVFFLLLSAWTVILNLLVIISISHFKKLHSPTNLLILSLSVADLLVGLIVIPIEAIKQIETCWYFGATFCGINLIIIGVIFSASFSNLVLIAVDRYVAVCHPLLYPQKITTAKMLMSICLSWLYYSAYNAGLVVNNGYFDTAHRTDVCYGDCTVIMSFGWIVIDLFMSFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKCLTEISVKRKSESKAALTLGIIVLVYLFSYIPYYICTLSVNSVTTNNVLGWTVYANSGLNPLVYALFYPWFKKTAKIILTLKIFQPASSLINIFTENEL", "length": 335, "header": "tr|A0A8M6Z339-1|A0A8M6Z339_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=si:ch211-139n6.11 PE=3 SV=1 CANONICAL=A0A8M6Z339-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z339-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z339/entry#A0A8M6Z339-1", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKGKRSRHEYIIMYVFFLLLSAWTVILNLLVIISISHFKKLHSPTNLLILSLSVADLLVGLIVIPIEAIKQIETCWYFGATFCGINLIIIGVIFSASFSNLVLIAVDRYVAVCHPLLYPQKITTAKMLMSICLSWLYYSAYNAGLVVNNGYFDTAHRTDVCYGDCTVIMSFGWIVIDLFMSFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKCLTEISVKRKSESKAALTLGIIVLVYLFSYIPYYICTLSVNSVTTNNVLGWTVYANSGLNPLVYALFYPWFKKTAKIILTLKIFQPASSLINIFTENEL", "length": 335, "header": "tr|A0A8M6Z339-1|A0A8M6Z339_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=si:ch211-139n6.11 PE=3 SV=1 CANONICAL=A0A8M6Z339-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100003630", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003630", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NV51-1", "protein_name": "Trace amine associated receptor 19p", "gene_name": "taar19p", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEHQDTQYCFPNINSSCVKGKRSIQEYNIMYVLFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVTDLLIGLIVMPIQAIRLIETCWYFGDTLCGINLIIIGVIFSASFSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMCICLSWVYYSAYNTGLVINNGYFDTSHRTDVCYGDCSVIMSFSWLVTDLCLSFIFPCVIMITLYLRIFYVVHQQVKVINSLMKGGKCVTKGSVKRKSESKAALTLGIIVLVYLLCYIPYYICTLSVNSSTTITVLEWTVYTNSGLNPLVYALFYHWFKKTVKLILTLKIFHPESSLINVFTVHEL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z0V5-1", "protein_name": "Trace amine-associated receptor 13c", "gene_name": "taar19t", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDADTVYIKGQKGEQNKLLTGGDSLMAYETEDQETQYCFPDINSSCVKEKRSIQEYNIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLILMPVEAIRLIETCWYFGETFCVLYLILIGLIFSATLSCLVLIAVDRYVAVCHPLLYPQKITITNMLMSICLSWVCYSAYNTAFAFNNGYLNSSHRRDVCYGQCFIMMTFSWTVTDLSMCFIFPCVIMITLYSRIFYVVHQQVKVINSLMKGGKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTITVLMWTVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 361 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z0W1-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19h", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDYETEDQETQYCFPDINSSCVKYQRSSHEYNIMYVFFYFLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLVGLIVMPIQAIRLIETCWYFGDTFCGISLILSGVIISASLTNLVLIAVDRYVAVCHPLLYPQKITITNMLLIICLSWIYYSGYNTVLIIYNGYFETSERTDACDGDCLVMIRFSWIVTDLFISFIFPCVIIITLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVKRKSESKAALTLGIIVSVYLLSWIPYCICSVTVNSSTLITILSWTVYTNSGLNPLVYAIFYPWFKKTVKVILTLKIFDPASSLVNIFMEHDL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1I0-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKGRHSSHGYIIIYLFVSLLSVWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLIIGLFVIPIQAIKLIETCWYFGDTFCGLYLFLIFELLSASLSNLVLIAVDRYVAVCHPLLYPQKITITKTLMSICLSWVCYSAYNTALIINNRYSETSHRTDECYGRCFIVMSFSWLVADLVMSFIFPCLIMITLYLMIFYVVHQQVKVMNSLMKGGKCVTEGSVKRKSESKAALTLGIIVTIYLLCYIPYYICSLVVNSSTAIHVMSWTVYVNSGMNPLVYALFYPWFKKTAKIIFTLKIFQPASSLINIFTELDM", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z335-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19r", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEHQETQYCFPNINSSCVKGRRYRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILFLAVNDLLIGLIVLPVEAIRLIERCWYFGETFCFLYLILIVLIFSASLSYLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNIAFVINNRNLNSSQKTDVCYGQCLIMMSFSWTIIDLSICFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGAKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTINVLMWNVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z8I1-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19s", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKGRRYRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILFLAVNDLLIGLIVLPVEAIRLIERCWYFGETFCFLYLILIVLIFSASLSYLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNIAFVINNRNLNSSQKTDVCYGQCLIMMSFSWTVIDLSICFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTINVLMWNVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z8X3-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "si:ch211-238p8.31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKEKRSSHEYNIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVTDMFVGLIVIPVKAIKLIERCWYFGDTFCGLFIIIIGVIFSASLSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMSICLSWLYYSAYNTALIINNGYFDTSNRTDMCNGECPVMVSFSWILTDLSMCFIFPCLIMITLYSRIFFAVHQQVKVINSLMKRDKCVMKGSVKRKSERKAALTLGIIVTIYLLCYIPYYICSLVIISSTALNVLTWTMYANSGLNPLVYALFYPWFKKTAKLILTLKIFQPASSLVNIFTENEL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCQ8-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKEQHSTNGYIIYLFVSFLSAWTVFLNLLVIISISHFKKLHTPTNMIVLSLAVADLLIGLIVMPVEAVKLIETCWYFGDTFCGFTLILIGVIPSASLGNLVLIAVDRYAAVCHPLLYPQKITMANMLMSICLSWVYYSTYITTLVIYNRYFDTSHRTDECYGQCLVMMSFSWILTDLFVCFVFPCVLIITLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVKRKSESKAALTLGIIVSVYLLCWIPYYICTLTVNSSTVLSVLTWVLYANSGLNPLVYALFYPWFKKTVKHILTMTICQLASSLVNIFTEHEL", "length": 334 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QD04-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "Taar9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSDFSPEPPMELCYENVNGSCIKSSYAPWPRAILYGVLGLGALLAVFGNLLVIIAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVESCWYFGESYCKFHTCFDTSFCFASLFHLCCISIDRYIAVTDPLTYPTKFTVSVSGLCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKYQARKIEGTANQAQASSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSTTNLFSEEAGAG", "length": 348 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091116-33", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-33#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5QD16-1", "protein_name": "Trace amine-associated receptor 3", "gene_name": "Taar3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLIYIPEDLSSCPKFGNKSCPPTNRSFRVRMIMYLFMTGAMVITIFGNLVIIISISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSMVRSVESCWYFGDSFCKFHASFDMMLSLTSIFHLCSIAIDRFYAVCDPLHYTTTMTVSMIKRLLAFCWAAPALFSFGLVLSEANVSGMQSYEILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSRRHARALSDMPANTKGAVGKNLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPIIVLDLLVWLGYFNSTCNPLIHGFFYPWFRKALQFIVSGKIFRSNSDTANLFPEAH", "length": 343 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5QD24-1", "protein_name": "Trace amine-associated receptor 3", "gene_name": "Taar3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLIYIPEDLSSCPKFGNKSCPPTNRSFRVRLIMYLLMTGAMVITIFGNLVIIISISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSMVRSVESCWYFGDSFCKFHASFDMMLSLTSIFHLCSIAIDRFYAVCAPLHYTTTMTASMIKRLLFFCWAAPALFSFGLVLSEANVSGMQSYEILIACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSRRHARALGNMPENTKGAGRNLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPIIVLDLLVWLGYFNSTCNPLIHGFFYPWFRKALEHIVSGKIFRSNSDTANLFPEAH", "length": 342 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091116-33", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-33#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q923Y6-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "Taar9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELCYENVNGSCIKSSYSPWPRAILYAVLGLGALLAVFGNLLVITAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVEGCWYFGDTYCKFHTCFDTSFCFASLFHLCCISIDRYVAVTDPLTYPTKFTISVSGVCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKQQARKIEGSANQPQASSESYKERVARRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSRTNLFSEEAGAG", "length": 338 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96RI9-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "TAAR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD", "length": 348 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091116-33", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-33#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9P1P4-1", "protein_name": "Putative trace amine-associated receptor 3", "gene_name": "TAAR3P", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLTYIPEDLSSCPKFVNKILSSHQPLFSCPGDNVFGYDWSHDYPLFGNLVIMVSISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSIMRSVESCWYFGDGFCKFHTSFDMMLRLTSIFHLCSIAIDRFYAVCYPLHYTTKMTNSTIKQLLAFCWSVPALFSFGLVLSEADVSGMQSYKILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSKQHARVISHVPENTKGAVKKHLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPILILDLLVWLRYFNSTCNPLIHGFFNPWFQKAFKYIVSGKIFSSHSETANLFPEAH", "length": 343 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z339", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z339" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z339", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z339" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "trace-amine receptor activity", "id": "GO:0001594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001594", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z339", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z339" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z339" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 300, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z340-1", "uniprot_ac": "A0A8M6Z340", "uniprot_id": "A0A8M6Z340_DANRE", "mass": { "chemical_mass": 33258.0, "monoisotopic_mass": 33258.0 }, "refseq": { "ac": "XP_017207814", "name": "uncharacterized protein si:ch211-133n4.7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207814" }, "gene_names": [ { "name": "si:ch211-133n4.7", "type": "recommended", "evidence": [ { "id": "A0A8M6Z340", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z340" } ] }, { "name": "si:ch211-133n4.7", "type": "synonym", "evidence": [ { "id": "XP_017207814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207814" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch211-133n4.7", "type": "synonym", "evidence": [ { "id": "A0A8M6Z340", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z340/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch211-133n4.7", "type": "synonym", "evidence": [ { "id": "XP_017207814", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207814" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017207814.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017207814", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207814" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z340", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z340" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-133n4.7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z340", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-665", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-665", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z340", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z340", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03590", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03590", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101885926", "url": "https://www.ncbi.nlm.nih.gov/gene/101885926", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885926", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885926", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z340", "url": "https://www.orthodb.org/?gene=A0A8M6Z340", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22803", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22803", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017207814", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207814", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z340", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z340", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z340-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z340-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-665", "url": "https://zfin.org/ZDB-GENE-060503-665", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDSVYENSRIVLSTVASNENSRNEGNHSYEQESEREVNTAKWNKLLLTVFAVSLVFALGGLCVVSILYVRALTQQSAQTNTKIMKRQLEELTANCSRVKDDLYIKDSMMKDLTANYSRVKDDLHIKDSMVKELTANNSRIKEQQSFYKAFRASNMTAFQGKLYFFSSDKLTWSSSRAFCVSRGTDLVTITSRSEQAFLQSKMNEWTWIGLSDLETEGRWVWVNNQTLNDTGVEFWYKRQSGKSEPDNWTKDDPSGEHCAIVKYALNYLKSWFDVSCEHTYKFICEKKI", "length": 288, "header": "tr|A0A8M6Z340-1|A0A8M6Z340_DANRE Isoform 1 of Uncharacterized protein si:ch211-133n4.7 OS=Danio rerio OX=7955 GN=si:ch211-133n4.7 PE=4 SV=2 CANONICAL=A0A8M6Z340-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z340-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z340/entry#A0A8M6Z340-1", "sequence": { "sequence": "MDSVYENSRIVLSTVASNENSRNEGNHSYEQESEREVNTAKWNKLLLTVFAVSLVFALGGLCVVSILYVRALTQQSAQTNTKIMKRQLEELTANCSRVKDDLYIKDSMMKDLTANYSRVKDDLHIKDSMVKELTANNSRIKEQQSFYKAFRASNMTAFQGKLYFFSSDKLTWSSSRAFCVSRGTDLVTITSRSEQAFLQSKMNEWTWIGLSDLETEGRWVWVNNQTLNDTGVEFWYKRQSGKSEPDNWTKDDPSGEHCAIVKYALNYLKSWFDVSCEHTYKFICEKKI", "length": 288, "header": "tr|A0A8M6Z340-1|A0A8M6Z340_DANRE Isoform 1 of Uncharacterized protein si:ch211-133n4.7 OS=Danio rerio OX=7955 GN=si:ch211-133n4.7 PE=4 SV=2 CANONICAL=A0A8M6Z340-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885926", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885926", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1RLL2-1", "protein_name": "Uncharacterized protein dcsignlg", "gene_name": "dcsignlg", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAVYENVECRDIKNSTGPQSQNHNRDEENDRKRRRWKCVVLVIMGLICALLLLFITLQNISITAERDLFKTYKNTVEELNHTISSLQHDNTDLETDKQQLEDKYNSLSLKKQQLETKYNSLSLGKQQLENRVTSLSAELKEARSKSGWFFMSTEAMSWSESRQFCRDRGADLVIIKSEEKQRFISSLVKEDTWIGLSVTETGGNKWKWVDNSPLNQGFWAKGEPNNYQGAKEDCVEVRISQGTPNNWNDRRCSDSRKAVCEK", "length": 263 }, "evidence": [ { "id": "MGI:1859834", "url": "https://alliancegenome.org/gene/MGI:1859834#orthology", "database": "AGR" }, { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" }, { "id": "RGD:621062", "url": "https://alliancegenome.org/gene/RGD:621062#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TFP3-1", "protein_name": "Uncharacterized protein zmp:0000000937 isoform X1", "gene_name": "zmp:0000000937", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSGIEMAQPIYGNILVNYDPTPKMDRCSLRNETASDSGKKRSSRAAPVCLVLLCLLLLTAVIVLSVFIYTNNTNFAEERRQLITNIANITEDRDKLLTDIINLTKIKDKVLINITNLEEDRDELLNKITTFTKARNEILKKNANLLKDKDQLIKQLQVFGQEAYYQSSFYYLSSERKSWTESRRDCKDRGADLIIINNKQEQDFIMKITSNNEFWIGLTDSDKEGIWKWVDGSNLTSRFWASSGSITEPNGRKTENCAVTHLKKHPELIGWLDVACDGAYQWICEKNILPVTS", "length": 294 }, "evidence": [ { "id": "MGI:1859834", "url": "https://alliancegenome.org/gene/MGI:1859834#orthology", "database": "AGR" }, { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P10716-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "Clec4f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKEAELNRDVAKFCTDNQCVILQPQGLGPKSAAPMAPRTLRHVQAIVALVVVTVFFSLLALFVVVLQPWRQKQNEDHPVKAGLHGGNYSGSDNCSQFVRRAEMQEAIQSLRASGNSSSCHKEIQTLKYQMDNVSSQVQLLGGHLEEANADIQQAKDVLKGTGALASETQALRSSLEVASADIHSLRGDLEKANAMTSQTQGLLKSSTDNTSAELHVLGRGLEEAQSEIQALRGSLQSSNDLGSRTQNFLQHSMDNISAEIQAMRDGMQRAGEEMTSLKKDLETLTAQIQNANGHLEQTDTQIQGLKAQLKSTSSLNSQIEVVNGKLKDSSRELQTLRRDLSDVSALKSNVQMLQSNLQKAKAEVQSLKTGLEATKTLAAKIQGQQSDLEALQKAVAAHTQGQKTQNQVLQLIMQDWKYFNGKFYYFSRDKKSWHEAENFCVSQGAHLASVTSQEEQAFLVQITNAVDHWIGLTDQGTEGNWRWVDGTPFDYVQSRRFWRKGQPDNWRHGNGEREDCVHLQRMWNDMACGTAYNWVCKKSTDWSVARTDQS", "length": 550 }, "evidence": [ { "id": "MGI:1859834", "url": "https://alliancegenome.org/gene/MGI:1859834#orthology", "database": "AGR" }, { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" }, { "id": "RGD:621062", "url": "https://alliancegenome.org/gene/RGD:621062#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-665", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-665#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70194-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "Clec4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKEAELNRDMARYCTDNQCVSLQPQGLGPKSAALMAPRTLRHVQVILALMVVTVIFSLLALFVVASQPWRPEWNKEPPSLLLRGSNNSGHDNHSQFVRETEMQVAIQRLRDYEENSSSCHKEVQILKYQMDNVSSLVQLLGSHLEDVNADILQTKDVLKESGALALETQALRSSLEVASADIHSLRGDLEKANAMTSQTRGLLKSSTENTSAELHVLGRGLEEAQSEIQALRGSLQSANDLSSQTQGFLQHSMDNISAQIQTVRDGMERAGEKMNSLKKELETLTAQTQKANGHLEQTDAQIQGLKAELKSTSSLNSRIEVVNGQMKDASRELQTLRRDLSDVSALKSNVQMLQSNLQRAKTEMQTLKADLQATKALTAKIQGEQNRLGALQEAVAAQKQEQKTQNQVLQLIAQNWKYFNGNFYYFSRDKKPWREAEKFCTSQGAHLASVTSQEEQAFLVQTTSSGDHWIGLTDQGTEGIWRWVDGTPFNNAQSKGFWGKNQPDNWRHRNGEREDCVHVRQQWNDMACGSSYPWVCKKSTGWSAARVG", "length": 548 }, "evidence": [ { "id": "MGI:1859834", "url": "https://alliancegenome.org/gene/MGI:1859834#orthology", "database": "AGR" }, { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" }, { "id": "RGD:621062", "url": "https://alliancegenome.org/gene/RGD:621062#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-665", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-665#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q59DY5-1", "protein_name": "C-type lectin 37Db", "gene_name": "lectin-37Db", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMVKLLLLFLVCWSALPLESSPLGNRYNLEIGEKQYYISLAKTNWFEASNHCRQNGGFLLNLESREELELLSPHLHPAYSYWLSINDLGERGVYVSEATGLEAPFLNWSAGEPDNSSGYDRCVELWLSTTSFQMNDLPCYSSVAFICQLN", "length": 150 }, "evidence": [ { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q59DY6-1", "protein_name": "C-type lectin 37Da", "gene_name": "lectin-37Da", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKTLVQLFLVVAGFAPGFGYDKYTTHIQNGNPYNLTVDMTPFIKINESYYVFGQTKVNWYVAYENCRRLQSELVTFETAEEFDAIAAFLNARGDRSEHWTSGNDLGKTGTHYWFSNAQLVTIKRWAPKQPDNAGGREHCIHLGYIYGYSTEFQLNDRPCHNHASSLFKYICEAPKQETVSIVVWK", "length": 186 }, "evidence": [ { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8IRH8-1", "protein_name": "Triforce, isoform B", "gene_name": "tfc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIRPTLIVVLISLASVDSGHNSPVTTIPVAEPISQVPHGFQLGQNNHISSSSNISRSGGGNGRDKRGAQLDPSEIARQNQITQQIFANYLERRLFPNRTANQKIPTIADILPKPKPSPRPRPRGFAASDGGNFKRSGGGAQRNRLAAAASKRQSGYNRKRLREEQEEEEEADDQERDQQPLANQEDFDYDVQESLQSVESEQHDQYYGNIFHRDPSENEVDNDCPNCVDESQYTPNKWTMPLLKLGEKRYYLGIFFKANWFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLGHEHFWISGTDLADEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGKGLKWNDSPCSFETYFVCEVQPN", "length": 376 }, "evidence": [ { "id": "RGD:621062", "url": "https://alliancegenome.org/gene/RGD:621062#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8N1N0-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "CLEC4F", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVVQQQTRPVPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPFNAAQNKAPGSKGSCPLRKYIIVNSGMGACSFIDTPPCPWILSN", "length": 589 }, "evidence": [ { "id": "MGI:1859834", "url": "https://alliancegenome.org/gene/MGI:1859834#orthology", "database": "AGR" }, { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" }, { "id": "RGD:621062", "url": "https://alliancegenome.org/gene/RGD:621062#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-665", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-665#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VIX1-1", "protein_name": "Galactose-specific C-type lectin, isoform A", "gene_name": "Lectin-galC1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLKLTVLLITLLVIAKTGWTREKFSIQVNEGNTFGALVKAEPFTKINDGYYFFGTESLNWYEAYEKCRELNSELVTFETDQEFDAVTAFLTANGSRLTYWTSGNDLAKTGSHRWFTNAQRISSLRWARNQPDNAGQKEHCIHLGYIYKDSRKFELNDRPCSQDPNSLFKYICEAPEMETISIVVWK", "length": 186 }, "evidence": [ { "id": "MGI:1859834", "url": "https://alliancegenome.org/gene/MGI:1859834#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W3D8-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG12111", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYRTETLLLILTSVGIPSLAYLPDVNIFTNYRTEVYNGIPSEIDTTPFVRIGDNYYYIEPMNKVNWFQAAGACRMMNAHLASIEDKPEMEALIKYMKAKGFKNNDYFWISGNDLGTEGAFYWMSNGRPMTYAPWNGPKQMPDNYGGNENCVHMFATREMINDANCKIQMLYVCEATEPKTFKFTYIKW", "length": 188 }, "evidence": [ { "id": "HGNC:25357", "url": "https://alliancegenome.org/gene/HGNC:25357#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z340", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z340" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z340", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z340" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 158, "end_pos": 285, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 154, "end_pos": 156 }, { "start_pos": 224, "end_pos": 226 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 26, "end_pos": 28 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z3G0-1", "uniprot_ac": "A0A8M6Z3G0", "uniprot_id": "A0A8M6Z3G0_DANRE", "mass": { "chemical_mass": 86297.0, "monoisotopic_mass": 86297.0 }, "refseq": { "ac": "XP_017208153", "name": "exostosin-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208153" }, "gene_names": [ { "name": "LOC101885478", "type": "recommended", "evidence": [ { "id": "A0A8M6Z3G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" } ] }, { "name": "LOC101885478", "type": "synonym", "evidence": [ { "id": "XP_017208153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208153" } ] }, { "name": "LOC137490193", "type": "synonym", "evidence": [ { "id": "A0A8M6Z3G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" } ] }, { "name": "LOC141376641", "type": "synonym", "evidence": [ { "id": "A0A8M6Z3G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" } ] } ], "protein_names": [ { "name": "Exostosin-1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z3G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0/entry#names_and_taxonomy" } ] }, { "name": "exostosin-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017208153", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208153" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017208153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208153" } ] }, { "annotation": "Glycosyltransferase required for the biosynthesis of heparan-sulfate.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0#function" }, { "database": "UniProtKB", "id": "ARBA00057959", "url": "https://www.uniprot.org/uniprotkb/ARBA00057959#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101885478", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z3G0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z3G0", "database": "AlphaFoldDB", "categories": [] }, { "id": "101885478", "url": "https://www.ncbi.nlm.nih.gov/gene/101885478", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "137490193", "url": "https://www.ncbi.nlm.nih.gov/gene/137490193", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "141376641", "url": "https://www.ncbi.nlm.nih.gov/gene/141376641", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885478", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885478", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z3G0", "url": "https://www.orthodb.org/?gene=A0A8M6Z3G0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31025", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31025", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31025:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31025:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48261", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48261", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48261:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48261:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017208153", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208153", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16213", "url": "https://www.rhea-db.org/rhea/16213", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "20908", "url": "https://www.rhea-db.org/rhea/20908", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I7B8", "url": "https://www.uniprot.org/uniprotkb/A0AC58I7B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I7B8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I7B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I7D3", "url": "https://www.uniprot.org/uniprotkb/A0AC58I7D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I7D3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I7D3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQAKKRYLLVSVGACSLLLAYLCGLQIGEFHSQNRAALYGLSQVPSFPPRWPEWVDPPLQTYLGEAEQEEDGPLLLHQHTSPRERREIQKNIYKSRRCRMDTCFDFQRCERGFKIYVYPPQKGEVPSESYQKILAAIEESRFYTTDPNEACLFVLSIDTLDRDQLSAQYVHNVRARIQSLPLWYEGRNHLIFNLYSGTWPDYTEELGFDIGQAMLAKASTDMDNFRPHFDISIPLFSKDHPQKGGDKGFLNLNNVPPLRKYLLVFKGKRYLTGIGSETRNALYHIHNGDDIILLTTCKHGKDWEKHKDARCDRDNEEYTKFDYQELLHNSSFCLVPRGRRLGSFRFLEALQAACIPVLLSNGWELPFSEVIDWSKAAIIGDERLLLQVPSITRSVGSDRILALRQQTQFLWDAYFSSVTKIVLTTLEIVHDRIRTHMSRSRQMWNSLPGGLYALPEFSSDLSLFPFYYSTLGKSPPQEFTAIIQALTPLQSQQQPIFKLIHAVAKSKFCVQILVLWNCEKPPPPRNKWPSITTPFSIIEGKRKTMSGRFYPHQAIKTDAVLSLDEDSVLSTNEVDFAFIVWQSFPDRIVGYPARSHYWDSGKGRWGYTSKWTNEYSMVLTGAAFYHRYYHHLYTHYLPMSLLSMVDQLANCEDILINFLISAVTKLPPIKVTQKKQYKETMMQQGSKASRWADPDHFAQRQSCMNSFTSWFGFMPLLHSQLRLDPVLFKDQVSILRKKYRDIERL", "length": 745, "header": "tr|A0A8M6Z3G0-1|A0A8M6Z3G0_DANRE Isoform 1 of Exostosin-1 isoform X1 OS=Danio rerio OX=7955 GN=LOC101885478 PE=3 SV=1 CANONICAL=A0A8M6Z3G0-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z3G0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0/entry#A0A8M6Z3G0-1", "sequence": { "sequence": "MQAKKRYLLVSVGACSLLLAYLCGLQIGEFHSQNRAALYGLSQVPSFPPRWPEWVDPPLQTYLGEAEQEEDGPLLLHQHTSPRERREIQKNIYKSRRCRMDTCFDFQRCERGFKIYVYPPQKGEVPSESYQKILAAIEESRFYTTDPNEACLFVLSIDTLDRDQLSAQYVHNVRARIQSLPLWYEGRNHLIFNLYSGTWPDYTEELGFDIGQAMLAKASTDMDNFRPHFDISIPLFSKDHPQKGGDKGFLNLNNVPPLRKYLLVFKGKRYLTGIGSETRNALYHIHNGDDIILLTTCKHGKDWEKHKDARCDRDNEEYTKFDYQELLHNSSFCLVPRGRRLGSFRFLEALQAACIPVLLSNGWELPFSEVIDWSKAAIIGDERLLLQVPSITRSVGSDRILALRQQTQFLWDAYFSSVTKIVLTTLEIVHDRIRTHMSRSRQMWNSLPGGLYALPEFSSDLSLFPFYYSTLGKSPPQEFTAIIQALTPLQSQQQPIFKLIHAVAKSKFCVQILVLWNCEKPPPPRNKWPSITTPFSIIEGKRKTMSGRFYPHQAIKTDAVLSLDEDSVLSTNEVDFAFIVWQSFPDRIVGYPARSHYWDSGKGRWGYTSKWTNEYSMVLTGAAFYHRYYHHLYTHYLPMSLLSMVDQLANCEDILINFLISAVTKLPPIKVTQKKQYKETMMQQGSKASRWADPDHFAQRQSCMNSFTSWFGFMPLLHSQLRLDPVLFKDQVSILRKKYRDIERL", "length": 745, "header": "tr|A0A8M6Z3G0-1|A0A8M6Z3G0_DANRE Isoform 1 of Exostosin-1 isoform X1 OS=Danio rerio OX=7955 GN=LOC101885478 PE=3 SV=1 CANONICAL=A0A8M6Z3G0-1" }, "locus": {} }, { "isoform_ac": "A0AC58I7B8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0/entry#A0AC58I7B8-1", "sequence": { "sequence": "MAMEQKLTMRVIVSEGDIRKMTMNPRPYILEDLISWLKGTLQTNYNFTLQYQDPEFNNELCNLTDLSELPDKPTIKIIPIIELVPVPGGSELCSDTSSQADTEILSISLDRSSQWPEVFEIPKFQVDVEYRLRQGNLQYLRDATFLKVTKELKHDILEKLAETMYAFKAYPTKEDFETVAKALVQTHPCLKETGSPSGWNGWKNSLKFKMGNYRTKMRQLGRLDVTVNGGKRGSGTTNGDPPNTQIKKPKKGEINFLPDFPEGMNDQNMEVAREVLVNEMMKTKPMESLVKKEMDVTFAFRRKEIVNEKPAISQVVHRWPALFTENQVYYEFGRVVGKNLRENFLDALDHLSPSLMDLFKKKKGLTGQLLAELLCQTKTTEPTDVRCLCLRGLPVILGDDPSAFFKACFDTADNDMYKQTPVGLLFIGEEKLKLNPSKVGIILEGNVVMDDLANLPQAFCVLFGLIYALHLDYPRYVKNTFCFVQQVMFNLGKSELAPKIQTLKNQLAV", "length": 509, "header": "tr|A0AC58I7B8-1|A0AC58I7B8_DANRE Computationally mapped isoform of Sterile alpha motif domain-containing protein 3 isoform X3 OS=Danio rerio OX=7955 GN=LOC101885478 PE=4 SV=1 CANONICAL=A0A8M6Z3G0-1" }, "locus": {} }, { "isoform_ac": "A0AC58I7D3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0/entry#A0AC58I7D3-1", "sequence": { "sequence": "MERTGRNIRMQGVTETMKNTQSFLESFTVDKFCRFCVASSRDTQQQEMAMEQKLTMRVIVSEGDIRKMTMNPRPYILEDLISWLKGTLQTNYNFTLQYQDPEFNNELCNLTDLSELPDKPTIKIIPIIELVPVPGGSELCSDTSSQADTEILSISLDRSSQWPEVFEIPKFQVDVEYRLRQGNLQYLRDATFLKVTKELKHDILEKLAETMYAFKAYPTKEDFETVAKALVQTHPCLKETGSPSGWNGWKNSLKFKMGNYRTKMRQLGRLDVTVNGGKRGSGTTNGDPPNTQIKKPKKGEINFLPDFPEGMNDQNMEVAREVLVNEMMKTKPMESLVKKEMDVTFAFRRKEIVNEKPAISQVVHRWPALFTENQVYYEFGRVVGKNLRENFLDALDHLSPSLMDLFKKKKGLTGQLLAELLCQTKTTEPTDVRCLCLRGLPVILGDDPSAFFKACFDTADNDMYKQTPVGLLFIGEEKLKLNPSKVGIILEGNVVMDDLANLPQAFCVLFGLIYALHLDYPRYVKNTFCFVQQVMFNLGKSELAPKIQTLKNQLAV", "length": 556, "header": "tr|A0AC58I7D3-1|A0AC58I7D3_DANRE Computationally mapped isoform of Sterile alpha motif domain-containing protein 3 isoform X2 OS=Danio rerio OX=7955 GN=LOC101885478 PE=4 SV=1 CANONICAL=A0A8M6Z3G0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885478", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885478", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" } ], "pmid": "" }, { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" } ], "pmid": "" }, { "name": "glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity", "id": "GO:0050508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050508", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" } ], "pmid": "" }, { "name": "N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity", "id": "GO:0050509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050509", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" } ], "pmid": "" }, { "name": "heparan sulfate proteoglycan biosynthetic process", "id": "GO:0015012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015012", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3G0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16213", "name": "", "equation": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5IGR6-1", "Q5IGR7-1", "Q5IGR8-1", "A0AB32TX90-1" ], "evidence": [ { "id": "16213", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16213" } ] }, { "id": "20908", "name": "", "equation": "3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n+1)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5IGR6-1", "Q5IGR7-1", "Q5IGR8-1" ], "evidence": [ { "id": "20908", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/20908" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AB32TX90", "gene_name": "ext2", "activity": [ { "ec_number": "2.4.1.224", "activity": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "A0AB32TX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX90" } ] }, { "ec_number": "2.4.1.224", "activity": "", "evidence": [ { "id": "A0AB32TX90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX90" } ] } ] }, { "uniprot_ac": "Q5IGR6", "gene_name": "ext1c", "activity": [ { "ec_number": "2.4.1.224", "activity": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "Q5IGR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ] }, { "ec_number": "2.4.1.225", "activity": "3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n+1)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "Q5IGR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ] }, { "ec_number": "2.4.1.225", "activity": "", "evidence": [ { "id": "Q5IGR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ] }, { "ec_number": "2.4.1.224", "activity": "", "evidence": [ { "id": "Q5IGR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR6" } ] } ] }, { "uniprot_ac": "Q5IGR7", "gene_name": "ext1b", "activity": [ { "ec_number": "2.4.1.224", "activity": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "Q5IGR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ] }, { "ec_number": "2.4.1.225", "activity": "3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n+1)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "Q5IGR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ] }, { "ec_number": "2.4.1.225", "activity": "", "evidence": [ { "id": "Q5IGR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ] }, { "ec_number": "2.4.1.224", "activity": "", "evidence": [ { "id": "Q5IGR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR7" } ] } ] }, { "uniprot_ac": "Q5IGR8", "gene_name": "ext1a", "activity": [ { "ec_number": "2.4.1.224", "activity": "3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-N-acetyl-alpha-D-glucosamine = 3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "Q5IGR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ] }, { "ec_number": "2.4.1.225", "activity": "3-O-{alpha-D-GlcNAc-[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP-alpha-D-glucuronate = 3-O-{[(1->4)-beta-D-GlcA-(1->4)-alpha-D-GlcNAc](n+1)-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl}-L-seryl-[protein] + UDP + H(+).", "evidence": [ { "id": "Q5IGR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ] }, { "ec_number": "2.4.1.225", "activity": "", "evidence": [ { "id": "Q5IGR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ] }, { "ec_number": "2.4.1.224", "activity": "", "evidence": [ { "id": "Q5IGR8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5IGR8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z3G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" }, { "id": "PF03016", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exostosin GT47", "eco_id": "ECO_0000259", "start_pos": 110, "end_pos": 395, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z3G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3G0" }, { "id": "PF09258", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09258" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl transferase 64", "eco_id": "ECO_0000259", "start_pos": 479, "end_pos": 728, 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"https://www.uniprot.org/uniprotkb/A0A8M6Z3H2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3H2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050208-378", "url": "https://zfin.org/ZDB-GENE-050208-378", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTIIIMSVLLLVSLVPHLTFTAHVGIEDGTEAKPHSRPYMVSLQYYSQHICGGFLITEQFVLTAAHCWAKGLVLSVVAGAHYLSENEIYDSFEVESYIPHPDYNSNTFENDILLLKLKTKVRLSNIVGMISLPKDGEDVKADTLCSVAGWGTLWKNGPKTDRLMEAETVIVNDAECERRWGSLYKASKMICVYGHGGSCYGDSGGPLVCDNTAFGITSFVDLYLCNSRLRPNVYTRTSAHLPWIHNITGNF", "length": 251, "header": "tr|A0A8M6Z3H2-1|A0A8M6Z3H2_DANRE Isoform 1 of trypsin OS=Danio rerio OX=7955 GN=si:dkey-21e2.7 PE=4 SV=1 CANONICAL=A0A8M6Z3H2-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z3H2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3H2/entry#A0A8M6Z3H2-1", "sequence": { "sequence": "MTIIIMSVLLLVSLVPHLTFTAHVGIEDGTEAKPHSRPYMVSLQYYSQHICGGFLITEQFVLTAAHCWAKGLVLSVVAGAHYLSENEIYDSFEVESYIPHPDYNSNTFENDILLLKLKTKVRLSNIVGMISLPKDGEDVKADTLCSVAGWGTLWKNGPKTDRLMEAETVIVNDAECERRWGSLYKASKMICVYGHGGSCYGDSGGPLVCDNTAFGITSFVDLYLCNSRLRPNVYTRTSAHLPWIHNITGNF", "length": 251, "header": "tr|A0A8M6Z3H2-1|A0A8M6Z3H2_DANRE Isoform 1 of trypsin OS=Danio rerio OX=7955 GN=si:dkey-21e2.7 PE=4 SV=1 CANONICAL=A0A8M6Z3H2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "dre:100034650", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100034650", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4LG43-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG33225", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNNSVEFLIAYIYVNTYIFVAEIVLLASLVLGARLGSSTLLTNDCGTTRHPSRIRRVVGGNDADRFANPWMVMVLGENNVFCSGSLITRLFVLTSASCLLSLPKQVILGEYDRNCTSADCTSIRQVIDIDQKIIHGQFGLETVKKYDIALLRLAKKVSISDYVRPICLSVDRQVGRSVQHFTATGWGTTEWNEPSTILQTVTLSKINRKYCKGRLRQNIDASQLCVGGPRKDTCSGDAGGPLSLTLKIDGDGKWNNKSRAFLIGIVSYGSSSCSGIGVYTNVEHYMDWIVRTINKSNTEKIANVHRS", "length": 307 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8M1RP82-1", "protein_name": "trypsin", "gene_name": "si:dkey-78l4.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTIIIISLLLLVSLVPHPTFTAHVGIVDGQEAKPHSRPYMVSVQLFGQNICGGFLISDQFVLTAAQCWHQNQDLTVVVGAHDLRKRQNSKNFIVKSHITHPNFNSKTFENDIMLLKLKGKVPLNNKIRPISLPKNGESFKADTPCSVAGWGRLWTKGPVSDLLLEAKTAIVNDAECKLRWGSHYVPSMMICAFGHGGSCNGDGGGPLVCNNTAVGVTIFRDRYLCNSRLLPNVYTKISAYLPWIRSIIGNV", "length": 251 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RP83-1", "protein_name": "trypsin", "gene_name": "si:dkey-78l4.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTIIIISLLLLVSLVPDLTYTAHVGIEDGTKAKPHSRPYMVSLQKNSRHSCGGFLITEQFVLTAAHCWKKGDVITVGVGAHDLSGNEIYDTFEVTSYIPHPEYKLNSDRNDIMLLKLNKKVRLSYNVGLISLPKDGEDVEADILCSVAGWGRLWLKGPSPDRLREAETVIVNDAECERRWNKTYKASKMICAYGHGGSCSGDSGGPLVCNNTAVGITSFSDRYLCNSRLLPNVYTRISAYLPWIHNITGNVYKKK", "length": 255 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RTG9-1", "protein_name": "Duodenase-1", "gene_name": "si:dkey-78l4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAIIIISLLLLVSLVPDLTFTARVGIEDGTEAKPHSRPYMVSLQKNSWHTCGGFLITEQFVLTAAHCWKKGDVITVVVGAHDLSGNEIYDTFKVTSYMRYEDYKLNSDRNDIMLLKLNKKVRLSKNVGLISLPKKGEDVEADTLCSVAGWGILWRKGPESDRLREAETVIVNNAECERRWESLYKASKMICAYGHGGTCNGDSGGPLVCGNTAVGITSFGDRYLCNSRLLPDVYTRISAYLPWIHNITGNA", "length": 251 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" }, { "id": "FB:FBgn0030775", "url": "https://alliancegenome.org/gene/FB:FBgn0030775#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AXT9-1", "protein_name": "Granzyme-like protein 1", "gene_name": "si:dkey-78l4.8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTIIIISLLLLVSLVPHLTFTAHVRIVNGNRAKPHSRPYMVSIQKNSNHICGGFLITEQFVLTAAHCWEKNEKLTVVVGAHDLKKNETGSVRINVMSYHTPKQYKNTTLKNDIMLLKLEQKVKLSKNISLISIPQKKDKKVINAGTSCSVAGWGTKKTDGPTSNYLLEAKVEIMENKKCQKLWNKHGPNSDVQYSVSKMMCTHGLGGSCKGDSGGPLVCGNTAVGVTSFGNPDACNSPSLPNVYTKISAYLDWIKKIIRKFK", "length": 262 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YV09-1", "protein_name": "trypsin", "gene_name": "si:dkey-78l4.10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLITFFLLLLVSLLPHLTFMAHVGIVNGSVAKPHSRPYMVSVQLDGQHICGGFLITEEFVLTAAHCWNGEENLTVVVGAHDLRQSMASDRIEVESYIRHPSYNSKFIWNDIMVFKLKERVTQNSSVGWISISKKNEHVDANTLCSVAGWGLLTNGTLSDCLMEANVYIISNTECKSKWGRHFSVSQMMCTRGHGGSCRYDSGGPLVCGDTAVGITSFGDPHLCNSPKHPNVYTNISAYRPWIDSVIKNGKLDNIFNYYRAF", "length": 262 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PSZ8-1", "protein_name": "Granzyme-like protein 1", "gene_name": "si:dkey-21e2.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTITIISLLLLVSLVPDVTFTARVGIVDGTEAKPHSRPYMVSLQYDGEHICGGSLITEEFVLTAAHCWEEGDVLTVVVGAHDLSKNEIYNSYEVASYIPHQDYELNPDLNDIMLLKLKKKVRLSNSIGLISLPKDGEDVEADTICSVAGWGDLWSKGPVPDRLMEAETVIVNDAECERRWGSEYVASEMICAYGHGGSCNGDSGGPLVCNNTAVGITAFGDGYLCNSRLYPNAYTKISAYLQWIRFKLENV", "length": 251 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q575-1", "protein_name": "Granzyme-like protein 1", "gene_name": "si:dkey-21e2.13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPPNFSVFIQCLYSESSLIFFIMTIITISLLLLVSLVPHLTFTARVGIVDGTEAEPHSRPYMVSLQKKSRHICGGFLIHQQFVLTAAHCWKGDPLTVVVGAHDLRMTDSSNSFKVTSYVQHPNFDSNTFENDIMLLKLNKKVTLSNNVGLISLPKYGEDVKADTACSVAGWGRLSKKGPKPDRLREAETVIVNDAECERRWGQTYVASEMICVYGPGGTCKGDSGGPLVCGDTAVGITSFSDPYLCNSRVYPSIFTRISAYLSWIYHLTENV", "length": 273 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q7D5-1", "protein_name": "Duodenase-1", "gene_name": "si:dkey-21e2.10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTIISLLLLVSLVPHLTFTARVGIQDGTEAKPHSRPYMVSLQFYKLHMCGGSLITEEFVLTAAHCWEEDDVLTVVTGAHDLRKKAINNVYKVKSYIPHPDFNSKTLENDIMLLQLKTKVRLSNNVGLISLPKDGEDVKADTLCSVAGWGDLWSKGPETDRLREAETVIVNNAECERRWESDYVASKMICVYGHGGTCSGDSGGPLVCGDTVVGITSFGEPYLCNSRLFPDVHTRISAYLPWIHNITGKV", "length": 249 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A940-1", "protein_name": "Granzyme-like protein isoform 1 precursor", "gene_name": "si:dkey-78l4.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTIIIISLLLLVSLPPHLTFTVNGNEATPHSRPYMVSVQFNDIHFCGGFLISEEFALTAAHCRKNSAEKLTVVVGAHDLKNKEEGSVRIKVKSCYTHPHFVQKTLQNDIMLLKLERNVKLSQTVHLTSLPKQKEDTKAGTICSVFGWGRQYTNGPLSDRLLETEVKIMENMQCLKLWNKRDDIKVKYSISKMMCVYGHGGSCEGDSGGPLVCEDTVVGITSFGNPHLCNSRLFPNVYTKISAYHDWIWKIINKQK", "length": 255 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TKN4-1", "protein_name": "trypsin", "gene_name": "si:dkey-21e2.14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTIIIISLLLLVSLVPDLTFTARVGIEDGTEAKPHSRPYMVSLQKNSKNSCGGSLITEEFVLTAAHCWKKGDVITVVVGAHDLSENETYDSFEVTSYIPHPEFSWQNYENDIMLLKLNKKVTLSDNVGLISLPKNGEDVKEDAVCSVAGWGRLWLNGPRPDRLMEAETVIVSGEECKRRWESLFKPSKMFCVYGHGGTCKGDSGGPLVCGDHAVGVTSFSDRYSCNSRLLPNMYTKISAYLSWIQKITGKI", "length": 251 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O35205-1", "protein_name": "Granzyme K", "gene_name": "Gzmk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFSSWALVSLVAGVYMSSECFHTEIIGGREVQPHSRPFMASIQYRSKHICGGVLIHPQWVLTAAHCYSWFPRGHSPTVVLGAHSLSKNEPMKQTFEIKKFIPFSRLQSGSASHDIMLIKLRTAAELNKNVQLLHLGSKNYLRDGTKCQVTGWGTTKPDLLTASDTLREVTVTIISRKRCNSQSYYNHKPVITKDMICAGDARGQKDSCKGDSGGPLICKGIFHALVSQGYKCGIAKKPGIYTLLTKKYQTWIKSKLAPSRAH", "length": 263 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49863-1", "protein_name": "Granzyme K", "gene_name": "GZMK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKFSSFSLFFLIVGAYMTHVCFNMEIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHSLSKNEASKQTLEIKKFIPFSRVTSDPQSNDIMLVKLQTAAKLNKHVKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDSGGPLICKGVFHAIVSGGHECGVATKPGIYTLLTKKYQTWIKSNLVPPHTN", "length": 264 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49864-1", "protein_name": "Granzyme K", "gene_name": "Gzmk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFSSSALVFLVAGIYMSSESFHTEIIGGREVQPHSRPFMASIQYRGKHICGGVLIHPQWVLTAAHCYSRGHSPTVVLGAHSLSKNEPMKQTFEIKEFIPFSGFKSGTNDIMLIKLRTAAELNKHVQLLHLRSKNYIRDGTKCQVTGWGSTKPDVLTTSDTLQEVTVTIISRKRCNSQSYYNHKPVITKDMICAGDRRGEKDSCKGDSGGPLICKGVFHALVSGGYKCGISNKPGVYTLLTKKYQTWIKSKLAPSSAH", "length": 258 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050208-378", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-378#orthology", "database": "AGR" }, { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7KVM8-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG33226", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAHSLIEFKMKWLLVCFILALRSYESLGQDLLDPNCVQTPVGVREQILGGHNADIKLHPWMVQILQRGYHFCGGSLISSLFVLTAAHCHSRYRLKVRFGRYSGITPRYLCSSQYCSPFGPEIDVKRIFLHSSYRDYHNYDIALFLLAKPVRYNVQTRPICVLQTSNKDKLRQFLNYVAMFNVTGWGKTESQLTSTILQTTSLFHLDRKFCAQIFDRKIGWPHICAGHSQSSTCTGDSGGPLSAELTFSGVKRTVLFGIISYGAPNCREVTVFTNVLRYSNWIRDIVHNFTPS", "length": 292 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8IRK5-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG30289", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEVINAVIAALVCLFIANNNVMSRLLVENCGISKDDPYVPNIFGGAKTNIQENPWMVLVWSSKPCGGSLIARQFVLTAAHCVSFEDLYVRLGDYETLDPMPYCLNNHCIPKFYNISVDMKIVHENYNGITLQNDIALLRMSEAVEYSDYVRPICLLVGEQMQSIPMFTVTGWGETEYGQFSRILLNATLYNMDISYCNIKFNKQADRSQICAGSHTSNTCKGDSGGPLSSKFHYGNRLLSFQYGLVSYGSERCAANVAGVYTNVSYHREWIFNKMVQFKPTGHTTFWLSKLVGQTCNITDIIRNIELMYNRIVYEN", "length": 316 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8IRK6-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "Dmel\\CG30288", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLPIRQLVIVACLFIGIIRTESGRLLENDCGTTSSNGYRARIDGGRDAGMESNPWMVRVMISGKAVCGGSLITARFVLTAEHCISPMYMNVRLGEYDTRHPIFDCDDFVCTPRAYNVDVDRKIVHSNPGYDIGLLRMQRSVIFSNYVRPICLILGKTLGGNPLSILRFNFTGWGTNSDGEEQDRLQTATLQQLPQWSCERPGRPLDISYICAGSYISDSCKGDSGGPLSAIRTFEGQGRVFQFGVASQGLRLCSGLGIYTNVTHFTDWILDVIQNHSDDFE", "length": 282 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8MLV8-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "SPH37", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGAGAVQLLLLIALVFLKVQGQPHLLDPQCVTARSEPGLYRVINGKPADLFSNPWMVIIIERGMMKCGGSLITPRYVLTAAHCKSETKSQLTVRLGDYDVNQAVDCSSYGCIPRPREINVTRTYVPSHYTNFRKNDIALLRLETTVQYGDNIRSICLLMGDYTWSSNILKNLVKFNTTGWGRTESRINSPVLQQASLTHHHLSYCAQVFGKQLDKSHICVASSTGSTCQGDSGGPLTARVRIGSERRVILFGVVSYGAVHCFGPTVYTNVIHFANWIELHTKKN", "length": 284 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VXC7-1", "protein_name": "trypsin", "gene_name": "Dmel\\CG9673", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MADPRITLGLGLLIFGLILSAEASPQGRILGGEDVAQGEYPWSASVRYNKAHVCSGAIISTNHILTAAHCVSSVGITPVDASTLAVRLGTINQYAGGSIVNVKSVIIHPSYGNFLHDIAILELDETLVFSDRIQDIALPPTTDEETEDVDAELPNGTPVYVAGWGELSDGTASYKQQKANYNTLSRSLCEWEAGYGYESVVCLSRAEGEGICRGDAGAAVIDDDKVLRGLTSFNFGPCGSKYPDVATRVSYYLTWIEANTQ", "length": 261 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050208-378", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-378#orthology", "database": "AGR" }, { "id": "FB:FBgn0030775", "url": "https://alliancegenome.org/gene/FB:FBgn0030775#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2G1-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "SP37", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKNTKIFVVVVLLAASSVVVLGSESGSFLEHPCGTVPISQFKILGGHNAPVASAPWMAMVMGEGGFHCGGTLITNRFVLTSAHCIANGELKVRLGVLEREAEAQKFAVDAMFVHTDYYFDQHDLALLRLAKRVHYSDNISPICLLLDPLVKNIDEHIVKFRTYGWGKTESRSSSRMLQKTSLFNLHRSECAKQYPHQQINRNHICAESANANTCNGDSGGPLTAIVTYDHVQMVFQFGVTSFGHADCSKATVFTNVMTHLDWIVNTVRRAEIM", "length": 273 }, "evidence": [ { "id": "RGD:68401", "url": "https://alliancegenome.org/gene/RGD:68401#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3H2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3H2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3H2" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3H2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3H2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z3H2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3H2" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 249, "start_aa": "Ile", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.4.21.4", "ec_name": "Preferential cleavage: Arg-|-Xaa, Lys-|-Xaa.", "evidence": [ { "id": "3.4.21.4", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.4.21.4" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], 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This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017208180.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017208180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208180" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3I3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108180325", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I3", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z3I3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z3I3", "database": "AlphaFoldDB", "categories": [] }, { "id": "108180325", "url": "https://www.ncbi.nlm.nih.gov/gene/108180325", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:108180325", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108180325", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z3I3", "url": "https://www.orthodb.org/?gene=A0A8M6Z3I3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_017208180", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208180", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3I3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLGDGCLASDWIHITVNSFSCTTDSILLRMATPYSRPPPLHITCVKVHSSQKAVTFIKHENKIIVDTYKVTSLCALTDGDAVYLSIKNGSDPEFEEGHSYIVKNVTISNKYGRRCLFVNKGTIKFRTAPLAISEEAKRAAREALCPPSRPITGEEEDIFSETGYLSLRGQLEKVEVPRMTRTHIPILDLRMKCGSVVHDVSLWREEALNELYVGDIIELSHLKVNGRPDGRAKFDSSNHTTFKLIDRDIQEAVLEIVGVSEMHDKLILLDSHMDEYIVPVHFYAGTIEELANQLPLQLKLRHICGSVLHVEPASVKQVPPDVPCGGSAGVEQVPPDVPCGGSAGVDQVPPDVPSGGSASVDQVPPYVPSGGSADADQGPPDVHSGGSADPNQVHPEDTQDSMDCLF", "length": 407, "header": "tr|A0A8M6Z3I3-1|A0A8M6Z3I3_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108180325 PE=4 SV=2 CANONICAL=A0A8M6Z3I3-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z3I3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I3/entry#A0A8M6Z3I3-1", "sequence": { "sequence": "MSLGDGCLASDWIHITVNSFSCTTDSILLRMATPYSRPPPLHITCVKVHSSQKAVTFIKHENKIIVDTYKVTSLCALTDGDAVYLSIKNGSDPEFEEGHSYIVKNVTISNKYGRRCLFVNKGTIKFRTAPLAISEEAKRAAREALCPPSRPITGEEEDIFSETGYLSLRGQLEKVEVPRMTRTHIPILDLRMKCGSVVHDVSLWREEALNELYVGDIIELSHLKVNGRPDGRAKFDSSNHTTFKLIDRDIQEAVLEIVGVSEMHDKLILLDSHMDEYIVPVHFYAGTIEELANQLPLQLKLRHICGSVLHVEPASVKQVPPDVPCGGSAGVEQVPPDVPCGGSAGVDQVPPDVPSGGSASVDQVPPYVPSGGSADADQGPPDVHSGGSADPNQVHPEDTQDSMDCLF", "length": 407, "header": "tr|A0A8M6Z3I3-1|A0A8M6Z3I3_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108180325 PE=4 SV=2 CANONICAL=A0A8M6Z3I3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108180325", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108180325", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 239, "end_pos": 241 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z3I5-1", "uniprot_ac": "A0A8M6Z3I5", "uniprot_id": "A0A8M6Z3I5_DANRE", "mass": { "chemical_mass": 173536.0, "monoisotopic_mass": 173536.0 }, "refseq": { "ac": "XP_017208863", "name": "LOW QUALITY PROTEIN: uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208863" }, "gene_names": [ { "name": "LOC100148332", "type": "recommended", "evidence": [ { "id": "A0A8M6Z3I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5" } ] }, { "name": "LOC100148332", "type": "synonym", "evidence": [ { "id": "XP_017208863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208863" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017208863", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208863" }, { "id": "A0A8M6Z3I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 5% of CDS bases frameshifts :: corrected 1 indel internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017208863.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017208863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208863" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3I5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3I5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100148332", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z3I5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z3I5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100148332", "url": "https://www.ncbi.nlm.nih.gov/gene/100148332", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100148332", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148332", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z3I5", "url": "https://www.orthodb.org/?gene=A0A8M6Z3I5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017208863", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208863", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3I5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSALTRSFSVESSELSSAATSERQRQSLLKDSVKMSDPEPCRIKQEETEELIDVIVKEESEELSEDEEKHHVKTETKTEDKTEQSVSMEETVVKGFTCTQCGKRLSSKYNLKIHMRIHTGEKPYKCSLCEKRFNRSGNLRTHKRIHTGDKPYKCSHCDMRFNRPENLKTHLLLHTGEKTHTCDQCGKTFLRSSGLKNHLRLHTIEKLYPCSECGKSFRTQSSLRKHQKLHTAVKEFFCFECGKAFTRAKYLRQHQRVHTGEKPYKCSHCNKRFRLSGTLKHHKMIHTGEKPYTCTQCGKSFTQTSSLNEHKKIHIGEKKHKCDQCGKTFLRPSELRIHLRVHTNERLYSCSECGKSFSQQSHLKDHLKIHTGVREYVCFDCGKSFITNGGLKKHQMIHTGEKPYVCSHCNKTFRQSGLLKTHERTHTGEKPYTCTQCGQSFTRLANLNKHVLNHTRETNHKFKKHKRMYLPENSTLYSRTPDFSVKEPLLCIIKGNCLVLGSPTTGCSHAGVIPCSDWLLVYKACIKRSFRQESESSFLLRSVFGVELLGFPHPFGRRPTIITFFCGILNFPTLYLLVFTCFPFISIHLCFYSAFTRRSSSQLKLLQSSYVVKLYIDISATISERQRQSLLKMSNPEPCRIKQEETEELIDVKVKEESEELSEDEKKHHVKREEETQSETEDSISVERTAVKCFTCTQCGKSLTSKYDLNRHMRIHTGEKPFKCSHCDKRFNHLGNLNAHLLIHTGEKTHRCDQCGKTFLRPSELRSHLRVHTNERPYPCSECGKSFRNWSNLNTHQKIHTGVKEFVCSECKKTFTTSHLLKRHQRIHTGEKPYKCSHCDKRFRLTGTLKNHKMTHSGNKPHKCAQCDKTFLRPSELTNHFRLHTNERPYSCSECGKSFKLLSHLKSHQKIHTGVRDFVCSECGKTFIQAGDLRRHQRTHTGEKPYKCSHCDRTFRVSGHLKIHERDHTGEKPYTCTQCGKGFTQLSTLNKHVLIHTREKNHKXKTIKKTFLRPSELKKHLRVLSHLEFYTSARFLTILFIYLLVILLLLILRCSRLAVMTSALTRSFSVESSELSSAAISXRQRQGLLKDSEKMSDPEPCRIKQEETEEIIEVVVKEESEDLSEDEEKHHVQSESETQLEIENSFSVKTASRNGFTCTQCGKSFSQKCDLNRHMKIHTGEKTHKCDQCSKTFLRASGLKIHLRVHSNEKPYLCSECGKGFTQQSNLTAHQKIHTGVREFVCFKCEKGFITAHHLKQHMRIHTGEKPYKCSLCDKRFKRLQILKTHEMIHTGEKPYKCTQCGKSFRQFSNFNEHTQRHTGEKNHKCDQCSKTFLRPSELKIHLRFHTNEKLYSCSECGKCFTQQSSLNAHQKIHTGVREFVCFKCGKSFITAGDLRRHQLIHTEEKPYKCSHCDKTFRDSGYLKKHERIHTGEKPFTCTQCGMSFGQSSNLKKHALIHTGEKTHKLNKKKNNFEGCRAEETSESSYKGALTESYNFPT", "length": 1499, "header": "tr|A0A8M6Z3I5-1|A0A8M6Z3I5_DANRE Isoform 1 of LOW QUALITY PROTEIN: uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100148332 PE=3 SV=3 CANONICAL=A0A8M6Z3I5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z3I5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5/entry#A0A8M6Z3I5-1", "sequence": { "sequence": "MTSALTRSFSVESSELSSAATSERQRQSLLKDSVKMSDPEPCRIKQEETEELIDVIVKEESEELSEDEEKHHVKTETKTEDKTEQSVSMEETVVKGFTCTQCGKRLSSKYNLKIHMRIHTGEKPYKCSLCEKRFNRSGNLRTHKRIHTGDKPYKCSHCDMRFNRPENLKTHLLLHTGEKTHTCDQCGKTFLRSSGLKNHLRLHTIEKLYPCSECGKSFRTQSSLRKHQKLHTAVKEFFCFECGKAFTRAKYLRQHQRVHTGEKPYKCSHCNKRFRLSGTLKHHKMIHTGEKPYTCTQCGKSFTQTSSLNEHKKIHIGEKKHKCDQCGKTFLRPSELRIHLRVHTNERLYSCSECGKSFSQQSHLKDHLKIHTGVREYVCFDCGKSFITNGGLKKHQMIHTGEKPYVCSHCNKTFRQSGLLKTHERTHTGEKPYTCTQCGQSFTRLANLNKHVLNHTRETNHKFKKHKRMYLPENSTLYSRTPDFSVKEPLLCIIKGNCLVLGSPTTGCSHAGVIPCSDWLLVYKACIKRSFRQESESSFLLRSVFGVELLGFPHPFGRRPTIITFFCGILNFPTLYLLVFTCFPFISIHLCFYSAFTRRSSSQLKLLQSSYVVKLYIDISATISERQRQSLLKMSNPEPCRIKQEETEELIDVKVKEESEELSEDEKKHHVKREEETQSETEDSISVERTAVKCFTCTQCGKSLTSKYDLNRHMRIHTGEKPFKCSHCDKRFNHLGNLNAHLLIHTGEKTHRCDQCGKTFLRPSELRSHLRVHTNERPYPCSECGKSFRNWSNLNTHQKIHTGVKEFVCSECKKTFTTSHLLKRHQRIHTGEKPYKCSHCDKRFRLTGTLKNHKMTHSGNKPHKCAQCDKTFLRPSELTNHFRLHTNERPYSCSECGKSFKLLSHLKSHQKIHTGVRDFVCSECGKTFIQAGDLRRHQRTHTGEKPYKCSHCDRTFRVSGHLKIHERDHTGEKPYTCTQCGKGFTQLSTLNKHVLIHTREKNHKXKTIKKTFLRPSELKKHLRVLSHLEFYTSARFLTILFIYLLVILLLLILRCSRLAVMTSALTRSFSVESSELSSAAISXRQRQGLLKDSEKMSDPEPCRIKQEETEEIIEVVVKEESEDLSEDEEKHHVQSESETQLEIENSFSVKTASRNGFTCTQCGKSFSQKCDLNRHMKIHTGEKTHKCDQCSKTFLRASGLKIHLRVHSNEKPYLCSECGKGFTQQSNLTAHQKIHTGVREFVCFKCEKGFITAHHLKQHMRIHTGEKPYKCSLCDKRFKRLQILKTHEMIHTGEKPYKCTQCGKSFRQFSNFNEHTQRHTGEKNHKCDQCSKTFLRPSELKIHLRFHTNEKLYSCSECGKCFTQQSSLNAHQKIHTGVREFVCFKCGKSFITAGDLRRHQLIHTEEKPYKCSHCDKTFRDSGYLKKHERIHTGEKPFTCTQCGMSFGQSSNLKKHALIHTGEKTHKLNKKKNNFEGCRAEETSESSYKGALTESYNFPT", "length": 1499, "header": "tr|A0A8M6Z3I5-1|A0A8M6Z3I5_DANRE Isoform 1 of LOW QUALITY PROTEIN: uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100148332 PE=3 SV=3 CANONICAL=A0A8M6Z3I5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100148332", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148332", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3I5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3I5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3I5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3I5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3I5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3I5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1227, "end_pos": 1229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 790, "end_pos": 792, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z3I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3I5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 97, "end_pos": 124, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1227, "end_pos": 1229 }, { "start_pos": 135, "end_pos": 137 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 474, "end_pos": 476 }, { "start_pos": 790, "end_pos": 792 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z3N1-1", "uniprot_ac": "A0A8M6Z3N1", "uniprot_id": "A0A8M6Z3N1_DANRE", "mass": { "chemical_mass": 33543.0, "monoisotopic_mass": 33543.0 }, "refseq": { "ac": "XP_017214091", "name": "protein TBATA", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214091" }, "gene_names": [ { "name": "tbata", "type": "recommended", "evidence": [ { "id": "A0A8M6Z3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3N1" } ] }, { "name": "tbata", "type": "synonym", "evidence": [ { "id": "XP_017214091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214091" } ] } ], "protein_names": [ { "name": "Protein TBATA", "type": "synonym", "evidence": [ { "id": "A0A8M6Z3N1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3N1/entry#names_and_taxonomy" } ] }, { "name": "protein TBATA", "type": "synonym", "evidence": [ { "id": "XP_017214091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214091" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017214091.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214091" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3N1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3N1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tbata", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3N1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-121030-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121030-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z3N1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z3N1", "database": "AlphaFoldDB", "categories": [] }, { "id": "557892", "url": "https://www.ncbi.nlm.nih.gov/gene/557892", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:557892", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557892", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z3N1", "url": "https://www.orthodb.org/?gene=A0A8M6Z3N1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33772:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33772:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017214091", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214091", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3N1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3N1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3N1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-121030-4", "url": "https://zfin.org/ZDB-GENE-121030-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDESEQQANVSVSRADLSSVQRESAGSRATTRGSLRFGTLSHHSFFSRHNPHPHRVRHMQGLNGKPVCMVNDDWFAFTPLCPHPLIKSQVSVSGSRSSAFFTPEISSDRSGPRAALISESWREELKDLATKITLSAAAETQHDKREPQKHADDEAPRRKTQYSSQSGRIIPSSSWGGKKRSRTSHRRMTTHTHMLEGLELKVLELLCQILQTDSLSMVQQWLLLASDKEKELVQGLLKQAVSDCSSLSLHTSADPLNTEHLLLEPAGRAHRSSLRRSETLPEEPERIGEAEVLTLYPENT", "length": 300, "header": "tr|A0A8M6Z3N1-1|A0A8M6Z3N1_DANRE Isoform 1 of Protein TBATA OS=Danio rerio OX=7955 GN=tbata PE=4 SV=3 CANONICAL=A0A8M6Z3N1-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z3N1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3N1/entry#A0A8M6Z3N1-1", "sequence": { "sequence": "MDESEQQANVSVSRADLSSVQRESAGSRATTRGSLRFGTLSHHSFFSRHNPHPHRVRHMQGLNGKPVCMVNDDWFAFTPLCPHPLIKSQVSVSGSRSSAFFTPEISSDRSGPRAALISESWREELKDLATKITLSAAAETQHDKREPQKHADDEAPRRKTQYSSQSGRIIPSSSWGGKKRSRTSHRRMTTHTHMLEGLELKVLELLCQILQTDSLSMVQQWLLLASDKEKELVQGLLKQAVSDCSSLSLHTSADPLNTEHLLLEPAGRAHRSSLRRSETLPEEPERIGEAEVLTLYPENT", "length": 300, "header": "tr|A0A8M6Z3N1-1|A0A8M6Z3N1_DANRE Isoform 1 of Protein TBATA OS=Danio rerio OX=7955 GN=tbata PE=4 SV=3 CANONICAL=A0A8M6Z3N1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:557892", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557892", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K1J3-1", "protein_name": "Similar to human chromosome 4 open reading frame 17", "gene_name": "C2h4orf17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTERNKGCFIVRHTPHPRRVCHIQGLNNVPICTVKDDLPIRMLCCPRQLSPSQKNETTLAKVSNPPRSASPESLSIRGVSPAKNKVPERPHSEPFRKINHNFRTSRDNPLVNKKDEYKPKKPLVASRMCSGAASPSSDVMNTRINRNENTVCIPNYLDQEIKILLKLCDILHTDSLTEVLDWLLQASNKEKEWLSALIHSELSEINLLTRHRVNTPEPAAESRKSPTSVTPTTKLLQNSHAKLKALHESREEHQPLRMTSQGSEGNKMASKGAETPLFIRRNKKLPVTEYFNNPKSPFKPNTQESRSARPMSVRSVQGYSPQRALYPLTHGREK", "length": 334 }, "evidence": [ { "id": "RGD:1309170", "url": "https://alliancegenome.org/gene/RGD:1309170#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121030-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121030-4#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A5F8MPV9-1", "protein_name": "RIKEN cDNA 4930579F01 gene", "gene_name": "4930579F01Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESVGGCFIVRHTPHPRRVCHIQGLNNIPICTVNDDDTCPRSLYISDQFSPSERNETSVAKFTNPPSTASPESLRVGGLSPAPAKLPARPQSEPCRKSSQCFKTSKDNPLVKNKVEHKAKRPLPSARMCSAAAFQSSDAMSNRMDGNENTVHIPNYLDQEIKILAKLSEILHTDSLAEVLNWLLQASNKEKEWVSALVHSELAEINLLTRHRANTPTEPAAEPRKPYTSGTPTTKLLQNSRAKLKALTGSRERQLHRTSSQGSKGNKLVSHGAETPLFIRRNKKQTPVTEYLNPESPLGSNSVASRSPNPGSARSAQGYSPQRVFYP", "length": 327 }, "evidence": [ { "id": "RGD:1309170", "url": "https://alliancegenome.org/gene/RGD:1309170#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I5YC32-1", "protein_name": "Thymus, brain and testes associated", "gene_name": "Tbata", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQATQGAAQQRLPRNRGRRTWLSIFPAHLHSTKGPPSSQGQQEKEVQKATSPKTEPQPEKKPEQVPRSHGDVGFQKEPVVPGIVDFELIHEDLKTTKPPTLQPTPGAYRFGRLSHHSFFSRHHPQAQRVTHIQDIAGKPICMVRDEFSLAALTQPSFLTPCVMGMPTVSVPIGDPQSNRKPRLSTSATWRKNLKDLASRVTFFTKEIASTTNEQKDEPPMKDPSPREQGAKYSAETGRLIPAYSHALTRRNRQAQRGHTSGKGGGVQASILQDQELLGGLTAPGVKFSGPVGRGPRAGFLGLHLLPPVPPPPLHSYRQHRQPGLGSPPSTSKKQTEHILPLLDPRPQKKPPAKKAARDGDSQLLHWMEPLTKHLAETTQSGQQAANSESPTSWQTFPDSWSSRVGRPLGYPKSPPKTSQHAGLDPGASLSDSTNRFSKGYPVLAALRSAKRKRFGFGASADGLGSAHPPASPLHPSREAVAPTSRASRPSSRDTTGNLQSIPEEDENTTSIQDRQTRVHGQSPSPPSTSDREPRGENDQAQGLKLRSIAESTETSE", "length": 557 }, "evidence": [ { "id": "HGNC:23511", "url": "https://alliancegenome.org/gene/HGNC:23511#orthology", "database": "AGR" }, { "id": "MGI:1923820", "url": "https://alliancegenome.org/gene/MGI:1923820#orthology", "database": "AGR" }, { "id": "RGD:1561665", "url": "https://alliancegenome.org/gene/RGD:1561665#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121030-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121030-4#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q53FE4-1", "protein_name": "Uncharacterized protein C4orf17", "gene_name": "C4orf17", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNLNPPTSALQIEGKGSHIMARNVSCFLVRHTPHPRRVCHIKGLNNIPICTVNDDENAFGTLWGVGQSNYLEKNRIPFANCSYPSSTAVQESPVRGMSPAPNGAKVPPRPHSEPSRKIKECFKTSSENPLVIKKEEIKAKRPPSPPKACSTPGSCSSGMTSTKNDVKANTICIPNYLDQEIKILAKLCSILHTDSLAEVLQWLLHATSKEKEWVSALIHSELAEINLLTHHRRNTSMEPAAETGKPPTVKSPPTVKLPPNFTAKSKVLTRDTEGDQPTRVSSQGSEENKEVPKEAEHKPPLLIRRNNMKIPVAEYFSKPNSPPRPNTQESGSAKPVSARSIQEYNLCPQRACYPSTHRR", "length": 359 }, "evidence": [ { "id": "RGD:1309170", "url": "https://alliancegenome.org/gene/RGD:1309170#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TSD4-1", "protein_name": "Protein TBATA", "gene_name": "Tbata", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTEVNQLSEHPLVSPKAEPQPETKPENLPRSHGDVGLQKETVVPGIVDFELIHEELKTTKPQTSQPTPSAYRFGRLSHHSFFSRHHPQPQRVTHIQVTGREDLEHSLPLTTSFQLLQAPGVQPMDLTPSADIAGKPVCVVRDEFSLSALTQPTFLSRCLMGMPTISVPIGDPQSNRNPQLSTSDTWRKKLKDLASRVTVFTKEIQPKPDEQKEEPPLREPPPREQGAKYSAETGRLIPASSQALTRRNRQGQRVHPSSKDGGVQASILQDQELLILELLCQILQTDSLRAIQFWLLYAPSKEKDLALGLLQTAVAQLIPQPLSSIPAEKLWNHLQELQEPQETQEAAYSPSLKKTRSPPLPKTDKPEYIGKAQVLLVHPSEDPEEKTTKAES", "length": 393 }, "evidence": [ { "id": "HGNC:23511", "url": "https://alliancegenome.org/gene/HGNC:23511#orthology", "database": "AGR" }, { "id": "MGI:1923820", "url": "https://alliancegenome.org/gene/MGI:1923820#orthology", "database": "AGR" }, { "id": "RGD:1561665", "url": "https://alliancegenome.org/gene/RGD:1561665#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121030-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121030-4#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96M53-1", "protein_name": "Protein TBATA", "gene_name": "TBATA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATDVQLADYPLMSPKAELKLEKKSGRKPRSPRDSGPQKELVIPGIVDFERIRRALRTPKPQTPGTYCFGRLSHHSFFSRHHPHPQHVTHIQDLTGKPVCVVRDFPAPLPESTVFSGCQMGIPTISVPIGDPQSNRNPQLSSEAWKKELKELASRVAFLTKEDELKKKEKEQKEEPLREQGAKYSAETGRLIPASTRAVGRRRSHQGQQSQSSSRHEGVQAFLLQDQELLVLELLCRILETDLLSAIQFWLLYAPPKEKDLALGLLQTAVAQLLPQPLVSIPTEKLLSQLPEVHEPPQEKQEPPCSQSPKKTKISPFTKSEKPEYIGEAQVLQMHSSQNTEKKTSKPRAES", "length": 351 }, "evidence": [ { "id": "HGNC:23511", "url": "https://alliancegenome.org/gene/HGNC:23511#orthology", "database": "AGR" }, { "id": "MGI:1923820", "url": "https://alliancegenome.org/gene/MGI:1923820#orthology", "database": "AGR" }, { "id": "RGD:1561665", "url": "https://alliancegenome.org/gene/RGD:1561665#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121030-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121030-4#orthology", "database": "AGR" } ], "glygen_name": "Human", 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This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017208420.2. 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Classification" ] }, { "id": "XP_017208420", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208420", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3T7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3T7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z3T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3T7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IAE3", "url": "https://www.uniprot.org/uniprotkb/A0AC58IAE3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IAE3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IAE3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSCISESSHLNKFLRHRYLNLPQGDFCLVTYVWIDSCGVDLYSKTRTMDCEPKILADVPEWDVGLETEESSSEMLLNHVRMFRDPFFLDPNKLILCEVLKHTREPAEWNHRNRCNTLMEKVKDLHPWFGMEQEYTLLGVDGHPYSWPRLGFPKPQGHHTDMMSFYAHSL", "length": 169, "header": "tr|A0A8M6Z3T7-1|A0A8M6Z3T7_DANRE Isoform 1 of Glutamine synthetase-like isoform X1 OS=Danio rerio OX=7955 GN=LOC100535016 PE=4 SV=3 CANONICAL=A0A8M6Z3T7-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z3T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3T7/entry#A0A8M6Z3T7-1", "sequence": { "sequence": "MSCISESSHLNKFLRHRYLNLPQGDFCLVTYVWIDSCGVDLYSKTRTMDCEPKILADVPEWDVGLETEESSSEMLLNHVRMFRDPFFLDPNKLILCEVLKHTREPAEWNHRNRCNTLMEKVKDLHPWFGMEQEYTLLGVDGHPYSWPRLGFPKPQGHHTDMMSFYAHSL", "length": 169, "header": "tr|A0A8M6Z3T7-1|A0A8M6Z3T7_DANRE Isoform 1 of Glutamine synthetase-like isoform X1 OS=Danio rerio OX=7955 GN=LOC100535016 PE=4 SV=3 CANONICAL=A0A8M6Z3T7-1" }, "locus": {} }, { "isoform_ac": "A0AC58IAE3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3T7/entry#A0AC58IAE3-1", "sequence": { "sequence": "MSCISESSHLNKFLRHRYLNLPQGDFCLVTYVWIDSCGVDLYSKTRTMDCEPKILADVPEWDVGLETEESSSEMLLNHVRMFRDPFFLDPNKLILCEVLKHTREPAEWNHRNRCNTLMEKVKDLHPWFGMEQEYTLLGVDGHPYSWPRLGFPKPQGTLRKPLRN", "length": 164, "header": "tr|A0AC58IAE3-1|A0AC58IAE3_DANRE Computationally mapped isoform of Glutamine synthetase-like isoform X2 OS=Danio rerio OX=7955 GN=LOC100535016 PE=4 SV=1 CANONICAL=A0A8M6Z3T7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100535016", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100535016", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3T7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3T7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "glutamine synthetase activity", "id": "GO:0004356", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004356", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3T7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3T7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "glutamine biosynthetic process", "id": "GO:0006542", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006542", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z3T7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z3T7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z442-1", "uniprot_ac": "A0A8M6Z442", "uniprot_id": "A0A8M6Z442_DANRE", "mass": { "chemical_mass": 98788.0, "monoisotopic_mass": 98788.0 }, "refseq": { "ac": "XP_068073234", "name": "uncharacterized protein si:dkey-225n22.4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073234" }, "gene_names": [ { "name": "si:dkey-225n22.4", "type": "recommended", "evidence": [ { "id": "A0A8M6Z442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z442" } ] }, { "name": "si:dkey-225n22.4", "type": "synonym", "evidence": [ { "id": "XP_068073234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073234" } ] } ], "protein_names": [ { "name": "Collagen alpha-1(XXI) chain", "type": "recommended", "evidence": [ { "id": "A0A8M6Z442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z442/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkey-225n22.4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_068073234", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073234" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068073234", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073234" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z442", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z442" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-225n22.4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z442", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120709-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120709-30", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z442", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z442", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01472", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01472", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "792513", "url": "https://www.ncbi.nlm.nih.gov/gene/792513", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:792513", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:792513", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z442", "url": "https://www.orthodb.org/?gene=A0A8M6Z442", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00092", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00092", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_068073234", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073234", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z442", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z442", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z442-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z442-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IT68", "url": "https://www.uniprot.org/uniprotkb/A0AC58IT68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IT68-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IT68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120709-30", "url": "https://zfin.org/ZDB-GENE-120709-30", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSWVWKCVPALIILVFSHAAKDDDVRAGCSTAVNDLVYIMDGSWSVGDVDFETAKRWLINVTSGFDVSSHYSQVGVVQYSDTPRLEIPLGQHKTTQQLIEAIEKISYLGGNTQTGRAIKFAVDHVFPSSRRNDVKNRIAVVVTDGKSQDDVTDASLDARTQGITVFAVGVGSEITNSELVTIANTPAGDYVLFAEDYTNIERIRDAMEQKLCEESVCPTRIPVASRDEKGFELILGMKIHQKAKKIQGSLVSEGAYLLDKTTDITENTRDIFPEGLPPSYVFVSTLRLKGSSSTESFDLWRVKSKDGQIQAAVTLSGLQKYISFTTTNTFNQEQTVVFDAPGIEAVFDGSWHQLKVLVKPRQVICYLDDQEIQDEPLDPVVPIFINGKTQISKRSGSDASVPTEIQKLRLYCDPQQSERETACEIYSVDDERCPLDREPTFEEECDCDETQPGPPGPPGPPGARGFRGEKGREGPPGPDGKPGPPGLRGEPGYVGPPGPKGDVGLSGPRGDPGLQGFKGDQGDQGLPGRPGPPGPMGASKPSIGIAGLPGEKGAQGGKGEQGPPGKPGLMGVPGIPGNEGPPGPAGAQGEKGDDGPPGAAGPQGPPGIRGLSGEAGATGEQGARGAPGPKGSPGPRGAQGAQGPSGTPGADGARGPKGSAGETGGAGAPGAAGQKGQQGESGFPGAQGATGLPGFKGHKGERGESGPRGAQGEKGTKGFPGLPGFTGETGPRGIKGERGSPGDPGLKGPDGQKGDMGHIGVVGPRGFPGQDGLPGQPGNPGFPGKPGKPPSDEYFIKLCRDVLRNQLPQLLQTMSSQRCEPCETIKGPPGHPGAPGPKGSIGSPGYPGRHGAQGYPGPPGVQGPPGVKGDTGIQGFKGKKGESRPGYPGPPGDTGIQGPRGSDGIGFPGPPGIPGKSGSPGIPGKQGPPGQAGVCDMSICYQSYNLREERYSKGPDF", "length": 957, "header": "tr|A0A8M6Z442-1|A0A8M6Z442_DANRE Isoform 1 of Collagen alpha-1(XXI) chain OS=Danio rerio OX=7955 GN=si:dkey-225n22.4 PE=3 SV=1 CANONICAL=A0A8M6Z442-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z442-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z442/entry#A0A8M6Z442-1", "sequence": { "sequence": "MSWVWKCVPALIILVFSHAAKDDDVRAGCSTAVNDLVYIMDGSWSVGDVDFETAKRWLINVTSGFDVSSHYSQVGVVQYSDTPRLEIPLGQHKTTQQLIEAIEKISYLGGNTQTGRAIKFAVDHVFPSSRRNDVKNRIAVVVTDGKSQDDVTDASLDARTQGITVFAVGVGSEITNSELVTIANTPAGDYVLFAEDYTNIERIRDAMEQKLCEESVCPTRIPVASRDEKGFELILGMKIHQKAKKIQGSLVSEGAYLLDKTTDITENTRDIFPEGLPPSYVFVSTLRLKGSSSTESFDLWRVKSKDGQIQAAVTLSGLQKYISFTTTNTFNQEQTVVFDAPGIEAVFDGSWHQLKVLVKPRQVICYLDDQEIQDEPLDPVVPIFINGKTQISKRSGSDASVPTEIQKLRLYCDPQQSERETACEIYSVDDERCPLDREPTFEEECDCDETQPGPPGPPGPPGARGFRGEKGREGPPGPDGKPGPPGLRGEPGYVGPPGPKGDVGLSGPRGDPGLQGFKGDQGDQGLPGRPGPPGPMGASKPSIGIAGLPGEKGAQGGKGEQGPPGKPGLMGVPGIPGNEGPPGPAGAQGEKGDDGPPGAAGPQGPPGIRGLSGEAGATGEQGARGAPGPKGSPGPRGAQGAQGPSGTPGADGARGPKGSAGETGGAGAPGAAGQKGQQGESGFPGAQGATGLPGFKGHKGERGESGPRGAQGEKGTKGFPGLPGFTGETGPRGIKGERGSPGDPGLKGPDGQKGDMGHIGVVGPRGFPGQDGLPGQPGNPGFPGKPGKPPSDEYFIKLCRDVLRNQLPQLLQTMSSQRCEPCETIKGPPGHPGAPGPKGSIGSPGYPGRHGAQGYPGPPGVQGPPGVKGDTGIQGFKGKKGESRPGYPGPPGDTGIQGPRGSDGIGFPGPPGIPGKSGSPGIPGKQGPPGQAGVCDMSICYQSYNLREERYSKGPDF", "length": 957, "header": "tr|A0A8M6Z442-1|A0A8M6Z442_DANRE Isoform 1 of Collagen alpha-1(XXI) chain OS=Danio rerio OX=7955 GN=si:dkey-225n22.4 PE=3 SV=1 CANONICAL=A0A8M6Z442-1" }, "locus": {} }, { "isoform_ac": "A0AC58IT68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z442/entry#A0AC58IT68-1", "sequence": { "sequence": "MKPSRDLQDPRDLQEHGVFEERKEGKDPRAQMGPPGLRGEPGYVGPPGPKGDVGLSGPRGDPGLQGFKGDQGDQGLPGRPGPPGPMGASKPSIGIAGLPGEKGAQGGKGEQGPPGKPGLMGVPGIPGNEGPPGPAGAQGEKGDDGPPGAAGPQGPPGIRGLSGEAGATGEQGARGAPGPKGSPGPRGAQGAQGPSGTPGADGARGPKGSAGETGGAGAPGAAGQKGQQGESGFPGAQGATGLPGFKGHKGERGESGPRGAQGEKGTKGFPGLPGFTGETGPRGIKGERGSPGDPGLKGPDGQKGDMGHIGVVGPRGFPGQDGLPGQPGNPGFPGKPGKPPSDEYFIKLCRDVLRNQLPQLLQTMSSQRCEPCETIKGPPGHPGAPGPKGSIGSPGYPGRHGAQGYPGPPGVQGPPGVKGDTGIQGFKGKKGESRPGYPGPPGDTGIQGPRGSDGIGFPGPPGIPGKSGSPGIPGKQGPPGQAGVCDMSICYQSYNLREERYSKGPDF", "length": 507, "header": "tr|A0AC58IT68-1|A0AC58IT68_DANRE Computationally mapped isoform of Uncharacterized protein si:dkey-225n22.4 isoform X2 OS=Danio rerio OX=7955 GN=si:dkey-225n22.4 PE=4 SV=1 CANONICAL=A0A8M6Z442-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 647, "start_aa": "Thr", "end_pos": 647, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr647", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:792513", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:792513", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z442", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z442" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z442", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z442" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z442", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z442" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 207, "start_aa": "Asp", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 647 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z466-1", "uniprot_ac": "A0A8M6Z466", "uniprot_id": "A0A8M6Z466_DANRE", "mass": { "chemical_mass": 87578.0, "monoisotopic_mass": 87578.0 }, "refseq": { "ac": "XP_017214533", "name": "protocadherin alpha-6-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214533" }, "gene_names": [ { "name": "LOC108192085", "type": "recommended", "evidence": [ { "id": "A0A8M6Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466" } ] }, { "name": "LOC108192085", "type": "synonym", "evidence": [ { "id": "XP_017214533", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214533" } ] } ], "protein_names": [ { "name": "Protocadherin alpha-6-like", "type": "synonym", "evidence": [ { "id": "A0A8M6Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466/entry#names_and_taxonomy" } ] }, { "name": "protocadherin alpha-6-like", "type": "synonym", "evidence": [ { "id": "XP_017214533", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214533" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017214533.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214533" } ] }, { "annotation": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466#function" }, { "database": "UniProtKB", "id": "ARBA00003436", "url": "https://www.uniprot.org/uniprotkb/ARBA00003436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108192085", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z466", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z466", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "108192085", "url": "https://www.ncbi.nlm.nih.gov/gene/108192085", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108192085", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108192085", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z466", "url": "https://www.orthodb.org/?gene=A0A8M6Z466", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017214533", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214533", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z466-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEAGGQRHRRENCCIALCIYFLIIEEQVSAQIRYSVPEEVKEGTVVGNIAKDLGLEVSSLVDRQFRIVSGSKEELFQINQDNGVLYVHKKIDRESLCVGSGVCMVNLKTLIENPLEMHYVEVEILDINDHSPIFSEKEERLRIYENTQPGADYQLQAARDADSGSNSVRSYKLTPNDNFEIQVRENDEDKVPFLVLKKAVDREITTAYNLLLTAVDGGNPPKSGALNITITILDINDNRPVFSRETYSATLQENSVIDTVVLKVNATDKDEGLNGDIEYSFAKLNLKVQEVFELDQVTGEIRVKGAVDFEDTEVYKLDIQASDKGHPPMFAKSRVVIKIIDVNDNSPEIEITSLSKNIPEDCKPGTVISLISVTDKDAGINGKVICQLNKNVPFELKPSFKDNMYSLVTKDRLDRETHSQYDITITASDLGQPSLTASTTLSVQISDVNDNAPEFSINPLDLYLMENNAAGSSIISVSASDKDSAENAVISYHIIRGDGSQTDMSSYLNINSETGVVYSLKSFDFEMLKTFHFHVLATDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSEHSLFALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNVSLSATATVIVKVVEPKEAFAASDVKKAEKDEEENNVTFYLIITLGSVSVLFVISIIVLIVMQCSKSTDYSSKYLQDTNYDGTLCHSIQYRSGDKRYMLVGPRMSIGSTIAPGSNRNTLVIPDRRRRDSGEVRITH", "length": 790, "header": "tr|A0A8M6Z466-1|A0A8M6Z466_DANRE Isoform 1 of Protocadherin alpha-6-like OS=Danio rerio OX=7955 GN=LOC108192085 PE=4 SV=3 CANONICAL=A0A8M6Z466-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z466-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466/entry#A0A8M6Z466-1", "sequence": { "sequence": "MEAGGQRHRRENCCIALCIYFLIIEEQVSAQIRYSVPEEVKEGTVVGNIAKDLGLEVSSLVDRQFRIVSGSKEELFQINQDNGVLYVHKKIDRESLCVGSGVCMVNLKTLIENPLEMHYVEVEILDINDHSPIFSEKEERLRIYENTQPGADYQLQAARDADSGSNSVRSYKLTPNDNFEIQVRENDEDKVPFLVLKKAVDREITTAYNLLLTAVDGGNPPKSGALNITITILDINDNRPVFSRETYSATLQENSVIDTVVLKVNATDKDEGLNGDIEYSFAKLNLKVQEVFELDQVTGEIRVKGAVDFEDTEVYKLDIQASDKGHPPMFAKSRVVIKIIDVNDNSPEIEITSLSKNIPEDCKPGTVISLISVTDKDAGINGKVICQLNKNVPFELKPSFKDNMYSLVTKDRLDRETHSQYDITITASDLGQPSLTASTTLSVQISDVNDNAPEFSINPLDLYLMENNAAGSSIISVSASDKDSAENAVISYHIIRGDGSQTDMSSYLNINSETGVVYSLKSFDFEMLKTFHFHVLATDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSEHSLFALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNVSLSATATVIVKVVEPKEAFAASDVKKAEKDEEENNVTFYLIITLGSVSVLFVISIIVLIVMQCSKSTDYSSKYLQDTNYDGTLCHSIQYRSGDKRYMLVGPRMSIGSTIAPGSNRNTLVIPDRRRRDSGEVRITH", "length": 790, "header": "tr|A0A8M6Z466-1|A0A8M6Z466_DANRE Isoform 1 of Protocadherin alpha-6-like OS=Danio rerio OX=7955 GN=LOC108192085 PE=4 SV=3 CANONICAL=A0A8M6Z466-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108192085", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108192085", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z466", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z466", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z466" }, { "id": "PS50268", "database": "PROSITE", "url": 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annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel internal stop codons :: corrected 1 genomic stop codon ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017208884.2. 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"pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z493", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z493" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z493", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z493" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA polymerase II-specific", "id": "GO:0001227", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001227", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z493", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z493" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z493", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z493" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z493", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z493" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 83, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], 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"protein_names": [ { "name": "Engulfment and cell motility protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z4G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1/entry#names_and_taxonomy" } ] }, { "name": "engulfment and cell motility protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017209693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209693" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017209693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209693" } ] }, { "annotation": "Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4G1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1#function" }, { "database": "UniProtKB", "id": "ARBA00024863", "url": "https://www.uniprot.org/uniprotkb/ARBA00024863#function" }, { "database": "UniProtKB", "id": "F1QSV8", "url": "https://www.uniprot.org/uniprotkb/F1QSV8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4G1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "elmo3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050309-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050309-39", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z4G1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z4G1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000042126", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000042126", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13359", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13359", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "553310", "url": "https://www.ncbi.nlm.nih.gov/gene/553310", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:553310", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553310", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KIAIQMM", "url": "https://omabrowser.org/oma/group/KIAIQMM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z4G1", "url": "https://www.orthodb.org/?gene=A0A8M6Z4G1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1QSV8", "url": "https://www.orthodb.org/?gene=F1QSV8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12771:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12771:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16457", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16457", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26964", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26964", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017209693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209693", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4G1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PHA9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PHA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QSV8", "url": "https://www.uniprot.org/uniprotkb/F1QSV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QSV8-1", "url": "https://www.uniprot.org/uniprotkb/F1QSV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050309-39", "url": "https://zfin.org/ZDB-GENE-050309-39", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPQQKDIVKIAIQMPGAYPQLIQLDQKKPLTSVIKEVCDKWNLPGPENYALQYADGIQTYITESNRLDIKNGSILRLTKAPGRCAEDLYKGIQSSDSNVRCDSLNLLAIVSTDITFAQEFISRDGHSLLVKIVEDAQESPVIMTHTLTAFMELMDHGIVSWENLSSVFIKKMASFVNAKVLDTSIQQVSLAILESMVLSSSSLFTEVKQEITLERLLSHLQVYVDYTIHTRTNQQLQTKAMALLMALLQAGGEADRQELFEFLEKRNLRQYIHKNIIHSSSSVGDEMAHYLYVLQTVRLNHLEPRMKTPLDSYSQEQREMLHGLRQAAFETESESGLSNERRRSLCAKEFKKLGFSNNSNPGQDLSRCPPGLLALDTMAYFASRYPDAYSRFVLENSSREDKHECPFARSSIQLTLILCEILRIGEPPSETGSDYHPIFFAQDRLLEELFCICIQLLNKTWKEMRATQEDFDKVMQVVREQITRTLASKPTSLELFKNKVNALNYSEILKLRQTERLHQEETLAPPVLELKERLKPELLELIRQQRLNRLCHGTLFRKMSSRRRQDKLWYCRLSPNHKVLHYGDVEEETEMPSIEALQDKIPVADIKNVVTGKDCPHMKENKGKQTKEVLDLAFSITYDVEEYSLNFIASSRTDFCLWTDGLSVLLGKEMSSESMRSELEILLSMEIKLRLLDLENVPIPDAAPPIPKPPSNFNFCYDFSQTEQ", "length": 724, "header": "tr|A0A8M6Z4G1-1|A0A8M6Z4G1_DANRE Isoform 1 of Engulfment and cell motility protein 3 isoform X1 OS=Danio rerio OX=7955 GN=elmo3 PE=1 SV=1 CANONICAL=A0A8M6Z4G1-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z4G1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1/entry#A0A8M6Z4G1-1", "sequence": { "sequence": "MPQQKDIVKIAIQMPGAYPQLIQLDQKKPLTSVIKEVCDKWNLPGPENYALQYADGIQTYITESNRLDIKNGSILRLTKAPGRCAEDLYKGIQSSDSNVRCDSLNLLAIVSTDITFAQEFISRDGHSLLVKIVEDAQESPVIMTHTLTAFMELMDHGIVSWENLSSVFIKKMASFVNAKVLDTSIQQVSLAILESMVLSSSSLFTEVKQEITLERLLSHLQVYVDYTIHTRTNQQLQTKAMALLMALLQAGGEADRQELFEFLEKRNLRQYIHKNIIHSSSSVGDEMAHYLYVLQTVRLNHLEPRMKTPLDSYSQEQREMLHGLRQAAFETESESGLSNERRRSLCAKEFKKLGFSNNSNPGQDLSRCPPGLLALDTMAYFASRYPDAYSRFVLENSSREDKHECPFARSSIQLTLILCEILRIGEPPSETGSDYHPIFFAQDRLLEELFCICIQLLNKTWKEMRATQEDFDKVMQVVREQITRTLASKPTSLELFKNKVNALNYSEILKLRQTERLHQEETLAPPVLELKERLKPELLELIRQQRLNRLCHGTLFRKMSSRRRQDKLWYCRLSPNHKVLHYGDVEEETEMPSIEALQDKIPVADIKNVVTGKDCPHMKENKGKQTKEVLDLAFSITYDVEEYSLNFIASSRTDFCLWTDGLSVLLGKEMSSESMRSELEILLSMEIKLRLLDLENVPIPDAAPPIPKPPSNFNFCYDFSQTEQ", "length": 724, "header": "tr|A0A8M6Z4G1-1|A0A8M6Z4G1_DANRE Isoform 1 of Engulfment and cell motility protein 3 isoform X1 OS=Danio rerio OX=7955 GN=elmo3 PE=1 SV=1 CANONICAL=A0A8M6Z4G1-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PHA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1/entry#A0A8M9PHA9-1", "sequence": { "sequence": "MAEVMQVVREQITRTLASKPTSLELFKNKVNALNYSEILKLRQTERLHQEETLAPPVLELKERLKPELLELIRQQRLNRLCHGTLFRKMSSRRRQDKLWYCRLSPNHKVLHYGDVEEETEMPSIEALQDKIPVADIKNVVTGKDCPHMKENKGKQTKEVLDLAFSITYDVEEYSLNFIASSRTDFCLWTDGLSVLLGKEMSSESMRSELEILLSMEIKLRLLDLENVPIPDAAPPIPKPPSNFNFCYDFSQTEQ", "length": 254, "header": "tr|A0A8M9PHA9-1|A0A8M9PHA9_DANRE Computationally mapped isoform of Engulfment and cell motility protein 3 isoform X3 OS=Danio rerio OX=7955 GN=elmo3 PE=1 SV=1 CANONICAL=A0A8M6Z4G1-1" }, "locus": {} }, { "isoform_ac": "F1QSV8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1/entry#F1QSV8-1", "sequence": { "sequence": "MPQQKDIVKIAIQMPGAYPQLIQLDQKKPLTSVIKEVCDKWNLPGPENYALQYADGIQTYITESNRLDIKNGSILRLTKAPGRCAEDLYKGIQSSDSNVRCDSLNLLAIVSTDITFAQEFISRDGHSLLVKIVEDAQESPVIMTHTLTAFMELMDHGIVSWENLSSVFIKKMASFVNAKVLDTSIQQVSLAILESMVLSSSSLFTEVKQEITLERLLSHLQVTNQQLQTKAMALLMALLQAGGEADRQELFEFLEKRNLRQYIHKNIIHSSSSVGDEMAHYLYVLQTVRLNHLEPRMKTPLDSYSQEQREMLHGLRQAAFETESESGLSNERRRSLCAKEFKKLGFSNNSNPGQDLSRCPPGLLALDTMAYFASRYPDAYSRFVLENSSREDKHECPFARSSIQLTLILCEILRIGEPPSETGSDYHPIFFAQDRLLEELFCICIQLLNKTWKEMRATQEDFDKVMQVVREQITRTLASKPTSLELFKNKVNALNYSEILKLRQTERLHQEETLAPPVLELKERLKPELLELIRQQRLNRLCHGTLFRKMSSRRRQDKLWYCRLSPNHKVLHYGDVEEETEMPSIEALQDKIPVADIKNVVTGKDCPHMKENKGKQTKEVLDLAFSITYDVEEYSLNFIASSRTDFCLWTDGLSVLLGKEMSSESMRSELEILLSMEIKLRLLDLENVPIPDAAPPIPKPPSNFNFCYDFSQTEQ", "length": 715, "header": "tr|F1QSV8-1|F1QSV8_DANRE Computationally mapped isoform of Engulfment and cell motility protein 3 isoform X2 OS=Danio rerio OX=7955 GN=elmo3 PE=1 SV=1 CANONICAL=A0A8M6Z4G1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:553310", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553310", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6G6K9-1", "protein_name": "Engulfment and cell motility 2", "gene_name": "Elmo2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQQLSPEVGPLGTMPPPSDIVKVAIEWPGANAQLLEIDQKRPLASVIKEVCDGWSLPNPEYYTLRYADGPQLYVTEQTRSDIKNGTILQLAISPSRAARQLMERTQSSSMETRLDAMKELAKLSADVTFATEFINMDGIVVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDLVSITFIKQIAGYVSQPMADVSVLQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINPALDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWHCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFVYHYG", "length": 734 }, "evidence": [ { "id": "FB:FBgn0032409", "url": "https://alliancegenome.org/gene/FB:FBgn0032409#orthology", "database": "AGR" }, { "id": "SGD:S000003930", "url": "https://alliancegenome.org/gene/SGD:S000003930#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58GP09-1", "protein_name": "Engulfment and cell motility protein 2 isoform X1", "gene_name": "elmo2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPPPSDIVKVAIEWPGANAQLIEIDQKKPLASIIREVCEGWSLSGSEQFALRYADGPQLYITEQTRGEIKNGTILRLAISPMRAARQLLERIQSHSIDARLEALKELAKLSADAAFASEFINIDGLVTLARLVESGTHFGEMLAFTLTAFLELMDHGIVSWELLSLSFIKQIAGYVNQPMVDVSILQRSLAILESMVLNSHSLYQRVAQETTVAQLITHLQVSNQEIQTYAIALINALFLKTPEDRRQEMAATLAQRHLRAIILNHIIRGNRPVKAEMAHQLYVLQVLTFNLLEERMMTKMDPNDQTQRDVIFELRRIAFDGDAAEPSGTEKRKAAAHTKDYRMLGFSNAVNPALDFTQTPPGMLALDNMLYLAKLHQDTYIRIVLENSSREDKHECPFARCAIELTRVLCDILQVGELPNEGCNDFHPMFFTHERAWEEFFCVCIQLLNKTWKEMRATAEDFNKVMTVVREQITRALALKPASLDQLRLKLRSLSYSEILRLRQSERMSQDDFQSPPIIELRERIQPEILELIKQQRLSRLCEGSCFRKLGNRRRQEKFWFCRLSLNHKLLHYGDLEESPQGEVPLELLTDKIAVSDIKAVLTGKDCPHMKEKSALKQNKEVLELAFSILYDPDESLNFVAPNKYEYCIWTDGLSALLGKDLSSDLTRSDLDTLMSMEMKLRLLDLENITIPEAPPPVPKEPSSYNFSYNYG", "length": 713 }, "evidence": [ { "id": "FB:FBgn0032409", "url": "https://alliancegenome.org/gene/FB:FBgn0032409#orthology", "database": "AGR" }, { "id": "SGD:S000003930", "url": "https://alliancegenome.org/gene/SGD:S000003930#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6QR40-1", "protein_name": "Engulfment and cell motility protein 3", "gene_name": "ELMO3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPPRNVVKIAVQMRDAIPQLIQLDQAKPLAAVLKEVCDAWSLPHSERYALQFADGHRRYITENNRMEIKNGSILCLSTAPDREAERLLRGLQSESREGRREALRHLLLLAPDLTFAREVISRDGLQRLGTIIEDGDDLGEVLALALRAFLELMEHGVVSWETLSIPFVRKVVCYVNMNLMDASVQPLALGLLENVTLSSPTLGQLVKSEVPLDRLLVHLQVMNQQLQTKAMALLTALLQGATPAERKHMLDYLWQRNLRQFIYKNIIHSAAPLGDEMAHHLYVLQALMLGLLEPRMRTPLDPYSQEQREQLQALRQAAFEPEGESVGAGLSADRRRSLCAREFRKLGFSNSNPAQDLERVPPGLLALDNMLYFSRQAPSAYSRFVLENSSREDKHECPFARSSIQLTVLLCDLLHVGEPCSETAQDFSPMFFGQDQSFHELFCVSIQLLNKTWKEMRATQEDFDKVMQVVREQLARTLALKPSSLELFRTKVNALTYGEVLRLRQTERLHQEGTLAPPILELREKLKPELMGLIRQQRLLRLCEGTLFHKISSRRRQDKLWFCCLSPNHKVLQYGDVEEGVGPPTPESLPEQLPVADIRALLTGKDCPHVREKGSGKQNKDVCELAFSVSYDHGEEEAYLNFIAPSKREMG", "length": 652 }, "evidence": [ { "id": "A0A8M6Z4G1", "url": "https://omabrowser.org/oma/group/A0A8M6Z4G1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q07799-1", "protein_name": "ELMO family protein LMO1", "gene_name": "LMO1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKHNRQMPDESLENIKVLLNPKLGKPVKSLTSAQSKACYHTLISNKNLNKTSDEYEKLLANYILLCDEKYLCKTVIPDSRFWAILCDNCQKLRSETLVANLIRIFNVALKCQDSNKNEVIVSICHISRENSQLIGILLQLLSQRPIHIPLFTDTILCITLFLKCSLTLCETSLSHAVEFVPRILILLFQYNFPASMSELLYIEDLQPLILEEFVPLKQRLINFLSSVSIDDYSCSLKADLLTAIKDNSVFQKGLEMEMGDLPSINLLNAYDTFTFLNSPNGSFKRLYTEQLLFGENDFPLYEAIFKLSDQFRRLFNLSGKKENQYSDSERDLKLQIATAVLNRQTCFYKTLELFLRFWIESLAKSQSDLVSLLNLAIITLKYVCLSSSDLEAAIQTKSLLKTQVVALDSMRYKFARTLQLDSIKKEQYRTWSSSIASFDTMLSGQVRDYVRHQRLLQLQKGTWVYAENPLNPEAGTPKVYFLIVSDNHANLLAREFETQTNDLPYLFDNKILTSPGSEALANGRTKVVVLKHITSFKSIELTTPSRRTSSNVYIKLDEANVYTGVELKDRNDRTVLKFYLDTEEGRYIWLDGLKLISPFQHEDISEDTKEQIDTLFDLRKNVQMINLNVRQDIIVPPPEPSDEDEDEEFYNLETLKKVTQNFYFD", "length": 665 }, "evidence": [ { "id": "MGI:2679007", "url": "https://alliancegenome.org/gene/MGI:2679007#orthology", "database": "AGR" }, { "id": "HGNC:17289", "url": "https://alliancegenome.org/gene/HGNC:17289#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050309-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050309-39#orthology", "database": "AGR" }, { "id": "FB:FBgn0032409", "url": "https://alliancegenome.org/gene/FB:FBgn0032409#orthology", "database": "AGR" }, { "id": "RGD:1304734", "url": "https://alliancegenome.org/gene/RGD:1304734#orthology", "database": "AGR" }, { "id": "SGD:S000003930", "url": "https://alliancegenome.org/gene/SGD:S000003930#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q499U2-1", "protein_name": "Engulfment and cell motility protein 3", "gene_name": "Elmo3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPPRNVVKIAVQMSDAIPQLIQLDQAKPLATVLKEVCDTWSLTHPEHYALQFADGHRKYITENNRSEIKNGSILCLSTAPDLKAQQLLSRLQNASREGCCEVLRNLVPLASDMTFAQEVISRDGLQKLSTIIENGDDLGEMLALGLRAFLELMEHGVVSWETLSISFVRKVVSYVNMNLMDASVQPLALRLLESVTLSSPTLGQLVKSEVPLDRLLVHLQVMNQQLQTKAMALLTALLQGASPAERKDMLDCLWKKNLRQFIYKNIIHSAAPMGDEMAHHLYVLQALTLGLLEPRMRTPLDPYSQEQREQLQALRQAAFEPDGESLGTGLSADRRRSLCVREFRKLGFSNSSPAQDLERVPPGLLALDNMLYFSRHAPSAYSRFVLENSSREDKHECPFARSSIQLTVLLCELLHVGEPCSETAQDFSPMFFSQDHSFHELFCVAIQLLNKTWKEMRATQEDFDKVMQVVREQLARTLALKPTSLELFRTKVNALTYGEVLRLRQTERLHQEGTLAPPILELREKLKPELMGLIRQQRLLRLCEGMLFRKISSRRRQDKLWFCCLSPNHKVLQYGDVEEGANPPTLESLTEQLPVADIRALLMGKDCPHVREKGSGKQNKDLYELAFSISYDHGEEEAYLNFIAPSKRDFYLWTDGLSALLGSTMGSEQTRLDLEQLLTMETKLRLLELENVPIPEHPPPVPPPPTNFNFCYDYSMTEP", "length": 720 }, "evidence": [ { "id": "MGI:2679007", "url": "https://alliancegenome.org/gene/MGI:2679007#orthology", "database": "AGR" }, { "id": "HGNC:17289", "url": "https://alliancegenome.org/gene/HGNC:17289#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050309-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050309-39#orthology", "database": "AGR" }, { "id": "FB:FBgn0032409", "url": "https://alliancegenome.org/gene/FB:FBgn0032409#orthology", "database": "AGR" }, { "id": "RGD:1304734", "url": "https://alliancegenome.org/gene/RGD:1304734#orthology", "database": "AGR" }, { "id": "SGD:S000003930", "url": "https://alliancegenome.org/gene/SGD:S000003930#orthology", "database": "AGR" }, { "id": "A0A8M6Z4G1", "url": "https://omabrowser.org/oma/group/A0A8M6Z4G1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BHL5-1", "protein_name": "Engulfment and cell motility protein 2", "gene_name": "Elmo2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYVTEQTRNDIKNGTILQLAVSPSRAARQLMERTQSSSMETRLDAMKELAKLSADVTFATEFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSVTFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDKHLNPLDLPVTDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNVPGSGTEKRKAMYTKDYKMLGFTNHINPALDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWHCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPVPKEPSSYDFVYHYG", "length": 732 }, "evidence": [ { "id": "FB:FBgn0032409", "url": "https://alliancegenome.org/gene/FB:FBgn0032409#orthology", "database": "AGR" }, { "id": "SGD:S000003930", "url": "https://alliancegenome.org/gene/SGD:S000003930#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BPU7-1", "protein_name": "Engulfment and cell motility protein 1", "gene_name": "Elmo1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPPSDIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGTDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRYIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN", "length": 727 }, "evidence": [ { "id": "FB:FBgn0032409", "url": "https://alliancegenome.org/gene/FB:FBgn0032409#orthology", "database": "AGR" }, { "id": "SGD:S000003930", "url": "https://alliancegenome.org/gene/SGD:S000003930#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYZ7-1", "protein_name": "Engulfment and cell motility protein 3", "gene_name": "Elmo3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPPRNVVKIAVQMSDAIPQLIQLDQAKPLATVLKEVCDAWSLTHPEHYALQFADGHRKYITENNRLEIKNGSILCLSTAPDLKAQQLLGRLQNTSREGCCEVLRNLVLLASDMTFAQEVISRDGLQKLSTIIENGDDLGEMLALGLRAFLELMEHGVVSWETLSISFVRKVISYVNMNLMDASVQPLALRLLESVTLSSPALGQLVKSEVPLDRLLVHLQVMNHQLQTKAMALLTALLQGASPTERKEMLDHLWKKNLRQFIYKNIIHSATPMGDEMAHHLYVLQALTLGLLEPRMRTPLDPYSQEQRDQLQALRQAAFEPEGESLGTGLSADRRRSLCVREFRKLGFSNSNPAQDLERVPPGLLALDNMLYFSRHAPSAYSRFVLENSSREDKHECPFARSSIQLTALLCELLRVGEPCSETAQDFSPMFFSQDHSFHELFCVAIQLLNKTWKEMRATQEDFDKVMQVVREQLARTLALKPTSLELFRTKVNALTYGEVLRLRQTERLHQEGTLAPPILELREKLKPELMGLIRQQRLLRLCEGMLFRKISSRRRQDKLWFCCLSPNHKVLQYGDVEEGAKPPTLESLPEQLPVADIRALLMGKDCPHVREKGSGKQNKDLYELAFSISYDHGEEEAYLNFIAPSKRDFYLWTDGLSALLGSTMGSELTRLDLEQLLTMETKLRLLELENVPIPEQPPPVPPPPTNFNFCYDYSITEP", "length": 720 }, "evidence": [ { "id": "MGI:2679007", "url": "https://alliancegenome.org/gene/MGI:2679007#orthology", "database": "AGR" }, { "id": "HGNC:17289", "url": "https://alliancegenome.org/gene/HGNC:17289#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050309-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050309-39#orthology", "database": "AGR" }, { "id": "FB:FBgn0032409", "url": "https://alliancegenome.org/gene/FB:FBgn0032409#orthology", "database": "AGR" }, { "id": "RGD:1304734", "url": "https://alliancegenome.org/gene/RGD:1304734#orthology", "database": "AGR" }, { "id": "SGD:S000003930", "url": "https://alliancegenome.org/gene/SGD:S000003930#orthology", "database": "AGR" }, { "id": "A0A8M6Z4G1", "url": "https://omabrowser.org/oma/group/A0A8M6Z4G1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92556-1", "protein_name": "Engulfment and cell motility protein 1", "gene_name": "ELMO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPPADIVKVAIEWPGAYPKLMEIDQKKPLSAIIKEVCDGWSLANHEYFALQHADSSNFYITEKNRNEIKNGTILRLTTSPAQNAQQLHERIQSSSMDAKLEALKDLASLSRDVTFAQEFINLDGISLLTQMVESGTERYQKLQKIMKPCFGDMLSFTLTAFVELMDHGIVSWDTFSVAFIKKIASFVNKSAIDISILQRSLAILESMVLNSHDLYQKVAQEITIGQLIPHLQGSDQEIQTYTIAVINALFLKAPDERRQEMANILAQKQLRSIILTHVIRAQRAINNEMAHQLYVLQVLTFNLLEDRMMTKMDPQDQAQRDIIFELRRIAFDAESEPNNSSGSMEKRKSMYTRDYKKLGFINHVNPAMDFTQTPPGMLALDNMLYFAKHHQDAYIRIVLENSSREDKHECPFGRSSIELTKMLCEILKVGELPSETCNDFHPMFFTHDRSFEEFFCICIQLLNKTWKEMRATSEDFNKVMQVVKEQVMRALTTKPSSLDQFKSKLQNLSYTEILKIRQSERMNQEDFQSRPILELKEKIQPEILELIKQQRLNRLVEGTCFRKLNARRRQDKFWYCRLSPNHKVLHYGDLEESPQGEVPHDSLQDKLPVADIKAVVTGKDCPHMKEKGALKQNKEVLELAFSILYDSNCQLNFIAPDKHEYCIWTDGLNALLGKDMMSDLTRNDLDTLLSMEIKLRLLDLENIQIPDAPPPIPKEPSNYDFVYDCN", "length": 727 }, "evidence": [ { "id": "FB:FBgn0032409", "url": "https://alliancegenome.org/gene/FB:FBgn0032409#orthology", "database": "AGR" }, { "id": "SGD:S000003930", "url": "https://alliancegenome.org/gene/SGD:S000003930#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96BJ8-1", "protein_name": "Engulfment and cell motility protein 3", "gene_name": "ELMO3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPPRNVVKIAIKMRDAIPQLIQLDQAKPLAAVLKEVCDAWSLTHSERYALQFADGHRRYITENNRAEIKNGSILCLSTAPDLEAEQLLGGLQSNSPEGRREALRRLVPLASDMIFAREVISRNGLQILGTIIEDGDDLGEVLALSLRAFSELMEHGVVSWETLSIPFVRKVVCYVNMNLMDASVPPLALGLLESVTLSSPALGQLVKSEVPLDRLLVHLQVMNQQLQTKAMALLTALLQGASPVERKHMLDYLWQRNLRQFIYKNIIHSAAPMGDEMAHHLYVLQALMLGLLEPRMRTPLDPYSQEQREQLQVLRQAAFEVEGESSGAGLSADRRRSLCAREFRKLGFSNSNPAQDLERVPPGLLALDNMLYFSRNAPSAYSRFVLENSSREDKHECPFARGSIQLTVLLCELLRVGEPCSETAQDFSPMFFGQDQSFHELFCVGIQLLNKTWKEMRATQEDFDKVMQVVREQLARTLALKPTSLELFRTKVNALTYGEVLRLRQTERLHQEGTLAPPILELREKLKPELMGLIRQQRLLRLCEGTLFRKISSRRRQDKLWFCCLSPNHKLLQYGDMEEGASPPTLESLPEQLPVADMRALLTGKDCPHVREKGSGKQNKDLYELAFSISYDRGEEEAYLNFIAPSKREFYLWTDGLSALLGSPMGSEQTRLDLEQLLTMETKLRLLELENVPIPERPPPVPPPPTNFNFCYDCSIAEP", "length": 720 }, "evidence": [ { "id": "MGI:2679007", "url": "https://alliancegenome.org/gene/MGI:2679007#orthology", "database": "AGR" }, { "id": "HGNC:17289", "url": "https://alliancegenome.org/gene/HGNC:17289#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050309-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050309-39#orthology", "database": "AGR" }, { "id": "FB:FBgn0032409", "url": "https://alliancegenome.org/gene/FB:FBgn0032409#orthology", "database": "AGR" }, { "id": "RGD:1304734", "url": "https://alliancegenome.org/gene/RGD:1304734#orthology", "database": "AGR" }, { "id": "SGD:S000003930", "url": "https://alliancegenome.org/gene/SGD:S000003930#orthology", "database": "AGR" }, { "id": "A0A8M6Z4G1", "url": "https://omabrowser.org/oma/group/A0A8M6Z4G1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96JJ3-1", "protein_name": "Engulfment and cell motility protein 2", "gene_name": "ELMO2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPPSDIVKVAIEWPGANAQLLEIDQKRPLASIIKEVCDGWSLPNPEYYTLRYADGPQLYITEQTRSDIKNGTILQLAISPSRAARQLMERTQSSNMETRLDAMKELAKLSADVTFATEFINMDGIIVLTRLVESGTKLLSHYSEMLAFTLTAFLELMDHGIVSWDMVSITFIKQIAGYVSQPMVDVSILQRSLAILESMVLNSQSLYQKIAEEITVGQLISHLQVSNQEIQTYAIALINALFLKAPEDKRQDMANAFAQKHLRSIILNHVIRGNRPIKTEMAHQLYVLQVLTFNLLEERMMTKMDPNDQAQRDIIFELRRIAFDAESDPSNAPGSGTEKRKAMYTKDYKMLGFTNHINPAMDFTQTPPGMLALDNMLYLAKVHQDTYIRIVLENSSREDKHECPFGRSAIELTKMLCEILQVGELPNEGRNDYHPMFFTHDRAFEELFGICIQLLNKTWKEMRATAEDFNKVMQVVREQITRALPSKPNSLDQFKSKLRSLSYSEILRLRQSERMSQDDFQSPPIVELREKIQPEILELIKQQRLNRLCEGSSFRKIGNRRRQERFWYCRLALNHKVLHYGDLDDNPQGEVTFESLQEKIPVADIKAIVTGKDCPHMKEKSALKQNKEVLELAFSILYDPDETLNFIAPNKYEYCIWIDGLSALLGKDMSSELTKSDLDTLLSMEMKLRLLDLENIQIPEAPPPIPKEPSSYDFVYHYG", "length": 720 }, "evidence": [ { "id": "FB:FBgn0032409", "url": "https://alliancegenome.org/gene/FB:FBgn0032409#orthology", "database": "AGR" }, { "id": "SGD:S000003930", "url": "https://alliancegenome.org/gene/SGD:S000003930#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VKB2-1", "protein_name": "Ced-12", "gene_name": "Ced-12", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIPKKTTVKDSHIVKIAVEREDHIAQLINLDQRHPLASKIQEICNGWSISDHQNYALQFYEPTNRKYVTEKNRNEIKNGSVLQLQYSPSKTACDAMEVLLNGSPQEKALRLKELTSLSTDHTFALEFIKEKGLDTLIKMIEDGGQTNEDILKYSLASFVELMEHGTVSWEVPENSFVARNIEIVRNFQKYPTNCGESALSNLENIVMCSNKHVLVAEDIKLQDILRLLQDVNSPVMRQNAIALLNALFVKADEGRRRTIAQTISAKQFRLALIGNGLGTEMTHQLYVLQTLTLGLLEKRMRMKMNAQDQDAHEKIKELRRIAFDDNTNALNQNDDHIRRGGGSGAGNVNFSQYYKKLGFKCDINPAQDFIETPPGILALDCMVYFARNYTQQYAKIVRENSCRADEHECPFGRTSIELVKVLCDILRIGEPPAEQSGDFQPMFFTHDSPFEEFFCICVITLNRTWKDMRATAEDFSTTFSVVREQIQRTLKGRPENLDDFRNKIALLTYQQITTLRQQERTSKEECDSTASAIVKLKEKISPQILELIKQQRLSFLVEGTHFAKYLRGTRTKDKFWYARLSPNHKVIHYGDCDEKTIPTMEELPKKLPISEIKQLLEGKECPHMKETRIRKSAVNLAFSITFENMEHSTLDFVAPDESIFNYWTDGINALLGQPMVSKQKNEDFDTLLSMEIKLRLLDTEGVDISKDPPPIPEDPENYDFCFES", "length": 724 }, "evidence": [ { "id": "MGI:2679007", "url": "https://alliancegenome.org/gene/MGI:2679007#orthology", "database": "AGR" }, { "id": "HGNC:17289", "url": "https://alliancegenome.org/gene/HGNC:17289#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050309-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050309-39#orthology", "database": "AGR" }, { "id": "FB:FBgn0032409", "url": "https://alliancegenome.org/gene/FB:FBgn0032409#orthology", "database": "AGR" }, { "id": "RGD:1304734", "url": "https://alliancegenome.org/gene/RGD:1304734#orthology", "database": "AGR" }, { "id": "SGD:S000003930", "url": "https://alliancegenome.org/gene/SGD:S000003930#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4G1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1" } ], "pmid": "" }, { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4G1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4G1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1" } ], "pmid": "" }, { "name": "glomerulus development", "id": "GO:0032835", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032835", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4G1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1" } ], "pmid": "" }, { "name": "cell motility", "id": "GO:0048870", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048870", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4G1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1" } ], "pmid": "" }, { "name": "regulation of vasculogenesis", "id": "GO:2001212", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001212", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4G1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SH3 domain binding", "id": "GO:0017124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017124", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4G1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 163, "end_pos": 165, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z4G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1" }, { "id": "PS51335", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51335" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELMO", "eco_id": "ECO_0000259", "start_pos": 316, "end_pos": 486, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z4G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4G1" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 548, "end_pos": 667, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 163, "end_pos": 165 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 458, "end_pos": 460 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z4H1-1", "uniprot_ac": "A0A8M6Z4H1", "uniprot_id": "A0A8M6Z4H1_DANRE", "mass": { "chemical_mass": 51919.0, "monoisotopic_mass": 51919.0 }, "refseq": { "ac": "XP_017209731", "name": "olfactomedin-4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209731" }, "gene_names": [ { "name": "si:ch211-194m7.8", "type": "recommended", "evidence": [ { "id": "A0A8M6Z4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4H1" } ] }, { "name": "si:ch211-194m7.8", "type": "synonym", "evidence": [ { "id": "XP_017209731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209731" } ] } ], "protein_names": [ { "name": "Olfactomedin-4", "type": "synonym", "evidence": [ { "id": "A0A8M6Z4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4H1/entry#names_and_taxonomy" } ] }, { "name": "olfactomedin-4", "type": "synonym", "evidence": [ { "id": "XP_017209731", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209731" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017209731.1. 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"https://www.ncbi.nlm.nih.gov/gene/568857", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003112", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003112", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050605", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050605", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:568857", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568857", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEVNSTM", "url": "https://omabrowser.org/oma/group/CEVNSTM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z4H1", "url": "https://www.orthodb.org/?gene=A0A8M6Z4H1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23192:SF31", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23192:SF31", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02191", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02191", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017209731", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209731", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4H1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4H1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4H1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120709-95", "url": "https://zfin.org/ZDB-GENE-120709-95", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLSFLLLLTVTLSVESQKIPGEQKNDSCVCKLSSSIWAFPAVRFEKAMKQLQTCEENLTEFQKRIRDVELPKMKLTLKNIKSRQKRSDFANRNDLYKSLHLQELILELEEIYNTATEVHKKNPSKTTNDLLKELTKARKDVQNMYKSNVFNLETMQKRLRDLNNRVQSCKTIPEDFRSTCHQRIMSRISSPVVTKLNSISKSYISGAWGRDAKPNSKERYWEHCLVSGHKYGNTFRMYNSYEDFMGSKNYKDEYVASSYSHTNAVQGSGTILYDNTVFYQCYGKAEICSFNITTQKTKRMKLDDAGIENTFPFCYYSCRDWTDIDLEADRDAVWVIYATMENHGNIVLSRLDPVELNITHTFKTHLFKRSVSSTFMVCGVLYATRFVNTYQEEVFYAFDTTTGQEINSLSLPFEKVSAGIANLNYNPVDRKLYMYNDGYLLAYNTFN", "length": 447, "header": "tr|A0A8M6Z4H1-1|A0A8M6Z4H1_DANRE Isoform 1 of Olfactomedin-4 OS=Danio rerio OX=7955 GN=si:ch211-194m7.8 PE=1 SV=1 CANONICAL=A0A8M6Z4H1-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z4H1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4H1/entry#A0A8M6Z4H1-1", "sequence": { "sequence": "MLSFLLLLTVTLSVESQKIPGEQKNDSCVCKLSSSIWAFPAVRFEKAMKQLQTCEENLTEFQKRIRDVELPKMKLTLKNIKSRQKRSDFANRNDLYKSLHLQELILELEEIYNTATEVHKKNPSKTTNDLLKELTKARKDVQNMYKSNVFNLETMQKRLRDLNNRVQSCKTIPEDFRSTCHQRIMSRISSPVVTKLNSISKSYISGAWGRDAKPNSKERYWEHCLVSGHKYGNTFRMYNSYEDFMGSKNYKDEYVASSYSHTNAVQGSGTILYDNTVFYQCYGKAEICSFNITTQKTKRMKLDDAGIENTFPFCYYSCRDWTDIDLEADRDAVWVIYATMENHGNIVLSRLDPVELNITHTFKTHLFKRSVSSTFMVCGVLYATRFVNTYQEEVFYAFDTTTGQEINSLSLPFEKVSAGIANLNYNPVDRKLYMYNDGYLLAYNTFN", "length": 447, "header": "tr|A0A8M6Z4H1-1|A0A8M6Z4H1_DANRE Isoform 1 of Olfactomedin-4 OS=Danio rerio OX=7955 GN=si:ch211-194m7.8 PE=1 SV=1 CANONICAL=A0A8M6Z4H1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:568857", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568857", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1RRZ8-1", "protein_name": "Olfactomedin", "gene_name": "si:ch211-194m7.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFFNLLLLTVIVTVEAQRVPGLQKTDSCLCKINSSIWTFPAVQFMEVTRQVQVCEEILDEFEEKVINTNAELPMMEATLQNITSRLKPFDYLYKSGLYSALYLRQLNQELEEIHRSVSETHMQNPKKETRTLLRELNKTKKDAQKMYKDDFFNLESMKNRLRDLNNRAQTSKTMPTDFRSSCHQRIMTRISSPVVTKLNSISKSYISGAWGRDALLTDKERYWEHCLVSGHKDGHTIRMYNSYEDFMANRNYKDEQIAPSYSSKNAVRGSGTILYNNTVYYQCYDKAEICSFDITSQSTKRMKLDGAGIDNKFPFCYYSCRDWTDIDLEADRDAVWVIYATEENHGNIILSRLDPVELNITHTFKTHLFKRSVSSTFMVCGVLYATRYVNTYQEEVFYAFDTTTGQEINSLSLPFEKVAAGIANLNYNPVDRRLYMYNDGYLLAYNTFN", "length": 449 }, "evidence": [ { "id": "RGD:1310717", "url": "https://alliancegenome.org/gene/RGD:1310717#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YVZ3-1", "protein_name": "Olfactomedin-4", "gene_name": "si:ch211-194m7.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSPNQIFILLIIIPPAFFQSARGKDCVCDLKNSEPAFPDHKLTKVEATAKQCIRTITSEKMMEMDILVLGLQQRITQLDENMAKLENEDNSKLYGAVSMRIIDLEIAEIQNLLDKLNATTKGYNHLSIQTADQLEDMKDTMEDLEKFDNMQVVKKDRENQRYKKQLEECKDELEATLPPPTVLPGRCGLGRLVKVAGPRTYSLTVYSTSYTYGAWGRDVNPAPGDENKYWLVVLYTSNVYGNFIRQYSTLSTFLLNIGPIDTYIAGSNPTTNTIQGPNMVMYANALYYNCYNSYSVCQFNMTTKSVNTVALPSDTGYSSKFPFAHLGHTYGYTDMDFVTEESGVYVIYATTSNFGNVVISKVETSTPPVLGQTWSTSLHKRTVTNTFMVCGVLYATRYLDKETEEIFYSYDTKTNKERYDLRIHIKKMQANIQFLNYDPRDHLLYAYSDAYIVTYELVFQ", "length": 460 }, "evidence": [ { "id": "RGD:1310717", "url": "https://alliancegenome.org/gene/RGD:1310717#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2M7-1", "protein_name": "Olfactomedin-4", "gene_name": "olfm4.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMMMMKILLLSVFMLAAPAQAWLSLEDWGSGSVDGSIGDLGQCVCNVFLPDTSFPADRMEQMQSSSKQLAVEVQIHISKLSSLKVELVVLLESLSNLTARLEVLESGPDKYIKLEFELLRVELREFEALVTQIKTSLNSSSSAFDSLYAEIHSMRIIVDQLESYDRSNLEVIRHEFTKLQRKLKKCQEDQQDITNAPIGSCKHAGILKIGKPVVSQLNADLNGAFKYGGWGKDSKPLSGSESMYWYSGSSDTLVSKISQYSAYYTLITRQSFKAHLLYVDRQYDWRGAGNNYVVRENNLYYQYRSPFAMAKFNMTSAKVETKVVPKASTQFSYHYSINQNLDFAADESGLWVTYATADSNGTLVLGKINEQSFTVEEVWQTSIFKQSVTNAFMICGVLYATRSVDTHTEEIFYTYDTTKNQESHVSIRFEKFQDFYVYLDYNPADQKLYMFNNGYYVTYNLKFKVV", "length": 466 }, "evidence": [ { "id": "RGD:1310717", "url": "https://alliancegenome.org/gene/RGD:1310717#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z8Z4-1", "protein_name": "Olfactomedin 5", "gene_name": "Olfm5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSDPALMASFLLLLPLVLPGQPQLVRSVLSSMDESGTFQCVVHLPNSSIFLQQLEQLQSTLQELIGKYEQELSRVKEYAHVIEDQDSQTLELSHMLEARNPGVTLSQYDNPAFNLLRLELEGAQELAAQLKANGGVSGASDLLYELQNRVTNASLTLKLLVDSDRQSFHALQEEVDILEGQLSECEREKEQEQSSRHPGPPLAPGSCAHGGLQKVSRPLVVKLNWRGLSYKAGAWGRDSAPNPVSSLYWVAPLRADGRYFDYYRLHKSYDDLVLLKHYEQWKMGYGDGSGNTVYKNFMYFNYYGTRYMAKVDLSSNTLVLRRPLPGATYNNRFSYACVPWTDIDFAGDEKGLWVFYATEESKGNLVVSLLNDSTLEVEQTWYTSQYKPALSGAFMACGVLYALRSLSTRQEEIFYAYDTTTGQEHHLSILLDKMLETLHGINYCPWDHRLYVYNDGFLINYDLTFLTLKLPSSPMKRPSGAPAPFKPIKSNQPSRIRDSMTHQGPIRNMFSPSPLEGRFP", "length": 521 }, "evidence": [ { "id": "RGD:1310717", "url": "https://alliancegenome.org/gene/RGD:1310717#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120709-95", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120709-95#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4H1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4H1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4H1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4H1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 57, "end_pos": 59, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z4H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4H1" }, { "id": "PS51132", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51132" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Olfactomedin-like", "eco_id": "ECO_0000259", "start_pos": 179, "end_pos": 447, "start_aa": "Thr", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 25, "end_pos": 27 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z4R4-1", "uniprot_ac": "A0A8M6Z4R4", "uniprot_id": "A0A8M6Z4R4_DANRE", "mass": { "chemical_mass": 37900.0, "monoisotopic_mass": 37900.0 }, "refseq": { "ac": "XP_017209933", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209933" }, "gene_names": [ { "name": "LOC108182290", "type": "recommended", "evidence": [ { "id": "A0A8M6Z4R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4" } ] }, { "name": "LOC108182290", "type": "synonym", "evidence": [ { "id": "XP_017209933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209933" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M6Z4R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017209933", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209933" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017209933.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017209933", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209933" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108182290", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z4R4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z4R4", "database": "AlphaFoldDB", "categories": [] }, { "id": "108182290", "url": "https://www.ncbi.nlm.nih.gov/gene/108182290", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108182290", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108182290", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z4R4", "url": "https://www.orthodb.org/?gene=A0A8M6Z4R4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45993", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45993", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45993:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45993:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017209933", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209933", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFIKEESEDLKIEETFTVKQEDLQEQTDLTEESEGSKEEEHHVKIEDKTHLQTDGILKRRDKNRFTCTQCGKSFGGNGNLKIHMIIHTGKKPFTCTQCGKSFSQSSHLNDHMMIHTGEKPFTCTQCGKSFIRLSLLNQHMMIHTGEKPFTCTQCGKSFRQSSYLNEHMMIHTGEKPFTCTQCWKSFSRSSDLNLHMRIHTGEKPFTCTQCGKSFSCSSLNKHMRIHTGEKPFTCTQCGKSFSCSSYLNQHMRIHTGEKPFTCTKCGKSFNCSSHLNRHMRNHTGEKLFTCTQCGKSFRQPSLLYLHMISHNGEKPTASVWDEFQQLLRP", "length": 330, "header": "tr|A0A8M6Z4R4-1|A0A8M6Z4R4_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC108182290 PE=4 SV=2 CANONICAL=A0A8M6Z4R4-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z4R4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4/entry#A0A8M6Z4R4-1", "sequence": { "sequence": "MAFIKEESEDLKIEETFTVKQEDLQEQTDLTEESEGSKEEEHHVKIEDKTHLQTDGILKRRDKNRFTCTQCGKSFGGNGNLKIHMIIHTGKKPFTCTQCGKSFSQSSHLNDHMMIHTGEKPFTCTQCGKSFIRLSLLNQHMMIHTGEKPFTCTQCGKSFRQSSYLNEHMMIHTGEKPFTCTQCWKSFSRSSDLNLHMRIHTGEKPFTCTQCGKSFSCSSLNKHMRIHTGEKPFTCTQCGKSFSCSSYLNQHMRIHTGEKPFTCTKCGKSFNCSSHLNRHMRNHTGEKLFTCTQCGKSFRQPSLLYLHMISHNGEKPTASVWDEFQQLLRP", "length": 330, "header": "tr|A0A8M6Z4R4-1|A0A8M6Z4R4_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC108182290 PE=4 SV=2 CANONICAL=A0A8M6Z4R4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 317, "start_aa": "Thr", "end_pos": 317, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr317", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:108182290", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108182290", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z4R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4R4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 93, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 317 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 271, "end_pos": 273 }, { "start_pos": 282, "end_pos": 284 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z4U9-1", "uniprot_ac": "A0A8M6Z4U9", "uniprot_id": "A0A8M6Z4U9_DANRE", "mass": { "chemical_mass": 230203.0, "monoisotopic_mass": 230203.0 }, "refseq": { "ac": "XP_017209463", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209463" }, "gene_names": [ { "name": "LOC108181536", "type": "recommended", "evidence": [ { "id": "A0A8M6Z4U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4U9" } ] }, { "name": "LOC108181536", "type": "synonym", "evidence": [ { "id": "XP_017209463", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209463" } ] } ], "protein_names": [ { "name": "Integrase catalytic domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M6Z4U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4U9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017209463", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209463" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017209463.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017209463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209463" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4U9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108181536", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4U9", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z4U9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z4U9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01644", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01644", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "108181536", "url": "https://www.ncbi.nlm.nih.gov/gene/108181536", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108181536", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108181536", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR47331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47331:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47331:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03564", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03564", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017209463", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209463", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z4U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4U9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATQAVGKSLEQLKAKRTVEKRAFTRLANTIFKTCKNMTEMDLQDSLNKLTIQAEKVMEVNDDLEAGMIAEIEANLDTDQSAELTEQQKDDLEKTASDCELKLDEVKVLLHETLWTRYGDVELSTALQVAEAESDRVEAVDPTGNHEAYDFMLSHLQNLIKNAKEMYNKWQRCIPSGDERDFSQRQRGLEANITRLVARKADFMQARQAEEARNIAHVPVISTYPIATIKLKPATLPKFSGSKRDFHRWKKDWEALQKQGEPTGSKEVKKVQLLDSLEEKIVRELRLTTYNSADDIFRVLENRYGNKTAIAIEIVEDLQKIPPIRSHQPRKIVELIQEVEMALGDLSDLGNTGAINNPLVTKSIEGKLPESLKKEWLIHVSAQQSAVTPDNRFDYLLDFLKKQENIYEQLEQLRLEEPNRKDVRNESKWAKTKSTKSNTDQAGCVVCGDAKHKWKLYFCKQFRASKLVDKKAAVSALGACKKCLEVHEQYSFCKRNYLCKSQDCEDEGVPEHHYYLCPNAKREEKRADQKKSKLCPKTEKCVKDYTRDQQDFLSRLSPELAQQCRNVFSNTTARVFNVTKEKPGLLAQSGLLELPVIMMLLNVTANAGQKIGTLIDLASDTNYITHSAADRLNLKGEKITLVIHGVGGMKVRMKTKRYLLKIRVRTSQGTFKSHQLACYGLESIAEINNTVQPNQLKKLFPDIPLAELARPKVVDLLISHREGQLAPQRIRIVGDLVLWDGPLGKTIGGTHPELFEDVTVSAYRSKTHFARSMRLAAVKYEEVTEYSPPNKPLARLHESSVSTSTRDFLEWWKWDSIGAACVPKCGGCRCGNCQPGGKEMSLAEERELELVKEGLTYVMEDKHSNEPHWHAKYPWIQDPTSLPDNRRAVEATFLRTEKQLAKDPQWKAAYSAQVKDMLDRGAAVKLPESSIANWAGPVWYVSHLIAPNPHSVTTPVRLVWNSSQRFRGVSMNDLLIKGPDVLNQIRAVLLRFRSGVYAALGDIKKMYNSVWLEDQEVHLHRFLWRDTENEELGEYAITRVNIGDKPAGCIAQLAMRETANLPSFAHLKEERRVIQHDSYVDDILTSHNDLDQLQSIVANTELILKAGGFHLKPWVFSGQSGREKSDDKSCKIKEKVMVLPNQMHDDDNKALGLGYSVEEDKLYVMTSINFSKRKKKIRLGQNLTQEQVRAQTPNPLTRRELLSQVSGVYDPVGLVTPAKQKGAILVRRAFQEAKNTRLQVNETWDVALSDDLREDAIKLFEEYIQLGQIKFTRAITPPEFEGHPWAITFSDGSENTYGAVMYLRWDSKQGPVIRLVESKAKLTPLDQKGDAIKAEVCGAVFASRLRKYFEQHSRIQVERWFHLVDSQTVLGAIQRESYGYKTFFANRIGEIQGITKAQEWWWIPGPQNIADVITRGASPQNLVESSEWQNGPRFLSLPVDEWPVKSAKDLAITARESINELQKKAFAAVLTRSKTKQKEPTMESKPIESPNLVRAEQKRPPAGLAVLNLCDIKRFSDLSRLVKTIAWVWRAAKKFLGKKRTVNKPKWEAVLSLGTISVREREDALRDIFLAEQDGVTFPNTTKERLVVFKDPDSGLLVCGGRVQVFQDDQLSVPILPSNSWISTLLAQESHKESHGGLAETLLRMRRRAWVLKGRRIAQKVVDSCVQCRKNKAKKCQQIMGDLPLERTQPAAPFEFTAVDLFGPYHVKDDVKKRVLLKVWGVVFCCMSSRAIHTELVNSQSTEGFLLAFQRFAAIRGYPRKIFSDPGTNFIGARPVLQDLYQFLEGIDKSTLEETAVKHGTEWIWKIHPADSPHRNGAAEAAVRIIKRALQNCGGESALTYSEMHTALQIAANLANERPIDAREQTQEGCIQYVTPNSLLLGRASQSGDIKTFDFSSYPFKRLQAMQSLVNKFWERWSQLAGPNLFIRSKWHTTHRNVAIGDIVWIADQNALRGQFKLGRVISVNPDSKGVVRDVNIRTFPSYPVLITKPSKARANSSESKVGREKIPSTVLHRDVRRLVVLLPAEEQRSE", "length": 2031, "header": "tr|A0A8M6Z4U9-1|A0A8M6Z4U9_DANRE Isoform 1 of Integrase catalytic domain-containing protein OS=Danio rerio OX=7955 GN=LOC108181536 PE=4 SV=2 CANONICAL=A0A8M6Z4U9-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z4U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4U9/entry#A0A8M6Z4U9-1", "sequence": { "sequence": "MATQAVGKSLEQLKAKRTVEKRAFTRLANTIFKTCKNMTEMDLQDSLNKLTIQAEKVMEVNDDLEAGMIAEIEANLDTDQSAELTEQQKDDLEKTASDCELKLDEVKVLLHETLWTRYGDVELSTALQVAEAESDRVEAVDPTGNHEAYDFMLSHLQNLIKNAKEMYNKWQRCIPSGDERDFSQRQRGLEANITRLVARKADFMQARQAEEARNIAHVPVISTYPIATIKLKPATLPKFSGSKRDFHRWKKDWEALQKQGEPTGSKEVKKVQLLDSLEEKIVRELRLTTYNSADDIFRVLENRYGNKTAIAIEIVEDLQKIPPIRSHQPRKIVELIQEVEMALGDLSDLGNTGAINNPLVTKSIEGKLPESLKKEWLIHVSAQQSAVTPDNRFDYLLDFLKKQENIYEQLEQLRLEEPNRKDVRNESKWAKTKSTKSNTDQAGCVVCGDAKHKWKLYFCKQFRASKLVDKKAAVSALGACKKCLEVHEQYSFCKRNYLCKSQDCEDEGVPEHHYYLCPNAKREEKRADQKKSKLCPKTEKCVKDYTRDQQDFLSRLSPELAQQCRNVFSNTTARVFNVTKEKPGLLAQSGLLELPVIMMLLNVTANAGQKIGTLIDLASDTNYITHSAADRLNLKGEKITLVIHGVGGMKVRMKTKRYLLKIRVRTSQGTFKSHQLACYGLESIAEINNTVQPNQLKKLFPDIPLAELARPKVVDLLISHREGQLAPQRIRIVGDLVLWDGPLGKTIGGTHPELFEDVTVSAYRSKTHFARSMRLAAVKYEEVTEYSPPNKPLARLHESSVSTSTRDFLEWWKWDSIGAACVPKCGGCRCGNCQPGGKEMSLAEERELELVKEGLTYVMEDKHSNEPHWHAKYPWIQDPTSLPDNRRAVEATFLRTEKQLAKDPQWKAAYSAQVKDMLDRGAAVKLPESSIANWAGPVWYVSHLIAPNPHSVTTPVRLVWNSSQRFRGVSMNDLLIKGPDVLNQIRAVLLRFRSGVYAALGDIKKMYNSVWLEDQEVHLHRFLWRDTENEELGEYAITRVNIGDKPAGCIAQLAMRETANLPSFAHLKEERRVIQHDSYVDDILTSHNDLDQLQSIVANTELILKAGGFHLKPWVFSGQSGREKSDDKSCKIKEKVMVLPNQMHDDDNKALGLGYSVEEDKLYVMTSINFSKRKKKIRLGQNLTQEQVRAQTPNPLTRRELLSQVSGVYDPVGLVTPAKQKGAILVRRAFQEAKNTRLQVNETWDVALSDDLREDAIKLFEEYIQLGQIKFTRAITPPEFEGHPWAITFSDGSENTYGAVMYLRWDSKQGPVIRLVESKAKLTPLDQKGDAIKAEVCGAVFASRLRKYFEQHSRIQVERWFHLVDSQTVLGAIQRESYGYKTFFANRIGEIQGITKAQEWWWIPGPQNIADVITRGASPQNLVESSEWQNGPRFLSLPVDEWPVKSAKDLAITARESINELQKKAFAAVLTRSKTKQKEPTMESKPIESPNLVRAEQKRPPAGLAVLNLCDIKRFSDLSRLVKTIAWVWRAAKKFLGKKRTVNKPKWEAVLSLGTISVREREDALRDIFLAEQDGVTFPNTTKERLVVFKDPDSGLLVCGGRVQVFQDDQLSVPILPSNSWISTLLAQESHKESHGGLAETLLRMRRRAWVLKGRRIAQKVVDSCVQCRKNKAKKCQQIMGDLPLERTQPAAPFEFTAVDLFGPYHVKDDVKKRVLLKVWGVVFCCMSSRAIHTELVNSQSTEGFLLAFQRFAAIRGYPRKIFSDPGTNFIGARPVLQDLYQFLEGIDKSTLEETAVKHGTEWIWKIHPADSPHRNGAAEAAVRIIKRALQNCGGESALTYSEMHTALQIAANLANERPIDAREQTQEGCIQYVTPNSLLLGRASQSGDIKTFDFSSYPFKRLQAMQSLVNKFWERWSQLAGPNLFIRSKWHTTHRNVAIGDIVWIADQNALRGQFKLGRVISVNPDSKGVVRDVNIRTFPSYPVLITKPSKARANSSESKVGREKIPSTVLHRDVRRLVVLLPAEEQRSE", "length": 2031, "header": "tr|A0A8M6Z4U9-1|A0A8M6Z4U9_DANRE Isoform 1 of Integrase catalytic domain-containing protein OS=Danio rerio OX=7955 GN=LOC108181536 PE=4 SV=2 CANONICAL=A0A8M6Z4U9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1276, "start_aa": "Thr", "end_pos": 1276, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1276", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:108181536", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108181536", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4U9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z4U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4U9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1169, "end_pos": 1171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1182, "end_pos": 1184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1241, "end_pos": 1243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1580, "end_pos": 1582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1996, "end_pos": 1998, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 602, "end_pos": 604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 688, "end_pos": 690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 961, "end_pos": 963, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z4U9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z4U9" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 1689, "end_pos": 1884, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1276 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1169, "end_pos": 1171 }, { "start_pos": 1182, "end_pos": 1184 }, { "start_pos": 1241, "end_pos": 1243 }, { "start_pos": 1580, "end_pos": 1582 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 1996, "end_pos": 1998 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 425, "end_pos": 427 }, { "start_pos": 570, "end_pos": 572 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 602, "end_pos": 604 }, { "start_pos": 688, "end_pos": 690 }, { "start_pos": 961, "end_pos": 963 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z546-1", "uniprot_ac": "A0A8M6Z546", "uniprot_id": "A0A8M6Z546_DANRE", "mass": { "chemical_mass": 53595.0, "monoisotopic_mass": 53595.0 }, "refseq": { "ac": "XP_017209757", "name": "coronin-2B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209757" }, "gene_names": [ { "name": "coro2bb", "type": "recommended", "evidence": [ { "id": "A0A8M6Z546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z546" } ] }, { "name": "coro2bb", "type": "synonym", "evidence": [ { "id": "XP_017209757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209757" } ] } ], "protein_names": [ { "name": "Coronin", "type": "recommended", "evidence": [ { "id": "A0A8M6Z546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z546/entry#names_and_taxonomy" } ] }, { "name": "coronin-2B", "type": "synonym", "evidence": [ { "id": "XP_017209757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209757" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017209757.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017209757", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209757" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z546", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z546" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "coro2bb", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z546", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-071009-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071009-5", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z546", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z546", "database": "AlphaFoldDB", "categories": [] }, { "id": "796974", "url": "https://www.ncbi.nlm.nih.gov/gene/796974", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR10856", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10856", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10856:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10856:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08953", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08953", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017209757", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209757", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z546", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z546", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z546-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z546-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-071009-5", "url": "https://zfin.org/ZDB-GENE-071009-5", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSWSSAYRSSKFRHVYGKAGSREQCYEGIPITHSVHDNQFCAVNPKFLAVVTESAGGGAFIVIPLHKPGRVDPHYPRVCGHQGSVMDIKWSPFMDNIIASSSEDCTVRIWQIPDNGLRRNLTEALMILIGHSRRVGLIEWHPTCSGILFSAGYDCKILMWNLEEGVAVKMIDSHPDVVLCMSFNTDGSLLATSCKDKKLRIIDPRSGKVLQESCCKSLRVNRVVFLGNLRRVFTTGVSRWNSRQIALWDQDDLSCPLLEEEIDGLAGALFPYYDPDTHMLYLAGKGDGNIRYYEVGAEKPFLQFLTEFRSAAPQKSLCVMPKRGVDVSECEIFRFYKLVTFRGLVEPVSMIVPRRSEAYQEDIFPMTAGAESALSAAEWLSGIDRGPVLISLKEAYKRPNPVSLRASRRDRRMIKGIDLLENISMNTDRELLTTVYRQQEELRKLKEELREKEERIQTLELELNNLRNTHTH", "length": 472, "header": "tr|A0A8M6Z546-1|A0A8M6Z546_DANRE Isoform 1 of Coronin OS=Danio rerio OX=7955 GN=coro2bb PE=3 SV=2 CANONICAL=A0A8M6Z546-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z546-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z546/entry#A0A8M6Z546-1", "sequence": { "sequence": "MSWSSAYRSSKFRHVYGKAGSREQCYEGIPITHSVHDNQFCAVNPKFLAVVTESAGGGAFIVIPLHKPGRVDPHYPRVCGHQGSVMDIKWSPFMDNIIASSSEDCTVRIWQIPDNGLRRNLTEALMILIGHSRRVGLIEWHPTCSGILFSAGYDCKILMWNLEEGVAVKMIDSHPDVVLCMSFNTDGSLLATSCKDKKLRIIDPRSGKVLQESCCKSLRVNRVVFLGNLRRVFTTGVSRWNSRQIALWDQDDLSCPLLEEEIDGLAGALFPYYDPDTHMLYLAGKGDGNIRYYEVGAEKPFLQFLTEFRSAAPQKSLCVMPKRGVDVSECEIFRFYKLVTFRGLVEPVSMIVPRRSEAYQEDIFPMTAGAESALSAAEWLSGIDRGPVLISLKEAYKRPNPVSLRASRRDRRMIKGIDLLENISMNTDRELLTTVYRQQEELRKLKEELREKEERIQTLELELNNLRNTHTH", "length": 472, "header": "tr|A0A8M6Z546-1|A0A8M6Z546_DANRE Isoform 1 of Coronin OS=Danio rerio OX=7955 GN=coro2bb PE=3 SV=2 CANONICAL=A0A8M6Z546-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KEJ7-1", "protein_name": "Coronin", "gene_name": "coro", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSFRVVRSSKFRHVYGQALKREQCYDNIRVSKSSWDSTFCAVNPKFLAIIVESAGGGAFIVLPHNKVGRIAADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDCVVKVWQIPDGGLSRTLTEPVVDLVFHQRRVGLVLWHPSALNVLLTAGSDNQVVIWNVGTGEILVHIDSHPDIVYSACFNWDGSKLVTTCKDKKIRIYDPRTAELESEAMCHEGSKATRAIFLRHGLIFTTGFNRSSERQYSLRAPDALNEPIVMVELDTSNGVMFPLYDADTNMIYLCGKGDSVIRYFEVTPEPPFVHYINTFQTTEPQRGIGLMPKRGCDVTTCEVAKFYRMNNNGLCQVISMTVPRKSDLFQEDLYPDTLAEDAAITAEEWIDGKDADPITFSLKDRVSIVQGGYVSSSVNKSLPAKKAGNILNKPRGDSASSGATSSSAGGGNFASGNNNEASEGGPPAAVLSEKDLRTIQDEIRKLKAIIVKQENRIRALEAKEDARNKNGSDAAPASAGAATSDGKASESANDHASTSAGTSKDED", "length": 535 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A0G2QC56-1", "protein_name": "Coronin", "gene_name": "Coro2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWNGNSKLRPSPPLLKPNQMSWHPQYRSSKFRHVYGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDIKWNPFDDFEIASCSEDATIKIWNIPKQLLTRNLTTYRKELMGHARRVGLVEWHPTTANILFSAGYDYKVMVWNLDTKDSVISGPVRTINCHQDVILSMSFNTNGSLLATTCKDRKIRIVDPRLGIVLQEASYKGHRANKVLFLGNLKKLLSTGTSRWNNRQMALWDQDNLSVPLTEEDLDGSSGVLFPFFDSDTSMLYIVGKGDGNIRYYEVSTEKPHLTYLTEYRSYNPQKGIGIMPKRGLDVSSCEIFRFYKLITTKSLIEPVSMIVPRRSESYQEDIYPPTAAAQPSLTAHEWLSGMNRGPIMMSLRPGSELLDPQALPPERLLSNSVVQVSPQPLEPVKQPAEDGDQAPFSLLEEKVTKWTTEHQLEEKSWLTNGFDIFECPPPKTENELLQMFYRQQEEIRRLRELLIQREVQTKQLELEIKNLRMVLGQF", "length": 543 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M6YV26-1", "protein_name": "Coronin", "gene_name": "coro6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRSIVRQSKFRHVFGQAVKADQAYDDIRVSKVTWDSSFCAVNPKFLAVIVESSGGGAFLVMPLSKMGRVDKNYPLVVGHSGPVLDIDWCPHNDNILASCSEDTTAMVWQIPDHTPSRPISEPIVVLEGHSKRVGIIKWHPTARNILLTAGSDNLIIIWNVGTGEALITMDDHPDLIYSVGWNYNGSLFCTTCKDRRLRVCDPRKNEVVAERLSPHEGIRPMRAIFTREGNIFTTGFTRMSQRELGLWDPTNFEEPIALLELDTSNGVLLPFYDPDTNIVYLSGKGDSSIRYFEITEEPPYVHYISTFSSKEPQRGMGFMPKRGVDVSKCEIARLYKLHERKCEPIMMTVPRKSDLFQDDLFPDTAGPDPAVEPEEWMDGRDADPILVSMRDGYVPPKSRELKVSKKNVLDSRPATRRSMSAVDGSSLPPQLLEKLIEEIQNLKATVLSQEKRICDLENKLSKYTNGTV", "length": 469 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QEN6-1", "protein_name": "Coronin", "gene_name": "coro1cb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGQTQDKELQNEDVLTVGDYEILSESEEEAHSNSPEENFIQLDTSKLKIYPSQQPTRLNDNNTEPSFKRGGKKISNSYDTDVLQNARTPNPQLSLAGRPRASEFKTALSDATTTNISATEDQQRPDKADRMTNKTHLKDTPNMLESSCQGDTRDDAVSVVKNERRTMSERYNGMLEAVRKTSGEIHRKFSLQSEKDKLLESHPFQNVGDSERKDKGELQTLCRDIGKSNDKDSFGTVWPTESTDADGFEYLDRADSLHPVIVAKSPSVAGLHSYSGHASNQDNLQVDKNITPDTLMCILKEPNDTPKTHFTVTPKENLRKDQRNPTFHSPLLGKEETALPEWGETEGKDKILHTPFGESSLLRSKLTTLDSFDSDTVIECRNADTALVQLRIEEDFEQKALSTFHPDLSQSNAVFHTEKKNCDKGAFAVMEKHSTVLSSESLTESSAKKVCVSNAPHPAKNGLWGTDAPCVKRDSESVYPKAVQARSTEWRKDCDGPPNRRRNTSPLFELSGGNGKIQDVRLGKGVCDPKIYMLDDSNTEVKEILSNGKCLDQMIVNQFNSFSHSDLDATRVAQKASLQREKEPLYFTAVITPTCQIYTFPDQEDSQFYVPHSQIQNMMPDISAEDNQTDKKAKIKGPPPPVPKKPKNPFKKAAHLKESASHSVDEPREYSDLLLKNIKMGRRQAALQSVEDFSTHASCLDMLPYYMDSPSYMCMSVEPENADIPRYYLVPYDEIAPDYDNLIETADDEELKEMDMSQLRPILKKKAKRKGPPPPIPKKPQNPFVKTDTEQIRASKDSEFENVDLPLEYGRRDSESFMMDVEDEEDCKPTAALTRHLQAACSASEENDLSRFRPVSELIRDSNKIHEKVIHHSRTNIMEARPDVTAGCQNLKVSQMKQAFDVQTSSHKMERRSSPKKEMIRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSAFCAVNPKFVAIIVEASGGGAFLVLPLQKTGRIDKAYPTVCGHTGPVLDIDWCPHNDHVIASGSEDCTVMVWQIPENGLTSALSEPVVVLEGHSKRVGIVTWHPTARNVLLSAGCDNLIIIWNVGTGEALINLEDMHPDVIFSVCWSRNGSLICTACKDKKVRVIDPRKGKITAEKDKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMEEPISVHEMDTSNGVLLPFYDPDTNVVYLCGKGDSSIRYFEITDEAPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPDPVLEAEEWFEGKNGEPILISLKHGYVPGKNRDLKVVKKNVLDNKATKKVEEPTTPQKPASPQLTRKNEVKLEELLREVKSLRDLVTLQDRRIAKLEEQVSKVAI", "length": 1392 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TAY8-1", "protein_name": "Coronin", "gene_name": "coro2ba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTVTKMSWRPTYRSSKFRNVYGKVANREHCFEGIPITKNVHDNHFCAVNAKFLAIVTESAGGGSFVVIPVTQFGRIDPHYPKVCGHQGNVLDIKWNPFHDNIIASCSEDSSVRIWEIPDSGLTRSLTESVLELYGHSRRVGLIEWHPTTSGILFSAGYDYKILIWNLEIGEPVKMIDCHSDVILCMSFNTEGSLLATSCKDKKLRVIEPRSGRVLQEANFKNHKVNRVVFLGNIKRLLTTGVSRWNTRQIALWDQEDLSMPIIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEVTLEKPYLQYLMEFRSPAPQKGLGVMPKHGLDVGACEVFRFYKLVTLKGLIEPISMIVPRRSETYQEDIYPMTPGTEPALSADEWLSGINRGPVLMSLKEGYNRPNKLVFKAPVKEKKGGVVNGIDLLENVPPRTENELLRMFFRQQEELRRLKDELTQKDIKIRQLELELNNIRNSPNINNNNNNSNGSSI", "length": 491 }, "evidence": [ { "id": "MGI:2444283", "url": "https://alliancegenome.org/gene/MGI:2444283#orthology", "database": "AGR" }, { "id": "HGNC:2256", "url": "https://alliancegenome.org/gene/HGNC:2256#orthology", "database": "AGR" }, { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58IMS5-1", "protein_name": "Coronin", "gene_name": "coro2ab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQHSFRASPFHHVIGKAAVKGRSYHGLSITRSVQDNHFCAVNPRFIAVVTECTGGGAFIVISVRHTGRVSPLHARVCGHSARVLDVKWDPFNDLRIASCSEDCTVKVWNIPPSGLKADLMLPSKDLLAHSRRVSLIEWHPTARDLLLSSAYDCKVFMWRLDSSDVPVIVINTHCELVLCLSFNADGSLLATACKDKKIRIIEPRTGRVLQESRWASHKVSRILFLWDLKMLLSTGHSCWNQRQFVLWDLEDLSEPLLEEDLDGGSGVIFPFYDADTHMLYLAGKGDGNIRYYAVSAVKPYVHFLSEYQSSSPQSGLGVMPKRGLNIRVCEVFRFYRLLTVKDLLEPLSFCVPRKQSEGFPEDIYPMTAANEPAMTANEWLMGQNKGPLLMSLRPKSEWFDPCLTETEPAANQNVEQPPPDLLADLRDWTDDDTQSQNWTSFSVSGAEACAPETEVAVPIESLIYPEEEEEEDCKPGSADRKRPQKILPAVQLLCFSMSRLPMSLCGFR", "length": 509 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B0R0D7-1", "protein_name": "Coronin-1C-A", "gene_name": "coro1ca", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFKRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSAFCAVNPKFVALIVEASGGGAFMVLPLHKTGRIDKAYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLVTSMSEPVVVLEGHSKRVGVVTWHPTARNVLLSAGCDNMIIIWNVGTGESMITLEDHHPDIIYSICWNRNGSLICTACKDKKIRVIDPRKEEIIAEKDKAHEGARPMRAIFLSDGKVFTTGFSRMSERQLALWDPENIDEPVAVHEMDTSNGVLLPFYDPDTNVVYLCGKGDSSIRYFEITDEAPFVHYLNTFTTKEPQRGMGYMPKRGLDVNKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPDAPLEAEEWFEGKNGDPVLISLKHGYIPGKNRDLKVVKKNILDNKMSKNTENTTPAHKTATSTPSIKSEAKLEEVLKEIKSLRELVSSQEKRIGKLEEQLSKMDI", "length": 474 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LMV9-1", "protein_name": "Coronin", "gene_name": "Coro2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVTKMSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPMIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGVNRDPVLMSLKEGYKKSSKVVFKAPIREKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRLRQLQLELKNLRNNPKNC", "length": 480 }, "evidence": [ { "id": "MGI:2444283", "url": "https://alliancegenome.org/gene/MGI:2444283#orthology", "database": "AGR" }, { "id": "HGNC:2256", "url": "https://alliancegenome.org/gene/HGNC:2256#orthology", "database": "AGR" }, { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QR96-1", "protein_name": "Coronin", "gene_name": "coro2aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTITKMTWRPQYRSSKYRHVFGKPATKENCYDGVPITRSVHDNQLCAANPRFIAVITECAGGGSFLVLPVHHTGKVDPHHPKVSGHRGNVLDIKWNHFNDFCIASCSEDATVKIWEIPEHGVLKTITVPWKELQGHSRRVGLIEWHPTANNIIFSTGYDYQVMVWKLDVPEQVIKNPVRSISVHSDVVLSMSFNTDGSKLATSCKDKKIRVIDPRTGTILQETNCKSHKASKVLFLGNLKMLLSTGNSRWNHRQIALWDQEDLSQPSYSEDLDGSSGVLFPFYDPDTHMLYIAGKGDGNIRYYEISPEKPYVHYLTEYRSHLPQKGMGVMPKRGLDVCSCEIFRFYKLVTIKSLIEPLSMIVPRRSESYQEDIYPMTAGNKPAMTANEWISGLDKGPVMMSLRPGSKVDTYVELGLKKSPMESTEMHNSRSQPGLSQLIQRLETKDGNGRKESHPTLLLPSTEENGSSASHVSNGQLDSPHCSPPKTENELRQMFYKQQEEIRKMRELLNQKDVRIKQLELEIKNVRNSQAPL", "length": 533 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3V624-1", "protein_name": "Coronin", "gene_name": "Coro1c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRRQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPAANKKSDLICAPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQLAKMAA", "length": 474 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O89046-1", "protein_name": "Coronin-1B", "gene_name": "Coro1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFMVLPLNKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCTACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTAGFSRMSERQLALWDPENFEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPDAALEAEDWVSGQDADPILISLREAYVPSKQRDLKVSRRNVLSDSKPAGYSRSGVSTATAITDIPSGNLAGSGEAGKLEEVMHGLRALRVLVKEQGERISRLEEHLGRMENGDT", "length": 484 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O89053-1", "protein_name": "Coronin-1A", "gene_name": "Coro1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFMALICEASGGGAFLVLPLGKTGRVDKNVPLVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLVLPLREPVITLEGHTKRVGIVAWHPTAQNVLLSAGCDNVILVWDVGTGAAVLTLGPDVHPDTIYSVDWSRDGALICTSCRDKRVRVIEPRKGTVVAEKDRPHEGTRPVHAVFVSEGKILTTGFSRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERKCEPIAMTVPRKSDLFQEDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDSARRRATPEPSGTPSSDTVSRLEEDVRNLNAIVQKLQERLDRLEETVQAK", "length": 461 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P31146-1", "protein_name": "Coronin-1A", "gene_name": "CORO1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFVALICEASGGGAFLVLPLGKTGRVDKNAPTVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLMLPLREPVVTLEGHTKRVGIVAWHTTAQNVLLSAGCDNVIMVWDVGTGAAMLTLGPEVHPDTIYSVDWSRDGGLICTSCRDKRVRIIEPRKGTVVAEKDRPHEGTRPVRAVFVSEGKILTTGFSRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERRCEPIAMTVPRKSDLFQEDLYPPTAGPDPALTAEEWLGGRDAGPLLISLKDGYVPPKSRELRVNRGLDTGRRRAAPEASGTPSSDAVSRLEEEMRKLQATVQELQKRLDRLEETVQAK", "length": 461 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q06440-1", "protein_name": "Coronin-like protein", "gene_name": "CRN1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSGKFVRASKYRHVFGQAAKKELQYEKLKVTNNAWDSNLLKTNGKFIAVNWNASGGGAFAVIPIEEVGKAPDQVPLFRGHTAQVLDTDFDPFNDHRIASGSDDSKIGIWDIPENYKFHDHVDEDGEPIDIKPVKFLTGHARKVGHVLYHPVAENVLASSSGDYTVKLWNVETGKDMITLKHPDMVTSMSFSYDGNYLATVARDKKLRVWNIREEKIVSEGPAHTGAKNQRVVWLGNSDRLATTGFSKLSDRQIGIWDAFNIEKGDLGGFYTVDQSSGILMPFYDEGNKILYLVGKGDGNIRYYEFQNDELFELSEFQSTEAQRGFAVAPKRMVNVKENEVLKGFKTVVDQRIEPVSFFVPRRSEEFQEDIYPDAPSNKPALTAEEWFSGKSVEGPILVSMRSIYDGSAPSFHEAKRPQQPTTQETALEEKKEQPKVEKPISESEKEVKQEAPKSPSPLKSASSSSTINHVLKEDNSINKLLKKSSDIDQVNNAEDPSRDTSGWEEADDEPAPIKIETPVTPTETKKDRTPKVEPSKELKPEPVSIATDRKQEQSLPQEEKSSEKTKSPEQEKSATPPSSITAAKTAITASSKEEPSAARTSPKSLGLKKSVEKLSTLVLQLEDVVDKLTKANLDKDERLLKLEQKIGELSK", "length": 651 }, "evidence": [ { "id": "MGI:2444283", "url": "https://alliancegenome.org/gene/MGI:2444283#orthology", "database": "AGR" }, { "id": "HGNC:2256", "url": "https://alliancegenome.org/gene/HGNC:2256#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071009-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071009-5#orthology", "database": "AGR" }, { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6QEF8-1", "protein_name": "Coronin-6", "gene_name": "CORO6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSSFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTAPVLDIDWCPHNDNVIASASDDTTIMVWQIPDYTPMRNITEPIITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDMHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKGQVVAEQARPHEGARPLRAVFTADGKLLSTGFSRMSERQLALWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLRDGYVPPKHRELRVTKRNILDVRPPSGPRRSQSASDAPLSQQHTLETLLEEIKALRERVQAQEQRITALENMLCELVDGTD", "length": 472 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BH44-1", "protein_name": "Coronin-2B", "gene_name": "Coro2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTVTKMSWRPQYRSSKFRNVYGKAANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPMIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKVVFKAPIREKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRLRQLQLELKNLRNNPKNC", "length": 480 }, "evidence": [ { "id": "MGI:2444283", "url": "https://alliancegenome.org/gene/MGI:2444283#orthology", "database": "AGR" }, { "id": "HGNC:2256", "url": "https://alliancegenome.org/gene/HGNC:2256#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071009-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071009-5#orthology", "database": "AGR" }, { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C0P5-1", "protein_name": "Coronin-2A", "gene_name": "Coro2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSWHPQYRSSKFRHVYGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDIKWNPFNDFEIASCSEDATIKIWNIPKQLLTRNLTTYRKELIGHARRVGLVEWHPTTANILFSAGYDYKVMVWNLDTKDSVIAGPVKTINCHQDVILSMSFNTNGSLLATTCKDRKIRIVDPRLGIVLQEASYKGHRANKVLFLGSLKKLLSTGTSRWNNRQMALWDQENLSVPLTEEDLDGSSGVLFPFFDSDTSMLYIVGKGDGNIRYYEVSMEKPHLTYLTEYRSYNPQKGIGIMPKRGLDVSSCEIFRFYKLITTKSLIEPVSMIVPRRSESYQEDIYPPTAAAQPSLTAHEWLSGMNRGPIMMSLRPGSELLDSQTLPPERPLSNSMVQVSPQPLEPMKQPAEDGDQAPFSLLEEKLAKWTAEHHLGEKSCLTNGFDVFECSPPKTENELLQMFYRQQEEIRRLRELLIQREVQTKQLELEIKNLRMALGQL", "length": 524 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91ZN1-1", "protein_name": "Coronin-1A", "gene_name": "Coro1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRQVVRSSKFRHVFGQPAKADQCYEDVRVSQTTWDSGFCAVNPKFMALICEASGGGAFLVLPLGKTGRVDKNVPLVCGHTAPVLDIAWCPHNDNVIASGSEDCTVMVWEIPDGGLVLPLREPVVTLEGHTKRVGIVAWHPTAQNVLLSAGCDNVILVWDVGTGAAVLTLGPDVHPDTIYSVDWSRDGALICTSCRDKRVRVIEPRKGTVVAEKERPHEGTRPVHAVFVSEGKILTTGFSRMSERQVALWDTKHLEEPLSLQELDTSSGVLLPFFDPDTNIVYLCGKGDSSIRYFEITSEAPFLHYLSMFSSKESQRGMGYMPKRGLEVNKCEIARFYKLHERKCEPIAMTVPRKSDLFQEDLYPPTAGPDPALTAEEWLSGRDAGPLLISLKDGYVPPKSRELRVNRGLDSARRRATPEPSSTLSSDTVSRLEEDVRNLNAIVQKLQERLDRLEETVQAK", "length": 461 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q920J3-1", "protein_name": "Coronin-6", "gene_name": "Coro6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTGPVLDIDWCPHNDNVIASASDDTTVMVWQIPDYTPVRNITEPVITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKSQVVAERFAAHEGMRPMRAVFTRLGHIFTTGFTRMSQRELGLWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITDEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLKEGYVPPKHREFRVTKRNILDVRPPASPRRSQSASEAPLSQQHTLETLLEEMKALRERVQAQEERITALENMLCELVDGTD", "length": 472 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q920M5-1", "protein_name": "Coronin-6", "gene_name": "Coro6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRRVVRQSKFRHVFGQAAKADQAYEDIRVSKVTWDSAFCAVNPKFLAIIVEAGGGGAFIVLPLAKTGRVDKNYPLVTGHTGPVLDIDWCPHNDNVIASASDDTTVMVWQIPDYTPVRNITEPVITLEGHSKRVGILSWHPTARNVLLSAGGDNVIIIWNVGTGEVLLSLDDIHPDVIHSVCWNSNGSLLATTCKDKTLRIIDPRKSQVVAERARPHEGARPLRAVFTADGKLLSTGFSRMSERQLALWDPNNFEEPVALQEMDTSNGVLLPFYDPDSSIVYLCGKGDSSIRYFEITEEPPFVHYLNTFSSKEPQRGMGFMPKRGLDVSKCEIARFYKLHERKCEPIIMTVPRKSDLFQDDLYPDTPGPEPALEADEWLSGQDAEPVLISLKEGYVPPKHRELRVTKRNILDVRPPASPRRSQSASEAPLSQHTLETLLEEIKALRDRVQAQEERITALENMLCELVDGTD", "length": 471 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92828-1", "protein_name": "Coronin-2A", "gene_name": "CORO2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSWHPQYRSSKFRHVFGKPASKENCYDSVPITRSVHDNHFCAVNPHFIAVVTECAGGGAFLVIPLHQTGKLDPHYPKVCGHRGNVLDVKWNPFDDFEIASCSEDATIKIWSIPKQLLTRNLTAYRKELVGHARRVGLVEWHPTAANILFSAGYDYKVMIWNLDTKESVITSPMSTISCHQDVILSMSFNTNGSLLATTCKDRKIRVIDPRAGTVLQEASYKGHRASKVLFLGNLKKLMSTGTSRWNNRQVALWDQDNLSVPLMEEDLDGSSGVLFPFYDADTSMLYVVGKGDGNIRYYEVSADKPHLSYLTEYRSYNPQKGIGVMPKRGLDVSSCEIFRFYKLITTKSLIEPISMIVPRRSESYQEDIYPPTAGAQPSLTAQEWLSGMNRDPILVSLRPGSELLRPHPLPAERPIFNSMAPASPRLLNQTEKLAAEDGWRSSSLLEEKMPRWAAEHRLEEKKTWLTNGFDVFECPPPKTENELLQMFYRQQEEIRRLRELLTQREVQAKQLELEIKNLRMGSEQL", "length": 525 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9BR76-1", "protein_name": "Coronin-1B", "gene_name": "CORO1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFLVLPLSKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIIAWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITEEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEEWVSGRDADPILISLREAYVPSKQRDLKISRRNVLSDSRPAMAPGSSHLGAPASTTTAADATPSGSLARAGEAGKLEEVMQELRALRALVKEQGDRICRLEEQLGRMENGDA", "length": 489 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9ULV4-1", "protein_name": "Coronin-1C", "gene_name": "CORO1C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWNRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPTANKKCDLISIPKKTTDTASVQNEAKLDEILKEIKSIKDTICNQDERISKLEQQMAKIAA", "length": 474 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9UQ03-1", "protein_name": "Coronin-2B", "gene_name": "CORO2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVTKMSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNTRFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKMVFKAPIKEKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRIRQLQLELKNLRNSPKNC", "length": 480 }, "evidence": [ { "id": "MGI:2444283", "url": "https://alliancegenome.org/gene/MGI:2444283#orthology", "database": "AGR" }, { "id": "HGNC:2256", "url": "https://alliancegenome.org/gene/HGNC:2256#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071009-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071009-5#orthology", "database": "AGR" }, { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WUM3-1", "protein_name": "Coronin-1B", "gene_name": "Coro1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFRKVVRQSKFRHVFGQPVKNDQCYEDIRVSRVTWDSTFCAVNPKFLAVIVEASGGGAFMVLPLNKTGRIDKAYPTVCGHTGPVLDIDWCPHNDEVIASGSEDCTVMVWQIPENGLTSPLTEPVVVLEGHTKRVGIITWHPTARNVLLSAGCDNVVLIWNVGTAEELYRLDSLHPDLIYNVSWNHNGSLFCSACKDKSVRIIDPRRGTLVAEREKAHEGARPMRAIFLADGKVFTTGFSRMSERQLALWDPENLEEPMALQELDSSNGALLPFYDPDTSVVYVCGKGDSSIRYFEITDEPPYIHFLNTFTSKEPQRGMGSMPKRGLEVSKCEIARFYKLHERKCEPIVMTVPRKSDLFQDDLYPDTAGPEAALEAEDWVSGQDANPILISLREAYVPSKQRDLKVSRRNVLSDSRPASYSRSGASTATAVTDVPSGNLAGAGEAGKLEEVMQELRALRMLVKEQGERISRLEEQLGRMENGDT", "length": 484 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9WUM4-1", "protein_name": "Coronin-1C", "gene_name": "Coro1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTGRIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKRVGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKKVRVIDPRKQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEMDTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDVNKCEIARFFKLHERKCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISLKHGYIPGKNRDLKVVKKNILDSKPAANKKSELSCAPKKPTDTASVQNEAKLDEILKEIKSIKETICSQDERISKLEQQLAKMAA", "length": 474 }, "evidence": [ { "id": "SGD:S000004421", "url": "https://alliancegenome.org/gene/SGD:S000004421#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z546", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z546" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z546", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z546" }, { "id": "SM01166", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01166" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF1899", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 69, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 422, "end_pos": 424 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z554-1", "uniprot_ac": "A0A8M6Z554", "uniprot_id": "A0A8M6Z554_DANRE", "mass": { "chemical_mass": 171140.0, "monoisotopic_mass": 171140.0 }, "refseq": { "ac": "XP_068073604", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073604" }, "gene_names": [ { "name": "LOC103909828", "type": "recommended", "evidence": [ { "id": "A0A8M6Z554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z554" } ] }, { "name": "LOC103909828", "type": "synonym", "evidence": [ { "id": "XP_068073604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073604" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z554/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_068073604", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073604" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068073604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073604" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z554" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC103909828", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z554", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z554", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z554", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01644", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01644", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103909828", "url": "https://www.ncbi.nlm.nih.gov/gene/103909828", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:103909828", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103909828", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z554", "url": "https://www.orthodb.org/?gene=A0A8M6Z554", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47331:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47331:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03564", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03564", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_068073604", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073604", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z554", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z554-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z554-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IXU5", "url": "https://www.uniprot.org/uniprotkb/A0AC58IXU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IXU5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IXU5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMTDHGSNLCTPAKVNEQIDNVQNKEVDEEIEVQSEELDTNVRRSTRERTQTDRMLAYQREESHKAERKLMHAYEKWKAEARKARSQLKLDISESELATLIDSLEREKDSVMNAYIKVRSNVTPPTDMRRKIDACDAVTKDIVKIAYERISGVDGGFDNETVKGHLRELLERDYARSVYGSTVSRISSKSSTPISQPSLNSILMAKRIEAAAELAAKEAEYATVIEEREQREKLRLLEEKQRKELEAQKGEFERLQVMKEVRAARARLEVYDKEETVDTVNQDEGLQQPVSPPMHKPVYLSSVNPTPNISSQSPNADVSQLAQAVQDSITLNRLPMPEPTVFSGDPIHFIEWKASFQSLIDKRHISSGDKLYYLKKYVTGPALKVLDGIFYRNDEEAYKDAWKRLLDRYGQPFIIQRAFREKLAYWPKIQSKDSVGLRNFSDFLNSCKDAMPHVKGLEILNDCEENRKLVSKLPDWAAARWNRQTTQTLSETQDFPTFQEFAHFMSVEAEVACNPVTSFHALHVSEPNKEKIYFKVSKPKANVFHTKTVTQHDNSKPTGKVNKPCLFCQNGEHQIHECSKFSARSLEERRQFVKDTRLCYGCLRLGHSAKDCRSRHCCNTCKGRHPTCLHDDSFSRKVRSSSAQSPENVHEGVATMSLSVESGCTPVNTSMIVPVWLSTHKDPVSEKLVYALLDTQSDSVFIECAVCKSLKVDSCPVTLKLTTLVGKDSLMSSERISGLRVRGFNSSLIIDLPPAYTKECIPVDHAHIPTMETASHWKHLATLADKIPPLQNCEVGLLIGYNCSRALAPREVILGTENEPYAVRTDLGWSIIGPSLTHFETQSSAAMCHRVSIKEIPAVTPTDVIKVLESDFKDTEGHTKVTSQEDIMFLRKLEENIRLNKDSHLEMPLPFRKRPYLPDNKPLAVIRLQHLKRRLMRDQEYREHYVTFMEEVIEKGNAEQVFEEGREGERWYIPHHGVYHSKKPGKLRIVFDCSARYKGTSLNDHLLTGPDLMNSLTGILLRFRQYPVALMCDVEKMFHQFHVDHADRDYLRFLWWRNGDFNSQPQTFRMTVHLFGASSSPGCANYGLKHLAREGERLYPLGSQFIMQDFYMDDGVSSIENTEKAIKLAEEARQLCALGSLRLHKFVSNDKEVLKTIPPSECAVDVTAVDLALTDQPLERALGIYWSLEQDNFKFRITVKDQPATRRGILSIVASLFDPLGFLAPFVLKGKTILQEMCRSGMGWDDNLPADLQSAWEHWKSELVNLEKIEVPRCIVPSGFGRIIRREIHHFSDASMSGYGQCSYLRLENEQGDISCSLLMAKSRVAPLKITTIPRLELAAAVVSVAVNDMLKEEMNLADAETFFWTDSQVVLGYINNEARRFHTFVANRVQRIHRTTTPQQWRYICSDENPADYASRGLSVNNLVTSNWFRGPKVLWERQIPPPMEISKQLPIGDPEVKKVQSLNTQTVQYSCLSDRLTKLSSWSKAIQAVARLIRRVRKD", 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"length": 1501, "header": "tr|A0A8M6Z554-1|A0A8M6Z554_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC103909828 PE=4 SV=1 CANONICAL=A0A8M6Z554-1" }, "locus": {} }, { "isoform_ac": "A0AC58IXU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z554/entry#A0AC58IXU5-1", "sequence": { "sequence": "MHIWVCFLFCSSSLFEHLVGRENKLLRCCTVFKDGYHNNKGTKEDSATSVHEFIPFISPTGLLQNDEEAYKDAWKRLLDRYGQPFIIQRAFREKLAYWPKIQSKDSVGLRNFSDFLNSCKDAMPHVKGLEILNDCEENRKLVSKLPDWAAARWNRQTTQTLSETQDFPTFQEFAHFMSVEAEVACNPVTSFHALHVSEPNKEKIYFKVSKPKANVFHTKTVTQHDNSKPTGKVNKPCLFCQNGEHQIHECSKFSARSLEERRQFVKDTRLCYGCLRLGHSAKDCRSRHCCNTCKGRHPTCLHDDSFSRKVRSSSAQSPENVHEGVATMSLSVESGCTPVNTSMIVPVWLSTHKDPVSEKLVYALLDTQSDSVFIECAVCKSLKVDSCPVTLKLTTLVGKDSLMSSERISGLRVRGFNSSLIIDLPPAYTKECIPVDHAHIPTMETASHWKHLATLADKIPPLQNCEVGLLIGYNCSRALAPREVILGTENEPYAVRTDLGWSIIGPSLTHFETQSSAAMCHRVSIKEIPAVTPTDVIKVLESDFKDTEGHTKVTSQEDIMFLRKLEENIRLNKDSHLEMPLPFRKRPYLPDNKPLAVIRLQHLKRRLMRDQEYREHYVTFMEEVIEKGNAEQVFEEGREGERWYIPHHGVYHSKKPGKLRIVFDCSARYKGTSLNDHLLTGPDLMNSLTGILLRFRQYPVALMCDVEKMFHQFHVDHADRDYLRFLWWRNGDFNSQPQTFRMTVHLFGASSSPGCANYGLKHLAREGERLYPLGSQFIMQDFYMDDGVSSIENTEKAIKLAEEARQLCALGSLRLHKFVSNDKEVLKTIPPSECAVDVTAVDLALTDQPLERALGIYWSLEQDNFKFRITVKDQPATRRGILSIVASLFDPLGFLAPFVLKGKTILQEMCRSGMGWDDNLPADLQSAWEHWKSELVNLEKIEVPRCIVPSGFGRIIRREIHHFSDASMSGYGQCSYLRLENEQGDISCSLLMAKSRVAPLKITTIPRLELAAAVVSVAVNDMLKEEMNLADAETFFWTDSQVVLGYINNEARRFHTFVANRVQRIHRTTTPQQWRYICSDENPADYASRGLSVNNLVTSNWFRGPKVLWERQIPPPMEISKQLPIGDPEVKKVQSLNTQTVQYSCLSDRLTKLSSWSKAIQAVARLIRRVRKD", "length": 1173, "header": "tr|A0AC58IXU5-1|A0AC58IXU5_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC103909828 PE=4 SV=1 CANONICAL=A0A8M6Z554-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 123, "start_aa": "Thr", "end_pos": 123, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr123", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 860, "start_aa": "Thr", "end_pos": 860, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr860", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:103909828", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103909828", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z554" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z554", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z554" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 745, "end_pos": 747, "annotation": "n_glycosylation_sequon" }, { "start_pos": 802, "end_pos": 804, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z554", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z554" }, { "id": "PS50158", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC-type", "eco_id": "ECO_0000259", "start_pos": 599, "end_pos": 614, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 123, 860 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 668, "end_pos": 670 }, { "start_pos": 745, "end_pos": 747 }, { "start_pos": 802, "end_pos": 804 } ] }, "class_list": [], "section_stats": [ { "table_id": 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This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017210371.2. 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"MERDKHRLTCSQCGKSLASKKSLNEHMMIHTGEKPFTCTQCGKSFRHSSSLYKHLKIHTGKKNHRCDQCSKTFLRASGLKLHLRTHTKEKPHSCSECGKSFTEKSYLRLHQKIHTGAKEYMCFECGKTFITAEHLKQHQRIHTKEKPYKCSHCDKRFSQLAYLKSHERIHTEEKPFTCTQCGKSFRHSSSLKEHMRIHTGEKPYKCSYCDERFSQLACLKSHKRIHTGEKPFTCTQCGKSYRLSTSLRKHMMIHTAGKPFTCTQCGTSFRLSSHLNKHMRIHTGEKPSTCTQCGTSFRLSDSLKEHMLIHTGEKTHRCDQCGKAFLRASALKLHLRTHSKEKPYSCFECGKSFTQPASLRSHQKIHTGVKEYVCFECEKTFITARRLKEHQRIHTGEKPYTCTQCGKSFRLSSCLNEHRRIHTGEKPYTCTHCGTSFRHSSSLYKHMKIHTGEKQHT", "length": 457, "header": "tr|A0AC58J035-1|A0AC58J035_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC100537032 PE=3 SV=1 CANONICAL=A0A8M6Z578-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100537032", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100537032", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z578", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z578" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z578", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z578" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z578", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z578" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": 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"domain_list": [ { "evidence": [ { "id": "A0A8M6Z578", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z578" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 82, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z5G4-1", "uniprot_ac": "A0A8M6Z5G4", "uniprot_id": "A0A8M6Z5G4_DANRE", "mass": { "chemical_mass": 41726.0, "monoisotopic_mass": 41726.0 }, "refseq": { "ac": "XP_017209950", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209950" }, "gene_names": [ { "name": "LOC108182329", "type": "recommended", "evidence": [ { "id": "A0A8M6Z5G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5G4" } ] }, { "name": "LOC108182329", "type": "synonym", "evidence": [ { "id": "XP_017209950", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209950" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M6Z5G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5G4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017209950", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209950" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017209950", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209950" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5G4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5G4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108182329", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5G4", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z5G4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z5G4", "database": "AlphaFoldDB", "categories": [] }, { "id": "108182329", "url": "https://www.ncbi.nlm.nih.gov/gene/108182329", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108182329", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108182329", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z5G4", "url": "https://www.orthodb.org/?gene=A0A8M6Z5G4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14196:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14196:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017209950", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017209950", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z5G4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z5G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5G4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEETRRHKKITENTHSLKRKGKKCVTCTQCGISLVNNWSLRNHMMIHTGEKPFKCSLCGKSFRHSSNFGRHMLTHTGEKTHKCDQCSKTFLRTSELKRHLRVHTEGKPYSCSVCGKSFRHQDGLRDHQKFHTDVREHMCFECEKTFITAVKLKIHERIHTGEKPYKCSHCDKRFCTLGSLKIHKRTHTGEKPYKCSLCNKTFSVLENLQRHARTHTGEKPYTCSHCDKRFSTLGNLKTHERIHTGEKPYMCSHCDKRFCQLESLKSHERTHTGEKPYTCSHCDKRLCSLGSLKTHERIHTGEKPYKCSHCDKRFSTSGSLKSHERTHTGEKPYKCSHCDKRFSDSRNMKKHERIHAT", "length": 357, "header": "tr|A0A8M6Z5G4-1|A0A8M6Z5G4_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC108182329 PE=3 SV=1 CANONICAL=A0A8M6Z5G4-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z5G4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5G4/entry#A0A8M6Z5G4-1", "sequence": { "sequence": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z5G5-1", "uniprot_ac": "A0A8M6Z5G5", "uniprot_id": "A0A8M6Z5G5_DANRE", "mass": { "chemical_mass": 93115.0, "monoisotopic_mass": 93115.0 }, "refseq": { "ac": "XP_017210661", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210661" }, "gene_names": [ { "name": "LOC108183315", "type": "recommended", "evidence": [ { "id": "A0A8M6Z5G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5G5" } ] }, { "name": "LOC108183315", "type": "synonym", "evidence": [ { "id": "XP_017210661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210661" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M6Z5G5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5G5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017210661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210661" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational 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This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017210661.1. 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[ "Protein" ] } ], "sequence": { "sequence": "MMDGLVRRYQESGVDPPAVLYVDCGCCTDVGETKLKARFRGWPELTVKLDIWHFMRRIAVGCTTDAHQLYPIFMSRISACIFEWDAADVSLLRQAKRALLMSQGWPALTDADVNKHLTREELALHCRRRTRGEETTILLLEQLLTELMSNKGNDSLGVPLLDKERMGHIWSVQKKHIKCIQDPPGVVLYTETGSITKGGVLLRTYRCARGSTSLESFHLHLNRFIPGYSENSLNFQIYLLEGLNRWNQDREAASLASEPSALRSYTGELVHCVNCNFKKLFGRKVVPNFCPPARYTGELIGVQYLFQQTGQALQNMNPECEQTAELIEDLNVDEREEDDGFCDISEDHTIVDPEAALSPSSSTLRSGSSTAVTSSVASLPVSTCPALVPDPPAQPEEPISPVPLEPEEATEDDDEDNDDDDDDDGDEETAVDYQNIPGFQHVDRLAEYLVELRTHKSLSLTNQEANEIIGLWQSLHDQDKKRVVYAARHQKRLLSGRFKTPKKPTHTPGVESTTRCVLGASSAPAQWPDCCRLVETIFIRLCTIHPSPKRKGKGTLSRWSLILQDYRRIRQLVLGNSLVMGGTSMQLVEVNQNTLIQWFNNRQKKQELSVLLQGIQLPQHLPEAQEPLPVAKSLRTEPDQPGEQHQYVLPESTAGQARQRQTSVGRPPLRPKAPVQTQVIFTPPAPGASLQMVPNIYIPATPGYQGMPMFQGVPMFQAVPMVQGIPMAQGIPMMQGVQMAQGIPMVQGMPLRQPPLQPTMSSTSSQPAASPSTSGAIPKRPYRRTVQANTCKKCGQFKTNSTGHSQLRGRVYCPQTETLTKEEWLEEMKRTNPK", "length": 834, "header": "tr|A0A8M6Z5G5-1|A0A8M6Z5G5_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio 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CANONICAL=A0A8M6Z5G5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 701, "start_aa": "Thr", "end_pos": 701, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr701", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:108183315", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108183315", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 800, "end_pos": 802, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 701 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 800, "end_pos": 802 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z5K5-1", "uniprot_ac": "A0A8M6Z5K5", "uniprot_id": "A0A8M6Z5K5_DANRE", "mass": { "chemical_mass": 53566.0, "monoisotopic_mass": 53566.0 }, "refseq": { "ac": "XP_017210065", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210065" }, "gene_names": [ { "name": "LOC103910027", "type": "recommended", "evidence": [ { "id": "A0A8M6Z5K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K5" } ] }, { "name": "LOC103910027", "type": "synonym", "evidence": [ { "id": "XP_017210065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210065" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z5K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017210065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210065" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017210065.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017210065", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210065" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5K5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC103910027", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K5", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z5K5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z5K5", "database": "AlphaFoldDB", "categories": [] }, { "id": "103910027", "url": "https://www.ncbi.nlm.nih.gov/gene/103910027", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003886", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003886", 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] } ], "sequence": { "sequence": "MGFYPTNTDLTLCKKMDEDCSLITDKGLVHSVVISDIIMRLSLLLAHLLVLFSVLALVRTQTTAKLLADPSYDPCNNYTVLNDSWRSTKNTYNSSLLYCDQYVNWFGWYRLFINGQSAQMPDTCVAMYSCGAQGPLWLSGGHPTVQDGVVTRDVCARDTSCCNVKARPIRVKACPGGYYVYELVNPSIGCYNAYCADVANNTATPVTTLAAPGIFYTFGSSAGDAINPADDDGGSSAITLLSPFQFFGRTYQQIYVNNNGHLTFSQASSEFVPYSFPAFGSQDIIAGLWTDLDNRVRGVISYHQYTNGSVLTRATQDINSYFPNLTFTASWVFVATWDKVAYFSLTNTETSFQVVLISGGNYSFILMNYGDIAVTRHQVEAGYDTVTSTNYFVIPGSINGSSILNLNTSSNVGVQGRWAFRVDSGPRSNIFKRVVGLQVRFSSFVDLTQNGNTDIVLQQVKQELVRYGLPNNIMIKVRKVQKINL", "length": 485, "header": "tr|A0A8M6Z5K5-1|A0A8M6Z5K5_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC103910027 PE=4 SV=1 CANONICAL=A0A8M6Z5K5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z5K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K5/entry#A0A8M6Z5K5-1", "sequence": { "sequence": 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"MRLSLLLAHLLVLFSVLALVRTQTTAKLLADPSYDPCNNYTVLNDSWRSTKNTYNSSLLYCDQYVNWFGWYRLFINGQSAQMPDTCVAMYSCGAQGPLWLSGGHPTVQDGVVTRDVCARDTSCCNVKARPIRVKACPGGYYVYELVNPSIGCYNAYCADVANNTATPVTTLAAPGIFYTFGSSAGDAINPADDDGGSSAITLLSPFQFFGRTYQQIYVNNNGHLTFSQASSEFVPYSFPAFGSQDIIAGLWTDLDNRVRGVISYHQYTNGSVLTRATQDINSYFPNLTFTASWVFVATWDKVAYFSLTNTETSFQVVLISGGNYSFILMNYGDIAVTRHQVEAGYDTVTSTNYFVIPGSINGSSILNLNTSSNVGVQGRWAFRVDSGPRSNIFKRVVGLQVRFSSFVDLTQNGNTDIVLQQVKQELVRYGLPNNIMIKVRKVQKINL", "length": 447, "header": "tr|A0AC58GZ47-1|A0AC58GZ47_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC103910027 PE=4 SV=1 CANONICAL=A0A8M6Z5K5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103910027", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910027", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", 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"end_pos": 309 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 399, "end_pos": 401 }, { "start_pos": 407, "end_pos": 409 }, { "start_pos": 77, "end_pos": 79 }, { "start_pos": 82, "end_pos": 84 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z5K8-1", "uniprot_ac": "A0A8M6Z5K8", "uniprot_id": "A0A8M6Z5K8_DANRE", "mass": { "chemical_mass": 45316.0, "monoisotopic_mass": 45316.0 }, "refseq": { "ac": "XP_017210822", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210822" }, "gene_names": [ { "name": "LOC108183429", "type": "recommended", "evidence": [ { "id": "A0A8M6Z5K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K8" } ] }, { "name": "LOC108183429", "type": "synonym", "evidence": [ { "id": "XP_017210822", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210822" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M6Z5K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017210822", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210822" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017210822", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210822" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5K8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K8#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5K8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108183429", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K8", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z5K8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z5K8", "database": "AlphaFoldDB", "categories": [] }, { "id": "108183429", "url": "https://www.ncbi.nlm.nih.gov/gene/108183429", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108183429", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108183429", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z5K8", "url": "https://www.orthodb.org/?gene=A0A8M6Z5K8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017210822", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210822", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z5K8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z5K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDPQEKTDLMVLKEETHGQNEIDEKQQFMKPQEITTDEKPTLTKKTSSHGRPRESKSGCNFSCKQCRKSFSQKSNLDVHMRVHTREQPYTCEQCGKSFGQIQSFKAHMRIHTGEGKFTCQECGKSFYQAGNFAAHMRIHTGEKPFSCKQCGKSFSQKSNLDVHMRVHTREQPYTCEQCGKSFSQKQSFKTHMRIHTGEKPFSCKQCGKSFCQKPNLDVHMRVHTREKPYTCEQCGKSFGHKQDLDIHMRIHTGEKPYTCTECGKSFPHISSLKHHMISHTRERPFTCAQCGKSFTTKTSLKNHMNGHTGTIVFTCDQCGKSLKRKDTIKKHMKIHSREDRFRCSECGKGFKSKRSLNTHMKLHNAEQSPQH", "length": 392, "header": "tr|A0A8M6Z5K8-1|A0A8M6Z5K8_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC108183429 PE=3 SV=1 CANONICAL=A0A8M6Z5K8-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z5K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5K8/entry#A0A8M6Z5K8-1", "sequence": { "sequence": 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CARD domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210847" }, "gene_names": [ { "name": "si:ch211-207e19.2", "type": "recommended", "evidence": [ { "id": "A0A8M6Z5L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5L8" } ] }, { "name": "si:ch211-207e19.2", "type": "synonym", "evidence": [ { "id": "XP_017210847", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210847" } ] } ], "protein_names": [ { "name": "NLR family CARD domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "XP_017210847", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210847" }, { "id": "A0A8M6Z5L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5L8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017210847.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017210847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210847" } ] } ], "disease": [ { "disease_id": "DOID:0050854", "recommended_name": { "id": "DOID:0050854", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "Muckle-Wells syndrome", "description": "A syndrome characterized by episodic skin rash, arthralgias, and fever associated with late-onset sensorineural deafness and renal amyloidosis that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q44." }, "synonyms": [ { "id": "DOID:0050854", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "MWS", "description": "" }, { "id": "DOID:0050854", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "neutrophilic urticaria", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle-Wells syndrome", "description": "An intermediate form of cryopyrin-associated periodic syndrome (CAPS) and is characterized by recurrent fever (with malaise and chills), recurrent urticaria-like skin rash, sensorineural deafness, general signs of inflammation (eye redness, headaches, arthralgia/myalgia) and potentially life-threatening secondary amyloidosis (AA type)." }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle-Wells syndrome", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "neutrophilic urticaria", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "MWS", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle Wells syndrome", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "urticaria, deafness and amyloidosis", "description": "" }, { "id": "MIM:191900", "resource": "MIM", "url": "https://www.omim.org/entry/191900", "name": "Muckle-Wells syndrome", "description": "Muckle-Wells syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050854", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050854" } ] }, { "disease_id": "DOID:0080208", "recommended_name": { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol." }, "synonyms": [ { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "nonalcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "non-alcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "NAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-related steatotic liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MASLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic-associated fatty liver disease", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "NAFLD2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "fatty liver disease, nonalcoholic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "liver disease, alcoholic, susceptibility to, 1", "description": "" }, { "id": "MIM:613282", "resource": "MIM", "url": "https://www.omim.org/entry/613282", "name": "Non-alcoholic fatty liver disease 1", "description": "Non-alcoholic fatty liver disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ] }, { "disease_id": "DOID:0080270", "recommended_name": { "id": "DOID:0080270", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080270", "name": "autosomal dominant nonsyndromic deafness 34", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q44." }, "synonyms": [ { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "hearing loss, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "DFNA34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "autosomal dominant nonsyndromic deafness 34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "deafness, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MIM:617772", "resource": "MIM", "url": "https://www.omim.org/entry/617772", "name": "Deafness, autosomal dominant, 34, with or without inflammation", "description": "Deafness, autosomal dominant, 34, with or without inflammation" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080270" } ] }, { "disease_id": "DOID:0090029", "recommended_name": { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "CINCA Syndrome", "description": "An autoimmune disease characterized by neonatal onset of cutaneous symptoms, chronic meningitis, and joint manifestations with recurrent fever and inflammation that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q." }, "synonyms": [ { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "IOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "NOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic infantile neurological cutaneous articular syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "Chronic Infantile Neurological, Cutaneous, and Articular (CINCA) syndrome is characterized by skin rash, joint involvement, chronic meningitis with granulocytes and, in some cases, sensorineural hearing loss and ocular signs." }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA/NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Neonatal-Onset Multisystem Inflammatory Disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic infantile neurological cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal onset multisystem inflammatory disease", "description": "" }, { "id": "MIM:607115", "resource": "MIM", "url": "https://www.omim.org/entry/607115", "name": "Chronic infantile neurologic cutaneous and articular syndrome", "description": "Chronic infantile neurologic cutaneous and articular syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090029", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090029" } ] }, { "disease_id": "DOID:0090062", "recommended_name": { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "familial cold autoinflammatory syndrome 1", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP gene on chromosome 1q44." }, "synonyms": [ { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "FCAS1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "Any familial cold autoinflammatory syndrome in which the cause of the disease is a mutation in the NLRP3 gene." }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "NLRP3 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP3", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome type 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold inflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "FCAS1", "description": "" }, { "id": "MIM:120100", "resource": "MIM", "url": "https://www.omim.org/entry/120100", "name": "Familial cold autoinflammatory syndrome 1", "description": "Familial cold autoinflammatory syndrome 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090062", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090062" } ] }, { "disease_id": "DOID:0090063", "recommended_name": { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "familial cold autoinflammatory syndrome 2", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP12 gene on chromosome 19q13." }, "synonyms": [ { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "An autoinflammatory disease caused by mutations in the NLRP12 gene. It is characterized by periodic fevers beginning in the first year of life that are triggered by cold exposure. Episodes occur more than once per month." }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NALP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NAPS12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome type 2", "description": "" }, { "id": "MIM:611762", "resource": "MIM", "url": "https://www.omim.org/entry/611762", "name": "Familial cold autoinflammatory syndrome 2", "description": "Familial cold autoinflammatory syndrome 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090063" } ] }, { "disease_id": "DOID:12351", "recommended_name": { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "alcoholic hepatitis", "description": "" }, "synonyms": [ { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic hepatitis", "description": "" }, { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic liver disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12351" } ] }, { "disease_id": "DOID:1555", "recommended_name": { "id": "DOID:1555", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1555", "name": "urticaria", "description": "A skin disease characterized by skin rash notable for pale red, raised and itchy bumps, located_in the upper dermis." }, "synonyms": [], "unlinked_id_list": [ "DOID:0060220" ], "evidence": [ { "id": "1555", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1555" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:9452", "recommended_name": { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes." }, "synonyms": [ { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Fatty change of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Steatosis of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "alcoholic fatty liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic lipidosis", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "SLD", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "fatty liver disease", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "fatal neonatal hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5L8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5L8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-207e19.2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5L8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z5L8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z5L8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "565475", "url": "https://www.ncbi.nlm.nih.gov/gene/565475", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565475", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565475", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z5L8", "url": "https://www.orthodb.org/?gene=A0A8M6Z5L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017210847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210847", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z5L8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z5L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041210-227", "url": "https://zfin.org/ZDB-GENE-041210-227", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKDFNENRSRITDAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTDHEIRQIEAASRRHQSLEIQVECKHLFEAAEQHEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETEGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVDKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKKQGWFFIQISKNKGMIDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKGEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSADLSPAQWSALVFVLLTSEEELEVFELQKFQRSDECLIRLSAVIKTSKRALLQGCYLTVRSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLQFCNLTVQCCESLSSALQSSNCVLRELDLSINDLQDSGVKKLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKYVCFLTLDPNTAHTELILSEENREVKSVRENQPYPDHPDRFDYYHQVLCRESVCGRCYWEIDWSGDGVVCISVSYKSIRRKGGGDECVFGYNAQSWSLRCDSSRFKFWHNNTHTDLPVEALSSRIGVFVDHSAGILIFYNIYRDTMSLIHSVQTTFTEPLCAGFRVYYPGSSVKLS", "length": 995, "header": "tr|A0A8M6Z5L8-1|A0A8M6Z5L8_DANRE Isoform 1 of NLR family CARD domain-containing protein 3 OS=Danio rerio OX=7955 GN=si:ch211-207e19.2 PE=4 SV=2 CANONICAL=A0A8M6Z5L8-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z5L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5L8/entry#A0A8M6Z5L8-1", "sequence": { "sequence": "MKDFNENRSRITDAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTDHEIRQIEAASRRHQSLEIQVECKHLFEAAEQHEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETEGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVDKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKKQGWFFIQISKNKGMIDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKGEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSADLSPAQWSALVFVLLTSEEELEVFELQKFQRSDECLIRLSAVIKTSKRALLQGCYLTVRSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLQFCNLTVQCCESLSSALQSSNCVLRELDLSINDLQDSGVKKLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKYVCFLTLDPNTAHTELILSEENREVKSVRENQPYPDHPDRFDYYHQVLCRESVCGRCYWEIDWSGDGVVCISVSYKSIRRKGGGDECVFGYNAQSWSLRCDSSRFKFWHNNTHTDLPVEALSSRIGVFVDHSAGILIFYNIYRDTMSLIHSVQTTFTEPLCAGFRVYYPGSSVKLS", "length": 995, "header": "tr|A0A8M6Z5L8-1|A0A8M6Z5L8_DANRE Isoform 1 of NLR family CARD domain-containing protein 3 OS=Danio rerio OX=7955 GN=si:ch211-207e19.2 PE=4 SV=2 CANONICAL=A0A8M6Z5L8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "A0A8M6Z5L8", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M6Z5L8" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0A8M6Z5L8", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M6Z5L8" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:565475", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565475", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JW23-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPATAKDALHRLSTYLEELEAGELKKFKLYLGIAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGEDLVRVTPSNGLCSLESQSTCLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGPWCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTSRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFTAMYCALHGREAVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAEDGPPEPPGAQTQSTHSQERNILPDIYSAYLSATICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIANRNLIRLDLSGNSIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSNNSHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVNTCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGISQTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFGMDLNKVTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1PS14-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:dkey-222h21.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNMLQRIKNQHKTSLKNKYERLFEGIEVKETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPENLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGIDVSDASVYSGICTEILKEESVIQQRKVYSFIHLSFQEFLAAFHVFYHHITCSTEASLDSLHDLQKRIINKSTESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKRSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELKLQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITPGLRKYACVLTLDPNTAHTHLVLSEKNRQARNVTDPQPYPDHPDRFKNNEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYSCDTIYTVWHNNKSADIIAPSACTNRVGVYVDVPSGSLSFYSVTDTHTLTLIHTFNTTFTEELYTGFGIYPEASVSLCQI", "length": 892 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3ANC0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch73-168d20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSRKRRSSSPESSCVSIKSDASMDNPPTLRLGESPAKHRRSSSLGSSCVSMKSDASMDNPPTLRLGESPAKHRRSSSPESSCVSMKSDASMDNPPTLRLGESPAKHSDNQKRSQSNKGQKQLDAIFKDLEETNIDEMRKVLRRFKMLLSPDYSVRDEEEEEGQRQINEAFLKITLHALQKMNQTDLASKLQTKLISVSQQQLKSRLKQRFERFTEGVSNRGNTKLLNDIYTEVYITEGGAGNIDDEHEVRQIETSSSRFPEIPIRCCDIFKSLLGQDKAIRTVLTKGVAGIGKTASVQKFILDWAEGKANQDVHFIFPLPFRDLNLIKEKRMSLMELLCCFCPELKPIDYNNFKTVFIYDGLDEWRLPLDFRNNEILWDMNKVASVDALLTNLLQGNLLPSAVHWITTRPAAACQIPAEFIDRVTEVRGFKDLQRAEYFWKRIKDQNLANKIITHIQSSRSLHIMCRIPVFCWISATVLEKIFGEANSADIPKTLTQMFIHLLIVQTNLKTQKYDRECDVNLEKARKSILSLAKLAFEQLEKGNLIFYEEDLKQCGIDVREASVCSGVCTQIFREEFGLQLQKVFSFVHLSVQEFLAALFKFLSFAEENNKSSMTQFMKNEVDRALQSPNGHLDLFLRFLLGLSLDSNQTLLQGLFTPLDTSHSRDETIEYIKSKIRENPSPERSINLFYCLNELNDHSLVQEVQTYLTSTRSHRLSGVKLSPALWSALVFVLLNSTKDLDEFELRQYDFTEECLLRLLPVVKASRKADLKGGNLTDQICSALASALSSSSCCLRELDLSENRLQLSGIRLFSAGLKSPNCKLEILKLSNCSIREEGCASLVSALLSNPSHLRELNLNSNQPGYSTVKLLSDLLENPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLNGSNIREKDCAAFISSLLSNPFHLRELSLSWNKPGDSGVKLLSDLLKDSRCKLEKLELECCSIIEEGCAALALALVSNPSHLRELNLNNNEPGDLGVNLLSFLLKNPQCKLEKLELEYCCIGAKSCASLASAFVSNPSHLRELNLNWNTPEYPAVKLLSDYLKDPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLEYCCIGEEGCAALVSGLKSNPSHLRELNLNRNEPGNLGAKMLSDLLKDPLFELEKLELDDCSIENNGFADLVSGLKSNPSNIRELNLNSNKFIFSGLNLLCDLLRDQQCKLRKLQLECCNIDEEGCAALALALISNPSHLRELNLNYNNPGGLGVKLLSVLLKNPHCKLEKLELSHCSISENYLAALNSALSSNPAHLRELNLNYNENTRQ", "length": 1388 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQ59-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKIFQNLTAESGKGIRDYVVQIRFCFIMDDTQISRDENVSPGCSSVHQKRSDPEPSCVSMRSDWSMDPPISFKSKDTPPDFSSVHQKSTESEPSCVSMRSDDESVDQPLHVRSGDTETDLSHEALNTFRSDLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIIPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLMNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHLLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDGFEEIKKPSLWSKVKDLLYLNSSQLVSLSELHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQIILQRLMILKSRSIQINKTVEYIKMKIRTIDSPEKFINLFHCLNELGDHSLVEEIQQYLKSGRINRAKLSESQWSAVAFVLLTSEKKLEEFHINEFVGETEKIFIFMKLLPVIRECRSVQLNNCGLTDEGCAALASALRSNPEHLRELNLSGNRLGDSVTLLSALLEDPRCNLEILWLSYCGLTDEGCAALASALRLNPEHLRELNLSHNNISKSTVKLLSDLKHNPHNKLETLYI", "length": 837 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B0M3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "si:dkey-7i4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESDEQHNDTLVQMGSSGNSGINADLRAEKEATVIAPLLNGNNITGPVTFNYCSNSAENEPQKYPKTADKHTEKQDDLKLQKILETHRTYMKKKVDCILDCTKENAEHFKAFYTELFIAEGDMQDVNQEHEILKIDDAFKKKKASLRSIRCKDIFAELKAKSEKNTVLTKGIAGIGKTVSVRKFILDWAEGQTNHDIHCVFLLPFREINLMTNEDFNLHEFLLKFYPELKELETSVLFQQCNLAFIFDGLDESRLPLNFKSRTLNNVEERSSVDMLFTSLVKGNLLPSALVWVTSRPAAANQIPPRYVGLFTEVQGFTDQQKEKYFRNRIADETQASKIISHIKTSRSLYIMCHIPVFCWITATVLQDILQRNIESIGTTLTEMYIHFLLIQMNMKSQKYDPEEEREYAKLLEANREVILKLAKLAFEQLKKENVVFYEQDLKDCGIDVNVEFTGMIAEIFKVEHGLHEAKVFYFVHLSVQEFLAAVYVFFCFLNRNTHELTFFFESSQNTPRELQFLFKKTFRKVKFHDLIKRATDKAMRSKRGHLDLFLRFLLGISLESSQNLLKGLFSHVIDTTRSIKKISPHFKHLQNKNISCDCSVNLFFCLLELKDHSLYEEIQRSLNSDRRPSKELSSSMCTVLTYIVLMSEKELDELNPKRFTSSQENYRKLVPAVRCCRKALFNGCGLDEMSFQTISSALQSSDSYLTELELSNNHLQDSGVKLLSDGLKSSHCQLNILRLCGCGLTDQSCESLSSALQSSNSVLRELDMSNNMLKDSGVKLLAVALKSLNCKLERLRFSMCNLTAESCESLSSVVELSNSVLRELDLSNNDLQDSGVKLLSDGLKRNCRLEILRLSGCMVTEVGCGFLSSALSSTTSTLRELDLSYNHPGDSGEKLLSDAHNQPNCRLCVDHGGEFRLTTGLHKYARFFTLDPNTANARLILSEENRKVTCVRKKQPYPDHPDRFEGYLQVLCRESVCGRSYWEIEWTGVVFISVSYSSIGRMGSDKECWFGFSNQSWSLFCSSDRCSFTHSSTEIDLPVKHTSSRIGVYVDHSAGTLSFYSVSDTVSLIHSVQTTFTQPLHPGFYISLGSSVKLC", "length": 1096 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YSM0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch211-181d7.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSHKQTLKYFSPVCSSVQQERSDSAEPSSVSVKSHWSIDPPPQMTERRDSLSLALQERSDSPEPSHVSMKSDWSIDPPPQMKEENRSLVQQERSPKSSCVSMKRDWSIDPPPQMNDEDGQKRLSLVQQERSDSAEPSLVSMKSDWSIDPPPQMKDGDRQKSLSLVQQERSDSPEPSHVTMKSNWSIDPPPQMTDRRDSLRQIPRPRPGAEEPISKKMKYDESVIKSQECMENPSLIFSHEVNTFRVNLLKKFQCLYEGMVTQDNPALLNEIYTELYITESESGEISNEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPETKEIDIFSDKYKILFIFDGLDECRLLLNFKSNEILQHVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLMAQINTKDMKYTGKKDKDMIFKLGKLAYEQLERGNVIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFIHLSVQEHLAALYVHLLFTNHNRNVFEQMTKKTSKTLDILDCFHSNSPENVLLSELHQKAVDEALQSKNGHLDLFLRFLLGLSLESNQILLQELMIKFRSSSDSSEKTVEYIKKRINNICLPEKSINLFYCLNELGDHSLVKEIQQYMDYGTLAETKISCGQWSALVFILLTVEQAMDVFELNKFIGLKKSSDEVLRKLLPVIKKSRSAIMDDCNITAEGCAYLASALGSNPSYLRELDLSANKLQDSGIKKLSKGLQDSHCKLEKLNLYHCGVTNEGCAALASALKSNPEHLRDLNLSENKIGNLGLTCLSEILKNSLCKLEILRLCQCGITDCTDLASALISNPEHLRELELSLNKIGDSGVTALCAAFEDPRFKLEKLGLSGCGLTDEGCAALTSALRSNHEHLRDLDLSGNKVDKEVKGSILQRILEKLNNIQILSV", "length": 1068 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YU37-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch73-24k9.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDNQTFSDAPVCSNESNPEFEPSCVSMKSDQSMDPPMKFKEGHTSADLSDRLNPPGSSCVSMKSDWSMDRPIQFKEEHSSADLSNKSNPGEPSCVSSKSDQSMGPPINVMEEHSAADLRLDPHLKQNGLRSNLLRKFQCLYEGTAMQGDPTLLNEIYTELYITESDSGEINNKHELRQIETRSRRSATEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEEKENQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEQFKVLFIFDGLDECRVSLDFKCDVKLHDVSESASVDVLLTNLIMGNLLPSALIWITSRPAAADLIPSEFVHRVTEIRGFNDPQKEEYFRKRIRDQFLADIIIINLKSSRSLHIMCHIPVFCWISATVLEKIFSQAQSGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEVRDEDMILKLGKLAFEQLVKGNLIFYEEDLRECGLDVTEASVYSGLCTQIFREEFGFYQGKVFCFVHLSIQEHLAALYAHHSLTNKNRNVFKQTKPSLLSKVLNQKKHDSLSVLHQRAVKEASQSKNGHLDLFLRFLLGLSLESSGTLLRELLTQTGSCSYNKEETVQYIKQKIRENRSPERSINLFHCLNELGEDSLMQEIQDYLSSGEIKETKLSSSQWSALVYVLLTSEKKMDFFDLSKFIGPQLRADVVLQKLLPVVKESRSVRLGDCKVTDKVCAALASALRLNSSHLTQLDLIGNKLGDSGVKLLSDGLKDPHCKLKNLMMRDCGVTDEGCAALASALRSNSTHLTELNLNENNLGDAGVKRLSDGLKGPHCKLEILRLWRCGVRDEGCAALASALSSNSTHLKELELSDNKLGDSGVKLLSDALKDPHCKLEKLRLNGCGVREQGCVSLALALRFNPSSHLTELDLTSNELGKSGVKLLSDLRDDPRYKLRHLACDMFGRIIVSSGGGRLDELLPTTSTET", "length": 978 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkey-165e24.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHRVRSGSCVSSSVSLKSDCSKEDPPKFSEKTPSSAQSVRSGLCVSSFVSLKSDCSKEDPPKFSEKTPSSAQSDEDELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNELEKFKQILQEENRQEFVKDYNENRSRITEAALDLTLFFLREMKQDHAADTLQDELLFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAVSRRHQSLETQVEFKHLFKAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQLFPETKGLNLTRSTQFKVLFILDGLDECRLPPNFAGNEMCCDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILNLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSQGKLAFQQLERNNVIFYESDLNDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEGIIAYIKQKLEGNLSPERSINLFYCLSELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELWKFQRSDECLIRLSAIIKNSKRALLQSCNLTVQSCKSLSSILQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLATCNLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSEHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDTLNLDHVGDMRITAGPRKYVCFLTLDPNTANTQLKLSKENRKVKHVREDLRIMRKDRRYPYHPDRFDPVFQVLCRESVCGRCYWEIDWSGDHGVFISVSYKSIRRKRGDACEFGCNAQSWSLLCLSSRFTFRHNNTHTHVPVKPLSRRIGVFVDHSAGTLIFYNIYKDTMSLIHSVQTTFTEPLCPGFGFYSGSSVKLS", "length": 1137 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1F5-1", "protein_name": "Protein NLRC3", "gene_name": "si:dkey-23k10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METEGPDSPEPSCVSLRSDHSKAHHVLFKDEDPFEYSSGQTGRSSPTPSHVSLASNMSINQPLEFKSCSNTLLLKEIQEAIQSVLRIRFQCLHEGLSKHSVLIPLNDIYTELYITEGEGGELNNEHEIRWIETACRRALTEDRPVNLNDIFKPLHGQDRPIRTVLTKGVAGIGKTVSVQKFIIDWAEGEANQDIWFIFPLPFRELNLLKDQSFSLKGLLQYFMNIELDISLHEGKIMFIFDGLDECRLPLDFHNNVKLCDVTESASVDVLLTNIIRGNLLPSSLIWITSRPAAADVVPSKCIHRVTEVRGFSDPQKEEYIRKKVSDQTLSDRIISHLKSSRSLYIMCHIPVFCWISATVLKKMLSEAESAEIPNTLTQMYTQFLMLQLRIKNEKAYDKKSSDIDIVLKLGELAFQQLEKLNLIFYKEDLREYGIDEQEASVYSGLFREESGMFQGKVYSFVHLSVQEHLAALYVYLYFVNENINKLNQPNFLTSILKCVPTVFDVYQTAVKKALQSTSGHLDLFLRFLLGFSLESNQNLLGDLQVQTESSSDSREQIVGFIKEKIKESPPPEKMINLFHCLNELNDHSLVEEIQDFLQSESRINMKLTASQWSAMVFVLLTSGQKLDVFDLNKYIGTYILPDESLQRLQPVLAASRTAKLCEHNLTKRGYSVLVSVLTSKTSCLRELNLTRSAVNDSGLKLLCSGLENPQCKLETLRLEFCGVSDKGCDFLASALRSNPSHLKALDLSGNTLNFTGLKNLLAEFQKPHCKLQRLCLRLCGLTDVGCDALASVLRSDPSHLTELNLSGNKLGDLGMKLLAGGLQNPHCKLQILRLGDCSITHEGCAALASALRSNPSHLRELDLSGNKLNNAGVQILSGELENPDCNLEILRLENCDVGEEGCAALAEALKSNPLTLKELDLCWNKLGNSGVQRLCTSLENPNCTLGVLRLTGCNISENGCAALASVLRSNPSYLRDLDLSHNDLRSSGVRLLSSALEKPDCKLEILRLEYCKITDDGCAVLASALKSNPSHLRELYLYMNSFNLTASGRQLLSKIKDDPHYKLQTLHYESHFFC", "length": 1074 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PCI8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTQTTIEKDYSPRFSLVHQKRSEPSCVSIRRDQSVAHPIDFKSEDTQTHLSSVHQERLDPEPSCVSIRSDRSVAHPIDFKSKNTHLSSVHQERSEPEPSCVSIRSDRSVAHPIDFKSEDTQTHLSTFHQKRKEADPSCVSMRSDTFMNQPINIKIGETQNDLKQNLLNTFRSNLLKKFECLYEGTAVQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQNKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSEKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCLNNNRNEFEQISKQSLWSKVRDHFHFNSSKLVSISKLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQGLMKLKIRSIQNNETVEYIKKKIRKINFPEKFINLFHCLNELGDHSLVEEIQQFLKSGGMNEAKLSSSQWSAVVFVLLTSEKKLEKFDINEFAARNNNTEQLFIFKKLQPVIRQCRSVQLSYCGLTDEGCAALASALRSNPEHLRDLYLSGNKLGDSVSLLSGVLEDPHCKLETLWLSDCGLTSKDSAALASALRSNPEHLRVLDLSWNRLGDSVTLLSAVLEDPHCKLETLLLRDCGLTDEGCAALASALRSNPEHLKHLDLSWSNLGDSVTLLSAVLEDPRCKLEKLGLSNCGLAEEGCAALASALRSNPEHLRGLNLSVNNLGDSVTLLSAVLEDPRCKLEKIKLSYCGLTDEGCAALASALRSNPEHLRDLDLSTNNLGDSVTLLSAILEDPHCKLEKLELKNCGLTDEGCAVLASALRSNPEHLRDLNLSWNNLSNSTKKLLSDLKDDPHNKLETLHTSLSV", "length": 1115 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PLT8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "nlrc8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSMNHPKHFKSGETQNDLGSAHQKRSDPEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQKRSDPEPSCVSMKSDWSMDPPMQFKSKDTPPDLSSVHQERSEPEPSCMSMNSDLPLDPPIRYKSGETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQSLWSKTKFMFKTVALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLKLKRRSIKNNKTVEYIKKKIRTIDSPEKSINLFHCLNELGDHSLVEEIQQYLKSGGINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAENNKTEKLVIFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTLLSAVLEDPHCKLEKLWLSYCGVTDEGCAALVSALRSNPEHLRELNLSGNNLGDSVTLLSAVLEDPHCKLEKLRLYYCGLTDEGCAALASALRSNPEHLRDLDLSWNKLGDSVTLLSAVLEDPRCKLEKLELYNCGLTDEGCAALASALRSNPEHLRDLNLSGNKLGDSVTLLSAVLEDPRCKLEKLWLSDCGLTDEGCAALASALRSNPEHLTELDLSWNNLSKSTVRLFSDLKDNPHNKLKTLHI", "length": 1017 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPT2-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSKRKREDEDAASEISSASPGSSCVSVKSDQSMKKNLPDFSDASVTSDLSISKTINQRSASPEFSVLSMTSNRSIGQPENFSDEPVTFDSVLSDALDKPDYEKLHRIKDQHKTSMKNKYERLFEGLKLDETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHRASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFHVFYYHVNTTMDGLRNFASVENLIKGAVDKAIESENGHLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLFREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCGIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTRQKLNWDHGGHFRITPGLRKYACFLTLDPNTAHNQLILSEDKRKVTHVKDPQQYTDYPEKFVHQEQVLCKETLTGRCYWEVEWSGEGTDIAVAYKGIRRKAGSDCWFGYSEKSWSLFYTGNGFNVWHNNKSQIIPAPSPLSNRVGVYLDTESGSLSFYSVSDTHTLTHLHTFNTTFTEPLYAGFRVFDSSLSLCNI", "length": 993 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PSD3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEEQGKMSLSEKHSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKPMSAKSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKQTSAKSVISDSCVSGSVFVKSDCSKDGDLPNFSEETPSSGKSFEHKTSDSDFQTHRKHKGFQDGLLGIFQDLENQIMNYLKHELEKFKKILQKENIIDFVKDFNENRCSIKEAALDLTLYFLREMKQEESADTLEDELIFIHQLKCGLQKKYQCVFEGIAQQGDSRLLKNIYTDLYITQGGSEQVNTEHEVRQIEVASRRHEAQELQVECRHLFEASEQDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQEISFIFPLPFREMNLKEKETLSLMELITQFFPETKGLNLTRRNRFKVLFILDGLDECRLPLNFAGNETCCDVSSPASLDVLLTNLIKGNLLPSALIWITSRPAAASKIPPDCIDRLTEIRGFNDAQKEEYFRKRLTDENQAKEIIDHVKQSKSLFIMCHIPVFCWISATVLQNILQEKRNNDVKHNQADDASKTLQESNTEDTPKTLTQMYTHFLRFQIQQSRRKYNGEYTPDVSWDKDAILSLGKLAFHHLLNNNLIFYDTDLEACGIDVYKASVYSGMCTQIFKEETGIILGTMYCFVHLTLQEFIAALYAHLILDTNKKSVFDQDSKKINESMIDLLKTAVDKALESDNGHLDLFLRFLLGLSLQSNRRILRGLLTPQDQDDQSTEKILQYIKQKFDANLSPERSINLFYCLNELNEQTLVKEIQTHLSKGSLSSADFSSAHWSALAFVLLTSDEEMEEFELQKFHKSDECLIRLSAVIKTCKRALLNDCNLTDRSCSALATVLESDTSLKELNMSNNNLQDSGVKLLCTGLKDMKCELEILRLSDCNITEEGYKALASALRSNPSHLLELDLRGNDPGESGVKELDDLLQDPNCTLKTLRFLSPSAEESCQFVNGVVGKNPLLLKTLNLNDFRSTRNHPFIYEIEDTQVNHLAALLQDKHCRVNMLILGGCSFTDDQWESLTSALKLNPSHLRELILMWNGPGESGVKILSDFLIEPQLKLEKLCLCYCSITEERCEILTSALKSNPSHLRELNLSQNIPGDSGMKNLSDLLMNPQSKLEKLQLCKCSITEEQCVILTSALKSNPSHLRDLNLSLNNLGDSGVKTLSDLLMKPHLKMEKLWLCKCSITEEQCVILASALKSNPSHLRELSLSENNLGDSGVKNLSDLLMKPQFKLEKLHLSHCSITEEQCEILTSALKSNPSHLRELDISKNQIRNTGVNLLCDVLNNSDCKLETLRLNDCGITDVSSLTQCLTNTKALQFLKVLYLRENHIGDSKQELSDVVRDSNCELSVDEFSLPDFGQIKDIKCCIS", "length": 1370 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCS9-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLQKKNEDEDEESASEMSYPPPESSCVSMKSDWSMVYPPDLSDASVTSDPNNSKRKGQHLEFKESSCVSVMSNRSITPPEMKKIGLKSEDNMLEKIKNKHKTSMKHKYERLFEGVKLHENQTLLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVGVSDASVYSGICTEIFKEESVIQQRKVYSFTHLSIQEFLAAFYVFYYHITCSTEACFDSLHDLQRRAVDKAIESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITSGLRKYACFLTLDPITAHTQLQLSEENRKASIVTDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGLVAVAYKGIGRKSGFDCCFGHNEHSWCLYCSDEVYSVWDNNKSVDVFGPSSRTNRVGVYVDVPSGCLSFYSVSDTNTLTHIHTFNTTFTEELYAGFKVYPGSSVSLCPVKPAEVPP", "length": 988 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUW9-1", "protein_name": "NLR family CARD domain-containing protein 3 isoform X1", "gene_name": "si:ch211-196h16.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKGNTGFRVKPPEPSGVSMKSDRSMHHPLKFKGGIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDPMFRPPEPSVSEKSGQSVDPTLKFSVHTCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDIGEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSINLFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQLDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLRLRCCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLCRCGVSDEGCAALVSVLSSNSSNLRELNLTENKVGDSGVKLLSAGLKENSKLEKLWLFICGVSDEGCAALASILRSNSSNLRELDLTGNKVGDSGVKLLSAGLKDPHCKLEKLTLDFCGVSDEGCAALASALRSNSSNLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC", "length": 1041 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32T552-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:ch73-50f9.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSGKHSVRSGSCVSRSVSLKSDESRKGLPPEFSEQPPSSNRSVEYELSDSVDKTHCNRKSFTDHLLRIFQDLESKIFKVLKNELERFRQILQGENTQDFVKGSNENQSSITKSALDLTLLFLREMKQDEVADTLENELLFINRLKSSLKKTYQSVSEGIAQQGDSTLLNNIYTDLYITQGANEQVNTEHEIRQIEAASRCHKSLEIQVECKHLFEAPEQDKQIRTVLTKGVAGIGKSVSVQKFVVDWAEGKANQDISLIFPLPFREMNLKEKEKQSLKDLITQLFPEVKGLNLTRRTRNKVLFILDGLDECRLPLNFAGNETCHDVSAPAYLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLADQNLAMEIIEHIKQSKSLHIMCHIPVFCWISATVLQNVLKETKVKHKACAKTLQESPKTLTQMYTHFLRFQMQQSRQKYDGKNTDGVSWDQNFILSLGKLAYQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKQETGIILGNLYCFLHLSIQEFIAALYGHLYLDIKKKSVFTGQKHKNKGMTHLLKTAVDKALESDNGHLDLYLRFLLGLSLQTNRQLLRGLLTQQDKSDQSKEEIVVYIKQKLEENLSPERAINLLYCLNELNDHSLMKEIQSHLRDGSLSSADLSPAQWSALTFVLLTSEEELDEFDLQKFKKSDECLIRLSAVIKSSKRALLQCCNLTAQSCESLSSALQSSNCVLRELELSNNDLQDSGVKLLSCGLRSLNCPLEILRLQCCNLTAQSCESLSLALQSSTCVLRELDLSNNDLQDSGVKLISNGLKSCKLEILRLSGCMVTETGCGFLSSALSSNPTHLRELDLSYNHPGVSGVKLLCQKLEDPNYTLAKLNVDHAGAKRITAGPRKWISHLTLDPNTANTELSLSAENREATRVIEKQPYPDHPDRFDYHPQVLCRESVCGPCYWEIDWSGDVGACISVSYKSVSSKGNDEFGCNDQSWSLSCYSSRFSYGHNNRWTDLPVKPISRRIGVYVDHRAETLRFYNICGNTVHLVHSVRTTFTQPLYAGFKIYPGSSVKLC", "length": 1099 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TA29-1", "protein_name": "NLR family CARD domain containing 9 isoform X3", "gene_name": "nlrc9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTKISKDEDYSPRFSSVHQERSDLEPSCVSMRSEQSMGSPMHFRSEDTEADLSSVYQKRSDPEPSCVSMRSDWSMDLPYNFRSEDTPTDLSSFHHKRTEAEFSRVSMRSDMFINHPINIKNVEAQCNIRQNLLNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFESAVRLCDISESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPMFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDEFEQIKKQSLWFKVKDLFQLNSLECVSLFSLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQRLMKLKSRSMQTNKTVKYIKMKIWTIDSPEKSINLFHCLNELGDHSLVKEIQQYLKSGRINRAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAGNNENKKQKVFQKLLPVIKQSRSVLLYNCGLTEMDWDNLTSALRSNPSDLRVLNLSRNILGNSVTLLSAVLEDPCSKLEKLWLSDCGLTDEGCAALATALRSNPEHLRELNLSWNNLRDSVTLLSAVLEDPRCKLETLWLSKCGITGKSCAVLASALRSNPEHLRDLDLSGNKLGDSVTLLSAVLEDPHCKLKILWLSDCGLTDEGCAALASALRSNPGQLRVLDLSENKLKNSGVMQLCAVLEDPHCKLDKLGLYDCSLTDEGCVALASALRSNPEHLRELDLSVNKLRDSGIKLLSAVLEDPRCKLEKLWLSNCGLTDEACAALASALRSNPEHLRELNLSKNKLGESDVKLLSDLKDDTHYKLKELNY", "length": 1079 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TJY6-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkeyp-100h4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQQIQETRLKGDTRASQTISSPSSSCSMAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKDCPPVFSGETPSSAQSVEFESADSGDETHRRHKSFTDNLQSIFQNLESKMFTFLKNELEKFKKILQENRQEIVKEFNENRSRITEAALDLTIFFLREMKQDQAADTLVGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVKCKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDDQKQEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGFVLHTMYCFLHLSIQEFIAALYQHLILDNDKTQAEKSRDESMIDLLKAAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEANLSPERSINLFYCLNELNDQSLLKQIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAIIKTSKRALLQGCYLTVPSCESLSSVLQSSNCVLRGLDLSNNDLQDSGVNLLSDGLKSQHCKLETLRLVMCNLTVESCESLSSVLQSSNFVLRELDLSNNDLQDSGVKLLSDGLKTVNCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVELLFEKLADPNYTLDKLNLDHGGHTRITAGPRKNACFLTLDPNTTYAFLILSEENREVKTVREYQLYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDDYVDISVSYKSIMRKGVDPECVFGRNAQSWSLCCDSSSFTFWHNDTDTRLPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLWPGFTVWCQSSVKLC", "length": 1125 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TMV3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like", "gene_name": "si:ch211-197e7.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDWSKEDPPKFSEKTPSSAQSVRSGSCVSSSVSLKSDRSKEHPLPNFREKTPSSAQSVEHELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNEMEKFKKILQEENRQEFVKDYNENRSRITEAALDLTLFFLREIKQDQAADTLQDELFSINQFQCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNNEHEIRQLEAASRRHQSLETQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNKTCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKILFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALENENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDESKKKIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFMLLTSEEELEEFELRKFQRSDECLIRLSAVIKTSKKALLQSCNVTVQSCKSLSKVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLAMCNLTVQCCESLSLALQSSNCVLRELDLSNNDLQDSGVKLLSNRLKSQYCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDKLNLDHGGEKRITAGLHKYVCFLTLDPNTAHIQLILSEENRKVKPVREDMMMMRKDQPYPDHPDRFDGLYPQVLCRESVCGCCYWETDWSGDGGVCISVSYKSIRRKGGVECEFGRNAQSWSLHCSSSRFIFIHNNTETRLPVKRLSKRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRVYSGSSVKLS", "length": 1140 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TPE7-1", "protein_name": "Protein NLRC3 isoform X4", "gene_name": "si:dkey-11n14.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKYSVRSGSSSSVSLKSDWSKDEPPKFSEKSPSSARSVEYELPYSGDKTHRSHKGFTKDLPRIFQNLESKIIRYLKNELEKFKKILQEENRQDFVKHFNENRSIITEAALDLTLFFLREMKQDEAADTLEGELFFINQLKCGLKKKYQNVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTTGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKENQSLKDLITQFFPQTKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTKLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISANVLLNILKENRNTELKHRDNSETLHESPKTLTQMYTHFLRFQIQHSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYDSDLKDCGIDVYKASVYSGMCTQIFWEETGIILGTMYCFLHLSIQEFIAALYQHLFLDSDKKHLSIFRQKSKNKVMTDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQNDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSADLSPAQWSAVAFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQGCNLNVRCCESLSSALQSSNCLLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDTLNLNHGGEKRITAGPRKYVCFFTLDPNTANTRLILSKKNREVKCVRENQSYPRHPDRFDDHPQVLCRESVCGRCYWEIDWSGGNEVCISVTYKSIRRKRGYECRFGYNAQSWSLICSSSRFSFTHNDTHTDLPVKPFSRRIGVFVDHCAGTLIFYNIYRDTMSLIHSVQTTFTEPLIPGFWVYSGSSVKLLKTEERFTQNPLQDQ", "length": 1060 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQ28-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:ch211-226o13.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTHTSGDLDLFTSCSVDGDDQTRDLQQDSLQPEHDELQRAKNQHKTSMKNKYERLFEGINHGETQKFLNRIYTQLYIIEGESEGVNREHDVLQIEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQGVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITARPAAAHQIPSTYIHRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDQEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFHCYLTDKREPVMLLYESKYSDDEDVSDGNEYEDSDVQFLQSSSEFSLCHLLSLAIYKAVMSSNGHLDLFLWFLLGVSLESNQRLFQDLLTHTEESSESIRIITQDIKDKIKTDDDLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSERELSPAHCSTISYMIEMSEEPLDELDFNKLNTSPVGRWRLIPAVRNCRRALLQWSYLSVQYCESLFSALKSSNCVLRELDLSTNDLQDSGVKLLSDGLKSPNCKLETLRLQCCNLTAQSCESLTSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCKLETLRLVMCNLTVQCCESLSLALQSSNCVLRELDLSNNGLQDSGVKLLSDGLKSQHCKLDTLRLVMCNLTVQSSESLSSALQSSNCVLRELDLSTNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGLHKYACFLTLDPNTTYAFLILSEENREVKRVREYQQYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDGCSVCTAVSYKSIRRKGRGAECLFGRNAQSWSLCCSSSSFIFRHNYTRTELPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFTVWCQSSVKLC", "length": 1145 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQA8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-29j8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEEQVKDSLSEKQSVRSGSCVSSSVSLKSDNSKGGRTPNFRGKTPSSVKRFFHLGKSKHPPSNLREKTPSSAESFQYELPDSRNKTHRSQKSFRGHLQKIFENLESKIIKFVKKELKNFRKILQNENRQEFVKEFNENSSGITEAALDLTLFFLREMKQDQAADTLQGELLYINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSVVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDTQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVLCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNKVMINLLKTAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQCCNLTVQCCESISSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQQCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGEKRITAGPHKYVCFLTLDPNTAHTRLILSEENREVKCVRENQPYPDHPHRFDYYLQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGAECAFGRNAQSWSLICSSSSFTFRHNNSHTDLTVKPLSRRIGVFVDHSAGTLIFYDIYRDTMSLIHSVQTTFTEPLCPGFYVSYGSSVKLS", "length": 1064 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TTK4-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAMNRLMTDMLEELVEAELKQFTRQLWMGVKPGVDPIPRGKLENKDRQDVVDCMVQHYSKDAGKIAVQALRSIKQNERADRLELNLRKDDDFLGEVLKKHKESIKASVDVFEGKKDNKTDINKVYTELFITEGDMTDVCKEHEVQKFDLALQMPRSEDKPIDCNEIFNLLRGKDKGNVVLTKGIAGIGKTFSVNKFILDWAEGRANLDVDCMFLLPFREINLMIKDGDVSLHKFLLKLFPDITGVETTPFYEKCKLLFIFDGLDESRLDLNFNLSSVDDVHSCASIDGLFTSLIKGRLLRSSLIWVTSRPAAANRIPSYHVGLFTEVRGFTDKQKEEYFRKKVPDEDQASRIISHIRTSRSLYIMCHIPVFCWIIATVLQDILQKNKGEDIPSTLTEMYIHFLLIQMNIKNQKYDEKLIRDRTELLGSNRDMISKLAKLAFEQLKKENVMFYREDLAACGINADEEFTGLCTEIFKKDSVLHELKVYYFIHLSVQEFLAALHVFLCYLELEKDMNLTDSDLMFFLEDSRPKQKELLHVLLRKAIDKAEKSDRGHFDLFLRFLLGISLESNQKLLIGILNETKNSKQSISKTVQYLKQLQNNDKCPDKSINHFFCILELQDRTLYQQIMKYLRSKTNRPKVMSRSNCSALVYVLLMSQEVLDKFNPKLFNKTYAGCRILVPAVRCSRKALFSDCGLTETCFETVALALQLENCPLVELDLSYNYSLEAAVNVMCAGLKSPHCHLESLRLAGCHLGQDSCMQVVSALQSISHRLKELDLSGNDLQDSGLQKLLQGMENTEKRLQVLRLSWCNLTEMSCQQLSTILSSNSVFRELDLSNNDLQDSGVKLLSDGLKSPNCKLKILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHCKLKTLKTDPMGDHLMKPGIVKYAFNLTLNPNTAHVHLLLSDGDRKVTLKEKQPYPDDPERFEEHHQVLSRESLSGRCYWETEWTGQEGTVGVAYESIPRKPDDLLYGRCMLGNNIISWKITCGSRTHVSHAEEDITVKSPSSGSCKRVGVYVDTTAGVLSFYHVFDTLTHLYTFLMPFTQPLYAAFRVDGESVSICPIP", "length": 1114 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TUF4-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch73-236c18.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHHCGNEEVDREEKEKHGAEHSCVSMKSDQSMRNPIAFTDKAVTFDLRSVASSSSHFETHTVQEKTDKGLQTQIFETEELQRVKDQHKTSMRKKYELLSEGIKVKETGTQLNRIYTQLYIIEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFYVFYYHVNTTMMGLKTFASLQKLLKGAVDDAIESKNGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCRLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRIKPGLKKYACFLTLDPNTAHVQIQLSEGNREARNVKDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYCCDTNYTVWYNNESADIIAPSARTNRVGVYLDVSSGSLSFYTVSDANTLTLIHTFNTTFTEPLYTGFGLYPESSVSLCQI", "length": 969 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HZJ9-1", "protein_name": "Uncharacterized protein si:ch211-149a19.3 isoform X1", "gene_name": "si:ch211-149a19.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDKEASNDGDFSSRRSHFQSQKSNTSESNPEITPEDLSAKKLIKMFEKRTPDNQSKFNNQKSNTAKSIRSDRSIQNPVKIKEIRTPADLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPKPMPRSIKSDQSTPELDKVDGGHTSTALSSQRSNPPDPKPRSIKSDQSTPEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGIGCQRSNPPDPKPRSIKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPESSLVSLKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSMPEPIKFDGGHTPTGLSETSTNDQFMNKQVKIKRRHTLTGLSKTSINYQFMEKQLKTERRHTSTGLSLNSKLFENLLKSNLLKKFQCVSEGTSILGNPTLLNEIYTELYITESDSGEINNEHELRQIETQSRRSAKEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEKNKNQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEHYKVLFIFDGLDECRVSLDFDSGVKLHDVSESASVDVLLMNLIMGNLLPSALIWITSRPAAADLIPSGFVHRVTEVRGFNDPQKEEYFRKRIRDQSLADTIISHLKSSRSLHIMCHIPVFCWISATVLEKIFSQAERGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEDKDMILKLGKLAFEQLQKGNLIFYEEDLRECGLDLTEAAVYSGLCTQIFREEFGFSQSKVFCFVHLSIQEHLAALYAHHFLTNNCLNKHWKTFNPLSFLHQRAVNEALQSKNGHLDLFLRFLLGLSLEFNQTLLQELLTQTGSCSYNTEETVQFIKQKIREINSPERSINLFHCLNELGDQSLMKEIQNYLRSGEIKETKLSSSQWSALVYVLLTSEQEMEDFDLNQFIGTQNTADEVLQKLQPVVKESRSVQLSGCSVTDKGCAALALVLRSDSSHLRELDLSENNLRDSGVKLLSDGLKDPHCKLEKLRLSDCGVTDEGCAALASALRSNSTHLTELDLSLNNLEDSGVKLLSDGLKDPHCKLEILRLSDCGVTVEGCADLASALRSNSTHLRELDLTLNNLEDSGVNLLSAGLKDPHCKLEKLRLSDCGFTDEGCADLASALRSNSTHLTELDLSLNNFGDSGVKLLSDGLKDPHCKLEKLRLSYCRVRAEGGVALASALRSNPEHLRELDLSENKLGNSGVKMLSELKNDSRYKLDTLKF", "length": 1375 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCJ8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12-like isoform X1", "gene_name": "si:dkeyp-77c4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKEEHLPNFREKTPPSAQSVRSGSCVSSSVSLKSDWSKRDPPNFREKTPSSAKSSVHQKRAEAEPSCVSMKSDWSMNRPITFRSKITQPAISVDRDDQTGHLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSAQKFILDWAEEKDHQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCALTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQIHMRKQKYEERDPEKLLQSNRGVILKLAEVAFSQLMKGNVMFHEEDLTESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVLYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESTESIRRITQHIKDKIKRDKRLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDELDFNKLNTSAEGRRRLTAAVRNCRRALLQGCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLQWCKPTVQSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLVMCNLTVQCCESLSSALQSSNYVLRELDLSNNDLQDSGVKKLSDGLKSPNCKLETLRLVMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKRNCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKWVCFLTLDPNTAHTQLILSEENREVKRVRENQPYPYHPDRFDVHRQVLCRESVCGRCYWEIDWSGDVGVCISVSYKSIRRKGRGVECWFGYNAQSWSLICSSSRFSFRHNHTDTDLPVEPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFTVYSGSSVKLS", "length": 1235 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCK2-1", "protein_name": "Uncharacterized protein si:dkey-26m3.3 isoform X1", "gene_name": "si:dkey-26m3.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGYVFVLSSLCPVFILLQFLLEFLLEIKLFRSIMGNTHAAGDQDLSTECSSVHQKRAEAEPSCVSMKSDASMGVPITFKSENTGPAVSSVHQKRAEAELSCVSMKSDASMNPPIEFKSGNTGPAVSVDRDGQTGDLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEQIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKDNQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPKLEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTEPSSVAVLMRSLLKGDLLPSALIWITSRPAAAHQIPSTYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLDSNQRLFQDLLTHTEESSENIRRITQYIKDEIKRGKHLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELTPAHCSTISYMIEMSEEPLDELDSNKFNTSDVGRRRLIAAVRNCRRALLQRCELTVQCCESLSSALQSSNCVLRELDLSNNDLQDSAVKLLSDGLKSQHCKLETLRLMTCKLTADSCESLSSALQSSNCVLRELDLSNNDLPDSGVKLLSDGLKSQHCKLETLRLQWCKLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLAMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKTVDCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKYVCFLTLDPNTANTRLILSEENREVKHVRENQPYPDHPDRFDGVYQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGVECWFGSNAQSWSLSCSSSNFSFRHNNTRTDLPVKALNRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRIYPGSSVKLS", "length": 1239 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCL0-1", "protein_name": "Uncharacterized protein si:dkey-165o8.1 isoform X1", "gene_name": "si:dkey-165o8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDQSKDHPPYFREETPSSAESVEYESADPGDETHRRHKSFTDNLQSIFQNLESKIIRFLKNELEKFKKILQEENRKEFIKEFIENRSIITEAALDLTLFFLREMKQDQAADTLQDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNKIYTDLYITQGASEQLNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCGDVSSAVSLDVLLTNLIMGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILRLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLDRNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLDIDKKRGWFLIQISKNKSMIDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQFCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKCRTTHTQTHTHTHTHIHTHTHTHTHIHTHTHTHTHTHTRAHTHTHTRGLQQDRANVGPHTYTHTHTHTHTYTYTHTHTHTHTHTHTHTRITAGPRKCRTTHTHTHTYTHTHTHTITHTHLHIHTHTCTHTHTCAHTHTHIHTHTLTHTRTYTHTHTHTLPLTHTHTHTLSHTHTHTHTNIHTHSLTHTNIHTHSLTHTNKHTHSLSHAYTHACMHALSHLHTHTHALTHTHTHTHTHSLTHTHICTHKHTHTLSHSHKHSHTHTHTHTHTHTHTQARAHLHKHTLSHTHTHIHIYTHTYKHTHILSHTHAHTHTHTQARALTQTYSLTHTHTHTHKHTLSHTHTHIHHTHTQIHIHSHKTHTHARTHTLSLSLTHTHTHTHTHTHTHTHTHTHTHTQLWL", "length": 1266 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z7N0-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Dmel\\CG8197", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCDVLLPCEYNPKECPSPAAEKSRLFTILLLYCWQREYDKRPYRQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLRRPQLSVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPREFFVMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANRLLGMSLSLDTEKISSVLSSLLMQNTLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLAMKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISYTYDEALQDYRVVPWR", "length": 387 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZAD9-1", "protein_name": "NLR family, pyrin domain containing 9", "gene_name": "Nlrp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDTSGYGLLKHLRKLSDGEFWSFKELLRKEPEKFKLKPISWMKIENASKEELVMLLNTHYPKQAWDMALSLFLQVNREDLSIMAQKKRRYKQTKYKKFMKTTFQSIWTLESNICIPDRSYHLIVEHQYRKLQNIFDSESEPVTAVVTGPTGEGKTVFLRKAMLDWASGILWQNRFQYVFFFSVLSLNNTTELSLAELISSKLPESSETLNDILSDPKKILFILDGFDYLKFDLELRTNLCNDWRKILPTQIILSSLLQKIMLPESSLLLELGHISLPKIFPLLQYPRDITIQGFSERCLKTYFISFFNTEKGIEVFENLKSNQMLKLCSNPYLCWMFCSCLKWQFDREEEAYFQAKTDSVFFTSFMVSAFKSAYASNPPKQNRAQLKSLCTLAVEGMWKQLFVFDSEDLRRNGISESDKAVWLRMKFLQNHDNHIVFYHPTLQLYFASMFYFLKQDKDTHVPVIGSIPQLLRKIYARDHTQWLQIGIFLFGLATEQVASLLKPYFGFIQHRDVRQEVMRYLKSLSQRECCEKLERPQNLFACLRDNKEEKFVREVVDLFEEITVDITNSHVLSIIANHLQKSSKLKKLHLHIQKRVFLEIHDPEYSDSETFTQDKKNAAEYWKKLCHIFVNLHVLDLDSCNFNKQVIEELCNVLSPSPKIPLMAFKLESLLCSFMTNFGDGSLFHTLLQLPHLKYLNLYGTNLSNSRIENLCSALRRSTCKVEELLHSEMSFPLSTDFIVSHKFGLGKCDISSEACGIIATSLMNSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLETLMLSYCCLTFIACGHLYEALVSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCILKELWLSGCFLTSECCEEISAVLTCNNNLKTLKLGNNDIEDTGVKHLCEALSHPNCKLECLGLDLCKFTSDCCEDLASALTTCKTLNSLNLDWKTLEHSGVVALCEALNHKKCNLKMLGLDKSAFSVESQTLLQAVEKKNNNLSILHYPWVEEERKKRGVRLVWNSKN", "length": 1022 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZP31-1", "protein_name": "NLR family, pyrin domain containing 4", "gene_name": "Nlrp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEILQLRLKQISWTKVKKASREDLANLLLKHYEEKQAWDMTFKIFQKMNRKDLIERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKAQDLFKQKFTQDDCDRFENLLVSKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGIVFQNKFSYIFYFCCQDVKQLKRASLAELISREWPNASAPTAEILSQPEKLLFIIDSLEVMECNMSERESELCDNCTEKQPVSLLLSSLLRRKMLPESSFLISATPETFEKMEDRIECTNVKIITGFNENNIKMYFRSLFQDKNRTLEAFSLVRENEQLFNVCQVPVLCWMVATCIKKEIEKGRDPVFICRRTTSLYTTHIFNLFTPQNAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFSEEALRRNGILDSDIPTLLDRRILERSKESESCYIFLHPSLQEVCAAVFYLLKSHLDHPSQDVKSVEALLFTFLKKAKVQWIFLGCFLFGLLHESEQEKLEMFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEAFLMQAMNCMEQINFVAKDYSDVIVAAYCLKHCSTLKKLSFSTQNILSEEQEHSYTEKLLICWHHMCSVLISSKDIHVLQVKDTNLNETAFWVLYNHLKYPSCTLKVLVVNNVTFLCDNHLFFELIQNQRLQHLNLSLTFLSHSDVKLLCDVLNQAECNIEKLMIAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLCKALCHPDCILKHLVLANCSLSEQCWDYLSEVVRRNKTLSHLDISSNDLKDEGLKVLCGALTLPDSGLISLSVRHCLITTSGCQDLAEVLRHNQNLRSLQVSNNKIEDAGVKLLCDAIKQPNCHLENIGLEACELTGACCKDLASAFVHCKTLWGINLLENALDHSGLVVLFEALKQQKCTLHVLGLRITDFDKETQEFLIAEEEKNPYLSILSNV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZUH1-1", "protein_name": "NLR family, pyrin domain containing 4A", "gene_name": "Nlrp4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLGLKQVSWTEVKKASREDLASLLLKHYEEKQAWDMTFNFFQKINRKDLIKRAKREIDGYPKLYRAHLKTKLTHDSSRIFNINIQDFLKEKFTKDDHDRFETLLQSKGTESKPQVVVLSGVAGIGKTLMLKRLMLAWIEGLVFPYKFSYIFYFCCQEVKQLKTASLAELISREWPDPSAPIEEILSEPEKLLFIIDSLEGIECDLFKCDSELCDNCMEKQPVNILLSSLLRKKMLLEASLLISTTPETFEKMEDRIEYTHVKIITGLNESDIKMCFHRLFQDRNRAQEAFSLVRENEQMLTICQVPVLCWMVATCLKTEIEKGRNLVSTCRRTTSLYTTYIFNLFIPQSAHSPSKKSQDQLQGLCSLAAEGIWTDTFVFTEEALRRNGILDSDIPTLLDIGMLGKMGKFENCYIFLHPSLQEACAAIFYLLKSHGDHPIEDVKSVEALLFTFLKKAKVQWILGGRFIFGLLHESEQKKLEAFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEDFLMEAMNYMEQINFVAKDYSDVIVAAYCLKHCYTLKKLSFSTQNILNEEHEHSCMENLLTCWRHICSVLINSKDIQELQIKDTNLNEPAFSVLYNSLKYCNDTLKVLVENNVFFLCEKYLFFELIQNCNLQHLNLNLTFLSHSDVKLLCDVLNQAECNIEKLEVAACNLSPDDCKMFASILMSSKTLKQLNLSSNILGKGISSLCKSLCHPDCILEHLVLAKCSLSDQCWDYLSDGIRQNKTLNHLDISSNDLKDEGLKVLCRALALPNSVLKSLCLRHCLITTSGCQDLAEVLRNNQNLTSLQISYNKIEDAGVKLLCDAIKQPNCHLEDLGLEACELTGACCEDLASTFTQCRTLWGINLLNNTLDYTGLVVLCEALRQQKCTPHVLGLRITDFDNETQAFLVAEQEKNPDLSILSGV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A1P8-1", "protein_name": "NLR family, pyrin domain containing 4B", "gene_name": "Nlrp4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLFSDFGFMWYWKELNKVEFMKFKELLILEILQMGLKQISWTEVKNASREDLAILLVKYCEGKQAWDTTFKVLQKISRHDLTERATGEIAAHANIYRAHLKKKLTRDCSRKFSISIQNFFQDEYDHLENLLIPKVTEEKPQLVFLKGIAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCQDVKQLKTTSLTELISREWPSSSAPIEEILSQPEKLLFIIDSLEGMEWDFTKQESELCDNCLEKQPVNVLLSSLLKKKILPESSLLISATFETFEELKDWIEYTNVRTITGFKESNIKMYFHSLFQDRNRALEAFSFVRENEQLFTLCQAPVICCMVATCLKNEIEKGKDPVSICRRTTSLYTTHIFNLFIPPNVQYPSKKSQDQLQGLCFLAVEGMWTDISVFSEETLRRNGILDSDIPTLLDIGILEQSRESQNSYIFFHPSVQEFCAAMFYLLQTHMNHPSPDVLHVEKLLFSFLKEVNTQWIFLGRFIFGLLNELEHEKLEAFFGYQLSQQLKQELFEWLELLLDPEVKVNTMKFFYCLFEMEEEVFVQSAMNCREEIDVVAKDYYDFIVAAYCLNHGSALRDLSISTQNVLNEKLNQRYMENLLMLWHNICSVFARNKDIHILQMKDTIFNEPVFQILYNYLKNSSCILEVLVANDVSFLCDKYLFFDLIQSYNLELLDLSGTFLSHSDVVILCNILNKAEYKIQELELANCSLSEQSWKYISDVLCQNKTLRHLDISSNDLKDEGLKVLCKALTLPDSVLLTLSVKACFITTVGCQYLAEVLRNNHKLMFLTLSENKLEDSGVKLLCDAIKHPRCQLAQLDLEACELTGACCEDLASTFTQCKTLGWINLVKNALDFNGLVVLCKALKQKTSNLKELRLRITDFDNKSQTFLLSEEKGNKFLNIENDE", "length": 918 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A523-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWNDACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGRTKMWDRPMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEEEEKRGSQPLDQVQCVFPDPHVACSSRLVNCCLTSSFCRGLFSSLSTNQSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSSQKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTNQNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNCETKRTLEALQEEKPELTVVFEISW", "length": 1035 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FA88-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "nlrc11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYCNYNMDNTRSSRDEDIYSCTSRESEEVLSNTSYWSLPSYFRHRKFHRSSVHEKISDSSESSRVSLKSDWSMNPPPLLGEERKSSNLNMSSLVSVRSDWSMDPPPLLRAKGKSAVSSGVSDNIDWLVCSPYLRVERKSSALRHKLSLLKKFQCLYEGTAVQGKPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLIKDKKFSLVSLLQTFFTREIHLDMIQNSAVIFIFDGLDECRLPFNFSRNEILLDVTKETSVDVLLTNLIVGNLLPYALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILRLGKLAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLLFTNHNINVFEQMTKSFEGTPLNKSDLQSLTLNMELFEISEPVLTDVAAMCEMDWRVVNEISALHCKAVDEVLQNKNGHLDLFLRFLLGLSVECNQILLQRLTKQRRHLYNDNKTVEYIKKKIRTINSPEKSISLFHCLNELGDHSLVEEIQQYLTSGKIKEFKLSSSQWSAVAFVLLTSEKKLEEFWLKEFVGAETKADHVLQKLLPVVKESRKAELSKCGLTEECCAALASALRSKLSHVRELDLSGNKLGDSGIENLSTGLENLHCKLEILRLRSCGITAKGCTALASALRSNPEQIRQLDLSENNIRDWGVKHLFTELKNPDCKLEILGLRNCGITIEGCAALTSALIINPSHLRELDISRNSLGDTGQELLTSLLNSQHHKLEILLLHKFPMTFTSLPSSHSPEMFPQRFRTHNLKE", "length": 966 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q5R7-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSTARDGLYRLSTYLEELEAGELKKFKLFLGIAEDLSQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGEDLVRVTPNNGLCLFESQSACPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPEPPHTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGPWCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTPRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFAAMYCALNGREAVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWSISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQVVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGSAYSTGMEDDPPEPSGVQTQSTYLQERNMLPDVYSAYLSAAVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISGSACQDLAAAVIANRNLIRLDLSDNSIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLSNNSYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVNTCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGISQTLHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFGMDLNKKTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M918-1", "protein_name": "NLR family, pyrin domain containing 14", "gene_name": "Nlrp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTEDEEMEDQLSKEEIVSEDKEFDYRTIIKENFFIIWDKTSLLGESATLNCVTTHKDQKLLEHIFDVNIQTSKSPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLSGREISQEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFALCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMTCQTSTALFTYYICSLFPRIAGSSVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQDTECENCYTFTHLQVQEYFAALFYLLRENPEEKDHPLEPFENVHLLLESNHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLTISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVKVDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDPTAEICLEDAAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLNSCYDFSFLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQSNRSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTKTKRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNNKSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNNSNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNNQSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCPNTESGCWWQYF", "length": 990 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RA38-1", "protein_name": "NLR family pyrin domain containing 2", "gene_name": "Nlrp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHSDQLGFNLKDVLKKLDKTELNNFKSTLKSCSLPQTMKQISKLTMDLANGAQLAEILTDYCPNDWVKRVTFKILEEINRADLAELVMKQVEEAASKASEEKVSSKPREPLKTSLFPQDFVQGDERPEHKHKKEWRNMYTEKWKKNFWPKCNKEIYVDTESYRTLLTLCNPKIEMPFAYTIVLHGPPGSGKTTMARRLMLEWSESKQAQSFSCAFYISCRKLNNSKPCTFAHLLSMNNPSWRYYMIRRLVLSEQFLFVVDGFDELTFPAGALLRDICGDWNTVKPVEVLLSSLLMRKMEPHSTLLVTTQTQSLHQIYLMVDQPVLVETQGFLEPEKQEYFQQYFEDEEGEEEGEGEGKALRALKEVKCNEALFQMASLPAACGIFCLCLELGMKKGEDLALTCQTYTSMFLNFLCRVFLQEACDGHLNKQLQILFKKICILAADSLLEQVPILCEEDFLKLKLNLNKLHPVVYRCIFLEDSSCTNCLSFICLSIQQLLAAIIFVQELGQESKDVSKYSIQKMLSREARLKNPNLSGVLPFVFSLLNKTHIQELETIFGCQISMGVKRKFLECELGENKPFLLLMDLQEIFSCLYESQEEEFVKEAMALFGEVSLHLKTNMDLVHASFCLKNSQNLQTMFLKVEKAVFPENFATLESTAEDQRFQDKKCMLTLWTDFCDTFHSNEKLAFLEIHESFLNSSSLEILCEKLSSAPCHLQKVVLKNISPDDAYEKLCLIFCGYETISHLTLQGGKLDSMLHSLCKVVKNPACNLKFLSLGSCSTTAQKWDDFFPALKANQSLISLDLTDNNLLDKGVRLLCNTWKQSKCILQRVSLENCHLTEVCCKDLSSVLMVSQTLTHLSLAKNELGDNGVKKLCESLSFPKCKLQTLVLWSCNITSNGCHYLSKMLGQAPSLKHLDLGLNRIGTTGAKFLCEALKSPRSNLKSLWLCGCSIIPTNCKDFSEILRSNKSLNTLDLSQNVMGTDAVKIFCESLKLQICPLQTLRLKFDEANPSIQKLIQEMKESHPQLSITSDQVDPKKKSHSFPHFIF", "length": 1048 }, "evidence": [ { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P59046-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "NLRP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQSTCLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELKPSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEGEGGAGPDQDVTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSAGAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIANKNLTRMDLSGNGVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC", "length": 1061 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TKR3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4C", "gene_name": "Nlrp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLRLKQISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRKDLMERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKVQDFSKQKFTQDDYDRFENFLISKVTAKKPHMVFLQGAAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPKTSAPIEDILSQPEKLLFVIDNLEVMECDMSERESELCDTCTEKQPVRILLSSLLRRKMLPKSSFLISATPETFEKMEGRVECTNVKIVTGFNESNIKMYFRSLFQDKTKTQEIFSLVKENQQLFTVCQVPVLCWMVATCLKKEIEKGRDLVSVCRRTTSLYTTHIFNLFIPQSAQYPSKESQAQLQSLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPTLLDVRILEKSKKSEKSYIFLHPSIQEVCAAIFYLLKSHMDHPSQDVKSIEALIFTFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQVDGMKLFYCLFEMDDEAFLAQAMNCMEQINFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNVLSEGQEHSYTEKLLMCWHHMCSVLISSKDIYILQVKNTNLNETASLVLYSHLMYPSCTLKALVVNNVTFLCDNRLFFELIQNQCLQHLDLNLTFLSHGDVKLLCDVLSQEECNIEKLMVAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLVNCSLSEQCWDYLSEVLRRNKTLNHLDISSNDLKDEGLKVLCGALSLPDSVLKSLSVRYCLITTSGCQDLAEVLRKNQNLRNLQVSNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASAFTHCKTLWGINLQENALDHSGLIVLFEALKQQQCTLHVLGLRITDFDKETQELLMAEEEKNPHLSILSSV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X03-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9A", "gene_name": "Nlrp9a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDSSGYGLLQYLQKLSDEEFQRFKEHLRKEPEKFKLKPISWTKIKNTSKEDLVMQLYTHYPGKAWDMVLSLFLQVNREDLSTMAQTERRDKQTKYKEFMKNTFQHIWTMETNTYIPDRSYHEFIEVQYRALQDIFDCESEPVTVVVSGSRGGGKTTFLRKAMLDWASRNLLQNRFQYVFHFSVFSLNNITELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKKLPIQIVLSSLLQKIMLPECSLLLELGNASLSNIIPLLQYPREIIMSGFSEQTIEIYCVSFFNTQTGVEIFKNLKSIKPLFNLCRCPHLCWMICSTIKWQYERREVASRFGRTLGLLYTIFMVSAFKSTYARNPSKQNRARIRTLCTLAVEGMWKQVYVFDSDDLRRNGISESDKKVWLRMKFLQNQGSNIVFYHSTLQWYFAVLFYFLQYKDTRHPVIGNLAQLLGEIYAHKQNQWFHTRILLFGMATEQVNSLLEPCFGCISSKEVRQEIIRYIKSLSQQECNEKLVVHPQNLFFCILDNQEERFVRQLMDRFEEMTVDISDVDDMSATPYCLHRAPKVKNLHLHIQKRVFLEIHDPEYGDLELFKLGQKCSFTTNFGDGLLFCTFLHLPHLKYMNLYGTNLSNDAVERLCSALKFSTCGVEELLLGKCDISSEACGIIAASLINSEVKHLSLVENPLKNKGVMSLCEMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNEHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCYLTSECCEEISAVLTCNTNLKTLKLGNNNIQDTGVKRLCEALCHPNCEMQCLGLDMCDFTSDCCEDLALVLTTCNTLKSLNLDWNAFDHSGLEMLCKALNHKACNLEVLGLDKSLFSEESQTLLQAVEKKNKNLKVLHFPWLKEELEKRGVRLVWNSKN", "length": 949 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X05-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4F", "gene_name": "Nlrp4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFISDFGLIWYLRELNKKEFMKFKDFLIQEILELKLKQVSSTKVKKASREDLANLLLKCGENQAWDMTFRILQKINRKDLTERATGAIVGNPNLYRDHLKKKLTHDCPKKFNVRIQDFIKETFIQNDXDAFENLLISKGTERKPHMVFLKGMAGVGKTLMLKNLMLAWSKGLVFQNKFSYAFYFCCQDVKQLKTASLAELISREWPSPSAPIEEILSQPEKLLFIIDSLEGMEWDLTKQESELCDDCMEKQPVSTLLSSLLRRKMLPESSLLLSTTPETFEKMEDRIQCTDVKTATAFDERSMKIYFHRLFQDRKRAQEAFSLVRENKQLFTICQVPLLCWMVATCLKEEIEKGGDPVSLCRRTTSLYTTHIFSLFIPQSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFGKEALRRNGIFDSDIPTLLDIGMLGKIREFENSYIFLHPSVQEVCAAIFYMLKRHVEHPSQDVKNIETVLFMFLKKVKTQWIFLGCFIFGLLQKSEQEKLGVFFGHRLSKNIHHKLYQCLETLSGNAELQEQIDGMRLFSCLFEMEDEAFLVKAMNCMQQINFVAKNYSDFIVAAYCLKHCSTLKKLSFSTENVLNEGDQSYMEELLICWNNMCSVFVRSKDIQELRIKDTNFNEPAIRVLYESLKYPSFTLNKLVANNVSFGDNHVLFELIQNSSLQYLDLSCSFLSHNEVKLLCDILNQAECNIEKLMIAHCKLSPDDCKIFGSILMSSKSLKVLNLASNNLNQGISSLCKALCHPHCTLEYLVPRSNHCIVNFLLKLSCCGITERGCQDLAEVLKNNQNLKYLHVSYNKLKDTGVMLLCDAIKHPNCHLKDLQLEACEITDASNEELCYAFMQCETLQTLNLMGNAFEVSRMVFFPRKSELMLFIFLHLSRLWITDFDNEFQAFLLSVKKKNHFLTIRGSVEADGEKKGGDSDARTMGELSNEI", "length": 959 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X19-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4E", "gene_name": "Nlrp4e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKELLQQEILQLGLKHISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRQDLMERAGREIAGHSKLYQVHLKKKLTHDYARKFNIKDQDSLKQKFTQDDCDHFENLLISKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPNASAPIEEILSQPEKLLFVIDNLEVMECDMSEWESELCDDCMEKQPVNILMSSLLRRKMLPESSFLVSATPETFEKIEDRIECTNVKMMAGFNESSIKVYFYSLFQDRNRTQEIFSLVRENEQLFSVCQVPVLCWMVATCLKKEIEKGRDPVSICRRITSLYTTYIFNLFIPHSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFAEEALRRNGIMDSDISTLLDVRILEKSKESEKSYIFLHPSIQEVCAAIFHLLKSHVDHPSQDVKSIEALIFTFLKKVKIQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNKELQEQIDGMKLFYCLFEMDDEAFLPQVMNCMEQIKFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNILSEGQEHSYTEKLLICWHHVCSVLTSSKDIHVLQVKDTNFNERAFLVLYSHLKYPSCILKVLEVNNVTLLCDNRLLFELIQNQRLQLLNLSLTFLSHNDVKLLCDVLNQAECNIEKLMVADCNLSPDDCKVFVSVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLAKCSLSEECWHYLSEVLRRNKTLTHLDISFNDLKDEGLKVLCGALTLPDSVLISLSVRYCLITTSGCQDLAEVLRNNQNLRNLQISNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASSFTHCKTLLGINLQENALDHSGLVALFEAMKQQQCTVNLRGLRITDFDKETQEFLMAEKEKNPYLSI", "length": 978 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X22-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9B", "gene_name": "Nlrp9b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSSGYGLLKLLQKLSDEEFQRFKELLREEPEKFKLKPISWTKIENSSKESLVTLLNTHYPGQAWNMMLSLFLQVNREDLSIMAQKKKRHKQTKYKKFMKTTFERIWTLETNTHIPDRNYHLIVEVQYKALQEIFDSESEPVTAIVAGTTGEGKTTFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKRLPTQIVLSSLLQKIMLPGCSLLLELGQISVPKIRHLLKYPRVITMQGFSERSVEFYCMSFFDNQRGIEVAENLRNNEVLHLCSNPYLCWMFCSCLKWQFDREEEGYFKAKTDAAFFTNFMVSAFKSTYAHSPSKQNRARLKTLCTLAVEGMWKELFVFDSEDLRRNGISESDKAVWLKMQFLQTHGNHTVFYHPTLQSYFAAMFYFLKQDKDICVPVIGSIPQLLGNMYARGQTQWLQLGTFLFGLINEQVAALLQPCFGFIQPIYVRQEIICYFKCLGQQECNEKLERSQTLFSCLRDSQEERFVRQVVDLLEEITVDISSSDVLSVTAYALQKSSKLKKLHLHIQKTVFSEIYCPDHCKTRTSIGKRRNTAEYWKTLCGIFCNLYVLDLDSCQFNKRAIQDLCNSMSPTPTVPLTAFKLQSLSCSFMADFGDGSLFHTLLQLPHLKYLNLYGTYLSMDVTEKLCAALRCSACRVEELLLGKCGISSKACGIIAISLINSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLQSLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCFLTSQCCEEISAVLICNRNLKTLKLGNNNIQDTGVRQLCEALSHPNCNLECLGLDLCEFTSDCCKDLALALTTCKTLNSLNLDWKTLDHSGLVVLCEALNHKRCNLKMLGLDKSAFSEESQTLLQDVEKKNNNLNILHHPWFEAERNKRGTRLVWNSRN", "length": 1003 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6B966-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "Nlrp14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTEDDEMEYEASKEETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITPKDQNLLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLNGKEISQVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFALCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVGCVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQDTEYENCYMFTHLHVQEFFAALFYLLRENLEEQDYPSEPFENLYLLLESNHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVRVDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLDTAEMCLEGAAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLNGCQDFTFLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTKSKRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHNRSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNNSNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNNKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECPNTESGCWWNYF", "length": 993 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTR0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9", "gene_name": "NLRP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESFFSDFGLLWYLKELRKEEFWKFKELLKQPLEKFELKPIPWAELKKASKEDVAKLLDKHYPGKQAWEVTLNLFLQINRKDLWTKAQEEMRNKLNPYRKHMKETFQLIWEKETCLHVPEHFYKETMKNEYKELNDAYTAAARRHTVVLEGPDGIGKTTLLRKVMLDWAEGNLWKDRFTFVFFLNVCEMNGIAETSLLELLSRDWPESSEKIEDIFSQPERILFIMDGFEQLKFNLQLKADLSDDWRQRQPMPIILSSLLQKKMLPESSLLIALGKLAMQKHYFMLRHPKLIKLLGFSESEKKSYFSYFFGEKSKALKVFNFVRDNGPLFILCHNPFTCWLVCTCVKQRLERGEDLEINSQNTTYLYASFLTTVFKAGSQSFPPKVNRARLKSLCALAAEGIWTYTFVFSHGDLRRNGLSESEGVMWVGMRLLQRRGDCFAFMHLCIQEFCAAMFYLLKRPKDDPNPAIGSITQLVRASVVQPQTLLTQVGIFMFGISTEEIVSMLETSFGFPLSKDLKQEITQCLESLSQCEADREAIAFQELFIGLFETQEKEFVTKVMNFFEEVFIYIGNIEHLVIASFCLKHCQHLTTLRMCVENIFPDDSGCISDYNEKLVYWRELCSMFITNKNFQILDMENTSLDDPSLAILCKALAQPVCKLRKLIFTSVYFGHDSELFKAVLHNPHLKLLSLYGTSLSQSDIRHLCETLKHPMCKIEELILGKCDISSEVCEDIASVLACNSKLKHLSLVENPLRDEGMTLLCEALKHSHCALERLMLMYCCLTSVSCDSISEVLLCSKSLSLLDLGSNALEDNGVASLCAALKHPGCSIRELWLMGCFLTSDSCKDIAAVLICNGKLKTLKLGHNEIGDTGVRQLCAALQHPHCKLECLGLQTCPITRACCDDIAAALIACKTLRSLNLDWIALDADAVVVLCEALSHPDCALQMLGLHKSGFDEETQKILMSVEEKIPHLTISHGPWIDEEYKIRGVLL", "length": 991 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W24-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "NLRP14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSSSSSFFPDFGLLLYLEELNKEELNTFKLFLKETMEPEHGLTPWNEVKKARREDLANLMKKYYPGEKAWSVSLKIFGKMNLKDLCERAKEEINWSAQTIGPDDAKAGETQEDQEAVLGDGTEYRNRIKEKFCITWDKKSLAGKPEDFHHGIAEKDRKLLEHLFDVDVKTGAQPQIVVLQGAAGVGKTTLVRKAMLDWAEGSLYQQRFKYVFYLNGREINQLKERSFAQLISKDWPSTEGPIEEIMYQPSSLLFIIDSFDELNFAFEEPEFALCEDWTQEHPVSFLMSSLLRKVMLPEASLLVTTRLTTSKRLKQLLKNHHYVELLGMSEDAREEYIYQFFEDKRWAMKVFSSLKSNEMLFSMCQVPLVCWAACTCLKQQMEKGGDVTLTCQTTTALFTCYISSLFTPVDGGSPSLPNQAQLRRLCQVAAKGIWTMTYVFYRENLRRLGLTQSDVSSFMDSNIIQKDAEYENCYVFTHLHVQEFFAAMFYMLKGSWEAGNPSCQPFEDLKSLLQSTSYKDPHLTQMKCFLFGLLNEDRVKQLERTFNCKMSLKIKSKLLQCMEVLGNSDYSPSQLGFLELFHCLYETQDKAFISQAMRCFPKVAINICEKIHLLVSSFCLKHCRCLRTIRLSVTVVFEKKILKTSLPTNTWDGDRITHCWQDLCSVLHTNEHLRELDLYHSNLDKSAMNILHHELRHPNCKLQKLLLKFITFPDGCQDISTSLIHNKNLMHLDLKGSDIGDNGVKSLCEALKHPECKLQTLRLESCNLTVFCCLNISNALIRSQSLIFLNLSTNNLLDDGVQLLCEALRHPKCYLERLSLESCGLTEAGCEYLSLALISNKRLTHLCLADNVLGDGGVKLMSDALQHAQCTLKSLVLRRCHFTSLSSEYLSTSLLHNKSLTHLDLGSNWLQDNGVKLLCDVFRHPSCNLQDLELMGCVLTNACCLDLASVILNNPNLRSLDLGNNDLQDDGVKILCDALRYPNCNIQRLGLEYCGLTSLCCQDLSSALICNKRLIKMNLTQNTLGYEGIVKLYKVLKSPKCKLQVLGLCKEAFDEEAQKLLEAVGVSNPHLIIKPDCNYHNEEDVSWWWCF", "length": 1093 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W25-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 13", "gene_name": "NLRP13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFSVITCPNGGTNQGLLPYLMALDQYQLEEFKLCLEPQQLMDFWSAPQGHFPRIPWANLRAADPLNLSFLLDEHFPKGQAWKVVLGIFQTMNLTSLCEKVRAEMKENVQTQELQDPTQEDLEMLEAAAGNMQTQGCQDPNQEELDELEEETGNVQAQGCQDPNQEEPEMLEEADHRRKYRENMKAELLETWDNISWPKDHVYIRNTSKDEHEELQRLLDPNRTRAQAQTIVLVGRAGVGKTTLAMQAMLHWANGVLFQQRFSYVFYLSCHKIRYMKETTFAELISLDWPDFDAPIEEFMSQPEKLLFIIDGFEEIIISESRSESLDDGSPCTDWYQELPVTKILHSLLKKELVPLATLLITIKTWFVRDLKASLVNPCFVQITGFTGDDLRVYFMRHFDDSSEVEKILQQLRKNETLFHSCSAPMVCWTVCSCLKQPKVRYYDLQSITQTTTSLYAYFFSNLFSTAEVDLADDSWPGQWRALCSLAIEGLWSMNFTFNKEDTEIEGLEVPFIDSLYEFNILQKINDCGGCTTFTHLSFQEFFAAMSFVLEEPREFPPHSTKPQEMKMLLQHVLLDKEAYWTPVVLFFFGLLNKNIARELEDTLHCKISPRVMEELLKWGEELGKAESASLQFHILRLFHCLHESQEEDFTKKMLGRIFEVDLNILEDEELQASSFCLKHCKRLNKLRLSVSSHILERDLEILETSKFDSRMHAWNSICSTLVTNENLHELDLSNSKLHASSVKGLCLALKNPRCKVQKLTCKSVTPEWVLQDLIIALQGNSKLTHLNFSSNKLGMTVPLILKALRHSACNLKYLCLEKCNLSAASCQDLALFLTSIQHVTRLCLGFNRLQDDGIKLLCAALTHPKCALERLELWFCQLAAPACKHLSDALLQNRSLTHLNLSKNSLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTREGCGELANALSHNHNVKILDLGENDLQDDGVKLLCEALKPHRALHTLGLAKCNLTTACCQHLFSVLSSSKSLVNLNLLGNELDTDGVKMLCKALKKSTCRLQKLG", "length": 1043 }, "evidence": [ { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BU40-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4A", "gene_name": "Nlrp4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEVLQLGLKQVSWTEVKKASRQDLASLLLKHYEEKPAWDMTFRFFQKINRKDLIERAKREIDGCPKLYRAHMKTKMTHDSSRAFTISIQNFLKEKFTEDDYDCFENLFQSKGTESKPQVVFLSGGAGVGKTLMLKRLMLAWIESPVFLHKFSYIFYFCCREVKQLKTASLAELISREWPGPSAPIEEILSKPEKLLFIIDSLEGMECDLFKWESELCDNCTEKQPVNVLLSSLLRRKMLPESSLLISATPESFEKMENRIEYTHVKIIKGLKERNIKMSFHRLFQDRNRAHEAFSLVRENEQLFTVCQVPVLCWMVATCLKEEIEKGRDPVSICRCTTSLYTTHIFNLFIPQNAHSPSKKSQDQLQGLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPILLDIGMLINIRESEKSYIFLHPSVQEVCAAIFYLLKSHVDHPSQEVKSIEKLMFAFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQIDGMKLFYCLFEMDDDTFLVEAMNCMEQINFVAKDYSDVIVAAHCLKHCFTLKKLSFSTQNVLSGAQEHSYMERLLTAWNHICSVFIISKDIQELRMKDTNLSESAFSVLYNNLKYHNYTLNVLVANNVFFVCEKYLFFELIQNCNLQHLNLSLTILSHSDVKLLCDVLSQAECNIEELVVAACSISSDDCKVFASVLISNKTLKHLNLASNTLDKGIASLCKSLCHPDCILEHLVLANCSLNEKCWDYLSEVLRRNKTLSHLDISSNDLKDEGLKVLCRALTLPDSVLKSLSLRHCLITISGCQDLAEVLRNNQNLVSLQVSNNKLEDTGVKLLCDAIKHPNCHLEDLGLEACELTGACCEDLASTFTQCKTLWAMNLLKNALDYNGLVVLCEALKQQTCATYVLGLQITDFDTETQAFLVAEQEKNPCLRILSSL", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C6J9-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4B", "gene_name": "Nlrp4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLFSDFGFIWYWKELNKIEFMYFKELLIHEILQMGLKQISWTEVKEASREDLAILLVKHCDGNQAWDTTFRVFQMIGRNVITNRATGEIAAHSTIYRAHLKEKLTHDCSRKFNISIQNFFQDEYDHLENLLVPNGTENNPKMVVLQGVAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCHDVKQLQTASLADLISREWPSPSAPMEEILSQPEKLLFIIDSLEGMEWNVTQQDSQLCYNCMEKQPVNVLLSSLLRKKILPESSLLISTSCETFKDLKDWIEYTNVRTITGFKENNINMCFHSLFQDRNIAQEAFSLIRENEQLFTVCQAPVVCYMVATCLKNEIESGKDPVSICRRTTSLYTTHILNLFIPHNAQNPSNNSEDLLDNLCFLAVEGMWTDISVFNEEALRRNGIMDSDIPTLLDIGILEQSRESENSYIFLHPSVQEFCAAMFYLLHSEMDHSCQGVYFIETFLFTFLNKIKKQWVFLGCFFFGLLHETEQEKLEAFFGYHLSKELRRQLFLWLELLLDTLHPDVKKINTMKFFYCLFEMEEEVFVQSAMNCREQIDVVVKGYSDFIVAAYCLSHGSALTDFSISAQNVLNEELGQRGKLLILWHQICSVFLRNKDIKTLRIEDTIFNEPVFKIFYSYLKNSSCILKTLVAYNVSFLCDKRLFLELIQSYNLEELYLRGTFLSHSDVEMLCDILNQAECNIRILDLANCSLCEHSWDYLSDVLRQNKSLRYLNISYNNLKDEGLKALCRALTLPNSALHSLSLEACQLTGACCKDLASTFTRYKCLRRINLAKNSLGFSGLFVLCKAMKDQTCTLYELKLRMADFDSDSQEFLLSEMERNKILSIENGV", "length": 863 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4B8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWNDTCTSHSSMVCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIGRTKMRDSPMSSLKLELLFEPEDGHSEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSDYLQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFFHNSPKEEEEERRGGRPLDQVQCVFPDTHVACSSRLVNCCLTSSFCRGLFSSLSTNRSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSSSQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTNQNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHNHSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNRETKRALEALQEEKPELTIVFEISW", "length": 1033 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96MN2-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4", "gene_name": "NLRP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQMTLQLELKQIPWTEVKKASREELANLLIKHYEEQQAWNITLRIFQKMDRKDLCMKVMRERTGYTKTYQAHAKQKFSRLWSSKSVTEIHLYFEEEVKQEECDHLDRLFAPKEAGKQPRTVIIQGPQGIGKTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELRELPPTSLADLISREWPDPAAPITEIVSQPERLLFVIDSFEELQGGLNEPDSDLCGDLMEKRPVQVLLSSLLRKKMLPEASLLIAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQLFSICQIPLLCWILCTSLKQEMQKGKDLALTCQSTTSVYSSFVFNLFTPEGAEGPTPQTQHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGERESSYVFLHVCIQEFCAALFYLLKSHLDHPHPAVRCVQELLVANFEKARRAHWIFLGCFLTGLLNKKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFVKQAVNLLQEANFHIIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFKKEDEHSSTSDYSLICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFSGQSVLLFEVLFYQPDLKYLSFTLTKLSRDDIRSLCDALNYPAGNVKELALVNCHLSPIDCEVLAGLLTNNKKLTYLNVSCNQLDTGVPLLCEALCSPDTVLVYLMLAFCHLSEQCCEYISEMLLRNKSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDLASALISNQNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLASVLTCSKTLQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRKTDFDEETQALLTAEEERNPNLTITDDCDTITRVEI", "length": 994 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW", "length": 1036 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9NX02-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 2", "gene_name": "NLRP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"length": 1062 }, "evidence": [ { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-227#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5L8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5L8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5L8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5L8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 797, "end_pos": 799, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" }, { "start_pos": 929, "end_pos": 931, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z5L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5L8" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 803, "end_pos": 995, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z5L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5L8" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 125, "end_pos": 259, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 693, "end_pos": 695 }, { "start_pos": 797, "end_pos": 799 }, { "start_pos": 7, "end_pos": 9 }, { "start_pos": 929, "end_pos": 931 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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{ "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M6Z5Q0-1", "uniprot_ac": "A0A8M6Z5Q0", "uniprot_id": "A0A8M6Z5Q0_DANRE", "mass": { "chemical_mass": 45736.0, "monoisotopic_mass": 45736.0 }, "refseq": { "ac": "XP_017210937", "name": "scavenger receptor cysteine-rich domain-containing group B protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210937" }, "gene_names": [ { "name": "LOC108183587", "type": "recommended", "evidence": [ { "id": "A0A8M6Z5Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5Q0" } ] }, { "name": "LOC108183587", "type": "synonym", "evidence": [ { "id": "XP_017210937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210937" } ] } ], "protein_names": [ { "name": "Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D", "type": "recommended", "evidence": [ { "id": "A0A8M6Z5Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5Q0/entry#names_and_taxonomy" } ] }, { "name": "scavenger receptor cysteine-rich domain-containing group B protein", "type": "synonym", "evidence": [ { "id": "XP_017210937", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210937" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017210937.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017210937", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210937" } ] }, { "annotation": "Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5Q0#function" }, { "database": "UniProtKB", "id": "ARBA00058074", "url": "https://www.uniprot.org/uniprotkb/ARBA00058074#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5Q0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108183587", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5Q0", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z5Q0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z5Q0", "database": "AlphaFoldDB", "categories": [] }, { "id": "108183587", "url": "https://www.ncbi.nlm.nih.gov/gene/108183587", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036772", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036772", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108183587", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108183587", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z5Q0", "url": "https://www.orthodb.org/?gene=A0A8M6Z5Q0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48071", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48071", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48071:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48071:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017210937", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210937", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5Q0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z5Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5Q0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNRVNCVGNESSLADCAMESLGPIGCLNDLCAGVICQPRTRLVSGINSCSGRVEVFHNGLWGTVCDDYWGLTNAAVVCRELGCGDVIEAKSNAYFAEGSGQILMDDVNCSRDDNALSKCEFAGWGVHNCVHSEDAGVVCQAKMWLFNNFDSCSGTVAVFHNASWGAVCADDDWDLPDATVVCREIGCWKSVSVFTDYSWSSTPLRTWMNNVSCSGDETALSTCAFQGWGPDNCDPKYAGVICRLPVRLTGGRDACSGLVEVFHDGQWGTVNADGWDLADAAVVCREMGCGDAVQATGGAFGRGIGPIWMTLVDCVGSESSLIQCSLDRWLPNHVNHLNDAGVVCTHSSSFSISSTQDSSVKVLLRIKVKTDARFNPNNPKTLSKITEMQKKLQISGSFSLTWKTQEGGKVFKEVALKKNVEVTCN", "length": 425, "header": "tr|A0A8M6Z5Q0-1|A0A8M6Z5Q0_DANRE Isoform 1 of Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D OS=Danio rerio OX=7955 GN=LOC108183587 PE=4 SV=2 CANONICAL=A0A8M6Z5Q0-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z5Q0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5Q0/entry#A0A8M6Z5Q0-1", "sequence": { "sequence": "MNRVNCVGNESSLADCAMESLGPIGCLNDLCAGVICQPRTRLVSGINSCSGRVEVFHNGLWGTVCDDYWGLTNAAVVCRELGCGDVIEAKSNAYFAEGSGQILMDDVNCSRDDNALSKCEFAGWGVHNCVHSEDAGVVCQAKMWLFNNFDSCSGTVAVFHNASWGAVCADDDWDLPDATVVCREIGCWKSVSVFTDYSWSSTPLRTWMNNVSCSGDETALSTCAFQGWGPDNCDPKYAGVICRLPVRLTGGRDACSGLVEVFHDGQWGTVNADGWDLADAAVVCREMGCGDAVQATGGAFGRGIGPIWMTLVDCVGSESSLIQCSLDRWLPNHVNHLNDAGVVCTHSSSFSISSTQDSSVKVLLRIKVKTDARFNPNNPKTLSKITEMQKKLQISGSFSLTWKTQEGGKVFKEVALKKNVEVTCN", "length": 425, "header": "tr|A0A8M6Z5Q0-1|A0A8M6Z5Q0_DANRE Isoform 1 of Soluble scavenger receptor cysteine-rich domain-containing protein SSC5D OS=Danio rerio OX=7955 GN=LOC108183587 PE=4 SV=2 CANONICAL=A0A8M6Z5Q0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108183587", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108183587", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5Q0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5Q0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z5Q0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5Q0" }, { "id": "PS50287", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50287" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SRCR", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 37, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 210, "end_pos": 212 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z5T1-1", "uniprot_ac": "A0A8M6Z5T1", "uniprot_id": "A0A8M6Z5T1_DANRE", "mass": { "chemical_mass": 224992.0, "monoisotopic_mass": 224992.0 }, "refseq": {}, "gene_names": [ { "name": "zgc:113265", "type": "recommended", "evidence": [ { "id": "A0A8M6Z5T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1" } ] }, { "name": "zgc:113265", "type": "synonym", "evidence": [ { "id": "A0A8M6Z5T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1" } ] } ], "protein_names": [ { "name": "Uncharacterized protein zgc:113265 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M6Z5T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0AC58J4B3", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4B3#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5T1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050327-21", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-21", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd01644", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01644", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "541498", "url": "https://www.ncbi.nlm.nih.gov/gene/541498", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050636", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050636", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:541498", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:541498", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z5T1", "url": "https://www.orthodb.org/?gene=A0A8M6Z5T1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47331:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47331:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47772:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47772:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03564", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03564", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_068075555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075555", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z5T1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z5T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4A8", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4A8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4B3", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4B3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050327-21", "url": "https://zfin.org/ZDB-GENE-050327-21", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMTDHGSNLCTPAKVNEQIDNVQNKEVDEEVEAQSEELDTNVRRSTRERTQTDRMLAYQREESHKAERKLMHAYEKWKAEARKARSQLKLDISESELATLIDSLEKEKDSVMNAYIKVRSNVTPPTDMRRKIDACDAVTKDIVKIAYERISGVDGGFDNETVKGHLRELLERDYARSVYGSTVSRISSKSSTPISQPSLNSILMAKRIEAAAELAAKEAEYATVIEEREQREKLRLLEEKQRKELEAQKGEFERLQAMKEVRAARARLEVYDKEETVDTVNQDEGLQQPVSPPTHKPVYLSSVNPTPNISLQRPNADVSQLAQAVQDSITLNRLPMPEPTVFSGDPIHFIEWKASFQSLIDKRHISSGDKLYYLKKYVTGPALKVLDGIFYRNDEEAYKDAWKRLLDRYGQPFIIQRAFREKLACWPKIQSKDSVGLRNFSDFLNSCKDAMPHVKGLEILNDCEENRKLVSKLPDWAAARWNRQTTQTLSETQDFPTFQEFAHFMSVEAEVACNPVTSFHALHVLEPNKEKNYFKVSKPKANVFHTKTVTQHDNSKPTGKVNKPCLFCQNGEHQIHECSKFSARSLEERRQFVKNTRLCYGCLRLGHSAKDCRSRHCCNTCKGRHPTCLHDDSFNRKVRSSSAQSPENVHEGVATMSLSVESGCTPVNTSMIVPVWLSTHKDPVSEKLIYALLDTQSDSVFIECAVCKSLKVDSCPVTLKLTTLVGKDSLMSSERISGLRVRGFNSSLIIDLPPAYTKECIPVDRAHIPIMETASHWKHLATLADKIPPLQNCEVGLLIGYNCSRALAPREVILGTENEPYAVRTDLGWSIIGPSLTHFEPQSSAAMCHRVSIKEIPAVTPTDVIKVLESDFKDTEGHTKVTSQEDIMFLRKLEENIRLNKDSHLEMPLPFRKRPYLPDNKPLAVIRLQHLKRRLMRDQEYREHYVTFMEEVIEKGNAEQVFEEGREGERWYIPHHGVYHSKKPGKLRIVFDCSARYKGTSLNDHLLTGPDLMNSLTGILLRFRQYPVALMCDVEKMFHQFHVDHADRDYLRFLWWRNGDFNSQPQTFRMTVHLFGASSSPGCANYGLKHLAREGERLYPLGSQFIMQDFYMDDGVSSIESTEKAIKLAEEARQLCALGSLSLHKFVSNDKEVLKTIPPSECAVDVTAVDLALTDQPLERALGIYWSLEQDNFKFHITVKDQPATRRGILSIVASLFDPLGFLAPFVLKGKTILQEMCRSGMGWDDNLPADLQSAWEHWKADLVNLEKIEVPRCIMPSGFGRIIRREIHHFSDASMSGYGQCSYLRLENEQGDISCSLLMAKSRVAPLKITTIPRLELAAAVVSVAVNDMLKEEMNLADAEAFFWTDSQVVLGYINNEARRFHTFVANRVQRIHRTTTPQQWRYICSDENPADYVSRGLSVNNLVTSNWFRGPKVLWEKQIPAPMEISKQLPIGDPEVKKVQSLNTQTVQYSCLSDRLTKLSSWSKAIQAVARLIRRVRKDKSHNHSTLAERNDALCIIIKDLQKQTYAEEITLLCKGKQLPRSNRLYNLDTFVDQDGLLKVGGRLCEASIPNAVKYPVILPKEHQLTKLLIADCHDKMAHQGKGMTINEIRSRGFWITGVNRTVASFVRQCVRCRKLRGPTEEQKMANLPSERIEPSPPFTYSGMDVFGPFITSKGRKSNKRYGLLFTCFCCRAIHIEMLDDMSTDAFINGLRCFIAIRGAVHQIRCDQGSNFIGARNELTKAMEEIDTNRLVTFLAEKQCDFVFNAPHSSHTGGVWERQIRTVRSVLRSTLSQSSGRLDDSSLRAFFYEAMSIVNSRPLTVDSLTDPSSPEPLTPNHLLTLKPTQALPPPGKFVREDVYARKRWRHVQYLAEQFWGRWHKEYVSNITTRQCWHTPRRNMQVGDIVLEKAVDLPRNEWRLARIIEAVTDKDGLVRRVKIQFGDRNLGKDGKRLHKPSVVERPVQKLVLLMEAA", "length": 1974, "header": "tr|A0A8M6Z5T1-1|A0A8M6Z5T1_DANRE Isoform 1 of Uncharacterized protein zgc:113265 isoform X1 OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A0A8M6Z5T1-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z5T1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1/entry#A0A8M6Z5T1-1", "sequence": { "sequence": "MMTDHGSNLCTPAKVNEQIDNVQNKEVDEEVEAQSEELDTNVRRSTRERTQTDRMLAYQREESHKAERKLMHAYEKWKAEARKARSQLKLDISESELATLIDSLEKEKDSVMNAYIKVRSNVTPPTDMRRKIDACDAVTKDIVKIAYERISGVDGGFDNETVKGHLRELLERDYARSVYGSTVSRISSKSSTPISQPSLNSILMAKRIEAAAELAAKEAEYATVIEEREQREKLRLLEEKQRKELEAQKGEFERLQAMKEVRAARARLEVYDKEETVDTVNQDEGLQQPVSPPTHKPVYLSSVNPTPNISLQRPNADVSQLAQAVQDSITLNRLPMPEPTVFSGDPIHFIEWKASFQSLIDKRHISSGDKLYYLKKYVTGPALKVLDGIFYRNDEEAYKDAWKRLLDRYGQPFIIQRAFREKLACWPKIQSKDSVGLRNFSDFLNSCKDAMPHVKGLEILNDCEENRKLVSKLPDWAAARWNRQTTQTLSETQDFPTFQEFAHFMSVEAEVACNPVTSFHALHVLEPNKEKNYFKVSKPKANVFHTKTVTQHDNSKPTGKVNKPCLFCQNGEHQIHECSKFSARSLEERRQFVKNTRLCYGCLRLGHSAKDCRSRHCCNTCKGRHPTCLHDDSFNRKVRSSSAQSPENVHEGVATMSLSVESGCTPVNTSMIVPVWLSTHKDPVSEKLIYALLDTQSDSVFIECAVCKSLKVDSCPVTLKLTTLVGKDSLMSSERISGLRVRGFNSSLIIDLPPAYTKECIPVDRAHIPIMETASHWKHLATLADKIPPLQNCEVGLLIGYNCSRALAPREVILGTENEPYAVRTDLGWSIIGPSLTHFEPQSSAAMCHRVSIKEIPAVTPTDVIKVLESDFKDTEGHTKVTSQEDIMFLRKLEENIRLNKDSHLEMPLPFRKRPYLPDNKPLAVIRLQHLKRRLMRDQEYREHYVTFMEEVIEKGNAEQVFEEGREGERWYIPHHGVYHSKKPGKLRIVFDCSARYKGTSLNDHLLTGPDLMNSLTGILLRFRQYPVALMCDVEKMFHQFHVDHADRDYLRFLWWRNGDFNSQPQTFRMTVHLFGASSSPGCANYGLKHLAREGERLYPLGSQFIMQDFYMDDGVSSIESTEKAIKLAEEARQLCALGSLSLHKFVSNDKEVLKTIPPSECAVDVTAVDLALTDQPLERALGIYWSLEQDNFKFHITVKDQPATRRGILSIVASLFDPLGFLAPFVLKGKTILQEMCRSGMGWDDNLPADLQSAWEHWKADLVNLEKIEVPRCIMPSGFGRIIRREIHHFSDASMSGYGQCSYLRLENEQGDISCSLLMAKSRVAPLKITTIPRLELAAAVVSVAVNDMLKEEMNLADAEAFFWTDSQVVLGYINNEARRFHTFVANRVQRIHRTTTPQQWRYICSDENPADYVSRGLSVNNLVTSNWFRGPKVLWEKQIPAPMEISKQLPIGDPEVKKVQSLNTQTVQYSCLSDRLTKLSSWSKAIQAVARLIRRVRKDKSHNHSTLAERNDALCIIIKDLQKQTYAEEITLLCKGKQLPRSNRLYNLDTFVDQDGLLKVGGRLCEASIPNAVKYPVILPKEHQLTKLLIADCHDKMAHQGKGMTINEIRSRGFWITGVNRTVASFVRQCVRCRKLRGPTEEQKMANLPSERIEPSPPFTYSGMDVFGPFITSKGRKSNKRYGLLFTCFCCRAIHIEMLDDMSTDAFINGLRCFIAIRGAVHQIRCDQGSNFIGARNELTKAMEEIDTNRLVTFLAEKQCDFVFNAPHSSHTGGVWERQIRTVRSVLRSTLSQSSGRLDDSSLRAFFYEAMSIVNSRPLTVDSLTDPSSPEPLTPNHLLTLKPTQALPPPGKFVREDVYARKRWRHVQYLAEQFWGRWHKEYVSNITTRQCWHTPRRNMQVGDIVLEKAVDLPRNEWRLARIIEAVTDKDGLVRRVKIQFGDRNLGKDGKRLHKPSVVERPVQKLVLLMEAA", "length": 1974, "header": "tr|A0A8M6Z5T1-1|A0A8M6Z5T1_DANRE Isoform 1 of Uncharacterized protein zgc:113265 isoform X1 OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A0A8M6Z5T1-1" }, "locus": {} }, { "isoform_ac": "A0AC58J4A8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1/entry#A0AC58J4A8-1", "sequence": { "sequence": "MPHVKGLEILNDCEENRKLVSKLPDWAAARWNRQTTQTLSETQDFPTFQEFAHFMSVEAEVACNPVTSFHALHVLEPNKEKNYFKVSKPKANVFHTKTVTQHDNSKPTGKVNKPCLFCQNGEHQIHECSKFSARSLEERRQFVKNTRLCYGCLRLGHSAKDCRSRHCCNTCKGRHPTCLHDDSFNRKVRSSSAQSPENVHEGVATMSLSVESGCTPVNTSMIVPVWLSTHKDPVSEKLIYALLDTQSDSVFIECAVCKSLKVDSCPVTLKLTTLVGKDSLMSSERISGLRVRGFNSSLIIDLPPAYTKECIPVDRAHIPIMETASHWKHLATLADKIPPLQNCEVGLLIGYNCSRALAPREVILGTENEPYAVRTDLGWSIIGPSLTHFEPQSSAAMCHRVSIKEIPAVTPTDVIKVLESDFKDTEGHTKVTSQEDIMFLRKLEENIRLNKDSHLEMPLPFRKRPYLPDNKPLAVIRLQHLKRRLMRDQEYREHYVTFMEEVIEKGNAEQVFEEGREGERWYIPHHGVYHSKKPGKLRIVFDCSARYKGTSLNDHLLTGPDLMNSLTGILLRFRQYPVALMCDVEKMFHQFHVDHADRDYLRFLWWRNGDFNSQPQTFRMTVHLFGASSSPGCANYGLKHLAREGERLYPLGSQFIMQDFYMDDGVSSIESTEKAIKLAEEARQLCALGSLSLHKFVSNDKEVLKTIPPSECAVDVTAVDLALTDQPLERALGIYWSLEQDNFKFHITVKDQPATRRGILSIVASLFDPLGFLAPFVLKGKTILQEMCRSGMGWDDNLPADLQSAWEHWKADLVNLEKIEVPRCIMPSGFGRIIRREIHHFSDASMSGYGQCSYLRLENEQGDISCSLLMAKSRVAPLKITTIPRLELAAAVVSVAVNDMLKEEMNLADAEAFFWTDSQVVLGYINNEARRFHTFVANRVQRIHRTTTPQQWRYICSDENPADYVSRGLSVNNLVTSNWFRGPKVLWEKQIPAPMEISKQLPIGDPEVKKVQSLNTQTVQYSCLSDRLTKLSSWSKAIQAVARLIRRVRKDKSHNHSTLAERNDALCIIIKDLQKQTYAEEITLLCKGKQLPRSNRLYNLDTFVDQDGLLKVGGRLCEASIPNAVKYPVILPKEHQLTKLLIADCHDKMAHQGKGMTINEIRSRGFWITGVNRTVASFVRQCVRCRKLRGPTEEQKMANLPSERIEPSPPFTYSGMDVFGPFITSKGRKSNKRYGLLFTCFCCRAIHIEMLDDMSTDAFINGLRCFIAIRGAVHQIRCDQGSNFIGARNELTKAMEEIDTNRLVTFLAEKQCDFVFNAPHSSHTGGVWERQIRTVRSVLRSTLSQSSGRLDDSSLRAFFYEAMSIVNSRPLTVDSLTDPSSPEPLTPNHLLTLKPTQALPPPGKFVREDVYARKRWRHVQYLAEQFWGRWHKEYVSNITTRQCWHTPRRNMQVGDIVLEKAVDLPRNEWRLARIIEAVTDKDGLVRRVKIQFGDRNLGKDGKRLHKPSVVERPVQKLVLLMEAA", "length": 1524, "header": "tr|A0AC58J4A8-1|A0AC58J4A8_DANRE Computationally mapped isoform of Uncharacterized protein zgc:113265 isoform X2 OS=Danio rerio OX=7955 GN=zgc:113265 PE=4 SV=1 CANONICAL=A0A8M6Z5T1-1" }, "locus": {} }, { "isoform_ac": "A0AC58J4B3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1/entry#A0AC58J4B3-1", "sequence": { "sequence": "MHPVCSYGVVQSLRTANATIKAQRRTVQHQCMSLILLFLQPGCYSKSFSHLSSHNKHMLMHTGERPFTCTQCGKSFRQSSHLTKHMLIHTGEKPFPCTQCGKSFRQSSSLNKHMLIHTGEKPFTCTQCGKSFTQSSNLYQHMMIHTGEKPLSCTQCGKSFSQSSSLNQHMLTHTGERPFTCTQCGKSFTQSSSLNLHMKIHTGEKPHTCTQCGKSFTISSFLNQHMLIHTGERPHKCDQCGKTFATGSFLKLHLRVHTTEKPYSCSVCGRSFTWRTNLNRHQKIHTGVREHYCFECGKTFVTTGDLERHQRIHTGEKPYTCSHCDKRFRQLGSLKRHEKIHTGEKPYTCTQCGKSFTRSSHLNIHMLVHTGEKPFTCTQCGKSFRHTSNLNKHMMIHTGERPFTCTQCGKSFTRSSNLNEHMLIHTGKKPFTCTQCGRDFRQAAHLNQHMLIHTGEKPHRCDHCGQTFARSSFLNRHVRVHTNEKQSSCSVCGKSFTRQSSLRKHQKIHTGVREHVCFECGKTFITADELRRHQRIHTGEKPYTCSHCDKRFSQSGSLKAHERTHSVIC", "length": 569, "header": "tr|A0AC58J4B3-1|A0AC58J4B3_DANRE Computationally mapped isoform of Uncharacterized protein zgc:113265 isoform X3 OS=Danio rerio OX=7955 GN=zgc:113265 PE=3 SV=1 CANONICAL=A0A8M6Z5T1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 123, "start_aa": "Thr", "end_pos": 123, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr123", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 860, "start_aa": "Thr", "end_pos": 860, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr860", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:541498", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:541498", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5T1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5T1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z5T1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1505, "end_pos": 1507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1622, "end_pos": 1624, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1887, "end_pos": 1889, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 745, "end_pos": 747, "annotation": "n_glycosylation_sequon" }, { "start_pos": 802, "end_pos": 804, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z5T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1" }, { "id": "PS50158", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC-type", "eco_id": "ECO_0000259", "start_pos": 599, "end_pos": 614, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z5T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z5T1" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 1656, "end_pos": 1845, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 123, 860 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 1505, "end_pos": 1507 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 1622, "end_pos": 1624 }, { "start_pos": 1887, "end_pos": 1889 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 668, "end_pos": 670 }, { "start_pos": 745, "end_pos": 747 }, { "start_pos": 802, "end_pos": 804 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z624-1", "uniprot_ac": "A0A8M6Z624", "uniprot_id": "A0A8M6Z624_DANRE", "mass": { "chemical_mass": 56163.0, "monoisotopic_mass": 56163.0 }, "refseq": { "ac": "XP_017210650", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210650" }, "gene_names": [ { "name": "LOC108183307", "type": "recommended", "evidence": [ { "id": "A0A8M6Z624", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z624" } ] }, { "name": "LOC108183307", "type": "synonym", "evidence": [ { "id": "XP_017210650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210650" } ] } ], "protein_names": [ { "name": "Tyr recombinase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M6Z624", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z624/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017210650", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210650" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017210650.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017210650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210650" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z624", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z624" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108183307", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z624", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z624", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z624", "database": "AlphaFoldDB", "categories": [] }, { "id": "108183307", "url": "https://www.ncbi.nlm.nih.gov/gene/108183307", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013762", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013762", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108183307", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108183307", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z624", "url": "https://www.orthodb.org/?gene=A0A8M6Z624", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35617", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35617", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35617:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35617:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_017210650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210650", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z624", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z624", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z624-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z624-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEQATFSVVTGNPCPRRSEQGCRPFVKGEPTLRGVASPSSNSGPALEEIRPGRRRSLRLARKRPLSYVLLATGRGCPPRRGRTGSSMAQCAALCVPSSLPNNPNPIQGEGTRLETDPDSTEVAQGSMAGRDNPSSACTAMAPPITYGPPVPSEWGNLPPSSRQGGSLGLARERANLNTLGLSPRVIATIQNARASSTRSLYDCKWRVFEEWCEERRLISYQCSVADILGFLQGLMDCGKSFSTIKVYLAAITACHVGFDGSTAGQHPLIRRFMKGARRSLPVTRRVVPEWDLSMVLDALTHHPFETLEAISLKHLSFKTALLLALASAKRVSDLLALSVHPSCIKFSLSGEKVSLRPNPAFMPKCFPNFSCEGVELSAFHPPPFSSTEDQRLNALCPVRALRAYINRTSSFRRSDQLFISWAPPNRGNPISKQRLSHWLVEAISLAYESKGVRPPGGLRAHSTRGMAASWALFRGVSLQDICAAASWASPHTFVRYYRLDVTQTPVAHSVLGVGSS", "length": 516, "header": "tr|A0A8M6Z624-1|A0A8M6Z624_DANRE Isoform 1 of Tyr recombinase domain-containing protein OS=Danio rerio OX=7955 GN=LOC108183307 PE=4 SV=2 CANONICAL=A0A8M6Z624-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z624-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z624/entry#A0A8M6Z624-1", "sequence": { "sequence": "MEQATFSVVTGNPCPRRSEQGCRPFVKGEPTLRGVASPSSNSGPALEEIRPGRRRSLRLARKRPLSYVLLATGRGCPPRRGRTGSSMAQCAALCVPSSLPNNPNPIQGEGTRLETDPDSTEVAQGSMAGRDNPSSACTAMAPPITYGPPVPSEWGNLPPSSRQGGSLGLARERANLNTLGLSPRVIATIQNARASSTRSLYDCKWRVFEEWCEERRLISYQCSVADILGFLQGLMDCGKSFSTIKVYLAAITACHVGFDGSTAGQHPLIRRFMKGARRSLPVTRRVVPEWDLSMVLDALTHHPFETLEAISLKHLSFKTALLLALASAKRVSDLLALSVHPSCIKFSLSGEKVSLRPNPAFMPKCFPNFSCEGVELSAFHPPPFSSTEDQRLNALCPVRALRAYINRTSSFRRSDQLFISWAPPNRGNPISKQRLSHWLVEAISLAYESKGVRPPGGLRAHSTRGMAASWALFRGVSLQDICAAASWASPHTFVRYYRLDVTQTPVAHSVLGVGSS", "length": 516, "header": "tr|A0A8M6Z624-1|A0A8M6Z624_DANRE Isoform 1 of Tyr recombinase domain-containing protein OS=Danio rerio OX=7955 GN=LOC108183307 PE=4 SV=2 CANONICAL=A0A8M6Z624-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108183307", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108183307", "resource": "KEGG Pathway" } ], "orthologs": [], 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"start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z624", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z624" }, { "id": "PS51898", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51898" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyr recombinase", "eco_id": "ECO_0000259", "start_pos": 281, "end_pos": 509, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 368, "end_pos": 370 }, { "start_pos": 406, 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z642-1", "uniprot_ac": "A0A8M6Z642", "uniprot_id": "A0A8M6Z642_DANRE", "mass": { "chemical_mass": 35819.0, "monoisotopic_mass": 35819.0 }, "refseq": { "ac": "XP_017211343", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211343" }, "gene_names": [ { "name": "LOC108184065", "type": "recommended", "evidence": [ { "id": "A0A8M6Z642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z642" } ] }, { "name": "LOC108184065", "type": "synonym", "evidence": [ { "id": "XP_017211343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211343" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M6Z642", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z642/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017211343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211343" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017211343.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211343", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211343" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z642", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z642" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108184065", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z642", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z642", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z642", "database": "AlphaFoldDB", "categories": [] }, { "id": "108184065", "url": "https://www.ncbi.nlm.nih.gov/gene/108184065", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:108184065", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108184065", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z642", "url": "https://www.orthodb.org/?gene=A0A8M6Z642", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_017211343", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211343", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z642", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z642", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z642-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z642-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDGVAMMGVGATMDGVATMDVGATMDVVATMDVVATMDVVATMDVVATMDVVATMDVVATMDVVATMDVVATMDVVATMDVVATMDVVATMDGVATMDGVATMGGVAMMCVGATMDGVATMDGVATMGVGATMDGVATMGVGATMDGVAMMAVGATMDGVAMMGVGATMDGVAMMAVGATMDGVAMMGVGATMDGVAMMDGVAMMGIEAMMDGMGAEVMMGTVVMMDVGVMIKKVMMDTVVMMDAVVMMDVVVKMDAVVKMDGAVMMDAVLKMDSVLKMDSVLKMDAVLKMDAVLKMDLVLKVDAVLKAAQSDAVDSDKFADVPTLGFTFNKYFNANEVLGYFIFYKILS", "length": 350, "header": "tr|A0A8M6Z642-1|A0A8M6Z642_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108184065 PE=4 SV=3 CANONICAL=A0A8M6Z642-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z642-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z642/entry#A0A8M6Z642-1", "sequence": { "sequence": "MDGVAMMGVGATMDGVATMDVGATMDVVATMDVVATMDVVATMDVVATMDVVATMDVVATMDVVATMDVVATMDVVATMDVVATMDVVATMDGVATMDGVATMGGVAMMCVGATMDGVATMDGVATMGVGATMDGVATMGVGATMDGVAMMAVGATMDGVAMMGVGATMDGVAMMAVGATMDGVAMMGVGATMDGVAMMDGVAMMGIEAMMDGMGAEVMMGTVVMMDVGVMIKKVMMDTVVMMDAVVMMDVVVKMDAVVKMDGAVMMDAVLKMDSVLKMDSVLKMDAVLKMDAVLKMDLVLKVDAVLKAAQSDAVDSDKFADVPTLGFTFNKYFNANEVLGYFIFYKILS", "length": 350, "header": "tr|A0A8M6Z642-1|A0A8M6Z642_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108184065 PE=4 SV=3 CANONICAL=A0A8M6Z642-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108184065", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108184065", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z652-1", "uniprot_ac": "A0A8M6Z652", "uniprot_id": "A0A8M6Z652_DANRE", "mass": { "chemical_mass": 47518.0, "monoisotopic_mass": 47518.0 }, "refseq": { "ac": "XP_017211393", "name": "cell adhesion molecule CEACAM6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211393" }, "gene_names": [ { "name": "si:ch211-286b5.9", "type": "recommended", "evidence": [ { "id": "A0A8M6Z652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z652" } ] }, { "name": "si:ch211-286b5.9", "type": "synonym", "evidence": [ { "id": "XP_017211393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211393" } ] } ], "protein_names": [ { "name": "Cell adhesion molecule CEACAM6", "type": "synonym", "evidence": [ { "id": "A0A8M6Z652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z652/entry#names_and_taxonomy" } ] }, { "name": "cell adhesion molecule CEACAM6", "type": "synonym", "evidence": [ { "id": "XP_017211393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211393" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017211393.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211393", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211393" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z652", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z652" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-286b5.9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z652", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-121214-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-63", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z652", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z652", "database": "AlphaFoldDB", "categories": [] }, { "id": "100003869", "url": "https://www.ncbi.nlm.nih.gov/gene/100003869", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100003869", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003869", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z652", "url": "https://www.orthodb.org/?gene=A0A8M6Z652", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46013", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46013", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46013:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46013:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13895", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13895", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017211393", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211393", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z652", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z652", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z652-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z652-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-121214-63", "url": "https://zfin.org/ZDB-GENE-121214-63", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFCVFSLIFLLVIPGVCRQKWGVKYSKMAICALKSSTIHLSGSYTHPYGLTVTKIFWTVNPKIGESINLLDNSNYTGRVEYFDKDKFFFVKLSNVRQEDEGMYCLRIETKVEKERHLGYPGIELTVTELRVETPEEVVEGDSPVLICKSSCNLGSTNFSWYKNGESFSKWVGENQLILQSVSREDSGNYSCAVRDLKDLPSPALTLNVRYPPKSVSVSVSGSAVIVSGDSVTLSCSSDSNPPALNFSWFKENQSSAIGSGQSFSISSFNTNHSGRYYCEAHNKYGSLRSASVSLTAKDGQNTLLYAAAGFGAAFICICIIIVALKIIRRKTADAEVQGDLSKQENKSTAVMDQMNSCDPDTGHQNDVMYASVCQKRPKEHQTAGDEDDVQYASVHHVRNADKVTAEDESQYGSASNCRLDDSSVIYSSIGVS", "length": 432, "header": "tr|A0A8M6Z652-1|A0A8M6Z652_DANRE Isoform 1 of Cell adhesion molecule CEACAM6 OS=Danio rerio OX=7955 GN=si:ch211-286b5.9 PE=4 SV=3 CANONICAL=A0A8M6Z652-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z652-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z652/entry#A0A8M6Z652-1", "sequence": { "sequence": "MFCVFSLIFLLVIPGVCRQKWGVKYSKMAICALKSSTIHLSGSYTHPYGLTVTKIFWTVNPKIGESINLLDNSNYTGRVEYFDKDKFFFVKLSNVRQEDEGMYCLRIETKVEKERHLGYPGIELTVTELRVETPEEVVEGDSPVLICKSSCNLGSTNFSWYKNGESFSKWVGENQLILQSVSREDSGNYSCAVRDLKDLPSPALTLNVRYPPKSVSVSVSGSAVIVSGDSVTLSCSSDSNPPALNFSWFKENQSSAIGSGQSFSISSFNTNHSGRYYCEAHNKYGSLRSASVSLTAKDGQNTLLYAAAGFGAAFICICIIIVALKIIRRKTADAEVQGDLSKQENKSTAVMDQMNSCDPDTGHQNDVMYASVCQKRPKEHQTAGDEDDVQYASVHHVRNADKVTAEDESQYGSASNCRLDDSSVIYSSIGVS", "length": 432, "header": "tr|A0A8M6Z652-1|A0A8M6Z652_DANRE Isoform 1 of Cell adhesion molecule CEACAM6 OS=Danio rerio OX=7955 GN=si:ch211-286b5.9 PE=4 SV=3 CANONICAL=A0A8M6Z652-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100003869", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003869", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABZ3NNN5-1", "protein_name": "CEA cell adhesion molecule 6", "gene_name": "Ceacam6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPPSAHPPMCVPWQGLLLAASLLTIWNFPATATPTAESVPPAVLEGQSVLLLAHNLPDNLLAYHWYKGKRSIDKDLIIMYEIKSQETKQGKLYSGKETLYPNGSLMLQNVTLKQSGIYHLNIHSADNQKSVFVEVFVYPLLSKPTIRSNRTTAVEGRDTVELTCDPLFRKTTYLWHLNGKKLRVDDRIALSRDNATLTLLRVSRHFRGRYECEAKNPLGAFHSDPFTLDVFYGPDTPEIFPPHKYFEEGRSMWLSCQAVSHPKAHYSWNVNGEPWNARQELSIHQVSISNNGLYTCLVNNAATGRNNSKVKEVIIVEKLPKPHIQVKNETVLEHHFVDLTCISENTGVSIWWTFNNQKLKATDRMTFSWNNRRLTIDPVTKEDAGAYQCEVSNPLNTRLSDPVKLAVLYQPSKSPLLSPTIVASLVAEVLAGLAILGGLAYFVFFKKLDNPESHEGVHRQERKNWKRAKRKRRKSKK", "length": 478 }, "evidence": [ { "id": "HGNC:9522", "url": "https://alliancegenome.org/gene/HGNC:9522#orthology", "database": "AGR" }, { "id": "HGNC:9519", "url": "https://alliancegenome.org/gene/HGNC:9519#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P11465-1", "protein_name": "Pregnancy-specific beta-1-glycoprotein 2", "gene_name": "PSG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPLSAPPCTEHIKWKGLLVTASLLNFWNLPTTAQVTIEAQPPKVSEGKDVLLLVHNLPQNLTGYIWYKGQIRDLYHYITSYVVDGQIIIYGPAYSGRETAYSNASLLIQNVTREDAGSYTLHIIKRGDGTRGVTGYFTFTLYLETPKPSISSSNLNPREAMETVILTCDPETPDTSYQWWMNGQSLPMTHRFQLSETNRTLFLFGVTKYTAGPYECEIRNSGSASRSDPVTLNLLHGPDLPRIHPSYTNYRSGDNLYLSCFANSNPPAQYSWTINGKFQQSGQNLFIPQITTKHSGLYVCSVRNSATGEESSTSLTVKVSASTRIGLLPLLNPT", "length": 335 }, "evidence": [ { "id": "HGNC:9519", "url": "https://alliancegenome.org/gene/HGNC:9519#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121214-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-63#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q15238-1", "protein_name": "Pregnancy-specific beta-1-glycoprotein 5", "gene_name": "PSG5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPLSAPPCTQHITWKGLLLTASLLNFWNLPITAQVTIEALPPKVSEGKDVLLLVHNLPQNLAGYIWYKGQLMDLYHYITSYVVDGQINIYGPAYTGRETVYSNASLLIQNVTREDAGSYTLHIIKRGDRTRGVTGYFTFNLYLKLPKPYITINNSKPRENKDVLAFTCEPKSENYTYIWWLNGQSLPVSPRVKRPIENRILILPSVTRNETGPYECEIRDRDGGMRSDPVTLNVLYGPDLPSIYPSFTYYRSGENLYLSCFAESNPPAEYFWTINGKFQQSGQKLSIPQITTKHRGLYTCSVRNSATGKESSKSMTVEVSAPSGIGRLPLLNPI", "length": 335 }, "evidence": [ { "id": "HGNC:9522", "url": "https://alliancegenome.org/gene/HGNC:9522#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121214-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-63#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z652", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z652" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 120, "end_pos": 207, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 245, "end_pos": 247 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 271, "end_pos": 273 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z6A4-1", "uniprot_ac": "A0A8M6Z6A4", "uniprot_id": "A0A8M6Z6A4_DANRE", "mass": { "chemical_mass": 67851.0, "monoisotopic_mass": 67851.0 }, "refseq": { "ac": "XP_017210951", "name": "uncharacterized protein si:dkey-23a23.2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210951" }, "gene_names": [ { "name": "si:dkey-23a23.2", "type": "recommended", "evidence": [ { "id": "A0A8M6Z6A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6A4" } ] }, { "name": "si:dkey-23a23.2", "type": "synonym", "evidence": [ { "id": "XP_017210951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210951" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkey-23a23.2", "type": "synonym", "evidence": [ { "id": "A0A8M6Z6A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6A4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkey-23a23.2", "type": "synonym", "evidence": [ { "id": "XP_017210951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210951" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017210951.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017210951", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210951" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6A4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6A4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-23a23.2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6A4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-158", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-158", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z6A4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z6A4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100034534", "url": "https://www.ncbi.nlm.nih.gov/gene/100034534", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001214", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001214", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046341", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046341", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100034534", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100034534", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z6A4", "url": "https://www.orthodb.org/?gene=A0A8M6Z6A4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47306", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47306", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47306:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47306:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00856", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00856", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017210951", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210951", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6A4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-158", "url": "https://zfin.org/ZDB-GENE-060503-158", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASEMSVNRNIFYCLLCQKPQKTLSVHLTRLCMKASTPAERAKELERAKASNRAWMMTSRTWDYNQLCQILPDRSSRTNMVKELLQRGFFIKNQPTEPETDVVSQSTEPETAVVSQPTEPEKATMSAIPDSAAILRAAKPEFLRVCMKLQNNIEVLSSEKVLFRYYCEAILIHHYFQSPGAVQAFTDSEWVDRLHHGGRVVTGVHSQKAMFALTLQEEVWFQLYFVQIRPENIRPEKCCNQFFLNSSGEALSNVAQDMRRLHDMFKLPLGSSQFMRKTLRISAKNLPTHQRDAITLYLACSSGDPHQTHRRLQPQQVVDTAVLLDSLVGFSIEDESRAVAETSEEIEPVKDFSSFISSFPVSRGGQPPTKMQRLNAGFPDDRVFYDKWRTVQYNQRQEYLLSQFTQSKPTAVTVAKVIGQEGWKGNHPKPEEIVSLWKPALKVTIEKDEIIIKSVSQQSWSGLAIKDFGPVRGQGVVATKRFSKGDIVCDYHGKVISGTSGRQIMEDIRDKSGYLFFFKAGQRDFCIDARTFPCECHPDKVSFGRKINHSSKMANLKLVHCVMKINGKDTDVVLFKALQDIDVNTHLKFDHKFISF", "length": 596, "header": "tr|A0A8M6Z6A4-1|A0A8M6Z6A4_DANRE Isoform 1 of Uncharacterized protein si:dkey-23a23.2 OS=Danio rerio OX=7955 GN=si:dkey-23a23.2 PE=4 SV=1 CANONICAL=A0A8M6Z6A4-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z6A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6A4/entry#A0A8M6Z6A4-1", "sequence": { "sequence": "MASEMSVNRNIFYCLLCQKPQKTLSVHLTRLCMKASTPAERAKELERAKASNRAWMMTSRTWDYNQLCQILPDRSSRTNMVKELLQRGFFIKNQPTEPETDVVSQSTEPETAVVSQPTEPEKATMSAIPDSAAILRAAKPEFLRVCMKLQNNIEVLSSEKVLFRYYCEAILIHHYFQSPGAVQAFTDSEWVDRLHHGGRVVTGVHSQKAMFALTLQEEVWFQLYFVQIRPENIRPEKCCNQFFLNSSGEALSNVAQDMRRLHDMFKLPLGSSQFMRKTLRISAKNLPTHQRDAITLYLACSSGDPHQTHRRLQPQQVVDTAVLLDSLVGFSIEDESRAVAETSEEIEPVKDFSSFISSFPVSRGGQPPTKMQRLNAGFPDDRVFYDKWRTVQYNQRQEYLLSQFTQSKPTAVTVAKVIGQEGWKGNHPKPEEIVSLWKPALKVTIEKDEIIIKSVSQQSWSGLAIKDFGPVRGQGVVATKRFSKGDIVCDYHGKVISGTSGRQIMEDIRDKSGYLFFFKAGQRDFCIDARTFPCECHPDKVSFGRKINHSSKMANLKLVHCVMKINGKDTDVVLFKALQDIDVNTHLKFDHKFISF", "length": 596, "header": "tr|A0A8M6Z6A4-1|A0A8M6Z6A4_DANRE Isoform 1 of Uncharacterized protein si:dkey-23a23.2 OS=Danio rerio OX=7955 GN=si:dkey-23a23.2 PE=4 SV=1 CANONICAL=A0A8M6Z6A4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 413, "start_aa": "Thr", "end_pos": 413, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr413", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100034534", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100034534", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z6A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6A4" }, { "id": "PS50280", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50280" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SET", "eco_id": "ECO_0000259", "start_pos": 461, "end_pos": 592, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 413 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 245, "end_pos": 247 }, { "start_pos": 548, "end_pos": 550 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z6D8-1", "uniprot_ac": "A0A8M6Z6D8", "uniprot_id": "A0A8M6Z6D8_DANRE", "mass": { "chemical_mass": 34509.0, "monoisotopic_mass": 34509.0 }, "refseq": { "ac": "NP_001139084", "name": "uncharacterized protein LOC572312", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139084" }, "gene_names": [ { "name": "si:ch73-41e3.7", "type": "recommended", "evidence": [ { "id": "A0A8M6Z6D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8" } ] }, { "name": "si:ch73-41e3.7", "type": "synonym", "evidence": [ { "id": "NP_001139084", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139084" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC572312", "type": "synonym", "evidence": [ { "id": "A0A8M6Z6D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8/entry#names_and_taxonomy" } ] }, { "name": "protein FAM172A-like", "type": "synonym", "evidence": [ { "id": "NP_001139084", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139084" } ] }, { "name": "uncharacterized protein LOC572312", "type": "synonym", "evidence": [ { "id": "NP_001139084", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139084" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01036571.1, EH538567.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476744, SAMEA4476768 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000001.1. On Mar 5, 2009 this sequence version replaced XP_701111.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001139084", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139084" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6D8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch73-41e3.7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-163", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "572312", "url": "https://www.ncbi.nlm.nih.gov/gene/572312", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR048263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053858", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053858", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:572312", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:572312", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SAGTQCH", "url": "https://omabrowser.org/oma/group/SAGTQCH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z6D8", "url": "https://www.orthodb.org/?gene=A0A8M6Z6D8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21357", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21357", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21357:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21357:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22749", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22749", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001139084", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139084", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6D8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JE83", "url": "https://www.uniprot.org/uniprotkb/A0AC58JE83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JE83-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JE83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JE93", "url": "https://www.uniprot.org/uniprotkb/A0AC58JE93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JE93-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JE93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-163", "url": "https://zfin.org/ZDB-GENE-090313-163", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMSEFPESSDSEFPYSFSADGRLRHTHTGEPYRFQFHLRDALQTETEQRRLCRFLTQHVYTLLQQNFQMRLEEHCSVFMTPGALEHAGCLLLLLQDRGTVRGGLWSWKITAHEGLETGSQIPYLRWALMENYAVIIMNPNGDLHNKTPEEHVSEVWRRLVCVSAAQHVFVVAHGYGGLAFVDLLCCRMEEVQRRVTAVAFLDSSHSLWHQPLGKAGRDWLRCHSRTWILSTKALNRSVGSLKAGCTQISAGTQCHDSAPAVCMESVFRFFSKTIKPKATPTPFEIITRSRSRSHDHNNNNKH", "length": 302, "header": "tr|A0A8M6Z6D8-1|A0A8M6Z6D8_DANRE Isoform 1 of Uncharacterized protein LOC572312 OS=Danio rerio OX=7955 GN=si:ch73-41e3.7 PE=4 SV=1 CANONICAL=A0A8M6Z6D8-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z6D8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8/entry#A0A8M6Z6D8-1", "sequence": { "sequence": "MMSEFPESSDSEFPYSFSADGRLRHTHTGEPYRFQFHLRDALQTETEQRRLCRFLTQHVYTLLQQNFQMRLEEHCSVFMTPGALEHAGCLLLLLQDRGTVRGGLWSWKITAHEGLETGSQIPYLRWALMENYAVIIMNPNGDLHNKTPEEHVSEVWRRLVCVSAAQHVFVVAHGYGGLAFVDLLCCRMEEVQRRVTAVAFLDSSHSLWHQPLGKAGRDWLRCHSRTWILSTKALNRSVGSLKAGCTQISAGTQCHDSAPAVCMESVFRFFSKTIKPKATPTPFEIITRSRSRSHDHNNNNKH", "length": 302, "header": "tr|A0A8M6Z6D8-1|A0A8M6Z6D8_DANRE Isoform 1 of Uncharacterized protein LOC572312 OS=Danio rerio OX=7955 GN=si:ch73-41e3.7 PE=4 SV=1 CANONICAL=A0A8M6Z6D8-1" }, "locus": {} }, { "isoform_ac": "A0AC58JE83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8/entry#A0AC58JE83-1", "sequence": { "sequence": "MSCHLLQTPEEHVSEVWRRLVCVSAAQHVFVVAHGYGGLAFVDLLCCRMEEVQRRVTAVAFLDSSHSLWHQPLGKAGRDWLRCHSRTWILSTKALNRSVGSLKAGCTQISAGTQCHDSAPAVCMESVFRFFSKTIKPKATPTPFEIITRSRSRSHDHNNNNKH", "length": 163, "header": "tr|A0AC58JE83-1|A0AC58JE83_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=si:ch73-41e3.7 PE=4 SV=1 CANONICAL=A0A8M6Z6D8-1" }, "locus": {} }, { "isoform_ac": "A0AC58JE93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8/entry#A0AC58JE93-1", "sequence": { "sequence": "MMSEFPESSDSEFPYSFSADGRLRHTHTGEPYRFQFHLRDALQTETEQRRLCRFLTQHVYTLLQQNFQMRLEEHCSVFMTPGALEHAGCLLLLLQDRGTVRGGLWSWKITAHEGLETGSQIPYLRWALMENYAVIIMNPNGDLHNKTPEEHVSEVWRRLVCVSAAQHVFVVAHGYGGLAFVDLLCCRMEEVQRRVTAVAFLDSSHSLWHQPLGKAGRDWLSCFPSTLHHQCVCNVCLYSVQVSLQDVDLEH", "length": 251, "header": "tr|A0AC58JE93-1|A0AC58JE93_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch73-41e3.7 PE=4 SV=1 CANONICAL=A0A8M6Z6D8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6D8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:572312", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:572312", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GH74-1", "protein_name": "ARB2 cotranscriptional regulator A", "gene_name": "Arb2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSISLSSLIFLPIWINMAQIQQGGPNEKEKTTPLKDLLSRIDLNELMKKDEPPFDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITRYVYELLESDCNLKKISIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAVDEGYGVIVLNPNENYIEVEKQKMHKQSSSDGTDEPAGKRERKDKVSKETKKRRDFYEKYRNPQKEKEMMQLFIRENGSPEEHAVYVWDHFIAQAAAENVFFVAHSYGGLAFVELMIQREADVKSKVTAVALTDSVHNVWHQEAGKSIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTDRHELTSWKSFPSIFKFFAEASEAKSSSQKPTLTRRSHRIKHEEL", "length": 416 }, "evidence": [ { "id": "FB:FBgn0038013", "url": "https://alliancegenome.org/gene/FB:FBgn0038013#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6NC97-1", "protein_name": "Putative protein ARB2BP", "gene_name": "ARB2BP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQELSFQKFIEQSDLLGELKYDFNEKDEFRHTETQRPFVFNYYENVLEKNSKRYQALGHLLEQYIYELLEKVCKLEKVYIPPEADKEEPRSFFFMSEKALTNHHSALLILLQDHGVFRAGQWSQQAIIHHGLQHGSQIPCIQMALQAHYDVIVLNPNDNFVEPKVEKEWKGLLTQNIESSSLKMVQGGSFFSLQHPPKCIPKRCSNTPEEHTAYIWDYFISKTEGKDIAFIVHGYGGLVFMDLLVRRRWEVMSKVYAVALIDSEHHVGHQLGSDVQLLAWIKHHCREWVTSPKPLDKPAATVFKKEFPMVSAGTEKYILAPSSSLQSIFKYFKKALKARTTINFSRMPIVTRSSTKRKQSA", "length": 362 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-163#orthology", "database": "AGR" }, { "id": "HGNC:34336", "url": "https://alliancegenome.org/gene/HGNC:34336#orthology", "database": "AGR" }, { "id": "FB:FBgn0038013", "url": "https://alliancegenome.org/gene/FB:FBgn0038013#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TNH5-1", "protein_name": "Cotranscriptional regulator ARB2A", "gene_name": "Arb2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSISLSSLIFLPIWINMAQMQQGGSNETEQTAALKDLLSRIDLDELMKKDEPPFDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITRYVYELLESDCNLKKISIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAMDEGYGVIVLNPNENYIEVEKQKMHKQSSSSDGTDEPAGKRERRDKVSKETKKRRDFYEKYRNPQKEKEMMQLFIRENGSPEEHAVYVWDHFIAQAAAENVFFVAHSYGGLAFVELMIQREADVKSKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTDRHELTSWKSFPSIFKFFAEASEAKSSSQKPALTRRSHRIKHEEL", "length": 417 }, "evidence": [ { "id": "FB:FBgn0038013", "url": "https://alliancegenome.org/gene/FB:FBgn0038013#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7T297-1", "protein_name": "Cotranscriptional regulator ARB2A homolog", "gene_name": "arb2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFFRASFFLFGLVWITMAQLLAQDEKEKTTALKDLLSRIDLDELMKKDEPPLDFPETLDGFEYAFNEQGQLRHTKTGEPFVFNYKEDLHRWNQKRYEALGEIITKYVYERLEKDCNLKKEILPVDATEDEPKSFIYVSEDALSNPDKIMVLIQGSGVVRAGQWARRLIINEDLNSGTQIPFINRAKEEGYGVIVLNPNENSLEVEKVSDPAKKASPDASDEPAEKRERKEERENKKKKDFYEKYRNPQKEREMEHIPIRENGSPEEHTLYAWDYFISKSLAKNIFIVAHSYGGLSFVNLMINREAEVKSRVRAVAMTDSVHNVWHQEASKSIQDWLREHCCNWVSSPEPLDTLVDPMLNDCPRVSAGTEKHELTSWKSFQSIFKFFSNALKDHEDDSSSSPVTTRSSHRIKHEDF", "length": 415 }, "evidence": [ { "id": "FB:FBgn0038013", "url": "https://alliancegenome.org/gene/FB:FBgn0038013#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8WUF8-1", "protein_name": "Cotranscriptional regulator ARB2A", "gene_name": "ARB2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSISLSSLILLPIWINMAQIQQGGPDEKEKTTALKDLLSRIDLDELMKKDEPPLDFPDTLEGFEYAFNEKGQLRHIKTGEPFVFNYREDLHRWNQKRYEALGEIITKYVYELLEKDCNLKKVSIPVDATESEPKSFIFMSEDALTNPQKLMVLIHGSGVVRAGQWARRLIINEDLDSGTQIPFIKRAVAEGYGVIVLNPNENYIEVEKPKIHVQSSSDSSDEPAEKRERKDKVSKETKKRRDFYEKYRNPQREKEMMQLYIRENGSPEEHAIYVWDHFIAQAAAENVFFVAHSYGGLAFVELMIQREADVKNKVTAVALTDSVHNVWHQEAGKTIREWMRENCCNWVSSSEPLDTSVESMLPDCPRVSAGTDRHELTSWKSFPSIFKFFTEASEAKTSSLKPAVTRRSHRIKHEEL", "length": 416 }, "evidence": [ { "id": "FB:FBgn0038013", "url": "https://alliancegenome.org/gene/FB:FBgn0038013#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q95RN0-1", "protein_name": "FAM172 family protein homolog CG10038", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWSRLIQIFRPLRSFRMSHSPPPASNCEEALIQLKNFGYAFDGEGVLRKVDPATGEPGKELFSYNVSDDAAENEKHYQKLANQIPEIVYALLEKNGLSRTYIPFDQPPERSSFVFSQPAKLSQSKKLLVLIHGSGYVKAGQWARSLIINNSLDHGTQLPYVRQAQKLGYDLLITNANDCTRFYNGKENPIKGVNTSVEHVKYVWKNIVLPAKPESVAIVAHSYGGSLTLDLVERFPDFFKESVFAIAFTDAAMGSPQAKNKEYLCDVACDWVASNTPLDTPVSQSKSSIRRISAGHTKHEWTSYSAIDSVFKFIEEKYEQRANKK", "length": 325 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-163#orthology", "database": "AGR" }, { "id": "HGNC:34336", "url": "https://alliancegenome.org/gene/HGNC:34336#orthology", "database": "AGR" }, { "id": "FB:FBgn0038013", "url": "https://alliancegenome.org/gene/FB:FBgn0038013#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6D8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulatory ncRNA-mediated heterochromatin formation", "id": "GO:0031048", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031048", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6D8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z6D8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6D8" }, { "id": "PF22749", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22749" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Arb2", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 140, "start_aa": "Glu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 235, "end_pos": 237 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M6Z6F3-1", "uniprot_ac": "A0A8M6Z6F3", "uniprot_id": "A0A8M6Z6F3_DANRE", "mass": { "chemical_mass": 133113.0, "monoisotopic_mass": 133113.0 }, "refseq": { "ac": "XP_017211149", "name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211149" }, "gene_names": [ { "name": "LOC100329650", "type": "recommended", "evidence": [ { "id": "A0A8M6Z6F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6F3" } ] }, { "name": "LOC100329650", "type": "synonym", "evidence": [ { "id": "XP_017211149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211149" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017211149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211149" }, { "id": "A0A8M6Z6F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6F3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017211149.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211149" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6F3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6F3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100329650", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6F3", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z6F3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z6F3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100329650", "url": "https://www.ncbi.nlm.nih.gov/gene/100329650", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100329650", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100329650", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z6F3", "url": "https://www.orthodb.org/?gene=A0A8M6Z6F3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017211149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211149", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6F3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6F3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JAF5", "url": "https://www.uniprot.org/uniprotkb/A0AC58JAF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JAF5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JAF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSRVSSSVSLKSDQSKDGHPPDLREKTPSSVKSVRSGSCVSSSVSLKSDRSMGHPPPDLREKTPSSARRHLVADLVSSSDNLQWIFQNLESKMIRFLKNQLENFRKILQHKNRQEFIKEFNENRSRITEAALDLTLFFLREMKQDQAADTLQDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDQQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKTQAEKSRDESMTDFLKTAVDKALESENGHLDLFLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLLYCLNELNDQTLLKEIQSHLSSGSLSSAHLSPAQWSALVFVLLTSKEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQSCNLTVQSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLAMCNLTVQCCESLSSALQSSNCVLRKLDLSNNDLQDGLKSQHCKLETLRLVMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKYVCFLTLDPNTAHTQLIQSEENREVKRVSEDQPYPDHPDRFDYYPQVLCRESVCGRCYWEIDWSGDDVVSISVSYKSIRSKGDGVECMFGCNAQSWSLICSSSSFSFRHNNTHTVLPVKRLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCAGFGFYYPGSSVKLS", "length": 1175, "header": "tr|A0A8M6Z6F3-1|A0A8M6Z6F3_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3-like isoform X1 OS=Danio rerio OX=7955 GN=LOC100329650 PE=4 SV=2 CANONICAL=A0A8M6Z6F3-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z6F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6F3/entry#A0A8M6Z6F3-1", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSRVSSSVSLKSDQSKDGHPPDLREKTPSSVKSVRSGSCVSSSVSLKSDRSMGHPPPDLREKTPSSARRHLVADLVSSSDNLQWIFQNLESKMIRFLKNQLENFRKILQHKNRQEFIKEFNENRSRITEAALDLTLFFLREMKQDQAADTLQDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDQQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKTQAEKSRDESMTDFLKTAVDKALESENGHLDLFLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLLYCLNELNDQTLLKEIQSHLSSGSLSSAHLSPAQWSALVFVLLTSKEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQSCNLTVQSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLAMCNLTVQCCESLSSALQSSNCVLRKLDLSNNDLQDGLKSQHCKLETLRLVMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKYVCFLTLDPNTAHTQLIQSEENREVKRVSEDQPYPDHPDRFDYYPQVLCRESVCGRCYWEIDWSGDDVVSISVSYKSIRSKGDGVECMFGCNAQSWSLICSSSSFSFRHNNTHTVLPVKRLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCAGFGFYYPGSSVKLS", "length": 1175, "header": "tr|A0A8M6Z6F3-1|A0A8M6Z6F3_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3-like isoform X1 OS=Danio rerio OX=7955 GN=LOC100329650 PE=4 SV=2 CANONICAL=A0A8M6Z6F3-1" }, "locus": {} }, { "isoform_ac": "A0AC58JAF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6F3/entry#A0AC58JAF5-1", "sequence": { "sequence": "MAEERVKDSLSEKHSSVSLKSDQSKDGHPPDLREKTPSSVKSVRSGSCVSSSVSLKSDRSMGHPPPDLREKTPSSARRHLVADLVSSSDNLQWIFQNLESKMIRFLKNQLENFRKILQHKNRQEFIKEFNENRSRITEAALDLTLFFLREMKQDQAADTLQDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDQQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKTQAEKSRDESMTDFLKTAVDKALESENGHLDLFLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLLYCLNELNDQTLLKEIQSHLSSGSLSSAHLSPAQWSALVFVLLTSKEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQSCNLTVQSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLAMCNLTVQCCESLSSALQSSNCVLRKLDLSNNDLQDGLKSQHCKLETLRSELGQLID", "length": 867, "header": "tr|A0AC58JAF5-1|A0AC58JAF5_DANRE Computationally mapped isoform of NLR family CARD domain-containing protein 3-like isoform X2 OS=Danio rerio OX=7955 GN=LOC100329650 PE=4 SV=1 CANONICAL=A0A8M6Z6F3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100329650", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100329650", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6F3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6F3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6F3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6F3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1109, "end_pos": 1111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 765, "end_pos": 767, "annotation": "n_glycosylation_sequon" }, { "start_pos": 823, "end_pos": 825, "annotation": "n_glycosylation_sequon" }, { "start_pos": 873, "end_pos": 875, "annotation": "n_glycosylation_sequon" }, { "start_pos": 977, "end_pos": 979, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z6F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6F3" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 983, "end_pos": 1175, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z6F3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6F3" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 259, "end_pos": 393, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1109, "end_pos": 1111 }, { "start_pos": 141, "end_pos": 143 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 673, "end_pos": 675 }, { "start_pos": 765, "end_pos": 767 }, { "start_pos": 823, "end_pos": 825 }, { "start_pos": 873, "end_pos": 875 }, { "start_pos": 977, "end_pos": 979 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z6G2-1", "uniprot_ac": "A0A8M6Z6G2", "uniprot_id": "A0A8M6Z6G2_DANRE", "mass": { "chemical_mass": 122893.0, "monoisotopic_mass": 122893.0 }, "refseq": { "ac": "XP_017211173", "name": "NLR family CARD domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211173" }, "gene_names": [ { "name": "si:ch211-237a4.2", "type": "recommended", "evidence": [ { "id": "A0A8M6Z6G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6G2" } ] }, { "name": "si:ch211-237a4.2", "type": "synonym", "evidence": [ { "id": "XP_017211173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211173" } ] } ], "protein_names": [ { "name": "NLR family CARD domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "XP_017211173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211173" }, { "id": "A0A8M6Z6G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6G2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017211173.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211173" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6G2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6G2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-237a4.2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6G2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-504", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-504", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z6G2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z6G2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100034537", "url": "https://www.ncbi.nlm.nih.gov/gene/100034537", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z6G2", "url": "https://www.orthodb.org/?gene=A0A8M6Z6G2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017211173", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211173", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6G2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-504", "url": "https://zfin.org/ZDB-GENE-060503-504", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEDKHTSDDQDLFAACSSVNQRRTEADPSCVSMKSDWSMDEPIHFRSKNKRPALRVRSGSCMSSSVSLKSDRSKNLPPEFREKTPSSAKRFKYELADSGDETHRSHKSFTDNLQWIFQNLECKLIKFLKNELEKFKKILQDENRKEFVKDFNDNRCSITEAALDLTLFFLREMKQDKAADTLVGELFFINQLKCSLKKKYQSVFEGIAQQGDSRLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRNQPLEMKVKCKHLFEAAEQDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDNSLIFPLPFREMNLMEKENQSLKDLITRFFPETKGLNLTRSTQFKVLFILDGLDECRLPLNFAGNKTCCGVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDCQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISANVLQNILKLKHRAHAESLQESPKTLTQMYTHFVRFQIQQSRRKYDGENTPDVSWDPNLILSLGKLAFQQLDRNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGMILGTMYCFLHLSIQEFIAALYQHLILDSDKKQAEKNRNESMIDLLKTAVDKALESDNGHLDLYLRFLIGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSKGSLSSADLSPAQWSAVAFVLLTSEKELEEFELQKFKKSDECLIRLSAVIKSSKRALLQCCNLTVQCCESLSSALQSSKCILIELDLSNNDLQDSGVKLLSDGLKSSNCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNVNHGGEKRITAGLLKYACFLTLDPNTANTQLILSEENREVKCVLENQQYPDHPDRFDRVPQVLCRESVCGRSYWEIDWSGDEGVCISVSYKSISRKGYCKECWFGSNTQTWCLSCSSYSFSFTHNNRVTNLPVKSISRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFSVDYGSSVKLC", "length": 1079, "header": "tr|A0A8M6Z6G2-1|A0A8M6Z6G2_DANRE Isoform 1 of NLR family CARD domain-containing protein 3 OS=Danio rerio OX=7955 GN=si:ch211-237a4.2 PE=4 SV=3 CANONICAL=A0A8M6Z6G2-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z6G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6G2/entry#A0A8M6Z6G2-1", "sequence": { "sequence": "MEDKHTSDDQDLFAACSSVNQRRTEADPSCVSMKSDWSMDEPIHFRSKNKRPALRVRSGSCMSSSVSLKSDRSKNLPPEFREKTPSSAKRFKYELADSGDETHRSHKSFTDNLQWIFQNLECKLIKFLKNELEKFKKILQDENRKEFVKDFNDNRCSITEAALDLTLFFLREMKQDKAADTLVGELFFINQLKCSLKKKYQSVFEGIAQQGDSRLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRNQPLEMKVKCKHLFEAAEQDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDNSLIFPLPFREMNLMEKENQSLKDLITRFFPETKGLNLTRSTQFKVLFILDGLDECRLPLNFAGNKTCCGVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDCQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISANVLQNILKLKHRAHAESLQESPKTLTQMYTHFVRFQIQQSRRKYDGENTPDVSWDPNLILSLGKLAFQQLDRNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGMILGTMYCFLHLSIQEFIAALYQHLILDSDKKQAEKNRNESMIDLLKTAVDKALESDNGHLDLYLRFLIGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSKGSLSSADLSPAQWSAVAFVLLTSEKELEEFELQKFKKSDECLIRLSAVIKSSKRALLQCCNLTVQCCESLSSALQSSKCILIELDLSNNDLQDSGVKLLSDGLKSSNCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNVNHGGEKRITAGLLKYACFLTLDPNTANTQLILSEENREVKCVLENQQYPDHPDRFDRVPQVLCRESVCGRSYWEIDWSGDEGVCISVSYKSISRKGYCKECWFGSNTQTWCLSCSSYSFSFTHNNRVTNLPVKSISRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFSVDYGSSVKLC", "length": 1079, "header": "tr|A0A8M6Z6G2-1|A0A8M6Z6G2_DANRE Isoform 1 of NLR family CARD domain-containing protein 3 OS=Danio rerio OX=7955 GN=si:ch211-237a4.2 PE=4 SV=3 CANONICAL=A0A8M6Z6G2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3B2F7-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-13n15.11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEEEKSFSSKSSVFLGREKECGTACKMSFTDEKEEESGIHNLLEKASSPVPSYVSLKSDRSMAEPPKFSDEAKHFPLSHSEKEEQKCAVHYQFQGAASSLPSNVSLKSDRSMAEPPKFSHVAQHLQSSLSEKVEVCAVHHRRLSSTISSYVSLKSDRSMAEPPRFSDASEQFKYGHRVVQDQPECPQPGSSSAGEQLNIFQSVDEISQRIKEHHKTSIKQKYESLCEGFNKQENKTLLNKIYTQLYIIEGEREGVNEEHEVVQIEKAKTERLQGTPINCNDIFQPVHDPCYGRSDEKDKVRTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFLFVLPFRELNLVKDDQYSLHKLLLDFHPELLEINTRIYDLCKVLFVFDGLDESRITLTFSHCEKISDVSTSSSVSMLLSNLIKGELLPSALIWITSRPAAASHIPSHYISRVTEVQGFSDPQKEEYFRKRISNQDQASRIISHIRAARSLHIMCHIPVFCCITATVLQNILEQDLSAEIPKTLTEMYIHFLIIQTDVKRQKFDQNVEGIEKDLKLLLEASRDLILKLAELAFKGLMNGHVLFYDEDLKACGIDVNEACVHSGFCTEFFDEESVIKSRKVYCFVHLSFQEFFAALFVFSSYLNKSSDVLKIFQKKKGRRKVKLQSDEVSLDVFLNGVVDEALKSDNGHLDLFLRFLHGLLLESNQRLLQGLLTHMEDDPESMTKAMKNLKQSQKQNVRPERWINLSHCLIEMKDTSVSEDIQAYLKNEGKRKIYLSSPHCSALANMLLMAEDVLEELDLKKYNTTSMQALRRLIPAVRNCRKAILVGCNLTEQSCETVASALQPANSPVRELDMSNNDLQDSGVKLISVGLKSSHCKLEILRLKCCKLTMQCCETVASALLSANSRLRELDLSYNELQDSGVEWLAAGLKSPHCKLEILSLSGCKLTSQSCEVLASVLQSEGSRLGQLDLNNNDLQDSGLELLSAGLKICKLEKLRLATCNLTSQSCKTMAASLQSVNCVLKELDLSNNDLQDSGVEILSAGLKSPHCKLEILRLSICNLSDRSCATVASVLQSANCLRELNLSKNDLQDSGVKMLSDGLKSSLCVLEILRMSGCFITEDGCSVLASVLNSKPTHLRELDLSCNHPGDLGVQLLTARLNDQTCKLEILNLEHEGKFRIAAGLRRYACDLTLDPDTAHTHLSLSDGNRTVTHVAEEQSYPDHPDRFECCPQVLCAESLRGRCSWEAEWSGKSGVYISASYKGIRRKGQSDDCEFGSNDKSWRLVCSDNSFLAWHNNERTKMRPPSSSSRSKRVGVYLDWPAGTLSFYSISDKNKLTHLHTFSSTFSEPLYAGFGLYSGTSVSLCPIETQKTVAMT", "length": 1368 }, "evidence": [ { "id": "RGD:1307446", "url": "https://alliancegenome.org/gene/RGD:1307446#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TPT2-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:ch211-227p7.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDNSKGGPPPNFSEKTPSSVKRFFHLGKSKHPPSNLREKTPSSAESFEYESPDSKNKTHRSRKSFTDNLLKIFQNLESKMIKFLKKELQKFRKILQEENRQEFVKDFNENRSIIKEAALELTLFFLREMTQDQAADTLEDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRAVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLLFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTPDVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNVKTQAEKSRDESMIDYLKTAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDDRDQSNEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSGGSLSSARLSPAQWSALVFVLLTSEEELEKFELQKFQRSDECLIRLSAVIKTSKRALLQGCNLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGEEKRITAGIHKYVCFLTLDPNTANTQLILSEENREVKSVRENQPYPDHPDRFDYWPQVLCRESVCGRCYWEIDWSGDDHGVFISVSYKSIRRKGTGVECGFGSNAQSWSLLCSSSSFSLRHNNTHTDLPVELLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFRIYYGSSVKLS", "length": 1065 }, "evidence": [ { "id": "RGD:1307446", "url": "https://alliancegenome.org/gene/RGD:1307446#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQT1-1", "protein_name": "LOW QUALITY PROTEIN: uncharacterized protein zmp:0000001020", "gene_name": "zmp:0000001020", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSAEDVFVCVGPKSSASSCVSVKSDGSMRHPPDLSEETCNIRQEESRTASCPEPSCVSMKSDGSMRHPPDLSAEPATSEPLNKSLVRTRQRSEPSCVSVKSDGSMRHPPDLSAEAVTSDHLVDRDDQTNTLKRVSRQQVDQLQQVKDEHKASMKDKYESLYEPVKLQDNQTLLNSIYTQLYIIEGESEWVKDEDFEKSPTAQQSQDTLIYCNDIFKTSSQVKDEIRVVLTKGIAGIGKTVSVQKFILDWSEGRANQDVDFLFVLPFRELNMIKDHQYSLHSLLRDFHPKLQNLDSRIYEQCRVVFIFDGLDESRITLNFSDCEKVCDVNESSSVGVLTSNLIRGDLLPSALIWITSRAAAASQIPSKYINRVTEIQGFDEPQKREYFTRRIGNEEQANTIISHVRKARSLHIMCHIPVFCCISATVLENIITRGSEIPQSLTEMYIHFLLIQIHVNNQKYEERDPEKVLESNRGLIVKLAELAFRQLMKGNVMFYEEDLTESGMDIDAAVYSGICTAFKQELVIQQRKVYSFIHLSFQEFLAAFYAFYCHLTKNRKPLQEFLREEYSQQDRKSPRSSLYELLTSAADKTLKSKNGRLDLFLRFLLGISLESNQRLLKDLLTHTESSTDTIGETAQYIKQRVNCYNLSADRSINLFLCLLEVNDQTLSREIQEFIRSDKHSEEKLSPVHCSAIAHMIQMSEEVLEEFEPIKYNTSYEGRWRLIPAVLNCRKALLTGXCLSDEHCDSLSSALQSANSHLIELDISTNDLLISGVSQLCDALKSSHCQLRILRLAGCRLSDQDCKSLSSVLQFPNSPLRELDLSNNDLQESKLELLCAGLEDSHCQLNTLRLSGCCLSDKHCGTLASALQSSNSCLRELELSNNDVQDSGVKLLSAALKSSHCQLNTLRLAGCRLTGQCCESLSSALQSSNSKLRGLDLSNNNLQDSGVMLLSAGLKSSRCQLETLRLAICDLTGVSCESLSSALQSTECLRELDLSNNDLQDSGLKRLSAGLESLHCQLETLRLSGCMVSEDGCRYASAALSSTHSRLTELDLSYNHPGASGVSLLSDLQKNPNSALDKIHVDHGGEFRITAGLWKYACDLTLDPKTANSNLTLSEDSRKVTYVEEKQSYPDHPERFDGWPQVLCREGLSGRCYWEAEWTGYAVISVAYKAIWRKGWNEFSEFGYNRNNRNSWSLICDEAFTACHDHKETVIRVPSSSWRRVGVYVDCSAGTLSFYSVSNTLTHLHTFTCKFTEPLYAGFGIYRLNSSVSLCKFEATHIHARD", "length": 1281 }, "evidence": [ { "id": "RGD:1307446", "url": "https://alliancegenome.org/gene/RGD:1307446#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TTA3-1", "protein_name": "Uncharacterized protein si:dkey-240n22.1", "gene_name": "si:dkey-240n22.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVKSDWSKEDPPEFSEETPSPAQSEGSGSCVSSSVSLKSNWSKNHPPTLTGKEPSSAKSVEYELPEPRHRTHRRHKSFTDNLLWIFQNLENKIDRFLKNELEKFKKILQEENRQDFVKNFNDNRCRITEAALDLTLFFLRDMKQDEVADTLQGELFFINQLKCSMKKKYQSVFEGNAQQGDSTLLNTIYTDLYITQGASEQVNTEHEIRQIEVASRCHQSLEMKIECKHLFEAAEQDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDEFRLPLNFVGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIQGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNVLTEKRNIELKNRTCAETLQESPKSLTQMYIHFLCFQIQQSRRKYDGENTANASWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKDKGIILGTVYCFLHLSIQEFIAALYEHLFLDSDKKVLSSFRKRRKNKGMIDLLKAAVDKALESDNGHLDLFLRFLLGLSLQSNRQLLQGLLTQQDDSDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLREGSLSSADLSPAQWSAVAFVLLTSEEQLEDFELQKFKKSDECLIRLSAVIKTSKRALLQCCNLTVRSCESLCSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLEILRLVMCKLTPQSCQNLSSAILSSNCVLRELDLSNNDLQDSGVKFLSGGLKSPNCKLEIVRLCMCNLTAQSCESLSSALQSSNWFLRELDLSNNDLQDSGVKKLSDGLKSPICKLEILRLCICKLTVRSCESLSSVLQSSNCVLRELDLSNNDLQDSGVRLLSDGLKSPNCKLETLRVSTCHLSVQSCKSLSSVLQSSNGVLRELDLSNNDLQDSGVKLLSDGLKSPNCKLETLRLCMSNLTAQSCESLSSALQSSNCVLRELDLNDNDLQDSGVKKLSDGLKSPNCKLKTLRLSGCMVTEEGCGLLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDTLNVDHGGENRITAGLHKYACFLTLDPNTANTRLILSEENREVKRVLEKQPYPDHPDRFNCPQVLCRESVCGRCYWEIDWSGDDYVFISVSYKSIRRKGRGDECVFGQNDHSWSLICCPDSYAIMHNNRCIELPEELISSRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFRVDYPGSSVKLC", "length": 1368 }, "evidence": [ { "id": "RGD:1307446", "url": "https://alliancegenome.org/gene/RGD:1307446#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LF28-1", "protein_name": "NLR family, pyrin domain containing 5", "gene_name": "Nlrp5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPPEKDDKAKPRDEDSEKEQISESTMTPPRKDDEAIPKDEGSEKEQTTETKMTPPEKDAEMVTKVKGPEQEQTTESPTTPPKKDDKATPKEEGSEEEQKPPESPTTPPKKDDKATPKEEDSEQEQKSPESTITPEKDDKGTQKDEGSEEEQPSSESPTTPPKKDDKATTKEEGSEEEQKPPESPTTPPKKDDKATPKEEGSEKEQKSPESTTTPPKKDDKATPEEEGSEKEQKSPDSPTTPPKKDDKATLNEEGSEKEHKSPESTTPPKKDDKATPKEEGSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKSPESTTPPKKDDKATPKEEGSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKSPESTTPPKKDDKATPEEERSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKPPESTTPPKKDDKATPKEEGSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKPPESTTTPPKKDDKAIPKKEGSEEEQISPESKTTPPEKGAKMIPEFQGPEQEQTSESPTTPPKKDDKAIPKDEGSEKEQTSESKITPEKSDKASPKDKGSEEEQTSESKITPPRKDDKAIPKGERSEEEQTSPESKITPEKSDKASPKDKGSEEEQTSESKITPPRKDDKAIPKEERSEEEQTSSESTTTPPKKDDKAIPKKEGSEEEQISPESKTTPPEKGAKMIPEFQGPEQEQTSESPTTPPKKDDKAILKDEGSEEEQISESKITPPRKDDKAIPKEERSEEEQTSSGLAEERIVTPEKHDKATQKDQGSEEEQIPESTTTPPEKDDEAIPKDEGSEEEQISDYKAHVIAKFDTSVDLHCDGPEMKVLSDAFKPHQKTFRPHTIILHGRPGVGKSALARSIILGWAQGKLYQDMSYVFLFSVREMKWTEKSSLAQLMANEWPHSQAPVTKIMSQPERLLFVIDGLDDMDSALQHDDMTLSRDWKDKQPIYILVYSLLRKALLSQSFLIITTRNTGLENLRSMVVSPLYILVEGLSASRRSQLVLENIPDDHQKIQVFHSVIENHQLFDQSQAPSFCSLVCEALQLQEKLGKRCTLPCQTLTDLYATLVFHQLTSRGPSQRALSKEEQITLVGLCRMALEGVWTMRSVFYDDDLKSYSLKQSEISALFHVNILLQVGHSSEQCYVFFDLSLQDFFAALYYVLEGLGEWNQYFSYITNQRNIMEVKRSSDSHLLEMKRFLFGLMNKDTLKTVEVLFRCPVTPPIKQKLQHCLSLIGQQVNGSSPMDTLDAFYYLFESQDEEFVHMALKSFQEVWLLINQKMDLMVSSYCLQQCQNLKAIRVDISDLFSVDNTPKLCPVALQKTQCKPLIIEWWENFCTVLSTHPNLKTLDLGHSILNEWSMKILCLKLRNSSCSIQNLTFKNSEVVSGLQYLWMLLVSNRNLKYLNLGNTPMKDDDIKLACEALKHPSCSLETLRLDSCELTLTGYELISKLLLSASSLKCLSLARNKVGVKSMTSLGEALSSSTCTLQKLILDGCDLIPVSCHMLTSALSSNRNLTHLCLSNNSLGTEEVQQLCQFLKKPECALRRLILNHCNIIKDAYGFLALILANNRKLTHLSLTMNPVGNSAMKLLCEALKEPTCYLQDLELVDCQLTENCCEDLACMITTTKHLQSLDLGNNALGDKGVITLCKGLKQSSSSLRRLGLAACGLTSKCCEVLSSALSCNPYLNSLNLVRNDFNTSGMLKLCSAFQNPASNLWIIGLWKQQFYAQVRRQLEEVQFIKPHVVIDGDWYSIDEDDRNWWKN", "length": 1778 }, "evidence": [ { "id": "RGD:1307446", "url": "https://alliancegenome.org/gene/RGD:1307446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-504", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-504#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58HLY0-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:ch211-278p9.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MIFIAESESTGCKMSLYEREKEGVSVTRCKAAFPEPSCVSMKSDASLPVPPNLSDKASDFDTMNQYEKREKGSLMCKAASPEPSCVSMKSDASLPVPPNLSDGAVTSDSDTMNQYEKREKESLMCKAASPEPSCVSMKSDASLPVPPNLSDGAVTSDSDVRKDNVSRAGVPNLTYQETFIKQHKTETLQRVINQHKTSMKNRYERLFEGIKLDGNQTLLNSIYTQLYIIEGESKGVKEEHEILLMETIEKMARMKGILIKRQYTPMETQDTPIHCNSIFKPLHKPTNEGFVKDQMKTVLTKGIAGIGKTVSVQKFILDWSEGKASQDVDFMFVLPFRELNLIKDHQYSLHTLLLDFHPELQDLDSEMYEECKVVFIFDGLDESRITLKFSNIERVSDVNESSSVAVLMSNLIRGDLLPSAHIWITSRPAAANQIPSKYINRLTEIQGFNELQKEEYFRKRISDEHQANKIISHIRRSRSLHIMCHIPVFCWISATVLQKLLNEDDKAEIPQTLTEMYIHFLLTQINMRNQKYEERDPERLLKSSKDMILKLAELAYKQLMEGNVMFYEEDLIESGIDITDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAALFLFYSYAVKKRTSLKFFLSNVYDLQSHEISLYDLLKFAVKKSLRSRNGHLDLFLRFLLGVFLESNQRLLKDLLTYTEKSSESIKTITQYIKDKLKTNKDRLADRSINLFLCLLEIKDQTLYREIQDFVKSQTCSEENLSLSHCSAIAYMLQISEEVLNEFDLKKYNTSDGGKRRLIPAVVNCRKALFAGCNLTAQCCESLFSSLQTSNSLRELDLSNNGLQDSGVKLLSDGLKSSHCQLEILRLTSCQLSGQCCESLSSFLQSSNSMRELDLSNNDLQDSGVKLLSDVLKSSHCQLEILRLSGCMVTEVGCCFLASALRLNPSHLRELDLSYNHPGESLAEMLDSPNYRLDTLNVDHGAEFRITTGPQKYAFDLTLDVNTAHVNLALSEGNRKVTRVAKKQSYPDHPERFDEWCQVLSRESLTGHCYWEAEFSGRADVAVTYRGIRRKGLQTESLFGFNEKSWNLNCFDNKFIVRHKNTNRDIDKYSKSDSNRVGVYLDRSAGTLSFYSVSDTHTLKLLHTFNTTFTEPLCAAFGVFPDVSVSLLCNSKASECNNKDTQVTYTE", "length": 1182 }, "evidence": [ { "id": "RGD:1307446", "url": "https://alliancegenome.org/gene/RGD:1307446#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P59047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 5", "gene_name": "NLRP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVAGGLELGAAALLSASPRALVTLSTGPTCSILPKNPLFPQNLSSQPCIKMEGDKSLTFSSYGLQWCLYELDKEEFQTFKELLKKKSSESTTCSIPQFEIENANVECLALLLHEYYGASLAWATSISIFENMNLRTLSEKARDDMKRHSPEDPEATMTDQGPSKEKVPGISQAVQQDSATAAETKEQEISQAMEQEGATAAETEEQEISQAMEQEGATAAETEEQGHGGDTWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDSDRWGFRPRTVVLHGKSGIGKSALARRIVLCWAQGGLYQGMFSYVFFLPVREMQRKKESSVTEFISREWPDSQAPVTEIMSRPERLLFIIDGFDDLGSVLNNDTKLCKDWAEKQPPFTLIRSLLRKVLLPESFLIVTVRDVGTEKLKSEVVSPRYLLVRGISGEQRIHLLLERGIGEHQKTQGLRAIMNNRELLDQCQVPAVGSLICVALQLQDVVGESVAPFNQTLTGLHAAFVFHQLTPRGVVRRCLNLEERVVLKRFCRMAVEGVWNRKSVFDGDDLMVQGLGESELRALFHMNILLPDSHCEEYYTFFHLSLQDFCAALYYVLEGLEIEPALCPLYVEKTKRSMELKQAGFHIHSLWMKRFLFGLVSEDVRRPLEVLLGCPVPLGVKQKLLHWVSLLGQQPNATTPGDTLDAFHCLFETQDKEFVRLALNSFQEVWLPINQNLDLIASSFCLQHCPYLRKIRVDVKGIFPRDESAEACPVVPLWMRDKTLIEEQWEDFCSMLGTHPHLRQLDLGSSILTERAMKTLCAKLRHPTCKIQTLMFRNAQITPGVQHLWRIVMANRNLRSLNLGGTHLKEEDVRMACEALKHPKCLLESLRLDCCGLTHACYLKISQILTTSPSLKSLSLAGNKVTDQGVMPLSDALRVSQCALQKLILEDCGITATGCQSLASALVSNRSLTHLCLSNNSLGNEGVNLLCRSMRLPHCSLQRLMLNQCHLDTAGCGFLALALMGNSWLTHLSLSMNPVEDNGVKLLCEVMREPSCHLQDLELVKCHLTAACCESLSCVISRSRHLKSLDLTDNALGDGGVAALCEGLKQKNSVLARLGLKACGLTSDCCEALSLALSCNRHLTSLNLVQNNFSPKGMMKLCSAFACPTSNLQIIGLWKWQYPVQIRKLLEEVQLLKPRVVIDGSWHSFDEDDRYWWKN", "length": 1200 }, "evidence": [ { "id": "RGD:1307446", "url": "https://alliancegenome.org/gene/RGD:1307446#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R1M5-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 5", "gene_name": "Nlrp5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPPEKESKAILKARGLEEEQKSERKMTSPENDSKSIQKDQGPEQEQTSESTMGPPEKESKAILKARGLEEEQKSERKMTSPENDSKSIQKDQGPEQEQTSESTMGPPEKDSKAILKARGLEEEQKSESTMSPSENVSRAILKDSGSEEVEQASERKMTSPENDSKSIQKDQGPEQEQTSETLQSKEEDEVTEADKDNGGDLQDYKAHVIAKFDTSVDLHYDSPEMKLLSDAFKPYQKTFQPHTIILHGRPGVGKSALARSIVLGWAQGKLFQKMSFVIFFSVREIKWTEKSSLAQLIAKECPDSWDLVTKIMSQPERLLFVIDGLDDMDSVLQHDDMTLSRDWKDEQPIYILMYSLLRKALLPQSFLIITTRNTGLEKLKSMVVSPLYILVEGLSASRRSQLVLENISNESDRIQVFHSLIENHQLFDQCQAPSVCSLVCEALQLQKKLGKRCTLPCQTLTGLYATLVFHQLTLKRPSQSALSQEEQITLVGLCMMAAEGVWTMRSVFYDDDLKNYSLKESEILALFHMNILLQVGHNSEQCYVFSHLSLQDFFAALYYVLEGLEEWNQHFCFIENQRSIMEVKRTDDTRLLGMKRFLFGLMNKDILKTLEVLFEYPVIPTVEQKLQHWVSLIAQQVNGTSPMDTLDAFYCLFESQDEEFVGGALKRFQEVWLLINQKMDLKVSSYCLKHCQNLKAIRVDIRDLLSVDNTLELCPVVTVQETQCKPLLMEWWGNFCSVLGSLRNLKELDLGDSILSQRAMKILCLELRNQSCRIQKLTFKSAEVVSGLKHLWKLLFSNQNLKYLNLGNTPMKDDDMKLACEALKHPKCSVETLRLDSCELTIIGYEMISTLLISTTRLKCLSLAKNRVGVKSMISLGNALSSSMCLLQKLILDNCGLTPASCHLLVSALFSNQNLTHLCLSNNSLGTEGVQQLCQFLRNPECALQRLILNHCNIVDDAYGFLAMRLANNTKLTHLSLTMNPVGDGAMKLLCEALKEPTCYLQELELVDCQLTQNCCEDLACMITTTKHLKSLDLGNNALGDKGVITLCEGLKQSSSSLRRLGLGACKLTSNCCEALSLAISCNPHLNSLNLVKNDFSTSGMLKLCSAFQCPVSNLGIIGLWKQEYYARVRRQLEEVEFVKPHVVIDGDWYASDEDDRNWWKN", "length": 1163 }, "evidence": [ { "id": "RGD:1307446", "url": "https://alliancegenome.org/gene/RGD:1307446#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6G2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6G2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6G2", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6G2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 686, "end_pos": 688, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" }, { "start_pos": 882, "end_pos": 884, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z6G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6G2" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 889, "end_pos": 1079, "start_aa": "Asn", "end_aa": "Cys", 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by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_017211222.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211222", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211222" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6H8#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6H8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108183928", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6H8", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z6H8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z6H8", "database": "AlphaFoldDB", "categories": [] }, { "id": "108183928", "url": "https://www.ncbi.nlm.nih.gov/gene/108183928", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108183928", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108183928", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z6H8", "url": "https://www.orthodb.org/?gene=A0A8M6Z6H8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24390:SF260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24390:SF260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017211222", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211222", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z6H8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6H8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"UniProtKB", "id": "A0A8M6Z6H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6H8" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6H8" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6H8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z6H8", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z6H8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": 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"synonym", "evidence": [ { "id": "XP_017211728", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211728" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211728", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211728" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z715", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z715" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC795147", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z715", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z715", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z715", "database": "AlphaFoldDB", "categories": [] }, { "id": "795147", "url": "https://www.ncbi.nlm.nih.gov/gene/795147", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": 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"header": "tr|A0A8M6Z715-1|A0A8M6Z715_DANRE Isoform 1 of Chemerin-like receptor 1 OS=Danio rerio OX=7955 GN=LOC795147 PE=3 SV=1 CANONICAL=A0A8M6Z715-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z715-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z715/entry#A0A8M6Z715-1", "sequence": { "sequence": "MSVNSTESIDYDIIIEKLKTINENQVSLPINITKPKDIRHEVGMAYFIIYCIILIHGITLNFSIIVFGCCKHKSLPKAAIWIMALAATHLASCVSVVFQLLYVYNDFNWNYGDVSCKLSSYFTYGSMFSTASMLSLWSISSIFSNSACFNKSKNCNVILISFAWTIAAILACPSLFSREVREKQCIDDYDLDDNSETADGIKRLQTVVVMRFLTGLLLPALIIFVSCCVASKTRKCKLCKKQAEIIFAIKIIYFVCWAPQIFLTMLQATVSNSLGLDMLNYGLPAVTMLAMCHCFISPLFYVFLGRSLKMEWMIHDPYEDHRRSDGESLPLNN", "length": 333, "header": "tr|A0A8M6Z715-1|A0A8M6Z715_DANRE Isoform 1 of Chemerin-like receptor 1 OS=Danio rerio OX=7955 GN=LOC795147 PE=3 SV=1 CANONICAL=A0A8M6Z715-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:795147", "name": "", "url": 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"url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z715", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z715" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z715", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z715" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 301, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z762-1", "uniprot_ac": "A0A8M6Z762", "uniprot_id": "A0A8M6Z762_DANRE", "mass": { "chemical_mass": 105706.0, "monoisotopic_mass": 105706.0 }, "refseq": { "ac": "XP_017211830", "name": "rho guanine nucleotide exchange factor 15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211830" }, "gene_names": [ { "name": "arhgef15a", "type": "recommended", "evidence": [ { "id": "A0A8M6Z762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z762" } ] }, { "name": "arhgef15a", "type": "synonym", "evidence": [ { "id": "XP_017211830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211830" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 15", "type": "synonym", "evidence": [ { "id": "A0A8M6Z762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z762/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor 15", "type": "synonym", "evidence": [ { "id": "XP_017211830", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211830" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017211830", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211830" } ] } ], "disease": [ { "disease_id": "DOID:0061235", "recommended_name": { "id": "DOID:0061235", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0061235", "name": "brain small vessel disease 5 with osteoporosis", "description": "A brain small vessel disease characterized by onset of neurologic symptoms in adulthood. Features include cognitive decline, psychiatric disturbances, osteoporosis with frequent fractures, and cerebral infarctions associated with brain imaging abnormalities, including lacunal infarcts, microbleeds, enlarged perivascular spaces, white matter abnormalities, and brain atrophy that has_material_basis_in heterozygous mutation in the ARHGEF15 gene on chromosome 17p13." }, "synonyms": [ { "id": "MONDO:0979880", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0979880", "name": "brain small vessel disease 5 with osteoporosis", "description": "" }, { "id": "MIM:621331", "resource": "MIM", "url": "https://www.omim.org/entry/621331", "name": "Brain small vessel disease 5 with osteoporosis", "description": "Brain small vessel disease 5 with osteoporosis" } ], "unlinked_id_list": [], "evidence": [ { "id": "0061235", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061235" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z762", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z762" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "arhgef15a", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z762", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-292", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-292", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z762", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z762", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01221", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01221", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11793", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11793", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101882903", "url": "https://www.ncbi.nlm.nih.gov/gene/101882903", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101882903", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882903", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z762", "url": "https://www.orthodb.org/?gene=A0A8M6Z762", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12845:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12845:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017211830", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017211830", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z762", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z762", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z762-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z762-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-292", "url": "https://zfin.org/ZDB-GENE-060526-292", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MHSERASMMDKSIHKISNGKPTIPQKPILPPKPNLKTLHKTSQLASSSRVAQVLHNFEPGMDNQMALNCTRKDRRYSKDISQDEKHLGVEARLQCPTSTDDKALDIPSVTKSEHKELEVKLKADEINHQLAVDAGRSAPDGSEVNNSVSGNSDICQDSTAPPTMSEEKHCHCVCHLQRPGMKLVWVPLQEENNYLDTVNEKCNRHQNSGRQRTKLQKKEGVLHLTSNEVGKLENRTTHHSKPIQELPPCINCQSFLYHHSPHKLALKRFAYAEEPIQNHSKPPLPPRTYQSSKYQNIKQYAQHTDANIYLDLLPSKDNILTTPPVPPRPLPRPPLHPTSKQKTEKRSSQPSLACVISLRGGYPPIRNISPCKSRRLPDSTAESYENAEGWESIDKEKLSDNTGSPRRISSDWEPNSDYEPLYQIYQAKLSKEDSQIQTVSPDCNRRSVSETLGLEGHGSLGVVGTQSKRGPEEITLWQDLPVVKESGMLHKLTRTEKQRQESMFEVLTSEASYLRSLRVLKDHFLGSRELNETLVIHDRKVLFSNLLQVYEVSERFIRDLLKRVDESVVISDVSDIIYEHSENHFSVYIDYVRNQQYQEKTYSKLMESNTDFAVVMRRLELSPLCKRLPFTSFMLLPFQRITRIKILIQSIQKRTAKGTKEEETASKALTSVSKLITQANQQVGQMKQMEELINTSNKLEFDKVKVIPIVSKTRCLEKHGELQELSKRGSLFSMRNRCSPVYMFLFNDLLILTTRKSGCPDRFTVIDYAHRSLVQVQATVNSLGPHLDHCFSLTLLENHRGSTCEHLLKANTESDMHRWIAAFPSINETFGEEKIYEDWDCPQVQCVDRYVAQQADELSLEVSEVINVLRKTNEGWYEGIRLFDGKKGWFPAENTLEITTDHQRRRNVREKYQIAQSTSQNSQS", "length": 924, "header": "tr|A0A8M6Z762-1|A0A8M6Z762_DANRE Isoform 1 of Rho guanine nucleotide exchange factor 15 OS=Danio rerio OX=7955 GN=arhgef15a PE=4 SV=1 CANONICAL=A0A8M6Z762-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z762-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z762/entry#A0A8M6Z762-1", "sequence": { "sequence": "MHSERASMMDKSIHKISNGKPTIPQKPILPPKPNLKTLHKTSQLASSSRVAQVLHNFEPGMDNQMALNCTRKDRRYSKDISQDEKHLGVEARLQCPTSTDDKALDIPSVTKSEHKELEVKLKADEINHQLAVDAGRSAPDGSEVNNSVSGNSDICQDSTAPPTMSEEKHCHCVCHLQRPGMKLVWVPLQEENNYLDTVNEKCNRHQNSGRQRTKLQKKEGVLHLTSNEVGKLENRTTHHSKPIQELPPCINCQSFLYHHSPHKLALKRFAYAEEPIQNHSKPPLPPRTYQSSKYQNIKQYAQHTDANIYLDLLPSKDNILTTPPVPPRPLPRPPLHPTSKQKTEKRSSQPSLACVISLRGGYPPIRNISPCKSRRLPDSTAESYENAEGWESIDKEKLSDNTGSPRRISSDWEPNSDYEPLYQIYQAKLSKEDSQIQTVSPDCNRRSVSETLGLEGHGSLGVVGTQSKRGPEEITLWQDLPVVKESGMLHKLTRTEKQRQESMFEVLTSEASYLRSLRVLKDHFLGSRELNETLVIHDRKVLFSNLLQVYEVSERFIRDLLKRVDESVVISDVSDIIYEHSENHFSVYIDYVRNQQYQEKTYSKLMESNTDFAVVMRRLELSPLCKRLPFTSFMLLPFQRITRIKILIQSIQKRTAKGTKEEETASKALTSVSKLITQANQQVGQMKQMEELINTSNKLEFDKVKVIPIVSKTRCLEKHGELQELSKRGSLFSMRNRCSPVYMFLFNDLLILTTRKSGCPDRFTVIDYAHRSLVQVQATVNSLGPHLDHCFSLTLLENHRGSTCEHLLKANTESDMHRWIAAFPSINETFGEEKIYEDWDCPQVQCVDRYVAQQADELSLEVSEVINVLRKTNEGWYEGIRLFDGKKGWFPAENTLEITTDHQRRRNVREKYQIAQSTSQNSQS", "length": 924, "header": "tr|A0A8M6Z762-1|A0A8M6Z762_DANRE Isoform 1 of Rho guanine nucleotide exchange factor 15 OS=Danio rerio OX=7955 GN=arhgef15a PE=4 SV=1 CANONICAL=A0A8M6Z762-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101882903", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882903", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JTU0-1", "protein_name": "Rho guanine nucleotide exchange factor 15", "gene_name": "Arhgef15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAQSLPAATPPTLKPPRIIRPRPPSRHRAPHSPGPPHNGSSPKALPQISNDASASVCTSIFWEPPTGSLKPPALLPPSVSRASLDSQTSPDSPSSTPSPSPVSRRSISPEPAPCSPVPPPKPSGSSRTPLPLGPVPLQDGSASAPGTVRRLAGKFEWGAEGKAQSADSLERCSQGSTDVNGEKETLQVGLSGNGSQENGTPDAALACPPCCPCVCHVAKPGLELRWVPVGSSDDILRAPCRASPLRASRSRINPPVISHPPVVLTSYRSTAERKLLPPLKPPKPTRVRQDTSTSGELPQPDLELPSEDGIQAAPKAWEGDRPEEAPQNAPPPVALEGREEEGLEGLKELQWELPLQDEPLYQTYRAAVLSEELWGVGEDGGPSPANPGEAPTFSRLPGPRNTLWQELPAVRGSGLLESLSPQERRMQESLFEVVTSEASYLRSLRLLTDTFVLSQALRDTLTPRDHHTLFSNVQRVQSVSERFLGTLLSRVRSSPHISDLCDVVHAHAVGPFSVYVDYVRNQQYQEETYSRLMDTNVRFSAELRRLQSLPKCERLPLPSFLLLPFQRITRLRMLLQNILSQTEEGSSRQENAQKALGAVSKIIERCSAEVGRMKQTEELIRLTQRLRFHKVKALPLVSWSRRLELQGELTELGCRRGGVLFTSRPRFTPLCLLLFSDLLLITQPKSGQRLQVLDYAHRSLVQAQQVPDPSGPPTFRLSLLSNHQGRPTHRLLQAASLSDMQRWLGAFPTPGPLPCSPDTIYEDCECSQELCSEPSTPSKTEGQSLESKAPRKHLHKNPEGWLKGLPGAFPAQLVCEVTGEHERRKHLRQHQKLLEAAGPSSDTPDTPQP", "length": 850 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060526-292", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-292#orthology", "database": "AGR" }, { "id": "HGNC:15590", "url": "https://alliancegenome.org/gene/HGNC:15590#orthology", "database": "AGR" }, { "id": "MGI:3045246", "url": "https://alliancegenome.org/gene/MGI:3045246#orthology", "database": "AGR" }, { "id": "RGD:1306961", "url": "https://alliancegenome.org/gene/RGD:1306961#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A1D2-1", "protein_name": "Rho guanine nucleotide exchange factor 26", "gene_name": "Arhgef26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGESEVDFSSNGVTPLWRRRSTPPLQLLGRSKPRPQSYQSPSGLLITDFPVEELAALPAPQTPVPVPAGPEGRTVSRSPQLLCAHRRPVTNGRTVSPDYRAASPRLRRPKSPLVSYAASGGSPKSAVNGTVSSPAALLSRASRTPDIPASSAPGEDRTRVTASKVSSPTANGLAPKTDSSGPVSQTGQSAGDLEPSPSRLSPAPQHRSSEQKLPLQRLPSQGNELPNPSVILSTNSPAALKMGKQQIIPKSLASEIKLSKSNSQNVEPHRRLLKVRSMVEGLGAPLGPEGEESEADNDIDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKAVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEEPEPKEQKPEEKIVIHHKPLRSTWSQLSAVKRNGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKDSKELTDTMTKTERHHLFSNITDVWEASKKFFTELEARHQNNIFIEDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLTTNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSKRMSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNTSTMLYSRQSSATHLFTLTVLSNHANEKVDMLLGAETQSERARWITALGHSSGKQPPDRTTLTQVEITRSFTAKQPDELSLQVADVVLIYQRVGDGWYEGERLRDGERGWFPMECAKEITCQATIDKNVERMGRLLGLETNV", "length": 869 }, "evidence": [ { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O94989-1", "protein_name": "Rho guanine nucleotide exchange factor 15", "gene_name": "ARHGEF15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAQSLPAATPPTQKPPRIIRPRPPSRSRAAQSPGPPHNGSSPQELPRNSNDAPTPMCTPIFWEPPAASLKPPALLPPSASRASLDSQTSPDSPSSTPTPSPVSRRSASPEPAPRSPVPPPKPSGSPCTPLLPMAGVLAQNGSASAPGTVRRLAGRFEGGAEGRAQDADAPEPGLQARADVNGEREAPLTGSGSQENGAPDAGLACPPCCPCVCHTTRPGLELRWVPVGGYEEVPRVPRRASPLRTSRSRPHPPSIGHPAVVLTSYRSTAERKLLPLLKPPKPTRVRQDATIFGDPPQPDLDLLSEDGIQTGDSPDEAPQNTPPATVEGREEEGLEVLKEQNWELPLQDEPLYQTYRAAVLSEELWGVGEDGSPSPANAGDAPTFPRPPGPRNTLWQELPAVQASGLLDTLSPQERRMQESLFEVVTSEASYLRSLRLLTDTFVLSQALRDTLTPRDHHTLFSNVQRVQGVSERFLATLLSRVRSSPHISDLCDVVHAHAVGPFSVYVDYVRNQQYQEETYSRLMDTNVRFSAELRRLQSLPKCERLPLPSFLLLPFQRITRLRMLLQNILRQTEEGSSRQENAQKALGAVSKIIERCSAEVGRMKQTEELIRLTQRLRFHKVKALPLVSWSRRLEFQGELTELGCRRGGVLFASRPRFTPLCLLLFSDLLLITQPKSGQRLQVLDYAHRSLVQAQQVPDPSGPPTFRLSLLSNHQGRPTHRLLQASSLSDMQRWLGAFPTPGPLPCSPDTIYEDCDCSQELCSESSAPAKTEGRSLESRAAPKHLHKTPEGWLKGLPGAFPAQLVCEVTGEHERRRHLRQNQRLLEAVGSSSGTPNAPPP", "length": 841 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060526-292", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-292#orthology", "database": "AGR" }, { "id": "HGNC:15590", "url": "https://alliancegenome.org/gene/HGNC:15590#orthology", "database": "AGR" }, { "id": "MGI:3045246", "url": "https://alliancegenome.org/gene/MGI:3045246#orthology", "database": "AGR" }, { "id": "RGD:1306961", "url": "https://alliancegenome.org/gene/RGD:1306961#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5BKC9-1", "protein_name": "Ephexin-1", "gene_name": "Ngef", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKNSEDQGKPQRKSVSSLWKSKHGPAEMRPELPPETAKETQNEEPRCLIPIQRNSLFNRAMRHKHKARSMSERRANDQAGDLPETRKSVNEPLAFNLPQGRLPPWRTPAQRGPGAQEASESSSTPGNGTTPEECPALTDSPTTLTEALQMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIQGNSDGSQAGEDNAEEEEEEEEEPASPPERRALPQICLLSNPHSRFNLWQDLPEIQSSGVLDILQPEETKLQEAMFELVTSEASYYKSLNLLVSHFMENERLKKILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKTAFRELIAQLELDPKCKGLPLSSFLILPFQRITRLKLLVQNILKRVEEGSEREGTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMEDPQRSQNKDRRKLGSRNRQ", "length": 701 }, "evidence": [ { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5FWH6-1", "protein_name": "Rho guanine nucleotide exchange factor 15", "gene_name": "Arhgef15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAQSLPAATPPTLKPPRIIRPRPPSRHRAPHSPGPLHNGSSPKALPQISNDASASVCTSIFWEPPTASLKPPALLPPSVSRTSLDSQTSPDSPSSTPSPSPVSRRSISPEPAPCSPVPPPKPSGSSRTPLPSGPTPLQDGSASAPGTVRRLAGKFEWGAEGKAQSSDSLERCSQGSTEVNGEKETPEAALSGNGSQENGTPDAALACPPCCPCVCHVAKPGLELRWVPVGSSEDILRIPCRASPLRASRSRINPPVISHPPVVLTSYRSTAERKLLPPLKPPKPTKVRQDISTSEELPQPDLKLPSEDGIQTATKAWEGDRPEGAPLNAPPVALEGREEEGLDGLKGLQWELPLQDEPLYQTYRAAVLSEELWGVGEDGGPSPANPGEAPTFSRLPGPRNTLWQELPAVRGSGLLESLSPQERRMQESLFEVVTSEASYLRSLRLLTDTFVLSQALRDTLTPRDHHTLFSNVQRVQSVSERFLGTLLSRVRSSPHITDLCDVVHAHAVGPFFVYVDYVRNQQYQEETYSRLMDTNVRFSAELRRLQSLPKCERLPLPSFLLLPFQRITRLRMLLQNILSQTEEGSSRQENAQKALGAVSKIIERCSAEVGRMKQTEELIRLTQRLRFHKVKALPLVSWSRRLELQGELTELGCRRGGVLFTSRPRFTPLCLLLFSDLLLITQPKSGQRLQVLDYAHRSLVQAQQVPDPSGPPTFRLSLLSNHQGRPTHRLLQAASLSDMQRWLGAFPTPGPLPCSPDTIYEDCECSQELCSEPSTPSKTEGQSLESKAPRKHLHKNPEGWLKGLPGAFPAQLVCEVTGEHERRKHLRQHQKLLEAVGPSSGTPDTPQP", "length": 849 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060526-292", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-292#orthology", "database": "AGR" }, { "id": "HGNC:15590", "url": "https://alliancegenome.org/gene/HGNC:15590#orthology", "database": "AGR" }, { "id": "MGI:3045246", "url": "https://alliancegenome.org/gene/MGI:3045246#orthology", "database": "AGR" }, { "id": "RGD:1306961", "url": "https://alliancegenome.org/gene/RGD:1306961#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BWA8-1", "protein_name": "Rho guanine nucleotide exchange factor 19", "gene_name": "Arhgef19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDCGPPATLQPHLAGPPGTARRPVAVCQQESLSFVELPPSRLCVDLFPIAPEELQAPGSRWSLATPAPLQGLLWPTSPGGPDTHIASTSGGMRPGRAGSWPHCPGAQPPTLVEPWSSQHMQPQRRASHSGSEKSAWRKMQVYHNEEATGTETPTGLLETGQAAQEQALCALEPGPQELSGNARGGLEAPERRRFSASELMTRLHSSLRLGRSTATRVLTSGSGAGAIREGKLPVRESRRAETRADSVSLPGPVDLNEVHGGLVEPRLDTQDKPTQDPSSATERRQSRFLLNSVLYQEYSDVASARELRRQQREEEGPGDGAEGAEEGPGPPRANLSPSSSFRAQRSTRGSTFSLWQDIPDVRGSGVLATLSLRDCKLQEAKFELITSEASYIHSLSVAVGHFLGSVELSECLGTQDKQWLFSKLPEVKSTSERFLHDLEQRLEADVLRFSVCDVVLHHCPAFRRVYLPYVTNQAYQERTYQRLLLENPKFPGILARLEESPVCQRLPLTSFLILPFQRVTRLKMLVENILKRTAPGSQDEDMATKAFSALKELVQECNASVQSMKRTEELIHLSKKIHFEGKIFPLISQARWLVRHGELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLLLSRRKELGKFAVFVHANMAELQVRDLSLKLQGIPGHVFLLRLLHGQRARHQLLLRARTESEKQRWISALRPSSPQEDKEITCDGEDRPQVQCVRTYKALQPDELTLEKTDILAVKTRTSDGWLEGVRLADGEKGWVPQAHVVEISSLSARLRNLREYKRVSNASSKLGDPPA", "length": 802 }, "evidence": [ { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CHT1-1", "protein_name": "Ephexin-1", "gene_name": "Ngef", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METKNSEDWGKPQRKSESSSRKSNHGPAEMRPALPPENREAPETGEETQNEEPRRLIPIQRHSLFNRAVRHRHKARSTSERRASDQADLPKMGKSVNERSAFNLPQGRLSPWRTPAQRDTGAQEASESSSTPGNGTTPEECPALTDSPTTLTEALQMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIQGNSDGSQVGEDAGEEEEEEEEGEEEELASPPERRALPQICLLSNPHSRFNLWQDLPEIQSSGVLDILQPEEIRLQEAMFELVTSEASYYKSLNLLVSHFMENERLKKILHPSEAHILFSNVLDVMAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCKGLPFSSFLILPFQRITRLKLLVQNILKRVEERSEREGTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFREIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILEKTEDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMEDPQRSQNKDRRKLGSRNRQ", "length": 710 }, "evidence": [ { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IW93-1", "protein_name": "Rho guanine nucleotide exchange factor 19", "gene_name": "ARHGEF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDCGPPATLQPHLTGPPGTAHHPVAVCQQESLSFAELPALKPPSPVCLDLFPVAPEELRAPGSRWSLGTPAPLQGLLWPLSPGGSDTEITSGGMRPSRAGSWPHCPGAQPPALEGPWSPRHTQPQRRASHGSEKKSAWRKMRVYQREEVPGCPEAHAVFLEPGQVVQEQALSTEEPRVELSGSTRVSLEGPERRRFSASELMTRLHSSLRLGRNSAARALISGSGTGAAREGKASGMEARSVEMSGDRVSRPAPGDSREGDWSEPRLDTQEEPPLGSRSTNERRQSRFLLNSVLYQEYSDVASARELRRQQREEEGPGDEAEGAEEGPGPPRANLSPSSSFRAQRSARGSTFSLWQDIPDVRGSGVLATLSLRDCKLQEAKFELITSEASYIHSLSVAVGHFLGSAELSECLGAQDKQWLFSKLPEVKSTSERFLQDLEQRLEADVLRFSVCDVVLDHCPAFRRVYLPYVTNQAYQERTYQRLLLENPRFPGILARLEESPVCQRLPLTSFLILPFQRITRLKMLVENILKRTAQGSEDEDMATKAFNALKELVQECNASVQSMKRTEELIHLSKKIHFEGKIFPLISQARWLVRHGELVELAPLPAAPPAKLKLSSKAVYLHLFNDCLLLSRRKELGKFAVFVHAKMAELQVRDLSLKLQGIPGHVFLLQLLHGQHMKHQFLLRARTESEKQRWISALCPSSPQEDKEVISEGEDCPQVQCVRTYKALHPDELTLEKTDILSVRTWTSDGWLEGVRLADGEKGWVPQAYVEEISSLSARLRNLRENKRVTSATSKLGEAPV", "length": 802 }, "evidence": [ { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N5V2-1", "protein_name": "Ephexin-1", "gene_name": "NGEF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METRESEDLEKTRRKSASDQWNTDNEPAKVKPELLPEKEETSQADQDIQDKEPHCHIPIKRNSIFNRSIRRKSKAKARDNPERNASCLADSQDNGKSVNEPLTLNIPWSRMPPCRTAMQTDPGAQEMSESSSTPGNGATPEEWPALADSPTTLTEALRMIHPIPADSWRNLIEQIGLLYQEYRDKSTLQEIETRRQQDAEIEDNTNGSPASEDTPEEEEEEEEEEEPASPPERKTLPQICLLSNPHSRFNLWQDLPEIRSSGVLEILQPEEIKLQEAMFELVTSEASYYKSLNLLVSHFMENERIRKILHPSEAHILFSNVLDVLAVSERFLLELEHRMEENIVISDVCDIVYRYAADHFSVYITYVSNQTYQERTYKQLLQEKAAFRELIAQLELDPKCRGLPFSSFLILPFQRITRLKLLVQNILKRVEERSERECTALDAHKELEMVVKACNEGVRKMSRTEQMISIQKKMEFKIKSVPIISHSRWLLKQGELQQMSGPKTSRTLRTKKLFHEIYLFLFNDLLVICRQIPGDKYQVFDSAPRGLLRVEELEDQGQTLANVFILRLLENADDREATYMLKASSQSEMKRWMTSLAPNRRTKFVSFTSRLLDCPQVQCVHPYVAQQPDELTLELADILNILDKTDDGWIFGERLHDQERGWFPSSMTEEILNPKIRSQNLKECFRVHKMDDPQRSQNKDRRKLGSRNRQ", "length": 710 }, "evidence": [ { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96DR7-1", "protein_name": "Rho guanine nucleotide exchange factor 26", "gene_name": "ARHGEF26", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGESEVDFSSNSITPLWRRRSIPQPHQVLGRSKPRPQSYQSPNGLLITDFPVEDGGTLLAAQIPAQVPTASDSRTVHRSPLLLGAQRRAVANGGTASPEYRAASPRLRRPKSPKLPKAVPGGSPKSPANGAVTLPAPPPPPVLRPPRTPNAPAPCTPEEDLTGLTASPVPSPTANGLAANNDSPGSGSQSGRKAKDPERGLFPGPQKSSSEQKLPLQRLPSQENELLENPSVVLSTNSPAALKVGKQQIIPKSLASEIKISKSNNQNVEPHKRLLKVRSMVEGLGGPLGHAGEESEVDNDVDSPGSLRRGLRSTSYRRAVVSGFDFDSPTSSKKKNRMSQPVLKVVMEDKEKFSSLGRIKKKMLKGQGTFDGEENAVLYQNYKEKALDIDSDEESEPKEQKSDEKIVIHHKPLRSTWSQLSAVKRKGLSQTVSQEERKRQEAIFEVISSEHSYLLSLEILIRMFKNSKELSDTMTKTERHHLFSNITDVCEASKKFFIELEARHQNNIFIDDISDIVEKHTASTFDPYVKYCTNEVYQQRTLQKLLATNPSFKEVLSRIESHEDCRNLPMISFLILPMQRVTRLPLLMDTICQKTPKDSPKYEVCKRALKEVSKLVRLCNEGARKMERTEMMYTINSQLEFKIKPFPLVSSSRWLVKRGELTAYVEDTVLFSRRTSKQQVYFFLFNDVLIITKKKSEESYNVNDYSLRDQLLVESCDNEELNSSPGKNSSTMLYSRQSSASHLFTLTVLSNHANEKVEMLLGAETQSERARWITALGHSSGKPPADRTSLTQVEIVRSFTAKQPDELSLQVADVVLIYQRVSDGWYEGERLRDGERGWFPMECAKEITCQATIDKNVERMGRLLGLETNV", "length": 871 }, "evidence": [ { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VVC6-1", "protein_name": "Ephexin, isoform E", "gene_name": "Exn", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAMSPVLDAAAKAAGRDLNGNSNAASATAASTATPTAAAAAAATTPRKTKKTIINWLVNSDSENNNRATCDKAGKDNPNPNQNPNSQANPNQNCSCESRAFRDFRGVQTLRLLWSRRIKSASEDQCHSPVHCHTSSSSLGTLKKLNKSVSCLVNAFNNSRDCATPEKTLAKRAASLHNLQDSQAKHKQLHREKDNFYKYKNAEQAKMQAKLRSSADEAILNASETRAKRDDSGCLPGVKSYNSKALSAADKVAKVAKGEAKTQRRAEEPVGEAEVEVEVEFRAKREHNRLEGLSLSAASAQSGGSSESLQTTTTSSSTPTTHSSVTSSTGRSGGRRKYSFKTHAGKSYHQHHHPSRRTSNMDSSNGGISMVAKLTHQFNEIIQKDAKLLEQVKRNNGVWISRGTHVYKIVEKPTSEGKGLPNADDNRISTVQRNIKKFERLEKPSVPLKSEQLMRKHLELMRGSSLSRGPRIKRNLKLPPGSVGIPELAIVSEELKTPTSEEQAKKPKSVQNESQPNHPEELNQSNDKPSDELDLIMGEEGDEEELRQKQRKHKYASIYEKLRFTFAKGRKSASPSPTKAQIREEVSIDEESIKDSTSEDMVTRKEDFTLDLPKEVIPRAEDLEDSSHALLVSPCFEADAKILDALEAVDLKLKVLNPLNDVTTADGERELLLAANDDFEQRILPNSSFVYQAANKQYSNNQILLNQAVNVTLVNAIEGEQMIMEQKQLMKVRDLELTERDIDQPLKRAEKSPEKDDTLEPESLYEPITPVMDETKTEAQTSSLFKIYTKKSELVEDIYQTVEEASTVEVKPNNWLEGYESIAGSQEACPLTYDGYESFAPEEVVTTPTTPSATGTLGRNTRDELPELPKPKRVLNKSPIPLRPAPPKPQAKESEEDENIYDTIKGCYESMHCKATSSSSSGEATLTTDTISLSSNCYESISHIRRSRVATTQNQGHGSAGSCIQLSSSGSTLTISSDHKTNSLYESSLAAAGCVVYGSASVGCRSSLGSSAGSRDSGKPGDKRSSIAGSSDNSDAWVDISDGEIGQATTDATANEAQFIVVRERFKPHRTRSPDWSKRIRDKRLQQKKAISCIEDDSDHYYETLSPLGNKRHSTQLVRQSQDGNRSGGVRSSHRRSKNHSASAHTLGEHVVISDDYDSFETDSDDHGDGEPDLRQRNYNDSGVDMRNHRLPKPPPPQNQVYEFVRKFKDFISSKKSPKGSQQKLYENTPASTLFYVECSKRTEDVYENTDFGPERIPAPETKGPVHQEQAPVLRAKQKNGKSLRSRLRKSLVGSSFDTKQLSSLAPTRSTFYVEDPEGSLPALPLEPEIHGSGELDSGFSDKNCTPLPETPKFSTVARKAKKEAKANRRRTTIGLRPNDPPPPPPPMTGNKSPLDPERELDAEQTTSWYAECGVFKQATNGAVSPRGDEPVTPTPSGHGGVSSWYAESGLYQTSGISVASSSGSSGVSTGNEAGLGDELSSEPHSLFSNEPLYQMYSAAKLESITRDLEAHGSSDGYEEIGLQAKAKPEPLVKPRPTALQLVEPKNGPSRTLWSEIPEVIHSCILPTLTSRERSLQEAKFEIITSEASYLKSLNLLRRHFMNHNAFLDSSVLSAKDRKALFSYIVPVHECSERLLTELEACWQDNIMLLGLSRCIYEIAERHFHVYVAFCEHQGRMDRTLRRLKESKESLAFQQHLERLEASPSCCGLNLHSFLMLPMQRITRLPLLIDAVFSKESPLNREEYESWKLTLALVQKVVGQCNEAANRWEQAFELERIARQLEFPSHVRALAIAPVGVPRAGAKPRFLVKRGELTHLLWRGEDAKLTFGKRLTKISIYAFLFSDLLLLCKRRGESCFSVFDYCPRSMLTLAAGDSLPQLPTKDLKDQAGKNLILMTLLENCDRKTVELVLSCPSVSDQQRWLQAMRPPEAETPGEKLYESWDCPQVVAKHSYESDEPDVLQLELGDVVNVSRKLPDGWYQGERIRDGAVGWFPGSYTEELNSAHVRARNLKQRHRLLTFTATYLESQKSK", "length": 2029 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-060526-292", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-292#orthology", "database": "AGR" }, { "id": "FB:FBgn0261547", "url": "https://alliancegenome.org/gene/FB:FBgn0261547#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of actin cytoskeleton organization", "id": "GO:0032956", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032956", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z762", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z762" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z762", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z762" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 531, "end_pos": 533, "annotation": "n_glycosylation_sequon" }, { "start_pos": 68, "end_pos": 70, "annotation": "n_glycosylation_sequon" }, { "start_pos": 694, "end_pos": 696, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z762" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 498, "end_pos": 682, "start_aa": "Gln", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z762" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 724, "end_pos": 828, "start_aa": "Glu", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z762", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z762" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", 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Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017212200.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017212200", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212200" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7J4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7J4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110437794", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7J4", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z7J4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z7J4", "database": "AlphaFoldDB", "categories": [] }, { "id": "110437794", "url": "https://www.ncbi.nlm.nih.gov/gene/110437794", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001740", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001740", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057774", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057774", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z7J4", "url": "https://www.orthodb.org/?gene=A0A8M6Z7J4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12011:SF469", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12011:SF469", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23283", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23283", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017212200", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212200", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z7J4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z7J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58FYW5", "url": "https://www.uniprot.org/uniprotkb/A0AC58FYW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58FYW5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58FYW5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTMTGIILHKRFLKGLSTISVIMQDSTLILAFLMVAPVMSTAANLTDPCYNYTVLSNSWRSVNNTNNGYNCDQSVSWSGWYRLFINGLSAHIPDTCVAVSRCGTDYPLWIRGGHPTVEDGVVTRDVCGNAGSYCCYFGSFPIGVKACPGNYYVYELLKPTTCNLAYCADVGSVINSSTAATPVIITPDPCYNYTVLDDPWRANSRQPSKPVTMCDQSVSWSGWYRLFINGLSAQIPDTCVAVYSCGTTIPLWIRGGHPTVEDGVVTRDVCGCDGGYCCYLGSYPIRVKACPGNYYVYELLRPTTCNLAYCAVVSNMSSTSTTVTPQTTSSAVINITLQEGCSNQSSGCLKNLLEQIENITAQELPLNTVTDILTVVFNASEKISVSSSSASPAQLASYGTKVLKSSEKLISTLVKPTETSANVSFTLAAVEGQVFMVGPQVTLDKIPQLDTTNSSVDIDLIGIAKNNNNRSAVAFMSYTTMENLLKADFFNTTNDTIKTMMSTVISATLPKTSNTALTKAVNFTFRHIREFDPSGSLSCVYWNISEWIVDGCSVLNSNSSHTVCSCVHLSTFALIMQTSSSPPPSDLLELLDLVCVIVGLVFFSLALLSFALCQWSPGVNNVARINICISLLSAHLLFLLTQQFLSLIRPQQVLCVAIAGLLHFLFLSAFVWMFIEAVLLFICVKNLSQISSKKREVLSSGFLCVIGYVLAMVVVCVSIGLVPEGYGSEHCWIKTDEGFIWSFLGPVCVILALNLILFIKIVITLNSTLKNLNAEVSQMKQTKVMVFKTLGQFVVLGCPWILGFFTNSSEVLEIVFLVLNSQQGTFIFLIYCVLNNEIRQQYKNCFTCLCSGHGIKCNK", "length": 859, "header": "tr|A0A8M6Z7J4-1|A0A8M6Z7J4_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110437794 PE=3 SV=3 CANONICAL=A0A8M6Z7J4-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z7J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7J4/entry#A0A8M6Z7J4-1", "sequence": { "sequence": "MTMTGIILHKRFLKGLSTISVIMQDSTLILAFLMVAPVMSTAANLTDPCYNYTVLSNSWRSVNNTNNGYNCDQSVSWSGWYRLFINGLSAHIPDTCVAVSRCGTDYPLWIRGGHPTVEDGVVTRDVCGNAGSYCCYFGSFPIGVKACPGNYYVYELLKPTTCNLAYCADVGSVINSSTAATPVIITPDPCYNYTVLDDPWRANSRQPSKPVTMCDQSVSWSGWYRLFINGLSAQIPDTCVAVYSCGTTIPLWIRGGHPTVEDGVVTRDVCGCDGGYCCYLGSYPIRVKACPGNYYVYELLRPTTCNLAYCAVVSNMSSTSTTVTPQTTSSAVINITLQEGCSNQSSGCLKNLLEQIENITAQELPLNTVTDILTVVFNASEKISVSSSSASPAQLASYGTKVLKSSEKLISTLVKPTETSANVSFTLAAVEGQVFMVGPQVTLDKIPQLDTTNSSVDIDLIGIAKNNNNRSAVAFMSYTTMENLLKADFFNTTNDTIKTMMSTVISATLPKTSNTALTKAVNFTFRHIREFDPSGSLSCVYWNISEWIVDGCSVLNSNSSHTVCSCVHLSTFALIMQTSSSPPPSDLLELLDLVCVIVGLVFFSLALLSFALCQWSPGVNNVARINICISLLSAHLLFLLTQQFLSLIRPQQVLCVAIAGLLHFLFLSAFVWMFIEAVLLFICVKNLSQISSKKREVLSSGFLCVIGYVLAMVVVCVSIGLVPEGYGSEHCWIKTDEGFIWSFLGPVCVILALNLILFIKIVITLNSTLKNLNAEVSQMKQTKVMVFKTLGQFVVLGCPWILGFFTNSSEVLEIVFLVLNSQQGTFIFLIYCVLNNEIRQQYKNCFTCLCSGHGIKCNK", "length": 859, "header": "tr|A0A8M6Z7J4-1|A0A8M6Z7J4_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110437794 PE=3 SV=3 CANONICAL=A0A8M6Z7J4-1" }, "locus": {} }, { "isoform_ac": "A0AC58FYW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7J4/entry#A0AC58FYW5-1", "sequence": { "sequence": "MTMTGIILHKRFLKGLSTISVIMHSTLILAFLMVAPVMSTAANLTDPCYNYTVLSNSWRSVNNTNNGYNCDQSVSWSGWYRLFINGLSAHIPDTCVAVSRCGTDYPLWIRGGHPTVEDGVVTRDVCGNAGSYCCYFGSFPIGVKACPGNYYVYELLKPTTCNLAYCADVGSVINSSTAATPVIITPDPCYNYTVLDDPWRANSRQPSKPVTMCDQSVSWSGWYRLFINGLSAQIPDTCVAVYSCGTTIPLWIRGGHPTVEDGVVTRDVCGCDGGYCCYLGSYPIRVKACPGNYYVYELLRPTTCNLAYCAVVSNMSSTSTTVTPQTTSSAVINITLQEGCSNQSSGCLKNLLEQIENITAQELPLNTVTDILTVVFNASEKISVSSSSASPAQLASYGTKVLKSSEKLISTLVKPTETSANVSFTLAAVEGQVFMVGPQVTLDKIPQLDTTNSSVDIDLIGIAKNNNNRSAVAFMSYTTMENLLKADFFNTTNDTIKTMMSTVISATLPKTSNTALTKAVNFTFRHIREFDPSGSLSCVYWNISEWIVDGCSVLNSNSSHTVCSCVHLSTFALIMQTSSSPPPSDLLELLDLVCVIVGLVFFSLALLSFALCQWSPGVNNVARINICISLLSAHLLFLLTQQFLSLIRPQQVLCVAIAGLLHFLFLSAFVWMFIEAVLLFICVKNLSQISSKKREVLSSGFLCVIGYVLAMVVVCVSIGLVPEGYGSEHCWIKTDEGFIWSFLGPVCVILALNLILFIKIVITLNSTLKNLNAEVSQMKQTKVMVFKTLGQFVVLGCPWILGFFTNSSEVLEIVFLVLNSQQGTFIFLIYCVLNNEIRQQYKNCFTCLCSGHGIKCNK", "length": 858, "header": "tr|A0AC58FYW5-1|A0AC58FYW5_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC110437794 PE=3 SV=1 CANONICAL=A0A8M6Z7J4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7J4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7J4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7J4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7J4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7J4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7J4" } ], "pmid": "" }, { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7J4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7J4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 686, "end_pos": 688, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z7J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7J4" }, { "id": "PS50261", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 2", "eco_id": "ECO_0000259", "start_pos": 588, "end_pos": 835, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z7J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7J4" }, { "id": "PS50221", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50221" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GAIN-B", "eco_id": "ECO_0000259", "start_pos": 433, "end_pos": 582, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 175, "end_pos": 177 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 315, "end_pos": 317 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 378, "end_pos": 380 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 469, "end_pos": 471 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 558, "end_pos": 560 }, { "start_pos": 63, "end_pos": 65 }, { "start_pos": 686, "end_pos": 688 }, { "start_pos": 766, "end_pos": 768 }, { "start_pos": 807, "end_pos": 809 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z7T5-1", "uniprot_ac": "A0A8M6Z7T5", "uniprot_id": "A0A8M6Z7T5_DANRE", "mass": { "chemical_mass": 29726.0, "monoisotopic_mass": 29726.0 }, "refseq": { "ac": "XP_021333815", "name": "E3 ubiquitin-protein ligase CCNB1IP1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333815" }, "gene_names": [ { "name": "ccnb1ip1", "type": "recommended", "evidence": [ { "id": "A0A8M6Z7T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7T5" } ] }, { "name": "ccnb1ip1", "type": "synonym", "evidence": [ { "id": "XP_021333815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333815" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase CCNB1IP1", "type": "synonym", "evidence": [ { "id": "XP_021333815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333815" }, { "id": "A0A8M6Z7T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7T5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021333815.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021333815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333815" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7T5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ccnb1ip1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7T5", "locus": {} } ], "crossref": [ { "id": "562825", "url": "https://www.ncbi.nlm.nih.gov/gene/562825", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042448", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042448", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562825", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562825", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EHMYQEY", "url": "https://omabrowser.org/oma/group/EHMYQEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z7T5", "url": "https://www.orthodb.org/?gene=A0A8M6Z7T5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14305", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14305", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14305:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14305:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14634", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14634", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021333815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333815", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7T5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z7T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7T5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNTIAKSRTSMSASKFTLLCNSHKCRVKLSGVAWVTACSHVFCDQHGSEEFSRTPAVCPACSSMLSGKLDVLRTELTPSEQYKAMVLVGLQPETVLEISHKAIDFWIYQINQERLLMEYNLSRAGGQVLQMEKFMIQQNQSREHELNALKGEISSLKKMLEEYKRKYSEVLERLNERNKQYQKLQGLLDSLRMHTMGTVEKDTVPHTFTTGLVKQRSPLSSPSFIGPEADRFFSLGPESAKTFFQFSTPTQDKTHSFIKKN", "length": 261, "header": "tr|A0A8M6Z7T5-1|A0A8M6Z7T5_DANRE Isoform 1 of E3 ubiquitin-protein ligase CCNB1IP1 OS=Danio rerio OX=7955 GN=ccnb1ip1 PE=4 SV=2 CANONICAL=A0A8M6Z7T5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z7T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7T5/entry#A0A8M6Z7T5-1", "sequence": { "sequence": "MNTIAKSRTSMSASKFTLLCNSHKCRVKLSGVAWVTACSHVFCDQHGSEEFSRTPAVCPACSSMLSGKLDVLRTELTPSEQYKAMVLVGLQPETVLEISHKAIDFWIYQINQERLLMEYNLSRAGGQVLQMEKFMIQQNQSREHELNALKGEISSLKKMLEEYKRKYSEVLERLNERNKQYQKLQGLLDSLRMHTMGTVEKDTVPHTFTTGLVKQRSPLSSPSFIGPEADRFFSLGPESAKTFFQFSTPTQDKTHSFIKKN", "length": 261, "header": "tr|A0A8M6Z7T5-1|A0A8M6Z7T5_DANRE Isoform 1 of E3 ubiquitin-protein ligase CCNB1IP1 OS=Danio rerio OX=7955 GN=ccnb1ip1 PE=4 SV=2 CANONICAL=A0A8M6Z7T5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:562825", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562825", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LMJ0-1", "protein_name": "Cyclin B1 interacting protein 1", "gene_name": "Ccnb1ip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSDSSATRILSSVEGRHLLACLATGFFGTLVMSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSHSPAICPACNSTLSGKLDIVRTELSPSEEYKAMVLAGLRPEVVLDISSRALAFWTYQVHQERLYQEYNFSKAENHLKQMEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDSLRLRNITIASQEGSLEPAMIPQSGVFGFPSGNSSKFSLDHTPAGNQGGGDEDVQFRPFFVCSPTAPEPVNNFFSFASQSHEAEQQVCSRAFKAKRI", "length": 308 }, "evidence": [ { "id": "A0A8M6Z7T5", "url": "https://omabrowser.org/oma/group/A0A8M6Z7T5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z3K2-1", "protein_name": "E3 ubiquitin-protein ligase CCNB1IP1", "gene_name": "Ccnb1ip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLDIVRTELSPSEEYKAMVLAGLRPEVVLDISSRALAFWTYQVHQERLYQEYNFSKAENHLKQMEKMYMQQIQSKNIELTSMKGEVISMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDSLRLRNITIASQEGSLEPGMIPQSGVFGFPPGNNSKFSLDHIPVGNQGGGDEDVQFRPFFVCSPTAPEPINNFFSFASPSHEAEQQVCSRAFKAKRI", "length": 276 }, "evidence": [ { "id": "A0A8M6Z7T5", "url": "https://omabrowser.org/oma/group/A0A8M6Z7T5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3I1Q4-1", "protein_name": "E3 ubiquitin-protein ligase CCNB1IP1", "gene_name": "Ccnb1ip1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSLYEDMLLCNYRKCRLKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLDIVRTELSPSEEYKAMVLAGLRPEIVLDISSRALAFWTYQVHQERLYQEYNFSKAESHLKQMEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDSLRLRNITIASQEGSLEQATIAQSGVFGFPLGNSSKFPLDHTPVGSRGGGDEDVQFRPFFVDSPTAPEPINNFFSFASQSHESEQQVCSRAFKAKRI", "length": 276 }, "evidence": [ { "id": "A0A8M6Z7T5", "url": "https://omabrowser.org/oma/group/A0A8M6Z7T5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9NPC3-1", "protein_name": "E3 ubiquitin-protein ligase CCNB1IP1", "gene_name": "CCNB1IP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLCEDMLLCNYRKCRIKLSGYAWVTACSHIFCDQHGSGEFSRSPAICPACNSTLSGKLDIVRTELSPSEEYKAMVLAGLRPEIVLDISSRALAFWTYQVHQERLYQEYNFSKAEGHLKQMEKIYTQQIQSKDVELTSMKGEVTSMKKVLEEYKKKFSDISEKLMERNRQYQKLQGLYDSLRLRNITIANHEGTLEPSMIAQSGVLGFPLGNNSKFPLDNTPVRNRGDGDGDFQFRPFFAGSPTAPEPSNSFFSFVSPSRELEQQQVSSRAFKVKRI", "length": 277 }, "evidence": [ { "id": "A0A8M6Z7T5", "url": "https://omabrowser.org/oma/group/A0A8M6Z7T5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7T5" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7T5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "reciprocal meiotic recombination", "id": "GO:0007131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007131", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7T5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "synaptonemal complex", "id": "GO:0000795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000795", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7T5", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7T5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z7T5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7T5" }, { "id": "PF14634", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14634" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 62, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 139, "end_pos": 141 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z7U4-1", "uniprot_ac": "A0A8M6Z7U4", "uniprot_id": "A0A8M6Z7U4_DANRE", "mass": { "chemical_mass": 36649.0, "monoisotopic_mass": 36649.0 }, "refseq": { "ac": "XP_017212966", "name": "fibrinogen silencer-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212966" }, "gene_names": [ { "name": "fsbp", "type": "recommended", "evidence": [ { "id": "A0A8M6Z7U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U4" } ] }, { "name": "fsbp", "type": "synonym", "evidence": [ { "id": "XP_017212966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212966" } ] } ], "protein_names": [ { "name": "Fibrinogen silencer-binding protein", "type": "synonym", "evidence": [ { "id": "A0A8M6Z7U4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U4/entry#names_and_taxonomy" } ] }, { "name": "fibrinogen silencer-binding protein", "type": "synonym", "evidence": [ { "id": "XP_017212966", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212966" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017212966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212966" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z7U4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fsbp", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U4", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z7U4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z7U4", "database": "AlphaFoldDB", "categories": [] }, { "id": "108190967", "url": "https://www.ncbi.nlm.nih.gov/gene/108190967", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028002", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028002", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108190967", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108190967", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z7U4", "url": "https://www.orthodb.org/?gene=A0A8M6Z7U4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21411", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21411", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21411:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21411:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13873", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13873", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017212966", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017212966", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z7U4", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z7U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTTMTYRMPNFTLEQKLFLLRRIHAVVDTVQDFRKDTNTTVHRNAVWAELAQAFNAAFPSRPPSSIGSLKTLWKRLKVECRVALQKRQEQQAAGLPVSALTQVQREVIALVPNLISCLEEVDGDSSYASVRGGSPGAVMGLSGTNGSEHEDADHSQNDEVDSKENLAIELGLSSPTHPPVNSGIPPGSSSSPLHSHSLSSRSSRPSFIYSTHPGSTSGHGSGARAANFDSVHREPAVARGSVENSFPPADSFTSDSKWEARRQELFEQEHQQTMSLLLLQQCVWEEKRKAVRQKEKAARAKKRYYQAKLRKIGAGHSPSSSDSDDNEQHPRT", "length": 333, "header": "tr|A0A8M6Z7U4-1|A0A8M6Z7U4_DANRE Isoform 1 of Fibrinogen silencer-binding protein OS=Danio rerio OX=7955 GN=fsbp PE=4 SV=1 CANONICAL=A0A8M6Z7U4-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z7U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z7U4/entry#A0A8M6Z7U4-1", "sequence": { 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This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017213590.1. 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF04118", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24597", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24597", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24601", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24601", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26706", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26706", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213320", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213320", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8M9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040426-1195", "url": "https://zfin.org/ZDB-GENE-040426-1195", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDPEEAELQNDYRYRSYAAVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLIIGKRLAQCLHPALPSGVHLKALETYEVIFKIIGTKWLAKDLFIYSSGLFPLLGHAAMSVKPVLLTLYERYFLPLQRALLPSLQAFIMGLLPGLEEGAEVYDRTDALLVKLSVLVGQSVFYGALWGSVLICPLVRLPASLFIVAHFDHSITAKEQKFMLGTDHRLVVKAVCLALQDSNVLVQRNTLEILLYFFPFTTFQDPGECAIPLKQDEMISVVSAASLTLLRRDMSLNRRLYAWMLGLDIKGGMGAADSSHYSTVEEYTAFYFNTHSRELLVQALVNILKQKDIEANPDNLIDYLRPFRIIISLLDKSEIGPLVLSDVLLEVVRAFYSYCIAMLGDNGNNTSLTGSQLNSKIKENKNSSEIIKTVNMLVSAMSSNFLWDYMTRHFQICLSSLRDPVEKSPSKSWSSPPSVTELSTLIIFLLDVIPLELYAEIQTQYLPQMLGNMLQSLQSHMTSLSLSELTQAMRACFKVLSKIQMPVAYMDMEAESHTQDVEQTQIMMAGNNKVKESEQVDGNQNSVSAEDGLNGQEAQEVEAGEAPYPPLRSEDSGLGLSASPSEQHLLPVLNGSEAASGVNCEAEDVWRRGGTIENMSKCVQDIMAIVITRHLLDIVDPEKKKKQEEANQLDANASPKSSKRSPLKRKGSRDLGLIKDRLAEFFNPSKLRIHALHGLSRDGGKDHRPAQLEWMGSFQSKSKGEISESCRQAFTVICQLLLECTTFPVYFTEEENQELHTSMFNKTGIEGTLPDWLRSLMTLCCLTKDYQVQHTAISSLLEMINHSQSLALVIHDKNQRYKNSDANPLSGQLQMVTLPPVYPVVLKTLEDSTDFYLRVSQVLWAQLDTERKEHHVSCVELFYRLHCLAPSASICEDIICLGLLSGDKVVCLEALHRFSVLWHLTREIQTSRSTSLNRSFDRSLFVVLDSLNNQDGSVRAAAQNWLVRALSLSDVVRILEPVLLLLLDPKTQRSPIQSIKQNLSAGNVKALIWRDRSIPKSAGDSMTPGCQTEESFVNRITIVDREALWAELERDPELTPPDSPTISQSESDETEGEDEEVEEEEESEHTESADTSGAQNSTENSSSSSAPYLQRHEDGSVEEDAVPNGLQRVDSERTQVSDSLSSDEDDGQLEAMAKTRQLKRQREKREAVDSLFRHVLLYKQKYESSQILYAFTILETILRTSAGPFVEALSSTSLDCSSIAHLNLIQNLLQRHRQAQDGGSFYGQLQNSTPPSGGTPDASQPASSPLHSPSCPPTLLLELLTSLCMRYLRSHYPSYASVPTRQLQANREVQVKSVEVLTELMIQLVRVAQQNGDTKGTAGLEAVRNLLWGYKVQQYVLLTLSASMYVCQRVDRPDQHTLPEEDQGEDGGEISEESLINFGRDGTWAEHPLQIALLKLLKVLIVLEHHVCPPHTKPQEHDQGQSNPQRRAEPPSSALAREWQTAVMFQQSIKAVRYVSSQPITAQGMFVSAAARALHPQYGCAMHPAWVTLLCDVLPYLGRSLAIIVSPIIAQICRNLDELVKQHEHDGIKGSHNGTLKRENIAPDYPLTLLEGLTTITHYCLLDHKKATAGCDVPDLRNASNAILEEFPHMISSMALLWGVVKGCDSTHGSRATPTSVYFKSTKILRQKVLEFLMPLTQQFGVQVMASVAAVWNSRKSRKRRSRNKILPDASDSQMTLVDLVKALNTLRTDTILQLIREVVKKPHQIKGDQKSTLVDIPMLQFSYVYIQSLTAQALQENINPLLCLLRESVQLNLAPPGHFLLLGILNDCVNRLPNIDNKRDTKELQEVSQRILEAVGAVAGSSLEQTSWLSRNLEVKAQPQVCLQGDEDDHDANEFEEYAGQGSTMVSSSAPSVFSVQALVLLAEVLAPLLDMVYRSDEKEKAVPLISRLMYYVFPYLKNHSAYNMPSFCAGAQLLSSLSGYAYTKRAWKKEVLELFMDPLFFTMESSCSYHWRSIIDHLLTHEKTMFKDLMSMQSSSLKLFNSAEQKPMLLKRQAFAMFSGENDQYHFYLPLIQERLTENLRVGQSPSVSAQMFLMFRVLLLRISPQHLTSLWPIMVTELIRIFNRLEKALLDDKEVTKSKLRGGHDKNGLLCFPQAELDMYLSACKFLDTAVSFPPDHMPLFQMYRWAFIPEVDVDHYDGPGNTLLEGEQECKPHIVRILDGINRRYGELNGTAAESSTDRVEFPLLTLRSLYSIVDLVPFFNTLCCSFNGSSSAHLSHYAADYPPSSSDQVMKRLEHITEGEFLDGMDS", "length": 2312, "header": "tr|A0A8M6Z8M9-1|A0A8M6Z8M9_DANRE Isoform 1 of Protein DOP1B OS=Danio rerio OX=7955 GN=dop1b PE=3 SV=1 CANONICAL=A0A8M6Z8M9-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z8M9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9/entry#A0A8M6Z8M9-1", "sequence": { "sequence": "MDPEEAELQNDYRYRSYAAVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLIIGKRLAQCLHPALPSGVHLKALETYEVIFKIIGTKWLAKDLFIYSSGLFPLLGHAAMSVKPVLLTLYERYFLPLQRALLPSLQAFIMGLLPGLEEGAEVYDRTDALLVKLSVLVGQSVFYGALWGSVLICPLVRLPASLFIVAHFDHSITAKEQKFMLGTDHRLVVKAVCLALQDSNVLVQRNTLEILLYFFPFTTFQDPGECAIPLKQDEMISVVSAASLTLLRRDMSLNRRLYAWMLGLDIKGGMGAADSSHYSTVEEYTAFYFNTHSRELLVQALVNILKQKDIEANPDNLIDYLRPFRIIISLLDKSEIGPLVLSDVLLEVVRAFYSYCIAMLGDNGNNTSLTGSQLNSKIKENKNSSEIIKTVNMLVSAMSSNFLWDYMTRHFQICLSSLRDPVEKSPSKSWSSPPSVTELSTLIIFLLDVIPLELYAEIQTQYLPQMLGNMLQSLQSHMTSLSLSELTQAMRACFKVLSKIQMPVAYMDMEAESHTQDVEQTQIMMAGNNKVKESEQVDGNQNSVSAEDGLNGQEAQEVEAGEAPYPPLRSEDSGLGLSASPSEQHLLPVLNGSEAASGVNCEAEDVWRRGGTIENMSKCVQDIMAIVITRHLLDIVDPEKKKKQEEANQLDANASPKSSKRSPLKRKGSRDLGLIKDRLAEFFNPSKLRIHALHGLSRDGGKDHRPAQLEWMGSFQSKSKGEISESCRQAFTVICQLLLECTTFPVYFTEEENQELHTSMFNKTGIEGTLPDWLRSLMTLCCLTKDYQVQHTAISSLLEMINHSQSLALVIHDKNQRYKNSDANPLSGQLQMVTLPPVYPVVLKTLEDSTDFYLRVSQVLWAQLDTERKEHHVSCVELFYRLHCLAPSASICEDIICLGLLSGDKVVCLEALHRFSVLWHLTREIQTSRSTSLNRSFDRSLFVVLDSLNNQDGSVRAAAQNWLVRALSLSDVVRILEPVLLLLLDPKTQRSPIQSIKQNLSAGNVKALIWRDRSIPKSAGDSMTPGCQTEESFVNRITIVDREALWAELERDPELTPPDSPTISQSESDETEGEDEEVEEEEESEHTESADTSGAQNSTENSSSSSAPYLQRHEDGSVEEDAVPNGLQRVDSERTQVSDSLSSDEDDGQLEAMAKTRQLKRQREKREAVDSLFRHVLLYKQKYESSQILYAFTILETILRTSAGPFVEALSSTSLDCSSIAHLNLIQNLLQRHRQAQDGGSFYGQLQNSTPPSGGTPDASQPASSPLHSPSCPPTLLLELLTSLCMRYLRSHYPSYASVPTRQLQANREVQVKSVEVLTELMIQLVRVAQQNGDTKGTAGLEAVRNLLWGYKVQQYVLLTLSASMYVCQRVDRPDQHTLPEEDQGEDGGEISEESLINFGRDGTWAEHPLQIALLKLLKVLIVLEHHVCPPHTKPQEHDQGQSNPQRRAEPPSSALAREWQTAVMFQQSIKAVRYVSSQPITAQGMFVSAAARALHPQYGCAMHPAWVTLLCDVLPYLGRSLAIIVSPIIAQICRNLDELVKQHEHDGIKGSHNGTLKRENIAPDYPLTLLEGLTTITHYCLLDHKKATAGCDVPDLRNASNAILEEFPHMISSMALLWGVVKGCDSTHGSRATPTSVYFKSTKILRQKVLEFLMPLTQQFGVQVMASVAAVWNSRKSRKRRSRNKILPDASDSQMTLVDLVKALNTLRTDTILQLIREVVKKPHQIKGDQKSTLVDIPMLQFSYVYIQSLTAQALQENINPLLCLLRESVQLNLAPPGHFLLLGILNDCVNRLPNIDNKRDTKELQEVSQRILEAVGAVAGSSLEQTSWLSRNLEVKAQPQVCLQGDEDDHDANEFEEYAGQGSTMVSSSAPSVFSVQALVLLAEVLAPLLDMVYRSDEKEKAVPLISRLMYYVFPYLKNHSAYNMPSFCAGAQLLSSLSGYAYTKRAWKKEVLELFMDPLFFTMESSCSYHWRSIIDHLLTHEKTMFKDLMSMQSSSLKLFNSAEQKPMLLKRQAFAMFSGENDQYHFYLPLIQERLTENLRVGQSPSVSAQMFLMFRVLLLRISPQHLTSLWPIMVTELIRIFNRLEKALLDDKEVTKSKLRGGHDKNGLLCFPQAELDMYLSACKFLDTAVSFPPDHMPLFQMYRWAFIPEVDVDHYDGPGNTLLEGEQECKPHIVRILDGINRRYGELNGTAAESSTDRVEFPLLTLRSLYSIVDLVPFFNTLCCSFNGSSSAHLSHYAADYPPSSSDQVMKRLEHITEGEFLDGMDS", "length": 2312, "header": "tr|A0A8M6Z8M9-1|A0A8M6Z8M9_DANRE Isoform 1 of Protein DOP1B OS=Danio rerio OX=7955 GN=dop1b PE=3 SV=1 CANONICAL=A0A8M6Z8M9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1295, "start_aa": "Thr", "end_pos": 1295, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1295", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:393582", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:393582", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A0N6-1", "protein_name": "DOP1 leucine zipper like protein A", "gene_name": "Dop1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPTLLSLYEIYYLPLGKTLKPGLQGLLTGILPGLEEGSEYYERTNTLLEKVAAAVEQSAFYSALWGSLLTSPAVRLPGITYVLAHLNRKLSMEDQLYIIGSDIELMVEAVSTSVQDSSVLVQRSTLDLILFCFPFHMSQATRPDMIRILSAALHVVLRRDMSLNRRLYAWLLGFDNNGAIIGPRSTRHSNPEEHATYYFTTFSKELLVQAMVGILQVNGFGEESTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQMEPPFSKDRAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYIARWFEECCRRTLHARLEVGPGDSSDASEFQLTTFCSLVDFLLDIVSLPTRSMRVLCQETYIEIQTEHLPQLLLRMISALTSHLQTLRLSELTDSLRLCSKILSKVQPPLLSAGTGGVVQFPSGQNSAVKEWEDKKVSSVSMENPTEVFEDGENPPSSRSSESGFTEFIQYQAERTDDLDRELNGQGTATIPIGSTSSETETASTVGSEETVIQPPSTLTQGAAGRTGKAVQKTAMQCCLEYVQQFLSRLIHLYILHSDSFPQASAADHQSDLSRIQRDTSKWDRDSQGDAKERNIHTPKTSKEYLSAFLAACQLFLECSSFPVYIAEGNHTSESHSEKPDTDCEHAHPPQWLQTLMSACSQASDFSVQSVAVSLVMDLVGLTQSVAMVTGENINSMEPAQPLSPNQGRVAVVIRPPLTQGNLRYIAEKTEFFKHVALTLWDQLGDGTPQHHQKSVELFYQLHNLVPSSSICEDVVSQQLTHKDKKVRMEAHARFAVLWHLTRDLHVNKSSFARSFDRSLFIMLDSLTSLDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWSKTSCYPGEENDKHFMQNFTCNNVSQVHLIASKGSREKPLTMDEIENFSLTVNPLSDRLSLLSTSSETIPMVVSDFDLPDQQMEILQSSDSGCSQSSAGDNFSYEVDPENVSAHEDSHLAKASSPDDDVQQVVFDLICKVVSGLEAESASVTSELEIESLPPKSSDFDLGKEATKTEDQAPQHSQHVLLSDDSPRFLSVSTEEGCECLANGISRNSSSPCISGTAQTLTDSSVSSETKSRQRSHSSIQFSFKEKLSEKISEKETIVKESGKQPGAKPKVKLARKKDEDKKKAASEKLKQTNVFFSDGLDLENWYSCGEGEISEIESDMGSPGSRKSPNFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKSILKSNPVAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIPVDSNHNFRSSMYIEILISLCLYYMRSHYPTHVKVTTQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFPSFISDMLSKCKVQKVILHCLLSSIFSVQKWHSEKTAGKNMVAVEEGFSEDSLINFSEDEFDNGSTLQSQLLRVLQRLIVLEHRVMTIPEESEAGFDFVVSDLEHVSPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGKVLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWVASIIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVNVDQKHLVEARSGILSILHMIMSSVTLLWSILHQADASEKMGLAASASVTTINLGATKNLRQQILELLGPISMNHGVHFMAAIAFVWNGRRQNKTPSRTKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAKDKKHLSLEVCMLQFFYAYIQRIPVPNLVDSWASLLVLLKDSIQLSLPAPGQFLILGVLNEFIMKNPSLENKKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETSNITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDASCVSHWRAIMDNLMTHDKTTFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAIFSSEIDQYQKYLPDIQERLVESLRLPQVPTLHSQVFLFFRVLLLRMSPQHLTSLWPTMITELVQVFLLMEQELTADEDISRTSGPSAAGLETTYTGGNGFSTSYNSQRWLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSGLEVRRQGIHQREFKPYVVRLAKLLRKRAKKNPEEDGSARTLGWEPGHLLLTLCTMRNMEQLLPFFNVLSQVFNSKVTSRCGGHSGSPILYSNSFPSKDMKLENHKAFSSKARQKIEEMIEKDFLEGVIKT", "length": 2462 }, "evidence": [ { "id": "FB:FBgn0034400", "url": "https://alliancegenome.org/gene/FB:FBgn0034400#orthology", "database": "AGR" }, { "id": "SGD:S000002548", "url": "https://alliancegenome.org/gene/SGD:S000002548#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LFK5-1", "protein_name": "DOP1 leucine zipper like protein B", "gene_name": "Dop1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPEEQELLTDYRYRSYASVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLIISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYEKYFLPLQKLLLPSLQAFLVGLLPGLEEGSEIYERTDTLLLRLSVVVGREVFYAALWGSVLTSPSIRLPASLFVVNHISRDSPGKEQKYMLGTDYQLTVRALCASLLDANVLVQRNNLEITLFFFPFYTCLDPDERAIPLLRRDIVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTIVPKSEISSSYEDQCSYFFDKYSKDLLVEALAEILHQKFLNADLEERHHEYLKPFRILVSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGPDLRLSYTQSGNLLTSTIKENRHASEIVKTVNLLVSSLSTDFLWDYMARCFEECFRPVTQTTAIGEAISPPPTVSELCTLLVFLLDVIPLELYSEVQTQYLPQVLGCLLQPLAEEVEALSLPELTHALKTCFKVLSKVQMPPSYLDMEPTSGNSSPIKGRNSGVLETEAVVAGDEEPSFPPLKSEDSGIGLSASSPELSEHLRVPRVSAERDDIWKKDGNMQATFLCIQELIANFANKNIFAASLTVSGEESKPEGAPGKSIRGQTQSTEHSGRKSSWEPKPITVPQFKQMLSDLFTVRGSPFKTRSSESLSSAPSSPHRKAAAEWDVDQVVIELVGSKEDCREALAAACHLLLDCATFPVYLSEEETQQLCEMLFQTPGPSDCSFPPWLKSLMTICCCVNDCSLQNIAIATLLEVINHSQSLALVIEDKMKRYKTSGNNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTREIQGSRVTSHNRSFDRSLFVVLDSLACTDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIQCLKQENSAEGLHRWFNRKKPACREACGESELQEGAPEEHLPRGQFTTVDREAIWAEVEKEPEKCPPRSDLSEEDLPYYVDLPDRMASGGGDSSEHTESADTSSGHTDSENTSTFSSPSHDLQDLSHEENCCAPIPVGGRAYSKRAALLAAFQPESPRSNARLSLVRADSDKTQASESFSSDEEAEVELQAITTSRLLKQQREKQETVEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALIGQSFYGKLQTQAPNVCPHSLLIELLTYLCLSFLRSYYPCYLKVCHRDILGNRDVQVKSVEVLIRITTQLVSMAKSSEGKNVEFIHSLLQRCKVQEFVLLSLSASMYTSQKRYGLATADRGGRVFVEDSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLGQGQEDSESQPALSREWQRALNFQQAIGAMQYVQPHPLTSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVIQICKNLDDLVKQYESESVKFTVSTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAVSDPINLRNAKNAILEELPRIVNTMALIWNVLKKEETQKRPVDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTGHLGVQLIAAVATVWSRKQSRRHSKTKMVPVASASQHTLVDLVCALSTLQTDSVLQLVKEVVKKPAQIKGDEKSPLVDIPVLQFCYAFIQRGGVTKVEQETVRLSIPDLQEAFPSLLGVLKEAVQLNLAPPGYFLLLSMLNDFVTRTPNLESKKDQKDLQEITQRILEAVGTIAGSSLEQTSWLSRNLEVKAQPQVSLEDSDADEDVCDAAAASTMVSASAPSIYSVQALSLLAEVLASLLDMVYRSDEKERAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYSKRAWKKEVLELFLDPAFFQMDSSCVHWKSIIDHLLTHEKTMFKDLMNMQSSSLKLFSSFEQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSIVAGQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFIQLEEDLKEEEESRNSNKINRVKVPAADGTGPSGGAVTPSDLIMYLSACKFLDTALSFPPDKMPLFQIYRWAFVPEVDTEHPAFLSELEENHQECRPHTVRILELLRLKYGEISSSEEITRKKEFPLLRQHSVSCIRQLIPFFRTLNCAFKTQSQLPADVPGTTVPEFPVADSLRVLQQLEECVEQDFLEYPEC", "length": 2306 }, "evidence": [ { "id": "MGI:1917278", "url": "https://alliancegenome.org/gene/MGI:1917278#orthology", "database": "AGR" }, { "id": "HGNC:1291", "url": "https://alliancegenome.org/gene/HGNC:1291#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1195", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1195#orthology", "database": "AGR" }, { "id": "FB:FBgn0034400", "url": "https://alliancegenome.org/gene/FB:FBgn0034400#orthology", "database": "AGR" }, { "id": "RGD:1306097", "url": "https://alliancegenome.org/gene/RGD:1306097#orthology", "database": "AGR" }, { "id": "SGD:S000002548", "url": "https://alliancegenome.org/gene/SGD:S000002548#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1ZBE8-1", "protein_name": "Protein DOP1 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MESADALVEEQKLMAEAKYRTYMTNIDKALRNFEYSSEWADLISALGKLSKAISSNTQYQVIPRRLKIAKRLAQCMHPALPSGVHLKALETYSVIFSKTGPERLATEFIYSAGLFPLLGYAAMNVRPALLAIYETYFVPLGDKLRPALSGFLNGVLPGYDCGLDHFERISALLKQVCNAVNPMHFYTVLWESVANNAAIRLPAITYLLEHFNKRLDMQEQIYIMGHNREIMMSALCVCLNDSLILVQRNTLEFLLLGFPMHTVLLSEDDLVKLVTNGLNTILRRDMSLNRRLFSWLLGSEVAKNSPTYDTLSLDTSNAPLEEEPEPYFVKHSRHILIKALITTLRLSLECAPMDLKPYRIMLSLLDKAEIGSAVLDYVLHDIIRAMYISSGNAEALKSANLLFATFDPAYIWSYMTNMFEKACQQANSMQEKSQAGETSGKYACDVGSGDPCVLEICVLTEFLLETVSLEMYTETTRVYLPKVFLAITQLLSLHMDHISSNEITASLKLCMKIVSRVQPMITSPIKLNKLIEQSGGSSSDEKITMNSASDAGKTEAGAQGNSLEKSKSDSRLNQFAENTLHSADPNDEELIHRSASNQSVGRQSPNKKKAKSISRLSELDKDISASDTGQQSSSDLDTPRSIKKLKAKAKVPFIRSPKKQRPKDMVLIQSNTSAEVSDGPSAEEPKSAPPDQTPQFQLDEESRATQQRGFSILEKCIRQYEIFFEVYLSRKLLHIESEPKECSVKVQLQRTTSTIHTSNLFMAEQVLDHECPVRESQIERLFNLLRVDIVPRSKQLQRLLNRSLPLPASASELSSDSEAQEEKQQSLLIDGQTQRSVQQLAELQLSPSLRGAVKLAATLLVEMSTFPNCNKHVVLDKNEPELPNWLKVLCLVACFAQSDKELQVASITTLFDLISLLRSQIEHTTSPGVTFVVMLPLLKFGHVSYMEQHTRVFQLVSSILWDYLGTAGIDPAQIAALLHQLHSCLESGLVETVIGNRMQSQHLLQMQSQSRSDLGKAAIRNFQMERLAEAQLLCPTESTERLRESQARSFKKFELLWHLGRDKQTARGFEKTLLKVLDTLALPHYMSERTFVTNWLQASLLRGDLARLTKPLYKILLSASSKRVGIVHMQQLYRESETEVTPAFERDVYAISSEQGNVKYHHMETSSGNKKKSPIRNFPKKIFGVTLSGGKANKVSNFVSDKSTVATCSEATQDMNTIGLIINPLENANDFDDETDLEEPRIEIPHKETPLEQKLASAMDESEQPSQEQPANQPDNSLQYDQDITDHSDSSDFESDSELRETSIEKEDSITVSSSAGVSDDVKRFVGDCESVTDALTQHEKIKSRKTYRLTREKTPGENSLNSLEQKDHDSISELQADALPADEYFREDKKLGKRKKVLTSGEKKRLSCISKTSTDSNISGSHVEQPEQEEETEPGTESTINVEDKRRNLSLETSKLQPDMQKTLEKGKQNVEILRQNNAAAAAAAAAAAEEQISVRSSMKSTVSLTDAAHLYHNHLLIYLAIYDTRQTLYALQTLRNIICCDKRTFLCLSITTSFSSASLKQLLVRHRKSISGKGFDGSVGNSEYAQGYRGCMQLELLVTLCLFYARGYFQKESLDAQRQSPTLQDIVNNRRIQLESIELLTLICSELIEIVKGMGRGLANYIADLLARAKLQKVMLHCLNSSVCSYGLKGNTNSGSYAEQVLSFNDPQDDQLHADCFQLQLLRLLLAVIRLEHEVHQLRQDTPPAAGEDSAGNASPTRLAEGATANVKYLPNCLISQQPMFLAAVLGALQQERLRHLHRNWTDLVTSSLNCFSFGSLTNIVISVVHQLCSNLDRISKMGLPQQRHFPPDYVVSQLEALTILCHYCLLDNTQQTALSHLFNQAYPQTSSSAQSSSTGQLLNSIVHSFLSASESSTSAPAPRNPQLQAARNAVLSHLPRIMSSVAAIWDSELGQLRPVRQQLLEFLSPVSLHHGSNFLAAVAVTWQQRGIATNMNGLSIAEQFQRNSVLQACPAQLSLVSLVSSIRVMPMDSFVMTLHHVVRSPPPIHRPPAQLSIEVSALELFYFYMKSAPAPQLADAWSSLLALIRDGLNLTPPAQFALLMLLNEFVQRCPQMPFQDKKEVRELHDVTSRLVDSLSSVAGSCLEQTTWLRRNLAVKEDTDGLAKDNSVGGGGLQQYSLQAQSVLAAILSNLLDVAYGSQEKDKVVNIVTPLLYNITPYLKNHTARNVPFFYACSALLASLSGYQYTRKAWRKDMLDLLLDNAFFQMHLSCLPFWRMIMDSLMTYDNTTFRELMTRVSLSQAGSLNIFTSRDQEYEQRAMLLKRLAFVIYCSEFDQHNKYMPDIQEQLANSLRLVPMGPSVQAAVFLCFRVLLLRMSPDHVTSLWPIIIAEMVQVFLQMEQELKSESEERNQQLRLPSGIDVSWSAASGASNGYNSQTPMQHWRSVQLEACKLLELGCVLPATKLPHFQMYRWAFVGTEFDVHEEEVCLPNGSLENLATLPSALYVPHVRRVARLMDMKYTSQSPILQRPSNRHLMLHFQQLQSLQELYAFFTTLGISCPQPRNFADTENDVANCLKEIEEVLANDFLEKLPSITTPR", "length": 2599 }, "evidence": [ { "id": "MGI:1917278", "url": "https://alliancegenome.org/gene/MGI:1917278#orthology", "database": "AGR" }, { "id": "HGNC:1291", "url": "https://alliancegenome.org/gene/HGNC:1291#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1195", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1195#orthology", "database": "AGR" }, { "id": "FB:FBgn0034400", "url": "https://alliancegenome.org/gene/FB:FBgn0034400#orthology", "database": "AGR" }, { "id": "RGD:1306097", "url": "https://alliancegenome.org/gene/RGD:1306097#orthology", "database": "AGR" }, { "id": "SGD:S000002548", "url": "https://alliancegenome.org/gene/SGD:S000002548#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q03921-1", "protein_name": "Protein DOP1", "gene_name": "DOP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSLPLKPLTIDSNNKQLDSKQKKFRANVERALERFDSVTEWADYIASLGTLLKALQSWSPKFQNVRYYVPSPYQVSRRLTSSLSPALPAGVHQKTLEVYTYIFEHIGLETLATECNIWIPGILPLMTYASMSVRSHLIELYDNYILLLPQTTLRLLIRPLISSLLPGIDDESNDFLPLTLKLIETLQENLDDDSLFWQTLFLVMTANKGRRLGGLTWLTRKFPSLNAVPHLVNKIKMEAEENPSETETNDSHLDRKKRKEEAFKVLLPAAKDLVTPEPGLLIRCLVGCLEDENDILIKRSVLDLLLQRLRLDSPVLNVLITSEDKKLLIMSCCRTTLSKDMSLNRRIWNWLLGPTAGGMLNNNGGNSMEYTTSVKSANEESNVYFTKYGLSALLEGLSDLLSEEESVLTAFRISMAVMDRWEIGSLVIPELFIPLLYSSEKFKQNEQIMKTARTFFDNTETNIIWGKLFQELEDIKNLKILDFVLTNFNIGNDEEIIVRHLPLILLTLLALPSNDKDFDNIYKLQKFSLYNKLLNYIPERALLPLSHSKLKHDDEVSCEELLAKIRGFYTNVSNPSSILEKENIAERLPPFTTEDLTFLIADLIQKKLLSSLWDLENINESSKLFIAIFEKIPESEELKGRSHISWSDKKITQSIFEAIPRLCESNNDAKSEEIVGIVEIFGNYLYSRMEFIESMKLLKVVMMAVWKSLKDPRHQILGVKNLKTLNRFIPSKFIESALVYTFVEEEDISERLSVLDLLWTQLDSDSNLIRRPLELILGELFDDQNPFYLTVSKWILSILNSGSASRLFYILTDNILKVNRLEKERLDERDDLDMLTYEFQMLAYVLKTNNGRTRKVFSTELTSIKSSTIWKNEDVSTYKSLLLVTLMRFLNIKSNTHAKSIRSALILLDILLDGTEQNFKDIVIFLLQMSSKYIAEEGIEPELIAVSLLDIVSKVLRLSHDNGIKLDIFDDNAAHLKYIDFLVTSVSNMKSPLIVTAYVKLLSESIVYFENSIFRMILPLSASLVQCVQRLFLLEKREGGYYQPIALLLGGLEELLEISHGYLVTEEREGYFSGSNLKGDFIQSVVSNVFSSDSSNEESKIQGERDVILQSFRQVISCCLDIWYWAHNISCKSNDDSSLDATNHNSYKFKFRSKKLLETLFLLEPLELLENLISIRSDNTTVTLVHVLDGNKPAITIPHLLYGVIIRYNRTASVKFSNRDGSRSSTTKLTKGEPSMLKRLSGESIIAFLFNYVDSVENSAMEEFYGDFLLFFREVATNYNLYSDVSLSILKLVALISGKVSKTQFGEQKRVRREISDVFFKYLPNAFINFTNLYRGHPDSFKDLEFVVWRVQYIVNDQIGGDKFNTTLATIVNQCLTPYIKPKSEKTIPGYVLELAAVVSHLGSKVKSWRLLIAELFQNDKKLSVIGSDQTWEKIIYEWSIYPENKSKILNDLLLEIGSKRSSVTPTLITFNLGSDSEVEYKCQNLLKISYLLMVSPNDAYLLHFSSLISCIFHYLVSKDIKLKGSCWILLRVLLLRFSESHFNDYWSMISYCLQTNLQEFYESLQIQSEVDPQTILQVCKTLDLLLLLNMEGFTSTNEWIFVIDTINCVYKTNSFVALVDEIAEFKDYEITKTDDLELPTTLKDGLPLLRGIHKIERHTQLRSFFQNLSYLHYEKVYGLGSVDLYGCGEDLKKDILS", "length": 1698 }, "evidence": [ { "id": "MGI:1917278", "url": "https://alliancegenome.org/gene/MGI:1917278#orthology", "database": "AGR" }, { "id": "HGNC:1291", "url": "https://alliancegenome.org/gene/HGNC:1291#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1195", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1195#orthology", "database": "AGR" }, { "id": "FB:FBgn0034400", "url": "https://alliancegenome.org/gene/FB:FBgn0034400#orthology", "database": "AGR" }, { "id": "RGD:1306097", "url": "https://alliancegenome.org/gene/RGD:1306097#orthology", "database": "AGR" }, { "id": "SGD:S000002548", "url": "https://alliancegenome.org/gene/SGD:S000002548#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3UHQ6-1", "protein_name": "Protein DOP1B", "gene_name": "Dop1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSNLKYSLLPRRLIISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAYAAMSVRPVLLGLYEKYFLPLQKLLLPSLQAFLVGLLPGLEEGSEIYERTDALLLRLSVVVGREVFYAALWGSVLTSPSIRLPASLFVVNHISRDSPGKEQKCMLGTDYQLTVRSLCASLLDANVLVQRNNLEIILFFFPFYTCLDPEERAIPLLRRDVVHILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTIVPKSEISNSYEDQCSYFFDKYSKDLLVEALAEILHQKFLDADLEERHHAYLKPFRILVSLLDKPEIGPQVVENLFLEVIRAFYSYCHDVLGSDLKLSYTQSGNPLISTIKENRHASEIVKTVNLLVSSLSSDFLWDYMARRFEACFRPVTQTTAIGEAISPPPTVSELCTLLVFLLDVIPLELYSEVQTQYLPQVLGCLLQPLAEEVEALSLPELTHALKTCFKVLSKVQMPPSYLDLEPSSGNSSPVKGRNSGIAMETEAVVAGDEEPSFPPLKSEDSGIGLSASSPELSEHLRVPRVSAERDDIWKKDGTMQATFLCIQELIANFASKNIFAASLTVSGEENKPEEPPGKGNKGQTQSTEHPGRKSSWDPKPITVPQFKQMLSDLFTVRGSPFKTRSSESLSSVPSSPHRKAATEWGVDQVVVELVGSKEDCREALAAACHLLLDCATFPVYLSEEETEQLCETLFQTPGASDCSFPPWLKSLMTICCCVSDCSLQNIAIATLLEVINHSQSLALVIEDKMKRYKTSGNNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHITCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTREIQGSRVTSHNRSFDRSLFVVLDSLACTDGAISAAAQGWLVRALSLGDVARILEPMLLLLLQPKTQRTSIQCLKQENSAEDLHRWFNRKKPTCKEACGESEPQEGAPEERLPRGQFTTVDREAIWAEVEKEPEKCPPRSDLSEEDLPYYVDLPDRMTSGGGDSSEHTESADTSSGHTDSENTSTFSSPSHDLQDLSHEENCCAPIPIGGRAYSKRAALLAAFQPESPRSNARLSLVRADSDKTQASESFSSDEEADVELQAITTSRLLKQQREKQETVEALFKHILLYLQPYDSQRVLYAFSVLEAVLKTNPKEFIEAVSRTGIDTSSTAHLNLISNLLARHQEALIGQSFYGKLQTQAPNVCPHSLLIELLTYLCLSFLRSYYPCYLKVCHRDILGNRDVQVKSVEVLIRITAQLVSMAKSAEGKNTEFIHSLLQRCKVQEFVLLSLSASMYTSQKRYGLATADRGGRLLAEDSLFEESLINLGQDQIWSEHPLQIELLKLLQALIVLEHHLGQGQEEAETQPALSREWQRALNFQQAIGAMQYVQPHPLTSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVIQICKNLDDLVKQYESESVKFTISTTSKKENISPDYPLTLLEGLTTISHFCLLEQPTQHKKTAAVSDPINLRNAKNAILEELPRIVNTMALIWNVLRKEETQKRPVDLLGATKGSSSVYFKTTKTIRQKILDLLNPLTGHLGVQLIAAVATVWNRKQARRHSKTKMVPVANTSQHTLVDLVCALSTLQTDSVLQLVKEVVKRPAQIKGDEKSPLVDIPVLQFCYAFIQRLSIPDLQEAFPSLLGVLKEAAQLNLAPPGYFLLLSMLNDFVTRTPNLESKKDQKDLQEITQRILEAVGTIAGSSLEQTSWLSRNLEVKAQPQVSLEESDAEDDVHSAAEASTMVSASAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWKKEVLELFLDPAFFQMDTSCVHWKSVIDHLLTHEKTMFKDLMNMQSSSLKLFSSFEQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSIVAGQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFIQLEEDLKEEDESRNSHKSNRIKAPVADGNGSAGRVLSPSDLTMYLSACKFLDTALAFPPDKMPLFQIYRWAFVPEVDTEHPAFLSELEENHQECRPHTVRILELLRSRYGEIGSSDEITRKKEFPLLRQHSVSCIRQLIPFFTTLNCAFKTQSQLPADVPGTAAPECPVTENPRVLRQLEECVEQDFLEHPEC", "length": 2295 }, "evidence": [ { "id": "MGI:1917278", "url": "https://alliancegenome.org/gene/MGI:1917278#orthology", "database": "AGR" }, { "id": "HGNC:1291", "url": "https://alliancegenome.org/gene/HGNC:1291#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1195", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1195#orthology", "database": "AGR" }, { "id": "FB:FBgn0034400", "url": "https://alliancegenome.org/gene/FB:FBgn0034400#orthology", "database": "AGR" }, { "id": "RGD:1306097", "url": "https://alliancegenome.org/gene/RGD:1306097#orthology", "database": "AGR" }, { "id": "SGD:S000002548", "url": "https://alliancegenome.org/gene/SGD:S000002548#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5JWR5-1", "protein_name": "Protein DOP1A", "gene_name": "DOP1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPTLLSLYEIYYLPLGKTLKPGLQGLLTGILPGLEEGSEYYERTNMLLEKVAAAVDQSAFYSALWGSLLTSPAVRLPGITYVLAHLNRKLSMEDQLYIIGSDIELMVEAVSTSVQDSSVLVQRSTLDLILFCFPFHMSQATRPDMIRILSAALHVVLRRDMSLNRRLYAWLLGFDNNGAIIGPRSTRHSNPEEHATYYFTTFSKELLVQAMVGILQVNGFGEENTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQTEPPFSKDHAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYVARWFEECCRRTLHVRLQIGPGDSNDSSELQLTNFCLLVDFLLDIVSLPTRSMRVLCQETYIEIQTEHLPQLLLRMISALTSHLQTLHLSELTDSLRLCSKILSKVQPPLLSASTGGVLQFPSGQNNSVKEWEDKKVSSVSHENPTEVFEDGENPPSSRSSESGFTEFIQYQADRTDDIDRELSEGQGAAAIPIGSTSSETETASTVGSEETIIQTPSVVTQGTATRSRKTAQKTAMQCCLEYVQQFLTRLINLYIIQNNSFSQSLATEHQGDLGREQGETSKWDRNSQGDVKEKNISKQKTSKEYLSAFLAACQLFLECSSFPVYIAEGNHTSELRSEKLETDCEHVQPPQWLQTLMNACSQASDFSVQSVAISLVMDLVGLTQSVAMVTGENINSVEPAQPLSPNQGRVAVVIRPPLTQGNLRYIAEKTEFFKHVALTLWDQLGDGTPQHHQKSVELFYQLHNLVPSSSICEDVISQQLTHKDKKIRMEAHAKFAVLWHLTRDLHINKSSSFVRSFDRSLFIMLDSLNSLDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWNKSPCYPGEESDKHFMQNFACSNVSQVQLITSKGNGEKPLTMDEIENFSLTVNPLSDRLSLLSTSSETIPMVVSDFDLPDQQIEILQSSDSGCSQSSAGDNLSYEVDPETVNAQEDSQMPKESSPDDDVQQVVFDLICKVVSGLEVESASVTSQLEIEAMPPKCSDIDPDEETIKIEDDSIQQSQNALLSNESSQFLSVSAEGGHECVANGISRNSSSPCISGTTHTLHDSSVASIETKSRQRSHSSIQFSFKEKLSEKVSEKETIVKESGKQPGAKPKVKLARKKDDDKKKSSNEKLKQTSVFFSDGLDLENWYSCGEGDISEIESDMGSPGSRKSPNFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKAILKTNPIAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIPVDSNHNFRSSMYIEILISLCLYYMRSHYPTHVKVTAQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFPSFISDMLSKCKVQKVILHCLLSSIFSAQKWHSEKMAGKNLVAVEEGFSEDSLINFSEDEFDNGSTLQSQLLKVLQRLIVLEHRVMTIPEENETGFDFVVSDLEHISPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGKVLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWMASIIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVSVDQKHLFEARSGILSILHMIMSSVTLLWSILHQADSSEKMTIAASASLTTINLGATKNLRQQILELLGPISMNHGVHFMAAIAFVWNERRQNKTTTRTKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAKDKKHLSLEVCMLQFFYAYIQRIPVPNLVDSWASLLILLKDSIQLSLPAPGQFLILGVLNEFIMKNPSLENKKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETANITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDASCVNHWRAIMDNLMTHDKTTFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAIFSSEIDQYQKYLPDIQERLVESLRLPQVPTLHSQVFLFFRVLLLRMSPQHLTSLWPTMITELVQVFLLMEQELTADEDISRTSGPSVAGLETTYTGGNGFSTSYNSQRWLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSGLEVRRQGIHQREFKPYVVRLAKLLRKRAKKNPEEDNSGRTLGWEPGHLLLTICTVRSMEQLLPFFNVLSQVFNSKVTSRCGGHSGSPILYSNAFPNKDMKLENHKPCSSKARQKIEEMVEKDFLEGMIKT", "length": 2465 }, "evidence": [ { "id": "FB:FBgn0034400", "url": "https://alliancegenome.org/gene/FB:FBgn0034400#orthology", "database": "AGR" }, { "id": "SGD:S000002548", "url": "https://alliancegenome.org/gene/SGD:S000002548#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BL99-1", "protein_name": "Protein DOP1A", "gene_name": "Dop1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTEELELLSDSKYRNYVAAIDKALKNFEYSSEWADLISALGKLNKVLQNNAKYQVVPKKLTIGKRLAQCLHPALPGGVHRKALETYEIIFKIIGPKRLAKDLFLYSSGLFPLLANAAMSVKPALLGLYEMYYLPLGKTLKPGLQGLLTGILPGLEEGSEYYERTNTLLEKVAAAVEQSAFYSALWGSLLTSPAVRLPGITYVLAHLNRKLSMEDQLYIIGSDIELMVEAVSTSVQDSSVLVQRSTLDLILFCFPFHMSQATRPDMIRILSAALHVVLRRDMSLNRRLYAWLLGFDNNGAIIGPRSTRHSNPEEHATYYFTTFSKELLVQAMVGILQVNGFGEESTLMQDLKPFRILISLLDKPELGPVILEDVLIEVFRTLYSQCKAELDLQMEPPFSKDHAQLSSKLRENKKTAELIKTANLLFNSFEPYYMWDYIARWFEECCRQSFFLSRRTLHARLQVGPGDSSDSSELQLTNFCLLVDFLLDIVSLETYIEIQTEHLPQLLLRMISALTSHLQTLRLSELTDSLRLCSKILSKVQPPLLSAGNGGVVQFPSGQNSTVKEWEDKKQVSSVSMENPAEVFEDGENPPSSRSSESGFTEFIQYQADRPDDLDRELNGQGAATIPIGSTSSETETASTVGSEETVIQPPSTFTQGAAGRSGKAVQKTAMQCCLEYVQQFLSRLINLYIIHSDSFPQALAADHQGDFSRIQRETSKWDRDSQGDAKERNIHTPKTSKEYLSAFLAACQLFLECSSFPVYIAEGNHTSESHSEKPDTDCEHAHPPQWLRTLMSACSQARDFRVQSAAVSLVMDLVGLTQSVAMVTGENINSMEPAQPLSPNQGRVAVVIRPPLTQGNLKYIAEKTEFFKHVALTLWDQLGDGTPQHHQKSVELFYQLHNLVPSSSICEDVVSQQLTHKDKKIRMEAHAKFAVLWHLTRDLHINKSSFARSFDRSLFIMLDSLTSLDGSTSSVGQAWLNQVLQRHDIARVLEPLLLLLLHPKTQRVSVQRVQAERYWSKTSCYPGEENDKHFMQNFTCNNVSQVHLIASKGNGEKPLTMDEMENFSLTVNPLSDRLSLLSTSSETIPMVVSDFDLPDQQMEILQSSDSGCSQSSAGDNFSYEVDPENANAHEDSHMAKASSPDDDVQQVVFDLICKVVSGLEAESESVTSELEIESLQTKSSDLDPGKEATKIEDQAPQHSQHVLLSDDSPRFLSVSTEEGCECLANGISRNSSSPCISGTAQTLNDSSVPSETKSRQRSHSSIQFSFKEKLSEKVSEKETIVKESGKQPGAKPKVKLARKKDEDKKKAASEKLKQANVFFSEGLDLENWYSCGEGEISEIESDMGSPGSRKSPNFNIHPLYQHVLLYLQLYDSSRTLYAFSAIKSILKTNPIAFVNAISTTSVNNAYTPQLSLLQNLLARHRISVMGKDFYSHIPVDSNHNFRSSMYIEILISLCLYYMRSHYPTHVKVTTQDLIGNRNMQMMSIEILTLLFTELAKVIESSAKGFPSFISDMLSKCKVQKVILHCLLSSIFSVQKWHSEKTAGKSMVAVEEGFSEDSLINFSEDELDNGSTLQSQLLRVLQRLIVLEHHVMTIPEENEAGFDFVVSDLEHISPHQPMTSLQYLHAQPITCQGMFLCAVIRALHQHCACKMHPQWIGLITSTLPYMGKVLQRVVVSVTLQLCRNLDNLIQQYKYETGLSDSRPLWVASIIPPDMILTLLEGITAIIHYCLLDPTTQYHQLLVNVDQKHLVEARSGILSILHMIMSSVTLLWSILHQADASEKMAVAASASVTTINLGATKVIPAASEEQLLLVELVRSISVMRAETVIQTVKEVLKQPPAIAKDKVRKLCFCRKFSFRTGADRIPVPNIVDSWTSLLVLLKDSIQLSLPAPGQFLILGVLNEFIMKNPSLENKKDQRDLQDVTHKIVDAIGAIAGSSLEQTTWLRRNLEVKPSPKIMVDGTNLESDVEDMLSPAMETSNITPSVYSVHALTLLSEVLAHLLDMVFYSDEKERVIPLLVNIMHYVVPYLRNHSAHNAPSYRACVQLLSSLSGYQYTRRAWKKEAFDLFMDPSFFQMDASCVSHWRAIMDNLMTHDKTTFRDLMTRVAVAQSSSLNLFANRDVELEQRAMLLKRLAFAVLSSESDQYQKYLPDIQERLVESLRLPQVQVFLLMEQELTADEDISRTSGPSAAGLETTYTGGNGFSTSYNSQRWLNLYLSACKFLDLALALPSENLPQFQMYRWAFIPEASDDSGLEVRRQGIHQREFKPYVVRLAKLLRKRAKDEEDFKILEGLEMAKHQKNPEEDCSGRTLGWEPGHLLLTLCTMRNMEQLLPFFNVLSQVFNSKVTSRCGGHSGSPVLYPNSFPNKDMKLENHKAFSSKARQKIEEMIEKDFLEGVIKT", "length": 2399 }, "evidence": [ { "id": "FB:FBgn0034400", "url": "https://alliancegenome.org/gene/FB:FBgn0034400#orthology", "database": "AGR" }, { "id": "SGD:S000002548", "url": "https://alliancegenome.org/gene/SGD:S000002548#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3R5-1", "protein_name": "Protein DOP1B", "gene_name": "DOP1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISSLGKLNKALQSNLRYSLLPRRLLISKRLAQCLHPALPSGVHLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAHAAVSVRPVLLTLYEKYFLPLQKLLLPSLQAFIVGLLPGLEEGSEISDRTDALLLRLSLVVGKEVFYTALWGSVLASPSIRLPASVFVVGHINRDAPGREQKYMLGTNHQLTVKSLRASLLDSNVLVQRNNLEIVLFFFPFYTCLDSNERAIPLLRSDIVRILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTVVPESEISNSYEDQSSYFFEKYSKDLLVEGLAEILHQKFIDADVEERHHAYLKPFRVLISLLDKPEIGPQVVGNLFLEVIRAFYSYCRDALGSDLKLSYTQSGNSLISAIKENRNASEIVKTVNLLITSLSTDFLWDYMTRCFEECFRPVKQRYSVRNSVSPPPTVSELCALLVFLLDVIPLELYSEVQTQYLPQVLGCLVQPLAEDMEALSLPELTHALKTCFKVLSKVQMPPSYLDTESTSGTSSPVKGENGKIILETKAVIPGDEDASFPPLKSEDSGIGLSASSPELSEHLRVPRVSLERDDVWKKGGSMQRTFLCIQELIANFASKNIFGVQLTASGEESKSEEPAGKRDRDGTQSLAANDSSRKNSWEPKPITVPQFKQMLSDLFTARGSPFKTKSSESPSSSPSSPARKNGGEWDVEKVVIDLGGSREERREAFAAACHLLLDCATFPVYLSEEETEQLCATLFQLPGAGDSSFPSWLKSLMTICCCVTDCYLQNVAISTLLEVINHSQSLALVIEDKMKRYKSSGHNPFFGKLQMVTVPPIAPGILKVIAEKTDFYQRVARVLWNQLNKETREHHVTCVELFYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSVIWHLTREIQGSRVTSHNRSFDRSLFVVLDSLACTDGAIGAAAQGWLVRALSLGDVARILEPVLLLLLQPKTQRTSIHCLKQENSADDLHRWFNRKKTSFREACAVPEPQESGSEEHLPLSQFTTVDREAIWAEVEKEPEKYPLRGELSEEELPYYVELPDRTAHGAPDSSEHTESADTSSCHTDSENTSSFSSPSHDLQELSNEENCCAPIPMGGRAYPKRSALLAAFQSESFKAGAKLSLVRVDSDKTQASESFSSDEEADLELQALTTSRLLKQQRERQEAVEALFKHILLYLQPYDSRRVLYAFSVLEAVLKTNPKEFIEAVSRTSMDTSSTAHLNLISNLLARHQEALIGQSFYGKLQTQVPNVCPHSLLLELLTYLCLSFLRSYYPCYLKVSHRDILGNRDVQVKSVEVLIRIMMQLVSVAKSSEGKNVEFIHSLLQRCKVQEFVLLSLSASMYTSQKRYGLATAHHGRALPEDSLFEESLINLGQDQIWSEHPLQIELLKLLQVLIVLEHHLGRAHEEAENQPDLSREWQRALNFQQAISALQYVQPHPLTSQGLLVSAVVRGLQPAYGYGMHPAWVSLVTHSLPYFGKSLGWTVTPFVVQICKNLDDLVKQYESESVKLSVSTTSKRENISPDYPLTLLEGLTTISHFCLLEQANQNKKTMAAGDPANLRNARNAILEELPRTVNTMALLWNVLRKEETQKRPVDLLGATKGSSSVYFKTTKTIRQKILDFLNPLTAHLGVQLTAAVAAVWSRKKAQRHSKMKIIPTASASQLTLVDLVCALSTLQTDTLLHLVKEVVKRPPQVKGGDEKSPLVDIPVLQFCYAFLQRLPVPALQENFSSLLGVLKESVQLNLAPPGYFLLLSMLNDFVTRTPNLENKKDQKDLQEITQKILEAVGNIAGSSLEQTSWLSRNLEVKAQPQASLEESDAEEDLYDAAAASAMVSSSAPSVYSVQALSLLAEVLASLLDMVYRSDEKEKAVPLISRLLYYVFPYLRNHSAYNAPSFRAGAQLLSSLSGYAYTKRAWRKEVLELFLDPAFFQMDTSCVHWKSIIDHLLTHEKTMFKDLMNMQSSSLKLFSSFEQKAMLLKRQAFAVFSGELDQYHLYLPLIQERLTDNLRVGQTSIVAAQMFLFFRVLLLRISPQHLTSLWPIMVSELIQTFTQLEEDLKDEDESLRSTNKVNRTKVSVPDANGPSVGEIPQSELILYLSACKFLDTALSFPPDKMPLFQIYRWAFIPEVDTEGPAFLSDVEENHQECKPHTVRILELLKLKFGEISSSDEITMKSEFPLLRQHSVSSIRQLMPFFMTLNGAFKTQRQLPADSPGTPFLDFPVTDSPRILKQLEECIEYDFLEHPEC", "length": 2298 }, "evidence": [ { "id": "MGI:1917278", "url": "https://alliancegenome.org/gene/MGI:1917278#orthology", "database": "AGR" }, { "id": "HGNC:1291", "url": "https://alliancegenome.org/gene/HGNC:1291#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1195", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1195#orthology", "database": "AGR" }, { "id": "FB:FBgn0034400", "url": "https://alliancegenome.org/gene/FB:FBgn0034400#orthology", "database": "AGR" }, { "id": "RGD:1306097", "url": "https://alliancegenome.org/gene/RGD:1306097#orthology", "database": "AGR" }, { "id": "SGD:S000002548", "url": "https://alliancegenome.org/gene/SGD:S000002548#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8M9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9" } ], "pmid": "" }, { "name": "endosome", "id": "GO:0005768", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005768", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8M9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8M9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9" } ], "pmid": "" }, { "name": "trans-Golgi network", "id": "GO:0005802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005802", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8M9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8M9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9" } ], "pmid": "" }, { "name": "Golgi to endosome transport", "id": "GO:0006895", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006895", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8M9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1038, "end_pos": 1040, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1136, "end_pos": 1138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1140, "end_pos": 1142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1287, "end_pos": 1289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1593, "end_pos": 1595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1638, "end_pos": 1640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1960, "end_pos": 1962, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2233, "end_pos": 2235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2272, "end_pos": 2274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 405, "end_pos": 407, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 630, "end_pos": 632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 654, "end_pos": 656, "annotation": "n_glycosylation_sequon" }, { "start_pos": 692, "end_pos": 694, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" }, { "start_pos": 841, "end_pos": 843, "annotation": "n_glycosylation_sequon" }, { "start_pos": 973, "end_pos": 975, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z8M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9" }, { "id": "PF04118", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04118" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOP1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 303, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z8M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9" }, { "id": "PF24598", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24598" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOP1-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 1786, "end_pos": 2267, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z8M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9" }, { "id": "PF24601", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24601" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOP1-like TPR", "eco_id": "ECO_0000259", "start_pos": 1210, "end_pos": 1623, "start_aa": "Ser", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M6Z8M9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8M9" }, { "id": "PF24597", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24597" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOP1-like middle TPR", "eco_id": "ECO_0000259", "start_pos": 327, "end_pos": 562, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1295 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1038, "end_pos": 1040 }, { "start_pos": 1136, "end_pos": 1138 }, { "start_pos": 1140, "end_pos": 1142 }, { "start_pos": 1287, "end_pos": 1289 }, { "start_pos": 1593, "end_pos": 1595 }, { "start_pos": 1638, "end_pos": 1640 }, { "start_pos": 1960, "end_pos": 1962 }, { "start_pos": 2233, "end_pos": 2235 }, { "start_pos": 2272, "end_pos": 2274 }, { "start_pos": 404, "end_pos": 406 }, { "start_pos": 405, "end_pos": 407 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 630, "end_pos": 632 }, { "start_pos": 654, "end_pos": 656 }, { "start_pos": 692, "end_pos": 694 }, { "start_pos": 801, "end_pos": 803 }, { "start_pos": 841, "end_pos": 843 }, { "start_pos": 973, "end_pos": 975 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z8N3-1", "uniprot_ac": "A0A8M6Z8N3", "uniprot_id": "A0A8M6Z8N3_DANRE", "mass": { "chemical_mass": 218335.0, "monoisotopic_mass": 218335.0 }, "refseq": { "ac": "XP_017213328", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213328" }, "gene_names": [ { "name": "LOC108191338", "type": "recommended", "evidence": [ { "id": "A0A8M6Z8N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8N3" } ] }, { "name": "LOC108191338", "type": "synonym", "evidence": [ { "id": "XP_017213328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213328" } ] } ], "protein_names": [ { "name": "Integrase catalytic domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M6Z8N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8N3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017213328", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213328" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017213328.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213328", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213328" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8N3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8N3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108191338", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8N3", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z8N3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z8N3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01644", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01644", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "108191338", "url": "https://www.ncbi.nlm.nih.gov/gene/108191338", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108191338", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191338", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z8N3", "url": "https://www.orthodb.org/?gene=A0A8M6Z8N3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47331:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47331:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213328", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213328", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8N3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8N3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8N3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTTETSSLKTRSCASCSSARSNTSSTGSAAAKARARAEAAKARLTFAEEEVNLKLQKAKVEASMEMLQQKKEVAAAVAEAEALEAAIDEHSEKHSCKLSLNSVPLETTQRTEQYVIDQTKNLDKDLQLCDVPAKIEPSTSYSISGSQLKPEAKPFLLRHNSVSFQLPDTTLKHSATSPANKYPTPSQQFGSQNSINTSNPLNSEYPMFQNSNDCSSNMNDFVRYLARRELVSTGLLQFNDKPQNYRAWKRSFQNATFDLNLTPSEEMDLLLKWLGKESAEQVEQIRAIHINHPQAGLAMAWDRLDQTYGSAEIIEHALFKRIDAFPKIANRDYSKLSKLSDLLMELQSAKAEGDLPGLVLLDTARGIYPIIQKLPFRLQEKWASVGAAYKRHNQVPYPPFAYFVDFVSQEADIGNDPSFSFVSYIDTAPKVEKAAWKSSKQHEIFVHKTAVSYGDCADTGGLYKQSDDCDKLCLIHKRPHPLNKCRVLLEKSTDARKAFLREHNVCFKCCSSTTHIAKNCKTKVQCSECKSEGHNTVLHPGHASWKESNPATKHGGEGEQPLSQSQVDSKCTEVCGENQTDRSCSKVCLVKVFPAGQKDKAVKVYAILDEQSNRSLVRSPFFEVFSDQSPCAPYILRTCAGVKESAGRRASGYEVESLDGTVCISLPSLIECNDIPNNRDEIPTPDVARSHTHLKSMAHFIPELDPKAPIMLLLGRDVIRVHKVRKQVNGPHNLPYAQKLDLGWVIVGNVCLGNVHKPLTISTFHTNTIEPERPTLFKPCPNVFHVKETCKDFQIANHCPTYPEAKFTCDVDCLGDNVFQRTKEDNQVAPSIQDATFMKIMDEGLRKDSNNSWVAPLPFKSPRPRLPNNRIQALKRLISLKHNFERKPMMKEHFLKFMEKIFKNGHAELAPPLDEKEEQWYLPIFGVYHPKKVNQIRVVFDSSAQHNAISLNDVLLTGPDLNNTLVGVMMRFRKEAIAFTADIEQMFYCFLVREEDRDFLRFLWFQDNDTSKDIVDYRMRVHVFGNKPSPAVAIHCLHKSVQIDNFHVDSEVKQFVMRDFYVDDGLKSLPTVEATISLLKKTQEVLSKSNLRLHKIAANSKKVMEAFPSTDHACDLKDLDFEEDTLPMQRSLGLNWDLHSDCFRFSVSDEVKPYTRRGVLSTINRLYDPLGFVAPVTIQGKAILRELTAVSGDWDAPLPQKMEDAWTLWRVSLSELANFSIPRVYTEISTSTTMRRELCVFADASIKAIAAVSYLKVTDDEGKNHIGFVMGKAKLAPRPEQTVPRLELCAAVLAVELADLISVNLDLQFDAVTYYTDSKVVLGYICNETRRFYVYVSNRVQRIRRSSSPDQWRYVPTEQNPADHATRFVSAAHLQKTNWLSGPNFLLTQGPDIQNTFNLVNPSSDPDVRPLVSTLTTTALTKQLGSERFAKFSSWNSLTGAITRLIHIAHHFKTTEKENSSCKGWHYCKEFTMEESDRAINIILRAVQEEAYSHEIECIKRQERIPKSSPLHTLDPFIDQQGLLRVGGRLHLSSLNQREKTPLLIPGKSHIATLIIRHHHERVQHQGRHFTEGAVRAAGFWIIGGKRRVCSIIHQCVTCRRLRAPLSIQKMANLPAERLSADPPFTNVGLDVFGPWNVSSRRTRGGLLYSKRWAVIFTCMSIRAVHIEVIESLDTSSFINALRRFLAVRGPVKHIRSDRGTNFVGACKELQIPSNIDSKVVKTYLSDQGCTWTFNPPHASHCGGSWERMIGLARRILDSMFLQLTDKLTHEVLVTFMAEVTAIINARPLVPVTTDPHESFILTPAALLTQKVNPVAAPTGEFGVTDLYKCQWRQVQHLSNTFWDRWRKQFLPTLQPRRKWQSVHPNVNTGSVVLLKNSQVPRNEWPLGLVTQSFPSKDGKVRQVEVKVIKPGGSTLFLRPVTEVVLLLSSESKVDE", "length": 1936, "header": "tr|A0A8M6Z8N3-1|A0A8M6Z8N3_DANRE Isoform 1 of Integrase catalytic domain-containing protein OS=Danio rerio OX=7955 GN=LOC108191338 PE=4 SV=2 CANONICAL=A0A8M6Z8N3-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z8N3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8N3/entry#A0A8M6Z8N3-1", "sequence": { "sequence": 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"length": 1936, "header": "tr|A0A8M6Z8N3-1|A0A8M6Z8N3_DANRE Isoform 1 of Integrase catalytic domain-containing protein OS=Danio rerio OX=7955 GN=LOC108191338 PE=4 SV=2 CANONICAL=A0A8M6Z8N3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 184, "start_aa": "Thr", "end_pos": 184, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr184", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:108191338", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191338", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8N3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8N3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8N3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8N3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1008, "end_pos": 1010, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1218, "end_pos": 1220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1327, "end_pos": 1329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1459, "end_pos": 1461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1637, "end_pos": 1639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 613, "end_pos": 615, "annotation": "n_glycosylation_sequon" }, { "start_pos": 850, "end_pos": 852, "annotation": "n_glycosylation_sequon" }, { "start_pos": 962, "end_pos": 964, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z8N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8N3" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 1619, "end_pos": 1812, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 184 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1008, "end_pos": 1010 }, { "start_pos": 1218, "end_pos": 1220 }, { "start_pos": 1327, "end_pos": 1329 }, { "start_pos": 1459, "end_pos": 1461 }, { "start_pos": 1637, "end_pos": 1639 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 22, "end_pos": 24 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 578, "end_pos": 580 }, { "start_pos": 613, "end_pos": 615 }, { "start_pos": 850, "end_pos": 852 }, { "start_pos": 962, "end_pos": 964 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z8X3-1", "uniprot_ac": "A0A8M6Z8X3", "uniprot_id": "A0A8M6Z8X3_DANRE", "mass": { "chemical_mass": 38349.0, "monoisotopic_mass": 38349.0 }, "refseq": { "ac": "XP_017213583", "name": "trace amine-associated receptor 13c-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213583" }, "gene_names": [ { "name": "si:ch211-238p8.31", "type": "recommended", "evidence": [ { "id": "A0A8M6Z8X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X3" } ] }, { "name": "si:ch211-238p8.31", "type": "synonym", "evidence": [ { "id": "XP_017213583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213583" } ] } ], "protein_names": [ { "name": "Trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "A0A8M6Z8X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X3/entry#names_and_taxonomy" } ] }, { "name": "trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "XP_017213583", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213583" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213583" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-238p8.31", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091113-50", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-50", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z8X3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z8X3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "108191511", "url": "https://www.ncbi.nlm.nih.gov/gene/108191511", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108191511", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191511", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z8X3", "url": "https://www.orthodb.org/?gene=A0A8M6Z8X3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249:SF381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249:SF381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213583", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213583", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091113-50", "url": "https://zfin.org/ZDB-GENE-091113-50", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKEKRSSHEYNIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVTDMFVGLIVIPVKAIKLIERCWYFGDTFCGLFIIIIGVIFSASLSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMSICLSWLYYSAYNTALIINNGYFDTSNRTDMCNGECPVMVSFSWILTDLSMCFIFPCLIMITLYSRIFFAVHQQVKVINSLMKRDKCVMKGSVKRKSERKAALTLGIIVTIYLLCYIPYYICSLVIISSTALNVLTWTMYANSGLNPLVYALFYPWFKKTAKLILTLKIFQPASSLVNIFTENEL", "length": 335, "header": "tr|A0A8M6Z8X3-1|A0A8M6Z8X3_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=si:ch211-238p8.31 PE=3 SV=1 CANONICAL=A0A8M6Z8X3-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z8X3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X3/entry#A0A8M6Z8X3-1", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKEKRSSHEYNIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVTDMFVGLIVIPVKAIKLIERCWYFGDTFCGLFIIIIGVIFSASLSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMSICLSWLYYSAYNTALIINNGYFDTSNRTDMCNGECPVMVSFSWILTDLSMCFIFPCLIMITLYSRIFFAVHQQVKVINSLMKRDKCVMKGSVKRKSERKAALTLGIIVTIYLLCYIPYYICSLVIISSTALNVLTWTMYANSGLNPLVYALFYPWFKKTAKLILTLKIFQPASSLVNIFTENEL", "length": 335, "header": "tr|A0A8M6Z8X3-1|A0A8M6Z8X3_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=si:ch211-238p8.31 PE=3 SV=1 CANONICAL=A0A8M6Z8X3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108191511", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191511", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NV51-1", "protein_name": "Trace amine associated receptor 19p", "gene_name": "taar19p", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEHQDTQYCFPNINSSCVKGKRSIQEYNIMYVLFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVTDLLIGLIVMPIQAIRLIETCWYFGDTLCGINLIIIGVIFSASFSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMCICLSWVYYSAYNTGLVINNGYFDTSHRTDVCYGDCSVIMSFSWLVTDLCLSFIFPCVIMITLYLRIFYVVHQQVKVINSLMKGGKCVTKGSVKRKSESKAALTLGIIVLVYLLCYIPYYICTLSVNSSTTITVLEWTVYTNSGLNPLVYALFYHWFKKTVKLILTLKIFHPESSLINVFTVHEL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z0V5-1", "protein_name": "Trace amine-associated receptor 13c", "gene_name": "taar19t", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDADTVYIKGQKGEQNKLLTGGDSLMAYETEDQETQYCFPDINSSCVKEKRSIQEYNIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLILMPVEAIRLIETCWYFGETFCVLYLILIGLIFSATLSCLVLIAVDRYVAVCHPLLYPQKITITNMLMSICLSWVCYSAYNTAFAFNNGYLNSSHRRDVCYGQCFIMMTFSWTVTDLSMCFIFPCVIMITLYSRIFYVVHQQVKVINSLMKGGKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTITVLMWTVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 361 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z0W1-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19h", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDYETEDQETQYCFPDINSSCVKYQRSSHEYNIMYVFFYFLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLVGLIVMPIQAIRLIETCWYFGDTFCGISLILSGVIISASLTNLVLIAVDRYVAVCHPLLYPQKITITNMLLIICLSWIYYSGYNTVLIIYNGYFETSERTDACDGDCLVMIRFSWIVTDLFISFIFPCVIIITLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVKRKSESKAALTLGIIVSVYLLSWIPYCICSVTVNSSTLITILSWTVYTNSGLNPLVYAIFYPWFKKTVKVILTLKIFDPASSLVNIFMEHDL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1I0-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKGRHSSHGYIIIYLFVSLLSVWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLIIGLFVIPIQAIKLIETCWYFGDTFCGLYLFLIFELLSASLSNLVLIAVDRYVAVCHPLLYPQKITITKTLMSICLSWVCYSAYNTALIINNRYSETSHRTDECYGRCFIVMSFSWLVADLVMSFIFPCLIMITLYLMIFYVVHQQVKVMNSLMKGGKCVTEGSVKRKSESKAALTLGIIVTIYLLCYIPYYICSLVVNSSTAIHVMSWTVYVNSGMNPLVYALFYPWFKKTAKIIFTLKIFQPASSLINIFTELDM", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z335-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19r", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEHQETQYCFPNINSSCVKGRRYRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILFLAVNDLLIGLIVLPVEAIRLIERCWYFGETFCFLYLILIVLIFSASLSYLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNIAFVINNRNLNSSQKTDVCYGQCLIMMSFSWTIIDLSICFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGAKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTINVLMWNVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z339-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "si:ch211-139n6.11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKGKRSRHEYIIMYVFFLLLSAWTVILNLLVIISISHFKKLHSPTNLLILSLSVADLLVGLIVIPIEAIKQIETCWYFGATFCGINLIIIGVIFSASFSNLVLIAVDRYVAVCHPLLYPQKITTAKMLMSICLSWLYYSAYNAGLVVNNGYFDTAHRTDVCYGDCTVIMSFGWIVIDLFMSFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKCLTEISVKRKSESKAALTLGIIVLVYLFSYIPYYICTLSVNSVTTNNVLGWTVYANSGLNPLVYALFYPWFKKTAKIILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z8I1-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19s", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKGRRYRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILFLAVNDLLIGLIVLPVEAIRLIERCWYFGETFCFLYLILIVLIFSASLSYLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNIAFVINNRNLNSSQKTDVCYGQCLIMMSFSWTVIDLSICFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKCETEGSVKRKSESKAALTLGIIVSVYLLCYIPYYICTLLVSSSTTINVLMWNVHANSGLNPLVYAIFYPWFKKTAKLILTLKIFQPASSLINIFTENEL", "length": 335 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCQ8-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKEQHSTNGYIIYLFVSFLSAWTVFLNLLVIISISHFKKLHTPTNMIVLSLAVADLLIGLIVMPVEAVKLIETCWYFGDTFCGFTLILIGVIPSASLGNLVLIAVDRYAAVCHPLLYPQKITMANMLMSICLSWVYYSTYITTLVIYNRYFDTSHRTDECYGQCLVMMSFSWILTDLFVCFVFPCVLIITLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVKRKSESKAALTLGIIVSVYLLCWIPYYICTLTVNSSTVLSVLTWVLYANSGLNPLVYALFYPWFKKTVKHILTMTICQLASSLVNIFTEHEL", "length": 334 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QD04-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "Taar9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSDFSPEPPMELCYENVNGSCIKSSYAPWPRAILYGVLGLGALLAVFGNLLVIIAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVESCWYFGESYCKFHTCFDTSFCFASLFHLCCISIDRYIAVTDPLTYPTKFTVSVSGLCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKYQARKIEGTANQAQASSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSTTNLFSEEAGAG", "length": 348 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091113-50", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-50#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5QD16-1", "protein_name": "Trace amine-associated receptor 3", "gene_name": "Taar3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLIYIPEDLSSCPKFGNKSCPPTNRSFRVRMIMYLFMTGAMVITIFGNLVIIISISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSMVRSVESCWYFGDSFCKFHASFDMMLSLTSIFHLCSIAIDRFYAVCDPLHYTTTMTVSMIKRLLAFCWAAPALFSFGLVLSEANVSGMQSYEILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSRRHARALSDMPANTKGAVGKNLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPIIVLDLLVWLGYFNSTCNPLIHGFFYPWFRKALQFIVSGKIFRSNSDTANLFPEAH", "length": 343 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5QD24-1", "protein_name": "Trace amine-associated receptor 3", "gene_name": "Taar3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLIYIPEDLSSCPKFGNKSCPPTNRSFRVRLIMYLLMTGAMVITIFGNLVIIISISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSMVRSVESCWYFGDSFCKFHASFDMMLSLTSIFHLCSIAIDRFYAVCAPLHYTTTMTASMIKRLLFFCWAAPALFSFGLVLSEANVSGMQSYEILIACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSRRHARALGNMPENTKGAGRNLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPIIVLDLLVWLGYFNSTCNPLIHGFFYPWFRKALEHIVSGKIFRSNSDTANLFPEAH", "length": 342 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091113-50", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-50#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q923Y6-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "Taar9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELCYENVNGSCIKSSYSPWPRAILYAVLGLGALLAVFGNLLVITAILHFKQLHTPTNFLVASLACADFLVGVTVMPFSTVRSVEGCWYFGDTYCKFHTCFDTSFCFASLFHLCCISIDRYVAVTDPLTYPTKFTISVSGVCIALSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFLPTVVMVFLYGRIFLVAKQQARKIEGSANQPQASSESYKERVARRERKAAKTLGIAMAAFLVSWLPYIIDAVIDAYMNFITPAYVYEILVWCVYYNSAMNPLIYAFFYPWFRKAIKLIVSGKVFRADSSRTNLFSEEAGAG", "length": 338 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96RI9-1", "protein_name": "Trace amine-associated receptor 9", "gene_name": "TAAR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNNFSQAEAVELCYKNVNESCIKTPYSPGPRSILYAVLGFGAVLAAFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTVRSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGICIVLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIYAFFYQWFGKAIKLIVSGKVLRTDSSTTNLFSEEVETD", "length": 348 }, "evidence": [ { "id": "MGI:3527454", "url": "https://alliancegenome.org/gene/MGI:3527454#orthology", "database": "AGR" }, { "id": "HGNC:20977", "url": "https://alliancegenome.org/gene/HGNC:20977#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091113-50", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-50#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9P1P4-1", "protein_name": "Putative trace amine-associated receptor 3", "gene_name": "TAAR3P", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDLTYIPEDLSSCPKFVNKILSSHQPLFSCPGDNVFGYDWSHDYPLFGNLVIMVSISHFKQLHSPTNFLILSMATTDFLLGFVIMPYSIMRSVESCWYFGDGFCKFHTSFDMMLRLTSIFHLCSIAIDRFYAVCYPLHYTTKMTNSTIKQLLAFCWSVPALFSFGLVLSEADVSGMQSYKILVACFNFCALTFNKFWGTILFTTCFFTPGSIMVGIYGKIFIVSKQHARVISHVPENTKGAVKKHLSKKKDRKAAKTLGIVMGVFLACWLPCFLAVLIDPYLDYSTPILILDLLVWLRYFNSTCNPLIHGFFNPWFQKAFKYIVSGKIFSSHSETANLFPEAH", "length": 343 }, "evidence": [ { "id": "RGD:1359566", "url": "https://alliancegenome.org/gene/RGD:1359566#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "trace-amine receptor activity", "id": "GO:0001594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001594", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X3", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z8X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X3" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 300, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 177, "end_pos": 179 }, { "start_pos": 18, "end_pos": 20 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z8X7-1", "uniprot_ac": "A0A8M6Z8X7", "uniprot_id": "A0A8M6Z8X7_DANRE", "mass": { "chemical_mass": 37900.0, "monoisotopic_mass": 37900.0 }, "refseq": { "ac": "XP_017213588", "name": "trace amine-associated receptor 13c-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213588" }, "gene_names": [ { "name": "taar19u", "type": "recommended", "evidence": [ { "id": "A0A8M6Z8X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X7" } ] }, { "name": "taar19u", "type": "synonym", "evidence": [ { "id": "XP_017213588", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213588" } ] } ], "protein_names": [ { "name": "Trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "A0A8M6Z8X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X7/entry#names_and_taxonomy" } ] }, { "name": "trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "XP_017213588", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213588" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213588", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213588" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "taar19u", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060413-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z8X7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z8X7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "108191517", "url": "https://www.ncbi.nlm.nih.gov/gene/108191517", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108191517", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191517", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z8X7", "url": "https://www.orthodb.org/?gene=A0A8M6Z8X7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249:SF381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249:SF381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213588", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213588", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8X7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060413-1", "url": "https://zfin.org/ZDB-GENE-060413-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKGKRSRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLFVIPIQAIKLTETCWYFGDIFCVLYLILIGLIFSASLSNLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNTAFVVNNGYFDSSHRTDMCNGRCSVMVSFSWTVIDLFMCFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKRVTESSAKRKSESKAALTLGIIVTIYLLCYIPYYICSLFVISSTTITVLSWAVHANSGLNPLVYALFYSSFKKTVKHIFTLKIFQPVSFLFRIFK", "length": 331, "header": "tr|A0A8M6Z8X7-1|A0A8M6Z8X7_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=taar19u PE=3 SV=1 CANONICAL=A0A8M6Z8X7-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z8X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X7/entry#A0A8M6Z8X7-1", "sequence": { "sequence": "MAYETEDQETQYCFPDINSSCVKGKRSRHEYIIMYVFFSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLFVIPIQAIKLTETCWYFGDIFCVLYLILIGLIFSASLSNLVLIAVDRYVAVCHPLLYPQKITITNMLKSICLSWVCYSAYNTAFVVNNGYFDSSHRTDMCNGRCSVMVSFSWTVIDLFMCFIFPCLIMITLYLRIFYVVHQQVKVINSLMKGGKRVTESSAKRKSESKAALTLGIIVTIYLLCYIPYYICSLFVISSTTITVLSWAVHANSGLNPLVYALFYSSFKKTVKHIFTLKIFQPVSFLFRIFK", "length": 331, "header": "tr|A0A8M6Z8X7-1|A0A8M6Z8X7_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=taar19u PE=3 SV=1 CANONICAL=A0A8M6Z8X7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108191517", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191517", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PV58-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar19m", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAYETEDQETQYCFPNINSSCVKEKRSIREYIIMYLFSSLLSVWIVFLNLLVIISISHFKKLHTPTNMIILSLAVADLLIGLIVMPLQAIKQIETCWYFGESFCGINLILIGLIFSASFSNLVLIAVDRYVAVCHPLLYPRKITTAKMLMSILLSWLYYSGYNTGLVINNGYADTSYRTDMCYGECTIIMSFGWILTDMFMFFIFPCLIMITFYVRIFYVVHQQVKVMNSLMKGGKCVTEGSVKRKSESKAALTLGIIVTVYLLCYIPYYICTLSVNSVTAINVLGWIVYANSGVNPLVYALFYPWFKKTAKIILTLKIFEPASSLINIFK", "length": 331 }, "evidence": [ { "id": "RGD:620631", "url": "https://alliancegenome.org/gene/RGD:620631#orthology", "database": "AGR" }, { "id": "MGI:2429635", "url": "https://alliancegenome.org/gene/MGI:2429635#orthology", "database": "AGR" }, { "id": "HGNC:20978", "url": "https://alliancegenome.org/gene/HGNC:20978#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z0U9-1", "protein_name": "Trace amine-associated receptor 13c-like", "gene_name": "taar20b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKEQKGEQNKHLTGGDSLMAYETEDQETQYCFPDINSSCLKENRSSDEYNIIYLLVSLLSAWTVFLNLLVIISISHFKKLHTPTNMIILSLAVNDLLIGLVMPIEAFRLIETCWYFGDTFCGLYLFFVTLLLSASLGSLVLIAVDRYVAVCHPLLYTQKITMTKTFCLSICLSWVCFSAYLTGLININNQDFDTSHRTDVCYGQCIIMITFSWILTDLFVSFIFPCTLIFTLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVERKSESKAALTLGIIVLVYLLCYIPYYICSLTVNSSTALNVLIWIVYSNSGMNPLVYALFYPWFKKTVKLILTLKIFQQASSLINIFTEH", "length": 352 }, "evidence": [ { "id": "HGNC:20978", "url": "https://alliancegenome.org/gene/HGNC:20978#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QD13-1", "protein_name": "Trace amine-associated receptor 6", "gene_name": "Taar6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSNSSPPTVLQLCYENVTGSCVKTPYSPGSRVILYAVFGFGAVLAVFGNLMVMISILHFKQLHSPTNFLIASLACADFGVGISVMPFSMVRSIESCWYFGRSFCTFHTCCDVAFCYSSLFHLSFISIDRYIAVTDPLVYPTKFTVSVSGICIGVSWILPLVYSGAVFYTGVYDDGLEELSSALNCVGGCQVVVNQNWVLIDFLSFLIPTLVMIILYGNIFLVARQQAKKIENIGSKTESSSESYKARVARRERKAAKTLGITVVAFMISWLPYSIDSLVDAFMGFITPAYIYEICVWCAYYNSAMNPLIYALFYPWFKKAIKVIMSGQVFKNSSATMNLFSEQI", "length": 345 }, "evidence": [ { "id": "HGNC:20978", "url": "https://alliancegenome.org/gene/HGNC:20978#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91ZY1-1", "protein_name": "Histamine H4 receptor", "gene_name": "Hrh4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSESNGTDVLPLTAQVPLAFLMSLLAFAITIGNAVVILAFVADRNLRHRSNYFFLNLAISDFFVGVISIPLYIPHTLFNWNFGSGICMFWLITDYLLCTASVYSIVLISYDRYQSVSNAVRYRAQHTGILKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTEECEPGFVTEWYILAITAFLEFLLPVSLVVYFSVQIYWSLWKRGSLSRCPSHAGFIATSSRGTGHSRRTGLACRTSLPGLKEPAASLHSESPRGKSSLLVSLRTHMSGSIIAFKVGSFCRSESPVLHQREHVELLRGRKLARSLAVLLSAFAICWAPYCLFTIVLSTYRRGERPKSIWYSIAFWLQWFNSLINPFLYPLCHRRFQKAFWKILCVTKQPAPSQTQSVSS", "length": 391 }, "evidence": [ { "id": "RGD:620631", "url": "https://alliancegenome.org/gene/RGD:620631#orthology", "database": "AGR" }, { "id": "MGI:2429635", "url": "https://alliancegenome.org/gene/MGI:2429635#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060413-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91ZY2-1", "protein_name": "Histamine H4 receptor", "gene_name": "Hrh4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSESNSTGILPPAAQVPLAFLMSSFAFAIMVGNAVVILAFVVDRNLRHRSNYFFLNLAISDFLVGLISIPLYIPHVLFNWNFGSGICMFWLITDYLLCTASVYNIVLISYDRYQSVSNAVSYRAQHTGIMKIVAQMVAVWILAFLVNGPMILASDSWKNSTNTKDCEPGFVTEWYILTITMLLEFLLPVISVAYFNVQIYWSLWKRRALSRCPSHAGFSTTSSSASGHLHRAGVACRTSNPGLKESAASRHSESPRRKSSILVSLRTHMNSSITAFKVGSFWRSESAALRQREYAELLRGRKLARSLAILLSAFAICWAPYCLFTIVLSTYPRTERPKSVWYSIAFWLQWFNSFVNPFLYPLCHRRFQKAFWKILCVTKQPALSQNQSVSS", "length": 391 }, "evidence": [ { "id": "RGD:620631", "url": "https://alliancegenome.org/gene/RGD:620631#orthology", "database": "AGR" }, { "id": "MGI:2429635", "url": "https://alliancegenome.org/gene/MGI:2429635#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060413-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923Y5-1", "protein_name": "Trace amine-associated receptor 6", "gene_name": "Taar6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSNSSPPAVLQLCYENVNGSCVKTPYSPGPRVLLYAVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLIASLACADFWVGVSVMPFSMVRSIESCWYFGRSFCTFHTCCDVAFCYSSLFHLSFISIDRYIAVTDPLVYPTKFTVSVSGICISISWILPLAYSGAVFYTGVYADGLEEVSDAVNCVGGCQVVVNQNWVLIDFLSFLIPTLVMIILYGNIFLVARQQAKKIETVGNKAESSSESYKARVARRERKAAKTLGITVVAFMISWLPYSIDSLVDAFMGFITPAYIYEICVWCAYYNSAMNPLIYALFYPWFKKAIKVIMSGQVFKNSSATMNLFSEQI", "length": 345 }, "evidence": [ { "id": "HGNC:20978", "url": "https://alliancegenome.org/gene/HGNC:20978#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96RI8-1", "protein_name": "Trace amine-associated receptor 6", "gene_name": "TAAR6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSNSSLLVAVQLCYANVNGSCVKIPFSPGSRVILYIVFGFGAVLAVFGNLLVMISILHFKQLHSPTNFLVASLACADFLVGVTVMPFSMVRTVESCWYFGRSFCTFHTCCDVAFCYSSLFHLCFISIDRYIAVTDPLVYPTKFTVSVSGICISVSWILPLMYSGAVFYTGVYDDGLEELSDALNCIGGCQTVVNQNWVLTDFLSFFIPTFIMIILYGNIFLVARRQAKKIENTGSKTESSSESYKARVARRERKAAKTLGVTVVAFMISWLPYSIDSLIDAFMGFITPACIYEICCWCAYYNSAMNPLIYALFYPWFRKAIKVIVTGQVLKNSSATMNLFSEHI", "length": 345 }, "evidence": [ { "id": "HGNC:20978", "url": "https://alliancegenome.org/gene/HGNC:20978#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060413-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060413-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9H3N8-1", "protein_name": "Histamine H4 receptor", "gene_name": "HRH4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPDTNSTINLSLSTRVTLAFFMSLVAFAIMLGNALVILAFVVDKNLRHRSSYFFLNLAISDFFVGVISIPLYIPHTLFEWDFGKEICVFWLTTDYLLCTASVYNIVLISYDRYLSVSNAVSYRTQHTGVLKIVTLMVAVWVLAFLVNGPMILVSESWKDEGSECEPGFFSEWYILAITSFLEFVIPVILVAYFNMNIYWSLWKRDHLSRCQSHPGLTAVSSNICGHSFRGRLSSRRSLSASTEVPASFHSERQRRKSSLMFSSRTKMNSNTIASKMGSFSQSDSVALHQREHVELLRARRLAKSLAILLGVFAVCWAPYSLFTIVLSFYSSATGPKSVWYRIAFWLQWFNSFVNPLLYPLCHKRFQKAFLKIFCIKKQPLPSQHSRSVSS", "length": 390 }, "evidence": [ { "id": "RGD:620631", "url": "https://alliancegenome.org/gene/RGD:620631#orthology", "database": "AGR" }, { "id": "MGI:2429635", "url": "https://alliancegenome.org/gene/MGI:2429635#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "trace-amine receptor activity", "id": "GO:0001594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001594", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8X7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z8X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8X7" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 48, "end_pos": 300, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z8Y1-1", "uniprot_ac": "A0A8M6Z8Y1", "uniprot_id": "A0A8M6Z8Y1_DANRE", "mass": { "chemical_mass": 40207.0, "monoisotopic_mass": 40207.0 }, "refseq": { "ac": "XP_017213593", "name": "trace amine-associated receptor 13c-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213593" }, "gene_names": [ { "name": "taar19q", "type": "recommended", "evidence": [ { "id": "A0A8M6Z8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8Y1" } ] }, { "name": "taar19q", "type": "synonym", "evidence": [ { "id": "XP_017213593", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213593" } ] } ], "protein_names": [ { "name": "Trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "A0A8M6Z8Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8Y1/entry#names_and_taxonomy" } ] }, { "name": "trace amine-associated receptor 13c-like", "type": "synonym", "evidence": [ { "id": "XP_017213593", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213593" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017213593.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213593", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213593" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8Y1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "taar19q", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8Y1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060413-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060413-13", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z8Y1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z8Y1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15055", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15055", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "108191520", "url": "https://www.ncbi.nlm.nih.gov/gene/108191520", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009132", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009132", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050569", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108191520", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191520", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z8Y1", "url": "https://www.orthodb.org/?gene=A0A8M6Z8Y1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24249:SF381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24249:SF381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213593", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213593", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8Y1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z8Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060413-13", "url": "https://zfin.org/ZDB-GENE-060413-13", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKGQKGEQNKLLTGVDSLMAYETEDQETQYCFPDINSSCVKGKRSIQEYIIMYVFFSLLSVWTVFLNLLVIISISHFKKLHTPTNMIILSLAVADLLIGLIVMPIKAIRQVETCWYFGDTFCGLNSILIGAIFSATLSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMFICLCWIYYSAYNTAVVMNNRYFDTSNRTDMCYGDCSVIMSFGWILTDLFMSFILPCLIMISLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVKRKSESKAALTLGIIVLVYLLCYIPYYICALSVNSSTTITVLEWTVYTNSGLNPLVYALFYHWFKKTAKLILTLKIFHPESSLINVFTENEL", "length": 353, "header": "tr|A0A8M6Z8Y1-1|A0A8M6Z8Y1_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=taar19q PE=3 SV=3 CANONICAL=A0A8M6Z8Y1-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z8Y1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z8Y1/entry#A0A8M6Z8Y1-1", "sequence": { "sequence": "MKGQKGEQNKLLTGVDSLMAYETEDQETQYCFPDINSSCVKGKRSIQEYIIMYVFFSLLSVWTVFLNLLVIISISHFKKLHTPTNMIILSLAVADLLIGLIVMPIKAIRQVETCWYFGDTFCGLNSILIGAIFSATLSNLVLIAVDRYVAVCHPLLYPQKITMAKMLMFICLCWIYYSAYNTAVVMNNRYFDTSNRTDMCYGDCSVIMSFGWILTDLFMSFILPCLIMISLYLRIFYVVHQQVKVINSLMKGGKCVTEGSVKRKSESKAALTLGIIVLVYLLCYIPYYICALSVNSSTTITVLEWTVYTNSGLNPLVYALFYHWFKKTAKLILTLKIFHPESSLINVFTENEL", "length": 353, "header": "tr|A0A8M6Z8Y1-1|A0A8M6Z8Y1_DANRE Isoform 1 of Trace amine-associated receptor 13c-like OS=Danio rerio OX=7955 GN=taar19q PE=3 SV=3 CANONICAL=A0A8M6Z8Y1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108191520", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108191520", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213655", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213655" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z901", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z901" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100534832", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z901", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z901", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z901", "database": "AlphaFoldDB", "categories": [] }, { "id": "100534832", "url": "https://www.ncbi.nlm.nih.gov/gene/100534832", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": 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This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017214052.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214052", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214052" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z916", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z916" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108179108", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z916", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z916", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z916", "database": "AlphaFoldDB", "categories": [] }, { "id": "108179108", "url": "https://www.ncbi.nlm.nih.gov/gene/108179108", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:108179108", "url": 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MKLHIFKYDSFRCHARLCIEPAIVHKWRNWQSEMLEQLSRRENVIVGGDKRADSPGHSAKYGSYTMMDLATNTVVDLQLVQSNEVGGSYHMEKEGLKRSLDLLDARGVRLECIITDRHPQIQKYLRDRNVTQFYDVWHIEKGISKKLDKICQIKGCEKLRKWLRSIKNHIYWTAASSTTGPERVAKWTSILNHVHEDPNFPAYLHPQRISRDKNKWLSAATMPFYKLEKVLANKRILKDVAKLSPHHQASTVEAFHSVLLRFAPKNVVFPFLGMLCRLYLAALHYNENAGRPQATSATGKPIYKLAFPKAKKGEYRVREVKTQQTFGYVKELLDLIFNQVFVDPSPYVDEVLGIHIPPALSSACDLPEMEEAISSRVTRFNQ", "length": 382, "header": "tr|A0A8M6Z916-1|A0A8M6Z916_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108179108 PE=4 SV=1 CANONICAL=A0A8M6Z916-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z916-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z916/entry#A0A8M6Z916-1", "sequence": { "sequence": "MKLHIFKYDSFRCHARLCIEPAIVHKWRNWQSEMLEQLSRRENVIVGGDKRADSPGHSAKYGSYTMMDLATNTVVDLQLVQSNEVGGSYHMEKEGLKRSLDLLDARGVRLECIITDRHPQIQKYLRDRNVTQFYDVWHIEKGISKKLDKICQIKGCEKLRKWLRSIKNHIYWTAASSTTGPERVAKWTSILNHVHEDPNFPAYLHPQRISRDKNKWLSAATMPFYKLEKVLANKRILKDVAKLSPHHQASTVEAFHSVLLRFAPKNVVFPFLGMLCRLYLAALHYNENAGRPQATSATGKPIYKLAFPKAKKGEYRVREVKTQQTFGYVKELLDLIFNQVFVDPSPYVDEVLGIHIPPALSSACDLPEMEEAISSRVTRFNQ", "length": 382, "header": "tr|A0A8M6Z916-1|A0A8M6Z916_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108179108 PE=4 SV=1 CANONICAL=A0A8M6Z916-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108179108", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179108", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z959-1", "uniprot_ac": "A0A8M6Z959", "uniprot_id": "A0A8M6Z959_DANRE", "mass": { "chemical_mass": 45179.0, "monoisotopic_mass": 45179.0 }, "refseq": { "ac": "XP_021335517", "name": "DEP domain-containing mTOR-interacting protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335517" }, "gene_names": [ { "name": "si:dkeyp-97e7.9", "type": "recommended", "evidence": [ { "id": "A0A8M6Z959", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z959" } ] }, { "name": "si:dkeyp-97e7.9", "type": "synonym", "evidence": [ { "id": "XP_021335517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335517" } ] } ], "protein_names": [ { "name": "DEP domain-containing mTOR-interacting protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021335517", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335517" }, { "id": "A0A8M6Z959", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z959/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021335517", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335517" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z959", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z959" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkeyp-97e7.9", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z959", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131121-398", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-398", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100151344", "url": "https://www.ncbi.nlm.nih.gov/gene/100151344", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036390", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036390", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100151344", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100151344", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DIVHHCD", "url": "https://omabrowser.org/oma/group/DIVHHCD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z959", "url": "https://www.orthodb.org/?gene=A0A8M6Z959", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22829:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22829:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00610", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00610", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021335517", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335517", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z959", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z959", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z959-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z959-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GT34", "url": "https://www.uniprot.org/uniprotkb/A0AC58GT34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GT34-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GT34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131121-398", "url": "https://zfin.org/ZDB-GENE-131121-398", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMTRNLKAEVMIAGEQLRLRLHDNKLIKDRRHHLRTYPNCFVAQELINWLIAHKEASDRDTAVRLMQHLMDYDIIHHVCDKWPVFRDAKYLYRFRKDDGTFPFNIEVKIFMRGQRLYEQVISSKDSISQVRQEEGVAYERSFPGYMLIDWLLQNSEIESRRQGLDLCKALLEHDIIQHVSQKHHFFDSGLLYQFCINFRRRRRLSELLHETENEEVECATHQTQEDQPDSPFTLRKSPPSVGNSDFLCVQPNKDSSLSRTVRCGSVTHQQHSSCGGYSASLNAALAVRCNPTSVLKRHVTCEELLLPDAPYVKRVLTILGDALGWGFVVRGKTPCYVQAVDPGGPAATAGVKVRQFVCRVNGLGVLHLDYRTLSRLVMTGPRVVTLEVMEPMD", "length": 393, "header": "tr|A0A8M6Z959-1|A0A8M6Z959_DANRE Isoform 1 of DEP domain-containing mTOR-interacting protein isoform X1 OS=Danio rerio OX=7955 GN=si:dkeyp-97e7.9 PE=4 SV=1 CANONICAL=A0A8M6Z959-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z959-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z959/entry#A0A8M6Z959-1", "sequence": { "sequence": "MMTRNLKAEVMIAGEQLRLRLHDNKLIKDRRHHLRTYPNCFVAQELINWLIAHKEASDRDTAVRLMQHLMDYDIIHHVCDKWPVFRDAKYLYRFRKDDGTFPFNIEVKIFMRGQRLYEQVISSKDSISQVRQEEGVAYERSFPGYMLIDWLLQNSEIESRRQGLDLCKALLEHDIIQHVSQKHHFFDSGLLYQFCINFRRRRRLSELLHETENEEVECATHQTQEDQPDSPFTLRKSPPSVGNSDFLCVQPNKDSSLSRTVRCGSVTHQQHSSCGGYSASLNAALAVRCNPTSVLKRHVTCEELLLPDAPYVKRVLTILGDALGWGFVVRGKTPCYVQAVDPGGPAATAGVKVRQFVCRVNGLGVLHLDYRTLSRLVMTGPRVVTLEVMEPMD", "length": 393, "header": "tr|A0A8M6Z959-1|A0A8M6Z959_DANRE Isoform 1 of DEP domain-containing mTOR-interacting protein isoform X1 OS=Danio rerio OX=7955 GN=si:dkeyp-97e7.9 PE=4 SV=1 CANONICAL=A0A8M6Z959-1" }, "locus": {} }, { "isoform_ac": "A0AC58GT34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z959/entry#A0AC58GT34-1", "sequence": { "sequence": "MMTRNLKAEVMIAGEQLRLRLHDNKLIKDRRHHLRTYPNCFVAQELINWLIAHKEASDRDTAVRLMQHLMDYDIIHHVCDKWPVFRDAKYLYRFRKDDGTFPFNIEVKIFMRGQRLYEQVISSKDSISQNSEIESRRQGLDLCKALLEHDIIQHVSQKHHFFDSGLLYQFCINFRRRRRLSELLHETENEEVECATHQTQEDQPDSPFTLRKSPPSVGNSDFLCVQPNKDSSLSRTVRCGSVTHQQHSSCGGYSASLNAALAVRCNPTSVLKRHVTCEELLLPDAPYVKRVLTILGDALGWGFVVRGKTPCYVQAVDPGGPAATAGVKVRQFVCRVNGLGVLHLDYRTLSRLVMTGPRVVTLEVMEPMD", "length": 369, "header": "tr|A0AC58GT34-1|A0AC58GT34_DANRE Computationally mapped isoform of DEP domain-containing mTOR-interacting protein isoform X2 OS=Danio rerio OX=7955 GN=si:dkeyp-97e7.9 PE=4 SV=1 CANONICAL=A0A8M6Z959-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100151344", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100151344", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NAC5-1", "protein_name": "DEP domain-containing mTOR-interacting protein", "gene_name": "LOC419242", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGCAVPPARSRPQPGMELLSGALKKRATEQHYRAEVMIAGEQLRLRLHDGKLIKDRRYHLRTYPNCFVAKELTDWLIDHKEAPDRETGIRLMQKLMDHYIIHHVCDEHSDYKDAKLLYRFRKDDGTFPLSKDVKVFMRGQSLYEKLVSVEGSILKVREENSVKYQRAFLGCEMVEWLVQEGEAESRREAVELGQALLEHGIIQHVSNRHRFLDTDILYQFWINFRRRRRLTELLSENSSRALSESPDSPFCLRKLNPEPGNTSFLSVQPNKEIKVVSAVRRSSITSLAGNSNPYFSITPTLVFPPVAECNPKSVLKRPVTNEELLSPGAPYVKKTLTIVGDAVGWGFVVRGGRPCHIQAVDPGGPAAAAGMKVCQFVFSVNGMYVLHLDYQTISSLIMTGPRTLVMEIMEAIE", "length": 413 }, "evidence": [ { "id": "A0A8M6Z959", "url": "https://omabrowser.org/oma/group/A0A8M6Z959/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z959", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z959" } ], "pmid": "" }, { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z959", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z959" } ], "pmid": "" }, { "name": "protein serine/threonine kinase inhibitor activity", "id": "GO:0030291", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030291", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z959", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z959" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z959", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z959" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "G protein-coupled 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This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017214356.1. 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Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017214027.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214027", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214027" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9E1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9E1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gjz1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9E1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130603-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130603-55", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6Z9E1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z9E1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100332365", "url": 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"MAAIVTGLIPILRTAVESTATYKGRTMWFGLLCIRLVTVFLAQFPWKSISEDFHCNSTLPYCTKACFNKHFDSSIVMAWHFIFILLVLSVLLMELFSSHLRSSFQKKKEREMASQSEQGGVTDPTVTIGGRMMIDLHKSKSSVMVYLFCIMLRIAVELLFVYVLLSWVLPKLNEEPHICEAHTFDGCSVQQCLVRGIAEKKMSVYALLFASALVIITSSLFCLYSVAHYLCDC", "length": 233, "header": "tr|A0A8M6Z9E1-1|A0A8M6Z9E1_DANRE Isoform 1 of Gap junction beta-5 protein OS=Danio rerio OX=7955 GN=gjz1 PE=4 SV=2 CANONICAL=A0A8M6Z9E1-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z9E1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9E1/entry#A0A8M6Z9E1-1", "sequence": { "sequence": "MAAIVTGLIPILRTAVESTATYKGRTMWFGLLCIRLVTVFLAQFPWKSISEDFHCNSTLPYCTKACFNKHFDSSIVMAWHFIFILLVLSVLLMELFSSHLRSSFQKKKEREMASQSEQGGVTDPTVTIGGRMMIDLHKSKSSVMVYLFCIMLRIAVELLFVYVLLSWVLPKLNEEPHICEAHTFDGCSVQQCLVRGIAEKKMSVYALLFASALVIITSSLFCLYSVAHYLCDC", "length": 233, "header": "tr|A0A8M6Z9E1-1|A0A8M6Z9E1_DANRE Isoform 1 of Gap junction beta-5 protein OS=Danio rerio OX=7955 GN=gjz1 PE=4 SV=2 CANONICAL=A0A8M6Z9E1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100332365", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100332365", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cell-cell signaling", "id": "GO:0007267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007267", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9E1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9E1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "connexin complex", "id": "GO:0005922", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005922", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9E1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9E1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "gap junction channel activity", "id": "GO:0005243", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005243", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9E1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9E1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z9E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9E1" }, { "id": "PF00029", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00029" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Connexin N-terminal", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 224, "start_aa": "Thr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z9F1-1", "uniprot_ac": "A0A8M6Z9F1", "uniprot_id": "A0A8M6Z9F1_DANRE", "mass": { "chemical_mass": 88346.0, "monoisotopic_mass": 88346.0 }, "refseq": { "ac": "XP_017214522", "name": "protocadherin beta-16-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214522" }, "gene_names": [ { "name": "LOC108192077", "type": "recommended", "evidence": [ { "id": "A0A8M6Z9F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9F1" } ] }, { "name": "LOC108192077", "type": "synonym", "evidence": [ { "id": "XP_017214522", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214522" } ] } ], "protein_names": [ { "name": "Protocadherin beta-16-like", "type": "synonym", "evidence": [ { "id": "A0A8M6Z9F1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9F1/entry#names_and_taxonomy" } ] }, { "name": "protocadherin beta-16-like", "type": "synonym", "evidence": [ { "id": "XP_017214522", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214522" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017214522.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214522", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214522" } ] }, { "annotation": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9F1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9F1#function" }, { "database": "UniProtKB", "id": "ARBA00003436", "url": "https://www.uniprot.org/uniprotkb/ARBA00003436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9F1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9F1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108192077", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9F1", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z9F1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z9F1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "108192077", "url": "https://www.ncbi.nlm.nih.gov/gene/108192077", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108192077", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108192077", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z9F1", "url": "https://www.orthodb.org/?gene=A0A8M6Z9F1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF296", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF296", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017214522", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214522", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z9F1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9F1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z9F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9F1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSDRTMARQVLLFIWFLSLSSALGQVSYSIPEEMAKGSLVGNIAQDLGLDLKRLKSGKARIYTGDSAEYIELNKERGVLLIKERIDREALCGQTTPCALHLQIILENPMEFFTVTIEITDVNDNTPIFKKRSVVFKISESVILGSKFMLEPAVDLDVGINGLQSYMLKPTDNLSLKFKNQAGDGKHVEMVLQKPLDREKQNEINLVLTAVDGGDPQLSGSIDIHITVLDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANMEDDVQRLFAINRDNGQVSVVGIIDFERARNYEIRVQASDQGGLTDSCKIIVDVVDINDNAPVINIMSKTNVIAENSASETVVTMINVQDVDSGDNGKVQCSVNENIPFSLKSTNNNFFSLVTDGDLDRERESEYNISVTCADEGVPSLSSSVTLSLQISDVNDNAPVFEQSSYQASVQENNTPGLSIFTVRARDADFNQNARVSYILEDSSVNGVPVSSLVSVSADSGVIHAVRSFDYEQIKEFQFRVKAQDGGSPPLSSNASVKILIQDQNDNAPQVLYPVQSGASVVAEIVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDRALFEVGAQNGEIRTVRQVTDKDAVKQRLTVVVEDNGQPSRSATVNVNVAVADSFPEVLSEFTDFTHDKEYNDNLTFSLVLALAVVSFLFIVSVIAILSVKCYRWRRERMFYKSGANLPVIPYYPPLYADVGGTGTLQHVYNYEVCRTTDSRKSDVKYGRPCSESIISLDTSGTQTLTHAQRGKLVSGDFDDQVRLSY", "length": 805, "header": "tr|A0A8M6Z9F1-1|A0A8M6Z9F1_DANRE Isoform 1 of Protocadherin beta-16-like OS=Danio rerio OX=7955 GN=LOC108192077 PE=4 SV=2 CANONICAL=A0A8M6Z9F1-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z9F1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9F1/entry#A0A8M6Z9F1-1", "sequence": { "sequence": "MSDRTMARQVLLFIWFLSLSSALGQVSYSIPEEMAKGSLVGNIAQDLGLDLKRLKSGKARIYTGDSAEYIELNKERGVLLIKERIDREALCGQTTPCALHLQIILENPMEFFTVTIEITDVNDNTPIFKKRSVVFKISESVILGSKFMLEPAVDLDVGINGLQSYMLKPTDNLSLKFKNQAGDGKHVEMVLQKPLDREKQNEINLVLTAVDGGDPQLSGSIDIHITVLDANDNAPVFMQSVYKATVTENAPKDTIVSTVSATDADEGINSKIEYSIANMEDDVQRLFAINRDNGQVSVVGIIDFERARNYEIRVQASDQGGLTDSCKIIVDVVDINDNAPVINIMSKTNVIAENSASETVVTMINVQDVDSGDNGKVQCSVNENIPFSLKSTNNNFFSLVTDGDLDRERESEYNISVTCADEGVPSLSSSVTLSLQISDVNDNAPVFEQSSYQASVQENNTPGLSIFTVRARDADFNQNARVSYILEDSSVNGVPVSSLVSVSADSGVIHAVRSFDYEQIKEFQFRVKAQDGGSPPLSSNASVKILIQDQNDNAPQVLYPVQSGASVVAEIVPRSADVGYLVTKVVAVDVDSGQNAWLSYKLHKATDRALFEVGAQNGEIRTVRQVTDKDAVKQRLTVVVEDNGQPSRSATVNVNVAVADSFPEVLSEFTDFTHDKEYNDNLTFSLVLALAVVSFLFIVSVIAILSVKCYRWRRERMFYKSGANLPVIPYYPPLYADVGGTGTLQHVYNYEVCRTTDSRKSDVKYGRPCSESIISLDTSGTQTLTHAQRGKLVSGDFDDQVRLSY", "length": 805, "header": "tr|A0A8M6Z9F1-1|A0A8M6Z9F1_DANRE Isoform 1 of Protocadherin beta-16-like OS=Danio rerio OX=7955 GN=LOC108192077 PE=4 SV=2 CANONICAL=A0A8M6Z9F1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108192077", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108192077", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9F1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9F1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9F1", "url": 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Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017214529.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214529", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214529" } ] }, { "annotation": "Potential calcium-dependent cell-adhesion protein. 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GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017214140.1. 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"MLSLCFHLFAVLVICADCNENRDISYTFKRWNALDQPLQEQLAIVYKEMESLKQEQSVMKQKQEALSQVLPYCSQNPIDTDVELNLTSLQTGTSHPLSAFTQNVDGDEGSGEDDSENPADPCFHYAALDQSWRATNYSTRNVACDRRVDWKGWYRLFYRGKTIQMPERCVKVEKCGTHSPLWLDGGHPRIRDGVVTRKVCGNWKNNCCMFKSNPIQVKACRGNYYVYKFVKPVACHLAYCSDINTLVCGKCKKSESCISRDKITYMCQKNKRRVKANVHFFATYPASIAGKVNKIVFRKVYVNQGQAFNPRTGIFRAPVSGVYQFFFSTQTGGSGATDLWLVVNNYWVAVSHSNVQGSSSVGNLSTYMTTLRKGAIVYVTHNRGRSWANSASNTIAFGGSLLMVRNI", "length": 407, "header": "tr|A0A8M6Z9G7-1|A0A8M6Z9G7_DANRE Isoform 1 of C1q domain-containing protein OS=Danio rerio OX=7955 GN=LOC100538338 PE=4 SV=1 CANONICAL=A0A8M6Z9G7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100538338", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100538338", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z9G7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9G7" }, { "id": "PS50871", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50871" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C1q", "eco_id": "ECO_0000259", "start_pos": 273, "end_pos": 407, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 136, "end_pos": 138 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M6Z9V1-1", "uniprot_ac": "A0A8M6Z9V1", "uniprot_id": "A0A8M6Z9V1_DANRE", "mass": { "chemical_mass": 88175.0, "monoisotopic_mass": 88175.0 }, "refseq": { "ac": "XP_017214534", "name": "protocadherin gamma-A5-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214534" }, "gene_names": [ { "name": "LOC108192086", "type": "recommended", "evidence": [ { "id": "A0A8M6Z9V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1" } ] }, { "name": "LOC108192086", "type": "synonym", "evidence": [ { "id": "XP_017214534", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214534" } ] } ], "protein_names": [ { "name": "Protocadherin gamma-A5-like", "type": "synonym", "evidence": [ { "id": "A0A8M6Z9V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1/entry#names_and_taxonomy" } ] }, { "name": "protocadherin gamma-A5-like", "type": "synonym", "evidence": [ { "id": "XP_017214534", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214534" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_017214534.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017214534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214534" } ] }, { "annotation": "Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9V1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1#function" }, { "database": "UniProtKB", "id": "ARBA00003436", "url": "https://www.uniprot.org/uniprotkb/ARBA00003436#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9V1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108192086", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1", "locus": {} } ], "crossref": [ { "id": "A0A8M6Z9V1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M6Z9V1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "108192086", "url": "https://www.ncbi.nlm.nih.gov/gene/108192086", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050174", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050174", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108192086", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108192086", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z9V1", "url": "https://www.orthodb.org/?gene=A0A8M6Z9V1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24028:SF337", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24028:SF337", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16492", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16492", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017214534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017214534", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z9V1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z9V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKTLAMDSGGQRRGWECCWIFLFSLVCFGQQASAQIRYTVPEEVKEGSVVGNCAKDLGLDVSALADRRFRIVSGSNDALFEVNQNNGVLYVSKQIDREQVCDGNAACLFNLKVVVEKPLEVHYVEVEITDVNDHSPSFHDKDLYLEVWENTVTGTRFELQTARDLDVGVNSVRFYQLSKNAHFDLEIKDSVYGDKTPFLVLQKALDRETTEMHRLLLTAVDGGAPPKSGTLNITVFVLDVNDNRPICSSDTTTITLRENAAMDTVVTIMNASDADSGINGEVEYTYGRNMKPKVLDIFNLDRKSGEIQVKGLIDFEENEIYSLIIRASDKGVPPLNTDCQLIIKVEDVNDNKPEIQVTSLSNVVMEDAKVGTVISLISVSDKDSGINGKVVCSLSDNVPFELKPSIQENMYSLVTKERLDRELVPEYDIKITATDLGNPPLSTYKSMLVQVSDVNDNIPEFSSNPLELYLTENNPPGASIFSVSASDKDINENAAITYHIIRGGGTHTDMSTVMNINSETGVIHALKRFDFETVKKFHFHVLATDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSEHSLFALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNVSLSATATVIVKVVEPKEAFAAFDVKNAEKDEEENNVTFYLIITLGSVSVLFVISIIVLIVMQCSKSTDYSSKYLQDTNYDGTLCHSIQYRSGDKRYMLVGPRMSIGSTIAPGSNRNTLVIPDRRRRDSGETHRGY", "length": 796, "header": "tr|A0A8M6Z9V1-1|A0A8M6Z9V1_DANRE Isoform 1 of Protocadherin gamma-A5-like OS=Danio rerio OX=7955 GN=LOC108192086 PE=4 SV=2 CANONICAL=A0A8M6Z9V1-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z9V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1/entry#A0A8M6Z9V1-1", "sequence": { "sequence": "MKTLAMDSGGQRRGWECCWIFLFSLVCFGQQASAQIRYTVPEEVKEGSVVGNCAKDLGLDVSALADRRFRIVSGSNDALFEVNQNNGVLYVSKQIDREQVCDGNAACLFNLKVVVEKPLEVHYVEVEITDVNDHSPSFHDKDLYLEVWENTVTGTRFELQTARDLDVGVNSVRFYQLSKNAHFDLEIKDSVYGDKTPFLVLQKALDRETTEMHRLLLTAVDGGAPPKSGTLNITVFVLDVNDNRPICSSDTTTITLRENAAMDTVVTIMNASDADSGINGEVEYTYGRNMKPKVLDIFNLDRKSGEIQVKGLIDFEENEIYSLIIRASDKGVPPLNTDCQLIIKVEDVNDNKPEIQVTSLSNVVMEDAKVGTVISLISVSDKDSGINGKVVCSLSDNVPFELKPSIQENMYSLVTKERLDRELVPEYDIKITATDLGNPPLSTYKSMLVQVSDVNDNIPEFSSNPLELYLTENNPPGASIFSVSASDKDINENAAITYHIIRGGGTHTDMSTVMNINSETGVIHALKRFDFETVKKFHFHVLATDSGSPSLSSNVTVNVFILDQNDNVPVILYPVSANGSAEGVEEIPRNVNAGHLVTKVRAYDADIGYNGWLLFSLQEVSEHSLFALDRYTGQIRTLRSFTETDEAQHKLVILVKDNGNVSLSATATVIVKVVEPKEAFAAFDVKNAEKDEEENNVTFYLIITLGSVSVLFVISIIVLIVMQCSKSTDYSSKYLQDTNYDGTLCHSIQYRSGDKRYMLVGPRMSIGSTIAPGSNRNTLVIPDRRRRDSGETHRGY", "length": 796, "header": "tr|A0A8M6Z9V1-1|A0A8M6Z9V1_DANRE Isoform 1 of Protocadherin gamma-A5-like OS=Danio rerio OX=7955 GN=LOC108192086 PE=4 SV=2 CANONICAL=A0A8M6Z9V1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108192086", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108192086", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9V1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9V1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9V1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9V1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9V1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1" } ], "pmid": "" }, { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8M6Z9V1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 554, "end_pos": 556, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 660, "end_pos": 662, "annotation": "n_glycosylation_sequon" }, { "start_pos": 696, "end_pos": 698, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M6Z9V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z9V1" }, { "id": "PS50268", "database": "PROSITE", "url": 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Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"url": "https://www.uniprot.org/uniprotkb/A0A8M9P744", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P744-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P744-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HC67", "url": "https://www.uniprot.org/uniprotkb/A0AC58HC67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HC67-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HC67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HC76", "url": "https://www.uniprot.org/uniprotkb/A0AC58HC76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HC76-1", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HC97-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HC97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCA4", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCA4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCA6", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCA6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCA9", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCA9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCA9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFCPFCGKHMSTLTRFCFTFGRCFEFLKDADQTETPGMSRPPDRAKQAEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERDAPRHSSTIQPGQITISDDEDLDPPETGPENTSCYSKYTDLYLPNVEQENEEPVAVNVNNFQHTAMEETDITLPDIVANLSLPIDHKMVSRFNISRANVWDGAVRGFKRTTYSETCDMLVKFTDDTGVLEEGLDTGGPRREFLTLLMKHLKDRPIFDGPEGH", "length": 400, "header": "tr|A0A8M9PIF9-1|A0A8M9PIF9_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=2 CANONICAL=A0A8M9PIF9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9NYH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9/entry#A0A8M9NYH7-1", "sequence": { "sequence": "MFCPFCGKHMSTLTRFCFTFGRCFEFLKDADQTETPGMSRPPDRAKQEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERDAPRHSSTIQPGQITISDDEDLDPPETGPENTSCYSKYTDLYLPNVEQENEEPVAVNVNNFQHTAMEETDITLPDIVANLSLPIDHKMVSRFNISRANVWDGAVRGFKRTTYSETCDMLVKFTDDTGVLEEGLDTGGPRREFLTLLMKHLKDRPIFDGPEGH", "length": 399, "header": "tr|A0A8M9NYH7-1|A0A8M9PIF9_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=2 CANONICAL=A0A8M9PIF9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P744-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9/entry#A0A8M9P744-1", "sequence": { "sequence": "MFCPFCGKHMSTLTRFCFTFGRCFEFLKDADQTETPGMSRPPDRAKQAEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERDAPRHSSTIQPGQITISDDEDLDPPETGPENTSCYREETDITLPDIVANLSLPIDHKMVSRFNISRANVWDGAVRGFKRTTYSETCDMLVKFTDDTGVLEEGLDTGGPRREFLTLLMKHLKDRPIFDGPEGH", "length": 370, "header": "tr|A0A8M9P744-1|A0A8M9P744_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=2 CANONICAL=A0A8M9PIF9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PIF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9/entry#A0A8M9PIF9-1", "sequence": { "sequence": "MFCPFCGKHMSTLTRFCFTFGRCFEFLKDADQTETPGMSRPPDRAKQAEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERDAPRHSSTIQPGQITISDDEDLDPPETGPENTSCYSKYTDLYLPNVEQENEEPVAVNVNNFQHTAMEETDITLPDIVANLSLPIDHKMVSRFNISRANVWDGAVRGFKRTTYSETCDMLVKFTDDTGVLEEGLDTGGPRREFLTLLMKHLKDRPIFDGPEGH", "length": 400, "header": "tr|A0A8M9PIF9-1|A0A8M9PIF9_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=2 CANONICAL=A0A8M9PIF9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HC67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9/entry#A0AC58HC67-1", "sequence": { "sequence": "MSRPPDRAKQEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERDAPRHSSTIQPGQITISDDEDLDPPETGPENTSCYSKYTDLYLPNVEQENEEPVAVNVNNFQHTAMEETDITLPDIVANLSLPIDHKMVSRFNISRANVWDGAVRGFKRTTYSETCDMLVKFTDDTGVLEEGLDTGGPRREFLTLLMKHLKDRPIFDGPEGH", "length": 362, "header": "tr|A0AC58HC67-1|A0AC58HC67_DANRE Computationally mapped isoform of Uncharacterized protein isoform X5 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=1 CANONICAL=A0A8M9PIF9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HC76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9/entry#A0AC58HC76-1", "sequence": { "sequence": "MFCPFCGKHMSTLTRFCFTFGRCFEFLKDADQTETPGMSRPPDRAKQAEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERAFTTRQRAI", "length": 247, "header": "tr|A0AC58HC76-1|A0AC58HC76_DANRE Computationally mapped isoform of Uncharacterized protein isoform X9 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=1 CANONICAL=A0A8M9PIF9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HC79-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9/entry#A0AC58HC79-1", "sequence": { "sequence": "MFCPFCGKHMSTLTRFCFTFGRCFEFLKDADQTETPGMSRPPDRAKQEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERAFTTRQRAI", "length": 246, "header": "tr|A0AC58HC79-1|A0AC58HC79_DANRE Computationally mapped isoform of Uncharacterized protein isoform X11 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=1 CANONICAL=A0A8M9PIF9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HC86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9/entry#A0AC58HC86-1", "sequence": { "sequence": "MSRPPDRAKQEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERDAPRHSSTIQPGQITISDDEDLDPPETGPENTSCYREETDITLPDIVANLSLPIDHKMVSRFNISRANVWDGAVRGFKRTTYSETCDMLVKFTDDTGVLEEGLDTGGPRREFLTLLMKHLKDRPIFDGPEGH", "length": 332, "header": "tr|A0AC58HC86-1|A0AC58HC86_DANRE Computationally mapped isoform of Uncharacterized protein isoform X8 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=1 CANONICAL=A0A8M9PIF9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HC89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9/entry#A0AC58HC89-1", "sequence": { "sequence": "MSRPPDRAKQAEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERAFTTRQRAI", "length": 210, "header": "tr|A0AC58HC89-1|A0AC58HC89_DANRE Computationally mapped isoform of Uncharacterized protein isoform X10 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=1 CANONICAL=A0A8M9PIF9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HC97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9/entry#A0AC58HC97-1", "sequence": { "sequence": "MSRPPDRAKQEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERAFTTRQRAI", "length": 209, "header": "tr|A0AC58HC97-1|A0AC58HC97_DANRE Computationally mapped isoform of Uncharacterized protein isoform X12 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=1 CANONICAL=A0A8M9PIF9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HCA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9/entry#A0AC58HCA4-1", "sequence": { "sequence": "MSRPPDRAKQAEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERDAPRHSSTIQPGQITISDDEDLDPPETGPENTSCYSKYTDLYLPNVEQENEEPVAVNVNNFQHTAMEETDITLPDIVANLSLPIDHKMVSRFNISRANVWDGAVRGFKRTTYSETCDMLVKFTDDTGVLEEGLDTGGPRREFLTLLMKHLKDRPIFDGPEGH", "length": 363, "header": "tr|A0AC58HCA4-1|A0AC58HCA4_DANRE Computationally mapped isoform of Uncharacterized protein isoform X4 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=1 CANONICAL=A0A8M9PIF9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HCA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9/entry#A0AC58HCA6-1", "sequence": { "sequence": "MSRPPDRAKQAEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERDAPRHSSTIQPGQITISDDEDLDPPETGPENTSCYREETDITLPDIVANLSLPIDHKMVSRFNISRANVWDGAVRGFKRTTYSETCDMLVKFTDDTGVLEEGLDTGGPRREFLTLLMKHLKDRPIFDGPEGH", "length": 333, "header": "tr|A0AC58HCA6-1|A0AC58HCA6_DANRE Computationally mapped isoform of Uncharacterized protein isoform X6 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=1 CANONICAL=A0A8M9PIF9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HCA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9/entry#A0AC58HCA9-1", "sequence": { "sequence": "MFCPFCGKHMSTLTRFCFTFGRCFEFLKDADQTETPGMSRPPDRAKQEQPCPSYKRFMEYRNLKSNDWQSCNYGPKGRYKPKERKQVQINVGVMVPHGSDLKPLRGKTLPLFTDPDVAAPDLLKHAVEKIRTFNKDMPEGPYVLLYPDCSEVDYVPGSDRPFKLSEYKKEIGKAYARIPFFICLEKHYKRVDDTSDSDFDSEIVITTRSTAEFNQADTLVFEPQNQSTPKLKLEDERDAPRHSSTIQPGQITISDDEDLDPPETGPENTSCYREETDITLPDIVANLSLPIDHKMVSRFNISRANVWDGAVRGFKRTTYSETCDMLVKFTDDTGVLEEGLDTGGPRREFLTLLMKHLKDRPIFDGPEGH", "length": 369, "header": "tr|A0AC58HCA9-1|A0AC58HCA9_DANRE Computationally mapped isoform of Uncharacterized protein isoform X7 OS=Danio rerio OX=7955 GN=LOC103908824 PE=4 SV=1 CANONICAL=A0A8M9PIF9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103908824", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103908824", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PIF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIF9" }, { "id": "PS50237", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50237" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HECT", "eco_id": "ECO_0000259", "start_pos": 356, "end_pos": 388, "start_aa": "Met", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 331, "end_pos": 333 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9NYR9-1", "uniprot_ac": "A0A8M9NYR9", "uniprot_id": "A0A8M9NYR9_DANRE", "mass": { "chemical_mass": 124670.0, "monoisotopic_mass": 124670.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110437818", "type": "recommended", "evidence": [ { "id": "A0A8M9NYR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYR9" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9NYR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYR9/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NYR9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYR9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110437818", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYR9", "locus": {} } ], "crossref": [ { "id": "A0A8M9NYR9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9NYR9", "database": "AlphaFoldDB", "categories": [] }, { 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"categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110437818", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437818", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9NYR9", "url": "https://www.orthodb.org/?gene=A0A8M9NYR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322162", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9NYR9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9NYR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HDT5", "url": "https://www.uniprot.org/uniprotkb/A0AC58HDT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HDT5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HDT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVNEVVQIRFCFIMDDTQISRDENVSPGCSSVHQKRSDPEPSCVSMRSDQSRDLPYNFKSEDTPTDLSLFHHKRTEAESSRVSMRSDTFMNHPVNMGNGEAQCNIRQNLLNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEIFSDKYKVLFIFDGLDECRLPLNFKRNETLRDVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRIRDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNVNEFDQINKQSLWFKVKDLFQLNSSECVSLSELHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQRLLTLKSRSIQKIKTVEYIKKKIRKIDSPERSLNLFHCLNELGDHSLVEEIQQYLKSGRIKQSKLSSSQWSAVVFVLLTSENKLDKFDINEFVGESTKAEKLKILQKLLPVIKVHLRDCGLTDEDSDVLTSALRSNPVHLGFLSLSYKKLKDSGIKLLSAVLEDPHCKLKTLWLSYCGLTDEGCAALASALRSNPEHLRELDLSGNKLGDSVTLLSAVLEDPRCKLKTLWLRYCGLTDEGFAALASALRSNPEHLRDLYLSVNNLGDSMTLLSAVLEDPHCKLEKLGLIDCGLTDEGCAALASALRSNLEHLRDLDLSGNNLGDSVTLLSAVLEDPRCKLKTLWLSNCGLTDEGCAALDSALRSNREHLRYLNVSGNKLGDSVTLLSAVLEDPHYKLKTLWLSNCGLTDEGCAALASALRSNPEHLRDLNLSENKLGDSVTLLSAVLEDPHCKLERLGLSDCALTDEGCAALASALRLNPKHLRDLNLSRNKLSKFTVKLFSDLKDDPHNKLETLYI", "length": 1106, "header": "tr|A0A8M9NYR9-1|A0A8M9NYR9_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=LOC110437818 PE=4 SV=2 CANONICAL=A0A8M9NYR9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9NYR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYR9/entry#A0A8M9NYR9-1", "sequence": { "sequence": 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"length": 1106, "header": "tr|A0A8M9NYR9-1|A0A8M9NYR9_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=LOC110437818 PE=4 SV=2 CANONICAL=A0A8M9NYR9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HDT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYR9/entry#A0AC58HDT5-1", "sequence": { "sequence": "MVNEVVQIRFCFIMDDTQISRDENVSPGCSSVHQKRSDPEPSCVSMRSDQSRDLPYNFKSEDTPTDLSLFHHKRTEAESSRVSMRSDTFMNHPVNMGNGEAQCNIRQNLLNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEIFSDKYKVLFIFDGLDECRLPLNFKRNETLRDVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRIRDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNVNEFDQINKQSLWFKVKDLFQLNSSECVSLSELHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQRLLTLKSRSIQKIKTVEYIKKKIRKIDSPERSLNLFHCLNELGDHSLVEEIQQYLKSGRIKQSKLSSSQWSAVVFVLLTSENKLDKFDINEFVGESTKAEKLKILQKLLPVIKVHLRDCGLTDEDSDVLTSALRSNPVHLGFLSLSYKKLKDSGIKLLSAVLEDPHCKLKTLWLSYCGLTDEGCAALASALRSNPEHLRELDLSGNKLGDSVTLLSAVLEDPRCKLKTLWLRYCGLTDEGFAALASALRSNPEHLRDLYLSVNNLGDSMTLLSAVLEDPHCKLEKLGLIDCGLTDEGCAALASALRSNLEHLRDLDLSGNNLGDSVTLLSAVLEDPRCKLKTLWLSNCGLTDEGCAALDSALRSNREHLRYLNVSGNKLGDSVTLLSAVLEDPHYKLKTLWLSDCALTDEGCAALASALRLNPKHLRDLNLSRNKLSKFTVKLFSDLKDDPHNKLETLYI", "length": 1049, "header": "tr|A0AC58HDT5-1|A0AC58HDT5_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X2 OS=Danio rerio OX=7955 GN=LOC110437818 PE=4 SV=1 CANONICAL=A0A8M9NYR9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110437818", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437818", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NYR9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYR9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NYR9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYR9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1019, "end_pos": 1021, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1076, "end_pos": 1078, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 962, "end_pos": 964, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9NYR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYR9" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 194, "end_pos": 327, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1019, "end_pos": 1021 }, { "start_pos": 1076, "end_pos": 1078 }, { "start_pos": 24, "end_pos": 26 }, { "start_pos": 289, "end_pos": 291 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 962, "end_pos": 964 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9NYS8-1", "uniprot_ac": "A0A8M9NYS8", "uniprot_id": "A0A8M9NYS8_DANRE", "mass": { "chemical_mass": 22759.0, "monoisotopic_mass": 22759.0 }, "refseq": { "ac": "XP_021322177", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322177" }, "gene_names": [ { "name": "LOC110437927", "type": "recommended", "evidence": [ { "id": "A0A8M9NYS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYS8" } ] }, { "name": "LOC110437927", "type": "synonym", "evidence": [ { "id": "XP_021322177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322177" } ] } ], "protein_names": [ { "name": "C-type lectin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9NYS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYS8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021322177", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322177" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322177.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322177", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322177" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NYS8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYS8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110437927", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYS8", "locus": {} } ], "crossref": [ { "id": "A0A8M9NYS8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9NYS8", "database": "AlphaFoldDB", "categories": [] }, { "id": "110437927", "url": "https://www.ncbi.nlm.nih.gov/gene/110437927", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110437927", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437927", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9NYS8", "url": "https://www.orthodb.org/?gene=A0A8M9NYS8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784:SF3", "database": "PANTHER", "categories": [ "Protein 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"annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9NYS8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYS8" }, { "id": "PF00059", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 125, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 87, "end_pos": 89 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9NYX3-1", "uniprot_ac": "A0A8M9NYX3", "uniprot_id": "A0A8M9NYX3_DANRE", "mass": { "chemical_mass": 30041.0, "monoisotopic_mass": 30041.0 }, "refseq": { "ac": "XP_021322222", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322222" }, "gene_names": [ { "name": "LOC110437941", "type": "recommended", "evidence": [ { "id": "A0A8M9NYX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYX3" } ] }, { "name": "LOC110437941", "type": "synonym", "evidence": [ { "id": "XP_021322222", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322222" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9NYX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYX3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021322222", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322222" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322222", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322222" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NYX3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYX3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110437941", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYX3", "locus": {} } ], "crossref": [ { "id": "A0A8M9NYX3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9NYX3", "database": "AlphaFoldDB", "categories": [] }, { "id": "110437941", "url": "https://www.ncbi.nlm.nih.gov/gene/110437941", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040958", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040958", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110437941", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437941", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9NYX3", "url": "https://www.orthodb.org/?gene=A0A8M9NYX3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF18744", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18744", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322222", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322222", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9NYX3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYX3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9NYX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYX3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKFTLFLNGLLLLFLLPNWTESVEEEGMKDESAEEESVKGQSVKSVDINTLARIINFFEQNYKRVDPDGHVRQYATAINVPVEQCQPDFDLDQNNFLTQETPAIVKNNITDETNALYQGAELIAAGTRKVVITKNKQYNRHSESLLLNPVGNSPMTKLLNKRKDGCSVFYTFESPCVDTCLNPDSKHNILGGLMKWKEHGGIKAFVFKNFWKFDTGKDLQSEFRKIAAIVPLYRCESANECIACKGEGDTAIDSRCLPSNMKKNEL", "length": 266, "header": "tr|A0A8M9NYX3-1|A0A8M9NYX3_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC110437941 PE=4 SV=1 CANONICAL=A0A8M9NYX3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9NYX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NYX3/entry#A0A8M9NYX3-1", "sequence": { "sequence": "MKFTLFLNGLLLLFLLPNWTESVEEEGMKDESAEEESVKGQSVKSVDINTLARIINFFEQNYKRVDPDGHVRQYATAINVPVEQCQPDFDLDQNNFLTQETPAIVKNNITDETNALYQGAELIAAGTRKVVITKNKQYNRHSESLLLNPVGNSPMTKLLNKRKDGCSVFYTFESPCVDTCLNPDSKHNILGGLMKWKEHGGIKAFVFKNFWKFDTGKDLQSEFRKIAAIVPLYRCESANECIACKGEGDTAIDSRCLPSNMKKNEL", "length": 266, "header": "tr|A0A8M9NYX3-1|A0A8M9NYX3_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC110437941 PE=4 SV=1 CANONICAL=A0A8M9NYX3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110437941", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437941", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 18, "end_pos": 20 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9NZG4-1", "uniprot_ac": "A0A8M9NZG4", "uniprot_id": "A0A8M9NZG4_DANRE", "mass": { "chemical_mass": 120264.0, "monoisotopic_mass": 120264.0 }, "refseq": { "ac": "XP_021322467", "name": "thrombospondin type-1 domain-containing protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322467" }, "gene_names": [ { "name": "adamtsl4", "type": "recommended", "evidence": [ { "id": "A0A8M9NZG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZG4" } ] }, { "name": "adamtsl4", "type": "synonym", "evidence": [ { "id": "XP_021322467", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322467" } ] } ], "protein_names": [ { "name": "Thrombospondin type-1 domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "A0A8M9NZG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZG4/entry#names_and_taxonomy" } ] }, { "name": "thrombospondin type-1 domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "XP_021322467", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322467" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322467.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322467" } ] } ], "disease": [ { "disease_id": "DOID:0111149", "recommended_name": { "id": "DOID:0111149", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111149", "name": "autosomal recessive isolated ectopia lentis 2", "description": "An isolated ectopia lentis that has_material_basis_in homozygous or compound heterozygous mutation in the ADAMTSL4 gene on chromosome 1q21." }, "synonyms": [ { "id": "DOID:0111149", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111149", "name": "ECTOL2", "description": "" }, { "id": "MONDO:0009152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009152", "name": "ectopia lentis 2, isolated, autosomal recessive", "description": "An isolated ectopia lentis that has material basis in homozygous or compound heterozygous mutation in the ADAMTSL4 gene on chromosome 1q21." }, { "id": "MONDO:0009152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009152", "name": "ECTOL2", "description": "" }, { "id": "MONDO:0009152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009152", "name": "ectopia lentis 2, isolated, autosomal recessive", "description": "" }, { "id": "MONDO:0009152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009152", "name": "ectopia lentis, isolated, autosomal recessive", "description": "" }, { "id": "MONDO:0009152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009152", "name": "autosomal recessive isolated ectopia lentis", "description": "" }, { "id": "MONDO:0009152", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009152", "name": "ectopia lentis, isolated autosomal recessive", "description": "" }, { "id": "MIM:225100", "resource": "MIM", "url": "https://www.omim.org/entry/225100", "name": "Ectopia lentis 2, isolated, autosomal recessive", "description": "Ectopia lentis 2, isolated, autosomal recessive" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111149", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111149" } ] }, { "disease_id": "DOID:0111648", "recommended_name": { "id": "DOID:0111648", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111648", "name": "ectopia lentis with ectopia of pupil", "description": "An eye disease characterized by displacement of the lenses and the pupils in association with other ocular anomalies that has_material_basis_in homozygous or compound heterozygous mutation mutation in the ADAMTSL4 gene on chromosome 1q21.2." }, "synonyms": [ { "id": "DOID:0111648", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111648", "name": "ectopia lentis et pupillae", "description": "" }, { "id": "MONDO:0009153", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009153", "name": "ectopia lentis et pupillae", "description": "" }, { "id": "MONDO:0009153", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009153", "name": "ectopia lentis et pupillae", "description": "" }, { "id": "MIM:225200", "resource": "MIM", "url": "https://www.omim.org/entry/225200", "name": "Ectopia lentis et pupillae", "description": "Ectopia lentis et pupillae" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111648", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111648" } ] }, { "disease_id": "DOID:110", "recommended_name": { "id": "DOID:110", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:110", "name": "lens disease", "description": "An eye disease that affects the lens of the eye, which is the transparent disc that focuses light to the photosensors in the back of the eye." }, "synonyms": [], "unlinked_id_list": [ "DOID:0111148" ], "evidence": [ { "id": "110", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:110" } ] }, { "disease_id": "DOID:2340", "recommended_name": { "id": "DOID:2340", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2340", "name": "craniosynostosis", "description": "A synostosis that results_in premature fusion located_in skull." }, "synonyms": [ { "id": "DOID:2340", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2340", "name": "Premature closure of cranial sutures", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Shprintzen-Goldberg syndrome", "description": "Shprintzen-Goldberg syndrome (SGS) is a very rare genetic disorder characterized by craniosynostosis, craniofacial and skeletal abnormalities, marfanoid habitus, cardiac anomalies, neurological abnormalities, and intellectual disability." }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Marfanoid craniosynostosis syndrome", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "SGS", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Shprintzen Goldberg Syndrome", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Shprintzen-Goldberg syndrome", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Marfanoid disorder with craniosynostosis type 1", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Marfanoid-craniosynostosis syndrome", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Shprintzen-Goldberg craniosynostosis syndrome", "description": "" }, { "id": "MONDO:0008426", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008426", "name": "Shprintzen-Goldberg marfanoid syndrome", "description": "" }, { "id": "MONDO:0010903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010903", "name": "craniosynostosis, Adelaide type", "description": "" }, { "id": "MONDO:0010903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010903", "name": "craniosynostosis, Adelaide type", "description": "" }, { "id": "MONDO:0010903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010903", "name": "CRSA", "description": "" }, { "id": "MIM:182212", "resource": "MIM", "url": "https://www.omim.org/entry/182212", "name": "Shprintzen-Goldberg craniosynostosis syndrome", "description": "Shprintzen-Goldberg craniosynostosis syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "2340", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2340" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZG4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "adamtsl4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZG4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070815-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070815-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9NZG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9NZG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100333903", "url": "https://www.ncbi.nlm.nih.gov/gene/100333903", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045371", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045371", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050439", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050439", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100333903", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333903", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PRYPGQH", "url": "https://omabrowser.org/oma/group/PRYPGQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9NZG4", "url": "https://www.orthodb.org/?gene=A0A8M9NZG4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13723:SF312", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13723:SF312", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05986", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05986", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19236", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19236", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322467", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9NZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9NZG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070815-2", "url": "https://zfin.org/ZDB-GENE-070815-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRSGSQSRLCVFWCCVLAVLPLTTADEAEKPAAGRQSRQAEEVGLEGVWAPWSEWVECSQSCGVGVAERRRQCMPPPQTPPLTWNRPSYLPPGVPNNTPVISAVRPFYNNLYPPNEPYGAERPFPPALPANQNPGLPLYRNEGGQFGSSGQEPVSVYRSPSSSSSLPYSRVPARTPSHGRGGAIGSRRAVSTNRDPASVRRSSSSIRPGQFGYGRVPFSLPLHRQNRHARHTHHNTSTDSLDALNVNSSSHGEKTHEKTPADKVSEDNDDGEQRRRVRIPHIRPPAQRNGARDRRIEGRTSRQAPPSYTRTISRTHTSRDPPPYGPQTPSNPNPEPWAPVQTPGNEQDWRPPVAGNYRCSGRDREYRRCSLQACPGAAVNSRADQCSAFNAQEFMGRVYDWEPFTEVGLEQQCELTCRPVGYRFYVRQAERVRDGTPCANNTPTDVCVGGRCLSEGCDGVLGSGLVRDRCGVCGGEDGTCERVSGSFMNTSVPLGYHKILDIPPGATAINITERRASPNYLALRSGTGQSVVNGRWAVDPPGEYQAGGAAFLYTRPKAEPQEPGEDRGETLTAAGPTTALLQLYIIFHRQNPGIDYEYYIPVDKRRDGETEVLRERERGRSALRETTGVSMAVENPVAPPPVSSSFPSSSSSSSSSSDRWPPERPRPQGLGPNRNARIPPRTDLPLDNLPVFVWRRGALTECTATCGKGSQYREIVCVNRHTEQEVHERRCDSATKPTPEEEPCNVHPCPPFWDMGAWSECSVSCGWGVQQRQIQCRQSFGNRSTMVHPQRCAGLSRPNATQPCHPRVCSHWEISTNWSTCSVDCGMGKRTRNVRCVSNHGNTVNDRECNDRLRPQHSEDCHMGPCVTNWYFTDWTHTCSAECGPGVQRREVVCVSAGGRREGDGGLECVGDKPADMKACNGGPCTATYLWYTGPWGYCNAVCGNGTQRRDVICVRKSGSEFTVSSSSDCSHLEKPSPVQPCELQPCTPQWFTTDWSTCSRSCGEGLQTREVRCLTPDKQHSATCHPDARPAHQQPCNTIPCSPFEDENCKDRRHNCVMVVQARLCVYSYYKTACCASCTQSAQRAKRH", "length": 1089, "header": "tr|A0A8M9NZG4-1|A0A8M9NZG4_DANRE Isoform 1 of Thrombospondin type-1 domain-containing protein 4 OS=Danio rerio OX=7955 GN=adamtsl4 PE=4 SV=2 CANONICAL=A0A8M9NZG4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9NZG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZG4/entry#A0A8M9NZG4-1", "sequence": { "sequence": "MRSGSQSRLCVFWCCVLAVLPLTTADEAEKPAAGRQSRQAEEVGLEGVWAPWSEWVECSQSCGVGVAERRRQCMPPPQTPPLTWNRPSYLPPGVPNNTPVISAVRPFYNNLYPPNEPYGAERPFPPALPANQNPGLPLYRNEGGQFGSSGQEPVSVYRSPSSSSSLPYSRVPARTPSHGRGGAIGSRRAVSTNRDPASVRRSSSSIRPGQFGYGRVPFSLPLHRQNRHARHTHHNTSTDSLDALNVNSSSHGEKTHEKTPADKVSEDNDDGEQRRRVRIPHIRPPAQRNGARDRRIEGRTSRQAPPSYTRTISRTHTSRDPPPYGPQTPSNPNPEPWAPVQTPGNEQDWRPPVAGNYRCSGRDREYRRCSLQACPGAAVNSRADQCSAFNAQEFMGRVYDWEPFTEVGLEQQCELTCRPVGYRFYVRQAERVRDGTPCANNTPTDVCVGGRCLSEGCDGVLGSGLVRDRCGVCGGEDGTCERVSGSFMNTSVPLGYHKILDIPPGATAINITERRASPNYLALRSGTGQSVVNGRWAVDPPGEYQAGGAAFLYTRPKAEPQEPGEDRGETLTAAGPTTALLQLYIIFHRQNPGIDYEYYIPVDKRRDGETEVLRERERGRSALRETTGVSMAVENPVAPPPVSSSFPSSSSSSSSSSDRWPPERPRPQGLGPNRNARIPPRTDLPLDNLPVFVWRRGALTECTATCGKGSQYREIVCVNRHTEQEVHERRCDSATKPTPEEEPCNVHPCPPFWDMGAWSECSVSCGWGVQQRQIQCRQSFGNRSTMVHPQRCAGLSRPNATQPCHPRVCSHWEISTNWSTCSVDCGMGKRTRNVRCVSNHGNTVNDRECNDRLRPQHSEDCHMGPCVTNWYFTDWTHTCSAECGPGVQRREVVCVSAGGRREGDGGLECVGDKPADMKACNGGPCTATYLWYTGPWGYCNAVCGNGTQRRDVICVRKSGSEFTVSSSSDCSHLEKPSPVQPCELQPCTPQWFTTDWSTCSRSCGEGLQTREVRCLTPDKQHSATCHPDARPAHQQPCNTIPCSPFEDENCKDRRHNCVMVVQARLCVYSYYKTACCASCTQSAQRAKRH", "length": 1089, "header": "tr|A0A8M9NZG4-1|A0A8M9NZG4_DANRE Isoform 1 of Thrombospondin type-1 domain-containing protein 4 OS=Danio rerio OX=7955 GN=adamtsl4 PE=4 SV=2 CANONICAL=A0A8M9NZG4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 577, "start_aa": "Thr", "end_pos": 577, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr577", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 738, "start_aa": "Thr", "end_pos": 738, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr738", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100333903", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333903", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AN95-1", "protein_name": "Thrombospondin type-1 domain-containing protein 4", "gene_name": "Thsd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSHLTSCLSALGALLLLGSQLVCPQPSTEHRKVPQRMAVAEGTPEDSGGGSPGVWGSWGPWSACSRSCSGGVMEQTRPCLPSSYRAPAGSRPSGPTLSITGHVVSAVRTSVPLHRSHEEQRTLAGSSASRQGPTVVRGSRHPQARSREPSERRSRTRGPIGPGKYGYGKAPYILPLQTDTTHTPQRLRRQRPSSRPSRSQEASASKQGYRPPTHHFSHNRPLYQSDSGPRSGLPPSEASIYQLPLTHDQNYPAASSLFHSPELSSNNGARPHGTSQAFSQHLRSTAISCIGAYRQYKLCNTNACPDSGRSIREVQCASYNNKPFMGRFYEWEPFAEVKGNRKCELNCQATGYRFYVRQAERVIDGTPCDQNGTAICVSGQCKSIGCDDFLGSDKVVDKCGVCGGDNTGCQVVSGVFKHALTSLGYHRVVEIPQGATKINITEMHKSNNYLALRSRSGRSIINGNWAIDRPGKYEGGGTMFTYKRPNEISSTAGESFLAEGPTNEILDVYMIHQQPNPGVHYEYVIMGNNAISPQVPPHRRPGEPFNGQLETEDGGQEDREEREKNQEKEDSHVEAPEVFTSESTQTFPVRHPERFPSHRPDNLVPPAPQHPRRNRDHNWKQLGTTECSTTCGKGSQYPIFRCVHRNTHEEVPESYCDSSMKPTPEEEPCNLFPCPAFWDIGEWSECSKTCGLGMQHRQVLCRQVYANRSLTVQPYRCQHLEKPETTSTCQLKICSEWQTRTDWTSCSVPCGVGQRTRDVKCVSNIGDVVDDEECNMKLRPNDIENCDMGPCAKSWFLTEWSERCSAECGAGVRTRSVVCMTNHISSLPLEGCGNNRPAEATPCDNGPCTGKVEWFTGSWSQCSVECGSGTQQREVICVRKNADTFEVLDPYECSFLEKPPSQQACHLKPCGAKWFSTEWSMCSKSCQGGFRVREVRCLSDDMTPGSLCDPQLKPEERESCNPQDCVPEVDENCKDKYYNCNVVVQARLCVYNYYKTACCASCTRVANRHTGFLGSR", "length": 1017 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070815-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070815-2#orthology", "database": "AGR" }, { "id": "RGD:1566296", "url": "https://alliancegenome.org/gene/RGD:1566296#orthology", "database": "AGR" }, { "id": "FB:FBgn0032252", "url": "https://alliancegenome.org/gene/FB:FBgn0032252#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M6YZ16-1", "protein_name": "Thrombospondin type-1 domain-containing protein 4 isoform X2", "gene_name": "adamtsl7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKEQKMGGHRWRLILHFLQMTLLLFFLCPPTEPAPWDSDSSSGPGEGCEGFQVDVCGVCAGDGSSCELFNGTIFLSVLSVRYHKILDIPSGALRIKIQETHKTRNYLALSMATGESVINGDWVIDRPGQFYAAGTQFTYKRPNEIRSRAGESITAPGPTNQELNLFVIYQQPDAAVYYEYILPKHTNTHSDAYSYSSVLPLVESHGIFPDSENSVGENSLSSFHPNQVPSDSVTLEPVPLYSWMAMATTPCSTTCGTGNRQVLFGCVERATQTTVLEDLCSSITHPGPQVEECQSQPCPAFWDVGEWSECSKTCGPGFQYRQVICRQTQGQHGSSTVVVANSMCDDTEMPDTTSVCQLKICSEWQIRSEWTECSVPCGVGQRSREVVCVDNLGDIVSDEECNMALRPQDLQNCDKGVCASSWFYSLWSERCSADCAEGSRSRSVVCLMSQSNSLPLDDCDDEDKPDELMQCDLGPCTQRLEWYTGPWGQCSSECGNGTQSRGVVCVVQNGGHLEVTSDDLCSHLPRPPTAQSCYLKSCAAQWFMTEWSSCSRSCEGGFRVREVRCLRDDLTSSHDCDPALEPAKQEKCNTHICTLQIDESCRDMYYNCVVVVQARLCVYSYYRTTCCASCSRVIQRDSLHTIR", "length": 643 }, "evidence": [ { "id": "FB:FBgn0032252", "url": "https://alliancegenome.org/gene/FB:FBgn0032252#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1MXR3-1", "protein_name": "ADAMTS like 4", "gene_name": "ADAMTSL4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEKWAGRPQLCLMLLLSLPQLCLDQEVLSGHSLQTPPEESQGPEGVWGPWDQWASCSQPCGVGVQRRSRTCQLPTTQLHQGLPLPPRPPRHPEALLPRGQGTRPQTSRETLPLYRPPPRGRGGPLRGPASQLGREEAPETQGARRSRVRDPIKPGMFGYGRVPFALPLHRNRRHPRRPPRSELSQTSDLPSLTPRTEPSSSNHTQKTELSPTEPSAHTLPPQAEPPSPEAAQTAVPSRARPAPTGPHPRAQASGTESSFHSPSPGEGSSFHLSLQPRRPSSQGWASPRLADRHPNPFLSVPWGRGQQSQEQWRPGGNLHGSLTESAPPQPDGWLPLLSSGPHSSPLWSLFAPSSPVPRCSGESEQLRACSQAPCPAEQPDPRALQCAAFDSQEFMGQLYQWEPFTEVQGSQRCELNCRPRGFRFYVRHTQKVQDGTLCQPGSLDICVAGRCLSPGCDGILGSGRHPDGCGVCGGDDSTCRLVLGNLTERGGPLGYQKILSIPAGASRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDPPGSYTAGGTVFRYNRPPREEGAGESLSAEGPTTQPVDVYMIFQEENPGVFYQYVISSPPPNLENPTPEPRVPQLQPEILRVEPPPVSAPRPARTPGTLQRQVRIPQMPAPPPPRTPLGSPAGYWKRVGHSECSASCGKGVWRPIFLCISRESGEELDERSCAMGARPPASQEPCHGPPCPPYWEAGEWTSCSRSCGPGTQHRQLRCRQEFGGGGSSVPLERCGHLPRPNITQPCQLRLCGHWEVRSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPRPPSREACDMGPCTTAWFHSDWSSKCSAECGTGIQRRSVVCLGSGEAHGISQEEAGAGAGEQTCAPGSRPPDMRACSLGPCEVSWCWYTGPWAECSSECGSGTQRRDVICVSKLGTEFNVTSPSNCSHLPRPPALQPCQGQDCQDRWFSTPWSPCSRSCQGGVQTREVQCLTANQTLSIRCPLHLRPARKRSCNSQPCSQRPDDQCKDSSPHCPLVVQARLCVYPYYTATCCRSCAHVLERSSPEPA", "length": 1070 }, "evidence": [ { "id": "A0A8M9NZG4", "url": "https://omabrowser.org/oma/group/A0A8M9NZG4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3UTY6-1", "protein_name": "Thrombospondin type-1 domain-containing protein 4", "gene_name": "Thsd4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSYLTSCLSALSTLLLLLGSQLVCPQPSTEHRKVPQRMAVTEGTPEDSGSGSPGVWGSWGPWSACSRSCSGGVMEQTRPCLPSSYRARGGSRPNGRALSITGHVVSAVRTSVPLHRSQEDQRALAGSNASRQGPAVVRGSRHPQARGREPSERRSRTRGPIGPGKYGYGKAPYILPLQTDTTHTPQRLRRQRPSSRHSRSQEASASKQGYRPPTHQFSHSQPLYQSDSGPRSGLPPSEASIYQLPLTHDQSYPAASSLFHRPELSSHHGARPHGAAQAFPQHLRSTAISCIGAYRQYKLCNTNACPESGRSIREVQCASYNNKPFMGRFYEWEPFAEVKGNRKCELNCQATGYRFYVRQAEKVIDGTPCDQNGTAICVSGQCKSIGCDDFLGSDKVLDKCGVCGGDNTGCQVVSGVFKHALTSLGYHRVVEIPQGATKINITEMHKSNNYLALRSRSGRSIINGNWAIDRPGKYEGGGTMFTYKRPNEVSSTAGESFLAEGPTNEILDVYMIHQQPNPGVHYEYVIMRNNAISPQVPPHRRPGEPFNGQLEEEDRGQEDREEREKNQEKEDSQVEAPEVFTSESTQTFPVRHPERFPSHRPDNLVPPAPQPPRRSRDHNWKQLGTTECSTTCGKGSQYPIFRCVHRNTHEEVPESYCDSSMKPTPEEEPCNLFPCPAFWDIGEWSECSKTCGLGMQHRQVLCRQVYANRSLTVQPYRCQHLEKPETTSTCQLKICSEWQIRTDWTSCSVPCGVGQRTRDVKCVSNIGDMVHDEECNMKLRPNDIENCDMGPCAKSWFLTEWSERCSAECGAGVRTRSVVCMTNHVSSLPLEGCGNNRPVEATPCDNGPCTGKVEWFTGSWSQCSIECGSGTQQREVICVRKNADTFEVLDPYECSFLEKPPSQQACHLKPCGAKWFSTEWSMCSKSCQGGFRVREVRCLSDDMTPSSLCDPQLKPEERESCNTQDCVPEVDENCKDKYYNCNVVVQARLCVYNYYKTACCASCTRVANRHVGFLGSR", "length": 1018 }, "evidence": [ { "id": "RGD:1566296", "url": "https://alliancegenome.org/gene/RGD:1566296#orthology", "database": "AGR" }, { "id": "FB:FBgn0032252", "url": "https://alliancegenome.org/gene/FB:FBgn0032252#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4FZU4-1", "protein_name": "ADAMTS-like protein 4", "gene_name": "Adamtsl4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELWLGRLWLYVMLLLLLLQLCQDQELLGPSLQTPSEEDQVPEGLWGPWGRWASCSQPCGVGVQRRSRTCELHPALSLPPRPPRHPEAPQPRGQGSRPQTPRDPQSLYRPQPRGRGGPLRGPASQVGREETQEPRGAQRFRVRDPIKPGMFGYGRVPFALPLHRSRRLAHKPGQPKDSSTAEETLPSQPPSTEPASEKHSPHMQPPELRAQSRSPSAETPRSGTAQTEVPSRTSSAPSDMGIPAPTSSFRDSRSFQGSPEPRMPTSQGAERQPHPFSPVTRSQLSRRHWRPPGSPHRSPDGWLPLTRDSSPHWSLFAPSSPTPECSGESEQMRACSQEPCPPEQPDPRALQCAAFDSQEFMGQLYQWEPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGSLDICVAGHCLSPGCDGILGSGRRPDGCGVCGGDGSTCRLVSGNLTDRGGPLGYQKILWIPAGASHLRISQFRPSSNYLALRGPGGRSIINGNWAVDPPGSYAAVGTVFQYNRPPREEGKGETLSAEGPTTQPVDVYMIFQEDNPGVFYQYVTSAAPESPSTMPPALQLQPEMLRGEPLLPSAPRPVRAPGTLQRQARIPQVPPPTHVRTAMGSSAGYWKQVGHSECSASCGKGVWRPIFLCVSRESGEELDEQSCAVGARPPASPESCHRPPCPPYWEAGEWTSCSRSCGPGTQHRQLLCRQEFGGGGSSVPPERCGHLPRPNITQSCQLRLCGHWEISSPWSQCSVRCGRGQRSRQVRCVGSNGHEVGKQECASGPPPPPSREACDMGPCTTAWFYSDWSSKCSAECGTGIQRRAVVCLRSGETLQGDPEAGSTEQGCPLRSRPPDMRACSLGPCEKTWRWYTGPWSECSSECGSGTQHRDIICVSKLGTKFNVTSPSNCSHLPRPPALQPCQGQACEDQWFSTLWSPCSQSCQGGVQTREVQCLSSNHTLSSRCPPHLRPSRKRPCNSQPCNQRPDDQCKDSSPHCPLVVQARLCVYPYYTATCCRSCAHVLEQSQLEPA", "length": 1030 }, "evidence": [ { "id": "HGNC:19706", "url": "https://alliancegenome.org/gene/HGNC:19706#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070815-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070815-2#orthology", "database": "AGR" }, { "id": "MGI:2389008", "url": "https://alliancegenome.org/gene/MGI:2389008#orthology", "database": "AGR" }, { "id": "RGD:1561012", "url": "https://alliancegenome.org/gene/RGD:1561012#orthology", "database": "AGR" }, { "id": "FB:FBgn0032252", "url": "https://alliancegenome.org/gene/FB:FBgn0032252#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6UY14-1", "protein_name": "ADAMTS-like protein 4", "gene_name": "ADAMTSL4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENWTGRPWLYLLLLLSLPQLCLDQEVLSGHSLQTPTEEGQGPEGVWGPWVQWASCSQPCGVGVQRRSRTCQLPTVQLHPSLPLPPRPPRHPEALLPRGQGPRPQTSPETLPLYRTQSRGRGGPLRGPASHLGREETQEIRAARRSRLRDPIKPGMFGYGRVPFALPLHRNRRHPRSPPRSELSLISSRGEEAIPSPTPRAEPFSANGSPQTELPPTELSVHTPSPQAEPLSPETAQTEVAPRTRPAPLRHHPRAQASGTEPPSPTHSLGEGGFFRASPQPRRPSSQGWASPQVAGRRPDPFPSVPRGRGQQGQGPWGTGGTPHGPRLEPDPQHPGAWLPLLSNGPHASSLWSLFAPSSPIPRCSGESEQLRACSQAPCPPEQPDPRALQCAAFNSQEFMGQLYQWEPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGAPDICVAGRCLSPGCDGILGSGRRPDGCGVCGGDDSTCRLVSGNLTDRGGPLGYQKILWIPAGALRLQIAQLRPSSNYLALRGPGGRSIINGNWAVDPPGSYRAGGTVFRYNRPPREEGKGESLSAEGPTTQPVDVYMIFQEENPGVFYQYVISSPPPILENPTPEPPVPQLQPEILRVEPPLAPAPRPARTPGTLQRQVRIPQMPAPPHPRTPLGSPAAYWKRVGHSACSASCGKGVWRPIFLCISRESGEELDERSCAAGARPPASPEPCHGTPCPPYWEAGEWTSCSRSCGPGTQHRQLQCRQEFGGGGSSVPPERCGHLPRPNITQSCQLRLCGHWEVGSPWSQCSVRCGRGQRSRQVRCVGNNGDEVSEQECASGPPQPPSREACDMGPCTTAWFHSDWSSKCSAECGTGIQRRSVVCLGSGAALGPGQGEAGAGTGQSCPTGSRPPDMRACSLGPCERTWRWYTGPWGECSSECGSGTQRRDIICVSKLGTEFNVTSPSNCSHLPRPPALQPCQGQACQDRWFSTPWSPCSRSCQGGTQTREVQCLSTNQTLSTRCPPQLRPSRKRPCNSQPCSQRPDDQCKDSSPHCPLVVQARLCVYPYYTATCCRSCAHVLERSPQDPS", "length": 1074 }, "evidence": [ { "id": "HGNC:19706", "url": "https://alliancegenome.org/gene/HGNC:19706#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070815-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070815-2#orthology", "database": "AGR" }, { "id": "MGI:2389008", "url": "https://alliancegenome.org/gene/MGI:2389008#orthology", "database": "AGR" }, { "id": "RGD:1561012", "url": "https://alliancegenome.org/gene/RGD:1561012#orthology", "database": "AGR" }, { "id": "FB:FBgn0032252", "url": "https://alliancegenome.org/gene/FB:FBgn0032252#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6ZMP0-1", "protein_name": "Thrombospondin type-1 domain-containing protein 4", "gene_name": "THSD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSHFMGSLSVLCFLLLLGFQFVCPQPSTQHRKVPQRMAAEGAPEDDGGGGAPGVWGAWGPWSACSRSCSGGVMEQTRPCLPRSYRLRGGQRPGAPARAFADHVVSAVRTSVPLHRSRDETPALAGTDASRQGPTVLRGSRHPQPQGLEVTGDRRSRTRGTIGPGKYGYGKAPYILPLQTDTAHTPQRLRRQKLSSRHSRSQGASSARHGYSSPAHQVPQHGPLYQSDSGPRSGLQAAEAPIYQLPLTHDQGYPAASSLFHSPETSNNHGVGTHGATQSFSQPARSTAISCIGAYRQYKLCNTNVCPESSRSIREVQCASYNNKPFMGRFYEWEPFAEVKGNRKCELNCQAMGYRFYVRQAEKVIDGTPCDQNGTAICVSGQCKSIGCDDYLGSDKVVDKCGVCGGDNTGCQVVSGVFKHALTSLGYHRVVEIPEGATKINITEMYKSNNYLALRSRSGRSIINGNWAIDRPGKYEGGGTMFTYKRPNEISSTAGESFLAEGPTNEILDVYMIHQQPNPGVHYEYVIMGTNAISPQVPPHRRPGEPFNGQMVTEGRSQEEGEQKGRNEEKEDLRGEAPEMFTSESAQTFPVRHPDRFSPHRPDNLVPPAPQPPRRSRDHNWKQLGTTECSTTCGKGSQYPIFRCVHRSTHEEAPESYCDSSMKPTPEEEPCNIFPCPAFWDIGEWSECSKTCGLGMQHRQVLCRQVYANRSLTVQPYRCQHLEKPETTSTCQLKICSEWQIRTDWTSCSVPCGVGQRTRDVKCVSNIGDVVDDEECNMKLRPNDIENCDMGPCAKSWFLTEWSERCSAECGAGVRTRSVVCMTNHVSSLPLEGCGNNRPAEATPCDNGPCTGKVEWFAGSWSQCSIECGSGTQQREVICVRKNADTFEVLDPSECSFLEKPPSQQSCHLKPCGAKWFSTEWSMCSKSCQGGFRVREVRCLSDDMTLSNLCDPQLKPEERESCNPQDCVPEVDENCKDKYYNCNVVVQARLCVYNYYKTACCASCTRVANRQTGFLGSR", "length": 1018 }, "evidence": [ { "id": "RGD:1566296", "url": "https://alliancegenome.org/gene/RGD:1566296#orthology", "database": "AGR" }, { "id": "FB:FBgn0032252", "url": "https://alliancegenome.org/gene/FB:FBgn0032252#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80T21-1", "protein_name": "ADAMTS-like protein 4", "gene_name": "Adamtsl4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLGRLWLCMMLLLPLPQPCQDQELFGPSHQLPSEEGQVPEGLWGPWGRWASCSQPCGVGVQRRSRTCELHPALPLPPRPPRHPEAHRPRGQGSRPQTPRDPQSLYRPQPRGRGGPLRAPASQVGREETQEPQGAQRFRVRDPIKPGMFGYGRVPFALPLHRSRRHPHRPGQPKNSSTGEGMVPSQPPSTELASEKHGPHMQPPEPRSHSAETPRSGTAQTEVLPRTSSAPSYTGTPAPTSSFGDSRSFQGSLGPRMPPSPGSWSSPQGAERRHPPPFSPVPRSQQSRRHWRPPGPHRSPDGWLPLTRDSSPLWSIFAPSIPAPNCSGESEQMRACSQEPCPPEQPDPRALQCAAFDSQEFMGQLYQWEPFTEVQGSQRCELNCRPRGFRFYVRHTEKVQDGTLCQPGSLDICVAGRCLSPGCDGVLGSGRRPDGCGVCGGDGSTCRLVSGNLTDRGGPLGYQKILWIPAGASHLHISQLRPSSNYLALRGPGGRSIINGNWAVDPPGSYTAIGTVFQYNRPPREEGKGESLSAEGPTTQPVDVYMIFQEDNPGVFYQYVISSPPAVLESPSTKPPALQPQPEMLRGEPLLPSAPRPVRAPGTLQRQVRIPQVPPPTRVRTAMGSSAGYWKQVGHSECSASCGKGVWHPIFLCISRESGEELDEQSCAVGARPPASPEPCHGPPCPPYWEAGEWTSCSRSCGPGTQHRQLLCRQEFGGGGSSVPPERCGHLPRPNITQPCQLHLCGHWEISSPWSQCSVRCGRGQRSRQVRCVGSNGDEVDKQECASGPPPPPSREACDMGPCTTAWFYSDWSSKCSAECGTGIQRRAVVCLRSGETLQGDPEAGSTEQGCPLRSRPPDMRACSLGPCERTWRWFTGPWSECSSECGSGTQHRDIICVSKLGAEFNVTSPSNCSHLPRPPALQPCQGQACEDKWFSTLWSPCSRSCQGGMQTREVQCLSGNQTLSSRCPPHLRPSRKRPCNSQPCNQRPDDQCKDSSPHCPLVVQARLCVYPYYTTTCCRSCAHVLEQSQLEPA", "length": 1036 }, "evidence": [ { "id": "HGNC:19706", "url": "https://alliancegenome.org/gene/HGNC:19706#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070815-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070815-2#orthology", "database": "AGR" }, { "id": "MGI:2389008", "url": "https://alliancegenome.org/gene/MGI:2389008#orthology", "database": "AGR" }, { "id": "RGD:1561012", "url": "https://alliancegenome.org/gene/RGD:1561012#orthology", "database": "AGR" }, { "id": "FB:FBgn0032252", "url": "https://alliancegenome.org/gene/FB:FBgn0032252#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VKV3-1", "protein_name": "Lonely heart, isoform A", "gene_name": "loh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAKLLLIFSILTILATIHDSSFVQADLTTKERIKKHQDWLREHRKPKTKKKISINSYYELANLWHTRKDLSSPKQKPNNKEEYLENETTSKISNKSDEKVLKSSTIISLNATNPSTSTFKSVLETTTLPSVTTKDLFESGNVATTRQTPKVEEVFSSPNPPQEATSSTSKKAKKKVYPYPRWDKWSDWSSCSRSCGGGVKYQVRKCINRNLLTNNQLTSNACVGYFKRYQLCNDVPCDEQSPDFRASQCSAYNDKEFHGHRYRWEPYVKDDAECELNCMPFGMKSFATLNESVIDGTPCGHPAEYFRSQFWERAVCVDGACKAVQASGEIDGLYAHSGSVSCGGLLCRPVTGIFTRNPLPEHAYIHVTTLPVGASNISITELKNSINLLVLRTSNELAIFNGENTVSESGSYEAVGAVFDYHRIDGAEDSNGVTEWITSIGPIRDSLQLMVFTKSANNTGVKYEYMLPIVSESEENEMSLESSDGLLRSGMEDTSSSSSSRAGRKRIFNWKVIGFSSCTKSCGGGTQTPIIRCIRKNPLRYYSQRRCTHSVKPVLNENLLHCNTQPCPAYWRFDDWGECRCSSSGGLRRREVSCVQELASGLVIHVDKAACMEDQPPMQKQCECPKNRRRNLSRYRLSGPSESSSNSSQVKRSKIDGSDATAIWLVSDWNQYCSVTCGSGVEYRTVFCDRSKAGEQRCDPSTTPESRRPCEKPACELGDWFTGPWSSCNGDCFDLTRTREVLCIRSQLITEHSECTPELKPQSVEKCSHEEVEYCAARWHYSDWSECTKPCGGGTQRRSVRCLEYDIKMNALRESTHCRYTNREPIYRNCNVQACAEVPKTEVTPVCADKFSNCQWASQAKLCSYDYYRDNCCFSCTGGI", "length": 880 }, "evidence": [ { "id": "HGNC:19706", "url": "https://alliancegenome.org/gene/HGNC:19706#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070815-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070815-2#orthology", "database": "AGR" }, { "id": "MGI:2389008", "url": "https://alliancegenome.org/gene/MGI:2389008#orthology", "database": "AGR" }, { "id": "RGD:1561012", "url": "https://alliancegenome.org/gene/RGD:1561012#orthology", "database": "AGR" }, { "id": "RGD:1566296", "url": "https://alliancegenome.org/gene/RGD:1566296#orthology", "database": "AGR" }, { "id": "FB:FBgn0032252", "url": "https://alliancegenome.org/gene/FB:FBgn0032252#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZG4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "camera-type eye morphogenesis", "id": "GO:0048593", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048593", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZG4" } ], "pmid": "" }, { "name": "regulation of extracellular matrix assembly", "id": "GO:1901201", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901201", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZG4" } ], "pmid": "" }, { "name": "cell-cell junction maintenance", "id": "GO:0045217", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045217", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZG4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZG4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 782, "end_pos": 784, "annotation": "n_glycosylation_sequon" }, { "start_pos": 799, "end_pos": 801, "annotation": "n_glycosylation_sequon" }, { "start_pos": 817, "end_pos": 819, "annotation": "n_glycosylation_sequon" }, { "start_pos": 945, "end_pos": 947, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9NZG4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZG4" }, { "id": "PS50900", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50900" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PLAC", "eco_id": "ECO_0000259", "start_pos": 1046, "end_pos": 1083, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 577, 738 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 235, "end_pos": 237 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 440, "end_pos": 442 }, { "start_pos": 489, "end_pos": 491 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 782, "end_pos": 784 }, { "start_pos": 799, "end_pos": 801 }, { "start_pos": 817, "end_pos": 819 }, { "start_pos": 945, "end_pos": 947 }, { "start_pos": 96, 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"MKQVTKPTRNHSENHFVTSGRARQMPALDNLPEQYLTGHWPREQNQPQPACMTDKATQTPAIWTEDGGEANTHKRSASWGSADHLIEISKLRQQLQHSLKGSRSIVEKEEASQTQPKRISTSSSNTALSRPLICRVPSYSECVNQELENVFICDQWRREEETALEVRDGGRAPVPALHQMSCCSPAADTEKDCRLGSPLPEFSSSPKPNNSFMFKREPPEGCEKVKVFEDLMSPGFPIFSCPDRNKVNFIPSGSAFCPVKLLCSSLFPSDASLQKQTSEHCSIRKCLLLS", "length": 290, "header": "tr|A0A8M9NZW5-1|A0A8M9NZW5_DANRE Isoform 1 of Glucocorticoid-induced transcript 1 protein isoform X1 OS=Danio rerio OX=7955 GN=glcci1b PE=4 SV=1 CANONICAL=A0A8M9NZW5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9NZW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW5/entry#A0A8M9NZW5-1", "sequence": { "sequence": "MKQVTKPTRNHSENHFVTSGRARQMPALDNLPEQYLTGHWPREQNQPQPACMTDKATQTPAIWTEDGGEANTHKRSASWGSADHLIEISKLRQQLQHSLKGSRSIVEKEEASQTQPKRISTSSSNTALSRPLICRVPSYSECVNQELENVFICDQWRREEETALEVRDGGRAPVPALHQMSCCSPAADTEKDCRLGSPLPEFSSSPKPNNSFMFKREPPEGCEKVKVFEDLMSPGFPIFSCPDRNKVNFIPSGSAFCPVKLLCSSLFPSDASLQKQTSEHCSIRKCLLLS", "length": 290, "header": "tr|A0A8M9NZW5-1|A0A8M9NZW5_DANRE Isoform 1 of Glucocorticoid-induced transcript 1 protein isoform X1 OS=Danio rerio OX=7955 GN=glcci1b PE=4 SV=1 CANONICAL=A0A8M9NZW5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P8K7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW5/entry#A0A8M9P8K7-1", "sequence": { "sequence": "MKQVTKPTRNHSENHFVTSGRARQMPALDNLPEQYLTGHWPREQNQPQPACMTDKATQTPAIWTEDGGEANTHKRSASWGSADHLIEISKLRQQLQHSLKGSRSIVEKEEASQTQPKRISTSSSNTALSRPLICRVPSYSECVNQELENVFICDQWRREEETALEVRDGGRAPVPALHQMSCCSPAADTEKDCRLGSPLPEFSSSPKPNNSFMFKREPPEGCEKVKVFEDLM", "length": 232, "header": "tr|A0A8M9P8K7-1|A0A8M9P8K7_DANRE Computationally mapped isoform of Glucocorticoid-induced transcript 1 protein isoform X2 OS=Danio rerio OX=7955 GN=glcci1b PE=4 SV=1 CANONICAL=A0A8M9NZW5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100332369", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100332369", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZW5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "podocyte development", "id": "GO:0072015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072015", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZW5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 209, "end_pos": 211 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9NZX0-1", "uniprot_ac": "A0A8M9NZX0", "uniprot_id": "A0A8M9NZX0_DANRE", "mass": { "chemical_mass": 43473.0, "monoisotopic_mass": 43473.0 }, "refseq": { "ac": "XP_021322712", "name": "zinc finger protein 385D isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322712" }, "gene_names": [ { "name": "znf385d", "type": "recommended", "evidence": [ { "id": "A0A8M9NZX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0" } ] }, { "name": "znf385d", "type": "synonym", "evidence": [ { "id": "XP_021322712", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322712" } ] } ], "protein_names": [ { "name": "Zinc finger protein 385D isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9NZX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 385D isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322712", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322712" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322712", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322712" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "znf385d", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130201-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130201-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9NZX0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9NZX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "797951", "url": "https://www.ncbi.nlm.nih.gov/gene/797951", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:797951", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797951", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9NZX0", "url": "https://www.orthodb.org/?gene=A0A8M9NZX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23067", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23067", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23067:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23067:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322712", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322712", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9NZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9NZX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P8L6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P8L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDX8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLK3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130201-2", "url": "https://zfin.org/ZDB-GENE-130201-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTMESMFIGNACQSGLVPALVRAPLPAVPSSLGMKHFVPFALDGGSALSLIPSFSSMNAVQKAVLHHTISTSAPSKRKAMSCGVCHLRFNSQSQALAHYKGTKHAKKLKSLDAPKCLKHKSSSASRENTNKELPKGLVPSTVAYSEDRKGGDAGALVAPSSPSSAPASGPSTDSTESASVSGEEDGSSCTPVPPESEENHSGTSPESETEDEKALRLLYCSLCKVAVNSVSQLDAHNSGTKHKTMLEARSGNGSIKSFPRTGQKSKLPTDASKTADTGLQNKTFHCETCDVRVNSETQLKQHISSRRHKDRAAGKPAKPKFSPYTKTQRGASKQTQVKMPVGKDLCSPLTTRIMPSHLAAVAAAAASIGSTFPLRACHNPTLFQTQSLPAALLRPAPGPIRTAHTPLLFAPY", "length": 412, "header": "tr|A0A8M9NZX0-1|A0A8M9NZX0_DANRE Isoform 1 of Zinc finger protein 385D isoform X1 OS=Danio rerio OX=7955 GN=znf385d PE=4 SV=1 CANONICAL=A0A8M9NZX0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9NZX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0/entry#A0A8M9NZX0-1", "sequence": { "sequence": "MTMESMFIGNACQSGLVPALVRAPLPAVPSSLGMKHFVPFALDGGSALSLIPSFSSMNAVQKAVLHHTISTSAPSKRKAMSCGVCHLRFNSQSQALAHYKGTKHAKKLKSLDAPKCLKHKSSSASRENTNKELPKGLVPSTVAYSEDRKGGDAGALVAPSSPSSAPASGPSTDSTESASVSGEEDGSSCTPVPPESEENHSGTSPESETEDEKALRLLYCSLCKVAVNSVSQLDAHNSGTKHKTMLEARSGNGSIKSFPRTGQKSKLPTDASKTADTGLQNKTFHCETCDVRVNSETQLKQHISSRRHKDRAAGKPAKPKFSPYTKTQRGASKQTQVKMPVGKDLCSPLTTRIMPSHLAAVAAAAASIGSTFPLRACHNPTLFQTQSLPAALLRPAPGPIRTAHTPLLFAPY", "length": 412, "header": "tr|A0A8M9NZX0-1|A0A8M9NZX0_DANRE Isoform 1 of Zinc finger protein 385D isoform X1 OS=Danio rerio OX=7955 GN=znf385d PE=4 SV=1 CANONICAL=A0A8M9NZX0-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P8L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0/entry#A0A8M9P8L6-1", "sequence": { "sequence": "MTMESMFIGNACQSGLVPALVRAPLPAVPSSLGMKHFVPFALDGGSALSLIPSFSSMNAVQKAVLHHTISTSAPSKRKAMSCGVCHLRFNSQSQALAHYKGTKHAKKLKSLDAPKCLKHKSSSASRENTNKELPKGLVPSTVAYSEDRKGGDAGALVAPSSPSSAPASGPSTDSTESASVSGEEDGSSCTPVPPESEENHSGTSPESETEDEKALRLLYCSLCKVAVNSVSQLDAHNSGTKHKTMLEARSGNGSIKSFPRTGQKSKLPTDASKTADTGLQNKTFHCETCDVRVNSETQLKQHISSRRHKDRAAGKPAKPKFSPYTKTQRGASKQTVKMPVGKDLCSPLTTRIMPSHLAAVAAAAASIGSTFPLRACHNPTLFQTQSLPAALLRPAPGPIRTAHTPLLFAPY", "length": 411, "header": "tr|A0A8M9P8L6-1|A0A8M9P8L6_DANRE Computationally mapped isoform of Zinc finger protein 385D isoform X2 OS=Danio rerio OX=7955 GN=znf385d PE=4 SV=1 CANONICAL=A0A8M9NZX0-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PDX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0/entry#A0A8M9PDX8-1", "sequence": { "sequence": "MTMESMFIGNACQSGLVPALVRAPLPAVPSSLGMKHFVPFALDGGSALSLIPSFSSSQALAHYKGTKHAKKLKSLDAPKCLKHKSSSASRENTNKELPKGLVPSTVAYSEDRKGGDAGALVAPSSPSSAPASGPSTDSTESASVSGEEDGSSCTPVPPESEENHSGTSPESETEDEKALRLLYCSLCKVAVNSVSQLDAHNSGTKHKTMLEARSGNGSIKSFPRTGQKSKLPTDASKTADTGLQNKTFHCETCDVRVNSETQLKQHISSRRHKDRAAGKPAKPKFSPYTKTQRGASKQTQVKMPVGKDLCSPLTTRIMPSHLAAVAAAAASIGSTFPLRACHNPTLFQTQSLPAALLRPAPGPIRTAHTPLLFAPY", "length": 376, "header": "tr|A0A8M9PDX8-1|A0A8M9PDX8_DANRE Computationally mapped isoform of Zinc finger protein 385D isoform X3 OS=Danio rerio OX=7955 GN=znf385d PE=4 SV=1 CANONICAL=A0A8M9NZX0-1" }, "locus": {} }, { "isoform_ac": "A0AC58HLK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0/entry#A0AC58HLK3-1", "sequence": { "sequence": "MTMESMFIGNACQSGLVPALVRAPLPAVPSSLGMKHFVPFALDGGSALSLIPSFSSSQALAHYKGTKHAKKLKSLDAPKCLKHKSSSASRENTNKELPKGLVPSTVAYSEDRKGGDAGALVAPSSPSSAPASGPSTDSTESASVSGEEDGSSCTPVPPESEENHSGTSPESETEDEKALRLLYCSLCKVAVNSVSQLDAHNSGTKHKTMLEARSGNGSIKSFPRTGQKSKLPTDASKTADTGLQNKTFHCETCDVRVNSETQLKQHISSRRHKDRAAGKPAKPKFSPYTKTQRGASKQTVKMPVGKDLCSPLTTRIMPSHLAAVAAAAASIGSTFPLRACHNPTLFQTQSLPAALLRPAPGPIRTAHTPLLFAPY", "length": 375, "header": "tr|A0AC58HLK3-1|A0AC58HLK3_DANRE Computationally mapped isoform of Zinc finger protein 385D isoform X4 OS=Danio rerio OX=7955 GN=znf385d PE=4 SV=1 CANONICAL=A0A8M9NZX0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:797951", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797951", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6AXX3-1", "protein_name": "Zinc finger protein 385D", "gene_name": "Znf385d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRKIMYFGGTCQSPALPALIHPPAPPLQPSLDIKPFLPFPLDTAATVNLFPNFNAMDPIQKAVINHTFGFPLPHRKKQIISCNICQLRFNSDSQAAAHYKGTKHAKKLKALESMKNKQKSVTAKDSAKTTFTSITTNPITTSSDKTESTAGTQVIARSADMRKSSEVTTELTSNAEKSLTAAVAAGNNSSPPTETEEEKAKRLLYCSLCKVAVNSASQLEAHNSGTKHKTMLEARNGSGTIKAFPRAGMKGKGPVNKGNTGLQNKTFHCEICDVHVNSETQLKQHISSRRHKDRASGKPPKPKYSPYNKLQKAAHPLGVKLVFSKEPSKPLTPRILPNPLAAAAAAAAVAVNSPFSLRTAPAATLFQTSALPPALLRPAPGPIRTTHTPVLFSPY", "length": 395 }, "evidence": [ { "id": "RGD:1359606", "url": "https://alliancegenome.org/gene/RGD:1359606#orthology", "database": "AGR" }, { "id": "HGNC:26191", "url": "https://alliancegenome.org/gene/HGNC:26191#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130201-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130201-2#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9H6B1-1", "protein_name": "Zinc finger protein 385D", "gene_name": "ZNF385D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRNIMYFGGTCQSPALPALVRPPAPPLQPSLDIKPFLPFPLDTAAAVNLFPNFNAMDPIQKAVINHTFGVPLPHRRKQIISCNICQLRFNSDSQAAAHYKGTKHAKKLKALEAMKNKQKSVTAKDSAKTTFTSITTNTINTSSDKTDGTAGTPAISTTTTVEIRKSSVMTTEITSKVEKSPTTATGNSSCPSTETEEEKAKRLLYCSLCKVAVNSASQLEAHNSGTKHKTMLEARNGSGTIKAFPRAGVKGKGPVNKGNTGLQNKTFHCEICDVHVNSETQLKQHISSRRHKDRAAGKPPKPKYSPYNKLQKTAHPLGVKLVFSKEPSKPLAPRILPNPLAAAAAAAAVAVSSPFSLRTAPAATLFQTSALPPALLRPAPGPIRTAHTPVLFAPY", "length": 395 }, "evidence": [ { "id": "RGD:1359606", "url": "https://alliancegenome.org/gene/RGD:1359606#orthology", "database": "AGR" }, { "id": "HGNC:26191", "url": "https://alliancegenome.org/gene/HGNC:26191#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130201-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130201-2#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9NZX0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9NZX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZX0" }, { "id": "PS00028", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 104, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 281, "end_pos": 283 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P054-1", "uniprot_ac": "A0A8M9P054", "uniprot_id": "A0A8M9P054_DANRE", "mass": { "chemical_mass": 47283.0, "monoisotopic_mass": 47283.0 }, "refseq": { "ac": "XP_021322842", "name": "required for meiotic nuclear division protein 1 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322842" }, "gene_names": [ { "name": "rmnd1", "type": "recommended", "evidence": [ { "id": "A0A8M9P054", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P054" } ] }, { "name": "rmnd1", "type": "synonym", "evidence": [ { "id": "XP_021322842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322842" } ] }, { "name": "zgc:113022", "type": "synonym", "evidence": [ { "id": "XP_021322842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322842" }, { "id": "A0A8M9P054", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P054" } ] } ], "protein_names": [ { "name": "Required for meiotic nuclear division protein 1 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P054", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P054/entry#names_and_taxonomy" } ] }, { "name": "required for meiotic nuclear division protein 1 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322842", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322842" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322842", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322842" } ] } ], "disease": [ { "disease_id": "DOID:0111481", "recommended_name": { "id": "DOID:0111481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111481", "name": "combined oxidative phosphorylation deficiency 11", "description": "A combined oxidative phosphorylation deficiency characterized by neonatal hypotonia, lactic acidosis, death in infancy and in some cases respiratory insufficiency, foot deformities, or seizures that has_material_basis_in homozygous or compound heterozygous mutation in the RMND1 gene on chromosome 6q25.1." }, "synonyms": [ { "id": "DOID:0111481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111481", "name": "infantile encephaloneuromyopathy due to mitochondrial translation defect", "description": "" }, { "id": "DOID:0111481", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111481", "name": "COXPD11", "description": "" }, { "id": "MONDO:0013969", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013969", "name": "combined oxidative phosphorylation defect type 11", "description": "Any combined oxidative phosphorylation deficiency in which the cause of the disease is a mutation in the RMND1 gene." }, { "id": "MONDO:0013969", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013969", "name": "COXPD11", "description": "" }, { "id": "MONDO:0013969", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013969", "name": "RMND1 combined oxidative phosphorylation deficiency", "description": "" }, { "id": "MONDO:0013969", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013969", "name": "combined oxidative phosphorylation defect type 11", "description": "" }, { "id": "MONDO:0013969", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013969", "name": "combined oxidative phosphorylation deficiency caused by mutation in RMND1", "description": "" }, { "id": "MONDO:0013969", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013969", "name": "combined oxidative phosphorylation deficiency type 11", "description": "" }, { "id": "MONDO:0013969", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013969", "name": "combined oxidative phosphorylation deficiency 11", "description": "" }, { "id": "MIM:614922", "resource": "MIM", "url": "https://www.omim.org/entry/614922", "name": "Combined oxidative phosphorylation deficiency 11", "description": "Combined oxidative phosphorylation deficiency 11" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111481", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111481" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P054", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P054" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rmnd1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P054", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050522-21", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-21", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "553810", "url": "https://www.ncbi.nlm.nih.gov/gene/553810", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051624", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051624", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:553810", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553810", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KLGMWEA", "url": "https://omabrowser.org/oma/group/KLGMWEA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P054", "url": "https://www.orthodb.org/?gene=A0A8M9P054", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16255", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16255", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16255:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16255:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02582", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02582", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322842", 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"database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFVKMLWRLQQPLKSTQACGFTLRQINGLNSVTSNRLNCSTLALQTPFKDQRNCPAILHHCILQKGGPRFQVLTPLNFISKTWSFQVRLQSTTAATNIVLKQGGMSGKRTFKGPRTKQPSRASQPSLEEDLMQCIAYATADQYHLPTLCHDLIAHGFSEIKEFPRDASNVLVMGTDNSAKPYDSGTIFFFREGSVVFWNVEDKTMKTTMKILEQHEIQPYEVALVYWENEEINYTVGEGHSKLRHGVFLFNEELDYEQVILEKFAFSNALSLSVKLAIWEVTLDSFVESIQSIPEMLKSGQRVKLSRADVMQKIGELFSLRHCINLSSDLLITPDFYWDREDLELLYDKTCQFLNINRRVKVVNEKLQHCTELTDLMRNHLSEKHSLRLEWMIVVLITIEVMFELARVIF", "length": 410, "header": "tr|A0A8M9P054-1|A0A8M9P054_DANRE Isoform 1 of Required for meiotic nuclear division protein 1 homolog isoform X1 OS=Danio rerio OX=7955 GN=rmnd1 PE=3 SV=1 CANONICAL=A0A8M9P054-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P054-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P054/entry#A0A8M9P054-1", "sequence": { "sequence": "MFVKMLWRLQQPLKSTQACGFTLRQINGLNSVTSNRLNCSTLALQTPFKDQRNCPAILHHCILQKGGPRFQVLTPLNFISKTWSFQVRLQSTTAATNIVLKQGGMSGKRTFKGPRTKQPSRASQPSLEEDLMQCIAYATADQYHLPTLCHDLIAHGFSEIKEFPRDASNVLVMGTDNSAKPYDSGTIFFFREGSVVFWNVEDKTMKTTMKILEQHEIQPYEVALVYWENEEINYTVGEGHSKLRHGVFLFNEELDYEQVILEKFAFSNALSLSVKLAIWEVTLDSFVESIQSIPEMLKSGQRVKLSRADVMQKIGELFSLRHCINLSSDLLITPDFYWDREDLELLYDKTCQFLNINRRVKVVNEKLQHCTELTDLMRNHLSEKHSLRLEWMIVVLITIEVMFELARVIF", "length": 410, "header": "tr|A0A8M9P054-1|A0A8M9P054_DANRE Isoform 1 of Required for meiotic nuclear division protein 1 homolog isoform X1 OS=Danio rerio OX=7955 GN=rmnd1 PE=3 SV=1 CANONICAL=A0A8M9P054-1" }, "locus": {} }, { "isoform_ac": "A0AC58HN36-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P054/entry#A0AC58HN36-1", "sequence": { "sequence": "MYRLNCSTLALQTPFKDQRNCPAILHHCILQKGGPRFQVLTPLNFISKTWSFQVRLQSTTAATNIVLKQGGMSGKRTFKGPRTKQPSRASQPSLEEDLMQCIAYATADQYHLPTLCHDLIAHGFSEIKEFPRDASNVLVMGTDNSAKPYDSGTIFFFREGSVVFWNVEDKTMKTTMKILEQHEIQPYEVALVYWENEEINYTVGEGHSKLRHGVFLFNEELDYEQVILEKFAFSNALSLSVKLAIWEVTLDSFVESIQSIPEMLKSGQRVKLSRADVMQKIGELFSLRHCINLSSDLLITPDFYWDREDLELLYDKTCQFLNINRRVKVVNEKLQHCTELTDLMRNHLSEKHSLRLEWMIVVLITIEVMFELARVIF", "length": 377, "header": "tr|A0AC58HN36-1|A0AC58HN36_DANRE Computationally mapped isoform of Required for meiotic nuclear division protein 1 homolog isoform X2 OS=Danio rerio OX=7955 GN=rmnd1 PE=3 SV=1 CANONICAL=A0A8M9P054-1" }, "locus": {} }, { "isoform_ac": "A0AC58HN37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P054/entry#A0AC58HN37-1", "sequence": { "sequence": "MKTTMKILEQHEIQPYEVALVYWENEEINYTVGEGHSKLRHGVFLFNEELDYEQVILEKFAFSNALSLSVKLAIWEVTLDSFVESIQSIPEMLKSGQRVKLSRADVMQKIGELFSLRHCINLSSDLLITPDFYWDREDLELLYDKTCQFLNINRRVKVVNEKLQHCTELTDLMRNHLSEKHSLRLEWMIVVLITIEVMFELARVIF", "length": 206, "header": "tr|A0AC58HN37-1|A0AC58HN37_DANRE Computationally mapped isoform of Required for meiotic nuclear division protein 1 homolog isoform X3 OS=Danio rerio OX=7955 GN=rmnd1 PE=3 SV=1 CANONICAL=A0A8M9P054-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:553810", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553810", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AVV0-1", "protein_name": "Required for meiotic nuclear division 1 homolog", "gene_name": "RMND1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPAGLLRALAGSHCILSKTCQCQRLVHRTLKPLKELETTCSSLTESQSLDMFFPDTAAGGLNKSRILEMNQKIASTSVLSPLNAAHFPTGSLFGTHQKVTHRPNLLGSKRFVKILGRHSSSVSTETFPKQDFPKIKRPLKASRTRQPSRTNLPVLSVNEDLMHCTAFATADEYHLGNLSQDLAAHGYVEVTSLPRDAANILVMGVENSAKEGDPGTIFFFREGAAVFWNVKDKTMKHVMQVLEKHEIQPYEVALVHWENEELNYIKTEGQSKLHRGEIRLNSELDIDDAILEKFAFSNALCLSVKLAIWEASLDKFIESIQSIPEALKAGKKVKLSHEEVMQKMGELFALRHRINLSSDFLITPDFYWDRENLEELYDKTCRFLSITRRVKVMNEKLQHCMELTDLMRNHLTEKRTLRLEWMIVILITIEVGNFRENNLAEKSMTLS", "length": 447 }, "evidence": [ { "id": "A0A8M9P054", "url": "https://omabrowser.org/oma/group/A0A8M9P054/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8C2MPE4-1", "protein_name": "Required for meiotic nuclear division protein 1 homolog isoform X1", "gene_name": "Rmnd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPARLLQTLASLSSASLKAYQCKRLARLPLKPLTESESTACRKSLKIQQCLDSFFPQITADSLNNPKILEMSRIISNESRPFSLNAVHCWDGKACLPTMHPFGTPRKVAHKPNLLCAKWFIKTVKRHHSVSTETLVPKQDLPQIKRPLKASRTRQPSRTNLPELSVNEDLMQCTAFATADEYHLGSLSQELVSCGYVEVTSLPRDAANVLVMGVENTAKEGDPGMIFLFREGATVFWNVRDKTVKHVMQVLERHETQPYEVALVYWENEELNYMKIEGQSKLHRGEIKLNSELDLDDAILEKFAFSNALCLSVKLAIWEATLDKFIESIQSIPEALKAGKKVKLSHKEVMQKMGELFALRHRINLSSDFLLTPDFYWDRANLEELYDKTCQFLSIARRVKVMNEKLQHCMELTDLMRNHLNENRALRLEWMIVILITIEVMFELGRVFF", "length": 449 }, "evidence": [ { "id": "A0A8M9P054", "url": "https://omabrowser.org/oma/group/A0A8M9P054/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0XIY0-1", "protein_name": "Required for meiotic nuclear division 1 homolog", "gene_name": "RMND1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLKLLRLQTTSFHSLTTIGRCQRFNKTGHRLLKLDNDVDRTDHRTAKKIGNLPAPKTASPCLTSPYVQVKNWQMMQGNVSALGKSVYYQGGEVFFPPWKRFGLAAMENYKLSVEYIKNLGNISSRFYSIVSTSKIIPKSSTQPVKRPPKAPRTKQPSRANQPLLSDMENLMQCTAFATADEYHLGNLCHDLTSHGYVEITSLPRDAANVLVMGTEKSAKEDDPGMVFFFREGAVVFWNVDEKSMKNIMRVLEQHEIQPYEVALVHWENEEINYRIGEGQSKLHKGEILLNSELDTDEVVLQKFAFSNALCLSVKLAIWESLLDNFVESIQSIPEILKSRRKVKLSHADVMQKIGELFALRHRINLSSDLLITPDFYWDREKLEELYDKTCQFLNINRRVKVMNEKLQHCMELTDLMRNHLNEKHALRLEWMIVILITIEVMFELARVVL", "length": 450 }, "evidence": [ { "id": "A0A8M9P054", "url": "https://omabrowser.org/oma/group/A0A8M9P054/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9PU34-1", "protein_name": "Required for meiotic nuclear division 1 homolog", "gene_name": "Rmnd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPARQLQTLAGLHSISSKAHQCQRLTRLTLRPLTKFESTACHNSLTIQQHLDSFLPSITADSLNKPKIPETSRVISNASRLFPLNAVHWLDRKEHRPSMHAFGTHRSMTHKPNFLCSKWFIKAVKRHHSSVSNEALVPKQDLPQIKRPLKASRTRQPSRTNLPDLSVNEDLMQCTAFATADEYHLGSLSQELVSCGYVEVTSLPRDAANILVMGVESSAKEGDAGTIFLFREGAAVFWNVKDKTMKHVMQVLERHETQPYEVALVHWENEELNYTKTEGQSKLHRGEIKLNSELDLDDSILEKFAFSNALCLSVKLAIWEATLDKFIESIQSIPEALKAGKKVKLSHKEVMQKMGELFALRHRINLSSDFLITPDFYWDRANLEELYDKTCQFLSITRRVKVMNEKLQHCMELTDLMRNHLNEKRALRLEWMIVILITIEVMFELGRVFF", "length": 450 }, "evidence": [ { "id": "FB:FBgn0030678", "url": "https://alliancegenome.org/gene/FB:FBgn0030678#orthology", "database": "AGR" }, { "id": "RGD:1309546", "url": "https://alliancegenome.org/gene/RGD:1309546#orthology", "database": "AGR" }, { "id": "MGI:1913334", "url": "https://alliancegenome.org/gene/MGI:1913334#orthology", "database": "AGR" }, { "id": "HGNC:21176", "url": "https://alliancegenome.org/gene/HGNC:21176#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-21", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-21#orthology", "database": "AGR" }, { "id": "SGD:S000002690", "url": "https://alliancegenome.org/gene/SGD:S000002690#orthology", "database": "AGR" }, { "id": "A0A8M9P054", "url": "https://omabrowser.org/oma/group/A0A8M9P054/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MS81-1", "protein_name": "Required for meiotic nuclear division 1 homolog", "gene_name": "RMND1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVMSARLLRALAGSRHILSKACQCQRLIHQMLKPLKEFETAARTALTRNQNLDLFFPDAATGGLNKSQILWMNQKISNTNVLPPFNTACCQDGKAHLPTRNSVSTHRKVTHKPNLLGSKWFIKILKRHSSSVSTETVSKQDFPQIKRPLKASRTRQPSRTNLPVLPVNEDLMQCTAFATADEYHLGSLSQDLTSHGYVEVTSLPRDAANILVMGVENSAKEGDPGTIFFFREGAAVFWNVKDQTMKHVMQVLEKHEIQPYEIALVHWENEELNYTKTEGQSKLHRGEIRLNSELDLDDVILEKFAFSNALCLSVKLAIWEASLDKFVESIQSIPEALKAGKKVKLSHEEVMQKMGELFALRHRINLSSDFLITPDFYWDRENLEELYDKTCRFLSITRRVKVMNEKLQHCMELTDLMRNHLTEKRALRLEWMIVILITIEVLFELGRVFFLIK", "length": 453 }, "evidence": [ { "id": "A0A8M9P054", "url": "https://omabrowser.org/oma/group/A0A8M9P054/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P43620-1", "protein_name": "Sporulation protein RMD8", "gene_name": "RMD8", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSYKANQPSPGEMPKRSPSILVTDARTSKNRMSAPFAGHAAGSRKNMENAGVTKSQGVRSSAIGPSPLQSFTHPRRRSSGRFSDISIDNILSDNSDIPSARREERLSSSSSDRPRQYERLSSRRKMINPLPPRTSKTSQKLVLIPEDDNLNHFQTLPTNALDRQRPKVGSMKSNSFDRLPRYSKEKSMARITAYNVADGFNLNQLYKFLQETHEVSPRLYDECLYVAYTLPLLPGKGGFRIKSNLSKKTMGGKTLIDNLIDTSEQRDHHYEYYSGVETVEDANNNYELETSGNNNNANQDTTTVPDHLPNPVGQQDSFNPMEPQFFAEETPLEIEKRERTERINMLKKEENDSDASCGNDNNNKNNDKSKLYAVEGNDQYVQSSRSPASPSSISTPSPPSSSQNDFDRVYKMHRDNDHEGNDRHAEIFIFHYGVIVFWNFTEIQEKNILGDITFADYKNLMIRPLDEQDIETEQFHFEYDRDTERPRIFNDIVTLRSGDHIIELTLSHAIAQSSKLSRFESRISPILISVTKLPKRLALYGTLGLKREQLLKKSGKLFKLRVDVNLSSTILDTPEFFWSFEPSLHPLYVAMREYLEIDQRVQVLNDRCKVFLEFFDICVDSVAERNMARVTWWFILVILFGVIFSLTEIFVRYVIIHRHTST", "length": 662 }, "evidence": [ { "id": "FB:FBgn0030678", "url": "https://alliancegenome.org/gene/FB:FBgn0030678#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q03441-1", "protein_name": "Sporulation protein RMD1", "gene_name": "RMD1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVDSNDDQPERHALLHNDIQTSNNSRPSLVQKKYLPTPQDTRKSRASYTGSAMINPTSKQSRTGSGAQRTSRTAQKLKLLPEEPFQRDSERLTDLKNQEVYSQVNRIKDKPARRDAEKLGKAHRHLLPRSTAYCTASSYNMKELVRWLKDCRKLHHTHPKLFDECLYTPFIYNDWRGDKRFEDEDVIRLDDEGGEIIVSDKHPDLFIFEYGVVVMWGFTEREEKAFLNDIEKFEKEKLAEEDIQVEEFNYYVTKSYQPRIYNDFITLRDGSNYMVKLSISHAIAQSVKISLFEELVDNTIEDTQDIPQEIAYSGKVSMSKEDIMKSIGELFILRININLHGSVLDSPEIMWSEPQLEPIYQATRGYLEINQRVSLLNQRLEVISDLLQMLKEQLGHSHEEYLEFIVILLVGVEVLISVINIVVDMLASQH", "length": 430 }, "evidence": [ { "id": "FB:FBgn0030678", "url": "https://alliancegenome.org/gene/FB:FBgn0030678#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q05648-1", "protein_name": "MIOREX complex component 10", "gene_name": "MRX10", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLSFRSLTSTFGFVSRFQIRRLGTSLSIQNLEVQDGRWKGKLATEKKTNREHKSVDTNIKTMKMLKNPKNSTRYLRRSFVPNHRKQENGRDILEDSLSKDHLKVKSCITITTGEGYDLKRCMKLLTMQGLQPTNLIPDEIVSFSYQDNGNKGDVMILGQNGSIVSWGFSESSVRNCIVPIVKAASLNPLNGEDFETEDMDYVEIEGEQDFDKLSSLDNKVTPRIACESFLSGDLIIINSLDSDQGMLDKAAFSSGLSRSTNLAVLEEAMEKHISKTRTITENISKGTKLNLRSSDALKSIGRLFLIRGKLNLYSELIETPDLYWSEPQLEEIFKNVSRYLDIGPRINILNSKLDYSTDECRALISLLNERNSTFLEWIIIYLIAFELCFEIYHFYQKYSSYCSEPTNDDLDATK", "length": 414 }, "evidence": [ { "id": "FB:FBgn0030678", "url": "https://alliancegenome.org/gene/FB:FBgn0030678#orthology", "database": "AGR" }, { "id": "RGD:1309546", "url": "https://alliancegenome.org/gene/RGD:1309546#orthology", "database": "AGR" }, { "id": "MGI:1913334", "url": "https://alliancegenome.org/gene/MGI:1913334#orthology", "database": "AGR" }, { "id": "HGNC:21176", "url": "https://alliancegenome.org/gene/HGNC:21176#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-21", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-21#orthology", "database": "AGR" }, { "id": "SGD:S000002690", "url": "https://alliancegenome.org/gene/SGD:S000002690#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8CI78-1", "protein_name": "Required for meiotic nuclear division protein 1 homolog", "gene_name": "Rmnd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSRLLHTLASLHSISAKAHQCQRLTWLTLRPLRKSESTTCHNGLTIQQHLHSFFPSITADSLNKPEILEMSRITSDTSRLFPLNAVHWLDGKEHWPSMHPFGTHRSMTHKPNLLCSKWFIKAVKRHHSSVSNEALVPKQDLPQIKRPLKASRTRQPSRTNLPDLSVNEDLMQCTAFATADEYHLGSLSQELVSCGYVEVTSLPRDAANILVMGVESSAKEGDPGTIFLFREGAAVFWNVKEKTMKHVMQVLERHETQPYEVALVHWENEELNYIKTEGQSKLHRGEIKLNSELDLDDAILEKFAFSNALCLSVKLAIWEATLDKFIESIQSIPEALKAGKKVKLSHKEVMQKMGELFALRHRINLSSDFLITPDFYWDRANLEELYDKTCQFLSITRRVKVMNEKLQHCMELTDLMRNHLNEKRALRLEWMIVILITIEVMFELGRVFF", "length": 450 }, "evidence": [ { "id": "FB:FBgn0030678", "url": "https://alliancegenome.org/gene/FB:FBgn0030678#orthology", "database": "AGR" }, { "id": "RGD:1309546", "url": "https://alliancegenome.org/gene/RGD:1309546#orthology", "database": "AGR" }, { "id": "MGI:1913334", "url": "https://alliancegenome.org/gene/MGI:1913334#orthology", "database": "AGR" }, { "id": "HGNC:21176", "url": "https://alliancegenome.org/gene/HGNC:21176#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-21", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-21#orthology", "database": "AGR" }, { "id": "SGD:S000002690", "url": "https://alliancegenome.org/gene/SGD:S000002690#orthology", "database": "AGR" }, { "id": "A0A8M9P054", "url": "https://omabrowser.org/oma/group/A0A8M9P054/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NWS8-1", "protein_name": "Required for meiotic nuclear division protein 1 homolog", "gene_name": "RMND1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPATLLRAVARSHHILSKAHQCRRIGHLMLKPLKEFENTTCSTLTIRQSLDLFLPDKTASGLNKSQILEMNQKKSDTSMLSPLNAARCQDEKAHLPTMKSFGTHRRVTHKPNLLGSKWFIKILKRHFSSVSTETFVPKQDFPQVKRPLKASRTRQPSRTNLPVLSVNEDLMHCTAFATADEYHLGNLSQDLASHGYVEVTSLPRDAANILVMGVENSAKEGDPGTIFFFREGAAVFWNVKDKTMKHVMKVLEKHEIQPYEIALVHWENEELNYIKIEGQSKLHRGEIKLNSELDLDDAILEKFAFSNALCLSVKLAIWEASLDKFIESIQSIPEALKAGKKVKLSHEEVMQKIGELFALRHRINLSSDFLITPDFYWDRENLEGLYDKTCQFLSIGRRVKVMNEKLQHCMELTDLMRNHLNEKRALRLEWMIVILITIEVMFELGRVFF", "length": 449 }, "evidence": [ { "id": "FB:FBgn0030678", "url": "https://alliancegenome.org/gene/FB:FBgn0030678#orthology", "database": "AGR" }, { "id": "RGD:1309546", "url": "https://alliancegenome.org/gene/RGD:1309546#orthology", "database": "AGR" }, { "id": "MGI:1913334", "url": "https://alliancegenome.org/gene/MGI:1913334#orthology", "database": "AGR" }, { "id": "HGNC:21176", "url": "https://alliancegenome.org/gene/HGNC:21176#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-21", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-21#orthology", "database": "AGR" }, { "id": "SGD:S000002690", "url": "https://alliancegenome.org/gene/SGD:S000002690#orthology", "database": "AGR" }, { "id": "A0A8M9P054", "url": "https://omabrowser.org/oma/group/A0A8M9P054/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VXQ8-1", "protein_name": "DUF155 domain-containing protein", "gene_name": "Dmel\\CG11679", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNFARLRFGQMVLGGLRIPRQQTQTQWMMDRRRWLASEATSSAAAPAQAASVPRTQTQPRVKPLPLAEERLESILSPIRTRIIRKKRLAIDELSALGFLNTRGYTTAEEYNLEDLQIALREQNLYETKRFFSTDNLDVEQNVLFVAAKYPTGQQPREIFFFREGSVVFWNCSDIETNNVLSFLRAFERESYVSALVHGESEVMPYTYIPSTAVDVEGDLVAESSDFNVTSRAFFQNGKFFVTADTDSFLYKYTFSNAMAQSIKLGMWEATLDRYIDSIEHLTEDLKRGRRLRISRAAMLRKTGELFALRHVINLSSDLLDAPDFYWDREELEALYLQVCSYFSISRRTKVMNEKINHCVELAELVSHNLNDAHHIRLEWMIIILIMVEVGFEVLHFVSDHSDSHKLEVLPLAAPAASIPN", "length": 420 }, "evidence": [ { "id": "FB:FBgn0030678", "url": "https://alliancegenome.org/gene/FB:FBgn0030678#orthology", "database": "AGR" }, { "id": "RGD:1309546", "url": "https://alliancegenome.org/gene/RGD:1309546#orthology", "database": "AGR" }, { "id": "MGI:1913334", "url": "https://alliancegenome.org/gene/MGI:1913334#orthology", "database": "AGR" }, { "id": "HGNC:21176", "url": "https://alliancegenome.org/gene/HGNC:21176#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-21", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-21#orthology", "database": "AGR" }, { "id": "SGD:S000002690", "url": "https://alliancegenome.org/gene/SGD:S000002690#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P054", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P054" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of mitochondrial translation", "id": "GO:0070131", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070131", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P054", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P054" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P054", "database": "UniProtKB", "url": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HR20-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HR20-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HR30", "url": "https://www.uniprot.org/uniprotkb/A0AC58HR30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HR30-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HR30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HR41", "url": "https://www.uniprot.org/uniprotkb/A0AC58HR41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HR41-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HR41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131127-188", "url": "https://zfin.org/ZDB-GENE-131127-188", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEVKKVKAAPEKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2692, "header": "tr|A0A8M9P0E4-1|A0A8M9P0E4_DANRE Isoform 1 of Uncharacterized protein si:ch211-266g18.10 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P0E4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0A8M9P0E4-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEVKKVKAAPEKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2692, "header": "tr|A0A8M9P0E4-1|A0A8M9P0E4_DANRE Isoform 1 of Uncharacterized protein si:ch211-266g18.10 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P9B6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0A8M9P9B6-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2678, "header": "tr|A0A8M9P9B6-1|A0A8M9P9B6_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X3 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PEP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0A8M9PEP3-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2662, "header": "tr|A0A8M9PEP3-1|A0A8M9PEP3_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X7 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PP88-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0A8M9PP88-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEVKKVKAAPEKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2691, "header": "tr|A0A8M9PP88-1|A0A8M9PP88_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X2 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PPB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0A8M9PPB3-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEVKKVKAAPEKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2662, "header": "tr|A0A8M9PPB3-1|A0A8M9PPB3_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X10 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQV7-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2662, "header": "tr|A0AC58HQV7-1|A0AC58HQV7_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X6 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQW0-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2677, "header": "tr|A0AC58HQW0-1|A0AC58HQW0_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X4 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQW3-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2648, "header": "tr|A0AC58HQW3-1|A0AC58HQW3_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X15 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQW4-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEVKKVKAAPEKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2661, "header": "tr|A0AC58HQW4-1|A0AC58HQW4_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X14 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQW5-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2647, "header": "tr|A0AC58HQW5-1|A0AC58HQW5_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X17 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQW6-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2663, "header": "tr|A0AC58HQW6-1|A0AC58HQW6_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X5 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQW7-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2662, "header": "tr|A0AC58HQW7-1|A0AC58HQW7_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X9 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQW8-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2661, "header": "tr|A0AC58HQW8-1|A0AC58HQW8_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X13 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQW9-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2662, "header": "tr|A0AC58HQW9-1|A0AC58HQW9_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X8 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQX1-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2647, "header": "tr|A0AC58HQX1-1|A0AC58HQX1_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X16 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQX2-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2646, "header": "tr|A0AC58HQX2-1|A0AC58HQX2_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X21 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQX3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQX3-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2646, "header": "tr|A0AC58HQX3-1|A0AC58HQX3_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X23 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQX6-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2647, "header": "tr|A0AC58HQX6-1|A0AC58HQX6_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X19 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQX7-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2646, "header": "tr|A0AC58HQX7-1|A0AC58HQX7_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X20 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQX9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQX9-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2645, "header": "tr|A0AC58HQX9-1|A0AC58HQX9_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X30 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQY1-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2645, "header": "tr|A0AC58HQY1-1|A0AC58HQY1_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X28 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQY2-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2646, "header": "tr|A0AC58HQY2-1|A0AC58HQY2_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X22 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQY3-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2646, "header": "tr|A0AC58HQY3-1|A0AC58HQY3_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X24 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQY5-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2645, "header": "tr|A0AC58HQY5-1|A0AC58HQY5_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X27 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQY7-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2630, "header": "tr|A0AC58HQY7-1|A0AC58HQY7_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X42 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQY8-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2645, "header": "tr|A0AC58HQY8-1|A0AC58HQY8_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X29 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQY9-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2630, "header": "tr|A0AC58HQY9-1|A0AC58HQY9_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X37 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQZ0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQZ0-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2631, "header": "tr|A0AC58HQZ0-1|A0AC58HQZ0_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X35 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQZ1-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2661, "header": "tr|A0AC58HQZ1-1|A0AC58HQZ1_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X12 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQZ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQZ2-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2632, "header": "tr|A0AC58HQZ2-1|A0AC58HQZ2_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X33 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQZ4-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2631, "header": "tr|A0AC58HQZ4-1|A0AC58HQZ4_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X34 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQZ5-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2629, "header": "tr|A0AC58HQZ5-1|A0AC58HQZ5_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X44 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQZ6-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2633, "header": "tr|A0AC58HQZ6-1|A0AC58HQZ6_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X32 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQZ7-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2631, "header": "tr|A0AC58HQZ7-1|A0AC58HQZ7_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X36 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HQZ9-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2630, "header": "tr|A0AC58HQZ9-1|A0AC58HQZ9_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X41 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR00-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2630, "header": "tr|A0AC58HR00-1|A0AC58HR00_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X38 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR01-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2630, "header": "tr|A0AC58HR01-1|A0AC58HR01_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X40 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR02-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2629, "header": "tr|A0AC58HR02-1|A0AC58HR02_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X43 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR04-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2661, "header": "tr|A0AC58HR04-1|A0AC58HR04_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X11 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR06-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2647, "header": "tr|A0AC58HR06-1|A0AC58HR06_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X18 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR07-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2615, "header": "tr|A0AC58HR07-1|A0AC58HR07_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X46 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR08-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2614, "header": "tr|A0AC58HR08-1|A0AC58HR08_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X49 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR09-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2646, "header": "tr|A0AC58HR09-1|A0AC58HR09_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X26 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR10-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2614, "header": "tr|A0AC58HR10-1|A0AC58HR10_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X47 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR11-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2614, "header": "tr|A0AC58HR11-1|A0AC58HR11_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X48 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR13-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2613, "header": "tr|A0AC58HR13-1|A0AC58HR13_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X50 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR19-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKVAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2646, "header": "tr|A0AC58HR19-1|A0AC58HR19_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X25 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR20-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKAPEITKEKPKPAAKKVAEVIKDRTKPVPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2644, "header": "tr|A0AC58HR20-1|A0AC58HR20_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X31 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR30-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKEAVVIKEKAVPAILKEVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2630, "header": "tr|A0AC58HR30-1|A0AC58HR30_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X39 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HR41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4/entry#A0AC58HR41-1", "sequence": { "sequence": "MAQATKVVKSIPPTAVDAPARAVHPESFTARSHGILLTMSRPAQWVVIITLLISWSIAGVVMFDFVSDDQIASIQDLGSDPALAVNMAIEGIENRINHMNNMFNDANEYIGELLYNPKEALYSAADSSVSYVTEMLTPDELIIETVKYGGTALDEVTEWVRFPVCCLFHLYEDVLDIVFTPVDLLSEAVVQILSGIKTIVQYLSNILEGARDITDIAKLGGTVLDKVTDCIRLPVGYLFYLFEAILEVTIIYPADLTSEVFLQILNVIKNTLSAIFGFFKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADLASEAFLQILNVIKNTLSAIFGFLKGDADITETAKLGGTVLDTVTDWIRLPVGYLFYLFEAILEVTIIYPADMASEAFLQILNVIKNTSSAIFGFLEAWFPKMSTRPTELVEKVAEEATDVKTTVSNYLSSLFVRDEGGIPDVTFDPMKVVSDTVEEFADRRDMLLAYLSNMLMEDKVSDETPQVIRRKGEFLPPMEKVAEVLGKTQDPIYAAYIAVRSTAETDGDELEIKGAEVDSAEDILEEQKVEKTVDGSENDAVASVEEEKAVVDIVDEESSHTPEVTDEEMAKEKDEDTSDSTEMTSDVQDIDDTIDSETEEIPEMVESVSEVGEEEPFVIEKVEDTSDSKEITSNAADVQDVDDNSDVDTEEIPELVGGVSDVGEEEPSEVIDEEIATEKLEDASDSTGLIPSAENVKDTDDILEVDAEVNEVETVEDISEVTNEETSDVPEVIDEEKVEKSDDIFHFAEDKPTELISDAPDVTEDIEISISAVSEDNETIQEADMTDVKDEEMEAEKVDEISYFVEDKSTEITSDATDVKEDTDGFTVTEEKGTIESLQEAAMKMSGNADDEIPNVTEMVEEPDTSDVMDELDEPEKDEDVISVTNERVTTAQDVIFSKEKMGAAELDDHDKLRAKDDSEVDHMEKEIADAENDLQNEIDKDEFKVEDASHQTILGSTAAEEDQDDDDDDEEPVLLTVKHELTDGDDENNNNNDRKRDARTKGLINRKTPKSHSTETDEQKAHKDLHKESAKVLEQVKEAKEKKAREEIYKIIQEMREEKAEGVEEEIVLQQINITVEKVKKEETVKKEEKAKRKEKAHKPKDAKIAKDKPKAVPVKQEDEVAKKETKPAPSKKEAKIVKEKPKAHPAKKEKAKDIKEKAKSGQKEKVAEAVKEKSKPVKKEAEKIDAKVKPAAEKKVDEAPKEKPKVKKEAEVIKKIKLEPERKEAKTPKAKIEPAGLKKDAEAAKEKAKPAPVKKGPEVSREKAKPEPAKKELEAVKEKAKPAPAKKDEVKEKEKPAPVKKAEEIKKAKAAPSRKEAVKEKPKPVSEKKEPAVAVEKAKPKSTKKEAEVEEKVKPAPEKKEAEVIMVKTKPVLKKKEAEVIKEVKPALEKKEAEVIKEKVKPAPVKKEPEVVKEKEPEPKPKREPEIIKEKSAPPKKVEVPKQKAPEKKAPEITKEKPKPAPKKEAEAVKEKAKPEKKEAEAVKEKTKPAPEKETEIIKDKIKAAPVKKEVEVKKEAKPAPVKKETEVIKEKEKPAPEKKEAEAVKEKTKPTSEKKEAEIIKEKVKAAPVKKEVEVKEEAKPAPVKKETEVIKEKEKTAPEKKEAEAVKEKTKPTPEKKEAEVIKEIVKQAPVKKEAEPVKEITKPAPEKKEAEIIKEKVKAAPLKKEVKEKAKPAPVKKEAEVIKQKAKPAPEKKEAKVIKEKVKPAPVKIEAKPVKEITKPAPEKKEAEIIKEKVKSAPVKKEVEVKEEAKPAPEKKEAEVIKEKVKPAPVRKEAEEIKEKAEAVYEKKEAEVAKEIVKPTPLKKEPEVVKEKAPESKPQKEAEIIKEKVKPAPVKKEPEVAKVPKPKKEAELAKEKVKPAPVKKEEKPKAAPKKEAEAIKEKRTPAPEKKVVEVIKEKVKPAPEKKAVLKEKVRPAPEKKEPEVAKEKAPEPKPQKEVEVIKEKAKPALKKKEPKVKEKVQPAPIKKEPELPKEKVPEPTPEPERVEAPKEKAKVIPREKAEITKEKPKPAPKKEAEVKEKATPAPVHKEVEVFKEKVKQAPVKKEPEVPKEKAPEPKPKKTEVIKAKVKPAPEKKEAEVKEKIKPVPEKKEAEVIKERIKPAPVKKEPEVPKEKAPEPKPKKEPEVIKEKVKPAPEKKEAEVIKEKPKAVPEKKEAKVIEKKVIPAPVKKEPEVVKEKAPELTTKKAPEITKEKPKPVPKKEAEVIKEKAKLAPEKKEVEVIKEKVKPAPLKKEPEVHKEKAPEPKSEPTKKVEVPKEKAKPVAKEKEPEITKEKPKPAPKKVAEIKEKVKPASIMKEPEVVKQKTPEPKPKKEPEVVKEKAPEPKPKKEPEVAKEKAKPAPQKKEVIKEKVKLAPVKKVPEVVEEKALKPEPKKDEVGLIGLDLELLNSINQKLSLLDLLRKDIGEMKSDLESTQNQITLLRMDNRTIKEPETIGVKVKPAVKEKAKRDHALINATRTAHIKTERESLKNITKPVPAKKAKEAPKVKIALEPKKKGIIPEKVKEVKETLQKEPELVKDKVEPIEKEIVVEKEVKGEEPEITKDIPEVEEEDIPYFQCFFVDEDDTQYPFFPFSPPLW", "length": 2629, "header": "tr|A0AC58HR41-1|A0AC58HR41_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-266g18.10 isoform X45 OS=Danio rerio OX=7955 GN=si:ch211-266g18.10 PE=4 SV=1 CANONICAL=A0A8M9P0E4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2030, "start_aa": "Thr", "end_pos": 2030, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2030", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:553343", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553343", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "signaling receptor binding", "id": "GO:0005102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005102", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0E4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4" } ], "pmid": "" }, { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0E4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0E4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4" } ], "pmid": "" }, { "name": "junctional sarcoplasmic reticulum membrane", "id": "GO:0014701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014701", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0E4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum membrane", "id": "GO:0033017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0033017", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0E4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "heart contraction", "id": "GO:0060047", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060047", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0E4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4" } ], "pmid": "" }, { "name": "regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum", "id": "GO:0010880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010880", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0E4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4" } ], "pmid": "" }, { "name": "regulation of cardiac muscle cell membrane potential", "id": "GO:0086036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0086036", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0E4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4" } ], "pmid": "" }, { "name": "release of sequestered calcium ion into cytosol by sarcoplasmic reticulum", "id": "GO:0014808", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014808", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0E4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0E4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1119, "end_pos": 1121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2539, "end_pos": 2541, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2568, "end_pos": 2570, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2584, "end_pos": 2586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 822, "end_pos": 824, "annotation": "n_glycosylation_sequon" }, { "start_pos": 900, "end_pos": 902, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 2030 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1119, "end_pos": 1121 }, { "start_pos": 2539, "end_pos": 2541 }, { "start_pos": 2568, "end_pos": 2570 }, { "start_pos": 2584, "end_pos": 2586 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 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"https://www.omim.org/entry/172700", "name": "Pick disease of the brain", "description": "Pick disease of the brain" } ], "unlinked_id_list": [], "evidence": [ { "id": "11870", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11870" } ] }, { "disease_id": "DOID:1574", "recommended_name": { "id": "DOID:1574", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1574", "name": "alcohol use disorder", "description": "A substance abuse that involves the recurring use of alcoholic beverages despite negative consequences." }, "synonyms": [ { "id": "DOID:1574", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1574", "name": "Ethanol abuse", "description": "" }, { "id": "DOID:1574", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1574", "name": "alcohol abuse", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1574", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1574" } ] }, { "disease_id": "DOID:1596", "recommended_name": { "id": "DOID:1596", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1596", "name": "depressive disorder", "description": "A mood disorder characterized by persistent sadness, emptiness, or irritability and decreased ability to function." }, "synonyms": [ { "id": "DOID:1596", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1596", "name": "mental depression", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1596", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1596" } ] }, { "disease_id": "DOID:1826", "recommended_name": { "id": "DOID:1826", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1826", "name": "epilepsy", "description": "A brain disease that is characterized by the occurrance of at least two unprovoked seizures resulting from a persistent epileptogenic abnormality of the brain that is able to spontaneously generate paroxysmal activity and typically manifested by sudden brief episodes of altered or diminished consciousness, involuntary movements, or convulsions." }, "synonyms": [ { "id": "DOID:1826", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1826", "name": "epilepsy syndrome", "description": "" }, { "id": "DOID:1826", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1826", "name": "epileptic syndrome", "description": "" } ], "unlinked_id_list": [ "DOID:3331", "DOID:0050702", "DOID:0060172", "DOID:0050706", "DOID:0050705", "DOID:0050703", "DOID:0050701", "DOID:0060169" ], "evidence": [ { "id": "1826", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1826" } ] }, { "disease_id": "DOID:1984", "recommended_name": { "id": "DOID:1984", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1984", "name": "rectal benign neoplasm", "description": "An intestinal benign neoplasm located_in the rectum." }, "synonyms": [ { "id": "DOID:1984", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1984", "name": "Rectal tumor", "description": "" }, { "id": "DOID:1984", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1984", "name": "neoplasm of rectum", "description": "" }, { "id": "DOID:1984", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1984", "name": "rectum neoplasm", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1984", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1984" } ] }, { "disease_id": "DOID:2384", "recommended_name": { "id": "DOID:2384", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2384", "name": "Wernicke encephalopathy", "description": "A brain disease that is characterized by the presence of neurological symptoms of ophthalmoplegia, ataxia, and confusion caused by biochemical lesions of the central nervous system after exhaustion of B-vitamin reserves, in particular thiamine (vitamin B1)." }, "synonyms": [ { "id": "DOID:2384", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2384", "name": "Wernicke's disease", "description": "" }, { "id": "DOID:2384", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2384", "name": "Wernicke's encephalopathy", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2384", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2384" } ] }, { "disease_id": "DOID:2560", "recommended_name": { "id": "DOID:2560", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2560", "name": "morphine dependence", "description": "An opiate dependence that involves the continued use of morphine despite despite problems related to use of the substance." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "2560", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2560" } ] }, { "disease_id": "DOID:2921", "recommended_name": { "id": "DOID:2921", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2921", "name": "glomerulonephritis", "description": "A nephritis that causes inflammation of the glomeruli located_in kidney." }, "synonyms": [], "unlinked_id_list": [ "DOID:13138" ], "evidence": [ { "id": "2921", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2921" } ] }, { "disease_id": "DOID:3328", "recommended_name": { "id": "DOID:3328", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3328", "name": "temporal lobe epilepsy", "description": "A focal epilepsy that is characterized by recurrent, unprovoked focal seizures that originate in the temporal lobe of the brain and last about one or two minutes." }, "synonyms": [ { "id": "DOID:3328", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3328", "name": "epilepsy, temporal lobe", "description": "" }, { "id": "MONDO:0700090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700090", "name": "epilepsy, familial temporal lobe, 1", "description": "An autosomal dominant condition caused by mutation(s) in the LGI1 gene, encoding leucine-rich glioma-inactivated protein 1. It is characterized by partial seizures originating in the temporal lobe and often accompanied by auditory sensory manifestations." }, { "id": "MONDO:0700090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700090", "name": "ADLTE", "description": "" }, { "id": "MONDO:0700090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700090", "name": "ADPEAF", "description": "" }, { "id": "MONDO:0700090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700090", "name": "ETL1", "description": "" }, { "id": "MONDO:0700090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700090", "name": "epilepsy, familial temporal lobe, type 1", "description": "" }, { "id": "MONDO:0700090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700090", "name": "epilepsy, lateral temporal lobe, autosomal dominant", "description": "" }, { "id": "MONDO:0700090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700090", "name": "epilepsy, partial, with auditory features", "description": "" }, { "id": "MIM:600512", "resource": "MIM", "url": "https://www.omim.org/entry/600512", "name": "Epilepsy, familial temporal lobe, 1", "description": "Epilepsy, familial temporal lobe, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "3328", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3328" } ] }, { "disease_id": "DOID:3744", "recommended_name": { "id": "DOID:3744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3744", "name": "cervical squamous cell carcinoma", "description": "A cervix carcinoma that has_material_basis_in squamous cells of the cervix." }, "synonyms": [ { "id": "DOID:3744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3744", "name": "squamous cell carcinoma of cervix", "description": "" }, { "id": "DOID:3744", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3744", "name": "squamous cell carcinoma of the Cervix Uteri", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3744", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3744" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:6000", "recommended_name": { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "congestive heart failure", "description": "A heart disease that is characterized by any structural or functional cardiac disorder that impairs the ability of the heart to fill with or pump a sufficient amount of blood throughout the body." }, "synonyms": [ { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "CHF", "description": "" }, { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "Cardiac Failure Congestive", "description": "" }, { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "Congestive heart disease", "description": "" }, { "id": "DOID:6000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6000", "name": "Weak heart", "description": "" } ], "unlinked_id_list": [ "DOID:12326" ], "evidence": [ { "id": "6000", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6000" } ] }, { "disease_id": "DOID:6364", "recommended_name": { "id": "DOID:6364", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6364", "name": "migraine", "description": "A brain disease that is characterized by moderate to severe headaches, nausea, extreme sensitivity to light and sound and intense unilaterial throbbing or pulsing." }, "synonyms": [ { "id": "DOID:6364", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6364", "name": "migraine disorder", "description": "" }, { "id": "DOID:6364", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6364", "name": "migraine variant", "description": "" }, { "id": "DOID:6364", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:6364", "name": "migraine with or without aura", "description": "" }, { "id": "MONDO:0008000", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008000", "name": "migraine with or without aura, susceptibility to, 1", "description": "" }, { "id": "MONDO:0008000", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008000", "name": "migraine with or without aura, susceptibility to, 1", "description": "" }, { "id": "MONDO:0008000", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008000", "name": "migraine with or without aura, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0008000", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008000", "name": "migraine without aura, susceptibility to", "description": "" }, { "id": "MONDO:0008000", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008000", "name": "migraine, resistance to", "description": "" }, { "id": "MONDO:0008000", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008000", "name": "migraine, susceptibility to", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "6364", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:6364" } ] }, { "disease_id": "DOID:670", "recommended_name": { "id": "DOID:670", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:670", "name": "amphetamine abuse", "description": "A substance abuse that involves the recurring use of amphetamines despite negative consequences." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "670", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:670" } ] }, { "disease_id": "DOID:898", "recommended_name": { "id": "DOID:898", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:898", "name": "autosomal dominant polycystic kidney disease", "description": "A polycystic kidney disease characterized by the presence of multiple cysts located_in the kidney resulting from ciliopathy that disrupts the function of primary cilium, inherited in an autosomal dominant fashion." }, "synonyms": [ { "id": "DOID:898", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:898", "name": "Congenital biliary ectasias", "description": "" }, { "id": "DOID:898", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:898", "name": "POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1", "description": "" }, { "id": "DOID:898", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:898", "name": "ADPKD", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "898", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:898" } ] }, { "disease_id": "DOID:90", "recommended_name": { "id": "DOID:90", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:90", "name": "degenerative disc disease", "description": "A bone deterioration disease that has_material_basis_in gradual dehydration and tears located_in intervertebral disc." }, "synonyms": [ { "id": "DOID:90", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:90", "name": "cervical disc degenerative disease", "description": "" }, { "id": "DOID:90", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:90", "name": "intervertebral disc degeneration", "description": "" }, { "id": "DOID:90", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:90", "name": "lumbar disc degeneration", "description": "" }, { "id": "DOID:90", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:90", "name": "vertebral disc disease", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "intervertebral disk degenerative disorder", "description": "Any disease of a degenerative nature that affects the intervertebral disk." }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "IDD", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "degenerative disk disease", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "degenerative disorder of intervertebral disc", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "degenerative disorder of intervertebral disk", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "intervertebral Disc Degeneration", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "intervertebral Disc degenerative disease", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "intervertebral Disc degenerative disorder", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "intervertebral disc degeneration", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "intervertebral disc disease", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "intervertebral disk degeneration", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "intervertebral disk degenerative disorder", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "intervertebral disk disease", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "vertebral Disc degenerative disease", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "vertebral Disc degenerative disorder", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "vertebral disk disease", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "cervical disc degenerative disease", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "cervical disk degenerative disease", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "lumbar disc degeneration", "description": "" }, { "id": "MONDO:0011385", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011385", "name": "lumbar disk degeneration", "description": "" }, { "id": "MIM:603932", "resource": "MIM", "url": "https://www.omim.org/entry/603932", "name": "Intervertebral disc disease", "description": "Intervertebral disc disease" } ], "unlinked_id_list": [], "evidence": [ { "id": "90", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:90" } ] }, { "disease_id": "DOID:9408", "recommended_name": { "id": "DOID:9408", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9408", "name": "acute myocardial infarction", "description": "" }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "9408", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9408" } ] }, { "disease_id": "DOID:9778", "recommended_name": { "id": "DOID:9778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9778", "name": "irritable bowel syndrome", "description": "An intestinal disease that is characterized by chronic abdominal pain, discomfort, bloating, and alteration of bowel habits in the absence of any detectable organic cause." }, "synonyms": [ { "id": "DOID:9778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9778", "name": "IBD", "description": "" }, { "id": "DOID:9778", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9778", "name": "Irritable colon", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9778", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9778" } ] }, { "disease_id": "DOID:9975", "recommended_name": { "id": "DOID:9975", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0S1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fosaa", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131121-552", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-552", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P0S1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P0S1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14721", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14721", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "570238", "url": "https://www.ncbi.nlm.nih.gov/gene/570238", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570238", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570238", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P0S1", "url": "https://www.orthodb.org/?gene=A0A8M9P0S1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23351:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23351:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00170", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00170", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323167", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323167", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P0S1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P0S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131121-552", "url": "https://zfin.org/ZDB-GENE-131121-552", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MQLFIEKNKPIEESPQRLCVSIDVRDNAKRNLLCPSRSQGESPGAFVPTVTAISSTPDLQWMVQPTIITSVSPSQGRTDSNEPAKSKPAGNKGKCAARKSKSEQLSPEEEEKKRIRRERNKMAAAKCRNRRRELTDTLQAETDKLEEDKAALQAEIESLLKEKERLEYVLASHKPLCQMPEELDCLFPESPQPLPAPESSSKLPEDSPQDAASLQDLEIPTVPSSAISGNSNILLCSSAEVSLCDLEPSLDVRDELLAGSGGDDDRVSARSVPDIDLSGSLGITDWETLYKSVANDLEPLSTPVVSTSTPTCSNYLSVFTFACPELDSLAEGLDVCKCGVTKAESSVDILNSPTLLAL", "length": 358, "header": "tr|A0A8M9P0S1-1|A0A8M9P0S1_DANRE Isoform 1 of Protein c-Fos OS=Danio rerio OX=7955 GN=fosaa PE=4 SV=1 CANONICAL=A0A8M9P0S1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P0S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S1/entry#A0A8M9P0S1-1", "sequence": { "sequence": "MQLFIEKNKPIEESPQRLCVSIDVRDNAKRNLLCPSRSQGESPGAFVPTVTAISSTPDLQWMVQPTIITSVSPSQGRTDSNEPAKSKPAGNKGKCAARKSKSEQLSPEEEEKKRIRRERNKMAAAKCRNRRRELTDTLQAETDKLEEDKAALQAEIESLLKEKERLEYVLASHKPLCQMPEELDCLFPESPQPLPAPESSSKLPEDSPQDAASLQDLEIPTVPSSAISGNSNILLCSSAEVSLCDLEPSLDVRDELLAGSGGDDDRVSARSVPDIDLSGSLGITDWETLYKSVANDLEPLSTPVVSTSTPTCSNYLSVFTFACPELDSLAEGLDVCKCGVTKAESSVDILNSPTLLAL", "length": 358, "header": "tr|A0A8M9P0S1-1|A0A8M9P0S1_DANRE Isoform 1 of Protein c-Fos OS=Danio rerio OX=7955 GN=fosaa PE=4 SV=1 CANONICAL=A0A8M9P0S1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:570238", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570238", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3AHY8-1", "protein_name": "Fos-related antigen 1a isoform X1", "gene_name": "fosl1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYNYGNPGRGIDRSFPESSSGSSGSSSASVATTTGTTQQQQQKYSVAGSGQFVPSLNAITSNQSLQWMLQPSIGTPGPSRALRSSYPLPPGIPATMNPPQPSQSHLSRPGVIRAAAAIGSTTRRNDEYLSPEELERRRIRRERNKMAAAKCRNRRRELTDTLQNETDQLEDEKSRLQKEIADLQKEKEKLELVFEAHRPICKVQESESDSDSSNDIPSLSGIKIEPVDPDLPGPSRETKHYAKINKPKPKITIPPPPSASSITGIPLESESLHTPVLISTPSLTPFTASLVFSYPSTSLDTSSQALNLVTSHPSSQNPQPCAVAHRRSSSSGDQSDHSLNSPTILTL", "length": 347 }, "evidence": [ { "id": "FB:FBgn0001297", "url": "https://alliancegenome.org/gene/FB:FBgn0001297#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LUR3-1", "protein_name": "FOS like 1, AP-1 transcription factor subunit", "gene_name": "Fosl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYRDFGEPGPSSGAGSAYGRPAQPQQAQTQTVQQQFHLVPSINAVSGSQELQWMVQPHFLGPSGYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEEDKKDTGGTSSTSGAGSPPGPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPSTPEPCSSAHRKSSSSSGDPSSDPLGSPTLLAL", "length": 274 }, "evidence": [ { "id": "FB:FBgn0001297", "url": "https://alliancegenome.org/gene/FB:FBgn0001297#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P01100-1", "protein_name": "Protein c-Fos", "gene_name": "FOS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNAQDFCTDLAVSSANFIPTVTAISTSPDLQWLVQPALVSSVAPSQTRAPHPFGVPAPSAGAYSRAGVVKTMTGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEVATPESEEAFTLPLLNDPEPKPSVEPVKSISSMELKTEPFDDFLFPASSRPSGSETARSVPDMDLSGSFYAADWEPLHSGSLGMGPMATELEPLCTPVVTCTPSCTAYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL", "length": 380 }, "evidence": [ { "id": "HGNC:3796", "url": "https://alliancegenome.org/gene/HGNC:3796#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-552", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-552#orthology", "database": "AGR" }, { "id": "MGI:95574", "url": "https://alliancegenome.org/gene/MGI:95574#orthology", "database": "AGR" }, { "id": "RGD:2626", "url": "https://alliancegenome.org/gene/RGD:2626#orthology", "database": "AGR" }, { "id": "FB:FBgn0001297", "url": "https://alliancegenome.org/gene/FB:FBgn0001297#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P01101-1", "protein_name": "Protein c-Fos", "gene_name": "Fos", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANFIPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGLPTQSAGAYARAGMVKTVSGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPDDLGFPEEMSVASLDLTGGLPEASTPESEEAFTLPLLNDPEPKPSLEPVKSISNVELKAEPFDDFLFPASSRPSGSETSRSVPDVDLSGSFYAADWEPLHSNSLGMGPMVTELEPLCTPVVTCTPGCTTYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL", "length": 380 }, "evidence": [ { "id": "HGNC:3796", "url": "https://alliancegenome.org/gene/HGNC:3796#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-552", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-552#orthology", "database": "AGR" }, { "id": "MGI:95574", "url": "https://alliancegenome.org/gene/MGI:95574#orthology", "database": "AGR" }, { "id": "RGD:2626", "url": "https://alliancegenome.org/gene/RGD:2626#orthology", "database": "AGR" }, { "id": "FB:FBgn0001297", "url": "https://alliancegenome.org/gene/FB:FBgn0001297#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P12841-1", "protein_name": "Protein c-Fos", "gene_name": "Fos", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMFSGFNADYEASSSRCSSASPAGDSLSYYHSPADSFSSMGSPVNTQDFCADLSVSSANFIPTVTAISTSPDLQWLVQPTLVSSVAPSQTRAPHPYGLPTPSTGAYARAGVVKTMSGGRAQSIGRRGKVEQLSPEEEEKRRIRRERNKMAAAKCRNRRRELTDTLQAETDQLEDEKSALQTEIANLLKEKEKLEFILAAHRPACKIPNDLGFPEEMSVTSLDLTGGLPEATTPESEEAFTLPLLNDPEPKPSLEPVKNISNMELKAEPFDDFLFPASSRPSGSETARSVPDVDLSGSFYAADWEPLHSSSLGMGPMVTELEPLCTPVVTCTPSCTTYTSSFVFTYPEADSFPSCAAAHRKGSSSNEPSSDSLSSPTLLAL", "length": 380 }, "evidence": [ { "id": "HGNC:3796", "url": "https://alliancegenome.org/gene/HGNC:3796#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-552", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-552#orthology", "database": "AGR" }, { "id": "MGI:95574", "url": "https://alliancegenome.org/gene/MGI:95574#orthology", "database": "AGR" }, { "id": "RGD:2626", "url": "https://alliancegenome.org/gene/RGD:2626#orthology", "database": "AGR" }, { "id": "FB:FBgn0001297", "url": "https://alliancegenome.org/gene/FB:FBgn0001297#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P15407-1", "protein_name": "Fos-related antigen 1", "gene_name": "FOSL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFRDFGEPGPSSGNGGGYGGPAQPPAAAQAAQQKFHLVPSINTMSGSQELQWMVQPHFLGPSSYPRPLTYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGAKEGDTGSTSGTSSPPAPCRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPSTPEPCASAHRKSSSSSGDPSSDPLGSPTLLAL", "length": 271 }, "evidence": [ { "id": "FB:FBgn0001297", "url": "https://alliancegenome.org/gene/FB:FBgn0001297#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P15408-1", "protein_name": "Fos-related antigen 2", "gene_name": "FOSL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPAPGLQPMRSGGGSVGAVVVKQEPLEEDSPSSSSAGLDKAQRSVIKPISIAGGFYGEEPLHTPIVVTSTPAVTPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL", "length": 326 }, "evidence": [ { "id": "FB:FBgn0001297", "url": "https://alliancegenome.org/gene/FB:FBgn0001297#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P21525-5", "protein_name": "Transcription factor kayak, isoforms A/B/F", "gene_name": "kay", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKNLNGRTHNACYHPYYHQSLHFAQQQQQQQQHHLQQQQQHMQQQQQQQQAPQQQLRHQQRQLPTQPAYQQSQSVAHNAFPLRSSSNNYGHVASSAYAASSGSHNSNNAAAMAAVCQMQNFFNQQQQQQQQLEFNNNCMPINYYQQQQQQHYPSESQSSASGWNPETPGQAQLALTATTCNTTAAATCNTTAAATTSTTATSAAAGSDNNHSDNFAMDASEIATFLANELFLQQLGNFETGQSVLTLTTPTLTPTTTRNIEDTLGHLLSDTQTDRVAGCAGFAVPKVLPNAIDVLGMGIPTGVSSLPLQQTFDLSLGQGSESEDSNASYNDTQMNEEQDTTDTSSAHTDSTSYQAGHIMAGSVNGGGVNNFSNVLAAVSSSRGSASVGSSNANTSNTPARRGGGRRPNRSTNMTPEEEQKRAVRRERNKQAAARCRKRRVDQTNELTEEVEQLEKRGESMRKEIEVLTNSKNQLEYLLATHRATCQKIRSDMLSVVTCNGLIAPAGLLSAGSSGSGASSHHNHNSNDSSNGTITGMDATLNSTGRSNSPLDLKPAANIDSLLMHIKDEPLDGAIDSGSSLDQDGPPPSKRITLPPMSTMPHVHLSTILTPTGASSGSLQTPITSTAPGGFGSAFPVTSNGSSINNINSIGNNMNSPTLNAHNKVPKERPNTLAFQRPLGQMHLTMANNKAGGPTQIQGVPIQTPSTGTFNFDSLMDGGTGLTPVSGPLVPNSSSTNKHPLELPTPTAEPSKLVSL", "length": 755 }, "evidence": [ { "id": "HGNC:3796", "url": "https://alliancegenome.org/gene/HGNC:3796#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-552", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-552#orthology", "database": "AGR" }, { "id": "MGI:95574", "url": "https://alliancegenome.org/gene/MGI:95574#orthology", "database": "AGR" }, { "id": "RGD:2626", "url": "https://alliancegenome.org/gene/RGD:2626#orthology", "database": "AGR" }, { "id": "FB:FBgn0001297", "url": "https://alliancegenome.org/gene/FB:FBgn0001297#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P47930-1", "protein_name": "Fos-related antigen 2", "gene_name": "Fosl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPTSGLQSLRGTGSAVGPVVVKQEPPEEDSPSSSAGMDKTQRSVIKPISIAGGGFYGEEPLHTPIVVTSTPAITPGTSNLVFTYPNVLEQESPSSPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL", "length": 326 }, "evidence": [ { "id": "FB:FBgn0001297", "url": "https://alliancegenome.org/gene/FB:FBgn0001297#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P48755-1", "protein_name": "Fos-related antigen 1", "gene_name": "Fosl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYRDYGEPGPSSGAGSPYGRPAQPPQAQAQTAQQQKFHLVPSIDSSSQELHWMVQPHFLGPTGYPRPLAYPQYSPPQPRPGVIRALGPPPGVRRRPCEQISPEEEERRRVRRERNKLAAAKCRNRRKELTDFLQAETDKLEDEKSGLQREIEELQKQKERLELVLEAHRPICKIPEGDKKDPGGSGSTSGASSPPAPGRPVPCISLSPGPVLEPEALHTPTLMTTPSLTPFTPSLVFTYPSTPEPCSSAHRKSSSSSGDPSSDPLGSPTLLAL", "length": 273 }, "evidence": [ { "id": "FB:FBgn0001297", "url": "https://alliancegenome.org/gene/FB:FBgn0001297#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P51145-1", "protein_name": "Fos-related antigen 2", "gene_name": "Fosl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYQDYPGNFDTSSRGSSGSPAHAESYSSGGGGQQKFRVDMPGSGSAFIPTINAITTSQDLQWMVQPTVITSMSNPYPRSHPYSPLPGLASVPGHMALPRPGVIKTIGTTVGRRRRDEQLSPEEEEKRRIRRERNKLAAAKCRNRRRELTEKLQAETEELEEEKSGLQKEIAELQKEKEKLEFMLVAHGPVCKISPEERRSPPTSGLQSLRGTGSAVGPVVVKQEPPEEDSPSSSAGMDKTQRSVIKPISIAGGGFYGEEPLHTPIVVTSTPAITPGTSNLVFTYPSVLEQESPASPSESCSKAHRRSSSSGDQSSDSLNSPTLLAL", "length": 326 }, "evidence": [ { "id": "FB:FBgn0001297", "url": "https://alliancegenome.org/gene/FB:FBgn0001297#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0S1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0S1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0S1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S1" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P0S1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P0S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P0S1" }, { "id": "PS50217", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50217" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BZIP", "eco_id": "ECO_0000259", "start_pos": 110, "end_pos": 173, "start_aa": "Glu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P186-1", "uniprot_ac": "A0A8M9P186", "uniprot_id": "A0A8M9P186_DANRE", "mass": { "chemical_mass": 99544.0, "monoisotopic_mass": 99544.0 }, "refseq": { "ac": "XP_021323417", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323417" }, "gene_names": [ { "name": "LOC100537321", "type": "recommended", "evidence": [ { "id": "A0A8M9P186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ] }, { "name": "LOC100537321", "type": "synonym", "evidence": [ { "id": "XP_021323417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323417" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323417" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323417" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100537321", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186", "locus": {} } ], "crossref": [ { "id": "A0A8M9P186", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P186", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd11304", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11304", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100537321", "url": "https://www.ncbi.nlm.nih.gov/gene/100537321", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002126", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002126", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039808", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039808", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100537321", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100537321", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P186", "url": "https://www.orthodb.org/?gene=A0A8M9P186", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24027:SF431", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24027:SF431", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323417", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P186-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PAA1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PAA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFN7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HWH4", "url": "https://www.uniprot.org/uniprotkb/A0AC58HWH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HWH4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HWH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HWI4", "url": "https://www.uniprot.org/uniprotkb/A0AC58HWI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HWI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HWI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HWK1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HWK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HWK1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HWK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HWK2", "url": "https://www.uniprot.org/uniprotkb/A0AC58HWK2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HWK2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HWK2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HWK6", "url": "https://www.uniprot.org/uniprotkb/A0AC58HWK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HWK6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HWK6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVLRLIFRKQPLWRILIFCHLYSAVSRNSVIAASECEGGHDVFAKVKENSLMGTFIANLSFTADPSAHRMHLRLSGKDAGWFYLEGKTIRLNSTSTRIIDREKHGSVLKATVRCYEHKVLQAELRIMVEVLDENDNKPEFLQSSTQPVQLSELTAVNSVVFTVQATDADGDTLTYIIEESSPDARYFRVDLPNSGKVILNKSLDYEIKTQLRLTLYAVETNTKEHYNTTATVIINVTDGDDQYPQFQPCTLLSANHSKRICANPLYTANITENEQDIVLDFFPGPIQAVDGDEGLRTPIKYTILSGADNGRFVIDSSSGEVRLTRCVKNRLLIPTLRLRVMAAQTDDPLKYAVATVLVRVLAENKFPPQFSRSAYRGFVSESTSPASLVMTYANKLLILEATDQDFTNGFNPRLQYSLNSQINSSRLFYITQEALLIAKTSQLHPGHKYFLEVLATDLESGDTVKATLHVEVLQRGQTVPQGPLGVGYPYSRETVGRAEGVAGVCLILLAITLFTVVRCIRMSREKRDHVIRNTVADSTHPNVKLRWFQMVNHSAPMPLMEDTFSRHNEAFSEYDYSTSPFYGKQGIYTKTEEPPPSSSSSAANLPSITFNKSLLKEPRRNYLALRPNGRPVHRFNNKTVSFQDYVVVRECDEESEETTTFTTEVEVCSDFEEINMDYGLENGDSDVTEELEIQSPTSYCDDASEMLNTQVDQDYETAIANQTDSEDIHADPPQKVSGIHRIKSDLEKIHRDSTLTPERDHSPSQKTHSEDAAFSSFKGESQIINTKALVSYKHSENVQSDCVRQSDDLTVDAVVSGAESSVQNTQDASNFTADLQTHDSYYINEDIATNLDDSSPGEQSGSSSDSSSQQLNYLQVLQFFDKHLDDDGD", "length": 889, "header": "tr|A0A8M9P186-1|A0A8M9P186_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100537321 PE=4 SV=1 CANONICAL=A0A8M9P186-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P186-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186/entry#A0A8M9P186-1", "sequence": { "sequence": "MVLRLIFRKQPLWRILIFCHLYSAVSRNSVIAASECEGGHDVFAKVKENSLMGTFIANLSFTADPSAHRMHLRLSGKDAGWFYLEGKTIRLNSTSTRIIDREKHGSVLKATVRCYEHKVLQAELRIMVEVLDENDNKPEFLQSSTQPVQLSELTAVNSVVFTVQATDADGDTLTYIIEESSPDARYFRVDLPNSGKVILNKSLDYEIKTQLRLTLYAVETNTKEHYNTTATVIINVTDGDDQYPQFQPCTLLSANHSKRICANPLYTANITENEQDIVLDFFPGPIQAVDGDEGLRTPIKYTILSGADNGRFVIDSSSGEVRLTRCVKNRLLIPTLRLRVMAAQTDDPLKYAVATVLVRVLAENKFPPQFSRSAYRGFVSESTSPASLVMTYANKLLILEATDQDFTNGFNPRLQYSLNSQINSSRLFYITQEALLIAKTSQLHPGHKYFLEVLATDLESGDTVKATLHVEVLQRGQTVPQGPLGVGYPYSRETVGRAEGVAGVCLILLAITLFTVVRCIRMSREKRDHVIRNTVADSTHPNVKLRWFQMVNHSAPMPLMEDTFSRHNEAFSEYDYSTSPFYGKQGIYTKTEEPPPSSSSSAANLPSITFNKSLLKEPRRNYLALRPNGRPVHRFNNKTVSFQDYVVVRECDEESEETTTFTTEVEVCSDFEEINMDYGLENGDSDVTEELEIQSPTSYCDDASEMLNTQVDQDYETAIANQTDSEDIHADPPQKVSGIHRIKSDLEKIHRDSTLTPERDHSPSQKTHSEDAAFSSFKGESQIINTKALVSYKHSENVQSDCVRQSDDLTVDAVVSGAESSVQNTQDASNFTADLQTHDSYYINEDIATNLDDSSPGEQSGSSSDSSSQQLNYLQVLQFFDKHLDDDGD", "length": 889, "header": "tr|A0A8M9P186-1|A0A8M9P186_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100537321 PE=4 SV=1 CANONICAL=A0A8M9P186-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PAA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186/entry#A0A8M9PAA1-1", "sequence": { "sequence": "MVLRLIFRKQPLWRILIFCHLYSAVSRNSVIASECEGGHDVFAKVKENSLMGTFIANLSFTADPSAHRMHLRLSGKDAGWFYLEGKTIRLNSTSTRIIDREKHGSVLKATVRCYEHKVLQAELRIMVEVLDENDNKPEFLQSSTQPVQLSELTAVNSVVFTVQATDADGDTLTYIIEESSPDARYFRVDLPNSGKVILNKSLDYEIKTQLRLTLYAVETNTKEHYNTTATVIINVTDGDDQYPQFQPCTLLSANHSKRICANPLYTANITENEQDIVLDFFPGPIQAVDGDEGLRTPIKYTILSGADNGRFVIDSSSGEVRLTRCVKNRLLIPTLRLRVMAAQTDDPLKYAVATVLVRVLAENKFPPQFSRSAYRGFVSESTSPASLVMTYANKLLILEATDQDFTNGFNPRLQYSLNSQINSSRLFYITQEALLIAKTSQLHPGHKYFLEVLATDLESGDTVKATLHVEVLQRGQTVPQGPLGVGYPYSRETVGRAEGVAGVCLILLAITLFTVVRCIRMSREKRDHVIRNTVADSTHPNVKLRWFQMVNHSAPMPLMEDTFSRHNEAFSEYDYSTSPFYGKQGIYTKTEEPPPSSSSSAANLPSITFNKSLLKEPRRNYLALRPNGRPVHRFNNKTVSFQDYVVVRECDEESEETTTFTTEVEVCSDFEEINMDYGLENGDSDVTEELEIQSPTSYCDDASEMLNTQVDQDYETAIANQTDSEDIHADPPQKVSGIHRIKSDLEKIHRDSTLTPERDHSPSQKTHSEDAAFSSFKGESQIINTKALVSYKHSENVQSDCVRQSDDLTVDAVVSGAESSVQNTQDASNFTADLQTHDSYYINEDIATNLDDSSPGEQSGSSSDSSSQQLNYLQVLQFFDKHLDDDGD", "length": 888, "header": "tr|A0A8M9PAA1-1|A0A8M9PAA1_DANRE Computationally mapped isoform of Cadherin-related family member 5 isoform X2 OS=Danio rerio OX=7955 GN=LOC100537321 PE=4 SV=1 CANONICAL=A0A8M9P186-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PFN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186/entry#A0A8M9PFN7-1", "sequence": { "sequence": "MVLRLIFRKQPLWRILIFCHLYSAVSRNSVIAASECEGGHDVFAKVKENSLMGTFIANLSFTADPSAHRMHLRLSGKDAGWFYLEGKTIRLNSTSTRIIDREKHGSVLKATVRCYEHKVLQAELRIMVEVLDENDNKPEFLQSSTQPVQLSEETNTKEHYNTTATVIINVTDGDDQYPQFQPCTLLSANHSKRICANPLYTANITENEQDIVLDFFPGPIQAVDGDEGLRTPIKYTILSGADNGRFVIDSSSGEVRLTRCVKNRLLIPTLRLRVMAAQTDDPLKYAVATVLVRVLAENKFPPQFSRSAYRGFVSESTSPASLVMTYANKLLILEATDQDFTNGFNPRLQYSLNSQINSSRLFYITQEALLIAKTSQLHPGHKYFLEVLATDLESGDTVKATLHVEVLQRGQTVPQGPLGVGYPYSRETVGRAEGVAGVCLILLAITLFTVVRCIRMSREKRDHVIRNTVADSTHPNVKLRWFQMVNHSAPMPLMEDTFSRHNEAFSEYDYSTSPFYGKQGIYTKTEEPPPSSSSSAANLPSITFNKSLLKEPRRNYLALRPNGRPVHRFNNKTVSFQDYVVVRECDEESEETTTFTTEVEVCSDFEEINMDYGLENGDSDVTEELEIQSPTSYCDDASEMLNTQVDQDYETAIANQTDSEDIHADPPQKVSGIHRIKSDLEKIHRDSTLTPERDHSPSQKTHSEDAAFSSFKGESQIINTKALVSYKHSENVQSDCVRQSDDLTVDAVVSGAESSVQNTQDASNFTADLQTHDSYYINEDIATNLDDSSPGEQSGSSSDSSSQQLNYLQVLQFFDKHLDDDGD", "length": 823, "header": "tr|A0A8M9PFN7-1|A0A8M9PFN7_DANRE Computationally mapped isoform of Uncharacterized protein isoform X4 OS=Danio rerio OX=7955 GN=LOC100537321 PE=4 SV=1 CANONICAL=A0A8M9P186-1" }, "locus": {} }, { "isoform_ac": "A0AC58HWH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186/entry#A0AC58HWH4-1", "sequence": { "sequence": "MVLRLIFRKQPLWRILIFCHLYSAVSRNSVIASECEGGHDVFAKVKENSLMGTFIANLSFTADPSAHRMHLRLSGKDAGWFYLEGKTIRLNSTSTRIIDREKHGSVLKATVRCYEHKVLQAELRIMVEVLDENDNKPEFLQSSTQPVQLSEETNTKEHYNTTATVIINVTDGDDQYPQFQPCTLLSANHSKRICANPLYTANITENEQDIVLDFFPGPIQAVDGDEGLRTPIKYTILSGADNGRFVIDSSSGEVRLTRCVKNRLLIPTLRLRVMAAQTDDPLKYAVATVLVRVLAENKFPPQFSRSAYRGFVSESTSPASLVMTYANKLLILEATDQDFTNGFNPRLQYSLNSQINSSRLFYITQEALLIAKTSQLHPGHKYFLEVLATDLESGDTVKATLHVEVLQRGQTVPQGPLGVGYPYSRETVGRAEGVAGVCLILLAITLFTVVRCIRMSREKRDHVIRNTVADSTHPNVKLRWFQMVNHSAPMPLMEDTFSRHNEAFSEYDYSTSPFYGKQGIYTKTEEPPPSSSSSAANLPSITFNKSLLKEPRRNYLALRPNGRPVHRFNNKTVSFQDYVVVRECDEESEETTTFTTEVEVCSDFEEINMDYGLENGDSDVTEELEIQSPTSYCDDASEMLNTQVDQDYETAIANQTDSEDIHADPPQKVSGIHRIKSDLEKIHRDSTLTPERDHSPSQKTHSEDAAFSSFKGESQIINTKALVSYKHSENVQSDCVRQSDDLTVDAVVSGAESSVQNTQDASNFTADLQTHDSYYINEDIATNLDDSSPGEQSGSSSDSSSQQLNYLQVLQFFDKHLDDDGD", "length": 822, "header": "tr|A0AC58HWH4-1|A0AC58HWH4_DANRE Computationally mapped isoform of Uncharacterized protein isoform X5 OS=Danio rerio OX=7955 GN=LOC100537321 PE=4 SV=1 CANONICAL=A0A8M9P186-1" }, "locus": {} }, { "isoform_ac": "A0AC58HWI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186/entry#A0AC58HWI4-1", "sequence": { "sequence": "MGTFIANLSFTADPSAHRMHLRLSGKDAGWFYLEGKTIRLNSTSTRIIDREKHGSVLKATVRCYEHKVLQAELRIMVEVLDENDNKPEFLQSSTQPVQLSELTAVNSVVFTVQATDADGDTLTYIIEESSPDARYFRVDLPNSGKVILNKSLDYEIKTQLRLTLYAVETNTKEHYNTTATVIINVTDGDDQYPQFQPCTLLSANHSKRICANPLYTANITENEQDIVLDFFPGPIQAVDGDEGLRTPIKYTILSGADNGRFVIDSSSGEVRLTRCVKNRLLIPTLRLRVMAAQTDDPLKYAVATVLVRVLAENKFPPQFSRSAYRGFVSESTSPASLVMTYANKLLILEATDQDFTNGFNPRLQYSLNSQINSSRLFYITQEALLIAKTSQLHPGHKYFLEVLATDLESGDTVKATLHVEVLQRGQTVPQGPLGVGYPYSRETVGRAEGVAGVCLILLAITLFTVVRCIRMSREKRDHVIRNTVADSTHPNVKLRWFQMVNHSAPMPLMEDTFSRHNEAFSEYDYSTSPFYGKQGIYTKTEEPPPSSSSSAANLPSITFNKSLLKEPRRNYLALRPNGRPVHRFNNKTVSFQDYVVVRECDEESEETTTFTTEVEVCSDFEEINMDYGLENGDSDVTEELEIQSPTSYCDDASEMLNTQVDQDYETAIANQTDSEDIHADPPQKVSGIHRIKSDLEKIHRDSTLTPERDHSPSQKTHSEDAAFSSFKGESQIINTKALVSYKHSENVQSDCVRQSDDLTVDAVVSGAESSVQNTQDASNFTADLQTHDSYYINEDIATNLDDSSPGEQSGSSSDSSSQQLNYLQVLQFFDKHLDDDGD", "length": 838, "header": "tr|A0AC58HWI4-1|A0AC58HWI4_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=LOC100537321 PE=4 SV=1 CANONICAL=A0A8M9P186-1" }, "locus": {} }, { "isoform_ac": "A0AC58HWK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186/entry#A0AC58HWK1-1", "sequence": { "sequence": "MCEEQTADPDTETTSYAQTDDPLKYAVATVLVRVLAENKFPPQFSRSAYRGFVSESTSPASLVMTYANKLLILEATDQDFTNGFNPRLQYSLNSQINSSRLFYITQEALLIAKTSQLHPGHKYFLEVLATDLESGDTVKATLHVEVLQRGQTVPQGPLGVGYPYSRETVGRAEGVAGVCLILLAITLFTVVRCIRMSREKRDHVIRNTVADSTHPNVKLRWFQMVNHSAPMPLMEDTFSRHNEAFSEYDYSTSPFYGKQGIYTKTEEPPPSSSSSAANLPSITFNKSLLKEPRRNYLALRPNGRPVHRFNNKTVSFQDYVVVRECDEESEETTTFTTEVEVCSDFEEINMDYGLENGDSDVTEELEIQSPTSYCDDASEMLNTQVDQDYETAIANQTDSEDIHADPPQKVSGIHRIKSDLEKIHRDSTLTPERDHSPSQKTHSEDAAFSSFKGESQIINTKALVSYKHSENVQSDCVRQSDDLTVDAVVSGAESSVQNTQDASNFTADLQTHDSYYINEDIATNLDDSSPGEQSGSSSDSSSQQLNYLQVLQFFDKHLDDDGD", "length": 563, "header": "tr|A0AC58HWK1-1|A0AC58HWK1_DANRE Computationally mapped isoform of Uncharacterized protein isoform X7 OS=Danio rerio OX=7955 GN=LOC100537321 PE=4 SV=1 CANONICAL=A0A8M9P186-1" }, "locus": {} }, { 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OS=Danio rerio OX=7955 GN=LOC100537321 PE=4 SV=1 CANONICAL=A0A8M9P186-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100537321", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100537321", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" }, { "name": "catenin complex", "id": "GO:0016342", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016342", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 8, "go_terms": [ { "name": "cell migration", "id": "GO:0016477", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016477", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" }, { "name": "cell morphogenesis", "id": "GO:0000902", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000902", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" }, { "name": "cell-cell junction assembly", "id": "GO:0007043", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007043", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" }, { "name": "homophilic cell adhesion via plasma membrane adhesion molecules", "id": "GO:0007156", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007156", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" }, { "name": "adherens junction organization", "id": "GO:0034332", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034332", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" }, { "name": "calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules", "id": "GO:0016339", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016339", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" }, { "name": "cell-cell adhesion mediated by cadherin", "id": "GO:0044331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044331", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" }, { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" }, { "name": "cadherin binding", "id": "GO:0045296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045296", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" }, { "name": "beta-catenin binding", "id": "GO:0008013", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008013", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P186", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 235, "end_pos": 237, "annotation": "n_glycosylation_sequon" }, { "start_pos": 255, "end_pos": 257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 269, "end_pos": 271, "annotation": "n_glycosylation_sequon" }, { "start_pos": 423, "end_pos": 425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 637, "end_pos": 639, "annotation": "n_glycosylation_sequon" }, { "start_pos": 721, "end_pos": 723, "annotation": "n_glycosylation_sequon" }, { "start_pos": 830, "end_pos": 832, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P186", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P186" }, { "id": "PS50268", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50268" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cadherin", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 140, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 200, "end_pos": 202 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 235, "end_pos": 237 }, { "start_pos": 255, "end_pos": 257 }, { "start_pos": 269, "end_pos": 271 }, { "start_pos": 423, "end_pos": 425 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 58, "end_pos": 60 }, { "start_pos": 611, "end_pos": 613 }, { "start_pos": 637, "end_pos": 639 }, { "start_pos": 721, "end_pos": 723 }, { "start_pos": 830, "end_pos": 832 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PG27-1", "uniprot_ac": "A0A8M9PG27", "uniprot_id": "A0A8M9PG27_DANRE", "mass": { "chemical_mass": 86881.0, "monoisotopic_mass": 86881.0 }, "refseq": { "ac": "XP_021323594", "name": "kin of IRRE-like protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323594" }, "gene_names": [ { "name": "kirrel3b", "type": "recommended", "evidence": [ { "id": "A0A8M9PG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27" } ] }, { "name": "kirrel3b", "type": "synonym", "evidence": [ { "id": "XP_021323594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323594" } ] } ], "protein_names": [ { "name": "Kin of IRRE-like protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27/entry#names_and_taxonomy" } ] }, { "name": "kin of IRRE-like protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323594", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323594" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323594", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323594" } ] } ], "disease": [ { "disease_id": "DOID:1184", "recommended_name": { "id": "DOID:1184", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1184", "name": "nephrotic syndrome", "description": "A nephrosis characterized by marked increase in glomerular protein permeability resulting in marked elevation of urine protein levels, hypoalbuminemia, hyperlipidemia, and hypercoagulability." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "1184", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1184" } ] }, { "disease_id": "DOID:557", "recommended_name": { "id": "DOID:557", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:557", "name": "kidney disease", "description": "A urinary system disease that is located_in the kidney." }, "synonyms": [ { "id": "DOID:557", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:557", "name": "nephropathy", "description": "" }, { "id": "DOID:557", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:557", "name": "impaired renal function disease", "description": "" } ], "unlinked_id_list": [ "DOID:0081055", "DOID:3116", "DOID:13138", "DOID:3675", "DOID:4455", "DOID:0080616", "DOID:2744", "DOID:9808", "DOID:582" ], "evidence": [ { "id": "557", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:557" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG27", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "kirrel3b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100713-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100713-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PG27", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PG27", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05759", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05759", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05898", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05898", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "572369", "url": "https://www.ncbi.nlm.nih.gov/gene/572369", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051275", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051275", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:572369", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:572369", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PG27", "url": "https://www.orthodb.org/?gene=A0A8M9PG27", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11640", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11640", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11640:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11640:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08205", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08205", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323594", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323594", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P1K3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P1K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P1K3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PAN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PAN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PG27", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PG27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PG29", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PG29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PMU4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PMU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PR41", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PR41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PR41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PR41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PR44", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PR44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PR44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PR44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HV06", "url": "https://www.uniprot.org/uniprotkb/A0AC58HV06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HV06-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HV06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HV23", "url": "https://www.uniprot.org/uniprotkb/A0AC58HV23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HV23-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HV23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HV51", "url": "https://www.uniprot.org/uniprotkb/A0AC58HV51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HV51-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HV51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100713-3", "url": "https://zfin.org/ZDB-GENE-100713-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPERSPPRRVKMILEVFLILWLTGHGVNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQAIQAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVEPQPVLEGNLVKFHCSAKANPPVTQYKWAKGGSVIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQGGSQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRKKSAHLCTEDAHLVMPTLPTSICAQQRELASKIKTENLKGVVSAKNDIRVEIVHKDHNAARESEEHSGMKQLMIERGEFQQESVLKQLEVLQEEEKEYQHIKDPTNGYYSVNTFKEHHGTPTTMAGNQTTELRRDPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSKASASSSSHYSQSSSQNSDLTRPLQKRMQTHV", "length": 795, "header": "tr|A0A8M9PG27-1|A0A8M9PG27_DANRE Isoform 1 of Kin of IRRE-like protein 3 isoform X1 OS=Danio rerio OX=7955 GN=kirrel3b PE=3 SV=1 CANONICAL=A0A8M9PG27-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P1K3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27/entry#A0A8M9P1K3-1", "sequence": { "sequence": "MPERSPPRRVKMILEVFLILWLTGHGVNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQAIQAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVEPQPVLEGNLVKFHCSAKANPPVTQYKWAKGGSVIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQGGSQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRKDAHLVMPTLPTSICAQQRELASKIKTENLKGVVSAKNDIRVEIVHKDHNAARESEEHSGMKQLMIERGEFQQESVLKQLEVLQEEEKEYQHIKDPTNGYYSVNTFKEHHGTPTTMAGNQTTELRRDPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSKASASSSSHYSQSSSQNSDLTRPLQKRMQTHV", "length": 787, "header": "tr|A0A8M9P1K3-1|A0A8M9PG27_DANRE Computationally mapped isoform of Kin of IRRE-like protein 3 isoform X1 OS=Danio rerio OX=7955 GN=kirrel3b PE=3 SV=1 CANONICAL=A0A8M9PG27-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PAN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27/entry#A0A8M9PAN4-1", "sequence": { "sequence": "MPERSPPRRVKMILEVFLILWLTGHGVNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQAIQAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVEPQPVLEGNLVKFHCSAKANPPVTQYKWAKGGSVIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQGGSQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRNAHLVMPTLPTSICAQQRELASKIKTENLKGVVSAKNDIRVEIVHKDHNAARESEEHSGMKQLMIERGEFQQESVLKQLEVLQEEEKEYQHIKDPTNGYYSVNTFKEHHGTPTTMAGNQTTELRRDPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSKASASSSSHYSQSSSQNSDLTRPLQKRMQTHV", "length": 786, "header": "tr|A0A8M9PAN4-1|A0A8M9PAN4_DANRE Computationally mapped isoform of Kin of IRRE-like protein 3 isoform X6 OS=Danio rerio OX=7955 GN=kirrel3b PE=3 SV=1 CANONICAL=A0A8M9PG27-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PG27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27/entry#A0A8M9PG27-1", "sequence": { "sequence": "MPERSPPRRVKMILEVFLILWLTGHGVNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQAIQAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVEPQPVLEGNLVKFHCSAKANPPVTQYKWAKGGSVIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQGGSQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRKKSAHLCTEDAHLVMPTLPTSICAQQRELASKIKTENLKGVVSAKNDIRVEIVHKDHNAARESEEHSGMKQLMIERGEFQQESVLKQLEVLQEEEKEYQHIKDPTNGYYSVNTFKEHHGTPTTMAGNQTTELRRDPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSKASASSSSHYSQSSSQNSDLTRPLQKRMQTHV", "length": 795, "header": "tr|A0A8M9PG27-1|A0A8M9PG27_DANRE Isoform 1 of Kin of IRRE-like protein 3 isoform X1 OS=Danio rerio OX=7955 GN=kirrel3b PE=3 SV=1 CANONICAL=A0A8M9PG27-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PG29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27/entry#A0A8M9PG29-1", "sequence": { "sequence": "MPERSPPRRVKMILEVFLILWLTGHGVNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQAIQAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVEPQPVLEGNLVKFHCSAKANPPVTQYKWAKGGSVIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQGGSQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRNLKGVVSAKNDIRVEIVHKDHNAARESEEHSGMKQLMIERGEFQQESVLKQLEVLQEEEKEYQHIKDPTNGYYSVNTFKEHHGTPTTMAGNQTTELRRDPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSKASASSSSHYSQSSSQNSDLTRPLQKRMQTHV", "length": 759, "header": "tr|A0A8M9PG29-1|A0A8M9PG29_DANRE Computationally mapped isoform of Kin of IRRE-like protein 3 isoform X9 OS=Danio rerio OX=7955 GN=kirrel3b PE=3 SV=1 CANONICAL=A0A8M9PG27-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PMU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27/entry#A0A8M9PMU4-1", "sequence": { "sequence": "MPERSPPRRVKMILEVFLILWLTGHGVNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQAIQAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVEPQPVLEGNLVKFHCSAKANPPVTQYKWAKGGSVIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRKKSAHLCTEDAHLVMPTLPTSICAQQRELASKIKTENLKGVVSAKNDIRVEIVHKDHNAARESEEHSGMKQLMIERGEFQQESVLKQLEVLQEEEKEYQHIKDPTNGYYSVNTFKEHHGTPTTMAGNQTTELRRDPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSKASASSSSHYSQSSSQNSDLTRPLQKRMQTHV", "length": 791, "header": "tr|A0A8M9PMU4-1|A0A8M9PMU4_DANRE Computationally mapped isoform of Kin of IRRE-like protein 3 isoform X3 OS=Danio rerio OX=7955 GN=kirrel3b PE=3 SV=1 CANONICAL=A0A8M9PG27-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PR41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27/entry#A0A8M9PR41-1", "sequence": { "sequence": "MPERSPPRRVKMILEVFLILWLTGHGVNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQAIQAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVEPQPVLEGNLVKFHCSAKANPPVTQYKWAKGGSVIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQGGSQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRKKSAHLCTDAHLVMPTLPTSICAQQRELASKIKTENLKGVVSAKNDIRVEIVHKDHNAARESEEHSGMKQLMIERGEFQQESVLKQLEVLQEEEKEYQHIKDPTNGYYSVNTFKEHHGTPTTMAGNQTTELRRDPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSKASASSSSHYSQSSSQNSDLTRPLQKRMQTHV", "length": 794, "header": "tr|A0A8M9PR41-1|A0A8M9PR41_DANRE Computationally mapped isoform of Kin of IRRE-like protein 3 isoform X2 OS=Danio rerio OX=7955 GN=kirrel3b PE=3 SV=1 CANONICAL=A0A8M9PG27-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PR44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27/entry#A0A8M9PR44-1", "sequence": { "sequence": "MPERSPPRRVKMILEVFLILWLTGHGVNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQAIQAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVEPQPVLEGNLVKFHCSAKANPPVTQYKWAKGGSVIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRNLKGVVSAKNDIRVEIVHKDHNAARESEEHSGMKQLMIERGEFQQESVLKQLEVLQEEEKEYQHIKDPTNGYYSVNTFKEHHGTPTTMAGNQTTELRRDPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSKASASSSSHYSQSSSQNSDLTRPLQKRMQTHV", "length": 755, "header": "tr|A0A8M9PR44-1|A0A8M9PR44_DANRE Computationally mapped isoform of Kin of IRRE-like protein 3 isoform X10 OS=Danio rerio OX=7955 GN=kirrel3b PE=3 SV=1 CANONICAL=A0A8M9PG27-1" }, "locus": {} }, { "isoform_ac": "A0AC58HV06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27/entry#A0AC58HV06-1", "sequence": { "sequence": "MPERSPPRRVKMILEVFLILWLTGHGVNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQAIQAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVEPQPVLEGNLVKFHCSAKANPPVTQYKWAKGGSVIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRNAHLVMPTLPTSICAQQRELASKIKTENLKGVVSAKNDIRVEIVHKDHNAARESEEHSGMKQLMIERGEFQQESVLKQLEVLQEEEKEYQHIKDPTNGYYSVNTFKEHHGTPTTMAGNQTTELRRDPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSKASASSSSHYSQSSSQNSDLTRPLQKRMQTHV", "length": 782, "header": "tr|A0AC58HV06-1|A0AC58HV06_DANRE Computationally mapped isoform of Kin of IRRE-like protein 3 isoform X8 OS=Danio rerio OX=7955 GN=kirrel3b PE=3 SV=1 CANONICAL=A0A8M9PG27-1" }, "locus": {} }, { "isoform_ac": "A0AC58HV23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27/entry#A0AC58HV23-1", "sequence": { "sequence": "MPERSPPRRVKMILEVFLILWLTGHGVNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQAIQAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVEPQPVLEGNLVKFHCSAKANPPVTQYKWAKGGSVIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRKDAHLVMPTLPTSICAQQRELASKIKTENLKGVVSAKNDIRVEIVHKDHNAARESEEHSGMKQLMIERGEFQQESVLKQLEVLQEEEKEYQHIKDPTNGYYSVNTFKEHHGTPTTMAGNQTTELRRDPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSKASASSSSHYSQSSSQNSDLTRPLQKRMQTHV", "length": 783, "header": "tr|A0AC58HV23-1|A0AC58HV23_DANRE Computationally mapped isoform of Kin of IRRE-like protein 3 isoform X7 OS=Danio rerio OX=7955 GN=kirrel3b PE=3 SV=1 CANONICAL=A0A8M9PG27-1" }, "locus": {} }, { "isoform_ac": "A0AC58HV51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27/entry#A0AC58HV51-1", "sequence": { "sequence": "MPERSPPRRVKMILEVFLILWLTGHGVNAVFSQQPQDLVVVAGQPVTLPCSIPGYHGVVLWLRDGLALGVGRDLSGYPRYAVVGDHGSGEHHLRIQKVELMDDAVFECQAIQAAMRSRPARLTVLVPPDDPMITGGPVVSLRAGDPLNLTCHADNAKPAASIIWIRNGEVLNGAMYSKTLLRDGRRESTVSTLYISASNIESGQKIICRASNKAVPNGKETSVTIDIQHLPLVNLSVEPQPVLEGNLVKFHCSAKANPPVTQYKWAKGGSVIKEVSGDTYEVIVDHSFFTEPVSCEVTNPLGSTNISRNVDVYFGPRMAAEPQSLQVDLGSDAVFNCAWTGNPSLTIVWMKRGSGVVLSNENILTLKSVRQEDAGKYVCRAVVPRVGAAEKEVSLTVNGPPTISSTQTHQAPHGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGRYTVETVSTEDGVLSTLTMSNIVPADFQTIYNCTAWNSFGSDTEIIRLKEQDSLPVAVIIGVAVGAFVAFIVLMGTIGAFCCTRSQRKKSAHLCTDAHLVMPTLPTSICAQQRELASKIKTENLKGVVSAKNDIRVEIVHKDHNAARESEEHSGMKQLMIERGEFQQESVLKQLEVLQEEEKEYQHIKDPTNGYYSVNTFKEHHGTPTTMAGNQTTELRRDPATATTGKQRVPTGMSFTNIYSTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSMSDSSSFLDTQCDSSVSSYSKQDGYVQFDKDSKASASSSSHYSQSSSQNSDLTRPLQKRMQTHV", "length": 790, "header": "tr|A0AC58HV51-1|A0AC58HV51_DANRE Computationally mapped isoform of Kin of IRRE-like protein 3 isoform X4 OS=Danio rerio OX=7955 GN=kirrel3b PE=3 SV=1 CANONICAL=A0A8M9PG27-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:572369", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:572369", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZQV3-1", "protein_name": "Kirre like nephrin family adhesion molecule 3", "gene_name": "Kirrel3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPFQLDLLFLCFFLFSQELGLQRRGCCLVLGYMAKDKFRRMNEGQVYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPIILGGPVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNIVTFHCSAKANPAVTQYRWAKRGHIIKEASGELYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTSEPQSLLVDLGSDAVFSCAWIGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETVNTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQRSTGGRPGISGRGTEQKARLRLPRRANLKGVVSAKNDIRVEIVHKEPASGREAEDHTTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTPTISLSSCQPDLRPTGKQRVPTGMSFTNIYSTLSGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSSHHSQSSSQNSDPSRPLQRRMQTHV", "length": 803 }, "evidence": [ { "id": "HGNC:23204", "url": "https://alliancegenome.org/gene/HGNC:23204#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100713-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100713-3#orthology", "database": "AGR" }, { "id": "MGI:1914953", "url": "https://alliancegenome.org/gene/MGI:1914953#orthology", "database": "AGR" }, { "id": "RGD:1311382", "url": "https://alliancegenome.org/gene/RGD:1311382#orthology", "database": "AGR" }, { "id": "FB:FBgn0003285", "url": "https://alliancegenome.org/gene/FB:FBgn0003285#orthology", "database": "AGR" }, { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M6Z878-1", "protein_name": "Kin of IRRE-like protein 1", "gene_name": "kirrel1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGFSMTCLWIVTLAIISVHRVFSGPRFSQEPADQSVVIGERVVLSCVVFNYTGIVQWTKDGLALGIGEDLRAWPRYRVLRIMDVGQYNLEITSADLTDDSLYECQATEAALRSRRAKLTVLIPPDGPVIEGSPEILLTAGTSFNLTCVSRGAKPMSTIEWYKDGIIVEGAHTSTEVLSDRKRVTTKSFLEIQPMDTDTGRNFTCVASNLAAPLGKRSTVTLNIHHPPTVILSIEPRSVLEGERVKFTCQATANPPIMGYRWAKGGVILDGARESVFETTADHSFFTEPVSCLVFNAVGSTNVSILVDVHFGPILVVEPRPVTVDVDSDVTLNCKWSGNPPLTLTWTKKGSSMVLSNSNQLFLKSVSQADAGQYVCKAIVPRIGVGETEVTLTVNGPPIISSEPIQYAVRGEKGEIKCYIASTPPPDKIVWAWKENVWEKERGTLLERYTVEQSRPATQGGAVLSTLTINNVMEADFQSTYNCTAWNAFGPGTMIITLEETDIASEDIVPVGVIAGGSVGSSILLLLLLFALIFYLYRQRKSSRRGVTLKPDIKVETVNKETNLEEEAASASTATRMVKAMYSFLPSVSLSPSTQPFKDDMDLKQDLQTETLEPKVEEYEAKDPTNGYYNVRATTHDEVRSSTRSLLYQEFRAPNPASVSASTGGPANIHPAPTGRYEARPTSRMAHNTYAHFNTIARASQIQPPANPVSKTTDYPAERGLLESTNPLAFDSYAYSTTPQYRLGFAPPLEAGPAYEMYPTGQGVGTSQDANVGKYPSSAQFPYSTPPTEYSQRHTQRMQTHV", "length": 801 }, "evidence": [ { "id": "FB:FBgn0003285", "url": "https://alliancegenome.org/gene/FB:FBgn0003285#orthology", "database": "AGR" }, { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A6Z9-1", "protein_name": "Kin of IRRE-like protein 1", "gene_name": "kirrel1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQGLLLLLSLALSFHRVRTARFSQEPADQSVVLGQRVVLSCVVFNYSGIVQWTKDGLALGIGEDLRAWPRYRVLRLVDVGQYNLEISAAELSDDSLYECQATEAALRSRRAKLTVLIPPDEPVIEGSPEILLTAGVPYNMSCVSRGAKPASVIEWQKDGLPIEGAVSTTEVLPDRKRVTTRSYLPIQPLDTDTGKNFTCVATNLAVPMGKRATITLNVHHPPVVTLSIEPRSVLEGERVTFTCQATANPPIMGYKWAKGGVVIQGARESVFVTKADHSFFTEPVSCQVFNAVGSTNVSILVDVHFGPILVVEPKPVTVDVDSDVTLNCKWAGNPPLTLTWTKKGSSMVLSNNNQLYLKSVSQADAGQYVCKAIVPRIGVGETEVTLTVNGPPIISSEPFQYAVRGERGEVKCYIASTPPPDKIVWAWKENVWEKEKGTLSERYTVEQSKPSAQGGAVLSTLTINNIMESDFQSTYNCTAWNSFGSGTMIISLEEMEIVPVGIIAGGTVGCSILLLLCLLALVLFLYRQRKGSRRGVTLGKPDIKVETINKESHSLEEDSGSVSTATRMVKAMYSFLPSVTLSPSSQPFKDDIDLKQELRSDTLDTRQDYELKDPTNGYYNVRASTHDEGRPASRSMHYSDYRTSSQPGGAAAVVSSSSGPPPGATAGPGTPSSLAPGSRAGCYDPRPPSRLSHNSYAQFNTFTRAGQSQQPPPGSGPQTSDFPAECSLLDSSGQLGYENYGYPSHYPTFRMGFAPPSLAPLEGGPAYEMYGVGPSVGAGGGAGTPETGLGKYGSSTRFSYTSQHSDYSHRHTQRMQTHV", "length": 819 }, "evidence": [ { "id": "FB:FBgn0003285", "url": "https://alliancegenome.org/gene/FB:FBgn0003285#orthology", "database": "AGR" }, { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32U2T1-1", "protein_name": "Kin of IRRE-like protein 3 isoform X1", "gene_name": "kirrel3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLIISKRVSSLTQILTFPKWRTCGTANLEPGGCVMFIQQPHDLVIVAGEPVTLPCTIIGYQGMVLWVKDGLALGVNRDLSGYPRYDVIGDHSKGEYHLLIERTELVDDGSFECQAIQVAGRSRPAQLTVLVPPDDPVIIGAPVVSLRAGDSLNLTCHANNAKPAASIIWIRNGEVINGAAYTKTLLRDGKRESTVSTLHISASNIESGQQITCRASNKAAPNGKEATVTIDIQHFPLVNLSVEPQPVLEGNLVKFHCAAKANPPVTHYRWAKGGSMITDATGDTYEVLVDHSFFTEPVSCEVTNALGSTNISRNVDVYFGPRLAAEPQSLQVDRGSDAVFSCAWIGNPSLTIVWMKRGHGVVLSNENTLTLKAVRQEDAGKYVCRAVVPRVGVGEKEVMLTVNGPPSISSTQTQQALYGEKGQIKCFIRSTPPPDRIAWSWKETVLESGTSGRYTVETVSTEEGVISTLTMRNIVPTDFQTIYNCTAWNSFGSDTEIIRLKEQGSLRLAVIIGVAVGAFLALIVLIGTLGAFCCARLQRKDMHLVMSSLPVSLSSRQREISGTVKSENLKGVVSAKNDIRVEIVHKDHNAAREPEEHSNVKQMMMERADFQQESVLKQLEVLQEEERELQHIKDPTNGYYSVNTFKEQPTPTISLTANQNAEVRNPATATLGKHRVPTGMSYTNIYNTLGAGPNRLYDYSQRFVLGMGSSSIELCEREFQRGSLSDSSSFQDTQCDSSVSSYSKQDGYVQFDKASKASVSSSSHYSQSSSQNSDLTRPLQKRMQTHV", "length": 788 }, "evidence": [ { "id": "HGNC:23204", "url": "https://alliancegenome.org/gene/HGNC:23204#orthology", "database": "AGR" }, { "id": "MGI:1914953", "url": "https://alliancegenome.org/gene/MGI:1914953#orthology", "database": "AGR" }, { "id": "RGD:1311382", "url": "https://alliancegenome.org/gene/RGD:1311382#orthology", "database": "AGR" }, { "id": "FB:FBgn0003285", "url": "https://alliancegenome.org/gene/FB:FBgn0003285#orthology", "database": "AGR" }, { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A934-1", "protein_name": "Kin of IRRE-like protein 2", "gene_name": "Kirrel2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLASALLVVLCCFRGNAGSSPHFLQQPEDMVVLLGQEARLPCALGAYRGLVQWTKDGLALGGERDLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQASQAGLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGVPGNLTCRSRGDARPAPELLWFRDGIRLDGTSFHQITLRDKATGTVENTLFLTPSSQDDGATLICRARSQALPTGRDTAVTLSLQYPPMVTLSAEPQTAQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADATFLTEPVSCEVSNAVGSANRSTALEVLYGPILQAKPKPVSVDVGKDASFSCVWRGNPLPRISWTRLGGSQVLSSGPTLRLPSVALEDAGDYVCRAEPRRTGVGGGTAQARLTVNAPPVVTALHPAPAFLRGPARLQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPEVEGGQGPGLISVLHISGTQESDFTTGFNCSARNRLGEGRVQIHLGRRDLLPTVRLVAGAASAATSLFMVITGVVLCCWRHGSLSKQKNLVRIPGSSEGSSAHGPEEETGSSEDRGPIVHTDHNDLVLEENEALETKDPTNGYYKVRGVSVSLSLGEAPGGGLFLPPPSPMGLPGTPTYYDFKPHLDLVPPCRLYRARAGYLTTPHPRAFTNYMKPTSFGPPDLSSGTPPFPYATLSPPSHQRLQTHV", "length": 700 }, "evidence": [ { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08180-1", "protein_name": "Irregular chiasm C-roughest protein", "gene_name": "rst", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLHTMQLLLLATIVGMVRSSPYTSYQNQRFAMEPQDQTAVVGARVTLPCRVINKQGTLQWTKDDFGLGTSRDLSGFERYAMVGSDEEGDYSLDIYPVMLDDDARYQCQVSPGPEGQPAIRSTFAGLTVLVPPEAPKITQGDVIYATEDRKVEIECVSVGGKPAAEITWIDGLGNVLTDNIEYTVIPLPDQRRFTAKSVLRLTPKKEHHNTNFSCQAQNTADRTYRSAKIRVEVKYAPKVKVNVMGSLPGGAGGSVGGAGGGSVHMSTGSRIVEHSQVRLECRADANPSDVRYRWFINDEPIIGGQKTEMVIRNVTRKFHDAIVKCEVQNSVGKSEDSETLDISYAPSFRQRPQSMEADVGSVVSLTCEVDSNPQPEIVWIQHPSDRVVGTSTNLTFSVSNETAGRYYCKANVPGYAEISADAYVYLKGSPAIGSQRTQYGLVGDTARIECFASSVPRARHVSWTFNGQEISSESGHDYSILVDAVPGGVKSTLIIRDSQAYHYGKYNCTVVNDYGNDVAEIQLQAKKSVSLLMTIVGGISVVAFLLVLTILVVVYIKCKKRTKLPPADVISEHQITKNGGVSCKLEPGDRTSNYSDLKVDISGGYVPYGDYSTHYSPPPQYLTTCSTKSNGSSTIMQNNHQNQLQLQQQQQQSHHQHHTQTTTLPMTFLTNSSGGSLTGSIIGSREIRQDNGLPSLQSTTASVVSSSPNGSCSNQSTTAATTTTTHVVVPSSMALSVDPRYSAIYGNPYLRSSNSSLLPPPTAV", "length": 764 }, "evidence": [ { "id": "HGNC:23204", "url": "https://alliancegenome.org/gene/HGNC:23204#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100713-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100713-3#orthology", "database": "AGR" }, { "id": "MGI:1914953", "url": "https://alliancegenome.org/gene/MGI:1914953#orthology", "database": "AGR" }, { "id": "RGD:1311382", "url": "https://alliancegenome.org/gene/RGD:1311382#orthology", "database": "AGR" }, { "id": "FB:FBgn0003285", "url": "https://alliancegenome.org/gene/FB:FBgn0003285#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q6UWL6-1", "protein_name": "Kin of IRRE-like protein 2", "gene_name": "KIRREL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRMRVPALLVLLFCFRGRAGPSPHFLQQPEDLVVLLGEEARLPCALGAYWGLVQWTKSGLALGGQRDLPGWSRYWISGNAANGQHDLHIRPVELEDEASYECQATQAGLRSRPAQLHVLVPPEAPQVLGGPSVSLVAGVPANLTCRSRGDARPTPELLWFRDGVLLDGATFHQTLLKEGTPGSVESTLTLTPFSHDDGATFVCRARSQALPTGRDTAITLSLQYPPEVTLSASPHTVQEGEKVIFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADASFLTEPVSCEVSNAVGSANRSTALDVLFGPILQAKPEPVSVDVGEDASFSCAWRGNPLPRVTWTRRGGAQVLGSGATLRLPSVGPEDAGDYVCRAEAGLSGLRGGAAEARLTVNAPPVVTALHSAPAFLRGPARLQCLVFASPAPDAVVWSWDEGFLEAGSQGRFLVETFPAPESRGGLGPGLISVLHISGTQESDFSRSFNCSARNRLGEGGAQASLGRRDLLPTVRIVAGVAAATTTLLMVITGVALCCWRHSKASASFSEQKNLMRIPGSSDGSSSRGPEEEETGSREDRGPIVHTDHSDLVLEEEGTLETKDPTNGYYKVRGVSVSLSLGEAPGGGLFLPPPSPLGPPGTPTFYDFNPHLGMVPPCRLYRARAGYLTTPHPRAFTSYIKPTSFGPPDLAPGTPPFPYAAFPTPSHPRLQTHV", "length": 708 }, "evidence": [ { "id": "FB:FBgn0003285", "url": "https://alliancegenome.org/gene/FB:FBgn0003285#orthology", "database": "AGR" }, { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6X936-1", "protein_name": "Kin of IRRE-like protein 1", "gene_name": "Kirrel1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLENRSTCLMTCQSSLLPKKPRFLSQKMWAPHLVVAYLIFVTLALALPGTQTRFSQEPADQTVVAGHRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIQPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQTVLEGERVIFTCQATANPEILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPVGIIAGATIGAGILLVFSFAALVFFLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDTTSISTATRVMKAIYSSFKDDVDLKQDLHCDTIETREEYEMKDPTNGYYNVRAHEDRPSSRAVLYADYRAPGPTRFDGRPSSRLSHSSGYAQLNTYSRAPASDYGTEPTPSGPSAPGGTDTTSQLSYENYEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTPYEAYDPIGKYATATRFSYTSQHSDYGQRFQQRMQTHV", "length": 789 }, "evidence": [ { "id": "FB:FBgn0003285", "url": "https://alliancegenome.org/gene/FB:FBgn0003285#orthology", "database": "AGR" }, { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TSU7-1", "protein_name": "Kin of IRRE-like protein 2", "gene_name": "Kirrel2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLASALLVFLCCFKGHAGSSPHFLQQPEDMVVLLGEEARLPCALGAYRGLVQWTKDGLALGGERDLPGWSRYWISGNSASGQHDLHIKPVELEDEASYECQASQAGLRSRPAQLHVMVPPEAPQVLGGPSVSLVAGVPGNLTCRSRGDSRPAPELLWFRDGIRLDGSSFHQTTLKDKATGTVENTLFLTPSSHDDGATLICRARSQALPTGRDTAVTLSLQYPPMVTLSAEPQTVQEGEKVTFLCQATAQPPVTGYRWAKGGSPVLGARGPRLEVVADATFLTEPVSCEVSNAVGSANRSTALEVLYGPILQAKPKSVSVDVGKDASFSCVWRGNPLPRITWTRMGGSQVLSSGPTLRLPSVALEDAGDYVCRAEPRRTGLGGGKAQARLTVNAPPVVTALQPAPAFLRGPARLQCVVFASPAPDSVVWSWDEGFLEAGSLGRFLVEAFPAPEVEGGQGPGLISVLHISGTQESDFTTGFNCSARNRLGEGRVQIHLGRRDLLPTVRIVAGAASAATSLLMVITGVVLCCWRHGSLSKQKNLVRIPGSSEGSSSRGPEEETGSSEDRGPIVHTDHSDLVLEEKEALETKDPTNGYYRVRGVSVSLSLGEAPGGGLFLPPPSPIGLPGTPTYYDFKPHLDLVPPCRLYRARAGYLTTPHPRAFTSYMKPTSFGPPELSSGTPPFPYATLSPPSHQRLQTHV", "length": 700 }, "evidence": [ { "id": "FB:FBgn0003285", "url": "https://alliancegenome.org/gene/FB:FBgn0003285#orthology", "database": "AGR" }, { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80W68-1", "protein_name": "Kin of IRRE-like protein 1", "gene_name": "Kirrel1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLESPSTRLMTCQSSLLPEKPRFLSQKMWAPHLVVAYLIFVTLALALPGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEETRIDGGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQTVLEGERVIFTCQATANPEILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQFAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPVGIIAGATIGAGILVVFSFAALVFFLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDTASISTATRVMKAIYSSFKDDVDLKQDLRCDTIDTREEYEMKDPTNGYYNVRAHEDRPSSRAVLYADYRAPGPTRFDGRPSSRLSHSSGYAQLNTYSRAPASDYGTEPTPSGPSAPGGTDTTSQLSYENYEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTPYEAYDPIGKYATATRFSYTSQHSDYGQRFQQRMQTHV", "length": 789 }, "evidence": [ { "id": "FB:FBgn0003285", "url": "https://alliancegenome.org/gene/FB:FBgn0003285#orthology", "database": "AGR" }, { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BR86-1", "protein_name": "Kin of IRRE-like protein 3", "gene_name": "Kirrel3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPFQLDLLFLCFFLFSQELGLQKRGCCLVLGYMAKDKFRRMNEGQVYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPIILGGPVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNIVTFHCSAKANPAVTQYRWAKRGHIIKEASGELYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTSEPQSLLVDLGSDAVFSCAWIGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETVNTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQRNLKGVVSAKNDIRVEIVHKEPSSGREAEDHTTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTPTISLSSCQPDLRPTGKQRVPTGMSFTNIYSTLSGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSSHHSQSSSQNSDPSRPLQRRMQTHV", "length": 778 }, "evidence": [ { "id": "HGNC:23204", "url": "https://alliancegenome.org/gene/HGNC:23204#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100713-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100713-3#orthology", "database": "AGR" }, { "id": "MGI:1914953", "url": "https://alliancegenome.org/gene/MGI:1914953#orthology", "database": "AGR" }, { "id": "RGD:1311382", "url": "https://alliancegenome.org/gene/RGD:1311382#orthology", "database": "AGR" }, { "id": "FB:FBgn0003285", "url": "https://alliancegenome.org/gene/FB:FBgn0003285#orthology", "database": "AGR" }, { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZU9-1", "protein_name": "Kin of IRRE-like protein 3", "gene_name": "KIRREL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPFQLDLLFVCFFLFSQELGLQKRGCCLVLGYMAKDKFRRMNEGQVYSFSQQPQDQVVVSGQPVTLLCAIPEYDGFVLWIKDGLALGVGRDLSSYPQYLVVGNHLSGEHHLKILRAELQDDAVYECQAIQAAIRSRPARLTVLVPPDDPVILGGPVISLRAGDPLNLTCHADNAKPAASIIWLRKGEVINGATYSKTLLRDGKRESIVSTLFISPGDVENGQSIVCRATNKAIPGGKETSVTIDIQHPPLVNLSVEPQPVLEDNVVTFHCSAKANPAVTQYRWAKRGQIIKEASGEVYRTTVDYTYFSEPVSCEVTNALGSTNLSRTVDVYFGPRMTTEPQSLLVDLGSDAIFSCAWTGNPSLTIVWMKRGSGVVLSNEKTLTLKSVRQEDAGKYVCRAVVPRVGAGEREVTLTVNGPPIISSTQTQHALHGEKGQIKCFIRSTPPPDRIAWSWKENVLESGTSGRYTVETISTEEGVISTLTISNIVRADFQTIYNCTAWNSFGSDTEIIRLKEQGSEMKSGAGLEAESVPMAVIIGVAVGAGVAFLVLMATIVAFCCARSQRNLKGVVSAKNDIRVEIVHKEPASGREGEEHSTIKQLMMDRGEFQQDSVLKQLEVLKEEEKEFQNLKDPTNGYYSVNTFKEHHSTPTISLSSCQPDLRPAGKQRVPTGMSFTNIYSTLSGQGRLYDYGQRFVLGMGSSSIELCEREFQRGSLSDSSSFLDTQCDSSVSSSGKQDGYVQFDKASKASASSSHHSQSSSQNSDPSRPLQRRMQTHV", "length": 778 }, "evidence": [ { "id": "HGNC:23204", "url": "https://alliancegenome.org/gene/HGNC:23204#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100713-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100713-3#orthology", "database": "AGR" }, { "id": "MGI:1914953", "url": "https://alliancegenome.org/gene/MGI:1914953#orthology", "database": "AGR" }, { "id": "RGD:1311382", "url": "https://alliancegenome.org/gene/RGD:1311382#orthology", "database": "AGR" }, { "id": "FB:FBgn0003285", "url": "https://alliancegenome.org/gene/FB:FBgn0003285#orthology", "database": "AGR" }, { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96J84-1", "protein_name": "Kin of IRRE-like protein 1", "gene_name": "KIRREL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSLLVWILTLSDTFSQGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPVILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIGRVFTCRSMNEAIPSGKETSIELDVHHPPTVTLSIEPQTVQEGERVVFTCQATANPEILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPVSCEVHNKVGSTNVSTLVNVHFAPRIVVDPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQYAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEVGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREVLPVGIIAGATIGASILLIFFFIALVFFLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDTASVSTATRVMKAIYSSFKDDVDLKQDLRCDTIDTREEYEMKDPTNGYYNVRAHEDRPSSRAVLYADYRAPGPARFDGRPSSRLSHSSGYAQLNTYSRGPASDYGPEPTPPGPAAPAGTDTTSQLSYENYEKFNSHPFPGAAGYPTYRLGYPQAPPSGLERTPYEAYDPIGKYATATRFSYTSQHSDYGQRFQQRMQTHV", "length": 757 }, "evidence": [ { "id": "FB:FBgn0003285", "url": "https://alliancegenome.org/gene/FB:FBgn0003285#orthology", "database": "AGR" }, { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W4T9-1", "protein_name": "Kin of irre, isoform A", "gene_name": "kirre", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKRMRSSRLLVLPLILVLILTLLLQPIAVHAKSKKNKSSQSSHHGDSSSSSSSSSSSSGSSSAAASSANDESKPKGGDNGGQHFAMEPQDQTAVVGSRVTLPCRVMEKVGALQWTKDDFGLGQHRNLSGFERYSMVGSDEEGDFSLDIYPLMLDDDAKYQCQVGPGPQGEQGIRSRFAKLTVLVPPEAPKITQGDYLVTTEDREIELECVSQGGKPAAEITWIDGLGNVLTKGIEYVKEPLADSRRITARSILKLAPKKEHHNTTFTCQAQNTADRTYRSAKLLLEVKYAPKVIVSVVGGALAGGKIPEGAEVILSCQADANPHELSYRWFINDELMTGDFTTKMIIHNVSRQYHDAIVKCEVVNAVGKSEQSKKLDISFGPVFRQRPVSVEADLGATVSMRCDVAGNPEPEIEWISENSDQVVGVAAELKLKVSSETAGRYFCKAVVNGFPEIGAEATLYVKRAPIITSHKVQFGGVGGRVKIDCLAFSIPKAEHILWSFEGKIINMSSADPDIYIFEEHHLPEGVRAALIIRDSKATHFGKYNCTVMNSYGGDSLVITLLREPGNIPVLLVVMGSMFCVAIILMIVMIIIVYRKRRSRKKPMPADVIPEASRGGDKLNELKSELRSKAYDVEYSEAGGDGLAINLTQSPMPDVQMKGATLGVPLAGPVKFDERFSGDFGGDRYNRQCHIKNLKNQQETAYKGSPQANGYAHYFEYALDYSPPGGEGAAVVVGSGGVGKLKNGGMNSATLPHSAAATVNGGGAGNGGGASLPRNQRHEIQQSQQSNGFLGQPLLQNGIDSRFSAIYGNPYLRTNSSLLPPLPPPSTANPAATPAPPPYHAARHGHAHHANGGLKHFVGGAVITTSPVGNVNINGGGGGGSTPSGGGGVGVGVAAGGSVSGSSSNLTASSNTLAATPLAGGGVGNSGQCAQSPSGQFILSNNGKGHTQKGPLATHV", "length": 956 }, "evidence": [ { "id": "HGNC:23204", "url": "https://alliancegenome.org/gene/HGNC:23204#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100713-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100713-3#orthology", "database": "AGR" }, { "id": "MGI:1914953", "url": "https://alliancegenome.org/gene/MGI:1914953#orthology", "database": "AGR" }, { "id": "RGD:1311382", "url": "https://alliancegenome.org/gene/RGD:1311382#orthology", "database": "AGR" }, { "id": "FB:FBgn0028369", "url": "https://alliancegenome.org/gene/FB:FBgn0028369#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG27", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG27", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cell adhesion molecule binding", "id": "GO:0050839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050839", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG27", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell-cell adhesion", "id": "GO:0098609", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098609", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG27", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27" } ], "pmid": "" }, { "name": "synapse assembly", "id": "GO:0007416", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007416", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG27", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 665, "end_pos": 667, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PG27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG27" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 123, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 479, "end_pos": 481 }, { "start_pos": 665, "end_pos": 667 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P248-1", "uniprot_ac": "A0A8M9P248", "uniprot_id": "A0A8M9P248_DANRE", "mass": { "chemical_mass": 15460.0, "monoisotopic_mass": 15460.0 }, "refseq": { "ac": "XP_021323892", "name": "brain and acute leukemia cytoplasmic protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323892" }, "gene_names": [ { "name": "si:ch211-215i13.3", "type": "recommended", "evidence": [ { "id": "A0A8M9P248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P248" } ] }, { "name": "si:ch211-215i13.3", "type": "synonym", "evidence": [ { "id": "XP_021323892", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323892" } ] } ], "protein_names": [ { "name": "Brain and acute leukemia cytoplasmic protein", "type": "synonym", "evidence": [ { "id": "A0A8M9P248", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P248/entry#names_and_taxonomy" } ] }, { "name": "brain and acute leukemia cytoplasmic protein", "type": "synonym", "evidence": [ { "id": "XP_021323892", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323892" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323892.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323892" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P248", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P248" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-215i13.3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P248", "locus": {} } ], "crossref": [ { "id": "A0A8M9P248", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P248", "database": "AlphaFoldDB", "categories": [] }, { "id": "101884762", "url": "https://www.ncbi.nlm.nih.gov/gene/101884762", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009728", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009728", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101884762", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884762", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P248", "url": "https://www.orthodb.org/?gene=A0A8M9P248", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14731", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14731", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14731:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14731:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323892", "database": "RefSeq", "categories": [ "Protein" ] 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of Brain and acute leukemia cytoplasmic protein OS=Danio rerio OX=7955 GN=si:ch211-215i13.3 PE=4 SV=2 CANONICAL=A0A8M9P248-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101884762", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884762", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P248", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P248" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P2G6-1", "uniprot_ac": "A0A8M9P2G6", "uniprot_id": "A0A8M9P2G6_DANRE", "mass": { "chemical_mass": 30638.0, "monoisotopic_mass": 30638.0 }, "refseq": { "ac": "XP_073788261", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073788261" }, "gene_names": [ { "name": "LOC108179272", "type": "recommended", "evidence": [ { "id": "A0A8M9P2G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2G6" } ] }, { "name": "LOC108179272", "type": "synonym", "evidence": [ { "id": "XP_073788261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073788261" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9P2G6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2G6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_073788261", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073788261" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073788261", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073788261" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2G6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2G6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108179272", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2G6", "locus": {} } ], "crossref": [ { "id": "108179272", "url": "https://www.ncbi.nlm.nih.gov/gene/108179272", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026178", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026178", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108179272", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179272", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VETPWES", "url": "https://omabrowser.org/oma/group/VETPWES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P2G6", "url": "https://www.orthodb.org/?gene=A0A8M9P2G6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22397", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22397", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22397:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22397:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15312", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15312", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073788261", "url": 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"MDESSFETFEDELKKPLPENPPQKPVRQTRAEMYTQRRVREEAPIVQQVPKMIPREHPMSSATSLRRALSIQNLSQMQMERPWEGVTLNRCLIVAITILLLSSGLQRIHDAVRGRKEDSEELTVLTDRHTLLRRGKITPQPDSSLWDTLFWWLDDDDDDEEKSGKHKKVSRSLRHRALPDPRLLKKRKTFTERRGRGEEEIKERQKQMKAKKVEEDENLEKKAKRDSKKKMKAKTNMEEKEEEYMEKKNKAKKSPVKKE", "length": 259, "header": "tr|A0A8M9P2G6-1|A0A8M9P2G6_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108179272 PE=4 SV=2 CANONICAL=A0A8M9P2G6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108179272", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179272", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "skeletal muscle contraction", "id": "GO:0003009", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003009", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2G6", "url": 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[ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P2I5-1", "uniprot_ac": "A0A8M9P2I5", "uniprot_id": "A0A8M9P2I5_DANRE", "mass": { "chemical_mass": 43941.0, "monoisotopic_mass": 43941.0 }, "refseq": { "ac": "XP_073788521", "name": "transmembrane protein 200A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073788521" }, "gene_names": [ { "name": "tmem200cb", "type": "recommended", "evidence": [ { "id": "A0A8M9P2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2I5" } ] }, { "name": "tmem200cb", "type": "synonym", "evidence": [ { "id": "XP_073788521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073788521" } ] } ], "protein_names": [ { "name": "Transmembrane protein 200A", "type": "synonym", "evidence": [ { "id": "A0A8M9P2I5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2I5/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 200A", "type": "synonym", "evidence": [ { "id": "XP_073788521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073788521" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324222" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9P2T4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2T4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021324222", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324222" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324222", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324222" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2T4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2T4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438168", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2T4", "locus": {} } ], "crossref": [ { "id": "A0A8M9P2T4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P2T4", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438168", "url": "https://www.ncbi.nlm.nih.gov/gene/110438168", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:110438168", "url": 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MAVQLRVILEEHNIQKLKLPTGIPNTLEDLVSIITATFQLHGEIGLLYQDSNFDNQFFSVTSTADLHDKATVKVILKEPTITLDLHPVFESSTLSTVSTHPASTAETDICPADHDASSEVSNCESSSSSDTIILPDSCRSAAWPVPFQVPEFSRDIELILAEANNSYHASGRHFMDASIKSAIMQELAKVIFSYTAYPTNEQILSVAEALVSKFPCLREPGSFAGLYGWQQRIKNKMHNYRAKLRSRKYSYPEIEINTLKRKHPADVGPLKNIKKAKKAEVNYLPPHPTGESQETLEKERLELICEITKKNNAKIIADKMNKTFSSRRIEVVSLSPSVDVFKERWPALFTEAQIKEEFRRITMVSLEETFLRKLDEYTPGLLRLMRAKGGAAGCKMRPLLDSLNTQNIEEKRDAVVCCLINYLGERQEDLFHEWQECEEYTDKTMKVIVKHNVMAEEDDLSIVIEGNQVMEGCGSRTKACILLMGLIYAINIEYPKELKNTFEAFQKLFLEIDGAKLLKKVHSLKNKLMK", "length": 530, "header": "tr|A0A8M9P2T4-1|A0A8M9P2T4_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC110438168 PE=4 SV=1 CANONICAL=A0A8M9P2T4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P2T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2T4/entry#A0A8M9P2T4-1", "sequence": { "sequence": 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GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324262" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2V8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "htr1e", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8", "locus": {} } ], "crossref": [ { "id": "A0A8M9P2V8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P2V8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100330681", "url": "https://www.ncbi.nlm.nih.gov/gene/100330681", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100330681", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330681", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P2V8", "url": "https://www.orthodb.org/?gene=A0A8M9P2V8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24248", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24248", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24248:SF191", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24248:SF191", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021324262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324262", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P2V8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P2V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEMERYLGESTSSPANATNTSSEAASQVEALTERLAIVALLSLLTLLTAVVNGAVIAAICTTRKLHLPANYLICSLAVTDFLVSVLVMPISILYITTEEWLLGTYVCEAWLSVDVTCCTCSILHLCVIALDRYWAITKAIEYARKRTARRAGVMVAIVWVISIFISIPPLFWRQRGDANGPQQCIIEHDHVGYTIFSTFGAFYIPMTLILILYSRIYSAAKTLYQKRGSSRHLSSRSTDSQTSFNHCRVKHAFCVSDVSTSDHTMEFERNNVTIVRMPTFDTETPELDERNQICTSRERKAARILGLILGAFILCWLPFFLKELLVGLKVLMTPSPQVSDALTWLGYINSLVNPLLYTSFNEDFKQAFKRLIRRKEHT", "length": 378, "header": "tr|A0A8M9P2V8-1|A0A8M9P2V8_DANRE Isoform 1 of 5-hydroxytryptamine receptor 1E OS=Danio rerio OX=7955 GN=htr1e PE=3 SV=1 CANONICAL=A0A8M9P2V8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P2V8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8/entry#A0A8M9P2V8-1", "sequence": { "sequence": "MEMERYLGESTSSPANATNTSSEAASQVEALTERLAIVALLSLLTLLTAVVNGAVIAAICTTRKLHLPANYLICSLAVTDFLVSVLVMPISILYITTEEWLLGTYVCEAWLSVDVTCCTCSILHLCVIALDRYWAITKAIEYARKRTARRAGVMVAIVWVISIFISIPPLFWRQRGDANGPQQCIIEHDHVGYTIFSTFGAFYIPMTLILILYSRIYSAAKTLYQKRGSSRHLSSRSTDSQTSFNHCRVKHAFCVSDVSTSDHTMEFERNNVTIVRMPTFDTETPELDERNQICTSRERKAARILGLILGAFILCWLPFFLKELLVGLKVLMTPSPQVSDALTWLGYINSLVNPLLYTSFNEDFKQAFKRLIRRKEHT", "length": 378, "header": "tr|A0A8M9P2V8-1|A0A8M9P2V8_DANRE Isoform 1 of 5-hydroxytryptamine receptor 1E OS=Danio rerio OX=7955 GN=htr1e PE=3 SV=1 CANONICAL=A0A8M9P2V8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100330681", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330681", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2V8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2V8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2V8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "G protein-coupled serotonin receptor activity", "id": "GO:0004993", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004993", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2V8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8" } ], "pmid": "" }, { "name": "neurotransmitter receptor activity", "id": "GO:0030594", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030594", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2V8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8" } ], "pmid": "" }, { "name": "alpha2-adrenergic receptor activity", "id": "GO:0004938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004938", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2V8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger", "id": "GO:0007187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007187", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2V8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2V8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8" } ], "pmid": "" }, { "name": "adenylate cyclase-inhibiting adrenergic receptor signaling pathway", "id": "GO:0071881", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071881", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2V8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8" } ], "pmid": "" }, { "name": "adenylate cyclase-inhibiting serotonin receptor signaling pathway", "id": "GO:0007198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007198", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2V8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 19, "end_pos": 21, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P2V8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2V8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 51, "end_pos": 357, "start_aa": "Val", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 19, "end_pos": 21 }, { "start_pos": 271, "end_pos": 273 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P2Z0-1", "uniprot_ac": "A0A8M9P2Z0", "uniprot_id": "A0A8M9P2Z0_DANRE", "mass": { "chemical_mass": 68846.0, "monoisotopic_mass": 68846.0 }, "refseq": { "ac": "XP_021324317", "name": "uncharacterized protein si:dkey-6f10.3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324317" }, "gene_names": [ { "name": "si:dkey-6f10.3", "type": "recommended", "evidence": [ { "id": "A0A8M9P2Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z0" } ] }, { "name": "si:dkey-6f10.3", "type": "synonym", "evidence": [ { "id": "XP_021324317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324317" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkey-6f10.3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P2Z0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkey-6f10.3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021324317", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324317" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021324317.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324317", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324317" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P2Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-6f10.3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z0", "locus": {} } ], "crossref": [ { "id": "A0A8M9P2Z0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P2Z0", "database": "AlphaFoldDB", "categories": [] }, { "id": "795212", "url": "https://www.ncbi.nlm.nih.gov/gene/795212", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:795212", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795212", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_021324317", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324317", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P2Z0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P2Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I5I4", "url": "https://www.uniprot.org/uniprotkb/A0AC58I5I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I5I4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I5I4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVEISCKITKRQKKAQQGKERPGNGTNNEKDKVEKQKKKKKSRVGSFIRAALKWFCFSPRNEPFQLSSSDDYENEVYQKMMVKVEEEKEMIQKEEVVEKVEKVTKEEDEILEKEEEVVIELEEGKEKEKDNTNEGKPEEEGKRKRKKKNISSRLSEEEFWRRRKIEEERVEEKEEEVVIEQKEMEKENINEEKPKDEENMEEEKVKKKRRRRRRPRNCSVEEEAVKENKSEEVEKNEEKEMNDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEAAKENESEEVEKNAEEKEMKDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEAVKENESEEVEKNAEEKEMKDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEAVKENESEEVEKNAEEKEMNDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEAAKENESEEVEKNAEEKEMKDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEAVKENESEEVEKNAEEKEMKDIEIEENMEEMKEKKKRRRRRRPRNCSVEEEAVKENESEEMEKNGRRWPKLHEERERQSYVHVQ", "length": 562, "header": "tr|A0A8M9P2Z0-1|A0A8M9P2Z0_DANRE Isoform 1 of Uncharacterized protein si:dkey-6f10.3 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-6f10.3 PE=4 SV=2 CANONICAL=A0A8M9P2Z0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P2Z0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z0/entry#A0A8M9P2Z0-1", "sequence": { "sequence": "MEVEISCKITKRQKKAQQGKERPGNGTNNEKDKVEKQKKKKKSRVGSFIRAALKWFCFSPRNEPFQLSSSDDYENEVYQKMMVKVEEEKEMIQKEEVVEKVEKVTKEEDEILEKEEEVVIELEEGKEKEKDNTNEGKPEEEGKRKRKKKNISSRLSEEEFWRRRKIEEERVEEKEEEVVIEQKEMEKENINEEKPKDEENMEEEKVKKKRRRRRRPRNCSVEEEAVKENKSEEVEKNEEKEMNDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEAAKENESEEVEKNAEEKEMKDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEAVKENESEEVEKNAEEKEMKDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEAVKENESEEVEKNAEEKEMNDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEAAKENESEEVEKNAEEKEMKDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEAVKENESEEVEKNAEEKEMKDIEIEENMEEMKEKKKRRRRRRPRNCSVEEEAVKENESEEMEKNGRRWPKLHEERERQSYVHVQ", "length": 562, "header": "tr|A0A8M9P2Z0-1|A0A8M9P2Z0_DANRE Isoform 1 of Uncharacterized protein si:dkey-6f10.3 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-6f10.3 PE=4 SV=2 CANONICAL=A0A8M9P2Z0-1" }, "locus": {} }, { "isoform_ac": "A0AC58I5I4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Z0/entry#A0AC58I5I4-1", "sequence": { "sequence": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073791200", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073791200" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P3N8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3N8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-11o18.5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3N8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-110", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-110", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P3N8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P3N8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00112", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00112", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd06263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "797166", "url": "https://www.ncbi.nlm.nih.gov/gene/797166", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023415", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023415", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036055", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036055", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:797166", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797166", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P3N8", "url": "https://www.orthodb.org/?gene=A0A8M9P3N8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23282:SF145", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23282:SF145", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23282:SF150", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23282:SF150", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00057", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00057", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00629", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00629", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073791200", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073791200", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P3N8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P3N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3N8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PD58", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PD58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IAD7", "url": "https://www.uniprot.org/uniprotkb/A0AC58IAD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IAD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-110", "url": "https://zfin.org/ZDB-GENE-091204-110", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKTGFMAACFWILVCVLLNVCQRAAVALDGKDCSSSPENRCDFICDCKDCSDEQDCGYLGPKFVCDFEHEGKCGWTAKPAEGAYMWQRQRRGKTLPDSGPSSDYTTGTSTGWFMAVTAVTSDAPQTAILESPTIKHSSPTCRLRLRYFIWDSGHTGMGETPLWGSVRQTDGEQAVVWRPESSSFRGWREDVIYLGRITGPFNMQLHSRRSEGKQGDVAIDHMEFLDCALPVPSESGKCTGGFVQCKRDGCVEEYKVCDGTDDCGDGTDEENCEQNNSCNFEDGLCWWDLRSMASLKWTWTDQMNISLSEPLKGPGRDHSSNTASGRFLYVTKPNFTASDWTTFQSPPLAPTNETHPCRMVMYTHQFGRVSGGLSVLVAERQFYPVWRRGGALGDLWVKAEVEFVVNSTFQILFVAAIRDQPYGGIAVDDIVLSPGCILSNESMPQAGYPKPPDHPCTKDSSKICDFHEDCTNGEDEDQCGDFSYAKGSSGWTDTSIGSQAWDLKVVNTISKEEFLFVTAAPGQQLSEAQTRTPLLGPSGPVCTLQFSYSLTGTNPHIGELAVYVVDSVMGTQPVLWDFAGRTNETTGTWRKEEVYVGARDHRFQLEFRARAKDLSSSALIAVKDVHFVDCSPMFIPSGDISCNFEVNMCGWYQDQTDNYNWKLHSGMDHTVQDGRSLVVDMWDPSLRGLSGRLLSIRQTSKTEHCLSFFYKLYGPNTGALSVKLLFADGSEELLWMRSGAHGNVWHEGHCPVPPQLSAFQLVFEATRSGFDGQLALDDVAFVEGQCSLPTMCSFESQTCGYTSSGRARWVHQNWASSKNGPTTDHSLETENGFYMLAHSSVDILPEGSVTTLTSPVRKGLSHTECVHFWYHTGGDKPGTLSVYVKPSNGDRILLFSSSVTQGQAWRHAQGNVENHGDWQLQFEVKGGGGGSSSFIAIDDVTYSTHSCPPKDSVCDFENGLCSWSNTQNPSLDWLDWDVTSAQTEMFYNTPPYDRTSNTEGHFLVLPNSDRDTATHNALLLSPHLSSTKGTCLSFWVYQPTIHDTKLTVWRRSEETKQELLTLNEGDRNWKYFSVDITSESEYQIVLEGFKGEKGVLALDDLRYTVGVNCAGQKTDQSSSSSANTGTIVASIVVVIVLLVILAVLLVLYRKNKQSSIMQSSGGSHVSCSGFGNDMYDSGDTAPLEEVSESTGA", "length": 1192, "header": "tr|A0A8M9P3N8-1|A0A8M9P3N8_DANRE Isoform 1 of Apical endosomal glycoprotein isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-11o18.5 PE=1 SV=2 CANONICAL=A0A8M9P3N8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P3N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3N8/entry#A0A8M9P3N8-1", "sequence": { "sequence": "MKTGFMAACFWILVCVLLNVCQRAAVALDGKDCSSSPENRCDFICDCKDCSDEQDCGYLGPKFVCDFEHEGKCGWTAKPAEGAYMWQRQRRGKTLPDSGPSSDYTTGTSTGWFMAVTAVTSDAPQTAILESPTIKHSSPTCRLRLRYFIWDSGHTGMGETPLWGSVRQTDGEQAVVWRPESSSFRGWREDVIYLGRITGPFNMQLHSRRSEGKQGDVAIDHMEFLDCALPVPSESGKCTGGFVQCKRDGCVEEYKVCDGTDDCGDGTDEENCEQNNSCNFEDGLCWWDLRSMASLKWTWTDQMNISLSEPLKGPGRDHSSNTASGRFLYVTKPNFTASDWTTFQSPPLAPTNETHPCRMVMYTHQFGRVSGGLSVLVAERQFYPVWRRGGALGDLWVKAEVEFVVNSTFQILFVAAIRDQPYGGIAVDDIVLSPGCILSNESMPQAGYPKPPDHPCTKDSSKICDFHEDCTNGEDEDQCGDFSYAKGSSGWTDTSIGSQAWDLKVVNTISKEEFLFVTAAPGQQLSEAQTRTPLLGPSGPVCTLQFSYSLTGTNPHIGELAVYVVDSVMGTQPVLWDFAGRTNETTGTWRKEEVYVGARDHRFQLEFRARAKDLSSSALIAVKDVHFVDCSPMFIPSGDISCNFEVNMCGWYQDQTDNYNWKLHSGMDHTVQDGRSLVVDMWDPSLRGLSGRLLSIRQTSKTEHCLSFFYKLYGPNTGALSVKLLFADGSEELLWMRSGAHGNVWHEGHCPVPPQLSAFQLVFEATRSGFDGQLALDDVAFVEGQCSLPTMCSFESQTCGYTSSGRARWVHQNWASSKNGPTTDHSLETENGFYMLAHSSVDILPEGSVTTLTSPVRKGLSHTECVHFWYHTGGDKPGTLSVYVKPSNGDRILLFSSSVTQGQAWRHAQGNVENHGDWQLQFEVKGGGGGSSSFIAIDDVTYSTHSCPPKDSVCDFENGLCSWSNTQNPSLDWLDWDVTSAQTEMFYNTPPYDRTSNTEGHFLVLPNSDRDTATHNALLLSPHLSSTKGTCLSFWVYQPTIHDTKLTVWRRSEETKQELLTLNEGDRNWKYFSVDITSESEYQIVLEGFKGEKGVLALDDLRYTVGVNCAGQKTDQSSSSSANTGTIVASIVVVIVLLVILAVLLVLYRKNKQSSIMQSSGGSHVSCSGFGNDMYDSGDTAPLEEVSESTGA", "length": 1192, "header": "tr|A0A8M9P3N8-1|A0A8M9P3N8_DANRE Isoform 1 of Apical endosomal glycoprotein isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-11o18.5 PE=1 SV=2 CANONICAL=A0A8M9P3N8-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PD58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3N8/entry#A0A8M9PD58-1", "sequence": { "sequence": "MKTGFMAACFWILVCVLLNVCQRAVALDGKDCSSSPENRCDFICDCKDCSDEQDCGYLGPKFVCDFEHEGKCGWTAKPAEGAYMWQRQRRGKTLPDSGPSSDYTTGTSTGWFMAVTAVTSDAPQTAILESPTIKHSSPTCRLRLRYFIWDSGHTGMGETPLWGSVRQTDGEQAVVWRPESSSFRGWREDVIYLGRITGPFNMQLHSRRSEGKQGDVAIDHMEFLDCALPVPSESGKCTGGFVQCKRDGCVEEYKVCDGTDDCGDGTDEENCEQNNSCNFEDGLCWWDLRSMASLKWTWTDQMNISLSEPLKGPGRDHSSNTASGRFLYVTKPNFTASDWTTFQSPPLAPTNETHPCRMVMYTHQFGRVSGGLSVLVAERQFYPVWRRGGALGDLWVKAEVEFVVNSTFQILFVAAIRDQPYGGIAVDDIVLSPGCILSNESMPQAGYPKPPDHPCTKDSSKICDFHEDCTNGEDEDQCGDFSYAKGSSGWTDTSIGSQAWDLKVVNTISKEEFLFVTAAPGQQLSEAQTRTPLLGPSGPVCTLQFSYSLTGTNPHIGELAVYVVDSVMGTQPVLWDFAGRTNETTGTWRKEEVYVGARDHRFQLEFRARAKDLSSSALIAVKDVHFVDCSPMFIPSGDISCNFEVNMCGWYQDQTDNYNWKLHSGMDHTVQDGRSLVVDMWDPSLRGLSGRLLSIRQTSKTEHCLSFFYKLYGPNTGALSVKLLFADGSEELLWMRSGAHGNVWHEGHCPVPPQLSAFQLVFEATRSGFDGQLALDDVAFVEGQCSLPTMCSFESQTCGYTSSGRARWVHQNWASSKNGPTTDHSLETENGFYMLAHSSVDILPEGSVTTLTSPVRKGLSHTECVHFWYHTGGDKPGTLSVYVKPSNGDRILLFSSSVTQGQAWRHAQGNVENHGDWQLQFEVKGGGGGSSSFIAIDDVTYSTHSCPPKDSVCDFENGLCSWSNTQNPSLDWLDWDVTSAQTEMFYNTPPYDRTSNTEGHFLVLPNSDRDTATHNALLLSPHLSSTKGTCLSFWVYQPTIHDTKLTVWRRSEETKQELLTLNEGDRNWKYFSVDITSESEYQIVLEGFKGEKGVLALDDLRYTVGVNCAGQKTDQSSSSSANTGTIVASIVVVIVLLVILAVLLVLYRKNKQSSIMQSSGGSHVSCSGFGNDMYDSGDTAPLEEVSESTGA", "length": 1191, "header": "tr|A0A8M9PD58-1|A0A8M9PD58_DANRE Computationally mapped isoform of Apical endosomal glycoprotein isoform X2 OS=Danio rerio OX=7955 GN=si:dkey-11o18.5 PE=1 SV=2 CANONICAL=A0A8M9P3N8-1" }, "locus": {} }, { "isoform_ac": "A0AC58IAD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3N8/entry#A0AC58IAD7-1", "sequence": { "sequence": "MKTGFMAACFWILVCVLLNVCQRAVALDGKDCSSSPENRCDFICDCKDCSDEQDCGYLGPKFVCDFEHEGKCGWTAKPAEGAYMWQRQRRGKTLPDSGPSSDYTTGTSTGWFMAVTAVTSDAPQTAILESPTIKHSSPTCRLRLRYFIWDSGHTGMGETPLWGSVRQTDGEQAVVWRPESSSFRGWREDVIYLGRITGPFNMQLHSRRSEGKQGDVAIDHMEFLDCALPVPSESGKCTGGFVQCKRDGCVEEYKVCDGTDDCGDGTDEENCEQNNSCNFEDGLCWWDLRSMASLKWTWTDQMNISLSEPLKGPGRDHSSNTASGRFLYVTKPNFTASDWTTFQSPPLAPTNETHPCRMVMYTHQFGRVSGGLSVLVAERQFYPVWRRGGALGDLWVKAEVEFVVNSTFQILFVAAIRDQPYGGIAVDDIVLSPGCILSNESMPQAGYPKPPDHPCTKDSSKICDFHEDCTNGEDEDQCGDFSYAKGSSGWTDTSIGSQAWDLKVVNTISKEEFLFVTAAPGQQLSEAQTRTPLLGPSGPVCTLQFSYSLTGTNPHIGELAVYVVDSVMGTQPVLWDFAGRTNETTGTWRKEEVYVGARDHRFQLEFRARAKDLSSSALIAVKDVHFVDCSPMFIPSGDISCNFEVNMCGWYQDQTDNYNWKLHSGMDHTVQDGQDTSDDE", "length": 680, "header": "tr|A0AC58IAD7-1|A0AC58IAD7_DANRE Computationally mapped isoform of Apical endosomal glycoprotein isoform X3 OS=Danio rerio OX=7955 GN=si:dkey-11o18.5 PE=1 SV=1 CANONICAL=A0A8M9P3N8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:797166", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797166", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2AJA7-1", "protein_name": "Apical endosomal glycoprotein", "gene_name": "Mamdc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCLPSHLLSTWVLFMAAQSLGKTWLPNHCRSPIKAVCNFVCDCGDCSDETQCGFHGASTIPSTSFTCNFEQDSCGWQDISTSGYRWLRDRAGAVLHGPGPHSDHTHGTDLGWYMAVGTHSGKEPSTATLRSPVMREAAPTCELRLWYHIASRDVAELRLDLTHGVETLTLWQTSGPWGPGWQELAVNTGRIQGDFKVTFSATRNATHRGAVALDDVEFRDCGLPIPQARCPLGHHHCQNKACVEPHQLCDGEDNCGDRSDEDPLICSHHMATDFETGLGPWNQLEGWTRNHSAGSMVSPAWPHRDHSRNSAYGFFLISVAKPGTTAVLYSPEFQGSVSNNCSFTFYYYLHGSEASHFQLFLQAQGLNTPQVPVLLRSRHGELGTAWVRDRVDIQSAHPFRILLAGETGPGGVVGLDDLIMSSHCMLVPAMSTLQSSLSGPVPLALYPQTSIKLPQQTCEPGHLSCGDLCVPPEQLCDFQKHCAEGEDEHKCGTTDFESASAGGWEDISVGKLQWQWVEAQEKSKPAGDANRDAPGHFLSLQKAWGQLRSEARALTPALGPSGPHCELHMAYYFQSHPQGFLALVVVENGFRELLWQAPGGGSGSWTEEKIILGARRRPFQLEFVSLVDLDGPGQQGAGVDNVTLRDCNPMVTTESDQELSCNFERDSCSWHTGHLTDAHWHRIKSHGSQLDHTTGQGFFMFLDPTDPPARGQGALLLTRPQVPVVPKECLSFWYRLYGPQIGTLCLAMRREREEDILLWSRSGTHGNRWHQAWVTLHHQPEASTKYQLLFEGLRNGYHGTMALDDIAVRPGPCWAPKSCSFEDSDCGFSPGGWGLWTHQSNASGLASWGPWIDHTTGTAQGHYMVVDTSPNVLPKGHVAALTSEEHQPLSQPACLTFWYHMSVPNPGTLRVHVEESTRRQELSISAHGRSAWRLGSVNVQAEQAWKVVFEAVAAGVEYSYMALDDISLQDGPCPQPGSCDFETGLCGWSHLPWPSLGGYSWDWSSGATPSRYPQPSVDHTLGTEAGHFAFFETSVLGPGGQAAWLRSEPLPATTVSCLRFWYYMGFPEHFYKGELRVLLSSARGQLAVWYQGGHLRDQWLQVQIELSNSEEFQIVFEATLGGQPALGPIAIDDVQYLAGQQCKQPSPSQGEVAAPVSVPVAVGGALLFFMFLVLMGLGGWHWLQKQHCPGQRSTDAAASGFANILFNADHVTLPESITSNPQSPPDLA", "length": 1228 }, "evidence": [ { "id": "RGD:708583", "url": "https://alliancegenome.org/gene/RGD:708583#orthology", "database": "AGR" }, { "id": "HGNC:24083", "url": "https://alliancegenome.org/gene/HGNC:24083#orthology", "database": "AGR" }, { "id": "MGI:2685841", "url": "https://alliancegenome.org/gene/MGI:2685841#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-110", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-110#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63191-1", "protein_name": "Apical endosomal glycoprotein", "gene_name": "Mamdc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCLPSCLLSIWVLFMAAQSLGKTWVPDHCRSPTEATCNFVCDCGDCSDEAQCGFHGASTTPNTPFTCNFEQDPCGWQDISTSGYRWLRDRAGAGLDSSGPHSDHTRGTDLGWYMAVGTHSGKEPSTRTLRSPVMREAAPTCELRLWYHTDSRDVAELRLDLTHGMETLTLWQSSGPWGPWPGRELAVNTGRIQGDFKVTFSATRNATHRGAVALDDMEFWDCGLPIPQARCPLGHHHCQNKACVEPHQLCDGEDNCGDSSDEDPLICSHHMATDFETGLGPWTQLEGWTRNFSAGSMVSPAWPHRDHSRNSAYGFFLVSVAKPGTTAVLYSPEFQGSVSYNCSFTFYYYLHGSEANQFQLFVQAQGLNTTQPPVLLRSRHGELGTAWVRDRVNIQSAHPFRILLAGETGPGGFVGLDDLIMSNHCILVPGMSTLQSSLSGPVPLALYPQTSIKRTCDAGHLSCDELCVPPEQLCDFQQHCAEGEDEEKCGTTDFESASAGGWEDISIGKLQWQRAEAQESGKPARDTNRNAPGHFLSLRKAWGQLRSEARALTPTLGPSGPHCELHMTYYFHSHPQGFLALAVVENGFRELLWQAPSSSSGGWTLQKILLGARRWPFQLEFVSLVDLDGPGQQGAGVDNVTLRDCNPMVTTESDQEVSCNFERDSCSWHTGHLTDAHWHRVKSHGSQYDHTTGQGFFMFLDPMDPPARGQGALLLTRPQVPVVPKECLSFWYHLHGPQIGTLCLAMRREGEEDTLLWSRSGTHGNRWHQAWVTLHHQLQPSTKYQLLFEGLRDGYHGTMGLDDMAVRPGPCWAAKRCSFEDSDCGFSPGDWGLWTRQNNASGLGPWGPWIDHTTGTAQGHYMVVDTSPNLLPKGHVASLTSEEHPPLSRPACLSFWYHLSFHNPGTLRVFVEESTRRQELSISGHGGFAWRLGSVNVQAEQAWKVVFEAMASGVEHSYMALDDISLQDGPCAQPGSCDFESGLCGWSHLPWPGLGGYSWDWSSGATPSRYPRPSVDHTVGTEAGHFAFFETSVLGPGGQAAWLGSEPLPATAVSCLHFWYYMGFPAHFYKGELRVLLSSTQGQLAVWHRGGHLRDQWLQVQIEVSSSEEFQIVFEATLGGQPALGPIALDDVEYLAGQHCKQPTPSQGRVAAPVSVPVAVGGALLLFLLLLGLGGWHWLQKQHLPCQSTDAAASGFDNILFNADQVTLPESITSNP", "length": 1216 }, "evidence": [ { "id": "RGD:708583", "url": "https://alliancegenome.org/gene/RGD:708583#orthology", "database": "AGR" }, { "id": "HGNC:24083", "url": "https://alliancegenome.org/gene/HGNC:24083#orthology", "database": "AGR" }, { "id": "MGI:2685841", "url": "https://alliancegenome.org/gene/MGI:2685841#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-110", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-110#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6UXC1-1", "protein_name": "Apical endosomal glycoprotein", "gene_name": "MAMDC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLSSHLLPALVLFLAGSSGWAWVPNHCRSPGQAVCNFVCDCRDCSDEAQCGYHGASPTLGAPFACDFEQDPCGWRDISTSGYSWLRDRAGAALEGPGPHSDHTLGTDLGWYMAVGTHRGKEASTAALRSPTLREAASSCKLRLWYHAASGDVAELRVELTHGAETLTLWQSTGPWGPGWQELAVTTGRIRGDFRVTFSATRNATHRGAVALDDLEFWDCGLPTPQANCPPGHHHCQNKVCVEPQQLCDGEDNCGDLSDENPLTCGRHIATDFETGLGPWNRSEGWSRNHRAGGPERPSWPRRDHSRNSAQGSFLVSVAEPGTPAILSSPEFQASGTSNCSLVFYQYLSGSEAGCLQLFLQTLGPGAPRAPVLLRRRRGELGTAWVRDRVDIQSAYPFQILLAGQTGPGGVVGLDDLILSDHCRPVSEVSTLQPLPPGPRAPAPQPLPPSSRLQDSCKQGHLACGDLCVPPEQLCDFEEQCAGGEDEQACGTTDFESPEAGGWEDASVGRLQWRRVSAQESQGSSAAAAGHFLSLQRAWGQLGAEARVLTPLLGPSGPSCELHLAYYLQSQPRGFLALVVVDNGSRELAWQALSSSAGIWKVDKVLLGARRRPFRLEFVGLVDLDGPDQQGAGVDNVTLRDCSPTVTTERDREVSCNFERDTCSWYPGHLSDTHWRWVESRGPDHDHTTGQGHFVLLDPTDPLAWGHSAHLLSRPQVPAAPTECLSFWYHLHGPQIGTLRLAMRREGEETHLWSRSGTQGNRWHEAWATLSHQPGSHAQYQLLFEGLRDGYHGTMALDDVAVRPGPCWAPNYCSFEDSDCGFSPGGQGLWRRQANASGHAAWGPPTDHTTETAQGHYMVVDTSPDALPRGQTASLTSKEHRPLAQPACLTFWYHGSLRSPGTLRVYLEERGRHQVLSLSAHGGLAWRLGSMDVQAERAWRVVFEAVAAGVAHSYVALDDLLLQDGPCPQPGSCDFESGLCGWSHLAWPGLGGYSWDWGGGATPSRYPQPPVDHTLGTEAGHFAFFETGVLGPGGRAAWLRSEPLPATPASCLRFWYHMGFPEHFYKGELKVLLHSAQGQLAVWGAGGHRRHQWLEAQVEVASAKEFQIVFEATLGGQPALGPIALDDVEYLAGQHCQQPAPSPGNTAAPGSVPAVVGSALLLLMLLVLLGLGGRRWLQKKGSCPFQSNTEATAPGFDNILFNADGVTLPASVTSDP", "length": 1216 }, "evidence": [ { "id": "RGD:708583", "url": "https://alliancegenome.org/gene/RGD:708583#orthology", "database": "AGR" }, { "id": "HGNC:24083", "url": "https://alliancegenome.org/gene/HGNC:24083#orthology", "database": "AGR" }, { "id": "MGI:2685841", "url": "https://alliancegenome.org/gene/MGI:2685841#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-110", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-110#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P3N8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3N8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 275, "end_pos": 277, "annotation": "n_glycosylation_sequon" }, { 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Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324912" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P439", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P439" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "grxcr2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P439", "locus": {} } ], "crossref": [ { "id": "A0A8M9P439", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P439", "database": "AlphaFoldDB", "categories": [] }, { "id": "100535155", "url": "https://www.ncbi.nlm.nih.gov/gene/100535155", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033023", "url": 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annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325127.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325127", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325127" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4G8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4G8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438256", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4G8", "locus": {} } ], "crossref": [ { "id": "A0A8M9P4G8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P4G8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110438256", "url": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P4L2-1", "uniprot_ac": "A0A8M9P4L2", "uniprot_id": "A0A8M9P4L2_DANRE", "mass": { "chemical_mass": 41474.0, "monoisotopic_mass": 41474.0 }, "refseq": { "ac": "XP_073793143", "name": "caytaxin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073793143" }, "gene_names": [ { "name": "atcaya", "type": "recommended", "evidence": [ { "id": "A0A8M9P4L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4L2" } ] }, { "name": "atcaya", "type": "synonym", "evidence": [ { "id": "XP_073793143", "database": "RefSeq", "url": 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This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073793143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073793143" } ] } ], "disease": [ { "disease_id": "DOID:0050753", "recommended_name": { "id": "DOID:0050753", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050753", "name": "cerebellar ataxia", "description": "A hereditary ataxia that is characterized by ataxia originating in the cerebellum." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050753", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050753" } ] }, { "disease_id": "DOID:0060694", "recommended_name": { "id": "DOID:0060694", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060694", "name": "Cayman type cerebellar ataxia", "description": "An autosomal recessive cerebellar ataxia characterized by marked autosomal recessive inheritance, psychomotor retardation, cerebellar dysfunction including nystagmus, intention tremor, dysarthria, and wide-based ataxic gait, hypotonia and the absence of retinal abnormalities that has_material_basis_in mutation in the ATCAY gene on chromosome 19p13.3." }, "synonyms": [ { "id": "DOID:0060694", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060694", "name": "Cayman cerebellar ataxia", "description": "" }, { "id": "MONDO:0011025", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011025", "name": "Cayman type cerebellar ataxia", "description": "Cerebellar ataxia, Cayman type is characterized by psychomotor retardation, hypotonia and cerebellar dysfunction (nystagmus, ataxic gait, truncal ataxia, dysarthric speech and intention tremor), associated with cerebellar hypoplasia." }, { "id": "MONDO:0011025", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011025", "name": "Cayman ataxia", "description": "" }, { "id": "MONDO:0011025", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011025", "name": "Cayman type cerebellar ataxia", "description": "" }, { "id": "MONDO:0011025", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011025", "name": "ataxia, cerebellar, Cayman type", "description": "" }, { "id": "MONDO:0011025", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011025", "name": "ATCAY", "description": "" }, { "id": "MONDO:0011025", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011025", "name": "cerebellar ataxia, Cayman type", "description": "" }, { "id": "MIM:601238", "resource": "MIM", "url": "https://www.omim.org/entry/601238", "name": "Cerebellar ataxia, cayman type", "description": "Cerebellar ataxia, cayman type" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060694", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060694" } ] }, { "disease_id": "DOID:543", "recommended_name": { "id": "DOID:543", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:543", "name": "dystonia", "description": "A movement disease that is characterized by involuntary muscle contractions causing repetitive or twisting movements." }, "synonyms": [ { "id": "DOID:543", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:543", "name": "dystonic disease", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "early-onset generalized limb-onset dystonia", "description": "A rare movement disorder characterized by involuntary, repetitive, sustained muscle contractions or postures involving one or more sites of the body." }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "DYT-TOR1A", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "DYT1", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "EOTD", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "Oppenheim dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "Oppenheim's dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "dystonia musculorum deformans", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "dystonia-1, torsion", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "early onset primary dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "early onset torsion dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "early-onset generalised torsion dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "early-onset generalized limb-onset dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "early-onset generalized torsion dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "early-onset primary dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "early-onset torsion dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "idiopathic dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "torsion dystonia type 1", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "DYT-TOR1A dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "Dyt1", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "Early-onset Primary dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "Early-onset torsion dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "Primary torsion dystonia", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "dystonia 1", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "dystonia 1, torsion, Autosomal dominant", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "dystonia 1, torsion, autosomal dominant", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "dystonia musculorum deformans 1", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "idiopathic dystonia DYT1", "description": "" }, { "id": "MONDO:0007492", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007492", "name": "torsion dystonia 1, autosomal dominant", "description": "" }, { "id": "MIM:128100", "resource": "MIM", "url": "https://www.omim.org/entry/128100", "name": "Dystonia 1, torsion, autosomal dominant", "description": "Dystonia 1, torsion, autosomal dominant" } ], "unlinked_id_list": [ "DOID:0050837", "DOID:0050838" ], "evidence": [ { "id": "543", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:543" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4L2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4L2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "atcaya", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4L2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-185", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-185", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P4L2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P4L2", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000071678", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000071678", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00170", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00170", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "565827", "url": "https://www.ncbi.nlm.nih.gov/gene/565827", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036865", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036865", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "GRDEWQD", "url": "https://omabrowser.org/oma/group/GRDEWQD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P4L2", "url": "https://www.orthodb.org/?gene=A0A8M9P4L2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12112:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12112:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12496", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12496", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13716", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13716", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073793143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073793143", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P4L2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4L2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P4L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4L2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ACD6B6P0", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B6P0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0ACD6B6P0-1", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B6P0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-185", "url": "https://zfin.org/ZDB-GENE-070705-185", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGSVDFGPLLEIIEARDEWLDDDFPRPLPAEGDMDSSCALSEGRTSPPNSLLIGGAGGGGAHRKRRTLVAPDMNLSLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFITNGNDLEWEDDTPVASAKAPPADSDADGEGVDGTGANGRLWRTVIIGEQEHRIDMQVIRPYLRVISHGGYYGEGLNAIIVFTACYLPDSSCPDYHYLMENLFLYVVSSLEMLVAEDYLIIYMNGGTPRSKMPGISWLKKCYQMIDRRLRKNLKSLIITHPSWFIRTVIAISKPFISVKFMNKIRYVHSLEELEKFVPMDHIHIPECILQYEEERLNARKERMEQEQKEQQHQEQQQKPTNPERTTAIEEPGL", "length": 367, "header": "tr|A0A8M9P4L2-1|A0A8M9P4L2_DANRE Isoform 1 of Caytaxin isoform X1 OS=Danio rerio OX=7955 GN=atcaya PE=4 SV=2 CANONICAL=A0A8M9P4L2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P4L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4L2/entry#A0A8M9P4L2-1", "sequence": { "sequence": "MGSVDFGPLLEIIEARDEWLDDDFPRPLPAEGDMDSSCALSEGRTSPPNSLLIGGAGGGGAHRKRRTLVAPDMNLSLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFITNGNDLEWEDDTPVASAKAPPADSDADGEGVDGTGANGRLWRTVIIGEQEHRIDMQVIRPYLRVISHGGYYGEGLNAIIVFTACYLPDSSCPDYHYLMENLFLYVVSSLEMLVAEDYLIIYMNGGTPRSKMPGISWLKKCYQMIDRRLRKNLKSLIITHPSWFIRTVIAISKPFISVKFMNKIRYVHSLEELEKFVPMDHIHIPECILQYEEERLNARKERMEQEQKEQQHQEQQQKPTNPERTTAIEEPGL", "length": 367, "header": "tr|A0A8M9P4L2-1|A0A8M9P4L2_DANRE Isoform 1 of Caytaxin isoform X1 OS=Danio rerio OX=7955 GN=atcaya PE=4 SV=2 CANONICAL=A0A8M9P4L2-1" }, "locus": {} }, { "isoform_ac": "A0ACD6B6P0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4L2/entry#A0ACD6B6P0-1", "sequence": { "sequence": "MDSSCALSEGRTSPPNSLLIGGAGGGGAHRKRRTLVAPDMNLSLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFITNGNDLEWEDDTPVASAKAPPADSDADGEGVDGTGANGRLWRTVIIGEQEHRIDMQVIRPYLRVISHGGYYGEGLNAIIVFTACYLPDSSCPDYHYLMENLFLYVVSSLEMLVAEDYLIIYMNGGTPRSKMPGISWLKKCYQMIDRRLRKNLKSLIITHPSWFIRTVIAISKPFISVKFMNKIRYVHSLEELEKFVPMDHIHIPECILQYEEERLNARKERMEQEQKEQQHQEQQQKPTNPERTTAIEEPGL", "length": 334, "header": "tr|A0ACD6B6P0-1|A0ACD6B6P0_DANRE Computationally mapped isoform of Caytaxin isoform X2 OS=Danio rerio OX=7955 GN=atcaya PE=4 SV=1 CANONICAL=A0A8M9P4L2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AVU1-1", "protein_name": "BCL2 interacting protein 2", "gene_name": "Bnip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGVELKEEWQDEDFPIPLPEDDSIEADILDVTDPDRQPGSLEVNGNKVRKKLVAPDISLTLDPGEDSLWSDDLDEGGEVDLDGLDTPSENSDEFEWEDDLPKPKTTEVIRKGSITEYAATEEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYGDGLNAIVVFAVCFMPESGQPNYRYLMDNLFKYVIGTLELLVAENYMIIYLNGATTRRKMPSLGWLRRCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQVDQELNGKQEPPKSEQ", "length": 314 }, "evidence": [ { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AB32T7U5-1", "protein_name": "Caytaxin", "gene_name": "atcayb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGTTEATLRMENMEVKDEWQDDDFPRPLPEDGDLDGLTDNSHHGALTADHLDSVRQKRRTLIAPDINLSLDKSEGSVLSDDFLETPDDLDINVDDIETPDDDSLGSANNGTELEWEDDTPVASAKGPGGDDGDGTGRLWRSVIIGDQEHRIDMQVIRPYLRVVTHGGYYGEGLNAIIVFAACYLPDSGCADYNYIMENLFLYVISSLEALVAEDYMIIYLNGATPRRRMPGISWLKRCYQMIERRLRKNLKCLIIAHPTWFIRTVLAISRPFVNVKFMDKIRYVQSLQELAQIVPMEHVQIPECVLQFDEERIKVQRERTEQVSKTSERPPSVAAEACP", "length": 339 }, "evidence": [ { "id": "HGNC:779", "url": "https://alliancegenome.org/gene/HGNC:779#orthology", "database": "AGR" }, { "id": "RGD:1309312", "url": "https://alliancegenome.org/gene/RGD:1309312#orthology", "database": "AGR" }, { "id": "MGI:2448730", "url": "https://alliancegenome.org/gene/MGI:2448730#orthology", "database": "AGR" }, { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TUF7-1", "protein_name": "Protein prune homolog 2", "gene_name": "prune2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDQTYESKMSFEGAESRPAPPTSLPLQGQGGVSSQRKKLSAPRISLSLDQSEDDLFDTPDDLDINVDDLDTPDEADYTDHEIDWEEPQASQRDSVKETVESIPTYSAEEERQDSKLWRTVIIGEQEHRINMKSIEPYQKVISHGGYYSNGANAIIVFAACFLPDSDREDYHEIMENLFLYVISTLELMVAEDYMIVYLNGATPHRRMPGLNWLKRCYQMIDRRLRKNLKSFIIVHPSWFIRTILAITKPFISSKFSSKIKYVNSLAELEELIPMEYVHIPECIVSLLLVQPRWIGRWQKRRGLPDPQDPEIQMLGGTIIVPHRLGGVQHGGKILDQSKGYSRPNSVE", "length": 347 }, "evidence": [ { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O54940-1", "protein_name": "BCL2/adenovirus E1B 19 kDa protein-interacting protein 2", "gene_name": "Bnip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGVELKEEWQDEDFPIPLPEDDSIEADTLDGTDPDRQPGSLEVNGNKVRKKLMAPDISLTLDPGEDSLWSDDLDEAGEVDLEGLDTPSENSDEFEWEDDLPKPKTTEVIRKGSITEYTATEEKGDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYGDGLNAIVVFAVCFMPESGQPNYRYLMDNLFKYVIGTLELLVAENYMIIYLNGATTRRKMPSLGWLRRCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQYEEEKFKKRQKRVDQELNGKQEPPKSEQ", "length": 326 }, "evidence": [ { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q12982-1", "protein_name": "BCL2/adenovirus E1B 19 kDa protein-interacting protein 2", "gene_name": "BNIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGVELKEEWQDEDFPIPLPEDDSIEADILAITGPEDQPGSLEVNGNKVRKKLMAPDISLTLDPSDGSVLSDDLDESGEIDLDGLDTPSENSNEFEWEDDLPKPKTTEVIRKGSITEYTAAEEKEDGRRWRMFRIGEQDHRVDMKAIEPYKKVISHGGYYGDGLNAIVVFAVCFMPESSQPNYRYLMDNLFKYVIGTLELLVAENYMIVYLNGATTRRKMPSLGWLRKCYQQIDRRLRKNLKSLIIVHPSWFIRTLLAVTRPFISSKFSQKIRYVFNLAELAELVPMEYVGIPECIKQVDQELNGKQDEPKNEQ", "length": 314 }, "evidence": [ { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1M168-1", "protein_name": "Caytaxin", "gene_name": "Atcay", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTTEATLRMENVDVRDEWQDEDLPRPLPEDTGEDHLGGTVEDSSSPPSTLNLSGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWEDDTPVATAKNMPGDSADLFGDGSGEDGSAANGRLWRTVIIGEQEHRIDLHMIRPYMKVVTHGGYYGEGLNAIIVFAACFLPDSSSPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYHMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFISVKFISKIQYVHSLEELEQLIPMEHVQLPACVLQYEEQRLRAKRESARPPQPEFLLPRSEEKPETVEEEDRAAEVTEDQETSMS", "length": 372 }, "evidence": [ { "id": "HGNC:779", "url": "https://alliancegenome.org/gene/HGNC:779#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-185", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-185#orthology", "database": "AGR" }, { "id": "RGD:1309312", "url": "https://alliancegenome.org/gene/RGD:1309312#orthology", "database": "AGR" }, { "id": "MGI:2448730", "url": "https://alliancegenome.org/gene/MGI:2448730#orthology", "database": "AGR" }, { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q52KR3-1", "protein_name": "Protein prune homolog 2", "gene_name": "Prune2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEFLQRAKSKLDRSKQLEQVHAVIGPKSCDLDSLISAFTYAYFLDKVSPPGVLCLPVLNIPRTEFNYFTETRFILEELNIPESFHIFRDEINLHQLNDEGKLSITLVGSHVLGSEDRTLESAVVRVINPGEQSDGELGFPETSSSLVLKELLREAPELITQQLAHLLRGSILFTWMSMDPELPEKQEEILSILEEQFPNLPPRDDIINVLQESQLSAQGLSLEQTMLKDLKELSDGEIKVAISTVNMTLEDYLLHGNITSDLKAFTDKFGFDVLILISSFTWEEQQRQQIAVYSQNLELCSQICCELEESQNPCLELEPFECGCDEILVYQQEDPSVTSDQVFLLLKEVINRRCAEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPELNDSNQAQADGNIDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGDGGAPHHSLLPGFDSYSPIPEGIVAEEHAHSGEHSEHFDLFNFDSAPIASEQSQPSSHSADYSPEDDFPNSDSSEGNLSAGPKGLGEMGINMSNYSSSSLLSEAGKDSLVEFDEEFIQRQESSGDNSERNLSLTCFAGEEPSSPERLKNPGKMIPPTPMNSFVEISPSNEEPTPLYPEDIIQNAIDTGHLGPPQARARCRSWWGGLEIDSKNVVDTWNASEQESVFQSPEPWKDPKPEPVERRTSDSTFQPKSLEFSKSDPWESEFGQPELGNKEAQDQKEESLQYQHLPTVRPHLTDASPHGTNHLIEDFAALWHSGHSPTTMPEPWGNPTDAGEAAVTMSFPTWGAFDKEEDNADTLKNTWNLHPTNNETPSGQEPSEWAMGQSGFSFPAADLLDNPLIEVNKDAAPEIWGKNNSSKDTSLTSGSPTSDLGQTWNNSKLPGEDQNGLVDPKATGKVYEKEGSWSLFEESAKKRGADVLAPWEDSFLSYKCSDYSASNIGEDSVPSPLDTNYSTSDSYTSPTYAGDEKEIANKPVDKDNGFEAKDAEFPAEGLEVLATSSQQSQRNRIGSGPGNLDMWALPHTEDKPEGNDAHHPDSDALKTEHAEDKNASMEDDVRESSPSSYDDPSMMRLYEANRQLTLLHSNTNSRQAAPDSLDTWNRVTLEDTQSTATISDMDNDLDWDDCSGGVAISGDGQAEGYIAANSEPETRFSVKQLEPWGTEHQEANQVDWDLSASAEPTGDPGPSEYQTLNEKTGQLIANSIWDSVMGDKNMPSFRLPSPPNTVDMEHGTWPSESPRHSNGKDSHMLEASRLSESGGLTSQPVNQDTWGDSQGDTASSVTGLASPEHFAQSDPWTGHTYGQSESEIEGLVASDCEHLDKEAALGSGVNGAPWAFGKKPRDQEFSSSDAFEHQDISSASGKISSLSVTSSPQSEEPGEALEVEKEPFILDSLAVQTETFTWDLQSKDTHEESLVDHRNLGEANTTLDRINPMKNRPLSGMELEKTEACTILKPERANGKLLYESSQDFGVWDGPMDSDVWDSHISYETAMNSTGQRTEERSLEALSPGNYDRDSLSSGCTHSSASSPDLHDSSVALSSWTYGPSAEHQKENHDDANKQIHQESELFTTEAHVDVITEMKDFVENREDGFGKMSNQEDPQFPEIPNDPFNSGPSSSSSSLGADKYSEYSHAYQEGDLTTKRQEENELGFLEIVEPEGTRIISTSSGSGNDSGGDEELLEKELHLATVAQSEAGACTSLHEPAFSATEHSKPEFSVFVGSLESIEKENKSSPFSDSQQSSPGQWILSPLMQADTQDTCKEETRAAETGTMDTTWHGSASTEAKNGDPDKLEMLGFSADSTEWWNAGAQEGRANAGMSAEELSNSEGELEPTSPVFQNAGPWSLPIQNDSEPVDTGSTNPFRGKLKSPVLDSHGDKSQEKLWNIQPKQLDSDANQLSQLVILDQMKDKDSGQQTAMSPAAGDLPAETLTQGQGRESMLSVWDRAEPALTHRDENGCVSTGVSPTECQQENQWEPEKPYLSHVTHSSTPTENALESNAPTQLMRKLDSDWNSPSPSEPQHNFVPDILHGNFEEGGQLASASPDLWMDVKQPFSFKVDSENPDILTHCDHDSNSQASSSPDVCHDSEGEQKMEKHTAVYLGLEVEPSEFSLTEPNMNDEPTWEPEQESLPHNSELHSEHAMPLPPIDSQNDINNSSKPASSRSSPEPSDMRGDNNTSVTSMEEDTNPEVEAVDSVTIPGHFPRSEDADTFEAHQEVSVEVDDSWVSKDLCPESQTGTRALLDCEQPFASESPAVLTDIFLTSDTCLDVSEAALDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDAGKQDVCSSEASWGDFEYDAMGQNIDEELMREPEHFLYGGDLPSEESALKQSLTPYTPPFDLSYLTEPTGCTETAQGAESPGDESLGSDAAEMLLSALPDHREEDKAETNIRKPRYQMTVLHIHEDPEALSSPVGGTGSNNESSPSNIDWEIETDNSDSPAGGDMKPPNGKEILELEEDEKVIPTKGPKQTELEYKEEKQPEQSEDHQVLAVDYILVSHEKDSPLKPEAREARENIPELEQLSIGSRETGLPETQLSGTPDTCQSEFLNDVKVHSAERMSSSSNHESASLENPAQDQSWMVLSHSEVGDPPTETRDSGPESPGRTPEPFLSLSLDKGPKSQVLERNKPLNSLALEEVAGLSSQSRNIERQGQAGLDAVPTQAATHDNEWEMLSPQLSRKNRNPPQEMEEETQCPEPGPRKPRLKGPPSEDEGMDIHFEEGVLSPSAADMRPEPPNSLDLNGSHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTNHEDPTANKSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVTSLSELSGLIPMDCIHIPESIIKYDEEKSFKRSVRLDEELREASEAAKTSCLYNDPEMSSMEKDIDMKLKEKP", "length": 3084 }, "evidence": [ { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5BJR4-1", "protein_name": "Protein prune homolog 2", "gene_name": "Prune2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDIHFEEGVLSPSATDMRPEPPNSLDLNGSHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYPGHEDPMANRSSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRKMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVSSLSELSGLIPMDCIHIPESIIKYDEEKSFKRSVRTSCLYNDPEMTSMEKDIDMKLKEKP", "length": 322 }, "evidence": [ { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z465-1", "protein_name": "Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein", "gene_name": "BNIPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTIQEAGKKTDVGVREIAEAPELGAALRHGELELKEEWQDEEFPRLLPEEAGTSEDPEDPKGDSQAAAGTPSTLALCGQRPMRKRLSAPELRLSLTKGPGNDGASPTQSAPSSPDGSSDLEIDELETPSDSEQLDSGHEFEWEDELPRAEGLGTSETAERLGRGCMWDVTGEDGHHWRVFRMGPREQRVDMTVIEPYKKVLSHGGYHGDGLNAVILFASCYLPRSSIPNYTYVMEHLFRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLRKNLRALVVVHATWYVKAFLALLRPFISSKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQLDRDLHGSGGT", "length": 357 }, "evidence": [ { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86WG3-1", "protein_name": "Caytaxin", "gene_name": "ATCAY", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTTEATLRMENVDVKEEWQDEDLPRPLPEETGVELLGSPVEDTSSPPNTLNFNGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWEDDTPVATAKNMPGDSADLFGDGTTEDGSAANGRLWRTVIIGEQEHRIDLHMIRPYMKVVTHGGYYGEGLNAIIVFAACFLPDSSLPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYQMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFISVKFINKIQYVHSLEDLEQLIPMEHVQIPDCVLQYEEERLKARRESARPQPEFVLPRSEEKPEVAPVENRSALVSEDQETSMS", "length": 371 }, "evidence": [ { "id": "HGNC:779", "url": "https://alliancegenome.org/gene/HGNC:779#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-185", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-185#orthology", "database": "AGR" }, { "id": "RGD:1309312", "url": "https://alliancegenome.org/gene/RGD:1309312#orthology", "database": "AGR" }, { "id": "MGI:2448730", "url": "https://alliancegenome.org/gene/MGI:2448730#orthology", "database": "AGR" }, { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BHE3-1", "protein_name": "Caytaxin", "gene_name": "Atcay", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGTTEATLRMENVDVRDEWQDEDLPRPLPEDTGVERLGGAVEDSSSPPSTLNLSGAHRKRKTLVAPEINISLDQSEGSLLSDDFLDTPDDLDINVDDIETPDETDSLEFLGNGNELEWEDDTPVATAKNMPGDSADLFGDGSAEDGSAANGRLWRTVIIGEQEHRIDLHMIRPYMKVVTHGGYYGEGLNAIIVFAACFLPDSSSPDYHYIMENLFLYVISSLELLVAEDYMIVYLNGATPRRRMPGIGWLKKCYHMIDRRLRKNLKSLIIVHPSWFIRTVLAISRPFISVKFISKIQYVHSLEELERLIPMEHVQLPDCVLQYEEQRLRAKRESTRPPQPEFLLPRSEEKPETVEEEDRAAEATEDQETSMS", "length": 372 }, "evidence": [ { "id": "HGNC:779", "url": "https://alliancegenome.org/gene/HGNC:779#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-185", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-185#orthology", "database": "AGR" }, { "id": "RGD:1309312", "url": "https://alliancegenome.org/gene/RGD:1309312#orthology", "database": "AGR" }, { "id": "MGI:2448730", "url": "https://alliancegenome.org/gene/MGI:2448730#orthology", "database": "AGR" }, { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUY3-1", "protein_name": "Protein prune homolog 2", "gene_name": "PRUNE2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEFLQRAKSKLNRSKRLEKVHVVIGPKSCDLDSLISTFTYAYFLDKVSPPGVLCLPVLNIPRTEFNYFTETRFILEELNISESFHIFRDEINLHQLNDEGKLSITLVGSSVLASEDKTLESAVVKVINPVEQSDANVEFRESSSSLVLKEILQEAPELITEQLAHRLRGSILFKWMTMESEKISEKQEEILSILEEKFPNLPPREDIINVLQETQFSAQGLSIEQTMLKDLKELSDGEIKVAISTVSMNLENCLFHSNITSDLKAFTDKFGFDVLILFSSYLSEEQQPRRQIAVYSENMELCSQICCELEECQNPCLELEPFDCGCDEILVYQQEDPSVTCDQVVLVVKEVINRRCPEMVSNSRTSSTEAVAGSAPLSQGSSGIMELYGSDIEPQPSSVNFIENPPDLNDSNQAQVDANVDLVSPDSGLATIRSSRSSKESSVFLSDDSPVGEGAGPHHTLLPGLDSYSPIPEGAVAEEHAWSGEHGEHFDLFNFDPAPMASGQSQQSSHSADYSPADDFFPNSDLSEGQLPAGPEGLDGMGTNMSNYSSSSLLSGAGKDSLVEHDEEFVQRQDSPRDNSERNLSLTDFVGDESPSPERLKNTGKRIPPTPMNSLVESSPSTEEPASLYTEDMTQKATDTGHMGPPQTHARCSSWWGGLEIDSKNIADAWSSSEQESVFQSPESWKEHKPSSIDRRASDSVFQPKSLEFTKSGPWESEFGQPELGSNDIQDKNEESLPFQNLPMEKSPLPNTSPQGTNHLIEDFASLWHSGRSPTAMPEPWGNPTDDGEPAAVAPFPAWSAFGKEDHDEALKNTWNLHPTSSKTPSVRDPNEWAMAKSGFAFSSSELLDNSPSEINNEAAPEIWGKKNNDSRDHIFAPGNPSSDLDHTWTNSKPPKEDQNGLVDPKTRGKVYEKVDSWNLFEENMKKGGSDVLVPWEDSFLSYKCSDYSASNLGEDSVPSPLDTNYSTSDSYTSPTFAGDEKETEHKPFAKEEGFESKDGNSTAEETDIPPQSLQQSSRNRISSGPGNLDMWASPHTDNSSEINTTHNLDENELKTEHTDGKNISMEDDVGESSQSSYDDPSMMQLYNETNRQLTLLHSSTNSRQTAPDSLDLWNRVILEDTQSTATISDMDNDLDWDDCSGGAAIPSDGQTEGYMAEGSEPETRFTVRQLEPWGLEYQEANQVDWELPASDEHTKDSAPSEHHTLNEKSGQLIANSIWDSVMRDKDMSSFMLPGSSHITDSEQRELPPEIPSHSANVKDTHSPDAPAASGTSESEALISHLDKQDTERETLQSDAASLATRLENPGYFPHPDPWKGHGDGQSESEKEAQGATDRGHLDEEEVIASGVENASGISEKGQSDQELSSLVASEHQEICIKSGKISSLAVTFSPQTEEPEEVLEYEEGSYNLDSRDVQTGMSADNLQPKDTHEKHLMSQRNSGETTETSDGMNFTKYVSVPEKDLEKTEECNFLEPENVGGGPPHRVPRSLDFGDVPIDSDVHVSSTCSEITKNLDVKGSENSLPGAGSSGNFDRDTISSEYTHSSASSPELNDSSVALSSWGQQPSSGYQEENQGNWSEQNHQESELITTDGQVEIVTKVKDLEKNRINEFEKSFDRKTPTFLEIWNDSVDGDSFSSLSSPETGKYSEHSGTHQESNLIASYQEKNEHDISATVQPEDARVISTSSGSDDDSVGGEESIEEEIQVANCHVAEDESRAWDSLNESNKFLVTADPKSENIYDYLDSSEPAENENKSNPFCDNQQSSPDPWTFSPLTETEMQITAVEKEKRSSPETGTTGDVAWQISPKASFPKNEDNSQLEMLGFSADSTEWWKASPQEGRLIESPFERELSDSSGVLEINSSVHQNASPWGVPVQGDIEPVETHYTNPFSDNHQSPFLEGNGKNSHEQLWNIQPRQPDPDADKFSQLVKLDQIKEKDSREQTFVSAAGDELTPETPTQEQCQDTMLPVCDHPDTAFTHAEENSCVTSNVSTNEGQETNQWEQEKSYLGEMTNSSIATENFPAVSSPTQLIMKPGSEWDGSTPSEDSRGTFVPDILHGNFQEGGQLASAAPDLWIDAKKPFSLKADGENPDILTHCEHDSNSQASDSPDICHDSEAKQETEKHLSACMGPEVESSELCLTEPEIDEEPIYEPGREFVPSNAELDSENATVLPPIGYQADIKGSSQPASHKGSPEPSEINGDNSTGLQVSEKGASPDMAPILEPVDRRIPRIENVATSIFVTHQEPTPEGDGSWISDSFSPESQPGARALFDGDPHLSTENPALVPDALLASDTCLDISEAAFDHSFSDASGLNTSTGTIDDMSKLTLSEGHPETPVDGDLGKQDICSSEASWGDFEYDVMGQNIDEDLLREPEHFLYGGDPPLEEDSLKQSLAPYTPPFDLSYLTEPAQSAETIEEAGSPEDESLGCRAAEIVLSALPDRRSEGNQAETKNRLPGSQLAVLHIREDPESVYLPVGAGSNILSPSNVDWEVETDNSDLPAGGDIGPPNGASKEISELEEEKTIPTKEPEQIKSEYKEERCTEKNEDRHALHMDYILVNREENSHSKPETCEERESIAELELYVGSKETGLQGTQLASFPDTCQPASLNERKGLSAEKMSSKSDTRSSFESPAQDQSWMFLGHSEVGDPSLDARDSGPGWSGKTVEPFSELGLGEGPQLQILEEMKPLESLALEEASGPVSQSQKSKSRGRAGPDAVTLQAVTHDNEWEMLSPQPVQKNMIPDTEMEEETEFLELGTRISRPNGLLSEDVGMDIPFEEGVLSPSAADMRPEPPNSLDLNDTHPRRIKLTAPNINLSLDQSEGSILSDDNLDSPDEIDINVDELDTPDEADSFEYTGHDPTANKDSGQESESIPEYTAEEEREDNRLWRTVVIGEQEQRIDMKVIEPYRRVISHGGYYGDGLNAIIVFAACFLPDSSRADYHYVMENLFLYVISTLELMVAEDYMIVYLNGATPRRRMPGLGWMKKCYQMIDRRLRKNLKSFIIVHPSWFIRTILAVTRPFISSKFSSKIKYVNSLSELSGLIPMDCIHIPESIIKLDEELREASEAAKTSCLYNDPEMSSMEKDIDLKLKEKP", "length": 3088 }, "evidence": [ { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99JU7-1", "protein_name": "Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein", "gene_name": "Bnipl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLGELELREEWQDEEFPRLLPEEPGSPGDPEDPQRGSQAGTPSSLALCGQRPMRKRLSAPEWQLSLTEGTGENGASPTRSASSSSAGSLDLEVDELETPSDSEQLDSGHEFEWEDDLPRAEGLGASEAAERLGRGCVCDVAGEDGHRWRVFRTGQREQRVDMTIIEPYKKVLSHGGYHGDGLNAVILFASCYLPRSSIPNYTYIMEHLFRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLRKNLRALVVVHATWYVKAFLALVRPFISSKFTRKIRFLDSLGELAQLISLEQVHIPEVVRQLDRDLHGSKGT", "length": 328 }, "evidence": [ { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VZJ4-1", "protein_name": "CRAL-TRIO domain-containing protein", "gene_name": "anon-EST:Posey64", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLHYAESESSPSESKMDISETPTDSTGVSPLADDVLPTAPEKNILKLEQAKQDHDKEELEFKTTSALDNRILRPELLPMEAMPQRHNIIERTLANSHPLMSPTNTDSDSEPFQLKKQEKQLPRSNFPDVVPTTETVQVKNNLNQCRNKPQDAKVSLLRANSPDILSSESDADVSQYLAAVESNFQSVSLMPNGNGKKSKRSTALPGGEDISSLDSISNHSFDDDEDIEHNLASLSPSSSLIDGLDGEDDDDDCEGPELLPDHDDDLELDLEFGLATTPTPNAPASATAASTLPQYTAAEERRDSRNWQKITLPDGRTREIDMRVIEPYKRVLSHGGYLKSGGQNAIVIFCACHLPDRSRADYSYVMDNLFLYVVKTLEQLVTDDYVLIYLHGGSNRRNVPPFPWLKRCYQLLDRRLRKSLKHMYLVHPTFWIKSLVWMARPFVSTKFWRKLVYVKSLEELGMHVVVEKAAIPEKVKQYDAKRH", "length": 484 }, "evidence": [ { "id": "HGNC:779", "url": "https://alliancegenome.org/gene/HGNC:779#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-185", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-185#orthology", "database": "AGR" }, { "id": "RGD:1309312", "url": "https://alliancegenome.org/gene/RGD:1309312#orthology", "database": "AGR" }, { "id": "MGI:2448730", "url": "https://alliancegenome.org/gene/MGI:2448730#orthology", "database": "AGR" }, { "id": "FB:FBgn0035488", "url": "https://alliancegenome.org/gene/FB:FBgn0035488#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4L2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4L2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4L2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4L2" } ], "pmid": "" }, { "name": "regulation of synaptic transmission, cholinergic", "id": "GO:0032222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032222", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4L2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4L2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P4L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4L2" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 169, "end_pos": 330, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P4Q2-1", "uniprot_ac": "A0A8M9P4Q2", "uniprot_id": "A0A8M9P4Q2_DANRE", "mass": { "chemical_mass": 34245.0, "monoisotopic_mass": 34245.0 }, "refseq": { "ac": "XP_021325257", "name": "LOW QUALITY PROTEIN: amine sulfotransferase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325257" }, "gene_names": [ { "name": "si:dkey-236e20.1", "type": "recommended", "evidence": [ { "id": "A0A8M9P4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2" } ] }, { "name": "si:dkey-236e20.1", "type": "synonym", "evidence": [ { "id": "XP_021325257", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325257" } ] } ], "protein_names": [ { "name": "Sulfotransferase", "type": "recommended", "evidence": [ { "id": "A0A8M9P4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2/entry#names_and_taxonomy" } ] }, { "name": "2.8.2.-", "type": "synonym", "evidence": [ { "id": "A0A8M9P4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2/entry#names_and_taxonomy" } ] }, { "name": "LOW QUALITY PROTEIN: amine sulfotransferase", "type": "synonym", "evidence": [ { "id": "XP_021325257", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325257" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 2 indels internal stop codons :: corrected 1 genomic stop codons ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021325257.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325257", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325257" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-236e20.1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-533", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-533", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "798316", "url": "https://www.ncbi.nlm.nih.gov/gene/798316", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:798316", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798316", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P4Q2", "url": "https://www.orthodb.org/?gene=A0A8M9P4Q2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11783", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11783", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00685", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325257", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325257", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P4Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-533", "url": "https://zfin.org/ZDB-GENE-060503-533", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAQEECKMLSDKLLNYKGTVLTVDIRHDITPEYIDSLQDFDARDDDVFVVAFPKSGNVFLQYMPHHMHRIMTLIXDFPEKAKQITYKQMPWIEYQEKGKDYSTRPLHSPRLFCSHLLEPLMPRALQKKGKVIYVMRNPKDVMVSYXSRSYDEMLKKFITGCMIGGSWFDHVKGWVTSKDKYNILILTYEEMIKDLRSVIVKICKFVGKNLSDAAIDKVVERATFNQMKVDPVANYESVPWKITDQPKGVFLRKGTVGDWRNSLTVAQSECLDRAFEERMKEVPNLVWDIAHFCG", "length": 294, "header": "tr|A0A8M9P4Q2-1|A0A8M9P4Q2_DANRE Isoform 1 of Sulfotransferase OS=Danio rerio OX=7955 GN=si:dkey-236e20.1 PE=3 SV=2 CANONICAL=A0A8M9P4Q2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P4Q2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2/entry#A0A8M9P4Q2-1", "sequence": { "sequence": "MAQEECKMLSDKLLNYKGTVLTVDIRHDITPEYIDSLQDFDARDDDVFVVAFPKSGNVFLQYMPHHMHRIMTLIXDFPEKAKQITYKQMPWIEYQEKGKDYSTRPLHSPRLFCSHLLEPLMPRALQKKGKVIYVMRNPKDVMVSYXSRSYDEMLKKFITGCMIGGSWFDHVKGWVTSKDKYNILILTYEEMIKDLRSVIVKICKFVGKNLSDAAIDKVVERATFNQMKVDPVANYESVPWKITDQPKGVFLRKGTVGDWRNSLTVAQSECLDRAFEERMKEVPNLVWDIAHFCG", "length": 294, "header": "tr|A0A8M9P4Q2-1|A0A8M9P4Q2_DANRE Isoform 1 of Sulfotransferase OS=Danio rerio OX=7955 GN=si:dkey-236e20.1 PE=3 SV=2 CANONICAL=A0A8M9P4Q2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "dre:798316", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798316", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KF40-1", "protein_name": "2.8.2.-", "gene_name": "St3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNRVQVTPRSYPTNLIDKDWGNRKLFYTKDSENFLRLVHDMKLRDDDVWIVTLPKCGTTWMQELLWLLLNNCDFEGALAKDQELRTPFLEFGYSVFHDPNRSFGPIEDLKSPRLIKSHLSLALLPSKLWEGKNKVIYVSRNPLDSYVSRYYHGVSFGFNYGKSLHQYFDEVLASDDFPTEFIEHAHEFYQLRNEPWVFYTSFEMMKKDLRGVINDVSRFLNKPINDQQMEKLLKHLSFAEMKKNPTTNHLWELAQVQHENAGKEMHPFVRRGDVNGYKDELKPEQIEKANVRIQEVLAKNGVTLDELLLLKDQDWPCSGLCTQHSQTNSEAITLRNGPKAHQHQCSSACTRWLCVRVKVVKAESRGRTGPILMLMQGSRDAEMPTPPPQREAKNGKQATFIAGREVFTVLWERRISQDVNRGSCTMFAPHSLPVTSRLLLLVVTLLFCPVQAHLSKRSYSDQSVHGYMTERTCWWNEVCKEEFQSLFRCKCPQFSYCRSPGRYYNAYCSMTDTGYIWTQPNWDWGA", "length": 526 }, "evidence": [ { "id": "MGI:1931469", "url": "https://alliancegenome.org/gene/MGI:1931469#orthology", "database": "AGR" }, { "id": "MGI:3645972", "url": "https://alliancegenome.org/gene/MGI:3645972#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "G5E904-1", "protein_name": "Sulfotransferase", "gene_name": "Sult3a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNKDEDIFKFKGYNFLRALVSMDIVKNMEDYEIRDDDIFIVTYPKSGTTWTQQILCLICFESHRNGTENIATIDRIPSFEYNIHKLDYAKMPSPRIFTSHIPYYLVPKGLKDKKAKIIYVYRNPKDVLISFFHFSNLMVVLKASDTLENFMQRFLNGNLVGSLWFDHIRGWYEHRHDFNIMFMSFEDMKKDLRSSVLKICSFLEKELSEEDMDAVVRQATFEKMKADPRANNEHIIKDELGTRNNTGAFLRKGIVGDWKHYLTVDQSERFDKIFHMNMKNIPLKFIWNINEK", "length": 293 }, "evidence": [ { "id": "MGI:3645972", "url": "https://alliancegenome.org/gene/MGI:3645972#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-533", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-533#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O35403-1", "protein_name": "Amine sulfotransferase", "gene_name": "Sult3a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNKDEYLLNFKGYNFQKTLVKMEVVENIENYEIRDDDIFIVTYPKSGTIWTQQILSLIYFEGHRNRTENIETIDRAPFFEYNIHKLDYAKMPSPRIFSSHIPYYLVPKGLKDKKAKILYMYRNPKDVLISYFHFSNLMLIFQNPDTVESFMQTFLDGDVVGSLWFDHIRGWYEHRHDFNIMFMSFEDMKKDFRSSVLKICSFLEKELSEEDVDAVVRQATFQKMKADPRANYEHIIKDELGTRNEMGSFLRKGVVGAWKHYLTVDQSERFDKIFHRNMKNIPLKFIWDINEE", "length": 293 }, "evidence": [ { "id": "MGI:1931469", "url": "https://alliancegenome.org/gene/MGI:1931469#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-533", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-533#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1L873-1", "protein_name": "Sulfotransferase", "gene_name": "sult3st5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQEECKMISDKLLKYKGTVLTLEPSYDITPEYIDSIQDFETRDDDVFVVTFPKSGTVWTQRIITLIYEEDFPEKAKQITFEQMPWIEYREKGKDYSTRPSPRLFCSHLLEPLMPKTLKRKGKVIYVMRNPKDVMVSYFHFSQKMKDLDSAKSYDEVLENFLTGCMVGGSWFDHVKGWVTSKDKYNILILTYEEMIKDLRSVIVKICKFVGKNLSDAAIDKVVERATFKQMKVDPVANYESLPVDIIDQPKGAFMRKGTVGDWRNSLTVAQSECVDRALEERMKDVPLNLVWDITELRG", "length": 299 }, "evidence": [ { "id": "MGI:1931469", "url": "https://alliancegenome.org/gene/MGI:1931469#orthology", "database": "AGR" }, { "id": "MGI:3645972", "url": "https://alliancegenome.org/gene/MGI:3645972#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1L875-1", "protein_name": "Sulfotransferase", "gene_name": "sult3st2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQEECKMISDKLLKYKGTVLTMETNHDITPEYIDSLQDFETRDDDVFVVTFPKSGTVWTQRIMTLIYEEDFPEKANEITYEQMPWIEYREKGKDYNARPSPRLFCSHLLEPLMPRALQKKGKVIYVMRNPKDVMVSYFHFSNKMKNLDSSENYDEILENFFTGCMIGGSWFDHVKGWVTSKDKYNILILTYEEMIKDLRSVIVKICKFVGKNLSDAAINKVVERTTFNQMKVDPVANYESLPQEVTDQPKGVFMRKGTVGDWKNSLTVAQSECVDRVFEERMKHVPLNLVWDIAELRG", "length": 299 }, "evidence": [ { "id": "MGI:1931469", "url": "https://alliancegenome.org/gene/MGI:1931469#orthology", "database": "AGR" }, { "id": "MGI:3645972", "url": "https://alliancegenome.org/gene/MGI:3645972#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9W1L8-1", "protein_name": "2.8.2.-", "gene_name": "St1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPQSSFFAKSVPFEQIDKLAISGGYSSIFASSKPSVPVVGNWEQRFCRLADTFQPVLDRVYDFEVRDDDVWIVTLPKCGTTWMQELAWLVINECDFETAKSVDLTHRSPFLEFNGVVPNVPHDTIAAANALPSPRLIKSHLPAWMLPRQIWSKRPKIIYVYRNPKDAAISYFHHWRGMVGYQGTKSDFMHSFIDGYVNFTPCWPHILDFWQLRHEPNIFFTSYERMKGQLGQVISEVAQFLERSVSQEQMQQMQRHLSFESMRDNPACNHVKEFESMKAAAGREVEEFRFVRRGVVGSHKDELTADIIREFDLWSDSNLRDFKLNMDDFANYSKFAST", "length": 338 }, "evidence": [ { "id": "MGI:1931469", "url": "https://alliancegenome.org/gene/MGI:1931469#orthology", "database": "AGR" }, { "id": "MGI:3645972", "url": "https://alliancegenome.org/gene/MGI:3645972#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "sulfotransferase activity", "id": "GO:0008146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008146", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sulfation", "id": "GO:0051923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051923", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2" } ], "pmid": "" }, { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2" } ], "pmid": "" }, { "name": "catecholamine metabolic process", "id": "GO:0006584", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006584", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P4Q2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P4Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P4Q2" }, { "id": "PF00685", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00685" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfotransferase", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 282, "start_aa": "Asp", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325532.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325532" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P584", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P584" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch1073-228j22.2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P584", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110411-227", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-227", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P584", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P584", "database": "AlphaFoldDB", "categories": [] }, { "id": "100334514", "url": 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Pathway" ] }, { "id": "A0A8M9P584", "url": "https://www.orthodb.org/?gene=A0A8M9P584", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12245:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12245:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325532", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325532", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P584", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P584", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P584-1", "url": 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"MRDQQTDGADSARALTEVDHLVRFLRSDWMGLTLCCWLRDGLPKNPNQSSSAFTPFSVTPPIRLAVLLDTPPVAPGNPRSQWSPTHLSPNLQRCVSGVRVHRGHVEQSSDAARAAVGTSTGLHIWEVKWEGQQRGSHALLGVSTHKSPLQASGYKALIGGDSCSWGWELSTNQLWHDGKEGRSYPGGGATGVLSVPDCVLLVVDADAGTLGYVVDDCYLGVAFQDLPKGVELFPAVSCVWGGAEICIRYLSGTTRDAPALQALSRLSARRALRLHGTQNHTHSLPSALQRLLLDTHTHHRDTPEHAQTQMLLVT", "length": 314, "header": "tr|A0A8M9P584-1|A0A8M9P584_DANRE Isoform 1 of SPRY domain-containing SOCS box protein 2 OS=Danio rerio OX=7955 GN=si:ch1073-228j22.2 PE=3 SV=3 CANONICAL=A0A8M9P584-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100334514", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100334514", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O88838-1", "protein_name": "SPRY domain-containing SOCS box protein 2", "gene_name": "Spsb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P584", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P584" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P584", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P584" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P584", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P584" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": 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"https://www.ncbi.nlm.nih.gov/protein/XP_073779873" }, "gene_names": [ { "name": "LOC110438326", "type": "recommended", "evidence": [ { "id": "A0A8M9P5L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5L6" } ] }, { "name": "LOC110438326", "type": "synonym", "evidence": [ { "id": "XP_073779873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073779873" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9P5L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5L6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_073779873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073779873" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073779873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073779873" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P5L6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5L6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438326", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5L6", "locus": {} } ], "crossref": [ { "id": "A0A8M9P5L6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P5L6", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438326", "url": "https://www.ncbi.nlm.nih.gov/gene/110438326", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:110438326", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438326", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P5L6", "url": "https://www.orthodb.org/?gene=A0A8M9P5L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31025", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31025", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31025:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31025:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_073779873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073779873", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P5L6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P5L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5L6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAATDKYTPKLLKLYRARKGAFGHEMEELLERLDERTTEIVNHRRTSALEGLPLFLREKQTNLFKKCKETEDRTKGVSVGILYVTEDDYRAASPVIQNIAVVLEEVVVLEDIPDTSSAVAYLFGLLHALNFSYPKELRYTFDTIQIVFMELGTGCTQR", "length": 158, "header": "tr|A0A8M9P5L6-1|A0A8M9P5L6_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC110438326 PE=4 SV=2 CANONICAL=A0A8M9P5L6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P5L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5L6/entry#A0A8M9P5L6-1", "sequence": { "sequence": "MAATDKYTPKLLKLYRARKGAFGHEMEELLERLDERTTEIVNHRRTSALEGLPLFLREKQTNLFKKCKETEDRTKGVSVGILYVTEDDYRAASPVIQNIAVVLEEVVVLEDIPDTSSAVAYLFGLLHALNFSYPKELRYTFDTIQIVFMELGTGCTQR", "length": 158, "header": "tr|A0A8M9P5L6-1|A0A8M9P5L6_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC110438326 PE=4 SV=2 CANONICAL=A0A8M9P5L6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110438326", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438326", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PG37-1", "uniprot_ac": "A0A8M9PG37", "uniprot_id": "A0A8M9PG37_DANRE", "mass": { "chemical_mass": 73761.0, "monoisotopic_mass": 73761.0 }, "refseq": { "ac": "XP_021325878", "name": "potassium voltage-gated channel subfamily C member 3b isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325878" }, "gene_names": [ { "name": "kcnc3b", "type": "recommended", "evidence": [ { "id": "A0A8M9PG37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37" } ] }, { "name": "kcnc3b", "type": "synonym", "evidence": [ { "id": "XP_021325878", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325878" } ] } ], "protein_names": [ { "name": "Potassium voltage-gated channel subfamily C member 3b isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PG37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37/entry#names_and_taxonomy" } ] }, { "name": "potassium voltage-gated channel subfamily C member 3b isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325878", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325878" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325878", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325878" } ] } ], "disease": [ { "disease_id": "DOID:0050963", "recommended_name": { "id": "DOID:0050963", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050963", "name": "spinocerebellar ataxia 13", "description": "An autosomal dominant cerebellar ataxia that is characterized by developmental delay, ataxia, myoclinic jerks, dysarthria, dysphagia and seizure, and has_material_basis_in mutation in the KCNC3 gene." }, "synonyms": [ { "id": "MONDO:0011529", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011529", "name": "spinocerebellar ataxia type 13", "description": "Spinocerebellar ataxia type 13 (SCA13) is a very rare subtype of type I autosomal dominant cerebellar ataxia (ADCA type I). It is characterized by onset in childhood marked by delayed motor and cognitive development followed by mild progression of cerebellar ataxia." }, { "id": "MONDO:0011529", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011529", "name": "SCA13", "description": "" }, { "id": "MONDO:0011529", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011529", "name": "spinocerebellar ataxia type 13", "description": "" }, { "id": "MONDO:0011529", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011529", "name": "autosomal dominant cerebellar ataxia with intellectual disability", "description": "" }, { "id": "MONDO:0011529", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011529", "name": "autosomal dominant cerebellar ataxia with mental retardation", "description": "" }, { "id": "MONDO:0011529", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011529", "name": "cerebellar ataxia, autosomal dominant with intellectual disability", "description": "" }, { "id": "MONDO:0011529", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011529", "name": "cerebellar ataxia, autosomal dominant with mental retardation", "description": "" }, { "id": "MONDO:0011529", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011529", "name": "spinocerebellar ataxia 13", "description": "" }, { "id": "MIM:605259", "resource": "MIM", "url": "https://www.omim.org/entry/605259", "name": "Spinocerebellar ataxia 13", "description": "Spinocerebellar ataxia 13" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050963", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050963" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "kcnc3b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100901-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100901-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PG37", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PG37", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18414", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18414", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "564371", "url": "https://www.ncbi.nlm.nih.gov/gene/564371", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003131", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003131", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003968", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003968", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003974", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003974", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564371", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564371", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PG37", "url": "https://www.orthodb.org/?gene=A0A8M9PG37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11537:SF277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11537:SF277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02214", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02214", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325878", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325878", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P5Y6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5Y6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P5Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5Y6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PG37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PG37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PG40", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PG40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLW2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PU62", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PU62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PU62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PU62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IQT0", "url": "https://www.uniprot.org/uniprotkb/A0AC58IQT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IQT0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IQT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IQU4", "url": "https://www.uniprot.org/uniprotkb/A0AC58IQU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IQU4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IQU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IQV0", "url": "https://www.uniprot.org/uniprotkb/A0AC58IQV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IQV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IQV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100901-2", "url": "https://zfin.org/ZDB-GENE-100901-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLSSVCVSSFKGRKGGNKSSNKACYSADMTCPSESEKIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPEVPDDDPALAGDGDLKRLCLQEDGRKAGWWRVWRPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNTIYNKTENVTEGNVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKMEFFKSPLNIIDFVAVLPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRAPQPGSPNYCKPDALAMATASPQRILGNVLGGVLGSSGLTGDCPLAQEEIIEINRDSKQNGDAASAALANEDCPTIDQVLSPDERSPVGRTQERYQQDRACFLLNTREFRPTDGNVRKGCVISRVCMLASSYILSLFYCLPRPPPPPRSARECVCVCVCCVCCDVTSLIVFSMCFPSLYR", "length": 658, "header": "tr|A0A8M9PG37-1|A0A8M9PG37_DANRE Isoform 1 of Potassium voltage-gated channel subfamily C member 3b isoform X1 OS=Danio rerio OX=7955 GN=kcnc3b PE=4 SV=1 CANONICAL=A0A8M9PG37-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P5Y6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37/entry#A0A8M9P5Y6-1", "sequence": { "sequence": "MLSSVCVSSFKGRKGGNKSSNKACYSADMTCPSESEKIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPEVPDDDPALAGDGDLKRLCLQEDGRKAGWWRVWRPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNTIYNKTENVTEGNVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKMEFFKSPLNIIDFVAVLPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRAPQPGSPNYCKPDALAMATASPQRILGNVLGGVLGSSGLTGDCPLAQEEIIEINRDSKQNGDAASAALANEDCPTIDQVLSPDERSPVGRTQERYQQDRACFLLNTREFRPTDGNVRKGRQCSARVSNA", "length": 607, "header": "tr|A0A8M9P5Y6-1|A0A8M9PG37_DANRE Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 3b isoform X1 OS=Danio rerio OX=7955 GN=kcnc3b PE=4 SV=1 CANONICAL=A0A8M9PG37-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PG37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37/entry#A0A8M9PG37-1", "sequence": { "sequence": "MLSSVCVSSFKGRKGGNKSSNKACYSADMTCPSESEKIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPEVPDDDPALAGDGDLKRLCLQEDGRKAGWWRVWRPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNTIYNKTENVTEGNVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKMEFFKSPLNIIDFVAVLPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRAPQPGSPNYCKPDALAMATASPQRILGNVLGGVLGSSGLTGDCPLAQEEIIEINRDSKQNGDAASAALANEDCPTIDQVLSPDERSPVGRTQERYQQDRACFLLNTREFRPTDGNVRKGCVISRVCMLASSYILSLFYCLPRPPPPPRSARECVCVCVCCVCCDVTSLIVFSMCFPSLYR", "length": 658, "header": "tr|A0A8M9PG37-1|A0A8M9PG37_DANRE Isoform 1 of Potassium voltage-gated channel subfamily C member 3b isoform X1 OS=Danio rerio OX=7955 GN=kcnc3b PE=4 SV=1 CANONICAL=A0A8M9PG37-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PG40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37/entry#A0A8M9PG40-1", "sequence": { "sequence": "MLSSVCVSSFKGRKGGNKSSNKACYSADMTCPSESEKIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPEVPDDDPALAGDGDLKRLCLQEDGRKAGWWRVWRPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNTIYNKTENVTEGNVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKMEFFKSPLNIIDFVAVLPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRAPQPGSPNYCKPDALAMATASPQRILGNVLGGVLGSSGLTGDCPLAQEEIIEINRDSKQNGDAASAALANEDCPTIDQVLSPDERSPVGRTQERYQQDRACFLLNTREFRPTDGNVRKVLSF", "length": 600, "header": "tr|A0A8M9PG40-1|A0A8M9PG40_DANRE Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 3b isoform X6 OS=Danio rerio OX=7955 GN=kcnc3b PE=4 SV=1 CANONICAL=A0A8M9PG37-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PLW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37/entry#A0A8M9PLW2-1", "sequence": { "sequence": "MLSSVCVSSFKGRKGGNKSSNKACYSADMTCPSESEKIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPEVPDDDPALAGDGDLKRLCLQEDGRKAGWWRVWRPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNTIYNKTENVTEGNVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKMEFFKSPLNIIDFVAVLPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRAPQPGSPNYCKPDALAMATASPQRILGNVLGGVLGSSGLTGDCPLAQEEIIEINRDSKQNGDAASAALANEDCPTIDQVLSPDERSPVGRTQERYQQDRACFLLNTREFRPTDGNVRKGCVISRVSTGYEKSRSLNNISGMAGSSLRLTPITSTPFDPYEAPGPLRRCRSPIPSIL", "length": 654, "header": "tr|A0A8M9PLW2-1|A0A8M9PLW2_DANRE Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 3b isoform X2 OS=Danio rerio OX=7955 GN=kcnc3b PE=4 SV=1 CANONICAL=A0A8M9PG37-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PU62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37/entry#A0A8M9PU62-1", "sequence": { "sequence": "MLSSVCVSSFKGRKGGNKSSNKACYSADMTCPSESEKIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPEVPDDDPALAGDGDLKRLCLQEDGRKAGWWRVWRPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNTIYNKTENVTEGNVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKMEFFKSPLNIIDFVAVLPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRAPQPGSPNYCKPDALAMATASPQRILGNVLGGVLGSSGLTGDCPLAQEEIIEINRDSKQNGDAASAALANEDCPTIDQVLSPDERSPVGRTQERYQQDRACFLLNTREFRPTDGNVRKGCVISRVCRQCSARVSNA", "length": 614, "header": "tr|A0A8M9PU62-1|A0A8M9PG37_DANRE Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 3b isoform X1 OS=Danio rerio OX=7955 GN=kcnc3b PE=4 SV=1 CANONICAL=A0A8M9PG37-1" }, "locus": {} }, { "isoform_ac": "A0AC58IQT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37/entry#A0AC58IQT0-1", "sequence": { "sequence": "MTCPSESEKIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPEVPDDDPALAGDGDLKRLCLQEDGRKAGWWRVWRPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNTIYNKTENVTEGNVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKMEFFKSPLNIIDFVAVLPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRAPQPGSPNYCKPDALAMATASPQRILGNVLGGVLGSSGLTGDCPLAQEEIIEINRDSKQNGDAASAALANEDCPTIDQVLSPDERSPVGRTQERYQQDRACFLLNTREFRPTDGNVRKGCVISRVCRQCSARVSNA", "length": 586, "header": "tr|A0AC58IQT0-1|A0AC58IQT0_DANRE Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 3b isoform X7 OS=Danio rerio OX=7955 GN=kcnc3b PE=4 SV=1 CANONICAL=A0A8M9PG37-1" }, "locus": {} }, { "isoform_ac": "A0AC58IQU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37/entry#A0AC58IQU4-1", "sequence": { "sequence": "MTCPSESEKIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPEVPDDDPALAGDGDLKRLCLQEDGRKAGWWRVWRPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNTIYNKTENVTEGNVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKMEFFKSPLNIIDFVAVLPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRAPQPGSPNYCKPDALAMATASPQRILGNVLGGVLGSSGLTGDCPLAQEEIIEINRDSKQNGDAASAALANEDCPTIDQVLSPDERSPVGRTQERYQQDRACFLLNTREFRPTDGNVRKVLSF", "length": 572, "header": "tr|A0AC58IQU4-1|A0AC58IQU4_DANRE Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 3b isoform X9 OS=Danio rerio OX=7955 GN=kcnc3b PE=4 SV=1 CANONICAL=A0A8M9PG37-1" }, "locus": {} }, { "isoform_ac": "A0AC58IQV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37/entry#A0AC58IQV0-1", "sequence": { "sequence": "MTCPSESEKIVINCGGVRHETYRSTLKTLPGTRLSWLTEPDAFSNFDYDPKSDEFFFDRHPSVFSFILNYYRTGKLHCPNDVCGPLFEEELAFWGIDETDVEACCWMNYRQHRDAEEALDSFETPEPEVPDDDPALAGDGDLKRLCLQEDGRKAGWWRVWRPRIWALFEDPYSSKYARYVAFGSLLFILISISTFCMETHEAFNTIYNKTENVTEGNVTREEIVYEVVTDSWLTYVEGVCVVWFTIEVFTRVVFCPDKMEFFKSPLNIIDFVAVLPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGASPDDPTASAHTNFKNIPIGFWWAVVTMTTLGYGDMYPETWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRAPQPGSPNYCKPDALAMATASPQRILGNVLGGVLGSSGLTGDCPLAQEEIIEINRDSKQNGDAASAALANEDCPTIDQVLSPDERSPVGRTQERYQQDRACFLLNTREFRPTDGNVRKGRQCSARVSNA", "length": 579, "header": "tr|A0AC58IQV0-1|A0AC58IQV0_DANRE Computationally mapped isoform of Potassium voltage-gated channel subfamily C member 3b isoform X8 OS=Danio rerio OX=7955 GN=kcnc3b PE=4 SV=1 CANONICAL=A0A8M9PG37-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:564371", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564371", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PUH5-1", "protein_name": "Voltage-gated potassium channel KCNC4-like", "gene_name": "si:ch73-334d15.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSLGVCSLEASEGSSEKIVLNVGGVKHETLRTTLMSLPGSRLAELVNTEKSPSELFFDRHPEVFAHVLQYYRSGKLHCPSNLCGLLLEEEFTFWGISSADVEPCCWETFQQNKETLKALAGIKPSVMKKEEESGQKQQSSSSRGWQRKIWALFDKPYSSVCARIIAIISLFFILLSIIAFSLWTLPSINSHQFLNAWASNSTDDFSRTRPPEAQALDAVEIVCSIWFVFEFAIRAGSCPSKLWFFINVMNIVDLLALFPWFFRWSSNNFSVFALGFLHAMRCIRLLRVFKLMQHVFGVRVLTHTLRASLTSLCIVPLLLSICTLIFGTMFYFAELTHKDSYISSSSGLDGFWWALVTLTTVGYGDMLPVTRQGKCVAFLCAMVGVLLIVLPVPIIVNNFLKFSSLVKTKHSMPRMNEKRSVDVGPSYST", "length": 430 }, "evidence": [ { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A8DYR5-1", "protein_name": "Shaw-like, isoform C", "gene_name": "Shawl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDGENRIILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFTQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENEKPTEEQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQPHEAFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTDVMQRMGEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFYSHTQARSKLPKKRRRVLPVEQPRRKREPTAPHRGRTNAIKQTPPTGPGLVAGGVVPVGAGGPGLGGHAVGHSAAGAPMFKDAFGGAKIGTVNVNGVNVIGLHPAQRTTTTMAMAMNEADPTPMSALTYQVPMLQPTPTPAHSHGHAHGHAHGLGPASAAMTSSASLTGSAASAAVATAAAAAPAGPSFISSDYLSVPAVQSLQPRAATTGHDFMLPLQPKLLGPLERKDQHPLQLTAHNLASDTHQLMYSGHAHSQHKVGGGAAVLNVPPTLSMSHTQMPPGIASMGQRTPNLSFRPAHGASSQVATVQQPIPHSHACHASTNCNIKISVASAGLSVGCPDEFRTPKVTLLDDLSDDVNSSTDDCGDCCLVDDSDTYEGTTINNGPSGQENGTEAIGLDDGLLDNDGEDEEDGEGSGVGGDSGDSLGGIYIGPRH", "length": 937 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100901-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100901-2#orthology", "database": "AGR" }, { "id": "MGI:96669", "url": "https://alliancegenome.org/gene/MGI:96669#orthology", "database": "AGR" }, { "id": "RGD:621358", "url": "https://alliancegenome.org/gene/RGD:621358#orthology", "database": "AGR" }, { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F1Q4T7-1", "protein_name": "Potassium voltage-gated channel subfamily C member 1b isoform X1", "gene_name": "kcnc1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGQGDDKDRIVINVGGIKHQTYRSTLRTLPGTRLSWLAEPDAPNNFDYDANIGEFFFDRHPSVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHREAEEALDSFTGGALDLGHDDPEPEGVVEAAEGDEGVEMTRRLAQGDSPDNRSGRWSRWQKKAWALFEDPYSSKYARWVAFASLFFILVSITTFCLETHEAFNPIINRTETYMEGNETVERIFPETETMVQLTYIEGVCVVWFTFEFIIRVTTCPDKLKFLRNTLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFILLIIFLALGVLIFATMIYYAERIGRNPNDPDASSDTHFKNIPIGFWWAVVTMTTLGYGDMYPQTTSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIRRPPLLGSPNYCRSAVNSPRPSTHSDTCPLAQEEVSEIRYPDFKVNGEPSKAALANEDCPHIDQAVSPEEVFSPVDRERPCFLLTGGERANHTGGRVRKGYEKPWSHSSMSGGVASVSALPCSPPCLMQQVHSPIPSIL", "length": 598 }, "evidence": [ { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P15388-1", "protein_name": "Voltage-gated potassium channel KCNC1", "gene_name": "Kcnc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAGRKPLRGMSI", "length": 511 }, "evidence": [ { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P17972-1", "protein_name": "Potassium voltage-gated channel protein Shaw", "gene_name": "Shaw", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNLINMDSENRVVLNVGGIRHETYKATLKKIPATRLSRLTEALANYDPILNEYFFDRHPGVFAQVLNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWMTYTQHRDTQETLAVLDRLDLDTEKPSEEELARKFGFEEDYYKGTISWWQEMKPRIWSLFDEPYSSNAAKTIGVVSVFFICISILSFCLKTHPDMRVPIVRNITVKTANGSNGWFLDKTQTNAHIAFFYIECVCNAWFTFEILVRFISSPNKWEFIKSSVNIIDYIATLSFYIDLVLQRFASHLENADILEFFSIIRIMRLFKLTRHSSGLKILIQTFRASAKELTLLVFFLVLGIVIFASLVYYAERIQPNPHNDFNSIPLGLWWALVTMTTVGYGDMAPKTYIGMFVGALCALAGVLTIALPVPVIVSNFAMYYSHTQARAKLPKKRRRVLPVEQPRQPRLPGAPGGVSGCGTPGSGPHSGPMGSGGTGPRRMNNKTKDLVSPKSDMAFSFD", "length": 498 }, "evidence": [ { "id": "HGNC:6235", "url": "https://alliancegenome.org/gene/HGNC:6235#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100901-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100901-2#orthology", "database": "AGR" }, { "id": "MGI:96669", "url": "https://alliancegenome.org/gene/MGI:96669#orthology", "database": "AGR" }, { "id": "RGD:621358", "url": "https://alliancegenome.org/gene/RGD:621358#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P22462-1", "protein_name": "Voltage-gated potassium channel KCNC2", "gene_name": "Kcnc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKIENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQGDCLTAAGDKLQPLPPPLSPPPRPPPLSPVPSGCFEGGAGNCSSHGGNGSDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLGGKRLGIEDAAGLGGPDGKSGRWRKLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSAVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPLASSPTFCKTELNMACNSTQSDTCLGKENRLLEHNRSVLSGDDSTGSEPPLSPPERLPIRRSSTRDKNRRGETCFLLTTGDYTCASDGGIRKGYEKSRSLNNIAGLAGNALRLSPVTSPYNSPCPLRRSRSPIPSIL", "length": 638 }, "evidence": [ { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P25122-1", "protein_name": "Voltage-gated potassium channel KCNC1", "gene_name": "Kcnc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVVFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRADSKLNGEVAKAALANEDCPHIDQALTPDEGLPFTRSGTRERYGPCFLLSTGEYACPPGGGMRKDLCKESPVIAKYMPTEAVRVT", "length": 585 }, "evidence": [ { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P48547-1", "protein_name": "Voltage-gated potassium channel KCNC1", "gene_name": "KCNC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQGDESERIVINVGGTRHQTYRSTLRTLPGTRLAWLAEPDAHSHFDYDPRADEFFFDRHPGVFAHILNYYRTGKLHCPADVCGPLYEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDSFGGAPLDNSADDADADGPGDSGDGEDELEMTKRLALSDSPDGRPGGFWRRWQPRIWALFEDPYSSRYARYVAFASLFFILVSITTFCLETHERFNPIVNKTEIENVRNGTQVRYYREAETEAFLTYIEGVCVVWFTFEFLMRVIFCPNKVEFIKNSLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKKKHIPRPPQLGSPNYCKSVVNSPHHSTQSDTCPLAQEEILEINRAGRKPLRGMSI", "length": 511 }, "evidence": [ { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q01956-1", "protein_name": "Voltage-gated potassium channel KCNC3", "gene_name": "Kcnc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSSVCVWSFSGRQGTRKQHSQPAPTPQPPESSPPPLLPPPQQQCAQPGTAASPAGAPLSCGPGGRRAEPCSGLPAVAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGTDEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDSSGNANANAGGAHDAGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPAGGPGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRVTFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPPGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEEVIETNRAGNDLGVLEEGDPRPNGDPAAAALAHEDCPAIDQPAMSPEDKSPITPGSRGRYSRDRACFLVTDYAPSPDGSIRKATGAPPLPPHAGVSQAPPASCPTSTPTQQPGYPPSGRAPSPPQATPEAPAIFDVWLPPFHRSHQPPGKHQRGGRHPGVSPSPQQRACVGEPPSASHPQSLTLCISVPSSCHRLRPRETLGFPLSLPPRLATGNGGRECPRDPGLPFPSRHSSPAV", "length": 889 }, "evidence": [ { "id": "HGNC:6235", "url": "https://alliancegenome.org/gene/HGNC:6235#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100901-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100901-2#orthology", "database": "AGR" }, { "id": "MGI:96669", "url": "https://alliancegenome.org/gene/MGI:96669#orthology", "database": "AGR" }, { "id": "RGD:621358", "url": "https://alliancegenome.org/gene/RGD:621358#orthology", "database": "AGR" }, { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q03721-1", "protein_name": "Voltage-gated potassium channel KCNC4", "gene_name": "KCNC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPETDGGGVGSSGSSGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGSGAGPSDEAGDDERELALQRLGPHEGGAGHGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEILRVGNITSVHFRREVETEPILTYIEGVCVLWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPAQLESPMYCKSEETSPRDSTCSDTSPPAREEGMIERKRADSKQNGDANAVLSDEEGAGLTQPLASSPTPEERRALRRSTTRDRNKKAAACFLLSTGDYACADGSVRKGTFVLRDLPLQHSPEAACPPTAGTLFLPH", "length": 635 }, "evidence": [ { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q14003-1", "protein_name": "Voltage-gated potassium channel KCNC3", "gene_name": "KCNC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSSVCVSSFRGRQGASKQQPAPPPQPPESPPPPPLPPQQQQPAQPGPAASPAGPPAPRGPGDRRAEPCPGLPAAAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGADEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDPAGAANAANAAGAHDGGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPPGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVTVAGAYPAGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEEVIEINRADPRPNGDPAAAALAHEDCPAIDQPAMSPEDKSPITPGSRGRYSRDRACFLLTDYAPSPDGSIRKATGAPPLPPQDWRKPGPPSFLPDLNANAAAWISP", "length": 757 }, "evidence": [ { "id": "HGNC:6235", "url": "https://alliancegenome.org/gene/HGNC:6235#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100901-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100901-2#orthology", "database": "AGR" }, { "id": "MGI:96669", "url": "https://alliancegenome.org/gene/MGI:96669#orthology", "database": "AGR" }, { "id": "RGD:621358", "url": "https://alliancegenome.org/gene/RGD:621358#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q14B80-1", "protein_name": "Voltage-gated potassium channel KCNC2", "gene_name": "Kcnc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKIESNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPQGDCLTAAGDKLQPLPPPLSPPPRPPPLSPVPSGCFEGGAGNCSSHGGNGGNGGSDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRKLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSPVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPLASSPTFCKTELNMACNSTQSDTCLGKENRLLEHNRSVLSGDDSTGSEPPLSPPERLPIRRSSTRDKNRRGETCFLLTTGDYTCASDGGIRKGYEKSRSLNNIAGLAGNALRLSPVTSPYNSPCPLRRSRSPIPSIL", "length": 642 }, "evidence": [ { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63734-1", "protein_name": "Voltage-gated potassium channel KCNC4", "gene_name": "Kcnc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPESDGGGAGSSGSSGGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGGGAGPGDEAGDDERELALQRLGPHEGGSGPGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEIHRVGNITSVRFRREVETEPILTYIEGVCVMWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPPQLESPIYCKSEETSPRDSTYSDTSPPAREEGMVERKRADSKQNGDANAVLSDEEGAGLTQPLASAPTPEERRALRRSGTRDRNKKAAACFLLSAGDYACADGSVQKEGSVEPKACVPVSHTCAL", "length": 625 }, "evidence": [ { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63959-1", "protein_name": "Voltage-gated potassium channel KCNC3", "gene_name": "Kcnc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSVCVWSFRGRQGTGKQQPQPVPTPQPPESSPPPLPPPQQQQCSQPGTAASPAGAPLSCGPGGRRAEPCPGLPAVAMGRHGGGGGDSGKIVINVGGVRHETYRSTLRTLPGTRLAGLTEPEAAARFDYDPGTDEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELGFWGIDETDVEACCWMTYRQHRDAEEALDSFEAPDSSANANANAGGAHDAGLDDEAGAGGGGLDGAGGELKRLCFQDAGGGAGGPAGGAGGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGFIHISNKTVTQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRVTFCPDKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNHTYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKNKHIPRPPQPGSPNYCKPDPPPPPPPHPHHGSGGISPPPPITPPSMGVNVAGAYPPGPHTHPGLLRGGAGGLGIMGLPPLPAPGEPCPLAQEEVIETNRADPRPNGDPAAAALAHEDCPAIDQPAMSPEDKSPITPGSRGRYSRDRACFLVTDYAPSPDGSIRKGYEKSRSLSSIVGLSGVSLRLAPLATPPGSPRATRRAPPTLPSIL", "length": 769 }, "evidence": [ { "id": "HGNC:6235", "url": "https://alliancegenome.org/gene/HGNC:6235#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100901-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100901-2#orthology", "database": "AGR" }, { "id": "MGI:96669", "url": "https://alliancegenome.org/gene/MGI:96669#orthology", "database": "AGR" }, { "id": "RGD:621358", "url": "https://alliancegenome.org/gene/RGD:621358#orthology", "database": "AGR" }, { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R1C0-1", "protein_name": "Voltage-gated potassium channel KCNC4", "gene_name": "Kcnc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MISSVCVSSYRGRKSGNKPPSKTCLKEEMAKGEASEKIIINVGGTRHETYRSTLRTLPGTRLAWLADPDGGGRPESDGGGAGSSGSSGGGGGGGGCEFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELTFWGIDETDVEPCCWMTYRQHRDAEEALDIFESPDGGGGGAGPGDEAGDDERELALQRLGPHEGGSGPGAGSGGCRGWQPRMWALFEDPYSSRAARVVAFASLFFILVSITTFCLETHEAFNIDRNVTEIHRVGNITSVRFRREVETEPILTYIEGVCVMWFTLEFLVRIVCCPDTLDFVKNLLNIIDFVAILPFYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRKKHVPRPPQLESPIYCKSEETSPRDSTYSDTSPPAREEGVVERKRADSKQNGDANAVLSDEEGAGLTQPLALAPTPEERRALRRSGTRDRNKKAAACFLLSAGDYACADGSVRKEGNVEPKACVPVSHTCAL", "length": 628 }, "evidence": [ { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96PR1-1", "protein_name": "Voltage-gated potassium channel KCNC2", "gene_name": "KCNC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKIENNERVILNVGGTRHETYRSTLKTLPGTRLALLASSEPPGDCLTTAGDKLQPSPPPLSPPPRAPPLSPGPGGCFEGGAGNCSSRGGRASDHPGGGREFFFDRHPGVFAYVLNYYRTGKLHCPADVCGPLFEEELAFWGIDETDVEPCCWMTYRQHRDAEEALDIFETPDLIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSPNKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPQASSPTFCKTELNMACNSTQSDTCLGKDNRLLEHNRSVLSGDDSTGSEPPLSPPERLPIRRSSTRDKNRRGETCFLLTTGDYTCASDGGIRKGYEKSRSLNNIAGLAGNALRLSPVTSPYNSPCPLRRSRSPIPSIL", "length": 638 }, "evidence": [ { "id": "FB:FBgn0085395", "url": "https://alliancegenome.org/gene/FB:FBgn0085395#orthology", "database": "AGR" }, { "id": "FB:FBgn0003386", "url": "https://alliancegenome.org/gene/FB:FBgn0003386#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein homooligomerization", "id": "GO:0051260", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051260", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37" } ], "pmid": "" }, { "name": "action potential", "id": "GO:0001508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001508", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071805", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "voltage-gated potassium channel complex", "id": "GO:0008076", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008076", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37" } ], "pmid": "" }, { "name": "presynaptic membrane", "id": "GO:0042734", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042734", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37" } ], "pmid": "" }, { "name": "axon terminus", "id": "GO:0043679", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043679", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37" } ], "pmid": "" }, { "name": "neuronal cell body membrane", "id": "GO:0032809", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032809", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37" } ], "pmid": "" }, { "name": "dendrite membrane", "id": "GO:0032590", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032590", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "voltage-gated potassium channel activity", "id": "GO:0005249", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005249", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG37", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG37" } ], "pmid": "" }, { "name": "delayed rectifier potassium channel activity", "id": "GO:0005251", "url": 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This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. 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"RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325962" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021325962.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325962", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325962" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P627", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P627" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100537597", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P627", "locus": {} } ], "crossref": [ { "id": "A0A8M9P627", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P627", "database": "AlphaFoldDB", "categories": [] }, { "id": "100537597", "url": "https://www.ncbi.nlm.nih.gov/gene/100537597", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100537597", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100537597", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P627", "url": "https://www.orthodb.org/?gene=A0A8M9P627", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_021325962", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325962", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P627", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P627", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P627-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P627-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ITX6", "url": "https://www.uniprot.org/uniprotkb/A0AC58ITX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ITX6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ITX6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVVLTWFTMCVSRMWILSYSLAVLLALGACDYNDIATVYAYSPGSSGGHFGSNNPSQSMQEVKQSVLDFYGGNVVAGPVSKDKWGFETGSYSSQAGSSGTPMTSEKPGSDSYTGSKQGFHVNSVGTGSLVYGSVGNAVNMGMSGYDSSLSTTVQGSEVTSSSVLSPLQQSSYSVSNPVQVVSSIPLHISSTSVVKPSSQQLVQTISQSSSEQPTSSGAIAQSNPLQLSLPSGKQIFQTSFQSAVPSGRWPLKPLKGKHHHKTGSRPAHNAPISSKPSKASHPSLSILQYGGVPDSLAMASYELVSQSGSQQSAQSSGQTVNQPGIIQTPSVIDVSVVQPSSQLIQQAVDYSVAQVSSQQLLQEGRLVSQSNNVQPVDGSYVFVAQPGGPTPLKHHKGKPHFGSKLSSTSPLQTLTFTSVDQSSSLKPVQTIYQSGPQFVQQPAQIIYQSASQPTVPQLVGAIYQSETQPASQQPAPASYQLVAQLGVQQPAQVSSSVGQPSHLQAGQSNYEYVVNQNGQTLFKPVQSHGIHQIGSKLYSCHELPQHGYKRRHHSPSTHSLPNAAQVIKPVLPSDPIPADLNFPSPLTTTFRPAHLSGHPSLQSVVLQSERPGVLEIQPSGLSHAKPGPVSYTLVSQPTGHPSRPLQQPSYQLPAKLWQNLFLPIVKPNKLELSSFEAQVLPSHVSSVPVQFVSQPQMLPASLSVTQSSLSPALPVQSSYQPQVVSSSETVLQTSSAVVPSSSQTWSTPVVSNFKSVLQSVKPELPIPVLLNYQTVTDQNAPGPAGSNRHSSWKLLKLLQQVKS", "length": 803, "header": "tr|A0A8M9P627-1|A0A8M9P627_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100537597 PE=1 SV=2 CANONICAL=A0A8M9P627-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P627-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P627/entry#A0A8M9P627-1", "sequence": { "sequence": "MVVLTWFTMCVSRMWILSYSLAVLLALGACDYNDIATVYAYSPGSSGGHFGSNNPSQSMQEVKQSVLDFYGGNVVAGPVSKDKWGFETGSYSSQAGSSGTPMTSEKPGSDSYTGSKQGFHVNSVGTGSLVYGSVGNAVNMGMSGYDSSLSTTVQGSEVTSSSVLSPLQQSSYSVSNPVQVVSSIPLHISSTSVVKPSSQQLVQTISQSSSEQPTSSGAIAQSNPLQLSLPSGKQIFQTSFQSAVPSGRWPLKPLKGKHHHKTGSRPAHNAPISSKPSKASHPSLSILQYGGVPDSLAMASYELVSQSGSQQSAQSSGQTVNQPGIIQTPSVIDVSVVQPSSQLIQQAVDYSVAQVSSQQLLQEGRLVSQSNNVQPVDGSYVFVAQPGGPTPLKHHKGKPHFGSKLSSTSPLQTLTFTSVDQSSSLKPVQTIYQSGPQFVQQPAQIIYQSASQPTVPQLVGAIYQSETQPASQQPAPASYQLVAQLGVQQPAQVSSSVGQPSHLQAGQSNYEYVVNQNGQTLFKPVQSHGIHQIGSKLYSCHELPQHGYKRRHHSPSTHSLPNAAQVIKPVLPSDPIPADLNFPSPLTTTFRPAHLSGHPSLQSVVLQSERPGVLEIQPSGLSHAKPGPVSYTLVSQPTGHPSRPLQQPSYQLPAKLWQNLFLPIVKPNKLELSSFEAQVLPSHVSSVPVQFVSQPQMLPASLSVTQSSLSPALPVQSSYQPQVVSSSETVLQTSSAVVPSSSQTWSTPVVSNFKSVLQSVKPELPIPVLLNYQTVTDQNAPGPAGSNRHSSWKLLKLLQQVKS", "length": 803, "header": "tr|A0A8M9P627-1|A0A8M9P627_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100537597 PE=1 SV=2 CANONICAL=A0A8M9P627-1" }, "locus": {} }, { "isoform_ac": "A0AC58ITX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P627/entry#A0AC58ITX6-1", "sequence": { "sequence": "MVVLTWFTMCVSRMWILSYSLAVLLALGACDYNDIATVYAYSPGSSGGHFGSNNPSQSMQEVKQSVLDFYGGNVVAGPVSKDKWGFETGSYSSQAGSSGTPMTSEKPGSDSYTGSKQGFHVNSVGTGSLVYGSVGNAVNMGMSGYDSSLSTTVQGSEVTSSSVLSPLQQSSYSVSNPVQVVSSIPLHISSTSVVKPSSQQLVQTISQSSSEQPTSSGAIAQSNPLQLSLPSGKQIFQTSFQSAVPSGRWPLKPLKGKHHHKTGSRPAHNAPISSKPSKASHPSLSILQYGGVPDSLAMASYELVSQSGSQQSAQSSGQTVNQPGIIQTPSVIDVSVVQPSSQLIQQAVDYSVAQVSSQQLLQEGRLVSQSNNVQPVDGSYVFVAQPGGPTPLKHHKDQSSSLKPVQTIYQSGPQFVQQPAQIIYQSASQPTVPQLVGAIYQSETQPASQQPAPASYQLVAQLGVQQPAQVSSSVGQPSHLQAGQSNYEYVVNQNGQTLFKPVQSHGIHQIGSKLYSCHELPQHGYKRRHHSPSTHSLPNAAQVIKPVLPSDPIPADLNFPSPLTTTFRPAHLSGHPSLQSVVLQSERPGVLEIQPSGLSHAKPGPVSYTLVSQPTGHPSRPLQQPSYQLPAKLWQNLFLPIVKPNKLELSSFEAQVLPSHVSSVPVQFVSQPQMLPASLSVTQSSLSPALPVQSSYQPQVVSSSETVLQTSSAVVPSSSQTWSTPVVSNFKSVLQSVKPELPIPVLLNYQTVTDQNAPGPAGSNRHSSWKLLKLLQQVKS", "length": 780, "header": "tr|A0AC58ITX6-1|A0AC58ITX6_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC100537597 PE=1 SV=1 CANONICAL=A0A8M9P627-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 390, "start_aa": "Thr", "end_pos": 390, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr390", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100537597", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100537597", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 390 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P6A2-1", "uniprot_ac": "A0A8M9P6A2", "uniprot_id": "A0A8M9P6A2_DANRE", "mass": { "chemical_mass": 49174.0, "monoisotopic_mass": 49174.0 }, "refseq": { "ac": "XP_021326082", "name": "putative protein MSS51 homolog, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326082" }, "gene_names": [ { "name": "LOC103908684", "type": "recommended", "evidence": [ { "id": "A0A8M9P6A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A2" } ] }, { "name": "LOC103908684", "type": "synonym", "evidence": [ { "id": "XP_021326082", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326082" } ] } ], "protein_names": [ { "name": "MYND-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9P6A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A2/entry#names_and_taxonomy" } ] }, { "name": "putative protein MSS51 homolog, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_021326082", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326082" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326082", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326082" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6A2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC103908684", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A2", "locus": {} } ], "crossref": [ { "id": "A0A8M9P6A2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P6A2", "database": "AlphaFoldDB", "categories": [] }, { "id": "103908684", "url": "https://www.ncbi.nlm.nih.gov/gene/103908684", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046824", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046824", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:103908684", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103908684", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P6A2", "url": "https://www.orthodb.org/?gene=A0A8M9P6A2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46920", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46920", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46920:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46920:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20179", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20179", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021326082", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326082", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P6A2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P6A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAGPVPALPGSFNPSADSVYSDQFGFYTMDYKVPGLSKVILDKLNMKDYKEYREALEGKGKVGFRSHKEMFQKLEETFKFCARCSKLPSDFADPKALKRCIKCLNVYYCSKECQKTDWSLHKKFCKMLHKVSIDRLVEWLIHTGDLPFPTEAWSRPAKDVRCWNDWLSMQGDLMGRLEPILSGQNMTDLWTNSCRPRPDEAELQKSVWRVCSEFFSRSLTIGLGIQMSRLDPYSRPLTVHLVGAGHNETLGARTTDLDELSHMFPGHQGLEVVMVGPEVVQGPIMRPPLRAFGPRGRVYISAYKGLYHEFWEEKVEKGEAAKPDLVVGFHPGFHASQGLGEGWLPTLLLLRDFNIPALFTVFNDEELQYSLQILLELEMDIKDSGPNPFSSQKPEQVQSSPNHSPSHCSAFYIYFQGLQETQTEQEETNTHS", "length": 432, "header": "tr|A0A8M9P6A2-1|A0A8M9P6A2_DANRE Isoform 1 of MYND-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC103908684 PE=4 SV=1 CANONICAL=A0A8M9P6A2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P6A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A2/entry#A0A8M9P6A2-1", "sequence": { "sequence": "MAGPVPALPGSFNPSADSVYSDQFGFYTMDYKVPGLSKVILDKLNMKDYKEYREALEGKGKVGFRSHKEMFQKLEETFKFCARCSKLPSDFADPKALKRCIKCLNVYYCSKECQKTDWSLHKKFCKMLHKVSIDRLVEWLIHTGDLPFPTEAWSRPAKDVRCWNDWLSMQGDLMGRLEPILSGQNMTDLWTNSCRPRPDEAELQKSVWRVCSEFFSRSLTIGLGIQMSRLDPYSRPLTVHLVGAGHNETLGARTTDLDELSHMFPGHQGLEVVMVGPEVVQGPIMRPPLRAFGPRGRVYISAYKGLYHEFWEEKVEKGEAAKPDLVVGFHPGFHASQGLGEGWLPTLLLLRDFNIPALFTVFNDEELQYSLQILLELEMDIKDSGPNPFSSQKPEQVQSSPNHSPSHCSAFYIYFQGLQETQTEQEETNTHS", "length": 432, "header": "tr|A0A8M9P6A2-1|A0A8M9P6A2_DANRE Isoform 1 of MYND-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC103908684 PE=4 SV=1 CANONICAL=A0A8M9P6A2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103908684", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103908684", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6A2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 247, "end_pos": 249, "annotation": "n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P6A2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A2" }, { "id": "PS50865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYND-type", "eco_id": "ECO_0000259", "start_pos": 81, "end_pos": 125, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 }, { "start_pos": 247, "end_pos": 249 }, { "start_pos": 402, "end_pos": 404 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P6A7-1", "uniprot_ac": "A0A8M9P6A7", "uniprot_id": "A0A8M9P6A7_DANRE", "mass": { "chemical_mass": 120464.0, "monoisotopic_mass": 120464.0 }, "refseq": { "ac": "XP_073797333", "name": "tetratricopeptide repeat protein 21A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073797333" }, "gene_names": [ { "name": "ttc21a", "type": "recommended", "evidence": [ { "id": "A0A8M9P6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7" } ] }, { "name": "ttc21a", "type": "synonym", "evidence": [ { "id": "XP_073797333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073797333" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 21A isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 21A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_073797333", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073797333" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073797333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073797333" } ] } ], "disease": [ { "disease_id": "DOID:0111927", "recommended_name": { "id": "DOID:0111927", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111927", "name": "spermatogenic failure 37", "description": "A spermatogenic failure characterized by multiple morphologic abnormalities of the flagella, asthenoteratozoospermia, and infertility that has_material_basis_in homozygous or compound heterozygous mutation in the TTC21A gene on chromosome 3p22.2." }, "synonyms": [ { "id": "DOID:0111927", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111927", "name": "SPGF37", "description": "" }, { "id": "MONDO:0032744", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032744", "name": "spermatogenic failure 37", "description": "" }, { "id": "MONDO:0032744", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0032744", "name": "SPGF37", "description": "" }, { "id": "MIM:618429", "resource": "MIM", "url": "https://www.omim.org/entry/618429", "name": "Spermatogenic failure 37", "description": "Spermatogenic failure 37" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111927", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111927" } ] }, { "disease_id": "DOID:12712", "recommended_name": { "id": "DOID:12712", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12712", "name": "nephronophthisis", "description": "A kidney disease that is characterized by a chronic tubulointerstitial nephritis that progress to terminal renal failure during the second decade (juvenile form) or before the age of 5 years (infantile form) resulting from dysfunction of ciliary proteins (ciliopathy)." }, "synonyms": [ { "id": "DOID:12712", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12712", "name": "medullary cystic disease", "description": "" }, { "id": "DOID:12712", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12712", "name": "medullary cystic kidney", "description": "" }, { "id": "MONDO:0009728", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009728", "name": "nephronophthisis 1", "description": "Progressive tubulointerstitial nephritis inherited in an autosomal recessive manner. It is caused by mutations in the NPHP1 gene. Patients present with anemia, polyuria, and polydipsia during childhood. The progressive bilateral kidney damage results in renal failure." }, { "id": "MONDO:0009728", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009728", "name": "NPH1", "description": "" }, { "id": "MONDO:0009728", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009728", "name": "NPHP1", "description": "" }, { "id": "MONDO:0009728", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009728", "name": "NPHP1 nephronophthisis (disease)", "description": "" }, { "id": "MONDO:0009728", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009728", "name": "familial juvenile nephronophthisis", "description": "" }, { "id": "MONDO:0009728", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009728", "name": "juvenile nephronophthisis", "description": "" }, { "id": "MONDO:0009728", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009728", "name": 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7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6A7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ttc21a", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141211-62", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141211-62", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P6A7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P6A7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100001597", "url": "https://www.ncbi.nlm.nih.gov/gene/100001597", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040364", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040364", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056833", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056833", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P6A7", "url": "https://www.orthodb.org/?gene=A0A8M9P6A7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14699", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14699", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14699:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14699:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25058", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25058", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25062", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25062", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25063", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25063", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25064", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25064", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25068", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25068", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073797333", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073797333", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P6A7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P6A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ISW4", "url": "https://www.uniprot.org/uniprotkb/A0AC58ISW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ISW4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ISW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ISW5", "url": "https://www.uniprot.org/uniprotkb/A0AC58ISW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ISW5-1", "url": 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"MSEEDKTCLPLIIYYMRERYYRHAINTAARSLKVYNNDPVLRFFKAFATLMEGHSQEALQELILLKDHPHLSLCSTVALIYAHKHCETVDEDAVNELNSELKRSGSTAGERALYYAALIYWILQMNLKAKTCIKKMLKISETSPEGLIMKGWIVLTSDLEENRPQAIRYFNSGVRDSGNLFGLMGKIEFFMLKQNESSALDIIHQILLIYPDFTPALLMKMKIFMALQDYEQTEDIAHRVLERDAQDLKALQMLTVIAVVKDGDTELVKQRQQALVSALELREPCNPSLHVEITAVISRLIRDQFQFNLIKAQALLRSGDVKSAIQCLNLIMKMPGVQGPSEGPQSSIISSSERLCVFLQLSEALRVNGDQHEAAKVLEDAVVFFRGMPEETQLTLAHVDLALTRDDVDAAVLILQNILPTESSYIQAREKMAHIYLERRNDKKLFIACYKEITEQLPGAHTSILLADAFMKIHQPEEAARIYQEVETIAPKCTLTKKIGHALVKAHEYDKAVCYYETALRRDSLDCVLSLELSELLLKLKRFNRAQQVLEQALDHQPTCALAAMMNDVKALRVLVKVLRARDESALDVIQKMHDLQLRVIIRVSSEHQAELEEQKKLLSSICCDWAQEFHLRHELEKAKRHYTDALNHRPDDQQVLLHLAALYYEQQKLDYCEELCVKILQLQQEHTAAAMLFADTLYWKNQKEEAVKIYTSIMKRNPDNFHAMAKFLQILRRMGKLEDAVSVFNACEKFNPLTLREAGYQYCKGLYLWHSHQTSSSLTHLNKARGDADWGKPALEMMIHICLNPDKIIFGGEILDKGLRENISESENEMRMNTAHNLLRMFHPRCRSEQDKAALLLNECRIYSRKHTQVETAVLELADTLANNVMLEECLLLMAEGFVQLKQIPRARNFLKRLTRMNWSDTNADYMEKGCLLLADMYIKMGKYTEGRTLLHRCTQHNKSCSKAYEYEGFMLENEQRYRDAALQYELAWRHSRQPAVGYRLALNYLKSQNYTLAVDVCRQVLQQHPDYPQINTEILTRARLSLRL", "length": 1046, "header": "tr|A0A8M9P6A7-1|A0A8M9P6A7_DANRE Isoform 1 of Tetratricopeptide repeat protein 21A isoform X1 OS=Danio rerio OX=7955 GN=ttc21a PE=3 SV=2 CANONICAL=A0A8M9P6A7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P6A7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7/entry#A0A8M9P6A7-1", "sequence": { "sequence": "MSEEDKTCLPLIIYYMRERYYRHAINTAARSLKVYNNDPVLRFFKAFATLMEGHSQEALQELILLKDHPHLSLCSTVALIYAHKHCETVDEDAVNELNSELKRSGSTAGERALYYAALIYWILQMNLKAKTCIKKMLKISETSPEGLIMKGWIVLTSDLEENRPQAIRYFNSGVRDSGNLFGLMGKIEFFMLKQNESSALDIIHQILLIYPDFTPALLMKMKIFMALQDYEQTEDIAHRVLERDAQDLKALQMLTVIAVVKDGDTELVKQRQQALVSALELREPCNPSLHVEITAVISRLIRDQFQFNLIKAQALLRSGDVKSAIQCLNLIMKMPGVQGPSEGPQSSIISSSERLCVFLQLSEALRVNGDQHEAAKVLEDAVVFFRGMPEETQLTLAHVDLALTRDDVDAAVLILQNILPTESSYIQAREKMAHIYLERRNDKKLFIACYKEITEQLPGAHTSILLADAFMKIHQPEEAARIYQEVETIAPKCTLTKKIGHALVKAHEYDKAVCYYETALRRDSLDCVLSLELSELLLKLKRFNRAQQVLEQALDHQPTCALAAMMNDVKALRVLVKVLRARDESALDVIQKMHDLQLRVIIRVSSEHQAELEEQKKLLSSICCDWAQEFHLRHELEKAKRHYTDALNHRPDDQQVLLHLAALYYEQQKLDYCEELCVKILQLQQEHTAAAMLFADTLYWKNQKEEAVKIYTSIMKRNPDNFHAMAKFLQILRRMGKLEDAVSVFNACEKFNPLTLREAGYQYCKGLYLWHSHQTSSSLTHLNKARGDADWGKPALEMMIHICLNPDKIIFGGEILDKGLRENISESENEMRMNTAHNLLRMFHPRCRSEQDKAALLLNECRIYSRKHTQVETAVLELADTLANNVMLEECLLLMAEGFVQLKQIPRARNFLKRLTRMNWSDTNADYMEKGCLLLADMYIKMGKYTEGRTLLHRCTQHNKSCSKAYEYEGFMLENEQRYRDAALQYELAWRHSRQPAVGYRLALNYLKSQNYTLAVDVCRQVLQQHPDYPQINTEILTRARLSLRL", "length": 1046, "header": "tr|A0A8M9P6A7-1|A0A8M9P6A7_DANRE Isoform 1 of Tetratricopeptide repeat protein 21A isoform X1 OS=Danio rerio OX=7955 GN=ttc21a PE=3 SV=2 CANONICAL=A0A8M9P6A7-1" }, "locus": {} }, { "isoform_ac": "A0AC58ISW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7/entry#A0AC58ISW4-1", "sequence": { "sequence": "MSEEDKTCLPLIIYYMRERYYRHAINTAARSLKVYNNDPVLRFFKAFATLMEGHSQEALQELILLKDHPHLSLCSTVALIYAHKHCETVDAVNELNSELKRSGSTAGERALYYAALIYWILQMNLKAKTCIKKMLKISETSPEGLIMKGWIVLTSDLEENRPQAIRYFNSGVRDSGNLFGLMGKIEFFMLKQNESSALDIIHQILLIYPDFTPALLMKMKIFMALQDYEQTEDIAHRVLERDAQDLKALQMLTVIAVVKDGDTELVKQRQQALVSALELREPCNPSLHVEITAVISRLIRDQFQFNLIKAQALLRSGDVKSAIQCLNLIMKMPGVQGPSEGPQSSIISSSERLCVFLQLSEALRVNGDQHEAAKVLEDAVVFFRGMPEETQLTLAHVDLALTRDDVDAAVLILQNILPTESSYIQAREKMAHIYLERRNDKKLFIACYKEITEQLPGAHTSILLADAFMKIHQPEEAARIYQEVETIAPKCTLTKKIGHALVKAHEYDKAVCYYETALRRDSLDCVLSLELSELLLKLKRFNRAQQVLEQALDHQPTCALAAMMNDVKALRVLVKVLRARDESALDVIQKMHDLQLRVIIRVSSEHQAELEEQKKLLSSICCDWAQEFHLRHELEKAKRHYTDALNHRPDDQQQKLDYCEELCVKILQLQQEHTAAAMLFADTLYWKNQKEEAVKIYTSIMKRNPDNFHAMAKFLQILRRMGKLEDAVSVFNACEKFNPLTLREAGYQYCKGLYLWHSHQTSSSLTHLNKARGDADWGKPALEMMIHICLNPDKIIFGGEILDKGLRENISESENEMRMNTAHNLLRMFHPRCRSEQDKAALLLNECRIYSRKHTQVETAVLELADTLANNVMLEECLLLMAEGFVQLKQIPRARNFLKRLTRMNWSDTNADYMEKGCLLLADMYIKMGKYTEGRTLLHRCTQHNKSCSKAYEYEGFMLENEQRYRDAALQYELAWRHSRQPAVGYRLALNYLKSQNYTLAVDVCRQVLQQHPDYPQINTEILTRARLSLRL", "length": 1032, "header": "tr|A0AC58ISW4-1|A0AC58ISW4_DANRE Computationally mapped isoform of Tetratricopeptide repeat protein 21A isoform X4 OS=Danio rerio OX=7955 GN=ttc21a PE=3 SV=1 CANONICAL=A0A8M9P6A7-1" }, "locus": {} }, { "isoform_ac": "A0AC58ISW5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7/entry#A0AC58ISW5-1", "sequence": { "sequence": "MSEEDKTCLPLIIYYMRERYYRHAINTAARSLKVYNNDPVLRFFKAFATLMEGHSQEALQELILLKDHPHLSLCSTVALIYAHKHCETVDAVNELNSELKRSGSTAGERALYYAALIYWILQMNLKAKTCIKKMLKISETSPEGLIMKGWIVLTSDLEENRPQAIRYFNSGVRDSGNLFGLMGKIEFFMLKQNESSALDIIHQILLIYPDFTPALLMKMKIFMALQDYEQTEDIAHRVLERDAQDLKALQMLTVIAVVKDGDTELVKQRQQALVSALELREPCNPSLHVEITAVISRLIRDQFQFNLIKAQALLRSGDVKSAIQCLNLIMKMPGVQGPSEGPQSSIISSSERLCVFLQLSEALRVNGDQHEAAKVLEDAVVFFRGMPEETQLTLAHVDLALTRDDVDAAVLILQNILPTESSYIQAREKMAHIYLERRNDKKLFIACYKEITEQLPGAHTSILLADAFMKIHQPEEAARIYQEVETIAPKCTLTKKIGHALVKAHEYDKAVCYYETALRRDSLDCVLSLELSELLLKLKRFNRAQQVLEQALDHQPTCALAAMMNDVKALRVLVKVLRARDESALDVIQKMHDLQLRVIIRVSSEHQAELEEQKKLLSSICCDWAQEFHLRHELEKAKRHYTDALNHRPDDQQVLLHLAALYYEQQKLDYCEELCVKILQLQQEHTAAAMLFADTLYWKNQKEEAVKIYTSIMKRNPDNFHAMAKFLQILRRMGKLEDAVSVFNACEKFNPLTLREAGYQYCKGLYLWHSHQTSSSLTHLNKARGDADWGKPALEMMIHICLNPDKIIFGGEILDKGLRENISESENEMRMNTAHNLLRMFHPRCRSEQDKAALLLNECRIYSRKHTQVETAVLELADTLANNVMLEECLLLMAEGFVQLKQIPRARNFLKRLTRMNWSDTNADYMEKGCLLLADMYIKMGKYTEGRTLLHRCTQHNKSCSKAYEYEGFMLENEQRYRDAALQYELAWRHSRQPAVGYRLALNYLKSQNYTLAVDVCRQVLQQHPDYPQINTEILTRARLSLRL", "length": 1044, "header": "tr|A0AC58ISW5-1|A0AC58ISW5_DANRE Computationally mapped isoform of Tetratricopeptide repeat protein 21A isoform X2 OS=Danio rerio OX=7955 GN=ttc21a PE=3 SV=1 CANONICAL=A0A8M9P6A7-1" }, "locus": {} }, { "isoform_ac": "A0AC58ISX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7/entry#A0AC58ISX4-1", "sequence": { "sequence": "MSEEDKTCLPLIIYYMRERYYRHAINTAARSLKVYNNDPVLRFFKAFATLMEGHSQEALQELILLKDHPHLSLCSTVALIYAHKHCETVDEDAVNELNSELKRSGSTAGERALYYAALIYWILQMNLKAKTCIKKMLKISETSPEGLIMKGWIVLTSDLEENRPQAIRYFNSGVRDSGNLFGLMGKIEFFMLKQNESSALDIIHQILLIYPDFTPALLMKMKIFMALQDYEQTEDIAHRVLERDAQDLKALQMLTVIAVVKDGDTELVKQRQQALVSALELREPCNPSLHVEITAVISRLIRDQFQFNLIKAQALLRSGDVKSAIQCLNLIMKMPGVQGPSEGPQSSIISSSERLCVFLQLSEALRVNGDQHEAAKVLEDAVVFFRGMPEETQLTLAHVDLALTRDDVDAAVLILQNILPTESSYIQAREKMAHIYLERRNDKKLFIACYKEITEQLPGAHTSILLADAFMKIHQPEEAARIYQEVETIAPKCTLTKKIGHALVKAHEYDKAVCYYETALRRDSLDCVLSLELSELLLKLKRFNRAQQVLEQALDHQPTCALAAMMNDVKALRVLVKVLRARDESALDVIQKMHDLQLRVIIRVSSEHQAELEEQKKLLSSICCDWAQEFHLRHELEKAKRHYTDALNHRPDDQQQKLDYCEELCVKILQLQQEHTAAAMLFADTLYWKNQKEEAVKIYTSIMKRNPDNFHAMAKFLQILRRMGKLEDAVSVFNACEKFNPLTLREAGYQYCKGLYLWHSHQTSSSLTHLNKARGDADWGKPALEMMIHICLNPDKIIFGGEILDKGLRENISESENEMRMNTAHNLLRMFHPRCRSEQDKAALLLNECRIYSRKHTQVETAVLELADTLANNVMLEECLLLMAEGFVQLKQIPRARNFLKRLTRMNWSDTNADYMEKGCLLLADMYIKMGKYTEGRTLLHRCTQHNKSCSKAYEYEGFMLENEQRYRDAALQYELAWRHSRQPAVGYRLALNYLKSQNYTLAVDVCRQVLQQHPDYPQINTEILTRARLSLRL", "length": 1034, "header": "tr|A0AC58ISX4-1|A0AC58ISX4_DANRE Computationally mapped isoform of Tetratricopeptide repeat protein 21A isoform X3 OS=Danio rerio OX=7955 GN=ttc21a PE=3 SV=1 CANONICAL=A0A8M9P6A7-1" }, "locus": {} }, { "isoform_ac": "A0AC58ISY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7/entry#A0AC58ISY4-1", "sequence": { "sequence": "MRERYYRHAINTAARSLKVYNNDPVLRFFKAFATLMEGHSQEALQELILLKDHPHLSLCSTVALIYAHKHCETVDEDAVNELNSELKRSGSTAGERALYYAALIYWILQMNLKAKTCIKKMLKISETSPEGLIMKGWIVLTSDLEENRPQAIRYFNSGVRDSGNLFGLMGKIEFFMLKQNESSALDIIHQILLIYPDFTPALLMKMKIFMALQDYEQTEDIAHRVLERDAQDLKALQMLTVIAVVKDGDTELIRDQFQFNLIKAQALLRSGDVKSAIQCLNLIMKMPGVQGPSEGPQSSIISSSERLCVFLQLSEALRVNGDQHEAAKVLEDAVVFFRGMPEETQLTLAHVDLALTRDDVDAAVLILQNILPTESSYIQAREKMAHIYLERRNDKKLFIACYKEITEQLPGAHTSILLADAFMKIHQPEEAARIYQEVETIAPKCTLTKKIGHALVKAHEYDKAVCYYETALRRDSLDCVLSLELSELLLKLKRFNRAQQVLEQALDHQPTCALAAMMNDVKALRVLVKVLRARDESALDVIQKMHDLQLRVIIRVSSEHQAELEEQKKLLSSICCDWAQEFHLRHELEKAKRHYTDALNHRPDDQQVLLHLAALYYEQQKLDYCEELCVKILQLQQEHTAAAMLFADTLYWKNQKEEAVKIYTSIMKRNPDNFHAMAKFLQILRRMGKLEDAVSVFNACEKFNPLTLREAGYQYCKGLYLWHSHQTSSSLTHLNKARGDADWGKPALEMMIHICLNPDKIIFGGEILDKGLRENISESENEMRMNTAHNLLRMFHPRCRSEQDKAALLLNECRIYSRKHTQVETAVLELADTLANNVMLEECLLLMAEGFVQLKQIPRARNFLKRLTRMNWSDTNADYMEKGCLLLADMYIKMGKYTEGRTLLHRCTQHNKSCSKAYEYEGFMLENEQRYRDAALQYELAWRHSRQPAVGYRLALNYLKSQNYTLAVDVCRQVLQQHPDYPQINTEILTRARLSLRL", "length": 998, "header": "tr|A0AC58ISY4-1|A0AC58ISY4_DANRE Computationally mapped isoform of Tetratricopeptide repeat protein 21A isoform X9 OS=Danio rerio OX=7955 GN=ttc21a PE=3 SV=1 CANONICAL=A0A8M9P6A7-1" }, "locus": {} }, { "isoform_ac": "A0AC58ISZ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7/entry#A0AC58ISZ6-1", "sequence": { "sequence": "MSEEDKTCLPLIIYYMRERYYRHAINTAARSLKVYNNDPVLRFFKAFATLMEGHSQEALQELILLKDHPHLSLCSTVALIYAHKHCETVDEDAVNELNSELKRSGSTAGERALYYAALIYWILQMNLKAKTCIKKMLKISETSPEGLIMKGWIVLTSDLEENRPQAIRYFNSGVRDSGNLFGLMGKIEFFMLKQNESSALDIIHQILLIYPDFTPALLMKMKIFMALQDYEQTEDIAHRVLERDAQDLKALQMLTVIAVVKDGDTELIRDQFQFNLIKAQALLRSGDVKSAIQCLNLIMKMPGVQGPSEGPQSSIISSSERLCVFLQLSEALRVNGDQHEAAKVLEDAVVFFRGMPEETQLTLAHVDLALTRDDVDAAVLILQNILPTESSYIQAREKMAHIYLERRNDKKLFIACYKEITEQLPGAHTSILLADAFMKIHQPEEAARIYQEVETIAPKCTLTKKIGHALVKAHEYDKAVCYYETALRRDSLDCVLSLELSELLLKLKRFNRAQQVLEQALDHQPTCALAAMMNDVKALRVLVKVLRARDESALDVIQKMHDLQLRVIIRVSSEHQAELEEQKKLLSSICCDWAQEFHLRHELEKAKRHYTDALNHRPDDQQVLLHLAALYYEQQKLDYCEELCVKILQLQQEHTAAAMLFADTLYWKNQKEEAVKIYTSIMKRNPDNFHAMAKFLQILRRMGKLEDAVSVFNACEKFNPLTLREAGYQYCKGLYLWHSHQTSSSLTHLNKARGDADWGKPALEMMIHICLNPDKIIFGGEILDKGLRENISESENEMRMNTAHNLLRMFHPRCRSEQDKAALLLNECRIYSRKHTQVETAVLELADTLANNVMLEECLLLMAEGFVQLKQIPRARNFLKRLTRMNWSDTNADYMEKGCLLLADMYIKMGKYTEGRTLLHRCTQHNKSCSKAYEYEGFMLENEQRYRDAALQYELAWRHSRQPAVGYRLALNYLKSQNYTLAVDVCRQVLQQHPDYPQINTEILTRARLSLRL", "length": 1013, "header": "tr|A0AC58ISZ6-1|A0AC58ISZ6_DANRE Computationally mapped isoform of Tetratricopeptide repeat protein 21A isoform X5 OS=Danio rerio OX=7955 GN=ttc21a PE=3 SV=1 CANONICAL=A0A8M9P6A7-1" }, "locus": {} }, { "isoform_ac": "A0AC58ISZ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7/entry#A0AC58ISZ7-1", "sequence": { "sequence": "MSEEDKTCLPLIIYYMRERYYRHAINTAARSLKVYNNDPVLRFFKAFATLMEGHSQEALQELILLKDHPHLSLCSTVALIYAHKHCETVDAVNELNSELKRSGSTAGERALYYAALIYWILQMNLKAKTCIKKMLKISETSPEGLIMKGWIVLTSDLEENRPQAIRYFNSGVRDSGNLFGLMGKIEFFMLKQNESSALDIIHQILLIYPDFTPALLMKMKIFMALQDYEQTEDIAHRVLERDAQDLKALQMLTVIAVVKDGDTELIRDQFQFNLIKAQALLRSGDVKSAIQCLNLIMKMPGVQGPSEGPQSSIISSSERLCVFLQLSEALRVNGDQHEAAKVLEDAVVFFRGMPEETQLTLAHVDLALTRDDVDAAVLILQNILPTESSYIQAREKMAHIYLERRNDKKLFIACYKEITEQLPGAHTSILLADAFMKIHQPEEAARIYQEVETIAPKCTLTKKIGHALVKAHEYDKAVCYYETALRRDSLDCVLSLELSELLLKLKRFNRAQQVLEQALDHQPTCALAAMMNDVKALRVLVKVLRARDESALDVIQKMHDLQLRVIIRVSSEHQAELEEQKKLLSSICCDWAQEFHLRHELEKAKRHYTDALNHRPDDQQQKLDYCEELCVKILQLQQEHTAAAMLFADTLYWKNQKEEAVKIYTSIMKRNPDNFHAMAKFLQILRRMGKLEDAVSVFNACEKFNPLTLREAGYQYCKGLYLWHSHQTSSSLTHLNKARGDADWGKPALEMMIHICLNPDKIIFGGEILDKGLRENISESENEMRMNTAHNLLRMFHPRCRSEQDKAALLLNECRIYSRKHTQVETAVLELADTLANNVMLEECLLLMAEGFVQLKQIPRARNFLKRLTRMNWSDTNADYMEKGCLLLADMYIKMGKYTEGRTLLHRCTQHNKSCSKAYEYEGFMLENEQRYRDAALQYELAWRHSRQPAVGYRLALNYLKSQNYTLAVDVCRQVLQQHPDYPQINTEILTRARLSLRL", "length": 999, "header": "tr|A0AC58ISZ7-1|A0AC58ISZ7_DANRE Computationally mapped isoform of Tetratricopeptide repeat protein 21A isoform X8 OS=Danio rerio OX=7955 GN=ttc21a PE=3 SV=1 CANONICAL=A0A8M9P6A7-1" }, "locus": {} }, { "isoform_ac": "A0AC58IT01-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7/entry#A0AC58IT01-1", "sequence": { "sequence": "MSEEDKTCLPLIIYYMRERYYRHAINTAARSLKVYNNDPVLRFFKAFATLMEGHSQEALQELILLKDHPHLSLCSTVALIYAHKHCETVDEDAVNELNSELKRSGSTAGERALYYAALIYWILQMNLKAKTCIKKMLKISETSPEGLIMKGWIVLTSDLEENRPQAIRYFNSGVRDSGNLFGLMGKIEFFMLKQNESSALDIIHQILLIYPDFTPALLMKMKIFMALQDYEQTEDIAHRVLERDAQDLKALQMLTVIAVVKDGDTELIRDQFQFNLIKAQALLRSGDVKSAIQCLNLIMKMPGVQGPSEGPQSSIISSSERLCVFLQLSEALRVNGDQHEAAKVLEDAVVFFRGMPEETQLTLAHVDLALTRDDVDAAVLILQNILPTESSYIQAREKMAHIYLERRNDKKLFIACYKEITEQLPGAHTSILLADAFMKIHQPEEAARIYQEVETIAPKCTLTKKIGHALVKAHEYDKAVCYYETALRRDSLDCVLSLELSELLLKLKRFNRAQQVLEQALDHQPTCALAAMMNDVKALRVLVKVLRARDESALDVIQKMHDLQLRVIIRVSSEHQAELEEQKKLLSSICCDWAQEFHLRHELEKAKRHYTDALNHRPDDQQQKLDYCEELCVKILQLQQEHTAAAMLFADTLYWKNQKEEAVKIYTSIMKRNPDNFHAMAKFLQILRRMGKLEDAVSVFNACEKFNPLTLREAGYQYCKGLYLWHSHQTSSSLTHLNKARGDADWGKPALEMMIHICLNPDKIIFGGEILDKGLRENISESENEMRMNTAHNLLRMFHPRCRSEQDKAALLLNECRIYSRKHTQVETAVLELADTLANNVMLEECLLLMAEGFVQLKQIPRARNFLKRLTRMNWSDTNADYMEKGCLLLADMYIKMGKYTEGRTLLHRCTQHNKSCSKAYEYEGFMLENEQRYRDAALQYELAWRHSRQPAVGYRLALNYLKSQNYTLAVDVCRQVLQQHPDYPQINTEILTRARLSLRL", "length": 1001, "header": "tr|A0AC58IT01-1|A0AC58IT01_DANRE Computationally mapped isoform of Tetratricopeptide repeat protein 21A isoform X7 OS=Danio rerio OX=7955 GN=ttc21a PE=3 SV=1 CANONICAL=A0A8M9P6A7-1" }, "locus": {} }, { "isoform_ac": "A0AC58IT02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7/entry#A0AC58IT02-1", "sequence": { "sequence": "MSEEDKTCLPLIIYYMRERYYRHAINTAARSLKVYNNDPVLRFFKAFATLMEGHSQEALQELILLKDHPHLSLCSTVALIYAHKHCETVDAVNELNSELKRSGSTAGERALYYAALIYWILQMNLKAKTCIKKMLKISETSPEGLIMKGWIVLTSDLEENRPQAIRYFNSGVRDSGNLFGLMGKIEFFMLKQNESSALDIIHQILLIYPDFTPALLMKMKIFMALQDYEQTEDIAHRVLERDAQDLKALQMLTVIAVVKDGDTELIRDQFQFNLIKAQALLRSGDVKSAIQCLNLIMKMPGVQGPSEGPQSSIISSSERLCVFLQLSEALRVNGDQHEAAKVLEDAVVFFRGMPEETQLTLAHVDLALTRDDVDAAVLILQNILPTESSYIQAREKMAHIYLERRNDKKLFIACYKEITEQLPGAHTSILLADAFMKIHQPEEAARIYQEVETIAPKCTLTKKIGHALVKAHEYDKAVCYYETALRRDSLDCVLSLELSELLLKLKRFNRAQQVLEQALDHQPTCALAAMMNDVKALRVLVKVLRARDESALDVIQKMHDLQLRVIIRVSSEHQAELEEQKKLLSSICCDWAQEFHLRHELEKAKRHYTDALNHRPDDQQVLLHLAALYYEQQKLDYCEELCVKILQLQQEHTAAAMLFADTLYWKNQKEEAVKIYTSIMKRNPDNFHAMAKFLQILRRMGKLEDAVSVFNACEKFNPLTLREAGYQYCKGLYLWHSHQTSSSLTHLNKARGDADWGKPALEMMIHICLNPDKIIFGGEILDKGLRENISESENEMRMNTAHNLLRMFHPRCRSEQDKAALLLNECRIYSRKHTQVETAVLELADTLANNVMLEECLLLMAEGFVQLKQIPRARNFLKRLTRMNWSDTNADYMEKGCLLLADMYIKMGKYTEGRTLLHRCTQHNKSCSKAYEYEGFMLENEQRYRDAALQYELAWRHSRQPAVGYRLALNYLKSQNYTLAVDVCRQVLQQHPDYPQINTEILTRARLSLRL", "length": 1011, "header": "tr|A0AC58IT02-1|A0AC58IT02_DANRE Computationally mapped isoform of Tetratricopeptide repeat protein 21A isoform X6 OS=Danio rerio OX=7955 GN=ttc21a PE=3 SV=1 CANONICAL=A0A8M9P6A7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A5K9-1", "protein_name": "Tetratricopeptide repeat domain 21A", "gene_name": "Ttc21a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSDDSSLMASIIYYCQEKYFHHVLQAANVGLERYSCDPVLQFFRAYGVLGEDRIHDAISELESLQSHPDTSLCAVIALLYAHKCCDTIDAEAIQELDSSLKEIRRTASGMALYYASLFLWFMGHHDKAREYVDHMLKVSSGSKEGYVLKGWVDLTSNKPHVVKKSIKYLEQGTQDTKDVLGLMGKAKYFMTQQNFSGALEVVNQVTLAYSNFLPALVLKMKLFLARQDWEQTIETGQRILEKDENNIDAWQILAVHELVKEGNTDRAADRVRNLIKALETGEPQNPNLHLKKILAVSRLCGRHQVVHRLVSGFLERTFMATPSCALVATELGYLFILQQQVKEASLWYKEAMKLEENRLAALAGSIWCQILQGQLEEAAHQLEFLKEVQLSLGKSEVLVFLQALVAAKKQKLEQEATALLKEAVELHFSNMQGLALSPEYFEKLDPLFLVCIAKEYLHFCPKQPRSPGQLVSPLLKQVAMILSPVVKVAPAMMEPLFVTAQVKFLSGELENAQSTLQRCLELDPTFVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVRDHPLYHFIKARALNKTGDYAEAIKTLKMIIKVPTSKAEEGRKSRGPSVRPSERASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGNADLALNMLRGITPKQPCYTEAKEKMASIYLHTRKDVRLYIGCYMELCEHLPGPHSSLLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYAKAINYYEAAQKISGQDFLCCELAELLLKLKKYHKAEKVLKQALERDSGVKDIPSLMDEVKCLLLLAKVYKSHKKEDVMETLNQALDLQSRILKRVPLEQPEMIPSQNQVAASICVQIGEHHLADKDYDSAMKSYKDALAYSPTDSKVVLELAQLYLLQGQLDLCEQHCAPLLEMEQTHERAAVVLADLMFRKQNYETAINLYRQVLEKAPDNFLVLNKLIDLLRRSGKLEEAPAFFELAKKVSSRVPLEPGFNYCQGIYCWHIGQPNEALRFLNKARKDSTWGQLATCYMVQICLNPDNEIVGGEAFESLVGDSNSASRKESQQHGVRTAEKLLREFYPHSESGQTQLRLLQSLCLLATREKANIEVALGAFIEMAQAEKDNIPALLAMAQAYVLLKQVPKARTQLKRLAKVPWMLDEAEDLEKSWLLLADIYCQGGKFDLALELLRRCLQYNKSCCRAYEYMGFIMEKEQSYKDAATNYELAWKYSHQANPAIGFKLAFNYLKDKKFVDAIEVCHSVLTEYPNYPKIREEILEKAQGSLRP", "length": 1314 }, "evidence": [ { "id": "HGNC:30761", "url": "https://alliancegenome.org/gene/HGNC:30761#orthology", "database": "AGR" }, { "id": "MGI:1921302", "url": "https://alliancegenome.org/gene/MGI:1921302#orthology", "database": "AGR" }, { "id": "RGD:1308806", "url": "https://alliancegenome.org/gene/RGD:1308806#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141211-62", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141211-62#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C0S4-1", "protein_name": "Tetratricopeptide repeat protein 21A", "gene_name": "Ttc21a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSDDSSLMASIIYYSQEKYFHHVLQAANVGLERYSSDPALQFFRAYGILGEDHIHDAISELEGIQSHPDTSLCAVIALLSAHKSCDTIDIEAVQELESSLKEIRRSASSTALYYASLFLWFMGHHDKAREYVDHMLKVSSGSKEGYVLKGWVDLTSSKPHVVKKSIKYLEQGTQDTKDVLGLMGKATYFMTQQNFSGALEVANQVTLACSNFLPALVLKMKLFLARQDWDQTIETGQRILEKDENNIDAWQILAVHELVKEGNTDRAADRVRNLIKALETGEPHNPNLHLKKILVISRLCGRHQVVHRLVSGFLERIFMATPSCALVATELGYLFILHQQVKEACLWYKEAMKLEENRLAALAGSIWCQILQGQLEEAAHQLEFLKEVQQSLGKSELLVFLQALVAAKKQRLEQEATALLKEAVEVHFSSMQGLALSPEYFEKLDPLFLVCIAKEYLHFCPKQPRSPGQLVSPLLKQVAMILSPVVKVAPAMMEPLYVTAQVKFLSGELENAQSTLQRCLELDPTFVDAHLLMSQIYLAQGNFAMCSHCLELGVSHNFQVRDHPLYHFIKARALNKTGDYAEAIKTLKMIIKVPTSKAEEGRKSQSPSVRPSERASILLELVEALRLNGELHEATKIMQDAINEFSGTPEEMRITVANVDLALSKGNVDLALNMLRGITPKQPCYTEAKEKMASIYLHTRKDVRLYIGCYVELCEHLPGPHSSLLLGDAFMNIQEPEKALEVYDEAYRKNPHDASLVSRIGQAYVKTHQYAKAINYYEAAQKISGQDFLCCELAELLLKLKKYHKAEKVLKQALERDSGVKDIPSMINEVKCLLLLAKVYKSHKKEEVMETLNLALDLQSRILKRVPLEQSEMIPFQNQLAASICIQIGEHHLAEKDYDSALKSYKDALAYSPTDSKVVLELAHLYLLLGQLDLCEQRCAPLLEMEQTHERAAVMLADLMFRRQNYETAINLYHQVLEKAPDNFLVLNKLVDLLRRSGKLEEAPAFFELAKKVSSRVPLEPGFNYCQGIYFWHIGQPNEALRFLNKARKDSTWGQLATCYMVQICLNPDNEIVGGEAFESLVGDSNSASRKESQQHGVRTAEKLLREFYPHSESGQTQLRLLQNLCLLATREKANVEVALGAFIEMAQAEKDSIPALLAMAQAYILLKQVPKARTQLKRLAKVPWTVDEAEDLEKSWLLLADIYCQGGKFDLALELLRRCLQYNKSCCRAYEYMGFIMEKEQSYKDAATNYELAWKYSHQANPAIGFKLAFNYLKDKKFVDAIEVCHSVLTEHPKYPKIREEILEKAQGSLRP", "length": 1314 }, "evidence": [ { "id": "HGNC:30761", "url": "https://alliancegenome.org/gene/HGNC:30761#orthology", "database": "AGR" }, { "id": "MGI:1921302", "url": "https://alliancegenome.org/gene/MGI:1921302#orthology", "database": "AGR" }, { "id": "RGD:1308806", "url": "https://alliancegenome.org/gene/RGD:1308806#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141211-62", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141211-62#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NDW8-1", "protein_name": "Tetratricopeptide repeat protein 21A", "gene_name": "TTC21A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSNDSSLMAGIIYYSQEKYFHHVQQAAAVGLEKFSNDPVLKFFKAYGVLKEEHIQDAISDLESIRHHPDVSLCSTMALIYAHKRCEIIDREAIQELEYSLKEIRKTVSGTALYYAGLFLWLIGRHDKAKEYIDRMLKISRGFREAYVLRGWVDLTSDKPHTAKKAIEYLEQGIQDTKDVLGLMGKAMYFMMQQNYSEALEVVNQITVTSGSFLPALVLKMQLFLARQDWEQTVEMGHRILEKDESNIDACQILTVHELAREGNMTTVSSLKTQKATNHVRNLIKALETREPENPSLHLKKIIVVSRLCGSHQVILGLVCSFIERTFMATPSYVHVATELGYLFILKNQVKEALLWYSEAMKLDKDGMAGLTGIILCHILEGHLEEAEYRLEFLKEVQKSLGKSEVLIFLQALLMSRKHKGEEETTALLKEAVELHFSSMQGIPLGSEYFEKLDPYFLVCIAKEYLLFCPKQPRLPGQIVSPLLKQVAVILNPVVKAAPALIDPLYLMAQVRYYSELENAQSILQRCLELDPASVDAHLLMCQIYLAQGNFGMCFHCLELGVSHNFQVRDHPLYHLIKARALNKAGDYPEAIKTLKMVIKLPALKKEEGRKFLRPSVQPSQRASILLELVEALRLNGELHEATKVMQDTINEFGGTPEENRITIANVDLVLSKGNVDVALNMLRNILPKQSCYMEAREKMANIYLQTLRDRRLYIRCYRELCEHLPGPHTSLLLGDALMSILEPEKALEVYDEAYRQNPHDASLASRIGHAYVKAHQYTEAIEYYEAAQKINGQDFLCCDLGKLLLKLKKVNKAEKVLKQALEHDIVQDIPSMMNDVKCLLLLAKVYKSHKKEAVIETLNKALDLQSRILKRVPLEQPEMIPSQKQLAASICIQFAEHYLAEKEYDKAVQSYKDVFSYLPTDNKVMLELAQLYLLQGHLDLCEQHCAILLQTEQNHETASVLMADLMFRKQKHEAAINLYHQVLEKAPDNFLVLHKLIDLLRRSGKLEDIPAFFELAKKVSSRVPLEPGFNYCRGIYCWHIGQPNEALKFLNKARKDSTWGQSAIYHMVQICLNPDNEVVGGEAFENQGAESNYMEKKELEQQGVSTAEKLLREFYPHSDSSQTQLRLLQGLCRLATREKANMEAALGSFIQIAQAEKDSVPALLALAQAYVFLKQIPKARMQLKRLAKTPWVLSEAEDLEKSWLLLADIYCQGSKFDLALELLRRCVQYNKSCYKAYEYMGFIMEKEQSYKDAVTNYKLAWKYSHHANPAIGFKLAFNYLKDKKFVEAIEICNDVLREHPDYPKIREEILEKARRSLRP", "length": 1320 }, "evidence": [ { "id": "HGNC:30761", "url": "https://alliancegenome.org/gene/HGNC:30761#orthology", "database": "AGR" }, { "id": "MGI:1921302", "url": "https://alliancegenome.org/gene/MGI:1921302#orthology", "database": "AGR" }, { "id": "RGD:1308806", "url": "https://alliancegenome.org/gene/RGD:1308806#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141211-62", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141211-62#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6A7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7" } ], "pmid": "" }, { "name": "intraciliary transport particle A", "id": "GO:0030991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030991", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6A7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein localization to cilium", "id": "GO:0061512", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061512", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6A7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7" } ], "pmid": "" }, { "name": "intraciliary retrograde transport", "id": "GO:0035721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035721", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6A7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1011, "end_pos": 1013, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 823, "end_pos": 825, "annotation": "n_glycosylation_sequon" }, { "start_pos": 919, "end_pos": 921, "annotation": "n_glycosylation_sequon" }, { "start_pos": 959, "end_pos": 961, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7" }, { "id": "PF25063", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25063" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetratricopeptide repeat protein 21A/21B C-terminal ARM", "eco_id": "ECO_0000259", "start_pos": 835, "end_pos": 1041, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7" }, { "id": "PF25062", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25062" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetratricopeptide repeat protein 21A/21B N-terminal ARM repeat", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 233, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7" }, { "id": "PF25064", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25064" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetratricopeptide repeat protein 21A/21B fifth ARM repeats", "eco_id": "ECO_0000259", "start_pos": 689, "end_pos": 804, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P6A7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6A7" }, { "id": "PF25068", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25068" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tetratricopeptide repeat protein 21A/21B fourth ARM", "eco_id": "ECO_0000259", "start_pos": 495, "end_pos": 647, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1011, "end_pos": 1013 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 823, "end_pos": 825 }, { "start_pos": 919, "end_pos": 921 }, { "start_pos": 959, "end_pos": 961 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P6H5-1", "uniprot_ac": "A0A8M9P6H5", "uniprot_id": "A0A8M9P6H5_DANRE", "mass": { "chemical_mass": 48727.0, "monoisotopic_mass": 48727.0 }, "refseq": { "ac": "NP_001417887", "name": "uncharacterized protein LOC777611", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417887" }, "gene_names": [ { "name": "zgc:153935", "type": "recommended", "evidence": [ { "id": "A0A8M9P6H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5" } ] }, { "name": "zgc:153935", "type": "synonym", "evidence": [ { "id": "NP_001417887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417887" }, { "id": "A0A8M9P6H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC777611", "type": "synonym", "evidence": [ { "id": "A0A8M9P6H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5/entry#names_and_taxonomy" } ] }, { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P6H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC777611", "type": "synonym", "evidence": [ { "id": "NP_001417887", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417887" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQQ01001209.1, SRR32588732.1820467.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505376, SAMEA3505378 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000025.1. On Jun 15, 2024 this sequence version replaced XP_021326206.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001417887", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417887" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6H5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061103-148", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-148", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd08330", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08330", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "777611", "url": "https://www.ncbi.nlm.nih.gov/gene/777611", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033516", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033516", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:777611", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:777611", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P6H5", "url": "https://www.orthodb.org/?gene=A0A8M9P6H5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35083:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35083:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15112", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15112", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001417887", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417887", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P6H5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P6H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IW14", "url": "https://www.uniprot.org/uniprotkb/A0AC58IW14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IW14-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IW14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IW15", "url": "https://www.uniprot.org/uniprotkb/A0AC58IW15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IW15-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IW15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IW21", "url": "https://www.uniprot.org/uniprotkb/A0AC58IW21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IW21-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IW21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061103-148", "url": "https://zfin.org/ZDB-GENE-061103-148", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSNSQPYRRFSDENYKNWLKIAESLHILRNSMQDFIEKETETYHKALLNKQQLSGQRCEQTCKNNKSLCQLCEYWKNEIVTNHNEGGRNVHWDNCRPHLWATNKWEVAKAYMPRGHKQHCEFAQFDISAILNFLSACKHFKPFLTKGENVKKVINVRNVVMHSPDLKMNNEDMNRHLETIFQFADMLNSKVSALSVLREKIEQFNNILDKNFNQTEVDGQHKDLKTMVDFQEVLNREQQALKDRIEYLITHFEGNLDKNENSPDMTTLMEFLHQNKDLLENLGPEVYKLKGMQTKLNQHEKQINNLTNRVDQLEKVKETTNTAGQSSSQITNYPKFIKDNRSWLINTVKNIDQILDDLSELHSESVANVKAKQTKQAMMRELLLYVNCERIAKDLFNALLKHEKRPMEERLKGL", "length": 414, "header": "tr|A0A8M9P6H5-1|A0A8M9P6H5_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A0A8M9P6H5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P6H5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5/entry#A0A8M9P6H5-1", "sequence": { "sequence": "MSNSQPYRRFSDENYKNWLKIAESLHILRNSMQDFIEKETETYHKALLNKQQLSGQRCEQTCKNNKSLCQLCEYWKNEIVTNHNEGGRNVHWDNCRPHLWATNKWEVAKAYMPRGHKQHCEFAQFDISAILNFLSACKHFKPFLTKGENVKKVINVRNVVMHSPDLKMNNEDMNRHLETIFQFADMLNSKVSALSVLREKIEQFNNILDKNFNQTEVDGQHKDLKTMVDFQEVLNREQQALKDRIEYLITHFEGNLDKNENSPDMTTLMEFLHQNKDLLENLGPEVYKLKGMQTKLNQHEKQINNLTNRVDQLEKVKETTNTAGQSSSQITNYPKFIKDNRSWLINTVKNIDQILDDLSELHSESVANVKAKQTKQAMMRELLLYVNCERIAKDLFNALLKHEKRPMEERLKGL", "length": 414, "header": "tr|A0A8M9P6H5-1|A0A8M9P6H5_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A0A8M9P6H5-1" }, "locus": {} }, { "isoform_ac": "A0AC58IW14-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5/entry#A0AC58IW14-1", "sequence": { "sequence": "MKGQKPNLIVGRRPKSLCQLCEYWKNEIVTNHNEGGRNVHWDNCRPHLWATNKWEVAKAYMPRGHKQHCEFAQFDISAILNFLSACKHFKPFLTKGENVKKVINVRNVVMHSPDLKMNNEDMNRHLETIFQFADMLNSKVSALSVLREKIEQFNNILDKNFNQTEVDGQHKDLKTMVDFQEVLNREQQALKDRIEYLITHFEGNLDKNENSPDMTTLMEFLHQNKDLLENLGPEVYKLKGMQTKLNQHEKQINNLTNRVDQLEKVKETTNTAGQSSSQITNYPKFIKDNRSWLINTVKNIDQILDDLSELHSESVANVKAKQTKQAMMRELLLYVNCERIAKDLFNALLKHEKRPMEERLKGL", "length": 363, "header": "tr|A0AC58IW14-1|A0AC58IW14_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=zgc:153935 PE=4 SV=1 CANONICAL=A0A8M9P6H5-1" }, "locus": {} }, { "isoform_ac": "A0AC58IW15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5/entry#A0AC58IW15-1", "sequence": { "sequence": "MPRGHKQHCEFAQFDISAILNFLSACKHFKPFLTKGENVKKVINVRNVVMHSPDLKMNNEDMNRHLETIFQFADMLNSKVSALSVLREKIEQFNNILDKNFNQTEVDGQHKDLKTMVDFQEVLNREQQALKDRIEYLITHFEGNLDKNENSPDMTTLMEFLHQNKDLLENLGPEVYKLKGMQTKLNQHEKQINNLTNRVDQLEKVKETTNTAGQSSSQITNYPKFIKDNRSWLINTVKNIDQILDDLSELHSESVANVKAKQTKQAMMRELLLYVNCERIAKDLFNALLKHEKRPMEERLKGL", "length": 303, "header": "tr|A0AC58IW15-1|A0AC58IW15_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=zgc:153935 PE=4 SV=1 CANONICAL=A0A8M9P6H5-1" }, "locus": {} }, { "isoform_ac": "A0AC58IW21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5/entry#A0AC58IW21-1", "sequence": { "sequence": "MRVVEMYTGTIAGHIYGPQINGKLQRHTCHVGTNSIVINVRNVVMHSPDLKMNNEDMNRHLETIFQFADMLNSKVSALSVLREKIEQFNNILDKNFNQTEVDGQHKDLKTMVDFQEVLNREQQALKDRIEYLITHFEGNLDKNENSPDMTTLMEFLHQNKDLLENLGPEVYKLKGMQTKLNQHEKQINNLTNRVDQLEKVKETTNTAGQSSSQITNYPKFIKDNRSWLINTVKNIDQILDDLSELHSESVANVKAKQTKQAMMRELLLYVNCERIAKDLFNALLKHEKRPMEERLKGL", "length": 298, "header": "tr|A0AC58IW21-1|A0AC58IW21_DANRE Computationally mapped isoform of Uncharacterized protein isoform X4 OS=Danio rerio OX=7955 GN=zgc:153935 PE=4 SV=1 CANONICAL=A0A8M9P6H5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6H5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6H5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] } ], "pathway": [ { "id": "dre:777611", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:777611", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q8C5K5-1", "protein_name": "Uncharacterized protein CXorf38 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVVSELAARLNCAEYKNWVKAGHCLLLLRSCLQGFIDREVLSFHRGLLAAVPGLGPHATCRGGSRCSPRARQFQPQCQVCAEWKHEILRHHINRNGDVHWGNCKPGLWPKDPWEVAKAFMPRGLADKRGPEECDAVALLSLINSCDHFVVDRKKVTEVIKCRNEIMHSSEMKVSSTWLRDFQIKIQNFLNEFKNIPEIVAVYSRIEQLLTSDWAVHIPEEDERDGCEFEIGSYLSVSQIHEIEIELLKEKLQEMYLQAAEEEMLPEEISNQLDVVKGFLGSNTDLRNGLTEDLQKLESLHLQHQKQTSKDAGRQTPERKA", "length": 320 }, "evidence": [ { "id": "MGI:1916405", "url": "https://alliancegenome.org/gene/MGI:1916405#orthology", "database": "AGR" }, { "id": "HGNC:28589", "url": "https://alliancegenome.org/gene/HGNC:28589#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-148", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-148#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TB03-1", "protein_name": "Uncharacterized protein CXorf38", "gene_name": "CXorf38", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLSELAARLNCAEYKNWVKAGHCLLLLRSCLQGFVGREVLSFHRGLLAAAPGLGPRAVCRGGSRCSPRARQFQPQCQVCAEWKREILRHHVNRNGDVHWGNCRPGRWPVDAWEVAKAFMPRGLADKQGPEECDAVALLSLINSCDHFVVDRKKVTEVIKCRNEIMHSSEMKVSSTWLRDFQMKIQNFLNEFKNIPEIVAVYSRIEQLLTSDWAVHIPEEDQRDGCECEMGTYLSESQVNEIEMQLLKEKLQEIYLQAEEQEVLPEELSNRLEVVKEFLRNNEDLRNGLTEDMQKLDSLCLHQKLDSQEPGRQTPDRKA", "length": 319 }, "evidence": [ { "id": "MGI:1916405", "url": "https://alliancegenome.org/gene/MGI:1916405#orthology", "database": "AGR" }, { "id": "HGNC:28589", "url": "https://alliancegenome.org/gene/HGNC:28589#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061103-148", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061103-148#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6H5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6H5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P6H5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P6H5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 213, "end_pos": 215 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9P724-1", "uniprot_ac": "A0A8M9P724", "uniprot_id": "A0A8M9P724_DANRE", "mass": { "chemical_mass": 45211.0, "monoisotopic_mass": 45211.0 }, "refseq": { "ac": "XP_021321983", "name": "P2Y purinoceptor 14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321983" }, "gene_names": [ { "name": "gpr206", "type": "recommended", "evidence": [ { "id": "A0A8M9P724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P724" } ] }, { "name": "gpr206", "type": "synonym", "evidence": [ { "id": "XP_021321983", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321983" } ] } ], "protein_names": [ { "name": "Probable G-protein coupled receptor 34", "type": "recommended", "evidence": [ { "id": "A0A8M9P724", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P724/entry#names_and_taxonomy" } ] }, { "name": "P2Y purinoceptor 14", "type": "synonym", "evidence": [ { "id": "XP_021321983", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321983" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021321983.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021321983", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321983" } ] }, { "annotation": "G-protein-coupled receptor of lysophosphatidylserine (LysoPS) that plays different roles in immune response. Acts a damage-sensing receptor that triggers tissue repair upon recognition of dying neutrophils. Mechanistically, apoptotic neutrophils release lysophosphatydilserine that are recognized by type 3 innate lymphoid cells (ILC3s) via GPR34, which activates downstream PI3K-AKT and RAS-ERK signaling pathways leading to STAT3 activation and IL-22 production. Plays an important role in microglial function, controlling morphology and phagocytosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P724", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P724#function" }, { "database": "UniProtKB", "id": "ARBA00045234", "url": "https://www.uniprot.org/uniprotkb/ARBA00045234#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P724", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P724" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gpr206", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P724", "locus": {} } ], "crossref": [ { "id": "A0A8M9P724", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P724", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14982", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PTHR24233:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24233:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021321983", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321983", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P724", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P724", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P724-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P724-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 50, "end_pos": 52 }, { "start_pos": 57, "end_pos": 59 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P729-1", "uniprot_ac": "A0A8M9P729", "uniprot_id": "A0A8M9P729_DANRE", "mass": { "chemical_mass": 6778.0, "monoisotopic_mass": 6778.0 }, "refseq": { "ac": "XP_021321988", "name": "calmodulin regulator protein PCP4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321988" }, "gene_names": [ { "name": "pcp4b", "type": "recommended", "evidence": [ { "id": "A0A8M9P729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P729" } ] }, { "name": "pcp4b", "type": "synonym", "evidence": [ { "id": "XP_021321988", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321988" } ] } ], "protein_names": [ { "name": "Calmodulin regulator protein PCP4", "type": "synonym", "evidence": [ { "id": "A0A8M9P729", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P729/entry#names_and_taxonomy" } ] }, { "name": "calmodulin regulator protein PCP4", "type": "synonym", "evidence": [ { "id": "XP_021321988", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321988" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021321988", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321988" } ] } ], "disease": [ { "disease_id": "DOID:127", "recommended_name": { "id": "DOID:127", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:127", "name": "leiomyoma", "description": "A cell type benign neoplasm that is a benign tumor of smooth muscle cells." }, "synonyms": [ { "id": "DOID:127", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:127", "name": "leiomyomatous neoplasm", "description": "" }, { "id": "DOID:127", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:127", "name": "leiomyomatous tumor", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "127", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:127" } ] }, { "disease_id": "DOID:12858", "recommended_name": { "id": "DOID:12858", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12858", "name": "Huntington's disease", "description": "A neurodegenerative disease that has_material_basis_in autosomal dominant inheritance and is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities." }, "synonyms": [ { "id": "DOID:12858", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12858", "name": "HD", "description": "" }, { "id": "DOID:12858", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12858", "name": "Huntington disease", "description": "" }, { "id": "DOID:12858", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12858", "name": "Huntington's chorea", "description": "" }, { "id": "MONDO:0007739", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007739", "name": "Huntington disease", "description": "Huntington disease (HD) is a rare neurodegenerative disorder of the central nervous system characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia." }, { "id": "MONDO:0007739", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007739", "name": "HD", "description": "" }, { "id": "MONDO:0007739", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007739", "name": "Huntington chorea", "description": "" }, { "id": "MONDO:0007739", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007739", "name": "Huntington disease", "description": "" }, { "id": "MONDO:0007739", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007739", "name": "Huntington's Disease", "description": "" }, { "id": "MONDO:0007739", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007739", "name": "Huntington's chorea", "description": "" }, { "id": "MONDO:0007739", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007739", "name": "Huntington's disease", "description": "" }, { "id": "MIM:143100", "resource": "MIM", "url": "https://www.omim.org/entry/143100", "name": "Huntington disease", "description": "Huntington disease" } ], "unlinked_id_list": [], "evidence": [ { "id": "12858", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12858" } ] }, { "disease_id": "DOID:1824", "recommended_name": { "id": "DOID:1824", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1824", "name": "status epilepticus", "description": "" }, "synonyms": [ { "id": "DOID:1824", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1824", "name": "Grand mal status", "description": "" } ], 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"https://www.uniprot.org/uniprotkb/A0A8M9P729", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P729-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P729-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-031118-117", "url": "https://zfin.org/ZDB-GENE-031118-117", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSERQGSGAAGGNSKTSGAQDASKKDVPEDFDIDMDAPETEKAAVAIQSQFRKFQKKKNDDKS", "length": 63, "header": "tr|A0A8M9P729-1|A0A8M9P729_DANRE Isoform 1 of Calmodulin regulator protein PCP4 OS=Danio rerio OX=7955 GN=pcp4b PE=3 SV=1 CANONICAL=A0A8M9P729-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P729-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P729/entry#A0A8M9P729-1", "sequence": { "sequence": "MSERQGSGAAGGNSKTSGAQDASKKDVPEDFDIDMDAPETEKAAVAIQSQFRKFQKKKNDDKS", "length": 63, "header": "tr|A0A8M9P729-1|A0A8M9P729_DANRE Isoform 1 of Calmodulin regulator protein PCP4 OS=Danio rerio OX=7955 GN=pcp4b PE=3 SV=1 CANONICAL=A0A8M9P729-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:386963", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:386963", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P48539-1", "protein_name": "Calmodulin regulator protein PCP4", "gene_name": "PCP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSERQGAGATNGKDKTSGENDGQKKVQEEFDIDMDAPETERAAVAIQSQFRKFQKKKAGSQS", "length": 62 }, "evidence": [ { "id": "RGD:3271", "url": "https://alliancegenome.org/gene/RGD:3271#orthology", "database": "AGR" }, { "id": "MGI:97509", "url": "https://alliancegenome.org/gene/MGI:97509#orthology", "database": "AGR" }, { "id": "HGNC:8742", "url": "https://alliancegenome.org/gene/HGNC:8742#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-031118-117", "url": 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"database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885087", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885087", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P7A9", "url": "https://www.orthodb.org/?gene=A0A8M9P7A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24401", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24401", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24401:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24401:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021326567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326567", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P7A9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P7A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7A9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFLFYDYMYFCDYFQQSTASAAPAQTVQQPAPTVPAQEVMETRQLEAQPQPPSTPSVASKISPQLSMFTKPRFSRSHIAAAKPNLSVARRPSQADVQPSSAVCSASTPSTATQDLQVSAPVLTSTAAVTSSTEPSSIVSTAPSGSLLQAPSAVPLPRLWAETLPPEDHKWIASRLFKMGSKGKPELRDNLQLWYYPPQPALTYNQAPAPDRFFCHSLLLWMPYKLWRVKVLCPNPACGQHQLTGGGLHKRARQVLDIDRMYNMVTETLICTKCKASHVSWSQTVLQQLDLGHRSEFRVILTQKYACDIRVIRLLRERGLGNSPTRVIKQLKENHSEEWLQRLARYTTQCVDFLSGPGVLPITFQEPPAPTVVPSGKWLLTVYSQDILTRLNEIHARITSTHGSILKMDSTKKITKKLAGTARGTGLWLTSVGNEFGQVLISVLTAQEGAGLDRMVDGLVRRYQEAGVDPPAVLYVDCGCCTDVGETKLKARFRGWPELTVKLDIWHFMRRIAVGCTTDAHQLYPIFMSRISACIFEWDAADVSLLRQAKRALLMSQGWPALTDADVNKHLTREELALHCRRRTRGEETTILLLEQLLTELMSNKGNDSLGVPLLDKERMEHIWSVQKKHIKCIQDPPGVVLYTETGSITKGDVLLWTYRCARGSTSLESFHLHLNRFIPGYSANSLNFQIYLLEGLNRWNQDREAASLASEPSALRSYTGELVHCVNCNFEKLFGRNMVPNFCPPACYTGELIGVQYLFQQTGQVLQNINPDCEQTAELIEDLNVDEREEDEGFCDISEDHTIVDPEAALSPSPSTLRSGSSTAVTCSVASLPVSTCPALVPDPPEQPEEPISPVPLEPEEATEDDDEDNDDDDDDDGDEDTAVDYQNIPGFQHVDRLAEYLVELRTHKSLSLTNQEANEIIGLWQSLHDQDKKRVVYAARHQKRLLSGRFKTPKKPTHTPGVESTTRCVLGASSAPAQWPDCCRLVETIFIRLCTIHPSPK", "length": 1003, "header": "tr|A0A8M9P7A9-1|A0A8M9P7A9_DANRE Isoform 1 of DUF6729 domain-containing protein OS=Danio rerio OX=7955 GN=LOC101885087 PE=4 SV=2 CANONICAL=A0A8M9P7A9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P7A9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7A9/entry#A0A8M9P7A9-1", "sequence": { "sequence": "MPFLFYDYMYFCDYFQQSTASAAPAQTVQQPAPTVPAQEVMETRQLEAQPQPPSTPSVASKISPQLSMFTKPRFSRSHIAAAKPNLSVARRPSQADVQPSSAVCSASTPSTATQDLQVSAPVLTSTAAVTSSTEPSSIVSTAPSGSLLQAPSAVPLPRLWAETLPPEDHKWIASRLFKMGSKGKPELRDNLQLWYYPPQPALTYNQAPAPDRFFCHSLLLWMPYKLWRVKVLCPNPACGQHQLTGGGLHKRARQVLDIDRMYNMVTETLICTKCKASHVSWSQTVLQQLDLGHRSEFRVILTQKYACDIRVIRLLRERGLGNSPTRVIKQLKENHSEEWLQRLARYTTQCVDFLSGPGVLPITFQEPPAPTVVPSGKWLLTVYSQDILTRLNEIHARITSTHGSILKMDSTKKITKKLAGTARGTGLWLTSVGNEFGQVLISVLTAQEGAGLDRMVDGLVRRYQEAGVDPPAVLYVDCGCCTDVGETKLKARFRGWPELTVKLDIWHFMRRIAVGCTTDAHQLYPIFMSRISACIFEWDAADVSLLRQAKRALLMSQGWPALTDADVNKHLTREELALHCRRRTRGEETTILLLEQLLTELMSNKGNDSLGVPLLDKERMEHIWSVQKKHIKCIQDPPGVVLYTETGSITKGDVLLWTYRCARGSTSLESFHLHLNRFIPGYSANSLNFQIYLLEGLNRWNQDREAASLASEPSALRSYTGELVHCVNCNFEKLFGRNMVPNFCPPACYTGELIGVQYLFQQTGQVLQNINPDCEQTAELIEDLNVDEREEDEGFCDISEDHTIVDPEAALSPSPSTLRSGSSTAVTCSVASLPVSTCPALVPDPPEQPEEPISPVPLEPEEATEDDDEDNDDDDDDDGDEDTAVDYQNIPGFQHVDRLAEYLVELRTHKSLSLTNQEANEIIGLWQSLHDQDKKRVVYAARHQKRLLSGRFKTPKKPTHTPGVESTTRCVLGASSAPAQWPDCCRLVETIFIRLCTIHPSPK", "length": 1003, "header": "tr|A0A8M9P7A9-1|A0A8M9P7A9_DANRE Isoform 1 of DUF6729 domain-containing protein OS=Danio rerio OX=7955 GN=LOC101885087 PE=4 SV=2 CANONICAL=A0A8M9P7A9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 108, "start_aa": "Thr", "end_pos": 108, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr108", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 34, "start_aa": "Thr", "end_pos": 34, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr34", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 371, "start_aa": "Thr", "end_pos": 371, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr371", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101885087", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885087", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P7A9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7A9" }, { "id": "PF20499", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20499" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF6729", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 388, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 34, 55, 108, 371 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 334, "end_pos": 336 }, { "start_pos": 607, "end_pos": 609 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P7F8-1", "uniprot_ac": "A0A8M9P7F8", "uniprot_id": "A0A8M9P7F8_DANRE", "mass": { "chemical_mass": 193263.0, "monoisotopic_mass": 193263.0 }, "refseq": { "ac": "XP_021326632", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326632" }, "gene_names": [ { "name": "LOC110438472", "type": "recommended", "evidence": [ { "id": "A0A8M9P7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7F8" } ] }, { "name": "LOC110438472", "type": "synonym", "evidence": [ { "id": "XP_021326632", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326632" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9P7F8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7F8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021326632", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326632" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021326632.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326632", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326632" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P7F8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7F8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438472", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7F8", "locus": {} } ], "crossref": [ { "id": "A0A8M9P7F8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P7F8", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438472", "url": "https://www.ncbi.nlm.nih.gov/gene/110438472", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:110438472", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438472", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P7F8", "url": "https://www.orthodb.org/?gene=A0A8M9P7F8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_021326632", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326632", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P7F8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7F8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P7F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7F8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MQGYMWNSNQHTPARYLERPPPPYPQQFPPKYQAVRNDQPNAFQALFNQPNAFQAQFNQPIPQAQHFATPARYSNGQQEATNQWNAYSDSGDRFVHGFQSNSRGYDQTRQPNQIQPFTGSNLQSYCQSEKPNTYMYYNQSNTQSNASCPQTYRNTDCSQTPMYWTSQSNNGSSVGNNRGWTNHVSNNGNSSSMSNQQQFQSQRRIPAYYYHQQQQQQQQQQQQQQQQQQQQHQFSRQQSGKWQKKKHSTKGHQQRSTSYNNSQAQNQKASIDNSSNPTTAPSGESNSMSLPSNNLHQRPVFRPELRVNPGPDVSATQSQSNQSVGHQTQRTNCGTYNAMQTAQTIQANEAQPPVHSKIINSLIYKLLCSDSKKEANVQQSIAHQNTGPQQSEVCATDRTDHNSVEQFQPPNKSMKHGVDQRGYWDKDRSLSKDRTDLGMQSDVPRTLQTTIDENRLKIMNQHNIHYSTDPADCLEAVIALQRAAQQGHKAIAIVPPISQQPLTNAQIVDTTPKKPDSPPLKIASVWSLGDKSDAQKSISESPSHTPQQDDKSIENDTESSTELDTSSVSTVECQNDVQQGTSDLSKPSFDLSSVPVVEYNLEKLRDLVNTLERTEFSERLPEHSEFVLDRILKIYWNGNEDSIWEPLGSLINESPQSFEGIVRDVESVVFESVETENLQKLVNCNILKSGMYSSSEEFRSSWLNIDGQPADIEGVLSEALADDITVYNMTSENTDVTSPDIDVNYLKYLPEISTSEKSVKLSTCNQADLSTPLAGSDKEATASENNGHSYVVSSPSKMQMQNDTDQSHTLNTNGSGLSPLAESLTEKPTNNKSQSFKQDHSKQLCDNVFVSQSLSDDVSDGVKSSEKCLSTETLCQAMDICQVRDISDNEKPDNTKTLNNSSETWPVEDISEDENSGNKDVPPNATDTWIVEDISEDENSGSKDLPLNTIDTLVVEDISEDENCGNKKVPPNATDTWIVEDISDDDSENKIVSLKATDTWLVEDISEDEHSGNKQVPPNASNAWVVEDISDNIHCGNIKVLPDASDIWQVEDISDNENSGDKEVPPNASEIWQVEDISDDENSADKDTLSDSSDICIVEDVSNDENSSDDPMSMELTVLSFEDANTIFHHIEDEPECAIKAKSDCPNLAACSDVPNHEYYKTTICSLCSSNIVSSNSTDSIKTNHGGDGQLCLQCWEQAPLLELEDEPDILGSPAKSNDQSEDNLKHKKPNVDAPVTCIAEEGLTIPKRDSVVKSQLGENCCQPSQVKKPTVPLLEECAELKQKPSPPSPKPESKNSTLGLTEQCIELKQKCMPISVESEVKKPTVASKEQSNELTPTHSLLFRELVKKPAVVSTEECNALEGLTGPGRDHMVNSELGQRHRLPSTDFNAQESTCASPGTSIAEEQMTVQKSNFMETLQLKQNRNEPCLTLQGSSTASAVQHGLVLQKFGNMAKGVTKTLPKTPKSAKRESNKKKLKIKMTFPKRKKPPSTPSASSKHNPKSASPSTVPDECVLFAPDIVVKKICPQKKNLPAVPATKRPSVECNKMNKSKERRPEIKDINSLTQTESIQKRIEKESEDSSTSPIHRSGNEFELHGILTVNKTKATVPKKVRFDLFGSKTEEQSYAKERRFSAPATLTVSDSCNDYTDVLSAKQKVHNLWSSTFIPQKKNFYNRSQQEGTPQKNKTLKHYEHLKSNMSALKDQLTQRAMLLSNGEVQSSHFRKPFSRQKLSKTLSS", "length": 1736, "header": "tr|A0A8M9P7F8-1|A0A8M9P7F8_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC110438472 PE=4 SV=2 CANONICAL=A0A8M9P7F8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P7F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7F8/entry#A0A8M9P7F8-1", "sequence": { "sequence": "MQGYMWNSNQHTPARYLERPPPPYPQQFPPKYQAVRNDQPNAFQALFNQPNAFQAQFNQPIPQAQHFATPARYSNGQQEATNQWNAYSDSGDRFVHGFQSNSRGYDQTRQPNQIQPFTGSNLQSYCQSEKPNTYMYYNQSNTQSNASCPQTYRNTDCSQTPMYWTSQSNNGSSVGNNRGWTNHVSNNGNSSSMSNQQQFQSQRRIPAYYYHQQQQQQQQQQQQQQQQQQQQHQFSRQQSGKWQKKKHSTKGHQQRSTSYNNSQAQNQKASIDNSSNPTTAPSGESNSMSLPSNNLHQRPVFRPELRVNPGPDVSATQSQSNQSVGHQTQRTNCGTYNAMQTAQTIQANEAQPPVHSKIINSLIYKLLCSDSKKEANVQQSIAHQNTGPQQSEVCATDRTDHNSVEQFQPPNKSMKHGVDQRGYWDKDRSLSKDRTDLGMQSDVPRTLQTTIDENRLKIMNQHNIHYSTDPADCLEAVIALQRAAQQGHKAIAIVPPISQQPLTNAQIVDTTPKKPDSPPLKIASVWSLGDKSDAQKSISESPSHTPQQDDKSIENDTESSTELDTSSVSTVECQNDVQQGTSDLSKPSFDLSSVPVVEYNLEKLRDLVNTLERTEFSERLPEHSEFVLDRILKIYWNGNEDSIWEPLGSLINESPQSFEGIVRDVESVVFESVETENLQKLVNCNILKSGMYSSSEEFRSSWLNIDGQPADIEGVLSEALADDITVYNMTSENTDVTSPDIDVNYLKYLPEISTSEKSVKLSTCNQADLSTPLAGSDKEATASENNGHSYVVSSPSKMQMQNDTDQSHTLNTNGSGLSPLAESLTEKPTNNKSQSFKQDHSKQLCDNVFVSQSLSDDVSDGVKSSEKCLSTETLCQAMDICQVRDISDNEKPDNTKTLNNSSETWPVEDISEDENSGNKDVPPNATDTWIVEDISEDENSGSKDLPLNTIDTLVVEDISEDENCGNKKVPPNATDTWIVEDISDDDSENKIVSLKATDTWLVEDISEDEHSGNKQVPPNASNAWVVEDISDNIHCGNIKVLPDASDIWQVEDISDNENSGDKEVPPNASEIWQVEDISDDENSADKDTLSDSSDICIVEDVSNDENSSDDPMSMELTVLSFEDANTIFHHIEDEPECAIKAKSDCPNLAACSDVPNHEYYKTTICSLCSSNIVSSNSTDSIKTNHGGDGQLCLQCWEQAPLLELEDEPDILGSPAKSNDQSEDNLKHKKPNVDAPVTCIAEEGLTIPKRDSVVKSQLGENCCQPSQVKKPTVPLLEECAELKQKPSPPSPKPESKNSTLGLTEQCIELKQKCMPISVESEVKKPTVASKEQSNELTPTHSLLFRELVKKPAVVSTEECNALEGLTGPGRDHMVNSELGQRHRLPSTDFNAQESTCASPGTSIAEEQMTVQKSNFMETLQLKQNRNEPCLTLQGSSTASAVQHGLVLQKFGNMAKGVTKTLPKTPKSAKRESNKKKLKIKMTFPKRKKPPSTPSASSKHNPKSASPSTVPDECVLFAPDIVVKKICPQKKNLPAVPATKRPSVECNKMNKSKERRPEIKDINSLTQTESIQKRIEKESEDSSTSPIHRSGNEFELHGILTVNKTKATVPKKVRFDLFGSKTEEQSYAKERRFSAPATLTVSDSCNDYTDVLSAKQKVHNLWSSTFIPQKKNFYNRSQQEGTPQKNKTLKHYEHLKSNMSALKDQLTQRAMLLSNGEVQSSHFRKPFSRQKLSKTLSS", 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"url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322218" }, { "id": "A0A8M9P7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7L0" } ] } ], "protein_names": [ { "name": "Olfactory receptor 52K1-like", "type": "synonym", "evidence": [ { "id": "A0A8M9P7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7L0/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor 52K1-like", "type": "synonym", "evidence": [ { "id": "XP_021322218", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322218" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322218.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322218" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P7L0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7L0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "or55a3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7L0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-161017-131", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-161017-131", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P7L0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P7L0", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR000276", "url": 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"ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRDPPVQNTSFTDFKLNGFYSLGDLRPFLFIPFFLMFSLAITANSLLIYLIISQRSLHSPMYILIGLMGVVDLLLPVFFVPNMLLNFLFNWSGISLTACLIQMFCLHFVGTFQTTLLLCMALDRYFAICKPLYYHKYKEISNFLKFVFAPVIRNALLIVIIVSLAGRLSFCATNVIDHCFCEHMALVQLACGDISINNIVGLLTVFFVPATDFILITASYVVIFTSVFKSGETRMKALHTCITHLIVLSVALTSAMIAFLSYRIRNDISSNNRIVISVMYLCFPSCFNPIIYGWRTKEIRQMFLKFIKNKLYPLK", "length": 315, "header": "tr|A0A8M9P7L0-1|A0A8M9P7L0_DANRE Isoform 1 of Olfactory receptor 52K1-like OS=Danio rerio OX=7955 GN=or55a3 PE=3 SV=2 CANONICAL=A0A8M9P7L0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P7L0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P7L0/entry#A0A8M9P7L0-1", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326892" } ] } ], "disease": [ { "disease_id": "DOID:10941", "recommended_name": { "id": "DOID:10941", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10941", "name": "intracranial aneurysm", "description": "" }, "synonyms": [ { "id": "DOID:10941", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10941", "name": "brain aneurysm", "description": "" } ], "unlinked_id_list": [ "DOID:0060228" ], "evidence": [ { "id": "10941", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10941" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P800", "url": 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Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100006043", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006043", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF120", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF120", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021326892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326892", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P800", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P800", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P800-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P800-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090312-167", "url": "https://zfin.org/ZDB-GENE-090312-167", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAATLLTMSAALAPGQDDFLSLLKPSLSDGFQQDSSLFCFEHKIPDSERGLSNDYSQAKLEMDKYLSPQPVVLPDLKKSRRESVSTMDQYFGDDHGSPYSINMNVYLPDIAYLRTGLCRAARHSVSNQVKTEPVTAPFSHPECPVSSSGPAPSALPDFTSIFNSNSTSGSGMDVVDDSAGVFVKQEMQGFDIPQDGPLFQLLNSELDVPDPTDPHAHSQMPTFHNLHLAAQQTAAKSYCGMAAHGYPLSHGHFVHPQDQAHSQLKMTYLPPSPPTSEPGSPDRQKELLHNLTPPPSYAATIASKMAGHAPSHPTPASTRPPTTTGSMPVRYNRRTNPDLEKRRIHHCDFPGCKKVYTKSSHLKAHLRTHTGEKPYRCTWEGCDWRFARSDELTRHFRKHTGAKPFQCAVCSRSFSRSDHLALHMKRHQN", "length": 429, "header": "tr|A0A8M9P800-1|A0A8M9P800_DANRE Isoform 1 of Krueppel-like factor 5 OS=Danio rerio OX=7955 GN=klf5a PE=4 SV=1 CANONICAL=A0A8M9P800-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P800-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P800/entry#A0A8M9P800-1", "sequence": { "sequence": "MAATLLTMSAALAPGQDDFLSLLKPSLSDGFQQDSSLFCFEHKIPDSERGLSNDYSQAKLEMDKYLSPQPVVLPDLKKSRRESVSTMDQYFGDDHGSPYSINMNVYLPDIAYLRTGLCRAARHSVSNQVKTEPVTAPFSHPECPVSSSGPAPSALPDFTSIFNSNSTSGSGMDVVDDSAGVFVKQEMQGFDIPQDGPLFQLLNSELDVPDPTDPHAHSQMPTFHNLHLAAQQTAAKSYCGMAAHGYPLSHGHFVHPQDQAHSQLKMTYLPPSPPTSEPGSPDRQKELLHNLTPPPSYAATIASKMAGHAPSHPTPASTRPPTTTGSMPVRYNRRTNPDLEKRRIHHCDFPGCKKVYTKSSHLKAHLRTHTGEKPYRCTWEGCDWRFARSDELTRHFRKHTGAKPFQCAVCSRSFSRSDHLALHMKRHQN", "length": 429, "header": "tr|A0A8M9P800-1|A0A8M9P800_DANRE Isoform 1 of Krueppel-like factor 5 OS=Danio rerio OX=7955 GN=klf5a PE=4 SV=1 CANONICAL=A0A8M9P800-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 314, "start_aa": "Thr", "end_pos": 314, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr314", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100006043", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006043", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B8JL64-1", "protein_name": "Krueppel-like factor 5", "gene_name": "klf5b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDGYLPPQFHALSDHKKYCQDNTFTMDQGTPYSINMNVFLPDVTYLRTGMCRTVRSVGPQIKTEPIHSSFNYSSCHGTVAPTMTHQEYTNLYTPAPETGSNVYIKHETPSIEFQDVPLFQLLNSDLEPNVPGGHSCTDSHNATCPPMSTYNSIHPASSHGTERSICNMASNGYSLPAQFGQHPQKRAAYLPPSPPNSEPGSPDRRKELIQNLSPPPSYAASMASKMACLTPGPALSVQTQQVPAQYNRRSNPDLDKRRIHHCDVPGCKKVYTKSSHLKAHLRTHTGEKPYKCSWEGCDWRFARSDELTRHFRKHTGAKPFQCSVCSRCFSRSDHLALHMKRHQN", "length": 344 }, "evidence": [ { "id": "HGNC:6349", "url": "https://alliancegenome.org/gene/HGNC:6349#orthology", "database": "AGR" }, { "id": "MGI:1338056", "url": "https://alliancegenome.org/gene/MGI:1338056#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LSL7-1", "protein_name": "KLF transcription factor 5", "gene_name": "Klf5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTRVLTMSARLGPVPQPPAAQDEPVFAQLKPVLGAANPVRDAALFPGDDLKHAHHHPPAPPPAAGPRLPSEELVQTRCEMEKYLTPQLPPVPIISEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTQIKTEPVTIFSHQSESTAPPPPAPTQALPEFTSIFSSHQTTAPEVNNIFIKQELPIPDLHLSVPSQQGHLYQLLNTPDLDMPSSTNQTAVMDTLNVSMAGLNSHPSAVPQTSMKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPATLPVNSPNIQPVRYNRRSNPDLEKRRIHFCDYDGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCVVCNRSFSRSDHLALHMKRHQN", "length": 443 }, "evidence": [ { "id": "HGNC:6349", "url": "https://alliancegenome.org/gene/HGNC:6349#orthology", "database": "AGR" }, { "id": "MGI:1338056", "url": "https://alliancegenome.org/gene/MGI:1338056#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13887-1", "protein_name": "Krueppel-like factor 5", "gene_name": "KLF5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQAQPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPPAPTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMPSSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN", "length": 457 }, "evidence": [ { "id": "HGNC:6349", "url": "https://alliancegenome.org/gene/HGNC:6349#orthology", "database": "AGR" }, { "id": "MGI:1338056", "url": "https://alliancegenome.org/gene/MGI:1338056#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-167", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-167#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VZN4-1", "protein_name": "Dendritic arbor reduction protein 1", "gene_name": "dar1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHTDIIIGDQFAANNNYWVMQSPELDYRHELMGRLHKIEPADVELEVLAAAAAAANNNNNTSSNNNHSSNSSSNNSNGSQTPNGNNNSSLATGGHQHHQFHHHLHHHHSHQHHHQHHHLHQHHSHSLQSGESGASEAWPHLPAPSYASDVPHAQQQQLQPAGSPNSNSNGAYGCAPLYDGAPYEVALGYGGAVVASTGGATSSDKEYLYETKNKEALYADPLDDPYQRPVLWDDITTSIQNIDPENALMLSSSGSSNNNGSSNSSSNTGESATSQLPQVKMEAIDESLLETFSTPLLSPLEIKTEKQQRQQQHQHQQQQQQQQQQQQQHQQQHQQQYQQQHYQQHYQQQHLYQHHPSLALPGLPPAVDVVELQLQQQHQQQQHLQHNNSSSSSPKLATPGDNSGNTSSYQQQYASQLVSGSGGGYLNGSSSNSYGYSWHSSQSFHTKYQIHPPSAAASATASATATPTAQLGAQQQQQQQQQQQLQQLCPPAAPSTPSTSSSSISSSSASSASRHMFVPPLTPPSSDPGSPGSSMVAAAAAAAAQRRTTPPPPYQQGHVMGLINPPPTLQLLGGAATGSNNSCTTTLTTLTPASAIQQQQQQPQQQQVPQQQPPPTPRSSGGGRRGRHSHHQPGTAAHIASLMSVRTVRYNRRNNPELEKRRIHHCDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARSDELTRHYRKHTGAKPFKCIVCERSFARSDHLALHMKRHLPKNK", "length": 751 }, "evidence": [ { "id": "HGNC:6349", "url": "https://alliancegenome.org/gene/HGNC:6349#orthology", "database": "AGR" }, { "id": "MGI:1338056", "url": "https://alliancegenome.org/gene/MGI:1338056#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z0Z7-1", "protein_name": "Krueppel-like factor 5", "gene_name": "Klf5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTRVLTMSARLGPLPQPPAAQDEPVFAQLKPVLGAANPARDAALFSGDDLKHAHHHPPAPPPAAGPRLPSEELVQTRCEMEKYLTPQLPPVPIISEHKKYRRDSASVVDQFFTDTEGIPYSINMNVFLPDITHLRTGLYKSQRPCVTQIKTEPVTIFSHQSESTAPPPPPAPTQALPEFTSIFSSHQTTAPPQEVNNIFIKQELPIPDLHLSVPSQQGHLYQLLNTPDLDMPSSTNQTAVMDTLNVSMAGLNPHPSAVPQTSMKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPATLPVNSPTLPPVRYNRRSNPDLEKRRIHFCDYNGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCMVCQRSFSRSDHLALHMKRHQN", "length": 446 }, "evidence": [ { "id": "HGNC:6349", "url": "https://alliancegenome.org/gene/HGNC:6349#orthology", "database": "AGR" }, { "id": "MGI:1338056", "url": "https://alliancegenome.org/gene/MGI:1338056#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-167", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-167#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P800", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P800" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P800", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P800" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "digestive tract development", "id": "GO:0048565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048565", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P800", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P800" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P800", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P800" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 345, "end_pos": 374, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 314 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 165, "end_pos": 167 }, { "start_pos": 290, "end_pos": 292 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P803-1", "uniprot_ac": "A0A8M9P803", "uniprot_id": "A0A8M9P803_DANRE", "mass": { "chemical_mass": 25367.0, "monoisotopic_mass": 25367.0 }, "refseq": { "ac": "XP_021326897", "name": "uncharacterized protein si:ch211-113e8.11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326897" }, "gene_names": [ { "name": "si:ch211-113e8.11", "type": "recommended", "evidence": [ { "id": "A0A8M9P803", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P803" } ] }, { "name": "si:ch211-113e8.11", "type": "synonym", "evidence": [ { "id": "XP_021326897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326897" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch211-113e8.11", "type": "synonym", "evidence": [ { "id": "A0A8M9P803", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P803/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch211-113e8.11", "type": "synonym", "evidence": [ { "id": "XP_021326897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326897" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021326897.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326897" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P803", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P803" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-113e8.11", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P803", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-12", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-12", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P803", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P803", "database": "AlphaFoldDB", "categories": [] }, { "id": "569198", "url": "https://www.ncbi.nlm.nih.gov/gene/569198", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569198", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569198", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NGKRICW", "url": "https://omabrowser.org/oma/group/NGKRICW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PF00642", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00642", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021326897", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326897", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P803", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P803", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P803-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P803-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-12", "url": "https://zfin.org/ZDB-GENE-090313-12", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNSLVGYGLSSESEDEETGEDNPKGTFIKPESAVEQTKSRNFLLQSESPSSDSESDPENEDQQEAPQPFSKPSSTPSVRPYPQKLPPPPLGSGGALSSASSVFTNPFKEKAEESLNVLQKHVPLTLQARPTQIGGKRICVAYRKDGRCRFGSKCKFAHDSDLQSNLKVTSDSGPKDTNVTHKNDPLASGEEDKETDEEKDNEQRKKKRVGVNDSLIPPKRALKQYARLSHP", "length": 231, "header": "tr|A0A8M9P803-1|A0A8M9P803_DANRE Isoform 1 of Uncharacterized protein si:ch211-113e8.11 OS=Danio rerio OX=7955 GN=si:ch211-113e8.11 PE=1 SV=2 CANONICAL=A0A8M9P803-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P803-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P803/entry#A0A8M9P803-1", "sequence": 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"database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P803", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P803" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P803", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P803" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 161, "start_aa": "Ile", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 75 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 212, "end_pos": 214 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", 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"site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PIW3-1", "uniprot_ac": "A0A8M9PIW3", "uniprot_id": "A0A8M9PIW3_DANRE", "mass": { "chemical_mass": 87663.0, "monoisotopic_mass": 87663.0 }, "refseq": { "ac": "XP_021326898", "name": "uncharacterized protein zfp91 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326898" }, "gene_names": [ { "name": "zfp91", "type": "recommended", "evidence": [ { "id": "A0A8M9PIW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3" } ] }, { "name": "zfp91", "type": "synonym", "evidence": [ { "id": "XP_021326898", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326898" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase ZFP91", "type": "recommended", "evidence": [ { "id": "A0A8M9PIW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3/entry#names_and_taxonomy" } ] }, { "name": "2.3.2.27", "type": "synonym", "evidence": [ { "id": "A0A8M9PIW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3/entry#names_and_taxonomy" } ] }, { "name": "RING-type E3 ubiquitin transferase ZFP91", "type": "synonym", "evidence": [ { "id": "A0A8M9PIW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3/entry#names_and_taxonomy" } ] }, { "name": "Zinc finger protein 91 homolog", "type": "synonym", "evidence": [ { "id": "A0A8M9PIW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein zfp91 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021326898", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326898" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021326898.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326898", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326898" } ] }, { "annotation": "DNA-binding transcription factor. Also acts as an atypical E3 ubiquitin-protein ligase that mediates 'Lys-63'-linked ubiquitination of MAP3K14/NIK, leading to stabilize and activate MAP3K14/NIK. It thereby acts as an activator of the non-canonical NF-kappa-B2/NFKB2 pathway. May also play an important role in cell proliferation and/or anti-apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PX97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PX97#function" }, { "database": "UniProtKB", "id": "ARBA00094191", "url": "https://www.uniprot.org/uniprotkb/ARBA00094191#function" }, { "database": "UniProtKB", "id": "A0A8M9Q0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q0L6#function" }, { "database": "UniProtKB", "id": "A0AC58JR30", "url": "https://www.uniprot.org/uniprotkb/A0AC58JR30#function" }, { "database": "UniProtKB", "id": "A0AC58JR18", "url": "https://www.uniprot.org/uniprotkb/A0AC58JR18#function" }, { "database": "UniProtKB", "id": "A0AC58JR27", "url": "https://www.uniprot.org/uniprotkb/A0AC58JR27#function" }, { "database": "UniProtKB", "id": "A0A8M9P807", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P807#function" }, { "database": "UniProtKB", "id": "A0A8M9PPW7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPW7#function" }, { "database": "UniProtKB", "id": "A0A8M9PIW3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3#function" } ] } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "GC", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] }, { "disease_id": "DOID:9119", "recommended_name": { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells." }, "synonyms": [ { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "AML - acute Myeloid Leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "Leukemia, Myelocytic, acute", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloblastic leukaemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloblastic leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myelogenous leukaemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myelogenous leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloid leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia", "description": "Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections." }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML - acute myeloid leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML - acute myeloid leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "ANLL", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute Nonlymphocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute Nonlymphocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute granulocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute granulocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloblastic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelogenous leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelogenous leukemias", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukaemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute nonlymphocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute nonlymphocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "hematopoeitic - acute Myleogenous leukaemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "hematopoeitic - acute Myleogenous leukemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, reduced survival in, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, myelocytic, acute", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "myeloid leukemia, acute", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "myeloid leukemia, acute, M4/M4Eo subtype, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute non lymphoblastic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute non lymphoblastic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid", "description": "" }, { "id": "MIM:601626", "resource": "MIM", "url": "https://www.omim.org/entry/601626", "name": "Leukemia, acute myelogenous", "description": "Leukemia, acute myelogenous" } ], "unlinked_id_list": [], "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIW3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zfp91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-11", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PIW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PIW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "555616", "url": "https://www.ncbi.nlm.nih.gov/gene/555616", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:555616", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555616", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408:SF64", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408:SF64", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46179", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46179", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46179:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46179:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021326898", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326898", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P807", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P807", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P807-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P807-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIW3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPW7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PX97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PX97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PX97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PX97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q0L6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q0L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q0L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q0L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JR18", "url": "https://www.uniprot.org/uniprotkb/A0AC58JR18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JR18-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JR18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JR27", "url": "https://www.uniprot.org/uniprotkb/A0AC58JR27", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JR27-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JR27-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JR30", "url": "https://www.uniprot.org/uniprotkb/A0AC58JR30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JR30-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JR30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-11", "url": "https://zfin.org/ZDB-GENE-090313-11", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEPQLSSNKEETESETAIEKSAGQSTASSPCRASRGRGDGCFNTEVTCPPETNGAATSATGSGRVLRDRSTRTIPVWRQTDISEDLAEVSRDASGNRRRKAKCPRRRKSPAAAAASSDAGKDSGGDCDLLDEFEENKDALVNRAARGRRVQVRSGARTCRGSPRTVFKIEPEMDVDYVEANKAVEKTGTSVEKKEEESMDDDVVEEEECPFVDDPKDENYRPQSNRIPSVRRQDKHSTMTDSSSDSDEAESSSQIPHEGEETISSDEDVPFRDDLNDQSYDPKDFSKSKRRPHTRLKEKKDKPTVQETPTEQETEIKTEGGETTEEQTRAEVEEGAEPPRKRGRRRKDDKSPRLPKRRKKPPVQYVRCEMEGCGTVLAHPRYLQHHIKYQHLMKKKYVCPHPTCGRLFRLQKQLLRHAKHHTDQRDYICEFCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADATYQFSCSICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITTPAGVTTLLETNTGSGQTEQGVSETRGSSTVPAGQVAPVTHVGPVMVVDQNHPLHSMQVPVTLALSSTEENNTPLQQTSSHSLQMPLQFVSSPVSQQQQQQIQQHPLHPSVTSISQQATLVQQLPVQSYSQQSPIVHMAFRALPQQQLPMVSVAQQMPLQTTQSHQNQALPRPSSHHQAPNTPLLSQNLPKALSDCRSGLGFRSDPSSSSSTSTQSSITPSETRQVIWEADGTNENGAGDWVAGGEGEEQSITDSSGNQIQRVLLQ", "length": 792, "header": "tr|A0A8M9PIW3-1|A0A8M9PIW3_DANRE Isoform 1 of E3 ubiquitin-protein ligase ZFP91 OS=Danio rerio OX=7955 GN=zfp91 PE=3 SV=2 CANONICAL=A0A8M9PIW3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P807-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3/entry#A0A8M9P807-1", "sequence": { "sequence": "MEPQLSSNKEETESETAIEKSAGQSTASSPCRASRGRGDGCFNTEVTCPPETNGAATSATGSGRVLRDRSTRTIPVWRQTDISEDLAEVSRDASGNRRRKAKCPRRRKSPAAAAASSDAGKDSGGDCDLLDDVEKKEEESMDDDVVEEEECPFVDDPKDENYRPQSNSEGEETISSDEDVPFRDDLNDQSYDPKDFSKSKRRPHTRLKEKKDKPTVQETPTEQETEIKTEGGETTEEQTRAEVEEGAEPPRKRGRRRKDDKSPRLPKRRKKPPVQYVRCEMEGCGTVLAHPRYLQHHIKYQHLMKKKYVCPHPTCGRLFRLQKQLLRHAKHHTDQRDYICEFCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADATYQFSCSICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITTPAGVTTLLETNTGSGQTEQGVSETRGSSTVPAGQVAPVTHVGPVMVVDQNHPLHSMQVPVTLALSSTEENNTPLQQTSSHSLQMPLQFVSSPVSQQQQQQIQQHPLHPSVTSISQQATLVQQLPVQSYSQQSPIVHMAFRALPQQQLPMVSVAQQMPLQTTQSHQNQALPRPSSHHQAPNTPLLSQNLPKALSDCRSGLGFRSDPSSSSSTSTQSSITPSETRQVIWEADGTNENGAGDWVAGGEGEEQSITDSSGNQIQRVLLQ", "length": 703, "header": "tr|A0A8M9P807-1|A0A8M9PIW3_DANRE Computationally mapped isoform of E3 ubiquitin-protein ligase ZFP91 OS=Danio rerio OX=7955 GN=zfp91 PE=3 SV=2 CANONICAL=A0A8M9PIW3-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PIW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3/entry#A0A8M9PIW3-1", "sequence": { "sequence": "MEPQLSSNKEETESETAIEKSAGQSTASSPCRASRGRGDGCFNTEVTCPPETNGAATSATGSGRVLRDRSTRTIPVWRQTDISEDLAEVSRDASGNRRRKAKCPRRRKSPAAAAASSDAGKDSGGDCDLLDEFEENKDALVNRAARGRRVQVRSGARTCRGSPRTVFKIEPEMDVDYVEANKAVEKTGTSVEKKEEESMDDDVVEEEECPFVDDPKDENYRPQSNRIPSVRRQDKHSTMTDSSSDSDEAESSSQIPHEGEETISSDEDVPFRDDLNDQSYDPKDFSKSKRRPHTRLKEKKDKPTVQETPTEQETEIKTEGGETTEEQTRAEVEEGAEPPRKRGRRRKDDKSPRLPKRRKKPPVQYVRCEMEGCGTVLAHPRYLQHHIKYQHLMKKKYVCPHPTCGRLFRLQKQLLRHAKHHTDQRDYICEFCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADATYQFSCSICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITTPAGVTTLLETNTGSGQTEQGVSETRGSSTVPAGQVAPVTHVGPVMVVDQNHPLHSMQVPVTLALSSTEENNTPLQQTSSHSLQMPLQFVSSPVSQQQQQQIQQHPLHPSVTSISQQATLVQQLPVQSYSQQSPIVHMAFRALPQQQLPMVSVAQQMPLQTTQSHQNQALPRPSSHHQAPNTPLLSQNLPKALSDCRSGLGFRSDPSSSSSTSTQSSITPSETRQVIWEADGTNENGAGDWVAGGEGEEQSITDSSGNQIQRVLLQ", "length": 792, "header": "tr|A0A8M9PIW3-1|A0A8M9PIW3_DANRE Isoform 1 of E3 ubiquitin-protein ligase ZFP91 OS=Danio rerio OX=7955 GN=zfp91 PE=3 SV=2 CANONICAL=A0A8M9PIW3-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PPW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3/entry#A0A8M9PPW7-1", "sequence": { "sequence": "MEPQLSSNKEETESETAIEKSAGQSTASSPCRASRGRGDGCFNTEVTCPPETNGAATSATGSGRVLRDRSTRTIPVWRQTDISEDLAEVSRDASGNRRRKAKCPRRRKSPAAAAASSDAGKDSGGDCDLLDEFEENKDALVNRAARGRRVQVRSGARTCRGSPRTVFKIEPEMDVDYVEANKAVEKTGTSVEKKEEESMDDDVVEEEECPFVDDPKDENYRPQSNRIPSVRRQDKHSTMTDSSSDSDEAESSSQIPHEGEETISSDEDVPFRDDLNDQSYDPKDFSKSKRRPHTRLKEKKDKPTVQETPTEQETEIKTEGGETTEEQTRAEVEEGAEPPRKGRRRKDDKSPRLPKRRKKPPVQYVRCEMEGCGTVLAHPRYLQHHIKYQHLMKKKYVCPHPTCGRLFRLQKQLLRHAKHHTDQRDYICEFCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADATYQFSCSICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITTPAGVTTLLETNTGSGQTEQGVSETRGSSTVPAGQVAPVTHVGPVMVVDQNHPLHSMQVPVTLALSSTEENNTPLQQTSSHSLQMPLQFVSSPVSQQQQQQIQQHPLHPSVTSISQQATLVQQLPVQSYSQQSPIVHMAFRALPQQQLPMVSVAQQMPLQTTQSHQNQALPRPSSHHQAPNTPLLSQNLPKALSDCRSGLGFRSDPSSSSSTSTQSSITPSETRQVIWEADGTNENGAGDWVAGGEGEEQSITDSSGNQIQRVLLQ", "length": 791, "header": "tr|A0A8M9PPW7-1|A0A8M9PPW7_DANRE Computationally mapped isoform of E3 ubiquitin-protein ligase ZFP91 OS=Danio rerio OX=7955 GN=zfp91 PE=3 SV=2 CANONICAL=A0A8M9PIW3-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PX97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3/entry#A0A8M9PX97-1", "sequence": { "sequence": "MEPQLSSNKEETESETAIEKSAGQSTASSPCRASRGRGDGCFNTEVTCPPETNGAATSATGSGRVLRDRSTRTIPVWRQTDISEDLAEVSRDASGNRRRKAKCPRRRKSPAAAAASSDAGKDSGGDCDLLDDVEKKEEESMDDDVVEEEECPFVDDPKDENYRPQSNRIPSVRRQDKHSTMTDSSSDSDEAESSSQIPHEGEETISSDEDVPFRDDLNDQSYDPKDFSKSKRRPHTRLKEKKDKPTVQETPTEQETEIKTEGGETTEEQTRAEVEEGAEPPRKRGRRRKDDKSPRLPKRRKKPPVQYVRCEMEGCGTVLAHPRYLQHHIKYQHLMKKKYVCPHPTCGRLFRLQKQLLRHAKHHTDQRDYICEFCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADATYQFSCSICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITTPAGVTTLLETNTGSGQTEQGVSETRGSSTVPAGQVAPVTHVGPVMVVDQNHPLHSMQVPVTLALSSTEENNTPLQQTSSHSLQMPLQFVSSPVSQQQQQQIQQHPLHPSVTSISQQATLVQQLPVQSYSQQSPIVHMAFRALPQQQLPMVSVAQQMPLQTTQSHQNQALPRPSSHHQAPNTPLLSQNLPKALSDCRSGLGFRSDPSSSSSTSTQSSITPSETRQVIWEADGTNENGAGDWVAGGEGEEQSITDSSGNQIQRVLLQ", "length": 734, "header": "tr|A0A8M9PX97-1|A0A8M9PIW3_DANRE Computationally mapped isoform of E3 ubiquitin-protein ligase ZFP91 OS=Danio rerio OX=7955 GN=zfp91 PE=3 SV=2 CANONICAL=A0A8M9PIW3-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q0L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3/entry#A0A8M9Q0L6-1", "sequence": { "sequence": "MEPQLSSNKEETESETAIEKSAGQSTASSPCRASRGRGDGCFNTEVTCPPETNGAATSATGSGRVLRDRSTRTIPVWRQTDISEDLAEVSRDASGNRRRKAKCPRRRKSPAAAAASSDAGKDSGGDCDLLDEFEENKDALVNRAARGRRVQVRSGARTCRGSPRTVFKIEPEMDVDYVEANKAVEKTGTSVEKKEEESMDDDVVEEEECPFVDDPKDENYRPQSNSEGEETISSDEDVPFRDDLNDQSYDPKDFSKSKRRPHTRLKEKKDKPTVQETPTEQETEIKTEGGETTEEQTRAEVEEGAEPPRKRGRRRKDDKSPRLPKRRKKPPVQYVRCEMEGCGTVLAHPRYLQHHIKYQHLMKKKYVCPHPTCGRLFRLQKQLLRHAKHHTDQRDYICEFCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADATYQFSCSICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITTPAGVTTLLETNTGSGQTEQGVSETRGSSTVPAGQVAPVTHVGPVMVVDQNHPLHSMQVPVTLALSSTEENNTPLQQTSSHSLQMPLQFVSSPVSQQQQQQIQQHPLHPSVTSISQQATLVQQLPVQSYSQQSPIVHMAFRALPQQQLPMVSVAQQMPLQTTQSHQNQALPRPSSHHQAPNTPLLSQNLPKALSDCRSGLGFRSDPSSSSSTSTQSSITPSETRQVIWEADGTNENGAGDWVAGGEGEEQSITDSSGNQIQRVLLQ", "length": 761, "header": "tr|A0A8M9Q0L6-1|A0A8M9PIW3_DANRE Computationally mapped isoform of E3 ubiquitin-protein ligase ZFP91 OS=Danio rerio OX=7955 GN=zfp91 PE=3 SV=2 CANONICAL=A0A8M9PIW3-1" }, "locus": {} }, { "isoform_ac": "A0AC58JR18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3/entry#A0AC58JR18-1", "sequence": { "sequence": "MEPQLSSNKEETESETAIEKSAGQSTASSPCRASRGRGDGCFNTEVTCPPETNGAATSATGSGRVLRDRSTRTIPVWRQTDISEDLAEVSRDASGNRRRKAKCPRRRKSPAAAAASSDAGKDSGGDCDLLDDVEKKEEESMDDDVVEEEECPFVDDPKDENYRPQSNRIPSVRRQDKHSTMTDSSSDSDEAESSSQIPHEGEETISSDEDVPFRDDLNDQSYDPKDFSKSKRRPHTRLKEKKDKPTVQETPTEQETEIKTEGGETTEEQTRAEVEEGAEPPRKGRRRKDDKSPRLPKRRKKPPVQYVRCEMEGCGTVLAHPRYLQHHIKYQHLMKKKYVCPHPTCGRLFRLQKQLLRHAKHHTDQRDYICEFCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADATYQFSCSICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITTPAGVTTLLETNTGSGQTEQGVSETRGSSTVPAGQVAPVTHVGPVMVVDQNHPLHSMQVPVTLALSSTEENNTPLQQTSSHSLQMPLQFVSSPVSQQQQQQIQQHPLHPSVTSISQQATLVQQLPVQSYSQQSPIVHMAFRALPQQQLPMVSVAQQMPLQTTQSHQNQALPRPSSHHQAPNTPLLSQNLPKALSDCRSGLGFRSDPSSSSSTSTQSSITPSETRQVIWEADGTNENGAGDWVAGGEGEEQSITDSSGNQIQRVLLQ", "length": 733, "header": "tr|A0AC58JR18-1|A0AC58JR18_DANRE Computationally mapped isoform of E3 ubiquitin-protein ligase ZFP91 OS=Danio rerio OX=7955 GN=zfp91 PE=3 SV=1 CANONICAL=A0A8M9PIW3-1" }, "locus": {} }, { "isoform_ac": "A0AC58JR27-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3/entry#A0AC58JR27-1", "sequence": { "sequence": "MEPQLSSNKEETESETAIEKSAGQSTASSPCRASRGRGDGCFNTEVTCPPETNGAATSATGSGRVLRDRSTRTIPVWRQTDISEDLAEVSRDASGNRRRKAKCPRRRKSPAAAAASSDAGKDSGGDCDLLDDVEKKEEESMDDDVVEEEECPFVDDPKDENYRPQSNSEGEETISSDEDVPFRDDLNDQSYDPKDFSKSKRRPHTRLKEKKDKPTVQETPTEQETEIKTEGGETTEEQTRAEVEEGAEPPRKGRRRKDDKSPRLPKRRKKPPVQYVRCEMEGCGTVLAHPRYLQHHIKYQHLMKKKYVCPHPTCGRLFRLQKQLLRHAKHHTDQRDYICEFCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADATYQFSCSICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITTPAGVTTLLETNTGSGQTEQGVSETRGSSTVPAGQVAPVTHVGPVMVVDQNHPLHSMQVPVTLALSSTEENNTPLQQTSSHSLQMPLQFVSSPVSQQQQQQIQQHPLHPSVTSISQQATLVQQLPVQSYSQQSPIVHMAFRALPQQQLPMVSVAQQMPLQTTQSHQNQALPRPSSHHQAPNTPLLSQNLPKALSDCRSGLGFRSDPSSSSSTSTQSSITPSETRQVIWEADGTNENGAGDWVAGGEGEEQSITDSSGNQIQRVLLQ", "length": 702, "header": "tr|A0AC58JR27-1|A0AC58JR27_DANRE Computationally mapped isoform of E3 ubiquitin-protein ligase ZFP91 OS=Danio rerio OX=7955 GN=zfp91 PE=3 SV=1 CANONICAL=A0A8M9PIW3-1" }, "locus": {} }, { "isoform_ac": "A0AC58JR30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3/entry#A0AC58JR30-1", "sequence": { "sequence": "MEPQLSSNKEETESETAIEKSAGQSTASSPCRASRGRGDGCFNTEVTCPPETNGAATSATGSGRVLRDRSTRTIPVWRQTDISEDLAEVSRDASGNRRRKAKCPRRRKSPAAAAASSDAGKDSGGDCDLLDEFEENKDALVNRAARGRRVQVRSGARTCRGSPRTVFKIEPEMDVDYVEANKAVEKTGTSVEKKEEESMDDDVVEEEECPFVDDPKDENYRPQSNSEGEETISSDEDVPFRDDLNDQSYDPKDFSKSKRRPHTRLKEKKDKPTVQETPTEQETEIKTEGGETTEEQTRAEVEEGAEPPRKGRRRKDDKSPRLPKRRKKPPVQYVRCEMEGCGTVLAHPRYLQHHIKYQHLMKKKYVCPHPTCGRLFRLQKQLLRHAKHHTDQRDYICEFCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADATYQFSCSICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITTPAGVTTLLETNTGSGQTEQGVSETRGSSTVPAGQVAPVTHVGPVMVVDQNHPLHSMQVPVTLALSSTEENNTPLQQTSSHSLQMPLQFVSSPVSQQQQQQIQQHPLHPSVTSISQQATLVQQLPVQSYSQQSPIVHMAFRALPQQQLPMVSVAQQMPLQTTQSHQNQALPRPSSHHQAPNTPLLSQNLPKALSDCRSGLGFRSDPSSSSSTSTQSSITPSETRQVIWEADGTNENGAGDWVAGGEGEEQSITDSSGNQIQRVLLQ", "length": 760, "header": "tr|A0AC58JR30-1|A0AC58JR30_DANRE Computationally mapped isoform of E3 ubiquitin-protein ligase ZFP91 OS=Danio rerio OX=7955 GN=zfp91 PE=3 SV=1 CANONICAL=A0A8M9PIW3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 403, "start_aa": "Thr", "end_pos": 403, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr403", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:555616", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555616", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MAJ8-1", "protein_name": "E3 ubiquitin-protein ligase ZFP91", "gene_name": "Zfp91", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGETEEPRSPEQQDQEGGPAAAADAASDELRSGVAAAAKPAETASSRVLRGGRDRGRTAAAAAAAAVSRRRKAEYPRRRRSSPSNRPPDGHGHQPAAAKPPSPAQGKKSPRLQCIEKITTDKDPKEEKEDDSVLPQEVSITATRPSRSWRSSSRTSISRLRDSENTRSSRSKTGSLQLVCKTEPITDQLDYDVPEEHQSPSGISSDEEEEEEEMLISEEEIPFKDDPRDETYKPHLERETPKPRRKSGKVKEEKEKKEIKVEVEVEVKEEENEIREDEEPPRKRGRRRKDDKSPRLPKRRKKPPIQYVRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKYVCPHPSCGRLFRLQKQLLRHAKHHTDQRDYICEYCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADSFYQFSCNICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITSTDILGTNPEPLTQPADSQGLPLLPEPLGNSTSGECLLLEAEGMSKSYCSGTERVSLMADGKIFVGSGSSGGTEGLVMNSDILGATTEVLIEDTDSTGP", "length": 568 }, "evidence": [ { "id": "RGD:628736", "url": "https://alliancegenome.org/gene/RGD:628736#orthology", "database": "AGR" }, { "id": "MGI:104854", "url": "https://alliancegenome.org/gene/MGI:104854#orthology", "database": "AGR" }, { "id": "HGNC:14983", "url": "https://alliancegenome.org/gene/HGNC:14983#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-11#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q62511-1", "protein_name": "E3 ubiquitin-protein ligase ZFP91", "gene_name": "Zfp91", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGETEEPRSPEQQDQEGGPAAAADAASEELRPGAAAAPAAPAETASSRVLRGGRDRGRTAAAAAAAAAAVSRRRKAEYPRRRRSSPSNRPPDGPGHQPAAAKPPSPAQGKKSPRLQCIEKLTTDKDPKEEKEDDSVLPQEVSITTTRASRSWRSSSRTSISRLRDSENTRSSRSKTGSLQLVCKTEPITDQLDYDVPEEHQSPGGISSDEEEEEEEEMLISEEEIPFKDDPRDETYKPHLERETPKPRRKSGKVKEEKEKKEIKVEVEVEVKEEENEIREDEEPPRKRGRRRKDDKSPRLPKRRKKPPIQYVRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKYVCPHPSCGRLFRLQKQLLRHAKHHTDQRDYICEYCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADSFYQFSCNICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITSTDILGTNPEPLTQPADGQGLPLLPEPLGNSTAGECLLLEAEGMSKSYCSGTERVSLMADGKIFVGSGSSGGTEGLVMNSDILGATTEVLIEDTDSTGP", "length": 572 }, "evidence": [ { "id": "RGD:628736", "url": "https://alliancegenome.org/gene/RGD:628736#orthology", "database": "AGR" }, { "id": "MGI:104854", "url": "https://alliancegenome.org/gene/MGI:104854#orthology", "database": "AGR" }, { "id": "HGNC:14983", "url": "https://alliancegenome.org/gene/HGNC:14983#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-11#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JP5-1", "protein_name": "E3 ubiquitin-protein ligase ZFP91", "gene_name": "ZFP91", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGETEEPRPPEQQDQEGGEAAKAAPEEPQQRPPEAVAAAPAGTTSSRVLRGGRDRGRAAAAAAAAAVSRRRKAEYPRRRRSSPSARPPDVPGQQPQAAKSPSPVQGKKSPRLLCIEKVTTDKDPKEEKEEEDDSALPQEVSIAASRPSRGWRSSRTSVSRHRDTENTRSSRSKTGSLQLICKSEPNTDQLDYDVGEEHQSPGGISSEEEEEEEEEMLISEEEIPFKDDPRDETYKPHLERETPKPRRKSGKVKEEKEKKEIKVEVEVEVKEEENEIREDEEPPRKRGRRRKDDKSPRLPKRRKKPPIQYVRCEMEGCGTVLAHPRYLQHHIKYQHLLKKKYVCPHPSCGRLFRLQKQLLRHAKHHTDQRDYICEYCARAFKSSHNLAVHRMIHTGEKPLQCEICGFTCRQKASLNWHMKKHDADSFYQFSCNICGKKFEKKDSVVAHKAKSHPEVLIAEALAANAGALITSTDILGTNPESLTQPSDGQGLPLLPEPLGNSTSGECLLLEAEGMSKSYCSGTERVSLMADGKIFVGSGSSGGTEGLVMNSDILGATTEVLIEDSDSAGP", "length": 570 }, "evidence": [ { "id": "RGD:628736", "url": "https://alliancegenome.org/gene/RGD:628736#orthology", "database": "AGR" }, { "id": "MGI:104854", "url": "https://alliancegenome.org/gene/MGI:104854#orthology", "database": "AGR" }, { "id": "HGNC:14983", "url": "https://alliancegenome.org/gene/HGNC:14983#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-11#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIW3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIW3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIW3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of primary metabolic process", "id": "GO:0080090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0080090", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIW3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3" } ], "pmid": "" }, { "name": "regulation of macromolecule metabolic process", "id": "GO:0060255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060255", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIW3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PIW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIW3" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 397, "end_pos": 426, "start_aa": "Tyr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.3.2.27", "ec_name": "S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.", "evidence": [ { "id": "2.3.2.27", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.3.2.27" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 403 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 597, "end_pos": 599 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PJM9-1", "uniprot_ac": "A0A8M9PJM9", "uniprot_id": "A0A8M9PJM9_DANRE", "mass": { "chemical_mass": 47757.0, "monoisotopic_mass": 47757.0 }, "refseq": { "ac": "XP_021322431", "name": "carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322431" }, "gene_names": [ { "name": "nos1apb", "type": "recommended", "evidence": [ { "id": "A0A8M9PJM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9" } ] }, { "name": "nos1apb", "type": "synonym", "evidence": [ { "id": "XP_021322431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322431" } ] } ], "protein_names": [ { "name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PJM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9/entry#names_and_taxonomy" } ] }, { "name": "C-terminal PDZ ligand of neuronal nitric oxide synthase protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PJM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9/entry#names_and_taxonomy" } ] }, { "name": "Nitric oxide synthase 1 adaptor protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PJM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9/entry#names_and_taxonomy" } ] }, { "name": "carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322431", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322431" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322431" } ] }, { "annotation": "Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4. In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P812", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P812#function" }, { "database": "UniProtKB", "id": "ARBA00054402", "url": "https://www.uniprot.org/uniprotkb/ARBA00054402#function" }, { "database": "UniProtKB", "id": "A0A8M9PJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9#function" }, { "database": "UniProtKB", "id": "U3JAK8", "url": "https://www.uniprot.org/uniprotkb/U3JAK8#function" }, { "database": "UniProtKB", "id": "A0AC58HB50", "url": "https://www.uniprot.org/uniprotkb/A0AC58HB50#function" } ] } ], "disease": [ { "disease_id": "DOID:0112268", "recommended_name": { "id": "DOID:0112268", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112268", "name": "nephrotic syndrome type 22", "description": "A familial nephrotic syndrome characterized by onset of progressive kidney dysfunction in infancy, edema, hypoproteinemia, proteinuria, microscopic hematuria, effacement of the podocyte foot processes, glomerulosclerosis, and thickening of the glomerular basement membrane that has_material_basis_in homozygous or compound heterozygous mutation in the NOS1AP gene on chromosome 1q23.3." }, "synonyms": [ { "id": "DOID:0112268", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112268", "name": "NPHS22", "description": "" }, { "id": "MONDO:0030895", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030895", "name": "nephrotic syndrome, type 22", "description": "" }, { "id": "MONDO:0030895", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030895", "name": "NPHS22", "description": "" }, { "id": "MONDO:0030895", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030895", "name": "nephrotic syndrome, type 22", "description": "" }, { "id": "MIM:619155", "resource": "MIM", "url": "https://www.omim.org/entry/619155", "name": "Nephrotic syndrome 22", "description": "Nephrotic syndrome 22" } ], "unlinked_id_list": [], "evidence": [ { "id": "0112268", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112268" } ] }, { "disease_id": "DOID:11723", "recommended_name": { "id": "DOID:11723", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11723", "name": "Duchenne muscular dystrophy", "description": "A muscular dystrophy that has_material_basis_in X-linked mutations in the DMD gene found on the X chromosome. It is characterized by rapidly progressing muscle weakness and muscle atrophy initially involving the lower extremities and eventually affecting the whole body. It affects males whereas females can be carriers. The symptoms start before the age of six and may appear at infancy." }, "synonyms": [ { "id": "DOID:11723", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11723", "name": "Muscular dystrophy, Duchenne", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "Duchenne muscular dystrophy", "description": "Duchenne muscular dystrophy (DMD) is a neuromuscular disease characterized by rapidly progressive muscle weakness and wasting due to degeneration of skeletal, smooth and cardiac muscle." }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "DMD", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "Duchenne muscular dystrophy", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "Duchenne muscular dystrophy, X-linked recessive", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "severe dystrophinopathy, Duchenne type", "description": "" }, { "id": "MONDO:0010679", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010679", "name": "muscular dystrophy, Duchenne type", "description": "" }, { "id": "MIM:310200", "resource": "MIM", "url": "https://www.omim.org/entry/310200", "name": "Duchenne muscular dystrophy", "description": "Duchenne muscular dystrophy" } ], "unlinked_id_list": [], "evidence": [ { "id": "11723", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11723" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nos1apb", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100824-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100824-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PJM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PJM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000058701", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000058701", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100331166", "url": "https://www.ncbi.nlm.nih.gov/gene/100331166", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100331166", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331166", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QLSVEAC", "url": "https://omabrowser.org/oma/group/QLSVEAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PJM9", "url": "https://www.orthodb.org/?gene=A0A8M9PJM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "U3JAK8", "url": "https://www.orthodb.org/?gene=U3JAK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232:SF76", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232:SF76", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322431", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322431", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P812", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P812", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P812-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P812-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HB50", "url": "https://www.uniprot.org/uniprotkb/A0AC58HB50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HB50-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HB50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "U3JAK8", "url": "https://www.uniprot.org/uniprotkb/U3JAK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "U3JAK8-1", "url": "https://www.uniprot.org/uniprotkb/U3JAK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100824-1", "url": "https://zfin.org/ZDB-GENE-100824-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLEKCKYNLVDDSMDQRIPADNEGQFQHGLTFEVKFIGSLDIVRPKSRIEILAAMRRIRYEFKIKNIKKKKVSLIVSVDGVKVVLRKKKKVKFEYSWDESPVTLAQDPIFRIFYVSHDSQDLKIFSYIARDKKSNVFRCNVFKSKRKSQAMRIVRTVGQAFEVCHKQSLDNADAWLVKGEEERSKDEAVAAGSSTERAGDADPETDEKVEEESKSPLSSPLSVSHQVQLLQRQFQQQEQRSHAASAQVVLLQQQLSVETNARTEAQARVQQLLQQNTELLQHLSLLVKHVQELELRTQPHKNSPLGSQDSLLEIALRANMPAVSREPKPNPLLSAQRSFPLSNSLVRLDGFHFFTGASEQEKKPEQDRDSGRGQDEDQSGGSSPPENQFLSALDTPGFRESGIASGYESNTDESDDRDSWGQ", "length": 422, "header": "tr|A0A8M9PJM9-1|A0A8M9PJM9_DANRE Isoform 1 of Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Danio rerio OX=7955 GN=nos1apb PE=4 SV=1 CANONICAL=A0A8M9PJM9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P812-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9/entry#A0A8M9P812-1", "sequence": { "sequence": "MLEKCKYNLVDDSMDQRIPADNEGQFQHGLTFEVKFIGSLDIVRPKSRIEILAAMRRIRYEFKIKNIKKKKVSLIVSVDGVKVVLRKKKKVKFEYSWDESPVTLAQDPIFRIFYVSHDSQDLKIFSYIARDKKSNVFRCNVFKSKRKSQAMRIVRTVGQAFEVCHKQSLDNADAWLVKGEEERSKDEAVAAGSSTERAGDADPETDEKVEEESKSPLSSPLSVSHQVQLLQRQFQQQEQRSHAASAQVVLLQQQLSVETNARTEAQARVQQLLQQNTELLQHLSLLVKHVQELELRTQPHKNSPLGSQDSLLEIALRANMPAVSREPKPNPLLSAQRSFPLSNSLVRLDGFHFFTGASEQEKKPEQDRDSGRGQDEDQSGGSSPPENQFLSALDTPGFRESGIASGFHVGPLMIIAGSRL", "length": 420, "header": "tr|A0A8M9P812-1|A0A8M9PJM9_DANRE Computationally mapped isoform of Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Danio rerio OX=7955 GN=nos1apb PE=4 SV=1 CANONICAL=A0A8M9PJM9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PJM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9/entry#A0A8M9PJM9-1", "sequence": { "sequence": "MLEKCKYNLVDDSMDQRIPADNEGQFQHGLTFEVKFIGSLDIVRPKSRIEILAAMRRIRYEFKIKNIKKKKVSLIVSVDGVKVVLRKKKKVKFEYSWDESPVTLAQDPIFRIFYVSHDSQDLKIFSYIARDKKSNVFRCNVFKSKRKSQAMRIVRTVGQAFEVCHKQSLDNADAWLVKGEEERSKDEAVAAGSSTERAGDADPETDEKVEEESKSPLSSPLSVSHQVQLLQRQFQQQEQRSHAASAQVVLLQQQLSVETNARTEAQARVQQLLQQNTELLQHLSLLVKHVQELELRTQPHKNSPLGSQDSLLEIALRANMPAVSREPKPNPLLSAQRSFPLSNSLVRLDGFHFFTGASEQEKKPEQDRDSGRGQDEDQSGGSSPPENQFLSALDTPGFRESGIASGYESNTDESDDRDSWGQ", "length": 422, "header": "tr|A0A8M9PJM9-1|A0A8M9PJM9_DANRE Isoform 1 of Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Danio rerio OX=7955 GN=nos1apb PE=4 SV=1 CANONICAL=A0A8M9PJM9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HB50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9/entry#A0AC58HB50-1", "sequence": { "sequence": "MLEKCKYNLVDDSMDQRIPADNEGQFQHGLTFEVKFIGSLDIVRPKSRIEILAAMRRIRYEFKIKNIKKKKVSLIVSVDGVKVVLRKKKKKFEYSWDESPVTLAQDPIFRIFYVSHDSQDLKIFSYIARDKKSNVFRCNVFKSKRKSQAMRIVRTVGQAFEVCHKQSLDNADAWLVKGEEERSKDEAVAAGSSTERAGDADPETDEKVEEESKSPLSSPLSVSHQVQLLQRQFQQQEQRSHAASAQVVLLQQQLSVETNARTEAQARVQQLLQQNTELLQHLSLLVKHVQELELRTQPHKNSPLGSQDSLLEIALRANMPAVSREPKPNPLLSAQRSFPLSNSLVRLDGFHFFTGASEQEKKPEQDRDSGRGQDEDQSGGSSPPENQFLSALDTPGFRESGIASGFHVGPLMIIAGSRL", "length": 419, "header": "tr|A0AC58HB50-1|A0AC58HB50_DANRE Computationally mapped isoform of Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Danio rerio OX=7955 GN=nos1apb PE=4 SV=1 CANONICAL=A0A8M9PJM9-1" }, "locus": {} }, { "isoform_ac": "U3JAK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9/entry#U3JAK8-1", "sequence": { "sequence": "MLEKCKYNLVDDSMDQRIPADNEGQFQHGLTFEVKFIGSLDIVRPKSRIEILAAMRRIRYEFKIKNIKKKKVSLIVSVDGVKVVLRKKKKKFEYSWDESPVTLAQDPIFRIFYVSHDSQDLKIFSYIARDKKSNVFRCNVFKSKRKSQAMRIVRTVGQAFEVCHKQSLDNADAWLVKGEEERSKDEAVAAGSSTERAGDADPETDEKVEEESKSPLSSPLSVSHQVQLLQRQFQQQEQRSHAASAQVVLLQQQLSVETNARTEAQARVQQLLQQNTELLQHLSLLVKHVQELELRTQPHKNSPLGSQDSLLEIALRANMPAVSREPKPNPLLSAQRSFPLSNSLVRLDGFHFFTGASEQEKKPEQDRDSGRGQDEDQSGGSSPPENQFLSALDTPGFRESGIASGYESNTDESDDRDSWGQ", "length": 421, "header": "tr|U3JAK8-1|A0A8M9PJM9_DANRE Computationally mapped isoform of Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Danio rerio OX=7955 GN=nos1apb PE=4 SV=1 CANONICAL=A0A8M9PJM9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100331166", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331166", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9QB59-1", "protein_name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "gene_name": "nos1apa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPAKTKYNLVDDGHDLRIPLHNEEAFQHGINFEAKYIGSLDVARPNSRVEIVAAMRRIRYEFKVKNIKKKKVNIIVSVDGVKVALRKKKKKKEWTWDESKMMVMQDPIYRIFYVSHDSQDLKIFSYIARDGQSNVFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGDADKTCTDSGVAGRELTGAEKPAADETDIDAEELPLPDSTMDEFSRGVTDLDAAKKDEDVSKDKKPSEEPVILLASPKLLLPSGSDLPSSTPLSVHHQLQLLQQQLTQQQQQTQVAVAQVHLLKDQLSAEAAARIEAQARVHQLLLQNKDLLQHISLLVKQIQELELKLAGQGSMGSQDSLLEITFRANVPPVLCDPSTPRPEDSILPPLNDGTQLSLPLCSPIGRDQGLIKFECFRFLPGPPHQQEEDSPDTPSQDVSSSSRDELLGSLELLRFRESGIASEYESNTDESDESWGLQDESSLRLLNVLNKHIPSDCLDDEIAV", "length": 505 }, "evidence": [ { "id": "HGNC:16859", "url": "https://alliancegenome.org/gene/HGNC:16859#orthology", "database": "AGR" }, { "id": "MGI:1917979", "url": "https://alliancegenome.org/gene/MGI:1917979#orthology", "database": "AGR" }, { "id": "FB:FBgn0261555", "url": "https://alliancegenome.org/gene/FB:FBgn0261555#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O54960-1", "protein_name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "gene_name": "Nos1ap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSKTKYNLVDDGHDLRIPLHNEDAFQHGISFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSDGSGDPGRQLTGAERVSTATAEETDIDAVEVPLPGNDILEFSRGVTDLDAIGKDGGSHIDTTVSPHPQEPMLAASPRMLLPSSSSSKPPGLGTGTPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQSTMGSQDSLLEITFRSGALPVLCESTTPKPEDLHSPLLGAGLADFAHPVGSPLGRRDCLVKLECFRFLPAEDNQPMAQGEPLLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDSLDDEIAV", "length": 503 }, "evidence": [ { "id": "HGNC:16859", "url": "https://alliancegenome.org/gene/HGNC:16859#orthology", "database": "AGR" }, { "id": "MGI:1917979", "url": "https://alliancegenome.org/gene/MGI:1917979#orthology", "database": "AGR" }, { "id": "FB:FBgn0261555", "url": "https://alliancegenome.org/gene/FB:FBgn0261555#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75052-1", "protein_name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "gene_name": "NOS1AP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLGRRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDGLDDEIAV", "length": 506 }, "evidence": [ { "id": "HGNC:16859", "url": "https://alliancegenome.org/gene/HGNC:16859#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100824-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100824-1#orthology", "database": "AGR" }, { "id": "MGI:1917979", "url": "https://alliancegenome.org/gene/MGI:1917979#orthology", "database": "AGR" }, { "id": "FB:FBgn0261555", "url": "https://alliancegenome.org/gene/FB:FBgn0261555#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8SXX4-1", "protein_name": "Capon-like protein", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPSTPYDLVQDDQDLRVPLHAEQAFFHGITFQAKFVGWEEVPRPNTRAEIVQAMRRIRYECKVQNLKKRKVTIHISVNGVRVVLKKRRRKKKNWTNDPEDIELLNHPIYRIFYVSHDSSDLKIFSYIARDASTDTFKCSVFKSHKKSQAMRIVRTVGQAFEVCHKFNLHKNSLEPNDERSDISSSELLDVEQISEQQLSEDGERGGGDNETPKKEHLAITPDLNHTQPQRPNHLDIMPSHSSLRKSNSLLCDVDDKSPGSPSSPRSEITQLKDQLEAQALQTRQALGQLMLVREQLISETNARIEAQARTQQLLQQNRELLEHLASLGAYNEQQTAGLTSANIGMAPQQSQLQMLLQATSNNNNLATINQQISNLGSINQQLTSLSHQLSGLNQQSQHLQNLQQQQQQQQQQQQQQTQAAPTAATPPPAAGGSSPYPSMSALQSISNQLQQQQQQQQQDALSKDLFQVNQELLNRLQALNLNANPGQSQPTPSATAHNSFFYVNPLSCTPATPNNNAGGAGGFNFLTSPAATGTLTPSPLGTMNRNSFAGSSSLNEDIRLSIEQNLNNLEEQLKAAVSNGNLAGLACGGSTSTRDTSRSSSTLDSPSSPRLRSSNNNISPGSSNGNQNHNNNSNSNSSSSRETRFNTVLLRVTDEAGHQRKLSATPSFITRSTSEKVPNRSQMMSQVQRTTWARHTTK", "length": 698 }, "evidence": [ { "id": "HGNC:16859", "url": "https://alliancegenome.org/gene/HGNC:16859#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100824-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100824-1#orthology", "database": "AGR" }, { "id": "MGI:1917979", "url": "https://alliancegenome.org/gene/MGI:1917979#orthology", "database": "AGR" }, { "id": "FB:FBgn0261555", "url": "https://alliancegenome.org/gene/FB:FBgn0261555#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9D3A8-1", "protein_name": "Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein", "gene_name": "Nos1ap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSKTKYNLVDDGHDLRIPLHNEDAFQHGISFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSDGSGDPGRQLTGAERVSTAAAEETDIDAVEVPLPGNDILEFSRGVTDLDAVGKDGGSHIDSTVSPHPQEPMLTASPRMLLPSSSSKPPGLGTGTPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNTMGSQDSLLEITFRSGALPVLCESTTPKPEDLHSPLLGAGLADFAHPAGSPLGRHDCLVKLECFRFLPPEDTQPMMAQGEPLLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDSLDDEIAV", "length": 503 }, "evidence": [ { "id": "HGNC:16859", "url": "https://alliancegenome.org/gene/HGNC:16859#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100824-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100824-1#orthology", "database": "AGR" }, { "id": "MGI:1917979", "url": "https://alliancegenome.org/gene/MGI:1917979#orthology", "database": "AGR" }, { "id": "FB:FBgn0261555", "url": "https://alliancegenome.org/gene/FB:FBgn0261555#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nitric-oxide synthase binding", "id": "GO:0050998", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050998", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJM9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PJM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM9" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 174, "start_aa": "Gly", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P842-1", "uniprot_ac": "A0A8M9P842", "uniprot_id": "A0A8M9P842_DANRE", "mass": { "chemical_mass": 64715.0, "monoisotopic_mass": 64715.0 }, "refseq": { "ac": "XP_021322483", "name": "endoribonuclease ZC3H12A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322483" }, "gene_names": [ { "name": "zc3h12aa", "type": "recommended", "evidence": [ { "id": "A0A8M9P842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842" } ] }, { "name": "zc3h12aa", "type": "synonym", "evidence": [ { "id": "XP_021322483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322483" } ] } ], "protein_names": [ { "name": "Endoribonuclease ZC3H12A", "type": "synonym", "evidence": [ { "id": "A0A8M9P842", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842/entry#names_and_taxonomy" } ] }, { "name": "endoribonuclease ZC3H12A", "type": "synonym", "evidence": [ { "id": "XP_021322483", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322483" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322483", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322483" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P842", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zc3h12aa", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110411-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-6", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P842", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P842", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18729", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18729", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "798235", "url": "https://www.ncbi.nlm.nih.gov/gene/798235", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040546", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040546", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:798235", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798235", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P842", "url": "https://www.orthodb.org/?gene=A0A8M9P842", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12876", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12876", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12876:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12876:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11977", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11977", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322483", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322483", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P842", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P842-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110411-6", "url": "https://zfin.org/ZDB-GENE-110411-6", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MQSRCFHQPTGLGQDSHDLLNLQMKVDFFRKLGYSPQEVKAALRKLGLGTDTNAVLGELVRSGAKAVPPSVSNSDDGGSGSSHRGGGSSRGQGSTLDDATEAESDLKPIVIDGSNVAMSHGNKEVFSCRGIELAVNYFLDRGHRNITVFVPSWRKEQPRPDVPISDQHILGELERKKFLVFTPSRRVGGKRVVCYDDRFIVKLAHDLDGIIVSNDTYRDLQSERPEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPNLDNFLRKKAMLIDHKRQLCPYGKKCTYGIKCKFYHPERTNQSQRSLADELRENARLSGSKEDCRVSGSLRGVYPRNDPGSCSPSLEQELEKKLSLEPESSDSRDVLLHYWDDIMSMKKPLNTAPVGQYSALGDRTSLHAPYSKNPSIFSSDSGLGSYESQFSEQSQSFDELHRIRSGHPPMPGNPAVPAGGHYYNNISHFSSLQPNYTAYSSLPLPNPVQSYSLPACGGWSYPYYLTQATGLAEPLTSRSSQSAGVYGSQQHSAMTQSNAFQEEREEVRKKLYAIFNPRHVNKVMDMFPQLKDAQQLAAEVLKLKSSGEFF", "length": 579, "header": "tr|A0A8M9P842-1|A0A8M9P842_DANRE Isoform 1 of Endoribonuclease ZC3H12A OS=Danio rerio OX=7955 GN=zc3h12aa PE=3 SV=1 CANONICAL=A0A8M9P842-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P842-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842/entry#A0A8M9P842-1", "sequence": { "sequence": "MQSRCFHQPTGLGQDSHDLLNLQMKVDFFRKLGYSPQEVKAALRKLGLGTDTNAVLGELVRSGAKAVPPSVSNSDDGGSGSSHRGGGSSRGQGSTLDDATEAESDLKPIVIDGSNVAMSHGNKEVFSCRGIELAVNYFLDRGHRNITVFVPSWRKEQPRPDVPISDQHILGELERKKFLVFTPSRRVGGKRVVCYDDRFIVKLAHDLDGIIVSNDTYRDLQSERPEWKRFIEERLLMYSFVNDKFMPPDDPLGRHGPNLDNFLRKKAMLIDHKRQLCPYGKKCTYGIKCKFYHPERTNQSQRSLADELRENARLSGSKEDCRVSGSLRGVYPRNDPGSCSPSLEQELEKKLSLEPESSDSRDVLLHYWDDIMSMKKPLNTAPVGQYSALGDRTSLHAPYSKNPSIFSSDSGLGSYESQFSEQSQSFDELHRIRSGHPPMPGNPAVPAGGHYYNNISHFSSLQPNYTAYSSLPLPNPVQSYSLPACGGWSYPYYLTQATGLAEPLTSRSSQSAGVYGSQQHSAMTQSNAFQEEREEVRKKLYAIFNPRHVNKVMDMFPQLKDAQQLAAEVLKLKSSGEFF", "length": 579, "header": "tr|A0A8M9P842-1|A0A8M9P842_DANRE Isoform 1 of Endoribonuclease ZC3H12A OS=Danio rerio OX=7955 GN=zc3h12aa PE=3 SV=1 CANONICAL=A0A8M9P842-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:798235", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798235", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P842", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P842", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P842", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P842", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P842", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P842", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842" } ], "pmid": "" }, { "name": "cytoplasmic ribonucleoprotein granule", "id": "GO:0036464", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036464", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P842", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "post-transcriptional regulation of gene expression", "id": "GO:0010608", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010608", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P842", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842" } ], "pmid": "" }, { "name": "3'-UTR-mediated mRNA destabilization", "id": "GO:0061158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061158", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P842", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P842" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 464, "end_pos": 466, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326967", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326967" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P853", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P853" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438586", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P853", "locus": {} } ], "crossref": [ { "id": "A0A8M9P853", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P853", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438586", "url": "https://www.ncbi.nlm.nih.gov/gene/110438586", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001660", "url": 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"field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P861-1", "uniprot_ac": "A0A8M9P861", "uniprot_id": "A0A8M9P861_DANRE", "mass": { "chemical_mass": 93012.0, "monoisotopic_mass": 93012.0 }, "refseq": { "ac": "XP_021326982", "name": "zinc finger CCHC domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326982" }, "gene_names": [ { "name": "zcchc2", "type": "recommended", "evidence": [ { "id": "A0A8M9P861", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P861" } ] }, { "name": "zcchc2", "type": "synonym", "evidence": [ { "id": "XP_021326982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326982" } ] } ], "protein_names": [ { "name": "Zinc finger CCHC domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P861", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P861/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCHC domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021326982", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326982" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021326982.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326982" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P861", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P861" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zcchc2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P861", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-269", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-269", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P861", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P861", "database": "AlphaFoldDB", "categories": [] }, { "id": "564789", "url": "https://www.ncbi.nlm.nih.gov/gene/564789", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036875", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036875", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042793", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042793", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564789", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564789", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR46939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46939:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46939:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00098", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00098", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25479", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25479", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26034", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26034", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021326982", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326982", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P861", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P861", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P861-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P861-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJ40", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJ40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HXR2", "url": "https://www.uniprot.org/uniprotkb/A0AC58HXR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HXR2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HXR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-269", "url": "https://zfin.org/ZDB-GENE-070912-269", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMKMKLRAAGGENYRCDLNSVNGADRESGIGAAQLDKEAVFEWFGLQLNPAGRVELLCGLLHMCQPLELRFLGACLEDLARRDFTVLRDFEIRANSPADLEGLVDVSDPVVLSKLLVYLSLLGSKSRECACILFRTLSRMDVGMYGALPEPETVDQLRLLFTMGSLHPAFSFYQREELRAQLDRLQRWSQFSRPGFLCPHREDDGDWTLCSNANPHLSSTSQREVVHIEKIILKEISVGGDGRHYSFEVKWSDSSSSAVTKSHRELEDFLLKLPKEQSPGGFEKGIVKLLSRGDQCESRDLERNLREKFLSLSQDVLRRCDISRFFLSDASVLPCSHCTSAPVARIHQPERGFSEDCSETSSLEEDVEAYNIRAAGLSNQRSECQRRGNCEQNGERVWKKENELEQNCTNDRRIFTAGQKNKGRSAGKRDRVRRVTAVKTSNGIQKPSAALMINQAACKDAGRDRYGDTSSESSNSVPSSPVHQKSLEDQDTESQSDNSAQEPTEKTQPTKGVGGKAVAMVNPLVAEPQNVPQTPSVVELALTACLPYSLQYNTTQRDAGQGQITITIPLAQNPGTSSSGTQPQQQPPLGAFSVLSAGQCPLQPANTTTANSAIKTNPKASITASGPSSSCSGQVPIACPTSVPTHTPGPAPMPAPAVTHSTAPSDSLSYINSSSLPVTPLASGTQQAGGCNTCGCRGTCGGNGAHQTHSYFLPPQPARQMFGPPPPPFFHLPPSLCNSFAAQGHQNNGTPLPFYAHSGPPAAFLHAHSDHLLASQAGYSLPQMTPFHRFYPPVFPPVGLMSGGNNLKKTNNVSCYNCGMSGHYAQDCKQPSIDAGLTGGYRLKYVAPNSSEALDKND", "length": 858, "header": "tr|A0A8M9P861-1|A0A8M9P861_DANRE Isoform 1 of Zinc finger CCHC domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=zcchc2 PE=4 SV=2 CANONICAL=A0A8M9P861-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P861-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P861/entry#A0A8M9P861-1", "sequence": { "sequence": "MMKMKLRAAGGENYRCDLNSVNGADRESGIGAAQLDKEAVFEWFGLQLNPAGRVELLCGLLHMCQPLELRFLGACLEDLARRDFTVLRDFEIRANSPADLEGLVDVSDPVVLSKLLVYLSLLGSKSRECACILFRTLSRMDVGMYGALPEPETVDQLRLLFTMGSLHPAFSFYQREELRAQLDRLQRWSQFSRPGFLCPHREDDGDWTLCSNANPHLSSTSQREVVHIEKIILKEISVGGDGRHYSFEVKWSDSSSSAVTKSHRELEDFLLKLPKEQSPGGFEKGIVKLLSRGDQCESRDLERNLREKFLSLSQDVLRRCDISRFFLSDASVLPCSHCTSAPVARIHQPERGFSEDCSETSSLEEDVEAYNIRAAGLSNQRSECQRRGNCEQNGERVWKKENELEQNCTNDRRIFTAGQKNKGRSAGKRDRVRRVTAVKTSNGIQKPSAALMINQAACKDAGRDRYGDTSSESSNSVPSSPVHQKSLEDQDTESQSDNSAQEPTEKTQPTKGVGGKAVAMVNPLVAEPQNVPQTPSVVELALTACLPYSLQYNTTQRDAGQGQITITIPLAQNPGTSSSGTQPQQQPPLGAFSVLSAGQCPLQPANTTTANSAIKTNPKASITASGPSSSCSGQVPIACPTSVPTHTPGPAPMPAPAVTHSTAPSDSLSYINSSSLPVTPLASGTQQAGGCNTCGCRGTCGGNGAHQTHSYFLPPQPARQMFGPPPPPFFHLPPSLCNSFAAQGHQNNGTPLPFYAHSGPPAAFLHAHSDHLLASQAGYSLPQMTPFHRFYPPVFPPVGLMSGGNNLKKTNNVSCYNCGMSGHYAQDCKQPSIDAGLTGGYRLKYVAPNSSEALDKND", "length": 858, "header": "tr|A0A8M9P861-1|A0A8M9P861_DANRE Isoform 1 of Zinc finger CCHC domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=zcchc2 PE=4 SV=2 CANONICAL=A0A8M9P861-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PJ40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P861/entry#A0A8M9PJ40-1", "sequence": { "sequence": "MMKMKLRAAGGENYRCDLNSVNGADRESGIGAAQLDKEAVFEWFGLQLNPAGRVELLCGLLHMCQPLELRFLGACLEDLARRDFTVLRDFEIRANSPADLEGLVDVSDPVVLSKLLVYLSLLGSKSRECACILFRTLSRMDVGMYGALPEPETVDQLRLLFTMGSLHPAFSFYQREELRAQLDRLQRWSQFSRPGFLCPHREDDGDWTLCSNANPHLSSTSQREVVHIEKIILKEISVGGDGRHYSFEVKWSDSSSSAVTKSHRELEDFLLKLPKEQSPGGFEKGIVKLLSRGDQCESRDLERNLREKFLSLSQDVLRRCDISRFFLSDASVLPCSHCTSAPVARIHQPERGFSEDCSETSSLEEDVEAYNIRAAGLSNQRSECQRRGNCEQNGERVWKKENELEQNCTNDRRIFTAGQKNKGRSAGKRDRVRRVTAVKTSNGIQKPSAALMINQAACKDAGRDRYGDTSSESSNSVPSSPVHQKSLEDQDTESQSDNSAQEPTEKTQPTKGVGGKAVAMVNPLVAEPQNVPQTPSVVELALTACLPYSLQYNTTQRDAGQGQITITIPLAQNPGTSSSGTQPQQQPPLGAFSVLSAGQCPLQPANTTTANSAIKTNPKASITASGPSSSCSGQVPIACPTSVPTHTPGPAPMPAPAVTHSTAPSDSLSYINSSSLPVTPLASGTQQAGGCNTCGCRGTCGGNGAHQTHSYFLPPQPARQMFGPPPPPFFHLPPSLCNSFAAQGHQNNGTPLPFYAHSGPPAAFLHAHSDHLLASQAGYSLPQMTPFHRFYPPVFPPVGLMSGGNNLKKTNNVSCYNCGMSGHYAQDCKQPSIDAGLTGKWLPAEVCCPKLLRSTR", "length": 856, "header": "tr|A0A8M9PJ40-1|A0A8M9PJ40_DANRE Computationally mapped isoform of Zinc finger CCHC domain-containing protein 2 isoform X2 OS=Danio rerio OX=7955 GN=zcchc2 PE=4 SV=2 CANONICAL=A0A8M9P861-1" }, "locus": {} }, { "isoform_ac": "A0AC58HXR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P861/entry#A0AC58HXR2-1", "sequence": { "sequence": "MMKMKLRAAGGENYRCDLNSVNGADRESGIGAAQLDKEAVFEWFGLQLNPAGRVELLCGLLHMCQPLELRFLGACLEDLARRDFTVLRDFEIRANSPADLEGLVDVSDPVVLSKLLVYLSLLGSKSRECACILFRTLSRMDVGMYGALPEPETVDQLRLLFTMGSLHPAFSFYQREELRAQLDRLQRWSQFSRPGFLCPHREDDGDWTLCSNANPHLSSTSQREVVHIEKIILKEISVGGDGRHYSFEVKWSDSSSSAVTKSHRELEDFLLKLPKEQSPGGFEKGIVKLLSRGDQCESRDLERNLREKFLSLSQDVLRRCDISRFFLSDASVLPCSHCTSAPVARIHQPERGFSEDCSETSSLEEDVEAYNIRAAGLSNQRSECQRRGNCEQNGERVWKKENELEQNCTNDRRIFTAGQKNKGRSAGKRDRVRRVTAVKTSNGIQKPSAALMINQAACKDAGRDRYGDTSSESSNSVPSSPVHQKSLEDQDTESQSDNSAQEPTEKTQPTKGVGGKAVAMVNPLVAEPQNVPQTPSVVELALTACLPYSLQYNTTQRDAGQGQITITIPLAQNPGTSSSGTQPQQQPPLGAFSVLSAGQCPLQPANTTTANSAIKTNPKASITASGPSSSCSGQVPIACPTSVPTHTPGPAPMPAPAVTHSTAPSDSLSYINSSSLPVTPLASGTQQAGGCNTCGCRGTCGGNGAHQTHSYFLPPQPARQMFGPPPPPFFHLPPSLCNSFAAQGHQNNGTPLPFYAHSGPPAAFLHAHSDHLLASQAGYSLPQMTPFHRFYPPVFPPVGLMSGGNNLKKTNNVSCYNCGMSGHYAQDCKQPSIDAGLTGNTKETLLPCFREN", "length": 852, "header": "tr|A0AC58HXR2-1|A0AC58HXR2_DANRE Computationally mapped isoform of Zinc finger CCHC domain-containing protein 2 isoform X3 OS=Danio rerio OX=7955 GN=zcchc2 PE=4 SV=1 CANONICAL=A0A8M9P861-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:564789", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564789", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R4K3-1", "protein_name": "Zinc finger CCHC-type containing 14", "gene_name": "Zcchc14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVEKRCPLQRDGVYRWFSELPSPQRVEFLCGLLDLCIPLELRFLGSCLEDLARKDYHSLRDSEIKANNPADLGSLTNLTDEVVRSKLLVSLALLGSEQREAAGVLYRTLTHTDSIIHNYGLQLNEGRTGDEFLLLFTMASNHPAFSFHQKQVLRQELTQIQSSLNGGGGGGGGGGGGGKSAPGPSGALPTCSACHKMAPRTETPVSSISNSLENALHTSAHSTEEALPKRPLGKHGKVSVEKIDLKGLSHTKSDRGVECSFEVLWSDSSVTSVTKSSSEVTEFISKLSQLCPEENLDKLIPCLAGPDSFYVERNHVDLEAGLRFLASIPAHTLKHDHVRKFFSASSPSQQLQSPSPGNPSPPKVGAMMGVSGRPVCGVAGIPSSQSSTQHHLQHSASSSASLPHCSHTGGAGPALAYRTQVDNSPTILMPSGLQAPQPQEQNGILDWLRKLRLHKYYPVFKQLTMEKFLSLTEEDLNKFESLTMGAKKKLKTQLELEKEKSERRCLNSSAPSLVTSSGVARVTPTSHVGPVQPGRSSHASELRVEVEPPAHQLPREGSSSEYSSSSSSPMGVQAREESSDSAEESDRRVDIHVEGTEKEKPVMLLAHFPSSSARPTAQVLPVQNETGSSPAGHHPLPAQLMPAAPHLAPVRMLNSVHKSDRGSTDVKLLSSSVHSLLSLEERGKGPAPRSGTKVDKSFGGAVLDTLPSAAPHPPVQGLSGLVENTSVSPNVSFGPRAKVVHAATLDRVLKTAQQPALTVETSSAATGTPSTVLHVARPPIKLLLSSSVPADTAISGQTSCPNNGQISVPPAILNPRNALYTANTKVAFSAVSSVPVGPLQGSFCANSNTASPSSHPSTSFASMATLPSCPAPSSSPALSSVPESSFYSGGAGSSSPGNIPASSQSHHHHHHHQQPPAPPPPGCIVCTSCGCSGSCGSNGLTVSYANYFQHPFSGPSMFTFPFLPFSPMCGNGYVSTQQYGGGSAFPVVHTAYNGSVTPDPVLGGQSTFAVPPMQHFMTGTAGVHQAQGLVGSSNGSSHKKSGNLSCYNCGATGHRAQDCKQPSMDFNRQGTFRLKYAPPAESLDSTD", "length": 1087 }, "evidence": [ { "id": "FB:FBgn0032748", "url": "https://alliancegenome.org/gene/FB:FBgn0032748#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q498S6-1", "protein_name": "Zinc finger CCHC domain-containing protein 2", "gene_name": "Zcchc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRMKLPPKSTHPSEPPPDAEEPEADARPGAKAPPRRRRDCRPPPPPPTGLPRGPPPPPPSPPRGLEPPVASGPTAGAGMPGGGGHAAALREQERVYEWFGLVLGSAQRLEFLCGLLDLCNPLELRFLGSCLEDLARKDYHYLRDSEAKANGLSDPGSLADFREPAVRSRLIVYLALLGSENREAAGRLHRLLPQVDAVLRSLRATRVEGSRGSVEDEPGGDDEQDAEKDGPGPEGGGCAKLGTGGGLGFRAQEELLLLFTMASLHPAFSFHQRVTLREHLERLRSALRVEPEDAEVEPSNFAGSRAQNDSACGDYIQSNETGLVEQAQIPQDGLTVAPHRAQREAVHIEKIMLKGVQRRRADKYWEYTFKVNWSDLSVTTVTKTHQELQEFLLKLPKEFSSESFDKTILKALNQGSLRREERRHPDLEPILRQLFSTSPQAFLQSHKVRSFFRSISSESQHSFNNLQSSLKTSKILEHLKEDSSEASSQEEDVLQHTIIHKKHAGKSPAGNVATSCALLEGLTMQYAEQNGVVDWRNQGCAAIQHSEHCVSSADQLSAEKRSLSSVNKKKGKPQVEKEKIKKTENRLSSRINGIRLSAPQHAHGSTVKDMNLDVGSGHDTCGETSSESYSSPSSPRHDGRESLESEEEKDRDTDSNSEDSGNPSSARFAGHGSVTQTVSVQPPADTVSLGTENGNLLEAPLTSHKYPHIPFMPTLPCVMHNGAQKSEVVIPSPKSADGKAVGVLVPNPVAISTMMESTNAAPVGILGPAASGESEKHLELLASPLPIPSPFLPHSSAPALQLTLQSLKLQPPQGASENCPVNIPQQAATRLSIGSPNTALIPVHNPGAFPGSPVAATDPITKSASQVVGLNQMVPQIEGNTGTVPQPNNVKVVLPAAGLSAAQPPASYTFPGSPLAASVLPTQNSTVLNTATSAQPASTGISPAQSTVPPAVPTHTPGPAPSPSPALTHSTAQSDSTSYISAVGNTNANSTIVPPQPLGPCGSCGRRCSCGTNGNLQLNSYYYPNPMPGPMYRLPSFFTLPSICNGSYLNQAHQSNGNQLPFFLPQTPYANGLVHDPVMGSQASYGMQQMAGFGRLYPVYPAPNVVANTSGSGPKKNGSVSCYNCGVSGHYAQDCKQSSMEANQQGTYRLRYAPPLPPSNDTLDSAD", "length": 1168 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-269", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-269#orthology", "database": "AGR" }, { "id": "MGI:2444114", "url": "https://alliancegenome.org/gene/MGI:2444114#orthology", "database": "AGR" }, { "id": "RGD:1310626", "url": "https://alliancegenome.org/gene/RGD:1310626#orthology", "database": "AGR" }, { "id": "HGNC:22916", "url": "https://alliancegenome.org/gene/HGNC:22916#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q69ZB8-1", "protein_name": "Zinc finger CCHC domain-containing protein 2", "gene_name": "Zcchc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRMKLPPKSTHPSEPPPDAEEPEADARPGAKAPLRRRRDCRPPPPPTGLPRGPPPPPSPPRGLEPPVASGPTAGAGMPGGGGHAAALREQERVYEWFGLVLGSAQRLEFMCGLLDLCNPLELRFLGSCLEDLARKDYHYLRDSEAKANGLSDPGSLADFREPAVRSRLIVYLALLGSENREAAGRLHRLLPQVDAVLRSLRATRAEGSRGSVEDEPSGDGEQDAEKDGPGPEGSGCAKLGTGGGLGFRAQEELLLLFTMASLHPAFSFHQRVTLREHLERLRSALRVEPEDAEVEPSNFAGSRAQNDSACGDYIQSNETGLVEQAQIPPDGLTVAPHRAQREAVHIEKIMLKGVQRKRADKYWEYTFKVNWSDLSVTTVTKTHQELQEFLLKLPKEFSSESFDKTILKALNQGSLRREERRHPDLEPILRQLFSTSPQAFLQSHKVRSFFRSISSESQHNFNNLQSSLKTSKILEHLKEDSSEASSQEEDVLQHTIIHKKHAGKSPALNVATSCSPLDGLTMQYAEQNGIVDWRNQGCAAIQHSEHCVSSADQHSAEKRSLSSGNKKKGKPQVEKEKVKKTEDRLNSRINGIRLSAPQHVHGSTVKDMNLDIGSGHDTCGETSSESYSSPSSPRHDGRESLESEEEKDRDSDSNSEDSVNPSSARFSGYGSVAQTIAVKPPAETVSLGTEDGNLLEAALTSHKYPHIPFMPTLHCVTHNGAQKSQVVIPSPKSADGKTLGMLVPNAVAISAVMESSNSAPVGILGPAASGESEKHLELLASPLPLPSTFLPHSSAPALQLTLQSLKLQPPQGSSDSCPVSIPPQPTGSLSIGSPNTAFIPVHNPGSFPGSPVATTDPITKSAPQVVGLNQMVPQIEGNTGTVPQPSNVKVVLPAAGLSAAQPPASFPFPGSPQAASALPTQNSSALNAATSAQPASTGISPSQSTVPPAVPTHTPGPAPSPSPALTHSTAQSDSTSYISAVGNTNANGTIVPPQQMGPCGSCGRRCSCGTNGNLQLNSYYYPNPMPGPMYRLPSFFTLPSICNGSYLNQAHQSNGNQLPFFLPQTPYANGLVHDPVMGSQASYGMQQMAGFGRLYPVYPAPNVVANTSGSGPKKNGNVSCYNCGVSGHYAQDCKQSSMEANQQGTYRLRYAPPLPPSNDTLDSAD", "length": 1166 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-269", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-269#orthology", "database": "AGR" }, { "id": "MGI:2444114", "url": "https://alliancegenome.org/gene/MGI:2444114#orthology", "database": "AGR" }, { "id": "RGD:1310626", "url": "https://alliancegenome.org/gene/RGD:1310626#orthology", "database": "AGR" }, { "id": "FB:FBgn0032748", "url": "https://alliancegenome.org/gene/FB:FBgn0032748#orthology", "database": "AGR" }, { "id": "HGNC:22916", "url": "https://alliancegenome.org/gene/HGNC:22916#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VIG0-1", "protein_name": "Zinc finger CCHC domain-containing protein 14", "gene_name": "Zcchc14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"FB:FBgn0032748", "url": "https://alliancegenome.org/gene/FB:FBgn0032748#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WYQ9-1", "protein_name": "Zinc finger CCHC domain-containing protein 14", "gene_name": "ZCCHC14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNHPAFSFHQKQVLRQELTQIQSSLNGGGGHGGKGAPGPGGALPTCPACHKITPRTEAPVSSVSNSLENALHTSAHSTEESLPKRPLGKHSKVSVEKIDLKGLSHTKNDRNVECSFEVLWSDSSITSVTKSSSEVTEFISKLCQLYPEENLEKLIPCLAGPDAFYVERNHVDLDSGLRYLASLPSHVLKNDHVRRFLSTSSPPQQLQSPSPGNPSLSKVGTVMGVSGRPVCGVAGIPSSQSGAQHHGQHPAGSAAPLPHCSHAGSAGSALAYRTQMDTSPAILMPSSLQTPQTQEQNGILDWLRKLRLHKYYPVFKQLSMEKFLSLTEEDLNKFESLTMGAKKKLKTQLELEKEKSERRCLNPSAPPLVTSSGVARVPPTSHVGPVQSGRGSHAAELRVEVEQPHHQLPREGSSSEYSSSSSSPMGVQAREESSDSAEENDRRVEIHLESSDKEKPVMLLNHFTSSSARPTAQVLPVQNEASSNPSGHHPLPPQMLSAASHITPIRMLNSVHKPERGSADMKLLSSSVHSLLSLEERNKGSGPRSSMKVDKSFGSAMMDVLPASAPHQPVQVLSGLSESSSMSPTVSFGPRTKVVHASTLDRVLKTAQQPALVVETSTAATGTPSTVLHAARPPIKLLLSSSVPADSAISGQTSCPNNVQISVPPAIINPRTALYTANTKVAFSAMSSMPVGPLQGGFCANSNTASPSSHPSTSFANMATLPSCPAPSSSPALSSVPESSFYSSSGGGGSTGNIPASNPNHHHHHHHQQPPAPPQPAPPPPGCIVCTSCGCSGSCGSSGLTVSYANYFQHPFSGPSVFTFPFLPFSPMCSSGYVSAQQYGGGSTFPVVHAPYSSSGTPDPVLSGQSTFAVPPMQNFMAGTAGVYQTQGLVGSSNGSSHKKSGNLSCYNCGATGHRAQDCKQPSMDFNRPGTFRLKYAPPAESLDSTD", "length": 949 }, "evidence": [ { "id": "FB:FBgn0032748", "url": "https://alliancegenome.org/gene/FB:FBgn0032748#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9C0B9-1", "protein_name": "Zinc finger CCHC domain-containing protein 2", "gene_name": "ZCCHC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRMKLPLKPTHPAEPPPEAEEPEADARPGAKAPSRRRRDCRPPPPPPPPAGPSRGPLPPPPPPRGLGPPVAGGAAAGAGMPGGGGGPSAALREQERVYEWFGLVLGSAQRLEFMCGLLDLCNPLELRFLGSCLEDLARKDYHYLRDSEAKANGLSDPGPLADFREPAVRSRLIVYLALLGSENREAAGRLHRLLPQVDSVLKSLRAARGEGSRGGAEDERGEDGDGEQDAEKDGSGPEGGIVEPRVGGGLGSRAQEELLLLFTMASLHPAFSFHQRVTLREHLERLRAALRGGPEDAEVEVEPCKFAGPRAQNNSAHGDYMQNNESSLIEQAPIPQDGLTVAPHRAQREAVHIEKIMLKGVQRKRADKYWEYTFKVNWSDLSVTTVTKTHQELQEFLLKLPKELSSETFDKTILRALNQGSLKREERRHPDLEPILRQLFSSSSQAFLQSQKVHSFFQSISSDSLHSINNLQSSLKTSKILEHLKEDSSEASSQEEDVLQHAIIHKKHTGKSPIVNNIGTSCSPLDGLTMQYSEQNGIVDWRKQSCTTIQHPEHCVTSADQHSAEKRSLSSINKKKGKPQTEKEKIKKTDNRLNSRINGIRLSTPQHAHGGTVKDVNLDIGSGHDTCGETSSESYSSPSSPRHDGRESFESEEEKDRDTDSNSEDSGNPSTTRFTGYGSVNQTVTVKPPVQIASLGNENGNLLEDPLNSPKYQHISFMPTLHCVMHNGAQKSEVVVPAPKPADGKTIGMLVPSPVAISAIRESANSTPVGILGPTACTGESEKHLELLASPLPIPSTFLPHSSTPALHLTVQRLKLPPPQGSSESCTVNIPQQPPGSLSIASPNTAFIPIHNPGSFPGSPVATTDPITKSASQVVGLNQMVPQIEGNTGTVPQPTNVKVVLPAAGLSAAQPPASYPLPGSPLAAGVLPSQNSSVLSTAATSPQPASAGISQAQATVPPAVPTHTPGPAPSPSPALTHSTAQSDSTSYISAVGNTNANGTVVPPQQMGSGPCGSCGRRCSCGTNGNLQLNSYYYPNPMPGPMYRVPSFFTLPSICNGSYLNQAHQSNGNQLPFFLPQTPYANGLVHDPVMGSQANYGMQQMAGFGRFYPVYPAPNVVANTSGSGPKKNGNVSCYNCGVSGHYAQDCKQSSMEANQQGTYRLRYAPPLPPSNDTLDSAD", "length": 1178 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-269", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-269#orthology", "database": "AGR" }, { "id": "MGI:2444114", "url": "https://alliancegenome.org/gene/MGI:2444114#orthology", "database": "AGR" }, { "id": "RGD:1310626", "url": "https://alliancegenome.org/gene/RGD:1310626#orthology", "database": "AGR" }, { "id": "HGNC:22916", "url": "https://alliancegenome.org/gene/HGNC:22916#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VJ08-1", "protein_name": "CCHC-type domain-containing protein", "gene_name": "TU37B1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MICKQDVLQWFEKLESYNRIETMYALLTACLPFELRFLGTLLEEQGRCDSETLRGMELRANNPHELAADMVNCQKGDPTDRKIRRKMALYLALIRACNRNCVSEIYRTLECWGECDFSCINDQDTLLELLLVYTMAAIHPVFSMEEQKKIFGILAKIKENKLVAERFAPQMQRQTQTPVLQHPHPPSPHDLVIQQQPPHVIHQIPGPQQAPPHPQHPQMVQVLQTPQGNIPMIFPQHFQKLLPSSDGTHQISVDGMPHLMQPNITIPADTSAIISHQNTGWTMRHYVPQPPHQQPALQQQQPQSLDHQVPPASSPMLSQQSSPSSSRTTSPQRDRSLINVPLQAQQQPHQQQQMRGMSQRMADQKNTRRPSAETTPPPTSIGGEQQHDSVNEGGSSNSSGTSLHRLIRNGFPRLGHNHRVKANTFIPQHQQQQQQHHFQNPNYNMNVMMQSMNINDDGSGSMMNSMNSTKSAATTGSESGSSNGSCGDLSPSETPTPTQLSLPLHNSVDAGMGMITTVLPTGLGNYQPKPHHFSYKQQQQQMNLQQRLNGRNGMDKTYQQVYTTGTPSIVSDAQTISSASLQQQQPQTLLISQSPVSTPTTTVLLQPQQPPPTTYNTSYPYHQRGPPPPQQTIFQAHSAPPPQTVRGGFRYPMGPPHNGELIYPTFHTSLAFLPMTAGGTPTAVTPAQLQSTAAVVSTNAVSVQTVPTPQQQQVPSTTPYSALTVCPITGAGGGGTAPKVISCYNCGSQTHSGRECQEASMEDVTRSASYKLDYSETSMDSSATGDHHKDVGSVQINSTATAGTVTSTVK", "length": 810 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070912-269", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-269#orthology", "database": "AGR" }, { "id": "MGI:2444114", "url": "https://alliancegenome.org/gene/MGI:2444114#orthology", "database": "AGR" }, { "id": "FB:FBgn0032748", "url": "https://alliancegenome.org/gene/FB:FBgn0032748#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P861", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P861" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P861", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P861" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 407, "end_pos": 409, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 606, "end_pos": 608, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" }, { "start_pos": 748, "end_pos": 750, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P861", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P861" }, { "id": "PS50158", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC-type", "eco_id": "ECO_0000259", "start_pos": 815, "end_pos": 830, "start_aa": "Cys", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 407, "end_pos": 409 }, { "start_pos": 553, "end_pos": 555 }, { "start_pos": 606, "end_pos": 608 }, { "start_pos": 672, "end_pos": 674 }, { "start_pos": 748, "end_pos": 750 }, { "start_pos": 812, "end_pos": 814 }, { "start_pos": 849, "end_pos": 851 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P869-1", "uniprot_ac": "A0A8M9P869", "uniprot_id": "A0A8M9P869_DANRE", "mass": { "chemical_mass": 67872.0, "monoisotopic_mass": 67872.0 }, "refseq": { "ac": "XP_068070187", "name": "growth factor receptor-bound protein 10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070187" }, "gene_names": [ { "name": "grb10b", "type": "recommended", "evidence": [ { "id": "A0A8M9P869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" } ] }, { "name": "grb10b", "type": "synonym", "evidence": [ { "id": "XP_068070187", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070187" } ] } ], "protein_names": [ { "name": "Growth factor receptor-bound protein 10 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869/entry#names_and_taxonomy" } ] }, { "name": "growth factor receptor-bound protein 10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_068070187", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070187" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068070187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070187" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P869", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "grb10b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091020-12", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091020-12", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000035308", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000035308", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01259", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01259", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10415", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10415", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "562032", "url": "https://www.ncbi.nlm.nih.gov/gene/562032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035037", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035037", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039664", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039664", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039665", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039665", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562032", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562032", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QNGQHTR", "url": "https://omabrowser.org/oma/group/QNGQHTR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P869", "url": "https://www.orthodb.org/?gene=A0A8M9P869", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1QSC3", "url": "https://www.orthodb.org/?gene=F1QSC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11243:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11243:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08947", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08947", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_068070187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070187", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P869", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P869-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HIW9", "url": "https://www.uniprot.org/uniprotkb/A0AC58HIW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HIW9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HIW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QSC3", "url": "https://www.uniprot.org/uniprotkb/F1QSC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QSC3-1", "url": "https://www.uniprot.org/uniprotkb/F1QSC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091020-12", "url": "https://zfin.org/ZDB-GENE-091020-12", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAVAGCPDYFLHHPNYKQDNVDRAANHRQADLIGPSFQQSASHNSPSHQEDDVDLEALVNDMNSSLESLYTSCSVQSESTPLLHNGQPHRPSAYHTHAQPISPHQRLRRSQPMNILAVRRLQEEAQQYRTSSLPAIPNPFPELCSPASSPTLSSGSLPQCQPSDKYIIKIFSEDGMGKVVEIPADMTARDLCQFLVYKNHCVDDNSWALVEHHPALGLERCLEDHELVVQVQTSMISESKFLFRKNYAKYEFFKNPLNFFPEQMIAWCQETNGTIPPSQLLQNFLNSSSCPEIQGYLYVKEMGRKSWKKLYVFLRRSGLYFSTKGTSKEPRHLQLLADLEDSNVFTVITGRKLHSAPTDFEFCIKPNKVRNEVKELRMLCAEDEQSRTCWMTAFRLFKYGILLYQNYKIHQQRKTLLSHFSAPVRSVSESSLVAMDFSGRIGRVIDNPVEAQSAAMEEGHAWRKKSQQRMNILGSPSSLHPSSLSGVIHRTQLWFHGRISREESHKLIHQQGRVDGMFLLRDSQSNPKAFVLTLCHHQKIKHFQILLCEEDGQMFLSLDDGAVKFTDLIQLVEFYTLNRGVLPCKLKHPCTTVAL", "length": 595, "header": "tr|A0A8M9P869-1|A0A8M9P869_DANRE Isoform 1 of Growth factor receptor-bound protein 10 isoform X1 OS=Danio rerio OX=7955 GN=grb10b PE=3 SV=1 CANONICAL=A0A8M9P869-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P869-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869/entry#A0A8M9P869-1", "sequence": { "sequence": "MAVAGCPDYFLHHPNYKQDNVDRAANHRQADLIGPSFQQSASHNSPSHQEDDVDLEALVNDMNSSLESLYTSCSVQSESTPLLHNGQPHRPSAYHTHAQPISPHQRLRRSQPMNILAVRRLQEEAQQYRTSSLPAIPNPFPELCSPASSPTLSSGSLPQCQPSDKYIIKIFSEDGMGKVVEIPADMTARDLCQFLVYKNHCVDDNSWALVEHHPALGLERCLEDHELVVQVQTSMISESKFLFRKNYAKYEFFKNPLNFFPEQMIAWCQETNGTIPPSQLLQNFLNSSSCPEIQGYLYVKEMGRKSWKKLYVFLRRSGLYFSTKGTSKEPRHLQLLADLEDSNVFTVITGRKLHSAPTDFEFCIKPNKVRNEVKELRMLCAEDEQSRTCWMTAFRLFKYGILLYQNYKIHQQRKTLLSHFSAPVRSVSESSLVAMDFSGRIGRVIDNPVEAQSAAMEEGHAWRKKSQQRMNILGSPSSLHPSSLSGVIHRTQLWFHGRISREESHKLIHQQGRVDGMFLLRDSQSNPKAFVLTLCHHQKIKHFQILLCEEDGQMFLSLDDGAVKFTDLIQLVEFYTLNRGVLPCKLKHPCTTVAL", "length": 595, "header": "tr|A0A8M9P869-1|A0A8M9P869_DANRE Isoform 1 of Growth factor receptor-bound protein 10 isoform X1 OS=Danio rerio OX=7955 GN=grb10b PE=3 SV=1 CANONICAL=A0A8M9P869-1" }, "locus": {} }, { "isoform_ac": "A0AC58HIW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869/entry#A0AC58HIW9-1", "sequence": { "sequence": "MPSCSPDCCLLRPGEIIKIFSEDGMGKVVEIPADMTARDLCQFLVYKNHCVDDNSWALVEHHPALGLERCLEDHELVVQVQTSMISESKFLFRKNYAKYEFFKNPLNFFPEQMIAWCQETNGTIPPSQLLQNFLNSSSCPEIQGYLYVKEMGRKSWKKLYVFLRRSGLYFSTKGTSKEPRHLQLLADLEDSNVFTVITGRKLHSAPTDFEFCIKPNKVRNEVKELRMLCAEDEQSRTCWMTAFRLFKYGILLYQNYKIHQQRKTLLSHFSAPVRSVSESSLVAMDFSGRIGRVIDNPVEAQSAAMEEGHAWRKKSQQRMNILGSPSSLHPSSLSGVIHRTQLWFHGRISREESHKLIHQQGRVDGMFLLRDSQSNPKAFVLTLCHHQKIKHFQILLCEEDGQMFLSLDDGAVKFTDLIQLVEFYTLNRGVLPCKLKHPCTTVAL", "length": 444, "header": "tr|A0AC58HIW9-1|A0AC58HIW9_DANRE Computationally mapped isoform of Growth factor receptor-bound protein 10 isoform X3 OS=Danio rerio OX=7955 GN=grb10b PE=3 SV=1 CANONICAL=A0A8M9P869-1" }, "locus": {} }, { "isoform_ac": "F1QSC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869/entry#F1QSC3-1", "sequence": { "sequence": "MAVAGCPDYFLHHPNYKDNVDRAANHRQADLIGPSFQQSASHNSPSHQEDDVDLEALVNDMNSSLESLYTSCSVQSESTPLLHNGQPHRPSAYHTHAQPISPHQRLRRSQPMNILAVRRLQEEAQQYRTSSLPAIPNPFPELCSPASSPTLSSGSLPQCQPSDKYIIKIFSEDGMGKVVEIPADMTARDLCQFLVYKNHCVDDNSWALVEHHPALGLERCLEDHELVVQVQTSMISESKFLFRKNYAKYEFFKNPLNFFPEQMIAWCQETNGTIPPSQLLQNFLNSSSCPEIQGYLYVKEMGRKSWKKLYVFLRRSGLYFSTKGTSKEPRHLQLLADLEDSNVFTVITGRKLHSAPTDFEFCIKPNKVRNEVKELRMLCAEDEQSRTCWMTAFRLFKYGILLYQNYKIHQQRKTLLSHFSAPVRSVSESSLVAMDFSGRIGRVIDNPVEAQSAAMEEGHAWRKKSQQRMNILGSPSSLHPSSLSGVIHRTQLWFHGRISREESHKLIHQQGRVDGMFLLRDSQSNPKAFVLTLCHHQKIKHFQILLCEEDGQMFLSLDDGAVKFTDLIQLVEFYTLNRGVLPCKLKHPCTTVAL", "length": 594, "header": "tr|F1QSC3-1|F1QSC3_DANRE Computationally mapped isoform of Growth factor receptor-bound protein 10 isoform X2 OS=Danio rerio OX=7955 GN=grb10b PE=3 SV=2 CANONICAL=A0A8M9P869-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:562032", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562032", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P405-1", "protein_name": "Growth factor receptor bound protein 10", "gene_name": "GRB10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALAGCPDSFLHLPYRIDNVDQTSAHGRRDLVEPGFQEPSNRMSLNHQDDDVDLEALVNDMNSSFESLYSTCSMQSETTPLLQNGQLNRSPLPTSGSSALQPTSPRQKVQRSQPVRIMAVRRLQEEEQQFRTSSLPAIPNPFPELCSPASSPVLAPGSLPQSQPANKHDVKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELIVQVESTMGSESKFLFRKNYAKYEFFKNPMNFFPEQMVAWCQQTNGSIPQSQLLQNFLNSSSCPEIQGFLHVKELGRKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGKKLYNAPAEYGFCIKPNRVRNETKELRLLCAEDEQSRTCWMTAFRLLKYGMLLYQNYRIPQQRKAMLPHFSTPVRSVSENSLVAMDFSGQIGRVIENPVEAQSAAMEEGHAWRKRSTRMNILGSQSPLHPSTLSTVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKHFQILPCEDDGQIFFSLDDGNTKFSDLIQLVEFYQLNKGVLPCKLKHHCIRVAL", "length": 596 }, "evidence": [ { "id": "A0A8M9P869", "url": "https://omabrowser.org/oma/group/A0A8M9P869/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9S0B2-1", "protein_name": "Growth factor receptor bound protein 10", "gene_name": "GRB10", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWFEDRGEEPMALAGGPDSFLHHPYHQDKVEQTPPQRPGELAGPGFPAPPDRLASHQEDDVDLEALVNDMDASLESLCAASETVPLLHNGQHSRGPVPRARVLQPQAAPRQRVQRSQPVSILAVRRLQEEDLHLRTSSLPAIPNPFPELCGPGSPPALTPGSLPPGPAAAKQDVKVFSEDGTSKVVEILADMTARDLCQLLVYRSHCVDDNSWALVEHHPHLGLERCLEDHELVVQVESTMASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSHTQLLQNFLNSSSCPEIQGFLHVKELGRKSWKKLYVCLRRSGLYCSTKGASKGGPLPHFPALMCGLCVLLIAAEAQEPRHLQLLADLEDSSIFSLIAGRKQYSAPTDYGFCIKPNRVRNEAKELRLLCAEDEQSRTCWMTACRLLKYGMLLYQNYRIPQQRKAMLSHFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRSTRMNILGSQSPLHPSALSTVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCRLKHHCIRVAL", "length": 622 }, "evidence": [ { "id": "A0A8M9P869", "url": "https://omabrowser.org/oma/group/A0A8M9P869/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B5KFD7-1", "protein_name": "Growth factor receptor-bound protein 10", "gene_name": "Grb10", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALAGGPDSFLHHPYYQDQVEQTSPHHPRDLAGPGFPAQPDRLAPHQEDDVDLEALVNDMDASLESLCSASETAPLLHNGQHARGPPPPGARPLRPQASPRHRVPRSQPLHILAARRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLSPGSLPPGQAAAKQDVKVFSEDGTCKVVEILADMTARDLCQLLVYRSHCVDDNSWTLVEHHPHLGLERGLEDHERVTQVQHTLASESKFLFRKNYAKYEFFKNPTNFFPEQMVTWCQQSNGSQTQLLQNFLNSSSCPEIQGFLHVKELGRKSWKKLYVCLRRSGLYCSTKGASKEPRHLQLLADLEDSSIFSLIAGRKQYGAPTDYGFCIKPNRVRTEAKELRLLCAEDEQSRTCWMTAFRLLKYGMLLYQNYRVPQQRKAVLSPFSAPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRSTRMNILGSQSPLHPSTLSTVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL", "length": 589 }, "evidence": [ { "id": "A0A8M9P869", "url": "https://omabrowser.org/oma/group/A0A8M9P869/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P0CE43-1", "protein_name": "Growth factor receptor-bound protein 10", "gene_name": "Grb10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNDINSSVESLNSACNMQSDTDTVPLLENGQSASNQPSASSSRGQPQASPRQKMQRSQPVHIQPLRRLQEEDQQLRTSSLPAIPNPFPELAGGAPGSPPSVAPSSLPPPPSQPPAKHFPPGFQLAKLTRPGLWTKTTARFSKRQPKNQCQTDTANAVSRIPTSQMEKLRLRKDVKVFSEDGTSKVVEILTDMTARDLCQLLVYKSHCVDDNSWTLVEHHPQLGLERCLEDHEIVVQVESTMPSESKFLFRKNYAKYEFFKNPVNFFPDQMVTWCQQSNGGQAQLLQNFLNSSSCPEIQGFLQVKEVGRKSWKKLYVCLRRSGLYYSTKGTSKEPRHLQLLADLEESSIFYLIAGKKQYNAPNEHGMCIKPNKAKIEMKELRLLCAEDEQIRTCWMTAFRLLKYGMLLYQNYRIPQQRKGLAPPFNAPMRSVSENSLVAMDFSGQIGRVIDNPAEAQSAALEEGHAWRKRSTRMNILSSQSPLHPSTLNSVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHQQKIRNFQILPCEDDGQTFFTLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL", "length": 599 }, "evidence": [ { "id": "HGNC:4564", "url": "https://alliancegenome.org/gene/HGNC:4564#orthology", "database": "AGR" }, { "id": "RGD:1566234", "url": "https://alliancegenome.org/gene/RGD:1566234#orthology", "database": "AGR" }, { "id": "MGI:103232", "url": "https://alliancegenome.org/gene/MGI:103232#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091020-12", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091020-12#orthology", "database": "AGR" }, { "id": "A0A8M9P869", "url": "https://omabrowser.org/oma/group/A0A8M9P869/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13322-1", "protein_name": "Growth factor receptor-bound protein 10", "gene_name": "GRB10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALAGCPDSFLHHPYYQDKVEQTPRSQQDPAGPGLPAQSDRLANHQEDDVDLEALVNDMNASLESLYSACSMQSDTVPLLQNGQHARSQPRASGPPRSIQPQVSPRQRVQRSQPVHILAVRRLQEEDQQFRTSSLPAIPNPFPELCGPGSPPVLTPGSLPPSQAAAKQDVKVFSEDGTSKVVEILADMTARDLCQLLVYKSHCVDDNSWTLVEHHPHLGLERCLEDHELVVQVESTMASESKFLFRKNYAKYEFFKNPMNFFPEQMVTWCQQSNGSQTQLLQNFLNSSSCPEIQGFLHVKELGKKSWKKLYVCLRRSGLYCSTKGTSKEPRHLQLLADLEDSNIFSLIAGRKQYNAPTDHGLCIKPNKVRNETKELRLLCAEDEQTRTCWMTAFRLLKYGMLLYQNYRIPQQRKALLSPFSTPVRSVSENSLVAMDFSGQTGRVIENPAEAQSAALEEGHAWRKRSTRMNILGSQSPLHPSTLSTVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL", "length": 594 }, "evidence": [ { "id": "HGNC:4564", "url": "https://alliancegenome.org/gene/HGNC:4564#orthology", "database": "AGR" }, { "id": "RGD:1566234", "url": "https://alliancegenome.org/gene/RGD:1566234#orthology", "database": "AGR" }, { "id": "MGI:103232", "url": "https://alliancegenome.org/gene/MGI:103232#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091020-12", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091020-12#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60760-1", "protein_name": "Growth factor receptor-bound protein 10", "gene_name": "Grb10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNNDINSSVESLNSACNMQSDTDTAPLLEDGQHASNQGAASSSRGQPQASPRQKMQRSQPVHILRRLQEEDQQLRTASLPAIPNPFPELTGAAPGSPPSVAPSSLPPPPSQPPAKHCGRCEKWIPGENTRGNGKRKIWRWQFPPGFQLSKLTRPGLWTKTTARFSKKQPKNQCPTDTVNPVARMPTSQMEKLRLRKDVKVFSEDGTSKVVEILTDMTARDLCQLLVYKSHCVDDNSWTLVEHHPQLGLERCLEDHEIVVQVESTMPSESKFLFRKNYAKYEFFKNPVNFFPDQMVNWCQQSNGGQAQLLQNFLNTSSCPEIQGFLQVKEVGRKSWKKLYVCLRRSGLYYSTKGTSKEPRHLQLLADLEESSIFYLIAGKKQYNAPNEHGMCIKPNKAKTEMKELRLLCAEDEQIRTCWMTAFRLLKYGMLLYQNYRIPQRKGLPPPFNAPMRSVSENSLVAMDFSGQIGRVIDNPAEAQSAALEEGHAWRKRSTRMNILSSQSPLHPSTLNAVIHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCEDDGQTFFTLDDGNTKFSDLIQLVDFYQLNKGVLPCKLKHHCIRVAL", "length": 621 }, "evidence": [ { "id": "HGNC:4564", "url": "https://alliancegenome.org/gene/HGNC:4564#orthology", "database": "AGR" }, { "id": "RGD:1566234", "url": "https://alliancegenome.org/gene/RGD:1566234#orthology", "database": "AGR" }, { "id": "MGI:103232", "url": "https://alliancegenome.org/gene/MGI:103232#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091020-12", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091020-12#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of insulin receptor signaling pathway", "id": "GO:0046627", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046627", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P869", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" } ], "pmid": "" }, { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P869", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" } ], "pmid": "" }, { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P869", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" } ], "pmid": "" }, { "name": "negative regulation of Wnt signaling pathway", "id": "GO:0030178", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030178", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P869", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" } ], "pmid": "" }, { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P869", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "insulin receptor binding", "id": "GO:0005158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005158", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P869", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" } ], "pmid": "" }, { "name": "signaling receptor complex adaptor activity", "id": "GO:0030159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030159", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P869", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P869", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 290, "end_pos": 399, "start_aa": "Cys", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 164, "end_pos": 248, "start_aa": "Asp", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P869", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P869" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 494, "end_pos": 590, "start_aa": "Trp", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 272, "end_pos": 274 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P879-1", "uniprot_ac": "A0A8M9P879", "uniprot_id": "A0A8M9P879_DANRE", "mass": { "chemical_mass": 153285.0, "monoisotopic_mass": 153285.0 }, "refseq": { "ac": "XP_021322537", "name": "zinc finger protein 628 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322537" }, "gene_names": [ { "name": "znf628", "type": "recommended", "evidence": [ { "id": "A0A8M9P879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879" } ] }, { "name": "znf628", "type": "synonym", "evidence": [ { "id": "XP_021322537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322537" } ] } ], "protein_names": [ { "name": "Zinc finger protein 628 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 628 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322537" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322537.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322537" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P879", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "znf628", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041111-291", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041111-291", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "492716", "url": "https://www.ncbi.nlm.nih.gov/gene/492716", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:492716", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492716", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P879", "url": "https://www.orthodb.org/?gene=A0A8M9P879", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24381:SF443", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24381:SF443", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322537", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P879", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P879-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDH8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041111-291", "url": "https://zfin.org/ZDB-GENE-041111-291", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MANTVATLVVQTELLTSQTPSALSPFPSLLPSVEDGEEDGGKGEEEGKETETVVLTGDLVTSSTPPVTTVAQNPEHPFQCLDCGKSFKWSSRLAHHQRSHNNERPYRCNICPKAFKGSSALLYHQRSHSGEKPYKCDDCGKAFKRSSLLQIHRSVHTGLRTFQCSYCPLTFKWSSHYQYHLRQHTGECPYPCDSCSKAFKNSSSLRRHKNVHLGFKPYVCDVCNKAFSQSTNLRQHMRIHTGERPYICGDCGRSFTHSSNLALHRISHMDGKGKSAGKAGGVGSATREVEVVLTEDLNTVGMSISEMVGLVGGQEGAVGQVFLSHSTPSPATSGPANQNLLPQLTLTSTSSSVTDTDHIHMSKGDTCANVLLFSCGSCNETFSTQIHLEEHQTLHLDSLGPAGGGVVATESCTEADGAGVSLVGATPLLADFEEVVETTTVADSGQGAELLGLDAVRNESGQAQYDLLQTFTASVNQLTSDNSLPAAQATTDCTYCGKTFKTSSGLTRHVAQAHPRTPSDSRTQFNCSACDRSFPLLSSLLNHQHSHTPEQRLLAEAEAEAEIVCPSLSLPLPSLKREGEDGEREIHVSLIAVTEEGERRAVKPSAKASGKGSRRGGGSKTSAANNERPYRCSECGKSFKGSSGLRYHMRDHTGERPYRCTECGKSFKRSSLLSIHQRVHTGVRAFQCPYCPLTFKWSSHYQYHLRQHTGERPYVCQECGKSFKNTSCLRRHSQLHSGLRPHACSVCGKAFSQTSNLKQHERTHSGERPFQCSQCHKSFTHSSNLQLHLRTHSSHKDFKCQHCGKEFVMLSYLQRHLRTHLRTSAGDVACTKEAGKVVKGSGASETATLNVNLNVPGGLTSLFPTDSNSTLILSPPNLDIPPNTSQNYFMIQTTSGLQLIPLSNPTPTQPAPPPPPPPPPQNFLLLQCQSNNGNQPSLILVPTASSTNTLPTPSEPQTLPLVQTIPAMPQVLAAPQIQIQPFQPVQTQQRFILTNNNAPLITPQPQNTSTIARPILGSLARSRKGATRRGRKPKAATQKSPSALHTTPVKQPLRLSSAGSTSPTISSVTSAASVKTMFPKLNANNPPAVLPVSTCQVPESPSVPSVSIMSVTPNSTLTNSSPMLSSDPESVAVKKAVKEISREHFVLCLKKEMENGEQGDGMEVKVEMGGENDAERSYVLQIEGEHQEEGENGEGGEKSYVLRFQTEGECEGEAGKDKTGMVSLNLLQEWTEQSEGHGAANAEGNVDVEKSFVLHFQTEPQNEDDIQPSSGFIGGPGEDLSLSCHPGQALVPLEGQDVVFELGDETKIDGSTGAGDSVQMIALIEGEGNSSGARGSFKGAVGANSGQMEGIFQLEGGEGIVIIEVSTSSLRESGIEAADVGHALVEGTEENQTNDAQGGHEVMSEELKVAETESLSTSEIGLIGT", "length": 1425, "header": "tr|A0A8M9P879-1|A0A8M9P879_DANRE Isoform 1 of Zinc finger protein 628 isoform X1 OS=Danio rerio OX=7955 GN=znf628 PE=3 SV=2 CANONICAL=A0A8M9P879-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P879-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879/entry#A0A8M9P879-1", "sequence": { "sequence": "MANTVATLVVQTELLTSQTPSALSPFPSLLPSVEDGEEDGGKGEEEGKETETVVLTGDLVTSSTPPVTTVAQNPEHPFQCLDCGKSFKWSSRLAHHQRSHNNERPYRCNICPKAFKGSSALLYHQRSHSGEKPYKCDDCGKAFKRSSLLQIHRSVHTGLRTFQCSYCPLTFKWSSHYQYHLRQHTGECPYPCDSCSKAFKNSSSLRRHKNVHLGFKPYVCDVCNKAFSQSTNLRQHMRIHTGERPYICGDCGRSFTHSSNLALHRISHMDGKGKSAGKAGGVGSATREVEVVLTEDLNTVGMSISEMVGLVGGQEGAVGQVFLSHSTPSPATSGPANQNLLPQLTLTSTSSSVTDTDHIHMSKGDTCANVLLFSCGSCNETFSTQIHLEEHQTLHLDSLGPAGGGVVATESCTEADGAGVSLVGATPLLADFEEVVETTTVADSGQGAELLGLDAVRNESGQAQYDLLQTFTASVNQLTSDNSLPAAQATTDCTYCGKTFKTSSGLTRHVAQAHPRTPSDSRTQFNCSACDRSFPLLSSLLNHQHSHTPEQRLLAEAEAEAEIVCPSLSLPLPSLKREGEDGEREIHVSLIAVTEEGERRAVKPSAKASGKGSRRGGGSKTSAANNERPYRCSECGKSFKGSSGLRYHMRDHTGERPYRCTECGKSFKRSSLLSIHQRVHTGVRAFQCPYCPLTFKWSSHYQYHLRQHTGERPYVCQECGKSFKNTSCLRRHSQLHSGLRPHACSVCGKAFSQTSNLKQHERTHSGERPFQCSQCHKSFTHSSNLQLHLRTHSSHKDFKCQHCGKEFVMLSYLQRHLRTHLRTSAGDVACTKEAGKVVKGSGASETATLNVNLNVPGGLTSLFPTDSNSTLILSPPNLDIPPNTSQNYFMIQTTSGLQLIPLSNPTPTQPAPPPPPPPPPQNFLLLQCQSNNGNQPSLILVPTASSTNTLPTPSEPQTLPLVQTIPAMPQVLAAPQIQIQPFQPVQTQQRFILTNNNAPLITPQPQNTSTIARPILGSLARSRKGATRRGRKPKAATQKSPSALHTTPVKQPLRLSSAGSTSPTISSVTSAASVKTMFPKLNANNPPAVLPVSTCQVPESPSVPSVSIMSVTPNSTLTNSSPMLSSDPESVAVKKAVKEISREHFVLCLKKEMENGEQGDGMEVKVEMGGENDAERSYVLQIEGEHQEEGENGEGGEKSYVLRFQTEGECEGEAGKDKTGMVSLNLLQEWTEQSEGHGAANAEGNVDVEKSFVLHFQTEPQNEDDIQPSSGFIGGPGEDLSLSCHPGQALVPLEGQDVVFELGDETKIDGSTGAGDSVQMIALIEGEGNSSGARGSFKGAVGANSGQMEGIFQLEGGEGIVIIEVSTSSLRESGIEAADVGHALVEGTEENQTNDAQGGHEVMSEELKVAETESLSTSEIGLIGT", "length": 1425, "header": "tr|A0A8M9P879-1|A0A8M9P879_DANRE Isoform 1 of Zinc finger protein 628 isoform X1 OS=Danio rerio OX=7955 GN=znf628 PE=3 SV=2 CANONICAL=A0A8M9P879-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PDH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879/entry#A0A8M9PDH8-1", "sequence": { "sequence": "MANTVATLVVQTELLTSQTPSALSPFPSLLPSVEDGEEDGGKGEEEGKETETVVLTGDLVTSSTPPVTTVAQNPEHPFQCLDCGKSFKWSSRLAHHQRSHNNERPYRCNICPKAFKGSSALLYHQRSHSGEKPYKCDDCGKAFKRSSLLQIHRSVHTGLRTFQCSYCPLTFKWSSHYQYHLRQHTGECPYPCDSCSKAFKNSSSLRRHKNVHLGFKPYVCDVCNKAFSQSTNLRQHMRIHTGERPYICGDCGRSFTHSSNLALHRISHMDGKGKSAGKAGGVGSATREVEVVLTEDLNTVGMSISEMVGLVGGQEGAVGQVFLSHSTPSPATSGPANQNLLPQLTLTSTSSSVTDTDHIHMSKGDTCANVLLFSCGSCNETFSTQIHLEEHQTLHLDSLGPAGGGVVATESCTEADGAGVSLVGATPLLADFEEVVETTTVADSGQGAELLGLDAVRNESGQAQYDLLQTFTASVNQLTSDNSLPAAQATTDCTYCGKTFKTSSGLTRHVAQHSHTPEQRLLAEAEAEAEIVCPSLSLPLPSLKREGEDGEREIHVSLIAVTEEGERRAVKPSAKASGKGSRRGGGSKTSAANNERPYRCSECGKSFKGSSGLRYHMRDHTGERPYRCTECGKSFKRSSLLSIHQRVHTGVRAFQCPYCPLTFKWSSHYQYHLRQHTGERPYVCQECGKSFKNTSCLRRHSQLHSGLRPHACSVCGKAFSQTSNLKQHERTHSGERPFQCSQCHKSFTHSSNLQLHLRTHSSHKDFKCQHCGKEFVMLSYLQRHLRTHLRTSAGDVACTKEAGKVVKGSGASETATLNVNLNVPGGLTSLFPTDSNSTLILSPPNLDIPPNTSQNYFMIQTTSGLQLIPLSNPTPTQPAPPPPPPPPPQNFLLLQCQSNNGNQPSLILVPTASSTNTLPTPSEPQTLPLVQTIPAMPQVLAAPQIQIQPFQPVQTQQRFILTNNNAPLITPQPQNTSTIARPILGSLARSRKGATRRGRKPKAATQKSPSALHTTPVKQPLRLSSAGSTSPTISSVTSAASVKTMFPKLNANNPPAVLPVSTCQVPESPSVPSVSIMSVTPNSTLTNSSPMLSSDPESVAVKKAVKEISREHFVLCLKKEMENGEQGDGMEVKVEMGGENDAERSYVLQIEGEHQEEGENGEGGEKSYVLRFQTEGECEGEAGKDKTGMVSLNLLQEWTEQSEGHGAANAEGNVDVEKSFVLHFQTEPQNEDDIQPSSGFIGGPGEDLSLSCHPGQALVPLEGQDVVFELGDETKIDGSTGAGDSVQMIALIEGEGNSSGARGSFKGAVGANSGQMEGIFQLEGGEGIVIIEVSTSSLRESGIEAADVGHALVEGTEENQTNDAQGGHEVMSEELKVAETESLSTSEIGLIGT", "length": 1393, "header": "tr|A0A8M9PDH8-1|A0A8M9PDH8_DANRE Computationally mapped isoform of Zinc finger protein 628 isoform X2 OS=Danio rerio OX=7955 GN=znf628 PE=3 SV=2 CANONICAL=A0A8M9P879-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 908, "start_aa": "Thr", "end_pos": 908, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr908", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 952, "start_aa": "Thr", "end_pos": 952, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr952", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:492716", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492716", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZI74-1", "protein_name": "Zinc finger protein 628", "gene_name": "Zfp628", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGSHMDMVPASTMEGTGEKPDSTTPAPTPAAQYECGECGKSFRWSSRLLHHQRTHTGERPYKCPDCPKAFKGSSALLYHQRGHTGERPYQCPDCPKAFKRSSLLQIHRSVHTGLRAFTCGLCGLAFKWSSHYQYHLRQHTGERPYPCPDCPKAFKNSSSLRRHRHVHTGERPYSCSICGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHHRTHSPAPSPAPAPAPDPTPTGETSRAGTKVLVSDAYLQPRSPPEPPAPPPQPPPVVPEFFLAAAETTVELVYRCDGCEQGFSSEELLLEHQPCPGPTVATQPQDVPAELPQADSALQPPPATTGPSNFACLPCGKSFQTVAGLSRHQHSHGAASGQAFRCGSCDGAFPQLASLLAHQQCHVEEAAAGRPPPQAEVAEVTCPQEPVAPATPAPPPPPPAPVSAERPYKCAECGKAFKGSSGLRYHLRDHTGERPYQCGECGKAFKRSSLLAIHQRVHTGLRAFTCGQCGLTFKWSSHYQYHLRLHSGERPYACTECGKAFRNTSCLRRHRHVHTGERPHSCSVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFACPICGRGFVMAAYLQRHLRTHTPATTTSGTTGPAVASQPPTPLAAAPTPLAAQDVHVLPNLQAILSLEVAGGTAQATPPGPVAPSSQTFLLVQTAQGLQLIPSSVQPPTPPPPPPPPKLILLPPASAGGMGNGAARPGPRAVGKAGQGTGVVWFPGPGGLGVQGGGNAGTSGGGQSLIVLQNVGSGETGPQEVSGVQLQPAQEVATVQLQPAQEVTTVQLQPAQEVTTVQLQPLTGQVSNSSGGAVATEAPNLLVVQSGAAEELLTSSGPGEVGDSEASAGMVQDVLFETLQTDEGLQSVLVLSGADGEQTRLCVQEVETLSPGLTEPAATDPSGQKLLIFRSAPAADLLESSSVAGGTTTLQLLAPPAPGPVSAPVGVPVAPPSQMVQVVPAVTGPGVMPPQNLPSIQIVQTLPAVQLVHTF", "length": 1039 }, "evidence": [ { "id": "RGD:2323809", "url": "https://alliancegenome.org/gene/RGD:2323809#orthology", "database": "AGR" }, { "id": "MGI:2665174", "url": "https://alliancegenome.org/gene/MGI:2665174#orthology", "database": "AGR" }, { "id": "HGNC:28054", "url": "https://alliancegenome.org/gene/HGNC:28054#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041111-291", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041111-291#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5EBL2-1", "protein_name": "Zinc finger protein 628", "gene_name": "ZNF628", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSGVMVGSHADMAPASTAEGAGEKPGPAAPAPAAQYECGECGKSFRWSSRLLHHQRTHTGERPYKCPDCPKAFKGSSALLYHQRGHTGERPYQCPDCPKAFKRSSLLQIHRSVHTGLRAFICGQCGLAFKWSSHYQYHLRQHTGERPYPCPDCPKAFKNSSSLRRHRHVHTGERPYTCGVCGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHGAAPAPGTASAAPPPQSREPGKVFVCDAYLQRHLQPHSPPAPPAPPPPPPPVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEHQPCPGPDAAPQPQEAPAEAPKADQPPSPLPQPPPPAAAPAPGFACLPCGKSFRTVAGLSRHQHSHGAAGGQAFRCGSCDGSFPQLASLLAHQQCHVEEAAAGRPPPQAEAAEVTCPQEPLAPAAPVPPPPPSAPASAERPYKCAECGKSFKGSSGLRYHLRDHTGERPYQCGECGKAFKRSSLLAIHQRVHTGLRAFTCGQCGLTFKWSSHYQYHLRLHSGERPYACGECGKAFRNTSCLRRHRHVHTGERPHACGVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFTCPICGRGFVMAAYLQRHLRTHAPANTPPSTTAPAAGPQPPAPLAAARAPPATQDVHVLPHLQATLSLEVAGGTAQAPSLGPAAPNSQTFLLVQTAQGLQLIPSSVQPPTPPPPPAPPKLILLPSSSAGAGGGRARQGPRAVGKAGQGAGVVWLPGPGGLGVQGAASAGASGTGQSLIVLQNVGGGEAGPQEMSGVQLQPLRPAPEVTTVQLQPAQEVTTVQLQPAQEVTTVQLQPAQEVTTVQLQPVAGQLSNSSGGAVATEAPNLLVVQSGAAEELLTGPGPGEAGDGEASTGVVQDVLFETLQTDEGLQSVLVLSGADGEQTRLCVQEVETLPPGLTEPPATGPPGQKLLIIRSAPATELLDSSNTGGGTATLQLLAPPPSGPASGPAGLPGAPASQMVQVVPAGAGPGVMTPQGLPSIQIVQTLPAVQLVHTF", "length": 1059 }, "evidence": [ { "id": "RGD:2323809", "url": "https://alliancegenome.org/gene/RGD:2323809#orthology", "database": "AGR" }, { "id": "MGI:2665174", "url": "https://alliancegenome.org/gene/MGI:2665174#orthology", "database": "AGR" }, { "id": "HGNC:28054", "url": "https://alliancegenome.org/gene/HGNC:28054#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041111-291", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041111-291#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CJ78-1", "protein_name": "Zinc finger protein 628", "gene_name": "Znf628", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSHVDMAPASTTEGTGEKPGPTAPAPTPAAQYECGECGKSFRWSSRLLHHQRTHTGERPYKCPDCPKAFKGSSALLYHQRGHTGERPYQCPDCPKAFKRSSLLQIHRSVHTGLRAFTCGQCGLAFKWSSHYQYHLRQHTGERPYPCPDCPKAFKNSSSLRRHRHVHTGERPYTCGICGKSFTQSTNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHHRTHGPAPGPAPAPAPPGETSRADTKVLVSDAYLQPRSPPEPPAPPPQPPPVVPELFLAAAETTVELVYRCDGCEQGFSSEELLLEHQPCPGPPVATQSQDVPAELPQADSALPQPPPATPGPPNFACLPCGKSFRTVAGLSRHQHSHGAASGQAFRCGSCDGAFPQLASLLAHQQCHVEEAAAGRPPPQAEVAEVTCPQEPVAPATPAPPPPPPPAPVVSAERPYKCAECGKAFKGSSGLRYHLRDHTGERPYQCGECGKAFKRSSLLAIHQRVHTGLRAFTCGQCGLTFKWSSHYQYHLRLHSGERPYACTECGKAFRNTSCLRRHRHVHTGERPHSCSVCGKSFAQTSNLRQHQRVHTGERPFRCPLCPKTFTHSSNLLLHQRTHSAERPFACPICGRGFVMAAYLQRHLRTHTPATTTSGTTGSAVASQPPAPLAAAPTPLAAQDVHVLPNLQATLSLEVAGGTAQPTPPGPAAPSSQTFLLVQTAQGLQLIPSSVQSPTPPPPPPPPKVILLPPASAGGPGSGAARPGPRSVGKAGQGTGVVWFPGPGGLGLQGGANAGASGGGQSLIVLQNVGSGETGPQEVSGVQLQPAQEVATVQLQPAQEVTTVQLQPAQEVTTVQLQPLTGQVSNSNGGAGTTEAPNLLLVQSGATEELLTGPGPGEVGDSEAGAGVVQDVLFETLQTDEGLQSVLVLSGADGEQTRLCVQEVETLSPGLAEPAATGPSGQKLLIIRSAPATDLLENSSVAGGTTTLQLLAPSAPGPVSAPVGVPVAPPSQMVQVVPAVAGPGVMAPQNLPSIQIVQTLPAVQLVHTF", "length": 1038 }, "evidence": [ { "id": "RGD:2323809", "url": "https://alliancegenome.org/gene/RGD:2323809#orthology", "database": "AGR" }, { "id": "MGI:2665174", "url": "https://alliancegenome.org/gene/MGI:2665174#orthology", "database": "AGR" }, { "id": "HGNC:28054", "url": "https://alliancegenome.org/gene/HGNC:28054#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041111-291", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041111-291#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P879", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P879", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P879", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P879", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P879", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P879", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879" } ], "pmid": "" }, { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P879", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1007, "end_pos": 1009, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1114, "end_pos": 1116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1119, "end_pos": 1121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1329, "end_pos": 1331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1391, "end_pos": 1393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 458, "end_pos": 460, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 725, "end_pos": 727, "annotation": "n_glycosylation_sequon" }, { "start_pos": 868, "end_pos": 870, "annotation": "n_glycosylation_sequon" }, { "start_pos": 883, "end_pos": 885, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P879", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P879" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 105, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 908, 952 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1007, "end_pos": 1009 }, { "start_pos": 1114, "end_pos": 1116 }, { "start_pos": 1119, "end_pos": 1121 }, { "start_pos": 1329, "end_pos": 1331 }, { "start_pos": 1391, "end_pos": 1393 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 379, "end_pos": 381 }, { "start_pos": 458, "end_pos": 460 }, { "start_pos": 526, "end_pos": 528 }, { "start_pos": 725, "end_pos": 727 }, { "start_pos": 868, "end_pos": 870 }, { "start_pos": 883, "end_pos": 885 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P8K6-1", "uniprot_ac": "A0A8M9P8K6", "uniprot_id": "A0A8M9P8K6_DANRE", "mass": { "chemical_mass": 32228.0, "monoisotopic_mass": 32228.0 }, "refseq": { "ac": "XP_009290935", "name": "1-phosphatidylinositol phosphodiesterase-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290935" }, "gene_names": [ { "name": "LOC100331378", "type": "recommended", "evidence": [ { "id": "A0A8M9P8K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8K6" } ] }, { "name": "LOC100331378", "type": "synonym", "evidence": [ { "id": "XP_009290935", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290935" } ] } ], "protein_names": [ { "name": "1-phosphatidylinositol phosphodiesterase-like", "type": "synonym", "evidence": [ { "id": "XP_009290935", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290935" }, { "id": "A0A8M9P8K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8K6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009290935", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290935" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8K6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8K6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100331378", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8K6", "locus": {} } ], "crossref": [ { "id": "cd08586", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08586", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100331378", "url": "https://www.ncbi.nlm.nih.gov/gene/100331378", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100331378", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331378", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ENYAIDW", "url": "https://omabrowser.org/oma/group/ENYAIDW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P8K6", "url": "https://www.orthodb.org/?gene=A0A8M9P8K6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13593", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13593", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13593:SF147", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13593:SF147", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009290935", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290935", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P8K6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8K6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P8K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8K6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGAPMKTLCIFVLLLHKSAQQHVFNDQETLSLPTNYKTDWMETLDGNMFISNITIPGTHDTMALHGGAAAECQSWSLENQLLAGIRYLDLRVSGNNLKVVHGVISQHTTFADVLNIVKGFLSQHKSETVLLRVKLESKGPFPDDVANQLKNDPGCWVNNEIPQLEDVRGKIVFVQKKNFKLGVPLLETDKKGDYKVGNVEKKKAKIIEHLKQALEPCEVKAVVLNYSSGTGWPLGRLDRTPKNVAKKINPWLYSHLEGASKENIKLCFGVIAMDFPGLDLIQLIISFNK", "length": 289, "header": "tr|A0A8M9P8K6-1|A0A8M9P8K6_DANRE Isoform 1 of 1-phosphatidylinositol phosphodiesterase-like OS=Danio rerio OX=7955 GN=LOC100331378 PE=4 SV=1 CANONICAL=A0A8M9P8K6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P8K6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8K6/entry#A0A8M9P8K6-1", "sequence": { "sequence": "MGAPMKTLCIFVLLLHKSAQQHVFNDQETLSLPTNYKTDWMETLDGNMFISNITIPGTHDTMALHGGAAAECQSWSLENQLLAGIRYLDLRVSGNNLKVVHGVISQHTTFADVLNIVKGFLSQHKSETVLLRVKLESKGPFPDDVANQLKNDPGCWVNNEIPQLEDVRGKIVFVQKKNFKLGVPLLETDKKGDYKVGNVEKKKAKIIEHLKQALEPCEVKAVVLNYSSGTGWPLGRLDRTPKNVAKKINPWLYSHLEGASKENIKLCFGVIAMDFPGLDLIQLIISFNK", "length": 289, "header": "tr|A0A8M9P8K6-1|A0A8M9P8K6_DANRE Isoform 1 of 1-phosphatidylinositol phosphodiesterase-like OS=Danio rerio OX=7955 GN=LOC100331378 PE=4 SV=1 CANONICAL=A0A8M9P8K6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100331378", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331378", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8K6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8K6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8K6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8K6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 225, "end_pos": 227, "annotation": "n_glycosylation_sequon" }, { "start_pos": 52, "end_pos": 54, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P8K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8K6" }, { "id": "SM00148", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00148" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidylinositol-specific phospholipase C X", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 176, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 225, "end_pos": 227 }, { "start_pos": 52, "end_pos": 54 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P8R0-1", "uniprot_ac": "A0A8M9P8R0", "uniprot_id": "A0A8M9P8R0_DANRE", "mass": { "chemical_mass": 114848.0, "monoisotopic_mass": 114848.0 }, "refseq": { "ac": "XP_021327227", "name": "protein NLRC3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327227" }, "gene_names": [ { "name": "LOC103910467", "type": "recommended", "evidence": [ { "id": "A0A8M9P8R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R0" } ] }, { "name": "LOC103910467", "type": "synonym", "evidence": [ { "id": "XP_021327227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327227" } ] } ], "protein_names": [ { "name": "Protein NLRC3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P8R0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R0/entry#names_and_taxonomy" } ] }, { "name": "protein NLRC3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021327227", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327227" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021327227.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021327227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327227" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8R0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC103910467", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R0", "locus": {} } ], "crossref": [ { "id": "A0A8M9P8R0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P8R0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08321", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08321", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "103910467", "url": "https://www.ncbi.nlm.nih.gov/gene/103910467", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:103910467", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910467", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021327227", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327227", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P8R0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P8R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JAN9", "url": "https://www.uniprot.org/uniprotkb/A0AC58JAN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JAN9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JAN9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANVKQLLKNSLDELREAELKEFQWCIINDYRDISKAEMENADRLKTVDKLASCFGPERAVKITVDILRKIKQNQLAEELENTQKQGAASEDCKTPPFDYTNISYELKKKLKEEYEQILLGNSQTGHQKYLDDIYTDLYMVENKTGGRENDHEVIQMELNHNQQKAKEKPLKCNDMFKVQPDTGRQNKRVLTLGIAGVGKTVSVNKFILDWADGKDNQEIVFIFPLPFRRLNLIEDEKYSLIGLLNKYFLSRPGGQLSSLPEEQGKVMFIFDGLDEYRFELNFKEEDGFTDVDKEMRVSKIVTHLLKRQLLCSSLIWITSRPAAASLIPQTYIDQVTEVRGFNDEQKEQYFIKNSSPEVAGNIICHIKKSRSLHIMCHIPVFCWISLTVLQPLLGQESNEKTPTTLTEMYTSYLLSQKQQMKEKYRNDSEPEVNAWSFDDIVLKLGKLAFIQLQKGQLIFYKTDLEKCGLDVKEGSVFSGLCTRMFQEENPISGEQVYSFVHLSVQEFIAALYVFFTYNDKKANLFLDSRKKELTWKLSTKTLFKLHKDAVEKTLQSKNGHLDLFLRFLLGLSLESNQSDQSGLKKLLPGLKCKTENIKDTTDYIKEKIEEEKSAERTINLFHCLNELKDDFVEELQKSLSSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQSCNLTVQCCKSLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGKKRITAGLHKYACFLTLDPNTAHTRLILSEENREVKRVEVDQSYPDHPDRFDVHPQVLCRESVCGRCYWEIDWSGDNHSVWISVSYKSIRRKGAGVECLFGCTAQSWSLLCSPSKFSFRHNNTWTDLPVERLSSTIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLWPGFAVYSGSSVKLS", "length": 1005, "header": "tr|A0A8M9P8R0-1|A0A8M9P8R0_DANRE Isoform 1 of Protein NLRC3 isoform X1 OS=Danio rerio OX=7955 GN=LOC103910467 PE=4 SV=2 CANONICAL=A0A8M9P8R0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P8R0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R0/entry#A0A8M9P8R0-1", "sequence": { "sequence": 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"length": 1005, "header": "tr|A0A8M9P8R0-1|A0A8M9P8R0_DANRE Isoform 1 of Protein NLRC3 isoform X1 OS=Danio rerio OX=7955 GN=LOC103910467 PE=4 SV=2 CANONICAL=A0A8M9P8R0-1" }, "locus": {} }, { "isoform_ac": "A0AC58JAN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R0/entry#A0AC58JAN9-1", "sequence": { "sequence": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P8R4-1", "uniprot_ac": "A0A8M9P8R4", "uniprot_id": "A0A8M9P8R4_DANRE", "mass": { "chemical_mass": 33639.0, "monoisotopic_mass": 33639.0 }, "refseq": { "ac": "XP_021327232", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327232" }, "gene_names": [ { "name": "LOC110438637", "type": "recommended", "evidence": [ { "id": "A0A8M9P8R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R4" } ] }, { "name": "LOC110438637", "type": "synonym", "evidence": [ { "id": "XP_021327232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327232" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P8R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021327232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327232" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021327232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327232" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438637", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R4", "locus": {} } ], "crossref": [ { "id": "A0A8M9P8R4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P8R4", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438637", "url": "https://www.ncbi.nlm.nih.gov/gene/110438637", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": 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"database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021327232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327232", "database": "RefSeq", "categories": [ 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"MASIKEESEDLKIETFTVKQEDPEEQTELMVLKEETEDLNEREENQFEKHQDLLTDEKSTETTSPHKRAQKTKSNDDLTCCQCGKSFTLKHNLEAHMRIHTGEKPFSCDQCGKSFTQKSKIKVHMRVHTRERPYTCPECGKSFRQKQHLKLHIRIHTGEKPFACQQCGNSFTQIQALQNHMGIHTREKPYICTQCGKNFKCKSYLDSHIRTHTGEKPYKCGQCGKSYKQRANLSHHMKRHSREQGVFTFIWIGQSRELTGKCGEQREGKDWHRTTRRNQTRAATSTGMHVSTH", "length": 293, "header": "tr|A0AC58JEV3-1|A0AC58JEV3_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC110438637 PE=3 SV=1 CANONICAL=A0A8M9P8R4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110438637", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438637", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R4" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R4" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8R4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P8R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8R4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 105, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", 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"n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P8V5-1", "uniprot_ac": "A0A8M9P8V5", "uniprot_id": "A0A8M9P8V5_DANRE", "mass": { "chemical_mass": 337338.0, "monoisotopic_mass": 337338.0 }, "refseq": { "ac": "XP_009299854", "name": "zinc finger ZZ-type and EF-hand domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299854" }, "gene_names": [ { "name": "zzef1", "type": "recommended", "evidence": [ { "id": "A0A8M9P8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8V5" } ] }, { "name": "zzef1", "type": "synonym", "evidence": [ { "id": "XP_009299854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299854" } ] } ], "protein_names": [ { "name": "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8M9P8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8V5/entry#names_and_taxonomy" } ] }, { "name": "zinc finger ZZ-type and EF-hand domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_009299854", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299854" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009299854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299854" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8V5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8V5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zzef1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8V5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041222-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041222-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd02249", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02249", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd02343", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02343", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "566682", "url": "https://www.ncbi.nlm.nih.gov/gene/566682", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566682", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566682", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RPTPPCE", "url": "https://omabrowser.org/oma/group/RPTPPCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P8V5", "url": "https://www.orthodb.org/?gene=A0A8M9P8V5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22772", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22772", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22772:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22772:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00569", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00569", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009299854", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299854", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P8V5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P8V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041222-2", "url": "https://zfin.org/ZDB-GENE-041222-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGNAESGCGAGSGDEEDVETESPVFAEGSPASAATGTRAGSGGGGGGGGAGGAAAAGSAGPGRSGRGSANPPAPSHGLPTPEALLEQVKLREAAARMSDSWVAISESVLARNESALVRWLEERLSRGEESVTLEQFCEMLESRDAARDECEEAFGQFDAEGDGIVDVENMLMALRNSNGANLQGELSHVIRQLQACSLTPGFVDIFSKSKDRLKAHASKILKFLHRNRIPSNVIPFPVLDGYNSICTMRTSVVQDFLDYLLQKEKDLDIQYRAELNHDPDVDKVKVVTQCFSFIEASSNNTDVNKLTNGETVSFWQSDGSARSHWIRLKMKPDIVLRRLAIAVASNDHSYMPQLVSIAVGKNRRSLQEIRDVRIPSNITGYVPLLENANISHPYIQINIKRCLSDGCDTRIHGLKTMGYQITKSKEVSVSDASAIWYLSLLTSLVTASMETNPVLAQTVLQSTQKALQHMPPLSLTPSSTEFPKFFSANILEEVDGFLLRIANCCVSPEAELTLLAFALARGSVAKVLISLSGICGHLDSEYRASSLLASMSSVRLRLLHRNGKPLQLHLMACDVKSKEEKSGPENMLTEPNTGDGFLTENGKRKASVILSTENQSCFQVTQIKIKVRKGAIGAKCGLVFAYNDCEVFDADKHFKRFKKYDSWDYKDYKEFVQDSTRITESSEEEPIGWFEVEEDWNDVDIKLQQCRVSKFLMVKFLCARQDTAERLGVQQLIFSGYLCPDSERMEDVEDLSAQAEGSDSGLVTGLALMKKTLYFIQQLTRDMDVSLSKQKTLLDFSDLNLLLFWDFYRKLRSIEGEEAIKTRVLLLQLLQNCFPMLPSPTESQPSDLSASASASPSGSSDVDPAEAVGELCRHLCQVVDGPEGETAAEKALRKEAVKAILNGAAIFYPDKQSRRDKLFHMMKNITEENQPESVKLTFESLCSYFSDQDPKGLLMLPPKGAPSDFDISPVLSVMDTLLIVASRECEVLMSESSGGSIWRVLLSLFWALQGSLLSWCFLQLKGGTATSSDLAREILLKYVEQFLSGTRDILIPLTKSFSGADIMKKLSGSILAMATRQLTIFLLELCALDIPHCVLLKRFYPISDLLKNMSSDTDDIFSKVDLEGCQQPQQPVVLRTWQMESPHNYENSRHETTVFVCPGATSFEVEFDARCETEKRYDYLEFTDARGGKVRYDMKVGTEKWPKKVTFKAGPQLQFLFHSDSSNNEWGYKFTVTAYGLPDVTVSWTSDLQLLVSRLMGRLASRTMALKSPYEIRGVKELPATLMNHILSCPLWKPVFRHGLSGLPGEQKLALASPEASQEDPAPLGDELVEFLKEFARWDPSQDSSDGRTELMRTLLVNCKKQLIRNEIASGLKVDQAVNAIWAAMVYHTPALHPCLKSFVAKNGQSGLSEDLVQVYTLADGIRTWMLEMKQRYLMGKMNGVEEKDEGQNEVTMESLAEVCISRSLFLFQFSPSGGTSAPQDQETSRPEDIACAAPLLRSISTSEGDFQPSPSLSISQTPHGAEAVTSPVSASRERTQDQSFSASGDAGASGSISSQGATGSSESLQSQTGEPLSPSVFPRKAPFSRGRLRLLSLRSMEEPRMAPPVKERFPILKHILSFMKDMVINESSVLQTLALKKAQAVSVCEVLELVQQCILTLGKPHLFQAPCILFLQELLACQKDFTNYFSQLVGSGQEMRERVRHSYHQLVLMLVEAVQGFSALNEKVLLPALSCVQTCLLHLLDMSWEAEDLSLFLDIKLPDLLLAMSQENISVHDIAISQWTEEDEIADYERNCEWMDECLDGMFEKWFDKISQASVEDKRKMHMFIARYCDLLNVEISCDGCERIAPWHRYRCLQCTDMDLCKTCFLSGAKPEGHEDDHEMVNMEYACDHCQGLIVGSRINCNVCEDFDLCFGCYNAKKYPDSHLPTHRITVYPMVTIRISDRHRLIQPYIHNYSWLLFAALALFTSELISEKAQDGESLDDVTLGNASALQTQCFDIIKECLLKGQTGKGLRASALLSLLSSNESATVSELCPATAGSSQDISSTDTSSLPSSTTAICSPPLPRDRGGGEGDEKRRRKLVSQDTSDSSCASQTPSVSSEDTLSPGVRGSESSGDTITSPTSENLDAYKEQEEKTARGPLQEHVFAECSRERILGLLAAMLPATKPGSPLSLSSLSPILPLLFRVVISNAGCLNETYHLTLGLLGQLLLRICPAEADAAVTEALTDKFELLNLGDGAALDVAGWKTTQLLFSLGAVCLDSRIGLDWACSVADILRNLNVSSQWCTVLASFTDHCILQLPQHLKRTNLFTLLVLVGFPEVLCMGTQAVFIDNANEQHNMILLKHFTEKNRAAVVDVKTRKRRTVKDYQLVQAHESSSRNDSESHEGQAVSPNSAHLSHYLKNFTSIVSFLLQTGVESSAQDAVEATWVLSLALKGLYNTLKKHGVDQAQEALQGSGLMQLLVRKCSKGTGFSKMWLLRDLEILSIMLYSSKREIHSMAEDADTETDGEKEREKEQDSDHSSCCADDADPNRPDPLEGLDEETKICFQITHDALNAPLHILRAMYELQMKRTDSFFLEVQKRFDGDAIKTDETIRTLAQKWQPSKRPRSDERSTKAVDTDIIIVPCVSKPTRCERATEETNVVTQKLITNTESDLQLSYAKQRRTKSSALLHKELDARSNKAVRQYLFKVNEAIAILYARHVLATLLADWPSDTPIREEDLELSGASHMAYILDMLMQLEERPMWEKILQKVLRGCSQSMLGNLSLTACQFMEEPGMAVQVRESKHPYDNNTNFEDKVHIPGAIFLSVKFDSRCHTEEGCDELLMASSSDFLQDLHTFSGSHQKWTDFEIPGDTLYFRFISDMSNTEWGYKFTVTGGHRGRFQTGFEILKQMLADEQALTHLPLPDIWEWQVGVACRQTGNQRLKAVHLLLRLLQCPSQWACDLTLLRPLWQLFTTMESGLCQDPTSITVLLPLHRALTELFFIAEAKAMEQNVLQEYLLALTTNEQLVVRTAQALKNIAAISLAINYPNKSTKQLNLSP", "length": 3038, "header": "tr|A0A8M9P8V5-1|A0A8M9P8V5_DANRE Isoform 1 of Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Danio rerio OX=7955 GN=zzef1 PE=1 SV=1 CANONICAL=A0A8M9P8V5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P8V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8V5/entry#A0A8M9P8V5-1", "sequence": { "sequence": "MGNAESGCGAGSGDEEDVETESPVFAEGSPASAATGTRAGSGGGGGGGGAGGAAAAGSAGPGRSGRGSANPPAPSHGLPTPEALLEQVKLREAAARMSDSWVAISESVLARNESALVRWLEERLSRGEESVTLEQFCEMLESRDAARDECEEAFGQFDAEGDGIVDVENMLMALRNSNGANLQGELSHVIRQLQACSLTPGFVDIFSKSKDRLKAHASKILKFLHRNRIPSNVIPFPVLDGYNSICTMRTSVVQDFLDYLLQKEKDLDIQYRAELNHDPDVDKVKVVTQCFSFIEASSNNTDVNKLTNGETVSFWQSDGSARSHWIRLKMKPDIVLRRLAIAVASNDHSYMPQLVSIAVGKNRRSLQEIRDVRIPSNITGYVPLLENANISHPYIQINIKRCLSDGCDTRIHGLKTMGYQITKSKEVSVSDASAIWYLSLLTSLVTASMETNPVLAQTVLQSTQKALQHMPPLSLTPSSTEFPKFFSANILEEVDGFLLRIANCCVSPEAELTLLAFALARGSVAKVLISLSGICGHLDSEYRASSLLASMSSVRLRLLHRNGKPLQLHLMACDVKSKEEKSGPENMLTEPNTGDGFLTENGKRKASVILSTENQSCFQVTQIKIKVRKGAIGAKCGLVFAYNDCEVFDADKHFKRFKKYDSWDYKDYKEFVQDSTRITESSEEEPIGWFEVEEDWNDVDIKLQQCRVSKFLMVKFLCARQDTAERLGVQQLIFSGYLCPDSERMEDVEDLSAQAEGSDSGLVTGLALMKKTLYFIQQLTRDMDVSLSKQKTLLDFSDLNLLLFWDFYRKLRSIEGEEAIKTRVLLLQLLQNCFPMLPSPTESQPSDLSASASASPSGSSDVDPAEAVGELCRHLCQVVDGPEGETAAEKALRKEAVKAILNGAAIFYPDKQSRRDKLFHMMKNITEENQPESVKLTFESLCSYFSDQDPKGLLMLPPKGAPSDFDISPVLSVMDTLLIVASRECEVLMSESSGGSIWRVLLSLFWALQGSLLSWCFLQLKGGTATSSDLAREILLKYVEQFLSGTRDILIPLTKSFSGADIMKKLSGSILAMATRQLTIFLLELCALDIPHCVLLKRFYPISDLLKNMSSDTDDIFSKVDLEGCQQPQQPVVLRTWQMESPHNYENSRHETTVFVCPGATSFEVEFDARCETEKRYDYLEFTDARGGKVRYDMKVGTEKWPKKVTFKAGPQLQFLFHSDSSNNEWGYKFTVTAYGLPDVTVSWTSDLQLLVSRLMGRLASRTMALKSPYEIRGVKELPATLMNHILSCPLWKPVFRHGLSGLPGEQKLALASPEASQEDPAPLGDELVEFLKEFARWDPSQDSSDGRTELMRTLLVNCKKQLIRNEIASGLKVDQAVNAIWAAMVYHTPALHPCLKSFVAKNGQSGLSEDLVQVYTLADGIRTWMLEMKQRYLMGKMNGVEEKDEGQNEVTMESLAEVCISRSLFLFQFSPSGGTSAPQDQETSRPEDIACAAPLLRSISTSEGDFQPSPSLSISQTPHGAEAVTSPVSASRERTQDQSFSASGDAGASGSISSQGATGSSESLQSQTGEPLSPSVFPRKAPFSRGRLRLLSLRSMEEPRMAPPVKERFPILKHILSFMKDMVINESSVLQTLALKKAQAVSVCEVLELVQQCILTLGKPHLFQAPCILFLQELLACQKDFTNYFSQLVGSGQEMRERVRHSYHQLVLMLVEAVQGFSALNEKVLLPALSCVQTCLLHLLDMSWEAEDLSLFLDIKLPDLLLAMSQENISVHDIAISQWTEEDEIADYERNCEWMDECLDGMFEKWFDKISQASVEDKRKMHMFIARYCDLLNVEISCDGCERIAPWHRYRCLQCTDMDLCKTCFLSGAKPEGHEDDHEMVNMEYACDHCQGLIVGSRINCNVCEDFDLCFGCYNAKKYPDSHLPTHRITVYPMVTIRISDRHRLIQPYIHNYSWLLFAALALFTSELISEKAQDGESLDDVTLGNASALQTQCFDIIKECLLKGQTGKGLRASALLSLLSSNESATVSELCPATAGSSQDISSTDTSSLPSSTTAICSPPLPRDRGGGEGDEKRRRKLVSQDTSDSSCASQTPSVSSEDTLSPGVRGSESSGDTITSPTSENLDAYKEQEEKTARGPLQEHVFAECSRERILGLLAAMLPATKPGSPLSLSSLSPILPLLFRVVISNAGCLNETYHLTLGLLGQLLLRICPAEADAAVTEALTDKFELLNLGDGAALDVAGWKTTQLLFSLGAVCLDSRIGLDWACSVADILRNLNVSSQWCTVLASFTDHCILQLPQHLKRTNLFTLLVLVGFPEVLCMGTQAVFIDNANEQHNMILLKHFTEKNRAAVVDVKTRKRRTVKDYQLVQAHESSSRNDSESHEGQAVSPNSAHLSHYLKNFTSIVSFLLQTGVESSAQDAVEATWVLSLALKGLYNTLKKHGVDQAQEALQGSGLMQLLVRKCSKGTGFSKMWLLRDLEILSIMLYSSKREIHSMAEDADTETDGEKEREKEQDSDHSSCCADDADPNRPDPLEGLDEETKICFQITHDALNAPLHILRAMYELQMKRTDSFFLEVQKRFDGDAIKTDETIRTLAQKWQPSKRPRSDERSTKAVDTDIIIVPCVSKPTRCERATEETNVVTQKLITNTESDLQLSYAKQRRTKSSALLHKELDARSNKAVRQYLFKVNEAIAILYARHVLATLLADWPSDTPIREEDLELSGASHMAYILDMLMQLEERPMWEKILQKVLRGCSQSMLGNLSLTACQFMEEPGMAVQVRESKHPYDNNTNFEDKVHIPGAIFLSVKFDSRCHTEEGCDELLMASSSDFLQDLHTFSGSHQKWTDFEIPGDTLYFRFISDMSNTEWGYKFTVTGGHRGRFQTGFEILKQMLADEQALTHLPLPDIWEWQVGVACRQTGNQRLKAVHLLLRLLQCPSQWACDLTLLRPLWQLFTTMESGLCQDPTSITVLLPLHRALTELFFIAEAKAMEQNVLQEYLLALTTNEQLVVRTAQALKNIAAISLAINYPNKSTKQLNLSP", "length": 3038, "header": "tr|A0A8M9P8V5-1|A0A8M9P8V5_DANRE Isoform 1 of Zinc finger ZZ-type and EF-hand domain-containing protein 1 OS=Danio rerio OX=7955 GN=zzef1 PE=1 SV=1 CANONICAL=A0A8M9P8V5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "A0A8M9P8V5", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M9P8V5" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0A8M9P8V5", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M9P8V5" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:566682", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566682", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AB20-1", "protein_name": "Zinc finger ZZ-type and EF-hand domain containing 1", "gene_name": "ZZEF1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGTAASHSSEEEEEGAEEGMEAAAQPGDPFPAASPAPPLPPAEVLLEQARLREATARLREAALPESLVSRHHGALVRWLEERLSRGDEAVSLEQFCEVLESVSRLTAGSRGESEEAFAQFDAEGDGTVDVENMLEALKNSSGANLQGELSHVIRQLQACSLVPGFIDIFSESKERLGLHASMILRFLHRNRISSTAIPYPVLEYFNNICMMRSSVLKDSLDRLLLKEREYPSDLNGNEESDKLKSVTKCYTHIETSSNSADIDKMTNGETTSFWQSDGSARSHWIRLKMKPDVVLRHLSIAVAANDQSYMPQQVTVAVGRNASSLQEVRDVHIPSNITGYVTLLENANISQMYVQINIKRCLSDGCDTRIHGLRAIGYQRVKKVGVSVCDASAIWYWSLLTSLVTASMETNPAFVHTILQNTQKALQHMPPLSLTPSSTDFSSFLSPNVLQEVDSFLIRITSCCTTPDVELTLLAFALARGSVAKVISSLCTITDHLDTPYKASSLIASMATVRQNLLYKYGKPLRLTLQACDVKGKEDKSGPENLLVEPWTGDGFLTETGKTRASIILSTGTESSFQVTQIRIKVRRGAIGAQCGLVFAYNSASEKFHAEEHFKRFESYDKWKLKDFKQFLKNRSGSSSDELGDDDPIGWFEVEEEWDEVDVRMQQCRVAQYLMIKFLCTRQDTAERLGVQGLNVLGYLRPMREEPSRSMHCLQCRKTDDETVCGTTLLLKTLHFIQQLAQDLVQQKESGLKCKSYLDFTDLDLQLFWNFYNKLHQNPREECIFAQTLLLQLLQSCFSVFTGDNKTSKPQETLQGRTPGHTKAAEDLYRHLCEVVDMGDTNFMPVKMLKQEVKNTLLSGAAIFFPDRQTRRNQLFAMMKNITEQEHKQSVHLAFRSLCTHFSDQDPGGLLLLPEKGVSANFDISEVLSVMDTLLLVAARECEMMMLDVAQQESGTVLSSLFWSVQGSLLSWCYLQLKGSDSSAKDLAVEILKNYVGQFLTNVRMILQSLLSQYSGKTIVEKISNSVFAMATRQLVIFLLDFCTLDIPYCTLLQEFSTLVEPLKKLCSEPHKMEIESWQQEQPVVLRTWTVESPHNYENNCHEVSVFLCHGASYFEVEFDEKCETERRYDYLEFTDARGAKTRYDTKVGTEKWPKKVTFKAGPRLQFLFHSDSSNNEWGYKFTVTAYGLPDVAVSWGLDLQLLVCRLMGRLASRSMALKSQRELGSEADLPPLKVTSVLNSPLWKPVFRHQMCPEAEPGASETSRGHQDKKEARSSHQDDCRNFLIDFARSDPAQDFSGQKSELFKGLVQTCRKQTPKTDTVAGSTVDRAVNSTFAALVYLTPALYEKLQKYVNSGGKVPLSDEFAQVYSLADSIRIWMLEMKQKSLMGRGNDTEEKQSTEASEVNPETLAKLCMQKSLLLLNFLPVRAKTKGSTSDSLEAQDGDNVHQYVNDRNQRKSSVVETDFQAAHSSSSSGVTRSVSVEGEQTTQSDTKIKQISDPLQTEEVSAFHSKPSENTALQQEDVPSPPSTPTRKSQFSRGRLRLLSFRSMEEPRAVPTLKEKYPILKSILDFIKDQSLSHESVLKVLALRKSQGQNILEVLRTIRRCLDSLGQPHCFHPPCVLFLLELLACQKDFTNYFGNLEGCGAALHKEIRESYYQLVLFLVNSVKGFSAINDRSLLPALSCVQTTLLHLLDMSWEPTDLSFFVEIQLPQLLMATSQENISIHDSVICQWSEEDEIADYKQNCEWMDECQDIMFESWYEKIAQADPEKQRKMHMFVARYCDLLNVDISCDGCDEIAPWHRYRCLQCNDMDLCKTCFLGGVKPEGHEDDHEMVNMEYACDHCQGVIIGRRMNCNVCDDFDLCYGCYSAKKYSDSHLPTHSITVYPMMTIRISDRQRLIQPYVHNYSWLLFAALTLYSADLANGEEVEGEKLDSQVLSHARILQHQCIQLIGDCLMKAQQGKGLKNLALLCMLPEGESLSENDTASVSPPTDGAPKSHTGDKAGKGKDEKPSTGSFMHSNGKGETLNEIQSPAGDKVQKHGSESDRNAVSAKKAVLRQESELSMEDNITPTVDDCISEDSAQKQAEKVLIPSQEQVFAECSQKRILGLLAAMLPPFKSGSTMSLINLEQILPLMFQVVISNAGHLNETYHLTLGLLGQLILRLKPAEVDAAVAKVLSTKHSLFAAGDPSTVPEGWKTTHLLFSLGAVCLDSRVGLDWASSMADILRSLNSSAQWHSVIAAFTDHCIKQLPFQLKHTNIFTLLVLVGFPEVLCMGTRSVYMDNANEPHNVIILKHFTEKNRAVVVDIKTRKRKTVKDYQLIQKCEQEGSDSQAQLRQYLQHFVLICTHLLQTTIDSSYAEAVEATWVLSLALKGLYRTLKIHGFQEVQDAFLHSGLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEISSLAEREDTELEEREQDQDVEQSIVGPADVEQNKLDPLEGLDEATKICFLMTHDALNAPLHILRAMYELQMKRTESFFLEVQKRFDGDVITTDERIRTLAQKWQPSKRLRLEEQSSKAVDTDMIILPCLSKPVLCDKATEETNPVAQKLITNTESDLQLSYAKQRRTKSSILLHKELDSRSKKAVRDYLYRVNEATAVLYARHVLASLLAEWPDDVAINEEVLDLSGPAHMTYILDMLMQLEEKQLWEKILQKVLLGCNESMLGTMALTACQFMEEPGMAVQVRESKHPYNNNTNFEDKVQIPGAIYLSIKFDSQCNTEEGCDELLMSSSSDFQQDRHSFSGSPQKWNDFELPGDTLYYRFTSDMSNTEWGYKFTVTAGHLGRFQTGFEILKQMLSEERVIPHLPLARIWEWQVGVACRQTGHQRLKAIHLLLKIVQCSAQRDCDLTLLKPLWQLFTHMENNICHDVTKPGILLPLHRALAELFFVTENRVTELGSLQEYLLALNSEDHLHRCTAQALRNIAAISLAINYPNKSTSFWNV", "length": 2974 }, "evidence": [ { "id": "A0A8M9P8V5", "url": "https://omabrowser.org/oma/group/A0A8M9P8V5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZG78-1", "protein_name": "Zinc finger ZZ-type and EF-hand domain containing 1", "gene_name": "Zzef1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNAPSNSSEDEAAAAGGEGWSPHQDWAADSGATPGPGPAAAVLPSAAALLEPARLREAAAALRPAPPCESLVSRHHGALLRWLEERLGRGEESVTLEQFRELLEARGAGCSGEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHVIRQLQACSLVPGFIDIFSESKEGLGTHSSMILRFLHRNRVSSMVIPYPMLDHCNNMCTMRSSVLKDSLDQLLQKEKESPGDLARSPEMDKLKSVTKCYAYIETSSNPADIYRMTNGETSSYWQSDGSARSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRSASDLQEVRDVHIPSNVTGYVTLLENANISQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLHNTQKALQHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSIAKVMSSLCAISDHLDTQYDASSLISSMASVRQSLLLKYGKPLQLTLQACDVKGKEDKSGPENLLVEPWTRDGFLTETGKTRASTIFSAGTESAFQVTQIRIMVRRGGIGAQCGLVFAYNSPSDKFHAEEHFKRFEKYDRWKLQELRQFVKSRIGCSPDDLGEDDPIGWFELEEEWDEADVKLQQCRVAKFLMVKFLCTRQESAERLGVQGLSISGYLRPARAEAEQSILYAHCRRDTENIYGATLLLRTLQFIQQLAHDLVQQKESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECICAQTLLLQLLQSCFSVLQGDPQAVSEEEKPAAQRPEGIQAAKELYTHLCDVVDRADGESMPMEILKQEVRNTLLNGAAIFFPDRQTRRNQLFTMMKNVTEHERKQSLQLTFRSLCTYFSDKDPGGLLLLPEKSDLATMNTSEVLAVMNTLLSVAARECELLMLGRAHGEVGSVLFSLFWSVQGSLLSWCFLQLKSTDAAAKELAMDLIEKYVGQFLASMRVILESLLSQYSGKTIVEKLCNSVFSMAARQLVIFLLDFCTLDVSHCTLLREFSTLTELLKKLCSDPEGGLSKLDVETWQQEQPVVLHTWTKESTHNYENNCHEVSVFVSPGATYFEVEFDERCETEKRYDYLEFTDSRGGKTRYDTKVGTYKWPKKVTFKDGPRLQFLFHSDSSNNEWGYKFTVTAYGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVHQLGSNLAISQAKLTAVLNSPLWKPVFRHQICPELELEASWPTHPHQDGKEVKNIPDDPCRHFLLDFAQSEPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVHSGGKIALPEEFSQVYSLADGIRIWMLEMKQKSLVSMGNDSEEKRGLETAEVNPENLAKECIQKSLLLLKFLPMSKSSKENCDKLVPVDETDRLQPLDRRQRTSSVVEEHFQGSASPTEAATPAADDKSPGLEMQPKLLPSSGPSAAEVSTAEEPSSPSTPTRRPPFTRGRLRLLSFRSMEETRPVPTVKEKYPVLKDVMDFIKDQSLSHESIVKVLSLRKAQAQSILEVLRIIQYCTESLGQPHCFHPPYILFLLELLTCQKDFTNYFGHLEGCGADLHKEIRDTYYQLVLFLVKAIKGFSSINDRSLLPAVSCVQTALLHLLDMGWEPSDLAFFVDIQLPDLLMNMSQENISIHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCDDFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRFIQPYIHNYSWLLFAALALYSAHLTSTEHVDGEQLDPQARGSAATLRSQCMQLVGDCLMKAHQGKGLKALALLGVLPDGDSTSENQALPVTVSIQASEEQLEKKTAQPAEGPADAGLFVPCNGKRATDKEVGPLDCKQKKKAGEDLSIMKDPSCQIQVSDPPASDHVPPGLPDAEHPDRSSQAPMEEKAITPSPEQVFAECSQKRILGLLAAMLPPIKSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLQPAEVDAAVMKVLSAKHNLFATADNAVVPDGWKTTHLLFSLGAVCLDSRVGLDWACSMAEILRSLNNAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGGGQECGTSQAQLSQYSQHFAFIASHLLQTSMDSHCPEAVEATWVLSLALKGLYKTLKTHGFEETHATFLHTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINTLTEHGDLELDERGDQEEELDRPVSSPGEAEQKKLDPLESLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDSFFLEVQKRFDGDELTTDERIRSLAQRWQPSRSLRLEEQSAKAVDTDMIILPCLSRPARSDQATSESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSKRAVRDYLFRVNEATAVLYARHVLASLLAEWPGHVPVSEDILELSGPAHMTYILDMFMQLEEKHQWEKILQKVLQGCRESMLGTMALAACQFMEEPGMEVQVRESKHPYNNNTSFEDKVHIPGAIYLSIKFDPQCNTEEGCDELAMSSSSDFQQDRHNFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPHLPLGKIWEWLVGVACRQTGHQRLKAIHLLLRIVRCCSHSDLCDLGLLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALTELFFVTENRAQELGLLQEYLLALTTEDHLLRCAAQALQNIAAISLAINYPNKATRLWNVEC", "length": 2965 }, "evidence": [ { "id": "RGD:1311189", "url": "https://alliancegenome.org/gene/RGD:1311189#orthology", "database": "AGR" }, { "id": "MGI:2444286", "url": "https://alliancegenome.org/gene/MGI:2444286#orthology", "database": "AGR" }, { "id": "HGNC:29027", "url": "https://alliancegenome.org/gene/HGNC:29027#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041222-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041222-2#orthology", "database": "AGR" }, { "id": "A0A8M9P8V5", "url": "https://omabrowser.org/oma/group/A0A8M9P8V5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43149-1", "protein_name": "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "gene_name": "ZZEF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNAPSHSSEDEAAAAGGEGWGPHQDWAAVSGTTPGPGVAAPALPPAAALLEPARLREAAAALLPTPPCESLVSRHRGALFRWLEERLGRGEESVTLEQFRELLEARGAGCSSEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHIIRQLQACSLVPGFTDIFSESKEGLDIHSSMILRFLHRNRLSSAVMPYPMLEHCNNMCTMRSSVLKESLDQLVQKEKESPGDLTRSPEMDKLKSVAKCYAYIETSSNSADIDKMTNGETSSYWQSDGSACSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRNASDLQEVRDVHIPSNVTGYVTLLENANVSQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLHNTQKALRHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSVAKVMSSLCTITDHLDTQYDASSLILSMASVRQNLLLKYGKPLQLTLQACDVKGKEDKSGPENLLVEPWTRDGFLTETGKTRASTIFSTGTESAFQVTQIRIMVRRGGIGAQCGLVFAYNSSSDKFCAEEHFKRFEKYDKWKLQELRQFVKSRIGCSSDDLGEDDPIGWFELEEEWDEADVKLQQCRVAKYLMVKFLCTRQESAERLGVQGLTISGYLRPARAEAEQSVTCAHCRKDTEESVCGATLLLRTLQFIQQLAHDLVQQKESGLKYKSFLDFAGLDLQIFWNFYSKLKQNPREECVSAQTLLLQLLQSCFSVLQGDVLAASEEEKAPIQSPKGVEAAKELYTHLCDVVDKVDGDSVPMEILKQEVRNTLLNGAAIFFPNRQTRRNHLFTMMNVTEQEHKQSLQLTFRSLCTYFSDKDPGGLLLLPEKNDLAKMNISEVLAVMDTLVSVAARECELLMLSGAPGEVGSVLFSLFWSVQGSLLSWCYLQLKSTDSGAKDLAVDLIEKYVGQFLASMRAILESLFSQYSGKTIVERLCNSVFSMAARQLVIFLLDFCTLDIPHCVLLREFSVLTELLKKLCSGPEGGLRKLDVETWQQEQPVVLHTWTKESAHNYENNCHEVSVFVSPGATYFEVEFDDRCETEKRYDYLEFTDARGRKTRYDTKVGTDKWPKKVTFKAGPRLQFLFHSDSSHNEWGYKFTVTACGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVRQLGSNMVVPQAKMALVLSSPLWKPVFRHQVCPELELEASWPTHPHRNSKEVKNIPDDPCRHFLLDFAQSEPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVNSGGKIALSEEFAQVYSLADGIRIWMLEMKQKSLMSLGNEAEEKHSSEATEVNPESLAKECIEKSLLLLKFLPTGISSKESCEKLETADETSHLQPLNKRQRTSSVVEEHFQASVSPTEAAPPATGDQSPGLGTQPKLPSSSGLPAADVSPATAEEPLSPSTPTRRPPFTRGRLRLLSFRSMEEARLVPTVKEKYPVLKDVMDFIKDQSLSHRSVVKVLSLRKAQAQSILEVLKITQHCAESLGQPHCFHPPFILFLLELLTCQKDFTNYFGHLEGCGADLHKEIRDTYYQLVLFLVKAVKGFSSLNDRSLLPALSCVQTALLHLLDMGWEPNDLAFFVDIQLPDLLMKMSQENISVHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCDDFDLCYGCYAAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSWLLFAALALYSAHLASAEDVDGEKLDPQTRSSATTLRSQCMQLVGDCLMKAHQGKGLKALALLGVLPDGDSSLEDQALPVTVPTGASEEQLEKKAVQGAELSEAGNGKRAVHEEIRPVDFKQRNKADKGVSLSKDPSCQTQISDSPADASPPTGLPDAEDSEVSSQKPIEEKAVTPSPEQVFAECSQKRILGLLAAMLPPLKSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLLPAEVDAAVIKVLSAKHNLFAAGDSSIVPDGWKTTHLLFSLGAVCLDSRVGLDWACSMAEILRSLNSAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGGGQECGDSRAQLSQYSQHFAFIASHLLQSSMDSHCPEAVEATWVLSLALKGLYKTLKAHGFEEIRATFLQTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINALAEHGDLELDERGDREEEVERPVSSPGDPEQKKLDPLEGLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDYFFLEVQKRFDGDELTTDERIRSLAQRWQPSKSLRLEEQSAKAVDTDMIILPCLSRPARCDQATAESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSKRAVRDYLFRVNEATAVLYARHVLASLLAEWPSHVPVSEDILELSGPAHMTYILDMFMQLEEKHEWEKILQKVLQGCREDMLGTMALAACQFMEEPGMEVQVRESKHPYNNNTNFEDKVHIPGAIYLSIKFDSQCNTEEGCDELAMSSSSDFQQDRHSFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPHLPLAKIWEWLVGVACRQTGHQRLKAIHLLLRIVRCCGHSDLCDLALLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALTELFFVTENRAQELGVLQDYLLALTTDDHLLRCAAQALQNIAAISLAINYPNKATRLWNVEC", "length": 2961 }, "evidence": [ { "id": "RGD:1311189", "url": "https://alliancegenome.org/gene/RGD:1311189#orthology", "database": "AGR" }, { "id": "MGI:2444286", "url": "https://alliancegenome.org/gene/MGI:2444286#orthology", "database": "AGR" }, { "id": "HGNC:29027", "url": "https://alliancegenome.org/gene/HGNC:29027#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041222-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041222-2#orthology", "database": "AGR" }, { "id": "A0A8M9P8V5", "url": "https://omabrowser.org/oma/group/A0A8M9P8V5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5SSH7-1", "protein_name": "Zinc finger ZZ-type and EF-hand domain-containing protein 1", "gene_name": "Zzef1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNAPSNSSEDEAAAAGGEGWSPHQDWAADSGTTPGPGPAAAVLPSAAALLEPARLREAAAALRPAPPCESLVSRHHGALLRWLEERLGRGEESVTLEQFRELLEARGAGCSGEQFEEAFAQFDAEGDGTVDAENMLEALKNSSGANLQGELSHVIRQLQACSLVPGFIDIFSESKEGLGIHSSMILRFLHRNRISSMVIPYPMLDHCNNMCTMRSSVLKESLDQLVQKEKESPGDLARSPEMDKLKSVTKCYAYIETSSNPADIYRMTNGETSSYWQSDGSARSHWIRLKMKPDVVLRHLSIAVAATDQSYMPQQVTVAVGRSASDLQEVRDVHIPSNVTGYVTLLENANISQLYVQINIKRCLSDGCDTRIHGLRAVGFQRVKKSGVSVSDASAIWYWSLLTSLVTASMETNPAFVQTVLHNTQKALQHMPPLSLSPGSTDFSTFLSPNVLEEVDSFLIRITSCCSTPEVELTLLAFALARGSIAKVMSSLCTITDHLDTQYDASSLISSMASVRQNLLLKYGKPLQLTLQACDVKGKEDKSGPENLLVEPWTRDGFLTETGKTRASTIFSTGSDSAFQVTQIRIMVRRGGIGAQCGLVFAYNSPSNKFHAEEHFKRFEKYDKWKLQELRQFVKSRIGCSSDDLGEDDPIGWFELEEEWDEADVKLQQCRVAKFLMVKFLCTRQESAERLGVQGLSISGYLRPARAEAEQSILYAHCRRDTENIHGATLLLRTLQFIQQLSHDLMQQKESGLKHKSFLDFAGLDLQIFWKFYSKLKQNRREECICAQTLLLKLLQSCFSVLQGDPQAASEEEKPTAQRSEGIQAAKELYTHLCNVVDKPNGNSMPMEILKQEVRNTLLNGAAIFFPDRQTRRSQLFTMMKSVTEHERKQSLQLTFHSLCTYFSDKDPGGLLLLPEKSDLATMNTSEVLAVMNTLLSVAARECELLMLNRSHGAVGSVLFSLFWSVQGSLLSWCFLQLKSTDAAAKELAMDLIEKYVGQFLASMRVILESLLSQYSGKTIVEKLCNSVFSMAARQLVIFLLDFCTLDVSHCTLLREFSTLTELLKKLCSDPEGGLSKLDVETWQQEQPVVLHTWTKESTHNYENNCHEVSVFISPGATYFEVEFDERCETEKRYDYLEFTDSRGGKTRYDTKVGTYKWPKKVTFKDGPRLQFLFHSDSSNNEWGYKFTVTAYGLPDVAVSWGLDLQLLVSRLMGRLASQCMALKSVHQLGSNMAVSQAKLTSVLNSPLWKPVFRHQICPELELEASWPTHPHKDGKEVKNIPDDPCRHFLLDFAQSEPAQNFCGPYSELFKGFIQACRKQAPKTDIVAGSTIDQAVNATFAALVYRTPDLYEKLQKYVNSGGKIALTEEFSQVYSLADGIRIWMLEMKQKSLLSLGNDSEEKRGLEAAEVNPESLAKECIQKSLLLLKFLPMSKSSKENCDKLETVDETDHLQPLDRRQRTSSVVEEHFQGSASPTEAATPAAGDRSPALEIQPKLLPSSGPCVAEVSTAEEPSPPSTPTRRPPFTRGRLRLLSFRSMEETRPVPTVKEKYPVLKDVMDFIKDQSLSHESVVKVLSLRKAQGQSILEVLRIIQYCTESLGQPHCFHPPYILFLLELLTCQKDFTNYFGHLEGCGADLHREIRDTYYQLVLFLVKAIKRFSSINDRSLLPALSCVQTALLHLLDMGWEPSDLAFFVDIQLPDLLMNMSQENISVHDSVISQWSEEDELADAKQNSEWMDECQDGMFEAWYEKIAQEDPEKQRKMHMFIARYCDLLNVDISCDGCDEIAPWHRYRCLQCSDMDLCKTCFLGGVKPEGHGDDHEMVNMEFTCDHCQGLIIGRRMNCNVCDDFDLCYGCYTAKKYSYGHLPTHSITAHPMVTIRISDRQRLIQPYIHNYSWLLFAALALYSAHLTSTEQVDGEQLDPQARTNAATLRSQCMQLVGDCLMKAHQGKGLKALALLGVLPDGDSTSENQALPVTVSFQASEEQADAGLLVPCNGKRAADTEVRPLDYKQKKKAGEDLSIVKDPSCQTQVSDAPASAHVPPGLPDAEHPEVSAQVLVEEKAITPNPEQVFAECSQKRILGLLAAMLPPIKSGPTVPLIDLEHVLPLMFQVVISNAGHLNETYHLTLGLLGQLIIRLQPAEVDAAVMKVLSAKHNLRVGLDWACSMAEILRSLNNAPLWRDVIATFTDHCIKQLPFQLKHTNIFTLLVLVGFPQVLCVGTRCVYMDNANEPHNVIILKHFTEKNRAVIVDVKTRKRKTVKDYQLVQKGGGQECGTSQSQLSQYSQHFAFIASHLLQTSMDSHCPEAVEATWVLSLALKGLYKTLKAHGFEETHATFLQTDLLKLLVKKCSKGTGFSKTWLLRDLEILSIMLYSSKKEINTLAEHGDLELDERGDQEEELDRPVSSPGEAEQKKLDPLENLDEPTRICFLMAHDALNAPLHILRAIYELQMKKTDSFFLEVQKRFDGDELTTDERIRSLAQRWQPSRSLRLEEQSAKAVDTDMIILPCLSRPARSDQATPESNPVTQKLISSTESELQQSYAKQRRSKSAALLHKELNCKSKRAIRDYLFRVNEATSVLYARHVLASLLAEWPGHVPVSEDILELSGPAHMTYILDMFMQLEEKHQWEKILQKVLQGCRENMLGTMALAACQFMEEPGMEVQVRESKHSYNNNTSFEDKVHIPGAIYLSIKFDPQRNTEEGCDELAMSSSSDFQQDRHNFSGSQQKWKDFELPGDTLYYRFTSDMSNTEWGYRFTVTAGHLGRFQTGFEILKQMLSEERVVPHLALGKIWEWLVGVACRQTGHQRLKAIHLLLRIVQCCSHSDLCDLGLLKPLWQLFTHMEYGLFEDVTQPGILLPLHRALTELFFVTENRAQELGLLQEYLLALTTEDHLLRCAAQALQNIAAISLAINYPNKATRLWNVEC", "length": 2924 }, "evidence": [ { "id": "RGD:1311189", "url": "https://alliancegenome.org/gene/RGD:1311189#orthology", "database": "AGR" }, { "id": "MGI:2444286", "url": "https://alliancegenome.org/gene/MGI:2444286#orthology", "database": "AGR" }, { "id": "HGNC:29027", "url": "https://alliancegenome.org/gene/HGNC:29027#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041222-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041222-2#orthology", "database": "AGR" }, { "id": "A0A8M9P8V5", "url": "https://omabrowser.org/oma/group/A0A8M9P8V5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8V5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8V5" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P8V5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8V5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1108, "end_pos": 1110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1626, "end_pos": 1628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1769, "end_pos": 1771, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1953, "end_pos": 1955, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1987, "end_pos": 1989, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2024, "end_pos": 2026, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2194, "end_pos": 2196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2278, "end_pos": 2280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2378, "end_pos": 2380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2401, "end_pos": 2403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2761, "end_pos": 2763, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2788, "end_pos": 2790, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3028, "end_pos": 3030, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3035, "end_pos": 3037, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 389, "end_pos": 391, "annotation": "n_glycosylation_sequon" }, { "start_pos": 614, "end_pos": 616, "annotation": "n_glycosylation_sequon" }, { "start_pos": 924, "end_pos": 926, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8V5" }, { "id": "PS51284", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51284" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOC", "eco_id": "ECO_0000259", "start_pos": 263, "end_pos": 443, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8V5" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 145, "end_pos": 180, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P8V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8V5" }, { "id": "PS50135", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50135" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZZ-type", "eco_id": "ECO_0000259", "start_pos": 1834, "end_pos": 1889, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1108, "end_pos": 1110 }, { "start_pos": 112, "end_pos": 114 }, { "start_pos": 1626, "end_pos": 1628 }, { "start_pos": 1769, "end_pos": 1771 }, { "start_pos": 1953, "end_pos": 1955 }, { "start_pos": 1987, "end_pos": 1989 }, { "start_pos": 2024, "end_pos": 2026 }, { "start_pos": 2194, "end_pos": 2196 }, { "start_pos": 2278, 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This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. 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"MSQTTRSHGLGYSCPATRPFENEGVHEVGFISSSQPVMRSLPVCHSLARVHNSAAPLEERRVLRSWEPPRGCHDAQSGNDRCLADRVGRHTGGQDSERRVVPHTSLSPHKLFGASHCVESSKTFSAPPAGASCASAVRQHYSCSTYQPPRGDAILQAPRLSSQAFSMEQATFSVVTGNPCPRRSEQGCRPFVKGEPTLRGVASPSSNSGPALEEIRPGRRRSLRLARKRPLSYVLLATGRGCPPRRGRTGSSMAQCAALCVPSSLPNNPNPIQGEGTRLETDPDSTEVAQGSMAGRDNPSSACTAMAPPITYGPPVPSEWGNLPPSSRQGGSLGLARERANLNTLGLSPRVIATIQNARASSTRSLYDCKWRVFEEWCEERRLISYQCSVADILGFLQGLMDCGKSFSTIKVYLAAITACHVGFDGSTAGQHPLIRRFMKGARRSLPVTRRVVPEWDLSMVLDALTHHPFETLEAISLKHLSFKTALLLALASAKRVSDLHALSVHPSCIKFSLSGEKVSLRPNPAFMPKCFPNFSCEGVELSAFHPPPFSSTEDQRLNALCPVRALRAYINRTSSFRRSDQLFISWAPPNRGNPISKQRLSHWLVEAISLAYESKGVRPPGGLRAHSTRGMAASWALFRGVSLQDICAAASWASPHTFVRYYRLDVTQTPVAHSVLGVGSS", "length": 682, "header": "tr|A0A8M9P981-1|A0A8M9P981_DANRE Isoform 1 of Tyr recombinase domain-containing protein OS=Danio rerio OX=7955 GN=LOC103909016 PE=4 SV=1 CANONICAL=A0A8M9P981-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P981-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P981/entry#A0A8M9P981-1", 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This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323078", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323078" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9H3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9H3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "crip3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9H3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-620", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-620", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd09476", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09476", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09477", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09477", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "556515", "url": "https://www.ncbi.nlm.nih.gov/gene/556515", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556515", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556515", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P9H3", "url": "https://www.orthodb.org/?gene=A0A8M9P9H3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46074", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46074", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46074:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46074:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323078", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323078", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P9H3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P9H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-620", "url": "https://zfin.org/ZDB-GENE-130530-620", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTSICPRCDKTVFFAEKVSSLGKNWHRFCLKCERCSKILSPGGHAEHDGLPYCHKPCYGTLFGPKGVNIGGAGSYIYDTPPQTPVNKTCNSPSEGSPTTPWTTSQINFNQPKAATAPARMFAGETYLCPGCGKAVYFAEKVMSLGRNWHRPCLRCVRCKKTLTPGGHAEHEGSPYCHVPCYGYLFGPKGVNIGRVGCYIYENENAENERPSEH", "length": 213, "header": "tr|A0A8M9P9H3-1|A0A8M9P9H3_DANRE Isoform 1 of Cysteine-rich protein 3 OS=Danio rerio OX=7955 GN=crip3 PE=4 SV=1 CANONICAL=A0A8M9P9H3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P9H3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9H3/entry#A0A8M9P9H3-1", "sequence": { "sequence": "MTSICPRCDKTVFFAEKVSSLGKNWHRFCLKCERCSKILSPGGHAEHDGLPYCHKPCYGTLFGPKGVNIGGAGSYIYDTPPQTPVNKTCNSPSEGSPTTPWTTSQINFNQPKAATAPARMFAGETYLCPGCGKAVYFAEKVMSLGRNWHRPCLRCVRCKKTLTPGGHAEHEGSPYCHVPCYGYLFGPKGVNIGRVGCYIYENENAENERPSEH", "length": 213, "header": "tr|A0A8M9P9H3-1|A0A8M9P9H3_DANRE Isoform 1 of Cysteine-rich protein 3 OS=Danio rerio OX=7955 GN=crip3 PE=4 SV=1 CANONICAL=A0A8M9P9H3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:556515", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556515", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZNQ0-1", "protein_name": "Cysteine-rich protein 3", "gene_name": "Crip3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWTCPRCQQPVYFAEKVSSVGKHWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGCYLYNPPSPPPASSISLSPSNFSPPRPRTGLPRAKKSPPYLKTFTGETSLCPGCGDPVYFAEKVMSLGRNWHRPCLRCQRCRKTLTAGSHAEHDGMPYCHIPCYGYLFGPKGVNIGDVGCYIYDPVDIRPK", "length": 204 }, "evidence": [ { "id": "HGNC:17751", "url": "https://alliancegenome.org/gene/HGNC:17751#orthology", "database": "AGR" }, { "id": "RGD:1565018", "url": "https://alliancegenome.org/gene/RGD:1565018#orthology", "database": "AGR" }, { "id": "MGI:2152434", "url": "https://alliancegenome.org/gene/MGI:2152434#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-620", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-620#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6Q6R3-3", "protein_name": "Cysteine-rich protein 3", "gene_name": "Crip3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSWTCPRCQQPVYFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGCYLYNLPTPPPASRISLSPSNFSPPRPRTGLSRAKKGPPYLKTFTGETSLCPGCGDPVFFAEKVMSLGRNWHRPCLRCQRCRKTLTAGSHAEHDGMPYCHIPCYGYLFGPKGVNIGDVGCYIYDPVDIRSK", "length": 204 }, "evidence": [ { "id": "HGNC:17751", "url": "https://alliancegenome.org/gene/HGNC:17751#orthology", "database": "AGR" }, { "id": "RGD:1565018", "url": "https://alliancegenome.org/gene/RGD:1565018#orthology", "database": "AGR" }, { "id": "MGI:2152434", "url": "https://alliancegenome.org/gene/MGI:2152434#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-620", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-620#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6Q6R5-1", "protein_name": "Cysteine-rich protein 3", "gene_name": "CRIP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSWTCPRCQQPVFFAEKVSSLGKNWHRFCLKCERCHSILSPGGHAEHNGRPYCHKPCYGALFGPRGVNIGGVGSYLYNPPTPSPGCTTPLSPSSFSPPRPRTGLPQGKKSPPHMKTFTGETSLCPGCGEPVYFAEKVMSLGRNWHRPCLRCQRCHKTLTAGSHAEHDGVPYCHVPCYGYLFGPKGGQPHPRHWDGMYMPEVWHVHGLWVCVDNFPCG", "length": 217 }, "evidence": [ { "id": "HGNC:17751", "url": "https://alliancegenome.org/gene/HGNC:17751#orthology", "database": "AGR" }, { "id": "RGD:1565018", "url": "https://alliancegenome.org/gene/RGD:1565018#orthology", "database": "AGR" }, { "id": "MGI:2152434", "url": "https://alliancegenome.org/gene/MGI:2152434#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-620", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-620#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9H3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9H3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 86, "end_pos": 88, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P9H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9H3" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 64, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 86, "end_pos": 88 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P9K9-1", "uniprot_ac": "A0A8M9P9K9", "uniprot_id": "A0A8M9P9K9_DANRE", "mass": { "chemical_mass": 418845.0, "monoisotopic_mass": 418845.0 }, "refseq": { "ac": "XP_021327607", "name": "intermembrane lipid transfer protein VPS13C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327607" }, "gene_names": [ { "name": "vps13c", "type": "recommended", "evidence": [ { "id": "A0A8M9P9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9" } ] }, { "name": "vps13c", "type": "synonym", "evidence": [ { "id": "XP_021327607", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327607" } ] } ], "protein_names": [ { "name": "Intermembrane lipid transfer protein VPS13C isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#names_and_taxonomy" } ] }, { "name": "intermembrane lipid transfer protein VPS13C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021327607", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327607" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021327607.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021327607", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327607" } ] } ], "disease": [ { "disease_id": "DOID:0050753", "recommended_name": { "id": "DOID:0050753", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050753", "name": "cerebellar ataxia", "description": "A hereditary ataxia that is characterized by ataxia originating in the cerebellum." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050753", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050753" } ] }, { "disease_id": "DOID:0050766", "recommended_name": { "id": "DOID:0050766", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050766", "name": "choreaacanthocytosis", "description": "A neuroacanthocytosis characterized by progressive neurodegeneration and red cell acanthocytosis, with onset in the third to fifth decade of life and has_material_basis_in homozygous or compound heterozygous mutation in the VPS13A gene, which encodes chorein, on chromosome 9q21." }, "synonyms": [ { "id": "DOID:0050766", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050766", "name": "Levine-Critchley syndrome", "description": "" }, { "id": "DOID:0050766", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050766", "name": "choreo-acanthocytosis", "description": "" }, { "id": "MONDO:0008695", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008695", "name": "VPS13A-related neurodegenerative disease", "description": "A form of neuroacanthocytosis and is characterized clinically by a Huntington disease-like phenotype with progressive neurological symptoms including movement disorders, psychiatric manifestations and cognitive disturbances, and caused by a variation in the VPS13A gene." }, { "id": "MONDO:0008695", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008695", "name": "CHAC", "description": "" }, { "id": "MONDO:0008695", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008695", "name": "Chac", "description": "" }, { "id": "MONDO:0008695", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008695", "name": "Levine-Critchley syndrome", "description": "" }, { "id": "MONDO:0008695", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008695", "name": "VPS13A disease", "description": "" }, { "id": "MONDO:0008695", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008695", "name": "chorea-acanthocytosis", "description": "" }, { "id": "MONDO:0008695", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008695", "name": "choreoacanthocytosis", "description": "" }, { "id": "MIM:200150", "resource": "MIM", "url": "https://www.omim.org/entry/200150", "name": "Choreoacanthocytosis", "description": "Choreoacanthocytosis" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050766", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050766" } ] }, { "disease_id": "DOID:0060896", "recommended_name": { "id": "DOID:0060896", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060896", "name": "Parkinson's disease 23", "description": "An early-onset Parkinson disease that has_material_basis_in homozygous or compound heterozygous mutation in the VPS13C gene on chromosome 15q22." }, "synonyms": [ { "id": "DOID:0060896", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060896", "name": "autosomal recessive early-onset Parkinson's disease 23", "description": "" }, { "id": "DOID:0060896", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060896", "name": "autosomal recessive early-onset Parkinson disease 23", "description": "" }, { "id": "MONDO:0014796", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014796", "name": "autosomal recessive early-onset Parkinson disease 23", "description": "Any young-onset Parkinson disease in which the cause of the disease is a mutation in the VPS13C gene." }, { "id": "MONDO:0014796", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014796", "name": "PARK23", "description": "" }, { "id": "MONDO:0014796", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014796", "name": "Parkinson disease 23, autosomal recessive early-onset", "description": "" }, { "id": "MONDO:0014796", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014796", "name": "Parkinson disease 23, autosomal recessive, early onset", "description": "" }, { "id": "MONDO:0014796", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014796", "name": "VPS13C young-onset Parkinson disease", "description": "" }, { "id": "MONDO:0014796", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014796", "name": "autosomal recessive early-onset Parkinson disease 23", "description": "" }, { "id": "MONDO:0014796", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014796", "name": "autosomal recessive early-onset Parksinson disease type 23", "description": "" }, { "id": "MONDO:0014796", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014796", "name": "young-onset Parkinson disease caused by mutation in VPS13C", "description": "" }, { "id": "MIM:616840", "resource": "MIM", "url": "https://www.omim.org/entry/616840", "name": "Parkinson disease 23, autosomal recessive, early onset", "description": "Parkinson disease 23, autosomal recessive, early onset" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060896", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060896" } ] }, { "disease_id": "DOID:0111590", "recommended_name": { "id": "DOID:0111590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111590", "name": "Cohen syndrome", "description": "A syndrome characterized by facial dysmorphism, microcephaly, truncal obesity, impaired intellectual development, progressive retinopathy, and intermittent congenital neutropenia that has_material_basis_in homozygous or compound heterozygous mutation in the VPS13B gene on chromosome 8q22.2." }, "synonyms": [ { "id": "DOID:0111590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111590", "name": "COH1", "description": "" }, { "id": "DOID:0111590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111590", "name": "Hypotonia, obesity, and prominent incisors", "description": "" }, { "id": "DOID:0111590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111590", "name": "Pepper syndrome", "description": "" }, { "id": "MONDO:0008999", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008999", "name": "Cohen syndrome", "description": "Cohen syndrome (CS) is a rare genetic developmental disorder characterized by microcephaly, characteristic facial features, hypotonia, non-progressive intellectual deficit, myopia and retinal dystrophy, neutropenia and truncal obesity." }, { "id": "MONDO:0008999", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008999", "name": "Cohen syndrome", "description": "" }, { "id": "MONDO:0008999", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008999", "name": "cutis verticis gyrata, retinitis pigmentosa, and sensorineural deafness", "description": "" }, { "id": "MONDO:0008999", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008999", "name": "COH1", "description": "" }, { "id": "MONDO:0008999", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008999", "name": "Chs1", "description": "" }, { "id": "MIM:216550", "resource": "MIM", "url": "https://www.omim.org/entry/216550", "name": "Cohen syndrome", "description": "Cohen syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111590", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111590" } ] }, { "disease_id": "DOID:0111611", "recommended_name": { "id": "DOID:0111611", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111611", "name": "autosomal recessive spinocerebellar ataxia 4", "description": "An autosomal recessive cerebellar ataxia characterized by ataxic gait with spasticity, hyperreflexia of the lower limbs, and mitochondrial defects that has_material_basis_in homozygous or compound heterozygous mutation in the VPS13D gene on chromosome 1p36.22-p36.21." }, "synonyms": [ { "id": "DOID:0111611", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111611", "name": "SCA24", "description": "" }, { "id": "DOID:0111611", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111611", "name": "SCAR4", "description": "" }, { "id": "DOID:0111611", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111611", "name": "SCASI", "description": "" }, { "id": "DOID:0111611", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111611", "name": "spinocerebellar ataxia 24", "description": "" }, { "id": "DOID:0111611", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111611", "name": "spinocerebellar ataxia with saccadic intrusions", "description": "" }, { "id": "DOID:0111611", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111611", "name": "autosomal recessive cerebellar ataxia-saccadic intrusion syndrome", "description": "" }, { "id": "MONDO:0011811", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011811", "name": "autosomal recessive cerebellar ataxia-saccadic intrusion syndrome", "description": "Autosomal recessive cerebellar ataxia-saccadic intrusion syndrome is a rare hereditary ataxia characterized by a progressive cerebellar ataxia associated with disruption of visual fixation by saccadic intrusions (overshooting horizontal saccades with macrosaccadic oscillations and increased velocity of larger saccades). It presents with progressive gait, trunk and limb ataxia with pyramidal tract signs (increased tendon reflexes and Babinski sign), myoclonic jerks, fasciculations, cerebellar dysarthria, sensorimotor axonal neuropathy with impaired joint position, vibration, temperature, pain sensations, pes cavus, and saccadic intrusions with characteristic overshooting horizontal saccades, macrosaccadic oscillations, and increased velocity of larger saccades, without other eye movement disturbances." }, { "id": "MONDO:0011811", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011811", "name": "SCAR4", "description": "" }, { "id": "MONDO:0011811", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011811", "name": "SCASI", "description": "" }, { "id": "MONDO:0011811", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011811", "name": "spinocerebellar ataxia 24", "description": "" }, { "id": "MONDO:0011811", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011811", "name": "spinocerebellar ataxia 24 (formerly)", "description": "" }, { "id": "MONDO:0011811", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011811", "name": "spinocerebellar ataxia autosomal recessive 4", "description": "" }, { "id": "MONDO:0011811", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011811", "name": "spinocerebellar ataxia, autosomal recessive 4", "description": "" }, { "id": "MIM:607317", "resource": "MIM", "url": "https://www.omim.org/entry/607317", "name": "Spinocerebellar ataxia, autosomal recessive 4", "description": "Spinocerebellar ataxia, autosomal recessive 4" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111611", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111611" } ] }, { "disease_id": "DOID:14330", "recommended_name": { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions." }, "synonyms": [ { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "Parkinson disease", "description": "" }, { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "paralysis agitans", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "late-onset Parkinson disease", "description": "A Parkinson disease that begins after around the age of 50." }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "LOPD", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "PARK", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "PD", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, age of onset, modifier, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, late-onset", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, late-onset, susceptibility to, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, susceptibility to, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "autosomal dominant late-onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "hereditary late onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "hereditary late-onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "late-onset Parkinson disease", "description": "" }, { "id": "MIM:168600", "resource": "MIM", "url": "https://www.omim.org/entry/168600", "name": "Parkinson disease", "description": "Parkinson disease" } ], "unlinked_id_list": [], "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9K9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "vps13c", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070426-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070426-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "798746", "url": "https://www.ncbi.nlm.nih.gov/gene/798746", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026847", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026847", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026854", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026854", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:798746", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798746", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR16166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16166:SF125", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16166:SF125", 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}, { "id": "A0AC58G4L6", "url": "https://www.uniprot.org/uniprotkb/A0AC58G4L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G4L6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G4L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G4L7", "url": "https://www.uniprot.org/uniprotkb/A0AC58G4L7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G4L7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G4L7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G4L8", "url": "https://www.uniprot.org/uniprotkb/A0AC58G4L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G4L8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G4L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G4M5", "url": "https://www.uniprot.org/uniprotkb/A0AC58G4M5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G4M5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G4M5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G4N8", "url": "https://www.uniprot.org/uniprotkb/A0AC58G4N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G4N8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G4N8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070426-4", "url": "https://zfin.org/ZDB-GENE-070426-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3755, "header": "tr|A0A8M9P9K9-1|A0A8M9P9K9_DANRE Isoform 1 of Intermembrane lipid transfer protein VPS13C isoform X1 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=2 CANONICAL=A0A8M9P9K9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P9K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0A8M9P9K9-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3755, "header": "tr|A0A8M9P9K9-1|A0A8M9P9K9_DANRE Isoform 1 of Intermembrane lipid transfer protein VPS13C isoform X1 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=2 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P9L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0A8M9P9L4-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQPEEM", "length": 3627, "header": "tr|A0A8M9P9L4-1|A0A8M9P9L4_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X20 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=2 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PKS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0A8M9PKS2-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3751, "header": "tr|A0A8M9PKS2-1|A0A8M9PKS2_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X3 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=2 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PKS9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0A8M9PKS9-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQPEEM", "length": 3623, "header": "tr|A0A8M9PKS9-1|A0A8M9PKS9_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X21 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=2 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PPR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0A8M9PPR8-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3750, "header": "tr|A0A8M9PPR8-1|A0A8M9PPR8_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X4 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=2 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PPS2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0A8M9PPS2-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3739, "header": "tr|A0A8M9PPS2-1|A0A8M9PPS2_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X8 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=2 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q2F8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0A8M9Q2F8-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3743, "header": "tr|A0A8M9Q2F8-1|A0A8M9P9K9_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X1 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=2 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q2G3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0A8M9Q2G3-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARREKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3695, "header": "tr|A0A8M9Q2G3-1|A0A8M9P9K9_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X1 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=2 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q8M3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0A8M9Q8M3-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARREKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3711, "header": "tr|A0A8M9Q8M3-1|A0A8M9P9K9_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X1 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=2 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9QHR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0A8M9QHR8-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3754, "header": "tr|A0A8M9QHR8-1|A0A8M9P9K9_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X1 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=2 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4J9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4J9-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3734, "header": "tr|A0AC58G4J9-1|A0AC58G4J9_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X10 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4K2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4K2-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARREKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3710, "header": "tr|A0AC58G4K2-1|A0AC58G4K2_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X12 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4K4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4K4-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARREKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3702, "header": "tr|A0AC58G4K4-1|A0AC58G4K4_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X13 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4K5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4K5-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARREKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3698, "header": "tr|A0AC58G4K5-1|A0AC58G4K5_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X15 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4K8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4K8-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARREKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3699, "header": "tr|A0AC58G4K8-1|A0AC58G4K8_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X14 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4K9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4K9-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVYLSSVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3742, "header": "tr|A0AC58G4K9-1|A0AC58G4K9_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X7 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4L2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4L2-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQPEEM", "length": 3606, "header": "tr|A0AC58G4L2-1|A0AC58G4L2_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X23 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4L4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4L4-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARREKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3694, "header": "tr|A0AC58G4L4-1|A0AC58G4L4_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X17 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4L5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4L5-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARREKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3693, "header": "tr|A0AC58G4L5-1|A0AC58G4L5_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X18 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4L6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4L6-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRSNQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3738, "header": "tr|A0AC58G4L6-1|A0AC58G4L6_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X9 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4L7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4L7-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARREKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3690, "header": "tr|A0AC58G4L7-1|A0AC58G4L7_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X19 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4L8-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQPEEM", "length": 3618, "header": "tr|A0AC58G4L8-1|A0AC58G4L8_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X22 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4M5-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARRDSQAGEFVFNLESYVYKNPPRDKGRKVKKHKKPFRRSKKYEHKAEKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLDSFSYQYPSADEMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQRSEIKQLDGEIFREHYMYPGHRKTNIMITNRRVMCVKEIDVIGHFNKEWECQFESFQRPPCTEGGDLKIYYREHNKLNLIRKDGQAQVRVIHMKHPDMAERLREGIDNAQFARKQHQMARQKSQRFIKMGNS", "length": 3746, "header": "tr|A0AC58G4M5-1|A0AC58G4M5_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X5 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} }, { "isoform_ac": "A0AC58G4N8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9/entry#A0AC58G4N8-1", "sequence": { "sequence": "MVFESLVSDLLNRFIGDYVENLDKSQLKIGIWGGNVVLENLKVKENALSELDVPFKVKAGQIGKLTLKIPWKNLYNEAVVATLDGLYLLVVPGATIKYDAVKEERYLQEAKQKELQRIEETLQLVARREKPQEEKKDTFAEKLATQVIKNLQVKITSIHIRYEDDVSDPQKPLAMGLTLSELSLQTADENWKTCILNEAAKIIYKLGRLECFCAYWNVNGPIFYKDSWEGIVEKLKAGISTKNEELQGYQYIFKPIFASARMCINPNAEVELKSPKANLHLEVQNIAIEMTKSQYLSMVDLLESIDCMVKNGPYRKFRPDVPVHRNARQWWKYGISSILEVHVRRFNQMWNWTNIKKHRQTLKAYKAAYKVKLTQSAKVREDADKQIQELEKGLDVFNIVLARQQVQMEVVRSGQKLVAKKAATQKQSGGGFFSSFFGKKEGKKEEEDKEPESIDSIMTVEEKSKLYTAIGYSGSSHNLALPKHYVAVIVNFKLLSTSVTFREEPGVPEILKVQMIDLSTSISQRPGAQAIRVEAKLEHWYVTGLQQQGEVPSLIASLGDSDSSLLSVRFEINPEDSPADQLLRVHSQPVEIIYDALTVISITEFFKTGKGVDLEVITSATLSKLEEIKEKTATGLSHIIETRKVLDLRIDLKPSYLLLPKSGFYDGKSELMIVDFGYLQLNSVDQGGHQQVSASFSSLEEIMDRAYERYSLELRSVQILYSRSGEKWKSACHEGLSHQHILQPMDFTLQLAKCMVDKDARMPRFKVSGELPLLHLKISDQKIQGVLELVDSIPLPQTGSSPPSSPTGKKVLGMPLSNTRPKVLALDPTVLSYAVESESDEDTSEKSVDEESLRSTLEELTEVQFQFEVKAVLFELTRQAAQEDVVLAFSVSQLGAEGRIRTFDLSVTSYLKKISLDYCEGKDAQNQPLHLITSSDKHGSDLLKVEYIKADVNGPSFCTLFNNTEQTLKVEFSSLDFLLHTKALLSTINYMNSAIPQELTANKERETRRRADRAAAGKTVSKGSKDAGVVNFKLSAVLGSFRVAVCDDRSNIADIRVQGIDASVMVQAKETDVFARLRDIVVLDVDPKTIHKKAVSIVGEEVFSFKMTLYPGATEGDGYTDTSKVDGKVIMRLGCIQIVYLHKFLMSLLMFVDNFQTAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIRLKAPLIIIPQSSTSHNAFVVDLGLITVGNRFSLLAAEGFPLPAVLETMDIKLTQLKLSRTVLKHDADHLDIEILEPINLELLVKRNLAATWYNKIPGVEVNGVLMSMNMSLGQEDLGVLMRILAENIGEGSKAAAVEGTKASAKVEAVIDEGLMQTLPVGIGSLPALTNGAFTENVVNVLLNFEIKKVMLMLKKSKNGDESPFLVLDVSQLGIDTKVRKYDMEATTYIKTISMKCLEFPDSNGEPLCIISSSAESGADLLEVKYFKADRNGPNFASLYQNTEQKMNVVFSSLDLMLHTEALLSTMDFLSAALSTSSLPSPERESRKSEDMKTTSAKSTALSSPSDGDIIDLMVNMQLGAFNVLVCDQKSNMADIKIQGLDGSLQMKGTQTHMFTRLRDFIVINVDSKTIHKKAISIVGDEVFSFSMSLTPKATEGAGYTDTSKVDGKVKLNVGCIQVVYLHKFFMSLLNFSNNFQEAKEALSAATAQAAEKAASSVRDFAQKSFRLAMDIKLKAPLIIIPQSSTSHNAVEADLGLITVGNRFSLLPVEGRPLPAVIDNMDIQLTQLKLSRISMELDSDQTSSKLLEPVNLVLSVKRNLASSWYQKMAAIEVDGDLKPMKVALSQDDLSVLLRILMENIGEASDIQSDTALRQENVLVRARTATGSEILEEKLSESKLKETELLESVRFSFNVESLGLTLYNNDPSQPCVHEEKSCLGEFMLCKMKMSGKMLNNGNMEVSTILTTCTLDDRRSGIQRVTSRMLGRRDEETSEPMIDVTYSQSVDERSVVAVLQKLYLCASVEFLLAVADFFVQALPTSPPTQREKTNQLPLKYVSEPKIHTEPKAVPAQRTKLRAVVVDPEVVFVANLMKADAPALVASFQCDFSLLSEEAGQTMKANVRSLKVLACPFIRAEGDIAVTTVLRPCSVELETKMPANAPLAGSMTVEEVIVKISPIILNTVITITAAMAPKPKEELSQQKSGDQNSLWSLMSVANANYWFLGVDTASEVTESFTDVDSSKDGETFGLTVKVVQVTLESGLGHRTVPLLLAESSFSVTAQNWSSLLSVSADMTLEVNYFNETHAVWEPLLERVDNGKRRWNLKLDMKNNPVRDKSPVPGDDFIMLPDPRTAITICSKDTMNITVSKCCLNVFNNLAKAFSESTASTFDHSLKEKSPFTIRNALGVALIVQHSANLRVPGSSTLGKVHELAVDKSLDLEYSSFERSSRQSALQRQESCLFNLSIVPSGYSEISNIPLGKPGRRLYNVRQPMQEESVSVLLQIDASEGNKVITVRSPLQIKNHFSVPFAILKYSSELGGMVNVGVAEPEKECHVPLEAYRSQLFLLPVGPLENLYRASTTCIAWKEKVHVSSEVHAVLQCPATESNFLPLVVNTLAMPDDLSHIANHGEVEWDPAYLIHLHPPVTVKNLLPYSIRYLLEGSADIYELQEGSAADVLNSNVSGEIMELILIKYQGRNWTGRMRISRDMPEFITICFNCDTGEALTVDVCVHVSRVSGKFILSVHSPYWIINKTSRVLQYRAEDTFVKHPSDFRDVILFSFKKKNIFSKNKLQLCVSTSSWSEGFSLDTVGSYGCVRCPDKSGDYLVGVSIQMSSFNLTRIVTMSPFYTLVNKSLFELEVGEVQNNNGSSNKWHYISSTECLPFWPESSTEKLCVRVVGCESSSKSFFFNKQDSGTLLRMDQYGGVIVDVNISDHSTVISFTDYYDGAAPALVVNHTPSATVNFRQRGCEECWALRPGEAQRFAWDDPAGVRKLCWSCQDHIGELDLVKDECGQFAYSSLVQIHWVSFLDGRQRVLIFTEDVGIVTKARQAEELEQFQQEVNVSLQNLGLSLINNDIRQEIAYVGITSSGVVWEMRPKNRWKSFNHKNIGLLEKAYQNHINKSDPGWTMLETGIEVNFGRVPMLMRQPFSCQIRRNFLPGIHVELKQSPHQRSLRAQLYWLQVDNQLPGAIFPTVFHPVPLPKSIVQDSEPKPFIDVSIITRFNEHSQVMQFKYFMALVQEMAVKIDQGFLGAILALFTPATDSQDSKKKNKLIQKDLDALQAQLMESSLTDTSGLSFFEHFHISPIKLHLSLSLGSSGDESEQGDMVAIQSVNLLLKSIGATLTDVDDLIFKLAYFEVKYQFYRRDKLMWAVIRHYTEQFLTQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPIQGAVQGPEEFAEGLVIGVRSLLGHTVGGAAGMVSRITGSVGKGLAAITMDKEYQQKRREEMNRPTKDFGESLAKGGKGFLKGVVGGVTGIVTKPVEGAKKEGAAGFFKGIGKGLVGVVARPTGGIVDMASSTFQGIQRVAESTEEVTKLRPVRLIHEDGIIRPYDHHASEGYDLFQPEEM", "length": 3562, "header": "tr|A0AC58G4N8-1|A0AC58G4N8_DANRE Computationally mapped isoform of Intermembrane lipid transfer protein VPS13C isoform X24 OS=Danio rerio OX=7955 GN=vps13c PE=1 SV=1 CANONICAL=A0A8M9P9K9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:798746", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798746", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZMR7-1", "protein_name": "Vacuolar protein sorting 13 homolog C", "gene_name": "Vps13c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAEKEEKSLQDIKQKELCRIEEALQKAAEKGAHGEFMYGLESLLYKDVKPDKPKEAKKDTFLEKLATQVIKNVQVKITDIHIKYEDDVTDPERPLSFGVTLREFSLLTTNEHWTPCILNEAEKIIYKLVKLDSLSAYWNVGCCVSYRGSREHILDQLKCEILTSTNIPPDHQYIFQPISASAKLYMNPGAESEFKTPKLDGNVEVQNIAIELTKPQYLSMIDFLESLDYMVRNAPYRKYRPCLPLHTDCRQWWKYAIDSVLEVHIRRYTRPWSWNNIKNHRQLLKSYKMAYKNKLTQTKVSEEIQKQIQDLEKSLDVFNIILVRQQAQVEVIHSGQKLRKKSSEAGEKRGWFSGFWGKKECKKRDEESSVPETIDDLMTPEEKDKLFTAIGYSENAYNLALPKQYVAHILTLKLLSTSIVVRENRNVPEILRIQIIGLGTQVSQRPGAQALKIEAKLEHWYVTGLRQQDIVPSLVASIGDTTSSLLKIEFETNPENSPADQTLIVQSQPVEVIYDAKTINAVVEFFQSNKGLDLEQITSATLMKLEEIKARTATGLTHIIETRKVLDLRINLKPSYLIIPQTGFHHEKSNLLILDFGTFQLNSKDQGAQKTTNSSLEEIIDKAYDKFDVEIKSVQLLFAKAGENWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDVRMARFKVSGGLPLMHVRISDQKIRDALCLINSIPLPQKSSTQSPERQVASIPVLSGGTKVLLGTSLLLDGVESESDDEYFDAEDGDSQAARPVKASELRKAAEVPNEELVTLLLKFEIKEVVLELTKQQKEEETILVFNVTQLGTEATMRTFDLTAVSYLRKISLDYHEIKGSRKKPIHLVSSSDRPGLDLLKVEYIKVDRNGPSFQTTFEKTEQTVKVAFSSLNLLLQTQALLSSLNYLTTVIPSDSQNAGVAKEVQTITEKQKNSPLQKVMVPSRDSDVIGFRLFAKLNAFCVTVCDEKSNIAEIKIQGLDSSLSLQSKKQSLFARLENIIVTDVDPKTVHKKAVSIVGNEVFRFNLDLYPDATEGDSYTDMSTVDGVVALHVGCIQIVYLHKFLMSLLSFLNNFQVAKEALSAATAQAAEKAATSVKDLAQRSFRVSVDIDLKAPVIVIPQSSLSTNAVVVDLGLIRVHNQFSLVSGEDAVNPPVIDKMKVQLTKLKLCRTAIQSGVSHPDIQLLHPINLEFCVNRNLAANWYHKVPVVEIKGRLDSMNVSLNQEDLNLLFRILAENLGEATEDIDKGKPRIQEIGKTKACQDVSTPQDVHTTQGVPAARVEETRPVDIINVLLNFEIKEVVVTLMKKAEKKGNPLHELKILHLGMEAKVKAHDMTAKAYLRKITMRCFDFPDSKGEPLHIVNSSDVSDGTLLTMLFIKADSDGPDFQTIHDNTKQKLKVSFSSLDLVLHLEALLSLMDFLSCAVPSPDSSSSETESELKPLVGGSRSLAVKAVPSSSEGDVFDLKVTAELNAFNIFICDQKSNIAEIKIHGMDASVSMKAKQTDVFARLKNIIVMNVDSLSIHKKAVSILGDEVFRFQMSLYPDATEGENYGDMSKVDGRLGLKVGCIQIVYVHKFFMSLLSFLNNFQAAKEALSTATVQAAERAASSVKDLAQKSFRLLMDIDLKAPVITIPQSSVSPNVVIADLGLIRVENKFSLVSVEQLSLPPVADKMSVQLTQLKLSRTVLQADSPQHDIEILKPVNMLLSIQRNLSAAWYTQIPGMEITGKLKPMQVALSQDDLTVLMKILLENLGEASSQPSPTQFAQEAARVKRDTRSGPDCLKEQDLAEPKPPGDQTVTLQFDFHFDSLSIVLYNSDGCQESRLSFHNDSFRLGELTLHLMASAGKMFKDGSMNVSLKLKTCTLDDLREGIERATSRMIDKKNDQDGNSSMIDVSYSQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAMPESPENIAKDIQIPSRKTAPGRVKMEKDDSVKPNMTLKAMITDPEVVFVANLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACPFLRERRGKSVTTVLQPCSLFMEKCTWASGKQNINVMVKEFVIKISPIILNTVMTIMAALSPKTKEEDQEDTAEEKDSLWAIKPITDYNSWFLGVDMATEATESFRDFEHTQIEENCVVAVESVQVTLECGLGHRTVPLLLAESRFSGNIKNWTSLMAAAADMTLEVHYYNETHAVWEPLIERVEGKTPWSLKLNVKKNPLQDKSLMPGDDFIPEPHTAVHISSGSTMNITISKSCLNVFNNLAKGFSEGAASTFDYSLKDRAPFTVRNALGVPMKVQPNRNLRVMGSPEKSDVYDVGAGQHLELEYASLEPSRQGKLSLLSRQESTFFTLTFVPHGYTEVASVPVARPGRRLYNVRNPSASRSDSVLVQIDATEGNKVVTLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIVKPEEEFHVPLDSYRCQLYVQPAGSLEQQYTQSTTYISWKEELHRSREVRCMLQCPAVEVNFLPLIVNTVALPDELSYIGAHGEDWDPAYIIHLYPPLTLRNLLPYSIRYLLEGTAEAHELAEGSSADVLHSRISGEIIELVLVKYLGKNWNGHFRICDTLPEFFLVCFSSDTAEVLTVDLSVHVRRIGCRMELSVFSPYWLINKTSRVLQYRSEEIHVKHPADFRDIILFSFKKKNIFSKNKVQLKISTSAWSNGFSLDTVGSYGCVKCPATTMEYLVGVSIKMSSFNLSRIVTLTPFCTVANKSSLELEVGEIASDGSIPTNKWHYIASSECIPFWPENLSGKLCVRVVGYEGSSKPFFYNRQDNGTLLSLEDLNGGILVDINTAEHSTVITFSDYHEGSAPALIMNHTQWNVLTYKQSGSQEALVLLPGETRLFAWADPTGTRKLTWSYAANFGEHDLLKDECGQFPYDANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADLEVALSLHSLGLSLVNNENKQEVSYVGVTSSGVVWEMKPKQKWKPFSQKQIMLLEQSYQKHLTSQDRGWIKLDSNFEVNFDKVPMEMRLPLRCPIKRDFLSGIQVEFKQSPHQRSLRARLYWLQVDNQLPGTMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKVDQGFLGAVIALFTPTSDPEAERKRTKLIQQDIDALNTELLESSMSDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMIAIHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLMWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEMGRQPKDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIIDMASSTFQGIQRVAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLENQIKKLEGEAYQFHCTVPGNKRAVLMITNRRVLFIKEVEILGHMSVDWQCLFEDFLCPPGVSENLLKISVKEQGLFHKKDSANVGYLRKIYLKDPITAKRAFEAIESAQSARQQQRLMRQSSVKQ", "length": 3718 }, "evidence": [ { "id": "MGI:2444207", "url": "https://alliancegenome.org/gene/MGI:2444207#orthology", "database": "AGR" }, { "id": "HGNC:23594", "url": "https://alliancegenome.org/gene/HGNC:23594#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070426-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070426-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0033194", "url": "https://alliancegenome.org/gene/FB:FBgn0033194#orthology", "database": "AGR" }, { "id": "RGD:1560364", "url": "https://alliancegenome.org/gene/RGD:1560364#orthology", "database": "AGR" }, { "id": "SGD:S000003963", "url": "https://alliancegenome.org/gene/SGD:S000003963#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4A2-1", "protein_name": "Vacuolar protein sorting 13 homolog A", "gene_name": "Vps13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVFESVVVDVLNRFLGDYVVNLDQSQLSLGIWKGAVVLKNLVIKENALHELDVPFKVKVGRIGSLQLKIPWKNLYTQPVEAVLEEIYLLIVPSSRIQYDPIKEEKQLMEAKQQELKRIEEAKQKVVDQENPREEKQDTFAEKLVTQIIKNLQVQISSIHVRYEDDITNREKPLSFGISLQNLSLQTTDQYWIPCLHDDTEKLVRKLIRLDNLFAYWNVNSEMFYLNDYDDALEALKNGIVNENIIPEGYDFVFRPISANAKLQMNRRSDFDFSDPKINLDIELHTIVIEFNKPQYFSLMELLESIDMMTQNLPYRKFKPSVPLHLHAEEWWAYAIHGILEVNVCPSLRMWSWEHIKNHRYKMKQYREFYKKKLTNKKPSPEILMSLEELEKTLDVFNITIARQQAEVEVKKAGYKIYKEGLKDPEDNAGWFSWMWSWSESNANQQQDVKPGILAEMLTPEEKALLYEAIGYSETAVDPTLPKTFEALKFFVHLKSMSIVLRENRQKPELLNVVVEGLSTSIVQRPGAQALKFETKIDSFHITGLPDDFKKPHLLSSLDDMSLFRITFEINPLDETVSQRCTIEAEPLEMIYDARTVNSIVEFFRPPKDVRLAQLTTATLTKLEEFREKTATGLLYIIETQKVLDLRINVKASYVIVPQYGNFSPTSNLLLLDLGHLKVTSKRRSGLPDVKPSGASLEDIMHRAYDSFDIQLSSIQLLYSRVGDNWKEARKLNVSTQHILIPMHVNIELSKAMVFMDIKMPKFKIFGKLPLVSLRISDKKLQGIMELLESIPKPEPVTDVSAPARSFQIQASTMPVSHISQKLIPLLEQSATEDDSEEEFFDAPCSPLEEYPQVSCRVESTRRKKLQKKDGSMNFIQLSMRFEVAEVLIQFYHLVGDCELPVLEMGVLGLGTEVEIRKFDLKGNAFLKELWLKCPGYLDEHKKPVYLITTLDNTMEDLLTLEFMRVEKNAPNLNSTYNNVLQLIKVNFSSLDIHLHTEALLNTMNYLNNILPELGETSASVSAAEPEDKGDIIKKLALKLPTNEDIITLQLLAELSCLRIFIQDQKQNISEIKIEGLDSEMIMKPLVTEINAKLRNIIVLDSDKMAVYKKAVYITGKEVFSFKMISYMDATAGYAYTDMSVVDARVYLTVGCIEVVFVTKFLYSILAFINNFQAVKNALAEATVQAAGMAADGVKELARKSSRFALDVNIKAPVVLIPQSPVSRNVFVADFGLITIKNIFVTVTETQSNIPPVIDLITIKLSKMRLYRSQFMNNTYQEVLDLLLPLNLEVIVERNLSWEWYKEVPCFNIKAQLKPMEFILSQEDLTTVFQTLYGNIWYGRDVPAPSSVNKGPEIMTTEVTSTSYHSGATMVTSAVVEVHPQASPANTTLNVSFQTDHLIMTLYSPGPDQASFTDVRDPSLELAEFKLENIISDLKVYTDDSMVFSFSLKNCILDDKRPHVMKATPRMIGLTVGFDKKDMVDVKYRQIRDVFVTDVVVQEMYVCASVEFLMTVARVFFDAYMTSTALETSVQTWTTREAPVQELRKWEMNILIKNPEIVFVADMTRNDAPALVITTQCEICCKGEPESNTVTAAIKDFQVRACPFLPVKRKGRVTTVLQPCDLFYQATQFGTDPQTIDISVKSLTLKVSPVIINTIITVTSALYTTKETVPEESTSNVAHLWDKKDTKNLKMWFLEESNETEKVVPTDEVMPGGETLNLNIDSIFIVLEAGIGHRTVPMLLAKSSFLGESKNWRTLINLHCQLELEVHYFNEMFGVWEPLLEPLEIDQSDDFRPWNLGIKMKKKAKEAIVESDSEEENYKVPEYKTAISFFSRDQLNITLSKCGLVMLSNLVEAFTEAATGSSAVFLRDLAPFMILNSLGLTVSVSPSDSFHVLNVPLAKSYELKNEESLSMDYVRTKDNDHFNAMTSLSSKLFFILLTPANHSVADKIPLTKVGRRLYTVRHRESGVERSIICQIDTVEGSKKVTIRSPVQIKNHFSIPISVFEGDTLLGIASPENEFNIPLASYRSSLSLKPEDEDYQLCEGIDFEEIIKHDGQLLKKKCRSISPSKKSFVINIVPEKDNLASLSAYSEDGWDLPYVMHLWPPILIRNLLPYKIAYYLEGIENTVCTLSEGHSSQIYNVEMDQAKLHLKLLDYLNHDWKSEFQIDPNQQDINFINFTCLTEMEKSDLDIAIHMTYNTGQTVVAFHSPYWMVNKTNRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSDQFSIDTVGSHGAIKCKGLKMEYQVGVTIDLSSFNITRIVTFIPFYMIKNKSRYHISVTEEGSDKWLSLDLEQCIPFWPENASDILLIQVERSEGPPKRIYFNKQDSCILLRLDNELGGVIAEVNLAEHSTVITFSDYHEGAATFLLINHTKSDPVQYNQSSLSEIEDSLPPGKAVYYTWADPVGSRKLKWSCGQSYGEVTHKDDMMTPISVGKKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELAELEVVLALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKSRWKPMSVKHTEKLEKEFREYTESSPLEDKVVELDNSIPVLLTPSGNDMKILEPHVIAVRRNYLPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGAIFPFVFYPIKPPRSVTMDSAPKPFTDVSIVMRSAGHSQISRIKYFKVLIQEMDLRLDLGFVYALADLVPKTEVTEKTEVEYFHRDVEAFEQEFEVVSSVDQSQVNLFEYFHISPIKLHLSVSLSSGRDEAKDTEQHGGLIPVHSLNLLLKSIGATLTDVQDVVFKLAFFQLNYQFHTTSELQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITSAMAKGVAAMTMDEDYQQKRREAMNKQPAGLREGITRGGKGLVSGFVSGITGIVTKPIKGAQKEGAAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQMLQVMENGRFAKYKYFTHVMVNKTDMFMITRCGVLFVTKGTFGQLTCEWQYTFDEFTKEPFIVHGRRLRIEAKERVKSVFHAKEFGKIINFKTPEDARWILTKLEEAREPSPRL", "length": 3167 }, "evidence": [ { "id": "FB:FBgn0033194", "url": "https://alliancegenome.org/gene/FB:FBgn0033194#orthology", "database": "AGR" }, { "id": "SGD:S000003963", "url": "https://alliancegenome.org/gene/SGD:S000003963#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M2BET3-1", "protein_name": "Intermembrane lipid transfer protein VPS13A isoform X1", "gene_name": "vps13a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVFESVVVDVLNRFLGDYVGNLDSSQLSLGIWGGDAILRNLEIKENALSQLDIPFKVRAGHIGRLELKIPWKNLYTQSVEATLDEVYLLIVPTASIKYDAEKEERQLQESRQRELQRIEETKQKAAEKENPKGEKQDTFVEKLVTQVIKNLQVKISNIHVRYEDDVTNPSVPLSFGISLQNLSLQTADQNWNPCLLDEKAKLFFKLVRLDNLFAYWNVSSELYSNHNPEEALRYLKHSVAIQTAIPQDYHFIFRPISANAKLRMNPRSDVDFSSPKMDLVVNLPEVAVELSRPQYVSILELLGSVDMMTRNLPYRKYRPYVVVHTNARQWWRYVITGVLEVNVKPRLHMWSWLHIRRHRQHVKKYRELYKNKIISKKPAESLLKELEETERTLDIFNITMARQQAEMEASKAGLRIYRPGVKVEEEQSQGWFGWMWNWSGEASATQTKDVKTGGFDGLMTPAEKAKLYAAIGYSETAVNPNLPKNFENMKMNFHLLRLSLSIKESREKAEIIKLSVIDLKAMLTQRPAAQAIKISAQLSSFEVSGLPREKSAPILLSPRHVDGMKDKSLLNLMFETNPLDARADQRLRIESQPLEIIYDAMTVNSMSAFFMPPKDLQLDELTNATLMKLEQFRDKTSTGLMYIIETQKVLDLKINLMASYVIVPENGFYDPKHNLAILDLGHFQMSSQSRADLPQLSAGSSTLEDIMSRAYDSFDVQLSSLQFLYSKAGGDWKRARPLRQSAFHILEPVDLKVVFSRAMVVTDSRMPKFKMHGELPLLSLRISDDKVRGVLALLSSIPLPESRPTPQSRNTQATPKASKRGNTPQLTPRRPAIDDLRASIIYGSEEELFFDAPSSPIEDLPFFEASSDSRHASAADKRLSMVLKDPKKNMTEFLLSFEINKLSVQLCRVSNRQEVSVLHLFIDGLGTELKLRTFDMSSYTFLREICLECSEYLDSEDKKVHLITTLDNTEEDLLTLEYVKADKNAPDFKAMYKNTEQLIKVNFSSLDIHLHTEALLNSMNFLNNLLPPMKKETQEEQPIIPKEEEEEEEEEEEEEEAKVENSAVAKKSSYKKSKFEDVVNLHIRADLNCLKVFIRGEKARISEISIEGLVSEVQMKKKSVEILANLKNIIILDCDKEALYKKAVSIADKEVFDFRMVNHVDATEGDAYTDMHIVDTSVTLTVGCIQVIFLNKFMSSILAFINNFQEAKNALAEVTAQAAEKAATGVLELAERSTRISLDVDIKAPVVFLPQSSVSHNVIVADLGLVTVKNRFEIVSSPTHTKIPPVMDIMAVGLSDLKMYRTTFTDDKFNSEIQLLKPVNMDLSIKRNLSASWYHSIPDIQINAHLKPMSLILSQEDLTVVLKTLSENLSETSDAPPAPSSSDKGDTVSNKGSQGSGGNTVVTAAVVEGQKSGKLKNTLKLNFKFDSMTLVLYSPNSEIQLSDSRDESLKLAEFTLGTISTSVHMFSDSSMKASLKLTNCLLDDKRQGVKMITSRMMAMRQDREDSVMVDVSYRQSRDGTRLDTLVQDLYLCASMEFLLTVADVFLKALSDGFSGPPKSNKQPASTSKDPAAPAPPVVAKTEMNVVVKNPEIVFVADLTRAEAPALVMTTQCELVMKSEPSGQCMTAAISDLKIVACPFLREKRENNVTTVLQPCEVFFQSRQSNTEPQCIELSISALTLKVSPIIINTVITIQTALSPAAETPQELESPIPQDLWERRSLRDLKLWFLEEEGEEVSTSVTRLIPQGESLKMSIASICLTLEAGVGHRTVPMLLAKASFQGDVKDWSTLINLHCHLSMEVNYYNEMMGLWEPLLEPLDDEDKDGFRPWTLALKMKKKPVVSSGVSDEVDGAVPDYKTVISFTSKDQLNVTLSKCGLHMLSNLGTAFAEAAKQTAECFQTDQTPFVVKNRLGLAVSVLHSEVFRPIGKESKDRVVELPDGESLNLDYTLTAESSDQFSAMTSLSAKNYIQPTPVGHTTASVIPLIKTGRGMYSVMHNESRVTRFFVCQIYTVEGSKYVKIRSPFQIINHFSVPFRVYEGSVFLGESLPTEEFCVPLGSYRAELSLQPVPDGGEEYEHSESFTYTEVVQKPGKCLEKNCHLRGDSAQILKVNMVPLADTVTSHSSEEEFDKPIVLHLWPTVLLRNLLPYPITFKLKGIGDSPSVSLKEGHSSQIHTAIMDFSVLDLRLLGYLQQDWESQYSLSSEQDEISFIKFRSLAREEETESRPELDIAMHVKKEEGQVVLAVHSPYWMVNKTSRLLQYKADDIHRKHPKDYDMPLLFSFKPRNFLQNNKIRLMISESELSDDFSIDTVGSYGDVKCKGRQKDYLVGVKIDASSFSLTRLVTFLPFYMLVNRTKHVIRVCEEGQENWTEARPGQAAVPFWPERDSKKLRVKVEGSQSSPRAFDFHQPENCLLLHLDKSLGGIIVDVNLTEHSAVILFSDYHDGAAPFLLINHTKDETLQYHQSNSKRKPSTWFQDEILDLSMRDETDSLCSQAEIDELSPGQAVYYTWAEPTGSRILSWKLGKYKGELKSEEDQLLDVDKEGKLFLVSFYEGLQRVALFTSEQRIFKKICDSEKIELAQQEISILLQNMGISLVNNNSSQEVAFIGITSSDVVWETKPKKRSRWKVLSVKEAAVLEQHYRDYMENGPVDSTIIDLDNDYQVLFAANGVDMRIMQPYDAPLRRNFLPALKVEYSVSARQKTYRVQINRIQIQNQLQGAIFPFVFYPIKPPKSVSMDSEPKPLADVSIITRAAGHSDILRIKYFMVLIQEMDLRLDLGFLYAILELFTAEHTSAVTSEQEVELFDKDIEYLKTELNHVSATDTSPISLYEYFHISPIKLHLSLSLSSGGEDSNKQERETELIPVQSLHLLLKSIGATLTDAQDVLFKLGFFELRYQFRTTQQLQWEVVRHYSKQAIKQMYVLVLGLDVLGNPFGLIRGLSEGVEAFFYEPYQGAIQGPEEFMEGMALGVKALVGGAVGGLAGAASRITGAMAKGVAAMTMDEEYQQKRREAMNKQPSGLREGLTRGGKGLVSGFVSGITGIVTKPIKGAQKEGAAGFFKGMGKGLVGALTRPTGGIIDMASSTFQGIKRAAELSQDVESLRPPRFIHEDGVIRPYREREGLGSQMLQSIENGRFAKYRYFAHAKVNESDFLMITKRGIFFVTKGTFGQLTCEWQYLFDEFTKAPMIVEGRRLRIEAKERVKSVFHAKEFGKIINFKTPELAKWVLAKLEDARENLPK", "length": 3236 }, "evidence": [ { "id": "FB:FBgn0033194", "url": "https://alliancegenome.org/gene/FB:FBgn0033194#orthology", "database": "AGR" }, { "id": "SGD:S000003963", "url": "https://alliancegenome.org/gene/SGD:S000003963#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z713-1", "protein_name": "Intermembrane lipid transfer protein Vps13", "gene_name": "Vps13", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVFEAVVADVLNKVLGDYIENLDRNQLKIGIWGGDVVLQNLKIRENALDELDLPVQLIYGYLGKLVLKIPWKNLYSQPVIVNIEDLYVLVSPNNNVQYNAEKEAKYEMDLKKAALDALEAARKKELEMDQPKADAGFAEKLTAQIVNNLQVQITNVHLRYEDTTTTGSPFSFGISLHELELYTTDCDWEKCYMAQQASQVFKIANLSCLSAYLNCGGQLYANNKSDLSQQFKTNIACKETKPNYNYVLGPISCNAKLKLNMNPELDDPPFEKPKIDLTLEMEKLNVGLTNTQFDNLMKLGDAMNRQQLGIPYRKYRPYNIPYKGHARDWWHFAITSILEEEVRKPRESWTWGHIKTHRERCNTYAQKYKEQCLSKKPSAVLTETCRLLETELDVFNLLLIRQRVNIEIAKQREAVPEQKSGWFSGWGWGGGAKKDDQTTSQKLVEKFEAAMTSEEKEKMYRAIGYQENAKPTDLPESYEAIRMNFKLIALEVGLYKDERNSSAATKDFHELPSLVLLNFSMATALITQRPAAEAISIIAGMREIKVTGLTRNDYTPLLVESKITDEFNLLEVFFETNPLDKLCDQRVKVVARPLQITYDAPTILALINAFQTPGDVTLSKFEDAASTKISNFKERSATGMQYMIDKKAVLDVDILLMPNILVVPHKGVYDAGNVSLLVVSMGQVHLSSQPRRESNKLQHLFSAGEDKDEILKTVMENAYDRFTVAVDDVQMLVVRAGEPWQNALAEANSTEMHVLRPVSLKVTAALCVVDNDPRLPNIKVDIDLPAILVNVSEDRIFLAIKVATSIPLPEQKEPASRLTQTNSRSSMSISNFINKEVKKIGPSASGSSASKDPLLDEIIQYTSLDVNFSLGEINFVLFQSSRKCETSPDVSIEFLTPDGDVLPSQLTENIQEPIEELPPTPPQQILSIDIRRLEAHFVSKTYESVATVKLGDINLRQYDCQDSDMDVLDVIYTPKQENSSNYLFTVSCTIADKSSPEFSTKYNSTEQLVVANFEVLQIVLHQECLQRIMEVVNNFQRNLDLVLSSTRPRDRMGSIGGGDGIKRTLNVILEDTEEIMTTDQMKRRKKTRRTHVVETVKVRVIANLDQVGLVLTGRKRPIAEMNVKKFVSSLIIKSSYTEVNIGLKDIQVLDLNPYTIHKNILSIVGKDAFNCQIVIYNKEETQDYNSDDMKITVDIGCMKIIFLNWFVAGVMNFLNNFTAAQATISQAGAAAAESARQKAMDAYETATRMKLNIRIKAPIIIVPIGSQDRNALLLDLGLLELTNNTVEVAVAEEERLAVIDEIKLQICDVKISKIVLLDGNESTVDEVDAEVGFLSKFNMMNPMSCTLSITRNLSYTWYRDVPELNLSGRLKSIELTLFADDYALVMLVLNRNLNEGLEEFPPSEEAPQEAQVRPERRNSRAGRLSRTVQVSPIREKIHESIKFNFQFDGVVINLMEGEGAGLARFGIYFLSVKGTKLDNGTLSTSVVLCNIQMDDMRSNSKSQIRQYLSRKDWVQPKLDTDEIIDACYNERNFMVDVTAIIKEDDTFAEVRVRGFDLIVCIDFLLKLTTFLTLPPEENPRESVYIKPAPVSETARDTKHSIRSSAILAAQELVPVESSSHEVPNRKMNLILHIDEPDIILVENLEDLNTSCIIFNAQVHLNYRSINDKQIVNGQIDALKMYMCAFLPERREMTRHYILHPCVISLQGSTPEEEGMHISLKLSDIIINVSPATIELLNKAMLSVSSGTMTKCAIAEESRNYSNLWHQHHFHSRTYWFTKVEQGVDALEAEQRSVSTDNEKQKTEKCVIEIPSITLVIESGVGYYTKPLISLDTRITAVFNNWSRSLTAHGSLTLNMNYYNQALAEWEPIIELNEVIGRNGVREYTPWELKFEMGMEKVQSELEDDAEQQAMHMNIHSAETLEITLSKTCLGLLSELAEAFSQAIDQNGLTKPDIVAPYVLENDTGFDVNLNLRKGIFTLHEVHRGGTPVGANSTLLMVAQSEEVDPSVIKTCTISTGGRAYLQTKDLSTLSEEDSEDYTLYVTIGDINKEIALPVSKSDTRFFNLMRSTSHEPWGIISEVKQEYGTTKVNIHGVVSVHNHFTTGLNIYRRNPAPTAQCFEDIFVGRVRPGEVFHVPLHAIYAESKDLFFSMRGYRRSVQGISWASNPSDLNYSHQLHCDPTNTFEPLIMNARRSKSEVYFENTNKYTLLSAFYTIHLRPPLYLRNSLPINIQVSVAGCSVRKEDGLDAQSSQRFVDRGYRKEDFLDYGEKPVNSGDVLHLPTVRLASKGKESKSFLVVRLVQYLEKDWSCATEIWDYTDDVITWTFSSYDSEMKVDMDLYVKTENRHGSLMLTLFSPFWMINKTGMMLTYKSETTSVEVLYHPPEYSGPILFTFRDKLFFDKKKASIRIDNGQWSEKIPLDVAGSVGEVICFANNQKYPVGVHNHLTQNSLTKQITFIPFYIVCNKCHFDIELQEQSRPADPWLHLEPNEMEPLWPRNDTKNNLVVRVDGKITPAFDFTEVICTLLKLEDSKYGGINVDVQTTEGGVYITFTDYKPADAPGLLINHTGKQIVYHEKGTKNEHILNAKSTIMYAWDDPTGPKMLVFGTNKEETDLKRDGIGEVIMQDGGKVLWVSFLDGLQRVLLFTENESIANRTESTASLQSITQSIDLRIHGIGLSVINNETGLDILYLGVTSSGIIWESKKVTKNRFKELTINENALLEIEYQKYLVHKSVNDVQTYKLDNKFPIDFDLMILKKTVERNLRRSFYPAIWLSRKSSPFQSQLHVKINRIQVDNQFLDPIFPVVLAPIPPPKSVASTTSLKPFIECSMVQRIMPNSTVRQFKYARILIQEFLFKVDLNFLTAIAEMFAKEVSDEAAAKQFRQDVESIELPLSAFFEEHSLEEQKSFYDNLHLGPLKIHVSFSMAGSDTKALPGFLGSLVQGVGVTLTDVNDVVFRLAFFEREYQFFSQKQLINEITSHYTGQALKQLYVLVLGLDVLGNPYGLVVGLKKGVEDLFYEPFQGAIQGPGEFAEGLVLGVKSLFGHTVGGAAGAVSKITGAMGKGLAALTFDEDYQKKRRQGIQNKPKNFHEGLARSSKGLVMGFVDGVTGVVTKPVTGARDNGVEGFFKGLGKGAIGLVARPTAGVVDFASGSFEAVKRAADASEDVKRMRPPRFQHYDFVLRPYCLMEATGNKIMKETDKGKFATTDNFIHCEEIIQKSEYLVVTNYRVMYVQRNEMFGVWTSLWSYLWNEISSVAATARGVQFTVKTDGKKVLGLFSSKESPRKLVLVADERKRDALVDIIESQRSDPNPLRATIAYPAHN", "length": 3321 }, "evidence": [ { "id": "MGI:2444207", "url": "https://alliancegenome.org/gene/MGI:2444207#orthology", "database": "AGR" }, { "id": "HGNC:23594", "url": "https://alliancegenome.org/gene/HGNC:23594#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070426-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070426-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0033194", "url": "https://alliancegenome.org/gene/FB:FBgn0033194#orthology", "database": "AGR" }, { "id": "RGD:1560364", "url": "https://alliancegenome.org/gene/RGD:1560364#orthology", "database": "AGR" }, { "id": "SGD:S000003963", "url": "https://alliancegenome.org/gene/SGD:S000003963#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q07878-1", "protein_name": "Intermembrane lipid transfer protein VPS13", "gene_name": "VPS13", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLESLAANLLNRLLGSYVENFDPNQLNVGIWSGDVKLKNLKLRKDCLDSLNLPIDVKSGILGDLVLTVPWSSLKNKPVKIIIEDCYLLCSPRSEDHENDEEMIKRAFRLKMRKVSEWELTNQARILSTQSENKTSSSSSEKNNAGFMQSLTTKIIDNLQVTIKNIHLRYEDMDGIFTTGPSSVGLTLNELSAVSTDSNWAPSFIDITQNITHKLLTLNSLCLYWNTDSPPLISDDDQDRSLENFVRGFKDMIASKNSTAPKHQYILKPVSGLGKLSINKLGSTEEQPHIDLQMFYDEFGLELDDTEYNDILHVLSSIQLRQITKKFKKARPSFAVSENPTEWFKYIAACVINEIHEKNKMWTWESMKEKCEQRRLYTKLWVEKLKLKNLEAPLRDPIQEAQLSELHKDLTYDEIILFRSVAKRQYAQYKLGMTEDSPTPTASSNIEPQTSNKSATKNNGSWLSSWWNGKPTEEVDEDLIMTEEQRQELYDAIEFDENEDKGPVLQVPRERVELRVTSLLKKGSFTIRKKKQNLNLGSIIFENCKVDFAQRPDSFLSSFQLNKFSLEDGSPNALYKHIISVRNSSKDQSSIDNHATGEEEEEDEPLLRASFELNPLDGLADSNLNIKLLGMTVFYHVHFITEVHKFFKASNQHMETIGNIVNAAEATVEGWTTQTRMGIESLLEDHKTVNVSLDLQAPLIILPLDPHDWDTPCAIIDAGHMSILSDLVPKEKIKEIKELSPEEYDKIDGNEINRLMFDRFQILSQDTQIFVGPDIQSTIGKINTASSTNDFRILDKMKLELTVDLSILPKAYKLPTIRVFGHLPRLSLSINDIQYKTIMNLIANSIPSMIDDEENNGDYVNYSSGSEKEMKKQIQLQLKNTLKALENMQPLQIEQKFLELHFDIDQAKIAFFQCIKNDSRNSEKLVDILCQRLNFNFDKRAKEMNLDLRVHSLDVEDYIELTDNKEFKNLISSGVEKVTRSQKDLFTLKYKRVQRIVPHNDTLIELFDQDIVMHMSELQLVLTPRSVLTLMNYAMLTFTDPNAPEMPADVLRHNKEDRDDAPQKINMKIKMEAVNVIFNDDSIKLATLVLSAGEFTMVLLPERYNINLKLGGLELTDETNESFSRDSVFRKIIQMKGQELVELSYESFDPATNTKDYDSFLKYSTGSMHVNFIESAVNRMVNFFAKFQKSKVSFDRARLAAYNQAPSIDAVNNMKMDIVIKAPIIQFPKLVGTQENNYDTMRFYLGEFFIENKFSVIDESHKINHIKLGVREGQLSSNLNFDGSSQQLYLVENIGLLFNIDRDPLPQDDTPELKVTSNFESFALDLTENQLTYLLEISNKVSSAFNITDENSGESGGKGEIKSPSPDPASLSSESERTATPQSLQGSNKSNIKNPEQKYLDFSFKAPKIALTLYNKTKGVTSLNDCGLTRIMFQDIGCSLGLKNDGTVDGQAHVAAFRIEDVRNIKDNKHTELIPKSKNKEYQFVANISRKNLEVGRLLNISMTMDSPKMILAMDYLVSLKEFFDAIMSKSHENNLYYPENTNQKPENKAIVESVQEGGDVTKIQYSVNIIETALILLADPCDMNSEAISFKIGQFLVTDQNIMTVAANNVGIFLFKMNSSEEKLRLLDDFSSSLTIDKRNSTPQTLMTNIQLSVQPLLMRISLRDIRLAMLIFKRVTTLLNKMTEKEDNGEEEESTDKIQFSHEFERKLAVLDPSILGERSRASQSSDSESIEVPTAILKNETFNADLGGLRFILIGDVHEMPILDMNVNEITASAKDWSTDFEALASLETYVNIFNYSRSSWEPLLEMIPITFHLSKGHSEMDPAFSFDILTQRIAEITLSARSIAMLSHIPASLTEELPLASRVSQKPYQLVNDTELDFDVWIQDKTTEDNKNEVVLLKANTSLPWEFEDWRSIREKLDIDKSKNILGVCVSGQNYKTIMNIDATTEGENLHVLSPPRNNVHNRIVCEARCDENNVKIITFRSTLVIENTTSTEIELLVDSKDPNKPSLKYAIKPHQSKSVPVEYAYDSDIRIRPASEDIYDWSQQTLSWKSLLSNQMSIFCSSKEDSNQRFHFEIGAKYDEREPLAKIFPHMKIVVSASMTIENLLPADINFSIFDKREEKRTDFLKTGESMEVHHISLDSFLLMSVQPLQDEASASKPSIVNTPHKSPLNPEDSLSLTLSGGQNLLLKLDYKNIDGTRSKVIRIYSPYIIMNSTDRELYIQSSLLNIAQSKILLENEKRYTIPKMFSFDKEDDKSNRARIRFKESEWSSKLSFDAIGQSFDASVRIKNKEQESNLGINISEGKGKYLLSKVIEIAPRYIISNTLDIPIEVCETGSMDVQQIESNITKPLYRMRNIVDKQLVLKFLGGDSNWSQPFFIKNVGVTYLKVLKNSRHKLLKIEILLDKATIFIRIKDGGDRWPFSIRNFSDHDFIFYQRDPRKVSDPYKDDQSNESSSRSFKPIFYRIPSKSIMPYAWDFPTAKEKYLVLESGTRTREVRLAEIGELPPLRLDKRSKDKPAPIVGLHVVADDDMQALVIVNYKANVGLYKLKTASATTTSSVSVNSSVTDGFVQKDEDEKVNTQIVVSFKGVGISLINGRLQELLYINMRGIELRYNESKAYQTFSWKMKWMQIDNQLFSGNYSNILYPTEIPYTEKEIENHPVISGSISKVNDSLQAVPYFKHVTLLIQEFSIQLDEDMLYAMMDFIKFPGSPWIMDSRDYKYDEEIQLPDVSELKTAGDIYFEIFHIQPTVLHLSFIRSDEISPGLAEETEESFSSSLYYVHMFAMTLGNINEAPVKVNSLFMDNVRVPLPILMDHIERHYTTQFVYQIHKILGSADCFGNPVGLFNTISSGVWDLFYEPYQGYMMNDRPQEIGIHLAKGGLSFAKKTVFGLSDSMSKFTGSMAKGLSVTQDLEFQRVRRLQQRINKNNRNALANSAQSFASTLGSGLSGIALDPYKAMQKEGAAGFLKGLGKGIVGLPTKTAIGFLDLTSNLSQGVKSTTTVLDMQKGCRVRLPRYVDHDQIIKPYDLREAQGQYWLKTVNGGVFMNDEYLSHVILPGKELAVIVSMQHIAEVQMATQELMWSTGYPSIQGITLERSGLQIKLKSQSEYFIPISDPEERRSLYRNIAIAVREYNKYCEAIL", "length": 3144 }, "evidence": [ { "id": "MGI:2444207", "url": "https://alliancegenome.org/gene/MGI:2444207#orthology", "database": "AGR" }, { "id": "HGNC:23594", "url": "https://alliancegenome.org/gene/HGNC:23594#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070426-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070426-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0033194", "url": "https://alliancegenome.org/gene/FB:FBgn0033194#orthology", "database": "AGR" }, { "id": "RGD:1560364", "url": "https://alliancegenome.org/gene/RGD:1560364#orthology", "database": "AGR" }, { "id": "SGD:S000003963", "url": "https://alliancegenome.org/gene/SGD:S000003963#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5H8C4-1", "protein_name": "Intermembrane lipid transfer protein VPS13A", "gene_name": "Vps13a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVFESVVVEVLNRFLGDYVVNLDESQLSLGIWKGAVALKNLVIKENALHELDVPFKVKVGHIGSLKLKIPWKNLYTQPVEAVLEEIFLLIVPSSRIQYDPIKEEKQLMETKQQELKRIEKAKQKVFDKEKPREEKQDTFTEKLVTQIIQNLQVQISSIHIRYEDDITNGDKPLSFGISLQNISLQTTDQYWIPCLHDNTEKLVRKLIRLDNLFAYWNVNSEMFYLNDYDESLKALKNGIVNENIVPEGYDFVFRPISASAKLQMNRRSDFDFSDPKINLAVDLHTIAIEFNKPQYFSLMELLESIDMMTQNQPYRKFKPSVPLHLHAKEWWAYAIHSILEVNVCPSLRMWSWEHIRNHRYKMKRYREFYKKKLTSKKPSPEILMSLEELEKTLDVFNITIARQQAEVEAKKAGYKIYKEGVKDPEDNAGWFGWLWTWSESNANQQQDVKPGILEEMLTPEEKSLLYEAIGYSETAVDPTLPKTFEALKFFVHLKSMSIVLRENHQKPELLNVVVEGLSTSVVQRPGAQAIKFETKIDSFHITGLPDDFKKPHLLSSLDDTSLLQITFEINPLNETVAQRCTIEAEPLEIIYDARTVNSIVEFFRPPKDVHLAQLTSVTLTKLEEFRAKTATGLLYVIETQKVLDLRINVKASYVIVPQYGNFSPTSNLLLLDLGHLKVSSKRRSLLPDVRPSEASLEDIMHRAYDSFDIQLTSIQLLYSRVGDNWKEARKLNVSTQHILIPMHVNVELSKAMVFMDIKMPKFKISGKLPLVSLRISDKKLQGIMELLGSIPKPEPVTDVSAPARSFQIQASALPVSHISQKLIPLLEQPVTEDDSEEEFFDAPCSPLEECPQVSCRDKCTRQKKLQKKDCVMNLIQLRMRFEVAEVSIQFYHLVGDCELPVLEMGALGLGTEAEFRTFDLKGSAFLKELWLKCPEYLDENKKPVYLITTLDNTMEDLLTLEFMKVEKNAPNLNSTYNNVLQLIKVNFSSLDIHLHTEALLNTMNYLNNILPELREKSASVSAAEPEDKGDIIKKLALKLPTNEDIITLQLLAELSCLQIFIQDQKQNISEIKIEGLDSEMIMKPLVTEINAKLRNIIVLDSDKMAIYKKALYITGKEVFSFKMISYMDATAGYAYTDMSVVDIRVHLTVGCIEVVFITKFLYSILAFIDNFQAVKDALAEATVQAAEMAADGVKELARKSSRFALDVNIKAPVVLIPQSPVSQNVFVADFGLITMKNIFVTVTETQSNIPPVIDLITIKLSKMRLYRSQFRNDTYQEVLDLLLPLNLEVIVERNLSWEWYKEVPCFNIKAQLKPMEFILSQEDLTTVFQTLHGNIWYGQDLSAPSSANKDPETMTSGVTSPPDHSPATVVTAAVVEVHPQASQAHTMLNVSFQTDYLTMALYSPGPDEASFTDVRDPSLELAEFKLENIISSLKIYTDDSTVFSFSVKNCILDDKRSHVMKATPRMIGLTVGFDKKDMVDIKYRKIKTFVVTDAVVQEMYVCASVEFLMTVAHIFFDAYMTSTALETSVQTRTTREAPAQELGKWEMNILIKNPEIVFVADMTRNDAPALVITTQCEICCKGEPTSNTVTAAIKDLQVRACPFLPVKRKGKVTTVLQPCDLFYQATQLGRDPQMIDISVKSLTLKVSPVIINTIITITSALYTTKETVPEENTSNIAHLWDKKDTKNLKMWFLEESNESEKVVPTNEVMPGGETLNLRIDSIFIVLEAGIGHRTVPMLLAKACFSGESKNWLSLINLHCHLELEVHYYNEMFGVWEPLLEPLEIDQTDDFRPWNLGIKMKKKAKEAIVESDSEAENYKVPEYKTAISFYSRDQLNITLSKCGLVMLNNLVEAFTEAATGSSSVFLRDLAPFMIFNSLGLTVSVSPSDSFSVLNVPLAKSYELKNDESLSMDYVRTKDNDHFNAMTSLSSKLFFILLTPANHSVADKIPLTKVGRRLYTVRHRESGVERSIICQIDTVEGSKKVTIRSPVQIKNHFSIPISVFEGDTLLGIASPENEFNIPLASYRSSLSLVPEDQDYQLCEGIDFEEIIKYDGQLLKKKCRSTNPSKKSFVINIVPEKDNLASLSVYSEDGWDLPYVLHLWPPILIRNLLPYKVAYYIEGIENTVVTLSEGHSSQIYNVEMDQAKLHLKLLDYLNHDWKSEFYIRSSQQDINFINFTCLTEMEKSDLDIAIHMTYNTGQTVVAFHSPYWMVNKTNRMLQYKADGIHRKHPPNYTKPVLFSFQPNHFFNNNKVQLMVTDSELSDQFSIDTVGSHGAIRCKGLKMEYQVGVTINLSSFNITRIVTFIPFYMIKNKSKYHISVAEEGSDKWLSLDLEQSIPFWPENASNILLIQVERSEDPPKRIYFNKQDNCILLRLNNELGGIIAEVNLAEHSTVITFSDYHDGAATFLLINHTKSDPVQYNQSSLGEIEDSLPPGKAVYYTWADPVGSRKLKWSCGQSYGEVTHKDDMMTPISVGKKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELAELEVVLALQDVGISLVNNYTKQEVAYIGITSSDVVWEAKPKKKARWKPMSVKHTEKLEKEFREYTEASPLEDKVVELDNIPVRLTPSGNDMKILQPHVIPVRRNYLPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGAIFPFVFYPIKPPRSVTMDSAPKPFTDVSIVMRSAGHSQISRIKYFKVLIQEMDLSLDLGFVYALADLVTKAEVTEKTEVEHFHKDVEAFEQEYEVVSSVDQSQVNLFEYFHISPIKLHLSVSLSSGRDEAKDSEQHGGLIPVHSLNLLLKSIGATLTDVQDVVFKLAFFELNYQFHTTSELQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITSAMAKGVAAMTMDEDYQQKRREAMNKQPAGLREGITRGGKGLVSGFVSGITGIVTKPIKGAQKEGAAGFFKGVGKGLVGAVTRPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGSGNQMLQVMENGRFAKYKYFTHVMINKTDMFMITRRGVLFVTKGTFGQLTCEWQYTFDEFTKEPFIVHGRRLRIEAKERVKSVFHAKEFGKIVNFKTPEDARWILTKLEEAREPSPRL", "length": 3166 }, "evidence": [ { "id": "FB:FBgn0033194", "url": "https://alliancegenome.org/gene/FB:FBgn0033194#orthology", "database": "AGR" }, { "id": "SGD:S000003963", "url": "https://alliancegenome.org/gene/SGD:S000003963#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q709C8-1", "protein_name": "Intermembrane lipid transfer protein VPS13C", "gene_name": "VPS13C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAVKEEKSLQDVKQKELSRIEEALQKAAEKGTHSGEFIYGLENFVYKDIKPGRKRKKHKKHFKKPFKGLDRSKDKPKEAKKDTFVEKLATQVIKNVQVKITDIHIKYEDDVTDPKRPLSFGVTLGELSLLTANEHWTPCILNEADKIIYKLIRLDSLSAYWNVNCSMSYQRSREQILDQLKNEILTSGNIPPNYQYIFQPISASAKLYMNPYAESELKTPKLDCNIEIQNIAIELTKPQYLSMIDLLESVDYMVRNAPYRKYKPYLPLHTNGRRWWKYAIDSVLEVHIRRYTQMWSWSNIKKHRQLLKSYKIAYKNKLTQSKVSEEIQKEIQDLEKTLDVFNIILARQQAQVEVIRSGQKLRKKSADTGEKRGGWFSGLWGKKESKKKDEESLIPETIDDLMTPEEKDKLFTAIGYSESTHNLTLPKQYVAHIMTLKLVSTSVTIRENKNIPEILKIQIIGLGTQVSQRPGAQALKVEAKLEHWYITGLRQQDIVPSLVASIGDTTSSLLKIKFETNPEDSPADQTLIVQSQPVEVIYDAKTVNAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLVVPQTGFHHEKSDLLILDFGTFQLNSKDQGLQKTTNSSLEEIMDKAYDKFDVEIKNVQLLFARAEETWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDIRMARFKVSGGLPLMHVRISDQKMKDVLYLMNSIPLPQKSSAQSPERQVSSIPIISGGTKGLLGTSLLLDTVESESDDEYFDAEDGEPQTCKSMKGSELKKAAEVPNEELINLLLKFEIKEVILEFTKQQKEEDTILVFNVTQLGTEATMRTFDLTVVSYLKKISLDYHEIEGSKRKPLHLISSSDKPGLDLLKVEYIKADKNGPSFQTAFGKTEQTVKVAFSSLNLLLQTQALVASINYLTTIIPSDDQSISVAKEVQISTEKQQKNSTLPKAIVSSRDSDIIDFRLFAKLNAFCVIVCNEKNNIAEIKIQGLDSSLSLQSRKQSLFARLENIIVTDVDPKTVHKKAVSIMGNEVFRFNLDLYPDATEGDLYTDMSKVDGVLSLNVGCIQIVYLHKFLMSLLNFLNNFQTAKESLSAATAQAAERAATSVKDLAQRSFRVSINIDLKAPVIVIPQSSISTNAVVVDLGLIRVHNQFSLVSDEDYLNPPVIDRMDVQLTKLTLYRTVIQPGIYHPDIQLLHPINLEFLVNRNLAASWYHKVPVVEIKGHLDSMNVSLNQEDLNLLFRILTENLCEGTEDLDKVKPRVQETGEIKEPLEISISQDVHDSKNTLTTGVEEIRSVDIINMLLNFEIKEVVVTLMKKSEKKGRPLHELNVLQLGMEAKVKTYDMTAKAYLKKISMQCFDFTDSKGEPLHIINSSNVTDEPLLKMLLTKADSDGPEFKTIHDSTKQRLKVSFASLDLVLHLEALLSFMDFLSSAAPFSEPSSSEKESELKPLVGESRSIAVKAVSSNISQKDVFDLKITAELNAFNVFVCDQKCNIADIKIHGMDASISVKPKQTDVFARLKDIIVMNVDLQSIHKKAVSILGDEVFRFQLTLYPDATEGEAYADMSKVDGKLSFKVGCIQIVYVHKFFMSLLNFLNNFQTAKEALSTATVQAAERAASSMKDLAQKSFRLLMDINLKAPVIIIPQSSVSPNAVIADLGLIRVENKFSLVPMEHYSLPPVIDKMNIELTQLKLSRTILQASLPQNDIEILKPVNMLLSIQRNLAAAWYVQIPGMEIKGKLKPMQVALSEDDLTVLMKILLENLGEASSQPSPTQSVQETVRVRKVDVSSVPDHLKEQEDWTDSKLSMNQIVSLQFDFHFESLSIILYNNDINQESGVAFHNDSFQLGELRLHLMASSGKMFKDGSMNVSVKLKTCTLDDLREGIERATSRMIDRKNDQDNNSSMIDISYKQDKNGSQIDAVLDKLYVCASVEFLMTVADFFIKAVPQSPENVAKETQILPRQTATGKVKIEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACPFLREKRGKNITTVLQPCSLFMEKCTWASGKQNINIMVKEFIIKISPIILNTVLTIMAALSPKTKEDGSKDTSKEMENLWGIKSINDYNTWFLGVDTATEITESFKGIEHSLIEENCGVVVESIQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAVADVTLQVHYYNEIHAVWEPLIERVEGKRQWNLRLDVKKNPVQDKSLLPGDDFIPEPQMAIHISSGNTMNITISKSCLNVFNNLAKGFSEGTASTFDYSLKDRAPFTVKNAVGVPIKVKPNCNLRVMGFPEKSDIFDVDAGQNLELEYASMVPSSQGNLSILSRQESSFFTLTIVPHGYTEVANIPVARPGRRLYNVRNPNASHSDSVLVQIDATEGNKVITLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLFIQPAGILEHQYKESTTYISWKEELHRSREVRCMLQCPSVEVSFLPLIVNTVALPDELSYICTHGEDWDVAYIIHLYPSLTLRNLLPYSLRYLLEGTAETHELAEGSTADVLHSRISGEIMELVLVKYQGKNWNGHFRIRDTLPEFFPVCFSSDSTEVTTVDLSVHVRRIGSRMVLSVFSPYWLINKTTRVLQYRSEDIHVKHPADFRDIILFSFKKKNIFTKNKVQLKISTSAWSSSFSLDTVGSYGCVKCPANNMEYLVGVSIKMSSFNLSRIVTLTPFCTIANKSSLELEVGEIASDGSMPTNKWNYIASSECLPFWPESLSGKLCVRVVGCEGSSKPFFYNRQDNGTLLSLEDLNGGILVDVNTAEHSTVITFSDYHEGSAPALIMNHTPWDILTYKQSGSPEEMVLLPRQARLFAWADPTGTRKLTWTYAANVGEHDLLKDGCGQFPYDANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADYEITLSLHSLGLSLVNNESKQEVSYIGITSSGVVWEVKPKQKWKPFSQKQIILLEQSYQKHQISRDHGWIKLDNNFEVNFDKDPMEMRLPIRSPIKRDFLSGIQIEFKQSSHQRSLRARLYWLQVDNQLPGAMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKIDQGFLGAIIALFTPTTDPEAERRRTKLIQQDIDALNAELMETSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMFAVHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLIWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLFGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREELSRQPRDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIVDMASSTFQGIQRAAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLENHIKKLEGETYRYHCAIPGSKKTILMVTNRRVLCIKEVEILGLMCVDWQCPFEDFVFPPSVSENVLKISVKEQGLFHKKDSANQGCVRKVYLKDTATAERACNAIEDAQSTRQQQKLMKQSSVRLLRPQLPS", "length": 3753 }, "evidence": [ { "id": "MGI:2444207", "url": "https://alliancegenome.org/gene/MGI:2444207#orthology", "database": "AGR" }, { "id": "HGNC:23594", "url": "https://alliancegenome.org/gene/HGNC:23594#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070426-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070426-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0033194", "url": "https://alliancegenome.org/gene/FB:FBgn0033194#orthology", "database": "AGR" }, { "id": "RGD:1560364", "url": "https://alliancegenome.org/gene/RGD:1560364#orthology", "database": "AGR" }, { "id": "SGD:S000003963", "url": "https://alliancegenome.org/gene/SGD:S000003963#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BX70-1", "protein_name": "Intermembrane lipid transfer protein VPS13C", "gene_name": "Vps13c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLESVVADLLNRFLGDYVENLNKSQLKLGIWGGNVALDNLQIKENALSELDVPFKVKAGQIDKLTLKIPWKNLYGEAVVATLEGLYLLVVPGASIKYDAEKEEKSLQDIKQKELCRIEEALQKAAEKGAHSGEFMYGLENLLYKDVKPGRKRKKHKKHFKKRFKGLDRSKDKPKEAKKDTFLEKLATQVIKNVQVKITDIHIKYEDDITDPERPLSFGVTLREFSLLTTNEHWTPCILNEAEKIIYKLVKLDSLSAYWNVGCCMSYRGSREHILEQLKREILTSTNIPPDHQYIFQPISASAKLYMNPGAESELKTPKLDGNVEVQNIAIELTKPQYLSMIDFLESLDYMVRNAPYRKYKPCLPLHTNCRQWWKYAIDSVLEVHIRRYTQPWSWSNIKNHRQLLKSYKMAYKTKLTQAKVSEEIQKQIQDLEKSLDVFNIILVRQQAQVEVIHSGQKLRKKSAEAGEKRGWFSGFWGKKESKKRDEESSVPETIDDLMTPEEKDKLFTAIGYSENAYNLALPKQYVAHILTLKLVSTSIIIRENRNVPEILRVQIIGLGTQVSQRPGAQALKIEAKLEHWYVTGLRQQDIVPSLVASIGDTTSSLLKIEFETNPENSPADQTLIVQSQPVEVIYDAKTINAVVEFFQSNKGLDLEQITSATLMKLEEIKERTATGLTHIIETRKVLDLRINLKPSYLIIPQTGFHHEKSNLLILDFGTFQLNSKDQGAQKTANASLEEIIDKAYDKFDVEIRSVQLLFAKAEENWKKCRFQHPSTMHILQPMDIHVELAKAMVEKDVRMAKFKVSGGLPLMHVRISDQKIKDALCLINSIPLPQKSSTPSPERQVASIPVLSGGTKALLGTSLLLDGVESESDEEFFDAEDGDSQAARTVKASELKKAAEVPNEELVSLLLKFEIKEVVLELTKQQKEEETILVFNVTQLGTEATMRTFDLTAVSYLRKISLDYHDIKGSRKKPIHLISSSDRPGLDLLKVEYIKVDRNGPSFQTTFEKTEQTVKVAFSSLNLLLQTQALLSSLNYLTTVIPSDSQNTGVAKEVQAMPEKQKNSPLQKVMVPSRDSDVIGFRLFAKLNAFCVTVCDEKSNIAEIKIQGLDSSLSLQSKKQSLFARLENIIVTDVDPKTIHKKAVSIVGNEVFRFNLDLYPDATEGDSYTDMSTVDGVVALHVGCIQIVYLHKFLMSLLSFLNNFQVAKEALSAATAQAAEKAATSVKDLAQRSFRVSVDIDLKAPVIVIPQSSLSTNAVVVDLGLIRVHNRFSLVSGEDTANPPVIDKMEVQLTKLKLSRTAIQPGTSHPDIQLLHPINLEFFVSRNLAANWYHKVPVVEIKGRLDSMNVSLNQEDLNLLFRILAENLGEATEDLDKGKPRIQERGETKACREVSTPQDVHTTQGVPAARVEETRPVDIINVLLNFEIKEVVVTLMKKAERKGSPFHELKILHLGMEAKVKAHDMTAAAYLRNISMRCFHFPDSKGEPLRIVNTSDVSDGILLKLLFIKADSDGPDFKTIHDNTKQKLKVSFSSLDLVLHLEALLSLMDFLSSAIPSSDSSSSEKEPELKPLVGESRSLAIRAVPSSYEGDAFDLKITAELNAFNIFICDQKSNIAEIKIHGMDASISVKPKQTDVFARLKNIIVMNVDSLSIHKKAVSILGDEVFRFQMSLYPDATEGENYGDMSKVDGRLSLKVGCIQIVYVHKFFMSLLSFLNNFQAAKEALSTATVQAAERAASSVKDLAQKSFRLLMDIDLKAPVITIPQSSVSPNVVIADLGLIRVENKFSLVSVEQLALPPVADEMSIQLTQLKLARTVLQADSPQHDVEILKPVNMLLCIQRNLSAAWYTQIPGMEIKGELKPMQVALSQDDLTVLMKILLENLGEASSQPSPTQYAQEAARVKRDTRSGPDYLKEQELADPKPPGDQTVTLQFDFHFDSLSIILYNSDSSQEPRLSFHNDSFRLGELTLHLMASAGKMFKDGSMNVSLKLKTCTLDDLREGIERATSRMIDKKNDQDNNSSMIDISYSQDKNGSQVDAVLDKLYVCASVEFLMTVADFFIKAMPQSPENIAKEIQIPSRQTAAGRVKMEKDDSVRPNMTLKAMITDPEVVFVASLTKADAPALTASFQCNLSLSTSKLEQMMEASVRDLKVLACPFLRERRGKSITTVLQPCSLFMEKCTWASGKQNINIVVKEFVIKISPIILNTVMTIMAAMSPKTKEDEWKDTPKETDNLWAVKSITDYNSWFLGVDMATEVTENFRDSEHPSIEENCVVAVESVQVTLECGLGHRTVPLLLAESKFSGNIKNWTSLMAAAADMTLEVHYYNETHAVWEPLIERVEGNKPWSLKLNVKKNPIQDKSLMPGDDFIPEPQTAVHISSGATMNITISKSCLNVFSNLAKGFSEGAASTFDYSLKDRAPFTVKNALGVPMKVQPNRNLKVMGSPEKSDIYDVGAGQHLELDYASLEPSRQGKLSILSRQESSLFTLTFVPYGYTEVASVPVARPGRRLYNVRNPSASHSDSVLVQIDATEGNKVVTLRSPLQIKNHFSIAFIIYKFVKNVKLLERIGIARPEEEFHVPLDSYRCQLYVQPAGGLEQQYTHSSTYISWKEELHRSREVRCMLQCPAVEVSFLPLIVNTVALPDELSYIGAHGEDWDPAYVIHLYPPLTLRNLLPYSLRYLLEGTAETHELAEGSSADVLHSRISGEIIELVLVKYLGKNWNGHFRICDTLPEFFLVCFSSDTAEVMTVDLSVHVRRIGCRMELSVFSPYWLINKTSRVLQYRSEEIHVKHPADFRDIILFSFKKKNIFSKNKVQLKISTSAWSNGFSLDTVGSYGCVKCPATNMEYLVGVSIKMSSFNLSRVVTLTPFCTVANKSSLDLEVGEIASDGSIPTNKWHYVASSECIPFWPENLSGKLCVRVVGYEGSSKPFFYNRQDNGTLLSLEDLNGGILVDINTAEHSTVITFSDYHEGSAPALIMNHTQWDVLTYKQSGSQEELVLLPGETRLFAWADPTGIRKLTWNYAANFGEHDLLKDECGQFPYDANIQIHWVSFLDGRQRVLLFTDDVALVSKALQAEEMEQADHEVALSLHSLGLSLVNNENKQEVSYVGITSSGVVWEMKPKQKWKPFSQKQIMSLEQAYSKRLASQDRGWVKLDSNFEVNFDKVPMEMRLPIRCPIKRDFLSGIQVEFKQSPHQRSLRARLYWLQVDNQLPGTMFPVVFHPVAPPKSIALDSEPKPFIDVSVITRFNEYSKVLQFKYFMVLIQEMALKVDQGFLGAVISLFTPTTDPEAERKRTKLIQQDIDALNTELMESSMTDMSILSFFEHFHISPVKLHLSLSLGSGGEESDKEKQEMIAIHSVNLLLKSIGATLTDVDDLIFKLAYYEIRYQFYKRDQLMWSVVRHYSEQFLKQMYVLVLGLDVLGNPFGLIRGLSEGVEALFYEPFQGAVQGPEEFAEGLVIGVRSLVGHTVGGAAGVVSRITGSVGKGLAAITMDKEYQQKRREEMGRQPKDFGDSLARGGKGFLRGVVGGVTGIITKPVEGAKKEGAAGFFKGIGKGLVGAVARPTGGIIDMASSTFQGIQRVAESTEEVSSLRPPRLIHEDGIIRPYDRQESEGSDLLENHIKKLEGEAYQFHCAVPGNKRAVLMITNRRALFIKEVEILGHMSVDWQCLFEDFVCPPEVSENLLKISVKEQGLFHKKDSANIGHLRKIYLKDPITAKRAFDAIESAQSARQQQKLMRQSSVKLLRPQGPS", "length": 3748 }, "evidence": [ { "id": "MGI:2444207", "url": "https://alliancegenome.org/gene/MGI:2444207#orthology", "database": "AGR" }, { "id": "HGNC:23594", "url": "https://alliancegenome.org/gene/HGNC:23594#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070426-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070426-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0033194", "url": "https://alliancegenome.org/gene/FB:FBgn0033194#orthology", "database": "AGR" }, { "id": "RGD:1560364", "url": "https://alliancegenome.org/gene/RGD:1560364#orthology", "database": "AGR" }, { "id": "SGD:S000003963", "url": "https://alliancegenome.org/gene/SGD:S000003963#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96RL7-1", "protein_name": "Intermembrane lipid transfer protein VPS13A", "gene_name": "VPS13A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVFESVVVDVLNRFLGDYVVDLDTSQLSLGIWKGAVALKNLQIKENALSQLDVPFKVKVGHIGNLKLIIPWKNLYTQPVEAVLEEIYLLIVPSSRIKYDPLKEEKQLMEAKQQELKRIEEAKQKVVDQEQHLPEKQDTFAEKLVTQIIKNLQVKISSIHIRYEDDITNRDKPLSFGISLQNLSMQTTDQYWVPCLHDETEKLVRKLIRLDNLFAYWNVKSQMFYLSDYDNSLDDLKNGIVNENIVPEGYDFVFRPISANAKLVMNRRSDFDFSAPKINLEIELHNIAIEFNKPQYFSIMELLESVDMMAQNLPYRKFKPDVPLHHHAREWWAYAIHGVLEVNVCPRLWMWSWKHIRKHRQKVKQYKELYKKKLTSKKPPGELLVSLEELEKTLDVFNITIARQTAEVEVKKAGYKIYKEGVKDPEDNKGWFSWLWSWSEQNTNEQQPDVQPETLEEMLTPEEKALLYEAIGYSETAVDPTLLKTFEALKFFVHLKSMSIVLRENHQKPELVDIVIEEFSTLIVQRPGAQAIKFETKIDSFHITGLPDNSEKPRLLSSLDDAMSLFQITFEINPLDETVSQRCIIEAEPLEIIYDARTVNSIVEFFRPPKEVHLAQLTAATLTKLEEFRSKTATGLLYIIETQKVLDLKINLKASYIIVPQDGIFSPTSNLLLLDLGHLKVTSKSRSELPDVKQGEANLKEIMDRAYDSFDIQLTSVQLLYSRVGDNWREARKLSVSTQHILVPMHFNLELSKAMVFMDVRMPKFKIYGKLPLISLRISDKKLQGIMELIESIPKPEPVTEVSAPVKSFQIQTSTSLGTSQISQKIIPLLELPSVSEDDSEEEFFDAPCSPLEEPLQFPTGVKSIRTRKLQKQDCSVNMTTFKIRFEVPKVLIEFYHLVGDCELSVVEILVLGLGAEIEIRTYDLKANAFLKEFCLKCPEYLDENKKPVYLVTTLDNTMEDLLTLEYVKAEKNVPDLKSTYNNVLQLIKVNFSSLDIHLHTEALLNTINYLHNILPQSEEKSAPVSTTETEDKGDVIKKLALKLSTNEDIITLQILAELSCLQIFIQDQKCNISEIKIEGLDSEMIMRPSETEINAKLRNIIVLDSDITAIYKKAVYITGKEVFSFKMVSYMDATAGSAYTDMNVVDIQVNLIVGCIEVVFVTKFLYSILAFIDNFQAAKQALAEATVQAAGMAATGVKELAQRSSRMALDINIKAPVVVIPQSPVSENVFVADFGLITMTNTFHMITESQSSPPPVIDLITIKLSEMRLYRSRFINDAYQEVLDLLLPLNLEVVVERNLCWEWYQEVPCFNVNAQLKPMEFILSQEDITTIFKTLHGNIWYEKDGSASPAVTKDQYSATSGVTTNASHHSGGATVVTAAVVEVHSRALLVKTTLNISFKTDDLTMVLYSPGPKQASFTDVRDPSLKLAEFKLENIISTLKMYTDGSTFSSFSLKNCILDDKRPHVKKATPRMIGLTVGFDKKDMMDIKYRKVRDGCVTDAVFQEMYICASVEFLQTVANVFLEAYTTGTAVETSVQTWTAKEEVPTQESVKWEINVIIKNPEIVFVADMTKNDAPALVITTQCEICYKGNLENSTMTAAIKDLQVRACPFLPVKRKGKITTVLQPCDLFYQTTQKGTDPQVIDMSVKSLTLKVSPVIINTMITITSALYTTKETIPEETASSTAHLWEKKDTKTLKMWFLEESNETEKIAPTTELVPKGEMIKMNIDSIFIVLEAGIGHRTVPMLLAKSRFSGEGKNWSSLINLHCQLELEVHYYNEMFGVWEPLLEPLEIDQTEDFRPWNLGIKMKKKAKMAIVESDPEEENYKVPEYKTVISFHSKDQLNITLSKCGLVMLNNLVKAFTEAATGSSADFVKDLAPFMILNSLGLTISVSPSDSFSVLNIPMAKSYVLKNGESLSMDYIRTKDNDHFNAMTSLSSKLFFILLTPVNHSTADKIPLTKVGRRLYTVRHRESGVERSIVCQIDTVEGSKKVTIRSPVQIRNHFSVPLSVYEGDTLLGTASPENEFNIPLGSYRSFIFLKPEDENYQMCEGIDFEEIIKNDGALLKKKCRSKNPSKESFLINIVPEKDNLTSLSVYSEDGWDLPYIMHLWPPILLRNLLPYKIAYYIEGIENSVFTLSEGHSAQICTAQLGKARLHLKLLDYLNHDWKSEYHIKPNQQDISFVSFTCVTEMEKTDLDIAVHMTYNTGQTVVAFHSPYWMVNKTGRMLQYKADGIHRKHPPNYKKPVLFSFQPNHFFNNNKVQLMVTDSELSNQFSIDTVGSHGAVKCKGLKMDYQVGVTIDLSSFNITRIVTFTPFYMIKNKSKYHISVAEEGNDKWLSLDLEQCIPFWPEYASSKLLIQVERSEDPPKRIYFNKQENCILLRLDNELGGIIAEVNLAEHSTVITFLDYHDGAATFLLINHTKNELVQYNQSSLSEIEDSLPPGKAVFYTWADPVGSRRLKWRCRKSHGEVTQKDDMMMPIDLGEKTIYLVSFFEGLQRIILFTEDPRVFKVTYESEKAELAEQEIAVALQDVGISLVNNYTKQEVAYIGITSSDVVWETKPKKKARWKPMSVKHTEKLEREFKEYTESSPSEDKVIQLDTNVPVRLTPTGHNMKILQPHVIALRRNYLPALKVEYNTSAHQSSFRIQIYRIQIQNQIHGAVFPFVFYPVKPPKSVTMDSAPKPFTDVSIVMRSAGHSQISRIKYFKVLIQEMDLRLDLGFIYALTDLMTEAEVTENTEVELFHKDIEAFKEEYKTASLVDQSQVSLYEYFHISPIKLHLSVSLSSGREEAKDSKQNGGLIPVHSLNLLLKSIGATLTDVQDVVFKLAFFELNYQFHTTSDLQSEVIRHYSKQAIKQMYVLILGLDVLGNPFGLIREFSEGVEAFFYEPYQGAIQGPEEFVEGMALGLKALVGGAVGGLAGAASKITGAMAKGVAAMTMDEDYQQKRREAMNKQPAGFREGITRGGKGLVSGFVSGITGIVTKPIKGAQKGGAAGFFKGVGKGLVGAVARPTGGIIDMASSTFQGIKRATETSEVESLRPPRFFNEDGVIRPYRLRDGTGNQMLQVMENGRFAKYKYFTHVMINKTDMLMITRRGVLFVTKGTFGQLTCEWQYSFDEFTKEPFIVHGRRLRIEAKERVKSVFHAREFGKIINFKTPEDARWILTKLQEAREPSPSL", "length": 3174 }, "evidence": [ { "id": "FB:FBgn0033194", "url": "https://alliancegenome.org/gene/FB:FBgn0033194#orthology", "database": "AGR" }, { "id": "SGD:S000003963", "url": "https://alliancegenome.org/gene/SGD:S000003963#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "protein retention in Golgi apparatus", "id": "GO:0045053", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045053", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9K9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9" } ], "pmid": "" }, { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9K9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9" } ], "pmid": "" }, { "name": "mitochondrion organization", "id": "GO:0007005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007005", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9K9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9" } ], "pmid": "" }, { "name": "protein targeting to vacuole", "id": "GO:0006623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006623", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9K9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1006, "end_pos": 1008, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1356, "end_pos": 1358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1717, "end_pos": 1719, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2311, "end_pos": 2313, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2330, "end_pos": 2332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2391, "end_pos": 2393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2490, "end_pos": 2492, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2707, "end_pos": 2709, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2724, "end_pos": 2726, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2778, "end_pos": 2780, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2863, "end_pos": 2865, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2878, "end_pos": 2880, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2893, "end_pos": 2895, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2957, "end_pos": 2959, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2981, "end_pos": 2983, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3088, "end_pos": 3090, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3147, "end_pos": 3149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 395, "end_pos": 397, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9" }, { "id": "PF12624", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12624" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Chorein N-terminal", "eco_id": "ECO_0000259", "start_pos": 2, "end_pos": 841, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9" }, { "id": "PF25037", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Intermembrane lipid transfer protein VPS13-like C-terminal", "eco_id": "ECO_0000259", "start_pos": 3596, "end_pos": 3715, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9" }, { "id": "PF25033", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25033" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VPS13-like middle region", "eco_id": "ECO_0000259", "start_pos": 1089, "end_pos": 1385, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P9K9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9K9" }, { "id": "PF25036", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25036" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Vacuolar protein sorting-associated protein 13 VPS13 adaptor binding", "eco_id": "ECO_0000259", "start_pos": 2481, "end_pos": 3016, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1006, "end_pos": 1008 }, { "start_pos": 1356, "end_pos": 1358 }, { "start_pos": 1717, "end_pos": 1719 }, { "start_pos": 2311, "end_pos": 2313 }, { "start_pos": 2330, "end_pos": 2332 }, { "start_pos": 2391, "end_pos": 2393 }, { "start_pos": 2490, "end_pos": 2492 }, { "start_pos": 2707, "end_pos": 2709 }, { "start_pos": 2724, "end_pos": 2726 }, { "start_pos": 2778, "end_pos": 2780 }, { "start_pos": 2863, "end_pos": 2865 }, { "start_pos": 2878, "end_pos": 2880 }, { "start_pos": 2893, "end_pos": 2895 }, { "start_pos": 2957, "end_pos": 2959 }, { "start_pos": 2981, "end_pos": 2983 }, { "start_pos": 3088, "end_pos": 3090 }, { "start_pos": 3147, "end_pos": 3149 }, { "start_pos": 395, "end_pos": 397 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P9M8-1", "uniprot_ac": "A0A8M9P9M8", "uniprot_id": "A0A8M9P9M8_DANRE", "mass": { "chemical_mass": 104075.0, "monoisotopic_mass": 104075.0 }, "refseq": { "ac": "XP_021323148", "name": "neutral alpha-glucosidase C isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323148" }, "gene_names": [ { "name": "ganc", "type": "recommended", "evidence": [ { "id": "A0A8M9P9M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8" } ] }, { "name": "ganc", "type": "synonym", "evidence": [ { "id": "XP_021323148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323148" } ] } ], "protein_names": [ { "name": "Neutral alpha-glucosidase C isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P9M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8/entry#names_and_taxonomy" } ] }, { "name": "neutral alpha-glucosidase C isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323148" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323148" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ganc", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-754", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-754", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P9M8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P9M8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000074556", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000074556", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06603", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06603", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14752", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14752", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100536353", "url": "https://www.ncbi.nlm.nih.gov/gene/100536353", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011013", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011013", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030458", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030458", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048395", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048395", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100536353", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536353", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHNVYGH", "url": "https://omabrowser.org/oma/group/MHNVYGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P9M8", "url": "https://www.orthodb.org/?gene=A0A8M9P9M8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F6D4", "url": "https://www.orthodb.org/?gene=E7F6D4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22762", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22762", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22762:SF60", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22762:SF60", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01055", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01055", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13802", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13802", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21365", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323148", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P9M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPE4", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPE4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPE4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPE9", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPE9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPF8", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPF8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPG1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPG1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPG2", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPG2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPH1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPH1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPK4", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPK4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F6D4", "url": "https://www.uniprot.org/uniprotkb/E7F6D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F6D4-1", "url": "https://www.uniprot.org/uniprotkb/E7F6D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-754", "url": "https://zfin.org/ZDB-GENE-130530-754", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEVNVSTESIESVLKSEDKFRKNHEILFYRRQRDKAVSQYFTSYETFVLTDGGASLELCERDSQDRLSLQIRATQNGTIRVSIDELQLVKPRYQVSDVLVGELRYEPLRVEWKKEDCVCLTWGLGQYQLLAFFSPFKLEISCAGEEIVTLNPGNKLCFETLQDPASRSSSNSSEGDENCCGLWKETFRQFEDIKANGPSSVGLDLSLHGFNHTYGVPEHADTLLLKDTSVSEAYRLYNLDVFGYEINSRLGLYGSVPLLLAHKPERTAGVFWLNSSETLVDVKYNTEQNEDEDEPPGKKSRISPRTDVRWISESGTIDCFILLGPTPAQVFSQYAQLTGKCRCRLYNGCARNRPLLSYQALPPLFSLGNHQCRWNYEDEADVKAVDAGFDLHGIPYDVIWLDIEHTDGKRYFTWDSKRFPNPAELQHHLMKKKRKLVVISDPHIKMDPDWSIYCEAKKGGHFVKNREGFDFEGTCWPGESCYLDFSSSKTRLWYARQFSLSKYEGSTESLFVWNDMNEPSVFNGPEQTMPKDALHHGGWEHRELHNLYGFYQHMATFEGLLTRSGGTERPFILTRSFFAGSQRLGAIWTGDNVATWEYLKISIPMLLSLSLTGIQFCGADVGGFVQDPDPELLVRWYQAGALQPFFRAHSAKMTKRREPWLFGEEVTSAIRSAVQDRYCLLPYWYTLFHQAHTAALPPIRPLWVEFPKDTSTFAVENQYMIGGALLVCPVTDPGVTEVKVLLPGSNELWYDTNTSEVHKGARSLDVPVTLTTVLVFQRGGTVVPRRTACGSCTADLQHYTITLTVALDIKGKADGFLYLDDGHSFNYRDQMQFCLRRFSMQAGRLVNSCANDKGLFVSDDKVETVVILGLKSVKRKPKLKSGAKRTSVMFEFDKKRGVLTLSGLELEICKDWEIII", "length": 916, "header": "tr|A0A8M9P9M8-1|A0A8M9P9M8_DANRE Isoform 1 of Neutral alpha-glucosidase C isoform X1 OS=Danio rerio OX=7955 GN=ganc PE=3 SV=1 CANONICAL=A0A8M9P9M8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P9M8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8/entry#A0A8M9P9M8-1", "sequence": { "sequence": "MEVNVSTESIESVLKSEDKFRKNHEILFYRRQRDKAVSQYFTSYETFVLTDGGASLELCERDSQDRLSLQIRATQNGTIRVSIDELQLVKPRYQVSDVLVGELRYEPLRVEWKKEDCVCLTWGLGQYQLLAFFSPFKLEISCAGEEIVTLNPGNKLCFETLQDPASRSSSNSSEGDENCCGLWKETFRQFEDIKANGPSSVGLDLSLHGFNHTYGVPEHADTLLLKDTSVSEAYRLYNLDVFGYEINSRLGLYGSVPLLLAHKPERTAGVFWLNSSETLVDVKYNTEQNEDEDEPPGKKSRISPRTDVRWISESGTIDCFILLGPTPAQVFSQYAQLTGKCRCRLYNGCARNRPLLSYQALPPLFSLGNHQCRWNYEDEADVKAVDAGFDLHGIPYDVIWLDIEHTDGKRYFTWDSKRFPNPAELQHHLMKKKRKLVVISDPHIKMDPDWSIYCEAKKGGHFVKNREGFDFEGTCWPGESCYLDFSSSKTRLWYARQFSLSKYEGSTESLFVWNDMNEPSVFNGPEQTMPKDALHHGGWEHRELHNLYGFYQHMATFEGLLTRSGGTERPFILTRSFFAGSQRLGAIWTGDNVATWEYLKISIPMLLSLSLTGIQFCGADVGGFVQDPDPELLVRWYQAGALQPFFRAHSAKMTKRREPWLFGEEVTSAIRSAVQDRYCLLPYWYTLFHQAHTAALPPIRPLWVEFPKDTSTFAVENQYMIGGALLVCPVTDPGVTEVKVLLPGSNELWYDTNTSEVHKGARSLDVPVTLTTVLVFQRGGTVVPRRTACGSCTADLQHYTITLTVALDIKGKADGFLYLDDGHSFNYRDQMQFCLRRFSMQAGRLVNSCANDKGLFVSDDKVETVVILGLKSVKRKPKLKSGAKRTSVMFEFDKKRGVLTLSGLELEICKDWEIII", "length": 916, "header": "tr|A0A8M9P9M8-1|A0A8M9P9M8_DANRE Isoform 1 of Neutral alpha-glucosidase C isoform X1 OS=Danio rerio OX=7955 GN=ganc PE=3 SV=1 CANONICAL=A0A8M9P9M8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HPE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8/entry#A0AC58HPE4-1", "sequence": { "sequence": "MKSYFTDGGASLELCERDSQDRLSLQIRATQNGTIRVSIDELQLVKPRYQVSDVLVGELRYEPLRVEWKKEDCVCLTWGLGQYQLLAFFSPFKLEISCAGEEIVTLNPGNKLCFETLQDPASRSSSNSSEGDENCCGLWKETFRQFEDIKANGPSSVGLDLSLHGFNHTYGVPEHADTLLLKDTSVSEAYRLYNLDVFGYEINSRLGLYGSVPLLLAHKPERTAGVFWLNSSETLVDVKYNTEQNEDEDEPPGKKSRISPRTDVRWISESGTIDCFILLGPTPAQVFSQYAQLTGYQALPPLFSLGNHQCRWNYEDEADVKAVDAGFDLHGIPYDVIWLDIEHTDGKRYFTWDSKRFPNPAELQHHLMKKKRKLVVISDPHIKMDPDWSIYCEAKKGGHFVKNREGFDFEGTCWPGESCYLDFSSSKTRLWYARQFSLSKYEGSTESLFVWNDMNEPSVFNGPEQTMPKDALHHGGWEHRELHNLYGFYQHMATFEGLLTRSGGTERPFILTRSFFAGSQRLGAIWTGDNVATWEYLKISIPMLLSLSLTGIQFCGADVGGFVQDPDPELLVRWYQAGALQPFFRAHSAKMTKRREPWLFGEEVTSAIRSAVQDRYCLLPYWYTLFHQAHTAALPPIRPLWVEFPKDTSTFAVENQYMIGGALLVCPVTDPGVTEVKVLLPGSNELWYDTNTSEVHKGARSLDVPVTLTTVLVFQRGGTVVPRRTACGSCTADLQHYTITLTVALDIKGKADGFLYLDDGHSFNYRDQMQFCLRRFSMQAGRLVNSCANDKGLFVSDDKVETVVILGLKSVKRKPKLKSGAKRTSVMFEFDKKRGVLTLSGLELEICKDWEIII", "length": 854, "header": "tr|A0AC58HPE4-1|A0AC58HPE4_DANRE Computationally mapped isoform of Neutral alpha-glucosidase C isoform X7 OS=Danio rerio OX=7955 GN=ganc PE=3 SV=1 CANONICAL=A0A8M9P9M8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HPE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8/entry#A0AC58HPE9-1", "sequence": { "sequence": "MKSYFTDGGASLELCERDSQDRLSLQIRATQNGTIRVSIDELQLVKPRYQVSDVLVGELRYEPLRVEWKKEDCVCLTWGLGQYQLLAFFSPFKLEISCAGEEIVTLNPGNKLCFETLQDPARSSSNSSEGDENCCGLWKETFRQFEDIKANGPSSVGLDLSLHGFNHTYGVPEHADTLLLKDTSVSEAYRLYNLDVFGYEINSRLGLYGSVPLLLAHKPERTAGVFWLNSSETLVDVKYNTEQNEDEDEPPGKKSRISPRTDVRWISESGTIDCFILLGPTPAQVFSQYAQLTGYQALPPLFSLGNHQCRWNYEDEADVKAVDAGFDLHGIPYDVIWLDIEHTDGKRYFTWDSKRFPNPAELQHHLMKKKRKLVVISDPHIKMDPDWSIYCEAKKGGHFVKNREGFDFEGTCWPGESCYLDFSSSKTRLWYARQFSLSKYEGSTESLFVWNDMNEPSVFNGPEQTMPKDALHHGGWEHRELHNLYGFYQHMATFEGLLTRSGGTERPFILTRSFFAGSQRLGAIWTGDNVATWEYLKISIPMLLSLSLTGIQFCGADVGGFVQDPDPELLVRWYQAGALQPFFRAHSAKMTKRREPWLFGEEVTSAIRSAVQDRYCLLPYWYTLFHQAHTAALPPIRPLWVEFPKDTSTFAVENQYMIGGALLVCPVTDPGVTEVKVLLPGSNELWYDTNTSEVHKGARSLDVPVTLTTVLVFQRGGTVVPRRTACGSCTADLQHYTITLTVALDIKGKADGFLYLDDGHSFNYRDQMQFCLRRFSMQAGRLVNSCANDKGLFVSDDKVETVVILGLKSVKRKPKLKSGAKRTSVMFEFDKKRGVLTLSGLELEICKDWEIII", "length": 853, "header": "tr|A0AC58HPE9-1|A0AC58HPE9_DANRE Computationally mapped isoform of Neutral alpha-glucosidase C isoform X8 OS=Danio rerio OX=7955 GN=ganc PE=3 SV=1 CANONICAL=A0A8M9P9M8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HPF8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8/entry#A0AC58HPF8-1", "sequence": { "sequence": "MKSYFTDGGASLELCERDSQDRLSLQIRATQNGTIRVSIDELQLVKPRYQVSDVLVGELRYEPLRVEWKKEDCVCLTWGLGQYQLLAFFSPFKLEISCAGEEIVTLNPGNKLCFETLQDPASRSSSNSSEGDENCCGLWKETFRQFEDIKANGPSSVGLDLSLHGFNHTYGVPEHADTLLLKDTSVSEAYRLYNLDVFGYEINSRLGLYGSVPLLLAHKPERTAGVFWLNSSETLVDVKYNTEQNEDEDEPPGKKSRISPRTDVRWISESGTIDCFILLGPTPAQVFSQYAQLTGKCRCRLYNGCARNRPLLSYQALPPLFSLGNHQCRWNYEDEADVKAVDAGFDLHGIPYDVIWLDIEHTDGKRYFTWDSKRFPNPAELQHHLMKKKRKLVVISDPHIKMDPDWSIYCEAKKGGHFVKNREGFDFEGTCWPGESCYLDFSSSKTRLWYARQFSLSKYEGSTESLFVWNDMNEPSVFNGPEQTMPKDALHHGGWEHRELHNLYGFYQHMATFEGLLTRSGGTERPFILTRSFFAGSQRLGAIWTGDNVATWEYLKISIPMLLSLSLTGIQFCGADVGGFVQDPDPELLVRWYQAGALQPFFRAHSAKMTKRREPWLFGEEVTSAIRSAVQDRYCLLPYWYTLFHQAHTAALPPIRPLWVEFPKDTSTFAVENQYMIGGALLVCPVTDPGVTEVKVLLPGSNELWYDTNTSEVHKGARSLDVPVTLTTVLVFQRGGTVVPRRTACGSCTADLQHYTITLTVALDIKGKADGFLYLDDGHSFNYRDQMQFCLRRFSMQAGRLVNSCANDKGLFVSDDKVETVVILGLKSVKRKPKLKSGAKRTSVMFEFDKKRGVLTLSGLELEICKDWEIII", "length": 872, "header": "tr|A0AC58HPF8-1|A0AC58HPF8_DANRE Computationally mapped isoform of Neutral alpha-glucosidase C isoform X5 OS=Danio rerio OX=7955 GN=ganc PE=3 SV=1 CANONICAL=A0A8M9P9M8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HPG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8/entry#A0AC58HPG1-1", "sequence": { "sequence": "MEVNVSTESIESVLKSEDKFRKNHEILFYRRQRDKAVSQYFTSYETFVLTDGGASLELCERDSQDRLSLQIRATQNGTIRVSIDELQLVKPRYQVSDVLVGELRYEPLRVEWKKEDCVCLTWGLGQYQLLAFFSPFKLEISCAGEEIVTLNPGNKLCFETLQDPARSSSNSSEGDENCCGLWKETFRQFEDIKANGPSSVGLDLSLHGFNHTYGVPEHADTLLLKDTSVSEAYRLYNLDVFGYEINSRLGLYGSVPLLLAHKPERTAGVFWLNSSETLVDVKYNTEQNEDEDEPPGKKSRISPRTDVRWISESGTIDCFILLGPTPAQVFSQYAQLTGKCRCRLYNGCARNRPLLSYQALPPLFSLGNHQCRWNYEDEADVKAVDAGFDLHGIPYDVIWLDIEHTDGKRYFTWDSKRFPNPAELQHHLMKKKRKLVVISDPHIKMDPDWSIYCEAKKGGHFVKNREGFDFEGTCWPGESCYLDFSSSKTRLWYARQFSLSKYEGSTESLFVWNDMNEPSVFNGPEQTMPKDALHHGGWEHRELHNLYGFYQHMATFEGLLTRSGGTERPFILTRSFFAGSQRLGAIWTGDNVATWEYLKISIPMLLSLSLTGIQFCGADVGGFVQDPDPELLVRWYQAGALQPFFRAHSAKMTKRREPWLFGEEVTSAIRSAVQDRYCLLPYWYTLFHQAHTAALPPIRPLWVEFPKDTSTFAVENQYMIGGALLVCPVTDPGVTEVKVLLPGSNELWYDTNTSEVHKGARSLDVPVTLTTVLVFQRGGTVVPRRTACGSCTADLQHYTITLTVALDIKGKADGFLYLDDGHSFNYRDQMQFCLRRFSMQAGRLVNSCANDKGLFVSDDKVETVVILGLKSVKRKPKLKSGAKRTSVMFEFDKKRGVLTLSGLELEICKDWEIII", "length": 915, "header": "tr|A0AC58HPG1-1|A0AC58HPG1_DANRE Computationally mapped isoform of Neutral alpha-glucosidase C isoform X2 OS=Danio rerio OX=7955 GN=ganc PE=3 SV=1 CANONICAL=A0A8M9P9M8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HPG2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8/entry#A0AC58HPG2-1", "sequence": { "sequence": "MEVNVSTESIESVLKSEDKFRKNHEILFYRRQRDKAVSQYFTSYETFVLTDGGASLELCERDSQDRLSLQIRATQNGTIRVSIDELQLVKPRYQVSDVLVGELRYEPLRVEWKKEDCVCLTWGLGQYQLLAFFSPFKLEISCAGEEIVTLNPGNKLCFETLQDPARSSSNSSEGDENCCGLWKETFRQFEDIKANGPSSVGLDLSLHGFNHTYGVPEHADTLLLKDTSVSEAYRLYNLDVFGYEINSRLGLYGSVPLLLAHKPERTAGVFWLNSSETLVDVKYNTEQNEDEDEPPGKKSRISPRTDVRWISESGTIDCFILLGPTPAQVFSQYAQLTGYQALPPLFSLGNHQCRWNYEDEADVKAVDAGFDLHGIPYDVIWLDIEHTDGKRYFTWDSKRFPNPAELQHHLMKKKRKLVVISDPHIKMDPDWSIYCEAKKGGHFVKNREGFDFEGTCWPGESCYLDFSSSKTRLWYARQFSLSKYEGSTESLFVWNDMNEPSVFNGPEQTMPKDALHHGGWEHRELHNLYGFYQHMATFEGLLTRSGGTERPFILTRSFFAGSQRLGAIWTGDNVATWEYLKISIPMLLSLSLTGIQFCGADVGGFVQDPDPELLVRWYQAGALQPFFRAHSAKMTKRREPWLFGEEVTSAIRSAVQDRYCLLPYWYTLFHQAHTAALPPIRPLWVEFPKDTSTFAVENQYMIGGALLVCPVTDPGVTEVKVLLPGSNELWYDTNTSEVHKGARSLDVPVTLTTVLVFQRGGTVVPRRTACGSCTADLQHYTITLTVALDIKGKADGFLYLDDGHSFNYRDQMQFCLRRFSMQAGRLVNSCANDKGLFVSDDKVETVVILGLKSVKRKPKLKSGAKRTSVMFEFDKKRGVLTLSGLELEICKDWEIII", "length": 897, "header": "tr|A0AC58HPG2-1|A0AC58HPG2_DANRE Computationally mapped isoform of Neutral alpha-glucosidase C isoform X4 OS=Danio rerio OX=7955 GN=ganc PE=3 SV=1 CANONICAL=A0A8M9P9M8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HPH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8/entry#A0AC58HPH1-1", "sequence": { "sequence": "MKSYFTDGGASLELCERDSQDRLSLQIRATQNGTIRVSIDELQLVKPRYQVSDVLVGELRYEPLRVEWKKEDCVCLTWGLGQYQLLAFFSPFKLEISCAGEEIVTLNPGNKLCFETLQDPARSSSNSSEGDENCCGLWKETFRQFEDIKANGPSSVGLDLSLHGFNHTYGVPEHADTLLLKDTSVSEAYRLYNLDVFGYEINSRLGLYGSVPLLLAHKPERTAGVFWLNSSETLVDVKYNTEQNEDEDEPPGKKSRISPRTDVRWISESGTIDCFILLGPTPAQVFSQYAQLTGKCRCRLYNGCARNRPLLSYQALPPLFSLGNHQCRWNYEDEADVKAVDAGFDLHGIPYDVIWLDIEHTDGKRYFTWDSKRFPNPAELQHHLMKKKRKLVVISDPHIKMDPDWSIYCEAKKGGHFVKNREGFDFEGTCWPGESCYLDFSSSKTRLWYARQFSLSKYEGSTESLFVWNDMNEPSVFNGPEQTMPKDALHHGGWEHRELHNLYGFYQHMATFEGLLTRSGGTERPFILTRSFFAGSQRLGAIWTGDNVATWEYLKISIPMLLSLSLTGIQFCGADVGGFVQDPDPELLVRWYQAGALQPFFRAHSAKMTKRREPWLFGEEVTSAIRSAVQDRYCLLPYWYTLFHQAHTAALPPIRPLWVEFPKDTSTFAVENQYMIGGALLVCPVTDPGVTEVKVLLPGSNELWYDTNTSEVHKGARSLDVPVTLTTVLVFQRGGTVVPRRTACGSCTADLQHYTITLTVALDIKGKADGFLYLDDGHSFNYRDQMQFCLRRFSMQAGRLVNSCANDKGLFVSDDKVETVVILGLKSVKRKPKLKSGAKRTSVMFEFDKKRGVLTLSGLELEICKDWEIII", "length": 871, "header": "tr|A0AC58HPH1-1|A0AC58HPH1_DANRE Computationally mapped isoform of Neutral alpha-glucosidase C isoform X6 OS=Danio rerio OX=7955 GN=ganc PE=3 SV=1 CANONICAL=A0A8M9P9M8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HPK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8/entry#A0AC58HPK4-1", "sequence": { "sequence": "MKKKRKLVVISDPHIKMDPDWSIYCEAKKGGHFVKNREGFDFEGTCWPGESCYLDFSSSKTRLWYARQFSLSKYEGSTESLFVWNDMNEPSVFNGPEQTMPKDALHHGGWEHRELHNLYGFYQHMATFEGLLTRSGGTERPFILTRSFFAGSQRLGAIWTGDNVATWEYLKISIPMLLSLSLTGIQFCGADVGGFVQDPDPELLVRWYQAGALQPFFRAHSAKMTKRREPWLFGEEVTSAIRSAVQDRYCLLPYWYTLFHQAHTAALPPIRPLWVEFPKDTSTFAVENQYMIGGALLVCPVTDPGVTEVKVLLPGSNELWYDTNTSEVHKGARSLDVPVTLTTVLVFQRGGTVVPRRTACGSCTADLQHYTITLTVALDIKGKADGFLYLDDGHSFNYRDQMQFCLRRFSMQAGRLVNSCANDKGLFVSDDKVETVVILGLKSVKRKPKLKSGAKRTSVMFEFDKKRGVLTLSGLELEICKDWEIII", "length": 487, "header": "tr|A0AC58HPK4-1|A0AC58HPK4_DANRE Computationally mapped isoform of Neutral alpha-glucosidase C isoform X9 OS=Danio rerio OX=7955 GN=ganc PE=3 SV=1 CANONICAL=A0A8M9P9M8-1" }, "locus": {} }, { "isoform_ac": "E7F6D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8/entry#E7F6D4-1", "sequence": { "sequence": "MEVNVSTESIESVLKSEDKFRKNHEILFYRRQRDKAVSQYFTSYETFVLTDGGASLELCERDSQDRLSLQIRATQNGTIRVSIDELQLVKPRYQVSDVLVGELRYEPLRVEWKKEDCVCLTWGLGQYQLLAFFSPFKLEISCAGEEIVTLNPGNKLCFETLQDPASRSSSNSSEGDENCCGLWKETFRQFEDIKANGPSSVGLDLSLHGFNHTYGVPEHADTLLLKDTSVSEAYRLYNLDVFGYEINSRLGLYGSVPLLLAHKPERTAGVFWLNSSETLVDVKYNTEQNEDEDEPPGKKSRISPRTDVRWISESGTIDCFILLGPTPAQVFSQYAQLTGYQALPPLFSLGNHQCRWNYEDEADVKAVDAGFDLHGIPYDVIWLDIEHTDGKRYFTWDSKRFPNPAELQHHLMKKKRKLVVISDPHIKMDPDWSIYCEAKKGGHFVKNREGFDFEGTCWPGESCYLDFSSSKTRLWYARQFSLSKYEGSTESLFVWNDMNEPSVFNGPEQTMPKDALHHGGWEHRELHNLYGFYQHMATFEGLLTRSGGTERPFILTRSFFAGSQRLGAIWTGDNVATWEYLKISIPMLLSLSLTGIQFCGADVGGFVQDPDPELLVRWYQAGALQPFFRAHSAKMTKRREPWLFGEEVTSAIRSAVQDRYCLLPYWYTLFHQAHTAALPPIRPLWVEFPKDTSTFAVENQYMIGGALLVCPVTDPGVTEVKVLLPGSNELWYDTNTSEVHKGARSLDVPVTLTTVLVFQRGGTVVPRRTACGSCTADLQHYTITLTVALDIKGKADGFLYLDDGHSFNYRDQMQFCLRRFSMQAGRLVNSCANDKGLFVSDDKVETVVILGLKSVKRKPKLKSGAKRTSVMFEFDKKRGVLTLSGLELEICKDWEIII", "length": 898, "header": "tr|E7F6D4-1|E7F6D4_DANRE Computationally mapped isoform of Neutral alpha-glucosidase C isoform X3 OS=Danio rerio OX=7955 GN=ganc PE=3 SV=1 CANONICAL=A0A8M9P9M8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 326, "start_aa": "Thr", "end_pos": 326, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr326", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100536353", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536353", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7G933-1", "protein_name": "Neutral alpha-glucosidase C isoform X1", "gene_name": "Ganc", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEAAEKEEISVEDEAVDKTIFRDCSEIAFYRRQKQQLSKNTTYQALLDSVTTEQDSTRFQIISEANKTPLLVEVYGIEKNIFRLKINEETPLKPRYEVPDVITSKLRTVRLVSCPGDAGSLILTDGKGDLKCHISANPFKVDLVSENEAVISINSLGQLYFEHLQIPHKQSRATKGNQESAPADTSQENQEDLGLWEEKFGKFVDVKANGPSSIGLDFSFHGFEHLYGIPQHAESHQLKNTRDGDAYRLYNLDVYGYQIHDKMGIYGSVPYLLAHKQGKTVAIFWLNASETLVEINTEPAVEYTLTQTGAAAAKQKVRCRTDVRWMSESGIIDVFLLTGPTPSDIFKQYSSLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHGIPYDVMWLDIEHTEDKKYFTWDKKRFANPRRMQELLRSKKRKLVVISDPHIKVDPDYSVYAKAKEQGFFVKNPEGGDFEGVCWPGLSSYLDFTNPKVREWYSGLFAFPVYQGSTDILFIWNDMNEPSVFRGPELTMQKNAVHYGNWEHRELHNMYGFYQQMATAEGLIRRSKGQERPFVLSRSFFAGSQKYGAVWTGDNAAEWNYLKISIPMLLTLSVSGISFCGADVGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEYTRLIREAIRERYTLLPYLYSLFYRVHMSSEPVMRPLWVEFPDDLETFSVDDEYMLGSALLVHPITEPQTTMADIFLPGSNEVWYDSKTFAQWKGGCTVKIPVTLDTIPVFQRGGSVVPIKTSVGKSTGWMTDSPYGLRLALSTQDSAEGELYLDDGHSFQYLHQDQFLHRRFSFCSGVLINRCADEKGHYPSKCIVEQILVLGLRKKPSSVTTRSSDGKVQPAAFTYHTKASALSLEKLSLSITDDWEVHIR", "length": 915 }, "evidence": [ { "id": "A0A8M9P9M8", "url": "https://omabrowser.org/oma/group/A0A8M9P9M8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9RXE5-1", "protein_name": "Glucosidase alpha, neutral C", "gene_name": "GANC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESAEKEEISVEDEAVDKNVFKDCSKIAFYRRQKQLLSKKSTYRALLDSVTPGEDSARFQIINEPAKVPLLAEVCGIEGNIFRLKINEEIPLKPRYEVPDVLTSKLTTVRLTSCPGDTGSLVLASGKGDLKCHITANPFKVDLVSEEEVVMSINSLGQLYFEQLQIPPKQRATKKNEEDASIDTTQENQEELGLWEEKFENFVDVKVNGPASIGLDFSLHGFEHLYGIPQHAESHQLKNTSDSDAYRLYNLDVYGYKIHDKMGIYGSVPYLLAHKLGRTLGIFWLNASETLVEIKTEPAVKYTLTQTGPVAAKQKVGSRTDVHWMSESGIIDVFLLTGPTPSDVFKQYSYLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDVMWLDIEHTEGKRYFTWDKKRFPNPKRMQDLLRSKKRKLVVISDPHVKVDPNYSVYAKAKEQGFFVRNHEGGDFEGVCWPGLSSYLDFTNPKVRKWYSSLFAFSVYQGSTDILHIWNDMNEPSVFKGPEQTMQKNAIHHGNWEHRELHNIYGFYQQMATTEGLIQRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSHLKISIPMLLTLSVTGISFCGADVGGFIGDPEAELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEHTRLIREAIRERYTLLPYWYSLFYSAHVASQPVMRPLWVEFPNELETFSVEDEYMLGGALLVHPVTEPKATVVDVFLPGSSEIWYDSKTFAHWKGACTVKIPVTLDAIPVFQRGGSVVPIKTTIGRSTGFMTNSPYGLRVALSTKGSAMGEFYLDDGHSFQYLHQKQFLHRKFSFSSGVLTNSCADERGHYPSKCVVEQILVLGLKKQPSSVTAHSADGSAQPVAFTYHATTSTLKLETLSLNIGADWKVRVQ", "length": 914 }, "evidence": [ { "id": "A0A8M9P9M8", "url": "https://omabrowser.org/oma/group/A0A8M9P9M8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AC58JGY4-1", "protein_name": "Neutral alpha-glucosidase AB", "gene_name": "ganaba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQMTAVVELCFVLLLFLLFVSAQAVDRSNFKTCDQSSFCKRQRELKPGQSPYRALLDTLELSDSRLTLQLINDNNKVRLLLELYRLQGNMTRVKINELKPIKPRYEVPDVLISDPITEALSVVSQDDNSLVLSLGGNEQRLIVSAQPFRLDIIEGPQVLMSLNSRGLLAFEHLRVRKDTISHKISSTVGSMWDSIKSVFSSNSESEETTGQQKEEQPTSEDGQIKEEEEEKPGMWEETFKSHSDSKPNGPSSISLDFSLPGVEHVYGIPEHADTLRLKSTENSDPYRLYNLDVFQYELHNPMALYGAVPVLISHSTERTMGIFWLNAAETWVDISSNSPDTVSSDAPQTNVRWVSESGIIDVFIMLGPKPADVFTQYASLTGTQSFPPLSALAYHQCRWNYNDQEDVKAVDQGFDEHDIPYDFIWLDIEHADGKRYFTWDPIKFPTPKDMLKGLMDKRRKLVAIVDPHIRVDSGYRIHNEIRSKNFYVKNKDGGDYEGWCWPGNSGYPDFTNPEMRAWWASMFAYDQYEGSMENQYIWNDMNEPSVFNGPEVTMHKDAVHGVWEHRDVHNLYGLYVQKATSEGLIQRSGGVERPFVLTRAFFAGSQRYGAVWTGDNAAEWGHLKISIPMCLSLGLVGISFCGADVGGFFKHPSAELLVRWYQAGAYQPFFRAHAHIDTPRREPWLFGPENTALIREAVRQRYALLPYWYQLFYNAHNTGQPVMRPLWVEYPAEVITFSIEDEYLIGKDLLVHPVTDEGATGVTAYLPGKGEVWYDVHSLQKHDGDQSLYIPVTMSSIPVFQRGGSIICRKERIRRSSSCMENDPYTLYVALNPQGFAEGELYIDDFHTFNYQKSKQFIHRRLSFSNNSLTSRNLAPDAQFSTESWIERIVVIGGSRPSSVSLISADGVESALEFEFSSNPAVLTVRKPSVSAAADWTVVLRREQFINVYKHLGVRKLGDFWVNYLFKRKDSDWSIFNEKRKLKSAM", "length": 986 }, "evidence": [ { "id": "SGD:S000000433", "url": "https://alliancegenome.org/gene/SGD:S000000433#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZAN3-1", "protein_name": "Neutral alpha-glucosidase AB", "gene_name": "Ganab", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAIAAVAARRRRSWLSLVLAYLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLTHEVTKVLLVLELQGLQKNMTRIRIDELEPRRPRYRVPDVLVADPATARLSISGRDDNSVELTVAEGPYKIILTAKPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPFSDKVSLTLGSMWDKIKNLFSRQEPKDAAEGNGAEPEARPGDGDKAKETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIVDVFLMLGPSVLDVFRQHASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPQMRAWWANMFNFHNYEGSAPNLFVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHQEGFPVMRPLWVQYPEDMSTFSMEDQFMLGDALLIHPVSDAGAHGVQVYLPGEEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKEDPITLFVALSAQGTAQGELFLDDGHTFNYQNRHEFLLRRFSFSGNTLVSSSADPKGHLETPVWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLTLRKPGVNVASDWSIHLR", "length": 966 }, "evidence": [ { "id": "SGD:S000000433", "url": "https://alliancegenome.org/gene/SGD:S000000433#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A7G5-1", "protein_name": "Glucosidase, alpha; neutral C", "gene_name": "Ganc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METPEKKEISVEDEAVDKTIFKDCGKIAFYRRQKQQLSKNTTYRASLGSVSTEQDSTRFQISSEATKIPLVAEVYGIEKDIFRLKINEETPLKPRYEVPDVVNSKLGTVRLVCSGDTGSLTLTDRKGDLRCHISANPFKIDLLSKDEALISINSLGKLYFEHLRVPHKQRATKGNGQNTPADTFQENQEDLGLWEEKFGKFVDVKVNGPSSVGLDFSLHGFEHLYGIPQHAESHQLKNTRDGDAYRLYNLDVYGYQVHDKMGIYGSVPYLLAHKQGRTVGIFWLNASETLVEINTEPAAEYTLTQMGPAAAKQKVRCRTNVHWMSESGIIDVFLLTGPTPADIFKQYSYITGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDVMWLDIEHTEDKKYFTWDKKRFANPKRMQELLRSKGRKLVVISDPHIKVDPDYTVYAEAKERGFFVKNPEGGDLEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPELTMQKNAVHHGNWEHRELHNIYGFYHQMATAEGLIQRSQGKERPFVLSRSFFAGSQKYGAVWTGDNTAEWSYLKISIPMLLTLSVSGISFCGADVGGFIGNPEAELLVRWYQAAAYQPFFRGHATMNTKRREPWLFGAEYTQLIREAIRERYSLLPYLYSLFYHAHVSSQPVMRPLWVEFPDDLETFAVEDEYMLGNALLVHPVTAPQTTMIDVFLPGSNEVWYNSKTFAYWKGGCAVKVPVTLDTIPVFQRGGSVVPVKTTVGKSTGWMTDSPYGLRVALNTQGSAVGELYLDDGHSFQYLHQNQFLHRKFLFCSSVLTNRCADEKGHYPSKCIVEQILVLGLKKKPSSVTTHSSDGKVQPATFAYCAKTCTLSLKKLSLSVGDDWEVHVS", "length": 913 }, "evidence": [ { "id": "MGI:1923301", "url": "https://alliancegenome.org/gene/MGI:1923301#orthology", "database": "AGR" }, { "id": "HGNC:4139", "url": "https://alliancegenome.org/gene/HGNC:4139#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-754", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-754#orthology", "database": "AGR" }, { "id": "RGD:2660", "url": "https://alliancegenome.org/gene/RGD:2660#orthology", "database": "AGR" }, { "id": "SGD:S000000433", "url": "https://alliancegenome.org/gene/SGD:S000000433#orthology", "database": "AGR" }, { "id": "A0A8M9P9M8", "url": "https://omabrowser.org/oma/group/A0A8M9P9M8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38138-1", "protein_name": "Glucosidase 2 subunit alpha", "gene_name": "ROT2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVLLKWLVCQLVFFTAFSHAFTDYLLKKCAQSGFCHRNRVYAENIAKSHHCYYKVDAESIAHDPLENVLHATIIKTIPRLEGDDIAVQFPFSLSFLQDHSVRFTINEKERMPTNSSGLLISSQRFNETWKYAFDKKFQEEANRTSIPQFHFLKQKQTVNSFWSKISSFLSLSNSTADTFHLRNGDVSVEIFAEPFQLKVYWQNALKLIVNEQNFLNIEHHRTKQENFAHVLPEETTFNMFKDNFLYSKHDSMPLGPESVALDFSFMGSTNVYGIPEHATSLRLMDTSGGKEPYRLFNVDVFEYNIGTSQPMYGSIPFMFSSSSTSIFWVNAADTWVDIKYDTSKNKTMTHWISENGVIDVVMSLGPDIPTIIDKFTDLTGRPFLPPISSIGYHQCRWNYNDEMDVLTVDSQMDAHMIPYDFIWLDLEYTNDKKYFTWKQHSFPNPKRLLSKLKKLGRNLVVLIDPHLKKDYEISDRVINENVAVKDHNGNDYVGHCWPGNSIWIDTISKYGQKIWKSFFERFMDLPADLTNLFIWNDMNEPSIFDGPETTAPKDLIHDNYIEERSVHNIYGLSVHEATYDAIKSIYSPSDKRPFLLTRAFFAGSQRTAATWTGDNVANWDYLKISIPMVLSNNIAGMPFIGADIAGFAEDPTPELIARWYQAGLWYPFFRAHAHIDTKRREPYLFNEPLKSIVRDIIQLRYFLLPTLYTMFHKSSVTGFPIMNPMFIEHPEFAELYHIDNQFYWSNSGLLVKPVTEPGQSETEMVFPPGIFYEFASLHSFINNGTDLIEKNISAPLDKIPLFIEGGHIITMKDKYRRSSMLMKNDPYVIVIAPDTEGRAVGDLYVDDGETFGYQRGEYVETQFIFENNTLKNVRSHIPENLTGIHHNTLRNTNIEKIIIAKNNLQHNITLKDSIKVKKNGEESSLPTRSSYENDNKITILNLSLDITEDWEVIF", "length": 954 }, "evidence": [ { "id": "MGI:1923301", "url": "https://alliancegenome.org/gene/MGI:1923301#orthology", "database": "AGR" }, { "id": "HGNC:4139", "url": "https://alliancegenome.org/gene/HGNC:4139#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-754", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-754#orthology", "database": "AGR" }, { "id": "RGD:2660", "url": "https://alliancegenome.org/gene/RGD:2660#orthology", "database": "AGR" }, { "id": "SGD:S000000433", "url": "https://alliancegenome.org/gene/SGD:S000000433#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q14697-1", "protein_name": "Neutral alpha-glucosidase AB", "gene_name": "GANAB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVAAVAARRRRSWASLVLAFLGVCLGITLAVDRSNFKTCEESSFCKRQRSIRPGLSPYRALLDSLQLGPDSLTVHLIHEVTKVLLVLELQGLQKNMTRFRIDELEPRRPRYRVPDVLVADPPIARLSVSGRDENSVELTMAEGPYKIILTARPFRLDLLEDRSLLLSVNARGLLEFEHQRAPRVSQGSKDPAEGDGAQPEETPRDGDKPEETQGKAEKDEPGAWEETFKTHSDSKPYGPMSVGLDFSLPGMEHVYGIPEHADNLRLKVTEGGEPYRLYNLDVFQYELYNPMALYGSVPVLLAHNPHRDLGIFWLNAAETWVDISSNTAGKTLFGKMMDYLQGSGETPQTDVRWMSETGIIDVFLLLGPSISDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNLPCDVIWLDIEHADGKRYFTWDPSRFPQPRTMLERLASKRRKLVAIVDPHIKVDSGYRVHEELRNLGLYVKTRDGSDYEGWCWPGSAGYPDFTNPTMRAWWANMFSYDNYEGSAPNLFVWNDMNEPSVFNGPEVTMLKDAQHYGGWEHRDVHNIYGLYVHMATADGLRQRSGGMERPFVLARAFFAGSQRFGAVWTGDNTAEWDHLKISIPMCLSLGLVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLPSQHNDIIRDALGQRYSLLPFWYTLLYQAHREGIPVMRPLWVQYPQDVTTFNIDDQYLLGDALLVHPVSDSGAHGVQVYLPGQGEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSECMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRQEFLLRRFSFSGNTLVSSSADPEGHFETPIWIERVVIIGAGKPAAVVLQTKGSPESRLSFQHDPETSVLVLRKPGINVASDWSIHLR", "length": 944 }, "evidence": [ { "id": "SGD:S000000433", "url": "https://alliancegenome.org/gene/SGD:S000000433#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BHN3-1", "protein_name": "Neutral alpha-glucosidase AB", "gene_name": "Ganab", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAIAAVAARRRRSWLSLVLAYLGVCLGITLAVDRSNFKTCDESSFCKRQRSIRPGLSPYRALLDTLQLGPDALTVHLIHEVTKVLLVLELQGLQKNMTRIRIDELEPRRPRYRVPDVLVADPPTARLSVSGRDDNSVELTVAEGPYKIILTAQPFRLDLLEDRSLLLSVNARGLMAFEHQRAPRVPQESKDPAEGNGAQPEATPGDGDKPEETQEKAEKDEPGAWEETFKTHSDSKPYGPTSVGLDFSLPGMEHVYGIPEHADSLRLKVTEGGEPYRLYNLDVFQYELNNPMALYGSVPVLLAHSFHRDLGIFWLNAAETWVDISSNTAGKTLFGKMLDYLQGSGETPQTDIRWMSESGIIDVFLMLGPSVFDVFRQYASLTGTQALPPLFSLGYHQSRWNYRDEADVLEVDQGFDDHNMPCDVIWLDIEHADGKRYFTWDPTRFPQPLNMLEHLASKRRKLVAIVDPHIKVDSGYRVHEELRNHGLYVKTRDGSDYEGWCWPGSASYPDFTNPRMRAWWSNMFSFDNYEGSAPNLYVWNDMNEPSVFNGPEVTMLKDAVHYGGWEHRDIHNIYGLYVHMATADGLIQRSGGIERPFVLSRAFFSGSQRFGAVWTGDNTAEWDHLKISIPMCLSLALVGLSFCGADVGGFFKNPEPELLVRWYQMGAYQPFFRAHAHLDTGRREPWLLASQYQDAIRDALFQRYSLLPFWYTLFYQAHKEGFPVMRPLWVQYPEDMSTFSIEDQFMLGDALLIHPVSDAGAHGVQVYLPGQEEVWYDIQSYQKHHGPQTLYLPVTLSSIPVFQRGGTIVPRWMRVRRSSDCMKDDPITLFVALSPQGTAQGELFLDDGHTFNYQTRHEFLLRRFSFSGSTLVSSSADPKGHLETPIWIERVVIMGAGKPAAVVLQTKGSPESRLSFQHDPETSVLILRKPGVSVASDWSIHLR", "length": 944 }, "evidence": [ { "id": "SGD:S000000433", "url": "https://alliancegenome.org/gene/SGD:S000000433#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BVW0-1", "protein_name": "Neutral alpha-glucosidase C", "gene_name": "Ganc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAAEKEEISVEDEAVDKTIFKDCGKIAFYRRQKQQLTKTTTYQALLGSVDTEQDSTRFQIISEATKIPLVAEVYGIEKDIFRLKINEETPLKPRLVCSGDTGSLILTNRKGDLKCHVSANPFKIDLLSKNEAVISINSLGQLYFEHLQVPHKQRATKGNGQNTPAATSQENQEDLGLWEEKFGKFVDVKANGPSSVGLDFSLHGFEHLYGIPQHAESHQLKNTRDGDAYRLYNLDVYGYQVHDKMGIYGSVPYLLAHKQGRTVGIFWLNASETLVEINTEPAVEYTLTQMGPAAAKPKVRCRTDVHWMSESGIIDVFLLTGPTPADVFKQYSYITGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDVMWLDIEHTEDKKYFTWDKKRFANPKRMQELLRSKKRKLVVISDPHIKVDPDYTVYAQAKEQGFFVKNPEGGDFEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPELTMHKSAVHYGDWEHRELHNIYGFYQQMATAEGLIQRSKGKERPFVLSRSFFAGSQKYGAVWTGDNKAEWSYLKISIPMLLTLSVSGISFCGADVGGFIGNPEAELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEYTQLIREAIRQRYALLPYLYSLFYHTHVSSQPVMRPLWVEYPDDLETFAVEDEYMLGSALLVHPVTDPQTATIDVFLPGSDEVWYDSKTFAYWKGGCTVKIPVTLDTIPVFQRGGSVVPVKTTVGTSTGWMADSPYELRVALSTQGSAVGELYLDDGHSFQYLHQNQFLYRKFLFCSSVLTNRCANEKGHYPSKCIVEQILVLGLKKKPSSVTTHLSDGRAQPAAFTYCAETSALRLEKLSLRIGEDWEVRVG", "length": 898 }, "evidence": [ { "id": "MGI:1923301", "url": "https://alliancegenome.org/gene/MGI:1923301#orthology", "database": "AGR" }, { "id": "HGNC:4139", "url": "https://alliancegenome.org/gene/HGNC:4139#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-754", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-754#orthology", "database": "AGR" }, { "id": "RGD:2660", "url": "https://alliancegenome.org/gene/RGD:2660#orthology", "database": "AGR" }, { "id": "SGD:S000000433", "url": "https://alliancegenome.org/gene/SGD:S000000433#orthology", "database": "AGR" }, { "id": "A0A8M9P9M8", "url": "https://omabrowser.org/oma/group/A0A8M9P9M8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TET4-1", "protein_name": "Neutral alpha-glucosidase C", "gene_name": "GANC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAAVKEEISLEDEAVDKNIFRDCNKIAFYRRQKQWLSKKSTYQALLDSVTTDEDSTRFQIINEASKVPLLAEIYGIEGNIFRLKINEETPLKPRFEVPDVLTSKPSTVRLISCSGDTGSLILADGKGDLKCHITANPFKVDLVSEEEVVISINSLGQLYFEHLQILHKQRAAKENEEETSVDTSQENQEDLGLWEEKFGKFVDIKANGPSSIGLDFSLHGFEHLYGIPQHAESHQLKNTGDGDAYRLYNLDVYGYQIYDKMGIYGSVPYLLAHKLGRTIGIFWLNASETLVEINTEPAVEYTLTQMGPVAAKQKVRSRTHVHWMSESGIIDVFLLTGPTPSDVFKQYSHLTGTQAMPPLFSLGYHQCRWNYEDEQDVKAVDAGFDEHDIPYDAMWLDIEHTEGKRYFTWDKNRFPNPKRMQELLRSKKRKLVVISDPHIKIDPDYSVYVKAKDQGFFVKNQEGEDFEGVCWPGLSSYLDFTNPKVREWYSSLFAFPVYQGSTDILFLWNDMNEPSVFRGPEQTMQKNAIHHGNWEHRELHNIYGFYHQMATAEGLIKRSKGKERPFVLTRSFFAGSQKYGAVWTGDNTAEWSNLKISIPMLLTLSITGISFCGADIGGFIGNPETELLVRWYQAGAYQPFFRGHATMNTKRREPWLFGEEHTRLIREAIRERYGLLPYWYSLFYHAHVASQPVMRPLWVEFPDELKTFDMEDEYMLGSALLVHPVTEPKATTVDVFLPGSNEVWYDYKTFAHWEGGCTVKIPVALDTIPVFQRGGSVIPIKTTVGKSTGWMTESSYGLRVALSTKGSSVGELYLDDGHSFQYLHQKQFLHRKFSFCSSVLINSFADQRGHYPSKCVVEKILVLGFRKEPSSVTTHSSDGKDQPVAFTYCAKTSILSLEKLSLNIATDWEVRII", "length": 914 }, "evidence": [ { "id": "MGI:1923301", "url": "https://alliancegenome.org/gene/MGI:1923301#orthology", "database": "AGR" }, { "id": "HGNC:4139", "url": "https://alliancegenome.org/gene/HGNC:4139#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-754", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-754#orthology", "database": "AGR" }, { "id": "RGD:2660", "url": "https://alliancegenome.org/gene/RGD:2660#orthology", "database": "AGR" }, { "id": "SGD:S000000433", "url": "https://alliancegenome.org/gene/SGD:S000000433#orthology", "database": "AGR" }, { "id": "A0A8M9P9M8", "url": "https://omabrowser.org/oma/group/A0A8M9P9M8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "alpha-1,4-glucosidase activity", "id": "GO:0004558", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004558", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8" } ], "pmid": "" }, { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8" } ], "pmid": "" }, { "name": "alpha-glucosidase activity", "id": "GO:0090599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090599", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8" } ], "pmid": "" }, { "name": "N-glycan processing", "id": "GO:0006491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006491", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9M8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 753, "end_pos": 755, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P9M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8" }, { "id": "PF13802", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13802" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycoside hydrolase family 31 N-terminal", "eco_id": "ECO_0000259", "start_pos": 69, "end_pos": 281, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P9M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8" }, { "id": "PF01055", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01055" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycoside hydrolase family 31 TIM barrel", "eco_id": "ECO_0000259", "start_pos": 360, "end_pos": 687, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9P9M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9M8" }, { "id": "PF21365", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21365" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl hydrolase family 31 C-terminal", "eco_id": "ECO_0000259", "start_pos": 696, "end_pos": 783, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 326 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 753, "end_pos": 755 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9P9Q7-1", "uniprot_ac": "A0A8M9P9Q7", "uniprot_id": "A0A8M9P9Q7_DANRE", "mass": { "chemical_mass": 71582.0, "monoisotopic_mass": 71582.0 }, "refseq": { "ac": "XP_021323188", "name": "guanylate-binding protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323188" }, "gene_names": [ { "name": "unm_sa911", "type": "recommended", "evidence": [ { "id": "A0A8M9P9Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9Q7" } ] }, { "name": "unm_sa911", "type": "synonym", "evidence": [ { "id": "XP_021323188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323188" } ] } ], "protein_names": [ { "name": "Guanylate-binding protein 4", "type": "synonym", "evidence": [ { "id": "A0A8M9P9Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9Q7/entry#names_and_taxonomy" } ] }, { "name": "guanylate-binding protein 4", "type": "synonym", "evidence": [ { "id": "XP_021323188", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323188" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323188" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9Q7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "unm_sa911", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9Q7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120727-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120727-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P9Q7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P9Q7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01851", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01851", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100334992", "url": "https://www.ncbi.nlm.nih.gov/gene/100334992", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003191", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003191", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015894", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015894", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036543", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036543", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037684", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037684", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100334992", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100334992", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P9Q7", "url": "https://www.orthodb.org/?gene=A0A8M9P9Q7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02263", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02263", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02841", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02841", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323188", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323188", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P9Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P9Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120727-3", "url": "https://zfin.org/ZDB-GENE-120727-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDSPVCLIDTASDGKLCVQPAALQILQQIQQPVVVVAVVGLYRTGKSYLLNRLAGKHSGFALGSTVESKTKGIWMWCVPHPTKAETTLLLLDTEGLGDVDKGDSRHDSNIFSLAVLLSSTLVFNSRGTIDNKAIEELQYVTELTECIKVKSPNEDVDNSTEFVKFFPSFIWAVRDFSLELKIDGEDATEDQYLEFALKLKHGTSKKVMEFNLPRECIKNFFPSRTCFTFPFPTTLEKMSTLERLGPADLCPEFQEVSKRFCTCVYEKSEVKRLKDGHTVTGRVLGHLAELYVNTISSGAVPCLENAVVALAQIENQAALQEALQVYQVGMEEKKRAFPLELEQVSAEHQRLSQSATQTFMAESFRDTDGKHLKALEEEINKLFDACLRENDQASVKKCENLLLSLSATMTEKHKQGFYAKPGGYDVFCRDLEDIVKKYNSLVKKEVKAEVVLQEFLKLKSVDSKAILQADRKLSEKEKKIKEETERAVLLEQEVKAKEETQRQLKERMEVEQRSNAERMQQMKLKMEQELEQQRVEAQRALDSKLKEQAALMEKGFQDKADLMKQEMEEFKQQASDAENSRSRELKELMENTNRRHEEQMKMMMEQHRQQMREIQRSSGGGSGLLCSVM", "length": 629, "header": "tr|A0A8M9P9Q7-1|A0A8M9P9Q7_DANRE Isoform 1 of Guanylate-binding protein 4 OS=Danio rerio OX=7955 GN=unm_sa911 PE=3 SV=1 CANONICAL=A0A8M9P9Q7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P9Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9Q7/entry#A0A8M9P9Q7-1", "sequence": { "sequence": "MDSPVCLIDTASDGKLCVQPAALQILQQIQQPVVVVAVVGLYRTGKSYLLNRLAGKHSGFALGSTVESKTKGIWMWCVPHPTKAETTLLLLDTEGLGDVDKGDSRHDSNIFSLAVLLSSTLVFNSRGTIDNKAIEELQYVTELTECIKVKSPNEDVDNSTEFVKFFPSFIWAVRDFSLELKIDGEDATEDQYLEFALKLKHGTSKKVMEFNLPRECIKNFFPSRTCFTFPFPTTLEKMSTLERLGPADLCPEFQEVSKRFCTCVYEKSEVKRLKDGHTVTGRVLGHLAELYVNTISSGAVPCLENAVVALAQIENQAALQEALQVYQVGMEEKKRAFPLELEQVSAEHQRLSQSATQTFMAESFRDTDGKHLKALEEEINKLFDACLRENDQASVKKCENLLLSLSATMTEKHKQGFYAKPGGYDVFCRDLEDIVKKYNSLVKKEVKAEVVLQEFLKLKSVDSKAILQADRKLSEKEKKIKEETERAVLLEQEVKAKEETQRQLKERMEVEQRSNAERMQQMKLKMEQELEQQRVEAQRALDSKLKEQAALMEKGFQDKADLMKQEMEEFKQQASDAENSRSRELKELMENTNRRHEEQMKMMMEQHRQQMREIQRSSGGGSGLLCSVM", "length": 629, "header": "tr|A0A8M9P9Q7-1|A0A8M9P9Q7_DANRE Isoform 1 of Guanylate-binding protein 4 OS=Danio rerio OX=7955 GN=unm_sa911 PE=3 SV=1 CANONICAL=A0A8M9P9Q7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "A0A8M9P9Q7", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M9P9Q7" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0A8M9P9Q7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M9P9Q7" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:100334992", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100334992", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JDV3-1", "protein_name": "Guanylate-binding protein 6", "gene_name": "Gbp6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTQPQMAPICLVENHNEQLSVNQEAIEILDKISQPVVVVAIVGLYRTGKSYLMNCLAGQNHGFPLGSTVQSQTKGIWMWCMPHPTKPEHTLVLLDTEGLGDVEKGDPKNDLWIFALSVLLSSTFIYNSMITINHQALEQLQYVTELTELIRAKSSPNPAGIKNSTEFVSFFPDFVWTVRDFMLELKLNGEDITSDDYLENALKLIPGDKPRMQASNSCRECIRLFFPNRKCFVFDRPTHDKELLQKLDSITEDQLDPKFQEVTKAFVSYIFTYAKIKTLKEGIKVTGNRLGILVTTYVNAINSGAVPCLDDAVTTLAQRENSVAVQKAADHYSEQMAQRLRLPTETLQELLDVHAACEKEAMAVFMEHSFKDENQQFLKKLVELIGENKELFLSKNEEASNKYCQEELDRLSKDFMENISTFFVPCGHKLYMDKREKIEHDYWQVPRKGVKASEVFQSFLQSQAFIESSILQADTALTAGEKAIAEERAQKVAAEKEQELLRQKQKEQQEYMEAQEKSHKENLEQLRRKLEQEREQDIKDHDMMLKKLMKDQKAFLEEGFKKKAEEMNKEIQQLRDVIKDKKRNTDRIKEALLNGFSTVLFHYLVRYLKHL", "length": 611 }, "evidence": [ { "id": "RGD:1561523", "url": "https://alliancegenome.org/gene/RGD:1561523#orthology", "database": "AGR" }, { "id": "HGNC:25395", "url": "https://alliancegenome.org/gene/HGNC:25395#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JTZ9-1", "protein_name": "ATP-binding cassette, subfamily G (WHITE), member 3-like 3", "gene_name": "Abcg3l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSSNDPTVIPMAERRYGDLPETNTSDPETLTEEAVLSFHNISYRETVQSGFPLRQQTHVMERLSSISGIMGPGLNAIMGPQDGSRSLLLDVLAARRDPCGLSGDILVNGKPQPANFKCTSGYVPQNDVIMHTVTVRDNLEFSAALRLPMTITRNEKRRRINEVLELLHLEKEQNTKPRSKELRKRTSIAVELVTEHPILFLDDPTTGLDLRTTTDIIAVLRRMSKKGRTVIFSINQPQYSIFRFFDSLTLVASGKLMFHGPAQDALEYFTSAGYQYESHNNPADFFLDVINGGLCDTEEDGHEADEHEDLYERLHQVTEKLANMYAQSPLHSDTRAKLDQLLGEQKQDRRSAMETTFVTPFWHQFGWITLRSFKNFKGFPWVTVIQAIIAVILAVFVGTIFRLLQNVCTEVKARAGLLFFLTGFECILSVSAGELFLLDRNHFLHEHTSGYYRVSSYFFGKLLAELIPRRLLPSMIFTLITYFIAGMKTGVKGFFVTIFTVMMLASSASSLSLSLGAGENTAALPTTLITIYFMFMLFFSGLSLFSINFLPQLSWIQYLSIPHYGFRALLHNEFLGQNFCPEHNTEEVSRCQNYVIRLQDTFWKTSRNQRLVIVLGCVCVCVCVCVCVCVCVSVCLCLSLCVSVYVSLCVKCPIREYVLQ", "length": 661 }, "evidence": [ { "id": "RGD:1561523", "url": "https://alliancegenome.org/gene/RGD:1561523#orthology", "database": "AGR" }, { "id": "HGNC:25395", "url": "https://alliancegenome.org/gene/HGNC:25395#orthology", "database": "AGR" }, { "id": "MGI:97072", "url": "https://alliancegenome.org/gene/MGI:97072#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120727-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120727-3#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GE08-1", "protein_name": "Guanylate binding protein 1", "gene_name": "Gbp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDMTLQIHMPGPVCLIENVKGQLRANQKALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKKTGFSLGSTVQAHTKGIWMWCVPHPNKANHMLVLLDTEGLGDVEKGDNQNDCWIFSLAILLSSTFVYNSMGAINQQAMDQLHYVTELTDRIRARSSPDQDDGVEDSAEFVSFFPDFVWTLRDMTLKMEVDGLQVTADEYLEISLKLKEGSSKEVEKYNLPRLCIRKFFPKKKCFVFYPPTEWKRLSQLETLQENEIDSEFLQQVAEFCLYVFKECKAKTLPGGIIVNGPRLETLVLTYLSAISSGDLPCMENAVLTLAQIENSAAVEKAITHYDQQMSQRVQLPTETLQELLDLHRTCEREAIEIFLRVSFKDEDHSFQMKLGSRLEERWNDFCKRNMEVSSNRCWALLQDIFRPLEESVKQGTYSKPGGYYLFVQETQRLKEKYQGQPKKGLQADEVLQKYLQSKEAITTAILQTDQSLTEKEKEIEVERKKAESAQAAAKLLEETQKKNEKLMEQKERSYQEHMKQLTEKMENDRIQLKAEQERILSLKLQEQKQLLQEGFREESRKLQEEMKNVEKRYKETMDHMKAESSKTKEEMQRKYEQMLEKDRNHQEHTLHMIEKMERDRAQLVAEQEKTMTLILQERELQLRNELAEERRKHEKEIQDIVAENRQIILKLESERAESAENTIKMLTELNELNLKTLGQKQKTLEDHLIQLTEQRDKDTASLMAEQGKIFDSKLQEQEENFNKKIRAQSQQHREEIWKIKKEGFSCSLM", "length": 780 }, "evidence": [ { "id": "RGD:1311877", "url": "https://alliancegenome.org/gene/RGD:1311877#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120727-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120727-3#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AB13A7Z1-1", "protein_name": "Uncharacterized protein LOC100322630", "gene_name": "si:dkeyp-30d6.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKPVCLINTDSDGKLYVQPAALQVLQQIQQPVVVVAVVGLYRTGKSYLMNHLAGKQTGFALGGTIESKTKGIWMWCVPHPTKTGTTLVLLDTEGLGDVEKGDSKHDTNIFCLAVLLSSTLVYNSRGTINNRAIEELQYVTELTECIKVKSSDEDVDDSTEFVKFFPSFIWSVRDFTLERKIDGKDATEDEYLEFALKLKPGTSKKITSFNLPRECIQKFFPTRTCFTFPFPTAPEKMSTLESLSPADLSTEFLEVTKRFCKFVFDKSEVKRLKDGHTVTGRVLGNLTKMYVNTISSGAVPCLENAVIAMAQIENVAATQEGLEVYQRGMEKVKCSFPLELEQVSSEHQRLSSKATQAFMARSFKDTDGKHLKVLEVG", "length": 378 }, "evidence": [ { "id": "RGD:1561523", "url": "https://alliancegenome.org/gene/RGD:1561523#orthology", "database": "AGR" }, { "id": "HGNC:25395", "url": "https://alliancegenome.org/gene/HGNC:25395#orthology", "database": "AGR" }, { "id": "MGI:97072", "url": "https://alliancegenome.org/gene/MGI:97072#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A4UUI3-1", "protein_name": "Guanylate-binding protein 4", "gene_name": "Gbp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTQPQMAPICLVENHNEQLSVNQEAIEILDKISQPVVVVAIVGWSHTGKSYLMNCLAGQNHVSGTLPTSQRFPSGLHRAVSDQGHLDVVHAPPHQARALVLLDTEGLGDVEKGDPKNDLWIFALSVLLSSTFVYNSMNTINHQALEQLHYVTELTELIRAKSSPNPHGIKNSTEFVSFFPDFVWTVRDFMLELKLNGEDITSDEYLENALKLIPGNNPRIQASNSARECIRRFFPNRKCFVFEWPTHDIELIKQLETISEDQLDPTFKESAMAFASYIFTYAKIKTLREGIKVTGNGLGTLVTTYVDAINSGAVPCLDDAVTTLAQRENSVAVQKAASHYSEQMAQRLSLPTDTIQELLDVHAACEKEAMAVFMEHSFKDENQQFLKKLVELLREKNGLFLLKNEEASDKYCQEELDRLSKDLMDNISTFSVPGGHRLYMDMREKIEHDYWQVPRKGVKASEVFQNFLQSQAIIESSILQADTALTAGQKAIAEKHTKKEAAEKEQDLLRQKQKEHQEYMEAQEKRNKENLEQLRRKLEQEREQLIKDHNMMLEKLTKEQKTFREEGYKTQAEELRREIHQLGHNIKEMKQNGDSLVESILRSWFSFISPPSESEKAISSVLSLLRKKDRL", "length": 631 }, "evidence": [ { "id": "RGD:1561523", "url": "https://alliancegenome.org/gene/RGD:1561523#orthology", "database": "AGR" }, { "id": "HGNC:25395", "url": "https://alliancegenome.org/gene/HGNC:25395#orthology", "database": "AGR" }, { "id": "MGI:97072", "url": "https://alliancegenome.org/gene/MGI:97072#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120727-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120727-3#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZV82-1", "protein_name": "Guanylate binding protein 7", "gene_name": "Gbp7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASASSMEAPICLVENENEELRVNPKAINILERITQPVVVVAIVGLYRTGKSYLMNRLAGQNHGFNLGTTVRSETKGIWMWCVPHPCKPKFTLVLLDTEGLGDVEKCDPKNDSWIFALAVLLSSTFVYNSMSTINHQALEQLHYVTELTELIRTKSTPRSEEIDDSDEFVGFFPDFIWVVRDFVLELKLDGRVITADEYLENALKLIPGRSLKAQNSNLPRECIRHFFPRRKCFVFDRPIKEKELLVHVEEMPEDELDHNFREQSNVFCSYIFSNAKAKTLKEGIMVNGNRLATLVTTYVDAINSGAVPCLENAVTTLAQRENSAAVQKAAEHYSEQMAQRLRLPTDTLQELLDVHSACEKEAIAVFMEHSFKDENQEFQKNLVVTIVEKREDFSRQNEAASLSHCQAELDKLSESLRESISCGAFSVPGGHSLYLEARKKVEQDYEQVPRKGVKANHVLQSFLQSQIVIENSILQSDKALTVNQKAMEVERAQKEAAEKEQELLRQKQKELQQVMESQERSYKENIVQLHEKMETERKNILEKQEEMLAHKLKVQEEMLNEGFKRKYEAMDSEISQLQKQIQQNKEQNSSLAAQIFDGFGNVLMSVLPGTGKLFGLGLKILSRKMK", "length": 627 }, "evidence": [ { "id": "RGD:1583235", "url": "https://alliancegenome.org/gene/RGD:1583235#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120727-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120727-3#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P32455-1", "protein_name": "Guanylate-binding protein 1", "gene_name": "GBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAGKKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRKACTIS", "length": 592 }, "evidence": [ { "id": "RGD:1311877", "url": "https://alliancegenome.org/gene/RGD:1311877#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1MT80-1", "protein_name": "Guanylate-binding protein 4", "gene_name": "gbp4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKPVCLIDTGSDGKLCVQQAALQVLQQIQQPVVVVAVVGLYRTGKSFLMNRLAGKRTGFALSSNIKPKTEGIWMWCMPHPTKAGTTLVLLDTEGLEDVEKGDSKRDTYIFSLAVLLSSTLVYNSRGVIDNKAMEELQYVTELIEHIKVTPDEDADDCTAFAKFFPHFIWCLRDFTLELKLDGKDLTEDEYLEFALKLRPGTSKKVMMYNLPRECIRKFFPCRTCFTFPSPTTPEKRSILESLSPAELDPEFLEVTKRFCKFVFDRSEVKQLKGGHTVTGRVLGNLTKMYVDTISSGAVFCLENAVIAMAQIENEAATQEGLEVYQRGMEKLKSSFPLELEQVSSEHQRLSSMATQAFMARSFKDTDGKHLKALEGEMGKLFDAYRSQNKQVGLETHCDLLLYMRCKDPLILHVYFFPVNDARSKEKVEQNERSSLPISHPRPDRPFQVKTPHVLEVPGASVYPEEGISFRTDVEPNFFKVRKLQVDDVQMNLVRQKDKMSVWTTTIWKEEFVHLQQVRDERKLNSEIEKNDFFNAHRVAFIERVTNVKSIADKLHGQRIIHKELYSEITQTNVTRQQIMRKICDSVDSSGRIAKCKFIDILQEEERCLLEDLKQSES", "length": 618 }, "evidence": [ { "id": "RGD:1561523", "url": "https://alliancegenome.org/gene/RGD:1561523#orthology", "database": "AGR" }, { "id": "HGNC:25395", "url": "https://alliancegenome.org/gene/HGNC:25395#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZN66-1", "protein_name": "Guanylate-binding protein 6", "gene_name": "GBP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVVVAIVGLYRTGKSYLMNHLAGQNHGFPLGSTVQSETKGIWMWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSSPRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITEDEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFVFDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFTHARTKTLREGITVTGNRLGTLAVTYVEAINSGAVPCLENAVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQELLDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKKGDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPGGHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMVIEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQKLQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIMMLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTKNDDTPWIARTLDNLADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF", "length": 633 }, "evidence": [ { "id": "RGD:1561523", "url": "https://alliancegenome.org/gene/RGD:1561523#orthology", "database": "AGR" }, { "id": "HGNC:25395", "url": "https://alliancegenome.org/gene/HGNC:25395#orthology", "database": "AGR" }, { "id": "MGI:97072", "url": "https://alliancegenome.org/gene/MGI:97072#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120727-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120727-3#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N8V2-1", "protein_name": "Guanylate-binding protein 7", "gene_name": "GBP7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASEIHMPGPVCLTENTKGHLVVNSEALEILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKNKGFPLGCTVKSETKGIWMWCVPHPSKPNHTLILLDTEGLGDMEKSDPKSDSWIFALAVLLSSSFVYNSMGTINHQALEQLHYVTELTELIRAKSCPRPDEVEDSSEFVSFFPDFIWTVRDFTLELKLDGHPITEDEYLENALKLISGKNPQIQNSNKPREWIRHFFPKQKCFVFDRPINDKKLLLHVEEVREDQLDSNFQMQSENFCSYIFTHAKTKTLREGILVTGNRLGMLVETYLDAINSGATPCLENAMAVLAQCENSAAVQRAANHYSQQMAQQVRFPTDTLQELLDVHAVCEREAIAVFMEYSFKDKSQEFQKKLVDTMEKKKEDFVLQNEEASAKYCQAELKRLSELLTESISRGTFFVPGGHNIYLEAKKKIEQDYTLVPRKGVKADEVLQSFLQSQVVIEESILQSDKALTAGEKAIAAKQAKKEAAEKEQELLRQKQKEQQQMMEAQERSFQENIAQLKKKMERERENYMRELRKMLSHKMKVLEELLTEGFKEIFESLNEEINRLKEQIEAAENEEPSVFSQILDVAGSIFIAALPGAAKLVDLGMKILSSLCNRLRNPGKKIIS", "length": 638 }, "evidence": [ { "id": "RGD:1583235", "url": "https://alliancegenome.org/gene/RGD:1583235#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91Z40-1", "protein_name": "Guanylate-binding protein 7", "gene_name": "Gbp7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGPNMEAPVCLVENENEELRVNSKAINILERITQPVVVVAIVGLYRTGKSYLMNRLAGQNHGFNLGTTVRSETKGIWMWCVPHPSKPKFTLVLLDTEGLGDVEKGDPKNDSWIFALAVLLSSTFVYNSMSTINHQALEQLHYVTELTERIRAKSTSRSEEVDDSDEFVSFFPDFIWTVRDFVLELKLEGRVITADEYLENALKLIPGMSIKAQKANLPRECIRHFFPRRKCFVFDRPTKDKELLVHVEEMPEDQLDHSFQVQSKEFCSYIFSNSKAKTLKEGIVVNGNRLATLVTTYVDAINSGDVPCLENAVTTLAQRENSIAVQKAADHYSEQMAQRMRLPTDTLQELLTVHTACEKEAIAVFMEHSFKDENQQFQKNLVVTIEEKKEDFLRQNEAASLSHCQAELDKLSESLRESISRGVFSVPGGHRLYLEARKKVEQDYERVPRKGVKANHVLQSFLQSQISIEDSIMQSDKALTDGQKAMEAERAQKEAAEKEQELLRQKQKELQQVMEAQERSYKENVAQLHEKMETERKNILREQEVKLEHKLKIQKDMLNEGFKRKCEAMDLEISQLQKEIQLNKEKNSSLGAKILDGFGDVLISVVPGSGKYFGLGLKILSSQMNQTQNSDKVRKL", "length": 638 }, "evidence": [ { "id": "RGD:1583235", "url": "https://alliancegenome.org/gene/RGD:1583235#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0R5-1", "protein_name": "Guanylate-binding protein 3", "gene_name": "GBP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPEIHMTGPMCLIENTNGELVANPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKNKGFSLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDVKKGDNQNDSWIFTLAVLLSSTLVYNSMGTINQQAMDQLYYVTELTHRIRSKSSPDENENEDSADFVSFFPDFVWTLRDFSLDLEADGQPLTPDEYLEYSLKLTQGTSQKDKNFNLPRLCIRKFFPKKKCFVFDLPIHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIKVNGPRLESLVLTYINAISRGDLPCMENAVLALAQIENSAAVQKAIAHYDQQMGQKVQLPAETLQELLDLHRVSEREATEVYMKNSFKDVDHLFQKKLAAQLDKKRDDFCKQNQEASSDRCSALLQVIFSPLEEEVKAGIYSKPGGYCLFIQKLQDLEKKYYEEPRKGIQAEEILQTYLKSKESVTDAILQTDQILTEKEKEIEVECVKAESAQASAKMVEEMQIKYQQMMEEKEKSYQEHVKQLTEKMERERAQLLEEQEKTLTSKLQEQARVLKERCQGESTQLQNEIQKLQKTLKKKTKRYMSHKLKI", "length": 595 }, "evidence": [ { "id": "RGD:1311877", "url": "https://alliancegenome.org/gene/RGD:1311877#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9Q7" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9Q7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9Q7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9Q7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P9Q7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9Q7" }, { "id": "PS51715", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51715" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GB1/RHD3-type G", "eco_id": "ECO_0000259", "start_pos": 30, "end_pos": 269, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9P9V2-1", "uniprot_ac": "A0A8M9P9V2", "uniprot_id": "A0A8M9P9V2_DANRE", "mass": { "chemical_mass": 35663.0, "monoisotopic_mass": 35663.0 }, "refseq": { "ac": "NP_001096105", "name": "uncharacterized protein LOC100124608", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096105" }, "gene_names": [ { "name": "si:dkey-10o6.2", "type": "recommended", "evidence": [ { "id": "A0A8M9P9V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9V2" } ] }, { "name": "si:dkey-10o6.2", "type": "synonym", "evidence": [ { "id": "NP_001096105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096105" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9P9V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9V2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100124608", "type": "synonym", "evidence": [ { "id": "NP_001096105", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096105" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC150233.1, SRR32588721.3761516.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On or before Jul 17, 2025 this sequence version replaced XP_021323238.1, NP_001096105.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001096105", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096105" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9V2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-10o6.2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9V2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-284", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-284", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P9V2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9P9V2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100124608", "url": "https://www.ncbi.nlm.nih.gov/gene/100124608", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027443", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027443", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P9V2", "url": "https://www.orthodb.org/?gene=A0A8M9P9V2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47990", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47990", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001096105", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001096105", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9V2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P9V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9V2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-284", "url": "https://zfin.org/ZDB-GENE-070705-284", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEIPIVDFNVFELGKTNVSADELDDLSKEVKRAFTDVGFVYLKNTGISQEEVDNVMAVSKKFFSLPEDVKKSFSRGSFPCNENHGWVSVETESLNPRRPGDLKEAFNTSTLSADIKWPSEGVADFRDVQVSFFLRCKELSLRVLRLMALGLGLESEVFLDAHKLIGSDVNRTTLRSLFYPPVKSTSVKENQLRCGEHSDYGSITLVFQSREGGLQVLSRAGEYISAPSICGTVLVNIADMMQRWTSDIYVSAVHRVLLPPAGDSSTRQSLAFFVQPDDDAMISCCDGSDKYPPVRSLDYLLSRFSESYITKNTSDMSLIL", "length": 320, "header": "tr|A0A8M9P9V2-1|A0A8M9P9V2_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-10o6.2 PE=3 SV=1 CANONICAL=A0A8M9P9V2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P9V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9V2/entry#A0A8M9P9V2-1", "sequence": { "sequence": "MEIPIVDFNVFELGKTNVSADELDDLSKEVKRAFTDVGFVYLKNTGISQEEVDNVMAVSKKFFSLPEDVKKSFSRGSFPCNENHGWVSVETESLNPRRPGDLKEAFNTSTLSADIKWPSEGVADFRDVQVSFFLRCKELSLRVLRLMALGLGLESEVFLDAHKLIGSDVNRTTLRSLFYPPVKSTSVKENQLRCGEHSDYGSITLVFQSREGGLQVLSRAGEYISAPSICGTVLVNIADMMQRWTSDIYVSAVHRVLLPPAGDSSTRQSLAFFVQPDDDAMISCCDGSDKYPPVRSLDYLLSRFSESYITKNTSDMSLIL", "length": 320, "header": "tr|A0A8M9P9V2-1|A0A8M9P9V2_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-10o6.2 PE=3 SV=1 CANONICAL=A0A8M9P9V2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q86B82-1", "protein_name": "Fe2OG dioxygenase domain-containing protein", "gene_name": "CG5340", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKSETETLLLQNAVPIIDLENTIEDVATNLREALSEKGYALLINHGISNEKIKKAWKYFDGFVDLTDEVKLAFERSKAPDGENHGYVSPGMERFDGRTPELRHAYNICKLQDKFLPEQQLPGFSRHINSLVDDFNELGRFILKALAISLDAPPSFFTDKHSFMLSDDRFNLTTLRMLFYPPVEDQDHGRSFIRCGAHADYCTFTLLAQDSEGGLEVKLRGSDKWERVGHLPGALFINCGETMAIWTDQFYHALQHRVVIPDQVDIRHRGRHSIAYFCHPDNSALINPKDLNITTKQTTSDVIQNAYDITMALAKGAFAHHYS", "length": 322 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070705-284", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-284#orthology", "database": "AGR" }, { "id": "FB:FBgn0053093", "url": "https://alliancegenome.org/gene/FB:FBgn0053093#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86B83-1", "protein_name": "Fe2OG dioxygenase domain-containing protein", "gene_name": "CG5340", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MINSKIREDKLETLVSRSSVPIIDLAHCGKSLVHRVGQQLHKAFTEKGIAFLVNHGIAEDKIKAVWDQFDNFLDLPAEVQDRYRRKDGVNYGYVSPGMERFDGSTPELRHAYNVCKLDGQNIPREALPEFAEGITTLCTDLKAMSLYIMKAMEVALEIPPSFFIDKHSQMLEGDDLNMTTLRMLYYPAIVDDEPGQSEGAIRCGAHVDYGTFTLLAQDSEGGLEVQLPGSEKWERVGHLPGAILINGGELLSIWTKQRYHALPHRVVIPEQELIRTRGRHSIAYFCHPNNSILISPNDLLSEGEAKSEDKVYSAYELIQKKFNDTYGQRSQ", "length": 331 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070705-284", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-284#orthology", "database": "AGR" }, { "id": "FB:FBgn0053099", "url": "https://alliancegenome.org/gene/FB:FBgn0053099#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VCZ2-1", "protein_name": "Fe2OG dioxygenase domain-containing protein", "gene_name": "Dmel\\CG5346", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIKTKSSDDKLDTLLSRSVVPIIDLAHCGIEEVPVKSVVNRVGHQLKKALSEKGMALLVNHGISDEKLKTAWDHLDDFVNLPPDIRQHYIRADGDKHGYVSRGQQQRFDGKSPELRHAFNISTLNAQNLPEEPLPGFADHISTLATDFKALASFILQALAVSLDIPHTFFLEKHSHMLSGDHDNMSSLRMLYYPPIVDDEPGQNDVIKGRCQYSYQRCLSNQPDFRPEHNPRDEDDLNEVDGPNGQLFEHKLGNGAVIQCPPHVDYGTFTLLSQDSEGGLEVRLPGSEKWNRVGHLPGSILVNCGEILNIWTQGRYPALQHRVIIPEQETIRARGRHSIAFFCHPDNITTISPTDLPNPDAVQDKACLKQRKKSFKAAKERVYNAYQLIQKKFRDTYSSNNHS", "length": 403 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070705-284", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-284#orthology", "database": "AGR" }, { "id": "FB:FBgn0038981", "url": "https://alliancegenome.org/gene/FB:FBgn0038981#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9V2" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P9V2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9V2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9P9V2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P9V2" }, { "id": "PS51471", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51471" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fe2OG dioxygenase", "eco_id": "ECO_0000259", "start_pos": 170, "end_pos": 276, "start_aa": "Asn", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 17, "end_pos": 19 }, { "start_pos": 312, "end_pos": 314 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PA98-1", "uniprot_ac": "A0A8M9PA98", "uniprot_id": "A0A8M9PA98_DANRE", "mass": { "chemical_mass": 52947.0, "monoisotopic_mass": 52947.0 }, "refseq": { "ac": "XP_021323413", "name": "CUB and zona pellucida-like domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323413" }, "gene_names": [ { "name": "LOC110438081", "type": "recommended", "evidence": [ { "id": "A0A8M9PA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PA98" } ] }, { "name": "LOC110438081", "type": "synonym", "evidence": [ { "id": "XP_021323413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323413" } ] } ], "protein_names": [ { "name": "CUB and zona pellucida-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_021323413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323413" }, { "id": "A0A8M9PA98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PA98/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323413.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323413", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323413" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PA98", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PA98" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438081", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PA98", "locus": {} } ], "crossref": [ { "id": "A0A8M9PA98", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PA98", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438081", "url": "https://www.ncbi.nlm.nih.gov/gene/110438081", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048290", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048290", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110438081", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438081", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PA98", "url": "https://www.orthodb.org/?gene=A0A8M9PA98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002", "url": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PAH3-1", "uniprot_ac": "A0A8M9PAH3", "uniprot_id": "A0A8M9PAH3_DANRE", "mass": { "chemical_mass": 94567.0, "monoisotopic_mass": 94567.0 }, "refseq": { "ac": "XP_021323513", "name": "extracellular calcium-sensing receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323513" }, "gene_names": [ { "name": "olfcd1", "type": "recommended", "evidence": [ { "id": "A0A8M9PAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAH3" } ] }, { "name": "olfcd1", "type": "synonym", "evidence": [ { "id": "XP_021323513", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323513" } ] } ], "protein_names": [ { "name": "Extracellular calcium-sensing receptor", "type": "synonym", "evidence": [ { "id": "A0A8M9PAH3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAH3/entry#names_and_taxonomy" } ] }, { "name": "extracellular calcium-sensing receptor", "type": "synonym", "evidence": [ { "id": "XP_021323513", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323513" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323513", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323513" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAH3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "olfcd1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAH3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd06364", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06364", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "795062", "url": "https://www.ncbi.nlm.nih.gov/gene/795062", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:795062", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795062", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PAH3", "url": "https://www.orthodb.org/?gene=A0A8M9PAH3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061:SF528", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061:SF528", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323513", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323513", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAH3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PAH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAH3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100721-9", "url": "https://zfin.org/ZDB-GENE-100721-9", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTKKSELLLLMVLVTHGICVPNLAQVCRLLGQPALPLLSEERNINIGAIFSLHKSALLKSHNFTSKPKQTTCGGLNLREFKFVQTLIFAIEEINNSSLLPGASLGYKIYDSCGSVAQAIFSGMALMNGYEETLSDTSCSTPPAVHAIVGESNSSPTIGLASVVGPFSLPLVSHFATCSCLSNRKRFRTFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGIATFEEAAKQEGICIEYSEAVFKTDPEVQFLKTIEVIKKATTKVVVAFMAFGDFVLLLKVMAQQNITGIQWIGSESWITSRNLAETKEYHFLSGAVGFAIANSKPVGLREFLMNVHPDKELNNELLKEFWETVFLCSFRNSSSGGCTGSEKLSELQNEYTDFSELRIENKVYTAVYAVAHSLHNVLKGFKFFTNSSKKQLPTPQKVLEYLRDVNFTVNTNENIFFDASGDPVARYDLVNWQPTKDGSLQFKLVGIYDSSLPSEQRLQINQESMLWAGNSGQLPVSVCSESCPPGTRKAVQKGRPICCYDCIPCAEGEISNYTDSSDCFPCGLEYWSNESKDRCVLKVIEFLSYTEIMGVGLCIFSFIGVLLTATVSFLFYFYKETPIVRANNSELSFLLLFSLTLCFLCSLTFIGRPTDWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLIQVIICVLWLTMSPPFPFLNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFFARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSAPGKYTVAVQLFAILASSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKS", "length": 849, "header": "tr|A0A8M9PAH3-1|A0A8M9PAH3_DANRE Isoform 1 of Extracellular calcium-sensing receptor OS=Danio rerio OX=7955 GN=olfcd1 PE=3 SV=1 CANONICAL=A0A8M9PAH3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PAH3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAH3/entry#A0A8M9PAH3-1", "sequence": { "sequence": "MTKKSELLLLMVLVTHGICVPNLAQVCRLLGQPALPLLSEERNINIGAIFSLHKSALLKSHNFTSKPKQTTCGGLNLREFKFVQTLIFAIEEINNSSLLPGASLGYKIYDSCGSVAQAIFSGMALMNGYEETLSDTSCSTPPAVHAIVGESNSSPTIGLASVVGPFSLPLVSHFATCSCLSNRKRFRTFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGIATFEEAAKQEGICIEYSEAVFKTDPEVQFLKTIEVIKKATTKVVVAFMAFGDFVLLLKVMAQQNITGIQWIGSESWITSRNLAETKEYHFLSGAVGFAIANSKPVGLREFLMNVHPDKELNNELLKEFWETVFLCSFRNSSSGGCTGSEKLSELQNEYTDFSELRIENKVYTAVYAVAHSLHNVLKGFKFFTNSSKKQLPTPQKVLEYLRDVNFTVNTNENIFFDASGDPVARYDLVNWQPTKDGSLQFKLVGIYDSSLPSEQRLQINQESMLWAGNSGQLPVSVCSESCPPGTRKAVQKGRPICCYDCIPCAEGEISNYTDSSDCFPCGLEYWSNESKDRCVLKVIEFLSYTEIMGVGLCIFSFIGVLLTATVSFLFYFYKETPIVRANNSELSFLLLFSLTLCFLCSLTFIGRPTDWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLIQVIICVLWLTMSPPFPFLNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFFARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSAPGKYTVAVQLFAILASSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKS", "length": 849, "header": "tr|A0A8M9PAH3-1|A0A8M9PAH3_DANRE Isoform 1 of Extracellular calcium-sensing receptor OS=Danio rerio OX=7955 GN=olfcd1 PE=3 SV=1 CANONICAL=A0A8M9PAH3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:795062", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795062", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JYG8-1", "protein_name": "Vomeronasal 2 receptor, 12", "gene_name": "Vom2r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTLILSFLLLNIPLQVTGFIYPTCSWRIKENKDKSGNERIGCFFLIQAVQKPVEKEYFSHFFNTQKHTEIHKYSLVLAFSMIEVNRNPDLLPNMSLVFSFREIICGWQPELSIFIEVNLDDYGVLPNYTCKDDSLCGVVLTGLNWAPTLLLYTILNNFKSQQFPHLTYGHYHPVPSDHENFPYLYQMASDDTSLALALVSFIIHFSWNWIGLAFSDNDQGTHFLSYLKRGMEKNAVCLAFVSMIPVDMHLYMSRAEVYYSQILTSSANVVIIYGDTGSTLAVSFRMWESLGLQRLWITTTQLDVTPSMKENIYGLFAFGHHHGVISGFKNFVQTLNPVTYSNDNLAKLEWMHFNCEVSASKWKTLKNFSSNHSLEWLMENTFEMTFSEGSYNIYNAVYTVAHVLHKMTFQKFHNLPNAKGKVQNYVCNKLGAPLRKIHFTNPVGDRINMNREDKLQEEYDIFYIWNFPQGLAFKVKIGLFSPYFINGQQLHLSGDMIEWARGSTQMPTSVCSADCGPGFRKFRKKEMSACCFDCSPCPENEISNETNMEMCVLCPEDKYANTGQNDCIPKALIFLSYEDHLGMALSLMALGFSAFTAVVLGIFVKHHSTPIVKANNRTLTYILLLSLIFCFLCPLLFIGHPDSVTCILQQITFGVLFTVAISTVLAKTITVILAFKVTAPQRMMKYFLLSGVSMYIIPICTLIQVIVCAVCLGVSPPSVDIDAQSEHGHIIVVCNNGSVTCFYSVLGYLACLTFVSFTLAFLSRNLPGAFNEAKSITFSMLVVCSVWVTFLPVYHSTKGKIMVAVEIISILASSSGMLVCIFIPKCYIILFRPEKNSLKMIREKSPSHTHIS", "length": 853 }, "evidence": [ { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JZT8-1", "protein_name": "Vomeronasal 2 receptor, 13", "gene_name": "Vom2r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTLILSFLFLNIPFQVTGFIYPTCSWRIKENKDKSGNERIGCFFLIQAVQKPVEKEYFSHFFNTQKHTEIHKYSLVLAFSMIEVNRNPDLLPNMSLVFSFREIICGWQPELSIFIEVNLDDYGVLPNYTCKDESLCGVALTGVNWAPTLLLYTILNNFKSQQFPHLTYGHFHPVLSDHENFPYLYQMASDDTSLALALVSFIIHFRWNWIGLAISDNDQGTQFLSYLKRGMEKNAICLAFVSMIPVNMHLYMSRAEVYYSQIMTSSANVVIIYGDTGSTLAVSFRMWESLGLQRLWITTTQLDVTPSMKDNVYGLFAFGHHHGVISGFKNFVQTLNPVTYSNENLAKLEWMHFNCEVSASKWKTLKNFSSNHSLEWLMEHTFEMTFSEGSYNIYNAVYTVAHVLHEMTFQKFHNLPNAKGKVENYVCNKLGAPLRKIHFTNPVGDRINMNREDKLQEEYDIFYIWNFPQGLAFKVKIGLFSPYFINGQQLHLSGDMIEWARGSTQMPTSVCSADCGPGFRKFRKKEMSACCFDCSPCPENEISNETNMEMCVLCPEDKYANTGQNDCIPKALIFLSYEDHLGMALSLMALGFSAFTAVVLGIFVKHHSTPIVKANNRTLTYILLLSLIFCFLCPLLFIGHPDSVTCILQQITFGVLFTVAISTVLAKTITVILAFKVTAPQRMMKYFLLSGVSMYIIPICTLIQVIVCAVCLGVSPPSVDIDAQSEHGHIIVVCNNGSVTCFYSVLGYLACLTFVSFTLAFLSRNLPGAFNEAKSITFSMLVVCSVWVTFLPVYHSTKGKIMVAVEIISILASSSGMLVCIFIPKCYIILFRPEKNSLKMIREKSPSHTHIS", "length": 853 }, "evidence": [ { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KAL5-1", "protein_name": "Vomeronasal 2 receptor 19 like 1", "gene_name": "Vom2r19l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTMIFLFLLLNIPLLMVDFIHPRCFWRMKQNEDKDGNPGTGCTFFLQSVHWPVEKEYYSDIFNIQMHNENHKYALALAFAIYEINGNPDLLPNMSLIFEFTRDVCDWESQLNSVIQSSLKNHNILPNYICKEFTKCPMALTGLNWTTTLKLHTILNNFISQQFLQVTYGPFHPVLSDNEKFPYLYQMASDDKSLALALVSFIIHFGWNWVGLAISNNDQGIQFLSYLRREMEKGTVCFAFVNMIPVNMHLYMSRAEMYYNQIMTSSTNVVILYGDTDSTLAVSFRMWESLGIEKIWVTNSWWAATLSKKDHTFDNLYGTYAFGQHHGEISGFKNFVQTLNPAKYSDEHLVKLEWMYFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFTGGSYDIYNAVYSFAHALHEMTFQIFDNLPKDNGREHNYSCKKLCSFLRKTSFTNPVGDRVNMNQRHKQKEEYDIFYIWNFPQGLGIKVKIGMFSPYFPNGQQLHLSEDVLEWAKGSAQMPTSACSADCGPGFRKSWKDGMATCCFHCKPCPENEISNETNVDVCARCPDDQYANIEQNRCIPKAVVFLSYEEPLGMALSLISLGFSVFTIVLLGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSAICILQQITFGVVFTVSVSTVLAKTITVILAFKVTASQRMMKYFLVSRVPNYIIPTFTLFQVILCAVWLGASPPSIDIDAKSEHGHIIIACHKGSVTTFYCVLGYLGTLASGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKIMVAVEIFSTLASSAGMLGCIFVPKCYTVLFRQDQNSLVMIRMKSSSHAHIS", "length": 857 }, "evidence": [ { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0R4IS27-1", "protein_name": "Olfactory receptor CG6 precursor", "gene_name": "olfcg6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFLFYTILLFHLLHTKVENSLCRIMGDSNYPLFSKNGDVSIGGIFAIHRKETLPSFEFMQKPQPLSCSSVNLRDFRLAQTMIFAVEEINRSKSLLPNVSIGYKIYDTCGSRLSTMTAIMGLMNGQDFSTEDRCNGQSRLHAIIGESESSATIVLSRTTGPFRIPVISHSSSCECLSNKKDYPSFFRTISSDYHMSRALVYIVKHLDWSWVGAVNSDNDYGNNGMAIFLKAAHEEGICVEYSVKFYRTEPEKLKKVVDTINKGTAKVIVAFVSFVEMGLLIDQLSIQNITGIQMIGVEPWITANTYITSNSFRAMGGSLGFATKYIYIEGFAEYVMTPFWNTAFPCSESDRNHSHYELICSRYEDLLALKNDNKDVNEHRYSSNVYKAVYAVAHSLHGLLNCKEQEGCEKGLTIQPQQVVKALKNINFTIKSGDSVWFDNTGSVVALYEVVNWQKDSDGSFQFKSVGFYDAMMPPYKNLRLNTKNIVWAGGQLEKPRSVCSESCAPGTRKAAQKGRPVCCYDCIPCAEGEISNETDSINCKQCPGEYWSNTERNRCVIKAVEFLSFSEVMGIVLVIFSLFGAGLTVLVAVLFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTKWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPVQQRLSVFAFTLIQVLICVLWLTISPPFPYKNMKYYKEKIILECNLGNTIGFWAVLGYIGLLAALCFLLAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSFGLLVSIFAPKCFIILLKPEQNTKQHVMGKTTCSL", "length": 837 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A140T8U3-1", "protein_name": "Vomeronasal 2, receptor 130", "gene_name": "Vmn2r130", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLILLFLLLNIPLIVADFIYSRCFWRIKQNKDKDGNLGSGCALFIQAVQWPVEKEYFSPILNTQTYTENYKYILVFMFSINEVNRNSDLLPNMSLIFTFSALSCNESQLKSFIHLSLQDHDYFPNYICNDYICGVALVGLKWETTLTLYTILNNFMSHQFLFLNYGPFHPAMSDHEEFPYIYQMASEDTSLALAMVSFIIHFSWNWVGLAISDNDEGIQFLSHLRREMEKNTVCFAFVSMIPVNMHLYMTRTEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLDIKRIWVTTSQWDIITSKKDFTFNNLYGTFAFGHHHGEISGFKNFVQTLDLLKFSDEYLVKLEWMYFNCEDSAPKCKTLKNCSSNHPLEWLMVRTFDMAFTEGSYAIYNAVYAVAHALHELTFQKFDNLRPDNVKGQKYACNKLGSFLRKIHFTNPVGDRVNMNQRNKLQENYDIFYVWNFPQGLRLKVKIGIFSPYFINGQQLHLSEDMLEWARGSTQMLTSVCSADCGPGFRKFRRNGMPACCFDCRPCPENEISNETNVELCVPCPEDQYANTEQNNCIQRAVIFLTYKDPLGMALSLMALCFSAFTAVVLLVFVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCVLQQVTFGVAFTVAVPTVLAKTITIVLAFRVTAPQRMMKYFLVSGASIYIIPICTLIQVIVCAVWLGAAPPSVDIDARSEHGHIIIVCNKGSVSAFYCVLGYLACLAFGSFTLAFLSRNLPSTFNEAKSITFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSTLASGAGMLICIFVPKCYIILFMPDRNSLQMIRKKSSSHAHLS", "length": 855 }, "evidence": [ { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W422-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r54", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSASMWGYRVTQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQKEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSYQSLGKIEETVQKMQKCTAKVVLVFLSNLNFQLILRGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVSSLNAEETVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFVLALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQICLSPGTSTFVVLIASLIQVVLCGVWLATSPPFPDKDMISEPQHIVIQCQEGSGATFFCVLGYLGFLAGGTFSVAFLARGLPDIFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLKQGYCAQQEKQGEMLQRRYKFSGESPEPNI", "length": 878 }, "evidence": [ { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W4A7-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r53", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCTLLSVLFGCLSGSALSGPRVWIIPRQSPRFDRPGDVIVGGSFSIFHFSDGTLSNFTAPPPVLKTSSASMWSYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTCSHAVTQLVIHFQWSWVIILAHDDDFGQQASSLATQMLTPAGVCIEYHLHVPSHQSFGKIEETVQKMQKCTARVVLVFLSNSNFQLILHGLLAVPVSGQVWVSMDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSRIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHNLRNVYFKTSDGNKIMFDANGDLVTQFDIFQGKKTPAGVFHLVHVGLIDPQASSGNKMMVQLKQDLQVSSLNAEITVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTIFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQVCLSSGASTSVVLIASLIQVVLCGIWLITSPPFPDRDMISEPRHTVIQCHEGSGANFFCVLGFLGFLAGGTFSVAFLARGLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHQVQHNRQCEMLQRRCVSSGESLGSSL", "length": 878 }, "evidence": [ { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2WBA1-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r56", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLSCHWLSDPLAGMWLCTLLPVLFGCPSGSALSGARAWLLPRQSPHFDRPGDVIVGGSFSIFRFSNGTLSNFTAPPAGLQTSSVSMWGYRVAQSFVFAIEEINRSTHLLPNLTLGFSIRNSGDSAHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTSSHAVTQLIIHFQWSWVIILAHDDDFGQQASSLASQVLTPAGVCIEFYLYVPSHQSLGKIEETVRKMQKCTARVVLVFLSNYNFQLILYGLLAVPVSGQVWVSKDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCMWPYQNITVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHDMISYEHQDGKGTNSQDFQPWQLLHVLRKVHFKTPDGSEIMFDANGDLVTKFDIFQGQKTPDGVFHLVCVGLIDPQASSGNKMMVQKKMLKYQMKHAQVPTSVCSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCCIILLKPEKNTSSWLRQGHHV", "length": 865 }, "evidence": [ { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2WCY4-1", "protein_name": "Vomeronasal 2, receptor 16", "gene_name": "Vmn2r16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLHAFTISFSLLKFSLILYSLTEPNCFWRIQSNEDNDGDLRSDCGFVLFTYEGPIEEKFYNNVIHFSGTMNNLDLIWNAQQSRNGGHTCDPDLEDGRSSLLIWMLKNSGHEKHRIPARRYEFLLVMYFATDEINRNPYLLPNMSLIFSLIVGMCEDTLGYIEEKYSPQKNRLNFINYNCGIPQTCNIQITGPSWTTSLKLAINSRRPKVFFGPFNPNLSDHDQFPYVHQVSTKDTHLSHAMVSLMLHFKWTWIGLVISDDEQGIQFLSGLREEMQTYAICLAFVNMIPETMQIYMTRADIYDKQIIESTAKVVIIYGEMNSTLEVSFRRWGYLGARRIWITTSQWDVITNEKDFSLDFFHGTITFAHHNGRIAKFNNFLQTMNTSKYPIDVTQTMQDWNYFNCSIFKNSVRKTGQFIFNNTLEWTTQHKIDMVLSEEGHNLYNAVYAVAHTYHELILQQVESQKMPKLKGVFSDCHQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFNIWNFPQGLGLKVKIGSYFPCFPQSQQLCISENMEWATGGALVPTSMCSVTCAAGFRKIHQKHTADCCFDCVLCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGSMTMCFSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLILCFLCSLFFIGQPNHATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTTPGRRMRGMLASGTPNLVIPICSLVQLVLCGIWLVTSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFVPKCFVILVRPDSNFLQKYKDKLFY", "length": 897 }, "evidence": [ { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3Q4EIC8-1", "protein_name": "Vomeronasal 2, receptor 129", "gene_name": "Vmn2r129", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLCAFTISLLFLKFSLILCCWSEPSCFWRIKNSDDNDGDLQRECHFYLGAADTPVEDNFYSSLLKFRIAASEYEFLLVMFFAIDEINRNPYLLPNITLMFSFIGGNCQDLLRVMDQAYTQINGHMNFVNYFCYLDDSCAIGLTGPSWKTSLKLAMHSSMPLVFFGPFNPNLRDHDRLPHVHQVAPKDTHLSHGMVSLMFHFRWTWIGMVISDDDQGIQFLSDLREESQRHGICLAFVNMIPENMQIYMTRATIYDQQIMTSSAKVVIIYGEMNSTLEVSFRRWEELGARRIWITTSQWDVITNKKDFTLNLFHGTITFAHHRVEIPKLNKFMQTMNTAKYPVDISHTILEWNYFNCSISKNSIRMHHITFNNTLEWTSLHNYDMAMSDEGYSLYNAVYAVAHTYHEYIFQQVESQKKAKPKRYFTACQQVSSLMKTRVFMNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYLPCFPQRQKLHISDDLEWAKGGTSPQVPSSVCSVACTAGFRKIYQKETADCCFDCVQCPENEISNETDMEQCVRCPDDKYANIEQTHCLSRAVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKHNDTPIVKANNRILSYILLISLVFCFLCSLLFIGPPDQVTCILQQTTFGVFFTVSVSTVLAKTITVVMAFKLTTPGRRMRGMMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKIVILCNKGSVIAFHVVLGYLGSLALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSTRGRVMVVVEVFSILASSAGLLMCIFVPKCYVILIRPDSNIIKKHKGKVLN", "length": 850 }, "evidence": [ { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I6GK53-1", "protein_name": "Vomeronasal 2 receptor, 33", "gene_name": "Vom2r33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLCTFLFVLLGCLPGSALSEPRSWILPRQSPHFDRPGDVMVGGSFSIFCFSDGTLSNFTAPPTGLQASRVSMWGYRVAQSFVFAIEEINKSTQLLPNLTLGFSIQNSGDSVHGALYETMGFLTGQEEPIPNYTCCHGSPQAALVGDTRSSLSLPMARLLGLYKFSQISYSSSLPSLSDKIQFPSFLRTLPSDLTSCHAVTQLIIRFQWSWLIILSQDDDFGEQASSLATQQLSAAGVCIEFHLDVPSQHSLGKIEETVQKMQKCTARVVLVFLSNSNFQLILSGLLAASVSGQVWVSNDTLHIAMALSIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLHPSQIPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQVCSGNESLKNKPYPFPEVSKIDAAYTAVYSIAHALHDMVACEHQDGIDTNPQDFHPWQLLHVLKKVHFRTPDGSEIMFDANGDLVTKFDILQGQKTLNGVFHLVHVGMIDPQASSGNIMMIQLKEDLQVSSMNAEITVPTSICSERCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALMAILLAGLALLVLGVFLKHRDTPVVRVNNRTLSYFLLISLSLCSLCSLLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTVTVVLAFRVTKSGSRIQVCLSPGASTSVVLIASLIQVVLCGVWLATSPPFPERDMISEPQHIVIQCQEGSGATFFCVLGFLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHCAHQDRQCSLFH", "length": 864 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GKI6-1", "protein_name": "Vomeronasal 2 receptor, 71", "gene_name": "Vom2r71", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKMCAFTISSLLLKFSLILCSFTEPSCFWRIQNNEDNDGDLRSDCGFVLITYEGPIEENFYNNVINFRIPARRYEVFLVLLFATDEINRNPYLLPNMSFMFSRIVGMCEDTLGSLERKYTPQSNSWKFINYNCGIQEVCDVQLTGPSWTTSLKLAINSRNPKVFFGPFNPNLSDHDQFPYVYQVATEDTCLSHAMVSLMLHFRWTWIGLVITDDDQGIQLLTDLREEMERHGMCLAFVNMIPETMQIYMTKAKIYDNQIMTSSAKVVIIYGEMNSTLEVSFRRWAYLAAQRIWITTSQWDVITTRKDFSLDFFHGTFTFAHHNVELPKFRHFMQTMNTSKYPVDISQSMLGWNYFNCSISKNSISKIDHFTLNNTLEWLAQHKFDMFLSEEGYNLYNAVYAVAHTYHELILQVESQKMAEPKGLFTDCQQVALLLKTRAFTTPVGELVNMNHRENQCAKYDISIAWNFPQGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTLIPTSMCSVACIAGFRKIHQKQVTHCCFDCAHCPENEVSNETADMEQCVRCPDDKYANLEQTYCLQRVVSFLAYEDPLGMALGCTALCFSTLTVLILFTFLKYKDTPIVKANNCLLSYILLISLIFCFLCSLLFIGHPNHITCILQQTTFGVFFTVAISTVLAKTITVVMAFKISTPGNRMKGMLTSGAPNLVIPICTLIQLVLCGIWLGTSPPFIDRDIQSEPGKTIVICNKGSIFAFHFTLGYLDSLTLMSFAVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTKGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRTDSNFLQKYKDKFHY", "length": 849 }, "evidence": [ { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL30-1", "protein_name": "Vomeronasal 2 receptor, 3", "gene_name": "Vom2r6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTIAFFPLKFCLILCSLTEPNCFWRIKKIEVYDGDLQNDCGFVLFTLESPIEENFYNHIINFRIPARKYEFFLVMFFATDEINKNPYLLSNMSLIFSFIFGMCEDTMGVLDKAYLHQNNYFDLLNYNCGRKKRCDVKLTGPSWKTSLKLSVNSRAPKIFFGPFNPNLSDHDQFPYIYQIATKDTYLLHGMVSLMFHFEWTWIGLVITDDDQGIQFHSDLREEMQRHAICLAFVIMIPESIKLYNTKFKIYDQQLMTSSAKVTIIYGKMISTLGLSFRRWAYLVARRIWITTSKLDDITYDKDFSLDFFHGTVIFVHHHNDIATFRNFMQTINTSKYPVDISQSMGQWNHFNCSISKNKKKMDFFMLKNPLEWLKQHTFDMVLSEEGYNLYNAVYAVAHTYHELIFQQVESQEMAKPKGLFTDCQKVASLLKTRVFTNPVGELVNMNHKENQCAKYDIFIIWNFPKGLGLKVKIGSYFPCLQQSQHLHISEDWEWVTGETLVPSSVCSETCTAGFRKSHQKQTADCCFDCVQCQENEIANDTDMEQCVRCPDDSYANLEQTECLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYRDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQATFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRKMMIKGATNLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKVIIICNKGSVTAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVIVEVFSILASSAGLLGCIFVQKCYVLLVRPDLNVLQK", "length": 841 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N5X2-1", "protein_name": "Olfactory receptor CW1 precursor", "gene_name": "olfcw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTPVLRAIHLVFFLFYPIQSNSEANCKLWKELDLTVVHKEGDVILAGMFPIHSKGIDQELNFRNQPDQRKCWGFNMRVFRWSQAMIFFIEEINRNPTLLPNITLGYRLYDTCGLIALSLRTALSVVSQPMKRSSSEMCSSPSIPIIIGDSGSTLSMAISRLLNLFHIPLVSYFASCACLSNKHQFPYFFRTIPSDVNQANALARLVKHFGWTWVGTVGADDAYGRTGIDLFTAAVTQLGVCVSYRIIIPKLPTQQQLQDIVRTIRDSSAHVLVAFAIEEDIKPVVDEIVLQNVTGKQWVASEAWVTSTLISTKENFPSLSGTIGFAIRRAEIPGLKHFLDSIQPLADPYNVFAREFWETQFQCTLNTSLPTSSTMDPVNYSHSCTGMERMQDTQSIFNDVSQLRVTYNMYKAVYTVAHALHNLLLCQREHRSALTQQCPDIHNLQPWQVIEVLRKVNYTNMFGDLIYFDENGDPVGSYDIVNWQKGGDDVPVQYITVGRFDSSLPKGQQLVLNQNKIVWHGGTNKVPVSVCSASCPPGYRKVRLEGQPVCCYDCMLCAEGSISNTTDQAECLLCPEDFWSNKHRNYCVPKEIEFLSYLEAFGMVLAAIAILGAVAAISVGVVFFRHRDTPLVRANNSELSFLLLISLTLCFICALTFLGQPSHWACPLRRISFGLTFALCLSCLLSKTLVVLIAFKSTLPGNNTARWFRPPQQRLGVFICSLLQGGVCIAWLTTASPYPVKNTWLYRDRIILECHLGSVVYFCCVLGYIGCLAAFCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSYGVLLCIFAPKCYIIIFMPEKNSKKYLMTQK", "length": 866 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PU52-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWISLNIFLYLSLNCIFAASVVNPGTCQLQGHFKLNGMYQDGDFILGGLFEVHFFTLFPKLSFKSEPEPPYCEKFDMESFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCVMLGMAFRAAISLASGTEEYFSNLNCTGPPPVIGVVGDPGSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVRILSHFGWTWVGLIYSDDDYGIYASVSFQQEMQQFGSCISFSEILPHDNNPKDIQRIMEVIKASTASVVVVFSTSSYLMPLIDEVVLQNLTGRQWIASEAWATSPVFHTPRYLPFLGGTLGIAIRRGEILGLQEFLLHIHASNNPKDNMLKIFWENMFRCSFETRSKDTIGEQEKSICTGHEDLSTTKTPYTDVSGLRASYNVYKAVYALAHALHDLMECEEGRGPFDGNSCGNITNLKPWQLVHYLQKVNFKTGFGDHVSFDENGDALAIYDVLNWHPSSDGSIRLHTVGVVNEGAGTGKVLSLDESALYWNFQTKNPPRSVCSASCPPGTRQAMRKGLPICCFDCLPCGDGEISNATDSTECVTCPDEFWSNFDKNQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHLNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGTMKWFGAAQQRCTVLVLTALQVVICAVWLSNASPTPIKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKKAIIRRETKKR", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q146-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYQDGDFILGGLFEVHFFTVFPDLTFTTNPKSPYCEIFNMEGFQHAQTMAFAIEEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLTSGTEESFLNLNCSGPSPVIGIVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSNRKKYPSFFRTIPSDAFQVRAIVQVLKHFKWTWVGLLYSDDDYGVYAAQSFQQEMRQFGLCAAFSEFLPHDNNPRTIQHIMGVIQGSTAKAVVVFAPSSFLIPLMNEVVLQNMTGRQWIASEAWATSLESHIPSFQPFLRGTIGIAIRRGEIQRLHDFLLRIRPSNDPKNYMLRIFWENMFGCSFGKGDTEGEQVIKVCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHALHDLMECEEGKGPFSKNSCADKTNLKPWQVVHYLQNVNFTTGFGDYVSFDKNGDALAIYDVLNWQPSSDESIRIYTVGVVKEGTETGMVLTLDEDAIFWNFETRKPPRSVCSESCPPGTRRATRKGLPVCCFDCLPCGDGEISNTTNAVECFLCPDEFWSNQYNNHCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVIFVFALHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHVVFGISFVLCMSSILVKTMVVIAVFKSSRPEGKGAIKWFGAVQQRSTVVVLTVLQVLICAVWLSTASPTPYKNNQYIRSKIVYECAIGSVVGFSMLLSYIGFLAAASFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFVPAYVSSPGKYTVAVEIFAILASTFGLLIAIFAPKCYIILLHPERNTKNVIMGRETQNK", "length": 829 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q166-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWSPLIICLYLSYNFKSAASILMGSCQLQGHFGLNGMYQAGDVILGGLFEVHLLAVFPELSFRSAPEPPYCEQFDMASFQQAQTMVFAIDEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLVSGTEELFSNLNCTGSPPVIGIVGDSNSTPSIAISSVLGLFRVPIVSYFATCSCLSNRKQYPSFFRTIPSDAFQVRAMVNILKHFGWTWVGLIYSDDDYGNYAAQSFLQDIQIYGGCVAFTEILPLNNNRKYIEHVVGVIQASTARVVVVFSTSTYVLPLMDEVVLQNVTNRQWIASEAWATSPMFHTQRLLPFLGGTLGIAIRRGEIQGLHEFLLHLRPKNDQHNNMVRIFWEKMFGCRFNPGGKGDKQCSGQEDLSSIDTAYTDVKELRASYNVYKTVYALAHALHDLTECDEERGPFSENRCADITNLQPWQLVHYLQKVNFTTGFGDHVSFDKNGDVLAIYDVMNWHPSSDGSISVRTVGVVNEGAASGKVLTLDEDAIYWNFKIKKAPQSVCSESCPPGTRQATKKGLPVCCFDCLPCGDGEISNVTNAIECTVCPDEFWSNKDKDQCVPKEVEFLSYEDPLGISLTTACLLGTCFCALVMIIFCQHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGSMKWFGTTQQRCTVLILTALQVVICIVWLSNSSPAPHKNSQHISSKIVYECAIGSLAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVTSPGKYAVAVEIFAILASSFGLLGAIFAPKCYIILLHPEKNTKKAIMGRQITK", "length": 860 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q1C5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNAHLLFTVKMLCIARLCIAVCGVDLGTCILQGDAQPPALSEDGDFIVGGAFTIHYYVRTEKYTYTRRPQPLECSGSMDFRELRFARALQFAIQEINNSSDLLPGIFLGYHIYDSCGSVPMAIKVALQLANGLDPKYNDTDSCAKSAAVLALVGDSASTPAISISRIFGPFEIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEKEGICVEYSEAYYRTYPLSKLKRVADVIRRSTARVIVAFVAAGDMRFLLEELSKEPLPPMQWIGSEAWVSDPQMLRFNLSIGTMGVAVPRSLIPGFRKFLLDLSPYKVLKFPLLTEFWESSFSCSLQQQTDPSTGMPACDGTEDLGRLKNPYTDTSQLRVSNMVYKATYAIAHALHGIVCNETQCSKNIKVKPRQVFDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPEGQEFSLNKAIIWYDGSEKVPVSVCSENCPPGTRKAVKKGRPVCCYDCIPCGEGEISNKTDSPDCDKCPPDYWPSTEKDKCLPKPVEFLSWDEILGIILAVLSVSGSLLALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWVVLGYIGLLASLCFVLAFLARKLPDNFNEAKFITFSMLIFSAVWITFIPAYVSSPGKFTVAVEIFAILASSFSLILCIFAPKFFIILFRPEENTKKHLMGKVQSKSY", "length": 856 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RHU5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCCYICVTLIASTGTCQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMTSFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTSRQWIASEAWVTAAVFRTPYFQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTTNTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEGSIKLHNIGVVNEVATGMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTSRAMRKGFPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDRCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AUZ8-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcv3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHSLETMTILLLWLLVYHLSVLNPAQASKCLLQNEFEPGLMANGDFVIGGIFPLHYNQEMPDLNFTYKPGPVKCNGFDTRAFRWAITMKLAVEEINKRVDLLPNYTLGYKIFDSCAYPLTGQRSAVAVLNGPNELESPLCADAAPLLAVIGESGSAQSIVVSRILQPFGIPMISYFSSCACLSDRREFPTFFRVIPSDAYQVKAIAKLLRHFNWTWIGVIRGDHEYGRFALQGLLKELEGTGICVAYQKMIPLLYDRQKALEIIHVMSHSTARVVVVFSAEGELTPFLRDYMEQNVTGIQWIASEAWVTSSVFAGSEFDPFLGGTIGFGIRQGQIPRLKEYLTTVNPERYPTNPLVYELWGALYGCSPSWSNLSSHLPSCTGKETVRLQYSAYLNTSSPRISYNVYKAAYAIAYSLHNLIYCTPGKGPFSNSTCANAPHIYPWQLQQYLQEVSFTISGEKVNFDMKGDSIPSYDLINWQRGSAGNIEFINVGMFDGALESGQELVIKEEAIMWPGHQTEVLVSVCSNSCAPGFRKAVRRGQPLCCFDCVPCDSGKISNETDSLDCIACSEDYWSNADGTVCIPKVVEFLSHDAMGLTLTVIAVAGACLTLAVFSVFLYYKNTPVVRINNSELSFFILLSLTLCFLCALIFIGEPTSWSCMLRHTAFSITFSLCISCILGKTLVVLAAFTATRPGNNLMKWLGPTQQRIIIFCCTLIQVLICTVWLVASPPFPYRNTKYQQSKIILDCSVGSDLAFWCVLGYIGLLACVCFFLAFLARKLPGNFNEAKYITFSMIIFCAVWLAFVPAYVSSPGKFTTAVEIFAILASSFGLLLCLFTPKVYIILVKPEKNTKQHLMGKDK", "length": 859 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AV03-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYNNVLLIVTLQCIITRLYVVYGNRLGSCILQGDPQPPVLFDEGDFIIGGAFSIHYYLRTEKHTYTMRPQSLECSGSMDFRELRFARVLQFAIQEINNSSDLLPGITLGYRIYDSCGSVPMAVKLSFQLANGLDLIFNDNDSCSKSAAVAALVGESGSTPSISISRLYGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEEEGICVEYSEAYYRTQPRSKLMRVADVIRRSTARVIVAFMASGDMRLLLEELSQQPLPPMQWIGSEAWFTDPEMLRFNMCIGGVGFAIPRSVIPGFRTFLLDLSPQRAMKFPLLTEFWESSFSCSLKQQTGPSTGMPACDGTEDLGRLKNPYTDTSQLRISNMVYKATYAIAHALHGIICNEKKCNKNIKIEPREVLDKLKQVKFSKNNYSVSFDAYGDPVAVYELVNWQLQKDGSIDFVTVGKYDSSQPKGKEFSLSRAIIWYDGTEEVPVSVCSESCPPGTRKAVQKGRPVCCYDCINCADGEISNDTDCLDCHECLSDYWPNNEKNKCLRKPVEFLSWDEILGIILAAFSVAGSLVALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPSQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFGLILCIFAPKFFIIIFRPERNTKKHIMGKVPSKAL", "length": 856 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B2Z8-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcg8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLFLYSVLSLYHLNTKAENTLCQMIGNPKYPLLSKDGDITIGALFVIHSEVSLPSFAFTQKPNLLSCSSLNIKDFRLAQTMIFAIEEINKNTNLLPNISVGYQIYDTCGSRFHSMSATMALMNGPKNSEGYTCNEQSSVHAIVGETESSNTIILSRTTGPFKIPVISPTATCECLSNRKEFPSFFRTIASDYHQSRALAYIVKHFGWTWVGAVNSDNDYGNNGMATFQKTAKEVQICVEYSVKFIRTETEKIRNVVNVIKKGTAKVIVAFLTGFEMKSLLEQLSSQNITGLQMIGVEAWITSKTLITSKSFHVLGGSLGFAVRKIQIEGFADYVMKAFWDTAFQSFSNADLNYSQYQDLLLVKNYNEDVLEQRFVSYVYKAVYALAHSLHSLLRCTEQGGCGKALTIQPHQLVEALRKVNFTVKMGDQVWFDSTGGVIAQYDVVNWQQNSDGSVQFQSVGYYDASLSPDQRFMLNTEKIVWAGGQLEKPRSVCSESCPPGTRKASQKGRPVCCHDCIPCADGEISNETDSNNCKQCPGEYWSNANKNKCVTKAVEFLSFTEVMGIILVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSIPFIGRPTQWSCMLRHTAFGITFVLCISCILGKTIVVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTLIQGLICVIWLTKSPPFPYKNMKYFQEQIILECSVGSTIGFWAVLGYIGLLAVLCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKLTVAVEIFAILASSFGLLFCIFAPKCYIILLQPEQNTKQQMMAKTPSKI", "length": 832 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PD42-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWITLCIYLYLSLNYICAHSILRTSDSCRLQRRFHLNGMYKDGDVILGGLFQVHFFTVFPEQSFRTEPEPPFCEKFDMESFQQAQTMAFAIEEINKNPNLLPNITLGFHLYDNCVRLGMAFRAAISLASGTEESFQNLNCTGPPPVIGIVGDPSSTPSIAISSLLGLFRVPIVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLIYSDDDYGVYAAQSFHLEMQMFGHCVAFSEILPHNNNQRDIQRIMGVIQASTARVVVVFSTSSFLLPLIDEVASQNMTGRQWIASEAWATSPVYHSPRLLPFLGGTLGIAVRHGEIPGLHDFLLHLGPGNESRNNMLRIFWENMFGCSFEPGVKDTNSEIKLCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHGLHDLMQCEKGRGPFRGESCADITNLKPWQLVHYLQKVNFTTGFGDHVSFDENGDALAIYDVLNWQPSSDGSIQIFTVGVVKERTETGMVLTIDEDAIYWNFETKKSPQSVCSESCSPGTRRATRKGLPVCCFDCLPCRDGEISNTTDAIECMLCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGSCFCVLVMIIFGLHRNTPIVRANNSELSFMLLLSLKMCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGAMKWFGAAQQRCTVLVLTVLQVVICSVWLSTASPTPYKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKNAIMGRETQKR", "length": 867 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PFV7-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcg9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLYLCTLLLFFKLKVSVGNASCKIMGEPKYPLLFKDGDVTIGALFPVHSIETAPSFEFTQKPQLLSCSSVNLRDFRLAQILIFAIEEINRSESLLPKLSLGYKIYDTCSSKLSSMSATMALMNSFEFAGRDKCNGQTSVHAIIGETESSATVILTRTTGPFKIPVISHAASCECLSSRKEYPSFFRTISSDYHQGRALAYIVKHLGWSWVGAVNSDNDYGNYGMAIFLNTAHKEGICVEYSEKFYRTEPEKLKKVVDTIKKSTAKVIVAFISFLEMRLLVEQLSAENITGLQIVGVEGWTTSKSLITPKTLNVLRGSLGFAMRKIYIEGFAEYVLKPFWDTAFPCIPNQRNDSWVILNCSRYQDLLVLKNYIEDVPEHRFSINVYNAVYAVAHALHSLFKCKEQEGCEKDLLTQPQQVVDALKKVNFTVKMGDRVWFDSTGATLAQYEVVNWQQNSDGSVNFKKVGYYDASLPPDQRFVLNIKEILWAGGNLKKPRSVCSESCPPGTRKAAQKGRPICCYDCIPCADGEISNDTDSNNCKQCQGEYWSNADKNKCVQKSVEFLSFTEVMGIVLVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTQWSCMLRHTAFGITFVLCISCVLGKTLLVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTFIQVLICVLWLSISPPFPHKNMKYYEEKIILECSLGSTIGFWAILGYIGLLAALCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSISLLLCIFAPKCYIILLKPEQNTKQYMLGKTTSKFY", "length": 839 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPM0-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcg12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVFFCTLLIFFQLYAKAEKPICIMMGDPKYPLLSKEGDISIGAVFPVHSIETLPLFKFTQKPQLLSCSSVSIRDFRMAQIMAFAIEEINRNESLLPNVSLGYQIYDTCGSGLSLMGANMALMNVQEFASRGSCNGQSPVHAIIGETESSNTVILSRTTGPFKIPVISPSASCECLSNRKEYPYFFRTIASDYHQSRALAYIIKYFGWSWVGAVNSDNDYGNHGMAIFLSTAEKEGVCVEYSVKFQRTEPEKLKKVVDTIKKGTSKVIVAFLTEFEMKNLLEYLIIQNVTGLQVIGVEAWITANSMIKPNSFHVLGGSLGFAVKKLNIEGFEDYVTKAFWETAFPCSQTSQKENSQYKLICNIYRDLLVLKNDNKDVPEQRYASNVYKAVYAVAHSLHNILKCRENGACETDMKIQPQQVVEALRKVNFTIKMGDCVWFDSTGAVVAQYEVVNWQPDYNGSIQFKPVGYYDASLPPNQRFVINTENIIWAGGQLKKPRSVCSENCPPGTRKAVQKGRPVCCYDCIPCAEGEISNETDSNNCKQCPGEYWSNAEKNKCVLKAVEFLSFKELMGIVLVFFSLLGAGLTTLVAILFYSKKDTPIVKANNSELSFLLLFSLMLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSDVMKWFGPIQQRLSVLVITIVQVLICVLWLAVSPPLPYKNTKYFKEKIILECSLGSTIGFSAALGYIGLLAILCFILAFLARTLPDKFNEAKFITFSMIIFCAVWITFIPSYLSSPGKLTVAVEIFAILASSFGLLFCIFLPKCYIIMCKPEQNTKLHIIGKLNK", "length": 837 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2U8-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLCEMWITLNICLYMYFNHISGVFTSESCQLQGCFKLNGMYQDGEFIIGGLFEVQNLKVFPELSFTNEPELPQCEEFYMASFQQALTMVFAINEINSNSKLLPNITLGYQIYDNCLRLGVAFRAAMSLVSGTEESSNLSCTGPPPVIGIVGDPGSTQSITISSVLGLYRVPMVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLLYSNDDYGIYAAQSFQQEMQILGGCVAFSEMLPYDNNGRDIQRIAGVIQKSTAKVVVAFSTDLASLMDELLLQNVTGKQWIASEAWTTTPVLQTPQYLPLLGGTLGIAIRRGQIQGLYEFLKNLRPDKNPKNSTIRIFWETMFGCKFEVGGKKVDEQQERGRNKCSGQEDLNNSETAYTDVSELRASYNVYKAVYALAHALHDLVKCEEGKGPFTGNSCADISNLKPWQLVHYIQNVKFTTGFGDHVSFDENGDALAIYDVMNWHPRSDGSIIVHVVGVYEEAILGKVLTLDEDALFWNFETKKPPDSVCSESCPPGTRRARKKGLPVCCFDCLPCGDGEISNTTDSPECFICPEDFWSSPENDRCVPKEMEFLSYDDPLGISLTTASLLGTCFCVLVLVIFAYHHNTPVVRANNSELSFLLLVSLKFCFLCVLLFIGRPRLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKTSRPEGKTSIKWFGSAQQRGTVIALTSAQVAICTVWLSSASPTPHKNNQYIHSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFMARKLPDNFNEAKFITFSMLIFCAVWIAFVPAYASSPGKYAVAVEIFAILASSFGLLAAIFAPKCYIIILHPERNTKKAIMGRSTQNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T5D2-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCYYICVTLMASTGICQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMESFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLHNLTSRQWIASEAWVTAAVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTANTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEESIKLHNIGVVNEVATEMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTRRAMRKGLPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDQCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSLAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6G6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAILLFCLFLSCNFICVTLMVSSGTCQKQGHFTLNGMHQDGDFVIGGLFEIQSYVKVYPEISFRTQPKLPNCDLFYMTSFQQALTMVFAISEINNNPNLLPNITLGYQIYDNCLRLGVAFRAATALISGTEETISDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRLPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAMVQTMRHFGWTWVGLIYSNNDYGIYAAQSFHKEMQLFGHCVAFSEILPQDNNPRVIDHIIGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTGRQWIASEAWVTSTVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETEDKETFGQQIKKVCTGQEDLSITNTPYTDVSGLRAPYNVYKAVYALAHALHDLMQCKEKRGPLSEKNCADITDLKPWQLLSYLKKVNFTTGFGDPVSFDNNGDALAIYDVLNWQPSSEGSIKLHSIGVVNDEVATGMVLRLNKDEIYWNFEAQKAPRSVCSESCPPGTRKAMRKGFPVCCFDCLTCGDGEISNTTDAIKCTVCPDEFWSNFNKDQCVPKEIEFLSYEDPLGISLTTASLLGTCFCALVMIIFAFHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFNSSRPEGKGAMQWFGAAQQRCTVLVLTVLQVVICAVWLSTSSPTPHKNNQYVRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRETKKY", "length": 869 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6Z6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcq17", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLYLSLCLCFKHIYADSIHRLRSCQLQGRFKLNGMYQDGDFILGGLFHVHFFTVFPELSFRMEPQQPYCEKFNMEGLQHAQTMAFAINEINKNPTLLPNITLGYHLYDNCVMLRMAFRAAMSLASGTEDSYSNLNCTGPPPVIGIVGDASSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKHFKWTWVGLLYSGDDYGVYAAQMFHKEMQLSGHCVAFSEILPNDHNPKDIQRIIRVIQGSTARVVVVFALSSFLIPLMDEVVLQNMTGCQWIASEAWATSLEYHTPRFLPFLGGTLGIAIRRGEIEGLHEFLLRIRPSNDTSQNIVRIFWENLFGCRFETGGLKTGREQEKMECTGQEDLSTTNTPYTDVSGLRASYNVYKAVYALAHGLHDLMQCEEGRGPFIGNSCADITSLKPWQLVHYLQNVNFTTGFGDHVTFDKNGDALAIYDVLNWQPSSDGSITVHKIGVVYEGATTGMMLTLDADAIYWNFETKKPPLSVCSESCPPGTRQATRKGLPLCCFDCLPCGDGEFSNTRDAVECMMCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGAMKWFGASQQRCTVLVLTALQVVICAVWLSTASPTPHKNNHYFRSIIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFALLLAIFAPKCYIILLHPERNTKNAIMGRETQNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TDV0-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfck1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRISLGWVVCLVKEMHVNLLLILTLLCIRRLFPAVCGVHLGTCILQGDPQPPSLFSKGDFVIGGTFTIHYYLRTEKRTYTVRPQPLMCSGSMDFRELRFARVLQFAIQEINNSSNLLPGITLGYHIYDSCASVPMVIKVAVQLANGLQLAFNDTDSCAQSSEVLALVGESGSTAAITTSRLFGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEVEGICVEYSEAYYRTQTRNKLQRVADVIRRSTARVIVAFMAAGDMRFLLEELSQQPPPPMQWIGSEAWVTDPQMLRFNLSIGAVGFAIPRSVIPGFRKFLLDLSSEQALKIPVLKEFWESSFGCSLKQHTGYFSGMPACDGTEDLGTLKNPYTDTSQLRISNMVYKATYAIAHALHGIVCNGKLCDKNIKVEPRKVSDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPKGQEFSLNRAIIWYDGTEKVPVSVCSESCPPGTRKAVKKGRPVCCYDCINCADGEINNETDSLDCHKCQPDYWPNAEKIKCLPKPVEFLSWDEILGNTLAAFSIAGSLVALSMALVFYKNRVSPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFSLILLIFAPKCFVIVFRPEENTKRHLLGKVPPKAL", "length": 870 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUY1-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWVILHIYFFISCNYMSVALMASSGTCQLQGHFTLNGMYQNGDFLIGGLFEIQYLKAFPGLSFRTEPKLPHCENFYMTSFQQAITMVFAINEINNNPNLLPNITLGYQMYDNCLRLGVAFRAATALISGTEETLSDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMIQILRHFEWTWVGLLYSDDDYGINAALSFHHDVQQFGGCVAFSEILPNDNNQMAVQHIVRVIQNSTAKVVVVFSTSSYLLPVIDEMLLKNITGRQWIASEAWSTSPVLLNPRLRYVLGGTLGIAIRRGEIEGLDNFLLRLRPDNFSQNSMMRIFWENMFECNFDTIGGLRTKLCSGQEDLRSKFTPYTDVSELRASYNVYKAVYALAHALHDLMHCEEGRGPFSENRCVDISNLKPWQLVHYLQRVKFTTGFGDHVSFDKNGDALAIYDVLNWQLSSEESVTVRRIGVVDEGVTTGKVFTLDENAIYWNFETNKPPRSVCSESCPPGTRQATRKGLPVCCFDCLPCGDGEISNTTDTTECIACPNDFWSNPEKDQCIPKEVEFLSYEDPLGISLTTAAMLGTFICALVMTIFAHYRNTPVVRSNNSELSFLLLLSLKLSFLCVLLFIGQPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKNAMKWFGAAQQRGTVLILTALQVLICAVWLSTASPTPHKNSRYIRSIIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDSFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIIILHPERNTKKAIMGKGTKNK", "length": 863 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UVL1-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLTWHRLFIKATPSKVFIINNIHRGELKRNVEMWIIAKICLYLSFSCISVASIFRSGPCQLQGQFRLNGMFQEGDLILGGLFEVHFLTVFPEQSFRTEPEPPYCEQFDMASFQQAQTMVFAIDEINRNPNLLPNITLGYYLYDNCVKLSVAFRAAMALVSGTEESFSSLNCTGPPPVIAIVGDPGSTHSIAISSILGLFRVPMVSYFATCSCLSDRKTYPSFFRTIPSDAFQVRAMVQILKRFGWTWVGLLYSDDDYGIYAAQSFQKEMQLFGACVGFSEMLPRDNNHEDIQSIVEVIQTSTARVVVVFSTEAYLLPLMDEVALKNVTGRQWIASEAWATSPVFHTQHLLPFLGGTLGIAIRRGEIQGLKEFLYYLHPDSNTRNNIVRIFWENIFGCSFEIGGRERKVCTGQEDLKSTNTAYTDVSGLRASYNAYKAVYALAHALHDLMQCEDGRGPFSGNKCADQINLQPWQVVHYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWQPSSDGAISVSTVGVVNEGASMKMVLTLKENSIFWNFKNRKPPQSVCSESCPPGTRQVRRKGLPVCCFDCLPCADGEISNTTDAIECKICPDELWPNPNKDQCVPKEEDFLSFEDPLGISLTTASLLGTCFCALVMVIFSHHRNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPKLWTCQLRHAAFGISFVLCVSSILVKTMVVIAVFKSSRPESKSAMKWFGVAQQRGTVMALTTLQIVICTVWLSMASPKPYKNSLYISSKVVYECDIGSVVGFSLLLGYIGLLAAVSFLFAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYMILFHPERNTKKSIMGRATQIK", "length": 894 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V5L1A2-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSVSMWGYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFSQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSHQSLGKIEETVQKMQKCTSKVVLVFLSNSNFQLILHGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVPSSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPSWLKQGHHI", "length": 845 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AB13A3P1-1", "protein_name": "Olfactory receptor CG7", "gene_name": "olfcg7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSANSLFMVSLTFRMILYFYTILFLRCFQAKTENAFCQIIGEAKYPLLSKDGDVTIGGIFAIHSKETLPSFEFQQKPQPLLCSSVNLRDFRLAQIMIFAIEEINKSENLLPNVSIGYRIFDTCGSRLSSMSATMGLMNELKFAAGETCNGQSPIHAIIGETESSATVILSRTTGPFKIPVISHSASCECLSNRNDYPSFFRTISSDYHQGRALAYIVKYLGWSWVGAVNSDNDYGNYGMAIFLETAQKEGICVEYSVKFYRTETEKLKRVVDTIKKSTAKVIVAFVSFIEMGLLIEQLSIQNITGFQIIGVEGWITSKNYITTNSFHSMGGSLGLALRKIHLEGFLDYVTKSFWSTAFPCSQTEGILPTVGCSKYKDLLPLKNYTEDVPEHRYSSHVYKAIYAVAHSLHSLLKCKEGEDCEKGHATQPQQVVEALKKVNFTVKFGDRVWFDRTGATVAHYEVVNWQQDTDGSFQFKQVGYYDASLPPDQRFVLNIESIIWPGGNLEKPRSVCSESCSPGTRKAAQKGRPVCCYDCVPCADGEISNETDSVNCKQCPREYWSNGEKNKCVLKAIEFLSFTEIMGIVLVCFSLFGVGLTAVVAILFWSKMDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMVFKATLPGSNVMKWFGPTQQRLSVLAFTFIQVLICVLWLTISPPFPNKNMTYYKEKIIIECSLGSTISFWAVLGYIGLLAVLCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSFGLLLCIFAPKCYIIICKPEQNTKQHVMGKTSLKVQ", "length": 851 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TCB3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNFGAGLRTGSRNGNEKWKRMTFCRSSAFCHMFSSTLYLISSMARHAVVLRAGACQLQGRFRLNGMYQDGDVILGGLFEAHFFTLFPELTFRTEPAPPYCEIFNMESFQYAQTMAFAINEINRNPSLLPNISLGYHLYDNCVMLGMALRAAMSLVSGIEESFLNLNCTGPPPIIGVVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMIQLISHFGWTWIGLLYSDDDYGTYAAQSFHQEMQLFGFCIAFSEPLRYDSNPRDIQRLMEVIQASTSTVVVVFSPSTLVIPLMNEVVLQNMTGRQWIASESWATSPVFYTPRFLPFLGGTLGIAIRRGEIEGLREFLLQLRPKNDPRNNMLKIFWENMFGCSFETGPHVKNVCTGQEDLSTTNTPYTDVSELRAANNVYKAVYALAHALHDLMKCEEGKGPFSKNSCAEISNLKPWQLVHYLQKVNFSTRFGDHVSFNKNGDALAIYDVMNWQPGSDRSIRIHTVGVVSEELEKGLMLTLDEDAIYWNFETKKPPQSVCSESCPRGSRRATRKGHPVCCFDCLPCRDGEISNTTDATKCTVCPDDFWSNLYKDQCIPKEVEFLSYNDPLGISLTTASLLGTCFCAFVMVIFVHHHNTPIVRANNSELSFLLLFSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKMAMKWFGAAQQRCTILALTAIQVVICVVWLSTASPTPHKNNLYIRSIIVYECTIGSVTGFSMLLGYIGLLAAVSFLIAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYSVAVEIFAILASSFGLLVSIFAPKCYIILLHPERNNKKAIMGRETH", "length": 888 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LAY5-1", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "Vom2r5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTIAIFSLKFCLILCSLTEPNCFWRIKSSEDNDGDLRSDCGFVLFTHEGPIPEDFYNDIINFRIPARKYEFFLVLLFATDEINKNPYLLPNMSLIFNIIFGLCEDTLGVLDKAYLHQNSNSELFNYYCGINQLCDVDLTGPSWTTSLKLSIYSRTPKIFFGSFNPNLSDHDQFPYIYQIAAKDTYLFHGMVSLMFHFGWTWIGLVISDDDQGIQFLSDLREEMQRHAICLAFVNMIPETMQIYKTRVKIYDQQLMTSSAKVVIIYGEVNSTLELSFRRWAYLGAQRIWITTSQWDVITHKKDFSLDFSHGTVTFAHHHNDIAVFRNFMQTINTSMYPVDISQSMLQWNHFNCSISKNKKKMDCFTFKNPLEWLIQHTFDMVLSEEGYNLYNAVYAVAHTYHKLIFQQVESQKMEEPKGLFTDCQQVTSLLKTIEFTNPVGELVDTKHKENQCATYDIFITWNFPQGLGLKVKIGSYFPCLPQSQQLHISEDWEWVTGETLIPPSVCSMTCTAGFRKIHQKETADCCFDCVQCQENEIANDTADMEQCVKCPDDSYANLEQSQCLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLYIGHPNQATCILQQTTFAIFFTVAISTVLAKTITVVTAFKLTTPERRIKKIMIKGAINLLIPICTLIQLVLCAVWLVISPPFIDRDIQSEHGKVIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKDMVIVEVFSILASSAGLLGCIFFQKCYVLLVRPDLNVLRK", "length": 842 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0T300-1", "protein_name": "Olfactory receptor CD2 precursor", "gene_name": "olfcd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANTLSLLLLLLLLHGHFLPATVQICDLVGQSALPVLSAERDINIGAIFSIHRNALLRLYPFTSKPEPTTCVRLNLREFKFAQTFIFAIEEINNNTQLLPGVTLGYKIYDACNAISPTLVSGMALINGYENTLSDTSCSQPPAVQAIVGESSSSPTTALAALVGPFNIPVISHFATCACLSNRKRYPSFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGITAFEDAAKQEGICIEYSEAILRTDPQEQFRKTVEVIKKGTSKVVVAFISFGDFAPLVKVIAENNITGLQWVGSESWITSRNLAETKEYSFLSGAVGFAIVNAKLVGLKEFLVNVHPDQEPKNKLLKEFWETAFQCSFSNSDSALCTGSEKLGELKNEYTDVSELRIEHKAYAAVYAVAHTLHNVFKDVKAPNNSKRELPTPQKVLQYMRNLSFTIKTGENIFFDASGDPVARYDLVNWQTAEDGSLQFKHVGIYDSSLPSKQRLQVNQEIMLWAGKSGLLPLSVCTESCLPGTRKAVQKGRPVCCYDCIPCAEGEISNSTDSSDCFSCDLEYWSNEKKDRCILKVVEFLSYAEIMGIILCIVSFIGLLLTVMVTCLFYLHKETPIVRANNSELSFLLLFSLSLCFLCSLTFIGRPTQWSCMLRHTAFGITFILCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLVQVIVCLLWLTLSPPYPYMNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSSPGKYTVAVEIFAILVSSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKL", "length": 848 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0T301-1", "protein_name": "Olfactory receptor CQ19 precursor", "gene_name": "olfcq19", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWVILNISIYLIFNFIMSASILGSNTCQLQGHFRLNEMYHDGDVILGGLFEVDFLTVFPDLDFKTEPEPPYCVQFDMESFQQAQTMAFAIDEINKNPNLLPNITLGYHLFDNCVMLGMAFRAAISMASGTEEFFNNINCTGPPPVIGIVGDSSSTVSIAISSILGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKYFRWTWVGLIYSDDDYGVYAAQSFQQEMQLFGGCVAFSEVLPHDNNLEDIKHITKMIQASTARVIVVFSTPSFLIPLIDELVLQNMTDRQWIASEAWATSFVHHSPRLLPFLKGTLGIAIRRGEIQGLYEFLLRLQPTNDPKNNMIRIFWEIMFGCNFETGGKKNSGDQVINICTGQEDLRTTKTPYTEVSELRASYNVYKAVYALAHALNDLMQCEDGRGPFSVNSCADITNLKPWQLVHYLQNVNFTTDFGDHVSFDKNGDALAIYDVLNWQPSSDGSIRAQTVGVVNEEVATGMVLTLDEDALYWNFESKKPPSSVCSESCAPGTRLATIKGLPVCCFDCLPCGDGEISNITGAVECTMCPDEFWSNLDKDQCIPKEVEFLSYEDPLGISLTTASLLGTCFCVLVMFVFAVHRNTPIVRANNSELSFLLLLSLKMCFLCALLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPESKGAMKWFGAVQQRCTVLVLTAIQVVICAVWLSTASPAPHKNNQYIRSKIVYECAIGSVAGFSMLLAYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIILLHPERNTKKAIMGKEAQNT", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2BE32-1", "protein_name": "Vomeronasal 2, receptor 121", "gene_name": "Vmn2r121", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLCAFTISFLFLKFSLILCCLSEPSCFWRIRNSEDSDGDLQRECHFYLWLIDESIEDNFVSDLNFRIAASEYELLLVIFFATDEINKNSYLLPNMTLMFSIIGGNCHDLLRSLDQEYTEIKGHMNFVNYFCYLDDSCAIGFTGPSWKTSLKLGLHSSMPLVFFGPFNPNLRDHDRLPHVHQVATKDTHLSHGMVSLMFHFRWTWIGLVISDDDQGIQFLSDLREESQRHEICLAFVNMIPENMQIYMTRATIYDKQIMTSSANVVIIYGEMNSTLEVSFRRWEELGAWRIWITTSQWDVIKNKKEFTFNLFHGTITFAHHKVEIPKFKKFMQTMNTAKYPVDISHTILEWNYFNCSISKNSSKMDHMTFNNTLEWTALHNYDMAMSDEGYNLYNAVYAAAHTYHEHILQQVESQKKAKPKRYFTACQQVSSLMKTRVFSNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYIPCFPKSQQLHICDDLEWAMGGTVPSSVCSVACTAGFRKIHQEETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANIEQTHCLSRAVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQVSCILQQTIFGVFFTVSVSTVLAKTITVVMAFKLTTPGRRIRGMMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTVILCNKGSVIAFHVVLGYLGSLALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSTRGRVMVVVEVFSILASSAGLLMCIFVPKCYVILIRPDSNFIKKHKGKLLN", "length": 847 }, "evidence": [ { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YWE3-1", "protein_name": "Vomeronasal 2, receptor 84", "gene_name": "Vmn2r84", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMCALTISFLLLKFSLILCCLKEPICFWRIKSSEYNDGNLQSECGYFVWTMKKLMKDDFYNVWLDFRIPASEYEFVLVMFFATNEINKNPDLLPNTSLVFSVMAGNCQDSLGNLDIQYMLTNDSLNYVNYVCDIDDSCAIGLTGPSWKTSLKLAIDSWTPTVFFGPFNPKLSDHDHFPYVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGVQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWAYLGARRIWITTSQWDVITNKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSVLRWNYFNCSVSKNSIKMDHFTCENPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILQQVESQKMAEDKGEYTECQQLAPLLKTRVFTNPVGEMVNMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTSVPSSMCSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETDMEQCVRCPDDQYANLEQTHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYRDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGGRMRGMMMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIDRDIQSEHGKTVIFCNTGSVLAFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYAILVRPDSNCIQKYKGKLLY", "length": 849 }, "evidence": [ { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZQ04-1", "protein_name": "Vomeronasal 2 receptor, 67", "gene_name": "Vom2r67", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTVAFLFLKFSVILCRTQLTEPNCFWRIKNSEDNDGDLQNDCGFILFTFKGRIEENFYNKLLNFINFRIPARKYEFFLVMFFATDEINKNPYLLSNMSLLFSIIFGMCEDTLGIVDEVYSQSNKGLAFTNFICGVESTCDIQLTGPFWTTSLKLAIYSKAPKLFFGPFNPNLNDHVQFPYVHQVASKDTCLSHGMASLMLHFKWTWIGLAISDDDQGIQFLSDLKEEMQRHGICLAFVNMIPENMQIYMTMAKIYDKQIMTSSAKVVVIYGKINSTLEVSFRRWGNLGAHRIWITTSQWDVITNIKDFNLDFFHGTVTFAHHHSDIAEFRNFMQTINTSKYPVDISQSMLGWNHFNCSISKNNSKIDYFTFNNPLEWLAQHTFDMVLSEEGYNLYNAVYAVAHTYHELILQQVESQKMEEPKGVFTDCQQVASLLKTRVFTNPLGELVNMNHRENQCIEHDIFIIWNFPQGLGLKVKIGTYFPYFTHNQQLHISEDLEWATGGTLVPSSMCSMTCTAGFRKIHQKETADCCFDCVQCPENEVSNDTADMEQCVRCPDDSYTNLEQTQCLQRTVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQDTCILQQTTFGVFFTVAISTVLAKTITVVTAFKLTTPGRMIRRRMIKVATNFLIPICTLIQLALCGIWLGTSPPFIDRDIQSEHGKVIIICNKGSIIAFYFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMIVVEVFSILASSAGLLGCIFVPKCYVLLVRPDLNVLQKKDELLYQ", "length": 854 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZXT3-1", "protein_name": "Vomeronasal 2 receptor, 69", "gene_name": "Vom2r69", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTVSFLFLKFSLILCSFTELSCFWRMKNSEDSDGDLRSDCGFVLLTTKKNIEDFYNDINEVRIPARRYEFFLVMFFATDEINNNPYLLPNISLIFSIIAGLCEDTLGVLDEIYSQQNNSWNIVNYICEKGQRCDIELTGPSWKASVKLSIHSMIPSVRMCDTGCVFFGPFNPNLSDHDQFPYMYQIATKDTCLSHGMVSLILHFRWNWLGLVISDDDQGIQFLSDLREEMQSHGICLAFVNMIPETMQVYMIKAKIYDKQIMTSSAKVVIIYGEMNSTLEVSFRRWSYLGVQRIWITTSQWDVITIKKDFNLDFFHGTLTFAHHKVEVAKFRNFMQTRNPAKYPVKFFESVLGWNYFNCSISKNSNLMDHFIFNNTLEWIALNKYDMVLSEEGYNLYNAVYAVAHTYHELILQQTESQNIAEPNGVFIDCQQVASLLKTRVFTNPVGELVNMKHREKQCVEYDIFITWNFPEGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTSVPSSMCSATCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDMYANLEQTQCLQRTVSFLAYDDPLGIALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTTPGRRLRGMMITWASNFVIPFCTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTIIICNKGSVIAFHVVLGYLGSLALGSFTIAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVVVEVFSILASSADLLGCIFVQKCYIILVSSNSNFLHK", "length": 849 }, "evidence": [ { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A741-1", "protein_name": "Vomeronasal 2 receptor, 10", "gene_name": "Vom2r10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMFSWIFIFWLLQILKFVSAIVFNISRCYYIITEEFHHEGDIVIGAFFPLHTFYTGKKMPDPTLPYQYLDNYIQYNFRNYQYILALLFAIEEINGNPNLLPNISLGFDFYNVRFTEKETLMNAVIWLTAHVQRKVLPNYNCKKKKFSAALTGTSWTTSAQIGTLLQLFKFPQITFGPYDPLLSDHGQYSSLYQMAPKDTSLSLAIVSLMVYFRWSWVGLILPDDHKGNKILSDYREEMERQRVCIAFVKMIPATWTSYFPRFWENMNETNVIIIHGDIDSLESLLRNIGQRLLTRNVWVMNIERHVTEFSDYFMLDSFHGSLIFKHNYREKFEFTKFIQTVNPNRYPEDIYLPKLWNLLFKCSFSDRNCQVLDNCQTNASLDILPSHIFDVAMSEESISIYNGVYAVAHSLHDMRLHQVQMRPYENGEGMIFIPWQLNTFLKDLEVRDNRSLNWIQTIDAEYDILNLWNLPKGLGLKVKIGSFSANAPKGQQLSLSEQIIQWPEIFSKVPQSVCSESCGPGFRKVTLEGKPICCYKCTPCAENEISNETDSDQCVRCPESHYPNTEKSNCYQKTSSFLAFEEPLGMALASIALCLSALTAFVIGIFVKYRDTPIVKANNQALSYILLITLKFCFLCSLNFIGQPNTAACILQQTTFGVAFTVALATVLAKAITVVLAFKVSFPGRMVRWLMISRGPYYIVPICTLIQLLLCGIWMTMSPPFIDQDPHTEHGHIIILCNKGSSLAFHAVLGYLCLLALGSYTMAFLSRNLPDTFNESKFLSLSMLVFFCVWVTFLPVYYSTKGKVMVAMEVFSILASSTALLAFIFGPKCYIILLRPDKNSFNHVRKKAHFRRKNSPKI", "length": 858 }, "evidence": [ { "id": "MGI:3761531", "url": "https://alliancegenome.org/gene/MGI:3761531#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PYF5-1", "protein_name": "Vomeronasal 2, receptor 17", "gene_name": "Vmn2r17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLCVFTISFLLMTFSLFLCSLTGPSCFWRIQNNEDNDGDLHRDCGFFLFTSEEPIKEDFYHFCIDFRIPARRYEVFLVMFFATDEINRNPYLLPNMSLIFCLIVGMCGDTLGYLEETHSPNNTWNSINYNCEIRPICDIELTGPSWTTSVKLAINSRKPKVFFGPFNSHLSDHDQFPYIYQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQSIQFLSDLREAMQRHGICLAFVNMIPENMQIYMTRGKIYDKQIMTSSAKVVIIYGEMNSTLEVSFRRWAYLCARRIWITTSQWDVITNKRDFSFDFFHGTVTFAHHNGEIVIFRNFLQTVNTSKYPLDISQTMQEWNYFNCSISKNSNSKMDHFTFNNTLEWTALQKLNMVLSEEGYNLYNAVYAVAHTYHELILQQVEFQKMAEPKGIFTDCQQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFNIWNFPQGLGLRVKIGSYYPCFPQNQQLHISEDLEWATGGTSVPTSMCSVTCTAGFRKIHQKQTADCCFDCAHCPENEVSNETADMEQCVRCPDDKYANLEQTHCLQRAVSFLAYEDPLGMALGCMALCFSALTLLVFFTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTAPGRRVRGMLVAGAPNLAIPICTLIQIVLCGIWLVTSPPFIGRDTKSEHGKTILICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLMFCSVWITFLPVYHSTRGKAMVVVEVFSILASSAALLGFIFVPKCYVILVKSDSNFREKYKNKFHY", "length": 849 }, "evidence": [ { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PZA6-1", "protein_name": "Vomeronasal 2, receptor 113", "gene_name": "Vmn2r113", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLILLFLLLNIPLIVADFIDPRCFWRIKQNKDEDGNLGSGCSFFIQAVQWPVEKEYFSSILNTQTHTENHKYALVLAFSINEVNRNSDLLPNMSLIFTFSALICDYESQLKSLIHLSLQNHEIFPNYICNDDVCAVALTGLNWTTTLTLYTILNNFISHQFLHLTYGPFHPVLSDHEEFPYLYQMASEDTSLALAMVSFIIHFSWNWVGLAISDNDKGIQFLSYLRREMEKNTVCFAFVSMIPVNMHLYMTRTEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLDIKRIWVTTSQWAITTGKKDFTFNNLYGTFAFGHHHGEISGFKNFVQTLNLLKYSDEYLVKLEWMYFNCEVSAPKCKTLKNCSSNHPLEWLMVRTFDMAFTEGSYAIYNAVYAVAHALHELTFQKFDNLPTDNVKEQNYACNKLGSFLRKIHFTNPVEDRVNMNQRNKLQENYDIFYVWNFPQGLGLKVKIGIFSPYIINGQQLHLSEDMLEWARGSTQMLTSVCSADCGPGFRKFGKNGMPACCFDCSPCPENEISNETNVELCVPCPEDQYANTEQNHCIHKALIFLTYKDPLGMALSLMALCFSAFTAVVLLVFVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCILQQVTFGVAFTVAVSTVLAKTITILLAFRVTAPQRMMKYFLVSGTYIYIIPICTLIQVIVCAVWLGAAPPSVDIDARSEHGHIIIVCNKGSVSAFYCVLGYLACLAFGSFTLAFLSRNLPSTFNEAKSITFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSTLASGAGMLICIFVPKCYIILFMPDRNSLQMIRKKSSSHAHLS", "length": 856 }, "evidence": [ { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PZX4-1", "protein_name": "Vomeronasal 2, receptor 87", "gene_name": "Vmn2r87", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMCVLTTSFLFLKFSLILCCLTEPICFWRIKDSEYNDGELQSECGFFLWTMEKPMEDDFYNVRFDFRIPASEYEFVLVMFFATDEINKNPDLLPNTSLVFSVIGGKCQDSLGLLGEEYILINDSLNYVNYVCKADDTCVIDLTGPSWKTSLKLAIDSWTPKVFFGPFNPNLSDHDRFPYVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGARRIWITTSQWDVITNKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSVLRWNYFNCSVSKNSIKMDHFTCKNPLEWTALHNYDMALSDEGYNLYNAVYAVAHAYHEHILHQVESQKMAEDKGKYTECQQLAPLLKTRVFTNPVGELVNMNQREYQCAEYDIFIIWNFPQGLGLKVKIGNYFPCFPRSQQLHISEDLEWVTGGTLVPSSMCSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEQSHCLQRTVSFLAYEDPLGMVLGSMALSSSAITILVLVTFMKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIEHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGKRMRGMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIDRDIQSEHGKTVIFCNKGSVIAFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKIMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSNFIQKYKGKLLY", "length": 848 }, "evidence": [ { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0E7-1", "protein_name": "Vomeronasal 2, receptor 115", "gene_name": "Vmn2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLLADFISPRCFWKMKQNENRDRNQGTGCTFMIHAVQRPVEKEYFSHILNIQTHTENHKYALALAFSIYEINMNPDILPNMSLIFEFSVHNCVWESKLMSFMHVSLQNYDIFPNYLCKEYTKCAMALTSLNWATTVKFNTILNNFISQQFFQITYGPFHPVLSDHEKFPYLHQMASDHTSLAFGLVSFIIHFGWNWVGLVISDNDQGIQFLSYLKTEMEKNTICFAFVNMIPMSMNLYMSKAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWNVSPGMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQITFQKFDNLPKDNGKEHNYSCKKLYSFLRKTQFINPVGDRVNMNQRDKLQEEYDIFYIWNFPHGLGFKVKIGIFSPYFPNGQQVHLSEDMIEWAKGSAQMPTSVCSADCGPGSRKFRMDGMAACCFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNHCIRKIVVFLSYEEPLGVALSLISLFFSAFTIVVLGVIVKHHSTPVVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGIVFTVSVSTVLAKTITVVLAFKIIASQRMMKYFLVSGAINYIIPVCILIQVIVCAVWLGASPPSVDIDGQSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVPKCYTILFRPDQNSLEMIRVKSSSNARSS", "length": 857 }, "evidence": [ { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C1-1", "protein_name": "Vomeronasal 2, receptor 118", "gene_name": "Vmn2r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMFTSIFIVLLLKLPLLLCNSAENMCFWRVKLNENCDGDLPQDCAFLLYTQVDPAPKDFLKYLFKSCLPSKIHQYLLSLYFAMEEINSNPYLLPNVSLGIEYFKGKCNGYLSLFTNLNIMTKYYHTFPNYICDPGACEIALTGPLWISSAQVATILQLKFIPQVRQITYGPFYPLLSDQSKFPNLHQIAPKNRFLPEAIVSLLFHFSWIWVGLVIQDDDQGIQFLLDIKEEMQRNGVCLAFVNVIPQNMHLFTTRAEKYYNQIITSSANVVILYGELNTALEVSFKHWKYLGTQKIWFTTSQWDAITREKDFSLTSFYGTLTISQYHGDVSTLNNFFQGANLSKDTHYFSSERLGWMYFNCSILKSNCKTPNQCTSSNLLEWLPRHSFDMAMNDESYNIYNAIYAVAHALHEMVLQKIDFQQLENVTQLMQECVQIHAFLENMQFLNPIGDVVIINQQAKTDAEYEIYMIWNFPQGLGVKVKIGRFYSYFLHDQKLYLYEDMIQWASGYSQIPPSVCSVSCAPGFKKFYLEEKPSCCFDCSPCPENEISNATDLTQCVKCPDGQYANIERNHCFPKVVTYLAYADPLGIVLACMALFLSMLSVLVLGIFVKNQYTPIVKANNRTLSYILLISLTLCFLCSLFFIGHPSTARCLLQQITFGILFTVAVSAVLAKTITVLLAFSITIPGRRVKWLLLFGTHKVIIPICSLFQLIICGFWLGLSPPFVERDTHTEHGHIIIMCNKGSLIAFYSVLGYLGCLALASFIMAFLVRNLPDTFNEAKFLTFSMLVFCSVWVTFLPVHHSTKGKAMVAVEVFSILASSAGLLGCIFIPKCYIIVLRPDRNFIQRSKGKNHS", "length": 853 }, "evidence": [ { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4X4-1", "protein_name": "Vomeronasal 2, receptor 11", "gene_name": "Vmn2r11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLRTFTISFWLLKFSLILCHVTEPICFWRIKNNKDNDGDLRSDCNYFLWTFEETTEINFYNIVDFRIPTRRYEFFLVLFFATDEINKNPDLLPNISLIFWLFGGQCEDEWGVLDTNYSQNNINVKFINYDCLSPNCYIDLTGPSWKTSLKLPNILTIIVLMWMSHPLFYILQVFFGSFNPNLSDHDQFPYVHQVATKDTLLSHAMVSLMLHFRWTWIGMVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPENMQIYMTRAKIYDKQIMESTAKVAIIYGEMNSSLEVSFRRWEDLGVRRIWITTSQWDVITNKNDFSLDFFHGTVTFEHHHSEIAKFKNFMQTINTDKYPVNISESILGWNYFNCSTSMNSYSKMDHLTFNNTSEWTALHKYDMALSEEGYNLYNAVYAVAHTYHELILLQVESQQMAVPKGTFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFSQGLGLKVKIGSYLHCYPRSQQLHISEDLEWVTGGSSVPSSMCSMTCTAGFRKIHQNETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGIALGCMALFLSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNLVIPICTLIQLVFCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILVRLDSNFLQKYEHKLPS", "length": 861 }, "evidence": [ { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6I0-1", "protein_name": "Vomeronasal type-2 receptor 116", "gene_name": "Vmn2r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFLFLNIPLLVADFISPRCFWKMKQNEYRDRHHGTGCIFLILAIQQPVKKEYFSHILNIQTHTENHKYALALAFSIYEINRNPDLLPNMSLIFIFSADSCEWESELSLIRFGLQNSDNLPNYLCEELTKCILALTNMNWATTVTLHTILSNFLSDQLLHITYGTFHPALSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTLCFAFVNMIPLNINLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNKYGTFAFEQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLKWLMVHTFDMAFIEESYYIYNAVYAFAHVLHQFTFQKFDNLPKDNGKEHNYSCKKLYSYLRKNHFINPVGDRVSMNQRDKLQEEYDIVYIWNFPQGLGLRVKIGMFSPYFPNGQQVHLSEDMLKWARGSTQVPTSMCSADCGPGSRKFRMDGMAACCFHCKPCPENEISNETNVDNCVQCPEDQYANTEQNHCIRKAVVFLSYEEPLGVALSLLSLCFSAFTTVVLGIFVKHHNTPIVKANNRTLTYLLLISLIFCFLCPLLFIGHPNSATCILQQLTFGVVFTVSLSTVLAKTITVVLAFKIIASQRMMKYFLISGAINYIIPICILIQVIVCAVWLRASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLAILAFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVPKCYTILFRQDQNSLEMIRVKSSSNVHVS", "length": 856 }, "evidence": [ { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q759-1", "protein_name": "Vomeronasal 2, receptor 14", "gene_name": "Vmn2r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNLRGFGLSFMLLKFSLIWCHLTEPICFWRIKNNEDNDGDLRSDCGFFLAAVEGPIDHTYNISDFRIPARRHEFFLVLFFATDEINKNPYLLPNMSLIFPEDPGQCEKLLGELDKIHSEAKFTVDFTDYICAGYGTCYIGLIGPSWKTSVKLSTNSGTPRVFFGPFNPKLSDHDQFPYVHQVATKDTHLSHGMITLMLHFRWTWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPEDMQLYMTRAKIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGARRIWITTSQWDVITNKNDFSLDFFHGTVTFEYHHSEIAKFKNFMKTMNTDKYPVNISESILRWNYFNCSTSMNSYSKMGHFTFNNTLEWTALHNFDMALSEEGYNLYNAVYAVAHTYHELILLQVESQQTEEPKGTFTDCQQVSSTLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGSYLPCFPQSQQLHISEDLDWATGGSSVPSSLCSVTCTAGFRKIHQKQTADCCFDCDQCPENAVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCMALTFSALTVLVLVTFVKYKDTPIVKANNRILSNILLISLVFCFLCPLLFIGHPNKATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTSPGGKMRGMLASGAPNLVIPICTLVQLVLCGIWLVTSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFVPKCFVILVRPDSNFLQKYKDKLFY", "length": 848 }, "evidence": [ { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LNQ1-1", "protein_name": "Vomeronasal 2 receptor, 68", "gene_name": "Vom2r68", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKELCTFTISFLLLKFSFIMWGLTEPSCFWRIKNNGDNDGDLRTDCGFVLFTRQEPIEENFYNEIVYFRIPARSYEFFLVMFFATDEINKNPYLLPNMSLIFSLIVGMCEDTLEYVDTNYSFKRNTLNIVNYNCYLRARCYIQLTGPSWKTSLKLTINSRKPKVFFGPFNPNLSDRDQFPYVNQIARKDTFLSHAMISLMLFFEWTWIGLAISDDDQGIQFLSVTREVMQKHSICSAFVNVIPENMQIYMARANIYDKQIMTSSAKVVIIYGERNSTLEVSFRRWEYLGAQKIWITTSQWDVITNKRVFSLDFFHGTVTFAYHNGRIPKFRNFMQTMNTSKYPVDISQTILEWNYFNCSIFKNSDSEMNHFTSKNTEEWLAQHKFDMVLSEEGYNLYNAVYAVAHTYHELILQEVESQKILRHKGRFINCQQVASLLKTRIFMNPVGELVNMNQRENQCAEYDIFNIWNFPQGLGLKVKIGSYFSCFPQSQQLQISEDLKWATGGTSVPTSMCSVTCTAGFRKIHQNEAAHCCFDCALCPENEVSNDTDMEQCVRCPDDKYANLEQTYCIQRHVSFLAYEEPLGLTLGCMALCFSALTILVLVTFVKHKNIPVVKANNCILSYILLISLIFCFLCSLLFIGHPKKTTCILQQITFGIFFTMAISTVLAKTITVVMAFKLTTPGRRMRRILASGAPNLIIPICTLIQLVICGTWLATSPPFIDRDIQSEHGKVIIICNKGSVTAFHFVLGYLRSLALGSFAVAFLARNLPDRFNETKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCVFIPKCYVILVRPNSNFLQKYKNKLLY", "length": 849 }, "evidence": [ { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3UW56-1", "protein_name": "Vomeronasal 2, receptor 85", "gene_name": "Vmn2r85", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMCSLTMSFLFLKFSLILCCLTEPICFWRIKSSEYNDENLQSECGYFLWTMKKLMKDDFYNVRLDFRMPAREYEFVLVMFFATDEINKNPDLLPNTSLVFSVMADKCQDSLGILDLKYMLVNDTLNYVNYVCEADDSCAIGLTGPSWKASLKLAIDTWAPKVFFGPFNPNLSDHDRFPNVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGVQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGAQRIWITTSQWDVITNKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPISISESILRWNYLNCSVSKNSIKMDHFTCKNPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILQQVESQKMVEDKGKYTECQQLAPLLKTRVFTNPVGELVDMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTSVPSSMCSVTCTAGFRKIHQKETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANIEQTHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGRRMRGMMMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIERDIQSEHGKTVIFCNTGSVLSFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSHFIQKYKGKLHY", "length": 850 }, "evidence": [ { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8Y4-1", "protein_name": "Vomeronasal 2, receptor 86", "gene_name": "Vmn2r86", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMCALTISFLLLKFSLLLCCLKEPICFWRIKSSEYNDGDLQSECGYFLWTMKKLMKDDFYNVRLDFRIPASEYEFVLVMFFATDEINKNPDLLPNTSLVFSVMAGKCQDSLGNLDIQYMLINDSLNYVNYVCDIDDSCAIGLTGPSWKTSLKLAIDSWTPTVFFGPFNPNLSDHDRFPNVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGARRIWITTSQWDVITNKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSILRWNYFNCSVSKNSIKMDHFTCKNPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILHQVESQKMVEDKGKYTECQQLALLLKTRVFTNPVGEMVNMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPWSQQLHISEDLEWATGGTSVPSSICSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETVDMEQCVRCPDDKYANLEQMHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGKRMRGMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIERDIQSEHGKTVIFCNKGSVLSFHVVLGYLGSLALGSFIVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSNYIQKFKGKLLY", "length": 848 }, "evidence": [ { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N5U4-1", "protein_name": "Predicted gene 14496", "gene_name": "Gm14496", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKQLCAFTISFLLLKFSLILCCLTEPICFWRIKNSEDDDRDLQRECHFYLWAIDKPIEDDFYNIVYNFRIAASEYEILLIMFFATDEINKNPYLLPNITLIFTIIGGHCHDLLGGLDEAYTQINGRVKFVNYFCYSDDSCLIGLTGPSWKTSLKLAMDSSMPMVFFGPFNPNLCDHDRLPHVHQVAPKDSHLSHGMVSLMFHFTWTWIGLVISDDNQGIQFLSDLRKEMQRHGICLAFVNMIPENMQIYMTRATIYDKQIMTSSAKVVIIYGDMNSTLEISFRRWEDLGAQRIWITTSQWDVITNKKDFTLNLFHGTVTFAHYKGEIPKFRNFMQTINTDKYPVDISHTILEWNYFNCSSSKNSSKMDHFTFNNTLEWTALHKYDMALSEEGYNLYNAVYAAAHTYHEHFLQQAESQKRADPKRDFTECQQVSSLLKTRVFTNPVGELVNMMHGENECTEYDIFIIWNFPQGLGLKVKIGSYLPCFPQSQQLHISDDLEWAMGGTSVPSSMCSMTCTAGFRKIHQKETADCCFNCVPCPENEVSNETADMEQCVMCPDDKYANIEQTHCLQRTVSFLAYEDPLGMALGCMALSFSAITTLVLVTFVKYKDTPIVKANNRILSYILLISLDFCFLCSLLFIGHPTQVTCILQQTTFGVFFTVAVSTVLAKTITVVMAFKLTTPGRRMRGMMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIKSEHGKTVILCNKGSVIAFHFVLGYLGFLALGSFTVAFLARNLPDRFNEAKFLTFSMLMFCSVWITFLPVYHSTRGKVMVAVEVFSILASCAGLVGCIFFPKCYVILIRSDSIFIQKYKDELHY", "length": 849 }, "evidence": [ { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N621-1", "protein_name": "Vomeronasal 2, receptor 10", "gene_name": "Vmn2r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNLCVFTLSFFLLEFSLILCHLTEPICFWRINNNEDNDGDLRSDCGFFLAAVEGPTDDSYNISDLRIPARRYEFFLVMFFATDEINKNPYLLPNMSLIFPINHGQCEKTLGDLDKIYSEKNYTVEFTDYICVSFGTCFIALIGPSWKTSIKLSINSGTPRVFFGPFNPKLSDHDQFPYVHQVATKDTRLSHAMVSLMFHFTWIWIGMVISDDDQSIQFLSDMREEMQRHGICLAFVNMIPEDMQLYMTRATIYDKQIMESTAKVVMIYGEMNSTLEVSFRRWEDLSIRRIWITTSQWDVITNKNDFSLDFFQGTVTFAHHVGEIANFRNFLQTMNSEKYTVNISESRLGWNYFNCSISKNSNKKDHFTFNNTLEWTTLHKYDMVLSEEGYNLYNAVYAVAHTYHELVLQQVESQQMTVPKGTFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYLPCFQQSQQLHISEDLEWATGGSSVPPSLCSVTCTAGFRKIHQKQTADCCFDCDQCPENAVSNETVDMEQCMRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCTALSFSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNIVIPICTLIQLVLCGIWLVTSPPFIDRDMQSEHGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTQGTVMVVVEVFSILASSAGLLGCIFLPKCCVLLRIQNSNFLHKYKHELHS", "length": 847 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N674-1", "protein_name": "Vomeronasal 2, receptor 111", "gene_name": "Vmn2r111", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFLLLNIPLLVADFIHPRCFWKMKRNENKDRNQGTGCTFVIHAVQQPVEKEYFSHILNIQTQTENRKYALALAFSINEINRNPDLLPNMSLIFKFSAHNCVWESEIMNLMLLSLQNYDIFPNYLCKEYTKCAMALTNLNWATTVTLYTILNNIISEQFLQITYGPFHPVLSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTVCFAFVNMIPVNMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPRMKDFTFGNKYGTFDFQQHNSEISGFKNFVQTLNSVKYPDDYLVELEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEKSYYIYNAVYAFAHALHQFTFQKFDNLPKDNGKEHNYSCKKVDPSLRKMQFTNPVGDIVNMNQRDKLQEEYDIFYIWNFPQGLGLRVKIGMFSPYLPNGQQVHLSEVIIKWTKGSTQVPTSVCSADCGPGSRKFGMDGMAACCFHCKPCPENEISNETNVDNCAQCPEDQYANTEQNHCIHKAVVFLNYEEPLGMALSLFSLCFSAFTTVILGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCILQQITFGVVFTVALSTVLAKTIVVVLAFKITASQRMMKYFLVSGASNYIILICTLIQVIVCAVWLGASPPSVDIDAQSEHGHIIIVCHKGSVNAFYSILGYLALLSFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVSKCYTILFRPDRNSVEMTRVKSSFHARVS", "length": 857 }, "evidence": [ { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z8-1", "protein_name": "Vomeronasal 2, receptor 9", "gene_name": "Vmn2r9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLRTFTISFWLLKFSLIFCHVTEPICFWRIKNNEENDGDLRSDCNFFLWTYDESTEINFYNIVDFRIPARRYEFFLVLFFATDEINKNPDLLPNMSLIVWLLGGQCGDEWSVLYKNYSQENINVEFINYDCLSPDCYIHLTGPSWKTSLKMSIQSRTPKLFFGPFNPNLSDHDQFPYVHQVATKDTHLSHAMVSLMLHFRWAWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPKDMQIYMTRATIHDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGARRIWITTSQWDVITNKNDFSLDFFHGTVTFEHHHSEIAKFKNFMKTMNTDKYPVNISQSIGGWNYFNCSTSMNSYSKMDHLTFNNTSEWTALHNFDIVLSEEGYNLYNAVYAVAHTYHELILLQVESQQTEVRKGIFNDCQQVSSMLKSRIFTNPVGELVNMKHRENQCAEYDIFIIWNFPQGLGLKVKIGSYLPCFQQSQQLHISEDLDWATEGTSVPSSMCSVTCTAGFRKIHQNETADCCFDCDRCPENEVSNETADMEQCVSCTGDKYANLEKTHCLQRAVSFLAYEDPLGMSLGCIALFLSALTSLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNLVIPICTLIQLVFCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCAILVRLDSNFLQKYKDKLPS", "length": 848 }, "evidence": [ { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N789-1", "protein_name": "Vomeronasal 2, receptor 124", "gene_name": "Vmn2r124", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMFSWIFILWLLQISKFVSAFILNISRCYYIITEEFHHEGDVVIGAFFPLHTYYTGKKMPHPTVPYLYLDNYIQYNFKNYQYILTLLFAIEEINRNPNLLPNISLGFDFYNVRFTEKETLDNAVIWLSALVQRKFLPNYNCKKRNFTAALTGTTWKTSAQIGTLLQLFKFPQITFGPYDPLLNDHSQYSSLYQMAPKDTSLSLAIVSLMVHFRWSWVGLILPDDHKGNKILSDFREEMERKGICIAFVKMIPETWNLYFAKFWENMDETNVIIIYGDSDTLEGLMRNIGQRLFTWKVWIMNIEYNVFDRADYFMLDSFHGSLIFKHNYRENFEFTKFIQTVNPNKYPEDIYLPKLWHLFFKCSFADISCHALDNCQTNASLDLLPSHIFGVAMNEESTNIYNGVYALAHSLHEMRLQQLQMQPYLNGEGMVFFPWQLNTFLKDIEVRNNRSLDWRQTIHAEYNILNLWNLPKGLGLKVKIGSFSANAPQGQQLFLSEQMIQWPEIFSEIPQSACSESCGPGFRKVTLEGKAICCYKCTPCADNEISNESDVDQCVKCPEGHYANTEKNNCLEKSVSFLAYEDPLGMALASIALCLSALTIFVIGIFVKHRDTPIVKANNRTLSYILLITLTFCFLCSLNFIGQPNTAACILQQTTFAVAFTVALATVLAKTITVVLAFKVSFPGRMIRWLMISRGPNYIIPICTLIQLLLCGIWMATSPPFIDQDAHSEYGHIIILCNKGSAVAFHSVLGYLCFLALVSYTMAFLSRNLPDTFNESKFLSFSMLVFFCVWVTFLPVYHSTKGKVMVAMEVFCILASSTALFAFIFGPKCYIILLRPEKNSFRHTRKKTHIPVPKL", "length": 855 }, "evidence": [ { "id": "MGI:3761531", "url": "https://alliancegenome.org/gene/MGI:3761531#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X2-1", "protein_name": "Vomeronasal 2, receptor 13", "gene_name": "Vmn2r13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKELCVFILCFLLLKFSLILCHLTEPICFWRIKSNEDNDGDLRSDCGFFLAAVEGPIDQIYNISDFRIPARRYEFFLVLFFATDEINKNPYLLPNMSLISPITSGQCEKTLGDLDKIYSEKNITVEFTDNICVFYGACYISFIGPSWKTSVKLSIHTGTPRVFFGPFNPKLSDHDQFPYVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQFLSDMREEMQRDGICLAFVNMIPGNMQLYMTRAKIYDKQIMESTAKVVIIYGEMNSTLEVGFRRWIHLGVRKIWITTSQWDVVTNKKDFSFNFFHGTVTFAHHIGELVKFRNFLQTMNNEKYPVNISETRLGWNSFNCSISKNSNKKDHFTFNNTLEWTARNNFDMVLSEEGYNLYNAVYAVAHTYHELILQQVESQQMAVPKGIFTDCQQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFIIWNFPKGLGLKVKIGSYLPCFHQSQQLHISEDLEWATGGTSVPSSMCSVTCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANVEKTHCLQRVVSFLAYEDPLGMALGCMALSFSALTVLILVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQITFGVFFTVAISTVLAKTITVVLAFKLTTPGRRMRGMLASGAPNLAIPICTLIQLVLSGIWLVKSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILD", "length": 831 }, "evidence": [ { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N217-1", "protein_name": "Vomeronasal 2, receptor 12", "gene_name": "Vmn2r12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLCVFILFFMLLKFSLISHHLTEPICFWRIKNNEDNDGDLRSDCGFFLAAVEGPIDQIYNISNFRIPARRYEFFLVLFFATDEINKNPYLLPNMSLISPIASGQCEKTLENLDKIYSEKNHTVQFTDNICVFYETCYISLIGPSWKTSVKLSIHHGTPRVFFGPFNPKLSNHDLFPNVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQCIQFLSDLREEMQGHGICLAFVNMIPEDMQLYMTRAEIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDKGVRRIWIATLQWDVITNKKDFTLDFFQGTVTFAHHVGDIANFRNFLQTMNNEKYPINISESILQWNSFNCSFSKNSNKKDHFTFNNTLEWTALHIYNMVLSEEGYNLYNAVYAVAHTYHELILQQVESQQTEVPKGTFTDCQQVSSMLKSRIFTNPFGELVNMKHQESQCADYDIFIIWNFPKGLGLKVKIGYYLPCYQRSQQLHIYDLEWATGGTLVPSSMCSVACTAGFRKIHRKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCMALFLSALMVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCPLLFIGHPNLATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNLVIPICTLIQLVLCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVYCSVWITFLPVYHSTRGAVMVVVEVFSILASSAGLLGCIFLPKCCVILLD", "length": 831 }, "evidence": [ { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N221-1", "protein_name": "Vomeronasal 2, receptor 112", "gene_name": "Vmn2r112", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFLLLNIPLHVADFIHPRCFWKMKRNENKDRNQGTECTFVIQAVQQPVEKEYFSHILNIQTQTENRKYALALAFSINEINRNPDLLPNMSLIFKFSAENCVWENKLMSLMHSSLQNYDILPNYLCEEYTECVMALTSLNWATTVTLYTILNNFMSEQFLQITYGPFHPVLSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTVCFAFVNMIPVNMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNKYGTFDFQQHNSEISGFKNFVQTLNSVKCPDEYLVELEWMHFNCEVSASKCKPLKNCSSSYSFDWLMEHTFDMAFIEKSYYIYNAVYAFAHALHQFTFQKFDNLPKDNGKKHNYSCKKVDSSLRKTQFTNPVGDIVNMNQKGELQEEYDIFYIWNFPQGLGLRIKIGMFSPYFPNGQQVHLSEVMIRWAKGSTQVPTSVCSADCGPGSRKFEMDGMAACCFHCKPCPENEISNETNVDNCVQCPEDQYANTEQNHCIHKAVVFLSYEEPLGMALSLLSLFFSAFTTVILGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCFLQQITFGVVFTVALSTVLAKTITVVLAFKITASQRMMKYFLVSGASNYIILICTLIQVIVCAVWLGASPPFVDIDAQSEHGHIIIVCHKGSVNAFYSILGYLALLSFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGILGCIFVSKCYTILFRPDRNSVEMTRVKSSFHAHIS", "length": 857 }, "evidence": [ { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A0-1", "protein_name": "Vomeronasal 2, receptor 15", "gene_name": "Vmn2r15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLRVFTFSLLLLKCFLISCHLTEPICFWRLKNNEDNDGDLRSDCGVFLAAVEGPIDQIYNISDFRIPARRYEFFLVMFFATDEINKNPYLLPNMSLISPVDHGQCEETLGLLDEIYLEKNNSVEFTDYICVFYGTCYIGLIGPSWKTSVKLSIHSRTPRVRMCETRLVFFGPFNPNLSDHDQFPYVHQVAIKDTHLSHGMASLMLHFRWTWIGLVISDDDQSIQFLSDLREEMQRHGICLAFVNMIPEDMQLYMTRAKIYDEEIMTSTAKVVIIYGEMNSTLQVSFRRWEDLGVRRIWITTSQWDVITNKNDFSLDFFHGTVTFAHHVGKIAKFRNFLQTMNSDKYPVNISKSILGWNYFNCSVSKKGNKKDHFTFNNTLEWTALHNFDIVLSEEGYNLYNAVYAVAHTYHELILQQVESQQTAVPKGIFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGNYLPCYPWSQQLHISENLEWATGGSSVPSSMCSVTCTAGFRKIHQKQTADCCFDCDQCPENEVSNETADMEQCVRCPDDKYANLEKTQCLQRVVSFLAYEDPLGMTLGCMALTFSALTVLVLVIFVKYKDTPIVKANNRIVSYILLISLVFCFLCSLLFIGHPTQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGGRMRGMLASGAPNLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILLRPDLTFLQKYKDKLPS", "length": 855 }, "evidence": [ { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N472-1", "protein_name": "Vomeronasal 2, receptor 8", "gene_name": "Vmn2r8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLRTFTISFLLLKFSLILCHVTDPICFWRIKNNEENDGDLRSDCNFLLWTDYESTEFNFYNIVDFRIPARRYEYFLVLFFATDEINKNPDLLPNMSLIVWLLSGQCGDEWSVLHKNYSQENINVKFINYDCLSPACYIDLTGPSWKTSLKMSIQSRTPKVFFGPFNPDLRDHDQFPFVHQVATKDTYLSHAMVSLMHHFRWMWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPENMQIYMTRATIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGVRRIWITTSQWDVITNKNDFSLDFFHGTVTFEHHHSEIAKFKNFMKTMNTDKYPVNISQSIVGWNYFNCSTSMNSFSKMDHLTFNNTLEWTALHNFDMVLSEEGYNLYNAVYAVAHTYHELILLQVESQQTEVPKGIFTDCQQVASMLKSRIFTNPIGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGSYLHCFSQSQQLHISEDLEWATGGTSVPSSLCSVTCTAGFRKIHQNETADCCFDCDQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPWGMALGCMALFLSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNLVIPICTLIQLFLCGIWLVTSPPFIDRETQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILVRLDSNFLQKYKDKLPS", "length": 848 }, "evidence": [ { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100721-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100721-9#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R9L8-1", "protein_name": "Vomeronasal 2 receptor, 77", "gene_name": "Vom2r77", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMFTSIFIVFLLKLPLLLSNSTENMCFWRANFNENCDGDLLHDCAFLIYTDEEPAPKDFFKYLFKLCLPSKIYQYVLSLYFAIMEINGNPYILPNVSLEIAYFRGECNGYLSLLTNLNIMTKYQHTLPNYVCNPGACEIVLTGPLWKSSAQVATILQLNFIPQITYGPFHPLLSDQIKFPNLHQIAPKDRFLCEAIVSLLFHFSWTWVGLVVEDNDQGIQFLLDIKGEMQRNGVCLAFVNVIPQNMQLFTTRAEIYYNKIITSSANVVIIYGEMNTALEVSFKHWKYLGTQKVWFTPSQWDVITREREFTSTSFHGTFTISQYHGDVSILNNFIYRMNLSKDTHYFSPERLGWMYSNCSLLKSNCKTPNQCTSSNSWEWLPWHSFDMAMNDECYNVYNAIYAVAHALHEMILQKIDFQQRNNVSQLMQECLKVHEFLQKMKFFNPVGDIVVINQRTKRDAEYEIHMVWNFPQGLGMKVKIGRFFSHFLHDQKLYLYEDMIQWALGYSQIPTSICSMSCAPGFKKSYPEEKASCCFACSPCPENEISNATDLAQCVKCPDGQYANIERNHCFPKAVTFLDYADPVGIVLVCMALCLSTLSALILGIFVKKQNTPIVKANNRTLSYILLVSLTLCFLCSLLFIGHPSTARCVLQQITFGTLFTVAVSTILAKTITVLLAFSITVPGRRVTWPLFVASKVIIPICSLFQLMLCGLWLGLSPPFVERDAHSEYGHIIIMCNKGSIIAFYCVLGYLGCLALASFIVAFLGRNLPDTFNEAKFLTFSMLVFCSVWVTFLPVFHSTKGKVMVAVEVFSILTSGAGLLGCIFIPKCYIIVLRQDRNFIKKVKGKNHS", "length": 849 }, "evidence": [ { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1LV89-1", "protein_name": "Olfactory receptor CQ3 precursor", "gene_name": "olfcq3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLNICLHLSFIFISVNSDSCQIQGHFKLNRMYKDGDYIIGGLFEVQHLKVFPELSFRMEPEQPKCEEFYMSSFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCLKLVVAFRAATTLISGTEETFSNFNCTGPPPVIAIVGDPGSTHSIAVSSVLGLFHVPLISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMVQILKYFGWTWVGVLYSDDDYGIYAAQSFQQEMQRFKGCVAFSEIVPYDNHRDIQRIVAVIKASTARVVVAFSTDLLPLMEELLQQNVTGRQWIASEAWSTSPVLHLPRFVPLVRGTLGIAIHRGKIKGLHEFLLHIQPDNDPTNNMVRIFWENMFGCSFEKGNGYGEKMCTAQEDLNITVNEYNDVSELRASYNVYKAVYALAHALHDLMQCEEGRGPFSGNSCADITKLKPWQMVPYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWHPSSDGLIVVRTVGVVDEGASAGRVLTLDEDAIYWNFETKKPPRSVCSESCPPGTRRAMRKGLPVCCFDCLPCADGEISNMSDATECTSCPNEFWSSPKKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVLAVFAHHHNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAMFGISFVLCVSSILVKTMVVIAVFKSSRPEGKSAVKWFGAVQQRGTVLVLTAVQIVICVVWLSTASPTPHKNILYVRSKIVFECSIGSMAGFAILLGYIGILAAVSFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFIPAYVSSPGKYSVAVEIFAILASSFGLLVAIFVPKCYIIILHPERNTKKAIMGRTAEK", "length": 855 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAH3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PAH3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAH3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 726, "end_pos": 728, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], 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This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323723.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323723" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAX6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ftr20", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAX6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-319", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-319", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19769", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19769", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "619192", "url": "https://www.ncbi.nlm.nih.gov/gene/619192", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:619192", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:619192", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PAX6", "url": "https://www.orthodb.org/?gene=A0A8M9PAX6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323723", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PAX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-319", "url": "https://zfin.org/ZDB-GENE-070912-319", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAEGRFSVDQNKFDCPICLDLLKEPVTIPCGHSYCMNCITDCWSQDEQRRVYSCPQCRQTFTPRPALNKNVVMAEMVENLKVTKVKTTDPAPSYAGPGDVECDVCTGIKYKAIKSCLLCLESYCQTHFERHEAFRTGKRHKITDASGRIQEMICLKHDKLLEVYCRTDQKCICLLCTMDEHKNHDTVSSSSERTEKQKHLEDTQRNLQQKIQEREKKIQVLKESLKTHKSSAQTAVEDSERTFTELIQSIERRRSEVTQMIRDREKTEVSLTEGLLKKLEQEIEDMKRRNTELEQLLHTDDHIHFLQRFQSLSKPLESTDLSSTAVSSGFRYEDVSKSVSQLKIKLEQICTEDIENIHGQARKMIFSALLSTSHTEPTTRKDFQQYFQQLSLDQNTAHQQICLTEDNTVATWTDRVQQYPDHPDRFDKFFGVLCRESVSGRCYWEVEWSGNERLYGVGVAVSYKTINRKGDMTTSGFGFNDQSWRLFSFKSRYTFLHDSKQTELSVVSRSSRIGVYVDHRAGILSFFSVSDTTMSLIHRVQTTFTQPLYPGFWINKGSRVKICHI", "length": 565, "header": "tr|A0A8M9PAX6-1|A0A8M9PAX6_DANRE Isoform 1 of Tripartite motif-containing protein 16 OS=Danio rerio OX=7955 GN=ftr20 PE=4 SV=2 CANONICAL=A0A8M9PAX6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PAX6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAX6/entry#A0A8M9PAX6-1", "sequence": { "sequence": "MAEGRFSVDQNKFDCPICLDLLKEPVTIPCGHSYCMNCITDCWSQDEQRRVYSCPQCRQTFTPRPALNKNVVMAEMVENLKVTKVKTTDPAPSYAGPGDVECDVCTGIKYKAIKSCLLCLESYCQTHFERHEAFRTGKRHKITDASGRIQEMICLKHDKLLEVYCRTDQKCICLLCTMDEHKNHDTVSSSSERTEKQKHLEDTQRNLQQKIQEREKKIQVLKESLKTHKSSAQTAVEDSERTFTELIQSIERRRSEVTQMIRDREKTEVSLTEGLLKKLEQEIEDMKRRNTELEQLLHTDDHIHFLQRFQSLSKPLESTDLSSTAVSSGFRYEDVSKSVSQLKIKLEQICTEDIENIHGQARKMIFSALLSTSHTEPTTRKDFQQYFQQLSLDQNTAHQQICLTEDNTVATWTDRVQQYPDHPDRFDKFFGVLCRESVSGRCYWEVEWSGNERLYGVGVAVSYKTINRKGDMTTSGFGFNDQSWRLFSFKSRYTFLHDSKQTELSVVSRSSRIGVYVDHRAGILSFFSVSDTTMSLIHRVQTTFTQPLYPGFWINKGSRVKICHI", "length": 565, "header": "tr|A0A8M9PAX6-1|A0A8M9PAX6_DANRE Isoform 1 of Tripartite motif-containing protein 16 OS=Danio rerio OX=7955 GN=ftr20 PE=4 SV=2 CANONICAL=A0A8M9PAX6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:619192", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:619192", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1REU8-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr65", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEFSVSVAQDQFSCAVCLDLLNDPVSIPCGHSYCMSCITDCWNKKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQEIHPGNQHQLTEATHRLKEMICPQHEKLLEIFCRTDHCCICYLCLVDQHKHHDTVSAAAERTELESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSITVSFPLDFDDIVKSVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTVNNWLVLSEGNTAVENKGSVQPYPDHPDRFDYWRQVLCRESVCGRSYWELEWSGARVFLSVSYKSIKRKGRGNECLFGRNAQSWSLSCSAESFSFRHNNKNTELPKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTNTLCPGFYVYKGSKVKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RFB3-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr14l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRSSTASQSRYGTQEKPRRSGRYSSSSSRSSSRDVLCDFCMIKKNKAVKSCLTCLTSFCEAHLQAHYEYPALMKHKLVAATGQLREKICGEHDKLLEVFCRSDQMCVCVLCIMEEHKKHDIVSAAAERTEKQKQLGAKLMTSQQKIEERMKKWQDLRQAVASLKHSSQSVLDENERIFAELLRALERRHGEVKEMIRAQEVLLLTNAERHLARLEEEITLLRKKHTDLEQLSQSDDHIHFLQSWQSLSAPSGYEDLSKVTLAPHHTFDNAKKAISDLKVQMEDISKEELNKISSAVNEVKILQTVDPAKREEFFEYSCQLSIDPLTAHPNLVLSDRNTVVQMSNEPRPYPDHPDRFDYWQQALCKPGLAGGRYYWELDWRGTEVDIAVTYKGIQRKGNDKPGSFGRNDKSWSLYCSESEYSFMHNSKSTAVSVPRSSRIGVYVDYESGTLAFYSVSDKMTLLYKVQTKFTEPLYPGIGVWGYGTTVRL", "length": 489 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RJY4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr03", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDSSKMAAESSVSFAQDQFNCSICLDLLKDPVAIPCGHSYCMSCISDYWDQDEWRGVYSCPQCRQTFTPRPALGKNTMLTEVVENIRKRKLQAGDVECDVCIGKAVKSCLVCLESYCQTHFEQHEEFHSRKRHKVTDANGRLQEMICPQHDRLLEMYCRTDQRCICMLCLMNEHKTHETVLPAEERAEKQKHFNEKLQQRIQEKQKQCEELRAAVESHKRSVQAAVEDTERIFTELIRSIERSRSKVTQLIRDQGKASVSGAEGRLEQLEQEINDLRRRNTELEQLSCTDNDIHFLQSFQSLSVPPASTDSSSISSRLSFNKFKMFVSRVKEELQNSLKDEKENISRIVRNISVLPTPEYERRKKFLQYYQQLTLDSNTAYKSLRLSEGNRVVTRMKKTSNHPDRFDGFAQLLCKESVRGRCYWEVERSGKGMYVSVSYKSIRRKGQGSECKFGCNDQSWSLYCSDTKCSFRHNNEESKLPVVSSSSRIGVYVDHSAGTLSFYSVSDTMSLIHRVHTTFTQPLYPGFGVSNESQVKLCDQA", "length": 542 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RKP5-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr76", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSESSSSECVDQFSCSVCLDLLKEPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCRESFSQRPLLKKNTLIAEMMETLQKTTLQTPAAAATAVDCDVCTTEKNRAVKSCLQCLASFCQTHLQLHYESPAFMKHKLVDASRHIQENICPSHGRPLEIYCQDDHQCICCLCIINSHKTHSVVSVDSEWINKKKELEKIAVERLKLIENREKGLWELSEAVKSFKSSADEAVEKMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIHKLLTTEDQIHCLKSCESVCVLPTFEEVPFSPHSHLSFKDLSISAFREALEDACRQQTDAISREVSNVHTVKPSEPKTYNDFLQYFYQPHLDPNTAHKNLILSEENRRISYSDTDQQYPDHPERFAAYCNVLCKEGLTGRCYWEVNCHGKIWAVAVCYKGISRKGNTDDNILGYNKQSWRLSRYQKNIFFVHNSEEVSIPVFHSSRIGVYLDHRAGILSFYSVSKTMTLIHKVQTTFTELLYPAFGLGECSIRIIKQKRFLKDQK", "length": 553 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RLP4-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25 isoform X1", "gene_name": "ftr02", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAQDQFNCSICLDLLKDPVAIPCGHSYCMCCISGYWDQDEQKGVYSCPQCRQTFTPRPALGKNTMLVEVVEKLRKRKLQAARPAQCYSESADVECDVCTGDKNKATKSCLMCLNSYCQNHLEQHETFFKIKRHNLMDATGRLQEMICPQHEKLLGIFCRTDKRCICYLCTMDEHKTHDTVSAAAERTDKQKYFEETLKKRIMENQKEREELRAALESHKRSVQATVEDTERIFTELICSIERTRSEVTQVIRDQEKAAVSGAERRLKKLEQEIDDLKRRNTELEQISNTDNHIHFLQNFQSFSVPPESTDTSIRSRLSFDDLVTFVSQVKEKLQQTVKQEQKNIFHIVRHINVMPSPQNKSRNDFLQYYKRFTLASNTAHESLKLSEGNRVVTRAKNALFSFPDIFEDLTQVLCNESVSGCCYWEVEWSGRGMCASVAYKSISRKGPGYDCRFGHNDQSWGLYFSDFSCSFWHNNIHTKLPGVSSSSRIGVYVDHSTGTLSFYSVSGRMRLIHRVYTTFTQPLYPGFGVCHDSQLKLCD", "length": 546 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RLR7-1", "protein_name": "Tripartite motif-containing protein 16 isoform X1", "gene_name": "ftr33", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSKMAESSVSLAHREFSCSVCLDLLKDPVAIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQQLNPGNRHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISRRVSSISIIPAPEPQTREQFLQYSQQFTLDPNTAHTYLVLSEGNTAVENKGSVQPYPDHPDRFDCWRQVLCRESVCGRSYWELEWSGVDVLISVSYKSISRKGSGNECLFGLNDQSWSLCCSADSFSFRHNNINTDLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFWVCSRLKLCDLTV", "length": 561 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RN91-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr36", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFCPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQELNPGNQHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTELESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTANNRLILSEGNTVVDCKGSVQPYPDHPDRFDGWFQVLCKESVCRRSYWELEWSGNGVEIAVSYKSISRKGSILECRFGLNDQSWSLFCSVHSFSFWHNNKQTQLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHALYPGLCLYSRVKLCDLTV", "length": 556 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2B8U3-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr57", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEVRFSLEEFMCPVCLDLLKDPVTIPCGHSYCKTCITGCWDQEDDKRVYSCSQCREAFNPRPALAKNTILAEMVEKLKTKPPADCYAGAGDVQCDVCTGIKYKAIKSCLVCQESYCRTHFDRHEEFHSRKPHKVIDATERLQDMICRKHEKELEMYCITDQMCICLMCKEYEHKNHETMSTAAQRTEKQKELKETQMKLQQRVQQRQKDLQQLREAVESQKRCAQTAVEDTDRIFTEIIRLIERRRSELTQMIRDQQKTAVSEAEGLMKRLEKEIDHLRRRGAELEQLSHTQDHIHFLQSFQSLSAPPESTDVSFNPLLSFDDLKESVQQLKVKLEDFCKEEIRKTSDKGTPILNDPFKDTFANIVPKTTRDFLKYYSRFTLDLNTVNKYLCLSSNMITYTNTPQPYPDHPDRFDQLCQVLCRESVSGRCYWEIKWSGYGVCISVSYKGIRRKGQGKDCIFGGNDQSWCLFCYPGDYSFIHNDLKTVLPVQSISSRVGVYVDHSAGILSFYSVSNTMTLIHKVQTTFTQPLYPGFNVNGYKSSVILC", "length": 548 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAS0-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr26", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSTSVVEDQFSCSICKDLLREPVTIPCGHSYCMICITDCWSQDEQRRVYSCPQCRQTFTPRPALNKNVVMAEMVENLKKTGLKSRANYAEAGDVKCDVCAGRKRKAVKSCLLCLNSYCETHFECHEVFHSSKRHKVTDATGRIQEMICSQHDRLLEVYCRTDQKCVCLMCVMDEHKNHDTVSAEAERAEKQIQVGETQTQLQNRIQEKQSKLQQLRESVEIHKSSAQTAVDDCERIFTEIIRCIKRRRLKVTQMIRDREKTEVSRAEGLLKKVEQEIEDLKRRNTELEQLSHTDDHIHFLQSLQPLIIPAESTDSMTVSSLPSYEDVGKSVSELRKKLDDFCKEQIKLISASVSCRTQILPTTKPKTREDFLKYFHQFTLDSQSVHNNLSLSDENRVATFTASMHAYPDHPDRFDTWPQVLCRENVCGRCYWEVEWSGNHGVAIAVSYKSISRKGQGTECKFGYNDQSWRLFCSASGYIFSHNNRKRDLPVVSKIGVYVDQRAGVLSFFRVSDTKMSLIHRVQTTFTQPLYPGFGLNRDSSVKLSSMI", "length": 551 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAU1-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr34", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNQHKVTEATHKLQEMICPQHEKPLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTEQESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFFISSQLSFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISIIPAPEAQTHEQFLQYSQQFTLDPNTAHNRLVLSEGNTAVENNWSVQPYPDHPDRFDGYSQVLCRESVCGRSYWELEWSGNGVEISVSYKSISRKGSGNECLFGRNDQSWSLCCSPLSLSFYHNNINTKLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFYVNYSSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAX9-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr35", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHNYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNRHKVTEATHKLQEMICPQHEKPLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTEQESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEIEMISSRVSSISIITAPEPQTREQFLQYSQQFTLDPNTAHKYLVLSEGNTAVEDKDSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGDGVYLSVSYKSISRKGSGNECGFGHNDQSWSLCCSDYSFSFRHNNIKTKLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLMHTLHTTFTHTLYPGFCVYYSSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQJ4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr95", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCAVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHQGNRHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTAYNRLVLSEGNTAVENKRSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGEDVEISVSYKSISRKGLGNECVFGFNDQSWSLSCSAHSFIFYHNNIKTDLRKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFRVYVCSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B808-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr29", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAHHEFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFCPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHQGNRHKVTEATHKLQEMICPQHEKLLEIFCRTDHCCICYLCLVDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSPLVFDDIAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTAYNRLVLSEGNTAVENKRSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGEDVEISVSYKSISRKGSGNECVFGFNDQSWSLSCSAHSFIFYHNNIKTDLRKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFRVYVCSRLKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YUU8-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSVAHREFSCAVCLDLLKDPVSTACGHNYCMSCITNCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEMVEKLRKSKLQAAGPAQSPAASGDVECDVCSGAKNRAVKSCLVCLNSYCHTHFQLHQQLNPGNQHKVTEATHRLKKLICPQHEKPLEIFCRTDHCCICYLCTMDQHKNHNTVSAVAERTEQQRRLKNIQSSFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLSFNKVTESVSRLRDKLQQFCTEEMKTISSRVSSISIIPAPEPQTREQFLQYSQQFTLDPNTAHTYLVLSEGNTAVENKGSVQPYPDHPDRFDCWHQVLCRESVCGRSYWELEWSGVDVLISVSYKSISRKGSGNECLFGLNDQSWSLCCSADSFSFYHNNIKTDLPKPSVSSSRRGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFCVYYSSRLKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YW98-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEAGISWSQNQFSCSICLDLLKGPVTIPCGHSYCMRCISGYWDQDKQRGVYICPQCRQTFTPRPALGKNTMLAEVVEQLKKTKLQAARPAHCYSESADVECDVCTGDKNKAVKSCLVCLNSYCQNHLEQHESFFRGKRHNLMDATGRLQEMICPQHDKLLEVFCRTDQCCICLLCVDEHKNHEIVSATAERTDKQRQLEETQSKHNQRIQRKQEECVELRVAIESQKCSAQAAVEDTERIFTDLIRSIERRRSEVTQLIRDQEKAQVSAAEGRLERLKQEIDDLRRRDAELEQLSHTDHHIHFLQSFQSLSTPPGSTDSSSITVSSSLSFDDVGKSVSRLREKLEDFCREEIEKISVRGITSIQKPELKTREDFLQYYRPLTLDPNTVNNCLVLSEGNRVFEHTSTNQQYPDHPDRFDCFLQVLCRENVYGRCYWEVEWSGDVEILVAYKSISRKGLGDECGFGRNDQSWGLSCSRSRCSFCHNKKQTKLPVMSNSSRIGVYVDHSAGTLSFYSISNTMSLIHRVHTTFTQPLYPGFGIDSLYSLFSETKQKIKLSDLKI", "length": 561 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1N9-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25 isoform X1", "gene_name": "ftr73", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCLHVADCFEASAKMSESSSSEYVDQFSCPVCLDLLKEPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCRESFSQRPLLKKNTLIAEMMETLQKTALQTPAAAAVDCDVCTTEKNRAVKSCLQCLASFCQTHLQLHYESPAFMKHKLVDASRHIQENICPSHGRPLEIYCQDDHQCICCMCTDNHKGHSVVSVDSEWTSKKEELEEMKLKCLKLIKDREKGQQDLSKATKNLKSSADEAVERMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFKDVPSFTSHTHLSFKDLSISAFREALEDACQQQTDAISREVSNVHVVQTPQPKSEHDFLQYYCKLQMDSSTAHRELKLSEEKRKVSFSDEVQPYPDHPQRFDWFHYILCREGLTGRCYWEVECSGDIWGVAVCYRGIRRKGNSDDCKLGFNKVSWRLNRLQQNITYIRNKVQVRIKAGCFSRIGVYLDHRAGILSFYSVSDTNTLLYKVQTTFTEPLYPAFIIGQGSSVRIFDKRTAQMEELT", "length": 567 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PJ13-1", "protein_name": "Tripartite motif-containing protein 16 isoform X1", "gene_name": "ftr11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVCLAQEQFSCSICLDLLKDPVAIPCGHSYCMSCISDCWDQDERKGVYSCPQCRQTFTPRPALGKNTMLTEVMENIRKRKLQAGDVECDVCTGRKFKAVKSCLVCLESYCQTHFQHHEEFHSRKRHKVTDATGRLQEMICPQHEKLLEIFCRTDQCCICYLCTMDKHKNHDTVSAAAEWTDKKIQLAEMQKTTHQRMVERQKEREELRAAVESHKRSAQAAVEDTESIFTELIFSFERSCSEVTQLITDQQKAAEGRAEERLKQLEQEINDLRRRNTELEQLSHTDHHIHFLKSFQSLSSPPGSTDSSSITVSSRISFDDVGKLSHLRKKLEQFCREEIEKISSKVRDINIISISAEPKTRQEFLQYSRQLTFDPNTVNTSLVLSKKNRVIEYTDKVQQYPDHPDRFDCWPQVLCRESECGRFYWEVEWNGYIEISVSYKSISRKGRGNECVFGCNDQSWSLFCSRSRFSFRHNKQQTKLPVLSISSRIGVYVDHSAGTLSFYNVSDTMSLIYRVHTTFTQPLYPGFWVFAGSILFTTDTL", "length": 545 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PRK9-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr41", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEVRISVDQIEFMCPVCLDLLKDPVTLHCGHSYCKSCITDFWDQEYEKRIYSCPQCRQSFTPRPALAKNTMLAEVVEKLKKTKPPADCCAGAGDVQCDACTGRKYKAVKSCLQCQESYCQTHFERHEEFHSRKPHKVIDATGQLRDMICQKHGKELEIYCITDQQCICELCKEYEHKNHATVSTAEQMTEKQQELKERQVKLQQREKALRKLKNAVESQKRSAQTAVEDTEKIFTELIHSIQKKGTELTQVISSAEKTAVSQAEEHMEYLEQEIEDLRRRNAELERLSQTQEHVNFLQRFQSLPAPLESTDGYFSSFLCFDAMKESVHELKSKLENLCKEEIKMILDRVTSFVPKTRNDFLQYSIKLTLDLHTAHKCLSKKRKVVTCTKKEQPYPDHPDRFHDWPQVLCTERVRGRRYWEVEWSGDKGVCISASYKSISRTGTGNECAFGGNDHSWSLFCSPLRYLFWHNNIQSDLTVKPNSHKIGVYVNVGAGTLSFYNVSDEMSLIHTFQTTFTQPLFPGFTVGFGSSVKLKHR", "length": 537 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6I4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr94", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEARFSQDEFLCPVCLELLKDPVSLHCGHNYCKGCISGFWDQEDEKRVYSCPQCRQTFSQRPALAKNTMLAEVVEKLKKTKPPADCKAGAGDVQCDVCTGTKYKAIKSCLQCQESYCQTHFENHEEFHFRKSHKVIDATGQLQDMICQKHKKELEIYCITDQQCICELCKEFEHTTHETLSVAEQRKEKQKELKETQVKLQESLQQRQQELQQLREAVESHKRSAQTAVKDTERIFTELICSIEKRCSELTQIIRDQEKTAVSRAEGHMEWLEQEVENLRRRNAELEQLSHKKDHVQFLKSFQSFSAPPESTDVLSSSLLCFDGLSESVSQLKDKLEDFCKKELKKISDRVTKTSPKTRNDFLQYSHQFTLDLNTMNDHLRLSESNRVITGAETAQPTFDHPDKFNGWPQVLCRESVRGRCYWEIEWSGDVGVILSVSYKSISRKGFGNECAFGGNDKSWSLACFPTRYSFWHNSKRTDLSVKPISRMIGVYVDESAGILSFYGISNTISLIHTVKTTFTQPLYPGFTVDPRSSVKLC", "length": 539 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TBM3-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr37", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSVAHHEFSCAVCLDLLKDPVSTACGHNYCMSCITNCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNQHKVTEATHKLKKLICPQHEKPLEIFCRTDQLCICYLCTMDQHKNHNTVSAVAERTEQQRRLKNIQSSFQQRLQERQKELEKLKKAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSPLVFDDIAESVSHLREDLEHFGKKEIKLISRRVSSISRIPAPVPKTREQFLQYSQQFTLDPNTVNNWLVLSERNTVVKYKGSVQRYPDHPDRFNCWYQVLCRESVCGRSYWELEWSGVDVYLSVSYKSISRKGSGNECLFGYNDHSWSLWCSADSFIFYHNNKQTKLPKPSVSSTRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHALYPGFCVHYSSRVKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UV20-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X1", "gene_name": "ftr91", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESMLSQQKDQFSCSVCLDPLKQPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCREIFRQKPLLKKNTLIAEMMETLQKTALQTPAAAVDCDVCTTEKNRAVKSCLQCWASFCQTHLQLHYKSPAFMNHKLVEASRHICPNHKKPQDIYCQDDHQCICYLCMIDSHKGHRVVSVEAELINKKNKLKEMKLKCQTLIKERQRGWQELSIAMKLFKSSADEAVEKMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFEDVPSFTSHTHLSFKDLSFSAFREALEDACQQQTDAISREVSNIHVVKPPDLKTQNDFLQYFCQIHLDRNTAHKNLKVTEDNKKVSCSDKDQKYPDHPERFDGYCHVLCREGLTGRCYWEVECSGKYWAVAVCYRGISRKGVSDDCKLGFNKISWRLGYYLQNFSFIHGKAHVRLPPASRIGVYLDHKAGMLSFYSVSDTMTLLHRVQTTFTEPLYPAFYSGSGSSVKIIE", "length": 537 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UV86-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr38", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAHCKFSCSECLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQELNPGNQHKVIEATHRLKEMICQQHKKLLEIFCRTDHCCICSLCVLDGHKNHDTVSAAAQRTKKQCRLKKTQSRFQQRLQERQKELEELREAVESHKHSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSFQSLSVPPGSTDSSSFFISSQLSFNKVTESVSRLSDKLQQFCTEEMKTISDKVRFISIIPAPEPQTREQFLQYSQQFTLDPNTVNKKLVLSEGNTAVEINGSDQPYPDHPDRFDGFSQVLCKESVCGRSYWELECSSASVYLSVSYKSISRKGSGNECRFGNNDQSWSLFCSDNSFSFWHNNIKTDLRKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFYVYLAKVKICDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UVE5-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAECSISVAQDQFSCSICLDLLKDPVAIPCGHSYCMSCISDCWDQDEQRGVYSCPQCRQTFTPRPALGKNTMLAEVVGKLKKTKLQAARPAQCYSESADVECDVCTGDKNKAVKSCLMCLNSYCQNHLEQHASFFRSKKHNLMDATGRLQEMICPQHDKLLEVFCRTDQCCICYLCTMDGHKNHNTVSAAAERTDKHRQLEETQSKLHQRIQRKQVEFEELRAAVESHKCSAQAAVEDTERIFTDLIRSIERSRSEVTQLIRDQEKAAVSEAEGRLERLEQEIDDLRRRDAELEQLSHTDHHIHFLQSFQSLSTPPGSTDSSSITVSSSLSFDDVGKSVSRLREKLEHFCREEIEKITWRMRDYKGTTPTPEPKTHQEFLQYTCWLFLDLNTMNKNLVLSKGNRVIELSSTVQQYPDHPDRFDCWHQVLCRESVCGRCYWEVEWSGSVGISVAYKSIGWKGQGTEFGYSNQSWCLFCSGSICTFVHKSKHTVLPLVSSSSRIGVYVDHSAGTLSFYSVSDTMSLIHRVHTTFTQPLYPGFELVSYNPCGSKLKLCEL", "length": 557 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58GXY0-1", "protein_name": "FinTRIM family, member 23 isoform X1", "gene_name": "ftr23", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGFSETGKCSPTLLSEMAESSISVAEDQFSCSVCLDLLKEPVTIPCGHSYCMNCITDCWNQDEQRRVYSCPQCRQTFTPRPALNKNVVMVEMVEKLKTGSRNAASYAGPGDVECDVCTGRKRKAVKSCLMCLSSYCQTHLEQHDSFFKDKRHHLINATGRLRQMICSKHDRLLEVYCHTDQKCICLLCMMDEHTGHQTVSIKTERAEKQKQLLDLQKNFQKTIQEREEEVWDLKHAVKTHKHSAQTAVEESERIFTRLFHFIERRQSEVSQMIRDRKKTEVSRAEGLLKKLEEEIEDLKRRNTELEQLSHTDDHIHFLQSFHSLSAPPESPESSDVTSLLFYDDVGETLSVLKEKLEDACKEATENMSVLETPYMEIVSTSELINRDKFLQYFHHLTLDSNTAHKYLRLSEGNRVATFIGADQSYPAHPDRFHDFSQVLCRESVCGRCYWEVEWSGEAGVGISVSYKSIRRKGEGFDCVFGFNDQSWRLSCSNSRYTLRHKQLSTKLRVPSGSNRIGVYVDHKAGILSFFNISDTMSLIHRVQTTFTQPLYPGFGINFGSTVKLKSAENL", "length": 570 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58I1B9-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X2", "gene_name": "ftr30", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTHTGSVRAERNRKFTQIPCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKQQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQQLNPGNQHKVIEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEAQTREQFLQYSQQFTLDPNTVNNCLVLSEGNTAVDYKDSVQPYPDHPDRFDCSYQVFCRESVCGRSYWELEWSGVVYLSVSYKSISRKGRNIECGFGNNDQSWSLECSPYSFSFWHNKIKTALPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFGVYSSRLKLCDLTV", "length": 562 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ACD6B7A1-1", "protein_name": "LOW QUALITY PROTEIN: tripartite motif-containing protein 16", "gene_name": "ftr42", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAETRFSQDEFLCPVCLDLLKDPVAIHCGHSYCKSCITDFWNMEDEKGIYSCPQCRQTFSPRPALAKNTMLAEVVDKLKKTTPPADCYAGAEDVQCDACTGTKYKAIKSCLQCLESYCQTHFERHEEFHSRKPHKVIDATGRLQDMICPKHEKELEVYCITDQQCICELCKEYEHKNHKTVSAAAQRTEKQKELKETLVKLQERLQQRQKDLQQLRAAVESHKQSAQTAVEDTDRIFTELIYSIEKRRSELTQMIRDQEKTTRSRAERHMEQLEQEIEDLRRRNTELEQLSHTHHHIHFLQSFQSLSAPPESTDVSFSSLLCFDGLRESVSQLKVKLEDFCIEEIEKFTERVTKTVPKTRNDFLQYSHKLTLDLNTAHKLLHLSERNRIIICTETEQPYPDHPDRFDSWRQVLCRESVRGRCYWEIEWSGIKGVCISVSYKSISRKGFGNECVFGGNDQSWGLFCSTSRYSLWHNKKRSDLPLKPISRRIGVYVDVGAGTLSFYSIFDTMSLIHTVQTTFTQPIYPGFTVDPRSSVKLC", "length": 539 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LMT9-1", "protein_name": "Tripartite motif protein 80", "gene_name": "Trim80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSAKLGSFLRKGHLDRETMKQQPQRTVRRRRSPVHRAAKYLAVIDMQKISRPTQDKSPSELSTQSSRTSLQLLMSSNSSQHLLEDQVLCPICLDVFRNPVTTACGHNFCMTCLQSFWDHQADTGETYYCPQCREAFPSRPRLCKNVILGEMVACFTLAKSQTSGPLWGLAGPTDVPCDFCSPQKLKATKSCLQCMASLCEKHLHSHFEDPLFQEHQLLDPVWDLKNRLCRKHRKLRQMYCRTEGSCVCGACLLEEHQNHDTTPLEDERARKEVEVRKIQANVENQMLIIASDSQKHQGRVSFLSKLIQTMREEVNTCFSEILHEVKQLQMKVLDFVENEETVALGMLGNSMQQSHSRLLKLEGDSVWLHGLLANKSDEQFLQEFPTLKHFPACVEPLLGTNCEETQSFLQLPETLAQLRIRLMDIGLNFINQLLLKGIRMNSYEVLPATVDRKTLLQNYCNLNFDSSMASEELFLFKETHSVLNLGILLEPSTTSPLPGFKQWPQVLCCPGLSEGCHYWETEVSDSWMCLGVTYRRNPSMSGRHRRNIVYLLGRNPYSWCLEWDSLKFSVWHNNTQTVLHGSYHHTLGVALDFRAGCLSFYGVAGDVSLLYRFLTSFLEPLYPAVMVSSGASLTLKQYPEA", "length": 642 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-319", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-319#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAX6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAX6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PAX6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAX6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PAX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAX6" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 189, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PAX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAX6" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 370, "end_pos": 565, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PAX6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAX6" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 58, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PB91-1", "uniprot_ac": "A0A8M9PB91", "uniprot_id": "A0A8M9PB91_DANRE", "mass": { "chemical_mass": 38518.0, "monoisotopic_mass": 38518.0 }, "refseq": { "ac": "XP_021323883", "name": "fMet-Leu-Phe receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323883" }, "gene_names": [ { "name": "si:ch73-160i9.1", "type": "recommended", "evidence": [ { "id": "A0A8M9PB91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91" } ] }, { "name": "si:ch73-160i9.1", "type": "synonym", "evidence": [ { "id": "XP_021323883", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323883" } ] } ], "protein_names": [ { "name": "fMet-Leu-Phe receptor", "type": "synonym", "evidence": [ { "id": "XP_021323883", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323883" }, { "id": "A0A8M9PB91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323883.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323883", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323883" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PB91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch73-160i9.1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141212-254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-254", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PB91", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PB91", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14974", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14974", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "793256", "url": "https://www.ncbi.nlm.nih.gov/gene/793256", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:793256", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793256", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PB91", "url": "https://www.orthodb.org/?gene=A0A8M9PB91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24225", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24225", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24225:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24225:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323883", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323883", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PB91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PB91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-141212-254", "url": "https://zfin.org/ZDB-GENE-141212-254", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTNNTTFSFLSNSKISIHYEKTTVDMVFYTIVILLGTTGNSVVIWVAGFHMKSNVTKVWLVNLAVADLIFCLTRISSLISKVFFDYWPFGVFLCKFNGFIKYANMFCSVFLLAVISVDRALCIWHPFFTRERRTVCAARVVSVGVWIVAVIFSSPYFVYRQVFPGKNNLSHCSLKVNGSSETGISTKYVYYFIRFICGFLLPFLIIFICYTLAAIGIRRSRLSRKAKPLRILAVLVCAFFLCWAPYHFLGLVKLVNKDNEVVKIGWNMASNLAYFNSCINPILYFFMGLDVSRRCNQSLSGIFRRALMEEGQSLSQQGIGEDISNSFLKTIGVECETKV", "length": 339, "header": "tr|A0A8M9PB91-1|A0A8M9PB91_DANRE Isoform 1 of fMet-Leu-Phe receptor OS=Danio rerio OX=7955 GN=si:ch73-160i9.1 PE=3 SV=3 CANONICAL=A0A8M9PB91-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PB91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91/entry#A0A8M9PB91-1", "sequence": { "sequence": "MTNNTTFSFLSNSKISIHYEKTTVDMVFYTIVILLGTTGNSVVIWVAGFHMKSNVTKVWLVNLAVADLIFCLTRISSLISKVFFDYWPFGVFLCKFNGFIKYANMFCSVFLLAVISVDRALCIWHPFFTRERRTVCAARVVSVGVWIVAVIFSSPYFVYRQVFPGKNNLSHCSLKVNGSSETGISTKYVYYFIRFICGFLLPFLIIFICYTLAAIGIRRSRLSRKAKPLRILAVLVCAFFLCWAPYHFLGLVKLVNKDNEVVKIGWNMASNLAYFNSCINPILYFFMGLDVSRRCNQSLSGIFRRALMEEGQSLSQQGIGEDISNSFLKTIGVECETKV", "length": 339, "header": "tr|A0A8M9PB91-1|A0A8M9PB91_DANRE Isoform 1 of fMet-Leu-Phe receptor OS=Danio rerio OX=7955 GN=si:ch73-160i9.1 PE=3 SV=3 CANONICAL=A0A8M9PB91-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:793256", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793256", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AM80-1", "protein_name": "Formyl peptide receptor 2", "gene_name": "Fpr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEANYSVPLNVSEVVVYDSTISRVLWILSMVVLSITFVLGVLGNGLVIWVAGFRMVHTVTTTCYLNLALADFSFTATLPFFVISTAMKEKWPFGWFLCKLVHIVVDINLFGSVFLIALIALDRCICVLHPVWAQNHRTVSLARKVVVGPWILALILTLPIFVFMTTVRVPGGNVYCTFNYASWGKTVEEVLDVANTCETVRGTIRFVIGFTMPMSIVAICYGLIAVKIHRRALVNSSRPLRVLTAVVVSFFICWFPFQLVALLGTIWFKELLFNTRYGILKMWVNPTSSLAYFNSCLNPMLYVFMGQDFRERLIHSLPSSLERALSEDCGQTSDTGTNSALPPADIEIKAI", "length": 351 }, "evidence": [ { "id": "MGI:1278319", "url": "https://alliancegenome.org/gene/MGI:1278319#orthology", "database": "AGR" }, { "id": "MGI:1194495", "url": "https://alliancegenome.org/gene/MGI:1194495#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M6YSE5-1", "protein_name": "Formyl peptide receptor 2-like", "gene_name": "si:dkey-42l23.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENSSFGLKNLTGNSTDKNAVEDKGFKIFLACIFFSTVSVGLIGNGLVIFLAGCRMKMTFNSIWFLNLAIADFIFILFSITNASLTLSKQHSVVKEYFLFIATSINLFASIWSLVVISLDRCLCTWMAVWAQNNRTLRKARIICIIIWVSSIGYILPYFTVFNITGTILVTYGFIVVFLIPFLIIASSYIAIGVKINRLKKRKQLRSYRLIITVILTFFICSFPHNVCWIWMVWAKNNNWTLTDQFWKLFVFTFYLMNLNSSLNPFLYVFMCDDFKKKLKQSLVLVLETAFAEDHLDIKEMRHTKMINRQNKPHLNC", "length": 317 }, "evidence": [ { "id": "MGI:1278318", "url": "https://alliancegenome.org/gene/MGI:1278318#orthology", "database": "AGR" }, { "id": "MGI:1278319", "url": "https://alliancegenome.org/gene/MGI:1278319#orthology", "database": "AGR" }, { "id": "MGI:107443", "url": "https://alliancegenome.org/gene/MGI:107443#orthology", "database": "AGR" }, { "id": "MGI:1278317", "url": "https://alliancegenome.org/gene/MGI:1278317#orthology", "database": "AGR" }, { "id": "MGI:1194495", "url": "https://alliancegenome.org/gene/MGI:1194495#orthology", "database": "AGR" }, { "id": "MGI:2448177", "url": "https://alliancegenome.org/gene/MGI:2448177#orthology", "database": "AGR" }, { "id": "MGI:2448176", "url": "https://alliancegenome.org/gene/MGI:2448176#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LY43-1", "protein_name": "Formyl peptide receptor 2 like 2", "gene_name": "Fpr2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEANISMPRNGSEVGFYDSTTSTVLWILSLVVLCITFVLGVLGNGLVIWVSEFRMAHTVTTVCYLNLALSDFSFMATLPLQIISMVMRGKWLFGWFLCKLVHIIANINLFVSIFLITLIAMDRCTCVLHPVWSQNHRTVSLARKVVVGAWIFALLLTLPHFLFLTTVKDARGEVHCISKFESWVATPEEQLKVSITATTASGIINFIIGFSMPMSFIAICYGLMAVKICRRGFVKSSRPLRVLTAVAVSFFVCWFPFQLIMLLGNILNKETLSIIHILVNPANTLASFNSCLNPILYVFLGQEFRDRLMHSLSASLERALRED", "length": 323 }, "evidence": [ { "id": "MGI:1278318", "url": "https://alliancegenome.org/gene/MGI:1278318#orthology", "database": "AGR" }, { "id": "MGI:2448177", "url": "https://alliancegenome.org/gene/MGI:2448177#orthology", "database": "AGR" }, { "id": "MGI:2448176", "url": "https://alliancegenome.org/gene/MGI:2448176#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A4FUQ5-1", "protein_name": "Formyl peptide receptor-related sequence 4", "gene_name": "Fpr-rs4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVNISMPLNGSEVVFYDSTTSRVLWILSLVVLFITFVLGVLGNGLVIWVAGFQMAHTVTTVSYLNLALSDLSFMATLPLHIISMVMRGKWLFGWFLCKLVHIIANINLFVSIFLITLIAMDRCICVLCPVWSQNHRTVSLARKVVLGAWIFALLLTLPHFLFLTTVRDARGDVYCISKFESWVATSEEQLKVSVIAATASGIINFIIGFSMPMSFIAICYGLMAAKICRRGFVNSSRPLRVLTAVAVSFFVCWFPFQLIMLLGNIFNNETLSIIHMLVNPANTLASFNSCLNPILYVFLGQEFRDRLIYSLYASLERALRED", "length": 323 }, "evidence": [ { "id": "MGI:1278317", "url": "https://alliancegenome.org/gene/MGI:1278317#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-254#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A7Q2-1", "protein_name": "N-formylpeptide chemoattractant receptor", "gene_name": "Fpr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTNMSAVNFMNMSGSTRSVSAGYIVLDIFSYLIFALTFVLGVLGNGLVIWVAGFRMKRTVTTISYLNLAIADFCFTSTLPFYIVSLVMGGIWPFGWFMCKFIYTVIDINLFGSVFLIALIALDRCVCVLHPVWAQNHRTVTLAKKVIIVPWICAFLLTLPVIIRVTTVPNRLGPGKTACALDFSPWTKDRAEKDKVAITMYTVRGIIRFILGFSTPMSIVAICYGLIATKIHRQGLIKSSRPLRVLSFVVAAFFLCWCPFQVVGLIRTIQIREHLRNIPQSTLTAMKITSSLAFFNSCLNPILYVFMGQDFRQRLIHSLPASLERALSEDSAQTSDTGTNLGANSIPENPANAM", "length": 355 }, "evidence": [ { "id": "RGD:1310883", "url": "https://alliancegenome.org/gene/RGD:1310883#orthology", "database": "AGR" }, { "id": "MGI:107443", "url": "https://alliancegenome.org/gene/MGI:107443#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-254#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FF45-1", "protein_name": "Chemerin-like receptor 1", "gene_name": "fpr1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMDPFNFTESPPNHNSSEYDDDYVDYQNSELGKSLNIMSLIVYSLAFVLGVVGNGIVIWVTGFKMKRTVNTVWFLNLAVADFLFTAFLPLSVAYTAMGFHWPFGQFMCKFNSTLGFLNMFASVYILVVISVDRCVSVVRPIWAQNHRNVGRASAVSFGVWLFALLLSSPYFVFKDTAQDNRDPKIINCFNNFAFSDADTQEVEDLRMLRHRAMIITRFIIGFVVPFVIIVSCYAVIIHRLQRNRSMSGKTGRPFRIIAAVITAFFLCWAPYHILVLIEMVNHMSTEYSPTLQHVITVGIPIVTSLAFLNSCLNPLLYVFMGQDFKDKVRKSILKVLETAFTEEVSRTNTWTNSMTTIRNKENGSKSFSDAEV", "length": 372 }, "evidence": [ { "id": "MGI:107443", "url": "https://alliancegenome.org/gene/MGI:107443#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O08790-1", "protein_name": "Formyl peptide receptor-related sequence 1", "gene_name": "Fpr-s1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METNYSIPLNGSDVVIYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVTTIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIAVDVNLFGSVFLIAVIALDRCICVLHPVWAQNHRTVSLARNVVVGSWIFALILTLPLFLFLTTVRDARGDVHCRLSFVSWGNSVEERLNTAITFVTTRGIIRFIVSFSLPMSFVAICYGLITTKIHKKAFVNSSRPFRVLTGVVASFFICWFPFQLVALLGTVWLKEMQFSGSYKIIGRLVNPTSSLAFFNSCLNPILYVFMGQDFQERLIHSLSSRLQRALSEDSGHISDTRTNLASLPEDIEIKAI", "length": 351 }, "evidence": [ { "id": "MGI:1194495", "url": "https://alliancegenome.org/gene/MGI:1194495#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-254#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O88536-1", "protein_name": "Formyl peptide receptor 2", "gene_name": "Fpr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESNYSIHLNGSEVVVYDSTISRVLWILSMVVVSITFFLGVLGNGLVIWVAGFRMPHTVTTIWYLNLALADFSFTATLPFLLVEMAMKEKWPFGWFLCKLVHIVVDVNLFGSVFLIALIALDRCICVLHPVWAQNHRTVSLARKVVVGPWIFALILTLPIFIFLTTVRIPGGDVYCTFNFGSWAQTDEEKLNTAITFVTTRGIIRFLIGFSMPMSIVAVCYGLIAVKINRRNLVNSSRPLRVLTAVVASFFICWFPFQLVALLGTVWFKETLLSGSYKILDMFVNPTSSLAYFNSCLNPMLYVFMGQDFRERFIHSLPYSLERALSEDSGQTSDSSTSSTSPPADIELKAP", "length": 351 }, "evidence": [ { "id": "MGI:1278319", "url": "https://alliancegenome.org/gene/MGI:1278319#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-254#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O88537-1", "protein_name": "Formyl peptide receptor-related sequence 3", "gene_name": "Fpr-rs3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEANSSIPLNGSEVVFYDSTTSRVLWILSVIVLSITFVLGVLGNGLVIWVAGFRMAHTVTTICYLNLALGDFSFMVTLPLHIISMVMKGKWLFGWFLCKFVLSIVHINLFVSVFLITLIAMDRCTCVLHPVWVQNHRTVSLARKVIVGAWILSLLLTLPHFLFLTTVRDARGEVHCTCNFESVVANPEEQLKVSITVSTATGIISFIIGFSLPMSFIAVCYGLMAAKICRKGFLNSSRPLRVLTAVAISFFMCWFPFQLIILLGNIWNKETPSSIHILLNPASTLASFNSCLNPILYVFLGQEFREKLIYSLSASLERALREDSVLSSGKSSNFSSCPADSEL", "length": 343 }, "evidence": [ { "id": "MGI:1278318", "url": "https://alliancegenome.org/gene/MGI:1278318#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-254#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P21462-1", "protein_name": "N-formyl peptide receptor 1", "gene_name": "FPR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK", "length": 350 }, "evidence": [ { "id": "RGD:1310883", "url": "https://alliancegenome.org/gene/RGD:1310883#orthology", "database": "AGR" }, { "id": "MGI:107443", "url": "https://alliancegenome.org/gene/MGI:107443#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P25089-1", "protein_name": "N-formyl peptide receptor 3", "gene_name": "FPR3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METNFSIPLNETEEVLPEPAGHTVLWIFSLLVHGVTFVFGVLGNGLVIWVAGFRMTRTVNTICYLNLALADFSFSAILPFRMVSVAMREKWPFGSFLCKLVHVMIDINLFVSVYLITIIALDRCICVLHPAWAQNHRTMSLAKRVMTGLWIFTIVLTLPNFIFWTTISTTNGDTYCIFNFAFWGDTAVERLNVFITMAKVFLILHFIIGFSVPMSIITVCYGIIAAKIHRNHMIKSSRPLRVFAAVVASFFICWFPYELIGILMAVWLKEMLLNGKYKIILVLINPTSSLAFFNSCLNPILYVFMGRNFQERLIRSLPTSLERALTEVPDSAQTSNTDTTSASPPEETELQAM", "length": 353 }, "evidence": [ { "id": "MGI:1194495", "url": "https://alliancegenome.org/gene/MGI:1194495#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P25090-1", "protein_name": "N-formyl peptide receptor 2", "gene_name": "FPR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METNFSTPLNEYEEVSYESAGYTVLRILPLVVLGVTFVLGVLGNGLVIWVAGFRMTRTVTTICYLNLALADFSFTATLPFLIVSMAMGEKWPFGWFLCKLIHIVVDINLFGSVFLIGFIALDRCICVLHPVWAQNHRTVSLAMKVIVGPWILALVLTLPVFLFLTTVTIPNGDTYCTFNFASWGGTPEERLKVAITMLTARGIIRFVIGFSLPMSIVAICYGLIAAKIHKKGMIKSSRPLRVLTAVVASFFICWFPFQLVALLGTVWLKEMLFYGKYKIIDILVNPTSSLAFFNSCLNPMLYVFVGQDFRERLIHSLPTSLERALSEDSAPTNDTAANSASPPAETELQAM", "length": 351 }, "evidence": [ { "id": "MGI:1278319", "url": "https://alliancegenome.org/gene/MGI:1278319#orthology", "database": "AGR" }, { "id": "MGI:1194495", "url": "https://alliancegenome.org/gene/MGI:1194495#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P33766-1", "protein_name": "N-formyl peptide receptor 1", "gene_name": "Fpr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTNMSLLMNKSAVNLMNVSGSTQSVSAGYIVLDVFSYLIFAVTFVLGVLGNGLVIWVAGFRMKHTVTTISYLNLAIADFCFTSTLPFYIASMVMGGHWPFGWFMCKFIYTVIDINLFGSVFLIALIALDRCICVLHPVWAQNHRTVSLAKKVIIVPWICAFLLTLPVIIRLTTVPNSRLGPGKTACTFDFSPWTKDPVEKRKVAVTMLTVRGIIRFIIGFSTPMSIVAICYGLITTKIHRQGLIKSSRPLRVLSFVVAAFFLCWCPFQVVALISTIQVRERLKNMTPGIVTALKITSPLAFFNSCLNPMLYVFMGQDFRERLIHSLPASLERALTEDSAQTSDTGTNLGTNSTSLSENTLNAM", "length": 364 }, "evidence": [ { "id": "RGD:1310883", "url": "https://alliancegenome.org/gene/RGD:1310883#orthology", "database": "AGR" }, { "id": "MGI:107443", "url": "https://alliancegenome.org/gene/MGI:107443#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-254#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3SXG2-1", "protein_name": "Formyl peptide receptor-related sequence 6", "gene_name": "Fpr-rs6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEANFSIPQNGSEVVFYDSTTSRVICIFLVVVLSITFLLGVIGNGLVIYVAGFRMTHTVTTICYLNLALSDFSYMASLPFQITSIVMNGEWLFGWFLCKFVHMIINVNLFLSIFLITFIAMDRCICVLHPVWAQNHRTVNVATKVIFGAWILVLMLIFPHCIFVTTVKDESGKVHCICNFESWAATPEEQVKVSMTVSLISVTISFIIGFSIPMIFIVICYGLMAAKIGRRGFVNSSRPLRVLTAVAISFFVCWFPFQLIFLLGNIGNKETQNNIDTWVNTASTLASFNSCLNPILYVFLGQQFRERLIYSLSASLERALREDSALNSDKTRNLSSQRL", "length": 339 }, "evidence": [ { "id": "MGI:2448176", "url": "https://alliancegenome.org/gene/MGI:2448176#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-254#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q71MR7-1", "protein_name": "Formyl peptide receptor-related sequence 7", "gene_name": "Fpr-rs7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEANFSIPQNGSEVVFYDSTTSRVICIFLVVVLSITFLLGVIGNGLVIYVAGFRMTHTVTTICYLNLALSDFSYMTSLPFQITSIVMNGEWLFGWFLCKFVHMIINVNLFLSIFLITFIAMDRCICVLHPVWAQNHRTVNLARKVILGSWILVLMLIFPHFFFLTTVKDESGKVHCICNFESWAATPEEQVNMSMTVSLISVTLSFIVGFSIPMIFIVICYGLMAAKIGRRGLVNSSRPLRVLTAVAFSFFVCWFPFQLIFLLGNIGNKETQNNIDAWVNPASTLASFNSCLNPILYVFLGQQFRERLIYSLSASLERALREDSALNSDKIRNLSSQT", "length": 338 }, "evidence": [ { "id": "MGI:2448177", "url": "https://alliancegenome.org/gene/MGI:2448177#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-254#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "complement receptor activity", "id": "GO:0004875", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004875", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PB91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91" } ], "pmid": "" }, { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PB91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "complement receptor mediated signaling pathway", "id": "GO:0002430", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002430", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PB91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91" } ], "pmid": "" }, { "name": "chemotaxis", "id": "GO:0006935", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006935", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PB91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91" } ], "pmid": "" }, { "name": "inflammatory response", "id": "GO:0006954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006954", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PB91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91" } ], "pmid": "" }, { "name": "positive regulation of cytosolic calcium ion concentration", "id": "GO:0007204", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007204", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PB91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91" } ], "pmid": "" }, { "name": "phospholipase C-activating G protein-coupled receptor signaling pathway", "id": "GO:0007200", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007200", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PB91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PB91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PB91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB91" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 284, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073787727", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073787727" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBF9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101885373", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBF9", "locus": {} } ], "crossref": [ { "id": "A0A8M9PBF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PBF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00038", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00038", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": 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"length": 1076, "header": "tr|A0A8M9PBF9-1|A0A8M9PBF9_DANRE Isoform 1 of Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2-like OS=Danio rerio OX=7955 GN=LOC101885373 PE=3 SV=2 CANONICAL=A0A8M9PBF9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885373", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885373", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBF9" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBF9" } ], "pmid": "" }, { "name": "HCN channel complex", "id": "GO:0098855", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098855", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "sodium ion transmembrane transport", "id": "GO:0035725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035725", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBF9" } ], "pmid": "" }, { "name": "regulation of membrane depolarization", "id": "GO:0003254", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003254", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBF9" } ], "pmid": "" }, { "name": "potassium ion transmembrane transport", "id": "GO:0071805", "url": 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nucleotide-binding", "eco_id": "ECO_0000259", "start_pos": 638, "end_pos": 744, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 501, "end_pos": 503 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PBW3-1", "uniprot_ac": "A0A8M9PBW3", "uniprot_id": "A0A8M9PBW3_DANRE", "mass": { "chemical_mass": 54688.0, "monoisotopic_mass": 54688.0 }, "refseq": { "ac": "XP_021328551", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328551" }, "gene_names": [ { "name": "LOC101883788", "type": "recommended", "evidence": [ { "id": "A0A8M9PBW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBW3" } ] }, { "name": "LOC101883788", "type": "synonym", "evidence": [ { "id": "XP_021328551", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328551" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PBW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBW3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021328551", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328551" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328551", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328551" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBW3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBW3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101883788", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBW3", "locus": {} } ], "crossref": [ { "id": "A0A8M9PBW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PBW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "101883788", "url": "https://www.ncbi.nlm.nih.gov/gene/101883788", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013761", "url": 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phase-specific E3 ubiquitin-protein ligase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328572" }, "gene_names": [ { "name": "LOC100536045", "type": "recommended", "evidence": [ { "id": "A0A8M9PBY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBY0" } ] }, { "name": "LOC100536045", "type": "synonym", "evidence": [ { "id": "XP_021328572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328572" } ] } ], "protein_names": [ { "name": "G2/M phase-specific E3 ubiquitin-protein ligase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021328572", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328572" }, { "id": "A0A8M9PBY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBY0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021328572.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328572", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328572" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBY0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBY0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100536045", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBY0", "locus": {} } ], "crossref": [ { "id": "A0A8M9PBY0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PBY0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100536045", "url": "https://www.ncbi.nlm.nih.gov/gene/100536045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000569", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000569", 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"MYCPYCGASLDSCPSFCSKCGKNITFLKGKVPDGNEPSTSGGKTETSSVDCFMKFRAIKEKERKTFFTKKSHASKKDKGVKIYIGSMERHCGVLKPLRGKRLPLEVETNWTSEQVLIAGKKKVKDFNQDMEDGPYVLLYPDGSEVKNIPGTNTPFKLQLYKEAIGKAYQRITLYICTVEDFFATDCNEDSSSEDSVVQVKFTSHSQHDESDTLIWDSADEAGSSSHRPPDHSLPVQEQEAGKIRTNIQEHVRDQQKCYTNYTRLYAPIVIESDSEGSDQSTQHVEEEWISDAISAADIVSDLSQKIIRTSCSRFNINRANIWDGAVRGFKRASYDPLHDMLVKFTDDEGSTEDAVDTGGPKREFLTLLMDCLKARRIFDGPENGRFLTFNNAAVREDEYFLAGRMIAVSIVHGGPGPRFLSNMLYDYLIGRTDINGTVEDVTDETMKAALIEISSAESLDELHTLIEKYESLLQTAGCFDFPQSVKGKDNIVKDFILWYIIYRNQYSVQRFRDGLSTLDVINALQQHPIAFRPYMCYSVDRLTAVSLEDVFKPQLSEPGSTRRQEETRILGYWRDYLLDTGEQETGVSLQNILMFATGLDSLPPSTIVPQPRLIFERSSKFPIASTCANTIKLPVSKSYDEFKNAMDFGIQNSPGFGLR", "length": 659, "header": "tr|A0A8M9PBY0-1|A0A8M9PBY0_DANRE Isoform 1 of G2/M phase-specific E3 ubiquitin-protein ligase isoform X1 OS=Danio rerio OX=7955 GN=LOC100536045 PE=4 SV=2 CANONICAL=A0A8M9PBY0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PBY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBY0/entry#A0A8M9PBY0-1", 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"https://www.uniprot.org/uniprotkb/A0A8M9PBY0/entry#A0AC58J0W5-1", "sequence": { "sequence": "MKQEAAHTDRLITLCLFRNKKQEKSEPTYKNMYVTNKNATLIESDSEGSDQSTQHVEEEWISDAISAADIVSDLSQKIIRTSCSRFNINRANIWDGAVRGFKRASYDPLHDMLVKFTDDEGSTEDAVDTGGPKREFLTLLMDCLKARRIFDGPENGRFLTFNNAAVREDEYFLAGRMIAVSIVHGGPGPRFLSNMLYDYLIGRTDINGTVEDVTDETMKAALIEISSAESLDELHTLIEKYESLLQTAGCFDFPQSVKGKDNIVKDFILWYIIYRNQYSVQRFRDGLSTLDVINALQQHPIAFRPYMCYSVDRLTAVSLEDVFKPQLSEPGSTRRQEETRILGYWRDYLLDTGEQETGVSLQNILMFATGLDSLPPSTIVPQPRLIFERSSKFPIASTCANTIKLPVSKSYDEFKNAMDFGIQNSPGFGLR", "length": 431, "header": "tr|A0AC58J0W5-1|A0AC58J0W5_DANRE Computationally mapped isoform of G2/M phase-specific E3 ubiquitin-protein ligase isoform X3 OS=Danio rerio OX=7955 GN=LOC100536045 PE=4 SV=1 CANONICAL=A0A8M9PBY0-1" }, "locus": {} }, { "isoform_ac": "A0AC58J0W7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBY0/entry#A0AC58J0W7-1", "sequence": { "sequence": "MYCPYCGASLDSCPSFCSKCGKNITFLKGKVPDGNEPSTSGGKTETSSVDCFMKFRAIKEKERKTFFTKKSHASKKDKGVKIYIGSMERHCGVLKPLRGKRLPLEVETNWTSEQVLIAGKKKVKDFNQDMEDGPYVLLYPDGSEVKNIPGTNTPFKLQLYKEAIGKAYQRITLYICTVEDFFATDCNEDSSSEDSVVQVKFTSHSQHDESDTLIWDSADEAGSSSHRPPDHSLPVQEQEAGKIRTNIQEHVRDQQKCYTNYTRLYAPIVIESDSEGSDQSTQHVEEEWISDAISAADIVSDLSQKIIRTSCSRFNINRANIWDGAVRGFKRASYDPLHDMLVKFTDDEGSTEDAVDTGGPKQKIYFPVAVREDEYFLAGRMIAVSIVHGGPGPRFLSNMLYDYLIGRTDINGTVEDVTDETMKAALIEISSAESLDELHTLIEKYESLLQTAGCFDFPQSVKGKDNIVKDFILWYIIYRNQYSVQRFRDGLSTLDVINALQQHPIAFRPYMCYSVDRLTAVSLEDVFKPQLSEPGSTRRQEETRILGYWRDYLLDTGEQETGVSLQNILMFATGLDSLPPSTIVPQPRLIFERSSKFPIASTCANTIKLPVSKSYDEFKNAMDFGIQNSPGFGLR", "length": 635, "header": "tr|A0AC58J0W7-1|A0AC58J0W7_DANRE Computationally mapped isoform of G2/M phase-specific E3 ubiquitin-protein ligase isoform X2 OS=Danio rerio OX=7955 GN=LOC100536045 PE=4 SV=1 CANONICAL=A0A8M9PBY0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100536045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536045", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-protein transferase activity", "id": "GO:0004842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004842", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PBY0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 260, "end_pos": 262, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], 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{ "uniprot_canonical_ac": "A0A8M9PC66-1", "uniprot_ac": "A0A8M9PC66", "uniprot_id": "A0A8M9PC66_DANRE", "mass": { "chemical_mass": 22090.0, "monoisotopic_mass": 22090.0 }, "refseq": { "ac": "XP_021321984", "name": "transmembrane 4 L6 family member 19", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321984" }, "gene_names": [ { "name": "LOC101885866", "type": "recommended", "evidence": [ { "id": "A0A8M9PC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC66" } ] }, { "name": "LOC101885866", "type": "synonym", "evidence": [ { "id": "XP_021321984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321984" } ] } ], "protein_names": [ { "name": "Transmembrane 4 L6 family member 19", "type": "synonym", "evidence": [ { "id": "A0A8M9PC66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC66/entry#names_and_taxonomy" } ] }, { "name": "transmembrane 4 L6 family member 19", "type": "synonym", "evidence": [ { "id": "XP_021321984", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321984" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021321984.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021321984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321984" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC66", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC66" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101885866", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC66", "locus": {} } ], "crossref": [ { "id": "A0A8M9PC66", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PC66", "database": "AlphaFoldDB", "categories": [] }, { "id": "101885866", "url": "https://www.ncbi.nlm.nih.gov/gene/101885866", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885866", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885866", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PC66", "url": "https://www.orthodb.org/?gene=A0A8M9PC66", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14198:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14198:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021321984", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021321984", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PC66", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC66", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PC66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC66-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MYISSRCVGLTLIPTAIISMLANLLLLFPDMKYRYLAKGHVTAEALWCSGIWASGFLVLVAARGFTTHYEKTGCCYFAAEVLRKMGYTCLAILAAGLCFWVSGTGLALGPLCLHNGTQGLKWERPLKLIKTGQTLYLYEPERWASACVEPRGVVIWNLLLFSVLMVASGLQLISCVLHLFIAFLEFMCGPHFCKNKVVPA", "length": 200, "header": "tr|A0A8M9PC66-1|A0A8M9PC66_DANRE Isoform 1 of Transmembrane 4 L6 family member 19 OS=Danio rerio OX=7955 GN=LOC101885866 PE=3 SV=2 CANONICAL=A0A8M9PC66-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PC66-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC66/entry#A0A8M9PC66-1", "sequence": { "sequence": "MYISSRCVGLTLIPTAIISMLANLLLLFPDMKYRYLAKGHVTAEALWCSGIWASGFLVLVAARGFTTHYEKTGCCYFAAEVLRKMGYTCLAILAAGLCFWVSGTGLALGPLCLHNGTQGLKWERPLKLIKTGQTLYLYEPERWASACVEPRGVVIWNLLLFSVLMVASGLQLISCVLHLFIAFLEFMCGPHFCKNKVVPA", "length": 200, "header": "tr|A0A8M9PC66-1|A0A8M9PC66_DANRE Isoform 1 of Transmembrane 4 L6 family member 19 OS=Danio rerio OX=7955 GN=LOC101885866 PE=3 SV=2 CANONICAL=A0A8M9PC66-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885866", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885866", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PC66", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC66" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 115, "end_pos": 117 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PCC1-1", "uniprot_ac": "A0A8M9PCC1", "uniprot_id": "A0A8M9PCC1_DANRE", "mass": { "chemical_mass": 50647.0, "monoisotopic_mass": 50647.0 }, "refseq": { "ac": "XP_021322069", "name": "zona pellucida-like domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322069" }, "gene_names": [ { "name": "si:dkey-4p15.5", "type": "recommended", "evidence": [ { "id": "A0A8M9PCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCC1" } ] }, { "name": "si:dkey-4p15.5", "type": "synonym", "evidence": [ { "id": "XP_021322069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322069" } ] } ], "protein_names": [ { "name": "Zona pellucida-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8M9PCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCC1/entry#names_and_taxonomy" } ] }, { "name": "zona pellucida-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_021322069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322069" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322069.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322069" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCC1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-4p15.5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCC1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-121214-193", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-193", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PCC1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PCC1", "database": "AlphaFoldDB", "categories": [] }, { "id": "562872", "url": "https://www.ncbi.nlm.nih.gov/gene/562872", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562872", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562872", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PCC1", "url": "https://www.orthodb.org/?gene=A0A8M9PCC1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00100", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00100", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322069", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PCC1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-121214-193", "url": "https://zfin.org/ZDB-GENE-121214-193", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVLGTMDFVPDLEKAKVTGSESLSVERSPEGFMLRSSLSSFLSHPKPLYKNPICQICKIEEAYHPDFVDSTDHVMMIRLVQLLCLSGLLLHCEAQGFQSCLADPTFRLADNSDISVTCGTNQMFLRILLCPMYFGGYNESLMALNARFGIPDCRGVADWSSSPPVLMFNFSISQEALLLCGNTINITSQVGSGVFSDFSQIQSVNISGLINAWDPSISAITYRQQLTYQFSCVYPLQYLVNNTEVKVSGVSLAVKDNNGTFVSTLSMTLFTTANYTTKLTIPQTGLQLKTRIYVQVKATNLTNKFNVMLDRCYATTSPYPTSSSSYDLFLGCTRDPQTKVDMNGIAQEAHFSFEAFRFVEHKNLTISTFYLHCATRLCENSTCASLLPKCARKRNVRSIDYNASDVATVSSGPIRTRVDNGGLASRLTSSSSIPQLTYAGAATGLLSVLLLNWLSGSGPAW", "length": 461, "header": "tr|A0A8M9PCC1-1|A0A8M9PCC1_DANRE Isoform 1 of Zona pellucida-like domain-containing protein 1 OS=Danio rerio OX=7955 GN=si:dkey-4p15.5 PE=4 SV=2 CANONICAL=A0A8M9PCC1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PCC1-1", "url": 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"n_glycosylation_sequon" }, { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PCC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCC1" }, { "id": "PS51034", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51034" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZP", "eco_id": "ECO_0000259", "start_pos": 117, "end_pos": 397, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 321 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { 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"uniprot_ac": "A0A8M9PCD7", "uniprot_id": "A0A8M9PCD7_DANRE", "mass": { "chemical_mass": 79299.0, "monoisotopic_mass": 79299.0 }, "refseq": { "ac": "XP_021324383", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324383" }, "gene_names": [ { "name": "LOC110438202", "type": "recommended", "evidence": [ { "id": "A0A8M9PCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7" } ] }, { "name": "LOC110438202", "type": "synonym", "evidence": [ { "id": "XP_021324383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324383" } ] }, { "name": "pfkfb2a", "type": "synonym", "evidence": [ { "id": "A0A8M9PCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7" } ] }, { "name": "pfkfb2", "type": "synonym", "evidence": [ { "id": "A0A8M9PCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7" } ] }, { "name": "zgc:56282", "type": "synonym", "evidence": [ { "id": "A0A8M9PCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021324383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324383" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324383" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCD7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438202", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7", "locus": {} } ], "crossref": [ { "id": "A0A8M9PCD7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PCD7", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438202", "url": "https://www.ncbi.nlm.nih.gov/gene/110438202", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "393983", "url": "https://www.ncbi.nlm.nih.gov/gene/393983", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110438202", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438202", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PCD7", "url": "https://www.orthodb.org/?gene=A0A8M9PCD7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31751:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31751:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021324383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324383", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PCD7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6L8", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6L8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6P1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6P1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6P1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6P1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPPREHPCAILGCKAQHKSLHRLPANEQQRLKWLSFIFEDKVPENVPKLLYVCANHFSVDCLENAGQYNSGFASKLFLKTGSVPTIRDPVSLQATTSTKSNKVDVACQTEPFHTSLHSVGTQLSFRTLQAKRRSTSVQTTVSSFELTVPLASSTAFMTSTPLKPSLKRPRLELEEEEEEEEAEETLTESKIIAQDSDVTFDPAEECTSATEPTDLSIQECPVHNIAKFIVYETCLMELFSDCPVCQRRCDVKSQRLGTFLSVQQVCPHCEFVRKWNSQPIIGSTPAGNLHLSAAVYLSGASFFVVEKVFAAMKLHIFKYNSFRRHARLCIEPAIVHKWRNWQSEMLEQLSRRENVIVGGDMRADSPGHSAKYGSYTMMDLATNTVVDLQLVQSNEVGGSYHMEKEGLKRSLDLLDARGVRLECIITDRHPQIQKYLRDRNVTQFYDVWHIEKGISKKLDKICQIKGCEKLRKWLRSIKNHIYWTAASSTTGPERVAKWTSILNHVQDKHVHEDPNFPACLHPQRISRDKNKWLSAATMPFYKLEKVLANKRILKDVAKLSPHHQTSTVEAFHSVILRFAPKNVVFPFLGMLCRLYLAALHYNENAGRPQATSATGKPIYKLAFPKAKKGEYRVREVKTQQTFGYVEELLDLIFNQVFVDPSPYVDEVLGIHIPPALSSAYDRPEMEEAISSRVTRFNQ", "length": 698, "header": "tr|A0A8M9PCD7-1|A0A8M9PCD7_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110438202 PE=4 SV=1 CANONICAL=A0A8M9PCD7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PCD7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7/entry#A0A8M9PCD7-1", "sequence": { "sequence": "MPPREHPCAILGCKAQHKSLHRLPANEQQRLKWLSFIFEDKVPENVPKLLYVCANHFSVDCLENAGQYNSGFASKLFLKTGSVPTIRDPVSLQATTSTKSNKVDVACQTEPFHTSLHSVGTQLSFRTLQAKRRSTSVQTTVSSFELTVPLASSTAFMTSTPLKPSLKRPRLELEEEEEEEEAEETLTESKIIAQDSDVTFDPAEECTSATEPTDLSIQECPVHNIAKFIVYETCLMELFSDCPVCQRRCDVKSQRLGTFLSVQQVCPHCEFVRKWNSQPIIGSTPAGNLHLSAAVYLSGASFFVVEKVFAAMKLHIFKYNSFRRHARLCIEPAIVHKWRNWQSEMLEQLSRRENVIVGGDMRADSPGHSAKYGSYTMMDLATNTVVDLQLVQSNEVGGSYHMEKEGLKRSLDLLDARGVRLECIITDRHPQIQKYLRDRNVTQFYDVWHIEKGISKKLDKICQIKGCEKLRKWLRSIKNHIYWTAASSTTGPERVAKWTSILNHVQDKHVHEDPNFPACLHPQRISRDKNKWLSAATMPFYKLEKVLANKRILKDVAKLSPHHQTSTVEAFHSVILRFAPKNVVFPFLGMLCRLYLAALHYNENAGRPQATSATGKPIYKLAFPKAKKGEYRVREVKTQQTFGYVEELLDLIFNQVFVDPSPYVDEVLGIHIPPALSSAYDRPEMEEAISSRVTRFNQ", "length": 698, "header": "tr|A0A8M9PCD7-1|A0A8M9PCD7_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110438202 PE=4 SV=1 CANONICAL=A0A8M9PCD7-1" }, "locus": {} }, { "isoform_ac": "A0AC58I6L8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7/entry#A0AC58I6L8-1", "sequence": { "sequence": "MTSTPLKPSLKRPRLELEEEEEEEEAEETLTESKIIAQDSDVTFDPAEECTSATEPTDLSIQECPVHNIAKFIVYETCLMELFSDCPVCQRRCDVKSQRLGTFLSVQQVCPHCEFVRKWNSQPIIGSTPAGNLHLSAAVYLSGASFFVVEKVFAAMKLHIFKYNSFRRHARLCIEPAIVHKWRNWQSEMLEQLSRRENVIVGGDMRADSPGHSAKYGSYTMMDLATNTVVDLQLVQSNEVGGSYHMEKEGLKRSLDLLDARGVRLECIITDRHPQIQKYLRDRNVTQFYDVWHIEKGISKKLDKICQIKGCEKLRKWLRSIKNHIYWTAASSTTGPERVAKWTSILNHVQDKHVHEDPNFPACLHPQRISRDKNKWLSAATMPFYKLEKVLANKRILKDVAKLSPHHQTSTVEAFHSVILRFAPKNVVFPFLGMLCRLYLAALHYNENAGRPQATSATGKPIYKLAFPKAKKGEYRVREVKTQQTFGYVEELLDLIFNQVFVDPSPYVDEVLGIHIPPALSSAYDRPEMEEAISSRVTRFNQ", "length": 542, "header": "tr|A0AC58I6L8-1|A0AC58I6L8_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=LOC110438202 PE=4 SV=1 CANONICAL=A0A8M9PCD7-1" }, "locus": {} }, { "isoform_ac": "A0AC58I6P1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7/entry#A0AC58I6P1-1", "sequence": { "sequence": "MIEEQAEQGQSDVQCQATTSTKSNKVDVACQTEPFHTSLHSVGTQLSFRTLQAKRRSTSVQTTVSSFELTVPLASSTAFMTSTPLKPSLKRPRLELEEEEEEEEAEETLTESKIIAQDSDVTFDPAEECTSATEPTDLSIQECPVHNIAKFIVYETCLMELFSDCPVCQRRCDVKSQRLGTFLSVQQVCPHCEFVRKWNSQPIIGSTPAGNLHLSAAVYLSGASFFVVEKVFAAMKLHIFKYNSFRRHARLCIEPAIVHKWRNWQSEMLEQLSRRENVIVGGDMRADSPGHSAKYGSYTMMDLATNTVVDLQLVQSNEVGGSYHMEKEGLKRSLDLLDARGVRLECIITDRHPQIQKYLRDRNVTQFYDVWHIEKGISKKLDKICQIKGCEKLRKWLRSIKNHIYWTAASSTTGPERVAKWTSILNHVQDKHVHEDPNFPACLHPQRISRDKNKWLSAATMPFYKLEKVLANKRILKDVAKLSPHHQTSTVEAFHSVILRFAPKNVVFPFLGMLCRLYLAALHYNENAGRPQATSATGKPIYKLAFPKAKKGEYRVREVKTQQTFGYVEELLDLIFNQVFVDPSPYVDEVLGIHIPPALSSAYDRPEMEEAISSRVTRFNQ", "length": 621, "header": "tr|A0AC58I6P1-1|A0AC58I6P1_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC110438202 PE=4 SV=1 CANONICAL=A0A8M9PCD7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110438202", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438202", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCD7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCD7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PCD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCD7" }, { "id": "PS50950", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50950" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "THAP-type", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 87, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 440, "end_pos": 442 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PCE2-1", "uniprot_ac": "A0A8M9PCE2", "uniprot_id": "A0A8M9PCE2_DANRE", "mass": { "chemical_mass": 33822.0, "monoisotopic_mass": 33822.0 }, "refseq": { "ac": "XP_021324393", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324393" }, "gene_names": [ { "name": "LOC110438207", "type": "recommended", "evidence": [ { "id": "A0A8M9PCE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCE2" } ] }, { "name": "LOC110438207", "type": "synonym", "evidence": [ { "id": "XP_021324393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324393" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PCE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCE2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021324393", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324393" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324393", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324393" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCE2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCE2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438207", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCE2", "locus": {} } ], "crossref": [ { "id": "A0A8M9PCE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PCE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438207", "url": "https://www.ncbi.nlm.nih.gov/gene/110438207", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052882", "url": 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04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322149" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCI4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110437916", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI4", "locus": {} } ], "crossref": [ { "id": "A0A8M9PCI4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PCI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "110437916", "url": "https://www.ncbi.nlm.nih.gov/gene/110437916", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": 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{ "uniprot_canonical_ac": "A0A8M9PCI8-1", "uniprot_ac": "A0A8M9PCI8", "uniprot_id": "A0A8M9PCI8_DANRE", "mass": { "chemical_mass": 125443.0, "monoisotopic_mass": 125443.0 }, "refseq": { "ac": "XP_009290195", "name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290195" }, "gene_names": [ { "name": "si:dkey-121n8.7", "type": "recommended", "evidence": [ { "id": "A0A8M9PCI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI8" } ] }, { "name": "si:dkey-121n8.7", "type": "synonym", "evidence": [ { "id": "XP_009290195", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290195" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_009290195", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290195" }, { "id": "A0A8M9PCI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009290195", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290195" } ] } ], "disease": [ { "disease_id": "DOID:0050854", "recommended_name": { "id": "DOID:0050854", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "Muckle-Wells syndrome", "description": "A syndrome characterized by episodic skin rash, arthralgias, and fever associated with late-onset sensorineural deafness and renal amyloidosis that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q44." }, "synonyms": [ { "id": "DOID:0050854", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "MWS", "description": "" }, { "id": "DOID:0050854", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "neutrophilic urticaria", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle-Wells syndrome", "description": "An intermediate form of cryopyrin-associated periodic syndrome (CAPS) and is characterized by recurrent fever (with malaise and chills), recurrent urticaria-like skin rash, sensorineural deafness, general signs of inflammation (eye redness, headaches, arthralgia/myalgia) and potentially life-threatening secondary amyloidosis (AA type)." }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle-Wells syndrome", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "neutrophilic urticaria", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "MWS", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle Wells syndrome", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "urticaria, deafness and amyloidosis", "description": "" }, { "id": "MIM:191900", "resource": "MIM", "url": "https://www.omim.org/entry/191900", "name": "Muckle-Wells syndrome", "description": "Muckle-Wells syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050854", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050854" } ] }, { "disease_id": "DOID:0080208", "recommended_name": { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol." }, "synonyms": [ { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "nonalcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "non-alcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "NAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-related steatotic liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MASLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic-associated fatty liver disease", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "NAFLD2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "fatty liver disease, nonalcoholic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "liver disease, alcoholic, susceptibility to, 1", "description": "" }, { "id": "MIM:613282", "resource": "MIM", "url": "https://www.omim.org/entry/613282", "name": "Non-alcoholic fatty liver disease 1", "description": "Non-alcoholic fatty liver disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ] }, { "disease_id": "DOID:0080270", "recommended_name": { "id": "DOID:0080270", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080270", "name": "autosomal dominant nonsyndromic deafness 34", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q44." }, "synonyms": [ { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "hearing loss, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "DFNA34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "autosomal dominant nonsyndromic deafness 34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "deafness, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MIM:617772", "resource": "MIM", "url": "https://www.omim.org/entry/617772", "name": "Deafness, autosomal dominant, 34, with or without inflammation", "description": "Deafness, autosomal dominant, 34, with or without inflammation" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080270" } ] }, { "disease_id": "DOID:0090029", "recommended_name": { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "CINCA Syndrome", "description": "An autoimmune disease characterized by neonatal onset of cutaneous symptoms, chronic meningitis, and joint manifestations with recurrent fever and inflammation that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q." }, "synonyms": [ { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "IOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "NOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic infantile neurological cutaneous articular syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "Chronic Infantile Neurological, Cutaneous, and Articular (CINCA) syndrome is characterized by skin rash, joint involvement, chronic meningitis with granulocytes and, in some cases, sensorineural hearing loss and ocular signs." }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA/NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Neonatal-Onset Multisystem Inflammatory Disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic infantile neurological cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal onset multisystem inflammatory disease", "description": "" }, { "id": "MIM:607115", "resource": "MIM", "url": "https://www.omim.org/entry/607115", "name": "Chronic infantile neurologic cutaneous and articular syndrome", "description": "Chronic infantile neurologic cutaneous and articular syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090029", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090029" } ] }, { "disease_id": "DOID:0090062", "recommended_name": { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "familial cold autoinflammatory syndrome 1", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP gene on chromosome 1q44." }, "synonyms": [ { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "FCAS1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "Any familial cold autoinflammatory syndrome in which the cause of the disease is a mutation in the NLRP3 gene." }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "NLRP3 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP3", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome type 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold inflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "FCAS1", "description": "" }, { "id": "MIM:120100", "resource": "MIM", "url": "https://www.omim.org/entry/120100", "name": "Familial cold autoinflammatory syndrome 1", "description": "Familial cold autoinflammatory syndrome 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090062", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090062" } ] }, { "disease_id": "DOID:0090063", "recommended_name": { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "familial cold autoinflammatory syndrome 2", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP12 gene on chromosome 19q13." }, "synonyms": [ { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "An autoinflammatory disease caused by mutations in the NLRP12 gene. It is characterized by periodic fevers beginning in the first year of life that are triggered by cold exposure. Episodes occur more than once per month." }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NALP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NAPS12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome type 2", "description": "" }, { "id": "MIM:611762", "resource": "MIM", "url": "https://www.omim.org/entry/611762", "name": "Familial cold autoinflammatory syndrome 2", "description": "Familial cold autoinflammatory syndrome 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090063" } ] }, { "disease_id": "DOID:12351", "recommended_name": { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "alcoholic hepatitis", "description": "" }, "synonyms": [ { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic hepatitis", "description": "" }, { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic liver disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12351" } ] }, { "disease_id": "DOID:1555", "recommended_name": { "id": "DOID:1555", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1555", "name": "urticaria", "description": "A skin disease characterized by skin rash notable for pale red, raised and itchy bumps, located_in the upper dermis." }, "synonyms": [], "unlinked_id_list": [ "DOID:0060220" ], "evidence": [ { "id": "1555", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1555" } ] }, { "disease_id": "DOID:3590", "recommended_name": { "id": "DOID:3590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3590", "name": "gestational trophoblastic neoplasm", "description": "" }, "synonyms": [ { "id": "DOID:3590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3590", "name": "gestational trophoblastic neoplasia", "description": "" }, { "id": "DOID:3590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3590", "name": "hydatidiform mole", "description": "" }, { "id": "DOID:3590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3590", "name": "molar pregnancy", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "hydatidiform mole, recurrent, 1", "description": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the NLRP7 gene." }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "NLRP7 complete hydatidiform mole", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "complete hydatidiform mole caused by mutation in NLRP7", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "hydatidiform Mole, recurrent, type 1", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "hydatidiform mole, recurrent, 1", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "HYDM1", "description": "" }, { "id": "MIM:231090", "resource": "MIM", "url": "https://www.omim.org/entry/231090", "name": "Hydatidiform mole, recurrent, 1", "description": "Hydatidiform mole, recurrent, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "3590", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3590" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:9452", "recommended_name": { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes." }, "synonyms": [ { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Fatty change of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Steatosis of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "alcoholic fatty liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic lipidosis", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "SLD", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "fatty liver disease", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "fatal neonatal hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-121n8.7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PCI8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PCI8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "108179098", "url": "https://www.ncbi.nlm.nih.gov/gene/108179098", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PCI8", "url": "https://www.orthodb.org/?gene=A0A8M9PCI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009290195", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290195", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HDR2", "url": "https://www.uniprot.org/uniprotkb/A0AC58HDR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HDR2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HDR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-366", "url": "https://zfin.org/ZDB-GENE-070912-366", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEDTQTTIEKDYSPRFSLVHQKRSEPSCVSIRRDQSVAHPIDFKSEDTQTHLSSVHQERLDPEPSCVSIRSDRSVAHPIDFKSKNTHLSSVHQERSEPEPSCVSIRSDRSVAHPIDFKSEDTQTHLSTFHQKRKEADPSCVSMRSDTFMNQPINIKIGETQNDLKQNLLNTFRSNLLKKFECLYEGTAVQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQNKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSEKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCLNNNRNEFEQISKQSLWSKVRDHFHFNSSKLVSISKLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQGLMKLKIRSIQNNETVEYIKKKIRKINFPEKFINLFHCLNELGDHSLVEEIQQFLKSGGMNEAKLSSSQWSAVVFVLLTSEKKLEKFDINEFAARNNNTEQLFIFKKLQPVIRQCRSVQLSYCGLTDEGCAALASALRSNPEHLRDLYLSGNKLGDSVSLLSGVLEDPHCKLETLWLSDCGLTSKDSAALASALRSNPEHLRVLDLSWNRLGDSVTLLSAVLEDPHCKLETLLLRDCGLTDEGCAALASALRSNPEHLKHLDLSWSNLGDSVTLLSAVLEDPRCKLEKLGLSNCGLAEEGCAALASALRSNPEHLRGLNLSVNNLGDSVTLLSAVLEDPRCKLEKIKLSYCGLTDEGCAALASALRSNPEHLRDLDLSTNNLGDSVTLLSAILEDPHCKLEKLELKNCGLTDEGCAVLASALRSNPEHLRDLNLSWNNLSNSTKKLLSDLKDDPHNKLETLHTSLSV", "length": 1115, "header": "tr|A0A8M9PCI8-1|A0A8M9PCI8_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-121n8.7 PE=4 SV=1 CANONICAL=A0A8M9PCI8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PCI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI8/entry#A0A8M9PCI8-1", "sequence": { "sequence": "MEDTQTTIEKDYSPRFSLVHQKRSEPSCVSIRRDQSVAHPIDFKSEDTQTHLSSVHQERLDPEPSCVSIRSDRSVAHPIDFKSKNTHLSSVHQERSEPEPSCVSIRSDRSVAHPIDFKSEDTQTHLSTFHQKRKEADPSCVSMRSDTFMNQPINIKIGETQNDLKQNLLNTFRSNLLKKFECLYEGTAVQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQNKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSEKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCLNNNRNEFEQISKQSLWSKVRDHFHFNSSKLVSISKLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQGLMKLKIRSIQNNETVEYIKKKIRKINFPEKFINLFHCLNELGDHSLVEEIQQFLKSGGMNEAKLSSSQWSAVVFVLLTSEKKLEKFDINEFAARNNNTEQLFIFKKLQPVIRQCRSVQLSYCGLTDEGCAALASALRSNPEHLRDLYLSGNKLGDSVSLLSGVLEDPHCKLETLWLSDCGLTSKDSAALASALRSNPEHLRVLDLSWNRLGDSVTLLSAVLEDPHCKLETLLLRDCGLTDEGCAALASALRSNPEHLKHLDLSWSNLGDSVTLLSAVLEDPRCKLEKLGLSNCGLAEEGCAALASALRSNPEHLRGLNLSVNNLGDSVTLLSAVLEDPRCKLEKIKLSYCGLTDEGCAALASALRSNPEHLRDLDLSTNNLGDSVTLLSAILEDPHCKLEKLELKNCGLTDEGCAVLASALRSNPEHLRDLNLSWNNLSNSTKKLLSDLKDDPHNKLETLHTSLSV", "length": 1115, "header": "tr|A0A8M9PCI8-1|A0A8M9PCI8_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-121n8.7 PE=4 SV=1 CANONICAL=A0A8M9PCI8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HDR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI8/entry#A0AC58HDR2-1", "sequence": { "sequence": "MEDTQTTIEKDYSPRFSSVHQERLDPEPSCVSIRSDRSVAHPIDFKSKNTHLSSVHQERSEPEPSCVSIRSDRSVAHPIDFKSEDTQTHLSTFHQKRKEADPSCVSMRSDTFMNQPINIKIGETQNDLKQNLLNTFRSNLLKKFECLYEGTAVQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQNKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSEKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCLNNNRNEFEQISKQSLWSKVRDHFHFNSSKLVSISKLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQGLMKLKIRSIQNNETVEYIKKKIRKINFPEKFINLFHCLNELGDHSLVEEIQQFLKSGGMNEAKLSSSQWSAVVFVLLTSEKKLEKFDINEFAARNNNTEQLFIFKKLQPVIRQCRSVQLSYCGLTDEGCAALASALRSNPEHLRDLYLSGNKLGDSVSLLSGVLEDPHCKLETLWLSDCGLTSKDSAALASALRSNPEHLRVLDLSWNRLGDSVTLLSAVLEDPHCKLETLLLRDCGLTDEGCAALASALRSNPEHLKHLDLSWSNLGDSVTLLSAVLEDPRCKLEKLGLSNCGLAEEGCAALASALRSNPEHLRGLNLSVNNLGDSVTLLSAVLEDPRCKLEKIKLSYCGLTDEGCAALASALRSNPEHLRDLDLSTNNLGDSVTLLSAILEDPHCKLEKLELKNCGLTDEGCAVLASALRSNPEHLRDLNLSWNNLSNSTKKLLSDLKDDPHNKLETLHTSLSV", "length": 1079, "header": "tr|A0AC58HDR2-1|A0AC58HDR2_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X2 OS=Danio rerio OX=7955 GN=si:dkey-121n8.7 PE=4 SV=1 CANONICAL=A0A8M9PCI8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JW23-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPATAKDALHRLSTYLEELEAGELKKFKLYLGIAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGEDLVRVTPSNGLCSLESQSTCLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGPWCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTSRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFTAMYCALHGREAVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAEDGPPEPPGAQTQSTHSQERNILPDIYSAYLSATICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIANRNLIRLDLSGNSIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSNNSHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVNTCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGISQTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFGMDLNKVTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1PS14-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:dkey-222h21.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNMLQRIKNQHKTSLKNKYERLFEGIEVKETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPENLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGIDVSDASVYSGICTEILKEESVIQQRKVYSFIHLSFQEFLAAFHVFYHHITCSTEASLDSLHDLQKRIINKSTESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKRSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELKLQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITPGLRKYACVLTLDPNTAHTHLVLSEKNRQARNVTDPQPYPDHPDRFKNNEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYSCDTIYTVWHNNKSADIIAPSACTNRVGVYVDVPSGSLSFYSVTDTHTLTLIHTFNTTFTEELYTGFGIYPEASVSLCQI", "length": 892 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RJ47-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "si:ch211-201o1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSAEKSDDAPATGSSPEDLQAEQHEQKKSDSSTVSHVSMKSGRSITPPLDFRKDEQGNTERAKQERAESSTASHLSMKSDRSITPPLDFISGEQKQTERKSVDDHAVSTSADRVCQRHHRALDVFCQTDNIHICCICVEEEHQGHRKTYTAKLNVPDSQSMLLHIMEKMRSEDFNTFKRELSEDYAGCLGAQSEELSVSEAAENIMRSFGGEAALRLILHFQTKANPLKKITDANKTKLKNKCQNINEGNSSYGKQSLLMEVYTDLYFTEGGSGEINNEHEVLRNEMISQSRTTQEVLYACDEIFKTLPGQRTQVRTVLTMGIAGIGKHVSVQKFILDWAEGKANQDIEIIIHLPFRDLSCREESCSLLQLVHQYSPELREADLQHLKVLFILDGLELCQYPLHFHKNVYCADINEKVPVDALLTNLIKGNLLPSALLWITTRPSTAGRIPPECVHRVTEIRGFSDDQKDSYFRKKISDQTLADEIIRHIKSCQSLYIMCHMPIFCWISATVLENIMREGQSEELPRTLTGMFTHFLLLQVSLKHKKFNGADGDNPKKLSEFDQTFILKLGELAFQQMEKGDLIFREEDLREGGIDVSKVSEYSVCTEFFREELGLYREKLYGFLHVSYQEFLAAIYAHFTCVNDGRNVFLKDESRSSVDLCDVHQTAVEKALQSENGHLDLFLRFLLGLSVDSNFNLLQDLLKDTSCKPRVDTSSTVSFIKEKVKLEQSPERIINLFHCLNQLNDNSLVEEIKAAMKSGTLLGSELDPEQWSALAYVYLTSGEEIEEFDMIKSNQLRLLPVLRICKKARLNCCNLSFASCGLVASALKSVNSPLTELDLSNCKLNIFGMNTLLDGLKSPHSKVKKLRLAGCFFPSETCANLALALKSVNSQVTELDLSYNKITDGVHKFCAGLTSQNCKLQKLVLKRCGLTKASCAHLASVLKSNTHLMELELKGNDLQDSGVELLSTGLMDPQCRLEKLGLSGCMITKVGCNSLASALTSNADCMSELDLTYNHPGDSGVKLLTAKKEDPNCKLEKLHVKKRGECRMKPGLRKYACQLTVDPNTIHPRLIVSNDNRTISETTEHQKYPVHPDRYTLYPQAMCREPLADRSYFEVKCTGGVSIGVAYKTSDRTEDLMGFNNTFPSLMCLNGRIKLWQNNDVIHYELPVFAQSSRVGVYVDQYQGSLSYYSICKDTLIHLHTHHTEFTSPLYIGFLFMPDSSVTLLDDSL", "length": 1231 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AHM3-1", "protein_name": "Uncharacterized protein si:dkey-23k10.3 isoform X1", "gene_name": "si:dkey-23k10.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVFLHTTHLYSGQTEVSGYKSTVLRSFVRPSYILKFERNCYHEFSRIHLLSTLLQWQVNLETLRFSACGITDEACFALAKALTSKLSHLRELDLSENKLGDAGVMVLSAALENNCSDLVSLKMNDCDLTYEGCSHLASALASNPSHLRELDLSKNKLDDVEMLVLAAGLENSSCKLEKLRLVKCGLTDEGFVVLNKALRSNPSHLKELDLSENSLCYLHTMLLSSVLESPYWELKTLKLVNCSFTEEGGAALMSALRSNPSHLRELDLSKNNIGYLTMMVLSSAMEIPYWELEILRLNDCGITDDGFAALGAGLRSNPSYLRELDLSKNKLGEFGVHMLSIALEMPYCQLETLRLVSCDITGNGWIVLVSALRSNPSHLRNLDLSGNNLECFEIKLLSEVLESPYCKLETLKLRNCNLKDEECVSLASALRLKISKLRELDLSENKLGDSGVKAFFAELEGHLSKFDALRFVNCGLTDEGCGVLASVLSSNPSHLKELDLSGNKVEDSGVKMLSDGLEDYCCRLETLKLVGCGLTDEGCASLASALTSNSSHLRVLDLSKNKLSDSGVRLISTGLENPHCKVEILWLVDCDVNDEGCAALASALTFNFSNLRELDLSENNLGDFGVKLLSAGLEDPHCKLEILKLKNCGFTDGGIAALAPVLGSDHSYLKNVDLSGNKFEDFGVQLLSIAFY", "length": 692 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3ANC0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch73-168d20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSRKRRSSSPESSCVSIKSDASMDNPPTLRLGESPAKHRRSSSLGSSCVSMKSDASMDNPPTLRLGESPAKHRRSSSPESSCVSMKSDASMDNPPTLRLGESPAKHSDNQKRSQSNKGQKQLDAIFKDLEETNIDEMRKVLRRFKMLLSPDYSVRDEEEEEGQRQINEAFLKITLHALQKMNQTDLASKLQTKLISVSQQQLKSRLKQRFERFTEGVSNRGNTKLLNDIYTEVYITEGGAGNIDDEHEVRQIETSSSRFPEIPIRCCDIFKSLLGQDKAIRTVLTKGVAGIGKTASVQKFILDWAEGKANQDVHFIFPLPFRDLNLIKEKRMSLMELLCCFCPELKPIDYNNFKTVFIYDGLDEWRLPLDFRNNEILWDMNKVASVDALLTNLLQGNLLPSAVHWITTRPAAACQIPAEFIDRVTEVRGFKDLQRAEYFWKRIKDQNLANKIITHIQSSRSLHIMCRIPVFCWISATVLEKIFGEANSADIPKTLTQMFIHLLIVQTNLKTQKYDRECDVNLEKARKSILSLAKLAFEQLEKGNLIFYEEDLKQCGIDVREASVCSGVCTQIFREEFGLQLQKVFSFVHLSVQEFLAALFKFLSFAEENNKSSMTQFMKNEVDRALQSPNGHLDLFLRFLLGLSLDSNQTLLQGLFTPLDTSHSRDETIEYIKSKIRENPSPERSINLFYCLNELNDHSLVQEVQTYLTSTRSHRLSGVKLSPALWSALVFVLLNSTKDLDEFELRQYDFTEECLLRLLPVVKASRKADLKGGNLTDQICSALASALSSSSCCLRELDLSENRLQLSGIRLFSAGLKSPNCKLEILKLSNCSIREEGCASLVSALLSNPSHLRELNLNSNQPGYSTVKLLSDLLENPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLNGSNIREKDCAAFISSLLSNPFHLRELSLSWNKPGDSGVKLLSDLLKDSRCKLEKLELECCSIIEEGCAALALALVSNPSHLRELNLNNNEPGDLGVNLLSFLLKNPQCKLEKLELEYCCIGAKSCASLASAFVSNPSHLRELNLNWNTPEYPAVKLLSDYLKDPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLEYCCIGEEGCAALVSGLKSNPSHLRELNLNRNEPGNLGAKMLSDLLKDPLFELEKLELDDCSIENNGFADLVSGLKSNPSNIRELNLNSNKFIFSGLNLLCDLLRDQQCKLRKLQLECCNIDEEGCAALALALISNPSHLRELNLNYNNPGGLGVKLLSVLLKNPHCKLEKLELSHCSISENYLAALNSALSSNPAHLRELNLNYNENTRQ", "length": 1388 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQ59-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKIFQNLTAESGKGIRDYVVQIRFCFIMDDTQISRDENVSPGCSSVHQKRSDPEPSCVSMRSDWSMDPPISFKSKDTPPDFSSVHQKSTESEPSCVSMRSDDESVDQPLHVRSGDTETDLSHEALNTFRSDLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIIPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLMNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHLLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDGFEEIKKPSLWSKVKDLLYLNSSQLVSLSELHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQIILQRLMILKSRSIQINKTVEYIKMKIRTIDSPEKFINLFHCLNELGDHSLVEEIQQYLKSGRINRAKLSESQWSAVAFVLLTSEKKLEEFHINEFVGETEKIFIFMKLLPVIRECRSVQLNNCGLTDEGCAALASALRSNPEHLRELNLSGNRLGDSVTLLSALLEDPRCNLEILWLSYCGLTDEGCAALASALRLNPEHLRELNLSHNNISKSTVKLLSDLKHNPHNKLETLYI", "length": 837 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B0M3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "si:dkey-7i4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESDEQHNDTLVQMGSSGNSGINADLRAEKEATVIAPLLNGNNITGPVTFNYCSNSAENEPQKYPKTADKHTEKQDDLKLQKILETHRTYMKKKVDCILDCTKENAEHFKAFYTELFIAEGDMQDVNQEHEILKIDDAFKKKKASLRSIRCKDIFAELKAKSEKNTVLTKGIAGIGKTVSVRKFILDWAEGQTNHDIHCVFLLPFREINLMTNEDFNLHEFLLKFYPELKELETSVLFQQCNLAFIFDGLDESRLPLNFKSRTLNNVEERSSVDMLFTSLVKGNLLPSALVWVTSRPAAANQIPPRYVGLFTEVQGFTDQQKEKYFRNRIADETQASKIISHIKTSRSLYIMCHIPVFCWITATVLQDILQRNIESIGTTLTEMYIHFLLIQMNMKSQKYDPEEEREYAKLLEANREVILKLAKLAFEQLKKENVVFYEQDLKDCGIDVNVEFTGMIAEIFKVEHGLHEAKVFYFVHLSVQEFLAAVYVFFCFLNRNTHELTFFFESSQNTPRELQFLFKKTFRKVKFHDLIKRATDKAMRSKRGHLDLFLRFLLGISLESSQNLLKGLFSHVIDTTRSIKKISPHFKHLQNKNISCDCSVNLFFCLLELKDHSLYEEIQRSLNSDRRPSKELSSSMCTVLTYIVLMSEKELDELNPKRFTSSQENYRKLVPAVRCCRKALFNGCGLDEMSFQTISSALQSSDSYLTELELSNNHLQDSGVKLLSDGLKSSHCQLNILRLCGCGLTDQSCESLSSALQSSNSVLRELDMSNNMLKDSGVKLLAVALKSLNCKLERLRFSMCNLTAESCESLSSVVELSNSVLRELDLSNNDLQDSGVKLLSDGLKRNCRLEILRLSGCMVTEVGCGFLSSALSSTTSTLRELDLSYNHPGDSGEKLLSDAHNQPNCRLCVDHGGEFRLTTGLHKYARFFTLDPNTANARLILSEENRKVTCVRKKQPYPDHPDRFEGYLQVLCRESVCGRSYWEIEWTGVVFISVSYSSIGRMGSDKECWFGFSNQSWSLFCSSDRCSFTHSSTEIDLPVKHTSSRIGVYVDHSAGTLSFYSVSDTVSLIHSVQTTFTQPLHPGFYISLGSSVKLC", "length": 1096 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YSM0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch211-181d7.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSHKQTLKYFSPVCSSVQQERSDSAEPSSVSVKSHWSIDPPPQMTERRDSLSLALQERSDSPEPSHVSMKSDWSIDPPPQMKEENRSLVQQERSPKSSCVSMKRDWSIDPPPQMNDEDGQKRLSLVQQERSDSAEPSLVSMKSDWSIDPPPQMKDGDRQKSLSLVQQERSDSPEPSHVTMKSNWSIDPPPQMTDRRDSLRQIPRPRPGAEEPISKKMKYDESVIKSQECMENPSLIFSHEVNTFRVNLLKKFQCLYEGMVTQDNPALLNEIYTELYITESESGEISNEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPETKEIDIFSDKYKILFIFDGLDECRLLLNFKSNEILQHVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLMAQINTKDMKYTGKKDKDMIFKLGKLAYEQLERGNVIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFIHLSVQEHLAALYVHLLFTNHNRNVFEQMTKKTSKTLDILDCFHSNSPENVLLSELHQKAVDEALQSKNGHLDLFLRFLLGLSLESNQILLQELMIKFRSSSDSSEKTVEYIKKRINNICLPEKSINLFYCLNELGDHSLVKEIQQYMDYGTLAETKISCGQWSALVFILLTVEQAMDVFELNKFIGLKKSSDEVLRKLLPVIKKSRSAIMDDCNITAEGCAYLASALGSNPSYLRELDLSANKLQDSGIKKLSKGLQDSHCKLEKLNLYHCGVTNEGCAALASALKSNPEHLRDLNLSENKIGNLGLTCLSEILKNSLCKLEILRLCQCGITDCTDLASALISNPEHLRELELSLNKIGDSGVTALCAAFEDPRFKLEKLGLSGCGLTDEGCAALTSALRSNHEHLRDLDLSGNKVDKEVKGSILQRILEKLNNIQILSV", "length": 1068 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YU37-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch73-24k9.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDNQTFSDAPVCSNESNPEFEPSCVSMKSDQSMDPPMKFKEGHTSADLSDRLNPPGSSCVSMKSDWSMDRPIQFKEEHSSADLSNKSNPGEPSCVSSKSDQSMGPPINVMEEHSAADLRLDPHLKQNGLRSNLLRKFQCLYEGTAMQGDPTLLNEIYTELYITESDSGEINNKHELRQIETRSRRSATEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEEKENQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEQFKVLFIFDGLDECRVSLDFKCDVKLHDVSESASVDVLLTNLIMGNLLPSALIWITSRPAAADLIPSEFVHRVTEIRGFNDPQKEEYFRKRIRDQFLADIIIINLKSSRSLHIMCHIPVFCWISATVLEKIFSQAQSGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEVRDEDMILKLGKLAFEQLVKGNLIFYEEDLRECGLDVTEASVYSGLCTQIFREEFGFYQGKVFCFVHLSIQEHLAALYAHHSLTNKNRNVFKQTKPSLLSKVLNQKKHDSLSVLHQRAVKEASQSKNGHLDLFLRFLLGLSLESSGTLLRELLTQTGSCSYNKEETVQYIKQKIRENRSPERSINLFHCLNELGEDSLMQEIQDYLSSGEIKETKLSSSQWSALVYVLLTSEKKMDFFDLSKFIGPQLRADVVLQKLLPVVKESRSVRLGDCKVTDKVCAALASALRLNSSHLTQLDLIGNKLGDSGVKLLSDGLKDPHCKLKNLMMRDCGVTDEGCAALASALRSNSTHLTELNLNENNLGDAGVKRLSDGLKGPHCKLEILRLWRCGVRDEGCAALASALSSNSTHLKELELSDNKLGDSGVKLLSDALKDPHCKLEKLRLNGCGVREQGCVSLALALRFNPSSHLTELDLTSNELGKSGVKLLSDLRDDPRYKLRHLACDMFGRIIVSSGGGRLDELLPTTSTET", "length": 978 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkey-165e24.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHRVRSGSCVSSSVSLKSDCSKEDPPKFSEKTPSSAQSVRSGLCVSSFVSLKSDCSKEDPPKFSEKTPSSAQSDEDELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNELEKFKQILQEENRQEFVKDYNENRSRITEAALDLTLFFLREMKQDHAADTLQDELLFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAVSRRHQSLETQVEFKHLFKAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQLFPETKGLNLTRSTQFKVLFILDGLDECRLPPNFAGNEMCCDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILNLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSQGKLAFQQLERNNVIFYESDLNDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEGIIAYIKQKLEGNLSPERSINLFYCLSELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELWKFQRSDECLIRLSAIIKNSKRALLQSCNLTVQSCKSLSSILQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLATCNLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSEHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDTLNLDHVGDMRITAGPRKYVCFLTLDPNTANTQLKLSKENRKVKHVREDLRIMRKDRRYPYHPDRFDPVFQVLCRESVCGRCYWEIDWSGDHGVFISVSYKSIRRKRGDACEFGCNAQSWSLLCLSSRFTFRHNNTHTHVPVKPLSRRIGVFVDHSAGTLIFYNIYKDTMSLIHSVQTTFTEPLCPGFGFYSGSSVKLS", "length": 1137 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1F5-1", "protein_name": "Protein NLRC3", "gene_name": "si:dkey-23k10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METEGPDSPEPSCVSLRSDHSKAHHVLFKDEDPFEYSSGQTGRSSPTPSHVSLASNMSINQPLEFKSCSNTLLLKEIQEAIQSVLRIRFQCLHEGLSKHSVLIPLNDIYTELYITEGEGGELNNEHEIRWIETACRRALTEDRPVNLNDIFKPLHGQDRPIRTVLTKGVAGIGKTVSVQKFIIDWAEGEANQDIWFIFPLPFRELNLLKDQSFSLKGLLQYFMNIELDISLHEGKIMFIFDGLDECRLPLDFHNNVKLCDVTESASVDVLLTNIIRGNLLPSSLIWITSRPAAADVVPSKCIHRVTEVRGFSDPQKEEYIRKKVSDQTLSDRIISHLKSSRSLYIMCHIPVFCWISATVLKKMLSEAESAEIPNTLTQMYTQFLMLQLRIKNEKAYDKKSSDIDIVLKLGELAFQQLEKLNLIFYKEDLREYGIDEQEASVYSGLFREESGMFQGKVYSFVHLSVQEHLAALYVYLYFVNENINKLNQPNFLTSILKCVPTVFDVYQTAVKKALQSTSGHLDLFLRFLLGFSLESNQNLLGDLQVQTESSSDSREQIVGFIKEKIKESPPPEKMINLFHCLNELNDHSLVEEIQDFLQSESRINMKLTASQWSAMVFVLLTSGQKLDVFDLNKYIGTYILPDESLQRLQPVLAASRTAKLCEHNLTKRGYSVLVSVLTSKTSCLRELNLTRSAVNDSGLKLLCSGLENPQCKLETLRLEFCGVSDKGCDFLASALRSNPSHLKALDLSGNTLNFTGLKNLLAEFQKPHCKLQRLCLRLCGLTDVGCDALASVLRSDPSHLTELNLSGNKLGDLGMKLLAGGLQNPHCKLQILRLGDCSITHEGCAALASALRSNPSHLRELDLSGNKLNNAGVQILSGELENPDCNLEILRLENCDVGEEGCAALAEALKSNPLTLKELDLCWNKLGNSGVQRLCTSLENPNCTLGVLRLTGCNISENGCAALASVLRSNPSYLRDLDLSHNDLRSSGVRLLSSALEKPDCKLEILRLEYCKITDDGCAVLASALKSNPSHLRELYLYMNSFNLTASGRQLLSKIKDDPHYKLQTLHYESHFFC", "length": 1074 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z5L8-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch211-207e19.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKDFNENRSRITDAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTDHEIRQIEAASRRHQSLEIQVECKHLFEAAEQHEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETEGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVDKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKKQGWFFIQISKNKGMIDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKGEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSADLSPAQWSALVFVLLTSEEELEVFELQKFQRSDECLIRLSAVIKTSKRALLQGCYLTVRSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLQFCNLTVQCCESLSSALQSSNCVLRELDLSINDLQDSGVKKLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKYVCFLTLDPNTAHTELILSEENREVKSVRENQPYPDHPDRFDYYHQVLCRESVCGRCYWEIDWSGDGVVCISVSYKSIRRKGGGDECVFGYNAQSWSLRCDSSRFKFWHNNTHTDLPVEALSSRIGVFVDHSAGILIFYNIYRDTMSLIHSVQTTFTEPLCAGFRVYYPGSSVKLS", "length": 995 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PLT8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "nlrc8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSMNHPKHFKSGETQNDLGSAHQKRSDPEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQKRSDPEPSCVSMKSDWSMDPPMQFKSKDTPPDLSSVHQERSEPEPSCMSMNSDLPLDPPIRYKSGETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQSLWSKTKFMFKTVALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLKLKRRSIKNNKTVEYIKKKIRTIDSPEKSINLFHCLNELGDHSLVEEIQQYLKSGGINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAENNKTEKLVIFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTLLSAVLEDPHCKLEKLWLSYCGVTDEGCAALVSALRSNPEHLRELNLSGNNLGDSVTLLSAVLEDPHCKLEKLRLYYCGLTDEGCAALASALRSNPEHLRDLDLSWNKLGDSVTLLSAVLEDPRCKLEKLELYNCGLTDEGCAALASALRSNPEHLRDLNLSGNKLGDSVTLLSAVLEDPRCKLEKLWLSDCGLTDEGCAALASALRSNPEHLTELDLSWNNLSKSTVRLFSDLKDNPHNKLKTLHI", "length": 1017 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPT2-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSKRKREDEDAASEISSASPGSSCVSVKSDQSMKKNLPDFSDASVTSDLSISKTINQRSASPEFSVLSMTSNRSIGQPENFSDEPVTFDSVLSDALDKPDYEKLHRIKDQHKTSMKNKYERLFEGLKLDETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHRASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFHVFYYHVNTTMDGLRNFASVENLIKGAVDKAIESENGHLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLFREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCGIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTRQKLNWDHGGHFRITPGLRKYACFLTLDPNTAHNQLILSEDKRKVTHVKDPQQYTDYPEKFVHQEQVLCKETLTGRCYWEVEWSGEGTDIAVAYKGIRRKAGSDCWFGYSEKSWSLFYTGNGFNVWHNNKSQIIPAPSPLSNRVGVYLDTESGSLSFYSVSDTHTLTHLHTFNTTFTEPLYAGFRVFDSSLSLCNI", "length": 993 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PSD3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEEQGKMSLSEKHSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKPMSAKSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKQTSAKSVISDSCVSGSVFVKSDCSKDGDLPNFSEETPSSGKSFEHKTSDSDFQTHRKHKGFQDGLLGIFQDLENQIMNYLKHELEKFKKILQKENIIDFVKDFNENRCSIKEAALDLTLYFLREMKQEESADTLEDELIFIHQLKCGLQKKYQCVFEGIAQQGDSRLLKNIYTDLYITQGGSEQVNTEHEVRQIEVASRRHEAQELQVECRHLFEASEQDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQEISFIFPLPFREMNLKEKETLSLMELITQFFPETKGLNLTRRNRFKVLFILDGLDECRLPLNFAGNETCCDVSSPASLDVLLTNLIKGNLLPSALIWITSRPAAASKIPPDCIDRLTEIRGFNDAQKEEYFRKRLTDENQAKEIIDHVKQSKSLFIMCHIPVFCWISATVLQNILQEKRNNDVKHNQADDASKTLQESNTEDTPKTLTQMYTHFLRFQIQQSRRKYNGEYTPDVSWDKDAILSLGKLAFHHLLNNNLIFYDTDLEACGIDVYKASVYSGMCTQIFKEETGIILGTMYCFVHLTLQEFIAALYAHLILDTNKKSVFDQDSKKINESMIDLLKTAVDKALESDNGHLDLFLRFLLGLSLQSNRRILRGLLTPQDQDDQSTEKILQYIKQKFDANLSPERSINLFYCLNELNEQTLVKEIQTHLSKGSLSSADFSSAHWSALAFVLLTSDEEMEEFELQKFHKSDECLIRLSAVIKTCKRALLNDCNLTDRSCSALATVLESDTSLKELNMSNNNLQDSGVKLLCTGLKDMKCELEILRLSDCNITEEGYKALASALRSNPSHLLELDLRGNDPGESGVKELDDLLQDPNCTLKTLRFLSPSAEESCQFVNGVVGKNPLLLKTLNLNDFRSTRNHPFIYEIEDTQVNHLAALLQDKHCRVNMLILGGCSFTDDQWESLTSALKLNPSHLRELILMWNGPGESGVKILSDFLIEPQLKLEKLCLCYCSITEERCEILTSALKSNPSHLRELNLSQNIPGDSGMKNLSDLLMNPQSKLEKLQLCKCSITEEQCVILTSALKSNPSHLRDLNLSLNNLGDSGVKTLSDLLMKPHLKMEKLWLCKCSITEEQCVILASALKSNPSHLRELSLSENNLGDSGVKNLSDLLMKPQFKLEKLHLSHCSITEEQCEILTSALKSNPSHLRELDISKNQIRNTGVNLLCDVLNNSDCKLETLRLNDCGITDVSSLTQCLTNTKALQFLKVLYLRENHIGDSKQELSDVVRDSNCELSVDEFSLPDFGQIKDIKCCIS", "length": 1370 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCS9-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLQKKNEDEDEESASEMSYPPPESSCVSMKSDWSMVYPPDLSDASVTSDPNNSKRKGQHLEFKESSCVSVMSNRSITPPEMKKIGLKSEDNMLEKIKNKHKTSMKHKYERLFEGVKLHENQTLLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVGVSDASVYSGICTEIFKEESVIQQRKVYSFTHLSIQEFLAAFYVFYYHITCSTEACFDSLHDLQRRAVDKAIESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITSGLRKYACFLTLDPITAHTQLQLSEENRKASIVTDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGLVAVAYKGIGRKSGFDCCFGHNEHSWCLYCSDEVYSVWDNNKSVDVFGPSSRTNRVGVYVDVPSGCLSFYSVSDTNTLTHIHTFNTTFTEELYAGFKVYPGSSVSLCPVKPAEVPP", "length": 988 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUW9-1", "protein_name": "NLR family CARD domain-containing protein 3 isoform X1", "gene_name": "si:ch211-196h16.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKGNTGFRVKPPEPSGVSMKSDRSMHHPLKFKGGIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDPMFRPPEPSVSEKSGQSVDPTLKFSVHTCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDIGEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSINLFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQLDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLRLRCCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLCRCGVSDEGCAALVSVLSSNSSNLRELNLTENKVGDSGVKLLSAGLKENSKLEKLWLFICGVSDEGCAALASILRSNSSNLRELDLTGNKVGDSGVKLLSAGLKDPHCKLEKLTLDFCGVSDEGCAALASALRSNSSNLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC", "length": 1041 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32T552-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:ch73-50f9.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSGKHSVRSGSCVSRSVSLKSDESRKGLPPEFSEQPPSSNRSVEYELSDSVDKTHCNRKSFTDHLLRIFQDLESKIFKVLKNELERFRQILQGENTQDFVKGSNENQSSITKSALDLTLLFLREMKQDEVADTLENELLFINRLKSSLKKTYQSVSEGIAQQGDSTLLNNIYTDLYITQGANEQVNTEHEIRQIEAASRCHKSLEIQVECKHLFEAPEQDKQIRTVLTKGVAGIGKSVSVQKFVVDWAEGKANQDISLIFPLPFREMNLKEKEKQSLKDLITQLFPEVKGLNLTRRTRNKVLFILDGLDECRLPLNFAGNETCHDVSAPAYLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLADQNLAMEIIEHIKQSKSLHIMCHIPVFCWISATVLQNVLKETKVKHKACAKTLQESPKTLTQMYTHFLRFQMQQSRQKYDGKNTDGVSWDQNFILSLGKLAYQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKQETGIILGNLYCFLHLSIQEFIAALYGHLYLDIKKKSVFTGQKHKNKGMTHLLKTAVDKALESDNGHLDLYLRFLLGLSLQTNRQLLRGLLTQQDKSDQSKEEIVVYIKQKLEENLSPERAINLLYCLNELNDHSLMKEIQSHLRDGSLSSADLSPAQWSALTFVLLTSEEELDEFDLQKFKKSDECLIRLSAVIKSSKRALLQCCNLTAQSCESLSSALQSSNCVLRELELSNNDLQDSGVKLLSCGLRSLNCPLEILRLQCCNLTAQSCESLSLALQSSTCVLRELDLSNNDLQDSGVKLISNGLKSCKLEILRLSGCMVTETGCGFLSSALSSNPTHLRELDLSYNHPGVSGVKLLCQKLEDPNYTLAKLNVDHAGAKRITAGPRKWISHLTLDPNTANTELSLSAENREATRVIEKQPYPDHPDRFDYHPQVLCRESVCGPCYWEIDWSGDVGACISVSYKSVSSKGNDEFGCNDQSWSLSCYSSRFSYGHNNRWTDLPVKPISRRIGVYVDHRAETLRFYNICGNTVHLVHSVRTTFTQPLYAGFKIYPGSSVKLC", "length": 1099 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TA29-1", "protein_name": "NLR family CARD domain containing 9 isoform X3", "gene_name": "nlrc9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTKISKDEDYSPRFSSVHQERSDLEPSCVSMRSEQSMGSPMHFRSEDTEADLSSVYQKRSDPEPSCVSMRSDWSMDLPYNFRSEDTPTDLSSFHHKRTEAEFSRVSMRSDMFINHPINIKNVEAQCNIRQNLLNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFESAVRLCDISESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPMFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDEFEQIKKQSLWFKVKDLFQLNSLECVSLFSLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQRLMKLKSRSMQTNKTVKYIKMKIWTIDSPEKSINLFHCLNELGDHSLVKEIQQYLKSGRINRAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAGNNENKKQKVFQKLLPVIKQSRSVLLYNCGLTEMDWDNLTSALRSNPSDLRVLNLSRNILGNSVTLLSAVLEDPCSKLEKLWLSDCGLTDEGCAALATALRSNPEHLRELNLSWNNLRDSVTLLSAVLEDPRCKLETLWLSKCGITGKSCAVLASALRSNPEHLRDLDLSGNKLGDSVTLLSAVLEDPHCKLKILWLSDCGLTDEGCAALASALRSNPGQLRVLDLSENKLKNSGVMQLCAVLEDPHCKLDKLGLYDCSLTDEGCVALASALRSNPEHLRELDLSVNKLRDSGIKLLSAVLEDPRCKLEKLWLSNCGLTDEACAALASALRSNPEHLRELNLSKNKLGESDVKLLSDLKDDTHYKLKELNY", "length": 1079 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TJY6-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkeyp-100h4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQQIQETRLKGDTRASQTISSPSSSCSMAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKDCPPVFSGETPSSAQSVEFESADSGDETHRRHKSFTDNLQSIFQNLESKMFTFLKNELEKFKKILQENRQEIVKEFNENRSRITEAALDLTIFFLREMKQDQAADTLVGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVKCKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDDQKQEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGFVLHTMYCFLHLSIQEFIAALYQHLILDNDKTQAEKSRDESMIDLLKAAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEANLSPERSINLFYCLNELNDQSLLKQIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAIIKTSKRALLQGCYLTVPSCESLSSVLQSSNCVLRGLDLSNNDLQDSGVNLLSDGLKSQHCKLETLRLVMCNLTVESCESLSSVLQSSNFVLRELDLSNNDLQDSGVKLLSDGLKTVNCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVELLFEKLADPNYTLDKLNLDHGGHTRITAGPRKNACFLTLDPNTTYAFLILSEENREVKTVREYQLYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDDYVDISVSYKSIMRKGVDPECVFGRNAQSWSLCCDSSSFTFWHNDTDTRLPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLWPGFTVWCQSSVKLC", "length": 1125 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TMV3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like", "gene_name": "si:ch211-197e7.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDWSKEDPPKFSEKTPSSAQSVRSGSCVSSSVSLKSDRSKEHPLPNFREKTPSSAQSVEHELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNEMEKFKKILQEENRQEFVKDYNENRSRITEAALDLTLFFLREIKQDQAADTLQDELFSINQFQCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNNEHEIRQLEAASRRHQSLETQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNKTCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKILFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALENENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDESKKKIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFMLLTSEEELEEFELRKFQRSDECLIRLSAVIKTSKKALLQSCNVTVQSCKSLSKVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLAMCNLTVQCCESLSLALQSSNCVLRELDLSNNDLQDSGVKLLSNRLKSQYCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDKLNLDHGGEKRITAGLHKYVCFLTLDPNTAHIQLILSEENRKVKPVREDMMMMRKDQPYPDHPDRFDGLYPQVLCRESVCGCCYWETDWSGDGGVCISVSYKSIRRKGGVECEFGRNAQSWSLHCSSSRFIFIHNNTETRLPVKRLSKRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRVYSGSSVKLS", "length": 1140 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TPE7-1", "protein_name": "Protein NLRC3 isoform X4", "gene_name": "si:dkey-11n14.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKYSVRSGSSSSVSLKSDWSKDEPPKFSEKSPSSARSVEYELPYSGDKTHRSHKGFTKDLPRIFQNLESKIIRYLKNELEKFKKILQEENRQDFVKHFNENRSIITEAALDLTLFFLREMKQDEAADTLEGELFFINQLKCGLKKKYQNVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTTGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKENQSLKDLITQFFPQTKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTKLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISANVLLNILKENRNTELKHRDNSETLHESPKTLTQMYTHFLRFQIQHSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYDSDLKDCGIDVYKASVYSGMCTQIFWEETGIILGTMYCFLHLSIQEFIAALYQHLFLDSDKKHLSIFRQKSKNKVMTDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQNDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSADLSPAQWSAVAFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQGCNLNVRCCESLSSALQSSNCLLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDTLNLNHGGEKRITAGPRKYVCFFTLDPNTANTRLILSKKNREVKCVRENQSYPRHPDRFDDHPQVLCRESVCGRCYWEIDWSGGNEVCISVTYKSIRRKRGYECRFGYNAQSWSLICSSSRFSFTHNDTHTDLPVKPFSRRIGVFVDHCAGTLIFYNIYRDTMSLIHSVQTTFTEPLIPGFWVYSGSSVKLLKTEERFTQNPLQDQ", "length": 1060 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQ28-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:ch211-226o13.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTHTSGDLDLFTSCSVDGDDQTRDLQQDSLQPEHDELQRAKNQHKTSMKNKYERLFEGINHGETQKFLNRIYTQLYIIEGESEGVNREHDVLQIEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQGVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITARPAAAHQIPSTYIHRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDQEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFHCYLTDKREPVMLLYESKYSDDEDVSDGNEYEDSDVQFLQSSSEFSLCHLLSLAIYKAVMSSNGHLDLFLWFLLGVSLESNQRLFQDLLTHTEESSESIRIITQDIKDKIKTDDDLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSERELSPAHCSTISYMIEMSEEPLDELDFNKLNTSPVGRWRLIPAVRNCRRALLQWSYLSVQYCESLFSALKSSNCVLRELDLSTNDLQDSGVKLLSDGLKSPNCKLETLRLQCCNLTAQSCESLTSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCKLETLRLVMCNLTVQCCESLSLALQSSNCVLRELDLSNNGLQDSGVKLLSDGLKSQHCKLDTLRLVMCNLTVQSSESLSSALQSSNCVLRELDLSTNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGLHKYACFLTLDPNTTYAFLILSEENREVKRVREYQQYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDGCSVCTAVSYKSIRRKGRGAECLFGRNAQSWSLCCSSSSFIFRHNYTRTELPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFTVWCQSSVKLC", "length": 1145 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQA8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-29j8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEEQVKDSLSEKQSVRSGSCVSSSVSLKSDNSKGGRTPNFRGKTPSSVKRFFHLGKSKHPPSNLREKTPSSAESFQYELPDSRNKTHRSQKSFRGHLQKIFENLESKIIKFVKKELKNFRKILQNENRQEFVKEFNENSSGITEAALDLTLFFLREMKQDQAADTLQGELLYINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSVVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDTQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVLCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNKVMINLLKTAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQCCNLTVQCCESISSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQQCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGEKRITAGPHKYVCFLTLDPNTAHTRLILSEENREVKCVRENQPYPDHPHRFDYYLQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGAECAFGRNAQSWSLICSSSSFTFRHNNSHTDLTVKPLSRRIGVFVDHSAGTLIFYDIYRDTMSLIHSVQTTFTEPLCPGFYVSYGSSVKLS", "length": 1064 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TTK4-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAMNRLMTDMLEELVEAELKQFTRQLWMGVKPGVDPIPRGKLENKDRQDVVDCMVQHYSKDAGKIAVQALRSIKQNERADRLELNLRKDDDFLGEVLKKHKESIKASVDVFEGKKDNKTDINKVYTELFITEGDMTDVCKEHEVQKFDLALQMPRSEDKPIDCNEIFNLLRGKDKGNVVLTKGIAGIGKTFSVNKFILDWAEGRANLDVDCMFLLPFREINLMIKDGDVSLHKFLLKLFPDITGVETTPFYEKCKLLFIFDGLDESRLDLNFNLSSVDDVHSCASIDGLFTSLIKGRLLRSSLIWVTSRPAAANRIPSYHVGLFTEVRGFTDKQKEEYFRKKVPDEDQASRIISHIRTSRSLYIMCHIPVFCWIIATVLQDILQKNKGEDIPSTLTEMYIHFLLIQMNIKNQKYDEKLIRDRTELLGSNRDMISKLAKLAFEQLKKENVMFYREDLAACGINADEEFTGLCTEIFKKDSVLHELKVYYFIHLSVQEFLAALHVFLCYLELEKDMNLTDSDLMFFLEDSRPKQKELLHVLLRKAIDKAEKSDRGHFDLFLRFLLGISLESNQKLLIGILNETKNSKQSISKTVQYLKQLQNNDKCPDKSINHFFCILELQDRTLYQQIMKYLRSKTNRPKVMSRSNCSALVYVLLMSQEVLDKFNPKLFNKTYAGCRILVPAVRCSRKALFSDCGLTETCFETVALALQLENCPLVELDLSYNYSLEAAVNVMCAGLKSPHCHLESLRLAGCHLGQDSCMQVVSALQSISHRLKELDLSGNDLQDSGLQKLLQGMENTEKRLQVLRLSWCNLTEMSCQQLSTILSSNSVFRELDLSNNDLQDSGVKLLSDGLKSPNCKLKILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHCKLKTLKTDPMGDHLMKPGIVKYAFNLTLNPNTAHVHLLLSDGDRKVTLKEKQPYPDDPERFEEHHQVLSRESLSGRCYWETEWTGQEGTVGVAYESIPRKPDDLLYGRCMLGNNIISWKITCGSRTHVSHAEEDITVKSPSSGSCKRVGVYVDTTAGVLSFYHVFDTLTHLYTFLMPFTQPLYAAFRVDGESVSICPIP", "length": 1114 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TUF4-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch73-236c18.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHHCGNEEVDREEKEKHGAEHSCVSMKSDQSMRNPIAFTDKAVTFDLRSVASSSSHFETHTVQEKTDKGLQTQIFETEELQRVKDQHKTSMRKKYELLSEGIKVKETGTQLNRIYTQLYIIEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFYVFYYHVNTTMMGLKTFASLQKLLKGAVDDAIESKNGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCRLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRIKPGLKKYACFLTLDPNTAHVQIQLSEGNREARNVKDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYCCDTNYTVWYNNESADIIAPSARTNRVGVYLDVSSGSLSFYTVSDANTLTLIHTFNTTFTEPLYTGFGLYPESSVSLCQI", "length": 969 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HUA8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 1 homolog isoform X1", "gene_name": "LOC103910107", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDQDSERAQFVDAHWKTLVQRVIMVMAIADELQSDGMLEWEPYCKIKAAVTNQQKMRELYEVLQSGGDQVKSAFYSSLEKHEPYLLGDLGSIKLMGESLADCLNKYKMWIQKEYEYVTEYNSLPGENVLLSERFTQPLIIMRHRERREREEEMCSVGESFQQLLVSRNNADKDSSILDALFGADSKGISPNSVILQGNSGNGKSFTAQKIMLDWASGKLCKVEFDCLFHLKCKEVNHVSGEQSLTELLSYNSNLTSEQISRILQKSSEKVLILIDGFDELRFSFSDFSDHLKLKDLSEKAPREASLKVLLMGHILSKTSLLVTTRSTATNTLDSLLKHPKRFTEIMGFSEREVKEYFQKFFQDEELFIKAYEYVRSNETLITACSIPVICWIICTVLRERFSEGSDLTSGLETTTSIYVDFVCTLLEHHSQGLSQPVPTLLRSLGQLAERGMLDTQVLFEEKSVDEMVSASPFLCKFLFKRRIRKETMFSFMHLSFQEFFTALYYISQEEREFLDKLTERFHSQTQSYLSLYLDKDFPLKYGCPEPHFLPVVQFLCGLSNSEVSRSLQEMYNLSVPSFVQPQLREWILDMSKSGVYSYLPFILHCLYELHEKEFVQKAMEAWLELDMSWDPLSRTDCWALLYCLDCCPHFRSLKLNFAASELKMLQDVLCRTPKLGLTVQNVSDTDVTVLLSALGEGKQLGELKLNSSCLSDQSVQQVLKALHKQKKVGGLQISVKSITADTALILTDFLQSCSKAEWEEISGSLSTSDVESLCSSLRLFSFEGKLVVNVVRLCLSIQNQPSLSEIILNCPRSEASNIDIKSFTESFHNINCIAEESVDFDRNLHALLTLLTSMSGLSALNLSVPFLTETWASRVLFLVESSPKLTVINFHAGSWCSDGVKWLPGLLLEEGIKLLKESAKRPECIVNIRGFRCSKSSERCSRHTEHIDQLSCNQRVTIQFCGDQCTEDIKLKLVLPDEN", "length": 979 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HZJ9-1", "protein_name": "Uncharacterized protein si:ch211-149a19.3 isoform X1", "gene_name": "si:ch211-149a19.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDKEASNDGDFSSRRSHFQSQKSNTSESNPEITPEDLSAKKLIKMFEKRTPDNQSKFNNQKSNTAKSIRSDRSIQNPVKIKEIRTPADLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPKPMPRSIKSDQSTPELDKVDGGHTSTALSSQRSNPPDPKPRSIKSDQSTPEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGIGCQRSNPPDPKPRSIKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPESSLVSLKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSMPEPIKFDGGHTPTGLSETSTNDQFMNKQVKIKRRHTLTGLSKTSINYQFMEKQLKTERRHTSTGLSLNSKLFENLLKSNLLKKFQCVSEGTSILGNPTLLNEIYTELYITESDSGEINNEHELRQIETQSRRSAKEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEKNKNQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEHYKVLFIFDGLDECRVSLDFDSGVKLHDVSESASVDVLLMNLIMGNLLPSALIWITSRPAAADLIPSGFVHRVTEVRGFNDPQKEEYFRKRIRDQSLADTIISHLKSSRSLHIMCHIPVFCWISATVLEKIFSQAERGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEDKDMILKLGKLAFEQLQKGNLIFYEEDLRECGLDLTEAAVYSGLCTQIFREEFGFSQSKVFCFVHLSIQEHLAALYAHHFLTNNCLNKHWKTFNPLSFLHQRAVNEALQSKNGHLDLFLRFLLGLSLEFNQTLLQELLTQTGSCSYNTEETVQFIKQKIREINSPERSINLFHCLNELGDQSLMKEIQNYLRSGEIKETKLSSSQWSALVYVLLTSEQEMEDFDLNQFIGTQNTADEVLQKLQPVVKESRSVQLSGCSVTDKGCAALALVLRSDSSHLRELDLSENNLRDSGVKLLSDGLKDPHCKLEKLRLSDCGVTDEGCAALASALRSNSTHLTELDLSLNNLEDSGVKLLSDGLKDPHCKLEILRLSDCGVTVEGCADLASALRSNSTHLRELDLTLNNLEDSGVNLLSAGLKDPHCKLEKLRLSDCGFTDEGCADLASALRSNSTHLTELDLSLNNFGDSGVKLLSDGLKDPHCKLEKLRLSYCRVRAEGGVALASALRSNPEHLRELDLSENKLGNSGVKMLSELKNDSRYKLDTLKF", "length": 1375 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCJ8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12-like isoform X1", "gene_name": "si:dkeyp-77c4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKEEHLPNFREKTPPSAQSVRSGSCVSSSVSLKSDWSKRDPPNFREKTPSSAKSSVHQKRAEAEPSCVSMKSDWSMNRPITFRSKITQPAISVDRDDQTGHLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSAQKFILDWAEEKDHQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCALTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQIHMRKQKYEERDPEKLLQSNRGVILKLAEVAFSQLMKGNVMFHEEDLTESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVLYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESTESIRRITQHIKDKIKRDKRLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDELDFNKLNTSAEGRRRLTAAVRNCRRALLQGCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLQWCKPTVQSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLVMCNLTVQCCESLSSALQSSNYVLRELDLSNNDLQDSGVKKLSDGLKSPNCKLETLRLVMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKRNCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKWVCFLTLDPNTAHTQLILSEENREVKRVRENQPYPYHPDRFDVHRQVLCRESVCGRCYWEIDWSGDVGVCISVSYKSIRRKGRGVECWFGYNAQSWSLICSSSRFSFRHNHTDTDLPVEPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFTVYSGSSVKLS", "length": 1235 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCK2-1", "protein_name": "Uncharacterized protein si:dkey-26m3.3 isoform X1", "gene_name": "si:dkey-26m3.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGYVFVLSSLCPVFILLQFLLEFLLEIKLFRSIMGNTHAAGDQDLSTECSSVHQKRAEAEPSCVSMKSDASMGVPITFKSENTGPAVSSVHQKRAEAELSCVSMKSDASMNPPIEFKSGNTGPAVSVDRDGQTGDLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEQIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKDNQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPKLEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTEPSSVAVLMRSLLKGDLLPSALIWITSRPAAAHQIPSTYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLDSNQRLFQDLLTHTEESSENIRRITQYIKDEIKRGKHLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELTPAHCSTISYMIEMSEEPLDELDSNKFNTSDVGRRRLIAAVRNCRRALLQRCELTVQCCESLSSALQSSNCVLRELDLSNNDLQDSAVKLLSDGLKSQHCKLETLRLMTCKLTADSCESLSSALQSSNCVLRELDLSNNDLPDSGVKLLSDGLKSQHCKLETLRLQWCKLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLAMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKTVDCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKYVCFLTLDPNTANTRLILSEENREVKHVRENQPYPDHPDRFDGVYQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGVECWFGSNAQSWSLSCSSSNFSFRHNNTRTDLPVKALNRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRIYPGSSVKLS", "length": 1239 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCL0-1", "protein_name": "Uncharacterized protein si:dkey-165o8.1 isoform X1", "gene_name": "si:dkey-165o8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDQSKDHPPYFREETPSSAESVEYESADPGDETHRRHKSFTDNLQSIFQNLESKIIRFLKNELEKFKKILQEENRKEFIKEFIENRSIITEAALDLTLFFLREMKQDQAADTLQDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNKIYTDLYITQGASEQLNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCGDVSSAVSLDVLLTNLIMGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILRLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLDRNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLDIDKKRGWFLIQISKNKSMIDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQFCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKCRTTHTQTHTHTHTHIHTHTHTHTHIHTHTHTHTHTHTRAHTHTHTRGLQQDRANVGPHTYTHTHTHTHTYTYTHTHTHTHTHTHTHTRITAGPRKCRTTHTHTHTYTHTHTHTITHTHLHIHTHTCTHTHTCAHTHTHIHTHTLTHTRTYTHTHTHTLPLTHTHTHTLSHTHTHTHTNIHTHSLTHTNIHTHSLTHTNKHTHSLSHAYTHACMHALSHLHTHTHALTHTHTHTHTHSLTHTHICTHKHTHTLSHSHKHSHTHTHTHTHTHTHTQARAHLHKHTLSHTHTHIHIYTHTYKHTHILSHTHAHTHTHTQARALTQTYSLTHTHTHTHKHTLSHTHTHIHHTHTQIHIHSHKTHTHARTHTLSLSLTHTHTHTHTHTHTHTHTHTHTHTQLWL", "length": 1266 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JD10-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch211-203c5.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVGYDTECSVCVVCSRMLVCVCVVHLRCSMAEERVKDSLSEKHSVRSGSCVSSSVSLKSDWSKGNPPQFSGESPSSAQSVEYESADSGDETHRRHKSFTDNLQSIFQNLESKMIRFLKNQLEKFKKILQEENRQEFVKEFNENRSIMTEAALDLTLFFLREIKQDQAADTLQDELLYINQLKCSLKKKYQRVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCHDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESSKTLTQMYTHFLRFQIQQSRKKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDRDKKHGLFLQIGKNKGVTDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKKKIIAYIKQKLKGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGRLSSARLSPAQWSALVFVLLTSEEELEEFELHKFQRSDECLIRLSAVIKTSKRALLQSCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPHKYVCFLTLDPNTAHTRLILSEENREVKRVRENQPYPDHPDRFDGYVYPQVLCRESVCGRCYWEIDWSGDDGVFISVSYKSIRRKGGGVECWFGCNAQSWSLLCDSSSFSFRHNNTLTDLPVEALSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCAGFGFSSGSSVKLS", "length": 1073 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z7N0-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Dmel\\CG8197", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCDVLLPCEYNPKECPSPAAEKSRLFTILLLYCWQREYDKRPYRQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLRRPQLSVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPREFFVMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANRLLGMSLSLDTEKISSVLSSLLMQNTLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLAMKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISYTYDEALQDYRVVPWR", "length": 387 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZAD9-1", "protein_name": "NLR family, pyrin domain containing 9", "gene_name": "Nlrp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDTSGYGLLKHLRKLSDGEFWSFKELLRKEPEKFKLKPISWMKIENASKEELVMLLNTHYPKQAWDMALSLFLQVNREDLSIMAQKKRRYKQTKYKKFMKTTFQSIWTLESNICIPDRSYHLIVEHQYRKLQNIFDSESEPVTAVVTGPTGEGKTVFLRKAMLDWASGILWQNRFQYVFFFSVLSLNNTTELSLAELISSKLPESSETLNDILSDPKKILFILDGFDYLKFDLELRTNLCNDWRKILPTQIILSSLLQKIMLPESSLLLELGHISLPKIFPLLQYPRDITIQGFSERCLKTYFISFFNTEKGIEVFENLKSNQMLKLCSNPYLCWMFCSCLKWQFDREEEAYFQAKTDSVFFTSFMVSAFKSAYASNPPKQNRAQLKSLCTLAVEGMWKQLFVFDSEDLRRNGISESDKAVWLRMKFLQNHDNHIVFYHPTLQLYFASMFYFLKQDKDTHVPVIGSIPQLLRKIYARDHTQWLQIGIFLFGLATEQVASLLKPYFGFIQHRDVRQEVMRYLKSLSQRECCEKLERPQNLFACLRDNKEEKFVREVVDLFEEITVDITNSHVLSIIANHLQKSSKLKKLHLHIQKRVFLEIHDPEYSDSETFTQDKKNAAEYWKKLCHIFVNLHVLDLDSCNFNKQVIEELCNVLSPSPKIPLMAFKLESLLCSFMTNFGDGSLFHTLLQLPHLKYLNLYGTNLSNSRIENLCSALRRSTCKVEELLHSEMSFPLSTDFIVSHKFGLGKCDISSEACGIIATSLMNSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLETLMLSYCCLTFIACGHLYEALVSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCILKELWLSGCFLTSECCEEISAVLTCNNNLKTLKLGNNDIEDTGVKHLCEALSHPNCKLECLGLDLCKFTSDCCEDLASALTTCKTLNSLNLDWKTLEHSGVVALCEALNHKKCNLKMLGLDKSAFSVESQTLLQAVEKKNNNLSILHYPWVEEERKKRGVRLVWNSKN", "length": 1022 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZP31-1", "protein_name": "NLR family, pyrin domain containing 4", "gene_name": "Nlrp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEILQLRLKQISWTKVKKASREDLANLLLKHYEEKQAWDMTFKIFQKMNRKDLIERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKAQDLFKQKFTQDDCDRFENLLVSKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGIVFQNKFSYIFYFCCQDVKQLKRASLAELISREWPNASAPTAEILSQPEKLLFIIDSLEVMECNMSERESELCDNCTEKQPVSLLLSSLLRRKMLPESSFLISATPETFEKMEDRIECTNVKIITGFNENNIKMYFRSLFQDKNRTLEAFSLVRENEQLFNVCQVPVLCWMVATCIKKEIEKGRDPVFICRRTTSLYTTHIFNLFTPQNAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFSEEALRRNGILDSDIPTLLDRRILERSKESESCYIFLHPSLQEVCAAVFYLLKSHLDHPSQDVKSVEALLFTFLKKAKVQWIFLGCFLFGLLHESEQEKLEMFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEAFLMQAMNCMEQINFVAKDYSDVIVAAYCLKHCSTLKKLSFSTQNILSEEQEHSYTEKLLICWHHMCSVLISSKDIHVLQVKDTNLNETAFWVLYNHLKYPSCTLKVLVVNNVTFLCDNHLFFELIQNQRLQHLNLSLTFLSHSDVKLLCDVLNQAECNIEKLMIAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLCKALCHPDCILKHLVLANCSLSEQCWDYLSEVVRRNKTLSHLDISSNDLKDEGLKVLCGALTLPDSGLISLSVRHCLITTSGCQDLAEVLRHNQNLRSLQVSNNKIEDAGVKLLCDAIKQPNCHLENIGLEACELTGACCKDLASAFVHCKTLWGINLLENALDHSGLVVLFEALKQQKCTLHVLGLRITDFDKETQEFLIAEEEKNPYLSILSNV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZUH1-1", "protein_name": "NLR family, pyrin domain containing 4A", "gene_name": "Nlrp4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLGLKQVSWTEVKKASREDLASLLLKHYEEKQAWDMTFNFFQKINRKDLIKRAKREIDGYPKLYRAHLKTKLTHDSSRIFNINIQDFLKEKFTKDDHDRFETLLQSKGTESKPQVVVLSGVAGIGKTLMLKRLMLAWIEGLVFPYKFSYIFYFCCQEVKQLKTASLAELISREWPDPSAPIEEILSEPEKLLFIIDSLEGIECDLFKCDSELCDNCMEKQPVNILLSSLLRKKMLLEASLLISTTPETFEKMEDRIEYTHVKIITGLNESDIKMCFHRLFQDRNRAQEAFSLVRENEQMLTICQVPVLCWMVATCLKTEIEKGRNLVSTCRRTTSLYTTYIFNLFIPQSAHSPSKKSQDQLQGLCSLAAEGIWTDTFVFTEEALRRNGILDSDIPTLLDIGMLGKMGKFENCYIFLHPSLQEACAAIFYLLKSHGDHPIEDVKSVEALLFTFLKKAKVQWILGGRFIFGLLHESEQKKLEAFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEDFLMEAMNYMEQINFVAKDYSDVIVAAYCLKHCYTLKKLSFSTQNILNEEHEHSCMENLLTCWRHICSVLINSKDIQELQIKDTNLNEPAFSVLYNSLKYCNDTLKVLVENNVFFLCEKYLFFELIQNCNLQHLNLNLTFLSHSDVKLLCDVLNQAECNIEKLEVAACNLSPDDCKMFASILMSSKTLKQLNLSSNILGKGISSLCKSLCHPDCILEHLVLAKCSLSDQCWDYLSDGIRQNKTLNHLDISSNDLKDEGLKVLCRALALPNSVLKSLCLRHCLITTSGCQDLAEVLRNNQNLTSLQISYNKIEDAGVKLLCDAIKQPNCHLEDLGLEACELTGACCEDLASTFTQCRTLWGINLLNNTLDYTGLVVLCEALRQQKCTPHVLGLRITDFDNETQAFLVAEQEKNPDLSILSGV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A1P8-1", "protein_name": "NLR family, pyrin domain containing 4B", "gene_name": "Nlrp4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLFSDFGFMWYWKELNKVEFMKFKELLILEILQMGLKQISWTEVKNASREDLAILLVKYCEGKQAWDTTFKVLQKISRHDLTERATGEIAAHANIYRAHLKKKLTRDCSRKFSISIQNFFQDEYDHLENLLIPKVTEEKPQLVFLKGIAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCQDVKQLKTTSLTELISREWPSSSAPIEEILSQPEKLLFIIDSLEGMEWDFTKQESELCDNCLEKQPVNVLLSSLLKKKILPESSLLISATFETFEELKDWIEYTNVRTITGFKESNIKMYFHSLFQDRNRALEAFSFVRENEQLFTLCQAPVICCMVATCLKNEIEKGKDPVSICRRTTSLYTTHIFNLFIPPNVQYPSKKSQDQLQGLCFLAVEGMWTDISVFSEETLRRNGILDSDIPTLLDIGILEQSRESQNSYIFFHPSVQEFCAAMFYLLQTHMNHPSPDVLHVEKLLFSFLKEVNTQWIFLGRFIFGLLNELEHEKLEAFFGYQLSQQLKQELFEWLELLLDPEVKVNTMKFFYCLFEMEEEVFVQSAMNCREEIDVVAKDYYDFIVAAYCLNHGSALRDLSISTQNVLNEKLNQRYMENLLMLWHNICSVFARNKDIHILQMKDTIFNEPVFQILYNYLKNSSCILEVLVANDVSFLCDKYLFFDLIQSYNLELLDLSGTFLSHSDVVILCNILNKAEYKIQELELANCSLSEQSWKYISDVLCQNKTLRHLDISSNDLKDEGLKVLCKALTLPDSVLLTLSVKACFITTVGCQYLAEVLRNNHKLMFLTLSENKLEDSGVKLLCDAIKHPRCQLAQLDLEACELTGACCEDLASTFTQCKTLGWINLVKNALDFNGLVVLCKALKQKTSNLKELRLRITDFDNKSQTFLLSEEKGNKFLNIENDE", "length": 918 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A523-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWNDACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGRTKMWDRPMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEEEEKRGSQPLDQVQCVFPDPHVACSSRLVNCCLTSSFCRGLFSSLSTNQSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSSQKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTNQNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNCETKRTLEALQEEKPELTVVFEISW", "length": 1035 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FA88-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "nlrc11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYCNYNMDNTRSSRDEDIYSCTSRESEEVLSNTSYWSLPSYFRHRKFHRSSVHEKISDSSESSRVSLKSDWSMNPPPLLGEERKSSNLNMSSLVSVRSDWSMDPPPLLRAKGKSAVSSGVSDNIDWLVCSPYLRVERKSSALRHKLSLLKKFQCLYEGTAVQGKPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLIKDKKFSLVSLLQTFFTREIHLDMIQNSAVIFIFDGLDECRLPFNFSRNEILLDVTKETSVDVLLTNLIVGNLLPYALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILRLGKLAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLLFTNHNINVFEQMTKSFEGTPLNKSDLQSLTLNMELFEISEPVLTDVAAMCEMDWRVVNEISALHCKAVDEVLQNKNGHLDLFLRFLLGLSVECNQILLQRLTKQRRHLYNDNKTVEYIKKKIRTINSPEKSISLFHCLNELGDHSLVEEIQQYLTSGKIKEFKLSSSQWSAVAFVLLTSEKKLEEFWLKEFVGAETKADHVLQKLLPVVKESRKAELSKCGLTEECCAALASALRSKLSHVRELDLSGNKLGDSGIENLSTGLENLHCKLEILRLRSCGITAKGCTALASALRSNPEQIRQLDLSENNIRDWGVKHLFTELKNPDCKLEILGLRNCGITIEGCAALTSALIINPSHLRELDISRNSLGDTGQELLTSLLNSQHHKLEILLLHKFPMTFTSLPSSHSPEMFPQRFRTHNLKE", "length": 966 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q5R7-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSTARDGLYRLSTYLEELEAGELKKFKLFLGIAEDLSQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGEDLVRVTPNNGLCLFESQSACPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPEPPHTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGPWCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTPRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFAAMYCALNGREAVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWSISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQVVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGSAYSTGMEDDPPEPSGVQTQSTYLQERNMLPDVYSAYLSAAVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISGSACQDLAAAVIANRNLIRLDLSDNSIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLSNNSYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVNTCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGISQTLHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFGMDLNKKTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M918-1", "protein_name": "NLR family, pyrin domain containing 14", "gene_name": "Nlrp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTEDEEMEDQLSKEEIVSEDKEFDYRTIIKENFFIIWDKTSLLGESATLNCVTTHKDQKLLEHIFDVNIQTSKSPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLSGREISQEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFALCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMTCQTSTALFTYYICSLFPRIAGSSVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQDTECENCYTFTHLQVQEYFAALFYLLRENPEEKDHPLEPFENVHLLLESNHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLTISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVKVDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDPTAEICLEDAAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLNSCYDFSFLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQSNRSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTKTKRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNNKSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNNSNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNNQSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCPNTESGCWWQYF", "length": 990 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RA38-1", "protein_name": "NLR family pyrin domain containing 2", "gene_name": "Nlrp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHSDQLGFNLKDVLKKLDKTELNNFKSTLKSCSLPQTMKQISKLTMDLANGAQLAEILTDYCPNDWVKRVTFKILEEINRADLAELVMKQVEEAASKASEEKVSSKPREPLKTSLFPQDFVQGDERPEHKHKKEWRNMYTEKWKKNFWPKCNKEIYVDTESYRTLLTLCNPKIEMPFAYTIVLHGPPGSGKTTMARRLMLEWSESKQAQSFSCAFYISCRKLNNSKPCTFAHLLSMNNPSWRYYMIRRLVLSEQFLFVVDGFDELTFPAGALLRDICGDWNTVKPVEVLLSSLLMRKMEPHSTLLVTTQTQSLHQIYLMVDQPVLVETQGFLEPEKQEYFQQYFEDEEGEEEGEGEGKALRALKEVKCNEALFQMASLPAACGIFCLCLELGMKKGEDLALTCQTYTSMFLNFLCRVFLQEACDGHLNKQLQILFKKICILAADSLLEQVPILCEEDFLKLKLNLNKLHPVVYRCIFLEDSSCTNCLSFICLSIQQLLAAIIFVQELGQESKDVSKYSIQKMLSREARLKNPNLSGVLPFVFSLLNKTHIQELETIFGCQISMGVKRKFLECELGENKPFLLLMDLQEIFSCLYESQEEEFVKEAMALFGEVSLHLKTNMDLVHASFCLKNSQNLQTMFLKVEKAVFPENFATLESTAEDQRFQDKKCMLTLWTDFCDTFHSNEKLAFLEIHESFLNSSSLEILCEKLSSAPCHLQKVVLKNISPDDAYEKLCLIFCGYETISHLTLQGGKLDSMLHSLCKVVKNPACNLKFLSLGSCSTTAQKWDDFFPALKANQSLISLDLTDNNLLDKGVRLLCNTWKQSKCILQRVSLENCHLTEVCCKDLSSVLMVSQTLTHLSLAKNELGDNGVKKLCESLSFPKCKLQTLVLWSCNITSNGCHYLSKMLGQAPSLKHLDLGLNRIGTTGAKFLCEALKSPRSNLKSLWLCGCSIIPTNCKDFSEILRSNKSLNTLDLSQNVMGTDAVKIFCESLKLQICPLQTLRLKFDEANPSIQKLIQEMKESHPQLSITSDQVDPKKKSHSFPHFIF", "length": 1048 }, "evidence": [ { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13489-1", "protein_name": "Ribonuclease inhibitor", "gene_name": "RNH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEARCKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGAGCGVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRDLCGIVASKASLRELALGSNKLGDVGMAELCPGLLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEGARLLCETLLEPGCQLESLWVKSCSFTAACCSHFSSVLAQNRFLLELQISNNRLEDAGVRELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAATLLANHSLRELDLSNNCLGDAGILQLVESVRQPGCLLEQLVLYDIYWSEEMEDRLQALEKDKPSLRVIS", "length": 461 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59044-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 6", "gene_name": "NLRP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGPDGRSIPWGRLERADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSEYKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQPQRLLFILDGADELPALGGPEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRLQGRLCSPQCAEVRGFSDKDKKKYFYKYFRDERRAERAYRFVKENETLFALCFVPFVCWIVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAREGVLGRRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAALSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLVLTTRFLFGLLSAERMRDIERHFGCMVSERVKQEALRWVQGQGQGCPGVAPEVTEGAKGLEDTEEPEEEEEGEEPNYPLELLYCLYETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLISCRLVAAQEKKKKSLGKRLQASLGGGSSSQGTTKQLPASLLHPLFQAMTDPLCHLSSLTLSHCKLPDAVCRDLSEALRAAPALTELGLLHNRLSEAGLRMLSEGLAWPQCRVQTVRVQLPDPQRGLQYLVGMLRQSPALTTLDLSGCQLPAPMVTYLCAVLQHQGCGLQTLSLASVELSEQSLQELQAVKRAKPDLVITHPALDGHPQPPKELISTF", "length": 892 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59045-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 11", "gene_name": "NLRP11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESDSTDFDLLWYLENLSDKEFQSFKKYLARKILDFKLPQFPLIQMTKEELANVLPISYEGQYIWNMLFSIFSMMRKEDLCRKIIGRRNRNQEACKAVMRRKFMLQWESHTFGKFHYKFFRDVSSDVFYILQLAYDSTSYYSANNLNVFLMGERASGKTIVINLAVLRWIKGEMWQNMISYVVHLTAHEINQMTNSSLAELIAKDWPDGQAPIADILSDPKKLLFILEDLDNIRFELNVNESALCSNSTQKVPIPVLLVSLLKRKMAPGCWFLISSRPTRGNNVKTFLKEVDCCTTLQLSNGKREIYFNSFFKDRQRASAALQLVHEDEILVGLCRVAILCWITCTVLKRQMDKGRDFQLCCQTPTDLHAHFLADALTSEAGLTANQYHLGLLKRLCLLAAGGLFLSTLNFSGEDLRCVGFTEADVSVLQAANILLPSNTHKDRYKFIHLNVQEFCTAIAFLMAVPNYLIPSGSREYKEKREQYSDFNQVFTFIFGLLNANRRKILETSFGYQLPMVDSFKWYSVGYMKHLDRDPEKLTHHMPLFYCLYENREEEFVKTIVDALMEVTVYLQSDKDMMVSLYCLDYCCHLRTLKLSVQRIFQNKEPLIRPTASQMKSLVYWREICSLFYTMESLRELHIFDNDLNGISERILSKALEHSSCKLRTLKLSYVSTASGFEDLLKALARNRSLTYLSINCTSISLNMFSLLHDILHEPTCQISHLSLMKCDLRASECEEIASLLISGGSLRKLTLSSNPLRSDGMNILCDALLHPNCTLISLVLVFCCLTENCCSALGRVLLFSPTLRQLDLCVNRLKNYGVLHVTFPLLFPTCQLEELHLSGCFFSSDICQYIAIVIATNEKLRSLEIGSNKIEDAGMQLLCGGLRHPNCMLVNIGLEECMLTSACCRSLASVLTTNKTLERLNLLQNHLGNDGVAKLLESLISPDCVLKVVGLPLTGLNTQTQQLLMTVKERKPSLIFLSETWSLKEGREIGVTPASQPGSIIPNSNLDYMFFKFPRMSAAMRTSNTASRQPL", "length": 1033 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59046-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "NLRP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQSTCLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELKPSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEGEGGAGPDQDVTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSAGAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIANKNLTRMDLSGNGVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC", "length": 1061 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 5", "gene_name": "NLRP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVAGGLELGAAALLSASPRALVTLSTGPTCSILPKNPLFPQNLSSQPCIKMEGDKSLTFSSYGLQWCLYELDKEEFQTFKELLKKKSSESTTCSIPQFEIENANVECLALLLHEYYGASLAWATSISIFENMNLRTLSEKARDDMKRHSPEDPEATMTDQGPSKEKVPGISQAVQQDSATAAETKEQEISQAMEQEGATAAETEEQEISQAMEQEGATAAETEEQGHGGDTWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDSDRWGFRPRTVVLHGKSGIGKSALARRIVLCWAQGGLYQGMFSYVFFLPVREMQRKKESSVTEFISREWPDSQAPVTEIMSRPERLLFIIDGFDDLGSVLNNDTKLCKDWAEKQPPFTLIRSLLRKVLLPESFLIVTVRDVGTEKLKSEVVSPRYLLVRGISGEQRIHLLLERGIGEHQKTQGLRAIMNNRELLDQCQVPAVGSLICVALQLQDVVGESVAPFNQTLTGLHAAFVFHQLTPRGVVRRCLNLEERVVLKRFCRMAVEGVWNRKSVFDGDDLMVQGLGESELRALFHMNILLPDSHCEEYYTFFHLSLQDFCAALYYVLEGLEIEPALCPLYVEKTKRSMELKQAGFHIHSLWMKRFLFGLVSEDVRRPLEVLLGCPVPLGVKQKLLHWVSLLGQQPNATTPGDTLDAFHCLFETQDKEFVRLALNSFQEVWLPINQNLDLIASSFCLQHCPYLRKIRVDVKGIFPRDESAEACPVVPLWMRDKTLIEEQWEDFCSMLGTHPHLRQLDLGSSILTERAMKTLCAKLRHPTCKIQTLMFRNAQITPGVQHLWRIVMANRNLRSLNLGGTHLKEEDVRMACEALKHPKCLLESLRLDCCGLTHACYLKISQILTTSPSLKSLSLAGNKVTDQGVMPLSDALRVSQCALQKLILEDCGITATGCQSLASALVSNRSLTHLCLSNNSLGNEGVNLLCRSMRLPHCSLQRLMLNQCHLDTAGCGFLALALMGNSWLTHLSLSMNPVEDNGVKLLCEVMREPSCHLQDLELVKCHLTAACCESLSCVISRSRHLKSLDLTDNALGDGGVAALCEGLKQKNSVLARLGLKACGLTSDCCEALSLALSCNRHLTSLNLVQNNFSPKGMMKLCSAFACPTSNLQIIGLWKWQYPVQIRKLLEEVQLLKPRVVIDGSWHSFDEDDRYWWKN", "length": 1200 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TKR3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4C", "gene_name": "Nlrp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLRLKQISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRKDLMERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKVQDFSKQKFTQDDYDRFENFLISKVTAKKPHMVFLQGAAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPKTSAPIEDILSQPEKLLFVIDNLEVMECDMSERESELCDTCTEKQPVRILLSSLLRRKMLPKSSFLISATPETFEKMEGRVECTNVKIVTGFNESNIKMYFRSLFQDKTKTQEIFSLVKENQQLFTVCQVPVLCWMVATCLKKEIEKGRDLVSVCRRTTSLYTTHIFNLFIPQSAQYPSKESQAQLQSLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPTLLDVRILEKSKKSEKSYIFLHPSIQEVCAAIFYLLKSHMDHPSQDVKSIEALIFTFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQVDGMKLFYCLFEMDDEAFLAQAMNCMEQINFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNVLSEGQEHSYTEKLLMCWHHMCSVLISSKDIYILQVKNTNLNETASLVLYSHLMYPSCTLKALVVNNVTFLCDNRLFFELIQNQCLQHLDLNLTFLSHGDVKLLCDVLSQEECNIEKLMVAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLVNCSLSEQCWDYLSEVLRRNKTLNHLDISSNDLKDEGLKVLCGALSLPDSVLKSLSVRYCLITTSGCQDLAEVLRKNQNLRNLQVSNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASAFTHCKTLWGINLQENALDHSGLIVLFEALKQQQCTLHVLGLRITDFDKETQELLMAEEEKNPHLSILSSV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X03-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9A", "gene_name": "Nlrp9a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDSSGYGLLQYLQKLSDEEFQRFKEHLRKEPEKFKLKPISWTKIKNTSKEDLVMQLYTHYPGKAWDMVLSLFLQVNREDLSTMAQTERRDKQTKYKEFMKNTFQHIWTMETNTYIPDRSYHEFIEVQYRALQDIFDCESEPVTVVVSGSRGGGKTTFLRKAMLDWASRNLLQNRFQYVFHFSVFSLNNITELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKKLPIQIVLSSLLQKIMLPECSLLLELGNASLSNIIPLLQYPREIIMSGFSEQTIEIYCVSFFNTQTGVEIFKNLKSIKPLFNLCRCPHLCWMICSTIKWQYERREVASRFGRTLGLLYTIFMVSAFKSTYARNPSKQNRARIRTLCTLAVEGMWKQVYVFDSDDLRRNGISESDKKVWLRMKFLQNQGSNIVFYHSTLQWYFAVLFYFLQYKDTRHPVIGNLAQLLGEIYAHKQNQWFHTRILLFGMATEQVNSLLEPCFGCISSKEVRQEIIRYIKSLSQQECNEKLVVHPQNLFFCILDNQEERFVRQLMDRFEEMTVDISDVDDMSATPYCLHRAPKVKNLHLHIQKRVFLEIHDPEYGDLELFKLGQKCSFTTNFGDGLLFCTFLHLPHLKYMNLYGTNLSNDAVERLCSALKFSTCGVEELLLGKCDISSEACGIIAASLINSEVKHLSLVENPLKNKGVMSLCEMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNEHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCYLTSECCEEISAVLTCNTNLKTLKLGNNNIQDTGVKRLCEALCHPNCEMQCLGLDMCDFTSDCCEDLALVLTTCNTLKSLNLDWNAFDHSGLEMLCKALNHKACNLEVLGLDKSLFSEESQTLLQAVEKKNKNLKVLHFPWLKEELEKRGVRLVWNSKN", "length": 949 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X05-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4F", "gene_name": "Nlrp4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFISDFGLIWYLRELNKKEFMKFKDFLIQEILELKLKQVSSTKVKKASREDLANLLLKCGENQAWDMTFRILQKINRKDLTERATGAIVGNPNLYRDHLKKKLTHDCPKKFNVRIQDFIKETFIQNDXDAFENLLISKGTERKPHMVFLKGMAGVGKTLMLKNLMLAWSKGLVFQNKFSYAFYFCCQDVKQLKTASLAELISREWPSPSAPIEEILSQPEKLLFIIDSLEGMEWDLTKQESELCDDCMEKQPVSTLLSSLLRRKMLPESSLLLSTTPETFEKMEDRIQCTDVKTATAFDERSMKIYFHRLFQDRKRAQEAFSLVRENKQLFTICQVPLLCWMVATCLKEEIEKGGDPVSLCRRTTSLYTTHIFSLFIPQSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFGKEALRRNGIFDSDIPTLLDIGMLGKIREFENSYIFLHPSVQEVCAAIFYMLKRHVEHPSQDVKNIETVLFMFLKKVKTQWIFLGCFIFGLLQKSEQEKLGVFFGHRLSKNIHHKLYQCLETLSGNAELQEQIDGMRLFSCLFEMEDEAFLVKAMNCMQQINFVAKNYSDFIVAAYCLKHCSTLKKLSFSTENVLNEGDQSYMEELLICWNNMCSVFVRSKDIQELRIKDTNFNEPAIRVLYESLKYPSFTLNKLVANNVSFGDNHVLFELIQNSSLQYLDLSCSFLSHNEVKLLCDILNQAECNIEKLMIAHCKLSPDDCKIFGSILMSSKSLKVLNLASNNLNQGISSLCKALCHPHCTLEYLVPRSNHCIVNFLLKLSCCGITERGCQDLAEVLKNNQNLKYLHVSYNKLKDTGVMLLCDAIKHPNCHLKDLQLEACEITDASNEELCYAFMQCETLQTLNLMGNAFEVSRMVFFPRKSELMLFIFLHLSRLWITDFDNEFQAFLLSVKKKNHFLTIRGSVEADGEKKGGDSDARTMGELSNEI", "length": 959 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X19-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4E", "gene_name": "Nlrp4e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKELLQQEILQLGLKHISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRQDLMERAGREIAGHSKLYQVHLKKKLTHDYARKFNIKDQDSLKQKFTQDDCDHFENLLISKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPNASAPIEEILSQPEKLLFVIDNLEVMECDMSEWESELCDDCMEKQPVNILMSSLLRRKMLPESSFLVSATPETFEKIEDRIECTNVKMMAGFNESSIKVYFYSLFQDRNRTQEIFSLVRENEQLFSVCQVPVLCWMVATCLKKEIEKGRDPVSICRRITSLYTTYIFNLFIPHSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFAEEALRRNGIMDSDISTLLDVRILEKSKESEKSYIFLHPSIQEVCAAIFHLLKSHVDHPSQDVKSIEALIFTFLKKVKIQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNKELQEQIDGMKLFYCLFEMDDEAFLPQVMNCMEQIKFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNILSEGQEHSYTEKLLICWHHVCSVLTSSKDIHVLQVKDTNFNERAFLVLYSHLKYPSCILKVLEVNNVTLLCDNRLLFELIQNQRLQLLNLSLTFLSHNDVKLLCDVLNQAECNIEKLMVADCNLSPDDCKVFVSVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLAKCSLSEECWHYLSEVLRRNKTLTHLDISFNDLKDEGLKVLCGALTLPDSVLISLSVRYCLITTSGCQDLAEVLRNNQNLRNLQISNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASSFTHCKTLLGINLQENALDHSGLVALFEAMKQQQCTVNLRGLRITDFDKETQEFLMAEKEKNPYLSI", "length": 978 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X22-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9B", "gene_name": "Nlrp9b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSSGYGLLKLLQKLSDEEFQRFKELLREEPEKFKLKPISWTKIENSSKESLVTLLNTHYPGQAWNMMLSLFLQVNREDLSIMAQKKKRHKQTKYKKFMKTTFERIWTLETNTHIPDRNYHLIVEVQYKALQEIFDSESEPVTAIVAGTTGEGKTTFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKRLPTQIVLSSLLQKIMLPGCSLLLELGQISVPKIRHLLKYPRVITMQGFSERSVEFYCMSFFDNQRGIEVAENLRNNEVLHLCSNPYLCWMFCSCLKWQFDREEEGYFKAKTDAAFFTNFMVSAFKSTYAHSPSKQNRARLKTLCTLAVEGMWKELFVFDSEDLRRNGISESDKAVWLKMQFLQTHGNHTVFYHPTLQSYFAAMFYFLKQDKDICVPVIGSIPQLLGNMYARGQTQWLQLGTFLFGLINEQVAALLQPCFGFIQPIYVRQEIICYFKCLGQQECNEKLERSQTLFSCLRDSQEERFVRQVVDLLEEITVDISSSDVLSVTAYALQKSSKLKKLHLHIQKTVFSEIYCPDHCKTRTSIGKRRNTAEYWKTLCGIFCNLYVLDLDSCQFNKRAIQDLCNSMSPTPTVPLTAFKLQSLSCSFMADFGDGSLFHTLLQLPHLKYLNLYGTYLSMDVTEKLCAALRCSACRVEELLLGKCGISSKACGIIAISLINSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLQSLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCFLTSQCCEEISAVLICNRNLKTLKLGNNNIQDTGVRQLCEALSHPNCNLECLGLDLCEFTSDCCKDLALALTTCKTLNSLNLDWKTLDHSGLVVLCEALNHKRCNLKMLGLDKSAFSEESQTLLQDVEKKNNNLNILHHPWFEAERNKRGTRLVWNSRN", "length": 1003 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6B966-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "Nlrp14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTEDDEMEYEASKEETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITPKDQNLLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLNGKEISQVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFALCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVGCVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQDTEYENCYMFTHLHVQEFFAALFYLLRENLEEQDYPSEPFENLYLLLESNHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVRVDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLDTAEMCLEGAAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLNGCQDFTFLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTKSKRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHNRSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNNSNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNNKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECPNTESGCWWNYF", "length": 993 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTR0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9", "gene_name": "NLRP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESFFSDFGLLWYLKELRKEEFWKFKELLKQPLEKFELKPIPWAELKKASKEDVAKLLDKHYPGKQAWEVTLNLFLQINRKDLWTKAQEEMRNKLNPYRKHMKETFQLIWEKETCLHVPEHFYKETMKNEYKELNDAYTAAARRHTVVLEGPDGIGKTTLLRKVMLDWAEGNLWKDRFTFVFFLNVCEMNGIAETSLLELLSRDWPESSEKIEDIFSQPERILFIMDGFEQLKFNLQLKADLSDDWRQRQPMPIILSSLLQKKMLPESSLLIALGKLAMQKHYFMLRHPKLIKLLGFSESEKKSYFSYFFGEKSKALKVFNFVRDNGPLFILCHNPFTCWLVCTCVKQRLERGEDLEINSQNTTYLYASFLTTVFKAGSQSFPPKVNRARLKSLCALAAEGIWTYTFVFSHGDLRRNGLSESEGVMWVGMRLLQRRGDCFAFMHLCIQEFCAAMFYLLKRPKDDPNPAIGSITQLVRASVVQPQTLLTQVGIFMFGISTEEIVSMLETSFGFPLSKDLKQEITQCLESLSQCEADREAIAFQELFIGLFETQEKEFVTKVMNFFEEVFIYIGNIEHLVIASFCLKHCQHLTTLRMCVENIFPDDSGCISDYNEKLVYWRELCSMFITNKNFQILDMENTSLDDPSLAILCKALAQPVCKLRKLIFTSVYFGHDSELFKAVLHNPHLKLLSLYGTSLSQSDIRHLCETLKHPMCKIEELILGKCDISSEVCEDIASVLACNSKLKHLSLVENPLRDEGMTLLCEALKHSHCALERLMLMYCCLTSVSCDSISEVLLCSKSLSLLDLGSNALEDNGVASLCAALKHPGCSIRELWLMGCFLTSDSCKDIAAVLICNGKLKTLKLGHNEIGDTGVRQLCAALQHPHCKLECLGLQTCPITRACCDDIAAALIACKTLRSLNLDWIALDADAVVVLCEALSHPDCALQMLGLHKSGFDEETQKILMSVEEKIPHLTISHGPWIDEEYKIRGVLL", "length": 991 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W24-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "NLRP14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSSSSSFFPDFGLLLYLEELNKEELNTFKLFLKETMEPEHGLTPWNEVKKARREDLANLMKKYYPGEKAWSVSLKIFGKMNLKDLCERAKEEINWSAQTIGPDDAKAGETQEDQEAVLGDGTEYRNRIKEKFCITWDKKSLAGKPEDFHHGIAEKDRKLLEHLFDVDVKTGAQPQIVVLQGAAGVGKTTLVRKAMLDWAEGSLYQQRFKYVFYLNGREINQLKERSFAQLISKDWPSTEGPIEEIMYQPSSLLFIIDSFDELNFAFEEPEFALCEDWTQEHPVSFLMSSLLRKVMLPEASLLVTTRLTTSKRLKQLLKNHHYVELLGMSEDAREEYIYQFFEDKRWAMKVFSSLKSNEMLFSMCQVPLVCWAACTCLKQQMEKGGDVTLTCQTTTALFTCYISSLFTPVDGGSPSLPNQAQLRRLCQVAAKGIWTMTYVFYRENLRRLGLTQSDVSSFMDSNIIQKDAEYENCYVFTHLHVQEFFAAMFYMLKGSWEAGNPSCQPFEDLKSLLQSTSYKDPHLTQMKCFLFGLLNEDRVKQLERTFNCKMSLKIKSKLLQCMEVLGNSDYSPSQLGFLELFHCLYETQDKAFISQAMRCFPKVAINICEKIHLLVSSFCLKHCRCLRTIRLSVTVVFEKKILKTSLPTNTWDGDRITHCWQDLCSVLHTNEHLRELDLYHSNLDKSAMNILHHELRHPNCKLQKLLLKFITFPDGCQDISTSLIHNKNLMHLDLKGSDIGDNGVKSLCEALKHPECKLQTLRLESCNLTVFCCLNISNALIRSQSLIFLNLSTNNLLDDGVQLLCEALRHPKCYLERLSLESCGLTEAGCEYLSLALISNKRLTHLCLADNVLGDGGVKLMSDALQHAQCTLKSLVLRRCHFTSLSSEYLSTSLLHNKSLTHLDLGSNWLQDNGVKLLCDVFRHPSCNLQDLELMGCVLTNACCLDLASVILNNPNLRSLDLGNNDLQDDGVKILCDALRYPNCNIQRLGLEYCGLTSLCCQDLSSALICNKRLIKMNLTQNTLGYEGIVKLYKVLKSPKCKLQVLGLCKEAFDEEAQKLLEAVGVSNPHLIIKPDCNYHNEEDVSWWWCF", "length": 1093 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W25-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 13", "gene_name": "NLRP13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFSVITCPNGGTNQGLLPYLMALDQYQLEEFKLCLEPQQLMDFWSAPQGHFPRIPWANLRAADPLNLSFLLDEHFPKGQAWKVVLGIFQTMNLTSLCEKVRAEMKENVQTQELQDPTQEDLEMLEAAAGNMQTQGCQDPNQEELDELEEETGNVQAQGCQDPNQEEPEMLEEADHRRKYRENMKAELLETWDNISWPKDHVYIRNTSKDEHEELQRLLDPNRTRAQAQTIVLVGRAGVGKTTLAMQAMLHWANGVLFQQRFSYVFYLSCHKIRYMKETTFAELISLDWPDFDAPIEEFMSQPEKLLFIIDGFEEIIISESRSESLDDGSPCTDWYQELPVTKILHSLLKKELVPLATLLITIKTWFVRDLKASLVNPCFVQITGFTGDDLRVYFMRHFDDSSEVEKILQQLRKNETLFHSCSAPMVCWTVCSCLKQPKVRYYDLQSITQTTTSLYAYFFSNLFSTAEVDLADDSWPGQWRALCSLAIEGLWSMNFTFNKEDTEIEGLEVPFIDSLYEFNILQKINDCGGCTTFTHLSFQEFFAAMSFVLEEPREFPPHSTKPQEMKMLLQHVLLDKEAYWTPVVLFFFGLLNKNIARELEDTLHCKISPRVMEELLKWGEELGKAESASLQFHILRLFHCLHESQEEDFTKKMLGRIFEVDLNILEDEELQASSFCLKHCKRLNKLRLSVSSHILERDLEILETSKFDSRMHAWNSICSTLVTNENLHELDLSNSKLHASSVKGLCLALKNPRCKVQKLTCKSVTPEWVLQDLIIALQGNSKLTHLNFSSNKLGMTVPLILKALRHSACNLKYLCLEKCNLSAASCQDLALFLTSIQHVTRLCLGFNRLQDDGIKLLCAALTHPKCALERLELWFCQLAAPACKHLSDALLQNRSLTHLNLSKNSLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTREGCGELANALSHNHNVKILDLGENDLQDDGVKLLCEALKPHRALHTLGLAKCNLTTACCQHLFSVLSSSKSLVNLNLLGNELDTDGVKMLCKALKKSTCRLQKLG", "length": 1043 }, "evidence": [ { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W26-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 10", "gene_name": "NLRP10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGRYNQVLLVAKPSSESPESLACPFPEQELESVTVEALFDSGEKPSLAPSLVVLQGSAGTGKTTLARKMVLDWATGTLYPGRFDYVFYVSCKEVVLLLESKLEQLLFWCCGDNQAPVTEILRQPERLLFILDGFDELQRPFEEKLKKRGLSPKESLLHLLIRRHTLPTCSLLITTRPLALRNLEPLLKQARHVHILGFSEEERARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRVLRSLCSLAAEGIQHQRFLFEEAELRKHNLDGPRLAAFLSSNDYQLGLAIKKFYSFRHISFQDFFHAMSYLVKEDQSRLGKESRREVQRLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQSQNLFSVKSSLSHGPKEEQKCPSVHGQKEGKDNIAGTQKEASTGKGRGTEETPKNTYI", "length": 655 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W28-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 8", "gene_name": "NLRP8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDVNPPSDTPIPFSSSSTHSSHIPPWTFSCYPGSPCENGVMLYMRNVSHEELQRFKQLLLTELSTGTMPITWDQVETASWAEVVHLLIERFPGRRAWDVTSNIFAIMNCDKMCVVVRREINAILPTLEPEDLNVGETQVNLEEGESGKIRRYKSNVMEKFFPIWDITTWPGNQRDFFYQGVHRHEEYLPCLLLPKRPQGRQPKTVAIQGAPGIGKTILAKKVMFEWARNKFYAHKRWCAFYFHCQEVNQTTDQSFSELIEQKWPGSQDLVSKIMSKPDQLLLLLDGFEELTSTLIDRLEDLSEDWRQKLPGSVLLSSLLSKTMLPEATLLIMIRFTSWQTCKPLLKCPSLVTLPGFNTMEKIKYFQMYFGHTEEGDQVLSFAMENTILFSMCRVPVVCWMVCSGLKQQMERGNNLTQSCPNATSVFVRYISSLFPTRAENFSRKIHQAQLEGLCHLAADSMWHRKWVLGKEDLEEAKLDQTGVTAFLGMSILRRIAGEEDHYVFTLVTFQEFFAALFYVLCFPQRLKNFHVLSHVNIQRLIASPRGSKSYLSHMGLFLFGFLNEACASAVEQSFQCKVSFGNKRKLLKVIPLLHKCDPPSPGSGVPQLFYCLHEIREEAFVSQALNDYHKVVLRIGNNKEVQVSAFCLKRCQYLHEVELTVTLNFMNVWKLSSSSHPGSEAPESNGLHRWWQDLCSVFATNDKLEVLTMTNSVLGPPFLKALAAALRHPQCKLQKLLLRRVNSTMLNQDLIGVLTGNQHLRYLEIQHVEVESKAVKLLCRVLRSPRCRLQCLRLEDCLATPRIWTDLGNNLQGNGHLKTLILRKNSLENCGAYYLSVAQLERLSIENCNLTQLTCESLASCLRQSKMLTHLSLAENALKDEGAKHIWNALPHLRCPLQRLVLRKCDLTFNCCQDMISALCKNKTLKSLDLSFNSLKDDGVILLCEALKNPDCTLQILELENCLFTSICCQAMASMLRKNQHLRHLDLSKNAIGVYGILTLCEAFSSQKKREEVIFCIPAWTRITSFSPTPHPPDFTGKSDCLSQINP", "length": 1048 }, "evidence": [ { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BU40-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4A", "gene_name": "Nlrp4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEVLQLGLKQVSWTEVKKASRQDLASLLLKHYEEKPAWDMTFRFFQKINRKDLIERAKREIDGCPKLYRAHMKTKMTHDSSRAFTISIQNFLKEKFTEDDYDCFENLFQSKGTESKPQVVFLSGGAGVGKTLMLKRLMLAWIESPVFLHKFSYIFYFCCREVKQLKTASLAELISREWPGPSAPIEEILSKPEKLLFIIDSLEGMECDLFKWESELCDNCTEKQPVNVLLSSLLRRKMLPESSLLISATPESFEKMENRIEYTHVKIIKGLKERNIKMSFHRLFQDRNRAHEAFSLVRENEQLFTVCQVPVLCWMVATCLKEEIEKGRDPVSICRCTTSLYTTHIFNLFIPQNAHSPSKKSQDQLQGLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPILLDIGMLINIRESEKSYIFLHPSVQEVCAAIFYLLKSHVDHPSQEVKSIEKLMFAFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQIDGMKLFYCLFEMDDDTFLVEAMNCMEQINFVAKDYSDVIVAAHCLKHCFTLKKLSFSTQNVLSGAQEHSYMERLLTAWNHICSVFIISKDIQELRMKDTNLSESAFSVLYNNLKYHNYTLNVLVANNVFFVCEKYLFFELIQNCNLQHLNLSLTILSHSDVKLLCDVLSQAECNIEELVVAACSISSDDCKVFASVLISNKTLKHLNLASNTLDKGIASLCKSLCHPDCILEHLVLANCSLNEKCWDYLSEVLRRNKTLSHLDISSNDLKDEGLKVLCRALTLPDSVLKSLSLRHCLITISGCQDLAEVLRNNQNLVSLQVSNNKLEDTGVKLLCDAIKHPNCHLEDLGLEACELTGACCEDLASTFTQCKTLWAMNLLKNALDYNGLVVLCEALKQQTCATYVLGLQITDFDTETQAFLVAEQEKNPCLRILSSL", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C6J9-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4B", "gene_name": "Nlrp4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLFSDFGFIWYWKELNKIEFMYFKELLIHEILQMGLKQISWTEVKEASREDLAILLVKHCDGNQAWDTTFRVFQMIGRNVITNRATGEIAAHSTIYRAHLKEKLTHDCSRKFNISIQNFFQDEYDHLENLLVPNGTENNPKMVVLQGVAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCHDVKQLQTASLADLISREWPSPSAPMEEILSQPEKLLFIIDSLEGMEWNVTQQDSQLCYNCMEKQPVNVLLSSLLRKKILPESSLLISTSCETFKDLKDWIEYTNVRTITGFKENNINMCFHSLFQDRNIAQEAFSLIRENEQLFTVCQAPVVCYMVATCLKNEIESGKDPVSICRRTTSLYTTHILNLFIPHNAQNPSNNSEDLLDNLCFLAVEGMWTDISVFNEEALRRNGIMDSDIPTLLDIGILEQSRESENSYIFLHPSVQEFCAAMFYLLHSEMDHSCQGVYFIETFLFTFLNKIKKQWVFLGCFFFGLLHETEQEKLEAFFGYHLSKELRRQLFLWLELLLDTLHPDVKKINTMKFFYCLFEMEEEVFVQSAMNCREQIDVVVKGYSDFIVAAYCLSHGSALTDFSISAQNVLNEELGQRGKLLILWHQICSVFLRNKDIKTLRIEDTIFNEPVFKIFYSYLKNSSCILKTLVAYNVSFLCDKRLFLELIQSYNLEELYLRGTFLSHSDVEMLCDILNQAECNIRILDLANCSLCEHSWDYLSDVLRQNKSLRYLNISYNNLKDEGLKALCRALTLPNSALHSLSLEACQLTGACCKDLASTFTRYKCLRRINLAKNSLGFSGLFVLCKAMKDQTCTLYELKLRMADFDSDSQEFLLSEMERNKILSIENGV", "length": 863 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4B8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWNDTCTSHSSMVCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIGRTKMRDSPMSSLKLELLFEPEDGHSEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSDYLQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFFHNSPKEEEEERRGGRPLDQVQCVFPDTHVACSSRLVNCCLTSSFCRGLFSSLSTNRSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSSSQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTNQNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHNHSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNRETKRALEALQEEKPELTIVFEISW", "length": 1033 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WX94-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 7", "gene_name": "NLRP7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQIARGLWILCQALENPNCNLKHLRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATAPPCCDFFC", "length": 980 }, "evidence": [ { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96MN2-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4", "gene_name": "NLRP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQMTLQLELKQIPWTEVKKASREELANLLIKHYEEQQAWNITLRIFQKMDRKDLCMKVMRERTGYTKTYQAHAKQKFSRLWSSKSVTEIHLYFEEEVKQEECDHLDRLFAPKEAGKQPRTVIIQGPQGIGKTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELRELPPTSLADLISREWPDPAAPITEIVSQPERLLFVIDSFEELQGGLNEPDSDLCGDLMEKRPVQVLLSSLLRKKMLPEASLLIAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQLFSICQIPLLCWILCTSLKQEMQKGKDLALTCQSTTSVYSSFVFNLFTPEGAEGPTPQTQHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGERESSYVFLHVCIQEFCAALFYLLKSHLDHPHPAVRCVQELLVANFEKARRAHWIFLGCFLTGLLNKKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFVKQAVNLLQEANFHIIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFKKEDEHSSTSDYSLICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFSGQSVLLFEVLFYQPDLKYLSFTLTKLSRDDIRSLCDALNYPAGNVKELALVNCHLSPIDCEVLAGLLTNNKKLTYLNVSCNQLDTGVPLLCEALCSPDTVLVYLMLAFCHLSEQCCEYISEMLLRNKSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDLASALISNQNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLASVLTCSKTLQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRKTDFDEETQALLTAEEERNPNLTITDDCDTITRVEI", "length": 994 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW", "length": 1036 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9C000-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 1", "gene_name": "NLRP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGLDQTTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS", "length": 1473 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAM1-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Lrrc34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKLQAQYCYLCSENIRKTNPFILNILQKLDEEIEKRPKEKFTVNIAGNNRLDSGQRITGEDFWLLSKTLRNQPCISGVDVRYNLIGDVGAFYAAKLLQKQPSITYLNLMFNDIGPEGGELIAKALHKNKTLKYLRMTGNKIENTGGMLFAAMLQMNSSLEKLDLGDCDLGLQCVIAFSTVLTQNQAIKGINLNRPILYGEQEESTVHIGHMLKENHVLVELHMCKHGMKNYGLQQLCNALYLNSSLRYLDVSCNKITRDGMVFLADVLKSNTTLEVLDLSFNRIETAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMKTNLVLSNIYIWGNKFDEDTCVAYSDLIKSGRLKPDNTDVEPYMVDEHIYLSEVSNGLKRHYYWAPTYGETYMPSSSAGFALVPVGEHL", "length": 415 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NX02-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 2", "gene_name": "NLRP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSSAQMGFNLQALLEQLSQDELSKFKYLITTFSLAHELQKIPHKEVDKADGKQLVEILTTHCDSYWVEMASLQVFEKMHRMDLSERAKDEVREAALKSFNKRKPLSLGITRKERPPLDVDEMLERFKTEAQAFTETKGNVICLGKEVFKGKKPDKDNRCRYILKTKFREMWKSWPGDSKEVQVMAERYKMLIPFSNPRVLPGPFSYTVVLYGPAGLGKTTLAQKLMLDWAEDNLIHKFKYAFYLSCRELSRLGPCSFAELVFRDWPELQDDIPHILAQARKILFVIDGFDELGAAPGALIEDICGDWEKKKPVPVLLGSLLNRVMLPKAALLVTTRPRALRDLRILAEEPIYIRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQTSVLHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYTLEKEEEEDRDGHTWDIGDVQKLLSGVERLRNPDLIQAGYYSFGLANEKRAKELEATFGCRMSPDIKQELLRCDISCKGGHSTVTDLQELLGCLYESQEEELVKEVMAQFKEISLHLNAVDVVPSSFCVKHCRNLQKMSLQVIKENLPENVTASESDAEVERSQDDQHMLPFWTDLCSIFGSNKDLMGLAINDSFLSASLVRILCEQIASDTCHLQRVVFKNISPADAHRNLCLALRGHKTVTYLTLQGNDQDDMFPALCEVLRHPECNLRYLGLVSCSATTQQWADLSLALEVNQSLTCVNLSDNELLDEGAKLLYTTLRHPKCFLQRLSLENCHLTEANCKDLAAVLVVSRELTHLCLAKNPIGNTGVKFLCEGLRYPECKLQTLVLWNCDITSDGCCDLTKLLQEKSSLLCLDLGLNHIGVKGMKFLCEALRKPLCNLRCLWLWGCSIPPFSCEDLCSALSCNQSLVTLDLGQNPLGSSGVKMLFETLTCSSGTLRTLRLKIDDFNDELNKLLEEIEEKNPQLIIDTEKHHPWAERPSSHDFMI", "length": 1062 }, "evidence": [ { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-366", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-366#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCI8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1081, "end_pos": 1083, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1086, "end_pos": 1088, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1089, "end_pos": 1091, "annotation": "n_glycosylation_sequon" }, { "start_pos": 602, "end_pos": 604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 661, "end_pos": 663, "annotation": "n_glycosylation_sequon" }, { "start_pos": 745, "end_pos": 747, "annotation": "n_glycosylation_sequon" }, { "start_pos": 967, "end_pos": 969, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PCI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCI8" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 253, "end_pos": 386, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1081, "end_pos": 1083 }, { "start_pos": 1086, "end_pos": 1088 }, { "start_pos": 1089, "end_pos": 1091 }, { "start_pos": 602, "end_pos": 604 }, { "start_pos": 661, "end_pos": 663 }, { "start_pos": 745, "end_pos": 747 }, { "start_pos": 967, "end_pos": 969 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PCN1-1", "uniprot_ac": "A0A8M9PCN1", "uniprot_id": "A0A8M9PCN1_DANRE", "mass": { "chemical_mass": 328849.0, "monoisotopic_mass": 328849.0 }, "refseq": { "ac": "XP_021322199", "name": "IgGFc-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322199" }, "gene_names": [ { "name": "fcgbp", "type": "recommended", "evidence": [ { "id": "A0A8M9PCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCN1" } ] }, { "name": "fcgbp", "type": "synonym", "evidence": [ { "id": "XP_021322199", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322199" } ] } ], "protein_names": [ { "name": "IgGFc-binding protein", "type": "synonym", "evidence": [ { "id": "XP_021322199", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322199" }, { "id": "A0A8M9PCN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCN1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322199" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCN1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fcgbp", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCN1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-140106-111", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-111", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd19941", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19941", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101887000", "url": "https://www.ncbi.nlm.nih.gov/gene/101887000", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014853", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014853", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036084", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036084", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101887000", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101887000", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PCN1", "url": "https://www.orthodb.org/?gene=A0A8M9PCN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11339:SF244", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11339:SF244", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01826", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01826", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08742", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08742", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322199", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322199", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PCN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-140106-111", "url": "https://zfin.org/ZDB-GENE-140106-111", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGANLLPVCVVIFLFWDGIQARSAGQEFATAFMQNYVSPFDLPLFQLYITCLNYNCLVKVYIPGLRFTQEVQLTSGQGITVTLPNEVELSGTKRSRNTVSIQSSKDITVSALNSKQYTADTSLVYPLSEWGTEYFVFTPTNSPPSMLKEFVLINGKEQNTVEVFLRAAVRFEGRLYAVGSKLVVVLEPFENVQIQSQGDLTGSRISSQLPIAVYSGHMCTWWFSKCNHVYEQLLPVQSWGTQYLVAPLSIQTQFDSIYIQASQSTNITVQFGRTTLTNVLQRGLILEYKIQFPDGLNIMADGGIQVFFLFNGLRTSSGVIYDPFLVNVQPSNRFCSSYAVDGIAGFGNRALLIVPTREQAGIQFDGSSVPGNIQWRVIKNSNYSWTELIYQTGAGQHKITHPSASFGVYSIGFDQANGYGAPAPCTDPVALASPRSCFGIICNEDEDCMMKGSFPVCVKKPLGICWAMGDPHYSTFDQRYFDFMGTCTYVVTKNCQKNDSLPAFEVLARNENRGDTRVSYVAQVTVHIGGITISVDSSKPGKVQIDQILWSLPVILDDVGVNIFQSGSFVSILFSFGLNVQYDWSHYLTVSLPAAFMNKVCGLCGNFNGDPTDDFTMPSSTQAPNSTVFGQSWKVQNLTLDKGCRDDNGGHECDAQALQQWQTENYCGLLMKDPFSQCHSVIDPNIYIRNCVYDVCMADGSGSYLCKALEVYASVCQRVGIQLTKWREAANCTYRCPENSHYESCGSACPLTCMDLKSHKNCTLPCIETCTCDPGFVLSGSKCVASTQCGCSYNGRYVPAGEAFWADNACQRLCHCSVEGGLLKCQDASCGAGLRCEVVNGVTGCYPFLQSTCMALGDPHYYTFDGKFFDFQGSCVYQLVGVCVSAPGLVPFNVLVQNEFRGSRAVTFTKLLEIKVYNISIVIDKEYAGFVTVNGVLLNLPFNLLQGQVSVFRSGFYAVVQTSFGLKVTFDWNSFATVTVPSTYMGAVCGLCGNYNGNPEDDLAVKGTTSLSYGAMEFGASWLVAQIPGCAHGCTDNCQTCDPSKMSLYGTSDYCGLLRDPQGPFGDCHTILNPGAFFEDCVYDVCLYGGRRDILCQAITTYASSCQAMGKTISPWRSAEFCGVQCPLHSHYELCGSGCEVTCESLAPPVGCRSLCTEGCVCDQGFIRSGDRCVPLAQCGCVYGSRYYLLYQKFYPGNSCEEVCTCSPDGLVVCNKISCGPFEKCELVDGVQKCQPIGKAVCQASGDPHYVTFDGRLFDFQGTCRYILAQSCGVEWTNLTYFSIQVENERWTPNRVYKVSVTKQVAVSLYGSTYVLRQNQPQILVNGVLTNLPYSSNSLNGSLVRAYKDGVNYIIETGFGLKVTYDLVYYVTVTIPGNYRNKTCGLCGVFDGNPSNDFRLPDGNITNDPTIFGRAWKVDVPGSVCEEDGCVTGTCLNCDPQLKAIYEKPPYCGVLIDPNGPFSACHVVLNPAAYLKDCVFDTCVSGGSSKVVCDSVARYAINCHTAGVNIQNWRTDSFCPMLCPAHSHYELCSDVCSAACPGLTSIIQCPKTCTEGCACDRGFLFNGQICVEHRQCGCYEQGRTFKAGEVAYLNYCEQKCQCDPGTGLTCEKSNCPNGTECLLRDGVWNCSYQDPCKNIRCREKETCSVESGRAVCVPLYRSSCWAWGDPHYHTFDGYDYDFQGTCRYVLSKTCGLLSGLEPFSVTQSNENRGSPAVSFVREVEVIVYGNTLTLVNHQMAQIMVDGLLFYLPLDLHDGRVRVRQSGTAALLETDFGLSVSYDWNSKVVLQLPSSYYGLVCGLCGNFNNNNADELRDPTGSLLPGVYQWAKSWRAENSSTSACQDGCDTNCPVCPPELVALYKTDTFCGLLTSAGQSVFNACYAKVNPQAFQQSCVFDLCSNNGDRRLLCQALETYVQRCRQEGVIITDWRRKFNCSMTCPPNSHYEARTSPYAVTCSHPDQPQNCTDTCVEACVCDSGFVLSADTCVPTNQCGCSFEGVYYQPGQTFWADNQCLRLCECDRNLSVVVCRESSCPAGERCSVVDGKRRCQPMSTGECVASGDPHYRTFDGLRFDFQGTCVYQLAALCVYKEGLVPFNVTVQNDHLWGNAVSFTKTVNVSVNGFSITMTREHPNQILVDGQLADLPFLLKGMLIVFRSGNTAVLKTNFGLQVTFDWFSMARVSLPSNYSGAVCGLCGNFNGDVQDDFVMRNGTSAPDSGSLGQSWQVSAIPDCTSAGCLGIGCSTCPSTQRENAECYCEIIANRTGPFRECHTYIDPGPYVEDCILDTCQIQGYQGVLCGAVAAYASACQSQSITVYPWRNATFCPLSCPPNSHYNSCSPGCTETCAYLSEHNCTRPCAEACQCDRGFIWSGLTCVPQTECGCFYQGRYYKKYQTFYNHPQCMQLCMCGENGNVSCQTSSCGPGEACRIADGLFGCHPVSFGQCVATGDPHYISFDGRRFDFQGTCVYTLAKVCEWSVGQLRNFSVDTQNEQFGNRGVSVIRSLTVNVYNFTITIRRGERWRVIVNNESVNLPSSLDHITISQVGFNIIIQTDFGLRVQYDTGYHAEVHIPSSYQNSTCGLCGNYNGNPSDDFMLPNGTQSSSAETFGQAWALKTTSVQCVGGSSPKQCIQSENDRYRRDDACGLMASATGPFSACHDLVNPEPHVINCVFDMCIMDGDRATLCQNLQGYAIICQQAGIQIMPWRNSSFCPADCPANSHYVQCSNNCAKTCASLTGSINSCPNICMEGCQCDEGFLSDGDQCVSVGDCGCVHNGKYLKVGEVSVTETCDMKCSCRAAGVLECVKQACASGDTCDVQNGKRDCYPLQGLCAFDANDQLLSFDGVKATIRQLGAFQMAFLCDEKSPDWFRVVLDVHACASNQSGNMKIVHVFFQDMIITVNNRLHSWVNGRNISYPFMPRKGLSVSFRNEAVVIEKTSILRLTYSVAEGVVLTVSRDLRGNVCGACGNFNGDTADDMTTSSERNSTVMSLDVSSWKAEDFFTCDM", "length": 3001, "header": "tr|A0A8M9PCN1-1|A0A8M9PCN1_DANRE Isoform 1 of IgGFc-binding protein OS=Danio rerio OX=7955 GN=fcgbp PE=4 SV=1 CANONICAL=A0A8M9PCN1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PCN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCN1/entry#A0A8M9PCN1-1", "sequence": { "sequence": 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"length": 3001, "header": "tr|A0A8M9PCN1-1|A0A8M9PCN1_DANRE Isoform 1 of IgGFc-binding protein OS=Danio rerio OX=7955 GN=fcgbp PE=4 SV=1 CANONICAL=A0A8M9PCN1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1372, "start_aa": "Thr", "end_pos": 1372, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1372", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101887000", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101887000", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of BMP signaling pathway", "id": "GO:0030513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030513", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1278, "end_pos": 1280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1340, "end_pos": 1342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1381, "end_pos": 1383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1404, "end_pos": 1406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1617, "end_pos": 1619, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1629, "end_pos": 1631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1836, "end_pos": 1838, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1934, "end_pos": 1936, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1964, "end_pos": 1966, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2022, "end_pos": 2024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2096, "end_pos": 2098, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2116, "end_pos": 2118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2185, "end_pos": 2187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2209, "end_pos": 2211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2261, "end_pos": 2263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2319, "end_pos": 2321, "annotation": "n_glycosylation_sequon" 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PCP0-1", "uniprot_ac": "A0A8M9PCP0", "uniprot_id": "A0A8M9PCP0_DANRE", "mass": { "chemical_mass": 47520.0, "monoisotopic_mass": 47520.0 }, "refseq": { "ac": "XP_021322209", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322209" }, "gene_names": [ { "name": "LOC110437936", "type": "recommended", "evidence": [ { "id": "A0A8M9PCP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0" } ] }, { "name": "LOC110437936", "type": "synonym", "evidence": [ { "id": "XP_021322209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322209" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PCP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021322209", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322209" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322209.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322209" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCP0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCP0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110437936", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0", "locus": {} } ], "crossref": [ { "id": "A0A8M9PCP0", "url": 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"id": "PTHR24393:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322209", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322209", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PCP0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRHGKRDQMEANEQREELNEEDERRNFETQRTKTTHLHSCLQCGKSFRRKAKLKKHRKTHAGEKPYTCTECGKSFSQLDSYKRHQKTHEDKRDHECLQCGKSFTTAGNLKIHQRIHTGEKPYKCSYCEKSFSQSGDLRRHERIHTGEKPYHCTQCGHDFRSSSELQNHMRIHRNEKPYACLFCEKRFSQLGDCKRHQKTHTGERDHECLECGKSFNRADNLKIHQMIHTGEKPHKCSYCEKSFIQSSQLKKHERIHTGEKPFTCTQCGHDFRSSSNLKQHMRIHTNEKPYACLFCKKRFSDLGHCKQHQKTHTGERDHVCLDCGKSFNRSGSLKIHQMIHTGEKPHKCSYCEKSFIRSSELKSHERIHTGERLYCCPPCQKSFRWSESLLRHMRKCKWSQ", "length": 401, "header": "tr|A0A8M9PCP0-1|A0A8M9PCP0_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC110437936 PE=3 SV=3 CANONICAL=A0A8M9PCP0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PCP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0/entry#A0A8M9PCP0-1", "sequence": { "sequence": "MKRHGKRDQMEANEQREELNEEDERRNFETQRTKTTHLHSCLQCGKSFRRKAKLKKHRKTHAGEKPYTCTECGKSFSQLDSYKRHQKTHEDKRDHECLQCGKSFTTAGNLKIHQRIHTGEKPYKCSYCEKSFSQSGDLRRHERIHTGEKPYHCTQCGHDFRSSSELQNHMRIHRNEKPYACLFCEKRFSQLGDCKRHQKTHTGERDHECLECGKSFNRADNLKIHQMIHTGEKPHKCSYCEKSFIQSSQLKKHERIHTGEKPFTCTQCGHDFRSSSNLKQHMRIHTNEKPYACLFCKKRFSDLGHCKQHQKTHTGERDHVCLDCGKSFNRSGSLKIHQMIHTGEKPHKCSYCEKSFIRSSELKSHERIHTGERLYCCPPCQKSFRWSESLLRHMRKCKWSQ", "length": 401, "header": "tr|A0A8M9PCP0-1|A0A8M9PCP0_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC110437936 PE=3 SV=3 CANONICAL=A0A8M9PCP0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110437936", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437936", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", 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"pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCP0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCP0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCP0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCP0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PCP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCP0" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 66, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 329, "end_pos": 331 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PCT1-1", "uniprot_ac": "A0A8M9PCT1", "uniprot_id": "A0A8M9PCT1_DANRE", "mass": { "chemical_mass": 558766.0, "monoisotopic_mass": 558766.0 }, "refseq": { "ac": "XP_021322239", "name": "uncharacterized protein si:ch211-286b4.4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322239" }, "gene_names": [ { "name": "si:ch211-286b4.4", "type": "recommended", "evidence": [ { "id": "A0A8M9PCT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCT1" } ] }, { "name": "si:ch211-286b4.4", "type": "synonym", "evidence": [ { "id": "XP_021322239", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322239" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch211-286b4.4 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PCT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCT1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch211-286b4.4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322239", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322239" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322239.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322239" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCT1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCT1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-286b4.4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCT1", "locus": {} } ], "crossref": [ { "id": "100005359", "url": "https://www.ncbi.nlm.nih.gov/gene/100005359", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100005359", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005359", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PCT1", "url": "https://www.orthodb.org/?gene=A0A8M9PCT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47236", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47236", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47236:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47236:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322239", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322239", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PCT1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCQ3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERYFLFFLFYLTWSGFRLKRNVFVSGSDERPECSECLICCNQTQTECPEGSYFSSGICLECPAGHYCFGNVSAPRKCPAGMFNPYTGKSSVQDCQPCVAGLVSTEDRMECRLCPAGFSCDSTSSNLTACLSGQFSPEGLSRCLPCPFGFVCIDGFQMKCGPGEEPNLNQTECVECAEGYYSTLCSAQCQQCPTGSHCPDKKMSAPLPCPVGYYSDMPGQTECKKCNGSSVCRSTVTPFWSRGQSHLGPRSRQLISCPSGTYRDGERSDCVVCPAGHYCVANIAIQCPEGTYGPKEGLQRERDCAICPAGFYCLEGTSRRPSSQFLCPQGYYCEEGTGVPHGSPCPAGTAGGQLGQTSRAACKRCAEGRYCPTGSAGPGLLCARGRYCPAGTLSEILCPQGTFTPHQGALSVKDCLKCPPGFYCPEGTSDPLPCQPGTFNPLEGQDALADCRPCYPGKACTQVALKFPDVDCMPGFVCPPGSSRPNEPSNACPPGTLSNRTDLTDLSQCHQCPPRYACYRGTGGIQRPPLFCFPGHYCPAGTMFPTQHKCPAGTWSDRSGLESERECRPCPKGWYCLAGVGAPSGRCNSGNYCPEGTLYGSQHPCPSGTYSTNIGNAAKEDCQVCPEGHYCKEGTSKPTSCPPATFRKIKGGRRAEDCSVCPAGYYCPHPATIHPKVCGTGSFSDEGSEVCLPCLPGHYCSNETTSEEAMLRVMVCPPGFLCSQGLDREPQRSAVFCPIGFYCPGGSVDPNPVPCPKGTYSRQPGLRDPSDCTKCPAGKYCYTENPQEEPIIEPTGNCPDGYFCPPGTGHPNSFPCQSGFFRNESYGHEGETCVKCPPGHYCPFLATHTPTVCPQGFYCVDGSSSPEPCEEGTYGSRTALSEASQCTPCSGGKYCSGLGKSEPTGDCEAGFYCRQGSASPIPPDGHEGGVCPAGSFCPLGSVHPHPCPSGTYSNSTGLQHAEQCVRCPPGYYCLGTNSTSPTGPCSAGYYCSGGSATPVQHETEEGHFSLEGAVRAEPCPLGTFQPGRGHSSCLECQSGKLCNKTGLSQQPLCPPGHFCPAGSLIAHPCPPGTYTASSGAEDLQHCSPCDAGQYCHSPGLTAPQGPCEAGFYCTGGSHVATPFSSRFGDICPMGYYCPAGTRHPHEFPCPPGTWSNALGSKSVSSCWLCPAGFYCNSSGLIQPSGNCAPGFYCAGGAKTAMPDDGLTGNRCPTRYYCPQGCASPLHCPDGTHSNSTGSAECSDCPTGWLCLEGEDLQLCPKGHYCVGGTVEDILPCPPGTYSPKAGQSQVEQCLLCSAGMYCEDWGLVEPTGPCQAGYFCFAGINFQNPDANISTGVGGSCPVGHYCPEGTSLPLPCPLGTFSNSLYVTAVSGCSVCPAGLFCGSVGLSRPSGPCREGFYCPAGASSSTGSNSEGGLCPQAHFCPAGSAVPVPCPAGTYTNLTGQIKCSLCHAGYYCPESTSNYNLYPCPAGFYCPDGTKHANQFPCPRGYYNPELMTHSLDSCLPCPPGHFCEKEHLSAVSGKCKAGWFCVSAAWNPQPFDLDNYTNANCLCPASSTGGRCQEGFYCPSGTSEPLPCPPGAFCNATGLALPSGPCSPGYYCTREASFSRPTDGITGNICPPGTYCDEGSSAPQPCPAGTFSPSAGLMSQEECQACRAGHYCATTGLQAPTAPCRQGYWCLPGQTDDLALPCLVGHYCPPGSPVPILCPSGTYQDKQKQANCTICEAGFYCDENFGAANMSAMQPCPKGHYCPEGTGYAEQFPCPVGTYNPRELMDSQRNCLLCPPGHYCPHVGLEEPTGLCLAGFWCKQGSHSSSPMGGPTGDVCPVGHYCPKGTASPVPCPVGTWSNSTGLRIAEDCQSCPGGFYCASTGLNGPSGLCSEGFYCTEKAESPTPIDGITGHVCPEGHYCPPGATRPVPCHSGTFVTVPQASQCWACTAGWYCADGGRLLCPAGFYCPEGTGYDIRPCPAGTYSPDSGLISLSECRACDGGHYCSLQNSSSVTGQCSEGYYCAQGNISPQPYTQNTGVGGLCPVGHFCPQGTAQPQPCPEGTFSNRTKLVKVEECLSCPAGHYCNISGLTSPSGECWEGFYCTKGAVLPNSPITDHRGGPCPTGYFCWKGSGAPQACPEGSISSREGQNSCSLCPQGYYCPANGSSSEGIECPMGHYCPMGTHLQNQHPCPAGTINPHMRMASREDCLPCPSGFFCESAGRSAVSGPCAAGHFCLSGATSPTPVNAGAGGECPRGHYCPVGSSSPEPCPLGHFSNSSRNTKLSDCLLCPPGFACSSRGLSSPSHVCQMGYFCPQGQNSSQPANYICSSGYMCPPGSPVQFPCPVGTYQNLHGQAECLLCPAGYFCAASDTVTGGTSIPVPCPAGYYCPPGSDSGMHFPCPVGTFNGQPGLSSKDQCVPCPPGKYCSSSGLDAPTGNCSPGYVCTQGASLSEPVGDSTGGRCTPGFFCPAGASHMEPCPLGTFGSLEGAASVEMCQSCTPGHYCAESGLTSPSGPCSPGYYCVQGSHTPAPQYYNNTVCEEPVGHSAEDIYSHLQFIGDICPAGHYCPIGSVRPEPCPPGFFQGQRGAVSETDCQPCTSGYYCPDWGQSSAELLCPEGSFCPPGSPTGHQPERQCPSGHACPYGSVEPAICLPGTYQPLPSQPSCQPCPSGFYCLEGCTSPLPCPAGTASVIEGLQSQRDCSPCPPGFYCNTSALISPSGPCSAGHFCSSGATEPAPVSQMYGDICPAGHYCPEQSSAPLPCPVGFILRDKGATSFNDCSSCPPSRYCAAPGSTQPSGSCAPGHYCVKGADTSRPQATLSQQTCFCDLIPSSHLQKYDLCHLKHNITCAIHIPGDGAVWTDLDPRPLLESEAPLQIREPCTGFKGDLCPTGSYCPVGSSVPQPCDSGSYCNQTGLYTPVGLCFAGFFCPTGSSNPSAVLCPPGHYCPQGTPRPLSCPQGTVRSSAGGSSAGDCLECPPGYFCEQRGLTEPSGLCSEGYYCPGGQNTSRPAEYVCRAGHFCQRGIIMERPCFPGTFQPSPGQHRCDVCPARFFCPEHGMTHPFPCQPGYYCPVGASNQHPCPPGGFGNRSGLADSSECSQCDPGTYCMGSGNVSPTGPCSAGFLCFGGAVLSSPNDNETGMLCPSGFYCPAGSFAGIPCPKGTFSNSSQLSKISQCQNCTPGFYCSEPGLTAVSGPCLPGYYCSEGSPSAAPVSAVYGSVCPPGHYCVVGSAVPAPCPVGTRRPDSRGKATDDCMPCPGGQFQDQRGQSECKPCPTGFHCINLTSGSTGVSSPIICPEGFYCPNETQSGNPVPCPKGTYSDSLGLISAEQCLVCPMGYFCGSVGLSNPSGACAPGFLCFVQATVPNPTDNSTGSLCPPGAFCLLGTRAGECSEGYYCDWGSSSPEQSLCPAGFYCPAGTNKPLACTGGTFSSVMGNSHRENCEPCPLGFYCQGDAVAEPLPCPPGHFCPLSTSQGTQFPCPPGTMQPQSGTASVEECLPCPSGMFCASHGLSEPTGRCQDGFHCPSGATSPDGTGNTIESTGNNICPPGHYCPTGIGSPLPCPAGTFSSSPGLSGPEQCQPCPPGYFCEQTAMVHPSQAALCDAGYVCINGSRSARPVDGLQGYICPSGHSCPIGAPLEVPCEPGTYSSVPGAARCLLCPAGTMCPSPGTLEPSPCPMGHFCPVGTAEAVPCPVGTLGQGTRAQSEAACVPCPTGLYCSSAGTSQPQGQCQQGYFCQGGSPNPAPLNTTGYLRNGPCPQGHFCPSGTLMPLPCPAGSIRNLTGGYSLESCLPCPAGHYCASEGLDAPTGPCAAGFYCPVDFSSTTAHAFLCPKGHFCPLGSPLALPCPTGQYQPNPGSDNCIPCRPGFYCEEAIIGDPRPCPPHSYCPAATMVPQPCPNGTYTPSEVGGLQEERECLPCPSGKFCKAGQVKGLCAAGFLCISGSSDFTPQSSFLINRDQCEWGAQCAGPCPAGYYCPEGTEEPLSCPSNTLRENPGASSLRDCLPCPPKQWCREGDPIPRMCPPGYYCDGIADYESEGRPGPRVCPMFTYRPTSGAGSKGDCVTCPAGTFCNSTGLTDFSSFPCPPGYWCSGTGFPVFCPAGTMRPQAWAASASQCELCPPGTHCPDPRTTGQPNTAGIPCRSSYQCPAGSVTEILCRAGSYCTPQTGEPTPCPAGYYCPEGSHTYSSPQQVCTFPNYCPANSSAMLSCPDGWMPLNTSGLRKSQESSCVQCGAGTYRPSRSPHLQCLLCPPGHHCPAGSHHYSDQPCPVGYFCPQGISDPVPCPPGSYGNRSSAESLEQCHKCPPGTFNHLNAQRACFPCGSSSTSDAGASSCTCTGKNRAFQYSDGSCLCKTGFVFYNELDFKSSSADSPLDCQPEVKKRCGAGQARLASTMECVAPSTYSCNITCGPQGGTLDVEMGICQCERYVSVEELCNSSCVSALPELSVRLDTNGQLTLRIKTTDESKTWSRNMINVLGPDVHIKNIGRIHFAQFAPEGVFGWILKDPILIDSLLREPVEVLEKDFRRKRHADQNEVSMPLPRIPNPIACLSPNDMLIFQLTINHTDRHHSHFPVYQKDHLFSSNPGWDFGAFRRLQHLVTHTQLNSSRFAHVFMEPGKYVFLDNAVPDWSLIVVVREQGSECNPTTAAFQPTTPAQLVRHGIVKQHKLNLLPDWGLIIGILSLLVLLIIVLTASALVLRPNRSHLIAQGRPKPKWRSLGEPSVPIEYIYNTDGVDSSESLGLRGVGEGAESEEPAVCKGGFRATLMELEEFNVKTLYDKLEDQNLHLASQMAKHRKDTQEFYKNMCQQIDTLKDTLDNMEPSKLNQLKKILDNDLQVKRETAHAEPWMGLMEAVLRSLDGVLCRMNGEIWQQQDSIATHSHRDTRESELHTVYNQFSPADMTEFKVGADTEAASSDPDQQQSTIPCVSEEELAKIVSLTPLSKTLQEIKECLQTLSQTSETEDVIISSEESEASHLIPVALDSLSPQHFTVFLFGCHVVRLLNRACAFPPVMLLLARAVPVSHCDNLLAYCHKDFYYDTANQILYILEKKLQNAGQFISILLHSMAYISSGSKSLDFMKAFHSAISALSMQLYHYSFTEDQRKGKVGEESIPQAFGTLVEDFFSVKIPIETHFAPNLLAERLQVYKYFKLEQLLQELKPTLKDRHADGQGQSGLKTEVPVLCVEREINRLDEVYQQLSSDLSRPAHTHNPPENNKAKSDSPLQDEQMLLVLKKCPVDQRLKEMRDRLSKLSSGQRSGPDEDIQTLSKCKPDVGGAPEKNMLATGQSSSKKKQSKHMDKDEDKRLTA", "length": 5293, "header": "tr|A0A8M9PCT1-1|A0A8M9PCT1_DANRE Isoform 1 of Uncharacterized protein si:ch211-286b4.4 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-286b4.4 PE=4 SV=3 CANONICAL=A0A8M9PCT1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PCT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCT1/entry#A0A8M9PCT1-1", "sequence": { "sequence": "MERYFLFFLFYLTWSGFRLKRNVFVSGSDERPECSECLICCNQTQTECPEGSYFSSGICLECPAGHYCFGNVSAPRKCPAGMFNPYTGKSSVQDCQPCVAGLVSTEDRMECRLCPAGFSCDSTSSNLTACLSGQFSPEGLSRCLPCPFGFVCIDGFQMKCGPGEEPNLNQTECVECAEGYYSTLCSAQCQQCPTGSHCPDKKMSAPLPCPVGYYSDMPGQTECKKCNGSSVCRSTVTPFWSRGQSHLGPRSRQLISCPSGTYRDGERSDCVVCPAGHYCVANIAIQCPEGTYGPKEGLQRERDCAICPAGFYCLEGTSRRPSSQFLCPQGYYCEEGTGVPHGSPCPAGTAGGQLGQTSRAACKRCAEGRYCPTGSAGPGLLCARGRYCPAGTLSEILCPQGTFTPHQGALSVKDCLKCPPGFYCPEGTSDPLPCQPGTFNPLEGQDALADCRPCYPGKACTQVALKFPDVDCMPGFVCPPGSSRPNEPSNACPPGTLSNRTDLTDLSQCHQCPPRYACYRGTGGIQRPPLFCFPGHYCPAGTMFPTQHKCPAGTWSDRSGLESERECRPCPKGWYCLAGVGAPSGRCNSGNYCPEGTLYGSQHPCPSGTYSTNIGNAAKEDCQVCPEGHYCKEGTSKPTSCPPATFRKIKGGRRAEDCSVCPAGYYCPHPATIHPKVCGTGSFSDEGSEVCLPCLPGHYCSNETTSEEAMLRVMVCPPGFLCSQGLDREPQRSAVFCPIGFYCPGGSVDPNPVPCPKGTYSRQPGLRDPSDCTKCPAGKYCYTENPQEEPIIEPTGNCPDGYFCPPGTGHPNSFPCQSGFFRNESYGHEGETCVKCPPGHYCPFLATHTPTVCPQGFYCVDGSSSPEPCEEGTYGSRTALSEASQCTPCSGGKYCSGLGKSEPTGDCEAGFYCRQGSASPIPPDGHEGGVCPAGSFCPLGSVHPHPCPSGTYSNSTGLQHAEQCVRCPPGYYCLGTNSTSPTGPCSAGYYCSGGSATPVQHETEEGHFSLEGAVRAEPCPLGTFQPGRGHSSCLECQSGKLCNKTGLSQQPLCPPGHFCPAGSLIAHPCPPGTYTASSGAEDLQHCSPCDAGQYCHSPGLTAPQGPCEAGFYCTGGSHVATPFSSRFGDICPMGYYCPAGTRHPHEFPCPPGTWSNALGSKSVSSCWLCPAGFYCNSSGLIQPSGNCAPGFYCAGGAKTAMPDDGLTGNRCPTRYYCPQGCASPLHCPDGTHSNSTGSAECSDCPTGWLCLEGEDLQLCPKGHYCVGGTVEDILPCPPGTYSPKAGQSQVEQCLLCSAGMYCEDWGLVEPTGPCQAGYFCFAGINFQNPDANISTGVGGSCPVGHYCPEGTSLPLPCPLGTFSNSLYVTAVSGCSVCPAGLFCGSVGLSRPSGPCREGFYCPAGASSSTGSNSEGGLCPQAHFCPAGSAVPVPCPAGTYTNLTGQIKCSLCHAGYYCPESTSNYNLYPCPAGFYCPDGTKHANQFPCPRGYYNPELMTHSLDSCLPCPPGHFCEKEHLSAVSGKCKAGWFCVSAAWNPQPFDLDNYTNANCLCPASSTGGRCQEGFYCPSGTSEPLPCPPGAFCNATGLALPSGPCSPGYYCTREASFSRPTDGITGNICPPGTYCDEGSSAPQPCPAGTFSPSAGLMSQEECQACRAGHYCATTGLQAPTAPCRQGYWCLPGQTDDLALPCLVGHYCPPGSPVPILCPSGTYQDKQKQANCTICEAGFYCDENFGAANMSAMQPCPKGHYCPEGTGYAEQFPCPVGTYNPRELMDSQRNCLLCPPGHYCPHVGLEEPTGLCLAGFWCKQGSHSSSPMGGPTGDVCPVGHYCPKGTASPVPCPVGTWSNSTGLRIAEDCQSCPGGFYCASTGLNGPSGLCSEGFYCTEKAESPTPIDGITGHVCPEGHYCPPGATRPVPCHSGTFVTVPQASQCWACTAGWYCADGGRLLCPAGFYCPEGTGYDIRPCPAGTYSPDSGLISLSECRACDGGHYCSLQNSSSVTGQCSEGYYCAQGNISPQPYTQNTGVGGLCPVGHFCPQGTAQPQPCPEGTFSNRTKLVKVEECLSCPAGHYCNISGLTSPSGECWEGFYCTKGAVLPNSPITDHRGGPCPTGYFCWKGSGAPQACPEGSISSREGQNSCSLCPQGYYCPANGSSSEGIECPMGHYCPMGTHLQNQHPCPAGTINPHMRMASREDCLPCPSGFFCESAGRSAVSGPCAAGHFCLSGATSPTPVNAGAGGECPRGHYCPVGSSSPEPCPLGHFSNSSRNTKLSDCLLCPPGFACSSRGLSSPSHVCQMGYFCPQGQNSSQPANYICSSGYMCPPGSPVQFPCPVGTYQNLHGQAECLLCPAGYFCAASDTVTGGTSIPVPCPAGYYCPPGSDSGMHFPCPVGTFNGQPGLSSKDQCVPCPPGKYCSSSGLDAPTGNCSPGYVCTQGASLSEPVGDSTGGRCTPGFFCPAGASHMEPCPLGTFGSLEGAASVEMCQSCTPGHYCAESGLTSPSGPCSPGYYCVQGSHTPAPQYYNNTVCEEPVGHSAEDIYSHLQFIGDICPAGHYCPIGSVRPEPCPPGFFQGQRGAVSETDCQPCTSGYYCPDWGQSSAELLCPEGSFCPPGSPTGHQPERQCPSGHACPYGSVEPAICLPGTYQPLPSQPSCQPCPSGFYCLEGCTSPLPCPAGTASVIEGLQSQRDCSPCPPGFYCNTSALISPSGPCSAGHFCSSGATEPAPVSQMYGDICPAGHYCPEQSSAPLPCPVGFILRDKGATSFNDCSSCPPSRYCAAPGSTQPSGSCAPGHYCVKGADTSRPQATLSQQTCFCDLIPSSHLQKYDLCHLKHNITCAIHIPGDGAVWTDLDPRPLLESEAPLQIREPCTGFKGDLCPTGSYCPVGSSVPQPCDSGSYCNQTGLYTPVGLCFAGFFCPTGSSNPSAVLCPPGHYCPQGTPRPLSCPQGTVRSSAGGSSAGDCLECPPGYFCEQRGLTEPSGLCSEGYYCPGGQNTSRPAEYVCRAGHFCQRGIIMERPCFPGTFQPSPGQHRCDVCPARFFCPEHGMTHPFPCQPGYYCPVGASNQHPCPPGGFGNRSGLADSSECSQCDPGTYCMGSGNVSPTGPCSAGFLCFGGAVLSSPNDNETGMLCPSGFYCPAGSFAGIPCPKGTFSNSSQLSKISQCQNCTPGFYCSEPGLTAVSGPCLPGYYCSEGSPSAAPVSAVYGSVCPPGHYCVVGSAVPAPCPVGTRRPDSRGKATDDCMPCPGGQFQDQRGQSECKPCPTGFHCINLTSGSTGVSSPIICPEGFYCPNETQSGNPVPCPKGTYSDSLGLISAEQCLVCPMGYFCGSVGLSNPSGACAPGFLCFVQATVPNPTDNSTGSLCPPGAFCLLGTRAGECSEGYYCDWGSSSPEQSLCPAGFYCPAGTNKPLACTGGTFSSVMGNSHRENCEPCPLGFYCQGDAVAEPLPCPPGHFCPLSTSQGTQFPCPPGTMQPQSGTASVEECLPCPSGMFCASHGLSEPTGRCQDGFHCPSGATSPDGTGNTIESTGNNICPPGHYCPTGIGSPLPCPAGTFSSSPGLSGPEQCQPCPPGYFCEQTAMVHPSQAALCDAGYVCINGSRSARPVDGLQGYICPSGHSCPIGAPLEVPCEPGTYSSVPGAARCLLCPAGTMCPSPGTLEPSPCPMGHFCPVGTAEAVPCPVGTLGQGTRAQSEAACVPCPTGLYCSSAGTSQPQGQCQQGYFCQGGSPNPAPLNTTGYLRNGPCPQGHFCPSGTLMPLPCPAGSIRNLTGGYSLESCLPCPAGHYCASEGLDAPTGPCAAGFYCPVDFSSTTAHAFLCPKGHFCPLGSPLALPCPTGQYQPNPGSDNCIPCRPGFYCEEAIIGDPRPCPPHSYCPAATMVPQPCPNGTYTPSEVGGLQEERECLPCPSGKFCKAGQVKGLCAAGFLCISGSSDFTPQSSFLINRDQCEWGAQCAGPCPAGYYCPEGTEEPLSCPSNTLRENPGASSLRDCLPCPPKQWCREGDPIPRMCPPGYYCDGIADYESEGRPGPRVCPMFTYRPTSGAGSKGDCVTCPAGTFCNSTGLTDFSSFPCPPGYWCSGTGFPVFCPAGTMRPQAWAASASQCELCPPGTHCPDPRTTGQPNTAGIPCRSSYQCPAGSVTEILCRAGSYCTPQTGEPTPCPAGYYCPEGSHTYSSPQQVCTFPNYCPANSSAMLSCPDGWMPLNTSGLRKSQESSCVQCGAGTYRPSRSPHLQCLLCPPGHHCPAGSHHYSDQPCPVGYFCPQGISDPVPCPPGSYGNRSSAESLEQCHKCPPGTFNHLNAQRACFPCGSSSTSDAGASSCTCTGKNRAFQYSDGSCLCKTGFVFYNELDFKSSSADSPLDCQPEVKKRCGAGQARLASTMECVAPSTYSCNITCGPQGGTLDVEMGICQCERYVSVEELCNSSCVSALPELSVRLDTNGQLTLRIKTTDESKTWSRNMINVLGPDVHIKNIGRIHFAQFAPEGVFGWILKDPILIDSLLREPVEVLEKDFRRKRHADQNEVSMPLPRIPNPIACLSPNDMLIFQLTINHTDRHHSHFPVYQKDHLFSSNPGWDFGAFRRLQHLVTHTQLNSSRFAHVFMEPGKYVFLDNAVPDWSLIVVVREQGSECNPTTAAFQPTTPAQLVRHGIVKQHKLNLLPDWGLIIGILSLLVLLIIVLTASALVLRPNRSHLIAQGRPKPKWRSLGEPSVPIEYIYNTDGVDSSESLGLRGVGEGAESEEPAVCKGGFRATLMELEEFNVKTLYDKLEDQNLHLASQMAKHRKDTQEFYKNMCQQIDTLKDTLDNMEPSKLNQLKKILDNDLQVKRETAHAEPWMGLMEAVLRSLDGVLCRMNGEIWQQQDSIATHSHRDTRESELHTVYNQFSPADMTEFKVGADTEAASSDPDQQQSTIPCVSEEELAKIVSLTPLSKTLQEIKECLQTLSQTSETEDVIISSEESEASHLIPVALDSLSPQHFTVFLFGCHVVRLLNRACAFPPVMLLLARAVPVSHCDNLLAYCHKDFYYDTANQILYILEKKLQNAGQFISILLHSMAYISSGSKSLDFMKAFHSAISALSMQLYHYSFTEDQRKGKVGEESIPQAFGTLVEDFFSVKIPIETHFAPNLLAERLQVYKYFKLEQLLQELKPTLKDRHADGQGQSGLKTEVPVLCVEREINRLDEVYQQLSSDLSRPAHTHNPPENNKAKSDSPLQDEQMLLVLKKCPVDQRLKEMRDRLSKLSSGQRSGPDEDIQTLSKCKPDVGGAPEKNMLATGQSSSKKKQSKHMDKDEDKRLTA", "length": 5293, "header": "tr|A0A8M9PCT1-1|A0A8M9PCT1_DANRE Isoform 1 of Uncharacterized protein si:ch211-286b4.4 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-286b4.4 PE=4 SV=3 CANONICAL=A0A8M9PCT1-1" }, "locus": {} }, { "isoform_ac": "A0AC58HCQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCT1/entry#A0AC58HCQ3-1", "sequence": { "sequence": 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HYSFTEDQRKGKVGEESIPQAFGTLVEDFFSVKIPIETHFAPNLLAERLQVYKYFKLEQLLQELKPTLKDRHADGQGQSGLKTEVPVLCVEREINRLDEVYQQLSSDLSRPAHTHNPPENNKAKSDSPLQDEQMLLVLKKCPVDQRLKEMRDRLSKLSSGQRSGPDEDIQTLSKCKPDVGGAPEKNMLATGQSSSKKKQSKHMDKDEDKRLTA", "length": 5212, "header": "tr|A0AC58HCQ3-1|A0AC58HCQ3_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-286b4.4 isoform X2 OS=Danio rerio OX=7955 GN=si:ch211-286b4.4 PE=4 SV=1 CANONICAL=A0A8M9PCT1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2232, "start_aa": "Thr", "end_pos": 2232, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2232", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 4159, "start_aa": "Thr", "end_pos": 4159, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr4159", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100005359", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005359", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1043, "end_pos": 1045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1176, "end_pos": 1178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1234, "end_pos": 1236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1332, "end_pos": 1334, "annotation": 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"start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4393, "end_pos": 4395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4423, "end_pos": 4425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4550, "end_pos": 4552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4592, "end_pos": 4594, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4688, "end_pos": 4690, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 702, "end_pos": 704, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" }, { "start_pos": 823, "end_pos": 825, "annotation": "n_glycosylation_sequon" }, { "start_pos": 954, "end_pos": 956, "annotation": "n_glycosylation_sequon" }, { "start_pos": 977, "end_pos": 979, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PCV3-1", "uniprot_ac": "A0A8M9PCV3", "uniprot_id": "A0A8M9PCV3_DANRE", "mass": { "chemical_mass": 21260.0, "monoisotopic_mass": 21260.0 }, "refseq": { "ac": "XP_021324603", "name": "urokinase plasminogen activator surface receptor-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324603" }, "gene_names": [ { "name": "ly6m5", "type": "recommended", "evidence": [ { "id": "A0A8M9PCV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCV3" } ] }, { "name": "ly6m5", "type": "synonym", "evidence": [ { "id": "XP_021324603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324603" } ] } ], "protein_names": [ { "name": "Urokinase plasminogen activator surface receptor-like", "type": "synonym", "evidence": [ { "id": "A0A8M9PCV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCV3/entry#names_and_taxonomy" } ] }, { "name": "urokinase plasminogen activator surface receptor-like", "type": "synonym", "evidence": [ { "id": "XP_021324603", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324603" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324603", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324603" } ] } ], "disease": [ { "disease_id": "DOID:1824", "recommended_name": { "id": "DOID:1824", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1824", "name": "status epilepticus", "description": "" }, "synonyms": [ { "id": "DOID:1824", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1824", "name": "Grand mal status", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ] }, { "disease_id": "DOID:3083", "recommended_name": { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive pulmonary disease", "description": "An obstructive lung disease that is a chronic and progressive disorder of small airways in the lungs and that is characterized by irreversible airflow obstruction, typically identified by reductions in quantitative spirometric indices, induced forced expiratory volume at 1 second (FEV1) and the ratio of FEV1 to forced vital capacity (less than 0.7 is diagnostic of COPD). Lung volume is increased and pulmonary hypertension may occur. The pathologic changes result in the disruption of the airflow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough and chest tightness. COPD is a consequence (an end result) of chronic bronchitis, emphysema or both." }, "synonyms": [ { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "COLD", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "COPD", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive airway disease", "description": "" }, { "id": "DOID:3083", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3083", "name": "chronic obstructive lung disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease", "description": "A chronic and progressive lung disorder characterized by the loss of elasticity of the bronchial tree and the air sacs, destruction of the air sacs wall, thickening of the bronchial wall, and mucous accumulation in the bronchial tree. The pathologic changes result in the disruption of the air flow in the bronchial airways. Signs and symptoms include shortness of breath, wheezing, productive cough, and chest tightness. The two main types of chronic obstructive pulmonary disease are chronic obstructive bronchitis and emphysema." }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COLD", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COPD", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "COPD, chronic obstructive pulmonary disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive airways disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive lung disease", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease (COPD)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "chronic obstructive pulmonary disease, (COPD)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "cold", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "cold (chronic obstructive lung disease)", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "disease (COPD), chronic obstructive", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "obstructive lung disease, chronic", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "obstructive pulmonary disease (COPD), chronic", "description": "" }, { "id": "MONDO:0005002", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005002", "name": "pulmonary disease (COPD), chronic obstructive", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3083", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3083" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCV3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCV3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ly6m5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCV3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131127-265", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-265", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PCV3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PCV3", "database": "AlphaFoldDB", "categories": [] }, { "id": "101882984", "url": "https://www.ncbi.nlm.nih.gov/gene/101882984", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035076", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035076", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050918", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050918", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101882984", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882984", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PCV3", "url": "https://www.orthodb.org/?gene=A0A8M9PCV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20914", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20914", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20914:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20914:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00021", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00021", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021324603", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324603", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PCV3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131127-265", "url": "https://zfin.org/ZDB-GENE-131127-265", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDLQVSVLLLFVTFTSGHSLSCYQCDDLMGLCRFQTERTCPSGLSKCESVTVVRQLGTTSFTVKAKACSADCASGTMNFGISQMSSTCCNSDQCNKKDAPVPSTGTPNGKMCYYCDENNCFNALSYSGREDHCITATGTFAGESVIVKGCASKSICDGKKMGAFKNFSCCSGNLCNGAKSVTQSFLFLCFPLIAFILML", "length": 199, "header": "tr|A0A8M9PCV3-1|A0A8M9PCV3_DANRE Isoform 1 of Urokinase plasminogen activator surface receptor-like OS=Danio rerio OX=7955 GN=ly6m5 PE=4 SV=1 CANONICAL=A0A8M9PCV3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PCV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCV3/entry#A0A8M9PCV3-1", "sequence": { "sequence": "MDLQVSVLLLFVTFTSGHSLSCYQCDDLMGLCRFQTERTCPSGLSKCESVTVVRQLGTTSFTVKAKACSADCASGTMNFGISQMSSTCCNSDQCNKKDAPVPSTGTPNGKMCYYCDENNCFNALSYSGREDHCITATGTFAGESVIVKGCASKSICDGKKMGAFKNFSCCSGNLCNGAKSVTQSFLFLCFPLIAFILML", "length": 199, "header": "tr|A0A8M9PCV3-1|A0A8M9PCV3_DANRE Isoform 1 of Urokinase plasminogen activator surface receptor-like OS=Danio rerio OX=7955 GN=ly6m5 PE=4 SV=1 CANONICAL=A0A8M9PCV3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101882984", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882984", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB13A3T4-1", "protein_name": "Uncharacterized protein LOC566752 precursor", "gene_name": "si:dkey-102g19.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHQQVILLSVLLTGGFSLNCYDCQNSEDSGRCGNVTCDRQHTKCASERIESYFGVTKVDLVSKRCVMPVQCVSWSISTACGRTDHSVQCCDNDLCNDQKAPVLSPPTPNGKKCFACDWEDCSKTVNCQRNEDYCFSAYSGAETLKGCGTKSVCDEPEIFKRELNKIITCCSGNLCNGAESFLQSFMFLCFSLITVILVH", "length": 199 }, "evidence": [ { "id": "RGD:1585065", "url": "https://alliancegenome.org/gene/RGD:1585065#orthology", "database": "AGR" }, { "id": "HGNC:44206", "url": "https://alliancegenome.org/gene/HGNC:44206#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NC86-1", "protein_name": "phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein", "gene_name": "PINLYP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLSRRPETFLLAFVLLCTLLGLGCPLHCEICTAAGSRCHGQMKTCSSDKDTCVLLVGKATSKGKELVHTYKGCIRSQDCYSGVISTTMGPKDHMVTSSFCCQSDGCNSAFLSVPLTNLTENGLMCPACTASFRDKCMGPMTHCTGKENHCVSLSGHVQAGIFKPRFAMRGCATESMCFTKPGAEVPTGTNVLFLHHIECTHSP", "length": 204 }, "evidence": [ { "id": "RGD:1565787", "url": "https://alliancegenome.org/gene/RGD:1565787#orthology", "database": "AGR" }, { "id": "HGNC:44206", "url": "https://alliancegenome.org/gene/HGNC:44206#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131127-265", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-265#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZFP5-1", "protein_name": "LY6/PLAUR domain containing 8 like 2", "gene_name": "Lypd8l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGWSSILKSLFTVFVFSILVVGSVEGYTCLQATCGNGNCFEPLTTCDTTVGCFNQIQKLEAPLPGSNQVLEQKGCNTDTKTCGLEFSATLGSQQTFKYKNQCCTTDKCNKENIALSRSSEINGVECTACYSEQNKTCSTITTLKCTGAERKCLEVTGTDQSSNLIFYGKGCATENTCSLDMNVFNNIKIKTLCIPATNGSPTFKSIASLPIVLLLLKILL", "length": 220 }, "evidence": [ { "id": "RGD:1585065", "url": "https://alliancegenome.org/gene/RGD:1585065#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131127-265", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-265#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A499-1", "protein_name": "Phospholipase A2 inhibitor and Ly6/Plaur domain containing", "gene_name": "Pinlyp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILFRRHRTFLLALTLLCTLLGLGCPLSCEVCKGSGHTCSGKMKTCEAGKDACVVLVGESSTKGRKSVNTFKACMKFKDCYSGFVSTTMSPNDYMVSNAHCCQSDGCNSGSVPPPPNNRTENGLMCPSCIAPFQETCPGTQAARCVGRETHCIYFAGNVQAGIINTKFATRGCATESACYTKAGAEVPSASYLYFLRRADCLPAPYPPGRGE", "length": 212 }, "evidence": [ { "id": "RGD:1565787", "url": "https://alliancegenome.org/gene/RGD:1565787#orthology", "database": "AGR" }, { "id": "HGNC:44206", "url": "https://alliancegenome.org/gene/HGNC:44206#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131127-265", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-265#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P35456-1", "protein_name": "Urokinase plasminogen activator surface receptor", "gene_name": "Plaur", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLPRRLLLLLLLATTCVPASQGLQCMQCESNQSCLVEECALGQDLCRTTVLREWQDDRELEVVTRGCAHSEKTNRTMSYRMGSMIISLTETVCATNLCNRPRPGARGRAFPQGRYLECASCTSLDQSCERGREQSLQCRYPTEHCIEVVTLQSTERSLKDEDYTRGCGSLPGCPGTAGFHSNQTFHFLKCCNYTHCNGGPVLDLQSFPPNGFQCYSCEGNNTLGCSSEEASLINCRGPMNQCLVATGLDVLGNRSYTVRGCATASWCQGSHVADSFPTHLNVSVSCCHGSGCNSPTGGAPRPGPAQLSLIASLLLTLGLWGVLLWT", "length": 327 }, "evidence": [ { "id": "RGD:620597", "url": "https://alliancegenome.org/gene/RGD:620597#orthology", "database": "AGR" }, { "id": "MGI:97612", "url": "https://alliancegenome.org/gene/MGI:97612#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131127-265", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-265#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P49616-1", "protein_name": "Urokinase plasminogen activator surface receptor", "gene_name": "Plaur", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLLRRRLLLLVVVVTTCVPASQGLRCIQCESNQDCLVEECALGQDLCRTTVLREWEDAEELEVVTRGCAHKEKTNRTMSYRMGSVIVSLTETVCATNLCNRPRPGARGRPFPRGRYLECASCTSLDQSCERGREQSLQCRYPTEHCIEVVTLQSTERSVKDEPYTKGCGSLPGCPGTAGFHSNQTFHFLKCCNFTQCNGGPVLDLQSLPPNGFQCYSCEGNSTFGCSYEETSLIDCRGPMNQCLEATGLDVLGNRSYTVRGCATASWCQGSHVADSFQTHVNLSISCCNGSGCNRPTGGAPGPGPAHLILIASLLLTLRLWGIPLWT", "length": 328 }, "evidence": [ { "id": "RGD:620597", "url": "https://alliancegenome.org/gene/RGD:620597#orthology", "database": "AGR" }, { "id": "MGI:97612", "url": "https://alliancegenome.org/gene/MGI:97612#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131127-265", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-265#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q03405-1", "protein_name": "Urokinase plasminogen activator surface receptor", "gene_name": "PLAUR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEELELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISCGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNGFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGPMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDVQYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLWT", "length": 335 }, "evidence": [ { "id": "RGD:620597", "url": "https://alliancegenome.org/gene/RGD:620597#orthology", "database": "AGR" }, { "id": "MGI:97612", "url": "https://alliancegenome.org/gene/MGI:97612#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CQD7-1", "protein_name": "phospholipase A2 inhibitor and Ly6/PLAUR domain-containing protein", "gene_name": "Pinlyp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MILFRRHRTFLLAFTLLCTLLGLGCPLTCEVCKGSGHTCSGKMKTCEDGKDACVVLVSESSTKGRKSVNTFKACMKYKDCYSGFVSTTMTPSDYMVSNAHCCQSDGCNSGSVPPPLNNRTENGLMCPSCIAPFQETCPGTQAARCVGRETHCIYFAGNVQAGIIHTKFATRGCATESACHTKAGAEVPSAFYLYFLRRADCLPAPYPPGRGE", "length": 212 }, "evidence": [ { "id": "RGD:1565787", "url": "https://alliancegenome.org/gene/RGD:1565787#orthology", "database": "AGR" }, { "id": "HGNC:44206", "url": "https://alliancegenome.org/gene/HGNC:44206#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCV3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCV3" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCV3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCV3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PCV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCV3" }, { "id": "SM00134", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00134" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UPAR/Ly6", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 108, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PCW4-1", "uniprot_ac": "A0A8M9PCW4", "uniprot_id": "A0A8M9PCW4_DANRE", "mass": { "chemical_mass": 282065.0, "monoisotopic_mass": 282065.0 }, "refseq": { "ac": "XP_073791698", "name": "zinc finger protein 462 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073791698" }, "gene_names": [ { "name": "znf462", "type": "recommended", "evidence": [ { "id": "A0A8M9PCW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4" } ] }, { "name": "znf462", "type": "synonym", "evidence": [ { "id": "XP_073791698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073791698" } ] } ], "protein_names": [ { "name": "Zinc finger protein 462 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PCW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 462 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_073791698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073791698" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073791698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073791698" } ] } ], "disease": [ { "disease_id": "DOID:14320", "recommended_name": { "id": "DOID:14320", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14320", "name": "generalized anxiety disorder", "description": "An anxiety disorder that is characterized by long-lasting anxiety that is not focused on any one object or situation." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "14320", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14320" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCW4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "znf462", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-6997", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6997", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "335057", "url": "https://www.ncbi.nlm.nih.gov/gene/335057", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050688", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050688", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057830", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057830", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057831", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057831", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059059", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059059", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:335057", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:335057", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PCW4", "url": "https://www.orthodb.org/?gene=A0A8M9PCW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24403:SF58", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24403:SF58", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23075", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23075", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23077", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23077", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23223", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23223", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23224", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23224", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23225", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23225", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073791698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073791698", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PCW4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PII5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PII5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PII5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PII5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-6997", "url": "https://zfin.org/ZDB-GENE-030131-6997", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEGLQCDGCDFRAESYEELKAHIRDIHTAFLQPAEVQDGDGDETPKRSRSTSLSQTEDEEDSTNQERDPLKEETGVSSFNKDFGHFSGSKQAKHNPSAKPSNKTTAPFFQCKFCVRYFRSSSLLSEHTRKVHGEAGDERSLKTPKQASSSMHNAVGTVFSCQYCTYKSPHRARILKHQKVHHKEAPTGLSAPPADAEVLDLDSDVSSIEELSEDSPGDVERHVLESMIKPQSKGGFNCEWCGFQTSQRQQLADHMMKKHRNMVKIMVSLQQPKVQDGSAGSSKSDSASSRRSTPTSNLNLNDIAGNESSSANASSVKGSGNASLKASSGISSFQYSQLTSKIPNSTGSSILSERSTFAMSDISRSGMDLDASVLNDSRSSSDDELCDMDDANNTESAKDSAKLLLSEEDNDLLETKGVPFRRHMNRFQCPFCSFLTMHRRSISRHIENIHLSGKATVYKCDSCPFLCTNPLKLDAHKQCHSGSSEWDTMDLTSGSPEGQAECSEPVNGGNGSSKINGKKSSGGEEQQGPHRCSLCNFSTITLKGLRVHQQHKHSYCDGTQVPGQEGLSTEQQDSESESCGSTSFVQKTQTSILGFSTKKHLIGKTARKSINDLPLDLSPVKKRTRIDEIANNLQSKISQSQQHEDVINLEEMDDDVEENGNHIDAEASKDRDSSNARSQHYMFNTQHLHGRNSGGLPTERGVGKRKRSLQSKLSSRNLPVQLTISDDEDSYNGSLESKHAQDQSSQDGREMHQENVEYTAEPGNLFYCKHCEYQNKSARSVSTHYQRMHPYIKFSFRYILDPEDQSAVFRCLECFIEYNNFNDLHQHYMTHHPEASNVLNFNQPDLVYMCRFCSYTSPNVRSLMPHYQRMHPSVKINNAMIFSSYMVDQPHKGATESQTLREILNSGPKSFSSTSSGSRSSSSPALKSISKTPEANAEVETLRESLGGNVVVYDCDVCSFSSPNMHSVLVHYQKKHPEQKASYFRIQKTMRVISVERAQMASNSTYSLTSTPKSSNPILPVPLDEDVYYCKHCVYNNRSVVGVLVHYQKRHPEIKVTAKYIKQAPPTPGLLKLMDELQIAPPKQFLKQFSNNGIEGSGNSNTKGASDKGEPEMLFFCQHCDYGNRTVKGVLIHYQKKHRDVKANADLVRRHTAVVQSQRERAQMIQSGSSTSTSTVATEAEKSRSLRSLKCRHCPYTSPYVYALKKHLKKDHPTVKATAMTILHWAYQDGVLEAGYHCEWCIYSHAEPSGLLMHYQRRHPEHNVDYTYMASKLWAGPDSSTSRQAGNSETKHYQCRDCAFEACSIWDITNHYQAVHPWAIKGDESVLIDIIKGNKAPDKQLPQQTKAHASMSSPFNSHHQEDVAVEMNRPPLDRQPNLSLSATSSISNNPYQCTVCLSEYNSLHGLLTHYGKKHPGMKVKAADFAQEADINPSSVYKCRHCPYVNSRIHGVLTHYQKRHPSIKVTAEDFVDDVEQVNEVSSENEERSKTQRQGYGAYRCKMCPYTHGTLEKLKIHYEKYHNQPAAHMFKASNIQSPTGRDDLVAECSTSSQPEVPEVCDYNVPISEVAKSDKHAVFKCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNVFKCALCSYTNPIRKGLAAHYQKRHDIDAYYTHCLAASKTVTEKPNKVMLPLASEADSSGMSEELRQAVDRRKCSLCSFQAFSRKSIVSHYIKRHPGVFPKKQAASKLGRYFTMIYPKDAEESPIVENVEIVEVKDEVEPEGEVDWLPFKCLKCFKLSFNAEELLVMHYNDCHDKELKRDFVTVPSPVEDGTELYQCTHCEIKFLTLPELSIHLTNHNEDFQKKAMRMERRKQLQSKQKTVEPPEAKPEIKVDGTPGKTPVGYKCNFCVEIHPSLRSICNHLRKHVQYREAKDAHLKQESAEAPVTPAGVSNGDLLSGPAEAPAGVSVSEPEPPDGLEPLEKSRLPPGHPCGLCDRMFMSMQGLRSHERSHSAVTLLNRSDKHNCQYCQFSSPFRHNLDRHVQSHHGHQKPFRCKLCPFKSSYMSRLKSHMNKTHAGERPYKCVSCVFSAVSISQLKEHSLQEHGETLTLHRLKTAAPRNTQPADEDEEEEEEEEEKPERSESAYLEPADVQQQISHFQLSSRVQSDVSSSPSDTALPQARPESILTCEFCEFSSGYMQSLRRHYRDRHGGKKLFKCKDCTFFTCNKSTFTLHVEGGHSSSSTTGAAEEPQKELRCPFCLYHTKHKSSMIDHIVLHREERVVPLEISRSKLSRHLEGLVFRCHKCTFTCSSEQNLQQHIQKHEELKPYQCQLCYYDSKLLHELETHLQDQHKVIRNYELVGRVNLDQLDLLKDKMKDMSSSEEEEREETEPVEEEAEEEEELPMEEEEEEKLPEDRQEETSCQTEDADAADVASPESPGSVAVKRFPCEFCGRTFTLSTEWERHVLRHGMTVNGSKTEGSPVPSSALPLIGPLAVIDRELDQSGDTDDQSDQSKCQNPNEEEKKTLETKNDP", "length": 2503, "header": "tr|A0A8M9PCW4-1|A0A8M9PCW4_DANRE Isoform 1 of Zinc finger protein 462 isoform X1 OS=Danio rerio OX=7955 GN=znf462 PE=1 SV=2 CANONICAL=A0A8M9PCW4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PCW4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4/entry#A0A8M9PCW4-1", "sequence": { "sequence": "MEGLQCDGCDFRAESYEELKAHIRDIHTAFLQPAEVQDGDGDETPKRSRSTSLSQTEDEEDSTNQERDPLKEETGVSSFNKDFGHFSGSKQAKHNPSAKPSNKTTAPFFQCKFCVRYFRSSSLLSEHTRKVHGEAGDERSLKTPKQASSSMHNAVGTVFSCQYCTYKSPHRARILKHQKVHHKEAPTGLSAPPADAEVLDLDSDVSSIEELSEDSPGDVERHVLESMIKPQSKGGFNCEWCGFQTSQRQQLADHMMKKHRNMVKIMVSLQQPKVQDGSAGSSKSDSASSRRSTPTSNLNLNDIAGNESSSANASSVKGSGNASLKASSGISSFQYSQLTSKIPNSTGSSILSERSTFAMSDISRSGMDLDASVLNDSRSSSDDELCDMDDANNTESAKDSAKLLLSEEDNDLLETKGVPFRRHMNRFQCPFCSFLTMHRRSISRHIENIHLSGKATVYKCDSCPFLCTNPLKLDAHKQCHSGSSEWDTMDLTSGSPEGQAECSEPVNGGNGSSKINGKKSSGGEEQQGPHRCSLCNFSTITLKGLRVHQQHKHSYCDGTQVPGQEGLSTEQQDSESESCGSTSFVQKTQTSILGFSTKKHLIGKTARKSINDLPLDLSPVKKRTRIDEIANNLQSKISQSQQHEDVINLEEMDDDVEENGNHIDAEASKDRDSSNARSQHYMFNTQHLHGRNSGGLPTERGVGKRKRSLQSKLSSRNLPVQLTISDDEDSYNGSLESKHAQDQSSQDGREMHQENVEYTAEPGNLFYCKHCEYQNKSARSVSTHYQRMHPYIKFSFRYILDPEDQSAVFRCLECFIEYNNFNDLHQHYMTHHPEASNVLNFNQPDLVYMCRFCSYTSPNVRSLMPHYQRMHPSVKINNAMIFSSYMVDQPHKGATESQTLREILNSGPKSFSSTSSGSRSSSSPALKSISKTPEANAEVETLRESLGGNVVVYDCDVCSFSSPNMHSVLVHYQKKHPEQKASYFRIQKTMRVISVERAQMASNSTYSLTSTPKSSNPILPVPLDEDVYYCKHCVYNNRSVVGVLVHYQKRHPEIKVTAKYIKQAPPTPGLLKLMDELQIAPPKQFLKQFSNNGIEGSGNSNTKGASDKGEPEMLFFCQHCDYGNRTVKGVLIHYQKKHRDVKANADLVRRHTAVVQSQRERAQMIQSGSSTSTSTVATEAEKSRSLRSLKCRHCPYTSPYVYALKKHLKKDHPTVKATAMTILHWAYQDGVLEAGYHCEWCIYSHAEPSGLLMHYQRRHPEHNVDYTYMASKLWAGPDSSTSRQAGNSETKHYQCRDCAFEACSIWDITNHYQAVHPWAIKGDESVLIDIIKGNKAPDKQLPQQTKAHASMSSPFNSHHQEDVAVEMNRPPLDRQPNLSLSATSSISNNPYQCTVCLSEYNSLHGLLTHYGKKHPGMKVKAADFAQEADINPSSVYKCRHCPYVNSRIHGVLTHYQKRHPSIKVTAEDFVDDVEQVNEVSSENEERSKTQRQGYGAYRCKMCPYTHGTLEKLKIHYEKYHNQPAAHMFKASNIQSPTGRDDLVAECSTSSQPEVPEVCDYNVPISEVAKSDKHAVFKCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNVFKCALCSYTNPIRKGLAAHYQKRHDIDAYYTHCLAASKTVTEKPNKVMLPLASEADSSGMSEELRQAVDRRKCSLCSFQAFSRKSIVSHYIKRHPGVFPKKQAASKLGRYFTMIYPKDAEESPIVENVEIVEVKDEVEPEGEVDWLPFKCLKCFKLSFNAEELLVMHYNDCHDKELKRDFVTVPSPVEDGTELYQCTHCEIKFLTLPELSIHLTNHNEDFQKKAMRMERRKQLQSKQKTVEPPEAKPEIKVDGTPGKTPVGYKCNFCVEIHPSLRSICNHLRKHVQYREAKDAHLKQESAEAPVTPAGVSNGDLLSGPAEAPAGVSVSEPEPPDGLEPLEKSRLPPGHPCGLCDRMFMSMQGLRSHERSHSAVTLLNRSDKHNCQYCQFSSPFRHNLDRHVQSHHGHQKPFRCKLCPFKSSYMSRLKSHMNKTHAGERPYKCVSCVFSAVSISQLKEHSLQEHGETLTLHRLKTAAPRNTQPADEDEEEEEEEEEKPERSESAYLEPADVQQQISHFQLSSRVQSDVSSSPSDTALPQARPESILTCEFCEFSSGYMQSLRRHYRDRHGGKKLFKCKDCTFFTCNKSTFTLHVEGGHSSSSTTGAAEEPQKELRCPFCLYHTKHKSSMIDHIVLHREERVVPLEISRSKLSRHLEGLVFRCHKCTFTCSSEQNLQQHIQKHEELKPYQCQLCYYDSKLLHELETHLQDQHKVIRNYELVGRVNLDQLDLLKDKMKDMSSSEEEEREETEPVEEEAEEEEELPMEEEEEEKLPEDRQEETSCQTEDADAADVASPESPGSVAVKRFPCEFCGRTFTLSTEWERHVLRHGMTVNGSKTEGSPVPSSALPLIGPLAVIDRELDQSGDTDDQSDQSKCQNPNEEEKKTLETKNDP", "length": 2503, "header": "tr|A0A8M9PCW4-1|A0A8M9PCW4_DANRE Isoform 1 of Zinc finger protein 462 isoform X1 OS=Danio rerio OX=7955 GN=znf462 PE=1 SV=2 CANONICAL=A0A8M9PCW4-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PII5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4/entry#A0A8M9PII5-1", "sequence": { "sequence": "MEGLQCDGCDFRAESYEELKAHIRDIHTAFLQPAEVQDGDGDETPKRSRSTSLSQTEDEEDSTNQERDPLKEETGVSSFNKDFGHFSGSKQAKHNPSAKPSNKTTAPFFQCKFCVRYFRSSSLLSEHTRKVHGEAGDERSLKTPKQASSSMHNAVGTVFSCQYCTYKSPHRARILKHQKVHHKEAPTGLSAPPADAEVLDLDSDVSSIEELSEDSPGDVERHVLESMIKPQSKGGFNCEWCGFQTSQRQQLADHMMKKHRNMVKIMVSLQQPKVQDGSAGSSKSDSASSRRSTPTSNLNLNDIAGNESSSANASSVKGSGNASLKASSGISSFQYSQLTSKIPNSTGSSILSERSTFAMSDISRSGMDLDASVLNDSRSSSDDELCDMDDANNTESAKDSAKLLLSEEDNDLLETKGVPFRRHMNRFQCPFCSFLTMHRRSISRHIENIHLSGKATVYKCDSCPFLCTNPLKLDAHKQCHSGSSEWDTMDLTSGSPEGQAECSEPVNGGNGSSKINGKKSSGGEEQQGPHRCSLCNFSTITLKGLRVHQQHKHSYCDGTQVPGQEGLSTEQQDSESESCGSTSFVQKTQTSILGFSTKKHLIGKTARKSINDLPLDLSPVKKRTRIDEIANNLQSKISQSQQHEDVINLEEMDDDVEENGNHIDAEASKDRDSSNARSQHYMFNTQHLHGRNSGGLPTERGVGKRKRSLQSKLSSRNLPVQLTISDDEDSYNGSLESKHAQDQSSQDGREMHQENVEYTAEPGNLFYCKHCEYQNKSARSVSTHYQRMHPYIKFSFRYILDPEDQSAVFRCLECFIEYNNFNDLHQHYMTHHPEASNVLNFNQPDLVYMCRFCSYTSPNVRSLMPHYQRMHPSVKINNAMIFSSYMVDQPHKGATESQTLREILNSGPKSFSSTSSGSRSSSSPALKSISKTPEANAEVETLRESLGGNVVVYDCDVCSFSSPNMHSVLVHYQKKHPEQKASYFRIQKTMRVISVERAQMASNSTYSLTSTPKSSNPILPVPLDEDVYYCKHCVYNNRSVVGVLVHYQKRHPEIKVTAKYIKQAPPTPGLLKLMDELQIAPPKQFLKQFSNNGIEGSGNSNTKGASDKGEPEMLFFCQHCDYGNRTVKGVLIHYQKKHRDVKANADLVRRHTAVVQSQRERAQMIQSGSSTSTSTVATEAEKSRSLRSLKCRHCPYTSPYVYALKKHLKKDHPTVKATAMTILHWAYQDGVLEAGYHCEWCIYSHAEPSGLLMHYQRRHPEHNVDYTYMASKLWAGPDSSTSRQAGNSETKHYQCRDCAFEACSIWDITNHYQAVHPWAIKGDESVLIDIIKGNKAPDKQLPQQTKAHASMSSPFNSHHQEDVAVEMNRPPLDRQPNLSLSATSSISNNPYQCTVCLSEYNSLHGLLTHYGKKHPGMKVKAADFAQEADINPSSVYKCRHCPYVNSRIHGVLTHYQKRHPSIKVTAEDFVDDVEQVNEVSSENEERSKTQRQGYGAYRCKMCPYTHGTLEKLKIHYEKYHNQPAAHMFKASNIQSPTGRDDLVAECSTSSQPEVPEVCDYNVPISEVAKSDKHAVFKCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNVFKCALCSYTNPIRKGLAAHYQKRHDIDAYYTHCLAASKTVTEKPNKVMLPLASEADSSGMSEELRQAVDRRKCSLCSFQAFSRKSIVSHYIKRHPGVFPKKQAASKLGRYFTMIYPKDAEESPIVENVEIVEVKDEVEPEGEVDWLPFKCLKCFKLSFNAEELLVMHYNDCHDKELKRDFVTVPSPVEDGTELYQCTHCEIKFLTLPELSIHLTNHNEDFQKKAMRMERRKQLQSKQKTVEPPEAKPEIKVDGTPGKTPVGYKCNFCVEIHPSLRSICNHLRKHVQYREAKDAHLKESAEAPVTPAGVSNGDLLSGPAEAPAGVSVSEPEPPDGLEPLEKSRLPPGHPCGLCDRMFMSMQGLRSHERSHSAVTLLNRSDKHNCQYCQFSSPFRHNLDRHVQSHHGHQKPFRCKLCPFKSSYMSRLKSHMNKTHAGERPYKCVSCVFSAVSISQLKEHSLQEHGETLTLHRLKTAAPRNTQPADEDEEEEEEEEEKPERSESAYLEPADVQQQISHFQLSSRVQSDVSSSPSDTALPQARPESILTCEFCEFSSGYMQSLRRHYRDRHGGKKLFKCKDCTFFTCNKSTFTLHVEGGHSSSSTTGAAEEPQKELRCPFCLYHTKHKSSMIDHIVLHREERVVPLEISRSKLSRHLEGLVFRCHKCTFTCSSEQNLQQHIQKHEELKPYQCQLCYYDSKLLHELETHLQDQHKVIRNYELVGRVNLDQLDLLKDKMKDMSSSEEEEREETEPVEEEAEEEEELPMEEEEEEKLPEDRQEETSCQTEDADAADVASPESPGSVAVKRFPCEFCGRTFTLSTEWERHVLRHGMTVNGSKTEGSPVPSSALPLIGPLAVIDRELDQSGDTDDQSDQSKCQNPNEEEKKTLETKNDP", "length": 2502, "header": "tr|A0A8M9PII5-1|A0A8M9PII5_DANRE Computationally mapped isoform of Zinc finger protein 462 isoform X2 OS=Danio rerio OX=7955 GN=znf462 PE=1 SV=2 CANONICAL=A0A8M9PCW4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1067, "start_aa": "Thr", "end_pos": 1067, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1067", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:335057", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:335057", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LIX2-1", "protein_name": "Zinc finger protein 462", "gene_name": "Zfp462", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVLQCDGCDFRAPSYEDLKAHIQDVHTAFLQPTDVAEDNDDEPLSGSVNAGNQTEVEFSSIKDEFVIAEDLSGQSATALGSGSYYGHSPGYYGQHITPNPKPTNKFFQCKFCVRYFRSKNLLIEHTRKVHGAQAEESPTGPPVPGSLNYNIMMHEGFGKVFSCQFCTYKSPRRARIIKHQKMYHKNSLKESAAPPPAPAPLSDPVVPPVSLQDPCKELPAEVVERSILESMVKPLTKSRGNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSNIRQQQEGTNVSEVQNNNEPSPTSNSTYLSMNAASREMPNTNVSNFRGSVGNSIMRPNSSSTSKFSPMSYPQMKPKSPHNSGLVNLTERSRYGMSDMTNSSADLDTNSMLNDSSSDEDLNEVDSENGLSVMDHQASGLSAEQLMGSDGNKLLETKGIPFRRFMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTSDWDTVNSQSESLSSSLNEGMLSYESPSINGRKSGVMLDPLQQQQPPQPPPPLPPPPPPPSQPVQQPPPPQLQSPHQVPPQPQPPPPTQQPQPPTQVPPLHPYKCTMCSYSTMTLKGLRVHQQHKHSFCDNLPKFEGQPSSLPLENETDSHPSSSNTVKKSQTSILGLSSKNNFVAKASRKLANDFPLDLSPVKKRTRIDEIASNLQSKINQTKLQEDAIINVEDDEEEEDDNEVEIEVELDREEEPTEPIMDVPTAFSAQQIWARDTSESQKEANYRSITHDYTATNGAEIELTLSEDEEDYYGSSTSIKDHQVSNAALLNTQPPIYGTEHSNENTDFGDSGRLYYCKHCDFNNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFEDLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFSSYVVEQQEGLNAESQTLREILNSAPKSMATSTPVARGGGMPATFNKNTSPKTFTPECENQKDPSVNTVVVYDCDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRMVSVDRGSALAQLSFEVGAPMSPKMSNMGSPPPPQPPPPDLSIELYYCKHCSYSNRSVVGVLVHYQKRHPEIKVTAKYIRQAPPTAAMMRGAEGLQDSPRPPAPMQLNRSSSERDCPPVETEMFFCQHCDYGNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRNQKPASCVLLPASGMERDKTKLRALKCRQCSYTSPYFYALRKHIKKDHPALKATVTSIMRWAFLDGLIEAGYHCEWCIYSHMEPSGLLLHYQRRHPEHYVDYTYMATKLWAGPDPSSPTLTMSAEAKTYRCRDCAFEAVSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDGVDKALLAPEELIGAVNCENSLPNPLPEQEAECPEDARLSPEKSIHLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDVDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPAIKVTAEDFVHDVEQSADITQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSPSPPKLPVSLEPEITTEVSPSQVSMTEEEVGEDPMSTAHFSTSHLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKPPLMEEEGRSGFERPEVEGEAQDIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFVILGSGPRFQNSTFQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEAPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGSVPAVSAAVKQEAEDPSHLFLDGFEAARDASGTLVGRVDGGHCLLDGMLEDETRPGGYHCSQCDRVLMSMQGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHAHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPPSGTAAGTEQKAEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELRPYKCQLCYYETKHTEELDTHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKDDEMSSKTEDRELMRFSDRGAGVNTEKRFPCEFCGRAFSQGSEWERHVLRHGMALHDTDQVSRDEIHTKEMVEDSMQLPSIEAKEDDEPIGIDFPLKSETVTICVVAADKSLLENAEAKTE", "length": 2565 }, "evidence": [ { "id": "RGD:1562123", "url": "https://alliancegenome.org/gene/RGD:1562123#orthology", "database": "AGR" }, { "id": "MGI:107690", "url": "https://alliancegenome.org/gene/MGI:107690#orthology", "database": "AGR" }, { "id": "HGNC:21684", "url": "https://alliancegenome.org/gene/HGNC:21684#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6997", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6997#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B1AWL2-1", "protein_name": "Zinc finger protein 462", "gene_name": "Znf462", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLQCDGCDFRAPSYEDLKAHIQDVHTAFLQPTDVAEDNDDEPLSGSMNASNQTEVEFSSIKDEFVIAEDLPGQSATALGSGGYYGHSPGYYGQHITPNPKPTNKFFQCKFCVRYFRSKNLLIEHTRKVHGAQAEESPTGPPVPGSLNYNIMMHEGFGKVFSCQFCTYKSPRRARIIKHQKMYHKNSLKESTAPPPAPAPLPDPLVPPVSLQDPCKELPAEVVERSILESMVKPLTKSRGNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSIRQQEGPNVSEAQNDNEPSPTSNSTYLSMNAASREMPNANVSNFRGSMGNSIMRPNSSSTSKFSSSMSYPQMKPKSPHNSGLVNLTERSRYGMSDMTNSSADLDTNSMLNDSSSDEDLNEVDSENGLSVLDHQASGLSAEQLMGSDGNKLLETKGIPFRRFMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTSDWDTVNSQSESLSSSLNEGMVSYESSSINGRKSGVMLDPLQQQQPPQPPPPLPPPPPPPSQPLPQPPPPPLQSPHQVPPPTQQPQPPTQAPPLHPYKCTMCSYSTMTLKGLRVHQQHKHSFCDNLPKFEGQPSSLPLENETDSHPSSSNTVKKSQTSILGLSSKNNFVAKANRKLASDFPLDLSPVKKRTRIDEIASNLQSKINQTKLQEDAIINVEDDEEEEDDNEVEIEVELDREEEATDPIMEVPTAFSAQQIWARDASEAQKEPNYRSITHDYTATNGAEIELTLSEDEEDYYGSSASMKDQVSNAALLNTQPAIYGTEPSNENTDFGDSGRLYYCKHCDFNNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFEDLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFSSYVVEQQEGLNAESQTLREILNSAPKSMATSTPVARGGGLPATFNKNTPPKTFTPECESQKDPSVNTVVVYDCDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRMVSVDRGSALSQLSFEVGAPMSPKMSNMGSPPPPQPPPPDLSIELYYCKHCSYSNRSVVGVLVHYQKRHPEIKVTAKYIRQAPPTAAMMRGAEGLQDSPRPPAPLQLNSSERDCPPVETEMFFCQHCDYGNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRNQKPASCVLLPASGMERDKTKLRALKCRQCSYTSPYFYALRKHIKKDHPALKATVTSIMRWAFLDGLIEAGYHCEWCIYSHMEPSGLLLHYQRRHPEHYVDYTYMATKLWAGPDPSSPTLTMSAEAKTYRCRDCVFEAVSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDGVDKALLAPEELIGPVNCENSIPNPLPEQEAECPEDARLSPEKSIHLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPAIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSPPPPKLPVSLEPEITTEVSPSQVSVTEEEVGEDPMSTAHFSTSHLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKPPLMEEEERSSFERAEVEGEAQDIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFVILGSGPRFQNSTFQCKHCDSKLQSIAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGSVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHAHPSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNKSRVSPVPPSGTAAGTEQKAEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDTHLRDEHKVSRNFELVGRVNLDQLEQMKEKIESSSSEDEDKDDEMSSKAEDRELMRFADRGPGVNTEKRFPCEFCGRAFSQGSEWERHVLRHGMSLHDTNQVSRNEIHTKEMVEESMQLPSIEAKEDDEPIGIDFPLKSETVTICVVAADKSLLEDAEAKNE", "length": 2495 }, "evidence": [ { "id": "RGD:1562123", "url": "https://alliancegenome.org/gene/RGD:1562123#orthology", "database": "AGR" }, { "id": "MGI:107690", "url": "https://alliancegenome.org/gene/MGI:107690#orthology", "database": "AGR" }, { "id": "HGNC:21684", "url": "https://alliancegenome.org/gene/HGNC:21684#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6997", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6997#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96JM2-1", "protein_name": "Zinc finger protein 462", "gene_name": "ZNF462", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVLQCDGCDFRAPSYEDLKAHIQDVHTAFLQPTDVAEDNVNELRCGSVNASNQTEVEFSSIKDEFAIAEDLSGQNATSLGTGGYYGHSPGYYGQHIAANPKPTNKFFQCKFCVRYFRSKNLLIEHTRKVHGAQAEGSSSGPPVPGSLNYNIMMHEGFGKVFSCQFCTYKSPRRARIIKHQKMYHKNNLKETTAPPPAPAPMPDPVVPPVSLQDPCKELPAEVVERSILESMVKPLTKSRGNFCCEWCSYQTPRRERWCDHMMKKHRSMVKILSSLRQQQEGTNLPDVPNKSAPSPTSNSTYLTMNAASREIPNTTVSNFRGSMGNSIMRPNSSASKFSPMSYPQMKPKSPHNSGLVNLTERSRYGMTDMTNSSADLETNSMLNDSSSDEELNEIDSENGLSAMDHQTSGLSAEQLMGSDGNKLLETKGIPFRRFMNRFQCPFCPFLTMHRRSISRHIENIHLSGKTAVYKCDECPFTCKSSLKLGAHKQCHTGTTSDWDAVNSQSESISSSLNEGVVSYESSSINGRKSGVMLDPLQQQQPPQPPPPPPPPPPSQPQPLQQPQPPQLQPPHQVPPQPQTQPPPTQQPQPPTQAAPLHPYKCTMCNYSTTTLKGLRVHQQHKHSFCDNLPKFEGQPSSLPLENETDSHPSSSNTVKKSQTSILGLSSKNNFVAKASRKLANDFPLDLSPVKKRTRIDEIASNLQSKINQTKQQEDAVINVEDDEEEEEDNEVEIEVELDREEEPTEPIIEVPTSFSAQQIWVRDTSEPQKEPNFRNITHDYNATNGAEIELTLSEDEEDYYGSSTNLKDHQVSNTALLNTQTPIYGTEHNSENTDFGDSGRLYYCKHCDFNNKSARSVSTHYQRMHPYIKFSFRYILDPNDHSAVYRCLECYIDYTNFEDLQQHYGEHHPEAMNVLNFDHSDLIYRCRFCSYTSPNVRSLMPHYQRMHPTVKINNAMIFSSYVVEQQEGLNTESQTLREILNSAPKNMATSTPVARGGGLPATFNKNTPKTFTPECENQKDPLVNTVVVYDCDVCSFASPNMHSVLVHYQKKHPEEKASYFRIQKTMRMVSVDRGSALSQLSFEVGAPMSPKMSNMGSPPPPQPPPPDLSTELYYCKHCSYSNRSVVGVLVHYQKRHPEIKVTAKYIRQAPPTAAMMRGVEGPQGSPRPPAPIQQLNRSSSERDGPPVENEMFFCQHCDYGNRTVKGVLIHYQKKHRDFKANADVIRQHTATIRSLCDRNQKKPASCVLVSPSNLERDKTKLRALKCRQCSYTSPYFYALRKHIKKDHPALKATVTSIMRWAFLDGLIEAGYHCEWCIYSHTEPNGLLLHYQRRHPEHYVDYTYMATKLWAGPDPSPPSLTMPAEAKTYRCRDCVFEAVSIWDITNHYQAFHPWAMNGDESVLLDIIKEKDAVEKPILSSEELAGPVNCENSIPTPFPEQEAECPEDARLSPEKSLQLASANPAISSTPYQCTVCQSEYNNLHGLLTHYGKKHPGMKVKAADFAQDIDINPGAVYKCRHCPYINTRIHGVLTHYQKRHPSIKVTAEDFVHDVEQSADISQNDVEETSRIFKQGYGAYRCKLCPYTHGTLEKLKIHYEKYHNQPEFDVFSQSPPKLPVPLEPEMTTEVSPSQVSITEEEVGEEPVSTSHFSTSHLVSHTVFRCQLCKYFCSTRKGIARHYRIKHNNVRAQPEGKNNLFKCALCAYTNPIRKGLAAHYQKRHDIDAYYTHCLAASRTISDKPNKVIIPSPPKDDSPQLSEELRRAVEKKKCSLCSFQSFSKKGIVSHYMKRHPGVFPKKQHASKLGGYFTAVYADEHEKPTLMEEEERGNFEKAEVEGEAQEIEWLPFRCIKCFKLSFSTAELLCMHYTDHHSRDLKRDFIILGNGPRLQNSTYQCKHCDSKLQSTAELTSHLNIHNEEFQKRAKRQERRKQLLSKQKYADGAFADFKQERPFGHLEEVPKIKERKVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPAVSAAVKGLRSHERSHLALAMFTREDKYSCQYCSFVSAFRHNLDRHMQTHHGHHKPFRCKLCSFKSSYNSRLKTHILKAHAGEHAYKCSWCSFSTMTISQLKEHSLKVHGKALTLPRPRIVSLLSSHSHHSSQKATPAEEVEDSNDSSYSEPPDVQQQLNHYQSAALARNNSRVSPVPLSGAAAGTEQKTEAVLHCEFCEFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTGFKSAFTMHVEAGHSAVPEEGPKDLRCPLCLYHTKYKRNMIDHIVLHREERVVPIEVCRSKLSKYLQGVVFRCDKCTFTCSSDESLQQHIEKHNELKPYKCQLCYYETKHTEELDSHLRDEHKVSRNFELVGRVNLDQLEQMKEKMESSSSDDEDKEEEMNSKAEDRELMRFSDHGAALNTEKRFPCEFCGRAFSQGSEWERHVLRHGMALNDTKQVSREEIHPKEIMENSVKMPSIEEKEDDEAIGIDFSLKNETVAICVVTADKSLLENAEAKKE", "length": 2506 }, "evidence": [ { "id": "RGD:1562123", "url": "https://alliancegenome.org/gene/RGD:1562123#orthology", "database": "AGR" }, { "id": "MGI:107690", "url": "https://alliancegenome.org/gene/MGI:107690#orthology", "database": "AGR" }, { "id": "HGNC:21684", "url": "https://alliancegenome.org/gene/HGNC:21684#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6997", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6997#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCW4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCW4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCW4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCW4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCW4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1003, "end_pos": 1005, "annotation": "n_glycosylation_sequon" }, { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1037, "end_pos": 1039, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1124, "end_pos": 1126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1377, "end_pos": 1379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1989, "end_pos": 1991, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2043, "end_pos": 2045, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2197, "end_pos": 2199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2444, "end_pos": 2446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 510, "end_pos": 512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 775, "end_pos": 777, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PCW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCW4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 109, "end_pos": 132, "start_aa": "Phe", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1067 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1003, "end_pos": 1005 }, { "start_pos": 102, "end_pos": 104 }, { "start_pos": 1037, "end_pos": 1039 }, { "start_pos": 1124, "end_pos": 1126 }, { "start_pos": 1377, "end_pos": 1379 }, { "start_pos": 1989, "end_pos": 1991 }, { "start_pos": 2043, "end_pos": 2045 }, { "start_pos": 2197, "end_pos": 2199 }, { "start_pos": 2444, "end_pos": 2446 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 510, "end_pos": 512 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 732, "end_pos": 734 }, { "start_pos": 775, "end_pos": 777 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PCX1-1", "uniprot_ac": "A0A8M9PCX1", "uniprot_id": "A0A8M9PCX1_DANRE", "mass": { "chemical_mass": 76982.0, "monoisotopic_mass": 76982.0 }, "refseq": { "ac": "XP_021328892", "name": "ribosomal protein S6 kinase-like 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328892" }, "gene_names": [ { "name": "rps6kl1", "type": "recommended", "evidence": [ { "id": "A0A8M9PCX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCX1" } ] }, { "name": "rps6kl1", "type": "synonym", "evidence": [ { "id": "XP_021328892", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328892" } ] } ], "protein_names": [ { "name": "Ribosomal protein S6 kinase-like 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PCX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCX1/entry#names_and_taxonomy" } ] }, { "name": "ribosomal protein S6 kinase-like 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021328892", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328892" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328892" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCX1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCX1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rps6kl1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCX1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-111020-10", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111020-10", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PCX1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PCX1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02677", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02677", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101886230", "url": "https://www.ncbi.nlm.nih.gov/gene/101886230", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007330", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007330", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036181", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036181", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051866", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051866", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101886230", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886230", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR15508", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15508", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15508:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15508:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04212", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04212", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021328892", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328892", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PCX1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HP54", "url": "https://www.uniprot.org/uniprotkb/A0AC58HP54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HP54-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HP54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-111020-10", "url": "https://zfin.org/ZDB-GENE-111020-10", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAKKDYLLDAAQQIRMALDREVNEDYEAAFSYYKNGVDLLLNGVQVDPNKERREAVKRKTTQYLKRAEEIFISYLQDNISKGSTHLGGYSSLRFRSIRHLSSPVENLAMCKVTGVIDKVLTVESLINKETFIVKSLPKSSWESRERSTIIPQGVPFMVKLLKYYVSEDTVFLHLEHLQGGRLFSRLHRVRSEAIREYPECFSPNQHKIYLKNSYTLPVLRQNTYLNEDYGRTSPPANHRLENCNPRSYCEDVGCQQTGSPSVFASDGLPSVGVPNGLNSLPQDNAPLPIHPCVIVDTRDPLDVTSDLLGNDVRIERIDSCVDLSKAWGALEPAQDCRGFTGSNSDILGFRIAAQITPSTLFGANAQPILCSTVNVLPQRVRIIPNASTKHQAHDGFPHEHNSPHRRPSGQQFVTEFHKVSSHRYSFECTPQNQDGFTLEFTNMTSRGNSGDLGKQDNCQFFSHSFTQPEVSMISCPSASTTNSACWSETYLEAGHRVNVAGLESKPQINTKNVGAKAKWGRRGLPEDEVRLWGAQILLALESLHEQGIVCQDLNPRNILLRSSGEACLTYFGQWTEVQPEINPKAMEEMYCAPEIGGVSKVTEACDWWSFGALLYELLTGMPLWQCHPAGVHPHTPLHIPEFLSTAATSLLTELLQFDACYRLGSGGGGVSDIKCHPFFSAVPWLKLSSS", "length": 690, "header": "tr|A0A8M9PCX1-1|A0A8M9PCX1_DANRE Isoform 1 of Ribosomal protein S6 kinase-like 1 isoform X1 OS=Danio rerio OX=7955 GN=rps6kl1 PE=4 SV=1 CANONICAL=A0A8M9PCX1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PCX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCX1/entry#A0A8M9PCX1-1", "sequence": { "sequence": "MAKKDYLLDAAQQIRMALDREVNEDYEAAFSYYKNGVDLLLNGVQVDPNKERREAVKRKTTQYLKRAEEIFISYLQDNISKGSTHLGGYSSLRFRSIRHLSSPVENLAMCKVTGVIDKVLTVESLINKETFIVKSLPKSSWESRERSTIIPQGVPFMVKLLKYYVSEDTVFLHLEHLQGGRLFSRLHRVRSEAIREYPECFSPNQHKIYLKNSYTLPVLRQNTYLNEDYGRTSPPANHRLENCNPRSYCEDVGCQQTGSPSVFASDGLPSVGVPNGLNSLPQDNAPLPIHPCVIVDTRDPLDVTSDLLGNDVRIERIDSCVDLSKAWGALEPAQDCRGFTGSNSDILGFRIAAQITPSTLFGANAQPILCSTVNVLPQRVRIIPNASTKHQAHDGFPHEHNSPHRRPSGQQFVTEFHKVSSHRYSFECTPQNQDGFTLEFTNMTSRGNSGDLGKQDNCQFFSHSFTQPEVSMISCPSASTTNSACWSETYLEAGHRVNVAGLESKPQINTKNVGAKAKWGRRGLPEDEVRLWGAQILLALESLHEQGIVCQDLNPRNILLRSSGEACLTYFGQWTEVQPEINPKAMEEMYCAPEIGGVSKVTEACDWWSFGALLYELLTGMPLWQCHPAGVHPHTPLHIPEFLSTAATSLLTELLQFDACYRLGSGGGGVSDIKCHPFFSAVPWLKLSSS", "length": 690, "header": "tr|A0A8M9PCX1-1|A0A8M9PCX1_DANRE Isoform 1 of Ribosomal protein S6 kinase-like 1 isoform X1 OS=Danio rerio OX=7955 GN=rps6kl1 PE=4 SV=1 CANONICAL=A0A8M9PCX1-1" }, "locus": {} }, { "isoform_ac": "A0AC58HP54-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCX1/entry#A0AC58HP54-1", "sequence": { "sequence": "MAKKDYLLDAAQQIRMALDREVNEDYEAAFSYYKNGVDLLLNGVQVDPNKERREAVKRKTTQYLKRAEEIFISYLQDNISKGSTHLGGYSSLRFRSIRHLSSPVENLAMCKVTGVIDKVLTVESLINKETFIVKSLPKSSWESRERSTIIPQGVPFMVKLLKYYVSEDTVFLHLEHLQGEACLTYFGQWTEVQPEINPKAMEEMYCAPEIGGVSKVTEACDWWSFGALLYELLTGMPLWQCHPAGVHPHTPLHIPEFLSTAATSLLTELLQFDACYRLGSGGGGVSDIKCHPFFSAVPWLKLSSS", "length": 305, "header": "tr|A0AC58HP54-1|A0AC58HP54_DANRE Computationally mapped isoform of Ribosomal protein S6 kinase-like 1 isoform X2 OS=Danio rerio OX=7955 GN=rps6kl1 PE=4 SV=1 CANONICAL=A0A8M9PCX1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101886230", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886230", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AKT7-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Rps6kl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLVACECPPGPGLEPEPCSRARSQACMYLEQIRHWVAAGTADMTKRDYLVDAATQIHLALERDVSEDYEAAFNYYQNGVDVLLRGVHVDPNKERCEAVKLKITKYLRRAEEIFNCHLQRTLGSGTSPNTGFSSLRLRPIRTLSSALEQLKGCRVVGIIKKSLPRCHMVSRERLTIIPHGVPFMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQDHFQHSGLKSGSAQEKCKVQLSTGHNLTTPAKLPPGHTLRQDRTPVEPPWTSQSLPPALQLQKEADGEPAPRTSIVYSSDLTEAPCGHLHSQVRRAGQSSNPAPSQRLHWVREGADRVLGAYGRGRAQNPPSANRASLGSGRAAWSLWEGQVKQWAAEMLLALEALHEQGVLCRDLNPQNLLLDQAGHIQLTYFGQWSEVEPQCSQEAVDCLYSAPEVGGISELTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSRPAASLLTELLQFDPQRRLGAGGGGTSKLKSHPFFSSIQWSRLTG", "length": 528 }, "evidence": [ { "id": "HGNC:20222", "url": "https://alliancegenome.org/gene/HGNC:20222#orthology", "database": "AGR" }, { "id": "MGI:2443413", "url": "https://alliancegenome.org/gene/MGI:2443413#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R2S1-1", "protein_name": "Ribosomal protein S6 kinase-like 1", "gene_name": "Rps6kl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLVACECPPGPGLEPEPCSRARSQACMYLEQIRNRVATGTADVTKRDYLVDAATQIHLALERDVSEDYEAAFNHYQNGVDVLLRGVHVDPNKERREAVKLKITKYLRRAEEIFNCHLQRTLGSGASPNTGFSSLRLRPIRTLSSALEQLKGCRVVGIIKKVQVVQDPATGGTFIVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQDHFQYSGLNSGSVQEKSQAQLSTRLSLMTPAELTPGHTLRQNRIPMEPPRTSQSLPPALQLQKEADAEPSSRPSAVFSSDPTEAPCGHSHSQVRRAGQSSNPAPTQRLHWVREGADRVLGAYGRGRGRNPPSANRASLGSGRAAWSLREGQVKQWAAEMLLALEALHQQGVLCRDLNPQNLLLDQAGHIQLTYFGQWSEVEPRCSQEAVDCLYSAPEVGGISELTEACDWWSYGSLLYELLTGMALSQSHPSGFQAHTQLQLPEWLSHPAASLLTELLQFEPQRRLGAGGGGTSRLKSHPFFSTIQWSRLMG", "length": 544 }, "evidence": [ { "id": "HGNC:20222", "url": "https://alliancegenome.org/gene/HGNC:20222#orthology", "database": "AGR" }, { "id": "MGI:2443413", "url": "https://alliancegenome.org/gene/MGI:2443413#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111020-10", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111020-10#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VEA9-1", "protein_name": "Ribosomal protein S6 kinase delta-1", "gene_name": "Dmel\\CG7156", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTLNLGGWIHSFTVTDTQEHKGGYTIYKITSIVFPRSVPQALTCLVVWKRFHDVKRLHRELSRRHKSLQLPGKLPVPTDSTYFKRFDAAVIQRRKEYILQLLDFAAQHPALYKCSTFTQFFQETPSPNGSPLKKLYVERSLRLQTEDNGCGSGGSETGTCAGAIADICDKLDLPYDPHDAGGITPLDPRCDKEQTNNESQAKETEIELETKQEPKTDVALTKRDYLRLLTPMASIESDDSDYIYEAALEFSHAVQAEVNLEYAEAHERYKHGVDLLLNGAKQDSSEERRFIAKAKIAKYLARAEEIHANFLANDCPTKKLQFQLSLDTTDGGSVSHLECPWNQLARYKVLQILQDRVMQVQCVTKSQQPAAIMKGVEKPASHSLTQSIFLPQQVPYMVQLLAYFQSEQKIFLLLRQAEGGMLYDYLQSYTPTSSKSVNYGELFPSDQEPEEKEAEEPPLTSDSDVSDLVRSSQQLLKSVTNTLSNLQAGVVTPKRNKKVDQNRIRSKPIPEQCLRQWACELAIAIHSLHGKGVILRDLHMGNILLGAKGQLLLTYFYQNEGLTSDDNYVHKALNLEAVANHFVAPERPLTFRSDWWSYGVVLYQLLLGVPYKVTHPGQLDLYGCVQYPSESLEISDHAKDLLEQLLQLSPELRLDYDQLQAHPFFKGIDWQAVLEQGTESM", "length": 681 }, "evidence": [ { "id": "HGNC:20222", "url": "https://alliancegenome.org/gene/HGNC:20222#orthology", "database": "AGR" }, { "id": "MGI:2443413", "url": "https://alliancegenome.org/gene/MGI:2443413#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y6S9-1", "protein_name": "Ribosomal protein S6 kinase-like 1", "gene_name": "RPS6KL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLVACECLPSPGLEPEPCSRARSQAHVYLEQIRNRVALGVPDMTKRDYLVDAATQIRLALERDVSEDYEAAFNHYQNGVDVLLRGIHVDPNKERREAVKLKITKYLRRAEEIFNCHLQRPLSSGASPSAGFSSLRLRPIRTLSSAVEQLRGCRVVGVIEKVQLVQDPATGGTFVVKSLPRCHMVSRERLTIIPHGVPYMTKLLRYFVSEDSIFLHLEHVQGGTLWSHLLSQAHSRHSGLSSGSTQERMKAQLNPHLNLLTPARLPSGHAPGQDRIALEPPRTSPNLLLAGEAPSTRPQREAEGEPTARTSTSGSSDLPKAPGGHLHLQARRAGQNSDAGPPRGLTWVPEGAGPVLGGCGRGMDQSCLSADGAGRGCGRATWSVREEQVKQWAAEMLVALEALHEQGVLCRDLHPGNLLLDQAGHIRLTYFGQWSEVEPQCCGEAVDNLYSAPEVGGISELTEACDWWSFGSLLYELLTGMALSQSHPSGIQAHTQLQLPEWLSRPAASLLTELLQFEPTRRLGMGEGGVSKLKSHPFFSTIQWSKLVG", "length": 549 }, "evidence": [ { "id": "HGNC:20222", "url": "https://alliancegenome.org/gene/HGNC:20222#orthology", "database": "AGR" }, { "id": "MGI:2443413", "url": "https://alliancegenome.org/gene/MGI:2443413#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111020-10", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111020-10#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCX1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCX1" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PCX1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCX1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 385, "end_pos": 387, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PCX1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCX1" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 355, "end_pos": 679, "start_aa": "Ile", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 385, "end_pos": 387 }, { "start_pos": 442, "end_pos": 444 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { 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record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021324738.1. 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"MPEKARQRSTQVYQHYLYTVTDSSECSSEKEEDEEPSKRLTPLEKLTLEMCKDENTVKELTVGKRVGFYKVRGQIGCGNFSKVKLATHALTKDKVAVKIMDKMRLDVQTQRMLTREISNMESLYHPNLLQLFEVLETPSRLYLILEFAGGGDLHTRISSGGKLTDLESKIVFAQILSAVKYMHENNIIHRDLKAENVLYTTNGCIKVADFGFSTKVNNRNQALDTFCGSPPYAAPELFKDDSYIGPPVDVWAMGVLLFFMVTGSLPFRADTVPKLRQSVLEGAYVLPIWVSAPCQRLIRGILKPEPSERCALDQMLGCEWLLPVELFRPIPPLYQLNPIHLLEAGPGELDRDQEEVKGILEKLGVTPEHILNNQGKRIRSPINGVYRILLHRVKRNRGAESVPSISGVVKDPKRDSLRAYRNLRHSSKLCALS", "length": 433, "header": "tr|A0A8M9PD81-1|A0A8M9PD81_DANRE Isoform 1 of non-specific serine/threonine protein kinase OS=Danio rerio OX=7955 GN=nim1kb PE=3 SV=2 CANONICAL=A0A8M9PD81-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PD81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD81/entry#A0A8M9PD81-1", "sequence": { "sequence": "MPEKARQRSTQVYQHYLYTVTDSSECSSEKEEDEEPSKRLTPLEKLTLEMCKDENTVKELTVGKRVGFYKVRGQIGCGNFSKVKLATHALTKDKVAVKIMDKMRLDVQTQRMLTREISNMESLYHPNLLQLFEVLETPSRLYLILEFAGGGDLHTRISSGGKLTDLESKIVFAQILSAVKYMHENNIIHRDLKAENVLYTTNGCIKVADFGFSTKVNNRNQALDTFCGSPPYAAPELFKDDSYIGPPVDVWAMGVLLFFMVTGSLPFRADTVPKLRQSVLEGAYVLPIWVSAPCQRLIRGILKPEPSERCALDQMLGCEWLLPVELFRPIPPLYQLNPIHLLEAGPGELDRDQEEVKGILEKLGVTPEHILNNQGKRIRSPINGVYRILLHRVKRNRGAESVPSISGVVKDPKRDSLRAYRNLRHSSKLCALS", "length": 433, "header": "tr|A0A8M9PD81-1|A0A8M9PD81_DANRE Isoform 1 of non-specific serine/threonine protein kinase OS=Danio rerio OX=7955 GN=nim1kb PE=3 SV=2 CANONICAL=A0A8M9PD81-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "dre:797096", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797096", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ACD6B7I0-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "nim1ka", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTAVYPAVGVSVGVSSVGPQRYARWSRQDSSDICTDDEGTQARRLTPLEKLNLDMCQDEKMVRELTVGRRIGFYKIRGEIGCGNFSHVKLGIHALTKDKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLTRLHLVMEYAGGGELYTKISTEGKLSDIDSKIVFSQVLSAVKHMHDNNIIHRDMKAENVFYTCSTCVKVGDFGFSTVSRRDETLNTFCGSPPYAAPELFRDEHYIGVCVDIWALGVMLFFMVTGTMPFRAETVAKLKRCILDGTYTVPTWVPEPCQKLIRGILQPQPSDRCSVEQMMACEWLQPVEFPKAMEPFKLDPHHLVESGPGELEEHEIEVRNALEMFGITAEHIRNNQGKDCRSSITGVYRILLHRAHKRQAVESMPVVTHVVNGTDAKKERLKTYRSLRHTSKLCIIL", "length": 438 }, "evidence": [ { "id": "RGD:1308116", "url": "https://alliancegenome.org/gene/RGD:1308116#orthology", "database": "AGR" }, { "id": "HGNC:28646", "url": "https://alliancegenome.org/gene/HGNC:28646#orthology", "database": "AGR" }, { "id": "MGI:2442399", "url": "https://alliancegenome.org/gene/MGI:2442399#orthology", "database": "AGR" }, { "id": "FB:FBgn0031299", "url": "https://alliancegenome.org/gene/FB:FBgn0031299#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A9H8-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "Nim1k", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAVVVNGGGLVNTHCDRWDRRDSAEGSCQTEGSKDGEEDQPRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSSTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGAYSIPQHVSEPCHRLIRGVLQPTPAERYGINYIMSNEWMRGVPYPSPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITDEHIRNNQGRDARSSITGVYRIILHRVQRRKALESVPMATLPEPKDKDLKKGSRVYRGIRHTSKFCSIL", "length": 436 }, "evidence": [ { "id": "RGD:1308116", "url": "https://alliancegenome.org/gene/RGD:1308116#orthology", "database": "AGR" }, { "id": "HGNC:28646", "url": "https://alliancegenome.org/gene/HGNC:28646#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-283#orthology", "database": "AGR" }, { "id": "MGI:2442399", "url": "https://alliancegenome.org/gene/MGI:2442399#orthology", "database": "AGR" }, { "id": "FB:FBgn0031299", "url": "https://alliancegenome.org/gene/FB:FBgn0031299#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13186-1", "protein_name": "Serine/threonine-protein kinase KIN2", "gene_name": "KIN2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPNPNTADYLVNPNFRTSKGGSLSPTPEAFNDTRVAAPATLRMMGKQSGPRNDQQQAPLMPPADIKQGKEQAAQRQNDASRPNGAVELRQFHRRSLGDWEFLETVGAGSMGKVKLVKHRQTKEICVIKIVNRASKAYLHKQHSLPSPKNESEILERQKRLEKEIARDKRTVREASLGQILYHPHICRLFEMCTMSNHFYMLFEYVSGGQLLDYIIQHGSLKEHHARKFARGIASALQYLHANNIVHRDLKIENIMISSSGEIKIIDFGLSNIFDYRKQLHTFCGSLYFAAPELLKAQPYTGPEVDIWSFGIVLYVLVCGKVPFDDENSSILHEKIKKGKVDYPSHLSIEVISLLTRMIVVDPLRRATLKNVVEHPWMNRGYDFKAPSYVPNRVPLTPEMIDSQVLKEMYRLEFIDDIEDTRRSLIRLVTEKEYIQLSQEYWDKLSNAKGLSSSLNNNYLNSTAQQTLIQNHITSNPSQSGYNEPDSNFEDPTLAYHPLLSIYHLVSEMVARKLAKLQRRQALALQAQAQQRQQQQQVALGTKVALNNNSPDIMTKMRSPQKEVVPNPGIFQVPAIGTSGTSNNTNTSNKPPLHVMVPPKLTIPEQAHTSPTSRKSSDIHTELNGVLKSTPVPVSGEYQQRSASPVVGEHQEKNTIGGIFRRISQSGQSQHPTRQQEPLPEREPPTYMSKSNEISIKVPKSHSRTISDYIPSARRYPSYVPNSVDVKQKPAKNTTIAPPIRSVSQKQNSDLPALPQNAELIVQKQRQKLLQENLDKLQINDNDNNNVNAVVDGINNDNSDHYLSVPKGRKLHPSARAKSVGHARRESLKFTRPPIPAALPPSDMTNDNGFLGEANKERYNPVSSNFSTVPEDSTTYSNDTNNRLTSVYSQELTEKQILEEASKAPPGSMPSIDYPKSMFLKGFFSVQTTSSKPLPIVRHNIISVLTRMNIDFKEVKGGFICVQQRPSIETAAVPVITTTGVGLDSGKAMDLQNSLDSQLSSSYHSTASSASRNSSIKRQGSYKRGQNNIPLTPLATNTHQRNSSIPMSPNYGNQSNGTSGELSSMSLDYVQQQDDILTTSRAQNINNVNGQTEQTNTSGIKERPPIKFEIHIVKVRIVGLAGVHFKKVSGNTWLYKELASYILKELNL", "length": 1147 }, "evidence": [ { "id": "RGD:1308116", "url": "https://alliancegenome.org/gene/RGD:1308116#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8BHI9-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "Nim1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAVFVNGGGLVNTHCDRWERRDSVESSCQTEGGKDSEEDQQRQLTPFEKLTQDMCQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIVRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQILSAVKHMHENQIIHRDLKAENVFYTSRTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDQHYVGVYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYTIPQHVSEPCHRLIRGVLQPTPTERYGINYIMSNEWMRGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITDEHIRNNQGRDARSSITGVYRIILHRVQRRKALESVPIMILPEPKERDLKKGSRIYRGIRHTSKFCSIL", "length": 436 }, "evidence": [ { "id": "RGD:1308116", "url": "https://alliancegenome.org/gene/RGD:1308116#orthology", "database": "AGR" }, { "id": "HGNC:28646", "url": "https://alliancegenome.org/gene/HGNC:28646#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-283#orthology", "database": "AGR" }, { "id": "MGI:2442399", "url": "https://alliancegenome.org/gene/MGI:2442399#orthology", "database": "AGR" }, { "id": "FB:FBgn0031299", "url": "https://alliancegenome.org/gene/FB:FBgn0031299#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IY84-1", "protein_name": "Serine/threonine-protein kinase NIM1", "gene_name": "NIM1K", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAVYMNGGGLVNPHYARWDRRDSVESGCQTESSKEGEEGQPRQLTPFEKLTQDMSQDEKVVREITLGKRIGFYRIRGEIGSGNFSQVKLGIHSLTKEKVAIKILDKTKLDQKTQRLLSREISSMEKLHHPNIIRLYEVVETLSKLHLVMEYAGGGELFGKISTEGKLSEPESKLIFSQIVSAVKHMHENQIIHRDLKAENVFYTSNTCVKVGDFGFSTVSKKGEMLNTFCGSPPYAAPELFRDEHYIGIYVDIWALGVLLYFMVTGTMPFRAETVAKLKKSILEGTYSVPPHVSEPCHRLIRGVLQQIPTERYGIDCIMNDEWMQGVPYPTPLEPFQLDPKHLSETSTLKEEENEVKSTLEHLGITEEHIRNNQGRDARSSITGVYRIILHRVQRKKALESVPVMMLPDPKERDLKKGSRVYRGIRHTSKFCSIL", "length": 436 }, "evidence": [ { "id": "RGD:1308116", "url": "https://alliancegenome.org/gene/RGD:1308116#orthology", "database": "AGR" }, { "id": "HGNC:28646", "url": "https://alliancegenome.org/gene/HGNC:28646#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-283#orthology", "database": "AGR" }, { "id": "MGI:2442399", "url": "https://alliancegenome.org/gene/MGI:2442399#orthology", "database": "AGR" }, { "id": "FB:FBgn0031299", "url": "https://alliancegenome.org/gene/FB:FBgn0031299#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VPW3-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "anon-WO0257455.15", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRSSATVKVTSAATPPHPPPLTTTTTPLTICQPPPPTPPYQRLTKALQCDPRCGHEVTIGRRIGLYRFCGDIGRGNFSKVKLAVHQLTRDKVAIKVVDLDRAGLDAKALRMLSSEIATLECVHHPNILRLFEVVETLGRVYLVTEWIRGGELYNHITQGGPLREIHAAPLLKQLLLAVKHMHSLGYVHRDIKAENVLLLSEDRLKLADFGFSTQLINGANQKLDTFCGSPPYAAPELFSDDHYIGAPVDVWALGILLYFMVVGNMPFRAPTIPGLKAAILKGDYLLPGQLSLPCIRLIQRILIHIPAQRPTIDDMLNSQFVTCPKLSADLMQWEINQHTKPVKRSIFWVRSKSHRLRKSASLRDRYAEVVKKPAISMNTRQQDEMFVQNFLQPIEMGHELLVPVSSQLKEPQSTEQAKRPTRRYMFCGSLKKKVTPMETEPEKQLANGGQSIGSAKINPWNVEVAEDCPLFKNYDAETGSCVMLPTNTEDLSQLGALEFEARQILAELGLTSEMLINARQSGPRSDIIGAYRIVVNRLQKQSWLARKHVEMALHSEPKVEKRIERSCCIL", "length": 570 }, "evidence": [ { "id": "RGD:1308116", "url": "https://alliancegenome.org/gene/RGD:1308116#orthology", "database": "AGR" }, { "id": "HGNC:28646", "url": "https://alliancegenome.org/gene/HGNC:28646#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-283#orthology", "database": "AGR" }, { "id": "MGI:2442399", "url": "https://alliancegenome.org/gene/MGI:2442399#orthology", "database": "AGR" }, { "id": "FB:FBgn0031299", "url": "https://alliancegenome.org/gene/FB:FBgn0031299#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD81" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD81" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD81" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "17989", "name": "", "equation": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8M1PSK1-1", "A0A8M1PT23-1", "A0A8M1PVD6-1", "Q6DGS3-1", "A0A8M9PYJ9-1", "A0A8M2B3S3-1", "C5J7W8-1", "A0A8M9QDG2-1", "A7MBL8-1", "A8WIP6-1", "F1QGZ6-1", "F1QU13-1", "Q1ECX4-1", "A0A8M9QA37-1", "F1R6Y1-1", "A0A8M3B3H5-1", "A0A8M3BAY8-1", "A0A8M3AUY8-1", "A0A8M3AV72-1", "A0A8M3AXV9-1", "A0AC58JM51-1", "A0A8M6Z299-1", "A0A8M9P416-1", "F1QM17-1", "A0A8M3B8F4-1", "A0A8M2B2E6-1", "A0A8M9P5C7-1", "A0A8M9P2Q2-1", "A0A8M9Q3H8-1", "A0A8M2B3P7-1", "A0ACD6B7V3-1", "A0A8M9Q9K2-1", "A5WUM0-1", "Q6NW76-1", "F1Q5H3-1", "F1QB90-1", "A0A8M2BCS1-1", "A0A8M3AQT9-1", "A0ACD6B5Y1-1", "A0A8M3AY27-1", "A0A8M6YZP6-1", "A0AB32TX22-1", "A0A8M1RIB3-1", "A0A8M3AXQ6-1", "A0A8M9PTI7-1", "A0A8M9PXY8-1", "A0A8M9PST9-1", "A0A8M9PZ45-1", "A0A8M3AXB0-1", "A0A8M9QFR9-1", "A0A8M9QHE0-1", "A0A8N7TD19-1", "Q7ZTW4-1", "A0A8M2BA19-1", "A0A8M3AL82-1", "Q6P3K7-1", "Q7SXE8-1", "Q7SY24-1", "Q7T2E3-1", "Q7ZUQ3-1", "Q7ZUS1-1", "Q7ZVS3-1", "Q8AYG3-1", "Q90XC2-1", "Q90XF2-1", "Q9DGD9-1", "Q9DGE0-1", "Q9DGE1-1", "Q9DGE2-1", "A0A8M2BAL6-1", "Q4VSN1-1", "Q6DBX4-1", "A0A0R4IJZ0-1", 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"name": "", "equation": "L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8M1PSK1-1", "A0A8M1PT23-1", "A0A8M1PVD6-1", "Q6DGS3-1", "A0A8M9PYJ9-1", "A0A8M2B3S3-1", "C5J7W8-1", "A0A8M9QDG2-1", "A7MBL8-1", "A8WIP6-1", "F1QGZ6-1", "F1QU13-1", "Q1ECX4-1", "A0A8M9QA37-1", "F1R6Y1-1", "A0A8M3B3H5-1", "A0A8M3BAY8-1", "A0A8M3AUY8-1", "A0A8M3AV72-1", "A0A8M3AXV9-1", "A0AC58JM51-1", "A0A8M6Z299-1", "A0A8M9P416-1", "F1QM17-1", "A0A8M3B8F4-1", "A0A8M2B2E6-1", "A0A8M9P5C7-1", "A0A8M9P2Q2-1", "A0A8M9Q3H8-1", "A0A8M2B3P7-1", "A0ACD6B7V3-1", "A0A8M9Q9K2-1", "A5WUM0-1", "Q6NW76-1", "F1Q5H3-1", "F1QB90-1", "A0A8M9PXR5-1", "A0A8M1NB85-1", "A0A8M2BCS1-1", "A0A8M3AQT9-1", "A0ACD6B5Y1-1", "A0A8M3AY27-1", "A0A8M6YZP6-1", "A0AB32TX22-1", "A0A8M1RIB3-1", "A0A8M3AXQ6-1", "A0A8M9PTI7-1", "A0A8M9PXY8-1", "A0A8M9PST9-1", "A0A8M9PZ45-1", "A0A8M3AXB0-1", "A0A8M9QFR9-1", 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ADP + H(+).", "evidence": [ { "id": "A0A8M1QL80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1QL80" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M1QL80", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1QL80" } ] } ] }, { "uniprot_ac": "A0A8M1QLR0", "gene_name": "cdk19", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M1QLR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1QLR0" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8M1QLR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1QLR0" } ] } ] }, { "uniprot_ac": "A0A8M1QQI8", "gene_name": "ern2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M1QQI8", "database": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M1RNJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1RNJ3" } ] } ] }, { "uniprot_ac": "A0A8M1RNL4", "gene_name": "plk2a", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M1RNL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1RNL4" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8M1RNL4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1RNL4" } ] } ] }, { "uniprot_ac": "A0A8M1RP57", "gene_name": "LOC100534990", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M1RP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1RP57" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M1RP57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1RP57" } ] } ] }, { "uniprot_ac": "A0A8M1RRA7", "gene_name": "si:ch73-60h1.1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M1RRA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1RRA7" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8M1RRA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1RRA7" } ] } ] }, { "uniprot_ac": "A0A8M2B1T7", "gene_name": "LOC559131", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2B1T7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B1T7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M2B1T7", "database": "UniProtKB", "url": 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"ec_number": "2.7.12.2", "activity": "", "evidence": [ { "id": "A0A8M2BBT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BBT8" } ] } ] }, { "uniprot_ac": "A0A8M2BCS1", "gene_name": "mark4a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2BCS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BCS1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M2BCS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BCS1" } ] } ] }, { "uniprot_ac": "A0A8M2BCZ3", "gene_name": "rps6ka4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2BCZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BCZ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"uniprot_ac": "A0A8M2BIW9", "gene_name": "csnk1g2a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2BIW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BIW9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M2BIW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BIW9" } ] } ] }, { "uniprot_ac": "A0A8M2BJ77", "gene_name": "camkk1a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2BJ77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BJ77" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8M2BJ77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BJ77" } ] } ] }, { "uniprot_ac": "A0A8M2BKH6", "gene_name": "nek12", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2BKH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BKH6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M2BKH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BKH6" } ] } ] }, { "uniprot_ac": "A0A8M2BLD7", "gene_name": "LOC101885029", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M2BLD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BLD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M2BLD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BLD7" } ] } ] }, { "uniprot_ac": "A0A8M3AJH8", "gene_name": "nek10", "activity": [ { "ec_number": "2.7.11.1", "activity": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3APA4" } ] } ] }, { "uniprot_ac": "A0A8M3AQI8", "gene_name": "pimr108", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3AQI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AQI8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3AQI8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AQI8" } ] } ] }, { "uniprot_ac": "A0A8M3AQT9", "gene_name": "taok2a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3AQT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AQT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3AQT9", "database": "UniProtKB", "url": 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"uniprot_ac": "A0A8M3AUY8", "gene_name": "si:dkey-37m8.3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3AUY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AUY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3AUY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AUY8" } ] } ] }, { "uniprot_ac": "A0A8M3AV72", "gene_name": "LOC101883541", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3AV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AV72" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3AV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AV72" } ] } ] }, { "uniprot_ac": "A0A8M3AV76", "gene_name": "LOC568680", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3AV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AV76" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3AV76", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AV76" } ] } ] }, { "uniprot_ac": "A0A8M3AXB0", "gene_name": "camk2b2", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3AXB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AXB0" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8M3AXB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AXB0" } ] } ] }, { "uniprot_ac": "A0A8M3AXH0", "gene_name": "mast3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3AXH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AXH0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3AXH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AXH0" } ] } ] }, { "uniprot_ac": "A0A8M3AXQ6", "gene_name": "mast1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3AXQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AXQ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3AXQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AXQ6" } ] } ] }, { "uniprot_ac": "A0A8M3AXV9", "gene_name": "pimr98", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3AXV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AXV9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3AXV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AXV9" } ] } ] }, { "uniprot_ac": "A0A8M3AY27", "gene_name": "taok2b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3AY27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AY27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3AY27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AY27" } ] } ] }, { "uniprot_ac": "A0A8M3B214", "gene_name": "LOC796099", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3B214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B214" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3B214", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B214" } ] } ] }, { "uniprot_ac": "A0A8M3B300", "gene_name": "dmpk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3B300", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B300" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3B300", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B300" } ] } ] }, { "uniprot_ac": "A0A8M3B3H5", "gene_name": "pimr147", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3B3H5", "database": "UniProtKB", "url": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3B435", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B435" } ] } ] }, { "uniprot_ac": "A0A8M3B4V1", "gene_name": "mark2a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3B4V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B4V1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3B4V1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B4V1" } ] } ] }, { "uniprot_ac": "A0A8M3B572", "gene_name": "LOC101883933", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3B572", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B572" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { 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"activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3BAY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BAY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M3BAY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BAY8" } ] } ] }, { "uniprot_ac": "A0A8M3BC62", "gene_name": "cdk11b", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3BC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BC62" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "A0A8M3BC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BC62" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "A0A8M3BC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BC62" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8M3BC62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BC62" } ] } ] }, { "uniprot_ac": "A0A8M3BCH5", "gene_name": "pikfyve", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M3BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BCH5" } ] }, { "ec_number": "2.7.1.150", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,5-bisphosphate) + ADP + H(+).", "evidence": [ { "id": "A0A8M3BCH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BCH5" } ] }, { "ec_number": "2.7.1.150", "activity": "", "evidence": [ { "id": 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M6YZP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YZP6" } ] } ] }, { "uniprot_ac": "A0A8M6Z057", "gene_name": "caska", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M6Z057", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z057" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M6Z057", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z057" } ] } ] }, { "uniprot_ac": "A0A8M6Z0R7", "gene_name": "LOC797120", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M6Z0R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0R7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": 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"url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Q2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9P2Q2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Q2" } ] } ] }, { "uniprot_ac": "A0A8M9P416", "gene_name": "LOC110438238", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9P416", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P416" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9P416", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P416" } ] } ] }, { "uniprot_ac": "A0A8M9P5C7", "gene_name": "si:ch211-220i18.4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9P5C7", "database": "UniProtKB", "url": 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"https://www.uniprot.org/uniprotkb/A0A8M9PA89" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PA89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PA89" } ] } ] }, { "uniprot_ac": "A0A8M9PBH7", "gene_name": "pimr80", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBH7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PBH7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBH7" } ] } ] }, { "uniprot_ac": "A0A8M9PCE9", "gene_name": "LOC110437906", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCE9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PCE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCE9" } ] } ] }, { "uniprot_ac": "A0A8M9PD73", "gene_name": "cdk14", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PD73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD73" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A0A8M9PD73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD73" } ] } ] }, { "uniprot_ac": "A0A8M9PD81", "gene_name": "nim1kb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PD81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD81" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PD81", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD81" } ] } ] }, { "uniprot_ac": "A0A8M9PDN1", "gene_name": "pimr211", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PDN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDN1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PDN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDN1" } ] } ] }, { "uniprot_ac": "A0A8M9PEY3", "gene_name": "LOC562898", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PEY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PEY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEY3" } ] } ] }, { "uniprot_ac": "A0A8M9PFU6", "gene_name": "alpk3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PFU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFU6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PFU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFU6" } ] } ] }, { "uniprot_ac": "A0A8M9PH28", "gene_name": "LOC108180115", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PH28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH28" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PH28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH28" } ] } ] }, { "uniprot_ac": "A0A8M9PHK4", "gene_name": "LOC110438410", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PHK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHK4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PHK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHK4" } ] } ] }, { "uniprot_ac": "A0A8M9PHY3", "gene_name": "pimr113", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PHY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHY3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PHY3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHY3" } ] } ] }, { "uniprot_ac": "A0A8M9PJD6", "gene_name": "LOC563925", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PJD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJD6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PJD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJD6" } ] } ] }, { "uniprot_ac": "A0A8M9PKB0", "gene_name": "si:ch211-151m7.3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PKB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKB0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PKB0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKB0" } ] } ] }, { "uniprot_ac": "A0A8M9PLD4", "gene_name": "prkd2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PLD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD4" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0A8M9PLD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD4" } ] } ] }, { "uniprot_ac": "A0A8M9PLT9", "gene_name": "LOC100333446", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PLT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLT9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PLT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLT9" } ] } ] }, { "uniprot_ac": "A0A8M9PM31", "gene_name": "prkcaa", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + 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"ec_number": "2.7.11.39", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PP53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PP53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP53" } ] }, { "ec_number": "2.7.11.39", "activity": "", "evidence": [ { "id": "A0A8M9PP53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP53" } ] } ] }, { "uniprot_ac": "A0A8M9PPY9", "gene_name": "mast3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PPY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPY9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PPY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPY9" } ] } ] }, { "uniprot_ac": "A0A8M9PQA7", "gene_name": "chek1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PQA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQA7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PQA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQA7" } ] } ] }, { "uniprot_ac": "A0A8M9PQC1", "gene_name": "pimr100", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PQC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQC1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PQC1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQC1" } ] } ] }, { "uniprot_ac": "A0A8M9PR69", "gene_name": "citb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PR69" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PR69", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PR69" } ] } ] }, { "uniprot_ac": "A0A8M9PR86", "gene_name": "LOC100001608", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PR86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PR86" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PR86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PR86" } ] } ] }, { "uniprot_ac": "A0A8M9PS28", "gene_name": "LOC100006975", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PS28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS28" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PS28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS28" } ] } ] }, { "uniprot_ac": "A0A8M9PST9", "gene_name": "LOC110438304", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PST9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PST9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PST9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PST9" } ] } ] }, { "uniprot_ac": "A0A8M9PT65", "gene_name": "si:dkey-93l1.6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PT65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PT65" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PT65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PT65" } ] } ] }, { "uniprot_ac": "A0A8M9PTF5", "gene_name": "LOC797974", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PTF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTF5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PTF5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTF5" } ] } ] }, { "uniprot_ac": "A0A8M9PTH9", "gene_name": "pimr124", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PTH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTH9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PTH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTH9" } ] } ] }, { "uniprot_ac": "A0A8M9PTI7", "gene_name": "wnk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTI7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PTI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTI7" } ] } ] }, { "uniprot_ac": "A0A8M9PVD4", "gene_name": "ttbk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PVD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PVD4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PVD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PVD4" } ] } ] }, { "uniprot_ac": "A0A8M9PW52", "gene_name": "LOC103910699", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PW52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PW52" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PW52", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PW52" } ] } ] }, { "uniprot_ac": "A0A8M9PWP2", "gene_name": "wnk4a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PWP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PWP2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PWP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PWP2" } ] } ] }, { "uniprot_ac": "A0A8M9PXN3", "gene_name": "mark3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PXN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PXN3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PXN3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PXN3" } ] } ] }, { "uniprot_ac": "A0A8M9PXR5", "gene_name": "tnk2b", "activity": [ { "ec_number": "2.7.10.2", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PXR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PXR5" } ] }, { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PXR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PXR5" } ] }, { "ec_number": "2.7.10.2", "activity": "", "evidence": [ { "id": "A0A8M9PXR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PXR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PXR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PXR5" } ] } ] }, { "uniprot_ac": "A0A8M9PXY8", "gene_name": "wnk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PXY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PXY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PXY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PXY8" } ] } ] }, { "uniprot_ac": "A0A8M9PYJ9", "gene_name": "srpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PYJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PYJ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PYJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PYJ9" } ] } ] }, { "uniprot_ac": "A0A8M9PZ45", "gene_name": "alpk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PZ45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PZ45" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PZ45", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PZ45" } ] } ] }, { "uniprot_ac": "A0A8M9PZH2", "gene_name": "LOC796922", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PZH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PZH2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PZH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PZH2" } ] } ] }, { "uniprot_ac": "A0A8M9PZU3", "gene_name": "prkacaa", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PZU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PZU3" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0A8M9PZU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PZU3" } ] } ] }, { "uniprot_ac": "A0A8M9PZZ9", "gene_name": "LOC110439848", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9PZZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PZZ9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9PZZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PZZ9" } ] } ] }, { "uniprot_ac": "A0A8M9Q057", "gene_name": "pimr145", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q057", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q057" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9Q057", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q057" } ] } ] }, { "uniprot_ac": "A0A8M9Q118", "gene_name": "prkg2l", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q118", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q118" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8M9Q118", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q118" } ] } ] }, { "uniprot_ac": "A0A8M9Q144", "gene_name": "si:dkey-112g5.3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q144", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q144" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9Q144", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q144" } ] } ] }, { "uniprot_ac": "A0A8M9Q2S7", "gene_name": "prkg2", "activity": [ { "ec_number": "2.7.11.12", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2S7" } ] }, { "ec_number": "2.7.11.12", "activity": "", "evidence": [ { "id": "A0A8M9Q2S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2S7" } ] } ] }, { "uniprot_ac": "A0A8M9Q2T2", "gene_name": "trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2T2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9Q2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2T2" } ] } ] }, { "uniprot_ac": "A0A8M9Q3H8", "gene_name": "camk2b1", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q3H8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0A8M9Q3H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q3H8" } ] } ] }, { "uniprot_ac": "A0A8M9Q3N3", "gene_name": "LOC110440002", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q3N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q3N3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9Q3N3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q3N3" } ] } ] }, { "uniprot_ac": "A0A8M9Q3P0", "gene_name": "si:rp71-17i16.5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q3P0", "database": "UniProtKB", "url": 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] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9Q3P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q3P0" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "A0A8M9Q3P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q3P0" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "A0A8M9Q3P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q3P0" } ] }, { "ec_number": "2.7.1.154", "activity": "", "evidence": [ { "id": "A0A8M9Q3P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q3P0" } ] } ] }, { "uniprot_ac": "A0A8M9Q3R1", "gene_name": "cdk16", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q3R1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q3R1" } ] }, { "ec_number": "2.7.11.22", 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ADP + H(+).", "evidence": [ { "id": "A0A8M9QNM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QNM9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9QNM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QNM9" } ] } ] }, { "uniprot_ac": "A0A8N1Z395", "gene_name": "plk3", "activity": [ { "ec_number": "2.7.11.21", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8N1Z395", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N1Z395" } ] }, { "ec_number": "2.7.11.21", "activity": "", "evidence": [ { "id": "A0A8N1Z395", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N1Z395" } ] } ] }, { "uniprot_ac": "A0A8N7TBP6", "gene_name": "LOC568866", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8N7TBP6", "database": 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"https://www.uniprot.org/uniprotkb/A0A8N7TDX0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8N7TDX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TDX0" } ] } ] }, { "uniprot_ac": "A0A8N7TEF8", "gene_name": "atr", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8N7TEF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEF8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8N7TEF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEF8" } ] } ] }, { "uniprot_ac": "A0A8N7TFD0", "gene_name": "srpk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8N7TFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TFD0" } ] }, { "ec_number": 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"https://www.uniprot.org/uniprotkb/A0AA54FLJ5" } ] } ] }, { "uniprot_ac": "A0AA57WKX4", "gene_name": "mapk6", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AA57WKX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AA57WKX4" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "A0AA57WKX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AA57WKX4" } ] } ] }, { "uniprot_ac": "A0AB13A445", "gene_name": "pimr188", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB13A445", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A445" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB13A445", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A445" } ] } ] }, { "uniprot_ac": "A0AB13A8P5", "gene_name": "pimr187", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB13A8P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A8P5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB13A8P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A8P5" } ] } ] }, { "uniprot_ac": "A0AB13A8S4", "gene_name": "ern1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB13A8S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A8S4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB13A8S4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A8S4" } ] } ] }, { "uniprot_ac": "A0AB13A8Y8", "gene_name": "pimr186", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB13A8Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A8Y8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB13A8Y8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A8Y8" } ] } ] }, { "uniprot_ac": "A0AB13A9H1", "gene_name": "pimr193", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB13A9H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A9H1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB13A9H1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13A9H1" } ] } ] }, { "uniprot_ac": "A0AB13AAZ0", "gene_name": "pimr195", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB13AAZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAZ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB13AAZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB13AAZ0" } ] } ] }, { "uniprot_ac": "A0AB32T049", "gene_name": "pimr54", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T049" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T049", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T049" } ] } ] }, { "uniprot_ac": "A0AB32T3C9", "gene_name": "LOC110437995", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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"ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T714", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T714" } ] } ] }, { "uniprot_ac": "A0AB32T777", "gene_name": "LOC103909000", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T777", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T777" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T777", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T777" } ] } ] }, { "uniprot_ac": "A0AB32T7Q9", "gene_name": "LOC100149959", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T7Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T7Q9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T7Q9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T7Q9" } ] } ] }, { "uniprot_ac": "A0AB32T8E3", "gene_name": "LOC137487295", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T8E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8E3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T8E3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8E3" } ] } ] }, { "uniprot_ac": "A0AB32T8Q3", "gene_name": "LOC110437887", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T8Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8Q3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T8Q3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8Q3" } ] } ] }, { "uniprot_ac": "A0AB32T8U5", "gene_name": "ksr1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T8U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8U5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T8U5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8U5" } ] } ] }, { "uniprot_ac": "A0AB32T8X7", "gene_name": "LOC101884966", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T8X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8X7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T8X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8X7" } ] } ] }, { "uniprot_ac": "A0AB32T993", "gene_name": "pimr136", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T993", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T993" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T993", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T993" } ] } ] }, { "uniprot_ac": "A0AB32T9K7", "gene_name": "LOC137488956", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T9K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T9K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T9K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T9K7" } ] } ] }, { "uniprot_ac": "A0AB32T9P4", "gene_name": "LOC137488982", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T9P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T9P4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T9P4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T9P4" } ] } ] }, { "uniprot_ac": "A0AB32T9Z5", "gene_name": "LOC137487923", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T9Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T9Z5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T9Z5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T9Z5" } ] } ] }, { "uniprot_ac": "A0AB32TA36", "gene_name": "LOC137487941", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TA36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TA36" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TA36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TA36" } ] } ] }, { "uniprot_ac": "A0AB32TAC3", "gene_name": "LOC797378", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TAC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TAC3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TAC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TAC3" } ] } ] }, { "uniprot_ac": "A0AB32TAM5", "gene_name": "LOC137487769", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TAM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TAM5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TAM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TAM5" } ] } ] }, { "uniprot_ac": "A0AB32TB58", "gene_name": "rps6ka1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TB58" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TB58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TB58" } ] } ] }, { "uniprot_ac": "A0AB32TBV8", "gene_name": "LOC137487971", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TBV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TBV8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TBV8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TBV8" } ] } ] }, { "uniprot_ac": "A0AB32TCQ5", "gene_name": "LOC566974", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TCQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TCQ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TCQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TCQ5" } ] } ] }, { "uniprot_ac": "A0AB32TD43", "gene_name": "LOC137488987", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TD43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TD43" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TD43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TD43" } ] } ] }, { "uniprot_ac": "A0AB32TDK0", "gene_name": "pimr213", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TDK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TDK0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TDK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TDK0" } ] } ] }, { "uniprot_ac": "A0AB32TDW6", "gene_name": "pimr130", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TDW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TDW6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TDW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TDW6" } ] } ] }, { "uniprot_ac": "A0AB32TEJ5", "gene_name": "myo3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEJ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TEJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEJ5" } ] } ] }, { "uniprot_ac": "A0AB32TEW4", "gene_name": "LOC100150353", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEW4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TEW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEW4" } ] } ] }, { "uniprot_ac": "A0AB32TEY8", "gene_name": "camk2a", "activity": [ { "ec_number": "2.7.11.17", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TEY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEY8" } ] }, { "ec_number": "2.7.11.17", "activity": "", "evidence": [ { "id": "A0AB32TEY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEY8" } ] } ] }, { "uniprot_ac": "A0AB32TF84", "gene_name": "LOC137488983", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TF84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TF84" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TF84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TF84" } ] } ] }, { "uniprot_ac": "A0AB32TF89", "gene_name": "lrrk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TF89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TF89" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TF89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TF89" } ] } ] }, { "uniprot_ac": "A0AB32TFD0", "gene_name": "si:dkey-248f6.3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TFD0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TFD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TFD0" } ] } ] }, { "uniprot_ac": "A0AB32TFU8", "gene_name": "LOC108180740", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TFU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TFU8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TFU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TFU8" } ] } ] }, { "uniprot_ac": "A0AB32TGB4", "gene_name": "LOC137489340", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TGB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGB4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TGB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGB4" } ] } ] }, { "uniprot_ac": "A0AB32TGE2", "gene_name": "stk38b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TGE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGE2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TGE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGE2" } ] } ] }, { "uniprot_ac": "A0AB32TGI0", "gene_name": "LOC110438303", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TGI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGI0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TGI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGI0" } ] } ] }, { "uniprot_ac": "A0AB32TGR3", "gene_name": "pimr95", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TGR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGR3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TGR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGR3" } ] } ] }, { "uniprot_ac": "A0AB32TGR5", "gene_name": "LOC137489025", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TGR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGR5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TGR5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGR5" } ] } ] }, { "uniprot_ac": "A0AB32TGZ7", "gene_name": "LOC137489026", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TGZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TGZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGZ7" } ] } ] }, { "uniprot_ac": "A0AB32THX2", "gene_name": "dapk2b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32THX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32THX2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32THX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32THX2" } ] } ] }, { "uniprot_ac": "A0AB32TI35", "gene_name": "LOC137489393", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TI35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TI35" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TI35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TI35" } ] } ] }, { "uniprot_ac": "A0AB32TIC0", "gene_name": "prpf4bb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TIC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIC0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TIC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIC0" } ] } ] }, { "uniprot_ac": "A0AB32TIE4", "gene_name": "LOC108181140", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TIE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIE4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TIE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIE4" } ] } ] }, { "uniprot_ac": "A0AB32TIF8", "gene_name": "pimr148", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIF8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TIF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIF8" } ] } ] }, { "uniprot_ac": "A0AB32TIH5", "gene_name": "LOC561456", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TIH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIH5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TIH5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIH5" } ] } ] }, { "uniprot_ac": "A0AB32TIZ4", "gene_name": "LOC110438859", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TIZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIZ4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TIZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIZ4" } ] } ] }, { "uniprot_ac": "A0AB32TJ66", "gene_name": "LOC566482", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TJ66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJ66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TJ66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJ66" } ] } ] }, { "uniprot_ac": "A0AB32TJD1", "gene_name": "pimr190", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TJD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJD1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TJD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJD1" } ] } ] }, { "uniprot_ac": "A0AB32TJF7", "gene_name": "si:dkey-80c24.1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TJF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJF7" } ] } ] }, { "uniprot_ac": "A0AB32TJN7", "gene_name": "LOC137490613", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TJN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJN7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TJN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJN7" } ] } ] }, { "uniprot_ac": "A0AB32TJW3", "gene_name": "LOC566482", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TJW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJW3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TJW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJW3" } ] } ] }, { "uniprot_ac": "A0AB32TJY7", "gene_name": "LOC137488986", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJY7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJY7" } ] } ] }, { "uniprot_ac": "A0AB32TK67", "gene_name": "pimr123", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TK67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TK67" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TK67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TK67" } ] } ] }, { "uniprot_ac": "A0AB32TKD7", "gene_name": "LOC103909832", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TKD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TKD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TKD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TKD7" } ] } ] }, { "uniprot_ac": "A0AB32TKE5", "gene_name": "LOC137490288", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TKE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TKE5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TKE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TKE5" } ] } ] }, { "uniprot_ac": "A0AB32TLF7", "gene_name": "zmp:0000000653", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TLF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TLF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TLF7" } ] } ] }, { "uniprot_ac": "A0AB32TLV6", "gene_name": "LOC110438775", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TLV6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TLV6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TLV6" } ] } ] }, { "uniprot_ac": "A0AB32TM92", "gene_name": "LOC110438780", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TM92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TM92" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TM92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TM92" } ] } ] }, { "uniprot_ac": "A0AB32TMJ3", "gene_name": "LOC137488985", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TMJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TMJ3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TMJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TMJ3" } ] } ] }, { "uniprot_ac": "A0AB32TML5", "gene_name": "LOC137490286", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TML5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TML5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TML5" } ] } ] }, { "uniprot_ac": "A0AB32TN78", "gene_name": "pimr93", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TN78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TN78" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TN78", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TN78" } ] } ] }, { "uniprot_ac": "A0AB32TNZ5", "gene_name": "pimr201", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TNZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TNZ5" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TNZ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TNZ5" } ] } ] }, { "uniprot_ac": "A0AB32TP03", "gene_name": "LOC799924", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TP03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TP03" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TP03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TP03" } ] } ] }, { "uniprot_ac": "A0AB32TPU2", "gene_name": "pimr120", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TPU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TPU2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TPU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TPU2" } ] } ] }, { "uniprot_ac": "A0AB32TQA9", "gene_name": "LOC137495283", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TQA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQA9" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TQA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQA9" } ] } ] }, { "uniprot_ac": "A0AB32TR29", "gene_name": "LOC137495284", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TR29" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TR29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TR29" } ] } ] }, { "uniprot_ac": "A0AB32TS34", "gene_name": "LOC103910790", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TS34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TS34" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TS34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TS34" } ] } ] }, { "uniprot_ac": "A0AB32TS99", "gene_name": "LOC110438663", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TS99", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TS99" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TS99", "database": 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} ] }, { "uniprot_ac": "A0AB32TUB7", "gene_name": "LOC137494805", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TUB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUB7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TUB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUB7" } ] } ] }, { "uniprot_ac": "A0AB32TUE1", "gene_name": "LOC137495620", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TUE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUE1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TUE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUE1" } ] } ] }, { "uniprot_ac": "A0AB32TUI9", "gene_name": 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"url": "https://www.uniprot.org/uniprotkb/A0AB32TWL3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TWL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TWL3" } ] } ] }, { "uniprot_ac": "A0AB32TX22", "gene_name": "pimr50", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TX22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX22" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TX22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX22" } ] } ] }, { "uniprot_ac": "A0AB32TX27", "gene_name": "pimr127", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TX27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX27" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TX27", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX27" } ] } ] }, { "uniprot_ac": "A0AB32TX44", "gene_name": "LOC137496078", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TX44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX44" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TX44", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX44" } ] } ] }, { "uniprot_ac": "A0AB32TX96", "gene_name": "LOC101885707", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TX96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX96" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TX96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX96" } ] } ] }, { "uniprot_ac": "A0AB32TXG7", "gene_name": "LOC137496391", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TXG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TXG7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TXG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TXG7" } ] } ] }, { "uniprot_ac": "A0AB32TXK2", "gene_name": "wnk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TXK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TXK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TXK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TXK2" } ] } ] }, { "uniprot_ac": "A0AB32TYE8", "gene_name": "LOC110438839", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TYE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TYE8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TYE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TYE8" } ] } ] }, { "uniprot_ac": "A0AB32TYI1", "gene_name": "LOC103908726", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TYI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TYI1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TYI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TYI1" } ] } ] }, { "uniprot_ac": "A0AB32TYK2", "gene_name": "LOC137490188", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TYK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TYK2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TYK2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TYK2" } ] } ] }, { "uniprot_ac": "A0AB32TYY8", "gene_name": "LOC100334422", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TYY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TYY8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TYY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TYY8" } ] } ] }, { "uniprot_ac": "A0AB32TZ18", "gene_name": "LOC110439908", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TZ18" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TZ18", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TZ18" } ] } ] }, { "uniprot_ac": "A0AB32TZD7", "gene_name": "LOC137496553", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32TZD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TZD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32TZD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32TZD7" } ] } ] }, { "uniprot_ac": "A0AB32TZT6", "gene_name": "LOC103911713", "activity": [ { "ec_number": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32U0E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32U0E2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32U0E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32U0E2" } ] } ] }, { "uniprot_ac": "A0AB32U0G1", "gene_name": "si:ch211-122l14.7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32U0G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32U0G1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32U0G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32U0G1" } ] } ] }, { "uniprot_ac": "A0AB32U0S1", "gene_name": "map4k3a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", 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] }, { "uniprot_ac": "A0AC58GLD3", "gene_name": "LOC141376301", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58GLD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GLD3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58GLD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GLD3" } ] } ] }, { "uniprot_ac": "A0AC58GLP0", "gene_name": "LOC110440067", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58GLP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GLP0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58GLP0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GLP0" } ] } ] }, { "uniprot_ac": "A0AC58GLZ2", "gene_name": 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"activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58GN09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GN09" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58GN09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GN09" } ] } ] }, { "uniprot_ac": "A0AC58GN15", "gene_name": "LOC141376424", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58GN15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GN15" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58GN15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GN15" } ] } ] }, { "uniprot_ac": "A0AC58GN26", "gene_name": "LOC141375004", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58GN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GN26" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58GN26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GN26" } ] } ] }, { "uniprot_ac": "A0AC58GPM4", "gene_name": "prkacba", "activity": [ { "ec_number": "2.7.11.11", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58GPM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GPM4" } ] }, { "ec_number": "2.7.11.11", "activity": "", "evidence": [ { "id": "A0AC58GPM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GPM4" } ] } ] }, { "uniprot_ac": "A0AC58GRT4", "gene_name": "LOC141376527", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": 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"url": "https://www.uniprot.org/uniprotkb/A0AC58GRT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58GRT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRT7" } ] } ] }, { "uniprot_ac": "A0AC58GRU0", "gene_name": "LOC141376536", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58GRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRU0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58GRU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRU0" } ] } ] }, { "uniprot_ac": "A0AC58GRU1", "gene_name": "LOC110440124", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58GRU1", "database": "UniProtKB", "url": 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}, { "uniprot_ac": "A0AC58H3E1", "gene_name": "stk32c", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58H3E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58H3E1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58H3E1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58H3E1" } ] } ] }, { "uniprot_ac": "A0AC58H461", "gene_name": "pimr161", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58H461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58H461" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58H461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58H461" } ] } ] }, { "uniprot_ac": "A0AC58H477", "gene_name": "LOC141377131", 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}, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58H5R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58H5R5" } ] } ] }, { "uniprot_ac": "A0AC58H856", "gene_name": "LOC141374988", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58H856", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58H856" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58H856", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58H856" } ] } ] }, { "uniprot_ac": "A0AC58H861", "gene_name": "pimr210", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58H861", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58H861" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": 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}, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58HQU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQU8" } ] } ] }, { "uniprot_ac": "A0AC58HRF7", "gene_name": "dapk3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58HRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HRF7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58HRF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HRF7" } ] } ] }, { "uniprot_ac": "A0AC58HSD6", "gene_name": "trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58HSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HSD6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { 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"uniprot_ac": "A0ACD6B764", "gene_name": "prkd1", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ACD6B764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B764" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A0ACD6B764", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B764" } ] } ] }, { "uniprot_ac": "A0ACD6B780", "gene_name": "pimr144", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ACD6B780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B780" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ACD6B780", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B780" } ] } ] }, { "uniprot_ac": "A0ACD6B7H4", "gene_name": "hipk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ACD6B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B7H4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ACD6B7H4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B7H4" } ] } ] }, { "uniprot_ac": "A0ACD6B7I0", "gene_name": "nim1ka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ACD6B7I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B7I0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ACD6B7I0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B7I0" } ] } ] }, { "uniprot_ac": "A0ACD6B7L2", "gene_name": "gak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ACD6B7L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B7L2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ACD6B7L2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B7L2" } ] } ] }, { "uniprot_ac": "A0ACD6B7V3", "gene_name": "dyrk4", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ACD6B7V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B7V3" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "A0ACD6B7V3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B7V3" } ] } ] }, { "uniprot_ac": "A0ACD6B7Z7", "gene_name": "wnk4b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0ACD6B7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B7Z7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0ACD6B7Z7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0ACD6B7Z7" } ] } ] }, { "uniprot_ac": "A3KQ53", "gene_name": "si:ch211-195b13.1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A3KQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ53" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A3KQ53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ53" } ] } ] }, { "uniprot_ac": "A5WUM0", "gene_name": "prkaa1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5WUM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM0" } ] }, { "ec_number": "2.7.11.26", "activity": "L-seryl-[tau protein] + ATP = O-phospho-L-seryl-[tau protein] + ADP + H(+).", "evidence": [ { "id": "A5WUM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM0" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "A5WUM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM0" } ] }, { "ec_number": "2.7.11.26", "activity": "", "evidence": [ { "id": "A5WUM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM0" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "A5WUM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5WUM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM0" } ] } ] }, { "uniprot_ac": "A5WUT7", "gene_name": "riok2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A5WUT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUT7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A5WUT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUT7" } ] } ] }, { "uniprot_ac": "A7MBL8", "gene_name": "pkn2", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A7MBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBL8" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "A7MBL8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A7MBL8" } ] } ] }, { "uniprot_ac": "A8WIP6", "gene_name": "cdk20", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A8WIP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WIP6" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "A8WIP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WIP6" } ] } ] }, { "uniprot_ac": "B0S5E6", "gene_name": "pimr49", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "B0S5E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S5E6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B0S5E6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S5E6" } ] } ] }, { "uniprot_ac": "B0S6K0", "gene_name": "sik1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "B0S6K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6K0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B0S6K0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6K0" } ] } ] }, { "uniprot_ac": "B0S7G1", "gene_name": "pimr141", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "B0S7G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7G1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B0S7G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7G1" } ] } ] }, { "uniprot_ac": "B0S8I4", "gene_name": "lats2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "B0S8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S8I4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B0S8I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S8I4" } ] } ] }, { "uniprot_ac": "B0V1K6", "gene_name": "prpf4ba", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "B0V1K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V1K6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B0V1K6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V1K6" } ] } ] }, { "uniprot_ac": "B0V360", "gene_name": "mapk4", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "B0V360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V360" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "B0V360", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V360" } ] } ] }, { "uniprot_ac": "B8A4S3", "gene_name": "slkb", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "B8A4S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4S3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "B8A4S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4S3" } ] } ] }, { "uniprot_ac": "C5J7W8", "gene_name": "smg1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "C5J7W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C5J7W8" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "C5J7W8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/C5J7W8" } ] } ] }, { "uniprot_ac": "E7EXS2", "gene_name": "tnni3k", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7EXS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXS2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7EXS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXS2" } ] } ] }, { "uniprot_ac": "E7EZL0", "gene_name": "lmtk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7EZL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZL0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7EZL0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZL0" } ] } ] }, { "uniprot_ac": "E7F164", "gene_name": "rps6ka2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F164", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F164" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7F164", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F164" } ] } ] }, { "uniprot_ac": "E7F1A1", "gene_name": "dapk2a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F1A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1A1" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7F1A1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1A1" } ] } ] }, { "uniprot_ac": "E7F1L8", "gene_name": "nlk2", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F1L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1L8" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E7F1L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1L8" } ] } ] }, { "uniprot_ac": "E7F292", "gene_name": "mapk13", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F292", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F292" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E7F292", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F292" } ] } ] }, { "uniprot_ac": "E7F2L3", "gene_name": "map3k5", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F2L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2L3" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E7F2L3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2L3" } ] } ] }, { "uniprot_ac": "E7F368", "gene_name": "prkcea", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F368" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E7F368", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F368" } ] } ] }, { "uniprot_ac": "E7F378", "gene_name": "sik2b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F378" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7F378", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F378" } ] } ] }, { "uniprot_ac": "E7F705", "gene_name": "unm_sa1261", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F705", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F705" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7F705", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F705" } ] } ] }, { "uniprot_ac": "E7F723", "gene_name": "mast2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F723", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F723" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7F723", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F723" } ] } ] }, { "uniprot_ac": "E7F7I3", "gene_name": "pkn3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F7I3" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E7F7I3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F7I3" } ] } ] }, { "uniprot_ac": "E7F802", "gene_name": "sbk1", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F802", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F802" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7F802", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F802" } ] } ] }, { "uniprot_ac": "E7F9C4", "gene_name": "prkaa2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ] }, { "ec_number": "2.7.11.31", "activity": "L-seryl-[acetyl-CoA carboxylase] + ATP = O-phospho-L-seryl-[acetyl-CoA carboxylase] + ADP + H(+).", "evidence": [ { "id": "E7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ] }, { "ec_number": "2.7.11.31", "activity": "", "evidence": [ { "id": "E7F9C4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F9C4" } ] } ] }, { "uniprot_ac": "E7F9R5", "gene_name": "cdk18", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F9R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F9R5" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "E7F9R5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F9R5" } ] } ] }, { "uniprot_ac": "E7F9Z2", "gene_name": "prkd3", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7F9Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F9Z2" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "E7F9Z2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F9Z2" } ] } ] }, { "uniprot_ac": "E7FB10", "gene_name": "pim3", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7FB10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FB10" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7FB10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FB10" } ] } ] }, { "uniprot_ac": "E7FB16", "gene_name": "limk1b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7FB16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FB16" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7FB16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FB16" } ] } ] }, { "uniprot_ac": "E7FE05", "gene_name": "rps6ka5", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7FE05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FE05" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7FE05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FE05" } ] } ] }, { "uniprot_ac": "E7FE66", "gene_name": "ttbk2a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7FE66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FE66" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "E7FE66", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FE66" } ] } ] }, { "uniprot_ac": "E7FEW6", "gene_name": "tesk1b", "activity": [ { "ec_number": "2.7.12.1", "activity": "L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7FEW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FEW6" } ] }, { "ec_number": "2.7.12.1", "activity": "", "evidence": [ { "id": "E7FEW6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FEW6" } ] } ] }, { "uniprot_ac": "E7FEY1", "gene_name": "map3k14a", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E7FEY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FEY1" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "E7FEY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FEY1" } ] } ] }, { "uniprot_ac": "E9QE29", "gene_name": "mapk9", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "E9QE29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QE29" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "E9QE29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QE29" } ] } ] }, { "uniprot_ac": "F1Q5H3", "gene_name": "slka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1Q5H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5H3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1Q5H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5H3" } ] } ] }, { "uniprot_ac": "F1Q5J2", "gene_name": "map3k10", "activity": [ { "ec_number": "2.7.11.25", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1Q5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5J2" } ] }, { "ec_number": "2.7.11.25", "activity": "", "evidence": [ { "id": "F1Q5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5J2" } ] } ] }, { "uniprot_ac": "F1QAD7", "gene_name": "pik3ca", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1QAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QAD7" } ] }, { "ec_number": "2.7.1.153", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-4,5-bisphosphate) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3,4,5-trisphosphate) + ADP + H(+).", "evidence": [ { "id": "F1QAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QAD7" } ] }, { "ec_number": "2.7.1.137", "activity": "a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol) + ATP = a 1,2-diacyl-sn-glycero-3-phospho-(1D-myo-inositol-3-phosphate) + ADP + H(+).", "evidence": [ { "id": "F1QAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QAD7" } ] }, { "ec_number": "2.7.1.153", "activity": "", "evidence": [ { "id": "F1QAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QAD7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1QAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QAD7" } ] }, { "ec_number": "2.7.1.137", "activity": "", "evidence": [ { "id": "F1QAD7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QAD7" } ] } ] }, { "uniprot_ac": "F1QB90", "gene_name": "tp53rk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1QB90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QB90" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1QB90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QB90" } ] } ] }, { "uniprot_ac": "F1QGZ6", "gene_name": "melk", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1QGZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QGZ6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1QGZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QGZ6" } ] } ] }, { "uniprot_ac": "F1QJB6", "gene_name": "atm", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1QJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1QJB6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QJB6" } ] } ] }, { "uniprot_ac": "F1QM17", "gene_name": "snrka", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1QM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QM17" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1QM17", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QM17" } ] } ] }, { "uniprot_ac": "F1QU13", "gene_name": "alpk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1QU13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QU13" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1QU13", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QU13" } ] } ] }, { "uniprot_ac": "F1QUT2", "gene_name": "mak", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1QUT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QUT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1QUT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QUT2" } ] } ] }, { "uniprot_ac": "F1QVT2", "gene_name": "si:dkey-192d15.2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1QVT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QVT2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1QVT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QVT2" } ] } ] }, { "uniprot_ac": "F1QZR2", "gene_name": "pak4", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1QZR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QZR2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1QZR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QZR2" } ] } ] }, { "uniprot_ac": "F1R343", "gene_name": "nuak1a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1R343", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R343" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1R343", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R343" } ] } ] }, { "uniprot_ac": "F1R6Y1", "gene_name": "cdk12", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1R6Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R6Y1" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "F1R6Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R6Y1" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "F1R6Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R6Y1" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "F1R6Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R6Y1" } ] } ] }, { "uniprot_ac": "F1RC23", "gene_name": "ttbk2b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "F1RC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RC23" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "F1RC23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1RC23" } ] } ] }, { "uniprot_ac": "I3IT74", "gene_name": "cdk6", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "I3IT74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3IT74" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "I3IT74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/I3IT74" } ] } ] }, { "uniprot_ac": "O42376", "gene_name": "mapk12", "activity": [ { "ec_number": "2.7.11.24", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "O42376", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42376" } ] }, { "ec_number": "2.7.11.24", "activity": "", "evidence": [ { "id": "O42376", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/O42376" } ] } ] }, { "uniprot_ac": "Q1ECX4", "gene_name": "tlk2", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1ECX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1ECX4" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1ECX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1ECX4" } ] } ] }, { "uniprot_ac": "Q1LUA6", "gene_name": "trio", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1LUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LUA6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1LUA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LUA6" } ] } ] }, { "uniprot_ac": "Q1LUZ7", "gene_name": "hipk3b", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1LUZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LUZ7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1LUZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LUZ7" } ] } ] }, { "uniprot_ac": "Q1LYG2", "gene_name": "braf", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1LYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LYG2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q1LYG2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1LYG2" } ] } ] }, { "uniprot_ac": "Q1RLU9", "gene_name": "cdk15", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q1RLU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RLU9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q1RLU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1RLU9" } ] } ] }, { "uniprot_ac": "Q32PP3", "gene_name": "pdik1l", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q32PP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q32PP3" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q32PP3", "database": "UniProtKB", "url": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5RHX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RHX9" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q5RHX9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5RHX9" } ] } ] }, { "uniprot_ac": "Q5SPF6", "gene_name": "pimr109", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5SPF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SPF6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q5SPF6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5SPF6" } ] } ] }, { "uniprot_ac": "Q5TZ37", "gene_name": "cdc42bpab", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q5TZ37", "database": 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O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6P3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6P3K7" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6P3K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6P3K7" } ] } ] }, { "uniprot_ac": "Q6PFQ0", "gene_name": "rps6ka6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q6PFQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6PFQ0" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "Q6PFQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6PFQ0" } ] } ] }, { "uniprot_ac": "Q7SXE8", "gene_name": "cdk9", "activity": [ { "ec_number": "2.7.11.22", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7SXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7SXE8" } ] }, { "ec_number": "2.7.11.23", "activity": "[DNA-directed RNA polymerase] + ATP = phospho-[DNA-directed RNA polymerase] + ADP + H(+).", "evidence": [ { "id": "Q7SXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7SXE8" } ] }, { "ec_number": "2.7.11.23", "activity": "", "evidence": [ { "id": "Q7SXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7SXE8" } ] }, { "ec_number": "2.7.11.22", "activity": "", "evidence": [ { "id": "Q7SXE8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7SXE8" } ] } ] }, { "uniprot_ac": "Q7SY24", "gene_name": "prkcbb", "activity": [ { "ec_number": "2.7.11.13", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "Q7SY24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7SY24" } ] }, { "ec_number": "2.7.11.13", "activity": "", "evidence": [ { "id": "Q7SY24", "database": 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"function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021324748.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324748", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324748" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD90", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD90" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "kcnk12l", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD90", "locus": {} } ], "crossref": [ { "id": "A0A8M9PD90", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PD90", "database": "AlphaFoldDB", "categories": [] }, { "id": "564796", "url": "https://www.ncbi.nlm.nih.gov/gene/564796", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003280", "database": 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K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AB32T5S6-1", "A0AC58II33-1" ], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0AB32T5S6", "gene_name": "kcnk4a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T5S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T5S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T5S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T5S6" } ] } ] }, { "uniprot_ac": "A0AC58II33", "gene_name": "pycr1a", "activity": [ { "ec_number": "1.5.1.2", "activity": "L-proline + NAD(+) = (S)-1-pyrroline-5-carboxylate + NADH + 2 H(+).", "evidence": [ { "id": "A0AC58II33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58II33" } ] }, { "ec_number": "1.5.1.2", "activity": "", "evidence": [ { "id": "A0AC58II33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58II33" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PD90", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD90" }, { "id": "PF07885", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07885" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Potassium channel", "eco_id": "ECO_0000259", "start_pos": 115, "end_pos": 172, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 380, "end_pos": 382 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PD97-1", "uniprot_ac": "A0A8M9PD97", "uniprot_id": "A0A8M9PD97_DANRE", "mass": { "chemical_mass": 334991.0, "monoisotopic_mass": 334991.0 }, "refseq": { "ac": "XP_021322449", "name": "uncharacterized protein si:dkeyp-106c3.1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322449" }, "gene_names": [ { "name": "si:dkeyp-106c3.1", "type": "recommended", "evidence": [ { "id": "A0A8M9PD97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97" } ] }, { "name": "si:dkeyp-106c3.1", "type": "synonym", "evidence": [ { "id": "XP_021322449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322449" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkeyp-106c3.1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PD97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkeyp-106c3.1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322449", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322449" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322449" } ] } ], "disease": [ { "disease_id": "DOID:1682", "recommended_name": { "id": "DOID:1682", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1682", "name": "congenital heart disease", "description": "A physical disorder that is characterized by problems with the heart's structure that are present at birth." }, "synonyms": [ { "id": "DOID:1682", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1682", "name": "Congenital Heart Defects", "description": "" }, { "id": "DOID:1682", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1682", "name": "Congenital anomaly of heart", "description": "" }, { "id": "DOID:1682", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1682", "name": "Heart Malformation", "description": "" }, { "id": "DOID:1682", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1682", "name": "congenital heart defect", "description": "" }, { "id": "DOID:1682", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1682", "name": "heart defect", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1682", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1682" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkeyp-106c3.1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050411-73", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050411-73", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "558820", "url": "https://www.ncbi.nlm.nih.gov/gene/558820", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015817", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015817", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015819", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015819", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558820", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558820", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PD97", "url": "https://www.orthodb.org/?gene=A0A8M9PD97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37860", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37860", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37860:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37860:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF09172", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09172", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21013", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21013", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322449", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322449", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PD97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PD97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HAT8", "url": "https://www.uniprot.org/uniprotkb/A0AC58HAT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HAT8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HAT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HAU0", "url": "https://www.uniprot.org/uniprotkb/A0AC58HAU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HAU0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HAU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HAU4", "url": "https://www.uniprot.org/uniprotkb/A0AC58HAU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HAU4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HAU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HAV3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HAV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HAV3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HAV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HAV5", "url": "https://www.uniprot.org/uniprotkb/A0AC58HAV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HAV5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HAV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HAV7", "url": "https://www.uniprot.org/uniprotkb/A0AC58HAV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HAV7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HAV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050411-73", "url": "https://zfin.org/ZDB-GENE-050411-73", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAMSRVCLLLQDLGLIIMLIFFSVDCQKLQQGQLCKPACPDVQKGQRHTYRYSTTISSTWKGSSSGGSQLALDCVIDINVRPGCPDMMLKLRNIQIKQSSSKRDNSVQRLKNMRESLEKNPLRFSLEGGKVTMFCPQEAEQVWTLNIKRSILSMIQTSHSGRARETVRETDVYGTCTSSYERRGPSLVKIRNLQLCLSDRIDQFWRSSVPLKEDMTVSAGLTCVQLYDDTVLKKVNCTETVSLVPLPGLLEVTETKTVSSLTLLRTLDVIPMDLAQNTGYLSSIVFEAEGQSSGRHAGPSVQEVSNIVRRLCAHLMDQQQQSELLLNLVLQLRALSSRQLRDLWHEASFKCRDDWQPLVDALSACGTENCILVNADLILNKEVDQEHILPLISFASHPTPSIISHLSALLQIPLIRPKVLLVVSSLVHRFCQQSPCSEISEVQQFVHLLKLSLEAGCQVDDHLKITELLHVLKAVENAGAAVSDLIPTLSRCVQNHSVPLELQLAAIRAFRRIPCHQDRKVLAQVFQRQQENVEVRIAAYQQLMHCPNQEIFTLVKTTLSNEKSSQVGSFVWSHLFNIQKTEDPLKKYLMESLPDDIISRDFEAEPWKYSSHMDYTVDTGVAAANVEGALVFSPQSFLPSYAMANLTVFILGRAFNLLEISLRMENLEPLLKTVFEQQPLASADHSGPSAQADSVKKKERNSNSDGCQSATFSSMRTKFTEQRKKDRTLHCWINVKMFGNDMTFMTCDDLHSYQRKLSLSTAGVVVKLLKGQEIKLSQKPVVLAEELVLPSLSGLPMRLSINMSALFSLRLKGISNYKNWSHFSLAGYIKPSALVGISVRAGVDGAIGRVGLEWVTQLKTSTSLDGAVYLHHGQNLKLVLNTPEDVMDILTFNSRVFRVSGDLKDELVVTRNLKEKNTCTPKTWSKMVGWQLCSDLTYPLTLMGKSFPPLGPVIFTLRLQKLDKGLNQYLLEAAYTFVSQRHFWMPLEATLLLFIGTPQSTIHRDVSLDVNLTPKRLILKITHPLKAILIQAQLEEINNQRSGRIELLIDNIHHYFIKGLLETVNLASEMRTHFHLDAKVVADGHPFSLSVNTTHARSRKFVIQALLKNVFNKDASFSVQLERSLEDGRRHYSIDAGFLLPSAVSLRGLGLLKQRGSEWSSAVRVRYGVKEDLEKMQECHMTQNLHSESDSIQTYRVTAAHELHCSQFINLNHKILFKHERSPVHVQSSLDISYGKQWNQSSNKHRILFNQSLRNQSGPDLTSYAVELSLRLLDRGQNYRTQLLHNNFKTQKSESSTHLKINYNNQMPLIAGVHWKDVSTKTSLQKWEGSFNMDTPWLYVYAAQKLAQPQRGITQFSSEVTTRKLVNIRGVTLEGFYKDRGKERQGQLHLFTPTFSYVKVGGWSVLGKRGVKASYSISTAWTPALHGQISVGNGKQVKTLEMSAGYGKQDLNISAVLSTLDKKLKKRLLMMTMTLADLKNPYAELQIEGAIEETRKDKRVYQKRWKLNFRQPFKFLPQSLILQETFTSDLHHKVYTLESKVLVHGNRKAIHVLTLGFQPQQPYMCSSLVQSFSTERIPQDSKICFTVQNNQNVHEIHVRLWAGNEERLEAFGQVQFHDPATFQQGITIKANLSQLIKMDFPLNVSLNIEALKSHRSKSDFEYHSEGQICIDNRIYQANTAMIVSHFGNISSSISLQADEKNSTIHLILENKAGKGSNALSIYADFHQTLLAGVTPEGHIHLYANCSSERVFLQCRVKKEDETFSAHLTGSLPHDKLHLSLSGDVVNSIQDLSALPNSVSMVGVLTQSNGLTEGELTVVVDDAVYGLEVTQQSGEDLRALLCVVIMEESLCVNISSIVTQHGCRSYTQLSHSFPWLHFAAGLPFHSSAGVFMNWNNSSVCAQLELHADARGLSATLEQSSQSQVNYTEGINTGPLLAICSEQDQKDTLKVGVRANLQSSTFSFDLQGHHNISSTGLMLNISHNTPALHPYLPSDFYSKSQLRRSQSSAKCTAELLVGVSSLAFDAEILSANSGFKQALVFNHSIPQLHLLPRNLTVRTLYGGKRGSHIFTHRAQWDNQDSTHTTSSYDYTQFQQSYPELTGTALGWGLDLKVENDSQRKLGDLNMDWSLFGSREELKVQGSWALVSRQMDSSEQKQAFVSTLTQFHIHALSHGLTNRNEGISQAHISTSHRKPVNVSVTVSEHWHGDSSRGQACVFILPGQMQTLLPLVEMEGCVAVAQDGKSYSQNTELKWKDKRITQSMKYQCGVKGMHTLLVELGAQNVSPSPCPSHSLLTQIHTNLRDHLEHHVQIGLCPPQPALIWSGSHRVNSGKEMLLTHSRVSVSGHPQHSTFTLSLRNTSSSQRSNYSLLTEWQVGNWSVELASSSMVSGRSVAVQVHAKLDRSELLWLQGALGKRCLRAAAGYHTETSDDLRLLLCSEGHHWFTLEAQRGGAGIENETLALISVGAANQSLLFGAKGCGDCLWAAEARLQQLGSRIRNKLFDRFQRLQHLLLTFRRQAGDSVFLLELSAWPLSLTQRAETLLERSAVLWKAWTTGPLRHTLTHSLPNALQLLHLMSQQVQQELRKPLATLAGAYHDVTGERLDAVWQQGVQMWTRELTELLPSMLHDPHLRTPSLTALHAAVFAMDMVSQQTFQWMEARLAAMLVGVRRQLALIYKFSKSEGELMLRVPLPEGPWLMVKDAGMTEVLLEEFVLKPLLALNSMSPTAELYRLKRRIMDSPANYQAFLVADVYLVSFDGHLFQLPAACDFILAADVTKNTFSIALKSGRFKRRSLVMQMQNTTTAIHANGEVEVNCHVTHVPYTNPEVAVRKDVNFIEVSNGRGLWVSCDHHLEVCSVILDGWLHGVSSGLLGTNDNEGSNEQLLPDGSHTSGLLQFAHSWQVDSECVSRKADVCQNATADSLSCTFLFSSTNSPLSPCFRVVDPVQFAMECEILECVRDERADVPKPAYCSLASAYIHVCHRNYVPLELPVQCV", "length": 2992, "header": "tr|A0A8M9PD97-1|A0A8M9PD97_DANRE Isoform 1 of Uncharacterized protein si:dkeyp-106c3.1 isoform X1 OS=Danio rerio OX=7955 GN=si:dkeyp-106c3.1 PE=4 SV=1 CANONICAL=A0A8M9PD97-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PD97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97/entry#A0A8M9PD97-1", "sequence": { "sequence": "MAMSRVCLLLQDLGLIIMLIFFSVDCQKLQQGQLCKPACPDVQKGQRHTYRYSTTISSTWKGSSSGGSQLALDCVIDINVRPGCPDMMLKLRNIQIKQSSSKRDNSVQRLKNMRESLEKNPLRFSLEGGKVTMFCPQEAEQVWTLNIKRSILSMIQTSHSGRARETVRETDVYGTCTSSYERRGPSLVKIRNLQLCLSDRIDQFWRSSVPLKEDMTVSAGLTCVQLYDDTVLKKVNCTETVSLVPLPGLLEVTETKTVSSLTLLRTLDVIPMDLAQNTGYLSSIVFEAEGQSSGRHAGPSVQEVSNIVRRLCAHLMDQQQQSELLLNLVLQLRALSSRQLRDLWHEASFKCRDDWQPLVDALSACGTENCILVNADLILNKEVDQEHILPLISFASHPTPSIISHLSALLQIPLIRPKVLLVVSSLVHRFCQQSPCSEISEVQQFVHLLKLSLEAGCQVDDHLKITELLHVLKAVENAGAAVSDLIPTLSRCVQNHSVPLELQLAAIRAFRRIPCHQDRKVLAQVFQRQQENVEVRIAAYQQLMHCPNQEIFTLVKTTLSNEKSSQVGSFVWSHLFNIQKTEDPLKKYLMESLPDDIISRDFEAEPWKYSSHMDYTVDTGVAAANVEGALVFSPQSFLPSYAMANLTVFILGRAFNLLEISLRMENLEPLLKTVFEQQPLASADHSGPSAQADSVKKKERNSNSDGCQSATFSSMRTKFTEQRKKDRTLHCWINVKMFGNDMTFMTCDDLHSYQRKLSLSTAGVVVKLLKGQEIKLSQKPVVLAEELVLPSLSGLPMRLSINMSALFSLRLKGISNYKNWSHFSLAGYIKPSALVGISVRAGVDGAIGRVGLEWVTQLKTSTSLDGAVYLHHGQNLKLVLNTPEDVMDILTFNSRVFRVSGDLKDELVVTRNLKEKNTCTPKTWSKMVGWQLCSDLTYPLTLMGKSFPPLGPVIFTLRLQKLDKGLNQYLLEAAYTFVSQRHFWMPLEATLLLFIGTPQSTIHRDVSLDVNLTPKRLILKITHPLKAILIQAQLEEINNQRSGRIELLIDNIHHYFIKGLLETVNLASEMRTHFHLDAKVVADGHPFSLSVNTTHARSRKFVIQALLKNVFNKDASFSVQLERSLEDGRRHYSIDAGFLLPSAVSLRGLGLLKQRGSEWSSAVRVRYGVKEDLEKMQECHMTQNLHSESDSIQTYRVTAAHELHCSQFINLNHKILFKHERSPVHVQSSLDISYGKQWNQSSNKHRILFNQSLRNQSGPDLTSYAVELSLRLLDRGQNYRTQLLHNNFKTQKSESSTHLKINYNNQMPLIAGVHWKDVSTKTSLQKWEGSFNMDTPWLYVYAAQKLAQPQRGITQFSSEVTTRKLVNIRGVTLEGFYKDRGKERQGQLHLFTPTFSYVKVGGWSVLGKRGVKASYSISTAWTPALHGQISVGNGKQVKTLEMSAGYGKQDLNISAVLSTLDKKLKKRLLMMTMTLADLKNPYAELQIEGAIEETRKDKRVYQKRWKLNFRQPFKFLPQSLILQETFTSDLHHKVYTLESKVLVHGNRKAIHVLTLGFQPQQPYMCSSLVQSFSTERIPQDSKICFTVQNNQNVHEIHVRLWAGNEERLEAFGQVQFHDPATFQQGITIKANLSQLIKMDFPLNVSLNIEALKSHRSKSDFEYHSEGQICIDNRIYQANTAMIVSHFGNISSSISLQADEKNSTIHLILENKAGKGSNALSIYADFHQTLLAGVTPEGHIHLYANCSSERVFLQCRVKKEDETFSAHLTGSLPHDKLHLSLSGDVVNSIQDLSALPNSVSMVGVLTQSNGLTEGELTVVVDDAVYGLEVTQQSGEDLRALLCVVIMEESLCVNISSIVTQHGCRSYTQLSHSFPWLHFAAGLPFHSSAGVFMNWNNSSVCAQLELHADARGLSATLEQSSQSQVNYTEGINTGPLLAICSEQDQKDTLKVGVRANLQSSTFSFDLQGHHNISSTGLMLNISHNTPALHPYLPSDFYSKSQLRRSQSSAKCTAELLVGVSSLAFDAEILSANSGFKQALVFNHSIPQLHLLPRNLTVRTLYGGKRGSHIFTHRAQWDNQDSTHTTSSYDYTQFQQSYPELTGTALGWGLDLKVENDSQRKLGDLNMDWSLFGSREELKVQGSWALVSRQMDSSEQKQAFVSTLTQFHIHALSHGLTNRNEGISQAHISTSHRKPVNVSVTVSEHWHGDSSRGQACVFILPGQMQTLLPLVEMEGCVAVAQDGKSYSQNTELKWKDKRITQSMKYQCGVKGMHTLLVELGAQNVSPSPCPSHSLLTQIHTNLRDHLEHHVQIGLCPPQPALIWSGSHRVNSGKEMLLTHSRVSVSGHPQHSTFTLSLRNTSSSQRSNYSLLTEWQVGNWSVELASSSMVSGRSVAVQVHAKLDRSELLWLQGALGKRCLRAAAGYHTETSDDLRLLLCSEGHHWFTLEAQRGGAGIENETLALISVGAANQSLLFGAKGCGDCLWAAEARLQQLGSRIRNKLFDRFQRLQHLLLTFRRQAGDSVFLLELSAWPLSLTQRAETLLERSAVLWKAWTTGPLRHTLTHSLPNALQLLHLMSQQVQQELRKPLATLAGAYHDVTGERLDAVWQQGVQMWTRELTELLPSMLHDPHLRTPSLTALHAAVFAMDMVSQQTFQWMEARLAAMLVGVRRQLALIYKFSKSEGELMLRVPLPEGPWLMVKDAGMTEVLLEEFVLKPLLALNSMSPTAELYRLKRRIMDSPANYQAFLVADVYLVSFDGHLFQLPAACDFILAADVTKNTFSIALKSGRFKRRSLVMQMQNTTTAIHANGEVEVNCHVTHVPYTNPEVAVRKDVNFIEVSNGRGLWVSCDHHLEVCSVILDGWLHGVSSGLLGTNDNEGSNEQLLPDGSHTSGLLQFAHSWQVDSECVSRKADVCQNATADSLSCTFLFSSTNSPLSPCFRVVDPVQFAMECEILECVRDERADVPKPAYCSLASAYIHVCHRNYVPLELPVQCV", "length": 2992, "header": "tr|A0A8M9PD97-1|A0A8M9PD97_DANRE Isoform 1 of Uncharacterized protein si:dkeyp-106c3.1 isoform X1 OS=Danio rerio OX=7955 GN=si:dkeyp-106c3.1 PE=4 SV=1 CANONICAL=A0A8M9PD97-1" }, "locus": {} }, { "isoform_ac": "A0AC58HAT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97/entry#A0AC58HAT8-1", "sequence": { "sequence": "MAMSRVCLLLQDLGLIIMLIFFSVDCQKLQQGQLCKPACPDVQKGQRHTYRYSTTISSTWKGSSSGGSQLALDCVIDINVRPGCPDMMLKLRNIQIKQSSSKRDNSVQRLKNMRESLEKNPLRFSLEGGKVTMFCPQEAEQVWTLNIKRSILSMIQTSHSGRARETVRETDVYGTCTSSYERRGPSLVKIRNLQLCLSDRIDQFWRSSVPLKEDMTVSAGLTCVQLYDDTVLKKVNCTETVSLVPLPGLLEVTETKTVSSLTLLRTLDVIPMDLAQNTGYLSSIVFEAEGQSSGRHAGPSVQEVSNIVRRLCAHLMDQQQQSELLLNLVLQLRALSSRQLRDLWHEASFKCRDDWQPLVDALSACGTENCILVNADLILNKEVDQEHILPLISFASHPTPSIISHLSALLQIPLIRPKVLLVVSSLVHRFCQQSPCSEISEVQQFVHLLKLSLEAGCQVDDHLKITELLHVLKAVENAGAAVSDLIPTLSRCVQNHSVPLELQLAAIRAFRRIPCHQDRKVLAQVFQRQQENVEVRIAAYQQLMHCPNQEIFTLVKTTLSNEKSSQVGSFVWSHLFNIQKTEDPLKKYLMESLPDDIISRDFEAEPWKYSSHMDYTVDTGVAAANVEGALVFSPQSFLPSYAMANLTVFILGRAFNLLEISLRMENLEPLLKTVFEQQPLASADHSGPSAQADSVKKKERNSNSDGCQSATFSSMRTKFTEQRKKDRTLHCWINVKMFGNDMTFMTCDDLHSYQRKLSLSTAGVVVKLLKGQEIKLSQKPVVLAEELVLPSLSGLPMRLSINMSALFSLRLKGISNYKNWSHFSLAGYIKPSALVGISVRAGVDGAIGRVGLEWVTQLKTSTSLDGAVYLHHGQNLKLVLNTPEDVMDILTFNSRVFRVSGDLKDELVVTRNLKEKNTCTPKTWSKMVGWQLCSDLTYPLTLMGKSFPPLGPVIFTLRLQKLDKGLNQYLLEAAYTFVSQRHFWMPLEATLLLFIGTPQSTIHRDVSLDVNLTPKRLILKITHPLKAILIQAQLEEINNQRSGRIELLIDNIHHYFIKGLLETVNLASEMRTHFHLDAKVVADGHPFSLSVNTTHARSRKFVIQALLKNVFNKDASFSVQLERSLEDGRRHYSIDAGFLLPSAVSLRGLGLLKQRGSEWSSAVRVRYGVKDLEKMQECHMTQNLHSESDSIQTYRVTAAHELHCSQFINLNHKILFKHERSPVHVQSSLDISYGKQWNQSSNKHRILFNQSLRNQSGPDLTSYAVELSLRLLDRGQNYRTQLLHNNFKTQKSESSTHLKINYNNQMPLIAGVHWKDVSTKTSLQKWEGSFNMDTPWLYVYAAQKLAQPQRGITQFSSEVTTRKLVNIRGVTLEGFYKDRGKERQGQLHLFTPTFSYVKVGGWSVLGKRGVKASYSISTAWTPALHGQISVGNGKQVKTLEMSAGYGKQDLNISAVLSTLDKKLKKRLLMMTMTLADLKNPYAELQIEGAIEETRKDKRVYQKRWKLNFRQPFKFLPQSLILQETFTSDLHHKVYTLESKVLVHGNRKAIHVLTLGFQPQQPYMCSSLVQSFSTERIPQDSKICFTVQNNQNVHEIHVRLWAGNEERLEAFGQVQFHDPATFQQGITIKANLSQLIKMDFPLNVSLNIEALKSHRSKSDFEYHSEGQICIDNRIYQANTAMIVSHFGNISSSISLQADEKNSTIHLILENKAGKGSNALSIYADFHQTLLAGVTPEGHIHLYANCSSERVFLQCRVKKEDETFSAHLTGSLPHDKLHLSLSGDVVNSIQDLSALPNSVSMVGVLTQSNGLTEGELTVVVDDAVYGLEVTQQSGEDLRALLCVVIMEESLCVNISSIVTQHGCRSYTQLSHSFPWLHFAAGLPFHSSAGVFMNWNNSSVCAQLELHADARGLSATLEQSSQSQVNYTEGINTGPLLAICSEQDQKDTLKVGVRANLQSSTFSFDLQGHHNISSTGLMLNISHNTPALHPYLPSDFYSKSQLRRSQSSAKCTAELLVGVSSLAFDAEILSANSGFKQALVFNHSIPQLHLLPRNLTVRTLYGGKRGSHIFTHRAQWDNQDSTHTTSSYDYTQFQQSYPELTGTALGWGLDLKVENDSQRKLGDLNMDWSLFGSREELKVQGSWALVSRQMDSSEQKQAFVSTLTQFHIHALSHGLTNRNEGISQAHISTSHRKPVNVSVTVSEHWHGDSSRGQACVFILPGQMQTLLPLVEMEGCVAVAQDGKSYSQNTELKWKDKRITQSMKYQCGVKGMHTLLVELGAQNVSPSPCPSHSLLTQIHTNLRDHLEHHVQIGLCPPQPALIWSGSHRVNSGKEMLLTHSRVSVSGHPQHSTFTLSLRNTSSSQRSNYSLLTEWQVGNWSVELASSSMVSGRSVAVQVHAKLDRSELLWLQGALGKRCLRAAAGYHTETSDDLRLLLCSEGHHWFTLEAQRGGAGIENETLALISVGAANQSLLFGAKGCGDCLWAAEARLQQLGSRIRNKLFDRFQRLQHLLLTFRRQAGDSVFLLELSAWPLSLTQRAETLLERSAVLWKAWTTGPLRHTLTHSLPNALQLLHLMSQQVQQELRKPLATLAGAYHDVTGERLDAVWQQGVQMWTRELTELLPSMLHDPHLRTPSLTALHAAVFAMDMVSQQTFQWMEARLAAMLVGVRRQLALIYKFSKSEGELMLRVPLPEGPWLMVKDAGMTEVLLEEFVLKPLLALNSMSPTAELYRLKRRIMDSPANYQAFLVADVYLVSFDGHLFQLPAACDFILAADVTKNTFSIALKSGRFKRRSLVMQMQNTTTAIHANGEVEVNCHVTHVPYTNPEVAVRKDVNFIEVSNGRGLWVSCDHHLEVCSVILDGWLHGVSSGLLGTNDNEGSNEQLLPDGSHTSGLLQFAHSWQVDSECVSRKADVCQNATADSLSCTFLFSSTNSPLSPCFRVVDPVQFAMECEILECVRDERADVPKPAYCSLASAYIHVCHRNYVPLELPVQCV", "length": 2991, "header": "tr|A0AC58HAT8-1|A0AC58HAT8_DANRE Computationally mapped isoform of Uncharacterized protein si:dkeyp-106c3.1 isoform X3 OS=Danio rerio OX=7955 GN=si:dkeyp-106c3.1 PE=4 SV=1 CANONICAL=A0A8M9PD97-1" }, "locus": {} }, { "isoform_ac": "A0AC58HAU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97/entry#A0AC58HAU0-1", "sequence": { "sequence": "MAMSRVCLLLQDLGLIIMLIFFSVDCQKLQQGQLCKPACPDVQKGQRHTYRYSTTISSTWKGSSSGGSQLALDCVIDINVRPGCPDMMLKLRNIQIKQSSSKRDNSVQRLKNMRESLEKNPLRFSLEGGKVTMFCPQEAEQVWTLNIKRSILSMIQTSHSGRARETVRETDVYGTCTSSYERRGPSLVKIRNLQLCLSDRIDQFWRSSVPLKEDMTVSAGLTCVQLYDDTVLKKVNCTETVSLVPLPGLLEVTETKTVSSLTLLRTLDVIPMDLAQNTGYLSSIVFEAEGQSSGRHAGPSVQEVSNIVRRLCAHLMDQQQQSELLLNLVLQLRALSSRQLRDLWHEASFKCRDDWQPLVDALSACGTENCILVNADLILNKEVDQEHILPLISFASHPTPSIISHLSALLQIPLIRPKVLLVVSSLVHRFCQQSPCSEISEVQQFVHLLKLSLEAGCQVDDHLKITELLHVLKAVENAGAAVSDLIPTLSRCVQNHSVPLELQLAAIRAFRRIPCHQDRKVLAQVFQRQQENVEVRIAAYQQLMHCPNQEIFTLVKTTLSNEKSSQVGSFVWSHLFNIQKTEDPLKKYLMESLPDDIISRDFEAEPWKYSSHMDYTVDTGVAAANVEGALVFSPQSFLPSYAMANLTVFILGRAFNLLEISLRMENLEPLLKTVFEQQPLASADHSGPSAQADSVKKKERNSNSDGCQSATFSSMRTKFTEQRKKDRTLHCWINVKMFGNDMTFMTCDDLHSYQRKLSLSTAGVVVKLLKGQEIKLSQKPVVLAEELVLPSLSGLPMRLSINMSALFSLRLKGISNYKNWSHFSLAGYIKPSALVGISVRAGVDGAIGRVGLEWVTQLKTSTSLDGAVYLHHGQNLKLVLNTPEDVMDILTFNSRVFRVSGDLKDELVVTRNLKEKNTCTPKTWSKMVGWQLCSDLTYPLTLMGKSFPPLGPVIFTLRLQKLDKGLNQYLLEAAYTFVSQRHFWMPLEATLLLFIGTPQSTIHRDVSLDVNLTPKRLILKITHPLKAILIQAQLEEINNQRSGRIELLIDNIHHYFIKGLLETVNLASEMRTHFHLDAKVVADGHPFSLSVNTTHARSRKFVIQALLKNVFNKDASFSVQLERSLEDGRRHYSIDAGFLLPSAVSLRGLGLLKQRGSEWSSAVRVRYGVKEDLEKMQECHMTQNLHSESDSIQTYRVTAAHELHCSQFINLNHKILFKHERSPVHVQSSLDISYGKQWNQSSNKHRILFNQSLRNQSGPDLTSYAVELSLRLLDRGQNYRTQLLHNNFKTQKSESSTHLKINYNNQMPLIAGVHWKDVSTKTSLQKWEGSFNMDTPWLYVYAAQKLAQPQRGITQFSSEVTTRKLVNIRGVTLEGFYKDRGKERQGQLHLFTPTFSYVKVGGWSVLGKRGVKASYSISTAWTPALHGQISVGNGKQVKTLEMSAGYGKQDLNISAVLSTLDKKLKKRLLMMTMTLADLKNPYAELQIEGAIEETRKDKRVYQKRWKLNFRQPFKFLPQSLILQETFTSDLHHKVYTLESKVLVHGNRKAIHVLTLGFQPQQPYMCSSLVQSFSTERIPQDSKICFTVQNNQNVHEIHVRLWAGNEERLEAFGQVQFHDPATFQQGITIKANLSQLIKMDFPLNVSLNIEALKSHRSKSDFEYHSEGQICIDNRIYQANTAMIVSHFGNISSSISLQADEKNSTIHLILENKAGKGSNALSIYADFHQTLLAGVTPEGHIHLYANCSSERVFLQCRVKKEDETFSAHLTGSLPHDKLHLSLSGDVVNSIQDLSALPNSVSMVGVLTQSNGLTEGELTVVVDDAVYGLEVTQQSGEDLRALLCVVIMEESLCVNISSIVTQHGCRSYTQLSHSFPWLHFAGLPFHSSAGVFMNWNNSSVCAQLELHADARGLSATLEQSSQSQVNYTEGINTGPLLAICSEQDQKDTLKVGVRANLQSSTFSFDLQGHHNISSTGLMLNISHNTPALHPYLPSDFYSKSQLRRSQSSAKCTAELLVGVSSLAFDAEILSANSGFKQALVFNHSIPQLHLLPRNLTVRTLYGGKRGSHIFTHRAQWDNQDSTHTTSSYDYTQFQQSYPELTGTALGWGLDLKVENDSQRKLGDLNMDWSLFGSREELKVQGSWALVSRQMDSSEQKQAFVSTLTQFHIHALSHGLTNRNEGISQAHISTSHRKPVNVSVTVSEHWHGDSSRGQACVFILPGQMQTLLPLVEMEGCVAVAQDGKSYSQNTELKWKDKRITQSMKYQCGVKGMHTLLVELGAQNVSPSPCPSHSLLTQIHTNLRDHLEHHVQIGLCPPQPALIWSGSHRVNSGKEMLLTHSRVSVSGHPQHSTFTLSLRNTSSSQRSNYSLLTEWQVGNWSVELASSSMVSGRSVAVQVHAKLDRSELLWLQGALGKRCLRAAAGYHTETSDDLRLLLCSEGHHWFTLEAQRGGAGIENETLALISVGAANQSLLFGAKGCGDCLWAAEARLQQLGSRIRNKLFDRFQRLQHLLLTFRRQAGDSVFLLELSAWPLSLTQRAETLLERSAVLWKAWTTGPLRHTLTHSLPNALQLLHLMSQQVQQELRKPLATLAGAYHDVTGERLDAVWQQGVQMWTRELTELLPSMLHDPHLRTPSLTALHAAVFAMDMVSQQTFQWMEARLAAMLVGVRRQLALIYKFSKSEGELMLRVPLPEGPWLMVKDAGMTEVLLEEFVLKPLLALNSMSPTAELYRLKRRIMDSPANYQAFLVADVYLVSFDGHLFQLPAACDFILAADVTKNTFSIALKSGRFKRRSLVMQMQNTTTAIHANGEVEVNCHVTHVPYTNPEVAVRKDVNFIEVSNGRGLWVSCDHHLEVCSVILDGWLHGVSSGLLGTNDNEGSNEQLLPDGSHTSGLLQFAHSWQVDSECVSRKADVCQNATADSLSCTFLFSSTNSPLSPCFRVVDPVQFAMECEILECVRDERADVPKPAYCSLASAYIHVCHRNYVPLELPVQCV", "length": 2991, "header": "tr|A0AC58HAU0-1|A0AC58HAU0_DANRE Computationally mapped isoform of Uncharacterized protein si:dkeyp-106c3.1 isoform X2 OS=Danio rerio OX=7955 GN=si:dkeyp-106c3.1 PE=4 SV=1 CANONICAL=A0A8M9PD97-1" }, "locus": {} }, { "isoform_ac": "A0AC58HAU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97/entry#A0AC58HAU4-1", "sequence": { "sequence": "MAMSRVCLLLQDLGLIIMLIFFSVDCQKLQQGQLCKPACPDVQKGQRHTYRYSTTISSTWKGSSSGGSQLALDCVIDINVRPGCPDMMLKLRNIQIKQSSSKRDNSVQRLKNMRESLEKNPLRFSLEGGKVTMFCPQEAEQVWTLNIKRSILSMIQTSHSGRARETVRETDVYGTCTSSYERRGPSLVKIRNLQLCLSDRIDQFWRSSVPLKEDMTVSAGLTCVQLYDDTVLKKVNCTETVSLVPLPGLLEVTETKTVSSLTLLRTLDVIPMDLAQNTGYLSSIVFEAEGQSSGRHAGPSVQEVSNIVRRLCAHLMDQQQQSELLLNLVLQLRALSSRQLRDLWHEASFKCRDDWQPLVDALSACGTENCILVNADLILNKEVDQEHILPLISFASHPTPSIISHLSALLQIPLIRPKVLLVVSSLVHRFCQQSPCSEISEVQQFVHLLKLSLEAGCQVDDHLKITELLHVLKAVENAGAAVSDLIPTLSRCVQNHSVPLELQLAAIRAFRRIPCHQDRKVLAQVFQRQQENVEVRIAAYQQLMHCPNQEIFTLVKTTLSNEKSSQVGSFVWSHLFNIQKTEDPLKKYLMESLPDDIISRDFEAEPWKYSSHMDYTVDTGVAAANVEGALVFSPQSFLPSYAMANLTVFILGRAFNLLEISLRMENLEPLLKTVFEQQPLASADHSGPSAQADSVKKKERNSNSDGCQSATFSSMRTKFTEQRKKDRTLHCWINVKMFGNDMTFMTCDDLHSYQRKLSLSTAGVVVKLLKGQEIKLSQKPVVLAEELVLPSLSGLPMRLSINMSALFSLRLKGISNYKNWSHFSLAGYIKPSALVGISVRAGVDGAIGRVGLEWVTQLKTSTSLDGAVYLHHGQNLKLVLNTPEDVMDILTFNSRVFRVSGDLKDELVVTRNLKEKNTCTPKTWSKMVGWQLCSDLTYPLTLMGKSFPPLGPVIFTLRLQKLDKGLNQYLLEAAYTFVSQRHFWMPLEATLLLFIGTPQSTIHRDVSLDVNLTPKRLILKITHPLKAILIQAQLEEINNQRSGRIELLIDNIHHYFIKGLLETVNLASEMRTHFHLDAKVVADGHPFSLSVNTTHARSRKFVIQALLKNVFNKDASFSVQLERSLEDGRRHYSIDAGFLLPSAVSLRGLGLLKQRGSEWSSAVRVRYGVKDLEKMQECHMTQNLHSESDSIQTYRVTAAHELHCSQFINLNHKILFKHERSPVHVQSSLDISYGKQWNQSSNKHRILFNQSLRNQSGPDLTSYAVELSLRLLDRGQNYRTQLLHNNFKTQKSESSTHLKINYNNQMPLIAGVHWKDVSTKTSLQKWEGSFNMDTPWLYVYAAQKLAQPQRGITQFSSEVTTRKLVNIRGVTLEGFYKDRGKERQGQLHLFTPTFSYVKVGGWSVLGKRGVKASYSISTAWTPALHGQISVGNGKQVKTLEMSAGYGKQDLNISAVLSTLDKKLKKRLLMMTMTLADLKNPYAELQIEGAIEETRKDKRVYQKRWKLNFRQPFKFLPQSLILQETFTSDLHHKVYTLESKVLVHGNRKAIHVLTLGFQPQQPYMCSSLVQSFSTERIPQDSKICFTVQNNQNVHEIHVRLWAGNEERLEAFGQVQFHDPATFQQGITIKANLSQLIKMDFPLNVSLNIEALKSHRSKSDFEYHSEGQICIDNRIYQANTAMIVSHFGNISSSISLQADEKNSTIHLILENKAGKGSNALSIYADFHQTLLAGVTPEGHIHLYANCSSERVFLQCRVKKEDETFSAHLTGSLPHDKLHLSLSGDVVNSIQDLSALPNSVSMVGVLTQSNGLTEGELTVVVDDAVYGLEVTQQSGEDLRALLCVVIMEESLCVNISSIVTQHGCRSYTQLSHSFPWLHFAGLPFHSSAGVFMNWNNSSVCAQLELHADARGLSATLEQSSQSQVNYTEGINTGPLLAICSEQDQKDTLKVGVRANLQSSTFSFDLQGHHNISSTGLMLNISHNTPALHPYLPSDFYSKSQLRRSQSSAKCTAELLVGVSSLAFDAEILSANSGFKQALVFNHSIPQLHLLPRNLTVRTLYGGKRGSHIFTHRAQWDNQDSTHTTSSYDYTQFQQSYPELTGTALGWGLDLKVENDSQRKLGDLNMDWSLFGSREELKVQGSWALVSRQMDSSEQKQAFVSTLTQFHIHALSHGLTNRNEGISQAHISTSHRKPVNVSVTVSEHWHGDSSRGQACVFILPGQMQTLLPLVEMEGCVAVAQDGKSYSQNTELKWKDKRITQSMKYQCGVKGMHTLLVELGAQNVSPSPCPSHSLLTQIHTNLRDHLEHHVQIGLCPPQPALIWSGSHRVNSGKEMLLTHSRVSVSGHPQHSTFTLSLRNTSSSQRSNYSLLTEWQVGNWSVELASSSMVSGRSVAVQVHAKLDRSELLWLQGALGKRCLRAAAGYHTETSDDLRLLLCSEGHHWFTLEAQRGGAGIENETLALISVGAANQSLLFGAKGCGDCLWAAEARLQQLGSRIRNKLFDRFQRLQHLLLTFRRQAGDSVFLLELSAWPLSLTQRAETLLERSAVLWKAWTTGPLRHTLTHSLPNALQLLHLMSQQVQQELRKPLATLAGAYHDVTGERLDAVWQQGVQMWTRELTELLPSMLHDPHLRTPSLTALHAAVFAMDMVSQQTFQWMEARLAAMLVGVRRQLALIYKFSKSEGELMLRVPLPEGPWLMVKDAGMTEVLLEEFVLKPLLALNSMSPTAELYRLKRRIMDSPANYQAFLVADVYLVSFDGHLFQLPAACDFILAADVTKNTFSIALKSGRFKRRSLVMQMQNTTTAIHANGEVEVNCHVTHVPYTNPEVAVRKDVNFIEVSNGRGLWVSCDHHLEVCSVILDGWLHGVSSGLLGTNDNEGSNEQLLPDGSHTSGLLQFAHSWQVDSECVSRKADVCQNATADSLSCTFLFSSTNSPLSPCFRVVDPVQFAMECEILECVRDERADVPKPAYCSLASAYIHVCHRNYVPLELPVQCV", "length": 2990, "header": "tr|A0AC58HAU4-1|A0AC58HAU4_DANRE Computationally mapped isoform of Uncharacterized protein si:dkeyp-106c3.1 isoform X4 OS=Danio rerio OX=7955 GN=si:dkeyp-106c3.1 PE=4 SV=1 CANONICAL=A0A8M9PD97-1" }, "locus": {} }, { "isoform_ac": "A0AC58HAV3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97/entry#A0AC58HAV3-1", "sequence": { "sequence": "MHLWELYGSFNMDTPWLYVYAAQKLAQPQRGITQFSSEVTTRKLVNIRGVTLEGFYKDRGKERQGQLHLFTPTFSYVKVGGWSVLGKRGVKASYSISTAWTPALHGQISVGNGKQVKTLEMSAGYGKQDLNISAVLSTLDKKLKKRLLMMTMTLADLKNPYAELQIEGAIEETRKDKRVYQKRWKLNFRQPFKFLPQSLILQETFTSDLHHKVYTLESKVLVHGNRKAIHVLTLGFQPQQPYMCSSLVQSFSTERIPQDSKICFTVQNNQNVHEIHVRLWAGNEERLEAFGQVQFHDPATFQQGITIKANLSQLIKMDFPLNVSLNIEALKSHRSKSDFEYHSEGQICIDNRIYQANTAMIVSHFGNISSSISLQADEKNSTIHLILENKAGKGSNALSIYADFHQTLLAGVTPEGHIHLYANCSSERVFLQCRVKKEDETFSAHLTGSLPHDKLHLSLSGDVVNSIQDLSALPNSVSMVGVLTQSNGLTEGELTVVVDDAVYGLEVTQQSGEDLRALLCVVIMEESLCVNISSIVTQHGCRSYTQLSHSFPWLHFAAGLPFHSSAGVFMNWNNSSVCAQLELHADARGLSATLEQSSQSQVNYTEGINTGPLLAICSEQDQKDTLKVGVRANLQSSTFSFDLQGHHNISSTGLMLNISHNTPALHPYLPSDFYSKSQLRRSQSSAKCTAELLVGVSSLAFDAEILSANSGFKQALVFNHSIPQLHLLPRNLTVRTLYGGKRGSHIFTHRAQWDNQDSTHTTSSYDYTQFQQSYPELTGTALGWGLDLKVENDSQRKLGDLNMDWSLFGSREELKVQGSWALVSRQMDSSEQKQAFVSTLTQFHIHALSHGLTNRNEGISQAHISTSHRKPVNVSVTVSEHWHGDSSRGQACVFILPGQMQTLLPLVEMEGCVAVAQDGKSYSQNTELKWKDKRITQSMKYQCGVKGMHTLLVELGAQNVSPSPCPSHSLLTQIHTNLRDHLEHHVQIGLCPPQPALIWSGSHRVNSGKEMLLTHSRVSVSGHPQHSTFTLSLRNTSSSQRSNYSLLTEWQVGNWSVELASSSMVSGRSVAVQVHAKLDRSELLWLQGALGKRCLRAAAGYHTETSDDLRLLLCSEGHHWFTLEAQRGGAGIENETLALISVGAANQSLLFGAKGCGDCLWAAEARLQQLGSRIRNKLFDRFQRLQHLLLTFRRQAGDSVFLLELSAWPLSLTQRAETLLERSAVLWKAWTTGPLRHTLTHSLPNALQLLHLMSQQVQQELRKPLATLAGAYHDVTGERLDAVWQQGVQMWTRELTELLPSMLHDPHLRTPSLTALHAAVFAMDMVSQQTFQWMEARLAAMLVGVRRQLALIYKFSKSEGELMLRVPLPEGPWLMVKDAGMTEVLLEEFVLKPLLALNSMSPTAELYRLKRRIMDSPANYQAFLVADVYLVSFDGHLFQLPAACDFILAADVTKNTFSIALKSGRFKRRSLVMQMQNTTTAIHANGEVEVNCHVTHVPYTNPEVAVRKDVNFIEVSNGRGLWVSCDHHLEVCSVILDGWLHGVSSGLLGTNDNEGSNEQLLPDGSHTSGLLQFAHSWQVDSECVSRKADVCQNATADSLSCTFLFSSTNSPLSPCFRVVDPVQFAMECEILECVRDERADVPKPAYCSLASAYIHVCHRNYVPLELPVQCV", "length": 1671, "header": "tr|A0AC58HAV3-1|A0AC58HAV3_DANRE Computationally mapped isoform of Uncharacterized protein si:dkeyp-106c3.1 isoform X6 OS=Danio rerio OX=7955 GN=si:dkeyp-106c3.1 PE=4 SV=1 CANONICAL=A0A8M9PD97-1" }, "locus": {} }, { "isoform_ac": "A0AC58HAV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97/entry#A0AC58HAV5-1", "sequence": { "sequence": "MHLWELYGSFNMDTPWLYVYAAQKLAQPQRGITQFSSEVTTRKLVNIRGVTLEGFYKDRGKERQGQLHLFTPTFSYVKVGGWSVLGKRGVKASYSISTAWTPALHGQISVGNGKQVKTLEMSAGYGKQDLNISAVLSTLDKKLKKRLLMMTMTLADLKNPYAELQIEGAIEETRKDKRVYQKRWKLNFRQPFKFLPQSLILQETFTSDLHHKVYTLESKVLVHGNRKAIHVLTLGFQPQQPYMCSSLVQSFSTERIPQDSKICFTVQNNQNVHEIHVRLWAGNEERLEAFGQVQFHDPATFQQGITIKANLSQLIKMDFPLNVSLNIEALKSHRSKSDFEYHSEGQICIDNRIYQANTAMIVSHFGNISSSISLQADEKNSTIHLILENKAGKGSNALSIYADFHQTLLAGVTPEGHIHLYANCSSERVFLQCRVKKEDETFSAHLTGSLPHDKLHLSLSGDVVNSIQDLSALPNSVSMVGVLTQSNGLTEGELTVVVDDAVYGLEVTQQSGEDLRALLCVVIMEESLCVNISSIVTQHGCRSYTQLSHSFPWLHFAGLPFHSSAGVFMNWNNSSVCAQLELHADARGLSATLEQSSQSQVNYTEGINTGPLLAICSEQDQKDTLKVGVRANLQSSTFSFDLQGHHNISSTGLMLNISHNTPALHPYLPSDFYSKSQLRRSQSSAKCTAELLVGVSSLAFDAEILSANSGFKQALVFNHSIPQLHLLPRNLTVRTLYGGKRGSHIFTHRAQWDNQDSTHTTSSYDYTQFQQSYPELTGTALGWGLDLKVENDSQRKLGDLNMDWSLFGSREELKVQGSWALVSRQMDSSEQKQAFVSTLTQFHIHALSHGLTNRNEGISQAHISTSHRKPVNVSVTVSEHWHGDSSRGQACVFILPGQMQTLLPLVEMEGCVAVAQDGKSYSQNTELKWKDKRITQSMKYQCGVKGMHTLLVELGAQNVSPSPCPSHSLLTQIHTNLRDHLEHHVQIGLCPPQPALIWSGSHRVNSGKEMLLTHSRVSVSGHPQHSTFTLSLRNTSSSQRSNYSLLTEWQVGNWSVELASSSMVSGRSVAVQVHAKLDRSELLWLQGALGKRCLRAAAGYHTETSDDLRLLLCSEGHHWFTLEAQRGGAGIENETLALISVGAANQSLLFGAKGCGDCLWAAEARLQQLGSRIRNKLFDRFQRLQHLLLTFRRQAGDSVFLLELSAWPLSLTQRAETLLERSAVLWKAWTTGPLRHTLTHSLPNALQLLHLMSQQVQQELRKPLATLAGAYHDVTGERLDAVWQQGVQMWTRELTELLPSMLHDPHLRTPSLTALHAAVFAMDMVSQQTFQWMEARLAAMLVGVRRQLALIYKFSKSEGELMLRVPLPEGPWLMVKDAGMTEVLLEEFVLKPLLALNSMSPTAELYRLKRRIMDSPANYQAFLVADVYLVSFDGHLFQLPAACDFILAADVTKNTFSIALKSGRFKRRSLVMQMQNTTTAIHANGEVEVNCHVTHVPYTNPEVAVRKDVNFIEVSNGRGLWVSCDHHLEVCSVILDGWLHGVSSGLLGTNDNEGSNEQLLPDGSHTSGLLQFAHSWQVDSECVSRKADVCQNATADSLSCTFLFSSTNSPLSPCFRVVDPVQFAMECEILECVRDERADVPKPAYCSLASAYIHVCHRNYVPLELPVQCV", "length": 1670, "header": "tr|A0AC58HAV5-1|A0AC58HAV5_DANRE Computationally mapped isoform of Uncharacterized protein si:dkeyp-106c3.1 isoform X7 OS=Danio rerio OX=7955 GN=si:dkeyp-106c3.1 PE=4 SV=1 CANONICAL=A0A8M9PD97-1" }, "locus": {} }, { "isoform_ac": "A0AC58HAV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97/entry#A0AC58HAV7-1", "sequence": { "sequence": "MMLKLRNIQIKQSSSKRDNSVQRLKNMRESLEKNPLRFSLEGGKVTMFCPQEAEQVWTLNIKRSILSMIQTSHSGRARETVRETDVYGTCTSSYERRGPSLVKIRNLQLCLSDRIDQFWRSSVPLKEDMTVSAGLTCVQLYDDTVLKKVNCTETVSLVPLPGLLEVTETKTVSSLTLLRTLDVIPMDLAQNTGYLSSIVFEAEGQSSGRHAGPSVQEVSNIVRRLCAHLMDQQQQSELLLNLVLQLRALSSRQLRDLWHEASFKCRDDWQPLVDALSACGTENCILVNADLILNKEVDQEHILPLISFASHPTPSIISHLSALLQIPLIRPKVLLVVSSLVHRFCQQSPCSEISEVQQFVHLLKLSLEAGCQVDDHLKITELLHVLKAVENAGAAVSDLIPTLSRCVQNHSVPLELQLAAIRAFRRIPCHQDRKVLAQVFQRQQENVEVRIAAYQQLMHCPNQEIFTLVKTTLSNEKSSQVGSFVWSHLFNIQKTEDPLKKYLMESLPDDIISRDFEAEPWKYSSHMDYTVDTGVAAANVEGALVFSPQSFLPSYAMANLTVFILGRAFNLLEISLRMENLEPLLKTVFEQQPLASADHSGPSAQADSVKKKERNSNSDGCQSATFSSMRTKFTEQRKKDRTLHCWINVKMFGNDMTFMTCDDLHSYQRKLSLSTAGVVVKLLKGQEIKLSQKPVVLAEELVLPSLSGLPMRLSINMSALFSLRLKGISNYKNWSHFSLAGYIKPSALVGISVRAGVDGAIGRVGLEWVTQLKTSTSLDGAVYLHHGQNLKLVLNTPEDVMDILTFNSRVFRVSGDLKDELVVTRNLKEKNTCTPKTWSKMVGWQLCSDLTYPLTLMGKSFPPLGPVIFTLRLQKLDKGLNQYLLEAAYTFVSQRHFWMPLEATLLLFIGTPQSTIHRDVSLDVNLTPKRLILKITHPLKAILIQAQLEEINNQRSGRIELLIDNIHHYFIKGLLETVNLASEMRTHFHLDAKVVADGHPFSLSVNTTHARSRKFVIQALLKNVFNKDASFSVQLERSLEDGRRHYSIDAGFLLPSAVSLRGLGLLKQRGSEWSSAVRVRYGVKEDLEKMQECHMTQNLHSESDSIQTYRVTAAHELHCSQFINLNHKILFKHERSPVHVQSSLDISYGKQWNQSSNKHRILFNQSLRNQSGPDLTSYAVELSLRLLDRGQNYRTQLLHNNFKTQKSESSTHLKINYNNQMPLIAGVHWKDVSTKTSLQKWEGSFNMDTPWLYVYAAQKLAQPQRGITQFSSEVTTRKLVNIRGVTLEGFYKDRGKERQGQLHLFTPTFSYVKVGGWSVLGKRGVKASYSISTAWTPALHGQISVGNGKQVKTLEMSAGYGKQDLNISAVLSTLDKKLKKRLLMMTMTLADLKNPYAELQIEGAIEETRKDKRVYQKRWKLNFRQPFKFLPQSLILQETFTSDLHHKVYTLESKVLVHGNRKAIHVLTLGFQPQQPYMCSSLVQSFSTERIPQDSKICFTVQNNQNVHEIHVRLWAGNEERLEAFGQVQFHDPATFQQGITIKANLSQLIKMDFPLNVSLNIEALKSHRSKSDFEYHSEGQICIDNRIYQANTAMIVSHFGNISSSISLQADEKNSTIHLILENKAGKGSNALSIYADFHQTLLAGVTPEGHIHLYANCSSERVFLQCRVKKEDETFSAHLTGSLPHDKLHLSLSGDVVNSIQDLSALPNSVSMVGVLTQSNGLTEGELTVVVDDAVYGLEVTQQSGEDLRALLCVVIMEESLCVNISSIVTQHGCRSYTQLSHSFPWLHFAGLPFHSSAGVFMNWNNSSVCAQLELHADARGLSATLEQSSQSQVNYTEGINTGPLLAICSEQDQKDTLKVGVRANLQSSTFSFDLQGHHNISSTGLMLNISHNTPALHPYLPSDFYSKSQLRRSQSSAKCTAELLVGVSSLAFDAEILSANSGFKQALVFNHSIPQLHLLPRNLTVRTLYGGKRGSHIFTHRAQWDNQDSTHTTSSYDYTQFQQSYPELTGTALGWGLDLKVENDSQRKLGDLNMDWSLFGSREELKVQGSWALVSRQMDSSEQKQAFVSTLTQFHIHALSHGLTNRNEGISQAHISTSHRKPVNVSVTVSEHWHGDSSRGQACVFILPGQMQTLLPLVEMEGCVAVAQDGKSYSQNTELKWKDKRITQSMKYQCGVKGMHTLLVELGAQNVSPSPCPSHSLLTQIHTNLRDHLEHHVQIGLCPPQPALIWSGSHRVNSGKEMLLTHSRVSVSGHPQHSTFTLSLRNTSSSQRSNYSLLTEWQVGNWSVELASSSMVSGRSVAVQVHAKLDRSELLWLQGALGKRCLRAAAGYHTETSDDLRLLLCSEGHHWFTLEAQRGGAGIENETLALISVGAANQSLLFGAKGCGDCLWAAEARLQQLGSRIRNKLFDRFQRLQHLLLTFRRQAGDSVFLLELSAWPLSLTQRAETLLERSAVLWKAWTTGPLRHTLTHSLPNALQLLHLMSQQVQQELRKPLATLAGAYHDVTGERLDAVWQQGVQMWTRELTELLPSMLHDPHLRTPSLTALHAAVFAMDMVSQQTFQWMEARLAAMLVGVRRQLALIYKFSKSEGELMLRVPLPEGPWLMVKDAGMTEVLLEEFVLKPLLALNSMSPTAELYRLKRRIMDSPANYQAFLVADVYLVSFDGHLFQLPAACDFILAADVTKNTFSIALKSGRFKRRSLVMQMQNTTTAIHANGEVEVNCHVTHVPYTNPEVAVRKDVNFIEVSNGRGLWVSCDHHLEVCSVILDGWLHGVSSGLLGTNDNEGSNEQLLPDGSHTSGLLQFAHSWQVDSECVSRKADVCQNATADSLSCTFLFSSTNSPLSPCFRVVDPVQFAMECEILECVRDERADVPKPAYCSLASAYIHVCHRNYVPLELPVQCV", "length": 2905, "header": "tr|A0AC58HAV7-1|A0AC58HAV7_DANRE Computationally mapped isoform of Uncharacterized protein si:dkeyp-106c3.1 isoform X5 OS=Danio rerio OX=7955 GN=si:dkeyp-106c3.1 PE=4 SV=1 CANONICAL=A0A8M9PD97-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1198, "start_aa": "Thr", "end_pos": 1198, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1198", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:558820", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558820", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q414-1", "protein_name": "Apolipoprotein B-100", "gene_name": "Apob", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPRKPALRTPLLLLFLLLFLDTSVWAQDEVLENLSFSCPKDATRFKHLRKYVYNYEAESSSGVQGTADSRSATKINCKVELEVPQICGFIMRTNQCTLKEVYGFNPEGKALMKKTKNSEEFAAAMSRYELKLAIPEGKQIVLYPDKDEPKYILNIKRGIISALLVPPETEEDQQELFLDTVYGNCSTQVTVNSRKGTVPTEMSTERNLQQCDGFQPISTSVSPLALIKGLVHPLSTLISSSQTCQYTLDPKRKHVSEAVCDEQHLFLPFSYKNKYGIMTRVTQKLSLEDTPKINSRFFSEGTNRMGLAFESTKSTSSPKQADAVLKTLQELKKLSISEQNAQRANLFNKLVTELRGLTGEAITSLLPQLIEVSSPITLQALVQCGQPQCYTHILQWLKTEKAHPLLVDIVTYLMALIPNPSTQRLQEIFNTAKEQQSRATLYALSHAVNSYFDVDHSRSPVLQDIAGYLLKQIDNECTGNEDHTFLILRVIGNMGRTMEQVMPALKSSVLSCVRSTKPSLLIQKAALQALRKMELEDEVRTILFDTFVNGVAPVEKRLAAYLLLMKNPSSSDINKIAQLLQWEQSEQVKNFVASHIANILNSEELYVQDLKVLIKNALENSQFPTIMDFRKFSRNYQISKSASLPMFDPVSVKIEGNLIFDPSSYLPRESLLKTTLTVFGLASLDLFEIGLEGKGFEPTLEALFGKQGFFPDSVNKALYWVNGRVPDGVSKVLVDHFGYTTDGKHEQDMVNGIMPIVDKLIKDLKSKEIPEARAYLRILGKELSFVRLQDLQVLGKLLLSGAQTLQGIPQMVVQAIREGSKNDLFLHYIFMDNAFELPTGAGLQLQVSSSGVFTPGIKAGVRLELANIQAELVAKPSVSLEFVTNMGIIIPDFAKSSVQMNTNFFHESGLEARVALKAGQLKVIIPSPKRPVKLFSGSNTLHLVSTTKTEVIPPLVENRQSWSTCKPLFTGMNYCTTGAYSNASSTESASYYPLTGDTRYELELRPTGEVEQYSATATYELLKEDKSLVDTLKFLVQAEGVQQSEATVLFKYNRRSRTLSSEVLIPGFDVNFGTILRVNDESAKDKNTYKLILDIQNKKITEVSLVGHLSYDKKGDGKIKGVVSIPRLQAEARSEVHTHWSSTKLLFQMDSSATAYGSTISKRVTWRYDNEIIEFDWNTGTNVDTKKVASNFPVDLSHYPRMLHEYANGLLDHRVPQTDVTFRDMGSKLIVATNTWLQMATRGLPYPQTLQDHLNSLSELNLLKMGLSDFHIPDNLFLKTDGRVKYTMNRNKINIDIPLPLGGKSSKDLKMPESVRTPALNFKSVGFHLPSREVQVPTFTIPKTHQLQVPLLGVLDLSTNVYSNLYNWSASYTGGNTSRDHFSLQAQYRMKTDSVVDLFSYSVQGSGETTYDSKNTFTLSCDGSLHHKFLDSKFKVSHVEKFGNSPVSKGLLTFETSSALGPQMSATVHLDSKKKQHLYVKDIKVDGQFRASSFYAQGKYGLSCERDVTTGQLSGESNMRFNSTYFQGTNQIVGMYQDGALSITSTSDLQDGIFKNTASLKYENYELTLKSDSSGQYENFAASNKLDVTFSTQSALLRSEHQANYKSLRLVTLLSGSLTSQGVELNADILGTDKINTGAHKATLKIARDGLSTSATTNLKYSPLLLENELNAELGLSGASMKLSTNGRFKEHHAKFSLDGRAALTEVSLGSIYQAMILGADSKNIFNFKLSREGLRLSNDLMGSYAEMKLDHTHSLNIAGLSLDFFSKMDNIYSGDKFYKQNFNLQLQPYSFITTLSNDLRYGALDLTNNGRFRLEPLKLNVGGNFKGTYQNNELKHIYTISYTDLVVASYRADTVAKVQGVEFSHRLNADIEGLTSSVDVTTSYNSDPLHFNNVFHFSLAPFTLGIDTHTSGDGKLSFWGEHTGQLYSKFLLKAEPLALIVSHDYKGSTSHSLPYESSISTALEHTVSALLTPAEQTSTWKFKTKLNDKVYSQDFEAYNTKDKIGVELSGRADLSGLYSPIKLPFFYSEPVNVLNGLEVNDAVDKPQEFTIIAVVKYDKNQDVHTINLPFFKSLPDYLERNRRGMISLLEAMRGELQRLSVDQFVRKYRAALSRLPQQIHHYLNASDWERQVAGAKEKITSFMENYRITDNDVLIAIDSAKINFNEKLSQLETYAIQFDQYIKDNYDPHDLKRTIAEIIDRIIEKLKILDEQYHIRVNLAKSIHNLYLFVENVDLNQVSSSNTSWIQNVDSNYQVRIQIQEKLQQLRTQIQNIDIQQLAAEVKRQMDAIDVTMHLDQLRTAILFQRISDIIDRVKYFVMNLIEDFKVTEKINTFRVIVRELIEKYEVDQHIQVLMDKSVELAHRYSLSEPLQKLSNVLQRIEIKDYYEKLVGFIDDTVEWLKALSFKNTIEELNRLTDMLVKKLKAFDYHQFVDKTNSKIREMTQRINAEIQALKLPQKMEALKLLVEDFKTTVSNSLERLKDTKVTVVIDWLQDILTQMKDHFQDTLEDVRDRIYQMDIQRELEHFLSLVNQVYSTLVTYMSDWWTLTAKNITDFAEQYSIQNWAESIKVLVEQGFIVPEMQTFLWTMPAFEVSLRALQEGNFQTPVFIVPLTDLRIPSIRINFKMLKNIKIPLRFSTPEFTLLNTFHVHSFTIDLLEIKAKIIRTIDQILSSELQWPLPEMYLRDLDVVNIPLARLTLPDFHVPEITIPEFTIPNVNLKDLHVPDLHIPEFQLPHLSHTIEIPAFGKLHSILKIQSPLFILDANANIQNVTTSGNKAEIVASVTAKGESQFEALNFDFQAQAQFLELNPHPPVLKESMNFSSKHVRMEHEGEIVFDGKAIEGKSDTVASLHTEKNEVEFNNGMTVKVNNQLTLDSHTKYFHKLSVPRLDFSSKASLNNEIKTLLEAGHVALTSSGTGSWNWACPNFSDEGIHSSQISFTVDGPIAFVGLSNNINGKHLRVIQKLTYESGFLNYSKFEVESKVESQHVGSSILTANGRALLKDAKAEMTGEHNANLNGKVIGTLKNSLFFSAQPFEITASTNNEGNLKVGFPLKLTGKIDFLNNYALFLSPRAQQASWQASTRFNQYKYNQNFSAINNEHNIEASIGMNGDANLDFLNIPLTIPEINLPYTEFKTPLLKDFSIWEETGLKEFLKTTKQSFDLSVKAQYKKNSDKHSIVVPLGMFYEFILNNVNSWDRKFEKVRNNALHFLTTSYNEAKIKVDKYKTENSLNQPSGTFQNHGYTIPVVNIEVSPFAVETLASSHVIPTAISTPSVTIPGPNIMVPSYKLVLPPLELPVFHGPGNLFKFFLPDFKGFNTIDNIYIPAMGNFTYDFSFKSSVITLNTNAGLYNQSDIVAHFLSSSSFVTDALQYKLEGTSRLMRKRGLKLATAVSLTNKFVKGSHDSTISLTKKNMEASVRTTANLHAPIFSMNFKQELNGNTKSKPTVSSSIELNYDFNSSKLHSTATGGIDHKFSLESLTSYFSIESFTKGNIKSSFLSQEYSGSVANEANVYLNSKGTRSSVRLQGASKVDGIWNVEVGENFAGEATLQRIYTTWEHNMKNHLQVYSYFFTKGKQTCRATLELSPWTMSTLLQVHVSQLSSLLDLHHFDQEVILKANTKNQKISWKGGVQVESRVLQHNAQFSNDQEEIRLDLAGSLDGQLWDLEAIFLPVYGKSLQELLQMDGKRQYLQASTSLLYTKNPNGYLLSLPVQELADRFIIPGIKLNDFSGVKIYKKLSTSPFALNLTMLPKVKFPGIDLLTQYSTPEGSSVPIFEATIPEIHLTVSQFTLPKSLPVGNTVFDLNKLANMIADVDLPSVTLPEQTIVIPPLEFSVPAGIFIPFFGELTARAGMASPLYNVTWSAGWKTKADHVETFLDSMCTSTLQFLEYALKVVETHKIEEDLLTYNIKGTLQHCDFNVEYNEDGLFKGLWDWQGEAHLDITSPALTDFHLYYKEDKTSLSASAASSTIGTVGLDSSTDDQSVELNVYFHPQSPPEKKLSIFKTEWRYKESDGERYIKINWEEEAASRLLGSLKSNVPKASKAIYDYANKYHLEYVSSELRKSLQVNAEHARRMVDEMNMSFQRVARDTYQNLYEEMLAQKSLSIPENLKKRVLDSIVHVTQKYHMAVMWLMDSFIHFLKFNRVQFPGYAGTYTVDELYTIVMKETKKSLSQLFNGLGNLLSYVQNQVEKSRLINDITFKCPFFSKPCKLKDLILIFREELNILSNIGQQDIKFTTILSSLQGFLERVLDIIEEQIKCLKDNESTCVADHINMVFKIQVPYAFKSLREDIYFVLGEFNDFLQSILQEGSYKLQQVHQYMKALREEYFDPSMVGWTVKYYEIEENMVELIKTLLVSFRDVYSEYSVTAADFASKMSTQVEQFVSRDIREYLSMLTDINGKWMEKIAELSIVAKETMKSWVTAVAKIMSDYPQQFHSNLQDFSDQLSSYYEKFVGESTRLIDLSIQNYHVFLRYITELLRKLQVATANNVSPYIKLAQGELMITF", "length": 4505 }, "evidence": [ { "id": "FB:FBgn0032136", "url": "https://alliancegenome.org/gene/FB:FBgn0032136#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7KTG2-1", "protein_name": "Apolipoprotein lipid transfer particle", "gene_name": "Apoltp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGGLKPQAAIWLLLLIAHTQAVRENPLKDPRICGRPQCDSKSAKFNYGEQLYKYQYTVAVRTEFAGSGDNSSDLLLKSDLEIFFPKPCEGYLRINDAKLYDTLDELNDNESDSSEKTKEYDYYDNLANEESESQNYDNMHPKSSDFNVDLTKNLLRFAFHDGLISEVCPQEQETPWVLNIKKGILSAFQNTMMRFDVDANTTETDVSGQCQVQYALEDTDSSYVTIRKTKDINSCRQRYATHSVLQTTPYTFRDDKTIWPILKSQSHCNLTIDNNVYKEIKCLETHLLVPFSNASSGALTTSTSRLKLDGVESYSAGEFLEQNPELVERRATLVFDHTPAVKPSHDEIKAARELLVEMCRVGFPNIQREFIDVFTNFLQTSKSLDYKTLSVLLQRSASTCEQGRNHLLESLPFIGSTASYKVMRDQIINEKLTKQMAHDWMTALSFITRPDEETLETFHSILEYAKNRLDAEYTLGATAVVHSFCKHHEACEENLRVQQIINLLETEFLNLYNLFKGERRTRERMVILLKGLGNIGVVSSAFAEQLQWIIREDEAPVDIRLHGILAFRRVDCARHRSYFLDNYGNYTLNSELRIYSYLQAMRCPDYISVGVIKSILEHEEINQVGSFVWSHLTNLAKSNSPVRIEAQGLLLNDELSERFKMDIRKFSRNYEHSLFFDEYNFGTTTDANVIFGTDSYLPRIASVNFTADLFGQSVNFFEFTARAEGLEELAANAFGPKGPLSGQLLRKKLSFLNRWLGNESAEEDDTLENLLSLDNLRLKRKAQEQARASEEEVDEDYDFEESLEGNKRQKRDVSTTRKQEIDRNVDSLGYKLKYDYNNPRAQFGLRVFGNDLRYFNVESLVEVMALAAKFNPFQQAKNVLSGKEFTYTKSRVFLDASYTVPLAVGLPLAIHAFGASSIDLRVSGNLDEMDPPTDWHFDVEGQFKPSVSVDVITTMQTDMFWEQSGIKVKSNLYSNSELVAKLKVRGRNLVSFSFDLPRDKNEIFSVRSELLVQKREEQLPQAGIANRSANSTCTWPVLDQAIGLQMCSHYSVPDLSNATEIYPSLLLAGPLNFSLILKKSDLSAKKYVFEYKWDQQEEDNNFSLVFTTPGSKVPRVLVANVTKVPDAFNASVAFVNGPNRVSAGCSYDGNPDFRRLDIYLDTNGNRSLDLGMELRRHQDFTAWIYNPRMLLAINGVNITGLAGTVKVNEKNGIKQHDVDLSFETKKLQAVIKGNVVQSEITTSTNMTIKYRFQANKIEEINFAGKLVNNGDKSKTEYRGNMKLQTSAYPKLNFASESTWLSLQGHTEGMITYNNAPDYVNPNYTSLVRLIFARSHSEDSFLDGTQTRASLELKLPRSKIDYRILVKHKEHIKNGTEHNVIVGLKYTPEKEITGLFSVHLPRRNLFAIDAYMNVTVPEFNSCTASLKVNEKATKDYIIFINGSWFTGHSVAVKANYKDRSSRVQALHHLKMIVESPSFNITSLNIIYRRKQLLIFYDIQAKYDQDPYGLTIQYASNAHNRNTNAEVRLKVKERDYWINAKLLSEQPKLLQLEIHMDKIRDVHIQVGLLNVDKRKELSLELKWDANRDPSQRLGLLAEYNSPGTKHYDGNLMITYPERTIHFGFNSFTGGPKYFGKVHASWSINEVIEFEYEAGILPGHTLHNWVKAELRTPFDGWRVNSLDAGIYSLKNLILVNSTLFWADDQKLQVGYKSDYDVNDQLMSFDVRFGINSTIRDIPTINVKVKHWMDVKKVDTELYLGYSGQNDTFNTYSMDSSWEIEKNQRYNNYSGLVHLVSPFKGYEKGGLVAHFSLSDQRVVSGAASLNFDLREFTLTMNGYVKKFTDNMLTVNITTPLEKFGTINARFGLNEKKRHAVAEVRAPTAALGVEVLADIKNLLNFDVKLSVATPIESFQQAAIFALFNPERVDMRGLWNNVTLGFTGVWHMQNITDFEYSYHVFTPLAGFEENGFIVQLLKRKEFVFQLHGKMSNYKLGVKINGEPKSDLVNQLGSNKMELEMLYDADFKPLNAETDYKPDADEEYFSYFTNFQVDTLVWPTIVGNVDIQEIIDFYLVVGHVELPQGKVEFKDRLHYPDYINVHNLLTVTTPFAVAKNIKSIVEYHVDLNFNAFYERVKFIVNDDKDNTQELGFVFNYTALQDNVKPKAHDVQVTLLTPYEMLHEIYVHGHIELDDNAYKGNISAVTAHTHLSMAASIENEDNFLETSVGIQLETDAIPHYGCQVYFKKDFSAVDKAIDIRFEVTDNGTLNQLHISTDWHTDPSYIVNANGRIKTTMLPLQMASTSVLVIQGQNPHLNFDLNLLSQNGQSIAYGARANKKKDVFNIEVWTPMKNFRNISMHGTAIRSPRDPGRYDVSGFLYRNMATYEVTGAVRMTNSLPIDVVLRVQPKAGGRDGVIELNIHEAGPKKIRFSFSAIEDGKMCQMSGGYSVSKTNGAMDFSVLVESTEPEIARINFYGNLSPNSEGSLVGDLSLETPWKALGIDTVHLHSDVGFLNKGGHIVGEYKIGQYIGRGSCLWSWILAEDMQLVLENYLERPNAKPRIVHASAKYQNPGQTFTQLQAGGRLSVDSKWNLDVNGSAEYKSVDDFKFRVITALPLPVGDRHQLSASYQGNVISQQFNNPDFVLEASYESFEAQNKLLSRISYKNATNNLKGLGHVEWGKIQNLSVVEGDFELLHKQGAQREFSAKIITPKFKNEHTFALTGSYDLEKSGHHNVVGSLDYPASRRITDLDVSVSSLSNMHGIFNSTLPTFLNVSWLKTDFNFTTNNGKSYRYCRCFWPQDTAYFKLNSNYDSDSSNFNHNLNGNVEIEVPLATRHRADIVYGLQKRRNQDAGNVKVVYNEKQVLDGKYKRLEQAKAPIYKETTDISLENEVKPLGIHFVSTRDASDPAGSQDVKHIEIYELRNTQNFNLTGELHSRATLKAQDFKVVAIHPNRAVVLSTKYEDVSPEVVRHHSKLELSETAWIGYNLELGNFSKVGNESQSFALEIFYPKRNLSSSGQYYMTDTNFNSDLSFQWLGGNYDQQPKIIHSNLQWKAEPLHRGDREHRTIALTVAHPLLEKDINCKATYYRGLRDLLRTHLTIDYSEYPDQLIELGAQLTDRYSELGHTNYTFHVYGKHIASELDVQLNGTLAAMNSYYKTESTAHYKRDIFPARYGKFLALLDVNKRELEYERQSPFHAVRLHLLPTIRYPIYGLNATIWDTPDTNHSGYIYMDILERYARMDFNLTEDASQNLQMVGYIPDTRSAFLDIWRNYEEIRVIDVSSYLKMNHSRLITGRFHWRPSIRQEVREKIQAVGKSVYSSFSEGIDFWIKSIYTETTESMGVVWNTAKEYNRDFIDDIGQLSVLEEDLADLRLFVNQSYEANDFYIKNVVNFTLTILDELAIRDHIESLPKIFSELWQAMGDSGKALRNSIVWLIETIKTTYNNLLDAVARFFHGESLVYISGLLEKGIAKYDSFIKDLHIKFIKYIENLWHKTWTLAENHWKAVLKRFEPHLFKMISFIETTAWNLSKEVFDFIYKRTNELAESPYFNKVSSFTADAERLYRDFKANDAITNIKKYSTIAWNFVKEKYFKLVPFGAELNEVLTEIWQEIKELEKIDQVQIMVQKYYEVMAKVDWVADELQLEHRLHQVYGLVRNKFRNYAMNALETADMYREAKTKFVFDPEVGIIDLEQKLPMSWHAFNETPRFEEIPEYQVLAKAQSFFSETNSSIVMKLYNMRTHLDPKTWLPPYYSRALLIDSRHYMTFDQRYVGLNLNFDELGNGRSTSQCSYLLAHDFFKRNFTLLLEPASKSLAGQGLTRKLSFIANGQLIEIDLETDHISINGNPQPILPLKLGDVNIHRDLDVLSITSDTEFSLHCNVQFDLCWFEVSGWYFGRTAGLLGTLNNEPYDEYTMSSGVISNETQLFTDSWSLKQCRQNKLAQTQEVSQEVSDACTSFFRTGILATCSAVLDPTPFYEMCMDLGMKSPPIRKGHPAVKGACAAALAYIEACTALKVPMRVPSQCVFCQLSNGSYVPEGTFMELSGPEIPKSSDVVFIVEAKECNANLKTSKNIMTVVSSIEEQLQAAKITNNRYAVVAFGGVSPYDKARSVIYEHNEFTSKPEQLADYFGHINTGNGSSNDILMAISAAAKLNFRPGVSKTFILLSCSKCAARDMRFDYTSILQYLLEEGVNLHILADTEFDFERNKKLRHFFGLDSKLVYSKRFPEGDAETRNTTHIPKSNLGICTTLAVETQGSVFSARKLQPERKYPIKRFATIFAKRVALSATPIQSQTCECSAHNTGVSYMACSPQALPEEKYDLDDYDSFNNWDWGDEPESETNVMS", "length": 4333 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050411-73", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050411-73#orthology", "database": "AGR" }, { "id": "FB:FBgn0032136", "url": "https://alliancegenome.org/gene/FB:FBgn0032136#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7TMA5-1", "protein_name": "Apolipoprotein B-100", "gene_name": "Apob", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPQRPALRAPLLLLFLLLFLDTSVWAQDATRFKHLRKYVYSYEAESSSGVRGTADSRSATKINCKVELEVPQVCTLIMRTSQCTLKEVYGFNPEGKALMKKTKNSEEFASAMSRYELKLAFPEGKRVALYPDLGEPNYILNIKRGIISALLVPPETEEDKQVLFQDTVYGNCSTQVTVNSRKGTVATEMSTERNLQHCDGFQPISTSVSPLALIKGLVRPLSTLISSSQSCQYTLEPKRKHVSEAICNEQHLFLPFSYKNKYGIMTHVTQKLSLEDTPKINSRFFRGGINQVGLAFESTKSTSPPKQADAVLKTLQELKKLSISEQNAQRANLFHKLVTELRGLSGEAITSLLPQLIEVSSPITLQALIQCGQPECYTHILQWLKTEKAHPLLIDIVTYLMALIPNPSVQRLQEIFNTAKELQSRATLYALSHAVNSYYAIMDHSRSPVLEDIAGYLMKQIDNECMGDEDRTFLILRVIGNMGRTMERVMPALKSSVLNCVRSTKPSLQIQKAALQALRKMEMGDEVRTILFDTFVNDVAPVEKRLAAYLLLMRSPSSSDINKIAKLLQWEQSEQVKNFVASHIANILNSEELYVQDLKNLIKNALVNSRLPTIMDFRKFSRNYQISKSVSIPLFDPVSAKIEGNLVFDPSSYLPKESMLKTTLTVFGIASLDLFEIGLEGKGFEPTLEALFGKQGFFPDSVNKALYWVNGQVPDRVSKVLVDHFGYTKDDKHEQDMVNGIMPIVDKLIKELKSKEIPEARAYLRILGKELGFVRLQDLQVLGKLLLNGAQTFRGVPQMIVQAIREGSKDDLFLHYIFMENAFELPTGVGLQLQVSSSGVFTPGIKAGVRLELANIQAELVAKPSVSLEFVTNMGIIIPDFAKSGVQMNTNFFHESGLEARVALKAGQLKVIIPSPKRPVKLFSGSNTLHLVSTTKTEVIPPLIENRKSWSTCKPFFTGMNYCTTGAYSNASSTESASYYPLTGDTRYELELKPTGEVEQYSASATYELLKEDKSLVDTLKFLVQAEGVQQSEATAMFKYNRRSRTLSSEVLIPGFDVNFGTILRVNDESSKDKNTYKLILDIQNKKITEVSVVGHVSYDKKGDGKVKGVVSIPRLQAEARSEVHTHWSPTKLLFQMDSSATAYGSTISKRVAWRYDNEKIEFDWNTGTNVDTKKVASNFPVDLSRYPRMVHEYANGLLDHRVPQTDMTFRHMGSKLIVDHLNGLSELNLPKVGLPDFHIPDNLFLKTDGRVKYTLNKNRIEIDIPLPLGGKSSKDLKVPESVRTPALNFKSVGFHLPSQEVQIPTFTIPKTHQLQVPLLGILDLSTNVYSNLYNWSVSYTGGNTSRDHFSLQAQYRMKADSVVDLFSYSVQGSGETTYDSKSTFTLSCDGSLHHKFLDSKFKVSHVEKFGNNPVSKGLLTFETSSALGPQMSATVQLDSKKKQHLYVKDIKVDGQFRVFSLYAQGEYGLSYERDSMTGQMSGESNMKFNSTYFQGTNQIVGMYQDGMLSVTSTSDLQDGIFKNTASLKYENYELTLKSDSSGQYENFAASNKLDMTFSKQSALLRSEHQANYKSLRLVTLLSGSLTSQGVELNADILGTDKINTGAHKSTLKIAQDGVSTSATTNLKYSPLLLENELNAELGLSGASMKLSTSGRFKEHHAKFSLDGRAALTEVSLGSIYQAMILGADSKNVFNFKLSREGLKLSNDMMGSYAEMKLDHTHSLRISGLSLDFFSKMDNIYSGDKFYKQNFNLQLQPYSFGITLSNDLKYDALVLTNNGRLRLEPLKLNVGGNFKGTYQNNELKHIYTISYTDLVVASYRADTVATVQGVEFSHRLNADIEGLASSVDVTTSYSSDPLHFNNVFRFVLAPFTLGVDTHTSGDGKMSLWGEHTGQMYSKFLLKAEPLALTFSHDYKGSTSHNLLYKNSVSTALEHTLSALLTPAEQTSSWKFKTSLNDKVYSQEFEAYNTKDKIGIELSGRADLSGLYSPIKVPFFYSEPVNVLNSLEINDAFDEPREFTIDAVVKYDKNQDVHTISLPFFQSLPDYLERNRRGIISLLEAMKGELQRLSVDQFVRKYRVALSRLPQQIHDYLNASDWERQVAGAKEKLTSFMENYRITDNDVLIALDSAKINLNEKLSQLETYAIQFDQYIRDNYDAQDLKRTIAQIIDRIIEKLKMLDEQYHIRVNLAKSIHNLYLFVENVDLNQISSSGASWIQNVDTKYQIRIQIQEKLQHLRTQIHNIDIQQLAAELKQQIEALDVPMHLDQLRTAILFQRISVIIERVKYFVMNLIEDFKVTEKINTFRVIVRELIEKYEVDRQIQVLMDKSIELAHRYSLSEPLQKLSNVLQQIEIKDYYDKLVGFIDDTVEWIKAVSFKNIIEELNRLIDMSVKKLKAFDYHQFVDKTNSKIREMTQRINAEIQALELPQKTEALKLWVEDFKTTVSNSLEKLKDTKVTVVVDWLQDGLAQIKAQFQDALEDVRDRIYQMDIQGELERCLSLVSQVYSTVVTYISDWWTLTAKNITDFAEQYSTQKWAESVKALVEQGFIVPEIQTFLGTMPAFEVSLHALQEANFQTPDFIVPLTDLRIPSIWINFKMLKNVKIPLRFSTPEFTLLNTFRVRSFTIDLLEIKAKIIRTIDQMLSSELQWPLPEVYLRDLEMVNISLARLSLPDFHVPEITIPEFTIPNVNLKDLQVPDLHIPEFQLPHLSCTTEIPAFGKLHSVLKIQSPLFILDASANIQNITTSENKAEIVASVTARGESKFEALNFDFQAQAQFLELNANPLVLKESVNFSSKHVRMEHEGKILVSGKALEGKSDTVARLHTEKNTVEFNNGIVVKINNQFTLDSQTKYFHKLSVPRLDFSSKASLNNEIKTLLEAGHMAWTSSGTGSWNWACPNFSDEGIHSSKISFIVDGPIASFGLSNNINGKHLRVVQKLTSESGFLNYSRFEVESKVESQHVGSSILTAEGRALLGDAKAEMTGEHNANLNGKVIGTLKNSLFFSAQPFEITASTNNEGNLKVSFPLKLTGKIDFLNNYALFLSPHAQQASWQLSTRFNQYKYNQNFSAINNEHNMEASIVMNGDANLDFLNIPLTIPEINLPYTRFTTPLLKDFSIWEETGLKEFLKTTKQSFDLSIKAQYKKNRDKHSVVIPLKMFYEFMLNNVNSWDRKFEKVRDNALHFLTASYNETKIKFDKYKTENSLNQPSRTFQNRGHTIPVLNIEVSPFAVETLASSHVIPKAIRTPSVTIPGPNIIVPSYRLVLPSLQLPVFHIPRTLFKFSLPDFKKLSTIDNIYIPAMGNFTYDFSFKSSVITLNTNAGLYNQSDLVARFLSSSSFVTDALQYKLEGTSRLMRKKVLKLATAVSLTNKFLKGSHDSTISLTKKNMEASVKTTANLHAPIFTMNFKQELNGNTKSKPTVSSSIELNYDFNSSKLHSAAKGGVDHKFSLESLTSYLSIESFTKGNIKGSFLSQEYSGSVANEANVYLNSKGTRSSVRLQGASNFAGIWNFEVGENFAGEATLRRIYGTWEHNMINHLQVFSYFDTKGKQTCRATLELSPWTMSTLLQVHVSQPSPLFDLHHFDQEVILKASTKNQKVSWKSEVQVESQVLQHNAHFSNDQEEVRLDIAGSLEGQLWDLENFFLPAFGKSLRELLQIDGKRQYLQASTSLHYTKNPNGYLLSLPVQELTDRFIIPGLKLNDFSGIKIYKKLSTSPFALNLTMLPKVKFPGVDLLTQYSKPEGSSVPTFETTIPEIQLTVSQFTLPKSFPVGNTVFDLNKLTNLIADVDLPSITLPEQTIEIPSLEFSVPAGIFIPFFGELTAHVGMASPLYNVTWSTGWKNKADHVETFLDSTCSSTLQFLEYALKVVGTHRIENDKFIYKIKGTLQHCDFNVKYNEDGIFEGLWDLEGEAHLDITSPALTDFHLHYKEDKTSVSASAASPAIGTVSLDASTDDQSVRLNVYFRPQSPPDNKLSIFKMEWRDKESDGETYIKINWEEEAAFRLLDSLKSNVPKASEAVYDYVKKYHLGHASSELRKSLQNDAEHAIRMVDEMNVNAQRVTRDTYQSLYKKMLAQESQSIPEKLKKMVLGSLVRITQKYHMAVTWLMDSVIHFLKFNRVQFPGNAGTYTVDELYTIAMRETKKLLSQLFNGLGHLFSYVQDQVEKSRVINDITFKCPFSPTPCKLKDVLLIFREDLNILSNLGQQDINFTTILSDFQSFLERLLDIIEEKIECLKNNESTCVPDHINMFFKTHIPFAFKSLRENIYSVFSEFNDFVQSILQEGSYKLQQVHQYMKAFREEYFDPSVVGWTVKYYEIEEKMVDLIKTLLAPLRDFYSEYSVTAADFASKMSTQVEQFVSRDIREYLSMLADINGKGREKVAELSIVVKERIKSWSTAVAEITSDYLRQLHSKLQDFSDQLSGYYEKFVAESTRLIDLSIQNYHMFLRYIAELLKKLQVATANNGLLKRGDFEAAVKLGIACLYNEGLSVSDEAYAEVNGLKASRFFSMDERLNMGSDPFIWLSICPPCFRKLRDFAGKGCWEAQPALAKDCAGGSQLGLEGKAFSESVCQLFQASQAVNKQQIFSVQKGLSDTVRYILIGWLVEVAPMKDFTSLCLHLTVECVGRYLQRKLVPRYKLQLLGIACMVICTWFISKEILTIREAVRLTDNTYKYKDLVRVKREIISALEGKIRIPTVVDYKEVLLTLVPVTPRTQYLCSFLCELTLSVYTPAHLASAALLLARLMHGQTQP", "length": 4743 }, "evidence": [ { "id": "FB:FBgn0032136", "url": "https://alliancegenome.org/gene/FB:FBgn0032136#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9V496-1", "protein_name": "Apolipophorins", "gene_name": "apolpp", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARMKYNIALIGILASVLLTIAVNAENACNLGCPKSDNGLLKYIPGNYYDYSFDSILTIGASSDVPNDSDDTSLKVSGSAKIFAKGNCGYTLQLSSVKVTNTKESVEKKILNSIQKPVQFTLVSGILEPQICSDSSDLDYSLNIKRAVVSLLQSGIEAEHEVDVFGMCPTHTSTSKVGNANIITKARNLNSCSHREQINSGLVSGKVNEKAGITSSLLLQANYIKESRIVNHLIENVQLTETYKFIGNTKRNSDISAKVVTILKLKNPSGTKANSPGTGSTVRSLIFQRPETYTSKNINALKTILSDLVDSTGDYVKKETAKKFVEFIRLLRQSDSETLLELAAFPHPNKVLARKVYLDGLFRTSTAESARVILKQLSKFDEKEKLLAILSLNIVKSVDKETLNQAASQLLPNAPKELYIAVGNLVAKYCLKNYCQGPEIDAISKKFSDGLKHCKPNTKREEERIVYILKGLGNAKSLSGNTVAALSECASTGRSNRIRVAALHAFSKVKCEETLQSKSLELLKNRNEDSELRIEAYLSAISCPNAEVANQISEIVNSETVNQVGGFISSNLKAIRDSTDVSRDQQKYHLANIRVTKTFPVDYRRYSFNNEVSYKLESLGVGASTDYQIIYSQHGFLPRSSRINVTTEFFGTNYNVFEASVRQENVEDVLEYYLGPKGLVNKDFDEIVKLIEVGNNGVAAGGRARRSIVDDVSKISKKYKMYGVKNVQDLNLDVSLKLFGSELAFLSLGDNIPSSLDDIINYFSTSFEKAKQELSSFEKQFSSHHLFLDTDLAYPTSIGVPLELVAQGFAATKVDLAVSLDINAILEQNWQKAKYRLKFVPSVDINANVQIGFNAQVLSTGLRVVSSAHSATGSDITVAVISDGEGFNVDLELPREKLELINFNVDTELYVAEQDKQKAIALKGNKKNKNSQPSEICFNQLELVGLNICIKSSTSLSEVQAGNGNVAERGLSVSEKFHLSRPFNFAVYLTTERKFTFKGIHTQEAFSQKWKLDYSTPGSKVSHDTTVVYELGNKPKTFSRLSFDNSQCHFAVEGGINNDKNELVVYGQYEQDKEIKKSKIGFSKNGNEYKPLIEIQDNNGISNSINGYHADGKIVVKKNSNNIERYNFENFQVSNSNNAHVAVNGWSDVGTNSLTSELRISLDHQTFLIKENLKLENGLYEAGFFINDEHSPENIYGSSIHLTIADQSYALKTNGKAAAWSIGSDGSFNFQKLADSNSARAGSLVENVEIQYKNKQVGGIKIMSNFDVNKMDVDVEISREQKIGSIIVKYESNQRHAQDYSLEASAKINKHSIDVISKCDFNGNVYVVDNSLVTSWGTLLSAKGEIGQRYSAQDININIQGNVQISGKDKVTQWILKVIGTPDKTNSDFRISRDTSELIKLTSESQHPQDKISFAKLNLIVKNQLTAKGEFRVAKNGKGDFTASIDTLKTEPKHKLEIESKFHIQSPKYDIDASLTLDGKRKVHLKSENTIEKLKFSTKNIGEANDKIIAFEANGSLKGELRGNGEIQGTFIFNAPDGRVIDGSINRKISTNAKSGLSQGNIDAQLSDTPFGSNKKRSISLIGKLDRLNTKTKEFSANSNLVYTAFNGEKSEISYQIKQQPNGDAKNIDFSLKAYGNPLPQPFEIAFALGDYSAQHAVVSITSKYGEIFSVSANGNYNNNQALEYGLQANIEIPKSTLKSLEINSHGKVLKSLIGNENAAYNVEFFLDSKTSLGQYARVNTVWNGTANDGSYDFEAQTNNMESPLKFNGKYHRKQTGNIKDGDLTGKQTYVLNAQYGAQYVKMDASLGYGAEKVDIAYVIDSSFDSVKDIKVNIRTFKPLDDSTYVVTALFKQTDKSYGLDTTFYHSAHKKGVDIRLDLLKEKPIIISSIAELLGDRKGKVLFEILNLADLDIKINSEASYVSIDEFYIIVNWSSKKLKLDGYELEARAQSKNIKIQLKNENGIIFSGTATYALKKELNKTIIDGQGKVQYQGKALSGNFKLTRQHFDFGTDREVGFSYTFMGNLGSKNGLGTLKITNKEFNTKFSVCEEKRQCTNLIVQSIVSIDEQKLDAVEHTTLIIVDLRDFGYPYEFELKSQNTRQGLKYQYHLDSFIITGNNFKYQFTANVQPTSSTIKLALPKRQILFETTQKIPADGSLFGRYEQTASFFIDKLQKPDDVARFSAIVDVTGTERVAFNANGKLKFEHPTIRPLSISGQLNGDVNQQIASAEVIFDIFRLPEQKVVGNSELRNSRSQNGFNIAYITTVKSAGLQFQYQINSNAAVDIEAHEYNIGLELNNGEIDVKAISFLNKEKFEISLSESNKHIIYIVGDFSKQNHYAKLNTKVQILDKNPIEITSEVQPNSAKIILKRQDFIDGTAEVKLGKEFKVDVIGSGKQLFNGRVALDATNFLQTNYFINEDHLNGFWHIVESEINKDSEYISENIKERLKKSRQVTDKIVKLAKEAGPDFSKLQGKLLDYKNDIVQELEADQSIAPIIDGIRTLFKKIAGIVDDINKAISEILEKAQKSIVDIYDKLQALWKDSLLKAWEDFIITVQKLISTLKTEFIKICTQSFKDLLSALEKYGPALKNYGKAIGEIVKPINDAAQEVIKIVVNAAEGVTHEFKQYVASLPSFESIRNEFNDKVKVLKLFEKATELTNSLFDQINILPQTPETSEFLQKLHDYLIAKLKQEHIDNEKYIEELGQLLIKAVRSIWVSIRSTYPGSSDHVIDFQSWIGSLTHSFDSLAVLPSILSFRSSILNCLLNENWDVVFNKKLLYSWIFFNDFELRGHVVDGKHIFTFDGLNFAYPGNCKYILAQDSVDNNFTIIGQLTNGKLKSITLIDREGSYFEVADNLALKLNGNLVEYPQHLSGLHAWRRFYTIHLYSEYGVGIVCTSDLKVCHININGFYTSKTRGLLGNGNAEPYDDFLLIDGTLAENSAALGNDYGVGKCTAIEFDNNQFKSSKRQEMCSELFGIESTLAFNFITLDSRPYRKACDIALAKVAEKEKEATACTFALAYGSAVKQINKWVLLPPRCIKCAGPAGQHDFGDEFTVKLPNNKVDVVFVVDINVTPGVLSNLIAPAINDIRESLRSRGFSDVQVGVIVFEETKRYPALLTSDGGKINYKGNVADVKLAGIKSFCDNCVEQIITEKRILDIYNSLKEIVKGIAPQADEKAFQLALDYPFRAGAAKSIIGVRSDSLEYKNWWKFVRAQLTGSITKFDGALIHLIAPVKGLSLEGVLSEKLIGFNSRLVATVDGKDSKKRTKLQFDNDMGIDFVLNNGGWVFATQNFEKLKASDQKKMLNQITSSLADTLFKTEIVSDCRCLPIHGLHGQHKCVIKSSTFVANKKAKSA", "length": 3351 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050411-73", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050411-73#orthology", "database": "AGR" }, { "id": "FB:FBgn0087002", "url": "https://alliancegenome.org/gene/FB:FBgn0087002#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid transporter activity", "id": "GO:0005319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005319", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PD97", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PD97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1011, "end_pos": 1013, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1092, "end_pos": 1094, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1239, "end_pos": 1241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1250, 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PDC0-1", "uniprot_ac": "A0A8M9PDC0", "uniprot_id": "A0A8M9PDC0_DANRE", "mass": { "chemical_mass": 24886.0, "monoisotopic_mass": 24886.0 }, "refseq": { "ac": "XP_021322479", "name": "tetranectin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322479" }, "gene_names": [ { "name": "clec3ba", "type": "recommended", "evidence": [ { "id": "A0A8M9PDC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC0" } ] }, { "name": "clec3ba", "type": "synonym", "evidence": [ { "id": "XP_021322479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322479" } ] } ], "protein_names": [ { "name": "Tetranectin", "type": "synonym", "evidence": [ { "id": "A0A8M9PDC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC0/entry#names_and_taxonomy" } ] }, { "name": "tetranectin", "type": "synonym", "evidence": [ { "id": "XP_021322479", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322479" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021322479.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322479" } ] } ], "disease": [ { "disease_id": "DOID:0070441", "recommended_name": { "id": "DOID:0070441", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070441", "name": "retinal macular dystrophy 4", "description": "A retinal macular dystrophy characterized by late-onset macular degeneration, with multiple drusen-like deposits, macular geographic atrophy, and choroidal neovascularization that has_material_basis_in heterozygous mutation in the CLEC3B gene on chromosome 3p21." }, "synonyms": [ { "id": "DOID:0070441", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070441", "name": "MCDR4", "description": "" }, { "id": "MONDO:0859568", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0859568", "name": "macular dystrophy, retinal, 4", "description": "" }, { "id": "MIM:619977", "resource": "MIM", "url": "https://www.omim.org/entry/619977", "name": "Macular dystrophy, retinal, 4", "description": "Macular dystrophy, retinal, 4" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070441", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070441" } ] }, { "disease_id": "DOID:13300", "recommended_name": { "id": "DOID:13300", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13300", "name": "Scheuermann's disease", "description": "An osteochondrosis that results_in abnormal bone growth and curvature located_in thoracic vertebral column." }, "synonyms": [ { "id": "DOID:13300", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13300", "name": "Juvenile osteochondritis of the spine", "description": "" }, { "id": "DOID:13300", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13300", "name": "Juvenile osteochondrosis of Scheurermann", "description": "" }, { "id": "DOID:13300", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13300", "name": "Juvenile osteochondrosis of spine", "description": "" }, { "id": "DOID:13300", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13300", "name": "Scheuermann's kyphosis", "description": "" }, { "id": "DOID:13300", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13300", "name": "Sherman's Disease", "description": "" }, { "id": "MONDO:0008410", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008410", "name": "Scheuermann disease", "description": "A disorder characterized by osteochondrosis of the vertebral epiphyses in childhood." }, { "id": "MONDO:0008410", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008410", "name": "Calve's disease", "description": "" }, { "id": "MONDO:0008410", "resource": "MONDO", "url": 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"url": "https://monarchinitiative.org/disease/MONDO:0008410", "name": "juvenile kyphosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13300", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13300" } ] }, { "disease_id": "DOID:8398", "recommended_name": { "id": "DOID:8398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint." }, "synonyms": [ { "id": "DOID:8398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8398", "name": "Osteoarthrosis and allied disorder", "description": "" }, { "id": "DOID:8398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8398", "name": "degenerative arthritis", "description": "" }, { "id": "DOID:8398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8398", "name": "degenerative joint disease", "description": "" }, { "id": "DOID:8398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8398", "name": "hypertrophic arthritis", "description": "" }, { "id": "DOID:8398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8398", "name": "osteoarthrosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDC0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "clec3ba", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110411-71", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-71", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PDC0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PDC0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd03596", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03596", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "572488", "url": "https://www.ncbi.nlm.nih.gov/gene/572488", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051663", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051663", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:572488", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:572488", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DGHWVDQ", "url": "https://omabrowser.org/oma/group/DGHWVDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PDC0", "url": "https://www.orthodb.org/?gene=A0A8M9PDC0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22799", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22799", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22799:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22799:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322479", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322479", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PDC0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110411-71", "url": "https://zfin.org/ZDB-GENE-110411-71", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFGLICTSSVLLCMFFSTGCTYAEEKMDLKAVKFLLCVICLVKSSPEQSLTKRKNGKKESNSAAIEELKKQIDQIIQDLNLLKEQQALQTVCLKGFKIPGKCFLVDTVKKDFHSANDDCIAKGGILSTPMSGHENDQLQEYVQQTVGPETHIWLGVNDMIKEGEWIDLTGSPIRFKNWESEITHQPDGGRTHNCAVLSSTANGKWFDEDCRGEKASVCQFNIV", "length": 223, "header": "tr|A0A8M9PDC0-1|A0A8M9PDC0_DANRE Isoform 1 of Tetranectin OS=Danio rerio OX=7955 GN=clec3ba PE=4 SV=2 CANONICAL=A0A8M9PDC0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PDC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC0/entry#A0A8M9PDC0-1", "sequence": { "sequence": "MFGLICTSSVLLCMFFSTGCTYAEEKMDLKAVKFLLCVICLVKSSPEQSLTKRKNGKKESNSAAIEELKKQIDQIIQDLNLLKEQQALQTVCLKGFKIPGKCFLVDTVKKDFHSANDDCIAKGGILSTPMSGHENDQLQEYVQQTVGPETHIWLGVNDMIKEGEWIDLTGSPIRFKNWESEITHQPDGGRTHNCAVLSSTANGKWFDEDCRGEKASVCQFNIV", "length": 223, "header": "tr|A0A8M9PDC0-1|A0A8M9PDC0_DANRE Isoform 1 of Tetranectin OS=Danio rerio OX=7955 GN=clec3ba PE=4 SV=2 CANONICAL=A0A8M9PDC0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:572488", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:572488", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7F0Y1-1", "protein_name": "Tetranectin", "gene_name": "clec3bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLRDGRFLLPLLLLTLFTHSSLQQQNTSKKKTPDKKDSESRVSAALEDLQQQISDIVEELNLLKEQQALQTVCLKGTKIHGKCFLADSMKKRYHTANEDCIAKGGILATPLSSAQNTQLYEYMRQSISADAEIWLGVNDMQTEGLWTDQTGSAIRYKNWKLPQPDGGSAQNCAVLTSGGKWLDESCREERASICEFNIV", "length": 200 }, "evidence": [ { "id": "MGI:104540", "url": "https://alliancegenome.org/gene/MGI:104540#orthology", "database": "AGR" }, { "id": "HGNC:11891", "url": "https://alliancegenome.org/gene/HGNC:11891#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1SRC8-1", "protein_name": "C-type lectin domain family 3 member B", "gene_name": "CLEC3B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MELWGPYLLLCLFSLLTQVTAETPTPKVKKPANAKKDAASPKILEELKTQLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFVQAKTFHEASEDCISRGGTLGTPKTGSENDALYEYLRQSVGAEAEVWLGFNDMADEGAWVDMTGGHIAYKNWETEITAQPDGGKVENCAALAGAANGKWFDKRCRDKLPYVCQFAIV", "length": 202 }, "evidence": [ { "id": "A0A8M9PDC0", "url": "https://omabrowser.org/oma/group/A0A8M9PDC0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P05452-1", "protein_name": "Tetranectin", "gene_name": "CLEC3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELWGAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV", "length": 202 }, "evidence": [ { "id": "MGI:104540", "url": "https://alliancegenome.org/gene/MGI:104540#orthology", "database": "AGR" }, { "id": "HGNC:11891", "url": "https://alliancegenome.org/gene/HGNC:11891#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110411-71", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-71#orthology", "database": "AGR" }, { "id": "A0A8M9PDC0", "url": "https://omabrowser.org/oma/group/A0A8M9PDC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43025-1", "protein_name": "Tetranectin", "gene_name": "Clec3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGFWGTYLLFCLFSFLSQLTAESPTPKAKKAANAKKDLVSSKMFEELKNRMDVLAQEVALLKEKQALQTVCLKGTKVNLKCLLAFTQPKTFHEASEDCISQGGTLGTPQSELENEALFEYARHSVGNDANIWLGLNDMAAEGAWVDMTGGLLAYKNWETEITTQPDGGKAENCAALSGAANGKWFDKRCRDQLPYICQFAIV", "length": 202 }, "evidence": [ { "id": "MGI:104540", "url": "https://alliancegenome.org/gene/MGI:104540#orthology", "database": "AGR" }, { "id": "HGNC:11891", "url": "https://alliancegenome.org/gene/HGNC:11891#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110411-71", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-71#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDC0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDC0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDC0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC0" } ], "pmid": "" }, { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDC0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PDC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC0" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 219, "start_aa": "Ile", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PDC4-1", "uniprot_ac": "A0A8M9PDC4", "uniprot_id": "A0A8M9PDC4_DANRE", "mass": { "chemical_mass": 34924.0, "monoisotopic_mass": 34924.0 }, "refseq": { "ac": "XP_009290306", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290306" }, "gene_names": [ { "name": "LOC556653", "type": "recommended", "evidence": [ { "id": "A0A8M9PDC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC4" } ] }, { "name": "LOC556653", "type": "synonym", "evidence": [ { "id": "XP_009290306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290306" } ] } ], "protein_names": [ { "name": "CAP-Gly domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PDC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_009290306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290306" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009290306", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290306" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDC4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC556653", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC4", "locus": {} } ], "crossref": [ { "id": "556653", "url": "https://www.ncbi.nlm.nih.gov/gene/556653", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000938", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000938", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556653", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556653", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WAVFTWA", "url": "https://omabrowser.org/oma/group/WAVFTWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PDC4", "url": "https://www.orthodb.org/?gene=A0A8M9PDC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF01302", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01302", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009290306", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009290306", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PDC4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MATYVLWSAVVWTFKSLLFTWRFFWVSPYCALKSAPQQRLDTDHKPQPKLTTEVKRPAETDVMKDKPENCAQRDRKSGLFKRLLSAEGEIRELKIEIANQRASWDMRFVELQRRQHDLRDQLTSEILVRTGMLYRDNDSEETNEVFTESGLENGVYTDECISGLRQTHQQKRLDMDLLGDGVEQKSLYGSQTSCQSRATSAMSNISVRSWRSGGGPHRVFVPHSPMDLKTGHRVRIMLPSGRICTGTLRYLGNMHNSPDHYLGVELEMADNGQHDGTYEGQRYFDCDPGYGAFVPFSKLLMAWE", "length": 304, "header": "tr|A0A8M9PDC4-1|A0A8M9PDC4_DANRE Isoform 1 of CAP-Gly domain-containing protein OS=Danio rerio OX=7955 GN=LOC556653 PE=4 SV=1 CANONICAL=A0A8M9PDC4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PDC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC4/entry#A0A8M9PDC4-1", "sequence": { "sequence": "MATYVLWSAVVWTFKSLLFTWRFFWVSPYCALKSAPQQRLDTDHKPQPKLTTEVKRPAETDVMKDKPENCAQRDRKSGLFKRLLSAEGEIRELKIEIANQRASWDMRFVELQRRQHDLRDQLTSEILVRTGMLYRDNDSEETNEVFTESGLENGVYTDECISGLRQTHQQKRLDMDLLGDGVEQKSLYGSQTSCQSRATSAMSNISVRSWRSGGGPHRVFVPHSPMDLKTGHRVRIMLPSGRICTGTLRYLGNMHNSPDHYLGVELEMADNGQHDGTYEGQRYFDCDPGYGAFVPFSKLLMAWE", "length": 304, "header": "tr|A0A8M9PDC4-1|A0A8M9PDC4_DANRE Isoform 1 of CAP-Gly domain-containing protein OS=Danio rerio OX=7955 GN=LOC556653 PE=4 SV=1 CANONICAL=A0A8M9PDC4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:556653", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556653", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 137, "end_pos": 139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PDC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDC4" }, { "id": "PS50245", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50245" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CAP-Gly", "eco_id": "ECO_0000259", "start_pos": 252, "end_pos": 295, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 137, "end_pos": 139 }, { "start_pos": 204, "end_pos": 206 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PDK0-1", "uniprot_ac": "A0A8M9PDK0", "uniprot_id": "A0A8M9PDK0_DANRE", "mass": { "chemical_mass": 22874.0, "monoisotopic_mass": 22874.0 }, "refseq": { "ac": "XP_021322564", "name": "coiled-coil domain-containing protein 106", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322564" }, "gene_names": [ { "name": "LOC100147949", "type": "recommended", "evidence": [ { "id": "A0A8M9PDK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK0" } ] }, { "name": "LOC100147949", "type": "synonym", "evidence": [ { "id": "XP_021322564", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322564" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 106", "type": "synonym", "evidence": [ { "id": "A0A8M9PDK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK0/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 106", "type": "synonym", "evidence": [ { "id": "XP_021322564", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322564" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322564", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322564" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDK0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100147949", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK0", "locus": {} } ], "crossref": [ { "id": "A0A8M9PDK0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PDK0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100147949", "url": "https://www.ncbi.nlm.nih.gov/gene/100147949", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100147949", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100147949", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR16477", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16477", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16477:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16477:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15794", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15794", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322564", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322564", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PDK0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVEKDKLMLMAQTIQTLKQERDFLRQTVLKLSNRGAKKVKKVLDTSTECSTSNTDEESMTSSSSSDSPDSDIPRKKRKSHKKTKRASRSKSTKHSTRATTPDDVLRRYNKVFNAYKKEGSISKACAKVGVDRNTLALTAVVAEIQLVDAEFYRSIPKFRTEEKLFDFAKRCLQSLTTDLKSVIENAKQERKLLPIKYKFR", "length": 200, "header": "tr|A0A8M9PDK0-1|A0A8M9PDK0_DANRE Isoform 1 of Coiled-coil domain-containing protein 106 OS=Danio rerio OX=7955 GN=LOC100147949 PE=4 SV=1 CANONICAL=A0A8M9PDK0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PDK0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK0/entry#A0A8M9PDK0-1", "sequence": { "sequence": "MVEKDKLMLMAQTIQTLKQERDFLRQTVLKLSNRGAKKVKKVLDTSTECSTSNTDEESMTSSSSSDSPDSDIPRKKRKSHKKTKRASRSKSTKHSTRATTPDDVLRRYNKVFNAYKKEGSISKACAKVGVDRNTLALTAVVAEIQLVDAEFYRSIPKFRTEEKLFDFAKRCLQSLTTDLKSVIENAKQERKLLPIKYKFR", "length": 200, "header": "tr|A0A8M9PDK0-1|A0A8M9PDK0_DANRE Isoform 1 of Coiled-coil domain-containing protein 106 OS=Danio rerio OX=7955 GN=LOC100147949 PE=4 SV=1 CANONICAL=A0A8M9PDK0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100147949", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100147949", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDK0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PDM3-1", "uniprot_ac": "A0A8M9PDM3", "uniprot_id": "A0A8M9PDM3_DANRE", "mass": { "chemical_mass": 92690.0, "monoisotopic_mass": 92690.0 }, "refseq": { "ac": "XP_021324903", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324903" }, "gene_names": [ { "name": "LOC101885280", "type": "recommended", "evidence": [ { "id": "A0A8M9PDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDM3" } ] }, { "name": "LOC101885280", "type": "synonym", "evidence": [ { "id": "XP_021324903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324903" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PDM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDM3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021324903", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324903" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021324903.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324903" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDM3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDM3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101885280", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDM3", "locus": {} } ], "crossref": [ { "id": "A0A8M9PDM3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PDM3", "database": "AlphaFoldDB", "categories": [] }, { "id": "101885280", "url": "https://www.ncbi.nlm.nih.gov/gene/101885280", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:101885280", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885280", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_021324903", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324903", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PDM3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IBP2", "url": "https://www.uniprot.org/uniprotkb/A0AC58IBP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IBP2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IBP2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIDTFMVEMENTKGKQTKKKIFFRKHHGLAAVLEEEDALFRARPAVKVNDKPGKSQLPRRNDRYQGLAVILDEEEDALFRASPAVKVPDTASQTPTPADISTGPQTGTVSETNVPSETATEETIAVEVSITPEPTPASQTGSSSKTEDSSEESTAVESSTTGEANTATQTGSSSETKDTCVTVSEESTAVESSNTGETTKDSQTGSVSETDMSETATEKTTAGETSTTTADESSTTSETTEGLKVPETATASKTPVENSTGPQTGRVSETDVTSETVTEETTTSSASSSETEDTCVTVTEESTASESRTTGEANTASQTASSSKTEDTSVTVTEESTASESRTTGEPHSASQTGTDSETNAPSETVTEETTAGESSTTSEDTTASQTGTVSETDDTSVAVTEESTANESSTIDETTSESQTDTLSDSDVTFQTVIETATDQDATNNGYEIDNILDIVNTVDLLSEERLLMIAKSAHDATSPIHRGRTLFQRRREYVKHSVMVTQRLHMRLPVPVSLQPILRLLALLGISLPLNPPVPTRLALHHKVSFPLRQSLRIMVSLRPGPHLKPPLTLSQPASQRLGLPQRQLLRITTILHLRMPTSMRLQLSLRLNLPLTLPITPMSLRPILLPKPLRLNRLEVPQRVSLTLKKSLRTPLKVRPAPPLEPPLPLRLSLSHSVRLPLSQLLRISLSMRPLLTSPQRQLLRVTTALYLRLPLPLRLQLSLRFLVPLIQPQRPALPLRPALPLRPGLPLLKPTVPLLSPGLPLLRPAVILLGLGRPLRPAVPLLSPGLPFLRPGLPPLRPVVPLRPVVPLRPAVPFLRPSVPFLTPAVPFLRQGLPLLRSGPPLRFMGLMRYLR", "length": 857, "header": "tr|A0A8M9PDM3-1|A0A8M9PDM3_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101885280 PE=4 SV=2 CANONICAL=A0A8M9PDM3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PDM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDM3/entry#A0A8M9PDM3-1", "sequence": { "sequence": "MNIDTFMVEMENTKGKQTKKKIFFRKHHGLAAVLEEEDALFRARPAVKVNDKPGKSQLPRRNDRYQGLAVILDEEEDALFRASPAVKVPDTASQTPTPADISTGPQTGTVSETNVPSETATEETIAVEVSITPEPTPASQTGSSSKTEDSSEESTAVESSTTGEANTATQTGSSSETKDTCVTVSEESTAVESSNTGETTKDSQTGSVSETDMSETATEKTTAGETSTTTADESSTTSETTEGLKVPETATASKTPVENSTGPQTGRVSETDVTSETVTEETTTSSASSSETEDTCVTVTEESTASESRTTGEANTASQTASSSKTEDTSVTVTEESTASESRTTGEPHSASQTGTDSETNAPSETVTEETTAGESSTTSEDTTASQTGTVSETDDTSVAVTEESTANESSTIDETTSESQTDTLSDSDVTFQTVIETATDQDATNNGYEIDNILDIVNTVDLLSEERLLMIAKSAHDATSPIHRGRTLFQRRREYVKHSVMVTQRLHMRLPVPVSLQPILRLLALLGISLPLNPPVPTRLALHHKVSFPLRQSLRIMVSLRPGPHLKPPLTLSQPASQRLGLPQRQLLRITTILHLRMPTSMRLQLSLRLNLPLTLPITPMSLRPILLPKPLRLNRLEVPQRVSLTLKKSLRTPLKVRPAPPLEPPLPLRLSLSHSVRLPLSQLLRISLSMRPLLTSPQRQLLRVTTALYLRLPLPLRLQLSLRFLVPLIQPQRPALPLRPALPLRPGLPLLKPTVPLLSPGLPLLRPAVILLGLGRPLRPAVPLLSPGLPFLRPGLPPLRPVVPLRPVVPLRPAVPFLRPSVPFLTPAVPFLRQGLPLLRSGPPLRFMGLMRYLR", "length": 857, "header": "tr|A0A8M9PDM3-1|A0A8M9PDM3_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101885280 PE=4 SV=2 CANONICAL=A0A8M9PDM3-1" }, "locus": {} }, { "isoform_ac": "A0AC58IBP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDM3/entry#A0AC58IBP2-1", "sequence": { "sequence": "MSETATEKTTAGETSTTTADESSTTSETTEGLKVPETATASKTPVENSTGPQTGRVSETDVTSETVTEETTTSSASSSETEDTCVTVTEESTASESRTTGEANTASQTASSSKTEDTSVTVTEESTASESRTTGEPHSASQTGTDSETNAPSETVTEETTAGESSTTSEDTTASQTGTVSETDDTSVAVTEESTANESSTIDETTSESQTDTLSDSDVTFQTVIETATDQDATNNGYEIDNILDIVNTVDLLSEERLLMIAKSAHDATSPIHRGRTLFQRRREYVKHSVMVTQRLHMRLPVPVSLQPILRLLALLGISLPLNPPVPTRLALHHKVSFPLRQSLRIMVSLRPGPHLKPPLTLSQPASQRLGLPQRQLLRITTILHLRMPTSMRLQLSLRLNLPLTLPITPMSLRPILLPKPLRLNRLEVPQRVSLTLKKSLRTPLKVRPAPPLEPPLPLRLSLSHSVRLPLSQLLRISLSMRPLLTSPQRQLLRVTTALYLRLPLPLRLQLSLRFLVPLIQPQRPALPLRPALPLRPGLPLLKPTVPLLSPGLPLLRPAVILLGLGRPLRPAVPLLSPGLPFLRPGLPPLRPVVPLRPVVPLRPAVPFLRPSVPFLTPAVPFLRQGLPLLRSGPPLRFMGLMRYLR", "length": 645, "header": "tr|A0AC58IBP2-1|A0AC58IBP2_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC101885280 PE=4 SV=1 CANONICAL=A0A8M9PDM3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 136, "start_aa": "Thr", "end_pos": 136, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr136", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" }, { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T408 is on non-canonical isoform A0AC58IBP2-1 which maps to canonical isoform site A0A8M9PDM3-1:620", "icn3d_view": {}, "start_pos": 620, "start_aa": "Thr", "end_pos": 620, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr620", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 97, "start_aa": "Thr", "end_pos": 97, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr97", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101885280", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885280", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 97, 136, 620 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 259, "end_pos": 261 }, { "start_pos": 408, "end_pos": 410 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PDT7-1", "uniprot_ac": "A0A8M9PDT7", "uniprot_id": "A0A8M9PDT7_DANRE", "mass": { "chemical_mass": 61996.0, "monoisotopic_mass": 61996.0 }, "refseq": { "ac": "XP_021322664", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322664" }, "gene_names": [ { "name": "LOC100006870", "type": "recommended", "evidence": [ { "id": "A0A8M9PDT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDT7" } ] }, { "name": "LOC100006870", "type": "synonym", "evidence": [ { "id": "XP_021322664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322664" } ] } ], "protein_names": [ { "name": "C-type lectin domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PDT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDT7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021322664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322664" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021322664.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322664" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PDT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDT7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100006870", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDT7", "locus": {} } ], "crossref": [ { "id": "A0A8M9PDT7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PDT7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100006870", "url": "https://www.ncbi.nlm.nih.gov/gene/100006870", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035234", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035234", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100006870", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006870", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PDT7", "url": "https://www.orthodb.org/?gene=A0A8M9PDT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322664", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PDT7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDT7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLAILLMASMFCQGLSLVSYGDSFITAFPENLGFFYPFPLWNILKVTALYDNTKITILRTNSQQDFTIQKSGQTLRVYVSNVEVNQLGFWDLSVRVTSDKNITLVSVSQRGMSTQVNVIQPIVNLGTDYWIPLLDYPGYLETFKLPSLVSTDMRYSSFKLLIINAVNSQNNIIVVKKTSTDVEEETFSIDPYKLVQLQTNGSVLRVKSSSKVAVILTHPCVETADCNCNMIMNQILPAELQGQSFIVPSVFNVTKTMLLFTSENASTYFQNGNQFQASPSALVAFSDLQVSQLVNVSDRVSIRLISPGLVVEMISENSFSACFLLQFNGPNGQAVVIAETDSKDQVSTDSGILQASEWTAIAGTIYSSTVVTIPVQYATIWHPTSKIAVYMLEQMAAKIFYGCLALPICEKPDLHGCVLAPGTYIIGPDLLNWTKSREYCVDNVNQFACPLSKSILKDMADTLSAGDGQGWIGLRRSLLTTEWYWQDEYASQTTLSFVHWDDGQPVDPSRGLRTSVSLDPTKGYKWKSGRCCDTKKPVCYKRPAYLIPTQDWLAMYI", "length": 557, "header": "tr|A0A8M9PDT7-1|A0A8M9PDT7_DANRE Isoform 1 of C-type lectin domain-containing protein OS=Danio rerio OX=7955 GN=LOC100006870 PE=4 SV=2 CANONICAL=A0A8M9PDT7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PDT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDT7/entry#A0A8M9PDT7-1", "sequence": { "sequence": "MLAILLMASMFCQGLSLVSYGDSFITAFPENLGFFYPFPLWNILKVTALYDNTKITILRTNSQQDFTIQKSGQTLRVYVSNVEVNQLGFWDLSVRVTSDKNITLVSVSQRGMSTQVNVIQPIVNLGTDYWIPLLDYPGYLETFKLPSLVSTDMRYSSFKLLIINAVNSQNNIIVVKKTSTDVEEETFSIDPYKLVQLQTNGSVLRVKSSSKVAVILTHPCVETADCNCNMIMNQILPAELQGQSFIVPSVFNVTKTMLLFTSENASTYFQNGNQFQASPSALVAFSDLQVSQLVNVSDRVSIRLISPGLVVEMISENSFSACFLLQFNGPNGQAVVIAETDSKDQVSTDSGILQASEWTAIAGTIYSSTVVTIPVQYATIWHPTSKIAVYMLEQMAAKIFYGCLALPICEKPDLHGCVLAPGTYIIGPDLLNWTKSREYCVDNVNQFACPLSKSILKDMADTLSAGDGQGWIGLRRSLLTTEWYWQDEYASQTTLSFVHWDDGQPVDPSRGLRTSVSLDPTKGYKWKSGRCCDTKKPVCYKRPAYLIPTQDWLAMYI", "length": 557, "header": "tr|A0A8M9PDT7-1|A0A8M9PDT7_DANRE Isoform 1 of C-type lectin domain-containing protein OS=Danio rerio OX=7955 GN=LOC100006870 PE=4 SV=2 CANONICAL=A0A8M9PDT7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100006870", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006870", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PDT7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDT7" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 419, "end_pos": 540, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 432, "end_pos": 434 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. 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Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325063", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325063" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE04", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE04#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE04", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE04" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "znf1159", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE04", "locus": {} } ], "crossref": [ { "id": "100034458", "url": "https://www.ncbi.nlm.nih.gov/gene/100034458", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100034458", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100034458", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PE04", "url": "https://www.orthodb.org/?gene=A0A8M9PE04", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24384", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24384", 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GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325083.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325083" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100536344", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19", "locus": {} } ], "crossref": [ { "id": "A0A8M9PE19", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PE19", "database": "AlphaFoldDB", "categories": [] }, { "id": "100536344", "url": "https://www.ncbi.nlm.nih.gov/gene/100536344", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100536344", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536344", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PE19", "url": "https://www.orthodb.org/?gene=A0A8M9PE19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325083", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PE19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PE19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTSPLTRSFRVESSELSSAAISERQRQSLLKDSEKMSDPEPCRIKQEETEELIDVIVKEESEELSEDEEKHHVKSEDETLVNTEHDVSVERTALECFTCTQCGKSLSSRCHLKRHMMIHSGERPHKCDQCSKSYLRASELKRHLSVHTTERPYSCSECGKSFRHPTHLKDHQKLHTAVRKFVCFKCKKTFTTAEYLKRHERIHLGEKPYECSVCDKRFRLASLLKFHQMTHTGERPFTCTQCGKSFTQLSHLREHMLVHTGERPHKCDQCDKTFFRSSELNKHRRVHTNERPYLCSECGKSFTLLSHLNGHQKIHAGVREHVCFVCGKTFIRVSDLRRHQKIHTGEKPYVCSHCDKAFRDSGYLKTHERTHTGEKPYTCAQCGRSFAQFAHLNRHLLVHTGEKSHE", "length": 406, "header": "tr|A0A8M9PE19-1|A0A8M9PE19_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC100536344 PE=4 SV=2 CANONICAL=A0A8M9PE19-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PE19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19/entry#A0A8M9PE19-1", "sequence": { "sequence": "MTSPLTRSFRVESSELSSAAISERQRQSLLKDSEKMSDPEPCRIKQEETEELIDVIVKEESEELSEDEEKHHVKSEDETLVNTEHDVSVERTALECFTCTQCGKSLSSRCHLKRHMMIHSGERPHKCDQCSKSYLRASELKRHLSVHTTERPYSCSECGKSFRHPTHLKDHQKLHTAVRKFVCFKCKKTFTTAEYLKRHERIHLGEKPYECSVCDKRFRLASLLKFHQMTHTGERPFTCTQCGKSFTQLSHLREHMLVHTGERPHKCDQCDKTFFRSSELNKHRRVHTNERPYLCSECGKSFTLLSHLNGHQKIHAGVREHVCFVCGKTFIRVSDLRRHQKIHTGEKPYVCSHCDKAFRDSGYLKTHERTHTGEKPYTCAQCGRSFAQFAHLNRHLLVHTGEKSHE", "length": 406, "header": "tr|A0A8M9PE19-1|A0A8M9PE19_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC100536344 PE=4 SV=2 CANONICAL=A0A8M9PE19-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100536344", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536344", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19" } ], "pmid": "" }, { "name": "RNA polymerase II transcription regulatory region sequence-specific DNA binding", "id": "GO:0000977", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000977", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PE19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PE19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PE19" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 97, "end_pos": 124, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PEE2-1", "uniprot_ac": "A0A8M9PEE2", "uniprot_id": "A0A8M9PEE2_DANRE", "mass": { "chemical_mass": 30154.0, "monoisotopic_mass": 30154.0 }, "refseq": { "ac": "XP_021325218", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325218" }, "gene_names": [ { "name": "LOC137487213", "type": "recommended", "evidence": [ { "id": "A0A8M9PEE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEE2" } ] }, { "name": "LOC137487213", "type": "synonym", "evidence": [ { "id": "XP_021325218", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325218" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PEE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEE2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021325218", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325218" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325218" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEE2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC137487213", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEE2", "locus": {} } ], "crossref": [ { "id": "A0A8M9PEE2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PEE2", "database": "AlphaFoldDB", "categories": [] }, { "id": "137487213", "url": "https://www.ncbi.nlm.nih.gov/gene/137487213", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:137487213", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:137487213", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PEE2", "url": "https://www.orthodb.org/?gene=A0A8M9PEE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_021325218", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325218", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PEE2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PEE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEE2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLWSFGAENTLIAKINIKEQIFSTFDGTDRFRDRLKMDRQTGSLTITNITSENAGIYNLDISGKKWPSKIFNVSVHARLLVPALIFNSSLCSSSQYNYSVVCSVVNVSAVSLSWYKGNSVLSSISVSDLSISLSLPLEVEYQDNNTYSCVINNTISNQTTHLDINTLCQPCEGSQIVLISAAAGSLMTFVGVGIFWICWKCGNSDQKGKCYISVTYMILKPVINPHGKKIYGLYMHLNFAYMWHIYTYVHKGSYICIYPHLGPFHVEIF", "length": 269, "header": "tr|A0A8M9PEE2-1|A0A8M9PEE2_DANRE Isoform 1 of Ig-like domain-containing protein OS=Danio rerio OX=7955 GN=LOC137487213 PE=4 SV=1 CANONICAL=A0A8M9PEE2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PEE2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEE2/entry#A0A8M9PEE2-1", "sequence": { "sequence": "MLWSFGAENTLIAKINIKEQIFSTFDGTDRFRDRLKMDRQTGSLTITNITSENAGIYNLDISGKKWPSKIFNVSVHARLLVPALIFNSSLCSSSQYNYSVVCSVVNVSAVSLSWYKGNSVLSSISVSDLSISLSLPLEVEYQDNNTYSCVINNTISNQTTHLDINTLCQPCEGSQIVLISAAAGSLMTFVGVGIFWICWKCGNSDQKGKCYISVTYMILKPVINPHGKKIYGLYMHLNFAYMWHIYTYVHKGSYICIYPHLGPFHVEIF", "length": 269, "header": "tr|A0A8M9PEE2-1|A0A8M9PEE2_DANRE Isoform 1 of Ig-like domain-containing protein OS=Danio rerio OX=7955 GN=LOC137487213 PE=4 SV=1 CANONICAL=A0A8M9PEE2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:137487213", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:137487213", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PEE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEE2" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": 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factor HIVEP2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158638" }, "gene_names": [ { "name": "hivep2b", "type": "recommended", "evidence": [ { "id": "A0A8M9PEH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH8" } ] }, { "name": "hivep2b", "type": "synonym", "evidence": [ { "id": "XP_005158638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158638" } ] } ], "protein_names": [ { "name": "Transcription factor HIVEP2", "type": "synonym", "evidence": [ { "id": "A0A8M9PEH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH8/entry#names_and_taxonomy" } ] }, { "name": "transcription factor HIVEP2", "type": "synonym", "evidence": [ { "id": "XP_005158638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158638" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005158638", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005158638" } ] } ], "disease": [ { "disease_id": "DOID:0050787", "recommended_name": { "id": "DOID:0050787", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050787", "name": "juvenile polyposis syndrome", "description": "A gastrointestinal system disease that is characterized by predisposition to hamartomatous benign polyps in the gastrointestinal tract, specifically in the stomach, small intestine, colon, and rectum." }, "synonyms": [ { "id": "MONDO:0017380", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0017380", "name": "juvenile polyposis syndrome", "description": "Juvenile gastrointestinal polyposis (JIP) is a rare condition characterized by the presence of juvenile hamartomatous polyps in the gastrointestinal (GI) tract." }, { "id": 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"https://www.omim.org/entry/174900", "name": "Juvenile polyposis syndrome", "description": "Juvenile polyposis syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050787", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050787" } ] }, { "disease_id": "DOID:0070073", "recommended_name": { "id": "DOID:0070073", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070073", "name": "autosomal dominant intellectual developmental disorder 43", "description": "An autosomal dominant intellectual developmental disorder characterized by delayed psychomotor development with impaired intellectual development and poor speech, hypotonia, and nonspecific dysmorphic features that has_material_basis_in an autosomal dominant mutation of the HIVEP2 gene on chromosome 6q24.2." }, "synonyms": [ { "id": "DOID:0070073", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070073", "name": "MRD43", "description": "" }, { "id": "DOID:0070073", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070073", "name": "autosomal dominant mental retardation 43", "description": "" }, { "id": "DOID:0070073", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070073", "name": "autosomal dominant non-syndromic intellectual disability 43", "description": "" }, { "id": "MONDO:0014858", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014858", "name": "intellectual disability, autosomal dominant 43", "description": "Any autosomal dominant non-syndromic intellectual disability in which the cause of the disease is a mutation in the HIVEP2 gene." }, { "id": "MONDO:0014858", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014858", "name": "HIVEP2 autosomal dominant non-syndromic intellectual disability", "description": "" }, { "id": "MONDO:0014858", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014858", "name": "MRD43", "description": "" }, { "id": "MONDO:0014858", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014858", "name": "autosomal dominant intellectual disability 43", "description": "" }, { "id": "MONDO:0014858", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014858", "name": "autosomal dominant non-syndromic intellectual disability caused by mutation in HIVEP2", "description": "" }, { "id": "MONDO:0014858", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014858", "name": "intellectual disability, autosomal dominant 43", "description": "" }, { "id": "MONDO:0014858", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014858", "name": "intellectual disability, autosomal dominant type 43", "description": "" }, { "id": "MONDO:0014858", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014858", "name": "mental retardation, autosomal dominant 43", "description": "" }, { "id": "MONDO:0014858", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014858", "name": "mental retardation, autosomal dominant type 43", "description": "" }, { "id": "MONDO:0014858", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014858", "name": "HIVEP2-related intellectual disability", "description": "" }, { "id": "MONDO:0014858", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014858", "name": "autosomal dominant intellectual disability-43", "description": "" }, { "id": "MIM:616977", "resource": "MIM", "url": "https://www.omim.org/entry/616977", "name": "Intellectual developmental disorder, autosomal dominant 43", "description": "Intellectual developmental disorder, autosomal dominant 43" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070073" } ] }, { 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starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid." }, "synonyms": [ { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer disease", "description": "" }, { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimers dementia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ] }, { "disease_id": "DOID:2841", "recommended_name": { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing." }, "synonyms": [ { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "bronchial hyperreactivity", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with acute exacerbation", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with status asthmaticus", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "inherited susceptibility to asthma", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, nocturnal, susceptibility to", "description": "" }, { "id": "MIM:600807", "resource": "MIM", "url": "https://www.omim.org/entry/600807", "name": "Asthma", "description": "Asthma" } ], "unlinked_id_list": [ "DOID:0080811", "DOID:0080819" ], "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ] }, { "disease_id": "DOID:5419", "recommended_name": { "id": "DOID:5419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness." }, "synonyms": [ { "id": "DOID:5419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5419", "name": "schizophrenia-1", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality." }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia 12", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia (disease)", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "SCZD", "description": "" }, { "id": "MIM:181500", "resource": "MIM", "url": "https://www.omim.org/entry/181500", "name": "Schizophrenia", "description": "Schizophrenia" } ], "unlinked_id_list": [], "evidence": [ { "id": "5419", "database": "AGR", "url": 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"MEATKTSGEVESSEQIISFKDDEKHLPSEMTQRGQSSGSEDKIRLAEQPQTPSVSPSPGIEPQVLASGNTLTSKSKEQSHVQLRRKNVPLPNKRYLQAEYEMLSGGLHKKEQKSVKTGKYVCQYCGRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHTHAVKAGLVSVSEQDCKNTDEVAEGEMHSDAEQSSDTDEEVAEDLSLDTTSHIKETEGYVQEKVGKLAKKEALFPSQTPLKKETGPSGKVSLWQFREMTAPVAIAQIDQMVEFSTIKQKLALRLSEKKSQESDQSLSLPSSYSKGSTDSGYFSRSESAEQQINQSSASAKSYQEIMFGKCYRPATRPKQSITVQTCMTDINEATSSFMITLNKGMMPGDTDSSIHRSKKDLVRSIKIDSESFQEEDYQECQIPSSDLLETALESSVFLRSNSLPTSSKSNLNTPQGLRSSNSFDERMTGADVTYRGAMGMRRLMRQSAFEHSANEGHAESDCYTHLACSLKSDLKIHSIDDSKMAAENFQETETCSVCPGHSSESSTRKRRKDKTVTEEEDFHIQDKPSNVTGLSEDLETKQISSDSVVSDTERKAGSNVISVIQHTNSLNRLNSAEKLSEVRSHQLDKIGKFMEKGHSMECHRTGSECQWGPCGFLHQKLHMHKQPTSQPNIQVPEIRVTVEPDRPEKVPDVGVKQREKHTEEFQWPQRSETLSQFPMEKLPPKKKRLRLAEMECSSGESSFESACTSLSRSPSQDSNLSHSSSFSQSLDREETLNLVSQINPDESSKPLEFLSVPGSSQSHHREMRRSASEQAPYKLPSEIAEFRSKSFDYGSLSPSSTYRLEEVKERRRAFLVRQASLSGEPETQGGNFSDEISKRTTLPFTPEGSIEKMRYSLISGSSFPHHRQYSPVQSSSQHVKPTVCNVHDMENVMLVIKKEPEESKSPETYVNLREPQEDCSQSLGNVLSTIAVLSQAQQALASQCSSGLLVPVRIQMQVPSYGNITYTSISHILDSHIQKPISCLEHKKSSSQSQQLHSLQASPAKLKTGIPLSLTSKTISTTEAPSGGANKRMLSPASSIELFIEAKQQKRVKDENIYGQIVEELSAVELGNLEVEKESPKSEFTSEPIDKMDMDEATQEFYSNAELQSSARISQDAAIMEQKPTPESMMASHHSASCISLMPSAITGTLLFSKFPGLHTTTCMSWCYLNTTKPNSTHTVAPFSEYASWFVRCHNPNPPDISTGMVLALLRSKQQRQNAIYTIATIYQPGLLVTSTPWTPKQEQIALDYREEDTKQDIRLREISHRGKSLREDVSSIIRQTEPMRVKIFEGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHTDVRPYICKCCNFAFKTKGNLTKHMKSKAHMKKCLELGVSPTAMDNTEDADDTQKSLGIMPAEQTIKHQFSDVEDSDGADEDEPDEDEDDECDGDSTPKTLSRSTSPQSYAVNKPCMSGCLPKHFDSGCNLPKEQLEASSLTIEDDLNSDQSSCSFELCPPQLLSPCWDSPRQRYMSPRGDLSPQRHLLSSRDSSPLRAVSPRRDLSIRGDFSPIRQLSPVRPTGLDTSGQRAQSPLGRHKVALRAVSPRRGSYQHRTHMDLGRSVRFQASPIRPIIGETGVDQGDTSLNLIVPVGLCSSKDLPKTRQPDIFSHLPLHSQGQVSTPVPMVPIGVLRMPSISTSGAVAERNSLPSIPQGNILETAAPGQTSASVPDPAVAYSGEIATYSTGLPNKDDKKEESVYTCAKAIASLRITSEDASDNPPKS", "length": 1798, "header": "tr|A0A8M9PEH8-1|A0A8M9PEH8_DANRE Isoform 1 of Transcription factor HIVEP2 OS=Danio rerio OX=7955 GN=hivep2b PE=4 SV=1 CANONICAL=A0A8M9PEH8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PEH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH8/entry#A0A8M9PEH8-1", "sequence": { "sequence": "MEATKTSGEVESSEQIISFKDDEKHLPSEMTQRGQSSGSEDKIRLAEQPQTPSVSPSPGIEPQVLASGNTLTSKSKEQSHVQLRRKNVPLPNKRYLQAEYEMLSGGLHKKEQKSVKTGKYVCQYCGRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHTHAVKAGLVSVSEQDCKNTDEVAEGEMHSDAEQSSDTDEEVAEDLSLDTTSHIKETEGYVQEKVGKLAKKEALFPSQTPLKKETGPSGKVSLWQFREMTAPVAIAQIDQMVEFSTIKQKLALRLSEKKSQESDQSLSLPSSYSKGSTDSGYFSRSESAEQQINQSSASAKSYQEIMFGKCYRPATRPKQSITVQTCMTDINEATSSFMITLNKGMMPGDTDSSIHRSKKDLVRSIKIDSESFQEEDYQECQIPSSDLLETALESSVFLRSNSLPTSSKSNLNTPQGLRSSNSFDERMTGADVTYRGAMGMRRLMRQSAFEHSANEGHAESDCYTHLACSLKSDLKIHSIDDSKMAAENFQETETCSVCPGHSSESSTRKRRKDKTVTEEEDFHIQDKPSNVTGLSEDLETKQISSDSVVSDTERKAGSNVISVIQHTNSLNRLNSAEKLSEVRSHQLDKIGKFMEKGHSMECHRTGSECQWGPCGFLHQKLHMHKQPTSQPNIQVPEIRVTVEPDRPEKVPDVGVKQREKHTEEFQWPQRSETLSQFPMEKLPPKKKRLRLAEMECSSGESSFESACTSLSRSPSQDSNLSHSSSFSQSLDREETLNLVSQINPDESSKPLEFLSVPGSSQSHHREMRRSASEQAPYKLPSEIAEFRSKSFDYGSLSPSSTYRLEEVKERRRAFLVRQASLSGEPETQGGNFSDEISKRTTLPFTPEGSIEKMRYSLISGSSFPHHRQYSPVQSSSQHVKPTVCNVHDMENVMLVIKKEPEESKSPETYVNLREPQEDCSQSLGNVLSTIAVLSQAQQALASQCSSGLLVPVRIQMQVPSYGNITYTSISHILDSHIQKPISCLEHKKSSSQSQQLHSLQASPAKLKTGIPLSLTSKTISTTEAPSGGANKRMLSPASSIELFIEAKQQKRVKDENIYGQIVEELSAVELGNLEVEKESPKSEFTSEPIDKMDMDEATQEFYSNAELQSSARISQDAAIMEQKPTPESMMASHHSASCISLMPSAITGTLLFSKFPGLHTTTCMSWCYLNTTKPNSTHTVAPFSEYASWFVRCHNPNPPDISTGMVLALLRSKQQRQNAIYTIATIYQPGLLVTSTPWTPKQEQIALDYREEDTKQDIRLREISHRGKSLREDVSSIIRQTEPMRVKIFEGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHTDVRPYICKCCNFAFKTKGNLTKHMKSKAHMKKCLELGVSPTAMDNTEDADDTQKSLGIMPAEQTIKHQFSDVEDSDGADEDEPDEDEDDECDGDSTPKTLSRSTSPQSYAVNKPCMSGCLPKHFDSGCNLPKEQLEASSLTIEDDLNSDQSSCSFELCPPQLLSPCWDSPRQRYMSPRGDLSPQRHLLSSRDSSPLRAVSPRRDLSIRGDFSPIRQLSPVRPTGLDTSGQRAQSPLGRHKVALRAVSPRRGSYQHRTHMDLGRSVRFQASPIRPIIGETGVDQGDTSLNLIVPVGLCSSKDLPKTRQPDIFSHLPLHSQGQVSTPVPMVPIGVLRMPSISTSGAVAERNSLPSIPQGNILETAAPGQTSASVPDPAVAYSGEIATYSTGLPNKDDKKEESVYTCAKAIASLRITSEDASDNPPKS", "length": 1798, "header": "tr|A0A8M9PEH8-1|A0A8M9PEH8_DANRE Isoform 1 of Transcription factor HIVEP2 OS=Danio rerio OX=7955 GN=hivep2b PE=4 SV=1 CANONICAL=A0A8M9PEH8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1414, "start_aa": "Thr", "end_pos": 1414, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1414", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100536055", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536055", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B7M4-1", "protein_name": "Transcription factor HIVEP2a isoform X1", "gene_name": "hivep2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEPHEPIVGQKCTKEQREKNPLQRKWVSEPSAGTKRNTFADPDIKRHSHREQSLTGGTNLTSSTQKYSSGNLMSSAVTHSSQEGQFQQIFPRPYPYQLPHSYPQEPFLGGTKPQPGLEAHAWSFSGQLQSLPPDDMYPVHSRSHGVFPRHKSPAGFGQFSQSGPEQPDESHKKEQKPKKPGKYICHYCGRACAKPSVLKKHIRSHTGERPYPCVPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFSDLATRTDTDQASSVGEAEAHSDGEQSTDTDEETAEGAMFPEKCSPQISFESDKSPMERGPAYADPAEELSVASMKVPILIVPKQGVPSPATECPQFTDIKGSVIGGQMGRGDESHTVKQRLALRLTEKKDLDSEQSQNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNVKTYEEIMFGRTWYHRTNSRSRQSVTVGMVAIASQDTNINKSSAMQELAMGKISEGHVFYQSDCAESHLIPGCDPKHYHAGSCQTSTGLLEAPSDSGPLIRSNSMPTPSPTNLNVPPNLRGSHSFDEMMTQDDVFYTGAAGLKRLRRQSAFEHSVQEGHGESESYGKITGPNSSLRGHLMPELKGSGSEMACPEVRTAYTSYGTKVGMTEFTTRKRRMKKSVGEEEDCLGQDDGSRSGSTEMAEEYDLRQGSQDSSKAVPANKGSMFRAHSPSDSFDRGSCMTPEDVVHVQDSDTKTGGNVISVIQHTNSLSRPNSFEKTESIEHPFYQPDKHAGHLSEQSDTENIDDVQSPDSHHRSESMEHQQQGDNEHGSFSSNTLYHMPHKLVRQPNIQVPEIRVTEEPDKPEKEPEVPAKEPEKHVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTCTSLSRSPSQESNLSHSSSFSMSFDREESIKSVSPTKQDEFAKQSEFLTVPGSGHSLSIPGHHQREMRRSSSEQAPSALPTEVPEIRSKSFDYGSLSTGSRQGEVYASASAMKERRRGYLVRQASLSVYPEVVVQEPISELSIKQEHSDHVSQAGLTGTSYCVANDLPRPRRGAQSVLGSHLLLQQSISEDSQSEDHFQNTPRLPAQLSSDSEHSVHEHMTQDLFQHSSLQSSMASSPFLPFQPMLWHPESTQRNKHNLAFQSHNLQKLHIKQPNLQPLLQKPYQPSHQIQVQTDSKTDGASHNYPYPSRASPQQLGVLSSKVLTTSFLQQVQPTFATQNVGSPQSLPGMLVPVRIQTNVPSYGSVMYTSVSQILVTHAQSTTSIRVICTDNVSTASITGTASKHQVGINLSKILGHSGGSINFPTWKVPEYLPGSLNTGIPLSLTSGTISTTDASSNIGGSKRMLSPASSLELFIETKQQKRVKEEKMYGQIVKELSAVELSNSSAPKDNESTKAEFSNRDDSIDEQERMSSSPPSDFLSSKYLGYPSAPRLPDVPPKDNFIPPLQIITNVTSRADSPEELDVDESTPEASSSPQSVMSSSDTQEESKQSMGNKFPVNMLVQLAANQGGGVVGSTLMLTDLADVHQFFQFPSLRTPTSVSWCFLNYTKPNYAHTTPLSSVYGSWCISSYNPNPLNLSTKATLALLRSKQRKNTEMYTMAAMHQPGTGKLVSSLRWKQKFEQLKPEHIQLDVGKFAKKMKGISSRDRGKEDHGEKEACSKQAEPTRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKFCNFAFKTKGNLTKHMKSKAHMKKCLELGVSVTSVDETEAEELDTTEEVQRGSEKKGMSEIMAEHQFSDADDSEGAEEDGDEVDDDEDDDDDYEGDSTPKTRSRSTSPQPCSIPSLAITAIAASQESIPEGLAISKQPIFTYFTSLPSIQITQLMAPSEKAGEIQMAEYQKLLQGALGEDHKNRLDVPSSMDEDLALSPEHSSSSFEFSCSRLSSPGCDSSPLRESSPSSRRYLSPRRDLSPRGRLSPRREASPLRHISPRRDVYRRDLSPRRDLSPRGHLSPISQTGRPTSPGRDLSGRLSPRSRRGMIRPVSPRRGLHYQSGPWALSPSPHAEMISLSQKTKGHAEPEMDQRKTSHLQGDPRNTDAPSINQGLFSHLPLHSQQQIRTPFSMIPIGGIQMVHSVPTSVTGHAHSTRLPLQKSTSEESSTSEVSFHLSEGRGPASKGSEDSPQSQEKSTSPKAPSLSPQKSREDSTEMSDKESKQEECIQTCTKAIASLCIASEETTDRQPLPIDPYHQRTLSQSPAAQQDCAARAQHYCSSEISHPLHSRAESSVSATSKTPTASHPTLYNTETAERVSGQQSRGERPATIKKSKDSKDNR", "length": 2323 }, "evidence": [ { "id": "RGD:61988", "url": "https://alliancegenome.org/gene/RGD:61988#orthology", "database": "AGR" }, { "id": "HGNC:4921", "url": "https://alliancegenome.org/gene/HGNC:4921#orthology", "database": "AGR" }, { "id": "MGI:1338076", "url": "https://alliancegenome.org/gene/MGI:1338076#orthology", "database": "AGR" }, { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PBC6-1", "protein_name": "Zinc finger protein 40", "gene_name": "hivep1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNRQREIEETLSINTDKIEEAQKEFKDPKGAHKDTNESTGRNSESIKGLKRKKVVAQNQLKKIPKSPVKKQSQTKKSISSNISSKEATPSSFPSSPSHGSPKPEDAEDGPEEVSASRTVKVEQEEISTSEPQALSHKGAAAEPCVAEPVQTESWCGDSCNKSTQSPSHTSAPLEVLLKAMEPDFIDFTERKNSSPIGHLGKSASNPVTYSDYAVAMPAVNFNIQSQNSFMQPFNAAKQYYSSVASTGQHITQPYMSGNRQQEKPGVQKSYSVGPSLTLMHAPVPSGSGGFPQSQPPVVQTCQSLSATVPNSIQVPVTPGYNPVQMTTVVNFGASQVSDISAKDQKPKKQGKYVCEYCKRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHAIKLGLVKDSGSGSLSQESDKGLATHSDVDESGDSDEESSAADLDADSSQSSLTALSESSLQSASMIQGSQAESEHSLVFENLKPSATQRGCEPKVTAALPKVVVHPVNVSPLRADSPRVTDSAPEQATAQRQRDFQPTNLRSNVTVLSSLKEVDCTSPPQDSVSDDEDQHCKSPLGGSHAQLQRQQATDYSQQAQVKCLLSPRSLGSTDSGYFSRSESADQAMSPPSPFVKITPPGDTDITKTPHIPPCPVVAAVMHVATIEKPRVPSGQMRPPLETKALSLEERISKLISDNEAVVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPPVRRSSSNSDIPKSPFTPTDKSKQVFLLSVPSQYPAMECLPITRSNSMPTTPGQSALFPNVTTQPHQLRICQSFDDKISSLNDDVFSSAPSTPNPAVHPRTLVRQIAVEDLSTNDGHVLIQVHSMDESHHGPSITHELRSKSFEHATERNRKPQQNKGTMYECETCRNRYRKLENFENHKKFYCSELHGPKNKPMHARETEHEVFGRGIQQPLLNRNAVITGNVEQPLMLRKRRKIKSVGDDDDQSPTETTPPCSRSFDSSQSSTGSIGRTNSHHTQSLGNSAILGQIQIIARAGELQESRLSPIREAQISTPCKERGDLQRQGSGTSVIRHTNSLSRPNSFETSESIDRSSPVDPVEKETKISVKSHTETAVSSSQSYHDRMSTPKCPSQTHEKQSFAIVGDVPPVQQSRLVRQSNIQVPEILVTEEPDRDHETQVVESTEKPAETFSWPQRSESLSKLPTEKLPPKKKRIRLAQMEHSSGESSFESSLSRSLSRDSSLSRCSSISASFDRDDPPRSDSPSRADSVGKPPETQGVPVANNTLGVPGIMRRSTSEQISYTQSSVEISCDYRSKSFDCSSMSPSRPLSPMQTALPKTTQCPPSTLVPLIERRRGPLVRQMSLKIAPEPQIAVKQTTPIQRVPFTNECSGSQPRSVNLNTSALAQCFAVHSGEVSLPKNEQVVQSINLGGKTEQPQVHGLPHPWHQTSRVVAGHVQPLVHMVGGQTDIKKSSDEKNKIFIPKYQMNCPVLKTGQTYSLAGVQGTQIPLPVITIPIANEIKGSHSNDGMQNVYVAQSSYQAVLNKPSIVQPSNAQVDTASHKVPVSAPVPQILITHEHTLASASAVSKVSFPIAPSVNRDSKIGPEIQAQKQPGSVAVQMKNNMKTTDQIQNTEQSILSLGSLHCMQKLASANLCPQESTASSKRMLSPANSLDIAMEKTQKRAKDEHGAACLTDGRSLNYLNSKMSEITRQRKLMLVRQVCTTEPVDSPIETDAPEQLPETLDTEKNTQKPIPQVTTTEVSEQEMESRTPTTTPPARSLPGVQGYPMLENSTLKPQEKPEEQRWSPSKSPLRPPSFQGQVKLASSVSVVNTRDSHRLSFPSLKTATTFTWCFLMKRKPLHVQQMDQRISAYSAWVVNPNNPNPLGLPTKVVMSLFDSKQTSKKIHYTQAKTTTLKSDILTYSGKLKDVLPKVLIQQRSVPSENSGKTKPDTQPVNQKESDRDTSKSEPQRVKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLRKHIRTHSDIRPFHCTHCNFSFKTKGNLTKHMKSKAHSKKCMEMGVAVGIIEDQDAEDSGDRGRAGSADRQDSDGDDSDGPDDEDNEGEEEDEEDSQAESGLSATPSVSASPQHFSANQADLAPSSLLAQMSISPNPSPALQSQPPPTSDSQTSDTESVAMTSPVSLVRQMSISASCSSPGPNPTSFTSHPTPASESHTSDTDSVHMMSPVSPCRQMSIDYPDFDVPPSPPVSGKGAKLGQDGVSSTISQPASECNANVDRGTQTSSDPLQGSLHFPHAGPLHEPRIGATTHLFSHLPLHSQQPPRSPYSMVPVGGIQLVPAGLAAYSTFVPIQAGPVQLTIPALSVIHRQTGSPLSAPNTSPRPDCSPTQPLVVQEPVSSVLPCFPLGQVAGLQTLGAHQTALQPVGLETLSVVGLANSTQLVPQQSLPLNATLGVQVLAASPAPQCSTASPAQIPGLQILNIALPALIPSLSPLSALSPLPATQDKPRSPEGVASVTLPAQVAGSPPAPLPSASPPTANPGDAAVNAKPCMEVRKVSQNNPSVGSRDTGGAEKTTGMVEKSKAPPQPPSPCSPSLSNERGCNVAHKGSAGEACEVKPRQPVSRQPVTDDYNEASSDDEDRLVIAT", "length": 2636 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z8F4-1", "protein_name": "Protein schnurri", "gene_name": "shn", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARRKGSGRGKSTVNSRKSALETAREKTKDEPTANTSQDNKFDNNMENATTTTAKHYKTAGKQYKTNKVNNTRRATAAAAAAAAAAATTTVTTAATPTKKRTYRETATATIVTQRSTNKANIAAAIALAAATEATASASASATATATDATLTASKAAATAAATTDAASGNSNSSSKPSTSTRDKLGEVPLPTVDSNHIISNNNNNNNNNNTSNNNNNNHHSDNSISENNYEFKSRDKASLSDSKMTLQQMAAVSSNQEPVAPNVANTMSNSSIINSQQTTVNATPATDEAPLGDRSNISRYLHKKFKRLASTTEVDSWSATNGGGALQASGDAVRTTSLSSNSSLSPPPTTPLANGHHLMTQQQSHQQVQQQQQQQQTPPPSVAIHEFSANFVNSNHVNAIGHEESIISNSGYKAAGRTRTPLANSNSNTNSTSNSNSNHAANATLSPASFAQHQQLTQPTTVSPGIPGGAAAPNPACEKSGRYVCQYCNLICAKPSVLEKHIRAHTNERPYPCDTCGIAFKTKSNLYKHCRSRSHAARARGLEVPADADDGLSDQDAELSNSSSELPSRAGSPYEEPINSPTPSPSTLSAAKSAYIQQPPLPTYMQQLPLGSPAAGTLPPTTADNHHSATAQHRQSIDYKPYKPKFHNASLYSCSSKELQQQQQQLQIQQQQQQHQLAQQKLSIQLPLVQQPSLAHPTLSPSTQMKMKHHINSHQIQLQLQQQQSLLAQQSLLAAMPPGGVYYLGQPSYYNQDTAAAIHQHALAIQQFQIHLAQQQQQQQQQHPPLVKATPPMQQPPSLPPQQLVRANSQISSVATAPATPTPAANLSTFASSSGGKQVNVAKVQEHISKLISQNEAIVENKEILLQKKYPKQLSRSRSFNNANSNNASQHGSNASALHANNSQNNTNAQMPERETKVNLAQAIFQKQQHQLQQQQQQQITQQQQQQLEQQNYYTYIQQQQECQQQQLEPPNGVVKRNAYKPGVVMTTPVKQQQQLPPPPSPLPMQTMQYRQDPATPVTKIEQPTTAVPVMPLNLSAKPKPTLVTVPVSSLSTSSLAPTPTTSTNPTSSSKTAPPPAQVNNSIIKNLLLNARGLAVPIGEGDDAVYSCPICASEFRSADDLKLHNSTYCQDASSSAPMSPASSPFRSNSISLSLPELKSHMANSKNPLSLAKLAWSQLKTKRSSLVLSRLSAAQTPARTSTVTAPTVTASAPAPAVATVTAPSSAPAPQIEALRFVDAPLPSPGPLLGKTPLVDYAQQSTPRKAQDSVVITKMHEDRQFVIEAQPAKRIKTSDLVVASSSQQPTSFNFSFNNQNSSNSVPELQSSKEERLRRFTSSGGSMIPISECPDLDNSPKMIRTPLLSGGSFQDVSVKVNNETGSSSKERKLMALVSGSGLLGVSSGPQHFQFPPINSITAFNPLTLPPMSGGDKTTPVTPIPHVPGMPGPGSLTPQMPLLPPPPQQLQLPIPSSRGRSPNRKQPSPLLLGGGSGELKALSPFGGVQNVPSEFSRQPPTPAQRQALQWNSKEAPKKAPFNFLRMADNVKTTEPEVRHFNLENVISGKQQELPLTPLHVDTPNGNAPEETSPVASASASAKSKFLRPTSLPLKPGTFTPKRHHGITPTANTLPLISPETPRPSKSCVQLYLNGHAYTYLGLKCSTKMFYCTVNCPQPSYVAGMHKLSMYSVWQVCEENQPHPLGFKLKQVMALYDSRQRMLGNGSSTAMAGSGKLSYNLVASQQIVSSPSTSSTSSAFYQGPLKTPPTVTIAALSEANVAAKANEEAQAKKLETSPSGQPLVGGYESHEDYTYIRGRGRGRYVCSECGIRCKKPSMLKKHIRTHTDVRPFTCSHCNFSFKTKGNLTKHMQSKTHFKKCIELGINPGPMPPDSEFLDVDMDFDQQSSTSAGGRTSSMAGESDSDDYSDNESESSDTDESKSRQKEHEAARGLLSLSMTPPIPQSVSPYPQLQDTPLPAASPANSIGSSGSQPKRLVCSFTSPKPPFDYQKQEQYYSNPEESKPKRSVANEESAPMDLTKPRGSILLISPSPVSVPAHDLPKSQAQQMHDVIFGTSGNESGFMKTLISVSDKVRISAEMEEQAKHEAEGEDVQLQTYIKEHALHQAKIKQSQFSRSYLINTLYTAASPVMSSSSTLFTANSRPVMSVNEVPSIEVHEVKTPEAIESPRSAPEQAPVILAQIAQEENEEPNIAEPHNANLPAAVQQPDVNEFTGVLGNPTAPPTSSVTATSVSTTTAAPVAPSSTANSTQPAQRTVIVGEDGFKSSTPTSKSGDLQHVSYGRGVPPAPIAGDARPTCTMCSKTFQRQHQLTLHMNIHYMERKFKCEPCSISFRTQGHLQKHERSEAHKNKVMMTSTFGVPTTSNPRPFECTDCKIAFRIHGHLAKHLRSKTHVQKLECLQKLPFGTYAEIERAGISLTEIDTSDCENSLISLKLLAQKLQEKDPGKLSSYTTPSGMMQLAQDAAGPVSQDSASEDGFSAAIASAIASLDNDSAGNTPKRASSMSEDETVANGLNHSLKRRLPGSFSSTGEESDNPPESSGEKRARSGQELPVPVAVPVAASAAASN", "length": 2577 }, "evidence": [ { "id": "RGD:61988", "url": "https://alliancegenome.org/gene/RGD:61988#orthology", "database": "AGR" }, { "id": "HGNC:4921", "url": "https://alliancegenome.org/gene/HGNC:4921#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-562", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-562#orthology", "database": "AGR" }, { "id": "MGI:1338076", "url": "https://alliancegenome.org/gene/MGI:1338076#orthology", "database": "AGR" }, { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A2A884-1", "protein_name": "Transcription factor HIVEP3", "gene_name": "Hivep3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPDQSIKGTKKADGSPRKRLTKGEAIQTSVSSSAPYPGSGTTAPSESATQELLATQPFSGPSQEKTGQQQKPARRPSIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASILPPEELPGIPKVFVPRPSQVSLKPAEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGSSSEMYPPGLEMERIPGEEFEEPTEGESTDSEEETGAASGPSTDVLPKPKHPLLSSSLYSSGSHGSSQERCSLSQSSTGPSLEDPAPFAEASSEHPLSHKPEDTHTIKQKLALRLSERKKLIEEQTFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTSMLASTSTQPLLPLSSEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLTRRSSVESPKSSLYRDSLSSHGEKTKQEQSLLSLQHPPSSTHPVPLLRSHSMPSAACTISTHHHTFRGSYSFDDHVADPEVPSRNTPVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDPTSKPSDEPEPKESDLTKKTKKGFKTKGANYECTICGARYKKRDNYEAHKKYYCSELQITKAHSVGAHEVEKTQAEPEPWSQMMHYKLGATLELTPLRKRRKEKSLGDEEEPPAFGSPGPSETAHNRPLGSTKSPAEASKSAPSLEGPTSFQPRTPKPGAGSEPGKERRTMSKEISVIQHTSSFEKSDPPEQPSGLEEDKPPAQFSSPPPAPHGRSAHSLQPRLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESSISLSGSSRSASFDREDHGKAEAPGPFSDTRSKTLGSHMLTVPSHHPHAREMRRSASEQSPNVPHSSHMTETRSKSFDYGSLSPTGPSLAVPAAPPPPAAPPERRKCFLVRQASLNRPPEAELEAVPKGKQESSEEPAASKPSTKSSVPQISVGTTQGGPSGGKSQMQDRPPLGSSPPYTEALQVFQPLGTQLPPPASLFSLQQLLPQEQEQSSEFFPTQAMAGLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPSQLHLPQLLPHAADIPFQQPPSFLPMPCPAPSTLSGYFLPLQSQFALQLPGEIESHLPPVKTSLPPLATGPPGPSSSTEYSSDIQLPPVTPQATSPAPTSAPPLALPACPDAMVSLVVPVRIQTHMPSYGSAMYTTLSQILVTQSPGSPASTALTKYEEPSSKSMTVCEADVYEAEPGPSSISKEQNRGYQTPYLRVPERKGTSLSSEGILSLEGCSSTASGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVSTCSVVLTSTEDRKKTEKPHVGGQGRSRREAETLSSLSSDVSDPKELSPLSHSTLSHGTAPGSEALKEYAQPSSKAHRRGLPPMSVKKEDPKEQTDLPPLAPPSSLPLSDTSPKPAKLQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSNSRKPRMTEVHLPSLVSPESQKDPARVEKEEKQGKAEEGTPTSKRGEPARVKIFEGGYKSNEEYIYVRGRGRGRYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLHQDSEGQEGAEAVEEHQFSDLEDSDSDSDLDEDEEEEEEEEESQDELSGPCSEAAPPCLPPTLQENSSPVEGPQAPDSTSDEVPQGSSISEATHLTASSCSTPSRGTQGLPRLGLAPLEKDMSSAPSPKATSPRRPWSPSKEAGSRPSLTRKHSLTKNDSSPQQCSPAREAQASVTSTPGPQMGPGRDLGPHLCGSPRLELSCLTPYPIGREAPAGLERATDTGTPRYSPTRRWSLGQAESPPQTVLPGKWALAGPCSPSADKSGLGLGPVPRALLQPVPLPHTLLSRSPETCTSAWRKTESRSPSAGPAPLFPRPFSAPHDFHGHLPSRSEENLFSHLPLHSQLLSRAPCPLIPIGGIQMVQARPGAQPTVLPGPCAAWVSGFSGGGSDLTGAREAQERSRWSPTESPSASVSPVAKVSKFTLSSELEEERTGRGPGRPPDWEPHRAEAPPGPMGTHSPCSPQLPQGHQVAPSWRGLLGSPHTLANLKASSFPPLDRSSSMDCLAETSTYSPPRSRNLSGEPRTRQGSPELLGRGELRTPLFLPKGSGPPSI", "length": 2348 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZRB5-1", "protein_name": "Transcription factor HIVEP3", "gene_name": "Hivep3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPDQSIKGTKKADGSPRKRLTKGEAIQTSVSSSTPYPGSSTTASSEGASQELLAPQPFSGPSVALREGAQEKTGQQQKPPRRPSIEASAHIPKLPQHPLTPAFMSPSKPEHLLEGSTWQLVDPTRPGPSGSFVAPGLHPQSQLLPSHASILPPEDLPGIPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGSSSEMYPPGLEMERIPGEEFEEPTEGESTDSEEETGATSGPSTDVLPKSKHPLLSSSLYSSGSHGSSQERCSQSSTAPSLEDPTPFAEASSEHPLSHKLEDTHTIKQKLALRLSERKKLIEEQTFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTSMLASTSTQPLLPLSAEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLTRRSSVESPKSSLYRESLSSHGEKTKQEQSLLSLQHPPSSTHPVPLLRSHSMPSAACTISTHHHTFRGSYSFDDHIADPEVPSRSTPVFTSHPRMLKRQPAIELPLGAEYSSEEPGPSSKDPITKPSDEPEPKESDLTKKTKKGLKTKGVNYECTICGARYKKRDNYEAHKKYYCSELQITKAHPAGAHEVEKTQAEPEPWSQMMHYKLGATLELTPLRKRRKEKSLGDEEEPPGFSSPGPSDAAHNLPLESTKSPAEASKSVPTLEGPTSFQPRTPKPGSGSEPGKERRTMSKEISVIQHTSSFEKSDPPEQPGSLEEDKPLAPFSSPPPAPHGRSAHSLQPRLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESSISLSGSSRSASFDREDHGKAETPGPLSDTRSKTLGTHMLTVPSHHPHAREMRRSASEQSPNVPHSSHMTETRSKSFDYGSLSPTGPSVAVPAAPPPPAAPPERRKCFLVRQASLSRPPEAELEATPKGKQESSEEPSASKPSTKSSMAQISVATIQGGLSGSKSQMQDRPPLGSSPPYTEALQVFQPLGTQLPPPVSLFSLQQLLPQEQEQSSEFFPTQAMAGLLSSPYSVPPLPPSLFQAPPLPLQPTVLHPSQLHLPQLLPHAADIPFQQPPSFLPMPCPAPSTLSGYFLPLQSQFALQLPGEIESHLPSIKTSLPPLATGPPGPSSSTEYSSDIQLPPVTPQATSPAPTSASPLALPACPDAMVSLVVPVRIQTHMPSYGSAMYTTLSQILVTQSPGSSTSMALTKYEEPSSKSMTVCGADVYEAEPGPSSISKEQSRGFQTPYLRVPERKGTALSSEGILSLEGCSSTASGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVSTCNVVLTSTEDRKKTEKPHVGSQGRSRRETETLSCLSSDVSDPKELSPLSQSTLSHGTAPGSEALKEYAQPSSKAHRRCLPPLSVKKEDPKEQTDLPPLAPPSSLPLSDTSPRPAKLQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSNSRKPRMTEVHLPSMVSLESQKDPARVEKEEKAEEGTPTSKRGEPTRVKIFEGGYKSNEEYIYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCRHCHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLLQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEEEEEEEEEESQDELSRPSSEAAPLCLPATLQEDSSLIRGPQPPDATSDAAPRGSSISEATRLTASSCSTPSQGTQGLPRLGLAPLEKGTSSALSPKATSPRRPWSPSKEAGSRPSLTRKHSLTKTDSSPQRCSPARAQASVASTPGPQTGPGRDLSPHLCGSPRPELSCLTPYPIGREVPAGLESATVTGTPRCSPTRRRSLGRAESSPPHTVLPGTWALGGPCSPSVDKYGLGLGPVPRALLQPVPLPHTLLSRSPETCASAWTESRSPSAGPAPLSSRPSSAPHDFHGHLPSRSEENLFSHLPLHSQHLNRTPCPLIPIGGIQMVQARPGAHPTLLSGPCAAWVSGFSGGGSDLTGAREAQERSRWSPTESPSASVSPVAKVSKFTLSSELEEERTSRGPGRPPAWEPHRAEAPAETMGTHSPCPPQLPQGHPLAPSWRGLLESPHALANLKASSFPPLDRSSSMDCLAETSTCFPPRSRNLSGEPRTRPDSPELLGSGELRTPLFLSKDSGPPSI", "length": 2349 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9H4-1", "protein_name": "Zinc finger protein 40", "gene_name": "Hivep1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRTKQIHPRNLRDKIEEAQKELNGAEVSKKEILEAGVKGASESLKGVKRKKIVAENHLKKIPKSPLRNPLQTKHKQNTEEPLFSALQSAPESHKKHNCVPVKQGRQFTKQNGETPGMTVEASESGDSVSPKKASSPHHRSELRRWRSEGSDPARLSGLDGQRDSSSSSSKTRTDNSECSSPCCSTTPPSYTSTAFDVLLKAMEPELSTLSQKGSSCAVKTEKPRPNRTVRSPSKLKNSSLDAPNPASPELVAESQCSPCTSYPVPVASTQKSEQVAAQRVSHLHSQYDHLVPKPGQQNPQLPGHLGLAGSLTNPHTHENTKLEPIYNIAMTSTVGLASPSSRTQVTPPHQQMDSVSPSSVSPATSTQSPPGPIYSSTHVASVVSQSVEQMCNLLLRDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHTIKLGLVLQPEAGGLFLSQECPKALSVHSDIEDSGESDEEGPGDGRQNDPSVRDLQPVQIMKMPSDPEALPKSIASRADHVVSGFSSQDRPSESQALTELPKVVVHPVSMSPLKTDSVQVASPKPELPSTQSQKDLHAASRLSHSAGVSSLETDETCHQKGDVTLSEGKPEPHSGAAHAQLQRQQATDDPQEQQGKLLLSPRSLGSTDSGYFSRSESADQAMSPPTPFARTFPTTDPDPAKNSGPAGPRISAPAPAALAPGEKSSVVAGQMRPPLATKTLEERISKLISDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPMGRRTSSSSDIPKSPFTPTEKSKQVFLLSVPSLDCLPITRSNSMPTTGYSAVPANIIPPPPPLRGSQSFDDKIGTFYDDVFVSGPNPSMPPSGHHRPLVRQAAVEDSTASENHVLGSGQSVDESCQGCPASSEPGPVQSKAANTPHLEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTKVAAREPEHGLAPGGVQPQVLHYRVAAPTAVWEQTPQIRKRRKMKSVGDDEDLQPRESGRSPESAEALQLQPVPGSAPSPSKQAPATAGDQAHRGVQLQSSPVQLVARVPEQALPLKQCPVVEQQLNSATQDRIEVQRQAGGISVIQHTNSLSRPSSFDKLEPLEGGTAFSLQELGRAGMPGALKVIGMPPEEGHPPRDATHQIALSRESARKIPSERFVLGQPLRLVRQHNIQVPEILVTEEPDRDLEAQSHDEEKSEKFTWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFESTLSRSLSRESSLSHASSFSASLDVEDISKVELSPKTDFPSKAEFLFIPLGSNTLSVPGSHREMRRAASEQISCVPTLMEVSDFRSKSFDCGSIAPSHVVPALVEPQPSNSPSGVGGTGHVPLLERRRGPLTRQISLNIASDSPLSPGSVSALQTIVLPGVNAIPLQALRPPDVASADLPAHTVPSQALAKDLQAEMSSCSSTDTFPPQQLFGAHLLNKTNMPLSHQNTPLPLPVSVQGGKPGAPPPAGTSSTGDGSFAPKYQLQCQAFTSGRGCSSSPLHSLPNPVLPDQTAADPCTASVALSAKAVDPVSKSYPLPSLELGLPSDQVQKRLPSFVLPVLQPRDVPVYCLSTVTSLPQILVTHDLSNTPICQTNQSIVPVSEEQNPMPKSQNYLQNALPTPEKDLACKTVLSEMGQNAPVSESSATVQKVSAGRLSPQQESSASSKRMLSPANSLDIAMEKHQKRAKDENGAVCSTNIRPLELPSSRANEGHKQKKPVLVRQLCTVEPLEGTALEQDPGSASGKSSRNADSTQVLSTDSLSSRHSMFAVPDHVSEFQEFKNTKLSTSLTPTVGSSHIPLESACVLPLKSRDDNQEKGSSGVQNEENKVIQGQRQPPIPGLSVLSSSDTQQPSFPSLKTATSFTWCYLLRQKSLPLAQSDQKTSAYAGWTVSPSNPNPLGLPTKVALSLLNSKQKTGKSLYCQAITTHSKSDLVVYSSKWKNNLSKRALGNQKATIVEFSNKDDSEINSEQDKENSLIKSEPRRIKIFDGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKSKAHSKKCVDLGISVGLIDEQDTEESDEKQRFGCERSGFDLEESDGPDEDDNDNEEDDDDSQAESGLSAAPSVTASPQHLPSRSGLQDPGSVEEDLRVSSCFSGVHTDPMDILPRALLTKMTVLSTVQIDPNRTDLTAKARQNTGKDELELAPPVDTPISPEVTPRSPGHQMSVHYSESDALRSPAAGNTVASIQDSPSVGLPPATIAQLNPQPAARISSSVSPHPESQEPKQQITLQPSPGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVPAGLTYSTFVPIQAGPMQLTIPAVSVIHRTVGTPVDTITEVSGATNRPTGVAELSSVVPCIPIGQIHVPGLQNLSPPALQSLSSLGMETVNIVGLANATVGPQVHPPGLALNAVGLQVLANAPAQSSPATQTHIPGLQILNIALPTLIPSVGPVAVGTAGTPETATSNSKTVEPQTPAGQGHSAEPPQRLPEGPQETPQTVPGPSVDHARPDGSSKMDTKKVASASHVLPGRSSAQAQPAPIPEALQKIVASGPTSLPTDRPAPRPPVPHRQPIVHFSDVSSDDDEDRLVIAT", "length": 2691 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q7V2-1", "protein_name": "Transcription factor HIVEP3 isoform X1", "gene_name": "hivep3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEALHSQATTGEQSGGLAKQNETPVDNPKPQYHEEKKVVTQVHHAQQRKHLNIERKRLRLQRKSLQERDVVEEGKPPRASGSSEHLNANMSQAREMPSGASSSAVSAKPSCSMEEVLEGTPRQKRERKPQKPGKYVCSYCGRACAKPSVLQKHIRSHTGERPYPCAPCGFSFKTKSNLYKHRKSHTHRVKAGLTADREGPGISCSEEPLTDSDEESQPSSYLEKQRMSVQNSSATERCSEGQLQEIEDSHAVKKRLAMRLSRGRRTPLGSSDEASSSFGQSSKGSTESGYFSRSESTEVSQDSPPNTSAKSYAEVILGKFGRLGHLQRTSHQQHAHPAGQEGKRIPFNVPKKQVIDHITKLITINEAVVDTSKIDSVKPRRFSLSRRSSTELKVVSSKEPFLHSPKEIDISAKSSGSITLGVPCEKFQHHSLSIPQTESTSTAPLLRSHSMPSDASTSDVSETSRSLRLSQSFDDPQPIQNRRHGMLRRQPAIELPIGAELTMEEQSYSTSSFHHPVTTMPDPSQKQEQFECGACRIVCNDVERYQKHKQHCCTVHISQQSEIPVYQVDESTRTFTSRSGAFAFRKRRKEESIEFEDPSLPSVSYIPLRGYAPSCEQPIKRTHELGQEYCTEGSLKGISVIQHTSSFEKHDNSKTDEPSHTHGVSHTSPHPQTKQQATKLSFRKLVRQQNVQVPEILVTEDSNTEAMAVSPPPIVPKMKDTEKVSEFQWPQRSPTLAQLPIEKLPPKKKRLRLAEAAQSSGDSSFESMSLPHSPSQDSCTSHNSSRSTSFEEAGKADADLTPTRRSRATHTLTVPINSHREMRRSASEQAPHIPQTANLITEIRSKSFDYSSLSPDRTPAGWKERRKCLLLRHSAVREPEEEDQTTKVFNTSSPTCRTSTSPSHSPVTSYSPSTHHVSSSNTVHSFGEKQIMKSQDVLSENTQLSTLQLTPVIHTDHPTTVGSLICPSGAARAHYSSMSTGLKLEIPMEKDQPYITHCHQHQNIGFDVTSNPEVLRPLPAQSIPVRLNSHLPYHAGSIYTTVSQTFFSRPQEPCCSGVSSVAVVSKYEIMDQQPDSERSDSVSVGATKRVLSPTSSNELNPESEQQQKRVKEEEENQENERRDDKVLIEFKKEEILGEQSVIFPTEHKDPPFQTLNTNLTFSWCFLNYIKPNPSIQSEQQNSVYSSWCTSTRNPNPPGLTSKEMLSLLQCRQRHETLLYTMASMSPSLDVKQETPDSQKPNVTEVHAAQLTEPKEAQQAELTEVETKTTEEKEDQLSTSKCSSRVQICEGGYRSSEEYVYVRGRGRGRYVCEECGIRCKKPSMLRKHIRLHTDARPYVCQHCNFAFKTKGNLTKHMKSKAHGKRCPEGPAPGPVQCELETDEGGDSAKHFLETEEVEEHQFSDAEESDDEAEDNDEGDEQTSCSSSSSKWTSISRDDSGSCDILGLSNPGWEQHPKPPVSMSPRKPSHYGEASSPKTTKSIVTLLHLDPTTGMCSSPIRSLSPGLQMSPALPQSPGRDMSPLRCPSPRLSLSPSSCLSSLSPSDRSTSSFSERRVSPIRDLSPIRPSSPSCPLALTVGASVTIQYQADRPRASTKASPNRLNLKKKTEKTHSPHRRTNMTQSWPPAHGRLSRNMQPREGQRVLSHLPLHSQPQVMIPNLSLTIPIGGIQMVQPRSNMLLRSTSLNHSVAQMTVTVLTKEKGAGRSPVGEVPHRKNQLIVFTEPAVEMSSKSEASSDEDKEQIHGVVQAELFSRKKEVPSVAMTTWKSISQKNNRKHSRSPKKTQPVDGSRTSMDAKC", "length": 1797 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P15822-1", "protein_name": "Zinc finger protein 40", "gene_name": "HIVEP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRTKQIHPRNLRDKIEEAQKELNGAEVSKKEILQAGVKGTSESLKGVKRKKIVAENHLKKIPKSPLRNPLQAKHKQNTEESSFAVLHSASESHKKQNYIPVKNGKQFTKQNGETPGIIAEASKSEESVSPKKPLFLQQPSELRRWRSEGADPAKFSDLDEQCDSSSLSSKTRTDNSECISSHCGTTSPSYTNTAFDVLLKAMEPELSTLSQKGSPCAIKTEKLRPNKTARSPPKLKNSSMDAPNQTSQELVAESQSSCTSYTVHMSAAQKNEQGAMQSASHLYHQHEHFVPKSNQHNQQLPGCSGFTGSLTNLQNQENAKLEQVYNIAVTSSVGLTSPSSRSQVTPQNQQMDSASPLSISPANSTQSPPMPIYNSTHVASVVNQSVEQMCNLLLKDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHTIKLGLVLQPDAGGLFLSHESPKALSIHSDVEDSGESEEEGATDERQHDLGAMELQPVHIIKRMSNAETLLKSSFTPSSPENVIGDFLLQDRSAESQAVTELPKVVVHHVTVSPLRTDSPKAMDPKPELSSAQKQKDLQVTNVQPLSANMSQGGVSRLETNENSHQKGDMNPLEGKQDSHVGTVHAQLQRQQATDYSQEQQGKLLSPRSLGSTDSGYFSRSESADQTVSPPTPFARRLPSTEQDSGRSNGPSAALVTTSTPSALPTGEKALLLPGQMRPPLATKTLEERISKLISDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPVGRRTSSSSDIPKSPFTPTEKSKQVFLLSVPSLDCLPITRSNSMPTTGYSAVPANIIPPPHPLRGSQSFDDKIGAFYDDVFVSGPNAPVPQSGHPRTLVRQAAIEDSSANESHVLGTGQSLDESHQGCHAAGEAMSVRSKALAQGPHIEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTKVAMREPEHSPVPGGLQPQILHYRVAGSSGIWEQTPQIRKRRKMKSVGDDEELQQNESGTSPKSSEGLQFQNALGCNPSLPKHNVTIRSDQQHKNIQLQNSHIHLVARGPEQTMDPKLSTIMEQQISSAAQDKIELQRHGTGISVIQHTNSLSRPNSFDKPEPFERASPVSFQELNRTGKSGSLKVIGISQEESHPSRDGSHPHQLALSDALRGELQESSRKSPSERHVLGQPSRLVRQHNIQVPEILVTEEPDRDLEAQCHDQEKSEKFSWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFDSTLSRSLSRESSLSHTSSFSASLDIEDVSKTEASPKIDFLNKAEFLMIPAGLNTLNVPGCHREMRRTASEQINCTQTSMEVSDLRSKSFDCGSITPPQTTPLTELQPPSSPSRVGVTGHVPLLERRRGPLVRQISLNIAPDSHLSPVHPTSFQNTALPSVNAVPYQGPQLTSTSLAEFSANTLHSQTQVKDLQAETSNSSSTNVFPVQQLCDINLLNQIHAPPSHQSTQLSLQVSTQGSKPDKNSVLSGSSKSEDCFAPKYQLHCQVFTSGPSCSSNPVHSLPNQVISDPVGTDHCVTSATLPTKLIDSMSNSHPLLPPELRPLGSQVQKVPSSFMLPIRLQSSVPAYCFATLTSLPQILVTQDLPNQPICQTNHSVVPISEEQNSVPTLQKGHQNALPNPEKEFLCENVFSEMSQNSSLSESLPITQKISVGRLSPQQESSASSKRMLSPANSLDIAMEKHQKRAKDENGAVCATDVRPLEALSSRVNEASKQKKPILVRQVCTTEPLDGVMLEKDVFSQPEISNEAVNLTNVLPADNSSTGCSKFVVIEPISELQEFENIKSSTSLTLTVRSSPAPSENTHISPLKCTDNNQERKSPGVKNQGDKVNIQEQSQQPVTSLSLFNIKDTQQLAFPSLKTTTNFTWCYLLRQKSLHLPQKDQKTSAYTDWTVSASNPNPLGLPTKVALALLNSKQNTGKSLYCQAITTHSKSDLLVYSSKWKSSLSKRALGNQKSTVVEFSNKDASEINSEQDKENSLIKSEPRRIKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKSKAHSKKCVDLGVSVGLIDEQDTEESDEKQRFSYERSGYDLEESDGPDEDDNENEDDDEDSQAESVLSATPSVTASPQHLPSRSSLQDPVSTDEDVRITDCFSGVHTDPMDVLPRALLTRMTVLSTAQSDYNRKTLSPGKARQRAARDENDTIPSVDTSRSPCHQMSVDYPESEEILRSSMAGKAVAITQSPSSVRLPPAAAEHSPQTAAGMPSVASPHPDPQEQKQQITLQPTPGLPSPHTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVPAGLTYSTFVPLQAGPVQLTIPAVSVVHRTLGTHRNTVTEVSGTTNPAGVAELSSVVPCIPIGQIRVPGLQNLSTPGLQSLPSLSMETVNIVGLANTNMAPQVHPPGLALNAVGLQVLTANPSSQSSPAPQAHIPGLQILNIALPTLIPSVSQVAVDAQGAPEMPASQSKACETQPKQTSVASANQVSRTESPQGLPTVQRENAKKVLNPPAPAGDHARLDGLSKMDTEKAASANHVKPKPELTSIQGQPASTSQPLLKAHSEVFTKPSGQQTLSPDRQVPRPTALPRRQPTVHFSDVSSDDDEDRLVIAT", "length": 2718 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P31629-1", "protein_name": "Transcription factor HIVEP2", "gene_name": "HIVEP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTGDTALGQKATSRSGETDKASGRWRQEQSAVIKMSTFGSHEGQRQPQIEPEQIGNTASAQLFGSGKLASPSEVVQQVAEKQYPPHRPSPYSCQHSLSFPQHSLPQGVMHSTKPHQSLEGPPWLFPGPLPSVASEDLFPFPIHGHSGGYPRKKISSLNPAYSQYSQKSIEQAEEAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESAVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKMSPGPPIPLDIASRGGYHGSLEESLGGPMKVPILIIPKSGIPLPNESSQYIGPDMLPNPSLNTKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNALSVTTTSQERAAMGRKGIMEPLPHVNTRLDVKMFEDPVSQLIPSKGDVDPSQTSMLKSTKFNSESRQPQIIPSSIRNEGKLYPANFQGSNPVLLEAPVDSSPLIRSNSVPTSSATNLTIPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHVEVEHHGRMLKGISSSSLKEKKLSPGDRVGYDYDVCRKPYKKWEDSETPKQNYRDISCLSSLKHGGEYFMDPVVPLQGVPSMFGTTCENRKRRKEKSVGDEEDTPMICSSIVSTPVGIMASDYDPKLQMQEGVRSGFAMAGHENLSHGHTERFDPCRPQLQPGSPSLVSEESPSAIDSDKMSDLGGRKPPGNVISVIQHTNSLSRPNSFERSESAELVACTQDKAPSPSETCDSEISEAPVSPEWAPPGDGAESGGKPSPSQQVQQQSYHTQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAQSKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFEREETSKLSALPKQDEFGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPAEVPEVRSKSFDYGNLSHAPVSGAAASTVSPSRERKKCFLVRQASFSGSPEISQGEVGMDQSVKQEQLEHLHAGLRSGWHHGPPAVLPPLQQEDPGKQVAGPCPPLSSGPLHLAQPQIMHMDSQESLRNPLIQPTSYMTSKHLPEQPHLFPHQETIPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQAHFPHPFAQHPQKSYGKPSFQTEIHSSYPLEHVAEHTGKKPAEYAHTKEQTYPCYSGASGLHPKNLLPKFPSDQSSKSTETPSEQVLQEDFASANAGSLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGFNIAQVLGQHAGLEKYPIWKAPQTLPLGLESSIPLCLPSTSDSVATLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKDLSRPQKPQLVRQGCASEPKDGLQSGSSSFSSLSPSSSQDYPSVSPSSREPFLPSKEMLSGSRAPLPGQKSSGPSESKESSDELDIDETASDMSMSPQSSSLPAGDGQLEEEGKGHKRPVGMLVRMASAPSGNVADSTLLLTDMADFQQILQFPSLRTTTTVSWCFLNYTKPNYVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITAEIYTLAAMHRPGTGKLTSSSAWKQFTQMKPDASFLFGSKLERKLVGNILKERGKGDIHGDKDIGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDDTETEEAENLEDLHKAAEKHSMSSISTDHQFSDAEESDGEDGDDNDDDDEDEDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVPHGVPSDSSLGHSSLISYLVTLPSIRVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSCMDEECMLPSEPSSSPRDFSPSSHHSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQRDVSPRRHLSPRRPVSPGKDITARRDLSPRRERRYMTTIRAPSPRRALYHNPPLSMGQYLQAEPIVLGPPNLRRGLPQVPYFSLYGDQEGAYEHPGSSLFPEGPNDYVFSHLPLHSQQQVRAPIPMVPVGGIQMVHSMPPALSSLHPSPTLPLPMEGFEEKKGASGESFSKDPYVLSKQHEKRGPHALQSSGPPSTPSSPRLLMKQSTSEDSLNATEREQEENIQTCTKAIASLRIATEEAALLGPDQPARVQEPHQNPLGSAHVSIRHFSRPEPGQPCTSATHPDLHDGEKDNFGTSQTPLAHSTFYSKSCVDDKQLDFHSSKELSSSTEESKDPSSEKSQLH", "length": 2446 }, "evidence": [ { "id": "RGD:61988", "url": "https://alliancegenome.org/gene/RGD:61988#orthology", "database": "AGR" }, { "id": "HGNC:4921", "url": "https://alliancegenome.org/gene/HGNC:4921#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-562", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-562#orthology", "database": "AGR" }, { "id": "MGI:1338076", "url": "https://alliancegenome.org/gene/MGI:1338076#orthology", "database": "AGR" }, { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q00900-1", "protein_name": "Human immunodeficiency virus type I enhancer-binding protein 2 homolog", "gene_name": "Hivep2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTGDTALGQKATSRSGETDSVSGRWRQEQSAGLKMSTFSSQEGQRQPQIDPDQIGNVASAQLFGSGKLASPGEGVHQVTEKQYPPHRPSPYPCQHSLSFPQHSLPQGMMHSNKPHQSLEGPPWLFSGPLPSVASEDLFPFPMHGHSSGYPRKKISSLNPAYSQYSQKSIEQAEDAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESSVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKVSPGPPIPLDIASRGGYPGSLEESLGGPMKVPILIIPKSGIPLPNEGSQYLGPDMLPNPSLNAKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNTLSVTPTGQERTAMGRRGLVEPLPHVNTRLEVKMFEDPITQLIPSKGEMDPSQVNMLKTTKFNSECRQPQAMAASVRNEGKPYPGSFPGSNPILLEAPVDSSPLIRSNSMPTSSATNLSIPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHMEFEHPARVPKILAGSSLKEKKLVPGDRSGYDYDACRKPYKKWEDPETPKQSYRDISCLSTFKHGGEYFMDPSVPLPGVPTMFGTTCENRKRRKEKSVGDEEDTPMICGGMGSAPGSMMSSEYDSKLQDGGRSGFTMTGHESLPHGYSDRLDLARPQLPSRSPSLGSEDLPSAGDPDKMTDLGKKPPGNVISVIQHTNSLSRPNSFERSESTEMAVSTQDKTPSPSEMGDSEVLEGPVSPEWAPPGDGAESGSRPTPSQQVPQHSYHGQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAPTKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADMEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFDRDETVKLTAPPKQDESGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPTEVPEIRSKSFDYGNLSHAPVAGASPSTLSPSRERKKCFLVRQASFSGSPEIAQGEAGMDPSVKQEQLEQLHAGLRAAWTTVLPPLPGDDPGKQVVGPCGQLSSGPPLHLAQQQIMHMDSQESLRNPLIQPTSYMTGKHLPEQPHLFPHQDAVPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQAHFPHPFTPHPQNSYSKPPFQADIHSSYSLEHVAEHTGKKSADYPHAKEQTYPCYSGASGLHSKNLPPKFPSDPGSKSTEAPPTEQLLREDFASENAGPLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGFNIAQVLGQRTGLEKYPLWKVPQTLPLGLESSIPLCLPSTSDSAASLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKGLSRPQKPQLVRQGCASEPKDGSSQSRSSSFSSLSPSSSQDHPAASGPFPPNREILSGSRAPPRRKFSGPSESRESSDELDIDETSSDMSMSPQSSSLPTGGSQQEDEGKARKLPVSMLVHMASGPGGNVANSTLLFTDVADFQQILQFPSLRTTTTVSWCFLNYTKPNFVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITAEIYTLAAMHRPGTGKLTSSSAWKQFAQMKPDAPFLFGNKLERKLGGNVLKERGKGEIHGDKDLGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDETETEEAENMEDLHKTSEKHSMSGISTDHQFSDAEESDGEDGDDNDEDDEDDDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVAHGVPSDSSLGHSSLISYLVTLPSIQVTQLMTPSDSCEDTQMTEYQRLFQSKSTDSEPDKDRLDIPSSMDEEAMLSSEPSSSPRDFSPSSYRSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQGDASPRRHLSPRRPLSPGKDITTRRDLSPRRERRYMTTIRAPSPRRALYHNPPLPMGQYLQTEPIVLGPPNLRRGLPQVPYFSLYGDQEGAYEHHGSSLFPEGPTDYVFSHLPLHSQQQVRAPIPMVPVGGIQMVHSLPPAISGLHPPPTLPLPTEGSEEKKGAPGEALTQDPYTLSRRHEKQAPHVLQSSGLPSSPSSPRLLMKQSTSEDSLNSTEREQEENIQTCTKAIASLRIATEEAALLGADQPTWVQESPQKPLESAHISIRHFSGPEPGQLCTSAAHPDLHDGEKDTFGTSQTAVAHPTFYSKGSVDEKQVDFQSSKELSLSTEEGNEPSSEKNRLH", "length": 2437 }, "evidence": [ { "id": "RGD:61988", "url": "https://alliancegenome.org/gene/RGD:61988#orthology", "database": "AGR" }, { "id": "HGNC:4921", "url": "https://alliancegenome.org/gene/HGNC:4921#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-562", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-562#orthology", "database": "AGR" }, { "id": "MGI:1338076", "url": "https://alliancegenome.org/gene/MGI:1338076#orthology", "database": "AGR" }, { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q03172-1", "protein_name": "Zinc finger protein 40", "gene_name": "Hivep1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRTKQIHPRNLRDKIEEAQKELNGAEVSKKEVLEAGVKGTSESLKGVKRKKIVAENHLKKIPKSPLRNPLQTKHKQNTEEPPFSVLPSASESHKKHNCVPAKQGRQFTKQNGETPGMTAESSESGDLVSPKKTSSPHQRSELRRWRSEGSDPTRLSGLDGQRDSSSSSSKARTDNSECSSPCCSTTPPSYTSTAFDVLLKAMEPELSTLSQKGSSCAIKTEKLRPNKTVRSPSKLKNSSLDAPNATSPDLVVESPCPPCTSYPVHVASTQKSEQVAAQCVSHLYSSQDHLVPKLSQQNQQLPGHLGFTGSLTNLHTLESTKLEPIYNTAVTSTVGLTSPSTRTQVTPPHQQMDSVSPLSVSPASSTQSPPGPIYSSAHVASVVSQSVEQMCSLLLRDQKPKKQGKYICEYCNRACAKPSVLLKHIRSHTGERPYPCVTCGFSFKTKSNLYKHKKSHAHTIKLGLVLQPEAGGLFLSQECPKALSVHSDIEDSGESDEEGLADGRQNNPCVKDLQPVQTMKTVSNPESLPKLIPSNSDHVVRGFSSQDRPSDSQAPTELPKVVVHPVSMPPLKTDCLQVANPNPELPSPQSPRDLHVASILSHSASVSSLEMDESCHQKGDVIQSEGKPDSHSGTAHAQLQRQQATEDPQEQQGKLLLSPRSLGSTDSGYFSRSESADQAVSPPTPFARTFPTMDPDPAKNGGAPGPRISAPAPSALATGEKSSVVTGQMRPPLATKTLEERISKLISDNEALVDDKQLDSVKPRRTSLSRRGSIDSPKSYIFKDSFQFDLKPMGRRTSSSSDIPKSPFTPTEKSKQVFLLSVPSLDCLPITRSNSMPTTGYSAIPANIIPPPPSLRGSQSFDDKIGTLYDDVFVSGPNPSMPPSGHHRPLVRQAAVEDSTASESHVPGSGQSVDESCQGCPSSSEAGPVQSKAAQTPHLEKKKSHQGRGTMFECETCRNRYRKLENFENHKKFYCSELHGPKTKAAVREAEHGPAPGGAQPQVLHYRVAAPTAVWEQTPQIRKRRKMKSVGDEEDLQPHESGRSPESADALQLQPVPGAAPSPSKHTSATAADQAHRGVQLVARGPERALPLKQCPMVEQQLNAAAQDKMEVKRQGGGISVIQHTNSLSRPNSFDKPEPLEGGITFSLQELGRTGMPGALKVIGMAPEEGHPPQDAMHQTALSHNLRGEPRESARKIPSERYVLGQPLRLVRQHNIQVPEILVTEEPDRDLEAQSHDEEKSEKFTWPQRSETLSKLPTEKLPPKKKRLRLAEIEHSSTESSFESTLSRSLSRESSLSHASSFSASLDLEDISKVELAPKIDFPSKAEFLLIPLGSNTLSVPGSHREMRRAASEQISCVPTLMEVSDFRSKSFDCGSIAPSHVVPALVESQPSYSPSAVGGTAHVPLLERRRGPLIRQISLNIASDSHLSPGSAAALQTIVLPSVNTVPFQAPRLPDMASADCPAHTVHPQALAKDLQAEISSSSSTDTFPPQQLFGAHLLNKTNTSLSHQNTPLPLPVSAQGGKPDAAPTACVSSTGEGSFAPKYQLQCQAFTSDQGCSAPLRSSPNQVLPGQAGADPCPASEAPPAKAADPMAKPCPLPPLELGLPRDEVLQKQLPSFVLPVPQKRNVTVDCFTPVTSLPQILVTQDLPNMPICQTNQSLVPVSEEQNSMPKSQNYLQNASPTPEKELACKTVLPEVGQSVPVSESSPTVQKVSVGRLSPQQESSASSKRMLSPANSLDIAMEKHQKRAKDENGAVCSTNIRALELPSSRANESHKQKKPVLVRQLCTTEPLEGAALEQGACSASGRSSNKAANLTQVLPTDSLSSRPSTFAVTDHVNELQEFKNTKVSTSLTPTVGSFPAPSESACVLPLKSIDNNQEKGSPGVRHEENKVIQGQRPPLVSGLSLVSSSDTQQPSFPSLKTATSFTWCYLLRQKALPLAQNDQKTSAYTGWTVSSSNPNPLGLPTKVALSLLNSKQKTGKSLYCQAITTHSKSDLVVYSSKWKNNLSKRALGNQKATVVEFSNKDDSEINSEQDKENSLIKSEPRRIKIFDGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCSYCNFSFKTKGNLTKHMKSKAHSKKCVDLGVSVGLIDEQDTEESDEKQRFGCERSGYDLEESDGPDEDDNDNEEDDDDSQAESGLSAAPSVTASPQHLPSRSGLQDPGSVEEELRVSSCFSGVHTDPMDILPRALLTKMTVLSTVQSSPNRTDLPAKARQSTEKDEHEQAPPADTPRSPGHQLSVHSSESDVLRSPAAGNPAAGSPGAAVQDSSVGLPPAVAQLNPQPAARISSSVSPHPDSQDQKQQIILQPPPGLPSPQTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVTAGLTYSTFVPIQAGPMQLTIPAVSVIHRTVGTSGDTITEASGSPNRPTGVAELSSVVPCIPIGQIHVPGLQNLSPPALQSLTSLGMETVNLVGLANATVGPQGHPPGLALNAVGLQVLANAPAQSSPAPPAHIQGLQILNIALPTLIPSVGPVAVGTTGTPETTAPNSKAMELQMPAGQGHSAEPPQGSPEGPQETPQTVSGPSADHARPEDSTKMDTKKGPSAGHVLPGRSPAQAQPAPTPEALQKVATSAPPSLPTDRAAPRPPVPHRQPIVHFSDVSSDDDEDRLVIAT", "length": 2688 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3UHF7-1", "protein_name": "Transcription factor HIVEP2", "gene_name": "Hivep2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTGDTALGQKATSRSGETDSVSGRWRQEQSAVLKMSTFSSQEGPRQPQIDPEQIGNAASAQLFGSGKLASPGEGLHQVTEKQYPPHRPSPYPCQHSLSFPQHSLSQGMTHSHKPHQSLEGPPWLFPGPLPSVASEDLFPFPMHGHSGGYPRKKISNLNPAYSQYSQKSIEQAEDAHKKEHKPKKPGKYICPYCSRACAKPSVLKKHIRSHTGERPYPCIPCGFSFKTKSNLYKHRKSHAHAIKAGLVPFTESSVSKLDLEAGFIDVEAEIHSDGEQSTDTDEESSLFAEASDKVSPGPPVPLDIASRGGYHGSLEESLGGPMKVPILIIPKSGIPLASEGSQYLSSEMLPNPSLNAKADDSHTVKQKLALRLSEKKGQDSEPSLNLLSPHSKGSTDSGYFSRSESAEQQISPPNTNAKSYEEIIFGKYCRLSPRNTLSVTPTGQERTAMGRRGIMEPLPHLNTRLEVKMFEDPISQLNPSKGEMDPGQINMLKTTKFNSECRQPQAIPSSVRNEGKPYPGNFLGSNPMLLEAPVDSSPLIRSNSMPTSSATNLSVPPSLRGSHSFDERMTGSDDVFYPGTVGIPPQRMLRRQAAFELPSVQEGHMESEHPARVSKGLASPSLKEKKLLPGDRPGYDYDVCRKPYKKWEDSETLKQSYLGSFKQGGEYFMDPSVPVQGVPTMFGTTCENRKRRKEKSVGDEEDVPMICGGMGNAPVGMMSSEYDPKLQDGGRSGFAMTAHESLAHGHSDRLDPARPQLPSRSPSLGSEDLPLAADPDKMTDLGKKPPGNVISVIQHTNSLSRPNSFERSESTEMVACPQDKTPSPAETCDSEVLEAPVSPEWAPPGDGGESGSKPTPSQQVPQHSYHAQPRLVRQHNIQVPEIRVTEEPDKPEKEKEAPTKEPEKPVEEFQWPQRSETLSQLPAEKLPPKKKRLRLADLEHSSGESSFESTGTGLSRSPSQESNLSHSSSFSMSFDREETVKLTAPPKQDESGKHSEFLTVPAGSYSLSVPGHHHQKEMRRCSSEQMPCPHPTEVPEIRSKSFDYGNLSHAPVAGTSPSTLSPSRERKKCFLVRQASFSGSPEIAQGEAGVDPSVKQEHMEHLHAGLRAAWSSVLPPLPGDDPGKQVGTCGPLSSGPPLHLTQQQIMHMDSQESLRNPLIQPTSYMTSKHLPEQPHLFPHQDAVPFSPIQNALFQFQYPTVCMVHLPAQQPPWWQTHFPHPFAPHPQNSYSKPPFQADLHSSYPLEHVAEHTGKKSADYPHAKEQTYPCYSGTSGLHSKNLPLKFPSDPGSKSTETPTEQLLREDFASENAGPLQSLPGTVVPVRIQTHVPSYGSVMYTSISQILGQNSPAIVICKVDENMTQRTLVTNAAMQGIGLNIAQVLGQHTGLEKYPLWKVPQTLPLGLESSIPLCLPSTSDNAASLGGSKRMLSPASSLELFMETKQQKRVKEEKMYGQIVEELSAVELTNSDIKKGLSRPQKPQLVRQGCASEPKDGCFQSRSSSFSSLSPSSSQDHPSASGPFPPNREILPGSRAPPRRKFSGPSESRESSDELDMDETSSDMSMSPQSSALPTGGGQQEEEGKARKLPVSMLVHMASGPGGNVANSTLLFTDVADFQQILQFPSLRTTTTVSWCFLNYTKPSFVQQATFKSSVYASWCISSCNPNPSGLNTKTTLALLRSKQKITAEIYTLAAMHRPGAGKLTSSSVWKQFAQMKPDAPFLFGNKLERKLAGNVLKERGKGEIHGDKDLGSKQTEPIRIKIFEGGYKSNEDYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYVCKLCNFAFKTKGNLTKHMKSKAHMKKCLELGVSMTSVDDTETEEAENMEELHKTSEKHSMSGISTDHQFSDAEESDGEDGDDNDDDDEDDDDFDDQGDLTPKTRSRSTSPQPPRFSSLPVNVGAVAHGVPSDSSLGHSSLISYLVTLPSIQVTQLMTPSDSCDDTQMTEYQRLFQSKSTDSEPDKDRLDIPSSMDEEAMLSSEPSSSPRDFSPSSYRSSPGYDSSPCRDNSPKRYLIPKGDLSPRRHLSPRRDLSPMRHLSPRKEAALRREMSQGDASPRRHLSPRRPLSPGKDITARRDLSPRRERRYMTTIRAPSPRRALYPNPPLSMGQYLQTEPIVLGPPNLRRGIPQVPYFSLYGDQEGAYEHHGSSLFPEGPTDYVFSHLPLHSQQQVRAPIPMVPVGGIQMVHSLPPALSGLHPPPTLPLPTEGSEEKKGAPGEAFAKDPYILSRRHEKQAPQVLQSSGLPSSPSSPRLLMKQSTSEDSLNSTEREQEENIQTCTKAIASLRIATEEAALLGADPPTWVQESPQKPLESAHVSIRHFGGPEPGQPCTSAAHPDLHDGEKDTFGTSQTAVAHPTFYSKSSVDEKRVDFQSSKELSLSTEEGNEPSPEKNQLH", "length": 2430 }, "evidence": [ { "id": "RGD:61988", "url": "https://alliancegenome.org/gene/RGD:61988#orthology", "database": "AGR" }, { "id": "HGNC:4921", "url": "https://alliancegenome.org/gene/HGNC:4921#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-562", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-562#orthology", "database": "AGR" }, { "id": "MGI:1338076", "url": "https://alliancegenome.org/gene/MGI:1338076#orthology", "database": "AGR" }, { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5T1R4-1", "protein_name": "Transcription factor HIVEP3", "gene_name": "HIVEP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPEQSVKGTKKAEGSPRKRLTKGEAIQTSVSSSVPYPGSGTAATQESPAQELLAPQPFPGPSSVLREGSQEKTGQQQKPPKRPPIEASVHISQLPQHPLTPAFMSPGKPEHLLEGSTWQLVDPMRPGPSGSFVAPGLHPQSQLLPSHASIIPPEDLPGVPKVFVPRPSQVSLKPTEEAHKKERKPQKPGKYICQYCSRPCAKPSVLQKHIRSHTGERPYPCGPCGFSFKTKSNLYKHRKSHAHRIKAGLASGMGGEMYPHGLEMERIPGEEFEEPTEGESTDSEEETSATSGHPAELSPRPKQPLLSSGLYSSGSHSSSHERCSLSQSSTAQSLEDPPPFVEPSSEHPLSHKPEDTHTIKQKLALRLSERKKVIDEQAFLSPGSKGSTESGYFSRSESAEQQVSPPNTNAKSYAEIIFGKCGRIGQRTAMLTATSTQPLLPLSTEDKPSLVPLSVPRTQVIEHITKLITINEAVVDTSEIDSVKPRRSSLSRRSSMESPKSSLYREPLSSHSEKTKPEQSLLSLQHPPSTAPPVPLLRSHSMPSAACTISTPHHPFRGSYSFDDHITDSEALSHSSHVFTSHPRMLKRQPAIELPLGGEYSSEEPGPSSKDTASKPSDEVEPKESELTKKTKKGLKTKGVIYECNICGARYKKRDNYEAHKKYYCSELQIAKPISAGTHTSPEAEKSQIEHEPWSQMMHYKLGTTLELTPLRKRRKEKSLGDEEEPPAFESTKSQFGSPGPSDAARNLPLESTKSPAEPSKSVPSLEGPTGFQPRTPKPGSGSESGKERRTTSKEISVIQHTSSFEKSDSLEQPSGLEGEDKPLAQFPSPPPAPHGRSAHSLQPKLVRQPNIQVPEILVTEEPDRPDTEPEPPPKEPEKTEEFQWPQRSQTLAQLPAEKLPPKKKRLRLAEMAQSSGESSFESSVPLSRSPSQESNVSLSGSSRSASFERDDHGKAEAPSPSSDMRPKPLGTHMLTVPSHHPHAREMRRSASEQSPNVSHSAHMTETRSKSFDYGSLSLTGPSAPAPVAPPARVAPPERRKCFLVRQASLSRPPESELEVAPKGRQESEEPQPSSSKPSAKSSLSQISSAATSHGGPPGGKGPGQDRPPLGPTVPYTEALQVFHHPVAQTPLHEKPYLPPPVSLFSFQHLVQHEPGQSPEFFSTQAMSSLLSSPYSMPPLPPSLFQAPPLPLQPTVLHPGQLHLPQLMPHPANIPFRQPPSFLPMPYPTSSALSSGFFLPLQSQFALQLPGDVESHLPQIKTSLAPLATGSAGLSPSTEYSSDIRLPPVAPPASSSAPTSAPPLALPACPDTMVSLVVPVRVQTNMPSYGSAMYTTLSQILVTQSQGSSATVALPKFEEPPSKGTTVCGADVHEVGPGPSGLSEEQSRAFPTPYLRVPVTLPERKGTSLSSESILSLEGSSSTAGGSKRVLSPAGSLELTMETQQQKRVKEEEASKADEKLELVKPCSVVLTSTEDGKRPEKSHLGNQGQGRRELEMLSSLSSDPSDTKEIPPLPHPALSHGTAPGSEALKEYPQPSGKPHRRGLTPLSVKKEDSKEQPDLPSLAPPSSLPLSETSSRPAKSQEGTDSKKVLQFPSLHTTTNVSWCYLNYIKPNHIQHADRRSSVYAGWCISLYNPNLPGVSTKAALSLLRSKQKVSKETYTMATAPHPEAGRLVPSSSRKPRMTEVHLPSLVSPEGQKDLARVEKEEERRGEPEEDAPASQRGEPARIKIFEGGYKSNEEYVYVRGRGRGKYVCEECGIRCKKPSMLKKHIRTHTDVRPYVCKHCHFAFKTKGNLTKHMKSKAHSKKCQETGVLEELEAEEGTSDDLFQDSEGREGSEAVEEHQFSDLEDSDSDSDLDEDEDEDEEESQDELSRPSSEAPPPGPPHALRADSSPILGPQPPDAPASGTEATRGSSVSEAERLTASSCSMSSQSMPGLPWLGPAPLGSVEKDTGSALSYKPVSPRRPWSPSKEAGSRPPLARKHSLTKNDSSPQRCSPAREPQASAPSPPGLHVDPGRGMGALPCGSPRLQLSPLTLCPLGRELAPRAHVLSKLEGTTDPGLPRYSPTRRWSPGQAESPPRSAPPGKWALAGPGSPSAGEHGPGLGLDPRVLFPPAPLPHKLLSRSPETCASPWQKAESRSPSCSPGPAHPLSSRPFSALHDFHGHILARTEENIFSHLPLHSQHLTRAPCPLIPIGGIQMVQARPGAHPTLLPGPTAAWVSGFSGGGSDLTGAREAQERGRWSPTESSSASVSPVAKVSKFTLSSELEGGDYPKERERTGGGPGRPPDWTPHGTGAPAEPTPTHSPCTPPDTLPRPPQGRRAAQSWSPRLESPRAPTNPEPSATPPLDRSSSVGCLAEASARFPARTRNLSGEPRTRQDSPKPSGSGEPRAHPHQPEDRVPPNA", "length": 2406 }, "evidence": [ { "id": "FB:FBgn0003396", "url": "https://alliancegenome.org/gene/FB:FBgn0003396#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEH8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEH8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEH8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH8" } ], "pmid": "" }, { "name": "developmental process", "id": "GO:0032502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032502", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEH8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEH8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH8" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEH8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH8" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEH8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1003, "end_pos": 1005, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1210, "end_pos": 1212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1215, "end_pos": 1217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1392, "end_pos": 1394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 570, "end_pos": 572, "annotation": "n_glycosylation_sequon" }, { "start_pos": 759, "end_pos": 761, "annotation": "n_glycosylation_sequon" }, { "start_pos": 871, "end_pos": 873, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PEH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEH8" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 120, "end_pos": 147, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1414 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1003, "end_pos": 1005 }, { "start_pos": 1210, "end_pos": 1212 }, { "start_pos": 1215, "end_pos": 1217 }, { "start_pos": 1392, "end_pos": 1394 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 570, "end_pos": 572 }, { "start_pos": 759, "end_pos": 761 }, { "start_pos": 871, "end_pos": 873 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PEI5-1", "uniprot_ac": "A0A8M9PEI5", "uniprot_id": "A0A8M9PEI5_DANRE", "mass": { "chemical_mass": 65532.0, "monoisotopic_mass": 65532.0 }, "refseq": { "ac": "XP_021322964", "name": "kelch-like protein 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322964" }, "gene_names": [ { "name": "klhl10b.1", "type": "recommended", "evidence": [ { "id": "A0A8M9PEI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEI5" } ] }, { "name": "klhl10b.1", "type": "synonym", "evidence": [ { "id": "XP_021322964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322964" } ] } ], "protein_names": [ { "name": "Kelch-like protein 10", "type": "synonym", "evidence": [ { "id": "A0A8M9PEI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEI5/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 10", "type": "synonym", "evidence": [ { "id": "XP_021322964", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322964" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021322964.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322964" } ] } ], "disease": [ { "disease_id": "DOID:0070180", "recommended_name": { "id": "DOID:0070180", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070180", "name": "spermatogenic failure 11", "description": "A spermatogenic failure that is characterized by autosomal dominant inheritance of oligozoospermia and in some cases teratozoospermia and/or moderate asthenozoospermia that has_material_basis_in mutation in the KLHL10 gene on chromosome 17q21." }, "synonyms": [ { "id": "DOID:0070180", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070180", "name": "SPGF11", "description": "" }, { "id": "MONDO:0014037", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014037", "name": "spermatogenic failure 11", "description": "Any azoospermia in which the cause of the disease is a mutation in the KLHL10 gene." }, { "id": "MONDO:0014037", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014037", "name": "KLHL10 azoospermia", "description": "" }, { "id": "MONDO:0014037", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014037", "name": "azoospermia caused by mutation in KLHL10", "description": "" }, { "id": "MONDO:0014037", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014037", "name": "spermatogenic failure 11", "description": "" }, { "id": "MONDO:0014037", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014037", "name": "spermatogenic failure type 11", "description": "" }, { "id": "MONDO:0014037", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014037", "name": "SPGF11", "description": "" }, { "id": "MIM:615081", "resource": "MIM", "url": "https://www.omim.org/entry/615081", "name": "Spermatogenic failure 11", "description": "Spermatogenic failure 11" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070180", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070180" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEI5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEI5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "klhl10b.1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEI5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131015-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131015-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PEI5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PEI5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18240", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18240", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18450", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18450", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "560378", "url": "https://www.ncbi.nlm.nih.gov/gene/560378", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030608", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030608", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:560378", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560378", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PEI5", "url": "https://www.orthodb.org/?gene=A0A8M9PEI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF172", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF172", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322964", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322964", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PEI5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PEI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131015-2", "url": "https://zfin.org/ZDB-GENE-131015-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MENFNSPTASNVFDEARLLGEHTDLIIRANGTKFQVHKIIMCACSPYFRVLFSSKWTSTAEHTYDIPEMSPDILYLIIQYAYTRSALITAENVLKLLVTADQLLISGLVAACCQFLDTHLGPENCIGIHMITKDFHSCSKLHHKAKRFILQHFENVLQVSEEFLELPLEELEEIIDDDKLNVRHEEVVFEAILHWIDHEPESRRKHIATLLPKVRLGLMTLQYFMDNVKHNPLVMENEACKPIILSAMKALFDFQFDGPISSELLHRLTRPRLPSAILLAIGGWSNGPTNEIEAFDMRAEQWVNVNKVDERSTAYLGTAVLEEFVYCIGGYDSVEYFNNVRKFNLITQTWHEVAPMYERRCYVSVAVLDGLIYAIGGFDGLERLNSAECYNPDTNQWTLTAQMNERRSDASASSLQGKVYICGGFTGTECLFSAECFNPQTNQWTLIAPMRSRRSGLGVIAYDGLVYAVGGFDGASRLRTAEAYNPLTNMWRDVASMHKTRSNFGIEVVDDQLFAVGGFDGSGTISDVDCYDVEMDEWYSVNKASISRSALSCCVATGLPNIIQYVAQRDAVQIQDESDNE", "length": 581, "header": "tr|A0A8M9PEI5-1|A0A8M9PEI5_DANRE Isoform 1 of Kelch-like protein 10 OS=Danio rerio OX=7955 GN=klhl10b.1 PE=4 SV=2 CANONICAL=A0A8M9PEI5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PEI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEI5/entry#A0A8M9PEI5-1", "sequence": { "sequence": "MENFNSPTASNVFDEARLLGEHTDLIIRANGTKFQVHKIIMCACSPYFRVLFSSKWTSTAEHTYDIPEMSPDILYLIIQYAYTRSALITAENVLKLLVTADQLLISGLVAACCQFLDTHLGPENCIGIHMITKDFHSCSKLHHKAKRFILQHFENVLQVSEEFLELPLEELEEIIDDDKLNVRHEEVVFEAILHWIDHEPESRRKHIATLLPKVRLGLMTLQYFMDNVKHNPLVMENEACKPIILSAMKALFDFQFDGPISSELLHRLTRPRLPSAILLAIGGWSNGPTNEIEAFDMRAEQWVNVNKVDERSTAYLGTAVLEEFVYCIGGYDSVEYFNNVRKFNLITQTWHEVAPMYERRCYVSVAVLDGLIYAIGGFDGLERLNSAECYNPDTNQWTLTAQMNERRSDASASSLQGKVYICGGFTGTECLFSAECFNPQTNQWTLIAPMRSRRSGLGVIAYDGLVYAVGGFDGASRLRTAEAYNPLTNMWRDVASMHKTRSNFGIEVVDDQLFAVGGFDGSGTISDVDCYDVEMDEWYSVNKASISRSALSCCVATGLPNIIQYVAQRDAVQIQDESDNE", "length": 581, "header": "tr|A0A8M9PEI5-1|A0A8M9PEI5_DANRE Isoform 1 of Kelch-like protein 10 OS=Danio rerio OX=7955 GN=klhl10b.1 PE=4 SV=2 CANONICAL=A0A8M9PEI5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:560378", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560378", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6Z1K9-1", "protein_name": "Kelch-like protein 10 isoform X1", "gene_name": "klhl10a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMDPAFEVFNEVRLQGEHTDVDINVHGKVFRVHKIILCGCSPYFRMLFSTQWTKPKQHFNFPEMSSDTMSLIIQHAYARPVQITEDNVCELLVAADQLLISGLTEACCKFLEANFSLQNCIGIWAFTERFHSCTELHHKAEFYVLQHFQEVQQVSEEFLQLPLELLENMISRDELNVKQEEVVFEAILRWINHEPENRRNHITALLSRVRLGLMSPEYFMNNVRNNPLVLENEACSFIIINAMKVIFDLHVEPTSSGLVSYMTRQRMPSEVLLAIGGWSIGNPTNGIEAYDTRANCWKDVTVENELPRAYHGVAVLDGFIYAVGGFDSENYFSSVRKFNPVTHTWHEVAPMYERRCYVSVAVLDGLLYAIGGFNGHARLKTAECYNKNTNQWTQISPMSERRSDASATSLHGKVYICGGFTGVECLFTAESFNPETNQWSLIEPMRTRRSGVGVITFGNLIYAVGGFDGSSRLRSVEAYDPHTDSWHDIESMINTRSNFGIEVVNDQLIVVGGFNGFRTCSDVEIYNQSTNEWVEVCDMNISRSALSCCVISGLPQCLQYVFDRDSLPMLEEESDESNQE", "length": 580 }, "evidence": [ { "id": "RGD:1303290", "url": "https://alliancegenome.org/gene/RGD:1303290#orthology", "database": "AGR" }, { "id": "HGNC:18829", "url": "https://alliancegenome.org/gene/HGNC:18829#orthology", "database": "AGR" }, { "id": "MGI:2181067", "url": "https://alliancegenome.org/gene/MGI:2181067#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6JEL2-1", "protein_name": "Kelch-like protein 10", "gene_name": "KLHL10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEMESAAASTRFHQPHMERKMSAMACEIFNELRLEGKLCDVVIKVNGFEFSAHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAILKWISHDPQNRKQHISILLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINALKAMYDLNMNGPSNSDFTNPLTRPRLPYAILFAIGGWSGGSPTNAIEAYDARADRWVNVTCEEESPRAYHGAAYLKGYVYIIGGFDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLGNFIYAMGGFDGYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGGFNGNECLFTAEVYNTESNQWTVIAPMRSRRSGIGVIAYGEHVYAVGGFDGANRLRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFTTTFNVECYDEKTDEWYDAHDMSIYRSALSCCVVPGLANVEEYAARRDNFPGLALRDEVKYSASTSTLPV", "length": 608 }, "evidence": [ { "id": "RGD:1303290", "url": "https://alliancegenome.org/gene/RGD:1303290#orthology", "database": "AGR" }, { "id": "HGNC:18829", "url": "https://alliancegenome.org/gene/HGNC:18829#orthology", "database": "AGR" }, { "id": "MGI:2181067", "url": "https://alliancegenome.org/gene/MGI:2181067#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131015-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131015-2#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6JEL3-1", "protein_name": "Kelch-like protein 10", "gene_name": "Klhl10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEMESSAASTRFHQPHMERKMSAMTCEIFNELRLEGKLCDVVIKVNGFEFNAHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAILKWISHDPQNRKQHISVLLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINALKAMYDLNMNGPSNSDFTNPLTRPRLPYAILFAIGGWSGGSPTNAIEAYDARADRWVNVTCEEESPRAYHGAAYLKGYVYIIGGFDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLSNFIYAMGGFDGYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGGFNGNECLFTAEVYNTESNQWTVIAPMRSRRSGIGVIAYGEHVYAVGGFDGANRLRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFTTTFNVECYDEKTDEWYDAHDMSIYRSALSCCVVPGLANVGEYAARRDNFTGLALRDEVKYSASTSTLPV", "length": 608 }, "evidence": [ { "id": "RGD:1303290", "url": "https://alliancegenome.org/gene/RGD:1303290#orthology", "database": "AGR" }, { "id": "HGNC:18829", "url": "https://alliancegenome.org/gene/HGNC:18829#orthology", "database": "AGR" }, { "id": "MGI:2181067", "url": "https://alliancegenome.org/gene/MGI:2181067#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131015-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131015-2#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D5V2-1", "protein_name": "Kelch-like protein 10", "gene_name": "Klhl10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMESTAASTRFHQPHMERKMSAMTCEIFNELRLEGKLCDVVIKVNGFEFNAHKNILCSCSSYFRALFTSGWNNTEKKVYNIPGISPDMMKLIIEYAYTRTVPITPDNVEKLLAAADQFNIMGIVRGCCEFLKSELCLDNCIGICKFTDYYYCPELRQKAYMFILHNFEEMVKVSAEFLELSVTELKDIIEKDELNVKQEDAVFEAILKWISHDPQNRKQHISVLLPKVRLALMHAEYFMNNVKMNDYVKDSEECKPVIINALKAMYDLNMNGPSNSDFTNPLTRPRLPYAILFAIGGWSGGSPTNAIEAYDARADRWVNVTCEEESPRAYHGAAYLKGYVYIIGGFDSVDYFNSVKRFDPVKKTWHQVAPMHSRRCYVSVTVLSNFIYAMGGFDGYVRLNTAERYEPETNQWTLIAPMHEQRSDASATTLYGKVYICGGFNGNECLFTAEVYNTESNQWTVIAPMRSRRSGIGVIAYGEHVYAVGGFDGANRLRSAEAYSPVANTWRTIPTMFNPRSNFGIEVVDDLLFVVGGFNGFTTTFNVECYDEKTDEWYDAHDMSIYRSALSCCVVPGLANVGEYAARRDNFTGLALRDEVKYSASTSTLPV", "length": 608 }, "evidence": [ { "id": "RGD:1303290", "url": "https://alliancegenome.org/gene/RGD:1303290#orthology", "database": "AGR" }, { "id": "HGNC:18829", "url": "https://alliancegenome.org/gene/HGNC:18829#orthology", "database": "AGR" }, { "id": "MGI:2181067", "url": "https://alliancegenome.org/gene/MGI:2181067#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131015-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131015-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PEI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEI5" }, { "id": "PS50097", "database": "PROSITE", "url": 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[ "Protein" ] } ], "sequence": { "sequence": "MDGITDEHEQGINLSELPKLRLVLIGVTESGKSAVGNAILGKKAFDEVGVKTRVCFARQGLVRGRQVQVVDTPGWEWFKVNGSSTSLWFVKKEMMMSMSLCQPGAHALLLVVPLSFSFSQRERHAVEEHIELFGQEAWRHSLVLFTILDRKQLRGSSLKQEVELNVELYKLVEKCGGRFHALYSNPKAGEDQVADLLAKITKMMETNGETMISSKNVLEKVKEMEKEEERKLEEERKLKEENLQKVREALKAKELRRSRRRMEQQTLDGVEQKGWAGDNQSNKIPLDEGGSNSLLSCKQQ", "length": 300, "header": "tr|A0A8M9PER5-1|A0A8M9PER5_DANRE Isoform 1 of GTPase IMAP family member 8 OS=Danio rerio OX=7955 GN=LOC798736 PE=3 SV=1 CANONICAL=A0A8M9PER5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PER5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PER5/entry#A0A8M9PER5-1", "sequence": { "sequence": "MDGITDEHEQGINLSELPKLRLVLIGVTESGKSAVGNAILGKKAFDEVGVKTRVCFARQGLVRGRQVQVVDTPGWEWFKVNGSSTSLWFVKKEMMMSMSLCQPGAHALLLVVPLSFSFSQRERHAVEEHIELFGQEAWRHSLVLFTILDRKQLRGSSLKQEVELNVELYKLVEKCGGRFHALYSNPKAGEDQVADLLAKITKMMETNGETMISSKNVLEKVKEMEKEEERKLEEERKLKEENLQKVREALKAKELRRSRRRMEQQTLDGVEQKGWAGDNQSNKIPLDEGGSNSLLSCKQQ", "length": 300, "header": "tr|A0A8M9PER5-1|A0A8M9PER5_DANRE Isoform 1 of GTPase IMAP family member 8 OS=Danio rerio OX=7955 GN=LOC798736 PE=3 SV=1 CANONICAL=A0A8M9PER5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:798736", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798736", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PER5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PER5" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PER5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PER5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 4, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PER5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PER5" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PER5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PER5" } ], "pmid": "" }, { "name": "Golgi apparatus", "id": "GO:0005794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005794", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PER5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PER5" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PER5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PER5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PER5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PER5" }, { "id": "PS51720", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51720" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AIG1-type G", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 221, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PEZ4-1", "uniprot_ac": "A0A8M9PEZ4", "uniprot_id": "A0A8M9PEZ4_DANRE", "mass": { "chemical_mass": 44869.0, "monoisotopic_mass": 44869.0 }, "refseq": { "ac": "XP_021323144", "name": "cytosolic 5'-nucleotidase 1A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323144" }, "gene_names": [ { "name": "nt5c1ab", "type": "recommended", "evidence": [ { "id": "A0A8M9PEZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4" } ] }, { "name": "nt5c1ab", "type": "synonym", "evidence": [ { "id": "XP_021323144", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323144" } ] } ], "protein_names": [ { "name": "Cytosolic 5'-nucleotidase 1A isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PEZ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4/entry#names_and_taxonomy" } ] }, { "name": "cytosolic 5'-nucleotidase 1A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323144", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323144" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323144.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323144", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323144" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nt5c1ab", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131120-153", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-153", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PEZ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PEZ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "799449", "url": "https://www.ncbi.nlm.nih.gov/gene/799449", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:799449", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799449", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PEZ4", "url": "https://www.orthodb.org/?gene=A0A8M9PEZ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31367", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31367", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31367:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31367:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323144", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323144", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PEZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PEZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPD5", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPD5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPF6", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPF6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131120-153", "url": "https://zfin.org/ZDB-GENE-131120-153", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSIKRLKILEAPADTKQTRGLDVVTVTAFAAVMPPENKHGQVGGKRLILHPLLGNKSTSSLWERRIMQAKIGKENLPKPQNAITIAVSSRALFNMDLEQDIYEQQGMEDYLNYQIQHEMEPFAPGPAFPFIKAVEAVNTRLRELYPDSEELFDVVLMTSNHAHVGLRLINSINHHQLFLERFCMTGGNSPIGYLKAYHTNLYLSADSLKVREAIEAGIAAATVFSPGKITEVPETQLRVAFDGDAVLFSDESERIYKAHGLDKFFEHEKAHENKPLDHGPLKGFLEALGKLQQKFYAKGQRLDCPIRTYLVTARSAASSGTRALKTLRSWGLETDEALFLAGAPKGPMLEKIRPHIFFDDQMFHVEGAAELGTVAAHVPYGIAQKIPPKKDGKKDTSARQLE", "length": 403, "header": "tr|A0A8M9PEZ4-1|A0A8M9PEZ4_DANRE Isoform 1 of Cytosolic 5'-nucleotidase 1A isoform X1 OS=Danio rerio OX=7955 GN=nt5c1ab PE=4 SV=3 CANONICAL=A0A8M9PEZ4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PEZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4/entry#A0A8M9PEZ4-1", "sequence": { "sequence": "MSSIKRLKILEAPADTKQTRGLDVVTVTAFAAVMPPENKHGQVGGKRLILHPLLGNKSTSSLWERRIMQAKIGKENLPKPQNAITIAVSSRALFNMDLEQDIYEQQGMEDYLNYQIQHEMEPFAPGPAFPFIKAVEAVNTRLRELYPDSEELFDVVLMTSNHAHVGLRLINSINHHQLFLERFCMTGGNSPIGYLKAYHTNLYLSADSLKVREAIEAGIAAATVFSPGKITEVPETQLRVAFDGDAVLFSDESERIYKAHGLDKFFEHEKAHENKPLDHGPLKGFLEALGKLQQKFYAKGQRLDCPIRTYLVTARSAASSGTRALKTLRSWGLETDEALFLAGAPKGPMLEKIRPHIFFDDQMFHVEGAAELGTVAAHVPYGIAQKIPPKKDGKKDTSARQLE", "length": 403, "header": "tr|A0A8M9PEZ4-1|A0A8M9PEZ4_DANRE Isoform 1 of Cytosolic 5'-nucleotidase 1A isoform X1 OS=Danio rerio OX=7955 GN=nt5c1ab PE=4 SV=3 CANONICAL=A0A8M9PEZ4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HPD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4/entry#A0AC58HPD5-1", "sequence": { "sequence": "MRVCVCRSYRAELLYDHQLFMMNMNTALPKEMHTFWEKETCNQSSPSKKPKPPKPQNAITIAVSSRALFNMDLEQDIYEQQGMEDYLNYQIQHEMEPFAPGPAFPFIKFCSSSEEVMMDVLLVCVVQAVEAVNTRLRELYPDSEELFDVVLMTSNHAHVGLRLINSINHHQLFLERFCMTGGNSPIGYLKAYHTNLYLSADSLKVREAIEAGIAAATVFSPGKITEVPETQLRVAFDGDAVLFSDESERIYKAHGLDKFFEHEKAHENKPLDHGPLKGFLEALGKLQQKFYAKGQRLDCPIRTYLVTARSAASSGTRALKTLRSWGLETDEALFLAGAPKGPMLEKIRPHIFFDDQMFHVEGAAELGTVAAHVPYGIAQKIPPKKDGKKDTSARQLE", "length": 397, "header": "tr|A0AC58HPD5-1|A0AC58HPD5_DANRE Computationally mapped isoform of Cytosolic 5'-nucleotidase 1A isoform X3 OS=Danio rerio OX=7955 GN=nt5c1ab PE=4 SV=1 CANONICAL=A0A8M9PEZ4-1" }, "locus": {} }, { "isoform_ac": "A0AC58HPF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4/entry#A0AC58HPF6-1", "sequence": { "sequence": "MRVCVCRSYRAELLYDHQLFMMNMNTALPKEMHTFWEKETCNQSSPSKKPKPPKPQNAITIAVSSRALFNMDLEQDIYEQQGMEDYLNYQIQHEMEPFAPGPAFPFIKAVEAVNTRLRELYPDSEELFDVVLMTSNHAHVGLRLINSINHHQLFLERFCMTGGNSPIGYLKAYHTNLYLSADSLKVREAIEAGIAAATVFSPGKITEVPETQLRVAFDGDAVLFSDESERIYKAHGLDKFFEHEKAHENKPLDHGPLKGFLEALGKLQQKFYAKGQRLDCPIRTYLVTARSAASSGTRALKTLRSWGLETDEALFLAGAPKGPMLEKIRPHIFFDDQMFHVEGAAELGTVAAHVPYGIAQKIPPKKDGKKDTSARQLE", "length": 378, "header": "tr|A0AC58HPF6-1|A0AC58HPF6_DANRE Computationally mapped isoform of Cytosolic 5'-nucleotidase 1A isoform X2 OS=Danio rerio OX=7955 GN=nt5c1ab PE=4 SV=1 CANONICAL=A0A8M9PEZ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:799449", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799449", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286Y9C9-1", "protein_name": "5'-nucleotidase, cytosolic IAa isoform X1", "gene_name": "nt5c1aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLDPVQVMKGQEPMPNTCPSASNGDTKASWEDSNKDMLENVGSKKPKSGPVRRARKVEGGIFFPKPENAVTIAVSSRVMFRTEKEQKVFEQKGIEEYLRYQVEHENEPFAPGPAFPFVKALEAVNTRLRELYPESEELFDIVLVTYNHAHVGVRLINTINYHNLFIERFCMTGGSSPIGYLKAFHTNLYLSADAEKVQEALSEGIAAATMFMPEKQIEVSETQLRVAFDGDAVLFSDESERIFKAHGLDKFFEHERENENRLLDHGPLKGFLEVLGKLQKKFYAKGHRLDCPIRTYLVTARSAASSGIRALKTLRAWGLETDEALFLAGAPKGPMLEKIRPHIYFDDQMFHVEGAVEMGAIAAHVPYGIAQKYPHKKSSNTAK", "length": 384 }, "evidence": [ { "id": "RGD:1310908", "url": "https://alliancegenome.org/gene/RGD:1310908#orthology", "database": "AGR" }, { "id": "MGI:2155700", "url": "https://alliancegenome.org/gene/MGI:2155700#orthology", "database": "AGR" }, { "id": "HGNC:17819", "url": "https://alliancegenome.org/gene/HGNC:17819#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8I5ZYY7-1", "protein_name": "5'-nucleotidase, cytosolic IA", "gene_name": "Nt5c1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGRLGRAGGAGSLALPPGPAACLSHPGRASLPRLSSLSSLSPTLSSPARPDRIRAGTWNQGSPRRPENPDQGQRPPRCRAGRKPRRSMTISRPRRNPNRPWLILVTEIVSCGLPVSGVWSVPTEAPEMVDSQPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNKQLRELYPDSEDIFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSKDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQNPRREKQSLGAQ", "length": 454 }, "evidence": [ { "id": "RGD:1310908", "url": "https://alliancegenome.org/gene/RGD:1310908#orthology", "database": "AGR" }, { "id": "MGI:2155700", "url": "https://alliancegenome.org/gene/MGI:2155700#orthology", "database": "AGR" }, { "id": "HGNC:17819", "url": "https://alliancegenome.org/gene/HGNC:17819#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-153", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-153#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A3KFX0-1", "protein_name": "Cytosolic 5'-nucleotidase 1A", "gene_name": "Nt5c1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGQPREAREPGPGAETAAVPRWEEAKTFYDNLSSKKKPKSPKPQNAVTIAVSSRALFRMDEEQRIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNKRLRELYPDSEDIFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADADKVREAIDEGIAAATIFSPSRDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQNPRRAAAAKQSLGAQ", "length": 365 }, "evidence": [ { "id": "RGD:1310908", "url": "https://alliancegenome.org/gene/RGD:1310908#orthology", "database": "AGR" }, { "id": "MGI:2155700", "url": "https://alliancegenome.org/gene/MGI:2155700#orthology", "database": "AGR" }, { "id": "HGNC:17819", "url": "https://alliancegenome.org/gene/HGNC:17819#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-153", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-153#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BXI3-1", "protein_name": "Cytosolic 5'-nucleotidase 1A", "gene_name": "NT5C1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPGQPREPQEPREPGPGAETAAAPVWEEAKIFYDNLAPKKKPKSPKPQNAVTIAVSSRALFRMDEEQQIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNRRLRELYPDSEDVFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSRDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQTPRRTAPAKQAPSAQ", "length": 368 }, "evidence": [ { "id": "RGD:1310908", "url": "https://alliancegenome.org/gene/RGD:1310908#orthology", "database": "AGR" }, { "id": "MGI:2155700", "url": "https://alliancegenome.org/gene/MGI:2155700#orthology", "database": "AGR" }, { "id": "HGNC:17819", "url": "https://alliancegenome.org/gene/HGNC:17819#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131120-153", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131120-153#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "magnesium ion binding", "id": "GO:0000287", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000287", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4" } ], "pmid": "" }, { "name": "nucleotide binding", "id": "GO:0000166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000166", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4" } ], "pmid": "" }, { "name": "5'-nucleotidase activity", "id": "GO:0008253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008253", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "nucleotide metabolic process", "id": "GO:0009117", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009117", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4" } ], "pmid": "" }, { "name": "adenosine metabolic process", "id": "GO:0046085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046085", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PEZ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PEZ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PF33-1", "uniprot_ac": "A0A8M9PF33", "uniprot_id": "A0A8M9PF33_DANRE", "mass": { "chemical_mass": 49706.0, "monoisotopic_mass": 49706.0 }, "refseq": { "ac": "XP_021323189", "name": "uncharacterized protein wu:fe17e08", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323189" }, "gene_names": [ { "name": "wu:fe17e08", "type": "synonym", "evidence": [ { "id": "XP_021323189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323189" }, { "id": "A0A8M9PF33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF33" } ] } ], "protein_names": [ { "name": "Uncharacterized protein wu:fe17e08", "type": "synonym", "evidence": [ { "id": "A0A8M9PF33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF33/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein wu:fe17e08", "type": "synonym", "evidence": [ { "id": "XP_021323189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323189" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323189" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF33", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF33#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF33", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF33" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF33", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-4988", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4988", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PF33", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PF33", "database": "AlphaFoldDB", "categories": [] }, { "id": "326789", "url": "https://www.ncbi.nlm.nih.gov/gene/326789", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:326789", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:326789", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PF33", "url": "https://www.orthodb.org/?gene=A0A8M9PF33", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323189", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PF33", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF33", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PF33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF33-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-4988", "url": "https://zfin.org/ZDB-GENE-030131-4988", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMACIKQENEGIQIVDVFTLREQHTDLTGLKEENEDEDQNETHQEVITEDKYSQTSQQRVYKTETRSLFICQQCGKSFNTERKLKVHMKIHREKPFTCAHCGKSVGAKGKLEIHMRTHAGEKPYSCQQCSKSFSTQRNLSEHKREHSREKPFTCDECGKSFRQLRTLQVHTRTHTEEKHDCPECGKSFGKRGNLKTHMKTHLEKKLFACQQCEKSFRKKFKLEIHMRTHTGEKPYSCQQCSKSFARSDSLRSHMLTHSQEKRFICEHCGMAFNRSARLKLHMDTHVAENSTSCPQCGKSFAHPNGLKLHMSAHSGEKPFRCDQCGKGFLHSANLKAHMSSHTGEKPFTCAQCGKSFTNRGSFYTHMRSHSGEKPYSCNLCGKTWNQKTNLKIHMRVHTGEKPFRCDQCGKRFTRKESLKKHTGANCFMSPA", "length": 431, "header": "tr|A0A8M9PF33-1|A0A8M9PF33_DANRE Isoform 1 of Uncharacterized protein wu:fe17e08 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=A0A8M9PF33-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PF33-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF33/entry#A0A8M9PF33-1", "sequence": { "sequence": "MMACIKQENEGIQIVDVFTLREQHTDLTGLKEENEDEDQNETHQEVITEDKYSQTSQQRVYKTETRSLFICQQCGKSFNTERKLKVHMKIHREKPFTCAHCGKSVGAKGKLEIHMRTHAGEKPYSCQQCSKSFSTQRNLSEHKREHSREKPFTCDECGKSFRQLRTLQVHTRTHTEEKHDCPECGKSFGKRGNLKTHMKTHLEKKLFACQQCEKSFRKKFKLEIHMRTHTGEKPYSCQQCSKSFARSDSLRSHMLTHSQEKRFICEHCGMAFNRSARLKLHMDTHVAENSTSCPQCGKSFAHPNGLKLHMSAHSGEKPFRCDQCGKGFLHSANLKAHMSSHTGEKPFTCAQCGKSFTNRGSFYTHMRSHSGEKPYSCNLCGKTWNQKTNLKIHMRVHTGEKPFRCDQCGKRFTRKESLKKHTGANCFMSPA", "length": 431, "header": "tr|A0A8M9PF33-1|A0A8M9PF33_DANRE Isoform 1 of Uncharacterized protein wu:fe17e08 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=A0A8M9PF33-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:326789", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:326789", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF33", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF33" } ], "pmid": "" }, { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF33", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF33" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF33", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PF33" } ], "pmid": "" }, { "name": "regulation of cell differentiation", "id": "GO:0045595", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045595", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PF33", "url": 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GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325588", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325588" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFB3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFB3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101885831", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFB3", "locus": {} } ], "crossref": [ { "id": "A0A8M9PFB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PFB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "101885831", "url": "https://www.ncbi.nlm.nih.gov/gene/101885831", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:101885831", "url": 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"categories": [ "Protein" ] } ], "sequence": { "sequence": "MCTPAKLRLVFGENDVRKLVLPSGIPSTLQELKSIIQETFSIPECFTLMYEDMEFGGQFFNLDSVDDVQDKCTLKVVQTEPITLNMVAMNRSTLPTESDARSCSSQDTVGLTPVSDTYLSSDSTSSGSQDTVLLSSSETTTSCRSQGWPTKFIVPTFSFDTELLLSDGNKAYQKDGTLLNNHRVTSSVLETLAETIFCYTAYPTGVQIMNVVEMLIEKYPCLKEPGSFNGQYGWQQRIKYKMGNYRAKLRGSQLSCPELEVNQKRKTNENPTPKGFKRPRKAEVNYLPPFPFGETGESLEKERLDLLNEIRKKNNKNIIGEKMEKTFYYRRTEVVKDCPAVKDFMERWPALFCESEIKNEFRRITTISLERTFLEKLDFYTPKLLALFEMKGGVAGIRIRHLLDSLSQQEDRLEDRRDVVIRCLLSFLGESAEELIEDHQDVSRDMIKDTFASHVMKIIVLSRSVEEEDASRSDVIIVIEGTEVLLGCKNLTNACLSLMGCIYSLNLSYPPKLRNTFEVFQKIFLGLDALKFSPKVNSLHRKLLM", "length": 545, "header": "tr|A0A8M9PFB3-1|A0A8M9PFB3_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC101885831 PE=4 SV=1 CANONICAL=A0A8M9PFB3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PFB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFB3/entry#A0A8M9PFB3-1", "sequence": { "sequence": 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"evidence": [ { "id": "A0A8M9PFD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6/entry#names_and_taxonomy" } ] }, { "name": "nuclear pore complex protein Nup205 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323309", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323309" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323309.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323309", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323309" } ] } ], "disease": [ { "disease_id": "DOID:0080381", "recommended_name": { "id": "DOID:0080381", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080381", "name": "nephrotic syndrome type 13", "description": "A familial nephrotic syndrome characterized by early onset of steroid-resistant nephrotic syndrome and focal segmental glomerulosclerosis that has_material_basis_in homozygous mutation in the NUP205 gene on chromosome 7q33." }, "synonyms": [ { "id": "MONDO:0014818", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014818", "name": "nephrotic syndrome, type 13", "description": "Any familial nephrotic syndrome in which the cause of the disease is a mutation in the NUP205 gene." }, { "id": "MONDO:0014818", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014818", "name": "NPHS13", "description": "" }, { "id": "MONDO:0014818", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014818", "name": "NUP205 familial nephrotic syndrome", "description": "" }, { "id": "MONDO:0014818", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014818", "name": "familial nephrotic syndrome caused by mutation in NUP205", "description": "" }, { "id": "MONDO:0014818", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014818", "name": "nephrotic syndrome, type 13", "description": "" }, { "id": "MONDO:0014818", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014818", "name": "nephrotic syndrome, type 13; NPHS13", "description": "" }, { "id": "MIM:616893", "resource": "MIM", "url": "https://www.omim.org/entry/616893", "name": "Nephrotic syndrome 13", "description": "Nephrotic syndrome 13" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080381", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080381" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFD6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nup205", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040715-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040715-8", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PFD6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PFD6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000042530", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000042530", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "445382", "url": "https://www.ncbi.nlm.nih.gov/gene/445382", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021827", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021827", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:445382", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:445382", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PFD6", "url": "https://www.orthodb.org/?gene=A0A8M9PFD6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1QJ18", "url": "https://www.orthodb.org/?gene=F1QJ18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31344", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31344", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31344:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31344:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323309", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323309", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PFD6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HT15", "url": "https://www.uniprot.org/uniprotkb/A0AC58HT15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HT15-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HT15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HT19", "url": "https://www.uniprot.org/uniprotkb/A0AC58HT19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HT19-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HT19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QJ18", "url": "https://www.uniprot.org/uniprotkb/F1QJ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QJ18-1", "url": "https://www.uniprot.org/uniprotkb/F1QJ18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040715-8", "url": "https://zfin.org/ZDB-GENE-040715-8", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MATQMAVNSGASLWGPLKELWEAVEGAIWRRQPESVHLLDLQLKKHKPYFLNLFKNPPKSAEQREKVRKASTEGIAIQGQQGARLLPEQLISEAFILSDLFDLGELAALELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCVANSLRSLIQSRHGKTFTLDLSPELVNLTTRFTDELMAQGLTKQILNLISDVSVTREFERLQKERGLGNEKHRKEVSDLIKECRQSLAECLFAWACQSPLGKDDTLALIGHLEMVTAEADGSLDSVNLALVMALLYSLDVSFLEQGTEDREDLLQALPLLTEKQYVAAVHSRLVEGQGWKLPGLQAAVQLAWALSLRALSQLPQGAALVEFTEADEALADQALLGGVFLFLTEGVLGSDGFSQEEFYTRRLHSLITDFLALMPMKVKQLRNRADEDARLIHMALQMGSEPPSSLRKDLDHLMILIGEFYSKDPFELELALEFWCPSESLQHTSLTGSFLGVPLQRPPHKQVVLSKFVRQMGDLLPATLYIPYLRMLKGLANGPQCSHYCFSLLKTNGAPHGENRQAGVSGSLVSWEHFFHSLMLYHENLRRDVPSADSTQYRHLPIRGITQRELEGLTAFLQLLTTIITWSENARLALCEHPQWTPVVVMLGLLQCSVQPVLKAQVLHVLAAFGKSPEIAASLWQSLEYTQILQTVKIPGQRQAAGIEVELNEIESSCEEYPLTRAFCHLISTLVESALPVNLGAGLRAPGFQPYLDFLRDSVFLAFPTRAYRRSAEKWEVAEAVLEVFHKLLREYEPQPSDFLPEMVELQGEQVPAHKPPGHSLMFHLLNDSPTLSLCLNLLEEGARQLDTYAQFPGKKQLESAVLHCLCLLELALQKEVTFMDLLRESQTSLLVSPLEQLLQGVSAQSRKADHITNIARYLYHSSSNPDAAFQSAKILRRITRYPNIQARLVGDFTHDQAVSERLMAGFVECLDSEEAQEGVTTNDSDSDSEKRVARIRHETKIHILNLLITSLELTGPNLGLYLLGYEVKKPVSSTNLQDPGVLGCPRSCLHAILSLLQRGSDSRSGPGLIKQAPQLAELCYQVIYQLCACPDTSGPTMRYLRTSQDFLFSHLQHLPFVLSENEIAALSQMSWLMKTTAIELRVTSLNRQRSHTQRLLNLLLDDQPHTLHTADGETGMEEENRSVSGFLQFGTVSKVRRRLLSVLDAIDFSQEAPELLQLDFFERTQIEQVITNCEHVNEQGHTVCNVKLLHRVLVAEINALQGMAAIGQRPLLMEEVNSVLQQVVERNRVRRSLSAKRHALQSWRSLVETILTACPSELIPADQRQLIIRDLLLDLHDKVLSEDAAGELMPIVAGAVFTLTAHLSQSVLSEQQGVGPEGGSGSGFASIANSALHLILRKLLDFILCTGGGFQRLRAHLYGALLYYLQIAQKPEEPETLQTGTSMWERLTAPEDCFSKLQRENLSIIESYGTALMEVVCRDACDGHEIGRMLALAVLDRVLSIDRQCQWLVYLCNSGYLRVLVESLKQDDVSLQTLLTPQPPLLKPLYIYESKMALLTRVAKTAQGAMELLRCGLVAQLVECQVFHMLPQNDALRVFGQRDPSGFIPSPLERYRQILLPTLRLMQVILTSTTAQHQQGAAQVLQWLIVHSDVIQSILHGQDMSMGSLQELSLLTAIISKTALPGALEMGQEINSAALMELQGHIGRFQRQSLSLLVRLVGTDRARYLKQIEDTVSPSNLAEKREEMEVAMQQICANIMEYCQTLLLQSSSEAQFSLCLFSPSASEPADVSIPSARVPSLGLVLLLLKNSASDFFRYHDSHRQSLNKLERVEQLPPEELKELCQGLVSGSGGVEKISSVQRNVLAKRRLVQLVNNRAKLLALCSYIIETCLFVIWRHLEFYLLYCTPTDPKDSLLPGYRGQLSLKLQDYFQMLLNDMVSYQIALCADPAGSRGLSVSRVSQQDLEQLQSDMSSSFSEPLQRKLLEVEGLYSKSRSRHTFIQALTRRIRGLVHHAKS", "length": 1999, "header": "tr|A0A8M9PFD6-1|A0A8M9PFD6_DANRE Isoform 1 of Nuclear pore complex protein Nup205 isoform X1 OS=Danio rerio OX=7955 GN=nup205 PE=1 SV=3 CANONICAL=A0A8M9PFD6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PFD6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6/entry#A0A8M9PFD6-1", "sequence": { "sequence": "MATQMAVNSGASLWGPLKELWEAVEGAIWRRQPESVHLLDLQLKKHKPYFLNLFKNPPKSAEQREKVRKASTEGIAIQGQQGARLLPEQLISEAFILSDLFDLGELAALELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCVANSLRSLIQSRHGKTFTLDLSPELVNLTTRFTDELMAQGLTKQILNLISDVSVTREFERLQKERGLGNEKHRKEVSDLIKECRQSLAECLFAWACQSPLGKDDTLALIGHLEMVTAEADGSLDSVNLALVMALLYSLDVSFLEQGTEDREDLLQALPLLTEKQYVAAVHSRLVEGQGWKLPGLQAAVQLAWALSLRALSQLPQGAALVEFTEADEALADQALLGGVFLFLTEGVLGSDGFSQEEFYTRRLHSLITDFLALMPMKVKQLRNRADEDARLIHMALQMGSEPPSSLRKDLDHLMILIGEFYSKDPFELELALEFWCPSESLQHTSLTGSFLGVPLQRPPHKQVVLSKFVRQMGDLLPATLYIPYLRMLKGLANGPQCSHYCFSLLKTNGAPHGENRQAGVSGSLVSWEHFFHSLMLYHENLRRDVPSADSTQYRHLPIRGITQRELEGLTAFLQLLTTIITWSENARLALCEHPQWTPVVVMLGLLQCSVQPVLKAQVLHVLAAFGKSPEIAASLWQSLEYTQILQTVKIPGQRQAAGIEVELNEIESSCEEYPLTRAFCHLISTLVESALPVNLGAGLRAPGFQPYLDFLRDSVFLAFPTRAYRRSAEKWEVAEAVLEVFHKLLREYEPQPSDFLPEMVELQGEQVPAHKPPGHSLMFHLLNDSPTLSLCLNLLEEGARQLDTYAQFPGKKQLESAVLHCLCLLELALQKEVTFMDLLRESQTSLLVSPLEQLLQGVSAQSRKADHITNIARYLYHSSSNPDAAFQSAKILRRITRYPNIQARLVGDFTHDQAVSERLMAGFVECLDSEEAQEGVTTNDSDSDSEKRVARIRHETKIHILNLLITSLELTGPNLGLYLLGYEVKKPVSSTNLQDPGVLGCPRSCLHAILSLLQRGSDSRSGPGLIKQAPQLAELCYQVIYQLCACPDTSGPTMRYLRTSQDFLFSHLQHLPFVLSENEIAALSQMSWLMKTTAIELRVTSLNRQRSHTQRLLNLLLDDQPHTLHTADGETGMEEENRSVSGFLQFGTVSKVRRRLLSVLDAIDFSQEAPELLQLDFFERTQIEQVITNCEHVNEQGHTVCNVKLLHRVLVAEINALQGMAAIGQRPLLMEEVNSVLQQVVERNRVRRSLSAKRHALQSWRSLVETILTACPSELIPADQRQLIIRDLLLDLHDKVLSEDAAGELMPIVAGAVFTLTAHLSQSVLSEQQGVGPEGGSGSGFASIANSALHLILRKLLDFILCTGGGFQRLRAHLYGALLYYLQIAQKPEEPETLQTGTSMWERLTAPEDCFSKLQRENLSIIESYGTALMEVVCRDACDGHEIGRMLALAVLDRVLSIDRQCQWLVYLCNSGYLRVLVESLKQDDVSLQTLLTPQPPLLKPLYIYESKMALLTRVAKTAQGAMELLRCGLVAQLVECQVFHMLPQNDALRVFGQRDPSGFIPSPLERYRQILLPTLRLMQVILTSTTAQHQQGAAQVLQWLIVHSDVIQSILHGQDMSMGSLQELSLLTAIISKTALPGALEMGQEINSAALMELQGHIGRFQRQSLSLLVRLVGTDRARYLKQIEDTVSPSNLAEKREEMEVAMQQICANIMEYCQTLLLQSSSEAQFSLCLFSPSASEPADVSIPSARVPSLGLVLLLLKNSASDFFRYHDSHRQSLNKLERVEQLPPEELKELCQGLVSGSGGVEKISSVQRNVLAKRRLVQLVNNRAKLLALCSYIIETCLFVIWRHLEFYLLYCTPTDPKDSLLPGYRGQLSLKLQDYFQMLLNDMVSYQIALCADPAGSRGLSVSRVSQQDLEQLQSDMSSSFSEPLQRKLLEVEGLYSKSRSRHTFIQALTRRIRGLVHHAKS", "length": 1999, "header": "tr|A0A8M9PFD6-1|A0A8M9PFD6_DANRE Isoform 1 of Nuclear pore complex protein Nup205 isoform X1 OS=Danio rerio OX=7955 GN=nup205 PE=1 SV=3 CANONICAL=A0A8M9PFD6-1" }, "locus": {} }, { "isoform_ac": "A0AC58HT15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6/entry#A0AC58HT15-1", "sequence": { "sequence": "MATQMAVNSGASLWGPLKELWEAVEGAIWRRQPESVHLLDLQLKKHKPYFLNLFKNPPKSAEQREKVRKASTEGIAIQGQQGARLLPEQLISEAFILSDLFDLGELAALELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCVANSLRSLIQSRHGKTFTLDLSPELVNLTTRFTDELMAQGLTKQILNLISDVSVTREFERLQKERGLGNEKHRKEVSDLIKECRQSLAECLFAWACQSPLGKDDTLALIGHLEMVTAEADGSLDSVNLALVMALLYSLDVSFLEQGTEDREDLLQALPLLTEKQYVAAVHSRLVEGQGWKLPGLQAAVQLAWALSLRALSQLPQGAALVEFTEADEALADQALLGGVFLFLTEGVLGSDGFSQEEFYTRRLHSLITDFLALMPMKVKQLRNRADEDARLIHMALQMGSEPPSSLRKDLDHLMILIGEFYSKDPFELELALEFWCPSESLQHTSLTGSFLGVPLQRPPHKQVVLSKFVRQMGDLLPATLYIPYLRMLKGLANGPQCSHYCFSLLKTNGAPHGENRQAGVSGSLVSWEHFFHSLMLYHENLRRDVPSADSTQYRHLPIRGITQRELEGLTAFLQLLTTIITWSENARLALCEHPQWTPVVVMLGLLQCSVQPVLKAQVLHVLAAFGKSPEIAASLWQSLEYTQILQTVKIPGQRQAAGIEVELNEIESSCEEYPLTRAFCHLISTLVESALPVNLGAGLRAPGFQPYLDFLRDSVFLAFPTRAYRRSAEKWEVAEAVLEVFHKLLREYEPQPSDFLPEMVELQGEQVPAHKPPGHSLMFHLLNDSPTLSLCLNLLEEGARQLDTYAQFPGKKQLESAVLHCLCLLELALQKEVTFMDLLRESQTSLLVSPLEQLLQGVSAQSRKADHITNIARYLYHSSSNPDAAFQSAKILRRITRYPNIQARLVGDFTHDQAVSERLMAGFVECLDSEEAQEGVTTNDSDSDSEKRVARIRHETKIHILNLLITSLELTGPNLGLYLLGYEVKKPVSSTNLQDPGVLGCPRSCLHAILSLLQRGSDSRSGPGLIKQAPQLAELCYQVIYQLCACPDTSGPTMRYLRTSQDFLFSHLQHLPFVLSENEIAALSQMSWLMKTTAIELRVTSLNRQRSHTQRLLNLLLDDQPHTLHTADGETGMEEENRSVSGFLQFGTVSKVRRRLLSVLDAIDFSQEAPELLQLDFFERTQIEQVITNCEHVNEQGHTVCNVKLLHRVLVAEINALQGMAAIGQRPLLMEEVNSVLQQVVERNRVRRSLSAKRHALQSWRSLVETILTACPSELIPADQRQLIIRDLLLDLHDKVLSEDAAGELMPIVAGAVFTLTAHLSQSVLSEQQGVGPEGGSGSGFASIANSALHLILRKLLDFILCTGGGFQRLRAHLYGALLYYLQIAQKPEEPETLQTGTSMWERLTAPEDCFSKLQRENLSIIESYGTALMEVVCRDACDGHEIGRMLALAVLDRVLSIDRQCQWLVYLCNSGYLRVLVESLKQDDVSLQTLLTPQPPLLKPLYIYESKMALLTRVAKTAQGAMELLRCGLVAQLVECQVFHMLPQNDALRVFGQRDPSGFIPSPLERYRQILLPTLRLMQVILTSTTAQHQQGAAQVLQWLIVHSDVIQSILHGQDMSMGSLQELSLLTAIISKTALPGALEMGQEINSAALMELQGHIGRFQRQSLSLLVRLVGTDRARYLKQIEDTVSPSNLAEKREEMEVAMQQICANIMEYCQTLLLQSSSEAQFSLCLFSPSASEPADVSIPSARVPSLGLVLLLLKNSASDFFRYHDSHRQSLNKLERVEQLPPEELKELCQGLVSGSGGVEKISSVQRNVLAKRRLVQLVNNRAKLLALCSYIIETCLFVIWRHLEFYLLYCTPTDPKDSLLPGYRDPAGSRGLSVSRVSQQDLEQLQSDMSSSFSEPLQRKLLEVEGLYSKSRSRHTFIQALTRRIRGLVHHAKS", "length": 1972, "header": "tr|A0AC58HT15-1|A0AC58HT15_DANRE Computationally mapped isoform of Nuclear pore complex protein Nup205 isoform X3 OS=Danio rerio OX=7955 GN=nup205 PE=1 SV=1 CANONICAL=A0A8M9PFD6-1" }, "locus": {} }, { "isoform_ac": "A0AC58HT19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6/entry#A0AC58HT19-1", "sequence": { "sequence": "MATQMAVNSGASLWGPLKELWEAVEGAIWRRQPESVHLLDLQLKKHKPYFLNLFKNPPKSAEQREKVRKASTEGIAIQGQQGARLLPEQLISEAFILSDLFDLGELAALELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCVANSLRSLIQSRHGKTFTLDLSPELVNLTTRFTDELMAQGLTKQILNLISDVSVTREFERLQKERGLGNEKHRKEVSDLIKECRQSLAECLFAWACQSPLGKDDTLALIGHLEMVTAEADGSLDSVNLALVMALLYSLDVSFLEQGTEDREDLLQALPLLTEKQYVAAVHSRLVEGQGWKLPGLQAAVQLAWALSLRALSQLPQGAALVEFTEADEALADQALLGGVFLFLTEGVLGSDGFSQEEFYTRRLHSLITDFLALMPMKVKQLRNRADEDARLIHMALQMGSEPPSSLRKDLDHLMILIGEFYSKDPFELELALEFWCPSESLQHTSLTGSFLGVPLQRPPHKQVVLSKFVRQMGDLLPATLYIPYLRMLKGLANGPQCSHYCFSLLKTNGAPHGENRQAGVSGSLVSWEHFFHSLMLYHENLRRDVPSADSTQYRHLPIRGITQRELEGLTAFLQLLTTIITWSENARLALCEHPQWTPVVVMLGLLQCSVQPVLKAQVLHVLAAFGKSPEIAASLWQSLEYTQILQTVKIPGQRQAAGIEVELNEIESSCEEYPLTRAFCHLISTLVESALPVNLGAGLRAPGFQPYLDFLRDSVFLAFPTRAYRRSAEKWEVAEAVLEVFHKLLREYEPQPSDFLPEMVELQGEQVPAHKPPGHSLMFHLLNDSPTLSLCLNLLEEGARQLDTYAQFPGKKQLESAVLHCLCLLELALQKEVTFMDLLRESQTSLLVSPLEQLLQGVSAQSRKADHITNIARYLYHSSSNPDAAFQSAKILRRITRYPNIQARLVGDFTHDQAVSERLMAGFVECLDSEEAQEGVTTNDSDSEKRVARIRHETKIHILNLLITSLELTGPNLGLYLLGYEVKKPVSSTNLQDPGVLGCPRSCLHAILSLLQRGSDSRSGPGLIKQAPQLAELCYQVIYQLCACPDTSGPTMRYLRTSQDFLFSHLQHLPFVLSENEIAALSQMSWLMKTTAIELRVTSLNRQRSHTQRLLNLLLDDQPHTLHTADGETGMEEENRSVSGFLQFGTVSKVRRRLLSVLDAIDFSQEAPELLQLDFFERTQIEQVITNCEHVNEQGHTVCNVKLLHRVLVAEINALQGMAAIGQRPLLMEEVNSVLQQVVERNRVRRSLSAKRHALQSWRSLVETILTACPSELIPADQRQLIIRDLLLDLHDKVLSEDAAGELMPIVAGAVFTLTAHLSQSVLSEQQGVGPEGGSGSGFASIANSALHLILRKLLDFILCTGGGFQRLRAHLYGALLYYLQIAQKPEEPETLQTGTSMWERLTAPEDCFSKLQRENLSIIESYGTALMEVVCRDACDGHEIGRMLALAVLDRVLSIDRQCQWLVYLCNSGYLRVLVESLKQDDVSLQTLLTPQPPLLKPLYIYESKMALLTRVAKTAQGAMELLRCGLVAQLVECQVFHMLPQNDALRVFGQRDPSGFIPSPLERYRQILLPTLRLMQVILTSTTAQHQQGAAQVLQWLIVHSDVIQSILHGQDMSMGSLQELSLLTAIISKTALPGALEMGQEINSAALMELQGHIGRFQRQSLSLLVRLVGTDRARYLKQIEDTVSPSNLAEKREEMEVAMQQICANIMEYCQTLLLQSSSEAQFSLCLFSPSASEPADVSIPSARVPSLGLVLLLLKNSASDFFRYHDSHRQSLNKLERVEQLPPEELKELCQGLVSGSGGVEKISSVQRNVLAKRRLVQLVNNRAKLLALCSYIIETCLFVIWRHLEFYLLYCTPTDPKDSLLPGYRGQLSLKLQDYFQMLLNDMVSYQIALCADPAGSRGLSVSRVSQQDLEQLQSDMSSSFSEPLQRKLLEVEGLYSKSRSRHTFIQALTRRIRGLVHHAKS", "length": 1997, "header": "tr|A0AC58HT19-1|A0AC58HT19_DANRE Computationally mapped isoform of Nuclear pore complex protein Nup205 isoform X2 OS=Danio rerio OX=7955 GN=nup205 PE=1 SV=1 CANONICAL=A0A8M9PFD6-1" }, "locus": {} }, { "isoform_ac": "F1QJ18-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6/entry#F1QJ18-1", "sequence": { "sequence": "MATQMAVNSGASLWGPLKELWEAVEGAIWRRQPESVHLLDLQLKKHKPYFLNLFKNPPKSAEQREKVRKASTEGIAIQGQQGARLLPEQLISEAFILSDLFDLGELAALELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCVANSLRSLIQSRHGKTFTLDLSPELVNLTTRFTDELMAQGLTKQILNLVSDVSVTREFERLQKERGLGNEKHRKEVSDLIKECRQSLAECLFAWACQSPLGKDDTLALIGHLEMVTAEADGSLDSVNLALVMALLYSLDVSFLEQGTEDREDLLQALPLLTEKQYVAAVHSRLVEGQGWKLPGLQAVVQLAWALSLRALSQLPQGAALVEFTEADEALADQALLGGVFLFLTEGVLGSDGFSQEEFYTRRLHSLITDFLALMPMKVKQLRNRADEDARLIHMALQMGSEPPSSLRKDLDHLMILIGEFYSKDPFELELALEFWCPSESLQHTSLTGSFLGVPLQRPPHKQVVLSKFVRQMGDLLPATLYIPYLRMLKGLANGPQCSHYCFSLLKTNGAPHGENRQAGVSGSLVSWEHFFHSLMLYHENLRRDVPSADSTQYRHLPIRGITQRELEGLTAFLQLLTTIITWSENARLALCEHPQWTPVVVMLGLLQCSVQPVLKAQVLHVLAAFGKSPEIAASLWQSLEYTQILQTVKIPGQRQAAGIEVELNEIESSCEEYPLTRAFCHLISTLVESALPVNLGAGLRAPGFQPYLDFLRDSVFLAFPTRAYRRSAEKWEVAEAVLEVFHKLLREYEPQPSDFLPEMVELQGEQVPAHKPPGHSLMFHLLNDSPTLSLCLNLLEEGARQLDTYAQFPGKKQLESAVLHCLCLLELALQKEVTFMDLLRESQTSLLVSPLEQLLQGVSAQSRKADHITNIARYLYHSSSNPDAAFQSAKILRRITRYPNIQARLVGDFTHDQAVSERLMAGFVECLDSEEAQEGVTTNDSDSEKRVARIRHETKIHILNLLITSLELTGPNLGLYLLGYEVKKPVSSTNLQDPGVLGCPRSCLHAILSLLQRGSDSRSGPGLIKQAPQLAELCYQVIYQLCACPDTSGPTMRYLRTSQDFLFSHLQHLPFVLSENEIAALSQMSWLMKTTAIELRVTSLNRQRSHTQRLLNLLLDDQPHTLHTADGETGMEEENRSVSGFLQFGTVSKVRRRLLSVLDAIDFSQEAPELLQLDFFERTQIEQVITNCEHVNEQGHTVCNVKLLHRVLVAEINALQGMAAIGQRPLLMEEVNSVLQQVVERNRVRRSLSAKRHALQSWRSLVETILTACPSELIPADQRQLIIRDLLLDLHDKVLSEDAAGELMPIVAGAVFTLTAHLSQSVLSEQQGVGPEGGSGSGFASIANSALHLILRKLLDFILCTGGGFQRLRAHLYGALLYYLQIAQKPEEPETLQTGTSMWERLTAPEDCFSKLQRENLSIIESYGTALMEVVCRDACDGHEIGRMLALAVLDRVLSIDRQCQWLVYLCNSGYLRVLVESLKQDDVSLQTLLTPQPPLLKPLYIYESKMALLTRVAKTAQGAMELLRCGLVAQLVECQVFHMLPQNDALRVFGQRDPSGFIPSPLERYRQILLPTLRLMQVILTSTTAQHQQGAAQVLQWLIVHSDVIQSILHGQDMSMGSLQELSLLTAIISKTALPGALEMGQEINSAALMELQGHIGRFQRQSLSLLVRLVGTDRARYLKQIEDTVSPSNLAEKREEMEVAMQQICANIMEYCQTLLLQSSSEAQFSLCLFSPSASEPADVSIPSARVPSLGLVLLLLKNSASDFFRYHDSHRQSLNKLERVEQLPPEELKELCQGLVSGSGGVEKISSVQRNVLAKRRLVQLVNNRAKLLALCSYIIETCLFVIWRHLEFYLLYCTPTDPKDSLLPGYRDPAGSRGLSVSRVSQQDLEQLQSDMSSSFSEPLQRKLLEVEGLYSKSRSRHTFIQALTRRIRGLVHHAKS", "length": 1970, "header": "tr|F1QJ18-1|F1QJ18_DANRE Computationally mapped isoform of Nuclear pore complex protein Nup205 OS=Danio rerio OX=7955 GN=nup205 PE=1 SV=3 CANONICAL=A0A8M9PFD6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification of 315 genes essential for early zebrafish development.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2004", "authors": "Amsterdam Adam, Nissen Robert M, Sun Zhaoxia, Swindell Eric C, Farrington Sarah, Hopkins Nancy", "evidence": [ { "database": "UniProtKB", "id": "F1QJ18", "url": "https://www.uniprot.org/uniprotkb/F1QJ18" } ], "reference": [ { "type": "PubMed", "id": "15256591", "url": "https://glygen.org/publication/PubMed/15256591" } ] } ], "pathway": [ { "id": "dre:445382", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:445382", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZJ67-1", "protein_name": "Nucleoporin 205", "gene_name": "Nup205", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARGAATALPWRRVFEGEAERRSPGRPGARSGSRSVPEVSFRCRQANFHQAASLWGPYKDIWQTVGNALWRRQPEAVHLLDMILKKHKPDFISLFKNPPKNVQQHEKIQKASSEGVAIQGQQGTRLLPEQLIKEAFIISDLFDIGELSAVELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCIANSLKTLIQSRRGKTWTLELSPELVSMTTRFTDELMEQGLTYKVLTLVSQIDVNNEFEKLQRDRGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSPLAKDDTLLLIGHLERVTVEANGSLDAVNLALLMALLYCFDTSFIEQSTEERDDMIHHLPLLTERQYIATIHSRLQDSQPWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAIAELAIADNVFLFLSESVVLAENFYQEEFYIRRIHNLITDFLAFMPMKVKQLKNRADEDARMIHMSIQMGNEPPISLRRDLEHLMLLIGELYKKNPFHLELALEYWCPSEPLQTPTVMGSYLGVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSSHVENIQGAGGSPVSWEHFFHSLLLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAFLQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPALKAELLKTLAAFGKSPEIAASLWQSLEYTQILQTVRVPSQRQAIGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFPSNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQLEDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKKHLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVSPLEQLLQGINPRTKKADNVVNIARYLYHGNSNPELAFESAKILCCISCNSNIQIKMVGDFTHDQNVSQKLMAGFVECLDSEDTEEFVRVEEGSELEKKLAAIRHETRIHILNLLITSLERSPPNLALYLLGFELKKPISTTNLQDPGVLGCPRTCLHAILNILEKGTDGRSGPVAVQACPQLAELCYQVIYQLCACSDTSGPTMRYLRTSQDFLFSQLQHLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLLHLLLDDLPVKPYSDGEGGMEDENRSVSGFLHFDTATKVRRKILSILDSIDFSQEIPEPLQLDFFDRAQIEQVIANCEHKNLQGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEISTILQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQELIQAEDRQLIIRDILQDVHDKVLDDEAAQELMPVVAGAVFTLTAHLSQAVRTEQKQPLVSGPAEAHYAFMLDSSFTSAPAAESQPVGFASIGDSSLHIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDTLEAAKKTMWERLTAPEDVFSKLQRENMAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLLEDDRTLQSLLTPQPPLLKALYTYESKMAFLTRVAKLQQGSLELLRSGVIVRLAQCQVYDMRPEVDSHSMFGMRDPPIFIPTPVDRYRQILLPALQLCQVILTSSMSQHLQAAGQVLQFLVSHSDTIQAILRCQDVSAGSLQELALLTGIISKAALPGMLNELDVDVNEGSLMELQGHIARFQRQCLGLLSRFGGSDRLRQFKLQEDNVEGDRLSKKDEIELAMQQICANVMEYCHSFMQQNSPNLQNAVCLFTPSLSETVNRDGARQDTQVPVVPYWRLPGLGIIIYLLKQSASDFFSYYDSHRRSVNKLQNVEQLPPDEIKELCQSVMPAGIDKISTAQKCVLARRRLVKLINNRAKLLSLCSYIIETCLFILWRHLEYYLLHCTPMDSQDSLFASRTLLKSRRLQEPNLDFSRSGLAQVNQHDIDQLQSDAINAFGESLQKKLLDIEGLYSKVRSRYSFIQALVRRIRGLLRISRN", "length": 2049 }, "evidence": [ { "id": "RGD:1309413", "url": "https://alliancegenome.org/gene/RGD:1309413#orthology", "database": "AGR" }, { "id": "HGNC:18658", "url": "https://alliancegenome.org/gene/HGNC:18658#orthology", "database": "AGR" }, { "id": "FB:FBgn0031078", "url": "https://alliancegenome.org/gene/FB:FBgn0031078#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040715-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040715-8#orthology", "database": "AGR" }, { "id": "SGD:S000003576", "url": "https://alliancegenome.org/gene/SGD:S000003576#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P47054-1", "protein_name": "Nucleoporin NUP192", "gene_name": "NUP192", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKWSAIPFQTLYRSIESGEFDFDLFKEVLPDLQNLNLNTDKLKNNASRSQLEKGEIELSDGSTFKVNQEFIFEAISLSDELNLDEIVACELILSGDTTANNGKVQYFLRRQYILQIVSFIVNCFHEDTELYQELIKNGALVSNILSAFKFIHTQLSEIKQQINKAQILENYNALFQQNIKFRRDFLLREYDILSQILYGLVDKGAIMKNKDFILSLLHHVSELDSNDFFIIYYTPAFFHLFASLRVLPDADVKLLHSQFMKDLKDDSIYTKPVKVALIFIFFAYFIGWCKEDPKRRADTMDFKTDVDEPMTSAVELGAIEQILIFAADTSIVEQDKSMELFYDIRSLLERHIPRLIPKQLLDDEKIFSQTTNSTYNPASATDNMSGRGLWNPSYPGMMSTTGTARLNSMPNNVNEYSYTTIVLSDQTQEFFLSSFDDVLQTIITDCAFLLTKIKDAEEDSLLSGEDLTLDDISLKADLERFFLSIYFFYASRPEYSCTFWSDKESNAYGFIEWCSRCNDNLMRSCFYLMVSSLSFGPENALNVYHYFGENSSISWKNIAQCLSDYTKKISNFNSSLHKRQQFSESTHNDIDSTAVALEEGLNEEAVIFLSSLLTLVGSVTYQVDEDVKSSLSKVFSDVLFEFTKINTPLVGAAFKVISNLVPKLESSRTKFWSFLDSLIFKDSSLNYSSESYRNAFTNVLTKYSDVLGFLQLFHNLISIHSRENNSEYMVFGKLAFPTRLGQGYRKVGIWPYFDYIFNDILAHVDQIVDIRNKRAVQLPILKIIYTGLCSFDYSVILNSIPAAANLDALVDCENFFNYVQECPAIPIFNYIFTEKIYKSIFNVVDVGVDQLSIELEGGKNQAELLQLAVKIINKVLDYQETYVEELFPIVKKHGKTDYFLPKNYSLHGLRSFYDAIFFNIPLVAHLGLYVGVDDQILATNSLRILAKLSERSNGSVASLSKRNKLLTIFDSVDESARIKDAFITQLESSITDAGVLALKLELLDFLTSNLSNYSRTMTISHLLLGFQVSNVISLGPNLATFISSGTSLLDSLISVLEASLNSITKDNIDYAPMRLATAALEIILKLCRNPLTSGLLYSYLIKENFFERIMILDPQVTRFTTWNGSPFDNSTEEKCKNFIESESVGAFLSFLAYRNYWTQYLGLFIHKISFSGTKSEVLTYVNYLISNTMYSVRLFSFLDPLNYGNICEPKETLSIFTNVPLNLEQVTLNKYCSGNIYDFHKMENLMRLIKRVRAESLHSNSFSLTVSKEQFLKDADVECIKAKSHFTNIISRNKALELNLSVLHSWVQLVQIIVTDGKLEPSTRSNFILEVFGTIIPKISDYIEFNITFSEELVSLAVFLFDIYNRDRKLITDKGTVDGRLYQLFKTCIQGINSPLSSVALRSDFYILANHYLSRVLSDQVGSEKVLQDLRLGSKKLVEIIWNDVVYGEGTSRVTGILLLDSLIQLANRSKENFILDSLMKTTRLLLIIRSLKNTDALLNSTTEHINIDDLLYELTAFKATVFFLIRVAETRGGASALIENNLFRIIAELSFLKVDPDLGLDLMFDEVYVQNSKFLKVNVTLDNPLLVDKDANGVSLFELIVPIFQLISAVLVSMGSSNKAVVQTVKGLLNTYKRLVIGIFKRDLLREKEDKKNSSDPNNQSLNEMVKLIVMLCTLTGYQNND", "length": 1683 }, "evidence": [ { "id": "RGD:1309413", "url": "https://alliancegenome.org/gene/RGD:1309413#orthology", "database": "AGR" }, { "id": "HGNC:18658", "url": "https://alliancegenome.org/gene/HGNC:18658#orthology", "database": "AGR" }, { "id": "FB:FBgn0031078", "url": "https://alliancegenome.org/gene/FB:FBgn0031078#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040715-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040715-8#orthology", "database": "AGR" }, { "id": "SGD:S000003576", "url": "https://alliancegenome.org/gene/SGD:S000003576#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8IQV9-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "Nup205", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDGECLANEQMCVGRQITNATHASTAVIEDMWTPYKHLYNTFQTAVSNRSGFTSDLEQCLKKYKHNFSNLLRNPPRSEKSRNLLRNALNEGVPMQGHSRKTKMSQDLADEAVILSDMFDLDEGFAVELLCTAQRQQKHHPGLSRGLVAVLLYYDGRKAISCTLRDMFQVVSGVSWNTELPKEITGLVTNYAESLVDGSGILGRLLQLLEEMDVDKECAMLTTNRAFGSKKHQNQVLGLYEDIQQALAMALFNWSAQRGLPRHIAIRLMHQLANRKNHDAGGNMDDVTLIMLMALLYAYDTSMLLVTEEPNEHTTRLPIFSDREFAECFLEELYAQSSWQAPRLNAIIAYSFGLTLASLRHAPLQLQATAISIINRDEMLIDEALGAQVFVFFHSLLLEKDLVYSTQFFYRRVHLLITDFIDFMNSKVSELRGRADESSHTIISFLNEGLEPPPNLDSNFELLMLCVAKMHGDPRVTIRLCNEYWGPGDPNGSTAFKNTSRSVSLFKFISLASDLLPQTLFKAYLKMISGLTRTDFSARCAFNMLRVPQMATGGKYAVSWDHFFTTLGNYYTSMRNDFNTNIGMSGETIYRTRSTPKAITQREAEHLVAVMGIIQAVAEHDEVSRIMICDHPNWQTPQVLLGLVACATPLFLKAEILHTLAALAKSKETARVIWFHLEASQIIPTVPVSRSYAQCSLLEEMEQIESRSEQYNLTRGILQLLYTLMTTNLPKSLGAGQRTPAYEGYLKSMINSVLLKFYNRAYKVPSEKWQVGAQCLKLLYYLLATYRPSAMDFLETVDEPPYPGFHVMMQLQLKSEMLQLLLCIVEEVRERLDNYNRFQGKKLLEECSLYALLILEAALAKQNAFFEAHSAANCPILLSGLNRMLLDLNPRSRKPDHVLNIIKYVTYNSWLPRHALAAIKILASVTQLPNVSTQILSMYGQGSNEKLEIRQGFVECLEMEVCVGKHDDDLLDQLALNNHVPYLGFGDDLDNEREMSGEREYSTIESQLELQAGDGALESKPASIELQLKEAIIKLFEMNLSQQLPNFVYFLLGVDVLREFMANGRQHLAIEMQSSCVNSVVLLLEKYMDKQRHSDKYCEHTARIVERIYHLFHGLCANRRTAETILRYFRLTCSDFLLRHLRSLPFRQHREDHVLHAMGHLLNCVSIDVKLAAKHGQMTRFNQMCDILLIGNGMERSSHGLSMELGHSLISQPSSSFLAMDVLPAGGSISAVAHGAGSASLGAPNTGVKSLKPSLLQETSQGLHVTRLLDILVLEAGTLSQPQLEFFDGHLITQLLRDCEASAEAGANSRANLINVRKLYYILTDELYMVQSIIASGQRKAISTEIMLLLNHAVNINRVRTQRCATLAFMAAWGQLVQVLFSNMPDAVLPATQRRQHIIDIVEKVLIKVQPIQPIIEISVQVSETVLLLLANLRYCCYQAEDQSPEDLAAEDSLSNGNGNAIGNDSQVNALCLGQRAIGTGSDGGSGGGRDIGSGGNSSNLRFILKNLVQWIMISEVKSQKLRINLYSSLLNCLRIAKRLRTDEHLEYQETLISRQESARTYNKEQRRDDRLRLKAMAAEVIGTFGEKLIDTICHDAVTGHDVCRMLALACLDMISELQAVSTLCDFVASRGYLKHILESLDQSSTALCGILQPVPDHLRPLYVYESRMAFLTRMANSNVGARLLLTEQALGVLSNMKVYDQQPDLKSSELNRNEPQTFLPSIDDRFRSILLPALSLCDAIVNSLGPRNNSAAVQVLNFLFAHIDMVEAMLRSATPYMDLGHLQQVAVISNLFARASTHELTALEDSVQLDLRNRLGRVQQLMIVVFGRFCVSEPTIRRMLQQDEEQQTNPTDDSKRLRVKYFLDIAANVSLYCRNVVTSHSKDSMTSKYLLTTVINDVTLLTGKMSSKKLTTIMHTILNQLKGSIGYYLSQKSIADNLLQQRASLPNISFGPNGKQSYIELSQRYNEKRSELRQAVFIAEQNLYLLWIHLDFYLRNTIDYANENRNAINESNMDDDNDMSVLNASQEEIVQLKQLLISTFNETFCTQLINASEDYSIKCKGFNGSLLRRIKALVQFAPITANDVNSSFDS", "length": 2090 }, "evidence": [ { "id": "RGD:1309413", "url": "https://alliancegenome.org/gene/RGD:1309413#orthology", "database": "AGR" }, { "id": "HGNC:18658", "url": "https://alliancegenome.org/gene/HGNC:18658#orthology", "database": "AGR" }, { "id": "FB:FBgn0031078", "url": "https://alliancegenome.org/gene/FB:FBgn0031078#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040715-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040715-8#orthology", "database": "AGR" }, { "id": "SGD:S000003576", "url": "https://alliancegenome.org/gene/SGD:S000003576#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q92621-1", "protein_name": "Nuclear pore complex protein Nup205", "gene_name": "NUP205", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPLAVNSAASLWGPYKDIWHKVGNALWRRQPEAVHLLDKILKKHKPDFISLFKNPPKNVQQHEKVQKASTEGVAIQGQQGTRLLPEQLIKEAFILSDLFDIGELAAVELLLAGEHQQPHFPGLTRGLVAVLLYWDGKRCIANSLKALIQSRRGKTWTLELSPELASMTTRFTDELMEQGLTYKVLTLVSQIDVNNEFEKLQRERGLGSEKHRKEVSDLIKECRQSLAESLFAWACQSPLGKEDTLLLIGHLERVTVEANGSLDAVNLALLMALLYCFDISFIEQSTEERDDMIHQLPLLTEKQYIATIHSRLQDSQLWKLPGLQATVRLAWALALRGISQLPDVTALAEFTEADEAMAELAIADNVFLFLMESVVVSEYFYQEEFYIRRVHNLITDFLALMPMKVKQLRNRADEDARMIHMSMQMGNEPPISLRRDLEHLMLLIGELYKKNPFHLELALEYWCPTEPLQTPTIMGSYLGVAHQRPPQRQVVLSKFVRQMGDLLPPTIYIPYLKMLQGLANGPQCAHYCFSLLKVNGSSHVENIQGAGGSPVSWEHFFHSLMLYHEHLRKDLPSADSVQYRHLPSRGITQKEQDGLIAFLQLTSTIITWSENARLALCEHPQWTPVVVILGLLQCSIPPVLKAELLKTLAAFGKSPEIAASLWQSLEYTQILQTVRIPSQRQAIGIEVELNEIESRCEEYPLTRAFCQLISTLVESSFPSNLGAGLRPPGFDPYLQFLRDSVFLRFRTRAYRRAAEKWEVAEVVLEVFYKLLRDYEPQLEDFVDQFVELQGEEIIAYKPPGFSLMYHLLNESPMLELALSLLEEGVKQLDTYAPFPGKKHLEKAVQHCLALLNLTLQKENLFMDLLRESQLALIVCPLEQLLQGINPRTKKADNVVNIARYLYHGNTNPELAFESAKILCCISCNSNIQIKLVGDFTHDQSISQKLMAGFVECLDCEDAEEFVRLEEGSELEKKLVAIRHETRIHILNLLITSLECNPPNLALYLLGFELKKPVSTTNLQDPGVLGCPRTCLHAILNILEKGTEGRTGPVAVRESPQLAELCYQVIYQLCACSDTSGPTMRYLRTSQDFLFSQLQYLPFSNKEYEISMLNQMSWLMKTASIELRVTSLNRQRSHTQRLLHLLLDDMPVKPYSDGEGGIEDENRSVSGFLHFDTATKVRRKILNILDSIDFSQEIPEPLQLDFFDRAQIEQVIANCEHKNLRGQTVCNVKLLHRVLVAEVNALQGMAAIGQRPLLMEEISTVLQYVVGRNKLLQCLHAKRHALESWRQLVEIILTACPQDLIQAEDRQLIIRDILQDVHDKILDDEAAQELMPVVAGAVFTLTAHLSQAVLTEQKETSVLGPAEAHYAFMLDSCFTSPPPEENPLVGFASIGDSSLYIILKKLLDFILKTGGGFQRVRTHLYGSLLYYLQIAQRPDEPDTLEAAKKTMWERLTAPEDVFSKLQRENIAIIESYGAALMEVVCRDACDGHEIGRMLALALLDRIVSVDKQQQWLLYLSNSGYLKVLVDSLVEDDRTLQSLLTPQPPLLKALYTYESKMAFLTRVAKIQQGALELLRSGVIVRLAQCQVYDMRPETDPQSMFGMRDPPMFIPTPVDRYRQILLPALQLCQVILTSSMAQHLQAAGQVLQFLISHSDTIQAILRCQDVSAGSLQELALLTGIISKAALPGILSELDVDVNEGSLMELQGHIGRFQRQCLGLLSRFGGSDRLRQFKFQDDNVEGDKVSKKDEIELAMQQICANVMEYCQSLMLQSSPTFQHAVCLFTPSLSETVNRDGPRQDTQAPVVPYWRLPGLGIIIYLLKQSANDFFSYYDSHRQSVSKLQNVEQLPPDEIKELCQSVMPAGVDKISTAQKYVLARRRLVKVINNRAKLLSLCSFIIETCLFILWRHLEYYLLHCMPTDSQDSLFASRTLFKSRRLQDSFASETNLDFRSGLAIVSQHDLDQLQADAINAFGESLQKKLLDIEGLYSKVRSRYSFIQALVRRIRGLLRISRN", "length": 2012 }, "evidence": [ { "id": "RGD:1309413", "url": "https://alliancegenome.org/gene/RGD:1309413#orthology", "database": "AGR" }, { "id": "HGNC:18658", "url": "https://alliancegenome.org/gene/HGNC:18658#orthology", "database": "AGR" }, { "id": "FB:FBgn0031078", "url": "https://alliancegenome.org/gene/FB:FBgn0031078#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040715-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040715-8#orthology", "database": "AGR" }, { "id": "SGD:S000003576", "url": "https://alliancegenome.org/gene/SGD:S000003576#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nuclear pore organization", "id": "GO:0006999", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006999", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFD6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "structural constituent of nuclear pore", "id": "GO:0017056", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017056", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFD6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nuclear pore inner ring", "id": "GO:0044611", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044611", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFD6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6" } ], "pmid": "" }, { "name": "nuclear pore", "id": "GO:0005643", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005643", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFD6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFD6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1166, "end_pos": 1168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1447, "end_pos": 1449, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 968, "end_pos": 970, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1166, "end_pos": 1168 }, { "start_pos": 1447, "end_pos": 1449 }, { "start_pos": 168, "end_pos": 170 }, { "start_pos": 812, "end_pos": 814 }, { "start_pos": 968, "end_pos": 970 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PFG6-1", "uniprot_ac": "A0A8M9PFG6", "uniprot_id": "A0A8M9PFG6_DANRE", "mass": { "chemical_mass": 49750.0, "monoisotopic_mass": 49750.0 }, "refseq": { "ac": "NP_001106809", "name": "uncharacterized protein LOC559426", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106809" }, "gene_names": [ { "name": "si:dkey-246g23.4", "type": "recommended", "evidence": [ { "id": "A0A8M9PFG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6" } ] }, { "name": "si:dkey-246g23.4", "type": "synonym", "evidence": [ { "id": "NP_001106809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106809" } ] } ], "protein_names": [ { "name": "Monocarboxylate transporter 13", "type": "recommended", "evidence": [ { "id": "A0A8M9PFG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6/entry#names_and_taxonomy" } ] }, { "name": "Solute carrier family 16 member 13", "type": "synonym", "evidence": [ { "id": "A0A8M9PFG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC559426", "type": "synonym", "evidence": [ { "id": "NP_001106809", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106809" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588728.8891041.1, SRR32588719.4530501.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505393, SAMEA4476811 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On or before Jul 31, 2025 this sequence version replaced XP_021323339.1, NP_001106809.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001106809", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106809" } ] }, { "annotation": "Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6#function" }, { "database": "UniProtKB", "id": "ARBA00059080", "url": "https://www.uniprot.org/uniprotkb/ARBA00059080#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-246g23.4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050419-234", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-234", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000013775", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000013775", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "559426", "url": "https://www.ncbi.nlm.nih.gov/gene/559426", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011701", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011701", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020846", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020846", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:559426", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559426", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YHATTCI", "url": "https://omabrowser.org/oma/group/YHATTCI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PFG6", "url": "https://www.orthodb.org/?gene=A0A8M9PFG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1QHU5", "url": "https://www.orthodb.org/?gene=F1QHU5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11360:SF255", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11360:SF255", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001106809", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001106809", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PFG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QHU5", "url": "https://www.uniprot.org/uniprotkb/F1QHU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QHU5-1", "url": "https://www.uniprot.org/uniprotkb/F1QHU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050419-234", "url": "https://zfin.org/ZDB-GENE-050419-234", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MERKRGTAGPAGPPLDGGYGWFIVLSTFLVFGLTFGVIKSFGVFFVEIHHYFSTTATASSWITSISVATVHIGAPVGSALSTYFGHRPVVMAGGLLSSVGMVLGSFAQDLLQLYITVGFLTGFGYALTWTPTVTMLGWYFDKRRPVANALSSTGECLLTFILTPSFQLMVDQFSWRGAMLILGALQLNLCVCGALLRPLSRHDYFKDSIEENEHELSKCSNNRADSDPMKVKVIRYVDYTLIANSRFMVYSMFGIFAALGFFAPSLFLVPYARSQGVEEYQAASLMSISAVLDLLGRVFFGWVANLRLVETVHQLIGTVVLLGAVLLLCPLATTFTQLAVFSAGYGLVFGATVAIHITVLAEVVGVERLGSALGFFMLIRSSGGLLGPPLAGIFIDKMSDYGAGFLMAGVALLVSALFLIVLHFMNKKETEHKKDICSENEEEHEDLKNRNFVFGKS", "length": 457, "header": "tr|A0A8M9PFG6-1|A0A8M9PFG6_DANRE Isoform 1 of Monocarboxylate transporter 13 OS=Danio rerio OX=7955 GN=si:dkey-246g23.4 PE=3 SV=1 CANONICAL=A0A8M9PFG6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PFG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6/entry#A0A8M9PFG6-1", "sequence": { "sequence": "MERKRGTAGPAGPPLDGGYGWFIVLSTFLVFGLTFGVIKSFGVFFVEIHHYFSTTATASSWITSISVATVHIGAPVGSALSTYFGHRPVVMAGGLLSSVGMVLGSFAQDLLQLYITVGFLTGFGYALTWTPTVTMLGWYFDKRRPVANALSSTGECLLTFILTPSFQLMVDQFSWRGAMLILGALQLNLCVCGALLRPLSRHDYFKDSIEENEHELSKCSNNRADSDPMKVKVIRYVDYTLIANSRFMVYSMFGIFAALGFFAPSLFLVPYARSQGVEEYQAASLMSISAVLDLLGRVFFGWVANLRLVETVHQLIGTVVLLGAVLLLCPLATTFTQLAVFSAGYGLVFGATVAIHITVLAEVVGVERLGSALGFFMLIRSSGGLLGPPLAGIFIDKMSDYGAGFLMAGVALLVSALFLIVLHFMNKKETEHKKDICSENEEEHEDLKNRNFVFGKS", "length": 457, "header": "tr|A0A8M9PFG6-1|A0A8M9PFG6_DANRE Isoform 1 of Monocarboxylate transporter 13 OS=Danio rerio OX=7955 GN=si:dkey-246g23.4 PE=3 SV=1 CANONICAL=A0A8M9PFG6-1" }, "locus": {} }, { "isoform_ac": "F1QHU5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6/entry#F1QHU5-1", "sequence": { "sequence": "MERKRGTAGPAGPPLDGGYGWFIVLSTFLVFGLTFGVIKSFGVFFVEIHHYFSTTATASSWITSISVATVHIGAPVGSALSTYFGHRPVVMAGGLLSSVGMVLGSFAQDLLQLYITVGFLTGFGYALTWTPTVTMLGWYFDKRRPVANALSSTGECLLTFILTPSFQLMVDQFSWRGAMLILGALQLNLCVCGALLRPLSRHDYFKDSIEENEHELSKCSNNRADSDPMKVKVIRYVDYTLIANSRFMVYSMFGIFAALGFFAPSLFLVPYARSQGVETVHQLIGTVVLLGAVLLLCPLATTFTQLAVFSAGYGLVFGATVAIHITVLAEVVGVERLGSALGFFMLIRSSGGLLGPPLAGIFIDKMSDYGAGFLMAGVALLVSALFLIVLHFMNKKETEHKKDICSENEEEHEDLKNRNFVFGKS", "length": 425, "header": "tr|F1QHU5-1|F1QHU5_DANRE Computationally mapped isoform of Uncharacterized protein LOC559426 OS=Danio rerio OX=7955 GN=si:dkey-246g23.4 PE=4 SV=1 CANONICAL=A0A8M9PFG6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2002", "authors": "Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA", "evidence": [ { "database": "UniProtKB", "id": "F1QHU5", "url": "https://www.uniprot.org/uniprotkb/F1QHU5" } ], "reference": [ { "type": "PubMed", "id": "12477932", "url": "https://glygen.org/publication/PubMed/12477932" } ] }, { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "F1QHU5", "url": "https://www.uniprot.org/uniprotkb/F1QHU5" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "F1QHU5", "url": "https://www.uniprot.org/uniprotkb/F1QHU5" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:559426", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559426", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4LFF4-1", "protein_name": "Tarag, isoform D", "gene_name": "Targ", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRNRRRSFPSSQYEDKTAAAQPSGSSLRSQSLSRLDISVQNSSIYYNDTRNTRPQMVSVAVGTVSTDILNGRTSFLSLSQSHGSEVDLPSFYESFNPTFLPKLPIRRFPHMLVGASNEPEISKNQPAIPPSRPIEPISEVPFVEPAFEKKYSRTRGFSKELSTHRDNENEYIESTDEVSQMLSFTSYTDEYDRAEPLITKTQKFYKKRSPLIPKYDSEDSYVVPKETDQQESGLSFNVTTVQLADTASPESFSEYDGNRTRKQSFDMESKNSKESFDFSRGGRRLGSGMVFIYMVIPPDGGFGWVIMVLSFLAQLIIDGLIFTIGVLLPSIAQDLDVSISSVSFVASVQIGCYFTSGAFSAVLINRFGFRKVAIAGVLCSAVSILASSWSVSLTMLIFFYSVLACAGGITLSMIWASSQLIVGYYFERYRPMANGFSCSGGGAGIVLFTFLNSWLVPIIGWRNMLRTQAGLIMLILLMVVAYVEVAPTQVGMYHLPGSSDTSSDEYYGNFYVHDYLRQSAMTAKSRSILSTYEPRPKKKGCAKFCPSCSNCCWRRRKKSQNADEQNLLIRPAPLEREDLFYTGPAEYEKPHSKENVDGKEFLLMGSDKNTQQVNYGIKNIRVDDEPDRISRVHRERRWSNENQKKQNSCRNSRFMLTVLKLFDYRLLKQFEFKILVASAFLFPMGFNIPFVYSSARTTIPVEYARMIGPIIGISNLVMRNILGILAYKRRSWTLGLCGCGLIFGGVSVLISAFYGENLIWFQFLYGFSYAVAPAVYSTLRGLIYVKYLGLSKLTNAFGITSLAMGMGAFIGTTIAGKLIGITGNYSAAFCFAGLCLIVSGFLKLLLPLLIKCRNRMAQ", "length": 859 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8I6ARJ5-1", "protein_name": "Monocarboxylate transporter 11", "gene_name": "Slc16a11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRGQRAGQGLQPGSSCVRSRRQVRGREPRGAERRGERRGAATRHPHSPQFPIQGWGLCVDNSIPVGLGVRSRPGLGGLAVSRSPALGTHPHPHPVSQVARAPVVISVYRRERSKLGSISALASCSAEPCLPGKRGENSAEPTLALSLPPTPGEVGPGSRAHAPGDVPTLGEQPEAGSQGRQLPSRGPGVETSFTGVSPPQQTAMTPKPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQDTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGDPLAPPRTPLAALGLGLFRRPAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDASARLVSGWLADQGWVPLPRLLVVFGSLTGLGVLAVGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFILSGSFIYMGLPRALPSCRPASPPATPPPERGELLPVPQVSLLSTGGSSSIRDTTC", "length": 650 }, "evidence": [ { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N837-1", "protein_name": "Monocarboxylate transporter 2", "gene_name": "slc16a7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPPSASTNLGYTPPDGGWGWAVVFGSFISIGFSYAFPKSLTIYFKEIQEYFSISYSQIAWVSSIMLATMYAGGPVSSILVNRYGSRPVVIAGGLMVGVAMVTASFGTSILHLYLCVGVIGGFGLAFNLQPALTIIGKYFLVKRPMANGIAMAGSPVFLSTLAPVNQFLFDQFGWRGSFFILGGVLFNCCVAGSLMRPIKIPVSKTTEDNISPQTAGQDESKPSGCSSKLNQFIDISLFKHRGFLIYLVGNVLMFFGFFAPVVFLAPYAKHQGVDEYSAAFLLSIFALVDMFARPGTGLVANTKWIRPKIQYFFSFAVTYNGLCHLMCPLLPGYIDLVVYAVLFGLAFGMVCALLFEVLMDLVGAQRFSSAVGLATIIECGPVLLGPPISGLLVDIFMDYKYMYFACGMMMLAGGVFLFIMNYYNYRWLKKEEKQRNAEELQIFSTKELAAIDEEIKLSIEEKLKD", "length": 465 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1QL69-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "slc16a13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEKPQKTEEEQRPCPQGAAPDGGWGWVVVGALFVISALVFGLIRSLGVFFVEFVQYFDESAQAVSWITSIGLAMQQLMSPIGAAASNVYGTRPVVMMGGFLSGLGFILASQATSLLHLYLTMGLISGLGWALVFTPTMASVMQYFTKRRSLAMGLGFTGVGLASFAFSPLFQYLVEAYAWRGALLILGGLSFNMVACGALIRPLGTPKVAVKTENSTKLNKCSFLLSRIYECFELSLLTHRGFVTYAVAITFFNAGYFIPYVHLVAHSRHIGFTEYQAAFVISITGVADIVGRVASGWASDLGKIRLLHMLVVWTGLLGLSLMLIPVAVVYAGLLLVSIVYGFCAGAMAPLAFAVVPEIVGIERVLGALGLLQLIESAGGLLGAPLSGWLKDSTGTYTVSFIAAGSFLMIGMLIAMTLPYFWSCTAPPAPSPSKKKSQEGSAEDGLIGESTSSNAINETLCSGDHIPYSDEEVKVCLSNDATHSVQEQEEIPQEMTHRSNFA", "length": 502 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BBA0-1", "protein_name": "Monocarboxylate transporter 4-like", "gene_name": "slc16a3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGVALDDGGCKVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIREFGVGYSDTAWISSILLAMLYGTGPLCSILVNRFGCRPVMLVGGLFASLGMILASFATSIIHIYLCTGVITGLGMALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYEYGWRGGFLILGGILLNCCACGALMRPLVPPKSSEAPGIENAPDDGDKTVKPKPKLLDFSVFRDRGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLSILGFIDIFARPTCGIIAGLQWVRPRCVYLFSFALIFNGITDLVGSLSKDYTSLVVFCIFFGISYGMVGALQFEVLMAVVGTEKFSSAIGLVLMLEAIAVLVGPPSAGRLLDHTKKYMFVFLLAGIEVVLSALVLAICNFLCIKKKPEAPDAAAVESGEPVEEKNHSSPPATEEPHTPNGNSEKPKTDLRPENVTEEPTEEETFLKEEDEKEKTITCSAESDL", "length": 501 }, "evidence": [ { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9P097-1", "protein_name": "Monocarboxylate transporter 9", "gene_name": "slc16a9a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAVKSESTLDGGWGWMIVVASFMAQFLSFGSPQSVGVLYPEWLSAFQEGKGMTAWVGSMVSGVALITSPVCSACVDNFGARPVTIFSGVMVAGGLMLSAFAPNISFLIFSYGIVVGMGCGLVYAATLTITCQYFDKRRGLALGIVTTGTSVGGFIYATLQNELIELFGLEGCLLIIGALALNLMACAGPMRPLNLPGYYLKQRAALQRTEDPEPLYSKPTAIIIESGSDLKTKPGLAENTTTVKLLINKDPTELQDSEGERKVHILSSSIIARAIKKWMRPYGQYFCETVELLQDRVFMAFCIAMFLFSLGAFPPVLFMEDVAQSEGLIDGIALIPLVSIVAMTTGIGKLILGVLADMRWVNSLYLYALTLIGSGTALLLIPVSKSYLGLQILSAAVGFFSGNWSLTSYITTKIVGIERLGQAHGILMCFGGFGIALGPPVVGWFFDWTQSYDLAFYLSGTCVLVSGVFLFLAALPCWNRTAQEGNSQAEEDVNTSQQHHSFDCDKVASVA", "length": 512 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QAK1-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "slc16a5b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTEGVEVHQPQPNTTVTRSRASSLQAFENADTASCKSEEPDQEEEEEQSSSTLPEERHCSTGGQANAQLAPDGGWGWVVVAATILVLAMTLAFPSCIGIFYTELQSDFQASNTETSWVPAIMMAVLHACGPICSVLVERCGCRATIIIGGILSGLGMAASSFAQTMVELYITAGIITGMGFSLCFQPSITMVGHYFVRRRAFANALSSTGTALGLSILPLLANYLLRNFGWRGSFLVLGGVLLNCCVCGAVMRPLAAKPKMETRTKETDNHHLKTNCLSVHQGLKGRLRATLSTIMTFLRRHMAFDLLCSNPYFCAYALGVSWMMLGFVVPLVYLVPYATAYGMEQDQAALLMAILGLINIIVRPATALVFGLPRFRGSHNFAYLFAIAVVINGLSNCVCGIGTSFLVLLVYVILFGFSMSLVGSLLFTVLMDTVEMSRFPSALGLISIMESIMLLLGPPLAGILVDSTGQYIYVFFACSVTGSTAGLFIMLSFYWLDRRRDREQVKSSSAHQDPHSLKPSLKMTIDCEYSPVPLHSKNTRDTETDV", "length": 547 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LFB5-1", "protein_name": "Solute carrier family 16, member 4", "gene_name": "Slc16a4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKREEKPSPYTKPLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFSAGPLAAIICDIFGEKTTSILGTFLVSGGYLISSWATGIPFLCVTMGLLPGLGSAFLYQVAAVVITKYFKKRLGLSTAIARSGMGLTFLLAPFTKLLIDLYDWTGALILFGAIALNLVPSSMLLRPVHIQSDSNSDIKNKGSILSATGPELSHKTETPNRNKAQESLIKDSAVKKSGQPTTTLTVLENQIEEISTRPHRNRPLLMSNDKTYKKKFVSWNCKEKLLDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGITETVSQLISGWIADQNWIKKYQYHKAYLILCGVTNLLAPLATTFPLLMAYTIFFAIFAGGYLALILPVLVDLSKNSRVHRFLGYASFFAGMAVLSGPPIAGSHVTYAGLKLTTLEDAGFELLILLCLSPKCWNYRHVPPFLASISFPIFFNEKE", "length": 504 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ACD6B5K3-1", "protein_name": "Monocarboxylate transporter 3 isoform X1", "gene_name": "slc16a8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGIVEDRETAGAPDGGWGWVVLLGGFVITGFSYAFPKAISVYFKELMHDFGCGYKDTAWISSIILAMLYGSGPISSIMVNKFGCRPVMLVGGLLASLGMISASFATSIIHLYITAGVITGLGLALNFQPSLIMLGAYFDKRRPLANGLAAAGSPVFLSALSPLGQLLLDQYGWRGGFLITGGLLLNCCTCGAVMRPLKLKERKACNQELKEMLPPEAGQENIVCENNNDKKPSKKKLLDFSVLRDKGLIIYIIAKFIVVLGLFVPTILLVNYAKDQGVPDKEAAFLLSIIGFIDIFARPTCGVVAGLKWVRPKMSYFFSLALLFNGLTDVCSATSTDYKGLIIFCVFFGLSYGMVGALQFEVLMGIVGTSKFSSALGLVLLFEAVAVLIGPPSAGYLVDKYKNYELIFYMAGGELITAGIFLALASFCCISQKKRKDSPQTQQTYVEVNPER", "length": 453 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1L1W9-1", "protein_name": "Monocarboxylate transporter 10", "gene_name": "slc16a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTEPEPTLEQEPTPEPEPTQEPTPEPTPEPEPTQEPESEPELELKQENGCTKASEQKSPEEFEPPEGGWGWVVMLASMWCNGSVFGIQNAFGIMFVYLLNEFGSEHDADLRFKTAWVGSLSMGMIFFCSPIVSVFTDLLGCRITAVGGAAVGCVGLLASSFVTSLGPMYFTYGIVFACGCSFAYQPSLVILGHYFKRRLGLVNGIVTAGSSVFTITLPYMLSGLLKSVGLYHTLRVLAIFMFILMLAGLTYKPLLPKPVSSSKPGSRCPPLSRIFNVNIWKSLGYRIWAFGIPAALYGYFVPYVHLMTHVEERFGPEANKEVLLACIGITSGVGRLIFGRVADYVPGVNKVFLQVSSFMVIGVMSMMIPLCHVFGGLIAVCLLMGLFDGCFICIMAPIAFELVGSQNVSQAIGFLLGMMSIPMTVGPPIAGFLRDRLGSYDVAFYLAGIPPLIGGAVLCAIPWVEARRKRREAANTAENTEKMLESRSPPLEDTVCRTEEPESVI", "length": 505 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A8JUR0-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "Dmel\\CG8028", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPQTGIVWLTIEHRLQSRPAYQMKKSKSYTLEAPDGGWGILVCIGMALPFTSALAALPSFGLVFGEFLKSIGAETSAMAIITSAFFSSMSFAGLFSGSLFQRFGMRQVGVTGGILYFLGTGMQLFATSTLHLIMAFSVVQGFAFGLMVPTCYTTFNHYFVKNRVMWMSFAQTLIGLGSMLYPIVMQKLMSWYGFRGCLLILTGLNAHAVFGMLVMHPVEWHMRRVPIQPEEQEELKELSPTVVIRVQPETPLKATREEPNFHTADPGARKLSHAEEQMLKVLSSRASSITSLGNWSGPVVVSDASPQMMHSLQTSRRPSTIAGASGAVAPAHATKKSWVRTIVDFLDLTLLKKPIFVNIVLGITFALYSDITFFTMQPVYLFELGYSRPDTATIIAIGAAADLASRIFLAITAVCIQVPSRYIYLAGAVFTVFARFAFNGITQFVGMACITAVIGFLRTWLHVPLPLVFADYLPKERFATGYGLFMFIQGNAMFLIGPIVGFIRDKTRDYIFVFHILNGFMILCAAPWVLEVLIVKFRRRNKIERNNVDHEDVDNQGRSAMVQ", "length": 563 }, "evidence": [ { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "B1AT66-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRASGQGPQRRRRGWATRDDSAVTFRDPQPRQPAGGARALRGPDPRGPARAHQAGPLLAGARRSQHMVGGAPPRPAETGCSRSRMTQKNSKLCARANVYTQVPDGGWGWAVAVSFFFVEVFTYGIIKSFGVFFNDLMDSFDESNSKISWIISICVFVLTFTAPLSTVLSNRFGHRLVVMAGGLLISLGMITASFSQRVYHMYISIGVISGLGYCFSFLPTVTILSQYFDKRRSVVTAVASTGECFAVFAFAPAITALKEHIGWRYSLLFVGLLQLNIMVCGALLRPIIIQGPGQSPKAVTLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKMEQETRAEQQQTLVTAPKHSQMKAPLLDFSVLKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDPDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTASLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPMLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMCLAAVCLALVRPCKKGLCQNSHSGENQTDRQRGKALQDIPEDFLEMDLGKCEHRAHMKMDPV", "length": 607 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A0E5-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "Slc16a14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYTSHEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMRPLSPEKVENCSGAEEPCALPAYSTESVKSGGPLDMTEEQDRRPGNEETVCDLQTQELQGQTHPRKNVCAFRVLKTVGQLTVRVQRGFRDWHSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDAFPLTSIIAILHIFGKVILGAVADLPCISVWNVFLIANFTLVLSIFLLPLMHTYASLAVICALIGFSSGYFSLMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGLLYMVGILFLLIQPCIQMTEQSGRKCMDSAHV", "length": 512 }, "evidence": [ { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A3B5-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "Slc16a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQALEQADGRWAWVVLLASLVTQALTVGFPSCIGVFFTDLQRDFQASNSETSWFPSIMGAMLHCGGPLCSILIKRFGCRVTMMLGGVLASLGMVASTFSDSLIHLFLTAGLITGLGMCFSFQSSITVVGLYFVRQRPLANALASIGISMGVTLWPLLARYLLETLGWRGAFLIFGGIFLHCCVCGAMLRPVATNVDPEPKEDLLLPPKTPTRSCLATCVSTIQYYLAFDILRHNMVFCIYVTGATWMTLGFSLPHIFLVPYAMHHGMEEYWAAMLMSIVGFCNIFLRPVAGMLAGRKSLAAYRKYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGTGILVFQVLMDIVPMDRFPSALGLFTILCGMGSLISPPLAGLLLDTTNNFNYVFYMSSGLLISASLFMGVGFYVAEKKLKQDRQAKMEDATSEITSKHSLTSEDKDSAKKQPYPENIYVTSV", "length": 466 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A734-1", "protein_name": "Monocarboxylate transporter 12", "gene_name": "Slc16a12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKITRVGSASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGLILGSFATSLKHLYLSLGVLTGLGFALCYSPAIAMVGKYFSRRKAFAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDPSGPEKSHDRDAQREDCKQASPYSPLTKEWTETRLCCSLQQGYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQSFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFAKIAKRMKRTQVPFLVKDSDPKLHLWTNGSVAYSIAKELDQKDEESLAKARTGCNLT", "length": 486 }, "evidence": [ { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F7B3-1", "protein_name": "Monocarboxylate transporter 1", "gene_name": "slc16a1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPAVGGPVGYTPPEGGWGWAVVLGAFISIGFSYAFPKSITVFFKEIEVIFNATSSQVSWISSIMLAVMYGGGPVSSILVNKYGSRPIMILGGCLSGAGLIAASFCNTVEGLYFCVGVVGGLGLAFNLNPALTMIGKYFYKKRPIANGIAMAGSPVFLSTLAPLNTWFFDQFGWRGSFLILGGLLLNCCVAGSLMRPIGPKPQPAVKADNSNSRAKERKTVVEVINGFIDLTLFKHRGFLLYLLGNVVMFFGLFSPLVFLSNYAKSKQIPREKAAFLLSILAFVDMVARPSMGIVANTKWVRPRVQHFFAASILLNGVCHLLAPLSTDYTGFVIYAIFFGFAFGWLSSVLFETLMDLVGAQRFSSAVGLVTIVECGPVLLGPPLLGKFNDIYHDYKYTYMGCGIVLLIGSLFLFVGMGINYKLLEREAKEESKKANQQDDPGKEVVEALKAAEDNAAEEAV", "length": 461 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FB53-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "slc16a5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPQQPSSMEEQSGELCEPESEELEKQGPGPPSNANAPDSYDAPDGGWGWVVLLATIIVLALTLAFPSCIIIFYLDLQKEFEATNSQTSWVPSIMTAVLHAGGPLCSVLVDRFGCRATVMFGGVLSGFGMAVSSFSHSIVDLYITAGVITGLGFCFSFQPAVTILGHYFVRRRPFANAMSSTGTALGLSTLPFLCDFLKIELGWRGSFLVLGAVLLNCCVCGAVMRPIRPRKPRKTNEINNSPKTSDKKGCMLGICQSLASSLRQQMAFDLFCSNTRFRVFSLGITWMMLGFVVPLIYLVPYASADDMDPSRAALLLSILGFVNIFVRPPVGVLFSLPWFKGRHIYVFSAALLINGLSNSICCISASFPVLLVYVLTYGLSMSVVGSLMFTVLMDTVEMSRFPSALGLLSIMESVTLLIGPPLAGFLVDRTQLYTYVFMACTIIVVLSALFLMFTFYWLDSRDAAKKDSPAKPAINISTDCQYSSVPIDGDKTNKPSSETENTTCV", "length": 506 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1Q7T3-1", "protein_name": "Monocarboxylate transporter 4 isoform X1", "gene_name": "slc16a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGGAVVDTGDSGVKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELIREFGVGYSDTAWISSILLAMLYGTGPLCSILVNRFGCRPVMMVGGLFASLGMVLASFATNIIHIYLCTGVITGLGLALNFQPSLIMLNRYFSEKRPLANGLAAAGSPVALCCLSPLGQVLQYKYGWRGGFLILGGLLLNCCACGALMRPLLAPKKTSEVEEKPKETKPKPKLLDFTVFKDRGFLIYTIAASIMVLGLFVPPVFVVSYAKELGNEDTKSALLLTILGFIDIFARPTSGIIAGLKWVRPRCVYLFSFAMIFNGIADILGSFAKDYASLVVFCIFFGISYGMVGALQFEVLMAIVGTEKFSSAIGLVLLVEAIAVLVGPPGAGRLLDATKNYMYVFMLAGCEVVLSALVLAICNLLFIKRKPQQPDPPAKMEMAITETEMEELNKAPKDDQDNGGGAENEKKQAIEPETKTTSKDEVKELESIEVDSIEVENASKKVSGPNGVAVEPESSL", "length": 508 }, "evidence": [ { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QW16-1", "protein_name": "Monocarboxylate transporter 5", "gene_name": "slc16a4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPKEQHSDGKTAKTPCSELKAKVMKKEKKKVVYREPPDGGWGWMVVLHCFLVNVLVMGTLKTFGIFFVALQDEFGGSSESISWIGSIMSSLRLSGGPLASVACAKLGNRVTSIVGALFVSAGFLFSIFATSVTYLYISMGLVVGLGFALLYQATSVVIVTYFRKRLATAYSIGRSGMGLTFALAPFTQLLLDQYAWQGALLILGGLMLNLVASGMLLRPINIRHPASPISNSTIHKTEKDPLKNNMNGNTPVANGTSKSDSSPPIHKDTLIIKNPVHEQNSLPHLDLKKPTQNGVNGTDSSQTKTSPEMNGVSPVDSLLENGRTENVPENSPKVLDFSLLKNPFFCIYTWSLVFSQLAYFIPYFHLSARARNLGIDPMDASFIISVAGITETVAQLASGWVTDRNLVHKYHYHKAYLILCGVVNLLSPLATSYILLMVYAVFFAIFCGGYMALLLPVLVDLVGADKLNNSMGFSMFFVGLGCLTGPPLAGFLYDYTQTYDCSFYLAGVCYLLSSISLFLEPLARRWQARKERLETLNQELMWSNGCFCPAPQRNGVV", "length": 558 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G5E8K6-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "Slc16a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARALEQADGRWAWVVLLSSLVTQALTLGFPTCIGVFFTDLQRDFQASNSETSWFPSILGAMVHGGGPLCSILVKHFGCRVTMMLGGVLASLGMVVSTFSGSLTHLFLTAGVITGLGMCFSFQSSITVVGLYFVRRRPLANALASMGLSMGVTLWPLLARYLLETLGWRGAFLIFGGILLHCCVCGALLRPVATNEVPEPKEDPLLPPKIPTRSCLATCVSTIRYHLAFDILRHNMGFCIYVTGVTWMNLGFALPHIFLVPYAMHHGVDDYWAAMLMSIVGFCNIFLRPMAGLLLAGRKSLAAYRKYLFAVAILINGLTNLICTVSADFRVLLGYCLVYSLSMCGVGILVFQVLMDIVPMDRFPSALGLFTILCGVTSLISPPLAGLLLDKTNNFSYVFYMSSGFLVSGSLILGVGFYAAEKKKLKQDGQAKMENATSEMTPMHDLTSEDKDSAKKQPYPESIYMTNV", "length": 468 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G8XYX6-1", "protein_name": "Monocarboxylate transporter 8", "gene_name": "slc16a2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHSESDDNTAGGTPGSEDPQAEESSSPAEEFEEQERKLAPEDSTVQLIHTGCTDKRPATPPGAHPGQGFVPPEGGFGWVVVFAATWCNGSIFGIQNSFGILHMMLVKHHEKQPDQASQFKVAWVGALAMGMIFFCSPVVSMFTDHFGCRKTAVCGAFVAFIGLLTSSFATTLGLWYFTYGILFGCGSSFAFQPSLVILGHYFRQRLGLANGVVTAGSSLFSMGLPVLLKKVVEPLGLPRTFQILSIFMLVQALLALAFKPLLPSGMCPMPGMALDGGPSTPESASRWQKGLAKIRRYFNVRVFSILTYRIWAFGVATAVLGYFVPYVHLLNFVKEQFGDTQREWLLLVCIGASSGVGRLLFGKIGDLIPGVKKIYMQVASFILLGVMSMMIPQCAVFEGLVVVFVLMGLCDGCFITIMAPIAFELVGPMQASQAIGYLLGLMAIPMTAGPPIAGLLHDHFGNYHVAFYLAGVPPIVGGIVMFFVPLVHQRMQKRRKETDDPSMDKMLKNCSNGDMLPGYTDMETHI", "length": 526 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0RCI4-1", "protein_name": "Monocarboxylate transporter 9", "gene_name": "Slc16a9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFQKSPDGGWGWVIVVVSFFTQFLCYGSPLAVGVLYVEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSLFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDSRRGLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGALALNILACGSLMRPLQTSDCPFPEKIAPENVPDRYSIYNEKEKNQEETMTFQDKGYSNEDKCLPNGDWGRETSLPKNPTGAAHTKEPEPYKKKVVEQTNFCKQLAKRKWQVYRNYCGETASLFKNKVFSALFVAILLFDIGGFPPSLLMEDVARSYHVREEDLTIPLISIFGIMTAVGKLLLGILADFKWVNTLYLYVATLIITGLALCAIPLAKSYVTLAILSGILGFLTGNWSIFPYVTTKTVGIDKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLLAILPCWGMCNQRLPKPAAPTTFFYKVASNV", "length": 508 }, "evidence": [ { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15374-1", "protein_name": "Probable monocarboxylate transporter 5", "gene_name": "SLC16A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKREGKVQPYTKTLDGGWGWMIVIHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFCAGPLVAIICDILGEKTTSILGAFVVTGGYLISSWATSIPFLCVTMGLLPGLGSAFLYQVAAVVTTKYFKKRLALSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALILFGAIALNLVPSSMLLRPIHIKSENNSGIKDKGSSLSAHGPEAHATETHCHETEESTIKDSTTQKAGLPSKNLTVSQNQSEEFYNGPNRNRLLLKSDEESDKVISWSCKQLFDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDIMDASYLVSVAGILETVSQIISGWVADQNWIKKYHYHKSYLILCGITNLLAPLATTFPLLMTYTICFAIFAGGYLALILPVLVDLCRNSTVNRFLGLASFFAGMAVLSGPPIAGWLYDYTQTYNGSFYFSGICYLLSSVSFFFVPLAERWKNSLT", "length": 487 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O15375-1", "protein_name": "Monocarboxylate transporter 6", "gene_name": "SLC16A5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPQALERADGSWAWVVLLATMVTQGLTLGFPTCIGIFFTELQWEFQASNSETSWFPSILTAVLHMAGPLCSILVGRFGCRVTVMLGGVLASLGMVASSFSHNLSQLYFTAGFITGLGMCFSFQSSITVLGFYFVRRRVLANALASMGVSLGITLWPLLSRYLLENLGWRGTFLVFGGIFLHCCICGAIIRPVATSVAPETKECPPPPPETPALGCLAACGRTIQRHLAFDILRHNTGYCVYILGVMWSVLGFPLPQVFLVPYAMWHSVDEQQAALLISIIGFSNIFLRPLAGLMAGRPAFASHRKYLFSLALLLNGLTNLVCAASGDFWVLVGYCLAYSVSMSGIGALIFQVLMDIVPMDQFPRALGLFTVLDGLAFLISPPLAGLLLDATNNFSYVFYMSSFFLISAALFMGGSFYALQKKEQGKQAVAADALERDLFLEAKDGPGKQRSPEIMCQSSRQPRPAGVNKHLWGCPASSRTSHEWLLWPKAVLQAKQTALGWNSPT", "length": 505 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O15403-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "SLC16A6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTQNKLKLCSKANVYTEVPDGGWGWAVAVSFFFVEVFTYGIIKTFGVFFNDLMDSFNESNSRISWIISICVFVLTFSAPLATVLSNRFGHRLVVMLGGLLVSTGMVAASFSQEVSHMYVAIGIISGLGYCFSFLPTVTILSQYFGKRRSIVTAVASTGECFAVFAFAPAIMALKERIGWRYSLLFVGLLQLNIVIFGALLRPIFIRGPASPKIVIQENRKEAQYMLENEKTRTSIDSIDSGVELTTSPKNVPTHTNLELEPKADMQQVLVKTSPRPSEKKAPLLDFSILKEKSFICYALFGLFATLGFFAPSLYIIPLGISLGIDQDRAAFLLSTMAIAEVFGRIGAGFVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMSCSIFFGFMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYIFIQSIAGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKMGLCQHHHSGETKVVSHRGKTLQDIPEDFLEMDLAKNEHRVHVQMEPV", "length": 523 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O15427-1", "protein_name": "Monocarboxylate transporter 4", "gene_name": "SLC16A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPEVAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV", "length": 465 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O35308-1", "protein_name": "Monocarboxylate transporter 3", "gene_name": "Slc16a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAGGPRRGAGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRELKRDFGAGYSDTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLVELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSMLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPPPGPPPRRDPSPHGGPARRRRLLDVAVCTDRAFVVYVVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPHVPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEIIFYLAGSEVALAGVFMAVTTYCCLRCSKNISSGRSAEGGASDPEDVEAERDSEPMPASTEEPGSLEALEVLSPRAGSPEQEPEEEAVPELDHESIGGHEARGQKA", "length": 492 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O35910-1", "protein_name": "Monocarboxylate transporter 4", "gene_name": "Slc16a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGAVVDEGPTGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYSDTAWISSILLAMLYGTGPLCSMCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQPSLIMLNRYFNKRRPMANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQASGGAEPHGPQRPSPRLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLKKVRPYSVYLFSFAMFFNGFTDLTGSTASDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATKVYKYVFILAGAEVLTSSLVLLLGNFFCIGKRKRPEVTKPEEVASEEEKLHKPPVDVRVDSREVEHFLKAEPEKNGEVVHTPETSV", "length": 471 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60669-1", "protein_name": "Monocarboxylate transporter 2", "gene_name": "SLC16A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPMPSAPPVHPPPDGGWGWIVVGAAFISIGFSYAFPKAVTVFFKEIQQIFHTTYSEIAWISSIMLAVMYAGGPVSSVLVNKYGSRPVVIAGGLLCCLGMVLASFSSSVVQLYLTMGFITGLGLAFNLQPALTIIGKYFYRKRPMANGLAMAGSPVFLSSLAPFNQYLFNTFGWKGSFLILGSLLLNACVAGSLMRPLGPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFSLFKHRGFLIYLSGNVIMFLGFFAPIIFLAPYAKDQGIDEYSAAFLLSVMAFVDMFARPSVGLIANSKYIRPRIQYFFSFAIMFNGVCHLLCPLAQDYTSLVLYAVFFGLGFGSVSSVLFETLMDLVGAPRFSSAVGLVTIVECGPVLLGPPLAGKLVDLTGEYKYMYMSCGAIVVAASVWLLIGNAINYRLLAKERKEENARQKTRESEPLSKSKHSEDVNVKVSNAQSVTSERETNI", "length": 478 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O70324-1", "protein_name": "Monocarboxylate transporter 8", "gene_name": "Slc16a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPDPEPVPVPPPEPQPEPEPQPLPDPAPLPELGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDKIKLAQTFQVLSTFMFVLTLLSLTYRPLLPSSQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQRDSSKDKMLSHDPDPNGELLPGSPTPEEPI", "length": 545 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O70451-1", "protein_name": "Monocarboxylate transporter 2", "gene_name": "Slc16a7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPSEPSAPLPQPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFKDIQEIFNTTSSQIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCIGMILASYSNSVIELYLTVGFIGGLGLAFNLQPALTIIGKYFYRRRPLANGCAMAGSPVFLSTLAPFNQYLFNNYGWKGSFLILGGIFLHSCVAGCLMRPVGPSPNTKKSKSKVGSRHDSTLKKASKVSTAQKVNRFLDFSLFMHRGFLIYLSGNVILFLGIFAPIIFLAQYAKHIGVDDYNSAFLLSVMAFIDMFARPSVGLIANTSLIRPRIQYLFSSAIIFTGICHLLCPLATTYSALVVYVVFFGLGFGSISSLLFECLMDIVGATRFSSAVGLTTIVECCPVLFGPPLAGKLLDITGEYKYLYIASGTVVLVSGTYLLIGNAINYRLLDKERKREKAKKKKSASHASREMEALNRSKQDEVTVKASNAHNPPSDRDKESNI", "length": 484 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O70461-1", "protein_name": "Monocarboxylate transporter 3", "gene_name": "Slc16a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAGGPRRGAGPPDGGWGWVVLGACFVITGFAYGFPKAVSVFFRELKRDFGAGYSDTAWVSSIMLAMLYGTGPLSSILVTRFGCRPVMLAGGLLASAGMILASFASRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSTLSPLGQLLGERFGWRGGFLLFGGLLLHCCACGAVMRPPPGPQPRPDPAPPGGRARHRQLLDLAVCTDRTFMVYMVTKFLMALGLFVPAILLVNYAKDAGVPDAEAAFLLSIVGFVDIVARPACGALAGLGRLRPHVPYLFSLALLANGLTDLISARARSYGTLVAFCIAFGLSYGMVGALQFEVLMATVGAPRFPSALGLVLLVEAVAVLIGPPSAGRLVDALKNYEIIFYLAGSEVVLAGVFMAVTTYCCQRCSKDIPPGPSAEGGTSDTEDVEAERDSEPMPASTEEPGSLEALEVLSPRAGSPEPEEEAVPDLSHESVGGHEAHGQNA", "length": 490 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95907-1", "protein_name": "Monocarboxylate transporter 3", "gene_name": "SLC16A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAGGPRRGEGPPDGGWGWVVLGACFVVTGFAYGFPKAVSVFFRALMRDFDAGYSDTAWVSSIMLAMLYGTGPVSSILVTRFGCRPVMLAGGLLASAGMILASFATRLLELYLTAGVLTGLGLALNFQPSLIMLGLYFERRRPLANGLAAAGSPVFLSALSPLGQQLLERFGWRGGFLLLGGLLLHCCACGAVMRPPPGPGPRPRRDSAGDRAGDAPGEAEADGAGLQLREASPRVRPRRRLLDLAVCTDRAFAVYAVTKFLMALGLFVPAILLVNYAKDAGVPDTDAAFLLSIVGFVDIVARPACGALAGLARLRPHVPYLFSLALLANGLTDLSSARARSYGALVAFCVAFGLSYGMVGALQFEVLMAAVGAPRFPSALGLVLLVEAAAVLIGPPSAGRLVDVLKNYEIIFYLAGSEVALAGVFMAVATNCCLRCAKAAPSGPGTEGGASDTEDAEAEGDSEPLPVVAEEPGNLEALEVLSARGEPTEPEIEARPRLAAESV", "length": 504 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P36021-1", "protein_name": "Monocarboxylate transporter 8", "gene_name": "SLC16A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALQSQASEEAKGPWQEADQEQQEPVGSPEPESEPEPEPEPEPVPVPPPEPQPEPQPLPDPAPLPELEFESERVHEPEPTPTVETRGTARGFQPPEGGFGWVVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATAGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIRMLGDKIKLAQTFQVLSTFMFVLMLLSLTYRPLLPSSQDTPSKRGVRTLHQRFLAQLRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEEEFSEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGDYHVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQRDSSKDKMLAPDPDPNGELLPGSPNPEEPI", "length": 539 }, "evidence": [ { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P36032-1", "protein_name": "Probable transporter MCH2", "gene_name": "MCH2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSEERHEDHHRDVENKLNLNGKDDINGNTSISIEVPDGGYGWFILLAFILYNFSTWGANSGYAIYLAHYLENNTFAGGSKLDYASIGGLAFSCGLFFAPVITWLYHIFSIQFIIGLGILFQGAALLLAAFSVTLWEIYLTQGVLIGFGLAFIFIPSVTLIPLWFRNKRSLASGIGTAGSGLGGIVFNLGMQSILQKRGVKWALIAQCIICTSLSTIALMLTRTTHQGLRQHKRSYKFELLDYDVLSNFAVWLLFGFVSFAMLGYVVLLYSLSDFTVSLGYTSKQGSYVSCMVSVGSLLGRPIVGHIADKYGSLTVGMILHLVMAILCWAMWIPCKNLATAIAFGLLVGSIMGTIWPTIASIVTRIVGLQKLPGTFGSTWIFMAAFALVAPIIGLELRSTDTNGNDYYRTAIFVGFAYFGVSLCQWLLRGFIIARDEIAVREAYSADQNELHLNVKLSHMSKCLFRYKQLPRRV", "length": 473 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050419-234", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-234#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53918-1", "protein_name": "Uncharacterized transporter ESBP6", "gene_name": "ESBP6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSTHSNDYFSASSGMVSETSSEVSSINSSQPVSFSKASIAAPVPCSDLHSTKSNDASRKLSISRTLTNRLNDIKKAVDDDNLQTEENSADVNKILESRFDVADAIRLQHNESVQSKLNIPVTHTTTAGASLSAPSSSAFSASSIQNDTTEHKASMDSKLMRNRLYPASTKHSGKDLEAQGITEFEPDEPTVKKVFTNKSTGQLELPPDGGYGWVVTFCVFLTMFSTWGCNASFGVDLAYYLNHDTYPGASKYDYALIAGLTVFLGQLLSPLVMALMRIIGLRTTMLFGDAVMLAAYLLASFTTKLWQLYVTQGFMVGCSISLIFVPATTVLPGWFLKKRAVAMGVSLLGTGAGGVVYGLATNKMLSDFGNTRWCLRIIGISCSISVLVAIALLKERNPTPAIGLKSPRAMFEQLKAMFSLKVITKPFVVLIALWFMFALFAYNMMVFTLSSYAISKGLSSHDASTLTAILNGSQSIGRPLMGLAGDKFGRANVTIVLTTLLTIYMFAFWIPAHTFVQLIFFSILVGSCVGVANVMNTVLIADMVKPEEFLPAWAFVNYCGAPFLLVCEVIAQALTVEKDKSNPYLHAQIFCGCCFIAALILISILREYSIRMKLTERQAMTNEKLKEWKASEYDTDSADEDWGKLKERKTKYDLLLGPGIKKYFLRMVYPMKV", "length": 673 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050419-234", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-234#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53985-1", "protein_name": "Monocarboxylate transporter 1", "gene_name": "SLC16A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPAVGGPVGYTPPDGGWGWAVVIGAFISIGFSYAFPKSITVFFKEIEGIFHATTSEVSWISSIMLAVMYGGGPISSILVNKYGSRIVMIVGGCLSGCGLIAASFCNTVQQLYVCIGVIGGLGLAFNLNPALTMIGKYFYKRRPLANGLAMAGSPVFLCTLAPLNQVFFGIFGWRGSFLILGGLLLNCCVAGALMRPIGPKPTKAGKDKSKASLEKAGKSGVKKDLHDANTDLIGRHPKQEKRSVFQTINQFLDLTLFTHRGFLLYLSGNVIMFFGLFAPLVFLSSYGKSQHYSSEKSAFLLSILAFVDMVARPSMGLVANTKPIRPRIQYFFAASVVANGVCHMLAPLSTTYVGFCVYAGFFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVVLIISGIYLFIGMGINYRLLAKEQKANEQKKESKEEETSIDVAGKPNEVTKAAESPDQKDTDGGPKEEESPV", "length": 500 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P53986-1", "protein_name": "Monocarboxylate transporter 1", "gene_name": "Slc16a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPAIGGPVGYTPPDGGWGWAVLVGAFISIGFSYAFPKSITVFFKEIEVIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYLCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFDIFDWRGSFLILGGLLLNCCVAGSLMRPIGPEQVKLEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTINKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSSYGKSKDFSSEKSAFLLSILAFVDMVARPSMGLAANTKWIRPRIQYFFAASVVANGVCHLLAPLSTTYVGFCVYAGVFGFAFGWLSSVLFETLMDLIGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGIYLFIGMGINYRLLAKEQKAEEKQKREGKEDEASTDVDEKPKETMKAAQSPQQHSSGDPTEEESPV", "length": 493 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P53987-1", "protein_name": "Monocarboxylate transporter 1", "gene_name": "Slc16a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPAIGGPVGYTPPDGGWGWAVVVGAFISIGFSYAFPKSITVFFKEIEIIFSATTSEVSWISSIMLAVMYAGGPISSILVNKYGSRPVMIAGGCLSGCGLIAASFCNTVQELYFCIGVIGGLGLAFNLNPALTMIGKYFYKKRPLANGLAMAGSPVFLSTLAPLNQAFFGIFGWRGSFLILGGLLLNCCVAGSLMRPIGPQQGKVEKLKSKESLQEAGKSDANTDLIGGSPKGEKLSVFQTVNKFLDLSLFTHRGFLLYLSGNVVMFFGLFTPLVFLSNYGKSKHFSSEKSAFLLSILAFVDMVARPSMGLAANTRWIRPRVQYFFAASVVANGVCHLLAPLSTTYVGFCIYAGVFGFAFGWLSSVLFETLMDLVGPQRFSSAVGLVTIVECCPVLLGPPLLGRLNDMYGDYKYTYWACGVILIIAGLYLFIGMGINYRLVAKEQKAEEKKRDGKEDETSTDVDEKPKKTMKETQSPAPLQNSSGDPAEEESPV", "length": 494 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P57787-1", "protein_name": "Monocarboxylate transporter 4", "gene_name": "Slc16a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGAVVDEGPTGIKAPDGGWGWAVLFGCFIITGFSYAFPKAVSVFFKELMHEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQIYLTTGVITGLGLALNFQPSLIMLNRYFNKRRPIANGLAAAGSPVFLCALSPLGQLLQDHYGWRGGFLILGGLLLNCCVCAALMRPLVAPQVGGGTEPRGPQRPPQRLLDLSVFRDRGFLIYAVAASIMVLGLFVPPVFVVSYAKDMGVPDTKAAFLLTILGFIDIFARPTAGFITGLKKVRPYSVYLFSFAMFFNGFTDLTGSTATDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTQKFSSAIGLVLLLEAVAVLIGPPSGGKLLDATKVYKYVFILAGAEVLTSSLVLLLGNFFCIGKRKRPEVTEPEEVASEEKLHKPPVDVGVDSREVEHFLKAEPEKNGEVVHTPETSV", "length": 470 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q08268-1", "protein_name": "Probable transporter MCH4", "gene_name": "MCH4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLNIPIIANSKRFLFSKDHEAQSTRDHDVELETREGPSSGYNPNFNAADAILKKNSDQVDLDVNKLTNVTSRVLNTPEASLIYDDDREFPDGGLKAWLVVFGAFMGLVPVFGLINSLGAIESYISKHQLANISSSTISWIFSLYLAISFLSCILSGGYFDRNGSIGLMCTGTVIYAGGLFALANCKSVWQFILAFSVCSGLGTGILMTPLIGTVATWFLKRRGIATSISTMGGSIGGIVFPIMLRKLYKEVGFQWAIRILSFICLTCLICASVLARERTKPVVQPFKSKAEVAKWYISSVFNWRYFLEGKFLFVAIGASFAESSLTSCATYLASYSMTRGNTENVAYTMITASNAVGILGRYIPGYFADKFIGRFNVEIITISMAALFNFVMWLPFGGNTKVLWAYVCLWGFSTGSILSLTPVCIGQISKTTDFGKRYATVYLLQALVTIPVLPIGGTLIGKGTVANYNHFIIFNSALMAAGAACYIISRHICVGAKLCKF", "length": 501 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q08777-1", "protein_name": "Riboflavin transporter MCH5", "gene_name": "MCH5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSDSLTPKDTIVPEEQTNQLRQPDLDEDSIHYDPEADDLESLETTASYASTSVSAKVYTKKEVNKGTDIESQPHWGENTSSTHDSDKEEDSNEEIESFPEGGFKAWVVTFGCFLGLIACFGLLNSTGVIESHLQDNQLSSESVSTIGWLFSLFLFVCSASCIISGTYFDRNGFRTIMIVGTVFHVAGLFATANSTKYWHFILSFAIVCGFGNGIVLSPLVSVPAHYFFKRRGTALAMATIGGSVGGVVFPIMLRSFFSMKSDTDPTYGFVWGIRTLGFLDLALLTLSIILVKERLPHVIENSKDGESRWRYILRVYILQCFDAKAFLDMKYLFCVLGTVFSELSINSALTYYGSYATSHGISANDAYTLIMIINVCGIPGRWVPGYLSDKFGRFNVAIATLLTLFIVMFVGWLPFGTNLTNMYVISALYGFCSGSVFSLLPVCCGQISKTEEFGKRYSTMYFVVGFGTLVGIPITGAIISIKTTADYQHYIIFCGLATFVSAVCYIISRAYCVGFKWVRF", "length": 521 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0E960-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "Dmel\\CG8389", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDVQSSRVVPDGGYGWIVVAAVALINMTNQSILSVFGQLFVGELQKMQEDTFTAALITNLNSLALNFSGLFIGPAIKSFKPRNVAATGCILVALGLALCAFASESWHFILGYSFFVGFGLGLISPSTFMAINSYFTTKRGRAVGVSLAGAGLGQVLIPHLVRYLLDNHGFRYAVLSMSSLSLFGLFGAAFLKPLNPPAKHNNRKHIRLLTEADGEKTSPLQVVIVPTNQSKIERSPPNVDTLCSRMGQRLVQAMDLELLKDLVFWSIIVGMALVYTATINFTMIFPGFLGQTAQLNSQMVAFCMSLVAGADIVFRLLLPIVTDHLRIPYRVVFLIGIVGLFVARCVLAENQTLPVIITMSVLTGMMKSATVINNNLTISAHCRSEKLAGGLGLSMMSKGVIVITVGQLLGWVRDYADSYLICLYAQGVILLVVVLVWTPEILYRHRRQRCATNKSMETQSIDAAEVAKLNS", "length": 471 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q3U9N9-1", "protein_name": "Monocarboxylate transporter 10", "gene_name": "Slc16a10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVPSQEEPAAERETNEAQPPGPAPSDDAPLPGPGPSDVSDVAAEKVEVELTRSAGSEPPVPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLDTFKAKDDDNMAFKTAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVVGAAVGFIGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLISSVKLFNTLRILCIFMFVLFLAGFTYRPLVPSTKEKESGGSRSSFFSRRKLSPPKKVFNFALFKETTYAVWAAGIPLALFGYFVPYVHLMNHVKERFQDVNNKEVLFMCIGITSGVGRLLFGRIADYLPGVKKVYLQVLSFFFIGLMSMMIPLCSAFGALIAVCLAMGLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPIAGLLHDKLGTYDVAFYLAGIPPFVGGVVLCLIPWIHSKKQRKISKNAGGEKMEKMLENQSSLLSGSSGIFKKDSASII", "length": 512 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q503M4-1", "protein_name": "Monocarboxylate transporter 12-B", "gene_name": "slc16a12b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQEKKKGGVLPPDGGWGWMIVAGCFVVTVCTRAVTRCISIFFVEFQMHFAKDYSGTAWIHSLVDCTTMLCAPLGSLIGNQLSCRIAVILGGFLASVGLVLSSFATSLEYLYATLGLLTGLGFALCYTPAIAMVGIYFCERKALAYGIAMSGSGIGTFILAPVVQLLIEHYSWRGALLILGGFVLNLCVCGALLRPIILKEEEACPLPVDSECGYSVKPPTLNGGPTRSAASDAKQRCFQSMQEYHFLLMPDFLVLAGSFLLLASGCSLPFVYLVPYALDVGVGHQHAAFLMSILGVIDIVGNITFGWLTDRRCLKKYRNICYMFAVGMEGLCCLFIPLLRTFVWLVPFSVLYGYFDGAYVALIPVVTSDVVGRQYLSSALGVVYFLHAVPYLVSPPIGGWLVDTTGTYTATFFLSGFALISSSLLLFSVAIIRYCQRNQKKNSLSKIPKLVSCEGKQVDYYPPKNKDLMLIIPATS", "length": 477 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5NC32-1", "protein_name": "Monocarboxylate transporter 11", "gene_name": "Slc16a11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTPKPAGPPDGGWGWVVAAAAFAVNGLSYGLLRSLGLALPDLAEHFERSAQDTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVFSAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQFLLDTFGWRGALLLLGAVTLHLTPCGALLRPLALSGDPLAPPRTPLAALGLGLFKRRAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALVVAVAAVGDACARLASGWLADQGWVPLPRLLVVFGSLTGLGVLAMGLVPTVGTEEGWGAPLLAAAGAYGLSAGSYAPLVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFLVCSSFILSGSFIYMGLPRALPSCRPASPPATPPPERGELLPVPQVSLLSAGGTGSIRDTTC", "length": 447 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63344-1", "protein_name": "Monocarboxylate transporter 2", "gene_name": "Slc16a7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSESSVKATAAPPPFPLPPDGGWGWVVVCASFISIGFSYAFPKAVTVFFNDIKDIFKTTSSQIAWISSIMLAVMYAGGPISSVLVNNYGSRPVVIVGGLLCCTGMILASFSSSVIELYLTVGFIGGLGLAFNLQPALTIIGKYFYRKRPLANGFAMAGSPVFLSTLAPFNQFLFNSYGWKGSFLILGAIFLHSCVAGCLMRPVGPSPRAAKSKSKVGSRQDSSTKRLSKVSTAEKINRFLDFGLFTHRGFLIYLSGNVVLFLGMFAPIIFLAPYAKDKGVDDYNSAFLLSVMAFTDMFARPSVGLIANTSLIRPRIQYLFSVAIMFTGICHLLCPLAHSYTALVVYVIFFGIGFGSISSLLFECLMDQVGASRFSSAVGLVTIVECCPVLFGPPLAGKLLDITGQYKYLYIASGIVVLSSGIYLLICNAINYRLLEKERKREKARRKKSASQASKEMEALSRSKQDDVTVKVSNTHNPPSDRDKESSI", "length": 489 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66HE2-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "Slc16a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVHRTEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTLACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLLNNYAWRGALLLVSALSLHLVACGALLRPLSLTEDTAVGGPWAQITSLLCHGPFLRYTVALTLINTGYFIPYVHLVAHLQDLGWDPLPAAFLLSVAAISDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVSLALFPVAQASTTLVVLAVAYGFTSGALTPVAFSVIPELVGTGRIYCGLGLVQMIESVGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLITLPHFFSCISLSTSRPQDLVIEAPDTKIPLPKEEGLGEN", "length": 428 }, "evidence": [ { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZSM3-1", "protein_name": "Monocarboxylate transporter 12", "gene_name": "SLC16A12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSGSHWTANSSKIITWLLEQPGKEEKRKTMAKVNRARSTSPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFTQDYAQTAWIHSIVDCVTMLCAPLGSVVSNHLSCQVGIMLGGLLASTGLILSSFATSLKHLYLTLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDHTTPEQNHVCRTQKEDIKRVSPYSSLTKEWAQTCLCCCLQQEYSFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHQQAAFLMSILGVIDIIGNITFGWLTDRRCLKNYQYVCYLFAVGMDGLCYLCLPMLQSLPLLVPFSCTFGYFDGAYVTLIPVVTTEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGRLVDTTGSYTAAFLLCGFSMIFSSVLLGFARLIKRMRKTQLQFIAKESDPKLQLWTNGSVAYSVARELDQKHGEPVATAVPGYSLT", "length": 516 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7RTX9-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "SLC16A14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYTSHEDIGYDFEDGPKDKKTLKPHPNIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVHYLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMLIQGAVSLNLCVCGALMRPLSPGKNPNDPGEKDVRGLPAHSTESVKSTGQQGRTEEKDGGLGNEETLCDLQAQECPDQAGHRKNMCALRILKTVSWLTMRVRKGFEDWYSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVNLYNLSEQNDVFPLTSIIAIVHIFGKVILGVIADLPCISVWNVFLLANFTLVLSIFILPLMHTYAGLAVICALIGFSSGYFSLMPVVTEDLVGIEHLANAYGIIICANGISALLGPPFAGWIYDITQKYDFSFYICGLLYMIGILFLLIQPCIRIIEQSRRKYMDGAHV", "length": 510 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7RTY0-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "SLC16A13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARRTEPPDGGWGWVVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPVGSALSTKFGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFAPTLACLSCYFSRRRSLATGLALTGVGLSSFTFAPFFQWLLSHYAWRGSLLLVSALSLHLVACGALLRPPSLAEDPAVGGPRAQLTSLLHHGPFLRYTVALTLINTGYFIPYLHLVAHLQDLDWDPLPAAFLLSVVAISDLVGRVVSGWLGDAVPGPVTRLLMLWTTLTGVSLALFPVAQAPTALVALAVAYGFTSGALAPLAFSVLPELIGTRRIYCGLGLLQMIESIGGLLGPPLSGYLRDVTGNYTASFVVAGAFLLSGSGILLTLPHFFCFSTTTSGPQDLVTEALDTKVPLPKEGLEED", "length": 426 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7RTY1-1", "protein_name": "Monocarboxylate transporter 9", "gene_name": "SLC16A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELKKSPDGGWGWVIVFVSFLTQFLCYGSPLAVGVLYIEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSLCVSSFGARPVTIFSGFMVAGGLMLSSFAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDDRRGLALGLISTGSSVGLFIYAALQRMLVEFYGLDGCLLIVGALALNILACGSLMRPLQSSDCPLPKKIAPEDLPDKYSIYNEKGKNLEENINILDKSYSSEEKCRITLANGDWKQDSLLHKNPTVTHTKEPETYKKKVAEQTYFCKQLAKRKWQLYKNYCGETVALFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSSNVKEEEFIMPLISIIGIMTAVGKLLLGILADFKWINTLYLYVATLIIMGLALCAIPFAKSYVTLALLSGILGFLTGNWSIFPYVTTKTVGIEKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLLAALPSWDTCNKQLPKPAPTTFLYKVASNV", "length": 509 }, "evidence": [ { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TM99-1", "protein_name": "Monocarboxylate transporter 9", "gene_name": "Slc16a9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFQKSPDGGWGWVIVVVSFFTQFLSYGSPLAVGVLYVEWLDAFGEGKGKTAWVGSLASGVGLLASPVCSLFVSSFGARPVTIFSGFLVAGGLMLSSLAPNIYFLFFSYGIVVGLGCGLLYTATVTITCQYFDSRRGLALGLISTGSSVGLFIYAALQRMLIEFYGLDGCLLIVGALALNILACGSLMRPLQTSDCPFPEKTAPENVPDRYSMYNEKEKNPEETMNFQDKGYSSEDKCLPNGDWGRETSLPKSLAIAAHTKEPETYKKKVVEQTNFCKQLAKRKWQLYRNYCGETASLFKNKVFSALFIAILLFDIGGFPPSLLMEDVARSYHVREEDLTMPLISIFGIMTAVGKLLLGILADFKWINTLYLYVATLIITGLALCAIPFAKSYVTLAILSGILGFLTGNWSIFPYVTTKTVGIDKLAHAYGILMFFAGLGNSLGPPIVGWFYDWTQTYDIAFYFSGFCVLLGGFILLLAILPCWDMCNKKLPKPAVPTTFFYKVASNV", "length": 508 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BGC3-1", "protein_name": "Monocarboxylate transporter 12", "gene_name": "Slc16a12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKITRVSLASPPDGGWGWMIVAGCFLVTICTRAVTRCISIFFVEFQTYFAQDYSQTAWIHSIVDCMTMLCAPLGSVVSNQLSCQAGIMLGGLLASTGFILGSFATSLKHLYLSLGVLTGLGFALCYSPAIAMVGKYFSRRKALAYGIAMSGSGIGTFILAPVVQLLIEQFSWRGALLILGGFVLNLCVCGALMRPITLKEDRSVPEKNHNRESQREDCKQASPYSPLTKECTETRLCCSLQQEYGFLLMSDFVVLAVSVLFMAYGCSPLFVYLVPYALSVGVSHHQAAFLMSILGVIDIVGNITFGWLTDRRCLKNYRYVCYLFAVALDGLCYLCLPMLQTFPLLVPFSCTFGYFDGAYVTLIPVVTAEIVGTTSLSSALGVVYFLHAVPYLVSPPIAGWLVDTTGSYTAAFLLCGFAMIFSSILLGFVRIVKRMKRTQVPFPVKDSDPKLQLWTNGSVAYSVARELDQKDEEPLPKARSGCNLT", "length": 486 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CE94-1", "protein_name": "Monocarboxylate transporter 13", "gene_name": "Slc16a13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRRAEPPDGGWGWMVVLSAFFQSALVFGVLRSFGVFFVEFVAAFEEQAARVSWIASIGIAVQQFGSPIGSALSTKLGPRPVVMTGGILAALGMLLASFATSLTHLYLSIGLLSGSGWALTFTPTMACLSRYFSQRRSLAMGLALTGVGISSFAFAPLFQWLINNYAWRGALLLVSALSLHLMACGALLRPLSLTEDAAVGGPGAQITSLLRHGPFLRYTAALTLINTGFFIPYVHLVAHLQDLGWDPLPAAFLLSVAAVSDLVGRVASGWLGDAVPGPVARLLMLWTTLTGVSLALFPVAQASSTLVVLAVAYGFTSGALTPVAFSVLPELVGTGRIYCGMGLVQMIESIGGLLGAPLSGYLRDVTGNYTASFVVAGAFLLAGSGVLLTLPHFFSCISVSTSRPQDLVIEASDTKIPLPKEEGLGEN", "length": 428 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K1C7-1", "protein_name": "Monocarboxylate transporter 14", "gene_name": "Slc16a14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYTSHEDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQSRGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVAAGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGALSLNLCVCGALMRPLSPEKLENCPEAEEPCALPAYSTESVKSGGPLGMAEEQDRRPGNEEMVCDLQTQECQGQTHPRKNVCAFRVLKTVSQLTVQVRRGFRDWHSGYFGTASLFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDTFPLTSIIAILHIFGKVILGAVADLPCISVWNVFLIANFTLVLSIFLLPLMHTYASLAVICALIGFSSGYFSLMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGLLYMVGILFLLIQPCIQMIDQSRRKCIEGAHV", "length": 512 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K1P8-1", "protein_name": "Monocarboxylate transporter 8", "gene_name": "SLC16A2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALPSPASEEAEGPCQEANQEYQEPVCSPVPEPEPEPEPEPEPEPEPVPVPPPEPQPEPEPQPLPDPAPLPVLGFEAEPVQEPEPTPTVETRGTARGFQPPEGGFGWIVVFAATWCNGSIFGIHNSVGILYSMLLEEEKEKNRQVEFQAAWVGALAMGMIFFCSPIVSIFTDRLGCRITATTGAAVAFIGLHTSSFTSSLSLRYFTYGILFGCGCSFAFQPSLVILGHYFQRRLGLANGVVSAGSSIFSMSFPFLIKMLGDRIKLAQTFQVLSTFMFVLTLLSLTYRPLLPSSQDTPSKRGAHTLRQRFLVQFRKYFNMRVFRQRTYRIWAFGIAAAALGYFVPYVHLMKYVEDKFKEIKETWVLLVCIGATSGLGRLVSGHISDSIPGLKKIYLQVLSFLLLGLMSMMIPLCRDFGGLIVVCLFLGLCDGFFITIMAPIAFELVGPMQASQAIGYLLGMMALPMIAGPPIAGLLRNCFGNYHVAFYFAGVPPIIGAVILFFVPLMHQRMFKKEQRESSKDKMLSHDPDPNGELLPGSPTPEEPI", "length": 545 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NCK7-1", "protein_name": "Monocarboxylate transporter 11", "gene_name": "SLC16A11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTPQPAGPPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPLVLPGDPPAPPRSPLAALGLSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFIYIGLPRALPSCGPASPPATPPPETGELLPAPQAVLLSPGGPGSTLDTTC", "length": 447 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R0M8-1", "protein_name": "Probable monocarboxylate transporter 5", "gene_name": "Slc16a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVKKEKTPSPYTKPLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFSAGPLAAIICDVLGEKATSILGTFLVSGGYVISSWATGIPFLCVTMGLLPGLGSAFLYQVAAVVITKYFKKRLGLSTAIARSGMGLTFLLAPFTKFLIDLYDWTGALILFGAIILNLVPSSMLLRPIHSQSNNNSDIENKGSILSATEPEASYKTETSKCKETQEPFIKDSTMKKSEQPTTTLTVLGNQSEEFSNRPHRNRPLLMSNGKSHKKKFVSWNCKQKLLDISLFRNPFFYIFTWSFLLSQLAYFIPTFHLVARAKTLGIDVMDASYLVSVAGITETVSQLISGWIADQNWIKKYQYHKSYLILCGVTNLLAPLATTFPLLMAYTILFAIFAGGYLALILPVLVDLSKNSRVHKFLGYASFFAGIAVLSGPPIAGWIYDYTQTYTGSFYFSGTCYILSSVSLFFVPLAERWKRKQSDLLRTTIK", "length": 500 }, "evidence": [ { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TF71-1", "protein_name": "Monocarboxylate transporter 10", "gene_name": "SLC16A10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLSQEEPDSARGTSEAQPLGPAPTGAAPPPGPGPSDSPEAAVEKVEVELAGPATAEPHEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNACGVLFVSMLETFGSKDDDKMVFKTAWVGSLSMGMIFFCCPIVSVFTDLFGCRKTAVVGAAVGFVGLMSSSFVSSIEPLYLTYGIIFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLRVLIDSVGLFYTLRVLCIFMFVLFLAGFTYRPLATSTKDKESGGSGSSLFSRKKFSPPKKIFNFAIFKVTAYAVWAVGIPLALFGYFVPYVHLMKHVNERFQDEKNKEVVLMCIGVTSGVGRLLFGRIADYVPGVKKVYLQVLSFFFIGLMSMMIPLCSIFGALIAVCLIMGLFDGCFISIMAPIAFELVGAQDVSQAIGFLLGFMSIPMTVGPPIAGLLRDKLGSYDVAFYLAGVPPLIGGAVLCFIPWIHSKKQREISKTTGKEKMEKMLENQNSLLSSSSGMFKKESDSII", "length": 515 }, "evidence": [ { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91Y77-1", "protein_name": "Monocarboxylate transporter 10", "gene_name": "Slc16a10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVPSQEEPAAAERETNEAQPPGPAPSDDAPLPVPGPSDVSDGSVEKVEVELTRSTGNQEPPEPPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSMLETFGAKDDDNMAFKAAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVLGAAVGFVGLMSSSFVSSIEPLYFTYGVVFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFTILLPLLLGNLTSTVGLCYTLRILCIFMFVLFLAGFTYRPLVPSSKEKESEDSRSSFFSRRKLSPPKKIFNFALFKETAYAVWAAGIPLALFGYFVPYVHLMNHVKERFKDVNNKEVLFMCIGVTSGVGRLLFGRIADYLPGVKKVYLQVLSFFFIGLTSMMIPLCSVFGALIALCLIMGLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPVAGLLHDKLGSYDLAFYLAGIPPFIGGAVLCLIPWIHSKKQREISKNTGGEKMEKMLANQSSLLSSSSGIFKKESDSII", "length": 514 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VQU7-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "GH25970", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVIQCTCDCNCSDSRDNRSVISCLLPGRSQPYKLGSSFGGDDMEQRIPYYRRLSNTSSALYGSCPQLLPSSSSTNNRHSWLRIPKNPQENPSENPSENPRQYSSLVRPKQRSPVLCNKCALXRRYNLSCEHPKQTAGHPGSGNTDQTAQTKPDKDSTNQRYLCYECRFNNQPLAWWVSCPRLSYLPAEQTKMQSTTTPTRHCHGGVGTQTTLPQTTSTPPTLPRFPSKRHCDNFGSYATLPTIEHQMTMPMMPHCSRHGGGGGGGVVGVGGLGGAVGSGMPSVMPAPPPPRYANPNINGCCYMYNPMPPAHQSHHQHDHHHAQQHHPVAQHQHHPHQYGPQYCLCDNWYHQPPPTQQQQHHHQQRAKNLMANGGCYFGYEANHHPSLHATTPHPSHITDEEDSAFPGLADREFHLLHRNIPALRRTGVDTTRIRQYFYPDGGWGWIICGVSFLVHILTTGLQLSYGLLWFYAVQYLHNTSGIELLGALSWSVSMVATSFVVSLCRKRSIRLLSIVGGLVMPLGILFTSFATEFGQVVFSYGIVFGVGVAMVREASTVMLGNYFKRRRQFVEMVAMSGEGVGIALFSVILKEGVGKAGWRLGLQIVAALTALSFFMGLMYRPASLYHPQRRAIQHLKNQRKKMREKKPILSQDVESTPKYFFLDISSLKSVTVKILLMTSSVASFGIYTPMFLMALNAAEQGSDVQELVLLQTFLGISMALGVVIAGALLRRCFVIRHFVINTKIVTQLFLSIVALAILFLSFVMGYTGLCILSWLYGIGLGGFQYSLKILALERIKLKHFSKAWGFIRGVESVPVLISVPLTSFLNDYSLKYGRAGYYICSAAAAISGIIIFFISEPQQQHQQQQQQLHHHYQQRNGHLATPTLMRHASARQHRPHLPMDYGYGEYPAPDLLSRSCISLNQMEPYLQANFCQRHMLQQQQQQQQQQQHSHLQQLACHNLDLQPHQGREAYQLGQGSIGAKMGKRLQRSLSFIQQHSNCCDGQMYCSWHSTYELGCHKSNKNPGSADRQPLICTCSSPNRNPVTYGTHGPTGPPGPTGPPGPPSSTRSRSVPEGLSTMSQQCNCRQGPATFAAPTREFIYVPHAYASLQRTPHRHSQGAGSGPGPGNSALRNNPQCRLKRSQSLCRPNAVQFVEQITTSV", "length": 1159 }, "evidence": [ { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VWJ0-1", "protein_name": "Major facilitator superfamily (MFS) profile domain-containing protein", "gene_name": "Yqy", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTDNGNNHNNNNNNNNDEALRLRLPEEQAEQLLPKNGSAGQTKIAPPTHTHSIAAASVPQKVPAKKKRDKSDLGEDFVAPDGGWGWLVSVASGVNILVTFALAQQFGILFRDRMAGLGISSSELTTIINTQIAVSAFTGLLNGPLFRRYTYRVVALVGSVLTFLGLFWMVFADTFAVYIMSFSILYGFGRGLTVSASSLAVNTYFKVKRRTATAFQFGVAGLGPIVCPYFATYMLYEFGVQGTTLLFAGASLHTIACSLIYQPVKWHVVKRDRDAEALQQVQPLAEREDQDEDIIKNVVEPETPVLPRANDGWFGSRASLNSVGTRNRLNTWEKSDSNGHVELKRLSSKDSNPGRQLRSISVSHSIKEEEATGYNSDHEVQHTELTEKEKQELEDEKERQRRKKLPFYMKVVIFFDMDLLRDITYVNLAVGITLINFVEINFAILTPFILSDLGFNKDQIALAMSTLGFFDLVVRFLIPLITAKINLSNRTFFVVGILGMCIGRMFLSMTSNFYVMMAIFLWLGLNKAFRTVFWSLIIPSYVPLKRLPAAAGLQLLMSGTFSMIFGPLIGLIRDHTSYAVTLNLLNALCVMAFAGWYLEDFIRARSRKSPPVKSIN", "length": 616 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VWJ1-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG8034", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASKQPRKVAPDGGWGWVACFGVSLVNLATRSIEPSFGLLFGDTLKELNVGTTGAAVIISALDVCMNFSGLFVGPLLKEFSYRKVAIAGSLLCGLGLALTSPATSMAHILSTYSVINGIGVGLSTSAAFVALNHYFKHKRGQAVGLSMAGTAMGMLIMPQLVRILLEAYDFRGAVLLLAGVALNATVGSVLLQPVKWHMKEEFDDEELMCISALPTPQPQLTVGGAGGAASAGAPVFKVIKEDGNEEDALPEMNTLLFHKPHPHQHSMRKNYSEMAMNTMNGSRLGIPKRPTFPRIMSLAGVQSAAHGAGGDSGGYTSQAEVNATQLRCRKASVTSNLSYMDFTGSILQVHLNTGDDEFEQNDRELRRVGTATGSIVLGGHRDSFIKMKPTELDKQAEAAAALDEEAKKKAKKPGFWRRFADLLDIDMLKDKMFLNLLFGLSIFYVAEMNFKMVTPFFFANLGYQKTDVAFCLSITAITDIAARIVLPPIFDRTTIKKRTIFLVSIIFVALTRSIMAEQTEWTQLMIWLSICGFFRGSALSNFTLTVSEYCSLEKLPSAFGWHLVGKALFVITFGPLIGLIRDVTDSYPICIHTQSVCIMICATAWGIEYLVEYIQSRRRTADAAQLPTQDVGATTTATSDQNDVKL", "length": 647 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VWK0-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG14196", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKKVYQDTTRPLPRVSRARYYNKHDKSDLGDDFVAPDAGWAWIVCVAAGVSNLSIYPCLQQFGFLFRERLSDLGMSSSQITAIINANPAVSACTGLLNGPMFRRFTFRQVAMAGSLLISGSLILTAFCETFLSYMVAYALLFGFGMGISVSASSLAINTYFQKKRRRAAGFSWTITGLGPIFLPHLVTFLLTIYGVQGTTLLFAAISLHSFVCALIYQPVRYHVKPPVEQLADQEQQAEALCAHCSWQQKREPGGIFSSQYLCQDDDAQRPGYEICEPGTPMLSRANDGWYGSRLSLTSGRLRFRTISSSKDLEQTQRLHCPISEEQNHESDEFLRPNNFRRERVESNLEAKLCCQCSAKREEHNNNRKEKEAEAEEAGMESAPLHDPQMSFLAKVVTFFDLDLLRDFTFVNLVAGLTIINFGELNFSILTPFILVDFGFDTPQITLAMSLLAGLDITMRFMVPFLTEKIPWDNRVFFLIGVVGIALGRTVVACTRSYSLILCSFVWIGLCKGVRTIFWPLIIPGYVPLNRLPGASGLQLLISGLFTLIGGPFVGLVRDRYDYSVTLHCLNMMSFVAATSWSLEALIRRHRRKQRLVNS", "length": 600 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" }, { "id": "SGD:S000005069", "url": "https://alliancegenome.org/gene/SGD:S000005069#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W0L6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG13907", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVDTNSSNPGIVGGNSASSARLRRFERTDSELACEEAARLTAEQSPEDEDNQDNDEDDDDEESVYGELPPPPDGGYGWVICFASFMCNMIVDGIAYTFGIFLEEFVAYFHEGKGTVAWVGSLLSGVYLSAGPIVSALANKYGCRAVCIAGSIIACIAFVLSTFSTNVSMLMATYGFMGGFGFGMIYLPAVVAVGYYFETKRSLATGIAVCGSGFGTFAFAPLATYLLEEYGWKNALLIFAGLILNCAIFGAMMRPLTYPKKKKQKPLMQRMYEEKQLQLERGSFAGSHFMVQLPDGTIERKLKMPLNADPGVHSSLNLELLAQQAGGGGLHPVSTLPTITESKVVDVHRQNGAQSPPNGDSNGQLSARSAAGAVGRRPHRNSESENSPYHSQDAMTRNASQPAFLAGDHQSLPKNGSVPAFNTRVRKTSASERFQPSLAAIRATSRGDLEAGAGGDFASSKLSLSQRQGGSQTGSSGRMVRPMSRKDIFYSGSVTNLPQYQSQKSLANYRNSVLSLTKYEKSMQSVAKLDPLAEAEKHREEYDLCPCLGIPDSVKSVVNTMLDVSLLKDPVFMLIGVSNIFGMAGLYVPFVYLVDAAKEHDIPKNDAAMLLSIIGITNTVGRVFCGWVADLPQVNSLLLNNCCLLVSTIAVTLTPLCYSYAAYITMSIFFGLAISGYISLTSIILVDLLGLDKLTNAFGLLILFRGFAALIGTPLAGAIYDMTHTYDLPFYMAGALFGISTITSFLAPCLKRCSPSEETPVHVETLTPIDEEQGEDAEDDEDQPITIVPKIIKTLASPQQEEGHPQFPQKTSESKL", "length": 816 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050419-234", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-234#orthology", "database": "AGR" }, { "id": "FB:FBgn0035173", "url": "https://alliancegenome.org/gene/FB:FBgn0035173#orthology", "database": "AGR" }, { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W509-1", "protein_name": "Monocarboxylate transporter 1, isoform B", "gene_name": "Mct1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVHGPPARRKSQQQHEACEMDMERQPTPPDGGWGWVVVFGSFMIHIVTDGMTYSFGIFYNEFLDYFNEGKGYTAWIASIMVGVTFSSGPISSSFVNRYGCRAVTIAGSILAASCIIVSMFAQNVLTLIITIGFGTGLGFGLIYLPAIVSVTQYFEAKRSLATGIAVCGSGFGTFVFAPLTEFLIGNYGWRGAMLIIGGIVLNCIIFGAMFRPLELEAPPQTPPNTPSTPKLAKKSAIIDQNTTAAELEPLKVLPKDQYLQLPQRTDTAVSGGALCRSNSVGHNLKPNLNNNSNGAVNGQGPTLVTPPQAVVKSTSNDDIARKCHSQLQLTPLRDAHRERSASGTMYRPDALYQGSLHNLPDYVSSRNDLSRSMSGSGVIKRYGSLRQSNNVSQSQEEAKCCGCITCSKETRDTFAEMMNFSLLKDMVFVIFSVSNFCTSIGFNVPYLYVVAYAETLKLTKTDASYLISTIGVANTVGRIILGYISDKPWVNRLLVYNVCLTACGVSTAMVPLCHDFQSLAFYCCVFGFTIGAYVGLTSVILVDLLGLDKLTNAFGLLLLFQGIASFIGPPIGGWMYDLTDSYAPAFLMAGLMIAISGLVMFAIPPLQRLQVRKSERKPHTEHLALS", "length": 626 }, "evidence": [ { "id": "SGD:S000001704", "url": "https://alliancegenome.org/gene/SGD:S000001704#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "symporter activity", "id": "GO:0015293", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015293", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6" } ], "pmid": "" }, { "name": "monocarboxylic acid transmembrane transporter activity", "id": "GO:0008028", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008028", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6" } ], "pmid": "" }, { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFG6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PFG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFG6" }, { "id": "PS50850", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50850" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Major facilitator superfamily (MFS) profile", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 427, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PFL7-1", "uniprot_ac": "A0A8M9PFL7", "uniprot_id": "A0A8M9PFL7_DANRE", "mass": { "chemical_mass": 29640.0, "monoisotopic_mass": 29640.0 }, "refseq": { "ac": "XP_021325693", "name": "uncharacterized protein si:ch211-210c8.6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325693" }, "gene_names": [ { "name": "si:ch211-210c8.6", "type": "recommended", "evidence": [ { "id": "A0A8M9PFL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFL7" } ] }, { "name": "si:ch211-210c8.6", "type": "synonym", "evidence": [ { "id": "XP_021325693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325693" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch211-210c8.6", "type": "synonym", "evidence": [ { "id": "A0A8M9PFL7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFL7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch211-210c8.6", "type": "synonym", "evidence": [ { "id": "XP_021325693", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325693" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021325693.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325693" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFL7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFL7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-210c8.6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFL7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-3630", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3630", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PFL7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PFL7", "database": "AlphaFoldDB", "categories": [] }, { "id": "564023", "url": "https://www.ncbi.nlm.nih.gov/gene/564023", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010721", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010721", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564023", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564023", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQMLWVW", "url": "https://omabrowser.org/oma/group/FQMLWVW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PFL7", "url": "https://www.orthodb.org/?gene=A0A8M9PFL7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32251", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32251", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32251:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32251:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325693", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325693", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PFL7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFL7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFL7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-3630", "url": "https://zfin.org/ZDB-GENE-030131-3630", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MIMGSTLAKCAATDLAIQWVGWALACSFKTEKFYDLAGSGTFILLAHLSRVWGGSGHLRQNVQTGLVTAWGLRLGTFLFLRILKEGQDRRFNNVRDSPGTFFVYWTMQALWVFVTLLPTLILNSERRDEPLGPRDYIGWGIWGLGFATEAIADQQKWNFKNDPDNVGKFIHHGLWAYSRHPNYLGEILQWSGLFLSASSIMQGPQYLSALSPLFVWFLLRHVSGIPILEKQAMKKWGSDPAFQNYVKNTPLLWPFPKVKGE", "length": 261, "header": "tr|A0A8M9PFL7-1|A0A8M9PFL7_DANRE Isoform 1 of Uncharacterized protein si:ch211-210c8.6 OS=Danio rerio OX=7955 GN=si:ch211-210c8.6 PE=1 SV=2 CANONICAL=A0A8M9PFL7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PFL7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFL7/entry#A0A8M9PFL7-1", "sequence": { "sequence": "MIMGSTLAKCAATDLAIQWVGWALACSFKTEKFYDLAGSGTFILLAHLSRVWGGSGHLRQNVQTGLVTAWGLRLGTFLFLRILKEGQDRRFNNVRDSPGTFFVYWTMQALWVFVTLLPTLILNSERRDEPLGPRDYIGWGIWGLGFATEAIADQQKWNFKNDPDNVGKFIHHGLWAYSRHPNYLGEILQWSGLFLSASSIMQGPQYLSALSPLFVWFLLRHVSGIPILEKQAMKKWGSDPAFQNYVKNTPLLWPFPKVKGE", "length": 261, "header": "tr|A0A8M9PFL7-1|A0A8M9PFL7_DANRE Isoform 1 of Uncharacterized protein si:ch211-210c8.6 OS=Danio rerio OX=7955 GN=si:ch211-210c8.6 PE=1 SV=2 CANONICAL=A0A8M9PFL7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:564023", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564023", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M9PET5-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG6282", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAVNVLDYDHFAISAIVVGSLQLVFFLINSVLQMDKLTDFAGGVNFIIISLLTFFLGQIDRPSKAYDSRQLMVTLFVCLWGARLSGYLLYRIVKLGRDKQFEDTRRNIIRYAVFWTFQAVWVYIVSLPVIIINSPRHSQPRAPKTMTTLDSTGTGMFIVGLLAETYADLQKFSFRQDPANQGKFCNDGLWSVSRHPNYFGEVVIWWGIFAISLNVISGHEWVAIASPIFTTMIILFLSGIPLRERSADEKYKDQLEYRKYKASTSPLIPVPPAVYVEVPSALKFILCCEFPIYDSMRIQKDLSPYSLSIARSHSHIXQSVAHSSSAAGVGQMNAHGHSVGHSLHRGQCYGANGGDAESHQNCGGSCRNVHVKSNPYQCEAGYGHYPVCHTDDDTDDGIIYMDRTHFYHDQEQAHVVKSVAVPSTKCSYLAEEELASDYDEDVPAIDLSKATSVESLGTRVQTEHAVNADGLPVTVTTIL", "length": 479 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-030131-3630", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3630#orthology", "database": "AGR" }, { "id": "FB:FBgn0035914", "url": "https://alliancegenome.org/gene/FB:FBgn0035914#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8LB65-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase FKBP17-3, chloroplastic", "gene_name": "FKBP17-3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLFTATVPSHHRFVSPSQHPKQSLLSQSLSVTFTENPQPTAVVTLQEQQLTDWITSPVTRRFGIGAGFTWAGFLAFGVVSEQMKKSRLDVFQEEDNTRGLEKQEEIILPNGIRYYDLQVGSGATPSSGYLVVFDVKGQVHGTEQVFVDTFGGKGKSLAMVMDSRPYSKGLCQGIEHVLRSMKAGGKRRVIIPPSLGFGDRNVEFGQGLEIPPSATLDYIIEVDTVYCFQTIV", "length": 234 }, "evidence": [ { "id": "A0A8M9PFL7", "url": "https://omabrowser.org/oma/group/A0A8M9PFL7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFL7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFL7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PFN2-1", "uniprot_ac": "A0A8M9PFN2", "uniprot_id": "A0A8M9PFN2_DANRE", "mass": { "chemical_mass": 43267.0, "monoisotopic_mass": 43267.0 }, "refseq": { "ac": "XP_017206555", "name": "solute carrier family 35 member F2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206555" }, "gene_names": [ { "name": "slc35f2l", "type": "recommended", "evidence": [ { "id": "A0A8M9PFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN2" } ] }, { "name": "slc35f2l", "type": "synonym", "evidence": [ { "id": "XP_017206555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206555" } ] } ], "protein_names": [ { "name": "Solute carrier family 35 member F2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PFN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN2/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 35 member F2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017206555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206555" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017206555.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017206555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206555" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "slc35f2l", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-1004", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-1004", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "559645", "url": "https://www.ncbi.nlm.nih.gov/gene/559645", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009262", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009262", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037185", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037185", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052221", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052221", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:559645", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559645", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PFN2", "url": "https://www.orthodb.org/?gene=A0A8M9PFN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14233", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14233", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14233:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14233:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06027", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06027", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017206555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017206555", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD05", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD05-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD05-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD17", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD17", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HD17-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HD17-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-1004", "url": "https://zfin.org/ZDB-GENE-130530-1004", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSPQRRRKMPREQLNTLCFKMREGLPKWRDVFTWQLLKILLMGQGLSALICGTAVTSQYLASVYYLNTPMLQSFINYTLLGITYTMALIFRRGDGNILQILKTKWWKYLLLAVADVEANYAVVKAYQYTTLTSIQLLDCFIIPVLMILSWFFLKTRYRIIHYAAVGICLAGVGAMVGADILAGQDQGSSSDVLLGDGLVLVSATLYAISNVCQEYTVKNLSRVEFLGMVGLFGSIISAIQLGILEHKEVANIQWTWEKALLLSGYALCMYGFYSFMPVVIKRSSATAVNLSLLTGDLFSLFFGLFLFHYNFSGLYIVSLVGILIGFIMFNTVPTLSRLSDPLSDEEGVDNHTADTDNNSIEGCEGEISCAHAEQRETPPACAVINSVKL", "length": 389, "header": "tr|A0A8M9PFN2-1|A0A8M9PFN2_DANRE Isoform 1 of Solute carrier family 35 member F2 isoform X1 OS=Danio rerio OX=7955 GN=slc35f2l PE=3 SV=1 CANONICAL=A0A8M9PFN2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PFN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN2/entry#A0A8M9PFN2-1", "sequence": { "sequence": "MSPQRRRKMPREQLNTLCFKMREGLPKWRDVFTWQLLKILLMGQGLSALICGTAVTSQYLASVYYLNTPMLQSFINYTLLGITYTMALIFRRGDGNILQILKTKWWKYLLLAVADVEANYAVVKAYQYTTLTSIQLLDCFIIPVLMILSWFFLKTRYRIIHYAAVGICLAGVGAMVGADILAGQDQGSSSDVLLGDGLVLVSATLYAISNVCQEYTVKNLSRVEFLGMVGLFGSIISAIQLGILEHKEVANIQWTWEKALLLSGYALCMYGFYSFMPVVIKRSSATAVNLSLLTGDLFSLFFGLFLFHYNFSGLYIVSLVGILIGFIMFNTVPTLSRLSDPLSDEEGVDNHTADTDNNSIEGCEGEISCAHAEQRETPPACAVINSVKL", "length": 389, "header": "tr|A0A8M9PFN2-1|A0A8M9PFN2_DANRE Isoform 1 of Solute carrier family 35 member F2 isoform X1 OS=Danio rerio OX=7955 GN=slc35f2l PE=3 SV=1 CANONICAL=A0A8M9PFN2-1" }, "locus": {} }, { "isoform_ac": "A0AC58HD05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN2/entry#A0AC58HD05-1", "sequence": { "sequence": "MSPQRRRKMPREQLNTLCFKMREGLPKWRDVFTWQLLKILLMGQGLSALICGTAVTSQYLASVYYLNTPMLQSFINYTLLGITYTMALIFRRGDGNILQILKTKWWKYLLLAVADVEANYAVLLDCFIIPVLMILSWFFLKTRYRIIHYAAVGICLAGVGAMVGADILAGQDQGSSSDVLLGDGLVLVSATLYAISNVCQEYTVKNLSRVEFLGMVGLFGSIISAIQLGILEHKEVANIQWTWEKALLLSGYALCMYGFYSFMPVVIKRSSATAVNLSLLTGDLFSLFFGLFLFHYNFSGLYIVSLVGILIGFIMFNTVPTLSRLSDPLSDEEGVDNHTADTDNNSIEGCEGEISCAHAEQRETPPACAVINSVKL", "length": 376, "header": "tr|A0AC58HD05-1|A0AC58HD05_DANRE Computationally mapped isoform of Solute carrier family 35 member F2 isoform X2 OS=Danio rerio OX=7955 GN=slc35f2l PE=3 SV=1 CANONICAL=A0A8M9PFN2-1" }, "locus": {} }, { "isoform_ac": "A0AC58HD17-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN2/entry#A0AC58HD17-1", "sequence": { "sequence": "MILSWFFLKTRYRIIHYAAVGICLAGVGAMVGADILAGQDQGSSSDVLLGDGLVLVSATLYAISNVCQEYTVKNLSRVEFLGMVGLFGSIISAIQLGILEHKEVANIQWTWEKALLLSGYALCMYGFYSFMPVVIKRSSATAVNLSLLTGDLFSLFFGLFLFHYNFSGLYIVSLVGILIGFIMFNTVPTLSRLSDPLSDEEGVDNHTADTDNNSIEGCEGEISCAHAEQRETPPACAVINSVKL", "length": 244, "header": "tr|A0AC58HD17-1|A0AC58HD17_DANRE Computationally mapped isoform of Solute carrier family 35 member F2 isoform X3 OS=Danio rerio OX=7955 GN=slc35f2l PE=3 SV=1 CANONICAL=A0A8M9PFN2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:559645", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559645", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JTZ7-1", "protein_name": "Solute carrier family 35, member F2", "gene_name": "Slc35f2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAESPASTRASEPRALGTVGSIGSQLSRIRGKLFTWDILKTIALGQMLSLCICGTAITSQYLAEKYRVNTPMLQSFINYCLLFLVYTVMLAFQSGSDNLLEILRRKWWKYTLLGLADVEANYLIVRAYQYTTLTSVQLLDCFGIPVLMALSWFILRARYKVIHFIAVFVCLLGVGTMVGADILAGREDNSGSDVLIGDILVLLGASLYAVSNVCEEYIVKKLSRQEFLGMVGLFGTIISGIQLLIVEYKDIARIQWDWKIALLFVAFALCMFCLYSFMPLVMKVTSATSVNLGILTADLYSLFFGLFLFEYKFSGLYILSFTVIMVGFILYCSTPTRTAEPAESSVPPVTSIGIDNLGLKLEESGLSETHSAVL", "length": 375 }, "evidence": [ { "id": "HGNC:23615", "url": "https://alliancegenome.org/gene/HGNC:23615#orthology", "database": "AGR" }, { "id": "MGI:1919272", "url": "https://alliancegenome.org/gene/MGI:1919272#orthology", "database": "AGR" }, { "id": "RGD:1311242", "url": "https://alliancegenome.org/gene/RGD:1311242#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-1004", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-1004#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TML3-1", "protein_name": "Queuine/queuosine transporter SLC35F2", "gene_name": "Slc35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAESPASAGASEPRALGTVDSIGSQLSRIRRKLFTWDILKTIALGQMLSLCICGTAITSQYLAEKYRVNTPMLQSFINYCLLFLVYTLMLAFQSGSDNLLEILRRKWWKYTLLGLADVEANYLIVRAYQYTTLTSVQLLDCFGIPVLMALSWFILRARYKVIHFIAVFVCLLGVGTMVGADILAGREDNSGSDVLIGDILVLLGASLYAVSNVCEEYIVKKLSRQEFLGMVGLFGTIISGIQLLIVEYKDIARIQWDWKIALLFVAFALCMFCLYSFMPLVIKVTSATSVNLGILTADLYSLFFGLFLFEYKFSGLYILSFTVIMVGFILYCSTPTRTVEPPESSVPPVTSIGIDNLGLKLEESGLPETHSAVL", "length": 375 }, "evidence": [ { "id": "HGNC:23615", "url": "https://alliancegenome.org/gene/HGNC:23615#orthology", "database": "AGR" }, { "id": "MGI:1919272", "url": "https://alliancegenome.org/gene/MGI:1919272#orthology", "database": "AGR" }, { "id": "RGD:1311242", "url": "https://alliancegenome.org/gene/RGD:1311242#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-1004", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-1004#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IXU6-1", "protein_name": "Queuine/queuosine transporter SLC35F2", "gene_name": "SLC35F2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEADSPAGPGAPEPLAEGAAAEFSSLLRRIKGKLFTWNILKTIALGQMLSLCICGTAITSQYLAERYKVNTPMLQSFINYCLLFLIYTVMLAFRSGSDNLLVILKRKWWKYILLGLADVEANYVIVRAYQYTTLTSVQLLDCFGIPVLMALSWFILHARYRVIHFIAVAVCLLGVGTMVGADILAGREDNSGSDVLIGDILVLLGASLYAISNVCEEYIVKKLSRQEFLGMVGLFGTIISGIQLLIVEYKDIASIHWDWKIALLFVAFALCMFCLYSFMPLVIKVTSATSVNLGILTADLYSLFVGLFLFGYKFSGLYILSFTVIMVGFILYCSTPTRTAEPAESSVPPVTSIGIDNLGLKLEENLQETHSAVL", "length": 374 }, "evidence": [ { "id": "HGNC:23615", "url": "https://alliancegenome.org/gene/HGNC:23615#orthology", "database": "AGR" }, { "id": "MGI:1919272", "url": "https://alliancegenome.org/gene/MGI:1919272#orthology", "database": "AGR" }, { "id": "RGD:1311242", "url": "https://alliancegenome.org/gene/RGD:1311242#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-1004", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-1004#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFN2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 219, "end_pos": 221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 289, "end_pos": 291, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 350, "end_pos": 352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 219, "end_pos": 221 }, { "start_pos": 289, "end_pos": 291 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 350, "end_pos": 352 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PFQ3-1", "uniprot_ac": "A0A8M9PFQ3", "uniprot_id": "A0A8M9PFQ3_DANRE", "mass": { "chemical_mass": 60930.0, "monoisotopic_mass": 60930.0 }, "refseq": { "ac": "XP_021323439", "name": "tripartite motif-containing protein 16", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323439" }, "gene_names": [ { "name": "trim110", "type": "recommended", "evidence": [ { "id": "A0A8M9PFQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3" } ] }, { "name": "trim110", "type": "synonym", "evidence": [ { "id": "XP_021323439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323439" } ] } ], "protein_names": [ { "name": "Tripartite motif-containing protein 16", "type": "synonym", "evidence": [ { "id": "A0A8M9PFQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3/entry#names_and_taxonomy" } ] }, { "name": "tripartite motif-containing protein 16", "type": "synonym", "evidence": [ { "id": "XP_021323439", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323439" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323439", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323439" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "trim110", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3", "locus": {} } ], "crossref": [ { "id": "A0A8M9PFQ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PFQ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd19802", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19802", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100536764", "url": "https://www.ncbi.nlm.nih.gov/gene/100536764", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100536764", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536764", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PFQ3", "url": "https://www.orthodb.org/?gene=A0A8M9PFQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF73", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF73", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323439", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323439", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLTLAVCVKTSCSTLHRRLQDTTAAMGSLEEQHTCPMCRDLFGRAQPFPCGHSFCPTCAQEAWSQNEGSGKRRFVCPRCLEEQGMVLCDCCPEEEGDEAQEAVKTCLNCEISLCEQHLLPHLQRPAYSTHLLVEPLMEVSRRRCPAHKEMFRYYCMDDGQYVCADCILEGQHAQHQVKGVRKVEEEYKVKLQSLFEKAEEKIKQGEMMLKEHQRASRTIIEDSSVSDVSQVLQMGSALQAQVGRLVSAVIKITEQERQKAMERVQEDCSRVKGDLNQTESIHHFLGSLLEESDPFLLIWAFQTEDSQMMSDLSSPLFTPAQPSMDKKRVLENVENKYREFIADTLRCLIELKRDLLSSPLTLDKNSAHPLLNISEDLRSVRRVPNRLPVPDHPDRFDHWSQVLSCQIFSSGTHYWELEVEGFWDIAVTYHCIGRKAKEGTAFGCNKISWSLTQQHDRKLSAWHNRKKTHLSAKMSGNHLAVALDYDSGSITFSEVGPSSTLLPLHNFSCSFTQPICLGFGLYKPELNSKVTILKKI", "length": 536, "header": "tr|A0A8M9PFQ3-1|A0A8M9PFQ3_DANRE Isoform 1 of Tripartite motif-containing protein 16 OS=Danio rerio OX=7955 GN=trim110 PE=4 SV=1 CANONICAL=A0A8M9PFQ3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PFQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3/entry#A0A8M9PFQ3-1", "sequence": { "sequence": "MLTLAVCVKTSCSTLHRRLQDTTAAMGSLEEQHTCPMCRDLFGRAQPFPCGHSFCPTCAQEAWSQNEGSGKRRFVCPRCLEEQGMVLCDCCPEEEGDEAQEAVKTCLNCEISLCEQHLLPHLQRPAYSTHLLVEPLMEVSRRRCPAHKEMFRYYCMDDGQYVCADCILEGQHAQHQVKGVRKVEEEYKVKLQSLFEKAEEKIKQGEMMLKEHQRASRTIIEDSSVSDVSQVLQMGSALQAQVGRLVSAVIKITEQERQKAMERVQEDCSRVKGDLNQTESIHHFLGSLLEESDPFLLIWAFQTEDSQMMSDLSSPLFTPAQPSMDKKRVLENVENKYREFIADTLRCLIELKRDLLSSPLTLDKNSAHPLLNISEDLRSVRRVPNRLPVPDHPDRFDHWSQVLSCQIFSSGTHYWELEVEGFWDIAVTYHCIGRKAKEGTAFGCNKISWSLTQQHDRKLSAWHNRKKTHLSAKMSGNHLAVALDYDSGSITFSEVGPSSTLLPLHNFSCSFTQPICLGFGLYKPELNSKVTILKKI", "length": 536, "header": "tr|A0A8M9PFQ3-1|A0A8M9PFQ3_DANRE Isoform 1 of Tripartite motif-containing protein 16 OS=Danio rerio OX=7955 GN=trim110 PE=4 SV=1 CANONICAL=A0A8M9PFQ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100536764", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536764", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFQ3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 506, "end_pos": 508, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PFQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 180, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PFQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 340, "end_pos": 536, "start_aa": "Phe", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PFQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ3" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 79, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 276, "end_pos": 278 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 506, "end_pos": 508 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PFQ4-1", "uniprot_ac": "A0A8M9PFQ4", "uniprot_id": "A0A8M9PFQ4_DANRE", "mass": { "chemical_mass": 92166.0, "monoisotopic_mass": 92166.0 }, "refseq": { "ac": "XP_021330042", "name": "TBC1 domain family member 12", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330042" }, "gene_names": [ { "name": "tbc1d12a", "type": "recommended", "evidence": [ { "id": "A0A8M9PFQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4" } ] }, { "name": "tbc1d12a", "type": "synonym", "evidence": [ { "id": "XP_021330042", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330042" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 12", "type": "synonym", "evidence": [ { "id": "XP_021330042", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330042" }, { "id": "A0A8M9PFQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021330042.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021330042", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330042" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tbc1d12a", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-3920", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3920", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "563626", "url": "https://www.ncbi.nlm.nih.gov/gene/563626", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050302", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050302", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:563626", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563626", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PFQ4", "url": "https://www.orthodb.org/?gene=A0A8M9PFQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47219:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47219:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021330042", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330042", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-3920", "url": "https://zfin.org/ZDB-GENE-030131-3920", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MERVEDAGEPKLAPFIDVNDNREEHKARVCGSDTDGAREGSVYISPYADPGGAGQQTLSSVLTGCKAGVLNGFPEQLDMVCPDGEEETQSDTGRVSGTFETEDKPDKAYLNSQMRSAVSFMGKTSPDMKIPNGDVTHEHMDHDQTQLRCLNYTEGFNRKASAALDRGVKVGNGGLLIVNSYDTLSQVPFGALGGLPAPERPVFVHQSDGVLSSGRSCERVSHPSADEAHLCDPDPVYTLTDLSTKLSLSPLAENTSDYTETDPSPEEDFSDTGPPVRPQNLRTNPGHPISLSCDATPLSPEDDGYFGAEGCVDECLSSGNTFEGVRRQSAPDRVDVDPNASSDQTLGTKRHGIADFLTRSLFSWKPKESRAVASHSAPGWKLFGKIQLRDNPLKDSRTIQQEYEFRAGPATGPPLHPPPTRRKNLEFEPLSTTALILEDRPANLPAKSEEESQRHRQEYSEMVAGAKRREMKEAQKKKRQMKERYRQEENIASAMVIWNSEVLPNWESMRNTRRVRDLWWQGVPPSVRGKVWCLAIGNELNITPELYEIFLSRAKEKWRSFSETSSVNENEDCGVSLADRESSLDLIKLDISRTFPSLYIFQKGGPYHDILHSVLGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQMAFFRVDHDLMLKYFAAFEVFFEENLPRLFQHFQNNSLTPDFYLIDWIFTLYSKSLPLDVACRVWDVFCRDGEEALFRTGLGILRLYQDVLLQMDFIHSAQFLSRLPENTPAHTLFSCIANTQMISNNRRWNQVFSTLIKDRLKETDKISNSSSNSNSPALRS", "length": 823, "header": "tr|A0A8M9PFQ4-1|A0A8M9PFQ4_DANRE Isoform 1 of TBC1 domain family member 12 OS=Danio rerio OX=7955 GN=tbc1d12a PE=4 SV=2 CANONICAL=A0A8M9PFQ4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PFQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4/entry#A0A8M9PFQ4-1", "sequence": { "sequence": "MERVEDAGEPKLAPFIDVNDNREEHKARVCGSDTDGAREGSVYISPYADPGGAGQQTLSSVLTGCKAGVLNGFPEQLDMVCPDGEEETQSDTGRVSGTFETEDKPDKAYLNSQMRSAVSFMGKTSPDMKIPNGDVTHEHMDHDQTQLRCLNYTEGFNRKASAALDRGVKVGNGGLLIVNSYDTLSQVPFGALGGLPAPERPVFVHQSDGVLSSGRSCERVSHPSADEAHLCDPDPVYTLTDLSTKLSLSPLAENTSDYTETDPSPEEDFSDTGPPVRPQNLRTNPGHPISLSCDATPLSPEDDGYFGAEGCVDECLSSGNTFEGVRRQSAPDRVDVDPNASSDQTLGTKRHGIADFLTRSLFSWKPKESRAVASHSAPGWKLFGKIQLRDNPLKDSRTIQQEYEFRAGPATGPPLHPPPTRRKNLEFEPLSTTALILEDRPANLPAKSEEESQRHRQEYSEMVAGAKRREMKEAQKKKRQMKERYRQEENIASAMVIWNSEVLPNWESMRNTRRVRDLWWQGVPPSVRGKVWCLAIGNELNITPELYEIFLSRAKEKWRSFSETSSVNENEDCGVSLADRESSLDLIKLDISRTFPSLYIFQKGGPYHDILHSVLGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQMAFFRVDHDLMLKYFAAFEVFFEENLPRLFQHFQNNSLTPDFYLIDWIFTLYSKSLPLDVACRVWDVFCRDGEEALFRTGLGILRLYQDVLLQMDFIHSAQFLSRLPENTPAHTLFSCIANTQMISNNRRWNQVFSTLIKDRLKETDKISNSSSNSNSPALRS", "length": 823, "header": "tr|A0A8M9PFQ4-1|A0A8M9PFQ4_DANRE Isoform 1 of TBC1 domain family member 12 OS=Danio rerio OX=7955 GN=tbc1d12a PE=4 SV=2 CANONICAL=A0A8M9PFQ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:563626", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563626", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E7FDW4-1", "protein_name": "TBC1 domain family member 12 isoform X1", "gene_name": "tbc1d12b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGYSPSGVQKSSVISEHCGYFVDSPVKLMVESSSSGGRGAEEGRPPPRIADVTDRQENIMQGMFSNSGASQREKGQLQSSQEHEATESCDEVNLPCGAKLPNGHASHNAPERVACKSSSPAGSCVSSEDDHGIANGELLVDSGSAGDAVSSAFCSGETPDEAGESLETQAGETLEALDQAERSSTDHCLGLQSSECNEGKLHRRSSTSPSPLKHSLRTFSSSTFLNTDSASLSPNDDDDEDETFSTSDRPDDLRFMDVSLKSRNTYEISRRQSAPDNIPGVLSVAAVDLTLGQRKQGISDIFSRSLFTRKQREAQSAPGWKLFGKVPLRESPPKDSKTIQQESNPGNLTSVSTPNLLSSGEYEAKVCKSGQSPSLPAQSRRKNLEFEPLSTTALILEDRPANLPAKSEEEAQRHRQEYDEMVAEAKKRELKEAQKKKKQMKERFKQEESIANAMVVWNTEILPNWESMRGTRRVRDLWWQGLPPNVRGKVWSLAVGNELNITSDLYEIFLSRAKERWKSFRETGSEIESDVDSADRESSLDLIKLDISRTFPSLFIFQKGGPYHDLLHSVLGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQMAFFRVDHELMLKYFAAFEVFFEENLPRLFNHFKSYNLTPDLYLIDWIFTLYAKSLPLDVACRVWDVFCRDGEEFLFRTGLGILRLYEELLLQMDFIHSAQFLTRLPDDTPPERLFSCIASTQMISSNRKWTQVFNALIKDKEMEKSSVPSVKNS", "length": 771 }, "evidence": [ { "id": "HGNC:29082", "url": "https://alliancegenome.org/gene/HGNC:29082#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0R7T9-1", "protein_name": "TBC1 domain family member 12", "gene_name": "Tbc1d12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMGPEDAGACSGRNAELLPVPGPMGQDGKTVPATGGFSGGAVAAEPPGEAGEEEAPPPRQLLQRYLAAAAGPLQPGLGGVEAEAAAVPAARGSGMTNGDSGFLLLQDRRGPEEARRRRTCGRPCLAEPADEGVDGAGGLDDWAAPLEDPLRSCCLAAGDTDDPDPTATTSAGRDVGSAESSLGLPDARFGSRNTFEVSRRQSAGDLLPSAGQSAPLPAAEQGPGGTTVRARRSGGFADFFARNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTSKIIQQEYEARTGRTCKVPPQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEESIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSESSSDSDMEGLSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNRPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVTKDIKEGDKNNSPALKS", "length": 693 }, "evidence": [ { "id": "HGNC:29082", "url": "https://alliancegenome.org/gene/HGNC:29082#orthology", "database": "AGR" }, { "id": "RGD:9377071", "url": "https://alliancegenome.org/gene/RGD:9377071#orthology", "database": "AGR" }, { "id": "MGI:2384803", "url": "https://alliancegenome.org/gene/MGI:2384803#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3920", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3920#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60347-1", "protein_name": "TBC1 domain family member 12", "gene_name": "TBC1D12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGPEDAGACSGRNPKLLPVPAPDPVGQDRKVIRATGGFGGGVGAVEPPEEADEEEEADEEEETPPRQLLQRYLAAAGEQLEPGLCYCPLPAGQAGAPPPSAAPRSDACLLGSGSKHRGAEVADGRAPRHEGMTNGDSGFLPGRDCRDLEEARGLARAGGRESRRRRPYGRLRLEGPGDEDADGAGSPSDWASPLEDPLRSCCLVAADAQEPEGAGSDSGDSPASSCSSSEDSEQRGVGAGGPEEGAPPATSAERTNGGAEPRLGFSDIHFNSRNTFQVSRGQSARDHLPPAGPPVPLPAAEQGPAGASARARRSGGFADFFTRNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTSKIIQQEYEARTGRTCKPPPQSSRRKNFEFEPLSTTALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEENIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVMKDIKEGDKNSSPALKS", "length": 775 }, "evidence": [ { "id": "HGNC:29082", "url": "https://alliancegenome.org/gene/HGNC:29082#orthology", "database": "AGR" }, { "id": "RGD:9377071", "url": "https://alliancegenome.org/gene/RGD:9377071#orthology", "database": "AGR" }, { "id": "MGI:2384803", "url": "https://alliancegenome.org/gene/MGI:2384803#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3920", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3920#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6A039-1", "protein_name": "TBC1 domain family member 12", "gene_name": "Tbc1d12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMGPEDAGACSGRNAELLPVPGPMGQDGKTVPATSGFSGGAVAAEPPEEAGEEEAPPPRQLLQRYLAAAAGPLKPGLGGAEAEEAAAAAVPAARGSGMTNGDSGFLLRQDRRGPEEARRRRTCGRPCLLEPADEGVDGAGGLDDWAAPLEDPLRSCCLAAGDTDDPDPAAATPAGRAVESAEPSLGLPDARFGSRNTFEVSRRQSAGDLLPSAGPSAPLPAAEQGPGGTTARARRSGGFADFFARNLFPKRTKELKSVVHSAPGWKLFGKVPPRENLQKTSKIIQQEYEARTGRTCKAAPQSSRRKSFALEPLSTTALILEDRPPNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEESIASAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLSRAKERWKSFSESSSENDTEGLSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSILGAYTCYRPDVGYVQGMSFIAAVLILNLEEADAFIAFANLLNKPCQLAFFRVDHSMMLKYFATFEVFFEENLSKLFLHFKSYNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDGEEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPEDITSEKLFSCIAAIQMQNSTKKWTQVFASVAKDIKEGDKNTSPALKS", "length": 696 }, "evidence": [ { "id": "HGNC:29082", "url": "https://alliancegenome.org/gene/HGNC:29082#orthology", "database": "AGR" }, { "id": "RGD:9377071", "url": "https://alliancegenome.org/gene/RGD:9377071#orthology", "database": "AGR" }, { "id": "MGI:2384803", "url": "https://alliancegenome.org/gene/MGI:2384803#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3920", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3920#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4" } ], "pmid": "" }, { "name": "small GTPase binding", "id": "GO:0031267", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031267", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasmic vesicle", "id": "GO:0031410", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031410", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4" } ], "pmid": "" }, { "name": "vacuole", "id": "GO:0005773", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005773", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" }, { "start_pos": 695, "end_pos": 697, "annotation": "n_glycosylation_sequon" }, { "start_pos": 811, "end_pos": 813, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PFQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFQ4" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 522, "end_pos": 732, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 541, "end_pos": 543 }, { "start_pos": 695, "end_pos": 697 }, { "start_pos": 811, "end_pos": 813 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PFR9-1", "uniprot_ac": "A0A8M9PFR9", "uniprot_id": "A0A8M9PFR9_DANRE", "mass": { "chemical_mass": 51342.0, "monoisotopic_mass": 51342.0 }, "refseq": { "ac": "XP_021323459", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323459" }, "gene_names": [ { "name": "LOC100001178", "type": "recommended", "evidence": [ { "id": "A0A8M9PFR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFR9" } ] }, { "name": "LOC100001178", "type": "synonym", "evidence": [ { "id": "XP_021323459", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323459" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PFR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFR9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021323459", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323459" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021323459.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323459", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323459" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFR9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFR9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100001178", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFR9", "locus": {} } ], "crossref": [ { "id": "A0A8M9PFR9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PFR9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100001178", "url": "https://www.ncbi.nlm.nih.gov/gene/100001178", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100001178", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001178", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PFR9", "url": "https://www.orthodb.org/?gene=A0A8M9PFR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_021323459", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323459", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PFR9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTLRATSHGELQALASLKSPASDSGFRSLSHSSSNMGGQFESIEEIKGVSKPTHLPRRPVRAVRPVSAFTTSGSFMQINHLQGELVRKRKECEDLKKENKYLSGEIHMERIMMRTESELTMRNLRNLNQELQAQVKELKQKLHVSQQRATLCSRAAEDADRARAEAEKSRALAESRALDNRQQKELAVADKTQLGEELQLLRTEHNDVQLLLAQAEKNYFETKLKLDRVSGEKQAVLEENRILEDDRNTLRHKLKELTEENVKIMEKEVNSRRRALVAEEQRERANKAQQEAEQERHLSERERQERTRECLSWREKHHTLAEVIRAQEELKSLRQNKACQANIKNYFLCVTESDQRVKILKNQDGSPRNFTEGEPVYISTPDLSSDDSERSSGSRAMFRVAAPRARQDTSPAQFRELSPLADSHESGFSRRNRKVEYFWIPTDEE", "length": 445, "header": "tr|A0A8M9PFR9-1|A0A8M9PFR9_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100001178 PE=4 SV=2 CANONICAL=A0A8M9PFR9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PFR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFR9/entry#A0A8M9PFR9-1", "sequence": { "sequence": "MTLRATSHGELQALASLKSPASDSGFRSLSHSSSNMGGQFESIEEIKGVSKPTHLPRRPVRAVRPVSAFTTSGSFMQINHLQGELVRKRKECEDLKKENKYLSGEIHMERIMMRTESELTMRNLRNLNQELQAQVKELKQKLHVSQQRATLCSRAAEDADRARAEAEKSRALAESRALDNRQQKELAVADKTQLGEELQLLRTEHNDVQLLLAQAEKNYFETKLKLDRVSGEKQAVLEENRILEDDRNTLRHKLKELTEENVKIMEKEVNSRRRALVAEEQRERANKAQQEAEQERHLSERERQERTRECLSWREKHHTLAEVIRAQEELKSLRQNKACQANIKNYFLCVTESDQRVKILKNQDGSPRNFTEGEPVYISTPDLSSDDSERSSGSRAMFRVAAPRARQDTSPAQFRELSPLADSHESGFSRRNRKVEYFWIPTDEE", "length": 445, "header": "tr|A0A8M9PFR9-1|A0A8M9PFR9_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100001178 PE=4 SV=2 CANONICAL=A0A8M9PFR9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100001178", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001178", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 369, "end_pos": 371, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 369, "end_pos": 371 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PFT8-1", "uniprot_ac": "A0A8M9PFT8", "uniprot_id": "A0A8M9PFT8_DANRE", "mass": { "chemical_mass": 51053.0, "monoisotopic_mass": 51053.0 }, "refseq": { "ac": "XP_021323484", "name": "perilipin-1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323484" }, "gene_names": [ { "name": "plin1", "type": "recommended", "evidence": [ { "id": "A0A8M9PFT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8" } ] }, { "name": "plin1", "type": "synonym", "evidence": [ { "id": "XP_021323484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323484" } ] } ], "protein_names": [ { "name": "Perilipin-1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PFT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8/entry#names_and_taxonomy" } ] }, { "name": "perilipin-1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323484", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323484" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323484", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323484" } ] } ], "disease": [ { "disease_id": "DOID:0070205", "recommended_name": { "id": "DOID:0070205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070205", "name": "familial partial lipodystrophy type 4", "description": "A familial partial lipodystrophy characterized by autosomal dominant inheritance of loss of subcutaneous adipose tissue primarily from the lower limbs, insulin-resistant diabetes mellitus, hypertriglyceridemia, and hypertension that has_material_basis_in mutation in the PLIN1 gene on chromosome 15q26." }, "synonyms": [ { "id": "DOID:0070205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070205", "name": "FPLD4", "description": "" }, { "id": "DOID:0070205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070205", "name": "PLIN1-related FPLD", "description": "" }, { "id": "DOID:0070205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070205", "name": "PLIN1-related familial partial lipodystrophy", "description": "" }, { "id": "DOID:0070205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070205", "name": "familial partial lipodystrophy associated with PLIN1 mutations", "description": "" }, { "id": "MONDO:0013478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013478", "name": "PLIN1-related familial partial lipodystrophy", "description": "" }, { "id": "MONDO:0013478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013478", "name": "FPLD4", "description": "" }, { "id": "MONDO:0013478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013478", "name": "PLIN1-related FPLD", "description": "" }, { "id": "MONDO:0013478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013478", "name": "FPLD due to PLIN1 mutations", "description": "" }, { "id": "MONDO:0013478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013478", "name": "familial partial lipodystrophy associated with PLIN1 mutations", "description": "" }, { "id": "MONDO:0013478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013478", "name": "familial partial lipodystrophy type 4", "description": "" }, { "id": "MONDO:0013478", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013478", "name": "lipodystrophy, familial partial, type 4", "description": "" }, { "id": "MIM:613877", "resource": "MIM", "url": "https://www.omim.org/entry/613877", "name": "Lipodystrophy, familial partial, 4", "description": "Lipodystrophy, familial partial, 4" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070205" } ] }, { "disease_id": "DOID:0080208", "recommended_name": { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol." }, "synonyms": [ { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "nonalcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "non-alcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "NAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-related steatotic liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MASLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic-associated fatty liver disease", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "NAFLD2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "fatty liver disease, nonalcoholic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "liver disease, alcoholic, susceptibility to, 1", "description": "" }, { "id": "MIM:613282", "resource": "MIM", "url": "https://www.omim.org/entry/613282", "name": "Non-alcoholic fatty liver disease 1", "description": "Non-alcoholic fatty liver disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ] }, { "disease_id": "DOID:9970", "recommended_name": { "id": "DOID:9970", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9970", "name": "obesity", "description": "An overnutrition that is characterized by excess body fat, traditionally defined as an elevated ratio of weight to height (specifically 30 kilograms per meter squared), has_material_basis_in a multifactorial etiology related to excess nutrition intake, decreased caloric utilization, and genetic susceptibility, and possibly medications and certain disorders of metabolism, endocrine function, and mental illness." }, "synonyms": [ { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "inherited obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "genetic obesity (disease)", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "leanness, inherited, autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "monogenic obesity", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, association with, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, early-onset, susceptibility to, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, late-onset, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, mild, early-onset, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, severe, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, severe, and type II diabetes, Autosomal recessive", "description": "" }, { "id": "MONDO:0019182", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019182", "name": "obesity, susceptibility to, Autosomal recessive", "description": "" }, { "id": "MIM:601665", "resource": "MIM", "url": "https://www.omim.org/entry/601665", "name": "Obesity", "description": "Obesity" } ], "unlinked_id_list": [], "evidence": [ { "id": "9970", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9970" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "plin1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050419-213", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-213", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PFT8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PFT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100034463", "url": "https://www.ncbi.nlm.nih.gov/gene/100034463", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100034463", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100034463", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PFT8", "url": "https://www.orthodb.org/?gene=A0A8M9PFT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47138", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47138", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47138:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47138:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03036", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03036", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323484", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323484", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PFT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HWV0", "url": "https://www.uniprot.org/uniprotkb/A0AC58HWV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HWV0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HWV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050419-213", "url": "https://zfin.org/ZDB-GENE-050419-213", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASEKKDTGEVLKDQNVFFRILNIRSVNAALESIEKTYTSTKQSHPIISSVCGLYEKGVSRAGNLAVWSMKPALHVLQPQLVAANSMACKGLDRLEEKVPALQSPPAELAANIKGLMSSTLEAAKDGITCPIKHSSNVVLDKVSSRYQQSKNTLSGGIQYILNSKLVFLAEQRASRALSLTENLIDCILPGTSDKTENDRSTEEQQESYVGASDPMPIFSRLGALASTICRRAFEKTFAQLQLSTHQGHTLVKRIPGLNPLVEFTMSTMRTMGGIIKGFPSSMATYLKDGQQHSPLKEMANDEHGQVKSNGLVSGLGQRLLKVYGSVVANIKKTSRTSFNLAKDGVNIVLGSFGTVREKTLHKLSYYGLIPRRLSKTEGGSQPAEKDGAEECLCGFLVLESNVGNIIHSRNDNSEKQPLKVTEPMDISEETRQLKKKLMKQIPMQHRVVLGGSNKKSPTTEPVGRRV", "length": 467, "header": "tr|A0A8M9PFT8-1|A0A8M9PFT8_DANRE Isoform 1 of Perilipin-1 isoform X1 OS=Danio rerio OX=7955 GN=plin1 PE=3 SV=1 CANONICAL=A0A8M9PFT8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PFT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8/entry#A0A8M9PFT8-1", "sequence": { "sequence": "MASEKKDTGEVLKDQNVFFRILNIRSVNAALESIEKTYTSTKQSHPIISSVCGLYEKGVSRAGNLAVWSMKPALHVLQPQLVAANSMACKGLDRLEEKVPALQSPPAELAANIKGLMSSTLEAAKDGITCPIKHSSNVVLDKVSSRYQQSKNTLSGGIQYILNSKLVFLAEQRASRALSLTENLIDCILPGTSDKTENDRSTEEQQESYVGASDPMPIFSRLGALASTICRRAFEKTFAQLQLSTHQGHTLVKRIPGLNPLVEFTMSTMRTMGGIIKGFPSSMATYLKDGQQHSPLKEMANDEHGQVKSNGLVSGLGQRLLKVYGSVVANIKKTSRTSFNLAKDGVNIVLGSFGTVREKTLHKLSYYGLIPRRLSKTEGGSQPAEKDGAEECLCGFLVLESNVGNIIHSRNDNSEKQPLKVTEPMDISEETRQLKKKLMKQIPMQHRVVLGGSNKKSPTTEPVGRRV", "length": 467, "header": "tr|A0A8M9PFT8-1|A0A8M9PFT8_DANRE Isoform 1 of Perilipin-1 isoform X1 OS=Danio rerio OX=7955 GN=plin1 PE=3 SV=1 CANONICAL=A0A8M9PFT8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HWV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8/entry#A0AC58HWV0-1", "sequence": { "sequence": "MASEKKDTGEVLKDQNVFFRILNIRSVNAALESIEKTYTSTKQSHPIISSVCGLYEKGVSRAGNLAVWSMKPALHVLQPQPNSMACKGLDRLEEKVPALQSPPAELAANIKGLMSSTLEAAKDGITCPIKHSSNVVLDKVSSRYQQSKNTLSGGIQYILNSKLVFLAEQRASRALSLTENLIDCILPGTSDKTENDRSTEEQQESYVGASDPMPIFSRLGALASTICRRAFEKTFAQLQLSTHQGHTLVKRIPGLNPLVEFTMSTMRTMGGIIKGFPSSMATYLKDGQQHSPLKEMANDEHGQVKSNGLVSGLGQRLLKVYGSVVANIKKTSRTSFNLAKDGVNIVLGSFGTVREKTLHKLSYYGLIPRRLSKTEGGSQPAEKDGAEECLCGFLVLESNVGNIIHSRNDNSEKQPLKVTEPMDISEETRQLKKKLMKQIPMQHRVVLGGSNKKSPTTEPVGRRV", "length": 464, "header": "tr|A0AC58HWV0-1|A0AC58HWV0_DANRE Computationally mapped isoform of Perilipin-1 isoform X2 OS=Danio rerio OX=7955 GN=plin1 PE=3 SV=1 CANONICAL=A0A8M9PFT8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100034463", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100034463", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AJ35-1", "protein_name": "Perilipin", "gene_name": "Plin2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEGEERTSSKSGIWSGAGSRLSLRHLFTPGGKMASVAVDPQPSVVTRVANLPLVSSTYDLVSSAYVSTKDQHPYLRSVCEMAEKGVRTVTSVAVTGALPIIQKLEPQIAVANTYACKGLDRMEARLPILNQPTSEIVANARGAVTGAKDVVTTTMAGAKDSVASTVSGVVDKTKGAVTGSVERTKSVVNGGIDTVLGMVQLMSSGVENAISKSELLVDQYLPLTQKELEMEAKKVEGFDMVQKQRYYERLESLSTKICTRAYHQALGRIKDAKQKGQETISQLHSTVHLIEFARKNVHSANQKIQDKLSVSWVEWKRIVGYDDTDESHCAEHIESHTLSMARNLTQQLHTTCQTLLFNVQGLPQNIQDQAKHLGVMAGDIYSAFRNVTSFKEVSDGVLTSSKGQLQKMKESLDEVMDYLVNNTPLNWLMLDFSAFDSTSDTDEVPDIIPLEED", "length": 454 }, "evidence": [ { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QGJ3-1", "protein_name": "Perilipin", "gene_name": "plin3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADNVKTAEKDKEDSQEQQSVISRVGNLPLVSSACGAVYNAYSSTKDSVPLLKGVMEVAESGVRTLGAAASTGSKPILDRLEPQIAAVNEYAIKGLEKVEGNLPILQQPADKLVSDTVGMVYQSVTGAKDAVVGAVMEGVEKTRMAVTGGINTVMGSRVGQMVSNGVDKALTHSEDWVEQNLPISEKELATLAEPRPGEEEGFIVSTRSSYFVRLGKLSAKVRERALEQSLLRARKARDTTHASVTQMTSTMDLLESARVTLTSANQQLAGAPEQLLQRWKEWKEGQPKELQEKVTAETEADGAKDKEQEMESKALLMVRGLSDQLKTACSGVVSSVQGLPGTVQEQLLNARRTAGELQASLSGTKTLTPVLLLQTRQQIGQVRQSLDGVVEYLLNNTPLNWLVGPFAPQITEKGE", "length": 416 }, "evidence": [ { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0R7Z9-1", "protein_name": "Perilipin-5", "gene_name": "Plin5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQRGKDTTLALHSRMSGDQTAQDPGSSLGELDQHNVVKRVVALPLVRATCTAVSGAYNSAKDRHPLLGSACRFAEHCVCSVATCALDHAQPLLEHLQPKLATVNDLACRGLDKLEEKLPFLQQPSDTVVTSAKDAVAKSVTGVVDLAQRGRRWSGELRRSVSQAMDTVLRRSVSQAMDTVLGKSEELVDHFLPMTEAELVALATESQGPEVGSVEEQRQKQGYFVRLGSLSARLRHLAYQHSLGKLRESKHRTQEMLAQLQKTLELIQHMQSRASPTPTFHHPKVQELCGDWSPCLENGYRHSQVELETLALSRSLTLELQSAVDALAGCVRGLPPSAQAKVAEVQRSVDALQATFADAHCLGDVAPTALAEGQDSVAQAHACVDEFLDLVLRAMPLAWLVGPFAPILVERSEPLINLATCVDEVVGDPDPRWAHMDWPAQQRAWEAEPADPGGQEAEPPLGQVKHTMMPELDF", "length": 475 }, "evidence": [ { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60240-1", "protein_name": "Perilipin-1", "gene_name": "PLIN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEKGVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTISTRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLALGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARALEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTDTEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGMAGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAPRPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS", "length": 522 }, "evidence": [ { "id": "HGNC:9076", "url": "https://alliancegenome.org/gene/HGNC:9076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-213", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-213#orthology", "database": "AGR" }, { "id": "MGI:1890505", "url": "https://alliancegenome.org/gene/MGI:1890505#orthology", "database": "AGR" }, { "id": "RGD:3351", "url": "https://alliancegenome.org/gene/RGD:3351#orthology", "database": "AGR" }, { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O60664-1", "protein_name": "Perilipin-3", "gene_name": "PLIN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSADGAEADGSTQVTVEEPVQQPSVVDRVASMPLISSTCDMVSAAYASTKESYPHIKTVCDAAEKGVRTLTAAAVSGAQPILSKLEPQIASASEYAHRGLDKLEENLPILQQPTEKVLADTKELVSSKVSGAQEMVSSAKDTVATQLSEAVDATRGAVQSGVDKTKSVVTGGVQSVMGSRLGQMVLSGVDTVLGKSEEWADNHLPLTDAELARIATSLDGFDVASVQQQRQEQSYFVRLGSLSERLRQHAYEHSLGKLRATKQRAQEALLQLSQVLSLMETVKQGVDQKLVEGQEKLHQMWLSWNQKQLQGPEKEPPKPEQVESRALTMFRDIAQQLQATCTSLGSSIQGLPTNVKDQVQQARRQVEDLQATFSSIHSFQDLSSSILAQSRERVASAREALDHMVEYVAQNTPVTWLVGPFAPGITEKAPEEKK", "length": 434 }, "evidence": [ { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43883-1", "protein_name": "Perilipin-2", "gene_name": "Plin2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAVVDPQQSVVMRVANLPLVSSTYDLVSSAYVSTKDQYPYLRSVCEMAEKGVKTVTSAAMTSALPIIQKLEPQIAVANTYACKGLDRMEERLPILNQPTSEIVASARGAVTGAKDVVTTTMAGAKDSVASTVSGVVDKTKGAVTGSVERTKSVVNGSINTVLGMVQFMNSGVDNAITKSELLVDQYFPLTQEELEMEAKKVEGFDMVQKPSNYERLESLSTKLCSRAYHQALSRVKEAKQKSQETISQLHSTVHLIEFARKNMHSANQKIQGAQDKLYVSWVEWKRSIGYDDTDESHCVEHIESRTLAIARNLTQQLQTTCQTVLVNAQGLPQNIQDQAKHLGVMAGDIYSVFRNAASFKEVSDGVLTSSKGQLQKMKESLDEVMDYFVNNTPLNWLVGPFYPQSTEVNKASLKVQQSEVKAQ", "length": 425 }, "evidence": [ { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P43884-1", "protein_name": "Perilipin-1", "gene_name": "Plin1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMNKGPTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYNSTKEAHPLVASVCNAYEKGVQGASNLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKGTISTRLRSARNSISVPIASTSDKVLGATLAGCELALGMAKETAEYAANTRVGRLASGGADLALGSIEKVVEYLLPPDKVESAPSSGRQKTQKAPKAKPSLLRRVSTLANTLSRHTMQTTARALKRGHSLAMWIPGVAPLSSLAQWGASAAMQVVSRRQSEVRVPWLHNLAASKDENHEDQTDTEGEETDEEEEEEESEAEENVLREVTALPTPLGFLGGVVHTVQKTLQNTISAVTWAPAAVLGTVGRILHLTPAQAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFQDIDNPPAEVERKGSGSRPASPESTARPGQPRAACAVRGLSAPSCPDLDDKTETSARPGLLAMPREKPARRVSDSFFRPSVMEPILGRTQYSQLRKKS", "length": 517 }, "evidence": [ { "id": "HGNC:9076", "url": "https://alliancegenome.org/gene/HGNC:9076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-213", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-213#orthology", "database": "AGR" }, { "id": "MGI:1890505", "url": "https://alliancegenome.org/gene/MGI:1890505#orthology", "database": "AGR" }, { "id": "RGD:3351", "url": "https://alliancegenome.org/gene/RGD:3351#orthology", "database": "AGR" }, { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00G26-1", "protein_name": "Perilipin-5", "gene_name": "PLIN5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEEEAAQIPRSSVWEQDQQNVVQRVVALPLVRATCTAVCDVYSAAKDRHPLLGSACRLAENCVCGLTTRALDHAQPLLEHLQPQLATMNSLACRGLDKLEEKLPFLQQPSETVVTSAKDVVASSVTGVVDLARRGRRWSVELKRSVSHAVDVVLEKSEELVDHFLPMTEEELAALAAEAEGPEVGSVEDQRRQQGYFVRLGSLSARIRHLAYEHSVGKLRQSKHRAQDTLAQLQETLELIDHMQCGVTPTAPACPGKVHELWGEWGQRPPESRRRSQAELETLVLSRSLTQELQGTVEALESSVRGLPAGAQEKVAEVRRSVDALQTAFADARCFRDVPAAALAEGRGRVAHAHACVDELLELVVQAVPLPWLVGPFAPILVERPEPLPDLADLVDEVIGGPDPRWAHLDWPAQQRAWEAEHRDGSGNGDGDRMGVAGDICEQEPETPSCPVKHTLMPELDF", "length": 463 }, "evidence": [ { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BVZ1-1", "protein_name": "Perilipin-5", "gene_name": "Plin5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQRGEDTTLAPHSRMSGDQTAQDPGSSLGELDQQNVVNRVVALPLVKATCTAVSSAYNSAKDRHPLLGSACRLAEHCVCSVTTCALDHAQPLLEHLQPQLATVNDLACRGLDKLEEKLPFLQQPSDMVVTSAKDTVAKSVTGMVDLAQRGRRWSGELRRSMSQAMDMVLGKSEKLVDRFLPMTEAELAVLAAEAEGPEVGTVEEQRQQQGYFVRLGSLSARLRHLAYEHSLGKLRQSKHRTQEMLAQLQETLELIQHMQRGASPSPTFHPPKTQELWGSWSPCLENGRSHSEVELETLALSRSLTLELQNAVDALAGCVRGLPPSAQAKVAEVQRSVDALQATFADAHCLGDVAPTALAEGRGSVARAHACVDEFLDLVLRAMPLPWLVGPFAPILVEQSEPLINLATCVDEVVGDPDPRWAHMDWPAQKRAWEAESADPGGQEAEPPRGQGKHTMMPELDF", "length": 463 }, "evidence": [ { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CGN5-1", "protein_name": "Perilipin-1", "gene_name": "Plin1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMNKGPTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYNSTKEAHPLVASVCNAYEKGVQGASNLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKGTISTRLRSARNSISVPIASTSDKVLGATLAGCELALGMAKETAEYAANTRVGRLASGGADLALGSIEKVVEFLLPPDKESAPSSGRQRTQKAPKAKPSLVRRVSTLANTLSRHTMQTTAWALKQGHSLAMWIPGVAPLSSLAQWGASAAMQVVSRRQSEVRVPWLHNLAASQDESHDDQTDTEGEETDDEEEEEESEAEENVLREVTALPNPRGLLGGVVHTVQNTLRNTISAVTWAPAAVLGTVGRILHLTPAQAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDIDNPSAEAERKGSGARPASPESTPRPGQPRGSLRSVRGLSAPSCPGLDDKTEASARPGFLAMPREKPARRVSDSFFRPSVMEPILGRAQYSQLRKKS", "length": 517 }, "evidence": [ { "id": "HGNC:9076", "url": "https://alliancegenome.org/gene/HGNC:9076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-213", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-213#orthology", "database": "AGR" }, { "id": "MGI:1890505", "url": "https://alliancegenome.org/gene/MGI:1890505#orthology", "database": "AGR" }, { "id": "RGD:3351", "url": "https://alliancegenome.org/gene/RGD:3351#orthology", "database": "AGR" }, { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99541-1", "protein_name": "Perilipin-2", "gene_name": "PLIN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASVAVDPQPSVVTRVVNLPLVSSTYDLMSSAYLSTKDQYPYLKSVCEMAENGVKTITSVAMTSALPIIQKLEPQIAVANTYACKGLDRIEERLPILNQPSTQIVANAKGAVTGAKDAVTTTVTGAKDSVASTITGVMDKTKGAVTGSVEKTKSVVSGSINTVLGSRMMQLVSSGVENALTKSELLVEQYLPLTEEELEKEAKKVEGFDLVQKPSYYVRLGSLSTKLHSRAYQQALSRVKEAKQKSQQTISQLHSTVHLIEFARKNVYSANQKIQDAQDKLYLSWVEWKRSIGYDDTDESHCAEHIESRTLAIARNLTQQLQTTCHTLLSNIQGVPQNIQDQAKHMGVMAGDIYSVFRNAASFKEVSDSLLTSSKGQLQKMKESLDDVMDYLVNNTPLNWLVGPFYPQLTESQNAQDQGAEMDKSSQETQRSEHKTH", "length": 437 }, "evidence": [ { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DBG5-1", "protein_name": "Perilipin-3", "gene_name": "Plin3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSNGTDAPAEAQAAMEEPVVQPSVVDRVAGLPLISSTYGMVSAAYTSTKENYPHVRTVCDVAEKGVKTLTTAAVSTAQPILSKLEPQIATASEYAHRGLDRLQESLPILQQPTEKVLADTKELVSSTVSGAQEMVSSSVSSAKETVATRVTGAVDVTLGAVQNSVDKTKSAMTSGVQSVMGSRVGQMVISGVDRVLVKSEAWADNRLPLTEAELALIATPPEDSDMASLQQQRQEQNYFVRLGSLSERLRNHAYEHSLGKLQNARQKAQETLQQLTSVLGLMESVKQGVDQRLGEGQEKLHQMWLSWNQKTPQDAEKDPAKPEQVEARALSMFRDITQQLQSMCVALGASIQGLPSHVREQAQQARSQVNDLQATFSGIHSFQDLSAGVLAQTRERIARAREALDNTVEYVAQNTPAMWLVGPFAPGITEKTPEGK", "length": 437 }, "evidence": [ { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VXY7-1", "protein_name": "Lipid storage droplets surface-binding protein 2", "gene_name": "Lsd-2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASAEQKHATGNGTTGNGTAMNDVDQPKDAKDLLPHLESLERIIKLPVVNAAWDKSQDVYGKVKGKNRVFEWALTAAEDCVTRAVTTAAPFVTKLDRPIAYVDQTLVKGIDKLEVKAPIIKDTPQEIYNQAKSKVIDVVQPHLERVVKFKAAGQQKAASLKDLAWQKANEVLATQYGSLAVNGVDTTTALAERLLEYYFPKCESDVEEDNDDKQNAVVQNGKSSENDMPVPASEDPVLHTVQTVGRLSNKISRRVYRNVSRQIKQVQKGNINDYLSSLIAALKLHQYINFINSSMGTNVEQSGGSSSDACSPFGTTTSTTTTTTTSSTSNNKPVVALPHVAKSKRAPAVSSQ", "length": 352 }, "evidence": [ { "id": "HGNC:9076", "url": "https://alliancegenome.org/gene/HGNC:9076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-213", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-213#orthology", "database": "AGR" }, { "id": "MGI:1890505", "url": "https://alliancegenome.org/gene/MGI:1890505#orthology", "database": "AGR" }, { "id": "RGD:3351", "url": "https://alliancegenome.org/gene/RGD:3351#orthology", "database": "AGR" }, { "id": "FB:FBgn0030608", "url": "https://alliancegenome.org/gene/FB:FBgn0030608#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "lipid metabolic process", "id": "GO:0006629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006629", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8" } ], "pmid": "" }, { "name": "positive regulation of triglyceride storage", "id": "GO:0010890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010890", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8" } ], "pmid": "" }, { "name": "lipid storage", "id": "GO:0019915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019915", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PFV7-1", "uniprot_ac": "A0A8M9PFV7", "uniprot_id": "A0A8M9PFV7_DANRE", "mass": { "chemical_mass": 93956.0, "monoisotopic_mass": 93956.0 }, "refseq": { "ac": "XP_021323509", "name": "extracellular calcium-sensing receptor isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323509" }, "gene_names": [ { "name": "olfcg9", "type": "recommended", "evidence": [ { "id": "A0A8M9PFV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFV7" } ] }, { "name": "olfcg9", "type": "synonym", "evidence": [ { "id": "XP_021323509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323509" } ] } ], "protein_names": [ { "name": "Extracellular calcium-sensing receptor isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8M9PFV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFV7/entry#names_and_taxonomy" } ] }, { "name": "extracellular calcium-sensing receptor isoform X2", "type": "synonym", "evidence": [ { "id": "XP_021323509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323509" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021323509.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323509" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFV7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFV7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "olfcg9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFV7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PFV7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PFV7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100003331", "url": "https://www.ncbi.nlm.nih.gov/gene/100003331", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100003331", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003331", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PFV7", "url": "https://www.orthodb.org/?gene=A0A8M9PFV7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061:SF528", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061:SF528", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323509", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PFV7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PFV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HV83", "url": "https://www.uniprot.org/uniprotkb/A0AC58HV83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HV83-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HV83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081029-6", "url": "https://zfin.org/ZDB-GENE-081029-6", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLLYLCTLLLFFKLKVSVGNASCKIMGEPKYPLLFKDGDVTIGALFPVHSIETAPSFEFTQKPQLLSCSSVNLRDFRLAQILIFAIEEINRSESLLPKLSLGYKIYDTCSSKLSSMSATMALMNSFEFAGRDKCNGQTSVHAIIGETESSATVILTRTTGPFKIPVISHAASCECLSSRKEYPSFFRTISSDYHQGRALAYIVKHLGWSWVGAVNSDNDYGNYGMAIFLNTAHKEGICVEYSEKFYRTEPEKLKKVVDTIKKSTAKVIVAFISFLEMRLLVEQLSAENITGLQIVGVEGWTTSKSLITPKTLNVLRGSLGFAMRKIYIEGFAEYVLKPFWDTAFPCIPNQRNDSWVILNCSRYQDLLVLKNYIEDVPEHRFSINVYNAVYAVAHALHSLFKCKEQEGCEKDLLTQPQQVVDALKKVNFTVKMGDRVWFDSTGATLAQYEVVNWQQNSDGSVNFKKVGYYDASLPPDQRFVLNIKEILWAGGNLKKPRSVCSESCPPGTRKAAQKGRPICCYDCIPCADGEISNDTDSNNCKQCQGEYWSNADKNKCVQKSVEFLSFTEVMGIVLVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTQWSCMLRHTAFGITFVLCISCVLGKTLLVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTFIQVLICVLWLSISPPFPHKNMKYYEEKIILECSLGSTIGFWAILGYIGLLAALCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSISLLLCIFAPKCYIILLKPEQNTKQYMLGKTTSKFY", "length": 839, "header": "tr|A0A8M9PFV7-1|A0A8M9PFV7_DANRE Isoform 1 of Extracellular calcium-sensing receptor isoform X2 OS=Danio rerio OX=7955 GN=olfcg9 PE=3 SV=2 CANONICAL=A0A8M9PFV7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PFV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFV7/entry#A0A8M9PFV7-1", "sequence": { "sequence": "MLLYLCTLLLFFKLKVSVGNASCKIMGEPKYPLLFKDGDVTIGALFPVHSIETAPSFEFTQKPQLLSCSSVNLRDFRLAQILIFAIEEINRSESLLPKLSLGYKIYDTCSSKLSSMSATMALMNSFEFAGRDKCNGQTSVHAIIGETESSATVILTRTTGPFKIPVISHAASCECLSSRKEYPSFFRTISSDYHQGRALAYIVKHLGWSWVGAVNSDNDYGNYGMAIFLNTAHKEGICVEYSEKFYRTEPEKLKKVVDTIKKSTAKVIVAFISFLEMRLLVEQLSAENITGLQIVGVEGWTTSKSLITPKTLNVLRGSLGFAMRKIYIEGFAEYVLKPFWDTAFPCIPNQRNDSWVILNCSRYQDLLVLKNYIEDVPEHRFSINVYNAVYAVAHALHSLFKCKEQEGCEKDLLTQPQQVVDALKKVNFTVKMGDRVWFDSTGATLAQYEVVNWQQNSDGSVNFKKVGYYDASLPPDQRFVLNIKEILWAGGNLKKPRSVCSESCPPGTRKAAQKGRPICCYDCIPCADGEISNDTDSNNCKQCQGEYWSNADKNKCVQKSVEFLSFTEVMGIVLVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTQWSCMLRHTAFGITFVLCISCVLGKTLLVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTFIQVLICVLWLSISPPFPHKNMKYYEEKIILECSLGSTIGFWAILGYIGLLAALCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSISLLLCIFAPKCYIILLKPEQNTKQYMLGKTTSKFY", "length": 839, "header": "tr|A0A8M9PFV7-1|A0A8M9PFV7_DANRE Isoform 1 of Extracellular calcium-sensing receptor isoform X2 OS=Danio rerio OX=7955 GN=olfcg9 PE=3 SV=2 CANONICAL=A0A8M9PFV7-1" }, "locus": {} }, { "isoform_ac": "A0AC58HV83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFV7/entry#A0AC58HV83-1", "sequence": { "sequence": "MQLSSFFKMLLYLCTLLLFFKLKVSVGNASCKIMGEPKYPLLFKDGDVTIGALFPVHSIETAPSFEFTQKPQLLSCSSVNLRDFRLAQILIFAIEEINRSESLLPKLSLGYKIYDTCSSKLSSMSATMALMNSFEFAGRDKCNGQTSVHAIIGETESSATVILTRTTGPFKIPVISHAASCECLSSRKEYPSFFRTISSDYHQGLQIVGVEGWTTSKSLITPKTLNVLRGSLGFAMRKIYIEGFAEYVLKPFWDTAFPCIPNQRNDSWVILNCSRYQDLLVLKNYIEDVPEHRFSINVYNAVYAVAHALHSLFKCKEQEGCEKDLLTQPQQVVDALKKVNFTVKMGDRVWFDSTGATLAQYEVVNWQQNSDGSVNFKKVGYYDASLPPDQRFVLNIKEILWAGGNLKKPRSVCSESCPPGTRKAAQKGRPICCYDCIPCADGEISNDTDSNNCKQCQGEYWSNADKNKCVQKSVEFLSFTEVMGIVLVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTQWSCMLRHTAFGITFVLCISCVLGKTLLVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTFIQVLICVLWLSISPPFPHKNMKYYEEKIILECSLGSTIGFWAILGYIGLLAALCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSISLLLCIFAPKCYIILLKPEQNTKQYMLGKTTSKFY", "length": 752, "header": "tr|A0AC58HV83-1|A0AC58HV83_DANRE Computationally mapped isoform of Extracellular calcium-sensing receptor isoform X1 OS=Danio rerio OX=7955 GN=olfcg9 PE=3 SV=1 CANONICAL=A0A8M9PFV7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100003331", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003331", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JYA5-1", "protein_name": "Vomeronasal 2 receptor, 16", "gene_name": "Vom2r16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHTLILFFLLLNIPLLVVSLIHPRCFWRMKQNEEKNGNLKTGCIFAFGVVKWPVEKEYYYNILSTQTNTENHQFSLALAFSMDEINKNPDLLPNKSLLFDFPFYSCKSHSELTTLIHGSVQQYDIFPNYVCNNETMCTLLLTGPNWKISVILRTYLDLYKSQQFLQLTYGPFHPVLSDNEQFPYLYQMAPKETSLALALVSFLIHFSWNWIGLAISDNDQGNQFLSYLRTEMGKYTVCFAFVNMIPVNMQLFMTRTDVYYNQIITSSTNVVIVYGDTDSTLALGFKMWKSLGVQRIWVTTSEWDVITSKRDFTFDTFHSIIAFQHHHGEISGFKNFVQTLNPFKYSDKYLVKLEWMYFNCEISASNCKTLKNCLYNESFEWLSEQTFDMAFSDGTHDIYNAAYAVAHALHEFFLQQGDNQQKYRGKWPNSVCLKLHSLLKKTHFTNPVGDRVIMNQREKMQEEYDIFYIWNFPQGLGLKVKIGEFSPYYSSGKQLWLFEDMIEWTTGNRQMPSSVCNSDCGPGFRKIWKEGMSTCCFDCIHCQENEISNETNVDQCVKCPEDQYANPEQNHCIHKALIFLTYQETLGMTLSLVALCLSTLTAAILGVFVKYHTTPIVKANNCRLTYILLITLIFCFLCPLLYIGHPNSVTCVLQQVTFGIVFTVAISTVLAKTITVILAFKVTAPQRMIKYFLISGVFNYIIPICTLIQVFVCTLWLGTSPPSVDFDPQSEHGHIIIVCNKGSVTAFYCMLGYLSCLALGSFTLAFLSRNLPGTFNEAKFLTFSMLVFCSVWITFLPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFIPKCYIILLRPERNSLQRIREK", "length": 849 }, "evidence": [ { "id": "RGD:1593384", "url": "https://alliancegenome.org/gene/RGD:1593384#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYG8-1", "protein_name": "Vomeronasal 2 receptor, 12", "gene_name": "Vom2r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTLILSFLLLNIPLQVTGFIYPTCSWRIKENKDKSGNERIGCFFLIQAVQKPVEKEYFSHFFNTQKHTEIHKYSLVLAFSMIEVNRNPDLLPNMSLVFSFREIICGWQPELSIFIEVNLDDYGVLPNYTCKDDSLCGVVLTGLNWAPTLLLYTILNNFKSQQFPHLTYGHYHPVPSDHENFPYLYQMASDDTSLALALVSFIIHFSWNWIGLAFSDNDQGTHFLSYLKRGMEKNAVCLAFVSMIPVDMHLYMSRAEVYYSQILTSSANVVIIYGDTGSTLAVSFRMWESLGLQRLWITTTQLDVTPSMKENIYGLFAFGHHHGVISGFKNFVQTLNPVTYSNDNLAKLEWMHFNCEVSASKWKTLKNFSSNHSLEWLMENTFEMTFSEGSYNIYNAVYTVAHVLHKMTFQKFHNLPNAKGKVQNYVCNKLGAPLRKIHFTNPVGDRINMNREDKLQEEYDIFYIWNFPQGLAFKVKIGLFSPYFINGQQLHLSGDMIEWARGSTQMPTSVCSADCGPGFRKFRKKEMSACCFDCSPCPENEISNETNMEMCVLCPEDKYANTGQNDCIPKALIFLSYEDHLGMALSLMALGFSAFTAVVLGIFVKHHSTPIVKANNRTLTYILLLSLIFCFLCPLLFIGHPDSVTCILQQITFGVLFTVAISTVLAKTITVILAFKVTAPQRMMKYFLLSGVSMYIIPICTLIQVIVCAVCLGVSPPSVDIDAQSEHGHIIVVCNNGSVTCFYSVLGYLACLTFVSFTLAFLSRNLPGAFNEAKSITFSMLVVCSVWVTFLPVYHSTKGKIMVAVEIISILASSSGMLVCIFIPKCYIILFRPEKNSLKMIREKSPSHTHIS", "length": 853 }, "evidence": [ { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JZT8-1", "protein_name": "Vomeronasal 2 receptor, 13", "gene_name": "Vom2r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTLILSFLFLNIPFQVTGFIYPTCSWRIKENKDKSGNERIGCFFLIQAVQKPVEKEYFSHFFNTQKHTEIHKYSLVLAFSMIEVNRNPDLLPNMSLVFSFREIICGWQPELSIFIEVNLDDYGVLPNYTCKDESLCGVALTGVNWAPTLLLYTILNNFKSQQFPHLTYGHFHPVLSDHENFPYLYQMASDDTSLALALVSFIIHFRWNWIGLAISDNDQGTQFLSYLKRGMEKNAICLAFVSMIPVNMHLYMSRAEVYYSQIMTSSANVVIIYGDTGSTLAVSFRMWESLGLQRLWITTTQLDVTPSMKDNVYGLFAFGHHHGVISGFKNFVQTLNPVTYSNENLAKLEWMHFNCEVSASKWKTLKNFSSNHSLEWLMEHTFEMTFSEGSYNIYNAVYTVAHVLHEMTFQKFHNLPNAKGKVENYVCNKLGAPLRKIHFTNPVGDRINMNREDKLQEEYDIFYIWNFPQGLAFKVKIGLFSPYFINGQQLHLSGDMIEWARGSTQMPTSVCSADCGPGFRKFRKKEMSACCFDCSPCPENEISNETNMEMCVLCPEDKYANTGQNDCIPKALIFLSYEDHLGMALSLMALGFSAFTAVVLGIFVKHHSTPIVKANNRTLTYILLLSLIFCFLCPLLFIGHPDSVTCILQQITFGVLFTVAISTVLAKTITVILAFKVTAPQRMMKYFLLSGVSMYIIPICTLIQVIVCAVCLGVSPPSVDIDAQSEHGHIIVVCNNGSVTCFYSVLGYLACLTFVSFTLAFLSRNLPGAFNEAKSITFSMLVVCSVWVTFLPVYHSTKGKIMVAVEIISILASSSGMLVCIFIPKCYIILFRPEKNSLKMIREKSPSHTHIS", "length": 853 }, "evidence": [ { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KAL5-1", "protein_name": "Vomeronasal 2 receptor 19 like 1", "gene_name": "Vom2r19l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTMIFLFLLLNIPLLMVDFIHPRCFWRMKQNEDKDGNPGTGCTFFLQSVHWPVEKEYYSDIFNIQMHNENHKYALALAFAIYEINGNPDLLPNMSLIFEFTRDVCDWESQLNSVIQSSLKNHNILPNYICKEFTKCPMALTGLNWTTTLKLHTILNNFISQQFLQVTYGPFHPVLSDNEKFPYLYQMASDDKSLALALVSFIIHFGWNWVGLAISNNDQGIQFLSYLRREMEKGTVCFAFVNMIPVNMHLYMSRAEMYYNQIMTSSTNVVILYGDTDSTLAVSFRMWESLGIEKIWVTNSWWAATLSKKDHTFDNLYGTYAFGQHHGEISGFKNFVQTLNPAKYSDEHLVKLEWMYFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFTGGSYDIYNAVYSFAHALHEMTFQIFDNLPKDNGREHNYSCKKLCSFLRKTSFTNPVGDRVNMNQRHKQKEEYDIFYIWNFPQGLGIKVKIGMFSPYFPNGQQLHLSEDVLEWAKGSAQMPTSACSADCGPGFRKSWKDGMATCCFHCKPCPENEISNETNVDVCARCPDDQYANIEQNRCIPKAVVFLSYEEPLGMALSLISLGFSVFTIVLLGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSAICILQQITFGVVFTVSVSTVLAKTITVILAFKVTASQRMMKYFLVSRVPNYIIPTFTLFQVILCAVWLGASPPSIDIDAKSEHGHIIIACHKGSVTTFYCVLGYLGTLASGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKIMVAVEIFSTLASSAGMLGCIFVPKCYTVLFRQDQNSLVMIRMKSSSHAHIS", "length": 857 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0R4IS27-1", "protein_name": "Olfactory receptor CG6 precursor", "gene_name": "olfcg6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFLFYTILLFHLLHTKVENSLCRIMGDSNYPLFSKNGDVSIGGIFAIHRKETLPSFEFMQKPQPLSCSSVNLRDFRLAQTMIFAVEEINRSKSLLPNVSIGYKIYDTCGSRLSTMTAIMGLMNGQDFSTEDRCNGQSRLHAIIGESESSATIVLSRTTGPFRIPVISHSSSCECLSNKKDYPSFFRTISSDYHMSRALVYIVKHLDWSWVGAVNSDNDYGNNGMAIFLKAAHEEGICVEYSVKFYRTEPEKLKKVVDTINKGTAKVIVAFVSFVEMGLLIDQLSIQNITGIQMIGVEPWITANTYITSNSFRAMGGSLGFATKYIYIEGFAEYVMTPFWNTAFPCSESDRNHSHYELICSRYEDLLALKNDNKDVNEHRYSSNVYKAVYAVAHSLHGLLNCKEQEGCEKGLTIQPQQVVKALKNINFTIKSGDSVWFDNTGSVVALYEVVNWQKDSDGSFQFKSVGFYDAMMPPYKNLRLNTKNIVWAGGQLEKPRSVCSESCAPGTRKAAQKGRPVCCYDCIPCAEGEISNETDSINCKQCPGEYWSNTERNRCVIKAVEFLSFSEVMGIVLVIFSLFGAGLTVLVAVLFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTKWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPVQQRLSVFAFTLIQVLICVLWLTISPPFPYKNMKYYKEKIILECNLGNTIGFWAVLGYIGLLAALCFLLAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSFGLLVSIFAPKCFIILLKPEQNTKQHVMGKTTCSL", "length": 837 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A140T8U3-1", "protein_name": "Vomeronasal 2, receptor 130", "gene_name": "Vmn2r130", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLILLFLLLNIPLIVADFIYSRCFWRIKQNKDKDGNLGSGCALFIQAVQWPVEKEYFSPILNTQTYTENYKYILVFMFSINEVNRNSDLLPNMSLIFTFSALSCNESQLKSFIHLSLQDHDYFPNYICNDYICGVALVGLKWETTLTLYTILNNFMSHQFLFLNYGPFHPAMSDHEEFPYIYQMASEDTSLALAMVSFIIHFSWNWVGLAISDNDEGIQFLSHLRREMEKNTVCFAFVSMIPVNMHLYMTRTEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLDIKRIWVTTSQWDIITSKKDFTFNNLYGTFAFGHHHGEISGFKNFVQTLDLLKFSDEYLVKLEWMYFNCEDSAPKCKTLKNCSSNHPLEWLMVRTFDMAFTEGSYAIYNAVYAVAHALHELTFQKFDNLRPDNVKGQKYACNKLGSFLRKIHFTNPVGDRVNMNQRNKLQENYDIFYVWNFPQGLRLKVKIGIFSPYFINGQQLHLSEDMLEWARGSTQMLTSVCSADCGPGFRKFRRNGMPACCFDCRPCPENEISNETNVELCVPCPEDQYANTEQNNCIQRAVIFLTYKDPLGMALSLMALCFSAFTAVVLLVFVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCVLQQVTFGVAFTVAVPTVLAKTITIVLAFRVTAPQRMMKYFLVSGASIYIIPICTLIQVIVCAVWLGAAPPSVDIDARSEHGHIIIVCNKGSVSAFYCVLGYLACLAFGSFTLAFLSRNLPSTFNEAKSITFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSTLASGAGMLICIFVPKCYIILFMPDRNSLQMIRKKSSSHAHLS", "length": 855 }, "evidence": [ { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W422-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r54", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSASMWGYRVTQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQKEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSYQSLGKIEETVQKMQKCTAKVVLVFLSNLNFQLILRGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVSSLNAEETVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFVLALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQICLSPGTSTFVVLIASLIQVVLCGVWLATSPPFPDKDMISEPQHIVIQCQEGSGATFFCVLGYLGFLAGGTFSVAFLARGLPDIFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLKQGYCAQQEKQGEMLQRRYKFSGESPEPNI", "length": 878 }, "evidence": [ { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W4A7-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r53", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCTLLSVLFGCLSGSALSGPRVWIIPRQSPRFDRPGDVIVGGSFSIFHFSDGTLSNFTAPPPVLKTSSASMWSYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTCSHAVTQLVIHFQWSWVIILAHDDDFGQQASSLATQMLTPAGVCIEYHLHVPSHQSFGKIEETVQKMQKCTARVVLVFLSNSNFQLILHGLLAVPVSGQVWVSMDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSRIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHNLRNVYFKTSDGNKIMFDANGDLVTQFDIFQGKKTPAGVFHLVHVGLIDPQASSGNKMMVQLKQDLQVSSLNAEITVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTIFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQVCLSSGASTSVVLIASLIQVVLCGIWLITSPPFPDRDMISEPRHTVIQCHEGSGANFFCVLGFLGFLAGGTFSVAFLARGLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHQVQHNRQCEMLQRRCVSSGESLGSSL", "length": 878 }, "evidence": [ { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2WBA1-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r56", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLSCHWLSDPLAGMWLCTLLPVLFGCPSGSALSGARAWLLPRQSPHFDRPGDVIVGGSFSIFRFSNGTLSNFTAPPAGLQTSSVSMWGYRVAQSFVFAIEEINRSTHLLPNLTLGFSIRNSGDSAHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTSSHAVTQLIIHFQWSWVIILAHDDDFGQQASSLASQVLTPAGVCIEFYLYVPSHQSLGKIEETVRKMQKCTARVVLVFLSNYNFQLILYGLLAVPVSGQVWVSKDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCMWPYQNITVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHDMISYEHQDGKGTNSQDFQPWQLLHVLRKVHFKTPDGSEIMFDANGDLVTKFDIFQGQKTPDGVFHLVCVGLIDPQASSGNKMMVQKKMLKYQMKHAQVPTSVCSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCCIILLKPEKNTSSWLRQGHHV", "length": 865 }, "evidence": [ { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2WCY4-1", "protein_name": "Vomeronasal 2, receptor 16", "gene_name": "Vmn2r16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLHAFTISFSLLKFSLILYSLTEPNCFWRIQSNEDNDGDLRSDCGFVLFTYEGPIEEKFYNNVIHFSGTMNNLDLIWNAQQSRNGGHTCDPDLEDGRSSLLIWMLKNSGHEKHRIPARRYEFLLVMYFATDEINRNPYLLPNMSLIFSLIVGMCEDTLGYIEEKYSPQKNRLNFINYNCGIPQTCNIQITGPSWTTSLKLAINSRRPKVFFGPFNPNLSDHDQFPYVHQVSTKDTHLSHAMVSLMLHFKWTWIGLVISDDEQGIQFLSGLREEMQTYAICLAFVNMIPETMQIYMTRADIYDKQIIESTAKVVIIYGEMNSTLEVSFRRWGYLGARRIWITTSQWDVITNEKDFSLDFFHGTITFAHHNGRIAKFNNFLQTMNTSKYPIDVTQTMQDWNYFNCSIFKNSVRKTGQFIFNNTLEWTTQHKIDMVLSEEGHNLYNAVYAVAHTYHELILQQVESQKMPKLKGVFSDCHQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFNIWNFPQGLGLKVKIGSYFPCFPQSQQLCISENMEWATGGALVPTSMCSVTCAAGFRKIHQKHTADCCFDCVLCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGSMTMCFSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLILCFLCSLFFIGQPNHATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTTPGRRMRGMLASGTPNLVIPICSLVQLVLCGIWLVTSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFVPKCFVILVRPDSNFLQKYKDKLFY", "length": 897 }, "evidence": [ { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3Q4EIC8-1", "protein_name": "Vomeronasal 2, receptor 129", "gene_name": "Vmn2r129", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLCAFTISLLFLKFSLILCCWSEPSCFWRIKNSDDNDGDLQRECHFYLGAADTPVEDNFYSSLLKFRIAASEYEFLLVMFFAIDEINRNPYLLPNITLMFSFIGGNCQDLLRVMDQAYTQINGHMNFVNYFCYLDDSCAIGLTGPSWKTSLKLAMHSSMPLVFFGPFNPNLRDHDRLPHVHQVAPKDTHLSHGMVSLMFHFRWTWIGMVISDDDQGIQFLSDLREESQRHGICLAFVNMIPENMQIYMTRATIYDQQIMTSSAKVVIIYGEMNSTLEVSFRRWEELGARRIWITTSQWDVITNKKDFTLNLFHGTITFAHHRVEIPKLNKFMQTMNTAKYPVDISHTILEWNYFNCSISKNSIRMHHITFNNTLEWTSLHNYDMAMSDEGYSLYNAVYAVAHTYHEYIFQQVESQKKAKPKRYFTACQQVSSLMKTRVFMNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYLPCFPQRQKLHISDDLEWAKGGTSPQVPSSVCSVACTAGFRKIYQKETADCCFDCVQCPENEISNETDMEQCVRCPDDKYANIEQTHCLSRAVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKHNDTPIVKANNRILSYILLISLVFCFLCSLLFIGPPDQVTCILQQTTFGVFFTVSVSTVLAKTITVVMAFKLTTPGRRMRGMMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKIVILCNKGSVIAFHVVLGYLGSLALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSTRGRVMVVVEVFSILASSAGLLMCIFVPKCYVILIRPDSNIIKKHKGKVLN", "length": 850 }, "evidence": [ { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I6AGG5-1", "protein_name": "Vomeronasal 2 receptor, 56", "gene_name": "Vom2r56", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADMEKAYTLIVFFLLLRLSFILCSFPEATCFWRINHNENLESNMRKDCGFILFTIPVHLVEDHFRVLLDFPLPVNTYPYVLVMLFAIEEINKNPNLLPNSTLGFTFLGDQCDITSTDLNNLNMLSKSGEMNPNYICEYSFCDVALTGPTWTVSARVGTLLQLFKIPQVMLSVTYGPFHDSLSDRDLFPHLYQIAPKDTSLVLAMVSLMIHFLWKWVGLVILDDDQGVQFLSDMKEEVKTNEICLAFVNMIPANMQLYIERAETYYFQIMTSSANVVIIYGNVNSTLEVSFRRWEMLGIWRLWITTSQWDVISRSRDFTIDSFHGTLSLSHHYQEISTFKHFIQKTNFSAYPEAVSLVRLGWIYLNCSVSVCECKTLNHCLSNTILELLPWHSFDMAMNDERYNIYNAVYAVAHAFHNMRLQQVDIKVLESWEGLIPRCMQVNDFLKNVRLINPIGDPVNINQGRNLDAMYDIFNVLNFPQGYVLKVKVGQFSPYFAHDQQLFLSEDMIEWATGSRQFSTSVCSMPCHPGFKKSHQEGKADCCFDCSRCPANEISNTTDSEECVKCPEDWYADTEQTHCLPKAVTFLAYEDPLGMALVCLALCFSVLTALVLGVFLKHRETPIVKANNRTLSYILLTALIFCFLCSLLFVGNPNTTTCILQQTTFGILFTVSVSTVLAKTLTVVLAFRITLPGRRMRGLMVSRIPKYIIPICTVVQIILYGIWLWTSPPFVDIDTHSEHGCITITCSKGSVMAFYCVLGYLGSLALVSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSSKGKVMVAVEVFSILASSMGLLGCIFIPKCYIILLRPDRNSIQKFRDKTQMNQ", "length": 861 }, "evidence": [ { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK91-1", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "LOC134484845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSLMFHFGWTWIGLVISDDDQGIQFLSDLREEMQRHAICLAFVNMIPETMQTYKTRVKIYDQQIMTSSAKVVVIYGEMNSTLELSFRRWAYLGAQRIWITTSQWDVITHKKDFSLDFFHGTVTFAHHHNDIPVFRNFLQTINTSKYPIDISQSMLQWNHFNCSISKSNNKMDCFTFNNPLEWLAQHTFDMVLSEEGYNLYNAVYAVAHTYHELILQQIESPKMEEPKGVFTDCQQEVSLLKTRVFINPVGELVNMNHKENQCAKYDIFINWNFPQGLGLKVKIGSYFSCLPQSQQLHISEDWEWVTRETLVPSSVCSVTCIAGFRKIHQKQTANCCFDCVQCQENEIANDTDMEQCVRCPDDSYANLEQTKCLQRAVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYRDTPIVKANNRILSYILLISLAFCFLCSLLFIGHPNQATCILQQTTFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRKMMIKGATNLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKVIIICNKGSVTAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTKGKVMVVVEVFSILASSAGLLGCIFVQKCYVLLVRPDLNVLRK", "length": 646 }, "evidence": [ { "id": "RGD:6500225", "url": "https://alliancegenome.org/gene/RGD:6500225#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GK53-1", "protein_name": "Vomeronasal 2 receptor, 33", "gene_name": "Vom2r33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLCTFLFVLLGCLPGSALSEPRSWILPRQSPHFDRPGDVMVGGSFSIFCFSDGTLSNFTAPPTGLQASRVSMWGYRVAQSFVFAIEEINKSTQLLPNLTLGFSIQNSGDSVHGALYETMGFLTGQEEPIPNYTCCHGSPQAALVGDTRSSLSLPMARLLGLYKFSQISYSSSLPSLSDKIQFPSFLRTLPSDLTSCHAVTQLIIRFQWSWLIILSQDDDFGEQASSLATQQLSAAGVCIEFHLDVPSQHSLGKIEETVQKMQKCTARVVLVFLSNSNFQLILSGLLAASVSGQVWVSNDTLHIAMALSIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLHPSQIPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQVCSGNESLKNKPYPFPEVSKIDAAYTAVYSIAHALHDMVACEHQDGIDTNPQDFHPWQLLHVLKKVHFRTPDGSEIMFDANGDLVTKFDILQGQKTLNGVFHLVHVGMIDPQASSGNIMMIQLKEDLQVSSMNAEITVPTSICSERCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALMAILLAGLALLVLGVFLKHRDTPVVRVNNRTLSYFLLISLSLCSLCSLLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTVTVVLAFRVTKSGSRIQVCLSPGASTSVVLIASLIQVVLCGVWLATSPPFPERDMISEPQHIVIQCQEGSGATFFCVLGFLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHCAHQDRQCSLFH", "length": 864 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GKI6-1", "protein_name": "Vomeronasal 2 receptor, 71", "gene_name": "Vom2r71", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKMCAFTISSLLLKFSLILCSFTEPSCFWRIQNNEDNDGDLRSDCGFVLITYEGPIEENFYNNVINFRIPARRYEVFLVLLFATDEINRNPYLLPNMSFMFSRIVGMCEDTLGSLERKYTPQSNSWKFINYNCGIQEVCDVQLTGPSWTTSLKLAINSRNPKVFFGPFNPNLSDHDQFPYVYQVATEDTCLSHAMVSLMLHFRWTWIGLVITDDDQGIQLLTDLREEMERHGMCLAFVNMIPETMQIYMTKAKIYDNQIMTSSAKVVIIYGEMNSTLEVSFRRWAYLAAQRIWITTSQWDVITTRKDFSLDFFHGTFTFAHHNVELPKFRHFMQTMNTSKYPVDISQSMLGWNYFNCSISKNSISKIDHFTLNNTLEWLAQHKFDMFLSEEGYNLYNAVYAVAHTYHELILQVESQKMAEPKGLFTDCQQVALLLKTRAFTTPVGELVNMNHRENQCAKYDISIAWNFPQGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTLIPTSMCSVACIAGFRKIHQKQVTHCCFDCAHCPENEVSNETADMEQCVRCPDDKYANLEQTYCLQRVVSFLAYEDPLGMALGCTALCFSTLTVLILFTFLKYKDTPIVKANNCLLSYILLISLIFCFLCSLLFIGHPNHITCILQQTTFGVFFTVAISTVLAKTITVVMAFKISTPGNRMKGMLTSGAPNLVIPICTLIQLVLCGIWLGTSPPFIDRDIQSEPGKTIVICNKGSIFAFHFTLGYLDSLTLMSFAVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTKGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRTDSNFLQKYKDKFHY", "length": 849 }, "evidence": [ { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL30-1", "protein_name": "Vomeronasal 2 receptor, 3", "gene_name": "Vom2r6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTIAFFPLKFCLILCSLTEPNCFWRIKKIEVYDGDLQNDCGFVLFTLESPIEENFYNHIINFRIPARKYEFFLVMFFATDEINKNPYLLSNMSLIFSFIFGMCEDTMGVLDKAYLHQNNYFDLLNYNCGRKKRCDVKLTGPSWKTSLKLSVNSRAPKIFFGPFNPNLSDHDQFPYIYQIATKDTYLLHGMVSLMFHFEWTWIGLVITDDDQGIQFHSDLREEMQRHAICLAFVIMIPESIKLYNTKFKIYDQQLMTSSAKVTIIYGKMISTLGLSFRRWAYLVARRIWITTSKLDDITYDKDFSLDFFHGTVIFVHHHNDIATFRNFMQTINTSKYPVDISQSMGQWNHFNCSISKNKKKMDFFMLKNPLEWLKQHTFDMVLSEEGYNLYNAVYAVAHTYHELIFQQVESQEMAKPKGLFTDCQKVASLLKTRVFTNPVGELVNMNHKENQCAKYDIFIIWNFPKGLGLKVKIGSYFPCLQQSQHLHISEDWEWVTGETLVPSSVCSETCTAGFRKSHQKQTADCCFDCVQCQENEIANDTDMEQCVRCPDDSYANLEQTECLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYRDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQATFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRKMMIKGATNLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKVIIICNKGSVTAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVIVEVFSILASSAGLLGCIFVQKCYVLLVRPDLNVLQK", "length": 841 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N5X2-1", "protein_name": "Olfactory receptor CW1 precursor", "gene_name": "olfcw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTPVLRAIHLVFFLFYPIQSNSEANCKLWKELDLTVVHKEGDVILAGMFPIHSKGIDQELNFRNQPDQRKCWGFNMRVFRWSQAMIFFIEEINRNPTLLPNITLGYRLYDTCGLIALSLRTALSVVSQPMKRSSSEMCSSPSIPIIIGDSGSTLSMAISRLLNLFHIPLVSYFASCACLSNKHQFPYFFRTIPSDVNQANALARLVKHFGWTWVGTVGADDAYGRTGIDLFTAAVTQLGVCVSYRIIIPKLPTQQQLQDIVRTIRDSSAHVLVAFAIEEDIKPVVDEIVLQNVTGKQWVASEAWVTSTLISTKENFPSLSGTIGFAIRRAEIPGLKHFLDSIQPLADPYNVFAREFWETQFQCTLNTSLPTSSTMDPVNYSHSCTGMERMQDTQSIFNDVSQLRVTYNMYKAVYTVAHALHNLLLCQREHRSALTQQCPDIHNLQPWQVIEVLRKVNYTNMFGDLIYFDENGDPVGSYDIVNWQKGGDDVPVQYITVGRFDSSLPKGQQLVLNQNKIVWHGGTNKVPVSVCSASCPPGYRKVRLEGQPVCCYDCMLCAEGSISNTTDQAECLLCPEDFWSNKHRNYCVPKEIEFLSYLEAFGMVLAAIAILGAVAAISVGVVFFRHRDTPLVRANNSELSFLLLISLTLCFICALTFLGQPSHWACPLRRISFGLTFALCLSCLLSKTLVVLIAFKSTLPGNNTARWFRPPQQRLGVFICSLLQGGVCIAWLTTASPYPVKNTWLYRDRIILECHLGSVVYFCCVLGYIGCLAAFCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSYGVLLCIFAPKCYIIIFMPEKNSKKYLMTQK", "length": 866 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PS22-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcx1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQIYATLLTLCLLLYIRVQCQSNNKYKCIYQGDDDTYSFYQGGDLVLGGIFPLHSSTIPQFFSFTTKPKLIQYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPEKGSGQSCEDTRKQPSPVIVGEASSGVSMAVLRTLGTFQIPLVSYFASCSCLSNKREFPAFMRTMPSDLFQIKALVKLVYYFKWTWLGVIGVDTDYARFAIQLFLKESEKYNICPAYVHIYPVALTQNTVEELVKILKSSSARVILNFSVDSYLYGVLKECRRQNVTNLQWIASEAWATSKVLWDDFGDLLKGTLGFAIRRADIPHLGSYLRSVSSSVAQTSPFFTEFWEETFHCRLNGSLNTHVHEEASYNWPACNGNETLDDVYTLYSDVSQLRVSYNVYKAVYLIAHALHDMSTCDPGKGPFKNGTCGSLYQILPWQLLYYMKRTNFTTLGEEVRFDKNGDPIASYDLMNWQRESDGSLQLVRVGIYDASFKDDKDLVIDESVIMWHRGDKAPESLCSKSCLPGSRKARQKGKPVCCFDCISCAEGEISNQTDSIDCLTCSKDTWPNQSQDQCIPKTLEFLSFQEPLGIILWVFSALGACAALAVLCVFVMYRTTPVIRGNNIELSFLLLLFLCACFLIGLTFLGKPTDWLCQIRYPAFGISFTLCISCILAKTVVVLMAFRATIPGNNVMKWFGPVKQRSSVILCTCVQALICIIWLTTKPPLASYNSKFLSATIIVECSVGSEVGFWCVLGYIGFLSSLCFFLAFLARKLPDNFNEAKFITFSMLIFFAVWITFIPVYVSSSGKYMVAVHVFAILASAFGLLMCIFAPKCYVVLLKPERNDKKSMMKK", "length": 866 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PU52-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWISLNIFLYLSLNCIFAASVVNPGTCQLQGHFKLNGMYQDGDFILGGLFEVHFFTLFPKLSFKSEPEPPYCEKFDMESFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCVMLGMAFRAAISLASGTEEYFSNLNCTGPPPVIGVVGDPGSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVRILSHFGWTWVGLIYSDDDYGIYASVSFQQEMQQFGSCISFSEILPHDNNPKDIQRIMEVIKASTASVVVVFSTSSYLMPLIDEVVLQNLTGRQWIASEAWATSPVFHTPRYLPFLGGTLGIAIRRGEILGLQEFLLHIHASNNPKDNMLKIFWENMFRCSFETRSKDTIGEQEKSICTGHEDLSTTKTPYTDVSGLRASYNVYKAVYALAHALHDLMECEEGRGPFDGNSCGNITNLKPWQLVHYLQKVNFKTGFGDHVSFDENGDALAIYDVLNWHPSSDGSIRLHTVGVVNEGAGTGKVLSLDESALYWNFQTKNPPRSVCSASCPPGTRQAMRKGLPICCFDCLPCGDGEISNATDSTECVTCPDEFWSNFDKNQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHLNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGTMKWFGAAQQRCTVLVLTALQVVICAVWLSNASPTPIKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKKAIIRRETKKR", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q146-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYQDGDFILGGLFEVHFFTVFPDLTFTTNPKSPYCEIFNMEGFQHAQTMAFAIEEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLTSGTEESFLNLNCSGPSPVIGIVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSNRKKYPSFFRTIPSDAFQVRAIVQVLKHFKWTWVGLLYSDDDYGVYAAQSFQQEMRQFGLCAAFSEFLPHDNNPRTIQHIMGVIQGSTAKAVVVFAPSSFLIPLMNEVVLQNMTGRQWIASEAWATSLESHIPSFQPFLRGTIGIAIRRGEIQRLHDFLLRIRPSNDPKNYMLRIFWENMFGCSFGKGDTEGEQVIKVCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHALHDLMECEEGKGPFSKNSCADKTNLKPWQVVHYLQNVNFTTGFGDYVSFDKNGDALAIYDVLNWQPSSDESIRIYTVGVVKEGTETGMVLTLDEDAIFWNFETRKPPRSVCSESCPPGTRRATRKGLPVCCFDCLPCGDGEISNTTNAVECFLCPDEFWSNQYNNHCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVIFVFALHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHVVFGISFVLCMSSILVKTMVVIAVFKSSRPEGKGAIKWFGAVQQRSTVVVLTVLQVLICAVWLSTASPTPYKNNQYIRSKIVYECAIGSVVGFSMLLSYIGFLAAASFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFVPAYVSSPGKYTVAVEIFAILASTFGLLIAIFAPKCYIILLHPERNTKNVIMGRETQNK", "length": 829 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q166-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWSPLIICLYLSYNFKSAASILMGSCQLQGHFGLNGMYQAGDVILGGLFEVHLLAVFPELSFRSAPEPPYCEQFDMASFQQAQTMVFAIDEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLVSGTEELFSNLNCTGSPPVIGIVGDSNSTPSIAISSVLGLFRVPIVSYFATCSCLSNRKQYPSFFRTIPSDAFQVRAMVNILKHFGWTWVGLIYSDDDYGNYAAQSFLQDIQIYGGCVAFTEILPLNNNRKYIEHVVGVIQASTARVVVVFSTSTYVLPLMDEVVLQNVTNRQWIASEAWATSPMFHTQRLLPFLGGTLGIAIRRGEIQGLHEFLLHLRPKNDQHNNMVRIFWEKMFGCRFNPGGKGDKQCSGQEDLSSIDTAYTDVKELRASYNVYKTVYALAHALHDLTECDEERGPFSENRCADITNLQPWQLVHYLQKVNFTTGFGDHVSFDKNGDVLAIYDVMNWHPSSDGSISVRTVGVVNEGAASGKVLTLDEDAIYWNFKIKKAPQSVCSESCPPGTRQATKKGLPVCCFDCLPCGDGEISNVTNAIECTVCPDEFWSNKDKDQCVPKEVEFLSYEDPLGISLTTACLLGTCFCALVMIIFCQHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGSMKWFGTTQQRCTVLILTALQVVICIVWLSNSSPAPHKNSQHISSKIVYECAIGSLAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVTSPGKYAVAVEIFAILASSFGLLGAIFAPKCYIILLHPEKNTKKAIMGRQITK", "length": 860 }, "evidence": [ { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q1C5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNAHLLFTVKMLCIARLCIAVCGVDLGTCILQGDAQPPALSEDGDFIVGGAFTIHYYVRTEKYTYTRRPQPLECSGSMDFRELRFARALQFAIQEINNSSDLLPGIFLGYHIYDSCGSVPMAIKVALQLANGLDPKYNDTDSCAKSAAVLALVGDSASTPAISISRIFGPFEIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEKEGICVEYSEAYYRTYPLSKLKRVADVIRRSTARVIVAFVAAGDMRFLLEELSKEPLPPMQWIGSEAWVSDPQMLRFNLSIGTMGVAVPRSLIPGFRKFLLDLSPYKVLKFPLLTEFWESSFSCSLQQQTDPSTGMPACDGTEDLGRLKNPYTDTSQLRVSNMVYKATYAIAHALHGIVCNETQCSKNIKVKPRQVFDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPEGQEFSLNKAIIWYDGSEKVPVSVCSENCPPGTRKAVKKGRPVCCYDCIPCGEGEISNKTDSPDCDKCPPDYWPSTEKDKCLPKPVEFLSWDEILGIILAVLSVSGSLLALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWVVLGYIGLLASLCFVLAFLARKLPDNFNEAKFITFSMLIFSAVWITFIPAYVSSPGKFTVAVEIFAILASSFSLILCIFAPKFFIILFRPEENTKKHLMGKVQSKSY", "length": 856 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "RGD:11359049", "url": "https://alliancegenome.org/gene/RGD:11359049#orthology", "database": "AGR" }, { "id": "RGD:1597414", "url": "https://alliancegenome.org/gene/RGD:1597414#orthology", "database": "AGR" }, { "id": "RGD:6500225", "url": "https://alliancegenome.org/gene/RGD:6500225#orthology", "database": "AGR" }, { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "RGD:11482623", "url": "https://alliancegenome.org/gene/RGD:11482623#orthology", "database": "AGR" }, { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "RGD:1593384", "url": "https://alliancegenome.org/gene/RGD:1593384#orthology", "database": "AGR" }, { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1596944", "url": "https://alliancegenome.org/gene/RGD:1596944#orthology", "database": "AGR" }, { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1560816", "url": "https://alliancegenome.org/gene/RGD:1560816#orthology", "database": "AGR" }, { "id": "RGD:1592277", "url": "https://alliancegenome.org/gene/RGD:1592277#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RHU5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCCYICVTLIASTGTCQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMTSFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTSRQWIASEAWVTAAVFRTPYFQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTTNTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEGSIKLHNIGVVNEVATGMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTSRAMRKGFPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDRCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AUZ8-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcv3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHSLETMTILLLWLLVYHLSVLNPAQASKCLLQNEFEPGLMANGDFVIGGIFPLHYNQEMPDLNFTYKPGPVKCNGFDTRAFRWAITMKLAVEEINKRVDLLPNYTLGYKIFDSCAYPLTGQRSAVAVLNGPNELESPLCADAAPLLAVIGESGSAQSIVVSRILQPFGIPMISYFSSCACLSDRREFPTFFRVIPSDAYQVKAIAKLLRHFNWTWIGVIRGDHEYGRFALQGLLKELEGTGICVAYQKMIPLLYDRQKALEIIHVMSHSTARVVVVFSAEGELTPFLRDYMEQNVTGIQWIASEAWVTSSVFAGSEFDPFLGGTIGFGIRQGQIPRLKEYLTTVNPERYPTNPLVYELWGALYGCSPSWSNLSSHLPSCTGKETVRLQYSAYLNTSSPRISYNVYKAAYAIAYSLHNLIYCTPGKGPFSNSTCANAPHIYPWQLQQYLQEVSFTISGEKVNFDMKGDSIPSYDLINWQRGSAGNIEFINVGMFDGALESGQELVIKEEAIMWPGHQTEVLVSVCSNSCAPGFRKAVRRGQPLCCFDCVPCDSGKISNETDSLDCIACSEDYWSNADGTVCIPKVVEFLSHDAMGLTLTVIAVAGACLTLAVFSVFLYYKNTPVVRINNSELSFFILLSLTLCFLCALIFIGEPTSWSCMLRHTAFSITFSLCISCILGKTLVVLAAFTATRPGNNLMKWLGPTQQRIIIFCCTLIQVLICTVWLVASPPFPYRNTKYQQSKIILDCSVGSDLAFWCVLGYIGLLACVCFFLAFLARKLPGNFNEAKYITFSMIIFCAVWLAFVPAYVSSPGKFTTAVEIFAILASSFGLLLCLFTPKVYIILVKPEKNTKQHLMGKDK", "length": 859 }, "evidence": [ { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AV03-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYNNVLLIVTLQCIITRLYVVYGNRLGSCILQGDPQPPVLFDEGDFIIGGAFSIHYYLRTEKHTYTMRPQSLECSGSMDFRELRFARVLQFAIQEINNSSDLLPGITLGYRIYDSCGSVPMAVKLSFQLANGLDLIFNDNDSCSKSAAVAALVGESGSTPSISISRLYGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEEEGICVEYSEAYYRTQPRSKLMRVADVIRRSTARVIVAFMASGDMRLLLEELSQQPLPPMQWIGSEAWFTDPEMLRFNMCIGGVGFAIPRSVIPGFRTFLLDLSPQRAMKFPLLTEFWESSFSCSLKQQTGPSTGMPACDGTEDLGRLKNPYTDTSQLRISNMVYKATYAIAHALHGIICNEKKCNKNIKIEPREVLDKLKQVKFSKNNYSVSFDAYGDPVAVYELVNWQLQKDGSIDFVTVGKYDSSQPKGKEFSLSRAIIWYDGTEEVPVSVCSESCPPGTRKAVQKGRPVCCYDCINCADGEISNDTDCLDCHECLSDYWPNNEKNKCLRKPVEFLSWDEILGIILAAFSVAGSLVALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPSQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFGLILCIFAPKFFIIIFRPERNTKKHIMGKVPSKAL", "length": 856 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "RGD:11359049", "url": "https://alliancegenome.org/gene/RGD:11359049#orthology", "database": "AGR" }, { "id": "RGD:1597414", "url": "https://alliancegenome.org/gene/RGD:1597414#orthology", "database": "AGR" }, { "id": "RGD:6500225", "url": "https://alliancegenome.org/gene/RGD:6500225#orthology", "database": "AGR" }, { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "RGD:11482623", "url": "https://alliancegenome.org/gene/RGD:11482623#orthology", "database": "AGR" }, { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "RGD:1593384", "url": "https://alliancegenome.org/gene/RGD:1593384#orthology", "database": "AGR" }, { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1596944", "url": "https://alliancegenome.org/gene/RGD:1596944#orthology", "database": "AGR" }, { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1560816", "url": "https://alliancegenome.org/gene/RGD:1560816#orthology", "database": "AGR" }, { "id": "RGD:1592277", "url": "https://alliancegenome.org/gene/RGD:1592277#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B2Z8-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcg8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLFLYSVLSLYHLNTKAENTLCQMIGNPKYPLLSKDGDITIGALFVIHSEVSLPSFAFTQKPNLLSCSSLNIKDFRLAQTMIFAIEEINKNTNLLPNISVGYQIYDTCGSRFHSMSATMALMNGPKNSEGYTCNEQSSVHAIVGETESSNTIILSRTTGPFKIPVISPTATCECLSNRKEFPSFFRTIASDYHQSRALAYIVKHFGWTWVGAVNSDNDYGNNGMATFQKTAKEVQICVEYSVKFIRTETEKIRNVVNVIKKGTAKVIVAFLTGFEMKSLLEQLSSQNITGLQMIGVEAWITSKTLITSKSFHVLGGSLGFAVRKIQIEGFADYVMKAFWDTAFQSFSNADLNYSQYQDLLLVKNYNEDVLEQRFVSYVYKAVYALAHSLHSLLRCTEQGGCGKALTIQPHQLVEALRKVNFTVKMGDQVWFDSTGGVIAQYDVVNWQQNSDGSVQFQSVGYYDASLSPDQRFMLNTEKIVWAGGQLEKPRSVCSESCPPGTRKASQKGRPVCCHDCIPCADGEISNETDSNNCKQCPGEYWSNANKNKCVTKAVEFLSFTEVMGIILVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSIPFIGRPTQWSCMLRHTAFGITFVLCISCILGKTIVVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTLIQGLICVIWLTKSPPFPYKNMKYFQEQIILECSVGSTIGFWAVLGYIGLLAVLCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKLTVAVEIFAILASSFGLLFCIFAPKCYIILLQPEQNTKQQMMAKTPSKI", "length": 832 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "RGD:11359049", "url": "https://alliancegenome.org/gene/RGD:11359049#orthology", "database": "AGR" }, { "id": "RGD:1597414", "url": "https://alliancegenome.org/gene/RGD:1597414#orthology", "database": "AGR" }, { "id": "RGD:6500225", "url": "https://alliancegenome.org/gene/RGD:6500225#orthology", "database": "AGR" }, { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "RGD:1593384", "url": "https://alliancegenome.org/gene/RGD:1593384#orthology", "database": "AGR" }, { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1596944", "url": "https://alliancegenome.org/gene/RGD:1596944#orthology", "database": "AGR" }, { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PAH3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTKKSELLLLMVLVTHGICVPNLAQVCRLLGQPALPLLSEERNINIGAIFSLHKSALLKSHNFTSKPKQTTCGGLNLREFKFVQTLIFAIEEINNSSLLPGASLGYKIYDSCGSVAQAIFSGMALMNGYEETLSDTSCSTPPAVHAIVGESNSSPTIGLASVVGPFSLPLVSHFATCSCLSNRKRFRTFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGIATFEEAAKQEGICIEYSEAVFKTDPEVQFLKTIEVIKKATTKVVVAFMAFGDFVLLLKVMAQQNITGIQWIGSESWITSRNLAETKEYHFLSGAVGFAIANSKPVGLREFLMNVHPDKELNNELLKEFWETVFLCSFRNSSSGGCTGSEKLSELQNEYTDFSELRIENKVYTAVYAVAHSLHNVLKGFKFFTNSSKKQLPTPQKVLEYLRDVNFTVNTNENIFFDASGDPVARYDLVNWQPTKDGSLQFKLVGIYDSSLPSEQRLQINQESMLWAGNSGQLPVSVCSESCPPGTRKAVQKGRPICCYDCIPCAEGEISNYTDSSDCFPCGLEYWSNESKDRCVLKVIEFLSYTEIMGVGLCIFSFIGVLLTATVSFLFYFYKETPIVRANNSELSFLLLFSLTLCFLCSLTFIGRPTDWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLIQVIICVLWLTMSPPFPFLNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFFARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSAPGKYTVAVQLFAILASSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKS", "length": 849 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PD42-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWITLCIYLYLSLNYICAHSILRTSDSCRLQRRFHLNGMYKDGDVILGGLFQVHFFTVFPEQSFRTEPEPPFCEKFDMESFQQAQTMAFAIEEINKNPNLLPNITLGFHLYDNCVRLGMAFRAAISLASGTEESFQNLNCTGPPPVIGIVGDPSSTPSIAISSLLGLFRVPIVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLIYSDDDYGVYAAQSFHLEMQMFGHCVAFSEILPHNNNQRDIQRIMGVIQASTARVVVVFSTSSFLLPLIDEVASQNMTGRQWIASEAWATSPVYHSPRLLPFLGGTLGIAVRHGEIPGLHDFLLHLGPGNESRNNMLRIFWENMFGCSFEPGVKDTNSEIKLCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHGLHDLMQCEKGRGPFRGESCADITNLKPWQLVHYLQKVNFTTGFGDHVSFDENGDALAIYDVLNWQPSSDGSIQIFTVGVVKERTETGMVLTIDEDAIYWNFETKKSPQSVCSESCSPGTRRATRKGLPVCCFDCLPCRDGEISNTTDAIECMLCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGSCFCVLVMIIFGLHRNTPIVRANNSELSFMLLLSLKMCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGAMKWFGAAQQRCTVLVLTVLQVVICSVWLSTASPTPYKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKNAIMGRETQKR", "length": 867 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPM0-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcg12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVFFCTLLIFFQLYAKAEKPICIMMGDPKYPLLSKEGDISIGAVFPVHSIETLPLFKFTQKPQLLSCSSVSIRDFRMAQIMAFAIEEINRNESLLPNVSLGYQIYDTCGSGLSLMGANMALMNVQEFASRGSCNGQSPVHAIIGETESSNTVILSRTTGPFKIPVISPSASCECLSNRKEYPYFFRTIASDYHQSRALAYIIKYFGWSWVGAVNSDNDYGNHGMAIFLSTAEKEGVCVEYSVKFQRTEPEKLKKVVDTIKKGTSKVIVAFLTEFEMKNLLEYLIIQNVTGLQVIGVEAWITANSMIKPNSFHVLGGSLGFAVKKLNIEGFEDYVTKAFWETAFPCSQTSQKENSQYKLICNIYRDLLVLKNDNKDVPEQRYASNVYKAVYAVAHSLHNILKCRENGACETDMKIQPQQVVEALRKVNFTIKMGDCVWFDSTGAVVAQYEVVNWQPDYNGSIQFKPVGYYDASLPPNQRFVINTENIIWAGGQLKKPRSVCSENCPPGTRKAVQKGRPVCCYDCIPCAEGEISNETDSNNCKQCPGEYWSNAEKNKCVLKAVEFLSFKELMGIVLVFFSLLGAGLTTLVAILFYSKKDTPIVKANNSELSFLLLFSLMLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSDVMKWFGPIQQRLSVLVITIVQVLICVLWLAVSPPLPYKNTKYFKEKIILECSLGSTIGFSAALGYIGLLAILCFILAFLARTLPDKFNEAKFITFSMIIFCAVWITFIPSYLSSPGKLTVAVEIFAILASSFGLLFCIFLPKCYIIMCKPEQNTKLHIIGKLNK", "length": 837 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "RGD:11359049", "url": "https://alliancegenome.org/gene/RGD:11359049#orthology", "database": "AGR" }, { "id": "RGD:1597414", "url": "https://alliancegenome.org/gene/RGD:1597414#orthology", "database": "AGR" }, { "id": "RGD:6500225", "url": "https://alliancegenome.org/gene/RGD:6500225#orthology", "database": "AGR" }, { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "RGD:11482623", "url": "https://alliancegenome.org/gene/RGD:11482623#orthology", "database": "AGR" }, { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "RGD:1593384", "url": "https://alliancegenome.org/gene/RGD:1593384#orthology", "database": "AGR" }, { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1596944", "url": "https://alliancegenome.org/gene/RGD:1596944#orthology", "database": "AGR" }, { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2U8-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLCEMWITLNICLYMYFNHISGVFTSESCQLQGCFKLNGMYQDGEFIIGGLFEVQNLKVFPELSFTNEPELPQCEEFYMASFQQALTMVFAINEINSNSKLLPNITLGYQIYDNCLRLGVAFRAAMSLVSGTEESSNLSCTGPPPVIGIVGDPGSTQSITISSVLGLYRVPMVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLLYSNDDYGIYAAQSFQQEMQILGGCVAFSEMLPYDNNGRDIQRIAGVIQKSTAKVVVAFSTDLASLMDELLLQNVTGKQWIASEAWTTTPVLQTPQYLPLLGGTLGIAIRRGQIQGLYEFLKNLRPDKNPKNSTIRIFWETMFGCKFEVGGKKVDEQQERGRNKCSGQEDLNNSETAYTDVSELRASYNVYKAVYALAHALHDLVKCEEGKGPFTGNSCADISNLKPWQLVHYIQNVKFTTGFGDHVSFDENGDALAIYDVMNWHPRSDGSIIVHVVGVYEEAILGKVLTLDEDALFWNFETKKPPDSVCSESCPPGTRRARKKGLPVCCFDCLPCGDGEISNTTDSPECFICPEDFWSSPENDRCVPKEMEFLSYDDPLGISLTTASLLGTCFCVLVLVIFAYHHNTPVVRANNSELSFLLLVSLKFCFLCVLLFIGRPRLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKTSRPEGKTSIKWFGSAQQRGTVIALTSAQVAICTVWLSSASPTPHKNNQYIHSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFMARKLPDNFNEAKFITFSMLIFCAVWIAFVPAYASSPGKYAVAVEIFAILASSFGLLAAIFAPKCYIIILHPERNTKKAIMGRSTQNK", "length": 868 }, "evidence": [ { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2V5-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcx2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALLCATLLMVWFLMYLSVQSQYNSKVRCVFQGDDDTNTFYQGGDVVLGGLFPLHFSPISSLSSYKTKPTPTTYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPDKDSGQSCEDTRKQPSPVVVGEASSGISMAVLRSLGCFKIPLVSYFASCSCLSNKKEFPAFMRTMPSDLFQIKALAKLVHYFQWTWVGVIGVDTDYARFAIQLFLKESQQLNICLAYVQLYPVALNQDSAEELVRMLKSSSATVIISFSVDSYLYGILKECRRQNVTHLQWIASEAWATSKSLWEEFGDLLKGTLGFAIHRADIPHLGSYLKEIRPQTSHFLSEFWEETFRCRLNGSLNTHAHGEQAQNWPACNGSESLDDVYTTYSDVSQLRVSYNVYKAVYLIAHALHDMSTCVPGKGPFQNGTCGSLFQIQPWQLLYYMKQTNFTTLGEEIRFDENGDPIASYDLMNWQRGSDSSLQLVRVGFYDASLEDDKDLVIDESLIMWHRAEKAPESLCSKSCLPGSRKARQKGKPVCCFDCISCAEGEISNHTDSIECLTCSEDTWPNQSQDQCIPKTLEFLSFQEPLGIILWVFSAFGACAALAVLCVFVMYRKTPVVRGNNIELSFLLLLFLCACFLIGLTFLGKPTDWLCQIRYPAFGISFTLCISCILAKTVVVLMAFRATIPGNNVMKWFGPVKQRSSVILCTCVQALICIIWLTTKPPLASYNSKFMSETIIVECSVGSEIGFWCVLGYVGLLACLCFLMAFLARKLPDNFNEAKFITFSMLIFFAVWITFIPVYLSSSGKYMVAVHVFAILASAFGLLLCIFFPKCYIVLLKPEKNDKKHIMKK", "length": 863 }, "evidence": [ { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T5D2-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCYYICVTLMASTGICQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMESFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLHNLTSRQWIASEAWVTAAVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTANTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEESIKLHNIGVVNEVATEMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTRRAMRKGLPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDQCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSLAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6G6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAILLFCLFLSCNFICVTLMVSSGTCQKQGHFTLNGMHQDGDFVIGGLFEIQSYVKVYPEISFRTQPKLPNCDLFYMTSFQQALTMVFAISEINNNPNLLPNITLGYQIYDNCLRLGVAFRAATALISGTEETISDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRLPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAMVQTMRHFGWTWVGLIYSNNDYGIYAAQSFHKEMQLFGHCVAFSEILPQDNNPRVIDHIIGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTGRQWIASEAWVTSTVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETEDKETFGQQIKKVCTGQEDLSITNTPYTDVSGLRAPYNVYKAVYALAHALHDLMQCKEKRGPLSEKNCADITDLKPWQLLSYLKKVNFTTGFGDPVSFDNNGDALAIYDVLNWQPSSEGSIKLHSIGVVNDEVATGMVLRLNKDEIYWNFEAQKAPRSVCSESCPPGTRKAMRKGFPVCCFDCLTCGDGEISNTTDAIKCTVCPDEFWSNFNKDQCVPKEIEFLSYEDPLGISLTTASLLGTCFCALVMIIFAFHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFNSSRPEGKGAMQWFGAAQQRCTVLVLTVLQVVICAVWLSTSSPTPHKNNQYVRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRETKKY", "length": 869 }, "evidence": [ { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6Z6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcq17", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLYLSLCLCFKHIYADSIHRLRSCQLQGRFKLNGMYQDGDFILGGLFHVHFFTVFPELSFRMEPQQPYCEKFNMEGLQHAQTMAFAINEINKNPTLLPNITLGYHLYDNCVMLRMAFRAAMSLASGTEDSYSNLNCTGPPPVIGIVGDASSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKHFKWTWVGLLYSGDDYGVYAAQMFHKEMQLSGHCVAFSEILPNDHNPKDIQRIIRVIQGSTARVVVVFALSSFLIPLMDEVVLQNMTGCQWIASEAWATSLEYHTPRFLPFLGGTLGIAIRRGEIEGLHEFLLRIRPSNDTSQNIVRIFWENLFGCRFETGGLKTGREQEKMECTGQEDLSTTNTPYTDVSGLRASYNVYKAVYALAHGLHDLMQCEEGRGPFIGNSCADITSLKPWQLVHYLQNVNFTTGFGDHVTFDKNGDALAIYDVLNWQPSSDGSITVHKIGVVYEGATTGMMLTLDADAIYWNFETKKPPLSVCSESCPPGTRQATRKGLPLCCFDCLPCGDGEFSNTRDAVECMMCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGAMKWFGASQQRCTVLVLTALQVVICAVWLSTASPTPHKNNHYFRSIIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFALLLAIFAPKCYIILLHPERNTKNAIMGRETQNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TDV0-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfck1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRISLGWVVCLVKEMHVNLLLILTLLCIRRLFPAVCGVHLGTCILQGDPQPPSLFSKGDFVIGGTFTIHYYLRTEKRTYTVRPQPLMCSGSMDFRELRFARVLQFAIQEINNSSNLLPGITLGYHIYDSCASVPMVIKVAVQLANGLQLAFNDTDSCAQSSEVLALVGESGSTAAITTSRLFGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEVEGICVEYSEAYYRTQTRNKLQRVADVIRRSTARVIVAFMAAGDMRFLLEELSQQPPPPMQWIGSEAWVTDPQMLRFNLSIGAVGFAIPRSVIPGFRKFLLDLSSEQALKIPVLKEFWESSFGCSLKQHTGYFSGMPACDGTEDLGTLKNPYTDTSQLRISNMVYKATYAIAHALHGIVCNGKLCDKNIKVEPRKVSDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPKGQEFSLNRAIIWYDGTEKVPVSVCSESCPPGTRKAVKKGRPVCCYDCINCADGEINNETDSLDCHKCQPDYWPNAEKIKCLPKPVEFLSWDEILGNTLAAFSIAGSLVALSMALVFYKNRVSPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFSLILLIFAPKCFVIVFRPEENTKRHLLGKVPPKAL", "length": 870 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "RGD:11359049", "url": "https://alliancegenome.org/gene/RGD:11359049#orthology", "database": "AGR" }, { "id": "RGD:1597414", "url": "https://alliancegenome.org/gene/RGD:1597414#orthology", "database": "AGR" }, { "id": "RGD:6500225", "url": "https://alliancegenome.org/gene/RGD:6500225#orthology", "database": "AGR" }, { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "RGD:11482623", "url": "https://alliancegenome.org/gene/RGD:11482623#orthology", "database": "AGR" }, { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "RGD:1593384", "url": "https://alliancegenome.org/gene/RGD:1593384#orthology", "database": "AGR" }, { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1596944", "url": "https://alliancegenome.org/gene/RGD:1596944#orthology", "database": "AGR" }, { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1560816", "url": "https://alliancegenome.org/gene/RGD:1560816#orthology", "database": "AGR" }, { "id": "RGD:1592277", "url": "https://alliancegenome.org/gene/RGD:1592277#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUY1-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWVILHIYFFISCNYMSVALMASSGTCQLQGHFTLNGMYQNGDFLIGGLFEIQYLKAFPGLSFRTEPKLPHCENFYMTSFQQAITMVFAINEINNNPNLLPNITLGYQMYDNCLRLGVAFRAATALISGTEETLSDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMIQILRHFEWTWVGLLYSDDDYGINAALSFHHDVQQFGGCVAFSEILPNDNNQMAVQHIVRVIQNSTAKVVVVFSTSSYLLPVIDEMLLKNITGRQWIASEAWSTSPVLLNPRLRYVLGGTLGIAIRRGEIEGLDNFLLRLRPDNFSQNSMMRIFWENMFECNFDTIGGLRTKLCSGQEDLRSKFTPYTDVSELRASYNVYKAVYALAHALHDLMHCEEGRGPFSENRCVDISNLKPWQLVHYLQRVKFTTGFGDHVSFDKNGDALAIYDVLNWQLSSEESVTVRRIGVVDEGVTTGKVFTLDENAIYWNFETNKPPRSVCSESCPPGTRQATRKGLPVCCFDCLPCGDGEISNTTDTTECIACPNDFWSNPEKDQCIPKEVEFLSYEDPLGISLTTAAMLGTFICALVMTIFAHYRNTPVVRSNNSELSFLLLLSLKLSFLCVLLFIGQPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKNAMKWFGAAQQRGTVLILTALQVLICAVWLSTASPTPHKNSRYIRSIIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDSFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIIILHPERNTKKAIMGKGTKNK", "length": 863 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UVL1-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLTWHRLFIKATPSKVFIINNIHRGELKRNVEMWIIAKICLYLSFSCISVASIFRSGPCQLQGQFRLNGMFQEGDLILGGLFEVHFLTVFPEQSFRTEPEPPYCEQFDMASFQQAQTMVFAIDEINRNPNLLPNITLGYYLYDNCVKLSVAFRAAMALVSGTEESFSSLNCTGPPPVIAIVGDPGSTHSIAISSILGLFRVPMVSYFATCSCLSDRKTYPSFFRTIPSDAFQVRAMVQILKRFGWTWVGLLYSDDDYGIYAAQSFQKEMQLFGACVGFSEMLPRDNNHEDIQSIVEVIQTSTARVVVVFSTEAYLLPLMDEVALKNVTGRQWIASEAWATSPVFHTQHLLPFLGGTLGIAIRRGEIQGLKEFLYYLHPDSNTRNNIVRIFWENIFGCSFEIGGRERKVCTGQEDLKSTNTAYTDVSGLRASYNAYKAVYALAHALHDLMQCEDGRGPFSGNKCADQINLQPWQVVHYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWQPSSDGAISVSTVGVVNEGASMKMVLTLKENSIFWNFKNRKPPQSVCSESCPPGTRQVRRKGLPVCCFDCLPCADGEISNTTDAIECKICPDELWPNPNKDQCVPKEEDFLSFEDPLGISLTTASLLGTCFCALVMVIFSHHRNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPKLWTCQLRHAAFGISFVLCVSSILVKTMVVIAVFKSSRPESKSAMKWFGVAQQRGTVMALTTLQIVICTVWLSMASPKPYKNSLYISSKVVYECDIGSVVGFSLLLGYIGLLAAVSFLFAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYMILFHPERNTKKSIMGRATQIK", "length": 894 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V5L1A2-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSVSMWGYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFSQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSHQSLGKIEETVQKMQKCTSKVVLVFLSNSNFQLILHGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVPSSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPSWLKQGHHI", "length": 845 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AB13A3P1-1", "protein_name": "Olfactory receptor CG7", "gene_name": "olfcg7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSANSLFMVSLTFRMILYFYTILFLRCFQAKTENAFCQIIGEAKYPLLSKDGDVTIGGIFAIHSKETLPSFEFQQKPQPLLCSSVNLRDFRLAQIMIFAIEEINKSENLLPNVSIGYRIFDTCGSRLSSMSATMGLMNELKFAAGETCNGQSPIHAIIGETESSATVILSRTTGPFKIPVISHSASCECLSNRNDYPSFFRTISSDYHQGRALAYIVKYLGWSWVGAVNSDNDYGNYGMAIFLETAQKEGICVEYSVKFYRTETEKLKRVVDTIKKSTAKVIVAFVSFIEMGLLIEQLSIQNITGFQIIGVEGWITSKNYITTNSFHSMGGSLGLALRKIHLEGFLDYVTKSFWSTAFPCSQTEGILPTVGCSKYKDLLPLKNYTEDVPEHRYSSHVYKAIYAVAHSLHSLLKCKEGEDCEKGHATQPQQVVEALKKVNFTVKFGDRVWFDRTGATVAHYEVVNWQQDTDGSFQFKQVGYYDASLPPDQRFVLNIESIIWPGGNLEKPRSVCSESCSPGTRKAAQKGRPVCCYDCVPCADGEISNETDSVNCKQCPREYWSNGEKNKCVLKAIEFLSFTEIMGIVLVCFSLFGVGLTAVVAILFWSKMDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMVFKATLPGSNVMKWFGPTQQRLSVLAFTFIQVLICVLWLTISPPFPNKNMTYYKEKIIIECSLGSTISFWAVLGYIGLLAVLCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSFGLLLCIFAPKCYIIICKPEQNTKQHVMGKTSLKVQ", "length": 851 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TCB3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNFGAGLRTGSRNGNEKWKRMTFCRSSAFCHMFSSTLYLISSMARHAVVLRAGACQLQGRFRLNGMYQDGDVILGGLFEAHFFTLFPELTFRTEPAPPYCEIFNMESFQYAQTMAFAINEINRNPSLLPNISLGYHLYDNCVMLGMALRAAMSLVSGIEESFLNLNCTGPPPIIGVVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMIQLISHFGWTWIGLLYSDDDYGTYAAQSFHQEMQLFGFCIAFSEPLRYDSNPRDIQRLMEVIQASTSTVVVVFSPSTLVIPLMNEVVLQNMTGRQWIASESWATSPVFYTPRFLPFLGGTLGIAIRRGEIEGLREFLLQLRPKNDPRNNMLKIFWENMFGCSFETGPHVKNVCTGQEDLSTTNTPYTDVSELRAANNVYKAVYALAHALHDLMKCEEGKGPFSKNSCAEISNLKPWQLVHYLQKVNFSTRFGDHVSFNKNGDALAIYDVMNWQPGSDRSIRIHTVGVVSEELEKGLMLTLDEDAIYWNFETKKPPQSVCSESCPRGSRRATRKGHPVCCFDCLPCRDGEISNTTDATKCTVCPDDFWSNLYKDQCIPKEVEFLSYNDPLGISLTTASLLGTCFCAFVMVIFVHHHNTPIVRANNSELSFLLLFSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKMAMKWFGAAQQRCTILALTAIQVVICVVWLSTASPTPHKNNLYIRSIIVYECTIGSVTGFSMLLGYIGLLAAVSFLIAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYSVAVEIFAILASSFGLLVSIFAPKCYIILLHPERNNKKAIMGRETH", "length": 888 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LAY5-1", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "Vom2r5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTIAIFSLKFCLILCSLTEPNCFWRIKSSEDNDGDLRSDCGFVLFTHEGPIPEDFYNDIINFRIPARKYEFFLVLLFATDEINKNPYLLPNMSLIFNIIFGLCEDTLGVLDKAYLHQNSNSELFNYYCGINQLCDVDLTGPSWTTSLKLSIYSRTPKIFFGSFNPNLSDHDQFPYIYQIAAKDTYLFHGMVSLMFHFGWTWIGLVISDDDQGIQFLSDLREEMQRHAICLAFVNMIPETMQIYKTRVKIYDQQLMTSSAKVVIIYGEVNSTLELSFRRWAYLGAQRIWITTSQWDVITHKKDFSLDFSHGTVTFAHHHNDIAVFRNFMQTINTSMYPVDISQSMLQWNHFNCSISKNKKKMDCFTFKNPLEWLIQHTFDMVLSEEGYNLYNAVYAVAHTYHKLIFQQVESQKMEEPKGLFTDCQQVTSLLKTIEFTNPVGELVDTKHKENQCATYDIFITWNFPQGLGLKVKIGSYFPCLPQSQQLHISEDWEWVTGETLIPPSVCSMTCTAGFRKIHQKETADCCFDCVQCQENEIANDTADMEQCVKCPDDSYANLEQSQCLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLYIGHPNQATCILQQTTFAIFFTVAISTVLAKTITVVTAFKLTTPERRIKKIMIKGAINLLIPICTLIQLVLCAVWLVISPPFIDRDIQSEHGKVIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKDMVIVEVFSILASSAGLLGCIFFQKCYVLLVRPDLNVLRK", "length": 842 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LDN1-1", "protein_name": "Vomeronasal 2 receptor, 1", "gene_name": "Vom2r1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTIAFFPLKFCLILCSLTEPNCFWRIKKIEVYDGDLQNDCGFVLFTLESPIEENFYNHIINFRIPARKYEFFLVMFFATDEINKNPYLLSNMSLIFSFIFGMCEDTMGVLDKAYLHQNNYFDLLNYNCGRKKRCDVKLTGPSWKTSLKLSVNSRAPKIFFGPFNPNLSDHDQFPYIYQIATKDTYLLHGMVSLMFHFEWTWIGLIITDDDQGIQFHSDLREEMQRHAICLAFVIMIPESIKLYNTKFKIYDQQLMTSSAKVTIIYGKMISTLELNFARWTYLVARRIWITTSKLDVITYDKDFSLDFFHGTVIFAHHHNDIATFRNFMQIINTSKYPVDISQSMGQWNHFNCSISKNKKKMDFFMLKNPMEWLTQHTFDMVLSEEGYNLYNAVYAVAHTYHELIFQQVESQEMAKPKGLFTDCQQVASLLKTRVFTNPVGELVNMNHKENQCAKYDIFIIWNFPNGLGLKVKIGSYFPCLQQSQHLHISEDWEWVTGETLVPSSVCSETCTAGFRKSHQKQTANCCFDCVQCQENEIANDTDMEQCVRCPDDSYANLEQTQCLQRAVTFLAYEDPLGMALGCMALSFSAITVLVLVTFVKYRDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQATFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRKMMIKVATHLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKVIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVIVEVFSILASSAGLLGCIFVQKCYVLLVRPDLNVLQK", "length": 841 }, "evidence": [ { "id": "RGD:1596944", "url": "https://alliancegenome.org/gene/RGD:1596944#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LKX1-1", "protein_name": "Vomeronasal 2 receptor, 4", "gene_name": "Vom2r4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKMWAFTIAFFSLKFCLILCSLTEPSCFWRIKRSEDNDGDLRSDCGFVLFTLESPIEENFYTRIINFRIPARKYEFFLVLFFAIDEINKNPYLLSNMSLIFSIIVGLCEDTMGVLDKAYSHQSKIFKRINYFCGIKQRCDINLTGPSWTTSLKLSIYSRTPKIFFGSFNPNLSDHDQFPYIYQRANKDTYLFCGMVSLMFHFGWTWIGLVISNDDQGIQFLSDLREEMQRHAICLAFVIMIPETMQIYKTRVKIYDQQLMTSSAKVVVIYGEMNSTLELSFRRWAYLGAQRIWITTSQWDVITNQKDFSLDFSHGTVTFAHHHNDITIFRNFMQTINTSKYPIDISQSMLQWNHFNCSISKNKKKMDCFTFNNPLEWLVQHTFDMVLSEEGYNLYNAVYAVAHTYHELIFQQAESQKMADPKGVFTDCQQVASLLKTRVFINPVGELVNMNHKENYCAKYDIFIIWYFPQGLGLKVKIGSYFPCLPQSQQLHISEDWEWVTEETLVPSSVCSVTCTAGFRKIHQKQTADCCFDCVQCQENEIANDTDMEHCVRCPEDSYANLEQTECLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYRDTPIVKANNRILSYILLISLAFCFLCSLLFIGHPNQATCILQQTTFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRKMMIKGAINLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKIIIICNKGSVIAFHIVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVQKCYVLLVQPDLNVLQK", "length": 841 }, "evidence": [ { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LQR9-1", "protein_name": "Vomeronasal 2 receptor, 57", "gene_name": "Vom2r57", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADMEKAYTLIVFFLLLRLSFILCGFPEATCFWRINHNEHLESNMRKDCGFILFTIPVHLVEDHFRVLLDFPLPVNTYPYVLVMLFAIEEINRNPNLLPNSTLGFTVLGDQCDITSTNLNNLNMLSKSGEIIPNYICEYSDCDVALTGPTWTVSARVATLLQLFKIPQVMLNVTYGPFYDSLSDRDLFPHLYQIAPKDTSLVLAMVSLMIHFLWKWVGLVILDDDQGVQFLSDMKEEMKINDICLAFVNRIPANMQLYIERAGIYYFQIMTSSANVVIIYGNVNSTLEVSFRRWEMLGIWRLWITTSQWDVISRSRDFTIDSFHGTLSLSHHYREISTFKHFIQKTNFSAYPEAVSLVRLGWIYFNCSVSVSECKTLNHCLSNTILELLLWHSFDMAMNDERYNIYNAVYAVAHAFHNMHLQQVDIKVLESWKGLIPRCMQVNDFLKNIRFINPIGDPVTVNQGRNLDAMYDILNVLHFPQGYVLKVKVGQFSPYFAHDQQLLLSEDMIEWATGSRQFSTSVCSMPCHPGFKKSHPEGKADCCFDCLRCPANEISNTTDSEECVKCPEDWYADTEQTHCLPKAVTFLAYEDPLGMALVCLALCFSVLTALVLGVFLKHRETPIVKANNRTLSYILLTALIFCFLCSLLFVGNPNTTTCILQQTTFGILFTVSVSTVLAKTLTVVLAFRITLPGRRMRGLMVSRIPKYIIPICTVVQIILYGIWLWTSPPFVDIDTHSEHGCITITCSKGSVMAFYCVLGYLGSLALVSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSSKGKVMVAVEVFSILASSMGLLGCIFIPKCYIILLRPDRNSIQKFRDKTHS", "length": 859 }, "evidence": [ { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M0L6-1", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "LOC108348097", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADMEKAYTLIVFFLLLRLSFILCSFPEASCFWRINHNEHLESNMRKDCGFILFTIPVHLVEDYFRVLLDFPLPVNTYPYVLVMLFAIEEINKNPNLLPNSTLGFTFLGDQCDITSTNLNNLNMLSKSGEIIPNYICEYSDCDVALTGPTWTVSARVATLLQLFKIPQVMLNVTYGPFHDSLSDHDLFPHLYQIAPKDTSLVLAMVSLMIHFIWKWVGLVILDDDQGVQFLSDMKEEMKINEICLAFVNMIPANMQLYIERAETYYFQIMTSSAKVVIIYGNVNSTLEVSFRRWEMLGIWRLWITTSQWDVISRSRDFTIDSFHGTLSLSHHYREISTFKHFIQKTNFSAYPEAVSLVRLGWIYFNCSVSVSECKTLNHCLSNTILELLPWHSFDMAMNDERYNIYNAVYAVAHAFHNMHLQEVDIKVWESWEGLIPRCMQVNHFLKNVRFINPIGDPVNINQGRNLDAMYDILNVLHFPQGYVLKVKVGQLSPYFAHDQQLFLSEDMIEWATGSRQFSTSVCSMPCYPGFKKSHQEGKADCCFDCSRCPANEISNTTDSEECVKCPEDWYANTEQTHCLPKAVTFLAYEDPLGMALVCLALCFSVLTALVLGVFLKHRETPIVKANNRTLSYILLTALIFCFLCSLLFVGNPNTTTCILQQTTFGILFTVSVSTVLAKTLTVVLAFRITVPGRRMRGLMVSRISKYIIPICTVVQIILYGIWLWTSPPFVDIDTHSEHGCITITCSKGSVTAFYCVLGYLGSLALVSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSSKGKVMVAVEVFSILASSMGLLGCIFIPKCYIILLRPDRNSIQKFRDKTHS", "length": 859 }, "evidence": [ { "id": "RGD:11482623", "url": "https://alliancegenome.org/gene/RGD:11482623#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M8M8-1", "protein_name": "Vomeronasal 2 receptor, 72", "gene_name": "Vom2r72", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFPITFLILKFSLIYFHLTEPSCFWRIKNSEETDGDLRSDCGFVLLAFEEPIEENYYNELINFRIPATKYEFFLVMFFATDEINKNPDLLPNMSLIFNLVGRMCEDTLGLLDEIYSQENKTSYIINYVCGIELSCDIDLIGPSRTTSLKLAIHSMMPKVFFGPFNSNLIDHDQFPYIYQIAIKDTCLPHGMVSLMLQFGWTWVGLIISDNDQGIQFFSDLREEMQRHGICLAFVNVIPETMQRYSTRAKIYDKQLMTSSAKVVIIYGEMNSTLEVSFRRWAYLGVQRIWVTNSQWDVIINKRDFSLDFFHGTVTFAHHHSGMTIFRNVMQTMNTSKYPIDLSQSMLGWNYFNCSISENRHSKTDHFTFNNTLEWLALHKFDMVLSEEGYNLYNAVYAVAHTYHELISQNVESQKVAEPKGLFTDCQQVASLLKATVFTNPVGELVNMNHRENQCAEYDIFIIWNFPEGLGLKVKIASYFPCFPHNQQLHTSEDLEWATEGTLVPSSMCSATCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCARCPDDKYANSEQTYCLQRTVSFLAYEDPLGMALGCMALFFSAITILVLVTFVKYKDTPIVKANNCILSYILLISLIFCFLCSLLFIGHPNKATCILQQTTFGVFFTVAVSAVLAKTVTVVMAFKLTTPGRRMRGMLASGATNLVIPICTLIQLVLYGIWLAISPPFIDRDIQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSITVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDLNFLQK", "length": 843 }, "evidence": [ { "id": "RGD:1597414", "url": "https://alliancegenome.org/gene/RGD:1597414#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0T300-1", "protein_name": "Olfactory receptor CD2 precursor", "gene_name": "olfcd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANTLSLLLLLLLLHGHFLPATVQICDLVGQSALPVLSAERDINIGAIFSIHRNALLRLYPFTSKPEPTTCVRLNLREFKFAQTFIFAIEEINNNTQLLPGVTLGYKIYDACNAISPTLVSGMALINGYENTLSDTSCSQPPAVQAIVGESSSSPTTALAALVGPFNIPVISHFATCACLSNRKRYPSFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGITAFEDAAKQEGICIEYSEAILRTDPQEQFRKTVEVIKKGTSKVVVAFISFGDFAPLVKVIAENNITGLQWVGSESWITSRNLAETKEYSFLSGAVGFAIVNAKLVGLKEFLVNVHPDQEPKNKLLKEFWETAFQCSFSNSDSALCTGSEKLGELKNEYTDVSELRIEHKAYAAVYAVAHTLHNVFKDVKAPNNSKRELPTPQKVLQYMRNLSFTIKTGENIFFDASGDPVARYDLVNWQTAEDGSLQFKHVGIYDSSLPSKQRLQVNQEIMLWAGKSGLLPLSVCTESCLPGTRKAVQKGRPVCCYDCIPCAEGEISNSTDSSDCFSCDLEYWSNEKKDRCILKVVEFLSYAEIMGIILCIVSFIGLLLTVMVTCLFYLHKETPIVRANNSELSFLLLFSLSLCFLCSLTFIGRPTQWSCMLRHTAFGITFILCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLVQVIVCLLWLTLSPPYPYMNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSSPGKYTVAVEIFAILVSSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKL", "length": 848 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0T301-1", "protein_name": "Olfactory receptor CQ19 precursor", "gene_name": "olfcq19", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWVILNISIYLIFNFIMSASILGSNTCQLQGHFRLNEMYHDGDVILGGLFEVDFLTVFPDLDFKTEPEPPYCVQFDMESFQQAQTMAFAIDEINKNPNLLPNITLGYHLFDNCVMLGMAFRAAISMASGTEEFFNNINCTGPPPVIGIVGDSSSTVSIAISSILGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKYFRWTWVGLIYSDDDYGVYAAQSFQQEMQLFGGCVAFSEVLPHDNNLEDIKHITKMIQASTARVIVVFSTPSFLIPLIDELVLQNMTDRQWIASEAWATSFVHHSPRLLPFLKGTLGIAIRRGEIQGLYEFLLRLQPTNDPKNNMIRIFWEIMFGCNFETGGKKNSGDQVINICTGQEDLRTTKTPYTEVSELRASYNVYKAVYALAHALNDLMQCEDGRGPFSVNSCADITNLKPWQLVHYLQNVNFTTDFGDHVSFDKNGDALAIYDVLNWQPSSDGSIRAQTVGVVNEEVATGMVLTLDEDALYWNFESKKPPSSVCSESCAPGTRLATIKGLPVCCFDCLPCGDGEISNITGAVECTMCPDEFWSNLDKDQCIPKEVEFLSYEDPLGISLTTASLLGTCFCVLVMFVFAVHRNTPIVRANNSELSFLLLLSLKMCFLCALLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPESKGAMKWFGAVQQRCTVLVLTAIQVVICAVWLSTASPAPHKNNQYIRSKIVYECAIGSVAGFSMLLAYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIILLHPERNTKKAIMGKEAQNT", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2BE32-1", "protein_name": "Vomeronasal 2, receptor 121", "gene_name": "Vmn2r121", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLCAFTISFLFLKFSLILCCLSEPSCFWRIRNSEDSDGDLQRECHFYLWLIDESIEDNFVSDLNFRIAASEYELLLVIFFATDEINKNSYLLPNMTLMFSIIGGNCHDLLRSLDQEYTEIKGHMNFVNYFCYLDDSCAIGFTGPSWKTSLKLGLHSSMPLVFFGPFNPNLRDHDRLPHVHQVATKDTHLSHGMVSLMFHFRWTWIGLVISDDDQGIQFLSDLREESQRHEICLAFVNMIPENMQIYMTRATIYDKQIMTSSANVVIIYGEMNSTLEVSFRRWEELGAWRIWITTSQWDVIKNKKEFTFNLFHGTITFAHHKVEIPKFKKFMQTMNTAKYPVDISHTILEWNYFNCSISKNSSKMDHMTFNNTLEWTALHNYDMAMSDEGYNLYNAVYAAAHTYHEHILQQVESQKKAKPKRYFTACQQVSSLMKTRVFSNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYIPCFPKSQQLHICDDLEWAMGGTVPSSVCSVACTAGFRKIHQEETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANIEQTHCLSRAVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQVSCILQQTIFGVFFTVSVSTVLAKTITVVMAFKLTTPGRRIRGMMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTVILCNKGSVIAFHVVLGYLGSLALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSTRGRVMVVVEVFSILASSAGLLMCIFVPKCYVILIRPDSNFIKKHKGKLLN", "length": 847 }, "evidence": [ { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "RGD:1560816", "url": "https://alliancegenome.org/gene/RGD:1560816#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YWE3-1", "protein_name": "Vomeronasal 2, receptor 84", "gene_name": "Vmn2r84", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMCALTISFLLLKFSLILCCLKEPICFWRIKSSEYNDGNLQSECGYFVWTMKKLMKDDFYNVWLDFRIPASEYEFVLVMFFATNEINKNPDLLPNTSLVFSVMAGNCQDSLGNLDIQYMLTNDSLNYVNYVCDIDDSCAIGLTGPSWKTSLKLAIDSWTPTVFFGPFNPKLSDHDHFPYVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGVQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWAYLGARRIWITTSQWDVITNKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSVLRWNYFNCSVSKNSIKMDHFTCENPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILQQVESQKMAEDKGEYTECQQLAPLLKTRVFTNPVGEMVNMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTSVPSSMCSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETDMEQCVRCPDDQYANLEQTHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYRDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGGRMRGMMMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIDRDIQSEHGKTVIFCNTGSVLAFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYAILVRPDSNCIQKYKGKLLY", "length": 849 }, "evidence": [ { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "RGD:1560816", "url": "https://alliancegenome.org/gene/RGD:1560816#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZDW0-1", "protein_name": "Vomeronasal type-2 receptor 116-like", "gene_name": "LOC108348195", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLTLILLFFLLNIPLLVASFIYPRCFWSMKKNEYQDRNLGTGCMFFILAVQQPVKKEYFSHISNIQTLTENQKYPLALAFSMNEINNNPALLPNMSLVFQFSEYVCFLESQYKHLFSLDLQNHEILPNFICTEDIKCGVVLTGLSLVTTVTLHIILNNFIFKQFCHLTYGHFHPVLDDHENFPHLYQMASDDTSLALALISFIIHFSWNWVGLAISDNDQGTHFLSYLRREMEKNTVCFAFVNIIPVNMNLYMSRAELYYSQIMTSSANVVIIYGDTGNTLAVSFRMWDSLGIRRLWVTTSQWDVTPFKKDFTFDNGYGTFGFGHRHSEISGFKYFVQTLNPFKYSDEYLVKLEWMYVNCKILENKCKTLKNCSFNHSFEWLMTHTFDMAVIEGSYEIYNAVYAFAHALHEMTLPNVDNLLLDNYKEQYYNCKKVYSFLSKTQFTNPVGDTVNMNQRNKLKEEYDIFYNWNFPQGLGFKVKIGIFSPYFPKGQQLHLCENLIEWSTGSIQMPTSVCSADCGPGFRKVWKNGMPACCYDCSPCPENEISNETNVELCVQCPEDQYANQEQNHCIHKARIFLTYDEPLGMALSLMALCLAALTVVVLGIFVKHHRTPIVKANNCTLTYILLIALIFCFLCPLFFIGHPNSATCILQQITFGVVFTLAISTVLAKTTTVILAFRVTAPHRMMKYFLVSRASNYIIPICTLIQIIVCAIWLGASPPSVDIDAQSEHGHIIIVCNKGSITAFYCVLGYLACLAFVSFTLAFLSRNLPVTFNEAKSMTFSMLVFCSVWVTFLPVYHSTKGKVMVVVEIFSTLASSAGMLGCIFVPKCYTILCRPDRNSLQMIKEKSSSHTHIL", "length": 857 }, "evidence": [ { "id": "RGD:11359049", "url": "https://alliancegenome.org/gene/RGD:11359049#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ04-1", "protein_name": "Vomeronasal 2 receptor, 67", "gene_name": "Vom2r67", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTVAFLFLKFSVILCRTQLTEPNCFWRIKNSEDNDGDLQNDCGFILFTFKGRIEENFYNKLLNFINFRIPARKYEFFLVMFFATDEINKNPYLLSNMSLLFSIIFGMCEDTLGIVDEVYSQSNKGLAFTNFICGVESTCDIQLTGPFWTTSLKLAIYSKAPKLFFGPFNPNLNDHVQFPYVHQVASKDTCLSHGMASLMLHFKWTWIGLAISDDDQGIQFLSDLKEEMQRHGICLAFVNMIPENMQIYMTMAKIYDKQIMTSSAKVVVIYGKINSTLEVSFRRWGNLGAHRIWITTSQWDVITNIKDFNLDFFHGTVTFAHHHSDIAEFRNFMQTINTSKYPVDISQSMLGWNHFNCSISKNNSKIDYFTFNNPLEWLAQHTFDMVLSEEGYNLYNAVYAVAHTYHELILQQVESQKMEEPKGVFTDCQQVASLLKTRVFTNPLGELVNMNHRENQCIEHDIFIIWNFPQGLGLKVKIGTYFPYFTHNQQLHISEDLEWATGGTLVPSSMCSMTCTAGFRKIHQKETADCCFDCVQCPENEVSNDTADMEQCVRCPDDSYTNLEQTQCLQRTVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQDTCILQQTTFGVFFTVAISTVLAKTITVVTAFKLTTPGRMIRRRMIKVATNFLIPICTLIQLALCGIWLGTSPPFIDRDIQSEHGKVIIICNKGSIIAFYFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMIVVEVFSILASSAGLLGCIFVPKCYVLLVRPDLNVLQKKDELLYQ", "length": 854 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "RGD:1592277", "url": "https://alliancegenome.org/gene/RGD:1592277#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZXT3-1", "protein_name": "Vomeronasal 2 receptor, 69", "gene_name": "Vom2r69", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTVSFLFLKFSLILCSFTELSCFWRMKNSEDSDGDLRSDCGFVLLTTKKNIEDFYNDINEVRIPARRYEFFLVMFFATDEINNNPYLLPNISLIFSIIAGLCEDTLGVLDEIYSQQNNSWNIVNYICEKGQRCDIELTGPSWKASVKLSIHSMIPSVRMCDTGCVFFGPFNPNLSDHDQFPYMYQIATKDTCLSHGMVSLILHFRWNWLGLVISDDDQGIQFLSDLREEMQSHGICLAFVNMIPETMQVYMIKAKIYDKQIMTSSAKVVIIYGEMNSTLEVSFRRWSYLGVQRIWITTSQWDVITIKKDFNLDFFHGTLTFAHHKVEVAKFRNFMQTRNPAKYPVKFFESVLGWNYFNCSISKNSNLMDHFIFNNTLEWIALNKYDMVLSEEGYNLYNAVYAVAHTYHELILQQTESQNIAEPNGVFIDCQQVASLLKTRVFTNPVGELVNMKHREKQCVEYDIFITWNFPEGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTSVPSSMCSATCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDMYANLEQTQCLQRTVSFLAYDDPLGIALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTTPGRRLRGMMITWASNFVIPFCTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTIIICNKGSVIAFHVVLGYLGSLALGSFTIAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVVVEVFSILASSADLLGCIFVQKCYIILVSSNSNFLHK", "length": 849 }, "evidence": [ { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A8G4-1", "protein_name": "Vomeronasal 2 receptor, 60", "gene_name": "Vom2r60", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMLLLIFMFLLLQYSSDVYSFDRSSCAAKTKTSVYKDGDMVLAAFLPLFTITIDSASDNQSNNNFYIHQHVKECKFIHSFHFIVLAMVYAIEEINRNPHILPNVSLGYDIYNVLFNEWWILNRCITWLSGPKKYVPNYTCRREMKSIAALTGISWIISTNIGTLLELYKYPQLTIGSFDPNLNNHEQFHDIYQIAYKDMSLTHGIVSLLNYFHWNWVGLIVSEGQNGFQIISELRAEMDRNKICVDFVEMIRVSEVSYLPSYLLSPTHLAKSTANVIITYGDSDFMRGFLFYLRQILVTRKVWIMNSDWDVIIQSKHFILQSFHGSLIFAHHHKETSGYRNFIQTVHPSKYPEDFYLTRFWFYFFNCSFADDDCNTLENCLPNASLHETPGSHFDMVMTEFAYNIYNAVYAVAHSLHKMLLQQVEVTPVKEAEDLIFSAWQLHPFLKNMQFTNPAGEQVNLNEKMKLNADYDILNYWNFPEGLQLKVKVGQFSPYGPLGQQLSLSEDTIEWPTEITETPRSICSESCGPGFRKSLPEGKVSCCFDCVPCPENEISNETDVDQCMQCLDHQYANTAQNHCLQKSMTFLDYEDPMGISLSCIALCFSALTSLVLSIFLKQKNTPIVKANNRTLTYILLIALNFCFLCSFLFIGHPNTATCILQQTTFAVVFTVAVSTVLAKTITVVLAFKVTAPGRRIRWLLVTRAPNFIVPICTLIQIILCGVWLGNSPPFIDTDTRSEHEHIIIMCNKGSVTAFYCVQGYLGALALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVVVEVFSILVSSAGLLGCIFAPKCYIILLRPQRNSIQGHRDKIHYNYKTS", "length": 864 }, "evidence": [ { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PYF5-1", "protein_name": "Vomeronasal 2, receptor 17", "gene_name": "Vmn2r17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLCVFTISFLLMTFSLFLCSLTGPSCFWRIQNNEDNDGDLHRDCGFFLFTSEEPIKEDFYHFCIDFRIPARRYEVFLVMFFATDEINRNPYLLPNMSLIFCLIVGMCGDTLGYLEETHSPNNTWNSINYNCEIRPICDIELTGPSWTTSVKLAINSRKPKVFFGPFNSHLSDHDQFPYIYQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQSIQFLSDLREAMQRHGICLAFVNMIPENMQIYMTRGKIYDKQIMTSSAKVVIIYGEMNSTLEVSFRRWAYLCARRIWITTSQWDVITNKRDFSFDFFHGTVTFAHHNGEIVIFRNFLQTVNTSKYPLDISQTMQEWNYFNCSISKNSNSKMDHFTFNNTLEWTALQKLNMVLSEEGYNLYNAVYAVAHTYHELILQQVEFQKMAEPKGIFTDCQQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFNIWNFPQGLGLRVKIGSYYPCFPQNQQLHISEDLEWATGGTSVPTSMCSVTCTAGFRKIHQKQTADCCFDCAHCPENEVSNETADMEQCVRCPDDKYANLEQTHCLQRAVSFLAYEDPLGMALGCMALCFSALTLLVFFTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTAPGRRVRGMLVAGAPNLAIPICTLIQIVLCGIWLVTSPPFIGRDTKSEHGKTILICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLMFCSVWITFLPVYHSTRGKAMVVVEVFSILASSAALLGFIFVPKCYVILVKSDSNFREKYKNKFHY", "length": 849 }, "evidence": [ { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PZA6-1", "protein_name": "Vomeronasal 2, receptor 113", "gene_name": "Vmn2r113", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLILLFLLLNIPLIVADFIDPRCFWRIKQNKDEDGNLGSGCSFFIQAVQWPVEKEYFSSILNTQTHTENHKYALVLAFSINEVNRNSDLLPNMSLIFTFSALICDYESQLKSLIHLSLQNHEIFPNYICNDDVCAVALTGLNWTTTLTLYTILNNFISHQFLHLTYGPFHPVLSDHEEFPYLYQMASEDTSLALAMVSFIIHFSWNWVGLAISDNDKGIQFLSYLRREMEKNTVCFAFVSMIPVNMHLYMTRTEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLDIKRIWVTTSQWAITTGKKDFTFNNLYGTFAFGHHHGEISGFKNFVQTLNLLKYSDEYLVKLEWMYFNCEVSAPKCKTLKNCSSNHPLEWLMVRTFDMAFTEGSYAIYNAVYAVAHALHELTFQKFDNLPTDNVKEQNYACNKLGSFLRKIHFTNPVEDRVNMNQRNKLQENYDIFYVWNFPQGLGLKVKIGIFSPYIINGQQLHLSEDMLEWARGSTQMLTSVCSADCGPGFRKFGKNGMPACCFDCSPCPENEISNETNVELCVPCPEDQYANTEQNHCIHKALIFLTYKDPLGMALSLMALCFSAFTAVVLLVFVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCILQQVTFGVAFTVAVSTVLAKTITILLAFRVTAPQRMMKYFLVSGTYIYIIPICTLIQVIVCAVWLGAAPPSVDIDARSEHGHIIIVCNKGSVSAFYCVLGYLACLAFGSFTLAFLSRNLPSTFNEAKSITFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSTLASGAGMLICIFVPKCYIILFMPDRNSLQMIRKKSSSHAHLS", "length": 856 }, "evidence": [ { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PZX4-1", "protein_name": "Vomeronasal 2, receptor 87", "gene_name": "Vmn2r87", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMCVLTTSFLFLKFSLILCCLTEPICFWRIKDSEYNDGELQSECGFFLWTMEKPMEDDFYNVRFDFRIPASEYEFVLVMFFATDEINKNPDLLPNTSLVFSVIGGKCQDSLGLLGEEYILINDSLNYVNYVCKADDTCVIDLTGPSWKTSLKLAIDSWTPKVFFGPFNPNLSDHDRFPYVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGARRIWITTSQWDVITNKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSVLRWNYFNCSVSKNSIKMDHFTCKNPLEWTALHNYDMALSDEGYNLYNAVYAVAHAYHEHILHQVESQKMAEDKGKYTECQQLAPLLKTRVFTNPVGELVNMNQREYQCAEYDIFIIWNFPQGLGLKVKIGNYFPCFPRSQQLHISEDLEWVTGGTLVPSSMCSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEQSHCLQRTVSFLAYEDPLGMVLGSMALSSSAITILVLVTFMKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIEHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGKRMRGMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIDRDIQSEHGKTVIFCNKGSVIAFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKIMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSNFIQKYKGKLLY", "length": 848 }, "evidence": [ { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "RGD:1560816", "url": "https://alliancegenome.org/gene/RGD:1560816#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0E7-1", "protein_name": "Vomeronasal 2, receptor 115", "gene_name": "Vmn2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLLADFISPRCFWKMKQNENRDRNQGTGCTFMIHAVQRPVEKEYFSHILNIQTHTENHKYALALAFSIYEINMNPDILPNMSLIFEFSVHNCVWESKLMSFMHVSLQNYDIFPNYLCKEYTKCAMALTSLNWATTVKFNTILNNFISQQFFQITYGPFHPVLSDHEKFPYLHQMASDHTSLAFGLVSFIIHFGWNWVGLVISDNDQGIQFLSYLKTEMEKNTICFAFVNMIPMSMNLYMSKAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWNVSPGMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQITFQKFDNLPKDNGKEHNYSCKKLYSFLRKTQFINPVGDRVNMNQRDKLQEEYDIFYIWNFPHGLGFKVKIGIFSPYFPNGQQVHLSEDMIEWAKGSAQMPTSVCSADCGPGSRKFRMDGMAACCFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNHCIRKIVVFLSYEEPLGVALSLISLFFSAFTIVVLGVIVKHHSTPVVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGIVFTVSVSTVLAKTITVVLAFKIIASQRMMKYFLVSGAINYIIPVCILIQVIVCAVWLGASPPSVDIDGQSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVPKCYTILFRPDQNSLEMIRVKSSSNARSS", "length": 857 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C1-1", "protein_name": "Vomeronasal 2, receptor 118", "gene_name": "Vmn2r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMFTSIFIVLLLKLPLLLCNSAENMCFWRVKLNENCDGDLPQDCAFLLYTQVDPAPKDFLKYLFKSCLPSKIHQYLLSLYFAMEEINSNPYLLPNVSLGIEYFKGKCNGYLSLFTNLNIMTKYYHTFPNYICDPGACEIALTGPLWISSAQVATILQLKFIPQVRQITYGPFYPLLSDQSKFPNLHQIAPKNRFLPEAIVSLLFHFSWIWVGLVIQDDDQGIQFLLDIKEEMQRNGVCLAFVNVIPQNMHLFTTRAEKYYNQIITSSANVVILYGELNTALEVSFKHWKYLGTQKIWFTTSQWDAITREKDFSLTSFYGTLTISQYHGDVSTLNNFFQGANLSKDTHYFSSERLGWMYFNCSILKSNCKTPNQCTSSNLLEWLPRHSFDMAMNDESYNIYNAIYAVAHALHEMVLQKIDFQQLENVTQLMQECVQIHAFLENMQFLNPIGDVVIINQQAKTDAEYEIYMIWNFPQGLGVKVKIGRFYSYFLHDQKLYLYEDMIQWASGYSQIPPSVCSVSCAPGFKKFYLEEKPSCCFDCSPCPENEISNATDLTQCVKCPDGQYANIERNHCFPKVVTYLAYADPLGIVLACMALFLSMLSVLVLGIFVKNQYTPIVKANNRTLSYILLISLTLCFLCSLFFIGHPSTARCLLQQITFGILFTVAVSAVLAKTITVLLAFSITIPGRRVKWLLLFGTHKVIIPICSLFQLIICGFWLGLSPPFVERDTHTEHGHIIIMCNKGSLIAFYSVLGYLGCLALASFIMAFLVRNLPDTFNEAKFLTFSMLVFCSVWVTFLPVHHSTKGKAMVAVEVFSILASSAGLLGCIFIPKCYIIVLRPDRNFIQRSKGKNHS", "length": 853 }, "evidence": [ { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q281-1", "protein_name": "Vomeronasal 2, receptor 114", "gene_name": "Vmn2r114", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLLADFISPRCFWKMKQNENRDRNQGTGCTFMIHAVQRPVEKEYFSHILNIQTHAENYKNVLALAFSIYEINRNPDILPNMSVRFTISKYNCYWESELMSLIHLSLQNHDILPNYMCKELTRCTMALTRLNWVTTVKLNTILNNFISQQFFQITYGPFHPVLSDHEKFPYLYQMASDHTSLALALVSFIIHFSWNWVGLAISDNDQGIQFLSYLRRVMEKNAVCFAFVNMIPMSMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQIAFQKFDLPKDNGKEHNYSCKKLYSFLRKTQFTNPVGDRVNMNQRDKLQEEYDIFYIWNFPQGLELRVKIGMFSPYFPNGQQVHLSEDMIEWAKGSAQMPTSVCSAECGPGSRKFRMDGMAACSFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNHCIRKTVVFLSYEEPLGVALSLISLFFSAVTIVVLGVIVKHHSTPVVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGVVFTVSVSTVLAKTITVVLAFKITASQRMMKYFLVSGAINYIIPFCILIQVIVCAVWLGASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGRVMVAVEIFSILASSAGMLGCIFVPKCYTILFRPDQNSLEMIRAKSSSRAHIS", "length": 856 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4X4-1", "protein_name": "Vomeronasal 2, receptor 11", "gene_name": "Vmn2r11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLRTFTISFWLLKFSLILCHVTEPICFWRIKNNKDNDGDLRSDCNYFLWTFEETTEINFYNIVDFRIPTRRYEFFLVLFFATDEINKNPDLLPNISLIFWLFGGQCEDEWGVLDTNYSQNNINVKFINYDCLSPNCYIDLTGPSWKTSLKLPNILTIIVLMWMSHPLFYILQVFFGSFNPNLSDHDQFPYVHQVATKDTLLSHAMVSLMLHFRWTWIGMVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPENMQIYMTRAKIYDKQIMESTAKVAIIYGEMNSSLEVSFRRWEDLGVRRIWITTSQWDVITNKNDFSLDFFHGTVTFEHHHSEIAKFKNFMQTINTDKYPVNISESILGWNYFNCSTSMNSYSKMDHLTFNNTSEWTALHKYDMALSEEGYNLYNAVYAVAHTYHELILLQVESQQMAVPKGTFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFSQGLGLKVKIGSYLHCYPRSQQLHISEDLEWVTGGSSVPSSMCSMTCTAGFRKIHQNETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGIALGCMALFLSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNLVIPICTLIQLVFCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILVRLDSNFLQKYEHKLPS", "length": 861 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "RGD:1592277", "url": "https://alliancegenome.org/gene/RGD:1592277#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6I0-1", "protein_name": "Vomeronasal type-2 receptor 116", "gene_name": "Vmn2r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFLFLNIPLLVADFISPRCFWKMKQNEYRDRHHGTGCIFLILAIQQPVKKEYFSHILNIQTHTENHKYALALAFSIYEINRNPDLLPNMSLIFIFSADSCEWESELSLIRFGLQNSDNLPNYLCEELTKCILALTNMNWATTVTLHTILSNFLSDQLLHITYGTFHPALSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTLCFAFVNMIPLNINLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNKYGTFAFEQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLKWLMVHTFDMAFIEESYYIYNAVYAFAHVLHQFTFQKFDNLPKDNGKEHNYSCKKLYSYLRKNHFINPVGDRVSMNQRDKLQEEYDIVYIWNFPQGLGLRVKIGMFSPYFPNGQQVHLSEDMLKWARGSTQVPTSMCSADCGPGSRKFRMDGMAACCFHCKPCPENEISNETNVDNCVQCPEDQYANTEQNHCIRKAVVFLSYEEPLGVALSLLSLCFSAFTTVVLGIFVKHHNTPIVKANNRTLTYLLLISLIFCFLCPLLFIGHPNSATCILQQLTFGVVFTVSLSTVLAKTITVVLAFKIIASQRMMKYFLISGAINYIIPICILIQVIVCAVWLRASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLAILAFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVPKCYTILFRQDQNSLEMIRVKSSSNVHVS", "length": 856 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q759-1", "protein_name": "Vomeronasal 2, receptor 14", "gene_name": "Vmn2r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNLRGFGLSFMLLKFSLIWCHLTEPICFWRIKNNEDNDGDLRSDCGFFLAAVEGPIDHTYNISDFRIPARRHEFFLVLFFATDEINKNPYLLPNMSLIFPEDPGQCEKLLGELDKIHSEAKFTVDFTDYICAGYGTCYIGLIGPSWKTSVKLSTNSGTPRVFFGPFNPKLSDHDQFPYVHQVATKDTHLSHGMITLMLHFRWTWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPEDMQLYMTRAKIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGARRIWITTSQWDVITNKNDFSLDFFHGTVTFEYHHSEIAKFKNFMKTMNTDKYPVNISESILRWNYFNCSTSMNSYSKMGHFTFNNTLEWTALHNFDMALSEEGYNLYNAVYAVAHTYHELILLQVESQQTEEPKGTFTDCQQVSSTLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGSYLPCFPQSQQLHISEDLDWATGGSSVPSSLCSVTCTAGFRKIHQKQTADCCFDCDQCPENAVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCMALTFSALTVLVLVTFVKYKDTPIVKANNRILSNILLISLVFCFLCPLLFIGHPNKATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTSPGGKMRGMLASGAPNLVIPICTLVQLVLCGIWLVTSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFVPKCFVILVRPDSNFLQKYKDKLFY", "length": 848 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "RGD:1592277", "url": "https://alliancegenome.org/gene/RGD:1592277#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LNQ1-1", "protein_name": "Vomeronasal 2 receptor, 68", "gene_name": "Vom2r68", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKELCTFTISFLLLKFSFIMWGLTEPSCFWRIKNNGDNDGDLRTDCGFVLFTRQEPIEENFYNEIVYFRIPARSYEFFLVMFFATDEINKNPYLLPNMSLIFSLIVGMCEDTLEYVDTNYSFKRNTLNIVNYNCYLRARCYIQLTGPSWKTSLKLTINSRKPKVFFGPFNPNLSDRDQFPYVNQIARKDTFLSHAMISLMLFFEWTWIGLAISDDDQGIQFLSVTREVMQKHSICSAFVNVIPENMQIYMARANIYDKQIMTSSAKVVIIYGERNSTLEVSFRRWEYLGAQKIWITTSQWDVITNKRVFSLDFFHGTVTFAYHNGRIPKFRNFMQTMNTSKYPVDISQTILEWNYFNCSIFKNSDSEMNHFTSKNTEEWLAQHKFDMVLSEEGYNLYNAVYAVAHTYHELILQEVESQKILRHKGRFINCQQVASLLKTRIFMNPVGELVNMNQRENQCAEYDIFNIWNFPQGLGLKVKIGSYFSCFPQSQQLQISEDLKWATGGTSVPTSMCSVTCTAGFRKIHQNEAAHCCFDCALCPENEVSNDTDMEQCVRCPDDKYANLEQTYCIQRHVSFLAYEEPLGLTLGCMALCFSALTILVLVTFVKHKNIPVVKANNCILSYILLISLIFCFLCSLLFIGHPKKTTCILQQITFGIFFTMAISTVLAKTITVVMAFKLTTPGRRMRRILASGAPNLIIPICTLIQLVICGTWLATSPPFIDRDIQSEHGKVIIICNKGSVTAFHFVLGYLRSLALGSFAVAFLARNLPDRFNETKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCVFIPKCYVILVRPNSNFLQKYKNKLLY", "length": 849 }, "evidence": [ { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "RGD:1560816", "url": "https://alliancegenome.org/gene/RGD:1560816#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3UW56-1", "protein_name": "Vomeronasal 2, receptor 85", "gene_name": "Vmn2r85", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMCSLTMSFLFLKFSLILCCLTEPICFWRIKSSEYNDENLQSECGYFLWTMKKLMKDDFYNVRLDFRMPAREYEFVLVMFFATDEINKNPDLLPNTSLVFSVMADKCQDSLGILDLKYMLVNDTLNYVNYVCEADDSCAIGLTGPSWKASLKLAIDTWAPKVFFGPFNPNLSDHDRFPNVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGVQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGAQRIWITTSQWDVITNKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPISISESILRWNYLNCSVSKNSIKMDHFTCKNPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILQQVESQKMVEDKGKYTECQQLAPLLKTRVFTNPVGELVDMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTSVPSSMCSVTCTAGFRKIHQKETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANIEQTHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGRRMRGMMMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIERDIQSEHGKTVIFCNTGSVLSFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSHFIQKYKGKLHY", "length": 850 }, "evidence": [ { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "RGD:1560816", "url": "https://alliancegenome.org/gene/RGD:1560816#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8Y4-1", "protein_name": "Vomeronasal 2, receptor 86", "gene_name": "Vmn2r86", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMCALTISFLLLKFSLLLCCLKEPICFWRIKSSEYNDGDLQSECGYFLWTMKKLMKDDFYNVRLDFRIPASEYEFVLVMFFATDEINKNPDLLPNTSLVFSVMAGKCQDSLGNLDIQYMLINDSLNYVNYVCDIDDSCAIGLTGPSWKTSLKLAIDSWTPTVFFGPFNPNLSDHDRFPNVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGARRIWITTSQWDVITNKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSILRWNYFNCSVSKNSIKMDHFTCKNPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILHQVESQKMVEDKGKYTECQQLALLLKTRVFTNPVGEMVNMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPWSQQLHISEDLEWATGGTSVPSSICSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETVDMEQCVRCPDDKYANLEQMHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGKRMRGMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIERDIQSEHGKTVIFCNKGSVLSFHVVLGYLGSLALGSFIVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSNYIQKFKGKLLY", "length": 848 }, "evidence": [ { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "RGD:1560816", "url": "https://alliancegenome.org/gene/RGD:1560816#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N5U4-1", "protein_name": "Predicted gene 14496", "gene_name": "Gm14496", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKQLCAFTISFLLLKFSLILCCLTEPICFWRIKNSEDDDRDLQRECHFYLWAIDKPIEDDFYNIVYNFRIAASEYEILLIMFFATDEINKNPYLLPNITLIFTIIGGHCHDLLGGLDEAYTQINGRVKFVNYFCYSDDSCLIGLTGPSWKTSLKLAMDSSMPMVFFGPFNPNLCDHDRLPHVHQVAPKDSHLSHGMVSLMFHFTWTWIGLVISDDNQGIQFLSDLRKEMQRHGICLAFVNMIPENMQIYMTRATIYDKQIMTSSAKVVIIYGDMNSTLEISFRRWEDLGAQRIWITTSQWDVITNKKDFTLNLFHGTVTFAHYKGEIPKFRNFMQTINTDKYPVDISHTILEWNYFNCSSSKNSSKMDHFTFNNTLEWTALHKYDMALSEEGYNLYNAVYAAAHTYHEHFLQQAESQKRADPKRDFTECQQVSSLLKTRVFTNPVGELVNMMHGENECTEYDIFIIWNFPQGLGLKVKIGSYLPCFPQSQQLHISDDLEWAMGGTSVPSSMCSMTCTAGFRKIHQKETADCCFNCVPCPENEVSNETADMEQCVMCPDDKYANIEQTHCLQRTVSFLAYEDPLGMALGCMALSFSAITTLVLVTFVKYKDTPIVKANNRILSYILLISLDFCFLCSLLFIGHPTQVTCILQQTTFGVFFTVAVSTVLAKTITVVMAFKLTTPGRRMRGMMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIKSEHGKTVILCNKGSVIAFHFVLGYLGFLALGSFTVAFLARNLPDRFNEAKFLTFSMLMFCSVWITFLPVYHSTRGKVMVAVEVFSILASCAGLVGCIFFPKCYVILIRSDSIFIQKYKDELHY", "length": 849 }, "evidence": [ { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "RGD:1560816", "url": "https://alliancegenome.org/gene/RGD:1560816#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N621-1", "protein_name": "Vomeronasal 2, receptor 10", "gene_name": "Vmn2r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNLCVFTLSFFLLEFSLILCHLTEPICFWRINNNEDNDGDLRSDCGFFLAAVEGPTDDSYNISDLRIPARRYEFFLVMFFATDEINKNPYLLPNMSLIFPINHGQCEKTLGDLDKIYSEKNYTVEFTDYICVSFGTCFIALIGPSWKTSIKLSINSGTPRVFFGPFNPKLSDHDQFPYVHQVATKDTRLSHAMVSLMFHFTWIWIGMVISDDDQSIQFLSDMREEMQRHGICLAFVNMIPEDMQLYMTRATIYDKQIMESTAKVVMIYGEMNSTLEVSFRRWEDLSIRRIWITTSQWDVITNKNDFSLDFFQGTVTFAHHVGEIANFRNFLQTMNSEKYTVNISESRLGWNYFNCSISKNSNKKDHFTFNNTLEWTTLHKYDMVLSEEGYNLYNAVYAVAHTYHELVLQQVESQQMTVPKGTFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYLPCFQQSQQLHISEDLEWATGGSSVPPSLCSVTCTAGFRKIHQKQTADCCFDCDQCPENAVSNETVDMEQCMRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCTALSFSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNIVIPICTLIQLVLCGIWLVTSPPFIDRDMQSEHGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTQGTVMVVVEVFSILASSAGLLGCIFLPKCCVLLRIQNSNFLHKYKHELHS", "length": 847 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "RGD:1592277", "url": "https://alliancegenome.org/gene/RGD:1592277#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N674-1", "protein_name": "Vomeronasal 2, receptor 111", "gene_name": "Vmn2r111", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFLLLNIPLLVADFIHPRCFWKMKRNENKDRNQGTGCTFVIHAVQQPVEKEYFSHILNIQTQTENRKYALALAFSINEINRNPDLLPNMSLIFKFSAHNCVWESEIMNLMLLSLQNYDIFPNYLCKEYTKCAMALTNLNWATTVTLYTILNNIISEQFLQITYGPFHPVLSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTVCFAFVNMIPVNMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPRMKDFTFGNKYGTFDFQQHNSEISGFKNFVQTLNSVKYPDDYLVELEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEKSYYIYNAVYAFAHALHQFTFQKFDNLPKDNGKEHNYSCKKVDPSLRKMQFTNPVGDIVNMNQRDKLQEEYDIFYIWNFPQGLGLRVKIGMFSPYLPNGQQVHLSEVIIKWTKGSTQVPTSVCSADCGPGSRKFGMDGMAACCFHCKPCPENEISNETNVDNCAQCPEDQYANTEQNHCIHKAVVFLNYEEPLGMALSLFSLCFSAFTTVILGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCILQQITFGVVFTVALSTVLAKTIVVVLAFKITASQRMMKYFLVSGASNYIILICTLIQVIVCAVWLGASPPSVDIDAQSEHGHIIIVCHKGSVNAFYSILGYLALLSFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVSKCYTILFRPDRNSVEMTRVKSSFHARVS", "length": 857 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T2-1", "protein_name": "Vomeronasal 2, receptor 67", "gene_name": "Vmn2r67", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKISFMFCHLSDPKCFWRIKDTKKNLGDTETYCSFSISTKRGYVKNDYFSWNLDKQVTPKTNHLIFSVYLALEEINMNFHILPNISLVVNIECLRKKYDEKTGLALQTEEFIPNYYCTDERRYLIIFTAPIWAVTTRLGTFMFMYSIPELYCGHFHLSLSDNEQFPHLYQISPKDTSLPLAMVSLMVHFRWNWIGAIVTTDDHGIQFLSELRGEMQKHIVCLSFEITILTEHSMARKEFQRYFNRIVMSSAKVVIVYGDYTSPIDLVLHLCKSKGIFRIWVSVSQFDMITKLGDFMLYSSSGTFIFSHQKPELSGFQQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKIVFKWLFMTPLGMAMSDTCYNLYNAIYAVAHSLHEMLLQQIDTWSNNAGKELEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTDYDIFYIMDFQKDYGFKMKIGRFSGHLPSHQQLYMSKEMMEWATDVDQILPSICSMPCRPGLRKSPEEGKDICCFVCNPCHENEISNMTNMDQCVKCQEDQYANEDHTLCLQKVVSILDYRDPLGKALAGIALCFSVLTSGILCIFLKHRETPIVKANNQTLSYVLLISLVFCFICSLLYIGHPTTVICILQPITFAIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLLSGVPKYIVLICTMIQLILCGIWLGTSPPFVDADVYMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFSILASSAGLLLCIFAPKCYIILLRPQTNSFHKFRKTHSKAENIS", "length": 851 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6V1-1", "protein_name": "Vomeronasal 2, receptor 117", "gene_name": "Vmn2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLVSDFIYPRCFWKIKQNEDKNRNQGTECTFMIHAVQRPVEKEYFSHILNIQTHTENHKYALALAFSIYEINRNPDILPNMSLTFKFSNYNCHWKSKYNSFIHLSLQNHDILPNYMCKEFTKCAMALTRLNWATTVKLNTILNNFMSQQFLQITYGPFHPVLSDHEKFPYLYQMASDHTSLALALVSFIIHFSWNWVGLVISDNDEDIQFLSYLRREMEKNTVCFAFVNMIPMSMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQIAFQKLDNLPKDNGKEHNYSCKKLYSFLRKTQFTNPVGDRVNMNRRNKLQEEYDIFYIWNFPQGLGLRVKIGMFSPYFPNGQQVHLSEDMIEWAKGSAQVPTSVCSAECGPGSRKFRMDGMAACCFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNQCIRKTVVFLSYEEPLGMALSLLSLCFSAFTTVVLGVMVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGVVFTVSVSTVLAKTITVVLAFKITASQRMMKYFLVSGAINYIIPICILIQVIVCAVWLRASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYYSTKGKVMVAVEIFSILASSAGMLGCIFVPKCYTILFRPDQNSLEMIRVKSSSNAHVS", "length": 857 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z8-1", "protein_name": "Vomeronasal 2, receptor 9", "gene_name": "Vmn2r9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLRTFTISFWLLKFSLIFCHVTEPICFWRIKNNEENDGDLRSDCNFFLWTYDESTEINFYNIVDFRIPARRYEFFLVLFFATDEINKNPDLLPNMSLIVWLLGGQCGDEWSVLYKNYSQENINVEFINYDCLSPDCYIHLTGPSWKTSLKMSIQSRTPKLFFGPFNPNLSDHDQFPYVHQVATKDTHLSHAMVSLMLHFRWAWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPKDMQIYMTRATIHDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGARRIWITTSQWDVITNKNDFSLDFFHGTVTFEHHHSEIAKFKNFMKTMNTDKYPVNISQSIGGWNYFNCSTSMNSYSKMDHLTFNNTSEWTALHNFDIVLSEEGYNLYNAVYAVAHTYHELILLQVESQQTEVRKGIFNDCQQVSSMLKSRIFTNPVGELVNMKHRENQCAEYDIFIIWNFPQGLGLKVKIGSYLPCFQQSQQLHISEDLDWATEGTSVPSSMCSVTCTAGFRKIHQNETADCCFDCDRCPENEVSNETADMEQCVSCTGDKYANLEKTHCLQRAVSFLAYEDPLGMSLGCIALFLSALTSLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNLVIPICTLIQLVFCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCAILVRLDSNFLQKYKDKLPS", "length": 848 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "RGD:1592277", "url": "https://alliancegenome.org/gene/RGD:1592277#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X2-1", "protein_name": "Vomeronasal 2, receptor 13", "gene_name": "Vmn2r13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKELCVFILCFLLLKFSLILCHLTEPICFWRIKSNEDNDGDLRSDCGFFLAAVEGPIDQIYNISDFRIPARRYEFFLVLFFATDEINKNPYLLPNMSLISPITSGQCEKTLGDLDKIYSEKNITVEFTDNICVFYGACYISFIGPSWKTSVKLSIHTGTPRVFFGPFNPKLSDHDQFPYVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQFLSDMREEMQRDGICLAFVNMIPGNMQLYMTRAKIYDKQIMESTAKVVIIYGEMNSTLEVGFRRWIHLGVRKIWITTSQWDVVTNKKDFSFNFFHGTVTFAHHIGELVKFRNFLQTMNNEKYPVNISETRLGWNSFNCSISKNSNKKDHFTFNNTLEWTARNNFDMVLSEEGYNLYNAVYAVAHTYHELILQQVESQQMAVPKGIFTDCQQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFIIWNFPKGLGLKVKIGSYLPCFHQSQQLHISEDLEWATGGTSVPSSMCSVTCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANVEKTHCLQRVVSFLAYEDPLGMALGCMALSFSALTVLILVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQITFGVFFTVAISTVLAKTITVVLAFKLTTPGRRMRGMLASGAPNLAIPICTLIQLVLSGIWLVKSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILD", "length": 831 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "RGD:1592277", "url": "https://alliancegenome.org/gene/RGD:1592277#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N217-1", "protein_name": "Vomeronasal 2, receptor 12", "gene_name": "Vmn2r12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLCVFILFFMLLKFSLISHHLTEPICFWRIKNNEDNDGDLRSDCGFFLAAVEGPIDQIYNISNFRIPARRYEFFLVLFFATDEINKNPYLLPNMSLISPIASGQCEKTLENLDKIYSEKNHTVQFTDNICVFYETCYISLIGPSWKTSVKLSIHHGTPRVFFGPFNPKLSNHDLFPNVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQCIQFLSDLREEMQGHGICLAFVNMIPEDMQLYMTRAEIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDKGVRRIWIATLQWDVITNKKDFTLDFFQGTVTFAHHVGDIANFRNFLQTMNNEKYPINISESILQWNSFNCSFSKNSNKKDHFTFNNTLEWTALHIYNMVLSEEGYNLYNAVYAVAHTYHELILQQVESQQTEVPKGTFTDCQQVSSMLKSRIFTNPFGELVNMKHQESQCADYDIFIIWNFPKGLGLKVKIGYYLPCYQRSQQLHIYDLEWATGGTLVPSSMCSVACTAGFRKIHRKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCMALFLSALMVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCPLLFIGHPNLATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNLVIPICTLIQLVLCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVYCSVWITFLPVYHSTRGAVMVVVEVFSILASSAGLLGCIFLPKCCVILLD", "length": 831 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "RGD:1592277", "url": "https://alliancegenome.org/gene/RGD:1592277#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N221-1", "protein_name": "Vomeronasal 2, receptor 112", "gene_name": "Vmn2r112", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFLLLNIPLHVADFIHPRCFWKMKRNENKDRNQGTECTFVIQAVQQPVEKEYFSHILNIQTQTENRKYALALAFSINEINRNPDLLPNMSLIFKFSAENCVWENKLMSLMHSSLQNYDILPNYLCEEYTECVMALTSLNWATTVTLYTILNNFMSEQFLQITYGPFHPVLSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTVCFAFVNMIPVNMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNKYGTFDFQQHNSEISGFKNFVQTLNSVKCPDEYLVELEWMHFNCEVSASKCKPLKNCSSSYSFDWLMEHTFDMAFIEKSYYIYNAVYAFAHALHQFTFQKFDNLPKDNGKKHNYSCKKVDSSLRKTQFTNPVGDIVNMNQKGELQEEYDIFYIWNFPQGLGLRIKIGMFSPYFPNGQQVHLSEVMIRWAKGSTQVPTSVCSADCGPGSRKFEMDGMAACCFHCKPCPENEISNETNVDNCVQCPEDQYANTEQNHCIHKAVVFLSYEEPLGMALSLLSLFFSAFTTVILGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCFLQQITFGVVFTVALSTVLAKTITVVLAFKITASQRMMKYFLVSGASNYIILICTLIQVIVCAVWLGASPPFVDIDAQSEHGHIIIVCHKGSVNAFYSILGYLALLSFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGILGCIFVSKCYTILFRPDRNSVEMTRVKSSFHAHIS", "length": 857 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A0-1", "protein_name": "Vomeronasal 2, receptor 15", "gene_name": "Vmn2r15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLRVFTFSLLLLKCFLISCHLTEPICFWRLKNNEDNDGDLRSDCGVFLAAVEGPIDQIYNISDFRIPARRYEFFLVMFFATDEINKNPYLLPNMSLISPVDHGQCEETLGLLDEIYLEKNNSVEFTDYICVFYGTCYIGLIGPSWKTSVKLSIHSRTPRVRMCETRLVFFGPFNPNLSDHDQFPYVHQVAIKDTHLSHGMASLMLHFRWTWIGLVISDDDQSIQFLSDLREEMQRHGICLAFVNMIPEDMQLYMTRAKIYDEEIMTSTAKVVIIYGEMNSTLQVSFRRWEDLGVRRIWITTSQWDVITNKNDFSLDFFHGTVTFAHHVGKIAKFRNFLQTMNSDKYPVNISKSILGWNYFNCSVSKKGNKKDHFTFNNTLEWTALHNFDIVLSEEGYNLYNAVYAVAHTYHELILQQVESQQTAVPKGIFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGNYLPCYPWSQQLHISENLEWATGGSSVPSSMCSVTCTAGFRKIHQKQTADCCFDCDQCPENEVSNETADMEQCVRCPDDKYANLEKTQCLQRVVSFLAYEDPLGMTLGCMALTFSALTVLVLVIFVKYKDTPIVKANNRIVSYILLISLVFCFLCSLLFIGHPTQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGGRMRGMLASGAPNLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILLRPDLTFLQKYKDKLPS", "length": 855 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "RGD:1592277", "url": "https://alliancegenome.org/gene/RGD:1592277#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N472-1", "protein_name": "Vomeronasal 2, receptor 8", "gene_name": "Vmn2r8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLRTFTISFLLLKFSLILCHVTDPICFWRIKNNEENDGDLRSDCNFLLWTDYESTEFNFYNIVDFRIPARRYEYFLVLFFATDEINKNPDLLPNMSLIVWLLSGQCGDEWSVLHKNYSQENINVKFINYDCLSPACYIDLTGPSWKTSLKMSIQSRTPKVFFGPFNPDLRDHDQFPFVHQVATKDTYLSHAMVSLMHHFRWMWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPENMQIYMTRATIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGVRRIWITTSQWDVITNKNDFSLDFFHGTVTFEHHHSEIAKFKNFMKTMNTDKYPVNISQSIVGWNYFNCSTSMNSFSKMDHLTFNNTLEWTALHNFDMVLSEEGYNLYNAVYAVAHTYHELILLQVESQQTEVPKGIFTDCQQVASMLKSRIFTNPIGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGSYLHCFSQSQQLHISEDLEWATGGTSVPSSLCSVTCTAGFRKIHQNETADCCFDCDQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPWGMALGCMALFLSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNLVIPICTLIQLFLCGIWLVTSPPFIDRETQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILVRLDSNFLQKYKDKLPS", "length": 848 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "RGD:1592277", "url": "https://alliancegenome.org/gene/RGD:1592277#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R9L8-1", "protein_name": "Vomeronasal 2 receptor, 77", "gene_name": "Vom2r77", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMFTSIFIVFLLKLPLLLSNSTENMCFWRANFNENCDGDLLHDCAFLIYTDEEPAPKDFFKYLFKLCLPSKIYQYVLSLYFAIMEINGNPYILPNVSLEIAYFRGECNGYLSLLTNLNIMTKYQHTLPNYVCNPGACEIVLTGPLWKSSAQVATILQLNFIPQITYGPFHPLLSDQIKFPNLHQIAPKDRFLCEAIVSLLFHFSWTWVGLVVEDNDQGIQFLLDIKGEMQRNGVCLAFVNVIPQNMQLFTTRAEIYYNKIITSSANVVIIYGEMNTALEVSFKHWKYLGTQKVWFTPSQWDVITREREFTSTSFHGTFTISQYHGDVSILNNFIYRMNLSKDTHYFSPERLGWMYSNCSLLKSNCKTPNQCTSSNSWEWLPWHSFDMAMNDECYNVYNAIYAVAHALHEMILQKIDFQQRNNVSQLMQECLKVHEFLQKMKFFNPVGDIVVINQRTKRDAEYEIHMVWNFPQGLGMKVKIGRFFSHFLHDQKLYLYEDMIQWALGYSQIPTSICSMSCAPGFKKSYPEEKASCCFACSPCPENEISNATDLAQCVKCPDGQYANIERNHCFPKAVTFLDYADPVGIVLVCMALCLSTLSALILGIFVKKQNTPIVKANNRTLSYILLVSLTLCFLCSLLFIGHPSTARCVLQQITFGTLFTVAVSTILAKTITVLLAFSITVPGRRVTWPLFVASKVIIPICSLFQLMLCGLWLGLSPPFVERDAHSEYGHIIIMCNKGSIIAFYCVLGYLGCLALASFIVAFLGRNLPDTFNEAKFLTFSMLVFCSVWVTFLPVFHSTKGKVMVAVEVFSILTSGAGLLGCIFIPKCYIIVLRQDRNFIKKVKGKNHS", "length": 849 }, "evidence": [ { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1LV89-1", "protein_name": "Olfactory receptor CQ3 precursor", "gene_name": "olfcq3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLNICLHLSFIFISVNSDSCQIQGHFKLNRMYKDGDYIIGGLFEVQHLKVFPELSFRMEPEQPKCEEFYMSSFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCLKLVVAFRAATTLISGTEETFSNFNCTGPPPVIAIVGDPGSTHSIAVSSVLGLFHVPLISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMVQILKYFGWTWVGVLYSDDDYGIYAAQSFQQEMQRFKGCVAFSEIVPYDNHRDIQRIVAVIKASTARVVVAFSTDLLPLMEELLQQNVTGRQWIASEAWSTSPVLHLPRFVPLVRGTLGIAIHRGKIKGLHEFLLHIQPDNDPTNNMVRIFWENMFGCSFEKGNGYGEKMCTAQEDLNITVNEYNDVSELRASYNVYKAVYALAHALHDLMQCEEGRGPFSGNSCADITKLKPWQMVPYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWHPSSDGLIVVRTVGVVDEGASAGRVLTLDEDAIYWNFETKKPPRSVCSESCPPGTRRAMRKGLPVCCFDCLPCADGEISNMSDATECTSCPNEFWSSPKKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVLAVFAHHHNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAMFGISFVLCVSSILVKTMVVIAVFKSSRPEGKSAVKWFGAVQQRGTVLVLTAVQIVICVVWLSTASPTPHKNILYVRSKIVFECSIGSMAGFAILLGYIGILAAVSFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFIPAYVSSPGKYSVAVEIFAILASSFGLLVAIFVPKCYIIILHPERNTKKAIMGRTAEK", "length": 855 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFV7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFV7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PFV7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFV7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 604, "end_pos": 606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PFV7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PFV7" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 570, "end_pos": 834, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 20, "end_pos": 22 }, { "start_pos": 288, "end_pos": 290 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 427, "end_pos": 429 }, { "start_pos": 533, "end_pos": 535 }, { "start_pos": 604, "end_pos": 606 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PG87-1", "uniprot_ac": "A0A8M9PG87", "uniprot_id": "A0A8M9PG87_DANRE", "mass": { "chemical_mass": 64664.0, "monoisotopic_mass": 64664.0 }, "refseq": { "ac": "XP_073797477", "name": "uncharacterized protein C18orf63 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073797477" }, "gene_names": [ { "name": "si:ch211-152c8.2", "type": "recommended", "evidence": [ { "id": "A0A8M9PG87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG87" } ] }, { "name": "si:ch211-152c8.2", "type": "synonym", "evidence": [ { "id": "XP_073797477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073797477" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C18orf63 homolog", "type": "synonym", "evidence": [ { "id": "A0A8M9PG87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG87/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C18orf63 homolog", "type": "synonym", "evidence": [ { "id": "XP_073797477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073797477" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073797477", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073797477" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG87", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG87" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-152c8.2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG87", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-383", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-383", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PG87", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PG87", "database": "AlphaFoldDB", "categories": [] }, { "id": "100006059", "url": "https://www.ncbi.nlm.nih.gov/gene/100006059", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031643", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031643", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100006059", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006059", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PG87", "url": "https://www.orthodb.org/?gene=A0A8M9PG87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28495", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28495", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28495:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28495:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15813", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15813", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073797477", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073797477", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PG87", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PG87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-383", "url": "https://zfin.org/ZDB-GENE-091204-383", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSGSGAQSLFSLDLPDLRNLCCVNLFFPNSHDEGELRNKQVKTCRELILMQSDIVASPVLGHYGGISVIMTTALHKTGFIQAFAEKHGLQLCPPQRVFPAILQNCLSYTVTTKLAPKWNKAGQYLIAGKDFLSDTGKLNAVVLEMNITETQLCGNVEVKTVRLPPAEIQDFDFPAPVVINFLHTKEAVLHTVMPNSWCHILPSMKKGQIISISRRIPEESPFQSYLDIQKHWSNMYGYQLPSVGEEDVIYCSVYFKPIGDKLFTYPLSCIRTQPIQCFPRVDLQGVLRTFISDLQAELKSVCGFPVQMTCKTCFYNSELNRPVAQYSAGLPVNLTTENSSRGVLNPLPSSNPRDTTKHHYSQCDSTGKPTEKRKRLNLDSSLHQKDWTSSNLATQFSSSPTNIHFTQIQAQYVPPRPKLVPVFNCKPVNATEVYSANRLTAVVRPLSSISISSSSEPHCSTSPARVNQITRPSVPQRMTLPFSKSKADTRILPPLPFSQTIPQIVPQIPSNTGGDMIQSKPKRLKQSLQDVEVHARNNQLSKINISTLHAWLKSRGINVRSKDKKEELVSRVMRSLSES", "length": 579, "header": "tr|A0A8M9PG87-1|A0A8M9PG87_DANRE Isoform 1 of Uncharacterized protein C18orf63 homolog OS=Danio rerio OX=7955 GN=si:ch211-152c8.2 PE=4 SV=3 CANONICAL=A0A8M9PG87-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PG87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG87/entry#A0A8M9PG87-1", "sequence": { "sequence": "MSGSGAQSLFSLDLPDLRNLCCVNLFFPNSHDEGELRNKQVKTCRELILMQSDIVASPVLGHYGGISVIMTTALHKTGFIQAFAEKHGLQLCPPQRVFPAILQNCLSYTVTTKLAPKWNKAGQYLIAGKDFLSDTGKLNAVVLEMNITETQLCGNVEVKTVRLPPAEIQDFDFPAPVVINFLHTKEAVLHTVMPNSWCHILPSMKKGQIISISRRIPEESPFQSYLDIQKHWSNMYGYQLPSVGEEDVIYCSVYFKPIGDKLFTYPLSCIRTQPIQCFPRVDLQGVLRTFISDLQAELKSVCGFPVQMTCKTCFYNSELNRPVAQYSAGLPVNLTTENSSRGVLNPLPSSNPRDTTKHHYSQCDSTGKPTEKRKRLNLDSSLHQKDWTSSNLATQFSSSPTNIHFTQIQAQYVPPRPKLVPVFNCKPVNATEVYSANRLTAVVRPLSSISISSSSEPHCSTSPARVNQITRPSVPQRMTLPFSKSKADTRILPPLPFSQTIPQIVPQIPSNTGGDMIQSKPKRLKQSLQDVEVHARNNQLSKINISTLHAWLKSRGINVRSKDKKEELVSRVMRSLSES", "length": 579, "header": "tr|A0A8M9PG87-1|A0A8M9PG87_DANRE Isoform 1 of Uncharacterized protein C18orf63 homolog OS=Danio rerio OX=7955 GN=si:ch211-152c8.2 PE=4 SV=3 CANONICAL=A0A8M9PG87-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100006059", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006059", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A494BAC1-1", "protein_name": "Predicted gene, 17266", "gene_name": "Gm17266", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNESRLQSLFFIILPDLHKLCSVQIILSSRVAEIDIRSAQLKMCRQLLLLHEDILTAPVSGILNQISVVMSIPFFKSGRLSAYIEKYGAKMEAPQRVTPAILQNCLSYSLMARLAPAWNRTGHLLVQGTDFLSNAGKQSAVVLDINVTETQVCLSIEVYTIRLPPTELQEFDISQRIIEDFHTNQNAVIERHSILSNWCYILPSMKMGQIINILHTAPPDCPLHSFEDFQRHWDDLYGYKLPEDRRDMKIYCSIYFKMINKRTFTYPLSCIRSQPIQFFPRVDLDGVLKSFLSDLKSKLPHLCGFPIKMTNKPCYYTQELTRPLLQENKVKPSNLTTKKLFRASLTQATLVKPTRALNVTPQSTATEHKVEPAVSQQRSGLFSAACHQSGSFHDRKPSWPLEASQLHLEESQLSRENTQVGSKTLCIQSNRAPAFIPVFKRKSEQVNKNISALSTLKRKQSGVTEPTVLAQETSVTQGGKPTASRKRPNSNIRVLAGNLNQKGSKPLQEKGTEFYDRKKEQPSSDSRQTVYLREARPLSTRAVTQASSNSSAVMKNDVDIHTGGKDNLTSRFITQILGKSHESLKLKSQPHIFESELETEDSQLQQQQLANQVPEADAAEHSPIESKAAHSLRQELCLQASRASTKRRSSAAHQRQSSSKKQVKKLGKSTLGWTFTTLNKGLRLERWLSS", "length": 690 }, "evidence": [ { "id": "MGI:4936900", "url": "https://alliancegenome.org/gene/MGI:4936900#orthology", "database": "AGR" }, { "id": "HGNC:40037", "url": "https://alliancegenome.org/gene/HGNC:40037#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-383", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8L1-1", "protein_name": "Similar to human chromosome 18 open reading frame 63", "gene_name": "C18h18orf63", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNEPKVQSLFFIILPDLHKLCTVQITLSGRVAEIDIRSTQIKMCRQLLLSHEDILTAPVPGILNQISVVMSIPFFKSGRLNAYIEKYEAKMEAPQRVTPAILQNCLSYSLMARLAPAWNRTGHLLVQGRDFLSNMGKQSAVVLDINVTETQVCLSIEVYTIRLPPPELQEFDISQHIIEDFHTNQNAVIERHSILSNWCYILPSMKMGQIINFLHTAPPDCPFHSFEDFQRHWDDLYGYKLPEDCGDMKIYCSIYFKMIDKRTFTYPLSCIRSQPMQFFPRVDLDGVLKSFISDLRLKLPHLCGFPVKMTYKPCYYTQELTRPHLQENKVKPSNLTTKKFFRESLTQATLVKPTRALNFIPQSTAAKHKVEPSVGQQRSGLFSAGCHQPGSFQDRKPYWPLKAPQLHLVESKLTRENTQAENKNLCSQGNRAPPFIPVFKRKSEQVNKNVSALSTLKRKQSGFTEPTTLAQETGATQGGKPSLGAATRKRPNSNIRVLAGNLSQKGSKPLQEKGTEFYDRKKEQPLSDLRQTVHLREARPSCTRAVTQTSRNSVAGVKNNVDIHPGGKDNLTSRFITQILGKSHESLKLKSQPHIFESDLETEDSQLQQQQLANQVQEADAAEHSPIESRAARSRRQTVCLESSRASTKRCSSAAHQRQYSSKTQVSNTAKPKNFLNIAASEYSEGHRLSTRCPALP", "length": 697 }, "evidence": [ { "id": "MGI:4936900", "url": "https://alliancegenome.org/gene/MGI:4936900#orthology", "database": "AGR" }, { "id": "HGNC:40037", "url": "https://alliancegenome.org/gene/HGNC:40037#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68DL7-1", "protein_name": "Uncharacterized protein C18orf63", "gene_name": "C18orf63", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNDSRQQSLFFITLPDLNKLCAVRIILSNKVADTEIRTIQMKMCRQLLFLHQDILTSPVSGILNQIWVVMAIPFYKARKLNAYVEKYGAKMEAPQRVIPVILQNCLSYSFMARLAPAWNRTGHLLIQGRDFLSQMGKQSAVVLNINVTETQVCLSIEACTIRLPAPELKEFEISQSIIKDFHANKHAVIERHSILSNWCYVLPSMKMGQIINIFHAIPAACPFHSYGDFQRHWDALYGYKLPGDCGKIKIYCNIYFKMLGERTFTYPLSCIRSQPMQFFPRVDSEVVLKSFLSDLKSKLPHICGFPIKMTSKPCYYTQELTKPNIQEHKVKPPNLTTKKMLRASLTQATSRKPACAQSLLPCSVAVDHKVELSVSQPTSGIFSALHLQPESVQGRKKSLSIRAPQVHSEVLMPNRGNTQVQHTNLSSQSNITPKFVPVFKNRLLQMNKNTSVLGSPKRKQHDVTQSKLFSLKTSMIQHDKLNLGPAIKNRYSSNIQMQAANNLNQENSRPLQEKNTESSENMTKFPSSRGKSTVSLNKNKQLSNSAVFVVSNNNLGVVKSAVDFQMKGKENLTGKGITQILGKSHGSLKLKRQPHIFESDGETEDPRLLQQQSENQAKEVGTSDHRLIVSKIAHRSKRKLCPESSKTSKKHHSDTVHYGQSSSSKKQILDSDKSKLKKSLIIHNA", "length": 685 }, "evidence": [ { "id": "MGI:4936900", "url": "https://alliancegenome.org/gene/MGI:4936900#orthology", "database": "AGR" }, { "id": "HGNC:40037", "url": "https://alliancegenome.org/gene/HGNC:40037#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-383", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-383#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 429, "end_pos": 431, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PG87", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG87" }, { "id": "PF15813", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15813" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4708", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 279, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 429, "end_pos": 431 }, { "start_pos": 544, "end_pos": 546 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PG91-1", "uniprot_ac": "A0A8M9PG91", "uniprot_id": "A0A8M9PG91_DANRE", "mass": { "chemical_mass": 27113.0, "monoisotopic_mass": 27113.0 }, "refseq": { "ac": "XP_021325938", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325938" }, "gene_names": [ { "name": "LOC108181524", "type": "recommended", "evidence": [ { "id": "A0A8M9PG91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG91" } ] }, { "name": "LOC108181524", "type": "synonym", "evidence": [ { "id": "XP_021325938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325938" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PG91", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG91/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021325938", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325938" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325938" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PG91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG91" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108181524", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG91", "locus": {} } ], "crossref": [ { "id": "A0A8M9PG91", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PG91", "database": "AlphaFoldDB", "categories": [] }, { "id": "108181524", "url": "https://www.ncbi.nlm.nih.gov/gene/108181524", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:108181524", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108181524", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PG91", "url": "https://www.orthodb.org/?gene=A0A8M9PG91", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_021325938", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325938", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PG91", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PG91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG91-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPFSNNEKSARHRAKVNADPVARARYLAKRRESYQRRKREGKTKLSSVTELSKAKQDELRQKWRHYKRSHRMRIHNLSLHSCSELDVNPEWLQNFAPYSPGSEAEESKEVPVSSCSVVKQEPETVEIQWENVNSPPPAVSSDSEPNNAQSSAISITPPIMEKVHCSVKLTMTKLHCLLESKQEKIEALEKQFVTDKATIAGCHISHFWMGWLVRVCPPAVLSEQTAVVLLLTAEGTGGSR", "length": 240, "header": "tr|A0A8M9PG91-1|A0A8M9PG91_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108181524 PE=4 SV=1 CANONICAL=A0A8M9PG91-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PG91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PG91/entry#A0A8M9PG91-1", "sequence": { "sequence": "MPFSNNEKSARHRAKVNADPVARARYLAKRRESYQRRKREGKTKLSSVTELSKAKQDELRQKWRHYKRSHRMRIHNLSLHSCSELDVNPEWLQNFAPYSPGSEAEESKEVPVSSCSVVKQEPETVEIQWENVNSPPPAVSSDSEPNNAQSSAISITPPIMEKVHCSVKLTMTKLHCLLESKQEKIEALEKQFVTDKATIAGCHISHFWMGWLVRVCPPAVLSEQTAVVLLLTAEGTGGSR", "length": 240, "header": "tr|A0A8M9PG91-1|A0A8M9PG91_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108181524 PE=4 SV=1 CANONICAL=A0A8M9PG91-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108181524", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108181524", "resource": "KEGG Pathway" } ], "orthologs": [], 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GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021330367", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330367" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGJ0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGJ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108179569", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGJ0", "locus": {} } ], "crossref": [ { "id": "A0A8M9PGJ0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PGJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "108179569", "url": "https://www.ncbi.nlm.nih.gov/gene/108179569", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001878", "url": 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"cd03590", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03590", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "677740", "url": "https://www.ncbi.nlm.nih.gov/gene/677740", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PGK7", "url": "https://www.orthodb.org/?gene=A0A8M9PGK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22803", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22803", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323809", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323809", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PGK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050311-4", "url": "https://zfin.org/ZDB-GENE-050311-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGSVYENSVFAFSTGNSDENDSQYKGHFSNYRESKREVNTAKWTKVLLIVFAVSLVFALGGLCAVRIQYVSVSAQLSAQETNGTIMSRQLDKLTANFTTVRDHLHINELLMKELTANYSRVKEQLSISEETVRKLSRFNQSSGCAICAIHWTHSGEKCYYFSTVKMNWTQSRDHCVTKGGHLVIITSQAEQEFLTSNVKETHWIGLNDLDTEGRWLWVDNQPLSQTEEFWMKRENGVSEPDNWTKQHVDGEDCASLGHPDGETDFWTDAYCFEEKRFVCEAAAAV", "length": 285, "header": "tr|A0A8M9PGK7-1|A0A8M9PGK7_DANRE Isoform 1 of Immune-related, lectin-like receptor 3 isoform X1 OS=Danio rerio OX=7955 GN=illr3 PE=4 SV=1 CANONICAL=A0A8M9PGK7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PGK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGK7/entry#A0A8M9PGK7-1", "sequence": { "sequence": "MGSVYENSVFAFSTGNSDENDSQYKGHFSNYRESKREVNTAKWTKVLLIVFAVSLVFALGGLCAVRIQYVSVSAQLSAQETNGTIMSRQLDKLTANFTTVRDHLHINELLMKELTANYSRVKEQLSISEETVRKLSRFNQSSGCAICAIHWTHSGEKCYYFSTVKMNWTQSRDHCVTKGGHLVIITSQAEQEFLTSNVKETHWIGLNDLDTEGRWLWVDNQPLSQTEEFWMKRENGVSEPDNWTKQHVDGEDCASLGHPDGETDFWTDAYCFEEKRFVCEAAAAV", "length": 285, "header": "tr|A0A8M9PGK7-1|A0A8M9PGK7_DANRE Isoform 1 of Immune-related, lectin-like receptor 3 isoform X1 OS=Danio rerio OX=7955 GN=illr3 PE=4 SV=1 CANONICAL=A0A8M9PGK7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A1Z8L7-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "CK02422a", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQKSIIFLVLPLCLSSSYSAACEGVESDSQCAAYCYGVLNPCIASMGNLQRRVEACEAAVAIARIALNDRRLDNFGTSTNLQLENQNTSQQLLTHGTAMGRKLEENEIFQQLGSKYYYIEKEEKLNWHDALDKCHKMGGHLASLQSQEELDRFNNQLNGLNRYWIDVTNQFNESEFVSVTKGSKANFLSWADGEPTKDGECVDIRTFNGKTTMNDNSCFANLYFICEKSIEI", "length": 232 }, "evidence": [ { "id": "RGD:1359298", "url": "https://alliancegenome.org/gene/RGD:1359298#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "B0S6P2-1", "protein_name": "Lectin isoform X1", "gene_name": "lectin", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMVMLRSLLLLSLFSMGNAAARRCTRQWSRFGSRCFRYFSVPVNWVTAERNCQLLGGNLVSVQNGMENDFLLSLIPNSERFFIGGYDGEDEENWFWSEGSSFGYTNWCSGEPNNMNTEHCLEINWTSDRCWNNLPCSTEQGYICAKNLDGCS", "length": 152 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B7Z0K3-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG14866", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPAGQQLRLTALVYLALGIALLCNGSDGETRQKYANESLADADDPSPVWSQFLEDYVLSQGSSSSGSQRKSKDLPYMGADMGINGPLSYHSSAYKRPGNNIYITRRIGEAVELEPHLRKPVESQSPIVNPQFRPMTNQMLHQQHQQMQQQQQQQQLQQRQQPGFLQQLFGIGGSGGGGGSGTQQQQHVRPVPLQQQQVQQIAQQHPQQQHLVGGQPTTFRAVSENDLYLLGAIEKLVYRVDYLESRVRRSEQLIYYLMAGNNQKEVKDPCPANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAEFEKVSENEEIMAYLLNQPTHRGRDYWLGGLNPGLLWIWSNSAKPVNPNMNLTSIAMAQKGENSTAANLVDSSEQAAEEATGEDVLNNTVQIEGKGRCLRLSYNAGKHSYVYYGQECTSRHYYICEHEDKTLDNKIKKITRELKLFE", "length": 455 }, "evidence": [ { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" }, { "id": "RGD:1359298", "url": "https://alliancegenome.org/gene/RGD:1359298#orthology", "database": "AGR" }, { "id": "RGD:1359505", "url": "https://alliancegenome.org/gene/RGD:1359505#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZBX0-1", "protein_name": "C-type lectin domain family 4 member K", "gene_name": "Cd207", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVEMKETEVPDAHFTVDKQNISLWPREPPPKQDLTPVLRKPHCICAAFICLALVLVTSIVLQAVFYPRLMGKILDVKSDAQMLRGRVDNISTLGSDLKRERGRVDDAEVQMRIVNTSLGRVRSKILSLEASMKIVSNQLQVLTMNWGEVDNLNAKIPELQKDLDKASALNTKVQGLQNSLENINKLLKEQSDILEMMSRGWKYFMGNFYYFSRTPKTWYSAEQYCISRKAHLTSVSSESEHEFLYKVADGIPHWIGLTKAGSEGDWYWVDQTSFNKEQSRRFWIPGEPNNVRNNEHCANIRVSALKCWNDSPCDNVYSFICKMPYIRMIT", "length": 332 }, "evidence": [ { "id": "FB:FBgn0030050", "url": "https://alliancegenome.org/gene/FB:FBgn0030050#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZXM6-1", "protein_name": "C-type lectin domain family 6, member A, pseudogene 1", "gene_name": "Clec6a-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQERHPQRKGVCWTLRLWSTAVISMLLLSTCFIASCMVTYQFTMEKPNRRLSELHTYHSSLTCCSKGTMVSEKLWGCCPNHWKSFGSSCYLISTKENFWSISEQNYIHMGAHLVVINTETEQNFITQQLNESLSYFLGLSDPQGNSKWQWIDNTPFSQNVRFWHPHEPNLPEEWCASIVYWNPSKWGWNDVFCDSKHNSICETKKIYL", "length": 209 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "RGD:1359505", "url": "https://alliancegenome.org/gene/RGD:1359505#orthology", "database": "AGR" }, { "id": "HGNC:14556", "url": "https://alliancegenome.org/gene/HGNC:14556#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PT25-1", "protein_name": "C-type lectin domain family 4, member A3", "gene_name": "Clec4a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSENIYINTNFKNKYDSSDIDTDFRPDPPKKSKSQKSCHKFSKVLFTSLIIYFLLLTILFSSALIILFKKYSQLLEEKTIMKELNYTELECTKWDSLSEDKVWSCCPKDWKPFDSNCYFPSTDSVESWMESEEKCSGIGAHLVVIHSQEEQDFLPRILDTHAAYFIGLSDPGHRQWQWVDQTPYNGNATFWHEGEPSSDNEQCVIINHHENTGWGWSDSSCSDKQKLVCQVKKIYL", "length": 237 }, "evidence": [ { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7G4-1", "protein_name": "C-type lectin domain family 4, member B2", "gene_name": "Clec4b2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMQEKLPQGKGGCWTLRLWSAAVISMLLLSTCFIMSCVVTYQFMMEKPNRRLSELHTYNSNFTCCSDGTMVSGKVWSCCPKDWKSFGSHCYFTTDFVANWNESKEKCSHMGAHLLVIHSQEEQDFINGILDTRWGYFTGLSDQGQNQWQWIDQTPYNESVTFWHEDEPNNDYEKCVEINHHKDIGWGWNDIVCSSEHKSICQVKKIYL", "length": 208 }, "evidence": [ { "id": "HGNC:13258", "url": "https://alliancegenome.org/gene/HGNC:13258#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P20693-1", "protein_name": "Low affinity immunoglobulin epsilon Fc receptor", "gene_name": "Fcer2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEENEYSGYWEPPRKRCCCARRGTQLMLVGLLSTAMWAGLLALLLLWHWETEKNLKQLGDTAIQNVSHVTKDLQKFQSNQLAQKSQVVQMSQNLQELQAEQKQMKAQDSRLSQNLTGLQEDLRNAQSQNSKLSQNLNRLQDDLVNIKSLGLNEKRTASDSLEKLQEEVAKLWIEILISKGTACNICPKNWLHFQQKCYYFGKGSKQWIQARFACSDLQGRLVSIHSQKEQDFLMQHINKKDSWIGLQDLNMEGEFVWSDGSPVGYSNWNPGEPNNGGQGEDCVMMRGSGQWNDAFCRSYLDAWVCEQLATCEISAPLASVTPTRPTPKSEP", "length": 331 }, "evidence": [ { "id": "FB:FBgn0030050", "url": "https://alliancegenome.org/gene/FB:FBgn0030050#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q59DY5-1", "protein_name": "C-type lectin 37Db", "gene_name": "lectin-37Db", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMVKLLLLFLVCWSALPLESSPLGNRYNLEIGEKQYYISLAKTNWFEASNHCRQNGGFLLNLESREELELLSPHLHPAYSYWLSINDLGERGVYVSEATGLEAPFLNWSAGEPDNSSGYDRCVELWLSTTSFQMNDLPCYSSVAFICQLN", "length": 150 }, "evidence": [ { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q67EQ0-1", "protein_name": "C-type lectin domain family 4 member A", "gene_name": "Clec4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASEITYAEVRIKNESNSSVTYSGSPAAPREKPTRHLSKPGSLLVPFTSLMVLLLLLAITFLVAFIIYFQKYSQFLEEKKAIKGITHKELNCIKNVLLMEEKSWSCCPKNWKPFGSHCYWVTKHTSTYSKASWSESEKNCFSMGAHLLVIHSKEEQDFITGILNRDAAYFIGLWDSGHRQWQWVSQTPYNASATFWHKGEPSSDDEKCVIINHLNSGWGWNDIPCSGKQQSVCQMKKIQL", "length": 240 }, "evidence": [ { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q67EQ1-1", "protein_name": "C-type lectin domain family 4 member E", "gene_name": "Clec4e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNSTKSPASHHTERECFKNSQVLSWTMAGASILFLSVCFITRCVVTYHSFQIYGQKKLQPHKTIKELSCYLEASGSVKNCCPLNWKHFQSSCYFFSTTTLSWLSSLKNCSDMGAHLVVINTWEEQEFLFRTKPRKKEFYIGLTDQVVEGQWRWVDDTPFTESLSFWDAGEPNNIVFVEDCATMRDSSNPRKNWNDVSCFFSMPWICEMPEISPLD", "length": 215 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" }, { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "RGD:1359298", "url": "https://alliancegenome.org/gene/RGD:1359298#orthology", "database": "AGR" }, { "id": "HGNC:14555", "url": "https://alliancegenome.org/gene/HGNC:14555#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q69FH1-1", "protein_name": "C-type lectin domain family 4 member D", "gene_name": "Clec4d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLEESQMKSKGALHPRRIPWVCAVVSISFLSACFISTCVVTHYFLLWKRGSALKFSDYHTRLTCILEEPQPGATGGTWTCCPVSWRAFQSNCYFALNDNQTWHESERNCSGMSSHLVTINTEAEQDFVTQLLDEQFSYFLGLSYEKVEGQWQWVDKTPFNPNVVFWKVGEPKDSMEEDCVVLVYDQDKWVWNDFPCHFEMGRICKLPGATFDWNPSK", "length": 218 }, "evidence": [ { "id": "HGNC:14554", "url": "https://alliancegenome.org/gene/HGNC:14554#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EIG7-1", "protein_name": "C-type lectin domain family 6 member A", "gene_name": "CLEC6A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQEQQPQSTEKRGWLSLRLWSVAGISIALLSACFIVSCVVTYHFTYGETGKRLSELHSYHSSLTCFSEGTKVPAWGCCPASWKSFGSSCYFISSEEKVWSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLNESFSYFLGLSDPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQCASIVFWKPTGWGWNDVICETRRNSICEMNKIYL", "length": 209 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "RGD:1359505", "url": "https://alliancegenome.org/gene/RGD:1359505#orthology", "database": "AGR" }, { "id": "HGNC:14556", "url": "https://alliancegenome.org/gene/HGNC:14556#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8IRH8-1", "protein_name": "Triforce, isoform B", "gene_name": "tfc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIRPTLIVVLISLASVDSGHNSPVTTIPVAEPISQVPHGFQLGQNNHISSSSNISRSGGGNGRDKRGAQLDPSEIARQNQITQQIFANYLERRLFPNRTANQKIPTIADILPKPKPSPRPRPRGFAASDGGNFKRSGGGAQRNRLAAAASKRQSGYNRKRLREEQEEEEEADDQERDQQPLANQEDFDYDVQESLQSVESEQHDQYYGNIFHRDPSENEVDNDCPNCVDESQYTPNKWTMPLLKLGEKRYYLGIFFKANWFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLGHEHFWISGTDLADEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGKGLKWNDSPCSFETYFVCEVQPN", "length": 376 }, "evidence": [ { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8N1N0-1", "protein_name": "C-type lectin domain family 4 member F", "gene_name": "CLEC4F", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGEAVRFCTDNQCVSLHPQEVDSVAMAPAAPKIPRLVQATPAFMAVTLVFSLVTLFVVVQQQTRPVPKPVQAVILGDNITGHLPFEPNNHHHFGREAEMRELIQTFKGHMENSSAWVVEIQMLKCRVDNVNSQLQVLGDHLGNTNADIQMVKGVLKDATTLSLQTQMLRSSLEGTNAEIQRLKEDLEKADALTFQTLNFLKSSLENTSIELHVLSRGLENANSEIQMLNASLETANTQAQLANSSLKNANAEIYVLRGHLDSVNDLRTQNQVLRNSLEGANAEIQGLKENLQNTNALNSQTQAFIKSSFDNTSAEIQFLRGHLERAGDEIHVLKRDLKMVTAQTQKANGRLDQTDTQIQVFKSEMENVNTLNAQIQVLNGHMKNASREIQTLKQGMKNASALTSQTQMLDSNLQKASAEIQRLRGDLENTKALTMEIQQEQSRLKTLHVVITSQEQLQRTQSQLLQMVLQGWKFNGGSLYYFSSVKKSWHEAEQFCVSQGAHLASVASKEEQAFLVEFTSKVYYWIGLTDRGTEGSWRWTDGTPFNAAQNKAPGSKGSCPLRKYIIVNSGMGACSFIDTPPCPWILSN", "length": 589 }, "evidence": [ { "id": "FB:FBgn0030050", "url": "https://alliancegenome.org/gene/FB:FBgn0030050#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8WTT0-1", "protein_name": "C-type lectin domain family 4 member C", "gene_name": "CLEC4C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVPEEEPQDREKGLWWFQLKVWSMAVVSILLLSVCFTVSSVVPHNFMYSKTVKRLSKLREYQQYHPSLTCVMEGKDIEDWSCCPTPWTSFQSSCYFISTGMQSWTKSQKNCSVMGADLVVINTREEQDFIIQNLKRNSSYFLGLSDPGGRRHWQWVDQTPYNENVTFWHSGEPNNLDERCAIINFRSSEEWGWNDIHCHVPQKSICKMKKIYI", "length": 213 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" }, { "id": "HGNC:13258", "url": "https://alliancegenome.org/gene/HGNC:13258#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8WXI8-1", "protein_name": "C-type lectin domain family 4 member D", "gene_name": "CLEC4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLEKPQSKLEGGMHPQLIPSVIAVVFILLLSVCFIASCLVTHHNFSRCKRGTGVHKLEHHAKLKCIKEKSELKSAEGSTWNCCPIDWRAFQSNCYFPLTDNKTWAESERNCSGMGAHLMTISTEAEQNFIIQFLDRRLSYFLGLRDENAKGQWRWVDQTPFNPRRVFWHKNEPDNSQGENCVVLVYNQDKWAWNDVPCNFEASRICKIPGTTLN", "length": 215 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" }, { "id": "HGNC:14554", "url": "https://alliancegenome.org/gene/HGNC:14554#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JKF4-1", "protein_name": "C-type lectin domain family 6 member A", "gene_name": "Clec6a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQERQSQGKGVCWTLRLWSAAVISMLLLSTCFIASCVVTYQFIMDQPSRRLYELHTYHSSLTCFSEGTMVSEKMWGCCPNHWKSFGSSCYLISTKENFWSTSEQNCVQMGAHLVVINTEAEQNFITQQLNESLSYFLGLSDPQGNGKWQWIDDTPFSQNVRFWHPHEPNLPEERCVSIVYWNPSKWGWNDVFCDSKHNSICEMKKIYL", "length": 209 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "RGD:1359505", "url": "https://alliancegenome.org/gene/RGD:1359505#orthology", "database": "AGR" }, { "id": "HGNC:14556", "url": "https://alliancegenome.org/gene/HGNC:14556#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QZ15-1", "protein_name": "C-type lectin domain family 4 member A", "gene_name": "Clec4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASEITYAEVKFKNESNSLHTYSESPAAPREKPIRDLRKPGSPSLLLTSLMLLLLLLAITFLVAFIIYFQKYSQLLEEKKAAKNIMHNELNCTKSVSPMEDKVWSCCPKDWRLFGSHCYLVPTVSSSASWNKSEENCSRMGAHLVVIQSQEEQDFITGILDTHAAYFIGLWDTGHRQWQWVDQTPYEESITFWHNGEPSSGNEKCATIIYRWKTGWGWNDISCSLKQKSVCQMKKINL", "length": 238 }, "evidence": [ { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9R0Q8-1", "protein_name": "C-type lectin domain family 4 member E", "gene_name": "Clec4e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSTKSPASHHTERGCFKNSQVLSWTIAGASILFLSGCFITRCVVTYRSSQISGQNLQPHRNIKELSCYSEASGSVKNCCPLNWKHYQSSCYFFSTTTLTWSSSLKNCSDMGAHLVVIDTQEEQEFLFRTKPKRKEFYIGLTDQVVEGQWQWVDDTPFTESLSFWDAGEPNNIVLVEDCATIRDSSNSRKNWNDIPCFYSMPWICEMPEISPLD", "length": 214 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" }, { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "RGD:1359298", "url": "https://alliancegenome.org/gene/RGD:1359298#orthology", "database": "AGR" }, { "id": "HGNC:14555", "url": "https://alliancegenome.org/gene/HGNC:14555#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULY5-1", "protein_name": "C-type lectin domain family 4 member E", "gene_name": "CLEC4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSSKSSETQCTERGCFSSQMFLWTVAGIPILFLSACFITRCVVTFRIFQTCDEKKFQLPENFTELSCYNYGSGSVKNCCPLNWEYFQSSCYFFSTDTISWALSLKNCSAMGAHLVVINSQEEQEFLSYKKPKMREFFIGLSDQVVEGQWQWVDGTPLTKSLSFWDVGEPNNIATLEDCATMRDSSNPRQNWNDVTCFLNYFRICEMVGINPLNKGKSL", "length": 219 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" }, { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "RGD:1359298", "url": "https://alliancegenome.org/gene/RGD:1359298#orthology", "database": "AGR" }, { "id": "HGNC:14555", "url": "https://alliancegenome.org/gene/HGNC:14555#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9UMR7-1", "protein_name": "C-type lectin domain family 4 member A", "gene_name": "CLEC4A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSEITYAEVRFKNEFKSSGINTASSAASKERTAPHKSNTGFPKLLCASLLIFFLLLAISFFIAFVIFFQKYSQLLEKKTTKELVHTTLECVKKNMPVEETAWSCCPKNWKSFSSNCYFISTESASWQDSEKDCARMEAHLLVINTQEEQDFIFQNLQEESAYFVGLSDPEGQRHWQWVDQTPYNESSTFWHPREPSDPNERCVVLNFRKSPKRWGWNDVNCLGPQRSVCEMMKIHL", "length": 237 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" }, { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VKL8-1", "protein_name": "Lectin-33A", "gene_name": "lectin-33A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCIKGSFGFLLIALILECANAQTCPLPFSRVGNKCYHVSLQEANWHVADRSCRKLGAELMVLDNQEDKLLTTTFLKSMGLSFTQSWHHSVWAGINCLGNRRTFLLARNGETVPYLNWVPLEPNNASPEEDCVGFANYNGAFGYHDIECKVQFPYVCQREPAEDYLCLKRDLFLKVLL", "length": 177 }, "evidence": [ { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VLM0-1", "protein_name": "Lectin-29Ca", "gene_name": "lectin-29Ca", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYKYATCIFSIFALWNFWGVSAKKQDTSTGTNELPKAPMPYYTIENIDMHQQHWFTYNSLRQNGTLWRIGNMEQRLEMRLQSFQNQMETKLRALKQQIEPYMENVKMSNKIKMSVFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFSEETKKKYWVDINSRANDGASWISTLSGRDVPFLKWKPNLATNIHNHCVYINSNEMYFENCANDNYFACQAEQWA", "length": 236 }, "evidence": [ { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "RGD:1359298", "url": "https://alliancegenome.org/gene/RGD:1359298#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VM16-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG15818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFSSTRIILCAFLLLYPYGSLIEAQEGRRYVCLLSDPPNQCSEYCVSALQPVIDHLSKEQQDWGACEVKLNGSVAKLDKIEDQLTATQIQIEAQQAFLVNNISKAIKTEDLEQKLKDIEGNQTALSNQLKDGQKRTENQLTAIQKTLSDIERKLVLQRYQQIGSRYFYIEHNLQVNWRTAEQRCIEMGGHLAAFQNAEEYNAIVGQLNKANYWLGVNDLAKQGEFISLASGKRATYFKWRKNEPKYNNPTQHCAYVFGHENIMIVLSCTTDVMHFICQSDSDV", "length": 283 }, "evidence": [ { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VPS1-1", "protein_name": "Lectin-21Cb", "gene_name": "lectin-21Cb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFKYDTYFLYLIVLLDPQGAQENNCPKVSLSERLEKRGEFSLVEFDPLLKFIVKNPHKELLGEIEGLVGHTENKLQPMKSVIPNQSKALLNYLDLHSKLEYLDAALQKAINSLQCSLKNTKVMSTGKPHPEFQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQLEARWFWLDISNLVDKDQYISLATGKEVSYLKWRHGEPKKSSTANCAYLYAGDYYTYQCSDRNFFICQAV", "length": 249 }, "evidence": [ { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "RGD:1359298", "url": "https://alliancegenome.org/gene/RGD:1359298#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VPS2-1", "protein_name": "Lectin-21Ca", "gene_name": "lectin-21Ca", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFQHANFFLHVFMACGLYGIRAKDVCPRMSTDKEVCLVELAPVLKYISNNHKSHWNSANEVQVNETRKQLAKIEGQEKETNDKIKVIHDNVDNEFNALSAKIKNVKNIQRHLASLELQLQETKKALNLSVEAKKVMPKTEIPSQFQKIGWRHFFIEKKHKVDWFKATSMCHKMGAHLLTIQSEDELDAIRTELKDINDGSHDFWLDINDIAKWGEFISLATGMNPPFLKWHKHRPQVQIHQRCVHLRGGEMMDGKCSEQFLFICQLAVN", "length": 269 }, "evidence": [ { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "RGD:1359298", "url": "https://alliancegenome.org/gene/RGD:1359298#orthology", "database": "AGR" }, { "id": "HGNC:14556", "url": "https://alliancegenome.org/gene/HGNC:14556#orthology", "database": "AGR" }, { "id": "HGNC:13258", "url": "https://alliancegenome.org/gene/HGNC:13258#orthology", "database": "AGR" }, { "id": "HGNC:14555", "url": "https://alliancegenome.org/gene/HGNC:14555#orthology", "database": "AGR" }, { "id": "HGNC:14554", "url": "https://alliancegenome.org/gene/HGNC:14554#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQU4-1", "protein_name": "Lectin-24A", "gene_name": "lectin-24A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFRLSVLVLNLLLVSHEFSAGTAKIEIQPLPALCNGYCFPTLKPVMEYVAIHQDKWNTCTEILANEARKDQIQLNIQLDALKADVSNIKASQLSKDEKLDRMEREQFAMHESLETINRYLTVKLDRTKLQLEAIKNTMDYMKAQMDGYFSAINGVQCLQPGFEKIGDRYFYIEEDVELNWLDAQAKCRRMGGHLASIKTKQEFDAIVEKLDDSKSYFLGVNENTKTGDFVSAASGKSCLYHEWGPGEPHHNNDQERCVSILRKLMHVGNCTYEKRFICQYGI", "length": 282 }, "evidence": [ { "id": "MGI:1861232", "url": "https://alliancegenome.org/gene/MGI:1861232#orthology", "database": "AGR" }, { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "HGNC:13257", "url": "https://alliancegenome.org/gene/HGNC:13257#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQX3-1", "protein_name": "Lectin-24Db", "gene_name": "lectin-24Db", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFRLEKCIVYLLVACNLVESRAESTENSRSVCLLKDPPNQCGEFCLSVLQPLLDHIVKHQEQWNTSEALWLNETQGKLDRIQTQLAAQALSLEESAQKVPGDIKDRLDRMEHLQTTLQESLKKMPAELDARLMKMENQQKTLGDQLENQINLTKESQQDQLEALKNAMPINFEMRLAQIEEQQKLLQETLKKIPEDFERKLQKLEQNQKDELTKLGAQQSANQVTLKEIYTKVFWPKFERIGSRLFYINHKDAYDWQSAVDFCRDMGGYIAAIKDQEELDAISARLDDKSYWLGINDLQSSNTYVSVASGREVEFLNWNAGEPNHGNEDENCVELIRSKMNDDPCHRKKHVICQTDKEV", "length": 359 }, "evidence": [ { "id": "HGNC:14556", "url": "https://alliancegenome.org/gene/HGNC:14556#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W3D8-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG12111", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYRTETLLLILTSVGIPSLAYLPDVNIFTNYRTEVYNGIPSEIDTTPFVRIGDNYYYIEPMNKVNWFQAAGACRMMNAHLASIEDKPEMEALIKYMKAKGFKNNDYFWISGNDLGTEGAFYWMSNGRPMTYAPWNGPKQMPDNYGGNENCVHMFATREMINDANCKIQMLYVCEATEPKTFKFTYIKW", "length": 188 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-050311-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050311-4#orthology", "database": "AGR" }, { "id": "FB:FBgn0030050", "url": "https://alliancegenome.org/gene/FB:FBgn0030050#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z2H6-1", "protein_name": "C-type lectin domain family 4 member D", "gene_name": "Clec4d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLEESQMKSKGTRHPQLIPCVFAVVSISFLSACFISTCLVTHHYFLRWTRGSVVKLSDYHTRVTCIREEPQPGATGGTWTCCPVSWRAFQSNCYFPLNDNQTWHESERNCSGMSSHLVTINTEAEQNFVTQLLDKRFSYFLGLADENVEGQWQWVDKTPFNPHTVFWEKGESNDFMEEDCVVLVHVHEKWVWNDFPCHFEVRRICKLPGITFNWKPSK", "length": 219 }, "evidence": [ { "id": "HGNC:14554", "url": "https://alliancegenome.org/gene/HGNC:14554#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGK7" } ], "pmid": "" }, { "name": "positive regulation of natural killer cell mediated cytotoxicity", "id": "GO:0045954", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045954", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGK7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGK7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGK7" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGK7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 20, "end_pos": 22, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PGK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGK7" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 280, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 20, "end_pos": 22 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 82, "end_pos": 84 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PGP8-1", "uniprot_ac": "A0A8M9PGP8", "uniprot_id": "A0A8M9PGP8_DANRE", "mass": { "chemical_mass": 47334.0, "monoisotopic_mass": 47334.0 }, "refseq": { "ac": "XP_021330452", "name": "5-hydroxytryptamine receptor 3A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330452" }, "gene_names": [ { "name": "LOC101884816", "type": "recommended", "evidence": [ { "id": "A0A8M9PGP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8" } ] }, { "name": "LOC101884816", "type": "synonym", "evidence": [ { "id": "XP_021330452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330452" } ] } ], "protein_names": [ { "name": "5-hydroxytryptamine receptor 3A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021330452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330452" }, { "id": "A0A8M9PGP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021330452.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021330452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330452" } ] }, { "annotation": "Forms serotonin (5-hydroxytryptamine/5-HT3)-activated cation-selective channel complexes, which when activated cause fast, depolarizing responses in neurons.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8#function" }, { "database": "UniProtKB", "id": "ARBA00037540", "url": "https://www.uniprot.org/uniprotkb/ARBA00037540#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101884816", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8", "locus": {} } ], "crossref": [ { "id": "A0A8M9PGP8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PGP8", "database": "AlphaFoldDB", "categories": [] }, { "id": "101884816", "url": "https://www.ncbi.nlm.nih.gov/gene/101884816", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038050", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038050", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101884816", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884816", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PGP8", "url": "https://www.orthodb.org/?gene=A0A8M9PGP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18945", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18945", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02931", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02931", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02932", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02932", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021330452", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330452", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29463", "url": "https://www.rhea-db.org/rhea/29463", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34963", "url": "https://www.rhea-db.org/rhea/34963", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PGP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4F3", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4F3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4F3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4F3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4F4", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4F4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4F4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4F4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4G5", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4G5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J4G5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J4G5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MCLRWLLFALASVGCVSANANCSYEKLIEYLGLNDNNVKLTSLRPVDNWKNHVTVYIDLFVTSITEVNEKAQSISTQVLLAHGWGNDFTTWKPDDFCGMSACSVKKDMVWTPDIVIAESIKTEIATMENAFVRLESRGIVFASNTLAVTSACKMDLHLFPFDTQSCTLTIMSSVHSSDQLQIRPFSDASFLTQSSQKAFQTQGEWELISINMSNNQINFIGDLRDQLIFRITIKRKPVLYVIDFIMPVFCFLILDLASFFVSSGVKEKLGFKVTLLLAISVLLLLLKDMLPSTASDVPLIGMYCVIIFTLIGISVLETIFLSFLMDRGKESASVAPMHRKSALSDAVKSTEGPADSVSDRNEAPLTADALRQIIMEFQVQNQQQKKKSLSWTRVAKIIDLVFFLMYATTVLLFLIVLSIAWFP", "length": 423, "header": "tr|A0A8M9PGP8-1|A0A8M9PGP8_DANRE Isoform 1 of 5-hydroxytryptamine receptor 3A isoform X1 OS=Danio rerio OX=7955 GN=LOC101884816 PE=3 SV=3 CANONICAL=A0A8M9PGP8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PGP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8/entry#A0A8M9PGP8-1", "sequence": { "sequence": "MCLRWLLFALASVGCVSANANCSYEKLIEYLGLNDNNVKLTSLRPVDNWKNHVTVYIDLFVTSITEVNEKAQSISTQVLLAHGWGNDFTTWKPDDFCGMSACSVKKDMVWTPDIVIAESIKTEIATMENAFVRLESRGIVFASNTLAVTSACKMDLHLFPFDTQSCTLTIMSSVHSSDQLQIRPFSDASFLTQSSQKAFQTQGEWELISINMSNNQINFIGDLRDQLIFRITIKRKPVLYVIDFIMPVFCFLILDLASFFVSSGVKEKLGFKVTLLLAISVLLLLLKDMLPSTASDVPLIGMYCVIIFTLIGISVLETIFLSFLMDRGKESASVAPMHRKSALSDAVKSTEGPADSVSDRNEAPLTADALRQIIMEFQVQNQQQKKKSLSWTRVAKIIDLVFFLMYATTVLLFLIVLSIAWFP", "length": 423, "header": "tr|A0A8M9PGP8-1|A0A8M9PGP8_DANRE Isoform 1 of 5-hydroxytryptamine receptor 3A isoform X1 OS=Danio rerio OX=7955 GN=LOC101884816 PE=3 SV=3 CANONICAL=A0A8M9PGP8-1" }, "locus": {} }, { "isoform_ac": "A0AC58J4F3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8/entry#A0AC58J4F3-1", "sequence": { "sequence": "MKKPRASRHKSYLHTIKTEIATMENAFVRLESRGIVFASNTLAVTSACKMDLHLFPFDTQSCTLTIMSSVHSSDQLQIRPFSDASFLTQSSQKAFQTQGEWELISINMSNNQINFIGDLRDQLIFRITIKRKPVLYVIDFIMPVFCFLILDLASFFVSSGVKEKLGFKVTLLLAISVLLLLLKDMLPSTASDVPLIGMYCVIIFTLIGISVLETIFLSFLMDRGKESASVAPMHRKSALSDAVKSTEGPADSVSDRNEAPLTADALRQIIMEFQVQNQQQKKKSLSWTRVAKIIDLVFFLMYATTVLLFLIVLSIAWFP", "length": 319, "header": "tr|A0AC58J4F3-1|A0AC58J4F3_DANRE Computationally mapped isoform of 5-hydroxytryptamine receptor 3C isoform X3 OS=Danio rerio OX=7955 GN=LOC101884816 PE=4 SV=1 CANONICAL=A0A8M9PGP8-1" }, "locus": {} }, { "isoform_ac": "A0AC58J4F4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8/entry#A0AC58J4F4-1", "sequence": { "sequence": "MKKPRASRHKSYLHTIKTEIATMENAFVRLESRGDQLQIRPFSDASFLTQSSQKAFQTQGEWELISINMSNNQINFIGDLRDQLIFRITIKRKPVLYVIDFIMPVFCFLILDLASFFVSSGVKEKLGFKVTLLLAISVLLLLLKDMLPSTASDVPLIGMYCVIIFTLIGISVLETIFLSFLMDRGKESASVAPMHRKSALSDAVKSTEGPADSVSDRNEAPLTADALRQIIMEFQVQNQQQKKKSLSWTRVAKIIDLVFFLMYATTVLLFLIVLSIAWFP", "length": 280, "header": "tr|A0AC58J4F4-1|A0AC58J4F4_DANRE Computationally mapped isoform of 5-hydroxytryptamine receptor 3A isoform X4 OS=Danio rerio OX=7955 GN=LOC101884816 PE=4 SV=1 CANONICAL=A0A8M9PGP8-1" }, "locus": {} }, { "isoform_ac": "A0AC58J4G5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8/entry#A0AC58J4G5-1", "sequence": { "sequence": "MCLRWLLFALASVGCVSANANCSYEKLIEYLGLNDNNVKLTSLRPVDNWKNHVTVYIDLFVTSITEVNEKAQSISTQVLLAHGWGNDFTTWKPDDFCGMSACSVKKDMVWTPDIVIAESIKTEIATMENAFVRLESRGDQLQIRPFSDASFLTQSSQKAFQTQGEWELISINMSNNQINFIGDLRDQLIFRITIKRKPVLYVIDFIMPVFCFLILDLASFFVSSGVKEKLGFKVTLLLAISVLLLLLKDMLPSTASDVPLIGMYCVIIFTLIGISVLETIFLSFLMDRGKESASVAPMHRKSALSDAVKSTEGPADSVSDRNEAPLTADALRQIIMEFQVQNQQQKKKSLSWTRVAKIIDLVFFLMYATTVLLFLIVLSIAWFP", "length": 384, "header": "tr|A0AC58J4G5-1|A0AC58J4G5_DANRE Computationally mapped isoform of 5-hydroxytryptamine receptor 3A isoform X2 OS=Danio rerio OX=7955 GN=LOC101884816 PE=4 SV=1 CANONICAL=A0A8M9PGP8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101884816", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884816", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "transmembrane signaling receptor activity", "id": "GO:0004888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004888", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8" } ], "pmid": "" }, { "name": "extracellular ligand-gated monoatomic ion channel activity", "id": "GO:0005230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005230", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGP8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29463", "name": "", "equation": "K(+)(in) = K(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AB32T5S6-1", "A0AC58II33-1" ], "evidence": [ { "id": "29463", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29463" } ] }, { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8M9Q2T2-1", "A0AC58II33-1", "A0AC58HSD6-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] }, { "id": "34963", "name": "", "equation": "Na(+)(in) = Na(+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AC58II33-1" ], "evidence": [ { "id": "34963", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34963" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8M9Q2T2", "gene_name": "trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2T2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9Q2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2T2" } ] } ] }, { "uniprot_ac": "A0AB32T5S6", "gene_name": "kcnk4a", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AB32T5S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T5S6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AB32T5S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AB32T5S6" } ] } ] }, { "uniprot_ac": "A0AC58HSD6", "gene_name": "trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58HSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HSD6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58HSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HSD6" } ] } ] }, { "uniprot_ac": "A0AC58II33", "gene_name": "pycr1a", "activity": [ { "ec_number": "1.5.1.2", "activity": "L-proline + NAD(+) = (S)-1-pyrroline-5-carboxylate + NADH + 2 H(+).", "evidence": [ { "id": "A0AC58II33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58II33" } ] }, { "ec_number": "1.5.1.2", "activity": "", "evidence": [ { "id": "A0AC58II33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58II33" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PGP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8" }, { "id": "PF02931", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02931" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Neurotransmitter-gated ion-channel ligand-binding", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 237, "start_aa": "Ser", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PGP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGP8" }, { "id": "PF02932", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02932" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Neurotransmitter-gated ion-channel transmembrane", "eco_id": "ECO_0000259", "start_pos": 245, "end_pos": 344, "start_aa": "Ile", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 211, "end_pos": 213 }, { "start_pos": 21, "end_pos": 23 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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:: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323884.2. 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PGZ7-1", "uniprot_ac": "A0A8M9PGZ7", "uniprot_id": "A0A8M9PGZ7_DANRE", "mass": { "chemical_mass": 22360.0, "monoisotopic_mass": 22360.0 }, "refseq": { "ac": "XP_021326238", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326238" }, "gene_names": [ { "name": "LOC110438376", "type": "recommended", "evidence": [ { "id": "A0A8M9PGZ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGZ7" } ] }, { "name": "LOC110438376", "type": "synonym", "evidence": [ { "id": "XP_021326238", 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record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326238" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PGZ7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGZ7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438376", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGZ7", "locus": {} } ], "crossref": [ { "id": "A0A8M9PGZ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PGZ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd17039", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17039", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": 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"evidence": [ { "id": "XP_005174467", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174467" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_005174467.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005174467", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174467" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PH10", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH10" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438146", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PH10", "locus": {} } ], "crossref": [ { "id": "A0A8M9PH10", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PH10", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438146", "url": "https://www.ncbi.nlm.nih.gov/gene/110438146", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100334495", "url": 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"sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PHE9-1", "uniprot_ac": "A0A8M9PHE9", "uniprot_id": "A0A8M9PHE9_DANRE", "mass": { "chemical_mass": 418746.0, "monoisotopic_mass": 418746.0 }, "refseq": { "ac": "XP_068073649", "name": "zinc finger protein 469", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073649" }, "gene_names": [ { "name": "znf469", "type": "recommended", "evidence": [ { "id": "A0A8M9PHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHE9" } ] }, { "name": "znf469", "type": "synonym", "evidence": [ { "id": "XP_068073649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073649" } ] } ], "protein_names": [ { "name": "Zinc finger protein 469", "type": "synonym", "evidence": [ { "id": "A0A8M9PHE9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHE9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 469", "type": "synonym", "evidence": [ { "id": "XP_068073649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073649" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068073649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073649" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PHE9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHE9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "znf469", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHE9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-LINCRNAG-131125-49", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-LINCRNAG-131125-49", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "101886729", "url": "https://www.ncbi.nlm.nih.gov/gene/101886729", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101886729", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886729", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PHE9", "url": "https://www.orthodb.org/?gene=A0A8M9PHE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21465:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21465:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_068073649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068073649", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PHE9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PHE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHE9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTEETKQSLAAKDLDNESKKKEKGAVEQKKSPEHFQNVSLAPQAVNNLAKFTEKERDNTQQREAVIRPQQAGKIDFKSLQNHSFSSNRTWPSSKDSPQSPNGKNRNRDKTRKSGKGERGSPQQLYRLSITNQRSNPTIGIAYPQQKVSPPKKLESNRGPVSGSYRFHVPSIPEREAELQQEELQFRCFQEGSPNLTSQSYTSQSAGTTSVGPTHQNPPSASQQQQQKPSSTDSNNTQPVINETLFPDFHLNETDTWHSSERTFRNTSFGISSQKSNNLVDLNKANSSFIPMPFQYGYPLLDESASDSFPCDRTTQSQDFIDISLTPNQVSQNSFSFPSSSEGHEAMQTNSQFGNDQVEDRQSYQMHPKPPQYMQTPLGMSSSVASNDEISVSSTHHSEQRKNITDKADAFTPVESRETGFAAAGKRGCHLKNGTTSQRVLVQGSVHQIRNAAQGSSSQLHVISPPHNSIHINPGPLDKSGSKHHGRVSQLWEGPNKVFPPPLTDQTSTPYNFQYQPAPEQRQNTGINGRIPWQQIRFTTALPSQNRIDLSRQLSNQQLTFMIGPSDWQEDSKAHNQKDSNSFLSKKTNEVFSNQRKESGKQGCNTIPPCPFTNKVDMNQGQVGDGKNKSVYFGINHSVPVTPSRNCSYPPLQVGPLGLKMVSPYDSPSHSPSQNPTSSSTCSSLSPASTNSVNSNADDSQMSKGLSPTFYKQQQDKALISSNNMNTHQHHFLSEGSRGLHFKQEKAKENTASFMTHNRLSKPNTDNGKGCLETYRTETHPPPSYSAHQLATSLVSANLDQLDVLLTCKQCDQNFNNLVSFLDHKQYCGQHAFAHNELKDAPKVEDTRKFQTDHTKAMSSGSSYTILRSSSDLHLSLLGLNKNGEIVSDNETKGEIKDDPMKLLLPSAPLPDLEMEDPKLDSLITEALNGLGYQSDNTEIDSSFIDAFVDDDLTTTKCTSTRPALTTKDSTIFEGRTNNETTCSEKPQVCCKYPFDSDLDSLRSDKQTDSPFKESQHEQKQGLKTESSSSESKLQESNCTQIEWEARKSEQTGQENDYSSKFLLSSKFSARCGLKSLQSSTSLVKATCSRSTCANNSPTSQKPIATEGKRKRTGGGSWSKELIHKIVQQKNKLHKLHVKGTKNMQFSLVMERVTPAVQNPTFREYDYVSDSDDDCEPVKIASQGRLSQSIRCKYTYTKECKGRIRADKSRESSWKQNKNECFDPKRDLDVSSSLLKDNPRQRLRRRSSRSSTSSELSTSISICSDSISSPKSTDHTDSDSEKQIEVQRKDQDSLEQNAYEESPSRIRKESSTSLALTFTKNTKRYSTDKILLTEHKDRFTTSKCSSIICKTEETASEHTMTKSTVSLARFKTTRVEIEGKGDHYGFEAGILATKEEPFKTDCPNIITSPRRSSIALNPTETTNNRDSCNRDVFQLKKDAATSKSKSHKKRTNSSECSTPIFEKTHTSTEEASRSSNELFQPKPSLCNSLMNKVCLSPSKTNEDPTEKNGQCLIPYPSEHDQSLSFDTMFGDISVGGFENNLYPDIQLAKVSFSPLESTPDKKELFESSFSPFLEQRDWNLMDVNPVLPDEISQYKEDSDSTENNNHFNHVPFALPEKLMDYTPNLNSSVSVDDLEIKRIVTELESQLQTAKLSSPPSLDNEPPKHLTMSKFSPLRLDPESEDENSSLEINCSSENLEIARPVESHLALFSEPELPWSSPLPFGLMCGQQGLHTPTHSSTINTPNDSGHDHLDLKDSMRLTDLTSENSSSLHLDNKTENNGLEKSEEMLEHEIYTENLMKSLEVISDSLSSGFTSPQSSPNQECVVSEEHEKQDNEHPECKEPEHMESINTEAELSKFSVETNTFSDKPDETTSEISGSLNETKASLIETINDSLHKEELVANEKLLAGTSFESPETTHCVNSNESDSQKSYEHKCESSVNQNKNAEFETQLHIKDSMYTTQNTDVSKTSNFSASPATPKDANTQCVDKIQKCDEDSALIAKPELISEGNGHISDKTGRTTDSLCDADIQPTLLNIKSPLCQDHLPIYSQVINTQQVVSPKHLPVVQDEHGCADIGAITDMTLFTGHSECEDNHQKNKEHRTQAPQFSHNSIQSPCELRDVQLPDTVAPTMSEYIPSLEDGNSDHINIGRSVDTLQSATTEEDDSFIPHLDLEEITTSKLSSPGTLLAVDSISKQTFGETPEQSGALGCSQGAPYDLKPIPINYSDACFNDNSFPSKCLDEENGQSVVKSNSTDSYILNACAFSLDKPLMPSLPHNSNEQTNIQNHLTGLNIPENSINGNHQNENECVSASCSNCCEVTTSDPEQTSKFNHNDMNRIHVPAETIIYMDTHHKPLKNLDSEKMDNQVITSEHDETQRSTTLDVKKTSTTLIPCANAASMALAFASVQNDVQSSKSSETKMSPKKGGAQIELQGKFQCEICAMFFRTQPGLKRHKAMKHVVKSEGILPIENANMSSQIYIPIYNMSHPTEKTMKDGMNIESPAVLSHPNRIEISDGQQINTPCILERTASKADVSTVQGSSDGDQASPVNEITKHSITTMDISSEMFAPNLVKQDIFSDEILNRLKTNILQAVSPDFPSAVQQNCPKSPEKQVNGSNQSYHELSVIKEQGSTEVQKEDTTSTEHSKVHTKEDASDIDSVVKCCDMNPNGVTEDIHFPHGNSFVNIKCENTYSPTEECDTLNGIGSDLKAFFDDESTFSQLFPRNDDRKRKKCARVYGKSNKKQKQLSCLVLDYPPTDAFIDTYKGTKENEMGHVFTSDTNDPCDYETISYDNTKILEMTPRNSAENACQINDGQLDQQTGYEDNLETRMKEFSCESQRTVQQPLQHQGDSHDCSVSENTVSTVPQEGCKLEVSAAACPLQMVCVQENTSHLSNSEMSQLDSTIHISTPYFEPDRDAPSVTTISSTEIKEPERPCKKPVQRKYRKRTDPALKPKDKQYKCKVCFTWFLTLGELDFHKLSHNPSPPPTCYMCVQRKFSSREQLRDHLREKHGKNKAGVWTCGMCLKEISDVWMYNEHLREHATQFARRGQSQSSLLGMPGCFMQENAVKNFISSIMQHRPSRPAKEDIVKPSNKEERRMSLDRQEPSGMRELDSTNLKTISFGGGSKHCALTSLEVLPQAETSAKNADMHPNCKDPSRDCHHCGKQFPKPFKLQRHLVVHNMQKIFLCHKCPVSYQEAKELKHHLQNEHEETDEPHSKHTTLYTCELCADVMHVIKKSFICSTCNYTFSKKEQFDRHMEKHLAEGNKIFKFRGVVRPCKPFNSNYDTSDMPPSKKRKGTESNVDITMSHMQDDNSALPIIDDTAENISEERSTEANSTSVKIEDVVEDFPEAAMELRECTVQTDSAEQGLPSTELKEENESSSLSHEIQKDEPREVSEIDKEALTEICDVKIEDDCCTSPTKLFISETSIAKHIQNTLDTNSSVNLENGSEQGEISDSTLCTLQVGGQSEISLQKKGLSSSGDFELPSVKQSSNEASYLKQDQQTEASFPMKKNESKEQLPTAQAKHITMVKAEETLKQTPDNTLRCLSSADSTHHTNSSNTSEDKDSNKQQKKRKEPKTAHSSQRTPSPTARENLSVNPRVRKKFRPSRCENIDGQRKNDFPNDYPVLTSVKDDTASNKIISKHKIGSSNLGLHLKKVSVDSFPPKKVEIVRHFNGDCKGKKNIPKKAIHSPTPRISNLNNSFNHKSRPKPGVRSIETHTYRTAESQNNLLSQLFGQRLTSFKIPLRKDTSESIN", "length": 3750, "header": "tr|A0A8M9PHE9-1|A0A8M9PHE9_DANRE Isoform 1 of Zinc finger protein 469 OS=Danio rerio OX=7955 GN=znf469 PE=4 SV=1 CANONICAL=A0A8M9PHE9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PHE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHE9/entry#A0A8M9PHE9-1", "sequence": { "sequence": "MTEETKQSLAAKDLDNESKKKEKGAVEQKKSPEHFQNVSLAPQAVNNLAKFTEKERDNTQQREAVIRPQQAGKIDFKSLQNHSFSSNRTWPSSKDSPQSPNGKNRNRDKTRKSGKGERGSPQQLYRLSITNQRSNPTIGIAYPQQKVSPPKKLESNRGPVSGSYRFHVPSIPEREAELQQEELQFRCFQEGSPNLTSQSYTSQSAGTTSVGPTHQNPPSASQQQQQKPSSTDSNNTQPVINETLFPDFHLNETDTWHSSERTFRNTSFGISSQKSNNLVDLNKANSSFIPMPFQYGYPLLDESASDSFPCDRTTQSQDFIDISLTPNQVSQNSFSFPSSSEGHEAMQTNSQFGNDQVEDRQSYQMHPKPPQYMQTPLGMSSSVASNDEISVSSTHHSEQRKNITDKADAFTPVESRETGFAAAGKRGCHLKNGTTSQRVLVQGSVHQIRNAAQGSSSQLHVISPPHNSIHINPGPLDKSGSKHHGRVSQLWEGPNKVFPPPLTDQTSTPYNFQYQPAPEQRQNTGINGRIPWQQIRFTTALPSQNRIDLSRQLSNQQLTFMIGPSDWQEDSKAHNQKDSNSFLSKKTNEVFSNQRKESGKQGCNTIPPCPFTNKVDMNQGQVGDGKNKSVYFGINHSVPVTPSRNCSYPPLQVGPLGLKMVSPYDSPSHSPSQNPTSSSTCSSLSPASTNSVNSNADDSQMSKGLSPTFYKQQQDKALISSNNMNTHQHHFLSEGSRGLHFKQEKAKENTASFMTHNRLSKPNTDNGKGCLETYRTETHPPPSYSAHQLATSLVSANLDQLDVLLTCKQCDQNFNNLVSFLDHKQYCGQHAFAHNELKDAPKVEDTRKFQTDHTKAMSSGSSYTILRSSSDLHLSLLGLNKNGEIVSDNETKGEIKDDPMKLLLPSAPLPDLEMEDPKLDSLITEALNGLGYQSDNTEIDSSFIDAFVDDDLTTTKCTSTRPALTTKDSTIFEGRTNNETTCSEKPQVCCKYPFDSDLDSLRSDKQTDSPFKESQHEQKQGLKTESSSSESKLQESNCTQIEWEARKSEQTGQENDYSSKFLLSSKFSARCGLKSLQSSTSLVKATCSRSTCANNSPTSQKPIATEGKRKRTGGGSWSKELIHKIVQQKNKLHKLHVKGTKNMQFSLVMERVTPAVQNPTFREYDYVSDSDDDCEPVKIASQGRLSQSIRCKYTYTKECKGRIRADKSRESSWKQNKNECFDPKRDLDVSSSLLKDNPRQRLRRRSSRSSTSSELSTSISICSDSISSPKSTDHTDSDSEKQIEVQRKDQDSLEQNAYEESPSRIRKESSTSLALTFTKNTKRYSTDKILLTEHKDRFTTSKCSSIICKTEETASEHTMTKSTVSLARFKTTRVEIEGKGDHYGFEAGILATKEEPFKTDCPNIITSPRRSSIALNPTETTNNRDSCNRDVFQLKKDAATSKSKSHKKRTNSSECSTPIFEKTHTSTEEASRSSNELFQPKPSLCNSLMNKVCLSPSKTNEDPTEKNGQCLIPYPSEHDQSLSFDTMFGDISVGGFENNLYPDIQLAKVSFSPLESTPDKKELFESSFSPFLEQRDWNLMDVNPVLPDEISQYKEDSDSTENNNHFNHVPFALPEKLMDYTPNLNSSVSVDDLEIKRIVTELESQLQTAKLSSPPSLDNEPPKHLTMSKFSPLRLDPESEDENSSLEINCSSENLEIARPVESHLALFSEPELPWSSPLPFGLMCGQQGLHTPTHSSTINTPNDSGHDHLDLKDSMRLTDLTSENSSSLHLDNKTENNGLEKSEEMLEHEIYTENLMKSLEVISDSLSSGFTSPQSSPNQECVVSEEHEKQDNEHPECKEPEHMESINTEAELSKFSVETNTFSDKPDETTSEISGSLNETKASLIETINDSLHKEELVANEKLLAGTSFESPETTHCVNSNESDSQKSYEHKCESSVNQNKNAEFETQLHIKDSMYTTQNTDVSKTSNFSASPATPKDANTQCVDKIQKCDEDSALIAKPELISEGNGHISDKTGRTTDSLCDADIQPTLLNIKSPLCQDHLPIYSQVINTQQVVSPKHLPVVQDEHGCADIGAITDMTLFTGHSECEDNHQKNKEHRTQAPQFSHNSIQSPCELRDVQLPDTVAPTMSEYIPSLEDGNSDHINIGRSVDTLQSATTEEDDSFIPHLDLEEITTSKLSSPGTLLAVDSISKQTFGETPEQSGALGCSQGAPYDLKPIPINYSDACFNDNSFPSKCLDEENGQSVVKSNSTDSYILNACAFSLDKPLMPSLPHNSNEQTNIQNHLTGLNIPENSINGNHQNENECVSASCSNCCEVTTSDPEQTSKFNHNDMNRIHVPAETIIYMDTHHKPLKNLDSEKMDNQVITSEHDETQRSTTLDVKKTSTTLIPCANAASMALAFASVQNDVQSSKSSETKMSPKKGGAQIELQGKFQCEICAMFFRTQPGLKRHKAMKHVVKSEGILPIENANMSSQIYIPIYNMSHPTEKTMKDGMNIESPAVLSHPNRIEISDGQQINTPCILERTASKADVSTVQGSSDGDQASPVNEITKHSITTMDISSEMFAPNLVKQDIFSDEILNRLKTNILQAVSPDFPSAVQQNCPKSPEKQVNGSNQSYHELSVIKEQGSTEVQKEDTTSTEHSKVHTKEDASDIDSVVKCCDMNPNGVTEDIHFPHGNSFVNIKCENTYSPTEECDTLNGIGSDLKAFFDDESTFSQLFPRNDDRKRKKCARVYGKSNKKQKQLSCLVLDYPPTDAFIDTYKGTKENEMGHVFTSDTNDPCDYETISYDNTKILEMTPRNSAENACQINDGQLDQQTGYEDNLETRMKEFSCESQRTVQQPLQHQGDSHDCSVSENTVSTVPQEGCKLEVSAAACPLQMVCVQENTSHLSNSEMSQLDSTIHISTPYFEPDRDAPSVTTISSTEIKEPERPCKKPVQRKYRKRTDPALKPKDKQYKCKVCFTWFLTLGELDFHKLSHNPSPPPTCYMCVQRKFSSREQLRDHLREKHGKNKAGVWTCGMCLKEISDVWMYNEHLREHATQFARRGQSQSSLLGMPGCFMQENAVKNFISSIMQHRPSRPAKEDIVKPSNKEERRMSLDRQEPSGMRELDSTNLKTISFGGGSKHCALTSLEVLPQAETSAKNADMHPNCKDPSRDCHHCGKQFPKPFKLQRHLVVHNMQKIFLCHKCPVSYQEAKELKHHLQNEHEETDEPHSKHTTLYTCELCADVMHVIKKSFICSTCNYTFSKKEQFDRHMEKHLAEGNKIFKFRGVVRPCKPFNSNYDTSDMPPSKKRKGTESNVDITMSHMQDDNSALPIIDDTAENISEERSTEANSTSVKIEDVVEDFPEAAMELRECTVQTDSAEQGLPSTELKEENESSSLSHEIQKDEPREVSEIDKEALTEICDVKIEDDCCTSPTKLFISETSIAKHIQNTLDTNSSVNLENGSEQGEISDSTLCTLQVGGQSEISLQKKGLSSSGDFELPSVKQSSNEASYLKQDQQTEASFPMKKNESKEQLPTAQAKHITMVKAEETLKQTPDNTLRCLSSADSTHHTNSSNTSEDKDSNKQQKKRKEPKTAHSSQRTPSPTARENLSVNPRVRKKFRPSRCENIDGQRKNDFPNDYPVLTSVKDDTASNKIISKHKIGSSNLGLHLKKVSVDSFPPKKVEIVRHFNGDCKGKKNIPKKAIHSPTPRISNLNNSFNHKSRPKPGVRSIETHTYRTAESQNNLLSQLFGQRLTSFKIPLRKDTSESIN", "length": 3750, "header": "tr|A0A8M9PHE9-1|A0A8M9PHE9_DANRE Isoform 1 of Zinc finger protein 469 OS=Danio rerio OX=7955 GN=znf469 PE=4 SV=1 CANONICAL=A0A8M9PHE9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 641, "start_aa": "Thr", "end_pos": 641, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr641", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101886729", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886729", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "substantia propria of cornea development", "id": "GO:1903701", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903701", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PHE9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHE9" } ], "pmid": "" }, { "name": "cornea development in camera-type eye", "id": "GO:0061303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061303", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PHE9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHE9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PHE9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHE9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1037, "end_pos": 1039, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1094, "end_pos": 1096, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1451, "end_pos": 1453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1625, "end_pos": 1627, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1683, "end_pos": 1685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1689, "end_pos": 1691, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1743, "end_pos": 1745, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1765, "end_pos": 1767, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1773, "end_pos": 1775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1879, "end_pos": 1881, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1890, "end_pos": 1892, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1922, "end_pos": 1924, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1969, "end_pos": 1971, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2221, "end_pos": 2223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2249, "end_pos": 2251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2469, "end_pos": 2471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2480, "end_pos": 2482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2610, "end_pos": 2612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2613, "end_pos": 2615, "annotation": "n_glycosylation_sequon" }, { "start_pos": 265, "end_pos": 267, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2883, "end_pos": 2885, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3239, "end_pos": 3241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3320, "end_pos": 3322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3330, "end_pos": 3332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3373, "end_pos": 3375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3435, "end_pos": 3437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3442, "end_pos": 3444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3508, "end_pos": 3510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3552, "end_pos": 3554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3555, "end_pos": 3557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3589, "end_pos": 3591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3695, "end_pos": 3697, "annotation": 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"end_pos": 874, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 291 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1437, "end_pos": 1439 }, { "start_pos": 1476, "end_pos": 1478 }, { "start_pos": 1488, "end_pos": 1490 }, { "start_pos": 167, "end_pos": 169 }, { "start_pos": 184, "end_pos": 186 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 574, "end_pos": 576 }, { "start_pos": 608, "end_pos": 610 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { 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"site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PHT1-1", "uniprot_ac": "A0A8M9PHT1", "uniprot_id": "A0A8M9PHT1_DANRE", "mass": { "chemical_mass": 286300.0, "monoisotopic_mass": 286300.0 }, "refseq": { "ac": "NP_001429408", "name": "leucine rich repeat containing 66 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429408" }, "gene_names": [ { "name": "lrrc66", "type": "recommended", "evidence": [ { "id": "A0A8M9PHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHT1" } ] }, { "name": "lrrc66", "type": "synonym", "evidence": [ { "id": "NP_001429408", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429408" } ] }, { "name": "si:ch73-378d19.3", "type": "synonym", "evidence": [ { "id": "NP_001429408", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429408" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 66", "type": "synonym", "evidence": [ { "id": "A0A8M9PHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHT1/entry#names_and_taxonomy" } ] }, { "name": "leucine rich repeat containing 66 precursor", "type": "synonym", "evidence": [ { "id": "NP_001429408", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429408" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01025451.1, GDQH01002262.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476768, SAMEA4476774 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1. On Aug 8, 2025 this sequence version replaced XP_021324294.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001429408", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429408" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHT1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "lrrc66", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHT1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-240", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-240", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PHT1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PHT1", "database": "AlphaFoldDB", "categories": [] }, { "id": "101882481", "url": "https://www.ncbi.nlm.nih.gov/gene/101882481", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000483", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000483", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101882481", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882481", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PHT1", "url": "https://www.orthodb.org/?gene=A0A8M9PHT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24373", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24373", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24373:SF390", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24373:SF390", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001429408", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429408", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PHT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-240", "url": "https://zfin.org/ZDB-GENE-070705-240", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSASRLVFGVAVLLLQLWGTRCFPSSACPIPCLCQPGPVLNCSSLGLNKAPSWIPESAVSLNISNNALSSLAPLSFGHVKLKGLLHLWVGSNGLESLSLILGPGTRTLSSAEQECSSWAPDLQLLSAERNHLKRLPNGLGCIKSLQILQLSYNQISVISLSDLDNCSHLKELHLQHNSITTIHPHAFKDLQQLKVLDLSYNLLVTVPVPAYQSLRNLDALVDVSFNRWKCDCNLQTLRKWMSFDTEMGHASWKVVCASPPHHAGKDLLYLNDSELTCPTYEHRTSGHYHNMIVKEGMQISIPCRNHSQGIMQVRWWTPQGQEKDNQPELLIKDITEQHAGLYICITGVQGEHISVFDLHVYKKGGGSRLRREAGVILDEKGNVILPKNPAVRVGSRTESEFILAVCLSVIITFILAFILGVVLRPLLDKLWRRIRSKRQSTSSPTSSTEPQPYVNEGYCDVEDHDREVRVGSRVTFGEVTEVQDQMPYYVTVDEDQADGSSESNTESGGLYEDVENNRSSVTDEKQQTLEMERHRGRADSSGSSSLQEGEVNALVVNGQKLPPSSMEDMEFEPIPDETEITRIKRRDSSSASSHSSQEVTLSSEIKHSTEQSVDPSPVAKSEIPGFIKEPFSEWPVRLKEQNVDELDPEMWNDSGESFSFNEDSERSSIHDLSSPALGHPLKDDDKWRQIKVASPSNKINIDSDDDFEKPFGKEVLVDGGKQFEFSDNGSSCNSSQSGESVGGPNNYTVNPELEEIVDESDTGNGANVVNLNRFGTLEDPTFRETMPSAGILIRQETIILEPSDIHLTFTHGNSVDEGMLTDDSSMSSLMNIPHQSGQFADIGIDTVPKDKRYVEFKSSKSHSGSPPLSPSSQKNNILSKEHLISEAHTGASFEDNSSLMQRQVSPDNIQKVKRYIGFNPSDPHTQTLPSPSLTKKDALLETKRYSLSSDDDAQLTTKDDKSFLTTSIPSDVSKVKRYISFKQFDTSSPTLPLSKSETTTEATIQNLQPSSSQNVKEHMFFKQHESHSTSLPSSPTSTRKGLSGKKSKSKKRNDQSFYGSHENLPLYHVHPSYRSSINRLNRGYDTDISFSSEDEDQFIEYPRKLEITTAPGLNGGSIKPGKSKDNVLNIDFDNSSSSTDVFEKKRSKGLMRLKALGARLFNRNENETDVMMSPADWDAGRTGGVSVNKQSKLTKKQTTDDDVIFGKSLSFDHLPKVKRYIQFSHSYPQAQLPSPPPTTSTITPDFKVTTESRTSSFSSEDDFKPTTEDETFGGQVDASFDRLPKVKRYIQFSHVEPYSTTLPLKGSPELVVQPESRRSSTSSDDNDIKPNEDSFFSQIGVSFDSVPHVKRYIQFNQPKPYSPTQTSSPISIKRPAVEVETSSSTSVKSDDKSDATGNWGQIDLNAVPKVKRYVQFTEFKDSSTPPLVSSSSTKVTTEMEIKTESTIERFPKDQENLTQAEVSFLENIPKVKRYIHFKQSEPHPTTSDTLHVTPEMIIKSETRRSSTSSEEDIKLTKNEGHVLEETVTSLNSVPRVKRYIQFTYPESQPLTQVSSERVNTSVVEKETRRWSTSSEEDVKPATKENFGETEEYHFQIPKVKRYIKFTEAEPYSSPLSPIPPAITVKETEKEFKPPANRESTSSENHDQEQIGVSLDKVPSVKRYIQFTHPEYQYPSQTSTSLLSESVSIPAVDKETRRWSTSSEEDVKPPTEDIKETDEYLIQIPKVKRYIKFTPSEPHSSAPKQDSPVKSISVTETELKQPVIKENSSTKDVVQEDNVSGQIGVSLDGVPRVKRYIAFTHPETSTAFSDERIHASLTAKKPKDSSPLSEENVTISPNKDIIKDTDEYLVKIPKVKRYIKFRQSESFPSDRSPVPPNIVKSIKVTETEFKNPLTRESTSEDDVQDNFGQTGVSLDGVPRVKRYIQFTHPEIQSLPQPTITISAEKVGNLGVVQDTRKSSTSSEEDATFIAKEEKAGEQTGLSFEKIPKVKRYIQFVNSESKLVQSATNHSSERLQISGVVQERRSSTSSEEDVKPSTHDDNVRGDYFDKIPKVKRYIKFTQSEPPQGLAPLPISSNVKPTQVTDLQSRGPSTLVDPSPKEDNVFEETEAHLDKLPKVKRYIEFKHQLPVQSTTLSEDKVATSKVILETSRSRTSSEDEVTTESREDYFGQHSEAPLDKIPRVKRYIQFTHPESQIPVQITAKRVSASVVKKETSIPCTSSDDDRKSSTNDHDVIKETSVTIPKVKRYIEFTQCKPFSSPQTQLPSVVKPIKVTATEATVSRTSQSTSDDSDSIPKVKRYIEFTPDESHNSALPSTADLAERLGTSEITEEPKILTTSTKYVKPSATDHIRETDEFIANIPKVKRYIEFKQSYSSPVSSFLPSSNLSSEPSRPISKKKGSAVIIKTELESWMSDQTGLNSESSMSSSLLSKHQVVDEPPAVPITSPPPLDLDAREYLRENTEVRQRQERRRLLQQRRREMDEFNIASLSSMQQEGEKQDRTLADYGGAPFQTERTYSSSSTRNNSRSTEGVEAPVLRGLKTKSTSTLDSKSPANSTTKNKEFLI", "length": 2562, "header": "tr|A0A8M9PHT1-1|A0A8M9PHT1_DANRE Isoform 1 of Leucine-rich repeat-containing protein 66 OS=Danio rerio OX=7955 GN=lrrc66 PE=4 SV=1 CANONICAL=A0A8M9PHT1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PHT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHT1/entry#A0A8M9PHT1-1", "sequence": { "sequence": "MSASRLVFGVAVLLLQLWGTRCFPSSACPIPCLCQPGPVLNCSSLGLNKAPSWIPESAVSLNISNNALSSLAPLSFGHVKLKGLLHLWVGSNGLESLSLILGPGTRTLSSAEQECSSWAPDLQLLSAERNHLKRLPNGLGCIKSLQILQLSYNQISVISLSDLDNCSHLKELHLQHNSITTIHPHAFKDLQQLKVLDLSYNLLVTVPVPAYQSLRNLDALVDVSFNRWKCDCNLQTLRKWMSFDTEMGHASWKVVCASPPHHAGKDLLYLNDSELTCPTYEHRTSGHYHNMIVKEGMQISIPCRNHSQGIMQVRWWTPQGQEKDNQPELLIKDITEQHAGLYICITGVQGEHISVFDLHVYKKGGGSRLRREAGVILDEKGNVILPKNPAVRVGSRTESEFILAVCLSVIITFILAFILGVVLRPLLDKLWRRIRSKRQSTSSPTSSTEPQPYVNEGYCDVEDHDREVRVGSRVTFGEVTEVQDQMPYYVTVDEDQADGSSESNTESGGLYEDVENNRSSVTDEKQQTLEMERHRGRADSSGSSSLQEGEVNALVVNGQKLPPSSMEDMEFEPIPDETEITRIKRRDSSSASSHSSQEVTLSSEIKHSTEQSVDPSPVAKSEIPGFIKEPFSEWPVRLKEQNVDELDPEMWNDSGESFSFNEDSERSSIHDLSSPALGHPLKDDDKWRQIKVASPSNKINIDSDDDFEKPFGKEVLVDGGKQFEFSDNGSSCNSSQSGESVGGPNNYTVNPELEEIVDESDTGNGANVVNLNRFGTLEDPTFRETMPSAGILIRQETIILEPSDIHLTFTHGNSVDEGMLTDDSSMSSLMNIPHQSGQFADIGIDTVPKDKRYVEFKSSKSHSGSPPLSPSSQKNNILSKEHLISEAHTGASFEDNSSLMQRQVSPDNIQKVKRYIGFNPSDPHTQTLPSPSLTKKDALLETKRYSLSSDDDAQLTTKDDKSFLTTSIPSDVSKVKRYISFKQFDTSSPTLPLSKSETTTEATIQNLQPSSSQNVKEHMFFKQHESHSTSLPSSPTSTRKGLSGKKSKSKKRNDQSFYGSHENLPLYHVHPSYRSSINRLNRGYDTDISFSSEDEDQFIEYPRKLEITTAPGLNGGSIKPGKSKDNVLNIDFDNSSSSTDVFEKKRSKGLMRLKALGARLFNRNENETDVMMSPADWDAGRTGGVSVNKQSKLTKKQTTDDDVIFGKSLSFDHLPKVKRYIQFSHSYPQAQLPSPPPTTSTITPDFKVTTESRTSSFSSEDDFKPTTEDETFGGQVDASFDRLPKVKRYIQFSHVEPYSTTLPLKGSPELVVQPESRRSSTSSDDNDIKPNEDSFFSQIGVSFDSVPHVKRYIQFNQPKPYSPTQTSSPISIKRPAVEVETSSSTSVKSDDKSDATGNWGQIDLNAVPKVKRYVQFTEFKDSSTPPLVSSSSTKVTTEMEIKTESTIERFPKDQENLTQAEVSFLENIPKVKRYIHFKQSEPHPTTSDTLHVTPEMIIKSETRRSSTSSEEDIKLTKNEGHVLEETVTSLNSVPRVKRYIQFTYPESQPLTQVSSERVNTSVVEKETRRWSTSSEEDVKPATKENFGETEEYHFQIPKVKRYIKFTEAEPYSSPLSPIPPAITVKETEKEFKPPANRESTSSENHDQEQIGVSLDKVPSVKRYIQFTHPEYQYPSQTSTSLLSESVSIPAVDKETRRWSTSSEEDVKPPTEDIKETDEYLIQIPKVKRYIKFTPSEPHSSAPKQDSPVKSISVTETELKQPVIKENSSTKDVVQEDNVSGQIGVSLDGVPRVKRYIAFTHPETSTAFSDERIHASLTAKKPKDSSPLSEENVTISPNKDIIKDTDEYLVKIPKVKRYIKFRQSESFPSDRSPVPPNIVKSIKVTETEFKNPLTRESTSEDDVQDNFGQTGVSLDGVPRVKRYIQFTHPEIQSLPQPTITISAEKVGNLGVVQDTRKSSTSSEEDATFIAKEEKAGEQTGLSFEKIPKVKRYIQFVNSESKLVQSATNHSSERLQISGVVQERRSSTSSEEDVKPSTHDDNVRGDYFDKIPKVKRYIKFTQSEPPQGLAPLPISSNVKPTQVTDLQSRGPSTLVDPSPKEDNVFEETEAHLDKLPKVKRYIEFKHQLPVQSTTLSEDKVATSKVILETSRSRTSSEDEVTTESREDYFGQHSEAPLDKIPRVKRYIQFTHPESQIPVQITAKRVSASVVKKETSIPCTSSDDDRKSSTNDHDVIKETSVTIPKVKRYIEFTQCKPFSSPQTQLPSVVKPIKVTATEATVSRTSQSTSDDSDSIPKVKRYIEFTPDESHNSALPSTADLAERLGTSEITEEPKILTTSTKYVKPSATDHIRETDEFIANIPKVKRYIEFKQSYSSPVSSFLPSSNLSSEPSRPISKKKGSAVIIKTELESWMSDQTGLNSESSMSSSLLSKHQVVDEPPAVPITSPPPLDLDAREYLRENTEVRQRQERRRLLQQRRREMDEFNIASLSSMQQEGEKQDRTLADYGGAPFQTERTYSSSSTRNNSRSTEGVEAPVLRGLKTKSTSTLDSKSPANSTTKNKEFLI", "length": 2562, "header": "tr|A0A8M9PHT1-1|A0A8M9PHT1_DANRE Isoform 1 of Leucine-rich repeat-containing protein 66 OS=Danio rerio OX=7955 GN=lrrc66 PE=4 SV=1 CANONICAL=A0A8M9PHT1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101882481", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882481", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1134, "end_pos": 1136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1166, "end_pos": 1168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1456, "end_pos": 1458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1559, "end_pos": 1561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1766, "end_pos": 1768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1777, "end_pos": 1779, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1831, "end_pos": 1833, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2007, "end_pos": 2009, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2383, "end_pos": 2385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2521, "end_pos": 2523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2552, "end_pos": 2554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" }, { "start_pos": 733, "end_pos": 735, "annotation": "n_glycosylation_sequon" }, { "start_pos": 746, "end_pos": 748, "annotation": "n_glycosylation_sequon" }, { "start_pos": 896, "end_pos": 898, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PHT1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHT1" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 278, "end_pos": 354, "start_aa": "Pro", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1134, "end_pos": 1136 }, { "start_pos": 1166, "end_pos": 1168 }, { "start_pos": 1456, "end_pos": 1458 }, { "start_pos": 1559, "end_pos": 1561 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 1766, "end_pos": 1768 }, { "start_pos": 1777, "end_pos": 1779 }, { "start_pos": 1831, "end_pos": 1833 }, { "start_pos": 2007, "end_pos": 2009 }, { "start_pos": 2383, "end_pos": 2385 }, { "start_pos": 2521, "end_pos": 2523 }, { "start_pos": 2552, "end_pos": 2554 }, { "start_pos": 271, "end_pos": 273 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 517, "end_pos": 519 }, { "start_pos": 62, "end_pos": 64 }, { "start_pos": 652, "end_pos": 654 }, { "start_pos": 728, "end_pos": 730 }, { "start_pos": 733, "end_pos": 735 }, { "start_pos": 746, "end_pos": 748 }, { "start_pos": 896, "end_pos": 898 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PHY2-1", "uniprot_ac": "A0A8M9PHY2", "uniprot_id": "A0A8M9PHY2_DANRE", "mass": { "chemical_mass": 83220.0, "monoisotopic_mass": 83220.0 }, "refseq": { "ac": "XP_021330972", "name": "cytolytic toxin-alpha-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330972" }, "gene_names": [ { "name": "LOC100004951", "type": "recommended", "evidence": [ { "id": "A0A8M9PHY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHY2" } ] }, { "name": "LOC100004951", "type": "synonym", "evidence": [ { "id": "XP_021330972", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330972" } ] } ], "protein_names": [ { "name": "Cytolytic toxin-alpha-like", "type": "synonym", "evidence": [ { "id": "A0A8M9PHY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHY2/entry#names_and_taxonomy" } ] }, { "name": "cytolytic toxin-alpha-like", "type": "synonym", "evidence": [ { "id": "XP_021330972", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330972" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021330972.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021330972", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330972" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHY2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100004951", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHY2", "locus": {} } ], "crossref": [ { "id": "A0A8M9PHY2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PHY2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100004951", "url": "https://www.ncbi.nlm.nih.gov/gene/100004951", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001229", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001229", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056072", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056072", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100004951", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004951", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PHY2", "url": "https://www.orthodb.org/?gene=A0A8M9PHY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31594", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31594", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31594:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31594:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21109", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21109", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24674", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24674", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021330972", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021330972", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PHY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PHY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHY2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAGPIELAALGRSLFPGMLYDCRKDSFIPGVTLWNKKSINDNLDSHPQPRTDLKVCGSDSLSDKCNLMDISASLKASFFGGLVEVGGSAKYLHDTKTSNQQSRVTMYYSETTRFDQLIISQLQDFTYQQVFKQKTATHVITAVLYGAQAFMVFDRTLSTNENTQEINGELDVMIKKFPSFSIEGKGSVEMTDSDKNKAEKISCTFHGDFHLEQNPTSYMEALDTYQKLPTLLKENPQNAVPIKVWLYPLHLLNDNVAKLEREIRSSLVSNTVEIIEKLNEVNRVSCDLSKNTLTNDFSDIQERLCSFKESVGIYKTVFQKAVARVLPDIRGGVKEEESLADILKIHHDSPFNAEKLNQWLKDANSELNLLSSYLKTLDKIKLEDSDGLNTILLDPDIDVVVCLTITSLSYEDPDLEKQQEFLKSDQFKQLDKVNYLKAVEPVRKWFNNPDAIRQMRQSLTQFKGFSEANKDDKRMRFIVSAISDSSNPVSSIYLYEKGELKDTKFQLPSKPPPPIVKDVQDKTVSLKLQNPWTGETVKYRVEYKESNADSAAEENWLVIDTRDKDFTLNELEPEKSYLIRYRTVSKVGVSEASDTVSTDKSSAKFRPVGGNSGAEFDFIASSGSIFLKEISITFSETSVNSIQVTFSCGNKMNIGNEEGPNKIHYAFDDSKKIVAATLWPNKDQSKLGGLEFEFDKENTISCKCDQLGDEVSVDVKSGTCYGITGRSDGSKIIALGLYFI", "length": 741, "header": "tr|A0A8M9PHY2-1|A0A8M9PHY2_DANRE Isoform 1 of Cytolytic toxin-alpha-like OS=Danio rerio OX=7955 GN=LOC100004951 PE=4 SV=3 CANONICAL=A0A8M9PHY2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PHY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHY2/entry#A0A8M9PHY2-1", "sequence": { "sequence": "MAAGPIELAALGRSLFPGMLYDCRKDSFIPGVTLWNKKSINDNLDSHPQPRTDLKVCGSDSLSDKCNLMDISASLKASFFGGLVEVGGSAKYLHDTKTSNQQSRVTMYYSETTRFDQLIISQLQDFTYQQVFKQKTATHVITAVLYGAQAFMVFDRTLSTNENTQEINGELDVMIKKFPSFSIEGKGSVEMTDSDKNKAEKISCTFHGDFHLEQNPTSYMEALDTYQKLPTLLKENPQNAVPIKVWLYPLHLLNDNVAKLEREIRSSLVSNTVEIIEKLNEVNRVSCDLSKNTLTNDFSDIQERLCSFKESVGIYKTVFQKAVARVLPDIRGGVKEEESLADILKIHHDSPFNAEKLNQWLKDANSELNLLSSYLKTLDKIKLEDSDGLNTILLDPDIDVVVCLTITSLSYEDPDLEKQQEFLKSDQFKQLDKVNYLKAVEPVRKWFNNPDAIRQMRQSLTQFKGFSEANKDDKRMRFIVSAISDSSNPVSSIYLYEKGELKDTKFQLPSKPPPPIVKDVQDKTVSLKLQNPWTGETVKYRVEYKESNADSAAEENWLVIDTRDKDFTLNELEPEKSYLIRYRTVSKVGVSEASDTVSTDKSSAKFRPVGGNSGAEFDFIASSGSIFLKEISITFSETSVNSIQVTFSCGNKMNIGNEEGPNKIHYAFDDSKKIVAATLWPNKDQSKLGGLEFEFDKENTISCKCDQLGDEVSVDVKSGTCYGITGRSDGSKIIALGLYFI", "length": 741, "header": "tr|A0A8M9PHY2-1|A0A8M9PHY2_DANRE Isoform 1 of Cytolytic toxin-alpha-like OS=Danio rerio OX=7955 GN=LOC100004951 PE=4 SV=3 CANONICAL=A0A8M9PHY2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100004951", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004951", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PHY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHY2" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 511, "end_pos": 604, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PHY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHY2" }, { "id": "PS51752", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51752" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Jacalin-type lectin", "eco_id": "ECO_0000259", "start_pos": 603, "end_pos": 741, "start_aa": "Ser", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PHZ1-1", "uniprot_ac": "A0A8M9PHZ1", "uniprot_id": "A0A8M9PHZ1_DANRE", "mass": { "chemical_mass": 14646.0, "monoisotopic_mass": 14646.0 }, "refseq": { "ac": "NP_001427820", "name": "si:cabz01023700.1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427820" }, "gene_names": [ { "name": "si:cabz01023700.1", "type": "recommended", "evidence": [ { "id": "A0A8M9PHZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHZ1" } ] }, { "name": "LOC137489791", "type": "synonym", "evidence": [ { "id": "A0A8M9PHZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHZ1" } ] }, { "name": "si:cabz01023700.1", "type": "synonym", "evidence": [ { "id": "NP_001427820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427820" } ] } ], "protein_names": [ { "name": "Suppressor APC domain-containing protein 1 isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8M9PHZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHZ1/entry#names_and_taxonomy" } ] }, { "name": "si:cabz01023700.1", "type": "synonym", "evidence": [ { "id": "NP_001427820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427820" } ] }, { "name": "suppressor APC domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001427820", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427820" } ] } ], "function": [ { "annotation": "INFERRED REFSEQ: This record is predicted by genome sequence analysis and is not yet supported by experimental evidence. The reference sequence was derived from JBMGRA010000004.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001427820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427820" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHZ1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:cabz01023700.1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHZ1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-161017-150", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-161017-150", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PHZ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PHZ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "101886090", "url": "https://www.ncbi.nlm.nih.gov/gene/101886090", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:137489791", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:137489791", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PHZ1", "url": "https://www.orthodb.org/?gene=A0A8M9PHZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF11414", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11414", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001427820", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001427820", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PHZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PHZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-161017-150", "url": "https://zfin.org/ZDB-GENE-161017-150", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAREDSYTILILPLQSSLHSPDALHSFYWLKRRRDLEREKDVLWAGLEVVEQTQLWYQTRLQLNSQRHLSTENVDRQGRWSCALRSSLQRVNGSLGSLMTDSSIWINPEENGGSDWDIRWSNAMI", "length": 125, "header": "tr|A0A8M9PHZ1-1|A0A8M9PHZ1_DANRE Isoform 1 of Suppressor APC domain-containing protein 1 isoform X2 OS=Danio rerio OX=7955 GN=si:cabz01023700.1 PE=4 SV=1 CANONICAL=A0A8M9PHZ1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PHZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHZ1/entry#A0A8M9PHZ1-1", "sequence": { "sequence": "MAREDSYTILILPLQSSLHSPDALHSFYWLKRRRDLEREKDVLWAGLEVVEQTQLWYQTRLQLNSQRHLSTENVDRQGRWSCALRSSLQRVNGSLGSLMTDSSIWINPEENGGSDWDIRWSNAMI", "length": 125, "header": "tr|A0A8M9PHZ1-1|A0A8M9PHZ1_DANRE Isoform 1 of Suppressor APC domain-containing protein 1 isoform X2 OS=Danio rerio OX=7955 GN=si:cabz01023700.1 PE=4 SV=1 CANONICAL=A0A8M9PHZ1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:137489791", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:137489791", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0KVV2-1", "protein_name": "Suppressor APC domain containing 1", "gene_name": "Sapcd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESPGPGELPLVQAPYTVLLLPLGTSHQDPGAQNFFLWLQMMQALEREQDALWQGLELLEHSQAWFADRLRETQQRQLQLGALDFGEGACGVRLIRPCPYPLEKLIPVQPRARRECQGRELVAAMGKLRGVEPWLTNPQGEWRVPGWFSLFQELSKQQKGVSHRTGEVISQAPPPGAKGPTLV", "length": 183 }, "evidence": [ { "id": "RGD:1359359", "url": "https://alliancegenome.org/gene/RGD:1359359#orthology", "database": "AGR" }, { "id": "MGI:2388100", "url": "https://alliancegenome.org/gene/MGI:2388100#orthology", "database": "AGR" }, { "id": "HGNC:13938", "url": "https://alliancegenome.org/gene/HGNC:13938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-161017-150", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-161017-150#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5SSQ6-1", "protein_name": "Suppressor APC domain-containing protein 1", "gene_name": "SAPCD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSQGSGGVPLVQAPYTVLLLPLGTSRQDPGAQSFFLWLRRMQALEREQDALWQGLELLQHGQAWFEDHLREAQRQQLHLGALGENFLTDLHSEPGRPPLAQIQKVNICLQNLIHEKELSRQQKGVTQPKEEMAQRGCTKGPRGPTRV", "length": 148 }, "evidence": [ { "id": "RGD:1359359", "url": "https://alliancegenome.org/gene/RGD:1359359#orthology", "database": "AGR" }, { "id": "MGI:2388100", "url": "https://alliancegenome.org/gene/MGI:2388100#orthology", "database": "AGR" }, { "id": "HGNC:13938", "url": "https://alliancegenome.org/gene/HGNC:13938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-161017-150", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-161017-150#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CY86-1", "protein_name": "Suppressor APC domain-containing protein 1", "gene_name": "Sapcd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESPGPGGPPLVQAPYTVLLLPLGTSRQDPGAQNFFLWLQMMQALEREQDALWQGLELLEHGQAWFADRLRETQQRQLQLGALGEDFLMDLHSETDAPLLTRIQKVNACLHSLIHKELSKHRKGVTQSTGEVVSQAPPGPKGPTLV", "length": 146 }, "evidence": [ { "id": "RGD:1359359", "url": "https://alliancegenome.org/gene/RGD:1359359#orthology", "database": "AGR" }, { "id": "MGI:2388100", "url": "https://alliancegenome.org/gene/MGI:2388100#orthology", "database": "AGR" }, { "id": "HGNC:13938", "url": "https://alliancegenome.org/gene/HGNC:13938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-161017-150", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-161017-150#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], 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GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021331111", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331111", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PI83", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PI83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI83-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MANVKQLLDNSLNGLLEAELKKFQWCLVNHHRDISKAEMENADRLKTVDKLVSCFGPERAVKITVDTLRKIKQNELAEELENIQKQGAALENCKSPPVDYTNTSHELKKNLKEEYKQILIGNSQIDRKKYLDDIYTDLYVVENETGGRENDHEVIQIESKHNQQTAKDKPLKCNDMFKVQPGTEQNKRVLTLGIAGVGKTISVSKFILDWVEGKDNQEIVFIFPLPFRSLNLIKEEKYSLIGLLNKYFFSSGGLWSLPEEQGKVMFIFDGLDEYRFELNFKENDGFTDVHKEMTVSKIVTHLLKRQLLRSSLIWITSRPAAASLIPQNYIDQVTEVRGFNDEQKEQYFIKNSSPEVAGNIISHIKKSRSLYIMCHIPVFCWISLTVLQRLLGQESNEKTPTTLTEMYTNFLLSQKQQMKEKYSNDSEPEANAWSFIDIVLKLGKLAFKQLLEGKLIFYKTDLQKCGLDVKEGSLFSGLCTRMFQEENPVSGEQVYSFVHLSVQEFIAALYVFFTYNDKKENLFLDSWKKELTWKLSTKTLFKLHKDAVEKTLQSKNGHLDLFLRFLLGLSLESNQSDLKELLPGMELKTENIKDTTDYIKKKIEKEKSAERAINLFHCLNELKDDFVEELQKSLSSGNLTTQNMSSAQWSGLMFVLLMSEETQEKFELQKYRSSEEALMRLMPVVKNTRRAHLQCCNLTAQSCKSLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKDPNCKLETLRFFMCKLTVNSCKSLSSALQSSNCVLRELDLGDNDLQDSGVKLLSDGLKSPNCKLEILRFVMCKLTVDSCESLSSALQSSNCVLRELDLSDNDLQDSGVKLLFDELKSPNCKLETLRFVMCKLTVDSCESLSLALQSPNCVLRELDLSDNDLQDSGVKLLSDGLNSPNCNLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGDSGVKLLSEKLEDPNYTLDKLNLDHGGETRITAGLRKYVCFVTLDPNAAHTHLVLSEENREVKGVLEEQSYPDHPDRFDHQPQVVCRESVCGRCYWEIDWSGDDVVSISVSYKSINSKGKGDESRFGYNAQSWSLICDASSFKFRHNRTCTRLSVEPLSRKIGVFVDHSAGTLIFYNINGDTMSLIHLVQTTFTEPLYPGFGVYLGSSVKLC", "length": 1172, "header": "tr|A0A8M9PI83-1|A0A8M9PI83_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 OS=Danio rerio OX=7955 GN=LOC110439426 PE=4 SV=3 CANONICAL=A0A8M9PI83-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PI83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI83/entry#A0A8M9PI83-1", "sequence": { "sequence": "MANVKQLLDNSLNGLLEAELKKFQWCLVNHHRDISKAEMENADRLKTVDKLVSCFGPERAVKITVDTLRKIKQNELAEELENIQKQGAALENCKSPPVDYTNTSHELKKNLKEEYKQILIGNSQIDRKKYLDDIYTDLYVVENETGGRENDHEVIQIESKHNQQTAKDKPLKCNDMFKVQPGTEQNKRVLTLGIAGVGKTISVSKFILDWVEGKDNQEIVFIFPLPFRSLNLIKEEKYSLIGLLNKYFFSSGGLWSLPEEQGKVMFIFDGLDEYRFELNFKENDGFTDVHKEMTVSKIVTHLLKRQLLRSSLIWITSRPAAASLIPQNYIDQVTEVRGFNDEQKEQYFIKNSSPEVAGNIISHIKKSRSLYIMCHIPVFCWISLTVLQRLLGQESNEKTPTTLTEMYTNFLLSQKQQMKEKYSNDSEPEANAWSFIDIVLKLGKLAFKQLLEGKLIFYKTDLQKCGLDVKEGSLFSGLCTRMFQEENPVSGEQVYSFVHLSVQEFIAALYVFFTYNDKKENLFLDSWKKELTWKLSTKTLFKLHKDAVEKTLQSKNGHLDLFLRFLLGLSLESNQSDLKELLPGMELKTENIKDTTDYIKKKIEKEKSAERAINLFHCLNELKDDFVEELQKSLSSGNLTTQNMSSAQWSGLMFVLLMSEETQEKFELQKYRSSEEALMRLMPVVKNTRRAHLQCCNLTAQSCKSLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKDPNCKLETLRFFMCKLTVNSCKSLSSALQSSNCVLRELDLGDNDLQDSGVKLLSDGLKSPNCKLEILRFVMCKLTVDSCESLSSALQSSNCVLRELDLSDNDLQDSGVKLLFDELKSPNCKLETLRFVMCKLTVDSCESLSLALQSPNCVLRELDLSDNDLQDSGVKLLSDGLNSPNCNLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGDSGVKLLSEKLEDPNYTLDKLNLDHGGETRITAGLRKYVCFVTLDPNAAHTHLVLSEENREVKGVLEEQSYPDHPDRFDHQPQVVCRESVCGRCYWEIDWSGDDVVSISVSYKSINSKGKGDESRFGYNAQSWSLICDASSFKFRHNRTCTRLSVEPLSRKIGVFVDHSAGTLIFYNINGDTMSLIHLVQTTFTEPLYPGFGVYLGSSVKLC", "length": 1172, "header": "tr|A0A8M9PI83-1|A0A8M9PI83_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 OS=Danio rerio OX=7955 GN=LOC110439426 PE=4 SV=3 CANONICAL=A0A8M9PI83-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "A0A8M9PI83", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M9PI83" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0A8M9PI83", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M9PI83" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:110439426", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110439426", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PI83", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI83" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PI83", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI83" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1107, "end_pos": 1109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 574, "end_pos": 576, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 697, "end_pos": 699, "annotation": "n_glycosylation_sequon" }, { "start_pos": 975, "end_pos": 977, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PI83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI83" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 981, "end_pos": 1172, "start_aa": "Leu", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PI83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI83" }, { "id": "PS50824", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50824" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pyrin", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 86, "start_aa": "Met", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 1107, "end_pos": 1109 }, { "start_pos": 143, "end_pos": 145 }, { "start_pos": 351, "end_pos": 353 }, { "start_pos": 424, "end_pos": 426 }, { "start_pos": 574, "end_pos": 576 }, { "start_pos": 638, "end_pos": 640 }, { "start_pos": 643, "end_pos": 645 }, { "start_pos": 697, "end_pos": 699 }, { "start_pos": 975, "end_pos": 977 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PI92-1", "uniprot_ac": "A0A8M9PI92", "uniprot_id": "A0A8M9PI92_DANRE", "mass": { "chemical_mass": 38466.0, "monoisotopic_mass": 38466.0 }, "refseq": { "ac": "XP_021331122", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331122" }, "gene_names": [ { "name": "LOC103910472", "type": "recommended", "evidence": [ { "id": "A0A8M9PI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI92" } ] }, { "name": "LOC103910472", "type": "synonym", "evidence": [ { "id": "XP_021331122", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331122" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PI92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI92/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021331122", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331122" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021331122.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021331122", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331122" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PI92", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI92#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PI92", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI92" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC103910472", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI92", "locus": {} } ], "crossref": [ { "id": "A0A8M9PI92", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PI92", "database": "AlphaFoldDB", "categories": [] }, { "id": "103910472", "url": "https://www.ncbi.nlm.nih.gov/gene/103910472", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:103910472", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910472", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PI92", "url": "https://www.orthodb.org/?gene=A0A8M9PI92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { 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"MSDPEPCKIKNEDSEQQIDLIEENEGSKEEEHHVKIEEKTHSQTEGILKSRDENRFTCTQCGKSFGRKGYLKIHMRIHTGEKPFTCIQCGKSFIRLSSLNIHMRIHTGEKPFTCTRCGKSFSHSSSLNHHMIIHAGEKPSTCSQCGKSFSCSSHLNHHMRIHTGEKPFTCTQCGKGFSQSSPLNKHMRIHTGEKPFSCTQCGNSFRHSLSLKQHMRIHTGEKPFTCTQCGKSFGQSSSLNHHMRIHTGEKPFTCTQCEKSFSQSSHFNRHMRIHTGEKPFTCARCGKSFSQSSNLNLHMRIHTGEKPFTCTQCGKSFSQSSNCNLHMRIHTGEKPFTCT", "length": 339, "header": "tr|A0A8M9PI92-1|A0A8M9PI92_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC103910472 PE=4 SV=3 CANONICAL=A0A8M9PI92-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PI92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI92/entry#A0A8M9PI92-1", "sequence": { "sequence": 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CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021324609.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324609" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PII1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PII1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "arsb", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PII1", "locus": {} } ], "crossref": [ { "id": "A0A8M9PII1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PII1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16029", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16029", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100538007", "url": 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}, { "id": "PTHR10342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10342:SF274", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10342:SF274", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00884", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021324609", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324609", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PII1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PII1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PII1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PII1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSVGNLGLCLLCVVLECVSARPPHVVLILADDLGWNDVGFHGSEIKTPHLDRLAAQGVRLDNYYVQPLCTPSRNQLMTGRYQIRTGLQHQIIWPCQPYCVPLDEKLLPQVLRERGYHTHMVGKWHLGMFQKDCLPTHRGFQSFFGYLTGSEDYYTHKRCSLIAPLNVTRCALDLRDGDAVALNYSGRYSTELLTERATHIITQHTPDQPLFLYVALQAVHAPLQVPDRYIAPYSFIQDPHRRRYAGMVSAMDEAVGNITHTLQETGLWDNTVLIFSTDNGGQTLYGGNNWPLRGRKWTLWEGGVRGVAFVSGPLIEKPGAVNRELIHISDWLPTIAGLAGASTNGTKPLDGFDVWQSISAGVASPRVELLHNIDPLYEDSSPCPGGEGVFLEDSLHSSSSSSSSSSSDVSAQFNISIHAAIRHKNWKLLTGYPGCPLWIPPPGGRPVNASEPLKQVMLFDVEKDPEERLEVSHQRPEVVSFLLRRLQLYQNQAQPIHFPPDDPRCDPATTGAWGPWE", "length": 517, "header": "tr|A0A8M9PII1-1|A0A8M9PII1_DANRE Isoform 1 of Arylsulfatase B OS=Danio rerio OX=7955 GN=arsb PE=3 SV=2 CANONICAL=A0A8M9PII1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PII1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PII1/entry#A0A8M9PII1-1", "sequence": { "sequence": "MSVGNLGLCLLCVVLECVSARPPHVVLILADDLGWNDVGFHGSEIKTPHLDRLAAQGVRLDNYYVQPLCTPSRNQLMTGRYQIRTGLQHQIIWPCQPYCVPLDEKLLPQVLRERGYHTHMVGKWHLGMFQKDCLPTHRGFQSFFGYLTGSEDYYTHKRCSLIAPLNVTRCALDLRDGDAVALNYSGRYSTELLTERATHIITQHTPDQPLFLYVALQAVHAPLQVPDRYIAPYSFIQDPHRRRYAGMVSAMDEAVGNITHTLQETGLWDNTVLIFSTDNGGQTLYGGNNWPLRGRKWTLWEGGVRGVAFVSGPLIEKPGAVNRELIHISDWLPTIAGLAGASTNGTKPLDGFDVWQSISAGVASPRVELLHNIDPLYEDSSPCPGGEGVFLEDSLHSSSSSSSSSSSDVSAQFNISIHAAIRHKNWKLLTGYPGCPLWIPPPGGRPVNASEPLKQVMLFDVEKDPEERLEVSHQRPEVVSFLLRRLQLYQNQAQPIHFPPDDPRCDPATTGAWGPWE", "length": 517, "header": "tr|A0A8M9PII1-1|A0A8M9PII1_DANRE Isoform 1 of Arylsulfatase B OS=Danio rerio OX=7955 GN=arsb PE=3 SV=2 CANONICAL=A0A8M9PII1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "A0A8M9PII1", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M9PII1" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0A8M9PII1", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8M9PII1" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:100538007", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100538007", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PII1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PII1" } ], "pmid": "" }, { "name": "sulfuric ester hydrolase activity", "id": "GO:0008484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008484", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PII1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PII1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 344, "end_pos": 346, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PII1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PII1" }, { "id": "PF00884", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00884" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sulfatase N-terminal", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 341, "start_aa": "Pro", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 344, "end_pos": 346 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 448, "end_pos": 450 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PIJ4-1", "uniprot_ac": "A0A8M9PIJ4", "uniprot_id": "A0A8M9PIJ4_DANRE", "mass": { "chemical_mass": 49730.0, "monoisotopic_mass": 49730.0 }, "refseq": { "ac": "XP_017208521", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208521" }, "gene_names": [ { "name": "LOC108180795", "type": "recommended", "evidence": [ { "id": "A0A8M9PIJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIJ4" } ] }, { "name": "LOC108180795", "type": "synonym", "evidence": [ { "id": "XP_017208521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208521" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PIJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIJ4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_017208521", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208521" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017208521", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208521" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIJ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108180795", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIJ4", "locus": {} } ], "crossref": [ { "id": "108180795", "url": "https://www.ncbi.nlm.nih.gov/gene/108180795", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108180795", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108180795", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PIJ4", "url": "https://www.orthodb.org/?gene=A0A8M9PIJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017208521", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208521", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PIJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEIEEEPCRIKEEETEEQIDQAEGNEDKQHLFNNPQRFTSEHSQMKTEQKYIQIEQDRRIRVIGSFICCECGKSLKSELWLKKHTMMVHTGEKLLTCTQCGKGFVDEAKLESHLKSHTRNRSFTCTECGKMLKSEDKLNNHVRIHNKERPFSCSVCGKSFKTEHNLSQHQRVYCDVKPLSCDQCHKTFLSRSRLKSHLKFHSEVKPHVCSLCGKSFLYLNMLKEHELIHSGVKPHVCSDCGKSFSSSNYLKKHQIVHTDVNPFSCTQCGKTFKEKRSLKDHLTAHAGVKPFSCDQCDKTFLSASYLRKHLKVHSGLKPHVCSFCGKSFLALQALKLHQMIHTGERPYVCSECGDSFLRSNYLKKHQRIHTGEKPFACAQCGKSFRYKNNLKVHLVSHTGVKPFSCDQCHKTFVCSTNLRNHLKMHASVKPQT", "length": 432, "header": "tr|A0A8M9PIJ4-1|A0A8M9PIJ4_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC108180795 PE=3 SV=1 CANONICAL=A0A8M9PIJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PIJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIJ4/entry#A0A8M9PIJ4-1", "sequence": { "sequence": "MEIEEEPCRIKEEETEEQIDQAEGNEDKQHLFNNPQRFTSEHSQMKTEQKYIQIEQDRRIRVIGSFICCECGKSLKSELWLKKHTMMVHTGEKLLTCTQCGKGFVDEAKLESHLKSHTRNRSFTCTECGKMLKSEDKLNNHVRIHNKERPFSCSVCGKSFKTEHNLSQHQRVYCDVKPLSCDQCHKTFLSRSRLKSHLKFHSEVKPHVCSLCGKSFLYLNMLKEHELIHSGVKPHVCSDCGKSFSSSNYLKKHQIVHTDVNPFSCTQCGKTFKEKRSLKDHLTAHAGVKPFSCDQCDKTFLSASYLRKHLKVHSGLKPHVCSFCGKSFLALQALKLHQMIHTGERPYVCSECGDSFLRSNYLKKHQRIHTGEKPFACAQCGKSFRYKNNLKVHLVSHTGVKPFSCDQCHKTFVCSTNLRNHLKMHASVKPQT", "length": 432, "header": "tr|A0A8M9PIJ4-1|A0A8M9PIJ4_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC108180795 PE=3 SV=1 CANONICAL=A0A8M9PIJ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108180795", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108180795", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": 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"A0A8M9PIM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIM7" } ] }, { "name": "LOC101886407", "type": "synonym", "evidence": [ { "id": "XP_021331292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331292" } ] } ], "protein_names": [ { "name": "Sterile alpha motif domain-containing protein 3-like", "type": "synonym", "evidence": [ { "id": "A0A8M9PIM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIM7/entry#names_and_taxonomy" } ] }, { "name": "sterile alpha motif domain-containing protein 3-like", "type": "synonym", "evidence": [ { "id": "XP_021331292", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331292" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation 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This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. 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"type": "synonym", "evidence": [ { "id": "XP_021326813", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326813" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021326813.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326813", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326813" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIN9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIN9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101882365", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIN9", "locus": {} } ], "crossref": [ { "id": "A0A8M9PIN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PIN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "101882365", "url": "https://www.ncbi.nlm.nih.gov/gene/101882365", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", 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COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021331312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331312" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIP6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0AC58JEB3", "url": "https://www.uniprot.org/uniprotkb/A0AC58JEB3#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIP6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108183829", "url": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24394:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24394:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021331312", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331312", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PIP6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JEB3", "url": "https://www.uniprot.org/uniprotkb/A0AC58JEB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JEB3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JEB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVAKKKKLNKMTFILAGCCDVIRRRRFCALFQQEKGSVRTQRKTPAEATDLHTVIKMAFVKEESEDVKIEETFTVKQEDLQEQTDLVKEYERSKEEEHHVKIEDKTHLETDDILKMRDKRCFTCNQCGKSLANRNKLKIHMRIHNREKLFTCTQCGKNFDQSSNLNQHMRIHTGEKPFTCTHCGKSFSNSANLNQHMRIHTGEKPFTCTQCGKSFSQSSYLNQHMRIHTGEKPFTCSQCGKSFSQSSSLNLHMRIHTGEKPFTCTQCGKSFSQSSNLNIHMRNHTGEKPFTCLQCGKSFSRSTSLNQHMMMHTGEKEYMCLKCEKTFITAAKLKRHQRVHTGEKPYKCSQCSKRFARSGTLKTHERIHTGEKL", "length": 374, "header": "tr|A0A8M9PIP6-1|A0A8M9PIP6_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC108183829 PE=3 SV=2 CANONICAL=A0A8M9PIP6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PIP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6/entry#A0A8M9PIP6-1", "sequence": { "sequence": "MTVAKKKKLNKMTFILAGCCDVIRRRRFCALFQQEKGSVRTQRKTPAEATDLHTVIKMAFVKEESEDVKIEETFTVKQEDLQEQTDLVKEYERSKEEEHHVKIEDKTHLETDDILKMRDKRCFTCNQCGKSLANRNKLKIHMRIHNREKLFTCTQCGKNFDQSSNLNQHMRIHTGEKPFTCTHCGKSFSNSANLNQHMRIHTGEKPFTCTQCGKSFSQSSYLNQHMRIHTGEKPFTCSQCGKSFSQSSSLNLHMRIHTGEKPFTCTQCGKSFSQSSNLNIHMRNHTGEKPFTCLQCGKSFSRSTSLNQHMMMHTGEKEYMCLKCEKTFITAAKLKRHQRVHTGEKPYKCSQCSKRFARSGTLKTHERIHTGEKL", "length": 374, "header": "tr|A0A8M9PIP6-1|A0A8M9PIP6_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC108183829 PE=3 SV=2 CANONICAL=A0A8M9PIP6-1" }, "locus": {} }, { "isoform_ac": "A0AC58JEB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6/entry#A0AC58JEB3-1", "sequence": { "sequence": "MAFVKEESEDVKIEETFTVKQEDLQEQTDLVKEYERSKEEEHHVKIEDKTHLETDDILKMRDKRCFTCNQCGKSLANRNKLKIHMRIHNREKLFTCTQCGKNFDQSSNLNQHMRIHTGEKPFTCTHCGKSFSNSANLNQHMRIHTGEKPFTCTQCGKSFSQSSYLNQHMRIHTGEKPFTCSQCGKSFSQSSSLNLHMRIHTGEKPFTCTQCGKSFSQSSNLNIHMRNHTGEKPFTCLQCGKSFSRSTSLNQHMMMHTGEKEYMCLKCEKTFITAAKLKRHQRVHTGEKPYKCSQCSKRFARSGTLKTHERIHTGEKL", "length": 317, "header": "tr|A0AC58JEB3-1|A0AC58JEB3_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC108183829 PE=3 SV=1 CANONICAL=A0A8M9PIP6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108183829", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108183829", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIP6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIP6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIP6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIP6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIP6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIP6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PIP6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIP6" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 123, "end_pos": 150, "start_aa": "Phe", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 284, "end_pos": 286 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PIR4-1", "uniprot_ac": "A0A8M9PIR4", "uniprot_id": "A0A8M9PIR4_DANRE", "mass": { "chemical_mass": 96136.0, "monoisotopic_mass": 96136.0 }, "refseq": { "ac": "NP_001429409", "name": "ecotropic viral integration site 2B precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429409" }, "gene_names": [ { "name": "evi2b", "type": "recommended", "evidence": [ { "id": "A0A8M9PIR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIR4" } ] }, { "name": "evi2b", "type": "synonym", "evidence": [ { "id": "NP_001429409", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429409" } ] } ], "protein_names": [ { "name": "Protein EVI2B", "type": "synonym", "evidence": [ { "id": "A0A8M9PIR4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIR4/entry#names_and_taxonomy" } ] }, { "name": "ecotropic viral integration site 2B precursor", "type": "synonym", "evidence": [ { "id": "NP_001429409", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429409" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01022639.1, GDQH01020443.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476771, SAMEA4476772 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Aug 8, 2025 this sequence version replaced XP_021322126.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001429409", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429409" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIR4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "evi2b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIR4", "locus": {} } ], "crossref": [ { "id": "A0A8M9PIR4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PIR4", "database": "AlphaFoldDB", "categories": [] }, { "id": "101882500", "url": "https://www.ncbi.nlm.nih.gov/gene/101882500", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR060671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101882500", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882500", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PIR4", "url": "https://www.orthodb.org/?gene=A0A8M9PIR4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF27913", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27913", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001429409", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429409", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PIR4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIR4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPRFSKDTMRATLCTIAFLYFLPWSLNGHLTTSHKNTVVPNTADKASGQREYTIDSGIDNVVSVSKSIQMLHLRSHSEQQGIRSKTPYADDKLSNQRTSKNAENDQYNLTTLLAQPKTKLSQEVASTPQKEQRKMTESWYREKSTSPLQKVLTHHALTKRPNTTNANVSPKEPRSMGPLDTLEATQISVSRSVQTKDFTSHSDQQGVHSRFTLKGEEETSYRSRKTHDDQGLTTMLAQPNNKILQNVKTTVQKEDKQTNSSHRPHTTFPLQIENTTELFASTKTPNTTRTDVLPEKAKYVLVSRSKQMQKLTSHSGQRIVHPRTLNGETPNRRTKRNEGDGEYTFGPTENHLTQRAATTAQKEQANMSETSNIPDSTFLTRTENAAESIKIPYITKVDTLRTSMGPSETREVIQVSQSRSVQTQDFTSHSKQPDLLQTFRNEDETSNWRTKRNADDSQQNLTPTLTQPIKLITQEVTTTPNKKRKPTEIHHRLHNSSLQIENATEFNISTQPPIATTTNFSQIGTTKRDHSETQETTLETLSTTDFSGLYGVEKNETDANKNNTYKDVHTSHTTMGTSKEPSPMTHAHTSAIIAETNVSGAATVGLKTTEGKVTIKWTQGPEVKTQPVTKTKKSSTTKKTTPKQSTTLSIKKDSQKANPGPAVAGVIVTTFLLMFIAIIIILVRKRKMQKRQLENPVWAGPSPFLDGDVHPNLPTMDESEAINRHSFNQMSISNHLAFGRNTSEDVFMEDIPQGSTFGVQNPDETNATNGNSTAVQDPIQAEENKIQDGQAPVDSSSDTKTPSAETAQGPVIDNGESEQADDLTPSSFKDIAIKPPPLVSIDLDSLSEEAAPFQTSDSVDAPAPPQP", "length": 867, "header": "tr|A0A8M9PIR4-1|A0A8M9PIR4_DANRE Isoform 1 of Protein EVI2B OS=Danio rerio OX=7955 GN=evi2b PE=4 SV=1 CANONICAL=A0A8M9PIR4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PIR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIR4/entry#A0A8M9PIR4-1", "sequence": { "sequence": "MPRFSKDTMRATLCTIAFLYFLPWSLNGHLTTSHKNTVVPNTADKASGQREYTIDSGIDNVVSVSKSIQMLHLRSHSEQQGIRSKTPYADDKLSNQRTSKNAENDQYNLTTLLAQPKTKLSQEVASTPQKEQRKMTESWYREKSTSPLQKVLTHHALTKRPNTTNANVSPKEPRSMGPLDTLEATQISVSRSVQTKDFTSHSDQQGVHSRFTLKGEEETSYRSRKTHDDQGLTTMLAQPNNKILQNVKTTVQKEDKQTNSSHRPHTTFPLQIENTTELFASTKTPNTTRTDVLPEKAKYVLVSRSKQMQKLTSHSGQRIVHPRTLNGETPNRRTKRNEGDGEYTFGPTENHLTQRAATTAQKEQANMSETSNIPDSTFLTRTENAAESIKIPYITKVDTLRTSMGPSETREVIQVSQSRSVQTQDFTSHSKQPDLLQTFRNEDETSNWRTKRNADDSQQNLTPTLTQPIKLITQEVTTTPNKKRKPTEIHHRLHNSSLQIENATEFNISTQPPIATTTNFSQIGTTKRDHSETQETTLETLSTTDFSGLYGVEKNETDANKNNTYKDVHTSHTTMGTSKEPSPMTHAHTSAIIAETNVSGAATVGLKTTEGKVTIKWTQGPEVKTQPVTKTKKSSTTKKTTPKQSTTLSIKKDSQKANPGPAVAGVIVTTFLLMFIAIIIILVRKRKMQKRQLENPVWAGPSPFLDGDVHPNLPTMDESEAINRHSFNQMSISNHLAFGRNTSEDVFMEDIPQGSTFGVQNPDETNATNGNSTAVQDPIQAEENKIQDGQAPVDSSSDTKTPSAETAQGPVIDNGESEQADDLTPSSFKDIAIKPPPLVSIDLDSLSEEAAPFQTSDSVDAPAPPQP", "length": 867, "header": "tr|A0A8M9PIR4-1|A0A8M9PIR4_DANRE Isoform 1 of Protein EVI2B OS=Danio rerio OX=7955 GN=evi2b PE=4 SV=1 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"MGPLLLKLLLQGVLLFDALAWNVNMPQAIHGLQGSCLVIPCSFSYTLYPPKDPRRVVWYQWVSRGYPLVYDSWYPRDVIDKFRGKTDLYRNSGWDCSLLIKNLEQSHHREKIYAWIDPENVGWRTYAFYDITSTILVENQPPTPTILIYGGEKMGDKITVVCSSFHTCPWSKPNITLNGAKGSESDQIKDECNEYGHCKINLTRTVVVKAENTAFNCSVTYHGGKSISAAIDKSAQCVHHRIVIEPEMADVTEGVAQNFTCTIYHSCQKENPSISWNYENMQVSEGRKTLSGSDRVAFSNITFLGTIEDQGRKLTCTASFSGGNIAASAVLRVQKYQKPAIPVQNETYFQYMADVIPEITALPRSCVVIPCSFSVEHKYLTGLRVRWVNNNGGYMYHTDPVDVLDNFKGRTRLLGNPDERNCTLEMDDVRTHDNGPFCFQAEKKEEKYSFNNSCVFIIMRASPDQPVMSSVPEDIEPGTAVTVKCSVKHTCSSHPPKITWSVPTVRETISHNPMGGGVWETVSKMKFIPTGYEEEDEIICSANFWGGKTQSNSSAPLSVKRIQAVESGPYIIASSLVFVLICILAGVFMYKRHQRQPCEDITRSEQRRSVWNRFSSRFSMPEGRAAWFNSGNRSDIRDAPGRPPKPEQRRSIWSRFSRHQSPRNNANMRAEYKANNTCNVPENKDFNKPHMPSPNSQRKNCGGYDYDADYNLYGNV", "length": 716, "header": "tr|A0A8M9PIT8-1|A0A8M9PIT8_DANRE Isoform 1 of Ig-like domain-containing protein OS=Danio rerio OX=7955 GN=LOC101884840 PE=4 SV=2 CANONICAL=A0A8M9PIT8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PIT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIT8/entry#A0A8M9PIT8-1", "sequence": { "sequence": "MGPLLLKLLLQGVLLFDALAWNVNMPQAIHGLQGSCLVIPCSFSYTLYPPKDPRRVVWYQWVSRGYPLVYDSWYPRDVIDKFRGKTDLYRNSGWDCSLLIKNLEQSHHREKIYAWIDPENVGWRTYAFYDITSTILVENQPPTPTILIYGGEKMGDKITVVCSSFHTCPWSKPNITLNGAKGSESDQIKDECNEYGHCKINLTRTVVVKAENTAFNCSVTYHGGKSISAAIDKSAQCVHHRIVIEPEMADVTEGVAQNFTCTIYHSCQKENPSISWNYENMQVSEGRKTLSGSDRVAFSNITFLGTIEDQGRKLTCTASFSGGNIAASAVLRVQKYQKPAIPVQNETYFQYMADVIPEITALPRSCVVIPCSFSVEHKYLTGLRVRWVNNNGGYMYHTDPVDVLDNFKGRTRLLGNPDERNCTLEMDDVRTHDNGPFCFQAEKKEEKYSFNNSCVFIIMRASPDQPVMSSVPEDIEPGTAVTVKCSVKHTCSSHPPKITWSVPTVRETISHNPMGGGVWETVSKMKFIPTGYEEEDEIICSANFWGGKTQSNSSAPLSVKRIQAVESGPYIIASSLVFVLICILAGVFMYKRHQRQPCEDITRSEQRRSVWNRFSSRFSMPEGRAAWFNSGNRSDIRDAPGRPPKPEQRRSIWSRFSRHQSPRNNANMRAEYKANNTCNVPENKDFNKPHMPSPNSQRKNCGGYDYDADYNLYGNV", "length": 716, "header": "tr|A0A8M9PIT8-1|A0A8M9PIT8_DANRE Isoform 1 of Ig-like domain-containing protein OS=Danio rerio OX=7955 GN=LOC101884840 PE=4 SV=2 CANONICAL=A0A8M9PIT8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101884840", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884840", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 300, "end_pos": 302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 345, "end_pos": 347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 675, "end_pos": 677, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PIT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIT8" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 240, "end_pos": 332, "start_aa": "His", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 174, "end_pos": 176 }, { "start_pos": 201, "end_pos": 203 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 258, "end_pos": 260 }, { "start_pos": 300, "end_pos": 302 }, { "start_pos": 345, "end_pos": 347 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 632, "end_pos": 634 }, { "start_pos": 675, "end_pos": 677 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PIV5-1", "uniprot_ac": "A0A8M9PIV5", "uniprot_id": "A0A8M9PIV5_DANRE", "mass": { "chemical_mass": 36756.0, "monoisotopic_mass": 36756.0 }, "refseq": { "ac": "XP_021331372", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331372" }, "gene_names": [ { "name": "LOC103910801", "type": "recommended", "evidence": [ { "id": "A0A8M9PIV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5" } ] }, { "name": "LOC103910801", "type": "synonym", "evidence": [ { "id": "XP_021331372", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331372" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PIV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021331372", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331372" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021331372.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021331372", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331372" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0AC58JEP0", "url": "https://www.uniprot.org/uniprotkb/A0AC58JEP0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC103910801", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5", "locus": {} } ], "crossref": [ { "id": "A0A8M9PIV5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PIV5", "database": "AlphaFoldDB", "categories": [] }, { "id": "103910801", "url": "https://www.ncbi.nlm.nih.gov/gene/103910801", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051497", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051497", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:103910801", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910801", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PIV5", "url": "https://www.orthodb.org/?gene=A0A8M9PIV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF178", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF178", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45993", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45993", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45993:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45993:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021331372", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331372", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PIV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JEP0", "url": "https://www.uniprot.org/uniprotkb/A0AC58JEP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JEP0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JEP0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKHEDLQEQTDLIEENEESKEEEHHVKIEEKTQLQTDGVLKRRDKNRFTCTQCGKSLANKSKLKIHMRIHTGEKPFTCTQCGKSFNISSHLNHHMRIHTGEKPFTCAQCGKSFNQSSHLNYHMMIHTGKKPFTCTQCAKSFNQSSHLNLHMMIHTGEKPFTCTHCGKSFNCSSHLIQHTRIHTGEKPFTCTQCGKSFSHSSHLNLHMRIHTGEKPFTCTQCGKSFSQSSHLNLHMRIHTGEKPFSCTICGKSFNCSSHRNQHMRSHTGEKPYTCTQCGKSFSKSSSLNKHVERTHGHIAVVNTS", "length": 322, "header": "tr|A0A8M9PIV5-1|A0A8M9PIV5_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC103910801 PE=4 SV=2 CANONICAL=A0A8M9PIV5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PIV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5/entry#A0A8M9PIV5-1", "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKHEDLQEQTDLIEENEESKEEEHHVKIEEKTQLQTDGVLKRRDKNRFTCTQCGKSLANKSKLKIHMRIHTGEKPFTCTQCGKSFNISSHLNHHMRIHTGEKPFTCAQCGKSFNQSSHLNYHMMIHTGKKPFTCTQCAKSFNQSSHLNLHMMIHTGEKPFTCTHCGKSFNCSSHLIQHTRIHTGEKPFTCTQCGKSFSHSSHLNLHMRIHTGEKPFTCTQCGKSFSQSSHLNLHMRIHTGEKPFSCTICGKSFNCSSHRNQHMRSHTGEKPYTCTQCGKSFSKSSSLNKHVERTHGHIAVVNTS", "length": 322, "header": "tr|A0A8M9PIV5-1|A0A8M9PIV5_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC103910801 PE=4 SV=2 CANONICAL=A0A8M9PIV5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JEP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5/entry#A0AC58JEP0-1", "sequence": { "sequence": "MRIHTGEKPFTCTQCGKSFNISSHLNHHMRIHTGEKPFTCAQCGKSFNQSSHLNYHMMIHTGKKPFTCTQCAKSFNQSSHLNLHMMIHTGEKPFTCTHCGKSFNCSSHLIQHTRIHTGEKPFTCTQCGKSFSHSSHLNLHMRIHTGEKPFTCTQCGKSFSQSSHLNLHMRIHTGEKPFSCTICGKSFNCSSHRNQHMRSHTGEKPYTCTQCGKSFSKSSSLNKHVERTHGHIAVVNTS", "length": 238, "header": "tr|A0AC58JEP0-1|A0AC58JEP0_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC103910801 PE=4 SV=1 CANONICAL=A0A8M9PIV5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103910801", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910801", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 320, "end_pos": 322, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PIV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIV5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 93, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 132, "end_pos": 134 }, { "start_pos": 160, "end_pos": 162 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 320, "end_pos": 322 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PIY0-1", "uniprot_ac": "A0A8M9PIY0", "uniprot_id": "A0A8M9PIY0_DANRE", "mass": { "chemical_mass": 172900.0, "monoisotopic_mass": 172900.0 }, "refseq": { "ac": "XP_021331402", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331402" }, "gene_names": [ { "name": "LOC110439604", "type": "recommended", "evidence": [ { "id": "A0A8M9PIY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY0" } ] }, { "name": "LOC110439604", "type": "synonym", "evidence": [ { "id": "XP_021331402", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331402" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PIY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021331402", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331402" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021331402", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331402" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIY0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110439604", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY0", "locus": {} } ], "crossref": [ { "id": "110439604", "url": "https://www.ncbi.nlm.nih.gov/gene/110439604", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR046616", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046616", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110439604", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110439604", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PIY0", "url": "https://www.orthodb.org/?gene=A0A8M9PIY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47773", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47773", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47773:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47773:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021331402", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331402", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PIY0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PWD5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PWD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PWD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PWD5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDPLLPTLSIVDTSVPQDRQQCFLKASKDAKTLASRNRCFERNTSQDKKTACEEAKKRCQHITCAPSEVQYLGQLILNFGKYNGQSFKWLVENDVGYIKYVLDLHIKERRHQGRKEGPGEYIKDLLLQYVQLFPQVSCHLEVNVDSAIYGQGRFRSFTFLEMWQWYSLHKTLQADPQAGSAQEKKMAQEAFCSVRQWLTMKEEDISVKTLKRFRQYILNKEKPLEDRPLPAAAASSSSSGSRGDGGWADDALLVEALSAFEAQAVEDKGSLPKKPLSFPERQGAGEAKRRKRSCEDLSQKPHSDSPLSAAPASTSLLEAPASASLVPGQSSSSAPASASSVPGQSSSSAPASASSFPASASSSAPASASSVPASASSSAPASASSVPASASSSAPASASSVPASASSSAPASASSVPASASSSAPASASVSASDVQPRRSSGGSTHSDPAHSEVLFEGWHKMWESGLHGLPSADILWLKEDAERGLFQRAMAYKDKHGNRKWRKVLKDDRMWFHPPEFPGVVEGKVPSADSFFHSSVFFWRPVGVWRYSLRCPRSDCPARTNQKAFLYRCGYSSTVRQICHMSGWYSMLTEVLACNACRKAAKESEEHTIGRFLSWDQCILNQLSPAHRAVFPAVLTLRRGVDKQVIRLMRDRTEGNTMVKVWRQVQESHCEDYLQRKDLYTTLLSQYNKPGKITRSLCQQFQRPPARREPPSARLMRKAFLISEADNIEDYRTQIMSTFGQVLKYDSTKKICKKLSGDGKGTAEWCTNVANEQGQILISVLTCEESLEKMRPMAEGLMERYRRADEAPPELMYVDRGCCRVHAVSSVEQLFSDWTDRGMLVRLDIFHWIHRFDAALRTDHHPKYALFKSALSAAVFAYNKDDMALLVQAIRAGHPTNYASLTDSQIIELRVSKYDLSHYVRRITVGAQETCARVQCAIDLLKGAAGMDENQVHLFKDSAAIDHVWENQQKHLECIQDPPGRNMYTITKYVTRNGVRLARYSTVRGSNSLEGFHSFLPDMIPGPHCAAVPFQVYLLAGIARWNSNRESASVQGRKGRKHMVYMSPLVHRLNQRCQELFGEVEEANYRPPVPAGDERIGLEYLFSQSSEPFSAPDHYAQTRETLQADEDEDEDVPAGVAEEEEELQEEDDDVGYSSDRERDSLTPLRNRLCLTDQAVAAEFDPCVEDVCGPNHLPGYQHVEDLCKVLVEIALEEGKLALNESTRQKVISAWNKLDLHDRSIQQFDSLYSARWGNALFGRTSGDPTEASLVQKLKFSKRYSAAHLVDSRKNRLMYCLVKQLWLHPGVGGKAKGSPLKQQITKLYQRVQQRVTVDDDQLRKLGIPILKINSKCVSEFIRRQEALSATNVTDQGLSVLRRHQSVSSTSQPPAEELPEERPHTSRPAVQYPITTSLAGTRKLKQRLPQILPVPPSALAQPVPAPAHSMPAGLRHTHTLLTAPPAVSLPQASTPLLLPSRSTVYKRKKAELSGSGHPTSVKVYICALCGQPTQGHKKYRKKSYCESSKASTSTNLAGQTFDCFEDFKRAVDVLLGSQSQASESV", "length": 1558, "header": "tr|A0A8M9PIY0-1|A0A8M9PIY0_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110439604 PE=4 SV=1 CANONICAL=A0A8M9PIY0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PIY0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY0/entry#A0A8M9PIY0-1", "sequence": { "sequence": "MDPLLPTLSIVDTSVPQDRQQCFLKASKDAKTLASRNRCFERNTSQDKKTACEEAKKRCQHITCAPSEVQYLGQLILNFGKYNGQSFKWLVENDVGYIKYVLDLHIKERRHQGRKEGPGEYIKDLLLQYVQLFPQVSCHLEVNVDSAIYGQGRFRSFTFLEMWQWYSLHKTLQADPQAGSAQEKKMAQEAFCSVRQWLTMKEEDISVKTLKRFRQYILNKEKPLEDRPLPAAAASSSSSGSRGDGGWADDALLVEALSAFEAQAVEDKGSLPKKPLSFPERQGAGEAKRRKRSCEDLSQKPHSDSPLSAAPASTSLLEAPASASLVPGQSSSSAPASASSVPGQSSSSAPASASSFPASASSSAPASASSVPASASSSAPASASSVPASASSSAPASASSVPASASSSAPASASSVPASASSSAPASASVSASDVQPRRSSGGSTHSDPAHSEVLFEGWHKMWESGLHGLPSADILWLKEDAERGLFQRAMAYKDKHGNRKWRKVLKDDRMWFHPPEFPGVVEGKVPSADSFFHSSVFFWRPVGVWRYSLRCPRSDCPARTNQKAFLYRCGYSSTVRQICHMSGWYSMLTEVLACNACRKAAKESEEHTIGRFLSWDQCILNQLSPAHRAVFPAVLTLRRGVDKQVIRLMRDRTEGNTMVKVWRQVQESHCEDYLQRKDLYTTLLSQYNKPGKITRSLCQQFQRPPARREPPSARLMRKAFLISEADNIEDYRTQIMSTFGQVLKYDSTKKICKKLSGDGKGTAEWCTNVANEQGQILISVLTCEESLEKMRPMAEGLMERYRRADEAPPELMYVDRGCCRVHAVSSVEQLFSDWTDRGMLVRLDIFHWIHRFDAALRTDHHPKYALFKSALSAAVFAYNKDDMALLVQAIRAGHPTNYASLTDSQIIELRVSKYDLSHYVRRITVGAQETCARVQCAIDLLKGAAGMDENQVHLFKDSAAIDHVWENQQKHLECIQDPPGRNMYTITKYVTRNGVRLARYSTVRGSNSLEGFHSFLPDMIPGPHCAAVPFQVYLLAGIARWNSNRESASVQGRKGRKHMVYMSPLVHRLNQRCQELFGEVEEANYRPPVPAGDERIGLEYLFSQSSEPFSAPDHYAQTRETLQADEDEDEDVPAGVAEEEEELQEEDDDVGYSSDRERDSLTPLRNRLCLTDQAVAAEFDPCVEDVCGPNHLPGYQHVEDLCKVLVEIALEEGKLALNESTRQKVISAWNKLDLHDRSIQQFDSLYSARWGNALFGRTSGDPTEASLVQKLKFSKRYSAAHLVDSRKNRLMYCLVKQLWLHPGVGGKAKGSPLKQQITKLYQRVQQRVTVDDDQLRKLGIPILKINSKCVSEFIRRQEALSATNVTDQGLSVLRRHQSVSSTSQPPAEELPEERPHTSRPAVQYPITTSLAGTRKLKQRLPQILPVPPSALAQPVPAPAHSMPAGLRHTHTLLTAPPAVSLPQASTPLLLPSRSTVYKRKKAELSGSGHPTSVKVYICALCGQPTQGHKKYRKKSYCESSKASTSTNLAGQTFDCFEDFKRAVDVLLGSQSQASESV", "length": 1558, "header": "tr|A0A8M9PIY0-1|A0A8M9PIY0_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110439604 PE=4 SV=1 CANONICAL=A0A8M9PIY0-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PWD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY0/entry#A0A8M9PWD5-1", "sequence": { "sequence": "MDPLLPTLSIVDTSVPQDRQQCFLKASKDAKTLASRNRCFERNTSQDKKTACEEAKKRCQHITCAPSEVQYLGQLILNFGKYNGQSFKWLVENDVGYIKYVLDLHIKERRHQGRKEGPGEYIKDLLLQYVQLFPQVSCHLEVNVDSAIYGQGRFRSFTFLEMWQWYSLHKTLQADPQAGSAQEKKMAQEAFCSVRQWLTMKEEDISVKTLKRFRQYILNKEKPLEDRPLPAAAASSSSSGSRGDGGWADDALLVEALSAFEAQVEDKGSLPKKPLSFPERQGAGEAKRRKRSCEDLSQKPHSDSPLSAAPASTSLLEAPASASLVPGQSSSSAPASASSVPGQSSSSAPASASSFPASASSSAPASASSVPASASSSAPASASSVPASASSSAPASASSVPASASSSAPASASSVPASASSSAPASASVSASDVQPRRSSGGSTHSDPAHSEVLFEGWHKMWESGLHGLPSADILWLKEDAERGLFQRAMAYKDKHGNRKWRKVLKDDRMWFHPPEFPGVVEGKVPSADSFFHSSVFFWRPVGVWRYSLRCPRSDCPARTNQKAFLYRCGYSSTVRQICHMSGWYSMLTEVLACNACRKAAKESEEHTIGRFLSWDQCILNQLSPAHRAVFPAVLTLRRGVDKQVIRLMRDRTEGNTMVKVWRQVQESHCEDYLQRKDLYTTLLSQYNKPGKITRSLCQQFQRPPARREPPSARLMRKAFLISEADNIEDYRTQIMSTFGQVLKYDSTKKICKKLSGDGKGTAEWCTNVANEQGQILISVLTCEESLEKMRPMAEGLMERYRRADEAPPELMYVDRGCCRVHAVSSVEQLFSDWTDRGMLVRLDIFHWIHRFDAALRTDHHPKYALFKSALSAAVFAYNKDDMALLVQAIRAGHPTNYASLTDSQIIELRVSKYDLSHYVRRITVGAQETCARVQCAIDLLKGAAGMDENQVHLFKDSAAIDHVWENQQKHLECIQDPPGRNMYTITKYVTRNGVRLARYSTVRGSNSLEGFHSFLPDMIPGPHCAAVPFQVYLLAGIARWNSNRESASVQGRKGRKHMVYMSPLVHRLNQRCQELFGEVEEANYRPPVPAGDERIGLEYLFSQSSEPFSAPDHYAQTRETLQADEDEDEDVPAGVAEEEEELQEEDDDVGYSSDRERDSLTPLRNRLCLTDQAVAAEFDPCVEDVCGPNHLPGYQHVEDLCKVLVEIALEEGKLALNESTRQKVISAWNKLDLHDRSIQQFDSLYSARWGNALFGRTSGDPTEASLVQKLKFSKRYSAAHLVDSRKNRLMYCLVKQLWLHPGVGGKAKGSPLKQQITKLYQRVQQRVTVDDDQLRKLGIPILKINSKCVSEFIRRQEALSATNVTDQGLSVLRRHQSVSSTSQPPAEELPEERPHTSRPAVQYPITTSLAGTRKLKQRLPQILPVPPSALAQPVPAPAHSMPAGLRHTHTLLTAPPAVSLPQASTPLLLPSRSTVYKRKKAELSGSGHPTSVKVYICALCGQPTQGHKKYRKKSYCESSKASTSTNLAGQTFDCFEDFKRAVDVLLGSQSQASESV", "length": 1557, "header": "tr|A0A8M9PWD5-1|A0A8M9PIY0_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110439604 PE=4 SV=1 CANONICAL=A0A8M9PIY0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 925, "start_aa": "Thr", "end_pos": 925, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr925", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:110439604", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110439604", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1219, "end_pos": 1221, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1365, "end_pos": 1367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PIY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY0" }, { "id": "PF20499", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20499" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF6729", "eco_id": "ECO_0000259", "start_pos": 497, "end_pos": 721, "start_aa": "His", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 925 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1219, "end_pos": 1221 }, { "start_pos": 1365, "end_pos": 1367 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", 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This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021326923.1. 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"type": "recommended", "evidence": [ { "id": "A0A8M9PIY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021331407", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331407" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021331407.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021331407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331407" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIY5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIY5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108184001", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5", "locus": {} } ], "crossref": [ { "id": "A0A8M9PIY5", "url": 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"id": "PTHR23226:SF240", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23226:SF240", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021331407", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331407", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PIY5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PIY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDLQEQTDRMVLKEETHGQNEIDKKQQFEKPQEITTDEKPTLTKKTSLHGRPRKSKSGCNFSCKQCRKSFSQKSNLDVHMRVHTGEKPYTCEQCAQSFSQKQCLKTHMRIHTGEKPFSCKQCGKSFSQKPNLDIHMRVHTGEKPYSCEQCGKSFSQKQSFKTHMRIHTGEKPYTCQQCGKNFRHARNLAAHMRTHTGEKPFSCKQCRKSFSKKANLIAHMRVHTREKPYTCEQFGKSLGKKQDLYIHMRIHMGEKPYTCTECGKSFPHKNTLKHHMRTHTGEKPFACAQCGKSFSTKASLKNHMKVHTGTIVFTCDQCGKSLTRKDTIKRHMQTHSGEDRFRCSECGKGFKCKRSLNTHLKLHNGEQSPQN", "length": 392, "header": "tr|A0A8M9PIY5-1|A0A8M9PIY5_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC108184001 PE=3 SV=2 CANONICAL=A0A8M9PIY5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PIY5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5/entry#A0A8M9PIY5-1", "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDLQEQTDRMVLKEETHGQNEIDKKQQFEKPQEITTDEKPTLTKKTSLHGRPRKSKSGCNFSCKQCRKSFSQKSNLDVHMRVHTGEKPYTCEQCAQSFSQKQCLKTHMRIHTGEKPFSCKQCGKSFSQKPNLDIHMRVHTGEKPYSCEQCGKSFSQKQSFKTHMRIHTGEKPYTCQQCGKNFRHARNLAAHMRTHTGEKPFSCKQCRKSFSKKANLIAHMRVHTREKPYTCEQFGKSLGKKQDLYIHMRIHMGEKPYTCTECGKSFPHKNTLKHHMRTHTGEKPFACAQCGKSFSTKASLKNHMKVHTGTIVFTCDQCGKSLTRKDTIKRHMQTHSGEDRFRCSECGKGFKCKRSLNTHLKLHNGEQSPQN", "length": 392, "header": "tr|A0A8M9PIY5-1|A0A8M9PIY5_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC108184001 PE=3 SV=2 CANONICAL=A0A8M9PIY5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108184001", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108184001", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIY5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIY5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIY5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIY5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIY5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIY5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PIY5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PIY5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PIY5" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 82, "end_pos": 109, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PJ22-1", "uniprot_ac": "A0A8M9PJ22", "uniprot_id": "A0A8M9PJ22_DANRE", "mass": { "chemical_mass": 100571.0, "monoisotopic_mass": 100571.0 }, "refseq": { "ac": "XP_021322236", "name": "alpha-2-macroglobulin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322236" }, "gene_names": [ { "name": "a2m2g", "type": "recommended", "evidence": [ { "id": "A0A8M9PJ22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ22" } ] }, { "name": "LOC108179231", "type": "synonym", "evidence": [ { "id": "XP_021322236", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322236" }, { "id": "A0A8M9PJ22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ22" } ] }, { "name": "si:ch211-212c13.8", "type": "synonym", "evidence": [ { "id": "A0A8M9PJ22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ22" } ] } ], "protein_names": [ { "name": "Alpha-2-macroglobulin", "type": "synonym", "evidence": [ { "id": "A0A8M9PJ22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ22/entry#names_and_taxonomy" } ] }, { "name": "alpha-2-macroglobulin", "type": "synonym", "evidence": [ { "id": "XP_021322236", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322236" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021322236.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322236", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322236" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJ22", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ22" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "a2m2g", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ22", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131118-28", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131118-28", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PJ22", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PJ22", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR001599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108179231", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179231", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PJ22", "url": "https://www.orthodb.org/?gene=A0A8M9PJ22", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412:SF150", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412:SF150", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07678", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07678", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322236", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322236", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PJ22", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJ22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131118-28", "url": "https://zfin.org/ZDB-GENE-131118-28", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSFELSVGADVAPVVRILAYCVLPSENIIAASKSLDIEKCFGNKVSLQFSPAKAVPGEKNTLQLSAQPGSLCGLSAVDQSVLILESGKRLDADKIFSLLPFQYVYYPYSAEDEQPCLPVRPRRSVLTDNVYNSLKSVGLKMASNLAVRVPECLSFRGLTYHRFRDIVMYHTSGRVGLGSSIESSTFDNSAVTIRTIFPETWIWDLAEVGDSGSTEVPVTVPDTITTWETEAFCLSSTGLGLAPPAQLTVFQPFFLELSLPYSIIRGEIFELKATVFNYLSKCIMVKVSPAPSSDYTLKASSDDQYSSCLCANGRQTFKWILTPSVLGVVNVTVSAEAEASQTVCDNEIVSVPERGRIDIVTRSLLVQAEGIEKTETNSWLLCPKGDSLSENVDLTVPKDVIEGSAKSSVSVIGDILGRALQNLHGLLRMPYGCGEQNMAVLSPNIYILQYLENTKQLTSAIREKASSFLKSGYQRQLNYKHFDGAYSTFGYGDGNTWLTAFVLRSFGKAQKYTFIDPQIIQSAKDWLISRRDSDGCFIQQGRLFNNRMKGGVTDNVTMTAYITASLLELETPVTDPVVTKGLSCLRSVIEDVKNTYTTALLAYTFSLARDTNTRQQLFSKLEDLAISDGPLVHWSQSASADDSASLDVEISSYVLLAVLTADSLTTADLGFANRIVSWLVKQQNAYGGFSSTQDTVVALQALSLYATKVFSSDGSSTVTVQSAGDSHHFDVNQDNKLLYQEKQLANVPGKYSIEVKGSACVSVQMAQFYNIPTPTEAKTLSIDAEVEGDCKKTFGQNLMLNVTVTYDGPQNRTNMVIVDIKLLSGFTADTSMLKTQRQSFDSLDFFGHAPVERIDSKDDHVLVYLEEVLKEDPVNLQIGLNQIIQVKNLKPAVIKVYDYYQTSDQSEMEYSSHCE", "length": 915, "header": "tr|A0A8M9PJ22-1|A0A8M9PJ22_DANRE Isoform 1 of Alpha-2-macroglobulin OS=Danio rerio OX=7955 GN=a2m2g PE=3 SV=2 CANONICAL=A0A8M9PJ22-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PJ22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ22/entry#A0A8M9PJ22-1", "sequence": { "sequence": 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Alpha-2-macroglobulin OS=Danio rerio OX=7955 GN=a2m2g PE=3 SV=2 CANONICAL=A0A8M9PJ22-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108179231", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179231", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJ22", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ22" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJ22", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ22" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJ22", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ22" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 330, "end_pos": 332, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" }, { "start_pos": 811, "end_pos": 813, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PJ22", "database": "UniProtKB", "url": 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"field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PJ62-1", "uniprot_ac": "A0A8M9PJ62", "uniprot_id": "A0A8M9PJ62_DANRE", "mass": { "chemical_mass": 38612.0, "monoisotopic_mass": 38612.0 }, "refseq": { "ac": "XP_021327009", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327009" }, "gene_names": [ { "name": "LOC110437722", "type": "recommended", "evidence": [ { "id": "A0A8M9PJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ62" } ] }, { "name": "LOC110437722", "type": "synonym", "evidence": [ { "id": "XP_021327009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327009" } ] } ], "protein_names": [ { "name": "C2H2-type domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PJ62", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ62/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021327009", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327009" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021327009", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327009" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ62#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJ62", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ62" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110437722", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJ62", "locus": {} } ], "crossref": [ { "id": "A0A8M9PJ62", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PJ62", "database": "AlphaFoldDB", "categories": [] }, { "id": "110437722", "url": "https://www.ncbi.nlm.nih.gov/gene/110437722", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050826", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050826", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110437722", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437722", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24377", "database": 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"https://www.ncbi.nlm.nih.gov/protein/XP_002660756" } ] } ], "protein_names": [ { "name": "BMP/retinoic acid-inducible neural-specific protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002660756", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660756" }, { "id": "A0A8M9PJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_002660756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660756" } ] } ], "disease": [ { "disease_id": "DOID:0050865", "recommended_name": { "id": "DOID:0050865", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050865", "name": "tongue squamous cell carcinoma", "description": "A head and neck squamous cell carcinoma that is located_in the tongue." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050865" } ] }, { "disease_id": "DOID:1474", "recommended_name": { "id": "DOID:1474", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1474", "name": "aggressive periodontitis", "description": "A periodontitis that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as dental plaque and dental calculus resulting in inflammation and a loss of periodontium." }, "synonyms": [ { "id": "MONDO:0008226", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008226", "name": "periodontitis, aggressive 1", "description": "A localized aggressive periodontitis, formerly called localized juvenile periodontitis. It is a destructive form of periodontitis characterized by ALVEOLAR BONE LOSS of the MOLARS and INCISORS. Inflammation and loss of PERIODONTIUM that is characterized by rapid attachment loss and bone destruction in the presence of little local factors such as DENTAL PLAQUE and DENTAL CALCULUS. This highly destructive form of periodontitis often occurs in young people and was called early-onset periodontitis, but this disease also appears in old people." }, { "id": "MONDO:0008226", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008226", "name": "periodontitis 1, juvenile", "description": "" }, { "id": "MONDO:0008226", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008226", "name": "periodontitis, aggressive, type 1", "description": "" }, { "id": "MIM:170650", "resource": "MIM", "url": "https://www.omim.org/entry/170650", "name": "Periodontititis, aggressive, 1", "description": "Periodontititis, aggressive, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "1474", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1474" } ] }, { "disease_id": "DOID:3388", "recommended_name": { "id": "DOID:3388", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3388", "name": "periodontal disease", "description": "A mouth disease that is relating to or affecting the structures surrounding and supporting the teeth." }, "synonyms": [ { "id": "DOID:3388", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3388", "name": "disease of supporting structures of teeth", "description": "" }, { "id": "DOID:3388", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3388", "name": "periodontium disorder", "description": "" } ], "unlinked_id_list": [ "DOID:1483", "DOID:3086" ], "evidence": [ { "id": "3388", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3388" } ] }, { "disease_id": "DOID:3393", "recommended_name": { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles." }, "synonyms": [ { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "CHD", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Coronary disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary arteriosclerosis", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary heart disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Ischemic Heart Disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "myocardial ischemia", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, type 3", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the CX3CR1 gene." }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "CX3CR1 coronary artery disease", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease caused by mutation in CX3CR1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease, resistance to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, type 2", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, type 4", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the MEF2A gene." }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "MEF2A coronary artery disease", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease caused by mutation in MEF2A", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, type 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "ADCAD1", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the LRP6 gene." }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "LRP6 coronary artery disease", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease caused by mutation in LRP6", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant type 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant, 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "ADCAD2", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "CHDS8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "CHDS9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the KHDC3L gene." }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "KHDC3L complete hydatidiform mole", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "complete hydatidiform mole caused by mutation in KHDC3L", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform Mole, recurrent, type 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "HYDM2", "description": "" }, { "id": "MIM:608320", "resource": "MIM", "url": "https://www.omim.org/entry/608320", "name": "Coronary artery disease, autosomal dominant, 1", "description": "Coronary artery disease, autosomal dominant, 1" }, { "id": "MIM:610947", "resource": "MIM", "url": "https://www.omim.org/entry/610947", "name": "Coronary artery disease, autosomal dominant, 2", "description": "Coronary artery disease, autosomal dominant, 2" }, { "id": "MIM:614293", "resource": "MIM", "url": "https://www.omim.org/entry/614293", "name": "Hydatidiform mole, recurrent, 2", "description": "Hydatidiform mole, recurrent, 2" } ], "unlinked_id_list": [ "DOID:11840" ], "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ] }, { "disease_id": "DOID:3526", "recommended_name": { "id": "DOID:3526", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3526", "name": "cerebral infarction", "description": "A cerebrovascular disease that is characterized by an area of necrotic tissue in the brain resulting from a blockage or narrowing in the arteries supplying blood and oxygen to the brain." }, "synonyms": [ { "id": "DOID:3526", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3526", "name": "Cerebral infarct", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "obsolete susceptibility to ischemic stroke", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "cerebral infarction, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "ischemic stroke, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "stroke, ischemic, susceptibility to", "description": "" }, { "id": "MONDO:0020671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0020671", "name": "stroke, susceptibility to", "description": "" }, { "id": "MIM:601367", "resource": "MIM", "url": "https://www.omim.org/entry/601367", "name": "Ischemic stroke", "description": "Ischemic stroke" } ], "unlinked_id_list": [], "evidence": [ { "id": "3526", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3526" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:8577", "recommended_name": { "id": "DOID:8577", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8577", "name": "ulcerative colitis", "description": "A colitis that is predominantly confined to the mucosa located_in colon and includes characteristic ulcers, or open sores." }, "synonyms": [ { "id": "DOID:8577", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8577", "name": "Left-sided ulcerative colitis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8577", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8577" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "brinp3b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-121022-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121022-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100330048", "url": "https://www.ncbi.nlm.nih.gov/gene/100330048", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057450", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057450", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100330048", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330048", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMEYEAT", "url": "https://omabrowser.org/oma/group/YMEYEAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PJM5", "url": "https://www.orthodb.org/?gene=A0A8M9PJM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15564", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15564", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15564:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15564:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01823", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01823", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25415", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25415", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002660756", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660756", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PJM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HB04", "url": "https://www.uniprot.org/uniprotkb/A0AC58HB04", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HB04-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HB04-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-121022-1", "url": "https://zfin.org/ZDB-GENE-121022-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MWARSVGPRPPDPMLLWEGMVLCVRWACVLVSVALYVGSAEPLGWLLSDKGPFHRSQEFIEFTERYQHGFTTRYKIYREFGRWKVNSLAAERQEGNGAAVPFDPEFIHNVRLLGRRPSLQKITDTIIKKYGTHFLLSATLGGEESLTIFVDKSKLSRGQQNGDVSNGTGGSLTLEALHQLAASYFIDRDSTLRKLHHLQIASTAIKVTETRTGPLGCSNYDNLDSVSSVLVHSHENKVQLQGLQAILPAYLRSGFVQAALGYIGCNAEGQFVCKDNDCWCQCAAEFPQCNCPEADIHSQESYLERMRDAWRLENQEFQHSDEFQSFMGKLPTQSALNSSRIQQLWRTDSALQQRYRQLESRISLLLSKTRRTANKLFSLSKRCRTQPKIVSLRERPLSYWLQFTLSILYCSENNQLGFYTEELRTCACPYENPSCQSVIPCEVGDGHRCASCSVDNRTRCSSCNPGYVLSHGVCKYAVPNPTDHYLGFETDLQDLELRYLLQHRDGRITTHAIFVSNDVRLNVWFDPSWRKRMLLTLKSNKFKSSRVHMLLGVSVQFCMTKNSTIEPVFSVYVNPFGGSHSESWTMPINQNSYPDWEKTKLDIPLDCFNWTLTLGNRWKSFFETVHFYLRGRIRTESSQGNETVYVEPLEATDASQNFGYMKINSMQLFGYSMHFDPEAIQDLILQLDYPYTQGSQDSALLQLMEIRYRVNRLSPPGPLPLDLFSCLLRHRLKLSSSEVQRILATLQTFSAKQPFYKEYEAAKLCS", "length": 766, "header": "tr|A0A8M9PJM5-1|A0A8M9PJM5_DANRE Isoform 1 of BMP/retinoic acid-inducible neural-specific protein 3 isoform X1 OS=Danio rerio OX=7955 GN=brinp3b PE=3 SV=1 CANONICAL=A0A8M9PJM5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PJM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5/entry#A0A8M9PJM5-1", "sequence": { "sequence": "MWARSVGPRPPDPMLLWEGMVLCVRWACVLVSVALYVGSAEPLGWLLSDKGPFHRSQEFIEFTERYQHGFTTRYKIYREFGRWKVNSLAAERQEGNGAAVPFDPEFIHNVRLLGRRPSLQKITDTIIKKYGTHFLLSATLGGEESLTIFVDKSKLSRGQQNGDVSNGTGGSLTLEALHQLAASYFIDRDSTLRKLHHLQIASTAIKVTETRTGPLGCSNYDNLDSVSSVLVHSHENKVQLQGLQAILPAYLRSGFVQAALGYIGCNAEGQFVCKDNDCWCQCAAEFPQCNCPEADIHSQESYLERMRDAWRLENQEFQHSDEFQSFMGKLPTQSALNSSRIQQLWRTDSALQQRYRQLESRISLLLSKTRRTANKLFSLSKRCRTQPKIVSLRERPLSYWLQFTLSILYCSENNQLGFYTEELRTCACPYENPSCQSVIPCEVGDGHRCASCSVDNRTRCSSCNPGYVLSHGVCKYAVPNPTDHYLGFETDLQDLELRYLLQHRDGRITTHAIFVSNDVRLNVWFDPSWRKRMLLTLKSNKFKSSRVHMLLGVSVQFCMTKNSTIEPVFSVYVNPFGGSHSESWTMPINQNSYPDWEKTKLDIPLDCFNWTLTLGNRWKSFFETVHFYLRGRIRTESSQGNETVYVEPLEATDASQNFGYMKINSMQLFGYSMHFDPEAIQDLILQLDYPYTQGSQDSALLQLMEIRYRVNRLSPPGPLPLDLFSCLLRHRLKLSSSEVQRILATLQTFSAKQPFYKEYEAAKLCS", "length": 766, "header": "tr|A0A8M9PJM5-1|A0A8M9PJM5_DANRE Isoform 1 of BMP/retinoic acid-inducible neural-specific protein 3 isoform X1 OS=Danio rerio OX=7955 GN=brinp3b PE=3 SV=1 CANONICAL=A0A8M9PJM5-1" }, "locus": {} }, { "isoform_ac": "A0AC58HB04-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5/entry#A0AC58HB04-1", "sequence": { "sequence": "MGKLPTQSALNSSRIQQLWRTDSALQQRYRQLESRISLLLSKTRRTANKLFSLSKRCRTQPKIVSLRERPLSYWLQFTLSILYCSENNQLGFYTEELRTCACPYENPSCQSVIPCEVGDGHRCASCSVDNRTRCSSCNPGYVLSHGVCKYAVPNPTDHYLGFETDLQDLELRYLLQHRDGRITTHAIFVSNDVRLNVWFDPSWRKRMLLTLKSNKFKSSRVHMLLGVSVQFCMTKNSTIEPVFSVYVNPFGGSHSESWTMPINQNSYPDWEKTKLDIPLDCFNWTLTLGNRWKSFFETVHFYLRGRIRTESSQGNETVYVEPLEATDASQNFGYMKINSMQLFGYSMHFDPEAIQDLILQLDYPYTQGSQDSALLQLMEIRYRVNRLSPPGPLPLDLFSCLLRHRLKLSSSEVQRILATLQTFSAKQPFYKEYEAAKLCS", "length": 440, "header": "tr|A0AC58HB04-1|A0AC58HB04_DANRE Computationally mapped isoform of BMP/retinoic acid-inducible neural-specific protein 3 isoform X2 OS=Danio rerio OX=7955 GN=brinp3b PE=4 SV=1 CANONICAL=A0A8M9PJM5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100330048", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330048", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q499E0-1", "protein_name": "BMP/retinoic acid-inducible neural-specific protein 3", "gene_name": "Brinp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIWRRRAGAELSSLMALWEWIVLSLHCWVLAVAAVSDQHATSPFDWLLSDKGPFHRSQEYTDFVDRSRQGFSTRYKIYREFGRWKVNNLAVERRNFLGSPLPLAPEFFRNIRLLGRRPTLQQITENLIKKYGTHFLLSATLGGEESLTIFVDKRKLSKRSEGSETSTNSSSVTLETLHQLAASYFIDRDSTLRRLHHIQIASTAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKIQLQGLQVLLPDYLQERFVQAALSYIACNSEGEFICKDNDCWCHCGPKFPECNCPSMDIQAMEENLLRITETWKAYNSDFEDSDEFKFFMKRLPMNYFLNTSTIMHLWTMDSNFQRRYEQLENSMKQLFLKAHRIVHKLFSLSKRCHKQPLISLPRQRTSTYWLTRIQSFLYCNENGLLGSFSEETHSCTCPNDQVVCTAFLPCTVGDASACLTCAPDNRTRCGTCNTGYMLSQGLCKPEVAESTDHYIGFETDLQDLEMKYLLQKTDRRIEVHAIFISNDMRLNSWFDPSWRKRMLLTLKSNKYKSSLVHMILGLSLQICLTKNSTLEPVLAVYVNPFGGSHSESWFMPVSESSFPDWERTKLDLPLQCYNWTLTLGNKWKTFFETVHIYLRSRIKANGPNSNESIYYEPLEFIDPSRNLGYMKINNIQVFGYSMHFDPEAIRDLILQLDYPYTQGSQDSALLQLLEIRDRVNKLSPPGQRRLDLFSCLLRHRLKLSTSEVVRIQSALQAFNAKLPNTVDYDTTKLCS", "length": 766 }, "evidence": [ { "id": "HGNC:22393", "url": "https://alliancegenome.org/gene/HGNC:22393#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q76B58-1", "protein_name": "BMP/retinoic acid-inducible neural-specific protein 3", "gene_name": "BRINP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIWRSRAGAELFSLMALWEWIALSLHCWVLAVAAVSDQHATSPFDWLLSDKGPFHRSQEYTDFVDRSRQGFSTRYKIYREFGRWKVNNLAVERRNFLGSPLPLAPEFFRNIRLLGRRPTLQQITENLIKKYGTHFLLSATLGGEESLTIFVDKRKLSKRAEGSDSTTNSSSVTLETLHQLAASYFIDRDSTLRRLHHIQIASTAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKIQLQGLQVLLPDYLQERFVQAALSYIACNSEGEFICKENDCWCHCGPKFPECNCPSMDIQAMEENLLRITETWKAYNSDFEESDEFKLFMKRLPMNYFLNTSTIMHLWTMDSNFQRRYEQLENSMKQLFLKAQKIVHKLFSLSKRCHKQPLISLPRQRTSTYWLTRIQSFLYCNENGLLGSFSEETHSCTCPNDQVVCTAFLPCTVGDASACLTCAPDNRTRCGTCNTGYMLSQGLCKPEVAESTDHYIGFETDLQDLEMKYLLQKTDRRIEVHAIFISNDMRLNSWFDPSWRKRMLLTLKSNKYKSSLVHMILGLSLQICLTKNSTLEPVLAVYVNPFGGSHSESWFMPVNENSFPDWERTKLDLPLQCYNWTLTLGNKWKTFFETVHIYLRSRIKSNGPNGNESIYYEPLEFIDPSRNLGYMKINNIQVFGYSMHFDPEAIRDLILQLDYPYTQGSQDSALLQLLEIRDRVNKLSPPGQRRLDLFSCLLRHRLKLSTSEVVRIQSALQAFNAKLPNTMDYDTTKLCS", "length": 766 }, "evidence": [ { "id": "HGNC:22393", "url": "https://alliancegenome.org/gene/HGNC:22393#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121022-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121022-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K1M7-1", "protein_name": "BMP/retinoic acid-inducible neural-specific protein 3", "gene_name": "Brinp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIWRRRAGAELSSLMALWEWIVLSLHCWVLAVAAVSDQHATSPFDWLLSDKGPFHRSQEYTDFVDRSRQGFSTRYKIYREFGRWKVNNLAVERRNFLGSPLPLAPEFFRNIRLLGRRPTLQQITENLIKKYGTHFLLSATLGGEESLTIFVDKRKLSKRPEGSETSTNSSSVTLETLHQLAASYFIDRDSTLRRLHHIQIASTAIKVTETRTGPLGCSNYDNLDSVSSVLVQSPENKIQLQGLQVLLPDYLQERFVQAALSYIACNSEGEFICKENDCWCLCGPKFPECNCPSMDIQAMEENLLRITETWKAYNSDFEDSDEFKFFMKRLPMNYFLNTSTIMHLWTMDSNFQRRYEQLENSMKQLFLKAHRIVHKLFSLSKRCHKQPLISLPRQRTSTYWLTRIQSFLYCNENGLLGSFSEETHSCTCPNDQVVCTAFLPCTVGDASACLTCAPDNRTRCGTCNTGYMLSQGLCKPEVAESTDHYIGFETDLQDLEMKYLLQKTDRRIEVHAIFISNDMRLNSWFDPSWRKRMLLTLKSNKYKSSLVHMILGLSLQICLTKNSTLEPVLAVYINPFGGSHSESWFMPVSESSFPDWERTKLDLPLQCYNWTLTLGNKWKTFFETVHIYLRSRIKANGPNSNESIYYEPLEFIDPSRNLGYMKINNIQVFGYSMHFDPEAIRDLILQLDYPYTQGSQDSALLQLLEIRDRVNKLSPPGQRRLDLFSCLLRHRLKLSTSEVVRIQSALQAFNAKLPNTVDYDTTKLCS", "length": 766 }, "evidence": [ { "id": "HGNC:22393", "url": "https://alliancegenome.org/gene/HGNC:22393#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5" } ], "pmid": "" }, { "name": "dendrite", "id": "GO:0030425", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030425", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of neuron differentiation", "id": "GO:0045666", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045666", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5" } ], "pmid": "" }, { "name": "cellular response to retinoic acid", "id": "GO:0071300", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071300", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5" } ], "pmid": "" }, { "name": "negative regulation of mitotic cell cycle", "id": "GO:0045930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045930", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5" } ], "pmid": "" }, { "name": "central nervous system neuron differentiation", "id": "GO:0021953", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0021953", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 337, "end_pos": 339, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 641, "end_pos": 643, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PJM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJM5" }, { "id": "SM00457", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00457" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MACPF", "eco_id": "ECO_0000259", "start_pos": 77, "end_pos": 264, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 166, "end_pos": 168 }, { "start_pos": 337, "end_pos": 339 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 641, "end_pos": 643 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0S686-1", "uniprot_ac": "B0S686", "uniprot_id": "B0S686_DANRE", "mass": { "chemical_mass": 24618.0, "monoisotopic_mass": 24618.0 }, "refseq": { "ac": "NP_001116711", "name": "uncharacterized protein LOC557488 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116711" }, "gene_names": [ { "name": "si:ch211-266a5.12", "type": "recommended", "evidence": [ { "id": "B0S686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S686" } ] }, { "name": "si:ch211-266a5.12", "type": "synonym", "evidence": [ { "id": "NP_001116711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116711" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC557488 precursor", "type": "synonym", "evidence": [ { "id": "B0S686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S686/entry#names_and_taxonomy" } ] }, { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "B0S686", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S686/entry#names_and_taxonomy" } ] }, { "name": "interleukin 41", "type": "synonym", "evidence": [ { "id": "NP_001116711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116711" } ] }, { "name": "uncharacterized protein LOC557488 precursor", "type": "synonym", "evidence": [ { "id": "NP_001116711", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116711" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: MN262468.1, GDQH01034594.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476783 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000004.1. On Apr 11, 2008 this sequence version replaced XP_704382.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001116711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116711" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S686", "url": "https://www.uniprot.org/uniprotkb/B0S686" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-266a5.12", "url": "https://www.uniprot.org/uniprotkb/B0S686", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-210", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-210", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092714", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092714", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "557488", "url": "https://www.ncbi.nlm.nih.gov/gene/557488", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:557488", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557488", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMQGKGF", "url": "https://omabrowser.org/oma/group/YMQGKGF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S686", "url": "https://www.orthodb.org/?gene=B0S686", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001116711", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116711", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TQN3", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TQN3-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S686", "url": "https://www.uniprot.org/uniprotkb/B0S686", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S686-1", "url": "https://www.uniprot.org/uniprotkb/B0S686-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-210", "url": "https://zfin.org/ZDB-GENE-081104-210", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASALQCFYFILMLSIPIRECMMISQDVKCIIKKPCFDLSLLPKMVEHVSKDMIVEDGEKILLRHSYFDKIRKKKTLHSCVLLKVIDLFQDVLIRTEAKSSVHQTENINHHHELINIMFQLKNCLSKKKNQCNKLYNNADTQNNTSTAVPTMKDMTPYQLAVIQLQKLKNAHDKVSTVHVQERVMDELKTLHSYMQGKGFRKILTEESHDVS", "length": 212, "header": "tr|B0S686-1|B0S686_DANRE Isoform 1 of Uncharacterized protein LOC557488 precursor OS=Danio rerio OX=7955 GN=si:ch211-266a5.12 PE=4 SV=1 CANONICAL=B0S686-1" }, "isoforms": [ { "isoform_ac": "A0AB32TQN3-1", "url": "https://www.uniprot.org/uniprotkb/B0S686/entry#A0AB32TQN3-1", "sequence": { "sequence": "MASALQCFYFILMLSIPIRECMMISQDVKCIIKKPCFDLSLLPKMVEHVSKDMKTLHSCVLLKVIDLFQDVLIRTEAKSSVHQTENINHHHELINIMFQLKNCLSKKKNQCNKLYNNADTQNNTSTAVPTMKDMTPYQLAVIQLQKLKNAHDKVSTVHVQERVMDELKTLHSYMQGKGFRKILTEESHDVS", "length": 191, "header": "tr|A0AB32TQN3-1|B0S686_DANRE Computationally mapped isoform of Uncharacterized protein LOC557488 precursor OS=Danio rerio OX=7955 GN=si:ch211-266a5.12 PE=4 SV=1 CANONICAL=B0S686-1" }, "locus": {} }, { "isoform_ac": "B0S686-1", "url": "https://www.uniprot.org/uniprotkb/B0S686/entry#B0S686-1", "sequence": { "sequence": "MASALQCFYFILMLSIPIRECMMISQDVKCIIKKPCFDLSLLPKMVEHVSKDMIVEDGEKILLRHSYFDKIRKKKTLHSCVLLKVIDLFQDVLIRTEAKSSVHQTENINHHHELINIMFQLKNCLSKKKNQCNKLYNNADTQNNTSTAVPTMKDMTPYQLAVIQLQKLKNAHDKVSTVHVQERVMDELKTLHSYMQGKGFRKILTEESHDVS", "length": 212, "header": "tr|B0S686-1|B0S686_DANRE Isoform 1 of Uncharacterized protein LOC557488 precursor OS=Danio rerio OX=7955 GN=si:ch211-266a5.12 PE=4 SV=1 CANONICAL=B0S686-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0S686", "url": "https://www.uniprot.org/uniprotkb/B0S686" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Molecular Evolution of MDM1, a 'Duplication-Resistant' Gene in Vertebrates.", "journal": "PLoS ONE", "date": "2016", "authors": "Hensley MR, Chua RF, Leung YF, Yang JY, Zhang G", "evidence": [ { "database": "UniProtKB", "id": "B0S686", "url": "https://www.uniprot.org/uniprotkb/B0S686" } ], "reference": [ { "type": "PubMed", "id": "27658201", "url": "https://glygen.org/publication/PubMed/27658201" } ] } ], "pathway": [ { "id": "dre:557488", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557488", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 143, "end_pos": 145 }, { "start_pos": 144, "end_pos": 146 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2BGP9-1", "uniprot_ac": "A2BGP9", "uniprot_id": "A2BGP9_DANRE", "mass": { "chemical_mass": 33520.0, "monoisotopic_mass": 33520.0 }, "refseq": { "ac": "NP_001418045", "name": "protein FAM151B isoform a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418045" }, "gene_names": [ { "name": "fam151b", "type": "recommended", "evidence": [ { "id": "A2BGP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGP9" } ] }, { "name": "fam151b", "type": "synonym", "evidence": [ { "id": "NP_001418045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418045" } ] }, { "name": "zgc:100861", "type": "synonym", "evidence": [ { "id": "NP_001418045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418045" }, { "id": "A2BGP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGP9" } ] } ], "protein_names": [ { "name": "Protein FAM151B isoform a", "type": "synonym", "evidence": [ { "id": "A2BGP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGP9/entry#names_and_taxonomy" } ] }, { "name": "protein FAM151B isoform a", "type": "synonym", "evidence": [ { "id": "NP_001418045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418045" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01010133.1, EH548718.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Jun 27, 2024 this sequence version replaced XP_005171893.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001418045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418045" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BGP9", "url": "https://www.uniprot.org/uniprotkb/A2BGP9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam151b", "url": "https://www.uniprot.org/uniprotkb/A2BGP9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040801-38", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-38", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "445137", "url": "https://www.ncbi.nlm.nih.gov/gene/445137", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:445137", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:445137", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A2BGP9", "url": "https://www.orthodb.org/?gene=A2BGP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21184", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21184", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21184:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21184:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10223", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10223", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001418045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418045", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TQW1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TQW1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JID1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JID1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JID1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JID1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JID2", "url": "https://www.uniprot.org/uniprotkb/A0AC58JID2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JID2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JID2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JID3", "url": "https://www.uniprot.org/uniprotkb/A0AC58JID3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JID3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JID3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BGP8", "url": "https://www.uniprot.org/uniprotkb/A2BGP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BGP8-1", "url": "https://www.uniprot.org/uniprotkb/A2BGP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BGP9", "url": "https://www.uniprot.org/uniprotkb/A2BGP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BGP9-1", "url": "https://www.uniprot.org/uniprotkb/A2BGP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040801-38", "url": "https://zfin.org/ZDB-GENE-040801-38", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGLVKHKLYRFIACAAIIASLIVFYLKLQSISKGSMSEQTLEYFLNKGTIRRKDAADIEWYHAANSKSKLIEALRGSAQMIEADVLLRGADPEEPIMAHPPAKDSDITLQDWLKEVVKSDKGIKLDFKSLAAVSQSMSLLEEVRDQLKGPVWINADILPGPGGTATPVDPHVFLQEVAQRSENDVLSLGWTTGWTEDVDNPGYSWEMVHQMEELCRPLKQPVTFPVRASLLPMSFPQFQWLLEQSDRYSLTVWTGKDDALNVNDLMPYRKNLGKRRIYYDLLESQIKQFKALAGYD", "length": 296, "header": "tr|A2BGP9-1|A2BGP9_DANRE Isoform 1 of Protein FAM151B isoform a OS=Danio rerio OX=7955 GN=fam151b PE=1 SV=1 CANONICAL=A2BGP9-1" }, "isoforms": [ { "isoform_ac": "A0AB32TQW1-1", "url": "https://www.uniprot.org/uniprotkb/A2BGP9/entry#A0AB32TQW1-1", "sequence": { "sequence": "MGLVKHKLYRFIACAAIIASLIVFYLKLQSISKGSAQMIEADVLLRGADPEEPIMAHPPAKDSDITLQDWLKEVVKSDKGIKLDFKSLAAVSQSMSLLEEVRDQLKGPVWINADILPGPGGTATPVDPHVFLQEVAQRSENDVLSLGWTTGWTEDVDNPGYSWEMVHQMEELCRPLKQPVTFPVRASLLPMSFPQFQWLLEQSDRYSLTVWTGKDDALNVNDLMPYRKNLGKRRIYYDLLESQIKQFKALAGYD", "length": 254, "header": "tr|A0AB32TQW1-1|A2BGP9_DANRE Computationally mapped isoform of Protein FAM151B isoform a OS=Danio rerio OX=7955 GN=fam151b PE=1 SV=1 CANONICAL=A2BGP9-1" }, "locus": {} }, { "isoform_ac": "A0AC58JID1-1", "url": "https://www.uniprot.org/uniprotkb/A2BGP9/entry#A0AC58JID1-1", "sequence": { "sequence": "MAHPPAKDSDITLQDWLKEVVKSDKGIKLDFKSLAAVSQSMSLLEEVRDQLKGPVWINADILPGPGGTATPVDPHVFLQEVAQRSENDVLSLGWTTGWTEDVDNPGYSWEMVHQMEELCRPLKQPVTFPVRASLLPMSFPQFQWLLEQSDRSEILH", "length": 156, "header": "tr|A0AC58JID1-1|A0AC58JID1_DANRE Computationally mapped isoform of Protein FAM151B isoform X4 OS=Danio rerio OX=7955 GN=fam151b PE=1 SV=1 CANONICAL=A2BGP9-1" }, "locus": {} }, { "isoform_ac": "A0AC58JID2-1", "url": "https://www.uniprot.org/uniprotkb/A2BGP9/entry#A0AC58JID2-1", "sequence": { "sequence": "MIEADVLLRGADPEEPIMAHPPAKDSDITLQDWLKEVVKSDKGIKLDFKSLAAVSQSMSLLEEVRDQLKGPVWINADILPGPGGTATPVDPHVFLQEVAQRSENDVLSLGWTTGWTEDVDNPGYSWEMVHQMEELCRPLKQPVTFPVRASLLPMSFPQFQWLLEQSDRYSLTVWTGKDDALNVNDLMPYRKNLGKRRIYYDLLESQIKQFKALAGYD", "length": 217, "header": "tr|A0AC58JID2-1|A0AC58JID2_DANRE Computationally mapped isoform of Protein FAM151B isoform X2 OS=Danio rerio OX=7955 GN=fam151b PE=1 SV=1 CANONICAL=A2BGP9-1" }, "locus": {} }, { "isoform_ac": "A0AC58JID3-1", "url": "https://www.uniprot.org/uniprotkb/A2BGP9/entry#A0AC58JID3-1", "sequence": { "sequence": "MAHPPAKDSDITLQDWLKEVVKSDKGIKLDFKSLAAVSQSMSLLEEVRDQLKGPVWINADILPGPGGTATPVDPHVFLQEVAQRSENDVLSLGWTTGWTEDVDNPGYSWEMVHQMEELCRPLKQPVTFPVRASLLPMSFPQFQWLLEQSDRYSLTVWTGKDDALNVNDLMPYRKNLGKRRIYYDLLESQIKQFKALAGYD", "length": 200, "header": "tr|A0AC58JID3-1|A0AC58JID3_DANRE Computationally mapped isoform of Protein FAM151B isoform X3 OS=Danio rerio OX=7955 GN=fam151b PE=1 SV=1 CANONICAL=A2BGP9-1" }, "locus": {} }, { "isoform_ac": "A2BGP8-1", "url": "https://www.uniprot.org/uniprotkb/A2BGP9/entry#A2BGP8-1", "sequence": { "sequence": "MGLVKHKLYRFIACAAIIASLIVFYLKLQSISKGSMSEQTLEYFLNKGTIRRKDAADIEWYHAANSKSKLIEALRGSAQMIEADVLLRGADPEEPIMAHPPAKDSDITLQDWLKEVVKSDKGIKLDFKSLAAVSQSMSLLEEVRDQLKGPVWINADILPGPGGTATPVDPHVFLQEVAQRSENDVLSLGWTTGWTEDVDNPGYSWEMVHQMEELCRPLKQPVTFPVRASLLPMSFPQFQWLLEQSDRSEILH", "length": 252, "header": "tr|A2BGP8-1|A2BGP8_DANRE Computationally mapped isoform of Protein FAM151B isoform b OS=Danio rerio OX=7955 GN=fam151b PE=1 SV=1 CANONICAL=A2BGP9-1" }, "locus": {} }, { "isoform_ac": "A2BGP9-1", "url": "https://www.uniprot.org/uniprotkb/A2BGP9/entry#A2BGP9-1", "sequence": { "sequence": "MGLVKHKLYRFIACAAIIASLIVFYLKLQSISKGSMSEQTLEYFLNKGTIRRKDAADIEWYHAANSKSKLIEALRGSAQMIEADVLLRGADPEEPIMAHPPAKDSDITLQDWLKEVVKSDKGIKLDFKSLAAVSQSMSLLEEVRDQLKGPVWINADILPGPGGTATPVDPHVFLQEVAQRSENDVLSLGWTTGWTEDVDNPGYSWEMVHQMEELCRPLKQPVTFPVRASLLPMSFPQFQWLLEQSDRYSLTVWTGKDDALNVNDLMPYRKNLGKRRIYYDLLESQIKQFKALAGYD", "length": 296, "header": "tr|A2BGP9-1|A2BGP9_DANRE Isoform 1 of Protein FAM151B isoform a OS=Danio rerio OX=7955 GN=fam151b PE=1 SV=1 CANONICAL=A2BGP9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2002", "authors": "Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA", "evidence": [ { "database": "UniProtKB", "id": "A2BGP8", "url": "https://www.uniprot.org/uniprotkb/A2BGP8" } ], "reference": [ { "type": "PubMed", "id": "12477932", "url": "https://glygen.org/publication/PubMed/12477932" } ] }, { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "A2BGP8", "url": "https://www.uniprot.org/uniprotkb/A2BGP8" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] } ], "pathway": [ { "id": "dre:445137", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:445137", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABZ3NNM5-1", "protein_name": "Family with sequence similarity 151, member B", "gene_name": "Fam151b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASAGGPGSWSENILTYFLRNRQITAEDGAEILWYHAANHKCQMSDALKSAAHMIEADVLLPSDGSEHGQPIMAHPPETGSDNTLQEWLAEVTKSNKGIKLDFKSLAAARASMLFLDNVKQHLQRPVWINADVLPGPNGSSKVVDAKAFLDTVTSFFPDVTFSLGWTTGWHPEKVNEGYTWPMVKEMDYICSELTQPVTFPVRAALVRQSCSQLLWLLTKSSRYSLTVWTGKDDIYPTEDLLYIRDCFNKTQVFYDILEPQNYEFKQAIGIRHSLRI", "length": 278 }, "evidence": [ { "id": "HGNC:33716", "url": "https://alliancegenome.org/gene/HGNC:33716#orthology", "database": "AGR" }, { "id": "MGI:1921192", "url": "https://alliancegenome.org/gene/MGI:1921192#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3YUE4-1", "protein_name": "Protein FAM151B", "gene_name": "Fam151b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAACAGGPGSWSENILKYFLRNNQITAEDGAEILWSHAANHKSQMNEALKSAAHMIEADVLLPSDGSEHGQPIMAHPPETSSDNTLQEWLAEVVKSNKGIKLDFKSLAAVRASMLFLDNMKQHLQRPVWINADILPGPNGSSKVVDAKAFLDTVTSFFPDVTFSLGWTTGWHPEKVNEGYSWSMVKEMDYICSELTQPVTFPVRAALVRQSCPQLLWLLTKSNRYSLTVWTGKDDIYSTEDLLYIRDYFNKTQVFYDISEPQNHEFKQAIGIRGHSLRI", "length": 279 }, "evidence": [ { "id": "HGNC:33716", "url": "https://alliancegenome.org/gene/HGNC:33716#orthology", "database": "AGR" }, { "id": "MGI:1921192", "url": "https://alliancegenome.org/gene/MGI:1921192#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-38", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-38#orthology", "database": "AGR" }, { "id": "A2BGP9", "url": "https://omabrowser.org/oma/group/A2BGP9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UXP7-1", "protein_name": "Protein FAM151B", "gene_name": "FAM151B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASAGGPGSWSENILEYFLRNSQITAEDGAEITWYHAANHKAQTNEALKSTAHMIEADVLLPSDGSEHSQPIMAHPPETNSDNTLQEWLTEVMKSNKGIKLDFKSLAVVEPSMMLLENVKRHLKRPVWINADILPGPNGNSKVIDAKPFLDTVISFFPDVTFSLGWTTGWHPEKVNEGYSWTMVKEMEYICNELSQPVTFPVRAALVRQSCSQLLWLLKKSNRYSLTIWTGKNDNYSVEDLLYIRDHFDKKQVFYDILEPQNHEFKQAIGIKVNL", "length": 276 }, "evidence": [ { "id": "HGNC:33716", "url": "https://alliancegenome.org/gene/HGNC:33716#orthology", "database": "AGR" }, { "id": "MGI:1921192", "url": "https://alliancegenome.org/gene/MGI:1921192#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-38", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-38#orthology", "database": "AGR" }, { "id": "A2BGP9", "url": "https://omabrowser.org/oma/group/A2BGP9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VLU9-1", "protein_name": "Menorin-like domain-containing protein", "gene_name": "Dmel\\CG7231", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDSKITFLLTTLLFVLVAKINGSALNASNYQYQVVVEQTAPDDSQIEYIFLKQSDMMKVWGTNLTAITWAHAVNSQQLLDEVLTETSGIDFIEADIVLGKLNGDGEDMPIMAHPPANVSDLTLSEFLNQIINFNRDHEDQKKGVKLDFKSIEVFEGSLDILDVNIPNVSLPTTYPVWINADILSGPVEQNRTVPVDADRFFAGCMRYKQAVLSIGWTTNWGADFRDGEYTQQQCDDMLETLSENNVLSTGQAITFPVRAGIAANSEEQLHRLVAAVNETNESTLTIWSSAGDYVDVDKLRKLIFSFGLDRVYLDVPEELASQLNLDNPGNGASTFKSLFGFSFMSLCFWALSSWMQRL", "length": 358 }, "evidence": [ { "id": "HGNC:33716", "url": "https://alliancegenome.org/gene/HGNC:33716#orthology", "database": "AGR" }, { "id": "MGI:1921192", "url": "https://alliancegenome.org/gene/MGI:1921192#orthology", "database": "AGR" }, { "id": "A2BGP9", "url": "https://omabrowser.org/oma/group/A2BGP9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A2BGP9", "url": "https://www.uniprot.org/uniprotkb/A2BGP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A2BGP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGP9" }, { "id": "PF10223", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10223" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Menorin-like", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 285, "start_aa": "Asp", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5PF14-1", "uniprot_ac": "A5PF14", "uniprot_id": "A5PF14_DANRE", "mass": { "chemical_mass": 94522.0, "monoisotopic_mass": 94522.0 }, "refseq": { "ac": "NP_001073437", "name": "uncharacterized protein LOC558115", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073437" }, "gene_names": [ { "name": "zgc:153738", "type": "recommended", "evidence": [ { "id": "A5PF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PF14" } ] }, { "name": "zgc:153738", "type": "synonym", "evidence": [ { "id": "NP_001073437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073437" }, { "id": "A5PF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PF14" } ] } ], "protein_names": [ { "name": "IQ and AAA domain-containing protein-like", "type": "synonym", "evidence": [ { "id": "NP_001073437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073437" } ] }, { "name": "Uncharacterized protein LOC558115", "type": "synonym", "evidence": [ { "id": "A5PF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PF14/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC558115", "type": "synonym", "evidence": [ { "id": "NP_001073437", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073437" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01017595.1, SRR32588732.9316712.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Nov 20, 2014 this sequence version replaced NP_001073437.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001073437", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073437" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PF14", "url": "https://www.uniprot.org/uniprotkb/A5PF14" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A5PF14", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061013-622", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061013-622", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000069230", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000069230", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19506", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19506", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "558115", "url": "https://www.ncbi.nlm.nih.gov/gene/558115", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003959", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003959", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558115", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558115", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VCHETGA", "url": "https://omabrowser.org/oma/group/VCHETGA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5PF14", "url": "https://www.orthodb.org/?gene=A5PF14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14690:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14690:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00004", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00004", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00612", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00612", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001073437", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073437", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TUP6", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUP6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TUP6-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUP6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G7C9", "url": "https://www.uniprot.org/uniprotkb/A0AC58G7C9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G7C9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G7C9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G7D3", "url": "https://www.uniprot.org/uniprotkb/A0AC58G7D3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G7D3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G7D3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PF14", "url": "https://www.uniprot.org/uniprotkb/A5PF14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PF14-1", "url": "https://www.uniprot.org/uniprotkb/A5PF14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061013-622", "url": "https://zfin.org/ZDB-GENE-061013-622", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSHSTYNSLWSEAHEELSCLLPQELPEEPIRPERDRVVFFQRIATFYVRYVQIFRHLEEAYDQSVHPQKRRVIRQVLDSVMGRVLELKNEMVEKEFSEYHYMDDVIQDLKLTPEDLEIPIPRYFIRERNKVLQDRERMFAAILNQMDVMEKSGPPVMRMLTLERTIKVIQVAERARQGRLRAKFMREIHRDSERQKRADIETVSSDQAAVCIQKVWRGFMQRKITKRLREEEMIFLGMALDPKLSYPSQTELIAQNNKALRRTRQEEHEDDYQKSIGSVVHQLREVEGSEMKETMKDQIRQWFIECRDATGSFPDYPEEEDGGSALIFAEKTPEELAEELAAKEEEDANKNPKGKEDTKEKAKKGKIEDEEEEPGLKMLPSACLPDLERSHKTYSEVWKNRNESKNFSQRHELELIKEDKRKEIEVEIRKQVDELMRQELANWKLAVDKEKSGKVKGAAKKKKASKSAKRKKKDKDLTADRTTESLFEELVEQELLKKPENVKLKDYLGDYSYLGTTLRQSDIEPMPSLSDVRQVVALYAILPLGSQAVHEKSPLVKTILLVGPSGVGKKMLVHAICQETGANLFDLSPLNVAKKYPGRNGLQMMLHLVFKVARLMQPSVIWIGDAEKMFYRKVPKEEKELDPKRLKKDLPKILKSIRGEDCVLIVGTTSDPHSADLKSLCKFYNKIILIPRPDYASRYVMWKELIKKNGGEVTGDLDLSSLAKISDGYTQGHMVQVVRSILTERRIQQFPKRPLTASEFVSPLARIDPVFQEEEEALKNWYAKTPLGKKRIKAASGKEGDEEPPKTGGKAGKKKGKK", "length": 818, "header": "tr|A5PF14-1|A5PF14_DANRE Isoform 1 of Uncharacterized protein LOC558115 OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A5PF14-1" }, "isoforms": [ { "isoform_ac": "A0AB32TUP6-1", "url": "https://www.uniprot.org/uniprotkb/A5PF14/entry#A0AB32TUP6-1", "sequence": { "sequence": "MGRVLELKNEMVEKEFSEYHYMDDVIQDLKLTPEDLEIPIPRYFIRERNKVLQDRERMFAAILNQMDVMEKSGPPVMRMLTLERTIKVIQVAERARQGRLRAKFMREIHRDSERQKRADIETVSSDQAAVCIQKVWRGFMQRKITKRLREEEMIFLGMALDPKLSYPSQTELIAQNNKALRRTRQEEHEDDYQKSIGSVVHQLREVEGSEMKETMKDQIRQWFIECRDATGSFPDYPEEEDGGSALIFAEKTPEELAEELAAKEEEDANKNPKGKEDTKEKAKKGKIEDEEEEPGLKMLPSACLPDLERSHKTYSEVWKNRNESKNFSQRHELELIKEDKRKEIEVEIRKQVDELMRQELANWKLAVDKEKSGKVKGAAKKKKASKSAKRKKKDKDLTADRTTESLFEELVEQELLKKPENVKLKDYLGDYSYLGTTLRQSDIEPMPSLSDVRQVVALYAILPLGSQAVHEKSPLVKTILLVGPSGVGKKMLVHAICQETGANLFDLSPLNVAKKYPGRNGLQMMLHLVFKVARLMQPSVIWIGDAEKMFYRKVPKEEKELDPKRLKKDLPKILKSIRGEDCVLIVGTTSDPHSADLKSLCKFYNKIILIPRPDYASRYVMWKELIKKNGGEVTGDLDLSSLAKISDGYTQGHMVQVVRSILTERRIQQFPKRPLTASEFVSPLARIDPVFQEEEEALKNWYAKTPLGKKRIKAASGKEGDEEPPKTGGKAGKKKGKK", "length": 738, "header": "tr|A0AB32TUP6-1|A5PF14_DANRE Computationally mapped isoform of Uncharacterized protein LOC558115 OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A5PF14-1" }, "locus": {} }, { "isoform_ac": "A0AC58G7C9-1", "url": "https://www.uniprot.org/uniprotkb/A5PF14/entry#A0AC58G7C9-1", "sequence": { "sequence": "MSHSTYNSLWSEAHEELSCLLPQELPEEPIRPERDRVVFFQRIATFYVRYVQIFRHLEEAYDQSVHPQKRRVIRQVLDSVMGRVLELKNEMVEKEFSEYHYMDDVIQDLKLTPEDLEIPIPRYFIRERNKVLQDRERMFAAILNQMDVMEKSGPPVMRMLTLERTIKVIQVAERARQGRLRAKFMREIHRDSERQKRADIETVSSDQAAVCIQKVWRGFMQRKITKRLREEEMIFLGMALDPKLSYPSQTELIAQNNKALRRTRQEEHEDDYQKSIGSVVHQLREVEGSEMKETMKDQIRQWFIECRDATGSFPDYPEEEDGGSALIFAEKTPEELAEELAAKEEEDANKNPKGKEDTKEKAKKGKIEDEEEEPGLKMLPSACLPDLERSHKTYSEVWKNRNESKNFSQRHELELIKEDKRKEIEVEIRKQVDELMRQELANWKLAVDKEKSGKVKGAAKVQKRRRQKAQRGRRRTKILQQIGSQAVHEKSPLVKTILLVGPSGVGKKMLVHAICQETGANLFDLSPLNVAKKYPGRNGLQMMLHLVFKVARLMQPSVIWIGDAEKMFYRKVPKEEKELDPKRLKKDLPKILKSIRGEDCVLIVGTTSDPHSADLKSLCKFYNKIILIPRPDYASRYVMWKELIKKNGGEVTGDLDLSSLAKISDGYTQGHMVQVVRSILTERRIQQFPKRPLTASEFVSPLARIDPVFQEEEEALKNWYAKTPLGKKRIKAASGKEGDEEPPKTGGKAGKKKGKK", "length": 756, "header": "tr|A0AC58G7C9-1|A0AC58G7C9_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=zgc:153738 PE=4 SV=1 CANONICAL=A5PF14-1" }, "locus": {} }, { "isoform_ac": "A0AC58G7D3-1", "url": "https://www.uniprot.org/uniprotkb/A5PF14/entry#A0AC58G7D3-1", "sequence": { "sequence": "MGRVLELKNEMVEKEFSEYHYMDDVIQDLKLTPEDLEIPIPRYFIRERNKVLQDRERMFAAILNQMDVMEKSGPPVMRMLTLERTIKVIQVAERARQGRLRAKFMREIHRDSERQKRADIETVSSDQAAVCIQKVWRGFMQRKITKRLREEEMIFLGMALDPKLSYPSQTELIAQNNKALRRTRQEEHEDDYQKSIGSVVHQLREVEGSEMKETMKDQIRQWFIECRDATGSFPDYPEEEDGGSALIFAEKTPEELAEELAAKEEEDANKNPKGKEDTKEKAKKGKIEDEEEEPGLKMLPSACLPDLERSHKTYSEVWKNRNESKNFSQRHELELIKEDKRKEIEVEIRKQVDELMRQELANWKLAVDKEKSGKVKGAAKVQKRRRQKAQRGRRRTKILQQIGSQAVHEKSPLVKTILLVGPSGVGKKMLVHAICQETGANLFDLSPLNVAKKYPGRNGLQMMLHLVFKVARLMQPSVIWIGDAEKMFYRKVPKEEKELDPKRLKKDLPKILKSIRGEDCVLIVGTTSDPHSADLKSLCKFYNKIILIPRPDYASRYVMWKELIKKNGGEVTGDLDLSSLAKISDGYTQGHMVQVVRSILTERRIQQFPKRPLTASEFVSPLARIDPVFQEEEEALKNWYAKTPLGKKRIKAASGKEGDEEPPKTGGKAGKKKGKK", "length": 676, "header": "tr|A0AC58G7D3-1|A0AC58G7D3_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=zgc:153738 PE=4 SV=1 CANONICAL=A5PF14-1" }, "locus": {} }, { "isoform_ac": "A5PF14-1", "url": "https://www.uniprot.org/uniprotkb/A5PF14/entry#A5PF14-1", "sequence": { "sequence": "MSHSTYNSLWSEAHEELSCLLPQELPEEPIRPERDRVVFFQRIATFYVRYVQIFRHLEEAYDQSVHPQKRRVIRQVLDSVMGRVLELKNEMVEKEFSEYHYMDDVIQDLKLTPEDLEIPIPRYFIRERNKVLQDRERMFAAILNQMDVMEKSGPPVMRMLTLERTIKVIQVAERARQGRLRAKFMREIHRDSERQKRADIETVSSDQAAVCIQKVWRGFMQRKITKRLREEEMIFLGMALDPKLSYPSQTELIAQNNKALRRTRQEEHEDDYQKSIGSVVHQLREVEGSEMKETMKDQIRQWFIECRDATGSFPDYPEEEDGGSALIFAEKTPEELAEELAAKEEEDANKNPKGKEDTKEKAKKGKIEDEEEEPGLKMLPSACLPDLERSHKTYSEVWKNRNESKNFSQRHELELIKEDKRKEIEVEIRKQVDELMRQELANWKLAVDKEKSGKVKGAAKKKKASKSAKRKKKDKDLTADRTTESLFEELVEQELLKKPENVKLKDYLGDYSYLGTTLRQSDIEPMPSLSDVRQVVALYAILPLGSQAVHEKSPLVKTILLVGPSGVGKKMLVHAICQETGANLFDLSPLNVAKKYPGRNGLQMMLHLVFKVARLMQPSVIWIGDAEKMFYRKVPKEEKELDPKRLKKDLPKILKSIRGEDCVLIVGTTSDPHSADLKSLCKFYNKIILIPRPDYASRYVMWKELIKKNGGEVTGDLDLSSLAKISDGYTQGHMVQVVRSILTERRIQQFPKRPLTASEFVSPLARIDPVFQEEEEALKNWYAKTPLGKKRIKAASGKEGDEEPPKTGGKAGKKKGKK", "length": 818, "header": "tr|A5PF14-1|A5PF14_DANRE Isoform 1 of Uncharacterized protein LOC558115 OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A5PF14-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Systematic discovery of novel ciliary genes through functional genomics in the zebrafish.", "journal": "Development", "date": "2014", "authors": "Choksi Semil P, Babu Deepak, Lau Doreen, Yu Xianwen, Roy Sudipto", "evidence": [ { "database": "UniProtKB", "id": "A5PF14", "url": "https://www.uniprot.org/uniprotkb/A5PF14" } ], "reference": [ { "type": "PubMed", "id": "25139857", "url": "https://glygen.org/publication/PubMed/25139857" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A5PF14", "url": "https://www.uniprot.org/uniprotkb/A5PF14" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:558115", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558115", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A5PF14", "url": "https://www.uniprot.org/uniprotkb/A5PF14" } ], "pmid": "" }, { "name": "ATP hydrolysis activity", "id": "GO:0016887", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016887", "evidence": [ { "database": "UniProtKB", "id": "A5PF14", "url": "https://www.uniprot.org/uniprotkb/A5PF14" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "anatomical structure morphogenesis", "id": "GO:0009653", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009653", "evidence": [ { "database": "UniProtKB", "id": "A5PF14", "url": "https://www.uniprot.org/uniprotkb/A5PF14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 402, "end_pos": 404, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5PF14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PF14" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 555, "end_pos": 694, "start_aa": "Leu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 402, "end_pos": 404 }, { "start_pos": 406, "end_pos": 408 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5WVU6-1", "uniprot_ac": "A5WVU6", "uniprot_id": "TM236_DANRE", "mass": { "chemical_mass": 39208.0, "monoisotopic_mass": 39208.0 }, "refseq": { "ac": "NP_001093549", "name": "transmembrane protein 236", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093549" }, "gene_names": [ { "name": "tmem236", "type": "recommended", "evidence": [ { "id": "A5WVU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVU6" } ] }, { "name": "si:dkey-32m20.1", "type": "synonym", "evidence": [ { "id": "NP_001093549", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093549" }, { "id": "A5WVU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVU6" } ] }, { "name": "tmem236", "type": "synonym", "evidence": [ { "id": "NP_001093549", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093549" } ] } ], "protein_names": [ { "name": "Transmembrane protein 236", "type": "recommended", "evidence": [ { "id": "A5WVU6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVU6/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 236", "type": "synonym", "evidence": [ { "id": "NP_001093549", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093549" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CD015629.1, SRR32588728.22823185.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476757, SAMEA4476784 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000002.1. On Jul 26, 2007 this sequence version replaced XP_001342269.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001093549", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093549" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WVU6", "url": "https://www.uniprot.org/uniprotkb/A5WVU6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmem236", "url": "https://www.uniprot.org/uniprotkb/A5WVU6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-455", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-455", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A5WVU6", "url": "https://alphafold.ebi.ac.uk/entry/A5WVU6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000075715", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000075715", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100002496", "url": "https://www.ncbi.nlm.nih.gov/gene/100002496", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020394", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020394", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100002496", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100002496", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTFPCFA", "url": "https://omabrowser.org/oma/group/CTFPCFA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5WVU6", "url": "https://www.orthodb.org/?gene=A5WVU6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31453:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31453:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR:A5WVU6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A5WVU6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001093549", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093549", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TUY7", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TUY7-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G7K4", "url": "https://www.uniprot.org/uniprotkb/A0AC58G7K4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G7K4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G7K4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G7L4", "url": "https://www.uniprot.org/uniprotkb/A0AC58G7L4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G7L4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G7L4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WVU6", "url": "https://www.uniprot.org/uniprotkb/A5WVU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WVU6-1", "url": "https://www.uniprot.org/uniprotkb/A5WVU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-455", "url": "https://zfin.org/ZDB-GENE-070705-455", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLSGKTVKLIVFELLQFACLCIPVFVVMERFASVIRFVKSSDTAYWLVVAASVAYAASVTLFVWVPLKYFMLKTQRFSEVTNWRPVTLAYVILSTLPCFAIIIASSKVQADAAIRFDRLTELPVSLVLFSLICVDIVERIRPLRLTGKASGLDLDLEMPGPVLTHLEQVTSISGHLQANGQDGDASFRSPVSNGSLSGRWEDARTYGLPRTSSSAYLYSHSHSGPFSFLWKRDPRHDLFVSSFMFWLDTVEMVRVAGTNSVFYSGWVFPIYILAYLSLLRVVITPDSPLLALSSILSQDLPFLVVRICLLAVFGYVTPVLYILKNILASISFVYFVFMTKLKLLNRGSMF", "length": 350, "header": "sp|A5WVU6-1|TM236_DANRE Isoform 1 of Transmembrane protein 236 OS=Danio rerio OX=7955 GN=tmem236 PE=3 SV=1 CANONICAL=A5WVU6-1" }, "isoforms": [ { "isoform_ac": "A0AB32TUY7-1", "url": "https://www.uniprot.org/uniprotkb/A5WVU6/entry#A0AB32TUY7-1", "sequence": { "sequence": "MLSGKTVKLIVFELLQFACLCIPVFVVMERFASVIRFVKSSDTAYWLVVAASVAYAASVTLFVWVPLKYFMLKTQRFSEVTNWRPVTLAYVILSTLPCFAIIIASSKVQADAAIRFDRLTELPVSLVLFSLICVDIVERIRPLRLTGKASGLDLDLEMPGPVLTHLEQVTSISGHLQANGQDGDASFRSPVSNGSLSGRWEDARTYGLPRTSSSAYLYSHSHSGPFSFLWKRDPRHDLFVSSFMFWLDTVEMVRVAGTNSVFYSGWVFPIYILAYLSLLRVVITPDSPLLALSSILSQDLPFLVVRICLLAVFGYVTPVLYILKNILASISFVYFVFMTKLKLLNRGSMF", "length": 350, "header": "tr|A0AB32TUY7-1|TM236_DANRE Computationally mapped isoform of Transmembrane protein 236 OS=Danio rerio OX=7955 GN=tmem236 PE=3 SV=1 CANONICAL=A5WVU6-1" }, "locus": {} }, { "isoform_ac": "A0AC58G7K4-1", "url": "https://www.uniprot.org/uniprotkb/A5WVU6/entry#A0AC58G7K4-1", "sequence": { "sequence": "MLSGKTVKLIVFELLQFACLCIPVFVVMERFASVIRFVKSSDTAYWLVVAASVAYAASVTLFVWVPLKYFMLKTQRFSEVTNWRPVTLAYVILSTLPCFAIIIASSKVQADAAIRFDRLTELPVSLVLFSLICVDIVERIRPLRLTGKASGLDLDLEMPGPVLTHLEQVTSISGHLQANGQDGDASFRSPVSNGSLSGRWEDARTYGLPRTSSSAYLYSHSHSGPFSFLWKRDPRHDLFVSSFMFWLDTVEMVRVAGTNSVFYSGWVFPIYILAYLSLLRVVITPDSPLLALSSILSQDLPFLVVRICLLAVFGYVTPVLYILKNILASISFVYFVFMTKLKLLNRGSMF", "length": 350, "header": "tr|A0AC58G7K4-1|A0AC58G7K4_DANRE Computationally mapped isoform of Transmembrane protein 236 isoform X1 OS=Danio rerio OX=7955 GN=tmem236 PE=4 SV=1 CANONICAL=A5WVU6-1" }, "locus": {} }, { "isoform_ac": "A0AC58G7L4-1", "url": "https://www.uniprot.org/uniprotkb/A5WVU6/entry#A0AC58G7L4-1", "sequence": { "sequence": "MLSGKTVKLIVFELLQFACLCIPVFVVMERFASVIRFVKSSDTAYWLVVAASVAYAASVTLFVWVPLKYFMLKTQRFSEVTNWRPVTLAYVILSTLPCFAIIIASSKVQADAAIRFDRLTELPVSLVLFSLICVDIVERIRPLRLTGKASGLDLDLEMPGPVLTHLEQVTSISGHLQANGQDGDASFRSPVSNGSLSGRWEDARTYGLPRTSSSAYLYSHSHSGPFSFLWKRDPRHDLFVSSFMFWLDTVEMVRVAGTNSVFYSGWVFPIYILAYLSLLRVVITPDSPLLALSSILSQDLPFLVVRICLLAVFGYVTPVLYILKNILASISFVYFVFMTKLKLLNRGSMF", "length": 350, "header": "tr|A0AC58G7L4-1|A0AC58G7L4_DANRE Computationally mapped isoform of Transmembrane protein 236 isoform X1 OS=Danio rerio OX=7955 GN=tmem236 PE=4 SV=1 CANONICAL=A5WVU6-1" }, "locus": {} }, { "isoform_ac": "A5WVU6-1", "url": "https://www.uniprot.org/uniprotkb/A5WVU6/entry#A5WVU6-1", "sequence": { "sequence": "MLSGKTVKLIVFELLQFACLCIPVFVVMERFASVIRFVKSSDTAYWLVVAASVAYAASVTLFVWVPLKYFMLKTQRFSEVTNWRPVTLAYVILSTLPCFAIIIASSKVQADAAIRFDRLTELPVSLVLFSLICVDIVERIRPLRLTGKASGLDLDLEMPGPVLTHLEQVTSISGHLQANGQDGDASFRSPVSNGSLSGRWEDARTYGLPRTSSSAYLYSHSHSGPFSFLWKRDPRHDLFVSSFMFWLDTVEMVRVAGTNSVFYSGWVFPIYILAYLSLLRVVITPDSPLLALSSILSQDLPFLVVRICLLAVFGYVTPVLYILKNILASISFVYFVFMTKLKLLNRGSMF", "length": 350, "header": "sp|A5WVU6-1|TM236_DANRE Isoform 1 of Transmembrane protein 236 OS=Danio rerio OX=7955 GN=tmem236 PE=3 SV=1 CANONICAL=A5WVU6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "A5WVU6", "url": "https://www.uniprot.org/uniprotkb/A5WVU6" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:100002496", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100002496", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2ARJ3-1", "protein_name": "Transmembrane protein 236", "gene_name": "Tmem236", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASGKIIKLVVFELLEFAAFSIPTLVIMEQFATANQRTKSERTHYWLIVSCSIAYVAVVSLLIWVPVKVVLYKKRHLYKKIIGWRPVLVMCVVLTTLPSFSFSIAVTEVQKNINGSANSLPESLPDLPVSLVLLSLIVVDIIEKLRQYPLRGSQKGYEDNDICITSLQQIKTVTEQVVQSDGNPASAQAAKPTAMSQPRNHVAVLAGPLEPSFQSRILRTMSQRDVRAELFLRSFLMWADTVEMLRVAGHQAVYKSAWLYPVYIFSFISLLRMVFTPKNPLLNSLGILMQDLPFVFLRLSLILALGTITPVLGLCKNVLVTISYIYFNYVTKLRPFSAFETSPF", "length": 344 }, "evidence": [ { "id": "RGD:1590637", "url": "https://alliancegenome.org/gene/RGD:1590637#orthology", "database": "AGR" }, { "id": "MGI:1919309", "url": "https://alliancegenome.org/gene/MGI:1919309#orthology", "database": "AGR" }, { "id": "HGNC:23473", "url": "https://alliancegenome.org/gene/HGNC:23473#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-455", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-455#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A3Y5-1", "protein_name": "Transmembrane protein 236", "gene_name": "Tmem236", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASGKIIKLVVFELLEFAAFSVPTLVIMEQFATAYQGTKNGSERTHYWLIVSCSIAYVAGVSLLIWVPIKVVLYKKRHLYKKIIGWRPVLVMCVVLTTLPSFSFSIAVTEVQKNINGSANLLSDSLPDLPVSLVLLSLIVVDIIEKLRIYPLRGSQMGYENNDICVTSLQQIKTVTEQVVRSDENPASAQAAKPNVMPQPRNQVTVLAGPMEPSFQSGILRTMSQRDVRAELFLRSFLMWSDTVEMVRVAGHPAVFKSGWLYPVYIFSFISLLRMVFTPKNPLLSSLGILMQDLPFIFLRLSLIIALGTITPVLGLCKNVLVTMSYIYFNYVTKLRPFSAFETSPF", "length": 346 }, "evidence": [ { "id": "RGD:1590637", "url": "https://alliancegenome.org/gene/RGD:1590637#orthology", "database": "AGR" }, { "id": "MGI:1919309", "url": "https://alliancegenome.org/gene/MGI:1919309#orthology", "database": "AGR" }, { "id": "HGNC:23473", "url": "https://alliancegenome.org/gene/HGNC:23473#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-455", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-455#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5W0B7-1", "protein_name": "Transmembrane protein 236", "gene_name": "TMEM236", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASGRLIKFVVFELLEFAAFSIPTLVITEQFATAYQGTRARSDNTHYWLIISCSIAYVALVTLLIWVPVKVILHKKRYIYRKIKGWRPVLMMCVVLTTLPCLTFSIAVTEVQKSINGSADVLPDMLPDLPVSLVLLSLIMVDIIEKLRIYPLRGSQKSSENGHIHSTSLQHIKTVTEQVRQSPENAASPQATNSTQVSQPSGAMTRSQESVFMGPQEPSCDSGILRMMSRRDVRAELFLWSFLLWSDTIEMVRVAGHPNVYKSSWLYPVYIFSFISLLRITFTPQNPLLNSLSVLLQDLPFVFVRLGLIIALGTITPVLGLCKNILVTLSYIYFNYLTRIRIFSAFEMSPF", "length": 351 }, "evidence": [ { "id": "RGD:1590637", "url": "https://alliancegenome.org/gene/RGD:1590637#orthology", "database": "AGR" }, { "id": "MGI:1919309", "url": "https://alliancegenome.org/gene/MGI:1919309#orthology", "database": "AGR" }, { "id": "HGNC:23473", "url": "https://alliancegenome.org/gene/HGNC:23473#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-455", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-455#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A5WVU6", "url": "https://www.uniprot.org/uniprotkb/A5WVU6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5PF24-1", "uniprot_ac": "A5PF24", "uniprot_id": "A5PF24_DANRE", "mass": { "chemical_mass": 105607.0, "monoisotopic_mass": 105607.0 }, "refseq": {}, "gene_names": [ { "name": "nlrc6", "type": "recommended", "evidence": [ { "id": "A5PF24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PF24" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "A5PF24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PF24/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PF24", "url": "https://www.uniprot.org/uniprotkb/A5PF24" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nlrc6", "url": "https://www.uniprot.org/uniprotkb/A5PF24", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060421-8264", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060421-8264", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000091320", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000091320", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "678565", "url": "https://www.ncbi.nlm.nih.gov/gene/678565", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:678565", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:678565", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QCKHFAT", "url": "https://omabrowser.org/oma/group/QCKHFAT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5PF24", "url": "https://www.orthodb.org/?gene=A5PF24", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005160238", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005160238", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TVJ7", "url": "https://www.uniprot.org/uniprotkb/A0AB32TVJ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TVJ7-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TVJ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58FZ28", "url": "https://www.uniprot.org/uniprotkb/A0AC58FZ28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58FZ28-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58FZ28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PF24", "url": "https://www.uniprot.org/uniprotkb/A5PF24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PF24-1", "url": "https://www.uniprot.org/uniprotkb/A5PF24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060421-8264", "url": "https://zfin.org/ZDB-GENE-060421-8264", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MQKSKSPESSVASVTSDQSTDPPQNYRGHTELTFSHDHLHAEVHKTFRSNLLTKFQCVSEGTATDKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLMNLIAGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEEMMRGSRKGEIPKTLTEMYTHFLIIQTCIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENRRSKYAHWFKRQTISDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQRLLNNHLTQVGNISYSQEKTVEYIKTQIKMNPSPEKSINLFLCLNELGDHSLVNEVQEYVRSGDLSGSRFSSSQWSAVVFILLTLEQLDEFNLRRYVIGYGHQTQTQKFQTPDKVLQKLLPVVEASRSAVLFDCGISDKGCAALASALRSNSSNLRELDLSYNIVGDSGVKLLSAGLKDPHCKLEKLRLRCCGVSDEGCADLASVLRSNSSNLRELELSKNINVGDSGVKLLSAGLKDPHCKLEKLRLGYCGVSDEGCAALASVLRSNSSNLRELDLSDNKIVDSGVKRLSAGLKDPQCKLETLRLINCDVSGKGCAALASALRSNSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLTLNYCGVSDASCADLASALRSNSSNLRELNLKWNRVEGIGVKWLSDLRDDPHYKLETLHISWGFIC", "length": 938, "header": "tr|A5PF24-1|A5PF24_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=nlrc6 PE=4 SV=1 CANONICAL=A5PF24-1" }, "isoforms": [ { "isoform_ac": "A0AB32TVJ7-1", "url": "https://www.uniprot.org/uniprotkb/A5PF24/entry#A0AB32TVJ7-1", "sequence": { "sequence": "MQKSKSPESSVASVTSDQSTDPPQNYRGHTELTFSHDHLHAEVHKTFRSNLLTKFQCVSEGTATDKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLMNLIAGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEEMMRGSRKGEIPKTLTEMYTHFLIIQTCIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENRRSKYAHWFKRQTISDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQRLLNNHLTQVGNISYSQEKTVEYIKTQIKMNPSPEKSINLFLCLNELGDHSLVNEVQEYVRSGDLSGSRFSSSQWSAVVFILLTLEQLDEFNLRRYVIGYGHQTQTQKFQTPDKVLQKLLPVVEASRSAVLFDCGISDKGCAALASALRSNSSNLRELDLSYNIVGDSGVKLLSAGLKDPHCKLEKLRLRCCGVSDEGCADLASVLRSNSSNLRELELSKNINVGDSGVKLLSAGLKDPHCKLEKLRLINCDVSGKGCAALASALRSNSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLTLNYCGVSDASCADLASALRSNSSNLRELNLKWNRVEGIGVKWLSDLRDDPHYKLETLHISWGFIC", "length": 880, "header": "tr|A0AB32TVJ7-1|A5PF24_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=nlrc6 PE=4 SV=1 CANONICAL=A5PF24-1" }, "locus": {} }, { "isoform_ac": "A0AC58FZ28-1", "url": "https://www.uniprot.org/uniprotkb/A5PF24/entry#A0AC58FZ28-1", "sequence": { "sequence": "MQKSKSPESSVASVTSDQSTDPPQNYRGHTELTFSHDHLHAEVHKTFRSNLLTKFQCVSEGTATDKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLMNLIAGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEEMMRGSRKGEIPKTLTEMYTHFLIIQTCIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENRRSKYAHWFKRQTISDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQRLLNNHLTQVGNISYSQEKTVEYIKTQIKMNPSPEKSINLFLCLNELGDHSLVNEVQEYVRSGDLSGSRFSSSQWSAVVFILLTLEQLDEFNLRRYVIGYGHQTQTQKFQTPDKVLQKLLPVVEASRSAVLFDCGISDKGCAALASALRSNSSNLRELDLSYNIVGDSGVKLLSAGLKDPHCKLEKLRLRCCGVSDEGCADLASVLRSNSSNLRELELSKNINVGDSGVKLLSAGLKDPHCKLEKLRLGYCGVSDEGCAALASVLRSNSSNLRELDLSDNKIVDSGVKRLSAGLKDPQCKLETLRLINCDVSGKGCAALASALRSNSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLTISWGFIC", "length": 880, "header": "tr|A0AC58FZ28-1|A0AC58FZ28_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X3 OS=Danio rerio OX=7955 GN=nlrc6 PE=4 SV=1 CANONICAL=A5PF24-1" }, "locus": {} }, { "isoform_ac": "A5PF24-1", "url": "https://www.uniprot.org/uniprotkb/A5PF24/entry#A5PF24-1", "sequence": { "sequence": "MQKSKSPESSVASVTSDQSTDPPQNYRGHTELTFSHDHLHAEVHKTFRSNLLTKFQCVSEGTATDKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLMNLIAGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEEMMRGSRKGEIPKTLTEMYTHFLIIQTCIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENRRSKYAHWFKRQTISDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQRLLNNHLTQVGNISYSQEKTVEYIKTQIKMNPSPEKSINLFLCLNELGDHSLVNEVQEYVRSGDLSGSRFSSSQWSAVVFILLTLEQLDEFNLRRYVIGYGHQTQTQKFQTPDKVLQKLLPVVEASRSAVLFDCGISDKGCAALASALRSNSSNLRELDLSYNIVGDSGVKLLSAGLKDPHCKLEKLRLRCCGVSDEGCADLASVLRSNSSNLRELELSKNINVGDSGVKLLSAGLKDPHCKLEKLRLGYCGVSDEGCAALASVLRSNSSNLRELDLSDNKIVDSGVKRLSAGLKDPQCKLETLRLINCDVSGKGCAALASALRSNSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLTLNYCGVSDASCADLASALRSNSSNLRELNLKWNRVEGIGVKWLSDLRDDPHYKLETLHISWGFIC", "length": 938, "header": "tr|A5PF24-1|A5PF24_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=nlrc6 PE=4 SV=1 CANONICAL=A5PF24-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:678565", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:678565", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A5PF24", "url": "https://www.uniprot.org/uniprotkb/A5PF24" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5PF24", "url": "https://www.uniprot.org/uniprotkb/A5PF24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 661, "end_pos": 663, "annotation": "n_glycosylation_sequon" }, { "start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" }, { "start_pos": 778, "end_pos": 780, "annotation": "n_glycosylation_sequon" }, { "start_pos": 836, "end_pos": 838, "annotation": "n_glycosylation_sequon" }, { "start_pos": 844, "end_pos": 846, "annotation": "n_glycosylation_sequon" }, { "start_pos": 894, "end_pos": 896, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5PF24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PF24" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 128, "end_pos": 261, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 522, "end_pos": 524 }, { "start_pos": 661, "end_pos": 663 }, { "start_pos": 719, "end_pos": 721 }, { "start_pos": 778, "end_pos": 780 }, { "start_pos": 836, "end_pos": 838 }, { "start_pos": 844, "end_pos": 846 }, { "start_pos": 894, "end_pos": 896 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A5PMS4-1", "uniprot_ac": "A5PMS4", "uniprot_id": "A5PMS4_DANRE", "mass": { "chemical_mass": 38656.0, "monoisotopic_mass": 38656.0 }, "refseq": { "ac": "NP_001121831", "name": "rhomboid domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121831" }, "gene_names": [ { "name": "rhbdd3", "type": "recommended", "evidence": [ { "id": "A5PMS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMS4" } ] }, { "name": "rhbdd3", "type": "synonym", "evidence": [ { "id": "NP_001121831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121831" } ] }, { "name": "si:ch211-149d1.4", "type": "synonym", "evidence": [ { "id": "NP_001121831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121831" }, { "id": "A5PMS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMS4" } ] } ], "protein_names": [ { "name": "Rhomboid domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "A5PMS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMS4/entry#names_and_taxonomy" } ] }, { "name": "rhomboid domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "NP_001121831", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121831" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01011292.1, GDQQ01015001.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505389 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jul 31, 2008 this sequence version replaced XP_001337788.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001121831", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121831" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMS4", "url": "https://www.uniprot.org/uniprotkb/A5PMS4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rhbdd3", "url": "https://www.uniprot.org/uniprotkb/A5PMS4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-39", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000079816", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000079816", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14289", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14289", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "797317", "url": "https://www.ncbi.nlm.nih.gov/gene/797317", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022764", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022764", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035952", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035952", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:797317", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797317", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CIGHNYH", "url": "https://omabrowser.org/oma/group/CIGHNYH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5PMS4", "url": "https://www.orthodb.org/?gene=A5PMS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF01694", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01694", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001121831", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121831", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TVS5", "url": "https://www.uniprot.org/uniprotkb/A0AB32TVS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TVS5-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TVS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PMS4", "url": "https://www.uniprot.org/uniprotkb/A5PMS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PMS4-1", "url": "https://www.uniprot.org/uniprotkb/A5PMS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-39", "url": "https://zfin.org/ZDB-GENE-070705-39", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLNNIFPAWMWSGSNRPGCCSGTFLILSLIVSTWLCGIHASLSLGPGGEFPGFYDFIFYAFSNEELTSFLHNISLLLWIGPCQERRWGTFTFLTLSFISALLLPPIYALFLFVTGDEASRVSGYAAIHLALLTAQCRQVKQRRVLRFVPVWFLPWLLLIFDLFLLPSAPGLLHFYAICLGLNYNNELIEMLEQIERLGACACLPKWAYIPVTSRSQLPVYNNTSTRPEPFSSAFQSENYSTWQQSVSEWPQESPLATDSQLLEEQMLRAGILASLHDAPEGTADKVEVPKSSVSSLRLQQLEKMGFPTEKAVVALAATGQLDGAISLLIDDQIGEETVVISKGKKSAS", "length": 348, "header": "tr|A5PMS4-1|A5PMS4_DANRE Isoform 1 of Rhomboid domain-containing protein 3 OS=Danio rerio OX=7955 GN=rhbdd3 PE=4 SV=1 CANONICAL=A5PMS4-1" }, "isoforms": [ { "isoform_ac": "A0AB32TVS5-1", "url": "https://www.uniprot.org/uniprotkb/A5PMS4/entry#A0AB32TVS5-1", "sequence": { "sequence": "MLNNIFPAWMWSGSNRPGCCSGTFLILSLIVSTWLCGIHASLSLGPDFIFYAFSNEELTSFLHNISLLLWIGPCQERRWGTFTFLTLSFISALLLPPIYALFLFVTGDEASRVSGYAAIHLALLTAQCRQVKQRRVLRFVPVWFLPWLLLIFDLFLLPSAPGLLHFYAICLGLNYNNELIEMLEQIERLGACACLPKWAYIPVTSRSQLPVYNNTSTRPEPFSSAFQSENYSTWQQSVSEWPQESPLATDSQLLEEQMLRAGILASLHDAPEGTADKVEVPKSSVSSLRLQQLEKMGFPTEKAVVALAATGQLDGAISLLIDDQIGEETVVISKGKKSAS", "length": 340, "header": "tr|A0AB32TVS5-1|A5PMS4_DANRE Computationally mapped isoform of Rhomboid domain-containing protein 3 OS=Danio rerio OX=7955 GN=rhbdd3 PE=4 SV=1 CANONICAL=A5PMS4-1" }, "locus": {} }, { "isoform_ac": "A5PMS4-1", "url": "https://www.uniprot.org/uniprotkb/A5PMS4/entry#A5PMS4-1", "sequence": { "sequence": "MLNNIFPAWMWSGSNRPGCCSGTFLILSLIVSTWLCGIHASLSLGPGGEFPGFYDFIFYAFSNEELTSFLHNISLLLWIGPCQERRWGTFTFLTLSFISALLLPPIYALFLFVTGDEASRVSGYAAIHLALLTAQCRQVKQRRVLRFVPVWFLPWLLLIFDLFLLPSAPGLLHFYAICLGLNYNNELIEMLEQIERLGACACLPKWAYIPVTSRSQLPVYNNTSTRPEPFSSAFQSENYSTWQQSVSEWPQESPLATDSQLLEEQMLRAGILASLHDAPEGTADKVEVPKSSVSSLRLQQLEKMGFPTEKAVVALAATGQLDGAISLLIDDQIGEETVVISKGKKSAS", "length": 348, "header": "tr|A5PMS4-1|A5PMS4_DANRE Isoform 1 of Rhomboid domain-containing protein 3 OS=Danio rerio OX=7955 GN=rhbdd3 PE=4 SV=1 CANONICAL=A5PMS4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A5PMS4", "url": "https://www.uniprot.org/uniprotkb/A5PMS4" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Rapid identification and isolation of zebrafish cDNA clones.", "journal": "Gene", "date": "1997", "authors": "Gong Z, Yan T, Liao J, Lee S E, He J, Hew C L", "evidence": [ { "database": "UniProtKB", "id": "A5PMS4", "url": "https://www.uniprot.org/uniprotkb/A5PMS4" } ], "reference": [ { "type": "PubMed", "id": "9409775", "url": "https://glygen.org/publication/PubMed/9409775" } ] } ], "pathway": [ { "id": "dre:797317", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797317", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q642B3-1", "protein_name": "Rhomboid domain-containing protein 3", "gene_name": "Rhbdd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHAWDPPASLSRALPLASSVLMLLLSCLWLLGAGPSLRLAPELLTEPWQVHRLLTHALGHTALPGLLLSLLLLPTLGWWQECHLGTLRFLHNSAVLALATGLLAVLLAGLGLSSAAGGCGYMPVHLAMLAGQSYYPGWPQRTLPPWLLPWLLLALTLLLSSEPPFLQLLCGLLAGLAYAAGAFRWLELSERRLQVLQEGVLCRTLAGCWPLKLLPTPGSLGELPVTYPAGVRPATPRPPYLASSSSWPHTDGFAQLPPGLGPGQLTWKNSERDLDWAGPSFASATPMWAALDEQMLQEGIQASLLDVSVQGSQNTLWSPKPSVSSLRLQQLQHMGFPTEQAAVALAATGRVEGAVSLLVEGLVDTEALVTEERSGPAHCKDTGVS", "length": 385 }, "evidence": [ { "id": "MGI:2444684", "url": "https://alliancegenome.org/gene/MGI:2444684#orthology", "database": "AGR" }, { "id": "HGNC:1308", "url": "https://alliancegenome.org/gene/HGNC:1308#orthology", "database": "AGR" }, { "id": "A5PMS4", "url": "https://omabrowser.org/oma/group/A5PMS4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BP97-1", "protein_name": "Rhomboid domain-containing protein 3", "gene_name": "Rhbdd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHAWEAPGSLSRALPLASSVLMLLLSCLWLLGAGPSLRLAPELLMEPWQVHRLLTHALGHTALPGLLLSLLLLPTLGWWQECHLGTVRFLHNSTVLALATGLLAVLLAGLGVSGAAGGCGYMPVHLAMLAGQSHHPGWPQRTLPPWLLPWLLLALTLLLSSEPPFLQLLCGLLTGLAYAAGAFQWLELSEQRLQVLQEGVLCKSLARCWPLRLFPTPGSLGELPVTYPAGVRPATPRPPYLASSDSWPHSDGSAQLPPRLGPGQLTWKNSERGLDWAGSSFASATTMWAALDEQMLQEGIQASLLDVSVQGSQSSLWLPKPSVSSLRLQQLQHMGFPTEQAAVALAATGRVEGAVSLLVEGLVDTEALVTEGRSSPAHCTGTGAS", "length": 385 }, "evidence": [ { "id": "MGI:2444684", "url": "https://alliancegenome.org/gene/MGI:2444684#orthology", "database": "AGR" }, { "id": "HGNC:1308", "url": "https://alliancegenome.org/gene/HGNC:1308#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-39#orthology", "database": "AGR" }, { "id": "A5PMS4", "url": "https://omabrowser.org/oma/group/A5PMS4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3P4-1", "protein_name": "Rhomboid domain-containing protein 3", "gene_name": "RHBDD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHARGPHGQLSPALPLASSVLMLLMSTLWLVGAGPGLVLAPELLLDPWQVHRLLTHALGHTALPGLLLSLLLLPTVGWQQECHLGTLRFLHASALLALASGLLAVLLAGLGLSSAAGSCGYMPVHLAMLAGEGHRPRRPRGALPPWLSPWLLLALTPLLSSEPPFLQLLCGLLAGLAYAAGAFRWLEPSERRLQVLQEGVLCRTLAGCWPLRLLATPGSLAELPVTHPAGVRPPIPGPPYVASPDLWSHWEDSALPPPSLRPVQPTWEGSSEAGLDWAGASFSPGTPMWAALDEQMLQEGIQASLLDGPAQEPQSAPWLSKSSVSSLRLQQLERMGFPTEQAVVALAATGRVEGAVSLLVGGQVGTETLVTHGKGGPAHSEGPGPP", "length": 386 }, "evidence": [ { "id": "MGI:2444684", "url": "https://alliancegenome.org/gene/MGI:2444684#orthology", "database": "AGR" }, { "id": "HGNC:1308", "url": "https://alliancegenome.org/gene/HGNC:1308#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-39#orthology", "database": "AGR" }, { "id": "A5PMS4", "url": "https://omabrowser.org/oma/group/A5PMS4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A5PMS4", "url": "https://www.uniprot.org/uniprotkb/A5PMS4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A5PMS4", "url": "https://www.uniprot.org/uniprotkb/A5PMS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5PMS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMS4" }, { "id": "PF01694", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01694" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S54 rhomboid", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 167, "start_aa": "Phe", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 221, "end_pos": 223 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PJP7-1", "uniprot_ac": "A0A8M9PJP7", "uniprot_id": "A0A8M9PJP7_DANRE", "mass": { "chemical_mass": 42328.0, "monoisotopic_mass": 42328.0 }, "refseq": { "ac": "XP_021331687", "name": "nocturnin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331687" }, "gene_names": [ { "name": "noctb", "type": "recommended", "evidence": [ { "id": "A0A8M9PJP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7" } ] }, { "name": "noctb", "type": "synonym", "evidence": [ { "id": "XP_021331687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331687" } ] } ], "protein_names": [ { "name": "Nocturnin", "type": "recommended", "evidence": [ { "id": "A0A8M9PJP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7/entry#names_and_taxonomy" } ] }, { "name": "Carbon catabolite repression 4-like protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PJP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7/entry#names_and_taxonomy" } ] }, { "name": "nocturnin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021331687", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331687" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021331687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331687" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJP7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "noctb", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110930-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110930-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd09096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "568973", "url": "https://www.ncbi.nlm.nih.gov/gene/568973", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005135", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005135", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036691", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036691", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050410", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050410", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:568973", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568973", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PJP7", "url": "https://www.orthodb.org/?gene=A0A8M9PJP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9Q2W9", "url": "https://www.orthodb.org/?gene=A0A8M9Q2W9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12121", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12121", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12121:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12121:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021331687", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331687", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PJP7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q2W9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2W9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q2W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2W9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110930-4", "url": "https://zfin.org/ZDB-GENE-110930-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEVVACSMGSGSSSLYSALAKSISRSPLPHSCGSTYSPGDNLNLDQDPADPLELLQECREALRERPAHLKRAFVQTGHGDARRTIRVMQWNVLAQALGEGMDNFVQCPLDALNWPERKYMILEEILTYKPDILCLQEVDHYFDMFQPVLATLGYQSSFCPKPWSPCLDVENNNGPDGCALFFNHKRFQLVNTTHLRLSAMMLKTNQVAIVAALRCRSTGRVFCVGVTHLKARSGWEVLRSAQGSDLLRNLRNITQKIETEENAESAIPLIVCGDFNAEPSEDVYRNFATSSLGLDSAYKLLSTDGKTEPPYTTWKIRPSGESCHTLDYVWYSHRAFDVNAVLDFPTAEQIGPNRLPSYNYPSDHLSLVCDFCFTDPVN", "length": 378, "header": "tr|A0A8M9PJP7-1|A0A8M9PJP7_DANRE Isoform 1 of Nocturnin OS=Danio rerio OX=7955 GN=noctb PE=3 SV=1 CANONICAL=A0A8M9PJP7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PJP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7/entry#A0A8M9PJP7-1", "sequence": { "sequence": "MEVVACSMGSGSSSLYSALAKSISRSPLPHSCGSTYSPGDNLNLDQDPADPLELLQECREALRERPAHLKRAFVQTGHGDARRTIRVMQWNVLAQALGEGMDNFVQCPLDALNWPERKYMILEEILTYKPDILCLQEVDHYFDMFQPVLATLGYQSSFCPKPWSPCLDVENNNGPDGCALFFNHKRFQLVNTTHLRLSAMMLKTNQVAIVAALRCRSTGRVFCVGVTHLKARSGWEVLRSAQGSDLLRNLRNITQKIETEENAESAIPLIVCGDFNAEPSEDVYRNFATSSLGLDSAYKLLSTDGKTEPPYTTWKIRPSGESCHTLDYVWYSHRAFDVNAVLDFPTAEQIGPNRLPSYNYPSDHLSLVCDFCFTDPVN", "length": 378, "header": "tr|A0A8M9PJP7-1|A0A8M9PJP7_DANRE Isoform 1 of Nocturnin OS=Danio rerio OX=7955 GN=noctb PE=3 SV=1 CANONICAL=A0A8M9PJP7-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q2W9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7/entry#A0A8M9Q2W9-1", "sequence": { "sequence": "MGSGSSSLYSALAKSISRSPLPHSCGSTYSPGDNLNLDQDPADPLELLQECREALRERPAHLKRAFVQTGHGDARRTIRVMQWNVLAQALGEGMDNFVQCPLDALNWPERKYMILEEILTYKPDILCLQEVDHYFDMFQPVLATLGYQSSFCPKPWSPCLDVENNNGPDGCALFFNHKRFQLVNTTHLRLSAMMLKTNQVAIVAALRCRSTGRVFCVGVTHLKARSGWEVLRSAQGSDLLRNLRNITQKIETEENAESAIPLIVCGDFNAEPSEDVYRNFATSSLGLDSAYKLLSTDGKTEPPYTTWKIRPSGESCHTLDYVWYSHRAFDVNAVLDFPTAEQIGPNRLPSYNYPSDHLSLVCDFCFTDPVN", "length": 371, "header": "tr|A0A8M9Q2W9-1|A0A8M9PJP7_DANRE Computationally mapped isoform of Nocturnin OS=Danio rerio OX=7955 GN=noctb PE=3 SV=1 CANONICAL=A0A8M9PJP7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:568973", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568973", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A8JQX3-1", "protein_name": "Nocturnin", "gene_name": "cu", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDQKTTGLRENYGHRRQPALGKAMPVTALLLNLESNPLDYSRNDIGAELLEDDDKPPQLFSVTDEPPSPNEEDYKPPNHHEDDGKLAGERHREIPCSNCLKTAPGHLIDRQSAINEMCQRLCGPECRRPQGLTLDGVRQDFLRQYEIAEAVAKTSAMTSTVQMKQRLAARKLEFEKEMEMDEQLGVASPRNDINLGQSSTVAATGMGEFEFEPPRDLLLYLVRMGSFNSAPKINNVDSQDDGLVLPSGLSTPALLQHVQQLRGGGIEQPSLLTRGFLKPLLADEDVADGLRCLKLNSVSRVCSAPVEGDDIRLLQWNILSQTLGQHNDGFVRCPEEALTWEHRKYLIVQEILQNQPDVICLQEVDHFKFLQTVLGSQNYAGIFFPKPDSPCLYIEQNNGPDGCAIFYKRDKLQLQGYDTRILEVWRVQSNQVAIAARLRMRSSGREFCVATTHLKARHGALLAKLRNEQGRDLIRFVKQFAGDTPLLLCGDFNAEPVEPIYATILGCDLLRLGSAYADVKLDREEILHPNADVGEFVAKSMKREPPYTTWKIREEGEECHTIDYVFYTPDRLKIKNCLDFPAGEQIGKNRTPSFQYPSDHFSLVCDFELLPPTENGKESGSGSGSDGENETEVEGSKHGSIQ", "length": 642 }, "evidence": [ { "id": "FB:FBgn0261808", "url": "https://alliancegenome.org/gene/FB:FBgn0261808#orthology", "database": "AGR" }, { "id": "RGD:1587344", "url": "https://alliancegenome.org/gene/RGD:1587344#orthology", "database": "AGR" }, { "id": "HGNC:14254", "url": "https://alliancegenome.org/gene/HGNC:14254#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110930-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110930-4#orthology", "database": "AGR" }, { "id": "MGI:109382", "url": "https://alliancegenome.org/gene/MGI:109382#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "E7F177-1", "protein_name": "Nocturnin", "gene_name": "nocta", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYPARRCSSLFHRDLAAVCLSSLGTHPKKSAQPKKNSLQSSRHRSNSSPLLLRRLQVCQMGSNSSSRLFSTLAQTLSSAALTDPHVDADDYEYEQADPDVLLRECGEVLRNRPPRLHREFIMTRACSLQNSPLRIMQWNILAQALGEGKDGFVRCPMEALNWSERKYLILEEILTYRPDVVCLQEVDHYFDTFQPVLSSLGYQSSFCPKPCSPCLDVHNNNGPDGCALFFNRRRFQMLHTAHLRLSAMMLKTNQVAVVATLRCKLTGRVFCVAVTHLKARSGWEAFRSAQGANLLQQLHEITSQSNPEMHQDDQTEGIPLIVCGDFNAEPNEEVYRHFRSSSLGLDSVYKCLSDDRTTEPPYTSWKIRPSGECCSTLDYIWYSEKAFEVDAVLRIPSEEQIGPDRLPSFHYPSDHLSLVCDLSFSQQPHRLM", "length": 432 }, "evidence": [ { "id": "HGNC:14254", "url": "https://alliancegenome.org/gene/HGNC:14254#orthology", "database": "AGR" }, { "id": "MGI:109382", "url": "https://alliancegenome.org/gene/MGI:109382#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O35710-1", "protein_name": "Nocturnin", "gene_name": "Noct", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYQSPRRLCSALLLRDAPGLRRTLVPGPRRTLAPPVLGSRPKSPQLQAAAASGAARSRPRTVSSMGNGTSRLYSALAKTVNSSAAAQHPEYLVSTDPEHLEPIDPKELLEECRAVLHTRPPRYQRDFVDLRTDCSSSHSPIRVMQWNILAQALGEGKDNFVQCPVEALKWEERKCLILEEILAYQPDILCLQEVDHYFDTFQPLLSRLGYQGTFFPKPWSPCLDVEHNNGPDGCALFFLQNRFKLISSTNIRLTAMTLKTNQVAIAQTLECKESGRQFCIAVTHLKARTGWERFRSAQGCDLLQNLQNITQGAKIPLIVCGDFNAEPTEEVYKHFASSSLNLNSAYKLLSPDGQSEPPYTTWKIRTSGECRHTLDYIWYSRHALSVTSALDLLTEEQIGPNRLPSFHYPSDHLSLVCDFSFNEEPHELF", "length": 429 }, "evidence": [ { "id": "FB:FBgn0261808", "url": "https://alliancegenome.org/gene/FB:FBgn0261808#orthology", "database": "AGR" }, { "id": "RGD:1587344", "url": "https://alliancegenome.org/gene/RGD:1587344#orthology", "database": "AGR" }, { "id": "HGNC:14254", "url": "https://alliancegenome.org/gene/HGNC:14254#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110930-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110930-4#orthology", "database": "AGR" }, { "id": "MGI:109382", "url": "https://alliancegenome.org/gene/MGI:109382#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q03264-1", "protein_name": "RNA exonuclease NGL2", "gene_name": "NGL2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTQDKEVKVVAPDVAPDQEVEINKSVKDAKHQTNDDSLLQHKKKGKKGKKSKPIVTPEHIAKVRAEREVMRKAKRDAMLAQGVDPDCPPELHFIRRPFLSLHEAEPVTGFRFKLMTYNCLAQALIRRKLFPDSGDALKWYRRSKVLLNEFKYYNSDVICLQEIDHIQFQSFWKDEFSKLGYDGQYYRNATKNHGVAIMWRRELFHQVDKMLIDYDKESSESISTRTTTNNVGLVLALKFSEKVLSNLGKKSSKKCGILIGTTHLFWHPFGTYERTRQCYIVLKKMKEFMHRVNVLQNENDGDLSHWFPFFCGDFNSQPFDTPYLSMTSKPVHYRNRAKTVIGCSTSYKFSKVRDGEEGADDEEGGNIEKYGKDQPESPVPEKFHANEEQSELVDKMAQLHNSLDMRAISLYSVGYKNVHPENAGLDNDRGEPEISNWANTWRGLLDYLFYVKKWDPQSNCQEVETLGDFEKENKVKCRGFLRMPPGNEMTKHGQPHVGEYASDHLSMVCDLELQL", "length": 515 }, "evidence": [ { "id": "FB:FBgn0261808", "url": "https://alliancegenome.org/gene/FB:FBgn0261808#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9ET55-1", "protein_name": "Nocturnin", "gene_name": "Noct", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYQSPRRLCSALLLRDAPGLRRTLVPGPRRTLAPPVLGSRPASPQLQAAASGAARSRPRTVSPMGNGTSRLYSALAKTINSSAAAQHPEYLVSADPEHLEPIDPKELLEECRAVLHTRPPRYQRDFVDLRTDCSSSHPPIRVMQWNILAQALGEGKDNFVQCPVEALKWEERKCLILEEILAYQPDILCLQEVDHYFDTFQPLLSRLGYQGTFFPKPWSPCLDVEHNNGPDGCALFFLQSRFKLINSTNIRLTAMTLKTNQVAIAQTLECKESGRQFCIAVTHLKARTGWERFRSAQGCDLLQNLQNITEGAKIPLIVCGDFNAEPTEEVYKHFASSSLNLNSAYKLLSPDGQSEPPYTTWKIRTSGECRHTLDYIWYSRHALSVTSALDLLTEEQIGPNRLPSFHYPSDHLSLVCDFSFNEEPDELL", "length": 428 }, "evidence": [ { "id": "FB:FBgn0261808", "url": "https://alliancegenome.org/gene/FB:FBgn0261808#orthology", "database": "AGR" }, { "id": "RGD:1587344", "url": "https://alliancegenome.org/gene/RGD:1587344#orthology", "database": "AGR" }, { "id": "HGNC:14254", "url": "https://alliancegenome.org/gene/HGNC:14254#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110930-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110930-4#orthology", "database": "AGR" }, { "id": "MGI:109382", "url": "https://alliancegenome.org/gene/MGI:109382#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UK39-1", "protein_name": "Nocturnin", "gene_name": "NOCT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFHSPRRLCSALLQRDAPGLRRLPAPGLRRPLSPPAAVPRPASPRLLAAASAASGAARSCSRTVCSMGTGTSRLYSALAKTLNSSAASQHPEYLVSPDPEHLEPIDPKELLEECRAVLHTRPPRFQRDFVDLRTDCPSTHPPIRVMQWNILAQALGEGKDNFVQCPVEALKWEERKCLILEEILAYQPDILCLQEVDHYFDTFQPLLSRLGYQGTFFPKPWSPCLDVEHNNGPDGCALFFLQNRFKLVNSANIRLTAMTLKTNQVAIAQTLECKESGRQFCIAVTHLKARTGWERFRSAQGCDLLQNLQNITQGAKIPLIVCGDFNAEPTEEVYKHFASSSLNLNSAYKLLSADGQSEPPYTTWKIRTSGECRHTLDYIWYSKHALNVRSALDLLTEEQIGPNRLPSFNYPSDHLSLVCDFSFTEESDGLS", "length": 431 }, "evidence": [ { "id": "FB:FBgn0261808", "url": "https://alliancegenome.org/gene/FB:FBgn0261808#orthology", "database": "AGR" }, { "id": "RGD:1587344", "url": "https://alliancegenome.org/gene/RGD:1587344#orthology", "database": "AGR" }, { "id": "HGNC:14254", "url": "https://alliancegenome.org/gene/HGNC:14254#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110930-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110930-4#orthology", "database": "AGR" }, { "id": "MGI:109382", "url": "https://alliancegenome.org/gene/MGI:109382#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJP7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJP7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7" } ], "pmid": "" }, { "name": "poly(A)-specific ribonuclease activity", "id": "GO:0004535", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004535", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJP7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7" } ], "pmid": "" }, { "name": "3'-5'-RNA exonuclease activity", "id": "GO:0000175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000175", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJP7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "circadian rhythm", "id": "GO:0007623", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007623", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJP7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7" } ], "pmid": "" }, { "name": "nucleobase-containing compound metabolic process", "id": "GO:0006139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006139", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJP7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PJP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP7" }, { "id": "PF03372", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03372" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Endonuclease/exonuclease/phosphatase", "eco_id": "ECO_0000259", "start_pos": 88, "end_pos": 364, "start_aa": "Met", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 252, "end_pos": 254 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A3KP40-1", "uniprot_ac": "A3KP40", "uniprot_id": "CH034_DANRE", "mass": { "chemical_mass": 68794.0, "monoisotopic_mass": 68794.0 }, "refseq": {}, "gene_names": [ { "name": "zgc:162928", "type": "synonym", "evidence": [ { "id": "A3KP40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KP40" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C8orf34 homolog", "type": "recommended", "evidence": [ { "id": "A3KP40", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KP40/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KP40", "url": "https://www.uniprot.org/uniprotkb/A3KP40" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A3KP40", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070410-112", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070410-112", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A3KP40", "url": "https://alphafold.ebi.ac.uk/entry/A3KP40", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22980", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22980", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "557144", "url": "https://www.ncbi.nlm.nih.gov/gene/557144", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040687", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040687", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:557144", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557144", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M2B9L9", "url": "https://www.orthodb.org/?gene=A0A8M2B9L9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A3KP40", "url": "https://www.orthodb.org/?gene=A3KP40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32000", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32000", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32000:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32000:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17824", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17824", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A3KP40", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A3KP40", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0A8M2B9L9", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B9L9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B9L9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B9L9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13ABP3", "url": "https://www.uniprot.org/uniprotkb/A0AB13ABP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13ABP3-1", "url": "https://www.uniprot.org/uniprotkb/A0AB13ABP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KP40", "url": "https://www.uniprot.org/uniprotkb/A3KP40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KP40-1", "url": "https://www.uniprot.org/uniprotkb/A3KP40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070410-112", "url": "https://zfin.org/ZDB-GENE-070410-112", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASLQQSRIQSYLEKNKIGPLFEEMMTKLITETPDHPIPFLIGHLQTKQESPGRIQRTLSGSAALWAEGSSEYKGTRRDSRGYEKPWQIHPKKPKKSKSDLAVSNISPPSPESKSLPRSILRPTWDWRTKPESRGFDELNHILLESKKLGKALENLSRSIAVSDDFDLDPRAYNSVLRPRVVGEWVGREEEDLDPLAAEMFQPPVPRAKTEGWTSKDNSPVGSLKMETKGKGLKQQQQNHKKLLAAMLSQDSFDSMPDSAPSVTEDEMEDEDDAMELLEDLDDLRMEGVTGLLQSGSKFSQGRSSYYTEPQAKVTLNICSRCARLQGDSLTARTEEEPERHVPEQAVPEVPCPLPTVTETLTATEDLQTASQVTGLRHPVWASDVKPIRGTSPQTARRALQLQDSLFSKELENMGKHLAEVEKDLAKLAEQGKLNRSPNSPHRSLLLPPLFHTTNTLPVLGQTSRPQSPSSLSSKTTGLPLHNPKPTSLMTDRTSPSNSSSRAQTPSRPITPNSLMMRSFTAAGHGNKERVYGRSRSRPVTPTGQITRPILTPPGLSTTDLYGGLWSTLTEDEFYQQLQAVRKPWRIPSDAESDCLDPPEQDKCEFYTSDPSHSLKTL", "length": 618, "header": "sp|A3KP40-1|CH034_DANRE Isoform 1 of Uncharacterized protein C8orf34 homolog OS=Danio rerio OX=7955 GN= PE=2 SV=1 CANONICAL=A3KP40-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B9L9-1", "url": "https://www.uniprot.org/uniprotkb/A3KP40/entry#A0A8M2B9L9-1", "sequence": { "sequence": "MQHILMASLQQSRIQSYLEKNKIGPLFEEMMTKLITETPDHPIPFLIGHLQTKQESPGRIQRTLSGSAALWAESSSEYKGTRRDSRGYEKPWQIHPKKPKKSKSDLAVSNISPPSPESKSLPRSILRPTWDWRTKPESRDFDELNHILLESKKLGKALENLSRSIAVSDDFDLDPRAYNSVLRPRVVGEWVGREEEDLDPLAAEMFQPPVPRAKTEGWTSKDNSPVGSLKMETKGKGLKQQQQNHKKLLAAMLSQDSFDSMPDSAPSVTEDEIEDEDDAMELLEDLDDLRMEGVTGLLQSGSKFSQGRSSYYTEPQAKVTLNICSRLQGDSLTARTEEEPERHVPEQAVPEVPCPLPAVTETLTATEDLQTASQVTGLRHPVWASDVKPIRGTSPQTARRALQLQDSLFSKELENMGKHLAEVEKDLAKLAEQGKLNRSPNSPHRSLLLPPLFHTTNTLPVLGQTSRPQSPSSLSSKTTGLPLHNPKPTSLMTDRTSPSNSSSRAQTPSRPITPNSLMMRSFTAAGHGNKERVYGRSRSRPVTPTGQITRPILTPPGLSTTDLYGGLWSTLTEDEFYQQLQAVRKPWRIPSDAESDCLDPPEQDKCNPSGVRDASKRSVFSGL", "length": 623, "header": "tr|A0A8M2B9L9-1|CH034_DANRE Computationally mapped isoform of Uncharacterized protein C8orf34 homolog OS=Danio rerio OX=7955 GN= PE=2 SV=1 CANONICAL=A3KP40-1" }, "locus": {} }, { "isoform_ac": "A0AB13ABP3-1", "url": "https://www.uniprot.org/uniprotkb/A3KP40/entry#A0AB13ABP3-1", "sequence": { "sequence": "MASLQQSRIQSYLEKNKIGPLFEEMMTKLITETPDHPIPFLIGHLQTKQESPGRIQRTLSGSAALWAESSSEYKGTRRDSRGYEKPWQIHPKKPKKSKSDLAVSNISPPSPESKSLPRSILRPTWDWRTKPESRDFDELNHILLESKKLGKALENLSRSIAVSDDFDLDPRAYNSVLRPRVVGEWVGREEEDLDPLAAEMFQPPVPRAKTEGWTSKDNSPVGSLKMETKGKGLKQQQQNHKKLLAAMLSQDSFDSMPDSAPSVTEDEIEDEDDAMELLEDLDDLRMEGVTGLLQSGSKFSQGRSSYYTEPQAKVTLNICSRCARLQGDSLTARTEEEPERHVPEQAVPEVPCPLPAVTETLTATEDLQTASQVTGLRHPVWASDVKPIRGTSPQTARRALQLQDSLFSKELENMGKHLAEVEKDLAKLAEQGKLNRSPNSPHRSLLLPPLFHTTNTLPVLGQTSRPQSPSSLSSKTTGLPLHNPKPTSLMTDRTSPSNSSSRAQTPSRPITPNSLMMRSFTAAGHGNKERVYGRSRSRPVTPTGQITRPILTPPGLSTTDLYGGLWSTLTEDEFYQQLQAVRKPWRIPSDAESDCLDPPEQDKCNPSGVRDASKRSVFSGL", "length": 621, "header": "tr|A0AB13ABP3-1|CH034_DANRE Computationally mapped isoform of Uncharacterized protein C8orf34 homolog OS=Danio rerio OX=7955 GN= PE=2 SV=1 CANONICAL=A3KP40-1" }, "locus": {} }, { "isoform_ac": "A3KP40-1", "url": "https://www.uniprot.org/uniprotkb/A3KP40/entry#A3KP40-1", "sequence": { "sequence": "MASLQQSRIQSYLEKNKIGPLFEEMMTKLITETPDHPIPFLIGHLQTKQESPGRIQRTLSGSAALWAEGSSEYKGTRRDSRGYEKPWQIHPKKPKKSKSDLAVSNISPPSPESKSLPRSILRPTWDWRTKPESRGFDELNHILLESKKLGKALENLSRSIAVSDDFDLDPRAYNSVLRPRVVGEWVGREEEDLDPLAAEMFQPPVPRAKTEGWTSKDNSPVGSLKMETKGKGLKQQQQNHKKLLAAMLSQDSFDSMPDSAPSVTEDEMEDEDDAMELLEDLDDLRMEGVTGLLQSGSKFSQGRSSYYTEPQAKVTLNICSRCARLQGDSLTARTEEEPERHVPEQAVPEVPCPLPTVTETLTATEDLQTASQVTGLRHPVWASDVKPIRGTSPQTARRALQLQDSLFSKELENMGKHLAEVEKDLAKLAEQGKLNRSPNSPHRSLLLPPLFHTTNTLPVLGQTSRPQSPSSLSSKTTGLPLHNPKPTSLMTDRTSPSNSSSRAQTPSRPITPNSLMMRSFTAAGHGNKERVYGRSRSRPVTPTGQITRPILTPPGLSTTDLYGGLWSTLTEDEFYQQLQAVRKPWRIPSDAESDCLDPPEQDKCEFYTSDPSHSLKTL", "length": 618, "header": "sp|A3KP40-1|CH034_DANRE Isoform 1 of Uncharacterized protein C8orf34 homolog OS=Danio rerio OX=7955 GN= PE=2 SV=1 CANONICAL=A3KP40-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0AB13ABP3", "url": "https://www.uniprot.org/uniprotkb/A0AB13ABP3" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "A0AB13ABP3", "url": "https://www.uniprot.org/uniprotkb/A0AB13ABP3" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] } ], "pathway": [ { "id": "dre:557144", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557144", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZPH6-1", "protein_name": "Similar to human chromosome 8 open reading frame 34", "gene_name": "C5h8orf34", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASRQQTRIQAYLEKNKIGPLFEELMTKLITETPDQPIPFLIDHLQSKQGNRGQLQRTLSGSAALWAESESSEPKGTRRDLRSYDKPWQMNAKKPKKSKSDLAVSNISPPSPDSKSLPRSVDHPKWTWRTKPQSRDFDELNHILQESKKLGKALEKLSRSIATSDELDKETVAFNSSLLRPRVIGEWIGRAENDADPLAAEMLQPPVPRSKNDSWESEDSSSSPAGSLKMEPKTKGLKQQQQQHKKLLAAMLSQDSFESIHSPTPSVIEEDIDNEDDAMELLEDLDDLRMEGVTSLVLSGSKFNQGRPAHPAEPQAKVTLNICSRCARLQGDNMMERTEDTLQVFPSPDEIIPDSLDSLPGTEETLMEEGEDFEKTSNLTEPGEASSGGYSLKSYMEEDESLKQLQVVHQPWLLPSDTESDGIEAEQDKRSADLLCVPCSSCPTLVYSGLSVKQAKEFTSGP", "length": 462 }, "evidence": [ { "id": "RGD:1564053", "url": "https://alliancegenome.org/gene/RGD:1564053#orthology", "database": "AGR" }, { "id": "MGI:2444149", "url": "https://alliancegenome.org/gene/MGI:2444149#orthology", "database": "AGR" }, { "id": "HGNC:30905", "url": "https://alliancegenome.org/gene/HGNC:30905#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070410-112", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070410-112#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q49A92-6", "protein_name": "Uncharacterized protein C8orf34", "gene_name": "C8orf34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSPLASELSELAALRPGFRLSAPHARVAPRAATHARGRGRASHAGQPRLRSSCPGPSPGKRRVVPSGGAQPRVLPALSSRSHLFPMASHPQTRIQAYLEKNKIGPLFEELMTKLITETPDQPIPFLIDHLQSKQGNRGQLQRTLSGSAALWAESEKSESKGTRRDFRSYDKPWQLNAKKPKKSKSDLAVSNISPPSPDSKSLPRSVEHPKWNWRTKPQSRDFDELNHILQESKKLGKALENLSRSIAISDELDKETVTFNSSLLRPRVIGEWIGREENDADPLAAEMLQPPIPRSKNDQWESEDSGSSPAGSLKMEPKNKGLKQQQQQHKKLLAAMLSQDSFESIHSPTPSVTEEDIDNEDDAMELLEDLNDLRMEGVTTLVPSGSKFNQGRPTYPAEPQAKVTLNICSRCARLQGDNLEERTEESLPILHSPDEKIPDSFDSLPGTEEALMEEGDEFEKASKLTGPGEASSGVGHSLKNYMEEDESLKQLQVVHQPWILPSDTESEGVEAEQEKRSADLLLCVPCSSCPTLVYSGL", "length": 538 }, "evidence": [ { "id": "RGD:1564053", "url": "https://alliancegenome.org/gene/RGD:1564053#orthology", "database": "AGR" }, { "id": "MGI:2444149", "url": "https://alliancegenome.org/gene/MGI:2444149#orthology", "database": "AGR" }, { "id": "HGNC:30905", "url": "https://alliancegenome.org/gene/HGNC:30905#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070410-112", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070410-112#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BZJ8-1", "protein_name": "Uncharacterized protein C8orf34 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASRQQTRIQAYLEKNKIGPLFEELMTKLITETPDQPIPFLIDHLQSKQGNQGQLQRALSGSAALWAESESSEPKGTRRDFRSYDKPWQMNAKKPKKSKSDLAVSNISPPSPDSKSLPRSVDHLKWNWRTKPQSRDFDELNHILQESKKLGKALENLSRSIAISDELDKETLAFNSSLLRPRVIGEWIGRAENDADPLAAEMLQPPVPRSKNDSWESEDSSSSPAGSLKMEPKTKGLKQQQQQHKKLLAAMLSQDSFESIHSPTPSVIEEDIDNEDDAMELLENLDDLRMEGVTTLVLSGSKFNQGRPTHPAEPQAKVTLNICSRLQGDNLMERTEDTLQILHTPDEIIPDSLDSLPGTEETLMEEGEDFEKTSNLTEPGEASSGAHSLKSYMEEDESLKQLQVVHQPWLLPSDTESEGIEAEQDKRSADLLCVPCSSCPTLIYSGLSVKPAKEVASGP", "length": 459 }, "evidence": [ { "id": "RGD:1564053", "url": "https://alliancegenome.org/gene/RGD:1564053#orthology", "database": "AGR" }, { "id": "MGI:2444149", "url": "https://alliancegenome.org/gene/MGI:2444149#orthology", "database": "AGR" }, { "id": "HGNC:30905", "url": "https://alliancegenome.org/gene/HGNC:30905#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070410-112", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070410-112#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 498, "end_pos": 500, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 498, "end_pos": 500 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2CEB4-1", "uniprot_ac": "A2CEB4", "uniprot_id": "A2CEB4_DANRE", "mass": { "chemical_mass": 168503.0, "monoisotopic_mass": 168503.0 }, "refseq": { "ac": "NP_001122017", "name": "golgin subfamily A member 3 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122017" }, "gene_names": [ { "name": "golga3", "type": "recommended", "evidence": [ { "id": "A2CEB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEB4" } ] }, { "name": "golga3", "type": "synonym", "evidence": [ { "id": "NP_001122017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122017" } ] }, { "name": "si:dkey-215k6.6", "type": "synonym", "evidence": [ { "id": "NP_001122017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122017" }, { "id": "A2CEB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEB4" } ] } ], "protein_names": [ { "name": "Golgin subfamily A member 3", "type": "synonym", "evidence": [ { "id": "A2CEB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEB4/entry#names_and_taxonomy" } ] }, { "name": "golgi autoantigen, golgin subfamily a, 3", "type": "synonym", "evidence": [ { "id": "NP_001122017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122017" } ] }, { "name": "golgin subfamily A member 3 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001122017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122017" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01011728.1, SRR32588718.9957793.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On or before Jul 29, 2025 this sequence version replaced XP_005165138.1, NP_001122017.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001122017", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122017" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CEB4", "url": "https://www.uniprot.org/uniprotkb/A2CEB4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "golga3", "url": "https://www.uniprot.org/uniprotkb/A2CEB4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-252", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-252", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000062511", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000062511", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "570879", "url": "https://www.ncbi.nlm.nih.gov/gene/570879", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR051841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570879", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570879", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDDQHAQ", "url": "https://omabrowser.org/oma/group/QDDQHAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BC82", "url": "https://www.orthodb.org/?gene=A0A8M2BC82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BCD1", "url": "https://www.orthodb.org/?gene=A0A8M2BCD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A2CEB4", "url": "https://www.orthodb.org/?gene=A2CEB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18902", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18902", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18902:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18902:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "R-DRE-9696270", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9696270", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001122017", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001122017", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BC82", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BC82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BC82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BC82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BCD1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BCD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BCD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BCD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2CEB4", "url": "https://www.uniprot.org/uniprotkb/A2CEB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2CEB4-1", "url": "https://www.uniprot.org/uniprotkb/A2CEB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-252", "url": "https://zfin.org/ZDB-GENE-060526-252", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MENGNNGMVSIEAKPPQHPDAQHCKNPNSNTVESLKPERSLVTEKIPNGHVKAELLPNGEAMVEGQDVGGGSTPPSATPSPGSRLSDSSPSTELDPGVVSFPDSLERSEGSVHTGDALQSLRLSIPMQETELSSTDPCVEMENEEKIRQEARRRLEEQLKQYRAQRHTERTRRSTPKSRPFSTLDPELMLHPEGLPRANTVAMTKEYSFLRTSVPRGPKLGSLGIPSSREKKSKSSRSSKIHSLADYKTPESEGSGGAVSASADSSFTSLHSTISSVSTVSEISISSEANNHSESSQLIRDNISEVDGSESGFRADGNDSDSSSYSSVSTTGTYNMLSAIVNRPKAPYTVEGREIAAEAMGHFPSLQEVLQAATEERHMEELEQDREGSVEPRSRRDSFSSSVSYGSSVMGTHDEMLQVLKEKMRLEGQLESLSSEASQALKEKTELQAQLATVNAQLKAQVEQTQAGQERQSTLKTEVTTLRSNCSALEKAMVDLQTNLEGKNASLASLGNDLEVAEEQYQRLMVKVEEMQQSLNAKDNTVSELRQQMGGLQTQLQRVQSERNALQSRLKTSQAEVDSLQQLRLWYQQQLNLAQEARVRLQGEMANMQAGQMTQFGVLENLKIENVTLSHKLTETNHRSIKEKERIAVQLQSIEADMLTQEAAIHQIQEAKTMVEEDLQHKLEEFEEEREHLLKLANTATTLERELEQVKLVLFQKDSQLESLQREHLELMKQLTTTQETLQTKEQALNQLEARYQELQVQLEELQTDASAKEETLQYLQNEKIVLEVALQAARADKSELDEGAEKLGEEVLVASDTLDQLRQEVQVKATQIEALQHENGTLKKQAQKLKEQFMQQKVMVEAYRRDASSKEQLISELKASKKRLVAEVKDLKQELLKTEGEKKSAVQEQARLQKEVERVQQQMNGLEAHLQSVQTERDQLDSQLQSLQFDQNQLAAVTEENENLRKRVEQMQNEARTAISEQKVKMKRLGTDLTSAQKEMKAKHKAYENAVGILSRRLQEALAAKETAEAELDKLKAQVADGGNSQELQAKVKSLQGELQAVSQSKAMLEKELQEVITLTSTELEEYQEKVLELEDEQLQESRNFKKRIRRLEDANKKLALELEHEKGKLSGLGKSHSALREHANILEAALAKREADLVQLNLQVQAVLKRKEEEDQQMRQLVQTLQTALEKEKIKVKDLTEQVAEAKLEAAHNRRHYRAAVLELSEIKKDLQAKEELVKALEKEATTLAAQDEKHSEEVSRFREELADAHTQLQILQKQLDDELNKQPVTNQEVEDLKWEVEQKQREMEAQKQQLEMVEQCHQREMQSQQDMLQTIKVELEMVQEELNGTRKDKFMLQAKVGELRNSMKTVLQQNNQLKQDLKNSRLRKQRMDLKGESTPVTPVKIPDCPVPASLLDELLKPSTSVNKEPLNNLHNCLKQLKQEMDSLQKQMEEHTVTVTSLASPEDELQKLGLHDSSESSNKEDKEEMLPS", "length": 1494, "header": "tr|A2CEB4-1|A2CEB4_DANRE Isoform 1 of Golgin subfamily A member 3 OS=Danio rerio OX=7955 GN=golga3 PE=1 SV=1 CANONICAL=A2CEB4-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BC82-1", "url": "https://www.uniprot.org/uniprotkb/A2CEB4/entry#A0A8M2BC82-1", "sequence": { "sequence": "MENGNNGMVSIEAKPPQHPDAQHCKNPNSNTVESLKPERSLVTEKIPNGHVKAELLPNGEAMVEGQDVGGGSTPPSATPSPGSRLSDSSPSTELDPGVVSFPDSLERSEGSVHTGDALQSLRLSIPMQETELSSTDPCVEMENEEKIRQEARRRLEEQLKQYRAQRHTERTRRSTPKSRPFSTLDPELMLHPEGLPRANTVAMTKEYSFLRTSVPRGPKLGSLGIPSSREKKSKSSRSSKIHSLADYKTPESEGSGGAVSASADSSFTSLHSTISSVSTVSEISISSEANNHSESSQLIRDNISEVDGSESGFRADGNDSDSSSYSSVSTTGTYNMLSAIVNRPKAPYTVEGREIAAEAMGHFPSLQEVLQAATEERHMEELEQDREGSVEPRSRRDSFSSSVSYGSSVMGTHDEMLQVLKEKMRLEGQLESLSSEASQALKEKTELQAQLATVNAQLKAQVEQTQAGQERQSTLKTEVTTLRSNCSALEKAMVDLQTNLEGKNASLASLGNDLEVAEEQYQRLMVKVEEMQQSLNAKDNTVSELRQQMGGLQTQLQRVQSERNALQSRLKTSQAEVDSLQQLRLWYQQQLNLAQEARVRLQGEMANMQAGQMTQFGVLENLKIENVTLSHKLTETNHRSIKEKERIAVQLQSIEADMLTQEAAIHQIQEAKTMVEEDLQHKLEEFEEEREHLLKLANTATTLERELEQVKLVLFQKDSQLESLQREHLELMKQLTTTQETLQTKEQALNQLEARYQELQVQLEELQTDASAKEETLQYLQNEKIVLEVALQAARADKSELDEGAEKLGEEVLVASDTLDQLRQEVQVKATQIEALQHENGTLKKQAQKLKEQFMQQKVMVEAYRRDASSKEQLISELKASKKRLVAEVKDLKQELLKTEGEKKSAVQEQARLQKEVERVQQQMNGLEAHLQSVQTERDQLDSQLQSLQFDQNQLAAVTEENENLRKRVEQMQNEARTAISEQKVKMKRLGTDLTSAQKEMKAKHKAYENAVGILSRRLQEALAAKETAEAELDKLKAQVADGGNSQELQAKVKSLQGELQAVSQSKAMLEKELQEVITLTSTELEEYQEKVLELEDELQESRNFKKRIRRLEDANKKLALELEHEKGKLSGLGKSHSALREHANILEAALAKREADLVQLNLQVQAVLKRKEEEDQQMRQLVQTLQTALEKEKIKVKDLTEQVAEAKLEAAHNRRHYRAAVLELSEIKKDLQAKEELVKALEKEATTLAAQDEKHSEEVSRFREELADAHTQLQILQKQLDDELNKQPVTNQEVEDLKWEVEQKQREMEAQKQQLEMVEQCHQREMQSQQDMLQTIKVELEMVQEELNGTRKDKFMLQAKVGELRNSMKTVLQQNNQLKQDLKNSRLRKQRMDLKGESTPVTPVKIPDCPVPASLLDELLKPSTSVNKEPLNNLHNCLKQLKQEMDSLQKQMEEHTVTVTSLASPEDELQKLGLHDSSESSNKEDKEEMLPS", "length": 1493, "header": "tr|A0A8M2BC82-1|A2CEB4_DANRE Computationally mapped isoform of Golgin subfamily A member 3 OS=Danio rerio OX=7955 GN=golga3 PE=1 SV=1 CANONICAL=A2CEB4-1" }, "locus": {} }, { "isoform_ac": "A0A8M2BCD1-1", "url": "https://www.uniprot.org/uniprotkb/A2CEB4/entry#A0A8M2BCD1-1", "sequence": { "sequence": "MENGNNGMVSIEAKPPQHPDAQHCKNPNSNTVESLKPERSLVTEKIPNGHVKAELLPNGEAMVEGQDVGGGSTPPSATPSPGSRLSDSSPSTELDPASTDPCVEMENEEKIRQEARRRLEEQLKQYRAQRHTERTRRSTPKSRPFSTLDPELMLHPEGLPRANTVAMTKEYSFLRTSVPRGPKLGSLGIPSSREKKSKSSRSSKIHSLADYKTPESEGSGGAVSASADSSFTSLHSTISSVSTVSEISISSEANNHSESSQLIRDNISEVDGSESGFRADGNDSDSSSYSSVSTTGTYNMLSAIVNRPKAPYTVEGREIAAEAMGHFPSLQEVLQAATEERHMEELEQDREGSVEPRSRRDSFSSSVSYGSSVMGTHDEMLQVLKEKMRLEGQLESLSSEASQALKEKTELQAQLATVNAQLKAQVEQTQAGQERQSTLKTEVTTLRSNCSALEKAMVDLQTNLEGKNASLASLGNDLEVAEEQYQRLMVKVEEMQQSLNAKDNTVSELRQQMGGLQTQLQRVQSERNALQSRLKTSQAEVDSLQQLRLWYQQQLNLAQEARVRLQGEMANMQAGQMTQFGVLENLKIENVTLSHKLTETNHRSIKEKERIAVQLQSIEADMLTQEAAIHQIQEAKTMVEEDLQHKLEEFEEEREHLLKLANTATTLERELEQVKLVLFQKDSQLESLQREHLELMKQLTTTQETLQTKEQALNQLEARYQELQVQLEELQTDASAKEETLQYLQNEKIVLEVALQAARADKSELDEGAEKLGEEVLVASDTLDQLRQEVQVKATQIEALQHENGTLKKQAQKLKEQFMQQKVMVEAYRRDASSKEQLISELKASKKRLVAEVKDLKQELLKTEGEKKSAVQEQARLQKEVERVQQQMNGLEAHLQSVQTERDQLDSQLQSLQFDQNQLAAVTEENENLRKRVEQMQNEARTAISEQKVKMKRLGTDLTSAQKEMKAKHKAYENAVGILSRRLQEALAAKETAEAELDKLKAQVADGGNSQELQAKVKSLQGELQAVSQSKAMLEKELQEVITLTSTELEEYQEKVLELEDELQESRNFKKRIRRLEDANKKLALELEHEKGKLSGLGKSHSALREHANILEAALAKREADLVQLNLQVQAVLKRKEEEDQQMRQLVQTLQTALEKEKIKVKDLTEQVAEAKLEAAHNRRHYRAAVLELSEIKKDLQAKEELVKALEKEATTLAAQDEKHSEEVSRFREELADAHTQLQILQKQLDDELNKQPVTNQEVEDLKWEVEQKQREMEAQKQQLEMVEQCHQREMQSQQDMLQTIKVELEMVQEELNGTRKDKFMLQAKVGELRNSMKTVLQQNNQLKQDLKNSRLRKQRMDLKGESTPVTPVKIPDCPVPASLLDELLKPSTSVNKEPLNNLHNCLKQLKQEMDSLQKQMEEHTVTVTSLASPEDELQKLGLHDSSESSNKEDKEEMLPS", "length": 1457, "header": "tr|A0A8M2BCD1-1|A2CEB4_DANRE Computationally mapped isoform of Golgin subfamily A member 3 OS=Danio rerio OX=7955 GN=golga3 PE=1 SV=1 CANONICAL=A2CEB4-1" }, "locus": {} }, { "isoform_ac": "A2CEB4-1", "url": "https://www.uniprot.org/uniprotkb/A2CEB4/entry#A2CEB4-1", "sequence": { "sequence": "MENGNNGMVSIEAKPPQHPDAQHCKNPNSNTVESLKPERSLVTEKIPNGHVKAELLPNGEAMVEGQDVGGGSTPPSATPSPGSRLSDSSPSTELDPGVVSFPDSLERSEGSVHTGDALQSLRLSIPMQETELSSTDPCVEMENEEKIRQEARRRLEEQLKQYRAQRHTERTRRSTPKSRPFSTLDPELMLHPEGLPRANTVAMTKEYSFLRTSVPRGPKLGSLGIPSSREKKSKSSRSSKIHSLADYKTPESEGSGGAVSASADSSFTSLHSTISSVSTVSEISISSEANNHSESSQLIRDNISEVDGSESGFRADGNDSDSSSYSSVSTTGTYNMLSAIVNRPKAPYTVEGREIAAEAMGHFPSLQEVLQAATEERHMEELEQDREGSVEPRSRRDSFSSSVSYGSSVMGTHDEMLQVLKEKMRLEGQLESLSSEASQALKEKTELQAQLATVNAQLKAQVEQTQAGQERQSTLKTEVTTLRSNCSALEKAMVDLQTNLEGKNASLASLGNDLEVAEEQYQRLMVKVEEMQQSLNAKDNTVSELRQQMGGLQTQLQRVQSERNALQSRLKTSQAEVDSLQQLRLWYQQQLNLAQEARVRLQGEMANMQAGQMTQFGVLENLKIENVTLSHKLTETNHRSIKEKERIAVQLQSIEADMLTQEAAIHQIQEAKTMVEEDLQHKLEEFEEEREHLLKLANTATTLERELEQVKLVLFQKDSQLESLQREHLELMKQLTTTQETLQTKEQALNQLEARYQELQVQLEELQTDASAKEETLQYLQNEKIVLEVALQAARADKSELDEGAEKLGEEVLVASDTLDQLRQEVQVKATQIEALQHENGTLKKQAQKLKEQFMQQKVMVEAYRRDASSKEQLISELKASKKRLVAEVKDLKQELLKTEGEKKSAVQEQARLQKEVERVQQQMNGLEAHLQSVQTERDQLDSQLQSLQFDQNQLAAVTEENENLRKRVEQMQNEARTAISEQKVKMKRLGTDLTSAQKEMKAKHKAYENAVGILSRRLQEALAAKETAEAELDKLKAQVADGGNSQELQAKVKSLQGELQAVSQSKAMLEKELQEVITLTSTELEEYQEKVLELEDEQLQESRNFKKRIRRLEDANKKLALELEHEKGKLSGLGKSHSALREHANILEAALAKREADLVQLNLQVQAVLKRKEEEDQQMRQLVQTLQTALEKEKIKVKDLTEQVAEAKLEAAHNRRHYRAAVLELSEIKKDLQAKEELVKALEKEATTLAAQDEKHSEEVSRFREELADAHTQLQILQKQLDDELNKQPVTNQEVEDLKWEVEQKQREMEAQKQQLEMVEQCHQREMQSQQDMLQTIKVELEMVQEELNGTRKDKFMLQAKVGELRNSMKTVLQQNNQLKQDLKNSRLRKQRMDLKGESTPVTPVKIPDCPVPASLLDELLKPSTSVNKEPLNNLHNCLKQLKQEMDSLQKQMEEHTVTVTSLASPEDELQKLGLHDSSESSNKEDKEEMLPS", "length": 1494, "header": "tr|A2CEB4-1|A2CEB4_DANRE Isoform 1 of Golgin subfamily A member 3 OS=Danio rerio OX=7955 GN=golga3 PE=1 SV=1 CANONICAL=A2CEB4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 78, "start_aa": "Thr", "end_pos": 78, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr78", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A2CEB4", "url": "https://www.uniprot.org/uniprotkb/A2CEB4" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "A2CEB4", "url": "https://www.uniprot.org/uniprotkb/A2CEB4" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] }, { "title": "The Golgi matrix protein giantin is required for normal cilia function in zebrafish.", "journal": "Biol. Open", "date": "2017", "authors": "Bergen Dylan J M, Stevenson Nicola L, Skinner Roderick E H, Stephens David J, Hammond Christina L", "evidence": [ { "database": "UniProtKB", "id": "A2CEB4", "url": "https://www.uniprot.org/uniprotkb/A2CEB4" } ], "reference": [ { "type": "PubMed", "id": "28546340", "url": "https://glygen.org/publication/PubMed/28546340" } ] } ], "pathway": [ { "id": "dre:570879", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570879", "resource": "KEGG Pathway" }, { "id": "R-DRE-9696270", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9696270", "resource": "Reactome", "description": "RND2 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZGC2-1", "protein_name": "Golgin A3", "gene_name": "GOLGA3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MESSSVQQDVLLDNRSSSGAPGTSQEHGDCNANSALPATGDEVNTSSVNLSEVPNEEGSLELNSKADACQNGPELLFPDSPISFDPTSSPQGQESSPGVPGFHDSLRKSQGTSAEGVALRKEALQSLKLSLPMQETELCSVESSLPLENEEQIRLQARRRLEEQLRQYRVKRHQERSNQSTSKSRPSSTLDPELMLNPEILPRASTVAMTKEYSFLRTSVPRGPKLGSLGLPASSKERKSSKSSKSSKIRSLADYRTEDSGSGSSAGNLMATDLPGGTLKQSRSGPASVVSEISLPFDTDDRIENSSLAGDSISEIDGSEAGMRLDGNESDSSTYSSVSGKGLCNNLPNSEGKERIPYTINGQKIHPDAIGQFPSISEVLQAAAVEHQAQEQEFNGEIRSRRDSISSSVSMESSVAGTHDEMLQVLKEKMRLEGQLEALSAEANQALKEKAELQAQLAALNMKLQAQVEHSQSSQQKQESLSSEVATLKQSCWDLERAMADLQNTLEAKNASLASSNNDLQLAEEQYQRLMLKVEDMQKSVLTRDSTVHDLRQQLASLQSQLQKVQLERTTLTNKLKASETEITSLQNVRQWYQQQLVLAQEARVRLQSEMANIQAGQMTQAGVLEHLKLENVALSQQLTETQHRSIKEKERIAAQLQNIEADMLDQEAAFMQIQEAKTMVEEDLQRKLEEFEDEKEQLQKMADSAATLEQELDQVKLTLHQRDLQLESLQQEHLDLMKQFTMTQEMLHTKEQTLDDLQTQYDELKARLEEFQSDATSKDDMIQYLQNEKIVLEVALQTAKASQDQLDEGTKRLGEDTEVTSEILEQLRQEMAIRSSQVENLQQENGSLKKQVQKVKEQFLQQKVMVEAYRRDASSKDQLISELKATKKRLDSEMKELKRELLQIQVEKQSLETEHSKLQKEVTEVHQQMVEIENHLQSVQKERDEMETRLQSLQFDKEQMASLAEANQTLKLQVEQMQEEAKKAITEQKQKMKRLGSDLTSAQKEMKAKHKAYENAVSILSRRLQESLTAKESAEAELSKLKAQITDGGSNQIAQERIQALETELQAVRSSKLMLEKELQEVISLTSQELEEYREKVLELEDELQESRGFRRKIKRLEEINKKLALELEHERGKLTGLSQSNAALREHNNVLETALAKREADLVQLNLQVQAVLKRKEEEDQQMQQLIQALQASLEKEKSKVKDLKEQVAAAKADAAHNRRHYRAAALELNEVKKELHAKELLVQALQAEVDKLQVEDEKHSQEVSQFQQELAEARSQLQLLQKKLDDKLSEQPLVSQEVEDLKWEVEQKEREIGTLKQQLDMSEQRSHKELEGMQVVLQNIKTELEVVREDLSVTQKDKFMLQAKVSELKNSMKSLLQQNQQLKMDLKHGKMKKRKGENNSSNPVTPVKIPDCPVPAALLEELLKPSTAVSKEPLKNLNSCLRQLKQEMDSLQRQMEEHTITVHESMSSWTQIEEQLMDFTSTSPATASDQQERPALVETKHNCDVSDKEALAL", "length": 1516 }, "evidence": [ { "id": "A2CEB4", "url": "https://omabrowser.org/oma/group/A2CEB4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7GW86-1", "protein_name": "Golgin subfamily A member 3 isoform X1", "gene_name": "Golga3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLFRVFLVWAALTMDGVPVKQDGFWEDKSSNDISSCPEASPETLGSLALPPDQPNEVQSVSIEVNNSIFREGGSPDRSSQEALCQNGQFPDHPLSLDPTASPVGPDASAGVDGFHDNLRKSQGTSAEGSVRKEALQSLRLSLPMQETQLCSTASSLPLEKEEQVRLQARKRLEEQLIQYRVKRHRERSSQPATKMKLFSTLDPELMLNPENLPRASTVAVTKEYSFLRTSVPRGPKVGSLGLLAQSKEKKSSKSSKIRSLADYRTEDSSDSGGLGSTGDAVGGSLKQSRSSTSVVSEVSPSSETDNRVESASLAGDSVSEADGNESDSSSHSSFSTRGACGVLVNVAMPGAAYMVDGQEISVEALGQFPSIKDVLQSAAAQHQDQNQEVNGEVQSRRDSICSSVSMESSLAETQDEMLQVLKEKMRLEGQLEALSLEATQALQEKAELQAQLAALSTRLQAQVEHSHSSQQKQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRNILSKDNTVHDLRQQMAALQSQLHQVQLERTTLTSKLQASQAEITSLQHARQWYQQQLALAQEARVRLQGEVAHIQVGQMTQAGLLEHLKLENVSLSHQLTETQHRSIKEKERIAVQLQSIEADMLDQEAAFLQIKEAKTMVEEDLQRRLEEFEGEREQLQKVADAAASLEQQLEQVKLTLFQRDQQLAALQQEHLDVIKQLTSTQEALQSKGQSLDELHSRYDELQARLEELQREADSREDTIHFLQNEKIVLEVALQSARNDKEELDRGTQHLEEDTEETSGILEQLRQELAVKSNQVEHLQQETASLRKQIQKVKEQFLQQKVMVEAYRRDATSKDQLISELKATKKRLDSEMKELRQELIKVHGEKKTVEVEHSRLQKEMSLVHQQMADLEGHLQSVQKERDEMETHLQSLQFDKEQMVALTEANETLKKQIEELQQEAKKAITEQKQKMKRLGSDLTSAQKEMKTKHKAYENAVSILSRRLQEALATKEATDAELSQLRAQSTGGSSDPVLHEKIRALEVELQNVGQSKILLEKELQEVITMTSQELEESREKVLELEDELQESRGFRRKIKRLEESNKKLALELEHERGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKQLVEALQASLEKEKMKVNSMKEQMAAAKVEAGHNRRHFKAATLELSEVKKELQAKEHLVQTLQAQADELQIQEGKHSQEIAHFQTELAEARTRLQFLQKQLDEQMSQQPTGSQEMENLKWELDQKEREIQSLKQQLDLTEQHGKKELESTQQTLQTIRSELEMVQEDLSETQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKKKEPKGESNSSSPATPIKIPDCPVPASLLEELLRPPPAVSKEPLKNLNSCLQQLKQEMDSLQRQMEEHTITVHESLSSWAQAEAAPAEHAHPRGDTKPHSQNSVPREGLGQ", "length": 1501 }, "evidence": [ { "id": "A2CEB4", "url": "https://omabrowser.org/oma/group/A2CEB4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9SFD3-1", "protein_name": "Golgin A3", "gene_name": "GOLGA3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDSAAAMQEGLVEDRSSSGSSAQPEGPPKPPGSLAPLDQWDEAQCASAKVNRTSDEGRQGDTCLNGPTPQFPEPPSPSGPDASPGVAGFHDNLRKSQGTSAEGIVRKEALQSLRLSLPMQETQLCSTEASLPLEKEEQVRLQARKRLEEQLKQYRVKRQQERSSQPVTKTRLFSTLDPELMLNPETLPRASAVAMTKEYSFLRTSVPRGPKVGSLGLLAHPKEKKSSKSSKIRSLADYRTEDSDVRNSGGNVPAPDSTRGSLKQNRGSGTSVVSEVSLCPEADDRLENASLTGDNVSEADGTESDSSSYSSVSARGTPGIPANMGGTREAPYMVSGREIAVGALGQFPSISDVLQAAAAEHQEQRQEVNGETRSRTNSICSSVSLESSVAETHDEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALHTRLQAQLEHSHSSQQRQDSLSSEVDTLKQSCWDLEQAMTDLQNMLEAKNASLASSNSDLQVAEEQYQRLMAKVEEMQRSILSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEIASLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMSQAGLLEHLKLENVSLSHQLTETQQRSIKEKERIAAQLQGIEADMLDQEAAFVQIQEAKTMVEEDLQRRLEEFEDEKEQLQKMVASAAVLEQQLEQVKLTLHQRDQQLEALQQEHLDLLKQFTSTQETLQTREQSLGDLQVRYDELQARLDELQGEAASREDAIQALQNEKIVLEVALQAAHSSREEFDRGAKRLEEGAQDTSDTLEQLRQELAIKSSQVEHLQQEAGALKKQTQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATKKRLDSEVKELRQELMKLQGEKRSVEVEHSRLQKEMSQIQQQVVDLEGHLQSAQRERDEMETQLQSLQFDKEQMVAVTEANEVLKKQIEELQQEATKAITEQKQKMKRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAAEAELSQLRAQAAAGGSDLTLHERVQVLEAELQAVGHSKMMLERELQEVISLTGQELEEQREKVLELEDELQESRGFRRKIKRLEESNKKLALELEHERGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKQLVQALQAALQKEKVMVHSLEEQVAAAKAEAGHNRRHFKAATLELSEVKKELQAKEQEVQRLQAEADGLQIQEGKHSQEIAEFQAELAEARTQLQLLQKQLDEQLSKEPIGNQEMENLKWEVDQKEREIQSLKQQLDLTEHQSKQELDGIQQSLQNIKSELEMVREDLSMTQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKTRKEPKGEASSSSPVTPVKIPDCPVPASLLEELLRPPPAVSKEPLKNLNSCLQQLKQEMDSLQRQMEAHAVTVHESLSSWTQGDPASPSPPGDHANPRGDTERHGQGRASQEGLGTVTTEHPHPECL", "length": 1496 }, "evidence": [ { "id": "A2CEB4", "url": "https://omabrowser.org/oma/group/A2CEB4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D3ZLD5-1", "protein_name": "Golgin A3", "gene_name": "Golga3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGASAKQDGLWENKSSSDISSCPEASLETVGSLAQLPDQQDTAQDGSVEVNRVFKEEGSPDRSSQVPICQNGQIPDLQLSLDPTTSPVGPDASTGVDGFHDNLRKSQGTSAEGSVRKEALQSLRLSLPMQETQLCSTASSLPLEKEEQVRLQARKRLEEQLMQYRVKRHRERSSQPATKMKLFSTLDPELMLNPENLPRASAVAVTKEYSFLRTSVPRGPKVGSLGLLAHSKEKKNSKSSKIRSLADYRTEDPSDSGGLGSTADAVGSSLKQSRSSTSVVSEVSPSCETDNRAESASLAGDSVSEADGNESDSSSHSSFSARGACAVLGNVGTPGAAYVVDGQEISAEALGQFPSIKDVLQAAAAQHQDQNQEANGEVQSRRDSICSSVSMESSFAEPQEELLQILKDKRRLEGQVEALSLEASQALQEKAELQAQLAALSTRLQAQVEHSHSSQQKQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEAMQRNILSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLQASQAEITSLQQARQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSHQLTETQHRSIKEKERIAVQLQSIEADMLDQEAAFVQIREAKTMVEEDLQRKLEEFEGEREQLQKVADAAASLEQQLEQVKLTLFQRDQQLAALQQEHLDVIKQLTSTQEALQAKGQSLDDLQTRYDELQARLEELQREADSREDAIHFLQNEKIVLEVALHSARSDKEELDRGARRLEEDTEETSGLLEQLRQDVAVKSNQVEHLQQETATLRKQMQKVKEQFLQQKVMVEAYRRDAASKDQLINELKATKKRLDSEMKELRQELIKLHGEKKTVEVEHSRLQKDMSLVHQQMAELEGHLQSVQKERDEMEIHLQSLKFDKEQMIALTEANETLKKQIEELQQEAKKAITEQKQKMKRLGSDLTSAQKEMKTKHKAYENAVSILSRRLQEALANKEATDAELNQLRAQSTGGSSDPALHEKIHALEVELQNVGQSKILLEKELQEVITMTSQELEESREKVLELEDELQESRGFRRKIKRLEESNKKLALELEHERGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKQLVQALQISLEKEKTEVSSLKEQMAAARVEAGHNRRHFKAATLELSEVKKELQAKEHLVQTLQAEVDELQIQEGKHSQEIAQFQTELAEARTQLQLLQKKLEEQRSQQPTGSQEMEDLKWELDQKEREIQSLKQQLDLTEHQGKKELEGTQQTLQTIKSELETVQEDLSETQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKKKEPKGESSSSSPATPIKIPDCPVPASLLEELLRPPPAVSKEPLKNLNSCLQQLKQEMDSLQRQMEEHTITVHESLSSWAQVEAAPAEHAHARGDTKVHNQNSVPGEGLGQ", "length": 1487 }, "evidence": [ { "id": "HGNC:4426", "url": "https://alliancegenome.org/gene/HGNC:4426#orthology", "database": "AGR" }, { "id": "A2CEB4", "url": "https://omabrowser.org/oma/group/A2CEB4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RI72-1", "protein_name": "Golgin A3", "gene_name": "GOLGA3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGVVAMQDGPEDRSSNGPEALPKPPGSLALLDQQEEAQCTNVEVNRASDEGGSQGDTCQNGPMPQFPDPPSSVGPDASPGVAGFHDNLRKSQGTSAEGSGRKEALQSLRLSLPMQETQLCSTEASLPLEKEEQVRLQARKRLEEQLKQYRVKRQQERSSQPVTKTRLFSTLDPELMLNPETLPRASAVAMTKEYSFLRTSVPRGPKVGSLGLLAHPKEKKSSKSSKIRSLADYRTEESDAQNSGGSVPAVDSARASLKQNRSSGTSVVSEVSLCPEADDRLENASLTGDNVSEADGNESDSSSYSSVSTRGALSLLANSLGTREAPYVVSGQEVAAAALGQFPSISDVLQAAAAEHQDQRQEVNGETRSRADSICSSVSMESSVAETHDEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTRLQAQVEHSHNSQQRQDSLSSEVDTLKQSCWDLEQAMADLQNMLEAKNASLASSNSDLQVAEEQYHRLMAKVEEMQRSMLSKDNTVHDLRQQMTALQSQLRQVQLERTALSSKLQASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSHQLTETQQRSIKEKERIAAQLQGIEADMLDQEAAFVQIQEAKTMVEEDLQRRLEEFEDEKEQLQKMVASVATLEQQLEQVKLTLHQRDQQLEALQQEHLDLLKQFTSTQENLQAREQALGDLRVRCDELQARLDELQGEAASRDDTICVLQNEKIVLEVALQAARREELDPGSKRQEESTEETSETLERLREELAIKSSQVEHLQQEAATLKKQTQKIKEQFLQQKVMVEAYRRDAASKDQLVSELKATKKRLDAEAKELRQELIRLQGEKRSVEVEHARLQKDVTQARQQVADLEGHLQSVQRERDQMEMNLQSLQFDKEQMVALTEANEVLKKQIEELQQEATKAITEQKQKMKRLGSDLSSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAAEAELGQLRAQAASSSDDFPLHERIQALETELQTVGHSKTMLERELQEVISMTSQELEEQREKVLELEDELQEARGFRRKIKHLEESNKKLALELEHERGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKQLVQALQVALQKEKVTVRSLEEQVAAAKAEAGHNRRHFKAATLELSEVKKELQAKEQEVQRLQAEADGLQIQEGKHSQEIAQFQAELAEARTQLQFLQKQLDEQLSKEPIGNQEMENLKWEVDQKEREIQALKQQLDLTEQQSTKELEGVQQSLQNIKSELEMAREDLSMTQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKTRKELKEATSSSPVTPVKIPDCPVPASLLEELLRPPPAVSKEPLKNLNSCLQQLKQEMDSLQRQMEAHTVTVHESLSSWTQGDPTSPSPPGDHANPRGDTERPGQSRASGEGLGTAAERPHHECL", "length": 1488 }, "evidence": [ { "id": "A2CEB4", "url": "https://omabrowser.org/oma/group/A2CEB4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P55937-2", "protein_name": "Golgin subfamily A member 3", "gene_name": "Golga3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGASAKQDGLWESKSSSDVSSCPEASLETVGSLARLPDQQDTAQDASVEVNRGFKEEGSPDRSSQVAICQNGQIPDLQLSLDPTTSPVGPDASTGVDGFHDNLRNSQGTSAEGSVRKEALQSLRLSLPMQETQLCSTASSLPLEKEEQVRLQARKRLEEQLMQYRVKRHRERSSQPATKMKLFSTLDPELMLNPENLPRASTVAVTKEYSFLRTSVPRGPKVGSLGLLAHSKEKKNSKSSKIRSLADYRTEDPSDSGGLGSTADAVGSSLKQSRSSTSVVSEVSPSSETDNRVESASMTGDSVSEADGNESDSSSHSSLSARGACGVLGNVGMPGTAYMVDGQEISAEALGQFPSIKDVLQAAAAQHQDQNQEANGEVRSRRDSICSSVSMESSLAEPQDELLQILKDKRRLEGQVEALSLEASQALQEKAELQAQLAALSTRLQAQVEHSHSSQQKQDSLSSEVDTLKQSCWDLGRAMTDLQSMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRNILSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLQASQAEITSLQHARQWYQQQLTLAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSHQLTETQHRSIKEKERIAVQLQSIEADMLDQEAAFVQIREAKTMVEEDLQRRLEEFEGEREQLQKVADAAASLEQQLEQVKLTLFQRDQQLAALQQEHLDVIKQLTSTQEALQAKGQSLDDLHTRYDELQARLEELQREADSREDAIHFLQNEKIVLEVALQSAKSDKEELDRGARRLEEDTEETSGLLEQLRQDLAVKSNQVEHLQQETATLRKQMQKVKEQFVQQKVMVEAYRRDATSKDQLINELKATKKRLDSEMKELRQELIKLQGEKKTVEVEHSRLQKDMSLVHQQMAELEGHLQSVQKERDEMEIHLQSLKFDKEQMIALTEANETLKKQIEELQQEAKKAITEQKQKMKRLGSDLTSAQKEMKTKHKAYENAVSILSRRLQEALASKEATDAELNQLRAQSTGGSSDPVLHEKIRALEVELQNVGQSKILLEKELQEVITMTSQELEESREKVLELEDELQESRGFRRKIKRLEESNKKLALELEHERGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKQLVQALQVSLEKEKMEVNSLKEQMAAARIEAGHNRRHFKAATLELSEVKKELQAKEHLVQTLQAEVDELQIQDGKHSQEIAQFQTELAEARTQLQLLQKKLDEQMSQQPTGSQEMEDLKWELDQKEREIQSLKQQLDLTEQQGKKELEGTQQTLQTIKSELEMVQEDLSETQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKKKEPKGESNSSSPATPIKIPDCPVPASLLEELLRPPPAVSKEPLKNLNNCLQQLKQEMDSLQRQMEEHTITVHESLSSWAQVEAAPAEHAHPRGDTKLHNQNSVPRDGLGQ", "length": 1487 }, "evidence": [ { "id": "HGNC:4426", "url": "https://alliancegenome.org/gene/HGNC:4426#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q08378-1", "protein_name": "Golgin subfamily A member 3", "gene_name": "GOLGA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGASAEQDGLQEDRSHSGPSSLPEAPLKPPGPLVPPDQQDKVQCAEVNRASTEGESPDGPGQGGLCQNGPTPPFPDPPSSLDPTTSPVGPDASPGVAGFHDNLRKSQGTSAEGSVRKEALQSLRLSLPMQETQLCSTDSPLPLEKEEQVRLQARKWLEEQLKQYRVKRQQERSSQPATKTRLFSTLDPELMLNPENLPRASTLAMTKEYSFLRTSVPRGPKVGSLGLPAHPREKKTSKSSKIRSLADYRTEDSNAGNSGGNVPAPDSTKGSLKQNRSSAASVVSEISLSPDTDDRLENTSLAGDSVSEVDGNDSDSSSYSSASTRGTYGILSKTVGTQDTPYMVNGQEIPADTLGQFPSIKDVLQAAAAEHQDQGQEVNGEVRSRRDSICSSVSLESSAAETQEEMLQVLKEKMRLEGQLEALSLEASQALKEKAELQAQLAALSTKLQAQVECSHSSQQRQDSLSSEVDTLKQSCWDLERAMTDLQNMLEAKNASLASSNNDLQVAEEQYQRLMAKVEDMQRSMLSKDNTVHDLRQQMTALQSQLQQVQLERTTLTSKLKASQAEISSLQSVRQWYQQQLALAQEARVRLQGEMAHIQVGQMTQAGLLEHLKLENVSLSQQLTETQHRSMKEKGRIAAQLQGIEADMLDQEAAFMQIQEAKTMVEEDLQRRLEEFEGERERLQRMADSAASLEQQLEQVKLTLLQRDQQLEALQQEHLDLMKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKTKHKAYENAVGILSRRLQEALAAKEAADAELGQLRAQGGSSDSSLALHERIQALEAELQAVSHSKTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHEKGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQALQASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEADDLQIREGKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQKEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQKDKFMLQAKVSELKNNMKTLLQQNQQLKLDLRRGAAKTRKEPKGEASSSNPATPIKIPDCPVPASLLEELLRPPPAVSKEPLKNLNSCLQQLKQEMDSLQRQMEEHALTVHESLSSWTPLEPATASPVPPGGHAGPRGDPQRHSQSRASKEGPGE", "length": 1498 }, "evidence": [ { "id": "HGNC:4426", "url": "https://alliancegenome.org/gene/HGNC:4426#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-252", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-252#orthology", "database": "AGR" }, { "id": "A2CEB4", "url": "https://omabrowser.org/oma/group/A2CEB4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2CEB4", "url": "https://www.uniprot.org/uniprotkb/A2CEB4" } ], "pmid": "" }, { "name": "Golgi membrane", "id": "GO:0000139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000139", "evidence": [ { "database": "UniProtKB", "id": "A2CEB4", "url": "https://www.uniprot.org/uniprotkb/A2CEB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1350, "end_pos": 1352, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 840, "end_pos": 842, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 78 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1350, "end_pos": 1352 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 302, "end_pos": 304 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 485, "end_pos": 487 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 626, "end_pos": 628 }, { "start_pos": 840, "end_pos": 842 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2CEY8-1", "uniprot_ac": "A2CEY8", "uniprot_id": "A2CEY8_DANRE", "mass": { "chemical_mass": 89014.0, "monoisotopic_mass": 89014.0 }, "refseq": { "ac": "NP_001243557", "name": "uncharacterized protein LOC553498", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243557" }, "gene_names": [ { "name": "si:dkey-251i10.3", "type": "recommended", "evidence": [ { "id": "A2CEY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEY8" } ] }, { "name": "si:dkey-251i10.3", "type": "synonym", "evidence": [ { "id": "NP_001243557", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243557" } ] } ], "protein_names": [ { "name": "UTP14, U3 small nucleolar ribonucleoprotein, homolog A", "type": "synonym", "evidence": [ { "id": "NP_001243557", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243557" } ] }, { "name": "Uncharacterized protein LOC553498", "type": "synonym", "evidence": [ { "id": "A2CEY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEY8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC553498", "type": "synonym", "evidence": [ { "id": "NP_001243557", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243557" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01037318.1, GDQH01017475.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On Feb 15, 2012 this sequence version replaced XP_689811.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001243557", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243557" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CEY8", "url": "https://www.uniprot.org/uniprotkb/A2CEY8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-251i10.3", "url": "https://www.uniprot.org/uniprotkb/A2CEY8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-271", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-271", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000042520", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000042520", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "553498", "url": "https://www.ncbi.nlm.nih.gov/gene/553498", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:553498", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553498", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVIEPMD", "url": "https://omabrowser.org/oma/group/QVIEPMD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BCW9", "url": "https://www.orthodb.org/?gene=A0A8M2BCW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A2CEY8", "url": "https://www.orthodb.org/?gene=A2CEY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14150", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14150", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14150:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14150:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04615", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04615", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001243557", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243557", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BCW9", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BCW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BCW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BCW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2CEY8", "url": "https://www.uniprot.org/uniprotkb/A2CEY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2CEY8-1", "url": "https://www.uniprot.org/uniprotkb/A2CEY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-271", "url": "https://zfin.org/ZDB-GENE-060526-271", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVKRSSLQKTTPSEGVTSAMAADSGDEEELYTDPEQAISASEDEEGSDDERKHNKLLEAISSMGGRKRKKQSERSEASVQVSEFFVNAEGAGDKINLSDLLGVVEKTAGASNKTKKQLRNLQSTKETLELPLNKQQKEKIQRGIAYVKTAEEVSNWQNIIVQNQRAEQMVFPLKQEPSGPKRVEQVVAGWKVKTPLEQEIFQLLHSNSQPVLDPVLTPVEEASLKAMSLEEAKIRRAELQKARALQSYYEAKAKREKKIKSKQYHRVQKKAKRKEFLKQFDEMVKSNPQEALEELKKMEMSRMQERMSLKHQNSGKWAKSKAIMAKYDDSARKAMQEQLQMNKDLTQKIVVLSDDEQADEDLEAVPDFVNDPEPIIDPVNPWMRGQLTQEEPEVSCVTTDELQAAEEEKEDEEEELLGEFERKRKMRQADEAEDLIPTEEKTEHVSEVAGEDVVEISDNDDEEEEDDDDDEEEEKEEEEEEEEEDVSKFNSLFNLMRSEKTQKGQEDGEELLDEGQVRVRNMEDLEDLGEGFEPQPSTTPSVTQTAIADKTSEPQNKKGISLSEVLTKEAKVIKVPFLPTVVEHEETEHDEQLSIIKEAFAGDDVISDFMKDKKKQEEAGRPKVVDLTLPGWGEWGGIGLKPSRRKRKRFTKKMDPPPPRQDRKLPDVIISEKRNTSIAAHQVSHLPFPYENPAQFESTIRTPVGQTWNTQSVVKKMTTPKVVTKMGAIIEPMAKEDLIKGKSSTAAGKAPALTLGQRDKRAKVGEKRSSQKKPGKRAPKKKRKQ", "length": 785, "header": "tr|A2CEY8-1|A2CEY8_DANRE Isoform 1 of Uncharacterized protein LOC553498 OS=Danio rerio OX=7955 GN=si:dkey-251i10.3 PE=1 SV=1 CANONICAL=A2CEY8-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BCW9-1", "url": "https://www.uniprot.org/uniprotkb/A2CEY8/entry#A0A8M2BCW9-1", "sequence": { "sequence": "MVKRSSLQKTTPSEGVTSAMAADSGDEEELYTDPEQAISASEDEEGSDDERKHNKLLEAISSMGGRKRKKQSERSEASVQVSEFFVNAEGAGDKINLSDLLGVVEKTAGASNKTKKQLRNLQSTKETLELPLNKQQKEKIQRGIAYVKTAEEVSNWQNIIVQNQRAEQMVFPLKQEPSGPKRVEQVVAGWKVKTPLEQEIFQLLHSNSQPVLDPVLTPVEEASLKAMSLEEAKIRRAELQKARALQSYYEAKAKREKKIKSKQYHRVQKKAKRKEFLKQFDEMVKSNPQEALEELKKMEMSRMQERMSLKHQNSGKWAKSKAIMAKYDDSARKAMQEQLQMNKDLTQKIVVLSDDEQADEDLEAVPDFVNDPEPIIDPVNPWMRGQLTQEEPEVSCVTTDELQAAEEEKEDEEEELLGEFERKRKMRQADEAEDLIPTEEKKHVSEVAGEDVVEISDNDDEEEEDDDDDEEEEKEEEEEEEEEDVSKFNSLFNLMRSEKTQKGQEDGEELLDEGQVRVRNMEDLEDLGEGFEPQPSTTPSVTQTAIADKTSEPQNKKGISLSEVLTKEAKVIKVPFLPTVVEHEETEHDEQLSIIKEAFAGDDVISDFMKDKKKQEEAGRPKVVDLTLPGWGEWGGIGLKPSRRKRKRFTKKMDPPPPRQDRKLPDVIISEKRNTSIAAHQVSHLPFPYENPAQFESTIRTPVGQTWNTQSVVKKMTTPKVVTKMGAIIEPMAKEDLIKGKSSTAAGKAPALTLGQRDKRAKVGEKRSSQKKPGKRAPKKKRKQ", "length": 784, "header": "tr|A0A8M2BCW9-1|A2CEY8_DANRE Computationally mapped isoform of Uncharacterized protein LOC553498 OS=Danio rerio OX=7955 GN=si:dkey-251i10.3 PE=1 SV=1 CANONICAL=A2CEY8-1" }, "locus": {} }, { "isoform_ac": "A2CEY8-1", "url": "https://www.uniprot.org/uniprotkb/A2CEY8/entry#A2CEY8-1", "sequence": { "sequence": "MVKRSSLQKTTPSEGVTSAMAADSGDEEELYTDPEQAISASEDEEGSDDERKHNKLLEAISSMGGRKRKKQSERSEASVQVSEFFVNAEGAGDKINLSDLLGVVEKTAGASNKTKKQLRNLQSTKETLELPLNKQQKEKIQRGIAYVKTAEEVSNWQNIIVQNQRAEQMVFPLKQEPSGPKRVEQVVAGWKVKTPLEQEIFQLLHSNSQPVLDPVLTPVEEASLKAMSLEEAKIRRAELQKARALQSYYEAKAKREKKIKSKQYHRVQKKAKRKEFLKQFDEMVKSNPQEALEELKKMEMSRMQERMSLKHQNSGKWAKSKAIMAKYDDSARKAMQEQLQMNKDLTQKIVVLSDDEQADEDLEAVPDFVNDPEPIIDPVNPWMRGQLTQEEPEVSCVTTDELQAAEEEKEDEEEELLGEFERKRKMRQADEAEDLIPTEEKTEHVSEVAGEDVVEISDNDDEEEEDDDDDEEEEKEEEEEEEEEDVSKFNSLFNLMRSEKTQKGQEDGEELLDEGQVRVRNMEDLEDLGEGFEPQPSTTPSVTQTAIADKTSEPQNKKGISLSEVLTKEAKVIKVPFLPTVVEHEETEHDEQLSIIKEAFAGDDVISDFMKDKKKQEEAGRPKVVDLTLPGWGEWGGIGLKPSRRKRKRFTKKMDPPPPRQDRKLPDVIISEKRNTSIAAHQVSHLPFPYENPAQFESTIRTPVGQTWNTQSVVKKMTTPKVVTKMGAIIEPMAKEDLIKGKSSTAAGKAPALTLGQRDKRAKVGEKRSSQKKPGKRAPKKKRKQ", "length": 785, "header": "tr|A2CEY8-1|A2CEY8_DANRE Isoform 1 of Uncharacterized protein LOC553498 OS=Danio rerio OX=7955 GN=si:dkey-251i10.3 PE=1 SV=1 CANONICAL=A2CEY8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A2CEY8", "url": "https://www.uniprot.org/uniprotkb/A2CEY8" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A2CEY8", "url": "https://www.uniprot.org/uniprotkb/A2CEY8" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:553498", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553498", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AJ81-1", "protein_name": "UTP14A small subunit processome component", "gene_name": "Utp14a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSCVIGGSKNCFAAGKEVALSLASVLDPCELPATKMSAIKATKGLLALSQQDDLMDLPTNYPLSDSEDEAGSDGERKHQKLLEAIGSLSGKNRWKLPERSEAGLKVSEFNVSSEGSGEKLALSDLLEPLKSSSSLAAVKKQLNRVKSKKTLELPLHKGEVERVHREVAFSNTSQALSKWDSVVQKNRAAEQLVFPLEKEPTFVPMEHVFCEWKARSPLEQEIFNLLHKNKQPVTDPLLTPVEKASLKAMSLEEAKIRRAELQRARALQSYYEARARRMKKIKSKKAVEAGESALQKSGGGSESQPCQVPYWLPPSQPALVAILAPVYHKIVKKGKAQKALKDFEQLRKVDPDAALEELEKMEKARMLERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLAKNKELTQKLQVVSESEEERDAEEEEALVPDIVNEVQKAAHGPNPWMLRSCNHDAKENEIQADPEQLPEPAAPEFSKNEGDEKPVAEEGKLLEELEKRRSLRKRSELNHDAEPARDQKPKDSTNQEVLSELRALSKKLSKENHPFEKQKESPAKTVGLVQEEEPGPEEDEPLLLQRPERVRTLEELEELGKEYSLPNKELSRPSVEGEQMRTNPQNQTKGKNKKEQMISLQNLLTTRTPSVTSLALPTTVEELDDEVKRNQKQMIKEAFAGDDVIKEFLKEKREAVQANKPKDVDLTLPGWGEWGGMDLKPSAKKRRRFLIKAPEGPPRKDKNLPNVIINEKRNIHIAAHQVRVLPYPFTHHQQFERTIQNPIGSTWITQRAFQKLTAPKVVTKPGHIIKPITADDVGRQSSPRSDLSVMQTNPKRHCKHQKQLKKKAL", "length": 841 }, "evidence": [ { "id": "A2CEY8", "url": "https://omabrowser.org/oma/group/A2CEY8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4JHI1-1", "protein_name": "U3 ribonucleoprotein (Utp) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGEKRKSTSKTLAKNKKRKGPHLPNSILKTIANEKRPLNSDEDDDEIDSDDENVDLYEYEEGVPEEESKKNNRYDRVDNYDYELPEDFEDENVESDDDEDGGNSENEEGEGDDDRHTRMLQGLTGMPSAAFQEESKKRPVLYTEAYPESEFNPTRDVLEGKGLISVEDLLAPLEGKPGFNDLNKRINRMQKDTQSVVHAPLPKPERERLERKAVKGLVEKDFNKWVHLVKRNREAPTVYFNQPVNVGYSTVGAIASEFQPRTEFEKKMASVLKDNELGEAHKEDGAKLLELNEVSMEDHIKYRDHIAKMRSLLFRHELKSKRIKKIKSKTYHRLKGKDLKKSAMGALMDPEMAKEEAIKQETRRVEERMTLKHKNTGKWAKRMLSRGLTERYDGTRAAISEQLQINATLSRKMNSTNDGSSSDESDDEEELSCGSDQDTPSKLIAKAREKTLKTMEDDDVPNSGLLSLPFMARAMKKKNEEANEEAKRAFGEYKELENFGGEDNPKKSADVSGRRVFGATSKVEAPKESKKDSDNFYDNSDSDNDMEGIENNDLGAVGDTASPARNTGAITETEKCCGDVENPASKTTFDVALFASGSWKKMKGSQNAESKKAPKTRVPISKGQDKKESRDEESEDSESEAEQMVDGILTSASKETYEIPSQAELIQRAFAGDDVVEEFEKDKQEVLNQEVPEPEKPVLVPGWGQWTNVQKKRGLPSWMVREHEDANKKRKLDLKTRKDYRLRNVIISEKVDKKADKLHTTTLPFPYTSKEVFEHSMRMPIGPEFNPATIVGALNRPEVVKKAGVIIKPVKFEEVNPNEKADDENPRSHQKQRPKKGSKTSKGQGKNKSKLKTKA", "length": 855 }, "evidence": [ { "id": "A2CEY8", "url": "https://omabrowser.org/oma/group/A2CEY8/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q04500-1", "protein_name": "U3 small nucleolar RNA-associated protein 14", "gene_name": "UTP14", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAKKKSKSRSKSSRRVLDALQLAEREINGEFDNSSDNDKRHDARRNGTVVNLLKRSKGDTNSDEDDIDSESFEDEELNSDEALGSDDDYDILNSKFSQTIRDKKENANYQEEEDEGGYTSIDEEDLMPLSQVWDMDEKTAQSNGNDDEDASPQLKLQDTDISSESSSSEESESESEDDEEEEDPFDEISEDEEDIELNTITSKLIDETKSKAPKRLDTYGSGEANEYVLPSANAASGASGKLSLTDMMNVIDDRQVIENANLLKGKSSTYEVPLPQRIQQRHDRKAAYEISRQEVSKWNDIVQQNRRADHLIFPLNKPTEHNHASAFTRTQDVPQTELQEKVDQVLQESNLANPEKDSKFEELSTAKMTPEEMRKRTTEMRLMRELMFREERKARRLKKIKSKTYRKIKKKELMKNRELAAVSSDEDNEDHDIARAKERMTLKHKTNSKWAKDMIKHGMTNDAETREEMEEMLRQGERLKAKMLDRNSDDEEDGRVQTLSDVENEEKENIDSEALKSKLGKTGVMNMAFMKNGEAREREANKETLRQLRAVENGDDIKLFESDEEETNGENIQINKGRRIYTPGSLESNKDMNELNDHTRKENKVDESRSLENRLRAKNSGQSKNARTNAEGAIIVEEESDGEPLQDGQNNQQDEEAKDVNPWLANESDEEHTVKKQSSKVNVIDKDSSKNVKAMNKMEKAELKQKKKKKGKSNDDEDLLLTADDSTRLKIVDPYGGSDDEQGDNVFMFKQQDVIAEAFAGDDVVAEFQEEKKRVIDDEDDKEVDTTLPGWGEWAGAGSKPKNKKRKFIKKVKGVVNKDKRRDKNLQNVIINEKVNKKNLKYQSSAVPFPFENREQYERSLRMPIGQEWTSRASHQELIKPRIMTKPGQVIDPLKAPFK", "length": 899 }, "evidence": [ { "id": "A2CEY8", "url": "https://omabrowser.org/oma/group/A2CEY8/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3T0Q8-1", "protein_name": "U3 small nucleolar RNA-associated protein 14 homolog A", "gene_name": "UTP14A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNANQAAESNLLASNQQKELEDLPKDYPLSTSEDEGDKDEERKHQKLLESISSLNGKDRQKLADRSEASLKVSEFSVSSEGSGEKLVLSDLLEPVKTSSSLAAVKKQLNRVKSKKTVELPLHREEIERIHREVAFNKSSQILSKWDPVVLKNRQAEQLVFPLSKPQSAFAPIEHVVNGWKAGTPLEQEIFNLLHKNKQPVTDPLLTPVEKASLKAMSLEEVKMRRAELQRARALQSYYEARARREKRIKSKKYHRILKKGKAKQALKDFEKLQKVNPAAALEELEKLDKARMMERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLARNKELTQKVRAASESEEEGEGQEEEEEPLVPDLVNEVQIKANGLNPWMFRNHFIDAKEAEVQKDLEDPAEPEAQETSESEEEKAVVEEETLLKEFEERRSLRQKSELNHMAEPVHRRVTKDPSSQEVLSDLRALCQKLRTENHQSGKQELSSARTAQREEPAREEEEPMLLQRPERARTLDELEELGREGCVENEELPRTAVEGLQLEKNLSNHIGAPKEKKRKEQMIDLQNLLTTKSPSVKSLAVPTTVQELEDEEERDQRQIIKEAFAGDDVIRDFLKEKREAVEASKPKDLDLTLPGWGEWGGIGLKPSAKKRRRFLIKAPEGPPRKDKNLPNVIINEKRNTHAAAHQVQVLPHPFTHHQQFERTIQTPVGSTWNTQRAFQKLTMPKVVTKPGHIIKPIKAEDVGYRSSSRSDLSVVQRNPKRLSIRHKKHLENNCVD", "length": 770 }, "evidence": [ { "id": "A2CEY8", "url": "https://omabrowser.org/oma/group/A2CEY8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q640M1-1", "protein_name": "U3 small nucleolar RNA-associated protein 14 homolog A", "gene_name": "Utp14a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSIKATKGLLALSQQDDLMDLTSNYPLSASEDEGDSDGERKHQKLLEAIGSLSGKNRWKLPERSEAGLKVSEFNVSSEGSGEKLALSDLLGPLKPSSSLAAVKKQLSRVKSKKTLELPLHKREVEQIHREVAFSKTSQTLSKWDSVVQKNREAEQLVFPLEKEPSSFAPMEHVFREWKARTPLEQEVFNLLHKNKQPVTDPLLTPVEKASLKAMSLEEAKIRRAELQRARALQSYYEARARRMKKIKSKKYHKIVKKGKAKKALKDFEQLRKVDPDAALEELEKMEKARMMERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLAKNKELTQKLQVVSESEEEGGADEEEALVPDIVNEVQKTADGPNPWMLRSCSRDAKENEIQADSEQLPESAAHEFPENEENDKPVAEEDELLKELEKRRSLRKRSELNQAAEPLGNQETKDSTSQEVLSELRALSKKLSKENHLSKKQKKSPAKAVDLVWEEEPAPEEDEPLLLQRPERMRTLEELEELGKEDSLPNKERPRPSVEGEQVRRNPQNHSKGKNKKEQMISLQNLLTTRTPSVTSLALPTTVEELEDEGARDQKQMIKEAFAGDDVIKEFLKEKREAIQANKPKAVDLTLPGWGEWGGMNLKPSARKRRRFLIKAPEGPPRKDKNLPNVIISEKRNIHAAAHQVRVLPYPFTHHQQFERTIQNPIGSTWNTQRAFQKLTAPKVVTKPGHIIKPITAEDVDCRSSPRSDVPVMQSNPKQHSKHQKQRKKSSIG", "length": 767 }, "evidence": [ { "id": "A2CEY8", "url": "https://omabrowser.org/oma/group/A2CEY8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BVJ6-1", "protein_name": "U3 small nucleolar RNA-associated protein 14 homolog A", "gene_name": "UTP14A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTANRLAESLLALSQQEELADLPKDYLLSESEDEGDNDGERKHQKLLEAISSLDGKNRRKLAERSEASLKVSEFNVSSEGSGEKLVLADLLEPVKTSSSLATVKKQLSRVKSKKTVELPLNKEEIERIHREVAFNKTAQVLSKWDPVVLKNRQAEQLVFPLEKEEPAIAPIEHVLSGWKARTPLEQEIFNLLHKNKQPVTDPLLTPVEKASLRAMSLEEAKMRRAELQRARALQSYYEAKARREKKIKSKKYHKVVKKGKAKKALKEFEQLRKVNPAAALEELEKIEKARMMERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLSKNKELTQKLQVASESEEEEGGTEDVEELLVPDVVNEVQMNADGPNPWMLRSCTSDTKEAATQEDPEQLPELEAHGVSESEGEERPVAEEEILLREFEERRSLRKRSELSQDAEPAGSQETKDSGSQEVLSELRVLSQKLKENHQSRKQKASSEGTIPQVQREEPAPEEEEPLLLQRPERVQTLEELEELGKEECFQNKELPRPVLEGQQSERTPNNRPDAPKEKKKKEQMIDLQNLLTTQSPSVKSLAVPTIEELEDEEERNHRQMIKEAFAGDDVIRDFLKEKREAVEASKPKDVDLTLPGWGEWGGVGLKPSAKKRRRFLIKAPEGPPRKDKNLPNVIINEKRNIHAAAHQVRVLPYPFTHHWQFERTIQTPIGSTWNTQRAFQKLTTPKVVTKPGHIINPIKAEDVGYRSSSRSDLSVIQRNPKRITTRHKKQLKKCSVD", "length": 771 }, "evidence": [ { "id": "A2CEY8", "url": "https://omabrowser.org/oma/group/A2CEY8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VUR2-1", "protein_name": "U3 small nucleolar RNA-associated protein 14 homolog A", "gene_name": "Dmel\\CG12301", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDDEEHYEPKAHKKLLQAIGSLGKVQHIQKSTRDERQSLQDEFQLVKGVSSAETDHAPRAVGLNDLVDILRTSTKHSQTGKKLKNIHGSKKVLQKPLEKPAADRIKRTIGYEGVTKKLGRWDAVVAQQRSAETQIFPLPSETVYVNTAANARPLNTRVKSNLAQELEANNRKLRELRKAQIGDTTDEKELAKQERLLLQKKLTRDELFARRKELAYLKMRESQKSAKARMQNKIKSKKFHKLQKRQKMLEQMKEFELLQKTDPEAALEKLNALEKSRVQERASLRHKNTGTWAKNLQIRAKYDKDVRKDLAEQLAVSRELTQKKQVSDSEDETTKKRVLPEEEDNDYDPFNPWTKRKATEQTENGNGESEGSNWRQYWTKRNKNEKLLEEHRRDLEGVQDNDEQEEKETIRKPLIEVKPAKKKLKKSKVKIENGWEVEDICPTDQKEAKASPNSKAIDDIFEKHEDHIRAKLNKKMEKLRERINKLKEVPVKGKKAKKKDVLQNLKSLALKKTKQQIEIDEPLNYEEDKNSQNNIPAHVEGNTESTEIPAVDTIDPNKVTTLVFTQKKGNSGGFNDALIDDEAAEYDEEDAAAERQLTISQAFEDDDIVADFNRDKSKDSELKNTELQLALPGWGSWAGAGISKEVMERRNKRLLLKLAAPEKRRDENKDNLYLNESASKQARQHMVSSIPFPFRSLADYEASIRAPVGRNFVPETAFRMLTRPAVITRKGQVIEPMTESELVKPDRRLRHIVDRRIKRIPKVPPKAKIA", "length": 771 }, "evidence": [ { "id": "A2CEY8", "url": "https://omabrowser.org/oma/group/A2CEY8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA processing", "id": "GO:0006364", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006364", "evidence": [ { "database": "UniProtKB", "id": "A2CEY8", "url": "https://www.uniprot.org/uniprotkb/A2CEY8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "small-subunit processome", "id": "GO:0032040", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032040", "evidence": [ { "database": "UniProtKB", "id": "A2CEY8", "url": "https://www.uniprot.org/uniprotkb/A2CEY8" } ], "pmid": "" }, { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A2CEY8", "url": "https://www.uniprot.org/uniprotkb/A2CEY8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 675, "end_pos": 677, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 675, "end_pos": 677 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2BIN4-1", "uniprot_ac": "A2BIN4", "uniprot_id": "A2BIN4_DANRE", "mass": { "chemical_mass": 57643.0, "monoisotopic_mass": 57643.0 }, "refseq": { "ac": "NP_001003613", "name": "splicing regulatory glutamine/lysine-rich protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003613" }, "gene_names": [ { "name": "srek1", "type": "recommended", "evidence": [ { "id": "A2BIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIN4" } ] }, { "name": "srek1", "type": "synonym", "evidence": [ { "id": "NP_001003613", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003613" } ] }, { "name": "zgc:100974", "type": "synonym", "evidence": [ { "id": "NP_001003613", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003613" }, { "id": "A2BIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIN4" } ] } ], "protein_names": [ { "name": "Splicing regulatory glutamine/lysine-rich protein 1", "type": "recommended", "evidence": [ { "id": "A2BIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIN4/entry#names_and_taxonomy" } ] }, { "name": "Serine/arginine-rich-splicing regulatory protein 86", "type": "synonym", "evidence": [ { "id": "A2BIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIN4/entry#names_and_taxonomy" } ] }, { "name": "Splicing factor, arginine/serine-rich 12", "type": "synonym", "evidence": [ { "id": "A2BIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIN4/entry#names_and_taxonomy" } ] }, { "name": "splicing regulatory glutamine/lysine-rich protein 1", "type": "synonym", "evidence": [ { "id": "NP_001003613", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003613" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01039650.1, SRR26395014.1007097.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505376 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1 and EH454239.1. On or before Nov 5, 2015 this sequence version replaced XP_005165711.1, NP_001003613.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001003613", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003613" } ] }, { "annotation": "Participates in the regulation of alternative splicing by modulating the activity of other splice facors. Inhibits the splicing activity of SFRS1, SFRS2 and SFRS6. Augments the splicing activity of SFRS3.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9Q8F0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8F0#function" }, { "database": "UniProtKB", "id": "ARBA00058989", "url": "https://www.uniprot.org/uniprotkb/ARBA00058989#function" }, { "database": "UniProtKB", "id": "A0A8M2BCX1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BCX1#function" }, { "database": "UniProtKB", "id": "A2BIN4", "url": "https://www.uniprot.org/uniprotkb/A2BIN4#function" }, { "database": "UniProtKB", "id": "A0AC58JIC7", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIC7#function" }, { "database": "UniProtKB", "id": "A0AC58JIC9", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIC9#function" }, { "database": "UniProtKB", "id": "A0AC58JIE2", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIE2#function" }, { "database": "UniProtKB", "id": "A0AC58JIF1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIF1#function" }, { "database": "UniProtKB", "id": "A0AC58JIF2", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIF2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BIN4", "url": "https://www.uniprot.org/uniprotkb/A2BIN4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "srek1", "url": "https://www.uniprot.org/uniprotkb/A2BIN4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040801-132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-132", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000009764", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000009764", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12260", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12260", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12519", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12519", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "445219", "url": "https://www.ncbi.nlm.nih.gov/gene/445219", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034192", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034192", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:445219", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:445219", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MYPADEF", "url": "https://omabrowser.org/oma/group/MYPADEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BCX1", "url": "https://www.orthodb.org/?gene=A0A8M2BCX1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0AC58JIC9", "url": "https://www.orthodb.org/?gene=A0AC58JIC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A2BIN4", "url": "https://www.orthodb.org/?gene=A2BIN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32343", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32343", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32343:SF71", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32343:SF71", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001003613", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003613", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BCX1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BCX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BCX1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BCX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q8F0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q8F0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q8F0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JIC7", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JIC7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JIC9", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JIC9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JIE2", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JIE2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JIF1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JIF1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JIF2", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JIF2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JIF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BIN4", "url": "https://www.uniprot.org/uniprotkb/A2BIN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BIN4-1", "url": "https://www.uniprot.org/uniprotkb/A2BIN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040801-132", "url": "https://zfin.org/ZDB-GENE-040801-132", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSGMPGTNVIQITNLSAAVSSDQMRTLFGFLGDIDELRLYPPDNAPLSFSSKVCYIKYREPSSVGVAQHLTNTVFIDRALIVVPCAEGKIPEEAKALSLLAPATPVASLMSGGGLLPIPSPSTLQNRSLPLANLGVLKSSLDTSVATLSAVSAQPPLMGNVDPSKVDEIRRTVYVGNLNSQSTTADQLLKFFKQVGDVKFVRMAGDETQPTRFAFVEFADQDSVARALTYNGVMFGDRPLKINHSNNAIVKPPELTPQAAAKELEDVMKKVREAQSTIAAAIEPENELPSSSRSRHSRRSRSHSCSPSNSRRKRSRSRHRGHPSKRSRQRFNDSCGSHRRHSRSRERRRSQSRSHSRGRRKDKDSKGRKDDDWDEKRLRDKTGRSPPKCYVGSRRSRSTSRGHKKRSRSPSRSPRQRARSPTPTKRGKREKKREKGWDSSRERAESSAFRRKSRDSEYKAKPSQRERVYEQMEHEYDSEMDGSGSMVSDDRSPPAHLNGSYRSSYAEEDNLFAAE", "length": 515, "header": "tr|A2BIN4-1|A2BIN4_DANRE Isoform 1 of Splicing regulatory glutamine/lysine-rich protein 1 OS=Danio rerio OX=7955 GN=srek1 PE=3 SV=1 CANONICAL=A2BIN4-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BCX1-1", "url": "https://www.uniprot.org/uniprotkb/A2BIN4/entry#A0A8M2BCX1-1", "sequence": { "sequence": "MSGMPGTNVIQITNLSAAVSSDQMRTLFGFLGDIDELRLYPPDNAPLSFSSKVCYIKYREPSSVGVAQHLTNTVFIDRALIVVPCAEGKIPEEAKALSLLAPATPVASLMSGGGLLPIPSPSTLQNRSLPLANLGVLKSSLDTSVATLSAVSAQPPLMGNVDPSKVDEIRRTVYVGNLNSQSTTADQLLKFFKQVGDVKFVRMAGDETQPTRFAFVEFADQDSVARALTYNGVMFGDRPLKINHSNNAIVKPPELTPQAAAKELEDVMKKVREAQSTIAAAIEPENELPSSSRSRHSRRSRSHSCSPSNSRRKRSRSRHRGHPSKRSRQRFNDSCGSHRRHSRSRERRRSQSRSHSRGRRKDKDSKGRKDDDWDEKRLRDKTGRSPPKCYVGSRRSRSTSRGKREKKREKGWDSSRERAESSAFRRKSRDSEYKAKPSQRERVYEQMEHEYDSEMDGSGSMVSDDRSPPAHLNGSYRSSYAEEDNLFAAE", "length": 490, "header": "tr|A0A8M2BCX1-1|A2BIN4_DANRE Computationally mapped isoform of Splicing regulatory glutamine/lysine-rich protein 1 OS=Danio rerio OX=7955 GN=srek1 PE=3 SV=1 CANONICAL=A2BIN4-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q8F0-1", "url": "https://www.uniprot.org/uniprotkb/A2BIN4/entry#A0A8M9Q8F0-1", "sequence": { "sequence": "MSGMPGTNVIQITNLSAAVSSDQMRTLFGFLGDIDELRLYPPDNAPLSFSSKVCYIKYREPSSVGVAQHLTNTVFIDRALIVVPCAEGKIPEEAKALSLLAPATPVASLMSGGGLLPIPSPSTLQNRSLPLANLGVLKSSLDTSVATLSAVSAQPPLMGNVDPSKVDEIRRTVYVGNLNSQSTTADQLLKFFKQVGDVKFVRMAGDETQPTRFAFVEFADQDSVARALTYNGVMFGDRPLKINHSNNAIVKPPELTPQAAAKELEDVMKKVREAQSTIAAAIEPENELPSSSRSRHSRRSRSHSCSPSNSRRKRSRSRHRGHPSKRSRQRFNDSCGSHRRHSRSRERRRSQSRSHSRGRRKDKDSKGRKDDDWDEKRLRDKTGRSPPKCYVGSRRSRSTSRGHKKRSRSPSRSPRQRARGKREKKREKGWDSSRERAESSAFRRKSRDSEYKAKPSQRERVYEQMEHEYDSEMDGSGSMVSDDRSPPAHLNGSYRSSYAEEDNLFAAE", "length": 508, "header": "tr|A0A8M9Q8F0-1|A2BIN4_DANRE Computationally mapped isoform of Splicing regulatory glutamine/lysine-rich protein 1 OS=Danio rerio OX=7955 GN=srek1 PE=3 SV=1 CANONICAL=A2BIN4-1" }, "locus": {} }, { "isoform_ac": "A0AC58JIC7-1", "url": "https://www.uniprot.org/uniprotkb/A2BIN4/entry#A0AC58JIC7-1", "sequence": { "sequence": "MVHDQYVSSTGKIPEEAKALSLLAPATPVASLMSGGGLLPIPSPSTLQNRSLPLANLGVLKSSLDTSVATLSAVSAQPPLMGNVDPSKVDEIRRTVYVGNLNSQSTTADQLLKFFKQVGDVKFVRMAGDETQPTRFAFVEFADQDSVARALTYNGVMFGDRPLKINHSNNAIVKPPELTPQAAAKELEDVMKKVREAQSTIAAAIEPENELPSSSRSRHSRRSRSHSCSPSNSRRKRSRSRHRGHPSKRSRQRFNDSCGSHRRHSRSRERRRSQSRSHSRGRRKDKDSKGRKDDDWDEKRLRDKTGRSPPKCYVGSRRSRSTSRGHKKRSRSPSRSPRQRARGKREKKREKGWDSSRERAESSAFRRKSRDSEYKAKPSQRERVYEQMEHEYDSEMDGSGSMVSDDRSPPAHLNGSYRSSYAEEDNLFAAE", "length": 431, "header": "tr|A0AC58JIC7-1|A0AC58JIC7_DANRE Computationally mapped isoform of Splicing regulatory glutamine/lysine-rich protein 1 OS=Danio rerio OX=7955 GN=srek1 PE=3 SV=1 CANONICAL=A2BIN4-1" }, "locus": {} }, { "isoform_ac": "A0AC58JIC9-1", "url": "https://www.uniprot.org/uniprotkb/A2BIN4/entry#A0AC58JIC9-1", "sequence": { "sequence": "MVHDQYVSSTGKIPEEAKALSLLAPATPVASLMSGGGLLPIPSPSTLQNRSLPLANLGVLKSSLDTSVATLSAVSAQPPLMGNVDPSKVDEIRRTVYVGNLNSQSTTADQLLKFFKQVGDVKFVRMAGDETQPTRFAFVEFADQDSVARALTYNGVMFGDRPLKINHSNNAIVKPPELTPQAAAKELEDVMKKVREAQSTIAAAIEPENELPSSSRSRHSRRSRSHSCSPSNSRRKRSRSRHRGHPSKRSRQRFNDSCGSHRRHSRSRERRRSQSRSHSRGRRKDKDSKGRKDDDWDEKRLRDKTGRSPPKCYVGSRRSRSTSRGHKKRSRSPSRSPRQRARSPTPTKRGKREKKREKGWDSSRERAESSAFRRKSRDSEYKAKPSQRERVYEQMEHEYDSEMDGSGSMVSDDRSPPAHLNGSYRSSYAEEDNLFAAE", "length": 438, "header": "tr|A0AC58JIC9-1|A0AC58JIC9_DANRE Computationally mapped isoform of Splicing regulatory glutamine/lysine-rich protein 1 OS=Danio rerio OX=7955 GN=srek1 PE=3 SV=1 CANONICAL=A2BIN4-1" }, "locus": {} }, { "isoform_ac": "A0AC58JIE2-1", "url": "https://www.uniprot.org/uniprotkb/A2BIN4/entry#A0AC58JIE2-1", "sequence": { "sequence": "MSGGGLLPIPSPSTLQNRSLPLANLGVLKSSLDTSVATLSAVSAQPPLMGNVDPSKVDEIRRTVYVGNLNSQSTTADQLLKFFKQVGDVKFVRMAGDETQPTRFAFVEFADQDSVARALTYNGVMFGDRPLKINHSNNAIVKPPELTPQAAAKELEDVMKKVREAQSTIAAAIEPENELPSSSRSRHSRRSRSHSCSPSNSRRKRSRSRHRGHPSKRSRQRFNDSCGSHRRHSRSRERRRSQSRSHSRGRRKDKDSKGRKDDDWDEKRLRDKTGRSPPKCYVGSRRSRSTSRGKREKKREKGWDSSRERAESSAFRRKSRDSEYKAKPSQRERVYEQMEHEYDSEMDGSGSMVSDDRSPPAHLNGSYRSSYAEEDNLFAAE", "length": 381, "header": "tr|A0AC58JIE2-1|A0AC58JIE2_DANRE Computationally mapped isoform of Splicing regulatory glutamine/lysine-rich protein 1 OS=Danio rerio OX=7955 GN=srek1 PE=3 SV=1 CANONICAL=A2BIN4-1" }, "locus": {} }, { "isoform_ac": "A0AC58JIF1-1", "url": "https://www.uniprot.org/uniprotkb/A2BIN4/entry#A0AC58JIF1-1", "sequence": { "sequence": "MSGGGLLPIPSPSTLQNRSLPLANLGVLKSSLDTSVATLSAVSAQPPLMGNVDPSKVDEIRRTVYVGNLNSQSTTADQLLKFFKQVGDVKFVRMAGDETQPTRFAFVEFADQDSVARALTYNGVMFGDRPLKINHSNNAIVKPPELTPQAAAKELEDVMKKVREAQSTIAAAIEPENELPSSSRSRHSRRSRSHSCSPSNSRRKRSRSRHRGHPSKRSRQRFNDSCGSHRRHSRSRERRRSQSRSHSRGRRKDKDSKGRKDDDWDEKRLRDKTGRSPPKCYVGSRRSRSTSRGHKKRSRSPSRSPRQRARSPTPTKRGKREKKREKGWDSSRERAESSAFRRKSRDSEYKAKPSQRERVYEQMEHEYDSEMDGSGSMVSDDRSPPAHLNGSYRSSYAEEDNLFAAE", "length": 406, "header": "tr|A0AC58JIF1-1|A0AC58JIF1_DANRE Computationally mapped isoform of Splicing regulatory glutamine/lysine-rich protein 1 OS=Danio rerio OX=7955 GN=srek1 PE=3 SV=1 CANONICAL=A2BIN4-1" }, "locus": {} }, { "isoform_ac": "A0AC58JIF2-1", "url": "https://www.uniprot.org/uniprotkb/A2BIN4/entry#A0AC58JIF2-1", "sequence": { "sequence": "MVHDQYVSSTGKIPEEAKALSLLAPATPVASLMSGGGLLPIPSPSTLQNRSLPLANLGVLKSSLDTSVATLSAVSAQPPLMGNVDPSKVDEIRRTVYVGNLNSQSTTADQLLKFFKQVGDVKFVRMAGDETQPTRFAFVEFADQDSVARALTYNGVMFGDRPLKINHSNNAIVKPPELTPQAAAKELEDVMKKVREAQSTIAAAIEPENELPSSSRSRHSRRSRSHSCSPSNSRRKRSRSRHRGHPSKRSRQRFNDSCGSHRRHSRSRERRRSQSRSHSRGRRKDKDSKGRKDDDWDEKRLRDKTGRSPPKCYVGSRRSRSTSRGKREKKREKGWDSSRERAESSAFRRKSRDSEYKAKPSQRERVYEQMEHEYDSEMDGSGSMVSDDRSPPAHLNGSYRSSYAEEDNLFAAE", "length": 413, "header": "tr|A0AC58JIF2-1|A0AC58JIF2_DANRE Computationally mapped isoform of Splicing regulatory glutamine/lysine-rich protein 1 OS=Danio rerio OX=7955 GN=srek1 PE=3 SV=1 CANONICAL=A2BIN4-1" }, "locus": {} }, { "isoform_ac": "A2BIN4-1", "url": "https://www.uniprot.org/uniprotkb/A2BIN4/entry#A2BIN4-1", "sequence": { "sequence": "MSGMPGTNVIQITNLSAAVSSDQMRTLFGFLGDIDELRLYPPDNAPLSFSSKVCYIKYREPSSVGVAQHLTNTVFIDRALIVVPCAEGKIPEEAKALSLLAPATPVASLMSGGGLLPIPSPSTLQNRSLPLANLGVLKSSLDTSVATLSAVSAQPPLMGNVDPSKVDEIRRTVYVGNLNSQSTTADQLLKFFKQVGDVKFVRMAGDETQPTRFAFVEFADQDSVARALTYNGVMFGDRPLKINHSNNAIVKPPELTPQAAAKELEDVMKKVREAQSTIAAAIEPENELPSSSRSRHSRRSRSHSCSPSNSRRKRSRSRHRGHPSKRSRQRFNDSCGSHRRHSRSRERRRSQSRSHSRGRRKDKDSKGRKDDDWDEKRLRDKTGRSPPKCYVGSRRSRSTSRGHKKRSRSPSRSPRQRARSPTPTKRGKREKKREKGWDSSRERAESSAFRRKSRDSEYKAKPSQRERVYEQMEHEYDSEMDGSGSMVSDDRSPPAHLNGSYRSSYAEEDNLFAAE", "length": 515, "header": "tr|A2BIN4-1|A2BIN4_DANRE Isoform 1 of Splicing regulatory glutamine/lysine-rich protein 1 OS=Danio rerio OX=7955 GN=srek1 PE=3 SV=1 CANONICAL=A2BIN4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Hematopoietic gene expression profile in zebrafish kidney marrow.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2004", "authors": "Song Huai-Dong, Sun Xiao-Jian, Deng Min, Zhang Guo-Wei, Zhou Yi, Wu Xin-Yan, Sheng Yan, Chen Yi, Ruan Zheng, Jiang Chun-Lei, Fan Hui-Yong, Zon Leonard I, Kanki John P, Liu Ting Xi, Look A Thomas, Chen Zhu", "evidence": [ { "database": "UniProtKB", "id": "A2BIN4", "url": "https://www.uniprot.org/uniprotkb/A2BIN4" } ], "reference": [ { "type": "PubMed", "id": "15520368", "url": "https://glygen.org/publication/PubMed/15520368" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A2BIN4", "url": "https://www.uniprot.org/uniprotkb/A2BIN4" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:445219", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:445219", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B859-1", "protein_name": "Splicing regulatory glutamine/lysine-rich protein 1", "gene_name": "SREK1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNSGGGFGLGLGFGLTPTAVIQVTNLSSAVTSEQMRTLFSFLGEIEELRLYPPDNAPLAFSSKVCYVKFRDPSSVGVAQHLTNTVFIDRALIVVPCAEGKIPEEAKALSLLAPAPTMTGLMPGAGLLPIPTPNPLTTLGVSLSSLGAIPAAALDPNIATLGEIPQPPLMGNVDPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSRSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSRSRDKRKDTREKIKEKERVKEKDREKEREKERDREKEREKEKERGKNKDKDRDKEREKDRDKDKEKDRDREREKEHEKERDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSTRKSSNDRDGKEKAEKNSTSLKEKEHNKEPDSNVGKEVDDKDPPPRTEENKVQQNGNCQPNEENLSTKTEAV", "length": 631 }, "evidence": [ { "id": "A2BIN4", "url": "https://omabrowser.org/oma/group/A2BIN4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Y813-1", "protein_name": "Splicing regulatory glutamine/lysine-rich protein 1", "gene_name": "SREK1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MMNSGGIGVPLGFPLGPTSVIQVTNLSSAVTSEQMRTLFGFLGDIEELRLYPPDNAPLAFSSKVCYIKFREASSVGVAQHLTNTVFIDRALIVVPCAEGKIPDEAKALSLLAPAPTMTSLMPGAGLLPIPTPTPLTTLGVSLGTLGAIPAAALDPNITALGEIPQPPIMGNVDPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSSERKGGRSRSHSRSESRSSSKSRSRRKRSHSKHRSRSGNRSLSRHKDRRRSRSPLKKRSRSRERRKSRSRSRSRDKKRDKEKVKEKEKTKEKERDRDKEKERDRDRDKEREREREKERNRDKDREKDKDRNKDRERVKDRDRDRDKEREKEKDEKEKDREDVDQNKEKDDDRDGERDREKMKDREGDKDKGGDKEKDREKEKEKDGDKEREREKERDDKKKKDKRSRTPPRSYSSSRRSRSSSRERRKRKSRSLSKSPKTSKGTKRKSSRTPSPRRNKKEKKRERDTCNEGRERERSTSKKKSSKEKEGREKSDKSTTTLKDKDHAKEDQNSETDKDVDNRDTQRTDEVKLQQNGNCQPNEDNLSIKMEEV", "length": 671 }, "evidence": [ { "id": "A2BIN4", "url": "https://omabrowser.org/oma/group/A2BIN4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BDN8-1", "protein_name": "Splicing regulatory glutamine/lysine-rich protein 1", "gene_name": "SREK1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNSAGSFGLGLGFGLTPTAVIQVTNLSSAVTSEQMRTLFSFLGEIEELRLYPPDNAPLAFSSKVCYVKFRDPSSVGVAQHLTNTVFIDRALIVVPCAEGKIPEEAKALSLLAPAPTMTSLMPGAGLLPIPTPNPLTTLGVSLSSLGAIPAAALDPNIATLGEIPQPPLMGNVDPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSRSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSRSRDKRKDTREKIKEKERVKEKDREKEREKERDREKEREKEKERGKNKDKDRDKEREKDRDKDKDKEKDKERERDKDHEKERDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKEKDHISERRERERSASTRKSSNDREGKDKVEKNNTSLKEKEHNKEPDSSVGKEVDDKDAPRTEENKVQQNGNCQPNEENLSAKTEAV", "length": 632 }, "evidence": [ { "id": "A2BIN4", "url": "https://omabrowser.org/oma/group/A2BIN4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3H4M8-1", "protein_name": "Splicing regulatory glutamine/lysine-rich protein 1", "gene_name": "Srek1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MNSGGGFGLGLGFGLFPTAVIQVTNLSSAVTSEQMRTLFSFLGDIEELRLYPPDNTPLAFSSKVCYIKFRDPSSVGVAQHLTNTVFIDRALIVVPCAEGKIPEEAKALSLLAPAPTMTSLVPGAGLLPIPTSSPLTAVSSLGVSLSSLGAIPAAALDPNITTLGEIPQPPLMGNVDPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSRSRDKRKDTREKVKEKERVKEREREKEKEREREKDREKDKERGKNKDKDREKEKDHEKERDKDKEKDQDKDKEREKDKSKEADEKRKKDKKSRTPPRSYNASRRSRSTSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRGRNKKDKKREKERDHISDRRERERSTSTKKSSNDGKEKVEKTNTPVKKEHSKEADSSVSQDTDEKDPPRTEEENKVQQNGNCQPSEESLCSKADVV", "length": 611 }, "evidence": [ { "id": "A2BIN4", "url": "https://omabrowser.org/oma/group/A2BIN4/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BZX4-1", "protein_name": "Splicing regulatory glutamine/lysine-rich protein 1", "gene_name": "Srek1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLVPGAGLLPIPTSSPLTAVSSLGVSLSSLGAIPAAALDPNITTLGEIPQPPLMGNVDPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSRSRDKRKDTREKVKERVKEKEREKEREREKDREKDKERGKNKDKDREKEKDHEKERDKEKEKEQDKDKEREKDRSKETDEKRKKEKKSRTPPRSYNASRRSRSTSRERRRRRSRSSSRSPRTSKTVKRKSSRSPSPRGRNKKEKKREKERDHISDRRERERSTSTKKSSGDRDGKEKVEKSTTPVKEKEHSKESDATVSKAADEKGSPRTEDEGKVQHNGNCQPNEESPCSKADAV", "length": 494 }, "evidence": [ { "id": "MGI:2145245", "url": "https://alliancegenome.org/gene/MGI:2145245#orthology", "database": "AGR" }, { "id": "HGNC:17882", "url": "https://alliancegenome.org/gene/HGNC:17882#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-132#orthology", "database": "AGR" }, { "id": "A2BIN4", "url": "https://omabrowser.org/oma/group/A2BIN4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WXA9-1", "protein_name": "Splicing regulatory glutamine/lysine-rich protein 1", "gene_name": "SREK1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSLMPGAGLLPIPTPNPLTTLGVSLSSLGAIPAAALDPNIATLGEIPQPPLMGNVDPSKIDEIRRTVYVGNLNSQTTTADQLLEFFKQVGEVKFVRMAGDETQPTRFAFVEFADQNSVPRALAFNGVMFGDRPLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQLNEENLSTKTEAV", "length": 508 }, "evidence": [ { "id": "MGI:2145245", "url": "https://alliancegenome.org/gene/MGI:2145245#orthology", "database": "AGR" }, { "id": "HGNC:17882", "url": "https://alliancegenome.org/gene/HGNC:17882#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040801-132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-132#orthology", "database": "AGR" }, { "id": "A2BIN4", "url": "https://omabrowser.org/oma/group/A2BIN4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JKL7-1", "protein_name": "Splicing regulatory glutamine/lysine-rich protein 1", "gene_name": "Srek1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PMX5-1", "uniprot_ac": "A0A8M9PMX5", "uniprot_id": "A0A8M9PMX5_DANRE", "mass": { "chemical_mass": 241966.0, "monoisotopic_mass": 241966.0 }, "refseq": { "ac": "XP_021332847", "name": "dedicator of cytokinesis protein 7 isoform X9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332847" }, "gene_names": [ { "name": "dock7", "type": "recommended", "evidence": [ { "id": "A0A8M9PMX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5" } ] }, { "name": "dock7", "type": "synonym", "evidence": [ { "id": "XP_021332847", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332847" } ] } ], "protein_names": [ { "name": "Dedicator of cytokinesis protein 7 isoform X9", "type": "synonym", "evidence": [ { "id": "A0A8M9PMX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#names_and_taxonomy" } ] }, { "name": "dedicator of cytokinesis protein 7 isoform X9", "type": "synonym", "evidence": [ { "id": "XP_021332847", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332847" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021332847", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332847" } ] } ], "disease": [ { "disease_id": "DOID:0080415", "recommended_name": { "id": "DOID:0080415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080415", "name": "developmental and epileptic encephalopathy 23", "description": "A developmental and epileptic encephalopathy characterized by onset in the first months of life of intractable seizures, severely impaired psychomotor development with poor or absent speech, cortical blindness, and dysmorphic facial features that has_material_basis_in homozygous or compound heterozygous mutation in the DOCK7 gene on chromosome 1p31." }, "synonyms": [ { "id": "DOID:0080415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080415", "name": "Early-onset epileptic encephalopathy-cortical blindness-intellectual disability-facial dysmorphism syndrome", "description": "" }, { "id": "DOID:0080415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080415", "name": "Epilepsy-cortical blindness-intellectual disability-facial dysmorphism syndrome", "description": "" }, { "id": "DOID:0080415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080415", "name": "DEE23", "description": "" }, { "id": "DOID:0080415", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080415", "name": "early infantile epileptic encephalopathy 23", "description": "" }, { "id": "MONDO:0014371", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014371", "name": "developmental and epileptic encephalopathy, 23", "description": "" }, { "id": "MONDO:0014371", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014371", "name": "EIEE23", "description": "" }, { "id": "MONDO:0014371", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014371", "name": "developmental and epileptic encephalopathy 23", "description": "" }, { "id": "MONDO:0014371", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014371", "name": "developmental and epileptic encephalopathy, 23", "description": "" }, { "id": "MONDO:0014371", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014371", "name": "early-onset epileptic encephalopathy-cortical blindness-intellectual disability-facial dysmorphism syndrome", "description": "" }, { "id": "MONDO:0014371", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014371", "name": "epilepsy-cortical blindness-intellectual disability-facial dysmorphism syndrome", "description": "" }, { "id": "MONDO:0014371", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014371", "name": "epileptic encephalopathy, early infantile, 23", "description": "" }, { "id": "MONDO:0014371", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014371", "name": "epileptic encephalopathy, early infantile, type 23", "description": "" }, { "id": "MIM:615859", "resource": "MIM", "url": "https://www.omim.org/entry/615859", "name": "Developmental and epileptic encephalopathy 23", "description": "Developmental and epileptic encephalopathy 23" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080415", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080415" } ] }, { "disease_id": "DOID:2223", "recommended_name": { "id": "DOID:2223", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2223", "name": "platelet storage pool deficiency", "description": "" }, "synonyms": [ { "id": "DOID:2223", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2223", "name": "Dense body defect", "description": "" }, { "id": "DOID:2223", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2223", "name": "Platelet dense granule deficiency", "description": "" }, { "id": "DOID:2223", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2223", "name": "Platelet storage pool defect", "description": "" }, { "id": "MONDO:0008495", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008495", "name": "platelet storage pool deficiency", "description": "Platelet storage pool deficiency refers to a group of conditions that are caused by problems with the platelet granules. Platelet granules are tiny storage sacs found within the platelets which release various substances to help stop bleeding. Platelet storage pool deficiencies occur when platelet granules are absent, reduced in number, or unable to empty their contents into the bloodstream. The signs and symptoms include frequent nosebleeds; abnormally heavy or prolonged menstruation ; easy bruising; recurrent anemia ; and abnormal bleeding after surgery, dental work or childbirth. Platelet storage pool deficiencies may be genetic or acquired (non-genetic). They can also be part of an inherited genetic syndrome such as Hermansky-Pudlak syndrome, Chediak-Higashi syndrome, thrombocytopenia-absent radius (TAR) syndrome, and Wiskott-Aldrich syndrome. 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"https://www.uniprot.org/uniprotkb/A0A8M9Q6X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q6Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q6Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q6Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q6Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q6Y7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q6Y7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q6Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q6Y7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QB50", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QB50", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QB50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QB50-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QG48", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QG48", 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}, { "id": "A0AC58JV62", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV62-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV64", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV64-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV67", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV67-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV77", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV77-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV81", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV81-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV83", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV83-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV85", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV85-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV87", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV87-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV89", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV89-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV90", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV90-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV92", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV92-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV93", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV93-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV94", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV94-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV95", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV95", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV95-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV95-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV97", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JV97-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JV97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVA5", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVA5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVA8", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVA8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVA8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVA8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVA9", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVA9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVB7", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVB7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVC0", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVC0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVC0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVC0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVC2", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVC2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVE6", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVE6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q8Z1", "url": "https://www.uniprot.org/uniprotkb/F1Q8Z1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q8Z1-1", "url": "https://www.uniprot.org/uniprotkb/F1Q8Z1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050302-15", "url": "https://zfin.org/ZDB-GENE-050302-15", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2131, "header": "tr|A0A8M9PMX5-1|A0A8M9PMX5_DANRE Isoform 1 of Dedicator of cytokinesis protein 7 isoform X9 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BD70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0A8M2BD70-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2125, "header": "tr|A0A8M2BD70-1|A0A8M9PMX5_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X9 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PMX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0A8M9PMX0-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2138, "header": "tr|A0A8M9PMX0-1|A0A8M9PMX0_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X3 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PMX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0A8M9PMX5-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2131, "header": "tr|A0A8M9PMX5-1|A0A8M9PMX5_DANRE Isoform 1 of Dedicator of cytokinesis protein 7 isoform X9 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q0M5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0A8M9Q0M5-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2137, "header": "tr|A0A8M9Q0M5-1|A0A8M9PMX5_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X9 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q6X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0A8M9Q6X7-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2144, "header": "tr|A0A8M9Q6X7-1|A0A8M9PMX5_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X9 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q6Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0A8M9Q6Y2-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2136, "header": "tr|A0A8M9Q6Y2-1|A0A8M9PMX5_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X9 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q6Y7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0A8M9Q6Y7-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2113, "header": "tr|A0A8M9Q6Y7-1|A0A8M9PMX5_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X9 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9QB50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0A8M9QB50-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2083, "header": "tr|A0A8M9QB50-1|A0A8M9PMX5_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X9 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9QG48-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0A8M9QG48-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2142, "header": "tr|A0A8M9QG48-1|A0A8M9PMX5_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X9 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9QG53-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0A8M9QG53-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHSKRTA", "length": 2135, "header": "tr|A0A8M9QG53-1|A0A8M9PMX5_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X9 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AB32TU39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AB32TU39-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHSKRTA", "length": 2133, "header": "tr|A0AB32TU39-1|A0A8M9PMX5_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X9 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AB32TVU4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AB32TVU4-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2068, "header": "tr|A0AB32TVU4-1|A0A8M9PMX5_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X9 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV62-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHSKRTA", "length": 2120, "header": "tr|A0AC58JV62-1|A0AC58JV62_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X14 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV64-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV64-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHSKRTA", "length": 2127, "header": "tr|A0AC58JV64-1|A0AC58JV64_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X11 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV67-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV67-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2135, "header": "tr|A0AC58JV67-1|A0AC58JV67_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X6 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV77-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2107, "header": "tr|A0AC58JV77-1|A0AC58JV77_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X17 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV81-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2106, "header": "tr|A0AC58JV81-1|A0AC58JV81_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X18 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV83-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV83-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2076, "header": "tr|A0AC58JV83-1|A0AC58JV83_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X28 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV85-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHSKRTA", "length": 2096, "header": "tr|A0AC58JV85-1|A0AC58JV85_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X23 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV87-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2077, "header": "tr|A0AC58JV87-1|A0AC58JV87_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X27 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV89-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV89-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2074, "header": "tr|A0AC58JV89-1|A0AC58JV89_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X30 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV90-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHSKRTA", "length": 2095, "header": "tr|A0AC58JV90-1|A0AC58JV90_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X24 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV92-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2105, "header": "tr|A0AC58JV92-1|A0AC58JV92_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X19 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV93-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHSKRTA", "length": 2126, "header": "tr|A0AC58JV93-1|A0AC58JV93_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X12 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV94-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2098, "header": "tr|A0AC58JV94-1|A0AC58JV94_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X22 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV95-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV95-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHSKRTA", "length": 2066, "header": "tr|A0AC58JV95-1|A0AC58JV95_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X33 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JV97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JV97-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHSKRTA", "length": 2065, "header": "tr|A0AC58JV97-1|A0AC58JV97_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X34 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JVA5-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2111, "header": "tr|A0AC58JVA5-1|A0AC58JVA5_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X16 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JVA8-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKAHFLFMQGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2075, "header": "tr|A0AC58JVA8-1|A0AC58JVA8_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X29 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JVA9-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHSKRTA", "length": 2059, "header": "tr|A0AC58JVA9-1|A0AC58JVA9_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X35 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JVB7-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2100, "header": "tr|A0AC58JVB7-1|A0AC58JVB7_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X21 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVC0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JVC0-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHSKRTA", "length": 2089, "header": "tr|A0AC58JVC0-1|A0AC58JVC0_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X25 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVC2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JVC2-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQSTGWERMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2070, "header": "tr|A0AC58JVC2-1|A0AC58JVC2_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X31 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#A0AC58JVE6-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKGQRSVRTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2104, "header": "tr|A0AC58JVE6-1|A0AC58JVE6_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X20 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} }, { "isoform_ac": "F1Q8Z1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5/entry#F1Q8Z1-1", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQIAGQYGGSPQLLKNLSVGGNATSNAIPLTEAVEPVDFEEYLITHPPIIESGPLRDLIEFPPDDIEVLYTPRECRTLSQAVPEEGENDPHVRDCTRSYTEDWAIVNRKYHKLGTAFNPNTLDKQKERQRGLPKQVFESDELPDQSSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSQPDALLPHLLDRVPNEEIDRHNEDLRKSNRHRELFALHPALDEEEPIERHCVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFATLALYDVKEKKKISENFYFDLNSEQTKGMLRPHIPSAAISTLARSAVFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMVFKESDAAKNKEKLEKLRSQAEQFCQRLGRYRMPFAWTAIHLMNIVNSAGSLERDTEVDMGLSERKGSWSERRNSSIVGRRSLERTTSGDESCSLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPDLLQVKPYPDSRVRPTKEILEFPARDVYVPNTTYRNLLYVNPQSLNFANRQGSARNITVKVQFMNGEDPSNAMPVISGKSSCAEFSKEAYTSVVYHNRSPDFYDEVKIKLPASLTDHHHILFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLRTGHFCLPVSLEKPPQSYSVLSPDVPLPGMKWVDNHRGVFNVEVVAASTIHTQDQYLDKFFALVHALDEHMFPVRIGDMRIMENNLETELKSSIAALNSSQLEPVVRFLHLLLDKLVLLMVRPPVIAGQIVNLGQASFEVMASIVNRLHKYLDTSQDMHGRNSLLSSYIHYVFRLPNMDPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVHTMGCKSAPWGTSPGSTSDTKQAMERSGNRMSSHTESASFLQTLTGRLPTKKLFHEELALQWVVSSGSVREGALQQAWFFFELMVKSIIHHLYFTDRLESPRKNRFPERFMDDITALVSTIAGDIVSRFQKDLELVERLNTSLAFFLNDLLSVMDRGFVFTLIKTYWKQVSTKLYALQNPTLESLRLDFLRIVCSHEHYVTLNLPFSLLTPPASPSPSVSSATSQSSGFSTHVQDQKIANMFELSVPFREQHYLAGLILTELAVILEPEADGSVPWMFGLHKKVISVVHNLLSSHDSDPRYADPEVKARVALLYLPLIGIVMETLPQLHDFTESLNQWGRGGPGTEEQEAEGNSMISQTVAMAIAGTSVPQMSRPSSFLLNPQATRQHGSFSAESSRSLLICLLWVLKNADEMVLQKWFTDLSVSQLNRLLDLLYLCVSCFEYKGKKAFERMNSLTFKKSKDMKAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQTSEKMDKTRAELEHEAIIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLHSMACNQSALYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRNCSSSIGTIRAHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERNNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTEAGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLATIHGKLQEAFGKIVHQDGKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLAEISHRLESFYGERFGEDQVEVIKDSNPVDKCKLDPNKAFIQITYVEPYFDTYEMKDRITYFDKNYNLRRFVYCTPFTLDGRAHGDLHEQFKRKTILTTSHAFPYIKTRINIIHKEEIISTPIEVAIEDMQKKTQELAFATHQDPSDAKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLYRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKPVLQVNSHRDSFSRMSLRKLDM", "length": 2129, "header": "tr|F1Q8Z1-1|F1Q8Z1_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 7 isoform X10 OS=Danio rerio OX=7955 GN=dock7 PE=1 SV=1 CANONICAL=A0A8M9PMX5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:568817", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568817", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KAH4-1", "protein_name": "Dedicator of cytokinesis 6", "gene_name": "Dock6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRSSSSLGVPLTEVIEPLDFEDVLLSRPPEVEPGPLRDMIEFPADDLELLKQPRECRTTESGVPEDGKLDAQVRAAVEMYSEDWVIVRRRYQHLSTAYSPITTETQRERQKGLTCQVFEQDTPGDERTGPEDVDDSQHCSGSPEDTPRSSGASGVFSLRNLAADSLLPTLLERAAPEDVDRRNEALRRQHRAPALLTLYPAPDEDEAVERCSHPEPPREHFGQRILVKCLSLKFEIEIEPIFGTLALYDVREKKKISENFYFDLNSDSVKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVVKLEKVLQQGDISECCEPYMVMKEADTVKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSVGPQDRDSDSEGERRPTWAERRRRGPQDRSYSGDDACSFSSFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKIDISPAPENLHFCLSPELLHVKPYPDPRGRPTKEILEFPAREVYAPHTCYRNLLFVYPHSLNFSSRQGSVRNLAVRIQYMAGEDQSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLRLPACVTENHHLFFTFYHVSCQPRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQDPHLDKFFTLVHVLEEGIFPFRLKETVLSEGTMEQELRASLAALRLASPEPLVAFSHHVLDKLVRLVVRPPVICGQMVNLGRGAFEAMAHVASLVHRNLEAVQDSRGHCPLLAAYVHYAFRLPGGDLGLPGEVPPATVQAATLARGSGRPASLYLARSKSISSSNPDLAVVPGSVDDEVSRILASKGVDRSHSWVNSAYAPGGSKAVLRRVPPYCGADPRQLLHEELALQWVVSGSAVRELVLQHAWFFFQLMVKSMELHLLLGQRLDTPRKLRFPGRFLDDIAALVASVGLEVITRVHKDMELAERLNASLAFFLSDLLSIADRGYIFSLVRAHYKQVATRLQSAPNPAALLTLRMDFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQSSTFSSQAPDPKVISMFELSGPFRQQHFLSGLLLTELALALDPEAEGASLLHKKAITAVHNLLCSHDVDSRYTDATVKAKVAELYLPLLSLARDTLPRLHGFAEGSGQRSRLASMLDSDTEGEGDIGGTINPSVAMAIAGGPLAPGSRTSISQGPSTAARSGCPLSAESSRTLLVCVLWVLKNAEPALLQRWAADLALPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKARLEEAILGTIGARQEMVRRSRERSPFGNQENVRWRKSVTHWRQTSDRVDKTKDEVEHEALVDGNLATEASLVVLDMLEIIVQTVMLSEARESILGAVLKVVLYSLGSAQSALFLQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLYLLMRQNFEIGHNFARVKMLVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDLGLRDSTFAEQVQDLMFNLHMILTDTVKMKEHQEDPEMLMDLMYRIARGYQGSPDLRLTWLQNMASKHAELGNHAEAAQCMVHAAALVAEYLALLEDSRHLPVGCVSFQNVSSNVLEESAISDDILSPDEEGFCSGKNFTDLGLVGLLEQAAAYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYGARFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKLKLDPQKAYIQITYVEPHFDTYELKDRVTYFDRNYGLRAFLFCTPFTPDGRAHGELAEQHKRKTLLSTEHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLSEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERHYSRLREALQPLLTQRLPQLLAPSSTSLRNSINRSSFRKTDL", "length": 2082 }, "evidence": [ { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A829-1", "protein_name": "Dedicator of cytokinesis 8", "gene_name": "Dock8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHARQALLPRAEIFFFFFNSRYSSSEIRKQFTLPPNLGQYHRHSLSTSGFPSLQLPQLYEPVEPVDFEGLVMTHLNSLDAELAQELGDLTDDDLHVAFTPKECRTLQHSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSPEFCSFRKTGSRRDFHKTLQKQTFESETLECSEPATQTGPRHRFNVLCDVSGKGPITSCDFDLRSLQPDERLENLLQLSAEDFEKEKEEARKTNRTAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKVLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVDPSSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIADCAEPYMIIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNVSTLERESTDLEPGAGRNSVGERRSLSQSRRPSERTLSFEENGVGSNFKTTTLATNIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGSLRLEIAPAPDVMNCCLTPEMLPVKPFPENRTRPHKEILEFPIREVYVPHTVYRNLLYVYPQRLNFANKLASARNITIKIQFMCGEDPSNAMPVIFGKSSGPEFLQEVYTAITYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGASGESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKITENTLEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLPELHRDAPKSGGPTAVVPDPRYHTYGRTSAAAVSSKLMQARVMSSSNPDLAGTHCAADEEVKNIMSSKIADRNCSRMSYYCSGNSDVPGSTAAPRPVSKKHFHEELALQMVVSTGLVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTSEIAALLVKPQKESEQAEKINISLAFFLYDLLSIMDRGFVFNLIKHYCTQLSAKLNTLPTLISMRLEFLRILCSHEHYLNLNLLFMNPDTAPASPCPSISSQNSSSCSSFQDQKIASMFDLTPEYRQQHFLTGLLFTELAVALDAEGDGISRVQRKAVSAIHSLLSSHDLDPRCLKPEVKVKIAALYLPLVGIILDALPQLYDFTDARSGRSRASGSYEEQDVANGINQNVALAIAGNHFNLKTSGAMLSSLPYKQYNMLNADTTRHLMVCFLWIMKNADQSLIRKWIADLPSMQLNRILDLLFICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRRRIPGTDRFPGLNENLRWRKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENIIQASSSLDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEMEQCADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMALASLVGKAPDFNEEHLRKSLRTILAYSEEDTAMRATLFPTQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKRKCFTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAFDNIINKDHKRMFGTYFRVGFYGSKFGDLDEQEFVYKEPAITKLPEISHRLEGFYGQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQHRRNTVLTTMHAFPYIKTRIRVSQKEEFVLTPIEVAIEDMKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELKKNYNRLKDSLRPMIERKIPELYKPIFRVDSQKRDSFHRSSFRKCETQLSQGS", "length": 2102 }, "evidence": [ { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACL2-1", "protein_name": "Dedicator of cytokinesis 7", "gene_name": "Dock7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDLEDYLITHPLAVDSGPLRDLVDFPPDDIEVVYSPRDCRTLVSAVPEESEMDPHVRDCIRSYTEDWAIVVRKYHKLGTGFNPNTLDKQKERQKGLPRQVFESDEAPDGNSYPDEQDDLKRRSMSIDDTPRGSWACSIFDLKNSLPDALLPNLLDRTPNEEIDHQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFASLALYDVKEKKKISENFYFDLNSEQMKGLLRPHVPPAAITTLARSAIFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSSAGSLERDSTEVEISTGERKGSWSERRNSSLVGRRSLERTASGDDACNLTSFRPATLTVANFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPELLQVKLYPDSRVRPTREILEFPARDVYVPNTTYRNLLYIYPQSLNFANRQGSARNITVKVQFMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEVKVKLPATLTDHHHLLFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEVPLPGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHMFPVRIGDMRIMENNLESELKSSISALNSSQLEPVVRFLHLLLDKLILLVVRPPVIAGQIVNLGQASFEAMASIINRLHKNLEGNHDQHGRNNLLASYIYYVFRLPNTYPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVNTGPKAAPWGSNPSPSAESTQAVDRSCNRMSSHTETSSFLQTLTGRLPTKKLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYFNDKLDAPRKSRFPERFMDDIAALVSTIAGDVVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFVFTLIKSCYKQVSAKLYSLPNPSVLVSLRLDFLRIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSLPFRQQHYLAGLVLTELALILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQIKARVAMLYLPLIGIIMETVPQLYDFTETHNQRGRPICIAPDDYDSESGSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTVTFSAESSRSLLICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYKGKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQNTEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLQSMACNQSAVYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRHCSSSISTIRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQSTGWERMFGTYFRVGFYGTKFGDLDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVLEVIKDSNPVDKCKLDPNKAYIQITYVEPFFDTYEMKDRITYFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPGDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKAVLPVTCHRDSFSRMSLRKMEL", "length": 2131 }, "evidence": [ { "id": "RGD:1309790", "url": "https://alliancegenome.org/gene/RGD:1309790#orthology", "database": "AGR" }, { "id": "HGNC:19190", "url": "https://alliancegenome.org/gene/HGNC:19190#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050302-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050302-15#orthology", "database": "AGR" }, { "id": "MGI:1914549", "url": "https://alliancegenome.org/gene/MGI:1914549#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" }, { "id": "A0A8M9PMX5", "url": "https://omabrowser.org/oma/group/A0A8M9PMX5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C147-1", "protein_name": "Dedicator of cytokinesis protein 8", "gene_name": "Dock8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATLPSAERRAFALKINRYSSSEIRKQFTLPPNLGQYHRHSISTSGFPSLQLPQLYEPVEPVDFEGLVMTHLNSLDAELAQELGDLTDDDLHVAFTPKECRTLQHSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSSEFCSFKKTGSRRDFQKTLQKQTFESETLECSEPDTQTGPRHPLNVLCDVSGKGPLTSCDFDLRSLQPDERLENLLQLVSAEDFEKEKEEARKTNRPAELFALYPPVDEEDAVEIRPVPECPKEHLGNRILVKVLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSIDPSSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIADCAEPYMIIKESDGGKSKEKVEKLKLQAESFCQRLGKYRMPFAWAPISLASFFNISTLERESTDVEPGVGRNSVGEKRSLSQSRRPSERTLSLEENGVGSNFKATTLATNIFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGSLRLEISPAPDVMNCCLTPEMLPVKPFPENRTRPHKEILEFPIREVYVPHTVYRNLLYVYPQRLNFASKLASARNITIKIQFMCGEDPSNAMPVIFGKSSGPEFLQEVYTAITYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGASGESLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSIHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVSFPIRVLDQKITESTLEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLRKDQHGRNCLLASYVHYVFRLPELHRDTSKSGGPTTVVPDPRYHTYGRTSAAAVSSKLMQARVMSSSNPDLTGSHCAADEEVKNIMSSKIADRNCSRMSYYCSGNSDAPGSTAAPRPVSKKHFHEELALQMVVSTGVVRETVFKYAWFFFELLVKSMAQYVHNLDKRDSFRRTRFSDRFKDDITTIVNVVTSEIAALLVKPQKESEQAEKINISLAFFLYDLLSIMDRGFVFNLIKHYCSQLSAKLNILPTLISMRLEFLRILCSHEHYLNLNLLFMNTDTAPASPCPSISSQNSSSCSSFQDQKIASMFDLTPEYRQQHFLTGLLFTELAVALDAEGDGISRVQRKAVSAIHSLLCSHDLDPRCRKPEVKVKIAALYLPLVGIILDALPQLYDFTDARSGRSRASGSYEEQDVANGINQNVALAIAGNHFNLKTSGAMLSSLPYKQYNMLNADTTRHLMICFLWIMKNADQSLIRKWIADLPSMQLNRILDLLFICVSCFEYKGKQSSDKVSNQVLQKSRDVKAKLEEALLRGEGARGEMMRRRIPGTDRFPGINENLRWRKEQTQWRQANEKLDKTKAELDQEALISGNLATEANLIILDMQENIIQASSALDCKDSLLGGVLRVLVNSLSCDQSTTYLTHCFATLRALIAKFGDLLFEEEMEQCADLCQRVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMALASLVGKAPDFNEEHLRRSLRTILAYSEEDTAMQTTPFPMQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCFTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESAVSDDTLSPDEDGVCSGRYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHRDFRKLTSTHDKLQKAFDNIINKDHKRMFGTYFRVGFYGSRFGDLDEQEFVYKEPAITKLPEISHRLEGFYGQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQHRRNTVLTTMHAFPYIKTRIRVSQKEEFVLTPIEVAIEDMKKKTLQLAVATHQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNRRLITAEQREYQQELKKNYNKLRDSLRPMIERKIPELYKPIFRVDSQKRDSFHRSSFRKCETQLSQGS", "length": 2100 }, "evidence": [ { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NF50-1", "protein_name": "Dedicator of cytokinesis protein 8", "gene_name": "DOCK8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATLPSAERRAFALKINRYSSAEIRKQFTLPPNLGQYHRQSISTSGFPSLQLPQFYDPVEPVDFEGLLMTHLNSLDVQLAQELGDFTDDDLDVVFTPKECRTLQPSLPEEGVELDPHVRDCVQTYIREWLIVNRKNQGSPEICGFKKTGSRKDFHKTLPKQTFESETLECSEPAAQAGPRHLNVLCDVSGKGPVTACDFDLRSLQPDKRLENLLQQVSAEDFEKQNEEARRTNRQAELFALYPSVDEEDAVEIRPVPECPKEHLGNRILVKLLTLKFEIEIEPLFASIALYDVKERKKISENFHCDLNSDQFKGFLRAHTPSVAASSQARSAVFSVTYPSSDIYLVVKIEKVLQQGEIGDCAEPYTVIKESDGGKSKEKIEKLKLQAESFCQRLGKYRMPFAWAPISLSSFFNVSTLEREVTDVDSVVGRSSVGERRTLAQSRRLSERALSLEENGVGSNFKTSTLSVSSFFKQEGDRLSDEDLFKFLADYKRSSSLQRRVKSIPGLLRLEISTAPEIINCCLTPEMLPVKPFPENRTRPHKEILEFPTREVYVPHTVYRNLLYVYPQRLNFVNKLASARNITIKIQFMCGEDASNAMPVIFGKSSGPEFLQEVYTAVTYHNKSPDFYEEVKIKLPAKLTVNHHLLFTFYHISCQQKQGASVETLLGYSWLPILLNERLQTGSYCLPVALEKLPPNYSMHSAEKVPLQNPPIKWAEGHKGVFNIEVQAVSSVHTQDNHLEKFFTLCHSLESQVTFPIRVLDQKISEMALEHELKLSIICLNSSRLEPLVLFLHLVLDKLFQLSVQPMVIAGQTANFSQFAFESVVAIANSLHNSKDLSKDQHGRNCLLASYVHYVFRLPEVQRDVPKSGAPTALLDPRSYHTYGRTSAAAVSSKLLQARVMSSSNPDLAGTHSAADEEVKNIMSSKIADRNCSRMSYYCSGSSDAPSSPAAPRPASKKHFHEELALQMVVSTGMVRETVFKYAWFFFELLVKSMAQHVHNMDKRDSFRRTRFSDRFMDDITTIVNVVTSEIAALLVKPQKENEQAEKMNISLAFFLYDLLSLMDRGFVFNLIRHYCSQLSAKLSNLPTLISMRLEFLRILCSHEHYLNLNLFFMNADTAPTSPCPSISSQNSSSCSSFQDQKIASMFDLTSEYRQQHFLTGLLFTELAAALDAEGEGISKVQRKAVSAIHSLLSSHDLDPRCVKPEVKVKIAALYLPLVGIILDALPQLCDFTVADTRRYRTSGSDEEQEGAGAINQNVALAIAGNNFNLKTSGIVLSSLPYKQYNMLNADTTRNLMICFLWIMKNADQSLIRKWIADLPSTQLNRILDLLFICVLCFEYKGKQSSDKVSTQVLQKSRDVKARLEEALLRGEGARGEMMRRRAPGNDRFPGLNENLRWKKEQTHWRQANEKLDKTKAELDQEALISGNLATEAHLIILDMQENIIQASSALDCKDSLLGGVLRVLVNSLNCDQSTTYLTHCFATLRALIAKFGDLLFEEEVEQCFDLCHQVLHHCSSSMDVTRSQACATLYLLMRFSFGATSNFARVKMQVTMSLASLVGRAPDFNEEHLRRSLRTILAYSEEDTAMQMTPFPTQVEELLCNLNSILYDTVKMREFQEDPEMLMDLMYRIAKSYQASPDLRLTWLQNMAEKHTKKKCYTEAAMCLVHAAALVAEYLSMLEDHSYLPVGSVSFQNISSNVLEESVVSEDTLSPDEDGVCAGQYFTESGLVGLLEQAAELFSTGGLYETVNEVYKLVIPILEAHREFRKLTLTHSKLQRAFDSIVNKDHKRMFGTYFRVGFFGSKFGDLDEQEFVYKEPAITKLPEISHRLEAFYGQCFGAEFVEVIKDSTPVDKTKLDPNKAYIQITFVEPYFDEYEMKDRVTYFEKNFNLRRFMYTTPFTLEGRPRGELHEQYRRNTVLTTMHAFPYIKTRISVIQKEEFVLTPIEVAIEDMKKKTLQLAVAINQEPPDAKMLQMVLQGSVGATVNQGPLEVAQVFLAEIPADPKLYRHHNKLRLCFKEFIMRCGEAVEKNKRLITADQREYQQELKKNYNKLKENLRPMIERKIPELYKPIFRVESQKRDSFHRSSFRKCETQLSQGS", "length": 2099 }, "evidence": [ { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R1A4-1", "protein_name": "Dedicator of cytokinesis protein 7", "gene_name": "Dock7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDLEDYLVTHPLSGDSGPLRDLVEFPPDDIEVVYSPRDCRTLVSAVPEESEMDPHVRDCIRSYTEDWAVVVRKYHKLGTGFNPNTLDKQKERQKGLPRQVFESDEAPDGSSYQDEQDDLKRRSMSIDDTPRGSWACSIFDLKNSLPDALLPNLLDRTPNEEIDHQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDVPKEHFGQRLLVKCLSLKFEIEIEPIFASLALYDVKEKKKISENFYFDLNSEQMKGLLRPHVPPAAITTLARSAIFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSSAGSLERDSTEVEISTGERKGSWSERRNSSLVGRRSLERTTSGDDACNLTSFRPATLTVANFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPELLQVKLYPDSRVRPTREILEFPARDVYVPNTTYRNLLYIYPQSLNFANRQGSARNITVKVQFMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEVPLPGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHMFPVRIGDMRIMENNLESELKSSISALNSSQLEPVVRFLHLLLDKLILLVVRPPVIAGQIVNLGQASFEAMASIINRLHKNLEGNHDQHGRNNLLASYIYYVFRLPNTYPNSPSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVNTGPKAAPWGSNPSPSAESTQAMDRSCNRMSSHTETSSFLQTLTGRLPTKKLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYFNDKLDAPRESRFPERFMDDIAALVSTIAGDVVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFVFSLIKSCYKQVSAKLYSLPNPSVLVSLRLDFLRIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTSVQDQKIANMFELSLPFRQQHYLAGLVLTELALILDPDAEGLFGLHKKVINMVHNLLSTHDSDPRYSDPQIKARVAMLYLPLIGIIMETVPQLYDFTESHNQRGRPICIAPDDYDSESGSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTTFSAESSRSLLICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYKGKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQEMVRRSRGQLERSPSGSAFGSQENLRWRKDMTHWRQNSEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIIVQTVSVTESKESILGGVLKVLLQSMACNQSAVYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRHCSSSISTIRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQSTGWERMFGTYFRVGFYGTKFGDLDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVLEVIKDSNPVDKCKLDPNKAYIQITYVEPFFDTYEMKDRITYFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPGDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKAVLPVTCHRDSFSRMSLRKMEL", "length": 2130 }, "evidence": [ { "id": "RGD:1309790", "url": "https://alliancegenome.org/gene/RGD:1309790#orthology", "database": "AGR" }, { "id": "HGNC:19190", "url": "https://alliancegenome.org/gene/HGNC:19190#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050302-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050302-15#orthology", "database": "AGR" }, { "id": "MGI:1914549", "url": "https://alliancegenome.org/gene/MGI:1914549#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" }, { "id": "A0A8M9PMX5", "url": "https://omabrowser.org/oma/group/A0A8M9PMX5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8SAB7-1", "protein_name": "Guanine nucleotide exchange factor SPIKE 1", "gene_name": "SPK1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MENNNLGLRFRKLPRQPLALPKLDPLLDENLEQWPHLNQLVQCYGTEWVKDVNKYGHYENIRPDSFQTQIFEGPDTDTETEIRLASARSATIEEDVASISGRPFSDPGSSKHFGQPPLPAYEPAFDWENERAMIFGQRTPESPAASYSSGLKISVRVLSLAFQSGLVEPFFGSIALYNQERKEKLSEDFYFQIQPTEMQDAKLSSENRGVFYLDAPSASVCLLIQLEKTATEEGGVTSSVYSRKEPVHLTEREKQKLQVWSRIMPYRESFAWAVVPLFDNNLTTNTGESASPSSPLAPSMTASSSHDGVYEPIAKITSDGKQGYSGGSSVVVEISNLNKVKESYSEESIQDPKRKVHKPVKGVLRLEIEKHRNGHGDFEDLSENGSIINDSLDPTDRLSDLTLMKCPSSSSGGPRNGCSKWNSEDAKDVSRNLTSSCGTPDLNCYHAFDFCSTTRNEPFLHLFHCLYVYPVAVTLSRKRNPFIRVELRKDDTDIRKQPLEAIYPREPGVSLQKWVHTQVAVGARAASYHDEIKVSLPATWTPSHHLLFTFFHVDLQTKLEAPRPVVVGYASLPLSTYIHSRSDISLPVMRELVPHYLQESTKERLDYLEDGKNIFKLRLRLCSSLYPTNERVRDFCLEYDRHTLQTRPPWGSELLQAINSLKHVDSTALLQFLYPILNMLLHLIGNGGETLQVAAFRAMVDILTRVQQVSFDDADRNRFLVTYVDYSFDDFGGNQPPVYPGLATVWGSLARSKAKGYRVGPVYDDVLSMAWFFLELIVKSMALEQARLYDHNLPTGEDVPPMQLKESVFRCIMQLFDCLLTEVHERCKKGLSLAKRLNSSLAFFCYDLLYIIEPCQVYELVSLYMDKFSGVCQSVLHECKLTFLQIISDHDLFVEMPGRDPSDRNYLSSILIQELFLSLDHDELPLRAKGARILVILLCKHEFDARYQKAEDKLYIAQLYFPFVGQILDEMPVFYNLNATEKREVLIGVLQIVRNLDDTSLVKAWQQSIARTRLYFKLMEECLILFEHKKAADSILGGNNSRGPVSEGAGSPKYSERLSPAINNYLSEASRQEVRLEGTPDNGYLWQRVNSQLASPSQPYSLREALAQAQSSRIGASAQALRESLHPILRQKLELWEENVSATVSLQVLEITENFSSMAASHNIATDYGKLDCITTILTSFFSRNQSLAFWKAFFPIFNRIFDLHGATLMARENDRFLKQIAFHLLRLAVYRNDSVRKRAVIGLQILVKSSLYFMQTARLRALLTITLSELMSDVQVTHMKSDNTLEESGEARRLQQSLSEMADEAKSVNLLRECGLPDDTLLIIPEKFTENRWSWAEVKHLSDSLVLALDASLGHALLGSVMAMDRYAAAESFYKLGMAFAPVPDLHIMWLLHLCDAHQEMQSWAEAAQCAVAVAGVIMQALVARNDGVWSKDHVSALRKICPMVSGEFTTEASAAEVEGYGASKLTVDSAVKYLQLANKLFSQAELYHFCASILELVIPVYKSRKAYGQLAKCHTLLTNIYESILDQESNPIPFIDATYYRVGFYGEKFGKLDRKEYVYREPRDVRLGDIMEKLSHIYESRMDSNHILHIIPDSRQVKAEDLQAGVCYLQITAVDAVMEDEDLGSRRERIFSLSTGSVRARVFDRFLFDTPFTKNGKTQGGLEDQWKRRTVLQTEGSFPALVNRLLVTKSESLEFSPVENAIGMIETRTTALRNELEEPRSSDGDHLPRLQSLQRILQGSVAVQVNSGVLSVCTAFLSGEPATRLRSQELQQLIAALLEFMAVCKRAIRVHFRLIGEEDQEFHTQLVNGFQSLTAELSHYIPAILSEL", "length": 1830 }, "evidence": [ { "id": "A0A8M9PMX5", "url": "https://omabrowser.org/oma/group/A0A8M9PMX5/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VDR9-1", "protein_name": "Dedicator of cytokinesis protein 6", "gene_name": "Dock6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRSSSSLGVPLTEVIEPLDFEDVLLSRPPEVEPGPLRDLIEFPVDDLELLKQPRECRTTESGVPEDGQLDAQVRAAVEMYSEDWVIVRRRYQHLSTAYSPITTETQREWQKGLTCQVFEQDTPGDERTGPEDVDDPQHCSGSPEDTPRSSGASGIFSLRNLAADSLLPTLLEQAAPEDVDRRNEALRRQHRAPTLLTLYPAPDEDEAVERCSRPEPPREHFGQRILVKCLSLKFEIEIEPIFGTLALYDVREKKKISENFYFDLNSDSVKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVVKLEKVLQQGDISECCEPYMVMKEADTAKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSRPQDRDSDSEGERRPTWAERRRRGPQDRGYSGDDACSFSSFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKLDISPAPENLHFCLSPDLLHVKPYPDPRGRPTKEILEFPAREVYAPHSCYRNLLFVYPHSLNFSSRQGSVRNLAVRIQYMAGEDQSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLRLPACVTENHHLFFTFYHVSCQPRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQDPHLDKFFTLVHVLEEGIFPFRLKETVLSEGTMEQELRASLAALRLASPEPLVAFSHLVLDKLVRLVVRPPIICGQMVNLGRGAFEAMAHVASLVHRNLEAVQDSRGHCPLLASYVHYAFRLPGGDLSLPGEAPPATVQAATLARGSGRPASLYLARSKSISSSNPDLAVVPGSVDDEVSRILASKGVDRSHSWVNSAYAPGGSKAVLRRVPPYCGADPRQLLHEELALQWVVSGSAVRELVLQHAWFFFQLMVKSMELHLLLGQRLDTPRKLRFPGRFLDDIAALVASVGLEVITRVHKDMKLAERLNASLAFFLSDLLSIADRGYIFSLVRAHYKQVATRLQSAPNPTALLTLRMDFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQSSTFSSQAPDPKVTSMFELSGPFRQQHFLSGLLLTELALALDPEAEGASLLHKKAISAVHSLLCSHDVDSRYAEATVKAKVAELYLPLLSLARDTLPQLHGFAEGSGQRSRLASMLDSDTEGEGDIGSTINPSVAMAIAGGPLAPGSRTSISQGPSTAARSGCPLSAESSRTLLVCVLWVLKNAEPTLLQRWAADLALPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKARLEEAILGTIGARQEMVRRSRERSPFGNQENVRWRKSATHWRQTSDRVDKTKDEMEHEALVDGNLATEASLVVLDTLETIVQTVMLSEARESILSAVLKVVLYSLGSAQSALFLQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRMHASASLYLLMRQNFEIGHNFARVKMLVTMSLSSLVGTTQNFSEEHLRKSLKTILTYAEEDIGLRDSTFAEQVQDLMFNLHMILTDTVKMKEHQEDPEMLMDLMYRIARGYQGSPDLRLTWLQNMAGKHAELGNHAEAAQCMVHAAALVAEYLALLEDSRHLPVGCVSFQNVSSNVLEESAISDDILSPDEEGFCSGKNFTELGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYGTRFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKSKLDPQKAYIQITYVEPHFDTYELKDRVTYFDRNYGLRAFLFCTPFTPDGRAHGELAEQHKRKTLLSTEHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLSEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERHYSRLREALQPLLTQRLPQLLAPSSTSLRSSMNRSSFRKADL", "length": 2080 }, "evidence": [ { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96HP0-1", "protein_name": "Dedicator of cytokinesis protein 6", "gene_name": "DOCK6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASERRAFAHKINRTVAAEVRKQVSRERSGSPHSSRRCSSSLGVPLTEVVEPLDFEDVLLSRPPDAEPGPLRDLVEFPADDLELLLQPRECRTTEPGIPKDEKLDAQVRAAVEMYIEDWVIVHRRYQYLSAAYSPVTTDTQRERQKGLPRQVFEQDASGDERSGPEDSNDSRRGSGSPEDTPRSSGASSIFDLRNLAADSLLPSLLERAAPEDVDRRNETLRRQHRPPALLTLYPAPDEDEAVERCSRPEPPREHFGQRILVKCLSLKFEIEIEPIFGILALYDVREKKKISENFYFDLNSDSMKGLLRAHGTHPAISTLARSAIFSVTYPSPDIFLVIKLEKVLQQGDISECCEPYMVLKEVDTAKNKEKLEKLRLAAEQFCTRLGRYRMPFAWTAVHLANIVSSAGQLDRDSDSEGERRPAWTDRRRRGPQDRASSGDDACSFSGFRPATLTVTNFFKQEAERLSDEDLFKFLADMRRPSSLLRRLRPVTAQLKIDISPAPENPHFCLSPELLHIKPYPDPRGRPTKEILEFPAREVYAPHTSYRNLLYVYPHSLNFSSRQGSVRNLAVRVQYMTGEDPSQALPVIFGKSSCSEFTREAFTPVVYHNKSPEFYEEFKLHLPACVTENHHLLFTFYHVSCQPRPGTALETPVGFTWIPLLQHGRLRTGPFCLPVSVDQPPPSYSVLTPDVALPGMRWVDGHKGVFSVELTAVSSVHPQDPYLDKFFTLVHVLEEGAFPFRLKDTVLSEGNVEQELRASLAALRLASPEPLVAFSHHVLDKLVRLVIRPPIISGQIVNLGRGAFEAMAHVVSLVHRSLEAAQDARGHCPQLAAYVHYAFRLPGTEPSLPDGAPPVTVQAATLARGSGRPASLYLARSKSISSSNPDLAVAPGSVDDEVSRILASKLLHEELALQWVVSSSAVREAILQHAWFFFQLMVKSMALHLLLGQRLDTPRKLRFPGRFLDDITALVGSVGLEVITRVHKDVELAEHLNASLAFFLSDLLSLVDRGFVFSLVRAHYKQVATRLQSSPNPAALLTLRMEFTRILCSHEHYVTLNLPCCPLSPPASPSPSVSSTTSQSSTFSSQAPDPKVTSMFELSGPFRQQHFLAGLLLTELALALEPEAEGAFLLHKKAISAVHSLLCGHDTDPRYAEATVKARVAELYLPLLSIARDTLPRLHDFAEGPGQRSRLASMLDSDTEGEGDIAGTINPSVAMAIAGGPLAPGSRASISQGPPTASRAGCALSAESSRTLLACVLWVLKNTEPALLQRWATDLTLPQLGRLLDLLYLCLAAFEYKGKKAFERINSLTFKKSLDMKARLEEAILGTIGARQEMVRRSRERSPFGNPENVRWRKSVTHWKQTSDRVDKTKDEMEHEALVEGNLATEASLVVLDTLEIIVQTVMLSEARESVLGAVLKVVLYSLGSAQSALFLQHGLATQRALVSKFPELLFEEDTELCADLCLRLLRHCGSRISTIRTHASASLYLLMRQNFEIGHNFARVKMQVTMSLSSLVGTTQNFSEEHLRRSLKTILTYAEEDMGLRDSTFAEQVQDLMFNLHMILTDTVKMKEHQEDPEMLIDLMYRIARGYQGSPDLRLTWLQNMAGKHAELGNHAEAAQCMVHAAALVAEYLALLEDHRHLPVGCVSFQNISSNVLEESAISDDILSPDEEGFCSGKHFTELGLVGLLEQAAGYFTMGGLYEAVNEVYKNLIPILEAHRDYKKLAAVHGKLQEAFTKIMHQSSGWERVFGTYFRVGFYGAHFGDLDEQEFVYKEPSITKLAEISHRLEEFYTERFGDDVVEIIKDSNPVDKSKLDSQKAYIQITYVEPYFDTYELKDRVTYFDRNYGLRTFLFCTPFTPDGRAHGELPEQHKRKTLLSTDHAFPYIKTRIRVCHREETVLTPVEVAIEDMQKKTRELAFATEQDPPDAKMLQMVLQGSVGPTVNQGPLEVAQVFLAEIPEDPKLFRHHNKLRLCFKDFCKKCEDALRKNKALIGPDQKEYHRELERNYCRLREALQPLLTQRLPQLMAPTPPGLRNSLNRASFRKADL", "length": 2047 }, "evidence": [ { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96N67-1", "protein_name": "Dedicator of cytokinesis protein 7", "gene_name": "DOCK7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAERRAFAQKISRTVAAEVRKQISGQYSGSPQLLKNLNIVGNISHHTTVPLTEAVDPVDLEDYLITHPLAVDSGPLRDLIEFPPDDIEVVYSPRDCRTLVSAVPEESEMDPHVRDCIRSYTEDWAIVIRKYHKLGTGFNPNTLDKQKERQKGLPKQVFESDEAPDGNSYQDDQDDLKRRSMSIDDTPRGSWACSIFDLKNSLPDALLPNLLDRTPNEEIDRQNDDQRKSNRHKELFALHPSPDEEEPIERLSVPDIPKEHFGQRLLVKCLSLKFEIEIEPIFASLALYDVKEKKKISENFYFDLNSEQMKGLLRPHVPPAAITTLARSAIFSITYPSQDVFLVIKLEKVLQQGDIGECAEPYMIFKEADATKNKEKLEKLKSQADQFCQRLGKYRMPFAWTAIHLMNIVSSAGSLERDSTEVEISTGERKGSWSERRNSSIVGRRSLERTTSGDDACNLTSFRPATLTVTNFFKQEGDRLSDEDLYKFLADMRRPSSVLRRLRPITAQLKIDISPAPENPHYCLTPELLQVKLYPDSRVRPTREILEFPARDVYVPNTTYRNLLYIYPQSLNFANRQGSARNITVKVQFMYGEDPSNAMPVIFGKSSCSEFSKEAYTAVVYHNRSPDFHEEIKVKLPATLTDHHHLLFTFYHVSCQQKQNTPLETPVGYTWIPMLQNGRLKTGQFCLPVSLEKPPQAYSVLSPEVPLPGMKWVDNHKGVFNVEVVAVSSIHTQDPYLDKFFALVNALDEHLFPVRIGDMRIMENNLENELKSSISALNSSQLEPVVRFLHLLLDKLILLVIRPPVIAGQIVNLGQASFEAMASIINRLHKNLEGNHDQHGRNSLLASYIHYVFRLPNTYPNSSSPGPGGLGGSVHYATMARSAVRPASLNLNRSRSLSNSNPDISGTPTSPDDEVRSIIGSKGLDRSNSWVNTGGPKAAPWGSNPSPSAESTQAMDRSCNRMSSHTETSSFLQTLTGRLPTKKLFHEELALQWVVCSGSVRESALQQAWFFFELMVKSMVHHLYFNDKLEAPRKSRFPERFMDDIAALVSTIASDIVSRFQKDTEMVERLNTSLAFFLNDLLSVMDRGFVFSLIKSCYKQVSSKLYSLPNPSVLVSLRLDFLRIICSHEHYVTLNLPCSLLTPPASPSPSVSSATSQSSGFSTNVQDQKIANMFELSVPFRQQHYLAGLVLTELAVILDPDAEGLFGLHKKVINMVHNLLSSHDSDPRYSDPQIKARVAMLYLPLIGIIMETVPQLYDFTETHNQRGRPICIATDDYESESGSMISQTVAMAIAGTSVPQLTRPGSFLLTSTSGRQHTTFSAESSRSLLICLLWVLKNADETVLQKWFTDLSVLQLNRLLDLLYLCVSCFEYKGKKVFERMNSLTFKKSKDMRAKLEEAILGSIGARQEMVRRSRGQLGTYTIASPPERSPSGSAFGSQENLRWRKDMTHWRQNTEKLDKSRAEIEHEALIDGNLATEANLIILDTLEIVVQTVSVTESKESILGGVLKVLLHSMACNQSAVYLQHCFATQRALVSKFPELLFEEETEQCADLCLRLLRHCSSSIGTIRSHASASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSQNFNEEFLRRSLKTILTYAEEDLELRETTFPDQVQDLVFNLHMILSDTVKMKEHQEDPEMLIDLMYRIAKGYQTSPDLRLTWLQNMAGKHSERSNHAEAAQCLVHSAALVAEYLSMLEDRKYLPVGCVTFQNISSNVLEESAVSDDVVSPDEEGICSGKYFTESGLVGLLEQAAASFSMAGMYEAVNEVYKVLIPIHEANRDAKKLSTIHGKLQEAFSKIVHQSTGWERMFGTYFRVGFYGTKFGDLDEQEFVYKEPAITKLAEISHRLEGFYGERFGEDVVEVIKDSNPVDKCKLDPNKAYIQITYVEPYFDTYEMKDRITYFDKNYNLRRFMYCTPFTLDGRAHGELHEQFKRKTILTTSHAFPYIKTRVNVTHKEEIILTPIEVAIEDMQKKTQELAFATHQDPADPKMLQMVLQGSVGTTVNQGPLEVAQVFLSEIPSDPKLFRHHNKLRLCFKDFTKRCEDALRKNKSLIGPDQKEYQRELERNYHRLKEALQPLINRKIPQLYKAVLPVTCHRDSFSRMSLRKMDL", "length": 2140 }, "evidence": [ { "id": "RGD:1309790", "url": "https://alliancegenome.org/gene/RGD:1309790#orthology", "database": "AGR" }, { "id": "HGNC:19190", "url": "https://alliancegenome.org/gene/HGNC:19190#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050302-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050302-15#orthology", "database": "AGR" }, { "id": "MGI:1914549", "url": "https://alliancegenome.org/gene/MGI:1914549#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" }, { "id": "A0A8M9PMX5", "url": "https://omabrowser.org/oma/group/A0A8M9PMX5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VPI9-1", "protein_name": "Zizimin-related", "gene_name": "Zir", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSAQRSFVQKVSKQSAADVRKNVSGCHLSKAMDPSLCGSSISPTEPLDYEEFLSQHMNIINRDPLKHILDFPQGDVTVKIIPRKIRTVDHVVPNENLSDLPHHVQECVNCYTRPWKVVEYAQRHLSSSCYIRERIDRGTISPSAYQQEFEIDKDFSSFEEAFAYKSESCTPSSRQSIASLASVSSCTDTLTPRGSWASFDLRRSVNDPLIPNLLDNVPPEHIDQSNEARRQQDRQMALFSLYPESEAEENIERRLLAEIPVEHMGHRIQVNCLQLRLELEVEPIFASMAIYDAKERQKISENFYFDMNADSLKRMLSSHVQCADISTQSHSAIFEISYPSNDLFLVIRLEKVLQGDINNSVEPYLKEDKDKYREKVKSNAVDYCERLGKYRMPFAWTGIYLTNVFNGDNFESKDAGAAERDSFGNACGSSLGTAPSSNSLDRKSSTSSFDQLRRKANDMSGTLTRRGSLERKEKHRSWSPDDFANVVENFRPITITVPSFFKQEADKMKDEDLYKILPELKRPSSVMKKYKCIPGSIKLEISPCVEEAKNALTPELAPINPQSADNVRPVKEILEFPQSAIYNPHYSYRNLLFVSPKELNFSSRAGSARNIAVRVQLMAGETPKDAVNAIYGKSSCPKFSTEAFTAVNYHNKCPSFYDEIKIALPASIKQHHHLLFTIYHVSCQKKPQDLQPSVETPIGYTWLPLLEDGKLKFGEFNLPVMVESPPENYSFIPPNVHLPGIKWLDNHRAVFSINVEAVTAIHTLDSFLDRFFLICEYLDTRNIPSHIGENNIETELKKCLLDIEYANREPLVRHLPLVLDKLIELLVVTHKVGGQAMSLGSTVFEVLCLVSSLLSILNDDQYDQYGRQSLLSTYVHFQCKIPHPFQSKQRLTCSRSTTEDLQLSESYTIYDNVLASGRSLDRKELSIDVLHSMAARDVQVRLLHEELALHWVVASGKAADLAMSNSWFLFELIVKSMIEHLHCSNTLNGPRKHRFPHQFNDDLSTLVHLVTTKVVGYHSNEPKLAQSLNASLGFFIFDILSIMDRGFVFGLIKTYTKVLISKNASIPDLMNYKIDFLRIVCSHEHFVALNLPFGTSYTMVTAPCSPTPSTTSSNSQTSCGSLERALHADLSQEFLQQHFLVGLVLSDLAAVMEVPNPQLHGKAIRCIRNLMTSHDLDARYSETDARARVAALYIPLLSIVMDCIPQLHQHGLEQDRLQQIGQLEDYQGPHQTITASTINPEVAFAISGSRPYSYLNEQVKNKLPLSSENTRHLLVCFLWVLKNLERNVLYRWLMDLSPHRVHQMLQGVNVCLKTFEYTGQKNVATLKRTNTQSFRKTGSTDVKEKLEECIRGTNSARYDLINRRKDRNSTEKFRWRKDQMPYRSQYADAVGKSEHELELSHFIEGSLATEVALVLLDTLEIIVHAAANLYHNLLGTVLKVLLHSLSRNQSVLALQNLFASQRALIFKFPNLLFDDETDICADLCLILLKHCGSLLPGIRSQAAASLYLLMRQNFEIGNNFARVKMQVTMSLSSLVGTSSVFSEQSLRRALKTVLVYAESDSDLQDTSFPEQVQDLLFNLHMILSDTVKMKEYQEDPEMLLDLMNRIAKGYQNNPDLRLTWLENMAKKHRERANHTEAAMCYVHAASLVSEYLSMLESQKHLPVGAVSFQRISPNTLMESAVSDDVLSPGEDGICLGNHFTETGLKALLEEASNSFQVAGMYEAMNEVYKILIPICEANRDFQKLSKVHGKLQEAFNRISQLQGKRVFGTYFRVGFYGGKFGDLDQQEFIYKEPTLTKLPEIFSRLQNFYTERFGPDSVHIIKDSNTVDINSLDPDKAYIQITYVEPYFETYEMRHRETYFERNFNIKRFIYATPFTKNGKAHGELNEQCKRKTILTTANHFPYVKTRIMVISRQQIVLEPIEVAIEDIQKKTLELAAATNQEPADPKILQMVLQGCIGTTVNQGPMEMASVFLSNLSDGTTVPTKHQNKLRLCFREFSKRCADALKKNRNLILSDQKDYQRELERNNDRFIERLTPFITLTSVQNHGVVKANAYNNKSTPLKW", "length": 2064 }, "evidence": [ { "id": "RGD:1309790", "url": "https://alliancegenome.org/gene/RGD:1309790#orthology", "database": "AGR" }, { "id": "HGNC:19190", "url": "https://alliancegenome.org/gene/HGNC:19190#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050302-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050302-15#orthology", "database": "AGR" }, { "id": "MGI:1914549", "url": "https://alliancegenome.org/gene/MGI:1914549#orthology", "database": "AGR" }, { "id": "FB:FBgn0031216", "url": "https://alliancegenome.org/gene/FB:FBgn0031216#orthology", "database": "AGR" }, { "id": "A0A8M9PMX5", "url": "https://omabrowser.org/oma/group/A0A8M9PMX5/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMX5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMX5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5" } ], "pmid": "" }, { "name": "axonogenesis", "id": "GO:0007409", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007409", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMX5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5" } ], "pmid": "" }, { "name": "regulation of Rho protein signal transduction", "id": "GO:0035023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035023", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMX5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1069, "end_pos": 1071, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1509, "end_pos": 1511, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1551, "end_pos": 1553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1731, "end_pos": 1733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2070, "end_pos": 2072, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" }, { "start_pos": 580, "end_pos": 582, "annotation": "n_glycosylation_sequon" }, { "start_pos": 621, "end_pos": 623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 776, "end_pos": 778, "annotation": "n_glycosylation_sequon" }, { "start_pos": 890, "end_pos": 892, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PMX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5" }, { "id": "PS51650", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51650" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 DOCK-type", "eco_id": "ECO_0000259", "start_pos": 559, "end_pos": 725, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PMX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMX5" }, { "id": "PS51651", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51651" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOCKER", "eco_id": "ECO_0000259", "start_pos": 1669, "end_pos": 2105, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1069, "end_pos": 1071 }, { "start_pos": 1509, "end_pos": 1511 }, { "start_pos": 1551, "end_pos": 1553 }, { "start_pos": 1731, "end_pos": 1733 }, { "start_pos": 2070, "end_pos": 2072 }, { "start_pos": 36, "end_pos": 38 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 555, "end_pos": 557 }, { "start_pos": 580, "end_pos": 582 }, { "start_pos": 621, "end_pos": 623 }, { "start_pos": 776, "end_pos": 778 }, { "start_pos": 890, "end_pos": 892 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PMJ1-1", "uniprot_ac": "A0A8M9PMJ1", "uniprot_id": "A0A8M9PMJ1_DANRE", "mass": { "chemical_mass": 45673.0, "monoisotopic_mass": 45673.0 }, "refseq": { "ac": "XP_021332702", "name": "PTB domain-containing engulfment adapter protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332702" }, "gene_names": [ { "name": "gulp1b", "type": "recommended", "evidence": [ { "id": "A0A8M9PMJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1" } ] }, { "name": "gulp1b", "type": "synonym", "evidence": [ { "id": "XP_021332702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332702" } ] } ], "protein_names": [ { "name": "PTB domain-containing engulfment adapter protein 1", "type": "recommended", "evidence": [ { "id": "A0A8M9PMJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1/entry#names_and_taxonomy" } ] }, { "name": "Cell death protein 6 homolog", "type": "synonym", "evidence": [ { "id": "A0A8M9PMJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1/entry#names_and_taxonomy" } ] }, { "name": "PTB domain adapter protein CED-6", "type": "synonym", "evidence": [ { "id": "A0A8M9PMJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1/entry#names_and_taxonomy" } ] }, { "name": "PTB domain-containing engulfment adapter protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021332702", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332702" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021332702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332702" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gulp1b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120228-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120228-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PMJ1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PMJ1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000057833", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000057833", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100006392", "url": "https://www.ncbi.nlm.nih.gov/gene/100006392", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100006392", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006392", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DYIVPRP", "url": "https://omabrowser.org/oma/group/DYIVPRP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M1Q7Y4", "url": "https://www.orthodb.org/?gene=A0A8M1Q7Y4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BD73", "url": "https://www.orthodb.org/?gene=A0A8M2BD73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3B097", "url": "https://www.orthodb.org/?gene=A0A8M3B097", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PMJ1", "url": "https://www.orthodb.org/?gene=A0A8M9PMJ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FG11", "url": "https://www.orthodb.org/?gene=E7FG11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11232:SF70", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11232:SF70", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021332702", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332702", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M1Q7Y4", "url": "https://www.uniprot.org/uniprotkb/A0A8M1Q7Y4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1Q7Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1Q7Y4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BD73", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BD73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BD73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BD73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B097", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B097", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B097-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B097-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PMJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q075", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q075", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q075-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q075-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FG11", "url": "https://www.uniprot.org/uniprotkb/E7FG11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FG11-1", "url": "https://www.uniprot.org/uniprotkb/E7FG11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120228-2", "url": "https://zfin.org/ZDB-GENE-120228-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRLDGLRVEGNNYKINLPCGLTLESALSLQALLKLCRMNRAFNRRKDKPSMHTPEALVKSHVVYNAKFLGITEVDQPKGTDMVRVAVRKLKFQRHIKKSEGHKTPKVELQISIYGVKILDPKTKEMLHNCQLHRMSFCADDKTDKRIFTFICTEPETKKHLCYVFDSEKCAEEITLAIGQAFDLAYKKFLESGGKDVETRKQIGNLQKRIQDLEMENSKLKKKLKELEDQLTDPRCSPRASTLSWCGEDVTSLSSLEISSVTLTPVSSPDSSQSASLLTPPPAKPTHSQPKSDYIVPRPRTGSIQARAPSTDIFDMVPFTPESPITRRLNFNGFSSPYLTPKDTDIDLFGAEPFDPFICGPTVFTPDMQSKLDEMQRQRWFEGFQMGLTLEGTVFSLEPVDSRC", "length": 404, "header": "tr|A0A8M9PMJ1-1|A0A8M9PMJ1_DANRE Isoform 1 of PTB domain-containing engulfment adapter protein 1 OS=Danio rerio OX=7955 GN=gulp1b PE=3 SV=1 CANONICAL=A0A8M9PMJ1-1" }, "isoforms": [ { "isoform_ac": "A0A8M1Q7Y4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1/entry#A0A8M1Q7Y4-1", "sequence": { "sequence": "MRLDGLRVEGNNYKINLPCGLTLESALSLQALLKLCRMNRAFNRRKDKPSMHTPEALVKSHVVYNAKFLGITEVDQPKGTDMVRVAVRKLKFQRHIKKSEGHKTPKVELQISIYGVKILDPKTKEMLHNCQLHRMSFCADDKTDKRIFTFICTEPETKKHLCYVFDSEKCAEEITLAIGQAFDLAYKKFLESGGKDVETRKQIGNLQKRIQDLEMENSKLKKKLKELEDQLTDPRCSPTGSIQARAPSTDIFDMVPFTPESPITRRLNFNGFSSPYLTPKDTDIDLFGAEPFDPFICGPTVFTPDMQSKLDEMQEGFQMGLTLEGTVFSLEPVDSRC", "length": 337, "header": "tr|A0A8M1Q7Y4-1|A0A8M9PMJ1_DANRE Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Danio rerio OX=7955 GN=gulp1b PE=3 SV=1 CANONICAL=A0A8M9PMJ1-1" }, "locus": {} }, { "isoform_ac": "A0A8M2BD73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1/entry#A0A8M2BD73-1", "sequence": { "sequence": "MRLDGLRVEGNNYKINLPCGLTLESALSLQALLKLCRMNRAFNRRKDKPSMHTPEALVKSHVVYNAKFLGITEVDQPKGTDMVRVAVRKLKFQRHIKKSEGHKTPKVELQISIYGVKILDPKTKEMLHNCQLHRMSFCADDKTDKRIFTFICTEPETKKHLCYVFDSEKCAEEITLAIGQAFDLAYKKFLESGGKDVETRKQIGNLQKRIQDLEMENSKLKKKLKELEDQLTDPRCSPTGSIQARAPSTDIFDMVPFTPESPITRRLNFNGFSSPYLTPKDTDIDLFGAEPFDPFICGPTVFTPDMQSKLDEMQRQRWRGSKWD", "length": 324, "header": "tr|A0A8M2BD73-1|A0A8M9PMJ1_DANRE Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Danio rerio OX=7955 GN=gulp1b PE=3 SV=1 CANONICAL=A0A8M9PMJ1-1" }, "locus": {} }, { "isoform_ac": "A0A8M3B097-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1/entry#A0A8M3B097-1", "sequence": { "sequence": "MRLDGLRVEGNNYKINLPCGLTLESALSLQALLKLCRMNRAFNRRKDKPSMHTPEALVKSHVVYNAKFLGITEVDQPKGTDMVRVAVRKLKFQRHIKKSEGHKTPKVELQISIYGVKILDPKTKEMLHNCQLHRMSFCADDKTDKRIFTFICTEPETKKHLCYVFDSEKCAEEITLAIGQAFDLAYKKFLESGGKDVETRKQIGNLQKRIQDLEMENSKLKKKLKELEDQLTDPRCSPRASTLSWCGEDVTSLSSLEISSVTLTPVSSPDSSQSASLLTPPPAKPTHSQPKSDYIVPRPRTGSIQARAPSTDIFDMVPFTPESPITRRLNFNGFSSPYLTPKDTDIDLFGAEPFDPFICGPTVFTPDMQSKLDEMQRQRWRGSKWD", "length": 386, "header": "tr|A0A8M3B097-1|A0A8M9PMJ1_DANRE Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Danio rerio OX=7955 GN=gulp1b PE=3 SV=1 CANONICAL=A0A8M9PMJ1-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PMJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1/entry#A0A8M9PMJ1-1", "sequence": { "sequence": "MRLDGLRVEGNNYKINLPCGLTLESALSLQALLKLCRMNRAFNRRKDKPSMHTPEALVKSHVVYNAKFLGITEVDQPKGTDMVRVAVRKLKFQRHIKKSEGHKTPKVELQISIYGVKILDPKTKEMLHNCQLHRMSFCADDKTDKRIFTFICTEPETKKHLCYVFDSEKCAEEITLAIGQAFDLAYKKFLESGGKDVETRKQIGNLQKRIQDLEMENSKLKKKLKELEDQLTDPRCSPRASTLSWCGEDVTSLSSLEISSVTLTPVSSPDSSQSASLLTPPPAKPTHSQPKSDYIVPRPRTGSIQARAPSTDIFDMVPFTPESPITRRLNFNGFSSPYLTPKDTDIDLFGAEPFDPFICGPTVFTPDMQSKLDEMQRQRWFEGFQMGLTLEGTVFSLEPVDSRC", "length": 404, "header": "tr|A0A8M9PMJ1-1|A0A8M9PMJ1_DANRE Isoform 1 of PTB domain-containing engulfment adapter protein 1 OS=Danio rerio OX=7955 GN=gulp1b PE=3 SV=1 CANONICAL=A0A8M9PMJ1-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q075-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1/entry#A0A8M9Q075-1", "sequence": { "sequence": "MRLDGLRVEGNNYKINLPCGLTLESALSLQALLKLCRMNRAFNRRKDKPSMHTPEALVKSHVVYNAKFLGITEVDQPKGTDMVRVAVRKLKFQRHIKKSEGHKTPKVELQISIYGVKILDPKTKEMLHNCQLHRMSFCADDKTDKRIFTFICTEPETKKHLCYVFDSEKCAEEITLAIGQAFDLAYKKFLESGGKDVETRKQIGNLQKRIQDLEMENSKLKKKLKELEDQLTDPRCSPTGSIQARAPSTDIFDMVPFTPESPITRRLNFNGFSSPYLTPKDTDIDLFGAEPFDPFICGPTVFTPDMQSKLDEMQRQRWFEGFQMGLTLEGTVFSLEPVDSRC", "length": 342, "header": "tr|A0A8M9Q075-1|A0A8M9PMJ1_DANRE Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Danio rerio OX=7955 GN=gulp1b PE=3 SV=1 CANONICAL=A0A8M9PMJ1-1" }, "locus": {} }, { "isoform_ac": "E7FG11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1/entry#E7FG11-1", "sequence": { "sequence": "MRLDGLRVEGNNYKINLPCGLTLESALSLQALLKLCRMNRAFNRRKDKPSMHTPEALVKSHVVYNAKFLGITEVDQPKGTDMVRVAVRKLKFQRHIKKSEGHKTPKVELQISIYGVKILDPKTKEMLHNCQLHRMSFCADDKTDKRIFTFICTEPETKKHLCYVFDSEKCAEEITLAIGQAFDLAYKKFLESGGKDVETRKQIGNLQKRIQDLEMENSKLKKKLKELEDQLTDPRCSPRASTLSWCGEDVTSLSSLEISSVTLTPVSSPDSSQSASLLTPPPAKPTHSQPKSDYIVPRPRTGSIQARAPSTDIFDMVPFTPESPITRRLNFNGFSSPYLTPKDTDIDLFGAEPFDPFICGPTVFTPDMQSKLDEMQEGFQMGLTLEGTVFSLEPVDSRC", "length": 399, "header": "tr|E7FG11-1|E7FG11_DANRE Computationally mapped isoform of PTB domain-containing engulfment adapter protein 1 OS=Danio rerio OX=7955 GN=gulp1b PE=3 SV=1 CANONICAL=A0A8M9PMJ1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100006392", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006392", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q32PV0-1", "protein_name": "PTB domain-containing engulfment adapter protein 1", "gene_name": "gulp1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNRAFNRKKDKSWMHTPEALAKHFIPYNAKFLGNTEVDQPKGTEVVKDAVRKLKFQRHIKKSEGQKLPKVELQISIYGVKILDPKSKEVQYNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYKKFLESGGKDVETRKQIGGLQKRIQDLETENVELKKQLQVLEEQLMIAQVPPGNSMSSKSPTDIFDMVPFSPMTPLVPLPASNGSAPPPPARPTEIRRDLFGAEPFDPFTCGAADFPPDIQSKLDEMQEGFKMGLTVEGTVFSLDPLEGRC", "length": 300 }, "evidence": [ { "id": "RGD:1306380", "url": "https://alliancegenome.org/gene/RGD:1306380#orthology", "database": "AGR" }, { "id": "HGNC:18649", "url": "https://alliancegenome.org/gene/HGNC:18649#orthology", "database": "AGR" }, { "id": "MGI:1920407", "url": "https://alliancegenome.org/gene/MGI:1920407#orthology", "database": "AGR" }, { "id": "FB:FBgn0029092", "url": "https://alliancegenome.org/gene/FB:FBgn0029092#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5PQS4-1", "protein_name": "PTB domain-containing engulfment adapter protein 1", "gene_name": "Gulp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNRAFSRKKDKTWMHMPEALSKHYVPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCFVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGMQKRIQDLETENMELKNKVQDLENRLRTTQVSSTPAGGVTVTSPSTDIFDMIPFSPISHPSPTSAGNGTQLPPIPSRSSEIKRDLFGAEPFDPFNCGAGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 304 }, "evidence": [ { "id": "RGD:1306380", "url": "https://alliancegenome.org/gene/RGD:1306380#orthology", "database": "AGR" }, { "id": "HGNC:18649", "url": "https://alliancegenome.org/gene/HGNC:18649#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120228-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120228-2#orthology", "database": "AGR" }, { "id": "MGI:1920407", "url": "https://alliancegenome.org/gene/MGI:1920407#orthology", "database": "AGR" }, { "id": "FB:FBgn0029092", "url": "https://alliancegenome.org/gene/FB:FBgn0029092#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7JUY7-1", "protein_name": "PTB domain-containing adapter protein ced-6", "gene_name": "ced-6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPYQPANSGGTSGGSKAAAKMAQLKFWNKQNSSKQQQQDKDKDAADGGNNTSGGGTGSNSNGDAKSEAKNGKRNWLHTPEQLISGHAVYLVKFFGNLSVDQPKGIEVVKEAIRKLQFAQQMKKAETGTQEKFKKLEITISIKGVAIQEPRTHKILHQFPLYNISYCADEKGVKKFFSFIAKTVKTQDGSDPTSNGHANGNGDGSAKVEESHECFVFISNKLASDITLTIGQAFDLAYRKYMDSTEKTNLSKAQQQINHLQQTVNVYKERLREVSAKLPKAELDALLFNLGIKDILEAPTTEPQNGIEVASEALSNGKLDDDKLLIDTNSTTASTHSASPSSFLPIVPPRNNLSSQISIGGKSNSQKMDELLLNSDSDSDFDPRADETQEIGGTGRSAISNMFGFEPANSFGQHLFSNNNDHKLQNNNSSLLITSNNNSINSSGFSSELNITPPLLAPPPKIAAPRRLNSVTTGNGLNGNTDLFGSDPFELNNGPNIFKQNQLNLDDFSLESLDPLRK", "length": 517 }, "evidence": [ { "id": "RGD:1306380", "url": "https://alliancegenome.org/gene/RGD:1306380#orthology", "database": "AGR" }, { "id": "HGNC:18649", "url": "https://alliancegenome.org/gene/HGNC:18649#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120228-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120228-2#orthology", "database": "AGR" }, { "id": "MGI:1920407", "url": "https://alliancegenome.org/gene/MGI:1920407#orthology", "database": "AGR" }, { "id": "FB:FBgn0029092", "url": "https://alliancegenome.org/gene/FB:FBgn0029092#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8K2A1-1", "protein_name": "PTB domain-containing engulfment adapter protein 1", "gene_name": "Gulp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHYIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCFVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGMQKRIQDLETENMELKNKVQDLESRLRTTQVSTSPAHGVTVMSPSTDIFDMIPFSPISHQSPTSARNGTQLPPIPSRSAETKRDLFGAEPFDPFNCGSGDFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 304 }, "evidence": [ { "id": "RGD:1306380", "url": "https://alliancegenome.org/gene/RGD:1306380#orthology", "database": "AGR" }, { "id": "HGNC:18649", "url": "https://alliancegenome.org/gene/HGNC:18649#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120228-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120228-2#orthology", "database": "AGR" }, { "id": "MGI:1920407", "url": "https://alliancegenome.org/gene/MGI:1920407#orthology", "database": "AGR" }, { "id": "FB:FBgn0029092", "url": "https://alliancegenome.org/gene/FB:FBgn0029092#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UBP9-1", "protein_name": "PTB domain-containing engulfment adapter protein 1", "gene_name": "GULP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRAFSRKKDKTWMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVELQISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEKCAEEITLTIGQAFDLAYRKFLESGGKDVETRKQIAGLQKRIQDLETENMELKNKVQDLENQLRITQVSAPPAGSMTPKSPSTDIFDMIPFSPISHQSSMPTRNGTQPPPVPSRSTEIKRDLFGAEPFDPFNCGAADFPPDIQSKLDEMQEGFKMGLTLEGTVFCLDPLDSRC", "length": 304 }, "evidence": [ { "id": "RGD:1306380", "url": "https://alliancegenome.org/gene/RGD:1306380#orthology", "database": "AGR" }, { "id": "HGNC:18649", "url": "https://alliancegenome.org/gene/HGNC:18649#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120228-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120228-2#orthology", "database": "AGR" }, { "id": "MGI:1920407", "url": "https://alliancegenome.org/gene/MGI:1920407#orthology", "database": "AGR" }, { "id": "FB:FBgn0029092", "url": "https://alliancegenome.org/gene/FB:FBgn0029092#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phagocytosis", "id": "GO:0006909", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006909", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMJ1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PMJ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMJ1" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 192, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0S5T6-1", "uniprot_ac": "B0S5T6", "uniprot_id": "B0S5T6_DANRE", "mass": { "chemical_mass": 67329.0, "monoisotopic_mass": 67329.0 }, "refseq": { "ac": "XP_068079762", "name": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079762" }, "gene_names": [ { "name": "ppp2r3b", "type": "recommended", "evidence": [ { "id": "B0S5T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S5T6" } ] }, { "name": "ppp2r3b", "type": "synonym", "evidence": [ { "id": "XP_068079762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079762" } ] } ], "protein_names": [ { "name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1", "type": "synonym", "evidence": [ { "id": "B0S5T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S5T6/entry#names_and_taxonomy" } ] }, { "name": "serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1", "type": "synonym", "evidence": [ { "id": "XP_068079762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079762" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068079762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079762" } ] }, { "annotation": "The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M2BFY8", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BFY8#function" }, { "database": "UniProtKB", "id": "ARBA00093310", "url": "https://www.uniprot.org/uniprotkb/ARBA00093310#function" }, { "database": "UniProtKB", "id": "A0A8M9Q569", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q569#function" }, { "database": "UniProtKB", "id": "A0A8M9QBH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBH6#function" }, { "database": "UniProtKB", "id": "A0A8M9QKA7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKA7#function" }, { "database": "UniProtKB", "id": "B0S5T6", "url": "https://www.uniprot.org/uniprotkb/B0S5T6#function" }, { "database": "UniProtKB", "id": "A0AC58GGY8", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGY8#function" } ] } ], "disease": [ { "disease_id": "DOID:0060250", "recommended_name": { "id": "DOID:0060250", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060250", "name": "idiopathic scoliosis", "description": "A scoliosis with no known cause." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0060250", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060250" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S5T6", "url": "https://www.uniprot.org/uniprotkb/B0S5T6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ppp2r3b", "url": "https://www.uniprot.org/uniprotkb/B0S5T6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-268", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-268", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000076004", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000076004", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "566032", "url": "https://www.ncbi.nlm.nih.gov/gene/566032", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566032", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566032", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPENECY", "url": "https://omabrowser.org/oma/group/GPENECY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BFY8", "url": "https://www.orthodb.org/?gene=A0A8M2BFY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "B0S5T6", "url": "https://www.orthodb.org/?gene=B0S5T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14095", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14095", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14095:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14095:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17958", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17958", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21161", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21161", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-113501", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-113501", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-69231", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-69231", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-69273", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-69273", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_068079762", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079762", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BFY8", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BFY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BFY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BFY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q569", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q569", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q569-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q569-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QBH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QBH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QBH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QKA7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QKA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QKA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGY8", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S5T6", "url": "https://www.uniprot.org/uniprotkb/B0S5T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S5T6-1", "url": "https://www.uniprot.org/uniprotkb/B0S5T6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-268", "url": "https://zfin.org/ZDB-GENE-070912-268", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASPQTLQPVLKMKVDELFLFWLSEPSTQAMLKDYLNKIKSGEEIDLSHGEFKGTSTLMFTENNNNNIASKINATERMSAALGAPCSPPSATLPSATGSNNRAGVNARALRRSVSTKKQAQAKKEEPVTPALSESIPKFYFPRGQPQANINIDNLISKIEKIFSQFPDERVTIKDMGLVAKACDCPFYWKAPLFHAAGGDRRGYVSVHKFVAMWRKVLQTCHDDASKFLHLLAKPGCNYLEQEDFIPFLQDVVDSHTGLAFLKEASDFHSRYITTVVQRIFYNVNRSWTGKITCSELRRSTFLQNVALLEEDEEINQLTEFFSYEHFYVIYCKFWELDTDHDLYIDQRDLMRHNDQAISHRMIERIFSGAVTRGRAVHKEGRLSYGDFVWFLISEEDKKTETSIEYWFRCMDLDGDGVLSMYELQYFYQEQCQKLEAMAIEPLPFEDCLCQMLDLVKPENPGKITLRDLKRCRMSHIFFDTFFNIEKYLDHEQRDPLLAARDAEAVGQEISDWERYAAEEYDNLVAEETANEQYHDGYDNILDPADHVTSALELHSEKRHLFGIPSPHCNLDLDEYEYEDDFE", "length": 583, "header": "tr|B0S5T6-1|B0S5T6_DANRE Isoform 1 of Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 OS=Danio rerio OX=7955 GN=ppp2r3b PE=1 SV=1 CANONICAL=B0S5T6-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BFY8-1", "url": "https://www.uniprot.org/uniprotkb/B0S5T6/entry#A0A8M2BFY8-1", "sequence": { "sequence": "MASPQTLQPVLKMKVDELFLFWLSEPSTQAMLKDYLNKIKSGEEIDLSHGEFKGTSTLMFTENNNNNIASKINATERMSAALGAPCSPPSATLPSATGSNNRAGVNARALRRSVSTKKAQAKKEEPVTPALSESIPKFYFPRGQPQANINIDNLISKIEKIFSQFPDERVTIKDMGLVAKACDCPFYWKAPLFHAAGGDRRGYVSVHKFVAMWRKVLQTCHDDASKFLHLLAKPGCNYLEQEDFIPFLQDVVDSHTGLAFLKEASDFHSRYITTVVQRIFYNVNRSWTGKITCSELRRSTFLQNVALLEEDEEINQLTEFFSYEHFYVIYCKFWELDTDHDLYIDQRDLMRHNDQAISHRMIERIFSGAVTRGRAVHKEGRLSYGDFVWFLISEEDKKTETSIEYWFRCMDLDGDGVLSMYELQYFYQEQCQKLEAMAIEPLPFEDCLCQMLDLVKPENPGKITLRDLKRCRMSHIFFDTFFNIEKYLDHEQRDPLLAARDAEAVGQEISDWERYAAEEYDNLVAEETANEQYHDGYDNILDPADHVTSALELHSEKRHLFGIPSPHCNLDLDEYEYEDDFE", "length": 582, "header": "tr|A0A8M2BFY8-1|B0S5T6_DANRE Computationally mapped isoform of Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 OS=Danio rerio OX=7955 GN=ppp2r3b PE=1 SV=1 CANONICAL=B0S5T6-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q569-1", "url": "https://www.uniprot.org/uniprotkb/B0S5T6/entry#A0A8M9Q569-1", "sequence": { "sequence": "MRMKEISLRQDPDLRKELALLARGCDFVLPSRFKKRLKAFQQGQAGCLQAQAKKEEPVTPALSESIPKFYFPRGQPQANINIDNLISKIEKIFSQFPDERVTIKDMGLVAKACDCPFYWKAPLFHAAGGDRRGYVSVHKFVAMWRKVLQTCHDDASKFLHLLAKPGCNYLEQEDFIPFLQDVVDSHTGLAFLKEASDFHSRYITTVVQRIFYNVNRSWTGKITCSELRRSTFLQNVALLEEDEEINQLTEFFSYEHFYVIYCKFWELDTDHDLYIDQRDLMRHNDQAISHRMIERIFSGAVTRGRAVHKEGRLSYGDFVWFLISEEDKKTETSIEYWFRCMDLDGDGVLSMYELQYFYQEQCQKLEAMAIEPLPFEDCLCQMLDLVKPENPGKITLRDLKRCRMSHIFFDTFFNIEKYLDHEQRDPLLAARDAEAVGQEISDWERYAAEEYDNLVAEETANEQYHDGYDNILDPADHVTSALELHSEKRHLFGIPSPHCNLDLDEYEYEDDFE", "length": 513, "header": "tr|A0A8M9Q569-1|B0S5T6_DANRE Computationally mapped isoform of Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 OS=Danio rerio OX=7955 GN=ppp2r3b PE=1 SV=1 CANONICAL=B0S5T6-1" }, "locus": {} }, { "isoform_ac": "A0A8M9QBH6-1", "url": "https://www.uniprot.org/uniprotkb/B0S5T6/entry#A0A8M9QBH6-1", "sequence": { "sequence": "MRMKEISLRQDPDLRKELALLARGCDFVLPSRFKKRLKAFQQGQQAQAKKEEPVTPALSESIPKFYFPRGQPQANINIDNLISKIEKIFSQFPDERVTIKDMGLVAKACDCPFYWKAPLFHAAGGDRRGYVSVHKFVAMWRKVLQTCHDDASKFLHLLAKPGCNYLEQEDFIPFLQDVVDSHTGLAFLKEASDFHSRYITTVVQRIFYNVNRSWTGKITCSELRRSTFLQNVALLEEDEEINQLTEFFSYEHFYVIYCKFWELDTDHDLYIDQRDLMRHNDQAISHRMIERIFSGAVTRGRAVHKEGRLSYGDFVWFLISEEDKKTETSIEYWFRCMDLDGDGVLSMYELQYFYQEQCQKLEAMAIEPLPFEDCLCQMLDLVKPENPGKITLRDLKRCRMSHIFFDTFFNIEKYLDHEQRDPLLAARDAEAVGQEISDWERYAAEEYDNLVAEETANEQYHDGYDNILDPADHVTSALELHSEKRHLFGIPSPHCNLDLDEYEYEDDFE", "length": 509, "header": "tr|A0A8M9QBH6-1|B0S5T6_DANRE Computationally mapped isoform of Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 OS=Danio rerio OX=7955 GN=ppp2r3b PE=1 SV=1 CANONICAL=B0S5T6-1" }, "locus": {} }, { "isoform_ac": "A0A8M9QKA7-1", "url": "https://www.uniprot.org/uniprotkb/B0S5T6/entry#A0A8M9QKA7-1", "sequence": { "sequence": "MRMKEISLRQDPDLRKELALLARGCDFVLPSRFKKRLKAFQQGQAQAKKEEPVTPALSESIPKFYFPRGQPQANINIDNLISKIEKIFSQFPDERVTIKDMGLVAKACDCPFYWKAPLFHAAGGDRRGYVSVHKFVAMWRKVLQTCHDDASKFLHLLAKPGCNYLEQEDFIPFLQDVVDSHTGLAFLKEASDFHSRYITTVVQRIFYNVNRSWTGKITCSELRRSTFLQNVALLEEDEEINQLTEFFSYEHFYVIYCKFWELDTDHDLYIDQRDLMRHNDQAISHRMIERIFSGAVTRGRAVHKEGRLSYGDFVWFLISEEDKKTETSIEYWFRCMDLDGDGVLSMYELQYFYQEQCQKLEAMAIEPLPFEDCLCQMLDLVKPENPGKITLRDLKRCRMSHIFFDTFFNIEKYLDHEQRDPLLAARDAEAVGQEISDWERYAAEEYDNLVAEETANEQYHDGYDNILDPADHVTSALELHSEKRHLFGIPSPHCNLDLDEYEYEDDFE", "length": 508, "header": "tr|A0A8M9QKA7-1|B0S5T6_DANRE Computationally mapped isoform of Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 OS=Danio rerio OX=7955 GN=ppp2r3b PE=1 SV=1 CANONICAL=B0S5T6-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGY8-1", "url": "https://www.uniprot.org/uniprotkb/B0S5T6/entry#A0AC58GGY8-1", "sequence": { "sequence": "MGLVAKACDCPFYWKAPLFHAAGGDRRGYVSVHKFVAMWRKVLQTCHDDASKFLHLLAKPGCNYLEQEDFIPFLQDVVDSHTGLAFLKEASDFHSRYITTVVQRIFYNVNRSWTGKITCSELRRSTFLQNVALLEEDEEINQLTEFFSYEHFYVIYCKFWELDTDHDLYIDQRDLMRHNDQAISHRMIERIFSGAVTRGRAVHKEGRLSYGDFVWFLISEEDKKTETSIEYWFRCMDLDGDGVLSMYELQYFYQEQCQKLEAMAIEPLPFEDCLCQMLDLVKPENPGKITLRDLKRCRMSHIFFDTFFNIEKYLDHEQRDPLLAARDAEAVGQEISDWERYAAEEYDNLVAEETANEQYHDGYDNILDPADHVTSALELHSEKRHLFGIPSPHCNLDLDEYEYEDDFE", "length": 408, "header": "tr|A0AC58GGY8-1|A0AC58GGY8_DANRE Computationally mapped isoform of Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X6 OS=Danio rerio OX=7955 GN=ppp2r3b PE=4 SV=1 CANONICAL=B0S5T6-1" }, "locus": {} }, { "isoform_ac": "B0S5T6-1", "url": "https://www.uniprot.org/uniprotkb/B0S5T6/entry#B0S5T6-1", "sequence": { "sequence": "MASPQTLQPVLKMKVDELFLFWLSEPSTQAMLKDYLNKIKSGEEIDLSHGEFKGTSTLMFTENNNNNIASKINATERMSAALGAPCSPPSATLPSATGSNNRAGVNARALRRSVSTKKQAQAKKEEPVTPALSESIPKFYFPRGQPQANINIDNLISKIEKIFSQFPDERVTIKDMGLVAKACDCPFYWKAPLFHAAGGDRRGYVSVHKFVAMWRKVLQTCHDDASKFLHLLAKPGCNYLEQEDFIPFLQDVVDSHTGLAFLKEASDFHSRYITTVVQRIFYNVNRSWTGKITCSELRRSTFLQNVALLEEDEEINQLTEFFSYEHFYVIYCKFWELDTDHDLYIDQRDLMRHNDQAISHRMIERIFSGAVTRGRAVHKEGRLSYGDFVWFLISEEDKKTETSIEYWFRCMDLDGDGVLSMYELQYFYQEQCQKLEAMAIEPLPFEDCLCQMLDLVKPENPGKITLRDLKRCRMSHIFFDTFFNIEKYLDHEQRDPLLAARDAEAVGQEISDWERYAAEEYDNLVAEETANEQYHDGYDNILDPADHVTSALELHSEKRHLFGIPSPHCNLDLDEYEYEDDFE", "length": 583, "header": "tr|B0S5T6-1|B0S5T6_DANRE Isoform 1 of Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta isoform X1 OS=Danio rerio OX=7955 GN=ppp2r3b PE=1 SV=1 CANONICAL=B0S5T6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 129, "start_aa": "Thr", "end_pos": 129, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr129", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 372, "start_aa": "Thr", "end_pos": 372, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr372", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:566032", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566032", "resource": "KEGG Pathway" }, { "id": "R-DRE-113501", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-113501", "resource": "Reactome", "description": "Inhibition of replication initiation of damaged DNA by RB1/E2F1" }, { "id": "R-DRE-69231", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-69231", "resource": "Reactome", "description": "Cyclin D associated events in G1" }, { "id": "R-DRE-69273", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-69273", "resource": "Reactome", "description": "Cyclin A/B1/B2 associated events during G2/M transition" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XGQ7-1", "protein_name": "Protein phosphatase 2 regulatory subunit B''beta", "gene_name": "PPP2R3B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPPGKVLQPVLKMKVDELFLCWLSQPTTQVMLKDCLRKIKNEEKTEIGNGDAGNSENERFTTKNSNSKQSTLGDIRLPLMPFTPPQLSTSLPSATSTSLRSVSNVKGTRRSSGTRVVQTKKEETLPPSLSQTIPTFYFPRGCPKEKVNIDAVIAKIERTFSQFPNERATLDDMGKVAKACDCPLYWKGPLFYCAGGERTGYVSVHKFVAMWRKILQTCYDDAAKFVHLLMNPGCNYLVQEDFIPFLQDVVNSHPGLSFLKEASEFHSRYITTVIQRIFYTVNRSWSGKITCNELRKSNFLQNVALLEEEADINQLTEYFSYEHFYVIYCKFWELDTDHDLYIDRKDLARHNDHAISSRMIERIFSGAVTRGRKAQKDGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMYELEYFYEEQCQKLDNMAIEPLPFEDCLCQMLDLVKPQYEGKITLHDLKRCKLTNVFFDTFFNIEKYLDHEQKDQFSILRDSEGESPEVSDWEKYAAEEYDILVAEEAASDQWNDGYEAELNPVDHQKANVLKYQMEKRPFFEMPSHLADVDLDEYDYEEDFE", "length": 581 }, "evidence": [ { "id": "B0S5T6", "url": "https://omabrowser.org/oma/group/B0S5T6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZLD7-1", "protein_name": "Protein phosphatase 2, regulatory subunit B'', alpha", "gene_name": "Ppp2r3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPVSQFKDVDLNSVFLSHENGLSSAEDYPHQALTGIPRSKRASTFQNTCNLKDIAGEAISFASGKIKEFSLEKLRNSNHAAYKKGRKVKSDSFNRRSVDLDLLCGHYSNDGTSPSFGLLRSSSVEEKSLSHRNSLDTSLTSMLFQNLSEEDLVTQILEKHKIDHFSSGTDIKMCLDILLKCSEDLKKCTDIIKQCIKKKSGGSINEGSGSDAMSNSETVYMNVMARLAYYLRKLPFEFVQSGSNETVDLTELVNNVPNLQLTPFSPLYGTEQPPKYEDIVHLSALDSRQFQTVELQDDMHNFKQTDTVKTPPNNTNSLCSLEVNDPGTLKPVQLQSPSLTINHLENVSSGNLMETLYIEEESDGKKSLLDKGQKADNGQGQEPLKVNEHKEFSDHDTYLKKCPAPVQNEISKIFEKPMVVRPPKEESELAVPPTELRAQRHFMNPNSQEEIDKLLMDLESFSQKMETSLGEPLAKGKSINSLNSHSHLTGQIHKDLEPKPIVSSATEKVSPSCLTRIIENNGHKIEEEDRALLLRILESIEDFAQELVECKSSRGSLSQEKEMMQILQETLTASSQPTPSVSRSPVGEKPKDSTSVVLIQQTPEVIKIQNKPEKKPATPCPPAATLPSSPQPASPVPCVSDVVNTPLSINIPQFYFPEGLPDTCSNHEQILGRIEAAFKDIEDQKADIHEMGRIAKACGCPLYWKAPMFRAAGGEKTGFVTAQSFMAMWKKLLSDHHDDASRFIWLLAKPSCSHLQQEDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVVQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHFYVIYCKFWELDGDHDLYISQADLSRYNDQASSNRIIERIFSGAVTRGKTVQREGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPANDGRITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENEGPEPSDWDRFAAEEYEALVTEESAQVQLQEGSFEDYESDEPVSPSELGNKGNKILTSSLSEKCGKLQSVDEE", "length": 1150 }, "evidence": [ { "id": "FB:FBgn0038744", "url": "https://alliancegenome.org/gene/FB:FBgn0038744#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QG28-1", "protein_name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X1", "gene_name": "ppp2r3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAATYRIVVSSINCYNSVVIDRRVQHTVHYCNGPCGALKHGLNCTVAHRSTCAELLDTSISRTCSERPINLHESKTIENGNTGPVAFCDDYHQVIPRVKKGSAIQSSASLKDITGEAINLASGKIKEFSFEKIKYSSSHVTFRKGRKVRPDSFSRRSTDLDIIYGQFTGNDENCPPFGLFQKSVLEEHKLSRSASLEQNLNNVATLYLNSLTEENLITRILEKTKADSSASGEDIKACLDILLKCSEDLKKCTDIIKQCIKRKSMGGTSDDSGNPEIIYKNVMARLSNYLKRLPLELEQGQSIRQEHSELAELVNSIHGLQQIPFSPIFGNEQPPRYEDVVQSPPPTKPRNKPSQPEPSEGSRELTGSLKPIQSVPGLSARTPPSTNGFSHGSLPTASSSSSTPFICQHTVSTSRPDTFSSANSFLSISNENLCKDPMEALYIEEEDSDIGRMPDRPVKGDGKHSCNLSESRQYSKRTTGYSEPSGGVSDKLHELSRNGTTFKPQNDSTVNQMYLPKSTDSKLFSRSTSHTSKGGADDIDKLLMDLECLSQNMQKEPPLPPKLKNCALQTSSPQHLIGNSVVKDLPVVGFSGPSVAKPPEPGVESTEEDDGALLLRILESIESFAQELVESGAGRGTQTKEREVMRLLQETLASTKAEVTPLPLPESETAPSPPQTPQCKPASTLSNTPTAIQIPASTLRDTGSTLLIQQTPEVIRIQPEKKPGTPPPTLSPAPSSPTPRPPSPPPAKVVATPPPSSINIPRFYFPKGLPNCAANYDEAIAKIEAAFTEFEEEKADIYEMGKIAKACGCPLYWKSPMFICAGGERTGFVSVHSFIATWRKLLHSCYDDASKFVYLLAKPGCTYLEQEDFIPLLQDIVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWTGKINMTELRRSNFLQTLALLEEEDDINQITDYFSYEHFYVIYCKFWELDSDHDLFIDPKDLARYNDHASSSRIIERLFSGAVTRGNSVQREGRMSYAEFVWFLISEEDKKNPTSIEYWFRCMDMDGDGVLSMFELEYLYEEQCERMEGMGIEPLPFQDLLCQMLDLVKPECPSKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDLDSDGPEPSDWDKYASEEYEILVAEETANEQLREGSFDDDYESDELTVSSDIGNKMDKLVISDLSA", "length": 1192 }, "evidence": [ { "id": "FB:FBgn0038744", "url": "https://alliancegenome.org/gene/FB:FBgn0038744#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0R7K2-1", "protein_name": "Protein phosphatase 2, regulatory subunit B'', beta", "gene_name": "Ppp2r3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPRKPPPSPLRPCLQMKVDELFLRWLSDPGTQRALRAGLRRIQGPAVILDHTVTPNPATALDSATKAIAAPAKIAPPDPAVTPNPAAIASSTAITKFSASRKRNRHRAVPPRGEEPGPKAPLPGRGIPAFYFPRGRPGQGPDVDDVIADVERAFARLPSGRAGLQDMGVVAKACCCPLYWKAPLFLAAGGGAQGGFVSARDIIGLWKPILLTCHDEAARFERLLGGPGDGGLSPEDLAPLVQDVADSHPGLSFLREAEPLRRDYVTTVTQRVFYAVNRSWSGRISCQEIRRSCFLQAVSQLEAEPNPGRATPSFFSYPHFCVIVSKFQALDADGDGLIDRHDLRRHADGAISSRMIDRIFSGAVTRARPSPEGGKMGLADFVWFLLSEEDKTTPTSTEYWFRCMDLDGDGVLSAPELSFFYEEQAQNLAARGAEPPPFADLTRQALDLVQPRCPGQITLGDLKRCGLAGEFFDAFFNADKFLEHERREPAGPVRAPDADPTLSDWDRFAAAEYDFLLAEEAQDDDAWEEGPSPRSESPPSSPDPYDFADDTLDPL", "length": 556 }, "evidence": [ { "id": "RGD:1588134", "url": "https://alliancegenome.org/gene/RGD:1588134#orthology", "database": "AGR" }, { "id": "HGNC:13417", "url": "https://alliancegenome.org/gene/HGNC:13417#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-268", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-268#orthology", "database": "AGR" }, { "id": "MGI:1335093", "url": "https://alliancegenome.org/gene/MGI:1335093#orthology", "database": "AGR" }, { "id": "FB:FBgn0038744", "url": "https://alliancegenome.org/gene/FB:FBgn0038744#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q06190-1", "protein_name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha", "gene_name": "PPP2R3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATYRLVVSTVNHYSSVVIDRRFEQAIHYCTGTCHTFTHGIDCIVVHHSVCADLLHIPVSQFKDADLNSMFLPHENGLSSAEGDYPQQAFTGIPRVKRGSTFQNTYNLKDIAGEAISFASGKIKEFSFEKLKNSNHAAYRKGRKVKSDSFNRRSVDLDLLCGHYNNDGNAPSFGLLRSSSVEEKPLSHRNSLDTNLTSMFLQNFSEEDLVTQILEKHKIDNFSSGTDIKMCLDILLKCSEDLKKCTDIIKQCIKKKSGSSISEGSGNDTISSSETVYMNVMTRLASYLKKLPFEFMQSGNNEALDLTELISNMPSLQLTPFSPVFGTEQPPKYEDVVQLSASDSGRFQTIELQNDKPNSRKMDTVQSIPNNSTNSLYNLEVNDPRTLKAVQVQSQSLTMNPLENVSSDDLMETLYIEEESDGKKALDKGQKTENGPSHELLKVNEHRAEFPEHATHLKKCPTPMQNEIGKIFEKSFVNLPKEDCKSKVSKFEEGDQRDFTNSSSQEEIDKLLMDLESFSQKMETSLREPLAKGKNSNFLNSHSQLTGQTLVDLEPKSKVSSPIEKVSPSCLTRIIETNGHKIEEEDRALLLRILESIEDFAQELVECKSSRGSLSQEKEMMQILQETLTTSSQANLSVCRSPVGDKAKDTTSAVLIQQTPEVIKIQNKPEKKPGTPLPPPATSPSSPRPLSPVPHVNNVVNAPLSINIPRFYFPEGLPDTCSNHEQTLSRIETAFMDIEEQKADIYEMGKIAKVCGCPLYWKAPMFRAAGGEKTGFVTAQSFIAMWRKLLNNHHDDASKFICLLAKPNCSSLEQEDFIPLLQDVVDTHPGLTFLKDAPEFHSRYITTVIQRIFYTVNRSWSGKITSTEIRKSNFLQTLALLEEEEDINQITDYFSYEHFYVIYCKFWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYADFVWFLISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQMLDLVKPAVDGKITLRDLKRCRMAHIFYDTFFNLEKYLDHEQRDPFAVQKDVENDGPEPSDWDRFAAEEYETLVAEESAQAQFQEGFEDYETDEPASPSEFGNKSNKILSASLPEKCGKLQSVDEE", "length": 1150 }, "evidence": [ { "id": "FB:FBgn0038744", "url": "https://alliancegenome.org/gene/FB:FBgn0038744#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QIT3-1", "protein_name": "Serine/threonine protein phosphatase 2A regulatory subunit B''beta", "gene_name": "B''BETA", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVDTVIPGDMACLDADLLQLQEMSSFVLNSKPGFTQKLFDQWLSLPEAQRQVGSLLKDAVAGAPINVTGSASGSNSATIPSMFPAGSAPPLSPRSCGSPRTTKQRAPSNLGSTLKVVNEPVKEPIPQFYFQNGRPPPSEIKEQCMFRINHFFYGHMDGLQIQEFKLVTREICKLPSFFSTSLFRKIDLNNTGFVTRDAFIDFWVNGNMLIMDTTTQIFKILKQKDQSFIVKDDFKPLLKELLATHPGLEFLQSTPEFQERYAETVTYRIFYYINRSGNGRITFRELKRGNLIDAMLHADEEEDINKVLRYFSYEHFYVIYCKFWELDTDHDFLIDKENLMRYGNHALTYRIVDRIFSQVARKFTSKVEGKMGYEDFVYFILAEEDKSSVPSLEYWFKCIDLDANGIITRNEMQFFYEEQLHRMECMAQEAVLFEDILCQMIDMIGPENESHITLHDLKGSKLSGNVFNILFNLNKFMAFETRDPFLIRQERENPTLTDWDRFAHREYIRLSMEEDVEDASNGSAEVWDDSSLEAPF", "length": 536 }, "evidence": [ { "id": "B0S5T6", "url": "https://omabrowser.org/oma/group/B0S5T6/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9I7J1-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "PR72", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQANSSTTTTTTTTKTKKLSSGTGTNMISSVAVTSAIKTTTTTRKPAGSGVSSKVSKAQGATNSTPASSDSNAEIAELTKKINDHADAIYHTWKSQGIPPTELLTMYTSAAASGDLADVASPTADAEGLQKMVTSFVNKDKEQRGKSNTLKKSDITTANGKVKKAAVSSFSPVPDQALQSPKKVAAVTVSKPLPDVNLNYDISLDLDVNNLSSQQTQNLLKISELIQQQKDVAATVGKKRQNSKANSSSSINSNHIGNSASSNKLTASEQPTKKQSKANSSGSTRTGSAAVSLDVVDGPSAARIANSTAVSDKGGEPAATGSRKSSKTKETSADSKPATKEKPTAVATVANARKSTSRIATDNAGNMAAATAAAAATSATSAATATSMDATPATAASTTMPTLNKVKPTSGARAALANGQDKMNLLTRGSVAERVLMFEKCPDVRHAFLNIKRPQTDPPPKSLMKVKLHATPPPPPQEQNLLQKEIRSTKSVYIPRFYFPHGKPQPNIAMERVVRGILSAFDSFPNNQVTKDELPRILKICGLPFYWRMPVMVFCQSASTGLVERQRFVEFWKQMNVYCHEAASRFVYILSRGQRFRSYIVPEDLVPMVQDVVDTHPGLAFLKEATEFHSRYVHTVIARIFYSVNRSWSGKITIAELKRSDLLEMISLLEEEEDINQIMAFFSYEHFYVIYCKFWELDKDHDLLINQEDLAKHSDHALSSRIVERIFSGCVTRSDNKKAPEDEAKMSYTDFVWFILSEEDKRTPTAIEYWFRCMDVDGDGVLSMYELEYFYEEQQQRMEGIGIECLPFEDCLCQMLDMIKPANRDCITLGDLKRCKMTHVFFDTFFNLEKYLDHEQRDPFASQRDEYTSDWDRFAAQEYELLISEEND", "length": 888 }, "evidence": [ { "id": "RGD:1588134", "url": "https://alliancegenome.org/gene/RGD:1588134#orthology", "database": "AGR" }, { "id": "HGNC:13417", "url": "https://alliancegenome.org/gene/HGNC:13417#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-268", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-268#orthology", "database": "AGR" }, { "id": "MGI:1335093", "url": "https://alliancegenome.org/gene/MGI:1335093#orthology", "database": "AGR" }, { "id": "FB:FBgn0038744", "url": "https://alliancegenome.org/gene/FB:FBgn0038744#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y5P8-1", "protein_name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta", "gene_name": "PPP2R3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPGKVLQPVLKMKVDELFLYWLSEASTQRMLQDCLRRIKAPGRDQPTPGDGEQPGAWPTAPLAAPRPSGLEPPGTPGPGPALPLGAASSPRNAPHVRGTRRSAGTRVVQTRKEEPLPPATSQSIPTFYFPRGRPQDSVNVDAVISKIESTFARFPHERATMDDMGLVAKACGCPLYWKGPLFYGAGGERTGSVSVHKFVAMWRKILQNCHDDAAKFVHLLMSPGCNYLVQEDFVPFLQDVVNTHPGLSFLKEASEFHSRYITTVIQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEEEADINQLTEFFSYEHFYVIYCKFWELDTDHDLLIDADDLARHNDHALSTKMIDRIFSGAVTRGRKVQKEGKISYADFVWFLISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQMLDLVKPRTEGKITLQDLKRCKLANVFFDTFFNIEKYLDHEQKEQISLLRDGDSGGPELSDWEKYAAEEYDILVAEETAGEPWEDGFEAELSPVEQKLSALRSPLAQRPFFEAPSPLGAVDLYEYACGDEDLEPL", "length": 575 }, "evidence": [ { "id": "RGD:1588134", "url": "https://alliancegenome.org/gene/RGD:1588134#orthology", "database": "AGR" }, { "id": "HGNC:13417", "url": "https://alliancegenome.org/gene/HGNC:13417#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-268", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-268#orthology", "database": "AGR" }, { "id": "MGI:1335093", "url": "https://alliancegenome.org/gene/MGI:1335093#orthology", "database": "AGR" }, { "id": "FB:FBgn0038744", "url": "https://alliancegenome.org/gene/FB:FBgn0038744#orthology", "database": "AGR" }, { "id": "B0S5T6", "url": "https://omabrowser.org/oma/group/B0S5T6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z176-1", "protein_name": "Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit delta", "gene_name": "Ppp2r3d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPERPPIRALRRDPDDPAVAQALASLARGSDLVFPSRFQKWLRDFRQVHAHRKEEPPPQSPPPGHTVPAFYFPCGRPPPRPQDTEDAIALVECAFEGLPRGRAGLGDMAVVAKACGCPLYWKAPLFYAAGGERTGSVSVHMFVAMWRKVLLTCHDDAARFVRLLGHPGCSGLIQEDFVPFLQDVVNSHPGLAFLRAAKDFHSRYITTVIQRIFYTVNRSWSGMISREELRRSSFLQAVSQLEVEPDINRMTSFFSYEHFYVIYCKFWELDLDRDLTIDRSDLARHGDGAISSRMIDRIFSGAVTRARLPRKVGKLSYADFVWFLLSEEDKTTPTSTEYWFRCMDLDGDGALSMFELEFFYEEQAQRMAARGVEPLPFHDLARQVLDLVAPRCPGRITLRDLKQCGLAGEFFDAFFNVDKYLAREQREQAGTPQDTDSDPAASAWDRYAAEEYDFLVAEEAMAEDDDDHDEGSDPIDLYGLADEDCDDLEPL", "length": 491 }, "evidence": [ { "id": "RGD:1588134", "url": "https://alliancegenome.org/gene/RGD:1588134#orthology", "database": "AGR" }, { "id": "HGNC:13417", "url": "https://alliancegenome.org/gene/HGNC:13417#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-268", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-268#orthology", "database": "AGR" }, { "id": "MGI:1335093", "url": "https://alliancegenome.org/gene/MGI:1335093#orthology", "database": "AGR" }, { "id": "FB:FBgn0038744", "url": "https://alliancegenome.org/gene/FB:FBgn0038744#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "B0S5T6", "url": "https://www.uniprot.org/uniprotkb/B0S5T6" } ], "pmid": "" }, { "name": "protein phosphatase regulator activity", "id": "GO:0019888", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019888", "evidence": [ { "database": "UniProtKB", "id": "B0S5T6", "url": "https://www.uniprot.org/uniprotkb/B0S5T6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "B0S5T6", "url": "https://www.uniprot.org/uniprotkb/B0S5T6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "protein phosphatase type 2A complex", "id": "GO:0000159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000159", "evidence": [ { "database": "UniProtKB", "id": "B0S5T6", "url": "https://www.uniprot.org/uniprotkb/B0S5T6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0S5T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S5T6" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 399, "end_pos": 434, "start_aa": "Lys", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 129, 372 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 285, "end_pos": 287 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", 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"site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A5WVZ0-1", "uniprot_ac": "A5WVZ0", "uniprot_id": "A5WVZ0_DANRE", "mass": { "chemical_mass": 73386.0, "monoisotopic_mass": 73386.0 }, "refseq": {}, "gene_names": [ { "name": "cerk", "type": "recommended", "evidence": [ { "id": "A5WVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0" } ] }, { "name": "si:ch211-162i19.1", "type": "synonym", "evidence": [ { "id": "A5WVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0" } ] } ], "protein_names": [ { "name": "2.7.1.138", "type": "synonym", "evidence": [ { "id": "A5WVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0/entry#names_and_taxonomy" } ] }, { "name": "Ceramide kinase", "type": "synonym", "evidence": [ { "id": "A5WVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WVZ0", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cerk", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041210-210", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-210", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000069169", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000069169", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00303", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00303", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01647", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01647", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "558496", "url": "https://www.ncbi.nlm.nih.gov/gene/558496", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001995", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001995", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021109", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021109", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045363", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045363", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558496", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558496", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M2BGH4", "url": "https://www.orthodb.org/?gene=A0A8M2BGH4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A5WVZ0", "url": "https://www.orthodb.org/?gene=A5WVZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12358", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12358", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12358:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12358:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24559", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24559", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24559:SF455", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24559:SF455", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00781", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00781", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13975", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13975", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19280", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19280", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-9840309", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9840309", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001099056", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001099056", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BGH4", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BGH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BGH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BGH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J773", "url": "https://www.uniprot.org/uniprotkb/A0AC58J773", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J773-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J773-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WVZ0", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WVZ0-1", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041210-210", "url": "https://zfin.org/ZDB-GENE-041210-210", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649, "header": "tr|A5WVZ0-1|A5WVZ0_DANRE Isoform 1 of Ceramide kinase OS=Danio rerio OX=7955 GN=cerk PE=4 SV=1 CANONICAL=A5WVZ0-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BGH4-1", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0/entry#A0A8M2BGH4-1", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQCSEHSLCLLWIQTIKEQLALLTNRPKSLLVYINPYGGKQRGKQIYDHKVAPIFSRASISTDVIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYACCQLNNPPNHEL", "length": 563, "header": "tr|A0A8M2BGH4-1|A5WVZ0_DANRE Computationally mapped isoform of Ceramide kinase OS=Danio rerio OX=7955 GN=cerk PE=4 SV=2 CANONICAL=A5WVZ0-1" }, "locus": {} }, { "isoform_ac": "A0AC58J773-1", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0/entry#A0AC58J773-1", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQCSEHSLCLLWIQTIKEQLALLTNRPVEKQPIQCWRCSGPHPPGNCPMYLTPPSQQSSTQHHPNHGKSFHAAKSGGRPTNIIVAASETPQSTKEVPNVFLPSTTMSSLAIPQQLVVPISIGSWFGKAILDTGASYTLIHESLMQNFDTSAQLQNWSSGPLYLANGKAEIPLGWLNITIQIHGKSFVVPAVVLPSQALAYAIILGLDFIFFSGLKIHVSEHKYSFTSDPTEEHPFQPGYASEPLVKMTPMTEKKTLRKNKLNLTLLSAVPPPQTSLGMLQTDHVDDATQIWNAVSEAQLPKEEKQQLLQILQNNPRVCTQRTGKTKLLQHRIYTTSQVPIKQKPYRLSPVKQQVMEEQLEQMLRDGIVEPSHSSWASPVVLVPKKNGKLRFCVDYRKVNAITENDAYPLPNITEILESLSGSTIFFYHRFKQWVLASDDGS", "length": 553, "header": "tr|A0AC58J773-1|A0AC58J773_DANRE Computationally mapped isoform of Ceramide kinase isoform X2 OS=Danio rerio OX=7955 GN=cerk PE=4 SV=1 CANONICAL=A5WVZ0-1" }, "locus": {} }, { "isoform_ac": "A5WVZ0-1", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0/entry#A5WVZ0-1", "sequence": { "sequence": "MEKQSTLLCSELSVQRRLYEVTLNCAILAWKDVQNAKKHTGRAIYGAVKAGSHCVPVCEIIAVQEKEDDSPCKDTGKWQKVPQSPTDSCQHAFTVYYVERTRQHCWRCSNVTFQYSEHSLCLLWIQTIKEQLALLSAQSTEELAGVHQPLRRKTTRQADLRPQSGPHLFPGFHFHRRDWPHSFSAHPSELRFYIIADGKEPVMKCTGDCFSPRVQLHHLMQLIDGLHQASRKMQFNCQMNIMMFLPPLYHQPGNNGFSLFVSIVTEHANHARDHLKAEADLKKYDGVVCVGGDGMFSEIMHGLVSRTQQDAGVDENSTEETLIPCGLRIGIIPAGSTDCICYATVGSNDPVTSALHMVVGDSQPMDVCSVHSDDRFLRYSVSLLGYGFYGDVLKDSERKRWMGPARYNISGVKTFLSHRYYEGTVSFLPAEENLGTPRDKVQCRSGCSICRRSSSDKLLSKEDEASVSDVDCRDTWTVIRGKFLAINAANMSCACPRSPKGLSPSAHLADGTTDLILVRKCSRVDFLRHLLRHTNKKDQFDHSFVEVYRVKQFRFTPRFQECGSEMDLRESRAGGKHFFCQICRENRACGCMSSQSNWNCDGEILPHTAIQVRVHCQLIKLFARGIEEQPVFEDLYAHCQLNNPPNHEP", "length": 649, "header": "tr|A5WVZ0-1|A5WVZ0_DANRE Isoform 1 of Ceramide kinase OS=Danio rerio OX=7955 GN=cerk PE=4 SV=1 CANONICAL=A5WVZ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A5WVZ0", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A5WVZ0", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Immune gene variation associated with chromosome-scale differences among individual zebrafish genomes.", "journal": "Sci. Rep.", "date": "2023", "authors": "McConnell Sean C, Hernandez Kyle M, Andrade Jorge, de Jong Jill L O", "evidence": [ { "database": "UniProtKB", "id": "A5WVZ0", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0" } ], "reference": [ { "type": "PubMed", "id": "37179373", "url": "https://glygen.org/publication/PubMed/37179373" } ] } ], "pathway": [ { "id": "dre:558496", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558496", "resource": "KEGG Pathway" }, { "id": "R-DRE-9840309", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9840309", "resource": "Reactome", "description": "Glycosphingolipid biosynthesis" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A075B5S0-1", "protein_name": "Immunoglobulin heavy variable 16-1", "gene_name": "Ighv16-1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "EVQLVESGGSLGQPGGSTKLSCEEASGFTFSDHWMDWFRQAPGMRLEWLANTNHDESGKGYAESVKDRFSISRDNSENLLYLQMNSLRNEDTALYYCAR", "length": 99 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B603-1", "protein_name": "T cell receptor alpha variable 6D-6", "gene_name": "Trav6-6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSPGFVAVILLILGRTHGDSVTQTEGPVTVSESESLIINCTYSATSIAYPNLFWYVRYPGEGLQLLLKVITAGQKGSSRGFEATYNKETTSFHLQKASVQESDSAVYYCALG", "length": 114 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B625-1", "protein_name": "T cell receptor alpha variable 4N-3", "gene_name": "Trav4n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERNLGAVLGILWVQICWVSGDKVKQSPSALSLQEGTNSALRCNFSIAATTVQWFLQNPRGSLMNLFYLVPGTKENGRLKSAFDSKESYSTLHIRDAQLEDSGTYFCAAE", "length": 110 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B695-1", "protein_name": "T cell receptor alpha variable 9D-3", "gene_name": "Trav9d-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLALLPVLGIHFLLRDAQAQSVTQPDARVTVSEGASLQLRCKYSYFGTPYLFWYVQYPRQGLQLLLKYYPGDPVVQGVNGFEAEFSKSNSSFHLRKASVHWSDWAVYFCAVS", "length": 113 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6B4-1", "protein_name": "T cell receptor alpha variable 6-4", "gene_name": "Trav6-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTSPVLVTVMLLFMLGMRKTHGDSVTQKQGQVTLSEDDFLFINCTYSTTTYPTLLWYVQYLGQGPQLLLKVTTANNKGISRGFEATYDKGTTSFHLQKASVQESDSAVYFCALV", "length": 115 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B6D8-1", "protein_name": "T cell receptor alpha variable 3-3", "gene_name": "Trav3-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "GEQVEQRPPHLSVREGDSAVITCTYTDPNSYYFFWYKQEPGASLQLLMKVFSSTEINEGQGFTVLLNKKDKRLSLNLTAAHPGDSAAYFCAV", "length": 92 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A075B759-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4E", "gene_name": "PPIAL4E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A075B767-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4H", "gene_name": "PPIAL4H", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFDITVDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTDDKSIYGEKFDDENLIRKHTGSGILSMVNAGPNTNGSQLFICTAKTEWLDGKHVAFGKVKERVNIVEAMEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WP50-1", "protein_name": "Secretoglobin, family 1B, member 15", "gene_name": "Scgb1b17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMLAGAVVIFGVALLLLSSWGDCGICPAMKEDVHLFLNGTSEEYVEYVKQYKDDPEILENTEKIKQCVDSTLMEEDKAHANGFIEKIEASPLC", "length": 93 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPA9-1", "protein_name": "Secretoglobin, family 2B, member 18", "gene_name": "Scgb2b18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQSCYSEERIRNILLEPKIMEAMVASPECRSYHSFNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPG5-1", "protein_name": "Predicted gene 13283", "gene_name": "Gm13283", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLADLRSVPGHQCLRDRTDFPCPWKEGTNITQMTLGETTSCYSQSLRQVLHRFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WPY7-1", "protein_name": "RNA binding motif protein Y-linked family member 4", "gene_name": "Rbmyf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKR", "length": 166 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQA9-1", "protein_name": "Secretoglobin, family 2B, member 21", "gene_name": "Scgb2b21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACVPFFEGYASVVSGSRVWMYQEFQAFDATAEEKVALEKIQGCYREESLRNILLEPKIMEAMVASPECLSYYSSNNIRCILDLLSKLLGQ", "length": 112 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQJ0-1", "protein_name": "Secretoglobin, family 1B, member 11", "gene_name": "Scgb1b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLVAAVVILGAALLLLTSGGDCGICPAIKEDVRLFLNGTSEEYVEYVKQYKDDPVILENTAKINQCVDSTLTEKDMTHTTTFLKKIEDSLLC", "length": 93 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WQP8-1", "protein_name": "Predicted gene, 21698", "gene_name": "Gm21698", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHGQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR36-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r90", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNEAMKTTEEVALQIVLLCQFGIGTMANILLFIHNFSPLLTGCQLRPKQVICTNMAVSSILILFMTVFPNNVFVVQRNLMNDLQCKLEYFLRMVARSINLCSTCVLSTYQFVTLLPGNFGEMMVRGRRSKVISYSCCSCWLFGVLYNVYIPMKVSGPQNTHNKTDIKSKWFCVTSGFSVGIMFLWFAHDAIFISIMIWTSVSMVLLLYRHYQRLQYIFPPHQGTRGYAEIRAAHSIAMLVVTFVSFYLLHCICFILHIVFVDSRLWLRHVGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYRKPVI", "length": 309 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR44-1", "protein_name": "BTB domain containing 35, family member 15", "gene_name": "Btbd35f15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WR49-1", "protein_name": "Secretoglobin, family 2B, member 11", "gene_name": "Scgb2b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTSEACVSFFEGYASVLSGSRVWLYQELQAFDATAEEKVALEKIQGCYSEERIRNILLEPKIMEAMVASPECRSYHSLNNFRSILEFISNLLGE", "length": 112 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSM5-1", "protein_name": "Predicted gene 29049", "gene_name": "Gm29049", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSLKKKSRRKPSSQALGNIVGCRISYGWKEGNEPVTHWKAIILGQLPTNPSLYLVKYDGIDSVYGQELHSDERILNLKVLPHKVVFLQVRDVHLASALVCREVQHKFEGKDGSEDNWSGMVLAQVPFLQDYFYISYKKDPVLYVYQLLDDYKEGNLHIIPETPLAEARSGDDNDFLIGSWVQYTRDDGSKKFGKVVYKVLANSTVYCIKFLGDLHIYVYTLVSNIT", "length": 227 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSN2-1", "protein_name": "BTB domain containing 35, family member 16", "gene_name": "Btbd35f16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLLFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLNFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WUL8-1", "protein_name": "NBPF family member NBPF19", "gene_name": "NBPF19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLFHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELVEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSIPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQCVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDPLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEEHISFALYLDNRFFTLTVTSLHLVFQMLVIFPQ", "length": 3843 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087WXS9-1", "protein_name": "TBC1 domain family member 3I", "gene_name": "TBC1D3I", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKMKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A087X179-1", "protein_name": "TBC1 domain family member 3E", "gene_name": "TBC1D3E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDQAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKKSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0A0MQP3-1", "protein_name": "BTB domain containing 35, family member 12", "gene_name": "Btbd35f12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDSDLSITPLEVPQGLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YW58-1", "protein_name": "Immunoglobulin heavy variable V8-2", "gene_name": "Ighv8-2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRLTFSFLLLLPVPAYVLSQVTLKVSGPGILQPSQTLSLACTFSGISLSTSGMGLSWLRKPSGKALEWLASIWNNDNYYNPSLKSRLTISKETSNYQVFLKLTSVDTADSATYYGAWR", "length": 119 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXW2-1", "protein_name": "Predicted gene, 20773", "gene_name": "Gm20773", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKIFKVEKS", "length": 232 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0A6YXX7-1", "protein_name": "Predicted gene, 20807", "gene_name": "Gm20807", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVGCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHTFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKVLEVEKS", "length": 232 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0B4J1J8-1", "protein_name": "T cell receptor gamma, variable 4", "gene_name": "Trgv4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNPGSQALLPLYLPWEANLADENPLLKVVIFLCLLTFGHGKLEQPEISISRPRDETAQISCKVFIESFRSVTIHWYRQKPNQGLEFLLYVLATPTHIFLDKEYKKMEASKNPSASTSILTIYSLEEEDEAIYYCSYG", "length": 138 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JE01-1", "protein_name": "Predicted gene, 21663", "gene_name": "Gm21663", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADPPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JGR8-1", "protein_name": "Predicted gene, 21680", "gene_name": "Gm21680", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPSESNEGRRRWTWRMWMAHRQTTSPVPVTSKKQFEKEEKELIKKIQLTTKEINELRDRLIYVTKGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELVLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A0G2JMD5-1", "protein_name": "PRAME family member 33", "gene_name": "PRAMEF33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLQAPSRLLELAGQSLLRNQFLTIFTLDELPREVFPLMFMEAFSMRRFEALKLMVQAWPFLRLPLGSLMKTPHLETLQAVLRGLDTLVAQKVRPRRWKLQVLDLQDVDENFWTIWSGARVLSCSPEAMSKRQTVEDCPRMGEHQPLKVFIDLCLKESTLDECLSYLFGWIHYRRGLVHLCCSKVQNYSMPTSSFRNLLERIYPDSIQELEVWKKCSLNKTGKFAPYLSQMSNLRELFLAFGYERELYVSVQWPCIPDLDSPFLCLYYPQMLYIKKISNIKEHLEHLLRYLKNPLGAFIFSDAYLADRDMECLSQYPSLSQLKELRLIHILMWTTNLQPLGALLEKVAATLKTLVLKDCRIQDPQLRVLLPALSHCSQLTTFNFHGNETSMNALKDLLRHTRGLSKLGLELYPAPLESLDYKGHVNWEILTPIRAELMRTLREVRQPKRIFFGPVPCPTCGSWPSEKVDFHLCS", "length": 474 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JNH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC124905359", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIANNTVVTEFILLGLTQSQDIQLLVFVLILIFYLIILPGNFLIIFTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFFSEKKVISYRGCITQLFFLHFLGGGEGLLLVVMAFDRYIAICRPLHCSTVMNPRACYAMMLALWLGGFVHSIIQVVLILRLPFCGPNQLDNFFCDVRQVIKLACTDMFVVELLMVFNSGLMTLLCFLGLLASYAVILCHVRRAASEGKNKAMSMCTTRVIIILLMFGPAIFIYMCPFRALPADKMVSLFHTVIFPLMNPMIYTLRNQEVKTSMKRLLSRHVVCQVDFIIRN", "length": 316 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTV6-1", "protein_name": "RIKEN cDNA 4931429L15 gene like", "gene_name": "4931429L15Rikl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFNPFSQDTWRHGHRRAYSNISERLSCLTLQEPSVSHLYQIFSPGDRRSYLLDDSLSNSIQRESLAVPMGLEDSGSRGQQKQQQPGAVLEDLEEQEIAPTDVKYRLQLLDEAPLRSKSSSVQSQGHKPGWIPSSKTHREWFKPWKMDMTYPENERSHSGHTQGRRMTPRAQWRHVEYDSQDQDTQSPVWSQALFPGLDKSSQGVIQCTQHVSREREMVSGWSMTHAPQEMGQAKQGPAFLKTKGTAKFNVATTARMSCLPPLKLLEKKVKSRCPPNTPGIFQDWRAQPQGLYGSDERLLAPFEDQVNTRVTYMPLFTEKVKFVSPKTAVSNPKQTHSQLSRTNQPAFPGQFRNWTSGREHLEKGLPE", "length": 368 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JVP7-1", "protein_name": "40S ribosomal protein S26", "gene_name": "Rps26-ps4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKKRRNNGRTKKGRGHVQPIGCANCSWCVPKDKAIKKFVIWNIVETAAVRDISEARIFDAYVLPKLYVKLHYCVSLAIHSKVIRNQSHEARKDRTSPPRFRPAGAAPRPPPKPM", "length": 115 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW93-1", "protein_name": "High mobility group protein B4", "gene_name": "Hmgb4l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDSKVRPKVNVSPYVHFMMDFRNQTREQQPNTYYDFTEFSRKCSEKWKTISKKEKKKYEALAKRDKDRYQREMRNYSGPRRERRRRDPDAPRKPPSSFLLFSQDHFDEIKEQHPNWTVAQVAKAAGRMWARCSEADKIPYEERAAVLRAKYLEEREAYYHQCQRGE", "length": 168 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JW96-1", "protein_name": "Zinc finger protein 94 like 1", "gene_name": "Zfp94l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRGSCDVMLESLRNVASLGHRIGTPDGLLRLKREDMFWLLTVARWSSGSMGDKNLEDMEFLEEVGLRHLPHEELFCSQIWQRITRELTKVRDCRVRVGENGSPMKRDNREDEYSKHSSQNSVFQVHHRECHEEEANERDFGCSHHLRTSTGEKSYKCEKCHNASHWFSSLQSHQGVCDRPRWNKSVSQFKIFRQWPLFHYQQSMPNGENAQEYEACGNAGKNSSGQTALFVHTAEEPYSCEECGARFSQSSYLQVHQRVHTGEKPYKCEECGKGFGWLSQLHAHHQSHTGEKPYTCDACGKGFSYSSHLNIHCRIHTGEKPYQCEECGKGFSQASNLLAHQRGHTGEKPYQCDACGKGFSRISDFNIHIRVHTGEKPYKCEECGKGFSQASNLLAHQRGHTGEKPYKCNTCGKSFRRSSDLNVHCRIHTGEKPYRCEKCDKVFSQFSSLQVHQRVHTGEKPYQCSECGKGFSVGSQLQAHQRCHTGERPYQCEECGKGFCRASNFLAHHGVHTGEKPYRCDMCGKHFRQRSYLQAHHRVHTGEKQFRCEECGKGFSWSSYLQAHQRVHMGEKPYKCEECGKGFSWSSSLLTHQRVHAEDEGQKDLSSSGGSYRK", "length": 616 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYP5-1", "protein_name": "Olfactory receptor", "gene_name": "Or8g52b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEGNHSRVTEFILTGLTDKPELQLPLFLLFLGIYLLTVLGNLGMIILILLSSHLQTPMYFFLSGLSFIDLGYSTVIIPKMLVNFVTEKNVISYPGCMTQLYCFIAFVLCECYMLSAMAFDRYVAICNPLRYNVTMSYQVCFWMIGGVYSIGFIEATIHTVCMLQVFFCKANVVNHFFCDLLPLFQLACSSTFVNETVLLCLSTLNFCVPTLTILSSYSFIIARIIRIKSTESRFKAFSTCSSHFSSVAVFFGSLGFVYFQPSSVSSKDQGKVSSVFYTIIVPMLNPLIYSLRNKDVKLALNKLFQKKIFHM", "length": 312 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K381-1", "protein_name": "Killer cell lectin-like receptor, subfamily A, member 4", "gene_name": "Klra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQEVTYSTLRFHNSSGLQNQVKTNETQGPRETGHRGCSVSWHLIMIPLGILCSILLVTVAVLVTHIFQYSQEKHELQEALNKLHHNYSTMQNESYLNEEMLGNKSSECDAYKSVLDSLNRQQNTCLRLTNIVLDCLQHKGRQVNVHLFCCGIKCYYFIMDKKQWKECEQACQGCKLSLLTIDDEDELKFLQLQVTPDSYWIGLSYDNKKHDSAWIDNNPSKL", "length": 224 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K3S0-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNQSFVNEFILLGLSQNPQIKKISFVIFLLVYIATLVGNMMIVVTIAYSPALLGSPMYFFLAVLSFLDACVSSVVTPKMIVDMVYERKSISFECCMTQVFAVHFLTAVEVIVLAAMAYDRYVAICKPLHYSSIMNRRLCGTLVGVAWAGGFLHSIIQIAFTLPLPFCGPNVIDHFICDLFPLLKLACTDTHIFIILVFANSGSICIIIFSFLLISYGVILFALRAHSSEGRRKALSTCGSHITVVVFFFVPCILIYARPTSAFSFEKNVFVFTDVLTPLLNPMVYTFRNKEMINAIRKMWKRLIVVSDKY", "length": 311 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K622-1", "protein_name": "Histone RNA hairpin-binding protein", "gene_name": "Slbpl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLSSRMEMVSVGVTTEPCHARWEVETDEVVLRRRQKQIDYGKCTPGYQSFLQQVPRAQRQPGFHPQTPNKNRRYSRRSWDAQIRQWRRALHTWDPPSQPLHDRQAEGKAAGNFLRPVDTAPLDDLLDNWPQDPESSENWDRGEKEAQFAYLKVPASCPPQLKDELLHH", "length": 169 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K698-1", "protein_name": "Lamin tail domain containing 1", "gene_name": "Lmntd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHLASSHRVQKSSLARPERRAKSPSYTDISFWVPVMHRVGSQYQFESVCEQSSGYPGMPAQQVTPVPSQRGGILRKEEKTGTITPSKQHSSVHFFPKVMDSSSTLHLLSGSFSHEASANFHQIPSAQDSLSPGGLLTSKSNVPSCSRKDSIPGKQSTHQAASPGTSLMTLKKQPKPSSDLDTYVLGDGEDYFLSLFGDSKKLTSHTSQAEDVSKHLSVILEEVGQFVSSSLGDIKIAEVNVKGFFVRLVNSSNEKEVEIGNYILQQNVNGQAVSLYRFPHNITMQASGTVTVWAAASEAKPQQPTDFVWEEQSRFRSSPDCTTILCKPSGEAIAWYTPIHWKQAWEKLETDIEFERCSVVIPSLKSHIFGRTTSSVSSINKEKQEPTQKTPPQVCSVLLREKEILLTVLPNKSPWCRSPDTPPHPYSSLIEWHDSDFPGSSLGTQPKPQSTKPKPDPGTKEKKSTR", "length": 467 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6E6-1", "protein_name": "Rho GTPase-activating protein 20-like", "gene_name": "LOC120093152", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDEELVRANKTCTCKTIFFYWATGNALATFRSEEQKVQWYTFLTSRSISEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHKIEDYQLWFSPGHKEAPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERRRKSCMTSCFHGGCVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTKSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAVASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQAEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKMFYGRDLSKKLSIIQFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKANTKELEMSSAVPHEGGPTAGHNGTTSKYNVPQEIILHD", "length": 835 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K6V9-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVVFFLGQGSYGRVRLAWHRRTQALVAIKTVEISKDTIRGILSEMTTLESLNHPNIISLYEVLITGTGVHFILQYAPGGNLGKLISEEGPLPEEKAKKMFGQVVSAIRYCHSLDIVHRDIKPQNILIDGEGNIKLIDFGQAIKCKPGTLLSRHCGTRDFNAPELVLREPYDGKSSDVWSLGVVLYFFTTGYLPFRGKTINDVEERITTGTYTIPTHLSGQLENLIHQILRVSPDMRPSVEEIENHPWIKKCEFKILPKTDPDYKIIEMLCAMGYKAKDILESLQKKRYDEPMGAYLSLKDHVSKGFDVGYITPAKPGDPCPPPPPSPAHPSVFGLPLRRRASEPIFGLHHRPPSREQNPLDLILSGLKMSRCVSMPPIAVYYPKKERSTSTRALHSTPVACPCVSNNMSEVEIILPPKQDIEMNTSSPPQRMGWFKRLRKGIRDCFSRLCCLPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K894-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAHLLNVTEFIFLGLSPNKEGQRVCFVLFLLLYMAIVLGNLLMVVTVAASRNLGSPMYFFLSFLSFVEICYSSTTAPKLIFDLLAEKKSISVWGCMTQLFFMHFFGGTEIFLLTMMAYDRYVAICKPLHYTSIMNQQVCAVLVGSAWIGGFVHSFSQILLILPLSFCGPNVIDHYFCDLLPVLKLACSDTFLIGLLIVVNGGTLSVISFVVLLASYLVILFHLRTQSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRPSDTLPVDKMIAVFYTVITPLLNPLIYSLRNAEVKKAMKNLWFRIMKADEK", "length": 309 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KB39-1", "protein_name": "Myb/SANT DNA binding domain containing 5 like 1", "gene_name": "Msantd5l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQREANQGESLENTEESNVGKSVKEEEQRPSGRSRSSWTDSEIRVFLQEWEVVEQEMGQPGRKLHKKTKSLCQRLYQQGLKKSWKSCFHLLLSLQDLHRTLCNERPGIEPLFSPYSEALYRILGSTPHESWFPGPLYDEADDSMLPVYPQPPMYQPSDYGITVPSAQLQGNPVPMMCQEDSPFPTWEPWNPSYPLSVPHLLPGFAPGDPSLQQPWSMCDLHQDPQ", "length": 225 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KBC9-1", "protein_name": "Leukocyte immunoglobulin-like receptor subfamily B member 3-like", "gene_name": "Lilrb3l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFTFTALLCLGLTLRLWIPVLTGSLPKPILRVQPDSVVSMGTKVTFVCEETIGVKESHLYRNGNLQRTVLKNHQKPTNKTEFSFSNVDQQMQQYQCSYRTQTKSSDYSEPLELVVTGAYSKPSLSAQTNPVVTSGGYVTLKCEPSQDNHTLILTVEGSQKHSWRKDPECNRYTEKCHALFYVGPLTSNQRWIFRCYSYEKHTPQVWSAPSEPVELLVSGKLQKTTIKAEPGSVIRSGRAMTIWCQGDLDAEIYFLHKEGSHNTQSTQTLQQPGNKAKFLIPSVTQRHAGQYRCYCYSSAGWSEPSDTLELVVTGIYYYGVKLSGLPSPVVPEGGNVTLHCTSHSNYDKFILTKEDQKFTSSLDAEYIPSTGQHQALFVMGPMTPNYSGTFRCYGYYKHTPQLWSVPSELLKIFISGPSRKPSLLSHQGHILEPGMSLTLQCYSDTKYDKFALYKEGGTDIIESFSQWTKAGLSMTNFTLSVMPNSTVHSGENVTLMCWSTYSVDTFILSKEGSGQPPLRLKSKIQDQQYQSEFSMSGVTSKLSGTYRCYGSHDSSLYLKALIGVSVAFLLFLFILIFILLRRRHQEKFRKDDEDAQKGKELQLSTGAAEPVTRDRGHQKRSNPAAATQEESLYASVEDMETKDGVELDTWKPPEGDPQGETYAQVEPSRLRRAGAISPVVSREQLNTKYEQAEEGQEVDSQATESEEPQDVTYAQLCSRTLRQGTAAPPLSQAGEAPEEPSVYAALATARPGAVPKNKKQ", "length": 761 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KIH5-1", "protein_name": "Major histocompatibility complex class I LLA precursor", "gene_name": "mhc1lla", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGKVLFVLFLLSAPTTVLTDSHSLWLLGTYIKGETQFPKLSFTVMLDDLRVGFYNSETKEFIPRDNTTNEDEAVSDVLTVIQNTLEPFMMSTLTFKNGTESPQLFQITWHCELLDNDKPGQIIFKIAFSGSTTDEVSFYNDNFTCQCQNNMATVPLESFQMHYETVCYPNCIATIRDYLKKRQTQVNGKVQPKVRLIKKVHPKSGGFRLSCLATEFYPHSINLTLLRDGQPVSDHEVTGGNLLPNGDGTYQMRKSLEIRADEREKHKYTCSVSHLSLDKILDIDFEFDPSFLIKIVIPVVVLLSLMLVLTAVLIHKCKNKRAESKETITTASTPEPTEMSETLRK", "length": 346 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IEQ0-1", "protein_name": "Guanine nucleotide-binding protein subunit alpha", "gene_name": "gna11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLESMMACCMSEEAKESKRINAEIDKQLRRDKRDARRELKLLLLGESGKSTFIKQMRIIHGTGYTDEDKRGYTKLVYQNIFTSMQAMIRATEHLKIPFRFEDNKKNALLVREVDVEKVCSFEQPYVAAINKLWMDPGIQEAYDRRREYQLSDSTKYYLNDLERISSRGYMPTQQDVLRVRVPTTGIIEYPFDLENIIFSYLSDLERISDPSYLPTQQDVLRVRIPTTGIIEYPFDLQSIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKILCSHLVDYFPEFDGPQNDAQSAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQHNLKEYNLV", "length": 400 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4ILG2-1", "protein_name": "FXYD domain-containing ion transport regulator", "gene_name": "fxyd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGVESPEHSDADFTYDYELIRRGGLIFAAVLFCLGMVIIFSKKLRCGKSSATHEDNGDL", "length": 59 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IU63-1", "protein_name": "Metabotropic glutamate receptor 5", "gene_name": "grm1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMLILRMNFFIVFLLFCTRLHLSTERSAVSRAASRSVARMDGDIIIGALFSVHHQPSAEKVAERKCGEIREQYGIQRVEAMFYTLDRINSDPYLLPNITLGCEIRDSCWHSSVALEQSIEFIRDSLISIRDEREGPKWCVEGNPSAQPPATKKPIAGVIGPGSSSVAIQVQNLLQLFNIPQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARALLDIVKRYNWTYVSAVHTEGNYGESGMEAFKELASQEGLCIAHSDKIYSNAGEKHFDRLLRKLRERLPKARVVVCFCEGMTVRGLLMAMRRLGVAGEFLLIGSDGWADRDEVVEGYEEEAVGGITVKLQTEEVTSFNDYFLKLRLATNNRNPWFAEFWQHRFQCRLAGHPQENTNYRKNCSGYESLEDNYVQDSKMGFVINAIYAMAHGLHDMHEHLCPGHVGLCEEMDPIDGSKLLDFLLKTSFAGVSGEDVWFDENGDSPGRYDIMNLQYVEPGVFDYINVGSWHEGILSIDDYMIQMNRSEMVRSVCSEPCSKGEIKVIRKGEVSCCWICTPCKDNEYVQDEFTCKACELGWWPDEELQVCEPLPLRYLEWSHPESIAAVVFSCLGILVTSFVTLVFILYRDTPVVKSSSRELCYIILAGIFLGYICPFTLIARPSIASCYLQRLLVGLSASMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVVIAFILISMQLTLEVTLIILEPPEPIKSYPSIREVFLICNTSNMGMVAPLGYNGLLILSCTYYAFKTRNVPANFNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTSFSVSLSVTVALGCMFTPKMYIIIAKPERNVRSAFTTSDVVRMHVGDGKIACRSNSLLNMFKRKKNASGNANSNGKSVSWSEPGSRHPPKGEHMWHRLSVHVKKQEAGSNQTAIIKPLTNTYNNPGMEFSDLSTKTLYNVAEEDEIDPIRYNPSNSPHLMAPVSKPMKEVGANLTFYTPEQHVPQQNSVLPQHAMIEHFQDDVVKYNSNMADLDEIISLPEPTDGIILALQPQVLHPHPILPMNVYQDEPSSPLEEVENEQFGLLHGYMYDNAQIHDEEELVQIKMAMEDSMALMPPSPFRDSLGSGSPVRNSPVSESVLCTPPSVTYASVILRDYKQSSSTL", "length": 1158 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4IUN8-1", "protein_name": "Trypsin inhibitor ClTI-1-like precursor", "gene_name": "spink2.9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLAQIVLLLCLSVMATAADKCPSVPNCSRYHPHACTMEYWPVCGSDGNTYGNECELCATIFEEKLNIILISKKGEC", "length": 76 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A0R4J2B9-1", "protein_name": "BTB domain containing 35, family member 23", "gene_name": "Btbd35f23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPVSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFTNILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQKCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICNLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNQEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A140T8Q5-1", "protein_name": "BTB domain containing 35, family member 21", "gene_name": "Btbd35f21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMILYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GQX3-1", "protein_name": "Cortexin domain containing 2", "gene_name": "Ctxnd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCVLMEDSSMSNGIDVDKGFAIAFVVLVFVFLIVMVFRCVKLVKNPYEVSSTTADLPLN", "length": 59 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GRH6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 3", "gene_name": "Zscan4-ps3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVRQFPHGARRASQGTPSHHVDIQSPPTTADVTMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGFPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCKSHQKRFCRDAKLYKCEECSRMFKHARSLSSHQKTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GS00-1", "protein_name": "Predicted gene, 36210", "gene_name": "Gm36210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHPGSPAAPGVSEPGPRELCAFVSGASAHMLRALQPRRIRPSKRRPNHRRFLHNQICREFAKIEAATQHLALTILSQKAPAQRPPFRRPPPPPPSPFLGVACAEAPMEAPHGSPSLSPVALDTSTLDLFDDILLTPTPRPLVTPDSFCQTLPAGNPQVASDVISHALGPGDQGQPTPIQAPRFSNLLLPPQKAQGGSLEPAALGCGWVDSWEAPYACDPQGVLDSWGAL", "length": 229 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSB3-1", "protein_name": "Family with sequence similarity 236, member D", "gene_name": "Fam236d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATEGVATAHTMLTSRGPRDTREPAPPTRSWRSRFQRALARVSKFFRRGRRTARG", "length": 72 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1B0GSI2-1", "protein_name": "Family with sequence similarity 236, member C", "gene_name": "Fam236c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVMHLVGHPQLTGTEGVATAHTKENSSRGPRETREPAPCTRSWRSRFQRAVARVSKFFRRRRRST", "length": 66 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYU6-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 2", "gene_name": "Zscan4-ps2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQYATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEGNVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSVPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1C7CYV3-1", "protein_name": "Zinc finger and SCAN domain containing 4, pseudogene 1", "gene_name": "Zscan4-ps1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWAIQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYTLTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNTSCNATEGNVGERCGGNEMDSLLIIQKEQHPEHEEGNVVCRFPHGARRASQGNSSHHVDFRSALTPADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSSDNIPRKKTDSLSINKRIYHPEPEVGDIPYGVPHDSTRASQGTSTCLQESLGECFSEKDPREVPGLESRQEEPISDPVLLGKNHEANLPCESHHKRFRRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCFTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1D5P3Y4-1", "protein_name": "Large ribosomal subunit protein uL24m", "gene_name": "MRPL24", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLSALLRLAAPPKLPKGYRHGTWRPGTAAERLRNPPGQRRKKIFVEPISREDWKVFRGDTVQVLTGKDAGKQGMVTQVVRARNWVVVEGLNTHYRYVNRDAKYSSTYIASEAPLLLNQISLVDPEDRKPTEVDWRYTEEGERVRVSLRTGRIIPLPLWQRRDGIVPEQWIDGPKDTSVDDALDKTYTPSLKTFEEEIMDAMGIVETRRAKKSYWY", "length": 216 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5PNZ8-1", "protein_name": "ODF3A protein", "gene_name": "LOC124417034", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPATKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A1D5RLF0-1", "protein_name": "F-box and WD-40 domain protein 27", "gene_name": "Fbxw27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METHLPSLPLMKIFSYLDAYSLLQVAQVNKNWNALASSDVLWRKLCQKRWLFCDMVTLQLQDKETWKQFFVYRTWQEHSKTRANPRDFTYKEIPLQYGPCGYACYISGCGITRKGQDKSVVCMVNSKNTISTWDVHKSVITWVSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNILESPCKSLKAVITKDDPIVLVSDILGNLYIFRIPDLHLISTVNVLPCDIDEIYCSPQKKWVLLSKKQPYILPKVFYMSSLLRTSEFSAPVSTLLEISLCQEAFWTPRREDRLTLMSRSGCSKITKFETYDMKLEEFGNKIIVKGNSIAGFLLPYYTESLNWFGVSDKDTIVCSTEFSLLLFTNNGHRLQTFQYFSETIVRLSVDPVHVIVTCNDGSLDVYAWEERSLLLRKCYRLKNRRHLSPRGFINKTLCDDVSIIQLMIDGHDTWFLMAYALNICS", "length": 466 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1P8ASP4-1", "protein_name": "Serine/threonine-protein kinase PRP4 homolog", "gene_name": "PRP4KB", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVSDKHVESNHRKHRRSFSPSDEVFKSPKRHKSRHHHRRHGHRHHRDEEVQYNDDENVNGGDLDMEEGEILGKEGIGETLKKKLESVDEFGDIKSGQFRENNLAFNGDDGFPLICKSWIRVYNYLSYKCHGRNQRRERECEKRKEIEPDRERRKERGSVDRDSRGDREKDYLRDRDNDRGRSRDKARYSSRERGRENERERRSEKDRDKGREFQSDREKHKSLDDGYGEVRHKHSGHSRHDAEDDLELRSPTSVNGHDPNSGDVKETRGNVERTRIDNDDKGDVVVWEVEQEDEELNLIEESRRRTQAIMEKYKKKLEQQNGFSSHDLELANIPKQSSTVADVLGSGTLGPVTSAVNQAKAGLDIDAVDGEVAKLSSAVGESPAQLVISDSDRTLASTGLGEGSPKDKISDDMFTDDIFGESPADSQKMVCTLTQIIDLVFIEFSNSGFICFVFPVHHLTRYSRNGLPFVHYIFVGYLRGKGNGIPIVRSGLDDNWDDAEGYYSYQLGELLDDRYEIMATHGKGVFSTVVRAKDTKAELGEPEEVAIKIIRNNETMHKAGQTEIQILKKLAGSDPENKRHCVRFLSTFKYRNHLCLVFESLHLNLREIVKKYGRNIGIQLSGVRVYATQLFISLKHLKNCGVLHCDIKPDNMLVNEGRNTLKLCDFGSAMFAGTNEVTPYLVSRFYRAPEIILGLPYDHPLDIWSVGCCLYELFSGKIMFPGSTNNEMLRLHMELKGAFPKKMLRKGAFIDQHFDKDLCFYATEEDSVTRKTTKRMMVNIKPKEFGSVIKQRYKDEDSKLLVHFRDLLDRIFILDPQKRITVSQALAHPFITGK", "length": 834 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1P8BFV1-1", "protein_name": "Bax inhibitor-1 family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGLKDFSRISPAIQSHLMRVYFSLFCILAASAFGAYLHMRLNIGGTITKLGWVLSLLEHVVSCPPYKHKIRFSLLLLFGVLHGASVGPCIKSTIDIDSSILITAFLGTAVIFFCFSAVAMLARRREYIYLGGLLSSGFSLLTWLKNSDQFASATVEIQMYLGLLLFVGCIVVNTQEIIEKAHCGDMDYAVHSLILYIGFVRVFLQILSIMWNTSADRIRRNNEET", "length": 226 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "A0A1W2P6Q8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7S8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDKTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKMRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLIGGLNTPLHESDFSGVTPQQQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLHINPEDGMADHSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQATRDAERVKEMKRMHKAVQKDLPRPSEVNETILRPFDVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGFATNDSEHITYLEHSPYEKFSKEDLKKAQDALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLYLPAQSCYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKHEDSAIPRRLECLEEDVQRQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P7Z8-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAVMKYGKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPFRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2P855-1", "protein_name": "Cell division cycle 5-like protein", "gene_name": "Cdc5lrt8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRIMIKGGVWRNTEDEILKAAIMKYRKNQWSRIASLLHRKSAKQCKARWYEWLDPSIKKTEWSREEEEKLLHLAKLMPTQWRTIAPIIGRTAAQCLEHYEFLLDRTAQRDNEEETTDDPRKLKPGEIDPNPETKPARPDPIDMDEDELEMLSEARARLANTQGKKAKRKAREKQLEEARRLAALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLRQQDLDGELRSEKEGRDRKTDKQRLKRKKESDLPSAILQTSGVSELTKKRSKLVLPAPQISDAELQEVVKVGQASEVARQTAEESGITNSASSTLLSEYNVTNNSIALRTPRTPAPQDRILQEAQNLMALTNVDTPLKGGLNTPLHESDFSGVTPQRQVVQTPNTVLSTPLRTPSNGAEGLTPRSGTTPKPVTNATPGRTPLRDKLNINPEDGMADYSDPSYVKQMERESREHLRLGFLGLPAPKNDFEIVLPENAEKELEEREIDDTYIEDAADVDARKQAIRDAERVKEVKRMHKAVQKDLPRPSEVNETILRPFNVEPPLTDLQKSEELIKKEMITMLHYDLLHHPYEPSGNKKGKNVGLATNDSEHITYLEHSPYEKFSKEDLKKAQGALVQEMEVVKQGMSHGELSSEAYNQVWEECYSQVLSLIAQSRYTRANLASKKDRIESLEKRLEINRGHMTTEAKRAAKMEKKMKILLGGYQSRAMGLMKQLNDLWDQIEQAHLELRTFEELKKREDSAIPRRLECLKEDVQLQQEREKELQQRYADLLMEKETLQAKF", "length": 802 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1W2PP81-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 5", "gene_name": "TAF11L5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A1Y7VLT7-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A1Y7VNG9-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRHRGKNENESEKRELVFKEYGQEYAQVTKMLGCLWLEAMCFDGVKRLCHIRGKLRKKVWISTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINETDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YCH8-1", "protein_name": "Predicted gene, 47985", "gene_name": "Gm47985", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGAPHNSAKRHRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPIVLQRAWLTWQLSHAGAALHWALHTVKSILTSQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YD13-1", "protein_name": "Predicted gene 8947", "gene_name": "Gm8947", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKREQLLDKKAEDKQPPESRCNNGRSSKSSPMGKENTWPSREAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDQRSQPRSPVRTLKRSRSGDRQGAPHNYAKRRRQTFPPEASCSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYIWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 301 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YE43-1", "protein_name": "Predicted gene, 47996", "gene_name": "Gm47996", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALGAELSETLVEKPEHMNLEMSILAPSKRKQLLDKKAEDKQPPESRGNNGRSSKSSPMGKDNTWPSPEAKVPSQKRSGQSWAVSSCGPHKRSSKLEDKRRNRPSRFRERGRDKPGSTHKRDSSHTKLHVKDRRSQPRSPVRTLKRSRSGDRQGVPHNSAKRCRQTSPPEASSLPTFSLLMSRVFTNVDALQVSLDDLQAPGGAFLRVPSSSTEPSVSQRAWLTWQLSHAGAALHWALHTVNSILTAQASLPRYTWPQGYSFTADPRPVPTSKIQASQLAQRPGDLASPNPSVDTRSILG", "length": 300 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286ZIN6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258935", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANLTSMSGFLLMGFSDDHKLQILHALLFLVIYLLALTGHLLIITITTLDHHLHSPMYYFLKHLSLLDLCFISVTVPQSIANSLMNNGYISLGQCILQVFFFIALASSEVAILTVMSYDRYVATCQPLQYETIMDPWACRQAVIAVWVTGGLSGLTHTAINLSVPLCGDRVIHQFFCDVPQMLKLACSYEFINEIAVAAFTTSTAFFCLISILLSYTRIFSAVLRIPSAQGRTKVFSTCLPHLLVVTFFLSAAGFEFLRPPSDSQSAMDFMFSIFYTVVPLTLNPVIYSLRNKAMKAALRKVLSKEEFAQRKKYFKALFQL", "length": 321 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZIP8-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259124", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "QEYKANGGDNTTTIIHFVLLGFSDFPHIRPALFVVFLVIYILTLTWNLCLIVLIRLDSHLHTPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECCLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVQVLTAIFTVFFGIINALVIMMSYVYIVISVMKITSAKGRSKAFNTCASHLTAVTLFYTSGIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 316 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZLI4-1", "protein_name": "C-C motif chemokine ligand 24", "gene_name": "CCL24", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSPSSLIKASGQLQCPAGNRLLAPTLSSCIAALSPELPLLLSRHGRPVTVAASLLFLGLCAYSFAPADSVTMPSSCCIYFISKKIPESRVASYQLSNSSVCPQAGVIFTTRKGQKFCGDPKQLWVQKYMKKLDAKRKKASTRIRAMGTGAPVRRGPANSTSI", "length": 163 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZSE3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258059", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPKLQVLIFIFLFVAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEISFISSCIPRYLYSIATGDKVITYNACVIQVCFTDLCGVTEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSVQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZU87-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100152920", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILETMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDHYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSTVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSWRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZVC9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258401", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZWC4-1", "protein_name": "Zinc finger protein 16", "gene_name": "ZNF16", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLPLSQVPAMPSLRTRPGKAEMEPSVPGPSLRTPGTQVSVSDAPAVTHPGSALHGPLSCGDTEPGATPPHHQLADWDLRTEGSQLLQKEDASEDLESQAGTSEDYVGAGSQAPERGELCADVLGSDWGVPQGERLSLCQEGGFMPAYLLPGSPLEEPEIDTEPLERNFGLIITPVASPGEPEEETPQPFDACDQSVHCGVDLAGHEGLHAAESSFICGECGESVGLHSDLLRHRLSHRGEKPHVCAECGEAFSQSASLESHQRSHEPAKPFQCSTCGKAFGRSSSLIKHHKVHTRERPHACGECGRPFSRFSNLVKHRRVHTGEKPYRCSECGKAFSQSSSLLQHRRVHTGEKPHVCPVCGKAFSYSSVLRKHQIIHTGVKPYSCSACGKAFSHSSALIQHQGVHSGDKPYECRECGKTFGRSSNLILHQRVHTGEKPYECAECGKTFSQSSTLIQHQRIHNGLKPHECDQCGKAFNRSSNLIHHQKVHTGEKPYTCVECGKGFSQSSHLIQHQIIHTGERPYKCGECGKAFSQRSVLTQHQRVHTGEKPYDCEACGKAFSQRSKLVKHQLIHARE", "length": 576 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZX75-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100156955", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "IFIMEWENQTASSDFILMGIFSHTPTHIFLFSLVLGIFTVALLANTVMVLLICLDRRLHTPMYFLLSQLSLMDLMLICTTVPKMARNYLSGRKSISVAGCETQIFFSVSLFGAECFLLAVMAYDRYAAICYPLQYPQLMNWNVCGLLAASSWILGVFDGIVDIAATLSFSYCGSREIPQFFCDITALLRLSCTDTSTFETLVFICCVVMLLFPLSLIIISYTRVIITVIRMSSGEGRHKAFTTCSSHLVVVGMYYGAAMFIYMRPTSNRSPAQDKMVSAFYTILTPMLNPLIYSLRNKDVAKAFSRCWGREI", "length": 312 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZY56-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258501", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METDNDTQILEFLLLGFSKQPESQPIIFGLFCSMYLITVFGNLLIILAVISDYHLHIPMYFFLSKLSFVDICFTSTTIPKMLWNIQTQSKAITYEGCITQIYFLILFAVLDILLLTVMAYDRFVAICHPLHYTVIMNPRLCGLLVLVPWIMSVLNSLLQTLMMMQLSFCTNFEIPHFFCELNQMIQLACSDTFLNTIVMYFAAALLCGGPFFGILCSYSKIVSSIYRISSAQGKYKAFSTCASHLSVVSLFYCTMLGVYLSSAAAHSSHSSATASVMYTVITPMLNPFIYSLRNKDMKRALKALFVKGPM", "length": 310 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A286ZZP6-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MANAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHLPNYH", "length": 402 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7E2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258743", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNSTSLHDFILLGFSDHPKLEMALSGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFPDLCFTTSIVPQMLVNLWGPHKTISYGGCVIQLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKVACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSRAGQRKAINTCGSHLTVVSIFYGAIIYMYLQPGNNASRGQVIFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 320 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A7J9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258750", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVKEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLAFVDLCYATAITPKVLQNLMSTEKSISFIGCMVQLFVYGTFVTSDGYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSCFMGFLNACVNGSLTFQLNFCKSNKINHFFCDAPPILALSCSSIYFNIMLLAAFVGFNLMFTVSIIIFSYIFILAAILKISSAAGRKKAFSTCGSHLTAVTIFHGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMLNPLIYSLRNQDVREALKEIGKKML", "length": 309 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287A951-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "LOC100514137", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVHMNVLTDALESINNSEKRGKRQVLTRLCFKVIVRFLTVMMKHGTPIGKFEIMDDPRARKIVVNLTGRLNKCGVISPRFDGQLKDLEKWQNKLLPSCQFGFIVLTTSAGIMHHEEAR", "length": 118 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ACV2-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDAPTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLIKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEDSAWNKLQFYHNPNFKRGCPNLLVRMKRRVRVKNASPVSASLLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSTSTNLNVPLIRWPSMSQRISNTTTPTRSGLSSPSSPSVRPPGQIVMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYHRISNFPSGYFGLRVEPSPLPTRYQNISPTEGPVSNPQPAAHPWFPMPMATDTSVASLSRPNPQSSSISEHHPNYY", "length": 402 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AEV7-1", "protein_name": "Uncharacterized protein", "gene_name": "WFDC10AL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKWWGLQWLMLSCLAILPASGNWQERISASLEALTQSKLIPGMKPCKTIPTKEQCTYFCDLPRACPTGLLCCSASCGNVCMPPKGHGNRRSSHKISNFLFTAEPIKQQ", "length": 108 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AF12-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTNTKGKRRGTRSMSSSPFRKHGVVPLATYMRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRVYNVTQHAVGTVVNKQVKGTILAKRINVHIVHIKHSKRGDNFLKRVKENDQKKKEAKEKVTWVQLKHQTAPAREAHFVRTNGKEPELLEPNP", "length": 155 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AGK9-1", "protein_name": "DM domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPDEMPTVPCCPLDSTTGLETGAPWGIEFGPRRAIRRCARCHNHGITDQIKDQEHLCLFQACECHKCVLFSEHCSILPAESALKTMQELHLKRQLTQGLIKSGTTSPKAHSHVKKSSIQTGVLSKLPRCSADRSGIGIFVSVLDSSTLEEATNNFTFQEVTQAPCPAQQAPKTSDQDSDSASLEWQRKLEAAEALLTLRESSQAPSGPTPLLQPSAAPAPAGERGLQPPSRSLRPRPASSISLPIGHVGCISLLS", "length": 256 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AKK8-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100155397", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDVRNHSIVSEFVFLGFTNSWEIQLLLFVFSFLFYSSSMMGNLVIVFTVTLDSHLHSPMYFLLANLPAIDMVFCSITAPKMIGNIFKKHKAISFCGCITQIFFTHAAGGTEMVLLIAMAFDRYVAKCRPHHYLTIINPRICLCFLVTSWIIGLIHSMAQLFFVVDLPFCDLNVLDSFYCDLPRLLRLACTDTQELQFMVTVNSGLLSMGSFVLLIISYIFILFTIWKHASGGSSKALSTLSAHITMVVLYFGPLIFFYTWPSPTSHLDKYLAIFDAFITPFLNPVIYTLRNKEMKVAMRRLFSHLVHYRNIS", "length": 312 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AP00-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258730", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "SRHDLHCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLTGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCDHLAMVSWGVGCMAALGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSMPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTVVTSMLNPIIYSLRNKDVKAALRRTLGKKKVLAHR", "length": 322 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287ARD5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258934", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLTFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLFYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AT12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLSFNRTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQFFIIHCIFMSESGILLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIFLRSYCTVFPIIFLLKRLTFCRNNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDILLIFVSYMLILRAVFHMPSQDARHKALSTCGSHVCIIILFYGPGILTTLAQRFGRHIPAHIHILLANVCVLAPPMLNPIIYGIKTKQIQEQVAHLFLKQK", "length": 313 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AUC4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MERINKSHPEEFILLGFADRPWLELPLFIILPMYFFLTNLSFLDMCYTTSIVPQMLFHLGGSEKTISYLGCAVQLYFFHTMGGTECLLLALMSFDHYVAICKPLHYTLIMNRCTCILLVATVWLSGMTYAVSEATVTLHLPLCGHNTLDHLICEIPVLIKAPCGEKGTNELTLSVVCIFMLAVPLCFILASYASIGHAVFKIKSSEGRKKAFGTCSSHLIVVFFFYGPDISMYLQPPSSISRDLPKFMALFHGVVTPTLNPFIYTLRNKDVKGAWGNLVRSVFTSK", "length": 286 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AXC2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTEVNEFILLGFAGQHKSWLVLFIVFLGIYVVTLVGNIGMILLIKIEMLQNFVGTEQSISFIGCMVQLLIYGAFVTSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLLIGSYLIGFLNASVHVSFILPLNFCKSNKINHFFCDAPPILALSCSSIYFNVMLLAAFVGFNLTCTVLVVIFSYIFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 281 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287AY25-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100155405", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLSNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSRRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDRFFCNLPLVIELACMDTYKVEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRLSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNHHVNSWKY", "length": 311 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B1Z6-1", "protein_name": "Short stature homeobox", "gene_name": "SHOX", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEELTAFVSKSFDQKSKESSGGGGGGGGKKDSITYREVLESGLARSRELGGSDSNLQDITEGSGHCPVHLFKDHVDNDKDKLKEFGTGRAAEGIYDCKDKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTASHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL", "length": 292 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287B9C9-1", "protein_name": "HSF-type DNA-binding domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHAPSEIQGVSPKDESTGSESSITSPWCDNSITGDLDLRSQIEEKAFQALSEGSLMKEPCHTLCASEPDGDNDFPPLPFPRKLWEIVESDRFKSIWWDENGTSIVINEERFKKEVLERKAPFRIFETESMKSLVRQLNLYGFTKLRRNFQRPASLANILAEDNEVSAWNKLQFYHNPNFKRGCPHLLVRMKRRVRVKNASPVSASVLQGCSKKRSRTGGDVDNHNSDVAAETRGEDAFSASTNLNVPLIRWRSMSQRISNTTTPTRSGLSSPSSPSFRPPGQIAMAQHAIFSQLTTFHMHSQSSYSPASGHIVNFITTTTSISQYRCISYFPSGYFGLRVEPSPLPTRYQNISPTECPVSNPQPAAHPWFPMPMATDTSAASLSRPNPQSSSVSEHHPNYH", "length": 402 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BB76-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100157512", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAHTNESVVLEFVLLGLTNSWELQLFLFAIFSIVYVTSVLGNTMIIVIIASDSRLNSPMYFLLGNLSFIDICQSNFATPKMLVDFLVEHKTISFEGCMAQIFLLHSFVGSEMMLLVAMAYDRFIAICKPLHYSTIMSHRLCIIFVFISWAVGILHSVSHLAFTVDLPFCGPNEVDSFFCDLPLVIELACMDTYKIEILTLTNSGLISLGCFLALIISYTVILITVHRWSSSGSSKALSTLTAHITVVILFFGPCIYFYIWPFSRHSVDKFLSVFYTVCTPLLNPIIYSLRNEDVQSAMHKWRNRHVNSWKY", "length": 311 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BC21-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152520", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDGKNQTALSEFIILGFSNLNQLQFLLFTIFFLTYICTLGGNTFIILVTVVDPRLHTPMYHFLGNLAFLDICYTTTNVPQMMAHLLSEKKSISYGGCMAQLFAFIFFVGSECLLLAAMAYDRYVAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSAIFTYVRPISSYSLEKDRLISVLYSVVTPMLNPIIYTLRNKDIKEAMKAVGRKWQLPLLSFDV", "length": 317 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BF45-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100513333", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNRTITTFILLGLTDDPELQVLIFIFLFLAYMLSLTGNLTIITLTFVDSHLKTPMYFFLKNFSFLEVSFISSCIPRYLYSIATGDKIITYNACFIQVCFTDLCGITEFFLLAAMSYDRYVAICKPLHYVTIMSSRVCGILISSCWMAGLCVLIPPLSLGLNLKFCDSNRLDHFGCDAFPLVKISCSDTWPMEQTVIICAVLTLNMTLTCVVLSYAYIIKTIFRFPSDQQRKKAFSTCSSHMIVVSITYGTCIFIYMNPTAKGEVTIKKVVSLLIFSVSPTLNPFIYTLRNNQVKRAFKDSIKRIALLSTR", "length": 311 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BGE2-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENNQSWIAEFILVGFQLSEEMELFFFIIFFLLYIFNLLANGMILGLICLDPRLHSPMYYFLTHLAVTDISYASSNLPNMLENLVKHKKTIPFVSCTLQMLFYLAFASVECLILVVMSYDRYVAICHPLQYTVIMNWKLCTVLAIISWACGFFLALVQVSLFLRLPFCGPQKVNHFFCEIRSVLKVTCGETWINKIFLFADGVFILVTPISLMLVSYVRILWAILKIQSKEGRKKAFSTCSSHLCVVGFYFGIAMMVYLVPDDSHQQEEQQKILFLFYTFFNPLLNPLVYSLRNAQVKAAFHRIFQKNRTM", "length": 311 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BIM6-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGKRSRRKSPGRQGRTCARTTRAGLSASVSHMERLLREGPYAQCLSSSARVFLAATIEYLTARVLELAGDEAQIVGRRCITPELVAMAVHNNALLSAFFGTLAISQVAPTQE", "length": 113 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BK27-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVTEFIFLGLSNSQELQTFLFVFFLVFYVGIVFGNLLIVLTVMIADFFRKCKVISFKGCLAQIFLLHFFGGSELVILIAMAFDRYVAICKPLRYTTIMSSNVCVGIVAAAWGTGFLHSVSQLAFAVNLTFCGPNEVDSFYCDLPRVIKLSCTDTYRLDIMVIANSGVLTVCSFVLLIISYTVILVTIQHLPSQKSSKALSTLTAHITVVLLFFGPCIFIYAWPFPIKSLDKFLAVFYSVVTPLLNPIIYTLRNKDMKTAMKRLRKWNMNSRIKP", "length": 274 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKA6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259008", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTFNCSLWQDNSMSVKRFAFARFSEVTEQCFLLFTLILLMFLASLMGNALIATAIWTNPVLHTPMYFFLANLSLLEIGYTCSVIPKMLQSLVSEARGISREGCATQMFFFAFFGISECCLLAAMAFDRYMAICSPLHYATRMSRGVCVHLAMVSWGVGCMVGLGQTNYIFSLDFCGPCEIDHFFCDLPPILALACGDTSHNEAAVFVAATLCISSPFLLIIASYGRILAAVLSIPSPEGRRKALSTCSSHLLVVTLFYGSASVTYLRPKASHSPGIDKLLALSYTMVTSMLNPIIYSLRNKEVKVALRRTVGKKKVLAHR", "length": 320 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BKW4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258932", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEGENQTVLFEFIILGFSNLKELQFLLFTIFLVTYICTLGGNSFIILVTMTNLHLHTPMYFFLENLAFLDICYTTTNVPQMMAHLLSEKKSISYLGCMAQLFAFIFFVGSESLLLAAMAYDRYIAICKPLRYSVIMNKVLYSQLAASCWSGGFLNSAVHTVLAFRLPFCGNNQINYFFCDIPPLLVLSCGDTSVNELALLSIGVVIGWTPFLCIVLSYLYIISTILRIRSSKGRQKAFSTCASHLTIVLLYYGSTIFTYGRPISTYSLEKDRLISVLYSIVTPMLNPIIYSLRNKDIQEAMQVMGRKWKASSSLSFDV", "length": 318 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BLZ6-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC110258167", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGGKNSTTITKFILLGFSEFPKLTAVLFSVFLRISLMTVSWNMGLIMLIRMDSHLHTPMYFFLSNLSLLDICYVSTIAPRMLSDFFKKYKFISFMGCTMQYFFSSLALTECCLLAAMAYDHYAAICNPLLYTAIMSPTLCVQMVAGSCVTGFFGSFIQLCALFQLHFCGQNVTNHFFCDLPQLLILSCSDTFFFQVMTSVLTVIFGLTSVLVIIISYGYIIATILKITSSEGRSKAFNTRASHLTAVTLFFGSGIFIYMYPNSGDSLSQNKLVSVLYTVIISMLDPLIYSLRNKEIQDSLSRWRKTIFSWCY", "length": 313 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BNL4-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "TVLNARNVSTPKVFILLGFSDHPWLEMPLFIIVLAAYIRTLVGNISIIVVSRVDPNLDSPMYFFLSNLSFLDLCFTTTTIPQLLLNLWGPDKSISYGGCVTQFYMFHFWGATECIFLAVMSMDLQAICKPLRYPVIMHQQLCIFLVVMAWLSGLVNSLLQSSLTIQLPLCGNNKVDDFLCEVPVMIKMSCTDTTFNVAMLSIVGTFYSLVPLSLILVSYGFIVATVLRIQSSEGKKKAFNTCSSHTIAVSLFYGPVISMYVQPSAANSQDKNKLMSLFYSLVTPMLNPFIYTLRNKDMKGAMMRLLVSLYHQRRG", "length": 315 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A287BSD4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100525471", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENENSTVVAEFIFVGLTQSRNIQLLVFVLILIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNLRACYALLVALWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLMTLLCFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPAIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKRLLNQQLA", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A2R8VHJ9-1", "protein_name": "Predicted gene, 36245", "gene_name": "Gm36245", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTKNEEQNEDQSEGVVIPHIQDHHCLAILAFCFFFPLGYLAYRSSCKTRTYIEQKEYEKAKATSRCTFAFVLSSIAGGSIIFFCLFSRLFFM", "length": 93 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3L7ICH5-1", "protein_name": "Cytochrome c oxidase subunit 7A2-like, mitochondrial", "gene_name": "LOC100756118", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYYKFSGFTHKLAGAWALESYSPQGLKPVASTEAPPIVFATPTKLTSSVTAYVYAGKNKVPELQKFFQNFFHLKRGLPDQMLYRTPMALTVGGTIYCLSALYMASQTPNK", "length": 110 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A3Q1LL21-1", "protein_name": "BTB domain-containing protein", "gene_name": "LOC112445444", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGPLNSRNLQCRESGTGELQQPEAQAGPSYVSGSRKRKQSTGPSLGPESEMSHNQEEDLQQVVCTRQGKKVKIKSEYAYQTLFLNGETSDIKIRALGKVWCLHKRFLCQSDYFATMFRDSGKECHKDIIDLEINDQNINVESLQFVLGSLYRNEYVLIKPLQVPRVLATACLLQVEDLIQQCDKTMKETINVKTVCSFYVAAETYGLHSVKTGCFEWLLHNLMTHPSVELYKKLSTDLMNLVISSSNLFVMQKEIDIYTTLKQWMFLRLNPGWKGTMKQLLVNANNWFSRHKEHDGSISFLETKQGIVFQPVFKNLRFQHIICDLASTKVIEQDALIPSEWLSCVYKRQWYTLLRAQQYREIGPRDITETELEEYSMRCGKRIVRDGTYAWKWSGYNFGVHLYVVFTSHFIIFKRHAFSQPYDGSICLQPQRNIAFRLTLVYFGSSGKLSFRKTTGYKILTFEKDEEQMVMKLDSVALSFPLYIFCNFLFISLENPGN", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LLV6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIIIGTLITGYMVTCTCFLHYSCDSEEAHKATKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1LUU6-1", "protein_name": "Guanylyl cyclase domain containing 1", "gene_name": "GUCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTGPRCRRKQRPSGRPGPRGTRAPQHPTPDAGWTARRAAGAAGAEARGRDLPPQRKPAKPTAPGKGRPERGECPRRADRGGGDPEERAGGRPAWGPGAGRGGAWGRSRLPPLLPPGRWCWRPGKPARAGRALSSPVDARAAAGAGPGPWEPRAARVMRTEVDAEAAGPPLEPDEPTQSLSIQDQETAFLLEDSCQLKPGQPLPGRPWPSGDFVQLPVPIIQQLYHWDCGLACSRMVLRYLGQLDDAEFEQALQELRLTRSIWTIDLAYLMRRFGVRHRFCTQTLGVDKGYRSQSFYRKHFDTEETRVNQLFAQAKTCKVLVEKCRVSVQDIQAHLAQGHVAIVLVNSGVLRCDLCSSPPKYCCFTPSGPRCFCRSPDYQGHFIVLRGYSRAAGCVFYNNPAYADRMCSASISNFEEARTSYGTDEDILFVYADS", "length": 434 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1M0W3-1", "protein_name": "IF rod domain-containing protein", "gene_name": "LOC787600", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTCGSACFSSRSGVRSSSSCVTTQRYAPGRTFSCVSACGPRPSRCCITAAPYRGVSCYRGLTGGFSSRSVCGGSRAGSSSRSFGYRSGGPSPPCITSVSVNQSLLKPLNLEIDPNAQRIKHQEKEQIKSLNSKFAAFIDKVCFLEQQNKLLETKWKFYQNQRCCESNLEPLFNGYIETLRREAERVEADTGRLASELNSLQEVLQGYKKKYEEEVALKTTAENEFVKIKQEVNRAYVLKGDLEANAHSLVEEVGFLKTLYEEELRVMQAHISDTSVVVKMDNSRYLNMDSIVAEIKAHYDEIASRSRAEAESWYRSKYEEIKATVIRHGETLRRTKEEINELNRLIQRLTAEIENAKSQNSKLEAAVTQAEQQGEAALNDARGKLAGLEKTLQKAKQDMACLLKEYQEVMSAKLGLDIEIATYRRLLEGEEQRLCEGISAVNVRVSSSRGGVVCGDLSATRTCGIGSYGVGACGSSCKKC", "length": 480 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MFB0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112441459", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELWRRLLIIVIGTLITGYMVTCTCLLHYSCDSEEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKSTWPPSLQCRVKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVTLFSRELKHFYKSYKKKQPIYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDMFKNSQNN", "length": 361 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MI36-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGSSSGSKAEFIVGGKYKLVRKIRSGSFGDMYLAINITNGEEVAVKLESQKARHPQLLYESKLCKILQGEVGIPHIRWYGQQKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQMMGRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKNLTGTARYASISAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKKMSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRHLFHILFRTLNHQYDYTSDWTMLKQKAAQQAASSSGQGQQAQTPTGF", "length": 325 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MQ28-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "KEQVLQPTTVVSLEGAVAEISCNHSVSDVYDFFWYLHFPGFAPRLLIKGLGPSQQGRYNMTYERFSSSLLILQVQTADAGVYYCALRYTEAGHP", "length": 94 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MT47-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC112444909", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLGCEGGKRPLKPPKKQAKETDEEGKAFKHKQKEEQKTLEGLKGQIMGKVPLATGGIKESGKQ", "length": 63 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q1MUP8-1", "protein_name": "E3 ubiquitin-protein ligase", "gene_name": "LOC100336539", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSRLTERALPTGTSNGAPSSRRAPVLTGTTVSNNDLASLFECPVCFEYVLPPITQCKSGHLVCGNCRPKLTRCPTCRVPLTSIRNLAMEKVANLVLFPCKYTSSGCGKTMPPTEKADHEEHCEFRPCRCPCPGTSCGWQGSMDAVVPHLMQHYNESIITLRGEVVVFLAVNINLAGTLEWVMLQSCFGFHFLLVLEKLEIYDGHQKFFAVVQLIGTREQAENFTYQLELNGNRRRLSWEATPLSIHEGIATALINSDCLIFDSEVAELFAENGNLSIDVTISMC", "length": 284 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A3Q2TUK0-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC121109925", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDEKGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A3Q2UEY0-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418381", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSSYTIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A494C0N9-1", "protein_name": "Protein FAM246B", "gene_name": "FAM246B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPGRPWAQARSAYRASEVLRRVTGRRRDPGPQSNGPGREDARAPGRLARLLRQLRAEAASRSEVPRLLKLVERAGAGAAGAGERTGAHSRGSVCSVCGEPRGRATYPAGVLEVSERRLQEGLAAVREELGAEIEALRAELRAELDALRALLPPPPPSPPARREPRAVPRAAPRGPTLLRTLGTVSALVAASRPADDAPDGPAECGAHRAPARKNHKKMPVPPGAPQGGGD", "length": 232 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A494C0Z2-1", "protein_name": "Speedy protein E13", "gene_name": "SPDYE13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A4X1TRA8-1", "protein_name": "Small ribosomal subunit protein eS19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGVTVKDVNQQEVVRALAAFLRKSGKLKVPEWVDTVKLVKHKELAPYDENWFYTRAASTPRHLYLWGIAGVGSMTKTYRGHQRDRVMPSHFSRGSKSVAHRLLQAREGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAAKKKH", "length": 145 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1TY10-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100627324", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MENYNQTSIYFILLGLFPSSRIGMFLFIIIVLIFLIALFGNFSMILLIFLDNNLHTPMYFLLSQLSLMDLTYISTIVPKMAYNFLFNDKSISFIGCGIQSFFFLTLAGAEGLLLAAMAYDRFVAICFPLHYHIRVSKRICVLMIIGSWIMGSINSFAHTAYALNIPYCQSRAINHFFCDVPAMLTLACIDTWVYESTVFVSTTIFLLVPFTCIAFSYGRILLVVHHMNSTEGKKKAYSTCSTHLTVITLYSAPFAYTYLRPKFLRTPTEDKVLAMLYTIFTPMLNPIIYSLRNKEVMGALRRVIQRICSVKM", "length": 312 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1U699-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSVSMSKFVLVGLHIWPEQQGMVFALFLGMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLAFSDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFFSCIDNLLLAVMAYDRYVAICHPLRYAIIMKEELCLCLLAGSWLLSCAYALTHTLLLAQLSFCADNIIPHFFCDLASLIKLSCSDTSLNELVIFSLGPAVFIFPLSGILVSYGCIVVSILSVHSPKGIFKALSTCGSHLSVVSLFYGTSMAVYLSSSSGQSHDKDTIASIMYTVVTPLLNPFIYSLRNRDMTLALQILFRNSNLLAK", "length": 315 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A4X1VK25-1", "protein_name": "Elongin-C", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RSYGGCEGPDASYGKLIASDKFIVKREHVLTSGAIKAMFSSPGQFAEKETDVVNFRETPSGIPSAALWKVCMYLPHKVCYTSNTSEIPEFPINSEFPIAPDIALEPLMAANLLDC", "length": 115 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A571BD55-1", "protein_name": "BTB domain containing 35, family member 26", "gene_name": "Btbd35f26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BF50-1", "protein_name": "WD repeat domain 88", "gene_name": "Wdr88", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDNEEILNSPDQVRKGSPDVKKKKKIKKKRVKPKGDLDSKKLDFVEDSWWKGSLKNKNLDFAEYNWVLVDNRRVSVDSRKSSADSKRGSADSKRGSADSKRGSADSKRGSADSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKRGSVDSKNRFSPKKMDFSEDREISQPTFLRAQQSKVPWALMRALGLFKLSLPDIRRYYNLTSHDPLALDKDRQPREKSHMATVKKFWGNQQPLSKIPYKILIGHDHIVSSCHFCMNDTRFLSSSYDCSVKLWDAEDGTVIWDFEPRPKAPVLECSITADNRRIVASSYDKTVRAWDVETGQLLWKVRHDTFVVCCKFSPNGKFVLSALDVDRGIYLMDPENITTVIHMKDHHQRSITSCCFDPDSQKVASVSMDRCIKIWDITSRTTLFTIPKAHYNAISDCCFTSTGHFLCTSSWDKNIKIWNVHTGEFRNRGACVTLMKGHEGCVSSCCIARDSSFLISGGFDKTVAIWDVGGGYRKLALKGHEDWVTDVAISNNKKWILSASKDSSMRLWNIEEIDKIPLVSENKKAMGLKVRQVGIR", "length": 565 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG45-1", "protein_name": "BTB domain containing 35, family member 25", "gene_name": "Btbd35f25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGLQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A571BG86-1", "protein_name": "BTB domain containing 35, family member 8", "gene_name": "Btbd35f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESRHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A5G2QG78-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100523228", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTRGENTTNITDFVLLGFSDFPQIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHTPMYFFLRNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYFVCSTMGLSECGLMTVMAYDRYAAICNPLLYSSTMSPSLCGRMVLGSYMAGLSASLSQVCAMLQLHFCGPNVIHHFFCDMPQLLVLSCSDTFFLQLLTLVLTVIFGILNALVIMMSYVYIVISVMKITSTKGWSKAFNTCASHLTAVTLFYTSIIFVYLSSSSGGSSGLDRFAAVFYTVVIPMLNPLIYSLRNKDIKDAWKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QIN7-1", "protein_name": "ADAM metallopeptidase domain 7", "gene_name": "ADAM7", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSNSHYLSALFSREFLASNYSETYYSTKGEEVTTHPQIMDHCFYQGSIIHEFDSAASISTCSGLRGFFRVNDQRYLIEPVKYSDEGEHLVFRYNPKVQHAANYSCTELNFTRTAVLKDNTKSMEDSKMESIEKEKHIELFIVADNNVYHRNPNSKVRNRVWGMVNFVNMIYKTLDIHVTLVGLETWTNGDKIEIDSNIETTLKRFSAWQEIILKKKKNFDHVVLLSGKWLYTSAQGTSYPGGMCLPYYSSSVVKDLLPDLNTIASRMAHQLGHSLGMKHDDYPCTCTLGKCVMDSGGSIPALKFSKCSRTQYQQYLKDFKPTCMFDIPFSDKLSDYPYCGNKKLDDGEECDCGPVQECTNPCCDARKCMLKPEFTCAEGECCESCQVKKAGSLCRPAKDECDFPETCTGHSPACPKDQFQVNGFPCKDAKGYCFMGNCPTRDDQCSELFDNEAKDSSDICYKMNKNGNKFGYCKNEEQTLIPCEEKDVKCGKIFCTGGKHASILGEEKVYHLKKPLTQNVTECKTFFLYHKSKDFGLVAPGTKCGEGKVCSNSECVTIEKAYNSTDCPSPCNENAVEDGDLGCQCEGVQASVDWEETLNVTNISILVVVLILVIIGVLSAVLLIRYQKCIKLKQVQRPPSEALGVENKGYTGDEQQTRTEPILPDIHPLHRRTAESLARLPTSFSSPHYITLKPASKEPRGTADPNPSAKVSLKLDIQNGCASLS", "length": 725 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QM02-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100623139", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTGGENTTNITAFVLLGFSDFPHIRAALFVVFLVIYILTLTWNLCLIVLIRMDSHLHIPMYFFLSNLSFIDICYVSSTAPKMLYDFFQAKPTITVVGCAIQYVVFSTMGLSECGLMTVMAYDRYAAICNPLLYSSIMSPSLCGRMVLGSYMAGLSATLSQVCAVLQLHFCGPNVIHHFFCDMPLMLGLSCSDTFFVRVLTAVFTVIFGIINALVIMMSYVYIVISIMKITSAKGWSKAFNTCASHLTAVTLFYTSGIFVNLNSSSGGSSGLDRFAAVFYTLVIPMLNPLIYSLRNKDIKDALKRLKKRKECC", "length": 312 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QUE5-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524011", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSNVSKFLLLGLPIQQEQQGMFFALFLGVYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFASVTVPKMLMNMQAQDHSISYAGCVTQTYFFMFFACIDNLLLTVMAYDRYVAICHPLRYTIIMREELCICLLAGCWLLSCAYALTHTLLLAQLSFCVDNIIPNFFCDLAALLQLSCSDTSLNELVIYTSGAAVFIFPPSGILVSYGRIGISILRVPSTKGICKALSTCGSHLSVVSLFYGTIMALYFSPSFGQSHYKGIIASVMYTVVTPMLNPFIYSLRNRDMTLALEILIRNKNLFTT", "length": 313 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2QWK6-1", "protein_name": "Calmodulin 3", "gene_name": "CALM3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VSAEREEEGVALKFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYEVTASPVLGPAREGPRASAPSWGGKQPLAIACNQPRRSSGFSWDLPSFENLLSSTLWSPASGDGRGVEHSGRPS", "length": 214 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2R7Y6-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524140", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLVAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINHLSGTKSISFVGCATQYFLFLSLGGAECLLLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIVLISASYVFILHSVIHMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A5G2RGH3-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100524855", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLSQLSLMDLMHVSTTIPKMAINYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYTVLMNRKVGQMMAVTSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYETAVYISDIVLLLLPIILISASYIFILHSVIRMHSAGSKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALRRVLGREMITQNPKVRLP", "length": 320 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A668KLA6-1", "protein_name": "Predicted gene, 52955", "gene_name": "Gm52955", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMGALLANSPLLLCWLVFGAQLSVGEGILLTLTLMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKQCGVFFFALNLALFGIFAFAQCFNPLVYGLHNRDLQSKLYPSLCCQKKLLP", "length": 296 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KLA7-1", "protein_name": "Predicted gene 7582", "gene_name": "Gm7582", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSSEHCNVSDWLRLEATVKASVYVVAFSITTSLTIVIIAIVSQSLQLRKEVRLVLLCHHLLCISSYCGLGVVFQGMWALLANSPLLLCWLVFGAQLSVGEGILLTLTFMALNTYLAICYPLNSPSFVDSAKYRILAGTWTTVILKNVGLFLIEGTSPTPASVFQSAPLCPVILNGMPARVIGMFSLAFLLSVILVSYCLIYREGKRAGHFNKSNIKARRTVLVHLLQISLHVIPTLIIIGLGKRCGVFFFALNLALFGIFAFAQCFNPLFYGLHNRDVQSKLYPFLCCRKKLLP", "length": 296 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A668KM50-1", "protein_name": "RIKEN cDNA A930007A09 gene", "gene_name": "A930007A09Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSLSELPQKNTDLAEMQSGPLGRCSHFFWLGVAFDAVGVAVLFTGVFANLLFYDMLLYLGSIIIFVSLLWWISWYTGNIEALPEDPLRGTSPRESGVHRSGSRRFSLTLRSVSDTFQRIRRRRRRRLHPRVVQRISSISSTDPGQLERNCDARTSGGRALFRSAKPEAVLNQFSRVQTSKSLPLGIVHTGLSICTSRSQPVFSVTSQTYPLASDSNSQMAMSSDSHVYLDSHSQEHSKISVASQIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVATQIYPLEREESQSHFLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASKIYPLEREESQSHLLVIPDSLSMVPVTSQSQILPSVSSESCVPLGPHSQGRSKISVASQIYPLEQEESQSHFLVPMPSDSFPVVPMTSQSQIQGSLAQQSHLQNLPLASQTPETDKASKSHTLAKGVPGVPPGSAQTQHPQASLAQTSQISSPVRKVPKN", "length": 636 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8C2LDI6-1", "protein_name": "Large ribosomal subunit protein eL33", "gene_name": "LOC100774916", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRLWCKAIFAGYKRGLCKQRGHTALLKIEGVYARAETEFYLGKRYAYVYKEKNNTVTLRCKPNKARVIWGKVTKAHGNSGMVHAKFRSNLPAKVIGHRIRVVLYPSRI", "length": 110 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LMV8-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC100755948", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTNTEGKRRGTRYMFSRPFRKSEVVPLAMYMRIYKKGDIVDIKGMDTVQKGMPHKCYHGKTGRVYNVTKHAVGIIVNKQVKGKILAKRINVQMKHIKHSKSRDSFLKQVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPQLLEPISYEFMA", "length": 160 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LSR6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "LOC100751955", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSQDEGEKENPMWELHICKLCLSICVEESRDRLTRAAKVLEQLKGETPVFSKARYTMRSFGIRSNEKIAVQCTVHGTKTEEILEKGLKVQEYELWRNNFTDTGNFGFEIQEHIDLAIKYDPSIRIHGLDFYVVLGRPGFTIADKHRTGCIGAKHRISKEEAMRWFQHKYDGIILPGK", "length": 177 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LUM6-1", "protein_name": "Tubulin alpha-1C chain-like", "gene_name": "LOC100757824", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MCECISIHVGQAGVQIGNACWELYCLEHGIQPDGQMPSDKTIGGGDDSFNTFFSETDTGKHIPRVVFVDLEPTAIDEVRTGTYRQLFHPEQLITGNEDAANNYARGHYTIGKEIIDLVLDRIRKLADQCTGLQGFLVFHSFGGGTGSRFTSLLMEWLSVDYGKKSKLEFSIYPAPQVSTAVVEPYNSILTTHTTLEHSDCAFMVDNEAIYDICRRNLDIERPTYTNLNRLISQIVSSITASLRFDGALNVDLTEFQTNLVPYPRIHFPLATYAPVISAEKAYPTPLPE", "length": 288 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2LZU4-1", "protein_name": "Glia maturation factor", "gene_name": "Gmfg", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSDSLAVCEVDPELKEKLRKFRFRKETDNAAIIMKVDKARQMVVLEEEIQNVSPEELRLELPERQPRFVIYSYKYLHDDGRVSYPLCFIFSSPVGCKPEQQMMYAGSKNRLVQTAELTKVFEIRATDDLTEAWLQEKLAFFG", "length": 142 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2M625-1", "protein_name": "U3 small nucleolar RNA-associated protein 15 homolog", "gene_name": "LOC100755487", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGYKPVAIQTYPVLGEKITQDTLYWNNYKTPVQIKEFGAVSKVDFSPQPPYNYAVTASSRIHIYGRYSQEPIKTFSRFKDTAYCATFRQDGQLLVAGSEDGVVQLFDISGRAPLRQFEGHTKAVHTVDFTADKYHVVSGADDYTVKLWDIPNSKEIQTFREHSDYVRCGCASKLNPDLFVTGSYDHTVKMFDARTNKNVLCVEHGQPVESVLLFPSGGLLVSSGGRYVKVWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTSYKVVHSFDYAASILSLALSHEDETIVVGMTNGILSVKHRKSEAKKESLSRRRRPAYRTFVKGKIYMKQRDDIMINRPAKKHLEWYDKDLKSFRISKALDRVLEPNCVIKTPEVTVSIIKELNRRGVLANALAGRDEKEITRVLNFLIRNLSQPRFAPVLINAAEIVIDIYLPVIGQSPVVDKKFIVLQGLVEKEIDYQRELLETLGMMDMLFATMSRNDSVSLSENVPAELPEKTESPCQPGDTDKNS", "length": 527 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8C2MXE3-1", "protein_name": "Glycerol-3-phosphate acyltransferase 1, mitochondrial", "gene_name": "Gpam", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDESSVTLGTIDVSYLPNSSEYSLGRCKHATEDWGDCGFKTTFFRSATLKWKESLMSRKRPFVGRCCYSCTPQSWERFFNPSIPSLGLRNVIYINETHTRHRGWLARRLSYILFVQERDVHKGMFATSVTENVLNSSRVQEAIAEVAAEMNPDGSAQQQSKAIQKVKKKARKILQEMVATVSPGMIRLTGWVLLKLFNSFFWNIQIHKGQLEMVKAATETNLPLLFLPVHRSHIDYLLLTFILFCHNIKAPYIASGNNLNIPIFSTLIHKLGGFFIRRRLDETPDGRKDVLYRALLHGHVVELLRQQQFLEIFLEGTRSRSGKTSCARAGLLSVVVDTLSSNTIPDILVIPVGISYDRIIEGHYNGEQLGKPKKNESLWSVARGVIRMLRKNYGYVRVDFAQPFSLKEYLESQSQKPTSAPLSLEQALLPAILPARPNDAAESEDTSSNEPRNTADEAFRRRLIANLGEHILFTASKSCAIMSTHIVACLLLYRHRQGIHLSTLVEDFFVMKEEVLARDFDLGFSGNSEDVVMHAIQLLGNCVTITHTSRKDEFFITPSTTVPSVFELNFYSNGVLHVFIMEAIIACSLYAVLNKRGSGASAGGPGSFISQEQLVRKAASLCYLLSNEGTISLPCQTFHQVCHETVGKFIQYGVLTVAEQDDQEDVSPGLAEQHWDKKLPEPLNWRSDEEDEDSDFGEEQRDCYLKVSQSKEHQQFITFLQRLLGPLLEAYSSAAIFVHNFSGPVPETEYLQKLHRYLITRTERNVAVYAESATYCLVKNAVKMFKDIGVFKETKRKRVSVLELSGTFLPQCNRQKLLEYILSFVVL", "length": 827 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8D1BQI2-1", "protein_name": "Uncharacterized protein", "gene_name": "LCE5A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSCQQNQQQCQPPPKSLPKYSTPKFPGPCPPLVSSCCGSRSGHGRCYSSGGGGCCLSHHRRRRYHPCQPQSSNCCDSGGGQQSGGSGCSHSSGGSGCCSGGCC", "length": 103 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8D1VKI8-1", "protein_name": "Uncharacterized protein", "gene_name": "NCR3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARMLLLILIRVHSGSCALWVSQPPEICTQEGTPAFLPVPSTPARGDWPLALSHGTGTNWPQGRRVVVLGQGVRTGNGTPLVVERGPAQLATPTIFLLRAGFYAFGFLSVAIGSTIYYQGKCHRHMGTHCRSADGL", "length": 136 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I5XVN6-1", "protein_name": "SPATA31 domain-containing protein", "gene_name": "LOC689526", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESFLLLMNSAIESWMNTSTMDIATDLSIAILCGVGLFFLLIPFLKDCPLSPASGNKTDIPKDVKRGRSNTRRKTDVEKGCRDGGKTVEETKTPSQPMKILTRQLLQDSTPQIFWNSSQKLDHLLLSQLFSSLTSLEDLILQKFNRRFWGTSSIFSESVVAMAHVLRNPSFPQQKSVRFSDPCVTDQAPSQAQGLRQQHRYHPRLHRQRKTSLVGMTWVPEKKILPISTPKQIHPCLKRRAYGVSCPTTEKGIQTSLPPECLSHKHGLYSKAVKGYVKRNHQKAIGKPPGNWLRDTLKTKAIRPASILSEHLRMFLHHKEPQTKDKATNVEKQQGTCIRSPPSKKLKQFQGRFPPNTDHYCKRRPQLSQPGQPSILNSKSYKLRKIIQSVLAGMTLMKDRADFSMQSQFSQAPQSSVCNAKRYKYSKRMGSVPRRVPLKKDTARYDMGKPIKKCLGAGTKNVPHSACSILGKRLRARNLALKKGQASVMNPTGNYCLHDSKAEMKLASNNTALPVQCRRTPYLQILEALNPIPPGVLASKLPRIVFPSSPICDFKEEYYSKAATVLKNLHHQDPGGTRVKSTSAASLESALSMCSAAKIQKTQRAPPPAASRGLSKAHTDLLKRHLSIQHSALYFEQGRIIQGTGKGSLQQNTNPQKAKHAPLKSFHEGDSRHHSWNGTMVGPGKRVPPAAAKQTKAVEVKKETPYAWSLGSNESHTGKDINISPRVFGSLGAKRSPGHLQTCTPQHSQDSTLRTQGHRNIILCSNKQPQPRPGRHDPECPSTVHPAKVNLSSEHSMSSFQNTCQKPKTAQGSCERADTKENRVLKDKIRINHLKDLCPHKERQGSIRPTAISQGGRLGRSRPCSLSSTQLKDTAKTRTSDKRQATSKSSWKSDIREVLKYGYVGSKDIIGQEDTSKKDQPPAVTERTEEDWTGEKAMCNMIAHLQYLTNFLFEIMEDTEWDPSKLQGCEVESLTFQLGSSSDSSEGDDDINQGTSTSTMSFGQTSPEMHNCSFTKTGIGDKTQSEIKAKTACDQHLNQVNRGMFSDQLPMPKEYDLSCRYRGIQHQQELGLPDQTFYQYKLRMTHCPHGGTKGHNYSFGYRKLGDQQQPDFTHKALDPHQSAKEDMGCVSCLSPKGSRPVKHRRTDCFSP", "length": 1151 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5XWP3-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "ENSRNOG00000063695", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRDMCHMTPYRLLCVLVALALSGCNVAQEVTQVQSTASRQEGEEVTLDCSYETSYVAYYLSWYKQHLSGDIIFLIHQISSSTAEERSGRYSLVFQKSLKSISLVISASQPEDSGKYFCALSDLTQC", "length": 127 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y4M0-1", "protein_name": "Large ribosomal subunit protein uL14", "gene_name": "LOC108350588", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEQRRGGSSGAKFRISLGLQVGAVINRADSTGTKNVYIISVKEIKGRLDRLPAAGVGHMVMATVQKSRPQLRKKVHPAMVIRQQKSCGRKDGVSLYFEEDAEVIVNNKGKMKGSAITGPIAKEHADSWPRIASNAGSTA", "length": 140 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y5C9-1", "protein_name": "Ribosomal protein L32 like 2", "gene_name": "Rpl32l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALRPLMKPKIIQKRTKKFIRHQSDRYVKIKRNWRKPRGINNRVRRRFKGQILVPNIGYGNNKKTKHMLPSCFRKFLVHNVKELEVLLMCSKSYCAEIAHNVSSKNRKAILERAAQLAIRVTNPNDRLCSKENE", "length": 135 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y6V7-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "Pate4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNTEPLFDIVINCPIAPQFILKILLFPYPANTNLICNTCNRSENSECKNGTGQCTAPEGGSCSTISIYHGQRHVLSKQMCLGHCEEKPHYNGDFMIYVMCCSKNLCNSF", "length": 110 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5Y7P1-1", "protein_name": "Heterogeneous nuclear ribonucleoproteins A2/B1", "gene_name": "ENSRNOG00000069815", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEREKEQFCKLFLGGLSFETTGESLRNYYERWGKLTDCVVMRDPASKRSRGFGFVTFSSMARPHSIDGRVVEPKRAVAREESGDPGAHVTVKKLFVVGIKEDTEVHHFRDYFEEYGKIDTTEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSGQEMQKAQSSRSGRGGNFGFGNSRDGGGNFGPGQGSNFRRGSGGWESSDGYGSGRGFGDGYNGYGGGTGGGNFGGSPGYGEGRGGYGGGGPGYGNQDGSYRGGYDNYGGGNYGKGNYNDFGNHNQQPSNCGPMKSGNFGGSRNMGGPRDEHRSFPSWKGYNGVFGKQSPLTWIKTHSL", "length": 347 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZKP8-1", "protein_name": "Glycerol-3-phosphate dehydrogenase [NAD(+)]", "gene_name": "Gpd1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGATTLRVCIVGFWSWGSAIAKIIGTNVKNQQKFASTVKMWVSEEAVNGRKLTDIINHYHENVKYLPGHKLPENVVAVANLSEAVQDADLLVFTTPHQFIHKICNEITGRVPKKALGIIHMESIDEGPRGLMLISDIIREKIGMDVSVLMGANTAREVAAGEFCETTIGSKVIQNGILFKELLQTSNFCITVVDDADAVELCGALKHIVAMGTNFCNGLHCGNNSKAAVLRLGLVEMITFTRIFCKSQVSTTTFLESCGFANPITICYRGSDCKEAKTFPRIGKTMGNLQKEVLNGQTLQGLKTSALVYQFLKQKGLLAKFPLFVTVYRICYEGRPSTEILTCLQNHPAHM", "length": 351 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZL63-1", "protein_name": "Ankyrin repeat domain 13a", "gene_name": "Ankrd13a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSDQSRKAAAEGGSSPMVWSRPARAPPGGRADGRGPIVERTTGEGRAGDESRRARTVGFVRGDLGLPKGPAVPQNGGGRVSRRGGLVGRHGAGLGPFRKSGPPPRSVMERLAYFPVRGGSAGSSRFASCQRGRERAGRGVGAAERVPEPVPSPARDPGPPAPPAPDSEALVVRCARHLAARRSPPLALRPVGRAPETPSGGSRLVAGGRSGLGGDLLAMSSARDTSSRFPLHLLVWNNDYRQLEKELRDQNAEALDPRGRTLLHLAVSLGHLESARVLLRHKADVTKENGQGWTVLHEAVSTGDPEMVYTVLQHRDYHNTSMALEGVPELLHKILEAPDFYVQMKWEFTSWVPLVSRICPNDVCRIWKSGAKLRVDITLLGFENMSWIRGRRSLIFKGGDNWAELMEVNHDDRVVTTEHFDLSQEMERLTLDLMKPKSREVERRLTSPVINTSLDTKNVAFERTKSGFWGWRTDKAEVVNGYEAKVYSVNNVSVITKIRTEHLTEEEKKRYKEDRNPLESLLGTVEHQFGAQGQDLTTECATVNNPTAITPDEYFDEDFDLKDRDIGRPKELTIRTQKFKATLWMCEEFPLSLVEQVIPIIDLMARTSAHFARLRDFIKLDFPPGFPVKIEIPLFHVLNARITFGNVNGCSTAEERQSVEGTQAECAASDATNFEVDQSVFEIPESYHVQDNGRNVHLQDEDYEIMQFAIQQSLLESSRSQDLSGPASNGGVSHAHSYEAQYERAIQESLLTNMEGRCPGGLSDSSRFDSDLRLAMELSAKELAEQELRLQEEEAELQQVLQLSLTEK", "length": 809 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZP24-1", "protein_name": "Large ribosomal subunit protein uL30", "gene_name": "ENSRNOG00000064315", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAVPEKEKKVAAVPGTLKKKKVPAVPETLKKKRRNFSELKVRRLRKKFALKTLRKARRKLICEKAKHYHKECRQMYLTEIRMARMARKAGNVYVSAEPTLAFVIRIRGISGVSPKVREVLQLLRLRQILNGTFVKLSKASVKMLRIVEPYIAWGYPNLKSVNELIYKRGYGKIRKKRIALTDNSLMARSLGKFGIICMEDLIHEIYTVGKHFKEANNFLWPLKLSSPRGGMKKKTTHFVEGGDAGNRETR", "length": 251 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZPV0-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "ENSRNOG00000066253", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIVQRIFRLSSVLPSAVSVHLRSNPGVTAVAFNKEPDPVQKLFVDKIREYKTKRQVSGGPVDTGPEYHQDLDREPFKLKQLYGKGEMDKFPTFKFEDPKFVVIDKPQS", "length": 108 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZRI3-1", "protein_name": "Natural killer cell cytotoxicity receptor 3 ligand 1", "gene_name": "Ncr3lg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASQSCQRGPENAHMHPKGPCCSALCFLCSLGSSPHGSSLGPLRKCGRRSKPVQSSPEGSRVAEWPDGLLSLLLLLWSLLPSAGGLELEMAGTTQIVFLHEDVTIPCKILGSLHLDLSIVGVIWSLKKDGDESEVFKFYGDQLEAVRPGANVSLLGLEHGDASLYLPRFELWEAGEYQCKVVVTPEKKEGTTRLEVVAHPNMSLSEKPATARGGKEKLIICQLDGFYPEALDIKWMGSALKDSHFQEITEGVVTGPTVKNDDGTFSVTSSLALKPALEDHMYQCVVWHRSWLMPQSLNVTVFENTRDSTHGTVPPTAEVGPPVSEPRSVMIYVTIIGLCILLFSVIVCGLWKWKRLTTSNTGLCLRLDVRC", "length": 371 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZS91-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134482834", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETEEELPTPTPKPSISEEGNFHSQYQVLGTSGQGGNGKVLLAHNRLTGTPVAVKVLRKDKQWFQPAMMEANIMRKINHPNIVSLIQVIEKETRIYLIMELVEGQELYQYIRESGHIEEDEARQIFEQILSAVSYCHGKGIVHRDLKLDNIMIDKNKKVKVIDFGLSTQFPPGKMLNHHCGTHSFGSSELLLGHRYDRPKNDMWIIGVVLYCMVVGKLTFDSVIIQDLQRQVVAGVYPAPCGVSKELEDLLSKLLRVNPNFRPTARKAMKHPWFKEHWNGLIVPYEELLPLTPDPAILDAMKSIGLQASVVKHTLKQRKYNEEMATYFFLQKQALQGDGCTAQAQQVSPVAAPFPSLDPAAAFRLEPKRSGSLPVLGTLRVSSSHGHVSHYGQNAHPKGGKRYTVAGRLRPLPMTPTQDHYHKCAVSVPCIQTTSIFSEKSSNKKIKEDNPLSHRAPLEDKPIPSRVRHRGFKGWTRNIANALIKLCCCMPRRKKPRLGQNRISPQK", "length": 509 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZT61-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "LOC134479845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDITSIKKTLGSQYRVAFFLGQGSYGSVKLAWHRRTQALVAIKTVEISKNTIRAILSEMTTLELLHHPNIISLFQILVTANQIHFILQYAPGGNLVQLISEEGPLPEEKAKKMFGQIVSAIRHCHSLDIVHRDIKPQNILIDGEGNVKLIDFGLAVKCRPGTLLSRHCGTRGFNAPELVLRQPYDGKSSDVWSLGVLLYFITTGYFPFRGNTIDEIEQKITTGTYTVPHHLSGQLENLIHQIFTVSPEMRPSIEEIENHPWIKKCELKIPPMSDPDYKIIEMLCGMGYNAKDILESLQKKRYDEPMGAYLSLKNHVSEGYDLASITPTKPGDPCPPPPPSPAHPSVFGLPLRRRASEPNFGLLHRQPSREQNPLDLILSGLNMGRCVSMPPIAVYYPKKQRSTSTRALHSRPVASPCVYNNMLGVEIILPHKQDIEMNTSSPPQTMGWFKRLRKGIGDCFSRLCCFPRAPKKKTQHRSSKRVAPLKKAASSTI", "length": 493 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZXB5-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLSSLPGRNLAMARLLLLLLSAACLHTGNSAGYQEKNDFGVDQPDVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKHYHGEFIYTSTRPFIHEHFKGRLIMNWTPGQTSGVLRILNLKENDQATYFSSVFLQTPEGMKLWQSIPGTKLIIHALDTTMRSPSIIPSVVPTDDLEYTQGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZY57-1", "protein_name": "40S ribosomal protein S26", "gene_name": "LOC134478821", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPGPRRPRQEAGSKPRELQQRVLASVKRRCLFSSLGSNTTKKKRNNGRAKKGHGHVQPIRCTNCARCVPKDKAIKMFVIRNILEAAAVRGISEANVFDAYVPPKLYLKLHYCVSCAIHSKVVGNRSCEARKDQTPPPRFRPSGAAPQPPPKPM", "length": 154 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYE5-1", "protein_name": "Oligosaccharyltransferase complex subunit", "gene_name": "Ostcl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METKHSALLRTFPFLVLECPNLKLKKPPWVHMLLAMTMYALVVVSYFFITGGIIYDVSIEPPSVDSMTDEHGHQRPVAFLARRVNGQYIMEGLASSFLFTMGGLGFIILDRSNTPNIPKLSGFLLLFDFVCVLLSFFIARVFMRMKLPDCLMG", "length": 153 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYN2-1", "protein_name": "Non-selective voltage-gated ion channel VDAC2", "gene_name": "AABR07051831.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAECCVLVCPRPMCIPPPYADLGKAARDIFNKGFGLGLVKLDVKTMSCSGGEFSISGSSNTDTGKVSGTLETKYKWCGYALTFTEKWNTNNTLGTEIAIENQICQGLKLTFDTMFSPNTGKKSGKIKSAYKRECINLGYDVDFDFDFGWLAGYQMTFDSAKSKLTRNNFAVCYRTGDFQLHTNVNNGTEFGGSIYQKVLCEDFDTSVNLAWTSGTNCTRFDIIAKYQLDPTASISAKVNNSSLIGVGYAQTLRPGVKLTPSALVYGKSFNAGGHKLGLDLELEV", "length": 284 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZYX3-1", "protein_name": "Methyl-CpG binding domain protein 3 like 3", "gene_name": "Mbd3l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LGELGNAGRLTGSMIPSRLQKRRKIQVAKSKRKAKHKSGTTLRNPLRLTSCIFPQPVTVITSYPENKTRYRRDEAKLKKPQQLCALERLKNFQFGGDSKENLSCPLELANAVERIARGMQDEASNQSGDKDQLTSGQVTSDQPPYLETNEHVALQLSPSFSSQGVTLPVPLHLSPSYFLRKVTTGDIQRQAWKVKKARKRLAEALEADRLARQTENMRE", "length": 219 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZU9-1", "protein_name": "Keratin-associated protein", "gene_name": "ENSRNOG00000070302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "SPSTCELSSSLHSDCQETCIEPSICQRSCVASSPCQMPCYYPRSSTACSPCQGTYDGSMGVGSNSLKSFGGFTGSLGYGNSGFGSFGFGSCGIRSQGFGCNFHRPGYFSSKSVQSSYYQPGYTSGFC", "length": 127 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I5ZZY5-1", "protein_name": "Ribosomal protein eL8/eL30/eS12/Gadd45 domain-containing protein", "gene_name": "ENSRNOG00000064452", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKIKAVTEESEAQGEGCSQQHRYQELLVYLNPIAQHPGFPPPDLRKIEKGKKKKKRRPTKQKQIRHGVKEVQKFVNKGKKGIMVLTGDTLRGTAIFQLCARTRICPTSIFPLTDLGAAMGSKHPTCVIMVKLHEEYHEAYDKCLEEVQTLATPL", "length": 155 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A2Z7-1", "protein_name": "Developmental pluripotency associated 1, pseudogene 1", "gene_name": "Dppa1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMPPQVLISGLLLLLPAAWTTTVTSSDQLWNNHTEVVPTQSPLKISTKDLYIGTSVSAALLILLAGVLAVLKYRHRRKKILESAVVFHGFQNGVFQSTEQSQAVDVYVIEDSKVPVAH", "length": 118 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3D9-1", "protein_name": "Small nuclear ribonucleoprotein Sm D3", "gene_name": "Snrpd3l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSIGRPIEVLQEAQGYMVTRETITGEVYPGKLIEAEDNMNCQMSNITVTYRDGPVAQPEQVYICDTKIRFPILPNMLKNAPVLENLKNKNQGSRAGQGKAAILKAQVAARGRGHEMGPWKLPEAKTVFSIKENFPSCLLLGF", "length": 142 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3N0-1", "protein_name": "Uncharacterized protein", "gene_name": "Pramef20-ps2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQTPPTLEKLAIQSLIRNEDVAMSSLGELPAVLFPALFKEAFTGKHINLVKEVVAAWPFPCLLVGALMKTPNLETLQAVLDGVDMQLTRKFHTRRTKLQVLDLRNMHHYFWNIQAGEEDSSCSAENSKEKKVVKVFHRYALRKRVKVIVELYIHSCLKEEQTCLLKWAQQRKGSLHFCCTKMKVWNLSLCGIGEILKVFDPQHITELELHTEWTLLELAHFAPYFGQMRNLQKAFLAPLHRIMFSNSNGKRDREAKCIKKFISQFSKFNCLQHLHMFCVHFLRDHMNQVLGCLMTPLTLSITYYLISQKDLDSLSRSQSLFQLKHLDLRGVVLCDLDIMPLRGLLEKVADTLETLDLQWCKMTDSQLYALLPALRHCCQLTMVNFYSNNFSVPILKDLMQHIANWSRIRVQQYPAPLECYDDLAQVSVKRFAKLSSELMYTLGVIRQTKNISFATDICHTCGQRCVYHNGSRLCCCWH", "length": 480 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3R7-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "LOC120093241", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARKALTVVAVLGSGAGVGSILFALVTPGELQKQLMLQEMPERDSRRRDAAVRTKELVMATLKDAAATKENVAWRRNWTVRGDGRSA", "length": 89 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A3T5-1", "protein_name": "Large ribosomal subunit protein mL62", "gene_name": "Mrpl58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EHGGRLGPTLEPEPSWNLVAPAARALCSPDSAQTGERHRVQEHLQPGQAVPRIQGRGYRLEGPGEPRKAGRKGRFLLLLDRLSISYCRSSGPGGQNVNKVNSKAEVRFHLASADWIAEPVRQKIALTHKNKINKAGELVLTSESSRYQFRNLAECLQKIRDMIAKASQVPKEPSKEDAQLQRLRIEKMNRERLRQKRINSTIKTSRRMTMD", "length": 211 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A478-1", "protein_name": "T-cell activation Rho GTPase-activating protein", "gene_name": "LOC134485907", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGEIHRTLLCQGPVELTSGRKRNKRYLSLFDDVLVVSTNLTKKKFKIKCIIPLNYLWVVDDVELVRANQTCTCKTIFFYWATGNALATFRSKEQKVQWYTFLTRSINEAKKGIKKTFPLHIFPEDIQTCDSSLCVTATNMDTVNDIMEKLLPMIRVHNIEDYQLWFSPGHKETPRALQGHEYPYDIIMNNVQNNLSKSNSKIFTAFPPLPGLFMENQSWDTGGQFILKPRDSAGSQQQDAKERPRKSCMTSCFHGGSVPHHDQECSDPRDDKRGKLFGQDLSSICQDGKLPTIILDMLSRIKDKGPTTDDIFLITPNGSLCKTIKEKLDNGENVDIYQQPVHVVAWILKEFLQSIKGSLLTSKLYDQWLIVPEKVNDKEKLAAVKSLLEKLPKPNADLLRQLFRILHQIKTNSSVNNMSSFRLSLETAPCILWLPSYRNNILTNDIAKKISLVTFMIDNSPELFGEDIVAVWYETSLYHPPGLKYPCSQNTPSSNGIMEETEHGLSSCPGERTCTPDFDELPRSGAAASIPYEGILASEKGEGNESTTQPEPVQNSPTPQTKKELGNCSPNILKDVNVPAVILDMLSVIAEKGQCSDDIFRMQSEKSHWSLKEKVNTGKHVNLKEESVLTVASVVKDFIKNIEGSLLSCDLYENWLSIPDEGPLLGKIASIQNILLKMPKPNYVLLKQLICVLQKIKAASTNQLDTFDLSVRIAPHVLWNPTCKTLFGRDLSKKLSIIKFMIDNCQELFGENDNIFCEDNQKSYDINLSSDTLNTSGKATLMIETIDDHDVKTSKSNTKKLEMSSAVPHEGGPTAGHNGTTSKYNVPQEKILHD", "length": 834 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4C1-1", "protein_name": "RRM domain-containing protein", "gene_name": "ENSRNOG00000063783", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LTCCAINSDPHPDSGLKMEGHDPKEPEQLRKLFIGGLSFEATDDSLREHFEKWGTLTDCVVMRDPQTKRSRSFSFVTYSCVKEVDAAMCAQPHNVDGRVVEPKRAVSREDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIKTMEVMEDRLIDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGRGGNFDGRGGYGGGGGGSRGSYVGGDGGYNGFGGDSGNYGGGPGYSSRGGYGGGGPGYGNQGGGYGGGGGGYDSYNEGGNFGGGNYGGGGNYNDFGNYSGQQQSNYGRMKRGRFGGRSSGSPYGGGYGSGGGSGGYGSRKF", "length": 350 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5E5-1", "protein_name": "Paired immunoglobulin-like type 2 receptor alpha", "gene_name": "Pilrb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQILLLLLSATCLHTGNSGGYTRKNYFGVNQPAVLSGVQGGSIEIPFSFYFPWKLAKDPQMSIAWRWKEVHGEFIYQSTLSFIHEHFKDRLILNWTQGQTFGVLRILNLKENDQATYFSQVCLQTTEGMKCWQSIPGTKLIVTHGVICSLLISPQLSYDHEDPLHHHLCRPHSWPGEHKGPKESFTAEPGGHHWDGRGQSCSHHPPLRMDDLSVVEAKASRVTPKPQPE", "length": 230 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A5T5-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "Rpl21l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRGTRYMFSRPFRNHGVIPLATYIRIYKKGDIVDIKGMGTAQKGMPHKCYHGKTGRAYNVTQHAVGIIVNKQVKGKIPAKRINVRIEHTKHSKSRDGFLKRVKENDQKKKEAKEKGTWVQLKRQPVPPREAHFVRTNGKEPELLERSPYEFMA", "length": 160 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A8T3-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RMNCSQAPGFILLGLSRDPEKWQLFFSVFLVLYLLGLSGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKILQTLWTGDGSISFSGCLTQLYFFAVFADMDNLLLAVMAIDRYAAICHPLLYPLLMTPCRCGVLVSGSWGVAHCVSLTHTLLLSQLYFHTNQMIPHFFCDFGPLLLLSCSDAHLNEGLMMALAGVFGISALLCIVSSYSCIFYAVARVPSAQGKRKALATCSSHLSVVLLFYSTVFTTYLKPPSSSYSSGEVVAAVMYTLVTPTLNPFIYSLRNKDVKSSLRRILNMVKSPD", "length": 310 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A969-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000067430", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFFLFWTFPGLELDKLALLSFESSSSIHPRACASTPAFQRSHNPGDAAQQEAKQREAEMRNSILTRVLDQSAWVRLSDLALVKPDKTKAVEHRVQMARYGQLSGTVSEQGFIETPEKVSQQTEEKATVKFNRREVTDSDEDDDY", "length": 144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A9H4-1", "protein_name": "NAD(P)(+)--arginine ADP-ribosyltransferase", "gene_name": "Art3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQATARGVIKRKAFPGRQLSLSTTSCPGGKITPAESGNRFESGHHLNVLQRHKRQKRKMKMGHFELVTTLLAAMVLMDVFQVQAEVLDMAENVFDDEYLKCNSRMEMKYIPRMHGEELANDELLQSVWDKAGIQWEAQKAQLSLPKNFKDAYGIALTAYVTEAQDQSPFYHTFNRAVKIAGLSRRRYIYNFPFKAFHFYLVRALQLLRRPCEESYKNVVYSTSPNISFAFGEQNQARLGNFTLAYSAKPQTANEQRLLTIQTCFGVAVGKLLNKESEGIVLIPLSEVFQVSRKGTDDDLILHSINSTCSYYECSFLGGLKAGSCTTNPENPDPGYLNNPDLDSQKLEDSGRKSLDSVKMPEIKVLQGEENPLLPDEKPEDRNRGKANVPTPGLVPVPGPKSHPSSSSGHRLLPSDTASTILLIAAAVDFIAL", "length": 433 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AA84-1", "protein_name": "Ankyrin repeat domain 10", "gene_name": "Ankrd10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAGAGAGVEAGFSSEELLSLRFPLHRACRDGDLVALCSLLPHTPRAHLAAEDSFYGWTPVHWAAHFGKVGAGTLRRHFPRGVLLGSERTPPCLESAATARSAPPAPPEGSRAHVQQSGLGVKGWGRGGAEAALAPPGVQGACAAARSPGPRGARGVMGGGAEMGSVWPAPRRTQGACAHLWLFRAGRADRMQLRRFARRPSGFGEWCGRLLLEARREPGASRSCLMETGRRAPLRHKGMDAALAAGGVRSAPAVVDGGLAARPTGPLSQLGPPCLECLIQLVRAGASLNVSTTRYAQTPAHIAAFGGHPQCLVWLIQAGANINKPDCEGETPIHKAARSGSLECISALVGNGAQTDLRNASGLTAADIAQTQGFQECTQFLLSLQNHQMSRFCPNGTLSGGHENILPNHINLGTNRKRCLEDSESLGVKKARTRVPSLDHTMPLANGDAEDDADRMHVDREFAAVSDMKNSSSVLNTLTNGSVINGHLDFPCVAQLNGMESRSDPCLTGSNGISNGQPFPSGQGPVCANGTEEPEKTMGVNPEMCGSLHLNGSPSSCVASRPSWVGDIGESLHYGHYHGFGDTAESIPELSSVLEHSSCVRVEQRYDSAVLGAMQLHHGS", "length": 621 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ABF4-1", "protein_name": "Nuclear transport factor 2", "gene_name": "AABR07018058.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDKPIWEQIGSSFIQNYYPLFDNDRTQLGAIYIGASCLTWEGQQFQGKAAIVEKLSSLPFQKIQHSIMAQQYQPTPDSCIISMVVGQLKADEDPIMGFHQMFLLKNINDAWVCTNDMFRLALHNSS", "length": 127 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC04-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSQNKTLKSIEEVALHVILLCQVGVGTVANFLLFIHNFSVILTNCQLTPIQVIVTNLAVASAFNLLLLAFPNNVTLFVPRKAPSDLSCKLWYFICLVARSTNLSSTCVLSTYQFVMLLPGNWSRVILKGRAPKIVNYSCYGCWIFSVLNNAYIPVKVSGPQKTQNDTDFKDKWVCSTSGFSVGMSFLRFAHDALFISIMIWTNVSMVILLNRHHHRLQHIHSSNQDHRAYADTRAAHTILMLVVTFLSFYLLDCICTFFHISFVDSRLLLRRIKEVLTASFPTISPFLLIFRGPKNPCSLLSRS", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC51-1", "protein_name": "Non-histone chromosomal protein HMG-17", "gene_name": "Hmgn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAEGDAKGDKAKVKDEPQRRSARLSAKPAPPKPEPKPKKAPAKKGEKVPKGKKGKADAGKDANNPAENGDAKTDQAQKADGAGDAK", "length": 90 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AC66-1", "protein_name": "Eukaryotic translation initiation factor 6", "gene_name": "Eif6-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVRASFENNCEVSCFARLTNTYSLVAIGGSENFYSVFEGELSDTIPVVHASIASCRIIGRGTSVWGTGMGYWYPTTTTDQELQHIHDSLLDSVQIRRVEEGLSALDNVTTCNDYVALVHPDLDRETEEILAGVLKVEVLTVADQVLVGSYCVFSNQGGLVYPKTSIEDQDELSSPLQVPLVAGTVNRGSEVIAAGMVVNDWCAFCGLDTTSTELSVVESVFKLNEAKPSTIATSMRDSLIDRLT", "length": 245 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ACC5-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000069094", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LPLLAFEKYVVCDGELQRLQVSCEVLGDVDPPQRLSASVVQMKQSVVEFLGTLVEQDAQGAAEDMDNALVGDNEEAEGENNSTRTNSDGPFTERPNQRLNNR", "length": 102 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AEL7-1", "protein_name": "Protein phosphatase 4 regulatory subunit 3C like 1", "gene_name": "Ppp4r3cl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKLYRVKVYVMMEDKQWKDIGAGQISSKYIDRLQGVCLLVHSESDGSPILECKIQPNVPYQKHQGKVIIWSEAKNHGTAIHFQEPNDCQETWEVICQVQGKDPNVEITQLLTDDLESFKDMLLSWNKVEMSSCELHTLENIADLLSFVNEAPSHKKILTLVLEKEGYIKKLLQLFKTCEKHQNIDGLHYLNNIIRGILFLDNIHLFNIMFSDEFIMDVVGCLEYGPGLDEPKQHRQFLTQNVKFKNVMQITHSQLRKKIQQTYRMQYIYDIVLPTPSIFEVNLLHDLSTMIFFNKIEIITMLQEDEHFLLEVLAQLKDNTVSNERRHELLLFFKEFCAFAKTLHFQKKNTLLKTLIKLGIISALKVVVHMHDYQIQVAALELFAHLVEYSPRLIRAYAMKEAQYSEDNDGLLINIMIKQMTCDSDPEFSRSIILTTVLHAILDPENMRVTTKGHERRKFLNYFYRHCMNKLIEPILSITVENNSDDNRVNICPDNYQNAQLLGAILEILTFCVQYHSKYVKNYIISKNLLSRILILMSSKHTFLILCAVRFMRKMIGLKDKMYNLYIVEKNLFEPVVNAFMHNGHRYNMLNSAIIELFEFIRQENIKSLIANIVEKFFMFFESIQYVQTFKGLKTKYEEEKKKKRERQLRKSLHNIIYQRIYCRHIKAMEVKVKADIFCRQITDKEEEREKGGGGGEGGGGRGGEGEGGREGGGREGEGGGGGKGGRGEGGAVLSMGSDIPSHYDMFVKINEMNERENVIECRKRKSSATSEYSTSCGDTSDNGISTVYCSSLVPLVDYAYDTDGEDDDGSYGNNENEEEEEEEEEEEPPKKKPYFHP", "length": 840 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AFG0-1", "protein_name": "Cytochrome b5", "gene_name": "ENSRNOG00000064959", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFAKEKGKFEDMAKDVKCYTLGEIQKHQDIKNSWAMLHHRVYDLTKFLEEHLGEEEVLRERAGGHASENFEDVGCSTNVQGLSKVHIIGLFHPALITTIKLNSNWWDQLCSPTSQVVVAHTFNPSTREVGAVGFP", "length": 135 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGM4-1", "protein_name": "Proline rich 18", "gene_name": "Prr18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRLLGRVMSFSPMPPPPPPPPPPARTQGGPAARQLSRRPCGPPAASPPAPAAAAAGEKKRRPPEMLLSSSWPSATLKRPPARRGPGLGPGTPQPPTSARVPPQPSPGRGGTSATCSAPRRIACSHIPAGSTASGTSAGAGAGPEDATRFSLSLTPEAILVIQRRHLEKQLLARPRRPFPAPSADPRRPLVPCPRTRSSTLRRGGPTSVPDAPLAVAVSSRPPRASLLPGGLQATMPSPRPSSLRPVLKVSLLNEKHKYDDEEYEEEVEVVDEGLVRKCTEWLRGVESAAAARGRTGHLDSLPHLSTL", "length": 308 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AGS9-1", "protein_name": "Olfactory receptor", "gene_name": "Or5aq7b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVWNSTGVKEFILIGLTENPNWQVPLFLLFCIIYFIILVGNCGMIFLIWLNVQLHTPMYFFLSNLSFCDICYSTIIAPKMIINFLSEHKSTRLFACILQSFFFAVYATTEVVLLSMMAYDRYVAIANPLMYTVIMTQSICTQMILASYLTGLINSLIHTIGLLKLNFCGPNIVNHFFCDVPPLLKLACSDSHINEILLLVFSGIIAISTLIIVIVSYIHIIIAILRIRSAMGRGKAFSTCASHLTAVALFYGSLTFSYIQPSSQYSMEQEKVSAVFYTLVIPMLNPLIYSLRNKDVKEAAQKLMLGKRNAC", "length": 312 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AIA3-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065493", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIFVPFFPHPGSIRKDGVVYAHTMENSSNSPRETREPAPLRRTWRGCFQRALPRVSKFFRRGRGSTGGWDNGSPRQGPMHSDQDLRHLRSLLSKESCPVMSK", "length": 102 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK52-1", "protein_name": "Olfactory receptor", "gene_name": "Or9s14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAIEVHRNGSLSAMSLQGFVLLGFRGGAETQALLFTVFLVLYVVTVLGNLTMIMVITLDARLHSPMYFFLKNLSFVDLCLSTVVVPNALASIFFSSKTISFAGCATQFFFFSLLAATEAVLLAVMAYDRFMAICSPLRYPVTMCPMTCVRLVLGTFCVACLNSIVQTSLTFRLPFCSSNRIDHFYCDVPPLLQLACASTALNELVMFGICGFIIVCAVFVVIISYVYITVTILRMHSGSGRHKLFSTCGSHMTAVSLFYGTGFAVYGQPGGVASMEQGKVVSIIYILIIPMLNPLIYSLRNKDVKDALRRLGQRHSLAKESG", "length": 322 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMC4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "ENSRNOG00000068014", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCVFKNAWGHRNMCSMALCSQFGTHLHVSLTDAHSLSCNLIIRSPTKAEPLRYEGHCSMDEIVFLSFNNVNKTMPLGNQEKMANATKVQKCLTQWIDLLGQDLRDKVSEIKVHTTKTSGHPTLRVTMLSKHRHGEIIGASWEFNISENYSFILDLKTMKWKPQDIMKEWKDDETLMKHLNLSIVECSQKFNEFLNQHEERTSRYYLDSALPPAPPPLFKGFTILLWHSYTPAISPTSSDTHSSFINFRDGLIDINFPL", "length": 258 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMN7-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "ENSRNOG00000070681", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPGYITLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLACAEKKAAGKGDVSTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVLYCIIKGKARLGRLVHRKTCTTVVFTQVNSEDKGALAKLVGAIRTNYNDRYNEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AMX9-1", "protein_name": "Ribosomal biogenesis factor", "gene_name": "Rbis", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKNKLKGQKSRNVFHIASHKPLKAKNKAKPVTTNLKKINIMNHEKVNRMNRAFVNIQKELANFSKSLSLKSVQKELHHEKEPANVDEATRLMAQL", "length": 96 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ARJ3-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "Or8b101l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLGNVSSVKEFILLGLTQQPELQLPLFFLFLGIYVVSVVGNLGLIVLIVLNPHLHTPMYYFLFNLSFTDLCYSTVITPRMLVGFVKQNIISHAECMTQLFSFCFFVIDECYILTAMAYDRYAAICKPLLYQVTMSHQICLLMTVGVYMMGFVGAMAHTGSMLSLTFCEGNIINHYMCDIPPLQKLSCTSTSINELVVFTVVGVNVIIPTLTLFVSYTLILSNILSIHSAEGRSKAFSTCGSYIIAVSIFFGAVLFMYFKPSSASVDGDKVSTIFYTILGPMLNPFIYSIRNKDVHVALRRTLKKRIFT", "length": 309 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6ATM0-1", "protein_name": "ELAV-like protein", "gene_name": "Elavl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKDAGAGSCRYKGLGAAAVRPRARSAQRGPVGGREGGREERTHYPAPDRPDRGPAAEGRAAEISVGKSDFCGPRGAALRAPSTARPLPPSTCRQGSGRRSAHPQARVSSRPSRAPPPPSSPLRRPQSQTPGRDPGVSTRRPPRSARPPEPPSIRTAPAGHTRMVTQILGAMESQVGGGPAGPALPNGPLLGTNGATDDSKTNLIVNYLPQNMTQDEFKSLFGSIGDIESCKLVRDKITGQSLGYGFVNYSDPNDADKAINTLNGLKLQTKTIKVSYARPSSASIRDANLYVSGLPKTMSQKEMEQLFSQYGRIITSRILLDQATGVSRGVGFIRFDKRIEAEEAIKGLNGQKPLGAAEPITVKFANNPSQKTGQALLTHLYQSSARRYAGPLHHQTQRFRLDNLLNMAYGVKRFSPIAIDGMSGLAGVGLSGGAAGAGWCIFVYNLSPEADESVLWQLFGPFGAVTNVKVIRDFTTNKCKGFGFVTMTNYDEAAMAIASLNGYRLGERVLQVSFKTSKQHKA", "length": 522 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AUS4-1", "protein_name": "Ubiquinol-cytochrome-c reductase complex assembly factor 3", "gene_name": "ENSRNOG00000062467", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTAAGKTLAVVAVLGAGAGVGSILFALVTPGELQKQSMLQEMPERDSRRRNEAVRTKELVIATLKDAAATKGNVAWRRTGQLEGQGRMCGTKGTNKCSLPIKWISQLDI", "length": 110 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AWY6-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000065059", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKATKKSKNTTSDVEPSTSSAKSKKAKTCYQYQTRAGEKKSRWSGSDCSVNVQKTTKKAKRTLPRIAENNTSEKTVPPTKKTKRAKDEQLFGHYHRLMDEISTSTERGPEQSSTDSSSASTSDEESQ", "length": 128 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B5G4-1", "protein_name": "protein-tyrosine-phosphatase", "gene_name": "Ptp4a1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARMNCPAPVEVTYKNMRFLITHNPTNATLNKFIEELKKYGVTTIVRVCKATHDTTLVEKESIHVLEWHFDDGAPPSNQIVDDWLSLVKIKFPEEPGCRIAVRCVAGLGRAPGLVALALIEGGMNYEDAVQFIRQKRRGAFNGQQRLPLEKYHPKMWLRFKDSNSHRNNCCIQ", "length": 173 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6B646-1", "protein_name": "Ankyrin repeat domain 66", "gene_name": "Ankrd66", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSREARLHHQTPGDQEAGAACLLSWGGGGASFHGVNTLTLRPAMMACSTELLKDTDSVMELSKLSDMTKLHQAVAAGDYNSVKKILKKGLCDPNYKDVDWNDRTPLHWAAIRGQMEVIHLLIQYGARPCLVTDVGWTAAHFAAESGHLNVLKTLHALHAAIDAADFFGDTPKRIAQIYGQKDCVDFLDTAEPECRDHRQRGLLFDERDPDWDLKKRELELSLPVPDQNTNKKKKRIRGSTRVNHSKAWRI", "length": 251 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G1V0-1", "protein_name": "Ankyrin repeat domain 62 like", "gene_name": "Ankrd62l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRVAGLSSKKSRWLLQSLLDQQRHSLGTGFESANILLSPKYHLKDKDLRKIHKAARDGDAARVQQLLLGKHCVNDKDKKKRTALHIACAYGHPKVVMALVEGKCEVNATDSEECTSLVKAVQCQEEECATILLENNADPNIVDAQGNSALHYAVYYKNTSLAAKLLDHEVNIEATNKDGFTPFLLAVSENKLKIAKFLLMKNASIHAADNQKRTALMHAVSHDSTNLVRFVLEQGVDLFVKDAFGLTAIDYAADFKYNSNMEILLEYKAKRYEESERANLVEKSSEEDSSRRKDQQSQELENMEKEELTEPGNGTEEQEPDGGVTSVEEPRRLDDRGDDQPQEAVTAPRTREKEQELPFTDMCTVVTGKEDEDESSWDSESVSENLPLIRIGVDGLLLVNGQAVENPEKYLHWLHNRKGEESVPNETKGVGDLQAFTPAEPGLELTSEEKHEELSRNEDCQPQVEEERTQEWSGWGAPEALCAAALDHGDIGSPLTRENGHPRARQSPSVDSEEQDGGSGLNIKEEKTRDHEEWSGDFLMDRTSKESEPAAGDLLQVKDSWSLNDTDPNKGSPAKRKSKEKHKVRGEMNAMEDADDFTPLSESCSDNKAELCCNTHQAETETESCELLTRQTGNMEGGVAGEVLKTEPARSREALKETEETGEGARVKMQLPGKDELYSEDAERQQYDMALSALHLKTKQTVRQLQETQDRQREVVRSSQRMQDHLQKLQAGCSEAEAMVQEQGKKTAELQKLHAGMIHELKEKWETIASKYLPLNIQLKYLEQELLSIKIAQKQYEKLHEDQRTLQRDAVDLQHQVQENMAKLDDEKQAMALRDSNNDSLMSQVELRIKNLESNLQKLQAEKESNERNVEKYLQRYIRERELSKTLSHTLHRTNSKLSRVRTDILLVTERNRTVQNTLTTRPVPKSPGVTEHSAYVNRNPNFIASRNLEAAMSSPQPSPELMRRRLLKKQKNMVKNITEEVDKAAAELESWSLEAYPSGSK", "length": 1003 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G430-1", "protein_name": "Large ribosomal subunit protein eL24", "gene_name": "LOC689816", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLETCRNLSAIGYIWEDNSTEEYCKSSRRHGRPTSVTMKVNLCSFSGYKIYSGHERLYARTDGKFSSFLMPNVSPHSFPKGTLGKLTGLSSTEENTRKDSRKKFKRKEPTLQKFQRAITGASLADIMAKRNQKPEVRKAQQEQAIRDAKEAKKAKQASKKTAMAAAKAPTKAAPKQKIVKPVKVSAPRVGGKR", "length": 193 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G808-1", "protein_name": "Paired immunoglobulin-like type 2 receptor beta", "gene_name": "Pilrb2l7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARILLLLLSAACLHTGNSAGYPKKYDYGVDQPAVLSGVQSGSIEIPFSFYFPWELAKDPQMRIAWRWKVFHGEFIYNSTQPFIHEHFKGRLIMNWTQGQTSGVLRILNLKENDQATYFSRVFLRTTEGMKSWQSIPGTQLIIHALITTPGSPSIIPSAVPTTGLEDTRGQRTPSLLNLGAMVGMVVSKVVVIIPLYGWVIFLWWKQRTQFRRDLVSEHPWKNFVPILPAESSSFL", "length": 236 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GB91-1", "protein_name": "Olfactory receptor", "gene_name": "Or4c117b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TNRYYFNIFMIIMQNQSFVTEFILLGLSQNPNVENILCVVFLFIYLATIGGNMIIVVTIIYSPALLGSPMYFFLIFLSLLDACTSSTVTPKMIVDFFYERKTISFECCMTQLFAIHFFTGIEVIILSAMAYDRYVAICKPLHYSSIMTQRLCGILVIVSWAGGFLHSIIQIIFTLQLPFCGPNVIDHYLCDLFPLLKLACTEPHIFVILVFSNSGSISIIIFSILLVSYGIILFSLRAHSSEGRRKALSTCGSHITVVLLFFVPCFLIYARPTSAFSSEKNAFVFATIITPLLNPMVYTFRNKEMKNAIRKMWKRLIMVSCNY", "length": 323 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GF85-1", "protein_name": "Ceramide-1-phosphate transfer protein", "gene_name": "ENSRNOG00000064148", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "HFFLEYLNNLKIMLIFLSPPTGGWASDHHSPTTGTHLRFLNSLGAAFSFISKEVVSKLQIMEHPRSSPQSEHCSSLQSMAAYEVSNKLLDLARRSGPLHSNSGCRTVLCLHRALHWLQLFLEGLRTSSEDARTSTLCTEAYSAMLCAYHSWIRQAVTVAFCALPSGKVFLEMLGEALPFMEQMCDISQFYVEHFLLDLP", "length": 199 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GFV7-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f21c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLTMYLATVLGNLLIILAISTDARLHTPMYFFIMILSFTDVCFSSTTVPKVLANYMLRSQTISFSGCLTHLYFLCVFADMDNFLLAVMAYDRFVAICHPLHYTTKMTNKFCVLLIVGSWVLTNLNALLHTLLMAQLSFCGDNIIPHFFCDATPLLKLSCSDTHLNDLMILTEGTMIVVTPFFCILISYIHITCAVLRVSSPRGGWKAFSTCVSHLAVVCLFYGTIISLYFNPSSSHFAGKDMAGAIMYTVVTPMLNPFIYSLRNRNMKGVLRKVLILRFPSKQ", "length": 313 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GGC1-1", "protein_name": "Histocompatibility 60b like 1", "gene_name": "H60bl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKGATSKCNHSLTLSLLVLLNSLGTMQVDGTDSLSCNFTVQYKVSLGQCSVNGMTVLCFDDVRQNSPVCKTEKKGNATKLCNDLNQCLSYSFYEMMKLESGLFESKGNHTLRVTVQSQYNQGEFMDGCWAFMIDRQYPFYFYPKNMTWRENQPNAIKTMSQWENNRELFQSLKFLSTGDFSLCLKKLLTDSRELTRSTIKAPDTTQPTSTTQSPSTGNSTPAMSSNQSPSTGNSTQPTSTTDYLIVFEFTAIFLALIVVSMEKKKVLPAAPLPLQYELQSPSPAVLEES", "length": 290 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GIM2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x11c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADLFNVTEFIFLGLSPNKEVQRVCFVLFLLLYMAIVLGNLLMVVTVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLILDLLAEMKSISVWGCMTQLFFLHYFGGIEIFLLTVMAYDRYVAICKPLHYTSIMNRKVCIVLVGTAWTGGFVHSFAQIVLIFPLPFCGPNTIDHYFCDVLPLLKLACSDTFLIGLLIVANAGTLSVIIFVVLLASYVVILFHLRTLSAEGRRKALSTCGSHVTVVILFFGPCVFIYSRRSDTLPVDKMIAVFYTVITPLLNPLIYSLRSAEVKKAMKNLWFRTMKADEK", "length": 309 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJN1-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein A1", "gene_name": "Hnrnpa1-ps20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "LSQSPPRNRTEQLWKLFIDGLSFETTDESLRSHFERWGTLTDCVVMRDPNTKRPRGFGFVTYTTVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTVKKIFVGSIKEDTEEHHLREYFEQYGKIEVIEIMTDRGSGQKRGFVFVTFDDHDSVDKIVIQKYHTVNGHNCEVRKALSKQEMASASSSQRGRNGSGNFGGRGGGFGGNDNFGRGGNFSGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGSRSSGSYGGGGQYFANPRNQGGYGGSSSSSSYGSGRRF", "length": 319 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GJR0-1", "protein_name": "Aspartate aminotransferase", "gene_name": "Got2-ps6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLHSRMATTFHPGLAAAASARASSWWTHVEMGPPDPILGVAEAFKRDTNSKKMNLGVCAYRDDNGKPYMIPSIRRQRPRLLEKIWTKNAYPSGDWLVFVRLLQRSEPVFCKDILSLAKMSFYPNHPGETTRPSSGMPACSYKVIDTMTHKTCGFDFSGALEDISRIPEQSVLLLHACAHNPMGVDPRPEKWKEMVSVVKKKSLFAFFDMAYQGFASGDGDKDAWAVQHFIEQGINVCLCQSYAKNMGLYGERVGSFTVVCKDEEEAKRVESQLKILIRPLYSSPPLNGARIAATILTSPDLRKQWLQEVKGMADRIISKRTQLISNLKKEGLFHNWQHITDQIGMFFYMIKDGRISVAGVTSGNVCYLTHAIHQVTK", "length": 379 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL73-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC134481331", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "TALLVSLPEQNLAMARILLLFLSAACLHTGNSSGYRRVNDFGVNQPAVLSGVQSGSIEIPFSFYFPWELANDRSMSIAWIWKYFHGEVIYNSTQPFLHEHFKGRLIMNWTQGQTSGVLRILNLKENDQARYFSRVFLRTTEGMKSWQSIPGTQLIIHALNTTMGSPSIIPSAVPTAGLEDKRGQRNPSLLNLGVMVGMVLAKVVVIIPLYGWMIFLWWKQR", "length": 221 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLF3-1", "protein_name": "Heat shock protein 90 alpha family class B member 1, pseudogene 13", "gene_name": "Hsp90ab1-ps13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEEVHHGEEEVETFAFQAEIAQLMSLIINTFYSNKEIFLWELISNASDALDKIRYESQTDPSKLDSGKELKIDIIPNPQERMLTLVDTGIGMTKADLINNLGTIAKSEDQTEYLEERRVKEVVEKHLQFIGYPITLYLEKEREKEISADEAEEEKREKEEEDKEDEEKPKIEDVGSDEEDESSKDKKKKTKTIKEKSIDQEELNKTKPIWTRNPDDITQEEYGEFYKSLTNAWEDHLAMTSLSGYVSRMKETQKPIYYISGESKEQVANSAFVERVWKRGFEVVNMTEPIDDYCVQQLKEFNGKSLVSVTKEGLELPEDEEEKKKMEESQTKFENLCKLMKEILDKKVEKVTIPSRLVSSPCCIVTSTCGWTANMERIMKARALRDNSTMEYVMAKKHLDINPDHPMVETLRQKAEADTNDKAVKDLVVLLFETALLSSGFSLEDPQTHSNCIYCMIKLGLGIDEDEVTAEELSAAVREEIPPWRVMRMPLAWKKWIKGSWEAPALCIVSLGLPQQP", "length": 518 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GM54-1", "protein_name": "MAGE domain-containing protein", "gene_name": "Mageb11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPHDQKSKLHSRENSYQAGGGAQAYGDAEEIAEAAAEAAEESSAKSQSQPGAEYSRNHRAPPKAKPSAKLILSSSSSESDESSHEESEPSVQKDRPFLHQDLIERRVAILLQYLLHNYNLKQLTTKEEMLKVITKKYEKDFPEILRKASEKLEDAFAVEVREVSSSQPSYDLISKLKLPNNGRIRAGKGLPKTGFLMSILGIIFIQGNSASEEDIWKILKKKRIYPGKKHRVFGEPRKLMTQYLVKLKYLEYRQVAHSDPPRYEFLWGPQAHAETSKMKVLEYLAKINKTTPHAISALYQEALKDEKERAEVRDEDNTDTTDQSTEGSPEKSPTASTTPVDT", "length": 342 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8J8YII4-1", "protein_name": "Coiled-coil domain containing 188", "gene_name": "Ccdc188", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGPEPLGPCGHSHTQHPPAPVSNNHGGCLNQPCQGFVRWPCLVPLQSTQSLESSRPFPAPGTGSGGPRMRGEAPGMFLSSEGEIPRQRAREPAGARQEEVEVEWDWPLHPGHEQGPPRQTAPPTSGPRPCPCPTLPPRGRATASSRQAPTQLQGGTLESAQQSFLQLEQENHSLKRQNQDLREQLGALLGPGQQFLPLCSEHSSCTALAWVSGNTRSRTHAAAPPAVHSLGPDPGALPQSPESARTRLLEDRAPVQLLRQQELCPGKESFVRQSQSELQQIRLSFERKKMAITEVWDGVAEVHMALNNQATGLLNLKKDIRGVLEQMEDIQLEILGERAQCRTQARKQQQMMEAAGLEAAAGCSAGLHSGLRVRGGPHTLRGAGATPAEPSQRLEAQGLTGSLLTPGGGRLPAFLEQKPSGPSKEARWLVLPQGLRGLTGPCLQHCGTWPLPEAAEKGGGRASPEGWACSWIYSHDTLCM", "length": 481 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVG7-1", "protein_name": "5-hydroxytryptamine receptor 7", "gene_name": "htr7a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLGDTNRTIIAKSHGETMKSLMAEERARETGASVETFNGIMISEVLVPRLFKIAHESGEVAVAAGSGSMDMKPSSSPILLEMMEVANGTRCAEQILSYGEVEKVLIGGVLTMLTLITICGNMLVVISVCFVKKLRQPSNYLIVSLALADLSVALAVMPFVSITDLIGGRWIFGKFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGWCMAKMVLSVWLLSASITLPPLFGWAQNVNDDRVCLISQDFGYTIYSTAVAFYIPMTVMLVMYYRIFRAAKLSAAKHTITGFPRVEQEEVEEDEVEEDGGDGAEEPTGVDCVTVAIKLQREVEECARLPRILRGVGRRCSDRRSISIFKREQKAAATLGIVVGAFTICWLPFFLLSTARPFICGTECSCIPLWVERTLLWLGYANSLINPFIYAFFNRDLRTTYRSLLSCRYRNINRRLSAAGMHEALRLVERPEVVVSG", "length": 479 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QGZ8-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "pimr118", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLFTVLGVIALFLRERDTNNTEEEVQNDVPPVRNSDGQEIDDWCKEPSLLEPVSVHSEEPSLEEPVSAHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLKEPVSVHSEEPSLVEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPVSVHSEEPSLEEPSLDLSFFSAESSWSEDLSSSFLTVESSWSDDLSSGFLTAESGCGDDEPLFVDSAEPEKLKEDKETQIIEINSHCYAIEAQLGEGGCGAVFSATRLEDGLQVAVKLSDFEEEKRFISVDGFEDPLPLEIALHFLANKGPKVKEIIELLDWKVEADRYFMVLEQPIPCMSLHEFLLDCEGIIPENKLRTIMYQTTVAAQTCCQRGVLHRDIKLENLLINPDTLEVKLIDFGCGDLLTEDSFQYFRGTREYFPPEFSSTGRYHGEPATVWSLGVVLFLLVFYRFPEQSDLPRMNNRRLRIKGLSRDCCDFFHGCLQLDPKDRLELQNLSSHKWIRTRTRRNDENCPNLTDGSSHSNHPITSN", "length": 567 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0WZU8-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6B2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMVVNLILGWWLVAVSRAQKLPRPSLSLHPSQGASLGDNVTLRCHLPQPAAWVRLYRYQNPTYIEQKDNVQDMAEFSLTSIKQEDAVIYQCQYQGLAPAGTSQKSDPMELLVTDHRYPPPGISLSPKEHVEMGSNITIQCWNKDYGASFLLHKGGHSAPIQHQEPDYWGTATFTLFGVTPADSGTYRCSYRIGGCCLLFSPLGDNVTLEVIPRPAPPGVNGGPSRNLVAAVAGGCAAAIVIITVSFLLVALRRQMQRAERPGATPRSPEAVQFQVSPGDSEGLTYAQLQAVTPSTHPPTSSTTPEPPIIYAEVGTRGPR", "length": 321 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEA0-1", "protein_name": "C-type lectin like 8, MHCY region", "gene_name": "YLEC8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 276 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XED4-1", "protein_name": "C-type lectin like 18, MHCY region", "gene_name": "YLEC50", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTSSDPQLPEEDVQILLLESNTSTPAMGEGDQQETFSEHQAAPEPLGQSGGHQWGSWCHGMGRRRSCVQLIAVHAALGALILMLVVLVISTVCRRAPIPPFSAFGHACPNAWVGFQGKCYYLSKEENDWNSSREHCSAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKAHPQ", "length": 276 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XEJ6-1", "protein_name": "Sulfotransferase", "gene_name": "LOC769841", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVCRAAAPNSHPSTMPVHYVTYKGIKFPPAYNSVHSLSFAHNEFLVRDDDVFNITYPKSGTVWMTEILSLIRSHGHPSWNQTVLNSDRMPWFSTRLGLEAALSYPSPRLLTCHLPRHIFPKSFSHSTAKVIYTLRDPRDVVVSYFYFCKMCNSYEDPVSFEQFLRDFLSGELPHGSWFEHVRGWMQMKDRENFFFITYEELKQDLQGSVRRLCHFLGQNLDDDAISSVVQNASFMAMRQNPMCSSILLPADIMDQTKGQFLRKGICGDWKNHFTVAQTETFNRIYLEKMRGLNVAFPWDRDQDPDLTEQ", "length": 309 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGU1-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "YLEC62", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQSVQIPILKHKVSTPAEGERLNHFSEHKAAPEPTAHQRRRIPTGSDPQLPEEDVHISVLESNTSTPAMGEGDQQETFLEHKAVTEPLGQSGEKPQWGSRCHGTGRRRSRVQLIAVHAAVGALILMLVVLVISTVCRRASIPPFSAFGHACPNAWVGFQGKCYYFSKEENDWNSSREHCNAHGASLATIGSAEEMDFMMRFQGPANCWIGLHREEEDAQWTWSDGTAFTNWFELRGGGRCAYLNGDRISSSLCHLHKHWVCSRADHYVLWKQKVHPQ", "length": 277 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XGW1-1", "protein_name": "NHL repeat-containing protein 3", "gene_name": "NHLRC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAPAVLWRLQRLSAAERLEARLSGAVRKEPGRGEARQSEKKPHSPHCPLRCSYACPGRTPMTSESGRKALSHLGRQQQCLNKMAELRARLEAFPAPECLFKTLNPFMGFLRLFFAPQPLGGEQALFRAAQCAEASPRIPAPQAWAGRSRGCHGNAARPASMGRKQAVGPRLVMAGALLTLLGLLWGSQMLKAFDYFSSWKGDGEQQMYKLDISWPKIPEYFSGQTFCVAVDSLHGLVYVGQRGDDIPKVLVFSVEGYFLYSWNDTVEMPHGIFVLNTATDSSVWITDVGSGKYGHTVKQYSPSGKLLQVLGTPGNAGSSLNPLQFDQPAEIFVEESGEMYIVDGDGGMNNRLLKLSQDYKEIWLSGENGTGIGQFKIPHSVTVDPFGRVWVADRDNRRIQVFDKVTGEWLGAWSSCFLEDGPYSVRFTGNYKYLIVAHLNINRLAILAAPPVGEIGDCAIVSTIQLADETKPHLVDVDVKSGAIYIAEIGAQQVQRFVPLS", "length": 502 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPN1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR2A13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPMAVALILGWWLVAASRAQQLPRPSLSLHPSQGVSLGDNVTLRCHLPRPAAWVWLYLEGRWSYAKYIDKKQDTTEFSFLSASHDQAGTYLCQYQVSESEDVSVTSDPVKLVLTDRSFPPPHISLHPEERVGTGTNVTICCWNKDYGATFLLHKDGRSDPIQRLVPDDVGAVSFTLFGVTPADSGTYRCSYHPKNYPFLSSPLGDSVTLEVTPTPAPPGAELVSRGNLVVAVVRGCAAALIFGLGVFFVIDARSLWIRRDESLGGEGI", "length": 269 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XPP6-1", "protein_name": "SUN domain-containing protein", "gene_name": "LOC776146", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEQQGHGERGNWQTKVWKTVALVLVTVAVASFGVYCVGGLVEGIKTTAGVTARLVRRDGEIVSLDEELAKVQRQLHVLQWRARDITERALHEALRRTELPGFTGEAVQKIIHQVLEKLEESPFQMTNYASKTSGAAIVRSKTSPSWIGSGRVFWQSLPLVAYMRPPEVILEPDNHPGNCWPFPGSQGHVFIKLPVAVFPTAVTINHGVPAAAYHADSISSAPKDFAVYGLQEEDDETGTLLGEFIFMPGQAPGQTFQLKNEHSAFIKYVRLQVLSNWGHPEYTCVYQFRLHGDPAPDGDARGKLSA", "length": 306 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XQE0-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "CHIR6A8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEPMAVNLILGWWLVAGSRAQQLPRPSLSLHPSRGVSLGNLVTLRCHLPRLAAWVWLYRGGGWSYKKGKKKEQDAAEFSFASTLREHAGRYRCQYRVYESAEVSVESDPVELVLTDVRYPPSSISLQPEQHVGTGTSVTIHCWNKDYGATFFLHKDGSSDPLQRQDSSGGGTATFTLFGVTPADSGTYRCSYRHWRYAFMSSPLGDSVMLEVTPTPAPPGAELVSRGNLVVAVVRGCAAVLIFALGVFFVIDARSLWIGRDESLGGKGI", "length": 269 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0XTD2-1", "protein_name": "Coiled-coil domain containing 97", "gene_name": "CCDC97", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKEDPKEAEGPTASKWIPIASNGNPTASKWIPIASNGDPTAPKWVPISSNGDPNWVPISSNRDPMASKWIPVSSDRDPTVTKENPPSSNETPAAEWDPKVPPEGRPVEEGDPKASPTEDPPAEPDPKASNCAPLSSHWAPEAAVWDPTSPHRDPTAEPQCSASPEQHRAAQRDPASPMEEDRYPATHGVRPATRADPAPYGDHPEAEEDPLPAAVEAMLAAVAASPVRVRSQQQGDPELTAAERRRDLRALFLRKPLVFLERFHGALQAEHLPCFAHLPPRYEVAFYCRQVRARRQQNPQTGLSRWPRRPGARTRLRNRRYAALRQLIAGGEYFSEEEMRAREPLLYEHYIGQYRDAETPPGTPPCPPHPGTPPGTTWAAALLRSVEEAAVQQRLQRQRLREGDSGEEDEDEDEAEEPHIPDAGELEVLREEFRSRMYQRFLDGEDRDFDYSQVDENPDMDNLDIESRDAEERYFDEEEPSAAPQLE", "length": 487 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Y889-1", "protein_name": "Transmembrane protein 65", "gene_name": "TMEM65", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWLGRAVLLLGRPGGPAAPSSSSRLCSLRGPPRCCCRRRLSSLRGGADGLLPARGAPPGRALGTHPKKEPMEALNTAQGARDFIYSLHSTERSCLLRELHRFESIAIAQDPIAARASCQQYGETWAHQEPSGACSSVHSQAYHQKEAVPSSNCPSTKYDRTHYLWPPLMAEAAGKPGRCPHCCAEGWSSEKLEVAPPSPGQLRHVFFHNALPFVGFGFLDNAIMIAAGTQIELSIGVVLGISTMAAAALGNLVSDLAGLGLAGYVEALASRLGLSIPDLTPKQADMWQTRLSAHLGKAIGVTVGCILGMFPLLFFGDEEEKLEEKN", "length": 328 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YA34-1", "protein_name": "SWIM-type domain-containing protein", "gene_name": "LOC100859602", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERGQLPPYAKRLCCRPGYGSGCRLGQQAGDTGPGSGTFCAGPSSAAAAAAAAAAATAASLVLLPLGKTQSPESLLDIAARKVAEKWPFQRVEEQFERIPEPVQRRIVYWSFPRSEREICMYSSFDTGAEGFTAPGSAAGNTASGGAVDAVADENRLPFRRGMALLDGGCVDNVLQVGFHLSGTVTEPAMQSEPETVFNVAISFDRCKITSVTCSCGNKDIFYCAHVVALSLYRIRKPDQVKLHLPISETLFQMNRDQLQKFVQYLITVHHTEVLPTAQKLADEILSQNSEISQVHGAPDPTAGASIDDENCWHLDEEQVQEQVKLFLSQGGYHGSGKQLNLLFAKVREMLKMRDSNGARMLTLITDQFMADPRLLLWRQQGTAMTDKYRQLWDELGALWMCIVLNPHCKLEQKTSWLKQLKKWNCVDVCPWEDGNHGNELPNLTNALPQGANANQDSSNRPHRTVFTRAIEACDLHWQDSHLLHIISSDLYTNYCYHDDTESSLFDSHGWPLWHEHVPTACARVDALRSHGYSREALRLAIAIVNTLRRQQQKQLEMFQARKKELLYRGITSITNLEGWVGHPLDPIGTLFSSLMEACRVDDDNFHGFSDFMENTSQHKSLEYQHLPAHKFLEEGESYLMLAVEVALIGLGQQRIMPDGLYAQEKVCRNEEQLISKLQEIELDDTLVKIFRKQAVFLLEAGPYSGLGEVIHRESVPMHTFAKYLFTSLLPHDAELAYKITLRAMRLLVLESTAPSGDMSHPHHIASIVPNRYPRWFNLSHIESQQCELASTMLSAAKGDVQRLETVLQSIQKNIHSSSHIFKLAQDAFKIATLTDSLPDITLLKVSLELGLQVMRMTLSTLNWRRREMVRWLVTCATELGVHALDSIMQNWFTLFTPTEATSIVATTVMSNSTIVRLHLDCLQQEKLAGSARTLALQCAMKDPQNCALSALTLCEKDHIAFETAYQIVLDAATTGMSYSQLFTIARYMEHRGYPMRAYKLATLAMTHLNLSYNQDTHPAINDVLWACALSHSLGKNELAAIIPLVVKSVKCATVLSDILRRCTLTTPGMVGLQGRRNSVKLMSLDKAPLRQLLDATIGAYINTTHSRLTHISPRHYGEFIEFLSKARETFLMSHDGQIQFTQFINNLKQIYKGKKKLMMLVRERFG", "length": 1168 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0YDY5-1", "protein_name": "SKA complex subunit 1", "gene_name": "SKA1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MEAEGLEALSRHLAAKIGLIKRLLQLRGLGRREMLAEVGMEVAVLHGLLGRMEEEVNQRRQLAAALQEMRKRAEKEKWEAERLQLVKKAAKEAPLVNDAPLISDEEFESVPGYMRGRLTLAQTNAALRALHAAAASKYRLLRHPPKSLPSSSRALCHRFREEETKETQGLTFVVEADLKEFTQLKVDRTFHRIVGVLRHCRRLREVRGARLVRYVLP", "length": 217 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0Z0M2-1", "protein_name": "Tumor necrosis factor ligand superfamily member 10", "gene_name": "TNFSF10", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLPAGGPSPAHTCGAVLVAAVLLQSVCVAVTYIYFTNELKQFANADLVHSCERGHPLSPPPPPDVPQTAVTRPTKAEGGAAPVGASCSIGQSRRAQSDLRQRAANAASPQHGPPCAARSRARCSCPRCTAGPRVCRRTQQKLWDTYSRSGTACLTGEELGDLIQNLDVVESKDRVADPCWQVKWHLGKLIKKMMSRILQENMSAINGDRTQALPRRDEPPQGPTLRIAAHLTGSSKRSSASPHIDYLSYRGIGHKIHSWESSRRGHSFLYNVELWNGELVVPQTGFYYIYSQTYFRFRENEDEDSGLLERIKNPKQLVQYIYKLTNYPDPILLMKSARTSCWSKKAEYGLYSIYQGGVFQLKREDRIFVSVSNSDIVDMDKEASFFGAFMIS", "length": 392 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZCD9-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418390", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMSALLFTLLHYWKIWFCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEREEQQEQVEEEEQLERVEELEQEDQVEHVEQEEQEEREDQGEQVQQEEQVEEVEQEDEEEEYFHHSALTRYIARRAWEKMQGKATKCVLVEELMSDLLQTYTFVCSNSFYPVLQPAIGVGSAFEGWSPCEEDIVYRLLVPIKAPHGHVFHPELGEEGEVLARNSRIRVELVCMCTREQQLGDVLCFLHHSEEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRTWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAVFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKVLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRVLRDFKELKDRLFRLLLFGR", "length": 542 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZD85-1", "protein_name": "Mab-21-like HhH/H2TH-like domain-containing protein", "gene_name": "LOC124418382", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALVLVLALLVRALIVSGSDHAVMLERVQQHEKEQRNGEQSWVDMPALLFTLLHYWKIWLCTGLFVFLFWNMWRSLKRKQHEEGGQQEQQEREEQVEEVEPEEQQEQVEQEEQLERVEELERVDQVEHVEQEEREDQGEQVQQEEQVEEVEREDEEDEYFYHSALTRYIARRAWEKMQGRATKCVLVEELMRDLLQTFTFVCPNSFYPVLQPAIGVGSAFEGWSPCEEDIVYHLLVPIKAPHGHVFHPELGEEGDMLARNSRIRVELVCMCTREQQLGDVLCFLHHSQEELSQNQQPSLLQTLCTGSYLDVQKTAAWFNKQVPRIWRLTHRAHRYGLKVLPSSRSCKLQVTDTSSGEKVHVELLFGVQQGNLDIFLSSQNAEAIFTPSTTWPQSCAVAERKYFEYVARTAGPNSCHLVCLRLFAHILVGMGFSTYAIKTLLLHLLAIIPLEDWRRRHFLSRLENLLQYLQYCLNDKLLNHFLLGNATMPDEVVLPQAFQTASPLNLFQHLEQDPDAHSRALRDFKELKDRLFRLLLFGR", "length": 539 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZE07-1", "protein_name": "LIM domain only 1", "gene_name": "LIMO1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQRDSNPMGWYGSHPVTAAWEAEARTTSLGQPGVRAAELP", "length": 158 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZGC1-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "LOC124416945", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVAGSPALLLLLSLGLCFTGAQGQGNTMAVSFLNRSMKHPKEGQRLGLECHTYKTSWGVSWIRLDKDGNLHFIVYISKFSSTTFPGNKGASSQFEVSKQGSSYRLTVKNFRAQDQGIYFCIANINQVLHFSSGQRAFFPVTTTTAAPTTLRAVTLTATTQSSQVTMKDISQHSPDPGRSKENMPNFCCKLVMWVNLACACLLLLTAITITTTHCQRPSSP", "length": 220 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V0ZPB4-1", "protein_name": "trypsin", "gene_name": "LOC107049069", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKFLVLVAFVGVAVAFPIRDEDDDKIVGGYSCARSAAPYQVSLNSGCHFCGGSLISSQWVLSAAHCYKSSIQVKLGEYNLAAQDGSEQTISSSKVIRHSGYNANTLNNDTMLIKLSKAATLNSYVNTVPLPTSCVTAGTTCLISGWGNTLSSGSLYPDVLQCLNAPVLSSSQCSSAYPGRITSNMICIGYLNGGKDSCQGDSGGPVVCNGQLQGIVSWGFGCAQKGYPGVYTKVCNYVSWIKTTMSSN", "length": 248 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A1Z3-1", "protein_name": "Bridging integrator 2", "gene_name": "BIN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSLYHPNAIPVPFPSHPCTTLMSSLTHHIIPVPSSCLPNVIPIPYHPHVISTLSLLHPHFIPMAFLNLPHAIPVPPLIHSCAVPMSYHPFPISFSFPSPSHPSIAPMQSPSYPYPTPVPPPFHLLPIPIPTPVPPPCHSCSIPIQPRCRLHAILVPFPPHCHPHPVPAPSPPHPSAIPMPSHFHPHPIPVPPHTISIPSPPQCHLHAIPVPSPTHPHPIPSHPRFPHPLWAQGHPHPRGSNLSPPIPPPPPNTFALQNEGNKLYKDLKAFVGAVKVMHESSRKVAETLQEIYSTEWDGHVELKAIADSNDLLWDDYEAKLGDQALRLMENYLAQFGDIKERIAKRGRKLVDYDSARHHLEALQNAKKKDEAKIAKAEEEFNRAQAVFEELNRELREELPVLYGSRIACYVTIFQNISNLRDIFYKEMSKLNRDLYEVMGKLDKQHSSKVFIIKGVPSKRRSLLISAPVSPPAAYPCPGKAPNWDPSSGAEQTPTSPRVGSDATEDVPNGLAAPGPAEPGAPMPGPPPASPTSVRSASESESECSEESREIDLSPKEMEVSVGSGCPEYPKTEGAAKGEVEGIAASMASMIVSEAIAAATGAAPGDSDGVGGGDSTDSEISPAEGAWGGPSPGGSEERVEGTDVSPEVGSDAGPCEHGTPEPPQQDVSCDPPQDPSESLTPL", "length": 682 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1A7J1-1", "protein_name": "Mitochondrial transcription termination factor 4", "gene_name": "MTERF4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGRLLGLLRARAPRAVLPAPGPASRHRCGTAGPEEGEAAELLAMGFSQAQARRLRLLRPGLEPQRRAEAAAQLLLLGLSAEAALGLLERSPGLLRMETARLKERAEYLRRLGLEGERGGPLPRGVHAAPAEDGGGGAAAAGAVSVHGRAADRAAAELPRGAAGGAGPRAAPLPGAGRRAGRSGGVAGAARPALSSARLHAQYAYFRMGVRQKEMVKARLFRTPFAELRNRHVFLERRGLYRTPHKGQSQSGNPALRDVLRPTEGDFVAGVARASPDEYEVFKRLLAREEEEMEEEEEEDEEEEEEEEGSAALHAEGGDRDWHSSEPSPIAPCPPAPQ", "length": 338 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AKD9-1", "protein_name": "Borealin", "gene_name": "LOC121107214", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAPARRKAAAGARGRKLSAFLKDFDREVRSRVEQLRTNGERLVKEMENLYDVELLRLPAALREMNWLEFFAKGGSQKVVEEAVTADLGITEINKLTAELIQTPLKIVTKEKSKQGIEATEEAAEVPLLPPAKKAKHDSQLLLEQAAASTNPRNGKVRTSTKKAPVSRSRRAPSARVKRVSKRSSKSSFITPATGRNLDLCARGGASIVTPRFDSRVFKTPGLRTPAVNERVYTISANGSPLADGNDVFITVPVGGGESIRLTASDLTKKNLLHLNPEARGIMKKLSVRLAQACSSAKTHR", "length": 300 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8V1AMC7-1", "protein_name": "ODF3A protein", "gene_name": "LOC121107218", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPASMDGAWVGTWRPHRPRGLISAQFPSPGPQYSIPGTTGYVGHSPTKARAPAYTFRGTKPPAAGSCGPGPCYFVEPAITRNGKYVAPGAQLRGRPVTKTTVTPGPSDYRTEAANRHVFKCPPVQSMAFRREPLRTDHPPGPGTYTLPRLMGPNTVYTSASPCYSVRGRSQRGRFDEDLAKTPGPAALPKVPVDAYKTRAPAYTMAARPKAGEGKAAKPGPADYSVGRVTLIKPQAPASTFGIRHSLYTTPLIVE", "length": 255 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8W4F7J1-1", "protein_name": "40S ribosomal protein S26", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQPIHCTNCARCMPKDKAIEKFIIRNIVEAAAVGVISEVSVFAAYVLPKLYAKRHYCESCAIHSKVIRNRSREAQKVRTPPPRFRPTGAALRPPPKCM", "length": 98 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F8K9-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258234", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTVTTFILLGLTDEPQLKTLVFIFLFLTYMLSVTGNIISLTSTDSHLKTAMYFFLQNFSFLEIAFTSACIPKYLYNIATGDKTITYNSCATQLFFTDLFAVTEFFLLATMSYDRYVAICKPLHYVTIVNHTVCRRLIFGSWLAGLLIIIPPLSLGLKLEFCDSNVIDHFVCDAAPLLKISCSETWLIEQMVIVCAVLTFIMTLMCVVLSYVHILKTILQFPSAQQRKKAFSTCSSHMIMVSISYGSCIFIYVKPSPKDSLAVNKGVTILTTSIAPMLNPFIYTLRNKQVKQAFNDAIKRIALFSKN", "length": 309 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4F9E2-1", "protein_name": "UPAR/Ly6 domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "RLEFSSLSPAEVPLVAAAGGRGAFDMRCHECDTKNTFACDHIVTCPRGIRRCLTLSIRLSSREIYVYKGCTRNCTFIYADEQPPPGERKPPRSNSLYFVQCCNAITCNRGGPINLEKDITPPLILEEELGGTVRLGEATLFLSVASVLVSHALT", "length": 154 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBC5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLTHSFSFFSSSSSSSTYSSSYPLLPLLLQPQNQFRIWALKDYGQRNSTSLHDFILLGVVATFYLITLVGNTAIILASLLDSHLHTPMYFFLRNLSFLDLCFTTSIVPQMLLYVYMWLGSIECLLLAVMSYDRFTAICKPLHYLVIMNPHLCLKMIIMVWSISLANSVVLCTLTLNLPRCGNNLLDHFLCELPAMLKIACIDTTAVELSVFALGIAIVLTPLILILISYGYIAKAVLRMKSTAGQRKAINTCGSHLTVVSIFYGAIIYLYLQPGNSASKDQGKFLTLFYTIITPSLNPLIYTLRNKDMKEALKKLMRVDHKSTKSKRTWKS", "length": 331 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FBS2-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258626", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRNHTAITTFILLGLTEDPQLQLLLFLFLFLTYILSVAGNLTIITLTLLDPHLKTPMYFFLQNFSLLEISFTTACIPRFLYSISTGDRTITYNTCFTQLFLTDLFVITEFFLLATMAYDRYVAICKPLHYMTIMSNKLCKTMVVCCWLAALLIILPPFSLCFHLEFCDSNLIDHFACDASPLLKISCSDTWLIEQMVIACAVLTFIITLVGVVLSYIYIIRTILKFPSAQQRKKAFSTCSSHMIVVSITYGSCIFIYINPSAKEEVNLNKSVSLLISPISPVLNPFIYTLRNKQVKQALHDSLKKTAFLLRK", "length": 312 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FCJ2-1", "protein_name": "Histone H2A", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSRKRNLPQCNPPKKQALSRSSRAELQFPVSRVDRYLREGRYAQRLSSHTPVFLAGVLEYLTANILELAAGEAHSSRKMRIAPEHVQRARSHNETLSSLFQASSVSRGAEEEAEEPLPEAGR", "length": 122 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FD42-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFIILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLNCCITQLFFIHSIFVFESGLLLVMAFDRYVAICYPLRYTTILTHPLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLLLDILLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVCIIILFYGPGIFTALTQRFGRHIPAHIHILLANVCILVPPMLNPIIYGIKTKAIQEQVALILFPKYR", "length": 314 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FH98-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "VCHYGNYYSGLSCSCGYGCGYSRCGCNCDYDKCGYRCGYGGYVYGCCHLSCCGRYRPYGFY", "length": 61 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FHY5-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "DTGSCGAIVLTQTPLSLSVSPGEPASISCRSSQSLEEYGKNWLSWYQQKPGQSPRLLIYQATNRASWVPERFSGSGSGTDFTLKISRVEAEDAGVYYCQQYKEFPPTVIQPLTQTPLLGAQLHTWLCVVWGAEGQKL", "length": 137 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FIZ4-1", "protein_name": "Envelope glycoprotein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRPTLSRRHLPTRGGEPKRLRIPLSFASITWFLTLTITPQASSKRLVDSLTSPKPLSLTWLLTDSSTGITINSTQREAPLGTWWPELHVCLRLVIPGLNTMSTPPDILRAYGFYVCPGPPNNEEYCGNPRDFFCKKWSCVTSNDGYWKWPTSRQDRVTFSFVNSYTSYNQFNYGHGRWKDWQRQTQNRQISCSPSDLDYLKISFTEKGKRENIQKWINGMSWGVVYYRGSWGGEGSILTIRLRIETQMEPPVAVGPNKVLTEQGPPIQGQRPSPNPSDFNTTSG", "length": 284 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJ61-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSTKNKHLMKGSKKGPKKKVADPFSKKDWYDGKAPAMLTKKRNIRKTLVTGTQRTKITSDGLKGHVFSSEPCQSAE", "length": 77 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FJT7-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKNPEVRKIHSAVFLITYLSTILGNLLIVVTMVTSQSLRSPMYFFLTSLSLMYVTYSSVIAPKMIVDSFSETTAISLEGCMAQLFAEHFFGGVGIILIIVMAYDHYVVCCLLLGGAWVGGSIHATIQLLFICQTPFCGPNVIDCFMCDLFTLLKLACMDTHLLGILVILNSGVMCMAIILILITSYVVILCSLKSYSFEGQHKALSTCGSHLIVVVLFFVPCIFLYVMPVATYPIDKAMAVSFTIVAPMLNPLTCTLRNAEVNNAMRKLWMKQNTLCYH", "length": 279 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKQ6-1", "protein_name": "Large ribosomal subunit protein uL5", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVQDQDEKKNPMWELGIHKLCLNICEGESGNRLTRAAEVLKQLTGQSPVFSKARYTVRSFGIRRNEKIAVHCTVRGAKAEEIFERHLRVREYKVQEHISLGTKYDPSIGIYSLDFYVVLGRPGFSFADKKHRTGCIGAKHGISKEDAMSWFQQKYDEIILPGK", "length": 163 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FKY3-1", "protein_name": "Large ribosomal subunit protein eL27", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGKFVKPGKVVLVLAGRYSGRKAVIVKNTDDGTSDQPYSHALVAGIDRYPRKVTAAMGKKKIAKSSKIQSFVKYSVDIPLHKTVVNKDVFRDPALKRKARREAKVKFEERYKTGKNKCFFQKLRF", "length": 125 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FLM5-1", "protein_name": "Small ribosomal subunit protein uS14", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGHQQLYWSHLRKFGQGSRSCCVCSNWHGLIRKYSLDMCHQRFCQHMKDPGFIRLD", "length": 56 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FNC8-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGQRNQTSSLADFILEGLFDDSPAHAFLFSLTMVVFLIAVSGNTLTILLICADPRLHTPMYVLLTNYLSGTKSISFVGCATQYFLFLSLGCAECILLTFMSYDRYVAICHPLRYAVLMNRKVGQMMAVMSWLGASVNSLIHTVILMHFPFCGHRNIHHFYCEFPAVVQLVCGDITVYEIAVYIGDIVLLLLPIALISASYVFILHSVIRMHSAGGKRNAFATCSSHLTVVSLWFGACIFSYMRPRSQRTPLQDKVGSVFYTIITPTLNPLIYTLRNKDIAKALKRVLGREMITQNPKVRLP", "length": 301 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP10-1", "protein_name": "Ribosomal protein L19", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVLRLQKRLASSVLRCGKKKVWLDPDETREIANAKSRQQIWKLIKDGLSIQKPGTVHSRARCQKNTLRKGTASAGMPKKSVPERDGNVFKNKRILMEHTHQLKADKARKKLLADQPEARRSKTKEARKRRQERLQAKKEERNRTEVETKFCRLI", "length": 155 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FP36-1", "protein_name": "Small ribosomal subunit protein eS24", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQDTASIRTRKFRTNQLLPGKQRVIRVLHPGKATVPKTEIWGKLAKMNKRTPDVIFVFGFRTHFGGGKTTGFGMSHDSLDDYTKTNEPKHKRARHGLYEKSKTSRKQRKERKNRMKKVGGTAKANAGAGQKGGV", "length": 134 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8W4FQE1-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTALNHTGVSHTVFYLLGIPGLEDQHLWISIPFFISYVTALLGNSLLIFLILTRRSLHEPMFLFLCMLAGADLVLSTCTVPQALAIFWFRAGEISLDRCITQLFFIHSIFIFESGLLLVMAFDRYVAICYPLRYTTILTHTLIGKIGVTIVLRSYCAIFPIIFLLKRLTFCRSNVLPHTGCEHIGLAKYACNDIRVNIWYGLFVIVSTLFLDVLLIFVSYMLILHAVFHMPSQDARHKALNTCGSHVSVIILFYGPGFFTTLTQRFGRHIPAHIHILLANVCVLVPPMLNPIIYGIKTKAIREQVAHLLFPKQK", "length": 314 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7F7T0-1", "protein_name": "Protein transport protein Sec61 subunit gamma", "gene_name": "LOC100757015", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDYVMQFVEPSGQFVKDSIWLVKRCTKLDRKEFQKVAMSTAMVFAIMGFTGFVKLIHIPVNNIIVGG", "length": 67 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GY23-1", "protein_name": "Tetratricopeptide repeat protein 16 isoform X2", "gene_name": "Ttc16", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MTDSSTEESVNVQTQKIPKLQVPETRETTLQRIFGTSQVFYSVSGVVKPRLTESTVPFRVREYYHQGHHCLEQEDWEMAVLYFSRALHLNPDQVEFYIFRAEAFIQLCDFSSALQNLRRAYSYEPENSKYLERLAFVLYLQGQCLYELCDFQEALYVFLQASDLQPQNPSFSYRCMACLLALNRHQDCLSLVTREVKQGRATADVYILRARIYNFFQKPKLCYQDLRSALLFNPKHPQAKGLLQVMVDQAKKSLQDASILAVQGKLHRALKRISCAIENNPLDPNLFLFRGTLHRRLQQFDPAVEDFLKAMDMVTDSQDNLVQKTQRQLLLTYNDFAVHCYTQGAYQEGVLLLNKAIRDEQNEKGLYINRGDCFFQLGNLAFAEADYKQALELCPKDEGANLRMGVLQEKMGLCEQTRRQFQKAEDHFSAAIKYNPVNAQYYLHRAKNRQLLQNIVGACQDIATVLLLNPKYPKMAPLMAKLFPGMSVEEVLNSHVAQLAKLQLRRMIESGPKASHPQSIVAKRLIERQKAQALMESWNWEQLFTRNPEEEVAPSESLQGKTLREKIEFKREVVEEKKVKILRKVTSLSDSYVDQTSSGSEFSILSPSTLETEVSTMEYKSTSNTAASSAERLLPQYLVTTKYKESLGLSMAPNVTQVSEDLHKSLTENIPDDGPRHHSSKAEATQRPKPRKTEPSQSLGKQRPSQRPSITEATKGPKPRKNRPALSPRQRLRRAKAVQAQNWKPRTNSNSQKTSSLLSNIAVIISSSNEAQDQSPVPSKADDISSYNDSTATSSTNTDSLRLSIHLSKPKYSKDQSPSHNKEEVSPTSNNYAAP", "length": 835 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7GZF8-1", "protein_name": "Protein EURL homolog isoform X2", "gene_name": "C4H21orf91", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MIIKRKATVIHHKGTMNEEEQFVNIDLNDDNICSVCKLGTDKETLSFCHICFELNLEGVPKSNLLHTRSLRGHKDCFEKYHLIANQDCSRSKLSKSTYEGVKTLLTKKINWIVQYAQNKDMDLDSECSKNTRHHLFNFRHKPDKKLLPQFDSQVPKYSVKGIAGSTGGLSSYTQRILEQRENTDFGLAILQDSDALWPHKHNQAQKKEETSSGPENVQTQNPRYSREELNSMTLDEVEQLNTKLQQQIQEVFEELTHQVQEKDSLASELHVRHVAIEQLLKNYSKLPCLQVGRAGPRSHLPINN", "length": 304 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A9J7JMJ4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100771730", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDFVNISLVTEFFLVGLTDQPELQMPLFFLFLAVYLITALGNLCLIILTVLNSNLHTPMYFFLFNLSFIDICYCSVFTPQMLMNFILRENIISYMECMAQVFFFCFFVVSECYVLTSMAYDRYMAIYNPLLYNVVMSPNLCLNLMFGSYFIGFSNAVAHTVCMLRLTFCDTNIINHYFCDIPPLLQLSCTSTYVNKLVIFVFASINIIVPTSTILVSYGFILSSIFHISSSEGRSKAFSTCSSHIIAVSLFFGSGALVYFKPSSAVYMNEGKISSVFYTNVVPMLNPLIYSLRNKDIKVALMKSLNSRNL", "length": 310 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AA74KSW7-1", "protein_name": "Predicted gene 3002", "gene_name": "Gm3002", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLNSSKLGVWAAGVPPSSPTLLFRRWVMKVESLISQPMTSGKNELQDHLIFISEKALHKRLFQKENGDEGVTRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSPAESRTWHRPGHDLPQREVLEEEH", "length": 280 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AAA9RU54-1", "protein_name": "Small integral membrane protein 17", "gene_name": "SMIM17", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQSLRPEQVRGLLEPERAKTLLPRENKAWEKRAAFAKDWVAVEVGASGCGSDEKDLPSPKTLVPQEWSSVEEDDESEDSQPHWAAALPTSPSCPSQDTGTGSGADLCLQCSSPRTPPWLPWAFSHTIESALPTPPRAWLWSLL", "length": 143 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0AAA9RY85-1", "protein_name": "Core Histone H2A/H2B/H3 domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNMPEPAKSAPAPKKGSKKAVTKAQKKDSKKRKRSRKESYSVYVYKVLKQVHPDTGISSKALGIMNSFLNDIFERITGKTSRLVHYNKRSTITSREIQTTVRLLLPGELAKHAESEGTKAVTSIPALSKYNMPSRC", "length": 136 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0KVZ2-1", "protein_name": "Eukaryotic translation initiation factor 1", "gene_name": "Eif1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EFGFRSVASAGWGAACPLGLRHVISCGGRAGLEQKARALSSSSTGLFPEGQQRAPPDFSDDICTDKKKNQERGINKWPTTTRNKNYFFVDPFADASKGDDLLPAGTEDYIHIRIQQRNGRKTLTTVQGIADDYDKKKLVKAFKKKFACNGTVIEHPEYGEVIQLQGDQRKNICQFLIEIGLAKDDQLKVHGF", "length": 192 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L002-1", "protein_name": "Oocyte specific homeobox 2 like 1", "gene_name": "Obox2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ILQSVQNTDMIEGPSFLPKFQMSSYTPMDTSSQLPQEPSWNLAFQMGQSPLVTSRTPMQSSPSVPEQNLNWQESQGSSRESSIQMQPGPVMDPGFPTLRSPSGHPSHQRPSRPSSRSGFHVPIEPMALSDKHGGKQTGPVAPRKCRKERTQYSAKQKSVLQEHFAECQYPDKKLCLELATLFGVTENEIKVWFKNNRAKCKQKNVPEALPETNGGPEAVSWSTDFPGSIAVVGCDQGEPMATAILDVDSTPKLNCSQESSLDGNWTYDGAMCCLPEDVLDGNDPVTAGDSGESAPVEAQSDLAAAGAPVAMAVDTQNPEECEDLPLLDEGVWQWMLEDFHQLEDWFTKNYIESPSSASHPLD", "length": 362 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LHI6-1", "protein_name": "CD27 antigen", "gene_name": "Cd27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWPPLYWLCMLGTLVGLLATPAPNNCPDRHYWIGAGLCCQMCGPGTFLVKHCDQDRAAAQCDPCIPGTSFSPDYHTRPHCESCRHCNSGFLIRNCTVTANAECTCSKGWQCRDQECTECDPPLNPALTSQPSEAPSPQLPPPTHLPYATEKPSWPPQRQLPDSTVYSRLPSQRPLCSSDCIRIFVTFSSMLLVFVLGGILFFHQRRNHGPNEDSQAVPEELCPYSCPREEEGSVIPIQEDYRKPEPASYP", "length": 251 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LYA6-1", "protein_name": "Prostate and testis expressed 2", "gene_name": "Pate2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSCLTSELQGSACLCLPSTGSYKHILQHLDLGTMCYKCKKYHLGLCYGLMRSCTLKHRQSCAAENFYILTNRGQSMYHYSRLSCMTNCEDINFLSFERRTELICCKHSSYCNLPMGL", "length": 118 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M6C3-1", "protein_name": "Prohibitin", "gene_name": "AABR07037878.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYNKNIKNSISISVCVGGVGGVRARAHAHAHTSPHACTRVIHAFVMLEVGPRDFVHIKKAFRGIDVKKPVIFDCRSQPRNVPVVTGSKDLQNVNITLRILFRPVTSQLPRIYTSIGLDYAERVLPSITSEILKSVVARFNAEELITQRELVSKQVSDDLTERAATFGLILDDVSLTHLTFGKEFTEAVEAKQVAQQEAETARFVVEKAEHQKAAAIISAEGDAKAAELIANSLATAGDGLIELRKLEAAEDIAYQLSSSQNITYLPVGPSSVGPSVRQSMFLRLPQ", "length": 286 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FXL6-1", "protein_name": "Cytochrome P450 2X10.2 isoform X2", "gene_name": "cyp2x10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDLRGIYSYMLSTVNSLVRDSSLTNFKKEFCVHAYLLSVCIQYQSSVWSSSRSVTMLTALVLLCLGAFLLYLQLRIRRPKNFPPGPAPVPIFGNLLQLNRISPLKDFDKFAQHYGSIYGIYIGSQPAVVLTGQKMIKEALITQAAEFSGRSNNMMFSHVTGGKGVIMADYGESWREHRRFALTTLRNFGLGKKSMEQRILEEVKHICLLLEESAGKSIDPQHLYHQAASNIIASVIFGSRFNYKDAYFQTLITSVEDLTKITIGPWAMLYEIAPVLRIFPLPFQKAFQYFEQITKHVLKVVEEHKTSRVAGEPRDLIDCYLEEMENKSDHRTSFDESQMVTLLFDLFIAGTETTSNTLRTLTLYLMTYTHIQEQCQREIDEVLGARDHVTYEDRNAMHFVQAVIHEGQRVADIAPLSMFHSAKTDTQLRGYSIPKGTIIIPYLSSSLREEGQWKFPHEFNPQNFLNEKGEFVKNDAFMPFSAGPRVCLGENLARMELFLILVTVLRRFRLVWPKDAGEPDFTYIYGGTQSVKPYRVIVEPRMHGEACKFVD", "length": 552 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58J797-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-233e3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANAKQLLKNSLDELVEAELKEFQWYLINDHRDISKAEMEKADRLKTVDKMVSCFGPKGAVKTTVDILRKINQNELAEELENKHKQGNCMSARAEGAVLETCKSPPFDYTNTSRELKKKLKEDYEKILVGNSQTGHKKYLEDIYTDLYVVENETGGRERQHEVIQMESKHNQQDRPLKCNDMFKVQPDTGRKHRRILTLGIAGVGKTVSVNKFILDWAEGKDNQEIVFIFPLPFRRLNLIKEEKYSLIGLLNKYFFSISGGLSSLPEKQGKVMFIFDGLDEYRFKLNFKKDDGFTDVNKEMTVSEIITNLLKRHLVPSSLMWITSRPAASSLIPRDLIDQVTEVRGFIDEQKEHYFIKNSSPEVARNIIGHIKKSRSLYIMCHIPVFCLISLTVLQPLLGQESNEKTPTTLTGMYINFLLSQKQQMKEKYRNDTESEANACSFDEIVLKLGKLAFKQLQKGQLIFYKTDLEKCGLDVRQGSVFSGLCTRMFQEENHYSGEQVYSFVHLSVQEFIAALYVFFTYKNKKANLFLDSWKKELKWKLSEKPLFKLHTAAVKKTLQSKNGHLDLFLRFLMGLSLESNQSDMKELLPWLKLKTGMIKDTTDYIKKKIEEENSAERTINLFHCLNELNDDFVEELQKSLCSGNLTAQDLSSAQWSGLVFVLLMSEETQEKFELQKYRRSDEALMRLIPVVKNTTRALLQCCNLTAQSCESLSSALQSSNCVLRELDLSNNDLQDSGVNLLSNGLKSPKCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGLKLLSQKLEDPNYTLNKLNLDHGGEKWFTAGLHKYACFLTLAPNTAHIELRLSEENRRVTRVGERQQYPDHPDRFDHHAHVLCRESVCGRCYWEIEMNAGDRVDIAVSYKSIKRKGRGYECVLGQNAQSWALICYVNRVAFRHNMIETRLPVKLMSRRIGVFVDHSAGTLIFHNIYRDSMSLIHSVQTTFTEPLYPGFWVEYGSSVKLC", "length": 1006 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JHM1-1", "protein_name": "Phoenix isoform X1", "gene_name": "pho", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLRSKGDTSVGEVMEADPRAELIFETPPPDVVSSINACFEEIDSALKIRRDPSVHSPPSDSDSESLFITQSVTKVVHTKRRLRSSKKPDSISDDSGYVRERRLSENQQTECEEESRSLRSSRRKRSKWEMYASARKATFPFLMKSLKTQHLPIRKHQILENSEVGGFFKCIKKIKTGSVKMGKVISSHLFQSPISDSSEEEDQNSEHDVISVDKALFVPGYKRGINFKWLPDFIRERRTLENYLSNGVDKEKKTEQIIEYRQRNQHPQRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDLEIAECAENSHEGHKVVIEETQRQTVEEASAHLEHEDDLNCKVVEYRKRKRHPKRTSAKALSKSSQVSKKPKKQDTHEVLASCSDHEDIESVECAENSHEDHNVVIEETQRQTVEEASAHLEHEDDLNCKNQPDVDQPNESNFIGPPQEGDISTQSDTQQTDSDIGSVDLFSPLNSPKRDDQIPNTTSITANVEENDQDSDVTQIESEGQHVSTFTQETQKCFANEEYDSDETHIDTESLSRFKPRTPNKQFTSTKHPEIPQFRVQSPKPPSRQAETVNVQLSPKHLPLSNVPLSEVPISPCESAIVGRQKTMVETETDSPMFKITGPSFLKRKRKRTKDKNAAADFKQHDTNGDVGQMVSCPGDDITGLKAVPIENIEACGVEHEMAIGEQTEELGLKSKELLEESVLSTVNSVSTKSKREKMKKYKVKECEAVENQLVETSKKAKKKKKDKERIATSYPEENNLTNIQSNEGFDSAELRVKEVNQSSQSLNTDQPTCVQTSEEITGETELKKKTTRHETDDPLYESVGLDVTLASQFDVGLRIDEQQEGLVTEEAERDERLQGKAMKVAKGKKKIQDTSFQVDHDIGLDKQRSDSGAKPANLDLDGLESLTIKKKKKKKKKHKLKEKTDPKLDFDFDHNVQFFQTDRLQTTDSVLLDSTHTNKQKKKKLKCQNDTDQSSDLKQLHVVGSKLQTIDLPKTDKHMERTGVSSSDALLEHMDDRTLGMRENNTIQTDQIEHLQTSEEVTRCSSPRLSSDKKREKTSVHPNLDASSVFQFDGFKANEDQAITQNTTKEKQISSEQLENNLVGPPSQVENIANVNSSVLLDHTHMNTLREGQLKEQTYKELALAFGLKQLCIVVNKLKTTDLPKTNKNMEGTGVGSSDELLKHTDDRTLETRENNTIQTNQIEHLQTSEKVERHSSPRVTRLSFAKKWMKTSVDSNLDASSGSQFDGLNSMAKEDWTFSQNMDLPLKRTKNKQKDKERTGVSSDALLKRMDDRPPEMRKKNTIQTNQIEYLQTSEKVTRRSSPRLTRLSLAKKMEKTSVDPNLDASSGSQFDGLKEASKEDRTAPRNSIEEKQSDAISSEGLENNPAHLVSTNKSDNTSPSSQVDNIVGLQSDANSVLLDHTHTDKQKKKKIKHKLIEQTEKELTSEVEDNVQPFQFIELRAMDLPSKRITNKKLKDRKRTGVSSSDAVLKHIDDGPSDMRENNSIQTDKIEHLQTSEEMTRCPSPRLSSDKKRKKKYVDTNLDASSGFQFNWSNGMAKEYSKNSTNISSLDNMHTSKQKKKKKQKLKEQKNVESVGDNVYSLEPDQFSGLQITEIKTKKKDKKRTKQANVEENDLKGILSNKAFKASQTYQLEHIQTSEEIKGRSPNAASKSAKKKKKKKNETKNPQYESVNLDLSLAKEDRTTTQNHTEETQGDGNAVEHLEMNPAGLIKVSKKKKKRENAGIVQLDNIIGLQSGSSTDVKSSVLSDSTDTNKHKKKKRKTLKEQENVEAEGDDVQSVEPDPFSGLQITEMTTKKKRKHKRCEEQRCLRGVSSHEAFKAPPTNLLQHIQTSEEISQCQSPNVAALENGGSPYQLENITEMQPGNSIDINSSEILYSTCTHKQKWKKLKQQENVEADANDVHSAELNLFSELKISEPTTKKKKHKKCVEKCALKDISSNEGIKAPQTSQLEHVQTSKEITQCQSPNAATLKSEKKKKQKRDETEVPQYLDASSVSQFDDVTRLKKQAKVDRTTTQNSSEETQNDDISSKQLEMNPAHLIKVSKRKKKREKAGSPYKVDKIVGLQSGNFTDVNFSQLSDSKRTDKQKKKKKIKLKEQENAEADVDDVHSVELDQFSGLQITKPTTKKKRKHKRCVEESGLRDISSNEAYKAPQTNQLEHIQTSEEITPFQAPNVAALKSAKKKKKKRDKTVEPQCLDASSVSQFDDVKTRAKEDQTLTPNSSKETQGDDSAVECLETNPAGLMKVSKKKKKRENAASPYKVDNIVGLESGNSADVSSSVPSDSTDTNKHKKKKRKKLKKQEIVEADLQTSEEIIQCQSPNVATLKSVKKKKDETKEHQRLDVSSVSQFDDVSRLKKRAKEDRTTIQNSSEETQSADISSEQLEINPAHLIKVSKRKKKRENGRSPSQVGNIVGLQSGNFTDISSSVLSDSTRTDKQKSKQKKKLKEQENVEADANDFHSAEPDQFSGLQITEMTTKKKKKHKRCVEESGLRDISSNYAFKAPQTNQLEHVQTSEEITQCQSPNVAALKSEKKKKNKRDKTDKPQYLDESSVSQFDDVKKRAKADRTTTHNSSEETQKDNISSECLELNPAHLMKISKRKRENKSLGLLSENTADLNSSSLLDGTDTDKHKKKKRKKLEGQENVEADVDDVHSAEPDQFSELQIPEMTTKKKKKHKRCVEESGLKDISSNEALKALQTNQLEHIETSEEMTIKTVKKEKKKRDATEEPHYKSVDLDVSPTESTTEAKLNPTKHKKKRKQSFSGSHDAHEAPERKRKKDRN", "length": 2809 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0MGZ5-1", "protein_name": "Heparan-sulfate 6-O-sulfotransferase 1-B", "gene_name": "hs6st1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNDTERNMVERTSKFLLIVVGSVFFMLILYQYVAPGVINFGSPHGYLLGEEDMTIFPTPDPHYVKKYYFPIKDLERKIDFEIKGEDVIVFLHIQKTGGTTFGRHLVQNVRLELPCDCRPGQKKCTCYRPNRKETWLFSRFSTGWSCGLHADWTELTNCVPGVLNKRESKSKKMRKFYYITLLRDPVSRYLSEWRHVQRGATWKTSLHMCDGRTPTPEELPPCYEGTDWSGCTLQQFMDCPYNLANNRQVRMLADLSLVGCYNLSTVPEKRRSQLLLESAKKNLRDMAFYGLTEFQRKTQYLFERTFHLKFIRPFMQYNSTRAAGVDLDNDTIQRIEELNDLDMKLYDYAKDLFQQRYQYKHMLDRREQRLLRGHASFHSPFREDGAGGEGTARLPTEDYMNHIINGW", "length": 407 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1EC97-1", "protein_name": "Dual specificity phosphatase 14", "gene_name": "Dusp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSRGHSTLPRTLMAPRMISEGDIGGIAQITSSLFLGRASVASNRHLLQARGITCVVNATIEIPNFNWPQFEYVKVPLADIPHAPIRLYFDTVADKIHSVSKKHGATLVHCAAGVSRSATLCIAYLMKFHNLCLLEAYNWVKARRPVIRPNLGFWRQLIDYESQLFGKSSVKMVQTPYGIIPDVYEKESRHLMPYWGI", "length": 198 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1XQX2-1", "protein_name": "Neurexin-1b", "gene_name": "nrxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMILHLGAHLLFIGLIVCKANAGSSLRFTGSDEQWVAFPMWNACCESEMSFSVKTTHLNGLLVYFDDEGFCDFLELHVHVGKLRLCFSIFCAESTCVLSDVAINDNRWHSVSIMRNFRNTTLIVDDEVKWEEVKSKRRDMTVFSHLFLGGIPSELRSVSLQLTSKTVKDHTSFTGWIMDVKVNDSEPAIISSAGVHEDLCGSENTCLNGGVCSVVEDKPTCDCSQTGYQGKDCSEGLAHLMMLDRGMEEYVATFRGSEYFCYDLSLNPIQSSSDEITLSFRTLQRNGLMLHTGKIADYVNLALKNGAVSLVINLGSGAFEALVEPVNGKFNDNEWHDVKVLRNLRQHSGVGYAMVTISVDGILTTTGYTQEEYTMLGSDDFLYVGGSPSTADLPGSPVSNNFMGCLREVVYKNNDAELELSRLAYQGDPKLQIHGVVAFKCESVATLDAITFETPESFLTLPKWNAKKSGSISFDFRTTEPNGLLLFSCGRAKQHNKEAKSPVTLKVDFFAIEMLDGLLYLLLDMGSGTTKTLALNKKVNDGEWYHVDFQRDGKSGTISINSVRTPYLCPGDSELLDLDDPLYLGGVPESSSGTVFPTGAWSALLNYGYVGCVRDLFIDGRSVDVRRAAELQRAAGVKPSCGKEPSGKCVSEPCLNRGVCREGWSRYICDCTGTGFLGHSCERDATILSFDGSKFLKVQFSAAMHTEAEDVSLRFRSLRAYGVLMASTSTHTTDTLRLELEAGRVRLTVNLDCNRINCTTSKGPESLFAGQNLNDDEWHTVRVIRRGKSLKLSVDDLPTVDGEIPGDHTQLEFHNIETGIITGKRQLPTMPSNFIGHLQSLMFNGKPYIDLCKNGDIDYCQTNAPIGFKSIIADPVTFKSCSSYVTLPSLQAYYYMYLFFQFKTTSADGLILYNSGDGNDFIAVELVKGYLHYISDLGNGAHLIKGNSIKPLNDNHWHNVMISRDPNNLHTVRIDTKTTSQTTLGAKNLDLKGDLFVGGVPEQMYKDLPKLVHAKEGFQGCLASVDLNGRLPDLMTEALVCIGQIERGCEGPSSSCEEDSCANQGVCLQQWENFTCDCSMTTYAGPLCADPGSTYVFGRQGGVITYSWPPHDRPSTRVDRLALGFITLMEDATLVRVDSSAGLGDYLKLHIVKGNVVAVFNVGTYDINIEENGKLVNDGNYHIVRLTRSGGNATLQVDDLPVIERFPPGHIDSHRLGTGRLPYRRLVEESLPKNGRQLTIFNSQMTIRIGGWQKQQVSGFQGQMSGFYYNGLKVFSMAADGDPNVRMEGSVRLVGELQSSSTPHGGATVYQSSVTEISSTTSNTITITYSTPADEQQTTDELLVASAECPSDDEDIDPCEPSSGTLCCFVPPAGPTGPAISSFPGPAEVFRESNGTTGMVVGIVAGAALCILILLYAMYKYRNRDEGSYHVDESRNYICNSNGAALKEKNTADDDSGSKSKKNKNKEYYV", "length": 1470 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2A7I1-1", "protein_name": "Zinc finger protein 978", "gene_name": "Zfp978", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFAPHQESGRRTTKRMSASLENTAQCLLTFKDVFLDFSSEEWECLNFAQRTLYMDVMLENYNNLLFVENHCICGNYEKEKVVEQDTQHIFNEHGHIQEKSFKCNESSNIIHESSESTPHKTNHRDATLQSSNLKRHKTGTTKQVCTYKDCVNCLKGSSIISLNQGTHVEKKEHNRNKNLDEVLVSKHKPIVRQNNSEMNTYTCGEFDKCFTQSDNLQSQQRIYPGKKSYKYSESDKCFTQPSHLSIHHTIHSGEKPYKCSECDKCFTDKCTLRKHQRIHTGEKPYKCNECDKCFTDKGSLRVHQRIHTGEKPYKCSECDKCFTQTSHLSIHRRIH", "length": 335 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A8N2-1", "protein_name": "PRAME like 25", "gene_name": "Pramel25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICGHCPDQDESLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPEWPFPYLSLGKQINNCNLETLKAILEGLDILLAQKVQTSRCKLRVINWRDHDLNLWAGSHEGEGLSEFTTEKQPIENSPGCEVKKELKVMTEVLRMKGRLDESTTYLLQWAQQRTDSINLFCRKLVIEGLTKASVIEIFKTVHADCIQELILRRICIEELAFLNPYLKLMKRLFTLTLDHIIGTFSFGDSEKLDEEIIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDYLPYCLNICELKHLHLSDICLRDLLLEPLGFLLERVGDTLKILELESCCIVDFQFSALLPALSQCSHLREVTFYDNNFSLPFLKQLLHHTALLSQLISECYPAPLECYDDSGVILTHRLESFCPELLDILKAKRQLQSVSFETTQCSKCGGCYIYDQETQCCHFVELLLA", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2A9Q9-1", "protein_name": "MAGE family member B5B", "gene_name": "Mageb5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRGQKNKHHRNRLKNKKHNQEKVHPQKDESQEKGHHKRDDFQDHKEARDNAAVEEKSSCSSPSVPGETLEKPPASKTSSDAGWLSCVSSPATVCGDELEFDDGTYFHCGGNSLYSEYRTCQENPCKHCLDMYVNLVEQYVLYKFKMKKLIDRNKLIDLIEPKYRYNFSDIFKRAFENIEIVFAASVIEIDSTNHVYDLVSKLKLPNKGRVCPGRGLPKTGLLMTILAMIFMNGTSASEEDIWKFLNYMQVYPGRKHFIYREPRKLITQDFVKLKYLEYKQISLSDPPCYRFQWGPKAYTETTKMKVLEFMAKGSGVEPSTFSVQYTEALREENQKTKIRKWYPILAQKHCPGHSHQHVQKVMKPQ", "length": 366 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ADW8-1", "protein_name": "Predicted gene 15128", "gene_name": "Gm15128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANREDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHDSRRSRNRFRRAPVQSERSHVYSGRTNNYTDRPQHDLSNRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIAHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESFDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW6-1", "protein_name": "PRAME like 22", "gene_name": "Pramel22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHRLLREEALAISSLKDLPNMLFPVLFEEAFIFGYTKILKAMIPEWPFPYLSIAVLIDNCNLESLKAVLEGLDILLAQKVHSSRCKLKEISWRDTNHGLDGIRPGSHEVEGLSEFMEQKHPNCVEKKELKVTTELSVMNGRLNESDTYLLEWTQQRKDSIHLFCRKLVIQSLTKATVIEIFKIVNADCIPELELCSLCLEDLAFLNPYLRQMDNLLELTLDHITDSLSIGDSEMLEERMITLVSQLPTFPCLQKLCINDVYFIYGNLKEFLGCLKKPLVSFCISNCELSQSDLDYLPYCLNIFELKCLYIINIHLQYLCLEPLGFLLESVRHTLGCLALKSCNMGEPHFKSLLPALSQCFHLTDVNFQENELSLLSLKQLLQHTSKLTQLSYEMYPAPHECYDDRGVILSHRIEQFCPEVLDMLRAKRQPKDINFVTTQCSKCGIYYVYDLETQRCRFLK", "length": 460 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AGW7-1", "protein_name": "PRAME like 23", "gene_name": "Pramel23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNVNSPPTLMKLASQRLLREEALAISALKDLPNMLFPVMFEEAFINGHTKILKAMIPLWPFPYFSLGMMIKNLTLDTLKAVLQEIDILISKVVHSSRCKLKEIKWKNTDYGLQGIWPGSHEFDGLSEFMEQKQPDCGVKKELKVITHLKLMEGSLDECATYLLQWAQQRKDSIHLCCRKLKIQGSINATVIEIFKIVHADCIQELELCCLCLEDLDFLNPYLKQINNLIRLKLDEIKGTVSMGESRNIDEEKVITLISQLPTLQHLEKLCINDVSFIEGNLKECLRCLKKTLEILCITNCYLLQSDLDYLPYCLNILELKCLDFSNIPLSHLFLEHLRFLFERVRHTLECPILKSCEMGESQFNSLLPAISQCCQLTEVNFYDNELSLIFLKKFLHHTAKLSQLTYELYPAPLECYDNRDIILSHRLENFCPELLNILRAKKTAQGGHLCYNPML", "length": 455 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AHC7-1", "protein_name": "SSX member B14", "gene_name": "Ssxb14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVISCEKIPMEVLHKPKNICKAFQDISTYFSGEEWGKLTEWQKSAYMYMKRNYTRMTGVTVNQPVFMSGKEQAKQSLVKGIEVHDSEDECFEESFGVTPRKRMKLTSVTISIHNVEGSLASGENDSNLAETDGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 168 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AK42-1", "protein_name": "Pre-mRNA-splicing factor CWC22 homolog", "gene_name": "Cwc22rt5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSVAHMKQSSGHNRRETHSSYCRSSSPEDRYTEQERFPRDRDYSDYSRSDYERSRRGYSYDDSMESRSRDREKRRERERDADHRKRPWKSPSPDRSPARGIRQSSPQEEPTWKKKKDELDPLLTRTGGAYIPPAKLRMMQEQITDKSSLAYQRMSWEALKKSINGLINKVNISNISIIIQELLQENIVRGRGLLSRSVLQAQSASPIFTHVYAALVAIINSKFPQIGELILKRLILNFRKGYRRNDKQLCLTASKFVAHLINQNVAHEVLCLEMLTLLLERPTDDSVEVAIGFLKECGLKLAQVSPRGINAIFERLRNILHESEIDKRVQYMIEVMFAVRKDGFKDHPVILEGLDLVEEDDQFTHMLPLEDDYNPEDVLNVFKMDPNFMENEEKYKAIKKEILDEGDSDSNTDQGAGSSEDEEEEEEEEEEEEEEGEDEEGGQKVTIHDKTEINLVSFRRTIYLAIQSSLDFEECAHKLLKMEFAESQTKELCNMILDCCAQQRTYENFFGLLAGRFCMLEKEYMESFESIFKEQYDTIHRLETNKLRNVAKVFAHLLYTDSLPWSVLECIKLSEETTTSSSRIFVKIFFQELCEYMGLPKLNARLKDETLQPFFEGLLPRDNPRNTRFAINFFTSIGLGGLTDELREHLKNTPKVIVAQKPEAEQKKTALTSSSSESSSASDSSDSDSDSSESSSESSSEASDSSSSSSTQSSTSAKGTRKKRQGKARGEEVDKLARGHQALERRQGGREDQRHQEGRTERARSERHRAQNSRDADWRDSLAKHIDDRSHENSHSRVGNGREQGSHREPEDRHGEPKKKQREKRFFL", "length": 830 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE0-1", "protein_name": "Reproductive homeobox 2F", "gene_name": "Rhox2f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYLLDVGPEEDEENANGVKTLMVLLAGDGRNEGESGRGLPGSGASAAEGYRAGEISAGGPAAQVADLMDDSNQEDLGATACDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHLWRHSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ANE1-1", "protein_name": "Reproductive homeobox 3F", "gene_name": "Rhox3f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSMSNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDNTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEALRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREKYRWYKRL", "length": 215 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ASJ1-1", "protein_name": "PRAME like 14", "gene_name": "Pramel14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLEAPPTLLQLAAQCTVRKEVLTISVLQNLPMKLFPPLFKEADILRKAKMIKLLVEYWPYPSLLVGLLIDKTNLETFQAILEGVGTWLKRKYRPRMGKLQVVDLRNGHHDFWDMLAGREGGDQLVETMPEKQEVEGHSRRQRLRVFSDLSFKSSRHEDKQQTHLLQWAKDREGFLHLCCEKLEIGALGVSKVKKVLKLLQPEFIKELELNTVGNLSKLTKLVPCISKMRNLQKLMLVRIFGRHTYTPLEERNVTKILSLFPKLSYLQHLTIDDVYFLRDHMNELFRYLEAPLLSLTITLCQISQSDLESFSQHWNYGQLKHLCLKGVSLSTLNVTPLKFFLESVADTLQTLELEDCRMKDSHLRILLPALTKCTRLTSINFYDNNISRDVLQDLLHRTANMSQLTMELYPAPVEVYNEWSYVQVERFSQLCAELMNTLITVRRPKSVCFGTYSCYDCDTHCIYGNQTTFCECLE", "length": 475 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ATW2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4x15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADIHNVTEFFFLGLSSNQEVQRVCFVIFLFLYMAIVLGNLLMVVIVAVSRNLGSPMYFFLSSLSFVEICYSSTTAPKLIVDLLAEKKSISVWGCMAQLFFMHFFGGIEMFLLMMMAYDRYVAICKPLHYTSIMNRQVCTVLVGMAWMGGFVHSLAQVLLIFRLPFCGPNIIDHYFCDVLPVLKLVCSDTFLIGLLIVVNGGTLTVISFVVLLSSYAVILFHLRTQSAEGRRKALSTCGSHVTVVVIFFAPCVFIYLRPTATLPIDKMVTVFYTVITPLLNPIIYSLRNAEVKKVIKILCTRATKVDKK", "length": 309 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWL9-1", "protein_name": "Reproductive homeobox 2C", "gene_name": "Rhox2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSVNYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGASAAEGYRAGELSAGGLAAPVADLMDNSNQEDLGATGCDQEKEKQPEEPVPDSMGDLENVKRVSGPWSTVNPVRVLVPKFRHGWQQSFNVLQLQELESIFQCNHYISTKEANRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AWM0-1", "protein_name": "Reproductive homeobox 3C", "gene_name": "Rhox3c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVERAGRNLFQVNGHRSALLPELPQDYHRASRSVYGCETKMDSTQGTKVLPAEEARNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BED8-1", "protein_name": "Predicted gene, 58953", "gene_name": "Samt1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQFVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEE3-1", "protein_name": "Spermatogenesis associated multipass transmembrane protein 1d", "gene_name": "Samt1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQLIVDTRSVIYRFINEKDCIYKLSGLLSSLAAFMLEVLIASILSWRLWEFDSNVVQLVSFGLFEAYYPQQFNISGTLTKMLVYTPIDSTWNISTEFMYAQNLVVWAILMKPVVLVFCVMAIKISCTKNPLVEMQIYCYKISALILSVSSMFTFVSVIWNHMVDFYGHTTLDFPSDFPVKKEALTSKHLTVVLPVGLLIATMSLFGVIMFLSEISDLKLKRPVKANDASKMGLLDA", "length": 237 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI6-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 10", "gene_name": "Msantd5f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLAWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BEI8-1", "protein_name": "Myb/SANT DNA binding domain containing 5 family member 8", "gene_name": "Msantd5f8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQREDNRVQSVRSDKEANRRRRLRQEGQSSSGPCDSPWTEDEIWILLQEWAMVEYELGDPGNKMHAKAKSLSRRLSNRGLRKSKNSCLDVMVKMKDLHTRLCNERPRAYRLYSTYEWILYEILGHPRSQGGYVPGLWFDGHSKPPASYAPSLCIGGAISPGPSFSPWTDPEIKIFLQEWQVVEREIGHPGQKIKQKSSLVCQRLYHRGLFKDIQSCLDLMWTLKDLHSTLSRERSRTVPLFSPYRDYLERIFDPKCQRGHVPGALYNWSGYHRPSSSPQTPMVMPSPVYQPWDYGMSASSGQLHGNPSLIMSSQDSLVPRWDAWNATYPLPVQHVLLASLSGDNNFQLVWSPRDESSSPQ", "length": 360 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFR3-1", "protein_name": "Histone H2A", "gene_name": "H2al1j", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTHSQRGEFPLSLVDRFLPEGNHSGRLSSSAPVILDSVLEYLSSNILELAGEVAYTTGRKRIAPEDVGLVVQNNEQLCQLFKPGATSVFDPPEPDDN", "length": 109 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFZ7-1", "protein_name": "BTB domain containing 35, family member 9", "gene_name": "Btbd35f11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BH64-1", "protein_name": "Secretoglobin, family 1B, member 30", "gene_name": "Scgb1b30", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLTGALLLLGAALLLTSEGDCGLCPVLQKKVHKFFDGTTEEYVEYLKQYNNDPLVLENAANIKKCSDRMLAEEDKTQATNFINKVTGSRSC", "length": 92 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BHG6-1", "protein_name": "BTB domain containing 35, family member 7", "gene_name": "Btbd35f7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSFGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI40-1", "protein_name": "X-linked lymphocyte-regulated 4A", "gene_name": "Xlr4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSDDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKTVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI45-1", "protein_name": "X-linked lymphocyte-regulated 5A", "gene_name": "Xlr5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKKKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQHTIVEKEISKVQNRVIMETQDQDISMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI50-1", "protein_name": "X-linked lymphocyte-regulated 5B", "gene_name": "Xlr5b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNKEQKAMKKSGKHQRVHKTLPSDDFKNSDEVNPADKPAVGTSGMGSHSSGSDMQEAREPVQKKMQDFKGDDGTGLLMEKRKQFEEDVNASFRSLNENLQSILKAQQNSRQELKSLYCERFGSVYHNWLVEMDRTRDQEEYFSFITQQQMKILQTAIEDHETKLKNAKDMCDTFLKKANDLSKRQKTFIGGQQTIVEKEISKVQNRVIMETQDQDIAMVETYLQSLIHESSEETI", "length": 236 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BI74-1", "protein_name": "SSX member B6", "gene_name": "Ssxb6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSSCEKIPMEVLYEPKNICKAFQDISTYFSDEEWVKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMRGKEQAKQSLVEGIEIHDSDDECFEGSFGVTPIKRMKLTSVTISIHNVEGSHDSGENDSNLAETGGIQVNVWSHRLRERKYRVIYSEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BIM8-1", "protein_name": "Major urinary protein 18", "gene_name": "Mup18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 181 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CEK7-1", "protein_name": "Major urinary protein 14", "gene_name": "Mup14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG71-1", "protein_name": "BTB domain containing 35, family member 19", "gene_name": "Btbd35f20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLQPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSVYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKMRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTLKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CG92-1", "protein_name": "BTB domain containing 35, family member 10", "gene_name": "Btbd35f10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIHALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2CGC2-1", "protein_name": "BTB domain containing 35, family member 3", "gene_name": "Btbd35f4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQRMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 496 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A3KG49-1", "protein_name": "PWWP domain containing 4C", "gene_name": "Pwwp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSSEYVLCGWKSQLCPARVLSRPRTPAHSKRRGVPFLEVQILPVGEKRRVRSSKVRPLAKSEIISINSLAGKESRGRGSPGQTRASRRALKVALDGLGEGSSFFQGGRAGSRRTSTLAPKVPKEQASSSSSSLGQRLRLRLRQLLPLSLCQRLHLHLRLRLHLHMHLCLQGRNQKGQGLSQRSPGKRVRPDPGPVMMGSQNVPAVPVGEAQAHTAAGLPRSEVEGDVLRGTRVWPSYSKKTPLGKAGGNPGKRKPGTGKRKLRSLSAPASRKGTRSKTEQQAASGPPRHISISPKALKQRVRCAGLEIRAAGAQRKTALAENKDHPGLGTPKPDSKRASAACMPPVLRLRRSLRIASRKKKTHVLCALCGLPEWEPQVHSKVTNTRFKRRGARVQKDAKATNVVSAQEPSTIEQGTLVWFKFQDLPFWPAVVKSVSKIDKMARVLLIEGNMQFERRGIRVPLRKLKHLDCGEKVSLVRRASRLYAQGINWCFSVIDHYREGLSRGSLLGSFMDYYTTQASYPLRRAVQEGDLHIDFPKVSYAELEDWEEETALGGKGPYKKLLPDRMRAAWDRANQKLVDFIVKRKGADQHLLDIVKGRKPSRWLDDLWKSKREVFCIETYLEDDDQLHLVARHLQEVAKEADEALLSLARGDKVRFTMEVLFPEAIIYSIAALDELSYKEAEEKYLRGPPVHYREKELFDKTILKAARKRSAARIRAARDPPVPTP", "length": 728 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A5WWD5-1", "protein_name": "alpha-1,2-Mannosidase", "gene_name": "man1b1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLPSTRKDFVSLTLSESGSYSNSKQWRRQSCWRKWKQLSRLQRSLILLTLMLLLVCGIATSPTLIGHWRGMNGDDVKNSFVVDLKNEYRSILPEPPSERKDFDRRGAFGLEKLLQGKVNVSGVLGDQNHGLDLKNADKGSEGQKPIISWRGAVIEEEQASDTDTKDTENQGDPASLALAESRLEAVREAFRHAWKGYKDFAWGHDELKPISKSYGEWFGLGLTLIDALDTMWILGLQEEFAEAREWVAKELSFDKNVDVNLFESTIRILGGLLSTYHLTGDNLFLDKAKEIGFRLMPAFSTPSKIPYSDVNIGKGTAHPPRWTSDSTVAEVTSIQLEFRELSRLTGDPKYKLAVMEVMKQVHKLDGKQDGLVPMFINTNNGLFTHQGIYTLGARADSYYEYLLKQWIQGGRIEQELLEDYLQAVEGVKKNLLKKSTPLGLTFVGELSHGHFSPKMDHLVCFLPGTLALGVHYGLPADHMELAKQLIETCYQMYAQMETGLSPEIAHFNMHDGSTQDVDVKIADRHNLLRPETVESLFYLYRLTRDKKYQQWGWEILQNFNKYTRVPTGGYTSINNVRDPSYTSPRDKMESFFLGETLKYFYLLFSEDPTLISLDKYVFNTEAHPLPVWPQAE", "length": 632 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCW0-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 3", "gene_name": "USP17L3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALASGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NCW7-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 4", "gene_name": "USP17L4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGYYFSYVKAQEGQWYKMDDAEVTVCSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATEESTLDHWKFPQEQNKMKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSMNSTDQESMNTGTLASLQGRTRRSKGKNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NDS4-1", "protein_name": "TBC1 domain family member 3B", "gene_name": "TBC1D3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNIEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDISGTLRKHMFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQSKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKQGDLPPPAKPEQGSSASRPVPASRGRKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NJZ7-1", "protein_name": "RIMS-binding protein 3C", "gene_name": "RIMBP3C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDSPSPLGASPKKPGCSSPAAAVLENQRRELEKLRAELEAERAGWRAERRRFAARERQLREEAERERRQLADRLRSKWEAQRSRELRQLQEEMQREREAEIRQLLRWKEAEQRQLQQLLHRERDGVVRQARELQRQLAEELVNRGHCSRPGASEVSAAQCRCRLQEVLAQLRWQTDGEQAARIRYLQAALEVERQLFLKYILAHFRGHPALSGSPDPQAVHSLEEPLPQTSSGSCHAPKPACQLGSLDSLSAEVGVRSRSLGLVSSACSSSPDGLLSTHASSLDCFAPACSRSLDSTRSLPKASKSEERPSSPDTSTPGSRRLSPPPSPLPPPPPPSAHRKLSNPRGGEGSESQPCEVLTPSPPGLGHHELIKLNWLLAKALWVLARRCYTLQEENKQLRRAGCPYQADEKVKRLKVKRAELTGLARRLADRARELQETNLRAVSAPIPGESCAGLELCQVFARQRARDLSEQASAPLAKDKQIEELRQECHLLQARVASGPCSDLHTGRGGPCTQWLNVRDLDRLQRESQREVLRLQRQLMLQQGNGGAWPEAGGQSATCEEVRRQMLALERELDQRRRECQELGTQAAPARRRGEEAETQLQAALLKNAWLAEENGRLQAKTDWVRKVEAENSEVRGHLGRACQERDASGLIAEQLLQQAARGQDRQQQLQRDPQKALCDLHPSWKEIQALQCRPGHPPEQPWETSQMPESQVKGSRRPKFHARPEDYAVSQPNRDIQEKREASLEESPVALGESASVPQVSETVPASQPLSKKTSSQSNSSSEGSMWATVPSSPTLDRDTASEVDDLEPDSVSLALEMGGSAAPAAPKLKIFMAQYNYNPFEGPNDHPEGELPLTAGDYIYIFGDMDEDGFYEGELDDGRRGLVPSNFVEQIPDSYIPGCLPAKSPDLGPSQLPAGQDEALEEDSLLSGKAQGMVDRGLCQMVRVGSKTEVATEILDTKTEACQLGLLQSMGKQGLSRPLLGTKGVLRMAPMQLHLQNVTATSANITWVYSSHRHPHVVYLDDREHALTPAGVSCYTFQGLCPGTHYRVRVEVRLPWDLLQVYWGTMSSTVTFDTLLAGPPYPPLDVLVERHASPGVLVVSWLPVTIDSAGSSNGVQVTGYAVYADGLKVCEVADATAGSTVLEFSQLQVPLTWQKVSVRTMSLCGESLDSVPAQIPEDFFMCHRWPETPPFSYTCGDPSTYRVTFPVCPQKLSLAPPSAKASPHNPGSCGEPQAKFLEAFFEEPPRRQSPVSNLGSEGECPSSGAGSQAQELAEAWEGCRKDLLFQKSPQNHRPPSVSDQPGEKENCYQHMGTSKSPAPGFIHLRTECGPRKEPCQEKAALERVLRQKQDAQGFTPPQLGASQQYASDFHNVLKEEQEALCLDLRGTERREERREPEPHSRQGQALGVKRGCQLHEPSSALCPAPSAKVIKMPRGGPQQLGTGANTPARVFVALSDYNPLVMSANLKAAEEELVFQKRQLLRVWGSQDTHDFYLSECNRQVGNIPGRLVAEMEVGTEQTDRRWRSPAQGHLPSVAHLEDFQGLIIPQGSSLVLQGNSKRLPLWTPKIMIAALDYDPGDGQMGGQGKGRLALRAGDVVMVYGPMDDQGFYYGELGGHRGLVPAHLLDHMSLHGH", "length": 1639 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A7TZG3-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 9", "gene_name": "Skint9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSASCLPGFFMSFLLLQNTVLTQAMRSDIKINIQVPDTEGLLLECTSGSLIPPAEMTWRDSNGNIIPHSTAFNSQDRDGLLYLKSSILLKNRAKGPITCSIYNVTTNQEKKRSIVLPDALFKSENMSLMSNKFSCPSIYLITIIFLNFLRGILVFCCLRRKPVCFRNLMSTVMEALYSKMGVCCLLIWECLLLVLYIAFLPIYVSFRSRAFLLDDTYPLYTNWLWNICIILTVIMVLFPGLILCLLWTLNCYGQVSSLPPTSMELSTKDSEQNSSKSDDSQENYDVNCKILETCESKIFSQHQESCEDDTASTLFIS", "length": 319 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A7XV14-1", "protein_name": "Selection and upkeep of intraepithelial T-cells protein 11", "gene_name": "Skint11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSASCLPGFFMVCILLKITVLTQVMSLDIQINTQIPDTEEGVLVECTAESLFPPAEMTWRDSKGNIIPPSSTFDSQDRAGLLCLKSTILLKNRTEGPITCSIYNKTTNQEKRRSIILSDVLFRPQYMSLMSNNLLYLGIYLIFILFLNFLKGILFCLTKRLVHFRKRMIKIKKVWSNKTRACCPLIWEFLEIVLFIAFLPLYLMFRIRVFTLDEAHILYNNWLWKVCKTLIAMMILFTVLILFLLWTLNRYGKMPCLSSMNIDVSTHDAEQNSSKSAKFQENYDVAGQMILETYEETIFCQHQESCEEYNYDPLLLSSLDALGTCEDEKFSQHQESFEEDEDLQSFSDFKIELYSKLGNLTH", "length": 364 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B0BMZ6-1", "protein_name": "Cilia- and flagella-associated protein 119", "gene_name": "Cfap119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MITPRSSQSLEMKVQTELEHSPKLQEEPDRSPSLVDSSVIRIGTDEQNESPAEATSSPVEVAEDPGANLFPPPLPQPRICMWKYLDIHSMHRLEKAATVEEMREVLAELLELGGPEQSLRDAIILDLFSHALIFCRQQGFSLEQTSAACALLQDLHKACVATPLGNVEECYRYFTSVLFCHGVRRPPFSIDLFKEEQLLALADYVVNTYFRHFKLYKYVFTPQVRLDLSLSYMGLQSLHLWPEEKEDEEATVEQAATPQEEEPEAVTEAEQQPSEVCILQTYIKCQLNKELRQLQQLVEERLKESEERLSNRLAALERPYQTPPSKGKSKAK", "length": 332 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0G0Z9-1", "protein_name": "Probable polyketide synthase 6", "gene_name": "pks6", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLKNIDLIEKGVAIVGIGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSEASLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGASNIDYQHTNKHQDSVLKNAIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSDISIVGGVNLILDVEMTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECVGVVVLKNLQDAIKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSAPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTAIQIYSKSNYLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQSTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNLNIELPLYQWSDELYFAQNQVLEQHRKGGPPIDHLGLSNSYYSPFKNSYKTLIDINYKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDHKSNEWIQSSNSNFQLLDHGNDIPSNYNIKEIIKNKCNLSKLTKNELYKNIKSKTGLNYTGVFQGVTECYIGDNCTLSVVSLESQTNSFLNIPILDTCLHGMLILINDQCQIVFDKAIGFKYYSSNIPADFKENKDSFYVYSNLRPRVGGDSYHGTIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFQSSLNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSFEEKDDTYFEFNKVIIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKIYKCSYLRKKNQVISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYHPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLTTNGQLVFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCGMPQQSWYQLLNSCNFKDIVMSKECIFFGSVIQAQKPPISLLNSQPKYDNIIIYGGSINSSFVENIKLDSNSKSLFQIETIQEFNKLISKSTITNDSIVYFIKTLETLSLDNFKQITLEYIEINQKLLQINSLCKHVLIVSDSRKTNYLASSAIGAARYFDEFPLLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKKIQIKPSKISHIEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGRDGFGLSTFEILKWKGFKSNLFVTVNSDKTKQYLLKKYGDLITGIYSNTDKSYVAEIKNKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLTKYGRIIDLNSNHLNQSEFLKNINFKYNHGYHNFELSLFQKNKILKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINDILNENQQIRNIDSIFHFAFQQIACKVQEINMKHLNISHGAKSMGAINLHNQSIKRNWKLINFVMASSALSFIDSTDQCTYACANTLLDSFSKYRVSLGLPSTCINLGLIESTGFVSKNESISVFLDGNGIIPTPINRVLGLLDLQIQNASKFTNSMISNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQNKYLPSNRIDYWKNEMKFEESIKPIPNEIRSRNNNSGKIILLTGTTGFLGGFLLFNMLRLDSCKLIYCLIRNKSKSSYPLDEIINNLKYHQLYEKLNKSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKNYNIPSILIRPPSIFLNPETGIGHSSDLTLLMIQSCYELGYCPNQILNGFILINTITWLSNNITNIIMNDNCWTNSKMNIYNVHGKQIQSSLIIKPLEKHFNCKQINNNDWIDMVNNSNKKSCIKLKSFHSLENIFKSENKGYKSNESQSISLSTKSLLESMGSYNTDLKITDKMIISHIKHIFK", "length": 2924 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G100-1", "protein_name": "Probable polyketide synthase 7", "gene_name": "pks7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNFKNINLIEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYLHTNKHQDSVLKNVIAQSTCAISNRISYCFDFNGPSLSIDTACSSSLNAISQGYHSILNGTSDISIVGGVNLILDVETTKAYSYLSMLSKTHGKCKAFDESGDGFTRGECAGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNEKLSVNEIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRKNEKPVSMMINNFGVTGSNCCLLISEFKKQDYEPYENNYKSNNKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLCQRSVIAASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLINSKLSKYYGYSVLEKLRSIGDDDTTSIHDPNISQPAVCMISVSLFELYCHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYHRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSVLKLNIQSNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIINPVRFTQTISNIYKHIESNQLNNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNKKIDLPLYQWSDETYFAQTQTLEQHREEGPPIDHLGISNSFISPFNNSYKTLIDINNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNQWTQSSNSNFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTHIKSKTGLNYTGVFKGVTECYIGDNCSLSVVSLESQTNSFLNIPILDTCLHGMLVLINDQCQIVFDKTIGFKYYSSNIPAYFKENKDCFYVYSHLKSKSADSYHGSIIVMLSDGSVLYEIQEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSQIPTPSYFKSIIYENDSFHSIVNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSRIISKLLFPLENDNDNEDLPQSLFQNGLMDKFYKCNNFKKKNQIISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVTLLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYLPLTIGESLIETQSIKPSYYDFVIMSNVLHVVKDIKQVVEQMYQLLTPNGQLVFVEPPYKSILIDSIVGSFDQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDIVMSKECIFGSVIQAQKPPISLLNSQPKHDNIIIYGGGNNSRFFENIKLYSNSKSLIQIETIQEFNQFINKSTITNDSIIYFIKTLETLSLDNFAQITLEYIEINKKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSKISHIEASSIPIDYLASFISLFNVGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFKSNLFVTVNSDETKQYLLDRYGDFISGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKNARIIDLTSNHLNQSEFLKNINFKYNHSYHNFQLSLFQKNKIQKCLNEISNAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRYLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSIDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYACANTLLDSFSKYRVSLGLPSACINFGSIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNSGKFTNSMLSNFKPSKFKNNQQISLFLKFDYLMNLKNNSEQTKKENIGNKNIDELFIEKVSELFSTDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTINISIKMILNSLMKNNQCGREI", "length": 2513 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G101-1", "protein_name": "Probable polyketide synthase 8/35", "gene_name": "pks8", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNLEIINLIDKGVAIVGVGFRIPSGNNENSICSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFNECKSFDPLFFGINPSDAHQIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSNIDYQHINKHQDSVLKNVIAQSAYAVSNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVGMIKAYSYLSMLSKTHGKCKAFDESGDGFTRGECATIVVLKNLQDAVKDGNRIYCVINGSSSNVDGGGHMDKVNLYSPSKQSQFNNINSAFKSTNGKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRINEKPVSMMINNFGVTGSNCCLLISEFKKQDYESYENNNNNKSNHKNILIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNYLYQRSVVIASNSNELFEKILNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNDEIFKKSIDLIDSKLSKYYGYSVWGKLTTIKDDDLTSIHDPIFAQPALCMLSVSLFEIYCHWGVNPSFILGHSLGEISAAYCSGMIDLDTFCYTVYYRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNDIVFIEIAPHPTISFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYSINFKCQLENKKSNQSINLPLYQWDDELYFAQTQTLEQYTKEGPPIDHLGLSNSYYSPFKNSYRTFIDINNKPFQYLKGHMVKGKYYFPGCGYIDIIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPSNYNIEEIIKNKCNLSKLTKNELYTQIKSKTGLNYTGVFQGATECYLGNDCSLSVLSLKSQTNSFLNIPILDTCLHGMLVLINDQSQIVFDKAIGFKYYSSNIPSDLKEYKDSIYVYSNLKPKNADSYHGSIIVMLSDGSVLYEIQEVIFKSLIPIKHSLKIEYPNDELYKVHLQSKDSQIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKNQRLFRFVFETIKENGILNSLEENDDAYFEFNELVIKSSKIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCSYLRKKYQMISHVIIHSIKEIINNNIIIRILEFGGGTASLSVEVIGEIVALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGLNVIYRSLTIDESLLENQAIKPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFIEPPYKSVLIDSIIGSFEQWWSFTDTDIRKDRCGMSQQSWYQLLKTCNFKDILMSKECIFVGSVIHAQKPPISLLNSQPKHDNIIIYGGGGNLSFVENIKLDSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNYKQITLEYIEINQRLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLHTLDFDYDSTQNYINSKNNKMVQFINILVDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNNNNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNFKNIQLKPSNISHNEASSIPIDYLTSFMSLFNVGSLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVDLDETKQYLLDRYGDFITGIYSNTDKSYVTEIKNELIKLGSKKKGVDLILNTLPSDFMDSNFELLTKSGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFQLSLIQKNKIQKCLYEISHAIENGELKTIPIKEFTNLNIKDAIKYITNGNIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAVNLHNQSIKRNWKLINFVMASSALSLIGSTDQCTYACANLLLDSFSKYRESLGLPSACINLGSIESTGFVSKNESISEFTDGIGYVPTPINLVLGLLDLQIQNAGKFTNSMLSNLISSKFKNIQQTSLFLKFDYLMNLNDNSEQTKKENIGNKNIDELFIEKVSELFSTDQSRINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIKQLQNNTINISIKMILNSLMKNNQI", "length": 2514 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G110-1", "protein_name": "Acyl-coenzyme A oxidase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKNRIEIIKKHLEVNNSQTTNNKDEVLEKELFNSIDTNINVGELKLLIDSVEESKYKDETREFIRNHPKFKENFIGLDMATYRQLVLEQCAAIANRGLIHFTDIKNNLHRYIGALEMFALYNNNILTKLSVQYTLFGGPIIFLGTSRHEKYIEDANTLKTMGCFAMTEIGHGSNVRGIETTAHYDKQTKEFIIHSPTPTSEKFWIGCAYLHATYAVVFANLIIDGTNYGIHAFIVPLRCPKSGAIMKGITIKDCGHKLGLNGIDNGQIRFDQVRIPRENLLNKYSDVSEDGVYKSQFNTPIKNFAATMSPFIVGRMAITKGCSGAAKTSLSIAIEFSHIRKQFGPSSNKELPLITLSSQQRRLMAPLARTILFDLYIQRLTNELCQEKLPASIHAHCSGIKAVYSWFCVAALQTCREACGGQGYRSANRIAEFKNDCDIICTYEGDNTVLMQQLAKYLLGVKQKQTNTTTNRIYLDGEDAKSLFFNFSNINQLFETREEMRLAELKQIIDNSKESAYFAFNNAIPWAVKLGFAHMTKIVFQNSINTLKLKNVKPLTHLIMLDALVSIEEDLGWFVSNHLISPNVAQSIPFLIQDLCFEVTKVSKQIIASFDIPENCKPSSKDLISDLF", "length": 629 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G138-1", "protein_name": "Probable polyketide synthase 21", "gene_name": "pks21", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLENKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSIAMGFQSIQNGTSNLSIVGGVSLLLDPYISKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSKTSTPSKPLLIGSLKSNIGHSEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNNNEKPVSMVINNFGVTGSNCCLILSQFIEQSINQNGNGHSYPAESQQQQQQRFLIPFSANSVKSLKNYEDLIINDIKISTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTNNDKSSNITIKRNQPLVVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLNLKENNIFCAFLGSLSSFHTSSQHSTKNEILPLDIPSKQSRIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDVNFKCQFNHNDDDVSSIRNSKVNISLPNYQFDEQHYWKVDINFEQYRLNGPNVFNSLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNQDIIINNLEFLAPFVLKENVKHTLQTNVYQLGNTDYRVTFNIKDNKTNQWVQTCTGNFQLISLKDNNNDHSSKYDINQLLSECNFTTLSKQEVYKHSRSITGITHLGAFQGIEELYFGNDCIISKIQVNTENFDIDGKPVYQTYDKSFFNTALLDSCSQTIVGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLESDSYKSSVLVLLEDGTKLLEMDCISLHSTLPLLNSLLINNPTTELFTNNLQCKDSLVNILSIDNNQTFSSISSSNTVTEIIKQTIKPIINEKIVFRILQSFSDLELSKQIIETLNQIFDDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDGDDETIIKSIFNILSSNGLLLIIGDDIGDKYNIDSLINLGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKESKYTNEFMKLISNNHISCKQTIISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGTARYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNQIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISNENQNCEFKVGDNVFGIACDTTASHVIADVLYVSHKPENISHVEAASLPVIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIELMHINKKVVSRLLKSISNALNENKLKPIPITTFQIEDVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKSVDVGDPIEMRKSINQILLENPNIDNIDSIFHYAFAQITKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCSYVSANLVLDSLSRYRKSIGLPSTCTNWGAIKSAGFVSRNELVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKNSNLIVSKFNYDSIKKLSSETSTFQRLDFILNSIKEKDNDSNGGENSVSESIQTKILNKISELLSIEQSKINTDIRLSDYGADSLTSVQLKNFIDKDIKSNVITLQQLQNNTIDMNIQTILEQIKKLDSNETKGKSKNIIKKDSAPTLDYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKIKVIVGNLASPLLGLSKLDFDYISNQINLIINSGADINLASNYEESKVVNIGGFIELIKLSTTGDYQKPIVGFSSVSVFFNASNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLLREVAKRGIPSMLIRPPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPKIDKNILTSPIGWISLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSAMNPSFSFLEKQYGCEMVEYEQWKNIINQSKILSCVKLKTFHSLDDLYNIYNLGNGFGVSKKTKELLQSMNSYEGGMVNEKMIQNHINYIFKN", "length": 2779 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G149-1", "protein_name": "Transmembrane protein 184F", "gene_name": "tmem184F", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLSHINIIYIIWILLFFFTCLISFFLVNRHLVNYSSPNVQKNVVRIVMFLPLNSGLSILSSIFPGIAIFNSLVRNCYMAFTAHCFFSMMTNSIGEKNMLDLFESQGKMKFLCCKVMKLNRKLFNTLRFGSIQFFIVKIFCSIATITCISISEEVHSILNVQSFAPYEFLISLVASIFCTISLSIFLAISKEKLSQYWPMTKYRIMIFIFFIEQFEYLFFALIFLRGPFFLGFKNSFDQTIFILHFTVVVTMFLFSIVYLFIYSYKNYRNKASNEPLVGRNFKDSFGLLNYLDVLNPKDLFIDFASIFKTNNNKFKELVEENGDKKPKKNIEDQNQENSNDQPLSIQMA", "length": 348 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0G188-1", "protein_name": "GATA zinc finger domain-containing protein 16", "gene_name": "gtaP", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSYQIQNQPYQQIQNTHPSFQQVQPMQVPHLQQQQQHQTMIAQQQHTPPQQHTPPQMNMIQQHTQPMLSQPQISLQMQPPSPILASQQQQQHMQSSPILASSNLTNSNNASQTTLPIITSKLLLKKEPIDQEVVNSTHKTTTTNNKPPKQSKRKEKERLEEEKQTVAQQQQYQPPFIPLASNESNSDNPFKGSHAYGVSTTPYGNSQFNNNNNNNNNNNNNNNNSNNNSNNNNGNNNINNNNNNSNNNNNNNSNNNNNNSNNNNGNNNNNNNNNNNNNNNNHNTNNNNSNSNNNNNNGYQQDKKDDYSMMIWSEVGRKINILIRTTSKATKGTPISTQEIAEAIGASNGVTADLVELIKSINDPTYVRKLPPSSISNTPTMGSQSGGMVYNSSPMLSPSTMSPILQHGNYQMGGDMYFGGNNQFSGDKQSALNNVKNSKGGNTNNSGGGSSSGGTNDTQAKKPARRRKMRYGGTELSCHTCGVTNTPEWRRGPNGAKTLCNACGLAWAKSVKSEKQKELLANSTGVNITEPKKAQKRKKESSDNNNNNNNSSDSNKVLKSDDGSNNTNLTNDDDNGYPSSPNSSNSTSPSSHNINNNNNNNNNNNNNNNNNNNNNNNNNNNNIGNNNNNNINNNNTTNSITTPTTTPFPTTIPAMQIVSQLPVMVPQTQQQPHMSGNIISFQALHQNSGYQHYK", "length": 695 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "B0R191-1", "protein_name": "C-X-C motif chemokine 11-6", "gene_name": "cxcl11.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTLAAFLLLSCLIAGEVNGQDRSSRARCFCVDKGLNMVLLKNLDKVEIFPPSPSCNKHEIVVTLKNGAGQKCLNPDSKFTKNVVLKAIGKRMQQSVPHSTTTGTVKSSMTSSTSAPTAFK", "length": 121 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1AV09-1", "protein_name": "Leucine zipper protein 4", "gene_name": "Luzp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANHEDEIRQLRYLEAANSEEEYNEENDIQSESSRGQAFFPGHPRGRGHRRDSRGRNGHFFRQRFSANHPLLHLTRQVNLESLTRRNGNQSEERQLQQERIQLFFRSLHGLSQSHDHHIGRSHGHYSRRSRNRFRRAPVHSERSHVYSGRTNNYTDRPHHDLSDRPHNQLSVRPHPDLSGRPLHDYSGRPHQNHAVRLQHGHSDRYHLTHTERVLPNNSGIDHPGHTERDNQVQRGRAHDNQSGLAHHNHDGRSHHDHSGRAYHGHARRAHNNQSWRSDNNQSWRDLNQSWRGQNNQSQRGHDNQSQRGHDNQSRRGHDNQSQRGHDNQSQRGHNDQSWRAHNIRSRRDRYHTSLRSSSIQSWMLHERERYHGPRGRNGPRDASPPGSEPEIDRSSAIRERTDYLWVQEHRRNETVELNVGLEDGYSSAEESDESLDRLTCRSMLDTLY", "length": 449 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AY40-1", "protein_name": "SSX member B8", "gene_name": "Ssxb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METVSFCEKVPMEVLYEPKNICKAFQDISTYFSDEEWGKLTQWQKSAYVYMKRNYIRMTDLGVTVNQPVFMSGKEQDKQSLVEGIEVHDSEDECFEGSFGVTPIKQMKLTPVTISIHNVEGSLASGENNSNLAETSGIQVNVWSHRLRERKYRVIYEEISDPEEEEDDDY", "length": 170 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AYI3-1", "protein_name": "Predicted gene 13272", "gene_name": "Gm13287", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPVHLFLVGGVMLSCSPASSLDSGKSGSLHLERSETARFLAELRSVPGHQCLRDRTDFPCPWKEGTNITPMTLGETTSCYSQTLRQVLHLFDTEASRAAWHERALDQLLSSLWRELQVLKRPREQGQSCPLPFALAIRTYFRGFFRYLKAKAHSACSWEIVRVQLQVDLPAFPLSARRGPR", "length": 182 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1AZM5-1", "protein_name": "Predicted gene 12886", "gene_name": "Gm12886", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLPCSLWLLSVCLLSWCCDAKLPVALDPESESVPKPPVLKTATEIAAIVVFMKTSNETPKSGTYGQSLQDGKNKIKDVEKEVLDACSQLCQSLAQDPNLHHGYILRAYFKEHQFLCCF", "length": 119 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B1B0R2-1", "protein_name": "Spindlin family, member 2D", "gene_name": "Spin2d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSKLTKKRAGRKRQRSRSPALPKRNIVGCRISHKWKEGDEHITQWNGTVLDQVPVNPSLYLVKYDGIDSVHALELYKDKRVLSLKVISKRVVSSGVTDSSFADAIVGKEVNHLFEGEHGSKEEWRGMVLSQAPILDNSFYITYERDPILYTYQLLDDFKEGDLQIMEGFSDPPSLDIDLELVDGLIGKHVEYTNDDGSKRDGLIIYQIETKPRVYLVKYEDDVHIHVTHLEKEL", "length": 236 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "B4F7F0-1", "protein_name": "Claudin", "gene_name": "Cldn6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASTGLQILGIVLTLLGWVNALVSCALPMWKVTAFIGNSIVVAQMVWEGLWMSCVVQSTGQMQCKVYDSLLALPQDLQAARALCVITLLIVLLGLLLYLAGAKCTTCVEDKNSKSRLVLISGVIFVISGVLTLIPICWTAHAIIQDFYNPLVADAQKRELGASLYLGWAASGLLLIGGGLLCCACSSGGTQGPSHYVARYSSPVPHSRGPSEYPSKNYV", "length": 219 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B7ZW38-1", "protein_name": "Heterogeneous nuclear ribonucleoprotein C-like 3", "gene_name": "HNRNPCL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASNVTNKMDPHSMNSRVFIGNLNTLVVKKSDVEAIFSKYGKIAGCSVHKGFAFVQYDKEKNARAAVAGEDGRMIASQVVDINLAAEPKVNRGNAGVKRSAAEMYGSSFDLDYNLQRDYYGGMYSFPARVPPPPPIALAVVPSKRQRISGNTSRRGKSGFNSKSGKRGSSKSGKLKGDDLQAIKQELTQIKQKVDSLLENLEKIEKEHCKQGVEVKNAKSEEEQTSSSSKKDKTHVKMESEGGADDSVEEGDLLCDDDNEDQGDNQLELIKDDEKGAEEGEDDRDRANGQDDS", "length": 293 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JKF6-1", "protein_name": "BTB domain containing 35, family member 13", "gene_name": "Btbd35f13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRFLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGAINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYVLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD1-1", "protein_name": "Spermatogenesis-associated protein 31F1B", "gene_name": "Spata31f1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD2-1", "protein_name": "Spermatogenesis-associated protein 31F1C", "gene_name": "Spata31f1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HKD3-1", "protein_name": "Spermatogenesis-associated protein 31F1D", "gene_name": "Spata31f1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTMCFLWDTECPLYVYFCFFIIVLIVWQVRQNYQGLKCENRRSCCRRHQKVRQRAKDAASRARRLSREEDEKPCELLSIMKSQSWVPKQGNVRQLLCLDPSCQICEATTLEIRQLLQSKKSQISPALLGLPQRAACLEMPISSESFEWNQDFYSRYSTNSPVVPGNQTLTQLTEELTESTNADGVLLCWTDPLQIGQEFHLADMPMASETLVSPGLEEPVVLMNEEDTVHSNLNYIQQLQDHEALNSQIPFQTLTPQLTVTHPMAVSIVTDAPQPFLSPEVLRLLEIHVKKLMHFQRWGLPRRVEESLKQFMPNPPVYLPPEHNQPVSFILNTSSQDCVHRFEGISPETWYSYMDGQPIQTFWVSEWSSGDQGQRLSCKPIPSPVEKPLLTPDYELLHDLCLSPEGQVDGSQSNLQKKFTQLFCGLPSMHSESLGSTFLCTQGVSKNTLKPPYKEPHFLKVSPPIPLPEAAPPPSSTSPNESLDEPQRAQIGGVPFLTLSECKTLEWHLLQRQLQLQWGLPAVIARPPRVQSHTQYKHKPWNKAKPRETLKFFGPGKPFSALTRELFFIPQHARRLLEFHLQKRLIHLRWGLPQRIQRSINMLLSSTDLQSLPCGGSRLPNVSISQPGKPEAYGSGDTFLPTAGKGTTPMPHLFAKAQEMLKSHDTKCEQIREGKVPACVQSAWKGRIPGDLAAGTLFPNIPQGQPLELQAENNPDLHQEAVSWKPMDLDQEAQAFSGVFIEHCRRPQALSEETIKKLETTLRHKYLAFLSGLQALYCMAPTKATSPTVDQSVITTMPWSVKSPQKPLSQKSPLEALCLSGLEPCTQDDKETSANIAEEFQHGAQGHGRTEKVPPERQPLLNRPYSLDTEIMERVSFYLKRKALDIKLGISLKESVFQEPTATDLESESVQEPLGSPRESTLLQGPPTLCHVPVAPDPDKVCLKQPATAVQVVFQEQNQPSSRAVPHRSARQGSQVHRNMMEAQVHYVQMGTGGEMLNLGEPFSTESQSPGKSKSGYVPTVAGKRKIPGKPKVVGDLGEGDAGLGFSLVSLKTRQDGEQEKRLLHRQLQGSSLQAQTFHLEGACPHSPQESPELQFADPPPEVFMETDSEQDMEDSQSKESIVPEPARTAKAPQPMLSRASQGLPFPRSPTQRKPSQGQPGPGHVPPGHATPASPYTRPSRLPEAGLKNKMKLFFHSIKLKMKSKAHTEPSTVSTPGKVAKTSKENIDRGLPQAKSPTKKTKPEDFRGPKAQFSVVGPCLTPSYILDSKFWPRPRRVGSVSVLGHSYHCPRHCPRLAYANQQRNPP", "length": 1308 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "C0HLM6-1", "protein_name": "Small integral membrane protein 20", "gene_name": "Smim20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARNLRTALIFGGFISMVGAAFYPIYFRPLLRLEEYQKEQAVNRAGIVQEDVQPPGLKVWSDPFGRK", "length": 69 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C7G009-1", "protein_name": "Thioredoxin fold domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLILNGNWLVKFGAGWSGHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEYESICIKYNIIGYPSLVFFDEGEIKHYRGPRLFENFKEAIDKHLNKEFVAFSQNQPSKIIVITNENLDLLLTGNWLVKFGAAWSLHCKKLQPVLENLAQHYNSDNENSKVKVAQVHCEEDNSICKKYNITGYPSLVFFNEGQIKHYTGPRQFENFKEAIDKHFKYGVKWSGHCKKFQPVLENLAQHYNSDIENSKIKVAQVHCEGDDSICKKYNITGYPSLVFFDEGETKPYRGLREFDKIKEATDKHFK", "length": 303 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G010-1", "protein_name": "Calcineurin-like phosphoesterase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLKIKFSIISLFILKLVISKPILKFNNNNQFKIIQFTDLHYGSEPVDDIDTIFSQVNILDYEKPDLVILSGDMVTGYEEQFEDDDRNYWKYWNVFTRPFVERNIPWAITFGNHDGEGALSTNEILKIDQTFNLSLSQSNPVEMHGIANYVLKISSSNSLKSEPASLVYIFDSSTKGCSKLDWGCVHQDQVDWFKNTSKSFNKTDSIAFVHIPPVEIIDLWNNYPVYGNYSETSCCFDNDYGDFVSSLVESGDVHGLYFGHDHENDFHGDYKGVDLGYGRKSGAGSYSSKKPLGARVFQLTESPFTLSTWIREEDGNIVSQVIHPPSEFDRKPLQCKMKDKYSKKELIAIKVIGGFLIFLGIVVVGLIGFFGFKHYKKFKKQTLEMQNLV", "length": 390 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C7G064-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKDEKQFQQFPNKGRTVQANTDLPKGSTVFRCAPFASSIEDSDKLATEKYCGFCLQRIPKSDSKECLCKNCKLYSVCKSCRSINESAVEPFQIIIKSTFHLGSDTRDMRLLLRIIANIANGKQGMQTPIDDYQDFMGLTSTLDKVDKEHMTKFKRGVTSISSLISSVRGVGYLKNTITIHEILECFSSVLTNAHQFSYATSKEIGRGVCPTGYFNHSCMPNTTWSLDDQGMLLFSTSSNVKKGDELSLGYLANEYPLKNRRRELLDGYYFFCQCPLCEFQSNLSGYLCEKCKEPLLNDSIVYHEPSLTNPLDTGIGLIKHLRKMIDFRQQSVEFKKMFSSEQLSNILQKGVPKHIQSVFNCDASDNEELQQIVEISERSIKSLPLINGEPIDFYPLSDRNYYEYFKQLKNSKISSPEELQRIKDKILSLINPTIYNSFKDKIDKRLLI", "length": 449 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "C9JPN9-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 12", "gene_name": "USP17L12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLKLSSTTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3YTW8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r258", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSIHQFVILVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAESRATQTILIVVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNL", "length": 314 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTX5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r259", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY1-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLDFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YTY2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r138", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YXI8-1", "protein_name": "Predicted gene 10377", "gene_name": "Gm10376", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQAGSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQNNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKILCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAVMSNPCA", "length": 184 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYI9-1", "protein_name": "Predicted gene 7347", "gene_name": "Gm7347", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YYY1-1", "protein_name": "Secretoglobin, family 2B, member 7", "gene_name": "Scgb2b7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACFPFFEAYASVLSGSRVWLYQELQAFDATAEEKVALEKIQDCYSEESIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z236-1", "protein_name": "Predicted gene 3676", "gene_name": "Gm3676", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGSQTVSFRKASPQTPNIDENEKRIKRLEKLKRDLQNIKNERDILQGILAKYKDLNDRTNFETFMLEMQHNQMMTDLKRMSQDISEALYKCQHLTKENQLYCCRNCHLLIESNLIQHKVRMLWKENRQLLRKQIALEECNIKTKTLCKEGSQKIKDEYSRQAAGKQIIVVPGSKEEAAMSNPCA", "length": 184 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z8D1-1", "protein_name": "SIGLEC family like 1", "gene_name": "Siglecl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLWGLRSLLLLHLGFLSPVLVDTKKTAVEDGLCSTVPCVIEFSKAPLRKPMIVSYRLNENISFHAGTSQPRGPVADLSTEEVEYCILLTHNMLGRKNMTYSLYVGLGAQKDLTQKQELHIPGSSMAGEPVSLTCTIHSTCQESKALFLSWKGPIMSSSTTVPINPSSALAIDPKPEDQDTTLRCHLKLSLDNLSSSKVVKLQLVSPARLLNYSCLLKRTLTCSCSFHGIPTPSVQWWVGRTPVSVNSIDAILHMTSTTLESWTNSTIHLMWEPEIIKSLRCEGKNQYGVHASGIFLIPDKSSVSSVFLRGLIQGIVYGAIASALFFFFLVVLGMKILNWWEENQTCKNEEAPTLKKPVWGGAKPAEVGS", "length": 369 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z8T0-1", "protein_name": "High mobility group nucleosomal binding domain 2, pseudo 3", "gene_name": "AABR07053402.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKRKAERDAQGDEAKAKDEPQRRSARLSAKPAPSKPKKAPAKKREKIPKRKERKADAGKDANNPAENRDAKTGQAQKAEGAGVAK", "length": 86 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9U8-1", "protein_name": "S100 calcium binding protein A7 like 2", "gene_name": "S100a7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSSEQEVMKLFDLFQNYHVRRTDKLDVQETKRVLREFFPNFMKALNASGIKILNDLEKEITLDEIWDMIGRMAMAYNKKNSNALKD", "length": 91 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3Z9Y3-1", "protein_name": "Ceramide kinase", "gene_name": "Cerk", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAMGAAEPLQSVLWVKQQRCAVSLEPARALLRWWRSPEPGPSAPDPDAYSVPVSEIIAVEEKEVHQKQSSNGRWHRMENPFAFTVHCVKRARHHRWKWARVTFWSADEQLCQLWLQTLRELLENLTSRPKHLLVFINPFGGKGQGKHIYEKKVAPLFTLASITTEIIITEHANQAKETLYEINTDSYDGIVCVGGDGMFSEVLHGVIGKTQQSAGVDPNHPRAVLVPSTLRIGIIPAGSTDCVCYSTVGTNDAETSALHIIIGDSLAIDVSSVHHNSTLLRYSVSLLGYGFYGDLIKDSEKKRWMGLVRYDFSGLKAFLSHQYYEGTVSFLPAQHTVGSPRDQKPCRAGCSVCRQSKRQLEEEQKKALYGLENAEEVEEWQVVCGKFLAINSTNMSCACPRSPGGLSPFAHLGDGSSDLILIRKCSRFNFLRFLIRHTNQEDQFGFTFVEVYRVKKFQFTSKHVEDDDNDLKELEKQKFGQICKDNPPCACPTSRSSWNCDGEVLHSPAIEVRVHCQLVRLFARGIEEES", "length": 531 }, "evidence": [ { "id": "HGNC:19256", "url": "https://alliancegenome.org/gene/HGNC:19256#orthology", "database": "AGR" }, { "id": "MGI:2386052", "url": "https://alliancegenome.org/gene/MGI:2386052#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZAM9-1", "protein_name": "Olfactory receptor", "gene_name": "Or4f60b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKVNYSVTSEFVFLGFTNSWDIQLLLFLVSSMFYVACIMGNCLIIFTVASDTHLHSPMYFLLANLSFIDVGISSATSPKMISDLLKKHKVISFRGCVIQIFFNQAIGGAEMVLLIAMAFDRYVAICKPLHYLTMMSPQMCLFFLITAWVVGLMHSVIQLIFIVNLPLCGPNILDSFFCDLPQFIKLACMNTYRLELLVSISSGFMSLVSFFLLSISYIVIILTVLKHSSSGAYKALSTLSAHVTVVVLFFGPAIFFYIWPSSTHLDKFLVLFDAVVTPFLNPVIYTLRNKEMKRAMRRVFRHLMGYRQIS", "length": 311 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZC26-1", "protein_name": "Ferritin", "gene_name": "Fthl17fl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEDAINNHIRLLLQASYSYLSMAFYFDRDDVALGNFKRFFLSKSHNCKASAEMFVFMQNKRGGHVFLPSIAKPDRESWHGGLRAMECAFRMEMTINQSLLNMHELAKGKDDAHLCDFLGQHCLDQQVHVLKKMGGYLTNLRQMGAPEQGLAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCM9-1", "protein_name": "Dynein axonemal assembly factor 3", "gene_name": "Dnaaf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTPAGSGNGFGTVSWWGLSPALDLQAESPPVDPDSQSKTEHKIPELDALLLGSVDGRHMLRTLARAMLWPLRRFNFYVLENNLEAVARHMLIFSLALEEPEKMGLQERSETFLELWGNALLRPSVAAFLRAQASHLSNLVPEPDRLEELLPWLSLRPLKFRERDALEAVFRFWSGGEKGPEVFPMSRLWDSRLRHYLGSRYDARRGVADWDLRMKLHDRGAQVIHFHEFRRWRDTGVAFELRDLSAYHVPNRTMASGRLLSHRGERVAARGYWGDIATGPFVAFGIEADDKSLLRTSNGQPVKTASEITQHNVTELFRDVAAWRGPRAIKGNVEETKSPEPDAPAQEPFTIHFLPLDSSQTLHHKTCYRGRFQLLYVSCGMIHLLSPELGACVAPGGNLVVELARYLVDLRPKELKAFSDRVVEIAQAAGFAPHTGTKPSETFARFYKLGDSTRGGGDSAVESGPVPSKVLAPTPESINPPQADQAPSLEVMSPPKVDQTPPLEAMSPPEADQAPPLEAMSPPRADQIPPLEAMSPLQAEVVLPLEAISPPQADLAPPPEVISPVQEALAMSSAIAPLKHVT", "length": 583 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZCW3-1", "protein_name": "SPATA31 subfamily E, member 1", "gene_name": "Spata31e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "METFLLLMNSISDFWMSSSSMSTVMDMIFAILCGVGFFFLLIPFLKEYPGSPPPGSKKNISEVVKRRQSKDRKKSVTVDGCRDSQKNSLDIQHDLQTMESPIQHLLLDSSPHPFWNSKEKLNQLSLPQLFSYLKVLEALIQQKFNQLLLGLSSVLSESVVATAWVSREPSSGERKTVRFSDSLGFDQALPLAKGPPQRCLDQPLPHQLVTPSLVGMTEIQEQENLPNSISYQTPSIFQSRARGTAYPTTATGIQVPLPTTNEPCHPGLNWKDIPSCKVQNCQGASSQPTESLARCTLPTKNTRSASIPPEHYLMVHHHEQPQHEEKAINLGEQQRTHARFLPSKEPAQLQGDSPPNSNGYGKNWPELNQPAQPSTLNSKTYKWNQMMGPVPTGMLLKKVIAKYGIPNTIKKDLKLRVKDLLCTSSSTPGESLETKNLTLRTDEHSMNTTENLSFLDPKTTMMKSNIMQLPMKHRQLPCDSKAEPYTKAAFILENLHHQDPGGIRVETASSARLRSPLFEQSPPEVQKTQSSPPPIDSHGHSRSHPDQWQRYQSVQPHALCSQAQPQQSRSIQGTGRSILQPNISVWMSKHERWMRSEDVASGHTSWSSRTVGYRDRVSPSVAKQTNILKIKEESPHVWRANLGSGEITNEQALNNSNEDFEPIEAKRSQGHLQMPTQQNTGYLHLKTEEYSNNDLKVNKQPQAWSVSHHADGSNTVHHAMVKLPSQHSLPSLQNGWQDPKTSQGLGDLLMNRDQSVETQFRVHKDKTEATNDSVFHPSEKRPSNLKYGGISQGERLGRVKSSISSFTQLKDSAKTESKSSPNIGGKREAPSKSSLKFIWNGAQYENLSTKLKGQRDSLKKDIPPPVTEQTQEVVHRINVIYSTAVELQSLMDSLVHKLVKTVGEPSELTRKHMTKVQEYKMESLPFQLGSSSQPSKGLHDPNKSRSVRRMSDDHTSPKEPNNHTFTYRGNRDKMQAGVDVQRVCYQHLDKVKIGFGQHSTPMRNGNPCFHKKAGDKQESSLADQSTGDADQTKPKNEIVGSPHRIPERHNQSSRYREIRDNQEPSVDHKAIDPHQNTKKGMGYSQLMSPKENHPVKISGTAAQGASDPEEIRTKSGKECSPHRSPKMHDHSLRHREVRDKPQPGINTQRAYDQHLNSPKKRMTSENLLTPKGTNHPCWHRVTGDKQQSSLSDQRACDPEQMRRSGMSSYPQRSPKVYHLSCSSEKIGEKLLPLVNDQRTHDKHPNSVKTRGCDNLPTPKGSNHPQGYRVIEDKQQLGLAYRRTCDPGQIKKSGMGKGPCKDTEECNLLYRYKIIGNKQQPGIVHRACDRHQSSKEGMGQGQPMNPKVCHSAKHRRTGGQDQSGVAAQGASNPR", "length": 1373 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDD6-1", "protein_name": "Synaptonemal complex central element protein 3", "gene_name": "Syce3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADSDPGERSYDNMLKMLSDLNKDLERLLEEMEKISVQATWMAYDMVVMRTNPTLAESMRRLEDAFLNCKEEMEKNWQELLTETKRKQ", "length": 88 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDJ1-1", "protein_name": "Olfactory receptor", "gene_name": "Or13c3f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDMDKNNQTFVSEFLLLGLSGYPKTEILYFVIVLVMYLVILTGNGVLIIASIFDSHLHTPMYFFLGNLSFLDICYTTSSVPSTLVSLISKKRNISFSGCTVQMFVGFAMGSTECLLLGMMAFDRYVAICNPLRYSVIMSKEVYVSMASASWFSGGINSVVQTSLAMRLPFCGNNVINHFTCEVLAVLKLACADISLNIVTMVISNMAFLVLPLLLIFFSYVFILYTILRMNSASGRRKAFSTCSAHLTVVVIFYGTIFSMYAKPKSQDLTGKDKFQTSDKIISLFYGVVTPMLNPIIYSLRNKDVKAAVKYILKQKYIP", "length": 320 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDT4-1", "protein_name": "Transmembrane protein 92-like", "gene_name": "LOC100364194", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQEAWVLDALTVIFGLLFSLQGVSSNKTIYKCEDIHCPKGFRCCDNECCLERKIWNTDNEPFRILFIILLVMLPLLCICGLVRRFCPKCRELQHEVRTADHQSPPDPPSIAPLESIWVTSLDPPPPYSQVVQKSTPTEPPPPYSLRPEDSTCPMRETSHETL", "length": 162 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFJ9-1", "protein_name": "Family with sequence similarity 24 member B", "gene_name": "Fam24b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSSFDLRTIIMIVIGSGILAAMFLLTGVVLCLYSKIARALNPSGTGKELDDQLCSDPCKTTQDQIIRVNSLNADTCRPFHGSTIGLENCQPLQCFSACGTYEGANSLTPCLCNTKEGL", "length": 119 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZFW5-1", "protein_name": "Transmembrane protein 107", "gene_name": "Tmem107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRISGLVPSRFLTLLAHLVIVITLFWSRESNIQACLPLKFTPEEYEKQDNQLVAALCLTLGLFAVELAGFLSGVSMFNSTQSLLSIAAHCSASVALSFFIFERWECTTYWYIFAFCSAFPAVTETALFIAVFGLKKKPF", "length": 140 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZG05-1", "protein_name": "40S ribosomal protein S12", "gene_name": "LOC120100003", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEEGIAAGGVMDINTALQEVPKTALIHDGLARGICEAAKALDKRQGHLCVLASNYDEPMYVKLVAALCAEHQINLIKVDDNKKLGEWVGLCKIDREGKPRKVVGCSCVVVKDYGKESQAKDVIEEYFEYKK", "length": 132 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGM7-1", "protein_name": "Peptidase inhibitor 16", "gene_name": "Pi16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNCRVSWMPQHSSAAVSGICPPQEGPWSSYSLWPEPPLLREKEAVAKDSRGVDSTLVQTQGTQPSWRHCVSWAGPPDTAPAAPPQPGWCLCGKDFKSSRQTPDRERQRGLATMHSSCSPWVMLPQLPLLLLLLLLLLTATGPATALTEDEKQTMVELHNHYRAQVSPPASDMLQMRWDDELAAFAKAYAQKCVWGHNKERGRRGENLFAITDEGMDVPLAVGNWHEEHEYYNLSTATCDPGQMCGHYTQVVWSKTERIGCGSHFCETLQGVEEANIHLLVCNYEPPGNVKGRKPYQEGTPCSQCPLGYSCVNSLCEPERKPEKAQDSPPRVTEVPGSRETGIPSLATSESLHFSSVTKVSDSLATEPSPAVETKAPPSLATEGPSSMATEAQSFLTEVPSVSATHIQPSLDEGPVNFLTSTHIPVPKSTDKEASSKSRAASVSPEKSLYPKMSPTETGESPPQIQEEAEPKAELPEREDELPEAEVELPEAEAELPEAKAELPVSSEALVPVLPAQERGGPKASLEHSSYPVPTYLPNFPSASGNATGGRTLALQSSRTGAEDPEKASWDSKNSAPVWGPFPGLLLPLLLLAGIF", "length": 596 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZGX2-1", "protein_name": "C-type lectin domain family 2, member M", "gene_name": "Clec2m", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQTESSLRLSQSSHHRLTFDLKKVVTLWILVIGVIAVLLWGFFSFPKKFTVTRQTKNEVCSDGVKICLHGWNKLNRNCFTHFSHANSWFTAKETCKFHDATLAVFNDQTELDIVMKQMEDIQTFWIGLYKKDFRGPWVWTNGSKYNNWYEVQDYGHCAFLHKSGIDSTNCNDLKEYICTQEGHCP", "length": 185 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZIZ8-1", "protein_name": "Ferritin", "gene_name": "RGD1560203", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEASSQVRQNYDRCCEEAVNTHIRLLLQASYSYLSMAFYFDRDDVALENFKRFFLSKSHDCKASVEMFVFMQNKRGGHVFLPSIAKPDRKSWQGGFRAMECAFRMEMTINQSLLNLHELAKGKGDAHLCNFLGQHCLDQQVHVLKKIGGYLTNLRQMGAPEQALAEYLFDKLSLS", "length": 176 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKK4-1", "protein_name": "Zinc finger protein 869", "gene_name": "Zfp869", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTPIVGLSSPDQGLVSFEDLVVHFTQDEWDLLEASQKSLYGDVMLETFRNLTAVGYEWEDEAIEDHCEEPEVNLRDIVSHSEYTHEYEHKEYEEKPPDANFLTSVEGCVETKTSSGPSVCEVCLKTFGLYHLTYNGHHNYDYKELRGSQTEENDCEGNSCDKTSGSLQKEDKIHTGKKLYVCQECGKAFRYPSALQLHERIHTGEKPYECKDCGKAFRGLSALHLHERIHTGEKPYECKQCGRAFTYLSALQLHERIHTEERPCECKQCGKTFRYSRALKLHERIHTGEKPYECKQCGKFFRSHRTLKLHKRIHTGEKPYECKECGKAFRWLTSLKLHEKIHTGEKPYECQECGKAFRCQASYHRHKITHGGETLYECKECGKSFIYPSLLQVHERTHTGEKPFECKLCGKAFRCQSSLRLHERTHTGEKPYECKHCGKAFSSYNYLRFHERSHTGEKPYECKECGKTFTHRSYLRSHERRHTGEKPYQCIQCGRSFSRHSSFKRHQSVHGESPYEQYLIPLSPFSSKE", "length": 530 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKM3-1", "protein_name": "Protein GPR15LG", "gene_name": "Gpr15lg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRLLTLSGLFFMLFLCLCVLSSEGRKRPAKFPKLRPCCHLSPRSKPITWKGNHTRPCRPCRKLESNSWVVPGALPQI", "length": 77 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZL22-1", "protein_name": "Olfactory receptor", "gene_name": "Or1x2b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSKWGENETGVIEFLLLGITNDPQQQRILFWAFLCMYLVTVAGNTLIFLAISSDPHLHTPMYFFLANLSFDDVCFTTNIIPRLLAGHVSGTETISYAYCLTQMYFLISFGNVDTFLLAAMALDRFVAICYPLQYHTIITPRLCVGLASVVWISSGLIALVHTLLMSRLTFCSSIPEISHFYCDAYLLMKLACSDTRINQLVFLGAVVFFVAPCILIVFSYVRIAMAVFQIPSAKGRHKAFSTCSSHLTVVILFYGTVLGIYIRPPDSFSTQDTVATIMFTVVTPMLNPFIYSLRNKDMKETVTRLLHRGSKSS", "length": 313 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLG9-1", "protein_name": "N-terminal Ras-GEF domain-containing protein", "gene_name": "AABR07047293.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSCCVWTTEGSGLKKDKNEGQGGTWKFMLLSCLQCLWPFAQKEIDLTRDNQAQDHEDQGEHEYAPQVVTEPCRESRISADMVENLVNRLVSSLQGGDPFFIPAFLYGYRQFTTTQHVLDRLLKRFAYFYLGCEEDEQIKSSLCCFLDTWIDQYPEEFSQTILKKLKTYLTVNMPSSDLNLRVHMLLKELRQESNESEGKDDDSVSLPVTLLYKTASAADLSSSVEVGSHTSGDLDIEVWFPSQKVQPEPAYPHETETPQSTIKVISWD", "length": 269 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZMT2-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3", "gene_name": "Ndufa3-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGRSSDFFKNAQAKEPVLVVSFSVWGLAVILPMISPYIKYAGVISKATPYNCPVPVRDNGNVPGVPSQPQERLSPSLERLKNL", "length": 84 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNA3-1", "protein_name": "60S ribosomal protein L7a", "gene_name": "AABR07049918.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQETKNVVNPLFEKRSKNFGIGQDIQPKRDLTRFVKWPHYIRLQWQRAILYKQVKVPPAINQFLQALVRQTVTQLLKLAHKYRPETKQEKKQRLLAHAEKKAAGKGDVPTERPPVLRAGVNTVTTLVENKKAQLVVTAHDVDPIELVVFLPALCRKMGVPYCIIRGKARLGRLVHRKTCTTVAFTQVNSKDKGALAKLVEAIRTNYDDRYDEIRCHWGGNVLGPKSVARIAKLEKVKAKEFATKLG", "length": 266 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNR1-1", "protein_name": "Elongin-B", "gene_name": "Elobl9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVFLMIRRKKTTIFIEAQELTTVLELKRIVQGILKRPPEEQLLFKDDQLLDESKTLRDCGFTSRVAKAQDPATVGLVFREDASEGLQIHPYSTPLLPSVMKTGTDSLE", "length": 109 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZNU6-1", "protein_name": "Olfactory receptor", "gene_name": "Or5p66b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSWLENGNHTTVAEFLLLGLTDDPVLRVILFTIILCIYLVTVSGNLSTILLIRVSSQLHHPMYFFLSHLASVDIGYSSSVTPNMLVNFLVERNIISYLGCGIQLSLVAFFGAAECFLLAAMAYDRFMAICNPLLYSTKMSTQVCILLVVASYIGGFLNASFAMVSFCSFLFCGPNIINHFFCDFAPLIELSCSDVSVYVIATSFSAGSVTMITALVIAISYSYILITILKMHSTEGRQKAFSTCTSHLTAVTLFYGTVTFIYVMPKSSFSIDQNKIVSVFYLLVIPMLNPLIYSLRNNEIKSALKKQIWRKTVS", "length": 314 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZPU6-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC134485591", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKGKRRSTRYMFSRPFRKHGVVPLATYMRIYKKGDIVDIKGMGTVQKGMPHKCYHGKTGRVYNVTQHAEGIIVNKQVKGKILTKRINVRIEHIKHSKSRDSFLKRVKENDQKEKEAKEKGTWVPLKRQPAPPREAHFVRTNGKEPERLEPSPYGFMA", "length": 160 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ96-1", "protein_name": "Large ribosomal subunit protein eL21", "gene_name": "LOC102550668", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTNTKVKRRGTRYVFSRPFRKHGVVPLVTYMRLYKKGDIVDIKGMGAAQKGMTHKCYHGKTVRVYNVTQHAVGIIVNKQVKGKILAKRINVWIEHIKHSKSRDSFLKQVKENDQKKEEAKEKGTWVQLSLQPAPPREAHFVRTNGKEPELLEPVP", "length": 155 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQD9-1", "protein_name": "Developmental pluripotency-associated protein 3-like", "gene_name": "LOC120096627", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKSSEKVDPVVNPETQMNDGSQREDEEDSPDDSEILQPETLVKVMKKLTLNPSAKPPKYHRHQRVRLRIKSQPVGNRSERIMREVQSAFPKTRVRTLLSVLKDPIARMRRFVRIEQRQRQLEGNERRDEPFRCLCTFCHYQRWDPSENAKIGQNQKN", "length": 158 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQT0-1", "protein_name": "Glyceraldehyde-3-phosphate dehydrogenase", "gene_name": "AABR07071101.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILCIKPSSTTKYCLNQCYLISCINKPNLLDGVNGIPLDIVAINDPFIDLNYVVYMFQYDSTHGKFNGTVKAENGKLVINGKPTTIFQERDLANIKWGDADAKYVMESTGIFTTMEKAGAHLKGGTKMVIISAPLADAPILKYDNSLKIVSNASYTTNCLAPLTKVIHDNFGIVEGLMTTVHTITATQKIVDGPSGKLWRGGHGAAQNINPETTGVAKAVGKVIPELNGKLTGIAFHVLTPNVSVVDLTCHLKKPAKYDDIKKVVKQASKGPLKGILGYTEDQVVSCDFNSNSHSSTFDARTGIALNDNFVKLISWCDNEYGYSNRVVDLMAYMASKE", "length": 338 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZTK7-1", "protein_name": "Uncharacterized protein", "gene_name": "AABR07012426.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGDLEAKISGYTHISVQRFCYKWTISNFSFCMDGIRENITSPVFSLEGNEEVQWCLRIFPNGVDEESKDYLSVSLGLHSCPKSPVLAKVQFWIINAQGEKHQIKEIPNILSFSPKHQWGLRKFILREFLLSRRHGLLPEDQLILCCKVSVVGPSFSTPGHNMTPANKDPRQMLADDVGELWENSLFTDCSLVVAGQEFRAHKAILAARSPVFRAMFEHEMLESLTNRIEIHDIHLQVFKEMMAFIYTGKAPHLHSHSMATELLAAADMYDLQDLKVMCEDSLCRNLSVKTAVPTLMADLHSTELLKTRVMDFIILHASEVSETLEWKSMVESHPHLVEEAFGSLASMHYFFLEPSLKR", "length": 359 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZV50-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVARSWVCHKTYVTPRRPFEKSRLDQELKLIGEYGLRNKHEVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIVVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLRLAKSIHHAHVLIRQRHIRVRKQVVNIPSFIVCLDSHKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEKKEK", "length": 195 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZWL0-1", "protein_name": "Ribosomal protein L32 like 1", "gene_name": "Rpl32l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALQPLVKLKIVKKRTKKFIRHQSDRYVKIKRNWRKPRGIDNRVRRRFKGQILKPNIGYGSNKKTKHMLPSGFRKFLVHNVKELEVLLMCNKSYCAEIAHNVSSKNRKAIVERAAQLAIRVTNLNARLRSAENE", "length": 135 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A176-1", "protein_name": "Golgi associated RAB2 interactor 5A", "gene_name": "Garin5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRLRTSARSPAPAVRMAISPSGPLGFTSPVTQPRREASPGVPTTQGRGVAMKGGRDLKPASGRADRPLAQAYAPCRPGRLQRHLLSGEFDQLRDFPIFESNFVQVTRFGEVANKVTMGVAASSPALELPDLLLLAGPDKENGHLQLLGLFPLQFVQLFVHDVSRQQLKVKFRTGRAFYLQLRAPPETRDCEFGRWVRLLYRLRFHSPTCAVPFTHEDTVPEESEDEDEVEEGQLQPPEVRAGPRAQGCWARKDGKGPVSCHRGQTRPAGLRTLGALIQPRSFQITKGPEIKPAQLRAREMDF", "length": 303 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A9N2-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a77d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQNNSVSEFILLGLTEDPAGQKTLFVVFLLIYIGTMVGNLLIVWTVIASPSLDSPMYFFLAYLSLIDALYSSTILPKLLIDLLCDKKTISLTACLVQLFVEHLFGGVEIFLLVFMAYDRYVAICKPLYYLTIMNQRVCVCLVVVSWIGAFAHALVQVFSVYKLPFCGPNIIDHFACDMYPLLGLACTDTYFLGLTVVGNNGAISVVVFMLLLLSYGIILNSLKTHSQEGRRKALSTCSSHIMVIVLFFVPCIFMYVRPVSNFPLDKFITVFYTVFTPMLNPLIYTLRNLEIKKSMEKLCRKIFTSDRIRISSCYS", "length": 316 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAM5-1", "protein_name": "Preferentially expressed antigen in melanoma-like", "gene_name": "Pramel", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVKTPNKLLELAIHSLLNEESAAIQALEEIPRELFVPLFIAAFEGGHKNVLSAMVKVWPYYCLHIGSLSIQEPQHELLKAMIENLPVYPAPSSSSRGPKLRILDLRQDTDCRITCPEVSTKTPSCFYSCAYSDRSITKIERQLCCVNAECKTLLPRPVELLVDLSLDGSLMEKEFLVLLMYKIEESLGSLHVCCRDLQIDKLCKCKCTLKFLDLKCIDQLSVDRGSLSDITSILCRMIHLESLSLSNVTFRSLSGKVFKIFLSHLQRMEHLKELSLSSFCLKNHLDRVLRILPPGLDFLYLPFCDLSYRDFKFMSQSPQVTHLKLLNLSNNPMYWGDFEPFHTVLINLSGTLQHLEINHCLISDSAMSALIPALIRCTRLRVLGFASNPISMPMLVNIMHNLTPMKELKYVIYPIPVHCYERWHFQGSLDRQKLAIVQLQLKAMLELAHREDMNWITYCE", "length": 461 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AAN9-1", "protein_name": "Similar to human chromosome 6 open reading frame 52", "gene_name": "C17h6orf52", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVETQSPGKECAVLPLWVLTVTSCPLPSAIREQLRVHHSLRCHRDNHYELLHSFYWLSCYSRGSTLSGNGLGPLCVTENPELLAGPWAIPEETTDPAENQEEDFLRDPNLHLNIEESDKEFMAVREELYDSLMNRRWHCLDTVLSNVPDELPQCEVF", "length": 157 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ABB6-1", "protein_name": "Olfactory receptor", "gene_name": "Or13a27c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "VNCIWHSKMVSPNQTVVTEFVLQGFSEHPSLRLFLTGCFMSLYTIALMGNIVIIALVTSSTGLHSPMYFFLCNLATMDIICTSSVLPKALVGLLSEENTISFKGCMTQLFFLVWSGSSELLLLTVMAYDRYVAICAPLHYSSRMSPQLCGALAMGVWSICAANASMHTGLMARLSFCGPKVITHFFCEIPPLLLLSCSPTYVNSIMTLIADAIYGGINFVLTLLSYGCIIASILRMRSAEGKRKAFSTCSSHLIVVAMYYSSVFFAYISPGSSYNPERSKFTSVLYSVLSPTLNPLIYTLRNKDVKLALGRILASFSH", "length": 318 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADX2-1", "protein_name": "Olfactory receptor family 4 subfamily A member 80", "gene_name": "Or4a80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGQSKIVTEFVLLGFTQDPAGQKALFVMFSLMYIATMVGNLLIVGTVIVSPSLGSPMYFFLASLSLMDAVYSTAISPKLIVDLLREKKTISFRACISQLFIEHLFGGVDIVILVAMAYDCYVAICKPLHYLIIMNRRVCILFLVMAWAGGFAHALFQVLAVYNLPFCGPNIIDHFGCDIYPLLLLACTDTYLIGLTIIANGGAMCIVIFILLLLSYAIILRSLQNHSQEGRHKALSTCSSHITVFFLFFVPCILMYVRPVSSFPIDKSITVIYTVVTPVLNPLIYTLRNSEMKNSMEKLLQKILSPNRLRLLCCLYY", "length": 317 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AEJ6-1", "protein_name": "Peroxisomal biogenesis factor 11 gamma", "gene_name": "Pex11g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLNGLASALESYRGRDRLVRGSVGPWRDRSDLEFGQDSEMRKTGQRGGPKGTDIGRLVSYMRTSYLSLPNCWPYKCVLALQIRTLGYGCQLIGGVLVEQCPSRSEVGRRLLVVSAQLSHCRTVLRLFDDLAMFVYTKQYGLGAEEEDVFIRWLSVLSNMADQLYYPCEHVAWAADAKVLQVDSARWWTLSTAFWSLSLLLGAVKSLWTMLKLRQKLRSPTGHFASQLPRSKWRAVEARIWSEALTLLSNLADLANAVHWLPPGVLWAGCFPPWLVGLMGTISSILSVYQAARAGKQAEVDSP", "length": 304 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D6R901-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 21", "gene_name": "USP17L21", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSNRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKMLTLLTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "E0CXP6-1", "protein_name": "UMAP1-MVP12 associated (UMA) domain containing 1", "gene_name": "Umad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFHFFRKPAESKKPSGPEPEADGFVLLGATANEVRCKTSEAEGSQALETGKEDTSSVTVSGPETENQTGQTLQNNSLTAELLSDVPFTLAPHVLAAQGTISDLPDHVLSYDVGDNLSRFWYDFTLENSVLCDL", "length": 133 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E0CZF1-1", "protein_name": "PRAME like 34", "gene_name": "Pramel34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQTPPTHTLLTHEALIMSSLEELPTVVFPALFKEAFAGRHTNLLKAMVAAWPFPCLPVGPLMKKPNLETLQALLDGIDMRLTREFHPRRAKLQVLDMRNMYHAFWNIRADANDSDCKSKTLDEKQLVKVLPRYARRQRLKVIVNLSISSHFNKSKAYFLNWAKQRIGSLYFCCIKMRIWDPPDQVIRDIFNVFDPEHITELELNTDWTLLQLAHFASYFGHMKNLQKVFLAPLHKNTSPIINITNATEAKCVHKIISQFSQFNCLQHIFMKHVHFLRDYMNQVLGCLMTPLETLSITQCLISQRDFDLFSCSQNLFKLKHLEIRGMILYALDLMPLRVLLEKVADTLEILDFQWCRMKDSQINALLPALSQCTQLNQINFYNNDFSMCTLKALFQHTANWSKMNVEQYPAPLQCYSELGHVSVERFVQLCQELMYTLRAIRQPKSISFATDNCQKCGKPCVYDQGPILCSCFQ", "length": 475 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1B8K9-1", "protein_name": "40S ribosomal protein S6", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKLNISFPATGCQKVIEVDDERKLRTFYEKRMATEVAADTLGEEWKGHVVRISGGNDKQGFPMKQGVLTHGRVRLLLSKGHSCYRPRRTGERKCKSVRGCIVDANLSVLNLVIVKKGEKDIPGLTDTTVPHRLGPKRASRIRKLFNLSKEDDVRQYVVRNSLNKDGKKPRTKAPKIQRLMTPRVLQHKRRRIALKKQRTKKNKEEAAEYAKLLAKRMKEAKEKRQEQIAKRRRLSSLRASTSKSESSQK", "length": 249 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BBD9-1", "protein_name": "RNA polymerase II subunit A C-terminal domain phosphatase SSU72", "gene_name": "LOC112445820", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPFLPLRLAVVCSSNQNRSMEAHNILSKRGFSILSFGTGTNMKLPGPARDRPNVYDFRAMYDDVYKDLLRKDKERYMQNGVLRMLERNMEKEMPRPERFQECKDLFDLILTCEERVYDQVVEDMNSGEQETCQPVHVINVNILDTNKEATLGAFLICDLCQCVQLMGDMEDRIGELLQAFEEKSGRSFLHTVCFY", "length": 195 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E1BLY1-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIIRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLSSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F638-1", "protein_name": "Moesin b", "gene_name": "msnb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSINVRVTTMDAELEFAIQSSTTGKQLFDQVVKTIGLREIWYFGLQYQDSKGFSTWLKLNKRVTAQDVRKENPLLIKFRAKFYPEDVAEELIQEATQRLFFLQVKEAILNDDIYCPPETAVLLASYAVQMKHSDYNSEHHIPGYLCRDKLLPQRVLEQHKLTKEQWEQRIQVWHEQHKSMSREDAMIEYLKISQDLEMYGVNYFSIKNKKGSELWLGVDALGLNIYERSDKLTPKIGFPWSEIRNISFNDKKFVIKPIDKKSPDFVFYAPRLRINKRILALCMGNHDLYMRRRKPDTIEVQQMKAQAREEKNKRQQERALLENEKKRRENAEKETEKIARETMELMERLRQIEEQTKKAQEELEEQTKRALELERERKFAQEEAEKLEKDRRIAEDVKTALLQQSENQTKNKDNLATELAELTSKINLLEDAKKKKEDEARKWQRRAIMVEVDLEKTKEELKSKLIGVHIQATSQTENDHDENDESSAEASAELTSTGSFRDRSEEQRITETEKNEPLQKRLQALSSELADARDDSKKTANDLIHAENVRLGRDKYKTLRQIRQGNTKQRIDEFESM", "length": 577 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FA22-1", "protein_name": "Protein tyrosine phosphatase type IVA 3", "gene_name": "ptp4a3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAWLNGLYPVEVCYNSMRFVITHNPTNQTLDTFIEDLKRYDAKTVVRVCESTYDKTPLEKHGITVMDWPFDDGAPPPTKIVDDWISLLKKSFSEDPGCCVAVHCVAGLGRAPVLVAVALIEGGMKYEEAIHLIRLKRHGAFNSKQLTYLEKYRSKKRLRFKDPFKHRSKCWLM", "length": 173 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FE27-1", "protein_name": "Beta-1,4-N-acetylgalactosaminyltransferase", "gene_name": "b4galnt4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRMRFPLKKIRKQFKLLLLLVLLMFAIGFTYLHINQGKAIKLHFNYGKDMERQAEGIGSSPKKHLSSSINPFEHGDAADSQEDGWGGEELNESAQESRANAEMHTLLAQKFLGLPWKPEYKGQANLHVFEDWCGSSVSQLRKNLHFPLYPHTRTTVKKIAVAPKWKNYGLRVFGFIHPYKDGDFQFAIASDDNSELWLSSDESPLNARLLVYVGQHGSEWTAPGEFSKFRSQTSKPVRLMSSRRYYFEVLHKQDDRGSDHVEVGWRPFLPGQKFDVIDSAYISLYTDESSLKMNSVHHIPQTLASHSLALQIYHRTETHTADMLKPDPRDTFYKIPMIDQSRLENVLPSCVYSPTYVVKDFPIARYQGLQFVYLSYVYPNDFTRLTHMEKTNKCFYRESPVYLEKFGFYKYMKMDEEEDDQPVFFPKPDDFLEEEEGVDPEEAINSSNRPVKRSGPSYQTSRITAATASSKPDRLDGGSKSSVFQQEKQYVQFKEQERSKKRTKGERFYRHSQVVDDEMTEIRQVKGSTGVLESQSGSLNEQTGPSEENGDSQTLSLVQRGRSLAWVLPDPALQSESKLIETASPTVKERSPFKLPHLYVLANRILGNAGKPVVEKESNSNKIYITRPRPPVSRPKPPVEVFPGVFLYQSRKSKRLVDLSSKWRSLKTQAAASAPWANFPLMDHKTSTQSALLKQSHLSSPTEPGPHNKGDPTASISDPDSVPPSSSEKRDHPGLNSSSQPPEEEPTKISEMAEGLDVAPQSRGLEEGEMSEYSYEEAEVRPHLAEEAINWQRTFSVNPVDFELLRSDWNDLRCNVSGNLQLAENEVIDVISQFMERLNERNRGIYTLARIVNVEKRRDSARGNRYLVELLLMEGGKRLVRLSEYIYLLLHRSRFEEGIESREGTVPSSHRTPSKIPLPSGSSAQTHTTTPWSTSWAKPLLCQPIMLQWRHDVMVHFVVPVKNQARWVQQFISDMELLHRETKDENFSVIIVDFQSDDMDVEQALKESTVPRYEYLKREGNFERSSGLQMGVDTIEDSHSIVFLCDLHIHFPHNILESIRKHCVEGRLAFAPIVMRLDCGSSPLEPDGFWEVNGFGLFGIYKSDFDKIGGMNTEEFKDHWGGEDWELLDRVLQNGLEVERLRLRNFYHYFHSKRGMWNVPVKRASQG", "length": 1167 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E7FFR8-1", "protein_name": "Ubiquinol-cytochrome c reductase complex assembly factor 5", "gene_name": "uqcc5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRKSQNLKYMLSLVPGKKRFGVYRFLPVFFCIGGVMEWIMINVRIGRETFYDVYRRKQSERAYQQKTEEGLIMLTDSQAK", "length": 81 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9PUW9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r143", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PUZ0-1", "protein_name": "Apolipoprotein L 11b", "gene_name": "Apol11b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWNEISEDIRKVECRTFEKVIDNATEDLITDLRSLITEDGAWNGFVEAVELSSEEGEALRDALKERLAQDPTDENDRPQREQQKERFLREFPQLKKKLEDHIRKLRDLADKFDQVHKDCTISNVVSTSASAASGVLALLGLVLSTVTAGASLALSASSVALGATSSVSSFTTTVVEDSMTLSYESEARNLIGASMNVLEEILSIMPKITCKFYNTVADLVKAFKTLKGQIQTIRRARSISRRGAQARNLTSTGRSSGQGVSQMTRGARIRAGVFTSVFLGWDVYDLVTKQRICMMGEKQSQVEHCGTWLASWRRTFRNLSRSTMLCSQTCLSDALP", "length": 337 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PV04-1", "protein_name": "Eukaryotic initiation factor 4A-III", "gene_name": "Eif4a3l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTTRMATSGSARKRLLKEDGMTKVEFETSEEVDATPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIMKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACVGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLTTRAIKMLVLDEADEMLNRGFKEQIYDVYRYLPPATQVVLVSATLPHEILEMTNKFMTHPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCITKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNLADLI", "length": 411 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVP9-1", "protein_name": "Predicted gene 4884", "gene_name": "Gm4884", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSENLQSSPFFGTESTLHPSLPLLSNSKQPAGTVCNFSRVSTPDVSSAWLLPSASSTSLQPLMVVQMETSLGLPPSGQTYCQLQSPELCNTCVQVSQIRPPAVNGDKALTAPIHSPSQFLALPPAPSLEQPENKTMPEIKEGTKENQDTPVLTLEHPDLQQPLHCTDTESLRQKPDSDNAHLGCICMGPKELVGLENEIGSSFDFKDITRFGADIQLPQLLNTLTDIDQDQSCENWRVTSGLFDQVRENKHKSFELLEGAPQAKFQHWDLVEGEGAVGVAGASDRAIDNMAKHPEGKAPKGPPSKNRRARKQEQERPSGPENKSKKTQELKQSRNRVKAEKEPSIPKTKRKRNPPELSQNSFKKPRTNLAMHMLESVQVFHPLGKKSEKKTGISSFRGLRTFTSNKDSGPGSVTTTVLNMPCESQGPPKSPGKVQSAESSVGKDCLSPSQYELPPAGKVKLVPLPFPTLDKPQSRPASRKPLSLALRRPTAVYPVQHHSHSVQPTTLRPAQPPPASSSLIASAKPAPPISSSATGPNVTNPNQSSAVPQLATSRPVPYRASSHTSFQRELVSAARNKVPSPPRPVPYRASSNTSFQRELVSAARNKVPSPPKPQTQYLLHDFSRQPIPWKKVDILGPVVSQPITKEQRPEREAMKRRSQQERENAVKNPSTGKLQIFLQRERDMEISQYYGYAM", "length": 694 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVW0-1", "protein_name": "Major urinary protein 8", "gene_name": "Mup8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCVGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIRVLENSLVLKVHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNAMDLVPEHVLVLTRQIAASRPENEEWPEPPVLSGDFSPGLHHHPFLSIQHPQYKFCDLHSILSH", "length": 235 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PVZ7-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYFCLPRFSIISMLTGNGSFVTEFVLAGLTDRPELQLPLFYLFLIIYTVTVVGNLGLIILIGLNPHLYTPMYYFLFNLSFIDLCYSSVSSPKMLMNFVFEKNSISYEGCMTQLFFFLFFVISECYMLTSMAYDRYVAICNPLLYKVTMSPQVCSMLSFASYGMAFAGASAHTGCMLRLIFCNANVINFYLCDILPLLQLSCTSTYVNEVVVLIVVGINITVPSFTILISYVFILANILNIKSTQGRSKAFSTCSSHIMAISLFFGSGAFMYLNHSGSMNQGKISSVFYTNVVPMFNPLIYSLRNKDVKIALKKVMMRVHSRFIS", "length": 325 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW18-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r257", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPLSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW59-1", "protein_name": "Olfactory receptor", "gene_name": "Or8b50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALANGSFVTEFILLGLTDQPDLQMPLFLIFLIIYLITAFGNLTLIILIVLNSHLHTPMYFFLFNLSFIDLCYSSLITPKMLMNFVLEKNIISYMGCMTQFYFFGFFAISECYVLTAMAYDRYVAICNPLLYSVAMSPKMCSYFILGSYFMGFSGAMIHTGCVMRLTFCDGNTINHYFCDLLPLLQLSCTSTYVNEIELFIVTGKDIIVPTVIIFASYGFILSNILKIRSTSGRSKAFSTCSSHIIAVSMFFGSSAFMYLKPSSAVSMNEAKFSSIFYSIVVPMMNPLIYSLRNKDVKVGLKKTLSRMFSHNLISL", "length": 316 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXC3-1", "protein_name": "Cytochrome P450, family 2, subfamily c, polypeptide 69", "gene_name": "Cyp2c69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFMLLLSLWRQRSARRNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEVFSGRGSFPFFDKVSKGKGIGFSHGNVWKATRVFTVNTLRNLAMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGRHNKFFKNHTWIKSYLLEKIKEHEESLDVTNPRDFIDYFLIQRRQDKGIEHMEYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRKHMPYTNAMVHEVQRYVDLGPTSLVHEVTCDTKFRNYFIPKGTQVMTSLSSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDTTPKYSGFSKIPPKFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PXM9-1", "protein_name": "F-box and WD-40 domain protein 24", "gene_name": "Fbxw24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLSSFPMMEIFSYLDAYSLLQVAQVNKNWNALASNDFLWRKLCQERWLFCDMVTLQLLGKETWKQFFVYRTWQEHVKSRAIPEDFTYKEIPLECGVRGYAGYISGCALTRNGQGKSVVCMVSSKNKISTWDISESVITWVSPVQPASIKLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLAGDILGNLYIFRIPDLHLISTVNVFPCGFDKIDCSPQKKWVLLSQNHPCIYPKVFYMSSLLRTSEFSDPVSTVLEFSLCKRAFWTPRREDRITLMSRRGRPIVTRFETFDMKLEENGNKTIVKGDLVASFSLQDYNENPKWMGVSDKSVIVCSTGSSLLLFSMKGLHLQTFQYSPEMIVRLWVDPVHVIITCNDGSIDVYMWEERSLLLKMCYRLQNGRHLPPFGFIKNLLCDDVSIVQLMIDRQGPCFLMAYTLNICS", "length": 466 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q069-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r157", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCHFEVGTVANVFLFVHNFSPVLTGYKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0V3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGVAIIKENQTQSKMDFWNMGIKILFLSQTTTGILGNFSLIIYYVVNYIVHTLKPTDLILMHLMTSNALMVLSTGVLHTMAAFGLAHLLNDLGCRLILYIQRVGRSTSIGTICLLSIFQAITISHRVSCYKGQKIKSSKYIGYSISLLWVLHMFLNFILFVDIFIKRNRNNMTSDRDFKYYSIVERNEFSDSLYVALVVCPEIFSSVLITCSSGSMIGILYRHKQRVQHIRSFHVSSRNSPEWRATQNILVLVSTFLAFYTLSSVLQGCIALLNNPNWWLVNITRLTSLCFPTFAPCVLMSHYSFMPRFSLVWTWNKTS", "length": 319 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C7-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A2", "gene_name": "Speer4a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWMGETREGRKDADLPSKSNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHNLEMENMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIHQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 252 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1N7-1", "protein_name": "Predicted gene 8126", "gene_name": "Gm8126", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNRNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKITQSINDTIEKYKEFIEDKDSYSFMHTYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEENRFCHESSKNIHPKY", "length": 198 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q328-1", "protein_name": "RIKEN cDNA 5430401F13 gene", "gene_name": "5430401F13Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSRILLVLLSIALLALTSAQRVNEDDGSALQEEDALEIGDSNQQHDDIHERLNEIKNHFQDQISQHGKEAIKSKKGKNGPRSRRSSDDDNLEVQDHQSGNEQAGGGQGGRGRSELKGQNGKGSQKGKKGKGGQQEQKGKGGQQKQKGKGGQKTKRGKGGQRSQQDNVQEVYQE", "length": 175 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q346-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r160", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSKLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q366-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4f2", "gene_name": "Speer4f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTMCVRLRRLFQRANVDGRETREGSMDAGLPCERNEGRRRWTWRMWMAHRQTSSPVPVTSNQFEKEEEELMEEIQLISQEKNGLRDYLNLTLGSKITRLNQSYEELKLKQKELMTLQHDLEMATMEAREENEELKKEINFYSNLHSRALMENNLIKKKLMTLQQESKEVQAEWASIQQHLDVNLSGKDEQENNSILDTQEHQVSETARELGLATDQEDSILQDELPPQEAPAEELSPQEAPAEELPPQEAPAEQLPPQEGPAEELPPQESPAEHHLQHPQSFSDESSYITYPEWE", "length": 295 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3G0-1", "protein_name": "Zinc finger and SCAN domain containing 4B", "gene_name": "Zscan4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPIPDNAQMPVDTTQDRLLATGQENSENECNTSCNATEVNVGESCSGNEKDSLLITQKEQNHEHEEGNVVCQFPRGARRASQDTSSHHVDFPSALTPADVPMEEQPMDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKTDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQPISDPVLGKNHEANLPCESHQKRFHRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCITCQKIFKRVSDLRTHEIIHMSEKPFKCSTCEKSFSHKTNLKYHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 505 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4E0-1", "protein_name": "RIKEN cDNA 5031410I06 gene", "gene_name": "5031410I06Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTFLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPSSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q501-1", "protein_name": "Predicted gene 2237", "gene_name": "Gm2237", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENVDEGETRPTEKEEGILSHEKGRRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSPAESRTWH", "length": 211 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5G7-1", "protein_name": "Oogenesin-1", "gene_name": "Oog1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGYIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSAGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFSLGDSEKLDEETIFSLISQLPTLHCLQKLYVNDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPYCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELDSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPLECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVELL", "length": 496 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6D7-1", "protein_name": "RIKEN cDNA 1700024B05 gene", "gene_name": "1700024B05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESHDNPVSAGRTSSQNCNITNHMKNMNKLDDMKFYIRKINAELEELFRILDIDMNTDLNYRMNTEFTIIKSQHEKTMLDMEKMKQSISDSIDKYKEFIEDNDSYSIRHTHLLKECNQLKEKVRMLLNENRKLLVEQADQEASFGEEKSSVMRPARTYIPSAKQQQL", "length": 167 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q7M8-1", "protein_name": "Predicted gene 5796", "gene_name": "Gm5796", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQSGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8A4-1", "protein_name": "F-box and WD-40 domain protein 28", "gene_name": "Fbxw28", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSVPMMEILSYLDAYSLLQAAQVNKNWNELASSDVLWRKLCQKRWLYCYMFTLPLHGLETWKQFFFDKTWQEHAKTRAKPEDFTYKEFPVEFEFRAHPWYISRHGLTRNGQEKSAVCMTSMNRISTWDIHEGAMTWESPKQPSYIVWMTTLPEMQIAVTIDMQSTIKLWDCHNKEVLASKTGLFFGCKLLQSEFTKDGPIVLVGDACGNLYIFRIPDLHLISKVNVFPYSIDELYFSPQKKWVFLIGHRLNDLTKVFYMSSLLRPSEFSAPVSTVLKVPVIRKVFWTPRREDRITLMSLILPKNITKFDTFDMKLEGIGNKVTIQGYLTASFSLAEDEGRPDYFGVSDKDVIVCSTRFSLLLFDINGLRLQTFHYCPEEIWRLWVDPVHVIVTCDAGSLDIYAWEKRSLLLRKCYRLRNRNYQQMSGYIIKTLCDDMSIISVANNSPKPCCLMAYTLSVCS", "length": 466 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8I6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDLVPKNPPTDLKCKLAHFFHMVARGTNMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVRYSCYSCWLFSVLNNAYIPMNVRGPKKSHNDSDSQGKRMCSISVVNVDMNYLQFSYDIIFIGIMVWTSVSMVIHLNRHHQRMHYIHNPNQSNRGHAETRAAHTILMLVVTFVSLYILNCICVLFHVSFVESRRWLRNVIEFLALSFPTISPLLLIFRDPRGPCSLYFNVGLEIHVTGKVITEEQ", "length": 310 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8L6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r132", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFFSVLSNIHIPIKVTGPQIIDNNTYDKSNLFCSTSGFIVGIVFLQISHDATFMSIMVWTSVSMVLLLLTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPNDPCSVLFKC", "length": 297 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8T0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQTGLGVLANTVLLFFYVFIILGHRPKPTDLISCQLSFVHIMVVLIGGDILLADIFESLNIGNDFKCKTTFYLFRVMRGLSICITCLLSVFQAVTISPNTSVLAKFKQKVKKYMTHVFLCIWFFNLSFSTNQIFYVGGFTNVSETNQMQVTKSCSLLPMNYIIRGLIFTISISRDVFLVGVMLTTSVYMVIFLFRHQRQCKHLHSFSHPRESPEKRATQTIMLLVSFFVVLYWMDFIISFTSEMLRMYDPVILTLQKFMMYAYPTITPLVQISSDNRIIIMLKNIQSKCHPSFSLKDFFFFI", "length": 311 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q8V7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r173", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALNKALKTTEEVALQIILLCQVGIAAVANILLLVHNLSPNFAGPQLRPKHVILAHITVGNLLIILLTGFPSNIIVFVPRNPLNDLNCKLEYFIRLVARSANMCTTCVLSTYQFIVLVPGKWSRMILRGNTSTFVHYSCNSCWIISVLNNVYIPIKISGPWNTDNDTDLNSKWVCSMSGFELVMVFLRFVHDTMFISIMVWTSVSMMLLLYRHHQSLKHIHRSNGSLGLQPEARAAYTILMLVVTFVCFYLLDCMCIFFHISFVHFRVWLRHVNEILAASFPTLSPLMLIFRGPKKISAKGINTENAFINSH", "length": 313 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q9N3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r152", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFASKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFGSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHRQQMQHILTPNQDARGQAETRATHTILMLVVTFVRFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QAN3-1", "protein_name": "Predicted gene 1979", "gene_name": "Gm1979", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRETREGRKDADLPPESNEGRRRWTWRMWMAHRQKTSPVPVTSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHELEMKNMEARENKQELKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9QD93-1", "protein_name": "Granzyme K", "gene_name": "gzma", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICRNLIVFHFLVFTFFKVTVCSDVSIVGGKDVKKALSWMVSIQVNQNHKCGGILIHKEWVLTAAHCKEDSYSSVTVLIGSLSLSKGSQRIAIHNYEIPETFNKKTKKDDIMLIRLSKKVKAKPYKIPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQCNRYYNRNPVITKDMLCAGNTQQHRGTCLGDSGGPLECEKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILKQQFNSTRF", "length": 257 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9QLQ1-1", "protein_name": "Defensin, alpha, 35", "gene_name": "Defa35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHDELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LPT0-1", "protein_name": "Gap junction protein", "gene_name": "Gjc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCCSFLRQLLARESQHSTPVGRFLLPVLVGFRLLILVSSGPGVFGNDENEFMCHLGQPGCKTICYDVFRPLSPLRFWAFQVILMAVPSAIYVAFTLYHVIGYWEVPGRNKEQEAQICKGGRCKDVSGAMSLKLLWAYVAHLGVRLVLEGAALGVQYHLYGFKMPSTFICREDPCIGSTTCFQSHPSEKTILLNTMFGISGACLLFIFLELVLLGLGRVWKTYRHKLPLFKNLSTSERSVRHKDTTDDLSVVETKEPF", "length": 257 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ4-1", "protein_name": "Alpha-1-B glycoprotein like 1", "gene_name": "A1bgl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLLVLLEPLASLTLTCKVCEPSKDLHRILHLSSMETACTLSLALPPTLPSASLIFSASGVHTLILLRVRLNHSLILLSLIHTGPLPRPWLSANPVPWITPGLRTFLLCQGTVRDVVFMLRREGDDGNKEKEQGIFQVHEPGNYSCNYYTNTEYTPSKPSGTVTIKEYVIPPPPMLTSLESSTVDEPEMTQMSLLCVAPLSDVEFQLRQGEREMKVLIVSTSPERASFYLKLSDMGDHSPFTCRYRLNRMTAWSEDSKPVQLMWSDETLPEPVLTVEPSPHQSFEPGSTVQFRCTAPKAGLRSEAGLRFGLHLEDLYDHRLLQTQKSSGNETVFQLRNVSATDSASYSCIYTELTPPYSGSAPSDFVILRVNGPPPPPKLQALWTGKVFAGHDVVLRCQSDVTGVIVELLRDGKFVPYRILRVLNNYSDLGLHSVGPQHTGNYTCRYTSWLPEPVQSEPSNPVELLVEGMASGVVVVGFCLLIFPGLCILVNCAI", "length": 495 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M6N1-1", "protein_name": "Zinc finger protein 945 like 1", "gene_name": "Zfp945l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTASLVNVSKCLLTFRDVAVEFSMEEWECLNYSQKTLYRDVMMENYNNLLFVENHCKYKKVLDQDPNSIVHNVNIYEKAYECNELVKMTHESSQGTPFKTKHKDASLQISTLNRQKIGNTRDEPCKFKDCINFLNVFVIRQNQRIYIGEKEPTTIEYENHYNSKHEVMLKQSNSTGNKPHIFRKYGQCFKIYSSFSRYQNDHTSEKFYKCIKCRKSFLHLSQLKVHYKIHYRKYPCKCTACSKCFYHTFGFKRHYSIHPEVNTYKSSDCDKSFIYYSSLRKHQKIFGGERHYECNEGLRSLYTVFQPVYYYIPHIGEKAYKCSECEKCFTRKYHLTVHQRIHTGEKPYKCGECDKCFTRKYHLTDHQRIHTGEKPYKCSECKKCFTRKYHLTDHQRIHTVEKPYKCSECGMSFMKKYHLRSHQSIHTGEKPYNCSECDKGFTYKGHLRRHQKIHTGEKPYKCSECAKCFTENSKLRRHQRIHTGENLYKCSECDRCFIENNKLRSHQKVHIGEKPYKYSEYDKCLTQKGSLRSHQLIHTGEKPY", "length": 544 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M7A9-1", "protein_name": "Large ribosomal subunit protein uL6", "gene_name": "AABR07026048.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANRLAHRPIQWRNFLSQDSLDQDTMRKKTILSNQTVDIPENVDITLKGRTAIVEGPRGTLRRDFNHINVELSLLGKKEKRLRVDKWWGNGKELATVRTICSHVQNVIKGVTLGFCYKMRSVYAHFPINVVIQENGSLVEIRNFLGEKYIRRVWMRTNVACSVSQAQKDELILEGNDIELVSNSAALIQQGTTVKNKDISKFLDGIYVSEKGTVQQADE", "length": 219 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M9J5-1", "protein_name": "Uncharacterized protein", "gene_name": "Esp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "ITFLPVTLFLIILLWPSMITEGRVLTQNQKELSISADHNKNHKSDLDKIEFQGQPNIQKAVEMTICASDKDQTLLEDQANANQDKQLYKDSHLLCGRSLDHIVK", "length": 104 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QDL3-1", "protein_name": "Novel nacht domain containing protein", "gene_name": "LOC560232", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDKHTPGDLDLSTGCSSVHQNRAEAEPSCVSMKSDVSMDPPTNFKSGNTGPAVSSRKRKRAEAEPSCVSMKSDASMDPPLKFKSKNTQPAVSVDRDDQSGDLLQDSLQPEHDELQRVKEQHKTTMKNKHERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVIQMEKRARTKPSQHTPVYCNDIFKASAGAGHEVKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDALVYSGICTEIFKEESVIQQRKVYSFIHLSFQEFLAAFFVFYCHLTKKRELLELILGYSYDQYLQSSSEKSLYDLLSSAVDEAVRSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESSESIRRITQYIKDQIKSDDYFKRAAERFINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDEFELQKFNTSAEGRLRLTTAVRNCRRAL", "length": 725 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QGM0-1", "protein_name": "Galectin", "gene_name": "lgals1l1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTVLIQNMAFKVGQTLTLTGVPKPESPEFTIDIGNSSEDIALHINPRFDAHGDQCIIVCNTFQNDCWCEEHRDENFPFVQGEEFQIKITFTNEEFLVTLPDGSEINFPNRQGSEKYKYMNFTGQARIQGIEIK", "length": 134 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1QMQ9-1", "protein_name": "Uncharacterized protein LOC541480", "gene_name": "si:ch1073-398c20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADIKQESDDIRIAEVFTLKQEDPEEQTDLLPLRKEFQGLDNVKEEEALVEEHQDITPAEKRITCSETENTTQKASEKTGSRSSFTCEQCGRDFAKQGTLNNHMRIHTGEKSFTCQQCGKGFTQKRTLRNHIRFHIEAESLSCQQCGESFTQKQDLTDHMRVHTGEKSFVCDQCGKVFLRKDGLEKHLKNHHKEKPHVCPCGKSFTDKTKLEEHTKTHTGEKPHTCDKCDECFSGKYDLIRHMRFHSAETPYICQQCGKSFALKRVLMTHVKIHTRDRPFLCKQCGKCFYRKDNFNRHVRVHTGEKPYACSECGKSFSERFQFNEHSRTHSGVKRFSCEQCGRGFNRKTELKRHMRVHTGEKPYMCPQCGKTYAFKTGFDIHMLHHNAEMPYICPQCGERFSVKQRFDVHMKIHAGNSDK", "length": 420 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R1Q6-1", "protein_name": "Uncharacterized protein LOC641576", "gene_name": "zgc:152710", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLIWTQFGVKHKNVKCKVRVIHGEEGSWSSEEVREEPEVSSPPPSPECVDYYSVLGVSNDSNEEEIRKAYKRLALRYHPDKNSDADAEDKFKQIAQAYDVLTDPEKRNIYDQQGLTKGGVAPTCNKTDPSHNSKADAHSWHMFFNFDLDSDDDLFNPFTRNPLPHLSRHHGNKGGLKPAGDAEVHDLSVSLEDILMGVTKRVKLTRLRQTDKHTLKPEERVFDVEVKKGWKEGTRITFPNEGHQMLGHAPNDLAFVIKEKKHAHFRRDGSHIVYTCTITLREALCGCTVNVPTLDGQMKPLPCSDVIKPSSVRRLIGEGLPRAKNPAQRGDLLVEFQVVFPDRIPPSSKEIIKHSLGQC", "length": 360 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RA39-5", "protein_name": "[F-actin]-monooxygenase mical2b", "gene_name": "mical2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGETEEERTSQAGQLFENFIQATTCKGTLQAFSVLCRQLELNPSDHRGFYSSLKTAVTFWKAKGLWGKLDKRAGHKEYSKGRACADTRCLIIGGGPCGFRTAIELALLGAKVVVIEKRDTFSRNNVLHLWPYTIHDLRNLGAKKFYGKFCAGSIDHISIRQLQLMLLKIALIVGVEVHVNVEFVKLLEPPEDQSTDGQGWRAEIRPADNPVSDYEFDVIIGADGRRSTLDGFRRKEFRGKLAIAITANFVNRNTTAEAKVEEISGVAFIFNQKFFLELKEETGIDLENIVYYKDNTHYFVMTAKKQSLLDKGVIINDYIETERLLAFDNVNQEALLSYAREAADFGTNYQLPSLDYAINHYGQPDVAMFDFTCMYASENAALVREKSHRQLLVALVGDSLLEPFWPMGTGCARGFLAAFDTAWMIKGWAQGKEPLDLLSERESIYRLLPQTTAENISKNFEQYTIDPATRYPNLNSSCVRPHQVRHLFISGEQDLSSLERSGQTRRSVSISRRESEVRPGRLLLWCQNQTQDYRGVNVTDLNTSWRSGLALCALIHRQRPELIDFDSLNEADCAKNNQLAFDVAEREFGIQPVTTGKEMDAERGPDKLIMVLYLSKFYEMFHKSTQSVTGLPKEIDANNGDCSSKTANSLYNSINHARKRIPKLDKKLEESDVNRKRKKASSHHEELMSCQTAPPAGEREEQKENKVRSMATQLLARFEENAPSCALRRQSDSESDSDADRPVSLDLTENPRFARPKIEPTHPSTTPDKAKWQPSPYLRLLESNTRSETLHTEHYVESQSSHRLTEIQSECQYSSVSSAYKSSERRPRSPLIPFTPTLSPMMHCLQQLEEQVIQQRKREPLNRKSIKERAQKLSSLFTGNPAQPQTDESSPAVSPSSPPQTIPESSTLSCLLSPAPSLTHKQCSEASETHLKADKHTEIRRVERLDPSKQRTVGKVSSAIGVKAATLAILYETDHRPNNPITLSLTEARRCAESGLVSVRKEFSASLGGSDTCVFCQKRVYIMERLSAEGFFFHRECFRCHICGCSLRLGAHTFDSQQGTFYCKMHFSQRKTSTRHRRGEIQDGGIRSSSITISNHTSTDGTRGQPSGGEFDSSTQQDLQTLPDSKEIISVSEVKDSSKKADPADSAPACPDSPLQKVKRSTAKGEITNKNILWKKKIRSTLPLVLMKKFHRGKPEDKTEVLAEEDGNSDFEEIHESLSSKKPSNPSTDSNCLPTKDNSSTPLDEIPKIPLYRTHVLPEYPKPSSSSPEPIVTSISSDPISFSPKKKLTLSLSEKEKLLNWDLTNPGKSGAEEQQQQHVKPSISLQHDHPEPTHPQPEPAPPLFGFQQWANNLRKSFSKGSNPVVLRRNRPMKARPLSEGSFNVGAVFQDEERCGSLVDEGEARPRTESEIASLLEQVALGSKTSRGTKDDMASLPPRKLNFFSSLRIKRVEGAEQSRGEGQKDILSILSRFRNKASAQQQQQQKSNSSSEDEQEPKLTHSGALQKKKEKIAIRQTKSDELKRLHRAQVIQRQLEEVEEKQRSLEEKGVALEKVLRGENGDDGSTDEAALLQTWFKLVLEKNKLSRYESELMIFAQELELEDTQSRLQQDLRRRMATEDCEKSASELVEEQNILVEIMKVVEKRDKLVSLLEEQRLKEKAEDRDLESLILSRGYQFHWT", "length": 1679 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1RXL1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152495", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFTICNDSHSDFILLGFSDKPYLEKILFWVVLIFYCLTIIGNLVIILVSLKDPKLHIPMYYFLSNLSLLDLCFTSSCVPQMLVNFGGPEKTISYIGCAIQLYVFLWLGATECVLLVVMAVDRYVAVCHPLQYTTIMHPKLCLELAILAWGTGLIQSLTQSPATLQLPFCSNRRLYDIVCEVPALIQVSSADTIYNEIQMSIASIILLVVPLVIILSSYGAITKALLRVKSTEGQKKAFGTCTSHLLVVFLFYGTVTAVYLQPKSHYAHEQGKFLTLFYTVITPTLNPLIYTLRNKEVKGALIRLGKKTWDDLCWTIA", "length": 317 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD0-1", "protein_name": "Transcription elongation factor A like 3", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRQVKHLRSGSLPTPGLSVTSPSPTARPATPRTACLFPALCKTRKGEGTCPESLQDKKRRKNLNMEKLCKENEGKPESEGKPEDEVEPDNEGKSDEEEKPEVEGKSAHEGKLQNEGQPEDEGKPEDEGKQEKQGKSEDEGKPPGEGTMESQAKPESEPRAAEKRPAEDYVPRKAKRKTDRVTDDSPKDYEEDLQERHLGSEEMMREGGDLSRAQEELRKRQKMGGFHWMQRDVQDPFTPRGPRGVRGMRGGGRSQRGLHDIPYL", "length": 264 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1RYD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110258723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "LLVVVLVTYLLTLVGNTVIILIASIDPNLKTPMYFFLTHLSLVDICLTTSIVPQLLWNLRGPAKTITTLGCAVQLYVSLALGSTECVLLAVMAFDRHAAICKPLHYAAVMNPRLCQALAGVAWLSGVGNALIQSTVTLWLPRCGHRRLHHFFCEVPSMIKLACVDIHTNEVQLFIASLVLLLLPLALILTSYGHIVKAVTRIKSVQAWRKALGTCGSHVMVVSLFYGTITAVYIQPNSSYAHTSGKFISLIYTVLTPTLNPLIYTLRNKDVKGAMRRLFRRDLGS", "length": 285 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S4M2-1", "protein_name": "Small ribosomal subunit protein uS13", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSLVILEKFQHILRVLNTTIDGWQKIAFATTAIKGVGRRYAHVVLRKADIDLTKRAGELTEDEVEHVITIMQNPGQYKIPDWFLNRQKDVKDGKYSQVLANGLDNKLHEDVERLKKIRAHRGLRHFWGLRVGGQHTKTTGRRGHTVGVSKKK", "length": 152 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S6C0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGNCLTPHTSEDLLVPASATHLGGRRRRARSRERRPRDQVPGWAPAAPLVQEEQVRVPQRISQIQCLPKGVYKRDGSQEKMEQEECAICTLDFVCGDPIRSLPCKHFYHLGCIDEWLTRSFTCPYCRGPADGPQPSSRDTP", "length": 141 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7I2-1", "protein_name": "Beta-defensin", "gene_name": "DEFB125", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MNLLLTFMICGLLTLVTKAGWNVERCWSYNIGHCRRRCLHLERYKHLCMNKRACCIPLSSDDPYTQWPLPPEDQTVGMKTPYFRPVSPGSELDDQITITITVDQESTGTEQDIEGTAISFQASTPIPENIEDTKFSDKANTLNLHKL", "length": 147 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1S7N4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100152708", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDQTNSSVVTEFVLVGLTQSLGMQFLLFLLFSTFYVGIILGNLFIVFTVISDSHLHSPMYILLANLSLIDLGLSSTTVPRMISDLFSDCKTISFHNCMIQMFFIHVTGGVEMVLLIAIAYDRYTAICKPLHYLTIMNPQMCMLLVVAAWITGVTHAVFQFAFVINLPFCGPNNVGSFYCDFPRVIKLACIDNYGLEFVVTANSGFLSTGTFFLLVVSYIFILVTVRQHSSKDLSKAFFTLSTHITVVFLFFLPCMFLYVWPFPTKSLDTFLAIVDFAVTPVLNPAIYTLRNRDMKVEMRRLSRQVISSREMT", "length": 312 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBB9-1", "protein_name": "DNA-directed RNA polymerase RBP11-like dimerisation domain-containing protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MHALPAFESFLLFKDEKITIHKDTKAPNACLFTIDKEDHTLGNVIKSQLLKDPQVLFAGCQVPHPWEHKIIVPVQTTPDYTPQEALLNVITDLISKLSLLEERLRVAIKDKQEGIECWTGRGPAWPGPALTLALLQAPCG", "length": 140 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SBV4-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100154723", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESENITVVTEFIFVGLTQSRNIQLLVFVLVFIFYLIILPGNFLIILTIRSDPGLTAPLYFFLGNLAFLDASYSFIVAPRMLVDFLSEKKVISYRGCITQLFFLHFLGGGEMLLLVVMALDRYIAICRPLHYSTVMNPRACYALSLAQWLGGFVHSIIQVALILHLPFCGPNRLDNFFCDVPQVIKLACTDTFVVELLMVFNSGLLTLICFLGLLASYAVILCRVRGSSSEGKTKAMSTCTTHIIVIFLMFGPGIFIYTRPFRAFPADKVVSLFHTVIFPLLNPVIYTLRNQEVKTSLKKLLINN", "length": 305 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SJ79-1", "protein_name": "Olfactory receptor", "gene_name": "LOC110259717", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEQNNGTKGTEFILLGFAGQHKSWPVLFIVFLVTYVVTLVGNIGMILLIKIEASLHTPMYFFLQNLEEKVDLCYATAITPKMLQNFVWTEHSISFIGCMVQLLTYGAFATSDCYILAAMAVDRYVAICNPLRYPTVMSQRVCIQLVIGSYFMGFLNASVNTSFTFQLNFCKSNKINHFFCDAPPILALSCSSIYFSIMLLAAFVGFNLTCTVSVVIFSYVFILAAILKISSAAGRKKAFSTCASHLTAVTLFYGTLSYMYLHHRTLESQEQEKLASVFYGIVIPMFNPLIYSLRNQDVREALKGVGKQCF", "length": 310 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SLL7-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRRENQSSISKFLLLGLPIQPEHQGMFFVLFLVMYLTTVLGNLLIILLIRLDPRLHTPMYFFLSHLALTDVSFSSVTVPKMLMNMQTQDQSIPYAGCVTQTYFFIFLACIDNLLLAVMAYDRYVAICHPLHYAIIMREELCLCLLVLSWLLSCAYALTHTLLLAQLSFCADIIPHFFCDLDALLKLSCSDTSLSELVTFTAGAAVVIFPFIGILVSYGHIGLSILRVPSTKGICKALSTCGSHLSVVSLFYRTSMAVYLSSSGQFHDKDIIVSVMYTVVTPMLNPFIYSLRNRDMTLALGILFRNINIFSK", "length": 311 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SMZ6-1", "protein_name": "10 kDa heat shock protein, mitochondrial", "gene_name": "HSPE1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAGQAFRKFLPLFDRVLVERSAAETVTKGGIMLPEKSQGKVLQATVVAVGSGSKGKGGEIQPVSVKVGDKVLLPEYGGTRVVLDDKDYFLFRDGDILGKYVD", "length": 102 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SRB7-1", "protein_name": "Large ribosomal subunit protein eL31", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVVQKSGEKKRGRSAINEVVTREHTTSIHKRIHGVGSKKRAPRALKEIRKFAMTEMGTPDVRNDTRLNKAVWAKGIRNVPRRICAPLSRKRNEDEDSPNKLYPLVTCVPVTTFKNLQTVNEDEN", "length": 125 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F1SUB9-1", "protein_name": "Multifunctional fusion protein", "gene_name": "IL1B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MATVPEPAKEVMANNGDNNNDLLFEADGPKEMKCRTQNLDLSPLGDGSIQLQISHQLCNESSRPMVSVIVAKEKPMNPSSQVVCDDDPKSIFSSVFEEEPIVLEKHANGFLCDATPVQSVDCKLQDKDEKALVLAGPHELKALHLLTGDLKREVVFCMSFVQGDDSDDKIPVTLGIKGKNLYLSCVMKDDTPTLQLEDVDPKSYPKRDMEKRFVFYKTEIKNRVEFESALYPNWYISTSQAEQKPVFLGNSKGRQDITDFTMEVLSP", "length": 267 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F2Z5L2-1", "protein_name": "Histone H2A", "gene_name": "H2AC18", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKQGGKARAKAKSRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYMAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGKVTIAQGGVLPNIQAVLLPKKTESHHKAKGK", "length": 130 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F4IWB9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 28", "gene_name": "CYP705A28", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIMGRSCSEKNGEAERVRGLVIESLALSPKIFLGMIFHKPLKKLGISLFQKDIKSVSPKFDELLEKFLVEHEEKMEEDHYKANDMMDLLLEAMEMRMQNVNLCIKRVSNTKARKPPILFRYGKYSNNSLLLQELLVAGTDTSALATQWTMAELINNPTILERLREEIESVVGNTRLIQETDLSNLPYLQSVVKEGLRLHPPASISVRMSQERCELGGFYIPEKTLLVVNTYAIMRDPNFWEDPEEFKPERFITSSRSEQEDEMREEVLKYIPFSAGRRGCPGSNLAYVSLGIAIGVMVQCFDWRIKGEKVNMSETAGTIMLAMAQPLKCTPVPRTLNLLPSSLHIPSS", "length": 348 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4J311-1", "protein_name": "Zinc finger (C2H2 type) family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLDGVELLLDLREMVSQSGFEKSTTCSGVIALRSNLQSKSSHKCKICGKSFECYQALGGHQRIHRPIKEKLSKQEFSEVYPRKSKLQKRPESSSSCYECKVCGKIFGCYRGLGGHTKLHRSTKRELASTQDENSLLDSSEAKKIVSQPSSFKVSQEEKFLHCVELKQDFSEPLSHSGALPSTLRSKLQTKTQWKSSCHCKICGKSFVCSQGLGNHKRVHREISGKLACKRKYTEDYNPFSDSLKAKKIVKKPSSFEVSQEEKILHCVELKQDFGELLAHSGFDKSISCSKSIKVKKVARKNEKTEDSTSLFGVFVGEMSQRLHGCKTCGRKFGTLKGVYGHQRMHSGNHNRIEDENGLERIWGLKKKSRVCSVSAFDRFKGSSFMAEIEKHEVIEAALNLVMLCQGVYDFASISNLPLGDGFMDLELKPCPLRRKLQKKSRSSYKCSICEKSFVCSQALGSHQRLHRWKLVPKPEYIEDDSSLLDSSEAKKIVSKPSSFEHAQEEKILQCVEPKLEFHEQLAHSGFDKFDTCSKIRFSALPSPPEAKKIVSQPPSFEVSVDEKILYRAEPKLNFSEPLAHSCFDNSSSYRSIICGKSFVCSQALGGHQTLHRSIKGQLAGTEDGNSLSVTDSEASKIVAQPSSYKSQGI", "length": 650 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4JLV4-1", "protein_name": "Protease inhibitor/seed storage/lipid transfer protein (LTP) family protein", "gene_name": "DHYPRP1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASTTIILFLSFSIIPLLTIVRADNHSVYCPPPPPCICICNPGPPPPQPDPQPPTPPTFQPAPPANDQPPPPPQSTSPPPVATTPPALPPKPLPPPLSPPQTTPPPPPAITPPPPPAITPPLSPPPPAITPPPPLATTPPALPPKPLPPPLSPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIIRNVSDLDAVTCFCKSVGAPRFSLSPNFGIFFKVCGRRIPQGFSCPGPSPTISPPPLPPQTLKPPPPQTTPPPPPAITPPLSPPLVGICSKNDTELKICAGILAISDGLLTTGRAEPCCSIVRNVSDLDAVTCFCKSVGARRFSLSPNFGIFFKVCGRRIPQGFSCP", "length": 375 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F4K5R6-1", "protein_name": "Cell division cycle 20.6, cofactor of APC complex", "gene_name": "CDC20-6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MMKSIALALCLTHHSPMVLSIVDYGDSQEKTIDSLWKKPHGSDLTWSGFSRVGVTEAYFAVPVDHFLTNPPSLRLSQTIYCRRGSSYVETEKVEEEDRDDFLKQVWFLTDNLVFFFVDIEEYIVIEQLGDTVYLWDASSCYTSKLVTIDDENGPVTSINWTQDGLDLAVGLDNSEVQVWDCVSNRHVRTLRGGHESRVGSLAWNNHILTTGGMDGKIVNNDVRIRSSIIGTYVGHTEEVCGLKWSESGKKLASGGNDNVVHIWDRSLASSNPTRQWLHRFEEHTAAVRALAWCPFQASLLATGGGVGDGKINFWNTHTGACLNSVETGSQVCSLLWSKSERELLSAHGFTQNQLTLWKYPSMVKMAELNGHTSRVLFMAQSPDGCTVASAAGDETLRLWNVFGEPPKTTKKAASKKYTEPFAHVNHIR", "length": 428 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "F5H284-1", "protein_name": "Peptidyl-prolyl cis-trans isomerase A-like 4D", "gene_name": "PPIAL4D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVNSVVFFEITRDGKPLGRISIKLFADKIPKTAENFRALSTGEKGFRYKGSCFHRIIPGFMCQGGDFTRPNGTGDKSIYGEKFDDENLIRKHTGSGILSMANAGPNTNGSQFFICAAKTEWLDGKHVAFGKVKERVNIVEATEHFGYRNSKTSKKITIADCGQF", "length": 164 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "F6R3J9-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1G", "gene_name": "Speer1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNKKNKEVEIDWALIEKYLVDLNLNGQTGADQQP", "length": 157 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6X687-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1A", "gene_name": "Speer1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKQSSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMPVTQNQKNKEVEIDWALIEKYLVDLNLNGRTGADQQP", "length": 157 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6YNI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRCRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILVGLQDYQDNKADVILKYNLDEARSLKAYGELQEHAKINETDTFGPGDDDEIVFDDTGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7AMQ8-1", "protein_name": "Exocrine gland secreted peptide 8", "gene_name": "Esp8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKVSAMTSFPVMLFLIILLLPSICSEERTQADPTISADNKKNFKTVVDLTDCQCERNFIESLESTLPASNQDQTLFENMTNQHKLNLSKMLSVLSKCCTQKQQVDTVHFRRMPHRIQSTKQNNYKKQVLYPMQEFMNLTRDVLVSRYV", "length": 149 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7C9P2-1", "protein_name": "F-box and WD-40 domain protein 25", "gene_name": "Fbxw25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEIHLPSLPMLKILSYLDAYNLLQAAQVNKNWNALASSDVLWRKLCQRRWHYCDMVTLQLQGKETWKQFFIYRIWQEHAKTRAKPEDFTYKEIPVECGFYGYACYISGHGLTRNGQGKSVICMVSSKNTISTWDIHKSVITWVSPVQPASINLLTTLPDMHIAVTVDIQSTIKLWDCHNREALATNNLESPCKSLKAVISKDGPIVLVGDTLGNLYIFRIPDLHLISTVNVFPYGFDEIDCSPQKKWVLLSKNYPHILPKVFYMSSLLRTSEFSAPVSTILEFSLCQGAFWTPRREDRITLMSRSGFPQITKFETFDMKLEGIGNKVAVQGKLIASFFLPYYEESPNWIGVSDKDVIVCSTHFFLLLFTINGLHLQTFQYCPETIVRLCVDPVHVIVTCNNGSLDVYAWEERSLLLRKCYRLQNKRPLPLYGFINNLLCDDVSIVQLMRDGHGPYSLIAYALNICS", "length": 466 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7ELE5-1", "protein_name": "NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial", "gene_name": "Ndufs7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRTVVYTARARSQEKSGSEPLSLWFRFPLVSIWALDQNRNSLEDGPQRLSEGRGQDGGAGGSWLALCTDPGSAHRHSGSAAQSPPECGSHWEPEQSAVSKAGAGAVVPKPSHLPRSRAEYVVTKLDDLINWARRSSLWPMTFGLACCAVEMMHMAAPRYDMDRFGVVFRASPRQADVMIVAGTLTNKMAPALRKVYDQMPEPRYVVSMGSCANGGGYYHYSYSVVRGCDRIVPVDIYVPGCPPTAEALLYGILQLQRKIKREQKLKIWYRR", "length": 271 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F947-1", "protein_name": "Beta-defensin-like domain-containing protein", "gene_name": "Spag11b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLSQRPPNVFRHVVDFLKKNQTHITQACSGNSGGRKASSSDLCGCALCLEAPSPHSQLSYKRACSSCPPTRGSSVPAVPSTAMKQRLLPSFVNLLLAALLLPGKAETWLRSWTQALSAVVTLGSSSASSINHLVTEPPSSPQDEFPAQGGNGSGLLHHRVKRFPPRTPPYHEPGPNYQIVNCKKNEGFCQKYCNFMETQVGYCSKKKEACCLHPF", "length": 216 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7FNC4-1", "protein_name": "Interleukin 36, gamma", "gene_name": "Il36g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSKYPHSPCTASGKETPDLGQVSDVDQQVWIFRDQALVTVPRSHTVTPVTVTVLPCKYPESLEQGKGTPIYLGIQNPDKCLFCKEVNGHPTLLLKEEKILNLYHHPEPMKPFLFYHTLTGATSTFESVVFPGSFIASSKIGKPIFLTSKKGEHYNIHFSLDII", "length": 164 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F8VPX6-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 4A1", "gene_name": "Speer4a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVNGRETREGRKDANLPPESNEGRRRWTWRMWMAHRQTTSSVPVTSKKQFEKEEKELIKKIQLTTKETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHNLEMENMEARENKQEFKKEKNFYRNLHTRILLEENLIKKKLAILQQESKEIHADWAIIQERLVELNLSCKDEQEKTSNLETQENQVSEAARELGLATAEEDSILQNELPCQEAPAEHHTQNPPSSSDESSSDESSYSTCPAWE", "length": 267 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F8VQM2-1", "protein_name": "C-C motif chemokine ligand 26", "gene_name": "Ccl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFDLGLLVLLAIFLSVQLGVATCGSSIAMSCCPNFSYYVIPWSWVYSYKFTDKSCTSDGVIFFTKTGKQFCVQPGAKWVQRFISLVNTRNHL", "length": 93 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3GSG1-1", "protein_name": "Ferritin", "gene_name": "LOC100767129", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGFLRKSHRRQRHRCPLRVSRATVAYPLVFMTPPIISPPSQVRQNYHFDCKTAVNNHVQLQLHNSSVYLAMAFYFDSEDVAQKNLASFFLNKSHECTAQAEMFLELQNQRGGRISLGSIREADRNNWLGGLQAMECALQLELSTNQSLVALHQLASSKSDAHLCSFLKNHFLTKQVEVLKEISGYVTKLRQMGSPDDGIAEYLFGKLTLDDNKGK", "length": 215 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3GWA3-1", "protein_name": "60S ribosomal protein L18a", "gene_name": "LOC100764432", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MKASGTLREYKVVGRCLLTPKCHTPPLYLMRIFALNHVVAKSRFWSQLKKMKSSGEIVHCGEVRPEVPLQVKNFAIWLHYDSRNGTYNMCREYWDLTVTQCYRDMGAQHCARTHCIHIMKVEEIASGKCQRPAVKQFHDSKIKFLLPHRVLRCQHKPHFTTKRLNTFF", "length": 168 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H156-1", "protein_name": "Prefoldin subunit 4", "gene_name": "LOC100773780", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVATMKKAAAEDVNVTFEDQQKINKFARDTSRITEQKEIEVKKNHLQNLEDTFNDIMLADGDCFMTQYLIRDVLISHSQEEAQEMLEEAKKTLQEEIDALESRVGAIQWVLANLKVQLYTKFGSNINLGVDES", "length": 133 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H2T6-1", "protein_name": "Histone H4", "gene_name": "LOC100757199", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3H8X2-1", "protein_name": "1-acyl-sn-glycerol-3-phosphate acyltransferase gamma", "gene_name": "Agpat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGLLAYLKTQFVVHLLIGFVFVVSGLVINFTQLCTLALWPISKQLYRRINCRLAYSLWSQLVMLLEWWSCTECTLFTDQATVDHFGKEHAVIILNHNFEIDFLCGWTMCERFGVLGSSKVLAKRELLCVPLIGWTWYFLEIVFCKRKWEEDRDIVKEGLQCLSDYPEYMWFLLYCEGTRFTETKHRISMEVAASKGLPPLKYHLLPRTKGFTTTVQCLRGTVAAIYDVTLNFRGSKNPSLLGILYGKKYEADMCVRRFPLEDIPADENDAAQWLHKLYQEKDALQEMYKQKGVFPGEPIKPARRPWTLLNFLCWATILLSPLISFVLGVFASGSPLLILTFLGFVGAASFGVRRLIGVTEIEKGSSYGNQELKKKE", "length": 376 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HAB3-1", "protein_name": "40S ribosomal protein S15", "gene_name": "LOC100759804", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEVEQKKKRTFRKFTYCGVDLDQLLDMSCEQLMQLCSTRQRLLLNCSLWRKQHSLLKSLRKAKKKVPPMEKPEVGKTHLRDMIILPEMAGSMVDVYNGKTFNQVEIKPKMIGHYLGEFSITYKPVKHGGPGVGATHSSRFIPLK", "length": 145 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDI6-1", "protein_name": "Lipid transferase CIDEB", "gene_name": "Cideb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEYLSALNPNGLLRSVSTMGSELGRRVWNSGPPPQRPFRVCDHKRTVRKGLTAATRQELLDKVLETLLLSGVLTLVLEEDGTAVESEDFFQMLEDDTCLMALERGQSWSPRSGMLSYGLGREKPKHSQDIARITFDVYKQNPRDLFGSLNVKATFYGLYSMSCDFQGVGPKKVLRELLRWTSSLLQGLGHMLLGISSTLRHVVEGAERWQWHKQNHLRS", "length": 219 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HDS5-1", "protein_name": "Histone H3", "gene_name": "LOC100773314", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HGI3-1", "protein_name": "PHD finger protein 6", "gene_name": "Phf6", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSSIEQKKGSTRQRKCGFCKSNRDKECGQLLVSENQKVAAHHKCMLFSSALVSSHSDNESLGGFSIEDVQKEIKRGTKLMCSLCHCPGATIGCDVKTCHRTYHYHCALHDKAQIREKPSQGIYMVYCRKHKKTAHNSEADLEETFNEHELEPSSPKTKKKSRKGRPRKTNFKGLTEDSRSTSSHGTDEMESSSYRDRSPHRSSPNDTRPKCGFCHVGEEETEARGKLHIFNAKKAAAHYKCMLFSSGTVQLTTTSRAEFGDFDIKTVLQEIKRGKRMKCTLCSQPGATIGCEIKACVKTYHYHCGVQDKAKYIENMSRGIYKLYCKNHSGNDERDEEDEERESKSRGRLAIDQQLTQQQLNGN", "length": 364 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HJW3-1", "protein_name": "Calcium homeostasis modulator protein 6-like", "gene_name": "LOC100774768", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEKFKAVLDLQSKHRSALGYGLVTLLTAGGEKIFSEVVFQCPCSATWNLPYGLVFLLVPALALFLLGYALRTRTWRLLTGCCSWSASAQSSSGLQRVFVCAQISAAAALPPLTWVAVALLGGSFYQCAVSGSEAMARHLCKGRDPSCAAKLPQVPCKKQEAEMQDILSQLKAQSQVLGWILIAAIIILLLVVKSVTRCLSPVSYLQLKFWEIYLEKERQILQGEAMEHATQLAKENVRCFFDCTNPKDCSTPSSKAWQQISALYTFNPKNHFYSMLHKYVNRKDMSGSLRSVEGDAVVPVLGFVDASGMATTHGV", "length": 315 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQ40-1", "protein_name": "Eukaryotic peptide chain release factor GTP-binding subunit ERF3B", "gene_name": "LOC100767578", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MDLGSSSDSAPDCWDQVDMEVPGSAPSGDGFTSASTAAAEAAEAEAQRQHLSMAFSSQLNIHAKPFVPRVSAAEFVQSFLPGSAQPPAPTTSSSDETCTGAGDPQGKRLGWGAPVEPSKDGPLMSWEGSNSAVTMELSEPVVENGEVEMALEESWELKEVSEAKPGGSLGDSGPPEESGKEMMEEKEVIRKSKSMAIPSGAPKKEHVNVVFIGHVDAGKSTIGGQIMFLTGMVDRRTLEKYEREAKEKNRETWYLSWALDTNQEERDKGKTVEVGRAYFETEKKHFTILDAPGHKSFVPNMIGGASQADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKYLIVLINKMDDPTVDWSSERYEECKEKLVPFLKKVGFSPKKDIHFMPCSGLTGANIKEQSDFCPWYTGLPFIPYLDSLPNFNRSIDGPIRLPIVDKYKDMGTVVLGKLESGSIFKGQQLVMMPNKHNVEVLGIVSDDAETDFVAPGENLKIRLKGIEEEEILPGFILCEPSNLCHSGRTFDVQIVIIEHKSIICPGYNAVLHIHTCIEEVEITALISLVDKKSGEKSKTRPRFVKQDQVCIARLRTAGTICLETFKDFPQMGRFTLRDEGKTIAIGKVLKLVPEKD", "length": 631 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HQN5-1", "protein_name": "Transcription factor 19 isoform X1", "gene_name": "Tcf19", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLPCFQLLRIGGGRGGDLYTFHPPSRSGCTYRLGCRADLCDVALRPQQEPGLISGVHALLHAELQGDDWRVSLEDHSSQGTLVNNVRLPRGHRLELSDGDLLTFGPEGQAGTSSSEFYFMFQQVRVKPQDFAAITVPRSRGEAGTGFQPMVPSQGAPQRPLSTLSSAPKATLILNSIGSLSKLQPQPLTFSRGGGRPQSLAVPTQPGEVGASPPAPPTRNRRKSVHRVLAELDDENETSLSPLSVLMEPRKKLRLEKAALVSSGRD", "length": 266 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3HWQ5-1", "protein_name": "Zinc finger protein 219", "gene_name": "Znf219", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEGSRPRILVGHLEPSPPAFDGELDLQHYSNGPGVSTGSPGMGAVGWSETRAGERRFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLLELEERALLREAQLGRARSSGGMQATPATEGLARPQVPSSSAFPCPFCKGKFRTSAERERHLHILHRPWKCSLCSFGSSQEEELLHHSLTAHGASERPLAATSTPEPQPPPQPEPRSALEPEPEPEPRPEPEHEANPAPTPAPPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPWFLKNHMKVHTSKLGPLRAPGPGSTPARAPQPPDMSLLAYEPLGPALLLAPAPTPAERREPPSLLGYLSVRAGEVRPNGEGADPGAGRSYGGGFRPLPSALPNRARRHRTEEPEEEEEVVEAEEESWARGRSLGTLTSLHPHPGEGSGQSAPAVGAQARPTGTQEENGLLVGGARSEAGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHREQRSSAGPGPPPEPPPPSPRGAASLQPQSGAKPTQASATWVEGTASTRPSSSGTGAGSRRKPASPGRTLRNGRGGEAEPLDLSLRAGPGGEAGSGGALHRCLFCPFATGAPELMALHLQVHHSRRARGRRQPRADTSPPYVRAPSGETPPSPPLEEEGSPGLSRSGEAGLGGQER", "length": 725 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I071-1", "protein_name": "Large ribosomal subunit protein uL29", "gene_name": "LOC100753244", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAKIKARDLRGKKEELLKQLDDLKVELSQLRVAKVTGSAASKLSKIRVVQKSIVRVLTVINQTQKENLRKFYKGKKYKPLDLRPKKTRAMHRQLTKHEEKLKTKKQQRKERLYPLRKYAFKA", "length": 122 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3I1Z3-1", "protein_name": "DNA damage-inducible transcript 4 protein", "gene_name": "Ddit4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPSLWDRFSSSSSSSSSSSSGTPATDRPPRSAWGSAAREEGLDRCASLESSDCESLDSSNSGFGPEEDSSYLDGVSLPDFELLSDPEDEHLCANLMQLLQESLSQARLGSRRPARLLMPSQLVSQVGKELLRLAYSEPCGLRGALLDVCVEQGKSCHSVAQLALDPSLVPTFQLTLVLRLDSRLWPKIQGLLSSANSSLVPGYSQSLTLSTGFRVIKKKLYSSEQLLIEEC", "length": 231 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IAH8-1", "protein_name": "Guanine nucleotide-binding protein subunit gamma", "gene_name": "LOC100755128", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MASNNTASIAQARKLVEQLKMEANIDRIKLSKAAADLMACCAAHAKEDPLLTPVPASENPFREKSFCTIL", "length": 70 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IG76-1", "protein_name": "Olfactory receptor 7E24 isoform X2", "gene_name": "LOC100765597", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MYILALFGNLLIILTVSSDSHLHTPMYFFLSNLSMIDIGYISTTVPRVIVDIQTHCPVISYVGCLTQMSLIIIFACMDDMLLSVMAYDRFVAICHPLYYQVIMNPSSCGVLLLGSFLLSLVNLLLHYVAVLSFSNCEDIFEISNFFCGPSELFKLACFDTFTTNIVRYCAGALFGLLPISGIIFSYFKIVSSIMRSSSSSNGKWKTFSTCGSHLSIVCLFYGTALGMYFSSSLSLSPKTNAVASVMYTVVTPMLNPFIYSLRNKDIKTALRKILSRTF", "length": 278 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3IGD7-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100770882", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSGANSSSLTPEFFVLNGIPGLEDAHVWISLPFCFMYMIAVVGNCGLMYLIGHEEALHRPMYYFLTLLSFTDITLCTTTVPNTLCIFWFNLKKIGFKACLAQMFFVHTFTATESGMLMLMALDRYVAICYPLRYGTILTNPVIAKASLATFLRSVAFILPFTFLTKRLPYCRGNTIPHAYCDHMSVAKISCGNVKVNAIYGLLVALVVCAFDIFCITVSYTMILRAVMNLSSADARHKAFSTCTSHICAIVITYVPAFFNFFTHRFGGHTIPHHIHIIVANLYLLLPATMNPIVYGVKTKQIRESVIKFFSGDKSGITEIKGLQNK", "length": 326 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3INQ1-1", "protein_name": "Olfactory receptor", "gene_name": "LOC100763177", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MFCNTSTPGHSTFLLTGFPGLEASHHWVSIPINLICVVSILGNSIILFLIRTDPALHEPMYIFLSMLAASDLGLCASTFPTMVRLFWLGIRELPFDLCAAQMFFIHAFTYVESGVLLAMAFDRFIAIRDPLHYATILPHSAVAKVGAAVLIRAILLNLPGPILLRRLLFPQVSVLSHCYCLHCDLVGLACSDTRINSLVGLVSILLSLGLDSSLIMLSYVLILRTVLSIASPGERLKALNTCVSHLCIVLIFYLPKLGLSVLHRVEKHSYPALAVLMANLHFLVPPFMNPVVYCIKSKQIRQGFLKRFQQKRVDVS", "length": 316 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G3MYE2-1", "protein_name": "Large ribosomal subunit protein uL18", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGFVKVVKNKAYFKRYQVKFRRRQEGKTDYYARKRLVIQDKNKYNTPKYRMIICVTNRDIICQIAYARIEGDMIVCAAYAHELPKYGVKVGLTNYAVAYCTGLLLACRLLNRFGMDKIYEGQVEVTGDEYNVESIDGQPGALTCYLDAGLARTTTGNKFFGALKGAVDGGLSIPHSTKQFPGYDSESKEFSAEVHRKHIMGQNVADYMRYLTEDEDAYKKQFSQYIKNNVTPDMEEMYKKAHAAIRENPVYEKKPKKEVKKKRWNRPKMSLGQENDRVAQKKASFLRAQERAAES", "length": 295 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3MZM9-1", "protein_name": "Uncharacterized protein", "gene_name": "LOC107131211", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTRAEFKQTKLQELRRRLLIIVIGTLITGYMVTCTCLLHYRCDSKEAHKAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKLVSQVSPSYPEKAIKPTWPPSLQCRVKPTKTPLPYPKNQSFPEHSSADKLTKRQRYLKLKCPASAGRAEILSRPQPVKFCRCYKEKCLVCRAVSEPFITHVSEANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSPNN", "length": 361 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3UW31-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r176", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVTLQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQFVTLAPGTWGRVMLPGRAPNFLRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDSNSKSKWVCSTSGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFVDSRVWLRRVKEILSVSFPTFSPLLLIFRDPKDPCSLLFGC", "length": 304 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UY92-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r158", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQLLLLCQFGVGTVAKVFLFVRNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVARSTNLCSTCVLSFHQFVTLVPLNRGKGKLVLRASVTNMASYSSYSCWFFSVLSNIHIPIKVSGPQIKDNNTDSNRKLFCSTSGFSVGTVLLQFAYDATFMSIMVWASVSMVLLLHRHRQRMQHILTPNQDARGQAESRATRTILMLVVTFVSFYLLNFICIMLHALFMHSHFFVRLVSEILTAVFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V9M0-1", "protein_name": "Cystatin S like 1", "gene_name": "Cyssl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACLLYTQLFLLNTFILFLNLSLNPVLGQILAGIEKSIIEEEGALEALNFAVSEYNENNSDLYLSRVVEVKTVKTVQQQIEAGKTLLFDVILGKTACLKTQDDLSDCPLNEPTDLQEREFCSFEVHLPDWANAINLLSSICNRI", "length": 144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X693-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "RVFLPLLLLGVILPGGDNEDGPTSFHLIQISTFVNNTWAQNQGSGWLDDLQIHGWESDSGTAIFLKPWSKGNFSDDEVTELVDLFRAYFIGFTREVQDRVNEFQLEYPFVIQVTAGCELHSGEAIESSLRGALGGLDFVSIQNHSCVPAPDGSSRGQKFCALTTQYQGISDIIERLLSETCPRYLLGVLDAGKAELQRQVKPEAWLSSGPTPGPGRLLLVCHVSGFYPKPVRVMWMRGEQEQPGTQQGDLMPIGEAAGLNCRVKHSSLGDQDIILYWGHPTSIGLILVAIIVPSLILLICLAFGVLRFMGSHRIGHD", "length": 317 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3X9Q9-1", "protein_name": "Predicted gene 6526", "gene_name": "Gm6526", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGDQGETRPRQKESAIPSCKKRRMKSFWGRHMSAGKKSSQNCNITNHMKNMNKLEDMKFYIRKINAKRLELFPILDIDMNTDLNYRMNIEFTIIKSQHEKTMLDMEKMTQSISDTIETYKEFIEDKDSYSFTHSYLLKECNQLKEKVRMLLNENRKLLVEQADQEASYGEEKRFCDESSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8X8-1", "protein_name": "Oocyte maturation, alpha", "gene_name": "Omt2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLVFTKVHLESWVYKGLRGQHDSILELLKENLHHYLCIEFDEGLNDTVVYIIGFKFFAMFAMFVIVSLACNLRTKRNRARAWARGLQSPVWWNRRYFI", "length": 100 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ46-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLSFMSSLLENILYFQAGLGVLANIFLLVFYIFIILGHRPKPMDLISCQLTFVHIMMFLAGENFWLANIFESLNVENDFKCKATFYTKRVMRGLSICITCLLSVFQAVMISHRNSLLAKFKHKLKIYMINALFYIWTFNLSLSSNLIFYVGGFTNMSQTKQLKVTKSCSLIPMNYIIRGLILTVISSRDMFLVGVMLTTSTYMVIILCRHQRQCKHLHSTSHLRASPEKRATQTILLLVVFFVIMYWVDFIISSTSILLWMYDPVIMIVQKFVVNAYPAITPFVQISSDTRVIRVVKNWHS", "length": 303 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BJ88-1", "protein_name": "Vomeronasal 2, receptor 3", "gene_name": "Vmn2r3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMAIRKKCLILELTVFLCVELYAQYEDQNMTCRLMRKFNLTGYVEAENHHFVIGGQFPVHYRTIPTSDSDEEPESPMCEGFNFRGFRWMKTMIHTIKEINERKDILPEHTLGYQIFDNCFSTTKAMESSMVFLTGQDEYKPKWRNSTGKYLIGIIGAGGSTMSLAGARILLLNDVVQVGYASSSSILTEYLNVYRTIPSDKFQTEAIVNLIRHFGWVWIGAIASDDDYGKHGVKSFRKILETNNLCIAFSETIPKVYSNEKMQIAIDAVKSSTAKVIVLYATDFDLSPFVLEVIHHNIAHRTWIATEAWITSALIAKPEYFPYFGGTIGFAIPRSVIPGLKEFLYDVHPSKDPNDVLTIEFWQTAFNCTWPNSSVPYNVDHRVNMTGKEDRLYDMSDHLCTGKEKLKDLKNTYLDTSQLRITNNVRQAVYLMAYGLDRLIRVLIKEYREYLLHPKILAFMSYKLFEYIRKVKFTTHDGRKIELNVHGDIENGYYDILNWQMDNTGDIAIVKVGEYKFTRSKYELVLPKNSTLFWNTESSRLPDSVCTKVCPPGTRKGFITGQPVCCFDCIPCEDGYVSEKPGQRLCNPCSEDDWSNAEKNKCVPKHVEFLAYEEALGFTLVILSIFGALVVLAVTVVYVIHRHTPLVKANDRELSFLIQISLVITVLSTMLFIGKPCNWSCMARQVTLALGFCLCLSSILGKTISLFFAYRISISKTQLISMHPSFRKLIVLLCVFGEIGVCASYLVLKPPSMFKNIERQNVKIIFECNEGSVEFLCSIFGFDVLLALLCFVTTFMARQLPDNYYEGKCITFGMLFFFIVWISFVPAYLSTKGKFKVAVEIFAILASSYGLLGCLFLPKCFIILLRPKRNTDETVGGRVPTVDRSIQLTSASVSSELNSTMVSTVLDE", "length": 909 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BKT1-1", "protein_name": "piRNA-mediated silencing protein C19orf84 homolog", "gene_name": "Gm52993", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDELEDGALSNGDNLSLPSAGTESWPTSATPGLPPSLLSTLDPTHLGLPEQLASVTVPIRLDTLSYLLHSALLGTYNLQQSLPPCSCTAQPSHIWPDTVRRPPRRSGQARGGWEVRRRPSRGWGRGRGRGRVWAQSQRGPERAEERERNMAGEPGAGPSTPPVTPPSQDGQKEAGGLSEDWEADY", "length": 185 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "H3BLP0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLTNILYFQAGLGILANTFLLCFYTFTILCHRSKPMDLTSCQLTLAHILFLLAGGDNWLAVILESLNIENDFKCKAIFYTNRVMRGFSICITCLLSVFQAVTISPHTSLLAKFKHKLKTYIIYAVFYIWFYNFLVCSHLLVYVGGFNNVSETNQMRVTESCSLFLMNYIISGLIFTVTTFRDVFLVGVMLITNAYIVIILFRHQRHCKHLHSIRHLRVSPEKRATQTILLLMVFFVVMYWVEIIISSTSLLLWMYDPGFLTVQKLIVTVYPTITPLVQISSDKRVINVLKNLQSKCQQIF", "length": 302 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3ITL1-1", "protein_name": "Gap junction protein", "gene_name": "gjc4a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWDFLTHLLDEISNHSTFVGKIWLTLLIVFRIVLTVVGGETIYDDEQSEFVCNTLQPGCKNVCYDAFAPLSHVRFWVFQIIMISTPSVMYLGFAMHKIARMADNEYQPRKHKMLSTVHQRMNRDYDMVDEMTEEVPMIPEEIEPSEKDNKSAASTKTTAASDAAVKHDGRRRIKRDGLMKVYVLQLISRVAFEIAFLFGQCILYGFEVSPSYICTRSPCPHTVDCFVSRPTEKTIFLLIMYVVSVLCLALTVLEILHLGIGGLRDSFRSRANRRLPVHRPSTSTICHRLSSAPPGYQAVQKKYSSGKLKAEFLSDSGRESLADDNTTRDLDRLRRHLKIAQQHLDQAYHTEEVGASHNSGPDSKSIAAEQNRLNQAQGGFGSTEEKVFKEAHA", "length": 394 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I3L8A5-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "FPSRQERTMRRENQSSISEFLLLGLPIPPEQQGVFFALFLGMYLTTMLGNLLIILLIRLDPRLHTPMYFFLSHLALTDISFSSVTVPKMLMNMQTQDQSIPYAGCVTQMYFFMFFACLDNFLLTSMAYDRYVAICHPLRYTSIMRGGLCTLLVTVSWILSCANALCHTLLLAQLSICAENTIPNFFCDLGALLKLSCSDTSFNDLAIFIAGVATIMLPLLCILVSYGHIGATILKIPSTKGICKALSTCGSHLSVVFLYYGTIIGLYLVPSSSTSSHKDIVASVMYTVVTPLLNPFIYTLRNRDMKGALEKLFHKAPVLS", "length": 320 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3L8Z8-1", "protein_name": "LRRC37A/B like protein 1 C-terminal domain-containing protein", "gene_name": "LOC100514982", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MMTLELEKLILPSHMACCLCQFKSNIEVVCKTVKLHCDRCLKNSTRCDKETSLGDVEGSFMKVLQARKKNTSTELMIEPERPSSDKSGVSLSSFMNEQLDFSDESDVISALNYILPYFSEGNLEDVESTLLPFIQLLFSNVAEADIPPGHLKTHTGNPPVNPESGTSGYTNKLRQLRFLENLLDAEIQEKIDEVMKKEKTAMLIYSNILSPKLRRQILRKKLETARTQAESLEEIESVDKRPLKVNRVLKGPRGIKKRHFRAMRRQSIRRKETAQPFVETTTKGSKLGGPSARELEQLWVVQRPRKRVADSLQKEPSFGREHKAEVSSFLKQYSRGRPAASIHPKAPATVKKTSEDLSDTLFVLVDANARVKNRKASETISYPRKIDSFHPSHSPVLHRTPEPQNRQAFRDKGSSYRLLLALRPLSSAVRSLINSPSQEASSPSGELTLQEQPSPESFSPSEPSTEHIISEKDTPQVVFEELPTSGTTTLSGPIPGPTAQGTLPTEYSATTADNVMPTGQHTSAIQWEHHNVGTDVASTPTSFISPGVSSPGSQFEAQLNQQLQSLIPNNDVRRLISHVIRTLKMDCSEPQVQLACAKLISRTGLLMKLLSEQQEAKASKAEWDTDQWKTENYINENTEAQGEQKESSELTKDVPGYGYNNKLILAISVAVVLMLLIVILCLIEVYSRRRTLREGKVGRRRGFFGFLLRKRRSGESESEGFFWRRRPLWLRDTYRPLSATRKKNMAEKLHDKESSDEEEIFHKGAGEVSEAPADVILTIESDVEDLGEETDTAPEGPPE", "length": 799 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LBH4-1", "protein_name": "Large ribosomal subunit protein uL11", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPPKFNPNEIKAMYLRCTSGEISAKSALAPKIGPLGLSPKEVGDDIAKAAGDWKGLRITVKPTIQNRQAQMEVVPSASALIIKAPKELPRDRKKQKNIKHSGNITFDEIVNIARQMRRCSLARELSGTIKEILGTAQSVGCNVNGRRPHDIIDDISSGAVECQAS", "length": 165 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LC12-1", "protein_name": "Olfactory receptor", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFGANLTIFHPTVFILLGMPGLEIYHTWLSIPFCLMSIVAVLGIGALILVVLSESTLHEPMHVFLSMLAGTDNLLSTTTVPKALAIFWFHAGEIAFDACITQMFFIHVAFVAELGILLAMAFDRYVAICALLRYTAVLTPSTIVKLTLAIWGWGIGTIFPIIFLLKRLPYCRTNIIPHSYCEHIGVARLACADITVNIWYGFSVPMASVLVDVAFIAVSYTLILQAVFRLPSQDAQHKALNTCGSHIGVILLFFIPSFFTFLTHRFGKNIPHHIHILLANLYVLIPPMLNPIIYGAKTKQIRDSLAHMLSRVGMS", "length": 315 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "I3LEQ2-1", "protein_name": "All-trans retinoic acid induced differentiation factor", "gene_name": "ATRAID", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARPGFRSPSSLVPRAAALLLVLSVPRALALPEICIQCPGDVQNLSEVALYCKQTPELMLQGRCCLNGKGTILGLDLQNCSLKDPGPDFAQAHTAVIIDLQANPFEGDWANTFRGFTQLQTLILPQGVNCPGGINAWDVVTFYITNQTCQGQRTFATALGTQKRVLRMDLVLLMVLVSCSVFVLMASMATSVCARAHSHCSCSSVFWDPQHYPFPSCFGGLNAEKPRLHEPQRSSY", "length": 236 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "J3QM75-1", "protein_name": "Secretoglobin, family 2B, member 19", "gene_name": "Scgb2b19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLITGELSFQTTEACVPFFEGYASVVSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLNNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMG8-1", "protein_name": "T cell receptor alpha variable 13N-3", "gene_name": "Trav13n-3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKRLLCSLLGLLCTQVCWVKGQQVQQSPPASLVLQEGENAELQCTYSTTLNSMQWFYQRPGGRLVSLLYSPSWAEQRGGRLTSSAASNESRSSLHISSSQITDSGTYLCAME", "length": 112 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QML3-1", "protein_name": "BTB domain containing 35, family member 29", "gene_name": "Btbd35f29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHQGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKKVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDALTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMQ9-1", "protein_name": "Predicted gene, 20873", "gene_name": "Gm20873", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRESSSNTLRNIVGRRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYLVKYDGIDSIYGLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFEGKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPGLYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANLSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMS5-1", "protein_name": "BTB domain containing 35, family member 2", "gene_name": "Btbd35f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEDIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKKVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW5-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADIILKYSPDEARSLKAYGELPEHAKINEMDTFGAGDDDEIMFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QMW9-1", "protein_name": "BTB domain containing 35, family member 6", "gene_name": "Btbd35f6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLSCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYRDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLQTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QN64-1", "protein_name": "BTB domain containing 35, family member 22", "gene_name": "Btbd35f22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDMKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYIDNISFLESEEGLIFQPVFKKLRFQHIIWDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYNEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QNQ5-1", "protein_name": "BTB domain containing 35, family member 24", "gene_name": "Btbd35f24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEGIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKDTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIIYDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP08-1", "protein_name": "Histone H2A", "gene_name": "H2al1k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKKMQRRRRQKRTRSQRGELPLSLVDRFLREEFHSSRLSSSALSFLTSVLEYLTSNILELAGEVAHTTGRKRIAPEDVRLVVQNNEQLRQLFKPGGTSVNEDDN", "length": 105 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP87-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLEAMCFDGVRRLCNIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNQDEARSLKAYGELPEHAKINETDTFGAGDDDEIVFDDIGDEDEDIDDI", "length": 144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QP96-1", "protein_name": "PRAME like 3C", "gene_name": "Pramel3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDTKDPPTLLDLATQSLLSNEHAAIQALEEIPRELFVPLFTAAFTGRHKNILTAIVKAWPFACLHIGALSVQEPERELLKALIESLQFLPALNSATRSPKLRILDLRQDAGCKTVCPDISTNSTICFRSCAHSEHSIFKIEGQESLSSSKSEAQPSRLPMELIVDISLDGTLRERNFFALLQNKVEQSLGSLHLCCRDLQINNLCECRHALSHLDLKCVDHLAVDESPLTEVTKLLSHTIQLDSLSLSKIACRSLNGRTFRNFITQLSRMNHLKELSLSSFCLTDHLETVLRVLSADLEFLYLPFCGLSYSDFKFLSECSQVSHLKLLNVNNNPIYWEDCEPFYYLLQNVSSTLQHLKICYCFLTDSTISVLIPALTRCSQLRVLHFYSNQITMGMLMRILELLTPLKELKHVIYPIPVHCYGRWHFQGSLDRQKVEDVQRQLNLMLQEAERSDMNWITYSD", "length": 463 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QPI8-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGWLEAMCFDGVRRLCHIRGKLTKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGAGDDDQIVFDDIGEDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "J3QQ02-1", "protein_name": "Eukaryotic translation initiation factor 4C", "gene_name": "Eif1ad11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKNKGKGGKNRRRGKNENESEKRELVFKEYGQEYAQVTKMLGCGRLESMCFDGVRRLCHIRGKLRKKVWINTSDIILIGLRDYQDNKADVILKYNPDEARSLKAYGELPEHAKINEMDTFGPGDDDEIVFDDIGDDDEDIDDI", "length": 144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7GP63-1", "protein_name": "Large ribosomal subunit protein eL39", "gene_name": "RPL39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSHKTFRIKRFLAKKQKQNRPIPQWIRMKTGNKIRYNSKRRHWRRTKLGL", "length": 51 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "K7N5V5-1", "protein_name": "Predicted gene 5862", "gene_name": "Gm5862", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLEENLIKKKLVILQQESKEVHADWATIHQSLVELNLSGKDEQEKTSNLETQEHQVSEAARELGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPEWE", "length": 267 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N660-1", "protein_name": "Predicted gene 10220", "gene_name": "Gm10220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRVNVDGRETREGRKDADLPSERNEGRRRWTWRMCMAHRQTTSPVPVKSKKQFEKEEKELIKKIQLTTEETNELRDRLIYVTEGSMNKRPYHRQTRHYKELKLKEKEIMTYLHDLEMKNMEARENNQELKKEKNFYRNLHTRILLGENLIKKKLAILQQESKEIHADWAIIQQRLVELNLSGKDEQEKTSNLEAQENQVSEAARKLGLATAEEDSILQNELPCQEAPAEHHPQHPPSSSDESSSDESSYSTCPSWE", "length": 267 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r168", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSQNGAMKTTEEVALQIVLLCQFGIGTMANILLFVHNFSPLLTGCQLRPKEVICANMAVSSILILFMTVFPNNVFVAQRNLLNDLQCKLEYFVYMVARSTNLCSTCVLSTYQFVTLVPGNFSELMVRGRSPKVISYSCCSCWLFGILYNVYIPMKVSGPQNRHNKTSTKSKWVCFTSGFSVGIVFLSFAHDAIFISIMVWASVSMVRLLYRHYQRLQYIFPPHQGNRGYAEIRAAHSIVLLVVTFVSFYLLHCICFILHIVFVDSNLWLRHIGEVLTSSFPTISPLLLIFRDPSYPCSLIFNYKKPVI", "length": 309 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6B7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Gm10670", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVRGKSLKTTEEVALQIILLCQFGVGTMANDFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTVFPNNMMAFAPRNPPTELKCKLKFFSHLVTRSTNLCSTCVLSMHQFVTLVPISRGKLLLRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSKFFCSTSGFTVRIVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATNTILMLVVTFVSFYLLNFICIIFHTFFIHYNLFIRLLGEILAAGFPTISPLLLIFRDPKNPCLELFHCFKPESLQNLKHRRQLH", "length": 321 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6G6-1", "protein_name": "Predicted gene 16440", "gene_name": "Gm16440", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLCQKENGDEGEIRTTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKITKQRSKINELEELKLDMRKISNDMEEMGGILELYIYEDLNYRMNTEFNIIKSQHEKTMLDMNEMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLSEKVRILLNENRKLLVEQAGTQLSHEEEKRFCEEASKNICASSAKEQQCVNSSRNRNMAQTTT", "length": 218 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6J5-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r127", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLTAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6P1-1", "protein_name": "Reproductive homeobox 2H", "gene_name": "Rhox2h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRSINYLLDVGPEEDEENANGVKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGPAAPVAGLMDNSNQEDLSATGCAQEKETQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPKFRHLWRHNFNVLQLQELESIFQCNHYISTTEENRLARSMGVSEATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r175", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGFGTAVNIFLIVHNLSPILNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCFLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVNGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSTNQKLRVHAETRASHTILLLVVTFVTCYLLDCICTVCNISFLDSRVWLRRVKQILDVSFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U2-1", "protein_name": "Predicted gene 3542", "gene_name": "Gm3542", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCQKENGDEGETRPKKKEEGILSHEKGRRKSFWRRHRSARNTSTQNSNITNQISNINKVEELKLHIRKTSNERKEMCGILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRKLLVEQAGTQVSCEEERGSLRRPARTSVPQVQRNSSFPKCETVQQKLEHGTDHDMISLKEKCWWKRTGCAQEIHHCCLSSLITMAVMGCMLLLYFGFLGMNRP", "length": 270 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W5-1", "protein_name": "Predicted gene 17019", "gene_name": "Gm17019", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFARLCRLFQRANVDGRDTREGRKDADLPSERNEGRRRWTWRMWMALRQTSSPVPVISKKQFEKEEKKLIKEIQLTTEETNELRDRLIYVTEGSMNKRPYHRQNPLYEKLKLKEKEIMTFLHNLEMENMEAQENKQELKKETHFYRNLHSRLLMEENLIKKKSMTLQQESKEVQADWAIIHQRLVELNLSVKDEQENSNLETPEYQVSEAARELGLATAEEDSILQNELPGQEAPAEHHLQHPQSSSDESSSI", "length": 255 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6W9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLQNKSVKTTEEVALQVLLLCQVGVGTAVNIFLIVHNLSPNLNGSQQRPIKVILANLAVGNTLILLFAFPNNMTLFVPKDPPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLRGRAPKFVRYICYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKNKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHHRLQHIQSTNQKLRVHAESRASHTILMLVVTFVTCYHLDCICTFCNISFLDSQLWLRRVKQILDASFPTFSPLLLIFRDPKDPCSLLFCC", "length": 304 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r94", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVIFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6X7-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r103", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Y3-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFSPVLTGSKQRPRQVILSHMAMANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPKFVSYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSIILLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFYIHSRLFIRLVSEVLAAVFPSICLHNGVLLSY", "length": 295 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z0-1", "protein_name": "Predicted gene 17026", "gene_name": "Gm17026", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "XRSSWVPKQACCPCSSGYFRERIEYTQTPDQGRRRPAAHHGGKGQETTGHGEGSAGAASPQAPTINDQEKRHERLEKLKRELQNIKNARDELQGILANYTNKDLNDRINFETFMLQMQHDQVMTDLKRMPQDISEALYKCKQLTKENQFYCFRNCHLLIESNLIQHKVRMLRKENRQLLREQIALEECNIETKILCKEGSQKIKDHYTKQQQI", "length": 213 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N701-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r159", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQLLLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMSVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVLVNRGKLILRASVPNLVSYSCYGCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVFLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNTRGQAESKATRTILMLVFTFVSFYLLNFICIIFHTLLMHSHFFIRLVSEVLAAVFPSISPFLLIFRDPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N708-1", "protein_name": "Predicted gene 10128", "gene_name": "Gm10340", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLHENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNTSVI", "length": 205 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N731-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r57", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALNILLLCHVVVGTVGNILLFVHNFSPNLTDSRLRPIQVILINLAVANAFMLLFSTYSYDLIDFVPRKPPTDLKCKLAYFFHMVARGTIMCSTCVLSTYQFVTLVPGNWARVMFREISPKVVSYSCFSCWLFSVLNNAYIPMNVSGPQKSHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFLGIMAWTSVSMVIHLNRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCIIILFHITFVESRLSLRHVTKLLSLSFPTISPLLLIFREPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N744-1", "protein_name": "Predicted gene 8104", "gene_name": "Gm8104", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLRRLFHRENGNQGETRPRQKESAIPSCKNRRMKSFWGRHMSAGKTSSQNCNITNHMKNMNKLDDMKFYIRKINAERLELFRILDIDMNTDLNYRMNIDFTIIKSQHEKTMLDMEKMTQSISDTIEKYKEFIEDKDSYSFTHTYLLKECNQLKEKVRMLLNENRKLLVEQADQETSYGEEKRFCDETSKNIHPKC", "length": 198 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N751-1", "protein_name": "Predicted gene 3696", "gene_name": "Gm3696", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPKKKEEGILSHEKGRRKWLWRRHRSARNTSTQNSKMTKKRSKRNELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPQEHLCPKCQGTAV", "length": 203 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N757-1", "protein_name": "Predicted gene 3667", "gene_name": "Gm3667", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKGRRKSFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNEKVRILLNENRRLLVEQAGHKCPVGKKRGSLRKPARTSVSQVPRNSSVK", "length": 205 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7F4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGNSLKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPTELKCKLESFSHLVVRSTNLCSTCVLSVHQFVTLVPLNRGKGKLVLRASVTNMASYSSCSCWFFSVLSNIHIPIKFSGPQITDNNTDSKRKLFCSTSGFSVGIVFLQFAYDATFMSIMVWTSVSMVLLLRRHRQRMQHILTPNQNPRGQAESKATHTILMLVFTFVSFYLLNCICIIVHALFMHSHFFVRLVSEILTAIFPSISPLLLIFRDPKDPCSVLFNC", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r163", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVMTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLKFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPNICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7G4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r242", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSIHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9J7H2-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r256", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILGHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSLLVARSTNLCSTCVLSIHQFFTLFPVSRGKGKLILRASVQNLASYSFYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDDTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAESRATHTILMLVFTFVSFYLLNCICIIFHAFSIHSCLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 306 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K9JA28-1", "protein_name": "Interferon lambda receptor 1", "gene_name": "IFNLR1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAWRIRVLATLCFLWQPRVHGQLPPPQNVTLLSKDFDMILTWTPGEGSPPDVLYTVRYESKTRMDKWIKVPHCRNIHSVSCNLTCVIPNFFIKFRAQVKATSGRFHSPWVKSQFKEYHLDVELAPPLLNVNVKENVIHVNATFPMAICVESLPWMYDFNLWEAGSEDKKQYKSIFRKKAVTIDTTALRGNYCFNARSSIQSIDFKHSKFSQPVCMQLNYEGEWKFPFSATIPVFVLLILLTSASIIWLLKQDAKHKKMPQTLDLSNCKIAGPTFCCELRENEFLTDCLICTDKPMSQGKKNKTLAQNNQMWMASFLPSSSSEEEEEEEEEDSSSFIPYTEMLQFPRKHFNFQTPRTADAETILDSTSGVLSVVGGSTLDLSALGFSFFPIRKNEMDTSGSQGNEKASHSHSSSLGRISLTDVRFPGPREHGQHGTDSNDCLEVSLLHTLMNSSCTRLPADEHCLYKKDHDFTICYQKPTLDQPVQVSENPLLNEDPSMEKFIYLQTLQVAEDEGFASDCDSGNFTEGTPPASTVLSDELRISDMEKRYDKKFKFKGYQHSHYMRRS", "length": 567 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "L7MU37-1", "protein_name": "Reproductive homeobox 3H", "gene_name": "Rhox3h", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMKPERSISNWIHSNVEPAGRNLFQVNGHRSALLPELPQDYHRASRSVNGCETKMDSTQGTKVLPAEESRNEEDGGQVESALGATAARGRGKEALNGESPAAAGTAGLVEEDRNKEDGGTKGGEKNEQEVREQIPEHVEGESDQAEAPRQVPRRRLHHRFTQWQLDELERIFRMNYFLSLEARKQLARWMGVNEAIVKRWFQKRREQYRWYKRL", "length": 215 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU51-1", "protein_name": "Olfactory receptor", "gene_name": "Or4a76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQSNNVTEFVLLGFTQDPAGQKALSVMFSLIYIVTMVGNLLIVGTVIASPSLGSPMYFFLASLSLMDAIYSTAITPKLIVDLLCEKKTISFRACISQLFIDHLFGGVDIVILLAMAYDRYVAICKPLHYLIIMNRRVCILFLVMAWAGGLAHALFQVLAVYNFPFCGPNIIDHFGCDIYPLLLLACTDTYFLGLSIIGNNGAMCIVIFTLLLLSYGIILRFLKNHSQEGRRKALSTCGSHITVVFLFFVPCIFMYVRPVSSFPIDKFITVIYTIVTPMLNPLIYTLRNSEMKNSMEKLLQKTLSPSRIRLSSCCLCY", "length": 318 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU81-1", "protein_name": "BTB domain containing 35, family member 17", "gene_name": "Btbd35f17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANTWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MU83-1", "protein_name": "BTB domain containing 35, family member 18", "gene_name": "Btbd35f18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGKTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDQVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7MUB9-1", "protein_name": "Reproductive homeobox 2G", "gene_name": "Rhox2g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERQSINYKLDVGPEEDEENANGIKTLMVLLAGEGRNEGESGRGLPGSGVSAAEGYRAGELSAGGLAAPVADLMDNNNQEDLGATGCAQEKEKQPEEPVPDSMGDLENVKPMSGPWSTVNPVRVLVPEFLHGWQQSFNVLQLQELESIFQCNHYISTTEAKCLARSMGVSKATVQEWFLKRREKYRSYKRL", "length": 191 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X6-1", "protein_name": "F-box/WD repeat-containing protein 15", "gene_name": "Fbxw15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAIHLPCLPMMKILSYLDAYSLLQAAQVNKDWNELASSDVLWRKLCQKRWLYCDMDTLQLQGKETWKQFFIDRIWQERAKFRAKAKDFTYKEIPLMCGLFGYACYISGCGLTRKGQDKSVVCMVNSKNTISTWDVHKSVITWKSPEQPASIKLLTTLPEMHIAVTVDIQSTIKLWDCHNREALATNNLKSPCKSLKAVFTKDGPIVLIGDTLGNIHIFRIPDLYLISTVNVLPYGFDGIYCSPQKKWVLLSKKHPHILPKVFYMSSFLRTSEFSAPVSTVLKLSLYERVFWTPRREDRITLMSRSGFPQVKMFETYDIKLEEFGNKRIVKGKLIASFELQCHKVNPQRFGVSDKNVIVCSTESSLLLFDINGLRLKTFQYCPEMIVKLSVDPLHVIVICNTGSMDVYAWEERSLLLRKCYRLHIERPLPLYGFIYKAACDDVSIIQLITDELSLSSLTSYALNICS", "length": 466 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X9-1", "protein_name": "Demilune cell and parotid protein 1", "gene_name": "Dcpp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSAPEGKNITSIRVFLKGRLIVGIQLNYDDNKDGQVYGSTAGKEMVARLSKEEHIIAAQGTYTPSALTQIIFTTNQPRQLMVGYYVGNSEYSSFPNDPSHVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 171 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y3-1", "protein_name": "PRAME like 51", "gene_name": "Pramel51", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIHSKERKYRLGLLEPGVTAFPCPNMVICLHCPDQDDSLEEVTEECYSPPTLQNLAIQSLLRDEALAISALTDLPQSLFPVIFEEAFTDGHIGILKAMIPVWPFPYLSLGKQINNCNLETLKAMLEGLDILLAQKVQTSRCKLRVINWREDDLKIWAGSHEGEGLPDFRTEKQPIENSPGCEVKKELKVTTEVLRMKGRLDESTTYLLQWAQQRKDSIHLFCRKLLIEGLTKASVIEIFKTVHADCIQELILRCICIEELAFLNPYLKLMKSLFTLTLDHIIGTFTLGDSEKLDEETIFSLISQLPTLHCLQKLYINDVPFIKGNLKEYLRCLKKPLETLCISNCDLSQSDLDCLPFCLNICELKHLHISDIYLCDLLLEPLGFLLERVGDTLKTLELVSCCIVDFQFSALLPALSQCSHLREVTFYDNDVSLPFLKQLLHHTALLSQLIYECYPAPIECYDDSGVILTHRLESFCPELLDILRAKRQLHSVSFQTTKCSKCGGCYIYDRHTQCCRFVEL", "length": 520 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1Y5-1", "protein_name": "Olfactory receptor", "gene_name": "Or11g25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLSSPSNSSTITGFILLGFAYPREGQILLFVIFFIVYILILMGNASIICAVYCDQRLHTPMYLLLANFSFMEIGYVTSTVPNMLANFLSDTKVISFSGCFLQFYFFFSFGSTECFFLAVMAFDRYLAICRPLHYSSLMTGRLRNTLVTSCWVLGFLWFPVPIIIISQMSFCGSRIIDHFLCDPGPLLALACSRVPLIEVFWSIIMSMLLVIPFLFIMGTYILVLRAVFRLPSREGQKKAFSTCGSHLTVVSLFYCSVMIMYLSPTSEHEAGMQKLVTLFYSVGTPLLNPMIYSLRNKDMKNALQKILRT", "length": 311 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N227-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r125", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSMKTTEEVALQIILLCQFGIGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMSAFARKTPPTELKCKLEFFSHMVARSTNLCSTCVLSVHQFVTLVPVNRGKGKLILRASVPNFANYSCYSCWFFSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N255-1", "protein_name": "Predicted gene 3099", "gene_name": "Gm3099", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSRLLRLCLKGNGDEGETRPKKKEEGILSHEKGRRKLFWRRHRSARNTSTQNSNITNQISNINEVEELKLHIRKISNERKEMCEILNVYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMTQFIIGSMQYSMELIEDNYSYSIKEDHLLRECTQLNKKVRILLNENRKLLVEQAGTQVSCGEEKRFCEEASKNICASSAKEQQLP", "length": 205 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N259-1", "protein_name": "Demilune cell and parotid protein 3", "gene_name": "Dcpp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFQLEAMLALLILAFLGTPTVLTQDYHGPEVGKHSCTSTPEEKNITSIRVFLQARSIVGIQFNYDDKDGQVYGSTAGKEMVARLSKEEHITGVEGSYSPSALTQIVFTTTQPRQLMVGYHVGIYQYSSYPDDPSFVLKGACVSWRAGGIKSILFLWGSENSSCVKYGHSG", "length": 170 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N270-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSLKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILIHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIHQFVTLVPVNRGKGKLILRASIPNLWNYSCYNCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFAYDATFMIIMVWTSVSMVLLLHRHRQRMQHILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNFICIIFHAFSIHSHLFIRLVSVVLAAVFPSICPLLLIFRDPKDPCSVIFKC", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N273-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVHDKSVKTTEEVALQLLLLCQFGVGTVANVFLFVHNFSPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMMAFAPKTPPNELKCKLESFSRLVARSTNLCSTCVLSVHQFVTLFPVSRGKGKLILRASVQNLASYSCYSCWFFSVLSNIHIPIRVTGPQITDNNTDSKSNLFCSTSGFIVGIVLQFAHDATFMSIMIWTSVSMILLLHRHCQRMQDILTPNQNPRGQAETRATRTILMLVVTFVSFYLLNCICIIFHAFFIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSLLFKC", "length": 306 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N275-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r169", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKSVKTTVEVALQILLLCQVGVGTVVNIFLFVHNLSPFLNGSQQRPIKVILANLALGNTLILLFAFPNNIRVFIPREFPTDLKCKLGYFIWLVARSTNMCSTCSLSTYQLVTLAPGTWGRVMLHGRAPKFVRYTCYSCWLFSVLNNAHIPMKVSGPQKTHNDTNTKSKWVCSTTGFSIGMRILSFAHDAVFISIIIWSSVSMVILLNRHHQRLQHIQSPNQKLRFHAETRAAHTILMLVVTFVTCYLLDCICTSLHISFVDSRVWLRRVKEILAVSFPTFSPLLLIFRDPKDPCSLPFSC", "length": 304 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N288-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r151", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDHGKSVKTTEEVALQILLLCQFGVGTLANVFLFVHNFYPVLTGSKQRPRQVILSHMAVANALTLFLTIFPNNMIAFAPKTPPTELKCKLEFFSHMVARSTNLCSTCVLSIYQFVTLVLVNRGKLILRASVPNFVSYSCYSCWFFSVLSNIHISIKVTGPQITDNNTDSKSNLFCSTSGFIVGIVSLQFAYDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQYRRGQAETRATRTILMLVVTFVSFYLLNFICIIFHTLLMHSHLFIRLVSEVLAAVFPSISPLLLIFRGPKDPCSVLFNC", "length": 305 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFFHNFSPVLTGSKQRPRQVFLSHMAVANALTLFLTIFPNNMSAFAPKTPPNELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLAAVFPSICPLLLIFRDPKDPCSVLFKC", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B4-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r128", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHGKSVKTTEEVALQILLLCQFGVGTVANVFLFVHNFSPVLTGSKKRPRQVILSHMAVANALTLFLTIFPNNMSAFAPKTPPTELKCKLEFFSHMVARSKNLCSTCVLSIHQFVTLVPVNRGKGKLILRASVPNLWNYSCYSCWFYSVLSNIHIPIKVTGPQITDNNTDSKSNLFCSTSGFIVGMVFLQFSHDATFMTIMVWTSVSMVLLLHRHHQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNCICIIFHAFSIHSRLFIRLVSEVLGAVFPNICPLLLIFRDPKDPFSVLFKC", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2C2-1", "protein_name": "Predicted gene 2974", "gene_name": "Gm2974", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSWLLRLFQKENGDEGETRPTEKEEGILSHEKERRKWFWRRHRSARNTSTQNSKMTKKRSKINELEELKLDMRKISNDMEEMCGILNLYMYEDLNYRMNTEFNIIKSQHEKTMLDMNKMIQSIIGSMQYSKELIEDNYSYSIKEDHLLRECTQLNENVRILLNENRRLLVEQAGHKCPVGKKRGSLRRPARTSVSQVPRNSSVI", "length": 205 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N474-1", "protein_name": "Spermatogenesis associated glutamate (E)-rich protein 1E", "gene_name": "Speer1e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "ARRHTSSTAPDLSKKEFKKEKERLTTELHLLIQLRNEQRDHLIDFKESSNYNRTKPTQKKNPFYEQLRSTKNQVLSSVHKLEMGIIEAQENIQELNKWIDYFTNLHSQLLMEKNLKMSITQNQKNKEVEIDWALIEKYLVDVNLNGRTGADQQP", "length": 154 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0QWR4-1", "protein_name": "Aly/REF export factor family member 14", "gene_name": "Alyreffm17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKMDMSLEDIIKLTKIQQRRHDRPDSRVNRGTGSKRYRPAFTHGGRNRLAPYCRPKQLPDKWQHDLFIGGFRGQNHVDTGGKLFLSNLHFGVSDADIQLLFAEFGTLKKSAVHYDRCGRSLGTAQVHFERKADALKAMREYNGAPLDGRPMNIQLATSQIDRQGRPAQSKNRGGMTRNPGSGVLSGGGTKKWTLGGSQGRGRGTIRNSKLQQQQQQQKQKQQQQQQKQQQKQQQKQQQQLSAEELDAQLDAYQEMMDTS", "length": 261 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R3T3-1", "protein_name": "Peptidase S1 domain-containing protein", "gene_name": "ENSRNOG00000067174", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRFLVLCLILSLGDYGAFPLIQSRIHRGCKGERHSQPWQVAMYHYDKAVGWGWHPSPTTMSTSPSHNKVRLGQHSLDADGDTGQDVPVRHSIPHPLYNRSLQMPTFLSPDADNSHNLMLRQLREPANTTEAVRVTEEPTEEAKLGSRCLASGWGSTRPDKCMPGMLQCVDLTLMSSDVCTYAYSQRVTESMLCAGHQEGSRDTCMGDSGTTLICDRMLQGITSWGGNPCA", "length": 230 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R777-1", "protein_name": "non-specific serine/threonine protein kinase", "gene_name": "Smokwl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKSKEKTLGSHYKILSYLGQGSFGTVNLAWHLKTQALVAIKMLEISKETISSILSERAILETLHHPNIIRLFQVLITSSHVNFVLEYAPGGSLFELIKEGGPLQEEVAKKIFGQTVSAVKYCHNLDIVHRDIKPQNILTDAEGNGKLTDFGLATKFRPGTLLKELCGTKEFYAPELVLREPYNGKKTDVWSLGVLLYFISTGYCPFRGVTTKDMEKKIATGTYTIPTYFSGQLENLIHQILTVSPEMRPSIEDIEKHPWVRKCEVNIPTITCPDYKIVEMLCGMGYNANKILESLQKKKYDEPMAAYLILKDKVRQEIEHGTTTSDMPVDQGPLPPQSPAHHSVSGLPLKRRASEPNFGLLHIWPPGEQVARHNVARSVSMPPIALYGTKKQNSTSTSALHSRPVASPCVCNTILEIEIPLPTKQDFDMKTSSPPQRIGYFQRLCQRIRDCLSRLCCFLWAPKVHSPRKWLP", "length": 474 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9M1-1", "protein_name": "Olfactory receptor family 52 subfamily N member 1B", "gene_name": "Or52n1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLLNVSSLTPASLILNGIPGLEEVNLCIFFPLFTMYSIALTGNFGLIYLIYSEEVLHRPMYIFLALLSFTDVLMCTSTIPNTLFISWFNFKKIDFKACLAQMFFVHTFTGMESGVLVLMVLDLYIAMCYPLRYATILTNVVIAKAGMLTFLRGVALVIPFIFLTKRFPYCKGNVIPHTYCDHISVAKISCGNVQINAIYGLMVVLLIGDFDIPCITVSYTMILWAAVSLSSADARQKAFSTCTAHICAIVITYVPAFFTFFTHRFGWHTIPSHIHIIMANLYLLMPPTMNPIVYGVKTKQIQKRVIRFFFKGRENSSHKF", "length": 321 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R9X6-1", "protein_name": "Paired immunoglobin-like type 2 receptor beta 1 like 2", "gene_name": "Pilrb2l4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAWILLLLLLAACLHTGNSAGYQKTQDYGVNQPEQLTGIQGGSIEIPFSFYFPWELAKDPQMSIAWRWKVFFGEVIYNSTLLFLHEHFKGRLIMNWTQGQTSGVLRILNLKANDQSTYFSRIFLQATEGMKLWQSRAGTKLIIHALSTTMASPSIIPSAVPTAGLENTRGQRNPSLLNLGAMVGMVMAKVVVIIPLYGWVIFLWWKQRLPTARISHQVSLHHTPCIPQSSMSSLWESELVAAGFSCESHSWITPTSAMGARIPSPWNQGPPVCLWA", "length": 289 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RAD6-1", "protein_name": "Olfactory receptor", "gene_name": "Or1f19f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSTNQSSVSEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILVISTDSHLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILSSQAISFSGCLTQLYFLCVSVNMDNFLLAVMAYDRFVAICHPLYYTTKMTHQLCVLMVSGSWVTASLNALLHTLLMARLSFCGDNIIHHFFCDVTPLLKLSCTATNLNELMILTEGAVIMVTPFVCILISYIYITNAVLRVSSFRGGWKAFSTCGSHLAVVCLFYGTIIAVYFNPVSSHSSEKDTAATVLYTVVTPMLNPFIYSLRNNDLKGALRKVVHRKI", "length": 309 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RBH5-1", "protein_name": "Surfactant associated 2", "gene_name": "Sfta2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSMCLFLLLTLLCSSLAGPTKVTLQVKLTEASQAKTSQDSGFLDMLQKICLLLHLSPGTNVTLHHKGPPHHLTCRA", "length": 78 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCJ6-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "AABR07013776.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADQLTEEQIAEFKEAFPLFDRDGDQTVTTKELGMVMGSLGQNPTEAELQDMISEVDADGNGTINFPEFLTMMARKMKGTDVEEEIREAFRVFDKDGYTSAAEFRHVMTTLGEKLTDEEVDGMIREADMDGDGQVIYEEFVQMVTAK", "length": 147 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCP1-1", "protein_name": "Leukocyte immunoglobulin like receptor B3", "gene_name": "Lilrb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVSTLTALAYLGLILGSENPVLSGAFTKPTIKMVPSNVVTTGKQVTIFCEGSSHAKEYRLHKEGSPDYLTPTTFLETENKAKFSISPIQWNNAGQYWCSYRSLTNKLRQSDIMELVVTGVILGEVTLSALPSYVVTSGRNVTLQCASQVVYDRFILMKEDEKFSTAMPSWKIYPVLWGAIFTLGPVTSNQRWRFTCYGYYLSSSLIWSKPSNHLELLVSGTLHKPILWAHPGSMVTSGSPVTIWCEGDQETQTYVLYRQGSLESWNRQTQKDYNNKAEFTIPSVTYLNAGHYFCYSYTSAGWSEHSDTLELVVTGVYKKPIFLALKNPIVNLGVTVTISCTSNQSFNCFLLMDDDQKIYRFFDLQYSYSGESLARFQVGPITSRQRWRFRCYGYYTDNPQVWSEASDPLDFLVSGNLQKPTLWAEPGSVIESGNSVTIWCEGTMETQIYFLYKEGSPSSWLRQTPKEPGNKAMFFIAFMEKHNAGQYRCYCYNFGGWSQHSDTLELVMTGVHHGKPTLSAFPSPMVTSGGNVTLYCASSTIYDWYIVTGQDLKFSRFQRAQFIPTEMSQALFSEISVASRKKGPFRCYGFNESTPHLWSEASNPLEIHVSGVSRKPSLLNQQGPVLAPGENLTLRCSSELSYDRFSLSKEGRSDLPQLSVSQSQTGEYYANFFLYSVDFSIAGQYRCYGASRFSSEWSAPSVPQDILVTGHPPITPSLSVNPGTIVSSGENVTLLCQSSIPMDTFFLFKKGDAYPYMHQRLKFQGPQCKAEFSLSAVTPNIGGIFTCFGSQSSSPYLLSHPSVPVEIKVSGLAKYQKSLIWVSVVFFLLFFVLTLFFFLRLWHQNKHRKGVQTKIDLQHPEGAVEPKSIVGHLQKSSRPAPAIQEEILCEKRWPGREITEVSASDATVKVTRSADNVELGILSQHQDDPSIHLYAQVKPARLRRAQTTSSSLFPKELQHSKHRQKNRDQVIDQQADTSQDSHAVIYAQLHIMTPRQGRQTSLFPGRIC", "length": 1008 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCQ2-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "LOC100361204", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQSSIP", "length": 328 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCW7-1", "protein_name": "Uncharacterized protein", "gene_name": "Pilrb1l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLVSLPEQNLAMAQLLLLLLSAACLHTGNSAGYPKKNVFSVDQPAVLSGVQGGSIEISFSFYFPWELAKVPQMSIAWRWKNYHGEYIYNSTQPFIHEHFKGRLIVNWSQGQTSGVLRILNLKENDKATYFSRVFLPTTEGMKSWQSVAGTQLIIIHAPSTTVVSPSIIPSVVPIAGLEDTRGKRTPSLLNLGAMVRMVVSKVVVIIALYGWVIFLWWKQRSAWSLLSFLTTWKSEEQMQMNTAPAPKEFK", "length": 252 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RCY4-1", "protein_name": "Retinoic acid early-inducible protein 1 domain-containing protein", "gene_name": "AABR07000137.1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSAPLGSLGRKSKNQSLGLDMLGTVLSTDSLSCTFTVKYRSSPGQCSVNGKPLLLFNDERQNSPVGKPEKKGNATKVCAELNQSLKDIFQKMMNLESWLFESKGNHTLQVTVQSQYNQGIFMDGCWVFTIDRQYPFYFYPKIMTWRESHPDASRTVSQWQNNRQVAQSLRTCSMGDFSQCLRKLLTDSREVPRSTITTLDPTQPSSAIQIPPTVDSASSVFTTWSQYIFVLILCLAILIINALIP", "length": 246 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RD07-1", "protein_name": "Uncharacterized protein", "gene_name": "ENSRNOG00000064269", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMMAMQMMTNSISDAMERYKELIQVNSSYNIRQSQLLREQAQLKNNIQILLNEKRELLVEETELPASSVEAKRLCEEAGMNICDPRAKQQQV", "length": 93 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RDP5-1", "protein_name": "Zinc finger protein 353", "gene_name": "Zfp353", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVAETPGASQTVPCNTQPSPVESSQLVSGQSSEMPTWKKTVMASACCNPQETACTQNSTAHPGKASDFYFGEPSETASFIQQVVSAEQKSSPAGSCLMNLSSTTKSCLSHPLKTEVLDTRKTLCNEGHWGRTLNSDKTLLIQITTMYESQWRTLGNHPVAPSGYHEGQAPNMDHLVDSVSNQTFIGDLEMEPSCNHVLYTDQFITSFSEQNPFGDQQRSPVADNRFYADQKILPNGYQTFYEPQMSTNYQITCVCGQNVCRCQEILLSGEHLLSEYQTSGYRYDQDLIVNLQVTSPIGGEPLHDSQIPNSNFDTTSCGTKRTTSSEEDNLAWHPETSLSSEETFLDQMRTSVDQNVYPSHNGTLKIEESLEPQVTSLSNQAPYVGESSDTSNSPLIQIQPQEISSASGLDQGQHPEIKLDLKTQSPVSLKNPHNSKRYCCTYQGCKKSYKKSQHLKDHMKKHTGVKPYMCNKPGCDWKFFRLVDLNRHKQKHSGERPYPCPMCNKNYSRFYYLKQHLRSHIQASPTTAT", "length": 530 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9MSI7-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG42818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFIHQREQLPFKHNEQDPNYLAPVIQKRKPMDKDPRNPLKRLKFLQEFPTQSSKGDLDDLKYPTQLEGRHDSPKYDKTFHTEIHANNETDSQELENIILEKNLQDSKTEFQENRASQPKNMHSFQIPEAIESHFNNKELQNENDLHKGLKQQYRSGSEQDKSGPENVREIASKLILQWAENQRSLLDSFVKAITDVLKVHDSKLNMKINISPRDIMILKDMLKQLLESIMQLREGSTSTRARIVLNKWIETQKSLIDSFSQAIQNTNQNVDNIANVYEVMENLNKNLRELVILLSDKESFPTTESSSSQQTTSIYATTTFYLTSSTFGSTHPIVDENINRVNIMGNLIKGLRNIMVQMDETNKTSSSTSYTTTESTYIQPSTSTYLNAEVTTSHPTTSTYEVTNIITDESKIKDMFNLIKGIEDLISQYNGKHKFTSTTSLTGKSNSREPTMTTYSSAGGITSHSFTTTSPKTVTTSSSHSTTESSPSHPTTSNYEVTVFDQDSHKFKVMKNLIKELKGLIEHFSDTKNITSTTYSTGDSKSFQPTATTPDSTDRSSSQPITFPESTTSTTNLQSTITNHLSTESTSSQLNTTLSITGTTTPNLTTSTHDFKDQINDDDSKSLKHLIKILSDLVYSLNDKNNIKSTSQLTTESTFNSSINITNSTTVASSTFSTTESMAIHSTPYLSTREITVFQFNDVENINPIISNNSTTVTTNIHSSTYTTSTTDNTTSYPNLSTTESSPTFDSTISHSNTSSQTRSLGSYKDKIKNIVELLKKLRKIQKTLADKSKGQLSPMLISRIKAVLKQIVAGNIDSVNGDSTELEILLSTTVNPNEDTTDLTMEKLLKLFDDFERMYNVLLDDSIQSTTQSTTQNNTIFSTTYSTIFSTTQSISTTSPTQYALTSSTPNTSTTSHSSTPSSINNLRSDESNNHQPIVDAIQQLKMALYHDFYAFKKSQEERMEKILQLLNGKPIDRRTKTIAKPRTIRKKVSREIQKRNSDVKEDKIHHYKADKFIKNPKNGNQDSHIPKPILNSARSKIKDVPLKLSAIKVNGGLKHLPSKRKANEEVSAMHEIFPEPVSILPHK", "length": 1085 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O08640-1", "protein_name": "Keratin-associated protein 14", "gene_name": "Krtap14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCNSCSGTFSQSFGGQLQYPISSCGSSYPNNVFYSTDLQTPITHQLGSSLHSGCQETFCEPTNCQTAYVVSRPCQRPFYSQRIRGPCRPCQSTFSGSLGFGSRGFQSFGCGYPSQGFGSHGFQSVGCGTPTFSSLNCGSSFYRPTCFSTKSCQSVSYQPTCGTGFF", "length": 167 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O21032-1", "protein_name": "Large ribosomal subunit protein uL16m", "gene_name": "mrpl16", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIPNRQKFTKNHKRNLITKETRKTGLVLGNYGIKATETGYLKMKQMERIKGDLVKKLKDNMDIYFNFYPLFGLTNKGTARMGAGKGEVSEWYVLVKKGSIVVEFIKSRMTAGAMQKVIRYSANKWPIKVRMTQIKQGLYEKKI", "length": 144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21042-1", "protein_name": "Cytochrome c oxidase subunit 1+2", "gene_name": "2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKILEIYDKQIAEKEGNIFIFISKWIISVDHKNIGTMYTNFSILAGIVGTLLSLVIRMELSTGNMLDGDGQQYNVIVTAHGLIMIFFVVMPAMLGGFANWFIPIMVGSPDVAFPRLNNISLWLIIVSFFLLLTSSCVGIGVGTGWTVYPPLSTMEYHPGHAVDVGILSLHIAGASSLLGAINFLTTVFNMKIAGLSWSKVSLFVWSILITAVLLVLSLPVLAGGLTMLITDRNFETTFFDPIGGGDPILYQHLFWFFGHPEVYILILPGFGLVSIILSKYSNKGIFGVKGMISAMSAIGFLGFLVWAHHMYTVGLDVDTRAYFTAATMIIAIPTGIKIFSWLATLWGGVIKITTPMLFVIGFLVLFTIGGLTGVVLANGGLDISLHDTYYVVAHFHYVLSMGAIFAIFAGYYYYYSIMNSTRLFGVVRYNEQLGRIHFWTMFIGVNVTFFPMHFLGLAGMPRRIGDYPDAYIGWNLIASYGSLITAFGLLFFVVNIFTPYIRRSVNIKNGAIILMGLDFARDWQIGFQDPATPIMEGIIDLHNYIFFYLIVVAVFIGWVMGRILWRFSYKWSYPTIGDIEIFKNFTAYNQIIHGTVIEIVWTLIPTVILYLIAIPSFTLLYAMDEIINPTVTIKIIGHQWYWSYEYGDNASNLIEFDSYMVYERDLAEGQLRLLEVDNAMVVPVKTHIRLIITSGDVLHSWAIPSFGIKVDAVPGRLNQIGLYVKREGTFYGQCSELCGVDHGFMPIKVQAVKLGEYFSKLNEK", "length": 764 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O21049-1", "protein_name": "Cytochrome c oxidase subunit 3", "gene_name": "cox3", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKGFFENLFRQNVRSVINTGKKVGARAAAREIINQEWGYPLANHEVLFLTNVYQPKHMKRHPFHIVRGTVAPLAVTLPLGFFVLNYFGVISSKLGLLIALSSFIGGLVIWTISIIFDSLYDQQHTYEVKRGLVMGMMMFIISEVMFFFSFFWSYFYISLSPNIAIGCVWPPYGLTVYSYMGLPLLNTVLLLLSGAILTDGYTILTEQKAVHEKNEKVLAVEEAFKNLMNLYKTKNSINTLTFVDERRDKFFGKESRQEDKIAEQKLIAISAGVKELRDLDWDLYFFENPENIEPNYKEPTNLSVIEYALITIYLKKRNKVIKTRLYFTLLCAVVFLACQGYEYFFAPFSMNDGIYGSLFFLLTGFHGFHVLVGSILIGIITIRFIVGNFNLLNVGTNFQIYKNKSTGFACTLFYWHFVDIVWIFLYIVIYWWGSR", "length": 435 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "O23373-1", "protein_name": "Formin-like protein 3", "gene_name": "FH3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MGRLRLAFLAISLVVFVCVSEEIFSRGGLNLLRFSVYGEDVAEQTWIHQNPRRKLISYPKKFSVSAPNLAFGPAPSFAPGPGPSFAPGPAPNPRSYDWLAPASSPNEPPAETPDESSPSPSEETPSVVAPSQSVPGPPRPPPQREKKDDILMKLIIAVASTAVLTFVFVALMFLCCFKRNCNNAVGSRDGPRDEGPLLRLSTGSTENSPTVASTSRKMFSVASSKKRSFLSRVSLKRNGHEFSTAESSSAAGLPPLKLPPGRSAPPPPPAAAPPPQPPPPPPPKPQPPPPPKIARPPPAPPKGAAPKRQGNTSSGDASDVDSETGAPKTKLKPFFWDKMANPDQKMVWHEISAGSFQFNEEAMESLFGYNDGNKNKNGQKSTDSSLRESPLQYIQIIDTRKAQNLSILLRALNVTTEEVVDAIKEGNELPVELLQTLLKMAPTSEEELKLRLYSGDLHLLGPAERFLKILVDIPFAFKRIESLLFMISLQEEVSGLKEALGTLEVACKKLRNSRLFLKLLEAVLKTGNRMNVGTFRGDAQAFKLDTLLKLSDVKGTDGKTTLLHFVVLEIIRSEGVRALRLQSRSFSSVKTDDSNADSSPQSVERYRSTGLQVVTGLTTELEDVKRAAIIDADGLAATLANISGSLTNAREFLKTMDEESDFERALAGFIERADADFKWLKEEEERIMVLVKSSADYFHGKSAKNEGLRLFAIVRDFLIMLEKVCREVKETTKTTNHSGKKESEMTTSDSNQPSPDFRQRLFPAIAERRMDSSDDSDDEEDSSPS", "length": 785 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O35698-1", "protein_name": "RNA-binding motif protein, Y chromosome", "gene_name": "Rbmy", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAETNQPGKIFIGGLNIKTRQKTLQEIFGRFGPVARVILMRDRETKKSRGFAFLTFRRLADAKNAVKEMNGVILDGKRIKVKQARRPSSLESGSKKRPPSFSRTRGASRILKCGRGGRSRARSGPSCEGNLGGDRYTPNFNVSSSGRHFAVKRNPSSKRDDPPSKRSATSAQTRSNTGLRGREPHRREISRNMPRGEPASSRRDEYPLPRDYGQSSNDRKYESTSRGYCDYGNYHSREESASKVFSDHAGYLGGRDRDFSEYLSGNSYRDTYRSYGRFHEAPSARGGNNRYDDYSNSQDGYGGRGEPYISNRSNIYSSDYERSGRQEVLPPPIDREYFDREGRQERGHSPKDGLYSASRESYSSNTKIWGIPWRSWRKQI", "length": 380 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O60309-1", "protein_name": "Leucine-rich repeat-containing protein 37A3", "gene_name": "LRRC37A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSAQCPALACVMSPLRFWGPWPLLMWQLLWLLVKEAQPLEWVKDPLQLTSNPLGPPEPWSSHSSHFPRESPHAPTLPADPWDFDHLGPSASSEMPAPPQESTENLVPFLDTWDSAGELPLEPEQFLASQQDLKDKLSPQERLPVSPKKLKKDPAQRWSLAEIIGIIHQLSTPQSQKQTLQNEYSSTDTPYPGSLPPELRVKSDEPPGPSEQVGPSQFHLEPETQNPETLEDIQSSSLQQEAPAQLPQLLEEEPSSMQQEAPALPPESSMESLTLPNHEVSVQPPGEDQAYYHLPNITVKPADVEVTITSEPTNETESSQAQQETPIQFPEEVEPSATQQEAPIEPPVPPMEHELSISEQQQPVQPSESSREVESSPTQQETPGQPPEHHEVTVSPPGHHQTHHLASPSVSVKPPDVQLTIAAEPSAEVGTSLVHQEATTRLSGSGNDVEPPAIQHGGPPLLPESSEEAGPLAVQQETSFQSPEPINNENPSPTQQEAAAEHPQTAEEGESSLTHQEAPAQTPEFPNVVVAQPPEHSHLTQATVQPLDLGFTITPESMTEVELSPTMKETPTQPPKKVVPQLRVYQGVTNPTPGQDQAQHPVSPSVTVQLLDLGLTITPEPTTEVGHSTPPKRTIVSPKHPEVTLPHPDQVQTQHSHLTRATVQPLDLGFTITPKSMTEVEPSTALMTTAPPPGHPEVTLPPSDKGQAQHSHLTQATVQPLDLELTITTKPTTEVKPSPTTEETSTQLPDLGLAIIPEPTTETGHSTALEKTTAPRPDRVQTLHRSLTEVTGPPTELEPAQDSLVQSESYTQNKALTAPEEHKASTSTNICELCTCGDEMLSCIDLNPEQRLRQVPVPEPNTHNGTFTILNFQGNYISYIDGNVWKAYSWTEKLILRENNLTELHKDSFEGLLSLQYLDLSCNKIQSIERHTFEPLPFLKFINLSCNVITELSFGTFQAWHGMQFLHKLILNHNPLTTVEDPYLFKLPALKYLDMGTTLVPLTTLKNILMMTVELEKLIVPSHMACCLCQFKNSIEAVCKTVKLHCNSACLTNTTHCPEEASVGNPEGAFMKVLQARKNYTSTELIIEPEEPSDSSGINLSGFGSEQLDTNDESDVTSTLSYILPYFSAVNLDVKSLLLPFIKLPTTGNSLAKIQTVGKNRQRLNRVLMGPRSIQKRHFKEVGRQSIRREQGAQASVENTAEEKRLGSPAPRELKQPHTQQGPEKLAGNAVYTKPSFTQEHKAAVSVLKPFSKGAPSTSSPAKALPQVRDRWKDLTHAISILESAKARVTNMKTSKPIVHSRKKYRFHKTRSRMTHRTPKVKKSPKVRKKSYLSRLMLSNRLPFSAAKSLINSPSQGAFSSLRDLSPQENPFLEVSAPSEHFIENNNTKDTTARNAFEENVFMENTNMPEGTISENTNYNHPPEADSAGTAFNLGPTVKQTETKWEYNNVGTDLSPEPKSFNYPLLSSPGDQFEIQLTQQLQSVIPNNNVRRLIAHVIRTLKMDCSGAHVQVTCAKLVSRTGHLMKLLSGQQEVKASKIEWDTDQWKTENYINESTEAQSEQKEKSLEFTKELPGYGYTKKLILALIVTGILTILIILLCLIEICCHRRSLQEDEEGFSRDSEAPTEEESEALP", "length": 1634 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O80489-1", "protein_name": "small monomeric GTPase", "gene_name": "SARA1A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MFLFDWFYGILASLGLCKKEAKILFLGLDNAGKTTLLHMLKDERLVQHQPTQHPTSEELSIGKINFKAFDLGGHQIARRVWKDCYAKVDAVVYLVDAYDRDRFVESKRELDALLSDEALANVPCLILGNKIDIPYASSEDELRYYLGLTNFTTGKGIVNLEDSGVRPLEVFMCSIVRKMGYGEGFKWLSQYIK", "length": 193 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O80614-1", "protein_name": "RING-type E3 ubiquitin transferase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSDMRDERFFYHRYLSVTNRTTPTTATNLPTSTSNMRSTSLMTPRVAHTSMSSGGDFPDDRFFHARHQSATDRAASNRSRAIMPISTTNVPSSTSNSPRVLQTSMSRRGTSPMSSSTRRSVQASMSARETVPSSTSTRSMQTSTSTPEIMPTSSRNVITSSEEVANTFTQTSYIQFGSLWETNTTPSTRSWPTVPSSNSPRVLQTSMSRRGTSPMSSSTRRNVQSSMSGRETVSSSTSTSSMQTSMSTPEIMPTSSRNVITRSEEVANTFSTQTPYIQFGRLWETNTTSSTRSRTTVPTSTTNVPSSNSSRVLQTSMSTRGTFPMSSSTRMSVQASMLAPGTVSSSMSTVEIMPTSARNMITMSEEVANSFTQTSYIQFGSLWETFKTVTKLSRVAMVENGECVICLEEWRKETYVTSSTSNMRTSSLMTLTRFIDEQISLRATVSSTRTTARLLTNESPATIRAVAMLPRVAMVEKGECVICFEEWSKSDMETELPCKHKYHLECVEKWLKIHTSCPQCRYKLSCVYKSFLML", "length": 535 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O81153-1", "protein_name": "Proteasome subunit beta type-3-B", "gene_name": "PBC2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSIFEYNGSAVVAMVGKNCFAIASDRRLGVQLQTIATDFQRISKIHDHLFIGLSGLATDVQTLYQRLVFRHKLYQLREERDMKPETFASLVSAILYEKRFGPFLCQPVIAGLGDDNKPFICTMDSIGAKELAKDFVVSGTASESLYGACEAMFKPDMEAEELFETISQALLSSVDRDCLSGWGGHVYVVTPKEVKERILKGRMD", "length": 204 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P00757-1", "protein_name": "Kallikrein 1-related peptidase-like b4", "gene_name": "Klk1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSQVDCENSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLGKNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVVKPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAMLCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRETMANNP", "length": 256 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01241-1", "protein_name": "Somatotropin", "gene_name": "GH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATGSRTSLLLAFGLLCLPWLQEGSAFPTIPLSRLFDNAMLRAHRLHQLAFDTYQEFEEAYIPKEQKYSFLQNPQTSLCFSESIPTPSNREETQQKSNLELLRISLLLIQSWLEPVQFLRSVFANSLVYGASDSNVYDLLKDLEEGIQTLMGRLEDGSPRTGQIFKQTYSKFDTNSHNDDALLKNYGLLYCFRKDMDKVETFLRIVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P02762-1", "protein_name": "Major urinary protein 6", "gene_name": "Mup6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04071-1", "protein_name": "Kallikrein 1-related peptidase b16", "gene_name": "Klk1b16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWFLILFLALSLGGIDAAPPVQSRIVGGFKCEKNSQPWQVAVYYHKEHICGGVLLDRNWVLTAAHCYVDECEVWLGKNQLFQEEPSAQNRLVSKSFPHPGFNMTLLTFEKLPPGADFSNDLMLLRLSKPADITDVVKPIDLPTKEPKLDSTCLVSGWGSITPTKWQKPDDLQCMFTKLLPNENCAKAYLLKVTDVMLCTIEMGEDKGPCVGDSGGPLICDGVLQGTVSIGPDPCGIPGVSAIYTNLVKFNSWIKDTMMKNA", "length": 261 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P04644-1", "protein_name": "Small ribosomal subunit protein eS17", "gene_name": "Rps17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKNLRNKIAGYVTHLMKRIQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVTQPTVGMNFKTPRGAV", "length": 135 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05817-1", "protein_name": "Prestalk D11 protein", "gene_name": "ampA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKLILLLILSSCLVLSVKSEVNVDCSLVRCAQPICKPHYRLNMTDSCCGRCEPCTDVACTLQVKYCQDGEVPTGCCPCTLPPTKPDCSLVKCARPVCKPYYRLNMTDSCCGRCEPCTGVACTLQIKYCKDGEVPTGCCPCTPQPTKKPDCSKVPCPKILKYCQEGELPTGCCPCTPQPTKKPDCSRVPCPKILKYCKEGELPTGCCPCTPQPTKKPDCSDVMCTMDIRYCKNGELPTGCCPCTPQETKVPDCSKAMCTMDIKYCKPGEKPFGCCPCRENLTQ", "length": 284 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P06325-1", "protein_name": "T-cell receptor gamma chain V region 5/10-13", "gene_name": "Tcrg-V1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLRWPTFCCLWVFGLGQLEQTELSVTRATDESAQISCIVSLPYFSNTAIHWYRQKAKKFEYLIYVSTNYNQRPLGGKNKKIEASKDFQTSTSTLKINYLKKEDEATYYCAVCRSGTSWVKIFAKGTKLVVIPP", "length": 135 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P06349-1", "protein_name": "Histone H1t", "gene_name": "H1-6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSETAPAASSTLVPAPVEKPATKRRGKKPGMATARKPRGFSVSKLIPEALSMSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGTGASGSFKLSKKAASGNDKGKGKKSASAKAKKLGLSRASRSPKSSKTKVVKKPKATPTKGSGSRRKTKGAKGLQQRKSPAKARATNSNSGKSKMVMQKTDLRKAAGRK", "length": 208 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07628-1", "protein_name": "Kallikrein 1-related peptidase b8", "gene_name": "Klk1b8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRFLILFLALSLGGIDAAPPLQSRVVGGFNCEKNSQPWQVAVYDNKEHICGGVLLERNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLTLKEIPPGADFSNDLMLLRLSKPADITDAVKPITLPTKESKLGSTCLASGWGSITPTKWQKPDDLQCVFLKLLPIKNCIENHNVKVTDVMLCAGEMSGGKNICKGDSGGPLICDSVLQGITSTGPIPCGKPGVPAMYTNLIKFNSWIKDTMTKNS", "length": 261 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P07647-1", "protein_name": "Submandibular glandular kallikrein-9", "gene_name": "Klk9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWFLILFLALSLGQIDAAPPGQSRVVGGYNCETNSQPWQVAVIGTTFCGGVLIDPSWVITAAHCYSKNYRVLLGRNNLVKDEPFAQRRLVSQSFQHPDYIPVFMRNHTRQRAYDHNNDLMLLHLSKPADITGGVKVIDLPTEEPKVGSICLASGWGMTNPSEMKLSHDLQCVNIHLLSNEKCIETYKNIETDVTLCAGEMDGGKDTCTGDSGGPLICDGVLQGLTSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKENP", "length": 259 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08932-1", "protein_name": "T-kininogen 2", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLITILLLCSRLLPSLAQEEGAQEMDCNDETVFQAVDTALKKYNAELESGNQFLLYRVTEGTKKDGAETLYSFKYQIKEGNCSVQSGLTWQDCDFKDAEEAATGECTTTLGKKENKFSVATQICNITPGKGPKKTEEDLCVGCFQPIPMDSSDLKPVLKHAVEHFNNNTKHTHLFALTEVKSAHSQVVAGMNYKIIYSIVQTNCSKEDFPFLREDCVPLPYGDHGECRGHTYVDIHNTIAGFSQSCDLYPGDDLFSLLPKKCFGCPKNIPVDSPELKEALGHSIAQLNAQHNHLFYFKIDTVKKATSQVVAGTKYVIEFIARETNCSKQTNTELTADCETKHLGQSLNCNANVYMRPWENKVVPTVRCQALDMMISRPPGFSPFRLVQVQETKEGTTRLLNSCEYKGRLSKAGAGPAPDHQAEASTVTP", "length": 430 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C0S7-1", "protein_name": "Histone H2A.Z", "gene_name": "H2az1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGGKAGKDSGKAKTKAVSRSQRAGLQFPVGRIHRHLKSRTTSHGRVGATAAVYSAAILEYLTAEVLELAGNASKDLKVKRITPRHLQLAIRGDEELDSLIKATIAGGGVIPHIHKSLIGKKGQQKTV", "length": 128 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C2B7-1", "protein_name": "Large ribosomal subunit protein mL52", "gene_name": "MRPL52", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALGMLLSTGVRRLHCGSAARAGSQWRLRQGLAANPSGYGPLTELPDWSYADGRPAPPMKGQLRRKAQREKFARRVVLLSQEMDAGLQAWQLRQQEKLQEEKRKQQNALKPKGVLLQNPGPSQ", "length": 124 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0C644-1", "protein_name": "Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1", "gene_name": "Ppip5k1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWSLTANEDEDESATAHFFLGAGDEGLGTCGIGMRTGESDSELLEDEEDEVPPEPQIIVGICAMTKKSKSKPMTQILERLCRFDYLTVVILGEDVILNEPVENWPPCHCLISFHSKGFPLDKAVAYSKLRNPFLINDLTMQYYIQDRREVYRILQEEGIDLPRYAVLNRDPACPEECNLIEGEDQVEVNGAVFPKPFVEKPVSAEDHNVYIYYPSSAGGGSQRLFRKIGSRSSVYSPESSVRKTGSYIYEEFMPTDGTDVKVYTVGPDYAHAEARKSPALDGKVERDSEGKEVRYPVMLTAMEKLVARKVCVAFKQTVCGFDLLRANGHSFVCDVNGFSFVKNSMKYYDDCAKILGNTIMRELAPQFQIPWSIPTEAEDIPIVPTTSGTMMELRCVIAIIRHGDRTPKQKMKMEVTHPRFFALFEKHGGYKTGKLKLKRPEQLQEVLDITRLLLAELEKEPGAEIEEKTGKLEQLKSVLEMYGHFSGINRKVQLTYYPHGVKASSEGQDLQREPPAPSLLLVLKWGGELTPDGRVQAEELGRAFRCMYPGGQGDYAGFPGCGLLRLHSTFRHDLKIYASDEGRVQMTAAAFAKGLLALEGELTPILVQMVKSANMNGLLDSDSDSLSSCQHRVKARLHHILQQDAPFGPEDYDQLAPTGSTSLLNSMSVIQNPVKVCDQVFALIENLTHQIRERMQDPSSVDLQLYHSETLELMLQRWSKLERDFRQKSGRYDISKIPDIYDCVKYDVQHNGSLGLQGTAELLRLSKALADVVIPQEYGISREEKVEIAVGFCLPLLRKILLDLQRTHEDESVNKLHPLYSRGVLSPGRHVRTRLYFTSESHVHSLLSVFRYGGLLDETKDAQWQRALAYLSAISELNYMTQIVIMLYEDNTRDPLSEERFHVELHFSPGVKGVEEGSAPAGCGFRPASSENEEMKTDPGSIENLCPAKPSDEPDRALQTSPQPVEGTGLPRRSPLIRNRKAGSMEVLSETSSSRPGGYRLFSSSRPPTEMKQSGLGSQCTGLFSTTVLGGSSSAPNLQDYARTHGKKLPPAGLKHRDELLFVPAVKRFSVSFAKHPTNGFEGCSMVPTIYPLETLHNALSLRQVSEFLTKVCQRHTDAHAQASAALFDSMHNHQASDNPFSPPRTLHSPPLQLRHRSEKPPWYSSGPSSTVSSAGPSSPTTVDGNSHFGFSDQSSVNTQMIEEKQGLGLLQETPGDGTPEFHIELAESTQSPQEPPVEISPPGSQDDTEVNQTCQEVPDTIQPCHDILEEIGQPNQEVPDISQLLLKNHDTATNTCQPCQASQLSKKVYEEICQLCQDNPEESNQLCQEVSVELGRMVHRFPVSIGSTTQETLMEIGRPTQEIPEEPCQEFSEKVGMLTQKASAISELSQDILETDNPSQELSEETDLQAQEVSEEIDQEPEVVDELSNEDIS", "length": 1434 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0C7H9-1", "protein_name": "Inactive ubiquitin carboxyl-terminal hydrolase 17-like protein 7", "gene_name": "USP17L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLGGDWQFNHFSKLTSSRLDAAFAEIQRTSLSEKSPLSSETRFDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQKIGNTFYVNVSLQCLTYTLPLSNYMLSREDSQTCHLHKCCMFCTMQAHITWALHSPGHVIQPSQVLAAGFHRGEQEDAHEFLMFTVDAMKKACLPGHKQLDHHSKDTTLIHQIFGAYWRSQIKYLHCHGVSDTFDPYLDIALDIQAAQSVKQALEQLVKPKELNGENAYHCGLCLQKAPASKTLTLPTSAKVLILVLKRFSDVTGNKLAKNVQYPKCRDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASGITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRPATQGELKRDHPCLQVPELDEHLVERATQESTLDHWKFPQEQNKTKPEFNVRKVEGTLPPNVLVIHQSKYKCGMKNHHPEQQSSLLNLSSTKPTDQESMNTGTLASLQGSTRRSKGNNKHSKRSLLVCQ", "length": 530 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CW02-1", "protein_name": "Lymphocyte antigen 6C1", "gene_name": "Ly6c1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTSHTTKSCVLILLVALLCAERAQGLQCYECYGVPIETSCPAVTCRASDGFCIAQNIELIEDSQRRKLKTRQCLSFCPAGVPIRDPNIRERTSCCSEDLCNAAVPTAGSTWTMAGVLLFSLSSVVLQTLL", "length": 131 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DKL4-1", "protein_name": "Spliceosome-associated protein 130 A", "gene_name": "SAP130A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DKL6-1", "protein_name": "Spliceosome-associated protein 130 B", "gene_name": "SAP130B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MYLYSLTLQQATGIVCAINGNFSGGKTQEIAVARGKILDLLRPDENGKIQTIHSVEVFGAIRSLAQFRLTGAQKDYIVVGSDSGRIVILEYNKEKNVFDKVHQETFGKSGCRRIVPGQYVAVDPKGRAVMIGACEKQKLVYVLNRDTTARLTISSPLEAHKSHTICYSLCGVDCGFDNPIFAAIELDYSEADQDPTGQAASEAQKHLTFYELDLGLNHVSRKWSNPVDNGANMLVTVPGGADGPSGVLVCAENFVIYMNQGHPDVRAVIPRRTDLPAERGVLVVSAAVHKQKTMFFFLIQTEYGDVFKVTLDHNGDHVSELKVKYFDTIPVASSICVLKLGFLFSASEFGNHGLYQFQAIGEEPDVESSSSNLMETEEGFQPVFFQPRRLKNLVRIDQVESLMPLMDMKVLNIFEEETPQIFSLCGRGPRSSLRILRPGLAITEMAVSQLPGQPSAVWTVKKNVSDEFDAYIVVSFTNATLVLSIGEQVEEVNDSGFLDTTPSLAVSLIGDDSLMQVHPNGIRHIREDGRINEWRTPGKRSIVKVGYNRLQVVIALSGGELIYFEADMTGQLMEVEKHEMSGDVACLDIAPVPEGRKRSRFLAVGSYDNTVRILSLDPDDCLQILSVQSVSSAPESLLFLEVQASIGGDDGADHPANLFLNSGLQNGVLFRTVVDMVTGQLSDSRSRFLGLKPPKLFSISVRGRSAMLCLSSRPWLGYIHRGHFHLTPLSYETLEFAAPFSSDQCAEGVVSVAGDALRIFMIDRLGETFNETVVPLRYTPRKFVLHPKRKLLVIIESDQGAFTAEEREAARKECFEAGGVGENGNGNADQMENGADDEDKEDPLSDEQYGYPKAESEKWVSCIRVLDPKTATTTCLLELQDNEAAYSVCTVNFHDKEYGTLLAVGTVKGMQFWPKKNLVAGFIHIYRFVEDGKSLELLHKTQVEGVPLALCQFQGRLLAGIGPVLRLYDLGKKRLLRKCENKLFPNTIISIQTYRDRIYVGDIQESFHYCKYRRDENQLYIFADDCVPRWLTASHHVDFDTMAGADKFGNVYFVRLPQDLSEEIEEDPTGGKIKWEQGKLNGAPNKVDEIVQFHVGDVVTCLQKASMIPGGSESIMYGTVMGSIGALHAFTSRDDVDFFSHLEMHMRQEYPPLCGRDHMAYRSAYFPVKDVIDGDLCEQFPTLPMDLQRKIADELDRTPAEILKKLEDARNKII", "length": 1214 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P0DML3-1", "protein_name": "Chorionic somatomammotropin hormone 2", "gene_name": "CSH2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGSRTSLLLAFALLCLPWLQEAGAVQTVPLSRLFDHAMLQAHRAHQLAIDTYQEFEETYIPKDQKYSFLHDSQTSFCFSDSIPTPSNMEETQQKSNLELLRISLLLIESWLEPVRFLRSMFANNLVYDTSDSDDYHLLKDLEEGIQTLMGRLEDGSRRTGQILKQTYSKFDTNSHNHDALLKNYGLLYCFRKDMDKVETFLRMVQCRSVEGSCGF", "length": 217 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DMV2-1", "protein_name": "Cancer/testis antigen family 45 member A9", "gene_name": "CT45A9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKEKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETAFSPKSQQEINADIKRQLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DOV1-1", "protein_name": "Interferon-activable protein 211", "gene_name": "Ifi211", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLRGLECINKHYFSLFKSLLARDLNLERDNQEQYTTIQIANMMEEKFPADSGLGKLIEFCEEVPALRKRAEILKKERSEVTGETSLEKNGQEAGPATPTSTTSHMLASERGETSATQEETSTAQAGTSTAQAGTSTAQAGTSTAQKRKSMREEETGVKKSKAAKEPDQPPCCEEPTAMCQSPILHSSSSASSNILSAKNQKSQPQNQNIPRGAVLHSEPLTVMVLTATDPFEYESPEHEVKNMFHATVATVSQYFHVKVFNIDLKEKFTKNNFITISNYFESKGILEINETSSVLEAAPKQMIEVPNCITRNANASPKICDIQKGTSGTVFYGVFTLHKKKVKTQNTSYEIKDGSGSIEVVGSGQWHNINCKEGDKLHLFCFHLKRERGQPKLVCGDHSFVKVTKAGKKKEASTVQ", "length": 425 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0DTA3-1", "protein_name": "Speedy protein E11", "gene_name": "SPDYE11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVSGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD3-1", "protein_name": "Speedy protein E14", "gene_name": "SPDYE14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DUD4-1", "protein_name": "Speedy protein E15", "gene_name": "SPDYE15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQILGKIMMSHQPQPQEERSPQRSTSGYPLQEVVDDEVLGPSAPGVDPSPPRRSLGWKRKRECLDESDDEPEKELAPEPEETWVAETLCGLKMKAKRRRVSLVLPEYYEAFNRLLEDPVIKRLLAWDKDLRVSDKYLLAMVIAYFSRAGLPSWQYQRIHFFLALYLANDMEEDDEAPKQNIFYFLYEETRSHIPLLSELWFQLCRYMNPRARKNCSQIALFRKYRFHFFCSMRCRAWVSLEELEEIQAYDPEHWVWARDRAHLS", "length": 265 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW11-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 6", "gene_name": "TAF11L6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW12-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 7", "gene_name": "TAF11L7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW13-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 8", "gene_name": "TAF11L8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0DW14-1", "protein_name": "TATA-box-binding protein-associated factor 11-like protein 10", "gene_name": "TAF11L10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METGRQTGVSAEMLAMPRGLKGSKKDGIPEDLDGNLEAPRDQEGELRSEDVMDLTEGDSEASASAPPAAKRRKTHTKGKKESKPTVDAEEAQRMTTLLSAMSEEQLSRYEVCRRSAFPRARVAGLMRAITGSSVSENAAIAMAGIAKLFVGEVVEEALDVCEMWGETPPLQPKHLREAVRRLKPKGLFPNSNCKRIMF", "length": 198 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11588-1", "protein_name": "Major urinary protein 1", "gene_name": "Mup1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLENSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAQLCEKHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11589-1", "protein_name": "Major urinary protein 2", "gene_name": "Mup2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKMLLLLCLGLTLVCVHAEEASSTGRNFNVEKINGEWHTIILASDKREKIEDNGNFRLFLEQIHVLEKSLVLKFHTVRDEECSELSMVADKTEKAGEYSVTYDGFNTFTIPKTDYDNFLMAHLINEKDGETFQLMGLYGREPDLSSDIKERFAKLCEEHGILRENIIDLSNANRCLQARE", "length": 180 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P13255-1", "protein_name": "Glycine N-methyltransferase", "gene_name": "Gnmt", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDSVYRTRSLGVAAEGIPDQYADGEAARVWQLYIGDTRSRTAEYKAWLLGLLRQHGCHRVLDVACGTGVDSIMLVEEGFSVTSVDASDKMLKYALKERWNRRKEPAFDKWVIEEANWLTLDKDVPAGDGFDAVICLGNSFAHLPDSKGDQSEHRLALKNIASMVRPGGLLVIDHRNYDYILSTGCAPPGKNIYYKSDLTKDITTSVLTVNNKAHMVTLDYTVQVPGAGRDGAPGFSKFRLSYYPHCLASFTELVQEAFGGRCQHSVLGDFKPYRPGQAYVPCYFIHVLKKTG", "length": 293 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13675-1", "protein_name": "Y-linked testis-specific protein 1", "gene_name": "Ssty1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLMKKRRRKSSSNTLRNIVSCRISHSWKEGNEPVTQWKAIVLDQLPTNPSLYFVKYDGIDSIYVLELYSDDRILNLKVLPPIVVFPQVRDAHLARALVGRAVQHKFERKDGSEVNWRGVVLAQVPIMKDLFYITYKKDPALYAYQLLDDYKEGNLHMIPDTPPAEERSGDDSDVLIGNWVEYTRKDGSKKFGKVVYQVLANPSVYFIKFHGDIHIYVYTMVPKILEVEKS", "length": 232 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P15515-1", "protein_name": "Histatin-1", "gene_name": "HTN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN", "length": 57 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16374-1", "protein_name": "Zinc finger protein 60", "gene_name": "Zfp60", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSSSQHMVCGSVTFRDVAVDFSQEEWACLDATQKVLYRNIMLETYSNLVAVVGRCIPKPDLIVLLEPEKEPWMAVKKETGRPSQGLETGFEAENRSPKNHVYNKKLPKQTIQQLSKTSDVQGVSVSNGPGYSVIKEPQNYQEGDANRNITNKKEMSTYTSKTLAHNKEKPYKCKDCGKCFGCKSNLHQHESIHTGEKPYECKDCGKTFRLPQMLSRHQKSHSDERPFECNICGKSFHLPTLLQYHKNIHTGLKPFECEECGKSFKSFNRISTLFQHRTIHAGMKPYKCNVCGKAFNRRSNLLQHQKIHSEDRPFHCKVCGKAFTVLAQLTRHENIHTEDKSFECKQCGKIFSNGSYLLRHYDTHTNEKPFECNICGKAFRLHLYLSEHQKTHTDEKPFKCKLCESAFRRKYQLSEHQRIHTDGKPYQCKDCWEFFRRRSNFIEHQSIHTGKKPFECKDCGKVFRLNIHLIRHQRFHSDEKPFECKECGKAFHFSSQLNNHKTSHTGQTPFECKECGKSFKRVSSLVEHRIIHSGVKPYKCNACGRAFNRRSNLMQHEKIHSDERPFECKDCGKAFTVLAQLTRHQTIHNGKKSYECEQCGSAFRLPYQLTQHQRIHYDVKPFQCKECGRAFVRSTGLRIHERIHTGEKPFQCKECGEAFQYHYQFLGHFRIHTGKNPYECSECGKYFTYGRDLKVHQSIHNLEKP", "length": 707 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20816-1", "protein_name": "Cytochrome P450 4A2", "gene_name": "Cyp4a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGFSVFSPTRSLDGVSGFFQGAFLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWGHNLKDREFQQVLTWVEKFPGACLQWLSGSTARVLLYDPDYVKVVLGRSDPKPYQSLAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILKPYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYVSLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLIFFRVRSAFYGNSIIYNMSSDGRLSRRACQIAHEHTDGVIKTRKAQLQNEEELQKARKKRHLDFLDILLFAKMEDGKSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGDGTSVTWDHLDQMPYTTMCIKEALRLYSPVPSVSRELSSPVTFPDGRSIPKGIRVTILIYGLHHNPSYWPNPKVFDPSRFSPDSPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRFELLPDPTRIPVPMPRLVLKSKNGIHLRLKKLR", "length": 504 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P21571-1", "protein_name": "ATP synthase peripheral stalk subunit F6, mitochondrial", "gene_name": "Atp5pf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVQRIFRLSSVLRSAVSVHLRRNIGVTAVAFNKELDPVQKLFLDKIREYKAKRLASGGPVDTGPEYQQEVDRELFKLKQMYGKGEMDKFPTFNFEDPKFEVLDKPQS", "length": 108 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22237-1", "protein_name": "NADH-ubiquinone oxidoreductase subunit 9", "gene_name": "nad9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKDYKNELKVKINLGEHLRLSIPGLVKKIMYKTHYLEIQVEKEKMLTVLKYLKEASKYQCNMLLDIVCVDCLNIEEIKIGRFKLIYVLNSIYNNTRVHLSTYVENNGIIETTSGLFESSVWLEREIWDMFGIYFEKHPDLRRILTDYGFVGYPLKKDFPITGYLEVYYDVNDKKIIYKPIELMQEYRNYNFGAVWGDYERKVYLENIIK", "length": 209 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "P22283-1", "protein_name": "Cystatin-related protein 2", "gene_name": "Crp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYKTLCGTQLLLAIFVLFLNFSHATAKGTRGPMEIFKKNFMEKNKLNDVYDIFKFLYNKFSHDTYLSNIKNQSFTMNTWGFGEIEVVKTKCRKIDSDFYKCSFQWEFCNIKRTPGVTIYYITLPGSVRCRKLLSKLVNCPFEEQTEQLKREICYFQLYPDYIEQNIRSVRFNCYTK", "length": 176 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23266-1", "protein_name": "Olfactory receptor 1f45", "gene_name": "Or1f45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSTNQSSVTEFLLLGLSRQPQQQQLLFLLFLIMYLATVLGNLLIILAIGTDSRLHTPMYFFLSNLSFVDVCFSSTTVPKVLANHILGSQAISFSGCLTQLYFLAVFGNMDNFLLAVMSYDRFVAICHPLHYTTKMTRQLCVLLVVGSWVVANMNCLLHILLMARLSFCADNMIPHFFCDGTPLLKLSCSDTHLNELMILTEGAVVMVTPFVCILISYIHITCAVLRVSSPRGGWKSFSTCGSHLAVVCLFYGTVIAVYFNPSSSHLAGRDMAAAVMYAVVTPMLNPFIYSLRNSDMKAALRKVLAMRFPSKQ", "length": 313 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24049-1", "protein_name": "Large ribosomal subunit protein uL22", "gene_name": "Rpl17", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRYSLDPENPTKSCKSRGSNLRVHFKNTRETAQAIKGMHIRKATKYLKDVTLKKQCVPFRRYNGGVGRCAQAKQWGWTQGRWPKKSAEFLLHMLKNAESNAELKGLDVDSLVIEHIQVNKAPKMRRRTYRAHGRINPYMSSPCHIEMILTEKEQIVPKPEEEVAQKKKISQKKLKKQKLMARE", "length": 184 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24868-1", "protein_name": "G2/mitotic-specific cyclin-1", "gene_name": "CLB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSRSLLVENSRTINSNEEKGVNESQYILQKRNVPRTILGNVTNNANILQEISMNRKIGMKNFSKLNNFFPLKDDVSRADDFTSSFNDSRQGVKQEVLNNKENIPEYGYSEQEKQQCSNDDSFHTNSTALSCNRLIYSENKSISTQMEWQKKIMREDSKKKRPISTLVEQDDQKKFKLHELTTEEEVLEEYEWDDLDEEDCDDPLMVSEEVNDIFDYLHHLEIITLPNKANLYKHKNIKQNRDILVNWIIKIHNKFGLLPETLYLAINIMDRFLCEEVVQLNRLQLVGTSCLFIASKYEEIYSPSIKHFAYETDGACSVEDIKEGERFILEKLDFQISFANPMNFLRRISKADDYDIQSRTLAKFLMEISIVDFKFIGILPSLCASAAMFLSRKMLGKGTWDGNLIHYSGGYTKAKLYPVCQLLMDYLVGSTIHDEFLKKYQSRRFLKASIISIEWALKVRKNGYDIMTLHE", "length": 471 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25389-1", "protein_name": "Probable serine/threonine-protein kinase KCC4", "gene_name": "KCC4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTVANTETHSAAKPSSTIGPWKLGETLGFGSTGKVQLAQHERTGHRTAVKVISKSIFNNNGNHSNDDSVLPYNIEREIVIMKLLSHPNVLSLYDVWETNNNLYLILEYAEKGELFNLLVDHGPLPEREAINCFRQIIIGISYCHALGIVHRDLKPENLLLDSFYNIKIADFGMAALQTDADLLETSCGSPHYAAPEIVSGLPYEGFASDVWSCGVILFALLTGRLPFDEENGNVRDLLLKVQKGQFEMPNDTEISRDAQDLIGKILVVDPRQRIKIRDILSHPLLKKYQTIKDSKSIKDLPRENTYLYPLADSNNHTSASIDDSILQNLVVLWHGRHADDIVSKLKENGTNKEKILYALLYRFKLDSVRGSNKKNRNKIKKTKKNKRSSTLSSSSSLLLNNRSIQSTPRRRTSKRHSREFSSSRKRSSFLLSSNPTDSSPIPLRSSKRITHINVASANTQATPSGVPNPHKRNSKKRSSKRLSYMPNTKRSSLTSKSLSNFTNLIDDDDWEYIEKDAKRTSSNFATLIDEIFEPEKFELAKREKAELQRKVQEAKRQSVNAQKINEDEFGSEVSDGMKELKKINDKVSSPLINYEFSQQELLQDIDTLLTNRYQLSSYTRPISRLDPGLTPVTETLPNNLKEKTALLQDTEKKIIETIRRSKFLGSLLNVRGGLSPGKSELAPIEESPIVSTTPLIYNDRMEPRRISDVEVPHFTRKSKHFTTANNRRSVLSLYAKDSIKDLNEFLIKEDPDLPPQGSTDNESRSEDPEIAESITDSRNIQYDEDDSKDGDNVNNDNILSDFPQGVGISQEYDMKDKNPNQSPISKSAEPTLVVKLPSLSSFQGKNASGLGLYQREPSKVTLPSLTSNNSSVGENIEDGAEKGTESEKIAASLSDDDLKEDNDKKDNDTVNAPTTVKKPPNSVLLKKFSKGKILELEIHAKIPEKRLYEGLHKLLEGWKQYGLKNLVFNITNMIITGKLVNDSILFLRSTLFEIMVLPNGDGRSLIKFNKKTGSTKTLTKLATEIQIILQKEGVLDK", "length": 1037 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P28312-1", "protein_name": "Alpha-defensin 5", "gene_name": "Defa5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTFVLLSALVLLAFQVQADPIHKTDEETNTEEQPGEEDQAVSISFGGQEGSALHEELSKKLICYCRIRGCKRRERVFGTCRNLFLTFVFCCS", "length": 93 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P28742-1", "protein_name": "Kinesin-like protein KIP1", "gene_name": "KIP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARSSLPNRRTAQFEANKRRTIAHAPSPSLSNGMHTLTPPTCNNGAATSDSNIHVYVRCRSRNKREIEEKSSVVISTLGPQGKEIILSNGSHQSYSSSKKTYQFDQVFGAESDQETVFNATAKNYIKEMLHGYNCTIFAYGQTGTGKTYTMSGDINILGDVQSTDNLLLGEHAGIIPRVLVDLFKELSSLNKEYSVKISFLELYNENLKDLLSDSEDDDPAVNDPKRQIRIFDNNNNNSSIMVKGMQEIFINSAHEGLNLLMQGSLKRKVAATKCNDLSSRSHTVFTITTNIVEQDSKDHGQNKNFVKIGKLNLVDLAGSENINRSGAENKRAQEAGLINKSLLTLGRVINALVDHSNHIPYRESKLTRLLQDSLGGMTKTCIIATISPAKISMEETASTLEYATRAKSIKNTPQVNQSLSKDTCLKDYIQEIEKLRNDLKNSRNKQGIFITQDQLDLYESNSILIDEQNLKIHNLREQIKKFKENYLNQLDINNLLQSEKEKLIAIIQNFNVDFSNFYSEIQKIHHTNLELMNEVIQQRDFSLENSQKQYNTNQNMQLKISQQVLQTLNTLQGSLNNYNSKCSEVIKGVTEELTRNVNTHKAKHDSTLKSLLNITTNLLMNQMNELVRSISTSLEIFQSDSTSHYRKDLNEIYQSHQQFLKNLQNDIKSCLDSIGSSILTSINEISQNCTTNLNSMNVLIENQQSGSSKLIKEQDLEIKKLKNDLINERRISNQFNQQLAEMKRYFQDHVSRTRSEFHDELNKCIDNLKDKQSKLDQDIWQKTASIFNETDIVVNKIHSDSIASLAHNAENTLKTVSQNNESFTNDLISLSRGMNMDISSKLRSLPINEFLNKISQTICETCGDDNTIASNPVLTSIKKFQNIICSDIALTNEKIMSLIDEIQSQIETISNENNINLIAINENFNSLCNFILTDYDENIMQISKTQDEVLSEHCEKLQSLKILGMDIFTAHSIEKPLHEHTRPEASVIKALPLLDYPKQFQIYRDAENKSKDDTSNSRTCIPNLSTNENFPLSQFSPKTPVPVPDQPLPKVLIPKSINSAKSNRSKTLPNTEGTGRESQNNLKRRFTTEPILKGEETENNDILQNKKLHQ", "length": 1111 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P29314-1", "protein_name": "Small ribosomal subunit protein uS4", "gene_name": "Rps9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVARSWVCRKTYVTPRRPFEKSRLDQELKLIGEYGLRNKREVWRVKFTLAKIRKAARELLTLDEKDPRRLFEGNALLRRLVRIGVLDEGKMKLDYILGLKIEDFLERRLQTQVFKLGLAKSIHHARVLIRQRHIRVRKQVVNIPSFIVRLDSQKHIDFSLRSPYGGGRPGRVKRKNAKKGQGGAGAGDDEEED", "length": 194 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33579-1", "protein_name": "Prolactin-8A5", "gene_name": "Prl8a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELALSQPSFFGTLLMLVVSNLLLWEKAASIPACMVEDGGCWDPLREAFNSATQRAETLRNLSDQLYVEFFQNQFSSRQFADLSSQLIRKDETVLKAGTYCHSNRAKPKSRGVNIDIEEYLKMSINFCGFMDQPLFHLVIELSAMEGVPETILSKAKDLEENNRQLLDDLRWILTKVFPTAEIKEEFPSWDYLSFLKSSNKNHKFLAIFNLSSCLDYDTQVHYTLSQILNCLITGKDC", "length": 238 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36006-1", "protein_name": "Myosin-3", "gene_name": "MYO3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MAVIKKGARRKDVKEPKKRSAKIKKATFDANKKKEVGISDLTLLSKISDESINENLKKRFKNGIIYTYIGHVLISVNPFRDLGIYTNAVLESYKGKNRLEVPPHVFAIAESMYYNLKSYNENQCVIISGESGAGKTEAAKRIMQYIAAASNSHSESIGKIKDMVLATNPLLESFGCAKTLRNNNSSRHGKYLEIKFNSQFEPCAGNITNYLLEKQRVVGQIKNERNFHIFYQFTKGASDTYKQMFGVQMPEQYIYTAAAGCTTADTIDDVKDYEGTLEAMRTIGLVQEEQDQIFRMLAAILWIGNISFIENEEGNAQVGDTSVTDFVAYLLQVDASLLVKCLVERIMQTSHGMKRGSVYHVPLNPVQATAVRDALAKAIYNNLFDWIVDRVNVSLQAFPGADKSIGILDIYGFEIFEHNSFEQICINYVNEKLQQIFIQLTLKAEQETYEREKIKWTPIKYFDNKVVCDLIEAKNPPGILAAMNDSIATAHADSNAADQAFAQRLNLFNSNPYFELRANKFVIKHYAGDVTYDINGITDKNKDQLQKDLIELIGTTTNTFLSTIFPDDVDKDSKRRPPTAGDKIIKSANELVETLSKAEPSYIRTIKPNQTKSPNDYDDHQVLHQVKYLGLQENVRIRRAGFAYRQTFEKFVERFYLLSPDCSYAGDYTWDGDTLEAVKLILRDAMIPEKEFQLGVTSVFIKTPESLFALEDMRDKYWYNMAARIQRAWRRFLQRRIDAAIKIQRTIREKKGGNKYVKLRDYGTKLLAGKKERRSMSLLGYRAFMGDYLSCNESKTKGSYIRRQVGIKDKVVFSIKGECLHSKFGRSAQRLKKVFILTKKTFYIIGQTREQNAMKYTQDYKIDVGKIKQVSLTNLQDDWMGVILVNSTQSDPLINTPFKTELMTRLKKLNEKIMIKVGPTIEYHKQPNKLHTVRSKISDSAPKYGDIYKSSTIYVRRGHPANSKSNKKPKNPGGLSGKPIKSKKSKHKSTHKHTHSHRSHRDAAKKQPLPSQKPVNPLSLAATAAQAAYNPKPDKTVPIKSSAIPAAKVSSKHSSKPSSKEKVAVKKASSSHKSSSAKQNQVSMPPSKGVEKNKEPLKETTATATANIPIPPPPPPMGQPKDPKFEAAYDFPGSGSSSELPLKKGDIVFISRDEPSGWSLAKLLDGSKEGWVPTAYMTPYKDTRNTVPVAATGAVNDVTNQKSSQIDNTISSAQEGVQFGSATVGPTSDNQSNPVGTFSDGLASALAARANKMRAESADDDDNDDGDDDDDW", "length": 1272 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P36046-1", "protein_name": "Mitochondrial intermembrane space import and assembly protein 40", "gene_name": "MIA40", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLRNLVVRNACRNRPSIQVARGLCRHQTRRLMASSPQFGRNSNQEKTAGFIMGILSMAGALYFIAPNRKPLFASRKVESDKTAEEELSSGGEQSPENEDDNNSKSDENGDDNDSKNDETEAGPQLGGDKIGASKVAEDGELVVLAEEDNKSSEDKDTDESKVSTKDDEQSNEDNATANNQKDENISSENSEENTSDKTLDNNAGSSEKKDPEHSDDEKSQQGQSDDKTTTEDNNGEEESSKKTVSDSENSAKQSESSDEEKEELRKQEEKQMGPTEEEVQHEGAYNPDTGEINWDCPCLGGMAHGPCGEEFKSAFSCFVYSEAEPKGIDCVEKFQHMQDCFRKYPEHYAEQLKETSDDEEPQDKVKVNTIESAPNVSSAKENAAKKAEQSDVKKEPLNEESKP", "length": 403 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P37106-1", "protein_name": "Signal recognition particle subunit SRP54 1", "gene_name": "SRP-54A", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVLAELGGRITRAIQQMNNVTIIDEKVLNDFLNEITRALLQSDVSFGLVEKMQTNIKKIVNLDDLAAGHNKRLIIEQAIFKELCRMLDPGKPAFAPKKAKPSVVMFVGLQGAGKTTTCTKYAYYHQKKGYKAALVCADTFRAGAFDQLKQNATKAKIPFYGSYTESDPVKIAVEGVDRFKKEKCDLIIVDTSGRHKQAASLFEEMRQVAEATEPDLVIFVMDSSIGQAAFEQAEAFKETVSVGAVIITKMDGHAKGGGALSAVAATKSPVIFIGTGEHMDEFEVFDVKPFVSRLLGKGDWSGLVDKLQEVVPKDLQNELVENLSQGNFTLRSMYDQFQCSLRIPLNQLFSMLPGISAEMMPKGHGEESRVKMKRYMTMMDSMTNKELDSPNPKIFNESRIMRIARGSGRLVREVMEMLEEYKRIAKTMKGIKIPKNGDMSKVIPPQMLKQMGGMSGLQSLMKQMGSAKDMMGMFGGGGK", "length": 479 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "P38150-1", "protein_name": "Inactive deaminase YBR284W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVQNNESVFFVECDSYKESPSTSPIRLDDLDGNDAVSDQGLAFDGDVGITSQARVRNPRAQIFEDSNTDVVLHLDDLDMVPLNTKFDMQMEMGSPMAMPAETPPPVEPLKTKDLAYSSLAHLPSYFFEQTHFRIDRKCLLEMSKLRRNYLTISKQDALSCPQLHSRVAGGYLKPVKEKLFGIRHFLDLEESNTVNLLQDGNYMTELFNSQINIPTFKEFREDFEWCLKIIRDRSLSRFSEKRLQYLVNKFPVFQHLHSKEEMRQSKKVPHKDFYNCRKIDLNLLLSGCFSQWQLTEFIWTKLRKEPDRVIHQAFNGSHITLSQLFKVNFEETGQFFNGLKIIDDSFLEWYKVIYLAKYHLVNDEMEIHTGSHGKQLRYYLIAKTFLEFDNYINGEYLAELLKTFLIKPQEESKYQLCQLSVDFQFYLHYDNSDVDNWWMVFANWLNHYNIFSNNIRWNIRISRIYPELYHTGKVKNFQEYLNLIFKPLFNAENYLHKSLGPILLKFLSQVSSIDLCIQDTDNYIWKNFTAVSCLPKDWTSGGDNPTISQYMYYVYVNLTKLNHIRQALHQNTFTLRSSCSPTSMNRTSQFSNTLNFTEHTEAILNNFLLACGGFLNAENLWNAPPSLVYLFYLSQIPMVVAPLNSIVDSKPTMLQEQAPTGLVLEPSKPYKKNPFMKFFEMGFKISLSSESILYNNSYTKEPIIEEYSVAASIYRLHSADLCELLRNSVITSGFSSTLKNKWLGVSLASHDYFVENTGFVDKWYDCKPNTSLEHNVPIIRRQYRSSTLAGEWRLIIA", "length": 797 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40002-1", "protein_name": "Transcriptional regulator MIT1", "gene_name": "MIT1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDIEPTFKGYIEDEDDALLILQATLDGKLKHIPRRPYEIERPYLIVSGSIFVFIEEISGIKRWTDGVSWSPSRISGKFLIYKELDKENAGSNANATSSGSTDSAVITDGTSGARNNPSSSKIKLPPLKNHQFDLPPTMGHSSFESEQDTSISPSNRSNLPLKYTGLVKKTISVKLKRPPFNSIENLHIVSYYSVKDIKQNCLVTPKASPFLKDVRPSQELIVAMGNTTLGNVKNNSTTTGNGPNNINNKSNSSTPLNTVISTNNNSANINAAGSNQFTSANKNYYYKNDESSGYPITQFAPALPSTTLMYTANPPYITQSPDNTNATGMNTHVNNNNNNSNNSSNSNNSNNNNNNNNNNNNNNNNNINNINNVNTNAGNGNNPNRFHNASFAYNTTGDFINPQQQGQISYPFYYTTIPINNPNYYTTQPPNPVTNASTNENQGYSTSSTQHPYYGHPTESQSASAAAGATGTPGTAENVLPVSSMQPLLHQANNNSASSATSTAPYPVYSMNVNVPYYNSSASAYKRAQENTTSNTNAEPSGATSTNSGTMLSNPAYANSQYTPSQVYYQGFPQYAMASAQNPSMYQHQHQHPLPTVYPIATPQQNIMSSGHTLSTIGSDPQHHHYQQEPNDHKNFAMGHANNNILNITNNDTMNNLNTNTSTTTQ", "length": 666 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P42222-1", "protein_name": "Enolase-related protein 3", "gene_name": "ERR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSITKVHARTVYDSRGNPTVEVEITTENGLFRAIVPSGASTGIHEAVELRDGNKSEWMGKGVTKAVSNVNSIIGPALIKSDLCVTNQKGIDELMISLDGTSNKSRLGANAILGVSLCVARAAAAQKGITLYKYIAELADARQDPFVIPVPFFNVLNGGAHAGGSLAMQEFKIAPVGAQSFAEAMRMGSEVYHHLKILAKEQYGPSAGNVGDEGGVAPDIDTAEDALDMIVKAINICGYEGRVKVGIDSAPSVFYKDGKYDLNFKEPNSDPSHWLSPAQLAEYYHSLLKKYPIISLEDPYAEDDWSSWSAFLKTVNVQIIADDLTCTNKTRIARAIEEKCANTLLLKLNQIGTLTESIEAANQAFDAGWGVMISHRSGETEDPFIADLVVGLRCGQIKSGALSRSERLAKYNELLRIEEELGDDCIYAGHRFHDGNKL", "length": 437 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P43356-1", "protein_name": "Melanoma-associated antigen 2", "gene_name": "MAGEA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQQTASSSSTLVEVTLGEVPAADSPSPPHSPQGASSFSTTINYTLWRQSDEGSSNQEEEGPRMFPDLESEFQAAISRKMVELVHFLLLKYRAREPVTKAEMLESVLRNCQDFFPVIFSKASEYLQLVFGIEVVEVVPISHLYILVTCLGLSYDGLLGDNQVMPKTGLLIIVLAIIAIEGDCAPEEKIWEELSMLEVFEGREDSVFAHPRKLLMQDLVQENYLEYRQVPGSDPACYEFLWGPRALIETSYVKVLHHTLKIGGEPHISYPPLHERALREGEE", "length": 314 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43357-1", "protein_name": "Melanoma-associated antigen 3", "gene_name": "MAGEA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLEQRSQHCKPEEGLEARGEALGLVGAQAPATEEQEAASSSSTLVEVTLGEVPAAESPDPPQSPQGASSLPTTMNYPLWSQSYEDSSNQEEEGPSTFPDLESEFQAALSRKVAELVHFLLLKYRAREPVTKAEMLGSVVGNWQYFFPVIFSKASSSLQLVFGIELMEVDPIGHLYIFATCLGLSYDGLLGDNQIMPKAGLLIIVLAIIAREGDCAPEEKIWEELSVLEVFEGREDSILGDPKKLLTQHFVQENYLEYRQVPGSDPACYEFLWGPRALVETSYVKVLHHMVKISGGPHISYPPLHEWVLREGEE", "length": 314 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43537-1", "protein_name": "Uncharacterized membrane protein YFL067W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MESIILSIAIFIGVLLGTSVGAGSGSSISPDVDAGSGSRTSPDVDAGSGSRISAGVGTFSGSSTSPDVDAGSGSSTSPDVGAGSGSSISAGVGSRIGTGIGSRIGTGIGTGIGSRISTSIGSRISPDVGTSSGNRISTGVSTGISTTMNARVAVLITAAILSAPVTAIALLEARR", "length": 175 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P46162-1", "protein_name": "Beta-defensin 4", "gene_name": "DEFB4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLAVLFLVLSAGSGFTQRVRNPQSCRWNMGVCIPFLCRVGMRQIGTCFGPRVPCCRR", "length": 63 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P46169-1", "protein_name": "Beta-defensin 11", "gene_name": "DEFB11", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRLHHLLLALLFLVLSAGSGISGPLSCRRNGGVCIPIRCPGPMRQIGTCFGRPVKCCRSW", "length": 60 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P47102-1", "protein_name": "ARF guanine-nucleotide exchange factor 1", "gene_name": "GEA1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MHDVPMETVLAVNPATMIVKECINLCSAMNKQSRDKSQTSVAALLGGGSDIFLSQSDSFVDSFHNLPTSSYHDPLISGLVQLRLKINDLKGLDSLNALELLKPFLEIVSASSVSGYTTSLALDSLQKVFTLKIINKTFNDIQIAVRETVVALTHCRFEASKQISDDSVLLKVVTLLRDIITSSFGDYLSDTIIYDVLQTTLSLACNTQRSEVLRKTAEVTIAGITVKLFTKLKLLDPPTKTEKYINDESYTDNNLKDDIIGTTTSDNDLSSTDDDSAVADDNKNEKPVQQVIREQENDEETAEKAENVEPNYGITVIKDYLGLLLSLVMPENRMKHTTSAMKLSLQLINAAIEISGDKFPLYPRLFSLISDPIFKSVLFIIQSSTQYSLLQATLQLFTSLVVILGDYLPMQIELTLRRIFEILEDTTISGDVSKQKPPAIRELIIEQLSILWIHSPAFFLQLFVNFDCNLDRSDLSIDFIKELTKFSLPAAAVNTSNNIPPICLEGVLSLIENIYNDLQRFDRAEFVKNQKEIDILKQRDRKTEFILCVETFNEKAKKGIQMLIEKGFIDSDSNRDIASFLFLNNGRLNKKTIGLLLCDPKKTSLLKEFIDLFDFKGLRVDEAIRILLTKFRLPGESQQIERIVEAFSSKYSADQSNDKVELEDKKAGKNGSESMTEDDIIHVQPDADSVFVLSYSIIMLNTDSHNPQVKDHMTFDDYSNNLRGCYNGKDFPRWYLHKIYTSIKVKEIVMPEEHHGNERWFEDAWNNLISSTSVMTEMQRDFTNPISKLAQIDILQYEKAIFSNVRDIILKTLFKIFTVASSDQISLRILDAISKCTFINYYFSFDQSYNDTVLHLGEMTTLAQSSAKAVELDVDSIPLVEIFVEDTGSKISVSNQSIRLGQNFKAQLCTVLYFQIIKEISDPSIVSTRLWNQIVQLILKLFENLLMEPNLPFFTNFHSLLKLPELPLPDPDISIRKAKMSRSLLSTFASYLKGDEEPSEEDIDFSIKAFECVKASHPLSSVFENNQLVSPKMIETLLSSLVIEKTSENSPYFEQELLFLLEISIILISEASYGQEFGALIADHMINISNLDGLSKEAIARLASYKMFLVSRFDNPRDILSDLIEHDFLVKNEIFNTKYYESEWGKQVINDLFTHLNDVKYNERALKNVKFWNFLRILISAKDRQFAVYTFLEKYIQNGDIFVDDGNFMNILSLLDEMSCAGAVGTKWEQNYENSVEDGCEAPESNPYRSIIDLSSRSINITADLLSTVGRSNSALNKNEIIAAIQGLAHQCLNPCDELGMQALQALENILLSRASQLRTEKVAVDNLLETGLLPIFELDEIQDVKMKRITSILSVLSKIFLGQLVEGVTSNETFLRVLNVFNKYVDDPTVERQLQELIISKREIEKE", "length": 1408 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P53563-1", "protein_name": "Bcl-2-like protein 1", "gene_name": "Bcl2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQSNRELVVDFLSYKLSQKGYSWSQFSDVEENRTEAPEETEPERETPSAINGNPSWHLADSPAVNGATGHSSSLDAREVIPMAAVKQALREAGDEFELRYRRAFSDLTSQLHITPGTAYQSFEQVVNELFRDGVNWGRIVAFFSFGGALCVESVDKEMQVLVSRIASWMATYLNDHLEPWIQENGGWDTFVDLYGNNAAAESRKGQERFNRWFLTGMTVAGVVLLGSLFSRK", "length": 233 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56840-1", "protein_name": "Protein TCL1B1", "gene_name": "Tcl1b1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAFDPLGPLPVYLVSVRLGIYEDEHHRVWIVANVETSHSSHGNRRRTHVTVHLWKLIPQQVIPFNPLNYDFLPTTWKLESRNIYWATDGTHWRLLDHSQLGDTEQLILMLVLG", "length": 116 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56841-1", "protein_name": "Protein TCL1B2", "gene_name": "Tcl1b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAGFYPPRLLPQVLISTGPGFYEDEHHRLWMVAKLETCSHSPYCNKIETCVTVHLWQMTRYPQEPAPYNPMNYNFLPMTWRLASMNTYRGTDAMHWRLLNHSQVGDTVQLILMLE", "length": 117 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56842-1", "protein_name": "Protein TCL1B3", "gene_name": "Tcl1b3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVHFPWMPFPPRFLVCTRDDIYEDENGRQWVVAKVETSRSPYGSRIETCITVHLQHMTTIPQEPTPQQPINNNSLPTMWRLESMNTYTGTDGTYWRLLDHSQMGDTLQLILDIVICEVD", "length": 122 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56844-1", "protein_name": "Protein TCL1B4", "gene_name": "Tcl1b4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADSVRFPCMPFPPCFLVCTRDDIYEDEHGRQWVAAKVETSSHSPYCSKIETCVTVHLWQMTTLFQEPSPDSLKTFNFLPRTWRLESRNTYRGADAMHWRLVNHSQFYGTEELVLMLDSR", "length": 120 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P59528-1", "protein_name": "Taste receptor type 2 member 123", "gene_name": "Tas2r123", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSQKINYSHLFTFSITLYVEIVTGILGHGFIALVNIMDWVKRRRISSVDQILTALALTRFIYVLSMLICILLFMLCPHLPRRSEMLSAMGIFWVVNSHFSIWLTTCLGVFYFLKIANFSNSFFLYLKWRVKKVILIIILASLIFLTLHILSLGIYDQFSIAAYVGNMSYSLTDLTQFSSTFLFSNSSNVFLITNSSHVFLPINSLFMLIPFTVSLVAFLMLIFSLWKHHKKMQVNAKQPRDVSTMAHIKALQTVFSFLLLYAIYLLFLIIGILNLGLMEKIVILIFDHISGAVFPISHSFVLILGNSKLRQASLSVLPCLRCQSKDMDTMGL", "length": 333 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P61314-1", "protein_name": "Large ribosomal subunit protein eL15", "gene_name": "Rpl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAYKYIQELWRKKQSDVMRFLLRVRCWQYRQLSALHRAPRPTRPDKARRLGYKAKQGYVIYRIRVRRGGRKRPVPKGATYGKPVHHGVNQLKFARSLQSVAEERAGRHCGALRVLNSYWVGEDSTYKFFEVILIDPFHKAIRRNPDTQWITKPVHKHREMRGLTSAGRKSRGLGKGHKFHHTIGGSRRAAWRRRNTLQLHRYR", "length": 204 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62246-1", "protein_name": "Small ribosomal subunit protein uS8", "gene_name": "Rps15a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVRMNVLADALKSINNAEKRGKRQVLIRPCSKVIVRFLTVMMKHGYIGEFEIIDDHRAGKIVVNLTGRLNKCGVISPRFDVQLKDLEKWQNNLLPSRQFGFIVLTTSAGIMDHEEARRKHTGGKILGFFF", "length": 130 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62425-1", "protein_name": "Large ribosomal subunit protein eL8", "gene_name": "Rpl7a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKGKKAKGKKVAPAPAVVKKQEAKKVVNPLFEKRPKNFGIGQDIQPKRDLTRFVKWPRYIRLQRQRAILYKRLKVPPAINQFTQALDRQTATQLLKLAHKYRPETKQEKKQRLLARAEKKAAGKGDVPTKRPPVLRAGVNTVTTLVENKKAQLVVIAHDVDPIELVVFLPALCRKMGVPYCIIKGKARLGRLVHRKTCTTVAFTQVNSEDKGALAKLVEAIRTNYNDRYDEIRRHWGGNVLGPKSVARIAKLEKAKAKELATKLG", "length": 266 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62802-1", "protein_name": "Histone H4", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFGG", "length": 103 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P62963-1", "protein_name": "Profilin-1", "gene_name": "Pfn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGWNAYIDSLMADGTCQDAAIVGYKDSPSVWAAVPGKTFVSITPAEVGVLVGKDRSSFFVNGLTLGGQKCSVIRDSLLQDGEFTMDLRTKSTGGAPTFNVTVTMTAKTLVLLMGKEGVHGGLINKKCYEMASHLRRSQY", "length": 140 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62982-1", "protein_name": "Ubiquitin-ribosomal protein eS31 fusion protein", "gene_name": "Rps27a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQIFVKTLTGKTITLEVEPSDTIENVKAKIQDKEGIPPDQQRLIFAGKQLEDGRTLSDYNIQKESTLHLVLRLRGGAKKRKKKSYTTPKKNKHKRKKVKLAVLKYYKVDENGKISRLRRECPSDECGAGVFMGSHFDRHYCGKCCLTYCFNKPEDK", "length": 156 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70709-1", "protein_name": "Eosinophil cationic protein", "gene_name": "Rnase3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLKLLESRLCLLLSLGLVLMLASCQPPTPSQWFEIQHIYNRAYPRCNDAMRHRNRFTGHCKDINTFLHTSFASVVGVCGNRNIPCGNRTYRNCHNSRYRVSITFCNLTTPARIYTQCRYQTTRSRKFYTVGCDPRTPRDSPMYPVVPVHLDRIF", "length": 155 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81278-1", "protein_name": "Prolactin-releasing peptide", "gene_name": "Prlh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKTWLLCLLLLSLVLPGASSRAHQHSMETRTPDINPAWYTGRGIRPVGRFGRRRATPRDVTGLGQLSCLPLDGRTKFSQRG", "length": 83 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83883-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "Rpl36a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P83884-1", "protein_name": "Large ribosomal subunit protein eL42", "gene_name": "RPL36A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVNVPKTRRTFCKKCGKHQPHKVTQYKKGKDSLYAQGKRRYDRKQSGYGGQTKPIFRKKAKTTKKIVLRLECVEPNCRSKRMLAIKRCKHFELGGDKKRKGQVIQF", "length": 106 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P97876-1", "protein_name": "Basic leucine zipper transcriptional factor ATF-like 3", "gene_name": "Batf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQGPPAGGVLQSSVAAPGNQPQSPKDDDRKVRRREKNRVAAQRSRKKQTQKSDKLHEEHESLEQENSVLRREIAKLKEELRHLTEALKEHEKMCPLLLCPMNFVQLRPDPVASWSAHDAPDHPSFIWLGTLV", "length": 133 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q00729-1", "protein_name": "Histone H2B type 1-A", "gene_name": "H2bc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPEVSAKGTTISKKGFKKAVTKTQKKEGRKRKRCRKESYSIYIYKVLKQVHPDTGISSKAMSIMNSFVTDIFERIAGEASRLAHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSSK", "length": 127 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01534-1", "protein_name": "Testis-specific Y-encoded protein 1", "gene_name": "TSPY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPEGSLTYRVPERLRQGFCGVGRAAQALVCASAKEGTAFRMEAVQEGAAGVESEQAALGEEAVLLLDDIMAEVEVVAEEEGLVERREEAQRAQQAVPGPGPMTPESAPEELLAVQVELEPVNAQARKAFSRQREKMERRRKPHLDRRGAVIQSVPGFWANVIANHPQMSALITDEDEDMLSYMVSLEVGEEKHPVHLCKIMLFFRSNPYFQNKVITKEYLVNITEYRASHSTPIEWYPDYEVEAYRRRHHNSSLNFFNWFSDHNFAGSNKIAEILCKDLWRNPLQYYKRMKPPEEGTETSGDSQLLS", "length": 308 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03764-1", "protein_name": "Ethanolamine kinase", "gene_name": "EKI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MYTNYSLTSSDAMPRTYLVGTASPEMSKKKRQSANCDKPTRRVIHIIDTNEHSEVDLKNELPITCTNEDGEMTSSSWTSQTANDFLKLAYVNAKLDPSLPSQYFKQDIINVLQSLEIPGWSVPGSKESSLNKNLLTLTQIKGALTNVIYKIHYPNLPPLLMRIFGDSIDSVIDREYELKVIARLSFYDLGPKLEGFFENGRFEKYIEGSRTSTQADFIDRDTSIKIAKKLKELHCTVPLTHKEITDQPSCWTTFDQWIKLIDSHKEWVSNNVNISENLRCSSWNFFLKSFKNYKRWLYNDSAFTSKLLREDDKDSMINSGLKMVFCHNDLQHGNLLFKSKGKDDISVGDLTIIDFEYAGPNPVVFDLSNHLNEWMQDYNDVQSFKSHIDKYPKEEDILVFAQSYINHMNENHVKIASQEVRILYNLIIEWRPCTQLFWCLWALLQSGRLPQRPLIEGEKLMSEKAGLGDETHLMEHKNKENGKYDCSEDDSFNYLGFCKEKMSVFWGDLITLGVIDKDCPDIGKTDYLDTKLIF", "length": 534 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04902-1", "protein_name": "Probable glutathione-independent glyoxalase SNO4", "gene_name": "SNO4", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTPKRALISLTSYHGPFYKDGAKTGVFVVEILRSFDTFEKHGFEVDFVSETGGFGWDEHYLPKSFIGGEDKMNFETKNSAFNKALARIKTANEVNASDYKIFFASAGHGALFDYPKAKNLQDIASKIYANGGVIAAICHGPLLFDGLIDIKTTRPLIEGKAITGFPLEGEIALGVDDILRSRKLTTVERVANKNRAKYLAPIHPWDDYSITDGKLVTGVNANSSYSTTIRAINALYS", "length": 237 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0D2J5-1", "protein_name": "Zinc finger protein 763", "gene_name": "ZNF763", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPVACEDVAVNFTQEEWALLDISQRKLYREVMLETFRNLTSIGKKWKDQNIEYEYQNPRRNFRSLIEGNVNEIKEDSHCGETFTQVPDDRLNFQEKKASPEAKSCDNFVCGEVGIGNSSFNMNIRGDIGHKAYEYQDYAPKPYKCQQPKKAFRYHPSFRTQERNHTGEKPYACKECGKTFISHSGIRRRMVMHSGDGPYKCKFCGKAVHCLRLYLIHERTHTGEKPYECKQCVKSFSYSATHRIHERTHTGEKPYECQQCGKAFHSSSSFQAHKRTHTGGKPYECKQCGKSFSWCHSFQIHERTHTGEKPCECSKCNKAFRSYRSYLRHKRSHTGEKPYQCKECRKAFTYPSSLRRHERTHSAKKPYECKQCGKALSYKFSNTPKNALWRKTL", "length": 394 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0WX57-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 24", "gene_name": "USP17L30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGHKQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPECLDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSITSVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHPEQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYG5-1", "protein_name": "Elongation factor 2a.1", "gene_name": "eef2a.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENFNVDQIRATMDKKSNIRNMSVIGAFDHGKSTLTDWLVSEAGIVSSARAGETRFMDTRRDEQERCITIKSTAISIFYELAEKDLAFIKECKDGSGFLLNLIDSPGHVDFSSEVTAALRITDGALLVVDCVSGVCLQTETVLRQAIGERIKPVLMINKMDRALLELQLVPEELYQIFQRIVEKVNVTISTYAEDEKGPMGNVMIDPVIGNLAFGSGLHGWAFTLKQFAELYVKKFAGKAQLGPEEYIKKVEDMIKRLWGDSYFDSTTGKFSESATSPDGKKLPRTFVHLVLDPIFKVFDAIMNFKKEETVKLIEKMGIKLDVEDKEKEGKILLKAVMRCWLPAGEALLQMITIHLPSPVTAQIYRCELLYEGPGDDEAAMGIKNCDPKAPLMMYISKMIPTSDKGCFYAFGRVFSGCVSTGLNVRIMGPNFTPGKKDDLYLKPIQRTVLMMGRYVEPIEDVPCGNIVGLLGVDQFLVKTGTITTFTKAYNMRVMKFSVSPVVRVSVEVMDPADLPKLVEGLKHLAKSDPMLQCIIEDTGEHIIAGAGELHLEICLKDLEEDHACIPLKKSDPFASYRETVSDGSKQLCLAKTPNKHSRLFMKACPLADGLAEDIDKGRVTASQEMNARAQYLAENYKWEVTEARKIWCFGPEGTGPNILVDLTKRVQYLNEIKDSVIAGFQWATREGVLCAENMRGIRFDIHDATLTSTAIHRGPGQIIVATRRVLYGCQLTAEPRLSEPIYLVEMQCPESVIGNVYGELVRRRGVVFSESQVMGTPVYLLKAYLPVSESFGFTADLCANTSGQAFSQCVFDHWQILPGDPMDPTSKVAHIMADIRKSKGLDEAIPALHCYLD", "length": 854 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1PEY5-1", "protein_name": "Probable 3-hydroxyisobutyryl-CoA hydrolase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASHSQVLVEEKSSVRILTFNRPKQLNALSFHMVSRLLQLFLAYEEDPSVKLVVLKGQGRAFSAGGDIPPIVRDILQGKLIRGAHYFKVGYTLNYVLSTYRKPQVSILNGIVMGGGAGLSTNGRFRIATENTVFAMPETALGLFPDVGASYFLSRLPGFFGEYVGLTGARLDGAEMLACGLATHFVPSISLTALEAELYKVGSSNQTFISTILDAYAEYPHLNQHSSYHRLDVIDRCFSKRTVEEIFSALEREVTQKPNDWLLATIQALEKASPSCLKISLRSIREGRLQGVGQCLIREYRMVCHVMKGDISKDFVEGCRAVLIDKDRNPKWQPRRLEDVTDSMVDQYFERVEDEEGWEDLKFPPRNNLPALAIAAKL", "length": 378 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1ZXA5-1", "protein_name": "ADP-ribosylation factor-like protein DDB_G0292332", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDFIISFIKNLFGFLTIKKVMILGVENVGKTTLLYNIYKFYSENITTTTLSSLPIPIPTNGFNVESIVIEQVKFDIWDIGGKETNRICYRHYLTSEIDSIIFVFDSSDINSLEESKKEYQYLKNQISLKNVPFLLVANKQDLKQQTIEIDEILKTYFDKSSINETILMSQNNNDDLIKCINWIFSN", "length": 186 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q1ZXJ4-1", "protein_name": "Acetyl-coenzyme A transporter 1", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLFTLLKRHFGNELNNIVWLVLLYLIQGIPIGLSFGTIPFLLHKHATYTQIGIFTISTYPYSLKLLWSPIVDSYFVQSFGRRKSWIVPIQILAGIVFITISFFIETLLEHAETKIIYITIVFFLLIFLMATQDIAVDAWALTILSKPYLHYASTCQTIGLNTGYFLSYTIFLTLSSPKFANKFLRSVPSEEGIITLPGYLQFWGILFIILSIYLAFFKDEESTTITTTTTRHDNYNNNNNDDKNKQVKSKIENESIESKSMRSSPSSLSPSLLSSPVKKQNKKNKQHISIDKKDITIIKENNENNEIIDNNNSNNNYDNGKKSIVQETYGMDISESDLTPKQVYYLLWKIITLPHIKILSILFIISKIVFQPNESALNLKLLEKGLRKEDIASFSLIQFPSIIIFSIISSKWVKNKPLTIWSNAYLVGVFFILVNMCSVFYFPNLNGGEISWSHFFLLLMISLFSSFSYNLMSVSQGSFFLKISDKSIGGTYVTLLNTIANFAGTYPKLFILMLIDKLTTSECIVNISNDNSSSSSSSSSLISTSSNNLTTTTTIIQEQQQQVIIHDNISKELCAEQNGKYRIERDGYYLVATGAIIYGVFIYFVLKRYLTPIEKLKL", "length": 618 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q23888-1", "protein_name": "Large ribosomal subunit protein uL2m", "gene_name": "mrpl2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVLNWRGVKSRLYSGKRRIDGRNKGLIAIRSRGGALKRKYRYIEHYKQKWMDKWLFVMRIEYDPNRSAHIALCSILKEGIYFYVISIAKLEVGSLIITSALKLGTLQVGNTTKIKNIPEGLLINNIELIENSGSKISRAAGTSSLIIKKYNKKYSLVKLSSKECRLISNECYATIGTVSNIERKLKQNKKASYSRKRGIRPIVRGLAMNPVDHPHGGRTKGGVHWKSFSGKLAYNVSSRKKTKMTSRYIIIGHRKQKIMDKQIKNG", "length": 266 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q24113-1", "protein_name": "Protein no-on-transient A", "gene_name": "nonA-l", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEGAVKKNSLNSSPLPQRQQRGNSTNKNLGKPTPPKLNAASDGNPAEKKARLGGNTQNGGGVAGGGGTGGGGGGGGATGGVEFSRNRNRGGNQNENRQGFQVANNSHQKQINESPKPAAGNVPAKNNELSAGGGGQNQPNHSNKGQGNQGDQGEQGNQGPNFRGRGGGPNQPNQNANQEQSNGYPGNQGDNKGGQGQRGAGGGKHQRGNRSRRSGGSGIMNSSMGGGGQRGEDFFIAQRLLDISGPTHELPPIELPTDNKFVGRNRLYVGNLTSDTTDDDLREMFKPYGEIGDIFSNPEKNFTFLRLDYYQNAEKAKRALDGSLRKGRVLRVRFAPNAIVRVTNLNQFVSNELLHQSFEIFGPIERAVICVDDRGKHTGEGIVEFAKKSSASACLRLCNEKCFFLTASLRPCLVEPMEVNNDNDGLPDKTLNKKSLEFRHERSVGPRFACLNSFEHEYGSRWKQLHDLFKSKQDSLKRELKMEEDKLEAQMEYARYEQETELLRQELKKRELDNERMKLEWEMREKQAEEIRKREEEYMHRYQNQLLRHEEDMRARQQENDLLMQAKKLNMILDQQEGFGGSNSGFEHFDSPFEVFGNNSNNSTMAGPGGPDNSDGNQHGHIDSWGHRRF", "length": 630 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q2PRK7-1", "protein_name": "Odorant receptor 106-10", "gene_name": "or80a10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANETFVKNVDSFIITGFDHLQNQKLLGSLILISYMFILLGNGINLCIISTDRHLHKPMYILICNLAVVDIMYSSTCSTTMISVLLAEIKTVSYYSCISRTYFFNLGDLTECMALTLMAIDRLIAINLPLRYHSFVTNSRILWLIFLTWIFSFAVIGFLTYVADTLPYCQPIIKYVFCSYSSLVRAACVDPEPYFAISTVYSMVTLCGLFPFILCTYAVLAYSVTKLANSSRKQMINTCLSHIIVLFSFYLPKIVYILLTRIGLVLTLTERNAVLIVSCFVSLLVNPTVYCIRTKGIRKRITDIFLYTQKITK", "length": 313 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2YDJ5-1", "protein_name": "Uncharacterized protein CXorf66 homolog", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MNLFIYVLLLSIWTSSCLDRNESNGSATAVTTHAEFKQTKLQELRRRLLIIVIGTLITGYMVSCTCLLHYSCDSEEAHTAAKDKKEDITIKASRSSKISFTDSKSPTAGLGDPERQSVVSRIDKSSGPSSPRKVPSSAEKLVRPSSQKKPSKPSAPKKVLGSPPQEKLHRTRSPKKAHRQAHAHKPVSQVSPSYPEKAIKSTWPPSLQCRAKPTKTPLPYPKNQSFPEQSSVDKLTKRQRYLKLKCPASAGRAEILSRPHPVKFCRCYKEKCLVCRAVSEPFITHVSDANKKHVPVPLFSRELKHFYKSYKKKQPKYNTLYGNMSDSDITTYNSDGESDREVIIMCNIKCKEDIYKNSRNN", "length": 361 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3L180-1", "protein_name": "Alpha-defensin 26", "gene_name": "Defa26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALFLLAFQVQADPIQNTDEETNTEVQPQEEDQAVSVSFGNPEGSDLQEESLRDLGCYCRKRGCTRRERINGTCRKGHLMYTLCCL", "length": 93 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TR54-1", "protein_name": "Gasdermin-C4", "gene_name": "Gsdmc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGYSFDRASKDVVKKLQGRDLRPVECLSDATKFRLFHILQETPRSGWETEDIPVGFTLLDLLEPNFPVPEPEVSAPKPFIHVQSTDLEANLNVADIARGGVGYVGYGGYNIEVQSTSIPNPKLEILQNRKLLDKLPTFMKFCRMERKNLYVVTEAYEVSKDTMLTGLSSVNLLVKGFFKQLFKVRGKAGRSEKYSIPIPKGSVLAYKKQQLVIENNTCVILPSATKKKMTFPDRPLKLYDLPVTLRYQEEVIETGSWIDDIDPIGTIEEPANLNFMCLQHEVSEQTQLLAELSKDVQEVVFSSFLHMLSDRDVLYDLMKMLELNQLGHMDGPGGKILDELRKDSSTPHDVLKDLNLYLLQALLVLSDTQLCLLAQSVKMGLLPHQVELVKSILQTNFKYSSNTPFTLQPQLLAPLQGEGLAITYELLEECGLKMELNNPRSTWDLEAKMPLSALYGSLSFLQQLQKANSSSKPSLSPGYI", "length": 480 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3U0I6-1", "protein_name": "Endoregulin", "gene_name": "Erln", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQMVPPRSIQNEDFWKNPWDVGGLTVIGLFTSTFLLFVLFAVVFGYVEKAVFEEE", "length": 56 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3URS2-1", "protein_name": "Zinc finger and SCAN domain containing protein 4F", "gene_name": "Zscan4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIMQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSEKDPREVPGLQSRQEQLISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3ZCQ0-1", "protein_name": "Required for drug-induced death protein 1", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVGARLRSKASSLVGRGPLGRLRRAGDEETDAIVEHLEGEDEDPESQDCEREEDGRRAGTPSARRVHLAALPERYDSLEEPAPGDKPKKRYRRKLKKYGKNVGKAISKGCRYIVIGLQGFAAAYSAPFGVATSVVSFVR", "length": 140 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI3-1", "protein_name": "Defensin alpha 3", "gene_name": "Defa3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTLTLLTTLLLLALHTQAESPQGCTEDQKLLIMEDQDISISFTGDKGTALQDADVKSGVICNCRPRGCSFKERVYGECGYNGHILRLCCQPLNTMNKKSPSVI", "length": 104 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4JEI6-1", "protein_name": "Defensin alpha 8", "gene_name": "Defa8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTLVLLSALVLLAFQVQADHIQEAEEETKTEEQPADEDQDMSVSFEGPEASALQNLEIGWPLKQCHCRKFCRPYEKAEGSCRPGLFIKRKICCIQQWTPGRT", "length": 103 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KL71-1", "protein_name": "Small proline-rich protein 2A3", "gene_name": "Sprr2a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q504N7-1", "protein_name": "Pyrin and HIN domain-containing protein 1-like", "gene_name": "Ifi214", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVNEYKRIVLLTGLMGINDHDFRMVKSLLSKELKLNKMQDEYDRVKIADLMEDKFPKDAGVVQLIKLYKQIPGLGDIANKLKNEKAKAKRKGKGKRKTAAKRQRQEEPSTSQPMSTTNEDAEPESGRSTPDTQVAQLSLPTASRRNQAIQISPTIASSSGQTSSRSSETLQSIIQSPETPTRSSSRILDPPVSLGTAYSSAQALGVLLATPAKRQRLKNVPKEPSEENGYQQGSKKVMVLKVTEPFAYDMKGEKMFHATVATETEFFRVKVFDIVLKEKFIPNKVLTISNYVGCNGFINIYSASSVSEVNDGEPMNIPLSLRKSANRTPKINYLCSKRRGIFVNGVFTVCKKEERGYYICYEIGDDTGMMEVEVYGRLTNIACNPGDKLRLML", "length": 393 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q54B59-1", "protein_name": "O-methyltransferase 12", "gene_name": "omt12", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDWDKTMDLLFGFVTGHIHSRMFETILKFSICDLLEDGPKHYSEISKIIGFKNESYCYRLMRYFVPYKLFNESVVQVGLFSKTPSSTQFSKNGTLKNLGRFHCQDHHYRIFESLPKTLEMGKNQGPSSIGLSSFWEHFETDESYKQLFHNAMKDYTSLIIDRLISKISLSPNFKTVVDIGGSHGFLIGKLLESNPNIHGINFDLENIINSSTSKNENFQHPRLKHVSGDFFNSVPEADCYILKYILHDWSDEKCITILNNIHKSLKPNGKLFINDLVLDPSNYTKEAVFKDILMMQYFDAKERSINEWHQLFEKCGFKIDSVDTSISPQLMIVSKINSSNINLNDCTNFNSEIVEEKLKNSLPQFVNC", "length": 369 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B60-1", "protein_name": "Probable inactive O-methyltransferase 11", "gene_name": "omt11", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MECSESLELVDKFACGHILSRMFNVVMKHSICDLLEDGPKHYSEISKIIGFKDDSYCYRLMRYFVPRKLFKESVVQVGVFSKTPFSTEFSNNGTLKKLAKFHCNSFHYKLSQVLPETLEIGENQGPSSIGLSDYWEQIEKNEIYKNEFNDGMIGYTTHILKFLKGKIDLSKFETVVDIGGSHGYLIGSLLDRYPNVNGINFDTDMVINSSNEKYQHPRLKHVAGDFFKSVPEADCYLMKLILRCFSDEKCCELLKIISKSMKSNAKIIILDIILDSSKYLNFDTYLDILMMETLDGKQRSLSEWIKLFEMSGFKIDKYESGSPNYLIISKE", "length": 331 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54B86-1", "protein_name": "Hly-III related family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPRLDHKKNKEEKDNEPLMMVNNYNIGIQTDNNQEDIQNDYHHFNDLSINIKNNKNNNNNNNKCNSLHHKHYHNRFIINGGNNNNDNNNNNNGDDCCANIELFVDLMLSENEYILSGFRLHTKNSYMECTKSIFKLHNDTLNIWSHLLGALFYLVLFFTSIIKIIKLNNNDGGGGGGIGNNFILNSDEIKLLETIDLPSNFNYLFFQLSCFICFLSSTIYHTYRSHSIVVFKTTLMLDVASIALLILSSVCLIIDSELSCWPYFKRIYLFSFLILILISFLSLPKIMREKRYGLRTFLFAILALQGLVGHLFKIYLQGYFDKDPNQFYNLIGAYTLFGLALSIRRFKVPESFKPGHFDVWVNITFNIVYNII", "length": 372 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54BG8-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGKIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54C66-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKTKKYKNPFPTNSYKEPENDSDNEYILHNEEDNEDYGSNNNNINNDGFSYEDNIENSDTEDEREDYGYINYNTNNEEDDEPIDLSTPIKKKKANNKSFKPPYKNTTTTTTTTTTTPPTPPPSKSNNNNNNNNNNNNNNNNNKNKENINKESEYELNKFLDLYNDFKSESDNKVKPTATTTTTTTTTTSTSTSKLNKDKKGVIVIESDEEKEDNTIKINKRNGKRKEGEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQGNEDNLKSENFNKFKKLKSFSNQPTPLPPMLSNPFLNNSGNSHNNNNNRILFNSQFTNASNLNNNINNNINNNINNNINNNINNNINNRNNNTNNYTNNNNNNNNNNNNTNNNNSNNNINNNNYNNNNNNSFSFLPIRSNTLPTIVTRRTGIQSSSSDNGNSNSNHSSSMNKRNTSKSNNKKSTTTTKTVLPPPLSSRTQEEEDYALALSISEGLNGGSGGGSGSGSGSSDNSTKTKRSKSENDLPNEETRHQVEMDRRFAEQLHREQHENINQIQQLQRRLHLNQQRTNNINRNHHGDEDEEDIEMLNLRAYQQIQQQFNQHFNQQLNQLANHPLANLFSHASRGRGRGARRIPHHPHHHHHPHQAQYLTGLSQEQLNLMTRDFSSNDYELLLQLDENINNKGATTSDIENLPVHTLNKPTATTTSTTTTTNSSTSDDNKKNEPTTDVTCCICLCEMEPGDAVRTLPCKHFFHVSCIDQWLKVNKVCPIDKKAIDEK", "length": 766 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54CY8-1", "protein_name": "Obg-like ATPase homolog", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKGIKLFNNFTNTKQILFFRSFSTAAKGDRLKASHYVKTRGSCKSISIVGLPNIGKSTFFNALTSSNAAMAANFPFCTIDPNIGKVFVPDERLDYISDLLKTKSKIGVQLEFVDVAGLIKGAADGEGLGNKFLGNIRQTSLICHLVRCFEDKGITHVSDEIDPIRDIETIETELILADLQSLEKMLTEGKKKQSNPELQMKFDLVKRISEYLHKGLPARDVEITDMEWPVFHSLHLLTSKPTIYTCNVAEGDAATGNKYTDLVKEYSKSKGLEIEPVVISAKIESELANMEGNDETKKEFLQLYGLENNGLSKVINGAYKLLGLQSYYTASSNECHAWTFKAGWTAPKAAGVIHSDFEKGFIKCDTISYNDFIECKGDEKIAKEKGKQRSEGKAYIVNDGDILFFKFN", "length": 409 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54D44-1", "protein_name": "Probable polyketide synthase 42", "gene_name": "pks42", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIESQREFNCIGGDNQNGVAVIGVGFKIPLDLENCLSSPSELYSALFNEFDSVTKNTSSRWSDNYFKNGDIVSLSAGLLPLREIKSFDPTFFGINPSDADLIDPQQRLLLKCVWNALEDGGIDPISIRSSDTSVYIGCSTIDYFLLNRNPVDPHNHGIQTASYSIPNRISYCFDFRGESLFVDTACSSSLNAVHLGYNSIINLKSKLSIVGGSNLILDPQNSIFFSKQQVNGPSGKCNSFSEEADGFVRSETVGVVVLKNLKDAIKDGDRIYCVIQGSNSNVDGNYEKLNYISPSKLSQAENITKALKSTNGAVNASDIDYFECHGTGTPTGDPIELEGISIALNRTQQSTTLSNPLLIGSIKSNIGHGEASSGIASLIKCCVMFKYRQFLPNINFKTPNPLIKFKEWNLKVVTEPVPFNNNKQTIMAINNFGVSGSNCCIILSEYKSNNNNNNDFKATTHLKSKKFIIPFSSNSSTSLDNYKSLLSNETNNFQDFVIKQINNKSTSLIQRSVIIASNWSEFNESSNEIQSNIKKSIISNITIKKKNAVTVFVFCGQGSQYNKMALSLYENEHIFKSTMDKLDKELSKHYGYSILEKLRSITDEDLVTIHQPILAIPVNVMVQVSLYELYKHWGIKSDIMVGHSFGEIACSYCSGMVDFKTLCYLTYHRSVAQNKTIGSGKMLSINIGAKEYLDSYSTKYPSVEIACYNSETSIVIAGNEELLNEISKDLKSKDIFTAMLPSLSAFHTTHQSVIKDDICSLNFKSTLSKITVFSTVTSNQFGINNNNNNNNNQLNSNYLFQNVIQPVKFSETISNIYKYIESNDMGNEITFIEIAPHPTLQYYLNQMKSQQSEYFNNGEKISIYSACNKKKNDYNEFLKTISTLFVNGYNNINFKSQIINNNNNDNNNNFNLPLYQWDDNEYYKIHPTWKKANKNGPSINHLGNLNDSSIKSFKTYINTRKPQFQWLKGHSLKGKVVFPGMGYISNLLSVYNMNQDITINEIQFKSAFILVDGVNNCLETSIVPLTKNEFNIKFHFKDLKTNKWVLCANANYSLFKHNDNNDKLDIEKLKSNCNYTIISKDELYNNIRAKSGLIYKGLFQGVKEAFIGNRCSLTVLSLNEIENQQEFKHLLENRNFNSLFNTAILDSCLHGSLHSKEQSQIYFDKCEGFKYYSNNINLATSKRNEYKEINVYIETNPVINSTVIVSLKIMLPDGTLLIEIQKVVCKSSIPIIDSTSVIQPSPKDLHTPYYQPKNSLIKPPQSFKHLHCMKEFASIESDNREMVYMSIYHLIFKAINARSPTKINLESLENLTLDQFKELIKDSAANIQRSNQFIYECLKLYHTNHSNYKKNQIKDFIKECEDFNGYNQIIFKTIKIYAKSLFPLPDDDPFTDTIQSLFEDDQLENVYIHLKHLYPVNNLLSEIVFQSIKPIINQTSTFRILEIGAGYGTISQLIFDKLEQLLADNFTSSRIDIEYTFTDISNTFLPRAKERYSKYKRFNIIYKLLDLELPLTEGIQDFRPLYYDIVVMSNVLHVVKDINFSTNEIYKVLKQNGQLIFVEPTYKNLYLDTIFGIFPQWWSFNDDIRTDRCCLEPSKWFEFLETINFKDTIILGQDNKEILKNVENSIILVQTRKPSQLELSINNSPSTNQFKSFENIILYTDDNQQPNDCSEIIDLLKSLELPIKIINNIDQFNQIIKTQYNNNNNNNNNNNNNNNNNNNNTNNNLIIFLKSVNQLNTNNYKDITFEYVQINQILVKLELEENYKLLLITNNSQSSNYLSNSLIGTSRYLFADIVSSKLDIITIDFDTVSIKNHQNVISVINHLLDSKDNSEREYYIINNEINIERYKNESNIKHQLKSKTFQENKDELMVQLDSNLEYRLKSKSKQELKSTHVEIQVKAIGINYKDYATYSGLIDSIIEIDKDKEKDENYDQNYPSIGNDFSGVITRIGSDVRKFKVGDEVCGLAPKTSASHIITEEGYLCKKPSNISHSEAASSVTVYTTSFQSIYSIGDLKKNETILIHSGSGGIGLSALEILKWKNHQGYIFATVGSEDKVKYLTDTYGSFITGIYSSRDKDYQDQIKEKLKSLGCDIDHQGVDLILNTLSVEYMDSNFKCLNQKGRCIDLSITHLTPFDYMDYNKFKFNVSYGNIELVVLPSKIIKDHLKKMLKAFSLGSLRFIPIVEFSNLNIRNAVEYINQRKHIGKIVVKNDVDFINKLFIEQQQQQNSVENNEILMKDKYDISNLELGKNILLTGQTGIILTILKWLYKHSNNSIENIIIISKSKLKWELELFINESTNNRIKIHYKQADVGNNNELNQCFEELRLRHSIEDINSIFHFAFINDIGQFEDVNMNRMDIAHHAKAIGSLNLHNQSIERKWNIKQFVLASSALSVFGGDNQCCYISACSVLDSLSKYRKSIGLPSLSINFGGVTSTGFVSRSGAVEANLESSIINLITPQSLISSLDLFIQNSQTFSNYTHFNFIYDNIESYSLNRMLFKFDYLINQHSSLVSNKRLGGINENNNIGDLLVSKIGELLSIEPSKLNLDFRLVDYGLDSLVIVQLKNFIDKQFQPHLISILQLQNNKISTTIEIIIKGYNNNQNKKIKNEQSNDIPSVVQKETIKDNNENKDDIKIDMDDKKENLKGKKENIDDKKENNN", "length": 2655 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54E06-1", "protein_name": "Transmembrane protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTIINNDNISLATSAKLSQFIVSGDYKGPFTIIGLKTKILSFSLVIEFILLKIELIKERKDGLKINFDDSISGSCNYELNYTKQDTLFQRFQSKFKIEHTINPENGETINTGITLKKLFIISIPMSILFVALNWIWMLAISMTEVSISTALYLKILKTISVIIFMGGIVGIAITTVGTSKGEYPHAIKGEILMIISAAMWGLYEVLTSKFIGDANRTIVHTYMGLIAFVNLILGIPVIVILNVTNFEPFSVPSISVFGMLLLNAFVGFSVNYLINWGLSVTSPLFVRSGELMVIVATLLFDIIIKHMKLPLLALPGYSLIVIGFILSVYIESRDIKQQQEKEKEKQKNNNGETESLLNY", "length": 359 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EC9-1", "protein_name": "DUF781 family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLNKIILIFFLINNIFSIVVSSTKLNPWVFEERIKLYDILINSTKVEIFGDDNLNNCFQGFKIQLEWQKTTGRSMIIDNSNISVNSWWGSMNYYESIIPFISAMNLGIIQPPIELVNIGDDRFCTDYSECDKELMEPWDLYFQFLIKIKDEKYSYSIQQQILKYNWDGHMKSLSIGLKLFNDKLNYLSKNEIKFSTGFVHFVDIISLINFNTNYSQILPIFDSLPPRMLTNSDHPPFFKGFTRTQNFYTVSVLSINELHENQILWNYFLNLLKTKTENEKCRDFINQEIINFTKYPESTLVKLLLKLLLNNC", "length": 312 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED6-1", "protein_name": "Probable polyketide synthase 41", "gene_name": "pks41", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDSKNLVDENCNKVAIIGIGFRFPNLKGDITPNELWSKLLNRYDGIVKNDRWNESFFKSGDISTNYAGFIPFEELKSFDPLFFGINPSEGIHMCPQQRLLLKCTWEALEDSGIDPIEIRGSNTSVFIGCSGADYQNLNKNDNKVQQEIFSSSTHSISNRVSYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNISKSYSRLNILSKDGKCKSFDAGADGYVRSDAAGIAILKNLNDAIKDDNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGQVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSDNPLLIGSFKPNIGHTESASGISSLIKCCLILKNQCFVPNLNFNKPNPLIKFDQWNLKVVTDPIDFSTLNYINKRVSIAINNFGVTGSNCCLIVSSFKGNQIRNNINNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVVIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNVTMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLNEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKKDGVFCAILGSPTSFHTSSQLSVKDEILKISFKSKQPTIPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEVIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSDHNNTNNQTRVNLPLYQWEDQEYWKLDNLHQYHLSNGPSINHLGISNSNHTPIKSYQTHINIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGESKTDTNPNKELPDILISFIEFKTPLIFMDGISQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGPNLNEDDEQSLFMYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVDKCYLGYNCSLSEISIIQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEELTYYSSKVPKTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDPLAMEYPTNEIYSCNLQSKDSLIPSLSSFDHIFKRKIPNEYVDQINIYESFIPKLLFSNINKRCPEITIDEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRFNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIIGDGIFGVFDQWWSFQDTEIRKDRCCMKQKTWYKLLKSVNFNDDIRMTPELTCFVIQAQKPSISNLSFSKSETTNYDSIIVFGNKYASNLSNHFIKSIDNGNLQFISTIEELNKIGKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNCKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITRISTGSKEFKVGDHVYGIGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITHYSIEKVKESIEFINERVHMGKIIINHENQDSIINELIEKQKSINKFDQSIFKQNYKLEPSLLGRNILLTGQSGIVLEILKWILRNSENNSIGNIIILSKSSIKWEMEYLINKVKLINKLGNFFNNIKFHFKSVDISDSGLIDESINKLLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKLKNFIMSSSVSSKTSTANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIESTGFVSRNESVAALLSGEGFIPISANLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISEILSTDILKLNKDIILVDYGIDSLVIIQLKNWVDKEFSIPNELTIQKIQNSTINSFIQLVKNSMDKNKK", "length": 2542 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ED7-1", "protein_name": "Probable polyketide synthase 40", "gene_name": "pks40", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDYKNKYQSNENCNKVAIIGIGFRFPNLKGDLTPNGLWSQLLNKYDGIVKNDRWNESFYKTGDIPTKYAGLIPFEELKSFDPLFFGINPSEVIHMCPQQRILLKCTWEALEDSGIDPIEIRDSNTSVFLGCSNFDYQNLNKNNNKIQQNIFASSSHSVSNRISYCFDLHGESMTIDTACSSSSNAIRRGYKSIIDGSSNISVVGGINILLDPNTSKSYSQLNMLGKDGKCKTFDADADGYVRSESAGIAILKNLNDAIKDGNNIYCVIDGSASNVDGNGFSDKSNFYSPSKSSQVECIRLALESTNGGVNENDIVYFEAHGTGTPTGDPIELESVSIALKTSENRSSNNPLLIGSFKPNIGHSECASGISSLIKCCLILKNQCFVPNINYNKPNPNIKFNQWNLKVVTDPIDFSTLKLSNKPISIAINNFGVTGSNCCLIVSSFKGNQTNNNNNKSKSPKQYLIPFSTNSIKSLDLYKSRIDNNVEFKEFAENQIKSKSKKLIQRSVAIASNWDEFNLKSNTINTSNDKLTSNMLVSSNKKNATMVFVFCGQGAQYSTMAKNLYDNEPIFKKSMDKIDSKLSEYYGFSILEKLRSFNENDLKGIQYSIIAQPSTCMVQISLFELYCHWGIKPSIIVGHSLGEISSSYCSGMIDLDTFCYLIYHRSMVQSKTNGLGRMLSISIGENEYNSKYSSRYPELEIACYNSPSSIVIAGKELILNEIIKELKQDGVFCTILGSPTSFHTSSQIPVKDEILKISFKSKQSTYPIFSTVTTNLYDEMNPFDTKYVYDNIINPVRFTNTISNIYKHIELNYSVNNNSNEIIFIEIAPHPTLSFYLKQMVPEDKKQSVSIFSPLSKKKSNDLFEIQKLISELYCLGYNGIGFNIQLSNLNENDNIQTSLSLPLYQWEEQEYWKLDSLYQHHLSNGPSINHLGISNSNHTPYIKSYQTHIDIQKKPFQWLKGHQIKGKYYFPGCGYIDNILKIFGDNSESTTNPNKELPDILISFIEFKTPLIFMDGVNQCLQTNIHSTGKKEYKALFHFKDEKSSSDWVQTSTANFQLFSRGQGLNEDDEESLFKYNINDLISNQCNLTKLSKQELYSHIKTKCGLNYSGDFQRVEKCYFGNNCSLSELSLSQGVNENRSTFFDSSIIDCCLHGSIGLIDENCQLVFEKLEGLTYYSSKVPTTTSQHSKIYVYSKLKPRIGDSYSASIIVMLENGTVLFEMENASFKSTTKIKDSLAMEYPTNEIYSCYLQSKDSLIPSLSSFDHIFKRKITDEYVDQIKIYESFIPKLLFSNINKRCPEITIAEIQSSEIEQLLLKYYKIKEDNDNKWLSRLFTFAFESIKQWYHNEDYDFENVLSPHNFKIFSKSTKIISKLLFPLENDNDEDSPQSLFEGGLLDKFYSSGFSAQNELVGEIIQESIKPILNEKLVFRILEFGGGVGSLSLLVLEKINSLLIQYPNYQIDIEYTWSDISPSFITEAKAKFEKFNDRVNIIYKALNLEQPLIGEKQGLKPQYFDYIIMFNVLHVIKDVKYGVEQIYQLLVPNGHLLFIEPIYKSIVGDGIFGVFDQWWSFQDTEIRKDRCCMNQQTWYKLLKSVNFNDDIKMTPELTCFVIQAQKPSISNLSFSKSETTNYNNIIVFGNKDDSNLSNNFIKSIDNGNLQFISTIEEFNKMTKYISNESIIYFIKSIDELSVDNFVNITHEYTQINQKLMELNSKCKHVLITNDSTTTNYLSSSLIGAARYYHECPLELFILNFDTPSIIENQNLFKTIEPLINSSINIQREFIINNHKVYYERIKNETKLKSIFKNSSSFESLEQVDNFMISLTPNLEYKVKVKPTSILKENEVEIKVMSTGLNYKDYLIYAGLVESVEPIFGIEFSGIITNIGSGNKEFKVGDSVYGTGKSTTSSHIITDIDVISHKPSNISHSEASSIPVVYLTSYHSLYNIGALKNNETILIHSATGGVGLSTLEILKWKGHSGLIFVTVGSNEKEEYLRENYGDMISGIYSTRNKNFVKQIKSKISKLNPFGKSGVDFILNTLSSSDYMDSNFKCLNMSGRIVDLSITHLNSNEFTDNKKFKYNYGYHNIELQYVDKKIIKSTLSIISNAVSSNDLQLIPITEYSIENVKDSIEFINERVHMGKIVVDHENQDSIINELIEKQKSIDKFDQSIFKQNYKLEPSLLGKNILITGQSGIVLEILKWILRNSENNSIDNIIILSKSSIKWEMELLINKTKLLNSNSINSMGNYLNKIKFHFKSVDISDSGLTDKGIHELLIENPDINNIDSIFHFAYTQATCNSDEVDLHHLTQSHSAKSMGAINLHNQSIKRNWKIINFIMSSSITSKTSSANQCGYISSNNVLDALSKYRISIGLPTICTNYGLIQSTGFVSRNESVAALLSGEGLLPISTNLILGTLDLQLQNQAQSSNLILSNFNFTSLNGLPQKSLISKFDYQININEENEKSKSLLKDDNVELTVDQLITFKISELLSTDILKLNKDIILVDYGVDSLVIIQLKNWVDKEFSIPNALTIQQVQNSTINSFIQLVKNSIDKKNKK", "length": 2552 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54EN3-1", "protein_name": "Alkyl transferase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNCSNNSENCNINDNKKKEENVKNQNSNKNSNNNNNKSNIESIILNKKSKFSSEKELDEKENKDLKDLSNNKPINIDEYEGLPRFENEQNARSKSSLWSKLCDWMYDQNFKIASSTLKNGPIPKHIGVIMDGNRRFAERNHLETKEGHKKGFNTMLDLCQWGLTLGVKIISVYAFSIENFKRSKSEVQDLMELANNKFTEMISKSHKLQQLGVRIRVVGDHSHIPEKTKSILAKAVKSTENNTKALLNICLSYTSHEEILHSMKILSKGVNQEKKIEIEDIDQDLFENCLYIKEDLDILIRTSGEYRLSDFMLWQSCFTNLALVNTLWPDFSFFHFIYIIFLYQFNSKTLKNEIQNQYKFNNNNNNNTDNNNNLKENIKNLKSDQRVKEFINHLKISEEKLFDEFISKYNEEEEEEEEI", "length": 420 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54F52-1", "protein_name": "Saposin B domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLIFIVCLLLIFNYFIGISFGNKQINSNQQQQIINTDKNYNHNKNNKIIVSHNKNNNNNNNYNEIETENLGCTFCKYLTEKVEEYLQANSTEKEIISYLDEECELLNSPNLVLTCQNLVQQYTPIVIELIDNNESPSVICENVNICPTSSSSSSSSSIEEEIIKKLNIDDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEEEEVNTCEICNLVSNLIEKYIKINNEVDEIRELIENECELLSNSKVSSCYSLVDQYFEHFYVTIENNYSANEICQLFQFCPIESSSSSSSSDIINNIPLQDSGCTVCTVLANYAYKVQANESIPEIIGSMDEICNKIGAWRDICNSIMRSGGQQLVEDIVNKGEGVYTACSNIGYCQSSSSATGTSGFSSGGSGTSTGGGYSTGDFYYKPLK", "length": 416 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54GT5-1", "protein_name": "Endoplasmic reticulum junction formation protein lunapark", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLFSKKNGFEKQLLDMETKILNLEDKLSNSRIFHQKVLHKIVLYSFAIEFFIILFTYVKSRSLESIPEKLFCCIYLVLFPIFILILTKVYGFVYKYLIKKNEVRLDSLKTGLQKKLDERKRETDYENTQKLLDRYEKNPPSPTNKPLGPPNLNNNNNNNNNNNNNNNNNNNNNNNNTLGNSMRNRNQPFNISSQQNQQQQRMIQPQQLSPQQLQLLQQQQRLSQQIVPSQQQQSQSQPQQQQPILNQPYNINNNNNNNKPPPPIQLPPQQSSQYIGNQQRLPPQQYQNEQKSKWWLDKLVDYLISDGPTHGSPLICSNCHSHNGYVPVEELSNIQFRCRVCKTFNQRDSVNNSTTNDDRNNSQNTGSNQQQSQSLQDQQPSIEEIDKNFSVTEQKNETNNENYSDSEKQLEENNNNNNIDNDSGSSSSQNTPNKKKGKGKGKGTPTKKTN", "length": 452 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H60-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MLDFFHLKDVDEFFRLLEKKNLQNLDNQIDGPGNLNWRTTYTEKDFSKVPKFRGIIHIVQIRDLGTKIHRDLLYEIMFEKLLDIARLNNESKLLKNEIQDLKTKLDEYHNNNSTTNTDLIINSFINVIDTTTTTTTTKTTMGATSIDKKQSEGDSIDKSIELDFFKIKSDQSQQSSPSHKLEEKQNQVNNITNEIPQESIKTVKQQTQTETNQQTFSSTSPSHQNEEKQDKQEEVKQEEVKQKEGIQKEDKKEEDKKEEGKQKYGEIFIIEIPQEEEKQKEEGKQQDGENFIIEIPQEEDKQKEDKKEEDKKEDKQEEDKQKEEKLEDKQKNGEEFIIEIPQNETLEIKVDTHPRSSNDDVSTAEMEVEALKTPLFAETTFVTKQQVITNKKLLVYKQSDFFPNMTTLLQSRLKDVTVQEVKDLTKIGLNDNSYSVGDFENVFVLYAVSCMGARTDSERDAFKIKSIRSIIGDKVPIIYGVFMIGKNGPTRIKVEHTQTSISITHSMSDIGRNLQNNENLKQLQSFLQQ", "length": 529 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54H72-1", "protein_name": "Tudor domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNIDFEDYEFYDDSDFEINTVDESVMTYSSVFDFLRFGKIPKFDTQTKMKHFKDNISKYRIESKDILHTNVDSKILRRLSEIPRVEKIFPDPNTLQLEVFKPNHELRNSNGELLSKHRPLQETLKLIEKQYYWECKFIHTSMEVDITKLYSFCDLCSQSSVSRDMDIDSNDEDKILEQMDIVEKSFSNDRNNNNNNDDNNKSIDEKDKMNICGIGIDLEAIKEGKLFEDELAEALGFPEYNSSVDNSFNSSVNNSNLNNSSLNNSLNNSKNNNNNDDDNNNNNNNNNDDNNNNNNNNNNNNNIISNIDNNNNNNNNNNNISNIDNSNNNNNNNNNNNNPVNDDFSFIIPKDYQSKNHLNDNENKDDEKDDDKDDDKDDDKDDKDDDKDDDKDDDKDDSKDNGYIKTNVSLSSSSSSDNERDDGDSHSDKSVDNDENNNNNINNIISDCNNNNNNNNNNNKINGRTFTSRRTRSDSNTSNSSVGSYISNSSKSSANSYDFSSSDQDYKSPNSPTVKKTRGASLVNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNSILKPKLKSKRASASTAINSFISQFITPKHPPKSSSRLKRANRSNDSSDSGDSSSNNSSRSSSDSSDNENNNSYYLPIQSRRSTSKQILKDHLKSPTKKPRRIIEEDFYHVEEKKSPTSKISTPISRSASYNFGRSSPGSSPGSSPSLSPYSSPPQSPPHVYNHNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNYNNNNNNNNNIRSILKSPQSPSISPIKTPRRSPQQQQQLQLQLQNYIPMPTKTKTPTKAPYVPNYALAPIEPKPTQKTPVHVFGGNQLSVKKRQTIEDMITEVLKMNVDTAALKLPLPKVGQHVEGKSNMEDYKDAWFKGVVKEVLPNDFFLISYIDGGEEELSYTRLKPNLTSELEPLKLEEIVVGGEYLGSYRNFYYNVYVLEILRHSIRVYFADLEMAKTIKYSQLYLLSSFVKR", "length": 998 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54HE0-1", "protein_name": "Conserved oligomeric Golgi complex subunit 5", "gene_name": "cog5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNNNNNNEGVSSSSSSSSSPLPNISSPNLISNSNIENDIEIKKKSNNNNNNIFEGDNSHIYNQFLGEDFNVVHYTSNALKVSSISLSLNTLTSCTRELGQELTENITTNYDDLFKLANNIKELDQLTDTLKLGVSNLEESIQRMKNDISEPYNKVKSHIGQLKRVQDSCELLRKLIRYIQLVKKLKNHLQAGSRDLSKSAQCINEINLLKKDSDLTGINIIDSQVVWIKTCSDQIITISSTLLYQGMENQNQTDVANSLQVFHNMTILNEKVYSIVNLTTEKVIKNIKALLNVNKLIADLPKTTITNNINNNNSNNNITTNNNNNNYNNNNNNNNNNNIISTSTDKSIWLKFESLIDTLYSSLIQILHLQRVLLKIKDPLTHKSLMEVLLIKQHQLQQQQQQQQQQQQQQQQQQQQQQQQQQQVGTTSNNTQPILIEMISTLFWKSILKVLENNLLVAAKSSNIIENTFIREYPKVSKFFLDFIKKLQNYIDIHQMDIQQQFMIVLSNINQIIGNNNSNNSNSNSNNSIESSLSTSSSSSSSSSSSSSTTTTATTSLILLSADDYKLSLFKSIGLFEKAYLEYSQSKMSTIVNGLFPQSTWSSRSTLPVIPNGKQLVDLSKTIWSEIEWLVGNNDRQLLGKLMLVVSKVIDLFSSKIESMVQPPGLIVLNSNIGSSSSTGGVNNNSNSNNNNEIITINENSKPTPSQTVNTLLFNVSIQLNSSIQSLLTSQPLERESIIVIEKSLNSLITICTNIITPLMNSFFTHIEQIFSTIHNEDWYNEKTTKMLINKSNQTCSSYMESFKTLVNYFQNQYLMRFTPCQLLNNQIKSMISKIFIVYLKYCSLLKQPFSENGKLKMVNDLTHLEFAVTPLLVSGGIKEIGESYNLIRNYKQSIFN", "length": 898 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54IX3-1", "protein_name": "Probable polyketide synthase 26", "gene_name": "pks26", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METNNNKNIQEDIAIIGFRIPGCQDNTPSELWNNLMNKFSGVGKTTERWSDNYHLSGDINNGNSGLLPLKEWKKFDPAFFGINPTMVSTIDPQQRILLKCTWEALEDAGIDPIKLRGSNTSIFIGCSTGDYLDMVKSNNEIQTNLFGSVNHSLSNRISYCFDFHGASMTIDSACSSSLNTVLLGCQSINQGKSNLCIAGGVNFILDTTIPTAFSFLNILSKNGKCMTYDEGADGFVRGEGAGLVVLKSLKDAIKDGNNIYCIIKGGNTNVDGNGNADKANFFQPSKQSQSDNIKLALESIKKKSMLDIDIDYVETHGTGTPTGDPIEVEGISKVFKENHSPENPLLIGSLKSNIGHMEAASGVTSLIKCCLMFKNKSFAPNVNFQKINPKIKLDEWNIKVVTEAIPFKKNKITSMVVNSFGVTGSNCCLVLTESINNNNNSNVDKITKNEKEYLIPFSANSNQSLKNYIEEVSKIDESLQFEDFVYKQLSNKSTSLFQRFVVTSKDWKELKYKLSQPLPLKEISSSISVKKPNPITVFVFCGQGSQFNKMGLELYNNDKNFRNYIDRFDKKLLEYYGYSVISKLRSIDDNDLITIHDPIIAQPATAILQISLFELYKHWGINPSFIVGHSLGELPMAFCSGMIDFDTVCYLLYHRSLAQSKTNGCGKMLSCNISSEEFVKNYSPRYPFLEIACYNSPNSIVVAGKESILLELSKEFKNSGIFCAMLGSLSSFHTSSQLEVKDHIYSLKFESKEPVIPTFSTVTTHLFNSNKLYDNDYIFQNIMKPVLFNETISNLYKHVENNQLGSEMIFIELAPHQTLSFYLKQLIPKDSNYFSNSNSITILSPLHKKKNDYLEIQQTISTCYCKGYDVNFKSQILIESKTNISNKSLPLYQWDDKEFWKDLEKQKRILQGPPMDTLGFSNEKSPILKSFETKIDIKKKPFQYLKGHIVKGKIYFPGVGYIENLLKMYPSQDIDIDSMEFEAPLILIEGIVTCLQSNVYKIGKNEFKVQFHFQDQKTKQWIQSSFANYHLSHRDDFDPTTNKLNIQNLISNNCNLTKLSKNQFYNFIKAKAGLSYNGEFQGVEKCYLGDNCSLVEIPFDTSNQDVETNINMIPILDSCLHGVHILYVEQCQMVLEKIEGLKYYSSTLILSKQKEQQKLYVFTRIENKDLINNSISASIIVMISDGTVFFEIESVSLKSLIPLKDPISIENPTDELFSSYLQSIDSLISEPSSYKSIYKRNEFISSGMSDLSRSDYQQFISTLLYTNLIKRNQSIESDLRNQIEFEEIKAKYCKNSKFERLFTFVIETIKQYDGINGNLNSWNEGNIDIYKILIKSTRIISKLLFPLQGEDTTIDTPQSLFENNLLDDFYNINGNTVIQNQLVGEIITQSIKPLINEKMVFRILEFGGGVGSLSIVTLNKINQLLEQHPNFQIDIEYTWTDISPSFIPDAKKLLSNIKGVTIIYRSLDLEESLIEKQLLKPSYYDFVIMSNVLHVIKEIKFGIDEIYKVLSPNGQLLFIETPYRMLICDSIFGVFDQWWGFTDTGIRVDRCCMKQKTWFKLLSESNYQDIIMSDDIKDCCFVIQAKKPSISSLEYKLKIDSQENDKIIVFGENDTFMKYLENKSTKQIIKIKTCQQFSDLITSNSKEINNQSIIYFIKTLNQLLIENFKEITLEYIQINQLLLSSGLSCKHILLLNQSTSENYLGSSISGAARYFDEFPPLKLYSFDFDKYSLNNESINIIDDIIEPIIKSMNNSNIRKELLVRNNKIFFERYKQEKRIKENYKSTSFENDKSLFVHLNANLEYELKSKQVKLKQNEIEVNVKATGINYKDYLVYTAMTPSELINHKGESNPEFGHDFSGIITRIGDDDGDNDNEFKVGDQVYGIWFNTTASHIIVDKEFLCHKPSKLSHTIASSIPVVYITSLYSLYNIGNIQNDESILIHSASGGIGLSALNILKWKNHKSHIFVTVGSKEKEKYIHDTYGDFITGIYSSRNKDYLKLIKRKLTELGSNKKGVDIILNTLSSSEHMVSNFKCLNHRGRIIDLSITHLNHNEYTCNNNFKYNYGYHNVEVLFVKGDIISKLLKNITSAIENGSLSTGIPIIEFNDSDCFNAIEFINKRQHIGKIVVNHNKENLIQELIKKTNLPIIKSNYQINSDHLGKNILVTGQSGIILEILKWIVKYSTNVENIIILSRSSLKWELELLVNKNKNKLNFIYKSVDVGNSLEIEKVIDEILMENPQINNVDSIFHYAFTQISCKEHEIDQVHLNVSHQAKTMGAINLHNQSIKRNWKLINFIMASSAAGLIGSTDQCSYVCSSNVLDTFSKYRKHVLGLPSICINYGLIESTGFVSRNQSVAVMLDGQGIRPMQTNQILGSLDLFIQNPSKSTNIILTSFNFNEFATGNLQQSNVHKFDFQFNCCLSQKSKLMANNQASENPVKDLLINNICELLSIDESKLNIDIRLIDYGSDSLTIVQIKNLIDKNLLIPNLISIQMLQNNSISDNIKILTDSYNKKKQNEQNELKNIKVGSFTKK", "length": 2531 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K45-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKILYLIIYLTLTIVKGAPLYNCKKLNCSSMNTNCKVFGCSPMFGCFETSKCPQSNVDICHTNHCDENTGSCYQIADTCNDGNNNTIDSCGPYGCVNTPVNPPEPTQSCEQKCNDNNPCTVDFCDFRGDCYHYETRCSDYDACTLDTCGEKGCEYRPMNCDDNNPCTADFCSMLYGCYHEPIECSVKVPCRTDSQCNRNNFCETYSCDLSSNICDYYTRDCGGNPCINNECRTGTITN", "length": 239 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K50-1", "protein_name": "Phospholipase D Y", "gene_name": "pldY", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIINRLFIIIVLFFVNVNSKIISESTLNSCQGGTIQIAESIPLGLDISTNLSTHDAWMDLITNAQESIDLGFFYFTLLGGSDLDPVYGGQLGIDIFNAIVEAHSRGINVRIVQNEPSESFPDTETQTLAKLGIQVRSIDWVSLVGSGVLHTKLIIIDESSAYVGSANADWSSLAQVKELGIVLKNCPTMVADTEIAFQQYWNAADFTSLPINDWGSNYQALFNNTNMASLSLNNNNNNNNKNKNNDNDGSGTNQMYEMFLAVSPPQFQSTYRTGDIDALMDAINNADQSICITVMDYTPTTLYNDPNTYWPLIDNALRAAAFNRNVQVRMLISHWNYTSPIIPQWLHSLNQVDNIQVRWFVVPDFSTNPQIPYTRVNHAKFMVTEKQSYVGTSNWSQDYFTVTGGLSYNVFNNDFTNQLQSIFNRDWNSPYTQPIQNF", "length": 438 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54K65-1", "protein_name": "Band 7 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNSIKKLSTTAIKFTKQTQRFNKRGFFKILNQYERGVVFNFGKFHTVKEAGFHIVIPFIQKCDIVDIRTFTYTLDKQKIISKDNINLTVDALVVFRIHDPKLAVTKANDCILLVNEMAQIKVCEILSHNTLDQVLHNRDKISNQIHDELKEALNKYGVTIEYLKLKDIHFDETIAKAIAKKVEAANLRDIKN", "length": 192 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KF5-1", "protein_name": "Protein LEG1 homolog", "gene_name": "leg1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSNKTIFLILLFLINFNSIYSFNFKKEIKISNDKINLPTYNPWIFQDRFNLYSILINSTNIPVFGEDNSNNCLHGLQLQFEWQNRSGRLEINQGHVNTKSWWGDMNYYLSIIPYLSAMKMGLVPVVEIVSINDQRFCSTYEDCDQEVLNNWDNFFQQIINIRNNGSEGDDQQLLKFMWTAHIGSIDKATKLFTDSLLLLPKNELRFGNGWAHFVDVIATVNFNTNYSTVYHLGQQLPPIMLNSNDTHPSSIESFTKEQRNVVLTMYEINDLSSNNLVWNSFMYLLKKMTKNEICRNLINNEINIFLNSPVPTIIEILFDILTNNC", "length": 326 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KK9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTEVPNQKHNDGGVGVTVGNFVKDNETNVNNNNNINGKGENDNNNNNNNNTIIDEPKLLNNNNNNILVIPLTTNIIDNELNQQKQHTLPLPLPPPPLPTQPQQITPPLPTQTQLPNNMLPSPRPIQQPKIRQQTQQQQAQMQQLQLQIQQEIQLQLQQQQQQQLQLQQKQNESEINGLFSPNFSSSSSSSLSTTPNMHSPLFNNNNNNNTTTTTTTTTTTTNSSTNNTNSSTQTKNASTNKISQDVIGVFDDTDTESEGEEYHSGRSIDFWNKDYKDIAWRCNWIDLQIRDLQYQSMVCDQLYHKVRRSKQKIIPDNKSLSSSIDNNNNNNLKSIPIETIDHSNNAITSSNIPYSNNEEEQQEQQQHPSQSIRTTSVVKLRKPRKLIRRPTVKLSAKQMTTDLEAHPLFTFHKGYFKFENAIKTNIINEMEIKYQEKEKPPKLLTLSEERLKQYINSNEDVDVVNLFATNESKRLSEKRRGRIPSDKKEKVSSHRLKSGDEIDGTSSSTATATTATTTTTTTTTTTTTNKKSRRSRREKKKEKEREKQEKEKHIKTKDEQKDREKKEKAREKELEKERKREKERIKEKERQEKERLKKEKELEKNKKKEKKLLKEKEKEIKEKKVKLKNQENIIEKDLTINNTTTKTTKSKKSSSKVKKSEQEGVKLENVEIEDEEVEEEEEEEEEVEDEEEEEEEEEEEEEEEEEEIEEVEDNEEEKRKEERRRRRRKRRILRRRKKLRRKQRKRQLFLQKQQQQQLLQQQQQQQQQKLLQQLKKRDESNGLSYKEIITPEWRDISSFANNDPSLPSPLLLSNPLLAQDIKNITTTTTTITTSEPISKFSTITEEELLIRQTTNGIDGTPMNGIGEDSESSGSEIELDEDAMKIIHARNEIEEKRRFFNTIKQIQMENPVPSYKRKKESLPVEFVAPTVEELLPSYHFNKKSIKLLGKSWNGDFEYYSSSDEDDYDDSDDYDSDDDNDDEDDDDSDSDDEDESDSDDYDSEYDSDLSDSDDSESESSDNELDGLYSSESEINHNSSGDEDEMDVELNNHHIPSKNSKNSKKQPVNNNVNNSNNLNGSSGGGKINSKPSKQQPRNSKANPPSKQQPTPLKQQPTPLKQQPTPLKQTTTPSKATPSPKQQSQQQQQQQQQQQQQPQQPQQPQQQQQQSPKPTPPLVSTTPPLSSVPLSPPTKTIRSTRGVSSLSNSTSSLPKQTNTPPISILSRKRNQSQSSVTDAPLSPTTTATTTTSPKPTTRRKGKLQETIPVEETKIIEETKPFEETVPIKENSTTTPLKRTRRQTKQQLVNGETTTPLTNGDNHVEKTDSNSTDVKVDPTSWWGDKQYKIQPVMEATVIRFKRVKNDDGDDDDQIQNNQKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNINNINNTEDLESKIKETKSINIPMEISTNGNDFQMKEKEGE", "length": 1472 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU3-1", "protein_name": "Probable polyketide synthase 25", "gene_name": "pks25", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDNSYLNNPQFDINNGNKEVTDDDNNKNNQDNLVAIVGVGFRLPSGENERNNTPQALWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGITPNEAQTIDPHQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGSSTNDYLTLNRNEVKSNVFGSMAHSIANRVSYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDPYPYKAFSILNMLSKSNGRCKSFDASADGFVRGECIGVVILKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPNGDPVETEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNENKNTSMIINNFGVTGSNCCLVLSQFNNTNKQKQQMKTKINNYLIPFSANSVESLKKYQSLIINSKENELKYSFEEFVKNQVFIKPTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKRSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGLGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGAGYIDNLLKLYPNQDLTINSIEFKTPLILSDDNGQFLQTNVYQTGKSDYRAQFHFKDNRTNVWVQTCTANFQLYNNGKVDKLNLEEIKSTKCNLSSIPWDKFYPHIKNRTGLNYKDKFQNTIECYLGDNCSLTEISLELPENFHDQESFFNTPILDICFHGSIVLIKDNCKLVLDKIDGFKLYTSNIPKNRFDHLSIFVYTTMKSTKSNSYNSTYTVMLEDGTVILEVENLICTSLTPVKDPLLIEIPTDMYYTPYLQSKDSQIQSPLEFKSIYQNNQDNDSLLIPNVVLETIKPLINEQMEFRILEFGGNNLSNSTLLLNSINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIKYSLNQIYQILTPNGNLIINEQQPNNENNENNEDSLKNLLVNCNFNSDIMMKSSSVSDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCNQDEQFQQQQQLINKFESHYNNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSITFEYVQINQKLYEFKSKCTHVLITYDSQSSNYLSSSILGAARYFDEIPTLQLFTFDFDKDSLINLDISVIDHLIDPKQNTLIEFFIKKNGKVYFERFKKGLKKNSFKSESYHQITNEQEILISKLDENLDYQLKSKDSILKPYDIEVEIKATGLNYKDYLVYSGLIKLKGDSVDFGLDFSGRVSRVGIKSSKEFKVGDEVYGIGQSTSSSHIIIDSMHACHKPSKITHVQAASIPAVYATSIHSLYNIGNLREGESILIHSGSGGVGLSALEILKSNNHSSPIFVTVGSEEKKQYLINTYGNLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDSNFKCLNPEGRIVDLTITHLNPNEFIDNNKFKYNFGYHNIELYYCEKPTIKKLLQSISKSIENNTLNYLIPITEFSNSNIKKAIEYINERKHVGKIVISHDTDITNKLIENQPKIDYSLLKSNYKIKNLGKNVLVTGQTGLILDIINWIMKYNSTVENIIILSKSSMKWEMEFLINNNKTKIKFYYKRCDIGGDSDSINKTFDKLFTENPTITNIDSIFHFAVVQITRKVKDIDMKSLNISHDAKTIGAINLHNQSIKRDWKLSNFILASSILSKVGSLDQCGYVSACCVLDSFSKYRLSIGLPALSINIGAMGGSGMVARSELVETVLNGQGYNLTSTNQLLGTIDLLIQNPGQESNNLMVGNFNFPVFNNFKQKIHQKFDFIFNALDSNSENGDGSNIKNSTNIKDKFLNKVSEFLSIDSSKINNDIKLMNYGADSLITVQLKNWVDKEWSPNLITIHQIQSNSIGMVCQIINDNFEKKK", "length": 2380 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54KU5-1", "protein_name": "Probable polyketide synthase 24", "gene_name": "pks24", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQNKINKAEILQVDDKHVEENLVAIVGVGFRLPSGSIENERNNTPQTLWNNLINGFDGVVKTSERFNDNFFKNHEIANNYSGLLPLDEVKSFDPLFFGINPNEAPTIDPIQRLLLKCTWEALEDSLIDPISIKGTDTSVFIGCTESDYHNINKNEVKSNVFSSLNHAISNRISYCYDLHGNSITLDTACSSSLNAIALGYDSIKNKKSKMSIVGGVNILLDSYFFKAYSSLNILSKSNGRCKSFDASADGYVRSECIGVVVLKNLKDAIKDGNRIYCTINGASANVDGIGYSDKSNFYSPSSISQSENLKNAIQSTNGTVKPSDIDYVEAHGTGTPTGDPIEVEGISKVFKDTRSTDTPLLIGSFKSNIGHCEAASGIASLIKCCLMYKNKCFAPNIHFKTPNPAIKFKEWNLKVVTEPIPFNKFKNTSMVVNNFGATGSNCCLVLSQFNYNTINNNINNHNNNHNHNHNHNNIKINNYLIPFSANSVESLKKYQSLIIENKEYESQYSFEEFVKNQIYNKSTSLYQRSVIVAKDWNDFNNVENQVKYQTSSSTSSNITITNKNNNPITVFVFCGQGSQYNTMALELYKNEKVFRNSMDMLDNKMKNYFGYSILEKLRAIQDSDKCSVHEQTMAQPSTVIIQVSLYELYKHWGIKASFMLGHSLGEVTTAYCSGMIDIDQLCYLIYHRSTLQIRTNGSGKMLSINISSDEYKTNYMSRYPTIEIACYNSPSSIVIAGNEQILNEISKELKEKEIFSAMLGSLSSFHTSSQNIIKDDILNLNIQSSQPVIPTFSTVTSNLFNESTIFDSEYFFDNISKPVSFTQTISNLYKHIEDNQIGSNIVFIEIAPHPTLSFYLKQMIPKQSQYFRNGESISVYSTLHKKKNDVEEFQKSISQLFCDDAYDINFKCQFNNINSNIEAISNFNLPLYQWDDQHYWLNKSIEHKNNLIGPPISILGNSMQDSNPFIKSYQTIIDTGKDAFKYLKGHNVSDKCYFPGTGYIDNIFKLYPNQDLTINSIEFKVPFVLTDGIGQCLQTNVYQTGKSEYRAQFHLKDEMNNQWINTSNSNFHLNSNDNYHEEKQKLDIQDIKQTKCNLSSIPWDEFYSLMKTQLGANFYGIFSKVVECYIGDNCSLTEISLELPENFHDEQSFFNCPLIDACFHGTVILYIQKNCKIVTDKVEGLRYYASNIPKNRDEHSSIFIYSTLKSSPSDDLLSSSIVVMLEDGTVIIEVDNLVVKSLTPVKDPLLIETPSDFIYTPYLQSKDSQIQSPLEFKSIYQNNQVDDGLLIPNVVIETIKPLINRKMEFRILEFGGNNLSKSTLLLNEINSLLEENPHYEIDIEYTWSDNNSSILKDAKLELSKVDKGYLSILYRSLGLDVDNSLLEKQKLNPSYYDLIIVSNISNLTKDIEYSLNQIYQILTPNGYLIINEQQQQQQQQQQQQQQQQQQQQQLLNNENNKESLKNLLVNCNFNSDIMIKSSSISDSDIKSIIIQAQKPSLKLQPKTINTFDQVILYCYQDEQLQQQQLINKFENHYNNCKIIKVSTIEEFYKLSTTITNNSIIYFIKSIEQLTLENFKSVTFEYVQINQKLYELKSKCTHVLITCDSQSSNYLSSSVLGAARYFDEIPTLQLFTLDFDKDSLTNDLDLFKTIDYLINPKNNIQREFYIKNSGTVYFEMYKKELKNLKNSYKSESYHDLSKQQDQLVSKLDEHFEYQLNSKQIDLEPYEIEVKVKATGINYKDYLKYNEMIKVNEAGIGFDFSGVVSRVGIKSSKEFKVGDQVYGIAYETSSSHIIIDSLLACHKPSKITHVQAASIPAVYSTSLYCLYDVGNLRDEESVLIHSGSGGVGLSGLEILKSNNHSSPIFVTVGSEEKKQYLINTYGDLITGIYSTRDTNYQKQIKNKLIELGYETHGVDLIINTLSSEFMDTNFKCLNPKGRIVDLTTTHLNPNEFIDNSRYRYNIGYNSIEILKVGKSTIKKLLQSISKSIENETLNALIPITEFSNSNIKKSIESIKERKHVGKIVISHDTDIIDKLIEKESMIDYSILKSDYKIKNLGKNVLVTGQTGLILEVLKWITKYNSTVENIIILSKSSLKWELEFLMNYNNNNNNNNNNNKIKYHFKKCDISNWNLINKTIDQVLKDNPTITNIDSIFHFAALQINKKLKDIDMNSLNVSHSAKTFGAVNLHNLSIKRDWKIINFILASSVVSVLGSFDQCSYVSACCVVDSLSQYRKSIGLPSFTINIGGVSDRGYLSRHKLVEAVLGGQGVELISPNQLLGTLDLQIQNPNMPTNAFVNNFNWPLFKSFKQKLHQKFDFILNPINVDNSISMENDTNQSSSSTNVKNKFLNKVSELLSIDPSKINTNIKMINYGADSLITVQLKNWVDKEWSPHLITIQQIQSNSIGMVYQIINDSLDKKKKEMDEKLLPITAKTTTTTKNDPNDKTEYKYIAGGDCCREFSIKFHYSSVVNFII", "length": 2471 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LI2-1", "protein_name": "DNA replication licensing factor MCM2", "gene_name": "mcm2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSQNNNNNNNNNNNNNNNNNNKRKTKTPSSVNHNNTKINEDKDLYNFIDKIRDKTDKSHLEDEYDEDDNTKDGKFNKVEDEIKNDIDSEEDDDDIIEDNEHLYDGDEDSENLSSEGEGDDLLDEDLQDQDEEEVLGDEDNHYEMEGLDNETYEDIDKDKKTEVDSILTKRDREEQKTRQATNRHQYRISSFLLDENDENMVDEDTENNKLLEKRKANLIKKRRETIRQQNDNIKKDYDGSVPSFKDGFVNSERYFEDGDGDDDDDDDDFDIGDNGQVVNLEEPDKDKCLREYVCMSGPRNEISKQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCASTVFGVWVAEIPTEMIEIFDEVALKVVLRIYPNYRNIVKSIHVRITHLPICESLRDIRQSNLNKLTKVGGVITRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTVYRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITGIYKHNFDLKLNYSQGFPVFSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTGLALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAVGLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRELARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNKISQLYTDLRRESRAGGFAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLDSFINAQKNSMYKNLRTKFAPYVIFQKDINQLLTQLLQTLARDFSNYHFARSGDIPDQINIPYDDFDTKARELGISDITSFFRSNEFTSNNQFTLKKDKSTIIYYRNK", "length": 1008 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54LX5-1", "protein_name": "U1-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKITESNNNNNNNKKDNNKHWCKYCKIFIQDNISVKNHEEGWRHKNNVTRFVSTQNRDKKYQERDQKEAEREINRIKNTGARSFREKDLSRVLDEKKHQQQPQQQPQQPQQQQRIFNNNSNNNNNNNNNNNNNNNNNNNNNNNSNNNNNYHQPQYPTTTTTTTTTNTTASNKNCDNADSKFKEIQEQQRQLLSNNDYYNYYQDRQQLIYDYYQNEGNQPIPEPPLNTSLYGYTESPLLKSRLDSSTDTLSSSSSSTIISPSHQKKRKQDDTNSPIPAKISKDECVNNENKDKSNEKENELNNNNNNNKSGEGEEGEESDDNDDDEEESGSGSESESESSEVDQSESIIGQWQTVDPIESAFGSTRKDSDDEKDKKDKKNKKDNDENKRDEKDYSDVSDADSEEESVNITKRAMANHKKPITLTNVISPTIPSTSKNFESVLSFNKSGVFSLNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNEPPQPTPQITLKFNKPLKQRNTRKTNIEDKQS", "length": 514 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54M95-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLISILFFLFGILFFLKNVESASDVVCSFGYQACGNNCYSPSSGQKCYPGGVVCSFGYEACGNNCYSPSSGQKCNPGGVICSFGYQACGNSCYSPSSGQKCYPGGIICSFGYEACGRSCYSPSSGQKCYPGGVICSFGYQACGNTCYNPSAGQRCFN", "length": 158 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54N59-1", "protein_name": "G domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDLDYAIIVLRHHLESNGRFFEISKDDVKNRVTIKNKLTQEERYIDFGEIQNFIQYDEFEYNLLANGFQENLSILKNSILPLTKAPDSCSSNRGKTIGNSSLLINKVNGLIDDDKDTIYLLLIGITGVGKSTFVNMVVNYIEYSNLKDALENATLEQIYTIASKIEIQDENKTHKFSLGDVEDYKIGSSVTQYSRQYRIKLPDGKTLCLIDAPGVGDPQGTLQDNKHFENILHEISSLKKLNAICILMRPDETRATVLFKYCLNQLLLHLHSSAKDNIFFCFTHTRGTMYKPGPTRAILEDHLKKMKDQSDIEINANEKTFCFDNESFNYLAVKKYNATAGIETNFSEDDEFDFGRSWDRSSKEFKRLLEEISKVQPHDVANTICINNARTMISNLAQPMSTCISNINTNIKLMEQQSEKLRNNSIGDESLLYIPVSVVIAEKLENSLLVCTKNGCSSNTDNPCNIDVVSPKWYSSLYWCDNINKMGTCKKCSNTGVLPCLWFDHQVVTIKETPQLNQLPGTDKKTIGQRTKSEIFNERELLVTKMGERKIQFQEEYDTIKTAIVDFSVFLWHHSLIKFNRYYEDYINMQIKQLENSENSQELIQKLNEHLSEYKASVEEIKHNVQNNKASVKTQKEIFATFDKLLTLPNVGYIIQNQIKLKQSSHYKSEAVEIDLFSKMKNKTKQIIK", "length": 689 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ND5-1", "protein_name": "Multiple inositol polyphosphate phosphatase 1", "gene_name": "mipp1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMVKIKNIIILFCIFGLLSNVSSLSSSSSSSQSSDNNGNLSPIQDYDLEFLSKHLTTKTPYWILTKNGDSNSQGDGSSGNSNSNSNSNSNSNSNSDSSNEPPEQCKLISIDFIARHGSRMPVLNSIEKLKEMTTSILEYKEQVNQGFNWIFNYSVPYPSDIAGNLILQGQYEHYNISKRLLKKYPLFFEPMKYKPQSYSITSTAISRTGISASAFSYGLLQGTGSLGVDGFQPVFIETASLDQDILLRFFATCNQYVDQLKNGTLINKDEQTKWNQMVFPNISNEISERLGLSDIWLPTSNVISDIFEACAYEISINNISDHWCSLLSKQNILDWEYSQDLSNYWLKSYGHEINYQIATPLLNDILSGFDIYINNNNNGSSSSSSSSSSNNGDNSGSNGSSGSGSSTSTSSNDNGSTNNNDNKVEPTSILRFGHAETIIPFISLLGLYKDEQKLFANSSTEQIENRKFRTSVVSPYASNIAMFLFDCGSAADGFKILVQHNELPVLVPGCDEIYCDYQQFKSIFKQGIDNFKWNSYCNINDDDSGSSGGDSGNGNGNDSHSKKSSYFLAIFIPITFLVGGTIGGIFTYFSYEKIMQVKNRKKLTQYGNDEFISSPKSKSFSFKPTKFDSRSPLIQ", "length": 635 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54NT2-1", "protein_name": "SH3 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKITTQFARTRQMLFTKTGHSEETIDVQYHYEKERTFSTEERLVKIQKNSKKLIELYKDLNKITTDIAQDACDLYDTQDPMWTPGSKLRDVATNNDKHLLDYTEQMAEPYTKPLSDYISQYKEARKRTEELTTRKVDMDRYKNEVGKLREKGAGSSSKAKLAPTEEKLRICKEGYDSLHEELLNDLPRLNEDKLIFIDYLVASLIKYQSEFHKKVSYEWSPLPSLTKHVDEYSGRDHQPVITSVERSAASINLRSDPVFKSNASIKMKPGAQDQQQYSTVDKDIHQSPNPSNLNLQKSTPNPYGGASAPPPLYGGGGSSTATALYDFTGVDSSELSFRAGDIITIHKSEGEWWEGELNGIYGFAPGSYLRMN", "length": 374 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54PW0-1", "protein_name": "Annexin I", "gene_name": "nxnB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEYKEKEINTSSPSSPSKTQISNIENDSISEKAQEPISEKVQDPISEKAQESISEKEHIESNNVSEIIDLIKSGDQHLNNNNNNNNNNNNNNNNNNNEEENQEINYNDNQLSNEEIVEDVKNSNINNNNTIEKGNSSQNNNKNNNNNYHTEKCDYCLICKCYDYGEITHNIVEDSEILKQSIRYSYVDDTSINSILAHRNYAEKEAIMKKFNDKYNKSLETELASHTHQKYRRTLISILTEPSIYDTLNIENSIKTKNSNTLLEILLTRTNEQKELIKRIYLVKYGKNIEHDIIAKFSNGANVNGNMMKQLLISMLNNDRDSNSNQSLDMNLINTDSNRLYQAGEHKKGTDHEVFIEILSKRSFSHLSELDRVYENSNPKGHSLRKAIELEFGVSKSIKQVKISLLDILLFSKEPSKYWAEQFNRALTSGSWGINEIDLTRLTITQQHQASKIKQAYISHYDNSLINEVSSKTSFRYKKIILSMLTV", "length": 487 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QB4-1", "protein_name": "Kinetochore protein Ndc80", "gene_name": "ndc80", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MHNNNLTYQQYQQQQLLIQQQQQQLLYQQQLLQQQQQQQQQQQQQKQYSHGRPSTLGLPSRKPPPMQPQPQPQIQAPIQLTFQQQQQLLQQQQYQFNNNLNTINNNNNNNITNRHSMVTPSTNLGGRSSLGPPSAMLTNNNNNNSNIRNTTFISNSGGNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNNNNNIHTQVQPKKSIAPSKSNTISSNTTTTTTAASSSSSSNPSITLRQETRPVNDSKFQSQCLLRLQQFLSQSEKGYPRAITKDNLMSEINGLMKFLCLHIDPHFKLPTEKPEEEIISFFKMMGYRSAGFTKRVFSQVGNAHTRGHLLGAIIWMVELIEYDQIIRQMDSHIEREILNGNTIDENGNLTTTTSATNTNEDGNFNLTTQIFSKHVFKSYEAFLKGDDGNHVDQFLEEKFNEVNELIVKECEESMERQKKIKQEIVNLTQYITNDDIDQLNFKLEQTNQEIIATHDLINDNELEDQKLDQEIDQNQTHFQELEIQQKEHQKKKQEFESRIQIQQSNSVDAKRINQETFELKEELDKVQREQSRHDQLKQEKSKEIKQSINEIEKLIQSYKEICCKASLVTNDNLIIEKYRIIFTHTLNNNNNNNNTNNSSILNISNNIINNNNNNNNNNNNNYEEGIISISDLKLVIKNLQELNLEISQNISKIKQDLLKTSNLNDIQKESISDKELELARIKQKHDKQKNILKQEKQDQTFDITQREENIEQLKSSNKKLIDDGVRELEKTIQLLESQREEHSRLKIDLKQSSEQMKLQYLKRIERFISHRQLIGSQIFDTLRQMEELSLTQKILFPPPPPPPQLSQQHQQLMQQQHQNNTIDIDE", "length": 855 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54QD2-1", "protein_name": "Probable cytochrome P450 517A1", "gene_name": "cyp517A1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIINVFLFLIILFLVKDFVKKNKKIHTKSPSGPIAFPILGNVVQIRFWELFKIQEHELFGGYSKKYNGVVRAWFGERLFFFVSNYDVVKYFQKDENFHNRPSVLVPGWRYASSNGLGVMSSSDDKWKRAKSSVSQSLRVRTTKKLMEEKAIEFIDSLEKISNNNEIFYPKGHIQGYACSMLFKYMFNQDLSVESGMSRTIGNAVEHVFGNLSKLTAFDCFEIFSPLYDWFFTRRLKGCDIVRQIISSQNENHLKSIDPSKPRDLMDDLLIEYGLNEITKEDTMQINQICFDIFGPAVGTVTITMNWVILQLCNRPELQEIAYQEIKKAVKDDEYVNLNHKQNAPYIVAFIKETMRLCSNGFGLPRTAKNDQICGDFFIPKDAIIFINYLEISQNEEIFKNAKEFNPTRYLDESLPVPNIHFGVGQRACPGRFVAIDKMFLGISNLLLKYKLKTQNGEKIDDSIQFSVSLKAKDYGIKLEKRI", "length": 483 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RM4-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKVILIYFIVIYLINISFSLKPYQQQQQLHNFNIIENNNNNNRNEKVIIAHPKIPPYWLIENEISNPNDLISFKILLKQNNLNKLNYLFEEISDPKSKIYGEFLSINEINELVKSSESDFNVVLEYLKSFNIGNIENGSEIKVFSDYILVETTIEKVSSMFNSKFSNYKNKNNGNTRNRLNGPAYLPKQLLNSIDFVTGLSEFFENNFKIENYLNNNNKNNGDSDSDSGSGSGSGSSNSYNGGLDDILITPKVLKSYYNVPNELIGKFENNSIGVIAFNDYFSMGALELFDEKFNITTTKDNLKIIGNDCLGKGCDQYESDLDIQYIRSMGENISTDFISFNDAQWILDYLHSVLLMEKPPLVQSISYGWAELLQCDVSNGCSTFGYDSKQYVDRTNSEFQKLALLGISVLVSSGDDGAPSMGGSSGNCPIDGTVYCPTGGCNHTKTMCPEFTIYNLNGGSDSGGSSDSYCFFPMGIASSGCTNILGDPSVLDSGMKIFSEKNKQCNLAIEYDRTNLPHVYSECECKDLVNVTFRNYHFTQYQFNENNGALFVAEYPSSSPFVTSVGATQFLSRDEKITTEVGCTILQGAKITTGGGFSSFQSQPKYQQYAISQFFNTSFNSLPPSFSYCPTNRGVPDISMVGHNYKIYSSDGNNKDFNQCPCKSLPVDGTSCSSPTLAGLIGLINDQLLLNGKTQLGFLNPLLYQMAIDEPRIFNDITGDSSNRCSRSYCCLYGWSTSSNTWDPVTGLGSIDFNLFLSYVLKLKGI", "length": 767 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54RX1-1", "protein_name": "Translationally-controlled tumor protein homolog 2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLYKDLIGNSHDDLLTDRYEIKVGDVTFEVKTKMITKDLNVVVNNNSLGGSISTTVDNNNSITLSTNLEDEFENVEAAGTFQINNLVEQLRLVETSFDKKSYLAYMKLYIKDLINHIKQQPSNSDNEKIEHIQKGIQSFVKTMMDGENFKKYSFFTGSSMDANGLVALMYYKDDDPTTPTFVFIKYGLLQVDV", "length": 194 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S19-1", "protein_name": "PHD zinc finger-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKNCIVCSKVGQYPLNLVKCYECKSYYHKFCLQSTKIPRGEWYCSSCEIERKNKKNKKRKLDGAGKKNKKNNKDDDDDNDDDDDEGENDEDDEDHQDEDSGEEEDEEEDEEEEDDDDEEEEEGNEKNKIKKRKRIPINQSPSIKKRTKDIDSEEEEEEEEEEEENDSEEERRIQKRKNKIKQQQQLKMKEKKQREKLRKRRRRTRSSRKDDNDQDDDDDDDDNNSNNSDDNDQDENKNKQKRKRRKDKKKDDDDDDDQEEEEEEEEEIVTGKRKRRSLNKVQPNQHLNNENEEDNEEEEEEEEEEEEEEETDSSEEFLENLVCSSCNTGKDEDKILLCDTDNCSRGYHMYCLRYPITSVPKGDWICDFCRFGDISADLHSADDDEDGAINSQKEIEKQKQKQKEKEKEREREREREKEKEKERERERERREKEKKDALRSSFSNIPIPKINNINGSNGSNSNNNNNSNNNGSGVNRQSPPKVISKKSPQQSPKPLKSPTSSSSSTTSSPPPLHQQSKVTSKISPNSQQSIPTINSNINKSPPSQSKNSPPLKPLTPDLKKQIPITNITTSSTTTTATTTTTTTTTANTSNVATTTTLLKPSSQKKPTILSDKKQLNTSGTNLPMNGKKKEDLESSASHSILDMIPPNNKLFNNSIQSAPISWDLSGSQHKLSTSSSSLPNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIKLQQQLQQQQQQLHQQLQQQQLQQQQQQLHQQLQQQKLKQKQIEEEQEKEREQKRLENEQKLLLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQEFIDQKELEDKLLSQFDNQNLKSPLSLTSTTSSTLSHLPQSTFESSTILSNKTIKQKWKSRILFETDQICQCEIIQIYGMDFKVNPFQNNITSKTLELSFNQVSFDNLPKPIRDEFITKSSTPSTCLDIGAIDLPNSALLIFLPEIPNQSSLYHLIIHFIENRVAGFIDLSNDLSLYIYPYQTSIISLDLIGILIDKKSLSPPSLILNQQQKQQKQQQQEQEQQNQSFDIKNICYIGINHISMNKILTSQGKNYFSFSNFNELTLSSDIKNFDLVVVDNKMVNNQTINKEINNLMQLQPTTNNNNNNNDINNNHDTLLLVIKDVEFSKWLVSQKKFPNSLEIQKIFQQQILFKQSRCIFLLDNSIIIENESSYFVEFISSFGKFKNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNDWTIKISSTIFDELLPFGHQSNVKKKIDEIKRGINQQLIVSYDFSPMVPKQSSDFLLLALRIAHSKKYKQVFLITSNKIIQNQSKRYSNLNLNCLSLEGGIDYIKNINNKFSLKI", "length": 1361 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54S56-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDLFSHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVGECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54SW0-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "NQAKSSTIQQPTQTQQSNINNNTAKPRAAPPLKLVITNSNPSLKQKPQSQQTIPQQSVPQQSIPQQTIQQSVPQQQPNQSQQVNVNRTINPQQQQQQQQQQQQQQQQQNINRTAPLPQQSNYKPQPGVIYQQQQQTQYRVGTPLTINRSPMVGMVSKQPMSSSQQQSQSQQNIQRVPCQGKCCAGLAVKPLVPINSITAKPPPYSTMGPRGPISGGFVRTSPTGAIIGPSPQQQTMSRAMVNSMPIQPQIQIKPKPSPLNNGGIPITTTTTTTTNPLNKSSPSTLTQSSNTLASSNNNITTSNSLSSSTSSLPTTSTTPTTKPKSKPRSKSNSNSQTSSSTTSSSSTPSTPTTNSTKNKENTTPNKGDDSGTDNEKSSLSNSSKLLPTAYTMDQVLPFNPNQMFLGPEDKYIKSATRTYHKIPTNPSVMSNNRGAEIPSSLEYILDIPIIHDEPSSKNNPTWGRLILDALRRLVANKKTTRITERLKLDNMYKDMDSRSNQDKLDWKNGLVNEAQLNYLLSFLSNTIPFPDTPEKNKNKYLSSSDSQIINSNDQSNSLNSNNSSNNSTTNNNNSSTTTNSTNNIINNNNNNNTSSVPNSTNNSNNSSPEQQDVIDMELKLEPDNSMNFPIEINMDSLGSYIDDSFTFDNSSYDDTATISSDDKNLPITTVMPPTTSTTSTPQTITNTIPTTTPTIISPPTITTTTTTTKTTSPPTITTTTSPPTITTTTSPPTITTTTTTINSITPTTSTSSTINSNTTPMLDIVIDPVISLELLDENHQQQQNKEVKEENVHSKQQPPQQQQQQQQQQQQQQQQQQQQQQQQQQQQEDFMIQVQTSDLETQTQIQQDKEEIQVKPIVDSKKSGNSPTQIQQQQQHQQQQHHHQHNTLTQGFEFGMMMDIMNSPSSTSSMKRKRDDVDQPINQINNSSMVVQQNNDFFSDFNTIEAPFSSSHHSSQLSFQTPFSPDIVIDSDFQNKKRIVS", "length": 981 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54T36-1", "protein_name": "Probable polyketide synthase 19", "gene_name": "pks19", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFGNKEIAIVGIGFRIPQGKESINNGSVSHLWNNLKNGFSGIVETSERWSDNINLLGEVNNKFGGLLPLKEWSDFDPVHFAINPSEVPLMDPQTRLLLKCTWEALEDAFIDPIDIRGSNTSCFIGCSTLDYSTTNRDFNETSENYFASNVLHTISNRLSFSYDIRGPSMTIDTACSSSLNSITMGFQSIQNGTSNLSIVGGASLLLDPYVSKSFSFLNMLSKKGKCKPFDSEADGYIRAESCGIVILKPLSDAIRDGNNIYCVINSFSSNVDGGGLNDKSNFYSPSKQSQSDNIKLALKSANMKASDISFVECHGTGTPTGDPIEVEGVSMALNSSTTSTPSKPLLIGSLKSNIGHCEAASGVASLIKCCLMFKNKHYAPNVNFDQPNPKINFKDWNIKVVTEAIPFTNINEKPVSMVINNFGVTGSNCCLILSQFIEHSISLNGNNPSYPIESQQQIFLIPFSANSVKSLKNYEDLIINDNNLSTNSFKEFVKNQIYSKSKKLYQRSVLISSNWDQLKTKNKYFKTSNDKSSNITIKRNQPLIVIVFGGQGSQWNKMAQQLYECEPIFRSSMDKFNKELSKYYGYSVLDKLRSIKDDDIISIHQPIIAQPSILMLQISLFELYKHWGINVSFIVGHSLGEIATSYCSGMVDFQTVCKLIYHRSISQNNTNGCGKMLSVNISHSEFIELYSNKYPTIEVACYNSPTSIVIAGNENILKEISLDLKENNIFCAFLGSLSSFHTSSQNSTKNEILPLEIPSRQSTIPTFSTVTTNLFNHETTPFNSSYVYENIIQPVRFSQTISNLYQHIENNKLGNELIFIEVSPHPSLSFYLKQMIPKSSSYFNSVSVLTSTNKKNSNDLDEIHSTISQIYCLGYDINFKCQFNHNDDDVNSIRNNSTIILPNYQFDEQYYWKVDINFEQYRLNGPNVFNNLGKSMINYSSNNKSYESIIDINRNPFKYLKDHIVKGKYYFPGIGYADNIMKLYPNKDIVINNLEFLAPFVLKENVKHILQTNVYQLGNTDYRVTFNIKDNKANQWVQTCTGNFQLISLKDNNNNNNNNHSSKYNINQLLSECNFTTLSKQEVYKYSKLRSGITHLGTFQGIEEFHFGNDLTIARIQINYENFDINGKPVYQTFDKSFFNIALLDNCIQAITGFITNSSQFVFERLEGLKVYSENIPTDKLKYKNIYCQAKFISLEADSYKSSVLVLLEDGTKLLEIEHISFRSTLPLIDELLLNNPTNELFTNNLQCKDSLVNILSIDNNETSSSSGSSNTVTEIIKQTIKPIINEKIVFRILQSFSDSELSKQIIEALNQIFDNSLQEIDIEFTIIDNSNDKLPTLHDSSLIFKNDITQLKPSYYDIIINNNNDETIIKPIFNILSSNGLLLLIIEDDIGIRFNINNLIGVGFNENKIQKSNKVIQSQKSTILSNELTVVPNNKNDNIIIYCEKHSKYTNEFKKLISNNHTNRKQTTISNINEFNQLLPSITNDSIIYFIKSMEQLEMNNFKQITMEYIEINQQLLKHSLTCKHVLITIDSQIKNYLSSSIIGASRYFNEFPSLNLYSIDFDNQLSISSLLNKIINQLIENSNNHIQREYIIRNNSIYYEILKNEKNIKSNFNSNSFEDNDFMTLLDSTNLEYKLASKPKKLKKNEIEVKVLATGINYKDYLIYRGLVVIDENVSISKNPLGLEFSGIITRISDENKNCEFKVGDNVFGVSHDATASHVITDVLYVSHKPNNISHIEAASLPIIFSTCLHGMFNIGNFNIDDDEVILIHSATGGIGLATLEILKWKGHKSPIFVTVGSKDKEQYLIDNYGSFITGIYSSRNKNYVNEIKSKLNQLYGTTGKFNGVDLIINTLPNEFTHSNFLCLKERGKIIDLSITHLNNNEFLNFNNFKFNKSYHNIEFMHINKRVVSRLLKSISNALNENKVKLIPITTFQIENVKEAIEYINQRKHIGKIVLDHSCSNGSIGSDGLLNQLIESDNNEKNHTILKYDFKIDTKNIIGKNIIITGQSGIILEILKWLIKYSPPTESFENIIILSKSSLKWELELLINKTISRKDNNTKFHFKIVDVGDSIEMRKSINQILLENPNIDNIDSIFHYAFTQVTKEVEEIDIESLDISHNAKTMGAINLHEISIEKSWKLKQFVMASSIASLFGSFNQCTYVSANLVLDSLSRYRKSIGLPSTCTNWGTIKSSGFVSRNDSVSKMLDDQGFIPIPTNIILGSLDLQLQNSNKYSNLIVSKFNYDSIKKFASETSTFQRLDFILNSIKEKDNDNNGGENISISESIQMKFLNKISELLSIEQSKINTDIRLGEYGADSLTSVQLKNFIDKENKSNVITLQQLQNNTIGVNIQIILEQIKKLDSNETKGKSKKIIKKDSAPSLEYWRNEMKLDESIQAIKMNPIDFRNDSKVFLTGATGFLGVHLLSNLIKSPNCSVVYCLIRNKKSEPNPINAIINNLKHHKLYHFHNEFELSKVKVIVGNLASPLLGLSKLDFGFVSNQINLIINSGADINLASNYEESKVVNIGGLIELIKLSTTGDYQKPIVGFSSISVFFESPNCKEFDEETVIPTIENINNLPGGYMKSKVVVENLFREAAKRGIPSMLIRLPIIFSHEETGIGHDSDFFQLIIQSCYAVKKYPNIDKNILTSPIGWIGLNTIKMIGNEKCWNKSSSNQLNIYSLNSEVSSIKSSFSFLEKQYGCEMVEYEQWKNIINQSKILSCIKFKTFHSLDRLNGVYNLGHGFGVSKKTKELLQSMNSYEGGMVNEKIIQNHINYIFKN", "length": 2778 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TD0-1", "protein_name": "Peptidase S8 and S53 domain-containing protein", "gene_name": "V4-7", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISKTSLLLLLLSIVALASAISVQRVPIADVTSAPAHFVQNKLAKSYELVQFKILLKQRNLDILEEKFWDVSSPKSENYGKFLSKEEIDSIVAPSPKDVKVVVNWLIDNGLSKNEMIVHSDFIQVRTNVGKASTLFETSFAHYSSSRTALKRIRVVGQASMPMHVLAKVDLVLGLSDFIEDNKMSESMRATKKQVQGSTVSITPAVIKQYYGIPTGQIGVESENFQSIAAFSDFYSSGALQFFDQKFGIDSSTVRVKNVGQNCIAQNCDQMESDLDVQYMTAIGNNITTLFLSSGNGEWIIDWATAIQQYNPIPKIASISYGWAEVEQCEITNSCSTLGIDSVVYVARSNVELQKVGLRGVSVFVSSGDDGAPSFGAASGNCPIDGTKQYCPLGGCNHKSSQCPMITIMESNGTQCFFPMGSESNTCQSMLQNQNIVNGINEFVSSNSKCQVALEQDTQQNYHIYSSCTCDKLKPYSDSDAGFKIVGYSYDQDAGTLFQPDYPASSPFITSVGATQITDVTKPEIVCSVATGAIITGGGGVAITQAQPSYQADAVATYIKSGTLPPSYSYNATNRFYPDLTLVGHAYEIAVPNTLTSNTCPCALESVDGTSCSSPTLAGMISLINDKLIGAGKPTLGFLNPLLYQAAKEQPNVFNDITTGANNCNRAYCCQYGYTATTGYDAASGLGSINFKNFEQYVLSLN", "length": 702 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54TX3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLIYAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYFKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKAHTSTLNDMCRHWGVFRVKFYQNHPKINELPDCIRNDNDEPLKLKEIYELMIKDRHPTPRRTEWQKLWAVRYNTAIPKVFININSISHQKGRNTLFRFFSRSLPGINHERDTRCKICGHLFRDPYSHLFTLCQDILDIEKTIISTVNKLSFIKIHRWSMDTLDISKYNRTERIFPNLIGIIAHQLWKIICHKLFNTDESKPEPKFEQKVIETELLNLIETEKFITLKKIKHDEAILKNTNQDLHKYKFNKAWQTPAAPNPLPI", "length": 1097 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54U20-1", "protein_name": "Peptidase S54 rhomboid domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIYGDTREFRNIHFHLNNIRIVGAIFGQDGFIHKKIPLATKVISIICSILFALSLVAPSMFGSYKTCLSIESLTNSFLDNLYRIILSNFAHLSIYHIVYNMITFLDLAKLERLTFGTLKYFYLLFLFGIITNLICLFIYFIGRNNVCHLGFSGVLFALIYIESNSSGRDVFLFNAVKIPSKLYPWAMLILAHVFVPRSSFIGHFSGIVVGILFIKGYLDIFILSNQKLSEIESSQLMNIFTTKNSYFPIIKFGGSRRSYNTDRKSLDGLFFELKNLFNPQQQQQRQQQRQQQQPQSPQPQQPQQPQQQPQQQPQQQPQQHQRDNFRNDNNDNSNNYDEYDFSK", "length": 343 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VC1-1", "protein_name": "ABC transporter C family member 15", "gene_name": "abcC15", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKKIKNIINKIINFFSTIYILCKIYLYYNIKNRYEAYNILSVYGDDDFFNKPCPEDSSNWKDKLTFKWVERIIFVGFFRAPLNLNDISDLPSSLKVENTAPLLKDIIFNDSTIPLIKHIYSKFLPRNYIATGLFVFVSVFSFITPLILKNFLSYVEKIDEQKHIYIGIIQCFLLFLSSFINMASQQYSYWFGFKTSLEVKGALETIIFEKMTKLSNLSKKNYNIGSMLNLMSVDTDFFQYFFCHYYIEIFLFPIQILSLLGFLIYVIGIAGFVGFLVMLITIPLSSFLGTQISKNLSTSMGYADTRISLTGELINGIKFLKQYAWEKMFCERIEEQRKLQLKYLYIRIIYWVLVQIVTQASSGLVLVSTFTTYTLLGYEVSLEIAFTSITILQNLRRPIESLPDCLHKFISLIASAKRIETFLQSSELQNQPFIHNQSGLNDILIRNINFNWNEHNLKLKNNKNNQNNNQNKRSIILSSGEQFEITNDFTFDGIDIQDDNYDYEKEYKINYNNNEEEENFMTDCLLKIKPLIKDRRLQQQQADYQDLLSINLPPPPSENVDFKAPKGLLTIISGGVRSGKTSLASGLLGEICKAVDKSSPDSVNSILSTIQQPFLQSTSFRENILFGKPMNMERYIKVIEACCLAPDLLAMGEGKDLTEIGERGINLSNGLKHRIQLARALYADSDCYILDEILSSVDPEIANYIFQHCIKGMMKGKTVILVTHQIQFISSADHVVVVDNGVLIQGTYLELLRMGIDFEMILKEKENRIEKQIVQLQEDEDYYEEVEILDFTMNNNNNNNNNNNNNNSNFNGNNKLKRSSISLPKGISIESIISKDFDQTTIEKAKLFVQEDRNKGDPGWIIYKKYIRMGSSISFFIFTCIIYLTSQIILLLSDYWLQSWASHDRLNVSEPTDVHYLLIYLAYIGGFVFTLGVRYLLIAKITFGSAETLHRSLLKSIIRAPLTFFEQNPVGRILNRFGKDISDIDILLLDCFSDVLYCGACLVTSIGIIIYISPYIAIPFVILIAINYIFQLFYNYSVLELKRIQSISRSPVYSLLSEVYNGLTTIRSFGQQERFFNMMKDNININLRVFFYNFAVSRWIGIRVEFLSAIVVLMSALFSIFNDNPGLSALGVTTALGITFNLNWFMRQFGELESRINSVERVQSYISIPKEKETNEDEFIQTGFIWPSRGEIEFKNVEIRYRPNSIATLRNFSMKINAQERIGIIGRSGSGKSTIGMSLFRMIECSSGSILIDGDDISQIDLKRLRSSIGIVPQDPFIFSGSIRLNLDPFDQFTDNEIWEALSKVKLKKMVSTMPMKLESLVQGGDGLTIGNKQLLCLCRAILRNSKIVLFDEATNSIDFQTTRLIKQTIEENFKDCTILTIAHNIDTILDSDKIAIIDEGELIEFDTPLNLIKDSTSRFSKLIKLNNNQKNKLN", "length": 1436 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54VG9-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKSIIILSFILSIISFSNGTIVKCTSASCSSLNNNCVNHYCNPRAGCYGIDKCVRIDACHIVSCDLNNGSCINTKANCDDGDPCTDDFCHNGYGCFSLPNNKHPSVICQKNCNDNNPCTDDFCDFTNTCQHTLKNCEDNDFCTIDSCGPNGCVHTNISCDDNDPCTSDFCSIMYGCYHEQIECSIKVPCSTDIECNRYNLCETYTCDLISNICKYSTKFCNGFPCINNECMTGVIYN", "length": 237 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WA9-1", "protein_name": "Short-chain dehydrogenase/reductase family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKKNIFFITGCSGIGFGGLMVKKLLSRGDYVAATSRNKNKLIQDIGSNENDQFLPIEMNLADESNVKEAIEKCIEKFGRIDILISNAAMGILAPLEETTDKDARTLFDINFFGPLNLIRNSLPYLRNNQFLKNNNDNNNSKLNGPRIIIIDSICGYSSLFNGCSIYCSSKFALHAISETMSIELKPFNIHCCNIAPGYFQTSFLSSCLIPDTRIAEYKDTHSFLDEIVKLNGSRFLGDLSKAVDVIIEISLSYSPPNHVLVGSDAFELFDLKYKKLTNDILINKEICSNTDKN", "length": 295 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WC3-1", "protein_name": "Cln5-like protein 2", "gene_name": "cln5lb", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIFIIICLGIVDKTISSDFKSYNDGIYSFTYDNICSFKNSIRDQDVYELYYVQAPLLYATYGNLLEKINAYHSGIVLYNKNNGPNITIDYYAIPSFEATLFPKSIIKDSQGNYNITWDTHGLIEVTNYINETYWNKRQLIMYDLSGIQIKQYLSWAPIYNKTHTFYNLFNIESDLSISNSSKIYKNSSTCDDFVWASFDVLYKLGGTIASVQSDPQRDDIKLFISSGEPKIVDYNDSIKRNQIASFFNELKDFANLGKNKTALEIFNELITFFNGYFYCYIDGEYYEMKLSKQNPISFTYLPSPIPIGKRNFNEIKKLGFCK", "length": 325 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WW7-1", "protein_name": "Probable serine/threonine-protein kinase DDB_G0279405", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGCIFTKPSPEQQKFDGEDYECENKKNLNLISYIRNLLFGNNSHQQLYNEIIPTTTSTTSTTTNSVYQNIGLDGYNNNNNNNNNNNNNNNIMNNYGYDDYGYSYEEDEDYYDEMPIPTIVAQPQPQPQPQPQPQPQPQQPIRIVSQNQQIPTTPPQQISQFNITGNKSPSSIGSRHRSKPKETLRAHKKRHKDGHKMVNEYVFVRKLGKGTFGKVKLAYHHDTHHLYAIKIFNKIRLKKQTMGIGRPNAFDDVLKEIAIMKKMNHINVVKLYEVINDPQEEYIYIVMEYIEGGSIMSANETSEDLARKYFRDIVFGLEYLHEQKVIHKDLKPENLLVNSEGVVKITDFGVSHIFDDDDVVRCSRGSPAFLAPELCRNESQPISGKGVDVWALGVSLYCLIFARTPFISKTNSLLDIYDQIVNHEPTYPREISNDLMDLFKRLLDKNPLTRIQIAEIKSHKWTTISGTWPMNELDHLILSVTDQEMIDAISTDHTIKPSDNTTTDEDDSDLSSSSGGESSGIIGSSNESKSMYNNVNSKQKIQNQNQNQNQNQNQNQNQNQNQNHNQNQNQNQNQNNNNNSLIEKSNISIPASSSSISNNDSCYENRNVYIKDEEMNMICNDSVIMDPIKELNKIDGLNYGCDFQIGKEYSDFQYNSGHFIYDLVDENESQISRESANDYYLPFKTNKYLNNKSIV", "length": 695 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54WX7-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MARTDNVQLPLENTSIEFEEEIIDSQNDISQQKNYQDFLKNIPTDLNERKEYISSLKKLIKLEKRNHQQIQGEQPNQQEGLNSDRPPPNHHGDHHHSLPPPNHHGDHHHHSQPPPNHHGDHHHHSPPPPHHHGGHHHCPPPHHGGHHHCPPPPPHHHGGHHHHCPPPPHHHGGHHHHCPPPPPPHHHSHHHHCPPPPPPHHHGGHHHHTPPHPPPHHHGGHHHHCPPSPHHHGGHHHHSPPPPPPHHHGGHHHHCPPPPHDGNEYLPQSQTNIEQCICRLNRKKELLIAKIQSIDSIIYNLECLNKQNYQNNYLPSIQLQPTQQPQQPQQTSIKPQQMCQQFFIPQTPNFPQMNNSAPLMYVSQIPVQQSFNNN", "length": 374 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54Y59-1", "protein_name": "Small GTPase", "gene_name": "rsmH", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNIFLSKSKDVYRVTSHKKEVKICVLGDANVGKTNFINQFTKSSFNEEYTPTIESRQNKLYKFNRKQFQIQIYDTAGSKELNLFVSDSISQCEGFIIVFSLNDRNSILKIQHYKTLIKNIFKDVEMPIVLVGTKMDLKKEITISKNECKITSVNNNIPNLFYTSAKNKESIIPVFKKLVDLIISKEKKVKKETESNNIKINNQNKIKKQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHVFKTRSNSTLRMKKYLKLF", "length": 272 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YJ4-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKKVYQDEEFSFFEIGGKKIADLYVRDIITEIRKRGKEITGLGLKSKYELLCILVNRMKEENPSLNIPPKKRVLDFGSLSSTTSNGILQDSNKFFKKDNTHQHQQQQQQQQQQQQQQQQQQQQQQQQHSNNSDDDDDTHNYNDDSDESDDEYIITEEEEIELHKNLNLGDDENLLTLEIKLLESQLENKKFRKSLLLKDKKIKHLENIIQQQQQQLLEQQHQQQQQQQQQQQQQQQQQQRQEEEQQKEQQQKEEQEQEQSSLKNNLKFKDGANLFSIESISNLYNKILNEFNFKKIITEFGDSSLKIHEEFVKFIILKSINLNHNNNKNNNKNNNNNNNNNNNNNNNNNNNNNNNNNNNSSNNLPNGDVNKNNNNNGEIIELVPPPKIDEFWKLMVLDTVGYQQFSNILGAKVNYDTDINPTRKGYQRLKDMKNLYFPPPPSTTELTTDEIWPNHYLLPIQPSPQKQHIQKQQLPSSSSSSSSSSSSSSSSQQHQQHQPQHKQQHQLQQIQEQQPQQQQHQQQQHQQPLQQQIQQQQQQQQQHQPQQQHQPQQQQQQQQPQQQQQQQQQQQQQQQQQQQQQQQQKKQQQQHQQQKNKENNKENNKENNKQNNKENNKLNDNNLNIEVHEDEGNRIINFLISPDTPLRNLFVAYAKEIGENFNSFKFYFGNELLCQNETPSQLLMRNGTKIQAFYLNKKEIKK", "length": 702 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54YV1-1", "protein_name": "Rho GTPase-activating protein gacII", "gene_name": "gacII", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MVRKLFNTSHKKELILDVDTTIVKIGTPKNVVLLTKWLDANGAIKEEGVFRVNGNTTTMEQIKKNFSQGKDDLTKYTSADIHSMAGCLKFILRELPEPIFTWDFYPIFIKIQCLQDESRKLFFLKMLIHGLPYTSRTLVFQLFGFLSKFSVHQDQNKMTPKNLATVFAPNVLRPKKEEDNFQLMNNQDSIGVIETLIEEFQYISNIQKNTLNSQEIKVKSVLPFDETTNAITQQSLVEDYLIAKANTPQESSSFKKNLPFKKGDIIKLLYIKNDGNFIGEINGITGNLSQTYVDIIDISELAEAFTLTPPPIPTLPIASTILHTPPTSSSSSSSSSSSSILLTDNQPKLCSSTPRINNSPSSFSPSLSSTTPQLLVQQSPRQSPRQIPSISLIVEPNNTNQPSFGHGTLQRTSTGYFSSKPLSISQPINMSKPTNMSPPTHHAMSMHNLPPSNTTRENHLPPLPTKPPPLTIPSSSSLPTTPIKQQPQQPIQQPLTPQNHHHHHHHNNLSSSVNTANTGNCANILSPNSDRYLSSRSQSSVHLSGSSSSSSSSSSSSSSSSSSSSSTSNRKFDFSLKSKSSKNSPSKNLPPQPTTTSTLTPPPPPTITTTTTTTTTTTTTTIATTPPPPSKPLPNIPVKDQQFNTLKRSTIEIPPPTITSTNINNNNNTINPRTLNYSFSSFSITYNNSQLGGQLSQEEPPGGVKSQSSYLDNNNLPSRNTNIPNLPPRPPPLNIPQQQQQYKPLPSPPQLQSPQSSLNQSLQIPLQQQQQVQQQKLTTHYILPPQNTNLSGKNLQRSSTSMLLNKLPPPPFSFNKN", "length": 817 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA1-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNLNITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSGSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZA6-1", "protein_name": "Alpha/beta hydrolase fold-1 domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKINQTPKKHKIIEPNRKGYSIVGKNTGKPNKIYFETFGNGPKKILFITGFLSSSKGWCKQIDYFTNKKDQYEICVFDNRGIGKSNIDSKYSYNFSTKSMAMDAIDLLEDTLKWDKVHICGLSMGGMASIHLSSIIPEKVQSLVIACVPNGYFLPFFSMGVFNYIRAFFFTFNEKKKARIFQSLMYSDNYLDEKTNGSDETRSEQMFKKNSTGFKDDGPSFLTILGHQIGYITNRFSKKSLEVIKKYSIPTIVINSKKDSLVTIDITKKQIVNPLKPLNFHVIEGGHLSQLENPTFFNKLVENHVDKHSNWDHSTFFQVEKQQFQRQSFMTQNILYSKNYLSSNTLSSSFLNCNTLRSFFNKIKV", "length": 366 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q54ZT3-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551H6-1", "protein_name": "t-SNARE coiled-coil homology domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MATRDITSSYILSRTECKNRAKIINSAININIKKSGSGYKRLEEENYQDIDIDNNNNNNNINNNNINNNDNDNDTTNNIKNSNNNNDIQLNILDTEINIEQLNSLPPWILKLNDIDENIKKIISLIEKFKKYLKEDIDKILAEDIEMESRIDCERSIELLTMETIRLFHKTFDMIKYLNKSNNSSQGENKMKKNTQRMKSAKLKALLITFKHIQRSYLALLKKVSSLQRSLSSSFLYRSGEYDVNNDNEDYGENSSISNSHYLQHHHNNNHHHEDDHDHEEDHEEIMDELNEMATTLIERQRVSQLIKETSHLIQDVGSMCVKKDSIFDRIDYNLAEGEELEFNGTILICDGITNGYERPENEKRKKLLLIFAVLIIVILFIFILKYVIEI", "length": 391 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q551V5-1", "protein_name": "EGF-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKYLFRFFIFLFCITRINSQTGCFFRETGADYNIDSVFSVFYVDNLFNIFGMTFYMKTCTYVTCDPWRQTMICGNYNSTTFQLGPYQSQKVTLNKNGISIEYLSDKTPPNHPCPTITTTVKFICDKSVLSVPKSDYDYVGTCGVQIKLFAIDYCQTCSKCIASHGSCNSTSGWCTCDSYTMGLNCDQLKASISSVVAPTIDGGSVIISGDFSSIYSLGPSLVITIGSLVCSQVSFAASTTQISCTIGAGQGYQNLTISDGSGSTLQYKQFYYHYPCQEDCTPYGTCNDVIGKCTCNYKYSIGADCKTLNLQLTSVKPTLLDGGQAYLVGDFSNVTGLTLSVKIGIKECTDVNFNETTLQCTIGSGEGIKDIIITSDLLTYSKIGAYEYQYYTCPLGCLHGTCNKYNGLCVCNNGTYGDQCQYIECPLDCSTPNGVCDKDTGICDCDDKYSGEGCDFIKCPLDCSTPNGVCDGKTGICNCDEKHSGDSCQFLQCPLNCSNPNGICNRNTGICSCDSKYSGEGCDFIKCPTDCSTPNGTCDGKTGTCKCNNPYTGENCDEIAKCKQECSLKHGTCDSHTLDCICDTQTKGLSCEESRLLIESADPTSLDGGTTTITGYFGTTTSLLSIKIGDSQCTNIKVESDTKLKCDIGPGEGTHNVTVTDDDLSFTGVGMFQYVGQINKISKISGGAIAGIAAGCVVGVSVLGAGGYYQYRKNKKIELFMS", "length": 722 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q554Y8-1", "protein_name": "ADP-ribosylation factor-related", "gene_name": "arrB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGMGFSFIEKKDFKRFLILGIDNSGKKKIMYRLKFNKDIPTRPEKGFFVETFERRFKYNNEDVCGQNMIRPLWPNYYTDETNGLIFVVDSSDQERIEEVRLEIKKLDENIKIFKNHPFLIFANKQDLKNSLSIEQLIDKLELNKLSLNRKWHIQSSNAITGDGLEFGLNWLFSSSHNFT", "length": 179 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555E8-1", "protein_name": "Putative fatty acid elongase DDB_G0274669", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METVQSIITEWTDPKSWEKLVQHSFKDSNWKELIDPVNYKFNFGVTPFSQFQIIPIVLVIYLVTIFSIKFLMKNRKPFSLKFISILHNAILCIWSLIMCVGVLYEIIKRVSNEGPLFTVCEDPNGGFDKGVTYYWSYIFYISKFYELLDTVIIVLKKKPLIFLHVYHHCKTVWWKKYITMIQILQFVCLGIAGVLHVYTINTIGCFTHYPAFAAAYSINFSFLFLFSKFFVKSYTPKNSNSNTNIKSKKID", "length": 251 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q555Q5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MRSIRIKKINFHIKQGEEQLKQELNNYCEETSLKYISARIKKRHNDFTINAVKDAQGRTINKQELIEEEYVKYYSNLYDYKEDDAPSHYEMLENWTVTRDSTWDNLENEFTTQEILEVIKQLNPHKSPGPDGIPNLFYITHKEKLAPILASAFNDTLRNPHLISKNYKEGLIITIPKKGDPELIKNRRPITLANCIYKIHSKLINNRIIPILTKVINHNQKGFVPGRFIIDNIISMNELINYCNDKRINGIITLYDFEKAFDSISHGSILRSLQHINIPTNIINLIMNLLTKSEARIEINGRTTIPFEIKRGVKQGDPLSPTLFVLVIEALARKILQDDRITGLPLNNSDHREKFQSFADDSASMVPDSQQLELVLQHFNSFCKATSSKLNIDKSSSILIGNPDNTNQRIPISTNPERYLGYFFTGKGITRKIPEILNTIRSSLVLWKTTDSTIKTKTNILKAFALSKLTYYSYVENFKEEELNQINKLVEWFLSAPNTKMLVDFKITPKLSPTAKKDQEVNADYANHRFHKEYFEWNYKAIDYDLTRSFAYRNLMALILHNIWIWICNQIYSEDPLTDESLSYSSLLKKWHKLATLEYIKKAKDLKNLSAKDHNNFKDPKILLTSTIKLRKTTANYYCIPESSLPNIISFDQFI", "length": 655 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556H5-1", "protein_name": "Cofilin-3", "gene_name": "cofD-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTTPKPTIAKISPECQTHFQDIKFRNKYQGILLKVNEESNMVVDKTLVAEGEFSELAQSLPTDQCRIIIYRYKSGEGSKLFFIYWGPDSAPQQDKLIYGNAKVTLAITLKGIDHKISASNLKEISEQVFIDRITPKTA", "length": 138 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556J5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWNHNLCHAINLDRQFDHINNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNKNNNNNSYDYSFSVHSSQQYSRHYPNSCNNEQTKPKDYYDHASRSQHDYHANGSNNGNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNNNNCDSNYNSNNNNSNNISIANIKYQQDQHYQHSDTYTSHQYNSFNDNNNNNNNNNNNNNNNNNINNDNDNNGYNQYDESEEDEEEQDDYDEFDIQDSASSYNDNCGVLNSNTYIYDYQSPQQPLYSNEYQNNNHQPQQTDSYNYNNTNNDNNSYNINNNNNNNSYNNNNNYNNSNNNNNIGNIDSNTNNNNYNYNYSNNGDVYNGYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNMNNMNNMNNNIITSNREQFYSNNNHNNINQYQYQSQQQQTQQQQQQTQQQQQQTQQQQQTQQQQTQQQQQYLTQYYQQELYSQSYKCRPYYQNSFVISKC", "length": 480 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556P1-1", "protein_name": "CWH43-like N-terminal domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MISSSLKPSVLLWILAILIPSTLITTYTLTVLLFHGIRRTVPYISDTIDFSPESCIGTFFISISAFLVFIVVFVKHFLLQNNINQNFNIDIILNENENEKKKNRAKMLNRISTFLGLICGVCIHGVSSFQYHNTGLVHSIFAASFFFTGFIYIFTQTYLDHKFSKLPKRILILRRVISLTTSVFIGYIILQFFIDNLAPILKIISALSIFFYLISFFYEFSKITINFQINTISQIEHQKEYNENSALLISQ", "length": 251 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556R5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFNFERIDHGSGKGTGIAIENRDTRKGHISINFKDDDGRILSIKYNSFNSINILLINAPATISERNTFIINSKSLFKKYNSINHQIIAGDFNNNHDCNSFFGTELRKIIDQDMLLDTGIEENTPTFPRSMKRLDRIYCHPTLLNQNSKLVVHNTVFNKSDHFPITITIQTNRETTTTTTTTKLERLPWTLCKEILNNKHIHDGLSELISKNKDKIKSVEEWTKFKNNVIRDYLKKEQNKIKKEKNKRKYVIHKLLGNSDIIPKMRKELNEEISRILEEERKVKAWDIKLKLHLHQETPSKYLTSILKSRAKDKSIFQIKDKDNKTISDKENIAKRFVEFYQDQYEEKEDNEETHKKLLEKWEVDVDLIKKLEIDRPIRIHEVTKAIKTSSIHKSPGLDGINALFYKYHINSIARILTIAFNDLLTNKKEIPTKFKEGVITTIFKKGDELNISNRRPITLLNTDYKILSKILNSRLLDITSKIINKFQNGFVPNRFIQDNIQIMKEVIEISNKRKNNTLITFYDFNKAFDSISHKSITRTLEHIGIPPKFTAILLNLLKDTKNKIKINDFLVNGITIRTGTKQGDPISPTIFALVLEPLLIDIINDNTIKGFTLPNSKSLKLTAFADDIATFTNSTEELMKINTKIQKYCSATSSSLNKEKTVMIAIGDKPHDLPFQESTVPERYLGLNFTKTGLNSKYNTLIQEMKNNLIKWKSQAITMKAKMTILKTYVLSKLTYHQYMDNLNEEQIEEINNMTRWFLFSSVKNTYTEERKYKTMMKIDRAYADWKEGGIKLWDIELRHIAFKIWYMNRLLHNNYNNNNNTLQEWYMEQLSRKKPTLQPSTICADTGVYSESNFTKTIQR", "length": 861 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q556X2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557C9-1", "protein_name": "Homeobox protein 5", "gene_name": "hbx5-2", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "METIVNNQNNGQQNTVPTQSFSSSVYMNYDFFDSQQLQQPQHQPQHYQQQDSFVSPNLDNNNPQIHVQSNNYNQNGFVGYNNSNNNNNNNQHMNNQYSNSFHNNNSSGFMAFQNNSSNFNNQNNNNSNNNNNNNNINSYDYNNSNNNNYNNNNNTHSNNSNNNNNNNNSNYWNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNNNNNNHHHHHHQQQSQPTSPYNNPIQHNPNDMKFNGQHNPFNGNQMVMDNNNNNNNNNNSNVFNSNSNSNVFNSNSGSFLQINNNNGSFSSYNNNNNNNNNNNSNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNNNNNQFSQSYDSTLGNNRFSSMMGQPIQQQQSPPQQQQQQSFIQSSPQAIPASNCNGNGSTSSSTSPLSPTLIGSAPGTPTSMLATTLFGFNLSSSPTSSPSSPVKKGKSQSALALSSSGGSGGSSGRKKPQKHDSMSSITNTNLKSTQASTLKESKRSNSSPNLKKQMQLQQLQQQQKLNENGTLIPPLPFASISENITNNNNNNNNNNNNNNNNNNNNNITNNPLSGSMEFPNSNNINQSSDSINGEFNIGQPESPKMYNSSPSPPPNATSTTKGGKKSKKSLHISTTQQSPSLNGSTGGSMLTPTMSGLSLSGGGSGGGFSPLISPTGTTSNKDLQSSPSPSPLLKSMSMGKLDLQDSIDSMSSPLSPNSSLSSSNGLLPPPPNSNNMNSSGGIPTPSTPTSPPPLTHHINIFSNLEFVKQLKDHLLPNDFKPEEHALERNLLRFQQFVKTLAEPLQRDVVTSMFELSVDAQLQYGSNLDNDNLSALMLFRRKILNFNLFRMMMLNDPNSFIPLPSPFPIQTTTISSNGTIVNPTNVNNNNINNNNNNNNNNNNNNNNNNNNNNNNNNNNTTTTTTTTTSANTVQSGTTSNSNLVFQQTSNSNTLSPSQQQQQQTQQQQSINGSSTGSLSDAQYQDLGIHLDTSSANSGCGINVSIGSSIGGGGGGSSLNGSNLNGSSSISGSISGGSSNGGGQFIMSPQFSLDGAYQQQQPSSYNINNEMELAEKDEDEIFNNNNKDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSSSINSNINNVNNCNINNNSNSNNGSINSPRPSTPTTLNSSGKRSKKIYRGDSFGAGNDISTGLMASSDQIIPPPQQQQHQQLVNNNNNNMNNSENNILLADSNKGLSVSLGSLPTNTPSSMEIEQQQQQQQQQQQQQQQQHLNQQQILHQQLHHHLSSSLGGAQFTNIQQQQQQQSGNIFYNSPYNSSQVYMNPYGTSITNTSLAGPSTTSSAMQHMITNMTSSNIIVNNQNNNNNDQNNNNNNNNNNNSTTNSNVNNNNNTTNTPSSPPQPNNCTPTQTSIITSNGVVVPSLQMRGTITNPPPVLPTPDTLVLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQETPHTPTSNSISSPRSSPVHQQSPSNTNTTTTSTTTIRHSAVTQLSFAGLHNQQVSPISPRSPRSPHGTSGDYNDGSQSPSSRRKNRFTDFQIKRMNDCFENLDKNNNGKFTSEEICQIATELGLTDQQVRVFFQNKRARSRPSPRGQPTNPLTSSTNNGNNSNLALQHLQQQHLQQVQQQQQQLLQLQQQQQQQQQQLHQQSANTTPQLNSMNPNSINYNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNIINNNITTINE", "length": 1723 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q557D0-1", "protein_name": "RING-type domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTGSNNLNSLNNNNNNKISLQETIQDIIKCSICLNSPKNPRFCPRCSALFCLECIDRWIISNPTCPACRDTLTSDNLNSNLIVSNILNELVKSEQEEYTSSDICNYHGYERLYYCSTCQEPICSDCALFKHKDHKIEKLSINFNKNLEILKIEEEALKKRQEELIELNSFLELDAETLLKNKSQIEKEISKVVITMKARLKYDFERRYNTILESQEKINNELTHLDFIYNDLLNHYKKSPSSFVLTSQQFIGVLQSVHKNSIMDIYTPINTDLTSELIPPFENRLLKFENFTTGDCLFSSRIAFYGMTWEIKCGIEEDNCFLNLKVLECNSDGKYFYMFTIVNQKTNVNKLIEFDLPFQAGETFYIPNFSSKQTLIDEGFILPENDILLLQFSFRPQNYFCYSNDLKRYIDILEYRHRGYFGEEDEDDGTIETTVTKLPNDKSTILGSDNYNDNYNDDGIGDLDEDEEEEEDDEDDDDNLDDHLQYDNDDDEDEEEDDEEQNEEDNDEEGTNIPTSEYEDLDTSSASVISNINRRDRFKNNNINNNNQFVNSNNNNNKYNTTNSNNSIVGSSRYINNNNNNNNNNNNNNNNNNNNNNNNNNNNNYILNRSYSTNKIYNFYQDEEEEEEDDDSNIDDQDEDEEEEDSEEESSLSSSDLQDLDSSGDQSSLEFSFSKYTNNYYSNNNNNYNSGGGGGVGGAGDNNKIECIRRDFNNLLKRINFTNSQLTNLKPGVPKDGDLLNDDENDKKCNIPLNEDEEEDEDEEDDVNKNKTTSTTTTTTTATTTNEVVTINPNTISNNSQDEEEVKSDIVKLLENGIANMLNNSNSSNRSSNNLKQQQQQQQQLQKDDQKQKDEQQNKSNTGCDIDQLNILSKLSIKESCDSIKNNDNDSLGNSTNNNNNNNLNNNNNNNNNNNNNNNNNNNNNNSNNNNLQSFLQSNENTENETDFNDNNTNPETNTETENEYLTSSNMNLDGGESEFDSNKSYEGSSTDENFNSDEDYQDEDNFNQDATGSESANNDDYLDDNEREGSDSIENYDEDIEKVLTSHNIITTPSIPPSQQPQPQLQTQPQTQPQSQPQSQPQLQPQSQPQPQTQPQLQPQLQPQLQPQLQPQLQPQLQPQLQPQTQPQQQKKYDDLSENQIQTENRNKKIKEEINNKTNNDNNNELGKSSKSNTSSSSSSSSSSSSSYSESESSESDSNNEYDNEDEDDIVNQVSNFNFNFNDASNFKNFSFRPKFPSDENDNDDNDDDYEINIDLKNIQKISPILRAIENGESNINHYQSPVSLSSSSSVSSFSGSGNSVPITATTTTTTTTTTTTTTTTDDDSGINMPISPLSASPPSPPPQNEPQINNETNDNDVKLPQI", "length": 1364 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559A9-1", "protein_name": "Probable polyketide synthase 13", "gene_name": "pks13", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENFKYRNNENDVAIIGIGFRLPGCKNFTPNELWNNLKNGFNGVVELSNRWSDNFYTMGKVSSAYAGLLPFDELKSFDPLFFGINPTEVPTIDPQQRILLKCTWEAFEDAGIDPIKIRGSNTSVFIGTSTNDYQRIIREKDQTITNAFGTSLHATSNRISYCFDFRGPSMTLDTACSSSLNCVKLGYQSIRDGTSNLSIAGGVNLIIDPYFTASISDLNILSKTGSCKTFDASADGFARAEGSGIIVMKNLKQAMIDGDKIYCVIKGASSNVDGGGLQDKSNFYAPSSLSQCNNIKMALKSTNGTVEPKDISYFECHGTGTPTGDPIETRGISMVFNDESRSKENPLLIGSIKSNIGHLEAGSGIASLIKCCLMFKNKCFAPNINFKVPNPKIKFEEWNLKVVTEPIQFTKSNTCIGLSNFGVTGSNCCLILSQFNNNNNDNQIVGNNNNIKSNKEYLIPFSSNSVKSLENYQQLLIKNGENEFKFLEFIKHQIFTKPTSLYQRSVVIASSWDQFNNAKIMKTSNSKSSNISIERNNPITVFVFCGQGSQYDRMGLELYNNDFIFKESMDLLDNKLSKYYGYSVLEKLRNCDSKSIQHPMIAQPVMCMFNISLFELYKHWGIEVSFIIGHSLGEIPAAYCSGMINIDTLCYLIYHRSIAQTKTHTNGRMLSINISADEYFSQYSKQYPDIEIACFNSPTSIVIAGNEQKLNEISEILKEKGIFSAMLASLSSFHTSSQNKVKEDIVNKQFDSKQSEIPIFSTVTTNLFDSVTSPFNSSYVFNNIVSPVKFSQTISNLYKHIESNQLGNDIVFIELAPHPTLQFYLKQMIPKPTNDDNSIEFKVSVYSALNKKNNDIEEIQRTISQLYCDNGYNVNFKCQFQHDDTHGSINSNINQLSNISLPHYQWDDEKYWKEDPSISKLIVNGPQTDNLGYLNENSPNSKSYETFIDIKRPPFQYLKGHMVKGKYYFPGCGYIDNLLKIYKSQDLTINQMGFKSPLIFIEGVNQALQTNIFKKSTSNTTTNNNDEFRVEYHFNDQKTNRWILSSFGDFQLSNHSSNSDNLEKINIKQLIQNQCNLTKLSRDELYSHIKSKTGLTYNGVFQGVNKCYLGENCSLSEVSLELKREPSSFFNTAVLDTCLHGMLCLLEEQSQLVFDRIEGFKYHSSNVPTSEEEMKIHSNIYVYSTINPSRIGDSYSASIVIMMEDGTVLIEIENAVCTSLTPIKESISVKYPTNQLFSMYLQSKDSPIPSPLNFKSLYNQNQQQLKIDKQFTDWMQKCEKFISNQFFKNIEKRNPEINLEILNSKTIIELKSKYCQNLKNERLFQFVFETIKQLGVNAYDDDDDLTIDSSEDRKSIYEILIKSTKVIPKLLFPLEDEDLTIDSPQSLFENGLLDRFYNNPNLMTNQCQLIAQIIKESLKPLLNKKMVFRILEMGGGTCSLSVVVLNLINQLLLENPSFEIDIEYTWSDISPSFISAAKEKLSHIDKRINILYRSIDIEQPFIEKQDLSPSYYDFVIMSNVLHVVKKLSPSLDEIHKILTPNGHLLFVEIPYKELISDSIFGAFNQWWAFEDTDIRKDRCSIPPNQWIQVLSNHNYKDTIVSDNKECTWCCFVIHSQKPSLLELSKKIECNQYDNIIVFGNENSQDNFTKSIKLSYNNNIIKWVSNIVEIKKFIKLNIITNNSIIYFTKGIEELTIDNFKLINFQYIQINQLLLKYESKCKNVLVTRDCDGSNYLASSLIGAARYFDEYRQLELFTLDFDNDTIQSCDECSSSSCSNLIKLIEPLIDPKINIQREFLIRNNRVYFERAKLETNLKKSFKSESFENSNKLISTLNFNLDYQLQSKPFKQLLQNEIEVEIKATGINYRDYLVFTGSLPIEKTNHNGISNQPEFGVDFSGIVTKVGGGGGNGEFKVGDRVYGIGHNTTSSHITIDSRYASLIPNSLDYIEASSITSSYILSLYGIFDIGNLDIQDNESILIHSGTGGIGLSALNSLRWKGHKSHLFVTVSSKEKEQYLRDNYGSFITGIYSNKDKNYPKLIKEKLNQLGSNKQGVDLILSSLPNGDDNLNFKCLAKNGRIIDLSNNIDLFNISKSKIKKLLNTINDGFESGELQVIPIIEFSNSNIRDAIEFINERQHIGKIVISHDDSNLLIDLINKHSNQPNYSILKSDYQISQSNLGKNILITGQSGIVLEILKWIIKFSNSIENVIILSKSLMKWELELLIGKTMKKANNKIKFHFKSVDVSDSIQVENSINQILNDNPNIVNIDSIFHFAFTQITKKVEEIDMESLNVSHNAKTIGAINLHNQSINRNWRLNNFVMASSATSIIGSTDQCSYVCANTVLDSLSKYRKSIGLPSICTNYGAIESAGFVSKNESVAAMFNGIGIISISTDLILGTLDLQIQNQQSSTNLMLSDFNFLNFVNNNLQLSLISKFDFQTNLAKNQVNEKLQNQTQNQNLQIQSPSSTTDCQTIIKDSFLHKISEVLSIDISKLNLDLKLLDYGADSLAIVQIKNWIDMEVSPNLIVIQQLQTFTITSSIQYTINSFLKKKVQSQE", "length": 2551 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559I8-1", "protein_name": "Uncharacterized protein DDB_G0272530", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKIKLILVLIVFLTIVNVNNSIDLCLSNPKKALVNQACKYSTDCEYPLFCGSGNGYGKNATCSKNIETGGSCESNNQCTPCNVCFNAKCKVKLYLGDACDENKSYCSSSVCIKGKCSIQGDVCTANNQCKFNNYCKSGKCVPLEKEGSSCDKDSSCSLTNACVGGKCVTKYQKPLGAVCNSSNECQVFSGHVCGANGKCSVYNQLLSKCKENSDCGPNGMCMCKSETENVCVDLSVGALKNDKCPSLLSSFSSCMTRERCTENTPTGCPKCYPIFMCYQYSCFYMNQFIRSTQNYYKSFCS", "length": 301 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q559Z2-1", "protein_name": "E2F/DP family winged-helix DNA-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNISLLLNNRNRNRNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNNGNANESASLNNGSEEIRSNPSSNFSSPIQSSLSSSSSSLSSNQATTPKKRSHAHKNSLKCQSPQMSPQMSPQMSPQMSPPLQYFPQHQMQHLSQYQLDHLQQQQQLIQQEQQEKQQQQQQHQHQQQQQEQQKQQQKQQQRLSPQPRSSQPRSSPPRSSPQRSPQLNQQEGHINSVQTYSGNNINDKNQNNTNNNNNNMSNNNNFHDDNNCNVNYNNIRNNSNNNNNNNTNNNNNNNNNNNNNNNNNNNNINNNNNNNNNSNNNNWNNNYCNNSFADETNKNNTYGMEYINISEENQYNNNNNNNNSNNNNNYNNYNNYNNNNNNNNNNNNSNNSNSNNNNNNNNNNNNNNNNNRNNIINSNINNSNNNNYNDNGYNNNSNINSNDSYNNNNNNNNNFNNNNFNNNNNNNNNNNNNNNNNNNNNKNNNNSNSYNNNNNNYNNNNNNFHNNNNNSAHNNNNNNYNNNNNNNYYNSNNNNNFHNNNNNNNNNGNNFNNNNNNNGNNGNMFTNVNSIDNVNRNNYNNYNGNNNYNGNNSNNNNNSNNEVSQITTTSLPVKKTKVFKAPREKKFKRGPDQDIREIKPATALLKQYFIGNSITEFNAERVGSILKINHEKLKDILDIMECASLVINNHSNNYVWLGLDNPGFLKLVFNVFHCSSNLVTKEPEFACLKCKENAYRCPTSVDLPKDTRLGSTVCQFMKLLLSKRIRTNPVNDFLTIYQVCFNFNFCSEGRCPEEDFKYLRNTAKVKRCYDVANVFNGLNILEKVGKSKIHSYQWCGDFTIQDCENGCPFGHPLLTPGTAYTTNPSPNPFNQFSNAYISSSAQSSLSNSPFIQGGFHGNNNNSNNNNINGNNINGNNNYGYNNNNNYNNYNSNNSNGFNNGNSFFQQQQPLVNSGVSMVRNNNYSYSP", "length": 964 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55A39-1", "protein_name": "Transcription initiation factor TFIID subunit", "gene_name": "taf9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSSNETLPNSEQENNSKTDTKNDNKNIGDENKIIDTDKDMKDNDTINGKENGNININSNNNNNNNIDTDKEMKETSSIEEDDNNNNKNQNNNNNNNIKEENDNLTELKNNNNKENKENKEETIKEDKEKENNKEPVKNKEETNNINNNNNKNNNSDNINNNNNNNSKETLNKISSMSKVSLTSESSEINGQVNTGVVNNNTNIDITQTNLDEPRDSRVIKSILKTMGIQAHEPRVVNQLLEFMYKYVFEVLQDAMIYGEHSGKTDIDVSDVRLSIQSRVNYQISTPPPRELLLSIAEEKNKTPLPPIPNRYGVFLPPDEYCLTNPNYQANPTKPVFQPVQPLVGNTSRGNYNKKQSDKQVSIKFNSMSNNSTTTTTTTPPTIGSQNGTTIVSPPNLGSLGTTTTTTTTTITPPPPILPLSSNIKPPTLSIPSSITSPPTVTTKNTSTPIIGLGSTTVAPPKTSSSSSTIAPPVLSLPTSITSPPTVTASSTTTTTTAPTTTSPTIPSLSSPTTAATTITVKKEDVKMDDFDDFDGQMKDDITPSSTPQQPSQPTESETTTTATATTTPAVTTTTIPPTTTSTTPPTTATTSTTPPPSTTTTSTPPTTSTTPPPQIKEEK", "length": 619 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55B17-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MYKKILLIFALFILVNINFASSEFKKNETESANLKSLYASYLMKNNNNTKYNNNDNSNNTNIYNDSVTKNKSKNKNELTVGIIGGGIAGLYAGMLFIKSMIFDDLGIDYTILEANKERVGGRVYTHKFDDHKYSYTDLGAMRIPLTPLMDRIVSNQNYSLFSKLAKGGYQIPTVPFLISVNNEISYYNGIRVLKGSPVLNPSDPFNYSDSNNGGPGKGIPDEYANRTVDSLILPVFYQFINNLTVDFYNGFKQMLKYDSYSARDYLKTFHNYPNSVIEYIENLSTISGRLDQTSITELLMSVFDFSGEKFVCVEGGTGLIVKSMSQIIKKKVEMGSFVTKISKSFDKKNNEIDGLNVEVVRDSNFGGSDTEILKFKHVISTTTLPALQRIDTSDLKLPLKLKVAIRSLKYTGAIKLAINFKYRWWEDSEFMSGKPIRGGSSNTDLLLRQVVYPSYGINNGTKGVSGVLLASYSGGLESIRISSMIGKKDKERKLLNIVLRDLAEIHNVDLKKLKNLYKDHFFQSWDNDEFSSGAFALFSTSQYTELFPSTGQSHVDGRFHLSGELTSVHHAWMIGGLNSAYRSVDLILKNEGFEDLRIKLRNNWGTIEQAEYPSLDWYKYDSDINHYKLY", "length": 630 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55BT6-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKLLYIVVFLLFAIKLCCSEYCGETYCVENRNCYSFIGCRNSTCLYETIDLDDEVDCTVDTCSDRYGVKNTPNNSLCPPENLCDMFLCDTQSGCVAIPKVNCPAPNPCQIPLGCNRETGICEYDEIDCHDDNECTNDYCDPILGECVHFSNDTICSNKASNFSTCVLSGVCGEFGCKYVEDNCNDGNPCTDDYCDFKNGCVSQKNDWNCDSLSACSEGICTDNGCVQQEVDCDDDNPCSEDFCHPLFGCGSILNDTICTNGNKCVNSTCTEDGCSLPVPIVCQDGNPCSDDTCNPSTGCQFTLNNSNCNDGKKCTIDQCGLNGCTHTNITCPPKRVVDIILIGLICRNHYCDQSTGNCVPDMNSVSLLCI", "length": 370 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55C69-1", "protein_name": "Chromo domain-containing protein", "gene_name": "hcpC", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGKTNKKKIEEESEEEEAGDVFEVEKILDKRVQHGRIQYNIRWKGFSADYDTWEDEANVVGCPELVREFESSRIKEKKKNRKRKNVIIDEDPTEEISSSLSSILSSPQPQPPPPLQLTNHSPASSELAITTNTFLISNCTSTSNKTKISIENEEIIKNDHARYGVPYVEGIGFENGDCVDEIVGCKPFGENNLLYFFIRWRGKEKLSWVSNESIKQKEPLQLIEFYESRLKFGYKGEEN", "length": 239 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH5-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKHEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEGYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKNNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CH7-1", "protein_name": "SsDNA-binding transcriptional regulator", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIFKITRTKRRWTKNQKKILVMKVVEKKVVVKKSKTPNTSPSSSSSSSSSSSSSSSSSSTNDKSFNLSDKRKISYSNFKGLERIDIREFFEDKSGELKPSSKGISLTREQLVVILENGDTIKDWIKESK", "length": 129 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CJ7-1", "protein_name": "diaminopimelate epimerase", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEPSIDNKPSFRINFTKMHGAGNDFVVFEKNKVERLNGDKSTVTFEEIVGFTTKIAHRKLGIGFDQLIVIDDNPIDKNAAYGMDVINCDGNIEVMCGNGVRCFSKYIVDNKVLSKNLKEQLNFDGDDDIEQIIETKSGIVKTYPLLKHHLNNKDNDVIMVKVNMGTPKVSRFINEIDRHIPKVLTNQSPIESYMYTIDIGLPYCSKLECVYVTVGGNQCVVFIDRNIELGYLDSSYGDHTKFSTIDFKEISDIIQSNVNGFDDIPNVEFVIQSPQDKLENKVISRVVERGNGETLACGTGACGVAISSILKGYCNENTEITVEMPGGKLLIQWNPNNEIFKTGPATSVFKSQILI", "length": 355 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55CV8-1", "protein_name": "Lipocalin/cytosolic fatty-acid binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MELLVGGTILGALTYAYSSLKRTIPEGAHACSPFYPEKYVGKWYEIARLDFYYERDMNNVSAEYTLNKDGTISVINSGYNYVEKKRESVNGKALFVHGSDEAMLKVSFFGPFYAGYNVIAIDPDYKYALVAGRSLDYLWILSRETSIPDHIKKQYLELAESIGYNTSKLIWTEHDNINNKKD", "length": 182 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D49-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIKIMTWNCQGCSTIKSMNQTKNTINLIKPDISILTETNLKKDQNLAQIKNHYSTGGKGKEARGKGVMAINHLEQIEIKNLEEKEGRILKFTAILNNMEINIICIYAPASYDRRKGWFSNNISLEDLEQADIVTGDFNINKYAKIKFKDGSSDKRKFTENETIEFLMMEVGLTEILPNSTTKTTFKDKLIDRTFLSTKMHQLNHSYKIIDKINKSDHNIVVMDFKIPNFTKIYKSPLWKMNSIIIKEDKTIKKIEKIIDHYQETKRKNINITEYWIKFKKKIKKQCITTEKKRILERKKTLSNLANEHTKTKNKYEKETISNEITILQEEERIDRMIKSSINYINNKEIASNLLTSILKKRDSSSQIHRIKNPSNGEIETEQKEITDCFRKYYETLFKEKECDQETHTELLSTWNPPIDKKKLTEMEDRIEEYEVKLAIEKIAEGKSPGEDGITSSFYKIHQHKLIPILTELFNFFLNNEIPTEFKNGILTSIYKGKGDVLEISNRRPITLLNVDYKIYSKIINNRILKILPNIISKYQNGFIPGRLLHNNIIALDLAMEKSDRNTIITFYDFEKAFDSISHKALIRTLNHLKFPRKITNTILSMLTNTNIRVMVNGQLSESFRAGRGTKQGDPISPTLFAIVCECLSTSIRKDNTIIGIKLNQNNSMKIGQYADDTVTLASNIDDADKMDMKVIKFCQATAAKINDNKCVCITKNPKIKTKYKTIGAKEEERYLGFFFNRKGVISKVDDTVNKLENLTKCYSSVSSTLKGRITILKSYLLSQLTFQLYINEINDIKKLENVNANMLFKGDRWAISKERSRRDYEIGGLELWNMATRSNAQKAWIYEQYLREKDDQNCPPHMEVWKSEKENSLSRIHIKCWKAWKLLHHPRERITLKLNQVKPKYENKQKLKVIYRNMMDIKYKGWNKHQPTTGQKLIQKNINHPILPFREARSITTIKGRDLAWRYLLKALPKHHGENCHSCKEEESSMHIFFECKSIKQNIDSIYQKVCKDSNNTYHGPWSEKVLGKLLTPFSSNLIGAIMESIWYRRNQIKFNDNTTIITENQIIHKIKKARDAEWDRTRKIVEKQLRQELRCTDNRESINRTASIKRRLEKFSHNWNSKLMTINIPEHFIPYCSYNTNYS", "length": 1144 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55D57-1", "protein_name": "J domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIQVKNKIKIISILITLFILTINQVVECKSSLYYSILNDYEKGIDYYKILNVTKDSTYSEIKKSFRKLSLKHHPDRNVEKSSHSLYILLNQAHSVLTTDETRKEYDELLVNGIPWHENYYGKYAYRYTGISHDLRHVLLGLIIVITIGKFVYQYNKHHSMIKRAKQTDQYKKRLAQLDGDEDEIQLVIQGADKPTISSLFIIQLFFIFPFKILKSIYTFIFINKFKFIQKTDEEKEEEYRLKMGYTKEDWEYHKKKSIERMEKLKQSGKYKKYLRSKNK", "length": 279 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E25-1", "protein_name": "DRBM domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSNKSHTSEKVQLNEFLQKKKQPIPIYHTESKGSEHNKDFKSIVVVNGKQIESDWKKSKKESEKDCAKNILEFIETLDGYPIYFTPFSKDPPQNNKKIYDEKLQAVYNSVSSGIEGLNNNSFFTKIENNNNNSSSNNNNNLDHNHSNDSSHTSTDNNDNNSNNHNNNNNNQINIDLTMENVNISQSKTITNEGTLNNDNDNNNNSIQQQQHQPQPQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQCFDKDKTNLKKKKKIPFSYNTDLIEHIDLFKRQDFPQTYPSRTTYTDTGHTQQLQKQVFLLTEKIGLMELFYKKQIRVILKSHHNLETELSALKSFVEDCSVTPIEGLELYSIPVPLNPNAKPSAGTTPVLSKSETQNEIIQPTKPPTKPPASCLIKKKIPNVNMKATNKTTTTTSTSTSNSSTTIKTTDSFKNTTNNQHPNTLKPMVSKINQQTSDFIFPLPKPIIRRNPIGNGNLEKKIEKKNSKPNTIVLGVDTQSQSKTKITPSPTTPPPETTPTTPTTTATPTTPTTPTTPTTTATPPPTTTATPPPTTTATPPPTATTPPPTTATTTPPPPPIIATTKTTATATATTIPIDLNEIQIPIRSPQDLTVNQSMISTAMMIASAAQRNPKLTMKLKRKLEESPTLMSKLQKIQFEKEEEILCSQDLHSPIMSPQSPTHQPKTLEPLSPTKKSTQKSPPPTSPSPIVTRARASSNLLPIQNLISKK", "length": 733 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E47-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKSGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55E48-1", "protein_name": "thioredoxin-dependent peroxiredoxin", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTKLKVGNIAPDFEAKNYLGQIVTLKEFKEKSQPIVLYFYPKDNSPECQKSCEFRDKYQKSIEAGAEVIGVSSDGEDSHKSFVSKYSLPFTLLTDKHSKLAKLYGVNGILLPGRKTFIIDKHGFMAVFMMVYSVQLLMSMNL", "length": 142 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55ED8-1", "protein_name": "Decapping nuclease", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MKQTLNVIGLINFIKKQRSFNKSPITITKPLEITRFSYEGNQLFPAKLKKFKNPTIDSDLLVGFQGPDSIESDSQTPLSLVLNKLIETKHDVSKSNFISFRNSFRKLFESMYDSEKWNIQVQRINSTIHLGMDNPTQDFHQLKNFHLKSMYSGNYFEKISTIDNNNNPNDNKHKYCSIIQSKLFNNNFILACEIDCWKKSIQNNNNNQNNNNNENNNNDDDDENYNIDDYVELKTSRDIEDSKANYQFRSKKLIRIWFQAYIAGVSKIFLGIRNDDFFLKKCLNFNTHDLPNQAINWNKDEMLIYGNEILEFIKNNTCSGKSYTLSFNYPIISLVESDSINIINDQYLQYYLNIPKNFENNYNQNNNQNNNNNNNNENNSDDTKNNNIQNNNENNNIQNNNENNNQNNNEKNQKRNFGEEKEIKGDENEERLSKKQKKLE", "length": 440 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55EZ2-1", "protein_name": "Reverse transcriptase domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIAKTQIKCTTIYAPAKSNERHEWYKENLTEEILHSDIITGDFNVDCSVDNNLNKYIKTIFDEFEFTEIKNGITFPRNKSTIDRVFVSKKILHLNPIVTTKEIKLKSDHNMVIIELKIPEYEQQKKGERLWRQNLETLKMNSTSLKINKTIKYYNKKFEENTSKWYKLNICEQWLKLKDEIKKLSINIEIRESNKTKNKLKELAEKLETAKDSRAIFLKEEINNILKEQVRIKQANQTNTHINNKETPSKYLTRRLKVQRKTNEIPQILDPSNNCLVTKNEDILEVARRYYENLYQKRECNEDTHHELLKTFNKRIDQKILDEINQPIEEYEIRLGIEKIQEGKAPGKDGLLPTFYKNHINEILPIISKLYNHFWNTTIPKDFKQGILITIYKNKGDPNNLDNYRPITLLNVDYKIYSKIINNRILKFLNKIISPFQTGFVPRRLLHDNIITLNSTIEIIKREINTKEDMEPIITFYDFEKAFDSISHNAILRTLAHLKLPLKMVLTIMNLLNESETSVYINNSLSKSFTSKRGTKQGDPISPTIFALVVECMATTIINDRCINGVTKETIKILQFADDTATIAYNFMDHFLMNEWIKKFCQATSAKINQTKCSCITFKWNTRTLYTVIKSNERYLGFDFNNKGIKSKINTISDNIRAKLVTWNSTSSTYMGRLIMAKTYALSQLTFHTYINTTPQHNSIENNIVKFVFNTKSKNSLSLQRRQNNYINGGLNLWNLKTRELAQKAWLFERYLHQRVSNTPSSYIKLWEEELKNNNNNKTTTKQNQLQLHWQCKQAWTQLKTPQNKQTHYEHLPKLKKIYEDMMTTQSPEHNKFIPTPGQKEIMTKINSKHLPFKEIKKIINMKGRDLLWRYTLKALPKIYNMPCQQCGEDETSEHIFFNCKAHIKNTQEIFNYTLTKCGHTTHTWNVKILNHLQIALVANLIAIIFDKIWHKRNKLIHDEKEIIIHRQQVIRELIKTQRAAWDRTQAVINKTLRIKSKQRPEEQNKLDSLISLKLLQFSRQWNSPLHAIELPKHLKKYNNSLSTFYK", "length": 1047 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55F94-1", "protein_name": "Dynamin-like protein A", "gene_name": "dlpA", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSVFKKKDKSDDKKKKHDEETPQGTFQPASQSTSNTNLNSLASSVNNGASVGSTNGSTPNNSNGSTPTYNHNNSAEELEKQKKEEDEKRKKSELEAAAAVVAKKKEDEEKQRKEQVELERKRRDEEIRRTNAAAANAANKELNEQVEISSLEQMGKLDPSSTIHDMFSFFPNEVYNSYEKLQYFSRDLNTAVSHPEIVFVGPRSSGKSSLIEAFIGRALNIVGGGNIVGVGGSNANGCSKRVLYLQFTNNIDFEVPKVTIKKDNTIKEFDHDIIVSIEQLNENLAKRNQLTNDYIEEPIYVSIESRTTLNLTLIDSPGLLFDQSQAESNKIESIVSSLLRPSHRLIIAVESCSQDWKSMSMGQYLKKIDPELSRSTFVFTKFHHTVRGFSSTRDINKYLSGTVPDIKGFFVTLPNHQVRASYSEANRFQEKIYQAHKRDMHALEQLQYDKRYERTIGVAPLRRYILNIVWKSYQDTIPRILKHLRSKRQTAEATLNELQKQSSSLDSTKLRSIASNYTVTFLQITEKLLSGTSEGNPSANGQTLDEEKSQQGDCGEWVDAYKEAIYIDPEEWNIPYWSSKLYGGQQLERLMAEFKAVCDNSKISEVKMDDIATASGINKLNNIPNYAWAASDLTSLISRDTFVPLIEQLCERAMYIMKRLTDIADKVIDSRRKSRCIGSSPFGGNGLNNINSGGNNGININDRLSNTDMDSLDQYPFFTHHVKNLYYDFVHRAAKGCKEKCMDEFYSSRTIYWELTEHPDSSLPSIRNDHHETKTAVCQLATKLFDSIRQRITKNVLLKLYNFFLVPMQTDLWNEIQAQITCLSNEQLEQLFEVQATREQLKQEEKKQQQILEKYSQIDEQFLKAASLFCRPLSNPTPSA", "length": 880 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55FX4-1", "protein_name": "SET domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDINSNHIKKINDFKDKGNKEFNKEKNKDKLNKRAITYFQLGIKYFNDEKHKIEINDQINKLISILYSNLSLMYLKGDEIILSLEASNKSIEFNNQNSKAFYYQSICKSYLCDYKGSMESIDKAISISKQDEKVVQQRNRLIEITNNKVKEDVYFENVLKNQKLENVAYENSIEKGRYLISKRLIKRGEEILRIAPFSFSLNGKYVSKFCGVCYQKKSIDNLLKCKDCDDFAICKECKAPNEPLSKYHPNDLCVLYKLNNEYYKMNNFEIANEDNKERGLTDERRLYINTIYNIFKNKTNNKAVVEVDNAISSSVIDVLNLSKKLLNHTNESQRAYSDSTKMKTDILELIFKSFYGANTLKKDEISNIIRIVDCNSHGYSDVISQKKKASGLYPFSCYTNHSCIPNSDYFIDKHGVMVLYASSDIQESEAITISYIYFLNRVEKRRKDLLNGHNFFCTCDQCSFQSSLTEEVCDKCNEIIPSTIGNSNLVYKEPKSLKETGFNYICPKGHTKSSLVYDIDNDQLYPTIAENYSKCKDLRNFRKINIFKEMLENRDFVKKLTPREFEVTPLAKYIANPKKSNSMLFEELINLVRGSVECGLTKSIEESNYSTYLVYDYYDLYKSLLLESKPQILKLNSIRDIIIKLLTPMVYNQNKPRIDKKLNKHLSNKINLKKNK", "length": 676 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55G93-1", "protein_name": "Tubulin-specific chaperone D", "gene_name": "tbcd", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MENSEDISLNSSEKSIESSVVNLEDQQQSQQQTQQQTCQKTFVQEAPELTILIDKLIQLKHSNKDELISNTTRIIYIIDQYLEQPTLLDIHLNDIIQPLINFIKSNYINNSNNNNTTTTTTTIMTETEIVIKKLSIKNSFRIIYVLSKVRGFKTIVKLFQHEAIDLLPVLDQLEISYHQWVNINKQRDRLNEISVSYSSGINLKNYIKPEEESEQEVVDENNNNINNNHNIDDEYNENIISWEEVYVLALWVSLLVIIPFKFSSLDSASSGTASAAGDGGDGDGDGQLKSISSRILKLGKLALSDVSKIRDSFSELLSKLLNRPDMKFEQKQFIKWCTNSIQLISNNNNNNNQNNSSNNNILLIIGIYSTLATMFKKGNRLDFLPIDMNLYEKIMEANKYLSLSGSERITKKIFLKLLQRIAIIMLPPVSASWRYQKIIKPLLLKGELIKQINNNNNNNNNENNNEEGEEEEEEIPEEIDEILEEIMKSLKDKDTIIRWTSAKAIGRIVNLLPKDMGDQVIGLVIDQMFEKNEFIDADPSAWHGGCLALAELARRGLLLPERLDVVVPLVIRALFFDIIKGTYSIGSHVRDSACYLCWALARTYHNSILSPYLLPICRNLVVVSLYDREINCRKSASAAFQEMVGRHQGLVPNGIEIVTSADFFTVGNKNNSFTSLTTFIGKFQIDYYPIVIKHLATIKIYNWDLEIRQLASKSIHLLTNINPNDIVSNYLPLIIPNTQSDLVHVKHGASLAISEILISLFENNNINLLSDNLKMMILMTIKNTKNEKLFKGKGGVLIRIGMCKIIYSICLVEFSLDKNLSEIKKPTESTSTNGNEDRAAALKLKIAMLKAKTASQINKPIITPPSSKSTTNNNNNNNNNNLNDNEIAFNIILGYLNENLNHPNEEVQKEASKAFELLFSKYISSNEKISLLLELIDSHCKTLKFDINRSARRGSSLLLGSLPFNSANLSYDLLSKVVNELILSIFQDDPKFKDIETRVNSISSLYKIGIYILNLIFKNQENEQKEEEDFKKSKNYNLFIKIWNCLGLATNDYSIDKRGDIGSWVRELSCKVLFDFIKFIITNQNSSTTTTTASTTDLSIENLINEKMITEFICKLFQLSGEKLDKIRDVACKIIHELLWIENPSSINNIPHKEELKKIIVKDQDVHFNWFRTEESLPLICKVLKFNCYLYPLLFGLFSSLGGTSKYLINDSIQSIKQYFSSFDNDEKERFEKIISFSKAILEITNNTTQRMIQPTFRSIYNLLSTHIFDFLIINNLNEQSIFETILFNCYQIIESNQDDIYLLLNSIELFSYFFIQFENNNNEYIKDYSLKALLLLLSNLKYPKVRKLASDQLKKSTRLFINNNGDDETPSLIKSLIFNTKWDDSVDLIIEPLKSLLLLLNQKHLLELLSENPTKKPIPLAPPITSIEELKDKIQNPHKQSDDNNNNNNGELINNNTENNNNNNFDDNLPEDSQDLMEI", "length": 1480 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GP8-1", "protein_name": "Rho GTPase-activating protein gacO", "gene_name": "gacO", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSKLPPPPVQSSPQGFQLPSLHSVQLKPVRPPPQPTQQQLASNTSPREVGTSLSPQSPSNNINPSSSSSSPSSSIRQSPSSSPNVARKVPPTPTNNNGGPPTTTTTTTTTMPPPPAFIKKLSPSSSPILPKRIVSSPPLNGNTAPPPPPIVHLPPPPPTNLPPPPTLSPSSSTTTSPSSSSLNLSGGVPLPPRILRNSDGSANNNNNSNNNSNNNINSLNLSTSGGIPPPPSFFNNNNNNNNNSGSFVNSASSNGSPSLQSQNSVGYFKPPPPPVPTRSASLDPKQMGQFIKPQQNQNNSNNINNINNNNNNIILPPPPNININNNNFVPYIPSNNNQQQSTTPPPIVSISPLKRNSIDNSVVNKRLSQDLNTMLVNRLQHGLSPPVATPFFDDKILGSASKSAELKEKRDQEERERRERERIKKEKEDSEKKEKKEKKGKEEQEKKDKKKKEEQEKKDKKKKEEEEKKSKSSSSSSSSSKKSSSDNTIVNQNIFNNTLSQIMENQRDAQSLSPSSLPYPLILKLLTESIMSLNGPYTEGIFRITGSGTEVNRLKKQINEHDFSLDTQDPHVLAGLLKLWLRELVHPIIPSELYNDAIKSRSKEEVSRIISLIPDQNKEVLNFLIPFLKNVSQPHYAQYSKMDIDNVAMVFSPGLLRSTVLTTDLLLNSQYEKDFVKCLIEMSP", "length": 684 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q55GR8-1", "protein_name": "Thiamin pyrophosphokinase thiamin-binding domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEKQEEEVQQQQQQQQQQQQPDKNNKETITWDVAEYGGYLFDKKLKAHNPLNHQMPLQYHHSQSTPHIPSSLSTSSTTSIKKPSSSLSDDESGGSSSSTPHSSNTPRKQFSFDDHCALILANQKLPKKLVDYFWDKCSVRICADGGANRLYSLGTKINQSSRWIPDYIKGDLDSLHEGVSDFFSKKGSSIVLDSSQDTSDLQKCFELIIDLEKGSGIKYRKIFILGGLGGSFSHEFANVNTLFDHPGRKIILASKDNLAWLLSSTYNHNIICRSETKCSLIPLSSKASQVTTSGLKWNLVKQSLNFGELISTSNVSLDNKVCVETSNPLIFIVDINP", "length": 337 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q561S0-1", "protein_name": "NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial", "gene_name": "Ndufa10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALRLLRLVPASASARGLAAGAQRVGRIHTSVHCKLRYGLLASILGDKTTKKLHEYSRVITVDGNICSGKNKLARDIAEQLGMKHYPEAGIQYSSSTTGDGRPLDIEFSGSCSLEKFYDNPKSNDGNSYRLQSWLYASRLLQYSDALEHLLSTGQGVVLERSIYSDFVFLEAMYNQGFIRKQCVDHYNEIKRLTLPEYLPPHAVIYIDVPVSEIQSRIQKKGDPHEMKVTSAYLQDIEDAYKKTFLPKMSEICEVLVYSSWEAEDSTKVVEDIEYLNYNKGPWLKQDDRTFHNLRMLVQDKREVLNYTTVPVYLPEITIGAHQGSRIYDSFRELPGRKYAPGYNADVGDKWIWLK", "length": 355 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q568T5-1", "protein_name": "Chondrolectin", "gene_name": "chodl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRATLRILCALTFLVSCSRGARVVSGQTVCQGNPEHPCYKIAYFKDVSSRVAFWEALQACEMDGGSLLSIENTAEQKHIEHLLRELSVSSSTGPASITDGDFWIGLTREEGDNAQEPGAFASCPNLYRWTDGSVSLFRNWYADEPSCGGEACVVMYHQPTALAGPGGPYLYQWNDDRCNMKHNFICKYEPESHLVKVQSDRPGGHDVDLSTEDKEDRRTPPTDEDESPRLIIAGPSSMLLIYVIIPTIPLLLLILVASGTCCFQMLSKSKPRTKTSVNQSTLWISKTPKIDSGMEV", "length": 296 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5HYN5-1", "protein_name": "Cancer/testis antigen family 45 member A1", "gene_name": "CT45A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTDKTEKVAVDPETVFKRPRECDSPSYQKRQRMALLARKQGAGDSLIAGSAMSKAKKLMTGHAIPPSQLDSQIDDFTGFSKDRMMQKPGSNAPVGGNVTSSFSGDDLECRETASSPKSQREINADIKRKLVKELRCVGQKYEKIFEMLEGVQGPTAVRKRFFESIIKEAARCMRRDFVKHLKKKLKRMI", "length": 189 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSKDLAIGVIFILQCSMGILRHFILLSYYLMLHYNKHSLKPIDLILMNMFIANFLIIFPKSMLQTVEAFGIKLLFSVFVCKFLLYIERVGRSVSIATVCLLSVFQAITISPRNSCLYGLKVKVPKYISLSIFLCWALYFVVNMILPVYAYIKWSSNNMTYKRTLKYCFSVGHDEFTGSFFTILFVFPEVFLAILIVWSGSSMVVILYRHKQQVQHIYCNYASTRTSPESRATKSIVVLVSVFICFYSISSILYGCIALFCDNSWSLINIANIISLCFPVLGSFVVSHNPDFPRFSLSWIRNTRRV", "length": 306 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3E9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vom1r15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVNDRMESKDLAVGVIFILQCSMGILRHFTLLSYYLMLHYNKHTLKPIDLILMNMFIANFLLIFSKSVLQTVEIFGMELFFNVFVCKFLLYIERVGRSVSVATVCLLSVFQAITISPRNSCLNGLKVKVPKYINLSIFFCWPLYFVINMILPVYGCIKWNSNNMTYKRSVKYCFSIGHDELTSSIFTILFVFPEVFLAILIVLSGSSMVVTLYRHKQQVQHIYCNYACTRTSPESRATKSIVVLVSVFICFYSVSSILYGCIALFCDDSWWLINIAHIISLCFPIFGSFLVSHNPALSRFSLSWIKNTRRV", "length": 311 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5J3F0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "LOC100911184", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDFWNLAIRIIFLSQIIIGILGNVSLLFYYLVLYYREFTLKSTELILMHLMVANIIIIFSAGVPQTMTIWGMKQFLNDFGCKLLLYIHAVGRSVSICTTCLLSVFQAMTIRPQKFCGNDHKVTMERYLGCFISFLWVLYFLVNFIFLVYTYIKKNSNNETRKRDFGYCSTVGSDKISDSLYATLVMCPEVFFSVLIAWSSGSMIVILYRHKQKVKYIYSTHVSRRDYPESRATQNILAQMFTFLAFYTLSSTLRGSIALLSNHSWWLMNINHFTSLCFPSFGPFVLMSHYSIVSRFILFWLRKNCSNFLL", "length": 310 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JQC4-1", "protein_name": "Cancer/testis antigen 47A", "gene_name": "CT47A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSATGDRHPTQGDQEAPVSQEGAQAEAAGAGNQEGGDSGPDSSDVVPAAEVVGVAGPVEGLGEEEGEQAAGLAAVPRGGSAEEDSDIGPATEEEEEEEGNEAANFDLAVVARRYPASGIHFVLLDMVHSLLHRLSHNDHILIENRQLSRLMVGPHAAARNLWGNLPPLLLPQRLGAGAAARAGEGLGLIQEAASVPEPAVPADLAEMAREPAEEAAEEKLSEEATEEPDAEEPATEEPTAQEATAPEEVTKSQPEKWDEEAQDAAGEEEKEQEKEKDAENKVKNSKGT", "length": 288 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5QNN9-1", "protein_name": "Trace amine associated receptor 12e", "gene_name": "taar12e", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSLNETQTENILLCYPLLSNSCPKLHRLAVVQVGLYVFLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGLLVMPYSMVRSVEGCWYLGDVVCKVHSSLDMTFCISSLLHLGLISVDRYWAICDPLRYRLRVTNITVTVFIVFIWLFSFVYSFYVVFSGVNTVGLETFIMQVYCVGSCVLYFNKQWGLICPILVFFLPGAIMSSLYMKIFHVARKHAKVMSERVTGGLKSQSSAQRERKAAKILAIVMGVFLFCWLPFFTVNALDPFFNFFTPADIFDAVIWFAYLNSTCNPLIYGFFYPCFQKAFKILIFTYICGVRNLDTFA", "length": 337 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5QNP0-1", "protein_name": "Trace amine associated receptor 12g", "gene_name": "taar12g", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSNESENIQLCYPLLSNSCPKLHRLAVVQVGLYICLLLMILTTVFGNLLIIISISHFKHLQSPTHLIVRSLAACDCLLGSLVMPNSMVRSVEGCWYLGDVVCKVHSSLDMTLCISSLLHLGLISVDRYLAICDPLRYRIRVTNTTVTVFTVFIWLFSVVYSFYVKFSGITAVGLEMLILQTYCVGRCVVFFNKQWGLICPVLAFFLPGAIMSSLYMKIFHVARKQAKVISERVTGGLKSQSSAQRERKAAKTLAIVMGVFLFCWMPFFTLTALDPFFNFLSSADVFDALFWFAYLNSACNPLIYGFFYPCFQKAFKILIFTYICGVKKANTLTFE", "length": 336 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5R1F6-1", "protein_name": "T cell receptor alpha variable 5N-4", "gene_name": "Trav5d-4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTYAPTLFMFLWLQLDGMSQGEQVEQLPSILRVQEGSSASINCTYENSASNYFPWYKQEPGENPKLIIDIRSNMERKQTQGLIVLLDKKAKRFSLHITDTQPGDSAMYFCAAS", "length": 114 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKI7-1", "protein_name": "Solute carrier family 7 member 13", "gene_name": "Slc7a13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMDIEKKIYLKRQLGYFWGTNFLIINIIGAGIFVSPKGVLQYSSMNVGVSLCVWVFCAVLSMTSTLCAAEIGITFPYTVAHYYFLKRCFGPFVAFLRLWTSLFTGPGVLASQALLLAEYGIQPFYPSCSAPAVPKKCLALAMLWIVGILNSRGVKELSWLQTVSMVLKMGILSFISLSGLFLLVTGRKENVRRLQNAFDAEFPEVSRLIEAIFQGYFAFSGGGSFTYVAGELKEPSKTIPRCIFTALPLVTVVYLLANLSYLTVLSPQELLSSDAVALTWTDRVIPQLTWSVPFAISASLFSNLVTSVFETSRTSYIASRNGQLPLLCSTLNVHSSPFIAVLLDVSMGSIAIVLTNLIELINYLFFVFSIWTVLSVIGILKLRYQEPNLHRPYKVFSPFLFITAAISLSMVLIPLIKSPKMQYIYVFLFFLGGLLFYVPLIHFKLKLIWFQKLTCYLQLLFNICIPDVSDEHVAEEES", "length": 479 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63550-1", "protein_name": "BPI fold containing family A, member 2F", "gene_name": "Bpifa2f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFQLGSLVVLCGLLIGTSGSLFDIFQNPELDVESVWSEINYRIRYALETMDLDMLADYLSKRGIELKIKDLRILNLNHEVSPNGDEVTLKMPMALNASLSLPARDLTTDVSISMEAITSFAIEKDPKTGRRVLNMQRCSLNTDNTSISLLNRKSNFVNLALDSALYLIKRGLTLPVRRQLCPVLQLIISNTFHPDEISNPQTAIST", "length": 206 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q675C0-1", "protein_name": "Taste receptor type 2 member 102", "gene_name": "Tas2r102", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPVIYSFATLLIHVEFIFGNLSNGFIVLSNFWDWVIKRKLSTIDKILLTLAISRITLIWEIYTWFTSVYGPSSFAIGMKLQILYFTWILSSHFSLWFATALSIFYLLRIANCSWKIFLYLKWRLKQVIVGMLLASLVFLPGILTQRTLEERPYRYGGNTSEDSMETDFARFTELILFNLTIFSVIPFSLASISFLLLIFSLWKHLRKMQLSSRGHGDPSTKAHTNALRIMVSFLLLYSIYFLSLLLSWIAQKHHSKLVDIIGIITGLMYPSAHSFILILGNSKLMQTSLWILSHLRCRLKGENILNPSGNQVTSCYIFCIANKSVS", "length": 327 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FP3-1", "protein_name": "C-C motif chemokine 6", "gene_name": "Ccl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRHSKTAISFFILVAVLGSQAGLIQDTVKEDRPFNPTIIHQGFQDSSDCCFSYASQIPCSRFIYYFPTSGGCTKPGIIFVTRKRKRVCANPSDQRVQTCISTLKLGPRSGNSAIA", "length": 115 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EKJ0-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 2B", "gene_name": "GTF2IRD2B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRKIDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTERMRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVEKSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT", "length": 949 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NXT2-1", "protein_name": "Histone H3.3C", "gene_name": "H3-5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSTPSTCGVKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFNTDLRFQSAAVGALQEASEAYLVGLLEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 135 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P3W6-1", "protein_name": "NBPF family member NBPF10", "gene_name": "NBPF10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRSLKEKCFLTQLAGFLANRQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKYEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRHRWDQVKKEDQEATGPRLSRELLDEKGPEVLQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAFDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLEEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDEEEEEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYVLEQQHVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYVDNRFFTLTVTSLHLVFQMGVIFPQ", "length": 3795 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UGQ3-1", "protein_name": "Secretoglobin family 2B member 2", "gene_name": "Scgb2b2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLALLVTGELGFQRTEACIPFFGVYLGILSGNRIGLHTELAPFDPTVEEKEAFEKIQDCYEEEGLKAKTEDMKLMTTILFSSECRSYYTKEVLKNILVKFSKKLTHGS", "length": 114 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6YCH2-1", "protein_name": "TD and POZ domain-containing protein 4", "gene_name": "Tdpoz4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGELEAKSRGDTQSHEQKLCYRWTISNFSFFVEETEEYITSLVFSLEDNDKMTWCLRVYPTGVDEKNKDYVSLYLILLSCEKGSVWAKFEVCILNAKGEKCNTERIPSFSRIQPHQPFGFEKFITRDSFLSPAQVLTPDDKFTLLCKVSVLQDSFSISGQNPRPAIKVTRCTLENDVGELWENPLFTDCSLLVAGHEFRAHKAILAARSPVFRAMFEHEMEERLTNCVEIHDLDPQVFKEMMGFIYTGKVPHLHSHSMACDLLAAADRYGLEDLMVMCEDALCRSLSVENAAHTLIVADLHSTEHLKTQALDFIIVYASEVSKTSGWMSMVESHPRLVAEAFHSLASAQRVFWALPFKQLKWSLRPTQL", "length": 370 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZMA2-1", "protein_name": "Olfactory receptor", "gene_name": "Or1o1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCTQSPGFILLGLSSDPEKWQLFFSIFLALYLLGFLGNLLLLLAIGADVHLHTPMYFFLSQLSLVDLCFITTTAPKMLEALWTGDGSISFSGCLTQMCLFGVFADMDNLLLAVMAIDRYAAICQPLLYPLLMTPCRCGVLACGSWGIAHCASLVYTLLLSQLSFHSNQEIPHFFCDSRPLLWLSCSDTHLNEFLMMVLSALLGISALLCIVSSYGCIFCAVARVPSAKGRRKALATCSSHLSVVLLFYSTVFATYLKPPSTSHSSGEVVAAVMYTLITPTLNPFIYSLRNKDVKNSLKKLLNMEKPLD", "length": 309 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q70YC5-1", "protein_name": "Protein ZNF365", "gene_name": "ZNF365", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQKAFEESRYPWQESFENVAVCLPLRCPRCGDHTRFRSLSSLRAHLEFSHSYEERTLLTKCSLFPSLKDTDLVTSSELLKPGKLQSSGNVVKQKPSYVNLYSISHEHSKDRKPFEVVAERPVSYVQTYTAMDLHADSLDGTRSGPGLPTSDTKASFEAHVREKFNRMVEAVDRTIEKRIDKLTKELAQKTAELLEVRAAFVQLTQKKQEVQRRERALNRQVDVAVEMIAVLRQRLTESEEELLRKEEEVVTFNHFLEAAAEKEVQGKARLQDFIENLLQRVELAEKQLEYYQSQQASGFVRDLSGHVLTDISSNRKPKCLSRGHPHSVCNHPDLKAHFHPKGRNHLKKAKDDRASMQPAKAIHEQAESSRDLCRPPKKGELLGFGRKGNIRPKMAKKKPTAIVNII", "length": 407 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71LE2-1", "protein_name": "Histone H3.3", "gene_name": "H3-3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRPGTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA", "length": 136 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7KR10-1", "protein_name": "Probable cytochrome P450 12d1 distal, mitochondrial", "gene_name": "Cyp12d1-d", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNTLSSARSVAIYVGPVRSSRSASVLAHEQAKSSITEEHKTYDEIPRPNKFKFMRAFMPGGEFQNASITEYTSAMRKRYGDIYVMPGMFGRKDWVTTFNTKDIEMVFRNEGIWPRRDGLDSIVYFREHVRPDVYGEVQGLVASQNEAWGKLRSAINPIFMQPRGLRMYYEPLSNINNEFIERIKEIRDPKTLEVPEDFTDEISRLVFESLGLVAFDRQMGLIRKNRDNSDALTLFQTSRDIFRLTFKLDIQPSMWKIISTPTYRKMKRTLNDSLNVSQKMLKENQDALEKRRQAGEKINSNSMLERLMEIDPKVAVIMSLDILFAGVDATATLLSAVLLCLSKHPDKQAKLREELLSIMPTKDSLLNEENMKDMPYLRAVIKETLRYYPNGFGTMRTCQNDVILSGYRVPKGTTVLLGSNVLMKEATYYPRPDEFLPERWLRDPETGKKMQVSPFTFLPFGFGPRMCIGKRVVDLEMETTVAKLIRNFHVEFNRDASRPFKTMFLMEPAITFPFKFTDIEQ", "length": 521 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7M715-1", "protein_name": "Taste receptor type 2 member 117", "gene_name": "Tas2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFWKILSVISQSTLSVILIVELVIGIIGNGFMVLVHCMDWVKKKKMSLVNQILTALSISRIFQLCLLFISLVINFSYTDLTTSSRMIQVMYNAWILANHFSIWIATCLTVLYFLKIANFSNSFFLYLKWRVEKVVSVTLLVSLLLLILNILLTNLETDMWTNEYQRNISCSFSSHYYAKCHRQVLRLHIIFLSVPVVLSLSTFLLLIFSLWTHHKRMQQHVQGGRDARTTAHFKALQTVIAFFLLYSIFILSVLIQIWKYELLKKNLFVVFCEVVYIAFPTFHSYILIVGDMKLRQACLPLCIIAAEIQTTLCRNFRSLKYFRLCCIF", "length": 330 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7M719-1", "protein_name": "Taste receptor type 2", "gene_name": "Tas2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAVLRSILTIIFILEFFIGNLGNGFIALVQCMDLRKRRTFPSADHFLTALAISRLALIWVLFLDSFLFIQSPLLMTRNTLRLIQTAWNISNHFSIWFATSLSIFYLFKIAIFSNYLFFYLKRRVKRVVLVILLLSMILLFFNIFLEIKHIDVWIYGTKRNITNGLSSNSFSEFSRLILIPSLMFTLVPFGVSLIAFLLLIFSLMKHVRKMQYYTKGCKDVRTMAHTTALQTVVAFLLLYTTFFLSLVVEVSTLEMDESLMLLFAKVTIMIFPSIHSCIFILKHNKLRQDLLSVLKWLQYWCKREKTLDS", "length": 310 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTZ2-1", "protein_name": "Ubiquitin carboxyl-terminal hydrolase 17-like protein 1", "gene_name": "USP17L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDDSLYLGGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSSETRVDLCDDLAPVARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYENASLQCLTYTLPLANYMLSREHSQTCQRPKCCMLCTMQAHITWALHSPGHVIQPSQALAAGFHRGKQEDVHEFLMFTVDAMKKACLPGHKQVDHHCKDTTLIHQIFGGCWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVKQALEQLVKPEELNGENAYHCGLCLQRAPASNTLTLHTSAKVLILVLKRFSDVAGNKLAKNVQYPECLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHDGHYFSYVKAQEVQWYKMDDAEVTVCSIISVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRAKQGELKRDHPCLQAPELDEHLVERATQESTLDHWKFLQEQNKTKPEFNVGKVEGTLPPNALVIHQSKYKCGMKNHHPEQQSSLLNLSSTTRTDQESMNTGTLASLQGRTRRAKGKNKHSKRALLVCQ", "length": 530 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TMR7-1", "protein_name": "Monocarboxylate transporter 7", "gene_name": "Slc16a6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQKNSKLCSRANVYTQVPDGGWGWVVAASFFFIEVFTYGVIKSFGVFFNDLMDSFDESNSKISWIISICVFIMTFTAPLSTILTNRFGHRLVVMGGGLLISVGMIAASFSQRVYQMYISIGIVSGLGYCFSFLPTVTILSQYFDKRRSMVTAVASTGECFAMFAFAPAITALKEHIGWRYSLLFVGLLQLNVMVCGALLRPIIIKGPGSPKAIPLEPRREVQYMLENEKTRTSIDSIDSGVELTTSPKNVPSEAKREQEVRVEQQQTLVVGPKHSQKRAPLLDFSILKDRSFICYTLFGLFATLGFFAPSLYIIPLGISLGIHPDRAAFLLSTMAIAEVFGRIGMGLVLNREPIRKIYIELICVILLTVSLFAFTFATEFWGLMLCSVFFGSMVGTIGGTHIPLLAEDDVVGIEKMSSAAGVYVFIQSISGLAGPPLAGLLVDQSKIYSRAFYSCAAGMALAAVCLALVRPCKKGLCQNPHSGENQTDGHRGKALQDIPEDFLEMDLGKCEPRAHMKMDPV", "length": 522 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TN50-1", "protein_name": "Mas-related G protein-coupled receptor member B8", "gene_name": "Mrgprb8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSSIPDPEADLIQLNGSYHTETSPCVIESRVMILLSIIIAFFGLAGNAMVLWLLAFRMRRNVFSVYILNLAGANFLFLCTHTAFSLEKIIVLFHSVHIHIPLLFYTLSTLAYLAGVSMVTAISAEYWLSGIWPYWYQGQRLKHTTTVICTGLWGLALLLSLLEGKSCGFLGSTYNQDVCWKLDFIIVAWLLVLFAVLSRSIQVLLVRIFCGSQRTPVTKLHVTIVLTALVLVICGFPFGIIFYLLYWTTEVYYIMPCNSFHETILLLSYINSCANPIICLLVGSIRHCRFQCGTLRLLLHRAMQDIPEEEGEELEEVVGERVQNSIP", "length": 328 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TPX8-1", "protein_name": "Oogenesin-2", "gene_name": "Oog2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNFYSPPTLMELARQCLLRDEYLAISALKDLPNMMFPVMFKEAFIDGHTKILTAMIPVWPFPYLSVGTMLKNLNLDTLKAVLEEIDILISKPVFSSRCKLREITLSHDLVVVWAGSHEVEGLPEFMEQEKPVENSPGYGTKNKLKVTTELQFMEGHLDECSTYLLQWAYQREDSIHLHCRKLKIYGLTKAAVIEMFKIVHAEYIEDLELSCLCLEYLDFLNPYLKQMSNLLSLTLDEIIYTLNIDDYRNLNEEKVITVISHLPTFHHLQELYVHGVIFIECLRCLKKPLEVLSFTDCDLSQSDLDYLPYCLNIFELRSLHLTDVRLSNLLLEPLGFLLERVRHTLKSLQLMSCEMGETHFNALLPALSQCYQLTVVNFYGNELSLLFLKKLLHHTAKLSQLADELYPAPQECYDNRDVVLSHRLENFCSELLDILRAIREPKKVTFGTIKCSKCGGSYVYDLETQCCFFEKNPPWA", "length": 476 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TQY5-1", "protein_name": "Olfactory receptor", "gene_name": "Or4k38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSNRTVSSEFIFQGLCSSRQLEIFLLLPFSILYLMAVVGNLFVVILIIIDHHLHSPMYFLLANLSFIDFCLSSVTTPKLTIDLLKENKTISFVGYMRQIVCVHFFAGGEMVLLVTMAYDRYVAICRPLHYSSIMDRQKCIWLVVISWIVGFVHAISQMLLILDLPFCGPRVIDSFFCDIPLVMKLACMNTDTLEILINADSGILATTCFILLLISYTYILLTVQHRSKDGSSKALSTCTSHIIVVLLFFGPIIFIYLWPVSITWVDKFLAVFYSVITPLLNPAIYTLRNKDIKNAIKKLISHK", "length": 305 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TR72-1", "protein_name": "Olfactory receptor", "gene_name": "Or8k25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKYNLTIVTEFILVGITNHHEFQVPLFGLYLIIYLTSLVDNLGMIILTIVDSRLQTPMYFFLRHLATTDLGYSTAVGPKMLRNFLVDQNIISFYACAIQSSFFGMFIVCEFFILSAMSYDRYVAICKPLLYTVIMSQKACWILVTIPYLYSIIVSLLVNIKIFTLSFCGYNVISHFYCDALPLLTLACSNTHEIEAIILIFSAFNLLSSLLIVIGSYLLILMAILRINSAEGKWKAFSTCGSHLTVVIVFYGTLIFMYLQPTFTHSIDTGKVISIFYTQVIPMLNPLTYSLRNKDVKDVLKKPMEKVHNLFS", "length": 313 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7TSF0-1", "protein_name": "Desmoglein-1-gamma", "gene_name": "Dsg1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDWHSFRIAALLLTSLVVLEVNSEFQIQVRDHNAKNGTIKWHSIRRQKREWIKFAAACREGEDNSKRNPIAKIHSDCAANQPVTYRISGVGIDQPPYGIFIINQKTGEINITSIVDREVTPFFIIYCRALNAQGQDLENPLELRVRVMDINDNPPVFSMTTFLGQIEENSNANTLVMKLNATDADEPNNLNSMIAFKIIRQEPSDSPMFTINRKTGEIRTMNNFLDREQYSQYSLVVRGSDRDGGADGMSAESECSITILDVNDNIPYLEQSSYDITIEENTLHSQLLQIRVIDLDEEFSDNWKAIIFFISGNEGNWFEIEMNERTNVGTLKVVKPLDYEAVKNLQLCIGVRNVAEFHQSIISQYRLTVTLITVTVLNVVKGCVFQPGSKTFIVDSRMEANHTVGEFLATDCETGQATNKFKNVRYRYVMGNNPENLLVVDSGIITLRNRVTMEQYERLNKRYEGTVLSIHDSLQRTCTGTIIMVLCGFWTTTEHPTTSTEKPVTLSITPNVDNVHFGPAGIGLLIMGFLVLGLVPFLLISCDCGGAPGGGAGFEPVPECSDGAIHTWAVEGPQPGGITTICVPQMPPGNANVIEYIDNSGVYTNEYCGREMQDLGGGERTTGFELMDGVKTSAAPEICQEYSGTLRRNSMRECRDGGLNMNFMESYFCQKAYAYADEDEGRPSNDCLLIYDIEGVGSPAGSVGCCSFIEDLDESFLDTLGPKFKKLADISLGKEIDSYPDPDPSWPPQSTEPICPQHMEQLASGHPSISPHFGKTTVISENAYPSGPGVQHPMLIPDPLGYGNITVRESYTTSGTLKPSVHFHDNQQASNVVVTERVVGPISGADLHGMLEIPALRDGTNVIVTERVIAPGSSLPNSLTIPNPRETSNVVVTERVIQPTSGMIGNLSIPP", "length": 911 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q803M0-1", "protein_name": "Protein phosphatase 1 regulatory subunit 3B", "gene_name": "ppp1r3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPIELAMSLYLSSDEFLNPRASKYSRPLQPCLNQCKSSKLSFSSLKEQSEFNGVSRALMIPGRAKKHVSFADHKGLALTVVKIFSEFDDPIDIPDNIDNFFTSSLTVSEGKDKLTLDFDQPSADYLKFRQRIENDHVCLEHCMLKEKSIMGTVKVKNISFEKSVKLRITFNTWKNHTDVECQYVKDTYTGSNRDTFSFEASLPEQVPSHERIEFAICYEVNGDTLWDNNQGKNYRIIQSALRKSSNESNGGHQQYSQSDWDIHFDRYGSPRCSRGIFPHWPSYVGYEDIGPYY", "length": 293 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q80SW5-1", "protein_name": "Embryonic testis differentiation protein", "gene_name": "Etd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDEKNPEAVPRPPEQNTELVPPKKSKSKKPANILIYLIDRHLGRPRNDMDLFEWVWTLK", "length": 59 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VJ6-1", "protein_name": "Zinc finger and SCAN domain containing protein 4C", "gene_name": "Zscan4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASQQAPAKDLQTNNLEFTPTDSSGVQWAEDISNSPSAQLNFSPSNNGCWATQELQSLWKMFNSWLQPEKQTKEQMISQLVLEQFLLTGHCKDKYALTEKWKASGSDMRRFMESLTDECLKPPVMVHVSMQGQEALFSENMPLKEVIKLLKQQQSATRPTPDNEQMPVDTTQDRLLATGQENSENECNNSCNATEANVGESCSGNEMDSLLIIQKEQHPEHEEGNVVCQFPHGARRASQGTPSHHVDFPSAPTTADVPMEEQPKDLSRENISEDKNNCYNTSRNAATQVYSGDNIPRNKSDSLFINKRIYHPEPEVGDIPYGVPQDSTRASQGTSTCLQESLGECFSENDPREVPGLQSRQEQPISDPVLLGKNHEANLPCESHQKRFCRDAKLYKCEECSRMFKHARSLSSHQRTHLNKKSELLCVTCQKMFKRVSDRRTHEIIHMPEKPFKCSTCEKSFSHKTNLKSHEMIHTGEMPYVCSLCSRRFRQSSTYHRHLRNYHRSD", "length": 506 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80VT8-1", "protein_name": "S100 calcium-binding protein, ventral prostate", "gene_name": "S100vp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQNLTSTEQEIMELLMILQEFSVKKIDKLDVQEVKRLFREELPNFLKAMDEATKNKILNDKGKEMPFDEIWDMIGRMALEYRKKNSNALKD", "length": 92 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q810J1-1", "protein_name": "Pregnancy-specific glycoprotein 22", "gene_name": "Psg22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVSSELLSNGWTSWQRVLLTASLLTCWLLPITAGVTIESVPPKLVEGENVLLRVDNLPENLRVFVWYRGVTDMSLGIALYSLDYSTSVTGPKHSGRETLYRNGSLWIQNVTREDTGYYTLQTISKNGKVVSNTSIFLQVNSSLFICGRPSPPALLTIESVPASVAEGGSVLLLVHSLPDNLQSLLWYKGLTVFNKVEIARHRTVKNSSEMGPAYSGREIVYSNGSLLLQNVTWEDTGFYTLQIVNRYWKMELAHIYLQVDTSLSSCCDDFNSVQLRINPVPPHAAEGERVLLQVHNLPEDVQTFLWYKGVYSTQSFKITEYSIVTESLINGYAHSGREILFINGSLLLQDVTEKDSGFYTLVTIDSNVKVETAHVQVNVNKLVTQPVMRVTDSTVRIQGSVVFTCFSDNTGVSIRWLFNNQNLQLTERMTLSPSKCQLRIHTVRKEDAGEYQCEAFNPVSSKTSLPVRLTVMNE", "length": 475 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q863C3-1", "protein_name": "Gastrin-releasing peptide", "gene_name": "GRP", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRGREVPLVLLALVLCLAPRGWAAPVTAGRGGALAKMYTRGNHWAVGHLMGKKSVAESPQLHEEESLKEQLREYAQWEEATRNLLSLLQAKGARGHQMPPWEPLSIHQPAWDSEDVSNFKDTGPQHEGRNPQLN", "length": 134 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q869X2-1", "protein_name": "Probable polyketide synthase 17", "gene_name": "pks17", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MTFNNIKDENNDDIAIIGMGFRFPGGGNNPYQFWNQLSNKMDGISKIPTEKWSRSFYEQKYINNEYGGVLKDEEWKNFDPLFFGISPKEAPIIDPQQRLLMTTLWEAFEDANIKPSTFRGSDTAVFIGMMNTDYQRCQFRDISYVNPYITPGTAGSFISNRLSFSFDLRGPSMTLDTACSSSLNAVYLGCQAIANGDSKMAIVGGVNGIFDPCFSMTFSGLNMLGHKGQCRSFDAGADGYIRSEGGGVCILKKYSDAIKDGDRIYCVIKGGSSNVDGYNAKTNIIQPSMKAQGENIEIALKKSGVNPSDIYYIEAHGTGTPVGDPIEIEAISRIFKDNHTPDAPLYIGSVKSNIGHLESAAGIASLIKVALSLKNRSLVPNIHFEKPNPLIKFEDWNIRVVTDEIQFPINKLINMGINCFGLSGSNCHMILSEAPINYDELLKTTNNNSTSSSSNDDKKEYLIPFSANCNISLDKYIEKLISNQSIYKDTILFKDFVKHQTISKSNLIKRKVITASDWDDFLNKRNETTSTSSLTSTISAPASSTPVIYVFTGQGPQWRDMGKALYETESVFKDAIDHCDKLLANYFGYSILQKLLSLESEDSPEIHHPILAQPSIFLIQVGLVALYKSFGISPSIVVGHSFGEIPSALFSDVISLETAVKIVYYRGLAQNLTMGTGRLLSIGIGADAYLEKCALLYPEIEIACYNDPNSIVITGSEQDLLGAKSTLSAEGVFCAFLGTPCSFHSSKQEMIKEKIFKDLSDLPESNVPCVPFFSTITGSQLSHKGFYNVQYIYDNLRMPVEFTKAISNIFNFIEENESYKNAIFLEIGPHPTLGFYIPKCKPSNSTITSKPIIVSPLHKKKEELTQFKLAISTLYCNGVEIDFASGQQLLPTSSSSGGGDISSFKESTNKLPRYQWDFEEYWDEPNQSKMVKRGPSNNLLGHDQFAGNTLMELFIDIDKSAHQYLKGHKIKGKYLFPGSGYIDNILRQFNGQDITIFNLEFSNPFFLKDGVQHHLQTSITPTTKGEFKVEFFIKDNRNSTKWTKTSNGRIGLFKHNPKNNKLDIEKLKSQCSFTTLTKSEVYNKLLLLSLPYGPTFQRVESCSIGDGCSFFKLSMSPCSEFDKDFLNPSIIDCAFHGLLVLSEGPQEIVFDRLQDMKFYSSNVPSTRPQFIYAFAKFDKIEGNSTHGSLNIILEDGTLLISIKNVKCTSLIRLKKQSIKYPSQNVYSHHWQSKDSPLTLIENQLIEEKSSESKINFEKLLNDKLFNYYLIRLLNQSIKSEFIEFDYKTSTVDTLDIGSKNAKLLEKIQSILNPIDSLDQSIDITSLKQAIIVKSSFKNEIKLVEKSIKRIVSLLKGGESEHFSPSNPSSPNDTPRNNSNNCSSKNNAASSDDADDDTNNEETINQLNNEPFNFSNSQFISNQNQLISKTIVNSFDRLINSIEIGEKKLIKIIDLSSIYQNYQLSKLLLLQLNQLLINLSNNNNIEIEYTIPSNTKNIDSITEETKSISNVLNIKYRSFDLQDDLESNGYLNSNYDLIITSLLLVSTNSIDSNEVLSKLYKLLLPKGQLILMEPPKGVLSFNLLFANDFKQSLEIKSEQEIKSLIIYCGFTKIETNLNTKDDEEQQQPPPPSILIVQAEKRDIESMSLTFSSDPKSLNSSYSNCIFIVSKEQKENPTSYIQEYFDITEFFCQNATIIEADDSELLTKTIESGVGKNDIIFFLVSLEELTIENYKQVTMQYTLVNQILLRNNLSTRFALLTYDSQNGGKNYLGSSLIGTFRYFLEFRSLNIFSIDVDKDSIDNLTLFLRLVDLSTIGDRETIVRNNKIFVQKIFKEPKLLSPSNNYEKNTNNLFLYSNSNLDFSFQSKEKLLHGCVEIKVMSTGINYKDSLFYRGLLPQEVFSKGDIYSPPFGLECAGYITRVAPSGVTRFKVGDQVVGFASHSLSSHVTTHQNKIVLKPENISFNEAAAVCVVYATSYYSIFHIGAFIADKESILVHSATGGVGLASLNLLKWKRNQLKKHGNSEISNDASIYATVGSKEKIDYLQEKYGDLITAIYNSRDTEYCDEIKQQSAQGGVDLILNTLSGDYLSSNFRSLSQVGRIMDLSVTQLVENDSLDFSNFKYHVGYNTIDLDRATKYNSKIIRDILTEVFDAISDGSLENIPVKVFPAIQVKTAIEYINERVHIGKIVVDFENFEQDILKPALQEKENPIQLNKVKKLEHTCDTLNNTILITGQTGIAVHILKWIISGSVLNSNKSQQQVTDFIILSRSSLKWELENLINQTKHKYGDRFRFHYKSVNIADLNSTRTAIDQVYSSCKNVSPIKSVLHFATVYEYILPENITQTVIDNTHNPKAVGAINLHNLSIEKDWKLENFILFSSIGAIIGGSKQCAYSSANLVLDSLSNYRKSIGLASTSINWGGLDAGGVAATDKSVASFLEGQGILLVSLSKILGCLDSVFQPSNSHLSNFMLSSFNIDNLLSSAPQMKRKMDHHLTNYKTSSASSDDSLGDSGSTQAKVISTISELLSIHPSKLNLDTRLKDYGIDSLLTVQLKNWIDKEFTKNLFTHLQLSSSSINSIIQRISSKSTSTSTPNPTNTSKQTATKKT", "length": 2604 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q869Z5-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSHLTPKPNVLNVYGAGTPNFVKVQILLEEKNIPHVYHKIDFSKNEQFDPEFLKFSPNNKIPAIVDNTVEPNGISVFESAAILMYLSEKHQFTDLYADFKTDPALHAKHLEFLFFQMSGVGPMTGQLGWFLRQPEPKNTQAIERYSEEVKRLYRVLDKILSTNTWVAGEQYSIADISLLGWALYFLKGYYDDHITREQFPNVYRWLDLAAKRPAIIKVLETIQPKQK", "length": 227 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AE3-1", "protein_name": "Probable polyketide synthase 9/36", "gene_name": "pks9", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MGNLKNINLKEKGVAIVGIGFRIPSGNNENSISSPDDLFNNLKNGFDGVSSTSERWSDNFHKLGEISSPNAGLLPFKEWKSFDPLFFGINPSEAPLIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHTNKHQDSVLKNAIAQSTSAISNRISYCFDFNGPSLSIDTACSSSLNAVSQGYHSILNGTSNMSIVGGVNLILDVDIIKAYSILSMLSKTHGKCKTFDESGDGFTRGECVGVVVLKNLQDAVKDGNRIYCVINGSSSNVDGNGNMDKVNFYSPSKQSQFNNINSAFKSTNDKLSINDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVASLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNKRNNEKPVSMMINNFGVTGSNCCLLISEFKNNNNFKENINLESQSVNDRVLIPFSANSSNSLNQYQSKFKNIINNQFNFIDFTANQIYSKSNFLYQRSVVIASNSNELFENISNKKQIQTKNSIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGFSVWEKVKTIKDDDLTSIHDPIFAQPALCMISVSLFELYYHWGVNPSFILGHSLGEISASYCSGMIDLDTFCYTVYQRSIAQSKTNGCGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTTMLGSLSSFHTSSQQCTKDSILQLNIESNQPKVPIFSTVTTNLFNESNRFNSQYVYDNIIKPVKFTQTISNIYKHIESNQLNNEIVFIEIAPHPTLLFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQSINLPLYQWDEELYFTQAQTLEQHRKEGPPIDHLGTSNSYNSPFNNSYRTSIDIKNKPFLYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQYLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHGNDIPPKYNIKEIIENKCNLSKLTKNELYTHIKSKTGLNYTGVFQGVTECYIGGDCTLSVVSLESQTNSFLNIPILDTCLHGMIGLSNDQCQIVFDKAIGFKYYSSNIPANLKDYKDSVYVYSHLKSKSVDSFFGSIIVMLSDGSVLYEIEEVVCKSLIPIKDSLKIEYPNDELYKVHLQSKDSPIPTPSSFKSIIYENDFFHSALNIPEDLFKYISTLFYKDIIKRCPEININKINSHSVNEIISSFSKISKHERLFRFVFETIKENGILNSLEENDDAYFEFNEVIIKSSRIISKLLFPLESDNDNEDLPQSLFQNGLMDKIYKCRYLRKKNQMISHVIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIIALLQENPNYQVEIEYTWSDISPAFIADAKNKINKIINDAAITNGFNVIYRPLKIDESLIETQSINPSYYDFVIMSNVLHVVKNIKQAVEQMYQLLTPNGQLLFLEPPYKSVLNDSIVGSFEQWWSFTDTDIRKDRCSMSQQSWCQLLKTCNFKDIAMSKECIFVGIVIHAQKPPISLLNSQPKRDNIIIYGGGNPIFVENIKLYSNSKSLIQIETIQEFNQLLSQSTITNDSIIYFIKTLETLSLDNFKQITLEYIEINRKLLQINSLCKHVLIVSDSRKTNYLASSVVGAARYFDEFQQLKLNTLDFDYDSTQNYINSNNKDMVQFINILTDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFENQNNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINYKDYLNFSGSNSNGDDNTGLPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSHIVTNYKKIQIKPSNLSHNEASSIPIDYLTSFMSLFNIGSLNIEDNESILIHLGSDGFGLSTFEILKWKGFNSNLFVTVNSYETKRYLQDNYGDFITGIYSNTDKSYVTEINKKLIKLGSKKKGVDLILNTLPSDFMDSNFKLLAKYGRIIDLTSNHLNQSEFLKNINFKYNHGYHNFELSLIQKNKIHKCLYEISNAFENGELKTIPIKEFTNLNIKDAIKYITNNKIEKITVSHDHEIYSDIIYRSLDEKEFSILKSNYQINSNNLGKNILVTGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINETKLSNNNIKFHFKSVDIGDSEQVDNAINEILNENQQITNIDSIYHFAFQQITCKVQEINMKHLDISHGAKSMGAINLHNQSIKRNWKLINFVMASSAISLIGSTDLCTYVCANALLDSFSKYRESLGLPSTCICLGAIESTGFVSKNESVSVFLDGGGFHPTPINQVLGLLDLQIQNAGKFTNSMLSNFKPSKFKNNQQTSLFLKFDYLMNLKNNSEETKIENTGNKNIDELFIEKVSELFSMDESKINKNLRLIDYGADSLIIVQLKNWIDKEIGINLITIQQLQNNTISTSMKMILNSLMKNNQNIDDNNKDLPSNRIDYWKNEMKFEESIKPISNEIQSRNNSEKIILLTGTTGFLGGFLLFNMVRLDSCKLIYCLIRNKSKSNNPLDEIINNLKYHQLYEKLNQSQISKIIPIIGDLSMNKLGLSNDDYETISKNVNLIINPGADINQKSSYQDCKLVNVNGVKEIIKLSLSSLKQRIPIVNFSSFSVFFNQSLDKNFDESVLPSIDNIDNLPTEYMKSKVVGEYILLEASKKYNIPSILIRPPSIFLNPETGIGHISDFSLLSIQSCYELGYYPNQFENDFILINTITWLSNNITNIIMNDNCWTDSKMNIYNVHGKQIQSSLIIKPLEKHFNCKHINTNDWIDMVNNSNKKSCIKLKSFHSLDIILKSENNRYKPNENQSISLSTKSLLESMGSYNTDLEITDKMIISHINQIFNLNETI", "length": 2931 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86AF8-1", "protein_name": "Uncharacterized protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFSKFSIKENKPKKVKSNSSKGFNNNEINSTNNNNNNNNNNNNNNNDSDNFINNNDSNNNNNFNNNNNNNSNNINNKTEDSNDISLLINQFIGSSPAPSTCSGSDKFSIKPKKIVTPSKRKNSTSGSDIIDFNNCNNNNNSKSNSDSNNNKYNNSNSNNNSCNNTNNGNERKMKGYDYGNNNSNNNYSSSSRDYNSNNNSSPRDYNNNNNNNNNNNNNNNNNSNNNSPRDYNNSRDYNNNNTNNNSSPRDSNSNNNRNSSSRDFSNNNSSPRDYNNSRNSNNSFLNNNNNNNNNSNNSNDNSPRDYNYSSSNSSPRDYNNNNDTFSKKRNNVGNSILEIKSNPTSPRIKPIMVWPRSSPRIVNKLPPVQSLVDLTEIEMIDDNNNNNNNNNNNNNNNNNNNNNNNSNNNNNKSGSNNNFSDSDSDKDNYNNNNNTNNNSFNSDSDNYNNSNNNNSNSNSNSNSNSNSNSNNNNNNNNNSNNNNNNNNNNNSNNSNKSNNNFSNIKILEKRRKSINEISDNLTTRNIEEIDSKMAHEFEHPFLEKLIFAGQRPPFVECDDYFLKRYKNQFQYYLDISMKSIINTRDIGEGDDDDEINSVPFKCTLCSYEYDEENNNENTNGFIDEADKIYNRSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNSNSNNNNNNNFYDKKYFKNNYFQHLLSKHLNQIKAKGIQDTNVYNDEANIPLGSKKCDHLECSEIILKNEFTKHIKKLHHHHKDEDIDICPRCKILKKSIQKRIVKFSKKKQEKDDDNNSKPVSNKVATISHNPSPNNIDKDINNNNNNKNNKNNTNNLENDNNDNSSNNNYLENEEEPEIVFQDIKPNNNNNNNNNNNNNDDNNNDNNDNNDNENNNDNNNDNENSNNNNNNS", "length": 901 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86BK9-1", "protein_name": "Mediator of RNA polymerase II transcription subunit 22", "gene_name": "Dmel\\CG32971", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDSKDEALLKSFKTQLKDNVLSMLLNFEELLKLVSPRTPGQITNDTEQELNAFEMQVRAGNFVRAGEALIKLVHDVKEYQIIYDYSNIEEEMDRQSEAMHAKVTEYDQTLIKMVKDLEEELSELEYEYYEKSGGPDLDSKDLLV", "length": 145 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86IJ5-1", "protein_name": "Uncharacterized protein DDB_G0272718", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MPPHGHHHHHHGHHGHHEHITITPVYAPPQVVQPIYAPPPVVQPVYVQPPVVYPQATIVLETGHHHGHHHHHGHHGHHDHHHHGHHGHH", "length": 89 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86IV6-1", "protein_name": "DNA replication ATP-dependent helicase/nuclease DNA2", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNFFEKKNNNNNNSSNNNNNNNNNKNNNNKNLDKNNSSDRNNNNNGDKNNLKPTQKSLIDLWFQVDDEDEEYELSSLSNDGGSSFNSFKVNNRDTSIGSDIYSKTITPSSLALSTSSLISSTLTPPTQSPPFSKKNEKTSSFLNSPSSQKSKSNNSNVKEKLSPQYSSSSQLSDFFKKKKRPLLDNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTISSLNTNSNNNSSGSSNGSSSSSSGGGNKSSNNKKQKVSQSTSSTSLKEKQSQQSILSYLNPTPSLPTPIFDKPIERSDSNLATSSFSKLNFDDIPLDDEELSQKINTPSPKLILKNTFSSTPTQKSPSLSSTPPNKIKITDKKLPNSSSSSSSPPPSSAKSKLSHRSQSSPLSPLITNLNQNKSNEFDDINFNFNIPSPLKEINNKPNIKSNSKETLTPLTQIFHSSSPPPSIIIESSPSVCFSPTPTKNQSPTLSNLSPTFSFLSDTSPVKSPSQLFEFTFDDPLSPKLISSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTNTFISKNNLINLFNEQSNQENVSTTTTTTTTTTTSTSTNNNNNNRYERVLIINVFYEVTQIFNNSNDKIHKKTLSGFSESIGESREIQLLDEWIYTPVRPGDIVNVIGEFDDNGEIIINNIQNLLILHPDILITGTELGGSLTCTRRSVLKEQIRVGNSNSSTVPIFGSIVHEIFQECLKNNRFHLDDINTFKQEIIGKSTFQLGLSSLGETQDTALNHLENWLPTIDKFAKTFILPSSSSSSASSLKKNLIEINSEKWHLSISKILEIEENIWSLMYGLKGKIDSSLEIKLVKQQQDEKQSKQSKQSKKKKQQTTSPNNNNNNNNNNNNNNNNNNNNNNNNNNGPTTCYLNVPFEIKTGKPYQIPYISHSSQVLIYTLLMNDRYDQDIEMGILYYLKSQEFKSVGLNYGLLHPILFERNQIRSLIVSRNLLAYFLNLNSQPLLKPNPILPEMLRDYHSCTKCYSIDPCVLYHKAIENGDQFTSSLGDLFLEKTNHLSSIHINYLKNWNKIISLEYSIKNNKRKLIWNKSRKFGEKNNSCIGELILISEEYSEITETFSYRFRVNPDKLLNSSISEGDYLLISVEDKYYGMGSGQLSNIINDIITITCREKLSEPPSLLSDYTTPNCNNNDPSYFGNYRNKPLIYIEYEDADQQQQQQQQQQQQQQQQQQQQQQQSQKQQKQKQPNFTQLRGLNNYVNNSKLTPFKWRVDIDEQLSGLSIVKSNLFNLFLKENQKLRSLIVDLEAPIFDKLEQENYWKSIDFQNDYPLLNIDQRNAIIKTLSAKDYSLIHGMPGTGKTTLVISLIHILWRLGKKVLITSFTHTSLDHLLLKFNKQYPNIEMLRVASSLNQIDPSLHRFTLEKQSFGNITQSKQYLERQQLVATSCLGINHQCLLKMQFDYCIIDEASILSQPISMGPILKCKSFVLVGDHHQLPPIVNNKEAGKLGLDISLFKQLSTSHPSSVSNLYHQYRMCNSIMSLSNHLIYNNRLVCGNQSISNLSLQTNYYHNNNNTTHIDLLDHINNWPQIICNPNSSVIFVNTDQLNNSTESSNGDLFYNQTEANIVAILTNCLINKLNINQSQIGIITPIRFQLNFIKKSILKYLSIENNNNNNNNNNNSNNNNNNSNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNQNNNQNYLKKIENLDILTIDKFQGKDKDCIIISFVRSNEKKEIGELIKDWKRMNVAFTRAKKKLIFVGSKSSLSKFPFFLDFFEFLDSKNWIYNLNNKIQF", "length": 1838 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86JI5-1", "protein_name": "Probable polyketide synthase 5", "gene_name": "pks5", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDMKLNDIENENFINQMKGVAIVGIGFRIPSGNSENSISSPDDLFNNLKNGFDGVSSTSERWSDNYHKLGEISSPNAGLLPLNEWKSFDPLFFGINPSDAHHIDPQQRLLLKCTWEALEDASIDPISIRGTNTSVFIGSSTIDYLHANKHPDLILKNAIGFSPSTLSNRISYCFDIHGPSLSIDTACSSSMNAVTQGYHSILNGTSNMSIVGGVNFVIDVETIKGFSYLNMLSKTHGKCKAFDESGDGFTRGECAGVVVLKKLDDAIRDGNRIYCIINGISSNIDGNGIADKANFYSPSKQSQFNNINLAFKSTNGKISVNDIQYIEAHGTGTKTGDPIETEAISMAFKNRDKSTPILIGSIKSNIGHCEAGSGVVSLIKCCLMFKYQCFLPNIHFKNPNPLIKFNEWNLKVVTSPIPFNRNNEKSVSMMINNFGVTGSNCCLLISEFKKQDYESYENNIGSINKNILVPFSANSPKSLDQYQSKIKNIINNQFNFIDFANNQIYSKSNYLYQRSVVIANNSNDLVNKILNKKHIQTKNPIISNMSFKGKNPITIFVFSGQGSQYPKMALELYNNEVIFKKSIDLIDSKLSKYYGYSVLEKLRSIGDDDTTSIHDPTIAQPAMCMFSVSLFELYKHWGVNPSFILGHSLGEIPTSYCSGMIDLDTFCYTVYQRSIAQTKTHGNGRMLSINISDEEFKSMYSQKYPQIEIACYNSPQSIVVAGNESILNEISKELKEKEIFTAMLGSLSSFHTSSQQCTKDSILQLNIESKKSKVPTFSTVTTNLFNESDPFNSQYVYDNIINPVKFTQTISNIYKHIESNQLDNDIVFIEIAPHPTLSFYIKQMVPSSLNESVSVYSALHKKKNDVEEFQQTISNLYCQNGYNINFKCQFNNKKSNQKINLPLYQWDDELYFAQTQVLEQHRKEGPPIDHLGLSNSYYSPFKNSYRTFIDIKNKPFQYLKGHMVKGKYYFPGCGYIDNIIQLYKNQDIFISFIEFKTPLILIEGINQCLQTNIQQTGKSEYRAQFHFKDQKSNEWIQSSNANFQLLDHTIEMPPKYNIEEIIKNKCTLARLTKNEIYTHIKSKTGLNYTAMFQGATECYIGVDCTLSVVSIESQTNSFLNIPILDSVFHGNISLINDQCQIVFDKVHGLKYYSSNIPNDYKDKSVYVYAKLKSKTSDSYSASFTVLLSDGTVVYEIDEAFSKSLIPIKELLKIEYPNDELFSINLQPKDSPIPAPSTFKSLIYENDRFNAEPPMVENLFQYISTIFYKNIINRCPEINIDIIKSLSIDEIISNFSKISKHERLFKYVFETIKENGILNSLEEKDDTYFVFNEVLIKSSRVISKLLFPLENDNDNEDTPQLLFQNGLMDKVYKCRYLKNKNQMIAHIIKHSIKEIINNNIIIRILEFGGGTASLSVEVIEEIVTLLQENPNYQVEIEYTWSDISPAFIVDTKNKINKIIKGAGITNGLNVIYHPLTIDESLVELQSIKPSYYDFVIMSNVLHVVKDIKQAVEQMYQLLIPNGQLLFVEPPYKSIICDSLFGSFEQWWAFTDTDIRKDHCCLSQDGWYKLLKWSNFESIEMSTESKFMGSVIQAQKPSFTSLINQQPKYDNIIIFGNNCPNFIDNIKPFSNFNEFIQIETIQEFDQLINKSTITNDSIIYFIKSINQLSLDNYKQATLEYIEINQKLLQINSLCKHVLIVNDSRKTNYLASSIVGAARYFDEFQQLKLHTLDFDYDSTQNYLISKNNKMVQFINNLIDSKTNVHKEMIIINNKVYYEIVQKEKNLKLKYNSESFEQQDNLMCSLSPNLEYQLQSKQIKLRDNQVEVKTIATGINNKDYLVYSGLEGSVNSNTPQFGYEFSGIITRVGNNVKDYKVGDNVFGLSNSCTSSNIIVNHERIQIKPSNISHIEAASIPIDYLTSFMSLFNVGCLNIEDNESILIHLGSDSFGLSTFEILKWKGFKSNLFVTVNSDEIKQYLLNNYGDLITAIYSNTDKGYVSQIKNKLIEQGSNDNGVDLILNTLPSDFMDSNFQLLAINGRIIDLSNDHLNQSEYMKNVNFTLNRGYHNFDLMSQRNSRINRSLLTISKAIENGELKLIPIKEFSNSDINDAIEFIIEENRIDKIVVSHDHEVYQELYAKFSNENDFSILKSNYQINSNNLGKNILITGQSGIILEILKWIIKYSNINTIENVIILSRSSLKWELELLINQTKLSNNNIKFHFKSVDVGDSEQVDNAINEILNENQEIINIHSIFHFAFTQIACKVQEINMKHLDISHGAKTMGAINLHNQSIKRNWKLINFVISSSIASLVGSTDQCSYVCANALLDSFSKYRVSLGLPSTSINLGAIESTGFVSKNESISVFLDGSGIIPTPINQVLGLLDLQIQNPGKFTNSMVAKFNPLNFSNNEQINLLLKMDYIFNLHSNGYTKVKESAGSKNVDELFIKKISDLFSIDESKINKDIRLIDYGADSLVIVQLKNWVDQEIGFNLITIQQLQNNTINVSIKIILNFLKKINK", "length": 2512 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KS1-1", "protein_name": "DNA cross-link repair 1 protein", "gene_name": "dclre1", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MSDDEDDINLYITRSKNNENKKTNKNRLIDNNIQKTKTTTAVLTTRTTTTTTTTTASTQLKWDYGDEDDDDYSAPKDIDEEQSSKQFNYQNNQIVVKQDHDDYSAPKDMDEEQSSRQFNYQNDQTLVKQDDDHDDYNEPKDIDSQSLIDEDCDFEFDNSDFFFDDGTTNNNDNNNKNNKNNNNNNNNNNNNNNYNNNNNKNYKRKYYQSYNNSNNINNNNNNNNDKFEKRLSDLKKTGKEEAKKRGYQVRKTPTKEKKIPPSFKVIDGTNFLVDGFQYKSEDFTHYFLTHFHSDHYVGITKTWSFGNIYCTEETGKLVSHKLGVDQRYIVKCEWNKLIEIQGVKVAFLDSNHCPGSALILFIIPLRNKDGEIIGEESILHTGDFRYNQSMNNYPLLKGRTISKLYLDNTYCDPQYVFPPQPEIIKQVASIVRKENDGETLFLFGTYVIGKERILLEIAKQEGKPVHVSNEKYAILCCLSTCLDINKFTTNELITPFRAVTMSMLSYHNMLSLLDSSNNKYKRVIGFRPTGWTQAKKSITYLNRGPTTFYSVAYSEHSSFNELRDCIDHFRPTQIIPTVDCDSPIKVKNILAHFSDLYEKKKQLTIASFFSAQPVTNFFQSFFKSKSEPIIDEDNKKLIPITTTTTTNINTLTATDTTTTKIKTSNTLIKDEFTDDLIWDCSDDLISDRKLLTQSDNSSALCKIEKEENFNDLSENNNNSNNNNNNNNNNNNNNNNNNNNNNNNNKLIIENDIKEEIIDFDDPVFISQQKWIEKQIYNNNNNSNNNNFTTPTKTNGNLSNNAKLNLTPTQTQTQTPTQNNKKQKTTNVSPTSYNSNNSSQQSGLKRSKSDPNVKKNQLQTSQPPSQSLITSFFQKCASPTSLFSATPPTPSITTTSNQSTKNKNSTTTTSTSTSNNKPFKN", "length": 920 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86KX6-1", "protein_name": "TNF receptor-associated factor family protein DDB_G0272348", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEFELEDITIEQSSFTNNNSNNNNNNNNNSNSNNNNNNNNNNINNNNNHNNNNKNNSNNKNEINNQLDIPISNLVVDKENISKKYFCTICSDLLVNSFHADKFKAVQCKNGHYTTCLNCWEKHLEKKKNCIQCGVDVESIESLSSNLLVTQKFTTFKIHCPNSFFDTIDFIKDEVNGCKEIIQINELEEHLKECQYGFISCKNCEEFSKLPFQEFTQCPDFRKNTKEQHDLICPYVKISCEYCGDIINKINKESHNANWCQEITIKCLDCHLPFKKKEINQHQKSFCPETIIQCRYSKGGCNAMIRRSKLSQHLTEGDNHHQFISNILNQQDLKINELELKNTEFCLLLNGQNKKITELEILFKELNDSILIQKQQQKQQQQQQQQQQQQQQQQQQQQQSQQQQSQQQQQSQQQQQSQQSQQNNNSNSHFINNNNNNINNVQMSDSPNGGSLPQAVYKNKWVISNYSEQEQQGISKDYIKSPLFKIGNSTFFLKWFPFGKKKLNYCSIFLYKTQDDKSIIVNYYIHLVNNQISDEVYEKRGCQKYDSENGSAGYGSSQFIKRADLLNDANGFLINDSITIEIEIFATEEILPLQS", "length": 595 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8BI41-1", "protein_name": "Syncytin-B", "gene_name": "Synb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTGFWVLCFVLFPSSLSYPESWMPLVNLTHHILRDTNSSLFSNCWVCLSTQTQRSLAVPAPLSIWTDTPMKLHLTYSVRPFSGSFSISDIERRLRLFRPLTASYSFHNPDRRAIAFLQLVSSTGIFRIITRITSVIYPHKDRFFESAQRPLWGPLFTETVLRSQAPLCISRFFKVSAYATFVGNLSASLCNYTMHISPSTSHENLDLSTTHTFKQAMKRPDAKWKNPLRFSGPPSLIFSKPAYYPCPTDIKHCHTSPATPWMHCPQAPFGTCYNLTLFEPDNSTHPVTMSVNPTHFKVKLQGHRDPYPLSHYQPLTGAALSGQYSVWENEITVQENWDITSNIFSHLLSFSYAFCLNSSGVFFLCGTSTYICLPANWSGVCTLVFQYPDIELLPNNQTVPVPLFASVLSSDSVLRPKRSPHLFPFLAGLGISSALGTGIAGLATSTLYFQQLSKVLSETLEEIAASITTLQNQIDSLAGVVLQNRRALDLITAEKGGTCLFLQEECCFYVNQSGIVRDAARKLQERASELGQHSDSWGQWPDLGRWLPWLTPFLGPLLFLFFLLTFGSCLLNCLTRFVSQRLGSFVQDTAKRHVDSILQNFQYKKLPQDSPDEDTIPT", "length": 618 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BYG0-1", "protein_name": "Tetratricopeptide repeat protein 24", "gene_name": "Ttc24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSRQYGLSDVLRALEESRKLADADRSTDQGLLGPFYNDLGMGYFQLQLFPLAVEAFLQALPLCRQPSEQATVLQNLGMTHNVLGNYWEAQEFHQKAASLHGSVGQRWEQGRSFSGLAFSLSQLGDHRAAWDSYLHALQAAQDTGDVKGQWQACEGLGAAAARLGQHDQALKYYKEALALCQHEPSSVRERLVAKLADAMRTFVAQEKIAQARFLPSAPGKLQTSRKAKTSARVQSSAEDAQESQWEGEASEGGHEKKEMEGLVNTATVLGPQRQNRATTHLPSGGPSPSGEEYPFIIAPKKLRVSRSSTWAKEALGRNFQRTRIQSGLCSIM", "length": 334 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1N8-1", "protein_name": "Alpha-defensin 22", "gene_name": "Defa22", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLVLLSALVLLAYQVQTDPIQNTDEETNTEEQPGEEDQAVSVSFGGQEGSALHEKLSRDLICLCRKRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C1P2-1", "protein_name": "Alpha-defensin 21", "gene_name": "Defa21", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTLVLLSALILLAYQVQTDPIQNTDEETNTEEQPGEDDQAVSVSFGGQEGSALHEKLSRDLICLCRNRRCNRGELFYGTCAGPFLRCCRRRR", "length": 93 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C5Y2-1", "protein_name": "Mitochondrial sheath formation-associated protein", "gene_name": "Misfa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVLGWMLFVGLATYMGTFPEAMPPTLKWKERLPGQENKARRRIQALEEELLL", "length": 53 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CDW1-1", "protein_name": "Protein FAM228A", "gene_name": "Fam228a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADTKTSKCDEHFSVEKLKEWPEPESVSLMELLAREDIDEAVHAVLFRENYVVKRLDTYLQHLAVFKERRKEMLHKKWVENVVQPLQQRITDKITSYRRPGKNQVKYEHCLKQTNKPTKVSSSCLFQKQQEFREAKGTSYQHGRGKTHDTQKEAKETEKGLSFTPFSLRPHCSSPRERQRASARLMQSKPGGRNRYKGASSEKPVFTLKSHLPKEEKTVSRSQLVFERQFRASRLSQDIKEAEKKGLVVGTGPQRPRSWAAADSVPRPSLVGRRVMTAEILGEHLVSLHQAARSGLQWP", "length": 299 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CEK3-1", "protein_name": "Serine protease inhibitor kazal-like protein, minor form", "gene_name": "Spinkl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSTWIKFLFILTLVLLPYSVFSVNIFAGPENVIKEPNCTMYKSKSECSNIAENPVCADDRNTYYNECYFCIEKVVEKLKYRYHGICIYK", "length": 90 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZP1-1", "protein_name": "TBC1 domain family member 3", "gene_name": "TBC1D3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVVEVAGSWWAQEREDIIMKYEKGHRAGLPEDKGPKPFRSYNNNVDHLGIVHETELPPLTAREAKQIRREISRKSKWVDMLGDWEKYKSSRKLIDRAYKGMPMNIRGPMWSVLLNTEEMKLKNPGRYQIMKEKGKRSSEHIQRIDRDVSGTLRKHIFFRDRYGTKQRELLHILLAYEEYNPEVGYCRDLSHIAALFLLYLPEEDAFWALVQLLASERHSLQGFHSPNGGTVQGLQDQQEHVVATSQPKTMGHQDKKDLCGQCSPLGCLIRILIDGISLGLTLRLWDVYLVEGEQALMPITRIAFKVQQKRLTKTSRCGPWARFCNRFVDTWARDEDTVLKHLRASMKKLTRKKGDLPPPAKPEQGSSASRPVPASRGGKTLCKGDRQAPPGPPARFPRPIWSASPPRAPRSSTPCPGGAVREDTYPVGTQGVPSPALAQGGPQGSWRFLQWNSMPRLPTDLDVEGPWFRHYDFRQSCWVRAISQEDQLAPCWQAEHPAERVRSAFAAPSTDSDQGTPFRARDEQQCAPTSGPCLCGLHLESSQFPPGF", "length": 549 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K072-1", "protein_name": "Receptor expression-enhancing protein 4", "gene_name": "Reep4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSWMICRLVVLIFGMLYPAYASYKAVKSKNIREYVRWMMYWIVFAIFMAAETFTDIFISWFPFYYEFKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDACIVQAKERSYETMLSFGKRSLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSIPDTPVPTYQDPLYLEDQVPRRRPPIGYRPGGLQGSDTEDECWSDNEIVPQPPVRPREKPLGRSQSLRVVKRKPLTREGTSRSLKVRTRKKAMPSDMDS", "length": 257 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K4Q7-1", "protein_name": "Ceramide kinase", "gene_name": "Cerk", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAMGAAEPLHSVLWVKRRRCAVSLEPARALLRWWRSPEPGPSAPGADARSVLVSEIIAVEEKDDCEKHASSGRWHKMENPFAFTVHRVKRVRHHRWKWARVTFWSADEQLCHLWLQTLRGLLESLTSRPKHLLVFINPFGGKGQGKRIYEKTVAPLFTLASITTEIIITEHANQAKETLYEINTDSYDGIVCVGGDGMFSEVLHGVIGRTQQSAGIDPNHPRAVLVPSTLRIGIIPAGSTDCVCYSTVGTNDAETSALHIIIGDSLAIDVSSVHYHNTLLRYSVSLLGYGFYGDLIKDSEKKRWMGLVRYDFSGLKTFLSHQYYEGTLSFLPAQHTVGSPRDNKPCRAGCFVCRQSKQQLEEEEKKALYGLENAEEMEEWQVTCGKFLAINATNMSCACPRSPGGLSPFAHLGDGSSDLILIRKCSRFNFLRFLIRHTNQEDQFDFTFVEVYRVKKFHFTSKHVEDEDNDSKEQEKQKFGKICKDRPSCTCSASRSSWNCDGEVMHSPAIEVRVHCQLVRLFARGIEEES", "length": 531 }, "evidence": [ { "id": "HGNC:19256", "url": "https://alliancegenome.org/gene/HGNC:19256#orthology", "database": "AGR" }, { "id": "MGI:2386052", "url": "https://alliancegenome.org/gene/MGI:2386052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-210", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-210#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MP30-1", "protein_name": "Uncharacterized histidine-rich protein DDB_G0274557", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MEIKYFLVLLVGFLLVLPSIVNPYRKGVTITNQQPKINIYQLDVNNPHNPNNNPHNPHNPNNNPHHPHHLHHHHHHHHHHHHHHHHHHHHHHHHHHPHHPHHHPHHHHHPHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHPHHHPHPHPHPHPHPHLHPNPHPHPHPHPHPHPHPHHHPNPNPHPHPHPHPHHHHHHQEASECLSYQGNRNRLFIKRDY", "length": 233 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8NG83-1", "protein_name": "Olfactory receptor 2M3", "gene_name": "OR2M3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENSTFNSDFILLGIFNHSPTHTFLFFLVLAIFSVAFMGNSVMVLLIYLDTQLHTPMYLLLSQLSLMDLMLICTTVPKMAFNYLSGSKSISMAGCATQIFFYTSLLGSECFLLAVMAYDRYTAICHPLRYTNLMSPKICGLMTAFSWILGSTDGIIDVVATFSFSYCGSREIAHFFCDFPSLLILSCSDTSIFEKILFICCIVMIVFPVAIIIASYARVILAVIHMGSGEGRRKAFTTCSSHLLVVGMYYGAALFMYIRPTSDRSPTQDKMVSVFYTILTPMLNPLIYSLRNKEVTRAFMKILGKGKSGE", "length": 312 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NGV6-1", "protein_name": "Olfactory receptor 5H6", "gene_name": "OR5H6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLYLCFIFQRTCSEEMEEENATLLTEFVLTGFLHQPDCKIPLFLAFLVIYLITIMGNLGLIVLIWKDPHLHIPMYLFLGSLAFVDASLSSTVTPKMLINFLAKSKMISLSECMVQFFSLVTTVTTECFLLATMAYDRYVAICKALLYPVIMTNELCIQLLVLSFIGGLLHALIHEAFSFRLTFCNSNIIQHFYCDIIPLLKISCTDSSINFLMVFIFAGSVQVFTIGTILISYTIILFTILEKKSIKGIRKAVSTCGAHLLSVSLYYGPLTFKYLGSASPQADDQDMMESLFYTVIVPLLNPMIYSLRNKQVIASFTKMFKSNV", "length": 325 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R264-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r215", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNWNNIIHTIIFLSLTGPGIVGNMLIFIRHIYMPALGTEKKPVDLIVIHLAFSNMITICTTGIKDIATVFYFRNFLGDIGCKAVVFLARMARGLSICTTCLLSVVQAITISPRTSLWTKLKPQTACQIIPFILVFWIFNGLISSNLLSYIKGGSSLNRSVAATFIGHCYMLQSRHTIKWIFLSLMTLRDVIFQSLMGWSSGSMALNLYKHHKRVLYLYSSRFANNSPPEIRATWSVLILMTCFLLFYWADFILSFYHGFTVTHESILLNIKVFLELGYVSFSPYVLISRYIHPPNVFHAH", "length": 300 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R272-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r220", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLQFIKKTIFLFMTMVGILGNMSVSVHYMFSWWGSPEKKPIHLILTHLTFTNIILLLAKGLQKTIIVFGLRNFLDDIGCKIIVYLERVARGLSICTSSVLTVVQAIIISPRASGWRRLRPKSAWHILPFFSFFWILNAFISVNLIHSIRSKGMNTSQHKNSDDYCYLTPESQKIKWIVLPLMVLRDAVFQGAMGGASGYMVFLLHKHHQHVLYLQNSKLLYRTPPELRAAQSVLLLMLCFLFFYWTDCALSLFLSLSLGDSSLMINIQGFLTLGYAIFSPFVLIQRDGLIPVCWHAQ", "length": 298 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R278-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r213", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALRNYIQINTPWCMCLFVTPLTPCLPEYWDPDSLRVEGPTESSLRHNTASCTLKNTIMQNVQFRSMSSITDAFFKMYLHTRKEEMILKILKEITFLIMTVLGILGNMSVSVNYMFSWWGSPEKKPIHLILIHLIFTNIIILLVKGLPKTIAAFGLRNFLDDIGCKIIVYMERLARGLSICTSSLLTVVQAIIISPRASGWRRLRLKSAWHILLFFLFFWILNALISVNLIHSTTNTRLNVSQLKSDDNYCYFMLPIQKIKWIVLPLMVVRDAVFQGAMGGASGYVAFLLHKHHQHVLYFQNSKLLYRTPPELRAAQSVLLLMLCFVFFYWTDCAFSLFLTLSSEVNILMVNTRDFLTLGYATFSPFVLIHRDGLLVECRHVQ", "length": 384 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2A9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r229", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDFGNLAMGIVLSLQSALGILGNFSLLFYYLVLYNKERTLKIIDIILIHVFTSNSLIIFSKGLPEVLAVFGWNDLFDDVGCKLIMYVRRVSRSMSISMTCLLSVFQAITISTRNSCWKEFKEQTAKFMGLFISLCWILFMLVNMLFPVYTSTNRNSKNKTQKKDIEFCHSVGRDKMVDIMYTAFCVFPEVLFSLLIVSSSTTMIVILYGHKKRVQHILHTHASPRTSAENRATQTILILVCTFLAFYTLSSVLQGYVALSHDPSWWVMNITTIISMGFPAIGPFVMSRDFTVSRFCFTCIGNLKLP", "length": 306 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B6-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r178", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAHDKSLKTTDDMTLQILLLCQFVVGTVANVFLFLHNISPVLTGSKQRPRQLILSHMSVANALILFLTSFPDMMAFAPRNSPTHLKCKLEYFSRLVARSTNMCSTCVLSIHQFVTLVPVNRGKAILRASVPNLTSYSCYSCWFFSVLSNIYIAIKVTGPQITDNNTDSKSKLFCFTSGFSVGIFFLRIFHDGTFMSIMVWTSVSMVLLLHRHRQRMQHILTPNQDARGQAETRATHTILMLVVTFVSFYLLNFICIIFYTFSIDSRLFMSHFSKVFAAGFPTISPLLLIFRDPKYPCSVLFNC", "length": 304 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r64", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSQNKTLKTMEVLALQILLLCQVVVGTVGNIFLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLFAYSYDLIDFVPRKPPTDLKCKLAYFFNMVAQGTIMCSTCLLSTYQFVTLVPGNWARVMFREISPKVVSYCCYSCWLFSVLNNAYMPMYVSGPQKTHNDSDSKDNWICSISGVSVDMNFLRFSHDIIFIGIMAWTSVSMVIHLNRHHHRMHYLHNPNQINRGHAETKAAHTIMMLVVTFVSLYILDCICSLFHISFVESRLWLIDVIELLHLSFPTVSPFLLICRDPMGPCSLLFIVGLEIHVTVGAITEEQ", "length": 320 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2B9-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r59", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEMLALQILLLCQVVVGTVGNILLFVHNFSPVLTDSRLRPIQVILINLAVANAFMLLLLTYSHDMIDFVPRKPPTDLKCKLAYFFHMVAQGTIMCSTCVLSTYQFVTVVPGTWARVMFREISPKVVSYSCFSCWLFSVLHNAYIPMNVSGPQKTHNDSDSKGNSICSISGVNVDMHFLRFSHDIIFLGIMAWTSVSMMIHLNRHHQRMNRIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFHISFVESRLWSRHVIKVLALSFPTISPLLLIFRDPRGHCSLLFSVGLEIHVTGGVITEEQ", "length": 310 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R2C0-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r62", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVLALQILLLCHVVVGTVGNILLFVHNFSPILTDSRLRPIQVILINLAVANAFMLLLFAYSYDLTDIVPRKPPTDLKCKLAYFFHLVARGTIMCSTCVLSTYQFVTLVPGTWARVMFSEISPKVVSYCCYSCWLFSVLNNAYMLMNVSGPQKSHNDSDSKSNSICSISGVSVDMNILRFSHDIIFLSIMAWTSVSMVIHLHRHHQRMNHIHKVNQNNRGHAETRAAHTILMLVVTFVSLYILNCISILFYISFVESRLWLRYVTKLLALSFPTISPLLLIFRDSKGHCSLHIMSVWKST", "length": 300 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4R9-1", "protein_name": "Protein phosphatase 1 regulatory subunit 14C", "gene_name": "Ppp1r14c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVVTGGGEAAGGTSGGGARVFFQSPRGGTGGSRESSSHSGSSREDSAPVATVAAAGQVQQQQRRHQQGKVTVKYDRKELRKRLVLEEWIVEQLGQLYGCEEEEMPDVEIDIDDLLDADSEEERASKLQEALVDCYKPTEEFIRELLSRIRGMRKLSPPQKKSV", "length": 164 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R4V1-1", "protein_name": "NFAT activation molecule 1", "gene_name": "Nfam1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESWLLRRGARVRCLHPPSWLPAWCFLCLLPVPQTLQLTGLVSLTHTSLPIMVSLANTDVFFSCRIEDFTRLQRDLPVKLFHTDIHGRRRWEKQINCQHRPGMENHTRDCMVKLSQANTSATGIYYFIVEGEETYQSDGVVILVRDTVYQPPAFKVQEALMLGFTSLMSVLGVLGTALLLWKKKQISVLGKHTAKTCSGLKSTVGTTKPPAESVYTSLQRRETEVYACMKEETGSPVFSQSPATKEKLNRFEDDNEFNLVYENL", "length": 264 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8T277-1", "protein_name": "5'-AMP-activated protein kinase subunit gamma", "gene_name": "prkag", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MWYPGDEDEEFTSIIENIEKKETQEIKIKTEKLRQASLNQLPIEQSEGVGGGELSEYNNNTTNNNTPTNTTTTTNTNTTTMNNSNNNNERILSTSNGFDIRLPPNSIEQPSPSFISSSQDGVLTVDPLAVDGEKGNKESQSPPNGDNQILNNNNMFFKDITSLPSTDNKSSTNTNNNNNENPLKQTISSSPSKSTTTTTTSTSTTTTPSLSSLSSNNNNNSNSNNNYINHSSISTVSEGLENLNLKSGIKKIDSETEKYIEEGKQVFVNFLKGHTCYDVIPISGKVVVLDTKLAVKSAFYALEENGIKSAPLWNSEQHDFTGMITVSDFIDILLYYYKKPKSNNIFQDMGIHRIETFWREISVERPSSLISTEPETNLYDAASLLLCYKIHRLPVVDKKDTNSILHILTHSRILAFMMKSFPQLPEKLLSIPIGSLGIGTFATVVTVMTHTPLVEVLELLSEKKISAVPIIDSETSKIVDVYSKSDVTLMSKQGILSPSDLNLPVHQVLSTFTKLWQRPEQIYTCTRFDKLGDVIERCIKKRVHRLVCIDSSKKVEGILSLSDILNYLLNDVKSINH", "length": 577 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8TCT0-1", "protein_name": "Ceramide kinase", "gene_name": "CERK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGATGAAEPLQSVLWVKQQRCAVSLEPARALLRWWRSPGPGAGAPGADACSVPVSEIIAVEETDVHGKHQGSGKWQKMEKPYAFTVHCVKRARRHRWKWAQVTFWCPEEQLCHLWLQTLREMLEKLTSRPKHLLVFINPFGGKGQGKRIYERKVAPLFTLASITTDIIVTEHANQAKETLYEINIDKYDGIVCVGGDGMFSEVLHGLIGRTQRSAGVDQNHPRAVLVPSSLRIGIIPAGSTDCVCYSTVGTSDAETSALHIVVGDSLAMDVSSVHHNSTLLRYSVSLLGYGFYGDIIKDSEKKRWLGLARYDFSGLKTFLSHHCYEGTVSFLPAQHTVGSPRDRKPCRAGCFVCRQSKQQLEEEQKKALYGLEAAEDVEEWQVVCGKFLAINATNMSCACRRSPRGLSPAAHLGDGSSDLILIRKCSRFNFLRFLIRHTNQQDQFDFTFVEVYRVKKFQFTSKHMEDEDSDLKEGGKKRFGHICSSHPSCCCTVSNSSWNCDGEVLHSPAIEVRVHCQLVRLFARGIEENPKPDSHS", "length": 537 }, "evidence": [ { "id": "HGNC:19256", "url": "https://alliancegenome.org/gene/HGNC:19256#orthology", "database": "AGR" }, { "id": "MGI:2386052", "url": "https://alliancegenome.org/gene/MGI:2386052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041210-210", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-210#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VEU4-1", "protein_name": "Olfactory receptor", "gene_name": "Or14j2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIVENITTMRGFLLMGFSDNHELQILQALLFLVTYLLGSAGNVIIITITTLDPQLQSPMYYFLKHLSILDLSSLSVTVPQYVDICLTQSGYISYAQCMLQIFFFTGFAWGEVAILTVMSYDRYVAVCLPLHYEVIMGPSKCRWAVTAVWLSSVIPGTLYIASIFSIRFCGDRIIHQFFCDVPQVLKFSCSDDYLVTVGVADFLSAVAFACFIGIVNSYVHIFSTVLRMPSAESRSKVFSTCLPHLFVVLLFLSTGIFAYLNPTSDSPTALQFLVSIFYTVLPPTLNPVIYSLRNETIKSVIRKLLLSSKFTG", "length": 312 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VFX0-1", "protein_name": "Olfactory receptor", "gene_name": "Or5b101", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENRTEVRCFILVGLTNDPSLQLPLSITFLLIYIITLIGNLGLILMILLDSRLHTPMYIFLGNLSLVDFCYSSTVTPKVIAGFLTGDKIMSYNACASQMFFFANFGDVENYLLASMAYDRYVAVCKPLHYATTMTTHMCASLVIGCYICGFLSASIYTMDALSLSFCESNVIHHFFCDVLAVMIVSCSDSHVNELILIYVVSFNMFFALIIILISYMFIFTNILKIHSSAGYHKAVSTCASHFTAVSIFYGTIIFMYLQPSSSHTMDTDKIASVFYTMVICMLNPLVYSLRSKDVKSAFTKIVLRSK", "length": 307 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VY69-1", "protein_name": "Vesicle-associated membrane protein 723", "gene_name": "VAMP723", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAQQSLFYSFIARGTVILVEFTDFKGNFTSVAAQYLENLPSSNNKFTYNCDGHTFNDLVENGFTYCVVAVDSAGREIPMAFLERVKEDFYKRYGGEKAATDQANSLNKEFGSNLKEHMQYCMDHPDEISNLAKAKAQVSEVKSLMMENIEKVLARGVICEMLGSSESQPQAFYIKRTQMKRKKWFQNMKIKLIVLAIIIALILIIILSVCGGFNCGK", "length": 217 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q8VZ67-1", "protein_name": "Uncharacterized zinc finger CCHC domain-containing protein At4g19190", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGEGEGSGIRLSKRFAGGKVTGGSLEVDYKTKSGTAWSHSFLNQKPWHPLSYPNQRRKWIAEQTHAQHDRRAEEVAREFAQEQEFFKQAALISKKEREKIETMKAVSFMYVRPPGYDPESAKAAEYKDEKHKGQGSSTQDPVADDNVGSRPEESQGGGERTQERKKPRPKDVFGRALPTEEEFEVLKNAPRMETGIPGRVKPFAVEVRNVKCLRCGNFGHQSGDRDCPLKDAVMPNEELRLKRDDPLTAIIAHTDPSEPLKWELKQKPGLSPPRGGFDPDDPNQQIVAEDIFDEYGGFLEGSIPIEILKSMSSDKKRKSKKNKRHKKHSSRTVEETDESSTGSEDSREKRGSKKRKKLKKKSKKQYDSDSLSFEGSGSDSYRLSRRRHTKHVDPSASLKSEVYHQGNSHREKHYYDEKHQKRKEIVDRPSASSDDSDYYRSNSSRKKRSEDDYKSHHRERKQVHSNDPVSEKSQKQHYSESGKIQRVEKEHRYDERRHRYVDMESENRNRSEKKPRYDDRDSEKHHRSVKGKEKHVYEASDDPEEFSDRYRSTKKTESDSESNRRSRKKKHELSSEEEEGESRKHRYSTNRRRN", "length": 595 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q91V82-1", "protein_name": "Beta-defensin 8", "gene_name": "Defb8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRIHYLLFTFLLVLLSPLAAFSQKINEPVSCIRNGGICQYRCIGLRHKIGTCGSPFKCCK", "length": 60 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q923B3-1", "protein_name": "Neurotrophin receptor-interacting factor 1", "gene_name": "Nrif1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASTLPTTWPHESVKFEDVSLTFTEEEWAQLDFQQKCLYREIMMENYSNMISVEHHFSKPNVISQLEKAEDCWPMQREIPQDTLPECSWPSPDPGMNSFPSKSPLMKIEVVEVLTLNKDVAGPRNALIQSLYPEDLNPGNLKPAQQPSKRLTDTEASRQKFRHFQYEESAGPQKAMSQLRKLCHQWLQPNTRSKKQILELLVLEQFLNALPEKFRVWVESQHPEDCKAVVALLENMTSVSKDDASLACSSEATDQLKEKRKGVATLPVTFAAEVPAEEPVTFQDVAVDFNEEEWRLLGPTQKTEYHDVMLETLGNLVSVGWEPTLGNRELTPDSPIPVVKPIHDPNTNDLSRNGTQSTVFESILEDGVKEMHSIESNQVGNLQEKGHPQKKFSESSKSQDQTSRHKSQGSLNEVLPRKYVKVKQKGTGKRKGRTNTISMTRGLRIRKQQKDSVEWQGRSGSTPVTHGSSIKKQQQGSEQGKPGTSRDPITLTVPAKVYQKATGSEESIFMDSSDAMVPDVPPKIHQKGPEWHKVGESNNSMLQGSSVQNHQMESGAGRASDNSLLTHALPVKSHQKGYKEGNVQGNRNSWKHIKPHQKGSKGERVEELSTSEKHVPYVKNHLKTSERGKDREINASIKCDPYIKTYYRGSDVGRLRRANNCRKAFSLHAQQISFIKIHKGSQVCRCSECGKLFRNARYFSVHKKIHTGERPYMCMACGKAFVQSSSLTQHLRIHSGERPFECSECGRTFNDRSAISQHLRTHTGAKPYHCERCGKAFRQSSHLTRHERTHTGERPYVCIKCGKAFTQSSHLIGHQKTHGIKFKKQPKL", "length": 828 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q924S2-1", "protein_name": "Inactive 2'-5' oligoadenylate synthetase 1C", "gene_name": "Oas1c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MENGLCSIQARELDEFICDYLFPDTTFLTELRADIDSISAFLKERCFQGAAHPVRVSRVVMGGSYDEHTALKGKSEAKMVLFFNNLTSFEEQLKRRGEFVEEIQKHLCQLQQEKPFKVKFEVQSSEEPNSRSLSFKLSSPELQQEVEFDVQPAYDVLYELRNNTYAEPQFYNKVYAQLIHECTTLEKEGDFSICFTDLHQNFMRYRAPKLWNLIRLVKHWYQLCKEKLREPLPPQYALELLTVYVWEHSNKNQEKVTTAKNFRTFLELVAYYKNLRIYWTWYYDFRHQEVCAYLCRQLKKARPLILDPADPTRNVAGSDLQAWDLLAKEAQTWMQSSCFRNCDMSFVPTWDLSPERQECAFQ", "length": 362 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q925U0-1", "protein_name": "Oocyte-secreted protein 1", "gene_name": "Oosp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPFVGLLGLLLLLSFMKTCADDWTAISLQCADHWFHLRIRPTIFHNIFMEPDEVFLGIGCPVTTTWPNDTYEFIYRTYSCGIANKVLCDVTLLKTQLTYISKNASLQAEMSLSCVMHNQSPHFCEAESRGDFTGDPPGWTEDMRARRDEQTVPMVQPNLSTSSEDHHVSTEPWASETSRSEAAEVPSFMDQNFSVFHFSRM", "length": 202 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94490-1", "protein_name": "Ubiquitin conjugating enzyme E2 B", "gene_name": "ubcB", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAAHKRLQKEITDMLKTPPSWCSAHLVDDNLQKWKATVQGPEGSPFEKGVFSMDIDIPADYPFKPPTLKFTTKIYHPNIKTSDGAICAEVFSTWSPQLKILDVLTTIRSILTDPNPDNPLETEIAQQFKTDRNAFNKTAKEWTKKYAK", "length": 148 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q945S5-1", "protein_name": "Vacuolar cation/proton exchanger 4", "gene_name": "CAX4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSISTESSSNLSLLENGGGGSDKPTAETSRRVRRTVSASSLIRKRSDLKLISRVRWEFMRRILTNLQEVLLGTKLFILFPAVPLAVVAHRYDCPRAWVFALSLLGLTPLAERISFLTEQIAFHTGPTVGGLMNATCGNATEMIIAILAVGQRKMRIVKLSLLGSILSNLLFVLGTSLFLGGISNLRKHQSFDPRQGDMNSMLLYLALLCQTLPMIMRFTMEAEEYDGSDVVVLSRASSFVMLIAYLAFLIFHLFSSHLSPPPPPLPQREDVHDDDVSDKEEEGAVIGMWSAIFWLIIMTLLVALLSDYLVSTIQDAADSWGLSVGFIGIILLPIVGNAAEHAGAVIFAFRNKLDITLGIALGSATQIALFVVPVTVLVAWTMGIEMDLNFNLLETACFALSILVTSLVLQDGTSNYMKGLVLLLCYVVIAACFFVSNSPSSKLLF", "length": 446 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q96AK3-1", "protein_name": "DNA dC->dU-editing enzyme APOBEC-3D", "gene_name": "APOBEC3D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNPQIRNPMERMYRDTFYDNFENEPILYGRSYTWLCYEVKIKRGRSNLLWDTGVFRGPVLPKRQSNHRQEVYFRFENHAEMCFLSWFCGNRLPANRRFQITWFVSWNPCLPCVVKVTKFLAEHPNVTLTISAARLYYYRDRDWRWVLLRLHKAGARVKIMDYEDFAYCWENFVCNEGQPFMPWYKFDDNYASLHRTLKEILRNPMEAMYPHIFYFHFKNLLKACGRNESWLCFTMEVTKHHSAVFRKRGVFRNQVDPETHCHAERCFLSWFCDDILSPNTNYEVTWYTSWSPCPECAGEVAEFLARHSNVNLTIFTARLCYFWDTDYQEGLCSLSQEGASVKIMGYKDFVSCWKNFVYSDDEPFKPWKGLQTNFRLLKRRLREILQ", "length": 386 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99N64-1", "protein_name": "Germ cell-less protein-like 2", "gene_name": "Gmcl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVSRVLRCRDSSLLEPQPEAIAGASYIPGSRKRKRNSLEELATSSNVHGPQNQGMYPHQVLNYIYWKRVKISSNDAYQNLFLDGHDSDIKIRALGRTWCLHKVFLCQSGYFANILKGTWRESHHGVINLIIKNEDIDTRSLHFVFGALYTDADLSITPLEVPQVLAAACLLRVDRVIQQCEGIMKETINRNTVCSYYLAAETYRLKAVKTRCFEWLLCNLMVHPSVALYKEVDLKLMYLLALSSDLLVMQKEIDVYTTLKIWMFLYLNPCWNGTMKQLLQHANNWLSTHMAYVDNISFLESEEGLIFQPVFKKLRFQHIICDLTSTTILEQDRLIPMAWLSPIYKQQWLTLLRTQEYGVIGPQVINEQELEECTMRCGTMIPKDGRYTWKWSVGRLGFPLRVTFTRQCVILRQRCQRCDGSACHNHIRNVIFRITLVCFDSNKRVTFRKTTGYKILTFEYKEEQIVMKLDSDVLTFPMCIFCNFLFVNLGNAENK", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9C7P4-1", "protein_name": "Putative zinc finger CCCH domain-containing protein 9", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MADAGDNQQEAERRSDETESRSIKEPKEKEDEDENPQDQIQSKERMRQSSPYPVRPGKKDCQFYLKNGLCRYRSSCRFNHPTQRPQELPVRICKHIMDRNVAEPMYQDWRESESERRFDERTQRTFGDERTQRRYGIEYSGARPEKRSKIVPDFQMRDPRHHDTEWRFERERMERIERQRREAEENLQEQRQRDSIERQRREAEENLQEQRQRDSIERQRREAQENLQQQRQRDSIERQRREAQENLQQQRLQDMPENHNVDDQQNLQEQRRISIEKERTEARLRLEQIRPTVSFPINEFIRAVVLLRELIENWDDKAWKK", "length": 321 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9C8M4-1", "protein_name": "DNA-directed RNA polymerase subunit 12-like protein", "gene_name": "NRPB12L", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDLQQSETDDKQPEQLVIYVCGDCGQENILKRGDVFQCRDCGFRILYKKRILDKKETRIGV", "length": 61 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9CQK8-1", "protein_name": "Small proline-rich protein 2A1", "gene_name": "Sprr2a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSYYQQQCNQPCRPPPVCPPPKCPEPCPPQVWPGPCRPVMCFEPCLPSVWPGPCRPVVCYEQCPPQPWQSTCPPVQFPPCQQK", "length": 83 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWP4-1", "protein_name": "Lymphocyte antigen 6K", "gene_name": "Ly6k", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFLVALLVVLGLQLVQSNALTCHVCEAQNSYACSNPSQCPGEKKFCLLAVTRIFERFFYVSKQCTRRCPTPVVSPPSTNPPSEPKEFLIEKPMPFLFYKCCQWDSCNGEGPPTDQLLKEQPGKASGRRHRYIELLLTGFMVLTANGLSALCLL", "length": 154 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D541-1", "protein_name": "Coiled-coil domain-containing protein 7A", "gene_name": "Ccdc7a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKCAKHPSTISMKLTSVPELPYKKGLLNSSPKPKEKHNAKSKYGKNESMVLRSPPTGESIVRFALPIPLSKTKDKISADEMVRRITTNLKMVVSNLEDTYGACYDNGEKAAEKSEAEGLSIGDDVSSFLLCCSQFTSQLEEAVKEECGALESLYKWFQQQVNQMEEISKDQSNLEELQSDGKTASLNIVQIAKLARKFEDFKSRLKTRKEVMQTKNEDKEIMAETLKHYGLMEKQIEEFITSHSALESQTETESQSGTPSVTTRMARMIKIFENQSTMLEKALNDQQTIESKYKQLETDFQMLIMEKTLLEAEIRRLREIERVKSAAKEEQTKKSGKSEKKKFKEKEKNLSPNREFKSIEELLQIQKEAELLKTEKKTLQGQLKWALEEAERNKTQLEFVLHQKMEMFKEESKTKVGQSQNKSKVKIEDSKDSLPKKSDTQLGGQRKDQISSDQSKRPKKKQLADIDPSAVEDFPPETFKSFTVMPLIEEHRESISSQPKEEMAKASEQSEAEDIEGPLEIPSESSNEDDDLLPEDESPMMEQVTDVGRYKSIYISAEPIDTMSLISRTQSEMETLEAINYDNVLNEGEEQDKKIGKDSDTGRKSKRKRSSKIRKLSTHEEESDIVHYEEATKAKVPSKKRASDPYGDEAYESRGSVSKAQTYTKKQGTHQRGRGSASDAYGDEAYESRGSISKAQTYTRKQGTHQRGRGSVQEEESDTVHYEEVTRAKVPSKKQASDPYGDEAYESQGSVSKAHTHTKKQGTHQRGRGSVHEEESDTMNYEVPRKSKISSRRKGFALPITHQVEMHSSESQGSISKSNTETKKQGTHKRGRDSDADGARTPVSQGSDSKADTERKKHRSKEESTISKDSIPVLDEVQDKTFEHQESGLRLEVQAKKLTFSSQNIHNEESATDIKVEYQNVPSSSQVQLKKQKPLGGEIFTTHFVVPAESHAQLYQTHTPETQIERGTTSGTARLTTIPVEHPKKEASPDNLFPEKKLYITRAPTQTKKQYPPWDAKAETQKKTVKEVQGISEPQTKLNPTMSGIILHLDMDRVVETDLENLEETIVPHVLRSELEIGTDAKNMPETPTSREAVRTEAKGNQDVTISIAKGMKLIGKLKDQHGLSSFASKDTISPGKSLIKSSRDNQDDSLLETKPQENTSDKYHPSKTFPTKVINMLPFSEKSLGSTSANVDVAPKPVYRASRGRSRISKALQQLLKTSEHLKPTSTKNQNADLEKHLYISVRSANKHTQKDKKHGQSNNQKLKKQGALSSTKKQKHKEQPKTETIVENNDKFDDNLMMTTSSPNIKIIKELSKTLNLDGGDIELSDFVFKTASAAKKLENKGPSKTKNLNKESSRDIHILHLTTSAIRTLLLDEEAKIRSLEKKLMKQSTILQKSVSSMKKFMFEEPSRETKMKRKKREKRKIVVKSPHILPITTTQKHTIKEKSEISNLEKPIVRGTDILKKSTSARKKRVLKGKSKSATLPKKCDNFPFDLVRSSSDSSKQEVEEQPKPGNVDKKVSDDSYSPDISTTPTKKHTLKGQSKSRTIYEKGVDLPNNLVLSKSASSIQEFEEQPQPGNVDKKVSDDSYSPDISTSPTKKHTLKGQPKSENSDEKGIKRPNNLHMSASVARKRLLKALSTIP", "length": 1642 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D5R2-1", "protein_name": "WD repeat-containing protein 20", "gene_name": "Wdr20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATEGRGKETNEIKTHFTTREGLYRLLPHSEYSRPNRVPFNSQGSNPVRVSFVNLNDQTGNGNRLCFSVGRELYVYIYKGVRKAADLSKPIDKRIYKGTQPTCHDFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSDSLFLVAHSSGNMYSYNVEHTYGTTAPHYQLLKQGESFAVHNCKSKSTRDLKWTVGEGALNEFAFSPDGKFLACVSQDGFLRVFNFDSAELHGTMKSYFGGLLCLCWSPDGKYIVTGGEDDLVTVWSFLDCRVIARGRGHKSWVSVVAFDPYTTSVEESDPMEFSDSDKNFQDLLHFGRDRANSTQSRLSKQNSTDSRPVSVTYRFGSVGQDTQLCLWDLTEDILFPHQPLSRARAHANVMNATGLPAGSNGSAVTTPGNSVPPPLPRSNSLPHSAVSNAASKGSVMDGAITSGVSKFALLSLHDRKERHHEKDRKRNHSMGHISSKSSDKLNLVNKAKTDPAKTLGTSLCPRMEDVPLLEPLICKKIAHERLTVLVFLEDCIVTACQEGFICTWARPGKVSKFQP", "length": 567 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAF8-1", "protein_name": "Uncharacterized protein C4orf51 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHFLYLTPEILLPFSPLTSTEFELIRRKAQQLWQDETRWSASSMTTYSGSYREKQLDEATCNRLAQRVGQPQFEYKPTPLPGSSAYNTLPGHAGSQEAADGKGRLPDIASPSRDSPLNIKHKVAHQIWGSEVPCPTFLAYRGLRMSPCMQPKKPGFELLMSYRNRGKALLKRLQRQWDYESKLGSSEDSGTDRFSSNTSGSSGRKFK", "length": 208 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPV9-1", "protein_name": "Beta-defensin 5", "gene_name": "Defb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIHYLLFAFLLVLLSPLAGVFSKTINNPVSCCMIGGICRYLCKGNILQNGSCGVTSLNCCKRK", "length": 64 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EPX4-1", "protein_name": "P2Y purinoceptor 12", "gene_name": "P2ry12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPGANATSANTTSIPGTSTLCSRDYKITQVLFPLLYTVLFFAGLITNSLAMRIFFQIRSKSNFIIFLKNTVISDLLMILTFPFKILSDAKLGAGHLRTLVCQVTSVTFYFTMYISISFLGLITIDRYLKTTRPFKTSSPSNLLGAKILSVAIWAFMFLLSLPNMILTNRRPKDKDITKCSFLKSEFGLVWHEIVNYICQVIFWINFLIVIVCYSLITKELYRSYVRTRGSAKAPKKRVNIKVFIIIAVFFICFVPFHFARIPYTLSQTRAVFDCNAENTLFYVKESTLWLTSLNACLDPFIYFFLCKSFRNSLMSMLRCSTSGANKKKGQEGGDPSEETPM", "length": 343 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ER80-1", "protein_name": "Receptor-transporting protein 4", "gene_name": "Rtp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLFPDDFSTWEQTFQELMQEEKPGAKWSLHLDKNIVPDGAALGWRQHQQTVLGRFQCSRCCRSWTSAQVMILCHMYPDTLKSQGQARMRIFGQKCQKCFGCQFETPKFSTEIIKRILNNLVNYILQRYYGHRKIALTSNASLGEKVTLDGPHDTRNCEACSLNSHGRCALAHKVKPPRSPSPLPKSSSPSKSCPPPPQTRNTDFGNKTFQDFGNRTFQGCREPPQREIEPPLFLFLSIAAFALFSLFTR", "length": 249 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9FFP9-1", "protein_name": "Serine/threonine-protein kinase SRK2H", "gene_name": "SRK2H", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDKYEVVKDLGAGNFGVARLLRHKETKELVAMKYIERGRKIDENVAREIINHRSLRHPNIIRFKEVILTPTHLAIVMEYASGGELFERICNAGRFSEAEARYFFQQLICGVDYCHSLQICHRDLKLENTLLDGSPAPLLKICDFGYSKSSLLHSRPKSTVGTPAYIAPEVLSRREYDGKHADVWSCGVTLYVMLVGGYPFEDPDDPRNFRKTIQRIMAVQYKIPDYVHISQECRHLLSRIFVTNSAKRITLKEIKKHPWYLKNLPKELTEPAQAAYYKRETPSFSLQSVEDIMKIVGEARNPAPSSNAVKGFDDDEEDVEDEVEEEEEEEEEEEEEEEEEEDEYEKHVKEAHSCQEPPKA", "length": 360 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FLZ3-1", "protein_name": "SNF1-related protein kinase catalytic subunit alpha KIN12", "gene_name": "KIN12", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDGSSEKTTNKLVSILPNYRIGKTLGHGSFAKVKLALHVATGHKVAIKILNRSKIKNMGIEIKVQREIKILRFLMHPHIIRQYEVIETPNDIYVVMEYVKSGELFDYIVEKGKLQEDEARHLFQQIISGVEYCHRNMIVHRDLKPENVLLDSQCNIKIVDFGLSNVMHDGHFLKTSCGSPNYAAPEVISGKPYGPDVDIWSCGVILYALLCGTLPFDDENIPNVFEKIKRGMYTLPNHLSHFARDLIPRMLMVDPTMRISITEIRQHPWFNNHLPLYLSIPPLDTIDQAKKIEEEIIQNVVNIGFDRNHVVDSLANRIQNEATVAYHLILDNRNQNSVPNDPFQSKFKEISDGIFNSTLPVQNITSHVGHSFSALYGLKSNVKDDKTWTLGLQSQGSPYDIMTEIFKALQNLKICWKKIGLYNIKCRWVRSFAYYKNHTIEDECAIILPTVIKFEIQLYKVREGKYLLDILRIDGPQFIFFDLCVAFLRELGVL", "length": 494 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9FVV4-1", "protein_name": "DEAD-box ATP-dependent RNA helicase 55", "gene_name": "RH55", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MDSSPPNTIIEEAPPRFSELKPPLSEDIIEALDRSGFEVCTPVQAETIPFLCSHKDVVVDAATGSGKTLAFLLPFIEIIRRSNSYPPKPHQVMGVIISPTRELSAQIHKVARAVRLDFAKCREVEADMNTLEEEGANLLIGTPGRLSDMMKRMEFLDFRNLEILILDEADRLLDMGFQKQVNYIISRLPKQRRTGLFSATQTQAVADLAKAGLRNPYLKCEADQKSSQLVHLLIENKNKKLVVFFMTCACVDYWGLVISKIPSLKSISFFPTHGKMDQKGRDTALASFTEASSGVLLCTDVAARGLDIPGIVYIRSLAIKDREVLEKGLKAFVSFVRAYKEHQCSYIFSWKGLEIGKLAMGYGILSFPYISEVKQDRIGIVGFTPVQGITFEDIKFKNKSREKQRQQNLLARKDKLQQEKRGKRKKSSKEAVDDSNKASRKRKLTGRQRQTIQTAQDEEEMNLRL", "length": 465 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9JI02-1", "protein_name": "Secretoglobin family 2B member 20", "gene_name": "Scgb2b20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGTLLLLGLLVTGELSFQTTEACLPFFEGYASVLSGSRVWLYQELQAFNATAEEKVALEKIQDCFSEERIRNILLEPKIMEAMVASPECLSYYGLDNIRSILDYISKLLGE", "length": 112 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JJQ7-1", "protein_name": "X-linked lymphocyte-regulated 4B", "gene_name": "Xlr4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKIKGRPPKQPKVTPALPSNDSQQLHENNPGNNLALETCGESSSSHGTGGPKPGPSKKTLNERKRKYGVSVNKTVQNIEWNVDHFLKVQHERRQELYKDYSHQFLTLVMMWNIDVDQIKKQAGKLSDILDEQQKLFQQFQSIHMQKIEEFKELCDRHLKNLQAIKCCRRKAIIEEARKLMDYLEKRVTEETVHVNKQEAKDGVQSSLLSLLIS", "length": 215 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLV9-1", "protein_name": "Prolactin-2C5", "gene_name": "Prl2c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSLIQPCSWILLLLLVNSSLLWKNVASLPMCAMRNDRCFMFFEDTFELAGSLSHNISIEVSELFTEFEKHYSNVPGLRDKSPMRCHTSFLPTPENKEQARHIRYEALLKSGDMILDAWENPLDYLVSELSTIKNVPDIIISKATDIKKKINAVQNGVNALMSTMNGDEENKNPAWFLQSDNEDARIRSSYGMISCLDNDFKKVDIYLNILKCYMLKIDNC", "length": 222 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9LJY9-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 18", "gene_name": "CYP705A18", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATLISVDFQHCFMYIILLCLFSLLCYSLFFRKPKGTRVGCDLPPSPPSLPIIGHLHHLLSSLTHKSLQKLSSKYGPFLHLRIFSVPIILVSSASVAYEIFKAHDVNVSSRGAAAIDESLLFGSSSFIYAPYGDYWKFMKKIFATKLLRPQVLENSRGVRAEELKRFYRRILDKARKNENIEISKESAMLMNNILCRMSMGRSFSEENGEAERVRGLVGESYALVKKIFFAATLRRLLEKLRIPLFRKEIMGVSDRFDELLERIIVEHKDKLEKEHQVMDMMDVLLAAYRDKNAEYKITRNHIKSFFVDLFVGGTDTSVQTTQWTMAEIINNPNILQTLRKEIDSVVGKSRLIHETDIPNLPYLQAVVKEGLRLHPPGPLLIRTFQERCEMKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLSYSRSGQEDEKEQTLKYLSFGGGRRGCPGVNLGYIFVGTAIGMMVQCFDWKIEGDKVNMEETYGGMNLTMVNPLKCTPVPRTQPFSFTSNLEILSS", "length": 524 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LSY1-1", "protein_name": "SKP1-like protein 8", "gene_name": "ASK8", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSTKKIMLKSSEGKTFEIEEETARQCQTIAHMIEAECTDNVILVLKMTSEILEMVIEYCNKHHVDAANPCSDDDLEKWDKEFMEKDKSTIFALTNAANFLNNKSLLHLAGQTVADMIKGNTPKQMREFFNIENDLTPEEEAAIRRENKWAFE", "length": 152 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LTG5-1", "protein_name": "Callose synthase 4", "gene_name": "CALS4", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MNQPNRGQILQTVFSHFFPVASPDSELVPSSLHEDITPILRVAKDVEDTNPRSLFLQDLDIKSVDDSINILSGHSHALDKANELDPTSSGRDVRQFKNTILQWLEKNNESTLKARQKSSDAHEMQSFYQQYGDEGINDLLNAGAGSSSSQRTKIYQTAVVLYDVLDAVHRKANIKVAAKILESHAEVEAKNKIYVPYNILPLDPDSKNHAMMRDPKIVAVLKAIRYTSDLTWQIGHKINDDEDVLDWLKTMFRFQKDNVSNQREHLILLLANVQMRQTQRQPNLLDDRALDTVMEKLLGNYNKWCNHVGLESSLRFPKDKQQKVVQQRKLLYTGLYLLIWGEAANLRFMPECLCYIYHHMAFELFEMLESKGSKKKYKPKNPTYSGKDEDFLTKVVTPVYKTIAEEAKKSGEGKHSEWRNYDDLNEYFWSKQYLDKLGWPMKANADFFCKTSQQLGLNKSEKKPDLGDGCVGKVNFVEIRTFWHLFRSFDRMWSFYILSLQAMIIIAWNETSESGGAVFHKVLSVFITAAKLNLFQAFLDIALSWKARHSMSTHVRQRYIFKAVAAAVWVLLMPLTYAYSHTSIFIVAILIYLSPNMLPEMLLLIPSIRRTLEKSDFRPVKLIMWWSQPELYIGRGMHESAWSIYKYMMFWIVLLTSKLAFSYYVEQIKPLMGPTKEIMSVPMPGYWLPEFFPHVKNNRGVVITLWSPVILVYFMDTQIWYAIVSTLVGGLYGAFRHIGEIQTLGMLRSRFQSLPGAFNACLIPNENTKEKGIKLAFSRKCHKIPNTNGKEAKQFSQMWNTIINSFREEDLISNRELELLLMSCWAYPDLDFIRWPIFLLASKIPIAVDIAKKRNGKHRELKNILAEDNCMSCAVRECYASIKKLLNTLVTGNSDLMLITTVFTIIDTHIEKDTLLTELNLSVLPDLHGHFVKLTEYVLQNKDKDKIQIVNVLLKILEMVTKDILKEEIKRLHLLLTVKESAMDVPSNLEARRRLTFFSNSLFMEMPGAPKIQNMLSFSALTPYYSEDVLFSTFDLEKENDGVSILFYLQKIFPDEWKNFLERVKCGTEEELDAIDYLKEEIRLWASYRGQTLTKTVRGMMYYQKALELQAFFDLANERELMKGYKSAEASSSGSSLWAECQALADIKFTYVVACQQYSIHKRSGDQRAKDILTLMTTYPSLRVAYIDEVEQTHIYSKGTSENFYYSALVKAAPQTYSTDSSDSGHMLDQVIYQIKLPGPPIIGEGKPENQNNAIIFTRGEALQTIDMNQDYYIEEAFKMRNLLQEFLEKNGGVRYPTILGLREHIFTRSVSCLAWFMSNQEHSFVTIGQRVLANPLKVRFHYGHPDVFDRVFHLTRGGVSKASKVINLSEDIFAGFNSTLREGTVSHHEYIQVGKGRDVGLNQISMFEAKIANGSGEQTLSRDLYRLGHQFDFFRMLSCYFTTVGFYFCSMLTVLTVYVFLYGRLYLVLSGVEKELGNKPMMMEIILASQSFVQIVFLMAMPMIMEIGLERGFYDALFDFVLMQLQLASVFFTFQLGTKFHYYCKTLLHGGAEYRGTGRGFVVFHAKFAENYRFYSRSHFVKATELGILLLVYHIFGPTYIGLFTISIWFMVGTWLFAPFLFNPSGFEWHEIVEDWADWKKWIEYDNGGIGVPPEKSWESWWEKDIEHLQHSGKWGIVVEIFFALRFFIFQYGLVYQLSAFKNKYSSLWVFGASWLLILILLLTVTVLDYARRRLGTEFQLLFRIIKVSLFLAFMAIFITLMTCRLILPQDVFLCMLALIPTGWGLLLIAQSCKPLIQQPGIWSWVMTLAWVYDLVMGSLLFIPIAFMAWFPFISEFQTRMLFNQAFSRGLHISRILSGQRKHRSSKNKD", "length": 1871 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LU95-1", "protein_name": "Pyruvate kinase", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEMLLGGQATNGALRSKTKIVCTLGPASRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDNTGILCAVMLDTKSPVIRTGFLKEGKPIQLKQGQEITISIDYKIQGDSNTISMSYKKLAEDLKPGDVILCSDGTISLNVLSCDKYLGLVRCRCENSALLGERKNVNLPGIVVDLPTLTEKDKEDIMQWGVPNKIDIIALSFVRKGSDLIQVRKLLGEHSKSIMLMSKVENQEGVMNFDKILENSDAFMVARGDLGMEIPIEKMFLAQKTMINKANAHGKPVVTATQMLESMTVSPRPTRAEATDVANAVLDGTDCVMLSGETAAGAHPETAVLTMSRICKEAEDFIDYDILHKKTLGMVSLPLSPIESLAASAVSTARSVFASAIVVLTRGGYTAELVAKYRPSVPILSVIMPEIAECSDSVAHVARRGLIYRGIIPVVGCSARDSTEEMIRLAIGFAKTKGICKTGDSIVALHKIDGSSIVRIVSVE", "length": 497 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LX08-1", "protein_name": "Annexin D6", "gene_name": "ANN6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MASLKIPANIPLPEEDSEQLHKAFKGWGTNEGMIISILAHRNATQRSFIRAVYAANYNKDLLKELDGELSGDFERVVMLWTLDPTERDAYLANESTKLFTKNIWVLVEIACTRPSLEFFKTKQAYHVRYKTSLEEDVAYHTSGNIRKLLVPLVSTFRYDGNADEVNVKLARSEAKTLHKKITEKAYTDEDLIRILTTRSKAQINATLNHFKDKFGSSINKFLKEDSNDDYVQLLKTAIKCLTYPEKYFEKVLRRAINRMGTDEWALTRVVTTRAEVDLERIKEEYLRRNSVPLDRAIANDTSGDYKDMLLALLGHDHA", "length": 318 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LXS7-1", "protein_name": "Citrate synthase 1, peroxisomal", "gene_name": "CSY1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEISERARARLAVLNAHLTVSEPNQVLPAIEPWCTSAHITAAPHGSLKGNLKIVDERTGNEYQVPVSEHGTVKTVDLKKITTGKDDKGLNLYDPGYLNTAPVRSSISYIDGDEGILRYRGYPVEELAEKSTYTEVTYLLIYGNLPSQRQLADWEFAISQNSAVPQGVLDMIQSMPNDVHPVGALVTAMSALSIFYPDANPSLMGLGVYKSKQVRDKQIVRVLGQAPTIAAAAYLRKAGKPPVQPLSNLSYSENFLYMVESMGDRSYKPNPRLARVLDILFILQAEHEMNCSTAAARHLSSSGGDVYTAVSGGVGAIYGPLHGGAVEATINMLSEIGTVENIPEFIESVKNKKRRLSGFGHRIYKNYDPRGKVVKKLADEVFSILGRDPLVEVGDALEKAALSDEYFVKRKLYPNVDFYSGLINRAMGIPSSFTAVSRIAGYLSHWRESLDDPDTKIMRPQQVYTGAGIRHYETVRERTKL", "length": 480 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9LY06-1", "protein_name": "Glycine/proline-rich protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MITCILKISISSFIVLRIFSFLWFSRWFCCGLCGRFWFRCWFCCWFQFWFRCRFYCRFDTGFDVRFAAGFAADLTIGFTIGFDSGFATFLDVGLDDGFATGLDISFAGGFVTGFATDFDVGFDTGFTIGFDTGFDVGLPAVFSIGFDTGFAVGFAISFTVGFDAGFPTGFFVSLDVGFVADFVIGFATGIGVGFEVDFATDFDTCFATGFAVSFDVGFAGGFSIGFAADFANGFTVGFDGGFDASFFVGLDVGFVVGFVTSFAAGLDVGFAIDFATGFDTGFAFGLAFGFDVGFAAGFAVGFATGFTVVFDVGFASDFFVGLDVGFLTGFATDFDIGFVVDFDIGFATGFVVGFDDGSIVGLVVGLPASLDDGLAIDFVVGLDIGFVTGLFVGLVDGLTTDLDVGLVDGLDDGLDDGLDVDLVVVGFVVDGLAVDLDVGLGVGLTVGFVDGLDVGFDDGLDADTVDGLDVGLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDGLDVDLDDGLDVDLVDGLDIGLDDGLDVGLDDGLDFGLVDDGLVVGLFDVFVGTGLSWEIPPPGKLPPDASPLGIGSFGVGPPGASPFIASPSGEGPLSEGLLGIRSFGISPLSIRPLGISPLGISPPNIEPSKADASDADPSNAGPLGISPLSIDPPVAGASDEGPLGKLPPDLSPPGKGSSGEGPLVESPPSEGPLGVDPLGAGSLGISPLGKSPLRIRPLGISPFGKIPSNIDPSSALASDGGPPDEPASAEGSPDVGIFGISPPIIDPPVEGASDGDPPEKLSLDISPLGKGPSGVSLLGAGPPGVGPVIASPPGEGPRDAGPLGAGSLGISPLNIRRLGISPSGISPPNIDLPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGESESDGDPAGKLPLDISPLSKGPSCVSPLGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLSISPFGISPSSIDSPVAGTSIGGPPDEGASDGGPPDVGPFGISPPIIDPPGEDASDGDPPGKFPLDISPLGKCPSGVSPLGVGPPGVGPVIASPPGEGPLDAGPLGAGSLGISPLNIRRLGISPFGISPPNIDLPVAGTSIGGPLDEGASDGGPPDVGPFGISPSIIDPPGEGAFDGDPPGKLPLDISPVGKGPSGVSPPGAGPPGDGPVIASPPGESPLDAGPLGAGSLGISPFGISPPNIDWPVAGTSFGGPPGEGASNGGPLVVGPFDMPVVGASDGDALEKLPLDISLPGKGPSDVGPPGAGLPGAAPPGVDLSNVGASDRGASGEGASDGCPPDVGPFDICLLSIDPPVVGASDGGPPDEGASNGGPPDTDSFGGDPLCASPLGIDPPIVDASDGDPFGAGSPDEDPSNENASGEGASGESPPCSDVSCKGPSSAGASIGCSLDNGASTPSSPDTFLSNVFPSDKSSPDAFSPDVAALVTLPSGKDPFDISPPIVALLDVSPLGKTSSDAYSSGISPGIFEKSFPLVKLQTIEYM", "length": 1504 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9M2S0-1", "protein_name": "Probable mannose-1-phosphate guanylyltransferase 2", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKALILVGGFGTRLRPLTLSLPKPLVDFANKPMILHQIEALKAIGVDEVVLAINYEPEQLLVMSKFSNDVEATLGIKITCSQETEPLGTAGPLALARDKLVDGSGQPFFVLNSDVISDYPLEEMIAFHNAHGGEASIMVTKVDEPSKYGVVVMEEATGRVERFVEKPKLFVGNKINAGIYLLNPSVLDRIELRPTSIEKEIFPQIAEAEKLYAMLLPGFWMDIGQPRDYITGLRLYLDSLRKKSPSKLATGPHILGNVLVDETAEIGEGCLIGPNVAIGPGCVVESGVRLSHCTVMRGVHVKRYACISSSIIGWHSTVGQWARVENMSILGKNVYVCDEIYCNGGVVLHNKEIKSDILKPDIVM", "length": 364 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9NR96-1", "protein_name": "Toll-like receptor 9", "gene_name": "TLR9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGFCRSALHPLSLLVQAIMLAMTLALGTLPAFLPCELQPHGLVNCNWLFLKSVPHFSMAAPRGNVTSLSLSSNRIHHLHDSDFAHLPSLRHLNLKWNCPPVGLSPMHFPCHMTIEPSTFLAVPTLEELNLSYNNIMTVPALPKSLISLSLSHTNILMLDSASLAGLHALRFLFMDGNCYYKNPCRQALEVAPGALLGLGNLTHLSLKYNNLTVVPRNLPSSLEYLLLSYNRIVKLAPEDLANLTALRVLDVGGNCRRCDHAPNPCMECPRHFPQLHPDTFSHLSRLEGLVLKDSSLSWLNASWFRGLGNLRVLDLSENFLYKCITKTKAFQGLTQLRKLNLSFNYQKRVSFAHLSLAPSFGSLVALKELDMHGIFFRSLDETTLRPLARLPMLQTLRLQMNFINQAQLGIFRAFPGLRYVDLSDNRISGASELTATMGEADGGEKVWLQPGDLAPAPVDTPSSEDFRPNCSTLNFTLDLSRNNLVTVQPEMFAQLSHLQCLRLSHNCISQAVNGSQFLPLTGLQVLDLSHNKLDLYHEHSFTELPRLEALDLSYNSQPFGMQGVGHNFSFVAHLRTLRHLSLAHNNIHSQVSQQLCSTSLRALDFSGNALGHMWAEGDLYLHFFQGLSGLIWLDLSQNRLHTLLPQTLRNLPKSLQVLRLRDNYLAFFKWWSLHFLPKLEVLDLAGNQLKALTNGSLPAGTRLRRLDVSCNSISFVAPGFFSKAKELRELNLSANALKTVDHSWFGPLASALQILDVSANPLHCACGAAFMDFLLEVQAAVPGLPSRVKCGSPGQLQGLSIFAQDLRLCLDEALSWDCFALSLLAVALGLGVPMLHHLCGWDLWYCFHLCLAWLPWRGRQSGRDEDALPYDAFVVFDKTQSAVADWVYNELRGQLEECRGRWALRLCLEERDWLPGKTLFENLWASVYGSRKTLFVLAHTDRVSGLLRASFLLAQQRLLEDRKDVVVLVILSPDGRRSRYVRLRQRLCRQSVLLWPHQPSGQRSFWAQLGMALTRDNHHFYNRNFCQGPTAE", "length": 1032 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUG3-1", "protein_name": "Prion-like protein doppel", "gene_name": "Prnd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNRLGTWWVAILCMLLASHLSTVKARGIKHRFKWNRKVLPSSGGQITEARVAENRPGAFIKQGRKLDIDFGAEGNRYYAANYWQFPDGIYYEGCSEANVTKEMLVTSCVNATQAANQAEFSREKQDSKLHQRVLWRLIKEICSAKHCDFWLERGAALRVAVDQPAMVCLLGFVWFIVK", "length": 179 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9SAC9-1", "protein_name": "AP-1 complex subunit mu-1", "gene_name": "AP1M1", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAGAASALFLLDIKGRVLVWRDYRGDVTAAQAERFFTKLIETEGDSQSNDPVAYDNGVTYMFVQHSNIYLMIASRQNCNAASLLFFLHRVVDVFKHYFEELEEESLRDNFVVVYELLDEMMDFGYPQFTEARILSEFIKTDAYRMEVTQRPPMAVTNSVSWRSEGLKFKKNEVFLDVIESVNILVNSNGQIVRSDVVGALKMRTYLSGMPECKLGLNDRILLEAQGRAIKGKAIDLEDIKFHQCVRLARFENDRTISFIPPDGSFDLMTYRLSTQVKPLIWVEAHIERHSRSRVEMLVKARSQFKDRSYATSVEIELPVPTDAYNPDVRTSLGSAAYAPEKDALVWKIQYFYGNKEHTLKADFHLPSIAAEEATPERKAPIRVKFEIPKFIVSGIQVRYLKIIEKSGYQAHPWVRYITMAGEYELRLM", "length": 428 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SCN2-1", "protein_name": "Cytochrome P450 71B31", "gene_name": "CYP71B31", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSMFLGLLFLFPLFFILFKNLLPPRKKLPPGPTGLPLIGNLHQLGRLLHSSLHKLSLEHGPVMLVRWGVVPMAVFSSNEAAKEVLKTHDLETCNRPKLVANGLFTHGYKDIGFTQYGEEWREMKKFVGLELFSPKKHKSFRYIREEEGDLLVKKISNYAQTQTLVDLRKSLFSYTASIIFREAFGQNFRECDYINMDKLEELVQETETNVCSLAFTDFFPRGLGWLVDRISGQHSRMNIAFSKLTTFFEDVIDELLKTKQLDDHSDLVTAMLDVINRPRKFGSLKITYDHLIAMMSDVVLAGVNAGTVTMIWTMTELTRHPRVMKKLQEEIRATLGPNKERITEEDLEKVEYLNLVIKESFRLHPPAPLLLPRETMSDIEIQGYHIPKNAHVKINTYAIGRDPKRWTNPEEFNPERFLNTSINYKGQHYELLPFGAGRRNCPGMTLGITILELGLLNILYYFDWSLPSGMTIKDIDMEEDGALNIAKKVPLQLVPTLP", "length": 498 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SJ39-1", "protein_name": "Cytochrome P450, family 705, subfamily A, polypeptide 6", "gene_name": "CYP705A6", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAAILSVDFQNCFIFIVLCLFSLFCYSLFFKKPKHPRGCDLPPSPPSLPIIGHLHLLFSPLTHKSLQKLSSKYGHLLHLRIFNVPVILVSSASVAYEIFRAHDVNVSSRGVAAIDESLLFGSSGIITAPYGDYWKFMKKLIATKLLRPQSLESSRGIRGEELTRFYNSLLDKARMTESVEISTEAMKLVNNTLCRMSMGRSFSEENGEAEKIRGLVGESYALTKKMFLASLLRKPLKKLRISLFEKEIMGVSDRLDELLERILVEHEEKLHEEHQGTDMMDVLLAASGDENAEYNITRNHIKSFFVEIFIGATDTSVQTTQWTMAEILNHPNVLERLRKDIDSVVGKTRLIHETDLPNLPYLQAVVKEGLRLHPPGPLLVRTFQERCKIKGFYIPEKTTLVINAYAVMRDPDSWEDPDEFKPERFLRAPPMGGSLDKFIEFS", "length": 442 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SMT4-1", "protein_name": "Large ribosomal subunit protein eL13y", "gene_name": "RPL13C", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MKHNNVIPNGHFKKKWENYVKTSFNQPAMKTRRRIARQNKAVKIFPRPTAGPIRPVVHAQTLTYNMKVRAGKGFTLEELKAAGIPKKLAPTIGISVDHHRKNRSLEGFQTNVQRLKTYKAKLVIFPRCARTVKVGDSAQQELANATQVQVDHMPIVREMPTMELVKLTSDMKLFNAYDKIRLEGINKRHAGVRAKRAAEAEKEEKK", "length": 206 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SSB4-1", "protein_name": "26S proteasome regulatory subunit 7 homolog B", "gene_name": "RPT1B", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MIIRDIMEDPENEGPHNMRSDFEPLLSVLRLRDYETGDIIEFDSTEASEEALSDITEFGSTEASEAHFEEPYSARIKKVEKEINELAEKICNLGIKESDTGLAPPNQWDLVSDKQMMQEEQPLLVATCTQIISPNTEDAKYVVDIKKIGKYVVGLGDKASPTDIEAGMRVGVDQKKYQIQIPLPPKIDPSVTMMTVEEKPDATYSDIGGCKEQIEKIREVVELPMLHPEKFVRLGIDPPKGVLCYGPPGSGKTLVARAVANRTGACFIRVVGSELVQKYIGEGARMVRELFQMARSKKACILFFDEIDAIGGARFDDGVGSDNEVQRTMLEILYQLDGFDARGNIKVLMATNRPDILDPALLRPGRLDRKVEFCLPDLEGRTQIFKIHTRTMSCERDIRFELLAGLCPNSTGADIRSVCIEAGMYAIGARRKSVTEKDFLDAVNKVVKGYQKFSATPKYMAYYI", "length": 464 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SVM4-1", "protein_name": "Serine hydroxymethyltransferase 5", "gene_name": "SHM5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEPVYSWGNTHLDFVDPEIYDLIEKEKHRQCRGIELIAAENFTSVAVMEALGSCLTNKYSEGMPGNRYYGGTEFIDEIESLCRSRSLEAFHCNPEKWGVNVQPYSGSPANFAAYTALLQPHDRIMGLDLPSGGHITHGYYSSGGKNISATSIYFENLPYKVDSKTGYIDYDKLEEKAMDFRPKLIICGGTSYPREWDYARFRAVADKVGAFLLCDMAHNSALVAAQEAADPFEYCDVVTTSTHKSLRGPRAGMIFYRKGPKPAKKGQPEGEVYDFDAKINSAVFPALQSGPHNNKIGALAVALKQVMAPSFKVYAKQVKANAACLASYLINKGYTLVTDGTDNHLILWDLRPLGLTGNKVEKVCELCYITLNRNAVFGDTSFLAPGGVRIGTPAMTSRGLVEKDFEKIGEFLHRAVTITLDIQEQYGKVMKDFNKGLVNNKEIDEIKADVEEFTYDFDMPGFFISESRND", "length": 470 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SWH4-1", "protein_name": "Syntaxin-42", "gene_name": "SYP42", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATRNRTTVYRKHRDACKSARAPLSLSASDSFGGPVIEMVSGSFSRSNHSSYAPLNSYDPGPSSSDAFTIGMPPAWVDDSEEITFNIQKVRDKMNELAKAHSKALMPTFGDNKGIHREVEMLTHEITDLLRKSEKRLQMLSTRGPSEESNLRKNVQRSLATDLQNLSMELRRKQSTYLKRLQQQKEGQDEVDLEFNVNGKMSRLDEEDELGGMGFDEHQTIKLKEGQHVSAEREREIQQVLGSVNDLAQIMKDLSALVIDQGTIVDRIDYNVQNVSTSVEEGYKQLQKAERTQREGAMVKCATILLVLCLIMIVLLILKNILF", "length": 323 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SYN6-1", "protein_name": "SOUL heme-binding family protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEAALSIFKLSFLLTLLSGGSDLIDSLPPNCNRAECPSYEVVHAGNGYEIHRYNTTVWISTEPIQDISLNEASGNGWNQLSDYMNGNNDYHQRIEIALPYITQVSQNLSTFIVSFFVPKAFQPDPPPGNNLHVQRWDSRYVAVKQISGYVADHKIGKQVAELKASLQGTVWAKAIEKSRETGGVGSAWAYTVAQFSWPFQWSQRVNEIWFPFEMEDEETVSIVTQ", "length": 225 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9SZB4-1", "protein_name": "Putative DEAD-box ATP-dependent RNA helicase 43", "gene_name": "RH43", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEVDDGYVEYVPVEERLAQMKRKVVEEPGKGMMEHLSDKKKLMSVGELARGITYTEPLSTWWKPPLHVRKMSTKQMDLIRKQWHITVNGEDIPPPIKNFMDMKFPSPLLRMLKDKGIMHPTPIQVQGLPVVLSGRDMIGIAFTGSGKTLVFVLPMIILALQEEIMMPIAAGEGPIALVICPSRELAKQTYDVVEQFVASLVEDGYPRLRSLLCIGGVDMRSQLDVVKKGVHIVVATPGRLKDILAKKKMSLDACRLLTLDEADRLVDLGFEDDIRHVFDHFKSQRQTLLFSATMPAKIQIFATSALVKPVTVNVGRAGAANLDVIQEVEYVKQEAKIVYLLECLQKTTPPVLIFCENKADVDDIHEYLLLKGVEAVAIHGGKDQEDRDYAISLFKAGKKDVLVATDVASKGLDFPDIQHVINYDMPGEIENYVHRIGRTGRCGKTGIATTFINKNQSEITLLDLKHLLQEAKQRIPPVLAELNGPMEETETIANASGVKGCAYCGGLGHRILQCPKFEHQKSVAISSSRKDHFGSDGYRGEV", "length": 542 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0E0-1", "protein_name": "Putative ATPase, plasma membrane-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MATGDSLEDIKIEIDDDLEKIPIEEVFKKLRCSREGLSGAEGKERLKIFGPNKLENKKKEHITLRFFALMFKPLSWVIQAAAIMAMLFANGDGRQLFLGIVCLLIVNTIICYLKEDDAANVVAMARAGLSPKTKVLRDGKWSEQEASILVPGDIVSIKPGDIIPCDARLLEGDTLKVDQSALTGEFGPITKGPGEEVFSGTTCKQGEMEAVVIATGVHTFSGTTAHLVDNRTNKVGHFRKVVTEIENLCVISIAIGISIEVIVMYWIQRRNFSDVINNLLVLVIGGIPLAMPTVLYVIMVTGSLRLYRTGTITQRITAIEDMAAIDVLCSDKTGTLTLNKLSVDKNLIKVYSKDVEKEQVLLLAARASRIENRDGIDAAMVGSLADPKEARAGIREVHFNLVDKRTALTYIDGNGDWHRVSKGTPEQILDLCNARDDLRKSVHSAIRNYAERGLKSFAISWFRNTNCNTVFFFPYQLCSEHKYHIVNKLQERHICGLIGDGVDDVPSLKKADVGIAVANATEAARAASDIVLTEPGLSVIIDAVLASRAILQQMKHYTIYAVSITIRVVFGFMFIALIWKFDFSPFMVLAIALLNEETTKAITMDNVTNPSPTPDSLKLKEIFATGVVYGSYMALITVVFFWAAYRTDIFPRTFHVRDLRGNEAEMMCALYLQVSIMSQALFFVIQSRSWFFVERPGELLFLSFVTVQTIATTLAVYASWETARIEGIGWSWAGVIWLYNIIFFFPLDIMKFGIRYILTGKAQSLFDNMVHLVLNSYAKLSNGIYNHTQADHTYSLLEVSTPPSQDLRGVGWV", "length": 813 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9T0H7-1", "protein_name": "Histone H2A.8", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVCNTNILKDVSTKISAFENVRMIMVEGEMFQVARIHKQLKNRVSAHSSVGATDVVYMTSILEYLTTEVLQLAENTSKDLKVKRITPRHLQLAIRGDEELDTLIKGTIIGGSVIPHIH", "length": 118 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VNA6-1", "protein_name": "Ceramide kinase, isoform B", "gene_name": "Cerk", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTQTKQPAGRSSTSAGDFVAPISSTSASKFTPCSASDHNVLLNNFQLKKKSYRVLLHGQQLVWERLQKIKQSPQGNEAKAPLPPDSPAQPGGICSYGPQSHVLHLDDVVSIRSGDTKASSLKPPSPPGSERSSGCSGDVAQGKPTSQYLTINYAMRLSKSQTDCNRWELRRLTFFNSDPYIVRQWDQELQIRLHSSSPTRMRVRRLLVFINPYGGRKAGAQTYERHVRPIFQLAGVDATCITTQRANQVKDILLSHDLGVYDAVCCVGGDGTVAEVINGLIFRQMRELGLDEQRPPYIPRPALPVGVIPAGSTDTIAYSMHGTADVRTAAIHVILGQHRGLDVCSVSNGQSLLRFCASVLSYGYLGDVAAQSENYRWMGPRRYEYSGVKAFLNNRGYDAELRMLEEPDLLLTTPLEDIPQSPDSVCSLGESVPSVCYANCQRCSFASSIQEQRSSLFIQEESKEAERNQQVETEDSHLAASEAALLRPRPRPGNLRLPTGSISSMRNLGNDQWKVVRGNFFMICGANITCACARSPNGISRYSHLGDGCLDLILVKKTSLLNNVRFLLNTAGRSGDIRNLPFVEVYRTREFRFRTFSASEEDYSLAGSCQPITPPEEMTAHSSSTEFSSWNCDGEVVTDLDITMRSHCQLIEVFMRGPHSYSKPLKGGTTPTTPASSSDNVYCCCKD", "length": 687 }, "evidence": [ { "id": "HGNC:19256", "url": "https://alliancegenome.org/gene/HGNC:19256#orthology", "database": "AGR" }, { "id": "MGI:2386052", "url": "https://alliancegenome.org/gene/MGI:2386052#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VXF6-1", "protein_name": "Calnexin 14D", "gene_name": "Cnx14D", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAWKMLFAILLLLSAAKTGYLAPESENSVEDVQIEPGAIYGDEKFAYKSPVIDAEKFYFADHFDDVEASRKRWVLSQAKKNDIADEIAKYDGIWNWESPQRIFWANDLGLVLKSKAKHAAIAAPFRQPFDFKSNKPLVVQYELTLQEGQDCGGSYLKLLSAGKGTEQLNRFNDKTPYTIMFGPDKCGNNLKMHFIFRHVNPLNGNITEKHCKKPNARLGVPFTDKLPHLYQLVVRPDNSFEIRLDHKIIKEGSLLTDFVPPVNPPAEIDDPNDHKPESWDERKKIPDPNAHKPEDWDEDAPPHLPDTDAVMPNGWLEDEPDMIFDPTAIEPEDWNSEIDGEWEAPLVENPVCKKAPGCGKWKAPLIPNPNYKGKWSAPMIENPNNQGKWAPRKIANPDFFEDLKPFQMTPINAVGLELWSMSSDILFDNLIITDDVELARDFAANSFDIKRLYIDRESFGNKVVELARANRAIWGIVIVAIAVPVAITIFCKFGLGPSRVAAAKKAAAAAAKKTDDPQPDDDLGAEEEEKLEKGKKEEEKKEEEEEEEKEENKEEKKEEEKDDEKEMKDCEEEEDDEEKDDEEKTDERAAGDTNKESTPLSASPKKNQKSYLDNNEDEEDTLKNKEPTPKKRKRKALKE", "length": 639 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W240-1", "protein_name": "K Homology domain-containing protein", "gene_name": "cg3927", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METPSELTEKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIPGKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAIGAIRNRAPKYNNQIRRVTENPREVAYMEEVEYDYDEHLMFCSPVVRL", "length": 270 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W4G6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2861", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDYEIIEFVRRHISHIDISAETRMRYPDPISNNNFDWNSIGLGEQEDAIGQDQQSQALNENANNVSPDVPPSTIAEPTLEPSTIEGNQGQNPRIISSMPDMMPMANSFNPLININQEAGVVINTGINSIDNGLPSTYSEHISQPTNTESTRNMNSSIFDIPSDLDNNSSNESGDEVTQPTAKQSKINANFVCKIESDTNMDKLPTTSNNTNDKPPNNTDSDSDIISISDLIEDLNLDFNQLPITSCDVETHPADTQSNIDANLPYDLISAINMDFVNPANRTYMSAANSTRGTAYKIRKPRTVKRIIKAPSKSNIGKLLREAAKKENAAAGTQRPKKATSTITSSVQNFPNPNNWPACPFPMQNGTMPADEPNDLMPTVSQSLTVPAAQNRPIQTIGKIIKPPVKRTYTKRANKTNNTNIPNKNSTGVIQSNGVAPTIRQGLVEPGGTNILMPWNRQIPMVSVAENPRVQTIDKIIVPPPKRTYKKRVNKTVNTNQSSESAVGDGAPSAPIQSIPKVRKPRGPGKKTAKMVPGQESQQDIPLGVPPNGEAPQTSSQAPVPRVKRAYRKRANNTNNTNILNVNSTGVMESNGGGPTIPNSQQIPNVAVVLNLPIQPIKPKAPRKPRAKKVCNQQPGTDIPFGVSAQGQTAQIKPKPKPRAPRVPKEPKAPKEPKAPKVPKAPRVPKAPRVPKAPRVPKAPRVPKPPKEPKPPKEPKPPKQPKAPRVPKEPKPPKVPKEPKAPRAPRAPRVPKAPKEPKVPKIPKNPRVPKAPRQPKASMNKIQNTVKVPLPIEPVPLETPTYINPINTPVQSTVGEILALGSMPPISPIKFPVLFDEHAAQHTVANSNMPQSSLPTLDIPQLPTRNNKQPSTKSAEDTEILGLGKNKNAMKSDGRIKQGRVSKPSLRFSPSSSSLRPVVRSLSSSSSSSSSWSSCTTCSTCSSCSTCSSSSDSSQSSRSRNRKRRSPKVPIPHKLFESNGEINFQLGQPTRLESPSPPPPVPMQACGTFEEHLTDLTLVRVHAISPLRSPTYDFDFDLPEPMLSEESSSSSSESNDESNVNCQMAPNSQNVSMHFLKVMVFYNCYVLFQQLEKKHQSLFEESSSSSSSESNDETNVNCQMTPNSQNQKKLQSAPIREPSPDQPPEAASRSSNGGTIGPCNLKAFRRDFMISNAENTGFTNPSELNLKKCATKVCTPMERNSGSQLPIQNRFILPNSNKEEGKMNVEPVMPKHKPSRIPIRTKTPIALNLMKEPEDNARKPKNILKPFFSNADVNPCSSTDYEPNFKPCESPLPAKQNDFKLINKDKKSWVSHYQEQESQELKENSFFYAKFNLPNIPKKSFKDSKANAERRCTKTFEDVRKEAQQSRYTKAINKRQNKKAMLESALGNAITEDPTVNCNLADNPNDQVEMPRNPDIVEPTVKPVKFKAFVSASIKPKSSKKRKLMNSASNSKLFKFKIFESEVNKDENEEEDVIPDNLIIPVKRKQNISELLDMQPSTSKAAATITSQPKIAQLKRMPSKLLNEKMKSYAKKRSNDDENKDTKNTGMHMHRYKIPKLSANKPQNTSTTQSPTRGFSRLPGMYQEPNFQNAQHPFSTRGYYPYQRAYPLHRPTSQYHMNQPQPLRLHHSMYVDAEPSFESVFPAPRYQPYNINPSMRHHYSYPGEPSPSTYPMGGIPFQNNNTLYPPMRNDLCYPRGRLNYPVRNLPPMNSQGTYPPNYPQNFLPNYPPSRQFLLSMQRLADINKQIASGSIESVGGFIQMAYAGRKYRTLKDLRERTMLSKDSLRKIFKCMCKIKRPKWRISKFYLYAYWCEISGIPQSSEFGKPLELNAAYRKVISSYAENKFLRMESLMEKTGFGKSKLKRVLKMIGRKRSTKWRLLNYRKPLIHLHRSQDM", "length": 1893 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W6A5-1", "protein_name": "Green-sensitive opsin-1", "gene_name": "opn1mw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNGTEGSNFYIPMSNRTGLVRSPYDYTQYYLAEPWKFKALAFYMFLLIIFGFPINVLTLVVTAQHKKLRQPLNYILVNLAFAGTIMVIFGFTVSFYCSLVGYMALGPLGCVMEGFFATLGGQVALWSLVVLAIERYIVVCKPMGSFKFSANHAMAGIAFTWFMACSCAVPPLFGWSRYLPEGMQTSCGPDYYTLNPEYNNESYVMYMFSCHFCIPVTTIFFTYGSLVCTVKAAAAQQQESESTQKAEREVTRMVILMVLGFLFAWVPYASFAAWIFFNRGAAFSAQAMAVPAFFSKTSAVFNPIIYVLLNKQFRSCMLNTLFCGKSPLGDDESSSVSTSKTEVSSVSPA", "length": 349 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9XK79-1", "protein_name": "NADH-ubiquinone oxidoreductase chain 4L", "gene_name": "nad4L", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNLIDLILIAIYVIGISGLIFNKNNIINILIISELNLGTLGMLFVLASVELNDILGELSGLYILTFTAAESAIGLAIVVILYSKTGIINIRHLNKLKG", "length": 98 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9Y2B0-1", "protein_name": "Protein canopy homolog 2", "gene_name": "CNPY2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGWGWLALLLGALLGTAWARRSQDLHCGACRALVDELEWEIAQVDPKKTIQMGSFRINPDGSQSVVEVPYARSEAHLTELLEEICDRMKEYGEQIDPSTHRKNYVRVVGRNGESSELDLQGIRIDSDISGTLKFACESIVEEYEDELIEFFSREADNVKDKLCSKRTDLCDHALHISHDEL", "length": 182 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z1X0-1", "protein_name": "C-C motif chemokine 27", "gene_name": "Ccl27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEGLSPASSLPLLLLLLSPAPEAALPLPSSTSCCTQLYRQPLPSRLLRRIVHMELQEADGDCHLQAVVLHLARRSVCVHPQNRSLARWLERQGKRLQGTVPSLNLVLQKKMYSHPQQQN", "length": 120 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "S4R2L0-1", "protein_name": "Secretoglobin, family 2B, member 12", "gene_name": "Scgb2b12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGILLLLGLLITGELSFQTTEACVPFFEVYASVLSGSRVWLYHELQSFDATAEEKVALEKIQGCYREERLRNILLEPKIMEAMVASPECRSYYSLDNFRSILDFISNLLGE", "length": 112 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "W4VSP8-1", "protein_name": "Vomeronasal type-1 receptor", "gene_name": "Vmn1r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSFKNVLYFQAGLGVLANMVLLLFYIFIILGHRPKPTDLISCQLTFVHIIMVLTGGDILLTDLFELLNIENDLKCKTIFYISRVMRGLSICTTCLLSVFQAVTISPNTSLMAKFKQKLKKYMACVFLCIWSFNLAFSTNRIFYVGGFTNVSETNQMQVTKSCSLLPMNIIIRGFIFTISTSRDVFLVGVMLTTSVYMVITMFRYHRQCKYLYSISHLRESPEKRATQTIVLLVSFFVVMYWVDFIISFTSDMIWMYDPLILTVQKFMMYAYPTITPLVQISSDNRIIIMLKNLQSKHQQRFFNKDIFFSL", "length": 311 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "X1WF74-1", "protein_name": "Uncharacterized protein LOC100334758 precursor", "gene_name": "si:dkey-52p2.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARTSENMIGKVLFVLFLLSGPTSVLTDFHSLQILGTYIKGDTLFPQISFTFMLDDLTVGLYITERDEFIPRDNTTNEDETVSDMLDKIKNELQPLLKGTLIFQNSTESPQLFQIAWHCELLDNNKTGQMILKIAFSGSTTDEVSFYGNNFTCQCQNNMATVPLEYFQMQFKSIYYPVCMTTLGGYLVKRQVQVNRKVQPKVRLIKKVHPKSGGFRLSCLASEFYPYFINLTLLRDGQPVSDHEVTGGDLLPNGDGTYQMRKSLEIRADEREKHKYTCSAKHLDKNLDVDFEFDPSYPVKIVIPVVVLLSLVLVLTAVLIHKCMNKQAASPPEQQEPIEMGGRLRK", "length": 346 }, "evidence": [ { "id": "A5WVZ0", "url": "https://omabrowser.org/oma/group/A5WVZ0/", "database": "OMA" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A5WVZ0", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0" } ], "pmid": "" }, { "name": "ceramide kinase activity", "id": "GO:0001729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001729", "evidence": [ { "database": "UniProtKB", "id": "A5WVZ0", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A5WVZ0", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "ceramide metabolic process", "id": "GO:0006672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006672", "evidence": [ { "database": "UniProtKB", "id": "A5WVZ0", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 316, "end_pos": 318, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DRE-1638845", "name": "CERK phosphorylates CERA to form C1P", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, plasma membrane", "input_participant_list": [ "R-ALL-429807" ], "output_participant_list": [ "R-ALL-1638840" ], "enzyme_list": [ "A5WVZ0-1" ], "evidence": [ { "id": "R-DRE-1638845", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-1638845" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-1638840", "participant_name": "C1P [plasma membrane]", "crossref": [ { "id": "C02960", "database": "COMPOUND", "url": "" }, { "id": "16197", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-429807", "participant_name": "CERA [plasma membrane]", "crossref": [ { "id": "83273", "database": "ChEBI", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A5WVZ0", "gene_name": "cerk", "activity": [ { "ec_number": "2.7.1.138", "activity": "an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H(+).", "evidence": [ { "id": "A5WVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5WVZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVZ0" }, { "id": "PS50146", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50146" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DAGKc", "eco_id": "ECO_0000259", "start_pos": 261, "end_pos": 374, "start_aa": "Val", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "2.7.1.138", "ec_name": "an N-acylsphing-4-enine + ATP = an N-acylsphing-4-enine 1-phosphate + ADP + H(+).", "evidence": [ { "id": "2.7.1.138", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:2.7.1.138" }, { "id": "2.7.1.138", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=2.7.1.138" } 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8N7UR26-1", "uniprot_ac": "A0A8N7UR26", "uniprot_id": "A0A8N7UR26_DANRE", "mass": { "chemical_mass": 83795.0, "monoisotopic_mass": 83795.0 }, "refseq": { "ac": "XP_691749", "name": "zinc finger Y-chromosomal protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691749" }, "gene_names": [ { "name": "LOC563292", "type": "recommended", "evidence": [ { "id": "A0A8N7UR26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR26" } ] }, { "name": "LOC563292", "type": "synonym", "evidence": [ { "id": "XP_691749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691749" } ] } ], "protein_names": [ { "name": "Zinc finger Y-chromosomal protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UR26", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR26/entry#names_and_taxonomy" } ] }, { "name": "zinc finger Y-chromosomal protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_691749", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691749" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_691749.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_691749", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691749" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR26", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR26" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC563292", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR26", "locus": {} } ], "crossref": [ { "id": "A0A8N7UR26", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UR26", "database": "AlphaFoldDB", "categories": [] }, { "id": "563292", "url": "https://www.ncbi.nlm.nih.gov/gene/563292", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006794", "database": "InterPro", 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"MDEEVTRLALRSQEPKIILHGSDEGGAGDDEEEEYVVELQETVLVSEVEGEGASVQGFSSDELVIQDAVEDVVAEYVHCDDDEGVAVETCVMSLEGEEEEDGVAMAEMTEDVLVEGREQEHDSDSCGDYLMISLDDAGKMVSGDGDEVTVEGAIDDQEVEKDEDGQEVIKVYIFKADSGEDDLGETVDLGENETVALAEPVVRPLREKIYMSVGDGHHTQTDGGSKLSDEVYMEVVVGGEEPVPHDRPYDSTALSKDFMPVAWAAAYAGADEGCENRNGAASALLHIDESDALDKLNRQHGKNRRRAEPRQVQTAIIIGPYGQPLTVYPCMLCGKKFKSRGFLKRHTRNHHQDVLTRKKYQCTDCDFTTNKKASLHNHMEVHALSNKAPFECETCGKEFHQQAALFSHRLQHHHREQKTPTAIASPLPPATANKTHKCKFCDYETAEQGLLNRHLLAVHSKSFPHICVECGKGFRHPSELKKHMRTHTGEKPYSCMYCDYKSADSSNLKTHVKTKHSRELPFRCERCGQTFAEEEELTQHATTHDDARGHQCSHCDHRSSNSSDLKRHIISVHTKDYPHKCAVCAKGFHRPSELKKHSASHKAKKMHQCRHCNFKISDPFVLSRHILSVHTKEPQQTAQQQQQTPPTSPQQAPPTEKSPAPKRTIGAAQLAAPAVKKAGGAKGQRERRVYQCQYCDYSTGDASGFKRHVISIHTKDYPHRCQYCSKGFRRPSEKNQHIMRHHKDMVPAE", "length": 749, "header": "tr|A0A8N7UR26-1|A0A8N7UR26_DANRE Isoform 1 of Zinc finger Y-chromosomal protein 1 isoform X1 OS=Danio rerio OX=7955 GN=LOC563292 PE=3 SV=1 CANONICAL=A0A8N7UR26-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BI45-1", "url": 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"tr|A0A8N7UR26-1|A0A8N7UR26_DANRE Isoform 1 of Zinc finger Y-chromosomal protein 1 isoform X1 OS=Danio rerio OX=7955 GN=LOC563292 PE=3 SV=1 CANONICAL=A0A8N7UR26-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:563292", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563292", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR26", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR26" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR26", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR26" } ], "pmid": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVD8-1", "uniprot_ac": "A0A8N7UVD8", "uniprot_id": "A0A8N7UVD8_DANRE", "mass": { "chemical_mass": 167322.0, "monoisotopic_mass": 167322.0 }, "refseq": { "ac": "XP_693816", "name": "transmembrane protein 131-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693816" }, "gene_names": [ { "name": "tmem131l", "type": "recommended", "evidence": [ { "id": "A0A8N7UVD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8" } ] }, { "name": "tmem131l", "type": "synonym", "evidence": [ { "id": "XP_693816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693816" } ] } ], "protein_names": [ { "name": "Transmembrane protein 131-like isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UVD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 131-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_693816", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693816" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_693816.8. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_693816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693816" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVD8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmem131l", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-6110", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6110", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVD8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UVD8", "database": "AlphaFoldDB", "categories": [] }, { "id": "565444", "url": "https://www.ncbi.nlm.nih.gov/gene/565444", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR022113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045695", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045695", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055435", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055435", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565444", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565444", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UVD8", "url": "https://www.orthodb.org/?gene=A0A8N7UVD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22050", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22050", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22050:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22050:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12371", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12371", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19532", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19532", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24501", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24501", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_693816", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693816", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BI51", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BI51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BI51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BI51-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AI58", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AI58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AI58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AI58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVD8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JM93", "url": "https://www.uniprot.org/uniprotkb/A0AC58JM93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JM93-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JM93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-6110", "url": "https://zfin.org/ZDB-GENE-030131-6110", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASQRDFTHRKTWINVLLRLLQLLLLYIQHGGAQFQALTQMSSVVEVWQAEDADFFVPSQAEEQHSENVREESSSFYVQESGRQLLFQPPTLDFGPQPVGLPRAETVYIHNPSPELPVSLLSVFTSSRHFHMPSFHRRVIPPRGRTSFKIIFLPTVEGNEEISLFINTSTHGLLSYQVFGVGVHGESVKDAHRKDSVLIFPHIQSINLTQSQEDASNITILGLLLDCSLPKIFYNQPQGWCLVSEEGRIALQISLSERGERPTHLDKLKPYVLENIVVLLVLPPPEDAVSDPKIGVFMLNSGVKKLFVKEIQLLSRTDSNVELTEVLLKPSATNFTQVASLFCRHSLTAKSKRCSSQFGLHILANRTVNLYPLLQRTHRWSDSELSPLIQIRQKQRGSEHVELWLTNPFPFSFRITNISLSQQKLFKSVNFTTSVVVSSGCWKLLSLQLLSKSLPINHRTTIILATSVGLPLELHLQTYSSSSSKQGVVIVESSEECERLCPLRMSRAGRVEWQQSLLPESSSSLWRVDSSLASALCSRWHCSKELSCRWPRLPEDHSTPLDFGATPVNDSKVKNFTLKNPTGSVISVEIRTLSSYPVPLEALDMLTKWFNISPLSVNITTTEFLLLAANHKENKRGSVLRFLLQPWESRTVSVAYQPTEHKPVTSLLLIRNNLTVFDMVLVKGLGAKEMLRVGGKLPGPAASLRFNVPQSTLMECRDGLRSSKPLFAIQKSFKVENAGELPLTVVSMNINGYKCQGYGFEVQHCGSFRVDYNSSSEITIAFTPDFTSSWVIRDLTLVTERGSFFHFTLNVTLPHHMLPLCAQVVPGPSWEESFWIITLAFTCFSLAVVCLMAFHQAQHILSEFSMPNPRSNHNSVPRENSSVNHSSSNGVSRGKGSCKNYTDTSHPSDKGKGRGSPAVANGSVRLQPSSKKSSGGSSQPPKKQTKVSLLYSRYKNSPATLAASVSATTDFCGSPTNEDKDHTFELDPEICNNNNNNNDILDEALLPVEKKEHFRESKEEKVLPAVMFPMETLLGLPENITANRVPQPAGEVMENEECKRKTNADKRDHLDEQKTERGSSQKKRAEKDAELGVSAPINKTKKNAGRSRKKAPELIPGLPENSVVMVTESEREPSRAAARTRNAKPELPKTGANTDSPLKHSGTCLGRPRRKCPERRLQWESGSDSSSSSGSVRASRGSWGSWSSASSIEGERDPNRHPCRRDNIQYNPYLKDQECYLNMNYTCKNPSMNNLYDREPYQSSEMGPVPALHHTFADVAAGVDKNIDVIGSSMMEETWSVNSVPLTNEFRYNMSESLPFVPQNPSSRYDGFPWNNMSSQCSSQYPYSDRSNYMPTGNGNYQNAFSCPESQTISHSHQPVWGENGAHDINSTWDTGSCVGSKPYFSGTRSLSPMSSLFGSIWTPQSEPYQSHFHPERSAPVSPHTPHTPISPVAPFSREPGGACPGKHFSSFNPFGPHMNLDIWNSSSNRSSNSQLSNDSGYCGDM", "length": 1502, "header": "tr|A0A8N7UVD8-1|A0A8N7UVD8_DANRE Isoform 1 of Transmembrane protein 131-like isoform X1 OS=Danio rerio OX=7955 GN=tmem131l PE=1 SV=2 CANONICAL=A0A8N7UVD8-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BI51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8/entry#A0A8M2BI51-1", "sequence": { "sequence": "MASQRDFTHRKTWINVLLRLLQLLLLYIQHGGAQFQALTQMSSVVEVWQAEDADFFVPSQAEEQHSENVREESSSFYVQESGRQLLFQPPTLDFGPQPVGLPRAETVYIHNPSPELPVSLLSVFTSSRHFHMPSFHRRVIPPRGRTSFKIIFLPTVEGNEEISLFINTSTHGLLSYQVFGVGVHGESVKDAHRKDSVLIFPHIQSINLTQSQEDASNITILGLLLDCSLPKIFYNQPQGWCLVSEEGRIALQISLSERGERPTHLDKLKPYVLENIVVLLVLPPPEDAVSDPKIGVFMLNSGVKKLFVKEIQLLSRTDSNVELTEVLLKPSATNFTQVASLFCRHSLTAKSKRCSSQFGLHILANRTVNLYPLLQRTHRWSDSELSPLIQIRQKQRGSEHVELWLTNPFPFSFRITNISLSQQKLFKSVNFTTSVVVSSGCWKLLSLQLLSKSLPINHRTTIILATSVGLPLELHLQTYSSSSSKGVVIVESSEECERLCPLRMSRAGRVEWQQSLLPESSSSLWRVDSSLASALCSRWHCSKELSCRWPRLPEDHSTPLDFGATPVNDSKVKNFTLKNPTGSVISVEIRTLSSYPVPLEALDMLTKWFNISPLSVNITTTEFLLLAANHKENKRGSVLRFLLQPWESRTVSVAYQPTEHKPVTSLLLIRNNLTVFDMVLVKGLGAKEMLRVGGKLPGPAASLRFNVPQSTLMECRDGLRSSKPLFAIQKSFKVENAGELPLTVVSMNINGYKCQGYGFEVQHCGSFRVDYNSSSEITIAFTPDFTSSWVIRDLTLVTERGSFFHFTLNVTLPHHMLPLCAQVVPGPSWEESFWIITLAFTCFSLAVVCLMAFHQAQHILSEFSMPNPRSNHNSVPRENSSVNHSSSNGVSRGKGSCKNYTDTSHPSDKGKGRGSPAVANGSVRLQPSSKKSSGGSSQPPKKQTKVSLLYSRYKNSPATLAASVSATTDFCGSPTNEDKDHTFELDPEICNNNNNNNDILDEALLPVEKKEHFRESKEEKVLPAVMFPMETLLGLPENITANRVPQPAGEVMENEECKRKTNADKRDHLDEQKTERGSSQKKRAEKDAELGVSAPINKTKKNAGRSRKKAPELIPGLPENSVVMVTESEREPSRAAARTRNAKPELPKTGANTDSPLKHSGTCLGRPRRKCPERRLQWESGSDSSSSSGSVRASRGSWGSWSSASSIEGERDPNRHPCRRDNIQYNPYLKDQECYLNMNYTCKNPSMNNLYDREPYQSSEMGPVPALHHTFADVAAGVDKNIDVIGSSMMEETWSVNSVPLTNEFRYNMSESLPFVPQNPSSRYDGFPWNNMSSQCSSQYPYSDRSNYMPTGNGNYQNAFSCPESQTISHSHQPVWGENGAHDINSTWDTGSCVGSKPYFSGTRSLSPMSSLFGSIWTPQSEPYQSHFHPERSAPVSPHTPHTPISPVAPFSREPGGACPGKHFSSFNPFGPHMNLDIWNSSSNRSSNSQLSNDSGYCGDM", "length": 1501, "header": "tr|A0A8M2BI51-1|A0A8N7UVD8_DANRE Computationally mapped isoform of Transmembrane protein 131-like isoform X1 OS=Danio rerio OX=7955 GN=tmem131l PE=1 SV=2 CANONICAL=A0A8N7UVD8-1" }, "locus": {} }, { "isoform_ac": "A0A8M3AI58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8/entry#A0A8M3AI58-1", "sequence": { "sequence": "MASQRDFTHRKTWINVLLRLLQLLLLYIQHGGAQFQALTQMSSVVEVWQAEDADFFVPSQAEEQHSENVREESSSFYVQESGRQLLFQPPTLDFGPQPVGLPRAETVYIHNPSPELPVSLLSVFTSSRHFHMPSFHRRVIPPRGRTSFKIIFLPTVEGNEEISLFINTSTHGLLSYQVFGVGVHGESVKDAHRKDSVLIFPHIQSINLTQSQEDASNITILGLLLDCSLPKIFYNQPQGWCLVSEEGRIALQISLSERGERPTHLDKLKPYVLENIVVLLVLPPPEDAVYPKIGVFMLNSGVKKLFVKEIQLLSRTDSNVELTEVLLKPSATNFTQVASLFCRHSLTAKSKRCSSQFGLHILANRTVNLYPLLQRTHRWSDSELSPLIQIRQKQRGSEHVELWLTNPFPFSFRITNISLSQQKLFKSVNFTTSVVVSSGCWKLLSLQLLSKSLPINHRTTIILATSVGLPLELHLQTYSSSSSKQGVVIVESSEECERLCPLRMSRAGRVEWQQSLLPESSSSLWRVDSSLASALCSRWHCSKELSCRWPRLPEDHSTPLDFGATPVNDSKVKNFTLKNPTGSVISVEIRTLSSYPVPLEALDMLTKWFNISPLSVNITTTEFLLLAANHKENKRGSVLRFLLQPWESRTVSVAYQPTEHKPVTSLLLIRNNLTVFDMVLVKGLGAKEMLRVGGKLPGPAASLRFNVPQSTLMECRDGLRSSKPLFAIQKSFKVENAGELPLTVVSMNINGYKCQGYGFEVQHCGSFRVDYNSSSEITIAFTPDFTSSWVIRDLTLVTERGSFFHFTLNVTLPHHMLPLCAQVVPGPSWEESFWIITLAFTCFSLAVVCLMAFHQAQHILSEFSMPNPRSNHNSVPRENSSVNHSSSNGVSRGKGSCKNYTDTSHPSDKGKGRGSPAVANGSVRLQPSSKKSSGGSSQPPKKQTKVSLLYSRYKNSPATLAASVSATTDFCGSPTNEDKDHTFELDPEICNNNNNNNDILDEALLPVEKKEHFRESKEEKVLPAVMFPMETLLGLPENITANRVPQPAGEVMENEECKRKTNADKRDHLDEQKTERGSSQKKRAEKDAELGVSAPINKTKKNAGRSRKKAPELIPGLPENSVVMVTESEREPSRAAARTRNAKPELPKTGANTDSPLKHSGTCLGRPRRKCPERRLQWESGSDSSSSSGSVRASRGSWGSWSSASSIEGERDPNRHPCRRDNIQYNPYLKDQECYLNMNYTCKNPSMNNLYDREPYQSSEMGPVPALHHTFADVAAGVDKNIDVIGSSMMEETWSVNSVPLTNEFRYNMSESLPFVPQNPSSRYDGFPWNNMSSQCSSQYPYSDRSNYMPTGNGNYQNAFSCPESQTISHSHQPVWGENGAHDINSTWDTGSCVGSKPYFSGTRSLSPMSSLFGSIWTPQSEPYQSHFHPERSAPVSPHTPHTPISPVAPFSREPGGACPGKHFSSFNPFGPHMNLDIWNSSSNRSSNSQLSNDSGYCGDM", "length": 1501, "header": "tr|A0A8M3AI58-1|A0A8N7UVD8_DANRE Computationally mapped isoform of Transmembrane protein 131-like isoform X1 OS=Danio rerio OX=7955 GN=tmem131l PE=1 SV=2 CANONICAL=A0A8N7UVD8-1" }, "locus": {} }, { "isoform_ac": "A0A8N7UVD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8/entry#A0A8N7UVD8-1", "sequence": { "sequence": "MASQRDFTHRKTWINVLLRLLQLLLLYIQHGGAQFQALTQMSSVVEVWQAEDADFFVPSQAEEQHSENVREESSSFYVQESGRQLLFQPPTLDFGPQPVGLPRAETVYIHNPSPELPVSLLSVFTSSRHFHMPSFHRRVIPPRGRTSFKIIFLPTVEGNEEISLFINTSTHGLLSYQVFGVGVHGESVKDAHRKDSVLIFPHIQSINLTQSQEDASNITILGLLLDCSLPKIFYNQPQGWCLVSEEGRIALQISLSERGERPTHLDKLKPYVLENIVVLLVLPPPEDAVSDPKIGVFMLNSGVKKLFVKEIQLLSRTDSNVELTEVLLKPSATNFTQVASLFCRHSLTAKSKRCSSQFGLHILANRTVNLYPLLQRTHRWSDSELSPLIQIRQKQRGSEHVELWLTNPFPFSFRITNISLSQQKLFKSVNFTTSVVVSSGCWKLLSLQLLSKSLPINHRTTIILATSVGLPLELHLQTYSSSSSKQGVVIVESSEECERLCPLRMSRAGRVEWQQSLLPESSSSLWRVDSSLASALCSRWHCSKELSCRWPRLPEDHSTPLDFGATPVNDSKVKNFTLKNPTGSVISVEIRTLSSYPVPLEALDMLTKWFNISPLSVNITTTEFLLLAANHKENKRGSVLRFLLQPWESRTVSVAYQPTEHKPVTSLLLIRNNLTVFDMVLVKGLGAKEMLRVGGKLPGPAASLRFNVPQSTLMECRDGLRSSKPLFAIQKSFKVENAGELPLTVVSMNINGYKCQGYGFEVQHCGSFRVDYNSSSEITIAFTPDFTSSWVIRDLTLVTERGSFFHFTLNVTLPHHMLPLCAQVVPGPSWEESFWIITLAFTCFSLAVVCLMAFHQAQHILSEFSMPNPRSNHNSVPRENSSVNHSSSNGVSRGKGSCKNYTDTSHPSDKGKGRGSPAVANGSVRLQPSSKKSSGGSSQPPKKQTKVSLLYSRYKNSPATLAASVSATTDFCGSPTNEDKDHTFELDPEICNNNNNNNDILDEALLPVEKKEHFRESKEEKVLPAVMFPMETLLGLPENITANRVPQPAGEVMENEECKRKTNADKRDHLDEQKTERGSSQKKRAEKDAELGVSAPINKTKKNAGRSRKKAPELIPGLPENSVVMVTESEREPSRAAARTRNAKPELPKTGANTDSPLKHSGTCLGRPRRKCPERRLQWESGSDSSSSSGSVRASRGSWGSWSSASSIEGERDPNRHPCRRDNIQYNPYLKDQECYLNMNYTCKNPSMNNLYDREPYQSSEMGPVPALHHTFADVAAGVDKNIDVIGSSMMEETWSVNSVPLTNEFRYNMSESLPFVPQNPSSRYDGFPWNNMSSQCSSQYPYSDRSNYMPTGNGNYQNAFSCPESQTISHSHQPVWGENGAHDINSTWDTGSCVGSKPYFSGTRSLSPMSSLFGSIWTPQSEPYQSHFHPERSAPVSPHTPHTPISPVAPFSREPGGACPGKHFSSFNPFGPHMNLDIWNSSSNRSSNSQLSNDSGYCGDM", "length": 1502, "header": "tr|A0A8N7UVD8-1|A0A8N7UVD8_DANRE Isoform 1 of Transmembrane protein 131-like isoform X1 OS=Danio rerio OX=7955 GN=tmem131l PE=1 SV=2 CANONICAL=A0A8N7UVD8-1" }, "locus": {} }, { "isoform_ac": "A0AC58JM93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8/entry#A0AC58JM93-1", "sequence": { "sequence": "MASQRDFTHRKTWINVLLRLLQLLLLYIQHGGAQFQALTQMSSVVEVWQAEDADFFVPSQAEEQHSENVREESSSFYVQESGRQLLFQPPTLDFGPQPVGLPRAETVYIHNPSPELPVSLLSVFTSSRHFHMPSFHRRVIPPRGRTSFKIIFLPTVEGNEEISLFINTSTHGLLSYQVFGVGVHGESVKDAHRKDSVLIFPHIQSINLTQSQEDASNITILGLLLDCSLPKIFYNQPQGWCLVSEEGRIALQISLSERGERPTHLDKLKPYVLENIVVLLVLPPPEDAVYPKIGVFMLNSGVKKLFVKEIQLLSRTDSNVELTEVLLKPSATNFTQVASLFCRHSLTAKSKRCSSQFGLHILANRTVNLYPLLQRTHRWSDSELSPLIQIRQKQRGSEHVELWLTNPFPFSFRITNISLSQQKLFKSVNFTTSVVVSSGCWKLLSLQLLSKSLPINHRTTIILATSVGLPLELHLQTYSSSSSKGVVIVESSEECERLCPLRMSRAGRVEWQQSLLPESSSSLWRVDSSLASALCSRWHCSKELSCRWPRLPEDHSTPLDFGATPVNDSKVKNFTLKNPTGSVISVEIRTLSSYPVPLEALDMLTKWFNISPLSVNITTTEFLLLAANHKENKRGSVLRFLLQPWESRTVSVAYQPTEHKPVTSLLLIRNNLTVFDMVLVKGLGAKEMLRVGGKLPGPAASLRFNVPQSTLMECRDGLRSSKPLFAIQKSFKVENAGELPLTVVSMNINGYKCQGYGFEVQHCGSFRVDYNSSSEITIAFTPDFTSSWVIRDLTLVTERGSFFHFTLNVTLPHHMLPLCAQVVPGPSWEESFWIITLAFTCFSLAVVCLMAFHQAQHILSEFSMPNPRSNHNSVPRENSSVNHSSSNGVSRGKGSCKNYTDTSHPSDKGKGRGSPAVANGSVRLQPSSKKSSGGSSQPPKKQTKVSLLYSRYKNSPATLAASVSATTDFCGSPTNEDKDHTFELDPEICNNNNNNNDILDEALLPVEKKEHFRESKEEKVLPAVMFPMETLLGLPENITANRVPQPAGEVMENEECKRKTNADKRDHLDEQKTERGSSQKKRAEKDAELGVSAPINKTKKNAGRSRKKAPELIPGLPENSVVMVTESEREPSRAAARTRNAKPELPKTGANTDSPLKHSGTCLGRPRRKCPERRLQWESGSDSSSSSGSVRASRGSWGSWSSASSIEGERDPNRHPCRRDNIQYNPYLKDQECYLNMNYTCKNPSMNNLYDREPYQSSEMGPVPALHHTFADVAAGVDKNIDVIGSSMMEETWSVNSVPLTNEFRYNMSESLPFVPQNPSSRYDGFPWNNMSSQCSSQYPYSDRSNYMPTGNGNYQNAFSCPESQTISHSHQPVWGENGAHDINSTWDTGSCVGSKPYFSGTRSLSPMSSLFGSIWTPQSEPYQSHFHPERSAPVSPHTPHTPISPVAPFSREPGGACPGKHFSSFNPFGPHMNLDIWNSSSNRSSNSQLSNDSGYCGDM", "length": 1500, "header": "tr|A0AC58JM93-1|A0AC58JM93_DANRE Computationally mapped isoform of Transmembrane protein 131-like isoform X4 OS=Danio rerio OX=7955 GN=tmem131l PE=1 SV=1 CANONICAL=A0A8N7UVD8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:565444", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565444", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2VDJ0-1", "protein_name": "Transmembrane protein 131-like", "gene_name": "TMEM131L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGLRRPQPGCYCRTAAAVNLLLGVFQVLLPCCRPGGAQGQAIEPLPNVVELWQAEEGELLLPTQGDSEEGLEEPSQEQSFSDKLFSGKGLHFQPSVLDFGIQFLGHPVAKILHAYNPSRDSEVVVNSVFAAAGHFHVPPVPCRVIPAMGKTSFRIIFLPTEEGSIESSLFINTSSYGVLSYHVSGIGTRRISTEGSAKQLPNAYFLLPKVQSIQLSQMQAETTNTSLLQVQLECSLHNKVCQQLKGCYLESDDVLRLQMSIMVTMENFSKEFEENTQHLLDHLSIVYVATDESETSDDSAVNMYILHSGNSLIWIQDIRHFSQRDALSLQFEPVLLPTSTTNFTKIASFTCKATSCDSGIIEDVKKTTHTPTLKACLFSSVAQGYFRMDSSATQFHIETHENTSGLWSIWYRNHFDRSVVLNDVFLSKETKHMLKILNFTGPLFLPPGCWNIFSLKLAVKDIAINLFTNVFLTTNIGAIFAIPLQIYSAPTKEGSLGFEVIAHCGMHYFMGKSKAGNPNWNGSLSLDQSTWNVDSELANKLYERWKKYKNGDVCKRNVLGTTRFAHLKKSKESESFVFFLPRLIAEPGLMLNFSATALRSRMIKYFVVQNPSSWPVSLQLLPLSLYPKPEALVHLLHRWFGTDMQMINFTTGEFQLTEACPYLGTHSEESRFGILHLHLQPLEMKRVGVVFTPADYGKVTSLILIRNNLTVIDMIGVEGFGARELLKVGGRLPGAGGSLRFKVPESTLMDCRRQLKDSKQILSITKNFKVENIGPLPITVSSLKINGYNCQGYGFEVLDCHQFSLDPNTSRDISIVFTPDFTSSWVIRDLSLVTAADLEFRFTLNVTLPHHLLPLCADVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQNASSSSQQNNGPMDVISPHSYKSNCKNFLDTYGPSDKGRGKNCLPVNTPQSRIQNAAKRSPATYGHSQKKHKCSVYYSKHKTSTAAASSTSTTTEEKQTSPLGSSLPAAKEDICTDAMRENWISLRYASGINVNLQKNLTLPKNLLNKEENTLKNTIVFSNPSSECSMKEGIQTCMFPKETDIKTSENTAEFKERELCPLKTSKKLPENHLPRNSPQYHQPDLPEISRKNNGNNQQVPVKNEVDHCENLKKVDTKPSSEKKIHKTSREDMFSEKQDIPFVEQEDPYRKKKLQEKREGNLQNLNWSKSRTCRKNKKRGVAPVSRPPEQSDLKLVCSDFERSELSSDINVRSWCIQESTREVCKADAEIASSLPAAQREAEGYYQKPEKKCVDKFCSDSSSDCGSSSGSVRASRGSWGSWSSTSSSDGDKKPMVDAQHFLPAGDSVSQNDFPSEAPISLNLSHNICNPMTVNSLPQYAEPSCPSLPAGPTGVEEDKGLYSPGDLWPTPPVCVTSSLNCTLENGVPCVIQESAPVHNSFIDWSATCEGQFSSAYCPLELNDYNAFPEENMNYANGFPCPADVQTDFIDHNSQSTWNTPPNMPAAWGHASFISSPPYLTSTRSLSPMSGLFGSIWAPQSDVYENCCPINPTTEHSTHMENQAVVCKEYYPGFNPFRAYMNLDIWTTTANRNANFPLSRDSSYCGNV", "length": 1609 }, "evidence": [ { "id": "HGNC:29146", "url": "https://alliancegenome.org/gene/HGNC:29146#orthology", "database": "AGR" }, { "id": "RGD:1583677", "url": "https://alliancegenome.org/gene/RGD:1583677#orthology", "database": "AGR" }, { "id": "MGI:2443399", "url": "https://alliancegenome.org/gene/MGI:2443399#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6110", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6110#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZRG1-1", "protein_name": "Transmembrane protein 131-like", "gene_name": "Tmem131l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGLRRPQSGAYRRTAAAVNLLLGVFQVLLSCCRPGGAQGQAFEPLPNVVELWQAEEGELLLPTQGDSEEDMEEPSQEQSFSDKLFIGKGLHFQPSVLDFGIQFLGYPAAKLLYAYNPSRDSEVVVNSVFTAARHFHVPPVHCRVIPAMGKTSFRIIFLPTEEGSFESSLFINTSSHGVFSYHVSGVGTRRASTEGSAEQLPNAHLLLPQVQSIQLSQTQAETTNTSLLRVQLECSLHNKVCQQLKSCYLGSDDTLHLEMNIIVAVENSSKQPEENTQALLDHLTIVYVATDESETSDESAVNMYVLHSGSSLIWIQDIHHFSQKNLLSLQFEPVLLSTSTTNFTKVASFTCRAGTSCDSGIVGIRRRKDTPTMKACLSSPVVQGYFRVDASTAQFHIESHKTATGVWSIWYQGHFDHSIVLKDVFVSKETKHILKVLSFRGPLFLPPGCWNIFSLKLAVKGVVLNLFTNVFLTTNTGAVFAIPLQIFSAPAKEGSLGFEVLAHCGMHYFMGKSKPETPDWERSLSLDRSTWDVDSELANKLYERWKKYKNGDVCRRNVLGMSQFAFAKKSKETEPFVSFLPRVVLEPGLVLNFSATALRNSVVKYFVVRNPSPWPVSLQLLPLSLYPRPEAAVRLLYKWFGTDMQMVNLSTGEFQLTKACPYQGEPSEESSLGALHVHLQPFDMRKVGVVFTPADYGKVTSLILIRNNLTVVDMVGVEGFGAQELLKVGGRLPGAGGSLRFKVPESTLMDCHRQLKDSKQILSITKNFKVENVGPLPITVTSLKINGYNCQGYGFEVLDCHPFSLSPNTSRDISIVFTPDFTSSWVIRELTLVTAAELEFHFTLNVTLPHHMLPLCAEVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQNGSSSPQQNGDPVDMISSHSHKSTCKNFLDTYSPSDKGRGKSCLPVGPPLSRLQNAAKRSPATYSHSQKKHKCSFYYSKQKPSASTASSANITTEEKQTVTLASSLSAAKEDLCTNILNENWASLRYASGVNGSLQRNLTLPKNVLNKEESSLKNTVVSNTSSECSMKEGIQTCMFPKETDSKISEHVAELKEQEPCPQKTSKKPPESTLPKTPPQYPQSDLPEVSRKHGNNQQVPVKNEVDSFETVKAVDTKLSSVKKTQRESPEDTCSEKQDSPSAEQDDPYRKRKLQEKREGNTQTLNWNKTRTCRKHKKRASVQAPSSPRPSEQSEQRLVCSDVRSWCAQDSTGETCKAGIEIVGDSPVRREEDSSYQKSEKKCADKFCSDSSSDCGSSSGSVRASRGSRDSWSSSSSDCDRKPVVDIQQFLPPGDGVSPRDSPSEASMPLSLPQHVCSSTDVNGLSGFTESCPGLPAAPADAGEEKGLYPPGGLWPSQPVCLTSSFNCPVENGAPGVSEEPTSIPDSSFIDWSTSCEGQFSSVYCPLELNGYNAFPEENMNYTNGFPCSSKVQTDFIGHGTSSTWNTPASMPAAWGHASLVNSPSYLTSTRSLSPMSGLFGSIWAPQSDAYENCCPVSPATEHSTHMENQVMCKEYYLGFNPFRAYMNLDIWTSTANRSANFPLSRDSGYCGNV", "length": 1596 }, "evidence": [ { "id": "HGNC:29146", "url": "https://alliancegenome.org/gene/HGNC:29146#orthology", "database": "AGR" }, { "id": "RGD:1583677", "url": "https://alliancegenome.org/gene/RGD:1583677#orthology", "database": "AGR" }, { "id": "MGI:2443399", "url": "https://alliancegenome.org/gene/MGI:2443399#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6110", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6110#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3U3D7-1", "protein_name": "Transmembrane protein 131-like", "gene_name": "Tmem131l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGLRRPQSGAYRRTAAAVNLLLGVFQVLLSCCRPGGAQGQAFEPLPNVVELWQAEEGELLLPTQGDSEEDMEEPSQEQSFSDKLFIGKGLHFQPSVLDFGIQFLGHPAAKLLYAYNPSRESEVVVNSVFTAARHFHVPPVHCRVIPAMGKASFRVIFLPTEEGSIESSLFINTSSHGVFSYHVSGVGTRRVSTEGSAEQLPNAYFLLPQVQSIQLSQTQAETTNTSLLRVQLECSLHNKVCQQLKSCSLGSDDALHLEMNIIVAVENSSKQPEENTQALLDHLSIVYVATDESDTSDESAVNMYVLHSGNSLIWIQDIHHFSQKNVLSLQFEPVLLSTSTTNFTKIASFTCKAGTSCDSGIMGLRKKKASPAMQACLSSPVVQGYFRTDASTAQFHIESHETATGVWSIWYRSHFDQSIVLKDVFVSKETKHILKVLSFRGPLFLPPGCWNIFSLKLAVKGIVLNLFTNVFLTTNTGAIFAIPLQIFSAPTKEGSLGFEVLAHCGMHYFMGKSKTENPNWERSLSLDRSTWDMDSELANKLYERWKKYKSGDACRRNVLGMSQFAFTKKSKETEPFVSFLPRVVPEPNLVLNFSATALRNSAVKYFVVRNPTPQPVSLQLLPLSLYPRPEAAVRLLHKWFGTDMQMVNLSTGEFQLTQACPYQGEPSEESSLGALHVHLQALETRRVGVVFTPADYGKVTSLILIRNNLTVVDMVGVEGFGAQELLKVGGRLPGAGGSLRFKVPESTLMDCHRQLKDSKQILSITKNFKVENIGPLPITVTSLKINGYNCQGYGFEVLDCHPFSLSPNTSRDISIVFTPDFTSSWVIRELTLVTAADLEFHFTLNVTLPHHMLPLCAEVVPGPSWEESFWRLTVFFVSLSLLGVILIAFQQAQYILMEFMKTRQRQNGSSSSQQNGDPVAMISSHPHKSTCKNFLDTYSPSDKGRGKSCLPVGPSLSRLQNAAKRSPATYGHSQKKHKCSFYYSKQKPSASAASSANVTTEEKQTVTLASSLSVAKEDICTNVLSENWVSLRYASGINGSLQKNLTLPKNVLHKEESSLKNTVVTNTPSECSMKEGVHTYMFPKETDSKISENVAELKEQEPCPQKTSKKPPESTLPKTPPQYLQSDLPEVSRKHGNKQQAPVRSEVDSFEPVRAADAEPSSVRKTQGASPEDTCSEKQDTPSAEQEDPSRKRKLQERREGSTQALNWNKTRPCRRNKKRASAQASSSPRPSEQSEQRLVCSDVRSWCAQDGAGEKCKAGTEVSGSSPERREEDSYYQKSEKKCADKFCSDSSSDCGSSSGSVRASRGSWGSWSSSSSDCDRRPVVDIQHFLPPGDGVSPQNFPSEASVPLSLPQHVCSSTDVSVLPEFTESPCPGLPATPAGAGEEKGLYPPGGLWPSQPVCLTSSFNCPVENGAPGVSQEPTSIPDSSFIDWSASCEGQFPSVYCPLELNDYNAFPEENMNYTNGFPCSSKVQTDFIGHSTPSTWNTPASMPAAWGHASLVNSPSYLTSTRSLSPMSGLFGSIWAPQSEVYETCCPISPATEHATHMENQVMCKEYYLGFNPFRAYMNLDIWTSTANRNANFPLSRDSSYCGNM", "length": 1597 }, "evidence": [ { "id": "HGNC:29146", "url": "https://alliancegenome.org/gene/HGNC:29146#orthology", "database": "AGR" }, { "id": "RGD:1583677", "url": "https://alliancegenome.org/gene/RGD:1583677#orthology", "database": "AGR" }, { "id": "MGI:2443399", "url": "https://alliancegenome.org/gene/MGI:2443399#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6110", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6110#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVD8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1039, "end_pos": 1041, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1098, "end_pos": 1100, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1240, "end_pos": 1242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1309, "end_pos": 1311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1332, "end_pos": 1334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1386, "end_pos": 1388, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1481, "end_pos": 1483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1485, "end_pos": 1487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1494, "end_pos": 1496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 430, "end_pos": 432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 575, "end_pos": 577, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 618, "end_pos": 620, "annotation": "n_glycosylation_sequon" }, { "start_pos": 673, "end_pos": 675, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 810, "end_pos": 812, "annotation": "n_glycosylation_sequon" }, { "start_pos": 880, "end_pos": 882, "annotation": "n_glycosylation_sequon" }, { "start_pos": 884, "end_pos": 886, "annotation": "n_glycosylation_sequon" }, { "start_pos": 900, "end_pos": 902, "annotation": "n_glycosylation_sequon" }, { "start_pos": 921, "end_pos": 923, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UVD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8" }, { "id": "PF24501", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24501" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TMEM131L fifth Ig-like", "eco_id": "ECO_0000259", "start_pos": 737, "end_pos": 801, "start_aa": "Asn", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UVD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8" }, { "id": "PF24499", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24499" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TMEM131L fourth Ig-like", "eco_id": "ECO_0000259", "start_pos": 561, "end_pos": 687, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UVD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8" }, { "id": "PF24498", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24498" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TMEM131L third Ig-like", "eco_id": "ECO_0000259", "start_pos": 388, "end_pos": 480, "start_aa": "Leu", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UVD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8" }, { "id": "PF12371", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12371" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein 131-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 87, "end_pos": 168, "start_aa": "Phe", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UVD8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVD8" }, { "id": "PF19532", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19532" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transmembrane protein 131-like second Ig-like", "eco_id": "ECO_0000259", "start_pos": 194, "end_pos": 344, "start_aa": "Lys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1039, "end_pos": 1041 }, { "start_pos": 1098, "end_pos": 1100 }, { "start_pos": 1240, "end_pos": 1242 }, { "start_pos": 1309, 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This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005171912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171912" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BGS5", "url": "https://www.uniprot.org/uniprotkb/A2BGS5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam219ab", "url": "https://www.uniprot.org/uniprotkb/A2BGS5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050522-213", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-213", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000013813", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000013813", "database": "Bgee", "categories": [ "Gene 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"MMEEIDRFQVPTEAEMQPFDPASSTTSEADSDTRESEPATLNYKPSPLHMKIDKQRELVRKGSLKNGNAGSPVNQQPKKNNVMARTRLVVPNKGYSSLDQSPDEKPLVALDTDSDDDFDMSRYSSSGYSSAEQINQDLNIQLLKDGYRLDEIPDDEDLDLIPPKSVNSTCMCCQATSSTACQIQ", "length": 184, "header": "tr|A2BGS5-1|A2BGS5_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=fam219ab PE=3 SV=1 CANONICAL=A2BGS5-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BJ47-1", "url": "https://www.uniprot.org/uniprotkb/A2BGS5/entry#A0A8M2BJ47-1", "sequence": { "sequence": "MMEEIDRFQVPTEAEMQPFDPASSTTSEADSDTRESEPATLNYKPSPLHMKIDKQRELVRKGSLKNGNAGSPVNQQPKKNNVMARTRLVVPNKGYSSLDQSPDEKPLVALDTDSDDDFDMSRYSSSGYSSAEINQDLNIQLLKDGYRLDEIPDDEDLDLIPPKSVNSTCMCCQATSSTACQIQ", "length": 183, "header": "tr|A0A8M2BJ47-1|A2BGS5_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=fam219ab PE=3 SV=1 CANONICAL=A2BGS5-1" }, "locus": {} }, { "isoform_ac": "A2BGS5-1", "url": "https://www.uniprot.org/uniprotkb/A2BGS5/entry#A2BGS5-1", "sequence": { 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"https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-213#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D772-1", "protein_name": "Protein FAM219A", "gene_name": "Fam219a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEEIDRFQDPAAASISDRDCDAREEKQRELARKGSLKNGSMGSPVNQQPKKNNVMARTRLVVPNKGYSSLDQSPDEKPLVALDTDSDDDFDMSRYSSSGYSSAEQINQDLNIQLLKDGYRLDEIPDDEDLDLIPPKSVNPTCMCCQATSSTACHIQ", "length": 157 }, "evidence": [ { "id": "RGD:1588668", "url": "https://alliancegenome.org/gene/RGD:1588668#orthology", "database": "AGR" }, { "id": "MGI:1919151", "url": "https://alliancegenome.org/gene/MGI:1919151#orthology", "database": "AGR" }, { "id": "HGNC:19920", "url": "https://alliancegenome.org/gene/HGNC:19920#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-213", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-213#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": 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"ac": "XP_021329698", "name": "neural proliferation differentiation and control protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329698" }, "gene_names": [ { "name": "npdc1b", "type": "recommended", "evidence": [ { "id": "A0A8M9PRN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRN9" } ] }, { "name": "npdc1b", "type": "synonym", "evidence": [ { "id": "XP_021329698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329698" } ] } ], "protein_names": [ { "name": "Neural proliferation differentiation and control protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PRN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRN9/entry#names_and_taxonomy" } ] }, { "name": "neural proliferation differentiation and control protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021329698", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329698" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021329698.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329698" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRN9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRN9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "npdc1b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRN9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-140106-58", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-58", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PRN9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PRN9", "database": "AlphaFoldDB", "categories": [] }, { "id": "556607", "url": "https://www.ncbi.nlm.nih.gov/gene/556607", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009635", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009635", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556607", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556607", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR23352", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23352", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23352:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23352:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06809", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06809", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021329698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329698", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BJ86", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BJ86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BJ86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BJ86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PRN9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PRN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-140106-58", "url": "https://zfin.org/ZDB-GENE-140106-58", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRSLSRPWASTLAEAFLITTVAVSAAMAVVGHCPRSLDCARERRHFCQPGSLHCGPCLDPFMENKRGKCVLRRRNHPAAKVSHLPELDEEIDILSSIISKHRESEMKHSAPSPAASKAPENKSGSSSHYKAPPTAATSIQPPTRGLISSTSPTSNTPFISAVHSAPFIIPYPSEDHSFIIFLGVFLMVGSVAMVLTGVCWVRMQRGCRLAQKVDYPAFGLIGPNSYDSGMSGDKKLAQSAQMYHFQLQKQQMMSLKQRSDSKIPDSGATSDEENEDGDFTVYECPGLAPTGEMEVKNPLFDDSTFHLHLQRSYN", "length": 314, "header": "tr|A0A8M9PRN9-1|A0A8M9PRN9_DANRE Isoform 1 of Neural proliferation differentiation and control protein 1 isoform X1 OS=Danio rerio OX=7955 GN=npdc1b PE=4 SV=2 CANONICAL=A0A8M9PRN9-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BJ86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRN9/entry#A0A8M2BJ86-1", "sequence": { "sequence": "MRSLSRPWASTLAEAFLITTVAVSAAMAVVGHCPRSLDCARERRHFCQPGSLHCGPCLDPFMENKRGKCVLRRRNHPAKVSHLPELDEEIDILSSIISKHRESEMKHSAPSPAASKAPENKSGSSSHYKAPPTAATSIQPPTRGLISSTSPTSNTPFISAVHSAPFIIPYPSEDHSFIIFLGVFLMVGSVAMVLTGVCWVRMQRGCRLAQKVDYPAFGLIGPNSYDSGMSGDKKLAQSAQMYHFQLQKQQMMSLKQRSDSKIPDSGATSDEENEDGDFTVYECPGLAPTGEMEVKNPLFDDSTFHLHLQRSYN", "length": 313, "header": "tr|A0A8M2BJ86-1|A0A8M9PRN9_DANRE Computationally mapped isoform of Neural proliferation differentiation and control protein 1 isoform X1 OS=Danio rerio OX=7955 GN=npdc1b PE=4 SV=2 CANONICAL=A0A8M9PRN9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PRN9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRN9/entry#A0A8M9PRN9-1", "sequence": { "sequence": "MRSLSRPWASTLAEAFLITTVAVSAAMAVVGHCPRSLDCARERRHFCQPGSLHCGPCLDPFMENKRGKCVLRRRNHPAAKVSHLPELDEEIDILSSIISKHRESEMKHSAPSPAASKAPENKSGSSSHYKAPPTAATSIQPPTRGLISSTSPTSNTPFISAVHSAPFIIPYPSEDHSFIIFLGVFLMVGSVAMVLTGVCWVRMQRGCRLAQKVDYPAFGLIGPNSYDSGMSGDKKLAQSAQMYHFQLQKQQMMSLKQRSDSKIPDSGATSDEENEDGDFTVYECPGLAPTGEMEVKNPLFDDSTFHLHLQRSYN", "length": 314, "header": "tr|A0A8M9PRN9-1|A0A8M9PRN9_DANRE Isoform 1 of Neural proliferation differentiation and control protein 1 isoform X1 OS=Danio rerio OX=7955 GN=npdc1b PE=4 SV=2 CANONICAL=A0A8M9PRN9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:556607", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556607", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O35795-1", "protein_name": "Ectonucleoside triphosphate diphosphohydrolase 2", "gene_name": "Entpd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGKLVSLVPPLLLAAAGLTGLLLLCVPTQDVREPPALKYGIVLDAGSSHTSMFVYKWPADKENDTGIVGQHSSCDVQGGGISSYANDPSKAGQSLVRCLEQALRDVPRDRHASTPLYLGATAGMRPFNLTSPEATARVLEAVTQTLTQYPFDFRGARILSGQDEGVFGWVTANYLLENFIKYGWVGRWIRPRKGTLGAMDLGGASTQITFETTSPSEDPGNEVHLRLYGQHYRVYTHSFLCYGRDQILLRLLASALQIHRFHPCWPKGYSTQVLLQEVYQSPCTMGQRPRAFNGSAIVSLSGTSNATLCRDLVSRLFNISSCPFSQCSFNGVFQPPVAGNFIAFSAFYYTVDFLTTVMGLPVGTLKQLEEATEITCNQTWTELQARVPGQKTRLADYCAVAMFIHQLLSRGYHFDERSFREVVFQKKAADTAVGWALGYMLNLTNLIPADLPGLRKGTHFSSWVALLLLFTVLILAALVLLLRQVRSAKSPGAL", "length": 495 }, "evidence": [ { "id": "HGNC:7899", "url": "https://alliancegenome.org/gene/HGNC:7899#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64322-1", "protein_name": "Neural proliferation differentiation and control protein 1", "gene_name": "Npdc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATPVPPPSPRHLRLLRLLLSGLILGAALNGATARRPDATTCPGSLDCALKRRAKCPPGAHACGPCLQSFQEDQRGFCVPRKHLSSGEGLPQPRLEEEIDSLAQELALKEKEAGHSRLTAQPLLEAAQKLLEPAATLGFSQWGQRLEPGLPSTHGTSSPIPHTSLSSRASSGPVQMSPLEPQGRHGNGLTLVLILAFCLASSAALAVAALCWCRLQREIRLTQKADYAATAKGPTSPSTPRISPGDQRLAHSAEMYHYQHQRQQMLCLERHKEPPKELESASSDEENEDGDFTVYECPGLAPTGEMEVRNPLFDHSTLSAPVPGPHSLPPLQ", "length": 332 }, "evidence": [ { "id": "HGNC:7899", "url": "https://alliancegenome.org/gene/HGNC:7899#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-58", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-58#orthology", "database": "AGR" }, { "id": "MGI:1099802", "url": "https://alliancegenome.org/gene/MGI:1099802#orthology", "database": "AGR" }, { "id": "FB:FBgn0265182", "url": "https://alliancegenome.org/gene/FB:FBgn0265182#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQX5-1", "protein_name": "Neural proliferation differentiation and control protein 1", "gene_name": "NPDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPLPPPSPRHLRLLRLLLSGLVLGAALRGAAAGHPDVAACPGSLDCALKRRARCPPGAHACGPCLQPFQEDQQGLCVPRMRRPPGGGRPQPRLEDEIDFLAQELARKESGHSTPPLPKDRQRLPEPATLGFSARGQGLELGLPSTPGTPTPTPHTSLGSPVSSDPVHMSPLEPRGGQGDGLALVLILAFCVAGAAALSVASLCWCRLQREIRLTQKADYATAKAPGSPAAPRISPGDQRLAQSAEMYHYQHQRQQMLCLERHKEPPKELDTASSDEENEDGDFTVYECPGLAPTGEMEVRNPLFDHAALSAPLPAPSSPPALP", "length": 325 }, "evidence": [ { "id": "HGNC:7899", "url": "https://alliancegenome.org/gene/HGNC:7899#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-58", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-58#orthology", "database": "AGR" }, { "id": "MGI:1099802", "url": "https://alliancegenome.org/gene/MGI:1099802#orthology", "database": "AGR" }, { "id": "FB:FBgn0265182", "url": "https://alliancegenome.org/gene/FB:FBgn0265182#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W0Z5-1", "protein_name": "Neural proliferation differentiation and control protein 1", "gene_name": "Atf-2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAARLEITVSLALAATLLCSILGHCEMSVYPGLRRRPIQPPVMDPQSEQEYAFLAQMMEQYARRRLQQQFDQQLHEINLKMDRQRQLLEQERYRQRQQELQVQREAEEDYESNGNNLNQQYDQYDNAEAEASYGSPMEAVSDLQSPPLYLPRLPNLPPLPSLPNRPSLGNSPNRNSVLRERIPFAVGPSDARFFDNPNDPSGELDSRALEDYEEYAPIEPTTEVATTASKTKIDTPVPAPVPVEPPKLLDAANTNFHRINPQSAAAAAVAGVNIPQSKEQPPHELNALINKLQKQSKAPSHLTLVNGGDSSQEQIVLRQHLGMNSEMGVYIVALIAGVSAAVTVGLLALGVTWFHNRHKAAADVEYPAYGVTGPNKDVSPSGDRKLAQSAQMYHYQHQKQQIIAMENQATDGSCGMSDVESDDDNEEGDYTVYECPGLAPTGEMEVKNPLFLDETPATPSNNLSSQTAGAANAAAATNNNITQATPQQPATLKKGTVKPNINLLNATGTAAAAASAASAASATGGEEPKQKRKSKK", "length": 536 }, "evidence": [ { "id": "HGNC:7899", "url": "https://alliancegenome.org/gene/HGNC:7899#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-58", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-58#orthology", "database": "AGR" }, { "id": "MGI:1099802", "url": "https://alliancegenome.org/gene/MGI:1099802#orthology", "database": "AGR" }, { "id": "FB:FBgn0265182", "url": "https://alliancegenome.org/gene/FB:FBgn0265182#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRN9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PM75-1", "uniprot_ac": "A0A8M9PM75", "uniprot_id": "A0A8M9PM75_DANRE", "mass": { "chemical_mass": 128700.0, "monoisotopic_mass": 128700.0 }, "refseq": { "ac": "XP_021323356", "name": "rho family-interacting cell polarization regulator 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323356" }, "gene_names": [ { "name": "ripor1", "type": "recommended", "evidence": [ { "id": "A0A8M9PM75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75" } ] }, { "name": "fam65a", "type": "synonym", "evidence": [ { "id": "XP_021323356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323356" }, { "id": "A0A8M9PM75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75" } ] }, { "name": "ripor1", "type": "synonym", "evidence": [ { "id": "XP_021323356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323356" } ] }, { "name": "si:dkey-45h7.2", "type": "synonym", "evidence": [ { "id": "XP_021323356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323356" }, { "id": "A0A8M9PM75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75" } ] } ], "protein_names": [ { "name": "Rho family-interacting cell polarization regulator 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PM75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75/entry#names_and_taxonomy" } ] }, { "name": "rho family-interacting cell polarization regulator 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323356", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323356" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323356" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PM75", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ripor1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050420-32", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050420-32", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PM75", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PM75", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000062178", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000062178", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "566573", "url": "https://www.ncbi.nlm.nih.gov/gene/566573", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031780", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031780", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566573", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566573", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M3AKD8", "url": "https://www.orthodb.org/?gene=A0A8M3AKD8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AUV4", "url": "https://www.orthodb.org/?gene=A0A8M3AUV4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PM75", "url": "https://www.orthodb.org/?gene=A0A8M9PM75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0AC58HU60", "url": "https://www.orthodb.org/?gene=A0AC58HU60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15829:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15829:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15903", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15903", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323356", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323356", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3AKD8", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AKD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AKD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AKD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AUV4", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AUV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AUV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AUV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P149", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P149", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P149-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P149-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PM75", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PM75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HTX4", "url": "https://www.uniprot.org/uniprotkb/A0AC58HTX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HTX4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HTX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HU60", "url": "https://www.uniprot.org/uniprotkb/A0AC58HU60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HU60-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HU60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050420-32", "url": "https://zfin.org/ZDB-GENE-050420-32", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MCHLHCLPGDTKEEGGPPAGSPSKSVSTMSLSVRPTRRVVGRSITRSQSFAGVNSYDKSYRSLSVFSTPGCVRKTPSRASRMFTLSTKSPPPKVPQPERLDEVYEALKRGLQSYLQVHQMELDGLNRQMKESKRNSRLGFLYELDKQVKVIERFMRRLEFHLSKIDELYEAYCMQRRLRDGADKMVKAYTASPGSREARESLSEANKSFKEYTENMCMLESELENQLGEFHIKMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEINGKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGSVSCETKDLFAALPQTVAVDINDLGTIKLSLEVTWNPFDKDDQSSSASTVNKAPTVNKRFSTYNQSPPDTPSLREQAFYTAPRSLMSKQRWSLLDVFRDTLTEKLTQSCSYSDVTSVRLGSALLTSHNMLRRQEDMENGTAWSNSSESSDDSSSPQLSLAMRHAHKNLVQPEVQAAPPAIEISFAPRESATSTPTRLANQKEEDEEEEEDEDLKKPAATIRVTTEAPAKPEVPNGHPRYSRSLSHISEISADGVLTERLAGESDEVTSTVSSVLDSDISMDVPHRAELCFVVPDTQESCSVPDPSTNEPSCPAEPMNCSECHSPAESVVRETAAEKASELTCGDKDSAHNALSQQMDNGDCRTDSSHEPQHTKTQTDNLLAEKSGSLVDSRSVGGLEGQSVDNGLEEALSGVLSSLDDYRGQFPELQVLEQELKMLEETLTTRSRSRSSSVSLTVETALESFDFLNTSDLEEEEEEEEEEDGEKQSVTDRSSTKERPAAVESAGEDEGCEARCWDTPSGPLSTNCPALDHTLLVHLKYCSSQLLRLGTFGPLRCGEMYALDRLLREARVLELIRWAVKDSRGADVQPEEVVPQLDQCQGAVLLWRQCTDGCGVYSSSAEAFLQALSDAYASRLPERGAGFTDAVFLRLLERILERKLPRRAGGTSKESLTLFQFWSYLEAEGVNDLDTHIPELAEEVWLVQCLQSGDQDVLIKCLKKPPECSLKREGLRAVSLLLRDPRGKVCSAASSLLRSLADQTRHRERALVSCLELLEDESIETRVCGCKALACLKAKESIEQLVYLCRTDKEDVRDAAKQALLVLGEEGKMAHRHLESSQDGMSRLFSPGSMASTAF", "length": 1158, "header": "tr|A0A8M9PM75-1|A0A8M9PM75_DANRE Isoform 1 of Rho family-interacting cell polarization regulator 1 isoform X1 OS=Danio rerio OX=7955 GN=ripor1 PE=1 SV=1 CANONICAL=A0A8M9PM75-1" }, "isoforms": [ { "isoform_ac": "A0A8M3AKD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75/entry#A0A8M3AKD8-1", "sequence": { "sequence": "MYSGYGGSPSKSVSTMSLSVRPTRRVVGRSITRSQSFAGVNSYDKSYRSLSVFSTPGCVRKTPSRASRMFTLSTKSPPPKVPQPERLDEVYEALKRGLQSYLQVHQMELDGLNRQMKESKRNSRLGFLYELDKQVKVIERFMRRLEFHLSKIDELYEAYCMQRRLRDGADKMVKAYTASPGSREARESLSEANKSFKEYTENMCMLESELENQLGEFHIKMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEINGKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGSVSCETKDLFAALPQTVAVDINDLGTIKLSLEVTWNPFDKDDQSSSASTVNKAPTVNKRFSTYNQSPPDTPSLREQAFYTAPRSLMSKQRWSLLDVFRDTLTEKLTQSCSYSDVTSVRLGSALLTSHNMLRRQEDMENGTAWSNSSESSDDSSSPQLSLAMRHAHKNLVQPEVQAAPPAIEISFAPRESATSTPTRLANQKEEDEEEEEDEDLKKPAATIRVTTEAPAKPEVPNGHPRYSRSLSHISEISADGVLTERLAGESDEVTSTVSSVLDSDISMDVPHRAELCFVVPDTQESCSVPDPSTNEPSCPAEPMNCSECHSPAESVVRETAAEKASELTCGDKDSAHNALSQQMDNGDCRTDSSHEPQHTKTQTDNLLAEKSGSLVDSRSVGGLEGQSVDNGLEEALSGVLSSLDDYRGQFPELQVLEQELKMLEETLTTRSRSRSSSVSLTVETALESFDFLNTSDLEEEEEEEEEEDGEKQSVTDRSSTKERPAAVESAGEDEGCEARCWDTPSGPLSTNCPALDHTLLVHLKYCSSQLLRLGTFGPLRCGEMYALDRLLREARVLELIRWAVKDSRGADVQPEEVVPQLDQCQGAVLLWRQCTDGCGVYSSSAEAFLQALSDAYASRLPERGAGFTDAVFLRLLERILERKLPRRAGGTSKESLTLFQFWSYLEAEGVNDLDTHIPELAEEVWLVQCLQSGDQDVLIKCLKKPPECSLKREGLRAVSLLLRDPRGKVCSAASSLLRSLADQTRHRERALVSCLELLEDESIETRVCGCKALACLKAKESIEQLVYLCRTDKEDVRDAAKQALLVLGEEGKMAHRHLESSQDGMSRLFSPGSMASTAF", "length": 1145, "header": "tr|A0A8M3AKD8-1|A0A8M9PM75_DANRE Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 isoform X1 OS=Danio rerio OX=7955 GN=ripor1 PE=1 SV=1 CANONICAL=A0A8M9PM75-1" }, "locus": {} }, { "isoform_ac": "A0A8M3AUV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75/entry#A0A8M3AUV4-1", "sequence": { "sequence": "MSLSVRPTRRVVGRSITRSQSFAGVNSYDKSYRSLSVFSTPGCVRKTPSRASRMFTLSTKSPPPKVPQPERLDEVYEALKRGLQSYLQVHQMELDGLNRQMKESKRNSRLGFLYELDKQVKVIERFMRRLEFHLSKIDELYEAYCMQRRLRDGADKMVKAYTASPGSREARESLSEANKSFKEYTENMCMLESELENQLGEFHIKMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEINGKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGSVSCETKDLFAALPQTVAVDINDLGTIKLSLEVTWNPFDKDDQSSSASTVNKAPTVNKRFSTYNQSPPDTPSLREQAFYTAPRSLMSKQRWSLLDVFRDTLTEKLTQSCSYSDVTSVRLGSALLTSHNMLRRQEDMENGTAWSNSSESSDDSSSPQLSLAMRHAHKNLVQPEVQAAPPAIEISFAPRESATSTPTRLANQKEEDEEEEEDEDLKKPAATIRVTTEAPAKPEVPNGHPRYSRSLSHISEISADGVLTERLAGESDEVTSTVSSVLDSDISMDVPHRAELCFVVPDTQESCSVPDPSTNEPSCPAEPMNCSECHSPAESVVRETAAEKASELTCGDKDSAHNALSQQMDNGDCRTDSSHEPQHTKTQTDNLLAEKSGSLVDSRSVGGLEGQSVDNGLEEALSGVLSSLDDYRGQFPELQVLEQELKMLEETLTTRSRSRSSSVSLTVETALESFDFLNTSDLEEEEEEEEEEDGEKQSVTDRSSTKERPAAVESAGEDEGCEARCWDTPSGPLSTNCPALDHTLLVHLKYCSSQLLRLGTFGPLRCGEMYALDRLLREARVLELIRWAVKDSRGADVQPEEVVPQLDQCQGAVLLWRQCTDGCGVYSSSAEAFLQALSDAYASRLPERGAGFTDAVFLRLLERILERKLPRRAGGTSKESLTLFQFWSYLEAEGVNDLDTHIPELAEEVWLVQCLQSGDQDVLIKCLKKPPECSLKREGLRAVSLLLRDPRGKVCSAASSLLRSLADQTRHRERALVSCLELLEDESIETRVCGCKALACLKAKESIEQLVYLCRTDKEDVRDAAKQALLVLGEEGKMAHRHLESSQDGMSRLFSPGSMASTAF", "length": 1130, "header": "tr|A0A8M3AUV4-1|A0A8M9PM75_DANRE Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 isoform X1 OS=Danio rerio OX=7955 GN=ripor1 PE=1 SV=1 CANONICAL=A0A8M9PM75-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P149-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75/entry#A0A8M9P149-1", "sequence": { "sequence": "MCHLHCLPGDTKEEGGPPAGSPSKSVSTMSLSVRPTRRVVGRSITRSQSFAGVNSYDKSYRSLSVFSTPGCVRKTPSRASRMFTLSTKSPPPKVPQPERLDEVYEALKRGLQSYLQVHQMELDGLNRQMKESKRNSRLGFLYELDKQVKVIERFMRRLEFHLSKIDELYEAYCMQRRLRDGADKMVKAYTASPGSREARESLSEANKSFKEYTENMCMLESELENQLGEFHIKMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEINGKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGSVSCETKDLFAALPQTVAVDINDLGTIKLSLEVTWNPFDKDDQSSSASTVNKAPTVNKRFSTYNQSPPDTPSLREQAFYNMLRRQEDMENGTAWSNSSESSDDSSSPQLSLAMRHAHKNLVQPEVQAAPPAIEISFAPRESATSTPTRLANQKEEDEEEEEDEDLKKPAATIRVTTEAPAKPEVPNGHPRYSRSLSHISEISADGVLTERLAGESDEVTSTVSSVLDSDISMDVPHRAELCFVVPDTQESCSVPDPSTNEPSCPAEPMNCSECHSPAESVVRETAAEKASELTCGDKDSAHNALSQQMDNGDCRTDSSHEPQHTKTQTDNLLAEKSGSLVDSRSVGGLEGQSVDNGLEEALSGVLSSLDDYRGQFPELQVLEQELKMLEETLTTRSRSRSSSVSLTVETALESFDFLNTSDLEEEEEEEEEEDGEKQSVTDRSSTKERPAAVESAGEDEGCEARCWDTPSGPLSTNCPALDHTLLVHLKYCSSQLLRLGTFGPLRCGEMYALDRLLREARVLELIRWAVKDSRGADVQPEEVVPQLDQCQGAVLLWRQCTDGCGVYSSSAEAFLQALSDAYASRLPERGAGFTDAVFLRLLERILERKLPRRAGGTSKESLTLFQFWSYLEAEGVNDLDTHIPELAEEVWLVQCLQSGDQDVLIKCLKKPPECSLKREGLRAVSLLLRDPRGKVCSAASSLLRSLADQTRHRERALVSCLELLEDESIETRVCGCKALACLKAKESIEQLVYLCRTDKEDVRDAAKQALLVLGEEGKMAHRHLESSQDGMSRLFSPGSMASTAF", "length": 1110, "header": "tr|A0A8M9P149-1|A0A8M9PM75_DANRE Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 isoform X1 OS=Danio rerio OX=7955 GN=ripor1 PE=1 SV=1 CANONICAL=A0A8M9PM75-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PM75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75/entry#A0A8M9PM75-1", "sequence": { "sequence": "MCHLHCLPGDTKEEGGPPAGSPSKSVSTMSLSVRPTRRVVGRSITRSQSFAGVNSYDKSYRSLSVFSTPGCVRKTPSRASRMFTLSTKSPPPKVPQPERLDEVYEALKRGLQSYLQVHQMELDGLNRQMKESKRNSRLGFLYELDKQVKVIERFMRRLEFHLSKIDELYEAYCMQRRLRDGADKMVKAYTASPGSREARESLSEANKSFKEYTENMCMLESELENQLGEFHIKMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEINGKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGSVSCETKDLFAALPQTVAVDINDLGTIKLSLEVTWNPFDKDDQSSSASTVNKAPTVNKRFSTYNQSPPDTPSLREQAFYTAPRSLMSKQRWSLLDVFRDTLTEKLTQSCSYSDVTSVRLGSALLTSHNMLRRQEDMENGTAWSNSSESSDDSSSPQLSLAMRHAHKNLVQPEVQAAPPAIEISFAPRESATSTPTRLANQKEEDEEEEEDEDLKKPAATIRVTTEAPAKPEVPNGHPRYSRSLSHISEISADGVLTERLAGESDEVTSTVSSVLDSDISMDVPHRAELCFVVPDTQESCSVPDPSTNEPSCPAEPMNCSECHSPAESVVRETAAEKASELTCGDKDSAHNALSQQMDNGDCRTDSSHEPQHTKTQTDNLLAEKSGSLVDSRSVGGLEGQSVDNGLEEALSGVLSSLDDYRGQFPELQVLEQELKMLEETLTTRSRSRSSSVSLTVETALESFDFLNTSDLEEEEEEEEEEDGEKQSVTDRSSTKERPAAVESAGEDEGCEARCWDTPSGPLSTNCPALDHTLLVHLKYCSSQLLRLGTFGPLRCGEMYALDRLLREARVLELIRWAVKDSRGADVQPEEVVPQLDQCQGAVLLWRQCTDGCGVYSSSAEAFLQALSDAYASRLPERGAGFTDAVFLRLLERILERKLPRRAGGTSKESLTLFQFWSYLEAEGVNDLDTHIPELAEEVWLVQCLQSGDQDVLIKCLKKPPECSLKREGLRAVSLLLRDPRGKVCSAASSLLRSLADQTRHRERALVSCLELLEDESIETRVCGCKALACLKAKESIEQLVYLCRTDKEDVRDAAKQALLVLGEEGKMAHRHLESSQDGMSRLFSPGSMASTAF", "length": 1158, "header": "tr|A0A8M9PM75-1|A0A8M9PM75_DANRE Isoform 1 of Rho family-interacting cell polarization regulator 1 isoform X1 OS=Danio rerio OX=7955 GN=ripor1 PE=1 SV=1 CANONICAL=A0A8M9PM75-1" }, "locus": {} }, { "isoform_ac": "A0AC58HTX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75/entry#A0AC58HTX4-1", "sequence": { "sequence": "MYSGYGGSPSKSVSTMSLSVRPTRRVVGRSITRSQSFAGVNSYDKSYRSLSVFSTPGCVRKTPSRASRMFTLSTKSPPPKVPQPERLDEVYEALKRGLQSYLQVHQMELDGLNRQMKESKRNSRLGFLYELDKQVKVIERFMRRLEFHLSKIDELYEAYCMQRRLRDGADKMVKAYTASPGSREARESLSEANKSFKEYTENMCMLESELENQLGEFHIKMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEINGKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGSVSCETKDLFAALPQTVAVDINDLGTIKLSLEVTWNPFDKDDQSSSASTVNKAPTVNKRFSTYNQSPPDTPSLREQAFYNMLRRQEDMENGTAWSNSSESSDDSSSPQLSLAMRHAHKNLVQPEVQAAPPAIEISFAPRESATSTPTRLANQKEEDEEEEEDEDLKKPAATIRVTTEAPAKPEVPNGHPRYSRSLSHISEISADGVLTERLAGESDEVTSTVSSVLDSDISMDVPHRAELCFVVPDTQESCSVPDPSTNEPSCPAEPMNCSECHSPAESVVRETAAEKASELTCGDKDSAHNALSQQMDNGDCRTDSSHEPQHTKTQTDNLLAEKSGSLVDSRSVGGLEGQSVDNGLEEALSGVLSSLDDYRGQFPELQVLEQELKMLEETLTTRSRSRSSSVSLTVETALESFDFLNTSDLEEEEEEEEEEDGEKQSVTDRSSTKERPAAVESAGEDEGCEARCWDTPSGPLSTNCPALDHTLLVHLKYCSSQLLRLGTFGPLRCGEMYALDRLLREARVLELIRWAVKDSRGADVQPEEVVPQLDQCQGAVLLWRQCTDGCGVYSSSAEAFLQALSDAYASRLPERGAGFTDAVFLRLLERILERKLPRRAGGTSKESLTLFQFWSYLEAEGVNDLDTHIPELAEEVWLVQCLQSGDQDVLIKCLKKPPECSLKREGLRAVSLLLRDPRGKVCSAASSLLRSLADQTRHRERALVSCLELLEDESIETRVCGCKALACLKAKESIEQLVYLCRTDKEDVRDAAKQALLVLGEEGKMAHRHLESSQDGMSRLFSPGSMASTAF", "length": 1097, "header": "tr|A0AC58HTX4-1|A0AC58HTX4_DANRE Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 isoform X5 OS=Danio rerio OX=7955 GN=ripor1 PE=1 SV=1 CANONICAL=A0A8M9PM75-1" }, "locus": {} }, { "isoform_ac": "A0AC58HU60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75/entry#A0AC58HU60-1", "sequence": { "sequence": "MSLSVRPTRRVVGRSITRSQSFAGVNSYDKSYRSLSVFSTPGCVRKTPSRASRMFTLSTKSPPPKVPQPERLDEVYEALKRGLQSYLQVHQMELDGLNRQMKESKRNSRLGFLYELDKQVKVIERFMRRLEFHLSKIDELYEAYCMQRRLRDGADKMVKAYTASPGSREARESLSEANKSFKEYTENMCMLESELENQLGEFHIKMKGLAGFARLCAGDQYEIFMKYGRQRWKLRGRIEINGKQVWDSEEMVFLPLITEFLSIKVTELKSLANHVVVGSVSCETKDLFAALPQTVAVDINDLGTIKLSLEVTWNPFDKDDQSSSASTVNKAPTVNKRFSTYNQSPPDTPSLREQAFYNMLRRQEDMENGTAWSNSSESSDDSSSPQLSLAMRHAHKNLVQPEVQAAPPAIEISFAPRESATSTPTRLANQKEEDEEEEEDEDLKKPAATIRVTTEAPAKPEVPNGHPRYSRSLSHISEISADGVLTERLAGESDEVTSTVSSVLDSDISMDVPHRAELCFVVPDTQESCSVPDPSTNEPSCPAEPMNCSECHSPAESVVRETAAEKASELTCGDKDSAHNALSQQMDNGDCRTDSSHEPQHTKTQTDNLLAEKSGSLVDSRSVGGLEGQSVDNGLEEALSGVLSSLDDYRGQFPELQVLEQELKMLEETLTTRSRSRSSSVSLTVETALESFDFLNTSDLEEEEEEEEEEDGEKQSVTDRSSTKERPAAVESAGEDEGCEARCWDTPSGPLSTNCPALDHTLLVHLKYCSSQLLRLGTFGPLRCGEMYALDRLLREARVLELIRWAVKDSRGADVQPEEVVPQLDQCQGAVLLWRQCTDGCGVYSSSAEAFLQALSDAYASRLPERGAGFTDAVFLRLLERILERKLPRRAGGTSKESLTLFQFWSYLEAEGVNDLDTHIPELAEEVWLVQCLQSGDQDVLIKCLKKPPECSLKREGLRAVSLLLRDPRGKVCSAASSLLRSLADQTRHRERALVSCLELLEDESIETRVCGCKALACLKAKESIEQLVYLCRTDKEDVRDAAKQALLVLGEEGKMAHRHLESSQDGMSRLFSPGSMASTAF", "length": 1082, "header": "tr|A0AC58HU60-1|A0AC58HU60_DANRE Computationally mapped isoform of Rho family-interacting cell polarization regulator 1 OS=Danio rerio OX=7955 GN=ripor1 PE=1 SV=1 CANONICAL=A0A8M9PM75-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Hematopoietic gene expression profile in zebrafish kidney marrow.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2004", "authors": "Song Huai-Dong, Sun Xiao-Jian, Deng Min, Zhang Guo-Wei, Zhou Yi, Wu Xin-Yan, Sheng Yan, Chen Yi, Ruan Zheng, Jiang Chun-Lei, Fan Hui-Yong, Zon Leonard I, Kanki John P, Liu Ting Xi, Look A Thomas, Chen Zhu", "evidence": [ { "database": "UniProtKB", "id": "A0AC58HU60", "url": "https://www.uniprot.org/uniprotkb/A0AC58HU60" } ], "reference": [ { "type": "PubMed", "id": "15520368", "url": "https://glygen.org/publication/PubMed/15520368" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0AC58HU60", "url": "https://www.uniprot.org/uniprotkb/A0AC58HU60" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:566573", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566573", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q4FZU8-1", "protein_name": "Rho family-interacting cell polarization regulator 1", "gene_name": "Ripor1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMSLSVRPQRRLLSARVSRSQSFAGVLGSQERGPRNFTVFSPPGPQRKPLVLSRVSRMFSVAHPAPKVPQPERLDLVYAALKRGLTAYLEVHQQEQEKLQRQIKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLENELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVIWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARYSSTPKPLVQQPEPLPVQVTFRRPESLSSGSMDEEPPLTPALVNGHAPYSRTLSHISEASVDAALTEAMEAVDLKCPAPGPSPLVYPESTHVEHVSSVPPVADNGRSATSPALSTAGPAPTFIDPASSTQLDLVHKATDSGSSELPSITHTMASSTYSAVSPINSVPGLTSTTVGSTHKPMPSPLTSTGSIPSVTDSIQTTTSPTHTTPSPTHTTVSPTHSTPSPTHTTVSPSNAALSPSNATPSLSHSTTSPTQKATMSTHTTSAVGPVQTTTSPISTTVSPSPSVDTAIISSSSAVPSVPGPEARPCSHPTSTPYTKADPTAACTSSPSLASSGPKPLTSPAPDSLEQILKSPSSSPSSIVPEPQRSELSLALVAQAPVPEATGGAGDRRLEEALRTLMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNDDEDEDNDSPGDRPTSSPEVVAEERLDSSNAQCLSTGCSALDATLVQHLYHCSCLLLKLGTFGPLRCQEAWALERLLREARVLQEVCEHSKLWGNAVTSAQEVVQFSASRPGFLTFWDQCTEGLNPFLCPVEQVLLTFCSQYGARLSLRQPGLAEAVCVKFLEDALGQKLPRRPHSGPGEQLTIFQFWSYVEVLDSPSMEAYVTETAEEVLLVQNLNSDDQAVVLKALRLAPEGRLRKDGLRALSSLLVHGNSKVMAAVSTQLRSLSLGPVFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRQLEESLDALPCLFGPSSMASTAF", "length": 1217 }, "evidence": [ { "id": "RGD:1307772", "url": "https://alliancegenome.org/gene/RGD:1307772#orthology", "database": "AGR" }, { "id": "MGI:1922937", "url": "https://alliancegenome.org/gene/MGI:1922937#orthology", "database": "AGR" }, { "id": "HGNC:25836", "url": "https://alliancegenome.org/gene/HGNC:25836#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050420-32", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050420-32#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FE6-1", "protein_name": "Rho family-interacting cell polarization regulator 1", "gene_name": "Ripor1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSLSVRPQRRLLSARVSRSQSFAGVLGSHERGPRSFTVFSPPGPPRKPLVLSRVSRMFSVAHPAPKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQRQIKESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYSTGSPGSREARDSLAEATRGHREYTESMCLLENELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIESSGKQVWDSEETVFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVIWSPFDKDDQPSAASTVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSTPKPLVQQPEPLPVQVAFRRPESLTSGSMDEEPAMTPSLVNGHAPYSRTLSHISEASVDAALTEAVEAVDSQSPIPGPSPLVYPDSTHVERVSSVLPVLNNGHSATSPALSTTGPAPTFIDPAPTTQLDLVHKTTDSAPSELPSITHTTTSSAYSAVSLVNSVPSLTSTTIGSAHTTTPSPLTSTGSVPNATDSTQATPSPTHSTPSPTHTTIRLTHTTVSPTHSSPSPIHTTPSPTHTTVSPTCTTPSSGHSTTSPTQEAKMSTHTTGAVGPVQTTTSPISTTESPSPSTDVAIISSSSAESTGPGTEPLPCSHPASPPYTKADPTASCTSYQSLASSGSKPLTSPAPDSPEQIPKSPSSSPSSSAPEPQHSEHNLAAVAQAPVPEATGGAGDRRLEEALGTLMSALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNDDEDEDNDGPGDRHTSSPEVVAEDRLDSSNGQSLSTGCSALDATLVQHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVFQEVCERSKLWGNSATSAQEVVQFSASRPGFLTFWDQCTEGLSPFICSVERVLLTFCSQYGARLSLRQPGLAEAVCVKFLEDALGQKLPRRPQPGPGEQFTIFQFWSYVEALDSPSMDAYVTETAEEVLLVQNLNSDDQAVVLKALRLAPEGRLRKDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPVFRERALLCFLDQLEDGDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRQLEESLDALPCIFGPSSMASTAF", "length": 1223 }, "evidence": [ { "id": "RGD:1307772", "url": "https://alliancegenome.org/gene/RGD:1307772#orthology", "database": "AGR" }, { "id": "MGI:1922937", "url": "https://alliancegenome.org/gene/MGI:1922937#orthology", "database": "AGR" }, { "id": "HGNC:25836", "url": "https://alliancegenome.org/gene/HGNC:25836#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050420-32", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050420-32#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZS17-1", "protein_name": "Rho family-interacting cell polarization regulator 1", "gene_name": "RIPOR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSLSVRPQRRLLSARVNRSQSFAGVLGSHERGPSLSFRSFPVFSPPGPPRKPPALSRVSRMFSVAHPAAKVPQPERLDLVYTALKRGLTAYLEVHQQEQEKLQGQIRESKRNSRLGFLYDLDKQVKSIERFLRRLEFHASKIDELYEAYCVQRRLRDGAYNMVRAYTTGSPGSREARDSLAEATRGHREYTESMCLLESELEAQLGEFHLRMKGLAGFARLCVGDQYEICMKYGRQRWKLRGRIEGSGKQVWDSEETIFLPLLTEFLSIKVTELKGLANHVVVGSVSCETKDLFAALPQVVAVDINDLGTIKLSLEVTWSPFDKDDQPSAASSVNKASTVTKRFSTYSQSPPDTPSLREQAFYNMLRRQEELENGTAWSLSSESSDDSSSPQLSGTARHSPAPRPLVQQPEPLPIQVAFRRPETPSSGPLDEEGAVAPVLANGHAPYSRTLSHISEASVDAALAEASVEAVGPESLAWGPSPPTHPAPTHGEHPSPVPPALDPGHSATSSTLGTTGSVPTSTDPAPSAHLDSVHKSTDSGPSELPGPTHTTTGSTYSAITTTHSAPSPLTHTTTGSTHKPIISTLTTTGPTLNIIGPVQTTTSPTHTMPSPTHTTASPTHTSTSPTHTPTSPTHKTSMSPPTTTSPTPSGMGLVQTATSPTHPTTSPTHPTTSPILINVSPSTSLELATLSSPSKHSDPTLPGTDSLPCSPPVSNSYTQADPMAPRTPHPSPAHSSRKPLTSPAPDPSESTVQSLSPTPSPPTPAPQHSDLCLAMAVQTPVPTAAGGSGDRSLEEALGALMAALDDYRGQFPELQGLEQEVTRLESLLMQRQGLTRSRASSLSITVEHALESFSFLNEDEDEDNDVPGDRPPSSPEAGAEDSIDSPSARPLSTGCPALDAALVRHLYHCSRLLLKLGTFGPLRCQEAWALERLLREARVLEAVCEFSRRWEIPASSAQEVVQFSASRPGFLTFWDQCTERLSCFLCPVERVLLTFCNQYGARLSLRQPGLAEAVCVKFLEDALGQKLPRRPQPGPGEQLTVFQFWSFVETLDSPTMEAYVTETAEEVLLVRNLNSDDQAVVLKALRLAPEGRLRRDGLRALSSLLVHGNNKVMAAVSTQLRSLSLGPTFRERALLCFLDQLEDEDVQTRVAGCLALGCIKAPEGIEPLVYLCQTDTEAVREAARQSLQQCGEEGQSAHRRLEESLDALPRIFGPGSMASTAF", "length": 1223 }, "evidence": [ { "id": "RGD:1307772", "url": "https://alliancegenome.org/gene/RGD:1307772#orthology", "database": "AGR" }, { "id": "MGI:1922937", "url": "https://alliancegenome.org/gene/MGI:1922937#orthology", "database": "AGR" }, { "id": "HGNC:25836", "url": "https://alliancegenome.org/gene/HGNC:25836#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050420-32", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050420-32#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 444, "end_pos": 446, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 623, "end_pos": 625, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PM75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM75" }, { "id": "PF15903", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15903" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM65 N-terminal", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 387, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 444, "end_pos": 446 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 623, "end_pos": 625 }, { "start_pos": 772, "end_pos": 774 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PNN1-1", "uniprot_ac": "A0A8M9PNN1", "uniprot_id": "A0A8M9PNN1_DANRE", "mass": { "chemical_mass": 158296.0, "monoisotopic_mass": 158296.0 }, "refseq": { "ac": "XP_021323851", "name": "collagen alpha-1(XVI) chain isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323851" }, "gene_names": [ { "name": "si:dkey-27a13.3", "type": "recommended", "evidence": [ { "id": "A0A8M9PNN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1" } ] }, { "name": "col16a1", "type": "synonym", "evidence": [ { "id": "XP_021323851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323851" }, { "id": "A0A8M9PNN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1" } ] } ], "protein_names": [ { "name": "Collagen alpha-1(XVI) chain", "type": "recommended", "evidence": [ { "id": "A0A8M9PNN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1/entry#names_and_taxonomy" } ] }, { "name": "collagen alpha-1(XVI) chain isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323851", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323851" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323851" } ] }, { "annotation": "Involved in mediating cell attachment and inducing integrin-mediated cellular reactions, such as cell spreading and alterations in cell morphology.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9P210", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P210#function" }, { "database": "UniProtKB", "id": "ARBA00057339", "url": "https://www.uniprot.org/uniprotkb/ARBA00057339#function" }, { "database": "UniProtKB", "id": "A0A8M9PB75", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB75#function" }, { "database": "UniProtKB", "id": "A0A8M9PNN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1#function" }, { "database": "UniProtKB", "id": "A0A8M3AL30", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AL30#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-27a13.3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-446", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-446", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PNN1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PNN1", "database": "AlphaFoldDB", "categories": [] }, { "id": "100535782", "url": "https://www.ncbi.nlm.nih.gov/gene/100535782", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048287", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048287", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100535782", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100535782", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M3AL30", "url": "https://www.orthodb.org/?gene=A0A8M3AL30", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PNN1", "url": "https://www.orthodb.org/?gene=A0A8M9PNN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF1082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF1082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24023:SF372", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24023:SF372", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01391", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01391", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323851", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323851", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3AL30", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AL30", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AL30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AL30-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P210", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P210", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P210-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P210-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PB75", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PB75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PB75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PNN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PNN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-446", "url": "https://zfin.org/ZDB-GENE-060503-446", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRVVCSSLVLLTICLGHWGQLASAEGEGLVSKSKDEFVKGVICPSIQVEDWKFPQTARHNITGFNLARRFSLLMNSEVKKIRNPRGPVILRLGKVQLIQPTNQVFPHGLPEEFTLVFTLLLKKKSLNESIYLFQISDEHGYPQFSLDWNGPDGNLALRARGADPEGPMVGCVFDGDGVESLMDKRWHKVALSLQRESASLHVDCSSIENKPLELRGQLPISGHTLLGMRATDAAPVEIDIQQVMVYCDPSLAIQEACCEIPGARCPPDAPKSRRAAENQVEFVPNPFSQAILGSKELAEKCAGCVLLSEESSVIQEGQSGLKGEKGDRGLDCTGAGVPGRCLEGAKGEKGEKGESGLAANWGEAVGVKGVKGQKGEVGAPGLAGSPGRDGRANPICVVGPKGQKGAPGVVGPEGLAGEPGQPGFPGLPGVGKPGLPGPPGGSSGSKGEKGDSGTPGEDGKPGEPGPRGPWGPKGEKGEPCEPCQVISSESGNTLGSQSKQGAKGEPGVPGKSEQGPPGLPGVDGRTGEKGEAGVDGAKGEKGEPCSGCPSNGLNPAGILKQTQKGEKGDPGVGQKGEQGEPGQIGFGGLKGEKGNAGSRGNEGKTGKPGPRGPSGKDGNKGAKGDTGLPGIGTPGLKGEKGDSCGACQSSPSEVGSGPPTIKLTGERGPPGPAGPPGEGAEGKQGPPGLQGFKGEKGDQGLQGDSGTPGTPGVAGPQGEPGRNGLNGLKGEKGDACDSCPSLPEGNGDVVGLPGPKGERGEPGLPGEGREGKQGRPGPPGVQGPPGLKGSQGDSGPAGIGLPGPQGEQGPRGFPGAAGPEGRSGLIGPMGPSGLRGPKGEIGPPGPQGPMVTGPVGPPGRDGTAGFPGIPGQDGAPGVKGPKGDKGEPGECNCLHNMFPGTGGPGVPGGENRVQPGPQGPPGPPGPPGPPGPQGFTGIPGPQGIPGNDGLPGKAGPPGQANLLPQDSASPGKEGCGDCSKGLPGVPGTVGAKGEKGDQGKPGVVPLEGCERCFELQREETPSGPTGNSGPCVGTPGAPGFPGQPGVKGEPGPRGERGPPGTPGNPGNIGFPGPQGPPGLSGQQGQRGTDGNPGLKGEQGPPGSPGYPGTMGPPGLPGLKGERGSPGTVGLKGESGPPGSPGYQGPVGPAGPKGEAGASGPGGAKGDQGFQGSPGFPGQQGPPGFPGKAGPPGPPGPQAEKGVAGVAGPQGPTGPPGSPGSPGMPGPPGMEGLDGKDGKPGLRGEPGPAGQPGLRGIPGFKGIKGHTGLPGMKGERGPQGPAGASGRPGLEGDLGPPGPQGPPGAPGHLGAVGPVGPPGPVGPPGAGTKGDKGEPGERGQGGLPGPPGLPGHPGLMGEPGSDGSAGKDGAPGLPGEPGPQGVKGDAGAEGQRGPPGERGRPGPPGGGLGFGSKGPEGIIGPAGPRGERGSPGSPGQAGAPGLPGIPGNDAVVNYDELRSFIRQQVIKIFDERMGYYMSRMQMPVEMVASPGRPGPPGKDGNPGLPGPAGMPGRPGQIGREGRQGPMGPPGGPGVKGEKGDKGVGEMGDSGPPGAPGLPGPPGYGKMGPPGPSGQQGVPGIPGPPGPSGQKGKDGRCHPSDCMSMPMEYNPKGPPPKGPMY", "length": 1619, "header": "tr|A0A8M9PNN1-1|A0A8M9PNN1_DANRE Isoform 1 of Collagen alpha-1(XVI) chain OS=Danio rerio OX=7955 GN=si:dkey-27a13.3 PE=3 SV=1 CANONICAL=A0A8M9PNN1-1" }, "isoforms": [ { "isoform_ac": "A0A8M3AL30-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1/entry#A0A8M3AL30-1", "sequence": { "sequence": "MRVVCSSLVLLTICLGHWGQLASAEGVICPSIQVEDWKFPQTARHNITGFNLARRFSLLMNSEVKKIRNPRGPVILRLGKVQLIQPTNQVFPHGLPEEFTLVFTLLLKKKSLNESIYLFQISDEHGYPQFSLDWNGPDGNLALRARGADPEGPMVGCVFDGDGVESLMDKRWHKVALSLQRESASLHVDCSSIENKPLELRGQLPISGHTLLGMRATDAAPVEIDIQQVMVYCDPSLAIQEACCEIPGARCPPDAPKSRRAAENQVEFVPNPFSQAILGSKELAEKCAGCVLLSEESSVIQEGQSGLKGEKGDRGLDCTGAGVPGRCLEGAKGEKGEKGESGLAANWGEAVGVKGVKGQKGEVGAPGLAGSPGRDGRANPICVVGPKGQKGAPGVVGPEGLAGEPGQPGFPGLPGVGKPGLPGPPGGSSGSKGEKGDSGTPGEDGKPGEPGPRGPWGPKGEKGEPCEPCQVISSESGNTLGSQSKQGAKGEPGVPGKSEQGPPGLPGVDGRTGEKGEAGVDGAKGEKGEPCSGCPSNGLNPAGILKQTQKGEKGDPGVGQKGEQGEPGQIGFGGLKGEKGNAGSRGNEGKTGKPGPRGPSGKDGNKGAKGDTGLPGIGTPGLKGEKGDSCGACQSSPSEVGSGPPTIKLTGERGPPGPAGPPGEGAEGKQGPPGLQGFKGEKGDQGLQGDSGTPGTPGVAGPQGEPGRNGLNGLKGEKGDACDSCPSLPEGNGDVVGLPGPKGERGEPGLPGEGREGKQGRPGPPGVQGPPGLKGSQGDSGPAGIGLPGPQGEQGPRGFPGAAGPEGRSGLIGPMGPSGLRGPKGEIGPPGPQGPMVTGPVGPPGRDGTAGFPGIPGQDGAPGVKGPKGDKGEPGECNCLHNMFPGTGGPGVPGGENRVQPGPQGPPGPPGPPGPPGPQGFTGIPGPQGIPGNDGLPGKAGPPGQANLLPQDSASPGKEGCGDCSKGLPGVPGTVGAKGEKGDQGKPGVVPLEGCERCFELQREETPSGPTGNSGPCVGTPGAPGFPGQPGVKGEPGPRGERGPPGTPGNPGNIGFPGPQGPPGLSGQQGQRGTDGNPGLKGEQGPPGSPGYPGTMGPPGLPGLKGERGSPGTVGLKGESGPPGSPGYQGPVGPAGPKGEAGASGPGGAKGDQGFQGSPGFPGQQGPPGFPGKAGPPGPPGPQAEKGVAGVAGPQGPTGPPGSPGSPGMPGPPGMEGLDGKDGKPGLRGEPGPAGQPGLRGIPGFKGIKGHTGLPGMKGERGPQGPAGASGRPGLEGDLGPPGPQGPPGAPGHLGAVGPVGPPGPVGPPGAGTKGDKGEPGERGQGGLPGPPGLPGHPGLMGEPGSDGSAGKDGAPGLPGEPGPQGVKGDAGAEGQRGPPGERGRPGPPGGGLGFGSKGPEGIIGPAGPRGERGSPGSPGQAGAPGLPGIPGNDAVVNYDELRSFIRQQVIKIFDERMGYYMSRMQMPVEMVASPGRPGPPGKDGNPGLPGPAGMPGRPGQIGREGRQGPMGPPGGPGVKGEKGDKGVGEMGDSGPPGAPGLPGPPGYGKMGPPGPSGQQGVPGIPGPPGPSGQKGKDGRCHPSDCMSMPMEYNPKGPPPKGPMY", "length": 1605, "header": "tr|A0A8M3AL30-1|A0A8M9PNN1_DANRE Computationally mapped isoform of Collagen alpha-1(XVI) chain OS=Danio rerio OX=7955 GN=si:dkey-27a13.3 PE=3 SV=1 CANONICAL=A0A8M9PNN1-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P210-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1/entry#A0A8M9P210-1", "sequence": { "sequence": "MRVVCSSLVLLTICLGHWGQLASAEGEGLVSKSKDEFVKGVICPSIQVEDWKFPQTARHNITGFNLARRFSLLMNSEVKKIRNPRGPVILRLGKVQLIQPTNQVFPHGLPEEFTLVFTLLLKKKSLNESIYLFQISDEHGYPQFSLDWNGPDGNLALRARGADPEGPMVGCVFDGDGVESLMDKRWHKVALSLQRESASLHVDCSSIENKPLELRGQLPISGHTLLGMRATDAAPVEIDIQQVMVYCDPSLAIQEACCEIPGARCPPDAPKSRRAAENQVEFVPNPFSQAILGSKELAEKVIQEGQSGLKGEKGDRGLDCTGAGVPGRCLEGAKGEKGEKGESGLAANWGEAVGVKGVKGQKGEVGAPGLAGSPGRDGRANPICVVGPKGQKGAPGVVGPEGLAGEPGQPGFPGLPGVGKPGLPGPPGGSSGSKGEKGDSGTPGEDGKPGEPGPRGPWGPKGEKGEPCEPCQVISSESGNTLGSQSKQGAKGEPGVPGKSEQGPPGLPGVDGRTGEKGEAGVDGAKGEKGEPCSGCPSNGLNPAGILKQTQKGEKGDPGVGQKGEQGEPGQIGFGGLKGEKGNAGSRGNEGKTGKPGPRGPSGKDGNKGAKGDTGLPGIGTPGLKGEKGDSCGACQSSPSEVGSGPPTIKLTGERGPPGPAGPPGEGAEGKQGPPGLQGFKGEKGDQGLQGDSGTPGTPGVAGPQGEPGRNGLNGLKGEKGDACDSCPSLPEGNGDVVGLPGPKGERGEPGLPGEGREGKQGRPGPPGVQGPPGLKGSQGDSGPAGIGLPGPQGEQGPRGFPGAAGPEGRSGLIGPMGPSGLRGPKGEIGPPGPQGPMVTGPVGPPGRDGTAGFPGIPGQDGAPGVKGPKGDKGEPGECNCLHNMFPGTGGPGVPGGENRVQPGPQGPPGPPGPPGPPGPQGFTGIPGPQGIPGNDGLPGKAGPPGQANLLPQDSASPGKEGCGDCSKGLPGVPGTVGAKGEKGDQGKPGVVPLEGCERCFELQREETPSGPTGNSGPCVGTPGAPGFPGQPGVKGEPGPRGERGPPGTPGNPGNIGFPGPQGPPGLSGQQGQRGTDGNPGLKGEQGPPGSPGYPGTMGPPGLPGLKGERGSPGTVGLKGESGPPGSPGYQGPVGPAGPKGEAGASGPGGAKGDQGFQGSPGFPGQQGPPGFPGKAGPPGPPGPQAEKGVAGVAGPQGPTGPPGSPGSPGMPGPPGMEGLDGKDGKPGLRGEPGPAGQPGLRGIPGFKGIKGHTGLPGMKGERGPQGPAGASGRPGLEGDLGPPGPQGPPGAPGHLGAVGPVGPPGPVGPPGAGTKGDKGEPGERGQGGLPGPPGLPGHPGLMGEPGSDGSAGKDGAPGLPGEPGPQGVKGDAGAEGQRGPPGERGRPGPPGGGLGFGSKGPEGIIGPAGPRGERGSPGSPGQAGAPGLPGIPGNDAVVNYDELRSFIRQQVIKIFDERMGYYMSRMQMPVEMVASPGRPGPPGKDGNPGLPGPAGMPGRPGQIGREGRQGPMGPPGGPGVKGEKGDKGVGEMGDSGPPGAPGLPGPPGYGKMGPPGPSGQQGVPGIPGPPGPSGQKGKDGRCHPSDCMSMPMEYNPKGPPPKGPMY", "length": 1607, "header": "tr|A0A8M9P210-1|A0A8M9PNN1_DANRE Computationally mapped isoform of Collagen alpha-1(XVI) chain OS=Danio rerio OX=7955 GN=si:dkey-27a13.3 PE=3 SV=1 CANONICAL=A0A8M9PNN1-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PB75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1/entry#A0A8M9PB75-1", "sequence": { "sequence": "MRVVCSSLVLLTICLGHWGQLASAEGEGLVSKSKDEFVKGVICPSIQVEDWKFPQTARHNITGFNLARRFSLLMNSEVKKIRNPRGPVILRLGKVQLIQPTNQVFPHGLPEEFTLVFTLLLKKKSLNESIYLFQISDEHGYPQFSLDWNGPDGNLALRARGADPEGPMVGCVFDGDGVESLMDKRWHKVALSLQRESASLHVDCSSIENKPLELRGQLPISGHTLLGMRATDAAPVEIDIQQVMVYCDPSLAIQEACCEIPGARCPPDAPKSRRAAENQVEFVPNPFSQAILGSKELAEKCAGCVLLSEESSVIQEGQSGLKGEKGDRGLDCTGAGVPGRCLEGAKGEKGEKGESGLAANWGEAVGVKGVKGQKGEVGAPGLAGSPGRDGRANPICVVGPKGQKGAPGVVGPEGLAGEPGQPGFPGLPGVGKPGLPGPPGGSSGSKGEKGDSGTPGEDGKPGEPGPRGPWGPKGEKGEPCEPCQVISSESGNTLGSQSKQGAKGEPGVPGKSEQGPPGLPGVDGRTGEKGEAGVDGAKGEKGEPCSGCPSNGLNPAGILKQTQKGEKGDPGVGQKGEQGEPGQIGFGGLKGEKGNAGSRGNEGKTGKPGPRGPSGKDGNKGAKGDTGLPGIGTPGLKGEKGDSCGACQSSPSEVGSGPPTIKLTGERGPPGPAGPPGEGAEGKQGPPGLQGFKGEKGDQGLQGDSGTPGTPGVAGPQGEPGRNGLNGLKGEKGDACDSCPSLPEGNGDVVGLPGPKGERGEPGLPGEGREGKQGRPGPPGVQGPPGLKGSQGDSGPAGIGLPGPQGEQGPRGFPGAAGPEGRSGLIGPMGPSGLRGPKGEIGPPGPQGPMVTGPVGPPGRDGTAGFPGIPGQDGAPGVKGPKGDKGEPGECNCLHNMFPGTGGPGVPGGENRVQPGPQGPPGPPGPPGPPGPQGFTGIPGPQNLLPQDSASPGKEGCGDCSKGLPGVPGTVGAKGEKGDQGKPGVVPLEGCERCFELQREETPSGPTGNSGPCVGTPGAPGFPGQPGVKGEPGPRGERGPPGTPGNPGNIGFPGPQGPPGLSGQQGQRGTDGNPGLKGEQGPPGSPGYPGTMGPPGLPGLKGERGSPGTVGLKGESGPPGSPGYQGPVGPAGPKGEAGASGPGGAKGDQGFQGSPGFPGQQGPPGFPGKAGPPGPPGPQAEKGVAGVAGPQGPTGPPGSPGSPGMPGPPGMEGLDGKDGKPGLRGEPGPAGQPGLRGIPGFKGIKGHTGLPGMKGERGPQGPAGASGRPGLEGDLGPPGPQGPPGAPGHLGAVGPVGPPGPVGPPGAGTKGDKGEPGERGQGGLPGPPGLPGHPGLMGEPGSDGSAGKDGAPGLPGEPGPQGVKGDAGAEGQRGPPGERGRPGPPGGGLGFGSKGPEGIIGPAGPRGERGSPGSPGQAGAPGLPGIPGNDAVVNYDELRSFIRQQVIKIFDERMGYYMSRMQMPVEMVASPGRPGPPGKDGNPGLPGPAGMPGRPGQIGREGRQGPMGPPGGPGVKGEKGDKGVGEMGDSGPPGAPGLPGPPGYGKMGPPGPSGQQGVPGIPGPPGPSGQKGKDGRCHPSDCMSMPMEYNPKGPPPKGPMY", "length": 1601, "header": "tr|A0A8M9PB75-1|A0A8M9PNN1_DANRE Computationally mapped isoform of Collagen alpha-1(XVI) chain OS=Danio rerio OX=7955 GN=si:dkey-27a13.3 PE=3 SV=1 CANONICAL=A0A8M9PNN1-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PNN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1/entry#A0A8M9PNN1-1", "sequence": { "sequence": "MRVVCSSLVLLTICLGHWGQLASAEGEGLVSKSKDEFVKGVICPSIQVEDWKFPQTARHNITGFNLARRFSLLMNSEVKKIRNPRGPVILRLGKVQLIQPTNQVFPHGLPEEFTLVFTLLLKKKSLNESIYLFQISDEHGYPQFSLDWNGPDGNLALRARGADPEGPMVGCVFDGDGVESLMDKRWHKVALSLQRESASLHVDCSSIENKPLELRGQLPISGHTLLGMRATDAAPVEIDIQQVMVYCDPSLAIQEACCEIPGARCPPDAPKSRRAAENQVEFVPNPFSQAILGSKELAEKCAGCVLLSEESSVIQEGQSGLKGEKGDRGLDCTGAGVPGRCLEGAKGEKGEKGESGLAANWGEAVGVKGVKGQKGEVGAPGLAGSPGRDGRANPICVVGPKGQKGAPGVVGPEGLAGEPGQPGFPGLPGVGKPGLPGPPGGSSGSKGEKGDSGTPGEDGKPGEPGPRGPWGPKGEKGEPCEPCQVISSESGNTLGSQSKQGAKGEPGVPGKSEQGPPGLPGVDGRTGEKGEAGVDGAKGEKGEPCSGCPSNGLNPAGILKQTQKGEKGDPGVGQKGEQGEPGQIGFGGLKGEKGNAGSRGNEGKTGKPGPRGPSGKDGNKGAKGDTGLPGIGTPGLKGEKGDSCGACQSSPSEVGSGPPTIKLTGERGPPGPAGPPGEGAEGKQGPPGLQGFKGEKGDQGLQGDSGTPGTPGVAGPQGEPGRNGLNGLKGEKGDACDSCPSLPEGNGDVVGLPGPKGERGEPGLPGEGREGKQGRPGPPGVQGPPGLKGSQGDSGPAGIGLPGPQGEQGPRGFPGAAGPEGRSGLIGPMGPSGLRGPKGEIGPPGPQGPMVTGPVGPPGRDGTAGFPGIPGQDGAPGVKGPKGDKGEPGECNCLHNMFPGTGGPGVPGGENRVQPGPQGPPGPPGPPGPPGPQGFTGIPGPQGIPGNDGLPGKAGPPGQANLLPQDSASPGKEGCGDCSKGLPGVPGTVGAKGEKGDQGKPGVVPLEGCERCFELQREETPSGPTGNSGPCVGTPGAPGFPGQPGVKGEPGPRGERGPPGTPGNPGNIGFPGPQGPPGLSGQQGQRGTDGNPGLKGEQGPPGSPGYPGTMGPPGLPGLKGERGSPGTVGLKGESGPPGSPGYQGPVGPAGPKGEAGASGPGGAKGDQGFQGSPGFPGQQGPPGFPGKAGPPGPPGPQAEKGVAGVAGPQGPTGPPGSPGSPGMPGPPGMEGLDGKDGKPGLRGEPGPAGQPGLRGIPGFKGIKGHTGLPGMKGERGPQGPAGASGRPGLEGDLGPPGPQGPPGAPGHLGAVGPVGPPGPVGPPGAGTKGDKGEPGERGQGGLPGPPGLPGHPGLMGEPGSDGSAGKDGAPGLPGEPGPQGVKGDAGAEGQRGPPGERGRPGPPGGGLGFGSKGPEGIIGPAGPRGERGSPGSPGQAGAPGLPGIPGNDAVVNYDELRSFIRQQVIKIFDERMGYYMSRMQMPVEMVASPGRPGPPGKDGNPGLPGPAGMPGRPGQIGREGRQGPMGPPGGPGVKGEKGDKGVGEMGDSGPPGAPGLPGPPGYGKMGPPGPSGQQGVPGIPGPPGPSGQKGKDGRCHPSDCMSMPMEYNPKGPPPKGPMY", "length": 1619, "header": "tr|A0A8M9PNN1-1|A0A8M9PNN1_DANRE Isoform 1 of Collagen alpha-1(XVI) chain OS=Danio rerio OX=7955 GN=si:dkey-27a13.3 PE=3 SV=1 CANONICAL=A0A8M9PNN1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1061, "start_aa": "Thr", "end_pos": 1061, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1061", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1212, "start_aa": "Thr", "end_pos": 1212, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1212", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 454, "start_aa": "Thr", "end_pos": 454, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr454", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 707, "start_aa": "Thr", "end_pos": 707, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr707", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 710, "start_aa": "Thr", "end_pos": 710, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr710", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100535782", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100535782", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1" } ], "pmid": "" }, { "name": "extracellular matrix organization", "id": "GO:0030198", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030198", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "basement membrane", "id": "GO:0005604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005604", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "extracellular matrix structural constituent conferring tensile strength", "id": "GO:0030020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PNN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNN1" }, { "id": "SM00210", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00210" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thrombospondin-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 63, "end_pos": 249, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 454, 707, 710, 1061, 1212 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 60, "end_pos": 62 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 5 }, { "field": "total_sites", "count": 5 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 5 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 5 }, { "field": "exact_o_linked_sites", "count": 5 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UTF1-1", "uniprot_ac": "A0A8N7UTF1", "uniprot_id": "A0A8N7UTF1_DANRE", "mass": { "chemical_mass": 165974.0, "monoisotopic_mass": 165974.0 }, "refseq": { "ac": "XP_697512", "name": "CD109 antigen isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697512" }, "gene_names": [ { "name": "cd109", "type": "recommended", "evidence": [ { "id": "A0A8N7UTF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTF1" } ] }, { "name": "cd109", "type": "synonym", "evidence": [ { "id": "XP_697512", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697512" } ] } ], "protein_names": [ { "name": "CD109 antigen isoform X1", "type": "synonym", "evidence": [ { "id": "XP_697512", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697512" }, { "id": "A0A8N7UTF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTF1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_697512.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_697512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697512" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UTF1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTF1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cd109", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTF1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120215-253", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-253", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UTF1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UTF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd02897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "569058", "url": "https://www.ncbi.nlm.nih.gov/gene/569058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569058", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569058", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M3ATH0", "url": "https://www.orthodb.org/?gene=A0A8M3ATH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UTF1", "url": "https://www.orthodb.org/?gene=A0A8N7UTF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412:SF136", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412:SF136", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07678", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07678", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_697512", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697512", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3ATH0", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ATH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3ATH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ATH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UTF1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UTF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120215-253", "url": "https://zfin.org/ZDB-GENE-120215-253", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEWLQFFGILVCSLVCRGAMVTSSARQNLSYLISVSEVLRCGVPTTLSVTVLSDYPINVTARLTHGKTSVAQTQSTVPAGSSRLLSLPPVFYDDMTYWYPYQLNVEGFSGTHLVFSNSTSMVFSPRCMSIFIQTDKNYYQPGQTVKFRVVSVTPDGKPYSGRTDIFIRDPRGNMIRQWLAVDSFLGVISKELNISQNPPLGSWKITAGVNDVIHERAFTVDYYVLPRFEVKLDVPSVLYCEDTLMGTVTAKYFYGKPVSGFMDVRFVHGFNGIEMRYDHTEMIEGSAEITFDMKDFSTRFNDYSYSYYDGYRPIEFIDVNVNITESATGLMYNSSARVSIVTEKYKLEFLQYPHIVKPSMTFTAKLKLSLYDQRPLSAEDQIESVYLAVTQHKLSPWTWMWSDGGPLGPRMMNNTPSTSFPPNSDGGPLGPHMMNSTPPTSFTPIYDLPVQNIELPVTADGLMSFQIHLSDSVATLDLEARFKDTVQHLQLYRSYSSPSKSYIQLHRDSEPQVGRSLNFTLESSFNLTKIHYLVTSRAGVVDAGTVQSSSFSLNTDHLWAPQACVMVYYTLPDGEIVNDALHVSFTKVLRNTVSVRWSQDRAEPAESVSLSVSVSEPGSVLGILVVDKATLNSAEDNGLSEKTVLEEFLSYSREMTHTDNRGMKMGDPYSVFTACGVTVLTDARLNQEMATNQEMFPMFPGEEGLFMTAMPDSSIQEPRQRKDFPETWIWLDANVSDSASAVFSLTVPDSLTSWAAFAIIMSENLGLGISAPAELTVFRDFFMSLDLPAFLIRGELLLLEVNLFNYMDVDLEVIVVVAESGMFEFVSTDSADFSVANVRKVLVLSQNFTMLLFPIKATTLGEIPISVKATSVYSSDWLYKTVLVKPEGLQQSFTQTLFLEFLLQQHTLSRKMTFSFPADVVPNSQRASVSAVGDILGPSIGNLDSLIEMPYGCGEQNMIHFAPNTYVLQYLKSTKQAEEQTRRKAMSYMMEAYERELSYQRVDGSFSAFGDSDESGSTWLSAFVLRCFLQARDFISIEPLVMERTAFWLVAHQESDGSFREPGQVIHTELQGGLDGSVSLTAYVLIALLEDAKYESTHKDSVSLALSFLTSRLAQGISSNYSLSLVAYALSLAKSSAAPSALTTLLNRALVIDGVPTWRSPGSVLYDSWQPRSADIEIAAYVLLTMHSLRLMDEGFALMKWLSQQRNHLGGYGSTQDTVMALHALSVYATFSSAESMDLTIRVNEGSGTVATFSIDKSNYLLQQSHDLPIESKDGVDIEVEAEGTGFALFQLTVFYNVMNVRRSLRRRDIHTDEAFYLYVDIMDKEEYHVNLYTCFRLRGGQGLNQTGMAILDVGLLTGFSLAQDGVQIDDTVRRVETPSGRVILYLDKVTTVEQCIEISTVMDFKVAGVQDAVIMIYDYYEPRRRTVRSYTSERRRDMSVCSFCGSDCSLCGTQGFRTDGTPSINNHPLLALSLTTALILLLHIYN", "length": 1487, "header": "tr|A0A8N7UTF1-1|A0A8N7UTF1_DANRE Isoform 1 of CD109 antigen isoform X1 OS=Danio rerio OX=7955 GN=cd109 PE=3 SV=1 CANONICAL=A0A8N7UTF1-1" }, "isoforms": [ { "isoform_ac": "A0A8M3ATH0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTF1/entry#A0A8M3ATH0-1", "sequence": { "sequence": "MEWLQFFGILVCSLVCRGAMVTSSARQNLSYLISVSEVLRCGVPTTLSVTVLSDYPINVTARLTHGKTSVAQTQSTVPAGSSRLLSLPPVFYDDMTYWYPYQLNVEGFSGTHLVFSNSTSMVFSPRCMSIFIQTDKNYYQPGQTVKFRVVSVTPDGKPYSGRTDIFIRDPRGNMIRQWLAVDSFLGVISKELNISQNPPLGSWKITAGVNDVIHERAFTVDYYVLPRFEVKLDVPSVLYCEDTLMGTVTAKYFYGKPVSGFMDVRFVHGFNGIEMRYDHTEMIEGSAEITFDMKDFSTRFNDYSYSYYDGYRPIEFIDVNVNITESATGLMYNSSARVSIVTEKYKLEFLQYPHIVKPSMTFTAKLKLSLYDQRPLSAEDQIESVYLAVTQHKLSPWTWMWSDGGPLGPRMMNNTPSTSFPPNSDGGPLGPHMMNSTPPTSFTPIYDLPVQNIELPVTADGLMSFQIHLSDSVATLDLEARFKDTVQHLQLYRSYSSPSKSYIQLHRDSEPQVGRSLNFTLESSFNLTKIHYLVTSRAGVVDAGTVQSSSFSLNTDHLWAPQACVMVYYTLPDGEIVNDALHVSFTKVLRNTVSVRWSQDRAEPAESVSLSVSVSEPGSVLGILVVDKATLNSAEDNGLSEKTVLEEFLSYSREMTHTDNRGMKMGDPYSVFTACGVTVLTDARLNQEMATNQEMFPMFREEGLFMTAMPDSSIQEPRQRKDFPETWIWLDANVSDSASAVFSLTVPDSLTSWAAFAIIMSENLGLGISAPAELTVFRDFFMSLDLPAFLIRGELLLLEVNLFNYMDVDLEVIVVVAESGMFEFVSTDSADFSVANVRKVLVLSQNFTMLLFPIKATTLGEIPISVKATSVYSSDWLYKTVLVKPEGLQQSFTQTLFLEFLLQQHTLSRKMTFSFPADVVPNSQRASVSAVGDILGPSIGNLDSLIEMPYGCGEQNMIHFAPNTYVLQYLKSTKQAEEQTRRKAMSYMMEAYERELSYQRVDGSFSAFGDSDESGSTWLSAFVLRCFLQARDFISIEPLVMERTAFWLVAHQESDGSFREPGQVIHTELQGGLDGSVSLTAYVLIALLEDAKYESTHKDSVSLALSFLTSRLAQGISSNYSLSLVAYALSLAKSSAAPSALTTLLNRALVIDGVPTWRSPGSVLYDSWQPRSADIEIAAYVLLTMHSLRLMDEGFALMKWLSQQRNHLGGYGSTQDTVMALHALSVYATFSSAESMDLTIRVNEGSGTVATFSIDKSNYLLQQSHDLPIESKDGVDIEVEAEGTGFALFQLTVFYNVMNVRRSLRRRDIHTDEAFYLYVDIMDKEEYHVNLYTCFRLRGGQGLNQTGMAILDVGLLTGFSLAQDGVQIDDTVRRVETPSGRVILYLDKVTTVEQCIEISTVMDFKVAGVQDAVIMIYDYYEPRRRTVRSYTSERRRDMSVCSFCGSDCSLCGTQGFRTDGTPSINNHPLLALSLTTALILLLHIYN", "length": 1486, "header": "tr|A0A8M3ATH0-1|A0A8N7UTF1_DANRE Computationally mapped isoform of CD109 antigen isoform X1 OS=Danio rerio OX=7955 GN=cd109 PE=3 SV=1 CANONICAL=A0A8N7UTF1-1" }, "locus": {} }, { "isoform_ac": "A0A8N7UTF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTF1/entry#A0A8N7UTF1-1", "sequence": { "sequence": "MEWLQFFGILVCSLVCRGAMVTSSARQNLSYLISVSEVLRCGVPTTLSVTVLSDYPINVTARLTHGKTSVAQTQSTVPAGSSRLLSLPPVFYDDMTYWYPYQLNVEGFSGTHLVFSNSTSMVFSPRCMSIFIQTDKNYYQPGQTVKFRVVSVTPDGKPYSGRTDIFIRDPRGNMIRQWLAVDSFLGVISKELNISQNPPLGSWKITAGVNDVIHERAFTVDYYVLPRFEVKLDVPSVLYCEDTLMGTVTAKYFYGKPVSGFMDVRFVHGFNGIEMRYDHTEMIEGSAEITFDMKDFSTRFNDYSYSYYDGYRPIEFIDVNVNITESATGLMYNSSARVSIVTEKYKLEFLQYPHIVKPSMTFTAKLKLSLYDQRPLSAEDQIESVYLAVTQHKLSPWTWMWSDGGPLGPRMMNNTPSTSFPPNSDGGPLGPHMMNSTPPTSFTPIYDLPVQNIELPVTADGLMSFQIHLSDSVATLDLEARFKDTVQHLQLYRSYSSPSKSYIQLHRDSEPQVGRSLNFTLESSFNLTKIHYLVTSRAGVVDAGTVQSSSFSLNTDHLWAPQACVMVYYTLPDGEIVNDALHVSFTKVLRNTVSVRWSQDRAEPAESVSLSVSVSEPGSVLGILVVDKATLNSAEDNGLSEKTVLEEFLSYSREMTHTDNRGMKMGDPYSVFTACGVTVLTDARLNQEMATNQEMFPMFPGEEGLFMTAMPDSSIQEPRQRKDFPETWIWLDANVSDSASAVFSLTVPDSLTSWAAFAIIMSENLGLGISAPAELTVFRDFFMSLDLPAFLIRGELLLLEVNLFNYMDVDLEVIVVVAESGMFEFVSTDSADFSVANVRKVLVLSQNFTMLLFPIKATTLGEIPISVKATSVYSSDWLYKTVLVKPEGLQQSFTQTLFLEFLLQQHTLSRKMTFSFPADVVPNSQRASVSAVGDILGPSIGNLDSLIEMPYGCGEQNMIHFAPNTYVLQYLKSTKQAEEQTRRKAMSYMMEAYERELSYQRVDGSFSAFGDSDESGSTWLSAFVLRCFLQARDFISIEPLVMERTAFWLVAHQESDGSFREPGQVIHTELQGGLDGSVSLTAYVLIALLEDAKYESTHKDSVSLALSFLTSRLAQGISSNYSLSLVAYALSLAKSSAAPSALTTLLNRALVIDGVPTWRSPGSVLYDSWQPRSADIEIAAYVLLTMHSLRLMDEGFALMKWLSQQRNHLGGYGSTQDTVMALHALSVYATFSSAESMDLTIRVNEGSGTVATFSIDKSNYLLQQSHDLPIESKDGVDIEVEAEGTGFALFQLTVFYNVMNVRRSLRRRDIHTDEAFYLYVDIMDKEEYHVNLYTCFRLRGGQGLNQTGMAILDVGLLTGFSLAQDGVQIDDTVRRVETPSGRVILYLDKVTTVEQCIEISTVMDFKVAGVQDAVIMIYDYYEPRRRTVRSYTSERRRDMSVCSFCGSDCSLCGTQGFRTDGTPSINNHPLLALSLTTALILLLHIYN", "length": 1487, "header": "tr|A0A8N7UTF1-1|A0A8N7UTF1_DANRE Isoform 1 of CD109 antigen isoform X1 OS=Danio rerio OX=7955 GN=cd109 PE=3 SV=1 CANONICAL=A0A8N7UTF1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:569058", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569058", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A447-1", "protein_name": "CD109 antigen", "gene_name": "Cd109", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRNPRLLSAAHLLSVCVVAVAAHGSRFLVTVPGIIRPGANMTIGVELLQNSPPQVLVKARVLKIASNRSTTVLEAEGVFNRGHFGILVLPALPLHKANKIYELHISGKSETEIVFSNRTRLTFDSKRISVFIQTDKVIYKPKQEVKFRVLTLFSDLKPYKTPVDIYIKDPKSNLIQQWLSQEGELGVVSKTFQLSSHPILGDWSIQVQVIDQLYYQSFQVLDYVLPKFEVTLQTPLYCSLKAKYLRGNVTAKYTYGKPVKGSLSLTFIPLSFWGKKKNITKNFEINGFTNFAFDADEMKKVMNLKKATEISDGNYDQVDPVFPGPVEIVATVTESLTGTSRKASTNVFFKQHDYVIEIFDYTTVLKPTLNFTATVKISRSDGKQLTPEEMENDLVTVVTQKKNDNPTREKAQGTDYIQMTEYSVPHNGVVKVEFPIMSDSSELQLKASFLDSASSVAVHSVFTSPSNTYIQLKTRDEHITVGSPFNLTVSGNQKFKEISYMVISKGQLVAVGKQSSRTFSLTPEASWAPKACIIVYYIEQDGEVISDILKIPVQLDFKNKIKLSWSKPRVKPSDKVSLRISVTQSYSLVGIVAVDKSVKLIGNSNDITMENVVHELELYNTEYYLGMFLNSFAVFQECGLWVLTDANLVRDNIDEVYDTQEYSERFAEENEANLVDFEDTSSASNSHVRKHFPESWIWLDFYMGSKNHEEYEVTVPDSITSWVASAFVISEDLGFGLTATPAELHAFQPFFISLNLPYSVIRGEEFALEVSIVNYLKDTTKVVVLIEESDSFDILMFSNDINNTIYRKTALVPRENSVTLVFPIKPTHLGNVPITVTAASPTSSDVVTRTIVVKPEGVAKSYSQSVLLELIDKKQQTEPKSLSFSFPPDTISGSERIQITAIGDILGSSINGLSSLIRLPYGCGEQNMVYLAPNVYILDYLTKQKQLTVNLKEKALSFMRQGYQRELLYQREDGSFSAFGNSDSSGSTWLSAFVLRCFMEAAQYIDIDQDVLHRTYSWLEAHKKTNGEFWEPGRVIHIELQGGNKSPITLTAYVVTSLLGYKKYQPNIEIQDSIKFLENEFNRGISDNYTLALVTYALSAVGSPKAEEALTMLTQQAEKEGDTQFWLSSTSESSESWQSLSAQIEIAAYALLAHTQHHVPEGIPIMKWLIKQRNSLGGFVSTQDTVMALKALSEFSALVYKENRDMQVTIKGPNVPKPIRFWIDSQNLFKLHKEELAPLDPIAVNVSAHGSGFAICQLNVDYNVKASSSFKRRRSMENPIGFDLDVDVNDEHDLRYMKLNVCTSHLGPGRTGMALLEVNLLSGFTATSDSIPLSEILKKVEYEPGKLNLYLDHVNETQFCVKIPTVRDFKVSNIRDGLVSIVDYYEPSRQAVRSYNTQMKLSSCYLSADPNCRSYMDRATDSLRHSSSLLVLCSTLLYFVQH", "length": 1442 }, "evidence": [ { "id": "HGNC:21685", "url": "https://alliancegenome.org/gene/HGNC:21685#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-253", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-253#orthology", "database": "AGR" }, { "id": "MGI:2445221", "url": "https://alliancegenome.org/gene/MGI:2445221#orthology", "database": "AGR" }, { "id": "RGD:1311287", "url": "https://alliancegenome.org/gene/RGD:1311287#orthology", "database": "AGR" }, { "id": "FB:FBgn0041180", "url": "https://alliancegenome.org/gene/FB:FBgn0041180#orthology", "database": "AGR" }, { "id": "FB:FBgn0041181", "url": "https://alliancegenome.org/gene/FB:FBgn0041181#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9PDR0-1", "protein_name": "TEP1-F", "gene_name": "Tep4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRRADAFAVSLCVILALLQTMEPVKAEGKYTIVGPGTIHSHRDYNVAVAVHQTKEPVTLKVGITGPSYNKTETVELATAGEFKQITFKLPPLEAGEYNLTAEGVKGLEFKNSTKLNWENFKPYIKIQTDKGKYKPGDTINYRVIFLDENLRPDTAKDEVVVWFEDSKRNRIKQEKHIKTTGGVYTGKFELSEFATLGSWSLHVQNGDQHHDGGIYFGGRKQFGGFGHRWHRSDELVNFEVEKYVLPKYSVKMDATQQVSVRDGEFNVVLKANYTYGKPVNGKVLVNVHLDSTSSWENVDGKTVQTDYPGHSVVGTADMVGGKAKLTMDLKDFASYLPHKTSSSYAQITATVEEDFTGVKLNETGGVQLYPYRYEMSCTDYSSCFSFKPDKEHELNFKITYVDGSLITDTKSVVKAKFTEGIRRNYAFYAFGTDHQEPELPTIEKKTFVFESHLNASGVAPFKVVLPDLPDIANFTRYYSIELEFVDEKRDLYTTYPYREPKQIENPSSEEEKEWFRAEVQRPKDVWNLKIGQEYQVILNSSRPLKYFVYNIVGRGNILETKRVDLAEPQTTVNVTIKPTFLTTPYGRVYFYYVDETGEFRYTEETFSVEVELQNQIEIKAPAEVKPGADVALEIKTSPKSFVGLLAVDQSVLLLGSNNDLNKESFNWRLNGYDTSTPWQGGYSYYPGERTGVVTMTNAYFFYNRTAPDYNILTEGFGGSSFAMRKTTVAHDSHVFHSGAGGPTQAVGFSAESASASAAPVVRKNFAETWIFADIESTEEEVFKWVKTIPDTITNWVVTGFSLHPQKGLGVTNDQTNIKTFQPFFVSVRLPYSVKRGEVINVPALVFNYLPKTLDVELTLDNEDQEYDFVDASNEVIGDQKRTQNIRVGANEAAGASFLIRPKVIGNILLKFKAISPLAGDAIHKPLKVVPEGITQYQNRAFFINLKDTGEFKNTFELEVPEDVVPDSERVEFGLVGDLLGPVVKNLENLLRLPSGCGEQTMSKLVPNYLVRDYLKSIKKLTPALDTRIKRNLQDGYQHMLHYRHDDGSFSSFGPTKWRQEDPVRNGSTWLTAYVLRSFSKIKDIIDLDEQILAKGYEFLLTRQAENGSFTEHGEYFYSSQRSLLTLTANSLLALLEEEKPNQAAIDKAVAYLSANTAESIELLPKSIAIYALQKAKAPEAAKQVASLKSLAKHEDDRTWWTEDLDKLRASKNCGRWWCWIWSQDVEITSYALLSLLDSDQETADSVLNTVRWLIAQRNGFGGFASSQDTVVGLTALIKFAEKSGYEAAKWEVTVSNKGKREKTEKLNTSEENDLLLQTVEFPQGTKSLEFEAKGTGAAMVQISYQYNLVEKEPKPSFKIQTTVLPESSPANLELSVCVDYVEEGESKESNMAILEVSLPSGYTADEDSFADIRNIERVRLVETKNGDSVVVIYFENLAKNEEKCIRIEAYRTHAVANQKPSSVVLYDYYDTNKKATEYYSIKSKLCDICEGDDCKSKC", "length": 1498 }, "evidence": [ { "id": "HGNC:21685", "url": "https://alliancegenome.org/gene/HGNC:21685#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-253", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-253#orthology", "database": "AGR" }, { "id": "MGI:2445221", "url": "https://alliancegenome.org/gene/MGI:2445221#orthology", "database": "AGR" }, { "id": "RGD:1311287", "url": "https://alliancegenome.org/gene/RGD:1311287#orthology", "database": "AGR" }, { "id": "FB:FBgn0041180", "url": "https://alliancegenome.org/gene/FB:FBgn0041180#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q6YHK3-1", "protein_name": "CD109 antigen", "gene_name": "CD109", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGPPLLTAAHLLCVCTAALAVAPGPRFLVTAPGIIRPGGNVTIGVELLEHCPSQVTVKAELLKTASNLTVSVLEAEGVFEKGSFKTLTLPSLPLNSADEIYELRVTGRTQDEILFSNSTRLSFETKRISVFIQTDKALYKPKQEVKFRIVTLFSDFKPYKTSLNILIKDPKSNLIQQWLSQQSDLGVISKTFQLSSHPILGDWSIQVQVNDQTYYQSFQVSEYVLPKFEVTLQTPLYCSMNSKHLNGTITAKYTYGKPVKGDVTLTFLPLSFWGKKKNITKTFKINGSANFSFNDEEMKNVMDSSNGLSEYLDLSSPGPVEILTTVTESVTGISRNVSTNVFFKQHDYIIEFFDYTTVLKPSLNFTATVKVTRADGNQLTLEERRNNVVITVTQRNYTEYWSGSNSGNQKMEAVQKINYTVPQSGTFKIEFPILEDSSELQLKAYFLGSKSSMAVHSLFKSPSKTYIQLKTRDENIKVGSPFELVVSGNKRLKELSYMVVSRGQLVAVGKQNSTMFSLTPENSWTPKACVIVYYIEDDGEIISDVLKIPVQLVFKNKIKLYWSKVKAEPSEKVSLRISVTQPDSIVGIVAVDKSVNLMNASNDITMENVVHELELYNTGYYLGMFMNSFAVFQECGLWVLTDANLTKDYIDGVYDNAEYAERFMEENEGHIVDIHDFSLGSSPHVRKHFPETWIWLDTNMGYRIYQEFEVTVPDSITSWVATGFVISEDLGLGLTTTPVELQAFQPFFIFLNLPYSVIRGEEFALEITIFNYLKDATEVKVIIEKSDKFDILMTSNEINATGHQQTLLVPSEDGATVLFPIRPTHLGEIPITVTALSPTASDAVTQMILVKAEGIEKSYSQSILLDLTDNRLQSTLKTLSFSFPPNTVTGSERVQITAIGDVLGPSINGLASLIRMPYGCGEQNMINFAPNIYILDYLTKKKQLTDNLKEKALSFMRQGYQRELLYQREDGSFSAFGNYDPSGSTWLSAFVLRCFLEADPYIDIDQNVLHRTYTWLKGHQKSNGEFWDPGRVIHSELQGGNKSPVTLTAYIVTSLLGYRKYQPNIDVQESIHFLESEFSRGISDNYTLALITYALSSVGSPKAKEALNMLTWRAEQEGGMQFWVSSESKLSDSWQPRSLDIEVAAYALLSHFLQFQTSEGIPIMRWLSRQRNSLGGFASTQDTTVALKALSEFAALMNTERTNIQVTVTGPSSPSPVKFLIDTHNRLLLQTAELAVVQPTAVNISANGFGFAICQLNVVYNVKASGSSRRRRSIQNQEAFDLDVAVKENKDDLNHVDLNVCTSFSGPGRSGMALMEVNLLSGFMVPSEAISLSETVKKVEYDHGKLNLYLDSVNETQFCVNIPAVRNFKVSNTQDASVSIVDYYEPRRQAVRSYNSEVKLSSCDLCSDVQGCRPCEDGASGSHHHSSVIFIFCFKLLYFMELWL", "length": 1445 }, "evidence": [ { "id": "HGNC:21685", "url": "https://alliancegenome.org/gene/HGNC:21685#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-253", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-253#orthology", "database": "AGR" }, { "id": "MGI:2445221", "url": "https://alliancegenome.org/gene/MGI:2445221#orthology", "database": "AGR" }, { "id": "RGD:1311287", "url": "https://alliancegenome.org/gene/RGD:1311287#orthology", "database": "AGR" }, { "id": "FB:FBgn0041180", "url": "https://alliancegenome.org/gene/FB:FBgn0041180#orthology", "database": "AGR" }, { "id": "FB:FBgn0041181", "url": "https://alliancegenome.org/gene/FB:FBgn0041181#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R422-1", "protein_name": "CD109 antigen", "gene_name": "Cd109", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRSRRLLSAAHLLCLCAVALAAPGSRFLVTAPGIIRPGANVTIGVDLLENSPPQVLVKAQVFKIASNKSRSILEAEGVFHRGHFKTLVLPALPLSSADKIYELHINGQSENEIVFSNRTRLTFESKSISVLIQTDKAFYKPKQEVKFRVLTLCSDLKPYRTSVDIFIKDPKSNVIQQWFSQKGDLGVVSKTFQLSSNPIFGDWSIQVQVNDQQYYQSFQVLEYVLPKFEVTVQTPLYCSLKSKQLNGSVIAKYTYGKPVKGSLSLTFLPLSFWGKKKNITKSFEINGFANFSFDNYEMKKVMNLKPLTDVSEGSYENVDPSFPGPAEIIATVTESLTGISRMASTNVFFKQHDYIIEIFDYTTVLKPSLNFTATVKVSRSDGNQLTPEEIENDLVTVVTQRKNNHPESQRDQEMDYIQTVNYTIPQNGIIKIEFPVMSISGELQLKAYFLDGTSSVTVHSMFTSPSKTYIQLKTRDEYIKVGSPFDLMVSGNRQFKDLSYMVISKGQLVAAGKQSSRTFSLTPEASWAPKACIIAYYIAEDGEIINDILKIPVQLVFENKVKLFWSKPTVKPSDKVSLRISATQSDSLVGIVAVDKSVTLMENSNSITMETMVHELELYNTEYYLGMFMNSFAVFQECGLWVLTDATLIRDSIDEVYDTEEYSERFAEENEANLVDFEDASSVNNVHVRKNFPETWIWLDAYMGSKIYEEFEVTVPDSITSWVASAFVISEDLGFGLTTVPAELQAFQPFFLFLNLPYSVIRGEEFALEVSIVNYLKDTIKVVILIEESDSFDILMTSNDTNGTIYRKTVQVPRDNGVTLVFPIKPTHLGEIPITVTAASPTASDAVTQTIVVKPEGIEKSYSKSVLLDLTDSNVESKQQSMRFSFPPDTVIGSERVQITAIGDILGSSINGLSSLIRMPYGCGEQNMIYFAPNIYILDYLTKQKQLTVNLKEKALSYMRQGYQRELLYQREDGSFSAFGDIDSSGSTWLSAFVLRCFLEADYYIDIDQDVLHRTYTWLNAHKKFNGEFWEPGRVIHSELQGGTKSPVTLTAYIVTSVLGYKKYQPNIDVQDSIKFLEFEFSRGISDNYTLAIISYALSTVGSPKAEEALNLLMQRSEKEGDTQFWLSSGPALSGSWQPRSVDIEIAAYALLAHTLHHVSEGIPVMRWLIQQRNSLGGFVSTQDTVVALKALSEFSALVHKENTDIQLTVTGPGIPRSIHFRIDSQNLFLLHQEELHALDPITVNVSAHGSGFAICQLNVDYNVKGSGSSKRRRSTENQEVFDLDVIVNNEDDISHLNLNVCTSHLGSERTGMVLMEVNLLSGFSASSDSIPLSETLKKVEYDNGKLNLYLDSVNESQFCVNIPTVRDYKVSNIRDGSVSVMDYYEPRRQAVRSYNTQVKLSSCYLSPDTNCKSHTDGATDSLRRSSSLLVFCSVLLYFVQH", "length": 1442 }, "evidence": [ { "id": "HGNC:21685", "url": "https://alliancegenome.org/gene/HGNC:21685#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-253", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-253#orthology", "database": "AGR" }, { "id": "MGI:2445221", "url": "https://alliancegenome.org/gene/MGI:2445221#orthology", "database": "AGR" }, { "id": "RGD:1311287", "url": "https://alliancegenome.org/gene/RGD:1311287#orthology", "database": "AGR" }, { "id": "FB:FBgn0041180", "url": "https://alliancegenome.org/gene/FB:FBgn0041180#orthology", "database": "AGR" }, { "id": "FB:FBgn0041181", "url": "https://alliancegenome.org/gene/FB:FBgn0041181#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VLY7-1", "protein_name": "TEP1-F", "gene_name": "Tep3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRLQGADMGAIPVLILVTACLLCQTSAQGLYSIIAPNTLRPNSQFHVAVSLHNAPESATFKVGILGSSYTDFKTVELRPFSTQLLHFEIPALRTDRYRLTAEGLGGVQFTNETQLHFESKQHTVLVQTDKSIYKPGDLVHYRVLILDANLKPARGYGRVHVDIKDSGDNIIRSYKDIRLTNSIYSNELRLSDSPRFGTWSIVVDVSDQEHTQTFEILDHILPKFVVDIDTPKHAIYKDGKIAATVRAHYAFGQPIVGEATLSIYPTFFGSLQPFVNDLITRKVVPIDGNAYFEFDIENELHLKQDYERQYLLDALVEEKSTGSVQNYSTVLTLHLNHYRVEAVKVPSYYIPGVPFEATARIARNDGGQLRDFNPQITAYLTNVYGSSEMYNRTAYSLDASGEIKMKFTVPIGDRDEFHSIIVDYQGVISEVGKIPSKHLHSKNYITAKVLNDRPTVNQEISVVVRSFAPIKYFMYQVVGRGDIILSRNVDVAPGTFHTIKFLASFAMMPRANLLVYTVIDGEFVYDEQVIQLEENLLNAVQVDAPIRAPPGQDIDIGISTKPYSYVGLMLVDQNANDLRSGHDLTHKRLMDALRSYELSDVNTPMGSPGKESGVITMSNTDYFIEKEAESNPALDREVSTGPEEDKLTTVRKTDIGPAHKIEVNTLPPGKGRYAFSYTPKPFWHNPRVHVMRDPADTWLFLNISASSDGRNSIHRRIPSEMTSWVVSAFALDPVNGLGLSPPNGKLEAYKEFYISTELPYSIKRDELIAIPFVVHNNRDSDLNVEVTFYNSALDFDFPQLDPKATNQPKVELYRRRSLQVPGRSARSVSFIVTPKRVGPLLVKAMAASSQAGDTVEQNLLVEHPGAMERINRGFLFELNSNAQNRRNVTIAVPRNAIPESTRIEVSAVGDLIGSLVGNLDSLILLPTGCGEQTMVNFVPNLIVLRYLGRLRQLTPEVELRATNNLAIGYQRILYYRHENGAFSAFGLDIKRSSTWLTAYVARSLRQAAPFTQVDSNVLQKALTYLGSVQSANGGFEERGDVFERFGDDGISLTAFVTLALMENVDLYPEYRNNINKALDFITRGLDGSSNLHAMAIGTYVLSRANHNAKAAFLQRLDSMATNKDGLKWWNKTAPAGEQQSPWYNATRSVNIEISAYAALALLENNLVGDALPVLNWLMDQRNPKGGFVASQDTVVGLQALLMFAERFSSQGNNLQIGFHYGEGAETIINVNAENSLALQTVELPNNLKNLSVSATGRGMALAQVSYTYNTNVTSAWPRFVLDPTVNRNSHADYLHLSACASFVSVVGENEQRSNMAVMEVHLPSGFVVDRDTLPTLESSERIKKVETQNRNTKVVIYFDYLDRREVCPTLHAYKTVKVTKHRPVAVVMYDYYDSARRARQFYRAPKSNICDICEHANCGDLCEKAEKRESKRPDDYTAIAGHSSGSRHTAIPLASVVMVLSMLLKTLSC", "length": 1469 }, "evidence": [ { "id": "HGNC:21685", "url": "https://alliancegenome.org/gene/HGNC:21685#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-253", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-253#orthology", "database": "AGR" }, { "id": "MGI:2445221", "url": "https://alliancegenome.org/gene/MGI:2445221#orthology", "database": "AGR" }, { "id": "RGD:1311287", "url": "https://alliancegenome.org/gene/RGD:1311287#orthology", "database": "AGR" }, { "id": "FB:FBgn0041181", "url": "https://alliancegenome.org/gene/FB:FBgn0041181#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UTF1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTF1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UTF1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1120, "end_pos": 1122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1345, "end_pos": 1347, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 526, "end_pos": 528, "annotation": "n_glycosylation_sequon" }, { "start_pos": 58, "end_pos": 60, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 847, "end_pos": 849, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UTF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTF1" }, { "id": "SM01360", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01360" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": 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"differentially expressed in FDCP 6 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_692142", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692142" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_692142.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_692142", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692142" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "def6c", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-87", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-87", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVA8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UVA8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13273", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13273", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "563690", "url": "https://www.ncbi.nlm.nih.gov/gene/563690", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057836", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057836", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3B1R8", "url": "https://www.orthodb.org/?gene=A0A8M3B1R8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVA8", "url": "https://www.orthodb.org/?gene=A0A8N7UVA8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14383", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14383", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14383:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14383:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25530", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25530", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_692142", "url": 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"MDLKSELLKSVWYAFTSLDVEQSGKVSKSQLKVLSHNLYTVLNIPHDPVALEEHFKDNNNGPVSSHGYMPYLNKYILAKVIDGTFNKEIFDELCWTMSSKKNCKPSVQQGLCSQRDCFKLFCLFNLLSEDRYPLVIIQPELEYLLKKISSAMSLEWDSTLLEELLSKNVDLQDGVSVWEFLEHLSAGQLLHVESKEAFSLAVDEVFMEMYHSIIKKGYLVKKGHVRRNWQERWFVLKPGSLIYYVAEDQKEKKGEILLEESSVVESVPDKEGRRCLFCVKTSVRTYEMSASNLKQRVDWMQAIQMAFRLRAEGKSSLHQDLKLSRRKQRETLQRSQSNQSTHNESSAVEASQHSAPEQQGETESLEQHIESIIQKQREVEAKCKEEEKQEHEKQQAIQRDLEKQLEEAKEANEKMTMTLTEMEKEVQQHKKRINELELTQVKLEEALNTQIHARLEEDRARQELERQLAEEQKKLADLLLLQQQMQTASVRVQVEPQINDDTSVEAAPISQHAEESSQQNTVEPLISETTFASTPPNVQQPEESHQYTTERELENQSSTQMMKHWKIQLNRLMKPIAPGDKAEHLPVKSGCPRKGHALTSTEFISKVQTGTASPPQQQEE", "length": 620, "header": "tr|A0A8N7UVA8-1|A0A8N7UVA8_DANRE Isoform 1 of Differentially expressed in FDCP 6 homolog isoform X1 OS=Danio rerio OX=7955 GN=def6c PE=4 SV=1 CANONICAL=A0A8N7UVA8-1" }, "isoforms": [ { "isoform_ac": "A0A8M3B1R8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA8/entry#A0A8M3B1R8-1", "sequence": { "sequence": "MPYLNKYILAKVIDGTFNKEIFDELCWTMSSKKNCKPSVQQGLCSQRDCFKLFCLFNLLSEDRYPLVIIQPELEYLLKKISSAMSLEWDSTLLEELLSKNVDLQDGVSVWEFLEHLSAGQLLHVESKEAFSLAVDEVFMEMYHSIIKKGYLVKKGHVRRNWQERWFVLKPGSLIYYVAEDQKEKKGEILLEESSVVESVPDKEGRRCLFCVKTSVRTYEMSASNLKQRVDWMQAIQMAFRLRAEGKSSLHQDLKLSRRKQRETLQRSQSNQSTHNESSAVEASQHSAPEQQGETESLEQHIESIIQKQREVEAKCKEEEKQEHEKQQAIQRDLEKQLEEAKEANEKMTMTLTEMEKEVQQHKKRINELELTQVKLEEALNTQIHARLEEDRARQELERQLAEEQKKLADLLLLQQQMQTASVRVQVEPQINDDTSVEAAPISQHAEESSQQNTVEPLISETTFASTPPNVQQPEESHQYTTERELENQSSTQMMKHWKIQLNRLMKPIAPGDKAEHLPVKSGCPRKGHALTSTEFISKVQTGTASPPQQQEE", "length": 552, "header": "tr|A0A8M3B1R8-1|A0A8N7UVA8_DANRE Computationally mapped isoform of Differentially expressed in FDCP 6 homolog isoform X1 OS=Danio rerio OX=7955 GN=def6c PE=4 SV=1 CANONICAL=A0A8N7UVA8-1" }, "locus": {} }, { "isoform_ac": "A0A8N7UVA8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA8/entry#A0A8N7UVA8-1", "sequence": { "sequence": "MDLKSELLKSVWYAFTSLDVEQSGKVSKSQLKVLSHNLYTVLNIPHDPVALEEHFKDNNNGPVSSHGYMPYLNKYILAKVIDGTFNKEIFDELCWTMSSKKNCKPSVQQGLCSQRDCFKLFCLFNLLSEDRYPLVIIQPELEYLLKKISSAMSLEWDSTLLEELLSKNVDLQDGVSVWEFLEHLSAGQLLHVESKEAFSLAVDEVFMEMYHSIIKKGYLVKKGHVRRNWQERWFVLKPGSLIYYVAEDQKEKKGEILLEESSVVESVPDKEGRRCLFCVKTSVRTYEMSASNLKQRVDWMQAIQMAFRLRAEGKSSLHQDLKLSRRKQRETLQRSQSNQSTHNESSAVEASQHSAPEQQGETESLEQHIESIIQKQREVEAKCKEEEKQEHEKQQAIQRDLEKQLEEAKEANEKMTMTLTEMEKEVQQHKKRINELELTQVKLEEALNTQIHARLEEDRARQELERQLAEEQKKLADLLLLQQQMQTASVRVQVEPQINDDTSVEAAPISQHAEESSQQNTVEPLISETTFASTPPNVQQPEESHQYTTERELENQSSTQMMKHWKIQLNRLMKPIAPGDKAEHLPVKSGCPRKGHALTSTEFISKVQTGTASPPQQQEE", "length": 620, "header": "tr|A0A8N7UVA8-1|A0A8N7UVA8_DANRE Isoform 1 of Differentially expressed in FDCP 6 homolog isoform X1 OS=Danio rerio OX=7955 GN=def6c PE=4 SV=1 CANONICAL=A0A8N7UVA8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UUX7-1", "uniprot_ac": "A0A8N7UUX7", "uniprot_id": "A0A8N7UUX7_DANRE", "mass": { "chemical_mass": 129803.0, "monoisotopic_mass": 129803.0 }, "refseq": { "ac": "XP_690638", "name": "partitioning defective 3 homolog B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690638" }, "gene_names": [ { "name": "pard3bb", "type": "recommended", "evidence": [ { "id": "A0A8N7UUX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ] }, { "name": "pard3bb", "type": "synonym", "evidence": [ { "id": "XP_690638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690638" } ] } ], "protein_names": [ { "name": "Partitioning defective 3 homolog B isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UUX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7/entry#names_and_taxonomy" } ] }, { "name": "partitioning defective 3 homolog B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_690638", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690638" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_690638.6. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_690638", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690638" } ] } ], "disease": [ { "disease_id": "DOID:0060037", "recommended_name": { "id": "DOID:0060037", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060037", "name": "developmental disorder of mental health", "description": "A disease of mental health that occur during a child's developmental period between birth and age 18 resulting in retarding of the child's psychological or physical development." }, "synonyms": [], "unlinked_id_list": [ "DOID:4090", "DOID:2769", "DOID:92" ], "evidence": [ { "id": "0060037", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060037" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "pard3bb", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-290", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-290", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUX7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UUX7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06691", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06691", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23058", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23058", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd23059", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23059", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "562146", "url": "https://www.ncbi.nlm.nih.gov/gene/562146", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562146", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562146", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M3B2I8", "url": "https://www.orthodb.org/?gene=A0A8M3B2I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUX7", "url": "https://www.orthodb.org/?gene=A0A8N7UUX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16484", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16484", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16484:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16484:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12053", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12053", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_690638", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690638", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3B2I8", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B2I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B2I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B2I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QFU7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QFU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QFU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QK08", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QK08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QK08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QK08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GFZ5", "url": "https://www.uniprot.org/uniprotkb/A0AC58GFZ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GFZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GFZ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-290", "url": "https://zfin.org/ZDB-GENE-070912-290", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKVTVTFGRTGVVVPCKEGWTVRDLILQATQRYRKLLEQEGDFLVRTHHVEYCDGGILDPDDVLTDLVEDKDKLIAVYEEQEAQQRGAMSPGNGSGARSSLTGQSSPEPYDSELACFQPIKGGEIEVTSSALKSSTPLLVRSSSDSALGASQMEDMNSRAMGIHVQTDMDFTAELTGNKSGPLTSNLTKTVEISGEQGPLGIHVVPYCSSLSGRPLGLHIRGVEENSRSKREGIFQDDECIVKINDTELMDKSFSQAQEIFRQAMRSSIVRLEVVPVFNKERFEKSVISHLFNPETPDASARTKEPPPLKVKPMVRPVESSSGWQAEFQESSSSLESRSLGSPLPINLSPTPRGKSAENSLLKNSLGPSPLQNHNKKGGKRLRIDLKKGPEGLGFTVVTRDSSVHGPGPILVKNILPRGAAVKDGRLQSGDRILEVNGVDIGGRSQEELVAMLRSTKQGDSVCLVVARQEDMFLPRELKEEQARLLLSEEGKEQLMFEVPLNDSGSAGLGVSLKGNKSRETGEDLGIFIKSIIHGGAAFKDGRLRINDQLIAVNGEPLLGKSNHEAMETLRRSMSMEGNLRGMIQLVVLRSVLPPNQEFQEARRILNRSFDSCVGQAAHLSQSDAGVQPPMVMNSIYERCAVSNGGYNHTEEGDDEGFDANPHRQNSLQFQQSLLSSGLRSADASLTDGGQQVHAEQNHVKSLKSVDLVSGGVVLGPTLGLKKSSSLESLQTAMTEAKKNELLPFHRPRPHIVRGRGCNESFRAAIDKSYDGPPEDDDDEGSEQSSGRDTPASGSSRQGAGDNEENKKDKKKKAKSKKKEKMKSKGKEKEKKKSEEIGDELDKKTKKKGFGLLRFGKKKEEKSKPETKVNALKQTAEILSEEELERMKEERERIEAKHQELRERQGRDRFSPPDLEDDDLDPNYARINNFKERGSPSQPLYGNRSPSPQRPLAAVSHSREPSTEDPLDGLYAKVNKQRSPPPPAADSSMDRIQQLRREYLQARREGTAPAYDELEARRRGAEHDPHRMPMRNPDPRLAPRYEDVERQYASLPRRAPADPNEYPVQQWSAHREPAQYPNPQSGYHPGYPPPPREAYPRPLDPRQGDAGFYHPLPQQRGPLRQDVPPSPTIPIRGPRFDTMSRGGYRNTSPERYAYGDQRHSDPRQKSPMTAAV", "length": 1172, "header": "tr|A0A8N7UUX7-1|A0A8N7UUX7_DANRE Isoform 1 of Partitioning defective 3 homolog B isoform X1 OS=Danio rerio OX=7955 GN=pard3bb PE=3 SV=2 CANONICAL=A0A8N7UUX7-1" }, "isoforms": [ { "isoform_ac": "A0A8M3B2I8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7/entry#A0A8M3B2I8-1", "sequence": { "sequence": "MKVTVTFGRTGVVVPCKEGWTVRDLILQATQRYRKLLEQEGDFLVRTHHVEYCDGGILDPDDVLTDLVEDKDKLIAVYEEQEAQQRGAMSPGNGSGARSSLTGQSSPEPYDSELACFQPIKGGEIEVTSSALKSSTPLLVRSSSDSALGASQMEDMNSRAMGIHVQTDMDFTAELTGNKSGPLTSNLTKTVEISGEQGPLGIHVVPYCSSLSGRPLGLHIRGVEENSRSKREGIFQDDECIVKINDTELMDKSFSQAQEIFRQAMRSSIVRLEVVPVFNKERFEKSVISHLFNPETPDASARTKEPPPLKVKPMVRPVESSSGWQAEFQESSSSLESRSLGSPLPINLSPTPRGKSAENSLLKNSLGPSPLQNHNKKGGKRLRIDLKKGPEGLGFTVVTRDSSVHGPGPILVKNILPRGAAVKDGRLQSGDRILEVNGVDIGGRSQEELVAMLRSTKQGDSVCLVVARQEDMFLPRELKEEQARLLLSEEGKEQLMFEVPLNDSGSAGLGVSLKGNKSRETGEDLGIFIKSIIHGGAAFKDGRLRINDQLIAVNGEPLLGKSNHEAMETLRRSMSMEGNLRGMIQLVVLRSVLPPNQEFQEARRILNRSFDSCVGQAAHLSQSDAGVQPPMVMNSIYERCAVSNGGYNHTEEGDDEGFDANPHRQNSLQFQQSLLSSGLRSADASLTDGGQQVHAEQNHVKSLKSVDLVSGGVVLGPTLGLKKSSSLESLQTAMTEAKKNELLPFHRPRPHIVRGRGCNESFRAAIDKSYDGPPEDDDDEGSEQSSGRDTPASGSSRQGAGDNEENKKDKKKKAKSKKKEKMKSKGKEKEKKKSEEIGDELDKKTKKKGFGLLRFGKKKEEKSKPETKVNALKQTAEILSEEELERMKEERERIEAKHQELRERQGRDRFSPPDLEDDDLDPNYARINNFKERGSPSQPLYGNRSPSPQRPLAAVSHSREPSTEDPLDGLYAKVNKQRSPPPPAADSMDRIQQLRREYLQARREGTAPAYDELEARRRGAEHDPHRMPMRNPDPRLAPRYEDVERQYASLPRRAPADPNEYPVQQWSAHREPAQYPNPQSGYHPGYPPPPREAYPRPLDPRQGDAGFYHPLPQQRGPLRQDVPPSPTIPIRGPRFDTMSRGGYRNTSPERYAYGDQRHSDPRQKSPMTAAV", "length": 1171, "header": "tr|A0A8M3B2I8-1|A0A8N7UUX7_DANRE Computationally mapped isoform of Partitioning defective 3 homolog B isoform X1 OS=Danio rerio OX=7955 GN=pard3bb PE=3 SV=2 CANONICAL=A0A8N7UUX7-1" }, "locus": {} }, { "isoform_ac": "A0A8M9QFU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7/entry#A0A8M9QFU7-1", "sequence": { "sequence": "MLGSLDVLYSALIHKLIAVYEEQEAQQRGAMSPGNGSGARSSLTGQSSPEPYDSELACFQPIKGGEIEVTSSALKSSTPLLVRSSSDSALGASQMEDMNSRAMGIHVQTDMDFTAELTGNKSGPLTSNLTKTVEISGEQGPLGIHVVPYCSSLSGRPLGLHIRGVEENSRSKREGIFQDDECIVKINDTELMDKSFSQAQEIFRQAMRSSIVRLEVVPVFNKERFEKSVISHLFNPETPDASARTKEPPPLKVKPMVRPVESSSGWQAEFQESSSSLESRSLGSPLPINLSPTPRGKSAENSLLKNSLGPSPLQNHNKKGGKRLRIDLKKGPEGLGFTVVTRDSSVHGPGPILVKNILPRGAAVKDGRLQSGDRILEVNGVDIGGRSQEELVAMLRSTKQGDSVCLVVARQEDMFLPRELKEEQARLLLSEEGKEQLMFEVPLNDSGSAGLGVSLKGNKSRETGEDLGIFIKSIIHGGAAFKDGRLRINDQLIAVNGEPLLGKSNHEAMETLRRSMSMEGNLRGMIQLVVLRSVLPPNQEFQEARRILNRSFDSCVGQAAHLSQSDAGVQPPMVMNSIYERCAVSNGGYNHTEEGDDEGFDANPHRQNSLQFQQSLLSSGLRSADASLTDGGQQVHAEQNHVKSLKSVDLVSGGVVLGPTLGLKKSSSLESLQTAMTEAKKNELLPFHRPRPHIVRGRGCNESFRAAIDKSYDGPPEDDDDEGSEQSSGRDTPASGSSRQGAGDNEENKKDKKKKAKSKKKEKMKSKGKEKEKKKSEEIGDELDKKTKKKGFGLLRFGKKKEEKSKPETKVNALKQTAEILSEEELERMKEERERIEAKHQELRERQGRDRFSPPDLEDDDLDPNYARINNFKERGSPSQPLYGNRSPSPQRPLAAVSHSREPSTEDPLDGLYAKVNKQRSPPPPAADSSMDRIQQLRREYLQARREGTAPAYDELEARRRGAEHDPHRMPMRNPDPRLAPRYEDVERQYASLPRRAPADPNEYPVQQWSAHREPAQYPNPQSGYHPGYPPPPREAYPRPLDPRQGDAGFYHPLPQQRGPLRQDVPPSPTIPIRGPRFDTMSRGGYRNTSPERYAYGDQRHSDPRQKSPMTAAV", "length": 1114, "header": "tr|A0A8M9QFU7-1|A0A8N7UUX7_DANRE Computationally mapped isoform of Partitioning defective 3 homolog B isoform X1 OS=Danio rerio OX=7955 GN=pard3bb PE=3 SV=2 CANONICAL=A0A8N7UUX7-1" }, "locus": {} }, { "isoform_ac": "A0A8M9QK08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7/entry#A0A8M9QK08-1", "sequence": { "sequence": "MKVTVTFGRTGVVVPCKEGWTVRDLILQATQRYRKLLEQEGDFLVRTHHVEYCDGGILDPDDVLTDLVEDKDKLIAVYEEQEAQQRGAMSPGNGSGARSSLTGQSSPEPYDSELACFQPIKGGEIEVTSSALKSSTPLLVRSSSDSALGASQMEDMNSRAMGIHVQTDMDFTAELTGNKSGPLTSNLTKTVEISGEQGPLGIHVVPYCSSLSGRPLGLHIRGVEENSRSKREGIFQDDECIVKINDTELMDKSFSQAQEIFRQAMRSSIVRLEVVPVFNKERFEKSVISHLFNPETPDASARTKEPPPLKVKPMVRPVESSSGWQAEFQESSSSLESRSLGSPLPINLSPTPRGKSAENSLLKNSLGPSPLQNHNKKGGKRLRIDLKKGPEGLGFTVVTRDSSVHGPGPILVKNILPRGAAVKDGRLQSGDRILEVNGVDIGGRSQEELVAMLRSTKQGDSVCLVVARQEDMFLPRELKEEQARLLLSEEGKEQLMFEVPLNDSGSAGLGVSLKGNKSRETGEDLGIFIKSIIHGGAAFKEFQEARRILNRSFDSCVGQAAHLSQSDAGVQPPMVMNSIYERCAVSNGGYNHTEEGDDEGFDANPHRQNSLQFQQSLLSSGLRSADASLTDGGQQVHAEQNHVKSLKSVDLVSGGVVLGPTLGLKKSSSLESLQTAMTEAKKNELLPFHRPRPHIVRGRGCNESFRAAIDKSYDGPPEDDDDEGSEQSSGRDTPASGSSRQGAGDNEENKKDKKKKAKSKKKEKMKSKGKEKEKKKSEEIGDELDKKTKKKGFGLLRFGKKKEEKSKPETKVNALKQTAEILSEEELERMKEERERIEAKHQELRERQGRDRFSPPDLEDDDLDPNYARINNFKERGSPSQPLYGNRSPSPQRPLAAVSHSREPSTEDPLDGLYAKVNKQRSPPPPAADSSMDRIQQLRREYLQARREGTAPAYDELEARRRGAEHDPHRMPMRNPDPRLAPRYEDVERQYASLPRRAPADPNEYPVQQWSAHREPAQYPNPQSGYHPGYPPPPREAYPRPLDPRQGDAGFYHPLPQQRGPLRQDVPPSPTIPIRGPRFDTMSRGGYRNTSPERYAYGDQRHSDPRQKSPMTAAV", "length": 1115, "header": "tr|A0A8M9QK08-1|A0A8N7UUX7_DANRE Computationally mapped isoform of Partitioning defective 3 homolog B isoform X1 OS=Danio rerio OX=7955 GN=pard3bb PE=3 SV=2 CANONICAL=A0A8N7UUX7-1" }, "locus": {} }, { "isoform_ac": "A0A8N7UUX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7/entry#A0A8N7UUX7-1", "sequence": { "sequence": "MKVTVTFGRTGVVVPCKEGWTVRDLILQATQRYRKLLEQEGDFLVRTHHVEYCDGGILDPDDVLTDLVEDKDKLIAVYEEQEAQQRGAMSPGNGSGARSSLTGQSSPEPYDSELACFQPIKGGEIEVTSSALKSSTPLLVRSSSDSALGASQMEDMNSRAMGIHVQTDMDFTAELTGNKSGPLTSNLTKTVEISGEQGPLGIHVVPYCSSLSGRPLGLHIRGVEENSRSKREGIFQDDECIVKINDTELMDKSFSQAQEIFRQAMRSSIVRLEVVPVFNKERFEKSVISHLFNPETPDASARTKEPPPLKVKPMVRPVESSSGWQAEFQESSSSLESRSLGSPLPINLSPTPRGKSAENSLLKNSLGPSPLQNHNKKGGKRLRIDLKKGPEGLGFTVVTRDSSVHGPGPILVKNILPRGAAVKDGRLQSGDRILEVNGVDIGGRSQEELVAMLRSTKQGDSVCLVVARQEDMFLPRELKEEQARLLLSEEGKEQLMFEVPLNDSGSAGLGVSLKGNKSRETGEDLGIFIKSIIHGGAAFKDGRLRINDQLIAVNGEPLLGKSNHEAMETLRRSMSMEGNLRGMIQLVVLRSVLPPNQEFQEARRILNRSFDSCVGQAAHLSQSDAGVQPPMVMNSIYERCAVSNGGYNHTEEGDDEGFDANPHRQNSLQFQQSLLSSGLRSADASLTDGGQQVHAEQNHVKSLKSVDLVSGGVVLGPTLGLKKSSSLESLQTAMTEAKKNELLPFHRPRPHIVRGRGCNESFRAAIDKSYDGPPEDDDDEGSEQSSGRDTPASGSSRQGAGDNEENKKDKKKKAKSKKKEKMKSKGKEKEKKKSEEIGDELDKKTKKKGFGLLRFGKKKEEKSKPETKVNALKQTAEILSEEELERMKEERERIEAKHQELRERQGRDRFSPPDLEDDDLDPNYARINNFKERGSPSQPLYGNRSPSPQRPLAAVSHSREPSTEDPLDGLYAKVNKQRSPPPPAADSSMDRIQQLRREYLQARREGTAPAYDELEARRRGAEHDPHRMPMRNPDPRLAPRYEDVERQYASLPRRAPADPNEYPVQQWSAHREPAQYPNPQSGYHPGYPPPPREAYPRPLDPRQGDAGFYHPLPQQRGPLRQDVPPSPTIPIRGPRFDTMSRGGYRNTSPERYAYGDQRHSDPRQKSPMTAAV", "length": 1172, "header": "tr|A0A8N7UUX7-1|A0A8N7UUX7_DANRE Isoform 1 of Partitioning defective 3 homolog B isoform X1 OS=Danio rerio OX=7955 GN=pard3bb PE=3 SV=2 CANONICAL=A0A8N7UUX7-1" }, "locus": {} }, { "isoform_ac": "A0AC58GFZ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7/entry#A0AC58GFZ5-1", "sequence": { "sequence": "MKVTVTFGRTGVVVPCKEGWTVRDLILQATQRYRKLLEQEGDFLVRTHHVEYCDGGILDPDDVLTDLVEDKDKLIAVYEEQEAQQRGAMSPGNGSGARSSLTGQSSPEPYDSELACFQPIKGGEIEVTSSALKSSTPLLVRSSSDSALGASQMEDMNSRAMGIHVQTDMDFTAELTGNKSGPLTSNLTKTVEISGEQGPLGIHVVPYCSSLSGRPLGLHIRGVEENSRSKREGIFQDDECIVKINDTELMDKSFSQAQEIFRQAMRSSIVRLEVVPVFNKERFEKSVISHLFNPETPDASARTKEPPPLKVKPMVRPVESSSGWQAEFQESSSSLESRSLGSPLPINLSPTPRGKSAENSLLKNSLGPSPLQNHNKKGGKRLRIDLKKGPEGLGFTVVTRDSSVHGPGPILVKNILPRGAAVKDGRLQSGDRILEVNGVDIGGRSQEELVAMLRSTKQGDSVCLVVARQEDMFLPRELKEEQARLLLSEEGKEQLMFEVPLNDSGSAGLGVSLKGNKSRETGEDLGIFIKSIIHGGAAFKEFQEARRILNRSFDSCVGQAAHLSQSDAGVQPPMVMNSIYERCAVSNGGYNHTEEGDDEGFDANPHRQNSLQFQQSLLSSGLRSADASLTDGGQQVHAEQNHVKSLKSVDLVSGGVVLGPTLGLKKSSSLESLQTAMTEAKKNELLPFHRPRPHIVRGRGCNESFRAAIDKSYDGPPEDDDDEGSEQSSGRDTPASGSSRQGAGDNEENKKDKKKKAKSKKKEKMKSKGKEKEKKKSEEIGDELDKKTKKKGFGLLRFGKKKEEKSKPETKVNALKQTAEILSEEELERMKEERERIEAKHQELRERQGRDRFSPPDLEDDDLDPNYARINNFKERGSPSQPLYGNRSPSPQRPLAAVSHSREPSTEDPLDGLYAKVNKQRSPPPPAADSMDRIQQLRREYLQARREGTAPAYDELEARRRGAEHDPHRMPMRNPDPRLAPRYEDVERQYASLPRRAPADPNEYPVQQWSAHREPAQYPNPQSGYHPGYPPPPREAYPRPLDPRQGDAGFYHPLPQQRGPLRQDVPPSPTIPIRGPRFDTMSRGGYRNTSPERYAYGDQRHSDPRQKSPMTAAV", "length": 1114, "header": "tr|A0AC58GFZ5-1|A0AC58GFZ5_DANRE Computationally mapped isoform of Partitioning defective 3 homolog B isoform X4 OS=Danio rerio OX=7955 GN=pard3bb PE=3 SV=1 CANONICAL=A0A8N7UUX7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1128, "start_aa": "Thr", "end_pos": 1128, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1128", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:562146", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562146", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M6YYR6-1", "protein_name": "Par-3 family cell polarity regulator beta a isoform X1", "gene_name": "pard3ba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKVTVIFGETRVVVPCKDSWMVRDLIDQATQRYKKIVEQDGEFLVRTLHVEYVDGGILDPDDMLSDLVEDKEKLTAVFEKLELQQRALVSPGGSFASGRSSPDHSEPELNILHPYLSSEIEVTPSALKSTTPLSVRSSSDPALAPPLDAISLDSEDSSRPQSTGVAPPVTVKGGAMDKLKVDNLISRNGQDTLRSLTRTVEISGDHGPLGIKVIPYCSSLSGRTLGLNIRAIEKNSRSEREKIFEEDECIVQINDAELIDKSFAQSQEVFRQAMSSSSTSTVHLEVLPVANKLRYEKSLIGQLFNSTETNPAVPKIKSPFLVRKLTPSNTATPSPEPAASQTPPIKEEELQRARHTPVELNHQSSTPSPPVSTSPTLRDHSESPALASVVHMVTKKAGKRMRIDLKKGTEGLGFTVVTRDSSLHGPGPIMVKSILPRGAAVKDGRLKSGDRILEVNGVDITGRTQEELVAMLRSTKLGETVSLIVGRQEEFLPRELKGEVSGPLVSEDGREQLMFEVPLNDSGSAGLGVSLKGNKSRETGEDLGIFIKSIIHGGAANKDGRLRVNDQLIAVNSESLVGRSNHDAMETLRHSMSTEGNLRGTIQLVVLRSLERSPAQENYEASQSANRNDSPVLRRHHHHPNSNTTNNSVPQSTVNESAPAPYRPHGGRPELLEVDYGEDDFPPPPSDLDLLETNPPHKHQPNRPEMEPFSQVSHPTNQQYPQRQKAPEYSTNKTSKSMDLVADESNMASIQGQRPEPISSNGTALGPRLGLRKSSSLESLQTAMEEVSKDEVPFHRPRAHMVRGRGCNMSFRYAIDKSYEGPSEAEDDDSEEDSGRDTPASSSSRQELDNDRKVKKKKTKKKKEKKTKKKDEAEDPDKKTKKKGFGLLSMETSPDLRSVQKNMFGRKNKEDKTKSKAKQMVAVSEEEVDKSEPELFLSKSERNSPAPERVIFPDVEDDDLDPNYARINNFRNPPASSQSPLPPGAPTNNYAQPAVPAPSREPPNEDALEGLYAKVNKQRTAPPKTESNEERLQQIRNQLQQIRPAPSYEDLTARRRPEYDPSRIRGPDSRTAPRYNDADRLYTSVPRKKPVDEYPNQNWSNQRDPVLYPNPIYDNPPRSPRLPVPKPTETPGAHYPSSPAKQMMRQDVPPSSNPGAREPPRYEALNQGNYRTASPDRYSPYTDEQYQDPRRKNPMIGAV", "length": 1199 }, "evidence": [ { "id": "RGD:1584992", "url": "https://alliancegenome.org/gene/RGD:1584992#orthology", "database": "AGR" }, { "id": "HGNC:14446", "url": "https://alliancegenome.org/gene/HGNC:14446#orthology", "database": "AGR" }, { "id": "MGI:1919301", "url": "https://alliancegenome.org/gene/MGI:1919301#orthology", "database": "AGR" }, { "id": "FB:FBgn0000163", "url": "https://alliancegenome.org/gene/FB:FBgn0000163#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A9K4-1", "protein_name": "Par-3 family cell polarity regulator alpha, b isoform 1", "gene_name": "pard3ab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKVTVCFGRTRVVVPCGDGNIKVQSLVQQAAMRYRRAIAKGEEYWVQVYRLEHGDGGILDLDDVLCDVADDKDRLVAVFDEQEPHVGGDGTSASSTGTQSPELYCGEPSTSTPLSAFQPYLPHSEIEVTTSTLRTNMPLHVRRSSDPALLNLTAMSFSEPGSQPEEPSRKNPTRWSTTAGFLKPRFATGTNSLERKGRGVDTYRSLPRDAGQWSNQKEFQREKARSSLSANHPMVDRWLERQEQDEEENGRIEPVGRADTCLEHMGVRSLDDIVKLVEVSNDGGPLGIHVVPFSGRDRRTLGLLVKRLERGGKADVQGLFQENDCIIRINNGDLRNVRFEQAQNMFRQAMRSPVILFHVVPTTMRSQYEQISHNEHNPRANIDLSGRFSPDSLTNDLDSAAHRLAQHRPQQPNNHLDTGSPVHHLVGSSGKPPTGHTSSPQRGLSPAPTTGFTKKVGRRLGIQLKKGPEGLGFSITSRDVPLGGSAPIYVKNILPRGAAIQDGRLKAGDRLLEVNGVDLNGRGQEEVVSLLRATPMGGTVTLVVLRQEETFIPREMNAEPAIQNTREWKVEEEELVLTPDGTREFLTLEVPLNDSGSAGLGVSVKGNRSKESHADLGIFVKSIINGGAACKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRKSMSTEGNKRGMIQLIVARRINKRLEGESRGSPRGLERTLSPSPDDHERRISHSLYGIEGLDDNLRPQASTNNRKMNHYQLSPTVNMPQDDTVIIEDDRPHVLPIQLSDQSSSSSHDDMGFAVETPPPPPWEPELPDSSSSANAEGQFQREGFGRQSMSEKRTKQYGDAGQLDIIKTRKSKSMDLGSSTRDVGPSLGLKKSSSLESLQTAVAEVTLNGDMPFHRPRPRIIRGRGCNESFRAAIDKSYDRPAANEDEEECMDTLEEDTEGSSRSGRDSVSTVADLTPLPVTEQQLINGNQPENDKKKEKGGKDKKKPEKEKGKTKKGMLKGLGEMFRFGKYRKDERLDGAKWKAEETHASEEETRRMKQEQERIQAKTREIRQRQARERDYAEIQDFSRSTLTSLPPEEPPYAGIGSLEHGGYHRIHTPPDSPYTQKQNGRNGHPSTSDRLTPSNHDRIQRLRQEFQQVRQEETEPDDRHRSYSMEQPWSNCSSQSSSGRHSVSVEVQLQRQEARDAFTHAQRQYSSLPRHPRKTPTPASESEWERTGPSVDAFQAAKDSGRYSSYQGPRSVPRTVPRHGCRNGFSAAPGSSSSSVGSGYNARVLLEAQELLRQEQRRREQEMKGRGPSIRVDYECQDSKGPQRQDVPPSPSQVVRLSRIHTPEKTRPFLS", "length": 1332 }, "evidence": [ { "id": "FB:FBgn0000163", "url": "https://alliancegenome.org/gene/FB:FBgn0000163#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0M2X6-1", "protein_name": "Partitioning defective 3 homolog B", "gene_name": "Pard3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVSELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILDPDDVLADVVEDKDKLIAVFDEQEPLQKIESPSGNPVDRQSPDAFDTEVAAQLAAFKPIGGEIVVTPSALKLGTPLLVRRSSDPAPGPHADAQPSTASPSGQSLKPVVLDSAQNLENRDVMNGEQTGLLMLHKTKNELSDMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFIRGIEENSRCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVVLHVLLPQNREQYEKSVIGQLNIFGNNDSASRTKAPPPTRGKAGLKAVNPTRANSPEGEESPSPQQSKSPRVPRLGRKPSSPSLSPLMGFGSKKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLVIARQEGSFLPRELKGEPDCYALSLESSEQLTLEIPLNDSGSAGLGVSLKGNKSRETGTDLGIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRLERPLEEISECGALSRPCFENCQEALSASRRNDSSLLYPCGTYSPQDKRKDLLLPSDGWAENEVPPSPPPHPSLEWGLEDFSHSSRVDSTGYFPDQHVNFRIVTPVGQPESINLKASKSMDLVPDESKVQSLADRRSDSPGKDFGPTLGLKKSSSLESLQTAVAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEAEADGLSDKSSHSGHTALNCESAPQGNPELDDVENKAKNVKKTKEKEKKKGKGKMKVKEKKQKEEHEDTERKMKRKGFGAMLRFGKKKDDKVGKTEQKGTQKSGHPGEEELERMKEERERIGAKHQELREKQARGLVDYATVATGPVHDIDDDEMDPNYARVNHFREPCTSANVFRSPSPPRAGTLGYPRDGRPLSPDHLEGLYAKVNKPYHPPALADSGRPMAGTTDRIQKLRKEYYQARREGFLLYEDEEGVTRPSDYDLHWVSGKGPDGSAHNLRFEGMERQYASLPRGGSADPVDYLTASPRGRYNERELPYYPGPHPVHSPRGSYPRPPDLRVTDLRYPQYYPPPPAHQHKGPFRQDVPPSPPQHQRVPVYQEMGRAGPRGGSPDQYPYRNQDPRQKNPMTAAV", "length": 1203 }, "evidence": [ { "id": "RGD:1584992", "url": "https://alliancegenome.org/gene/RGD:1584992#orthology", "database": "AGR" }, { "id": "HGNC:14446", "url": "https://alliancegenome.org/gene/HGNC:14446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-290", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-290#orthology", "database": "AGR" }, { "id": "MGI:1919301", "url": "https://alliancegenome.org/gene/MGI:1919301#orthology", "database": "AGR" }, { "id": "FB:FBgn0000163", "url": "https://alliancegenome.org/gene/FB:FBgn0000163#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0KHR3-1", "protein_name": "Bazooka, isoform B", "gene_name": "baz", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFDVPPKCPALANKLGGLFGWRHTYKVAAKQEGIPHGQLHKSYSLTLPKRPPSPSTYSCVKPDSWVTVTHLQTQSGILDPDDCVRDVADDREQILAHFDDPGPDPGVPQGGGDGASGSSSVGTGSPDIFRDPTNTEAPTCPRDLSTPHIEVTSTTSGPMAGLGVGLMVRRSSDPNLLASLKAEGSNKRWSAAAPHYAGGDSPERLFLDKAGGQLSPQWEEDDDPSHQLKEQLLHQQQPHAANGGSSSGNHQPFARSGRLSMQFLGDGNGYKWMEAAEKLQNQPPAQQTYQQGSHHAGHGQNGAYSSKSLPRESKRKEPLGQAYESIREKDGEMLLIINEYGSPLGLTALPDKEHGGGLLVQHVEPGSRAERGRLRRDDRILEINGIKLIGLTESQVQEQLRRALESSELRVRVLRGDRNRRQQRDSKVAEMVEVATVSPTRKPHAAPVGTSLQVANTRKLGRKIEIMLKKGPNGLGFSVTTRDNPAGGHCPIYIKNILPRGAAIEDGRLKPGDRLLEVDGTPMTGKTQTDVVAILRGMPAGATVRIVVSRQQELAEQADQPAEKSAGVAVAPSVAPPAVPAAAAPAPPIPVQKSSSARSLFTHQQQSQLNESQHFIDAGSESAASNDSLPPSSNSWHSREELTLHIPVHDTEKAGLGVSVKGKTCSNLNASGSSASSGSNGLMKHDGDLGIFVKNVIHGGAASRDGRLRMNDQLLSVNGVSLRGQNNAEAMETLRRAMVNTPGKHPGTITLLVGRKILRSASSSDILDHSNSHSHSHSNSSGGSNSNGSGNNNNSSSNASDNSGATVIYLSPEKREQRCNGGGGGGSAGNEMNRWSNPVLDRLTGGICSSNSAQPSSQQSHQQQPHPSQQQQQQRRLPAAPVCSSAALRNESYYMATNDNWSPAQMHLMTAHGNTALLIEDDAEPMSPTLPARPHDGQHCNTSSANPSQNLAVGNQGPPINTVPGTPSTSSNFDATYSSQLSLETNSGVEHFSRDALGRRSISEKHHAALDARETGTYQRNKKLREERERERRIQLTKSAVYGGSIESLTARIASANAQFSGYKHAKTASSIEQRETQQQLAAAEAEARDQLGDLGPSLGMKKSSSLESLQTMVQELQMSDEPRGHQALRAPRGRGREDSLRAAVVSEPDASKPRKTWLLEDGDHEGGFASQRNGPFQSSLNDGKHGCKSSRAKKPSILRGIGHMFRFGKNRKDGVVPVDNYAVNISPPTSVVSTATSPQLQQQQQQQLQQHQQQQQIPTAALAALERNGKPPAYQPPPPLPAPNGVGSNGIHQNDIFNHRYQHYANYEDLHQQHQQHQISGGDSTTSISETLSESTLECMRQQVIRQRIKVEAESRRHQHYHSQRSARSQDVSMHSTSSGSQPGSLAQPQAQSNGVRPMSSYYEYETVQQQRVGSIKHSHSSSATSSSSSPINVPHWKAAAMNGYSPASLNSSARSRGPFVTQVTIREQSSGGIPAHLLQQHQQQQLQQQQPTYQTVQKMSGPSQYGSAAGSQPHASKV", "length": 1520 }, "evidence": [ { "id": "RGD:1584992", "url": "https://alliancegenome.org/gene/RGD:1584992#orthology", "database": "AGR" }, { "id": "HGNC:14446", "url": "https://alliancegenome.org/gene/HGNC:14446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-290", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-290#orthology", "database": "AGR" }, { "id": "MGI:1919301", "url": "https://alliancegenome.org/gene/MGI:1919301#orthology", "database": "AGR" }, { "id": "FB:FBgn0000163", "url": "https://alliancegenome.org/gene/FB:FBgn0000163#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8TEW0-1", "protein_name": "Partitioning defective 3 homolog", "gene_name": "PARD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVTVCFGRTRVVVPCGDGHMKVFSLIQQAVTRYRKAIAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALIGLSTSVSDSNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDTSNWSNQFQRDNARSSLSASHPMVGKWLEKQEQDEDGTEEDNSRVEPVGHADTGLEHIPNFSLDDMVKLVEVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEHENLFRENDCIVRINDGDLRNRRFEQAQHMFRQAMRTPIIWFHVVPAANKEQYEQLSQSEKNNYYSSRFSPDSQYIDNRSVNSAGLHTVQRAPRLNHPPEQIDSHSRLPHSAHPSGKPPSAPASAPQNVFSTTVSSGYNTKKIGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLVGKSQEEVVSLLRSTKMEGTVSLLVFRQEDAFHPRELNAEPSQMQIPKETKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKTNQDAMETLRRSMSTEGNKRGMIQLIVARRISKCNELKSPGSPPGPELPIETALDDRERRISHSLYSGIEGLDESPSRNAALSRIMGESGKYQLSPTVNMPQDDTVIIEDDRLPVLPPHLSDQSSSSSHDDVGFVTADAGTWAKAAISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLGIADETKLNTVDDQKAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGDIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPAVDDDDEGMETLEEDTEESSRSGRESVSTASDQPSHSLERQMNGNQEKGDKTDRKKDKTGKEKKKDRDKEKDKMKAKKGMLKGLGDMFRFGKHRKDDKIEKTGKIKIQESFTSEEERIRMKQEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELMYGGVSSYEGSMALNARPQSPREGHMMDALYAQVKKPRNSKPSPVDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQPWPNARPATQSGRHSVSVEVQMQRQRQEERESSQQAQRQYSSLPRQSRKNASSVSQDSWEQNYSPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQMKKQPPSEGPSNYDSYKKVQDPSYAPPKGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS", "length": 1356 }, "evidence": [ { "id": "FB:FBgn0000163", "url": "https://alliancegenome.org/gene/FB:FBgn0000163#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8TEW8-1", "protein_name": "Partitioning defective 3 homolog B", "gene_name": "PARD3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKEGQLRVGELTQQALQRYLKTREKGPGYWVKIHHLEYTDGGILDPDDVLADVVEDKDKLIAVFEEQEPLHKIESPSGNPADRQSPDAFETEVAAQLAAFKPIGGEIEVTPSALKLGTPLLVRRSSDPVPGPPADTQPSASHPGGQSLKLVVPDSTQNLEDREVLNGVQTELLTSPRTKDTLSDMTRTVEISGEGGPLGIHVVPFFSSLSGRILGLFIRGIEDNSRSKREGLFHENECIVKINNVDLVDKTFAQAQDVFRQAMKSPSVLLHVLPPQNREQYEKSVIGSLNIFGNNDGVLKTKVPPPVHGKSGLKTANLTGTDSPETDASASLQQNKSPRVPRLGGKPSSPSLSPLMGFGSNKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAIKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETASLVIARQEGHFLPRELKGEPDCCALSLETSEQLTFEIPLNDSGSAGLGVSLKGNKSRETGTDLGIFIKSIIHGGAAFKDGRLRMNDQLIAVNGESLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRPERPMEDPAECGAFSKPCFENCQNAVTTSRRNDNSILHPLGTCSPQDKQKGLLLPNDGWAESEVPPSPTPHSALGLGLEDYSHSSGVDSAVYFPDQHINFRSVTPARQPESINLKASKSMDLVPDESKVHSLAGQKSESPSKDFGPTLGLKKSSSLESLQTAVAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEIEADGLSDKSSHSGQGALNCESAPQGNSELEDMENKARKVKKTKEKEKKKEKGKLKVKEKKRKEENEDPERKIKKKGFGAMLRFGKKKEDKGGKAEQKGTLKHGGLREEELEKMKEERERIGAKHQELREKQARGLLDYATGAIGSVYDMDDDEMDPNYARVNHFREPCTSANVFRSPSPPRAGPFGYPRDGHPLSPERDHLEGLYAKVNKPYHPLVPADSGRPTGGSTDRIQKLRKEYYQARREGFPLYEDDEGRARPSEYDLLWVPGRGPDGNAHNLRFEGMERQYASLPRGGPADPVDYLPAAPRGLYKERELPYYPGAHPMHPPKGSYPRPTELRVADLRYPQHYPPPPAPQHKGPFRQDVPPSPPQHQRMPAYQETGRPGPRGGSPDQYPYRTQDSRQKNPMTAAV", "length": 1205 }, "evidence": [ { "id": "RGD:1584992", "url": "https://alliancegenome.org/gene/RGD:1584992#orthology", "database": "AGR" }, { "id": "HGNC:14446", "url": "https://alliancegenome.org/gene/HGNC:14446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-290", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-290#orthology", "database": "AGR" }, { "id": "MGI:1919301", "url": "https://alliancegenome.org/gene/MGI:1919301#orthology", "database": "AGR" }, { "id": "FB:FBgn0000163", "url": "https://alliancegenome.org/gene/FB:FBgn0000163#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99NH2-1", "protein_name": "Partitioning defective 3 homolog", "gene_name": "Pard3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKVTVCFGRTRVVVPCGDGRMKVFSLIQQAVTRYRKAVAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASFTGTQSPEIFGSELGTNNVSAFQPYQATSEIEVTPSVLRANMPLHVRRSSDPALTGLSTSVSDNNFSSEEPSRKNPTRWSTTAGFLKQNTAGSPKTCDRKKDENYRSLPRDPSSWSNQFQRDNARSSLSASHPMVDRWLEKQEQDEEGTEEDSSRVEPVGHADTGLENMPNFSLDDMVKLVQVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEQENLFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARVIWFHVVPAANKEQYEQLSQREKNNYSPGRFSPDSHCVANRSVANNAPQALPRAPRLSQPPEQLDAHPRLPHSAHASTKPPAAPALAPPSVLSTNVGSVYNTKKVGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQEEAFHPREMNAEPSQMQTPKETKAEDEDVVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKANQEAMETLRRSMSTEGNKRGMIQLIVARRISRCNELRSPGSPAAPELPIETELDDRERRISHSLYSGIEGLDESPTRNAALSRIMGKCQLSPTVNMPHDDTVMIEDDRLPVLPPHLSDQSSSSSHDDVGFIMTEAGTWAKATISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSDASQLDFVKTRKSKSMDLVADETKLNTVDDQRAGSPSRDVGPSLGLKKSSSLESLQTAVAEVTLNGNIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPMVDDDDEGMETLEEDTEESSRSGRESVSTSSDQPSYSLERQMNGDPEKRDKTERKKDKAGKDKKKDREKEKDKLKAKKGMLKGLGDMFRFGKHRKDDKMEKMGRIKIQDSFTSEEDRVRMKEEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELLYGGMSSYEGCLALNARPQSPREGHLMDTLYAQVKKPRSSKPGDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQSWSSSRPASQSGRHSVSVEVQVQRQRQEERESFQQAQRQYSSLPRQSRKNASSISQDSWEQNYAPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQLKKQPPADGVRGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS", "length": 1333 }, "evidence": [ { "id": "FB:FBgn0000163", "url": "https://alliancegenome.org/gene/FB:FBgn0000163#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CSB4-1", "protein_name": "Partitioning defective 3 homolog B", "gene_name": "Pard3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKVTVCFGRTGIVVPCKDGQLRVRELTQQALQRYLKTRDQDPGYWVKIHHLEYTDGGILDPDDVLADVVEDKDKLIAVFDEQEPLQKTESPGGNPADRQSPDAFETEVAAQLAAFKPVGGEIVVTPSALKLGTPLLVRRSSDPAPGPHADAQPSTASLSGQSLKPVVLDSTQNVENKEAMNGEQAGLLSLHRPKDELSDMTRAVEISGEGDPLGIHVVPFFSSLSGRILGLFIRGIEENSRCKQEGLFQENECIVKINNVELLDKTFAQAQDVFRQAMKSPSVILHVLLPQNREQYEKSVIGPLNIFGNNDGASRTKAAPPARGKPGLKAVHLTRASSPEGEEPASPQQSKSPRVPRLGRKPSSPSLSPLMGFGSKKNAKKIKIDLKKGPEGLGFTVVTRDSSIHGPGPIFVKNILPKGAAVKDGRLQSGDRILEVNGRDVTGRTQEELVAMLRSTKQGETVSLVIARQEGSFLPRELKGEPDCYALSLESSEQLTLEIPLNDSGSAGLGVSLKGNKSRETGTDLGIFIKSIIHGGAAFKDGRLRMNDQLIAVNGETLLGKSNHEAMETLRRSMSMEGNIRGMIQLVILRRPERPLEELSECGALSRPGFENCQEALSTSRRNDSSILYPFGTYSPQDKRKDLLLPSDGWAENEVPPSPPPHPALEWGLEDFSHSSGVDSTGYFPDQHVNFRTVTPVRQPELINLKASKSMDLVPDEGKVQSLADRRSDSPGKDFGPTLGLKKSSSLESLQTAVAEVRKNDLPFHRPRPHMVRGRGCNESFRAAIDKSYDGPEEADADGLSDKSSRSGHTALNCESAPQGNPELDNVENKAKNIKKTKEKEKKKGKGKLKVKEKKLKEEHEDAERKMKRKGFGAMLRFGKKKDDKVGKAEQKGAQKSGHPEEEELERMKEERERIGAKHQELREKQARGLVDYATAVTGPVHDMDDDEMDPNYARVNHFREPCASANVFRSPSPLRAGPLAYPRDGRPLSPDHLEGLYAKVNKPYHPPALADSGRPMAGTTDRIQKLRKEYYQARREGFLLYEDENTRARPSDHDLRWVSGKGPDGSTHNLRFEGMERQYASLPRGGSADPVDYLTASPRGRYNDRELPYYPGPHPVHAPRGSYPRPPDLRATDLRYPQYYPPPPAHQHKGPFRQDVPPSPPQHQRVPVYQEMGRAGPRGSSPDQYPYRNQDPRQKNPMTAAV", "length": 1203 }, "evidence": [ { "id": "RGD:1584992", "url": "https://alliancegenome.org/gene/RGD:1584992#orthology", "database": "AGR" }, { "id": "HGNC:14446", "url": "https://alliancegenome.org/gene/HGNC:14446#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-290", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-290#orthology", "database": "AGR" }, { "id": "MGI:1919301", "url": "https://alliancegenome.org/gene/MGI:1919301#orthology", "database": "AGR" }, { "id": "FB:FBgn0000163", "url": "https://alliancegenome.org/gene/FB:FBgn0000163#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Z340-1", "protein_name": "Partitioning defective 3 homolog", "gene_name": "Pard3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKVTVCFGRTRVVVPCGDGRMKVFSLIQQAVTRYRKAVAKDPNYWIQVHRLEHGDGGILDLDDILCDVADDKDRLVAVFDEQDPHHGGDGTSASSTGTQSPEIFGSELGTNNVSAFRPYQTTSEIEVTPSVLRANMPLHVRRSSDPALTGLSTSVSDNNFSSEEPSRKNPTRWSTTAGFLKQNTTGSPKTCDRKKDENYRSLPRDPSSWSNQFQRDNARSSLSASHPMVDRWLEKQEQDEEGTEEDSSRVEPVGHADTGLENMPNFSLDDMVKLVQVPNDGGPLGIHVVPFSARGGRTLGLLVKRLEKGGKAEQENLFHENDCIVRINDGDLRNRRFEQAQHMFRQAMRARVIWFHVVPAANKEQYEQLSQREMNNYSPGRFSPDSHCVANRSVANNAPQALPRAPRLSQPPEQLDAHPRLPHSAHASTKPPTAPALAPPNVLSTSVGSVYNTKRVGKRLNIQLKKGTEGLGFSITSRDVTIGGSAPIYVKNILPRGAAIQDGRLKAGDRLIEVNGVDLAGKSQEEVVSLLRSTKMEGTVSLLVFRQEEAFHPREMNAEPSQMQSPKETKAEDEDIVLTPDGTREFLTFEVPLNDSGSAGLGVSVKGNRSKENHADLGIFVKSIINGGAASKDGRLRVNDQLIAVNGESLLGKANQEAMETLRRSMSTEGNKRGMIQLIVARRISRCNELRSPGSPAAPELPIETELDDRERRISHSLYSGIEGLDESPTRNAALSRIMGESGKCQLSPTVNMPHDDTVMIEDDRLPVLPPHLSDQSSSSSHDDVGFIMTEAGTWAKATISDSADCSLSPDVDPVLAFQREGFGRQSMSEKRTKQFSNASQLDFVKTRKSKSMDLGIADETKLNTVDDQRAGSPNRDVGPSLGLKKSSSLESLQTAVAEVTLNGNIPFHRPRPRIIRGRGCNESFRAAIDKSYDKPMVDDDDEGMETLEEDTEESSRSGRESVSTSSDQPSYSLERQMNGDPEKRDKAEKKKDKAGKDKKKDREKEKDKLKAKKGMLKGLGDMFRFGKHRKDDKMEKMGRIKIQDSFTSEEDRVRMKEEQERIQAKTREFRERQARERDYAEIQDFHRTFGCDDELLYGGMSSYDGCLALNARPQSPREGHLMDTLYAQVKKPRSSKPGDSNRSTPSNHDRIQRLRQEFQQAKQDEDVEDRRRTYSFEQSWSSSRPASQSGRHSVSVEVQVQRQRQEERESFQQAQRQYSSLPRQSRKNASSVSQDSWEQNYAPGEGFQSAKENPRYSSYQGSRNGYLGGHGFNARVMLETQELLRQEQRRKEQQLKKQPPADGVRGPFRQDVPPSPSQVARLNRLQTPEKGRPFYS", "length": 1337 }, "evidence": [ { "id": "FB:FBgn0000163", "url": "https://alliancegenome.org/gene/FB:FBgn0000163#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 6, "go_terms": [ { "name": "bicellular tight junction", "id": "GO:0005923", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005923", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" }, { "name": "adherens junction", "id": "GO:0005912", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005912", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" }, { "name": "cell cortex", "id": "GO:0005938", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005938", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" }, { "name": "apical junction complex", "id": "GO:0043296", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043296", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 6, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" }, { "name": "cell adhesion", "id": "GO:0007155", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007155", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" }, { "name": "intracellular protein localization", "id": "GO:0008104", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008104", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" }, { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" }, { "name": "establishment or maintenance of epithelial cell apical/basal polarity", "id": "GO:0045197", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045197", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidylinositol binding", "id": "GO:0035091", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035091", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1146, "end_pos": 1148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 516, "end_pos": 518, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" }, { "start_pos": 648, "end_pos": 650, "annotation": "n_glycosylation_sequon" }, { "start_pos": 759, "end_pos": 761, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" }, { "start_pos": 943, "end_pos": 945, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UUX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX7" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 383, "end_pos": 456, "start_aa": "Arg", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1128 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1146, "end_pos": 1148 }, { "start_pos": 178, "end_pos": 180 }, { "start_pos": 186, "end_pos": 188 }, { "start_pos": 245, "end_pos": 247 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 502, "end_pos": 504 }, { "start_pos": 516, "end_pos": 518 }, { "start_pos": 607, "end_pos": 609 }, { "start_pos": 648, "end_pos": 650 }, { "start_pos": 759, "end_pos": 761 }, { "start_pos": 93, "end_pos": 95 }, { "start_pos": 943, "end_pos": 945 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A5WVR3-1", "uniprot_ac": "A5WVR3", "uniprot_id": "A5WVR3_DANRE", "mass": { "chemical_mass": 77887.0, "monoisotopic_mass": 77887.0 }, "refseq": { "ac": "NP_001093570", "name": "translin-associated factor X-interacting protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093570" }, "gene_names": [ { "name": "tsnaxip1", "type": "recommended", "evidence": [ { "id": "A5WVR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVR3" } ] }, { "name": "tsnaxip1", "type": "synonym", "evidence": [ { "id": "NP_001093570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093570" } ] }, { "name": "wu:fc26b06", "type": "synonym", "evidence": [ { "id": "NP_001093570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093570" }, { "id": "A5WVR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVR3" } ] }, { "name": "zgc:162756", "type": "synonym", "evidence": [ { "id": "NP_001093570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093570" }, { "id": "A5WVR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVR3" } ] } ], "protein_names": [ { "name": "Translin-associated factor X-interacting protein 1", "type": "synonym", "evidence": [ { "id": "A5WVR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVR3/entry#names_and_taxonomy" } ] }, { "name": "translin-associated factor X-interacting protein 1", "type": "synonym", "evidence": [ { "id": "NP_001093570", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093570" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01042115.1, SRR26395014.604337.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On or before Nov 13, 2008 this sequence version replaced NP_001076316.1, NP_001038558.1, XP_001341863.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001093570", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093570" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WVR3", "url": "https://www.uniprot.org/uniprotkb/A5WVR3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tsnaxip1", "url": "https://www.uniprot.org/uniprotkb/A5WVR3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070424-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-39", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000030512", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000030512", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "565917", "url": "https://www.ncbi.nlm.nih.gov/gene/565917", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032755", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032755", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565917", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565917", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EWGYNLH", "url": "https://omabrowser.org/oma/group/EWGYNLH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3B2V9", "url": "https://www.orthodb.org/?gene=A0A8M3B2V9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A5WVR3", "url": "https://www.orthodb.org/?gene=A5WVR3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16306", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16306", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16306:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16306:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15739", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15739", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001093570", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093570", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3B2V9", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B2V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B2V9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B2V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TBX6", "url": "https://www.uniprot.org/uniprotkb/A0AB32TBX6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TBX6-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TBX6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TDG4", "url": "https://www.uniprot.org/uniprotkb/A0AB32TDG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TDG4-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TDG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HTV2", "url": "https://www.uniprot.org/uniprotkb/A0AC58HTV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HTV2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HTV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HTV4", "url": "https://www.uniprot.org/uniprotkb/A0AC58HTV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HTV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HTV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HTV7", "url": "https://www.uniprot.org/uniprotkb/A0AC58HTV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HTV7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HTV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HTV9", "url": "https://www.uniprot.org/uniprotkb/A0AC58HTV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HTV9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HTV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WVR3", "url": "https://www.uniprot.org/uniprotkb/A5WVR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WVR3-1", "url": "https://www.uniprot.org/uniprotkb/A5WVR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070424-39", "url": "https://zfin.org/ZDB-GENE-070424-39", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAVKDLQLPPLLHSRSSSQFESNDDNNRGLQRHIANKMSRAKLIKQTKEKEKSYFSSEPAEVTFQKPRQIRNYGSLAKPRFLEQLECLLKRELEVLDNTQDSKVQELRLQVYQEVFGHLIEEFKTYKPILSAIKKEYDITLAHLRDQIRDLLPLRPKLVLVSEQCDKKILEMRVQEREEVRALKQECRHLQSVIESMRSQQSALQIQVDHLKEDLATQYQLYRDERDARKLLITRISTMQSTQDAEHDDNNEEDESEDPVVVKMALQVCREDLTKAQIELNRLQAEYSDVVPRRDWDNLNHLHEETLMKLETLQTDFNQVKSEYDTLLEVHQKSAPTTQQHGSDSQHIATTPRPNWEQCSDILGGTERCKELFEGQSSQKRLEILMKEINSQNQFFTGLGTSSDVPIYLRYEGKLKNLKLKKADVIKVIKEIWRNKMADNEKNDDPRDLQTFLHSYLVEQYKDKAGEWAYSLMESVQNNLKDDLICLFNDVLTGKVDESIYHGQTQLLSHLLKVLIQSDITQCGSLTVSEFSEALRKAFPLKSDQDIEELLAAAQTELESSGVRISYQTLYTEDTDGQHKEFLSLVKKQATAERLQYISELRAQLEGKGEVDAEQLWVAFKTIDPSLEPENLEWNLSVAFQTKESELQAQALEKEVVLQRLSVAHVKRAGPKG", "length": 673, "header": "tr|A5WVR3-1|A5WVR3_DANRE Isoform 1 of Translin-associated factor X-interacting protein 1 OS=Danio rerio OX=7955 GN=tsnaxip1 PE=4 SV=1 CANONICAL=A5WVR3-1" }, "isoforms": [ { "isoform_ac": "A0A8M3B2V9-1", "url": "https://www.uniprot.org/uniprotkb/A5WVR3/entry#A0A8M3B2V9-1", "sequence": { "sequence": "MAVKDLQLPPLLHSRSSSQFESNDDNNRGLQRHIANKMSRAKLIKTKEKEKSYFSSEPAEVTFQKPRQIRNYGSLAKPRFLEQLECLLKRELEVLDNTQDSKVQELRLQVYQEVFGHLIEEFKTYKPILSAIKKEYDITLAHLRDQIRDLLPLRPKLVLVSEQCDKKILEMRVQEREEVRALKQECRHLQSVIESMRSQQSALQIQVDHLKEDLATQYQLYRDERDARKLLITRISTMQSTQDAEHDDNNEEDESEDPVVVKMALQVCREDLTKAQIELNRLQAEYSDVVPRRDWDNLNHLHEETLMKLETLQTDFNQVKSEYDTLLEVHQKSAPTTQQHGSDSQHIATTPRPNWEQCSDILGGTERCKELFEGQSSQKRLEILMKEINSQNQFFTGLGTSSDVPIYLRYEGKLKNLKLKKADVIKVIKEIWRNKMADNEKNDDPRDLQTFLHSYLVEQYKDKAGEWAYSLMESVQNNLKDDLICLFNDVLTGKVDESIYHGQTQLLSHLLKVLIQSDITQCGSLTVSEFSEALRKAFPLKSDQDIEELLAAAQTELESSGVRISYQTLYTEDTDGQHKEFLSLVKKQATAERLQYISELRAQLEGKGEVDAEQLWVAFKTIDPSLEPENLEWNLSVAFQTKESELQAQALEKEVVLQRLSVAHVKRAGPKG", "length": 672, "header": "tr|A0A8M3B2V9-1|A5WVR3_DANRE Computationally mapped isoform of Translin-associated factor X-interacting protein 1 OS=Danio rerio OX=7955 GN=tsnaxip1 PE=4 SV=1 CANONICAL=A5WVR3-1" }, "locus": {} }, { "isoform_ac": "A0AB32TBX6-1", "url": "https://www.uniprot.org/uniprotkb/A5WVR3/entry#A0AB32TBX6-1", "sequence": { "sequence": "MAVKDLQLPPLLHSRSLAKPRFLEQLECLLKRELEVLDNTQDSKVQELRLQVYQEVFGHLIEEFKTYKPILSAIKKEYDITLAHLRDQIRDLLPLRPKLVLVSEQCDKKILEMRVQEREEVRALKQECRHLQSVIESMRSQQSALQIQVDHLKEDLATQYQLYRDERDARKLLITRISTMQSTQDAEHDDNNEEDESEDPVVVKMALQVCREDLTKAQIELNRLQAEYSDVVPRRDWDNLNHLHEETLMKLETLQTDFNQVKSEYDTLLEVHQKSAPTTQQHGSDSQHIATTPRPNWEQCSDILGGTERCKELFEGQSSQKRLEILMKEINSQNQFFTGLGTSSDVPIYLRYEGKLKNLKLKKADVIKVIKEIWRNKMADNEKNDDPRDLQTFLHSYLVEQYKDKAGEWAYSLMESVQNNLKDDLICLFNDVLTGKVDESIYHGQTQLLSHLLKVLIQSDITQCGSLTVSEFSEALRKAFPLKSDQDIEELLAAAQTELESSGVRISYQTLYTEDTDGQHKEFLSLVKKQATAERLQYISELRAQLEGKGEVDAEQLWVAFKTIDPSLEPENLEWNLSVAFQTKESELQAQALEKEVVLQRLSVAHVKRAGPKG", "length": 614, "header": "tr|A0AB32TBX6-1|A5WVR3_DANRE Computationally mapped isoform of Translin-associated factor X-interacting protein 1 OS=Danio rerio OX=7955 GN=tsnaxip1 PE=4 SV=1 CANONICAL=A5WVR3-1" }, "locus": {} }, { "isoform_ac": "A0AB32TDG4-1", "url": "https://www.uniprot.org/uniprotkb/A5WVR3/entry#A0AB32TDG4-1", "sequence": { "sequence": "MAVKDLQLPPLLHSRSSSQFESNDDNNRGLQRHIANKMSRAKLIKQTKEKEKSYFSSEPAEVTFQKPRQIRNYGSLAKPRFLEQLECLLKRELEVLDNTQDSKVQELRLQVDHLKEDLATQYQLYRDERDARKLLITRISTMQSTQDAEHDDNNEEDESEDPVVVKMALQVCREDLTKAQIELNRLQAEYSDVVPRRDWDNLNHLHEETLMKLETLQTDFNQVKSEYDTLLEVHQKSAPTTQQHGSDSQHIATTPRPNWEQCSDILGGTERCKELFEGQSSQKRLEILMKEINSQNQFFTGLGTSSDVPIYLRYEGKLKNLKLKKADVIKVIKEIWRNKMADNEKNDDPRDLQTFLHSYLVEQYKDKAGEWAYSLMESVQNNLKDDLICLFNDVLTGKVDESIYHGQTQLLSHLLKVLIQSDITQCGSLTVSEFSEALRKAFPLKSDQDIEELLAAAQTELESSGVRISYQTLYTEDTDGQHKEFLSLVKKQATAERLQYISELRAQLEGKGEVDAEQLWVAFKTIDPSLEPENLEWNLSVAFQTKESELQAQALEKEVVLQRLSVAHVKRAGPKG", "length": 576, "header": "tr|A0AB32TDG4-1|A5WVR3_DANRE Computationally mapped isoform of Translin-associated factor X-interacting protein 1 OS=Danio rerio OX=7955 GN=tsnaxip1 PE=4 SV=1 CANONICAL=A5WVR3-1" }, "locus": {} }, { "isoform_ac": "A0AC58HTV2-1", "url": "https://www.uniprot.org/uniprotkb/A5WVR3/entry#A0AC58HTV2-1", "sequence": { "sequence": "MAVKDLQLPPLLHSRSLAKPRFLEQLECLLKRELEVLDNTQDSKVQELRLQVDHLKEDLATQYQLYRDERDARKLLITRISTMQSTQDAEHDDNNEEDESEDPVVVKMALQVCREDLTKAQIELNRLQAEYSDVVPRRDWDNLNHLHEETLMKLETLQTDFNQVKSEYDTLLEVHQKSAPTTQQHGSDSQHIATTPRPNWEQCSDILGGTERCKELFEGQSSQKRLEILMKEINSQNQFFTGLGTSSDVPIYLRYEGKLKNLKLKKADVIKVIKEIWRNKMADNEKNDDPRDLQTFLHSYLVEQYKDKAGEWAYSLMESVQNNLKDDLICLFNDVLTGKVDESIYHGQTQLLSHLLKVLIQSDITQCGSLTVSEFSEALRKAFPLKSDQDIEELLAAAQTELESSGVRISYQTLYTEDTDGQHKEFLSLVKKQATAERLQYISELRAQLEGKGEVDAEQLWVAFKTIDPSLEPENLEWNLSVAFQTKESELQAQALEKEVVLQRLSVAHVKRAGPKG", "length": 517, "header": "tr|A0AC58HTV2-1|A0AC58HTV2_DANRE Computationally mapped isoform of Translin-associated factor X-interacting protein 1 isoform X5 OS=Danio rerio OX=7955 GN=tsnaxip1 PE=4 SV=1 CANONICAL=A5WVR3-1" }, "locus": {} }, { "isoform_ac": "A0AC58HTV4-1", "url": "https://www.uniprot.org/uniprotkb/A5WVR3/entry#A0AC58HTV4-1", "sequence": { "sequence": "MAVKDLQLPPLLHSRSSSQFESNDDNNRGLQRHIANKMSRAKLIKTKEKEKSYFSSEPAEVTFQKPRQIRNYGSLAKPRFLEQLECLLKRELEVLDNTQDSKVQELRLQVDHLKEDLATQYQLYRDERDARKLLITRISTMQSTQDAEHDDNNEEDESEDPVVVKMALQVCREDLTKAQIELNRLQAEYSDVVPRRDWDNLNHLHEETLMKLETLQTDFNQVKSEYDTLLEVHQKSAPTTQQHGSDSQHIATTPRPNWEQCSDILGGTERCKELFEGQSSQKRLEILMKEINSQNQFFTGLGTSSDVPIYLRYEGKLKNLKLKKADVIKVIKEIWRNKMADNEKNDDPRDLQTFLHSYLVEQYKDKAGEWAYSLMESVQNNLKDDLICLFNDVLTGKVDESIYHGQTQLLSHLLKVLIQSDITQCGSLTVSEFSEALRKAFPLKSDQDIEELLAAAQTELESSGVRISYQTLYTEDTDGQHKEFLSLVKKQATAERLQYISELRAQLEGKGEVDAEQLWVAFKTIDPSLEPENLEWNLSVAFQTKESELQAQALEKEVVLQRLSVAHVKRAGPKG", "length": 575, "header": "tr|A0AC58HTV4-1|A0AC58HTV4_DANRE Computationally mapped isoform of Translin-associated factor X-interacting protein 1 isoform X4 OS=Danio rerio OX=7955 GN=tsnaxip1 PE=4 SV=1 CANONICAL=A5WVR3-1" }, "locus": {} }, { "isoform_ac": "A0AC58HTV7-1", "url": "https://www.uniprot.org/uniprotkb/A5WVR3/entry#A0AC58HTV7-1", "sequence": { "sequence": "MQSTQDAEHDDNNEEDESEDPVVVKMALQVCREDLTKAQIELNRLQAEYSDVVPRRDWDNLNHLHEETLMKLETLQTDFNQVKSEYDTLLEVHQKSAPTTQQHGSDSQHIATTPRPNWEQCSDILGGTERCKELFEGQSSQKRLEILMKEINSQNQFFTGLGTSSDVPIYLRYEGKLKNLKLKKADVIKVIKEIWRNKMADNEKNDDPRDLQTFLHSYLVEQYKDKAGEWAYSLMESVQNNLKDDLICLFNDVLTGKVDESIYHGQTQLLSHLLKVLIQSDITQCGSLTVSEFSEALRKAFPLKSDQDIEELLAAAQTELESSGVRISYQTLYTEDTDGQHKEFLSLVKKQATAERLQYISELRAQLEGKGEVDAEQLWVAFKTIDPSLEPENLEWNLSVAFQTKESELQAQALEKEVVLQRLSVAHVKRAGPKG", "length": 435, "header": "tr|A0AC58HTV7-1|A0AC58HTV7_DANRE Computationally mapped isoform of Translin-associated factor X-interacting protein 1 isoform X7 OS=Danio rerio OX=7955 GN=tsnaxip1 PE=4 SV=1 CANONICAL=A5WVR3-1" }, "locus": {} }, { "isoform_ac": "A0AC58HTV9-1", "url": "https://www.uniprot.org/uniprotkb/A5WVR3/entry#A0AC58HTV9-1", "sequence": { "sequence": "MRVQEREEVRALKQECRHLQSVIESMRSQQSALQIQVDHLKEDLATQYQLYRDERDARKLLITRISTMQSTQDAEHDDNNEEDESEDPVVVKMALQVCREDLTKAQIELNRLQAEYSDVVPRRDWDNLNHLHEETLMKLETLQTDFNQVKSEYDTLLEVHQKSAPTTQQHGSDSQHIATTPRPNWEQCSDILGGTERCKELFEGQSSQKRLEILMKEINSQNQFFTGLGTSSDVPIYLRYEGKLKNLKLKKADVIKVIKEIWRNKMADNEKNDDPRDLQTFLHSYLVEQYKDKAGEWAYSLMESVQNNLKDDLICLFNDVLTGKVDESIYHGQTQLLSHLLKVLIQSDITQCGSLTVSEFSEALRKAFPLKSDQDIEELLAAAQTELESSGVRISYQTLYTEDTDGQHKEFLSLVKKQATAERLQYISELRAQLEGKGEVDAEQLWVAFKTIDPSLEPENLEWNLSVAFQTKESELQAQALEKEVVLQRLSVAHVKRAGPKG", "length": 502, "header": "tr|A0AC58HTV9-1|A0AC58HTV9_DANRE Computationally mapped isoform of Translin-associated factor X-interacting protein 1 isoform X6 OS=Danio rerio OX=7955 GN=tsnaxip1 PE=4 SV=1 CANONICAL=A5WVR3-1" }, "locus": {} }, { "isoform_ac": "A5WVR3-1", "url": "https://www.uniprot.org/uniprotkb/A5WVR3/entry#A5WVR3-1", "sequence": { "sequence": "MAVKDLQLPPLLHSRSSSQFESNDDNNRGLQRHIANKMSRAKLIKQTKEKEKSYFSSEPAEVTFQKPRQIRNYGSLAKPRFLEQLECLLKRELEVLDNTQDSKVQELRLQVYQEVFGHLIEEFKTYKPILSAIKKEYDITLAHLRDQIRDLLPLRPKLVLVSEQCDKKILEMRVQEREEVRALKQECRHLQSVIESMRSQQSALQIQVDHLKEDLATQYQLYRDERDARKLLITRISTMQSTQDAEHDDNNEEDESEDPVVVKMALQVCREDLTKAQIELNRLQAEYSDVVPRRDWDNLNHLHEETLMKLETLQTDFNQVKSEYDTLLEVHQKSAPTTQQHGSDSQHIATTPRPNWEQCSDILGGTERCKELFEGQSSQKRLEILMKEINSQNQFFTGLGTSSDVPIYLRYEGKLKNLKLKKADVIKVIKEIWRNKMADNEKNDDPRDLQTFLHSYLVEQYKDKAGEWAYSLMESVQNNLKDDLICLFNDVLTGKVDESIYHGQTQLLSHLLKVLIQSDITQCGSLTVSEFSEALRKAFPLKSDQDIEELLAAAQTELESSGVRISYQTLYTEDTDGQHKEFLSLVKKQATAERLQYISELRAQLEGKGEVDAEQLWVAFKTIDPSLEPENLEWNLSVAFQTKESELQAQALEKEVVLQRLSVAHVKRAGPKG", "length": 673, "header": "tr|A5WVR3-1|A5WVR3_DANRE Isoform 1 of Translin-associated factor X-interacting protein 1 OS=Danio rerio OX=7955 GN=tsnaxip1 PE=4 SV=1 CANONICAL=A5WVR3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine.", "journal": "Genome Biol.", "date": "2009", "authors": "Webb Katharine J, Norton William Hj, Tr\u00fcmbach Dietrich, Meijer Annemarie H, Ninkovic Jovica, Topp Stefanie, Heck Daniel, Marr Carsten, Wurst Wolfgang, Theis Fabian J, Spaink Herman P, Bally-Cuif Laure", "evidence": [ { "database": "UniProtKB", "id": "A5WVR3", "url": "https://www.uniprot.org/uniprotkb/A5WVR3" } ], "reference": [ { "type": "PubMed", "id": "19646228", "url": "https://glygen.org/publication/PubMed/19646228" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A5WVR3", "url": "https://www.uniprot.org/uniprotkb/A5WVR3" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:565917", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565917", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2LNB3-1", "protein_name": "Translin-associated factor X-interacting protein 1", "gene_name": "Tsnaxip1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MANPQTRYYSFSKSRTGTQSSGGTAEVKGVEKRKLSQKRRTLPFQLSMGGHLSPWPTYTSGQTILYQRKPCSEDCRNRTNSWQQHPLGTSKPRYLEQLENYLRKELLLLDLGTDSAQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQREKIRALEPLKAKIITMNEDCSERILAMRAEERYEISLLKKEKMNLLKLIDKKNEEKISLQSEVSKLRKSLAEEYLRYLTERDARKILIGDLNELRYQREDMSLAQSPGVWGEDPVKLTLALKMTRQDLTRIQMELNTMKANFGDVVPRRDFEKQEKINLDLQEQLESLKADYEEVRKEHELLLQLHMTTLKERDQFYAELQEIQRTSTPRPDWTKCEGIIAGGSERWLMLAEGKNSDQLVDVLLEEIGSGLLREKDFFPGLGLEESVPAFLRFDGPVENKKPSKKEVVNILEDAWKERLAQEQKESFQDFFTNFLERRFGSNDAIAWAYTIFENIKLFRSIEVMNQFYAVLMGKRKETVYINQRETMSHLMKEMTNIDTQNEGLITMEQFSTILKTTFPLKKEEQIQELIEAAGWSPDINNVEMFNYRTLFTEDEEGQSEPFVQKLWEQYDSEKEAYLQELKEDLGQELTDEVSLSKMRVALMNIDPSLDKQTLCTYLSQAFQLPVAELPLEDEEKQEEIVVKLETALEQLRIADTKRVGLREPEPAS", "length": 705 }, "evidence": [ { "id": "A5WVR3", "url": "https://omabrowser.org/oma/group/A5WVR3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0ZFD5-1", "protein_name": "Translin associated factor X interacting protein 1", "gene_name": "TSNAXIP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAARRAVRGGTSPESSSEITSGQTHIRSAKPTLPKKQKALSLQLSARGQWSMWPAFAAGQTVLRNHKPCSAPEERTCSNEQALLTIPKPRHLEQLESYLRKELQTLDLTKGISQELKLQPYREIFEFFIDNFKTYKPLLSAIKNEYEATLAHQKEMIRALEPLKAMVTTVSEECTQQILALQEKEKVEINTLKQEKHHLLKFIDNMKEEKCSLQTQVEHLQMSVAEEYTRYLQEYGARKLLLAKLNDMHNEQLNVKQHQAQEKAVKGEDVVKLTLALKMARQDLTKAQVKLNAMTAEYGDVVPRRRFESLEKKYSDLLQEMKTLRKDFDQLHEEYGTLLEIHRETAEERDSFFTRLQEAERSHTPRPNWAKCSEVIPGGAERWDCLAKGKSSHQLVDVLLEEIGTGVLKEMNVFRGWGKGNKVPVHLRYEGEVKNKKPTKKDVVNILKDIWKEKTALDQQTGKRSSLPEFFLSYLQKKYGDASAVEWSYTLSEYMRLCPSNHVMSSFYEILTGKVAEEQYHSQNQLISDLQKELAACDSYSSGSLPSEQFRMALREAFPLKRRDAIQELVDASMFSLDSDDDFIDYISLFKEDEEGNPEPFVAKLRSQYVSEKQEYLQELKNSLGDVTEVDADDLKAAFCRIDPEISDQTLDAYIGLAYQVRREQPDQEVVPVDTILERLCVGDVRRVGPSPRKESTTDFEGE", "length": 703 }, "evidence": [ { "id": "A5WVR3", "url": "https://omabrowser.org/oma/group/A5WVR3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZU07-1", "protein_name": "Translin-associated factor X interacting protein 1", "gene_name": "Tsnaxip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANPQTRNQSFSKLRTRTQSSGGTPEAESIEKRKLSQKRRTLPLQLSMCGHLSPWPTYTSGQTILHKRKPCSDDSRNRANSWQQQPLSISKPRYLEQLENYLRKELLLLDLSTDSAQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQREKIRSLEPLKAKIVTVNEDCSERVLAMRAEERHEISVLKKEKMNLLKLIDKKNEEKISLQCEVAKLRKSLAEEYLRYLTERDARKILIGDLNELRYQREDMSLAQSPGVWGEDPVKLTLALKMTRQDLTRTQMELNTMKANFGDVVPRRDFEMQEKTNMELQEQLESLRGDYEEVRKEHEMLLQLHMSTLKERDQFYNELQEIQRTSTPRPDWTKCESVIAGGQERWLVLAEGKNSDQLVDVLLEEIGMGLLREKDFFPGLGFGDSIPPFLRFDGPVKNKKPSKKEVVNLLKDAWKERVAEEQKESFPDFFFNFLERRFGVNEAMAWAYTIFENIKLFRSSEIMSQFYAVLMGKTLESVYINQKDTLFHLLKELINADTQNEGSITMEQFSTVLKTTFPLKKEEQIMELMEAAGWGPDSSNTDMLNYRSLFTEDEEGQSEPFVQKLWEQYNSEKEAYLEELKQELNMEPLEEVTLLKMRGTLMNIDPTMDRQTLSAYLSQAYQIPAIDVPLDDEERQGIISVTLETALDRLKMADTKRVGPREPEQAS", "length": 705 }, "evidence": [ { "id": "HGNC:18586", "url": "https://alliancegenome.org/gene/HGNC:18586#orthology", "database": "AGR" }, { "id": "MGI:1919486", "url": "https://alliancegenome.org/gene/MGI:1919486#orthology", "database": "AGR" }, { "id": "A5WVR3", "url": "https://omabrowser.org/oma/group/A5WVR3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S2K6-1", "protein_name": "Translin associated factor X interacting protein 1", "gene_name": "TSNAXIP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASSKPQCPSLATTSRIHLRPLGVTKDDSFITETKNPQKRKLSQKRKTLLSCPFSIGGHLSPWPRYISDQTILHNRKPCSDDYQKRTNSWQQPLGTTKPRYLEQLENYLRKELLLLDLGTDSAQELRLQPFREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQREKIRALEPLKAKLVIVDEDCKERILAMRAEERYEISMLKKEKMNLLKLIDKKNEEKISLQSEVSKLRKNLAEEYLHYLSERDARKILIADLNELRYQREDMSLAQSPGIWGEDPMKLTLALKMARQDLTRTQMELNTMKANFGDVVPRRDFEMQEKVLKDLQEQLDSLRDDYEEVRKEHEMLLQLHMSTLKERDQFYSELQEIQRTSTPRPDWSKCKDVVAGGRDRWQMLAEGKNSDQLVDVLLEEIGEGLLREKDFFSGLGYGESIPTFLRFDGTVENKKPTKKDVVNILKDAWKERMAEEQKERFPDFFFNFLERRFGPGDAMAWAYTIFEYIKLFQSNEVMSQFHAVLMGKRKESVYIKQKERIAQLLKEMTNADSQNEGLLTVEQLSTVLKSAFPFKTDEKIQELMEAVGWHPSSSNADLLNYHILFTEDEEGQSTPFVQKLWEQYMEEKDAYLQELKLELGLELHEDVTLARMREALMNIDPTLDKQTLNSYLSQAFQFPMTELPEEGEEKEAGIVVQLQTALEQLHMSDVRRMGPREQEPAS", "length": 712 }, "evidence": [ { "id": "A5WVR3", "url": "https://omabrowser.org/oma/group/A5WVR3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q2TAA8-1", "protein_name": "Translin-associated factor X-interacting protein 1", "gene_name": "TSNAXIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGHLSPWPTYTSGQTILQNRKPCSDDYRKRVGSCQQHPFRTAKPQYLEELENYLRKELLLLDLGTDSTQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEGMLAHQREKIRALEPLKAKLVTVNEDCNERILAMRAEEKYEISLLKKEKMNLLKLIDKKNEEKISLQSEVTKLRKNLAEEYLHYLSERDACKILIADLNELRYQREDMSLAQSPGIWGEDPVKLTLALKMTRQDLTRTQMELNNMKANFGDVVPRRDFEMQEKTNKDLQEQLDTLRASYEEVRKEHEILMQLHMSTLKERDQFFSELQEIQRTSTPRPDWTKCKDVVAGGPERWQMLAEGKNSDQLVDVLLEEIGSGLLREKDFFPGLGYGEAIPAFLRFDGLVENKKPSKKDVVNLLKDAWKERLAEEQKETFPDFFFNFLEHRFGPSDAMAWAYTIFENIKIFHSNEVMSQFYAVLMGKRSENVYVTQKETVAQLLKEMTNADSQNEGLLTMEQFNTVLKSTFPLKTEEQIQELMEAGGWHPSSSNADLLNYRSLFMEDEEGQSEPFVQKLWEQYMDEKDEYLQQLKQELGIELHEEVTLPKLRGGLMTIDPSLDKQTVNTYMSQAFQLPESEMPEEGDEKEEAVVEILQTALERLQVIDIRRVGPREPEPAS", "length": 658 }, "evidence": [ { "id": "HGNC:18586", "url": "https://alliancegenome.org/gene/HGNC:18586#orthology", "database": "AGR" }, { "id": "MGI:1919486", "url": "https://alliancegenome.org/gene/MGI:1919486#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-39#orthology", "database": "AGR" }, { "id": "A5WVR3", "url": "https://omabrowser.org/oma/group/A5WVR3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99P25-1", "protein_name": "Translin-associated factor X-interacting protein 1", "gene_name": "Tsnaxip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANLQERKSFSKPRISIQASGGTPEAKGIEKRKLSQKRRTLPLQLSLGGHLSPWPTYTSGQTVLHNRKPCSDDSRNRANSCQQQSMSISKPKYLEQLENYLRKELLLLDLSTDSAQELRLQPYREIFEFFIEDFKTYKPLLSSIKNAYEVMLAHQKERIRSLEPLKAKIVTMNEDCSERVLAMRAEERYEISVLKKEKMNLLKLIDKKNEEKISLQSEVAKLRRSLAEEYLRYLTERDARKILIGDLNELRYQQEDMSLAQTPGVWGEDPVKLTLALKMTRQDLTRTQMELNTMKANSGDVVPRRDLEMQEKTNMELQEQLESLKADYEEVQKEHELLLQLHMSTLKERDQFYNELQEIQRTSTPRPDWTKCESIIAGGPERWLVLAEGKNSDQLVDVLLEEIGMGLLREKDFFPGLGFGDAIPPFLRFDGPVKNKKPSKKEVVNLLKDAWKERIAEEQKEPFPDFFFNFLERRFGVNDAMAWAYTIFENIKLFRSSEIMNQFYAVLMGKNLESVYINQKKTLSHLLKELLSVDTQNEGSITMEQFSTILKTTFPLKKEEQIQELMEAVGWGPDSSNTDMLNYRSLFNEDEEGQSEPFVQRLWEQYESDKEAYLEELKQELDLDPLEDVTLLKMRGTLMNIDPTMDKQTLSAYLSQAYQIPAIDVPLEDEEKQGIISIKVETALDRLRMADTKRVGPREPDPAS", "length": 704 }, "evidence": [ { "id": "HGNC:18586", "url": "https://alliancegenome.org/gene/HGNC:18586#orthology", "database": "AGR" }, { "id": "MGI:1919486", "url": "https://alliancegenome.org/gene/MGI:1919486#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-39#orthology", "database": "AGR" }, { "id": "A5WVR3", "url": "https://omabrowser.org/oma/group/A5WVR3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5WVR3", "url": "https://www.uniprot.org/uniprotkb/A5WVR3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 635, "end_pos": 637, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5WVR3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVR3" }, { "id": "PF15739", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15739" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Translin-associated factor X-interacting protein 1 N-terminal", "eco_id": "ECO_0000259", "start_pos": 87, "end_pos": 198, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 635, "end_pos": 637 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8N7UUL3-1", "uniprot_ac": "A0A8N7UUL3", "uniprot_id": "A0A8N7UUL3_DANRE", "mass": { "chemical_mass": 186920.0, "monoisotopic_mass": 186920.0 }, "refseq": { "ac": "XP_683226", "name": "deleted in lung and esophageal cancer protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683226" }, "gene_names": [ { "name": "dlec1", "type": "recommended", "evidence": [ { "id": "A0A8N7UUL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3" } ] }, { "name": "dlec1", "type": "synonym", "evidence": [ { "id": "XP_683226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683226" } ] } ], "protein_names": [ { "name": "Deleted in lung and esophageal cancer protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UUL3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3/entry#names_and_taxonomy" } ] }, { "name": "deleted in lung and esophageal cancer protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_683226", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683226" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_683226.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_683226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683226" } ] } ], "disease": [ { "disease_id": "DOID:9119", "recommended_name": { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells." }, "synonyms": [ { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "AML - acute Myeloid Leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "Leukemia, Myelocytic, acute", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloblastic leukaemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloblastic leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myelogenous leukaemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myelogenous leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloid leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia", "description": "Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections." }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML - acute myeloid leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML - acute myeloid leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "ANLL", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute Nonlymphocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute Nonlymphocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute granulocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute granulocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloblastic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelogenous leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelogenous leukemias", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukaemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute nonlymphocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute nonlymphocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "hematopoeitic - acute Myleogenous leukaemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "hematopoeitic - acute Myleogenous leukemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, reduced survival in, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, myelocytic, acute", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "myeloid leukemia, acute", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "myeloid leukemia, acute, M4/M4Eo subtype, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute non lymphoblastic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute non lymphoblastic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid", "description": "" }, { "id": "MIM:601626", "resource": "MIM", "url": "https://www.omim.org/entry/601626", "name": "Leukemia, acute myelogenous", "description": "Leukemia, acute myelogenous" } ], "unlinked_id_list": [], "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dlec1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-65", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-65", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUL3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UUL3", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000075825", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000075825", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "555583", "url": "https://www.ncbi.nlm.nih.gov/gene/555583", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059041", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059041", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060480", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060480", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:555583", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555583", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LIKYTWE", "url": "https://omabrowser.org/oma/group/LIKYTWE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YWD1", "url": "https://www.orthodb.org/?gene=A0A8M6YWD1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUL3", "url": "https://www.orthodb.org/?gene=A0A8N7UUL3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E9QEP3", "url": "https://www.orthodb.org/?gene=E9QEP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46348:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46348:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22544", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22544", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23316", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23316", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_683226", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683226", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YWD1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YWD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YWD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YWD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR75", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR75-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR78", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR78-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR80", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR80-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR85", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR85-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR87", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR87-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR91", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR91-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR99", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR99-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRA5", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRA5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRA5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRA5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QEP3", "url": "https://www.uniprot.org/uniprotkb/E9QEP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QEP3-1", "url": "https://www.uniprot.org/uniprotkb/E9QEP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-65", "url": "https://zfin.org/ZDB-GENE-091204-65", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MADETEPKALTLKSSEPSINRHTPASKTTQDISHLLASIFNDLYSTEVIGKDTVSNLSKSRRRGNSYHEKYVEELQQVHSEYNRRIQNADMLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRERSLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSERSSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYDIRMDWVTYNLEAGDGKLIDLLLACGEPFPLKDADGNEVVGGLDSSVMFPSTWDDSHTPSREGTSSTFMTQSDDFVENGEECDGEDGSGASESLAPVKKLFSVFLKPHEGTLSDYPYCITPQQTVVPAGGSSTIHLSFTPLILSCSTNQRCLGYALGFMSLDSKLALVTPGKVERVRGYELQPLRLDMQANVKPAILSVQMAEDTEVLEFSAAASDTLDGASQTQESRITRTFRLKNDTDMALSFKLSTNPPFSVLLPRQSLKLISSSPAYRHTQGLSGPGDEMRLFLLQPKNIIQVKVAFHNSASLLACVNGACEESDSQLSASLLCSDDGGKTLQFQENLTIQYSNNSIQTVSLYARLALPTLHLSSATVDFGTCYVGQTTVKEIYLHNRGGSCSYWTTLTDGNEVFRVSPDSGLLKPLGDPASCRQLLQISFTPREQKEFQTIFTVQGLLGETPLVLKVSGRGSFDESFVSPITDSSQNNTE", "length": 1702, "header": "tr|A0A8N7UUL3-1|A0A8N7UUL3_DANRE Isoform 1 of Deleted in lung and esophageal cancer protein 1 isoform X1 OS=Danio rerio OX=7955 GN=dlec1 PE=4 SV=1 CANONICAL=A0A8N7UUL3-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YWD1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3/entry#A0A8M6YWD1-1", "sequence": { "sequence": "MADETEPKALTLKSSEPSINRHTPASKTTQDISHLLASIFNDLYSTEVIGKDTVSNLSKSRRRGNSYHEKYVEELQQVHSEYNRRIQNADMLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRERSLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSESSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYDIRMDWVTYNLEAGDGKLIDLLLACGEPFPLKDADGNEVVGGLDSSVMFPSTWDDSHTPSREGTSSTFMTQSDDFVENGEECDGEDGSGASESLAPVKKLFSVFLKPHEGTLSDYPYCITPQQTVVPAGGSSTIHLSFTPLILSCSTNQRCLGYALGFMSLDSKLALVTPGKVERVRGYELQPLRLDMQANVKPAILSVQMAEDTEVLEFSAAASDTLDGASQTQESRITRTFRLKNDTDMALSFKLSTNPPFSVLLPRQSLKLISSSPAYRHTQGLSGPGDEMRLFLLQPKNIIQVKVAFHNSASLLACVNGACEESDSQLSASLLCSDDGGKTLQFQENLTIQYSNNSIQTVSLYARLALPTLHLSSATVDFGTCYVGQTTVKEIYLHNRGGSCSYWTTLTDGNEVFRVSPDSGLLKPLGDPASCRQLLQISFTPREQKEFQTIFTVQGLLGETPLVLKVSGRGSFDESFVSPITDSSQNNTE", "length": 1701, "header": "tr|A0A8M6YWD1-1|A0A8N7UUL3_DANRE Computationally mapped isoform of Deleted in lung and esophageal cancer protein 1 isoform X1 OS=Danio rerio OX=7955 GN=dlec1 PE=4 SV=1 CANONICAL=A0A8N7UUL3-1" }, "locus": {} }, { "isoform_ac": "A0A8N7UUL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3/entry#A0A8N7UUL3-1", "sequence": { "sequence": "MADETEPKALTLKSSEPSINRHTPASKTTQDISHLLASIFNDLYSTEVIGKDTVSNLSKSRRRGNSYHEKYVEELQQVHSEYNRRIQNADMLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRERSLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSERSSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYDIRMDWVTYNLEAGDGKLIDLLLACGEPFPLKDADGNEVVGGLDSSVMFPSTWDDSHTPSREGTSSTFMTQSDDFVENGEECDGEDGSGASESLAPVKKLFSVFLKPHEGTLSDYPYCITPQQTVVPAGGSSTIHLSFTPLILSCSTNQRCLGYALGFMSLDSKLALVTPGKVERVRGYELQPLRLDMQANVKPAILSVQMAEDTEVLEFSAAASDTLDGASQTQESRITRTFRLKNDTDMALSFKLSTNPPFSVLLPRQSLKLISSSPAYRHTQGLSGPGDEMRLFLLQPKNIIQVKVAFHNSASLLACVNGACEESDSQLSASLLCSDDGGKTLQFQENLTIQYSNNSIQTVSLYARLALPTLHLSSATVDFGTCYVGQTTVKEIYLHNRGGSCSYWTTLTDGNEVFRVSPDSGLLKPLGDPASCRQLLQISFTPREQKEFQTIFTVQGLLGETPLVLKVSGRGSFDESFVSPITDSSQNNTE", "length": 1702, "header": "tr|A0A8N7UUL3-1|A0A8N7UUL3_DANRE Isoform 1 of Deleted in lung and esophageal cancer protein 1 isoform X1 OS=Danio rerio OX=7955 GN=dlec1 PE=4 SV=1 CANONICAL=A0A8N7UUL3-1" }, "locus": {} }, { "isoform_ac": "A0AC58IR75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3/entry#A0AC58IR75-1", "sequence": { "sequence": "MADETEPKALTLKSSEPSINRHTPASKTTQDISHLLASIFNDLYSTEVIGKDTVSNLSKSRRRGNSYHEKYVEELQQVHSEYNRRIQNADMLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRESLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSESSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYGAGNLTHRFCPY", "length": 1227, "header": "tr|A0AC58IR75-1|A0AC58IR75_DANRE Computationally mapped isoform of Deleted in lung and esophageal cancer protein 1 isoform X11 OS=Danio rerio OX=7955 GN=dlec1 PE=4 SV=1 CANONICAL=A0A8N7UUL3-1" }, "locus": {} }, { "isoform_ac": "A0AC58IR78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3/entry#A0AC58IR78-1", "sequence": { "sequence": "MADETEPKALTLKSSEPSINRHTPASKTTQDISHLLASIFNDLYSTEVIGKDTVSNLSKSRRRGNSYHEKYVEELQQVHSEYNRRIQNADMLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRESLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSERSSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYGAGNLTHRFCPY", "length": 1228, "header": "tr|A0AC58IR78-1|A0AC58IR78_DANRE Computationally mapped isoform of Deleted in lung and esophageal cancer protein 1 isoform X10 OS=Danio rerio OX=7955 GN=dlec1 PE=4 SV=1 CANONICAL=A0A8N7UUL3-1" }, "locus": {} }, { "isoform_ac": "A0AC58IR80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3/entry#A0AC58IR80-1", "sequence": { "sequence": "MADETEPKALTLKSSEPSINRHTPASKTTQDISHLLASIFNDLYSTEVIGKDTVSNLSKSRRRGNSYHEKYVEELQQVHSEYNRRIQNADMLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRERSLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSESSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYGAGNLTHRFCPY", "length": 1228, "header": "tr|A0AC58IR80-1|A0AC58IR80_DANRE Computationally mapped isoform of Deleted in lung and esophageal cancer protein 1 isoform X9 OS=Danio rerio OX=7955 GN=dlec1 PE=4 SV=1 CANONICAL=A0A8N7UUL3-1" }, "locus": {} }, { "isoform_ac": "A0AC58IR85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3/entry#A0AC58IR85-1", "sequence": { "sequence": "MADETEPKALTLKSSEPSINRHTPASKTTQDISHLLASIFNDLYSTEVIGKDTVSNLSKSRRRGNSYHEKYVEELQQVHSEYNRRIQNADMLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRERSLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSERSSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYGAGNLTHRFCPY", "length": 1229, "header": "tr|A0AC58IR85-1|A0AC58IR85_DANRE Computationally mapped isoform of Deleted in lung and esophageal cancer protein 1 isoform X8 OS=Danio rerio OX=7955 GN=dlec1 PE=4 SV=1 CANONICAL=A0A8N7UUL3-1" }, "locus": {} }, { "isoform_ac": "A0AC58IR87-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3/entry#A0AC58IR87-1", "sequence": { "sequence": "MLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRESLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSERSSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYDIRMDWVTYNLEAGDGKLIDLLLACGEPFPLKDADGNEVVGGLDSSVMFPSTWDDSHTPSREGTSSTFMTQSDDFVENGEECDGEDGSGASESLAPVKKLFSVFLKPHEGTLSDYPYCITPQQTVVPAGGSSTIHLSFTPLILSCSTNQRCLGYALGFMSLDSKLALVTPGKVERVRGYELQPLRLDMQANVKPAILSVQMAEDTEVLEFSAAASDTLDGASQTQESRITRTFRLKNDTDMALSFKLSTNPPFSVLLPRQSLKLISSSPAYRHTQGLSGPGDEMRLFLLQPKNIIQVKVAFHNSASLLACVNGACEESDSQLSASLLCSDDGGKTLQFQENLTIQYSNNSIQTVSLYARLALPTLHLSSATVDFGTCYVGQTTVKEIYLHNRGGSCSYWTTLTDGNEVFRVSPDSGLLKPLGDPASCRQLLQISFTPREQKEFQTIFTVQGLLGETPLVLKVSGRGSFDESFVSPITDSSQNNTE", "length": 1611, "header": "tr|A0AC58IR87-1|A0AC58IR87_DANRE Computationally mapped isoform of Deleted in lung and esophageal cancer protein 1 isoform X6 OS=Danio rerio OX=7955 GN=dlec1 PE=4 SV=1 CANONICAL=A0A8N7UUL3-1" }, "locus": {} }, { "isoform_ac": "A0AC58IR91-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3/entry#A0AC58IR91-1", "sequence": { "sequence": "MLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRERSLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSESSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYDIRMDWVTYNLEAGDGKLIDLLLACGEPFPLKDADGNEVVGGLDSSVMFPSTWDDSHTPSREGTSSTFMTQSDDFVENGEECDGEDGSGASESLAPVKKLFSVFLKPHEGTLSDYPYCITPQQTVVPAGGSSTIHLSFTPLILSCSTNQRCLGYALGFMSLDSKLALVTPGKVERVRGYELQPLRLDMQANVKPAILSVQMAEDTEVLEFSAAASDTLDGASQTQESRITRTFRLKNDTDMALSFKLSTNPPFSVLLPRQSLKLISSSPAYRHTQGLSGPGDEMRLFLLQPKNIIQVKVAFHNSASLLACVNGACEESDSQLSASLLCSDDGGKTLQFQENLTIQYSNNSIQTVSLYARLALPTLHLSSATVDFGTCYVGQTTVKEIYLHNRGGSCSYWTTLTDGNEVFRVSPDSGLLKPLGDPASCRQLLQISFTPREQKEFQTIFTVQGLLGETPLVLKVSGRGSFDESFVSPITDSSQNNTE", "length": 1611, "header": "tr|A0AC58IR91-1|A0AC58IR91_DANRE Computationally mapped isoform of Deleted in lung and esophageal cancer protein 1 isoform X7 OS=Danio rerio OX=7955 GN=dlec1 PE=4 SV=1 CANONICAL=A0A8N7UUL3-1" }, "locus": {} }, { "isoform_ac": "A0AC58IR99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3/entry#A0AC58IR99-1", "sequence": { "sequence": "MADETEPKALTLKSSEPSINRHTPASKTTQDISHLLASIFNDLYSTEVIGKDTVSNLSKSRRRGNSYHEKYVEELQQVHSEYNRRIQNADMLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRESLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSESSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYDIRMDWVTYNLEAGDGKLIDLLLACGEPFPLKDADGNEVVGGLDSSVMFPSTWDDSHTPSREGTSSTFMTQSDDFVENGEECDGEDGSGASESLAPVKKLFSVFLKPHEGTLSDYPYCITPQQTVVPAGGSSTIHLSFTPLILSCSTNQRCLGYALGFMSLDSKLALVTPGKVERVRGYELQPLRLDMQANVKPAILSVQMAEDTEVLEFSAAASDTLDGASQTQESRITRTFRLKNDTDMALSFKLSTNPPFSVLLPRQSLKLISSSPAYRHTQGLSGPGDEMRLFLLQPKNIIQVKVAFHNSASLLACVNGACEESDSQLSASLLCSDDGGKTLQFQENLTIQYSNNSIQTVSLYARLALPTLHLSSATVDFGTCYVGQTTVKEIYLHNRGGSCSYWTTLTDGNEVFRVSPDSGLLKPLGDPASCRQLLQISFTPREQKEFQTIFTVQGLLGETPLVLKVSGRGSFDESFVSPITDSSQNNTE", "length": 1700, "header": "tr|A0AC58IR99-1|A0AC58IR99_DANRE Computationally mapped isoform of Deleted in lung and esophageal cancer protein 1 isoform X4 OS=Danio rerio OX=7955 GN=dlec1 PE=4 SV=1 CANONICAL=A0A8N7UUL3-1" }, "locus": {} }, { "isoform_ac": "A0AC58IRA5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3/entry#A0AC58IRA5-1", "sequence": { "sequence": "MLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRERSLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSERSSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYDIRMDWVTYNLEAGDGKLIDLLLACGEPFPLKDADGNEVVGGLDSSVMFPSTWDDSHTPSREGTSSTFMTQSDDFVENGEECDGEDGSGASESLAPVKKLFSVFLKPHEGTLSDYPYCITPQQTVVPAGGSSTIHLSFTPLILSCSTNQRCLGYALGFMSLDSKLALVTPGKVERVRGYELQPLRLDMQANVKPAILSVQMAEDTEVLEFSAAASDTLDGASQTQESRITRTFRLKNDTDMALSFKLSTNPPFSVLLPRQSLKLISSSPAYRHTQGLSGPGDEMRLFLLQPKNIIQVKVAFHNSASLLACVNGACEESDSQLSASLLCSDDGGKTLQFQENLTIQYSNNSIQTVSLYARLALPTLHLSSATVDFGTCYVGQTTVKEIYLHNRGGSCSYWTTLTDGNEVFRVSPDSGLLKPLGDPASCRQLLQISFTPREQKEFQTIFTVQGLLGETPLVLKVSGRGSFDESFVSPITDSSQNNTE", "length": 1612, "header": "tr|A0AC58IRA5-1|A0AC58IRA5_DANRE Computationally mapped isoform of Deleted in lung and esophageal cancer protein 1 isoform X5 OS=Danio rerio OX=7955 GN=dlec1 PE=4 SV=1 CANONICAL=A0A8N7UUL3-1" }, "locus": {} }, { "isoform_ac": "E9QEP3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3/entry#E9QEP3-1", "sequence": { "sequence": "MADETEPKALTLKSSEPSINRHTPASKTTQDISHLLASIFNDLYSTEVIGKDTVSNLSKSRRRGNSYHEKYVEELQQVHSEYNRRIQNADMLETHIIQARLQAAAKEEHDRNKILEEVGEAYQQLGLPPVKSAFKWCVDSGLLRSNSLICPLDYTTVHNPVVKSPKARSSPGFAKPTFSYNMHISTELQDDGYTPLPPHAHSAHSLLEYSEETITLSSSPESSSINDTELGLVAKASWMEKTSAKSHAEDRASLKKHKDRHKFLHNPRFLLPNTQHGGKSLIIPGKKKLENVGKSRKNNGRESLEGHAPIFTANPPVIFFSDYRVGQVYETSVELKNMTASSRHIRMIPPTSPHFSVGLGRFPGEGGIVAPGMSCQYMVRFAPDSLADYEDALVVETQMLYPLIIPIEACRSPPILTLPAVMDCGFCLVGGVKFMEVLCRNEGLSAGTFCVMPKKQWPASSLRSAVKSTFTEQPPFAISPSIFGLHPGQATVIEVVFFPTTPELSTQDFTIVCDNCQVKDITLQGTGQLITVELLSVSGGEDQPEFAELCDITADHYVRFNTTNPHSTLQKTLVVKNNTHLELPYHWQIMKPSLQCLLPGETPDPSSIQHLLDTDSAFSISPVIGILNPAQEHEFLLTYAPKDIKDYHSVCHLVIMDVPSPPKVCDDGTCPDTALHANNVTILEVEVKGSTEPYKILLEPYAVLIPGETYIHNTICKRFKMWNHSKSVIHFEWERVIDSHVIEVEPSSGVIEMNECFDMELYLTGRSPGHFTSTLQCHILHHPKTIGLAIEATFKGPHCSLNVPSLDFGLLQMGNERILTIEVTNNSLLDAHWSLEVLSQTQKLIDGQVHINPNKGVLAALESCSVDVAFRAMHCQVFESVLQLSVLNGTGCHVSIHAVVQSPQVCLLNCELLFADLYVGVSQTGSVTLFNQTLLPAHFTWGRLQGSQAHLCSAVFSPSAGSLGPNAKTEVSVSFTAHTVEDLTEVNGVCEVKGMENPLVLGIFSKAKPLRVSYSLLCNGINSGDGDHQPILLDFTEHEPAVIGKSVKRQLLITNNTAITAPFTVDTEYFTGDCPSQSEGNSERSSAPFHSIQAKKIQQKAYDEFVSRLLSHGRGATFYVEPKSGMLGPFESQTINITTFTNMWGDYQDNLICKVGDLNPTHIHMKMSVRGCPVYFQMIGPQPDNQNQGPVIRFGSHVSGGDTVSRSLRLINTSPYDIRMDWVTYNLEAGDGKLIDLLLACGEPFPLKDADGNEVVGGLDSSVMFPSTWDDSHTPSREGTSSTFMTQSDDFVENGEECDGEDGSGASESLAPVKKLFSVFLKPHEGTLSDYPYCITPQQTVVPAGGSSTIHLSFTPLILSCSTNQRCLGYALGFMSLDSKLALVTPGKVERVRGYELQPLRLDMQANVKPAILSVQMAEDTEVLEFSAAASDTLDGASQTQESRITRTFRLKNDTDMALSFKLSTNPPFSVLLPRQSLKLISSSPAYRHTQGLSGPGDEMRLFLLQPKNIIQVKVAFHNSASLLACVNGACEESDSQLSASLLCSDDGGKTLQFQENLTIQYSNNSIQTVSLYARLALPTLHLSSATVDFGTCYVGQTTVKEIYLHNRGGSCSYWTTLTDGNEVFRVSPDSGLLKPLGDPASCRQLLQISFTPREQKEFQTIFTVQGLLGETPLVLKVSGRGSFDESFVSPITDSSQNNTE", "length": 1701, "header": "tr|E9QEP3-1|E9QEP3_DANRE Computationally mapped isoform of Deleted in lung and esophageal cancer protein 1 isoform X2 OS=Danio rerio OX=7955 GN=dlec1 PE=4 SV=1 CANONICAL=A0A8N7UUL3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:555583", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555583", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1ADC0-1", "protein_name": "DLEC1 cilia and flagella associated protein", "gene_name": "DLEC1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAQRSPSSRSQDISHLLSSTFKDLYTGDVIGADIEANWLKSRGGDDAYHEAFTEELQKLVVEYNHRLTEADAVEENIIQAQVRAKAEEERALNVLKGDAGKDFHKMGLPPVASSFRWIVDNELLRKNHLTCPDDYITDKLPVTRAPKGKAEPGYVKETFSFKQRVSSDSRDQMSAHLQKISAHLPSVSLSTLILPSTPDSYHRTKRTSKKSSASQKADWKGSKCKAEREECAYLAKLEKRQNFLKNPRFFPPNAPHGGKSLVMSQGQVEQIISNTSAECNTGDISFVPVFLAKPPTVFFSDYEVGRVYEITVELQNITSTCHRVGVIPPSTSVFSIGPGKFPGKGGMIAPGMTCQYTVQFVPESLADYTDYIWVQTPVSEPLLIPIQAKRAPPVLTLPRIIDCGFCLVGGIKVTVILCRNVGFSTGKFCIMPQEAWPPPNFRAVATLGSVIQDPFGIYPAVFELAPGQSTRVKVVFFPSLPEVSQQTYTIVCDNCQVNDVTVTGVGQLIALELLHVTGGESSSEPDEVTDVTAQHLIRFDPQNPHTTTQKILVIRNATHVELPFYWQIIKPNLQPIVPGETAHFVTPEYNRETESVFSLSPKQGVLLPHADHDFTLTYTPQELKIYHSVIQLVLRDIPESPSLVKGRILQNIPEYTAEDVIALDIEVKGSTEPFQLLLEPYAVIIPGENFLGVKVRRTFKMWNNSKSPIKYTWENITDCTIMEVEPLTGVIDRNEHCEFELMITGIRPGCVSHNLQCQIKHSAEPVVLHVEAAFKGPLLHISIPSLRLGLIKPGETVVGTFEIQNLCQLPARWRMQESQACLAERNEEVSPFTIQPPAEEIPPLGSCSVSVQYMSLLCQRLHTVLELEVENGERSYLPVSVEVQTPQACLISSHLVLTEMYTGVPVKATSKLFNQTRLPAKYSWGNLIGSQAAFCSATVTPASGILAPNEEKEFCIELTANITGELKGVALSCSIEDMIEPLFLSISGEVKGLHVTYSVPCEGGDASDERKMLQSPRDLLLDFGSEVALKDIVKRQLILTNHTAISAPFKLEAVYFTGSSPTPEQSVSLSSDYLVKRRGPITKHAAKRAQSEFAAAMLSHGKGVAFHVQPSSGTLQAFQQLIIEITAYNNMWGEYSDDLVCKVGDLQPTLIPMQMTVKGCPIFLQMTGPQTQRPIIRFGTHVSGGCPVFRNVQLNNPTAFDIRLDWETYNQEEGDKKLVDLLMLFEDPFPPKDMAKNETASTGSNSEIVLGLDQPPVPCGSIHPSLQTTDESSNTECEEEGIITQEPTRQKIVSVLLRPHEGVPADSPYSITPRQIVVPGGGSSSVCISFTPHVLPEPVAEVRCDGFVLGFMSLDDELAKTVPDKVHRRDGYDTAPLRIDMRASVRQALLKVDTDHDGGMVFYSVASDLLPDQPLLGVLSDSVLTQSLKLTNCTKVPLYFSLLLSAPFSLTSTDLKKSTNTFHSETEETEQEPQLVLYPQQNMLVKVSFHITLKLLMYQHLPDTQMLPGFQVLQGESGERKLKFSQNLIIEYSNHSTQLVPVTAYLTVPVLELSCNMVDFKTCLVAQTKTEHVFLCNRSSCRIYWTALLDQQERHSDLEVFSVSPANGILEAREGEQPTKDMLQITFTARSDTEYETILTVTGMLGEKPCKLQIRGQGTYDEKYEDMY", "length": 1668 }, "evidence": [ { "id": "A0A8N7UUL3", "url": "https://omabrowser.org/oma/group/A0A8N7UUL3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q68FQ8-1", "protein_name": "Deleted in lung and esophageal cancer protein 1 homolog", "gene_name": "Dlec1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPESKKELQSPASSFVMSSETMWESTPRQPESTSLSWSPRKSLRSLTVFTDYCQFGYPTRSLRAGFQELPPLPEPQTLRLRPASLRTQDISHLLARVFRNLYTAQVIGDDLSDSLIKARGSEDARHEEFLDQLQQARAIYKKRLDDVAMLEKHITQARARDIAETEHATKQGRLHVVEAPVKLPPVKTVFRWCIDNELMQKHHLISTEDYYNDPLPFCPAPKRSPTPMYSKMTFSCEKRFTHKSDLERKAEEHCRKLVEFDDLEYTTDSLRSVSKTKGKTKVTIKKASTPANKKWMEHLQVPQRALDRRLLARMQNRNHYLKNPRFFPPNTPHGGKSLIVPSRKPERRGSLSAKPEWRCVCSSRRIPGNVSFRVNLDLVYGGPQTLASQGSVPEESGVLGSTSGMAFDPQGPRVRLFSAVRSRGVDPWEPVWASSGHPKWGGAGAGAYSHVTLAWYVDYLFLLL", "length": 465 }, "evidence": [ { "id": "HGNC:2899", "url": "https://alliancegenome.org/gene/HGNC:2899#orthology", "database": "AGR" }, { "id": "RGD:1561649", "url": "https://alliancegenome.org/gene/RGD:1561649#orthology", "database": "AGR" }, { "id": "MGI:2443671", "url": "https://alliancegenome.org/gene/MGI:2443671#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-65", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-65#orthology", "database": "AGR" }, { "id": "A0A8N7UUL3", "url": "https://omabrowser.org/oma/group/A0A8N7UUL3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BLA1-1", "protein_name": "Deleted in lung and esophageal cancer protein 1 homolog", "gene_name": "Dlec1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSESKEEQQCTASSAVMSSLETQFLSVPHQLESASLSWSIRKSLHSSTVLMDDCHFGFPTRSLRAGFHALPPLPEPQTLRLRPASLRTQEISHLLARVFRNLYTAQVIGDDLSDSLIKARGSEDARHEEFLDQLQQARAIYKQRLDEAAMLERHIMQARARDIAETEHTTKQSRLQVVETPVKLPPVKTAFRWCLDSKLMRKHHLISTEDYYTDPVPFCPAPKDKSTLGCSKLTFSCEQRFLRKSELDREAEEHCRQLTECDDFEYTVDSLGSISKAKERTTDSVKKTSRPKNKKWMEHLQVPQRALDRRLLASMENRNHFLKNPRFFPPNTPHGGKSLIVPLSKPERRASLNAEPEWSCTDAPVFLAKPSVGFFTDYEIGPVYEMVIALQNTTSTSRFLRVLPPSSPYFALGLGMFPGKGGIVAPGMTCQYIVQFIPDCLGDFDDFILVETQSPHTLVIPLQARRPPPVLTLSPVLDCGHCLIGGVKITKFICKNVGFSVGKFCIMPQKSWPPPSFRAVATTGFVEQPPFGVMPSVFELAPGYAILLEVLFLPTGLGQAEETFIIVCDNCQIKEVVVVGTGQLVALDLIHISGGKNEPDPGELKDLTAQYFIRFEPENVQSTPKKQLIIRNAT", "length": 635 }, "evidence": [ { "id": "HGNC:2899", "url": "https://alliancegenome.org/gene/HGNC:2899#orthology", "database": "AGR" }, { "id": "RGD:1561649", "url": "https://alliancegenome.org/gene/RGD:1561649#orthology", "database": "AGR" }, { "id": "MGI:2443671", "url": "https://alliancegenome.org/gene/MGI:2443671#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-65", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-65#orthology", "database": "AGR" }, { "id": "A0A8N7UUL3", "url": "https://omabrowser.org/oma/group/A0A8N7UUL3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y238-1", "protein_name": "Deleted in lung and esophageal cancer protein 1", "gene_name": "DLEC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METRSSKTRRSLASRTNECQGTMWAPTSPPAGSSSPSQPTWKSSLYSSLAYSEAFHYSFAARPRRLTQLALAQRPEPQLLRLRPSSLRTQDISHLLTGVFRNLYSAEVIGDEVSASLIKARGSENERHEEFVDQLQQIRELYKQRLDEFEMLERHITQAQARAIAENERVMSQAGVQDLESLVRLPPVKSVSRWCIDSELLRKHHLISPEDYYTDTVPFHSAPKGISLPGCSKLTFSCEKRSVQKKELNKKLEDSCRKKLAEFEDELDHTVDSLTWNLTPKAKERTREPLKKASQPRNKNWMNHLRVPQRELDRLLLARMESRNHFLKNPRFFPPNTRYGGKSLVFPPKKPAPIGEFQSTEPEQSCADTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGKGGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCGYCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFELAPGHAILVEVLFSPKSLGKAEQTFIIMCDNCQIKELVTIGIGQLIALDLIYISGEKSQPDPGELTDLTAQHFIRFEPENLRSTARKQLIIRNATHVELAFYWQIMKPNLQPLMPGETFSMDSIKCYPDKETAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVYAEVQKPHVYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQNSLSKKTSLPNMPPALLKTVRMQEHLAKREQLDFMESMLSHGKGAAFFPHFSQGMLGPYQQLCIDITGCANMWGEYWDNLICTVGDLLPEVIPVHMAAVGCPISSLRTTSYTIDQAQKEPAMRFGTQVSGGDTVTRTLRLNNSSPCDIRLDWETYVPEDKEDRLVELLVFYGPPFPLRDQAGNELVCPDTPEGGCLLWSPGPSSSSEFSHETDSSVEGSSSASNRVAQKLISVILQAHEGVPSGHLYCISPKQVVVPAGGSSTIYISFTPMVLSPEILHKVECTGYALGFMSLDSKVEREIPGKRHRLQDFAVGPLKLDLHSYVRPAQLSVELDYGGSMEFQCQASDLIPEQPCSGVLSELVTTHHLKLTNTTEIPHYFRLMVSRPFSVSQDGASQDHRAPGPGQKQECEEETASADKQLVLQAQENMLVNVSFSLSLELLSYQKLPADQTLPGVDIQQSASGEREMVFTQNLLLEYTNQTTQVVPLRAVVAVPELQLSTSWVDFGTCFVSQQRVREVYLMNLSGCRSYWTMLMGQQEPAKAAVAFRVSPNSGLLEARSANAPPTSIALQVFFTARSSELYESTMVVEGVLGEKSCTLRLRGQGSYDERYMLPHQP", "length": 1755 }, "evidence": [ { "id": "HGNC:2899", "url": "https://alliancegenome.org/gene/HGNC:2899#orthology", "database": "AGR" }, { "id": "RGD:1561649", "url": "https://alliancegenome.org/gene/RGD:1561649#orthology", "database": "AGR" }, { "id": "MGI:2443671", "url": "https://alliancegenome.org/gene/MGI:2443671#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-65", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-65#orthology", "database": "AGR" }, { "id": "A0A8N7UUL3", "url": "https://omabrowser.org/oma/group/A0A8N7UUL3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3" } ], "pmid": "" }, { "name": "cilium", "id": "GO:0005929", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005929", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of cell population proliferation", "id": "GO:0008285", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008285", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "tubulin binding", "id": "GO:0015631", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015631", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUL3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUL3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1056, "end_pos": 1058, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1137, "end_pos": 1139, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1213, "end_pos": 1215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1454, "end_pos": 1456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1558, "end_pos": 1560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1565, "end_pos": 1567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1699, "end_pos": 1701, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 680, "end_pos": 682, "annotation": "n_glycosylation_sequon" }, { "start_pos": 724, "end_pos": 726, "annotation": "n_glycosylation_sequon" 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annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325649.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325649" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL69", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL69" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rsbn1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL69", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-191016-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-191016-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PL69", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PL69", "database": "AlphaFoldDB", "categories": [] }, { "id": "100330644", "url": "https://www.ncbi.nlm.nih.gov/gene/100330644", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026306", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026306", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100330644", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330644", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR13354", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13354", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13354:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13354:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_021325649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325649", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PL69", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PL69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-191016-1", "url": "https://zfin.org/ZDB-GENE-191016-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRKKSLLKPFKFTCKMAAQVDLLRVKVEEKSRDSFDKATKEKKKKKKRECSPPDDKRERSEKEAKKIKLHHHQHSHQHEQQRAHPPHQQQNNQARNFSKEQALVPHRHHHHHHNHSSKKEVPPVWPPRKVTPAAGAAVAHVPQKTVQPPSPLFTFTPLKVAKAKPLNNKPKHIEKDAKLKPKKENAEANVKVGECKKKKEPHGENGKTQTLEEYLLKKKKKKKRHREDERGKKLRMHHKEVQTVCSGDTPPLSEDPVGHAYIKEEKDLGEYDAPKEAKKPFLTHQDHYIRSSWLQTNTCFSRLIHEEKQPNGGASVLHAYADELSLLRPGETEKFAQEFMKLAFAEQPKGAARYALAVVHGAAAYLPDFLDYFAFNFPNTPVKVEILGKKDIETTTIANFHTQVSRTYCCGTYRAGPMRQISLVGAVDEEVGDFFPEFLDMLEESPFLKMTLPWGSLSSLKLDCRSQSDDGPIMWVRPGEQMVPTADMPKSPFKRRRSMNEIKNLHYLPRASEPREVLFEDRTRAHADHVGQSFDWQSTAAVGVLKAVHFGEWSDQPRITKDVVCFHAEDFNDVVQRLQLDLYEPPVSQCVQWVDDAKLNQLRREGIRYVRMQLCDDDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHSEEEEEEAKDVKTKDLCTTSCPPPVHPDTKVTSCARLQTDAAQGGVAKMDELVFQRPATPPREPQPAPPHPAKSARTVYAAPCSESSPFPATSPLCSSTPEPVLPPGPAEPTSDSQLNGSRATDFPK", "length": 776, "header": "tr|A0A8M9PL69-1|A0A8M9PL69_DANRE Isoform 1 of Lysine-specific demethylase 9 OS=Danio rerio OX=7955 GN=rsbn1 PE=1 SV=3 CANONICAL=A0A8M9PL69-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PL69-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL69/entry#A0A8M9PL69-1", "sequence": { "sequence": "MRKKSLLKPFKFTCKMAAQVDLLRVKVEEKSRDSFDKATKEKKKKKKRECSPPDDKRERSEKEAKKIKLHHHQHSHQHEQQRAHPPHQQQNNQARNFSKEQALVPHRHHHHHHNHSSKKEVPPVWPPRKVTPAAGAAVAHVPQKTVQPPSPLFTFTPLKVAKAKPLNNKPKHIEKDAKLKPKKENAEANVKVGECKKKKEPHGENGKTQTLEEYLLKKKKKKKRHREDERGKKLRMHHKEVQTVCSGDTPPLSEDPVGHAYIKEEKDLGEYDAPKEAKKPFLTHQDHYIRSSWLQTNTCFSRLIHEEKQPNGGASVLHAYADELSLLRPGETEKFAQEFMKLAFAEQPKGAARYALAVVHGAAAYLPDFLDYFAFNFPNTPVKVEILGKKDIETTTIANFHTQVSRTYCCGTYRAGPMRQISLVGAVDEEVGDFFPEFLDMLEESPFLKMTLPWGSLSSLKLDCRSQSDDGPIMWVRPGEQMVPTADMPKSPFKRRRSMNEIKNLHYLPRASEPREVLFEDRTRAHADHVGQSFDWQSTAAVGVLKAVHFGEWSDQPRITKDVVCFHAEDFNDVVQRLQLDLYEPPVSQCVQWVDDAKLNQLRREGIRYVRMQLCDDDIYFIPRNVIHQFKTVSAVCSLAWHIRLKQYHSEEEEEEAKDVKTKDLCTTSCPPPVHPDTKVTSCARLQTDAAQGGVAKMDELVFQRPATPPREPQPAPPHPAKSARTVYAAPCSESSPFPATSPLCSSTPEPVLPPGPAEPTSDSQLNGSRATDFPK", "length": 776, "header": "tr|A0A8M9PL69-1|A0A8M9PL69_DANRE Isoform 1 of Lysine-specific demethylase 9 OS=Danio rerio OX=7955 GN=rsbn1 PE=1 SV=3 CANONICAL=A0A8M9PL69-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 131, "start_aa": "Thr", "end_pos": 131, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr131", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100330644", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330644", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL69", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL69" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 114, "end_pos": 116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 767, "end_pos": 769, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 131 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 114, "end_pos": 116 }, { "start_pos": 767, "end_pos": 769 }, { "start_pos": 96, "end_pos": 98 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PLJ3-1", "uniprot_ac": "A0A8M9PLJ3", "uniprot_id": "A0A8M9PLJ3_DANRE", "mass": { "chemical_mass": 28604.0, "monoisotopic_mass": 28604.0 }, "refseq": { "ac": "XP_021327898", "name": "uncharacterized protein si:dkey-27b3.4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327898" }, "gene_names": [ { "name": "si:dkey-27b3.4", "type": "recommended", "evidence": [ { "id": "A0A8M9PLJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ3" } ] }, { "name": "si:dkey-27b3.4", "type": "synonym", "evidence": [ { "id": "XP_021327898", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327898" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkey-27b3.4 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PLJ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkey-27b3.4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021327898", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327898" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021327898.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021327898", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327898" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-27b3.4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-131", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-131", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PLJ3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PLJ3", "database": "AlphaFoldDB", "categories": [] }, { "id": "103911726", "url": "https://www.ncbi.nlm.nih.gov/gene/103911726", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:103911726", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103911726", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR34488", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34488", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34488:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34488:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_021327898", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327898", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLJ3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GLD1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GLD1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GLD1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GLD1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-131", "url": "https://zfin.org/ZDB-GENE-091204-131", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKAKESYCITNALPSDPPLVLTSHSFVKEEENGQTMDCAVDDFKRMLHNKASGLKESSSVKKCDVILYFCPITSRAGTDIDAAMKHLNQITSDLQASKLAIVVVLHITFDPDKIISDSEKIIKQENTYAVDCLLCETDGLLECQKNAEAIKKTANHFKSKKLTSFYCLTKDDRNTSSPIYENTESTPLIHSDDSSEGVIQRQEDVPRHEDKLRQADKLRQDACCFCGVCFFFCCGWLCECKPYKRICACCHCQK", "length": 254, "header": "tr|A0A8M9PLJ3-1|A0A8M9PLJ3_DANRE Isoform 1 of Uncharacterized protein si:dkey-27b3.4 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-27b3.4 PE=4 SV=2 CANONICAL=A0A8M9PLJ3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLJ3-1", "url": 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si:dkey-27b3.4 isoform X2 OS=Danio rerio OX=7955 GN=si:dkey-27b3.4 PE=4 SV=1 CANONICAL=A0A8M9PLJ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103911726", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103911726", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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"https://monarchinitiative.org/disease/MONDO:0010393", "name": "mental retardation, X-linked, with macrocephaly", "description": "" }, { "id": "MIM:300659", "resource": "MIM", "url": "https://www.omim.org/entry/300659", "name": "Intellectual developmental disorder, X-linked 93", "description": "Intellectual developmental disorder, X-linked 93" } ], "unlinked_id_list": [], "evidence": [ { "id": "0112045", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112045" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQW9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQW9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "brwd3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQW9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100921-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100921-43", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00200", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00200", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05496", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05496", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05529", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05529", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "553209", "url": "https://www.ncbi.nlm.nih.gov/gene/553209", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001487", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001487", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018359", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018359", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036427", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036427", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057451", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057451", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:553209", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553209", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR16266", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16266", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16266:SF25", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16266:SF25", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23760", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23760", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25437", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25437", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021327269", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327269", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PQW9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q1J4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q1J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q1J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q1J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JP41", "url": "https://www.uniprot.org/uniprotkb/A0AC58JP41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JP41-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JP41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100921-43", "url": "https://zfin.org/ZDB-GENE-100921-43", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAAEPCSQIEAELYYLIARFLQSGPCQKSAQMLLQELHEYEIIPKRWSCDGEQFKRSFDDWVLLNQHIPADYLLRVCKQVGPLIDKHIPPSVPGVHSLLGTGRQSLLRTAKSSSHTLWSGSAVAALHRGRPPEPPISCAKSPNIVSIIGARQKTGVARFGHAFPSCAYQHMKMHRRILGHLSSVYCVAFDRTGRRIFTGSDDCLVKIWATDNGRLLATLRGHAAEISDMTVNFENTLLASASCDKIVRVWCLRTCAPVAVLQGHTASITSIQFSPSALGSSRFLATTGADGMVCFWQWNSFSMKFVDKPVKFMERSRPGVQISCSSFSSGGLFLATGGTDHMIRVYYLGTEMPVKFSDLDSHTDKVVAIQFCNNTDSLRFVSGSRDGTARIWHYQQQEWKSTVLDMTTRLPGSAVISGDDKSTKLVVTMVAWDRCDRSIITAVSNCLLKVWNSTNGQLLHVLLGHDDEVFVLEAHPFDSRILLSAGHDGNIYVWDLSKGQKIRNFFNMIEGQGHGAVFDCKFSVDGQHFACTDSHGHLLIFGFGCSQPYEMIPDQMFFHTDFRPLIRDSNNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRCQRLVPGRENCKEEQLVPQLGYMANGDGEVVEQVIGQQTADESQEESPLDDLIRQLQNQQDERVNQANPAGAEVAGGPLSPPNVGLRRSGQVEGVRQMHNNAPRSQMATERDLLAWSRRVVVNEVQAGIFRVMEDCRLAKGEVERSYYIIEKKRKSVPSTGSQPGDNVRTLRRPQRKAQQKRHAYQTRSTRTRRRSGSVQSFSRNEETEVESESEAEQEEDQNENSDGTSEGETQWENDSSSSDSSSEYSDWTADAGINLQPPKRTTRRPARVAVSSSSEDEEGTGQGEGEAAQTTKQAEKKKKPKQRSVPAGELEEWLPPSWIMETIPRRSPFVPQMGDELIYFRQGHQAYVRAVSRAKAYSINPQKQPWNRLNLRDQESVKVVGIKYEVGPPTLCCLKLAILDLTSGKMTNESFSLKYHDMPDVIDFLVLQQFYNEAKERNWQPGQRFRSIIDDAWWFGSLECQEPFESEYPDSLFQCYIVRWDNGEREKMSPWDIEPIPEEAPLPEEDGDSVPVTEDELQALLYSPQEGEWGLHTRDEECERVITAIDQLLTLDVAKAFSNPVNLREYPLYCTVVAYLTDLSTIRTRLVHRFYRRISALMWEVRYIEHNARTFNEPQSPIVTAAKTVSDVLLRFIRDQNCTDILDLYNKMKSEFSSEEDEEETVDVDSDTPGTSTGQRRSNSTPQKRGVVLDINAWHKQCKDLVRRMIVSSDSEPFRQPVDLFTYPDYRDIIDTPMDLGTVSETLTGGNYENPIEFAKDVRLIFSNSKAYTPNKKSRIYSMTLSLSAFFENQIIPIISDYKSAVQNQRRSQQRLMCSKRLQSSSPNSPKGKQKSGKKTLQMSAKARTRKSSQDSNVAQVDEDSQPSSSSSSSSSSSSSSSFSSEQAGANRVTRSQVTSSKSSGVFLPNGGRSSRRRRAVLTEEGEVSECESTSSSSSSTSASSSSSATSSSSSESDDSSAEVSGFADGGDHDYSKAPQHKQKGKAPAPPPPPSPPPPAPTIDNPKRKRKGEEEQSAEPEKRPRRTSSREEEEEEEEEEVDDEPEEEEEPDEEEEPEEEEEESDDENVISPSKRSNQRTPKSGRVNTRNQGRRTVLYNDDSEEEGPTSDPLNLGMSRSGRVRRMTERARVSHLMGWTH", "length": 1741, "header": "tr|A0A8M9PQW9-1|A0A8M9PQW9_DANRE Isoform 1 of Bromodomain and WD repeat-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=brwd3 PE=4 SV=2 CANONICAL=A0A8M9PQW9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PQW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQW9/entry#A0A8M9PQW9-1", "sequence": { "sequence": "MAAEPCSQIEAELYYLIARFLQSGPCQKSAQMLLQELHEYEIIPKRWSCDGEQFKRSFDDWVLLNQHIPADYLLRVCKQVGPLIDKHIPPSVPGVHSLLGTGRQSLLRTAKSSSHTLWSGSAVAALHRGRPPEPPISCAKSPNIVSIIGARQKTGVARFGHAFPSCAYQHMKMHRRILGHLSSVYCVAFDRTGRRIFTGSDDCLVKIWATDNGRLLATLRGHAAEISDMTVNFENTLLASASCDKIVRVWCLRTCAPVAVLQGHTASITSIQFSPSALGSSRFLATTGADGMVCFWQWNSFSMKFVDKPVKFMERSRPGVQISCSSFSSGGLFLATGGTDHMIRVYYLGTEMPVKFSDLDSHTDKVVAIQFCNNTDSLRFVSGSRDGTARIWHYQQQEWKSTVLDMTTRLPGSAVISGDDKSTKLVVTMVAWDRCDRSIITAVSNCLLKVWNSTNGQLLHVLLGHDDEVFVLEAHPFDSRILLSAGHDGNIYVWDLSKGQKIRNFFNMIEGQGHGAVFDCKFSVDGQHFACTDSHGHLLIFGFGCSQPYEMIPDQMFFHTDFRPLIRDSNNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRCQRLVPGRENCKEEQLVPQLGYMANGDGEVVEQVIGQQTADESQEESPLDDLIRQLQNQQDERVNQANPAGAEVAGGPLSPPNVGLRRSGQVEGVRQMHNNAPRSQMATERDLLAWSRRVVVNEVQAGIFRVMEDCRLAKGEVERSYYIIEKKRKSVPSTGSQPGDNVRTLRRPQRKAQQKRHAYQTRSTRTRRRSGSVQSFSRNEETEVESESEAEQEEDQNENSDGTSEGETQWENDSSSSDSSSEYSDWTADAGINLQPPKRTTRRPARVAVSSSSEDEEGTGQGEGEAAQTTKQAEKKKKPKQRSVPAGELEEWLPPSWIMETIPRRSPFVPQMGDELIYFRQGHQAYVRAVSRAKAYSINPQKQPWNRLNLRDQESVKVVGIKYEVGPPTLCCLKLAILDLTSGKMTNESFSLKYHDMPDVIDFLVLQQFYNEAKERNWQPGQRFRSIIDDAWWFGSLECQEPFESEYPDSLFQCYIVRWDNGEREKMSPWDIEPIPEEAPLPEEDGDSVPVTEDELQALLYSPQEGEWGLHTRDEECERVITAIDQLLTLDVAKAFSNPVNLREYPLYCTVVAYLTDLSTIRTRLVHRFYRRISALMWEVRYIEHNARTFNEPQSPIVTAAKTVSDVLLRFIRDQNCTDILDLYNKMKSEFSSEEDEEETVDVDSDTPGTSTGQRRSNSTPQKRGVVLDINAWHKQCKDLVRRMIVSSDSEPFRQPVDLFTYPDYRDIIDTPMDLGTVSETLTGGNYENPIEFAKDVRLIFSNSKAYTPNKKSRIYSMTLSLSAFFENQIIPIISDYKSAVQNQRRSQQRLMCSKRLQSSSPNSPKGKQKSGKKTLQMSAKARTRKSSQDSNVAQVDEDSQPSSSSSSSSSSSSSSSFSSEQAGANRVTRSQVTSSKSSGVFLPNGGRSSRRRRAVLTEEGEVSECESTSSSSSSTSASSSSSATSSSSSESDDSSAEVSGFADGGDHDYSKAPQHKQKGKAPAPPPPPSPPPPAPTIDNPKRKRKGEEEQSAEPEKRPRRTSSREEEEEEEEEEVDDEPEEEEEPDEEEEPEEEEEESDDENVISPSKRSNQRTPKSGRVNTRNQGRRTVLYNDDSEEEGPTSDPLNLGMSRSGRVRRMTERARVSHLMGWTH", "length": 1741, "header": "tr|A0A8M9PQW9-1|A0A8M9PQW9_DANRE Isoform 1 of Bromodomain and WD repeat-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=brwd3 PE=4 SV=2 CANONICAL=A0A8M9PQW9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q1J4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQW9/entry#A0A8M9Q1J4-1", "sequence": { "sequence": "MAAEPCSQIEAELYYLIARFLQSGPCQKSAQMLLQELHEYEIIPKRWSCDGEQFKRSFDDWVLLNQHIPADYLLRVCKQVGPLIDKHIPPSVPGVHSLLGTGRQSLLRTAKSSSHTLWSGSAVAALHRGRPPEPPISCAKSPNIVSIIGARQKTGVARFGHAFPSCAYQHMKMHRRILGHLSSVYCVAFDRTGRRIFTGSDDCLVKIWATDNGRLLATLRGHAAEISDMTVNFENTLLASASCDKIVRVWCLRTCAPVAVLQGHTASITSIQFSPSALGSSRFLATTGADGMVCFWQWNSFSMKFVDKPVKFMERSRPGVQISCSSFSSGGLFLATGGTDHMIRVYYLGTEMPVKFSDLDSHTDKVVAIQFCNNTDSLRFVSGSRDGTARIWHYQQQEWKSTVLDMTTRLPGSAVISGDDKSTKLVVTMVAWDRCDRSIITAVSNCLLKVWNSTNGQLLHVLLGHDDEVFVLEAHPFDSRILLSAGHDGNIYVWDLSKGQKIRNFFNMIEGQGHGAVFDCKFSVDGQHFACTDSHGHLLIFGFGCSQPYEMIPDQMFFHTDFRPLIRDSNNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRCQRLVPGRENCKEEQLVPQLGYMANGDGEVVEQVIGQQTADESQEESPLDDLIRQLQNQQDERVNQANPAGAEVAGGPLSPPNVGLRRSGQVEGVRQMHNNAPRSQMATERDLLAWSRRVVVNEVQAGIFRVMEDCRLAKGEVERSYYIIEKKRKSVPSTGSQPGDNVRTLRRPQRKAQQKRHAYQTRSTRTRRRSGSVQSFSRNEETEVESESEAEEEDQNENSDGTSEGETQWENDSSSSDSSSEYSDWTADAGINLQPPKRTTRRPARVAVSSSSEDEEGTGQGEGEAAQTTKQAEKKKKPKQRSVPAGELEEWLPPSWIMETIPRRSPFVPQMGDELIYFRQGHQAYVRAVSRAKAYSINPQKQPWNRLNLRDQESVKVVGIKYEVGPPTLCCLKLAILDLTSGKMTNESFSLKYHDMPDVIDFLVLQQFYNEAKERNWQPGQRFRSIIDDAWWFGSLECQEPFESEYPDSLFQCYIVRWDNGEREKMSPWDIEPIPEEAPLPEEDGDSVPVTEDELQALLYSPQEGEWGLHTRDEECERVITAIDQLLTLDVAKAFSNPVNLREYPLYCTVVAYLTDLSTIRTRLVHRFYRRISALMWEVRYIEHNARTFNEPQSPIVTAAKTVSDVLLRFIRDQNCTDILDLYNKMKSEFSSEEDEEETVDVDSDTPGTSTGQRRSNSTPQKRGVVLDINAWHKQCKDLVRRMIVSSDSEPFRQPVDLFTYPDYRDIIDTPMDLGTVSETLTGGNYENPIEFAKDVRLIFSNSKAYTPNKKSRIYSMTLSLSAFFENQIIPIISDYKSAVQNQRRSQQRLMCSKRLQSSSPNSPKGKQKSGKKTLQMSAKARTRKSSQDSNVAQVDEDSQPSSSSSSSSSSSSSSSFSSEQAGANRVTRSQVTSSKSSGVFLPNGGRSSRRRRAVLTEEGEVSECESTSSSSSSTSASSSSSATSSSSSESDDSSAEVSGFADGGDHDYSKAPQHKQKGKAPAPPPPPSPPPPAPTIDNPKRKRKGEEEQSAEPEKRPRRTSSREEEEEEEEEEVDDEPEEEEEPDEEEEPEEEEEESDDENVISPSKRSNQRTPKSGRVNTRNQGRRTVLYNDDSEEEGPTSDPLNLGMSRSGRVRRMTERARVSHLMGWTH", "length": 1740, "header": "tr|A0A8M9Q1J4-1|A0A8M9PQW9_DANRE Computationally mapped isoform of Bromodomain and WD repeat-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=brwd3 PE=4 SV=2 CANONICAL=A0A8M9PQW9-1" }, "locus": {} }, { "isoform_ac": "A0AC58JP41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQW9/entry#A0AC58JP41-1", "sequence": { "sequence": "MAAEPCSQIEAELYYLIARFLQSGPCQKSAQMLLQELHEYEIIPKRWSCDGEQFKRSFDDWVLLNQHIPADYLLRVCKQVGPLIDKHIPPSVPGVHSLLGTGRQSLLRTAKSSSHTLWSGSAVAALHRGRPPEPPISCAKSPNIVSIIGARQKTGVARFGHAFPSCAYQHMKMHRRILGHLSSVYCVAFDRTGRRIFTGSDDCLVKIWATDNGRLLATLRGHAAEISDMTVNFENTLLASASCDKIVRVWCLRTCAPVAVLQGHTASITSIQFSPSALGSSRFLATTGADGMVCFWQWNSFSMKFVDKPVKFMERSRPGVQISCSSFSSGGLFLATGGTDHMIRVYYLGTEMPVKFSDLDSHTDKVVAIQFCNNTDSLRFVSGSRDGTARIWHYQQQEWKSTVLDMTTRLPGSAVISGDDKSTKLVVTMVAWDRCDRSIITAVSNCLLKVWNSTNGQLLHVLLGHDDEVFVLEAHPFDSRILLSAGHDGNIYVWDLSKGQKIRNFFNMIEGQGHGAVFDCKFSVDGQHFACTDSHGHLLIFGFGCSQPYEMIPDQMFFHTDFRPLIRDSNNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRCQRLVPGRENCKEEQLVPQLGYMANGDGEVVEQVIGQQTADESQEESPLDDLIRQLQNQQDERVNQANPAGAEVAGGPLSPPNVGLRRSGQVEGVRQMHNNAPRSQMATERDLLAWSRRVVVNEVQAGIFRVMEDCRLAKGEVERSYYIIEKKRKSVPSTGSQPGDNVRTLRRPQRKAQQKRHAYQTRSTRTRRRSGSVQSFSRNEETEVESESEAEQEEDQNENSDGTSEGETQWENDSSSSDSSSEYSDWTADAGINLQPPKRTTRRPARVAVSSSSEDEEGTGQGEGEAAQTTKQAEKKKKPKQRSVPAGELEEWLPPSWIMETIPRRSPFVPQMGDELIYFRQGHQAYVRAVSRAKAYSINPQKQPWNRLNLRDQESVKVVGIKYEVGPPTLCCLKLAILDLTSGKMTNESFSLKYHDMPDVIDFLVLQQFYNEAKERNWQPGQRFRSIIDDAWWFGSLECQEPFESEYPDSLFQCYIVRWDNGEREKMSPWDIEPIPEEAPLPEEDGDSVPVTEDELQALLYSPQEGEWGLHTRDEECERVITAIDQLLTLDVAKAFSNPVNLREYPLYCTVVAYLTDLSTIRTRLVHRFYRRISALMWEVRYIEHNARTFNEPQSPIVTAAKTVSDVLLRFIRDQNCTDILDLYNKMKSEFSSEEDEEETVDVDSDTPGTSTGQRRSNSTPQKRGVVLDINAWHKQCKDLVRRMIVSSDSEPFRQPVDLFTYPDYRDIIDTPMDLGTVSETLTGGNYENPIEFAKDVRLIFSNSKAYTPNKKSRVRPAPLCFTPIINTQ", "length": 1396, "header": "tr|A0AC58JP41-1|A0AC58JP41_DANRE Computationally mapped isoform of Bromodomain and WD repeat-containing protein 3 isoform X3 OS=Danio rerio OX=7955 GN=brwd3 PE=4 SV=1 CANONICAL=A0A8M9PQW9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1710, "start_aa": "Thr", "end_pos": 1710, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1710", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:553209", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553209", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZZE0-1", "protein_name": "Bromodomain and WD repeat-containing protein 3", "gene_name": "Brwd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKNTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMSGNNLTSTEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQEESILDGIIRELQREQDLRLINEGDVPHFPINRSYSVNGALSSPNMDIPSSPNIGLRRSGQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKKPSYPIQRNDYQPSCGRSLRRTQRKRQHTYLTRSNIEHNSQASSQNSGVQGDSDSSSEEDETVGTSDASAEDPVVEWQSESSSSDSSSEYSDWTADAGINLQPPKRQTRQATQKIYSSSEDENVKSSEDRQKKPKQTRKKKGGLVSMAGEPNEEWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDTYNKIKAENPNSSDPEEDTEMVDLDSDGPGTSSGRRAKCRGRRQSLKCNPDAWKQQCKELLSLIYEREDSEPFRQPADPHSHPAQQQEGESSESVPPDRQDPSLSEDYQDVVDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENRIKNIISEYKSAIQSQKRRRPRYRKRLRSSSSSLSSSRAPSPKGKQKQMKLQPKNDQNTSVVYARTSSPFSSPVSDAAEGVSLYLLDDEGDGPFSPSSCSGYSRSGNSHDPGKAKSFRNRVLPAKQDHSLDGPLTNVDGREPRTGAKRKLLSASEEDESMGGEEKEMKETKEKAHLSSSESGELGSSLSSESTSGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRRQHATGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGGRGRGGGGGRGRGRGRGGRGASRGASRTKRARVADDEFDTMFAGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1799 }, "evidence": [ { "id": "RGD:1559445", "url": "https://alliancegenome.org/gene/RGD:1559445#orthology", "database": "AGR" }, { "id": "HGNC:17342", "url": "https://alliancegenome.org/gene/HGNC:17342#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100921-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100921-43#orthology", "database": "AGR" }, { "id": "MGI:3029414", "url": "https://alliancegenome.org/gene/MGI:3029414#orthology", "database": "AGR" }, { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1QKF7-1", "protein_name": "Bromodomain and WD repeat-containing protein 3", "gene_name": "brwd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADTTARNGSISPLESELYYLISRYLSTGPCRKAAEALVCELEENQLLPRRLDWEGNEHPRSYEDLVTANRHIAPDHLLQICKQIGPVLDREVPSGVPGVHSLLGAGRHSLLRTSKDCCASRWKTSTFAALHRGRPPERPLNCKDANIVEVCRGRELTGAQRFSSINPVSNYQHMKMHRRILGHLSAVYCIAFDRTGSRIFTGSDDALVKIWSSFDGRLHSTLRGHYAEISDLAVNFENTLIAAGSCDKTIRVWCLRTCAPVAVLQGHSGSITSLQFSPFVKGSKRYMVSTGTDATVCFWQWDVNNNEFSDRQHKFTERPRPGVQTVCSSFSPGGMFLATGSTDDVIRIYYLGSGSPEKLAELDSHTDKVDSIQFCHSGERFVSGSRDGTARIWRLHQRHQWKSVLLDMSATLPGSAPLTDDENFFKPKVTMVSWDRHDNTVITAVNNHLLKVWNSYTGQLLHVLKGHEAEVFVLEPHPYDPRIMLSAGHDGNVFVWDLIKGTKTMHYFNMIEGQGHGAVFDCKFTPDGHRFAMTDSHGHLVIFGFGSSKPYEKLPDQVFFHTDYRPLIRDTNGFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRFQRLVPGRENIADEHLVPQLGYVATSDGEVVEQVISQQSAESEEVRHSALDFAIRQLREHQDRQSGAPGEAGVPAAARVPEPGTPRRVSVNERMEVQSPPNVGLRRSGQVEGVRQMHQNAPRSQMATERDLQAWRRRVVIPELTPSGYRAQESFRIAKGDEEVNLYNTKKRRVTHSTFRDDSDEEGPCLKRTQSRKRQKNQERKENLAEEYIEFSCEEGEETASSEASEVEGSDIDSSAEDEEEWKSDSSSRSSSDYSDWTADAGISVRTSDSSRRRTTRRISSSEEEDEEDDEEEEEPADEEPAVGEEETSSPRKHKKAKSKTPKHSKPRPSINREISNEFRPPAWITDVVPRKSPFVPQMGDEVIYFRQGHEAYVDAVCRMNLYPINLDKQPWKKMQLRDQEFVKITGIKYEVCPPTLCCLKLTQIDPGTGKITDRTFSIKYHDMADVIDFLVLRQSYDEARNRVWTSNDRFRSVIDDAWWFGAIVCHEPYQSEYPDSHFQCFKVKWDNGETEKLSPWDVEAIPENAEQPESASAGVPVTDEEMMDILYKPQRGEWGDRGREQESARIIAGIEQLMTVDITAPFSGPVDLTQYPTYCTVIAYPTDLNTIKLRLKHNFYRRLSALIWDVKHIEQNAKTFNEPRSKIAQSAKIITNVLIKFISKLHCTDIMEIYNAVENMEYSDDEEMDDIDAPGTSAGQRLRQPSVEVVLDRDAWKDHCKRLLDYMFECEDSEPFRDPVDQSDYPDYTNIIDTPMDLGTVRQTLEEDRYENPIDVCKDIRLIFANAKAYTPNKRSKIYSMTLRLSAFFEENIRKIISDYKTAIKSSLKLRRSQRCRKKSQHQESVSFSQGSTRQKRATIKTQENTEQSTAKSTSAKVSGPERRRAHEAKETFRRSSSSSSGSDQDSKQSLSQSDEDDEHSSSSRAMRRETRATRKKAAQNKGAKSRRPESHVKMNGRSRSHERQKPRTSSDSDHEPSQGSDEASENESSPSVSRRPRTRKTAMAAVNKMKLIDTLGDEEGTDDEGGGGSTRPATRASKRSAVIQSSSDSDDEEEAAASQEESNESGSSASEGEKSAGSADSDSSSHSKKNSRTAGRRPCRRPAEKKETSPLTNGHGTKRQWEESDDNSEDGGSPIESENLESDNDLVVRRKSTRRTAKAAVSKIKKINNTDAEEEENCTRDRRQKHRSITQESENSSDEEVETTKTLKHPHQNGRKVDAKELKRCKAPSERQEQSPAAKQKTTHKKSSATDACMSTTQDSEELSDDVEKSVTHRKRIASEDEENQSDDADQRRVPKNRNRSSNARKQKLCASSDESSSESDEKADRGRIKSEGTSSDEWQKSDTSEEDKKTHPQRKPCPTVASKGVSLRTRPKKNYIMEDSEEEFSPKMDVQAKNGVKNQQANSRTRKPSGGGFKRKHGGSSESDADSKSSRSSDGNKLAEAQRKSAKRFKQLMGSTDSESDFETRCKSENGRAQRSQGKLPTVSRQRRKQSESDKGSNDNGSNFESEESESEASSGSRSSPKRRLRDRDRGTARSRKPRRVVSDDDSDVSFEKPRRGRRIQTRNKGKRTVNYQDSE", "length": 2182 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PE61-1", "protein_name": "PH-interacting protein", "gene_name": "phip", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAERKHVAQLKSELYFLIARFLEAGPCQDAAETLIREVQQKELLPKRIDWTGKEHPGSYENLVKLYRHISPDHLLQVCERVSPLLEREVPASVPGVNSLLGTGRQSVLRTNKSCKHVVWKGSALAALHCGRPPEPPVIFGSPPNIAETIHSRRLNGSYRLGQLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGHLLATLRGHAAEISDMAVNYENTLLAAGSCDKMIRVWCLQTCAPLAVLEGHAASITSLQFSPLCSGNKRFLSSTGADGTICFWQWDARTLKFGQRPSKFIERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYYFGGGQPEKISELESHTDKVDSIQFSHSGDRFVSGSRDGTARIWQLQQQDWRSILLDMATKLPGKYNPPPLEDKVTKLKVTMVAWDCNDNTVITAANNLTLKVWNSYTGNLIHVLMGHEDEVFVLEPHPFDSRVLFSAGHDGNAIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSRYDKIADQMFFHTDYRPLIRDAHNFVLDEQTQQAPHLMPPPFLVDVDGNPHPPRFQRLVPGRENCREEQLIPQMGLTSSGLNQVVSQQAAEGSSPLDSMIQRLQQEQDQRLGSDSRANRGSVSSPTEVTSPPNVGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVLVPELSLAIACKQEIWRTAKGEEEINIYRSERRRRSLHSQYHRENRHAIENAAEEGRRHQGNQHNYHTRLAVEETSRQSEPNEEEHSASEGETEVRPPSRESSDEEREEKEPWPDENSSSSDYSSDYSDWTADAGINLEPPKKTSVKKKKKKNASSSEEDGEKKKDSKKERRKEKPDKDGALPKKKKPKEKRKRIPELQNQGLTLEEWLPSNWITDTMPRRCPFTPQMGDEVYYFRQGHEAYVEMAKKNKIFSINPKKQPWHKLELREQELLKIVGIKYEVGLPTLCCLKLAFLDPDSGKLTGGSFSIKYHDMPDVIDFLVLRQQFDNARQRNWMIGDRFRAVIDDAWWFGTIESQEPYQAEYPDSLFQCYNVCWDNGDTEKMSPWDMEEVPDEVVFPEELGLSMALTQDEQKALLYKPLDGEWGSRTRNQECERIIRGINQLCTLDVAKPFELPVDLQAYPTYCTVVAYVTDLSTIRQRLENRFYRRMSSLMWEVRYIEHNAQTFNEPGAFIVRTAKFVSDLMLQFIKDQSCTDIIPLYNSMKKTAFSDSSDDEDEDEDEEHEAPCTSNRNKKRQQQQPMLRSLRSKPSSDPQAWKERCRELLELIFQCEDSEPFRQPVDLDEYPDYLDIVDTPMDFGTVLNRLLAGEYDTPMDLCKDVRLIFSNSKAYTPSKKSRIYSMSLRLSALFEEHISSILTDFKAAQSLHSERLTRQRLHTDRLTRQSVKKRRRRSSSHSSSASSPERKRRVSSRAPPRLDSAAPPTPAGPSRAPSLRQTHPQINGKAETPVVPGRTRSSARFGSPITDVAPAQSAPPPLVESSSSRVLRTQNPHSTAVSRENESSAVPPSNGGGARESRRKLRTPVKLTPGPVDHSSPPQNSLHLNGHSQVTVGMVRRGRGRPRLDTQIETPVDTPPPPLPKTSSKKKERKSKKDTESPRRNFSHEEELMLPTGDDGGASSTAQDSNLSDSGEYPKARGRPRITKTIDTPAPPSPKTLRRSSRRGNEEITPHTSGSAQSEEPEVYIGEDGSSKGQMKTRNQGRRTAFYNEEDSEEEQRQLLFEDASITFGTSSKGRVRKLTEKAKANLIGW", "length": 1807 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LKM2-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "Brwd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEAPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGPPPSLVDIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWKSILLDMAARISGDTSAEEERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENSADEHLVPQLGYVATSDGEVIEQVISLHTNDSGDASPESSVLDGMIRQLQQQQDLRLGVDQDVTANGLPNEEGTPRRGSFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQIATERDLQAWKRRVVVPEAPPGVFRRLEDIRIERGEEERNLYVIGRKKKTFQLPQKSNSMVLVSQSRQRTCRRKYANYSRRNAGQCELSSGNESSGSVRHETSCDQSEGSCSSEDDEWRSDRRSGSDSDSPSESSSQYSDWTADTGVHLEPPLRTSCRRRVTRFCSTSEDEMSTENISPPKRRRKRRKESKPKRESLRRTTPAELANMEPLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPSDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYSVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQDGEWGQRSRDEECERIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVHRFYRRLSALIWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQDCTNILELCNTSDSDGDSADDLDDSDLPKTSSGRRRVHNWKRRSRGSSCIESDWRRQCKALLILIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLEAGNYDSPVEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISFDFKIGQKFKEKLRRSQRFKQRQKCNGAVPVDRSMRSVKQKQFRSQTKVIPQLMCSPSQSTSSKVPLSATRKTSAGVSSGCTSGDSSDSAGSLERVRRHRAETLRSGSVLFGSEMEDFLATSSSSSSSNSSDESKESSGAQECSLRSGVLRSSNLRVTRTRAARRKAGSVSLENGCGRKATRKRVYLSDSDNHSVETDENLKSKAGSSRKVLRKCAAVAASKIKLMSDAEDSSSESPCSGRKLPHRNASAVARKKLLHNSDDQSLKSETEEVRDRNQALLMSSPHAVQNCISDSESDSDLQAARKTWHANGCTSHPAAACKAKSRPIESSEEDSRCHESDHGPSSTVDPLTSGQKLGADSISEEADSEPGSSALGKNTHLSKKAKILSDSEDCEEKYGERRGPEVEGSPVSEALREAVIVPQCLSHHGPETDVDSDGSAVREKSHSNVNDSVSRENGQRKKVSRKRFCSSDSESNLQVIQKSPIDQTSPSRITRSAGMVTDKTKLTSDAEDVSLESVCTRSKRRRKKPVRFACTTAKSIPSSEGKHARCEVPEEQSACRSSLAEPEQQGSAENASQAANADLDFEGSSSFEQTKSIQKRQMDSVCIRAPSKTQNSSAGPSQEDPKSHTQDSDISLSSESVLAQKAIGENNFEEELNYGLRRWNGRRLRTYGKAPLSRTAPVTPSLQAAAEVRVKRRRVHPEVDGEDIPGQMGSSGCGPDTSPKSSDLGSVTESDVDCTDNTKAQRRKKRKGKTRVLSQESVRKDREPHTKTRPCMFNEKEAVQMHSDTLKPKTVPEKIPRRCAAIAANKIKTMCNLKEVVSGPENVGIRTNSRKLPYRQASAAAKKKLLSVYKEDDALIHSENEEEVYLRRFRSQKEKAQQSP", "length": 2303 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2AHJ4-1", "protein_name": "Bromodomain and WD repeat-containing protein 3", "gene_name": "Brwd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFSHVFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTTRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEIPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMSGNNLTSAEDKVTKLKVTMVAWDRYDTTVITAVNNFLLKVWNSVTGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQEESILDGIIRELQREQDLRLINEGDVPHFPINRSYSVNGALSSPNMDIPSSPNIGLRRSGQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNSGVSRVQEECRNAKGDLEVSLYTVEKKKKPSYPIQRNDYQPSCGRSLRRTQRKRQHTYLTRSNIEHNSQASSQTSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSESSSSDSSSEYSDWIADAGINLQPPKRQTRQATQKIYSSSEDENLKLEDRQKKPKQTKKKKGGLVSMAGEPNEEWLAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEIGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPDGTAFPDEVGAGIPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINNLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIKQRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCSDILDTYNKIKAEDPDSSDLEEDSEMVDLDSDGPGTSSGRRAKCRGRRQSLKCNPDAWKKQCEELLSLIYEREDSEPFRQPADPQSYPVQQQQEGESSQSVPPDRQDPSLSEDYQDGIDTPMDFSTVKETLESGNYDSPLEFYKDVRQIFSNSKAYTSNKKSRIYSMTLRLSALFENHIKNIISDYKSAIQSQKRRRPRYRKRLRSSSSSLSSSRAPSPKGKQKQMKLQPKNDQNTSVAYARTSSPFSSPVSDAAEGVSLYLLDDEGDGPFSPSSFSGYSRSGNSHDPGKAKSFRNRVLPAKQDHSLDGPLTNVDGREPRTGAKRKLLSASEEDESMGGEEKEMKETKEQVHLSSSESGELGSSLSSESTSGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRKQHTNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGGRGRGGGGGRGRGRGRGGRGASRGSSRAKRARVADDEFDTMFSGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1799 }, "evidence": [ { "id": "RGD:1559445", "url": "https://alliancegenome.org/gene/RGD:1559445#orthology", "database": "AGR" }, { "id": "HGNC:17342", "url": "https://alliancegenome.org/gene/HGNC:17342#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100921-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100921-43#orthology", "database": "AGR" }, { "id": "MGI:3029414", "url": "https://alliancegenome.org/gene/MGI:3029414#orthology", "database": "AGR" }, { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M3B3-1", "protein_name": "PH-interacting protein", "gene_name": "Phip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPNIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPTKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDSTVITAVNNMTLKVWNSYTGQLIHVLTGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKVRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLVIFGFGSSSKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIPQMGVTSSGLNQVLSQQAIQDISPLDSMIQRLQQEQDLRRSGEAAVSSAGRLNRGSVSSTSEVHSPPNVGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKSYRSEEKRKHLTVAKENKILTVSKNHAHEHFLDLGDSKKQQANQHNYRTRSALEETPRPLEEIENGTSSSDEGEVLAVSGGTSEEEERAWHSDGSSSDYSSDYSDWTADAGINLQPPKKVPKHKTKKQDSSSDEEEESENQKQKHIKKERKKANEEKDGPTSPKKKKPKERKQKRLAVGELTENGLTLEEWLPSAWITDTLPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNRIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRRWNIGDRFRSVIDDAWWFGTIESQEPLQPEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDVECRSLIYKPLDGEWGANPRDEECERIVGGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRFSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIKHQHFLLFRDQTCYNIIPLYNSMKKKVLSDSEEEEKDADVPGTSTRKRKDHQPRRRLRNRAQSYDIQAWRKQCQELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTITKRRKRRNRSSSLSSSAASSPERKKRILKPQLKSEISTSPFSIPTRSVLPRHSAAQMNGKPESSSVVRTRSNRIAVDPVVTEQPSTSAATKAFVSKTNTSAMPGKTILENSVKHSKALSTLSSPDQLTFSHGTKNNSAKENMEKEKPVKRKMKSSVFTKASPLPKSSAVVDQGDCKNNVLIPGTIQVNGHGGQPSKLVKRGPGRKPKVEVNTSSGEVTHKKRGRKPKNLQCTTKQENSEQNNMHPIRGDVVPSSTCSFLSETNVVKEDLLQKKSRGGRKPKRKMKTQNLDSELIVPTNVKILRRSNRKKADDPIDEEEEFEELKGSEPHMRTRNQGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAKANLIGW", "length": 1830 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6RI45-1", "protein_name": "Bromodomain and WD repeat-containing protein 3", "gene_name": "BRWD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAPTQIEAELYYLIARFLQSGPCNKSAQVLVQELEEHQLIPRRLDWEGKEHRRSFEDLVAANAHIPPDYLLKICERIGPLLDKEIPQSVPGVQTLLGVGRQSLLRDAKDCKSTLWNGSAFAALHRGRPPELPVNYVKPPNVVNITSARQLTGCSRFGHIFPSSAYQHIKMHKRILGHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIILSAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLFGFGCSKYYEKIPDQMFFHTDYRPLIRDANNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENCKDEQLIPQLGYVANGDGEVVEQVIGQQTNDQDESILDGIIRELQREQDLRLINEGDVPHLPVNRAYSVNGALRSPNMDISSSPNIRLRRHSSQIEGVRQMHNNAPRSQMATERDLMAWSRRVVVNELNNGVSRVQEECRTAKGDIEISLYTVEKKKKPSYTTQRNDYEPSCGRSLRRTQRKRQHTYQTRSNIEHNSQASCQNSGVQEDSDSSSEEDETVGTSDASVEDPVVEWQSESSSSDSSSEYSDWTADAGINLQPPKRQTRQTTRKICSSSDEENLKSLEERQKKPKQTRKKKGGLVSIAGEPNEEWFAPQWILDTIPRRSPFVPQMGDELIYFRQGHEAYVRAVRKSKIYSVNLQKQPWNKMDLREQEFVKIVGIKYEVGPPTLCCLKLAFLDPISGKMTGESFSIKYHDMPDVIDFLVLHQFYNEAKERNWQIGDRFRSIIDDAWWFGTVESQQPFQPEYPDSSFQCYSVHWDNNEREKMSPWDMEPIPEGTAFPDEVGAGVPVSQEELTALLYKPQEGEWGAHSRDEECERVIQGINHLLSLDFASPFAVPVDLSAYPLYCTVVAYPTDLNTIRRRLENRFYRRISALMWEVRYIEHNARTFNEPDSPIVKAAKIVTDVLLRFIGDQSCTDILDTYNKIKAEERNSTDAEEDTEIVDLDSDGPGTSSGRKVKCRGRRQSLKCNPDAWKKQCKELLSLIYEREDSEPFRQPADLLSYPGHQEQEGESSESVVPERQQDSSLSEDYQDVIDTPVDFSTVKETLEAGNYGSPLEFYKDVRQIFNNSKAYTSNKKSRIYSMMLRLSALFESHIKNIISEYKSAIQSQKRRRPRYRKRLRSSSSSLSSSGAPSPKGKQKQMKLQPKNDQNTSVSHARTSSPFSSPVSDAAEGLSLYLLDDEPDGPFSSSSFGGYSRSGNSHDPGKAKSFRNRVLPVKQDHSLDGPLTNGDGREPRTGIKRKLLSASEEDENMGGEDKEKKETKEKSHLSTSESGELGSSLSSESTCGSDSDSESTSRTDQDYVDGDHDYSKFIQTRPKRKLRKQHGNGKRNWKTRGTGGRGRWGRWGRWSRGGRGRGGRGRGSRGRGGGGTRGRGRGRGGRGASRGATRAKRARIADDEFDTMFSGRFSRLPRIKTRNQGRRTVLYNDDSDNDNFVSTEDPLNLGTSRSGRVRKMTEKARVSHLMGWNY", "length": 1802 }, "evidence": [ { "id": "RGD:1559445", "url": "https://alliancegenome.org/gene/RGD:1559445#orthology", "database": "AGR" }, { "id": "HGNC:17342", "url": "https://alliancegenome.org/gene/HGNC:17342#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100921-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100921-43#orthology", "database": "AGR" }, { "id": "MGI:3029414", "url": "https://alliancegenome.org/gene/MGI:3029414#orthology", "database": "AGR" }, { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VDD9-1", "protein_name": "PH-interacting protein", "gene_name": "Phip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPTKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKVRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIPQMGVTSSGLNQVLSQQANQDISPLDSMIQRLQQEQDLRRSGEAGVSNASRVNRGSVSSTSEVHSPPNIGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKSYRSEEKRKHLTVAKENKILTVSKNHAHEHFLDLGDSKKQQANQHNYRTRSALEETPRPLEELENGTSSSDEGEVLAVSGGTSEEEERAWHSDGSSSDYSSDYSDWTADAGINLQPPKKVPKHKTKKPESSSDEEEESENQKQKHIKKERKKANEEKDGPTSPKKKKPKERKQKRLAVGELTENGLTLEEWLPSAWITDTLPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRPWNIGDRFRSVIDDAWWFGTIESQEPLQPEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDVECRSLIYKPLDGEWGANPRDEECERIVGGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRFSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEEEEKDADVPGTSTRKRKDHQPRRRLRNRAQSYDIQAWKKQCQELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNFKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTISKKRKKRNRSSSLSSSAASSPERKKRILKPQLKSEVSTSPFSIPTRSVLPRHNAAQMNGKPESSSVVRTRSNRVAVDPVVTEQPSTSSATKAFVSKTNTSAMPGKAMLENSVRHSKALSTLSSPDPLTFSHATKNNSAKENMEKEKPVKRKMKSSVFSKASPLPKSAAVIEQGECKNNVLIPGTIQVNGHGGQPSKLVKRGPGRKPKVEVNTSSGEVTHKKRGRKPKNLQCAKQENSEQNNMHPIRADVLPSSTCNFLSETNAVKEDLLQKKSRGGRKPKRKMKTHNLDSELIVPTNVKVLRRSNRKKTDDPIDEEEEFEELKGSEPHMRTRNQGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAKANLIGW", "length": 1821 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WWQ0-1", "protein_name": "PH-interacting protein", "gene_name": "PHIP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSCERKGLSELRSELYFLIARFLEDGPCQQAAQVLIREVAEKELLPRRTDWTGKEHPRTYQNLVKYYRHLAPDHLLQICHRLGPLLEQEIPQSVPGVQTLLGAGRQSLLRTNKSCKHVVWKGSALAALHCGRPPESPVNYGSPPSIADTLFSRKLNGKYRLERLVPTAVYQHMKMHKRILGHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLWDAGTLKINPRPAKFTERPRPGVQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVSGSRDGTARIWQFKRREWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLFSAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDCKCSPDGQHFACTDSHGHLLIFGFGSSSKYDKIADQMFFHSDYRPLIRDANNFVLDEQTQQAPHLMPPPFLVDVDGNPHPSRYQRLVPGRENCREEQLIPQMGVTSSGLNQVLSQQANQEISPLDSMIQRLQQEQDLRRSGEAVISNTSRLSRGSISSTSEVHSPPNVGLRRSGQIEGVRQMHSNAPRSEIATERDLVAWSRRVVVPELSAGVASRQEEWRTAKGEEEIKTYRSEEKRKHLTVPKENKIPTVSKNHAHEHFLDLGESKKQQTNQHNYRTRSALEETPRPSEEIENGSSSSDEGEVVAVSGGTSEEEERAWHSDGSSSDYSSDYSDWTADAGINLQPPKKVPKNKTKKAESSSDEEEESEKQKQKQIKKEKKKVNEEKDGPISPKKKKPKERKQKRLAVGELTENGLTLEEWLPSTWITDTIPRRCPFVPQMGDEVYYFRQGHEAYVEMARKNKIYSINPKKQPWHKMELREQELMKIVGIKYEVGLPTLCCLKLAFLDPDTGKLTGGSFTMKYHDMPDVIDFLVLRQQFDDAKYRRWNIGDRFRSVIDDAWWFGTIESQEPLQLEYPDSLFQCYNVCWDNGDTEKMSPWDMELIPNNAVFPEELGTSVPLTDGECRSLIYKPLDGEWGTNPRDEECERIVAGINQLMTLDIASAFVAPVDLQAYPMYCTVVAYPTDLSTIKQRLENRFYRRVSSLMWEVRYIEHNTRTFNEPGSPIVKSAKFVTDLLLHFIKDQTCYNIIPLYNSMKKKVLSDSEDEEKDADVPGTSTRKRKDHQPRRRLRNRAQSYDIQAWKKQCEELLNLIFQCEDSEPFRQPVDLLEYPDYRDIIDTPMDFATVRETLEAGNYESPMELCKDVRLIFSNSKAYTPSKRSRIYSMSLRLSAFFEEHISSVLSDYKSALRFHKRNTITKRRKKRNRSSSVSSSAASSPERKKRILKPQLKSESSTSAFSTPTRSIPPRHNAAQINGKTESSSVVRTRSNRVVVDPVVTEQPSTSSAAKTFITKANASAIPGKTILENSVKHSKALNTLSSPGQSSFSHGTRNNSAKENMEKEKPVKRKMKSSVLPKASTLSKSSAVIEQGDCKNNALVPGTIQVNGHGGQPSKLVKRGPGRKPKVEVNTNSGEIIHKKRGRKPKKLQYAKPEDLEQNNVHPIRDEVLPSSTCNFLSETNNVKEDLLQKKNRGGRKPKRKMKTQKLDADLLVPASVKVLRRSNRKKIDDPIDEEEEFEELKGSEPHMRTRNQGRRTAFYNEDDSEEEQRQLLFEDTSLTFGTSSRGRVRKLTEKAKANLIGW", "length": 1821 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q921C3-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "Brwd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEPSPARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEVPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGPPPSLVEIHRGRQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTLIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGPQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFDAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMSARISGDTSSEEERFMKPKVTMIAWNQDDSTVVTAVNDHVLKVWSSYTGQLLHNLLGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGIKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKFQRLVPGRENSADEHLVPQLGYVATSDGEVIEQIISLHTNDSGDASPESSVLDGMIRQLQQQQDQRLGVDQDGTANGLPSGEGTPRRGSFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQIATERDLQAWKRRVVVPEAPPGMFRRLEDIRIERGEEERNLYVIGRKKKTFQVPQKSNSMVLVSQSRQRTCRRKYANYSRRNADQCELSSGNESSGSVRHETSYDQSEGSCSSEDDEWRNDRRSGSDSDSSSDSSSQYSDWTADTGINLQPPLRMSCRRRVTRFCSTSEDEMSMENISPPKRRRKRRKESKPKRESLRRMTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQMGDEVMYFRQGHEAYIEAVRRNNIYELNPHKEPWRKMDLRDQELVKIVGLRYEVGPPTLCCLKLAFIDPATGRLTDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQPCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTETEKLSPWDMEPIPDNVDPPEELGASISVTSDELEKLLYKPQEGEWGQRSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALIWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQDCTNISELCNTSDNDEDDSADDLDDSDLPKTSSGRRKVHNWKRRSRASGCIESDWRRQCKALLILIFQCEDSEPFRQPVDLDEYPDYRDIIDTPMDFGTVRETLEAGNYDSPVEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISFDFKIGQKFKEKLRRSQRFKQRQNCNGAVPGDRRRRNVKQKQFKSQTKVIPQLMCPPSQSTSSKVPLSATRKTSAGVSSGFTSGDSSDSAGSLERVRRQRPEVLRSGSVLFGSEMEDFLATSSSSSASNSSEESKASPGARESSLRSGVLRGSNLGVTRTRAARRKAGSVSLENGCGRKATRKRVYLSDSDNNSVETDENLKNRKCGSSRKVLRKCAAVAASKIKLMSDAEDSSSESPCSGRKLPHRNASAVARKKLLHNSDDQSLKSETEELKDQNQSLLISGPHSVHNSISDSESDSDLRATRKTWNANGCTSHTAATCKTKSRPIESSEEDSRCHGSDHGPSSTGDPSTSGQKLRADSISEEADSEPESSVLCKNTHLCKKAKILSDSEDCEEKCGERRGPEVEGSPVSEALREAILAPQCLSHRGSETDVDSDGGAVREKSYSNENGSVSLENGQRRKVSRKSSSDKESNLQVTQKSPKDRSSPSRITQRASVATDKMKLTSDAEDLSLESVCTRSKRRRKKPARFACTPAKTALSSEEKHAHCEVPEAQPACRNKLPEPEHQDSAENPSQAASADLNSGGGSSFEQRKSIQSRQMGAVCVRPPPKTQSSSAGLSQENARSQTLDSETSLPSESVLTQKATVESNFEEELNYGLRRWNGRRLRTYGKAPLSRTAQVTPSLQASAEVGVKRRRMHPEVDGEDVPGQMGSSGCGPDTSPKASDLGSVTDSDVDCTDNTQTQRKKKRKGKARVLSKESVRKDREPHTKMRPCMLNEKDAVQMHSDTLKAKTVPEKVPRRCATVAANKIKMMCNLKEVVSGPENVGIRTISRKLPYRQASAAAKKKLLSVYKEDDAPIHSENEKELYLRRFRSRKEKAQPTPR", "length": 2304 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NSI6-1", "protein_name": "Bromodomain and WD repeat-containing protein 1", "gene_name": "BRWD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEPSSARRPVPLIESELYFLIARYLSAGPCRRAAQVLVQELEQYQLLPKRLDWEGNEHNRSYEELVLSNKHVAPDHLLQICQRIGPMLDKEIPPSISRVTSLLGAGRQSLLRTAKDCRHTVWKGSAFAALHRGRPPEMPVNYGSPPNLVEIHRGKQLTGCSTFSTAFPGTMYQHIKMHRRILGHLSAVYCVAFDRTGHRIFTGSDDCLVKIWSTHNGRLLSTLRGHSAEISDMAVNYENTMIAAGSCDKIIRVWCLRTCAPVAVLQGHTGSITSLQFSPMAKGSQRYMVSTGADGTVCFWQWDLESLKFSPRPLKFTEKPRPGVQMLCSSFSVGGMFLATGSTDHVIRMYFLGFEAPEKIAELESHTDKVDSIQFCNNGDRFLSGSRDGTARIWRFEQLEWRSILLDMATRISGDLSSEEERFMKPKVTMIAWNQNDSIVVTAVNDHVLKVWNSYTGQLLHNLMGHADEVFVLETHPFDSRIMLSAGHDGSIFIWDITKGTKMKHYFNMIEGQGHGAVFDCKFSQDGQHFACTDSHGHLLIFGFGCSKPYEKIPDQMFFHTDYRPLIRDSNNYVLDEQTQQAPHLMPPPFLVDVDGNPHPTKYQRLVPGRENSADEHLIPQLGYVATSDGEVIEQIISLQTNDNDERSPESSILDGMIRQLQQQQDQRMGADQDTIPRGLSNGEETPRRGFRRLSLDIQSPPNIGLRRSGQVEGVRQMHQNAPRSQIATERDLQAWKRRVVVPEVPLGIFRKLEDFRLEKGEEERNLYIIGRKRKTLQLSHKSDSVVLVSQSRQRTCRRKYPNYGRRNRSWRELSSGNESSSSVRHETSCDQSEGSGSSEEDEWRSDRKSESYSESSSDSSSRYSDWTADAGINLQPPLRTSCRRRITRFCSSSEDEISTENLSPPKRRRKRKKENKPKKENLRRMTPAELANMEHLYEFHPPVWITDTTLRKSPFVPQMGDEVIYFRQGHEAYIEAVRRNNIYELNPNKEPWRKMDLRDQELVKIVGIRYEVGPPTLCCLKLAFIDPATGKLMDKSFSIRYHDMPDVIDFLVLRQFYDEARQRNWQSCDRFRSIIDDAWWFGTVLSQEPYQPQYPDSHFQCYIVRWDNTEIEKLSPWDMEPIPDNVDPPEELGASISVTTDELEKLLYKPQAGEWGQKSRDEECDRIISGIDQLLNLDIAAAFAGPVDLCTYPKYCTVVAYPTDLYTIRMRLVNRFYRRLSALVWEVRYIEHNARTFNEPESVIARSAKKITDQLLKFIKNQHCTNISELSNTSENDEQNAEDLDDSDLPKTSSGRRRVHDGKKSIRATNYVESNWKKQCKELVNLIFQCEDSEPFRQPVDLVEYPDYRDIIDTPMDFGTVRETLDAGNYDSPLEFCKDIRLIFSNAKAYTPNKRSKIYSMTLRLSALFEEKMKKISSDFKIGQKFNEKLRRSQRFKQRQNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTAYLGTHKTSAGISSGVTSGDSSDSAESSERRKRNRPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARESSSRSGLSRSSNLRVTRTRAAQRKTGPVSLANGCGRKATRKRVYLSDSDNNSLETGEILKARAGNNRKVLRKCAAVAANKIKLMSDVEENSSSESVCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDENQLLPVSSSHTAQSNVDESENRDSESESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHACNRTAGPSTSVQKLKAESISEEADSEPGRSGGRKYNTFHKNASFFKKTKILSDSEDSESEEQDREDGKCHKMEMNPISGNLNCDPIAMSQCSSDHGCETDLDSDDDKIEKPNNFMKDSASQDNGLSRKISRKRVCSSDSDSSLQVVKKSSKARTGLLRITRRCAATAANKIKLMSDVEDVSLENVHTRSKNGRKKPLHLACTTAKKKLSDCEGSVHCEVPSEQYACEGKPPDPDSEGSTKVLSQALNGDSDSEDMLNSEHKHRHTNIHKIDAPSKRKSSSVTSSGEDSKSHIPGSETDRTFSSESTLAQKATAENNFEVELNYGLRRWNGRRLRTYGKAPFSKTKVIHDSQETAEKEVKRKRSHPELENVKISETTGNSKFRPDTSSKSSDLGSVTESDIDCTDNTKTKRRKTKGKAKVVRKEFVPRDREPNTKVRTCMHNQKDAVQMPSETLKAKMVPEKVPRRCATVAANKIKIMSNLKETISGPENVWIRKSSRKLPHRNASAAAKKKLLNVYKEDDTTINSESEKELEDINRKMLFLRGFRSWKENAQ", "length": 2320 }, "evidence": [ { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VC96-1", "protein_name": "BRWD3", "gene_name": "BRWD3", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "METRQPSSGDDLKPELYFLISKFLAAGPLEETAKVLIRELEEKKVLPRRLDWQGNEHEQTFEELERKYKHIGANHLLEICSRLGPLVDRELPPSVPGINSLLGTGRQNLLRTKETVYCHRSLRDYCTRLNGVSLPDSVLTKPTHNLDRVLTGREHGGEVRRKLLVPTDLYRRTKLLRRTVGHLSSVYCVLFDRTGRYIITGADDLLIKIWSAADGRLLATLRGASSEITDIAINLDNTMLAAGSLDHILRVWDMQTTSPIAVLSAHTGMITSVNFCPSPRSDLKYLVTTSTDGSIAFWQYSTPRGQKITFAPKPTQYHEKLRPGQAQMMCTTFSPGGIFLAAGSADHHVRVYMMGEDGPKRILETEAYTDAVDSVQWSHRGLRFISGSKDGTAHIWTFESQQWKSSKLCMTERLASCPEPEEGKRLKVTMVAWDASDRYVITAVNDFTIKIWDSKSAKLHRVLRGHKDELYVLESNPRDEHVLLSAGHDGQVFLWDIEQGVCVANFLNDIDGQGHGSVFDAKWSPDGTMIAATDSHGHILIFGLGVCIEKYKMLPTELFFHTDFRPLLRDAQHHVVDEQTQIMPHLMPPPFLVDADGNPHPSRFQRFVPGRESCSLDQLIPNLTVGVDGVVIDDGGAGGDAVVAAAPAEAPPAALPPAAAGGPQGANYSHIDRMIAALANRQSVNVNANDANPTNGNQSFERLTNRQMPDSNGRQSSRGNVLGSRLSTPRQGWGAAAAAPVEDQAGPSQPPAEPAAEPGQAQVQQALPLKFIRRTYVRPMKYPQLQNLKQTIYSAGQFEKQEYKREMRRRPIMINTASAASSQQPGSVGRPRNTRGNGGGARAGRRRGPQPAGGQPQPAYRTRAVRDQEPEHYDEVAPPPEEEEEDVSSNSSGDTSYSNVEENLEDSSDESETDSSDYSDWVADTPGPNLEPPKRSKRKPLSRRPRSSDDSSDDERAGRSRGGQVTARKVGRKTVLFPPTDANGEIPELYRPAEWLSEVIPRKAPYYPQMGDEVVYFRQGHAKYLDAVRLKKVYKLSHSSEPWNFHTLRDHELVRVIGIKYEIRPPRLCCLKLAIIDEEGNMTGTTFKIKYHDMPDVLDFLVLRQTFDLAVQRNWSIGDRFRCMIVDGWWMGQIESRHALSADFPDSSFMCFRVRWDNGEYEFMSPWDMEPIDQQRVPDEVGGAVPVLPEEIRATLYQPKSEEWHRGDRDGTCRRIINGLEQVMRLSIAEHFLAPVDLNIYPDYAYLIEYPIDLTTIKSRFENHFYRRITSAQFDVRYLATNAEQYNRRHAIIVKHSRIVTDLCLRIIREPDEIDVAAVYHQLADVYHSSESENEVDSDVVPSTSTGPTTSAAAAAARQRVSSARRSTRIHSEGDWRADCRQLLDLMWARTDSAPFREPVDTIDFPDYLEIIATPMDLRTVKEDLLGGNYDDPLDFAKDVRLIFQNSKNYNTNKRSRIYAMTLRLSALFESHIKTVVTSWKAALRRANKNKSGSSGGGRGGSSSSPNKRVKKERSTRRNQKPTAAARRLPVANSSEDEDEEDDDDDDDDDDEEEASTRGRSRRRNGVAVSASSSGSNRVTSSSAAQQRRGKSSSSEEEEEEETSAQATSDASSDEEERAQSNDSSPQQTRTRRARQRQRLSDDSNINDSEDSYNPNEGRGSRRRPGAARPSSNRQTNGHSSKRRRLNKSPANAAPGPSLPRRTRRIAGSSAEEAASHSQHDESTQDSQIGRRKGRSASSRSIGNGPSTSAAAAANSSLESPSRNTRANGTRTSSHLGAENDHSYHLPVRNGRIIESDTDSPVIRPTRQSAKRALMDWGRGSDIEEEEEEEEEDSEEAEEILPTPTKDDLPSTSRAALAQAAAGPSRQLRTNRNTVVRPAQSDDDDDDDSDNEPLANNQQKNYQSPAKSSSTATVAPHPLSLRRRLASPPERNTHMTRSHATSTTSSAAASRAEQQPAVSTHDHNYLGNVNSSRAPRRILSRHQRNADELDTSLDVLENSRLLSAIANHRRPTSTTNSNSASNVVTRRLRGRASQANSHDEDHEEEEAAASDEGTDGGSSSQSYEDEDEDSDSEDNQPLTSYVSPSNGRPRRKAKTSSSSATTQERPLRRTRRPPSNNSIANDNDDDDDYVVPRSRRANRGGNQRAGRNQKRPRYNEQSEEEEAAAGYSHRSKRIRNGDAHASSQERSQASTERDQEEEEDGTSVDSEEQQVNVSSRGRVRKPSAKARGIFKE", "length": 2232 }, "evidence": [ { "id": "RGD:1559445", "url": "https://alliancegenome.org/gene/RGD:1559445#orthology", "database": "AGR" }, { "id": "HGNC:17342", "url": "https://alliancegenome.org/gene/HGNC:17342#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100921-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100921-43#orthology", "database": "AGR" }, { "id": "MGI:3029414", "url": "https://alliancegenome.org/gene/MGI:3029414#orthology", "database": "AGR" }, { "id": "FB:FBgn0011785", "url": "https://alliancegenome.org/gene/FB:FBgn0011785#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1014, "end_pos": 1016, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1243, "end_pos": 1245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1285, "end_pos": 1287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 839, "end_pos": 841, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PQW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQW9" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 1155, "end_pos": 1225, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1710 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1014, "end_pos": 1016 }, { "start_pos": 1243, "end_pos": 1245 }, { "start_pos": 1285, "end_pos": 1287 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 452, "end_pos": 454 }, { "start_pos": 839, "end_pos": 841 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A3KQ79-1", "uniprot_ac": "A3KQ79", "uniprot_id": "A3KQ79_DANRE", "mass": { "chemical_mass": 25327.0, "monoisotopic_mass": 25327.0 }, "refseq": { "ac": "NP_001108359", "name": "uncharacterized protein LOC335411 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108359" }, "gene_names": [ { "name": "si:dkeyp-46h3.2", "type": "recommended", "evidence": [ { "id": "A3KQ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ79" } ] }, { "name": "fj09f07", "type": "synonym", "evidence": [ { "id": "NP_001108359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108359" }, { "id": "A3KQ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ79" } ] }, { "name": "si:dkeyp-46h3.2", "type": "synonym", "evidence": [ { "id": "NP_001108359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108359" } ] }, { "name": "wu:fj09f07", "type": "synonym", "evidence": [ { "id": "NP_001108359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108359" }, { "id": "A3KQ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ79" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC335411 precursor", "type": "synonym", "evidence": [ { "id": "A3KQ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ79/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC335411 precursor", "type": "synonym", "evidence": [ { "id": "NP_001108359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108359" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH445739.1, CN024649.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708832, SAMEA898399 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH445739.1 and EH534347.1. On or before Mar 13, 2014 this sequence version replaced XP_005170166.1, NP_001108359.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001108359", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108359" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KQ79", "url": "https://www.uniprot.org/uniprotkb/A3KQ79" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkeyp-46h3.2", "url": "https://www.uniprot.org/uniprotkb/A3KQ79", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-7351", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7351", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092498", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092498", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22836", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22836", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "335411", "url": "https://www.ncbi.nlm.nih.gov/gene/335411", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:335411", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:335411", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHFADES", "url": "https://omabrowser.org/oma/group/CHFADES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A3KQ79", "url": "https://www.orthodb.org/?gene=A3KQ79", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001108359", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108359", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A3KQ79", "url": "https://www.uniprot.org/uniprotkb/A3KQ79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KQ79-1", "url": "https://www.uniprot.org/uniprotkb/A3KQ79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-7351", "url": "https://zfin.org/ZDB-GENE-030131-7351", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVSLRVFLSLLLGCSLSAGVTLNLAPLDTDVSPRTKTIVICNGDRAVLKCAYGVLQITDANYGRTNRRDCSGRRPVLPQNTNCIFNALAPVSQSCNGLRSCELFATTDIFTDPCPDMRSYLSVTYYCLPPEIRSSVVCENAIVNFKCEDGSLVHIHAANYGRTDSSTCAAGRPASQTAKTNCYASNSQTLVANACEGKNVCAISASNGVFSDPCYGTYKYLYTAYSCVPQFYWS", "length": 234, "header": "tr|A3KQ79-1|A3KQ79_DANRE Isoform 1 of Uncharacterized protein LOC335411 precursor OS=Danio rerio OX=7955 GN=si:dkeyp-46h3.2 PE=1 SV=1 CANONICAL=A3KQ79-1" }, "isoforms": [ { "isoform_ac": "A3KQ79-1", "url": "https://www.uniprot.org/uniprotkb/A3KQ79/entry#A3KQ79-1", "sequence": { "sequence": "MVSLRVFLSLLLGCSLSAGVTLNLAPLDTDVSPRTKTIVICNGDRAVLKCAYGVLQITDANYGRTNRRDCSGRRPVLPQNTNCIFNALAPVSQSCNGLRSCELFATTDIFTDPCPDMRSYLSVTYYCLPPEIRSSVVCENAIVNFKCEDGSLVHIHAANYGRTDSSTCAAGRPASQTAKTNCYASNSQTLVANACEGKNVCAISASNGVFSDPCYGTYKYLYTAYSCVPQFYWS", "length": 234, "header": "tr|A3KQ79-1|A3KQ79_DANRE Isoform 1 of Uncharacterized protein LOC335411 precursor OS=Danio rerio OX=7955 GN=si:dkeyp-46h3.2 PE=1 SV=1 CANONICAL=A3KQ79-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Expressed sequence tag analysis of expression profiles of zebrafish testis and ovary.", "journal": "Gene", "date": "2002", "authors": "Zeng Sheng, Gong Zhiyuan", "evidence": [ { "database": "UniProtKB", "id": "A3KQ79", "url": "https://www.uniprot.org/uniprotkb/A3KQ79" } ], "reference": [ { "type": "PubMed", "id": "12234666", "url": "https://glygen.org/publication/PubMed/12234666" } ] }, { "title": "Hematopoietic gene expression profile in zebrafish kidney marrow.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2004", "authors": "Song Huai-Dong, Sun Xiao-Jian, Deng Min, Zhang Guo-Wei, Zhou Yi, Wu Xin-Yan, Sheng Yan, Chen Yi, Ruan Zheng, Jiang Chun-Lei, Fan Hui-Yong, Zon Leonard I, Kanki John P, Liu Ting Xi, Look A Thomas, Chen Zhu", "evidence": [ { "database": "UniProtKB", "id": "A3KQ79", "url": "https://www.uniprot.org/uniprotkb/A3KQ79" } ], "reference": [ { "type": "PubMed", "id": "15520368", "url": "https://glygen.org/publication/PubMed/15520368" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A3KQ79", "url": "https://www.uniprot.org/uniprotkb/A3KQ79" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:335411", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:335411", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A3KQ79", "url": "https://www.uniprot.org/uniprotkb/A3KQ79" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A3KQ79", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ79" }, { "id": "PS50228", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUEL-type lectin", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 128, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A4JYR2-1", "uniprot_ac": "A4JYR2", "uniprot_id": "A4JYR2_DANRE", "mass": { "chemical_mass": 18610.0, "monoisotopic_mass": 18610.0 }, "refseq": { "ac": "NP_001077339", "name": "novel immune-type receptor 14b precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077339" }, "gene_names": [ { "name": "nitr14b", "type": "recommended", "evidence": [ { "id": "A4JYR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4JYR2" } ] }, { "name": "nitr14b", "type": "synonym", "evidence": [ { "id": "NP_001077339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077339" } ] }, { "name": "si:dkey-149k8.5", "type": "synonym", "evidence": [ { "id": "NP_001077339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077339" }, { "id": "A4JYR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4JYR2" } ] } ], "protein_names": [ { "name": "Novel immune-type receptor 14b precursor", "type": "synonym", "evidence": [ { "id": "A4JYR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A4JYR2/entry#names_and_taxonomy" } ] }, { "name": "immune-type receptor protein", "type": "synonym", "evidence": [ { "id": "NP_001077339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077339" } ] }, { "name": "novel immune-type receptor 14b precursor", "type": "synonym", "evidence": [ { "id": "NP_001077339", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077339" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CU458983.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505375, SAMEA3505383 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## NMD candidate :: translation inferred from conservation ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CU458983.1. On Apr 5, 2007 this sequence version replaced XP_001337022.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001077339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077339" } ] }, { "annotation": "Phylogenetic analyses indicate that the V domains encoded by the nitr13 and nitr14 genes are more similar to each other than any other zebrafish NITR suggesting that these genes arose from a tandem gene duplication event.", "evidence": [ { "database": "RefSeq", "id": "NP_001077339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077339" }, { "database": "PubMed", "id": "18330557", "url": "https://glygen.org/publication/PubMed/18330557" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A4JYR2", "url": "https://www.uniprot.org/uniprotkb/A4JYR2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nitr14b", "url": "https://www.uniprot.org/uniprotkb/A4JYR2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070108-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100148851", "url": "https://www.ncbi.nlm.nih.gov/gene/100148851", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "A4JYR2", "url": "https://www.ebi.ac.uk/intact/interactors/id:A4JYR2*", "database": "IntAct", "categories": [ "Other" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100148851", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148851", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ENSTTEM", "url": "https://omabrowser.org/oma/group/ENSTTEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A4JYR2", "url": "https://www.orthodb.org/?gene=A4JYR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19433", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19433", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19433:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19433:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001077339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077339", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A4JYR2", "url": "https://www.uniprot.org/uniprotkb/A4JYR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A4JYR2-1", "url": "https://www.uniprot.org/uniprotkb/A4JYR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070108-4", "url": "https://zfin.org/ZDB-GENE-070108-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MILWAFVTVLCVARTAHSRIEQPEKVMIVELGNSVTLRCISCNNNIFWYKQVAGQQPRVISAFQKLSEPIFYNKYKNERFWGKRLSCSTNLTISDIIQSDEAVYYCASREFYTEFGNGTHLKIKGHQAAAYKNSNLDHLNSSIKCRQKFNENSTTEMCNYL", "length": 161, "header": "tr|A4JYR2-1|A4JYR2_DANRE Isoform 1 of Novel immune-type receptor 14b precursor OS=Danio rerio OX=7955 GN=nitr14b PE=1 SV=1 CANONICAL=A4JYR2-1" }, "isoforms": [ { "isoform_ac": "A4JYR2-1", "url": "https://www.uniprot.org/uniprotkb/A4JYR2/entry#A4JYR2-1", "sequence": { "sequence": "MILWAFVTVLCVARTAHSRIEQPEKVMIVELGNSVTLRCISCNNNIFWYKQVAGQQPRVISAFQKLSEPIFYNKYKNERFWGKRLSCSTNLTISDIIQSDEAVYYCASREFYTEFGNGTHLKIKGHQAAAYKNSNLDHLNSSIKCRQKFNENSTTEMCNYL", "length": 161, "header": "tr|A4JYR2-1|A4JYR2_DANRE Isoform 1 of Novel immune-type receptor 14b precursor OS=Danio rerio OX=7955 GN=nitr14b PE=1 SV=1 CANONICAL=A4JYR2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Evidence for a transposition event in a second NITR gene cluster in zebrafish.", "journal": "Immunogenetics", "date": "2008", "authors": "Yoder Jeffrey A, Cannon John P, Litman Ronda T, Murphy Carly, Freeman Jennifer L, Litman Gary W", "evidence": [ { "database": "UniProtKB", "id": "A4JYR2", "url": "https://www.uniprot.org/uniprotkb/A4JYR2" }, { "database": "RefSeq", "id": "NP_001077339", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077339" } ], "reference": [ { "type": "PubMed", "id": "18330557", "url": "https://glygen.org/publication/PubMed/18330557" } ] }, { "title": "The medaka novel immune-type receptor (NITR) gene clusters reveal an extraordinary degree of divergence in variable domains.", "journal": "BMC Evol. Biol.", "date": "2008", "authors": "Desai Salil, Heffelfinger Amy K, Orcutt Timothy M, Litman Gary W, Yoder Jeffrey A", "evidence": [ { "database": "UniProtKB", "id": "A4JYR2", "url": "https://www.uniprot.org/uniprotkb/A4JYR2" } ], "reference": [ { "type": "PubMed", "id": "18565225", "url": "https://glygen.org/publication/PubMed/18565225" } ] }, { "title": "Developmental and tissue-specific expression of NITRs.", "journal": "Immunogenetics", "date": "2010", "authors": "Yoder Jeffrey A, Turner Poem M, Wright Phillip D, Wittamer Val\u00e9rie, Bertrand Julien Y, Traver David, Litman Gary W", "evidence": [ { "database": "UniProtKB", "id": "A4JYR2", "url": "https://www.uniprot.org/uniprotkb/A4JYR2" } ], "reference": [ { "type": "PubMed", "id": "20012603", "url": "https://glygen.org/publication/PubMed/20012603" } ] }, { "title": "Construction of a large extracellular protein interaction network and its resolution by spatiotemporal expression profiling.", "journal": "Mol. Cell. Proteomics", "date": "2010", "authors": "Martin Stephen, S\u00f6llner Christian, Charoensawan Varodom, Adryan Boris, Thisse Bernard, Thisse Christine, Teichmann Sarah, Wright Gavin J", "evidence": [ { "database": "UniProtKB", "id": "A4JYR2", "url": "https://www.uniprot.org/uniprotkb/A4JYR2" } ], "reference": [ { "type": "PubMed", "id": "20802085", "url": "https://glygen.org/publication/PubMed/20802085" } ] }, { "title": "The impact of gene expression regulation on evolution of extracellular signaling pathways.", "journal": "Mol. Cell. Proteomics", "date": "2010", "authors": "Charoensawan Varodom, Adryan Boris, Martin Stephen, S\u00f6llner Christian, Thisse Bernard, Thisse Christine, Wright Gavin J, Teichmann Sarah A", "evidence": [ { "database": "UniProtKB", "id": "A4JYR2", "url": "https://www.uniprot.org/uniprotkb/A4JYR2" } ], "reference": [ { "type": "PubMed", "id": "20935258", "url": "https://glygen.org/publication/PubMed/20935258" } ] } ], "pathway": [ { "id": "dre:100148851", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148851", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A075B657-1", "protein_name": "T cell receptor delta variable 1", "gene_name": "Trdv1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGMRLQVLAWLLTFQAAWVNTQMLHQSPQSLTIQEGDEVTMSCNLSTSLYALLWYRQGDDGSLVSLVTLQKGGDEKSKDKITANLDKKMQQSSLWIQASQPSHSGTYLCGGK", "length": 112 }, "evidence": [ { "id": "RGD:11454121", "url": "https://alliancegenome.org/gene/RGD:11454121#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A087WSZ9-1", "protein_name": "T cell receptor alpha variable 30", "gene_name": "TRAV30", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METLLKVLSGTLLWQLTWVRSQQPVQSPQAVILREGEDAVINCSSSKALYSVHWYRQKHGEAPVFLMILLKGGEQKGHDKISASFNEKKQQSSLYLTASQLSYSGTYFCGTE", "length": 112 }, "evidence": [ { "id": "RGD:11454121", "url": "https://alliancegenome.org/gene/RGD:11454121#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0B4J273-1", "protein_name": "T cell receptor alpha variable 34", "gene_name": "TRAV34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METVLQVLLGILGFQAAWVSSQELEQSPQSLIVQEGKNLTINCTSSKTLYGLYWYKQKYGEGLIFLMMLQKGGEEKSHEKITAKLDEKKQQSSLHITASQPSHAGIYLCGAD", "length": 112 }, "evidence": [ { "id": "RGD:11454121", "url": "https://alliancegenome.org/gene/RGD:11454121#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A8M1PDP1-1", "protein_name": "Novel immune-type receptor 4a isoform 6 precursor", "gene_name": "nitr4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNHIIYVIIFLFHPQVSGKNNCTVDQVDEVLTTQEGHIVLLPCLLLEDHFHRVIWYKQVLGEKPVVIVSSYHHSQPNEFSSDFKETQRFHAVRKADSFNLTIRRTLKSDSGTYFCGSAFANVVSFGTGTILLVKGADLKPAVIQHPVHAFIKPESNVTLRCSVEGKTCDKGVQSVYWFRQSLNTTHQGIVYTHGKSKNECADSSDTQSCLQNLAKMSVDVSEAGLYYCSVVTCDEVLFGNGTTLVIKDGFISESIQKCILIGLTVLSAVSLTINILLSLPLRRNGGKPQQMQTNDDITRVQFQNADDVNYAALNLSSKRGQRKMTLEKTPTQTNAAR", "length": 337 }, "evidence": [ { "id": "RGD:11454121", "url": "https://alliancegenome.org/gene/RGD:11454121#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LWD2-1", "protein_name": "Ig-like domain-containing protein", "gene_name": "Trav34l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGMLLQVLVGLLMFPAVWVNTQKLQQSPQSLTIQEGDELTMSCNSSSSLYALHWYRQGRDGGPIFLVTLQKGGDEKRKDKITAKLDKKMRQSFLSIQASQPSYAGTYLCAGSAQWSIDCRGLSPNLQLGHSCSDTGPLRQD", "length": 141 }, "evidence": [ { "id": "RGD:11454121", "url": "https://alliancegenome.org/gene/RGD:11454121#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070108-4#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58FZ12-1", "protein_name": "Novel immune-type receptor 12 isoform X1", "gene_name": "nitr12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWPNAQRTLTMIAFLLIFFLPFRTGLITSDAVFQKKVLESFTAGQTVTLDCLISVNLENYFSWFKQTLGEAPTCIVSLYAESSTPVFYGEFKNNHRMSVQKEKNTFVLIIKEAKPSDAGIYYCGARDYDLITFSNGLFLNYKVASTKQHHIKQFLSGPNLGTEHEPEFNPGDSVNLHCSVLTERCEENHRIYWFRHESGDAHPGLIYKDGNTTDQCEKRSEKDVQSCIYNLPKKNLNLTDAGVYYCAVATCGEILFGNGSRINIREASSKFSWTDVKVPVLASTNILCLVIIVILLCKRAQKQKQKFSESQPLQTTLSSTPANEDISYAAVHLSGSSRHETEKGSCTHVVYSTARGYSIKE", "length": 361 }, "evidence": [ { "id": "RGD:11454121", "url": "https://alliancegenome.org/gene/RGD:11454121#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58G0B8-1", "protein_name": "Novel immune-type receptor 1c isoform X1", "gene_name": "nitr1c", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334650" }, { "id": "A0A8N7URD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021334650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334650" } ] } ], "disease": [ { "disease_id": "DOID:0080815", "recommended_name": { "id": "DOID:0080815", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080815", "name": "childhood-onset asthma", "description": "A chronic asthma that is characterized by first presentation in early childhood." }, "synonyms": [ { "id": "DOID:0080815", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080815", "name": "childhood asthma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080815", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080815" } ] }, { "disease_id": "DOID:1205", "recommended_name": { "id": "DOID:1205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1205", "name": "allergic disease", "description": "An immune system disease that is an exaggerated immune response to allergens, such as insect venom, dust mites, pollen, pet dander, drugs or some foods." }, "synonyms": [ { "id": "DOID:1205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1205", "name": "hypersensitivity", "description": "" }, { "id": "DOID:1205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1205", "name": "hypersensitivity reaction type I disease", "description": "" }, { "id": "DOID:1205", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1205", "name": "allergic hypersensitivity disease", "description": "" } ], "unlinked_id_list": [ "DOID:0080811", "DOID:0060502", "DOID:0060503", "DOID:0060904" ], "evidence": [ { "id": "1205", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1205" } ] }, { "disease_id": "DOID:2841", "recommended_name": { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF13771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021334650", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334650", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PSY4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PSY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7URD4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7URD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U0C7", "url": "https://www.uniprot.org/uniprotkb/A0AB32U0C7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U0C7-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32U0C7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGQ3", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGQ4", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGQ6", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGR1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGR1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGR2", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGR2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGR3", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGR3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGR8", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGR8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGS0", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGS0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGS6", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGS6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGU9", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGU9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGV4", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-417", "url": "https://zfin.org/ZDB-GENE-081104-417", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGSGQSPSTYRIICALCKTSDETETTGPLSSKEDISAHQNCLLFSSNIYCKNSPTYDDLFGFDLEDVKKEQRRGQKLRCYFCNKTGATVGCEIKRCPRSFHYPCAIKADARAIEDFSTGTYRVYCKSHDPNPIEINDEIDNDVDLVLASVEKHVPAEQHNQSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESVSLSVLNKTHLRHIEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 531, "header": "tr|A0A8N7URD4-1|A0A8N7URD4_DANRE Isoform 1 of PHD finger protein 11 isoform X1 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PSY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0A8M9PSY4-1", "sequence": { "sequence": "MGSGQSPSTYRIICALCKTSDETETTGPLSSKEDISAHQNCLLFSSNIYCKNSPTYDDLFGFDLEDVKKEQRRGQKLRCYFCNKTGATVGCEIKRCPRSFHYPCAIKADARAIEDFSTGTYRVYCKSHDPNPIEINDEIDNDVDLVLASVEKHVPAEQHNQSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 517, "header": "tr|A0A8M9PSY4-1|A0A8N7URD4_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X1 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0A8N7URD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0A8N7URD4-1", "sequence": { "sequence": "MGSGQSPSTYRIICALCKTSDETETTGPLSSKEDISAHQNCLLFSSNIYCKNSPTYDDLFGFDLEDVKKEQRRGQKLRCYFCNKTGATVGCEIKRCPRSFHYPCAIKADARAIEDFSTGTYRVYCKSHDPNPIEINDEIDNDVDLVLASVEKHVPAEQHNQSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESVSLSVLNKTHLRHIEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 531, "header": "tr|A0A8N7URD4-1|A0A8N7URD4_DANRE Isoform 1 of PHD finger protein 11 isoform X1 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0AB32U0C7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0AB32U0C7-1", "sequence": { "sequence": "MGSGQSPSTYRIICALCKTSDETETTGPLSSKEDISAHQNCLLFSSNIYCKNSPTYDDLFGFDLEDVKKEQRRGQKLRCYFCNKTGATVGCEIKRCPRSFHYPCAIKADARAIEDFSTGTYRVYCKSHDPNPIEIMEKHVPAEQHNQSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESVSLSVLNKTHLRHIEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 517, "header": "tr|A0AB32U0C7-1|A0A8N7URD4_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X1 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0AC58GGQ3-1", "sequence": { "sequence": "MGSGQSPSTYRIICALCKTSDETETTGPLSSKEDISAHQNCLLFSSNIYCKNSPTYDDLFGFDLEDVKKEQRRGQKLRCYFCNKTGATVGCEIKRCPRSFHYPCAIKADARAIEDFSTGTYRVYCKSHDPNPIEINDEIDNDVDLVLASVEKHVPAEQHNSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 516, "header": "tr|A0AC58GGQ3-1|A0AC58GGQ3_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X5 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0AC58GGQ4-1", "sequence": { "sequence": "MGSGQSPSTYRIICALCKTSDETETTGPLSSKEDISAHQNCLLFSSNIYCKNSPTYDDLFGFDLEDVKKEQRRGQKLRCYFCNKTGATVGCEIKRCPRSFHYPCAIKADARAIEDFSTGTYRVYCKSHDPNPIEIMEKHVPAEQHNSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESVSLSVLNKTHLRHIEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 516, "header": "tr|A0AC58GGQ4-1|A0AC58GGQ4_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X6 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0AC58GGQ6-1", "sequence": { "sequence": "MGSGQSPSTYRIICALCKTSDETETTGPLSSKEDISAHQNCLLFSSNIYCKNSPTYDDLFGFDLEDVKKEQRRGQKLRCYFCNKTGATVGCEIKRCPRSFHYPCAIKADARAIEDFSTGTYRVYCKSHDPNPIEIMEKHVPAEQHNSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 502, "header": "tr|A0AC58GGQ6-1|A0AC58GGQ6_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X8 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0AC58GGR1-1", "sequence": { "sequence": "MGSGQSPSTYRIICALCKTSDETETTGPLSSKEDISAHQNCLLFSSNIYCKNSPTYDDLFGFDLEDVKKEQRRGQKLRCYFCNKTGATVGCEIKRCPRSFHYPCAIKADARAIEDFSTGTYRVYCKSHDPNPIEIMEKHVPAEQHNQSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 503, "header": "tr|A0AC58GGR1-1|A0AC58GGR1_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X7 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGR2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0AC58GGR2-1", "sequence": { "sequence": "MEKHVPAEQHNSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESVSLSVLNKTHLRHIEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 381, "header": "tr|A0AC58GGR2-1|A0AC58GGR2_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X10 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0AC58GGR3-1", "sequence": { "sequence": "MGSGQSPSTYRIICALCKTSDETETTGPLSSKEDISAHQNCLLFSSNIYCKNSPTYDDLFGFDLEDVKKEQRRGQKLRCYFCNKTGATVGCEIKRCPRSFHYPCAIKADARAIEDFSTGTYRVYCKSHDPNPIEINDEIDNDVDLVLASVEKHVPAEQHNSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESVSLSVLNKTHLRHIEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 530, "header": "tr|A0AC58GGR3-1|A0AC58GGR3_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X2 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0AC58GGR8-1", "sequence": { "sequence": "MEKHVPAEQHNQSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 368, "header": "tr|A0AC58GGR8-1|A0AC58GGR8_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X11 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0AC58GGS0-1", "sequence": { "sequence": "MEKHVPAEQHNQSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESVSLSVLNKTHLRHIEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 382, "header": "tr|A0AC58GGS0-1|A0AC58GGS0_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X9 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGS6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0AC58GGS6-1", "sequence": { "sequence": "MAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 278, "header": "tr|A0AC58GGS6-1|A0AC58GGS6_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X14 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0AC58GGU9-1", "sequence": { "sequence": "MAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESVSLSVLNKTHLRHIEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 292, "header": "tr|A0AC58GGU9-1|A0AC58GGU9_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X13 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4/entry#A0AC58GGV4-1", "sequence": { "sequence": "MEKHVPAEQHNSTPDPERTRPSEEVKTPAKASSNGGLTSDQRSCGTADKRRIECDSQEHSPEHKTPTKKKKKRRLEYPDNENPTSADAVMAPEVSAPEESMTVNQPNHSTPLPENTRSCEKLNLSTTGAAADDEDDETDIESEESQSVLTYETDPVPCIVILDSGPSLESEISLESCSSRNPSPAHEFVTVPKQEKITPTDRTSPAQTVTPQVPAPNQKRVSDGPSVSPQHPSPTAGLRISAVCTLAQSAIKKEQLSDPPAEVSTSDSQSTVPNCQTRAAKFWTRCNQAGWSEGIFSELMSLLHSLGQRVQSGQASYQDYELAFEALKGSGQLPSIIAQIEKDLEKQEQDLQMKKAALCDAKAALAD", "length": 367, "header": "tr|A0AC58GGV4-1|A0AC58GGV4_DANRE Computationally mapped isoform of PHD finger protein 11 isoform X12 OS=Danio rerio OX=7955 GN=phf11 PE=4 SV=1 CANONICAL=A0A8N7URD4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:569187", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569187", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6H5X4-1", "protein_name": "PHD finger protein 11", "gene_name": "Phf11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQETAPPCGPVSRGDSPIIEKMEKRTCALCPEGHEWSQIYFSPSGNIVAHENCLLYSSGLVECETLDLRNTIRNFDVKSVKKEIWRGRRLKCSFCNKGGATVGCDLWFCKKSYHYVCAKKDQAILQVDGNHGTYKLFCPEHSPEQEEATESADDPSMKKKRGKNKRLSSGPPAQPKTMKCSNAKRHMTEEPHGHTDAAVKSPFLKKCQEAGLLTELFEHILENMDSVHGRLVDETASESDYEGIETLLFDCGLFKDTLRKFQEVIKSKACEWEERQRQMKQQLEALADLQQSLCSFQENGDLDCSSSTSGSLLPPEDHQVRSQESPEVQAGSGDSL", "length": 337 }, "evidence": [ { "id": "HGNC:17024", "url": "https://alliancegenome.org/gene/HGNC:17024#orthology", "database": "AGR" }, { "id": "MGI:1277133", "url": "https://alliancegenome.org/gene/MGI:1277133#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-417", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-417#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5I0E2-1", "protein_name": "PHD finger protein 11", "gene_name": "Phf11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEETAPPCGPVSTGGSLSPEKMEKRTCALCPDGHEWSVIYFAPSANIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSLCNKGGATVGCDLSSCRKSYHYVCAKKDHAIPQVDEDLGTYKIFCPEHPPQQEETTERADSPSVKKTGKKKSLSSGPPTEPKKMKFSRFKRLMKEEPHGHKDAAVKAPFLKKCLEAGLLTELFEQILEKMDSIHGRFMDETASESDYEGIKTLLFDCGLFGDILRKFQEVIKSKTCEYEERLNQMKQKLEALADLQENLCSFQECGDLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 336 }, "evidence": [ { "id": "HGNC:17024", "url": "https://alliancegenome.org/gene/HGNC:17024#orthology", "database": "AGR" }, { "id": "MGI:1277133", "url": "https://alliancegenome.org/gene/MGI:1277133#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5I0J8-1", "protein_name": "PHD finger protein 11-like", "gene_name": "Phf11l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEEPGGSNSVLNGDANSDKKMEKWTCALCPEGHDWSVIYFEPSSNIAAHENCLLYSSGLVECGPHDPRNPARSFAVKSVKKEIWRGRRLKCSFCNNKGATVGCDLQSCPKNYHLHCAKEDRAILQVDEDYGTYKLFCQRHAPGGQEPTQVDAAVKASFLKKCLEAGLLTELFEQIQQKMISIHGRFMDDTASESDYEGIKILLFDCGLFKDTLIKFEEAIKSKACECEERLNQMKQQLELLADLQQNLRSFQECGVLDPSGSTSGSLLPPEDHQCRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "RGD:11360495", "url": "https://alliancegenome.org/gene/RGD:11360495#orthology", "database": "AGR" }, { "id": "HGNC:17024", "url": "https://alliancegenome.org/gene/HGNC:17024#orthology", "database": "AGR" }, { "id": "MGI:1918441", "url": "https://alliancegenome.org/gene/MGI:1918441#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-417", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-417#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BVM9-1", "protein_name": "PHD finger protein 11A", "gene_name": "Phf11a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQEKPGCSNPVPNGDCPIIEKMEKRTCALCPEGHEWSQIYFSPSANIVAHENCLLYSSGLVECEAPDLPNTVRNFDVKSVKKEIGRGRRLKCSFCKNKGATMGYDLQSCTKNYHLSCAMEDHAILQVDEDHGTYKLFCQKHAPEGQEPTQRDAAVKAPFLKKCQEAGLLNVLLEYILEKMDLIHGRLLNETASESDYEGIETLLFGCGLFGDTLRKFQEVINSKACEWEERQRLMKQQLEALADLQQNLCSFQENGDLDCSSSTSGSLLPPEDHQVRCQESPEVQAGSGDSL", "length": 293 }, "evidence": [ { "id": "RGD:11360495", "url": "https://alliancegenome.org/gene/RGD:11360495#orthology", "database": "AGR" }, { "id": "HGNC:17024", "url": "https://alliancegenome.org/gene/HGNC:17024#orthology", "database": "AGR" }, { "id": "MGI:1918441", "url": "https://alliancegenome.org/gene/MGI:1918441#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-417", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-417#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UIL8-1", "protein_name": "PHD finger protein 11", "gene_name": "PHF11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQASPPRPERVLGASSPEARPAQEALLLPTGVFQVAEKMEKRTCALCPKDVEYNVLYFAQSENIAAHENCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGRKLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFPIIAQSAKFSGVKRKRGRKKPLSGNHVQPPETMKCNTFIRQVKEEHGRHTDATVKVPFLKKCKEAGLLNYLLEEILDKVHSIPEKLMDETTSESDYEEIGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEEIELLQDLKQTLCSFQENRDLMSSSTSISSLSY", "length": 331 }, "evidence": [ { "id": "RGD:11360495", "url": "https://alliancegenome.org/gene/RGD:11360495#orthology", "database": "AGR" }, { "id": "HGNC:17024", "url": "https://alliancegenome.org/gene/HGNC:17024#orthology", "database": "AGR" }, { "id": "MGI:1277133", "url": "https://alliancegenome.org/gene/MGI:1277133#orthology", "database": "AGR" }, { "id": "MGI:1918441", "url": "https://alliancegenome.org/gene/MGI:1918441#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-417", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-417#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URD4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URD4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 273, "end_pos": 275, "annotation": "n_glycosylation_sequon" }, { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7URD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URD4" }, { "id": "PS51805", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51805" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 11, "end_pos": 129, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 399 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 257, "end_pos": 259 }, { "start_pos": 273, "end_pos": 275 }, { "start_pos": 299, "end_pos": 301 }, { "start_pos": 83, "end_pos": 85 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVX0-1", "uniprot_ac": "A0A8N7UVX0", "uniprot_id": "A0A8N7UVX0_DANRE", "mass": { "chemical_mass": 88899.0, "monoisotopic_mass": 88899.0 }, "refseq": { "ac": "XP_005155586", "name": "cell cycle and apoptosis regulator protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155586" }, "gene_names": [ { "name": "ccar2", "type": "recommended", "evidence": [ { "id": "A0A8N7UVX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0" } ] }, { "name": "ccar2", "type": "synonym", "evidence": [ { "id": "XP_005155586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155586" } ] } ], "protein_names": [ { "name": "Cell cycle and apoptosis regulator protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UVX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0/entry#names_and_taxonomy" } ] }, { "name": "cell cycle and apoptosis regulator protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005155586", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155586" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005155586", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155586" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ccar2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-207", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-207", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000038302", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000038302", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "564155", "url": "https://www.ncbi.nlm.nih.gov/gene/564155", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025223", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025223", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025224", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025224", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564155", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564155", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WPESFPP", "url": "https://omabrowser.org/oma/group/WPESFPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVX0", "url": "https://www.orthodb.org/?gene=A0A8N7UVX0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FGT1", "url": "https://www.orthodb.org/?gene=E7FGT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14304:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14304:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14443", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14443", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14444", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14444", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005155586", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155586", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PTS0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTS0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PTS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTS0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GLC1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GLC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GLC1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GLC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FGT1", "url": "https://www.uniprot.org/uniprotkb/E7FGT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FGT1-1", "url": "https://www.uniprot.org/uniprotkb/E7FGT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-207", "url": "https://zfin.org/ZDB-GENE-091204-207", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "METQMRQRVFTGVVTQMQEHHGIVDQDVHFPMSVVVGRMPVVGEKVLVKAIQDSQKPISWTAQKVQTLNGQPFKSPPPLLPSMSSTLKPGILGTKPQPLLKSPKIPPLIPSMQPNSGGMIQLSHHQQMGWNGPFDGWGGGRKRHSEGMGGRRAGRWEDGGGGLWGGDLMHQKRKRWRATSEEEAPKKTSSAATHSVPLFSCFSRDTQACDYLELQRRYPHLHIPSSLFHLQLSWTESFPLDQPLPLRGPCLFHIGPNQPETEADVCESTDDAFAVRVLLFSMPCLEDVYSQCCNLSNDGQTQKEAVHPSTLLKFLIVDSGGEQRLPGGHWSPEADGANPAKDSLTLVNTAVRCLKEQAGLDLSACTQWYKMAELRYLSGDKVETVVVLMPDVWNLVPSEEEWASLQLEDDLSLPESPSVVFHPSAGLNLSAVSLSSLLEPQTLQTRDSCEDHLLTSVMCCRQVSLIAEMFSEMLQRDFGLQLYRCLCSLPQNISDPQTEAKQDNNTAKEEEEEIKKSDKKTTKKKDSSDARKTVKEEKDAEDAMLTDETEAVGKQPSRDGKTVSAGVEEQSSNAADNQTSKHCERPPGWTDELPRKVLLSCVFFDRQLTGSLREADLVNILLSLGLFLSPAQAQDLVKRAAVGGLCLYRNLCSRWSDSAPSDASAIAEGNKAMLPTQPCKDRGSVRRTSNTDVVNYKGKVVNLPNLLQCLESSKVAQRDLEKSVAALQSRLDAAEALQASSEQELAQQKELKRKLEKAEMINKTYEKSLKENAGQMTAVIEKMQRMVEQTTTITNANAGKEEKL", "length": 804, "header": "tr|A0A8N7UVX0-1|A0A8N7UVX0_DANRE Isoform 1 of Cell cycle and apoptosis regulator protein 2 isoform X1 OS=Danio rerio OX=7955 GN=ccar2 PE=1 SV=1 CANONICAL=A0A8N7UVX0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PTS0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0/entry#A0A8M9PTS0-1", "sequence": { "sequence": "MRQRVFTGVVTQMQEHHGIVDQDVHFPMSVVVGRMPVVGEKVLVKAIQDSQKPISWTAQKVQTLNGQPFKSPPPLLPSMSSTLKPGILGTKPQPLLKSPKIPPLIPSMQPNSGGMIQLSHHQQMGWNGPFDGWGGGRKRHSEGMGGRRAGRWEDGGGGLWGGDLMHQKRKRWRATSEEEAPKKTSSAATHSVPLFSCFSRDTQACDYLELQRRYPHLHIPSSLFHLQLSWTESFPLDQPLPLRGPCLFHIGPNQPETEADVCESTDDAFAVRVLLFSMPCLEDVYSQCCNLSNDGQTQKEAVHPSTLLKFLIVDSGGEQRLPGGHWSPEADGANPAKDSLTLVNTAVRCLKEQAGLDLSACTQWYKMAELRYLSGDKVETVVVLMPDVWNLVPSEEEWASLQLEDDLSLPESPSVVFHPSAGLNLSAVSLSSLLEPQTLQTRDSCEDHLLTSVMCCRQVSLIAEMFSEMLQRDFGLQLYRCLCSLPQNISDPQTEAKQDNNTAKEEEEEIKKSDKKTTKKKDSSDARKTVKEEKDAEDAMLTDETEAVGKQPSRDGKTVSAGVEEQSSNAADNQTSKHCERPPGWTDELPRKVLLSCVFFDRQLTGSLREADLVNILLSLGLFLSPAQAQDLVKRAAVGGLCLYRNLCSRWSDSAPSDASAIAEGNKAMLPTQPCKDRGSVRRTSNTDVVNYKGKVVNLPNLLQCLESSKVAQRDLEKSVAALQSRLDAAEALQASSEQELAQQKELKRKLEKAEMINKTYEKSLKENAGQMTAVIEKMQRMVEQTTTITNANAGKEEKL", "length": 800, "header": "tr|A0A8M9PTS0-1|A0A8N7UVX0_DANRE Computationally mapped isoform of Cell cycle and apoptosis regulator protein 2 isoform X1 OS=Danio rerio OX=7955 GN=ccar2 PE=1 SV=1 CANONICAL=A0A8N7UVX0-1" }, "locus": {} }, { "isoform_ac": "A0A8N7UVX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0/entry#A0A8N7UVX0-1", "sequence": { "sequence": "METQMRQRVFTGVVTQMQEHHGIVDQDVHFPMSVVVGRMPVVGEKVLVKAIQDSQKPISWTAQKVQTLNGQPFKSPPPLLPSMSSTLKPGILGTKPQPLLKSPKIPPLIPSMQPNSGGMIQLSHHQQMGWNGPFDGWGGGRKRHSEGMGGRRAGRWEDGGGGLWGGDLMHQKRKRWRATSEEEAPKKTSSAATHSVPLFSCFSRDTQACDYLELQRRYPHLHIPSSLFHLQLSWTESFPLDQPLPLRGPCLFHIGPNQPETEADVCESTDDAFAVRVLLFSMPCLEDVYSQCCNLSNDGQTQKEAVHPSTLLKFLIVDSGGEQRLPGGHWSPEADGANPAKDSLTLVNTAVRCLKEQAGLDLSACTQWYKMAELRYLSGDKVETVVVLMPDVWNLVPSEEEWASLQLEDDLSLPESPSVVFHPSAGLNLSAVSLSSLLEPQTLQTRDSCEDHLLTSVMCCRQVSLIAEMFSEMLQRDFGLQLYRCLCSLPQNISDPQTEAKQDNNTAKEEEEEIKKSDKKTTKKKDSSDARKTVKEEKDAEDAMLTDETEAVGKQPSRDGKTVSAGVEEQSSNAADNQTSKHCERPPGWTDELPRKVLLSCVFFDRQLTGSLREADLVNILLSLGLFLSPAQAQDLVKRAAVGGLCLYRNLCSRWSDSAPSDASAIAEGNKAMLPTQPCKDRGSVRRTSNTDVVNYKGKVVNLPNLLQCLESSKVAQRDLEKSVAALQSRLDAAEALQASSEQELAQQKELKRKLEKAEMINKTYEKSLKENAGQMTAVIEKMQRMVEQTTTITNANAGKEEKL", "length": 804, "header": "tr|A0A8N7UVX0-1|A0A8N7UVX0_DANRE Isoform 1 of Cell cycle and apoptosis regulator protein 2 isoform X1 OS=Danio rerio OX=7955 GN=ccar2 PE=1 SV=1 CANONICAL=A0A8N7UVX0-1" }, "locus": {} }, { "isoform_ac": "A0AC58GLC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0/entry#A0AC58GLC1-1", "sequence": { "sequence": "MRQRVFTGVVTQMQEHHGIVDQDVHFPMSVVVGRMPVVGEKVLVKAIQDSQKPISWTAQKVQTLNGQPFKSPPPLLPSMSSTLKPGILGTKPQPLLKSPKIPPLIPSMQPNSGGMIQLSHHQQMGWNGPFDGWGGGRKRHSEGMGGRRAGRWEDGGGGLWGGDLMHQKRKRWRATSEEEAPKKTSSAATHSVPLFSCFSRDTQACDYLELQRRYPHLHIPSSLFHLQLSWTESFPLDQPLPLRGPCLFHIGPNQPETEADVCESTDDAFAVRVLLFSMPCLEDVYSQCCNLSNDGQTQKEAVHPSTLLKFLIVDSGGEQRLPGGHWSPEADGANPAKDSLTLVNTAVRCLKEQAGLDLSACTQWYKMAELRYLSGDKVETVVVLMPDVWNLVPSEEEWASLQLEDDLSLPESPSVVFHPSAGLNLSAVSLSSLLEPQTLQTRDSCEVSLIAEMFSEMLQRDFGLQLYRCLCSLPQNISDPQTEAKQDNNTAKEEEEEIKKSDKKTTKKKDSSDARKTVKEEKDAEDAMLTDETEAVGKQPSRDGKTVSAGVEEQSSNAADNQTSKHCERPPGWTDELPRKVLLSCVFFDRQLTGSLREADLVNILLSLGLFLSPAQAQDLVKRAAVGGLCLYRNLCSRWSDSAPSDASAIAEGNKAMLPTQPCKDRGSVRRTSNTDVVNYKGKVVNLPNLLQCLESSKVAQRDLEKSVAALQSRLDAAEALQASSEQELAQQKELKRKLEKAEMINKTYEKSLKENAGQMTAVIEKMQRMVEQTTTITNANAGKEEKL", "length": 788, "header": "tr|A0AC58GLC1-1|A0AC58GLC1_DANRE Computationally mapped isoform of Cell cycle and apoptosis regulator protein 2 isoform X4 OS=Danio rerio OX=7955 GN=ccar2 PE=1 SV=1 CANONICAL=A0A8N7UVX0-1" }, "locus": {} }, { "isoform_ac": "E7FGT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0/entry#E7FGT1-1", "sequence": { "sequence": "METQMRQRVFTGVVTQMQEHHGIVDQDVHFPMSVVVGRMPVVGEKVLVKAIQDSQKPISWTAQKVQTLNGQPFKSPPPLLPSMSSTLKPGILGTKPQPLLKSPKIPPLIPSMQPNSGGMIQLSHHQQMGWNGPFDGWGGGRKRHSEGMGGRRAGRWEDGGGGLWGGDLMHQKRKRWRATSEEEAPKKTSSAATHSVPLFSCFSRDTQACDYLELQRRYPHLHIPSSLFHLQLSWTESFPLDQPLPLRGPCLFHIGPNQPETEADVCESTDDAFAVRVLLFSMPCLEDVYSQCCNLSNDGQTQKEAVHPSTLLKFLIVDSGGEQRLPGGHWSPEADGANPAKDSLTLVNTAVRCLKEQAGLDLSACTQWYKMAELRYLSGDKVETVVVLMPDVWNLVPSEEEWASLQLEDDLSLPESPSVVFHPSAGLNLSAVSLSSLLEPQTLQTRDSCEVSLIAEMFSEMLQRDFGLQLYRCLCSLPQNISDPQTEAKQDNNTAKEEEEEIKKSDKKTTKKKDSSDARKTVKEEKDAEDAMLTDETEAVGKQPSRDGKTVSAGVEEQSSNAADNQTSKHCERPPGWTDELPRKVLLSCVFFDRQLTGSLREADLVNILLSLGLFLSPAQAQDLVKRAAVGGLCLYRNLCSRWSDSAPSDASAIAEGNKAMLPTQPCKDRGSVRRTSNTDVVNYKGKVVNLPNLLQCLESSKVAQRDLEKSVAALQSRLDAAEALQASSEQELAQQKELKRKLEKAEMINKTYEKSLKENAGQMTAVIEKMQRMVEQTTTITNANAGKEEKL", "length": 792, "header": "tr|E7FGT1-1|E7FGT1_DANRE Computationally mapped isoform of Cell cycle and apoptosis regulator protein 2 isoform X3 OS=Danio rerio OX=7955 GN=ccar2 PE=1 SV=2 CANONICAL=A0A8N7UVX0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:564155", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564155", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LM55-1", "protein_name": "Cell cycle and apoptosis regulator 2", "gene_name": "Ccar2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQFKRQRINPLPGGRNFSGAASTSLLGPPPGLLTPPVATDLSQNARHLQSGEKQRVFTGIVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQPLLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNRFPARGPHGRLDQGRSDDYDSKKRKQRAGGEPWGAKKPRHDLPPYRVHLTPYAVDSPTCDFLELQRRYRSLLVPSDFLSVHLSWLSAFPLGQPFSLHHPSRIQVSSEKEAAPDTGAEPSPEDSDPTYSSKVLLLSSPGLEEFYRCCMLFVDDMAEPRETPEHPLKQLKFLLGRKEEEAVLVGGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSTCTKWWRFAEFQYLQPGPPRQLHTVVVYLPDVWTIMPTLEEWEALCQQKATEAAPQPQEASGEAEATEQAPDVSEQADTSKQDTETAEATTQQDVDTELPEAPPPPLEPAVMARPGCVNLSLYGIVEDRRPKERISFEVVVLAELFVEMLQRDFGYRIYKVLLSLPEKVVSPPEPEKEEAAKEDVVKEEEAVKEEAVKVSKDEVQNEGTAAEADSPLKEDGLLPKQPSAGGEEEEKARGEAAEDLCEMALDPDLLLLRDDGEEEFAGAKLEETEVRSVASNQSEMEYSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVAQNICQYRSLQYSRAEALDDGLPEDVLFGNLDLLPPSGKSTKPGAAPTEHKGLVPHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRARLAEAEETARTVERQKNQLQRQMQDFRRRLTPLHLEMQRIVEKADSWVEKEEPTPSN", "length": 922 }, "evidence": [ { "id": "HGNC:23360", "url": "https://alliancegenome.org/gene/HGNC:23360#orthology", "database": "AGR" }, { "id": "MGI:2444228", "url": "https://alliancegenome.org/gene/MGI:2444228#orthology", "database": "AGR" }, { "id": "RGD:1309922", "url": "https://alliancegenome.org/gene/RGD:1309922#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-207", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-207#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N163-1", "protein_name": "Cell cycle and apoptosis regulator protein 2", "gene_name": "CCAR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQFKRQRINPLPGGRNFSGTASTSLLGPPPGLLTPPVATELSQNARHLQGGEKQRVFTGIVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQPLLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNRFPARGPHGRLDQGRSDDYDSKKRKQRAGGEPWGAKKPRHDLPPYRVHLTPYTVDSPICDFLELQRRYRSLLVPSDFLSVHLSWLSAFPLSQPFSLHHPSRIQVSSEKEAAPDAGAEPITADSDPAYSSKVLLLSSPGLEELYRCCMLFVDDMAEPRETPEHPLKQIKFLLGRKEEEAVLVGGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSGCTKWWRFAEFQYLQPGPPRRLQTVVVYLPDVWTIMPTLEEWEALCQQKAAEAAPPTQEAQGETEPTEQAPDALEQAADTSRRNAETPEATTQQETDTDLPEAPPPPLEPAVIARPGCVNLSLHGIVEDRRPKERISFEVMVLAELFLEMLQRDFGYRVYKMLLSLPEKVVSPPEPEKEEAAKEEATKEEEAIKEEVVKEPKDEAQNEGPATESEAPLKEDGLLPKPLSSGGEEEEKPRGEASEDLCEMALDPELLLLRDDGEEEFAGAKLEDSEVRSVASNQSEMEFSSLQDMPKELDPSAVLPLDCLLAFVFFDANWCGYLHRRDLERILLTLGIRLSAEQAKQLVSRVVTQNICQYRSLQYSRQEGLDGGLPEEVLFGNLDLLPPPGKSTKPGAAPTEHKALVSHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRVRLAEAEETARTAERQKSQLQRLLQELRRRLTPLQLEIQRVVEKADSWVEKEEPAPSN", "length": 923 }, "evidence": [ { "id": "HGNC:23360", "url": "https://alliancegenome.org/gene/HGNC:23360#orthology", "database": "AGR" }, { "id": "MGI:2444228", "url": "https://alliancegenome.org/gene/MGI:2444228#orthology", "database": "AGR" }, { "id": "RGD:1309922", "url": "https://alliancegenome.org/gene/RGD:1309922#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-207", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-207#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VDP4-1", "protein_name": "Cell cycle and apoptosis regulator protein 2", "gene_name": "Ccar2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQFKRQRINPLPGGRNFSGAASTSLLGPPPGLLTPPVATDLSQNARHLQSGEKQRVFTGIVTSLHDYFGVVDEEVFFQLSVVKGRLPQLGEKVLVKAAYNPGQAVPWNAVKVQTLSNQPLLKSPAPPLLHVAALGQKQGILGAQPQLIFQPHRIPPLFPQKPLSLFQTSHTLHLSHLNRFPARGPHGRLDQGRSDDYDSKKRKQRAGGEPWGAKKPRHDLSPYRVHLTPYTVDSPTCDFLELQRRYRSLLVPSDFLSVHLSWLSAFPLGQPFSLHHPSRIQVSSEKEAAPDTGAEPSPEDSDPTYSSKVLLLSSPGLEEFYRCCMLFVDDMAEPRETPEHPLKQLKFLLGRKEEEAVLVGGEWSPSLDGLDPQADPQVLVRTAIRCAQAQTGIDLSTCTKWWRFAEFQYLQPGPPRQLHTVVVYLPDVWTIMPTLEEWEALCQQKATEAAPQPHEASGEAEATEQAPDVSEQADTSKQNTETMEATTQQDVDTDLPEAPPPPLEPAVMARPRCVNLSLYGIVEDRRPKERISFEVVVLAELFVEMLQRDFGYRIYKTLLSLPEKVVSPPEPEKEEAAKEDAVKEEEAVKEEAVKVSKDEVQNEGTAAESDSPLKEDGLLPKRPSSGGEEEEKARGEAAEDLCEMALDPDLLLLRDDGEDEFAGAKLEETEVRSVASNQSEMEYSSLQDMPKELDPSTVLPLDCLLAFVFFDANWCGYLHRRDLERVLLTLGIRLSAEQAKQLVSRVVAQNICQYRSLQYSRAEVLDDGLPEDVLFGNLDLLPPSGKSTKPGAAPTEHKGLVPHNGSLINVGSLLQRAEQQDSGRLYLENKIHTLELKLEESHNRFSATEVTNKTLAAEMQELRARLAEAEETARTAERQKNQLQRQMQDFRRRLTPLHLEMQRIVEKADSWVEKEEPTPSN", "length": 922 }, "evidence": [ { "id": "HGNC:23360", "url": "https://alliancegenome.org/gene/HGNC:23360#orthology", "database": "AGR" }, { "id": "MGI:2444228", "url": "https://alliancegenome.org/gene/MGI:2444228#orthology", "database": "AGR" }, { "id": "RGD:1309922", "url": "https://alliancegenome.org/gene/RGD:1309922#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-207", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-207#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 504, "end_pos": 506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UVX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX0" }, { "id": "SM01122", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01122" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DBC1/CARP1 catalytically inactive NUDIX hydrolase", "eco_id": "ECO_0000259", "start_pos": 305, "end_pos": 425, "start_aa": "Ala", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 294, "end_pos": 296 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 492, "end_pos": 494 }, { "start_pos": 504, "end_pos": 506 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 762, "end_pos": 764 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { 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The reference sequence was derived from CR382323.8. On Nov 2, 2007 this sequence version replaced XP_001341361.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001103696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103696" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUM2", "url": "https://www.uniprot.org/uniprotkb/A5WUM2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100001344", "url": "https://www.uniprot.org/uniprotkb/A5WUM2", "locus": {} } ], "crossref": [ { "id": "cd05516", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05516", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100001344", "url": "https://www.ncbi.nlm.nih.gov/gene/100001344", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001487", "url": 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"Protein Classification" ] }, { "id": "PTHR16062:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16062:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00439", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00439", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001103696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103696", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9QDF0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QDF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QDF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WUM2", "url": "https://www.uniprot.org/uniprotkb/A5WUM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WUM2-1", "url": "https://www.uniprot.org/uniprotkb/A5WUM2-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRLAARCNAGLLILSPPDWSQPGDHSQSQAIHNGVSEVMEEESNLKKRKSEQQGNQGSETGQEGVEKVKKRRGRPPAEKLPPNPPKLTKQMNTIVDMVINYKDTLGRQISKGFVQLPSRKEVPEYYELIRKPVDFRRIRERVRNHKYRCIADLEKDIMQMCHNAQTFNLEGSQIFEDSIVLKSVFESARQRIVELSEEDNDAVGSSEADGSHHLDIEAPVSETTNPRLDEKKEKNQTAPSNSSSKEVAHSDEDIGKDCGNTTRGLFN", "length": 268, "header": "tr|A5WUM2-1|A5WUM2_DANRE Isoform 1 of Uncharacterized protein LOC100001344 OS=Danio rerio OX=7955 GN=LOC100001344 PE=4 SV=1 CANONICAL=A5WUM2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9QDF0-1", "url": "https://www.uniprot.org/uniprotkb/A5WUM2/entry#A0A8M9QDF0-1", "sequence": { "sequence": "MEEESNLKKRKSEQQGNQGSETGQEGVEKVKKRRGRPPAEKLPPNPPKLTKQMNTIVDMVINYKDTLGRQISKGFVQLPSRKEVPEYYELIRKPVDFRRIRERVRNHKYRCIADLEKDIMQMCHNAQTFNLEGSQIFEDSIVLKSVFESARQRIVELSEEDNDAVGSSEADGSHHLDIKAPVSETTNPRLDEKKEKNQTAPSNSSSKEVAHSDEDIGKDCGNTTRGLFN", "length": 229, "header": "tr|A0A8M9QDF0-1|A5WUM2_DANRE Computationally mapped isoform of Uncharacterized protein LOC100001344 OS=Danio rerio OX=7955 GN=LOC100001344 PE=4 SV=1 CANONICAL=A5WUM2-1" }, "locus": {} }, { "isoform_ac": "A5WUM2-1", "url": "https://www.uniprot.org/uniprotkb/A5WUM2/entry#A5WUM2-1", "sequence": { "sequence": "MKRLAARCNAGLLILSPPDWSQPGDHSQSQAIHNGVSEVMEEESNLKKRKSEQQGNQGSETGQEGVEKVKKRRGRPPAEKLPPNPPKLTKQMNTIVDMVINYKDTLGRQISKGFVQLPSRKEVPEYYELIRKPVDFRRIRERVRNHKYRCIADLEKDIMQMCHNAQTFNLEGSQIFEDSIVLKSVFESARQRIVELSEEDNDAVGSSEADGSHHLDIEAPVSETTNPRLDEKKEKNQTAPSNSSSKEVAHSDEDIGKDCGNTTRGLFN", "length": 268, "header": "tr|A5WUM2-1|A5WUM2_DANRE Isoform 1 of Uncharacterized protein LOC100001344 OS=Danio rerio OX=7955 GN=LOC100001344 PE=4 SV=1 CANONICAL=A5WUM2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, 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{ "database": "UniProtKB", "id": "A5WUM2", "url": "https://www.uniprot.org/uniprotkb/A5WUM2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "RSC-type complex", "id": "GO:0016586", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016586", "evidence": [ { "database": "UniProtKB", "id": "A5WUM2", "url": "https://www.uniprot.org/uniprotkb/A5WUM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5WUM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM2" }, { "id": "PS50014", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50014" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Bromo", "eco_id": "ECO_0000259", "start_pos": 106, "end_pos": 176, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 236, "end_pos": 238 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 261, "end_pos": 263 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8N7UTG6-1", "uniprot_ac": "A0A8N7UTG6", "uniprot_id": "A0A8N7UTG6_DANRE", "mass": { "chemical_mass": 45066.0, "monoisotopic_mass": 45066.0 }, "refseq": { "ac": "XP_698622", "name": "GTPase IMAP family member 8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698622" }, "gene_names": [ { "name": "si:ch211-139n6.3", "type": "recommended", "evidence": [ { "id": "A0A8N7UTG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTG6" } ] }, { "name": "si:ch211-139n6.3", "type": "synonym", "evidence": [ { "id": "XP_698622", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698622" } ] } ], "protein_names": [ { "name": "GTPase IMAP family member 8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_698622", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698622" }, { "id": "A0A8N7UTG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTG6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_698622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698622" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UTG6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTG6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-139n6.3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTG6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041111-114", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041111-114", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UTG6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UTG6", "database": "AlphaFoldDB", "categories": [] }, { "id": "570095", "url": "https://www.ncbi.nlm.nih.gov/gene/570095", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006703", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006703", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570095", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570095", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z344", "url": "https://www.orthodb.org/?gene=A0A8M6Z344", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UTG6", "url": "https://www.orthodb.org/?gene=A0A8N7UTG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10903", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10903:SF186", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903:SF186", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04548", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04548", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_698622", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698622", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z344", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z344", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z344-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z344-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QLB2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QLB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QLB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UTG6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UTG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041111-114", "url": "https://zfin.org/ZDB-GENE-041111-114", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPKGEHKSAGDVSADDSVVTVVLLGQNSTDKCLVGNTMLAFKCFQPGQRMYQKALGRVGNELLYIINTPEFFWSPNQDPETNAIEAMKPSYPGSRMFLLVLQNKQLSNEEMEMFTKLKERFGEKIVENITVVLIDSKESSEVSRDTANASLKQILHECNERMCVFSKDMRGVDLVGQLLPEKPDEDLDRSNVDNNKQINPEEKDKSEQPKPMQEESMTIQPSGGEGMTTMVLLGLNSDDKCLIGNSILQHDCFTPGRTICDRVVARVGDQMVCIVNTPDLFVFKPRPDLIADSMEEMQPTYTGPRVFLMVLQDKTLTHEEMEMIADLIEKFGEKLLKNMLAVLIGSKDDKSEKCEIEENLKMFLDECKENIYVYRSDVKSTDLVEQLMGKGKTQESEKN", "length": 399, "header": "tr|A0A8N7UTG6-1|A0A8N7UTG6_DANRE Isoform 1 of GTPase IMAP family member 8 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-139n6.3 PE=3 SV=1 CANONICAL=A0A8N7UTG6-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z344-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTG6/entry#A0A8M6Z344-1", "sequence": { "sequence": "MPKGEHKSAGDVSADDSVVTVVLLGQNSTDKCLVGNTMLAFKCFQPGQRMYQKALGRVGNELLYIINTPEFFWSPNQDPETNAIEAMKPSYPGSRMFLLVLQNKQLSNEEMEMFTKLKERFGEKIVENITVVLIDSKESSEVSRDTANASLKQILHECNERMCVFSKDMRGVDLVGQLLPEKPDEDLDRSNVDNNKQINPEEKDKSEQPKPMQEESMTIQPSGGEGMTTMVLLGLNSDDKCLIGNSILQHDCFTPGRTICDRVVARVGDQMVCIVNTPDLFVFKPRPDLIADSMEEMQPTYTGPRVFLMKDKQKRNKTQLHTYQNGPLHQSKFKINVNNFTHTHTHTNTKHIKFST", "length": 356, "header": "tr|A0A8M6Z344-1|A0A8N7UTG6_DANRE Computationally mapped isoform of GTPase IMAP family member 8 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-139n6.3 PE=3 SV=1 CANONICAL=A0A8N7UTG6-1" }, "locus": {} }, { "isoform_ac": "A0A8M9QLB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTG6/entry#A0A8M9QLB2-1", "sequence": { "sequence": "MPKGEHKSAGDVSADDSVVTVVLLGQNSTDKCLVGNTMLAFKCFQPGQRMYQKALGRVGNELLYIINTPEFFWSPNQDPETNAIEAMKPSYPGSRMFLLVLQNKQLSNEEMEMFTKLKERFGEKIVENITVVLIDSKESSEVSRDTANASLKQILHECNERMCVFSKDMRGVDLVGQLLPEKPDEDLDRSNVDNNKQINPEEKDKSEQPKPMQEESMTIQPSGGEGMTTMVLLGLNSDDKCLIGNSILQHDCFTPGRTICDRVVARVGDQMVCIVNTPDLFVFKPRPDLIADSMEEMQPTYTGPRVFLMKDKQKRNKTQLHTYQNGPLHQT", "length": 331, "header": "tr|A0A8M9QLB2-1|A0A8N7UTG6_DANRE Computationally mapped isoform of GTPase IMAP family member 8 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-139n6.3 PE=3 SV=1 CANONICAL=A0A8N7UTG6-1" }, "locus": {} }, { "isoform_ac": "A0A8N7UTG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTG6/entry#A0A8N7UTG6-1", "sequence": { "sequence": "MPKGEHKSAGDVSADDSVVTVVLLGQNSTDKCLVGNTMLAFKCFQPGQRMYQKALGRVGNELLYIINTPEFFWSPNQDPETNAIEAMKPSYPGSRMFLLVLQNKQLSNEEMEMFTKLKERFGEKIVENITVVLIDSKESSEVSRDTANASLKQILHECNERMCVFSKDMRGVDLVGQLLPEKPDEDLDRSNVDNNKQINPEEKDKSEQPKPMQEESMTIQPSGGEGMTTMVLLGLNSDDKCLIGNSILQHDCFTPGRTICDRVVARVGDQMVCIVNTPDLFVFKPRPDLIADSMEEMQPTYTGPRVFLMVLQDKTLTHEEMEMIADLIEKFGEKLLKNMLAVLIGSKDDKSEKCEIEENLKMFLDECKENIYVYRSDVKSTDLVEQLMGKGKTQESEKN", "length": 399, "header": "tr|A0A8N7UTG6-1|A0A8N7UTG6_DANRE Isoform 1 of GTPase IMAP family member 8 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-139n6.3 PE=3 SV=1 CANONICAL=A0A8N7UTG6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:570095", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570095", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UTG6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTG6" } ], "pmid": "" }, { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UTG6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTG6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UTG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTG6" }, { "id": "PF04548", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04548" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AIG1-type G", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 167, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 }, { "start_pos": 148, "end_pos": 150 }, { "start_pos": 27, "end_pos": 29 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UUM9-1", "uniprot_ac": "A0A8N7UUM9", "uniprot_id": "A0A8N7UUM9_DANRE", "mass": { "chemical_mass": 182426.0, "monoisotopic_mass": 182426.0 }, "refseq": { "ac": "XP_684050", "name": "uncharacterized protein wu:fc17b08 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684050" }, "gene_names": [ { "name": "wu:fc17b08", "type": "synonym", "evidence": [ { "id": "XP_684050", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684050" }, { "id": "A0A8N7UUM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUM9" } ] } ], "protein_names": [ { "name": "Uncharacterized protein wu:fc17b08 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UUM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUM9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein wu:fc17b08 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_684050", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684050" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_684050.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_684050", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684050" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUM9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUM9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUM9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-2746", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2746", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUM9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UUM9", "database": "AlphaFoldDB", "categories": [] }, { "id": "556205", "url": "https://www.ncbi.nlm.nih.gov/gene/556205", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028104", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028104", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556205", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556205", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UUM9", "url": "https://www.orthodb.org/?gene=A0A8N7UUM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14931", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14931", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14931:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14931:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15090", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15090", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_684050", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684050", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9QNK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QNK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QNK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QNK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUM9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-2746", "url": "https://zfin.org/ZDB-GENE-030131-2746", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MANLATKRLCTNERFPVRQDSDCWRSKLIRSVGLDRISDLLLRTQILDDLRLLKDCKPASVSHSSFDEKCLFCCLRREKVKEHITALNKQIVESGGKPLLGKDPSNISRLEWQSDEFLSAVLHRNEYTPRIPDPHIPVVACGVMQQMLSKLTTYYTSRNSCSQDSLQTNGKKDQSLVKTSRVSSSAAVGALSAQNKFIMVDQDAPLDLSVKKIKVEDIQQDGVLDLSTKKNLSKDHLCLKNSPVHVSPAARLVKRDSIDLSLAQVGDLQSASTLEQFMSKLCLHHQHQIVDALGFLQSEVKTVSNHFQTPISTLPEKQATTSSSIVSSESRSEVQRPERTCSVDAALSIKTQSVARSQKTTSEDLNADVSSIATSEKTVDICKKEDFSSSSSCGTVVELENASSPVTKTTTDHQEIKKSLVSSLQQVKHGDSVKKCLCSAERCTCTAASDQEDLLSKHTDMSSVAQNEDAVVNPSTVHKASNVVLSVSPRTARKSRKGSCLRPRNGSLSCIISDPDSHCDLVYIKKSIIECQPQSRNRLHPRLNARKSTRGHKYVEEYLELKTVRTLARKPIHDSVGNCPVLLADLQTSVTPRQTLSGSVPLVNAPFTGDCMKNIIQKLSSEQIAEEEMPGDVVKVTGISLMVETSHTDKTETNSQISHEPSCKESEASMQIDVSLETVSCTPNAVEQEENMDVEEAKESTETTELAVETEQCDPPLVPIEEEQCDPPVVPIKEIQCNPSVVPIEKEVDCGTESKPECEGQSLEPSLSPASSNMDPESSTIEISDEQNNERESTSPTDAETDTADVQEPSEASEVNANTEEDRNAQEQTLGDVEPNLQMLPEKKEEDLSGSKIAEVSTVQALANCKKDTDSIPPKVLSTKHTVSSDRCLRSRVSKASVDVVKDSVKHGASEPVDHANDANTKTQSAETDVCTGEEHNSEPVEIPIEKPNHPVIDNAVKTTPKSKGGKAKQQSPKVEMNEPPSVLPPEVLPETISTASNTTESEKQHKMNSQASENLTLRSKSSPIELPVSGDCSPNKKSPHSSENMLLRSRSNTEKICGSKSNSLTDGHSETQGQTPLRENSSTSDQGSIGDLCTPSESATRMPLRSRTISTNKQTVTRESPVKCSIKSEPASSPSSKKIEANGHMPLRSSAGVTAEQPCNDKSALESPGRMSLRRGNASNTEKPCGSTTPPTANKRPSRIHKVSASSSGDAEEIPSSSKLEIQNKKHTESQIKGSDEFFHVPSLPRSEPIVCNPSKFLEALRGEEHQQLISNLNAKFDKMQKGWVQMDKEGQPAPKHKNKADRLKEIWKSKRRVRKSRPLEQQKFSPVQMLFMKPFDLTSICRWFLQSTETKSLVIVKKVNTRLPSETQLCFHSSSAGAGSANGIFPSLQAERLKKHLKKFAIASPVKSNPKNQRLISKALGQGISLMSKEKPKPTTATRICTKAQSLAGVTPVQVPESISATAGSAKNPASARILRKYSNMREKLQVQQNKKCKEKALKSAGLKATIIPKKDDKEKLQTQKGPKSVVVKKISSLSKTAKANSVLKERALKSEDGSSTKRLQGLKRITQAIGAHASANKLSKKLVRTDKAQRVKSIKVDSKKSALQKIPPEPQTLDVDSKSSEDQVLTRSQRKMEGAPSQTASPKSTMKRGLEPLVTPTKRTRTSKP", "length": 1668, "header": "tr|A0A8N7UUM9-1|A0A8N7UUM9_DANRE Isoform 1 of Uncharacterized protein wu:fc17b08 isoform X1 OS=Danio rerio OX=7955 GN= PE=1 SV=1 CANONICAL=A0A8N7UUM9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9QNK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUM9/entry#A0A8M9QNK6-1", "sequence": { "sequence": "MQQMLSKLTTYYTSRNSCSQDSLQTNGKKDQSLVKTSRVSSSAAVGALSAQNKFIMVDQDAPLDLSVKKIKVEDIQQDGVLDLSTKKNLSKDHLCLKNSPVHVSPAARLVKRDSIDLSLAQVGDLQSASTLEQFMSKLCLHHQHQIVDALGFLQSEVKTVSNHFQTPISTLPEKQATTSSSIVSSESRSEVQRPERTCSVDAALSIKTQSVARSQKTTSEDLNADVSSIATSEKTVDICKKEDFSSSSSCGTVVELENASSPVTKTTTDHQEIKKSLVSSLQQVKHGDSVKKCLCSAERCTCTAASDQEDLLSKHTDMSSVAQNEDAVVNPSTVHKASNVVLSVSPRTARKSRKGSCLRPRNGSLSCIISDPDSHCDLVYIKKSIIECQPQSRNRLHPRLNARKSTRGHKYVEEYLELKTVRTLARKPIHDSVGNCPVLLADLQTSVTPRQTLSGSVPLVNAPFTGDCMKNIIQKLSSEQIAEEEMPGDVVKVTGISLMVETSHTDKTETNSQISHEPSCKESEASMQIDVSLETVSCTPNAVEQEENMDVEEAKESTETTELAVETEQCDPPLVPIEEEQCDPPVVPIKEIQCNPSVVPIEKEVDCGTESKPECEGQSLEPSLSPASSNMDPESSTIEISDEQNNERESTSPTDAETDTADVQEPSEASEVNANTEEDRNAQEQTLGDVEPNLQMLPEKKEEDLSGSKIAEVSTVQALANCKKDTDSIPPKVLSTKHTVSSDRCLRSRVSKASVDVVKDSVKHGASEPVDHANDANTKTQSAETDVCTGEEHNSEPVEIPIEKPNHPVIDNAVKTTPKSKGGKAKQQSPKVEMNEPPSVLPPEVLPETISTASNTTESEKQHKMNSQASENLTLRSKSSPIELPVSGDCSPNKKSPHSSENMLLRSRSNTEKICGSKSNSLTDGHSETQGQTPLRENSSTSDQGSIGDLCTPSESATRMPLRSRTISTNKQTVTRESPVKCSIKSEPASSPSSKKIEANGHMPLRSSAGVTAEQPCNDKSALESPGRMSLRRGNASNTEKPCGSTTPPTANKRPSRIHKVSASSSGDAEEIPSSSKLEIQNKKHTESQIKGSDEFFHVPSLPRSEPIVCNPSKFLEALRGEEHQQLISNLNAKFDKMQKGWVQMDKEGQPAPKHKNKADRLKEIWKSKRRVRKSRPLEQQKFSPVQMLFMKPFDLTSICRWFLQSTETKSLVIVKKVNTRLPSETQLCFHSSSAGAGSANGIFPSLQAERLKKHLKKFAIASPVKSNPKNQRLISKALGQGISLMSKEKPKPTTATRICTKAQSLAGVTPVQVPESISATAGSAKNPASARILRKYSNMREKLQVQQNKKCKEKALKSAGLKATIIPKKDDKEKLQTQKGPKSVVVKKISSLSKTAKANSVLKERALKSEDGSSTKRLQGLKRITQAIGAHASANKLSKKLVRTDKAQRVKSIKVDSKKSALQKIPPEPQTLDVDSKSSEDQVLTRSQRKMEGAPSQTASPKSTMKRGLEPLVTPTKRTRTSKP", "length": 1525, "header": "tr|A0A8M9QNK6-1|A0A8N7UUM9_DANRE Computationally mapped isoform of Uncharacterized protein wu:fc17b08 isoform X1 OS=Danio rerio OX=7955 GN= PE=1 SV=1 CANONICAL=A0A8N7UUM9-1" }, "locus": {} }, { "isoform_ac": "A0A8N7UUM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUM9/entry#A0A8N7UUM9-1", "sequence": { "sequence": "MANLATKRLCTNERFPVRQDSDCWRSKLIRSVGLDRISDLLLRTQILDDLRLLKDCKPASVSHSSFDEKCLFCCLRREKVKEHITALNKQIVESGGKPLLGKDPSNISRLEWQSDEFLSAVLHRNEYTPRIPDPHIPVVACGVMQQMLSKLTTYYTSRNSCSQDSLQTNGKKDQSLVKTSRVSSSAAVGALSAQNKFIMVDQDAPLDLSVKKIKVEDIQQDGVLDLSTKKNLSKDHLCLKNSPVHVSPAARLVKRDSIDLSLAQVGDLQSASTLEQFMSKLCLHHQHQIVDALGFLQSEVKTVSNHFQTPISTLPEKQATTSSSIVSSESRSEVQRPERTCSVDAALSIKTQSVARSQKTTSEDLNADVSSIATSEKTVDICKKEDFSSSSSCGTVVELENASSPVTKTTTDHQEIKKSLVSSLQQVKHGDSVKKCLCSAERCTCTAASDQEDLLSKHTDMSSVAQNEDAVVNPSTVHKASNVVLSVSPRTARKSRKGSCLRPRNGSLSCIISDPDSHCDLVYIKKSIIECQPQSRNRLHPRLNARKSTRGHKYVEEYLELKTVRTLARKPIHDSVGNCPVLLADLQTSVTPRQTLSGSVPLVNAPFTGDCMKNIIQKLSSEQIAEEEMPGDVVKVTGISLMVETSHTDKTETNSQISHEPSCKESEASMQIDVSLETVSCTPNAVEQEENMDVEEAKESTETTELAVETEQCDPPLVPIEEEQCDPPVVPIKEIQCNPSVVPIEKEVDCGTESKPECEGQSLEPSLSPASSNMDPESSTIEISDEQNNERESTSPTDAETDTADVQEPSEASEVNANTEEDRNAQEQTLGDVEPNLQMLPEKKEEDLSGSKIAEVSTVQALANCKKDTDSIPPKVLSTKHTVSSDRCLRSRVSKASVDVVKDSVKHGASEPVDHANDANTKTQSAETDVCTGEEHNSEPVEIPIEKPNHPVIDNAVKTTPKSKGGKAKQQSPKVEMNEPPSVLPPEVLPETISTASNTTESEKQHKMNSQASENLTLRSKSSPIELPVSGDCSPNKKSPHSSENMLLRSRSNTEKICGSKSNSLTDGHSETQGQTPLRENSSTSDQGSIGDLCTPSESATRMPLRSRTISTNKQTVTRESPVKCSIKSEPASSPSSKKIEANGHMPLRSSAGVTAEQPCNDKSALESPGRMSLRRGNASNTEKPCGSTTPPTANKRPSRIHKVSASSSGDAEEIPSSSKLEIQNKKHTESQIKGSDEFFHVPSLPRSEPIVCNPSKFLEALRGEEHQQLISNLNAKFDKMQKGWVQMDKEGQPAPKHKNKADRLKEIWKSKRRVRKSRPLEQQKFSPVQMLFMKPFDLTSICRWFLQSTETKSLVIVKKVNTRLPSETQLCFHSSSAGAGSANGIFPSLQAERLKKHLKKFAIASPVKSNPKNQRLISKALGQGISLMSKEKPKPTTATRICTKAQSLAGVTPVQVPESISATAGSAKNPASARILRKYSNMREKLQVQQNKKCKEKALKSAGLKATIIPKKDDKEKLQTQKGPKSVVVKKISSLSKTAKANSVLKERALKSEDGSSTKRLQGLKRITQAIGAHASANKLSKKLVRTDKAQRVKSIKVDSKKSALQKIPPEPQTLDVDSKSSEDQVLTRSQRKMEGAPSQTASPKSTMKRGLEPLVTPTKRTRTSKP", "length": 1668, "header": "tr|A0A8N7UUM9-1|A0A8N7UUM9_DANRE Isoform 1 of Uncharacterized protein wu:fc17b08 isoform X1 OS=Danio rerio OX=7955 GN= PE=1 SV=1 CANONICAL=A0A8N7UUM9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:556205", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556205", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5Y016-1", "protein_name": "Ligand dependent nuclear receptor corepressor", "gene_name": "Lcor", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRMIQQFAAEYTSKNSSTQDPSQPNSTKNQSLPKASPVTTSPTAATPQNPVLSKLLMADQDSPLDLTVRKSQSEPSEQDGVLDLSTKKSPCASSTSLSHSPGCSSTQGNGEDSAEAPVADSNHPSKSPLEKFMVKLCTHHQKQFIRVLSDLYTESQPGSEDLQPLGPSVMDVSARDSDCAGLGSRDDEKDDACLDGGSPASVKLFLDSSGSPSSLNVTEETMKDPPPETDSVDGRENALSTVQKDSSGPPDAQQNPTGSADSPTVGCLSTLDSSSFNSPHSSKSLEGQTTGQEQDTDMKPREDAEDSAPASVQSLAAVELVAENTEEGGSCIVSQRNSFKALSEETWDSGFMGNSSSAADKENALQCGSRTSSPQDLETDEQDARPKQENHLHSVGRNKAGFQPYPRDKGHFDHSKGGWLAPSPTPAVHRASNGHSQTKMISASIKTARKSKRASGLRINDYDNQCDVVYISQPITECHFENQRSILSSRKTARKSTRGYFFNGDCCELPTVRTLARNLCSQEKGSCSPLTSEAVVTPKQTLTGPTSKHTVGVQLPTVGVQLPPGGVQLPTGGAQLPTVDAQLPTGGVQLPTADVQLPTVGIQLATADEQLPTVGAQLPTADEQLPTVGAQLATADEQLPTVGAQLPTADEQLPTVGAQLPTADEQLPTVGAQLPTADEQLPTVGAQLATADEQLPTVGAQLPAADEQLPSVGAQLPTADEQLPSVGAQLPTADVQLPSVNAQLPTADVQLPSVNAQLPTVDVQLPSVNAQFPTVDVQLPSVNAQFPTADVQLPSVNAQLPTVDVQLPSVNAQLPTVDVQLPSVDVQIPTVDMQLPIAGEQLLKEDTRDDPRKERTSLEEGDKDTSSAKEHQEPEVCLTKNERDPSVSPRPGETTPSSPACLLPAALTNEDPSEMPEGSTVVSSPTASVLSFHEQDQPPAASLLGPEEMQAQECHLVLTGGSIPLTSGEGSEDLPWRPQFSPETAVREGRSPCSADKSPAMALDPPLSLELSEHDQSSSTEAEARDTPGETLLLDGSLPLLESSIVTDEKNPSQTEGGEVASGTGHLEAHDEDIKYSAENDPSEPNSGSPEENVDKKKKAKKLPEASDRCLRSQLVDSSSADRYPGSQGLDSNAACSEVNVSKNHAVKHSKREGDCGGVTSEGSVIDSNHTDSLEDTENPGVSEHSSDEETKQEAEGLGVITRQTVKNLLAKEVKREEGGTSPSSDPATVSQPSPQDNLGTRVWSKIDEKDAHVPSDSIPCKRDPEQVKENPGHIVIQDTEAAVREVDAEDTHHEDGAGRAPCSSAAISASQSGDAAGPPKLVRRPKRLPSSTYNLRPAHCVGALDTAKMTSEKQVTQVNPAPKESGASPSAESLDEEDSDTVAEEQPKFVGWCAEEENQELIASFNAQYLRVQKGWIQLEKETQPTSRARSKSDKLKEIWKSKKRSRKCRGSLEVQKFSPVQMLFMTNFKLSNICKWFLETTETRSLVIVKKLNTRLPGDIPLVKHPLQKYPPSTMYPSSLQAERLKKHLKKFPGAIPARNNWKTQKLWAKLRENPEQVEPDAGSDISLGPNSEDSVEEVRESRHSHPPTNLPTPASTRILRKYSNIRGKLRAQRLDSSVGGASEIKQGRKSVCINPLMSPKLALQVGADGFPVNPKRAERSKGRRGKQMPETLLKVEGQNKRKRAEGSGTQDGKDKGPATKASRVLSAAKKLAAKDRVNQLSKKMTLKENKVRVCRKGPGKSCPASRKEKENANRRPGHPTAASAALAKPSKQRGAREASSKPPKARRRNRKLSSGRGRARPLAKSPENRTAPRKRKLKAKLDSSQGKRRRLEAK", "length": 1838 }, "evidence": [ { "id": "RGD:1311704", "url": "https://alliancegenome.org/gene/RGD:1311704#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2746", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2746#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96JN0-1", "protein_name": "Ligand-dependent corepressor", "gene_name": "LCOR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQRMIQQFAAEYTSKNSSTQDPSQPNSTKNQSLPKASPVTTSPTAATTQNPVLSKLLMADQDSPLDLTVRKSQSEPSEQDGVLDLSTKKSPCAGSTSLSHSPGCSSTQGNGRPGRPSQYRPDGLRSGDGVPPRSLQDGTREGFGHSTSLKVPLARSLQISEELLSRNQLSTAASLGPSGLQNHGQHLILSREASWAKPHYEFNLSRMKFRGNGALSNISDLPFLAENSAFPKMALQAKQDGKKDVSHSSPVDLKIPQVRGMDLSWESRTGDQYSYSSLVMGSQTESALSKKLRAILPKQSRKSMLDAGPDSWGSDAEQSTSGQPYPTSDQEGDPGSKQPRKKRGRYRQYNSEILEEAISVVMSGKMSVSKAQSIYGIPHSTLEYKVKERLGTLKNPPKKKMKLMRSEGPDVSVKIELDPQGEAAQSANESKNE", "length": 433 }, "evidence": [ { "id": "RGD:1311704", "url": "https://alliancegenome.org/gene/RGD:1311704#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1015, "end_pos": 1017, "annotation": "n_glycosylation_sequon" }, { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1081, "end_pos": 1083, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1178, "end_pos": 1180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 505, "end_pos": 507, "annotation": "n_glycosylation_sequon" }, { "start_pos": 998, "end_pos": 1000, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1015, "end_pos": 1017 }, { "start_pos": 106, "end_pos": 108 }, { "start_pos": 1081, "end_pos": 1083 }, { "start_pos": 1178, "end_pos": 1180 }, { "start_pos": 231, "end_pos": 233 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 505, "end_pos": 507 }, { "start_pos": 998, "end_pos": 1000 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UUX0-1", "uniprot_ac": "A0A8N7UUX0", "uniprot_id": "A0A8N7UUX0_DANRE", "mass": { "chemical_mass": 59308.0, "monoisotopic_mass": 59308.0 }, "refseq": { "ac": "XP_683329", "name": "uncharacterized protein si:ch73-70k4.1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683329" }, "gene_names": [ { "name": "si:ch73-70k4.1", "type": "recommended", "evidence": [ { "id": "A0A8N7UUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX0" } ] }, { "name": "si:ch73-70k4.1", "type": "synonym", "evidence": [ { "id": "XP_683329", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683329" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch73-70k4.1", "type": "synonym", "evidence": [ { "id": "A0A8N7UUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch73-70k4.1", "type": "synonym", "evidence": [ { "id": "XP_683329", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683329" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_683329.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_683329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683329" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch73-70k4.1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-3788", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3788", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUX0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UUX0", "database": "AlphaFoldDB", "categories": [] }, { "id": "555663", "url": "https://www.ncbi.nlm.nih.gov/gene/555663", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:555663", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555663", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR37862", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37862", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37862:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37862:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15750", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15750", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_683329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683329", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UUX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-3788", "url": "https://zfin.org/ZDB-GENE-030131-3788", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MQCVYNRMTVMSKLKRKKLSVEDYKSEQQTLIKKLNDSRCSVALQDSSCATTSTGRERWWESSELSDAERLWALTLTALCPNLQSDDLEESIPQLPPPSSTKSPVQTVSDWRWCNGNKDVNPPPGLPAPSFLVHPPPANDPKNPSQPPAEENTRASDPPSLSDQEKHASSPDGDSVPVCSTQTTQQRKLDDGVNCLEDCKLLDDQGDRFGQARNVSETRRSQAESRTVRSVEGKSAEMGAGKSESGIRTFSGAEGPALVLETKQEASGSGSGQEAKTGAGQRAKSGVREFGLGTGTKSGIAKGAKSGLGRNSIASGSGLDLGTKSGASRSGLVLGTKSGASGSGLVLGTKSGASGSGLVLGTKSGASGSGLVLGAKSGSGQEAKSGLVRSGSGLVQSGTVQEEENGLMVFRSGLGTNARASGSKLGMETKSGTEWEAKSGIRGSGTNSVEEKIANSGSSESGLGLETKSGTEQEAKSGTRESGTNSGEEKLAKSGLGRSGANSGASRSGSGLETTRSPEGSESGLETKSGAEHRSELECCPMCLMPFPAGFTQMECDGHLAQCLSEMHDDIIW", "length": 573, "header": "tr|A0A8N7UUX0-1|A0A8N7UUX0_DANRE Isoform 1 of Uncharacterized protein si:ch73-70k4.1 OS=Danio rerio OX=7955 GN=si:ch73-70k4.1 PE=4 SV=2 CANONICAL=A0A8N7UUX0-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UUX0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX0/entry#A0A8N7UUX0-1", "sequence": { "sequence": "MQCVYNRMTVMSKLKRKKLSVEDYKSEQQTLIKKLNDSRCSVALQDSSCATTSTGRERWWESSELSDAERLWALTLTALCPNLQSDDLEESIPQLPPPSSTKSPVQTVSDWRWCNGNKDVNPPPGLPAPSFLVHPPPANDPKNPSQPPAEENTRASDPPSLSDQEKHASSPDGDSVPVCSTQTTQQRKLDDGVNCLEDCKLLDDQGDRFGQARNVSETRRSQAESRTVRSVEGKSAEMGAGKSESGIRTFSGAEGPALVLETKQEASGSGSGQEAKTGAGQRAKSGVREFGLGTGTKSGIAKGAKSGLGRNSIASGSGLDLGTKSGASRSGLVLGTKSGASGSGLVLGTKSGASGSGLVLGTKSGASGSGLVLGAKSGSGQEAKSGLVRSGSGLVQSGTVQEEENGLMVFRSGLGTNARASGSKLGMETKSGTEWEAKSGIRGSGTNSVEEKIANSGSSESGLGLETKSGTEQEAKSGTRESGTNSGEEKLAKSGLGRSGANSGASRSGSGLETTRSPEGSESGLETKSGAEHRSELECCPMCLMPFPAGFTQMECDGHLAQCLSEMHDDIIW", "length": 573, "header": "tr|A0A8N7UUX0-1|A0A8N7UUX0_DANRE Isoform 1 of Uncharacterized protein si:ch73-70k4.1 OS=Danio rerio OX=7955 GN=si:ch73-70k4.1 PE=4 SV=2 CANONICAL=A0A8N7UUX0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:555663", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555663", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AAA5-1", "protein_name": "Fanconi anemia core complex-associated protein 20", "gene_name": "Faap20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEERRLRGRLSRRRPPAGGGPPNCRPWFLSEESKSEPWAALLRSTVGGNTDWTPNSQPLPPLPAFPSQESLPDPESTVPPEVFTVGSKTFSWTPFPPALRGSGSSCRLLRCPEGSPGSPAPSLKGCPALDSRQTPSTQECVQSQLVLLNCPLCQKAFDPKLTQLDVDSHLAQCLAESTEDVVW", "length": 184 }, "evidence": [ { "id": "RGD:1308923", "url": "https://alliancegenome.org/gene/RGD:1308923#orthology", "database": "AGR" }, { "id": "MGI:1914763", "url": "https://alliancegenome.org/gene/MGI:1914763#orthology", "database": "AGR" }, { "id": "HGNC:26428", "url": "https://alliancegenome.org/gene/HGNC:26428#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3788", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3788#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UN58-1", "protein_name": "Fanconi anemia core complex-associated protein 20", "gene_name": "Faap20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEERRLRGRLSRRRPPAGGGPPNCRPWFLSEGSKSEPWAALLRSTVSGTADWTPNRQPLPPLPAFPSQESLPDPESTVPPEAFTVGSKTFSWTPLPPALRGSGSSRHLFCEPEGSLGSPTPSLKGCPALNSGRTPSAQECVPVQSPLALLSCPLCQKAFDPKLTQLDVDSHLAQCLAECTEDVVW", "length": 186 }, "evidence": [ { "id": "RGD:1308923", "url": "https://alliancegenome.org/gene/RGD:1308923#orthology", "database": "AGR" }, { "id": "MGI:1914763", "url": "https://alliancegenome.org/gene/MGI:1914763#orthology", "database": "AGR" }, { "id": "HGNC:26428", "url": "https://alliancegenome.org/gene/HGNC:26428#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3788", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3788#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6NZ36-1", "protein_name": "Fanconi anemia core complex-associated protein 20", "gene_name": "FAAP20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAARRPRLGLSRRRPRPAGGPSGGRPWFLLGGDERERLWAELLRTVSPELILDHEVPSLPAFPGQEPRCGPEPTEVFTVGPKTFSWTPFPPDLWGPGRSYRLLHGAGGHLESPARSLPQRPAPDPCRAPRVEQQPSVEGAAALRSCPMCQKEFAPRLTQLDVDSHLAQCLAESTEDVTW", "length": 180 }, "evidence": [ { "id": "RGD:1308923", "url": "https://alliancegenome.org/gene/RGD:1308923#orthology", "database": "AGR" }, { "id": "MGI:1914763", "url": "https://alliancegenome.org/gene/MGI:1914763#orthology", "database": "AGR" }, { "id": "HGNC:26428", "url": "https://alliancegenome.org/gene/HGNC:26428#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-3788", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-3788#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUX0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UUX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUX0" }, { "id": "PS51906", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51906" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UBZ2-type", "eco_id": "ECO_0000259", "start_pos": 537, "end_pos": 573, "start_aa": "Leu", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 214, "end_pos": 216 }, { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVA7-1", "uniprot_ac": "A0A8N7UVA7", "uniprot_id": "A0A8N7UVA7_DANRE", "mass": { "chemical_mass": 136271.0, "monoisotopic_mass": 136271.0 }, "refseq": { "ac": "XP_697773", "name": "PGC-1 and ERR-induced regulator in muscle protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697773" }, "gene_names": [ { "name": "perm1a", "type": "recommended", "evidence": [ { "id": "A0A8N7UVA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA7" } ] }, { "name": "perm1a", "type": "synonym", "evidence": [ { "id": "XP_697773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697773" } ] } ], "protein_names": [ { "name": "PGC-1 and ERR-induced regulator in muscle protein 1", "type": "synonym", "evidence": [ { "id": "XP_697773", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697773" }, { "id": "A0A8N7UVA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_697773.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_697773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697773" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "perm1a", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-358", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-358", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVA7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UVA7", "database": "AlphaFoldDB", "categories": [] }, { "id": "569303", "url": "https://www.ncbi.nlm.nih.gov/gene/569303", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR043442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569303", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569303", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR47282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47282:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47282:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28384", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28384", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_697773", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697773", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVA7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-358", "url": "https://zfin.org/ZDB-GENE-090313-358", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDDFEYSVQISDQDWDCFFQECEGCDLLSPVLASREDSGMSDIDEMSCRFIGRTPAMDTASVNPDPECQIDGPSDSEGSPVCNYLSKYGIRSPEQVLSGSEEDLHLQTVNLFFEQLKSVEENEQPVKQSRVDNWGSETTGHLECLIDKQDIRTADTGPSGPNRTRLTGETAKQGVANTWGSKAFKKPAYANAQEDASKSDSELVIAKKSLSTPLITVRMKQEQQRRFCDPCKDLDLKPESKSPDKEKMVLVNKKVIASPNPARLAYLDAISSSDSKDSPISQIQLSPSNLRRKRRKKKRMTVEPAEPGYESQIHIRANESEDEKFVQREEMNCLPANVWKTNHLSLQGIKMPLTAQNTDHLQFRNLFDLEASADFKFSKSLPVSFTRDLGISPPKPEAEHACFNTISKSMRDMSLANNEQLKSEICEFSLLPKIDKVLNLQESALNVTKLLQLDPAVQLPKDMTGIKETLLAPLCDNSDAGCQRNSLLSPNISSAVDSTEAPPSVVSFKLTEDKDKTDCSAVKDEQTIPSKRNTVEISGSKESILSLPDNQNGVESCSYENDPETFTCLQNAPQKVEAGIQVNISDSQSHVASQTIEINTNTPVSETYAKVESHVPDKMDHRTDYDHMQNKISKVTVNASPIKPGNLDDSDNISANVVAVSAEGEQLLCSKSTEFSEHISHATEEIQSAEKLQDTLAEMNSTSSTELKSGDNDTESVSLDPPSPVFAISSFWNEMEKLTINDILKLRLVGNSQHTSILTQPEESSIVDITDAADSGYFTQLDDSKQDRLSGDLSYISDLDEELGQLQTPFSSKQEDELCESPSSSGVMWENDPDSVGVGEKIVHTSSETTLPEHLYTANPQQCFRRMCKNLSVQNLQALDSPPIRQILRNASMHSIHSEVEDDFIDPFYHVNTSSSKVLSDDEEEVENRGITFSEVIQFFFGEDEPERCASHADNVAASYLDGTGTSLPETYDHFFSEFDSGTFVCPIVEESCSDQMVPIFSCSRSTNKNIQFPEAYDYFFPDSPGNSDDENENAVIKVVTRYDHKPPSHDHVDMYEHFYSEEESDFLRTNPLSFRKIRRTGCTDPEEKTCSGELVPVKRFPKGIIQPLNASGPDGSPFPDSLLLNLENRIFQQLNEQQKKCMEMQTIVADPRLDAPFLPLKQADMCLVCIAFASWVLKSTGSGGDTWKAALLANVSALSAIRYLRRHKREEVSGKTPLRQIEPA", "length": 1225, "header": "tr|A0A8N7UVA7-1|A0A8N7UVA7_DANRE Isoform 1 of PGC-1 and ERR-induced regulator in muscle protein 1 OS=Danio rerio OX=7955 GN=perm1a PE=4 SV=2 CANONICAL=A0A8N7UVA7-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA7/entry#A0A8N7UVA7-1", "sequence": { "sequence": "MDDFEYSVQISDQDWDCFFQECEGCDLLSPVLASREDSGMSDIDEMSCRFIGRTPAMDTASVNPDPECQIDGPSDSEGSPVCNYLSKYGIRSPEQVLSGSEEDLHLQTVNLFFEQLKSVEENEQPVKQSRVDNWGSETTGHLECLIDKQDIRTADTGPSGPNRTRLTGETAKQGVANTWGSKAFKKPAYANAQEDASKSDSELVIAKKSLSTPLITVRMKQEQQRRFCDPCKDLDLKPESKSPDKEKMVLVNKKVIASPNPARLAYLDAISSSDSKDSPISQIQLSPSNLRRKRRKKKRMTVEPAEPGYESQIHIRANESEDEKFVQREEMNCLPANVWKTNHLSLQGIKMPLTAQNTDHLQFRNLFDLEASADFKFSKSLPVSFTRDLGISPPKPEAEHACFNTISKSMRDMSLANNEQLKSEICEFSLLPKIDKVLNLQESALNVTKLLQLDPAVQLPKDMTGIKETLLAPLCDNSDAGCQRNSLLSPNISSAVDSTEAPPSVVSFKLTEDKDKTDCSAVKDEQTIPSKRNTVEISGSKESILSLPDNQNGVESCSYENDPETFTCLQNAPQKVEAGIQVNISDSQSHVASQTIEINTNTPVSETYAKVESHVPDKMDHRTDYDHMQNKISKVTVNASPIKPGNLDDSDNISANVVAVSAEGEQLLCSKSTEFSEHISHATEEIQSAEKLQDTLAEMNSTSSTELKSGDNDTESVSLDPPSPVFAISSFWNEMEKLTINDILKLRLVGNSQHTSILTQPEESSIVDITDAADSGYFTQLDDSKQDRLSGDLSYISDLDEELGQLQTPFSSKQEDELCESPSSSGVMWENDPDSVGVGEKIVHTSSETTLPEHLYTANPQQCFRRMCKNLSVQNLQALDSPPIRQILRNASMHSIHSEVEDDFIDPFYHVNTSSSKVLSDDEEEVENRGITFSEVIQFFFGEDEPERCASHADNVAASYLDGTGTSLPETYDHFFSEFDSGTFVCPIVEESCSDQMVPIFSCSRSTNKNIQFPEAYDYFFPDSPGNSDDENENAVIKVVTRYDHKPPSHDHVDMYEHFYSEEESDFLRTNPLSFRKIRRTGCTDPEEKTCSGELVPVKRFPKGIIQPLNASGPDGSPFPDSLLLNLENRIFQQLNEQQKKCMEMQTIVADPRLDAPFLPLKQADMCLVCIAFASWVLKSTGSGGDTWKAALLANVSALSAIRYLRRHKREEVSGKTPLRQIEPA", "length": 1225, "header": "tr|A0A8N7UVA7-1|A0A8N7UVA7_DANRE Isoform 1 of PGC-1 and ERR-induced regulator in muscle protein 1 OS=Danio rerio OX=7955 GN=perm1a PE=4 SV=2 CANONICAL=A0A8N7UVA7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:569303", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569303", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZH76-1", "protein_name": "PPARGC1 and ESRR induced regulator, muscle 1", "gene_name": "Perm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDNFQYSVQLSDREWAEFSATADECGLLQADLASGDEPLSSDIDQGDSSGSSPPGPPPLFTGQLVSQGRGQQGCELEDVAAQQLVSRSQCEPVLALEASHQVVSTSTQSEALPFPSSDSVCPGQALSFPGSATFTDKMQRLLQGPAPSSPGKPPHSPESPGHSAIPQSPPDSLEASPQKPGRKKRRGVGAKGTKYSGSPDSAAIQMSSPQLTEARPKKVLMSGTLIAKSQQDKPQSDSTGAPEHDSSIPEQMARQESGSDLPTPTPITEQDTDQIGKKSRAVLHLVSKPVQEVHPDISMATPNMSKPATKPQPYMALSKPASKPQPDIASSTHPFTPDMALSTLAFKCQPHTNQSTPASEPDMALSTTASMSQLGKADFASSCTPGLHVDLSAAGSEIKTEVSPSVPASVDVLSTDLPHSVSKTESTESVSIPVMPSLSPISQAEAAVVDTAVTLPPGGNIEKPVGQFSAGSSGEPCLGPVQGPKKKKVRFSMAIPSHEESRSGEPTGSSSLTPDWPSAPRTAAGSRGGSAAWDAVAVGPRLPQPRILKHLPPPISSVSAEAEPGSCFAVTLPEAYEFFFCDTIEEEDEDVEDEEAASQALDEVQWPDTCEFFFRDSRAQRSRCQRGHSSVSPPRADTVAPVPPGDLVPISIPEVYEHFFPEEGFGNRQPPATHIQMQTSELSREVGPEAPSNPVPPTAEHLSLTIRKAGELRSPLTSFKFSQNDMCLVFVAFATWAVRTSDLHAPDAWKTVLLANIGTISAIRYFRRQVGRGHGGRPRPSSSSDPSC", "length": 788 }, "evidence": [ { "id": "HGNC:28208", "url": "https://alliancegenome.org/gene/HGNC:28208#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q149B8-1", "protein_name": "PGC-1 and ERR-induced regulator in muscle protein 1", "gene_name": "Perm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDNFQYSVQLSDREWAEFSATADECGLLQADLASGDEPLSSDIDQGDSSGSSPPGPPPLFTGQLVSQGRGQQSRELEDVAAQQLVSRSQCEPVLALEASHQVAGTSTQSEAPLFPSLDSVCPGQALSFPGPATCRDKMQRLLQGPAPSSPSKAPHSPESPGHSDNPQSSPDSLEASPRNPGRKKRRAVGAKGTKHSGSLDSAATQMSSPQLTRPKEALMSGTLMAKAQQDKPQPDSTSPEQMAREESGLDLSTPILITEQDQIRKTSRAALHVVSKPVQEVHPDVPMASPNVSTRASKPQPDVALPKPASKPQSDIASSTHPFTPDVSLSTLAFKCQPNTNQSTPASEPDMALSTPASEPDTALSTPASEPDTALSTPASEPDTALSTPASRSQLVKAEFASACTPGLHVDLSAAGSEIKPEVSSSMPAAVDVLRTDLPRSVSKTESKESVSIPVKPSLSPISQAEAAMVDTGVSVPPGGSIEKPAGQFSAGSSGESCLGPVQAPKKKKVRFSMAIPSHEDSGSGEPTGSPFLTPEQPPVPRTAAGSRGGSAAWDAVAVAPRLPQPRILKHLPPPVSSVSAEAESGNCFAVTLPEAYEFFFCDTIEEEDEDVEDEEAASQALDEVQWPDTCEFFFRDSRAQRSRCQRGHSPVSPPRADTVAPVPPEGLVPISIPEVYEHFFTEEGFGHRQPAATPMQTSELSREGGLEASTKPVSPTAEHLSLTVRKAGELRSPLTSFTFSQNDMCLVFVAFATWAVRTSDLQAPDAWKTVLLANIGTISAIRYFRRQVGRGHSGRPRSSSSSNPSC", "length": 807 }, "evidence": [ { "id": "HGNC:28208", "url": "https://alliancegenome.org/gene/HGNC:28208#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5SV97-1", "protein_name": "PGC-1 and ERR-induced regulator in muscle protein 1", "gene_name": "PERM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENFQYSVQLSDQDWAEFSATADECGLLQAGLASGDELLSSDIDQGDSSGSSPPRAPPLPTGQLAAGGRSRRGCEEEDVATQQPVSRSQGEPVLALGTGQQTPSTSARAEAPPSLGPGASPPSQFSSCPGPASSGDQMQRLLQGPAPRPPGEPPGSPKSPGHSTGSQRPPDSPGAPPRSPSRKKRRAVGAKGGGHTGASASAQTGSPLLPAASPETAKLMAKAGQEELGPGPAGAPEPGPRSPVQEDRPGPGLGLSTPVPVTEQGTDQIRTPRRAKLHTVSTTVWEALPDVSRAKSDMAVSTPASEPQPDRDMAVSTPASEPQSDRDMAVSTPASEPQPDTDMAVSTPASEPQPDRDMAVSIPASKPQSDTAVSTPASEPQSSVALSTPISKPQLDTDVAVSTPASKHGLDVALPTAGPVAKLEVASSPPVSEAVPRMTESSGLVSTPVPRADAAGLAWPPTRRAGPDVVEMEAVVSEPSAGAPGCCSGAPALGLTQVPRKKKVRFSVAGPSPNKPGSGQASARPSAPQTATGAHGGPGAWEAVAVGPRPHQPRILKHLPRPPPSAVTRVGPGSSFAVTLPEAYEFFFCDTIEENEEAEAAAAGQDPAGVQWPDMCEFFFPDVGAQRSRRRGSPEPLPRADPVPAPIPGDPVPISIPEVYEHFFFGEDRLEGVLGPAVPLPLQALEPPRSASEGAGPGTPLKPAVVERLHLALRRAGELRGPVPSFAFSQNDMCLVFVAFATWAVRTSDPHTPDAWKTALLANVGTISAIRYFRRQVGQGRRSHSPSPSS", "length": 790 }, "evidence": [ { "id": "HGNC:28208", "url": "https://alliancegenome.org/gene/HGNC:28208#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-358", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-358#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1110, "end_pos": 1112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1195, "end_pos": 1197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" }, { "start_pos": 638, "end_pos": 640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" }, { "start_pos": 870, "end_pos": 872, "annotation": "n_glycosylation_sequon" }, { "start_pos": 890, "end_pos": 892, "annotation": "n_glycosylation_sequon" }, { "start_pos": 912, "end_pos": 914, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1110, "end_pos": 1112 }, { "start_pos": 1195, "end_pos": 1197 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 491, "end_pos": 493 }, { "start_pos": 583, "end_pos": 585 }, { "start_pos": 638, "end_pos": 640 }, { "start_pos": 652, "end_pos": 654 }, { "start_pos": 700, "end_pos": 702 }, { "start_pos": 712, "end_pos": 714 }, { "start_pos": 870, "end_pos": 872 }, { "start_pos": 890, "end_pos": 892 }, { "start_pos": 912, "end_pos": 914 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UYV2-1", "uniprot_ac": "A0A8N7UYV2", "uniprot_id": "A0A8N7UYV2_DANRE", "mass": { "chemical_mass": 10739.0, "monoisotopic_mass": 10739.0 }, "refseq": { "ac": "NP_001116743", "name": "small integral membrane protein 24 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116743" }, "gene_names": [ { "name": "smim24", "type": "recommended", "evidence": [ { "id": "A0A8N7UYV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UYV2" } ] }, { "name": "si:ch211-133l5.7", "type": "synonym", "evidence": [ { "id": "NP_001116743", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116743" }, { "id": "A0A8N7UYV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UYV2" } ] }, { "name": "smim24", "type": "synonym", "evidence": [ { "id": "NP_001116743", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116743" } ] } ], "protein_names": [ { "name": "Small integral membrane protein 24 precursor", "type": "synonym", "evidence": [ { "id": "A0A8N7UYV2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UYV2/entry#names_and_taxonomy" } ] }, { "name": "small integral membrane protein 24 precursor", "type": "synonym", "evidence": [ { "id": "NP_001116743", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116743" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH492283.1, GDQH01000916.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476762 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Apr 11, 2008 this sequence version replaced XP_692569.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001116743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116743" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UYV2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UYV2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "smim24", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UYV2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-117", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "564121", "url": "https://www.ncbi.nlm.nih.gov/gene/564121", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR031627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564121", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564121", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HGFYENI", "url": "https://omabrowser.org/oma/group/HGFYENI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR15296", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15296", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15296:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15296:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15807", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15807", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001116743", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116743", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UYV2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UYV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UYV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UYV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-117", "url": "https://zfin.org/ZDB-GENE-081104-117", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFHLKNIAAFIILSACIYQAQAGGQRATSDTGKVTLQPWLVGLAAVVGFLFIVFVALIIQRLFFKKDKSAEKAEKHGFYENIAADLEASEETKQTNF", "length": 97, "header": "tr|A0A8N7UYV2-1|A0A8N7UYV2_DANRE Isoform 1 of Small integral membrane protein 24 precursor OS=Danio rerio OX=7955 GN=smim24 PE=3 SV=1 CANONICAL=A0A8N7UYV2-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UYV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UYV2/entry#A0A8N7UYV2-1", "sequence": { "sequence": "MFHLKNIAAFIILSACIYQAQAGGQRATSDTGKVTLQPWLVGLAAVVGFLFIVFVALIIQRLFFKKDKSAEKAEKHGFYENIAADLEASEETKQTNF", "length": 97, "header": "tr|A0A8N7UYV2-1|A0A8N7UYV2_DANRE Isoform 1 of Small integral membrane protein 24 precursor OS=Danio rerio OX=7955 GN=smim24 PE=3 SV=1 CANONICAL=A0A8N7UYV2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UYV2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UYV2" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UYV2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UYV2" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "A temporal single cell transcriptome atlas of zebrafish anterior segment development.", "journal": "Sci. Rep.", "date": "2023", "authors": "V\u00f6cking Oliver, Famulski J K", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UYV2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UYV2" } ], "reference": [ { "type": "PubMed", "id": "37024546", "url": "https://glygen.org/publication/PubMed/37024546" } ] } ], "pathway": [ { "id": "dre:564121", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564121", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1Y7VJ29-1", "protein_name": "Predicted gene, 48552", "gene_name": "Gm48552", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSVDEKEAEDWSPAPPMYEEYRPPALDAIRLPRYALYLLMAAILVVAVAYAIVGHLIKDLAHDLADWAFGPKPDQEEEGSRELRASLAAEDLEELDLQLALAWRGEDDPARAPRRTSIAFKDPPVQTNFWRLD", "length": 135 }, "evidence": [ { "id": "RGD:7506385", "url": "https://alliancegenome.org/gene/RGD:7506385#orthology", "database": "AGR" }, { "id": "MGI:6098105", "url": "https://alliancegenome.org/gene/MGI:6098105#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-117#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A286YF18-1", "protein_name": "Small integral membrane protein 44", "gene_name": "SMIM44", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGLAAEGEAEGWSPSPPLYEEYRPPPLDSIRLPRYVLYLLLAALVVVAVAYAIVGHLIKDLAHDLADWAFGPKPDQEAAPRELRPSLTGEDLEGLDLQLALAWQGEEDAGGGGEGAPSEPPPPPEPRRPSIAFKDPPSRSSFWKLMAT", "length": 149 }, "evidence": [ { "id": "RGD:7506385", "url": "https://alliancegenome.org/gene/RGD:7506385#orthology", "database": "AGR" }, { "id": "MGI:6098105", "url": "https://alliancegenome.org/gene/MGI:6098105#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A8I6A1C1-1", "protein_name": "Small integral membrane protein 44", "gene_name": "Smim44", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGSLDEREAEDWSPAPPMYEEYRPPALDTIRLPRYALYLLMAAILVVAVAYAIVGHLIKDLAHDLADWAFGPKPDQEEGPRELRASLAAEDLEELDLQLALAWRGEEDPAYAPRRTSIAFKDPPVQTNFWRLD", "length": 134 }, "evidence": [ { "id": "RGD:7506385", "url": "https://alliancegenome.org/gene/RGD:7506385#orthology", "database": "AGR" }, { "id": "MGI:6098105", "url": "https://alliancegenome.org/gene/MGI:6098105#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-117#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LDZ9-1", "protein_name": "Small integral membrane protein 24", "gene_name": "Smim24", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTLGRLLLLATLFLTPAEAQQASERRLKPWLVGLAAVVGFLFIVFILMLVNRVWCSKDRAEDEEATFRMDHIVNQNSKPSKADKKKQKVGRKGGQSNEGLDLEEEFSDDERDKKTAL", "length": 118 }, "evidence": [ { "id": "HGNC:37244", "url": "https://alliancegenome.org/gene/HGNC:37244#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75264-1", "protein_name": "Small integral membrane protein 24", "gene_name": "SMIM24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METLGALLVLEFLLLSPVEAQQATEHRLKPWLVGLAAVVGFLFIVYLVLLANRLWCSKARAEDEEETTFRMESNLYQDQSEDKREKKEAKEKEEKRKKEKKTAKEGESNLGLDLEEKEPGDHERAKSTVM", "length": 130 }, "evidence": [ { "id": "HGNC:37244", "url": "https://alliancegenome.org/gene/HGNC:37244#orthology", "database": "AGR" }, { "id": "MGI:1919523", "url": "https://alliancegenome.org/gene/MGI:1919523#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-117#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q0VG18-1", "protein_name": "Small integral membrane protein 24", "gene_name": "Smim24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDTLGRLLLLATLFLTPAEAQQASERRLKPWLVGLAAVVGFLFIVFILMLANRVWCAKGRAEDEEATFRMEHIMNENSQPSKADKKQKKKVDRKGGQSNEALELEEKESSDEERGKKTAL", "length": 120 }, "evidence": [ { "id": "HGNC:37244", "url": "https://alliancegenome.org/gene/HGNC:37244#orthology", "database": "AGR" }, { "id": "MGI:1919523", "url": "https://alliancegenome.org/gene/MGI:1919523#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-117#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q90X36-1", "protein_name": "PDZK1-interacting protein 1 precursor", "gene_name": "pdzk1ip1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKPVSVFYWFLLTLGLVAAQAETAGRALPNWLTGIIAVAVFLFLVFISFLVNKAWCNNPSQPEAVIPNAYAMTNGSSIHETSLDAVRSGDGPNMYENVIVHQTEEKVTAM", "length": 111 }, "evidence": [ { "id": "HGNC:37244", "url": "https://alliancegenome.org/gene/HGNC:37244#orthology", "database": "AGR" }, { "id": "MGI:1919523", "url": "https://alliancegenome.org/gene/MGI:1919523#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UYV2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UYV2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5WUJ5-1", "uniprot_ac": "A5WUJ5", "uniprot_id": "A5WUJ5_DANRE", "mass": { "chemical_mass": 42160.0, "monoisotopic_mass": 42160.0 }, "refseq": { "ac": "NP_001093553", "name": "uncharacterized protein LOC100003110 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093553" }, "gene_names": [ { "name": "si:dkey-83f18.11", "type": "recommended", "evidence": [ { "id": "A5WUJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUJ5" } ] }, { "name": "si:dkey-83f18.11", "type": "synonym", "evidence": [ { "id": "NP_001093553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093553" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100003110 precursor", "type": "synonym", "evidence": [ { "id": "A5WUJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUJ5/entry#names_and_taxonomy" } ] }, { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A5WUJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUJ5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100003110 precursor", "type": "synonym", "evidence": [ { "id": "NP_001093553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093553" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588729.7091982.1, SRR32588718.26662517.1 [ECO:0000332] RNAseq introns :: partial sample support SAMN18715719 [ECO:0000350] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000007.1. On Jul 26, 2007 this sequence version replaced XP_001342742.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001093553", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093553" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUJ5", "url": "https://www.uniprot.org/uniprotkb/A5WUJ5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-83f18.11", "url": "https://www.uniprot.org/uniprotkb/A5WUJ5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-496", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-496", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03602", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03602", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100003110", "url": "https://www.ncbi.nlm.nih.gov/gene/100003110", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100003110", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003110", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VECEFIC", "url": "https://omabrowser.org/oma/group/VECEFIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5WUJ5", "url": "https://www.orthodb.org/?gene=A5WUJ5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001093553", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093553", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5WUJ5", "url": "https://www.uniprot.org/uniprotkb/A5WUJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WUJ5-1", "url": "https://www.uniprot.org/uniprotkb/A5WUJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-496", "url": "https://zfin.org/ZDB-GENE-070705-496", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGQFLDSLLLLVALCSISECVQRQYHFINEMKTWTEAQRYCREKYTDLATVDNMNDMIQLMKSVKVNDRGVWIGLQRKWQWSSGDPALFLHWGNEQPDGADECAFMRNGQWEDGKCNDSWIFVCYNMSRGLVFVNQAMTWRAAQSYCRQNHTDLVSVRNQNESQQLEKFINDSHKFASEVWIGLFRDSWQWSDRSNYSFSYWNNQEPNDYGGKENCTVVQPKTEGRWNDIVCNNLFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYKVMNVVKLASTEAVWLGLRHSCALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRSGAVQSGGSQTWISRPETHKLNFICRNY", "length": 362, "header": "tr|A5WUJ5-1|A5WUJ5_DANRE Isoform 1 of Uncharacterized protein LOC100003110 precursor OS=Danio rerio OX=7955 GN=si:dkey-83f18.11 PE=4 SV=1 CANONICAL=A5WUJ5-1" }, "isoforms": [ { "isoform_ac": "A5WUJ5-1", "url": "https://www.uniprot.org/uniprotkb/A5WUJ5/entry#A5WUJ5-1", "sequence": { "sequence": "MGQFLDSLLLLVALCSISECVQRQYHFINEMKTWTEAQRYCREKYTDLATVDNMNDMIQLMKSVKVNDRGVWIGLQRKWQWSSGDPALFLHWGNEQPDGADECAFMRNGQWEDGKCNDSWIFVCYNMSRGLVFVNQAMTWRAAQSYCRQNHTDLVSVRNQNESQQLEKFINDSHKFASEVWIGLFRDSWQWSDRSNYSFSYWNNQEPNDYGGKENCTVVQPKTEGRWNDIVCNNLFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYKVMNVVKLASTEAVWLGLRHSCALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRSGAVQSGGSQTWISRPETHKLNFICRNY", "length": 362, "header": "tr|A5WUJ5-1|A5WUJ5_DANRE Isoform 1 of Uncharacterized protein LOC100003110 precursor OS=Danio rerio OX=7955 GN=si:dkey-83f18.11 PE=4 SV=1 CANONICAL=A5WUJ5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "A5WUJ5", "url": "https://www.uniprot.org/uniprotkb/A5WUJ5" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] } ], "pathway": [ { "id": "dre:100003110", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003110", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1N7C8-1", "protein_name": "CLECT_1 and CLECT domain-containing protein isoform X1", "gene_name": "si:ch211-282j17.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYSSLLLIALCSISECVQHQYYYINVNKTWTEAQRYCREKYTDLATIDNMNELNNMNKLVKSENNGATEYVWTGLQRMSVYKWHWSSGDPALLLNWASGQPAGSDDCAVMRNGQWFDEPCSKTWIFICYNTNTGLVFVDQLMNWRAAQSYCRQNHIDLVSVRNQNESQQLEKFINDRNSSGSAVWIGLFRDTWQWSDQSNSSFRYWNTAEPNNAGGIQNCIGMNQNAQGRWHDISCTGSFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHNYCSMNMWLWVNGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHRLNFICTNY", "length": 370 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1NE49-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-83f18.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQSLFFPLLLIALCSISECVQRQYHFINENKNWTEAQRYCREKYTDLATVDNMNDMIQLNKSVNNVNNQNIYIGLQKTNVSKWHWSSGDLVLFLNWASGEPNNSYNCGTIKNGQWFAESCNNTCFFICYNMSRGLVFVNQNMNWTVAQSYCRQNHIDLVTVRNQNESQQLEKFINDRNSSGSAVWIGLFRDTWQWSDQSNSSFRYWAANFKDSSYSAAIQPNISGQWADYSSNYNQFPFVCHEDKLIVIQQTKSWSEALRYCRQNHVDLVSVQSVEMQYEVMNVVKLASTEAVWLGLRHSCALGIWFWVSGQTVCYQYWAPGNGTSEEDCEPTVRSGAVQSGGDQTWISRPEIDKLNFICRNY", "length": 364 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1P3G7-1", "protein_name": "Uncharacterized protein LOC555551 isoform 1 precursor", "gene_name": "si:dkey-88n24.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQSLYFPLHLIALCSISECVQRQYHFINENKNWTEAQRYCREKYTDLATVDNMNDLIQLKKSANNEGVQNIWIGLQRTGVYKWYWSSGDPALFLNWASGEPAGSEECAVMRNGQWIVWLCSNVSFFICNNTSTGLVFVNQSMTWREAQSYCRQNHIDLVSVRNQNENQQLEKFINDRNSSGSAVWIGLFRDTWQWLDQSNSSFRYWYPGEPNNYGGHEDCAVIGKNTQRGWADVPCDSRQIPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHHYCSMNMWLWVSGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGNQTWISLPESHRLNFICTNY", "length": 368 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RF17-1", "protein_name": "C-type mannose receptor 2", "gene_name": "si:ch211-225k7.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQSLYFPLLLIALCSISECVQRQYHFINEKKTWTEAQRYCREKYTDLATVDNMNDTTELMKSVYDVRLWIGLQRKWQWSSGGPALFLNWGYNQPDGSDECAFMKNGVWHDGKCSDTWIFVCYNMSRGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNENQQLENFINDRNSSGSAVWIGLFRDSWQWSDQSTYSFSYWNNQEPNNVGGNENCTVLMENTQGHWADISCDRQFPFVCHEDKLIVIQQNLSWSEALRYCRQHHVDLVSVQSVEMQYEVMNVVKLASTEAVWLGLRFSHILGIWFWVSGETVYYRNWAPGNGTSEEDCEPTVRSGAVQSGGNQTWISRPETDKLNFICSRYE", "length": 361 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YZA0-1", "protein_name": "C-type mannose receptor 2", "gene_name": "si:ch211-282j17.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQALFFLQLVALCSVSECVQHQYYFINQVKNWTEAQRYCRENYTDLATADNMNDTIELIKPVNKARAQNIWIGLRKTSVYTWHWSSGDTVLFLNWASGQPASSNNCTVMRNGHWFDWSCSATCFFICYNTNSGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNESQQLEKFINDRNSSGSAVWIGLFRDTWQWSDHSNSSFRYWNTAEPNNYGGDENCSVIETNAQRGWADNPCHYQFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHNYCSMNMWLWVNGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHTLNFICTNY", "length": 366 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q208-1", "protein_name": "Macrophage mannose receptor 1", "gene_name": "si:ch211-225k7.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYFPLLLIALCSISECVQRQYHFIHEKKTWTEAQRYCREKYTDLATVDNMNDTIQLMKSVNDERIWIGLQRKWQWSSGDPALFLNWAYRQPDGKDECAFMINGEWHDGACSNTLFFICYNMSRGLVFVDQMMNWRDAQSYCRQNHTDLVTVRNQNESQQLEKFINDSNSSGSAVWIGLFRDWQWSDQSNYSFRYWDTNQPDNQGGTENCAVITQNVQGRWNDISCDHQFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLRFSHILGIWYWVSGETVFYQNWAPGNGTSEEDCEPTVRSGAVQSGGSQTWISRPETDRLNFICSRYG", "length": 360 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TYY6-1", "protein_name": "C-type mannose receptor 2", "gene_name": "si:dkey-192d15.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQAQYILLLIALCSISECVQRQYHFINEKKNLTEAQRYCRENYTDLATVDNMNNMIQLNKSVNDERVWIGLQRTSVYKWHWSSGDPALFLNWASGQPVGSDNCTYMTNGQWIVGPCSAISPFICYNMSRGLVFVNQTVNWRAAQSYCRQNHTDLVIVRNQNESQQLEQFINDRQLSGGAIWIGLFRDPWQWSDQSNSSFRYWKTTEPDNYGGIENCTVIEENAQGRWADYPCYWKMPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHHYCSMNMWLWLTGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHRLNFICTN", "length": 362 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LXV6-1", "protein_name": "C-type lectin domain containing 20A", "gene_name": "Clec20a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWYCQEHYTDLADLQSMNSLVSVMVVYSYTSSVQAWIGLFYDVRISGLSWSSGSVFTMPTWSKLPVFQDGVCATLYSWYGVPALGAASCTGQKPFICYFDPAVGHRISLVSPLKDLTTLPEEAEVKIGGQTFIRIKQTMTWLSALTYCRHHYTDLADLQRVTDKDKDSLKPVINGDDAWIGLYFSVKINHLTWSSDQGSSIPEWLQEMPMFGQGLCAGIRTFANHPPQIYALLCPDLKPFICFNDPSIGHRQSAEMPSLIDTSSPRVTQHSKVPTRTTSRPNTGTSTDSTDASQVLDSASWIPRQVSHEPTAVSSGTCGFRTCDTTTPASTTVGLTALQSQGMVSIRPVATSAYPGETKERTTEASVSGSTAEVQGNWTSVPAAWNPDTSTGTAGSLPGTTTAMTTVEGGIYKGDTTSATEAQHLCSPKYPESKKKAAASESEHSFGILKADFAIPALRDPEEMKDQLLSEIQEVLKLILGHEEFTLKWIGSEVNKK", "length": 497 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58G2Y2-1", "protein_name": "C-type mannose receptor 2-like isoform X1", "gene_name": "si:dkey-28d5.15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKHSEAFSLKQISEMAQKLQFFLLLIALCSISECVQRQYHFINEMKTWTEAQRYCREKYTDLATVDSMNDTTELMKIVNNVRLWIGLERKWQWSSGDPVLFLNWGDKQPDGKDECAFMRNGEWHDWPCNKDCFFVCYNRSRGLVFVNERKNWTDAQSHCRLHYTDLVSVRNQNENQQLEKFINDSPKPEPGSDVWIGLFRDSWQWSDQSNYSFSNWKLGEPNNVGDHENCTAVEKDAQGQWIDISCDHQLPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYEVMSDVKKASTEAVWLGLRFSHILGIWFWVSGETVCYQNWAPGNGTSEENCEATVRSGAVQSGGDQTWISRPETHKLNFICSKY", "length": 377 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58H6E4-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkeyp-94g1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKSKKEKSSTVSQWVAQSPHSKKVTGSSPSRRGSGVMHESLFMLLLLSGLLRMNSELYRDYYFINIRMSWPEAQSYCRAKYTDLATAESTDDVNRLLNSVGAQYNGSVWIGLKRGTQKRWGWSYGDNTIAQYTAWSNGEPSSTNECGFLAYGNWRTYNCSDLIYFACYNGTGYTMLTMWMNWTDAQSYCRKHYIDLPTIHNSTELAQINSAVSYNAWLWIGLFKDSWEWSDKWGWFFRYWAVGQPSPSAGSSDCVGMSTTNFGKWASYSCGLQQPFICYGGTKFPYIYQYVNKSMTWPDAQSYCRARFTDLATVDTMDDVNRLVNIVDPGFSGSVWIGLQNGGQNRWIWSLGNGVLSTYSFWNPGEPSGDGDCGSSTYGNWSDESCSTVLPFLCFDDHTGFAIINTAMTWRDAQSYCRHYHTDLATIDSVDQQHMISTQSTLWIGLFLDSWGWSDQDILSFRYWAPDQPPLSSVSGDCAGLSTADFGQWAQYSCNLQQNFICYGDDSLINKQIVHIKLSCKDKCTPNDPTLQTAFLNKINEKLRSLGLERKSKISWKQSEDEEVFHEETYPPTNY", "length": 575 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WUG5-1", "protein_name": "Uncharacterized protein LOC558654 precursor", "gene_name": "si:ch211-225k7.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYFPLLLIALCSISECVQRQYHFINENKTWTEAQRYCREKYTDLATVDNMNDTIQLNKSVNDVRLWIGLQRKWQWSSGDPELFLNWESGQPDGKDECAFMRHGKWHDGKCSDTWFVICYNMSRGLVFVNQTMNWRAAQSYCRQNHIDLVSVRNQNESQQLEKFINDSIPSRSDVWIGLFRDWQWSDQSNYSFSYWNTNEPNNYGNNENCTVLKENTNGHWADISCDCQFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYKVMNVVKLASTGAVWLGLRHSCALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRSGAVQSGGDQTWISRPETDRLNFICRNY", "length": 359 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F6PDD5-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-81n2.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYIPLLLIALCSISECVQRQYHFINEGRNQTEAQKYCREKYTDLATVDNMSDMNQLIKSVNNGGVENIWIGLQRTSVYKWHWSSGDPVLFLNWTSGEPAGSNECTVMHNGQWINEACSNTRFFICYNMSTGLVFVDQMMNWRDAQSYCRQNHTDLVSVRNQNENQQLEKFINDRNSSGAEVWIGLFRDSWQWSDQSNSSFRYWNTGEPNNVEESCAVIGKNPQRGWADVLCDGRKIPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYKVMNVVKLASTEAVWLGLRHSCALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRSGAVQSGGNQTWISRPETDRLNFICRNY", "length": 366 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1L8A7-1", "protein_name": "Uncharacterized protein LOC555932 precursor", "gene_name": "si:ch73-335d12.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYLSLLLIALCSISECVQRQYHFINKNKTWTEAQRYCREKYTDLATVDNMNDMIQMNKSVKVNDGYAWIGLQRTSVYKWHWSSGDSVLFLNWASGQPAGGDNCTVMRNGKWFVEPCSDAWTFICYNMSRGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNENQQLEKFINDRNSSGSAVWIGLFRDTWQWSDQSNSSFRYWDTIEPNNAGGHENCAVIYLYNLKQWNDILCDRQYAFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHNFCSMNMWLWLSGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHRLNFICTNY", "length": 366 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZU45-1", "protein_name": "Putative C-type lectin domain family 20 member A", "gene_name": "CLEC20A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPRALLLSFCAAALQLVSSKRDLVLVKEALSWYDAQQHCRLHYTDLADLQPSGLWKLYSLMTSTPAWIGLFFDASTSGLRWSSGSTFTALEWGQKLPEFGVGFCATLYTWLKLPSIGAASCTAQKPFLCYCDPDVGHLISTKPSLSLTTSPKPAVVQISGQTFMRFDQVMTWSSALLYCRSHHTDLADLQMVTDETGKEALRSIMSETEAWIGLYLNANSGSLSWSSDLGASIPSWLQVPMMVRGLCTALGIYMTYSPKVYSVNCSSLLPFFCFYDSSTGHRASAELPPLFHTSPTEMTEETTPRPGRAVASVGSGTDRRDTAAATEAQHLSSESKEKTSAQKSGHPFGILKADFTISTLMDPEEMKDQFLRQIQEVLKLTLGHEQFRLKWVSFEVNKK", "length": 400 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-496", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-496#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 215, "end_pos": 217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5WUJ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUJ5" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 125, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 126, "end_pos": 128 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 171, "end_pos": 173 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 215, "end_pos": 217 }, { "start_pos": 251, "end_pos": 253 }, { "start_pos": 322, "end_pos": 324 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PQ50-1", "uniprot_ac": "A0A8M9PQ50", "uniprot_id": "A0A8M9PQ50_DANRE", "mass": { "chemical_mass": 29547.0, "monoisotopic_mass": 29547.0 }, "refseq": { "ac": "XP_021324381", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324381" }, "gene_names": [ { "name": "LOC100002633", "type": "recommended", "evidence": [ { "id": "A0A8M9PQ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ50" } ] }, { "name": "LOC100002633", "type": "synonym", "evidence": [ { "id": "XP_021324381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324381" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PQ50", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ50/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021324381", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324381" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324381" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQ50", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ50" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100002633", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ50", "locus": {} } ], "crossref": [ { "id": "A0A8M9PQ50", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PQ50", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000099804", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000099804", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100002633", "url": "https://www.ncbi.nlm.nih.gov/gene/100002633", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100002633", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100002633", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KDMGRCG", "url": "https://omabrowser.org/oma/group/KDMGRCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A0G2KGI0", "url": "https://www.orthodb.org/?gene=A0A0G2KGI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PQ50", "url": "https://www.orthodb.org/?gene=A0A8M9PQ50", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_021324381", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324381", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0G2KGI0", "url": "https://www.uniprot.org/uniprotkb/A0A0G2KGI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": 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"https://www.uniprot.org/uniprotkb/A0A8M9PQ50/entry#A0A0G2KGI0-1", "sequence": { "sequence": "MKDMGRCGHVALCAILLFYCSIVTASSHLSVKRKDGVSEVNMTSVLQTMEMDFSNQTQPPVNNTSTESTPHTNTTAGIVVNSTTPMEDISFSNNVTASQNKSDVSHVQNHTAANTTTPTILLPFTTHKSPTSLSATIHTMTTASSRTTHSSNSESRADLSSTATQNAQTTTNSSSPIQARAHMDTPSELNIGDDDSNKVSTDPLLAGLVSAFVVVAAIVSVLVFLKFRNTNSGPEFRRLQDLPMDDMMEDAPLSMYSY", "length": 258, "header": "tr|A0A0G2KGI0-1|A0A8M9PQ50_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100002633 PE=4 SV=1 CANONICAL=A0A8M9PQ50-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PQ50-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ50/entry#A0A8M9PQ50-1", "sequence": { "sequence": "MKDMGRCGHVALCAILLFYCSIVTVSAATRILQSNSGCVTNSTSSHLSVKRKDGVSEVNMTSVLQTMEMDFSNQTQPPVNNTSTESTPHTNTTAGIVVNSTTPMEDISFSNNVTASQNKSDVSHVQNHTAANTTTPTILLPFTTHKSPTSLSATIHTMTTASSRTTHSSNSESRADLSSTATQNAQTTTNSSSPIQARAHMDTPSELNIGDDDSNKVSTDPLLAGLVSAFVVVAAIVSVLVFLKFRNTNSGPEFRRLQDLPMDDMMEDAPLSMYSY", "length": 276, "header": "tr|A0A8M9PQ50-1|A0A8M9PQ50_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100002633 PE=4 SV=1 CANONICAL=A0A8M9PQ50-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100002633", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100002633", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, 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"end_pos": 120 }, { "start_pos": 127, "end_pos": 129 }, { "start_pos": 132, "end_pos": 134 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 59, "end_pos": 61 }, { "start_pos": 73, "end_pos": 75 }, { "start_pos": 80, "end_pos": 82 }, { "start_pos": 81, "end_pos": 83 }, { "start_pos": 91, "end_pos": 93 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A3KGZ3-1", "uniprot_ac": "A3KGZ3", "uniprot_id": "A3KGZ3_DANRE", "mass": { "chemical_mass": 49885.0, "monoisotopic_mass": 49885.0 }, "refseq": { "ac": "XP_005171902", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171902" }, "gene_names": [ { "name": "zgc:113436", "type": "synonym", "evidence": [ { "id": "XP_005171902", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171902" }, { "id": "A3KGZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KGZ3" } ] } ], "protein_names": [ { "name": "Gypsy retrotransposon integrase-like protein 1", "type": "recommended", "evidence": [ { "id": "A3KGZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KGZ3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005171902", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171902" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005171902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171902" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KGZ3", "url": "https://www.uniprot.org/uniprotkb/A3KGZ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A3KGZ3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050220-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050220-6", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000056204", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000056204", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "503528", "url": "https://www.ncbi.nlm.nih.gov/gene/503528", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "FPQTMNP", "url": "https://omabrowser.org/oma/group/FPQTMNP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A0R4II69", "url": "https://www.orthodb.org/?gene=A0A0R4II69", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A3KGZ3", "url": "https://www.orthodb.org/?gene=A3KGZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR37984", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37984", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR37984:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR37984:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005171902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171902", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0R4II69", "url": "https://www.uniprot.org/uniprotkb/A0A0R4II69", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0R4II69-1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4II69-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KGZ3", "url": "https://www.uniprot.org/uniprotkb/A3KGZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KGZ3-1", "url": "https://www.uniprot.org/uniprotkb/A3KGZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050220-6", "url": "https://zfin.org/ZDB-GENE-050220-6", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLSVDSLPVAEEEVVESSSNRLGDIYTFVAEGCYPQTMNPIRKKNLKRYAQKFIIDDGRLYYVGPKKEEKREVVIEAERKRQIFLECHFNDIGHHLGQKKTVHRIQSKYYWLGIVKDVVDWIKVCETCQHAERSKNLARTVRPIKVDGPWEILAIEIIGPFPGTVHGGNTHIVIITDYYSKWVEAFPVQKKDGLCVARCISSSVCRFGPSKTIFCSQNADFCEEVTKQLCERWNITVRVLSVDQPQRNALYDRSCNLLRDTIKQMVVEKQVEWDDFLDPILAVFRTSVNPTTKFTPHFLMFNRKASISCETKFDPLICYQDQEENIRNEDEANSFLSSMQDQQNNVKQMVITNMNVAYRQEKKNAKRKSRNMPSITLTVAEPLFSSEESPSAKKLKESLYLSFPVETVLTTVQNVPDAKKNGLDYPLTDSDMH", "length": 433, "header": "tr|A3KGZ3-1|A3KGZ3_DANRE Isoform 1 of Gypsy retrotransposon integrase-like protein 1 OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A3KGZ3-1" }, "isoforms": [ { "isoform_ac": "A0A0R4II69-1", "url": "https://www.uniprot.org/uniprotkb/A3KGZ3/entry#A0A0R4II69-1", "sequence": { "sequence": "MTSDTTWVRRRLYTGFRIKVCETCQHAERSKNLARTVRPIKVDGPWEILAIEIIGPFPGTVHGGNTHIVIITDYYSKWVEAFPVQKKDGLCVARCISSSVCRFGPSKTIFCSQNADFCEEVTKQLCERWNITVRVLSVDQPQRNALYDRSCNLLRDTIKQMVVEKQVEWDDFLDPILAVFRTSVNPTTKFTPHFLMFNRKASISCETKFDPLICYQDQEENIRNEDEANSFLSSMQDQQNNVKQMVITNMNVAYRQEKKNAKRKSRNMPSITLTVAEPLFSSEESPSAKKLKESLYLSFPVETVLTTVQNVPDAKKNGLDYPLTDSDMH", "length": 329, "header": "tr|A0A0R4II69-1|A3KGZ3_DANRE Computationally mapped isoform of Gypsy retrotransposon integrase-like protein 1 OS=Danio rerio OX=7955 GN= PE=4 SV=2 CANONICAL=A3KGZ3-1" }, "locus": {} }, { "isoform_ac": "A3KGZ3-1", "url": "https://www.uniprot.org/uniprotkb/A3KGZ3/entry#A3KGZ3-1", "sequence": { "sequence": "MLSVDSLPVAEEEVVESSSNRLGDIYTFVAEGCYPQTMNPIRKKNLKRYAQKFIIDDGRLYYVGPKKEEKREVVIEAERKRQIFLECHFNDIGHHLGQKKTVHRIQSKYYWLGIVKDVVDWIKVCETCQHAERSKNLARTVRPIKVDGPWEILAIEIIGPFPGTVHGGNTHIVIITDYYSKWVEAFPVQKKDGLCVARCISSSVCRFGPSKTIFCSQNADFCEEVTKQLCERWNITVRVLSVDQPQRNALYDRSCNLLRDTIKQMVVEKQVEWDDFLDPILAVFRTSVNPTTKFTPHFLMFNRKASISCETKFDPLICYQDQEENIRNEDEANSFLSSMQDQQNNVKQMVITNMNVAYRQEKKNAKRKSRNMPSITLTVAEPLFSSEESPSAKKLKESLYLSFPVETVLTTVQNVPDAKKNGLDYPLTDSDMH", "length": 433, "header": "tr|A3KGZ3-1|A3KGZ3_DANRE Isoform 1 of Gypsy retrotransposon integrase-like protein 1 OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A3KGZ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis.", "journal": "Genome Res.", "date": "2003", "authors": "Lo Jane, Lee Sorcheng, Xu Min, Liu Feng, Ruan Hua, Eun Alvin, He Yawen, Ma Weiping, Wang Weefuen, Wen Zilong, Peng Jinrong", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4II69", "url": "https://www.uniprot.org/uniprotkb/A0A0R4II69" } ], "reference": [ { "type": "PubMed", "id": "12618376", "url": "https://glygen.org/publication/PubMed/12618376" } ] } ], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A3KGZ3", "url": "https://www.uniprot.org/uniprotkb/A3KGZ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A3KGZ3", "url": "https://www.uniprot.org/uniprotkb/A3KGZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A3KGZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KGZ3" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 304, "start_aa": "Arg", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PLD5-1", "uniprot_ac": "A0A8M9PLD5", "uniprot_id": "A0A8M9PLD5_DANRE", "mass": { "chemical_mass": 169700.0, "monoisotopic_mass": 169700.0 }, "refseq": { "ac": "XP_021325719", "name": "actin remodeling regulator NHS isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325719" }, "gene_names": [ { "name": "nhsa", "type": "recommended", "evidence": [ { "id": "A0A8M9PLD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5" } ] }, { "name": "nhsa", "type": "synonym", "evidence": [ { "id": "XP_021325719", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325719" } ] } ], "protein_names": [ { "name": "Actin remodeling regulator NHS isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PLD5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5/entry#names_and_taxonomy" } ] }, { "name": "actin remodeling regulator NHS isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325719", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325719" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325719.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325719" } ] } ], "disease": [ { "disease_id": "DOID:0060599", "recommended_name": { "id": "DOID:0060599", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060599", "name": "Nance-Horan syndrome", "description": "A syndrome that has_material_basis_in mutation in the NHS gene on chromosome Xp22 and is characterized by congenital cataract leading to profound vision loss, characteristic dysmorphic features and dental anomalies." }, "synonyms": [ { "id": "MONDO:0010545", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010545", "name": "Nance-Horan syndrome", "description": "A syndrome characterized by the association in male patients of congenital cataracts with microcornea, dental anomalies and facial dysmorphism." }, { "id": "MONDO:0010545", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010545", "name": "Nance-Horan syndrome", "description": "" }, { "id": "MONDO:0010545", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010545", "name": "nance-horan syndrome, X-linked dominant", "description": "" }, { "id": "MONDO:0010545", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010545", "name": "Mesiodens cataract syndrome", "description": "" }, { "id": "MONDO:0010545", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010545", "name": "NHS", "description": "" }, { "id": "MONDO:0010545", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010545", "name": "cataract X-linked with Hutchinsonian teeth", "description": "" }, { "id": "MONDO:0010545", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010545", "name": "cataract dental syndrome", "description": "" }, { "id": "MIM:302350", "resource": "MIM", "url": "https://www.omim.org/entry/302350", "name": "Nance-Horan syndrome", "description": "Nance-Horan syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060599", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060599" } ] }, { "disease_id": "DOID:0110272", "recommended_name": { "id": "DOID:0110272", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110272", "name": "cataract 40", "description": "A cataract that has_material_basis_in mutation in the NHS gene on chromosome Xp22." }, "synonyms": [ { "id": "DOID:0110272", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110272", "name": "CTRCT40", "description": "" }, { "id": "DOID:0110272", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110272", "name": "cataract 40 X-linked", "description": "" }, { "id": "DOID:0110272", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110272", "name": "cataract 40 with or without microcornea", "description": "" }, { "id": "MONDO:0010544", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010544", "name": "cataract 40", "description": "Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the NHS gene." }, { "id": "MONDO:0010544", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010544", "name": "CTRCT40", "description": "" }, { "id": "MONDO:0010544", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010544", "name": "NHS early-onset non-syndromic cataract", "description": "" }, { "id": "MONDO:0010544", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010544", "name": "cataract 40", "description": "" }, { "id": "MONDO:0010544", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010544", "name": "cataract 40 with or without microcornea", "description": "" }, { "id": "MONDO:0010544", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010544", "name": "cataract type 40", "description": "" }, { "id": "MONDO:0010544", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010544", "name": "early-onset non-syndromic cataract caused by mutation in NHS", "description": "" }, { "id": "MONDO:0010544", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010544", "name": "cataract 40, X-linked", "description": "" }, { "id": "MONDO:0010544", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010544", "name": "cataract congenital X-linked", "description": "" }, { "id": "MONDO:0010544", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010544", "name": "cataract, congenital, with microcornea or slight microphthalmia", "description": "" }, { "id": "MIM:302200", "resource": "MIM", "url": "https://www.omim.org/entry/302200", "name": "Cataract 40", "description": "Cataract 40" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110272", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110272" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLD5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nhsa", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090617-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090617-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PLD5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PLD5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100150332", "url": "https://www.ncbi.nlm.nih.gov/gene/100150332", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024845", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024845", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100150332", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100150332", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M1QKA2", "url": "https://www.orthodb.org/?gene=A0A8M1QKA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PLD5", "url": "https://www.orthodb.org/?gene=A0A8M9PLD5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23039", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23039", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23039:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23039:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15273", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15273", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325719", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325719", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M1QKA2", "url": "https://www.uniprot.org/uniprotkb/A0A8M1QKA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1QKA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1QKA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLD5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PTR0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PTR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PX19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PX19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PX19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PX19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMH2", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMH2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMH6", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMH6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMH9", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMH9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090617-1", "url": "https://zfin.org/ZDB-GENE-090617-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPFSKRIVEPQWLCRRSDTEDELLQDLCAFSNVALSRTLRQLSDLAKHACSLFQELENELLFTNRRVCALRDTVNRIQENTEALDPKQEAVPLSNLDIESKLSGHYQAPWHLQRNVFLPSTRPACVEELHRHAKQSLRAMYRDQQQRQQESERERRVTISISMLPSVPSYPSPRAHRRRQQRDTHLSTERTERDTETQTTQTQFQSTRSSSPTECCHFSPWSRKVTPPGDSDSELVALGHWPKCPIPNVPSTLDKQTNWAGLLPLPTPEEKMKTDSQVINSCIVPINVTEEGASASSPSAISAFLRVGFDREASVRCSLVHSQSVLQRRRKLRRRKTITGIPRRVQQDLDSDESPVARERTVIVHTNPEIGQEDLTLSRLKTKDSGCQTEEILIAGAAPSRRRIRAQRGQCMTVSLSHSTGNISSLPDNSDAMFTASAGSHLRSRSLPREGGRLVDEGHDDSDEEEDEEELSPFEAEDFLPVPGEHILKDDEESTDDQTIPEGQHNSLKFKQHAGSTDHEWLERGRSRLPRKADMGSCEISSSSDTFSSPIHSISNAGVLTSQMDHKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNAATNTNDDSTGFIIDPYPGDRLQGLRSHRTGSFTSTATDMLDDAGVSTASEGEWSYPQYRHNIPCHPDFSPEHSRAENILECPSFTSIATFESLTDRPPSEKADTTSHYSVDAEGYYTSMHFDCGLKGSKSFTYNYASVDQQQADYGHQTNTLGRHSLSLRKPKVKPSPPKRSSSLRKLSSHVGPPTEKNEPKIAGDQNKSMSSGERTHNMGLNGTSLSQLESEEPMGAWGVESSAEIPDVALFGSTETHSFKDEGAVQSDYADLWLLNDLKSNDPYRSLSNSSTATGTTVIECIKSQESSESQTSQSGSRATTPSLPSVECEFRLPSPEKLVGLASPSSGYSSQSETPTSSLPSAFFPNAHPMSPTGGKRKPKVPERKSSLASLQQNSSKRELELPIIPPTHLDLSALPNVSKPSVHKNQMHILHHSKKKAAETKRECQASSVSSDDLPVSGALAITPTILRSVQLRAVGKSGEGSHDQPITDTATRPKCPTVTIITPPTHNKSHESRKPPPYRPLLTEPTSQDNCESLFTPVNGLAAKNTPSHFGARNRYDRLAPSPLWSMTAFKAQTEPVNLDEVISENSQEAAEEKIPSDYLFAQSSMEVQQNQSLRSEPNDRSPGQNGVAKRSDSLDQVPDIVNQRSETLQAYKISGAGEESVTSGVPTRSASQEYVEEGSTPDTEDYFSRESTPSDPSVSPLIDESKTEDDSVFLSPSKSRTTEDLFAMIHRSKRKMLGRKDSSETLVRGRLAVVSGNGPATNPTTPPSTPSIPASPSAQTGSQKTPGPIYRSVKKSSTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPIAPKSPGELLLEGSRPLEEPLSPIQQQFLEGTPEQIPSPFPKSFAEGFSMKAFPTSASARQGRSRMPPAANSSRYSTRSRLYCAPMQAISEGETENSDGSPHDDRSS", "length": 1546, "header": "tr|A0A8M9PLD5-1|A0A8M9PLD5_DANRE Isoform 1 of Actin remodeling regulator NHS isoform X1 OS=Danio rerio OX=7955 GN=nhsa PE=4 SV=2 CANONICAL=A0A8M9PLD5-1" }, "isoforms": [ { "isoform_ac": "A0A8M1QKA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5/entry#A0A8M1QKA2-1", "sequence": { "sequence": "MPFSKRIVEPQWLCRRSDTEDELLQDLCAFSNVALSRTLRQLSDLAKHACSLFQELENELLFTNRRVCALRDTVNRIQENTEALDPKQEAVPLSNLDIESKLSGHYQAPWHLQRNVFLPSTRPACVEELHRHAKQSLRAMYRDQQQRQQESERERRVTISISMLPSVPSYPSPRAHRRRQQRDTHLSTERTERDTETQTTQTQFQSTRSSSPTECCHFSPWSRKVTPPGDSDSELVALGHWPKCPIPNVPSTLDKQTNWAGLLPLPTPEEKMKTDSQVINSCIVPINVTGVGFDREASVRCSLVHSQSVLQRRRKLRRRKTITGIPRRVQQDLDSDESPVARERTVIVHTNPEIGQEDLTLSRLKTKDSGCQTEEILIAGAAPSRRRIRAQRGQCMTVSLSHSTGNISSLPDNSDAMFTASAGSHLRSRSLPREGGRLVDEGHDDSDEEEDEEELSPFEAEDFLPVPGEHILKDDEESTDDQTIPEGQHNSLKFKQHAGSTDHEWLERGRSRLPRKADMGSCEISSSSDTFSSPIHSISNAGVLTSQMDHKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNAATNTNDDSTGFIIDPYPGDRLQGLRSHRTGSFTSTATDMLDDAGVSTASEGEWSYPQYRHNIPCHPDFSPEHSRAENILECPSFTSIATFESLTDRPPSEKADTTSHYSVDAEGYYTSMHFDCGLKGSKSFTYNYASVDQQQADYGHQTNTLGRHSLSLRKPKVKPSPPKRSSSLRKLSSHVGPPTEKNEPKIAGDQNKSMSSGERTHNMGLNGTSLSQLESEEPMGAWGVESSAEIPDVALFGSTETHSFKDEGAVQSDYADLWLLNDLKSNDPYRSLSNSSTATGTTVIECIKSQESSESQTSQSGSRATTPSLPSVECEFRLPSPEKLVGLASPSSGYSSQSETPTSSLPSAFFPNAHPMSPTGGKRKPKVPERKSSLASLQQNSSKRELELPIIPPTHLDLSALPNVSKPSVHKNQMHILHHSKKKAAETKRECQASSVSSDDLPVSGALAITPTILRSVQLRAVGKSGEGSHDQPITDTATRPKCPTVTIITPPTHNKSHESRKPPPYRPLLTEPTSQDNCESLFTPVNGLAAKNTPSHFGARNRYDRLAPSPLWSMTAFKAQTEPVNLDEVISENSQEAAEEKIPSDYLFAQSSMEVQQNQSLRSEPNDRSPGQNGVAKRSDSLDQVPDIVNQRSETLQAYKISGAGEESVTSGVPTRSASQEYVEEGSTPDTEDYFSRESTPSDPSVSPLIDESKTEDDSVFLSPSKSRTTEDLFAMIHRSKRKMLGRKDSSETLVRGRLAVVSGNGPATNPTTPPSTPSIPASPSAQTGSQKTPGPIYRSVKKSSTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPIAPKSPGELLLEGSRPLEEPLSPIQQQFLEGTPEQIPSPFPKSFAEGFSMKAFPTSASARQGRSRMPPAANSSRYSTRSRLYCAPMQAISEGETENSDGSPHDDRSS", "length": 1530, "header": "tr|A0A8M1QKA2-1|A0A8M9PLD5_DANRE Computationally mapped isoform of Actin remodeling regulator NHS isoform X1 OS=Danio rerio OX=7955 GN=nhsa PE=4 SV=2 CANONICAL=A0A8M9PLD5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PLD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5/entry#A0A8M9PLD5-1", "sequence": { "sequence": "MPFSKRIVEPQWLCRRSDTEDELLQDLCAFSNVALSRTLRQLSDLAKHACSLFQELENELLFTNRRVCALRDTVNRIQENTEALDPKQEAVPLSNLDIESKLSGHYQAPWHLQRNVFLPSTRPACVEELHRHAKQSLRAMYRDQQQRQQESERERRVTISISMLPSVPSYPSPRAHRRRQQRDTHLSTERTERDTETQTTQTQFQSTRSSSPTECCHFSPWSRKVTPPGDSDSELVALGHWPKCPIPNVPSTLDKQTNWAGLLPLPTPEEKMKTDSQVINSCIVPINVTEEGASASSPSAISAFLRVGFDREASVRCSLVHSQSVLQRRRKLRRRKTITGIPRRVQQDLDSDESPVARERTVIVHTNPEIGQEDLTLSRLKTKDSGCQTEEILIAGAAPSRRRIRAQRGQCMTVSLSHSTGNISSLPDNSDAMFTASAGSHLRSRSLPREGGRLVDEGHDDSDEEEDEEELSPFEAEDFLPVPGEHILKDDEESTDDQTIPEGQHNSLKFKQHAGSTDHEWLERGRSRLPRKADMGSCEISSSSDTFSSPIHSISNAGVLTSQMDHKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNAATNTNDDSTGFIIDPYPGDRLQGLRSHRTGSFTSTATDMLDDAGVSTASEGEWSYPQYRHNIPCHPDFSPEHSRAENILECPSFTSIATFESLTDRPPSEKADTTSHYSVDAEGYYTSMHFDCGLKGSKSFTYNYASVDQQQADYGHQTNTLGRHSLSLRKPKVKPSPPKRSSSLRKLSSHVGPPTEKNEPKIAGDQNKSMSSGERTHNMGLNGTSLSQLESEEPMGAWGVESSAEIPDVALFGSTETHSFKDEGAVQSDYADLWLLNDLKSNDPYRSLSNSSTATGTTVIECIKSQESSESQTSQSGSRATTPSLPSVECEFRLPSPEKLVGLASPSSGYSSQSETPTSSLPSAFFPNAHPMSPTGGKRKPKVPERKSSLASLQQNSSKRELELPIIPPTHLDLSALPNVSKPSVHKNQMHILHHSKKKAAETKRECQASSVSSDDLPVSGALAITPTILRSVQLRAVGKSGEGSHDQPITDTATRPKCPTVTIITPPTHNKSHESRKPPPYRPLLTEPTSQDNCESLFTPVNGLAAKNTPSHFGARNRYDRLAPSPLWSMTAFKAQTEPVNLDEVISENSQEAAEEKIPSDYLFAQSSMEVQQNQSLRSEPNDRSPGQNGVAKRSDSLDQVPDIVNQRSETLQAYKISGAGEESVTSGVPTRSASQEYVEEGSTPDTEDYFSRESTPSDPSVSPLIDESKTEDDSVFLSPSKSRTTEDLFAMIHRSKRKMLGRKDSSETLVRGRLAVVSGNGPATNPTTPPSTPSIPASPSAQTGSQKTPGPIYRSVKKSSTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPIAPKSPGELLLEGSRPLEEPLSPIQQQFLEGTPEQIPSPFPKSFAEGFSMKAFPTSASARQGRSRMPPAANSSRYSTRSRLYCAPMQAISEGETENSDGSPHDDRSS", "length": 1546, "header": "tr|A0A8M9PLD5-1|A0A8M9PLD5_DANRE Isoform 1 of Actin remodeling regulator NHS isoform X1 OS=Danio rerio OX=7955 GN=nhsa PE=4 SV=2 CANONICAL=A0A8M9PLD5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PTR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5/entry#A0A8M9PTR0-1", "sequence": { "sequence": "MALGCCIPLRSKALSNLDIESKLSGHYQAPWHLQRNVFLPSTRPACVEELHRHAKQSLRAMYRDQQQRQQESERERRVTISISMLPSVPSYPSPRAHRRRQQRDTHLSTERTERDTETQTTQTQFQSTRSSSPTECCHFSPWSRKVTPPGDSDSELVALGHWPKCPIPNVPSTLDKQTNWAGLLPLPTPEEKMKTDSQVINSCIVPINVTEEGASASSPSAISAFLRVGFDREASVRCSLVHSQSVLQRRRKLRRRKTITGIPRRVQQDLDSDESPVARERTVIVHTNPEIGQEDLTLSRLKTKDSGCQTEEILIAGAAPSRRRIRAQRGQCMTVSLSHSTGNISSLPDNSDAMFTASAGSHLRSRSLPREGGRLVDEGHDDSDEEEDEEELSPFEAEDFLPVPGEHILKDDEESTDDQTIPEGQHNSLKFKQHAGSTDHEWLERGRSRLPRKADMGSCEISSSSDTFSSPIHSISNAGVLTSQMDHKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNAATNTNDDSTGFIIDPYPGDRLQGLRSHRTGSFTSTATDMLDDAGVSTASEGEWSYPQYRHNIPCHPDFSPEHSRAENILECPSFTSIATFESLTDRPPSEKADTTSHYSVDAEGYYTSMHFDCGLKGSKSFTYNYASVDQQQADYGHQTNTLGRHSLSLRKPKVKPSPPKRSSSLRKLSSHVGPPTEKNEPKIAGDQNKSMSSGERTHNMGLNGTSLSQLESEEPMGAWGVESSAEIPDVALFGSTETHSFKDEGAVQSDYADLWLLNDLKSNDPYRSLSNSSTATGTTVIECIKSQESSESQTSQSGSRATTPSLPSVECEFRLPSPEKLVGLASPSSGYSSQSETPTSSLPSAFFPNAHPMSPTGGKRKPKVPERKSSLASLQQNSSKRELELPIIPPTHLDLSALPNVSKPSVHKNQMHILHHSKKKAAETKRECQASSVSSDDLPVSGALAITPTILRSVQLRAVGKSGEGSHDQPITDTATRPKCPTVTIITPPTHNKSHESRKPPPYRPLLTEPTSQDNCESLFTPVNGLAAKNTPSHFGARNRYDRLAPSPLWSMTAFKAQTEPVNLDEVISENSQEAAEEKIPSDYLFAQSSMEVQQNQSLRSEPNDRSPGQNGVAKRSDSLDQVPDIVNQRSETLQAYKISGAGEESVTSGVPTRSASQEYVEEGSTPDTEDYFSRESTPSDPSVSPLIDESKTEDDSVFLSPSKSRTTEDLFAMIHRSKRKMLGRKDSSETLVRGRLAVVSGNGPATNPTTPPSTPSIPASPSAQTGSQKTPGPIYRSVKKSSTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPIAPKSPGELLLEGSRPLEEPLSPIQQQFLEGTPEQIPSPFPKSFAEGFSMKAFPTSASARQGRSRMPPAANSSRYSTRSRLYCAPMQAISEGETENSDGSPHDDRSS", "length": 1467, "header": "tr|A0A8M9PTR0-1|A0A8M9PLD5_DANRE Computationally mapped isoform of Actin remodeling regulator NHS isoform X1 OS=Danio rerio OX=7955 GN=nhsa PE=4 SV=2 CANONICAL=A0A8M9PLD5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PX19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5/entry#A0A8M9PX19-1", "sequence": { "sequence": "MPFSKRIVEPQWLCRRSDTEDELLQDLCAFSNVALSRTLRQLSDLAKHACSLFQELENELLFTNRRVCALRDTVNRIQENTEALDPKQEAVPLSNLDIESKLSGHYQAPWHLQRNVFLPSTRPACVEELHRHAKQSLRAMYRDQQQRQQESERERRVTISISMLPSVPSYPSPRAHRRRQQRDTHLSTERTERDTETQTTQTQVTPPGDSDSELVALGHWPKCPIPNVPSTLDKQTNWAGLLPLPTPEEKMKTDSQVINSCIVPINVTEEGASASSPSAISAFLRVGFDREASVRCSLVHSQSVLQRRRKLRRRKTITGIPRRVQQDLDSDESPVARERTVIVHTNPEIGQEDLTLSRLKTKDSGCQTEEILIAGAAPSRRRIRAQRGQCMTVSLSHSTGNISSLPDNSDAMFTASAGSHLRSRSLPREGGRLVDEGHDDSDEEEDEEELSPFEAEDFLPVPGEHILKDDEESTDDQTIPEGQHNSLKFKQHAGSTDHEWLERGRSRLPRKADMGSCEISSSSDTFSSPIHSISNAGVLTSQMDHKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNAATNTNDDSTGFIIDPYPGDRLQGLRSHRTGSFTSTATDMLDDAGVSTASEGEWSYPQYRHNIPCHPDFSPEHSRAENILECPSFTSIATFESLTDRPPSEKADTTSHYSVDAEGYYTSMHFDCGLKGSKSFTYNYASVDQQQADYGHQTNTLGRHSLSLRKPKVKPSPPKRSSSLRKLSSHVGPPTEKNEPKIAGDQNKSMSSGERTHNMGLNGTSLSQLESEEPMGAWGVESSAEIPDVALFGSTETHSFKDEGAVQSDYADLWLLNDLKSNDPYRSLSNSSTATGTTVIECIKSQESSESQTSQSGSRATTPSLPSVECEFRLPSPEKLVGLASPSSGYSSQSETPTSSLPSAFFPNAHPMSPTGGKRKPKVPERKSSLASLQQNSSKRELELPIIPPTHLDLSALPNVSKPSVHKNQMHILHHSKKKAAETKRECQASSVSSDDLPVSGALAITPTILRSVQLRAVGKSGEGSHDQPITDTATRPKCPTVTIITPPTHNKSHESRKPPPYRPLLTEPTSQDNCESLFTPVNGLAAKNTPSHFGARNRYDRLAPSPLWSMTAFKAQTEPVNLDEVISENSQEAAEEKIPSDYLFAQSSMEVQQNQSLRSEPNDRSPGQNGVAKRSDSLDQVPDIVNQRSETLQAYKISGAGEESVTSGVPTRSASQEYVEEGSTPDTEDYFSRESTPSDPSVSPLIDESKTEDDSVFLSPSKSRTTEDLFAMIHRSKRKMLGRKDSSETLVRGRLAVVSGNGPATNPTTPPSTPSIPASPSAQTGSQKTPGPIYRSVKKSSTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPIAPKSPGELLLEGSRPLEEPLSPIQQQFLEGTPEQIPSPFPKSFAEGFSMKAFPTSASARQGRSRMPPAANSSRYSTRSRLYCAPMQAISEGETENSDGSPHDDRSS", "length": 1525, "header": "tr|A0A8M9PX19-1|A0A8M9PLD5_DANRE Computationally mapped isoform of Actin remodeling regulator NHS isoform X1 OS=Danio rerio OX=7955 GN=nhsa PE=4 SV=2 CANONICAL=A0A8M9PLD5-1" }, "locus": {} }, { "isoform_ac": "A0AC58IMH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5/entry#A0AC58IMH2-1", "sequence": { "sequence": "MPFSKRIVEPQWLCRRSDTEDELLQDLCAFSNVALSRTLRQLSDLAKHACSLFQELENELLFTNRRVCALRDTVNRIQENTEALDPKQEAVPLSNLDIESKLSGHYQAPWHLQRNVFLPSTRPACVEELHRHAKQSLRAMYRDQQQRQQESERERRVTISISMLPSVPSYPSPRAHRRRQQRDTHLSTERTERDTETQTTQTQVTPPGDSDSELVALGHWPKCPIPNVPSTLDKQTNWAGLLPLPTPEEKMKTDSQVINSCIVPINVTGVGFDREASVRCSLVHSQSVLQRRRKLRRRKTITGIPRRVQQDLDSDESPVARERTVIVHTNPEIGQEDLTLSRLKTKDSGCQTEEILIAGAAPSRRRIRAQRGQCMTVSLSHSTGNISSLPDNSDAMFTASAGSHLRSRSLPREGGRLVDEGHDDSDEEEDEEELSPFEAEDFLPVPGEHILKDDEESTDDQTIPEGQHNSLKFKQHAGSTDHEWLERGRSRLPRKADMGSCEISSSSDTFSSPIHSISNAGVLTSQMDHKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNAATNTNDDSTGFIIDPYPGDRLQGLRSHRTGSFTSTATDMLDDAGVSTASEGEWSYPQYRHNIPCHPDFSPEHSRAENILECPSFTSIATFESLTDRPPSEKADTTSHYSVDAEGYYTSMHFDCGLKGSKSFTYNYASVDQQQADYGHQTNTLGRHSLSLRKPKVKPSPPKRSSSLRKLSSHVGPPTEKNEPKIAGDQNKSMSSGERTHNMGLNGTSLSQLESEEPMGAWGVESSAEIPDVALFGSTETHSFKDEGAVQSDYADLWLLNDLKSNDPYRSLSNSSTATGTTVIECIKSQESSESQTSQSGSRATTPSLPSVECEFRLPSPEKLVGLASPSSGYSSQSETPTSSLPSAFFPNAHPMSPTGGKRKPKVPERKSSLASLQQNSSKRELELPIIPPTHLDLSALPNVSKPSVHKNQMHILHHSKKKAAETKRECQASSVSSDDLPVSGALAITPTILRSVQLRAVGKSGEGSHDQPITDTATRPKCPTVTIITPPTHNKSHESRKPPPYRPLLTEPTSQDNCESLFTPVNGLAAKNTPSHFGARNRYDRLAPSPLWSMTAFKAQTEPVNLDEVISENSQEAAEEKIPSDYLFAQSSMEVQQNQSLRSEPNDRSPGQNGVAKRSDSLDQVPDIVNQRSETLQAYKISGAGEESVTSGVPTRSASQEYVEEGSTPDTEDYFSRESTPSDPSVSPLIDESKTEDDSVFLSPSKSRTTEDLFAMIHRSKRKMLGRKDSSETLVRGRLAVVSGNGPATNPTTPPSTPSIPASPSAQTGSQKTPGPIYRSVKKSSTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPIAPKSPGELLLEGSRPLEEPLSPIQQQFLEGTPEQIPSPFPKSFAEGFSMKAFPTSASARQGRSRMPPAANSSRYSTRSRLYCAPMQAISEGETENSDGSPHDDRSS", "length": 1509, "header": "tr|A0AC58IMH2-1|A0AC58IMH2_DANRE Computationally mapped isoform of Actin remodeling regulator NHS isoform X4 OS=Danio rerio OX=7955 GN=nhsa PE=4 SV=1 CANONICAL=A0A8M9PLD5-1" }, "locus": {} }, { "isoform_ac": "A0AC58IMH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5/entry#A0AC58IMH6-1", "sequence": { "sequence": "MALGCCIPLRSKALSNLDIESKLSGHYQAPWHLQRNVFLPSTRPACVEELHRHAKQSLRAMYRDQQQRQQESERERRVTISISMLPSVPSYPSPRAHRRRQQRDTHLSTERTERDTETQTTQTQVTPPGDSDSELVALGHWPKCPIPNVPSTLDKQTNWAGLLPLPTPEEKMKTDSQVINSCIVPINVTGVGFDREASVRCSLVHSQSVLQRRRKLRRRKTITGIPRRVQQDLDSDESPVARERTVIVHTNPEIGQEDLTLSRLKTKDSGCQTEEILIAGAAPSRRRIRAQRGQCMTVSLSHSTGNISSLPDNSDAMFTASAGSHLRSRSLPREGGRLVDEGHDDSDEEEDEEELSPFEAEDFLPVPGEHILKDDEESTDDQTIPEGQHNSLKFKQHAGSTDHEWLERGRSRLPRKADMGSCEISSSSDTFSSPIHSISNAGVLTSQMDHKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNAATNTNDDSTGFIIDPYPGDRLQGLRSHRTGSFTSTATDMLDDAGVSTASEGEWSYPQYRHNIPCHPDFSPEHSRAENILECPSFTSIATFESLTDRPPSEKADTTSHYSVDAEGYYTSMHFDCGLKGSKSFTYNYASVDQQQADYGHQTNTLGRHSLSLRKPKVKPSPPKRSSSLRKLSSHVGPPTEKNEPKIAGDQNKSMSSGERTHNMGLNGTSLSQLESEEPMGAWGVESSAEIPDVALFGSTETHSFKDEGAVQSDYADLWLLNDLKSNDPYRSLSNSSTATGTTVIECIKSQESSESQTSQSGSRATTPSLPSVECEFRLPSPEKLVGLASPSSGYSSQSETPTSSLPSAFFPNAHPMSPTGGKRKPKVPERKSSLASLQQNSSKRELELPIIPPTHLDLSALPNVSKPSVHKNQMHILHHSKKKAAETKRECQASSVSSDDLPVSGALAITPTILRSVQLRAVGKSGEGSHDQPITDTATRPKCPTVTIITPPTHNKSHESRKPPPYRPLLTEPTSQDNCESLFTPVNGLAAKNTPSHFGARNRYDRLAPSPLWSMTAFKAQTEPVNLDEVISENSQEAAEEKIPSDYLFAQSSMEVQQNQSLRSEPNDRSPGQNGVAKRSDSLDQVPDIVNQRSETLQAYKISGAGEESVTSGVPTRSASQEYVEEGSTPDTEDYFSRESTPSDPSVSPLIDESKTEDDSVFLSPSKSRTTEDLFAMIHRSKRKMLGRKDSSETLVRGRLAVVSGNGPATNPTTPPSTPSIPASPSAQTGSQKTPGPIYRSVKKSSTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPIAPKSPGELLLEGSRPLEEPLSPIQQQFLEGTPEQIPSPFPKSFAEGFSMKAFPTSASARQGRSRMPPAANSSRYSTRSRLYCAPMQAISEGETENSDGSPHDDRSS", "length": 1430, "header": "tr|A0AC58IMH6-1|A0AC58IMH6_DANRE Computationally mapped isoform of Actin remodeling regulator NHS isoform X7 OS=Danio rerio OX=7955 GN=nhsa PE=4 SV=1 CANONICAL=A0A8M9PLD5-1" }, "locus": {} }, { "isoform_ac": "A0AC58IMH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5/entry#A0AC58IMH9-1", "sequence": { "sequence": "MALGCCIPLRSKALSNLDIESKLSGHYQAPWHLQRNVFLPSTRPACVEELHRHAKQSLRAMYRDQQQRQQESERERRVTISISMLPSVPSYPSPRAHRRRQQRDTHLSTERTERDTETQTTQTQFQSTRSSSPTECCHFSPWSRKVTPPGDSDSELVALGHWPKCPIPNVPSTLDKQTNWAGLLPLPTPEEKMKTDSQVINSCIVPINVTGVGFDREASVRCSLVHSQSVLQRRRKLRRRKTITGIPRRVQQDLDSDESPVARERTVIVHTNPEIGQEDLTLSRLKTKDSGCQTEEILIAGAAPSRRRIRAQRGQCMTVSLSHSTGNISSLPDNSDAMFTASAGSHLRSRSLPREGGRLVDEGHDDSDEEEDEEELSPFEAEDFLPVPGEHILKDDEESTDDQTIPEGQHNSLKFKQHAGSTDHEWLERGRSRLPRKADMGSCEISSSSDTFSSPIHSISNAGVLTSQMDHKEDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNAATNTNDDSTGFIIDPYPGDRLQGLRSHRTGSFTSTATDMLDDAGVSTASEGEWSYPQYRHNIPCHPDFSPEHSRAENILECPSFTSIATFESLTDRPPSEKADTTSHYSVDAEGYYTSMHFDCGLKGSKSFTYNYASVDQQQADYGHQTNTLGRHSLSLRKPKVKPSPPKRSSSLRKLSSHVGPPTEKNEPKIAGDQNKSMSSGERTHNMGLNGTSLSQLESEEPMGAWGVESSAEIPDVALFGSTETHSFKDEGAVQSDYADLWLLNDLKSNDPYRSLSNSSTATGTTVIECIKSQESSESQTSQSGSRATTPSLPSVECEFRLPSPEKLVGLASPSSGYSSQSETPTSSLPSAFFPNAHPMSPTGGKRKPKVPERKSSLASLQQNSSKRELELPIIPPTHLDLSALPNVSKPSVHKNQMHILHHSKKKAAETKRECQASSVSSDDLPVSGALAITPTILRSVQLRAVGKSGEGSHDQPITDTATRPKCPTVTIITPPTHNKSHESRKPPPYRPLLTEPTSQDNCESLFTPVNGLAAKNTPSHFGARNRYDRLAPSPLWSMTAFKAQTEPVNLDEVISENSQEAAEEKIPSDYLFAQSSMEVQQNQSLRSEPNDRSPGQNGVAKRSDSLDQVPDIVNQRSETLQAYKISGAGEESVTSGVPTRSASQEYVEEGSTPDTEDYFSRESTPSDPSVSPLIDESKTEDDSVFLSPSKSRTTEDLFAMIHRSKRKMLGRKDSSETLVRGRLAVVSGNGPATNPTTPPSTPSIPASPSAQTGSQKTPGPIYRSVKKSSTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPIAPKSPGELLLEGSRPLEEPLSPIQQQFLEGTPEQIPSPFPKSFAEGFSMKAFPTSASARQGRSRMPPAANSSRYSTRSRLYCAPMQAISEGETENSDGSPHDDRSS", "length": 1451, "header": "tr|A0AC58IMH9-1|A0AC58IMH9_DANRE Computationally mapped isoform of Actin remodeling regulator NHS isoform X6 OS=Danio rerio OX=7955 GN=nhsa PE=4 SV=1 CANONICAL=A0A8M9PLD5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1379, "start_aa": "Thr", "end_pos": 1379, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1379", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 267, "start_aa": "Thr", "end_pos": 267, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr267", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100150332", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100150332", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JXJ0-1", "protein_name": "NHS actin remodeling regulator", "gene_name": "Nhs", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTSPDGRIPGEPARGPAARPGRTGGRISAPGERSTGGLPRAEPEPERTPGEASLGAAPHRNPTGCSTTRSPGHTAVSNLDIESKLSVYYRAPWHQQRNIFLPVTRPPCVEELHRHARQSLQALRREHRSRSDRREQRAAAPVPIAAPPLPAYPPAHSQRRREAKDRHLLTFNSTRSPSPTECCHMAPWSRKSHSPEDEDTDVMLGQRPKNPIHNVPSTLDKQTNWNKALPLPTPEEKMKQDAQVISSCIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVARERNVIVHTNPDPSNTVNRRSGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAGNISALADKGDTMFTPVVSSRTRSRSLPREGNRGGDAEPKVGAKPSAFEEGEHFVGDHERAPNDCGEAPSSSSTQEHQPTLGLACSQHLHSPQQKLSERGRSRLSRMAADSGSCDISSNSDTFGSPIHCISTASVLLSSHMDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNTAPNANEDASVFVTEQYNDHLDKVRGHRTNSFTSTVADLLDDPNNSNTSDSEWNYLHHHHDASCRQDFSPEHPKADSLGCPSFTSMGTYDSFLEKSPSDKADTSSHFSVDTEGYYTSMHFDCGLKGNKTYVCHYAGLGPENGQGVGVPPALPDCAWQEYLDHRRQGRPSISFRKPKAKPTPPKRSSSLRKSDGNADISEKKEPKISSGQHLPHSSREMKLPLDFSNTPSRVENANLPAKLDSSWISQSEHAIKEPQLDTTDISPFKDEGAESTHYADLWLLNDLKTNDPYRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEYKLASPEKLAGLASPSSGYSSQSETPTSSFPTAFFSGPQSPGGSKRKPKVPERKSSLQQPSLKDGALSLSKDFELPIIPPSHLDLSALHVLNKPFHHRHPLHVFTHKQNTVGDMLRSNPPPSLAITPTVLKSVNLRSISKSDEVKQKEGNNTDLPYLEENAVTVASVASLSPSKARSHTAKKSISRQYSAEDTLMPFLDSSVGEMGPEKHLEKNPTFDGKSHGNPETVASASSNLPDSNVMKDQIQMESELIPESIPSKNCGFSTGFQRVSASRPSDLGNKMIQYGASPDGAIQQGQKVPSGVGEEGGKPESVDGITLQANSSTRVTDISSQYKHQRVVSRHHDKVPVTIRHESEPSTVNSFPEKCSEQENIASGISPKSASDNSGAEETQGRMDETALKESSPSDDPIASPLSEDSQAEAEGVFVSPNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRVPLGSSSSSANSVTSPSSNVTTGISQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPVLPKPPGEFTAESPQSPDDTHQSTPGTEALSPLSPCSPRVNAEGFSSKNFATSASARVGRSRAPPVASSSRYSVRCRLYNTPMQAISEGETENSDGSPHDDRSSQSST", "length": 1537 }, "evidence": [ { "id": "RGD:1561818", "url": "https://alliancegenome.org/gene/RGD:1561818#orthology", "database": "AGR" }, { "id": "HGNC:7820", "url": "https://alliancegenome.org/gene/HGNC:7820#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090617-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090617-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PVJ7-1", "protein_name": "Actin remodeling regulator NHS isoform X1", "gene_name": "nhsb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPFAKRIVEPQLLVRHPIPNDEGLLFEDLCSITNVALSRTLRQLSDLSKHACSLFQELENEIVSTNQRVWALQNKIGKIQQTASALDPKMEAVRFRSISIAVSNLDIESKLTSHYQAPWHQQHNLFHTCTRPACLEELHRHAKLNLRALHRDQQQRQRSTSRERSRVTISISVAPPMPTFPSTHKLRRREQRGRHSRMERSVRESDVQTIQRKERPAKDSEFKPVLRKYQRSRSPSPVQCCYFIPWIRKAGTNTETDGELQVMSHRPKCPVPNAPTTLDKQTNWSKALPLPTPEERIKNDSQVISSCIIPINVSGVGFDREASARCSLVHSQSVLQRRRKLRRRKTITGIPKRVQQDMDSDESPVARERTVIIHANPHKSHEWHEELSLSGRVLHTKDSGCQTDDFLITAPSRRRIRAQRGQGIPASLSHSTGNITSLPDRSDTVYAAASATRVRSRSLPREGGRLLDEDQDDSDDDDDEDDDEDDEEEDEELSPYEAEDFLPGPGQRIPKDEEESTDDQAMPELQFGSLKRMQHSESPDHTWIERGRSRLPRKVDMGSCEISSSSDTFSSPIHSASTTGVLGSQIDHKEDHQSSSGNWSGSSSTCPSQTSETLPPAASPPLTGSSHCDSELSLNTGSHVIDDNTGFIIDPYHIDKPQGQGQRSNSFTSSATDQMDDAGVSTASDGEWNCAQDQQDQSCTQDFSPKRSREDESGVSCPSYSSGETYESFSDQASARKSEMHYIVDTEGFYSSMHFDSGLKGSRSYYNYAAIDPDCGPSGNIAPGMTEYPQPEYRATRTLGRPCLSLRKPKAKPPPPKRSSSLKETSSDVNVPEQNEPKITCELPLPLSSREMKLQLDLADSAGHLETAGLESLGAWGVENVRDMLDCSSPFSSSDTHSFKDEGAVQADYADLWLHNDLKSNDPYRSLSNSSSATGTTVIECIKSPERSETHTCQPRSRPSSPTLPPPESEFKLASPEKLAGLASPSSGYSSQSETPTSSFPSAFFPGPLSPTSGKRKPKVPERKSSLCSLQQQQLSVRDPGISCRRETDFYAIPPSHLDLSALHSKHFPHRNQMHILHQNKQKAAIAAAAAAEARSAAAAAAEARSAAAAAAEARSAATAAAAAEACTAATASTKESATNTAPISAHLAITPTVLRSVQLRSICRPSDGNQGLDQDSSNLITRPKCPTIITDAPSSSNRHNRKPPAYKPPAAQVCDSQIPLVENIVFPQEEVRVRQERFGPGTYWAMTAFRTPVDPNCEKEVSLKRSSQCFQQEQDSRRCLDVQKTLSPERLKQDLNQLSRPDPSTQSMCLASTMPPPAYSEIQRSNFVLCNSPDKVPVSTQEASHSYTISDVQGREEDYETSGVATRSASQDIREEESTPDTEDYFSKDSTPSDNSSSPLTDDSRLDDDVFPSPNKLRTTEDLFAMIHRSKRKVLGRKDSGEVSGKGRPVVPPVTTPVSNPTVCPVIPAPPVPSNNSQRASGPIYRSAKKSSTSSEEFKLLLLKKGSRTDSSYRMSATEILKSPITPKTQAELLLEAMRQPEEIPLPQLDSTSSGDPLPSPFPKANSEGFSPKTLTMSAASRQGRSRIPPAANSSRYSTRSRLYTAPMQAISEGETENSDGSPHDDRSS", "length": 1630 }, "evidence": [ { "id": "RGD:1561818", "url": "https://alliancegenome.org/gene/RGD:1561818#orthology", "database": "AGR" }, { "id": "HGNC:7820", "url": "https://alliancegenome.org/gene/HGNC:7820#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6T4R5-1", "protein_name": "Actin remodeling regulator NHS", "gene_name": "NHS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPFAKRIVEPQWLCRQRRPAPGPAVDASGGSAEPPPPLQPPGRRDLDEVEAPGPEEPARAVPAPSGLPPPPPPLPAPADQTQPPHGEASVAGEESTAGIPEAAPAAGEASSAAAAAAVLLMLDLCAVSNAALARVLRQLSDVARHACSLFQELESDIQLTHRRVWALQGKLGGVQRVLSTLDPKQEAVPVSNLDIESKLSVYYRAPWHQQRNIFLPATRPPCVEELHRHARQSLQALRREHRSRSDRREQRAAAPLSIAAPPLPAYPPAHSQRRREFKDRHFLTFNSTRSPSPTECCHMTPWSRKSHPPEDEDTDVMLGQRPKNPIHNIPSTLDKQTNWSKALPLPTPEEKMKQDAQVISSCIIPINVTGVGFDREASIRCSLVHSQSVLQRRRKLRRRKTISGIPRRVQQEIDSDESPVARERNVIVHTNPDPSNTVNRISGTRDSECQTEDILIAAPSRRRIRAQRGQSIAASLSHSAGNISALADKGDTMFTPAVSSRTRSRSLPREGNRGGDAEPKVGAKPSAYEEGESFVGDHERTPNDFSEAPSSPSAQDHQPTLGLACSQHLHSPQHKLSERGRSRLSRMAADSGSCDISSNSDTFGSPIHCISTAGVLLSSHMDQKDDHQSSSGNWSGSSSTCPSQTSETIPPAASPPLTGSSHCDSELSLNTAPHANEDASVFVTEQYNDHLDKVRGHRANSFTSTVADLLDDPNNSNTSDSEWNYLHHHHDASCRQDFSPERPKADSLGCPSFTSMATYDSFLEKSPSDKADTSSHFSVDTEGYYTSMHFDCGLKGNKSYVCHYAALGPENGQGVGASPGLPDCAWQDYLDHKRQGRPSISFRKPKAKPTPPKRSSSLRKSDGNADISEKKEPKISSGQHLPHSSREMKLPLDFANTPSRMENANLPTKQEPSWINQSEQGIKEPQLDASDIPPFKDEVAESTHYADLWLLNDLKTNDPYRSLSNSSTATGTTVIECIKSPESSESQTSQSESRATTPSLPSVDNEFKLASPEKLAGLASPSSGYSSQSETPTSSFPTAFFSGPLSPGGSKRKPKVPERKSSLQQPSLKDGTISLSKDLELPIIPPTHLDLSALHNVLNKPFHHRHPLHVFTHNKQNTVGETLRSNPPPSLAITPTILKSVNLRSINKSEEVKQKEENNTDLPYLEESTLTTAALSPSKIRPHTANKSVSRQYSTEDTILSFLDSSAVEMGPDKLHLEKNSTFDVKNRCDPETITSAGSSLLDSNVTKDQVRTETEPIPENTPTKNCAFPTEGFQRVSAARPNDLDGKIIQYGPGPDETLEQVQKAPSAGLEEVAQPESVDVITSQSDSPTRATDVSNQFKHQFVMSRHHDKVPGTISYESEITSVNSFPEKCSKQENIASGISAKSASDNSKAEETQGNVDEASLKESSPSDDSIISPLSEDSQAEAEGVFVSPNKPRTTEDLFAVIHRSKRKVLGRKDSGDMSVRSKSRAPLSSSSSSASSITSPSSNVTTPNSQRSPGLIYRNAKKSNTSNEEFKLLLLKKGSRSDSSYRMSATEILKSPILPKPPGELTAESPQSTDDAHQGSQGAEALSPLSPCSPRVNAEGFSSKSFATSASARVGRSRAPPAASSSRYSVRCRLYNTPMQAISEGETENSDGSPHDDRSSQSST", "length": 1651 }, "evidence": [ { "id": "RGD:1561818", "url": "https://alliancegenome.org/gene/RGD:1561818#orthology", "database": "AGR" }, { "id": "HGNC:7820", "url": "https://alliancegenome.org/gene/HGNC:7820#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090617-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090617-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VE13-1", "protein_name": "Wiskott-Aldrich syndrome protein family member", "gene_name": "gukh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPFVQRVVQPVNVAQATAASLGHASGRFHCTPGKCRNNNCINKQSPDVEVPNGHGSPTSLTRVLVHQAPEDQPVPPAPAPMKKLKHHVEFLSTSPTRHQSQSLPNSRHPSQQRPALGRIASAPQSPTAGSSKVVSGHEFDSISNITLSNALRQLASLVLIASDIFDDLQRDLQAVGERAGRVQRKIAAVERRVCAYDPKTVTVPESDLLTFAQRKHHFETDKSFQQELFTGETRPLSVRQLYTEAGKELPVATGATATALASLAHSQSLIPSRSISFNGEVLSSDHEVLQLNGSTDTEDHLLCVSDFGNANRKLRTRIDAEIEIRLPAAIEDLRKWTSSEALGDVTVTPDCMHHVDTSVSTSLAIGENGILTPALSPSVLSADAVDALYAQNLSQAADSSRHNHHTQALIPNDINKDVPLNHRLPSPEEQTKQIALKYPAEVISVNTSGKHFQRMCAARKSTSGGYAGGATAGSSSSTSPENAGQTEGNNLDDNVQTVSRRSRSRKVRGKRRNTIAGIDQKEIQDAANGNGESKNASNATSPVAPAQQAETTSSDAKKSKKFGRSKSSDILKKESAALPYDKGKSTLTRLNSLKQWGRNRFKFMHRTGELGDQLDTSGCSSQNSSAEKADSHHGSPAGDNSKRDIDDECVVHHLVAQKSESRFSHERKPSYSSSEKSISVSSSGQLRGRLQLSSGPMAAAHVKMRETATLNRQRRNGLHALAGKEEQPHSSSGNWSASSESGRASIGSEITMQPKSSASSTSLNVSSFQPGGAGSGPPSSMLSRRRFLNTSASSSVTSEGTATPELQAEAGAYPGHLDDETSSAYSCDTEGYYTSFHMDSGLRTLKEEEPSVMPGTPLQTSLHTSSYSFGSQSNQTVLNAESEYELFGRGSTSTTTSSAGTVCTALMSGAASGPDVPERSSSLGKHSGQSRSQSTSASSSTLERSYSSSTIGSTLERTGTIKRNVKMSPTKAGGEVTEKDDQQDQDQQQQLEFSESSDLEGVERIERIKQKTALTSKRIPSMCIITPTTSDDDEHQTNDPNRTLTSLTIDVEHGEQDEDEAEQKTPTNSKDHNLNELKQTPTKALSGMFEKLRVKLVPGKSSPAKNQMQPKPANSSAVNDDELYDLAGEYVTIADISNNNNNNKNIGRRNTGMGIYYSNDIVSKRVEPSTSAVSEYVSLNELPQHLRRHAVSSRSAPAAESESCAQQQLPVEPAAATSQPPPLPLGGRTQGVGDGVPMYAEIGELSEEKPLASAANRRLRPNAEGKLVYDSDSLKRRKGAHTTFAPGPYVKETESALHSAESAAAAIASSQDPSAASGAISSTKSAKLLLLTSGGLISGNRKVANVRPIVAKSPLSRNVSEMATYQATSYQDQKQLLANRTNPFYETIAAPVANLMMPSPSGKSNSSTGSTATSSSSSASGQSGEEGYQRFSNIYEQVQPAPSTQPQEDATATPFQRSAPIYWTLQNRRSQPRPQPAGNVTCRDDLYATPIRRADRLPRPVAAAAATAAEGNRSNISPIVPRNRSGAFLTSTPTRSGEGERDSENTQLPPMKQPSRNWTDDAPERLNTCADRIGQSKTTLMDFKKLLLAKSAKASPVQRKVSAVELLKKPAQATATPPVVKPSGPGQKVASAGSKPTINTSLKLLDLSGSPKTFANRRMLRQGQFGSPSKTFAPKMRGPVNMVAAAAAPPRTDIMSTTIPEANSEEDHSNTSGGSRASSEAGETVPSSFDLKRNFFLQTEENNFMRGELKPSFARSNGAAGGGSTEGVNKYVAAPVANPPLPSFETAL", "length": 1788 }, "evidence": [ { "id": "RGD:1561818", "url": "https://alliancegenome.org/gene/RGD:1561818#orthology", "database": "AGR" }, { "id": "HGNC:7820", "url": "https://alliancegenome.org/gene/HGNC:7820#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLD5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5" } ], "pmid": "" }, { "name": "lens development in camera-type eye", "id": "GO:0002088", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002088", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLD5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLD5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1001, "end_pos": 1003, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1024, "end_pos": 1026, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1116, "end_pos": 1118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1220, "end_pos": 1222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1510, "end_pos": 1512, "annotation": "n_glycosylation_sequon" }, { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 422, "end_pos": 424, "annotation": "n_glycosylation_sequon" }, { "start_pos": 576, "end_pos": 578, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" }, { "start_pos": 895, "end_pos": 897, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 267, 1379 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1001, "end_pos": 1003 }, { "start_pos": 1024, "end_pos": 1026 }, { "start_pos": 1116, "end_pos": 1118 }, { "start_pos": 1220, "end_pos": 1222 }, { "start_pos": 1510, "end_pos": 1512 }, { "start_pos": 287, "end_pos": 289 }, { "start_pos": 422, "end_pos": 424 }, { "start_pos": 576, "end_pos": 578 }, { "start_pos": 812, "end_pos": 814 }, { "start_pos": 827, "end_pos": 829 }, { "start_pos": 895, "end_pos": 897 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PQF7-1", "uniprot_ac": "A0A8M9PQF7", "uniprot_id": "A0A8M9PQF7_DANRE", "mass": { "chemical_mass": 51984.0, "monoisotopic_mass": 51984.0 }, "refseq": { "ac": "XP_021327119", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327119" }, "gene_names": [ { "name": "LOC100001051", "type": "recommended", "evidence": [ { "id": "A0A8M9PQF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQF7" } ] }, { "name": "LOC100001051", "type": "synonym", "evidence": [ { "id": "XP_021327119", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327119" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PQF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQF7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021327119", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327119" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021327119.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021327119", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327119" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQF7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQF7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100001051", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQF7", "locus": {} } ], "crossref": [ { "id": "A0A8M9PQF7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PQF7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100001051", "url": "https://www.ncbi.nlm.nih.gov/gene/100001051", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100001051", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001051", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M1QKR8", "url": "https://www.orthodb.org/?gene=A0A8M1QKR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_021327119", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327119", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M1QKR8", "url": "https://www.uniprot.org/uniprotkb/A0A8M1QKR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1QKR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1QKR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQF7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J2E6", "url": "https://www.uniprot.org/uniprotkb/A0AC58J2E6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J2E6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J2E6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPKIMERCATEILASEKSSTIKMNNTTIIFNVLKRKKVSYIFDGLRMLARALLQTSLVLWLVQSTIQGGVRPQTGALGRLASRGPGIGAKTGVAGILGARGYGAGKAGKTSAGRYIGGAAYRPTAVRGGLKQGYGTLGYGGAANLGAGLGAGLGTGLGTGLGPAGLGLGAAYGLGNGLGAALGYPGGKLGARGYTGNGYGAQLGYGAGGYPGVGRGYGVPAGTFTGQSSKPAKLGVGPRGDQPMSQGQAGDGYGPGRFTNGQSPIGNGFPPGPGLTNGMKAQTKGAVLPSRQGTKPSNTGYGLGAAGYLGTGYTDGYGAGLGAGLYPQGVRAGKQIAGYSNGYGSEVYGTADAYGAGAAFPSVLADNVGLNGIAGLGAGGLGGAGLVMNPGVDAKSRKYGVGGVLGAAGSLPYGGQPVVSAGLGPQGKTGGYGGATYGGLPTLGPDAGLGGTGGAMEPLAGGAVGQIPYNSPVIAAGLDGEAGYPFGAEQLSLGADVSKAAAKYGTGSYAAALSTGAQALSGTQKDGSKLSGLYGNGYKG", "length": 540, "header": "tr|A0A8M9PQF7-1|A0A8M9PQF7_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100001051 PE=4 SV=2 CANONICAL=A0A8M9PQF7-1" }, "isoforms": [ { "isoform_ac": "A0A8M1QKR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQF7/entry#A0A8M1QKR8-1", "sequence": { "sequence": "MKAQTKGAVLPSRQGTKPSNTGYGLGAAGYLGTGYTDGYGAGLGAGLYPQGVRAGKQIAGYSNGYGSEVYGTADAYGAGAAFPSVLADNVGLNGIAGLGAGGLGGAGLVMNPGVDAKSRKYGVGGVLGAAGSLPYGGQPVVSAGLGPQGKTGGYGGATYGGLPTLGPDAGLGGTGGAMEPLAGGAVGQIPYNSPVIAAGLDGEAGYPFGAEQLSLGADVSKAAAKYGTGSYAAALSTGAQALSGTQKDGSKLSGLYGNGYKG", "length": 262, "header": "tr|A0A8M1QKR8-1|A0A8M9PQF7_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100001051 PE=4 SV=2 CANONICAL=A0A8M9PQF7-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PQF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQF7/entry#A0A8M9PQF7-1", "sequence": { "sequence": "MPKIMERCATEILASEKSSTIKMNNTTIIFNVLKRKKVSYIFDGLRMLARALLQTSLVLWLVQSTIQGGVRPQTGALGRLASRGPGIGAKTGVAGILGARGYGAGKAGKTSAGRYIGGAAYRPTAVRGGLKQGYGTLGYGGAANLGAGLGAGLGTGLGTGLGPAGLGLGAAYGLGNGLGAALGYPGGKLGARGYTGNGYGAQLGYGAGGYPGVGRGYGVPAGTFTGQSSKPAKLGVGPRGDQPMSQGQAGDGYGPGRFTNGQSPIGNGFPPGPGLTNGMKAQTKGAVLPSRQGTKPSNTGYGLGAAGYLGTGYTDGYGAGLGAGLYPQGVRAGKQIAGYSNGYGSEVYGTADAYGAGAAFPSVLADNVGLNGIAGLGAGGLGGAGLVMNPGVDAKSRKYGVGGVLGAAGSLPYGGQPVVSAGLGPQGKTGGYGGATYGGLPTLGPDAGLGGTGGAMEPLAGGAVGQIPYNSPVIAAGLDGEAGYPFGAEQLSLGADVSKAAAKYGTGSYAAALSTGAQALSGTQKDGSKLSGLYGNGYKG", "length": 540, "header": "tr|A0A8M9PQF7-1|A0A8M9PQF7_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100001051 PE=4 SV=2 CANONICAL=A0A8M9PQF7-1" }, "locus": {} }, { "isoform_ac": "A0AC58J2E6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQF7/entry#A0AC58J2E6-1", "sequence": { "sequence": "MLARALLQTSLVLWLVQSTIQGGVRPQTGALGRLASRGPGIGAKTGVAGILGARGYGAGKAGKTSAGRYIGGAAYRPTAVRGGLKQGYGTLGYGGAANLGAGLGAGLGTGLGTGLGPAGLGLGAAYGLGNGLGAALGYPGGKLGARGYTGNGYGAQLGYGAGGYPGVGRGYGLGAAGYLGTGYTDGYGAGLGAGLYPQGVRAGKQIGYSNGYGSEVYGTADAYGAGAAFPSVLADNVGLNGIAGLGAGGLGGAGLVMNPGVDAKSRKYGVGGVLGAAGSLPYGGQPVVSAGLGPQGKTGGYGGATYGGLPTLGPDAGLGGTGGAMEPLAGGAVGQIPYNSPVIAAGLDGEAGYPFGAEQLSLGADVSKAAAKYGTGSYAAALSTGAQALSGTQKDGSKLSGLYGNGYKG", "length": 409, "header": "tr|A0AC58J2E6-1|A0AC58J2E6_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC100001051 PE=4 SV=1 CANONICAL=A0A8M9PQF7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100001051", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001051", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 24, "end_pos": 26 }, { "start_pos": 25, "end_pos": 27 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UW16-1", "uniprot_ac": "A0A8N7UW16", "uniprot_id": "A0A8N7UW16_DANRE", "mass": { "chemical_mass": 130289.0, "monoisotopic_mass": 130289.0 }, "refseq": { "ac": "XP_696330", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696330" }, "gene_names": [ { "name": "LOC567924", "type": "recommended", "evidence": [ { "id": "A0A8N7UW16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW16" } ] }, { "name": "LOC567924", "type": "synonym", "evidence": [ { "id": "XP_696330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696330" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UW16", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW16/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_696330", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696330" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_696330.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_696330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696330" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW16" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC567924", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW16", "locus": {} } ], "crossref": [ { "id": "A0A8N7UW16", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UW16", "database": "AlphaFoldDB", "categories": [] }, { "id": "567924", "url": "https://www.ncbi.nlm.nih.gov/gene/567924", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050405", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050405", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567924", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567924", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M2B2S2", "url": "https://www.orthodb.org/?gene=A0A8M2B2S2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UW16", "url": "https://www.orthodb.org/?gene=A0A8N7UW16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45652", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45652", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45652:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45652:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_696330", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696330", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B2S2", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B2S2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B2S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B2S2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UW16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UW16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERLLHSPGRTRDEHRYQTPRPSSQLLSRSAFSFGSPVPLRGNETLSEFAAKPADSFDYSSKYAGAMNLRKISEKELLQGLNDRFAGFIEKVHHLENQNRALEKEIEAIRLRAKSSTSLSKEYESELSSLREQVHEMGLQKHQIEINRQNLEDEFNTLREKYERETRGRVDAEDGISVLKKCINDAYLAKQEMDRKARALQEEIGFLKKNHESEVAEMMAQIEEGHVTAEISDFSRSDVTAALRGIRMQLEGHSGSDTRYAEERFRAQFARLTKAAEVNREALMATKAEINEHRRQLQSKNIELDSMKGVREGLERQLYDLEQRHNAEIHHYQDTIRELEFELKNAKYDMSSHLREYQDLLNVKMALDAEIYSYRKLLEGEESRYSIISDAHNSVPYIYRQSPIYTLPCVKRQGGAPRKAEPQYKFVEEIITETTREDVEISDTGSEKSGEGRVDDKPDEESSEKDAETEQEAEDPEEPAVVNGTEEAETENEDKPSDEKEDEPVEESPKGQKDADSEPTRESMPTETDIDEVGKDEETGTKGTEHKDQKVDTKGKEAPEEEDVKKTDEPIKEKELPKTEEREMPEKSEDKPSLEHKTLVNTKPNGETEVTSPKTEVAKISSQDSATAKSPEKEKETSPVQPVEKDTPKPDKHDLDKLTTEEKTSAKIAVVEEKSEKDLEDNNKQPEKPVEKKETESKEQKSEESTKDSKAAKVIDDVKTEKDDGIKSNKAEKEKVEEQSKKQEDSKTDGNVETVPIETTKEKETEKKQEDIPKEKSKTEKDDKSDSAGNANTEKDDRAAPKETEKTQQDLPKVAEGKSQPEKLQEKQEDSKSDYVKAELAKPKETEKTQEDLPKAAEEKTQPEKSQTQENSKSDSAGSTKTKKLESDATRETGKTQEDLPKAAEEKTQPEKSQTQENSKSDSAGSAKTKKLESDATKETGKTQENLPKVTEEKSQPEKPQKQENNKSDAVKPENIEHPKPTETKDNSKGMEPKLEEVKSEIKDDAKSDSVDINKTETTKPAIPKETEEKRKKEDSESVSAAESVKTSKDEAKTKEKAVDETQSTQSPKTQEPSSEAKPEQKDTNEGKGKMPEKAEEVNTVTTKGSKDVKGEDTVPKDKAGEVKAPAATKTEDKTVEKSDQVKGTEKTDSVDTKAS", "length": 1156, "header": "tr|A0A8N7UW16-1|A0A8N7UW16_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC567924 PE=4 SV=1 CANONICAL=A0A8N7UW16-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B2S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW16/entry#A0A8M2B2S2-1", "sequence": { "sequence": "MERLLHSPGRTRDEHRYQTPRPSSQLLSRSAFSFGSPVPLRGNETLSEFAAKPADSFDYSSKYAGAMNLRKISEKELLQGLNDRFAGFIEKVHHLENQNRALEKEIEAIRLRAKSSTSLSKEYESELSSLREQVHEMGLQKHQIEINRQNLEDEFNTLREKYERETRGRVDAEDGISVLKKCINDAYLAKQEMDRKARALQEEIGFLKKNHESEVAEMMAQIEEGHVTAEISDFSRSDVTAALRGIRMQLEGHSGSDTRYAEERFRAQFARLTKAAEVNREALMATKAEINEHRRQLQSKNIELDSMKGVREGLERQLYDLEQRHNAEIHHYQDTIRELEFELKNAKYDMSSHLREYQDLLNVKMALDAEIYSYRKLLEGEESRQGGAPRKAEPQYKFVEEIITETTREDVEISDTGSEKSGEGRVDDKPDEESSEKDAETEQEAEDPEEPAVVNGTEEAETENEDKPSDEKEDEPVEESPKGQKDADSEPTRESMPTETDIDEVGKDEETGTKGTEHKDQKVDTKGKEAPEEEDVKKTDEPIKEKELPKTEEREMPEKSEDKPSLEHKTLVNTKPNGETEVTSPKTEVAKISSQDSATAKSPEKEKETSPVQPVEKDTPKPDKHDLDKLTTEEKTSAKIAVVEEKSEKDLEDNNKQPEKPVEKKETESKEQKSEESTKDSKAAKVIDDVKTEKDDGIKSNKAEKEKVEEQSKKQEDSKTDGNVETVPIETTKEKETEKKQEDIPKEKSKTEKDDKSDSAGNANTEKDDRAAPKETEKTQQDLPKVAEGKSQPEKLQEKQEDSKSDYVKAELAKPKETEKTQEDLPKAAEEKTQPEKSQTQENSKSDSAGSTKTKKLESDATRETGKTQEDLPKAAEEKTQPEKSQTQENSKSDSAGSAKTKKLESDATKETGKTQENLPKVTEEKSQPEKPQKQENNKSDAVKPENIEHPKPTETKDNSKGMEPKLEEVKSEIKDDAKSDSVDINKTETTKPAIPKETEEKRKKEDSESVSAAESVKTSKDEAKTKEKAVDETQSTQSPKTQEPSSEAKPEQKDTNEGKGKMPEKAEEVNTVTTKGSKDVKGEDTVPKDKAGEVKAPAATKTEDKTVEKSDQVKGTEKTDSVDTKAS", "length": 1128, "header": "tr|A0A8M2B2S2-1|A0A8N7UW16_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC567924 PE=4 SV=1 CANONICAL=A0A8N7UW16-1" }, "locus": {} }, { "isoform_ac": "A0A8N7UW16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW16/entry#A0A8N7UW16-1", "sequence": { "sequence": "MERLLHSPGRTRDEHRYQTPRPSSQLLSRSAFSFGSPVPLRGNETLSEFAAKPADSFDYSSKYAGAMNLRKISEKELLQGLNDRFAGFIEKVHHLENQNRALEKEIEAIRLRAKSSTSLSKEYESELSSLREQVHEMGLQKHQIEINRQNLEDEFNTLREKYERETRGRVDAEDGISVLKKCINDAYLAKQEMDRKARALQEEIGFLKKNHESEVAEMMAQIEEGHVTAEISDFSRSDVTAALRGIRMQLEGHSGSDTRYAEERFRAQFARLTKAAEVNREALMATKAEINEHRRQLQSKNIELDSMKGVREGLERQLYDLEQRHNAEIHHYQDTIRELEFELKNAKYDMSSHLREYQDLLNVKMALDAEIYSYRKLLEGEESRYSIISDAHNSVPYIYRQSPIYTLPCVKRQGGAPRKAEPQYKFVEEIITETTREDVEISDTGSEKSGEGRVDDKPDEESSEKDAETEQEAEDPEEPAVVNGTEEAETENEDKPSDEKEDEPVEESPKGQKDADSEPTRESMPTETDIDEVGKDEETGTKGTEHKDQKVDTKGKEAPEEEDVKKTDEPIKEKELPKTEEREMPEKSEDKPSLEHKTLVNTKPNGETEVTSPKTEVAKISSQDSATAKSPEKEKETSPVQPVEKDTPKPDKHDLDKLTTEEKTSAKIAVVEEKSEKDLEDNNKQPEKPVEKKETESKEQKSEESTKDSKAAKVIDDVKTEKDDGIKSNKAEKEKVEEQSKKQEDSKTDGNVETVPIETTKEKETEKKQEDIPKEKSKTEKDDKSDSAGNANTEKDDRAAPKETEKTQQDLPKVAEGKSQPEKLQEKQEDSKSDYVKAELAKPKETEKTQEDLPKAAEEKTQPEKSQTQENSKSDSAGSTKTKKLESDATRETGKTQEDLPKAAEEKTQPEKSQTQENSKSDSAGSAKTKKLESDATKETGKTQENLPKVTEEKSQPEKPQKQENNKSDAVKPENIEHPKPTETKDNSKGMEPKLEEVKSEIKDDAKSDSVDINKTETTKPAIPKETEEKRKKEDSESVSAAESVKTSKDEAKTKEKAVDETQSTQSPKTQEPSSEAKPEQKDTNEGKGKMPEKAEEVNTVTTKGSKDVKGEDTVPKDKAGEVKAPAATKTEDKTVEKSDQVKGTEKTDSVDTKAS", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A8DZD4-1", "uniprot_ac": "A8DZD4", "uniprot_id": "A8DZD4_DANRE", "mass": { "chemical_mass": 41724.0, "monoisotopic_mass": 41724.0 }, "refseq": { "ac": "NP_001121866", "name": "bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121866" }, "gene_names": [ { "name": "bnipl", "type": "recommended", "evidence": [ { "id": "A8DZD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DZD4" } ] }, { "name": "bnipl", "type": "synonym", "evidence": [ { "id": "NP_001121866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121866" } ] }, { "name": "si:dkey-77n11.1", "type": "synonym", "evidence": [ { "id": "NP_001121866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121866" }, { "id": "A8DZD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DZD4" } ] } ], "protein_names": [ { "name": "BCL2/adenovirus E1B 19kD interacting protein, like", "type": "synonym", "evidence": [ { "id": "NP_001121866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121866" } ] }, { "name": "Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein", "type": "synonym", "evidence": [ { "id": "A8DZD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DZD4/entry#names_and_taxonomy" } ] }, { "name": "bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein", "type": "synonym", "evidence": [ { "id": "NP_001121866", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121866" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.2133165.1, SRR32588734.3042573.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505392, SAMEA4476731 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000016.1. On Jul 31, 2008 this sequence version replaced XP_001922156.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001121866", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121866" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8DZD4", "url": "https://www.uniprot.org/uniprotkb/A8DZD4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "bnipl", "url": "https://www.uniprot.org/uniprotkb/A8DZD4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-81", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-81", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000060435", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000060435", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": 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"Protein Classification" ] }, { "id": "A0A8M2B535", "url": "https://www.orthodb.org/?gene=A0A8M2B535", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A8DZD4", "url": "https://www.orthodb.org/?gene=A8DZD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12112", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12112", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12112:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12112:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12496", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12496", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13716", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13716", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A8DZD4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A8DZD4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001121866", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121866", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B535", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B535", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B535-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B535-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8DZD4", "url": "https://www.uniprot.org/uniprotkb/A8DZD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8DZD4-1", "url": "https://www.uniprot.org/uniprotkb/A8DZD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-81", "url": "https://zfin.org/ZDB-GENE-060503-81", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGTYSDQREAYMQNGHTENSRTSDFIPDMELREEWQDEEFPRPLPEDTHSPGDEEESAGAEGKKPVPPTSLALTGNTVRKKRLVAPTLSLTLDKTSTDRSLKSDEFEASALSPSPDDDLDMDINLEALETPSDSESYNFPESMHDLEWEDDLPRMGKASIRKPSLLEHAEMGHLELDQVDDYGRRWRHFHIGGQDYQVNMSVLEPYLQVLSHGGYYGDGSTAIIMFTSCYLPENTTEHYEYVMDNLFRYIIGTLDLMVSENYILVYLCGMAPRNKMPGIKWLRQCYMSIDRRLRKDLKGLFVVHPAWYVRALITVIKPFISEKFSRKMRFIHSLQELAEFVPVEQLQIPDCIREYDTQLNR", "length": 361, "header": "tr|A8DZD4-1|A8DZD4_DANRE Isoform 1 of Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein OS=Danio rerio OX=7955 GN=bnipl PE=4 SV=1 CANONICAL=A8DZD4-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B535-1", "url": "https://www.uniprot.org/uniprotkb/A8DZD4/entry#A0A8M2B535-1", "sequence": { "sequence": "MELREEWQDEEFPRPLPEDTHSPGDEEESAGAEGKKPVPPTSLALTGNTVRKKRLVAPTLSLTLDKTSTDRSLKSDEFEASALSPSPDDDLDMDINLEALETPSDSESYNFPESMHDLEWEDDLPRMGKASIRKPSLLEHAEMGHLELDQVDDYGRRWRHFHIGGQDYQVNMSVLEPYLQVLSHGGYYGDGSTAIIMFTSCYLPENTTEHYEYVMDNLFRYIIGTLDLMVSENYILVYLCGMAPRNKMPGIKWLRQCYMSIDRRLRKDLKGLFVVHPAWYVRALITVIKPFISEKFSRKMRFIHSLQELAEFVPVEQLQIPDCIREYDTQLNR", "length": 333, "header": "tr|A0A8M2B535-1|A8DZD4_DANRE Computationally mapped isoform of Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein OS=Danio rerio OX=7955 GN=bnipl PE=4 SV=1 CANONICAL=A8DZD4-1" }, "locus": {} }, { "isoform_ac": "A8DZD4-1", "url": "https://www.uniprot.org/uniprotkb/A8DZD4/entry#A8DZD4-1", "sequence": { "sequence": "MGTYSDQREAYMQNGHTENSRTSDFIPDMELREEWQDEEFPRPLPEDTHSPGDEEESAGAEGKKPVPPTSLALTGNTVRKKRLVAPTLSLTLDKTSTDRSLKSDEFEASALSPSPDDDLDMDINLEALETPSDSESYNFPESMHDLEWEDDLPRMGKASIRKPSLLEHAEMGHLELDQVDDYGRRWRHFHIGGQDYQVNMSVLEPYLQVLSHGGYYGDGSTAIIMFTSCYLPENTTEHYEYVMDNLFRYIIGTLDLMVSENYILVYLCGMAPRNKMPGIKWLRQCYMSIDRRLRKDLKGLFVVHPAWYVRALITVIKPFISEKFSRKMRFIHSLQELAEFVPVEQLQIPDCIREYDTQLNR", "length": 361, "header": "tr|A8DZD4-1|A8DZD4_DANRE Isoform 1 of Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein OS=Danio rerio OX=7955 GN=bnipl PE=4 SV=1 CANONICAL=A8DZD4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Hematopoietic gene expression profile in zebrafish kidney marrow.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2004", "authors": "Song Huai-Dong, Sun Xiao-Jian, Deng Min, Zhang Guo-Wei, Zhou Yi, Wu Xin-Yan, Sheng Yan, Chen Yi, Ruan Zheng, Jiang Chun-Lei, Fan Hui-Yong, Zon Leonard I, Kanki John P, Liu Ting Xi, Look A Thomas, Chen Zhu", "evidence": [ { "database": "UniProtKB", "id": "A8DZD4", "url": "https://www.uniprot.org/uniprotkb/A8DZD4" } ], "reference": [ { "type": "PubMed", "id": "15520368", "url": "https://glygen.org/publication/PubMed/15520368" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A8DZD4", "url": "https://www.uniprot.org/uniprotkb/A8DZD4" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A8DZD4", "url": "https://www.uniprot.org/uniprotkb/A8DZD4" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Transcriptome comparison reveals a genetic network regulating the lower temperature limit in fish.", "journal": "Sci. Rep.", "date": "2016", "authors": "Hu Peng, Liu Mingli, Liu Yimeng, Wang Jinfeng, Zhang Dong, Niu Hongbo, Jiang Shouwen, Wang Jian, Zhang Dongsheng, Han Bingshe, Xu Qianghua, Chen Liangbiao", "evidence": [ { "database": "UniProtKB", "id": "A8DZD4", "url": "https://www.uniprot.org/uniprotkb/A8DZD4" } ], "reference": [ { "type": "PubMed", "id": "27356472", "url": "https://glygen.org/publication/PubMed/27356472" } ] }, { "title": "Newly identified Gon4l/Udu-interacting proteins implicate novel functions.", "journal": "Sci. Rep.", "date": "2020", "authors": "Tsai SM, Chu KC, Jiang YJ", "evidence": [ { "database": "UniProtKB", "id": "A8DZD4", "url": "https://www.uniprot.org/uniprotkb/A8DZD4" } ], "reference": [ { "type": "PubMed", "id": "32848183", "url": "https://glygen.org/publication/PubMed/32848183" } ] } ], "pathway": [ { "id": "dre:100149386", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100149386", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1SSA0-1", "protein_name": "Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein", "gene_name": "BNIPL", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGTLQEAGEKTLDLGVRENAETAVPEASLRLGGLELQEEWQDEEFPRLLPEEADPSEDPENPKGDSQTAPGTPSTLALCGQRPMRKRLTAPELQLNLTEGPGDNGASSTHSVPSSPDGSSDLEVDELETPSDSEQLDSGHEFEWEDDLPRAEDPGASEAAERLGRGCVWDVAGEDGHHWRVFRTGQREQRVDMTVIEPYKKVLSHGGYHGDGLNAVILFASCYLPRSSIPNYTYVMEHLFRYMVGTLELLVAENYLLVHLSGGTNRAQVPPLSWLRQCYHTLDGRLRKNLRALVVVHATWYVKAFLALLRPFISSKFTRKIRFLNSLGELAQLISMDQVHIPEAVRQLDQDLHGSGGT", "length": 358 }, "evidence": [ { "id": "A8DZD4", "url": "https://omabrowser.org/oma/group/A8DZD4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q7Z465-1", "protein_name": "Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein", "gene_name": "BNIPL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTIQEAGKKTDVGVREIAEAPELGAALRHGELELKEEWQDEEFPRLLPEEAGTSEDPEDPKGDSQAAAGTPSTLALCGQRPMRKRLSAPELRLSLTKGPGNDGASPTQSAPSSPDGSSDLEIDELETPSDSEQLDSGHEFEWEDELPRAEGLGTSETAERLGRGCMWDVTGEDGHHWRVFRMGPREQRVDMTVIEPYKKVLSHGGYHGDGLNAVILFASCYLPRSSIPNYTYVMEHLFRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLRKNLRALVVVHATWYVKAFLALLRPFISSKFTRKIRFLDSLGELAQLISLDQVHIPEAVRQLDRDLHGSGGT", "length": 357 }, "evidence": [ { "id": "HGNC:16976", "url": "https://alliancegenome.org/gene/HGNC:16976#orthology", "database": "AGR" }, { "id": "MGI:2384749", "url": "https://alliancegenome.org/gene/MGI:2384749#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-81", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-81#orthology", "database": "AGR" }, { "id": "A8DZD4", "url": "https://omabrowser.org/oma/group/A8DZD4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99JU7-1", "protein_name": "Bcl-2/adenovirus E1B 19 kDa-interacting protein 2-like protein", "gene_name": "Bnipl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLGELELREEWQDEEFPRLLPEEPGSPGDPEDPQRGSQAGTPSSLALCGQRPMRKRLSAPEWQLSLTEGTGENGASPTRSASSSSAGSLDLEVDELETPSDSEQLDSGHEFEWEDDLPRAEGLGASEAAERLGRGCVCDVAGEDGHRWRVFRTGQREQRVDMTIIEPYKKVLSHGGYHGDGLNAVILFASCYLPRSSIPNYTYIMEHLFRYMVGTLELLVAENYLLVHLSGGTSRAQVPPLSWIRQCYRTLDRRLRKNLRALVVVHATWYVKAFLALVRPFISSKFTRKIRFLDSLGELAQLISLEQVHIPEVVRQLDRDLHGSKGT", "length": 328 }, "evidence": [ { "id": "HGNC:16976", "url": "https://alliancegenome.org/gene/HGNC:16976#orthology", "database": "AGR" }, { "id": "MGI:2384749", "url": "https://alliancegenome.org/gene/MGI:2384749#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-81", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-81#orthology", "database": "AGR" }, { "id": "A8DZD4", "url": "https://omabrowser.org/oma/group/A8DZD4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VZJ4-1", "protein_name": "CRAL-TRIO domain-containing protein", "gene_name": "anon-EST:Posey64", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLHYAESESSPSESKMDISETPTDSTGVSPLADDVLPTAPEKNILKLEQAKQDHDKEELEFKTTSALDNRILRPELLPMEAMPQRHNIIERTLANSHPLMSPTNTDSDSEPFQLKKQEKQLPRSNFPDVVPTTETVQVKNNLNQCRNKPQDAKVSLLRANSPDILSSESDADVSQYLAAVESNFQSVSLMPNGNGKKSKRSTALPGGEDISSLDSISNHSFDDDEDIEHNLASLSPSSSLIDGLDGEDDDDDCEGPELLPDHDDDLELDLEFGLATTPTPNAPASATAASTLPQYTAAEERRDSRNWQKITLPDGRTREIDMRVIEPYKRVLSHGGYLKSGGQNAIVIFCACHLPDRSRADYSYVMDNLFLYVVKTLEQLVTDDYVLIYLHGGSNRRNVPPFPWLKRCYQLLDRRLRKSLKHMYLVHPTFWIKSLVWMARPFVSTKFWRKLVYVKSLEELGMHVVVEKAAIPEKVKQYDAKRH", "length": 484 }, "evidence": [ { "id": "HGNC:16976", "url": "https://alliancegenome.org/gene/HGNC:16976#orthology", "database": "AGR" }, { "id": "MGI:2384749", "url": "https://alliancegenome.org/gene/MGI:2384749#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A8DZD4", "url": "https://www.uniprot.org/uniprotkb/A8DZD4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "A8DZD4", "url": "https://www.uniprot.org/uniprotkb/A8DZD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A8DZD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DZD4" }, { "id": "PS50191", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50191" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CRAL-TRIO", "eco_id": "ECO_0000259", "start_pos": 203, "end_pos": 360, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 234, "end_pos": 236 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A3KPN8-1", "uniprot_ac": "A3KPN8", "uniprot_id": "TTC38_DANRE", "mass": { "chemical_mass": 52792.0, "monoisotopic_mass": 52792.0 }, "refseq": { "ac": "NP_001018535", "name": "tetratricopeptide repeat protein 38", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018535" }, "gene_names": [ { "name": "ttc38", "type": "recommended", "evidence": [ { "id": "A3KPN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPN8" } ] }, { "name": "fb96d09", "type": "synonym", "evidence": [ { "id": "NP_001018535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018535" }, { "id": "A3KPN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPN8" } ] }, { "name": "si:ch211-249g22.2", "type": "synonym", "evidence": [ { "id": "NP_001018535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018535" }, { "id": "A3KPN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPN8" } ] }, { "name": "ttc38", "type": "synonym", "evidence": [ { "id": "NP_001018535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018535" } ] }, { "name": "wu:fb96d09", "type": "synonym", "evidence": [ { "id": "NP_001018535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018535" }, { "id": "A3KPN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPN8" } ] }, { "name": "zgc:112407", "type": "synonym", "evidence": [ { "id": "NP_001018535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018535" }, { "id": "A3KPN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPN8" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 38", "type": "recommended", "evidence": [ { "id": "A3KPN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPN8/entry#names_and_taxonomy" } ] }, { "name": "TPR repeat protein 38", "type": "synonym", "evidence": [ { "id": "NP_001018535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018535" }, { "id": "A3KPN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPN8/entry#names_and_taxonomy" } ] }, { "name": "UPF0530 protein", "type": "synonym", "evidence": [ { "id": "NP_001018535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018535" } ] }, { "name": "tetratricopeptide repeat protein 38", "type": "synonym", "evidence": [ { "id": "NP_001018535", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018535" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588715.358594.1, SRR32588723.3471016.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On or before Jul 28, 2025 this sequence version replaced XP_005159083.1, NP_001018535.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001018535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018535" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KPN8", "url": "https://www.uniprot.org/uniprotkb/A3KPN8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ttc38", "url": "https://www.uniprot.org/uniprotkb/A3KPN8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050522-318", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-318", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A3KPN8", "url": "https://alphafold.ebi.ac.uk/entry/A3KPN8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd05804", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05804", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "553728", "url": "https://www.ncbi.nlm.nih.gov/gene/553728", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:553728", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553728", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M2B5G9", "url": "https://www.orthodb.org/?gene=A0A8M2B5G9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A3KPN8", "url": "https://www.orthodb.org/?gene=A3KPN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16263", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16263", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16263:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16263:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR:A3KPN8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A3KPN8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001018535", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018535", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B5G9", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B5G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B5G9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B5G9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KPN8", "url": "https://www.uniprot.org/uniprotkb/A3KPN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KPN8-1", "url": "https://www.uniprot.org/uniprotkb/A3KPN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050522-318", "url": "https://zfin.org/ZDB-GENE-050522-318", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MICVVIMRHQAWQSDGLPLSSSSNEACKLYDAILSQYVTWRNDETLGGIEGCITSIKAADPDFVMGHVISTGLELVGTGSSVLRDERLASAVRRTVELADTQQLTSREKNHVKAVQLFSKGALHKACEVWECILADHPTDLLALKFAHDGFFYLGEQTQMRDSVARVMPHWKPHMPLYRQIKGMYSFGLLETRLYDEAEKMAKEALSLTPEDGWSVHAVAHVHEMKAEVEKGLNFMASTEKNWTVCDMLACHNYWHWALYHIEKGNYEAALKIFDEQVSQRCVKSGAMLDIVDSCSLLYRLELEGVSVGERYRELLQVTQPHSEDHTLLFNDLHFLMVSLGSKDTGTTQRLLESLQELAKDPAENRQLQIAERVGLPMCQALLEFEQRNYRQAVELLKPIKQSFVEIGGSDAQRDVFSQLLIHAAMKSGDKEHQQLARCMLMERDAVRPNSPLTDRLIQRAHSLHA", "length": 466, "header": "sp|A3KPN8-1|TTC38_DANRE Isoform 1 of Tetratricopeptide repeat protein 38 OS=Danio rerio OX=7955 GN=ttc38 PE=3 SV=1 CANONICAL=A3KPN8-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B5G9-1", "url": "https://www.uniprot.org/uniprotkb/A3KPN8/entry#A0A8M2B5G9-1", "sequence": { "sequence": "MHAASFRDCKAWQSDGLPLSTSSNEACKLYDAILSQYVTWRNDETLGGIEGCITSIKAADPDFVMGHVISTGLELVGTGSSVLRDERLASAVRRTVELADTQQLTSREKNHVKAVQLFSKGALHKACEVWECILADHPTDLLALKFAHDGFFYLGEQTQMRDSVARVMPHWKPHMPLYSYIKGMYSFGLLETRLYDEAEKMAKEALSLTPEDGWSVHAVAHVHEMKAEVDKGLNFMASTEKNWMVCDMLACHNYWHWALYHIEKGNYEAALKIFDEQVSQRCVKSGAMLDIVDSCSLLYRLELEGVSVGERYRELLQVTQPHSEDHTLLFNDLHFLMVSLGSKDTGTTQRLLESLQELAKDPAENRQLQIAERVGLPMCQALLEFEQRNYRQAVELLKPIKQSFVEIGGSDAQRDVFSQLLIHAAMKSGDKEHQQLARCMLMERDAVRPNSPLTDRLIQRAHSLHA", "length": 466, "header": "tr|A0A8M2B5G9-1|TTC38_DANRE Computationally mapped isoform of Tetratricopeptide repeat protein 38 OS=Danio rerio OX=7955 GN=ttc38 PE=3 SV=1 CANONICAL=A3KPN8-1" }, "locus": {} }, { "isoform_ac": "A3KPN8-1", "url": "https://www.uniprot.org/uniprotkb/A3KPN8/entry#A3KPN8-1", "sequence": { "sequence": "MICVVIMRHQAWQSDGLPLSSSSNEACKLYDAILSQYVTWRNDETLGGIEGCITSIKAADPDFVMGHVISTGLELVGTGSSVLRDERLASAVRRTVELADTQQLTSREKNHVKAVQLFSKGALHKACEVWECILADHPTDLLALKFAHDGFFYLGEQTQMRDSVARVMPHWKPHMPLYRQIKGMYSFGLLETRLYDEAEKMAKEALSLTPEDGWSVHAVAHVHEMKAEVEKGLNFMASTEKNWTVCDMLACHNYWHWALYHIEKGNYEAALKIFDEQVSQRCVKSGAMLDIVDSCSLLYRLELEGVSVGERYRELLQVTQPHSEDHTLLFNDLHFLMVSLGSKDTGTTQRLLESLQELAKDPAENRQLQIAERVGLPMCQALLEFEQRNYRQAVELLKPIKQSFVEIGGSDAQRDVFSQLLIHAAMKSGDKEHQQLARCMLMERDAVRPNSPLTDRLIQRAHSLHA", "length": 466, "header": "sp|A3KPN8-1|TTC38_DANRE Isoform 1 of Tetratricopeptide repeat protein 38 OS=Danio rerio OX=7955 GN=ttc38 PE=3 SV=1 CANONICAL=A3KPN8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "A3KPN8", "url": "https://www.uniprot.org/uniprotkb/A3KPN8" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:553728", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553728", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A3KMP2-1", "protein_name": "Tetratricopeptide repeat protein 38", "gene_name": "Ttc38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLRDCQAWKNAGLPLSTTSNEACKLFDATLTQYVKWTNDKSLGGIEGCLSKLRAADPTFAMGLAISNGLVLVGTGTSVALDKDLALAVKTMVELSQTQTLTPREQLHVSAVEMFAKGNFPRACDLWEQILRDHPTDMLALKFSHDAYFYLGYQEQMRDSVARVYPFWTPDIPLNSYVKGIYSFGLMETNFYDQAQKLAKEALSIEPTDAWSVHTVAHVHEMRAEIKDGLEFMQQSEGHWKDSDMLACHNYWHWALYLIEKGDYEAALTIYDSHILPSLQASGTMLDVVDSCSMLYRLQMEGVPLGQRWQTVLPVTQKHTRDHILLFNDAHFLMASLGARDLQTTRELLTTLQEASKSPGENCQHQLAKDVGLPLCQALLEAENGNPDRVLELLLPIRYRIVQIGGSNAQRDVFNQLLIHAAMTCTSSVHKNVARSLLMERDALKPNSPLTERLIRRAAAVHLMQ", "length": 465 }, "evidence": [ { "id": "RGD:1306041", "url": "https://alliancegenome.org/gene/RGD:1306041#orthology", "database": "AGR" }, { "id": "MGI:2146198", "url": "https://alliancegenome.org/gene/MGI:2146198#orthology", "database": "AGR" }, { "id": "HGNC:26082", "url": "https://alliancegenome.org/gene/HGNC:26082#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-318", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-318#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4ACL2-1", "protein_name": "Tetratricopeptide repeat protein 38", "gene_name": "Ttc38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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} ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5R3I4-1", "protein_name": "Tetratricopeptide repeat protein 38", "gene_name": "TTC38", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAASPLRDCQAWKDARLPLSTTSNEACKLFDATLTQYVKWTNDKSLGGIEGCLSKLKAADPTFVMGHAMATGLVLIGTGSSVKLDKELDLAVKTMVEISRTQPLTRREQLHVSAVETFANGNFPKACELWEQILQDHPTDMLALKFSHDAYFYLGYQEQMRDSVARIYPFWTPDIPLSSYVKGIYSFGLMETNFYDQAEKLAKEALSINPTDAWSVHTVAHIHEMKAEIKDGLEFMQHSETFWKDSDMLACHNYWHWALYLIEKGEYEAALTIYDTHILPSLQANDAMLDVVDSCSMLYRLQMEGVSVGQRWQDVLPVARKHSRDHILLFNDAHFLMASLGAHDPQTTQELLTTLRDASESPGENCQHLLARDVGLPLCQALVEAEDGNPDRVLELLLPIRYRIVQLGGSNAQRDVFNQLLIHAALNCTSSVHKNVARSLLMERDALKPNSPLTERLIRKAATVHLMQ", "length": 469 }, "evidence": [ { "id": "RGD:1306041", "url": "https://alliancegenome.org/gene/RGD:1306041#orthology", "database": "AGR" }, { "id": "MGI:2146198", "url": "https://alliancegenome.org/gene/MGI:2146198#orthology", "database": "AGR" }, { "id": "HGNC:26082", "url": "https://alliancegenome.org/gene/HGNC:26082#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-318", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-318#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 242, "end_pos": 244 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5WW64-1", "uniprot_ac": "A5WW64", "uniprot_id": "A5WW64_DANRE", "mass": { "chemical_mass": 16951.0, "monoisotopic_mass": 16951.0 }, "refseq": { "ac": "NP_001093529", "name": "uncharacterized protein LOC797776 isoform 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093529" }, "gene_names": [ { "name": "si:ch211-133n4.6", "type": "recommended", "evidence": [ { "id": "A5WW64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WW64" } ] }, { "name": "si:ch211-133n4.6", "type": "synonym", "evidence": [ { "id": "NP_001093529", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093529" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC797776 precursor", "type": "synonym", "evidence": [ { "id": "A5WW64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WW64/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC797776 isoform 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001093529", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093529" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588721.1524439.1, SRR32588730.14295877.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505377 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Jul 26, 2007 this sequence version replaced XP_001333721.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001093529", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093529" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WW64", "url": "https://www.uniprot.org/uniprotkb/A5WW64" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-133n4.6", "url": "https://www.uniprot.org/uniprotkb/A5WW64", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-571", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-571", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092099", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092099", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "797776", "url": "https://www.ncbi.nlm.nih.gov/gene/797776", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:797776", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797776", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M2B5Y8", "url": "https://www.orthodb.org/?gene=A0A8M2B5Y8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A5WW64", "url": "https://www.orthodb.org/?gene=A5WW64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001093529", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093529", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B5Y8", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B5Y8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B5Y8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B5Y8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HZC2", "url": "https://www.uniprot.org/uniprotkb/A0AC58HZC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HZC2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HZC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HZD7", "url": "https://www.uniprot.org/uniprotkb/A0AC58HZD7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HZD7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HZD7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WW64", "url": "https://www.uniprot.org/uniprotkb/A5WW64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WW64-1", "url": "https://www.uniprot.org/uniprotkb/A5WW64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-571", "url": "https://zfin.org/ZDB-GENE-060503-571", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLTRNILILCSLALILVKADLEAAEGGSQAMFATDQDSTSDEAPTESMNLVSPDLPNDELLYYNGATADASSTSSEAGNSAPQVNDVPKADAAKSSMEENDEDEAPDSEEVAAVKPAPVPVPVQRATKSHNAPSTSSTSSSSSRKRSKPASGSKKRSRNQRP", "length": 162, "header": "tr|A5WW64-1|A5WW64_DANRE Isoform 1 of Uncharacterized protein LOC797776 precursor OS=Danio rerio OX=7955 GN=si:ch211-133n4.6 PE=4 SV=1 CANONICAL=A5WW64-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B5Y8-1", "url": "https://www.uniprot.org/uniprotkb/A5WW64/entry#A0A8M2B5Y8-1", "sequence": { "sequence": "MLTRNILILCSLALILVKADLEAAEGGSQAMFATDQDSTSDEAPTESMNLVSPDLPNDELLYYNGATADASSTSSEAGNSAPQVNDVPKADAAKSSMEENDDEAPDSEEVAAVKPAPVPVPVQRATKSHNAPSTSSTSSSSSRKRSKPASGSKKRSRNQRP", "length": 161, "header": "tr|A0A8M2B5Y8-1|A5WW64_DANRE Computationally mapped isoform of Uncharacterized protein LOC797776 precursor OS=Danio rerio OX=7955 GN=si:ch211-133n4.6 PE=4 SV=1 CANONICAL=A5WW64-1" }, "locus": {} }, { "isoform_ac": "A0AC58HZC2-1", "url": "https://www.uniprot.org/uniprotkb/A5WW64/entry#A0AC58HZC2-1", "sequence": { "sequence": "MFATDQDSTSDEAPTESMNLVSPDLPNDELLYYNGATADASSTSSEAGNSAPQVNDVPKADAAKSSMEENDEDEAPDSEEVAAVKPAPVPVPVQRATKSHNAPSTSSTSSSSSRKRSKPASGSKKRSRNQRP", "length": 132, "header": "tr|A0AC58HZC2-1|A0AC58HZC2_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=si:ch211-133n4.6 PE=4 SV=1 CANONICAL=A5WW64-1" }, "locus": {} }, { "isoform_ac": "A0AC58HZD7-1", "url": "https://www.uniprot.org/uniprotkb/A5WW64/entry#A0AC58HZD7-1", "sequence": { "sequence": "MFATDQDSTSDEAPTESMNLVSPDLPNDELLYYNGATADASSTSSEAGNSAPQVNDVPKADAAKSSMEENDDEAPDSEEVAAVKPAPVPVPVQRATKSHNAPSTSSTSSSSSRKRSKPASGSKKRSRNQRP", "length": 131, "header": "tr|A0AC58HZD7-1|A0AC58HZD7_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=si:ch211-133n4.6 PE=4 SV=1 CANONICAL=A5WW64-1" }, "locus": {} }, { "isoform_ac": "A5WW64-1", "url": "https://www.uniprot.org/uniprotkb/A5WW64/entry#A5WW64-1", "sequence": { "sequence": "MLTRNILILCSLALILVKADLEAAEGGSQAMFATDQDSTSDEAPTESMNLVSPDLPNDELLYYNGATADASSTSSEAGNSAPQVNDVPKADAAKSSMEENDEDEAPDSEEVAAVKPAPVPVPVQRATKSHNAPSTSSTSSSSSRKRSKPASGSKKRSRNQRP", "length": 162, "header": "tr|A5WW64-1|A5WW64_DANRE Isoform 1 of Uncharacterized protein LOC797776 precursor OS=Danio rerio OX=7955 GN=si:ch211-133n4.6 PE=4 SV=1 CANONICAL=A5WW64-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A5WW64", "url": "https://www.uniprot.org/uniprotkb/A5WW64" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:797776", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797776", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PL00-1", "uniprot_ac": "A0A8M9PL00", "uniprot_id": "A0A8M9PL00_DANRE", "mass": { "chemical_mass": 177725.0, "monoisotopic_mass": 177725.0 }, "refseq": { "ac": "XP_021325579", "name": "tensin-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325579" }, "gene_names": [ { "name": "tns2a", "type": "recommended", "evidence": [ { "id": "A0A8M9PL00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00" } ] }, { "name": "tns2a", "type": "synonym", "evidence": [ { "id": "XP_021325579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325579" } ] } ], "protein_names": [ { "name": "Tensin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PL00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#names_and_taxonomy" } ] }, { "name": "tensin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325579", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325579" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325579.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325579", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325579" } ] } ], "disease": [ { "disease_id": "DOID:0060852", "recommended_name": { "id": "DOID:0060852", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060852", "name": "Pierson syndrome", "description": "A syndrome characterized by nephrotic syndrome with diffuse mesangial sclerosis, proteinuria, microcoria, absence of the pupillary dilator muscle in the iris, ciliary muscle atrophy, and abnormal eye development with lens-shape, retinal and corneal anomalies that has_material_basis_in homozygous or compound heterozygous mutation in the LAMB2 gene on chromosome 3p21." }, "synonyms": [ { "id": "DOID:0060852", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060852", "name": "microcoria-congenital nephrosis syndrome", "description": "" }, { "id": "MONDO:0012184", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012184", "name": "Pierson syndrome", "description": "Pierson syndrome is characterized by the association of congenital nephrotic syndrome and ocular anomalies with microcoria." }, { "id": "MONDO:0012184", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012184", "name": "Pierson syndrome", "description": "" }, { "id": "MONDO:0012184", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012184", "name": "microcoria-congenital nephrosis syndrome", "description": "" }, { "id": "MONDO:0012184", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012184", "name": "microcoria - congenital nephrosis", "description": "" }, { "id": "MONDO:0012184", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012184", "name": "microcoria - congenital nephrotic syndrome", "description": "" }, { "id": "MIM:609049", "resource": "MIM", "url": 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}, { "id": "A0AC58IP09", "url": "https://www.uniprot.org/uniprotkb/A0AC58IP09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IP09-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IP09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090312-163", "url": "https://zfin.org/ZDB-GENE-090312-163", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGCALSGDSCGDEPDPVPVRGSLRRERAKSRGNMRLTKAGKGEPHVFKEKAFKKKRQCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGTSSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPGMSSVIGLCQHHSTHPHQSLPPPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRWTNSDSTTSKVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1616, "header": "tr|A0A8M9PL00-1|A0A8M9PL00_DANRE Isoform 1 of Tensin-2 isoform X1 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=2 CANONICAL=A0A8M9PL00-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B8V3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0A8M2B8V3-1", "sequence": { "sequence": "MTSFRKTFLAGIFSNNMNKAGKGEPHVFKEKAFKKKRQCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGTSSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPGMSSVIGLCQHHSTHPHQSLPPPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRWTNSDSTTSKVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1597, "header": "tr|A0A8M2B8V3-1|A0A8M9PL00_DANRE Computationally mapped isoform of Tensin-2 isoform X1 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=1 CANONICAL=A0A8M9PL00-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P5D1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0A8M9P5D1-1", "sequence": { "sequence": "MGCALSGDSCGDEPDPVPVRGSLRRERAKSRGNMRLTKAGKGEPHVFKEKAFKKKRQCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGTSSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRWTNSDSTTSKVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1593, "header": "tr|A0A8M9P5D1-1|A0A8M9PL00_DANRE Computationally mapped isoform of Tensin-2 isoform X1 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=2 CANONICAL=A0A8M9PL00-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PL00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0A8M9PL00-1", "sequence": { "sequence": "MGCALSGDSCGDEPDPVPVRGSLRRERAKSRGNMRLTKAGKGEPHVFKEKAFKKKRQCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGTSSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPGMSSVIGLCQHHSTHPHQSLPPPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRWTNSDSTTSKVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1616, "header": "tr|A0A8M9PL00-1|A0A8M9PL00_DANRE Isoform 1 of Tensin-2 isoform X1 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=2 CANONICAL=A0A8M9PL00-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PWP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0A8M9PWP4-1", "sequence": { "sequence": "MSCCSWKERQRPEFHRTVQAGKGEPHVFKEKAFKKKRQCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGTSSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPGMSSVIGLCQHHSTHPHQSLPPPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRWTNSDSTTSKVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1597, "header": "tr|A0A8M9PWP4-1|A0A8M9PL00_DANRE Computationally mapped isoform of Tensin-2 isoform X1 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=1 CANONICAL=A0A8M9PL00-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PWR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0A8M9PWR1-1", "sequence": { "sequence": "MGCALSGDSCGDEPDPVPVRGSLRRERAKSRGNMRLTKAGKGEPHVFKEKAFKKKRQCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGTSSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPGMSSVIGLCQHHSTHPHQSLPPPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1606, "header": "tr|A0A8M9PWR1-1|A0A8M9PL00_DANRE Computationally mapped isoform of Tensin-2 isoform X1 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=2 CANONICAL=A0A8M9PL00-1" }, "locus": {} }, { "isoform_ac": "A0AC58INX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0AC58INX2-1", "sequence": { "sequence": "MSCCSWKERQRPEFHRTVQAGKGEPHVFKEKAFKKKRQCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGTSSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPGMSSVIGLCQHHSTHPHQSLPPPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1587, "header": "tr|A0AC58INX2-1|A0AC58INX2_DANRE Computationally mapped isoform of Tensin-2 isoform X6 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=1 CANONICAL=A0A8M9PL00-1" }, "locus": {} }, { "isoform_ac": "A0AC58INX7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0AC58INX7-1", "sequence": { "sequence": "MSCCSWKERQRPEFHRTVQAGKGEPHVFKEKAFKKKRQCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGTSSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRWTNSDSTTSKVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1574, "header": "tr|A0AC58INX7-1|A0AC58INX7_DANRE Computationally mapped isoform of Tensin-2 isoform X8 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=1 CANONICAL=A0A8M9PL00-1" }, "locus": {} }, { "isoform_ac": "A0AC58INZ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0AC58INZ3-1", "sequence": { "sequence": "MTSFRKTFLAGIFSNNMNKAGKGEPHVFKEKAFKKKRQCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGTSSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRWTNSDSTTSKVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1574, "header": "tr|A0AC58INZ3-1|A0AC58INZ3_DANRE Computationally mapped isoform of Tensin-2 isoform X10 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=1 CANONICAL=A0A8M9PL00-1" }, "locus": {} }, { "isoform_ac": "A0AC58INZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0AC58INZ4-1", "sequence": { "sequence": "MTSFRKTFLAGIFSNNMNKAGKGEPHVFKEKAFKKKRQCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGTSSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPGMSSVIGLCQHHSTHPHQSLPPPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1587, "header": "tr|A0AC58INZ4-1|A0AC58INZ4_DANRE Computationally mapped isoform of Tensin-2 isoform X9 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=1 CANONICAL=A0A8M9PL00-1" }, "locus": {} }, { "isoform_ac": "A0AC58INZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0AC58INZ9-1", "sequence": { "sequence": "MGCALSGDSCGDEPDPVPVRGSLRRERAKSRGNMRLTKAGKGEPHVFKEKAFKKKRQCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGTSSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1583, "header": "tr|A0AC58INZ9-1|A0AC58INZ9_DANRE Computationally mapped isoform of Tensin-2 isoform X7 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=1 CANONICAL=A0A8M9PL00-1" }, "locus": {} }, { "isoform_ac": "A0AC58IP00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0AC58IP00-1", "sequence": { "sequence": "MDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1447, "header": "tr|A0AC58IP00-1|A0AC58IP00_DANRE Computationally mapped isoform of Tensin-2 isoform X13 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=1 CANONICAL=A0A8M9PL00-1" }, "locus": {} }, { "isoform_ac": "A0AC58IP07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0AC58IP07-1", "sequence": { "sequence": "MDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPGMSSVIGLCQHHSTHPHQSLPPPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRWTNSDSTTSKVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1480, "header": "tr|A0AC58IP07-1|A0AC58IP07_DANRE Computationally mapped isoform of Tensin-2 isoform X11 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=1 CANONICAL=A0A8M9PL00-1" }, "locus": {} }, { "isoform_ac": "A0AC58IP09-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00/entry#A0AC58IP09-1", "sequence": { "sequence": "MDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPGMSSVIGLCQHHSTHPHQSLPPPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1470, "header": "tr|A0AC58IP09-1|A0AC58IP09_DANRE Computationally mapped isoform of Tensin-2 isoform X12 OS=Danio rerio OX=7955 GN=tns2a PE=3 SV=1 CANONICAL=A0A8M9PL00-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:799109", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799109", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A502-1", "protein_name": "Tensin 3", "gene_name": "Tns3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRPGDPQGSGARAVRGDCPSRLEGALPRARAASQEDGPAREQLGAQLRFGHRPAGLRCGFAQPEEFTTCPHSFKKKDFKKHRVCGVCRQTIDGQGIACRTCKYSCHKKCEAQVVTTCSAQVHLDQAPEGSTPSAPLRCDKPSRPVVLSSAMEDSHELDLTYVTERIIAVSFPASCSEESYLHSLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMEPSQKRYVQFLSGLLSGAVKMNASPLFLHFVILHGAPSFDTGGACRPFLKLYQAMQPVYTSGIYNVGSENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGSEHLYSDQGVTVDYNTADPLIRWDSYENMSADGEVLHTQGPVDGSLYAKVRKKSASDSGIPSSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERQTPGARRGLSPQEKAELDQLLSGFGLEDSANSHKDMTDMRSKYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSTHLGPFACLKSSQNSLLSDGFGNGVAEDHNGVLSPDLGLGVDSVYERERMCGGREQKQLQPLSRKPSAPTPTQAYGQSNYSTQTWVRQQQMVTAHQYSFASDGEARHGSRSAVDSAGLAQPSPHIPVTPTHGTSSRVAVQRGISNGPNPPDAQQLCPSKALQPRFPDDRVMNGVVHQELNPGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHLSALGLSANGSMYPDGVGSGLRCGGRLDPVDGPGRSPGRQGDDPVGGRLRKLSIGQYDNDAGSQVTFSKCGWGKAGADSAPSLGSFSSPADIKETVITAYPPDLDVIDGRIPNSKESPICLTPAFPVSPETPYVKTSPRYPPFSPPEPQLSIPASLHKGREPRGCTEIISHTVGMSESPLGSKPTLLRADMPATPNFQQVFAASCTVSSNGPGQRRESPPSAERQWAESSPKSTLTLLGNNRPSESPLGTHEFCSSGKNSPGLPCFQSSELQASFHSHELSMSESQDAMPPAGSQTFLGFNTVTTVTSGLPPSEDAGTLLVNSHGPSPVPGTPLTTTGAADNGFLSHNFLTVSPGASSHHSPGLQNQGISLPGQPPLPEKKRTSEGDRSLGSVSPSSSGFSSPHSGSTMSIPFPNVLPDFCKPSEVATPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAVQKALNMTLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVSSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI", "length": 1595 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A656-1", "protein_name": "Tensin-1", "gene_name": "Tns1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCTVSLVCCEALEPLPSCGPQPPGTPPGPARPERSEPGGAASIQRRRLLLQPEDLEAPKTHHFKVKAFKKVKPCGVCRQAITREGCICKVCSFSCHRKCQAKVAAPCVPPSSHELVPIATESVPKNVVDVGEGDCRGGSTPKNLEEAGSMRVSPSIQPQPQPQPQPISLSRNLSVSRAMEDSCELDLVYITERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSEQRPDITKLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQASICITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDEAFKDDRFPDYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFNGHREDGMEEVVGHTQGPLDGSLYAKVKKKDSLNGSSGPITTARPALSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVSGAAIAPAALSPQEKKELDRLLSGFGVDREKQGAMYRAQQLRSHPGGGPTVSSPGRHIVPAQVHVNGGALASERETDILDDELPIQDGQSGGSMGTLSSLDGVTNTSEGGYPETLSPLTNGLDKPYPTEPILNGGGYPYESANRVVPVHSSHSAPIRPSYSAQEGLGGYQREGPHPAWSKQVTSAHRGYDPSGLFRSQSFPDVEPQLPQAPARGGSSREAVQRGLNSWQQQQQQQQQQQQQQQQQQQQQPHPPPRQQERSPLQSLACSKPSPHLSAETPIPALPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLLGSSCQSHPLTQSRSGYIPSGDTLGAPELLSSGRSYSPYDYQLHPAASNQSFRPKSPASSTFLPSPHSSAGPQEPPASLPGLIAEPQLPLKETTSDTSRTPEEEPLNLEGLVAHRVAVYNARLQSLRQSSSSRPSLHRLRSASLSRVQARERQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSVARSPPGLAKTPLSALGLKPHNPADILLHPTGEPRSYVESVARTAVAGPRAQDVEPKSFSAPATHAYGHETPLRNGTPGGSFVSPSPLSTSSPILSADSTSVGSFPSAGSSDQGPRTPIQPMLDSSIRSGSLGQPSPAALSYQSSSPVPVGGSSYSSPDYSLQPFSSSPESQGQPHFSAASVHMVPGSPQARHRTVGTNTPPSPGFGRRAINPTMAAPGSPSLSHRQVMGPSGPGFHGNVVSGHPTSATVAPGSPSLGRHPVGSHQVPGLHSGVVTTPGSPSLGRHPGAHQGNLVSSLHGNAVISPGSPSLGRHLGGSGSVVPGSPSLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSSPVANGMASPSGSSTVSFSHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTITQQGKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSVIPLALPCKLVIPSRDPTDESKDSSGPANSTTDLLKQGAACNVLFINSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLSAGQKR", "length": 1916 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AQ81-1", "protein_name": "Tensin 2", "gene_name": "Tns2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLALSSARRSASEVGATPYPILLLLVPRAQCSSSQESPTLSRSTSKNPVHPSVMGMRSQAVEEGVPPSVPRWTSFCIVKPRKAEPHSFREKVFRKKAPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSSCQALPPAELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVHDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGSKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKAAMELQPSQHRYVGYFSGLLSGSIRMNSSPLFLHYVFVPVLPAFEPNTGFQPFLKIYQSMQLVYTSGVYHITGPGPRQICISLEPALLLKGDVMVTCYHKGGQGTDRTLVFRVQFHTCTIHGPRLNFPKDQLDEAWADERFPFQASVEFVFSSSPEKVKGNTPRNDPSVSVDYNMTEPAVRWDSYENFNQHHEDSVDGSLAHTRGPLDGSPYAQVQRVPRQTPPAPSPELPPPPMLSVSSDSGHSSTLTTEHTAESPGRPPPTAAERQELDRLLGGCGVASAGRGAGRETAILDDEEQPSVGGGLHLGMYPGHRPGLSRRCSCRQGLREPCGVPNGGYYRPEGTLERRRPPYGGYEGHPQGYTEASVEKRRLCRSLSEGPYPYAPELGKPANGDFGYRPAGYREVVILEDPGVPALCSCPACEEKMALPTAALYGLRLEREAGEGWSSEVGKPLLHPVRPGHPLPLLVPACGHHHAPVPDYGCLKSPKVGEEGHEGCSYAVCPEGRYGHPGYPALVTYGYGGAVPSYCPAYGRAPHSCGSPSEGRGYPSPGAHSPQAGSVSPGSPPYLQSRKLGYEAPAEDGRDKYSLPGPLASAGPLASTESPEPSWRDGSSGHSTLPRSPRDAQCSASSELSGPSTPLHTSSPVQGKESTRRQDTTRSPSLAPTQRLSPGEALPSVVQGVTEKTPELLASSRPEPLDPSPFSQTSTPSSPNGWPQERSPGGHTNSASPRSPVPTTLPGLRHAPWQGPQGPSDSPDGSPLTPVPTQMPWLVGSPEPPQSSPTPAFPLATSYETNGPTQPPLPEKRHLPGSGQQSSPPARGTNQHVTFASPLPDVTQPPEHPLQENQSSVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPSEQLVRHFLIETGPKGVKIKGCPTEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETSEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPVPVPAIVHFKVSAQGITLTDNQRKVFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPASAIVTFITKVLLGQRK", "length": 1454 }, "evidence": [ { "id": "HGNC:19737", "url": "https://alliancegenome.org/gene/HGNC:19737#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-163#orthology", "database": "AGR" }, { "id": "MGI:2387586", "url": "https://alliancegenome.org/gene/MGI:2387586#orthology", "database": "AGR" }, { "id": "RGD:1310917", "url": "https://alliancegenome.org/gene/RGD:1310917#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PKG9-1", "protein_name": "Tensin-2 isoform X1", "gene_name": "tns2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCIFSKQQWEKETSSQPSDPPKTRDHAEDAEILSLTELEKMGSHCFKERNFKKKLHCAVCRQTLDSLGMYCRECKTAVHKKCEEKVSVPCEAVSDPPPLQNQMNVPQSKASMETVMENLMGSHYDFDLTYITERIISVLYQSDLDEQSYSANLKVVAPMLKSKHQDKFLLINLSEKRHDICRLNPKVEEFGWPDLHAPPLDKICAVCKTMENWLNSDPNNVVVLHCKGNKGKTGVIVAAYMHYSKISAGADQALSTVAMRKFCEDKISSFILPSQNRYIYYFAGLLSGSIKMNSSPLFLHQIHVPVSPNYQSGGGYAPFLKIYQSLQLVYSSGKYDIQGPNSKTLCVNIEPALLLKGDILVKCYHRLSDVCKRECVFRVQFHTCSVHGSQLAFGKGELDHACTDDRFPSDATVELLFSTGPQRRGGDVPGNEPGVSADYGSTDPVVRWDSYENFNLHHEDSVEDISHTRGPLDGSLYAQVKKRRAQGSSPSRCPTSIKPSTYSPTHSSSTSPIHLSVQPLSLSKDTSRSSAAPESLTPLPREKREKDENRERHRETAILDDGECSPLRPDRPVQSCYGHPFSHTHSYCGPDLTSPHAIAVQPKHRTLPCNRTTPLSVRDLCVSQPDLLWERGRCLHHPCPESVRHLYSYPPQETHTHSPIPQTSHSHTLPPQTRAYFSGEACPLFHCSALPQGHNHIPPSLSPNQSLLTSPYRELRYSTTSPTSCSCRDCLRLREDVALHSLRGRELETLPWSREAEFGIRREAPVHWRDGRAESHWEGVQEAEYWRRKIAMSPVMLSYGHCQAVPKQEQAVYVTDPQPEHGLSPFPSPQSSGYHSPHPPCPCSPQPFRDSPGYASISHSQNSSPIALTPSPKRANHNRASAEENQHGPNEEYTKILSDDKSPATFSPPTQNSGPVKAGEMVQIKSPEDVNLPVSLITNISSASGAEDKTTITDCTSNSLLISSQPSSKNMESVQVQTLNPRPLSVPESEQDKGERPGSCYTSTTTSTSPQPPLCSSERSSASEFSSFNLNGERQSVTPLTDCNEESNSDPDGFITPSFPIASHGYPLLTVPHVPYTGYTEITIPTNLAQPPLPEKQRSSPLHNTSDYTPTSLIKSAGKPSVSSAQVHVSFSTTTNEVPPKSTCRIPLSSGVDEPESRLSSKFVQDSSKYWYKPGISRDQAIAVLKDKEAGCFLIRDSNSFQGAYGLALKVSTAPAHTNSHTEPGSAQEQLVRHFLIESGAKGVKIKGCQNETYFGSLSALVYQHSITPVSLPCVLRIPDRDLVGELQDLQSGTNTSTAADLLKQGAACNVLYLNSVETESLTGPQAVSKTTKCTLTQEPRPSPTVVHFKVSTQGITLTDNQRRLFFRRHYPIHSVTFSSVDPLDQRWVDADNTSCKMFGFVARRSGALGNVCHLFAELDPEQPATAIVNFINKVMLGPQQLRK", "length": 1445 }, "evidence": [ { "id": "HGNC:19737", "url": "https://alliancegenome.org/gene/HGNC:19737#orthology", "database": "AGR" }, { "id": "MGI:2387586", "url": "https://alliancegenome.org/gene/MGI:2387586#orthology", "database": "AGR" }, { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" }, { "id": "RGD:1310917", "url": "https://alliancegenome.org/gene/RGD:1310917#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PT37-1", "protein_name": "Tensin-1 isoform X1", "gene_name": "tns1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCTVSFICCEDDFLQMPLDQHVEKKKEEKRLLFKPEEFEAVHSHTFRLKTFKKGKHCGVCKQTVNNEGLICRVCRLACHRKCEVKVSSSCVPVANYELAPSNELPLKHIETTGSTKSSKSMESRRRPSRSLSLIQAMEENYEVDLVYITERIISVTFPSNAEEPSYSANIKEVANMLRSKHGDNYLLFNLSEKRLDISKLNPKVLDFGWPDHHAPALDKICSICKAMDTWMNAGSHNVVVIHNKGNRGRTGVVVAAYMHYSNISASADQALDRFAMKRFYEDKVLPVGQPSQRRYVQYFSGLLSGHIKINNKPLFLHHVIMHGIPNFESKGGCRPFLKIYQAMQPVYTSGIYNVQGDSQTSICITIEPGLLLKGDILLKCYHKRFRSPCRDVIFRVQFHTCAVHDLGIVFGKDELDETFKDDRFPEYGKVEFVFSFGPEKIQGMDHLENGPSVSVDYNTQDALIRWDSYENFNQRCEDSMEDVIHTEGPLDGSLYAKVRKKESLEGGVTANGLPAAADHTLPAVDHTLPPVDHALSVSSDSGNSTASIKTDRTDEASHQPALVSQPSSQPLSPEEKQELDQLLSGLEAPMHRTGYQSSPGGGGGGGGGGVLHLVPAQVHVNGHSNIDRETDILDDDLPISQEGNSVDSLGTLSSFEGRATPADLYYQSETVINGQDMPYLEKIVHEKMLEPRVHSSSSVQEHLGGPSGYANQNGNIYRSQSLGATPNTDQKYMPKAPARTTSSRDAVQRLNVWQQYGVPEVPVTDGVTFNPVLQSHSLPEFPQMASQQEIEQSIEALNMLMLDLDPALTQVPKSHSAPSGESGVVTTQPSFSQTQARPSYQADTAIHDRGAASSMGFPLTFQQVTGEPSQPTMKQQKPTTTSQHVEFASEAGGQAPMSQSTVPSSTFGVLQLKPLNIYPSSTTSQSPEPQETQRSYSSSSSPLPKESEPEDSSYKLEGLVAHRVAEYTARIRCINDSQSAPEFGHRRRSLSFSGLPSGEMSPDEAAVPGRCRTRSEGLSQDESPTRGSSVRSPIRCISPELANTIALNPGGRPKERHMHSYREAFEEMDGGPVSPPPIVGGEVLPQTPAFPVSPQTPYFNMCRSPPGLAKTPLSFLGLKPHNPAEILLNQTGSESEDEEEPRSYVESVAKAAAVPASPTYDSDSLARPAGPSHAYNAPLSSSSPIQNPDPVESTLADSGVGMNSLSQAAVDIFHFQPSEIPYQPPPPPYPTSMLGSYISPSPAEAMQNNTTTIQPLSGSPGTRHHTILSDMASVPNFQHRLANQDGPILGRQQAPANGHVPGIAGSPVQGRHTMVSQGTQSSPILSRQYPVTQGIQSSPILSRQPMGQAVQSSPVLNRQASLNQANQSSPVLSRQQSITLPNQGSPVLSRQSSLSHPSQGSPVLGRHPSLTQGSPSLDRHPMYSGYTTPEERHGALSRQSSSSGYQPPSTPSFPVSPAGYIEGAGFRQGSPAFQPQLPEKRRMSSSDRTNGGLSYGTLNGKMSSPVSSGGSTPSVHFFHTLPDFSKLNMCDGSPETRMNVKFVQDTSKFWYKPDISRDQAINMLKDQDPGAFVIRDSHSFRGAYGLAMKVASPPPTTQPTKKAGDVTNELVRHFLIETSPKGVRLKGCPNEPYFGCLSALVYQHSITPLALPCKLVIPTRDPLEESPEIATPTNPAADMLKQGAGQKSSADGHACNVLYINSVDMESLTGPQAIAKAISETMNASPAPSATIVHFKVSAQGITLTDNQRKLFFRRHYPIGTVTFCDIDPQERKWNKPEGGTAKFFGFVARKQGSTTDNVSHLFAEMDPDQPATAIVNFVSKVMISSQKR", "length": 1830 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A8N8-1", "protein_name": "Si:ch211-191a24.3", "gene_name": "tns3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEGSEFDLNYITERVIGITFHQTCTEQTYQHNLSRITQLLQSKHADRYMVINLSEHSDDLCRMNHRVVDLGWPESHAPSLHLLCSVCKNMDSWLSAHPDNVLLLHCKGSKDRVGVVISSYIQLSSVSTSEEHALDLYSMKRFCSDQMVNLLTPSQKRYVQVFGRLLKHQIPLNHSPLFIHHVTIHPIPDFHPTVCQLFIRVNQGTQTAYTSGLHQVDVGLMDRVCFVLDPPQMIKGDIMIVCYHKNVSTRTQETLFRAQFHTAALSAKQFALQKEDLDLANKDPRFPENCVVEVLFSEVADKDPTLASDCDQWRSSLAVVIENDLPDSLQTQWDLSENLPATAKPHEGTRSLSSDSGLSSSSQWTGGQASGLLISYSPEENNQLNTVTPGLRMEEEQSSPGTLRRDPTTSQSVLDYSGHLNGDSMFTERETDIIDDDEDDITSPNDAIAAVSDSLSFKETSGLSSGQSSDYQNEASPAKFRGDVNTSNSVIDTSVPAGYQTRIWVKQQQSTSYAHTPTDRLEVKQELRSDASKPSTPDNCLPEAPSETDKDDVMALDQSIEQLNQLILDLDPEFKPIPTQPQSHMTRSASLYTNGKTQSMGKAKSHLSGWRQKQLSDVSEYSVLQNTSGDQTQNTQRFDFSTPSLRGLYHTDAVDFGDLPPEVDRPLWVGLNQAPPTPAFPVTPPTPYVKSGNDFTNSRPGSQTSRHYMSSPVWQESRGFTDSMTHTSMSSDGEIFHSDVTGSPASCQRMFGSLHSISTPSPLVNADSPTPAHSWLEGGSSTPLSHYTPQPSPPLTLSAPNSHSSPRRAPRSLSSALDMGSLESSLLEAVEGLEALGLDVAQPPLLPLKRRGTDGSENMLSFPLSRSTVSTSYASHNTSPSRSTPSPDFMASKPENVKFVQDTSKFWYKPDISREQAISVLKDKEPGSFIIRDSHSFRGAYGLAMKVATPPPTVLQTSRKVGDLSNELVRHFLIECTPKGVRLKGCPNEPYFGSLTALVCQHSITPLALPCRLIIPSRDPLEEFNESPTQTSTNSAAELLKQGAACNVWFLGSVDLESLTGVQGVQKATTVTFNKDPPPTSTVVHFKVSAQGITLTDNQRKLFFRRHYAVSTVIFCALDPQDRKWKRDGCTAAKIFGFIARKSGSSTENVCHLFAEHDPEQPASAIVNFVSKVMIGSQKNK", "length": 1182 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q0S6-1", "protein_name": "Tensin-1", "gene_name": "Tns1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCTVSLVCCEALEPLPSCGPQPPGTPPGPARPERCEPGGAAPDPRRRLLLQPEDLEAPKTHHFKVKAFKKVKPCGICRQAITREGCVCKVCSFSCHRKCQAKVAAPCVPPSSHELVPITTETVPKNVVDVGEGDCRVGSSPKNLEEGGSMRVSPSIQPQPQSQPTSLSRNTSVSRAMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSEQRPDITKLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYLHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQASICITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDEAFKDDRFPDYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHREDGMEEVVGHTQGPLDGSLYAKVKKKDSLNGSSGPVTTARPALSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVSGATTAPAALSPQEKKELDRLLSGFGVDREKQGAMYRAQQLRSHPGGGPTVPSPGRHIVPAQVHVNGGALASERETDILDDELPIQDGQSGGSMGTLSSLDGVTNTSESGYPETLSPLTNGLDKPYSTEPVLNGGGYPYEAANRVIPVHSSHSAPIRPSYSAQEGLAGYQREGPHPAWSQQVTSAHCGCDPSGLFRSQSFPDVEPQLPQAPTRGGSSREAVQRGLNSWQQQQPHPPPRQQERSPLQSLARSKPSPQLSAETPVAALPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLLGSSRQSHPLTQSRSGYIPSGHSLGTPELVSSGRPYSPYDYQLHPAGSNQSFHPKSPASSTFLPSPHSSAGPQEPPASLPGLIAQPQLPPKETTSDPSRTPEEEPLNLEGLVAHRVAGVQARERQPAEPPGPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPHSVARSPPGLAKTPLSALGLKPHNPADILLHPTGVARRLIQPEEDEGEEVTKPPEEPRSYVESVARTAVAGPRAQDVEPKSFSAPAAHAYGHETPLRNGTPGGSFVSPSPLSTSSPILSADSTSVGSFPSVVSSDQGPRTPFQPMLDSSIRSGSLGQPSPAALSYQSSSPVPVGGSSYNSPDYSLQPFSSSPESQGQPQYSAASVHMVPGSPQARHRTVGTNTPPSPGFGRRAVNPTMAAPGSPSLSHRQVMGPSGPGFHGNVVSGHPASAATTPGSPSLGRHPVGSHQVPGLHSSVVTTPGSPSLGRHPGAHQGNLASSLHSNAVISPGSPSLGRHLGGSGSVVPGSPSLDRHAAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSSPVANGMASGSSTVSFSHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTITQQGKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSVIPLALPCKLVIPSRDPTDESKDSSGPANSTTDLLKQGAACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLSAGQKR", "length": 1888 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4V8I3-1", "protein_name": "Tensin-4", "gene_name": "Tns4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSSLLTGGHVVSLTPHEESRMALHPTPSHDLPALCPYYTTESWGTQPLMDPTLCKGSSNRLQQAQQAEARAQCLLQCPGEQASGASQDLDSCIDFSLEALNKMILELDPTFQLLPSGIAGPQAEPTNSVASRTKKEEPDALDIKYIEVTSTRSRCLDSPQRCSSPCVTPPFGSPRSGGLFLSRDIPRETRSSSNESLIFSGNQGRGSSPHTPSSLSNSIPCRESRASGSPLATPPGWEKGLRAPQWGSRVSTLSASPVSDISYVFGSNQSLPHSSLSSYPPSSRSLGSPASSSSSLHSLDRGSQCVRSSDAQVPSNPIVGMGQPQAVPSTPVAKEQASSCPPSVTNSMADIPIVLINGNPEPQSPPAQQTPRYQDSVQSRATSPSHLCQATKSHSKTLPDVPLTSPSHLCQATKSHSKTLPDVPLTASPESPAKDMQPTMKFVMDTSKYWFKPSITREQAINLLRTEKPGTFVIRDSSSYRGSFGLALKVQETPASAPNRPGEDSTDFIRHFLVESSAKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQKELGGAEPASDSPTHGQTSCLKISAGCHTLYLTSVSVETLSGALAVQKAISVMLERDVLPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLIALRFCGMDPEQRKWQKYCKPSRIFGFVAKSQTEPQENACHLFAEYDAAQPASQVISLVTALLKDTERV", "length": 718 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5SSZ5-1", "protein_name": "Tensin-3", "gene_name": "Tns3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSHELDLTYVTERIIAVSFPASCSEESYLHSLQEVTRMLKCKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNNDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKISALMEPSQKRYVQFLSGLLSGAMKMNTSPLFLHFVIMHGVPSFDTGGACRPFLKLYQAMQPVYTSGIYNVGSENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGSEHLYSDQGVTVDYNTADPLIRWDSYENMSADGEVLHTQGPVDGSLYAKVRKKSASDTGIPSSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERLTPGARRGLSPQEKAELDQLLSGFGLEDSASSHKDMTDMRSKYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSTHLGPFTCLKSSQNSLLSDGFGNGVAEDHNGVLSPDLGLGVDTLYDRERMCGGREQKPLQPLLRKPSAPTPVQAYGQSNYSTQTWVRQQQMVAAHQYSFASDGEARLGSRSTVDNTGLAQPPPHIPVTPNRGASSRVAVQRGISNGPNPPDTQQLCPGKALQPRFQDDRVTNGVHQEPNTGSSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHLNALGISAVCPDGVGSGLRCSGRLDSVDGPGRSPGRQGDDPIGGRLRKLSIGQYDNDAASQVTFSKCGWGKAGVDPAPSLGSFSSPEDIKETVITAYPSDLNMIDGRIPNSKESSMCLTPSFPVSPETPYVKTSPRYPPFSPPEPQLSSPASLHKGREPRGCPEIISHTVGMSESPVGPKPTMLRADMPATPNFQQVFASSCTVSSNGPGQRRESPPSAERQWVESSPKSTLTLLGNSHPSESPLGTHEFCSSGKDSPGLPCFQSSELQASFHSHELSMSEPQGALPPAGSQTFLGFNTVTTATSVLPPGEDAGTLLVNSHGTSPAPGTPLLTTGAADNGFLPHNFLTVSPGASSHHSPGLQNQNVSLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTMSIPFPNVLPDFCKPSEVASPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAVQKALSMTLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVSSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI", "length": 1440 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63HR2-1", "protein_name": "Tensin-2", "gene_name": "TNS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSSGPVERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK", "length": 1409 }, "evidence": [ { "id": "HGNC:19737", "url": "https://alliancegenome.org/gene/HGNC:19737#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-163#orthology", "database": "AGR" }, { "id": "MGI:2387586", "url": "https://alliancegenome.org/gene/MGI:2387586#orthology", "database": "AGR" }, { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" }, { "id": "RGD:1310917", "url": "https://alliancegenome.org/gene/RGD:1310917#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q68CZ2-1", "protein_name": "Tensin-3", "gene_name": "TNS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSATPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENLSADGEVLHTQGPVDGSLYAKVRKKSSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPGTRRGLSAQEKAELDQLLSGFGLEDPGSSLKEMTDARSKYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCHKSSQNSLLSDGFGSNVGEDPQGTLVPDLGLGMDGPYERERTFGSREPKQPQPLLRKPSVSAQMQAYGQSSYSTQTWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDIIDGRILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPLPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAMKVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAIQKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKV", "length": 1445 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BZ33-1", "protein_name": "Tensin-4", "gene_name": "Tns4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSSLLAGGHMVSLTPCEESRMALHPTPSPGLPALCPYYTTESWGTQPLMAPTLRKGSSDRLQQAQQAEARAHCLLQGPGEQASGASQDLESCIDFSLEALNQMILEIDPTFQLLPSGTAGPQAESTNSIMSRNKKEEPEALDIKYIEVTSTRSRYLDGPQRCSSPCATPPFGSPRSGSLFLSRDIPRETRSSSNESLIFSGNQGRGPSPLTPSSLSNAIPCRESRTSGSPLATPPGWEKGLRAPQRGSRVSILSASPVSDVSYVFGSNQSLPHSSLSSYPSSSRSLGSPASSSSSLHSLDRGSQCGRPSDAQAPSNPILGMGQPQAVQSTPVAKEQASSCPASVTNSMADIPIVLINGSPEPQSPPAQRTPGHQDSVQSRVTSPSHLCQAIKSPSKTLPDVPLPASPDGPAKDMQPTMKFVMDTSKYWFKPSITREQAINLLRTEKPGAFVIRDSSSYRGSFGLALKVQETSASAPNRPGEDSSDLIRHFLIESSAKGVHLKGADEEPYFGSLSSFVCQHSIMALALPCKLTIPQKELGGAEPASDSPTHGQTSCLKISAGCHTLYLSSVSVETLSGALAVQKAISVTLERDVLPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLSALRFCGMDPEQRKWQKYCKPSRIFGFVAKSQTEPQENVCHLFAEYDAVQPASQVISLVTALLQDTERM", "length": 696 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CGB6-1", "protein_name": "Tensin-2", "gene_name": "Tns2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSGPVERLLRALGRRDSSRATSRPRKAEPHSFREKVFRKKTPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSSCQALPPAELRRSTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGSKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYVSYFSGLLSGSIRMNSSPLFLHYVFVPVLPAFEPNTGFQPFLKIYQSMQLVYTSGVYRIAGPGPQQLCISLEPALLLKGDVMVTCYHKGGQGTDRTLVFRVQFHTCTIHGSRLTFPKDQLDEAWADERFPFQASVEFVFSSSPEKVKGNTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGALAHTRGPLDGSPYAQVQRVPRQTPPAPSPELPPPPMLSVSSDSGHSSTLTTEHTAESPGRPPPTAAERQELDRLLGGCGVASAGRGAGRETAILDDEEQPSVGGGLHLGMYSGHRPGLSRRCSCRQGFREPCGVPNGSYYRPEGTLERRRPPYGGYEGHPQGYAEASVEKRRLCRSLSEGPYPYAPELGKPANGDFGYRPAGYREVVILEDPGVPALCSCPACEEKLALPTAALYGLRLEREAAEGWSSEVGKPLLHPVRPGHPLPLLVPACGHHHAPMPDYGCLKPPKVGEEGHEGCSYAVCSEGRYGHSGYPALVTYGYGGAVPSYCPAYGRAPHSCGSPSEGRGYPSPGAHSPRAGSVSPGSPPYLQPRKLGYEISAEDGRDKYPLSGHLASTGPLASTESPEPSWRDGSSGHSTLPRSPRDPQCSASSELSGPSTPLHTSSPVQGKESNRRQDTTRSPSLAPTQRLSPGEALPSVVQGVAEKTPELLTSSRPEQLDPSPFSQTSAPGSPNGWPQERSPGGHTNSASPRSPVPTTLPGLRHAPWQGPRGTSDSPDGSPLTPVPTQMPWLVGSPEPPQSSPTPAFPLATSYDANGPIQPPLPEKRHLPGSGQQPSPPARSTNQHVTFASPLPDVTQPPEHPLQENQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPSEQLVRHFLIETGPKGVKIKGCPTEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVAKASSAALSCSPVPVPAIVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGATSKIFGFVAKKPGSPWENVCHLFAELDPDQPASAIVTFITKVLLGQRK", "length": 1400 }, "evidence": [ { "id": "HGNC:19737", "url": "https://alliancegenome.org/gene/HGNC:19737#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-163#orthology", "database": "AGR" }, { "id": "MGI:2387586", "url": "https://alliancegenome.org/gene/MGI:2387586#orthology", "database": "AGR" }, { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" }, { "id": "RGD:1310917", "url": "https://alliancegenome.org/gene/RGD:1310917#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZW8-1", "protein_name": "Tensin-4", "gene_name": "TNS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQVMSSPLLAGGHAVSLAPCDEPRRTLHPAPSPSLPPQCSYYTTEGWGAQALMAPVPCMGPPGRLQQAPQVEAKATCFLPSPGEKALGTPEDLDSYIDFSLESLNQMILELDPTFQLLPPGTGGSQAELAQSTMSMRKKEESEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLRSGGLLLSRDVPRETRSSSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPFTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEEPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASDSTDSPASCQKKSAGCHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLTTLRFCGMDPEQRKWQKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQPASQVIGLVTALLQDAERM", "length": 715 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HBL0-3", "protein_name": "Tensin-1", "gene_name": "TNS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTWICLSCMLWPEDLEAPKTHRFKVKTFKKVKPCGICRQVITQEGCTCKVCSFSCHRKCQAKVAAPCVPPSNHELVPITTENAPKNVVDKGEGASRGGNTRKSLEDNGSTRVTPSVQPHLQPIRNMSVSRTMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSERRPDITKLHAKVLEFGWPDLHTPALEKICSICKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQTSVCITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDDAFKDDRFPEYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHRDDGMEEVVGHTQGPLDGSLYAKVKKKDSLHGSTGAVNATRPTLSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVPGASSATAALSPQEKRELDRLLSGFGLEREKQGAMYHTQHLRSRPAGGSAVPSSGRHVVPAQVHVNGGALASERETDILDDELPNQDGHSAGSMGTLSSLDGVTNTSEGGYPEALSPLTNGLDKSYPMEPMVNGGGYPYESASRAGPAHAGHTAPMRPSYSAQEGLAGYQREGPHPAWPQPVTTSHYAHDPSGMFRSQSFSEAEPQLPPAPVRGGSSREAVQRGLNSWQQQQQQQQQPRPPPRQQERAHLESLVASRPSPQPLAETPIPSLPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLSGSSRQSHPLTQSRSGYIPSGHSLGTPEPAPRASLESVPPGRSYSPYDYQPCLAGPNQDFHSKSPASSSLPAFLPTTHSPPGPQQPPASLPGLTAQPLLSPKEATSDPSRTPEEEPLNLEGLVAHRVAGVQAREKQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSGVRSPPGLAKTPLSALGLKPHNPADILLHPTGEPRSYVESVARTAVAGPRAQDSEPKSFSAPATQAYGHEIPLRNGTLGGSFVSPSPLSTSSPILSADSTSVGSFPSGESSDQGPRTPTQPLLESGFRSGSLGQPSPSAQRNYQSSSPLPTVGSSYSSPDYSLQHFSSSPESQARAQFSVAGVHTVPGSPQARHRTVGTNTPPSPGFGWRAINPSMAAPSSPSLSHHQMMGPPGTGFHGSTVSSPQSSAATTPGSPSLCRHPAGVYQVSGLHNKVATTPGSPSLGRHPGAHQGNLASGLHSNAIASPGSPSLGRHLGGSGSVVPGSPCLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSPVASGMSSPSGGSTVSFSHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTIMQQNKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSIIPLALPCKLVIPNRDPTDESKDSSGPANSTADLLKQGAACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLNAGQKR", "length": 1839 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VHC3-1", "protein_name": "Tensin", "gene_name": "by", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRTPYEESAAAADHKYQYQYTAANNNNNYYKNYNVNGNGQANGNGNLSGIGNGNGIGNGNGYGIPYHARENSLPFSYGIAKTSTPLRKTPTPTRVDSFLDFDFGPTNTNVNSNSSSNNGGTGDMIKPPTRLTSPLLVRKTLGNAVSPTSSTNTNTIANTYHYTSSSATPTPVRDNFEQLLRERREKVYNEYRNLDRESSGERARVAPAPPQRQYYPSDGYGIGLKNDSNGTLYRKSPSSNGKSTKYNYDFEFNLNLDDVRPEPTPYTTRNIHFEDLRLDQDVPDGVVNRRTMERNYHTINSLETTHKRQQLEPLEQLGAVYGQNHMEETLTRTRRDLSASTSTSKSTSPLPAIGVPAIAPASPIYATSTKRVSNPNTNGQQQMTPSPTSRPETPAFPVTPRTPFGASSSSSASLAPTTQLPPESIYQTGPRRGVPPALQPLEVSADSVQFARSSSQFWYKPNLTREDAIALLASAQPGTFLVRDSTTYKDSYGLVVRVSQPPPGSQELVRHFLIEPTKGGVHLKGCDDEPVFTSLSALVFEHSISQLALPCLLRLPDRDIVPPVRATTPAQQHLLAHGAATNVLWLYSCDTESLTGNEAIRKAIRQMYGQQPLPQPTEVHFKVSSQGITLTDNTRKKFFRKHYKADVISHCAIDPENRMWTSEGESDKKTIFAFVARRSHSSTDNQCHVFCDLSVSQPAAAIVSFANRTLPTEKLRNYVL", "length": 720 }, "evidence": [ { "id": "HGNC:19737", "url": "https://alliancegenome.org/gene/HGNC:19737#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-163", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-163#orthology", "database": "AGR" }, { "id": "MGI:2387586", "url": "https://alliancegenome.org/gene/MGI:2387586#orthology", "database": "AGR" }, { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "focal adhesion", "id": "GO:0005925", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005925", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL00", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL00", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00" } ], "pmid": "" }, { "name": "phosphoprotein phosphatase activity", "id": "GO:0004721", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004721", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL00", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1056, "end_pos": 1058, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1123, "end_pos": 1125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1236, "end_pos": 1238, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1393, "end_pos": 1395, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1468, "end_pos": 1470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 518, "end_pos": 520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 735, "end_pos": 737, "annotation": "n_glycosylation_sequon" }, { "start_pos": 955, "end_pos": 957, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PL00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00" }, { "id": "PS51182", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51182" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 tensin-type", "eco_id": "ECO_0000259", "start_pos": 315, "end_pos": 441, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PL00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00" }, { "id": "PS50081", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phorbol-ester/DAG-type", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 91, "start_aa": "Pro", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PL00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00" }, { "id": "PS51181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatase tensin-type", "eco_id": "ECO_0000259", "start_pos": 138, "end_pos": 310, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PL00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL00" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 1344, "end_pos": 1453, "start_aa": "Trp", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1056, "end_pos": 1058 }, { "start_pos": 1123, "end_pos": 1125 }, { "start_pos": 1236, "end_pos": 1238 }, { "start_pos": 1393, "end_pos": 1395 }, { "start_pos": 1468, "end_pos": 1470 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 314, "end_pos": 316 }, { "start_pos": 518, "end_pos": 520 }, { "start_pos": 735, "end_pos": 737 }, { "start_pos": 955, "end_pos": 957 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PJV5-1", "uniprot_ac": "A0A8M9PJV5", "uniprot_id": "A0A8M9PJV5_DANRE", "mass": { "chemical_mass": 75251.0, "monoisotopic_mass": 75251.0 }, "refseq": { "ac": "XP_021331747", "name": "piggyBac transposable element-derived protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331747" }, "gene_names": [ { "name": "LOC110437782", "type": "recommended", "evidence": [ { "id": "A0A8M9PJV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5" } ] }, { "name": "LOC110437782", "type": "synonym", "evidence": [ { "id": "XP_021331747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331747" } ] } ], "protein_names": [ { "name": "PiggyBac transposable element-derived protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PJV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5/entry#names_and_taxonomy" } ] }, { "name": "piggyBac transposable element-derived protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021331747", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331747" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021331747.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021331747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331747" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110437782", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5", "locus": {} } ], "crossref": [ { "id": "A0A8M9PJV5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PJV5", "database": "AlphaFoldDB", "categories": [] }, { "id": "110437782", "url": "https://www.ncbi.nlm.nih.gov/gene/110437782", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110437782", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437782", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PJV5", "url": "https://www.orthodb.org/?gene=A0A8M9PJV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PJW0", "url": "https://www.orthodb.org/?gene=A0A8M9PJW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PXB2", "url": "https://www.orthodb.org/?gene=A0A8M9PXB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46599", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46599", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46599:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46599:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13843", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021331747", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331747", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PJV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PXB2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PXB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PXB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PXB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TTY8", "url": "https://www.uniprot.org/uniprotkb/A0AB32TTY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TTY8-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TTY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TUP4", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TUP4-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TUV1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TUV1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TW92", "url": "https://www.uniprot.org/uniprotkb/A0AB32TW92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TW92-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TW92-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGE5", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGE5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGE6", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGE6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGE6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGE6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGF5", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGF5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGF5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGF5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MPQKEHPCAFFECKAQHKSLHRLPSNERLRRKWLSIIFEDKVPENLPKLLYVCANHFSADSFENAGQFNSGFASKLFLKTGSVPTRRDPTLLRRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRRPSSDLYLPEEDYDSKDAPQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISKVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSAKNKLLSNAPRGTMRWIRQDKLLFVEWKDSKEVQMCSSFHKAYEGDTVQRKVRRDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCITEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKGNGKKPLTRKAFLQALILELTDIDSLDSAAVPLTLSSSG", "length": 661, "header": "tr|A0A8M9PJV5-1|A0A8M9PJV5_DANRE Isoform 1 of PiggyBac transposable element-derived protein 4 isoform X1 OS=Danio rerio OX=7955 GN=LOC110437782 PE=4 SV=2 CANONICAL=A0A8M9PJV5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PJV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5/entry#A0A8M9PJV5-1", "sequence": { "sequence": "MPQKEHPCAFFECKAQHKSLHRLPSNERLRRKWLSIIFEDKVPENLPKLLYVCANHFSADSFENAGQFNSGFASKLFLKTGSVPTRRDPTLLRRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRRPSSDLYLPEEDYDSKDAPQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISKVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSAKNKLLSNAPRGTMRWIRQDKLLFVEWKDSKEVQMCSSFHKAYEGDTVQRKVRRDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCITEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKGNGKKPLTRKAFLQALILELTDIDSLDSAAVPLTLSSSG", "length": 661, "header": "tr|A0A8M9PJV5-1|A0A8M9PJV5_DANRE Isoform 1 of PiggyBac transposable element-derived protein 4 isoform X1 OS=Danio rerio OX=7955 GN=LOC110437782 PE=4 SV=2 CANONICAL=A0A8M9PJV5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PJW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5/entry#A0A8M9PJW0-1", "sequence": { "sequence": "MPSKRCYFHRGRAFSLFGLPRNREQRERWLQFIFNCVPESYKKDLSLCARHFTKNCFQNYSQFTAGFGLKLLLKEGAVPTIKDDCEPQPRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRRPSSDLYLPEEDYDSKDAPQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISKVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSAKNKLLSNAPRGTMRWIRQDKLLFVEWKDSKEVQMCSSFHKAYEGDTVQRKVRRDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCITEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKGNGKKPLTRKAFLQALILELTDIDSLDSAAVPLTLSSSG", "length": 657, "header": "tr|A0A8M9PJW0-1|A0A8M9PJW0_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X5 OS=Danio rerio OX=7955 GN=LOC110437782 PE=4 SV=2 CANONICAL=A0A8M9PJV5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PXB2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5/entry#A0A8M9PXB2-1", "sequence": { "sequence": "MPQKEHPCAFFECKAQHKSLHRLPSNERLRRKWLSIIFEDKVPENLPKLLYVCANHFSADSFENAGQFNSGFASKLFLKTGSVPTRRDPTLLRRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRPSSDLYLPEEDYDSKDAPQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISKVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSAKNKLLSNAPRGTMRWIRQDKLLFVEWKDSKEVQMCSSFHKAYEGDTVQRKVRRDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCITEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKGNGKKPLTRKAFLQALILELTDIDSLDSAAVPLTLSSSG", "length": 660, "header": "tr|A0A8M9PXB2-1|A0A8M9PJV5_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X1 OS=Danio rerio OX=7955 GN=LOC110437782 PE=4 SV=2 CANONICAL=A0A8M9PJV5-1" }, "locus": {} }, { "isoform_ac": "A0AB32TTY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5/entry#A0AB32TTY8-1", "sequence": { "sequence": "MPSKRCYFHRGRAFSLFGLPRNREQRERWLQFIFNCVPESYKKDLSLCARHFTKNCFQNYSQFTAGFGLKLLLKEGAVPTIKDDCEPQPRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRPSSDLYLPEEDYDSKDAPQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISKVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSAKNKLLSNAPRGTMRWIRQDKLLFVEWKDSKEVQMCSSFHKAYEGDTVQRKVRRDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCITEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKGNGKKPLTRKAFLQALILELTDIDSLDSAAVPLTLSSSG", "length": 656, "header": "tr|A0AB32TTY8-1|A0A8M9PJV5_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X1 OS=Danio rerio OX=7955 GN=LOC110437782 PE=4 SV=2 CANONICAL=A0A8M9PJV5-1" }, "locus": {} }, { "isoform_ac": "A0AB32TUP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5/entry#A0AB32TUP4-1", "sequence": { "sequence": "MPSKRCYFHRESYKKDLSLCARHFTKNCFQNYSQFTAGFGLKLLLKEGAVPTIKDDCEPQPRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRRPSSDLYLPEEDYDSKDAPQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISKVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSAKNKLLSNAPRGTMRWIRQDKLLFVEWKDSKEVQMCSSFHKAYEGDTVQRKVRRDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCITEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKGNGKKPLTRKAFLQALILELTDIDSLDSAAVPLTLSSSG", "length": 629, "header": "tr|A0AB32TUP4-1|A0A8M9PJV5_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X1 OS=Danio rerio OX=7955 GN=LOC110437782 PE=4 SV=2 CANONICAL=A0A8M9PJV5-1" }, "locus": {} }, { "isoform_ac": "A0AB32TUV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5/entry#A0AB32TUV1-1", "sequence": { "sequence": "MSRRRCVLRCERKLVQFTLPKEESARKQWLDFIFTRTPKRYSPNLVLCSRHFTDDCFTNLGAINAGFAKRLKVKEGSVPTLFGPACSSESQPRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRRPSSDLYLPEEDYDSKDAPQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISKVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSAKNKLLSNAPRGTMRWIRQDKLLFVEWKDSKEVQMCSSFHKAYEGDTVQRKVRRDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCITEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKGNGKKPLTRKAFLQALILELTDIDSLDSAAVPLTLSSSG", "length": 660, "header": "tr|A0AB32TUV1-1|A0A8M9PJV5_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X1 OS=Danio rerio OX=7955 GN=LOC110437782 PE=4 SV=2 CANONICAL=A0A8M9PJV5-1" }, "locus": {} }, { "isoform_ac": "A0AB32TW92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5/entry#A0AB32TW92-1", "sequence": { "sequence": "MSRRRCVLRCERKLVQFTLPKEESARKQWLDFIFTRTPKRYSPNLVLCSRHFTDDCFTNLGAINAGFAKRLKVKEGSVPTLFGPACSSESQPRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRPSSDLYLPEEDYDSKDAPQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISKVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSAKNKLLSNAPRGTMRWIRQDKLLFVEWKDSKEVQMCSSFHKAYEGDTVQRKVRRDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCITEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKGNGKKPLTRKAFLQALILELTDIDSLDSAAVPLTLSSSG", "length": 659, "header": "tr|A0AB32TW92-1|A0A8M9PJV5_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X1 OS=Danio rerio OX=7955 GN=LOC110437782 PE=4 SV=2 CANONICAL=A0A8M9PJV5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JGE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5/entry#A0AC58JGE5-1", "sequence": { "sequence": "MFIDDMDPILDRRPSSDLYLPEEDYDSKDAPQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISKVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSAKNKLLSNAPRGTMRWIRQDKLLFVEWKDSKEVQMCSSFHKAYEGDTVQRKVRRDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCITEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKGNGKKPLTRKAFLQALILELTDIDSLDSAAVPLTLSSSG", "length": 510, "header": "tr|A0AC58JGE5-1|A0AC58JGE5_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X9 OS=Danio rerio OX=7955 GN=LOC110437782 PE=4 SV=1 CANONICAL=A0A8M9PJV5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JGE6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5/entry#A0AC58JGE6-1", "sequence": { "sequence": "MPSKRCYFHRESYKKDLSLCARHFTKNCFQNYSQFTAGFGLKLLLKEGAVPTIKDDCEPQPRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRPSSDLYLPEEDYDSKDAPQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISKVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSAKNKLLSNAPRGTMRWIRQDKLLFVEWKDSKEVQMCSSFHKAYEGDTVQRKVRRDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCITEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKGNGKKPLTRKAFLQALILELTDIDSLDSAAVPLTLSSSG", "length": 628, "header": "tr|A0AC58JGE6-1|A0AC58JGE6_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X8 OS=Danio rerio OX=7955 GN=LOC110437782 PE=4 SV=1 CANONICAL=A0A8M9PJV5-1" }, "locus": {} }, { "isoform_ac": "A0AC58JGF5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5/entry#A0AC58JGF5-1", "sequence": { "sequence": "MFIDDMDPILDRPSSDLYLPEEDYDSKDAPQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISKVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSAKNKLLSNAPRGTMRWIRQDKLLFVEWKDSKEVQMCSSFHKAYEGDTVQRKVRRDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCITEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKGNGKKPLTRKAFLQALILELTDIDSLDSAAVPLTLSSSG", "length": 509, "header": "tr|A0AC58JGF5-1|A0AC58JGF5_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X10 OS=Danio rerio OX=7955 GN=LOC110437782 PE=4 SV=1 CANONICAL=A0A8M9PJV5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110437782", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437782", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJV5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 383, "end_pos": 385, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PJV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV5" }, { "id": "PS50950", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50950" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "THAP-type", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 87, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 383, "end_pos": 385 }, { "start_pos": 492, "end_pos": 494 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, 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"evidence": [ { "id": "A0A8M9PMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMC5/entry#names_and_taxonomy" } ] }, { "name": "110 kDa actin filament-associated protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMC5/entry#names_and_taxonomy" } ] }, { "name": "actin filament-associated protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021328208", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328208" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133187) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021328208.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328208", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328208" } ] } ], "disease": [ { "disease_id": "DOID:1067", "recommended_name": { "id": "DOID:1067", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1067", "name": "open-angle glaucoma", "description": "A glaucoma characterized by optic nerve damage resulting in progressive loss of visual field and increased pressure in the eye due to trabecular blockage." }, "synonyms": [ { "id": "DOID:1067", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1067", "name": "Wide-angle glaucoma", "description": "" }, { "id": "DOID:1067", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1067", "name": "glaucoma simplex", "description": "" }, { "id": "DOID:1067", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1067", "name": "open angle glaucoma", "description": "" }, { "id": "DOID:1067", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1067", "name": "pigmentary glaucoma", "description": "" }, { "id": "MONDO:0008328", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008328", "name": "glaucoma 1, open angle, P", "description": "" }, { "id": "MONDO:0008328", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008328", "name": "glaucoma 1, open angle, P", "description": "" }, { "id": "MONDO:0008328", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008328", "name": "glaucoma 1, open angle, type P", "description": "" }, { "id": "MONDO:0008328", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008328", "name": "GLC1P", "description": "" }, { "id": "MONDO:0011222", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011222", "name": "obsolete glaucoma 1, open angle, D", "description": "" }, { "id": "MONDO:0011222", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011222", "name": "GLC1D", "description": "" }, { "id": "MONDO:0011222", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011222", "name": "glaucoma 1, open angle, D", "description": "" }, { "id": "MONDO:0011222", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011222", "name": "glaucoma 1D, primary open angle", "description": "" }, { "id": "MONDO:0011311", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011311", "name": "obsolete glaucoma 1, open angle, F", "description": "" }, { "id": "MONDO:0011311", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011311", "name": "glaucoma 1, open angle, F", "description": "" }, { "id": "MONDO:0011311", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011311", "name": "glaucoma 1, open angle, type F", "description": "" }, { 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"MONDO:0012101", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012101", "name": "GLC1J", "description": "" }, { "id": "MONDO:0012101", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012101", "name": "JOAG1J", "description": "" }, { "id": "MONDO:0012101", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012101", "name": "JOAG2", "description": "" }, { "id": "MONDO:0012101", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012101", "name": "glaucoma 1, open angle, J", "description": "" }, { "id": "MONDO:0012102", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012102", "name": "glaucoma 1, open angle, K", "description": "" }, { "id": "MONDO:0012102", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012102", "name": "GLC1K", "description": "" }, { "id": "MONDO:0012102", "resource": "MONDO", "url": 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"https://monarchinitiative.org/disease/MONDO:0012357", "name": "obsolete glaucoma 1, open angle, G", "description": "OBSOLETE. Any open-angle glaucoma in which the cause of the disease is a mutation in the WDR36 gene." }, { "id": "MONDO:0012357", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012357", "name": "WDR36 open-angle glaucoma", "description": "" }, { "id": "MONDO:0012357", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012357", "name": "glaucoma 1, open angle, G", "description": "" }, { "id": "MONDO:0012357", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012357", "name": "glaucoma 1, open angle, type G", "description": "" }, { "id": "MONDO:0012357", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012357", "name": "open-angle glaucoma caused by mutation in WDR36", "description": "" }, { "id": "MONDO:0012357", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012357", "name": "GLC1G", "description": "" }, { "id": "MONDO:0012515", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012515", "name": "glaucoma 1, open angle, M", "description": "" }, { "id": "MONDO:0012515", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012515", "name": "GLC1M", "description": "" }, { "id": "MONDO:0012515", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012515", "name": "JOAG1M", "description": "" }, { "id": "MONDO:0012515", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012515", "name": "glaucoma 1, open angle, M", "description": "" }, { "id": "MONDO:0012645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012645", "name": "glaucoma 1, open angle, N", "description": "" }, { "id": "MONDO:0012645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012645", "name": "GLC1N", "description": "" }, { "id": "MONDO:0012645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012645", "name": "JOAG1N", "description": "" }, { "id": "MONDO:0012645", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012645", "name": "glaucoma 1, open angle, N", "description": "" }, { "id": "MONDO:0012646", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012646", "name": "obsolete glaucoma 1, open angle, H", "description": "" }, { "id": "MONDO:0012646", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012646", "name": "GLC1H", "description": "" }, { "id": "MONDO:0012646", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012646", "name": "glaucoma 1, open angle, H", "description": "" }, { "id": "MONDO:0013134", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013134", "name": "glaucoma 1, open angle, O", "description": "Any open-angle glaucoma in which the cause of the disease is a mutation in the NTF4 gene." }, { "id": "MONDO:0013134", "resource": "MONDO", "url": 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"url": "https://www.uniprot.org/uniprotkb/A0A8M9Q3X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q3X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q3X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GXV7", "url": "https://www.uniprot.org/uniprotkb/A0AC58GXV7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GXV7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GXV7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GXW2", "url": "https://www.uniprot.org/uniprotkb/A0AC58GXW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GXW2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GXW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GXW7", "url": "https://www.uniprot.org/uniprotkb/A0AC58GXW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GXW7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GXW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100316-6", "url": "https://zfin.org/ZDB-GENE-100316-6", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRSDPILFASRAMEELLAELRVFLELLDREYLTAGVREKKQQILNILHRVLATREPSCKTEIHTSLPAPPQMPLPEIPHPWMPPDNGPPPLPSSSLPEGYYEEAVPLGPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGQKMRHQWPSEEASMDLVKDARICAFLLRKKRFGQWTKLLCVIKDNKLLCYKSSKDQTPQMELLLSGCSITHIPKDGKKKKHELKIVHQGADALVLAVQSKEQAEQWLKVMKEVCSNGNGVVDCDGAGSGSTVHKAELEKKLSCDRPSSDGEPCHENGISDGKDSAKGKKNSKSEQKGTVGRVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNNRWRERWCQLKDNQLFLHKDRADLKTHMASLPLRGCEVIPGLDSKHPFAFRLLRNGQEVAVLEASSSESMGRWLGVLLAETGSTTDPAALHYDYIDVETTANVIQLAKQSFCFTSKRAVSPNPYLDNPVNGYACPTGVALHYDDVPCINGTIPDAHYSSPASGGRRWKDESHYENTDLYENMPSPKLAARYSPKSTRTSSSSGHYSTPNSTKSLSSSSAANTNTNQMKGKKGLIANGFGAKKLDKNQPKKANGISSTLPVKRNNSSVDQYKYGKNRVEADAKKLQAKEEELMRKKQEIRNRLTQLKKDRKDLRTALENNTAKRSQASLTERLKKVEDECKLKEEERVSLELELTEVKESLKKALNGGVTLGLTIEPKTGSSSPQSPVLMRRTVDNSPISSCNTSDTETCSLPVNSASLLRRQTQQKASPVRGHVLRKAKEWEMKSGT", "length": 810, "header": "tr|A0A8M9PMC5-1|A0A8M9PMC5_DANRE Isoform 1 of Actin filament-associated protein 1 OS=Danio rerio OX=7955 GN=afap1 PE=4 SV=2 CANONICAL=A0A8M9PMC5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PMC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMC5/entry#A0A8M9PMC5-1", "sequence": { "sequence": "MRSDPILFASRAMEELLAELRVFLELLDREYLTAGVREKKQQILNILHRVLATREPSCKTEIHTSLPAPPQMPLPEIPHPWMPPDNGPPPLPSSSLPEGYYEEAVPLGPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGQKMRHQWPSEEASMDLVKDARICAFLLRKKRFGQWTKLLCVIKDNKLLCYKSSKDQTPQMELLLSGCSITHIPKDGKKKKHELKIVHQGADALVLAVQSKEQAEQWLKVMKEVCSNGNGVVDCDGAGSGSTVHKAELEKKLSCDRPSSDGEPCHENGISDGKDSAKGKKNSKSEQKGTVGRVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNNRWRERWCQLKDNQLFLHKDRADLKTHMASLPLRGCEVIPGLDSKHPFAFRLLRNGQEVAVLEASSSESMGRWLGVLLAETGSTTDPAALHYDYIDVETTANVIQLAKQSFCFTSKRAVSPNPYLDNPVNGYACPTGVALHYDDVPCINGTIPDAHYSSPASGGRRWKDESHYENTDLYENMPSPKLAARYSPKSTRTSSSSGHYSTPNSTKSLSSSSAANTNTNQMKGKKGLIANGFGAKKLDKNQPKKANGISSTLPVKRNNSSVDQYKYGKNRVEADAKKLQAKEEELMRKKQEIRNRLTQLKKDRKDLRTALENNTAKRSQASLTERLKKVEDECKLKEEERVSLELELTEVKESLKKALNGGVTLGLTIEPKTGSSSPQSPVLMRRTVDNSPISSCNTSDTETCSLPVNSASLLRRQTQQKASPVRGHVLRKAKEWEMKSGT", "length": 810, "header": "tr|A0A8M9PMC5-1|A0A8M9PMC5_DANRE Isoform 1 of Actin filament-associated protein 1 OS=Danio rerio OX=7955 GN=afap1 PE=4 SV=2 CANONICAL=A0A8M9PMC5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PTH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMC5/entry#A0A8M9PTH1-1", "sequence": { "sequence": "MTESNEEAMEELLAELRVFLELLDREYLTAGVREKKQQILNILHRVLATREPSCKTEIHTSLPAPPQMPLPEIPHPWMPPDNGPPPLPSSSLPEGYYEEAVPLGPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGQKMRHQWPSEEASMDLVKDARICAFLLRKKRFGQWTKLLCVIKDNKLLCYKSSKDQTPQMELLLSGCSITHIPKDGKKKKHELKIVHQGADALVLAVQSKEQAEQWLKVMKEVCSNGNGVVDCDGAGSGSTVHKAELEKKLSCDRPSSDGEPCHENGISDGKDSAKGKKNSKSEQKGTVGRVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNNRWRERWCQLKDNQLFLHKDRADLKTHMASLPLRGCEVIPGLDSKHPFAFRLLRNGQEVAVLEASSSESMGRWLGVLLAETGSTTDPAALHYDYIDVETTANVIQLAKQSFCFTSKRAVSPNPYLDNPVNGYACPTGVALHYDDVPCINGTIPDAHYSSPASGGRRWKDESHYENTDLYENMPSPKLAARYSPKSTRTSSSSGHYSTPNSTKSLSSSSAANTNTNQMKGKKGLIANGFGAKKLDKNQPKKANGISSTLPVKRNNSSVDQYKYGKNRVEADAKKLQAKEEELMRKKQEIRNRLTQLKKDRKDLRTALENNTAKRSQASLTERLKKVEDECKLKEEERVSLELELTEVKESLKKALNGGVTLGLTIEPKTGSSSPQSPVLMRRTVDNSPISSCNTSDTETCSLPVNSASLLRRQTQQKASPVRGHVLRKAKEWEMKSGT", "length": 806, "header": "tr|A0A8M9PTH1-1|A0A8M9PMC5_DANRE Computationally mapped isoform of Actin filament-associated protein 1 OS=Danio rerio OX=7955 GN=afap1 PE=4 SV=2 CANONICAL=A0A8M9PMC5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q3X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMC5/entry#A0A8M9Q3X7-1", "sequence": { "sequence": "MRSDPILFASRAMEELLAELRVFLELLDREYLTAGVREKKQQILNILHRVLATREPSCKTEIHTSLPAPPQMPLPEIPHPWMPPDNGPPPLPSSSLPEGYYEEAVPLGPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGQKMRHQWPSEEASMDLVKDARICAFLLRKKRFGQWTKLLCVIKDNKLLCYKSSKDQTPQMELLLSGCSITHIPKDGKKKKHELKIVHQGADALVLAVQSKEQAEQWLKVMKEVCSNGNGVVDCDGAGSGSTVHKAELEKKLSCDRPSSDGEPCHENGISDGKDSAKGKKNSKSEQKGTVGRVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNNRWRERWCQLKDNQLFLHKDRADLKTHMASLPLRGCEVIPGLDSKHPFAFRLLRNGQEVAVLEASSSESMGRWLGVLLAETGSTTDPAALHYDYIDVETTANVIQLAKQSFCFTSKRAVSPNPYLDNPVNGYACPTGVALHYDDVPCINGTMKGKKGLIANGFGAKKLDKNQPKKANGISSTLPVKRNNSSVDQYKYGKNRVEADAKKLQAKEEELMRKKQEIRNRLTQLKKDRKDLRTALENNTAKRSQASLTERLKKVEDECKLKEEERVSLELELTEVKESLKKALNGGVTLGLTIEPKTGSSSPQSPVLMRRTVDNSPISSCNTSDTETCSLPVNSASLLRRQTQQKASPVRGHVLRKAKEWEMKSGT", "length": 735, "header": "tr|A0A8M9Q3X7-1|A0A8M9PMC5_DANRE Computationally mapped isoform of Actin filament-associated protein 1 OS=Danio rerio OX=7955 GN=afap1 PE=4 SV=2 CANONICAL=A0A8M9PMC5-1" }, "locus": {} }, { "isoform_ac": "A0AC58GXV7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMC5/entry#A0AC58GXV7-1", "sequence": { "sequence": "MVMKEVCSNGNGVVDCDGAGSGSTVHKAELEKKLSCDRPSSDGEPCHENGISDGKDSAKGKKNSKSEQKGTVGRVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNNRWRERWCQLKDNQLFLHKDRADLKTHMASLPLRGCEVIPGLDSKHPFAFRLLRNGQEVAVLEASSSESMGRWLGVLLAETGSTTDPAALHYDYIDVETTANVIQLAKQSFCFTSKRAVSPNPYLDNPVNGYACPTGVALHYDDVPCINGTMKGKKGLIANGFGAKKLDKNQPKKANGISSTLPVKRNNSSVDQYKYGKNRVEADAKKLQAKEEELMRKKQEIRNRLTQLKKDRKDLRTALENNTAKRSQASLTERLKKVEDECKLKEEERVSLELELTEVKESLKKALNGGVTLGLTIEPKTGSSSPQSPVLMRRTVDNSPISSCNTSDTETCSLPVNSASLLRRQTQQKASPVRGHVLRKAKEWEMKSGT", "length": 487, "header": "tr|A0AC58GXV7-1|A0AC58GXV7_DANRE Computationally mapped isoform of Actin filament-associated protein 1 isoform X6 OS=Danio rerio OX=7955 GN=afap1 PE=4 SV=1 CANONICAL=A0A8M9PMC5-1" }, "locus": {} }, { "isoform_ac": "A0AC58GXW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMC5/entry#A0AC58GXW2-1", "sequence": { "sequence": "MVMKEVCSNGNGVVDCDGAGSGSTVHKAELEKKLSCDRPSSDGEPCHENGISDGKDSAKGKKNSKSEQKGTVGRVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNNRWRERWCQLKDNQLFLHKDRADLKTHMASLPLRGCEVIPGLDSKHPFAFRLLRNGQEVAVLEASSSESMGRWLGVLLAETGSTTDPAALHYDYIDVETTANVIQLAKQSFCFTSKRAVSPNPYLDNPVNGYACPTGVALHYDDVPCINGTIPDAHYSSPASGGRRWKDESHYENTDLYENMPSPKLAARYSPKSTRTSSSSGHYSTPNSTKSLSSSSAANTNTNQMKGKKGLIANGFGAKKLDKNQPKKANGISSTLPVKRNNSSVDQYKYGKNRVEADAKKLQAKEEELMRKKQEIRNRLTQLKKDRKDLRTALENNTAKRSQASLTERLKKVEDECKLKEEERVSLELELTEVKESLKKALNGGVTLGLTIEPKTGSSSPQSPVLMRRTVDNSPISSCNTSDTETCSLPVNSASLLRRQTQQKASPVRGHVLRKAKEWEMKSGT", "length": 562, "header": "tr|A0AC58GXW2-1|A0AC58GXW2_DANRE Computationally mapped isoform of Actin filament-associated protein 1 isoform X5 OS=Danio rerio OX=7955 GN=afap1 PE=4 SV=1 CANONICAL=A0A8M9PMC5-1" }, "locus": {} }, { "isoform_ac": "A0AC58GXW7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMC5/entry#A0AC58GXW7-1", "sequence": { "sequence": "MTESNEEAMEELLAELRVFLELLDREYLTAGVREKKQQILNILHRVLATREPSCKTEIHTSLPAPPQMPLPEIPHPWMPPDNGPPPLPSSSLPEGYYEEAVPLGPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGQKMRHQWPSEEASMDLVKDARICAFLLRKKRFGQWTKLLCVIKDNKLLCYKSSKDQTPQMELLLSGCSITHIPKDGKKKKHELKIVHQGADALVLAVQSKEQAEQWLKVMKEVCSNGNGVVDCDGAGSGSTVHKAELEKKLSCDRPSSDGEPCHENGISDGKDSAKGKKNSKSEQKGTVGRVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNNRWRERWCQLKDNQLFLHKDRADLKTHMASLPLRGCEVIPGLDSKHPFAFRLLRNGQEVAVLEASSSESMGRWLGVLLAETGSTTDPAALHYDYIDVETTANVIQLAKQSFCFTSKRAVSPNPYLDNPVNGYACPTGVALHYDDVPCINGTMKGKKGLIANGFGAKKLDKNQPKKANGISSTLPVKRNNSSVDQYKYGKNRVEADAKKLQAKEEELMRKKQEIRNRLTQLKKDRKDLRTALENNTAKRSQASLTERLKKVEDECKLKEEERVSLELELTEVKESLKKALNGGVTLGLTIEPKTGSSSPQSPVLMRRTVDNSPISSCNTSDTETCSLPVNSASLLRRQTQQKASPVRGHVLRKAKEWEMKSGT", "length": 731, "header": "tr|A0AC58GXW7-1|A0AC58GXW7_DANRE Computationally mapped isoform of Actin filament-associated protein 1 OS=Danio rerio OX=7955 GN=afap1 PE=4 SV=1 CANONICAL=A0A8M9PMC5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:568356", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568356", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q80YS6-1", "protein_name": "Actin filament-associated protein 1", "gene_name": "Afap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEELIVELRLFLELLDHEYLTSTVREKKAVLTNILLRLQSSKGFEVKDHAQKAEANNLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCSITYIPRDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDPECSPPPSTSAPVNKAELEKKLSSERPSSDGEGGVENGVTTCNGKEQAKRKKPSKSEAKGTVSKVTGKKITKIIGLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDSKLILHKDRADLKTHLVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPGALHYDYIDVEMSANVIQTAKQTFCFMNRRAVSTSPYLGSLSNGYAHPSGTALHYDDVPCVNGSLKNKKPPASSNGVPVKGKAPSSQQKKVETAGGVKRTASNAEQYKYGKNRVEADAKRLQSKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKTQAALEDKLKRLEEECKQREAERVSLELELTEVKESLKKALAGGVTLGLAIEPRSGTSSPQSPVFRHRTLENSPISSCDTSDAEGPLPVNSAAVLKKSQPSSGSSPCRGHVLQKAKEWELKNGT", "length": 731 }, "evidence": [ { "id": "HGNC:24017", "url": "https://alliancegenome.org/gene/HGNC:24017#orthology", "database": "AGR" }, { "id": "MGI:1917542", "url": "https://alliancegenome.org/gene/MGI:1917542#orthology", "database": "AGR" }, { "id": "RGD:619959", "url": "https://alliancegenome.org/gene/RGD:619959#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100316-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100316-6#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N556-1", "protein_name": "Actin filament-associated protein 1", "gene_name": "AFAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEELIVELRLFLELLDHEYLTSTVREKKAVITNILLRIQSSKGFDVKDHAQKQETANSLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNYDSDAMSSSYESYDEEEEDGKGKKTRHQWPSEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCNITYIPKDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDSECPPPPSSPVHKAELEKKLSSERPSSDGEGVVENGITTCNGKEQVKRKKSSKSEAKGTVSKVTGKKITKIISLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDNKLIFHKDRTDLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPEALHYDYIDVEMSASVIQTAKQTFCFMNRRVISANPYLGGTSNGYAHPSGTALHYDDVPCINGSLKGKKPPVASNGVTGKGKTLSSQPKKADPAAVVKRTGSNAAQYKYGKNRVEADAKRLQTKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKPQAILEEKLKQLEEECRQKEAERVSLELELTEVKESLKKALAGGVTLGLAIEPKSGTSSPQSPVFRHRTLENSPISSCDTSDTEGPVPVNSAAVLKKSQAAPGSSPCRGHVLRKAKEWELKNGT", "length": 730 }, "evidence": [ { "id": "HGNC:24017", "url": "https://alliancegenome.org/gene/HGNC:24017#orthology", "database": "AGR" }, { "id": "MGI:1917542", "url": "https://alliancegenome.org/gene/MGI:1917542#orthology", "database": "AGR" }, { "id": "RGD:619959", "url": "https://alliancegenome.org/gene/RGD:619959#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100316-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100316-6#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VH46-1", "protein_name": "Actin filament-associated protein 1", "gene_name": "Afap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEELIVELRLFLELLDHEYLTSTVREKKAVLTNILLRMQSSKGFEVKDHAQKAETNNLPAPPQMPLPEIPQPWLPPDSGPPPLPTSSLPEGYYEEAVPLSPGKAPEYITSNYDSEAMGSSYESYDEEEEDGKGKKTQHQCHHEEASMDLVKDAKICAFLLRKKRFGQWTKLLCVIKDTKLLCYKSSKDQQPQMELPLQGCSITYIPRDSKKKKHELKITQQGTDPLVLAVQSKEQAEQWLKVIKEAYSGCSGPVDPECSPPPSASVPVNKAELEKKLSSERPSSDGEGVVENGVTTCNGKEQAKRKKPSKSEAKGTVSKVTGKKITKIIGLGKKKPSTDEQTSSAEEDVPTCGYLNVLSNSRWRERWCRVKDSKLILHKDRADLKTHIVSIPLRGCEVIPGLDSKHPLTFRLLRNGQEVAVLEASSSEDMGRWIGILLAETGSSTDPGALHYDYIDVEMSANVIQTAKQTFCFMNRRAVSTSPYLGSLSNGYAHPSGTALHYDDVPCVNGSLKNKKPPASSNGLPVKGRAPSSQQKKVESAGGVKRTASNAEQYKYGKNRVEADAKRLQSKEEELLKRKEALRNRLAQLRKERKDLRAAIEVNAGRKTQVALEDKLKRLEEECKQREAERVSLELELTEVKESLKKALAGGVTLGLAIEPKSGTSSPQSPVFRHRTLENSPISSCDTSDAEGPLPVNSAAVLKKSQPSSSSSPCRGHVLQKAREWELKNGT", "length": 731 }, "evidence": [ { "id": "HGNC:24017", "url": "https://alliancegenome.org/gene/HGNC:24017#orthology", "database": "AGR" }, { "id": "MGI:1917542", "url": "https://alliancegenome.org/gene/MGI:1917542#orthology", "database": "AGR" }, { "id": "RGD:619959", "url": "https://alliancegenome.org/gene/RGD:619959#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100316-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100316-6#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMC5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMC5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMC5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 572, "end_pos": 574, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 627, "end_pos": 629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 765, "end_pos": 767, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PMC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMC5" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 160, "end_pos": 256, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 512, "end_pos": 514 }, { "start_pos": 572, "end_pos": 574 }, { "start_pos": 626, "end_pos": 628 }, { "start_pos": 627, "end_pos": 629 }, { "start_pos": 681, "end_pos": 683 }, { "start_pos": 765, "end_pos": 767 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329158" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQ51", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ51" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC558805", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ51", "locus": {} } ], "crossref": [ { "id": "A0A8M9PQ51", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PQ51", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "558805", "url": "https://www.ncbi.nlm.nih.gov/gene/558805", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558805", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558805", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021329158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329158", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PQ51", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ51", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQ51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ51-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTKAISLLLSVTLISLALTGAFGADIINGKKAKKSSLLYMASVQINGEHKCGGFLIDPSYVLTAAHCNKQGNMSVILGTHDISPKGTNVKRYRVQNKHIHPSYKSVKTGKDIMLLKLYKKVKIGKDVKLVTIPSKDKPLKPKSKCLVAGWGKTEKDNTVNDLLVTDVLTINKTVCQSVWKKINVELPDNILCAGGYETKSGACQGDSGGPLVCSGQAVGIVSFNMGRCDYPNTPNIYTQISKYTHWIKKVIRGGS", "length": 255, "header": "tr|A0A8M9PQ51-1|A0A8M9PQ51_DANRE Isoform 1 of Mast cell protease 4 OS=Danio rerio OX=7955 GN=LOC558805 PE=4 SV=1 CANONICAL=A0A8M9PQ51-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PQ51-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ51/entry#A0A8M9PQ51-1", "sequence": { "sequence": "MTKAISLLLSVTLISLALTGAFGADIINGKKAKKSSLLYMASVQINGEHKCGGFLIDPSYVLTAAHCNKQGNMSVILGTHDISPKGTNVKRYRVQNKHIHPSYKSVKTGKDIMLLKLYKKVKIGKDVKLVTIPSKDKPLKPKSKCLVAGWGKTEKDNTVNDLLVTDVLTINKTVCQSVWKKINVELPDNILCAGGYETKSGACQGDSGGPLVCSGQAVGIVSFNMGRCDYPNTPNIYTQISKYTHWIKKVIRGGS", "length": 255, "header": "tr|A0A8M9PQ51-1|A0A8M9PQ51_DANRE Isoform 1 of Mast cell protease 4 OS=Danio rerio OX=7955 GN=LOC558805 PE=4 SV=1 CANONICAL=A0A8M9PQ51-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:558805", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558805", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQ51", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ51" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQ51", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ51" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PQ51", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ51" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 252, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 72, "end_pos": 74 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PQX2-1", "uniprot_ac": "A0A8M9PQX2", "uniprot_id": "A0A8M9PQX2_DANRE", "mass": { "chemical_mass": 67182.0, "monoisotopic_mass": 67182.0 }, "refseq": { "ac": "XP_073795506", "name": "podocan isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073795506" }, "gene_names": [ { "name": "podn", "type": "recommended", "evidence": [ { "id": "A0A8M9PQX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQX2" } ] }, { "name": "podn", "type": "synonym", "evidence": [ { "id": "XP_073795506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073795506" } ] } ], "protein_names": [ { "name": "Podocan isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PQX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQX2/entry#names_and_taxonomy" } ] }, { "name": "podocan isoform X1", "type": "synonym", "evidence": [ { "id": "XP_073795506", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073795506" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073795506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073795506" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQX2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQX2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "podn", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQX2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100922-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100922-117", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PQX2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PQX2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100536479", "url": "https://www.ncbi.nlm.nih.gov/gene/100536479", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100536479", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536479", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073795506", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073795506", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PQX2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMT2", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMT2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100922-117", "url": "https://zfin.org/ZDB-GENE-100922-117", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDERCGLLELMCLLLLGWTLIVRGQTETDLHLLDEEEAEEVKNAEEKVSCPEKCSCSGEGAVDCNGVSLSEFPQDLSEQTRQLSLQNNQISEVTLEHLSRLQQLETLNLQNNRLTTQGLEDEGFDILERLSYLYLANNKLTAAPRHLPPSLVSADFAANQLTKIFPNTFGQKPALKSVYLHNNKLTDAGLPESMFNGSDSLEILIMSSNFLRYVPKYLPTALYRLHLKNNKLEKIPSGAFDNLFHLRELYLQNNFLSNDGMDNETFSHLNSLEYLDLSNNNLSTVPLGLPRNVILLHLEKNSIQSIAVNALSPIRNLEYLLLHNNRLRSRSIHPAAFQGLKRLHTVHMYNNLLERVPRGLPRRAKTLMLLHNLISEIGRNDLITLYTLTELNLSYNRLTSAKLHREAFRKLRILETLDLSGNKLQALPLGLPKSLQILKVKDNQMTEIPEGALLGMTSLRELYLTNNQLKLSSIYQGAWLEMNALKTLDLSGNMLSHIPPDLPESLEFLHLQNNRINSISETAFLNTPNIKGIFLRFNRLSVNSVSEETFAHLSKLRVLDIGHGNISPNRGQAGDNMEEEEEELTQEEEETQP", "length": 593, "header": "tr|A0A8M9PQX2-1|A0A8M9PQX2_DANRE Isoform 1 of Podocan isoform X1 OS=Danio rerio OX=7955 GN=podn PE=4 SV=2 CANONICAL=A0A8M9PQX2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PQX2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQX2/entry#A0A8M9PQX2-1", "sequence": { "sequence": "MDERCGLLELMCLLLLGWTLIVRGQTETDLHLLDEEEAEEVKNAEEKVSCPEKCSCSGEGAVDCNGVSLSEFPQDLSEQTRQLSLQNNQISEVTLEHLSRLQQLETLNLQNNRLTTQGLEDEGFDILERLSYLYLANNKLTAAPRHLPPSLVSADFAANQLTKIFPNTFGQKPALKSVYLHNNKLTDAGLPESMFNGSDSLEILIMSSNFLRYVPKYLPTALYRLHLKNNKLEKIPSGAFDNLFHLRELYLQNNFLSNDGMDNETFSHLNSLEYLDLSNNNLSTVPLGLPRNVILLHLEKNSIQSIAVNALSPIRNLEYLLLHNNRLRSRSIHPAAFQGLKRLHTVHMYNNLLERVPRGLPRRAKTLMLLHNLISEIGRNDLITLYTLTELNLSYNRLTSAKLHREAFRKLRILETLDLSGNKLQALPLGLPKSLQILKVKDNQMTEIPEGALLGMTSLRELYLTNNQLKLSSIYQGAWLEMNALKTLDLSGNMLSHIPPDLPESLEFLHLQNNRINSISETAFLNTPNIKGIFLRFNRLSVNSVSEETFAHLSKLRVLDIGHGNISPNRGQAGDNMEEEEEELTQEEEETQP", "length": 593, "header": "tr|A0A8M9PQX2-1|A0A8M9PQX2_DANRE Isoform 1 of Podocan isoform X1 OS=Danio rerio OX=7955 GN=podn PE=4 SV=2 CANONICAL=A0A8M9PQX2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IMT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQX2/entry#A0AC58IMT2-1", "sequence": { "sequence": "MRNNQISEVTLEHLSRLQQLETLNLQNNRLTTQGLEDEGFDILERLSYLYLANNKLTAAPRHLPPSLVSADFAANQLTKIFPNTFGQKPALKSVYLHNNKLTDAGLPESMFNGSDSLEILIMSSNFLRYVPKYLPTALYRLHLKNNKLEKIPSGAFDNLFHLRELYLQNNFLSNDGMDNETFSHLNSLEYLDLSNNNLSTVPLGLPRNVILLHLEKNSIQSIAVNALSPIRNLEYLLLHNNRLRSRSIHPAAFQGLKRLHTVHMYNNLLERVPRGLPRRAKTLMLLHNLISEIGRNDLITLYTLTELNLSYNRLTSAKLHREAFRKLRILETLDLSGNKLQALPLGLPKSLQILKVKDNQMTEIPEGALLGMTSLRELYLTNNQLKLSSIYQGAWLEMNALKTLDLSGNMLSHIPPDLPESLEFLHLQNNRINSISETAFLNTPNIKGIFLRFNRLSVNSVSEETFAHLSKLRVLDIGHGNISPNRGQAGDNMEEEEEELTQEEEETQP", "length": 509, "header": "tr|A0AC58IMT2-1|A0AC58IMT2_DANRE Computationally mapped isoform of Podocan isoform X2 OS=Danio rerio OX=7955 GN=podn PE=4 SV=1 CANONICAL=A0A8M9PQX2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100536479", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536479", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZY32-1", "protein_name": "Podocan-like 1", "gene_name": "Podnl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLDKSLGRGTAGLTMRPQELLLLLLLLRWPAAHTEDPAFPHLGDSSQPLPRPCPWRCSCPRDDTVDCAGLDLRVFPDNITRAARHLSLQKNQLQELPYNELSRLSGLRTLDLHSNLISSEGLPDEAFESLTQLENFYVAHNKLSVAPQFLPRSLRVADLAANEVVEIFPLTFGEKPALRSVYLHNNRLRNTGLPPNTFHGSEAITTLSLSSNQLRYLPPSLPASLERLHLQNNLISKVPRGALSLQTQLRELYLQHNQLTDSGLDATTFSKLSSLEYLDLSHNQLATVPEGLPGNLTILHLGRNCIRHVEAIRLHKAKGLRYLLLQHNKLEASALPAGTLRPLRALHTLHLYGNRLERVPPALPRHLQALVMPHNRVAALGARDLVSARALTELNLAYNRLASAHVHPGAFRRLRALRSLDLAGNQLSRLPEGLPASLRSLRLQRNQLRTLEPEQLAGLNKLRELNLAHNRLRVGDIEPGAWHELQALQVLDLSHNELSFVPPDLPEALEELYLQANRISHVGPEAFLSTPHLRALSLRANRLHMTSIAAEAFRGLAHLRVVDTAENLEQVLIQLPRKGKEP", "length": 582 }, "evidence": [ { "id": "RGD:1307753", "url": "https://alliancegenome.org/gene/RGD:1307753#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100922-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100922-117#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P11915-1", "protein_name": "Sterol carrier protein 2", "gene_name": "Scp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPSVALNSPRLPRVFVVGVGMTKFMKPGGENSRDYPDLAKEAGQKALADRQIPYSAVEQACVGYVYGESTCGQRAIYHSLGLTGIPIINVNNNCSTGSTALFMAQQLVQGGLANCVLALGFEKMEKGSLGTKYSDRSNPLEKHIDVLINKYGMSACPFAPQLFGSAGKEHMETYGTKVEHFAKIGWKNHKHSVNNPYSQFQDEYSLDEIMKSRPVFDFLTVLQCCPTSDGAAAAIVSSEEFVQKHGLQSKAVEIVAQEMVTDMPSTFEEKSVIKMVGYDMSKEAARKCYEKSGLGPSDVDVIELHDCFSTNELLTYEALGLCPEGQGGALVDRGDNTYGGKWVINPSGGLISKGHPLGATGLAQCAELCWQLRGEAGKRQVPGAKVALQHNLGLGGAAVVTLYRMGFPEAASSFRTHQISAAPTSSAGDGFKANLIFKEIEKKLEEEGEEFVKKIGGIFAFKVKDGPGGKEATWVVDVKNGKGSVLPDSDKKADCTITMADSDLLALMTGKMNPQSAFFQGKLKIAGNMGLAMKLQSLQLQPDKAKL", "length": 547 }, "evidence": [ { "id": "HGNC:23174", "url": "https://alliancegenome.org/gene/HGNC:23174#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P3Y9-1", "protein_name": "Podocan-like protein 1", "gene_name": "Podnl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPQELLLLLLMLKWSLAHTEDPAFPHLGDSSQPLPRPCPWRCSCPRDDTVDCAGLDLRIFPDNITRAARHLSLQNNQLRELPYNELSRLSGLRTLDLHSNLITSEGLPDEAFESLNQLENFYVAHNKLSVAPQFLPRSLRVADLAANEVVEIFPLTFGEKPALRSVYLHNNRLRNTGLPPNTFHGSEVITTLSLSSNQLSYLPPSLPASLERLHLQNNLISKVPRGALSLQTHLRELYLQHNQLTDSGLDATTFSKLSSLEYLDLSHNQLATVPEGLPGTLTILHLGRNCIRHVEAVRLHKARGLRYLLLQHNKLGASALPKGTLRPLRALHTLHLYGNKLERVPPALPRHLQALVMPHNHVAALGARDLVSARALAELNLAYNSLASAHVHPSAFRRLRALRSLDLAGNQLTRLPEGLPASLRSLRLQRNQLRTLEPEQLAGLNKLRELNLAHNRLRVGDIGPGTWHELQALKVLDLSHNELSFVPPDLPEALEELYLQANRISHVGPEAFLSTPHLRALFLRANRLHMTSIRAEALQGLTHLRVVDTAENPEQVLV", "length": 559 }, "evidence": [ { "id": "RGD:1307753", "url": "https://alliancegenome.org/gene/RGD:1307753#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6PEZ8-1", "protein_name": "Podocan-like protein 1", "gene_name": "PODNL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWPSLLLLLLLPGPPPVAGLEDAAFPHLGESLQPLPRACPLRCSCPRVDTVDCDGLDLRVFPDNITRAAQHLSLQNNQLQELPYNELSRLSGLRTLNLHNNLISSEGLPDEAFESLTQLQHLCVAHNKLSVAPQFLPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAFRGSEAIATLSLSNNQLSYLPPSLPPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSGLDATTFSKLHSLEYLDLSHNQLTTVPAGLPRTLAILHLGRNRIRQVEAARLHGARGLRYLLLQHNQLGSSGLPAGALRPLRGLHTLHLYGNGLDRVPPALPRRLRALVLPHNHVAALGARDLVATPGLTELNLAYNRLASARVHHRAFRRLRALRSLDLAGNQLTRLPMGLPTGLRTLQLQRNQLRMLEPEPLAGLDQLRELSLAHNRLRVGDIGPGTWHELQALQVRHRLVSHTVPRAPPSPCLPCHVPNILVSW", "length": 505 }, "evidence": [ { "id": "RGD:1307753", "url": "https://alliancegenome.org/gene/RGD:1307753#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TQ62-1", "protein_name": "Podocan", "gene_name": "Podn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSRGLPLLLLVLQLFLGPVLPVRAPVFGRSDTPTLSPEENEFVEEENQPVLVLSSEEPEPGPATVDCPRDCACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLQRLETLNLQNNRLTSRGLPEEAFEHLTSLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDHMFNGSSNVEILILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSNLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIQSVEADVLTPIRNLEYLLLHSNQLQAKGIHPLAFQGLKKLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQMHRDAFRKLRLLRSLDLSGNRLQTLPPGLPKNVHVLKVKRNELAALARGALAGMAQLRELYLTGNRLRSRALGPRAWVDLAGLQLLDIAGNQLTEVPEGLPPSLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVESAFRRLKHLQVLDIEGNFEFGNGSKDKDEEEEEEEEEEDEEEETR", "length": 611 }, "evidence": [ { "id": "HGNC:23174", "url": "https://alliancegenome.org/gene/HGNC:23174#orthology", "database": "AGR" }, { "id": "MGI:2674939", "url": "https://alliancegenome.org/gene/MGI:2674939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100922-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100922-117#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z5L7-1", "protein_name": "Podocan", "gene_name": "PODN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQSRVLLLLLLLPPQLHLGPVLAVRAPGFGRSGGHSLSPEENEFAEEEPVLVLSPEEPGPGPAAVSCPRDCACSQEGVVDCGGIDLREFPGDLPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKAFEHLTNLNYLYLANNKLTLAPRFLPNALISVDFAANYLTKIYGLTFGQKPNLRSVYLHNNKLADAGLPDNMFNGSSNVEVLILSSNFLRHVPKHLPPALYKLHLKNNKLEKIPPGAFSELSSLRELYLQNNYLTDEGLDNETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLHLEKNAIRSVDANVLTPIRSLEYLLLHSNQLREQGIHPLAFQGLKRLHTVHLYNNALERVPSGLPRRVRTLMILHNQITGIGREDFATTYFLEELNLSYNRITSPQVHRDAFRKLRLLRSLDLSGNRLHTLPPGLPRNVHVLKVKRNELAALARGALVGMAQLRELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPEGLPESLEYLYLQNNKISAVPANAFDSTPNLKGIFLRFNKLAVGSVVDSAFRRLKHLQVLDIEGNLEFGDISKDRGRLGKEKEEEEEEEEEEEETR", "length": 613 }, "evidence": [ { "id": "HGNC:23174", "url": "https://alliancegenome.org/gene/HGNC:23174#orthology", "database": "AGR" }, { "id": "MGI:2674939", "url": "https://alliancegenome.org/gene/MGI:2674939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100922-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100922-117#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 263, "end_pos": 265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 281, "end_pos": 283, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PQX2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQX2" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 82, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 263, "end_pos": 265 }, { "start_pos": 281, "end_pos": 283 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 565, "end_pos": 567 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PRC5-1", "uniprot_ac": "A0A8M9PRC5", "uniprot_id": "A0A8M9PRC5_DANRE", "mass": { "chemical_mass": 108296.0, "monoisotopic_mass": 108296.0 }, "refseq": { "ac": "XP_021329578", "name": "FHF complex subunit HOOK-interacting protein 1A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329578" }, "gene_names": [ { "name": "fhip1aa", "type": "recommended", "evidence": [ { "id": "A0A8M9PRC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRC5" } ] }, { "name": "fhip1aa", "type": "synonym", "evidence": [ { "id": "XP_021329578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329578" } ] } ], "protein_names": [ { "name": "FHF complex subunit HOOK-interacting protein 1A", "type": "synonym", "evidence": [ { "id": "XP_021329578", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329578" }, { "id": "A0A8M9PRC5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRC5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329578" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRC5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRC5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fhip1aa", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRC5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090312-132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-132", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100000787", "url": "https://www.ncbi.nlm.nih.gov/gene/100000787", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100000787", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000787", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR21705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21705:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21705:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19311", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19311", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19314", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19314", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021329578", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329578", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PRC5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PRC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090312-132", "url": "https://zfin.org/ZDB-GENE-090312-132", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTSMVYNGNRGGQTLVLTGVDPETCMIVFKNHWAQVVKILEKHDPLRSNTGGLGGGHGLAGGGGLGSFRFGPIPGDEASAVQNYVEHMLFLLMEEECGQNGAMGPILEFVVMENVLERLFIWSLRREFTDDMKLEQLKMYEMLIGQARQPLLHHKPVLKPLMMLLSSCSGSPTGPSSPAVETELVLLLNQLCCVLAKDPSVLELFFHTSEDQGAANFLIFSLLIPFIHREGSVGQQARDALLLIMALSAENHVVAKHIAENTYFCPVLATGLSGLYSSLPTKLDVPSEEWHCLHRDDWQQLPALVQFLNSLEFCNAVIQVAHPSIRDQLVGYIHNGFLVPVLAPALHKLTLEEVMTTTAYLDLFIRSVSEPALLHTFLSFILLHRHDSVHILDTLVSRINTPFQLGTVSLALFRTLIGLYCEDVMLQLIFKYLIPCNHMMLSQRRVLNERDCYSVSAAKILALTPSCCSPEIFPPPLRQLDSILWSKGTDGSQTGTMETKETLLAEDDCVIGSEIYLDVSYLHYLYDARNSISHCMRACSVWSAPYNGENPPPEEYQRSTLEEANRTRSSVATRKKTNSVHNSGPPLKDLSATPGLLDLEWDDSYDACPAQVHTEEDQETRHIPDEPPEHIQELRRTAIMFVKGSYIEESEFQNDVMVYNLVAQKDANDSGNNYRDPSKPTEPEKQEVLDGRTTDQKAKNSESSINNGLNSPVNEMDSKKRGLQSDHKLQGPEGEDLMAQYEELIRTLGAQPNSPTKADSELKSRVDLIDDEEDEMDFNSFSPETPEAEKLPSPFGTKPRSGSKGHAVPFTGPFVSVLLSRLENMPSNTLHVNLLLTGILAQLAAYPQPLLRSFLLNTNLVFQPSVRSLYQVLASVKNQIDVWSSKNKDSSELLTAAQHCLLARESSLRDPQSSQAEDASEADRIKRNSAIQPKTVVPLSKTEVYATVLFAEFLKELAAIAQEHSILSHLPTEQ", "length": 974, "header": "tr|A0A8M9PRC5-1|A0A8M9PRC5_DANRE Isoform 1 of FHF complex subunit HOOK-interacting protein 1A OS=Danio rerio OX=7955 GN=fhip1aa PE=3 SV=1 CANONICAL=A0A8M9PRC5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PRC5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRC5/entry#A0A8M9PRC5-1", "sequence": { "sequence": "MTSMVYNGNRGGQTLVLTGVDPETCMIVFKNHWAQVVKILEKHDPLRSNTGGLGGGHGLAGGGGLGSFRFGPIPGDEASAVQNYVEHMLFLLMEEECGQNGAMGPILEFVVMENVLERLFIWSLRREFTDDMKLEQLKMYEMLIGQARQPLLHHKPVLKPLMMLLSSCSGSPTGPSSPAVETELVLLLNQLCCVLAKDPSVLELFFHTSEDQGAANFLIFSLLIPFIHREGSVGQQARDALLLIMALSAENHVVAKHIAENTYFCPVLATGLSGLYSSLPTKLDVPSEEWHCLHRDDWQQLPALVQFLNSLEFCNAVIQVAHPSIRDQLVGYIHNGFLVPVLAPALHKLTLEEVMTTTAYLDLFIRSVSEPALLHTFLSFILLHRHDSVHILDTLVSRINTPFQLGTVSLALFRTLIGLYCEDVMLQLIFKYLIPCNHMMLSQRRVLNERDCYSVSAAKILALTPSCCSPEIFPPPLRQLDSILWSKGTDGSQTGTMETKETLLAEDDCVIGSEIYLDVSYLHYLYDARNSISHCMRACSVWSAPYNGENPPPEEYQRSTLEEANRTRSSVATRKKTNSVHNSGPPLKDLSATPGLLDLEWDDSYDACPAQVHTEEDQETRHIPDEPPEHIQELRRTAIMFVKGSYIEESEFQNDVMVYNLVAQKDANDSGNNYRDPSKPTEPEKQEVLDGRTTDQKAKNSESSINNGLNSPVNEMDSKKRGLQSDHKLQGPEGEDLMAQYEELIRTLGAQPNSPTKADSELKSRVDLIDDEEDEMDFNSFSPETPEAEKLPSPFGTKPRSGSKGHAVPFTGPFVSVLLSRLENMPSNTLHVNLLLTGILAQLAAYPQPLLRSFLLNTNLVFQPSVRSLYQVLASVKNQIDVWSSKNKDSSELLTAAQHCLLARESSLRDPQSSQAEDASEADRIKRNSAIQPKTVVPLSKTEVYATVLFAEFLKELAAIAQEHSILSHLPTEQ", "length": 974, "header": "tr|A0A8M9PRC5-1|A0A8M9PRC5_DANRE Isoform 1 of FHF complex subunit HOOK-interacting protein 1A OS=Danio rerio OX=7955 GN=fhip1aa PE=3 SV=1 CANONICAL=A0A8M9PRC5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100000787", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000787", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GM32-1", "protein_name": "FHF complex subunit HOOK interacting protein 1A", "gene_name": "Fhip1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMSSVSTESKLQQAVSLKGVDPETCMIVFKNHWAQVVLAILQVVKILEKHDPLKNIQAKYGSIPPDEASAVQNYVEHMLFLLIEEQAKDAAMGPILEFVVCENIMEKLFLWSLRREFTDETKLEQLKMYEMLVTQSYQPLLHHKPILKPLMMLLSSCSGTATPAVEGKLVVLLNQLCSILAKDPSILELFFHTSEDQGAANFLIFSLLIPFIHREGTVGQQARDALLFIMSLSAENSMVANHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPALVQFMNSLEFCNAVIQVAHPLIRTQLVSYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHQHENVHILDTLTSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLVLRYLVPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCASGITLTLGNQERDYILWSKCMHDGSGPEEQPLPETPCSPSSPPPPPQPAPAACIVEYGKALDISYLQYLWEAHTNILHCMRDCRVWSALYDGDSPDPETFLQSLSEESRENSSHPEARLSQQCIRTSGQTKDKSQSELEWDDSYDTGISSGADVGSPGPYDDVETPAPPAPIDPPKHIQEMKKNAILLFKGSYIEESDFQDDVMVYRLCAEKDAEDTREPQGATTDPPAEAQPKAQPEAQSLPTSNGPLFSPNPEAESKPGRESSDLCQNMFSEAKPESEPGVALDSDSELTVPTFEAEPQSDSPVASTEGEDFIAQYDQIIQELDSGTEGLTEQSVPASEPSLLTHADEGRTECKAEEEEEDDDFDSLMADTPAEEAAPSPFGVGEDTATFTSRHPTRTQGTPFTGPFLSVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPVALTKDPIQEISRPESDKTLTDGPPRVLQPFLGNRAQMTKAPPNLPLPVKNTMLAAALFPEFLKELAALAQEHSILCYKILGDLEDSCC", "length": 1050 }, "evidence": [ { "id": "HGNC:34237", "url": "https://alliancegenome.org/gene/HGNC:34237#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-132#orthology", "database": "AGR" }, { "id": "RGD:1565007", "url": "https://alliancegenome.org/gene/RGD:1565007#orthology", "database": "AGR" }, { "id": "MGI:2444746", "url": "https://alliancegenome.org/gene/MGI:2444746#orthology", "database": "AGR" }, { "id": "FB:FBgn0025681", "url": "https://alliancegenome.org/gene/FB:FBgn0025681#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0V207-1", "protein_name": "FHF complex subunit HOOK-interacting protein 1B", "gene_name": "fhip1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSWLSRLNPRGPGTRTGRHAAPSSPCTADPETCLMVFENHWRQVSGVLKQRESSVGGFADDLTAVRNHTDQMLCLLAEERPAGGDIDSPAMGPILEMVVAENILEELVQWHVCRGLDPDSQLELLKLFEMLIGQSHQPLLLHSAVLQPLLSLLGACVDPQMGCPPALESSLVLLLNQVCVSMAKETAVLELLFRCGSVQQGPTNLLIFSLLVPFIHRDGALGQQARDALLLVMATSASNHAVARHITENSYFCPVLATGLSGLYSSLPRKIEVRGDDWHALRREDWIGVSSLVLFMNSLEFCNAVVQVAHPLVRCQLLDYLHNGFLVPVMGPALHKSSVDEMIASTAYLDLFLRCITETSLLKTFLRFILLHHHDNDTILDTLLTRISSNSRLCMVSLSLFKTLLSLNCEDLMLQLVLRYLLPCTHVMLSQRRAVRETDLYGKSADKFLSLIPECCRITSAPSGERDEEPAFWGKVLGSPTSESPVHPRPSTPSRLALFIRQQSSGGQANPSSSGSENAPSSPRGSVSSPLSPDSPMHQLSDFSEGETGYLEYLRDARKGIELCSWGCRDWSAPYDGENPSPNSAPLPPPPPTSNPSLSMVQEHFSVMDPTQQRAAVVAAARAEWSSSDRDSGEWDVTISKNCISLTPRSKKRSLLPSSIPLQSSSSASVSTEITGASETVYQHSRSTPHPALYNGMGQVEFTDSVDERMEAKKVKRDSDVNSGMVETGMNGSMGPVDYNDFHVGSTLKSSQVQLKPHLQHHTSVPSSTQECLPTESHRLSPVLGLTESSAASRGSESVERLIEELLERAPSEPLSGDSKCQGISIEAFHQELRELEERVRERRVSSRSSEESSRESRTAPLPSLTDEDCLPVETEQRSSETKPDSSTTGVFSPARPLGQPLAQPYTGPFITVLFSKLENMMQNSLYVNILLTGVVFQLACYPQPLLRSFLLNANMVFQPSVKSLIQVLGTVKNRIEVFAAAHEDFPAMLRKARRFLVARGKLDWSDSAMGVPSLRRSDSLIKSRKPSLGDLILRHTNSPTRARHAAQLALAHVRDGGQSLHSALFRGSAASGASGLEKQAEALRVKNAVYCAVIFSEFLKELAALAQEHAVALPFPPSQGTEE", "length": 1124 }, "evidence": [ { "id": "FB:FBgn0025681", "url": "https://alliancegenome.org/gene/FB:FBgn0025681#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q05DH4-1", "protein_name": "FHF complex subunit HOOK-interacting protein 1A", "gene_name": "FHIP1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMSSVSTESKLQQAVSLQGVDPETCMIVFKNHWAQVVKILEKHDPLKNTQAKYGSIPPDEASAVQNYVEHMLFLLIEEQAKDAAMGPILEFVVSENIMEKLFLWSLRREFTDETKIEQLKMYEMLVTQSHQPLLHHKPILKPLMMLLSSCSGTTTPTVEEKLVVLLNQLCSILAKDPSILELFFHTSEDQGAANFLIFSLLIPFIHREGSVGQQARDALLFIMSLSAENTMVAHHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEEWHCLLKDDWLLLPSLVQFMNSLEFCNAVIQVAHPLIRNQLVNYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHQHENVHILDTLTSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLVLRYLIPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCSSGITLTLGNQERDYILWSKCMHDTSGPVERPFPEAFSESACIVEYGKALDISYLQYLWEAHTNILRCMRDCRVWSALYDGDSPDPEMFLQSLTEEGSVSSACPVFGLPQQLPRKTGPQLAPRKDKSQTELEWDDSYDTGISSGADVGSPGPYDDLEVSGPPAPIDPPKHIQEMKKNALLLFKGSYIEESDFQDDVMVYRLCAEKDSEDMKDSQEEAARPPAEAQAEVQSVPINNGPLLSTQPETDSEEEWNRDNSDPFHSEPKEPKQEREPEAAPESNSELASPAPEAEHSSNLTAAHPESEELIAQYDQIIKELDSGAEGLMEQNYPTPDPLLLTKEEEGKEESKGEKEKEGKKELEDEEDDFDSFIAEMPAVETVPSPFVGRDEAAFASRHPVRTQSTPFTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMTPAALTKDPIQEASRTGSGKNLLDGPPRVLQPFLTHRTKVAEAPPNLPLPVRNPMLAAALFPEFLKELAALAQEHSILCYKILGDFEDSCC", "length": 1040 }, "evidence": [ { "id": "HGNC:34237", "url": "https://alliancegenome.org/gene/HGNC:34237#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-132#orthology", "database": "AGR" }, { "id": "RGD:1565007", "url": "https://alliancegenome.org/gene/RGD:1565007#orthology", "database": "AGR" }, { "id": "MGI:2444746", "url": "https://alliancegenome.org/gene/MGI:2444746#orthology", "database": "AGR" }, { "id": "FB:FBgn0025681", "url": "https://alliancegenome.org/gene/FB:FBgn0025681#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3U2I3-1", "protein_name": "FHF complex subunit HOOK-interacting protein 1B", "gene_name": "Fhip1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKMNWLSRLASRVPGHRVPQGASLQTPVMADPETCLMVFKNHWSQVVRILERQGPRAATGGADDLSAVRNHTYQMLTLLAEDRAVPSAPSGPGPLLEFALREDLLSRVLTWQLQWDEFGDGVEERRAEQLKLFEMLVSEARQPLLRHGPVREALLALLDACGRPVPSSPALDEGLVLLLSQLCVCVAREPSLLEFFLQPPPEPGAAPRLLLFSRLVPFVHREGTLGQQARDALLLLMALSDGSPTVGRYIADHSYFCPVLATGLSALYSSLPRKIEVPGDDWHCLRREDWIGVPALALFMSSLEFCNAVIQVAHPLVQKQLVDYIHNGFLVPVMGPALHKTSVEEMIASTAYLELFLRSISEPALLRTFLRFLLLHRHDTHTILDTLVARIGSNSRLCMVSLSLFRTLLNLSCEDVLLQLVLRYLVPCNHVMLSQKPAVRDVDLYGRAADKFLSLIPRCCRHHAPSPPRPEHASWARGPGSPSVDSSSVVTVPRPSTPSRLALFLRQQSLGGSESPGPVPRSPGLTASPTSSPSRRPSPAEEPGELEDNYLEYLREARRGVDRCVRACRTWSAPYDGERPPPEPNPLGSRTKKRSLLPEEDRDNVREGEEENLGSRGLAVGVGDTPGYLLPPQLNGVPGPWPEGAKKVRLVPRLVPQEGVRELLEGTSEDMAGLESFGQELQELEVALSNGGAGSEPPLEPPLPPEEEEAYESFTCPPEPPGPFLSSPLRTLHQLPSQPFTGPFMAVLFAKLENMLQNSVYVNFLLTGLVAQLACHPQPLLRSFLLNTNMVFQPSVKSLLQVLGSVKNKIESFAASQEDFPALLSKAKKYLIARGKLDWAEGPTAGPAPRRSDSLVRSRRPSLGELLLRHAHSPTRARQAVQVLQPGRDGTGLGLGGGSPGASTPVLLPRGGASERQGEALRVKNAVYCAVIFPEFLKELAAISQAHAVTSPFLLDTSEEVSLPPISGFGPLNP", "length": 975 }, "evidence": [ { "id": "FB:FBgn0025681", "url": "https://alliancegenome.org/gene/FB:FBgn0025681#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q505K2-1", "protein_name": "FHF complex subunit HOOK-interacting protein 1A", "gene_name": "Fhip1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMSSVSTESKLQQAVSLKGVDPETCMIVFKNHWAQVVKILEKHDPLKNTQAKYGSIPPDEASAVQNYVEHMLFLLIEEQAKDAAMGPILEFVVCENIMEKLFLWSLRREFTDETKLEQLKMYEMLVTQSYQPLLHHKPILKPLMMLLSSCSGTATPAVEGKLVVLLNQLCSILAKDPSILELFFHTSEDQGAANFLIFSLLIPFIHREGTVGQQARDALLFIMSLSAENSMVANHIVENTYFCPVLATGLSGLYSSLPTKLEEKGEDWHCILKDDWLLLPALVQFMNSLEFCNAVIQVAHPLIRTQLVSYIYNGFLVPVLAPALHKVTVEEVMTTTAYLDLFLRSISEPALLEIFLRFILLHRHENVHILDTLTSRINTPFRLCVVSLALFRTLIGLHCEDVMLQLVLRYLVPCNHMMLSQRWAVKERDCYSVSAAKLLALTPVCCASGITLTLGNQERDYILWSKCMHDGSGSEEQLLPETPCSPSSPSPPPPPAPAACIVEYGKALDISYLQYLWEAHTNILHCMRDCRVWSALYDGDSPDPETFLQSLSEESRENSGHPEARLPQQSVRTSGQTKDKSQSELEWDDSYDTGISSGADVGSPGPDDEVETPAPPAPIDPPKHIQEMKKNAILLFKGSYIEESDFQDDVMVYRLCAEKDTEDTTEPQKDTSEPQGDTLEPLEDTSEQQEDTSEQLEDTSELQEDTAEPQGDTADPTAEAQPKLQPEAQSLPTSNGPLSSPDPETESQPSRESSDLCQNTFSEAKPENEPGVALALDSELIATTFEAEPQSELAVVSTESEDFIAQYDQIIQELDSGTEGLTEQSIPISEPSLLTQQEERREECKEEEDDDFDSLMAATPAVEAGSSPFGVGEDTAFSSRHPVRTQSTPFTGPFISVVLSKLENMLENSLHVNLLLIGIITQLASYPQPLLRSFLLNTNMVFQPSVRSLYQVLASVKNKIEQFASVERDFPGLLIQAQQYLLFRVDMSDMAPAALTKDPIQEISRPESDKTLLDGPPRVLQPFLGNRAKVTRAPPNLPLPVKNTMLAAALFPEFLKELAALAQEHSILCYKILGDFEDSCC", "length": 1081 }, "evidence": [ { "id": "HGNC:34237", "url": "https://alliancegenome.org/gene/HGNC:34237#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-132#orthology", "database": "AGR" }, { "id": "RGD:1565007", "url": "https://alliancegenome.org/gene/RGD:1565007#orthology", "database": "AGR" }, { "id": "MGI:2444746", "url": "https://alliancegenome.org/gene/MGI:2444746#orthology", "database": "AGR" }, { "id": "FB:FBgn0025681", "url": "https://alliancegenome.org/gene/FB:FBgn0025681#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66H54-1", "protein_name": "FHF complex subunit HOOK-interacting protein 1B", "gene_name": "Fhip1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKMNWLSRLASRVPGHRVPQGASLQTPVMADPETCLMVFKNHWSQVVRILERQGSRAAAGGADDLSAVRNHTYQMLTLLAEDRAVPSAPSGPGPLLEFALREDLLSRVLTWQLQWDEFGDGVEERRAEQLKLFEMLVSEARQPLLRHGPVREALLALLDACGRPVPSSPALDEGLVLLLSQLCVCVAREPSLLEFFLQPPPEPGAAPRLLLFSRLVPFVHREGTLGQQARDALLLLMALSDGSPTVGRYIADHSYFCPVLATGLSALYSSLPRKIEVPGDDWHCLRREDWIGVPALALFMSSLEFCNAVIQVAHPLVQKQLVDYIHNGFLVPVMGPALHKTSVEEMIASTAYLELFLRSISEPALLRTFLRFLLLHRHDTHTILDTLVARIGSNSRLCMVSLSLFRTLLNLSCEDVLLQLVLRYLVPCNHVMLSQKPAVRDVDLYGRAADKFLSLIPRCCRHHAPSPPRPEHASWARGGPSREPGRREDITGPGSPSVDSSSVVTVPRPSTPSRLALFLRQQSLGGSESPGPAPRSPGLTASPTSSPGRRPSPAEEPGPFMAVLFAKLENMLQNSVYVNFLLTGLVAQLACHPQPLLRSFLLNTNMVFQPSVKSLLQVLGSVKNKIESFAASQEDFPALLSKAKKYLIARGKLDWAEGPTAGPTPRRSDSLVRSRRPSLGELLLRHAHSPTRARQAVQVLQPGRDGTGLGLGGGSPGASTPVLLPRGGASERQGEALRVKNAVYCAVIFPEFLKELAAISQAHAVTSPFLLDTSEEVSVPPISGFGPLNP", "length": 791 }, "evidence": [ { "id": "FB:FBgn0025681", "url": "https://alliancegenome.org/gene/FB:FBgn0025681#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N612-1", "protein_name": "FHF complex subunit HOOK-interacting protein 1B", "gene_name": "FHIP1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERMNWLSRLASRGPGHRIPQGANLQTPVMADPETCLMVFKNHWSQVVRILERQGPRAAPGGADDLSAVRNHTYQMLTLLAEDRAVPSAPTGPGPLLEFALHEDLLTRVLTWQLQWDELGDGVEERRAEQLKLFEMLVSEARQPLLRHGPVREALLTLLDACGRPVPSSPALDEGLVLLLSQLCVCVAQEPSLLEFFLQPPPEPGAAPRLLLFSRLVPFVHREGTLGQQARDALLLLMALSAGSPTVGRYIADHSYFCPVLATGLSALYSSLPRKIEVPGDDWHCLRREDWLGVPALALFMSSLEFCNAVIQVAHPLVQKQLVDYIHNGFLVPVMGPALHKTSVEEMIASTAYLELFLRSISEPALLRTFLRFLLLHRHDTHTILDTLVARIGSNSRLCMVSLSLFRTLLNLSCEDVLLQLVLRYLVPCNHVMLSQKPAVRDVDLYGRAADKFLSLIPRCCRHHAPSPPRPEHASWARGPGSPSVDSSSVTTVPRPSTPSRLALFLRQQSLGGSESPGPAPCSPGLSASPASSPGRRPTPAEEPGELEDNYLEYLREARRGVDRCVRACRTWSAPYDGERPSPEPSPFGSRTKKRSLLPEEDRNNVGEGEEEELGRRGRAGGAGEGPGHLPPPQLNGVPGSWPEGAKKVRLVPKEGAGELLEGISEGMAGLEGFGQELRELEVALSNGGTGSESPLEPPLPLEEEEAYESFTCPPEPPGPFLSSPLRTLNQLPSQPFTGPFMAVLFAKLENMLQNSVYVNFLLTGLVAQLACHPQPLLRSFLLNTNMVFQPSVKSLLQVLGSVKNKIENFAASQEDFPALLSKAKKYLIARGKLDWAEGPAAGPAPRRSDPLVKSRRPSLGELLLRHAHSPTRARQAAQLVLQPGRDGAGLGLSGGSPGASTPVLLTRGGAPERQGEALRVKNAVYCAVIFPEFLKELAAISQAHAVTSPFLLETSEEGSGPLISGCGPLNP", "length": 972 }, "evidence": [ { "id": "FB:FBgn0025681", "url": "https://alliancegenome.org/gene/FB:FBgn0025681#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VQK0-1", "protein_name": "FHIP family protein CG3558", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWLRQSSGGGVASVGHVGPLRQRPIDAATDCDPRACYDSFCKHWQQAFEIIQHSAPPSHDDVLGVVSHLDYMVTLLLVELHHCNKVSLPAAEASGPPAAPCLEFLLSENLLDKLYEWACTTGRYANAVRLEQLKLYELLVSHSRHQLLCHEPFLRPLLKILASSQGEIFPPDLEKRLVILLNQLCVVLMQNVHLLDLFFFSAQTQVQEQILNGNVAPPKSGTTTNFIIFSLLIPYVHREGSLGHQARDALLLCMALSQKNSNIGTYIAQYSSICPLLVTGLGGLYSRLPNSIEISSIDWHRITPDDVTEIPELTLFMNALEFCNAVVQVAHEMIKQQLLDFMYQGFIVPVLGPAILQTNIDSQISAMSYLDLILRSITEPGLLRAFVRFLLDTEKFDGERILDALVERLNSPDANLCMVTMALFDTLLGLHCEDLMLELLLKFMLPGKHVPISHRHKINKIDPYLNSSEFFLELSPDVMKRARDLARPKSVHEPVVSELTPLPSLPSPVMSKTIGANWNYYGVHTGDSLYANIQAYLFEAHWRIAQCQKDCLKWANSYRYQKWPRHGQGRVHAHALELARQFFSEFGGGPIAANETGEKQLDSLQSIGESSGYESFKWRPADEESEATDTTVATTASEADMDHNSSSLSSVLGASGKRESWRTSNSNRNELILTDLDFSEDLFAQGTVSLGPFLNAIWGKLQTFTSNSLYVNLHLTGLITRLAWYPLPLIHSLLLRSDIAITSDTPSFHQVLRILKQQIDAELPVTEDSLEIIDVARSSLIDREFRLANARKGNEGSPMHHSQQQQMVTNSGQQQGQLRSAYATLSAATPVQATPTSAYDPFKRSDNKRRSISKSITSMFSRKSASTSTAPPNGSSASSGLSQIYAFFTGAASNLVGNNASNDGRGISQAQTSAGTCETSLSTQPPAGASRTGANATSTAASGSNSSIAGSTLTLSAQSNTTTHSASTLHGLDGGPSTGGFNSEPASLDSVASMGIIASTSGTERSRDLALCAVLMDEWLKELAAIAQEQSVVLVTEQGSL", "length": 1041 }, "evidence": [ { "id": "HGNC:34237", "url": "https://alliancegenome.org/gene/HGNC:34237#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-132", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-132#orthology", "database": "AGR" }, { "id": "RGD:1565007", "url": "https://alliancegenome.org/gene/RGD:1565007#orthology", "database": "AGR" }, { "id": "MGI:2444746", "url": "https://alliancegenome.org/gene/MGI:2444746#orthology", "database": "AGR" }, { "id": "FB:FBgn0025681", "url": "https://alliancegenome.org/gene/FB:FBgn0025681#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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The reference sequence was derived from JBMGRA010000004.1. On Jun 26, 2024 this sequence version replaced NP_001004629.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001004629", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001004629" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUV1", "url": "https://www.uniprot.org/uniprotkb/A5WUV1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ms4a17a.5", "url": "https://www.uniprot.org/uniprotkb/A5WUV1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040912-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040912-55", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ZFIN:ZDB-GENE-131126-22", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131126-22", "database": "AGR", "categories": [ "Protein Classification" ] 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CANONICAL=A5WUV1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Phylogenetic analysis of the MS4A and TMEM176 gene families.", "journal": "PLoS ONE", "date": "2010", "authors": "Zuccolo Jonathan, Bau Jeremy, Childs Sarah J, Goss Greg G, Sensen Christoph W, Deans Julie P", "evidence": [ { "database": "UniProtKB", "id": "A5WUV1", "url": "https://www.uniprot.org/uniprotkb/A5WUV1" } ], "reference": [ { "type": "PubMed", "id": "20186339", "url": "https://glygen.org/publication/PubMed/20186339" } ] }, { "title": "Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.", "journal": "J. 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familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] }, { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "GC", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] }, { "disease_id": "DOID:10591", "recommended_name": { "id": "DOID:10591", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10591", "name": "pre-eclampsia", "description": "A hypertension occurring during pregnancy characterized by large amounts of protein in the urine (proteinuria) and edema, usually by the last trimester of pregnancy." }, "synonyms": [ { "id": "DOID:10591", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10591", "name": "gestational hypertension", "description": "" }, { "id": "DOID:10591", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10591", "name": "hypertension induced by pregnancy", "description": "" }, { "id": "DOID:10591", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10591", "name": "pre-eclamptic toxaemia", "description": "" }, { "id": "DOID:10591", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10591", "name": "preeclampsia", "description": "" }, { "id": "DOID:10591", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10591", "name": "preeclampsia/eclampsia", "description": "" }, { "id": "DOID:10591", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10591", "name": "pregnancy associated hypertension", "description": "" }, { "id": "DOID:10591", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10591", "name": "pregnancy toxemia", "description": "" }, { "id": "DOID:10591", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10591", "name": "proteinuric hypertension of pregnancy", "description": "" }, { "id": "DOID:10591", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10591", "name": "toxaemia of pregnancy", "description": "" }, { "id": "MONDO:0012264", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012264", "name": "preeclampsia/eclampsia 2", "description": "" }, { "id": "MONDO:0012264", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012264", "name": "PEE2", "description": "" }, { "id": "MONDO:0012264", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012264", "name": "PREECLAMPSIA/eclampsia 2", "description": "" }, { "id": "MONDO:0012265", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012265", "name": "preeclampsia/eclampsia 3", "description": "" }, { "id": "MONDO:0012265", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012265", "name": "PEE3", "description": "" }, { "id": "MONDO:0012265", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012265", "name": "PREECLAMPSIA/eclampsia 3", "description": "" }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "preeclampsia/eclampsia 4", "description": "Any preeclampsia in which the cause of the disease is a mutation in the STOX1 gene." }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "Preeclampsia/eclampsia type 4", "description": "" }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "STOX1 preeclampsia", "description": "" }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "preeclampsia caused by mutation in STOX1", "description": "" }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "preeclampsia/eclampsia 4", "description": "" }, { "id": "MONDO:0012266", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012266", "name": "PEE4", "description": "" }, { "id": "MONDO:0100467", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100467", "name": "preeclampsia/eclampsia 1", "description": "" }, { "id": "MONDO:0100467", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100467", "name": "toxaemia of pregnancy", "description": "" }, { "id": "MONDO:0100467", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100467", "name": "toxemia of pregnancy", "description": "" }, { "id": "MONDO:0100467", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100467", "name": "PEE1", "description": "" }, { "id": "MONDO:0100467", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100467", "name": "PREECLAMPSIA/eclampsia 1", "description": "" }, { "id": "MONDO:0100467", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100467", "name": "PREG1", "description": "" }, { "id": "MIM:609404", "resource": "MIM", "url": "https://www.omim.org/entry/609404", "name": "Pre-eclampsia/eclampsia 4", "description": "Pre-eclampsia/eclampsia 4" } ], "unlinked_id_list": [], "evidence": [ { "id": "10591", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10591" } ] }, { "disease_id": "DOID:1324", "recommended_name": { "id": "DOID:1324", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1324", "name": "lung cancer", "description": "A respiratory system cancer that is located_in the lung." }, "synonyms": [ { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "A malignant neoplasm involving the lung." }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "adenocarcinoma of lung, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "cancer of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, resistance to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung neoplasm", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumor", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant lung tumour", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant neoplasm of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumor of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "malignant tumour of the lung", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, response to tyrosine kinase inhibitor in, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, somatic", "description": "" }, { "id": "MONDO:0008903", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008903", "name": "nonsmall cell lung cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "LNCR1", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility", "description": "" }, { "id": "MONDO:0012159", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012159", "name": "lung cancer susceptibility 1", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "LNCR3", "description": "" }, { "id": "MONDO:0012942", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012942", "name": "lung cancer susceptibility 3", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "LNCR4", "description": "" }, { "id": "MONDO:0012955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012955", "name": "lung cancer susceptibility 4", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "LNCR5", "description": "" }, { "id": "MONDO:0013631", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013631", "name": "lung cancer susceptibility 5", "description": "" }, { "id": "MIM:211980", "resource": "MIM", "url": "https://www.omim.org/entry/211980", "name": "Lung cancer", "description": "Lung cancer" } ], "unlinked_id_list": [ "DOID:4765" ], "evidence": [ { "id": "1324", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1324" } ] }, { "disease_id": "DOID:1936", "recommended_name": { "id": "DOID:1936", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1936", "name": "atherosclerosis", "description": "An arteriosclerotic cardiovascular disease that is characterized by the build-up of fatty material and calcium deposition in the arterial wall resulting in partial or complete occlusion of the arterial lumen. Disease is located within the tunica intima of large and small arteries." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "1936", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1936" } ] }, { "disease_id": "DOID:3393", "recommended_name": { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles." }, "synonyms": [ { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "CHD", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Coronary disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary arteriosclerosis", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary heart disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Ischemic Heart Disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "myocardial ischemia", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, type 3", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the CX3CR1 gene." }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "CX3CR1 coronary artery disease", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease caused by mutation in CX3CR1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease, resistance to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, type 2", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, type 4", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the MEF2A gene." }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "MEF2A coronary artery disease", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease caused by mutation in MEF2A", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, type 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "ADCAD1", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the LRP6 gene." }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "LRP6 coronary artery disease", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease caused by mutation in LRP6", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant type 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant, 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "ADCAD2", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "CHDS8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "CHDS9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the KHDC3L gene." }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "KHDC3L complete hydatidiform mole", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "complete hydatidiform mole caused by mutation in KHDC3L", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform Mole, recurrent, type 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "HYDM2", "description": "" }, { "id": "MIM:608320", "resource": "MIM", "url": "https://www.omim.org/entry/608320", "name": "Coronary artery disease, autosomal dominant, 1", "description": "Coronary artery disease, autosomal dominant, 1" }, { "id": "MIM:610947", "resource": "MIM", "url": "https://www.omim.org/entry/610947", "name": "Coronary artery disease, autosomal dominant, 2", "description": "Coronary artery disease, autosomal dominant, 2" }, { "id": "MIM:614293", "resource": "MIM", "url": "https://www.omim.org/entry/614293", "name": "Hydatidiform mole, recurrent, 2", "description": "Hydatidiform mole, recurrent, 2" } ], "unlinked_id_list": [ "DOID:11840" ], "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ] }, { "disease_id": "DOID:3748", "recommended_name": { "id": "DOID:3748", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3748", "name": "esophagus squamous cell carcinoma", "description": "An esophageal carcinoma that derives_from epithelial squamous cells located_in the esophagus." }, "synonyms": [ { "id": "DOID:3748", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3748", "name": "SCC of esophagus", "description": "" }, { "id": "DOID:3748", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3748", "name": "SCC of oesophagus", "description": "" }, { "id": "DOID:3748", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3748", "name": "oesophagus squamous cell carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3748", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3748" } ] }, { "disease_id": "DOID:3908", "recommended_name": { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma." }, "synonyms": [ { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "NSCLC", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "Non-small cell lung cancer", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "non-small cell lung carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:684", "recommended_name": { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver." }, "synonyms": [ { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "Hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MIM:114550", "resource": "MIM", "url": "https://www.omim.org/entry/114550", "name": "Hepatocellular carcinoma", "description": "Hepatocellular carcinoma" } ], "unlinked_id_list": [], "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ] }, { "disease_id": "DOID:7693", "recommended_name": { "id": "DOID:7693", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7693", "name": "abdominal aortic aneurysm", "description": "An aortic aneurysm that is located_in the abdominal aorta." }, "synonyms": [ { "id": "DOID:7693", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:7693", "name": "AORTIC ANEURYSM, FAMILIAL ABDOMINAL 1", "description": "" }, { "id": "MONDO:0012343", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012343", "name": "aortic aneurysm, familial abdominal, 2", "description": "" }, { "id": "MONDO:0012343", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012343", "name": "AAA2", "description": "" }, { "id": "MONDO:0012343", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012343", "name": "aortic aneurysm, familial abdominal 2", "description": "" }, { "id": "MONDO:0012343", "resource": "MONDO", "url": 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"categories": [ "Protein" ] }, { "id": "A5PF31", "url": "https://www.uniprot.org/uniprotkb/A5PF31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PF31-1", "url": "https://www.uniprot.org/uniprotkb/A5PF31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RAN5", "url": "https://www.uniprot.org/uniprotkb/F1RAN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1RAN5-1", "url": "https://www.uniprot.org/uniprotkb/F1RAN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-2449", "url": "https://zfin.org/ZDB-GENE-030131-2449", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSGVTRKGSGRPGYYYRLLGRTRLQRQRSRSRSRSRVTNNKDSPPERTGRRRSIPGSAPDKVPPTMEPTAAAAATPFRVTGFLSRRLKGSIKRTKSQPKLDRNSSFRHILPGFRPVDNERSHLMPRLKESRSHESLLSPTSAVEALDLSMEEEVLIKPVHSSILGQDYCFEVSTSTGSKCFSCRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKKYFCELCLDDSLYARTTCKMKTDNVFWGEHFEFNNLPAVQSITVHVYRDSDKKKKKDKNNYVGLVSIPVVTVTSRQLVEKWYPVSQPNPGKGKAAGPMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSSSDLPEHQSNLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGRPDISERLISASLFLRFLCPAIMSPSLFNLTQEYPDDRTARTLTLIAKVTQNLANFTKFGNKEEYMSFMNQFLEQEWTNMQRFLLEISNPETISNTAGFEGYIDLGRELSTLHSLLAEVLSQMDQSAASKLGPLPRILRDVHGALTNPTNVQMSVPSDRVPSPPVPGCSISTGIQKMAIDSDLPGPVDFTRLPSPTPENKDLFFVTRSSGLQGSPTRSSSYSEANEPELGLANGGKSLSMVDLQEAARALEPISIPAGITSEGMGEGAMVPWNARTPQGNIAGGPTLHRPVQSPTTPGAEGAPGRPTQLLAPLSFQNPVYQMAAGLPVSARGNASGDSGSECHSSVSSHSNNEECLGGTKTTFLTQGASVGEEFARRSGDFSRRQLSLTDPQHGNQPTVPRQSSAGPQRRIDQPPPPTQTAPRGRTPPNLLNSGPYPRPLNNTMMSSSPDWPGSGARLRQQSSSSKGDSPETKHRAPHKQAPSPVNPSALDRTAAWLMNVPYIEQEPETELCRDEHTQAEKYQAEISMLQDRLRMSVQRLEEYEARLKGQEEQAQKMLLEYQARLDESEERLRRQQEDKDLQMKGIISRLMSVEEELKKDHADMQAVVDSKQKIIDAQEKRIASLDAANARLMSALSQLKERYSMQTRNGISPTNPTKLQITENGEFRNSSNC", "length": 1180, "header": "tr|A5PF31-1|A5PF31_DANRE Isoform 1 of DAB2 interacting protein b isoform X1 OS=Danio rerio OX=7955 GN=dab2ipb PE=4 SV=1 CANONICAL=A5PF31-1" }, "isoforms": [ { "isoform_ac": "A0A0R4INY5-1", "url": "https://www.uniprot.org/uniprotkb/A5PF31/entry#A0A0R4INY5-1", "sequence": { "sequence": "MESETSPESEGQSDSPPERTGRRRSIPGSAPDKVPPTMEPTAAAAATPFRVTGFLSRRLKGSIKRTKSQPKLDRNSSFRHILPGFRPVDNERSHLMPRLKESRSHESLLSPTSAVEALDLSMEEEVLIKPVHSSILGQDYCFEVSTSTGSKCFSCRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKKYFCELCLDDSLYARTTCKMKTDNVFWGEHFEFNNLPAVQSITVHVYRDSDKKKKKDKNNYVGLVSIPVVTVTSRQLVEKWYPVSQPNPGKGKAAGPMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSSSDLPEHQSNLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGRPDISERLISASLFLRFLCPAIMSPSLFNLTQEYPDDRTARTLTLIAKVTQNLANFTKFGNKEEYMSFMNQFLEQEWTNMQRFLLEISNPETISNTAGFEGYIDLGRELSTLHSLLAEVLSQMDQSAASKLGPLPRILRDVHGALTNPTNVQMSVPSDRVPSPPVPGCSISTGIQKMAIDSDLPGPVDFTRLPSPTPENKDLFFVTRSSGLQGSPTRSSSYSEANEPELGLANGGKSLSMVDLQEAARALEPISIPAGITSEGMGEGAMVPWNARTPQGNIAGGPTLHRPVQSPTTPGAEGAPGRPTQLLAPLSFQNPVYQMAAGLPVSARGNASGDSGSECHSSVSSHSNNEECLGGTKTTFLTQGASVGEEFARRSGDFSRRQLSLTDPQHGNQPTVPRQSSAGPQRRIDQPPPPTQTAPRGRTPPNLLNSGPYPRPLNNTMMSSSPDWPGSGARLRQQSSSSKGDSPETKHRAPHKQAPSPVNPSALDRTAAWLMNVPYIEQEPETELCRDEHTQAEKYQAEISMLQDRLRMSVQRLEEYEARLKGQEEQAQKMLLEYQARLDESEERLRRQQEDKDLQMKGIISRLMSVEEELKKDHADMQAVVDSKQKIIDAQEKRIASLDAANARLMSALSQLKERYSMQTRNGISPTNPTKLQITENGEFRNSSNC", "length": 1152, "header": "tr|A0A0R4INY5-1|A5PF31_DANRE Computationally mapped isoform of DAB2 interacting protein b isoform X1 OS=Danio rerio OX=7955 GN=dab2ipb PE=4 SV=1 CANONICAL=A5PF31-1" }, "locus": {} }, { "isoform_ac": "A0AB32TQX4-1", "url": "https://www.uniprot.org/uniprotkb/A5PF31/entry#A0AB32TQX4-1", "sequence": { "sequence": "MSTLDFCGAKWIFVEFLCPMPRLMSHLMPRLKESRSHESLLSPTSAVEALDLSMEEEVLIKPVHSSILGQDYCFEVSTSTGSKCFSCRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKKYFCELCLDDSLYARTTCKMKTDNVFWGEHFEFNNLPAVQSITVHVYRDSDKKKKKDKNNYVGLVSIPVVTVTSRQLVEKWYPVSQPNPGKGKAAGPMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSSSDLPEHQSNLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGRPDISERLISASLFLRFLCPAIMSPSLFNLTQEYPDDRTARTLTLIAKVTQNLANFTKFGNKEEYMSFMNQFLEQEWTNMQRFLLEISNPETISNTAGFEGYIDLGRELSTLHSLLAEVLSQMDQSAASKLGPLPRILRDVHGALTNPTNVQMSVPSDRVPSPPVPGCSISTGIQKMAIDSDLPGPVDFTRLPSPTPENKDLFFVTRSSGLQGSPTRSSSYSEANEPELGLANGGKSLSMVDLQEAARALEPISIPAGITSEGMGEGAMVPWNARTPQGNIAGGPTLHRPVQSPTTPGAEGAPGRPTQLLAPLSFQNPVYQMAAGLPVSARGNASGDSGSECHSSVSSHSNNEECLGGTKTTFLTQGASVGEEFARRSGDFSRRQLSLTDPQHGNQPTVPRQSSAGPQRRIDQPPPPTQTAPRGRTPPNLLNSGPYPRPLNNTMMSSSPDWPGSGARLRQQSSSSKGDSPETKHRAPHKQAPSPVNPSALDRTAAWLMNVPYIEQEPETELCRDEHTQAEKYQAEISMLQDRLRMSVQRLEEYEARLKGQEEQAQKMLLEYQARLDESEERLRRQQEDKDLQMKGIISRLMSVEEELKKDHADMQAVVDSKQKIIDAQEKRIASLDAANARLMSALSQLKERYSMQTRNGISPTNPTKLQITENGEFRNSSNC", "length": 1084, "header": "tr|A0AB32TQX4-1|A5PF31_DANRE Computationally mapped isoform of DAB2 interacting protein b isoform X1 OS=Danio rerio OX=7955 GN=dab2ipb PE=4 SV=1 CANONICAL=A5PF31-1" }, "locus": {} }, { "isoform_ac": "A5PF29-1", "url": "https://www.uniprot.org/uniprotkb/A5PF31/entry#A5PF29-1", "sequence": { "sequence": "MEPTAAAAATPFRVTGFLSRRLKGSIKRTKSQPKLDRNSSFRHILPGFRPVDNERSHLMPRLKESRSHESLLSPTSAVEALDLSMEEEVLIKPVHSSILGQDYCFEVSTSTGSKCFSCRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKKYFCELCLDDSLYARTTCKMKTDNVFWGEHFEFNNLPAVQSITVHVYRDSDKKKKKDKNNYVGLVSIPVVTVTSRQLVEKWYPVSQPNPGKGKAAGPMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSSSDLPEHQSNLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGRPDISERLISASLFLRFLCPAIMSPSLFNLTQEYPDDRTARTLTLIAKVTQNLANFTKFGNKEEYMSFMNQFLEQEWTNMQRFLLEISNPETISNTAGFEGYIDLGRELSTLHSLLAEVLSQMDQSAASKLGPLPRILRDVHGALTNPTNVQMSVPSDRVPSPPVPGCSISTGIQKMAIDSDLPGPVDFTRLPSPTPENKDLFFVTRSSGLQGSPTRSSSYSEANEPELGLANGGKSLSMVDLQEAARALEPISIPAGITSEGMGEGAMVPWNARTPQGNIAGGPTLHRPVQSPTTPGAEGAPGRPTQLLAPLSFQNPVYQMAAGLPVSARGNASGDSGSECHSSVSSHSNNEECLGGTKTTFLTQGASVGEEFARRSGDFSRRQLSLTDPQHGNQPTVPRQSSAGPQRRIDQPPPPTQTAPRGRTPPNLLNSGPYPRPLNNTMMSSSPDWPGSGARLRQQSSSSKGDSPETKHRAPHKQAPSPVNPSALDRTAAWLMNVPYIEQEPETELCRDEHTQAEKYQAEISMLQDRLRMSVQRLEEYEARLKGQEEQAQKMLLEYQARLDESEERLRRQQEDKDLQMKGIISRLMSVEEELKKDHADMQAVVDSKQKIIDAQEKRIASLDAANARLMSALSQLKERYSMQTRNGISPTNPTKLQITENGEFRNSSNC", "length": 1115, "header": "tr|A5PF29-1|A5PF29_DANRE Computationally mapped isoform of DAB2 interacting protein b isoform X3 OS=Danio rerio OX=7955 GN=dab2ipb PE=4 SV=1 CANONICAL=A5PF31-1" }, "locus": {} }, { "isoform_ac": "A5PF30-1", "url": "https://www.uniprot.org/uniprotkb/A5PF31/entry#A5PF30-1", "sequence": { "sequence": "MPRLKESRSHESLLSPTSAVEALDLSMEEEVLIKPVHSSILGQDYCFEVSTSTGSKCFSCRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKKYFCELCLDDSLYARTTCKMKTDNVFWGEHFEFNNLPAVQSITVHVYRDSDKKKKKDKNNYVGLVSIPVVTVTSRQLVEKWYPVSQPNPGKGKAAGPMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSSSDLPEHQSNLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGRPDISERLISASLFLRFLCPAIMSPSLFNLTQEYPDDRTARTLTLIAKVTQNLANFTKFGNKEEYMSFMNQFLEQEWTNMQRFLLEISNPETISNTAGFEGYIDLGRELSTLHSLLAEVLSQMDQSAASKLGPLPRILRDVHGALTNPTNVQMSVPSDRVPSPPVPGCSISTGIQKMAIDSDLPGPVDFTRLPSPTPENKDLFFVTRSSGLQGSPTRSSSYSEANEPELGLANGGKSLSMVDLQEAARALEPISIPAGITSEGMGEGAMVPWNARTPQGNIAGGPTLHRPVQSPTTPGAEGAPGRPTQLLAPLSFQNPVYQMAAGLPVSARGNASGDSGSECHSSVSSHSNNEECLGGTKTTFLTQGASVGEEFARRSGDFSRRQLSLTDPQHGNQPTVPRQSSAGPQRRIDQPPPPTQTAPRGRTPPNLLNSGPYPRPLNNTMMSSSPDWPGSGARLRQQSSSSKGDSPETKHRAPHKQAPSPVNPSALDRTAAWLMNVPYIEQEPETELCRDEHTQAEKYQAEISMLQDRLRMSVQRLEEYEARLKGQEEQAQKMLLEYQARLDESEERLRRQQEDKDLQMKGIISRLMSVEEELKKDHADMQAVVDSKQKIIDAQEKRIASLDAANARLMSALSQLKERYSMQTRNGISPTNPTKLQITENGEFRNSSNC", "length": 1057, "header": "tr|A5PF30-1|A5PF30_DANRE Computationally mapped isoform of DAB2 interacting protein b isoform X5 OS=Danio rerio OX=7955 GN=dab2ipb PE=4 SV=1 CANONICAL=A5PF31-1" }, "locus": {} }, { "isoform_ac": "A5PF31-1", "url": "https://www.uniprot.org/uniprotkb/A5PF31/entry#A5PF31-1", "sequence": { "sequence": "MSGVTRKGSGRPGYYYRLLGRTRLQRQRSRSRSRSRVTNNKDSPPERTGRRRSIPGSAPDKVPPTMEPTAAAAATPFRVTGFLSRRLKGSIKRTKSQPKLDRNSSFRHILPGFRPVDNERSHLMPRLKESRSHESLLSPTSAVEALDLSMEEEVLIKPVHSSILGQDYCFEVSTSTGSKCFSCRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKKYFCELCLDDSLYARTTCKMKTDNVFWGEHFEFNNLPAVQSITVHVYRDSDKKKKKDKNNYVGLVSIPVVTVTSRQLVEKWYPVSQPNPGKGKAAGPMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSSSDLPEHQSNLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGRPDISERLISASLFLRFLCPAIMSPSLFNLTQEYPDDRTARTLTLIAKVTQNLANFTKFGNKEEYMSFMNQFLEQEWTNMQRFLLEISNPETISNTAGFEGYIDLGRELSTLHSLLAEVLSQMDQSAASKLGPLPRILRDVHGALTNPTNVQMSVPSDRVPSPPVPGCSISTGIQKMAIDSDLPGPVDFTRLPSPTPENKDLFFVTRSSGLQGSPTRSSSYSEANEPELGLANGGKSLSMVDLQEAARALEPISIPAGITSEGMGEGAMVPWNARTPQGNIAGGPTLHRPVQSPTTPGAEGAPGRPTQLLAPLSFQNPVYQMAAGLPVSARGNASGDSGSECHSSVSSHSNNEECLGGTKTTFLTQGASVGEEFARRSGDFSRRQLSLTDPQHGNQPTVPRQSSAGPQRRIDQPPPPTQTAPRGRTPPNLLNSGPYPRPLNNTMMSSSPDWPGSGARLRQQSSSSKGDSPETKHRAPHKQAPSPVNPSALDRTAAWLMNVPYIEQEPETELCRDEHTQAEKYQAEISMLQDRLRMSVQRLEEYEARLKGQEEQAQKMLLEYQARLDESEERLRRQQEDKDLQMKGIISRLMSVEEELKKDHADMQAVVDSKQKIIDAQEKRIASLDAANARLMSALSQLKERYSMQTRNGISPTNPTKLQITENGEFRNSSNC", "length": 1180, "header": "tr|A5PF31-1|A5PF31_DANRE Isoform 1 of DAB2 interacting protein b isoform X1 OS=Danio rerio OX=7955 GN=dab2ipb PE=4 SV=1 CANONICAL=A5PF31-1" }, "locus": {} }, { "isoform_ac": "F1RAN5-1", "url": "https://www.uniprot.org/uniprotkb/A5PF31/entry#F1RAN5-1", "sequence": { "sequence": "MSGVTRKGSGRPGYYYRLLGRTRLQRQRSRSRSRSRVTNNKDSPPERTGRRRSIPGSAPDKVPPTMEPTAAAAATPFRVTGFLSRRLKGSIKRTKSQPKLDRNSSFRHILPGFRPVDNERSHLMPRLKESRSHESLLSPTSAVEALDLSMEEEVLIKPVHSSILGQDYCFEVSTSTGSKCFSCRSAAERDKWMENLRRAIHPNKDNSRRVENMLRLWIIEAKDLPAKKKYFCELCLDDSLYARTTCKMKTDNVFWGEHFEFNNLPAVQSITVHVYRDSDKKKKKDKNNYVGLVSIPVVTVTSRQLVEKWYPVSQPNPGKGKAAGPMVRIKARYQSMNILPMELYKEFAEYTTNNYMLLCSVLEPVISVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGENEHLIFRENTLGTKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSSSDLPEHQSNLRMCCELAFCKIIESYRVFPRELKEVFASWRQECGNRGRPDISERLISASLFLRFLCPAIMSPSLFNLTQEYPDDRTARTLTLIAKVTQNLANFTKFGNKEEYMSFMNQFLEQEWTNMQRFLLEISNPETISNTAGFEGYIDLGRELSTLHSLLAEVLSQMDQSAASKLGPLPRILRDVHGALTNPTNVQMSVPSDRVPSPPVPGCSISTGIQKMAIDSDLPGPVDFTRLPSPTPENKDLFFVTRSSGLQGSPTRSSSYSEANEPELGLANGGKSLSMVDLQEAARALEPISIPAGITSEGMGEGAMVPWNARTPQGNIAGGPTLHRPVQSPTTPGAEGAPGRPTQLLAPLSFQNPVYQMAAGLPVSARGNASGDSGSECHSSVSSHSNNEECLGGTKTTFLTQGASVGEEFARRSGDFSRRQLSLTDPQHGNQPTVPRQSSAGPQRRIDQPPPPTQTAPRGRTPPNLLNSGPYPRPLNNTMMSSSPDWPGSGARLRQQSSSSKGDSPETKHRAPHKQAPSPVNPSALDRTAAWLMNVPYIEQEPETELCRDEHTQAEKAEISMLQDRLRMSVQRLEEYEARLKGQEEQAQKMLLEYQARLDESEERLRRQQEDKDLQMKGIISRLMSVEEELKKDHADMQAVVDSKQKIIDAQEKRIASLDAANARLMSALSQLKERYSMQTRNGISPTNPTKLQITENGEFRNSSNC", "length": 1178, "header": "tr|F1RAN5-1|A5PF31_DANRE Computationally mapped isoform of DAB2 interacting protein b isoform X1 OS=Danio rerio OX=7955 GN=dab2ipb PE=4 SV=2 CANONICAL=A5PF31-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 703, "start_aa": "Thr", "end_pos": 703, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr703", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 925, "start_aa": "Thr", "end_pos": 925, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr925", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The zebrafish gene map defines ancestral vertebrate chromosomes.", "journal": "Genome Res.", "date": "2005", "authors": "Woods Ian G, Wilson Catherine, Friedlander Brian, Chang Patricia, Reyes Daengnoy K, Nix Rebecca, Kelly Peter D, Chu Felicia, Postlethwait John H, Talbot William S", "evidence": [ { "database": "UniProtKB", "id": "F1RAN5", "url": "https://www.uniprot.org/uniprotkb/F1RAN5" } ], "reference": [ { "type": "PubMed", "id": "16109975", "url": "https://glygen.org/publication/PubMed/16109975" } ] }, { "title": "Evolutionary history of the ABCB2 genomic region in teleosts.", "journal": "Dev. Comp. Immunol.", "date": "2007", "authors": "Palti Y, Rodriguez M F, Gahr S A, Hansen J D", "evidence": [ { "database": "UniProtKB", "id": "F1RAN5", "url": "https://www.uniprot.org/uniprotkb/F1RAN5" } ], "reference": [ { "type": "PubMed", "id": "17055577", "url": "https://glygen.org/publication/PubMed/17055577" } ] }, { "title": "Zebrafish reward mutants reveal novel transcripts mediating the behavioral effects of amphetamine.", "journal": "Genome Biol.", "date": "2009", "authors": "Webb Katharine J, Norton William Hj, Tr\u00fcmbach Dietrich, Meijer Annemarie H, Ninkovic Jovica, Topp Stefanie, Heck Daniel, Marr Carsten, Wurst Wolfgang, Theis Fabian J, Spaink Herman P, Bally-Cuif Laure", "evidence": [ { "database": "UniProtKB", "id": "F1RAN5", "url": "https://www.uniprot.org/uniprotkb/F1RAN5" } ], "reference": [ { "type": "PubMed", "id": "19646228", "url": "https://glygen.org/publication/PubMed/19646228" } ] }, { "title": "An optimized two-finger archive for ZFN-mediated gene targeting.", "journal": "Nat. Methods", "date": "2012", "authors": "Gupta Ankit, Christensen Ryan G, Rayla Amy L, Lakshmanan Abirami, Stormo Gary D, Wolfe Scot A", "evidence": [ { "database": "UniProtKB", "id": "F1RAN5", "url": "https://www.uniprot.org/uniprotkb/F1RAN5" } ], "reference": [ { "type": "PubMed", "id": "22543349", "url": "https://glygen.org/publication/PubMed/22543349" } ] }, { "title": "Hypoxia-inducible factor 3 is an oxygen-dependent transcription activator and regulates a distinct transcriptional response to hypoxia.", "journal": "Cell Rep.", "date": "2014", "authors": "Zhang P, Yao Q, Lu L, Li Y, Chen PJ, Duan C", "evidence": [ { "database": "UniProtKB", "id": "F1RAN5", "url": "https://www.uniprot.org/uniprotkb/F1RAN5" } ], "reference": [ { "type": "PubMed", "id": "24613356", "url": "https://glygen.org/publication/PubMed/24613356" } ] }, { "title": "Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish.", "journal": "Dev. Cell", "date": "2015", "authors": "Kok F O, Shin M, Ni C-W, Gupta A, Grosse A S, van Impel A, Kirchmaier B C, Peterson-Maduro J, Kourkoulis G, Male I, DeSantis D F, Sheppard-Tindell S, Ebarasi L, Betsholtz C, Schulte-Merker S, Wolfe S A, Lawson N D", "evidence": [ { "database": "UniProtKB", "id": "F1RAN5", "url": "https://www.uniprot.org/uniprotkb/F1RAN5" } ], "reference": [ { "type": "PubMed", "id": "25533206", "url": "https://glygen.org/publication/PubMed/25533206" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "F1RAN5", "url": "https://www.uniprot.org/uniprotkb/F1RAN5" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] }, { "title": "Zebrafish myo7aa affects congenital hearing by regulating Rho-GTPase signaling.", "journal": "Front. Mol. Neurosci.", "date": "2024", "authors": "Xie Binling, Liang Jiaxin, Jiang Jifan, Zeng Ting, Liu Ling, Xie Dinghua, Zhu Ganghua, Xiong Lei, Zhang Kanjia, Liu Dong, Gong Jie, Chen Xiangding, Lai Ruosha, Xie Huaping", "evidence": [ { "database": "UniProtKB", "id": "F1RAN5", "url": "https://www.uniprot.org/uniprotkb/F1RAN5" } ], "reference": [ { "type": "PubMed", "id": "39081296", "url": "https://glygen.org/publication/PubMed/39081296" } ] } ], "pathway": [ { "id": "dre:558237", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558237", "resource": "KEGG Pathway" }, { "id": "R-DRE-5658442", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5658442", "resource": "Reactome", "description": "Regulation of RAS by GAPs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6ABU3-1", "protein_name": "RAS protein activator like 2", "gene_name": "Rasal2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELSPSSGGAAEALSWPEMFSGLESDSPLPPEDLDAVVPVSGAVAGGMLDRILLESVCQQQSWVRVFDVKGPPTHRLSCGQSPYTETTSWERKYCILTDSQLVLLNKEKEIPVDGQDQQADSTKGRCLRRTVSVPSEGQFPEYPPEGTAKLEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNADDRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFITSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELTDHQSNLRMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDLSERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFAEHSSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDEKENSLPNGRSISLMDLQDTHTAQVEHGSVMLDVPMRLAGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGSLQPLSFQNPVYHLNNPVPAMPKASADSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSSHSEDFSRRHTAPDRHIPLALPRQNSTGQSQIRKLDQSGLGARAKAPPSLPHSASLRSTGSMSVASAALVAEPVQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEISKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLEDHLLSGEERKEKAITIKEVSCKETQAVSSSFSVSSSPVFVSTDTFFPPHSRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC", "length": 1332 }, "evidence": [ { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M2B5U5-1", "protein_name": "Ras/Rap GTPase-activating protein SynGAP isoform X1", "gene_name": "syngap1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSYVSSQDGRCVSPCSRPHTPLNGHAHDSPGWSRQLRVRDGDQFYLLDQEEVHPLLMNDHRPVSHRHKLLRRTVSVPADSRPHPESEHARARRKSFATSRQRSMETPPTAPTQPFRQPSFLSRRLKGSIKRAKSQPKLDRTGSFRHMILPRFRSADQERTRLMQSFKESHSHESLLSPSSAAEALDLTLDEDAIIKPVHSSILGQEYCFEVTTASGTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARDLPPKKRYYCELCLDDMLYARTTSKPRTDTVFWGEHFEFNNLPAIRSLRLHLYKENDKKRRKEKSTYLGLVSIPIPSVTGRQFVEQWYPLIQPSVLAKGGGGGGKIINASLRLKSRFQSMNILPMELYKEFAEYVTNNYRTLCGVLEPLLSAKSKEEVACALVHILQSTGKAKDFLSDMAMCEVDRFMDREHLIFRENTLATKAIEEFLKLIAHRYLKDTIGEGEFIRALYESEENCEVDPMRTPPSVLADHQANLRMCCELALCKIINSHCVFPRELKEVFASWRVRCAERGREDIADRLISSSLFLRFLCPAIMSPSLFNLTQEYPSERTSRTLTLIAKVVQSLASFSKFSGKEDYLGFMNEFLEMEWGSMQQFLYEISNLECVSNAGAFEGYIDLGRELSILHSLLWEVMAQLSKDAILKLGPLPRLLNDISVALRNPQLHRQASHQPPERHLSRPAFSRLATNDFQSLMMRDLNSSIDISRLPSPTAGLSGSGVLSHPGMAAFSERDPRGNKDVFYVTRPPLARSSPAYCTSSSDITEPDPKVLSVNKSVSMMDLQDSRINSVSNLHSVNDLLNSSQGSLAGFGPLGGAPLRAGGRVSAGSGGSSMSGGLRLTTDSLSQQQQQAAAAMHVPLSFQNPLFHLASDGPQYHTPPHGPTAVPPPLLLAPEPENGHVGFGVPTFAHSGFSRSEDLSALRTQNSLVQPNIVHSHSYSDDFTRHNQADYARRQLSLQVQENLQQQVLMGMTPQTATGTGTPASLATPPTTIHPVRQASMAPPPPQRAKPQPAHQLSVSSAVNSTPPKTRPQSGNLLQSPESSFGGRQLTRQQLSVKDSPAPGLPHQSSNASENPAPQSAANESTENTPTNQSAKNTQQSNQQHLLKPSGNKQGSKSPSTLNPTSAASERTVAWVSNMPHLSADIESLRVDREEFKLKEHSKSMDESRLDRVREYEEEINSLKERLMMSHRKLEEYERRLHSQEQQTSKILLQYQSRLDDSERRLRQQQVEKDSQIKGIINRLMAVEDELRGSGMPDLKTRIFTEQPIYGAHSGT", "length": 1313 }, "evidence": [ { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BIR4-1", "protein_name": "Ras GTPase-activating protein nGAP isoform X1", "gene_name": "rasal2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLTRLATLEEQTGSNRSPSRSSFGKDSVRRWRLLNRPWLKHRSNSAPEEPLDMHDRRILVRQDMRTQSLTWSRSSSTRPSNPPISRVHSLPDPQRVTSRGVLLEHANLQKDWLSRSSSPFFKSTSELGSEIHTGAPPLRRVSSSHMFSGILLSMSRRISRILNTSPEPAVGELSEDDVKGPASHHFSCGQSPFTEPCVWERKYCILTDSQLILLNKEEEMPSEVHESPSASSSKGRSLRRTVSVPSEGPFPDFPPEGASMIAEASAERSPRRRSISGLGSSEKNISIDGPNSSPFKVPGFLSKRLKGSIKRTKSQTKLDRNTSFRLPSLRPTENDRSRGLPKLKESCSHESLLSPGSAVEALDLSMEEDVYIKPLHSSILGQDFCFEVAYSGGSKCFSCSSAAERDKWMENLKRTVQPNKDNCRRAENVLRLWIIEAKDLPPKKKYFCELCLDDMLYARTTSKTRSDCLFWGEHFEFSGLPSMKSITIHIYRDVDKKKKKDKNNYVGLVNIPVHGVMGRQFVEKWYPVSTPTTSKAKGGGPSIRIKSRFQTISILPMEQYKEFAEFVTNNYTMLCSVLEPVISVKNKEEMASALVHILQSTGRAKDFLTDLVMSEVDRCADHDVLIFRENTLATKAIEEYLKLVGQKYLHDALGEFIKALYESDENCEVDQSKCTSNELPEHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCHARGKQDISQRLISASLFLRFLCPAIMSPSLFGLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWAGMTRFLLEISNLETISNTPGFEGYIDLGRELSVLHSLLWEVVSQLDKGDNSFLQATVAKLGPLPRILGDITRSLSSPTPIQQQLRRFQDHSSAHDISGSVSSGLQRIFEDPADSEMRSIKSPVQEHMEALVRGKHPLLGQQSSAHSMSFSDKEERDSPLPNGRSISLMDLQDSYLAQGHPGPNSLNEASSRLGRVGSQASIGPVPPPHLHQPPVHPKVPQLRDNLPQSAPQVRRPIHPSLSQQRSLQPLSFQNPVYHLSNLHAQSTHSTQSTHSAQSLQPDSSSENLSTGSSRSASPSASGGRGATPRARIPSTSSVEEEFSRRSIQGQETPPPTARWHPPLADQHSGAQVVAVPRQSTTGTAHIVKVEQQSRGVGLVAANAGARTPRSLPHSTSIRSGSSANTEPIQQSGERSRQQSTCSKDGSVPGGRANKQVQSPVESVTMSPVERTAAWVLNNGQYEDEEEEGQSKDDAKHVEKYEQEISKLKERLRTSSRRLEEYERRLLAQEQQMQKLLLEYKTRLEDSEDRLRRQQEEKDSQMKSIICRLMAVEEELKRDHAEMQAVIDAKQKIIDAQEKRISSLDAANSRLMSALTQVKERYSMHNLRNGLSPTNPTKLSITENGEFKNSSC", "length": 1432 }, "evidence": [ { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YZX5-1", "protein_name": "Disabled homolog 2-interacting protein isoform X1", "gene_name": "dab2ipa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFGGPTPISPHITRCQHQGWMRVTDMKGSSVHWLSCGQPLSEPIGWQVKFCLVAECQLVLLDKREISPLLFQERRAESCTVWLLRRSTSIPEGVQLRKDQSTQTRNTKSLADRVGRRRSMPGSTVDKTVVAMDADTSTPFKVTGFLSRRLKGSIKRTKSQPKLDRHSSFRNILPGFKSAENDSRSHLMPRLKESRSHESLLSPSSAVEALDLSMEEEVLIKPVHSSILGQDFCFEVTTSTGSKCFSCRSAAERDKWMENLRRAVHPNKDNTRRVENMLKCWIIEAKDLPAKKKYFCELCLDDTLYARTTCKLKTDNVFWGEHFEFNNLPSVKSITVHLYKETDKKKKKDKNNYVGLVNIPIATVTGRQFVEKWYSVSTPNPNKGKSPGPMVRMKSRYQSMSILPMELYKEFAEYITNNYMLMCSVLEPALSVKNKEEMACALVHILQSTGKAKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSSSDLHEHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLISASLFLRFLCPAIMSPSLFSLMQEYPDDRTARTLTLIAKVTQNLANFTKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISNPETISNTAGFEGYVDLGRELSSLHSLLSEAVSQLDQTTITKLGPLARILRDVNSALTNPTGAPVPSPTERVGSPSLPSSSLSTGLQKMVMDSEITGLVDFTRLPSPTPENKDLFFVTRNSVIQPSPARSSSYSEANEPDVQIPNGSKSLSMVDLQDSRSLESAANTSFSDPINDSQASAGQSAGMWTTRTIKGNTPSGPTLRRAGQTPTTPSTESAPGRSQLLAPLSFQNPVYQMAAGLPVSPRAVADSGSECQSSISSNAEEAATAGPKHPFISQSSTGASGGGGSSGDEFIQRPGEFTRRQLSLTETQHQTNVPRQNSAGPQRRIDQPPPAITRGRTPPNMLNTAPYPRPSSGSMMSSSPDWPSSGTRLRQQSSSSKGDSPESKQRTLHKQAPSPVNPNALDRTAAWLLNMNVQYLEQEGIDPDSKHREDFPNKEDLTPTEKYQHEIAVLQEKLRISAKKLEEYESRMKSQDDQTQKMLLEYQARLEDTEERLRKQQDDKELQMKSIITRLMSVEEELKKDHSDMQAIVDSKQKIIEAQEKRIASLDAANARLMSALSQLKDRYSMQTRNGISPTNPTKLQITENGEFRNSSNC", "length": 1256 }, "evidence": [ { "id": "MGI:1916851", "url": "https://alliancegenome.org/gene/MGI:1916851#orthology", "database": "AGR" }, { "id": "HGNC:17294", "url": "https://alliancegenome.org/gene/HGNC:17294#orthology", "database": "AGR" }, { "id": "RGD:621686", "url": "https://alliancegenome.org/gene/RGD:621686#orthology", "database": "AGR" }, { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZWW3-1", "protein_name": "RAS protein activator like 3", "gene_name": "Rasal3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPPLQNEDSQTQPSPLTSYRWHTGGRGEKIAGGFRWGRFAGWGRALSHQEPMVSSQPAPRSLFRRVLSAPPKESRPNRLRFSKSLWGRHKNVVPLEPKLNPKAPEPELELEGAPDLRAAHIPEPPAPDMPVWNIDGFALLEGRLVMLGEEEGPRQIRMGSASSESSMQAALGNLKDPVRTPGKIEPEATGSNQVHNVRKLLKRLKEKKRAKSELGAHTPRDGPSSALGSRESLATLSELDLGVERDVRVWPLHPSLLGEPYCFQVTWAGGSRCFSCRSSAERDRWIEDLRRQFQPSQDNVERQETWLTVWVHEAKGLPRAAAPGVRAELWLDGALLARTAPRAGPDQLFWAERFHFEALPPARRLSLRLRGAGPAGATVGRVVLELDEVSIPRAPAAGLERWFPVLGAPAGAVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCMALEPALSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELERCGGREALLFRENTLATKAIDEYMKLVAQEYLQETLGQVVRSLCASTEDCEVDPSKCPTPELPKCQARLRSSCEEVFENIIHSYNYFPAELGTVFSNWREACKARGSEALGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMVFMNSFLEDHGPAMRHFLDQVAMVDTDTTPSGYQGSGDLALQLAVLHVQLCTIFAELDQKTRDSLEPLPTILQAIEEGRPVPVSVPMRLPLNTAHVQSSFSSGEKPGFLAPRDLPKHTPLISKSQSLRSFQGAGSWARRRPDGERPQRRPRPVLRTQSVPARRPTHHRPAAGSKPRPKGSLRTGPATSGRAWARTSTSLPRKPSVPWQRQLDQPGDRYQTPGTHRPVGKLAEIQCEVAALREEQKALSHLVESLSTHIQALTEQQEQLRCQLQDLDSRLGAGISKLDSKGGLPSNGSLGLKSLEHRMTEMECSQNQLRDTLQSLQLLSKTPGSRSQPPPLKAPCVNGADLSMGT", "length": 1015 }, "evidence": [ { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PW37-1", "protein_name": "RAS protein activator like 2", "gene_name": "Rasal2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELSPSSGGAAEALSWPEMFTGLESDSPLPPEDLDAVVPVSGAVAGGMLDRILLESVCQQQSWVRVFDVKGPPTHRLSCGQSPYTETTSWERKYCILTDSQLVLLNKEKEMPVEGQDQQTDSTKGRCLRRTVSVPSEGQFPEYPQEGTTKLEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRNADDRSRGLPKLKESRSHESLLSPCSAVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCSSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFYSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFITSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELMDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFAEHSSSPNVSGSLSSGLQRICEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDEKENSLPNGRSISLMDLQDTHAAQAEHASVMLDVPMRLAGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGSLQPLSFQNPVYHLNNPVPAMPKASADSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSSHSEDFSRRHTVPDRHIPLALPRQNSTGQSQIRKLDHSGLGARAKAPPSLPHSASLRSTGSMSVASAALMAEPVQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNQDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC", "length": 1286 }, "evidence": [ { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F6SEU4-1", "protein_name": "Ras/Rap GTPase-activating protein SynGAP", "gene_name": "Syngap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRSRASIHRGSIPAMSYAPFRDVRGPPMHRTQYVHSPYDRPGWNPRFCIISGNQLLMLDEDEIHPLLIRDRRSESSRNKLLRRTVSVPVEGRPHGEHEYHLGRSRRKSVPGGKQYSMEAAPAAPFRPSQGFLSRRLKSSIKRTKSQPKLDRTSSFRQILPRFRSADHDRARLMQSFKESHSHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEFCFEVTTSSGTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREHLIFRENTLATKAIEEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQANLRMCCELALCKVVNSHCVFPRELKEVFASWRLRCAERGREDIADRLISASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLDTLTNSSSFEGYIDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTALRNPNIQRQPSRQSERTRSQPMVLRGPSAEMQGYMMRDLNSSIDLQSFMARGLNSSMDMARLPSPTKEKPPPPPPGGGKDLFYVSRPPLARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDGPGGRLNSSSVSNLAAVGDLLHSSQASLTAALGLRPAPAGRLSQGSGSSITAAGMRLSQMGVTTDGVPAQQLRIPLSFQNPLFHMAADGPGPPAGHGGSSGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSKSEDLSSGVPKPPAASILHSHSYSDEFGPSGTDFTRRQLSLQDSLQHMLSPPQITIGPQRPAPSGPGGGSGGGSGGGQPPPLQRGKSQQLTVSAAQKPRPSSGNLLQSPEPSYGPARPRQQSLSKEGSIGGSGGSGGGGGGGLKPSITKQHSQTPSTLNPTMPASERTVAWVSNMPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRKLEEYERRLLSQEEQTSKILMQYQARLEQSEKRLRQQQVEKDSQIKSIIGRLMLVEEELRRDHPAMAEPLPEPKKRLLDAQERQLPPLGPTNPRVTLAPPWNGLAPPAPPPPPRLQITENGEFRNTADH", "length": 1340 }, "evidence": [ { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P33314-1", "protein_name": "Inhibitory regulator protein BUD2/CLA2", "gene_name": "BUD2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSSNNEPAQSRTSYFKLNEFLSNVKHYKNTFKGEIQWCNNLSLNDWKTHYLQITSTGALTHSIDELTADSTNIQPIIKHLQQCRIEIIKDKHSSFKDINANCNFIIQVNTSGKDNKVYLRVKSWSDFKKLLTCLIWWSSMKTNGIFNKFQVSRPLEFKSKKMAKPESLLVYKLNVFGPIVKNIVLPPATNILESPDIINNDDNSVGWFSAMGVLKSNGMLDLLLQSDGSLIYSLNISQLLRSEIRILDSSVLQSENSLFLGELPLLRSQLGLEKFRIENIASAATNSSDISQEIIVEFPLRIDLEDCFIALQSFARSEYLSITGSDKSNDMKISNSFKISILEANFQSINLNDKNNTPWSIFTDITAWGHTWARTSMVSNSSNPFWREEFQFNELLRLTNSYLEIKQLFHDLNNKKRLRLIGKIKITQEIINDTRYNKETRLPIMDVDNKNFQIGTICIKISSNLNFILPSTNFVKLEKLLMNANLSMVSNLIYKSSSSMENDNKLTQTSIIFLDIFQSLSRIEEWFHVLIDKELAKIDGTVSRINQKNLDSKHVFNSLFRGNSILTKSIEQYFFRVGNEYLSKALSAILKEIIESNKSCELDPARVKEKDEVKKRKIIADNYKRLYSWVTKIWKRLYATSNDLPIEIRNVLKIFRQKLEIICIDDTLQIILNGISGLLFLRFFCPVILNPKLFKYVSQNLNETARRNLTLISKVLLNLSTLTQFANKEPWLMKMNNFIDKRHNDLLDYIDKMTQKKLDFNSKILNLSSTISRPKLAIEQTMLDDLPQIPYLLDKNLRETEFVNLIVNFSQEDMTKMEKYNHMDNGGKGELIEEEGLLSGSSLNLSVDKKDLDSPIEVKPEIGELEFEKITENNTEIFGDDLMNLLKSDDVGSRSRDLDNGANSGIKFNSIIPKAEEEKHAMKELEQESCLLYNRINHIRKRLSGYECASSTLFEDKKYSISLSHKIFYEEIKEGKEIVLKLLNKPTNENSSARLQKFFTKGVSSKSNNTVGDSYCKFLTIDVSDENPKSSNKTSVHGTSSENGAKDDYLTLPNSQGKGNLGNRFSPTKLSRIMRKPPNADVPKEQNSRKLTRWFKKKKETGGS", "length": 1104 }, "evidence": [ { "id": "MGI:1916851", "url": "https://alliancegenome.org/gene/MGI:1916851#orthology", "database": "AGR" }, { "id": "HGNC:17294", "url": "https://alliancegenome.org/gene/HGNC:17294#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2449", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2449#orthology", "database": "AGR" }, { "id": "RGD:621686", "url": "https://alliancegenome.org/gene/RGD:621686#orthology", "database": "AGR" }, { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3UHC7-1", "protein_name": "Disabled homolog 2-interacting protein", "gene_name": "Dab2ip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAGGNARKSTGRPSYYYRLLRRPRLQRQRSRSRSRTRPARESPQERPGSRRSLPGSMSEKNPSMEPSASTPFRVTGFLSRRLKGSIKRTKSQPKLDRNHSFRHILPGFRSAAAAAADNERSHLMPRLKESRSHESLLSPSSAVEALDLSMEEEVIIKPVHSSILGQDYCFEVTTSSGSKCFSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTSKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNPKGGKGPGPMIRIKARYQTVSILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSSADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISNPETLSNTAGFEGYIDLGRELSSLHSLLWEAVSQLDQSVVSKLGPLPRILRDVHTALSTPGSGQLPGTNDLASTPGSGSSSVSAGLQKMVIENDLSGLIDFTRLPSPTPENKDLFFVTRSSGVQPSPARSSSYSEANEPDLQMANGSKSLSMVDLQDARTLDGEAGSPVGPDALPADGQVPATQLLAGWPARAAPVSLAGLATVRRAVPTPTTPGTSEGAPGRPQLLAPLSFQNPVYQMAAGLPLSPRGLGDSGSEGHSSLSSHSNSEELAAAAKLGSFSTAAEELARRPGELARRQMSLTEKGGQPTVPRQNSAGPQRRIDQPPPPPPPPPPAPRGRTPPTLLSTLQYPRPSSGTLASASPDWAGPGTRLRQQSSSSKGDSPELKPRAMHKQGPSPVSPNALDRTAAWLLTMNAQLLEDEGLGPDPPHRDRLRSKEELSQAEKDLAVLQDKLRISTKKLEEYETLFKCQEETTQKLVLEYQARLEEGEERLRRQQEDKDIQMKGIISRLMSVEEELKKDHAEMQAAVDSKQKIIDAQEKRIASLDAANARLMSALTQLKERYSMQARNGVSPTNPTKLQITENGEFRNSSNC", "length": 1189 }, "evidence": [ { "id": "MGI:1916851", "url": "https://alliancegenome.org/gene/MGI:1916851#orthology", "database": "AGR" }, { "id": "HGNC:17294", "url": "https://alliancegenome.org/gene/HGNC:17294#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2449", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2449#orthology", "database": "AGR" }, { "id": "RGD:621686", "url": "https://alliancegenome.org/gene/RGD:621686#orthology", "database": "AGR" }, { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" }, { "id": "A5PF31", "url": "https://omabrowser.org/oma/group/A5PF31/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5VWQ8-1", "protein_name": "Disabled homolog 2-interacting protein", "gene_name": "DAB2IP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAGGSARKSTGRSSYYYRLLRRPRLQRQRSRSRSRTRPARESPQERPGSRRSLPGSLSEKSPSMEPSAATPFRVTGFLSRRLKGSIKRTKSQPKLDRNHSFRHILPGFRSAAAAAADNERSHLMPRLKESRSHESLLSPSSAVEALDLSMEEEVVIKPVHSSILGQDYCFEVTTSSGSKCFSCRSAAERDKWMENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNPKGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSAADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISNPETLSNTAGFEGYIDLGRELSSLHSLLWEAVSQLEQSIVSKLGPLPRILRDVHTALSTPGSGQLPGTNDLASTPGSGSSSISAGLQKMVIENDLSGLIDFTRLPSPTPENKDLFFVTRSSGVQPSPARSSSYSEANEPDLQMANGGKSLSMVDLQDARTLDGEAGSPAGPDVLPTDGQAAAAQLVAGWPARATPVNLAGLATVRRAGQTPTTPGTSEGAPGRPQLLAPLSFQNPVYQMAAGLPLSPRGLGDSGSEGHSSLSSHSNSEELAAAAKLGSFSTAAEELARRPGELARRQMSLTEKGGQPTVPRQNSAGPQRRIDQPPPPPPPPPPAPRGRTPPNLLSTLQYPRPSSGTLASASPDWVGPSTRLRQQSSSSKGDSPELKPRAVHKQGPSPVSPNALDRTAAWLLTMNAQLLEDEGLGPDPPHRDRLRSKDELSQAEKDLAVLQDKLRISTKKLEEYETLFKCQEETTQKLVLEYQARLEEGEERLRRQQEDKDIQMKGIISRLMSVEEELKKDHAEMQAAVDSKQKIIDAQEKRIASLDAANARLMSALTQLKERYSMQARNGISPTNPTKLQITENGEFRNSSNC", "length": 1189 }, "evidence": [ { "id": "MGI:1916851", "url": "https://alliancegenome.org/gene/MGI:1916851#orthology", "database": "AGR" }, { "id": "HGNC:17294", "url": "https://alliancegenome.org/gene/HGNC:17294#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2449", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2449#orthology", "database": "AGR" }, { "id": "RGD:621686", "url": "https://alliancegenome.org/gene/RGD:621686#orthology", "database": "AGR" }, { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" }, { "id": "A5PF31", "url": "https://omabrowser.org/oma/group/A5PF31/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P730-1", "protein_name": "Disabled homolog 2-interacting protein", "gene_name": "Dab2ip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MENLRRAVHPNKDNSRRVEHILKLWVIEAKDLPAKKKYLCELCLDDVLYARTTGKLKTDNVFWGEHFEFHNLPPLRTVTVHLYRETDKKKKKERNSYLGLVSLPAASVAGRQFVEKWYPVVTPNPKGGKGPGPMIRIKARYQTITILPMEMYKEFAEHITNHYLGLCAALEPILSAKTKEEMASALVHILQSTGKVKDFLTDLMMSEVDRCGDNEHLIFRENTLATKAIEEYLKLVGQKYLQDALGEFIKALYESDENCEVDPSKCSAADLPEHQGNLKMCCELAFCKIINSYCVFPRELKEVFASWRQECSSRGRPDISERLISASLFLRFLCPAIMSPSLFNLLQEYPDDRTARTLTLIAKVTQNLANFAKFGSKEEYMSFMNQFLEHEWTNMQRFLLEISNPETLSNTAGFEGYIDLGRELSSLHSLLWEAVSQLDQSIVSKLGPLPRILRDVHTALSTPGSGQLPGTNDLASTPGSGSSSVSAGLQKMVIENDLSGLIDFTRLPSPTPENKDLFFVTRSSGVQPSPARSSSYSEANEPDLQMANGSKSLSMVDLQDARTLDGEAGSPVGPEALPADGQVPATQLVAGWPARAAPVSLAGLATVRRAVPTPTTPGTSEGAPGRPQLLAPLSFQNPVYQMAAGLPLSPRGLGDSGSEGHSSLSSHSNSEELAAAAKLGSFSTAAEELARRPGELARRQMSLTEKGGQPTVPRQNSAGPQRRIDQPPPPPPPPPPAPRGRTPPTMLSTLQYPRPSSGTLASASPDWAGPGTRLRQQSSSSKGDSPELKPRALHKQGPSPVSPNALDRTAAWLLTMNAQLLEDEGLGPDPPHRDRLRSKEELSQAEKDLAVLQDKLRISTKKLEEYETLFKCQEETTQKLVLEYQARLEEGEERLRRQQEDKDVQMKGIISRLMSVEEELKKDHAEMQAAVDSKQKIIDAQEKRIASLDAANARLMSALTQLKERYSMRARNGVSPTNPTKLQITENGEFRNSSNC", "length": 996 }, "evidence": [ { "id": "MGI:1916851", "url": "https://alliancegenome.org/gene/MGI:1916851#orthology", "database": "AGR" }, { "id": "HGNC:17294", "url": "https://alliancegenome.org/gene/HGNC:17294#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2449", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2449#orthology", "database": "AGR" }, { "id": "RGD:621686", "url": "https://alliancegenome.org/gene/RGD:621686#orthology", "database": "AGR" }, { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" }, { "id": "A5PF31", "url": "https://omabrowser.org/oma/group/A5PF31/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86YV0-1", "protein_name": "RAS protein activator like-3", "gene_name": "RASAL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPPSPSRTSQTQPTATSPLTSYRWHTGGGGEKAAGGFRWGRFAGWGRALSHQEPMVSTQPAPRSIFRRVLSAPPKESRTSRLRLSKALWGRHKNPPPEPDPEPEQEAPELEPEPELEPPTPQIPEAPTPNVPVWDIGGFTLLDGKLVLLGGEEEGPRRPRVGSASSEGSIHVAMGNFRDPDRMPGKTEPETAGPNQVHNVRGLLKRLKEKKKARLEPRDGPPSALGSRESLATLSELDLGAERDVRIWPLHPSLLGEPHCFQVTWTGGSRCFSCRSAAERDRWIEDLRRQFQPTQDNVEREETWLSVWVHEAKGLPRAAAGAPGVRAELWLDGALLARTAPRAGPGQLFWAERFHFEALPPARRLSLRLRGLGPGSAVLGRVALALEELDAPRAPAAGLERWFPLLGAPAGAALRARIRARRLRVLPSERYKELAEFLTFHYARLCGALEPALPAQAKEELAAAMVRVLRATGRAQALVTDLGTAELARCGGREALLFRENTLATKAIDEYMKLVAQDYLQETLGQVVRRLCASTEDCEVDPSKCPASELPEHQARLRNSCEEVFETIIHSYDWFPAELGIVFSSWREACKERGSEVLGPRLVCASLFLRLLCPAILAPSLFGLAPDHPAPGPARTLTLIAKVIQNLANRAPFGEKEAYMGFMNSFLEEHGPAMQCFLDQVAMVDVDAAPSGYQGSGDLALQLAVLHAQLCTIFAELDQTTRDTLEPLPTILRAIEEGQPVLVSVPMRLPLPPAQVHSSLSAGEKPGFLAPRDLPKHTPLISKSQSLRSVRRSESWARPRPDEERPLRRPRPVQRTQSVPVRRPARRRQSAGPWPRPKGSLSMGPAPRARPWTRDSASLPRKPSVPWQRQMDQPQDRNQALGTHRPVNKLAELQCEVAALREEQKVLSRLVESLSTQIRALTEQQEQLRGQLQDLDSRLRAGSSEFDSEHNLTSNEGHSLKNLEHRLNEMERTQAQLRDAVQSLQLSPRTRGSWSQPQPLKAPCLNGDTT", "length": 1011 }, "evidence": [ { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C2K5-1", "protein_name": "RAS protein activator like-3", "gene_name": "Rasal3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPECGQTMFRTFWSRSRDSSAMDPPLQSEEDSQTQPSLPSPLTSYRWHTGGSGEKAAGGFRWGRFAGWGRALSHQEPMVNSQPAPRSLFRRVLSAPPKESRSNRLRFSKTLWGRHKNVAPLEPKPNPKAPEPELELVADPDLPVAQIPEPPTPDMPVWNIDGFTLLEGKLVMLGEEEGPRQIRVGSASSENSMQAALGNLKDAVRTPGKTEPEAAGSNQVHNVRKLLKRLKEKKRAKSELGAYTPRDGPPSALGSRESLATLSELDLGAERDVRVWPLHPSLLGEPYCFQVTWAGGSLCFSCRSSAERDRWIEDLRRQFQPSQDNVERQEMWLTVWVHEAKGLPRATVPGVRAELWLDGALLARTAPRAGPGQLFWAERFHFEALPPARRLSLRLRSAGPAGATVGRVVLELDEVSIPRAPAAGLERWFPVLGAPAGAVLRARIRVRCLRVLPSERYKELAEFLTFHYARLCGALEPALSAQAKEELAAAMVRVLRATGRAQALVTDLGTAELARCGGREALLFRENTLATKAIDEYMKLVAQEYLQDTLGQVVRCLCASTEDCEVDPSKCPTPELPKHQARLRDSCEEVFENIIHSYNCFPAELGSVFSSWREACKARGSEALGPRLVCASLFLRLLCPAILAPSLFGLAPEHPAPGPARTLTLIAKVIQNLANCAPFGEKEAYMAFMNSFLEDHGPAMQHFLDQVATVDADTTPSGYQGSGDLALQLAVLHVQLCTIFAELDQKTQDSLEPLPTILRAIEEGRPVPVSVPMRLPRISTQVQSSFFSGEKPGFLAPRDLPKHTPLISKSQSLRSFQGAGSWASRRPDEERPQRRPRPVLRTQSVPARRPTHRRPSAGSKPRPKGSLRMGPAPCGRAWTRASASLPRKPSVPWQRQMDQPGDRYQTTGTHRPVGKLAEIQCEVAIFREAQKALSLLVESLSTQVQALKEQQEHFRCQLQDLYSRLGAGISKLDSKGGLPSNGSHRLKSLEQRLTEMECSQDQLRDSLQSLQLLSKTPGSRSQPLPLKAPCVNGADLSMGT", "length": 1041 }, "evidence": [ { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IR23-1", "protein_name": "Vacuolar peduncle, isoform A", "gene_name": "vap", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MADLIHLGNIDVVIQKDKPGSPTGCSDDGNLAGLGGMTGLGGIMAPGGIDLGDLAQELDHDEFDGPHMLNGERPAIIAPPESEWYHGRLDRYSAESRLRGSSKLGSYLVRESDRKPGSYVLSYYGRTGINHFRITAVCGDFYIGGRQFISLSDLVGYYTSCSDLLKRERLAIPVAPPEPVNDKKRVVAILPYTKMPETDELSFQKGDIFFVHNDMGDGWLWVTAHRTGEQGMIFRELVDDLDVSIDPNTVFPWFHPNCTKNEAVDMLVKAGPGSFLVRPSDNSPGDYSLFFHINNQIQRFRIEKKGVRYLMGGRTFECLDAVINRYRKEQIVEGHSLNHPVVNGIQPEFNQQYVVEKAAEKIYATLRECRDQIGLKKIKGIKHHGHLNKKSDKTTKWKQLYFALINDGSETQLCFYDNPKKTKPKGLIDLSCAYLYQCHDSLWERPYCFQIVERALPCLATVTYLCAPSQESYVEWINSLKAQCDSQLSRAQKKVSRLRELRCLNLHVLEAHRLPFKLVPHPYCSISLNQVKVGKTRVKIAPEPVWEEEFVLDDVPPDVVSLTITLISRGKRGKDSEVAELTIDLSSLKNGQETEGWYQLTGMTPMGEWGSLRLRMRYLDDLIMPCEEYSPLQQLLLESELYAVKALAELCHNDRVPLATALLRVFRQEKRETELIRMLCQAEVTRENETTTLFRGASLATTLMDLYMRTECSGFLQSAVSETVQRILESKQSAELNPTKMDVNDDACTNAEFLLQILDLVTQSIFTSPDACPRNVRFICSCLQKAVMAKWPTERLVRTRVVSGFIFLRLLCPALLNPRQFGLVSETPPMAATRSLVMVAKCLQNLANLIEFGGKEQYMEVVNPFILKNKERMIVFLDQLSSVNDPNQPLGMFVEQSTNLNSQDTGRELATLHHICVSHSQELHELSNILSIKKLVTVTDMLTKHKLKYREMIS", "length": 954 }, "evidence": [ { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8T498-1", "protein_name": "Ras GTPase-activating protein raskol", "gene_name": "raskol", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGRRTYLSRSSTISYPSRIEGWLDVCETEGELTRLIKTLPWGPLYCVLQQDDQTFTAYCSEEISLGDVCYEDIPRVRLDRVRRPAKALWDGPPTLVEENEDSDSCVGGSGGMSGINDIVLNTTLYSELGEYKSKTLPRIHFDTALNDTSLNEDTSYEKACRRGSAPTTPILGSKQHQTEHNATSRFTNFFSKKSNPLKRTKSVTKLERTKRGSGGLRGSRSHESLLSSHAVMSTIDLSCTGAVGVAPVHQSVLGRRHCFQVRGGPRGERYYSCGSRQERDLWIYSLRKSIAPNAEHTRRTDNSLKMWVYEAKNLPPKKRYFCELQLDKTLYGRTSVKLQTDLLFWGEHFDFPDIPEINVITVNVFREVDKKKKRDKYQFVGSVKIPVHDVTSRLPCEQWYPILSDKAGDSLGRTSGGGGSGSKDKEQLPTLRIKCRFQSTDILPINVYGNFLTYLKENYKRVCETLEPVIGVKAKEDIGQALVLLMHAQGLAGAFLTDVVALDLLRVGDQRLTFRGNSLATKSMEAFLKLTGEQYLQDTLSAPINELIQSERDCEVDPTKTSGSSAGSLQRQQAALRGAVRGAWQCIFESHKHFPAQLRNCFATFRERLQQLGRQDMADNLISASIFLRFLCPAILSPSLFNITSELPSARATRNLTLVAKTLQTLANFTRFQGKENFMEFLNDFLEQEAARMQQFLEIISTRPEHPAPDSILDWAGYIDQGKQLSILHSLLSESLAKLPEARQHELDPLQHILDEISRAKEHGMGTALPGGYLPATSSTHSIASENQENRNPGSSGSHAGSNSEQLLPQQSQLAQPQHAIVSKPLSAERGIMRGVLTPNSLEKNIFRYNDPTVNGLLQQQQQQQQQQQQQQQQHQQLQQHGHQQQPHHQHPLQMLSNSQTSIAGNQYMSSPGGLQHAQSQTSMASSSLNGSSSNLLHGHQQHAHHPQQLHPHHCPPAPQTSASSTMERMDRMNYPYMSHNGNDYETSTPSSTRSRTLPRNGNPNANGNVGSSNNNQSGSYDDMHGEFQIQISGFDTSSAFVCKSPTPMMKSSLGPAGAGRSHHKLNLGIPDHSGGYVRGNNLNPNSNMPKNLEDLDDLFKYAEEHDVAEPANHHNHNQGQQNHQGHLKPAAVPGKEQLSAKSSHCSSGYQSISTNPSPSQSSSPVESQLKAAMGSHNAPLAFKNPSYQLQPQTGSSRSSAQSNTHQQQQQQQQQQFGSRLKPIGGGLVAARAAFLNSGGALEAATLTPSSSDEQLSADNYFSYAAAAAAGAGIATKLEAQRSLSGGSSSSTSASASTSNLGKSGGSSAYGRLNGPLKREDVYGSGYGGSSGNVGYGLSTSSAAGHHQHPHQQQQNPMQQQQQRERDQEHKQYAGSVAGSVGSATSAAQRRLSLDSARTLSDSSTDTEGHCNQLQEGKRRRQLRSSGGSGGGGAGSEQGLGKSYDQNGEIQLLQQTLDTLCHTLDRDEAELRDSSDELFGLQRPAGSNGSNNLSLQSESTMRSIIDRLITMEEELRREQLKMSLALSHKQRVIEEQGQQIAALDAANSRLLSALTALRQRYETQQQQQQHQAPPKTQKPQ", "length": 1580 }, "evidence": [ { "id": "MGI:1916851", "url": "https://alliancegenome.org/gene/MGI:1916851#orthology", "database": "AGR" }, { "id": "HGNC:17294", "url": "https://alliancegenome.org/gene/HGNC:17294#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2449", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2449#orthology", "database": "AGR" }, { "id": "RGD:621686", "url": "https://alliancegenome.org/gene/RGD:621686#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q96PV0-1", "protein_name": "Ras/Rap GTPase-activating protein SynGAP", "gene_name": "SYNGAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRSRASIHRGSIPAMSYAPFRDVRGPSMHRTQYVHSPYDRPGWNPRFCIISGNQLLMLDEDEIHPLLIRDRRSESSRNKLLRRTVSVPVEGRPHGEHEYHLGRSRRKSVPGGKQYSMEGAPAAPFRPSQGFLSRRLKSSIKRTKSQPKLDRTSSFRQILPRFRSADHDRARLMQSFKESHSHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEFCFEVTTSSGTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREHLIFRENTLATKAIEEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQANLRMCCELALCKVVNSHCVFPRELKEVFASWRLRCAERGREDIADRLISASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLDTLTNSSSFEGYIDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLNDISTALRNPNIQRQPSRQSERPRPQPVVLRGPSAEMQGYMMRDLNSSIDLQSFMARGLNSSMDMARLPSPTKEKPPPPPPGGGKDLFYVSRPPLARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDGPGGRLNSSSVSNLAAVGDLLHSSQASLTAALGLRPAPAGRLSQGSGSSITAAGMRLSQMGVTTDGVPAQQLRIPLSFQNPLFHMAADGPGPPGGHGGGGGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSKSEDLSSGVPKPPAASILHSHSYSDEFGPSGTDFTRRQLSLQDNLQHMLSPPQITIGPQRPAPSGPGGGSGGGSGGGGGGQPPPLQRGKSQQLTVSAAQKPRPSSGNLLQSPEPSYGPARPRQQSLSKEGSIGGSGGSGGGGGGGLKPSITKQHSQTPSTLNPTMPASERTVAWVSNMPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRKLEEYERRLLSQEEQTSKILMQYQARLEQSEKRLRQQQAEKDSQIKSIIGRLMLVEEELRRDHPAMAEPLPEPKKRLLDAQERQLPPLGPTNPRVTLAPPWNGLAPPAPPPPPRLQITENGEFRNTADH", "length": 1343 }, "evidence": [ { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QUH6-1", "protein_name": "Ras/Rap GTPase-activating protein SynGAP", "gene_name": "Syngap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSRASIHRGSIPAMSYAPFRDVRGPPMHRTQYVHSPYDRPGWNPRFCIISGNQLLMLDEDEIHPLLIRDRRSESSRNKLLRRTVSVPVEGRPHGEHEYHLGRSRRKSVPGGKQYSMEAAPAAPFRPSQGFLSRRLKSSIKRTKSQPKLDRTSSFRQILPRFRSADHDRARLMQSFKESHSHESLLSPSSAAEALELNLDEDSIIKPVHSSILGQEFCFEVTTSSGTKCFACRSAAERDKWIENLQRAVKPNKDNSRRVDNVLKLWIIEARELPPKKRYYCELCLDDMLYARTTSKPRSASGDTVFWGEHFEFNNLPAVRALRLHLYRDSDKKRKKDKAGYVGLVTVPVATLAGRHFTEQWYPVTLPTGSGGSGGMGSGGGGGSGGGSGGKGKGGCPAVRLKARYQTMSILPMELYKEFAEYVTNHYRMLCAVLEPALNVKGKEEVASALVHILQSTGKAKDFLSDMAMSEVDRFMEREHLIFRENTLATKAIEEYMRLIGQKYLKDAIGEFIRALYESEENCEVDPIKCTASSLAEHQANLRMCCELALCKVVNSHCVFPRELKEVFASWRLRCAERGREDIADRLISASLFLRFLCPAIMSPSLFGLMQEYPDEQTSRTLTLIAKVIQNLANFSKFTSKEDFLGFMNEFLELEWGSMQQFLYEISNLDTLTNSSSFEGYIDLGRELSTLHALLWEVLPQLSKEALLKLGPLPRLLSDISTALRNPNIQRQPSRQSERARSQPMVLRGPSAEMQGYMMRDLNSSIDLQSFMARGLNSSMDMARLPSPTKEKPPPPPPGGGKDLFYVSRPPLARSSPAYCTSSSDITEPEQKMLSVNKSVSMLDLQGDGPGGRLNSSSVSNLAAVGDLLHSSQASLTAALGLRPAPAGRLSQGSGSSITAAGMRLSQMGVTTDGVPAQQLRIPLSFQNPLFHMAADGPGPPAGHGGSSGHGPPSSHHHHHHHHHHRGGEPPGDTFAPFHGYSKSEDLSTGVPKPPAASILHSHSYSDEFGPSGTDFTRRQLSLQDNLQHMLSPPQITIGPQRPAPSGPGGGSGGGSGGGGGGQPPPLQRGKSQQLTVSAAQKPRPSSGNLLQSPEPSYGPARPRQQSLSKEGSIGGSGGSGGGGGGGLKPSITKQHSQTPSTLNPTMPASERTVAWVSNMPHLSADIESAHIEREEYKLKEYSKSMDESRLDRVKEYEEEIHSLKERLHMSNRKLEEYERRLLSQEEQTSKILMQYQARLEQSEKRLRQQQVEKDSQIKSIIGRLMLVEEELRRDHPAMAEPLPEPKKRLLDAQRGSFPPWVQQTRV", "length": 1308 }, "evidence": [ { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9UJF2-1", "protein_name": "Ras GTPase-activating protein nGAP", "gene_name": "RASAL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQTPEVPAERSPRRRSISGTSTSEKPNSMDTANTSPFKVPGFFSKRLKGSIKRTKSQSKLDRNTSFRLPSLRSTDDRSRGLPKLKESRSHESLLSPCSTVECLDLGRGEPVSVKPLHSSILGQDFCFEVTYLSGSKCFSCNSASERDKWMENLRRTVQPNKDNCRRAENVLRLWIIEAKDLAPKKKYFCELCLDDTLFARTTSKTKADNIFWGEHFEFFSLPPLHSITVHIYKDVEKKKKKDKNNYVGLVNIPTASVTGRQFVEKWYPVSTPTPNKGKTGGPSIRIKSRFQTITILPMEQYKEFAEFVTSNYTMLCSVLEPVISVRNKEELACALVHILQSTGRAKDFLTDLVMSEVDRCGEHDVLIFRENTIATKSIEEYLKLVGQQYLHDALGEFIKALYESDENCEVDPSKCSSSELIDHQSNLKMCCELAFCKIINSYCVFPRELKEVFASWKQQCLNRGKQDISERLISASLFLRFLCPAIMSPSLFNLMQEYPDDRTSRTLTLIAKVIQNLANFAKFGNKEEYMAFMNDFLEHEWGGMKRFLLEISNPDTISNTPGFDGYIDLGRELSVLHSLLWEVVSQLDKGENSFLQATVAKLGPLPRVLADITKSLTNPTPIQQQLRRFTEHNSSPNVSGSLSSGLQKIFEDPTDSDLHKLKSPSQDNTDSYFRGKTLLLVQQASSQSMTYSEKDERESSLPNGRSVSLMDLQDTHAAQVEHASVMLDVPIRLTGSQLSITQVASIKQLRETQSTPQSAPQVRRPLHPALNQPGGLQPLSFQNPVYHLNNPIPAMPKASIDSSLENLSTASSRSQSNSEDFKLSGPSNSSMEDFTKRSTQSEDFSRRHTVPDRHIPLALPRQNSTGQAQIRKVDQGGLGARAKAPPSLPHSASLRSTGSMSVVSAALVAEPVQNGSRSRQQSSSSRESPVPKVRAIQRQQTQQVQSPVDSATMSPVERTAAWVLNNGQYEEDVEETEQNLDEAKHAEKYEQEITKLKERLRVSSRRLEEYERRLLVQEQQMQKLLLEYKARLEDSEERLRRQQEEKDSQMKSIISRLMAVEEELKKDHAEMQAVIDAKQKIIDAQEKRIVSLDSANTRLMSALTQVKERYSMQVRNGISPTNPTKLSITENGEFKNSSC", "length": 1139 }, "evidence": [ { "id": "SGD:S000001575", "url": "https://alliancegenome.org/gene/SGD:S000001575#orthology", "database": "AGR" }, { "id": "FB:FBgn0261570", "url": "https://alliancegenome.org/gene/FB:FBgn0261570#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A5PF31", "url": "https://www.uniprot.org/uniprotkb/A5PF31" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "A5PF31", "url": "https://www.uniprot.org/uniprotkb/A5PF31" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1176, "end_pos": 1178, "annotation": "n_glycosylation_sequon" }, { "start_pos": 536, "end_pos": 538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 840, "end_pos": 842, "annotation": "n_glycosylation_sequon" }, { "start_pos": 948, "end_pos": 950, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5PF31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PF31" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 192, "end_pos": 310, "start_aa": "Trp", "end_aa": "Tyr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A5PF31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PF31" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 167, "end_pos": 201, "start_aa": "Asp", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "A5PF31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PF31" }, { "id": "PS50018", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50018" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-GAP", "eco_id": "ECO_0000259", "start_pos": 370, "end_pos": 562, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 703, 925 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 103, "end_pos": 105 }, { "start_pos": 1176, "end_pos": 1178 }, { "start_pos": 536, "end_pos": 538 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 840, "end_pos": 842 }, { "start_pos": 948, "end_pos": 950 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A8E7I8-1", "uniprot_ac": "A8E7I8", "uniprot_id": "A8E7I8_DANRE", "mass": { "chemical_mass": 151829.0, "monoisotopic_mass": 151829.0 }, "refseq": { "ac": "NP_001352065", "name": "coiled-coil domain-containing protein 18", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352065" }, "gene_names": [ { "name": "ccdc18", "type": "recommended", "evidence": [ { "id": "A8E7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E7I8" } ] }, { "name": "ccdc18", "type": "synonym", "evidence": [ { "id": "NP_001352065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352065" } ] }, { "name": "fd16d12", "type": "synonym", "evidence": [ { "id": "NP_001352065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352065" }, { "id": "A8E7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E7I8" } ] }, { "name": "si:ch211-132a5.3", "type": "synonym", "evidence": [ { "id": "NP_001352065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352065" }, { "id": "A8E7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E7I8" } ] }, { "name": "si:dkeyp-1a11.3", "type": "synonym", "evidence": [ { "id": "NP_001352065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352065" }, { "id": "A8E7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E7I8" } ] }, { "name": "wu:fd16d12", "type": "synonym", "evidence": [ { "id": "NP_001352065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352065" }, { "id": "A8E7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E7I8" } ] } ], "protein_names": [ { "name": "4.6.1.2", "type": "synonym", "evidence": [ { "id": "A8E7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E7I8/entry#names_and_taxonomy" } ] }, { "name": "Coiled-coil domain-containing protein 18", "type": "synonym", "evidence": [ { "id": "A8E7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E7I8/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 18", "type": "synonym", "evidence": [ { "id": "NP_001352065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352065" } ] }, { "name": "natriuretic peptide receptor B", "type": "synonym", "evidence": [ { "id": "NP_001352065", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352065" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01037827.1, GDQH01032600.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Aug 1, 2018 this sequence version replaced XP_692712.5. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001352065", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352065" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8E7I8", "url": "https://www.uniprot.org/uniprotkb/A8E7I8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ccdc18", "url": "https://www.uniprot.org/uniprotkb/A8E7I8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-5414", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5414", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "564276", "url": "https://www.ncbi.nlm.nih.gov/gene/564276", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:564276", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564276", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A8E7I8", "url": "https://www.orthodb.org/?gene=A8E7I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18875", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18875", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18875:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18875:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR:A8E7I8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A8E7I8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001352065", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352065", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32U0C4", "url": "https://www.uniprot.org/uniprotkb/A0AB32U0C4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U0C4-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32U0C4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0T4", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0T4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0U7", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0U7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0U7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8E7I8", "url": "https://www.uniprot.org/uniprotkb/A8E7I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8E7I8-1", "url": "https://www.uniprot.org/uniprotkb/A8E7I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-5414", "url": "https://zfin.org/ZDB-GENE-030131-5414", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLRDSRGLVEDVVTLRNQLRLTEKNLLSVGEQLSQSGNDIIGEDTDVVEAFPGRLTLEDLQNPDPVDSHPEQQACAHIFDCRSVRDMEAETSVLRRKLNTIRQENASLVLQNRQLMGDIEAAQMELASSRSKIRMLGSTVGARTSSVSHMKEQILGLEAELDTLTKALESAEQRLEVREQTLMQSHRLVEKLRDELRIIKAELADRTRLGKRAEQQRNQALQNAEKLTVTFKEYKEDVAEKLRKVLESEDQLKISLMECDREREELERKCTALESEKENLLHNLCELKEAVSRSESLSTERVQMQSQLQQFSDQIKQLQKELAEKEAQLQDMAGLRRENEDLRLLTACQEQRVAQAHREREQDRAELTSLESVLDLLHLRENREGVLCVNPCLLPALSYTNTTESLRHKPVGERYQKLLAVLQMVEKEKSRQVSAAQSLQERLSRAQEEISSLQNSITERASHYHQLHNQLLEKATQATALEKELKKKNLRVAVLEKQLQEKSSAYSQAVMKTGQLEQDLLEKTSSIQHYQSVLNKKQREYQQTVDKVKLAQSHKCKEMEDEREVLQLSLAQKQTEIEELEQNLTDVHREKQEAQQRATLLQSFIDRLTEDFEAKSKCSEETLRNVEEQAADSASKLRSLQSELSSCKEELSVYLQQMEEIKKHHEKQLEVKSSELSQLQEELRRKCEAYQSSSEENLQLQHSIQNQHCMLEESTSRITQLEESQSLLQSQVSQLEQDLEKERSALSQALRKREREVEEVNQEVQKKERQAAELSGSITQLSSEMSKCRVELSDMELELLRLRRDSNTKASQLVQMEETLKETKGLLDKKSEIVIDLEEKLHRSEMDRRNSLQRAQLLEGQLKEVRGELADTLDHLQELSDVLQHTQLTSDQRQAAIDKLAAELRESQRELEERNHEVLDLDTALKERQGELQQRAQLLGQLDVAIKDHKLEMEKKVEFLQEALEKGQNELREKDQQMQFLTERLEILKSQLQAKEDMDKGAVGHSQQLRVYREQLLKTVQQLQEAQSRCDSLNRQIEEITRQAHQKENEVGQLREELCVMEKRSAQAEVRLQASVSTLQQELEQQREEHRKELSALQQTRGQLLMVSDQISSSLRNSGEQLSQRLQQARDQLEEARSTSARLHAELHNKEQLLQNANENLLIKESEIARLQTKLSSLSRVTDLHNITLRHKPSTPPPPLSPPHKDSIPQDPPSSTRSSLSPWHNTFSDASLELSDSLKASVQAALQPPSSPVQTWQGLTSHEASCSTDMTFNPLTYMLDQEEPEEADLDSLSGMLRFVNQTLALQEQQSLLDNSTHTTGT", "length": 1321, "header": "tr|A8E7I8-1|A8E7I8_DANRE Isoform 1 of Coiled-coil domain-containing protein 18 OS=Danio rerio OX=7955 GN=ccdc18 PE=4 SV=2 CANONICAL=A8E7I8-1" }, "isoforms": [ { "isoform_ac": "A0AB32U0C4-1", "url": "https://www.uniprot.org/uniprotkb/A8E7I8/entry#A0AB32U0C4-1", "sequence": { "sequence": "MEAETSVLRRKLNTIRQENASLVLQNRQLMGDIEAAQMELASSRSKIRMLGSTVGARTSSVSHMKEQILGLEAELDTLTKALESAEQRLEVREQTLMQSHRLVEKLRDELRIIKAELADRTRLGKRAEQQRNQALQNAEKLTVTFKEYKEDVAEKLRKVLESEDQLKISLMECDREREELERKCTALESEKENLLHNLCELKEAVSRSESLSTERVQMQSQLQQFSDQIKQLQKELAEKEAQLQDMAGLRRENEDLRLLTACQEQRVAQAHREREQDRAELTSLESVLDLLHLRENREGVLCVNPCLLPALSYTNTTESLRHKPVGERYQKLLAVLQMVEKEKSRQVSAAQSLQERLSRAQEEISSLQNSITERASHYHQLHNQLLEKATQATALEKELKKKNLRVAVLEKQLQEKSSAYSQAVMKTGQLEQDLLEKTSSIQHYQSVLNKKQREYQQTVDKVKLAQSHKCKEMEDEREVLQLSLAQKQTEIEELEQNLTDVHREKQEAQQRATLLQSFIDRLTEDFEAKSKCSEETLRNVEEQAADSASKLRSLQSELSSCKEELSVYLQQMEEIKKHHEKQLEVKSSELSQLQEELRRKCEAYQSSSEENLQLQHSIQNQHCMLEESTSRITQLEESQSLLQSQVSQLEQDLEKERSALSQALRKREREVEEVNQEVQKKERQAAELSGSITQLSSEMSKCRVELSDMELELLRLRRDSNTKASQLVQMEETLKETKGLLDKKSEIVIDLEEKLHRSEMDRRNSLQRAQLLEGQLKEVRGELADTLDHLQELSDVLQHTQLTSDQRQAAIDKLAAELRESQRELEERNHEVLDLDTALKERQGELQQRAQLLGQLDVAIKDHKLEMEKKVEFLQEALEKGQNELREKDQQMQFLTERLEILKSQLQAKEDMDKGAVGHSQQLRVYREQLLKTVQQLQEAQSRCDSLNRQIEEITRQAHQKENEVGQLREELCVMEKRSAQAEVRLQASVSTLQQELEQQREEHRKELSALQQTRGQLLMVSDQISSSLRNSGEQLSQRLQQARDQLEEARSTSARLHAELHNKEQLLQNANENLLIKESEIARLQTKLSSLSRVTDLHNITLRHKPSTPPPPLSPPHKDSIPQDPPSSTRSSLSPWHNTFSDASLELSDSLKASVQAALQPPSSPVQTWQGLTSHEASCSTDMTFNPLTYMLDQEEPEEADLDSLSGMLRFVNQTLALQEQQSLLDNSTHTTGT", "length": 1235, "header": "tr|A0AB32U0C4-1|A8E7I8_DANRE Computationally mapped isoform of Coiled-coil domain-containing protein 18 OS=Danio rerio OX=7955 GN=ccdc18 PE=4 SV=1 CANONICAL=A8E7I8-1" }, "locus": {} }, { "isoform_ac": "A0AC58H0T4-1", "url": "https://www.uniprot.org/uniprotkb/A8E7I8/entry#A0AC58H0T4-1", "sequence": { "sequence": "MLRDSRGLVEDVVTLRNQLRLTEKNLLSVGEQLSQSGNDIIGEDTDVVEAFPGRLTLEDLQNPDPVDSHPEQQACAHIFDCRSVRDMEAETSVLRRKLNTIRQENASLVLQNRQLMGDIEAAQMELASSRSKIRMLGSTVGARTSSVSHMKEQILGLEAELDTLTKALESAEQRLEVREQTLMQSHRLVEKLRDELRIIKAELADRTRLGKRAEQQRNQALQNAEKLTVTFKEYKEDVAEKLRKVLESEDQLKISLMECDREREELERKCTALESEKENLLHNLCELKEAVSRSESLSTERVQMQSQLQQFSDQIKQLQKELAEKEAQLQDMAGLRRENEDLRLLTACQEQRVAQAHREREQDRAELTSLESVLDLLHLRENREGVLCVNPCLLPALSYTNTTESLRHKPVGERYQKLLAVLQMVEKEKSRQVSAAQSLQERLSRAQEEISSLQNSITERASHYHQLHNQLLEKATQATALEKELKKKNLRVAVLEKQLQEKSSAYSQAVMKTGQLEQDLLEKTSSIQHYQSVLNKKQREYQQTVDKVKLAQSHKCKEMEDEREVLQLSLAQKQTEIEELEQNLTDVHREKQEAQQRATLLQSFIDRLTEDFEAKSKCSEETLRNVEEQAADSASKLRSLQSELSSCKEELSVYLQQMEEIKKHHEKQLEVKSSELSQLQEELRRKCEAYQSSSEENLQLQHSIQNQHCMLEESTSRITQLEESQSLLQSQVSQLEQDLEKERSALSQALRKREREVEEVNQEVQKKERQAAELSGSITQLSSEMSKCRVELSDMELELLRLRRDSNTKASQLVQMEETLKETKGLLDKKSEIVIDLEEKLHRSEMDRRNSLQRAQLLEGQLKEVRGELADTLDHLQELSDVLQHTQLTSDQRQAAIDKLAAELRESQRELEERNHEVLDLDTALKERQGELQQRAQLLGQLDVAIKDHKLEMEKKVEFLQEALEKGQNELREKDQQMQFLTERLEILKSQLQAKEDMDKGAVGHSQQLRVYREQLLKTVQQLQEAQSRCDSLNRQIEEITRQAHQKENEVGQLREELCVMEKRSAQAEVRLQASVSTLQQELEQQREEHRKELSALQQTRGQLLMVSDQISSSLRNSGEQLSQRLQQARDQLEEARSTSARLHAELHNKEQLLQNANENLLIKDPPSSTRSSLSPWHNTFSDASLELSDSLKASVQAALQPPSSPVQTWQGLTSHEASCSTDMTFNPLTYMLDQEEPEEADLDSLSGMLRFVNQTLALQEQQSLLDNSTHTTGT", "length": 1275, "header": "tr|A0AC58H0T4-1|A0AC58H0T4_DANRE Computationally mapped isoform of Coiled-coil domain-containing protein 18 isoform X1 OS=Danio rerio OX=7955 GN=ccdc18 PE=4 SV=1 CANONICAL=A8E7I8-1" }, "locus": {} }, { "isoform_ac": "A0AC58H0U7-1", "url": "https://www.uniprot.org/uniprotkb/A8E7I8/entry#A0AC58H0U7-1", "sequence": { "sequence": "MEAETSVLRRKLNTIRQENASLVLQNRQLMGDIEAAQMELASSRSKIRMLGSTVGARTSSVSHMKEQILGLEAELDTLTKALESAEQRLEVREQTLMQSHRLVEKLRDELRIIKAELADRTRLGKRAEQQRNQALQNAEKLTVTFKEYKEDVAEKLRKVLESEDQLKISLMECDREREELERKCTALESEKENLLHNLCELKEAVSRSESLSTERVQMQSQLQQFSDQIKQLQKELAEKEAQLQDMAGLRRENEDLRLLTACQEQRVAQAHREREQDRAELTSLESVLDLLHLRENREGVLCVNPCLLPALSYTNTTESLRHKPVGERYQKLLAVLQMVEKEKSRQVSAAQSLQERLSRAQEEISSLQNSITERASHYHQLHNQLLEKATQATALEKELKKKNLRVAVLEKQLQEKSSAYSQAVMKTGQLEQDLLEKTSSIQHYQSVLNKKQREYQQTVDKVKLAQSHKCKEMEDEREVLQLSLAQKQTEIEELEQNLTDVHREKQEAQQRATLLQSFIDRLTEDFEAKSKCSEETLRNVEEQAADSASKLRSLQSELSSCKEELSVYLQQMEEIKKHHEKQLEVKSSELSQLQEELRRKCEAYQSSSEENLQLQHSIQNQHCMLEESTSRITQLEESQSLLQSQVSQLEQDLEKERSALSQALRKREREVEEVNQEVQKKERQAAELSGSITQLSSEMSKCRVELSDMELELLRLRRDSNTKASQLVQMEETLKETKGLLDKKSEIVIDLEEKLHRSEMDRRNSLQRAQLLEGQLKEVRGELADTLDHLQELSDVLQHTQLTSDQRQAAIDKLAAELRESQRELEERNHEVLDLDTALKERQGELQQRAQLLGQLDVAIKDHKLEMEKKVEFLQEALEKGQNELREKDQQMQFLTERLEILKSQLQAKEDMDKGAVGHSQQLRVYREQLLKTVQQLQEAQSRCDSLNRQIEEITRQAHQKENEVGQLREELCVMEKRSAQAEVRLQASVSTLQQELEQQREEHRKELSALQQTRGQLLMVSDQISSSLRNSGEQLSQRLQQARDQLEEARSTSARLHAELHNKEQLLQNANENLLIKDPPSSTRSSLSPWHNTFSDASLELSDSLKASVQAALQPPSSPVQTWQGLTSHEASCSTDMTFNPLTYMLDQEEPEEADLDSLSGMLRFVNQTLALQEQQSLLDNSTHTTGT", "length": 1189, "header": "tr|A0AC58H0U7-1|A0AC58H0U7_DANRE Computationally mapped isoform of Coiled-coil domain-containing protein 18 isoform X3 OS=Danio rerio OX=7955 GN=ccdc18 PE=4 SV=1 CANONICAL=A8E7I8-1" }, "locus": {} }, { "isoform_ac": "A8E7I8-1", "url": "https://www.uniprot.org/uniprotkb/A8E7I8/entry#A8E7I8-1", "sequence": { "sequence": "MLRDSRGLVEDVVTLRNQLRLTEKNLLSVGEQLSQSGNDIIGEDTDVVEAFPGRLTLEDLQNPDPVDSHPEQQACAHIFDCRSVRDMEAETSVLRRKLNTIRQENASLVLQNRQLMGDIEAAQMELASSRSKIRMLGSTVGARTSSVSHMKEQILGLEAELDTLTKALESAEQRLEVREQTLMQSHRLVEKLRDELRIIKAELADRTRLGKRAEQQRNQALQNAEKLTVTFKEYKEDVAEKLRKVLESEDQLKISLMECDREREELERKCTALESEKENLLHNLCELKEAVSRSESLSTERVQMQSQLQQFSDQIKQLQKELAEKEAQLQDMAGLRRENEDLRLLTACQEQRVAQAHREREQDRAELTSLESVLDLLHLRENREGVLCVNPCLLPALSYTNTTESLRHKPVGERYQKLLAVLQMVEKEKSRQVSAAQSLQERLSRAQEEISSLQNSITERASHYHQLHNQLLEKATQATALEKELKKKNLRVAVLEKQLQEKSSAYSQAVMKTGQLEQDLLEKTSSIQHYQSVLNKKQREYQQTVDKVKLAQSHKCKEMEDEREVLQLSLAQKQTEIEELEQNLTDVHREKQEAQQRATLLQSFIDRLTEDFEAKSKCSEETLRNVEEQAADSASKLRSLQSELSSCKEELSVYLQQMEEIKKHHEKQLEVKSSELSQLQEELRRKCEAYQSSSEENLQLQHSIQNQHCMLEESTSRITQLEESQSLLQSQVSQLEQDLEKERSALSQALRKREREVEEVNQEVQKKERQAAELSGSITQLSSEMSKCRVELSDMELELLRLRRDSNTKASQLVQMEETLKETKGLLDKKSEIVIDLEEKLHRSEMDRRNSLQRAQLLEGQLKEVRGELADTLDHLQELSDVLQHTQLTSDQRQAAIDKLAAELRESQRELEERNHEVLDLDTALKERQGELQQRAQLLGQLDVAIKDHKLEMEKKVEFLQEALEKGQNELREKDQQMQFLTERLEILKSQLQAKEDMDKGAVGHSQQLRVYREQLLKTVQQLQEAQSRCDSLNRQIEEITRQAHQKENEVGQLREELCVMEKRSAQAEVRLQASVSTLQQELEQQREEHRKELSALQQTRGQLLMVSDQISSSLRNSGEQLSQRLQQARDQLEEARSTSARLHAELHNKEQLLQNANENLLIKESEIARLQTKLSSLSRVTDLHNITLRHKPSTPPPPLSPPHKDSIPQDPPSSTRSSLSPWHNTFSDASLELSDSLKASVQAALQPPSSPVQTWQGLTSHEASCSTDMTFNPLTYMLDQEEPEEADLDSLSGMLRFVNQTLALQEQQSLLDNSTHTTGT", "length": 1321, "header": "tr|A8E7I8-1|A8E7I8_DANRE Isoform 1 of Coiled-coil domain-containing protein 18 OS=Danio rerio OX=7955 GN=ccdc18 PE=4 SV=2 CANONICAL=A8E7I8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A8E7I8", "url": "https://www.uniprot.org/uniprotkb/A8E7I8" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A8E7I8", "url": "https://www.uniprot.org/uniprotkb/A8E7I8" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:564276", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564276", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A9T7-1", "protein_name": "Coiled-coil domain containing 18", "gene_name": "Ccdc18", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESSSSDYYTKDDNEEESLLANVASLRHELKITEWSLHNLGEELSSVSPSDYSDYVCNPSRSERLILEELTQPSHLGCLIYPPYKKVCKTSDRSDYQQKPGDKVPFSSVTMDQEVKNLREKLHKLRQQNAYLVTQNHSLMTKIESVHFELTHSKTKIAMLESTQEQAANIPILEEQIINLEAEVSAQDKVLREAEDKLEQSQKMVIEKEHSLQEAKEECIKLKVDLLEQSKQGKRAERQRNEALYNAEELSKAFQLYKEKVAEKLEKVQVEEEILERNLCNCEKENKRLQEKCNLYKSELEILKEKFRELKEDHYSGKEKLRIMAMKNSEVMSQLTESRQCILKLESELEDKDEILREKFSLINENRELKVRVATQNERLELCQQDIDNSRVELRSLEKLISQMPLKREIVGFKSSLSKHQMNSVSNKDKCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTVNQLSHSIVAYDSRECSRVNTLETEPVKLAESIKDQGQQTVNKQYEREKQRLATGIEELRAKLVQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNASKLENEMTKKCSQLLILEKQLEEKINEYSSIAAKNAELEQELMEKNEKIRSLESNINTEHEKICFAFEKAKKIHLEQHKEMEKQIEQLETQLEKRDQQFKEQEKTMSILQQDILCKQHHLESLDRLLTESKMEMEKENMKKDEALKALQIHVSEETIKVRQLDSALEICKEELALHLNQLEGNKEKFERQLKKKSEEVYCLQKELKIKTHNLEETSEQNAILQHTLQQQQQMLQQETLRSGELEDIQSKLEKQVSKQEQELQKQRESSTEKLRKMEEKYEAAMHDVDLKRQKIVELTGTARQAKLEIDQYKEELSKLEKEITHLKRDGENKSIHLSQLDMILDQTKTELEKKTNSVKELERLQHHTETELTETTQKREALENELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMNQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQAESLNEKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEEYIATQYKEVIDLGQELRLTQEQMQSTHSELVETRRQEVQAQREIERLTGELEDVKQLSREKEAHGNRLAEELGASQVREAHLEARMQAEIKKLSSEVESLKEAYHMEMISHQENHTKWKISADSQKTSVQQLNEQLEKAKQELEEAQDTVSNLHQQVQDRNEVIEAANEALLIKESELTRLQAKISGHEKTGEAKFLTAPFTALTEIVPHVQDPKSAKHPQISLLKCRKLRRSISASDLSFKSHDNDDLSEELLQDLKKMQLEHPSALESDHKDLPVTHSESYKPLPYSLEDDGSESNDFSTLSGMLRYINREVRLLKKPPLQAATGLSQGGKL", "length": 1450 }, "evidence": [ { "id": "HGNC:30370", "url": "https://alliancegenome.org/gene/HGNC:30370#orthology", "database": "AGR" }, { "id": "RGD:1564165", "url": "https://alliancegenome.org/gene/RGD:1564165#orthology", "database": "AGR" }, { "id": "MGI:1922974", "url": "https://alliancegenome.org/gene/MGI:1922974#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5414", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5414#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5T9S5-1", "protein_name": "Coiled-coil domain-containing protein 18", "gene_name": "CCDC18", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESSSSDYYNKDNEEESLLANVASLRHELKITEWSLQSLGEELSSVSPSENSDYAPNPSRSEKLILDVQPSHPGLLNYSPYENVCKISGSSTDFQKKPRDKMFSSSAPVDQEIKSLREKLNKLRQQNACLVTQNHSLMTKFESIHFELTQSRAKVSMLESAQQQAASVPILEEQIINLEAEVSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEALYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTESRQSILKLESELENKDEILRDKFSLMNENRELKVRVAAQNERLDLCQQEIESSRVELRSLEKIISQLPLKRELFGFKSYLSKYQMSSFSNKEDRCIGCCEANKLVISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLETEPVKLGGHQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQLEEKIVAYSSIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAANEALLTKESELTRLQAKISGHEKAEDIKFLPAPFTSPTEIMPDVQDPKFAKCFHTSFSKCTKLRRSISASDLTFKIHGDEDLSEELLQDLKKMQLEQPSTLEESHKNLTYTQPDSFKPLTYNLEADSSENNDFNTLSGMLRYINKEVRLLKKSSMQTGAGLNQGENV", "length": 1454 }, "evidence": [ { "id": "HGNC:30370", "url": "https://alliancegenome.org/gene/HGNC:30370#orthology", "database": "AGR" }, { "id": "RGD:1564165", "url": "https://alliancegenome.org/gene/RGD:1564165#orthology", "database": "AGR" }, { "id": "MGI:1922974", "url": "https://alliancegenome.org/gene/MGI:1922974#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5414", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5414#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q640L5-1", "protein_name": "Coiled-coil domain-containing protein 18", "gene_name": "Ccdc18", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFISSDYCTKDNDNEEESLLANVASLRHELKITEWSLHNLGEELSSVSPSENSEYVCSPSRSERLILEELTQPSHLGRLIYPPYKKVCKTSDSTDYQKKSRDQVSFSSVSMDQEVKNLREKLHKLRQQNACLVTQNHSLMTKIESVHFELTQSKAKIAMLESAQEQAANIPILEEQIINLEAEVSAQDKVLREAEDKLEQSQKMVIEKEHSLQEAKEECIKLKVDLLEQSKQGKRAERQRNEALYNAEELSKAFQLYKEKVAEKLEKVQDEEEILERNLSNCEKENKRLQEKCNLYKSELEILKEKFRELKEEHYSGKEKLMIMAMKNSEVMSQLTESRQCILKLERELEDKDEIVREKFSLLNENRELKVRVATQNERLELCQQDIDNSRVELKSLEKLITQIPLKREIVGFRSSLCKHQRSSVSDKEDKCIGCCEANKLMISELRIKLAIREAEIQKLHANLTVNQLSQNVANDSQECGKVNTLETEPVKLGGSQVESIKDGDQQTVNKQYEREKQRLATGIEELRAKLTQIEAENSDLKVNMAHRTSQFQLIQEELLEKASNASKLENEMTKKCSQLLILEKQLEEKIIAYSSIAAKNAELEQELMEKNEKIRSLESNINTEHEKICFAFEKAKKIHLEQHKEMEKQIEQLETQLEKRDQQFKEQEKTMSILQQDILCKQHHLESLDRLLTESKVEMEKENMKKDEALKALQIHVSEETIKVRQLDSALEICKEELALHLNQLERNKEKFERQLKKKSEEVYCLQKELKIKTHNLEETSEQNAILQHTLQQQQQMLQQETMRNGELEDTQSKLEKQVSKQEQELQKQRESSTEKLRKMEEKYETAIREVDLKRQKIIELTGTARQAKLEMDQYKEELSKMEKEIIHLKRDGENKSMQLSQLDMVLDQTKTELEKTTNSVKELERLQHHTETELTETMQKREALENELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELIEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQVESLNEKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVIKEQEDYIATQYKEVIDLGQELRLTQEQMQNTHSELVEARRQEVQAQREIERLAGELEDIKQLSKEKEAHGNRLAEELGASQVREAHLEARMQAEIKKLSSEVDSLKEAYQIEMISHQENHAKWKLSAESQKTSVQQLNEQLEKAKQELEEAQDTVSNLHQQVQDRNEVIEAANEALLIKESELTRLQAKISGHEKTEDTKYLPAPFTTLTEIIPDSQHPNFAKHSQISLFKCRKLRRSISASDLSFKSHGNDDLSEELLQDLKKMQFEQTSAIESGHKDLPLTHSESFKPLPYNLEDDSSESNDFSTLSGMLRYINKEVRLLKKSSLQTATGLSQGGKL", "length": 1455 }, "evidence": [ { "id": "HGNC:30370", "url": "https://alliancegenome.org/gene/HGNC:30370#orthology", "database": "AGR" }, { "id": "RGD:1564165", "url": "https://alliancegenome.org/gene/RGD:1564165#orthology", "database": "AGR" }, { "id": "MGI:1922974", "url": "https://alliancegenome.org/gene/MGI:1922974#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5414", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5414#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A8E7I8", "url": "https://www.uniprot.org/uniprotkb/A8E7I8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanylate cyclase activity", "id": "GO:0004383", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004383", "evidence": [ { "database": "UniProtKB", "id": "A8E7I8", "url": "https://www.uniprot.org/uniprotkb/A8E7I8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1186, "end_pos": 1188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1300, "end_pos": 1302, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1314, "end_pos": 1316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.6.1.2", "ec_name": "GTP = 3',5'-cyclic GMP + diphosphate.", "evidence": [ { "id": "4.6.1.2", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.6.1.2" }, { "id": "4.6.1.2", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.6.1.2" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 1186, "end_pos": 1188 }, { "start_pos": 1300, "end_pos": 1302 }, { "start_pos": 1314, "end_pos": 1316 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 583, "end_pos": 585 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PKI1-1", "uniprot_ac": "A0A8M9PKI1", "uniprot_id": "A0A8M9PKI1_DANRE", "mass": { "chemical_mass": 65583.0, "monoisotopic_mass": 65583.0 }, "refseq": { "ac": "XP_021331972", "name": "kelch-like protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331972" }, "gene_names": [ { "name": "klhl2", "type": "recommended", "evidence": [ { "id": "A0A8M9PKI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKI1" } ] }, { "name": "klhl2", "type": "synonym", "evidence": [ { "id": "XP_021331972", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331972" } ] } ], "protein_names": [ { "name": "Kelch-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PKI1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKI1/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021331972", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331972" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021331972", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331972" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKI1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKI1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "klhl2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKI1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090312-193", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-193", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd18512", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18512", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "567966", "url": "https://www.ncbi.nlm.nih.gov/gene/567966", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567966", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567966", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RPPACTK", "url": "https://omabrowser.org/oma/group/RPPACTK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PKI1", "url": "https://www.orthodb.org/?gene=A0A8M9PKI1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF155", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF155", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_021331972", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331972", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PKI1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PKI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32THA6", "url": "https://www.uniprot.org/uniprotkb/A0AB32THA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32THA6-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32THA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090312-193", "url": "https://zfin.org/ZDB-GENE-090312-193", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEIHPLCTKLCHHKAVELKDDVYEKQSAVTINPRHMKKAFRIMNELRSQSVLCDVTIIAEDVEIAAHRVVLAAGSPYFHAMFTGEMTESRQKKVRIKEIDGWTLGMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQEVKKACCEFLITQLHPTNCLGIRAFADLHACTELLNLANTYAEQHFSEVVQSEEFLNLGMDQVCSLIASDKLTIPSEEKVFEAVIAWVMHDKDVRQEHLAHLMEHVRLPLLSREYLVQRVEEETLVKNSSACKDYLIEAMKYHLLPADQRSMMKTIRTRVRTPISYPKVMMVVGGQAPKAIRSVECYDFEEERWFQVAELPSRRCRAGVVFMGGVVYAVGGFNGSLRVRTVDAYDPVKDEWCCVSSMQDRRSTLGCAFLSGLLYAVGGFDGSTGLATVEAYNAKANEWFHVNPMNTRRSSVGVGVVGGLLYAVGGYDGATRQCLSTVEAYNPNTNEWSYTAEMGTRRSGAGVGVLKGLLYAVGGHDGPLVRKSCEVFDPATNTWKQVADMNMCRRNAGVCALSNLLYVIGGDDGSCNLASVEFYNPNTDKWTLLPTCMSTGRSYAGVTVIDKPL", "length": 590, "header": "tr|A0A8M9PKI1-1|A0A8M9PKI1_DANRE Isoform 1 of Kelch-like protein 2 isoform X1 OS=Danio rerio OX=7955 GN=klhl2 PE=4 SV=1 CANONICAL=A0A8M9PKI1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PKI1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKI1/entry#A0A8M9PKI1-1", "sequence": { "sequence": "MEIHPLCTKLCHHKAVELKDDVYEKQSAVTINPRHMKKAFRIMNELRSQSVLCDVTIIAEDVEIAAHRVVLAAGSPYFHAMFTGEMTESRQKKVRIKEIDGWTLGMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQEVKKACCEFLITQLHPTNCLGIRAFADLHACTELLNLANTYAEQHFSEVVQSEEFLNLGMDQVCSLIASDKLTIPSEEKVFEAVIAWVMHDKDVRQEHLAHLMEHVRLPLLSREYLVQRVEEETLVKNSSACKDYLIEAMKYHLLPADQRSMMKTIRTRVRTPISYPKVMMVVGGQAPKAIRSVECYDFEEERWFQVAELPSRRCRAGVVFMGGVVYAVGGFNGSLRVRTVDAYDPVKDEWCCVSSMQDRRSTLGCAFLSGLLYAVGGFDGSTGLATVEAYNAKANEWFHVNPMNTRRSSVGVGVVGGLLYAVGGYDGATRQCLSTVEAYNPNTNEWSYTAEMGTRRSGAGVGVLKGLLYAVGGHDGPLVRKSCEVFDPATNTWKQVADMNMCRRNAGVCALSNLLYVIGGDDGSCNLASVEFYNPNTDKWTLLPTCMSTGRSYAGVTVIDKPL", "length": 590, "header": "tr|A0A8M9PKI1-1|A0A8M9PKI1_DANRE Isoform 1 of Kelch-like protein 2 isoform X1 OS=Danio rerio OX=7955 GN=klhl2 PE=4 SV=1 CANONICAL=A0A8M9PKI1-1" }, "locus": {} }, { "isoform_ac": "A0AB32THA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKI1/entry#A0AB32THA6-1", "sequence": { "sequence": "MEIHPLQSVLCDVTIIAEDVEIAAHRVVLAAGSPYFHAMFTGEMTESRQKKVRIKEIDGWTLGMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQEVKKACCEFLITQLHPTNCLGIRAFADLHACTELLNLANTYAEQHFSEVVQSEEFLNLGMDQVCSLIASDKLTIPSEEKVFEAVIAWVMHDKDVRQEHLAHLMEHVRLPLLSREYLVQRVEEETLVKNSSACKDYLIEAMKYHLLPADQRSMMKTIRTRVRTPISYPKVMMVVGGQAPKAIRSVECYDFEEERWFQVAELPSRRCRAGVVFMGGVVYAVGGFNGSLRVRTVDAYDPVKDEWCCVSSMQDRRSTLGCAFLSGLLYAVGGFDGSTGLATVEAYNAKANEWFHVNPMNTRRSSVGVGVVGGLLYAVGGYDGATRQCLSTVEAYNPNTNEWSYTAEMGTRRSGAGVGVLKGLLYAVGGHDGPLVRKSCEVFDPATNTWKQVADMNMCRRNAGVCALSNLLYVIGGDDGSCNLASVEFYNPNTDKWTLLPTCMSTGRSYAGVTVIDKPL", "length": 548, "header": "tr|A0AB32THA6-1|A0A8M9PKI1_DANRE Computationally mapped isoform of Kelch-like protein 2 isoform X1 OS=Danio rerio OX=7955 GN=klhl2 PE=4 SV=1 CANONICAL=A0A8M9PKI1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:567966", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567966", "resource": "KEGG Pathway" }, { "id": "R-DRE-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-DRE-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LWA6-1", "protein_name": "Kelch like family member 2", "gene_name": "KLHL2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "METPPRPPACTNQGHQKSLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAEQHFADVVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKDVRQEFMARLMEHVRLPLLPREYLVQRVEEEALVKNSSACKDYLIEAMKYHLLPTEQRILMKSIRTRLRTPMNLPKLMVVVGGQAPKAIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNGSLRVRTVDSYDPVKDQWTSVANMRDRRSTLGAAVLNGLLYAVGGFDGSTGLSSVEAYNIKSNEWFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYSATANEWTYIAEMSTRRSGAGVGVLNNLLYAVGGHDGPLVRKSVEVYDPATNTWRQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPTTDKWTVVSSCMSTGRSYAGVTVIDKPL", "length": 593 }, "evidence": [ { "id": "A0A8M9PKI1", "url": "https://omabrowser.org/oma/group/A0A8M9PKI1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E0CZ16-1", "protein_name": "Kelch-like protein 3", "gene_name": "Klhl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGESVKPSPQPTAQAEDEEKNRRTVTVNAAHMGKAFKVMNELRSKRLLCDVMIVAEDVEVEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLDHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEGRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGVAVIHKSL", "length": 587 }, "evidence": [ { "id": "FB:FBgn0001301", "url": "https://alliancegenome.org/gene/FB:FBgn0001301#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E7F6F9-1", "protein_name": "Kelch-like protein 3", "gene_name": "klhl3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLWGFFLRFRFFLTCGRNCIQKTLDSQDDAKDPGLHTFSHTHMRKAFLLMNDLRSHSRKMLCDVLLVAGEVEIPAHRVVLASCSPYFCAMFTGDMSESKANHVEIRDVDGQTLLKLVDYIYSAEIEVSEENVQVLLPAASLLQLMDVRQVCCDFLQTQLHPTNCLGIRAFADLHACTVLLSQAHAYAAEQHFTDVMVGEEFMALSLQQVCSLISSDKLTVSTEEKVFEAMVAWIKHDKEARLEHMPKLMEHVRLPLLSRDYLVQIVEEEPLIKNNNTCKDFLIEAMKYHLLPADQRHLIKTDRTRPRTPISLPKVMMVVGGQAPKAIRSVECYDFQEDRWYQVADLPSRRCRAGVVYMAGKVYAVGGFNGSLRVRTVDVYDGLKDQWSSIPSMQERRSTLGAAVLGDLLYAVGGFDGSTGLSSVEAYNPKANEWMFVAPMNTRRSSVGVGVVDGKLYAVGGYDGASRQCLSTVEEFNPVSNKWCYVSDMSTRRSGAGVGVLSGQLYAAGGHDGPLVRKSVEVYDPTTNTWRQVCDMNMCRRNAGVCAINGLLYVIGGDDGSCNLSSVEYYDPAADKWSLIPTNMSNGRSYAGVSVIDKPL", "length": 601 }, "evidence": [ { "id": "FB:FBgn0001301", "url": "https://alliancegenome.org/gene/FB:FBgn0001301#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LZ52-1", "protein_name": "Kelch-like protein 3", "gene_name": "Klhl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGESVKPSPQPTEQAGDGEKNRRMITVNPAHMGKAFKVMNELRSKRLLCDVMIVAEDVEVEAHRVVLAACSPYFCAMFTGDMSESKAKKIEIKDVDGQTLSKLIDYIYTAEIEVTEENVQVLLPAASLLQLMDVRQNCCDFLQSQLHPTNCLGIRAFADVHTCTDLLQQANAYAEQHFPEVMLGEEFLSLSLDQVCSLISSDKLTVSSEEKVFEAVISWINYEKETRLDHMAKLMEHVRLPLLPRDYLVQTVEEEALIKNNNTCKDFLIEAMKYHLLPLDQRLLIKNPRTKPRTPVSLPKVMIVVGGQAPKAIRSVECYDFEEGRWDQIAELPSRRCRAGVVFMAGHVYAVGGFNGSLRVRTVDVYDGVKDQWTSIASMQERRSTLGAAVLNDLLYAVGGFDGSTGLASVEAYSYKTNEWFFVAPMNTRRSSVGVGVVEGKLYAVGGYDGASRQCLSTVEQYNPATNEWIYVADMSTRRSGAGVGVLSGQLYATGGHDGPLVRKSVEVYDPGTNTWKQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPVTDKWTLLPTNMSTGRSYAGQWVSASGA", "length": 587 }, "evidence": [ { "id": "FB:FBgn0001301", "url": "https://alliancegenome.org/gene/FB:FBgn0001301#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LZF0-1", "protein_name": "Kelch-like protein 2", "gene_name": "Klhl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESPPLPPACTKQGHQKPLDSKDENPEKHCPLTVNPWHMKKAFKVMNELRSQNLLCDVTIVAEDMEIPAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAEQHFADVVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKDVRQEFMARLMEHVRLPLLPREYLVQRVEEEALVKNSSACKDYLIEAMKYHLLPTEQRMLMKSVRTRLRTPMNLPKLMVVVGGQAPKAIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNGSLRVRTVDSYDPVKDQWTSVANMRDRRSTLGAAVLNGLLYAVGGFDGSTGLSSVEAYNIKSNEWFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYNATANEWTYIAEMSTRRSGAGVGVLNNLLYAVGGHDGPLVRKSVEVYDPTTNAWRQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPTTDKWTVVSSCMSTGRSYAGVTVIDKPL", "length": 593 }, "evidence": [ { "id": "RGD:1306388", "url": "https://alliancegenome.org/gene/RGD:1306388#orthology", "database": "AGR" }, { "id": "HGNC:6353", "url": "https://alliancegenome.org/gene/HGNC:6353#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-193", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-193#orthology", "database": "AGR" }, { "id": "MGI:1924363", "url": "https://alliancegenome.org/gene/MGI:1924363#orthology", "database": "AGR" }, { "id": "FB:FBgn0001301", "url": "https://alliancegenome.org/gene/FB:FBgn0001301#orthology", "database": "AGR" }, { "id": "A0A8M9PKI1", "url": "https://omabrowser.org/oma/group/A0A8M9PKI1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1RWC7-1", "protein_name": "Kelch like family member 2", "gene_name": "KLHL2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "METPPRPPACTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAEQHFADVVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKDVRQEFMARLMEHVRLPLLPREYLVQRVEEEALVKNSSACKDYLIEAMKYHLLPTEQRILMKSVRTRLRTPMNLPKLMVVVGGQAPKAIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNGSLRVRTVDSYDPVKDQWTSVANMRDRRSTLGAAVLNGLLYAVGGFDGSTGLSSVEAYNIKSNEWFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYNATANEWTYIAEMSTRRSGAGVGVLNNLLYAVGGHDGPLVRKSVEVYDPASNTWRQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPTTDKWTVVSSCMSTGRSYAGVTVIDKPL", "length": 593 }, "evidence": [ { "id": "A0A8M9PKI1", "url": "https://omabrowser.org/oma/group/A0A8M9PKI1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O95198-1", "protein_name": "Kelch-like protein 2", "gene_name": "KLHL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "METPPLPPACTKQGHQKPLDSKDDNTEKHCPVTVNPWHMKKAFKVMNELRSQNLLCDVTIVAEDMEISAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLIDYVYTAEIQVTEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAEQHFADVVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKDVRQEFMARLMEHVRLPLLPREYLVQRVEEEALVKNSSACKDYLIEAMKYHLLPTEQRILMKSVRTRLRTPMNLPKLMVVVGGQAPKAIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNGSLRVRTVDSYDPVKDQWTSVANMRDRRSTLGAAVLNGLLYAVGGFDGSTGLSSVEAYNIKSNEWFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYNATTNEWTYIAEMSTRRSGAGVGVLNNLLYAVGGHDGPLVRKSVEVYDPTTNAWRQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPTTDKWTVVSSCMSTGRSYAGVTVIDKPL", "length": 593 }, "evidence": [ { "id": "RGD:1306388", "url": "https://alliancegenome.org/gene/RGD:1306388#orthology", "database": "AGR" }, { "id": "HGNC:6353", "url": "https://alliancegenome.org/gene/HGNC:6353#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-193", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-193#orthology", "database": "AGR" }, { "id": "MGI:1924363", "url": "https://alliancegenome.org/gene/MGI:1924363#orthology", "database": "AGR" }, { "id": "FB:FBgn0001301", "url": "https://alliancegenome.org/gene/FB:FBgn0001301#orthology", "database": "AGR" }, { "id": "A0A8M9PKI1", "url": "https://omabrowser.org/oma/group/A0A8M9PKI1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q04652-1", "protein_name": "Ring canal kelch protein", "gene_name": "kel", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIALSALLTKYTIGIMSNLSNGNSNNNNQQQQQQQQGQNPQQPAQNEGGAGAEFVAPPPGLGAAVGVAAMQQRNRLLQQQQQQHHHHQNPAAEGSGLERGSCLLRYASQNSLDESSQKHVQRPNGKERGTVGQYSNEQHTARSFDAMNEMRKQKQLCDVILVADDVEIHAHRMVLASCSPYFYAMFTSFEESRQARITLQSVDARALELLIDYVYTATVEVNEDNVQVLLTAANLLQLTDVRDACCDFLQTQLDASNCLGIREFADIHACVELLNYAETYIEQHFNEVIQFDEFLNLSHEQVISLIGNDRISVPNEERVYECVIAWLRYDVPMREQFTSLLMEHVRLPFLSKEYITQRVDKEILLEGNIVCKNLIIEALTYHLLPTETKSARTVPRKPVGMPKILLVIGGQAPKAIRSVEWYDLREEKWYQAAEMPNRRCRSGLSVLGDKVYAVGGFNGSLRVRTVDVYDPATDQWANCSNMEARRSTLGVAVLNGCIYAVGGFDGTTGLSSAEMYDPKTDIWRFIASMSTRRSSVGVGVVHGLLYAVGGYDGFTRQCLSSVERYNPDTDTWVNVAEMSSRRSGAGVGVLNNILYAVGGHDGPMVRRSVEAYDCETNSWRSVADMSYCRRNAGVVAHDGLLYVVGGDDGTSNLASVEVYCPDSDSWRILPALMTIGRSYAGVCMIDKPMXMEEQGALARQAASLAIALLDDENSQAEGTMEGAIGGAIYGNLAPAGGAAAAAAPAAPAQAPQPNHPHYENIYAPIGQPSNNNNNSGSNSNQAAAIANANAPANAEEIQQQQQPAPTEPNANNNPQPPTAAAPAPSQQQQQQQAQPQQPQRILPMNNYRNDLYDRSAAGGVCSAYDVPRAVRSGLGYRRNFRIDMQNGNRCGSGLRCTPLYTNSRSNCQRQRSFDDTESTDGYNLPYAGAGTMRYENIYEQIRDEPLYRTSAANRVPLYTRLDVLGHGIGRIERHLSSSCGNIDHYNLGGHYAVLGHSHFGTVGHIRLNANGSGVAAPGVAGTGTCNVPNCQGYMTAAGSTVPVEYANVKVPVKNSASSFFSCLHGENSQSMTNIYKTSGTAAAMAAHNSPLTPNVSMERASRSASAGAAGSAAAAVEEHSAADSIPSSSNINANRTTGAIPKVKTANKPAKESGGSSTAASPILDKTTSTGSGKSVTLAKKTSTAAARSSSSGDTNGNGTLNRISKSSLQWLLVNKWLPLWIGQGPDCKVIDFNFMFSRDCVSCDTASVASQMSNPYGTPRLSGLPQDMVRFQSSCAGACAAAGAASTIRRDANASARPLHSTLSRLRNGEKRNPNRVAGNYQYEDPSYENVHVQWQNGFEFGRSRDYDPNSTYHQQRPLLQRARSESPTFSNQQRRLQRQGAQAQQQSQQPKPPGSPDPYKNYKLNADNNTFKPKPIAADELEGAVGGAVAEIALPEVDIEVVDPVSLSDNETETTSSQNNLPSTTNSNNLNEHND", "length": 1477 }, "evidence": [ { "id": "RGD:1306388", "url": "https://alliancegenome.org/gene/RGD:1306388#orthology", "database": "AGR" }, { "id": "HGNC:6353", "url": "https://alliancegenome.org/gene/HGNC:6353#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-193", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-193#orthology", "database": "AGR" }, { "id": "MGI:1924363", "url": "https://alliancegenome.org/gene/MGI:1924363#orthology", "database": "AGR" }, { "id": "FB:FBgn0001301", "url": "https://alliancegenome.org/gene/FB:FBgn0001301#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8JZP3-1", "protein_name": "Kelch-like protein 2", "gene_name": "Klhl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METPPLPPACTKQGHQKPLDSKDENPEKHCPLTVNPWHMKKAFKVMNELRSQNLLCDVTIVAEDMEIPAHRVVLAACSPYFHAMFTGEMSESRAKRVRIKEVDGWTLRMLVDYVYTAEIQVTEENVQVLLPAAGLLQLQDVKKTCCEFLESQLHPVNCLGIRAFADMHACTDLLNKANTYAEQHFADVVLSEEFLNLGIEQVCSLISSDKLTISSEEKVFEAVIAWVNHDKDVRQEFMARLMEHVRLPLLPREYLVQRVEEEALVKNSSACKDYLIEAMKYHLLPTEQRMLMKSVRTRLRTPMNLPKLMVVVGGQAPKAIRSVECYDFKEERWHQVAELPSRRCRAGMVYMAGLVFAVGGFNGSLRVRTVDSYDPVKDQWTSVANMRDRRSTLGAAVLNGLLYAVGGFDGSTGLSSVEAYNIKSNEWFHVAPMNTRRSSVGVGVVGGLLYAVGGYDGASRQCLSTVECYNATANEWTYIAEMSTRRSGAGVGVLNNLLYAVGGHDGPLVRKSVEVYDPTTNAWRQVADMNMCRRNAGVCAVNGLLYVVGGDDGSCNLASVEYYNPTTDKWTVVSSCMSTGRSYAGVTVIDKPL", "length": 593 }, "evidence": [ { "id": "RGD:1306388", "url": "https://alliancegenome.org/gene/RGD:1306388#orthology", "database": "AGR" }, { "id": "HGNC:6353", "url": "https://alliancegenome.org/gene/HGNC:6353#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-193", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-193#orthology", "database": "AGR" }, { "id": "MGI:1924363", "url": "https://alliancegenome.org/gene/MGI:1924363#orthology", "database": "AGR" }, { "id": "FB:FBgn0001301", "url": "https://alliancegenome.org/gene/FB:FBgn0001301#orthology", "database": "AGR" }, { "id": "A0A8M9PKI1", "url": "https://omabrowser.org/oma/group/A0A8M9PKI1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UH77-1", "protein_name": "Kelch-like protein 3", "gene_name": "KLHL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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{ "database": "UniProtKB", "id": "A0A8M9PKI1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKI1" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKI1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKI1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKI1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKI1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKI1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKI1" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": 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{ "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PNC7-1", "uniprot_ac": "A0A8M9PNC7", "uniprot_id": "A0A8M9PNC7_DANRE", "mass": { "chemical_mass": 392222.0, "monoisotopic_mass": 392222.0 }, "refseq": { "ac": "XP_021322705", "name": "CUB and sushi domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322705" }, "gene_names": [ { "name": "csmd3a", "type": "recommended", "evidence": [ { "id": "A0A8M9PNC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNC7" } ] }, { "name": "csmd3a", "type": "synonym", "evidence": [ { "id": "XP_021322705", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322705" } ] } ], "protein_names": [ { "name": "CUB and sushi domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322705", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322705" }, { "id": "A0A8M9PNC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNC7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322705", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322705" } ] } ], "disease": [ { "disease_id": "DOID:5419", "recommended_name": { "id": "DOID:5419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5419", "name": "schizophrenia", "description": "A psychotic disorder that is characterized by a disintegration of thought processes and of emotional responsiveness." }, "synonyms": [ { "id": "DOID:5419", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5419", "name": "schizophrenia-1", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "A major psychotic disorder characterized by abnormalities in the perception or expression of reality. It affects the cognitive and psychomotor functions. Common clinical signs and symptoms include delusions, hallucinations, disorganized thinking, and retreat from reality." }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia 12", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "schizophrenia (disease)", "description": "" }, { "id": "MONDO:0005090", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005090", "name": "SCZD", "description": "" }, { "id": "MIM:181500", "resource": "MIM", "url": "https://www.omim.org/entry/181500", "name": "Schizophrenia", "description": "Schizophrenia" } ], "unlinked_id_list": [], "evidence": [ { "id": "5419", "database": "AGR", "url": 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Classification", "Other" ] }, { "id": "XP_021322705", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322705", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PNC7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PNC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T3A2", "url": "https://www.uniprot.org/uniprotkb/A0AB32T3A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T3A2-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T3A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TAA2", "url": "https://www.uniprot.org/uniprotkb/A0AB32TAA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TAA2-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TAA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLH7", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLH7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLH7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLH7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLI3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLI3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLI3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLI3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050419-118", "url": "https://zfin.org/ZDB-GENE-050419-118", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKAADNEGWRGFLVLSHRGCIRCAHGTTMTIKTGFIIGNIVFCCILTCVQGFIYTCGGTLKGKNGTIESPGFPHGYPNGANCTWVIVAEERSRIHIVFQSFAVEEEYDFLSLYDGHPHPANFRTRLTGFQVPAPVTSTGSIFSLRLTSDFAVSAHGFKIYYEELQSSSCGNPGIPAKGILNGSSFNVGDRIRYHCVSGYTLDGHAQLTCVTSTSNVAVWDFPIPICRAEDTCGGTFRGASGTISSPDFQKDYQSSGECTWTILADPGDTISLVFTEFQMDSKLDSLEVEGSDPPTIWLSGINIPVPIVSNKNWLRLHFVTDNSHRHKGFSAQYQVKRSGDFKSRGVKLLPGKDNTSKFSIMNEGMVKQVSNFCPDPGEPENGKRIGTDYSIGATVQFTCDGDHVLQGSKSITCQRVAEVFAAWSDHRPVCKVKTCGMNLLGPSGTFTSPNFPIQYESNSQCVWIITASNPNKVIQINFEEFDLELGYDTLTVGDGGEVGDSKTIIQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGIPLYGLREGGGFSNGGVLRFECQFGFELIGERMISCQNNNQWSANIPICIFPCMSNFTAAMGTVLSPDYPEGYGNNLNCVWLIIAEAGSRIHLAFNDFDLEPPYDFLTVRDGDLADAVVLGRFSGAEVPSHLTSNSNILQLEFQADHSMSGRGFNITYSTFGHNECPDPGVPMNAKRFGNNFQLGSSISVVCEEGFIKTQGSDTIVCELEAGKVMWSGLIPKCEAPCGGHFTAPVGVILSPGWPGYYKDSLSCEWVIEAETGRSIKISFDRFQTELNYDFLEVHDGPNLLSPLIASLNGTQVPQFLFSSSNFLYLLFTTDNSRSNSGFKLFYESVTLDTHSCLDPGVPVNGVRYGQDLAIGSVVWFGCEPGYRLSHEEQLVCEKNHWWSHPLPTCDALCGGDVRGPEGIILSPGFPELYPNSLNCTWTLEVSHGKGVQFTFHAFHLEDHHDYLLLTENGSFVRPLARLTGSQRPPPVNAGLYGNFKAQLRFISDFSISFQGFNISFSEYDLEPCEDPGVPQFGRHSGGSFGIGDTLAFSCDPGYRLQGVPQISCLGGGRRIWSAPLPRCVAECGSTVSKNAGVLLSPNYPRNYDNNHECIYNIQVQAGKGINISASSFHLAQGDVLKLYDGPDNTADVLGAFSGSSMLSQSLTSTSNHLWLEFYSDQEDTAEGFKLAYTSFELSHCDEPGVPQFGSKVSDQGHFAGSVVTYHCDPGYSLHGSSILRCMTGERRTWDHPLPSCIAECGGSFKGESSGRILSPGYPFPYDNNLRCTWTIEVDSGNTVSLQFLAFDTEASHDILKVWDGHPENEMALKEVSGSLLPDGIHSTLNVVTIQFETDFYISKSGFAIDFSSSVATACRDPGTPMNGSRSGEGKEPGDTMTFACDPGYDLQGEPRITCIQVDNRFYWQPSPPTCIAPCGGNITGSSGFILSPNFPHPYPHSKDCDWFITVHPDYVISLAFISFSIEPNYDFLYIYDGPHSNSHLIGTFQDSKLPEKVESSSNIMHIAFRSDGSVSYTGFHLEYKAKLREACFDPGSVMNGTRLGGDYKLGSTVTFHCDPGYQLQGYSSLTCVMGATNRPEWNRALPSCQAPCGSRSTGSEGTILSPNYPRNYTTGQSCVYEISVPGEFVLFGQFMFFQTTSNDVVEIFDGASTESALLSSTYGSHSGEPLPLSSANEITIRFKTEGPNTAKGFHFVYQAVPRTSASQCSSVPEPRYGKRIGNDFGLGTVVLFECNPGYTLHGASAIRCEAVPNSLAQWNGTVPACVVACGGVLTTRRGTILSPGYPDPYDNHLNCVWKVFVPEGTGIQITVVTFSTEHNWDSLDFYDGIDSNAPRLGSYSGTTIPPLLNTTSNNLYLTFQTDMSVSGAGFHLEYTAIGLDSCPEPQTPGNGVKVGDRYFVGDVVSFHCEQGYTLKGSAYITCMPGPVRRWNYPAPLCLAQCGGFLTDLNGVILSPGFPGNYPSGLDCNWTVKLPIGFGIHLQFLNFSTESVHDYLEVRSGTLDSGSVIDRFSGPVVPESFFSTTHETSFFFHSDYSQNKPGFHITYEAYELQRCPDPRPFRNGVVIGSDFGVGMTISFQCLPGYTLLGESSLTCLHGVSRNWNHPVPRCEALCGGNITVLNGTIYSPGHPADYPNLKDCIWSIRVPPGNGIHINFTVLNTEPIYDYITIWDGPDQTSPQIGQFSGSLPQEPVSSTSNHILLKFHSDFSTSGFFVLRYHAYQLRVCQPPPPVANAEILAEDDEFQIGDIIRYRCLPGFTLLGSEILTCRLGERLQMDGPPPVCQVQCPDNEVLFDSTGVILSPGYPDSYPNLQMCSWMINVEKGYNITLHFQLFQTEKEFDILEIFDGPNIYSQSLAVLSGDLSVPFNITTTGHQLFLRWSSDHGTNKKGFRITYVGEYQTMYCSTPDSPQHGFVLSQTGGHVNSVVRWACDRGFRLIGKNMAVCKRTEIGFLAWDSSVPACQAVSCGMPVAPVNGGVLAADYSAGTRATYFCNDGFRLSSKEVTSTVCQADGTWSSHNKIPRCTVVVCPSIGSFTLDHGKWRIVNGSRYEYGTKVAFTCNAGYYRLGPAHIHCTSNGTWSWRNERPRCKVISCGELPTPPNGKKIGTQTTFGATAIFTCNSGFILVGSTVRECLPSGLWSGTETHCLAGHCGIPERIVNGQVIGENFGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVSISCGHPGSPIYGRTVGDGFNLNDVVTFFCNKGYILEGPSEAQCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYLFGSSVLTCQPVGYWDKPLPECLEVDCGHPGSPPHAVVTGDKFTFGSTVHYRCLEDRVLIGESTRACQLNGQWGGSQPHCSGDKRGACGDPGTPAHATREESSFQQHAKVRFTCSTGHTLYGSAERICFPNGTWSGRQPTCKPVQCGNPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPTRQCLANGTWSGGEPNCTLISCGDSGVPASGLRTGEDFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSCQAVTCSPPPAVSNGEVEGSVFEWGVSVSYRCMMGYELSFPAVLTCAGNGSWSGEIPLCLPKFCGDPGIPSRARREGQSFIFKAEVMFSCSAPYVLVGSSTRTCQADATWSGTQPRCIEPTRTTCENPGTPEFGSLNSSLGFKVGSTVKFVCQTGHLLLGSTTRTCQQDLTWSGSQPECIPHSCKQPKTPPHANVLGMDLPSFGYTLLYSCQPGFILTGGSEHRACRPDGSWTGKVPVCRAGSKTSEKVITPVQGTSSPKVNVPDDVFAPTFLWKGSFEYKGAKQPMTLTITSFNATTGKVNATLTNRHSELLLSGVYKSRDARLTLRLYHMKTLLKNTYSKTTEESMIMDGFVSADHEGNTYLFQGFIQGRDYGPFGLQRQGLNVLEPTRSPEIPPRTNSSSVAIAILVPFFALIFAGFGFYLYKQRKSDKAEYSGCSVHENNNGQATFENPMYNTNSKSIEGKVVRFDPNLNTVCTMV", "length": 3598, "header": "tr|A0A8M9PNC7-1|A0A8M9PNC7_DANRE Isoform 1 of CUB and sushi domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=csmd3a PE=3 SV=1 CANONICAL=A0A8M9PNC7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PNC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNC7/entry#A0A8M9PNC7-1", "sequence": { "sequence": "MKAADNEGWRGFLVLSHRGCIRCAHGTTMTIKTGFIIGNIVFCCILTCVQGFIYTCGGTLKGKNGTIESPGFPHGYPNGANCTWVIVAEERSRIHIVFQSFAVEEEYDFLSLYDGHPHPANFRTRLTGFQVPAPVTSTGSIFSLRLTSDFAVSAHGFKIYYEELQSSSCGNPGIPAKGILNGSSFNVGDRIRYHCVSGYTLDGHAQLTCVTSTSNVAVWDFPIPICRAEDTCGGTFRGASGTISSPDFQKDYQSSGECTWTILADPGDTISLVFTEFQMDSKLDSLEVEGSDPPTIWLSGINIPVPIVSNKNWLRLHFVTDNSHRHKGFSAQYQVKRSGDFKSRGVKLLPGKDNTSKFSIMNEGMVKQVSNFCPDPGEPENGKRIGTDYSIGATVQFTCDGDHVLQGSKSITCQRVAEVFAAWSDHRPVCKVKTCGMNLLGPSGTFTSPNFPIQYESNSQCVWIITASNPNKVIQINFEEFDLELGYDTLTVGDGGEVGDSKTIIQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGIPLYGLREGGGFSNGGVLRFECQFGFELIGERMISCQNNNQWSANIPICIFPCMSNFTAAMGTVLSPDYPEGYGNNLNCVWLIIAEAGSRIHLAFNDFDLEPPYDFLTVRDGDLADAVVLGRFSGAEVPSHLTSNSNILQLEFQADHSMSGRGFNITYSTFGHNECPDPGVPMNAKRFGNNFQLGSSISVVCEEGFIKTQGSDTIVCELEAGKVMWSGLIPKCEAPCGGHFTAPVGVILSPGWPGYYKDSLSCEWVIEAETGRSIKISFDRFQTELNYDFLEVHDGPNLLSPLIASLNGTQVPQFLFSSSNFLYLLFTTDNSRSNSGFKLFYESVTLDTHSCLDPGVPVNGVRYGQDLAIGSVVWFGCEPGYRLSHEEQLVCEKNHWWSHPLPTCDALCGGDVRGPEGIILSPGFPELYPNSLNCTWTLEVSHGKGVQFTFHAFHLEDHHDYLLLTENGSFVRPLARLTGSQRPPPVNAGLYGNFKAQLRFISDFSISFQGFNISFSEYDLEPCEDPGVPQFGRHSGGSFGIGDTLAFSCDPGYRLQGVPQISCLGGGRRIWSAPLPRCVAECGSTVSKNAGVLLSPNYPRNYDNNHECIYNIQVQAGKGINISASSFHLAQGDVLKLYDGPDNTADVLGAFSGSSMLSQSLTSTSNHLWLEFYSDQEDTAEGFKLAYTSFELSHCDEPGVPQFGSKVSDQGHFAGSVVTYHCDPGYSLHGSSILRCMTGERRTWDHPLPSCIAECGGSFKGESSGRILSPGYPFPYDNNLRCTWTIEVDSGNTVSLQFLAFDTEASHDILKVWDGHPENEMALKEVSGSLLPDGIHSTLNVVTIQFETDFYISKSGFAIDFSSSVATACRDPGTPMNGSRSGEGKEPGDTMTFACDPGYDLQGEPRITCIQVDNRFYWQPSPPTCIAPCGGNITGSSGFILSPNFPHPYPHSKDCDWFITVHPDYVISLAFISFSIEPNYDFLYIYDGPHSNSHLIGTFQDSKLPEKVESSSNIMHIAFRSDGSVSYTGFHLEYKAKLREACFDPGSVMNGTRLGGDYKLGSTVTFHCDPGYQLQGYSSLTCVMGATNRPEWNRALPSCQAPCGSRSTGSEGTILSPNYPRNYTTGQSCVYEISVPGEFVLFGQFMFFQTTSNDVVEIFDGASTESALLSSTYGSHSGEPLPLSSANEITIRFKTEGPNTAKGFHFVYQAVPRTSASQCSSVPEPRYGKRIGNDFGLGTVVLFECNPGYTLHGASAIRCEAVPNSLAQWNGTVPACVVACGGVLTTRRGTILSPGYPDPYDNHLNCVWKVFVPEGTGIQITVVTFSTEHNWDSLDFYDGIDSNAPRLGSYSGTTIPPLLNTTSNNLYLTFQTDMSVSGAGFHLEYTAIGLDSCPEPQTPGNGVKVGDRYFVGDVVSFHCEQGYTLKGSAYITCMPGPVRRWNYPAPLCLAQCGGFLTDLNGVILSPGFPGNYPSGLDCNWTVKLPIGFGIHLQFLNFSTESVHDYLEVRSGTLDSGSVIDRFSGPVVPESFFSTTHETSFFFHSDYSQNKPGFHITYEAYELQRCPDPRPFRNGVVIGSDFGVGMTISFQCLPGYTLLGESSLTCLHGVSRNWNHPVPRCEALCGGNITVLNGTIYSPGHPADYPNLKDCIWSIRVPPGNGIHINFTVLNTEPIYDYITIWDGPDQTSPQIGQFSGSLPQEPVSSTSNHILLKFHSDFSTSGFFVLRYHAYQLRVCQPPPPVANAEILAEDDEFQIGDIIRYRCLPGFTLLGSEILTCRLGERLQMDGPPPVCQVQCPDNEVLFDSTGVILSPGYPDSYPNLQMCSWMINVEKGYNITLHFQLFQTEKEFDILEIFDGPNIYSQSLAVLSGDLSVPFNITTTGHQLFLRWSSDHGTNKKGFRITYVGEYQTMYCSTPDSPQHGFVLSQTGGHVNSVVRWACDRGFRLIGKNMAVCKRTEIGFLAWDSSVPACQAVSCGMPVAPVNGGVLAADYSAGTRATYFCNDGFRLSSKEVTSTVCQADGTWSSHNKIPRCTVVVCPSIGSFTLDHGKWRIVNGSRYEYGTKVAFTCNAGYYRLGPAHIHCTSNGTWSWRNERPRCKVISCGELPTPPNGKKIGTQTTFGATAIFTCNSGFILVGSTVRECLPSGLWSGTETHCLAGHCGIPERIVNGQVIGENFGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVSISCGHPGSPIYGRTVGDGFNLNDVVTFFCNKGYILEGPSEAQCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYLFGSSVLTCQPVGYWDKPLPECLEVDCGHPGSPPHAVVTGDKFTFGSTVHYRCLEDRVLIGESTRACQLNGQWGGSQPHCSGDKRGACGDPGTPAHATREESSFQQHAKVRFTCSTGHTLYGSAERICFPNGTWSGRQPTCKPVQCGNPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPTRQCLANGTWSGGEPNCTLISCGDSGVPASGLRTGEDFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSCQAVTCSPPPAVSNGEVEGSVFEWGVSVSYRCMMGYELSFPAVLTCAGNGSWSGEIPLCLPKFCGDPGIPSRARREGQSFIFKAEVMFSCSAPYVLVGSSTRTCQADATWSGTQPRCIEPTRTTCENPGTPEFGSLNSSLGFKVGSTVKFVCQTGHLLLGSTTRTCQQDLTWSGSQPECIPHSCKQPKTPPHANVLGMDLPSFGYTLLYSCQPGFILTGGSEHRACRPDGSWTGKVPVCRAGSKTSEKVITPVQGTSSPKVNVPDDVFAPTFLWKGSFEYKGAKQPMTLTITSFNATTGKVNATLTNRHSELLLSGVYKSRDARLTLRLYHMKTLLKNTYSKTTEESMIMDGFVSADHEGNTYLFQGFIQGRDYGPFGLQRQGLNVLEPTRSPEIPPRTNSSSVAIAILVPFFALIFAGFGFYLYKQRKSDKAEYSGCSVHENNNGQATFENPMYNTNSKSIEGKVVRFDPNLNTVCTMV", "length": 3598, "header": "tr|A0A8M9PNC7-1|A0A8M9PNC7_DANRE Isoform 1 of CUB and sushi domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=csmd3a PE=3 SV=1 CANONICAL=A0A8M9PNC7-1" }, "locus": {} }, { "isoform_ac": "A0AB32T3A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNC7/entry#A0AB32T3A2-1", "sequence": { "sequence": "MKAADNEGWRGFLVLSHRGCIRCAHGTTMTIKTGFIIGNIVFCCILTCVQGFIYTCGGTLKGKNGTIESPGFPHGYPNGANCTWVIVAEERSRIHIVFQSFAVEEEYDFLSLYDGHPHPANFRTRLTGFQVPAPVTSTGSIFSLRLTSDFAVSAHGFKIYYEELQSSSCGNPGIPAKGILNGSSFNVGDRIRYHCVSGYTLDGHAQLTCVTSTSNVAVWDFPIPICRAEDTCGGTFRGASGTISSPDFQKDYQSSGECTWTILADPGDTISLVFTEFQMDSKLDSLEVEGSDPPTIWLSGINIPVPIVSNKNWLRLHFVTDNSHRHKGFSAQYQVKRSGDFKSRGVKLLPGKDNTSKFSIMNEGMVKQVSNFCPDPGEPENGKRIGTDYSIGATVQFTCDGDHVLQGSKSITCQRVAEVFAAWSDHRPVCKVKTCGMNLLGPSGTFTSPNFPIQYESNSQCVWIITASNPNKVIQINFEEFDLELGYDTLTVGDGGEVGDSKTIIQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGIPLYGLREGGGFSNGGVLRFECQFGFELIGERMISCQNNNQWSANIPICIFPCMSNFTAAMGTVLSPDYPEGYGNNLNCVWLIIAEAGSRIHLAFNDFDLEPPYDFLTVRDGDLADAVVLGRFSGAEVPSHLTSNSNILQLEFQADHSMSGRGFNITYSTFGHNECPDPGVPMNAKRFGNNFQLGSSISVVCEEGFIKTQGSDTIVCELEAGKVMWSGLIPKCEAPCGGHFTAPVGVILSPGWPGYYKDSLSCEWVIEAETGRSIKISFDRFQTELNYDFLEVHDGPNLLSPLIASLNGTQVPQFLFSSSNFLYLLFTTDNSRSNSGFKLFYESVTLDTHSCLDPGVPVNGVRYGQDLAIGSVVWFGCEPGYRLSHEEQLVCEKNHWWSHPLPTCDALCGGDVRGPEGIILSPGFPELYPNSLNCTWTLEVSHGKGVQFTFHAFHLEDHHDYLLLTENGSFVRPLARLTGSQRPPPVNAGLYGNFKAQLRFISDFSISFQGFNISFSEYDLEPCEDPGVPQFGRHSGGSFGIGDTLAFSCDPGYRLQGVPQISCLGGGRRIWSAPLPRCVAECGSTVSKNAGVLLSPNYPRNYDNNHECIYNIQVQAGKGINISASSFHLAQGDVLKLYDGPDNTADVLGAFSGSSMLSQSLTSTSNHLWLEFYSDQEDTAEGFKLAYTSFELSHCDEPGVPQFGSKVSDQGHFAGSVVTYHCDPGYSLHGSSILRCMTGERRTWDHPLPSCIAECGGSFKGESSGRILSPGYPFPYDNNLRCTWTIEVDSGNTVSLQFLAFDTEASHDILKVWDGHPENEMALKEVSGSLLPDGIHSTLNVVTIQFETDFYISKSGFAIDFSSSVATACRDPGTPMNGSRSGEGKEPGDTMTFACDPGYDLQGEPRITCIQVDNRFYWQPSPPTCIAPCGGNITGSSGFILSPNFPHPYPHSKDCDWFITVHPDYVISLAFISFSIEPNYDFLYIYDGPHSNSHLIGTFQDSKLPEKVESSSNIMHIAFRSDGSVSYTGFHLEYKAKLREACFDPGSVMNGTRLGGDYKLGSTVTFHCDPGYQLQGYSSLTCVMGATNRPEWNRALPSCQAPCGSRSTGSEGTILSPNYPRNYTTGQSCVYEISVPGEFVLFGQFMFFQTTSNDVVEIFDGASTESALLSSTYGSHSGEPLPLSSANEITIRFKTEGPNTAKGFHFVYQAVPRTSASQCSSVPEPRYGKRIGNDFGLGTVVLFECNPGYTLHGASAIRCEAVPNSLAQWNGTVPACVVACGGVLTTRRGTILSPGYPDPYDNHLNCVWKVFVPEGTGIQITVVTFSTEHNWDSLDFYDGIDSNAPRLGSYSGTTIPPLLNTTSNNLYLTFQTDMSVSGAGFHLEYTAIGLDSCPEPQTPGNGVKVGDRYFVGDVVSFHCEQGYTLKGSAYITCMPGPVRRWNYPAPLCLAQCGGFLTDLNGVILSPGFPGNYPSGLDCNWTVKLPIGFGIHLQFLNFSTESVHDYLEVRSGTLDSGSVIDRFSGPVVPESFFSTTHETSFFFHSDYSQNKPGFHITYEAYELQRCPDPRPFRNGVVIGSDFGVGMTISFQCLPGYTLLGESSLTCLHGVSRNWNHPVPRCEALCGGNITVLNGTIYSPGHPADYPNLKDCIWSIRVPPGNGIHINFTVLNTEPIYDYITIWDGPDQTSPQIGQFSGSLPQEPVSSTSNHILLKFHSDFSTSGFFVLRYHAYQLRVCQPPPPVANAEILAEDDEFQIGDIIRYRCLPGFTLLGSEILTCRLGERLQMDGPPPVCQVQCPDNEVLFDSTGVILSPGYPDSYPNLQMCSWMINVEKGYNITLHFQLFQTEKEFDILEIFDGPNIYSQSLAVLSGDLSVPFNITTTGHQLFLRWSSDHGTNKKGFRITYVAMYCSTPDSPQHGFVLSQTGGHVNSVVRWACDRGFRLIGKNMAVCKRTEIGFLAWDSSVPACQAVSCGMPVAPVNGGVLAADYSAGTRATYFCNDGFRLSSKEVTSTVCQADGTWSSHNKIPRCTVVVCPSIGSFTLDHGKWRIVNGSRYEYGTKVAFTCNAGYYRLGPAHIHCTSNGTWSWRNERPRCKVISCGELPTPPNGKKIGTQTTFGATAIFTCNSGFILVGSTVRECLPSGLWSGTETHCLAGHCGIPERIVNGQVIGENFGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVSISCGHPGSPIYGRTVGDGFNLNDVVTFFCNKGYILEGPSEAQCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYLFGSSVLTCQPVGYWDKPLPECLEVDCGHPGSPPHAVVTGDKFTFGSTVHYRCLEDRVLIGESTRACQLNGQWGGSQPHCSGDKRGACGDPGTPAHATREESSFQQHAKVRFTCSTGHTLYGSAERICFPNGTWSGRQPTCKPVQCGNPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPTRQCLANGTWSGGEPNCTLISCGDSGVPASGLRTGEDFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSCQAVTCSPPPAVSNGEVEGSVFEWGVSVSYRCMMGYELSFPAVLTCAGNGSWSGEIPLCLPKFCGDPGIPSRARREGQSFIFKAEVMFSCSAPYVLVGSSTRTCQADATWSGTQPRCIEPTRTTCENPGTPEFGSLNSSLGFKVGSTVKFVCQTGHLLLGSTTRTCQQDLTWSGSQPECIPHSCKQPKTPPHANVLGMDLPSFGYTLLYSCQPGFILTGGSEHRACRPDGSWTGKVPVCRAGSKTSEKVITPVQGTSSPKVNVPDDVFAPTFLWKGSFEYKGAKQPMTLTITSFNATTGKVNATLTNRHSELLLSGVYKSRDARLTLRLYHMKTLLKNTYSKTTEESMIMDGFVSADHEGNTYLFQGFIQGRDYGPFGLQRQGLNVLEPTRSPEIPPRTNSSSVAIAILVPFFALIFAGFGFYLYKQRKSDKAEYSGCSVHENNNGQATFENPMYNTNSKSIEGKVVRFDPNLNTVCTMV", "length": 3594, "header": "tr|A0AB32T3A2-1|A0A8M9PNC7_DANRE Computationally mapped isoform of CUB and sushi domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=csmd3a PE=3 SV=1 CANONICAL=A0A8M9PNC7-1" }, "locus": {} }, { "isoform_ac": "A0AB32TAA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNC7/entry#A0AB32TAA2-1", "sequence": { "sequence": "MKAADNEGWRGFLVLSHRGCIRCAHGTTMTIKTGFIIGNIVFCCILTCVQGFIYTCGGTLKGKNGTIESPGFPHGYPNGANCTWVIVAEERSRIHIVFQSFAVEEEYDFLSLYDGHPHPANFRTRLTGFQVPAPVTSTGSIFSLRLTSDFAVSAHGFKIYYEELQSSSCGNPGIPAKGILNGSSFNVGDRIRYHCVSGYTLDGHAQLTCVTSTSNVAVWDFPIPICRAEDTCGGTFRGASGTISSPDFQKDYQSSGECTWTILADPGDTISLVFTEFQMDSKLDSLEVEGSDPPTIWLSGINIPVPIVSNKNWLRLHFVTDNSHRHKGFSAQYQVKRSGDFKSRGVKLLPGKDNTSKFSIMNEGMVKQVSNFCPDPGEPENGKRIGTDYSIGATVQFTCDGDHVLQGSKSITCQRVAEVFAAWSDHRPVCKVKTCGMNLLGPSGTFTSPNFPIQYESNSQCVWIITASNPNKVIQINFEEFDLELGYDTLTVGDGGEVGDSKTIIQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGIPLYGLREGGGFSNGGVLRFECQFGFELIGERMISCQNNNQWSANIPICIFPCMSNFTAAMGTVLSPDYPEGYGNNLNCVWLIIAEAGSRIHLAFNDFDLEPPYDFLTVRDGDLADAVVLGRFSGAEVPSHLTSNSNILQLEFQADHSMSGRGFNITYSTFGHNECPDPGVPMNAKRFGNNFQLGSSISVVCEEGFIKTQGSDTIVCELEAGKVMWSGLIPKCEAPCGGHFTAPVGVILSPGWPGYYKDSLSCEWVIEAETGRSIKISFDRFQTELNYDFLEVHDGPNLLSPLIASLNGTQVPQFLFSSSNFLYLLFTTDNSRSNSGFKLFYESVTLDTHSCLDPGVPVNGVRYGQDLAIGSVVWFGCEPGYRLSHEEQLVCEKNHWWSHPLPTCDALCGGDVRGPEGIILSPGFPELYPNSLNCTWTLEVSHGKGVQFTFHAFHLEDHHDYLLLTENGSFVRPLARLTGSQRPPPVNAGLYGNFKAQLRFISDFSISFQGFNISFSEYDLEPCEDPGVPQFGRHSGGSFGIGDTLAFSCDPGYRLQGVPQISCLGGGRRIWSAPLPRCVAECGSTVSKNAGVLLSPNYPRNYDNNHECIYNIQVQAGKGINISASSFHLAQGDVLKLYDGPDNTADVLGAFSGSSMLSQSLTSTSNHLWLEFYSDQEDTAEGFKLAYTSFELSHCDEPGVPQFGSKVSDQGHFAGSVVTYHCDPGYSLHGSSILRCMTGERRTWDHPLPSCIAECGGSFKGESSGRILSPGYPFPYDNNLRCTWTIEVDSGNTVSLQFLAFDTEASHDILKVWDGHPENEMALKEVSGSLLPDGIHSTLNVVTIQFETDFYISKSGFAIDFSSSVATACRDPGTPMNGSRSGEGKEPGDTMTFACDPGYDLQGEPRITCIQVDNRFYWQPSPPTCIAPCGGNITGSSGFILSPNFPHPYPHSKDCDWFITVHPDYVISLAFISFSIEPNYDFLYIYDGPHSNSHLIGTFQDSKLPEKVESSSNIMHIAFRSDGSVSYTGFHLEYKAKLREACFDPGSVMNGTRLGGDYKLGSTVTFHCDPGYQLQGYSSLTCVMGATNRPEWNRALPSCQAPCGSRSTGSEGTILSPNYPRNYTTGQSCVYEISVPGEFVLFGQFMFFQTTSNDVVEIFDGASTESALLSSTYGSHSGEPLPLSSANEITIRFKTEGPNTAKGFHFVYQAVPRTSASQCSSVPEPRYGKRIGNDFGLGTVVLFECNPGYTLHGASAIRCEAVPNSLAQWNGTVPACVVACGGVLTTRRGTILSPGYPDPYDNHLNCVWKVFVPEGTGIQITVVTFSTEHNWDSLDFYDGIDSNAPRLGSYSGTTIPPLLNTTSNNLYLTFQTDMSVSGAGFHLEYTGLDSCPEPQTPGNGVKVGDRYFVGDVVSFHCEQGYTLKGSAYITCMPGPVRRWNYPAPLCLAQCGGFLTDLNGVILSPGFPGNYPSGLDCNWTVKLPIGFGIHLQFLNFSTESVHDYLEVRSGTLDSGSVIDRFSGPVVPESFFSTTHETSFFFHSDYSQNKPGFHITYEAYELQRCPDPRPFRNGVVIGSDFGVGMTISFQCLPGYTLLGESSLTCLHGVSRNWNHPVPRCEALCGGNITVLNGTIYSPGHPADYPNLKDCIWSIRVPPGNGIHINFTVLNTEPIYDYITIWDGPDQTSPQIGQFSGSLPQEPVSSTSNHILLKFHSDFSTSGFFVLRYHAYQLRVCQPPPPVANAEILAEDDEFQIGDIIRYRCLPGFTLLGSEILTCRLGERLQMDGPPPVCQVQCPDNEVLFDSTGVILSPGYPDSYPNLQMCSWMINVEKGYNITLHFQLFQTEKEFDILEIFDGPNIYSQSLAVLSGDLSVPFNITTTGHQLFLRWSSDHGTNKKGFRITYVGEYQTMYCSTPDSPQHGFVLSQTGGHVNSVVRWACDRGFRLIGKNMAVCKRTEIGFLAWDSSVPACQAVSCGMPVAPVNGGVLAADYSAGTRATYFCNDGFRLSSKEVTSTVCQADGTWSSHNKIPRCTVVVCPSIGSFTLDHGKWRIVNGSRYEYGTKVAFTCNAGYYRLGPAHIHCTSNGTWSWRNERPRCKVISCGELPTPPNGKKIGTQTTFGATAIFTCNSGFILVGSTVRECLPSGLWSGTETHCLAGHCGIPERIVNGQVIGENFGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVSISCGHPGSPIYGRTVGDGFNLNDVVTFFCNKGYILEGPSEAQCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYLFGSSVLTCQPVGYWDKPLPECLEVDCGHPGSPPHAVVTGDKFTFGSTVHYRCLEDRVLIGESTRACQLNGQWGGSQPHCSGDKRGACGDPGTPAHATREESSFQQHAKVRFTCSTGHTLYGSAERICFPNGTWSGRQPTCKPVQCGNPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPTRQCLANGTWSGGEPNCTLISCGDSGVPASGLRTGEDFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSCQAVTCSPPPAVSNGEVEGSVFEWGVSVSYRCMMGYELSFPAVLTCAGNGSWSGEIPLCLPKFCGDPGIPSRARREGQSFIFKAEVMFSCSAPYVLVGSSTRTCQADATWSGTQPRCIEPTRTTCENPGTPEFGSLNSSLGFKVGSTVKFVCQTGHLLLGSTTRTCQQDLTWSGSQPECIPHSCKQPKTPPHANVLGMDLPSFGYTLLYSCQPGFILTGGSEHRACRPDGSWTGKVPVCRAGSKTSEKVITPVQGTSSPKVNVPDDVFAPTFLWKGSFEYKGAKQPMTLTITSFNATTGKVNATLTNRHSELLLSGVYKSRDARLTLRLYHMKTLLKNTYSKTTEESMIMDGFVSADHEGNTYLFQGFIQGRDYGPFGLQRQGLNVLEPTRSPEIPPRTNSSSVAIAILVPFFALIFAGFGFYLYKQRKSDKAEYSGCSVHENNNGQATFENPMYNTNSKSIEGKVVRFDPNLNTVCTMV", "length": 3596, "header": "tr|A0AB32TAA2-1|A0A8M9PNC7_DANRE Computationally mapped isoform of CUB and sushi domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=csmd3a PE=3 SV=1 CANONICAL=A0A8M9PNC7-1" }, "locus": {} }, { "isoform_ac": "A0AC58HLH7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNC7/entry#A0AC58HLH7-1", "sequence": { "sequence": "MPDCTETSKPSSASSQTSPSPSRASTSRSQSMIWSHARTLACPSLAGTAVAALASATPWRSPVTLGTVCREFHRSAVWAAGGAYGVHLCQAECGSTVSKNAGVLLSPNYPRNYDNNHECIYNIQVQAGKGINISASSFHLAQGDVLKLYDGPDNTADVLGAFSGSSMLSQSLTSTSNHLWLEFYSDQEDTAEGFKLAYTSFELSHCDEPGVPQFGSKVSDQGHFAGSVVTYHCDPGYSLHGSSILRCMTGERRTWDHPLPSCIAECGGSFKGESSGRILSPGYPFPYDNNLRCTWTIEVDSGNTVSLQFLAFDTEASHDILKVWDGHPENEMALKEVSGSLLPDGIHSTLNVVTIQFETDFYISKSGFAIDFSSSVATACRDPGTPMNGSRSGEGKEPGDTMTFACDPGYDLQGEPRITCIQVDNRFYWQPSPPTCIAPCGGNITGSSGFILSPNFPHPYPHSKDCDWFITVHPDYVISLAFISFSIEPNYDFLYIYDGPHSNSHLIGTFQDSKLPEKVESSSNIMHIAFRSDGSVSYTGFHLEYKAKLREACFDPGSVMNGTRLGGDYKLGSTVTFHCDPGYQLQGYSSLTCVMGATNRPEWNRALPSCQAPCGSRSTGSEGTILSPNYPRNYTTGQSCVYEISVPGEFVLFGQFMFFQTTSNDVVEIFDGASTESALLSSTYGSHSGEPLPLSSANEITIRFKTEGPNTAKGFHFVYQAVPRTSASQCSSVPEPRYGKRIGNDFGLGTVVLFECNPGYTLHGASAIRCEAVPNSLAQWNGTVPACVVACGGVLTTRRGTILSPGYPDPYDNHLNCVWKVFVPEGTGIQITVVTFSTEHNWDSLDFYDGIDSNAPRLGSYSGTTIPPLLNTTSNNLYLTFQTDMSVSGAGFHLEYTAIGLDSCPEPQTPGNGVKVGDRYFVGDVVSFHCEQGYTLKGSAYITCMPGPVRRWNYPAPLCLAQCGGFLTDLNGVILSPGFPGNYPSGLDCNWTVKLPIGFGIHLQFLNFSTESVHDYLEVRSGTLDSGSVIDRFSGPVVPESFFSTTHETSFFFHSDYSQNKPGFHITYEAYELQRCPDPRPFRNGVVIGSDFGVGMTISFQCLPGYTLLGESSLTCLHGVSRNWNHPVPRCEALCGGNITVLNGTIYSPGHPADYPNLKDCIWSIRVPPGNGIHINFTVLNTEPIYDYITIWDGPDQTSPQIGQFSGSLPQEPVSSTSNHILLKFHSDFSTSGFFVLRYHAYQLRVCQPPPPVANAEILAEDDEFQIGDIIRYRCLPGFTLLGSEILTCRLGERLQMDGPPPVCQVQCPDNEVLFDSTGVILSPGYPDSYPNLQMCSWMINVEKGYNITLHFQLFQTEKEFDILEIFDGPNIYSQSLAVLSGDLSVPFNITTTGHQLFLRWSSDHGTNKKGFRITYVGEYQTMYCSTPDSPQHGFVLSQTGGHVNSVVRWACDRGFRLIGKNMAVCKRTEIGFLAWDSSVPACQAVSCGMPVAPVNGGVLAADYSAGTRATYFCNDGFRLSSKEVTSTVCQADGTWSSHNKIPRCTVVVCPSIGSFTLDHGKWRIVNGSRYEYGTKVAFTCNAGYYRLGPAHIHCTSNGTWSWRNERPRCKVISCGELPTPPNGKKIGTQTTFGATAIFTCNSGFILVGSTVRECLPSGLWSGTETHCLAGHCGIPERIVNGQVIGENFGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVSISCGHPGSPIYGRTVGDGFNLNDVVTFFCNKGYILEGPSEAQCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYLFGSSVLTCQPVGYWDKPLPECLEVDCGHPGSPPHAVVTGDKFTFGSTVHYRCLEDRVLIGESTRACQLNGQWGGSQPHCSGDKRGACGDPGTPAHATREESSFQQHAKVRFTCSTGHTLYGSAERICFPNGTWSGRQPTCKPVQCGNPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPTRQCLANGTWSGGEPNCTLISCGDSGVPASGLRTGEDFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSCQAVTCSPPPAVSNGEVEGSVFEWGVSVSYRCMMGYELSFPAVLTCAGNGSWSGEIPLCLPKFCGDPGIPSRARREGQSFIFKAEVMFSCSAPYVLVGSSTRTCQADATWSGTQPRCIEPTRTTCENPGTPEFGSLNSSLGFKVGSTVKFVCQTGHLLLGSTTRTCQQDLTWSGSQPECIPHSCKQPKTPPHANVLGMDLPSFGYTLLYSCQPGFILTGGSEHRACRPDGSWTGKVPVCRAGSKTSEKVITPVQGTSSPKVNVPDDVFAPTFLWKGSFEYKGAKQPMTLTITSFNATTGKVNATLTNRHSELLLSGVYKSRDARLTLRLYHMKTLLKNTYSKTTEESMIMDGFVSADHEGNTYLFQGFIQGRDYGPFGLQRQGLNVLEPTRSPEIPPRTNSSSVAIAILVPFFALIFAGFGFYLYKQRKSDKAEYSGCSVHENNNGQATFENPMYNTNSKSIEGKVVRFDPNLNTVCTMV", "length": 2563, "header": "tr|A0AC58HLH7-1|A0AC58HLH7_DANRE Computationally mapped isoform of CUB and sushi domain-containing protein 3 isoform X4 OS=Danio rerio OX=7955 GN=csmd3a PE=3 SV=1 CANONICAL=A0A8M9PNC7-1" }, "locus": {} }, { "isoform_ac": "A0AC58HLI3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNC7/entry#A0AC58HLI3-1", "sequence": { "sequence": "MPDCTETSKPSSASSQTSPSPSRASTSRSQSMIWSHARTLACPSLAGTAVAALASATPWRSPVTLGTVCREFHRSAVWAAGGAYGVHLCQAECGSTVSKNAGVLLSPNYPRNYDNNHECIYNIQVQAGKGINISASSFHLAQGDVLKLYDGPDNTADVLGAFSGSSMLSQSLTSTSNHLWLEFYSDQEDTAEGFKLAYTSFELSHCDEPGVPQFGSKVSDQGHFAGSVVTYHCDPGYSLHGSSILRCMTGERRTWDHPLPSCIAECGGSFKGESSGRILSPGYPFPYDNNLRCTWTIEVDSGNTVSLQFLAFDTEASHDILKVWDGHPENEMALKEVSGSLLPDGIHSTLNVVTIQFETDFYISKSGFAIDFSSSVATACRDPGTPMNGSRSGEGKEPGDTMTFACDPGYDLQGEPRITCIQVDNRFYWQPSPPTCIAPCGGNITGSSGFILSPNFPHPYPHSKDCDWFITVHPDYVISLAFISFSIEPNYDFLYIYDGPHSNSHLIGTFQDSKLPEKVESSSNIMHIAFRSDGSVSYTGFHLEYKAKLREACFDPGSVMNGTRLGGDYKLGSTVTFHCDPGYQLQGYSSLTCVMGATNRPEWNRALPSCQAPCGSRSTGSEGTILSPNYPRNYTTGQSCVYEISVPGEFVLFGQFMFFQTTSNDVVEIFDGASTESALLSSTYGSHSGEPLPLSSANEITIRFKTEGPNTAKGFHFVYQAVPRTSASQCSSVPEPRYGKRIGNDFGLGTVVLFECNPGYTLHGASAIRCEAVPNSLAQWNGTVPACVVACGGVLTTRRGTILSPGYPDPYDNHLNCVWKVFVPEGTGIQITVVTFSTEHNWDSLDFYDGIDSNAPRLGSYSGTTIPPLLNTTSNNLYLTFQTDMSVSGAGFHLEYTGLDSCPEPQTPGNGVKVGDRYFVGDVVSFHCEQGYTLKGSAYITCMPGPVRRWNYPAPLCLAQCGGFLTDLNGVILSPGFPGNYPSGLDCNWTVKLPIGFGIHLQFLNFSTESVHDYLEVRSGTLDSGSVIDRFSGPVVPESFFSTTHETSFFFHSDYSQNKPGFHITYEAYELQRCPDPRPFRNGVVIGSDFGVGMTISFQCLPGYTLLGESSLTCLHGVSRNWNHPVPRCEALCGGNITVLNGTIYSPGHPADYPNLKDCIWSIRVPPGNGIHINFTVLNTEPIYDYITIWDGPDQTSPQIGQFSGSLPQEPVSSTSNHILLKFHSDFSTSGFFVLRYHAYQLRVCQPPPPVANAEILAEDDEFQIGDIIRYRCLPGFTLLGSEILTCRLGERLQMDGPPPVCQVQCPDNEVLFDSTGVILSPGYPDSYPNLQMCSWMINVEKGYNITLHFQLFQTEKEFDILEIFDGPNIYSQSLAVLSGDLSVPFNITTTGHQLFLRWSSDHGTNKKGFRITYVGEYQTMYCSTPDSPQHGFVLSQTGGHVNSVVRWACDRGFRLIGKNMAVCKRTEIGFLAWDSSVPACQAVSCGMPVAPVNGGVLAADYSAGTRATYFCNDGFRLSSKEVTSTVCQADGTWSSHNKIPRCTVVVCPSIGSFTLDHGKWRIVNGSRYEYGTKVAFTCNAGYYRLGPAHIHCTSNGTWSWRNERPRCKVISCGELPTPPNGKKIGTQTTFGATAIFTCNSGFILVGSTVRECLPSGLWSGTETHCLAGHCGIPERIVNGQVIGENFGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVSISCGHPGSPIYGRTVGDGFNLNDVVTFFCNKGYILEGPSEAQCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYLFGSSVLTCQPVGYWDKPLPECLEVDCGHPGSPPHAVVTGDKFTFGSTVHYRCLEDRVLIGESTRACQLNGQWGGSQPHCSGDKRGACGDPGTPAHATREESSFQQHAKVRFTCSTGHTLYGSAERICFPNGTWSGRQPTCKPVQCGNPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPTRQCLANGTWSGGEPNCTLISCGDSGVPASGLRTGEDFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSCQAVTCSPPPAVSNGEVEGSVFEWGVSVSYRCMMGYELSFPAVLTCAGNGSWSGEIPLCLPKFCGDPGIPSRARREGQSFIFKAEVMFSCSAPYVLVGSSTRTCQADATWSGTQPRCIEPTRTTCENPGTPEFGSLNSSLGFKVGSTVKFVCQTGHLLLGSTTRTCQQDLTWSGSQPECIPHSCKQPKTPPHANVLGMDLPSFGYTLLYSCQPGFILTGGSEHRACRPDGSWTGKVPVCRAGSKTSEKVITPVQGTSSPKVNVPDDVFAPTFLWKGSFEYKGAKQPMTLTITSFNATTGKVNATLTNRHSELLLSGVYKSRDARLTLRLYHMKTLLKNTYSKTTEESMIMDGFVSADHEGNTYLFQGFIQGRDYGPFGLQRQGLNVLEPTRSPEIPPRTNSSSVAIAILVPFFALIFAGFGFYLYKQRKSDKAEYSGCSVHENNNGQATFENPMYNTNSKSIEGKVVRFDPNLNTVCTMV", "length": 2561, "header": "tr|A0AC58HLI3-1|A0AC58HLI3_DANRE Computationally mapped isoform of CUB and sushi domain-containing protein 3 isoform X5 OS=Danio rerio OX=7955 GN=csmd3a PE=3 SV=1 CANONICAL=A0A8M9PNC7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2655, "start_aa": "Thr", "end_pos": 2655, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2655", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2952, "start_aa": "Thr", "end_pos": 2952, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2952", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3010, "start_aa": "Thr", "end_pos": 3010, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3010", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:565916", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565916", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5XWT0-1", "protein_name": "CD55 molecule (Cromer blood group)", "gene_name": "Cd55", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIRTRAPGTRAPPPPPLLLSLSLLLLLLSPTVSGDCGPPPDIPNATPNSGKHTKFAHQSQVTYSCNKGFKQIPDKPNTVVCLENDQWSNYETFCNKTCSAPLRLNYASLKKEYRNMNFFPIGTTVEFECRPGFQKVTSRTGKSTCLEELVWSPVVEFCKKRACPNPRELKNGHINIPTDILFGSEIIFSCDKGYKLVGVTSTFCSITGNAVDWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTYSCDQGFILVGNSSVHCTLNGEVGEWSSAPPKCIERHKVPTKTPPEVDIPSTMPHESTLINFPSTRAPLSHKPTTVKVPGTRVKPTSHKPTEVKVPGTRVPPTSQKHTTVNVPSTRVPATSQKPSMVHVSDTRVSPKPQKPTKANNPSTEIPPTPQKANTADVPSTESPPTPQKANTAVVPATEIPPAPQKTNTAVAPATEIPPTPQKTNTADVPSTESPPTPQKANTADVPATEIPPALQKANTAVVPATETLPTPQKANTAIVPATETPPAPQKTNTAVAPSTEIPPTPQKANTADVPATEIPPTPQNANTADVPSTEIPPTPQKSNTADVPATEIPPTPQKANTADVPATEIPPTPQNANTADVPSTEIPPTPQKTNTAKVSAIKPATAQMSLISTTVFAQTPPITQHPTTVNSSAVQTAQTTRGFATAKPSLTQNPPATQRPTISHFSMTKGLHTVTQIFTSAHITATQHVPVSKTTVRHPTRTSKDRGESNSGGDHFIYGHTCLITMTILHVMLLLTG", "length": 773 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A4X5-1", "protein_name": "CUB and sushi domain-containing protein 3", "gene_name": "Csmd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKGSRKGESRAKESKPREPGTRRCAKCGRLDFILKKKMGIKSGFTFWNLVFLLTLSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPGFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSPLTLTASIGELEKHIRTATVANTPADVTVSSVTAVTSHRLSEEQRVQVRSLSDSGLDPNTSEDQLSPHQADTQSTSRRPRNAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSLLNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMRSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPDSPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGPIPRCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDPGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSELPSTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRVGFSFGVGDTLTFSCSLGYRLEGSSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSLQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDSEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENEMLLKEVSGSLIPDGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGQERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTVSVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRVLPSCHAPCGSRSTGSEGTVLSPNYPKNYSVDHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVFDGPTQQSPLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNDFAVGSLVLFECNPGYILHGSRAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQIVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKVGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIRLPIGFGVHLQFVNFSTETIHDYLEVRSGSSELSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNISMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSAAFNVTSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHSWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTATCQSDGTWSNHNKTPRCVVVTCPSINSFTLEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRTERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSGSETRCLAGHCGIPDLIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGIPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDPGMPGHGSRQESDFRTKSTVRFACDTGYILYGSEERTCLSNGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGNLPNCTIISCGDPGIPANGLRYGDDFVVGQNVSYMCQPGYTMELNGSRVRTCTTNGTWSGVMPTCRAVTCSTPPQISNGRLEGTNFDWGFSISYICSAGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPSQGKREGKSFIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLADLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSDMELLLSGVYKSQEARLMLHIYLIKVPANASVKKMKEENWAMDGFVSAEPDGATYVFQGFIKGKDYGQFGLQRLGLNTSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "length": 3703 }, "evidence": [ { "id": "RGD:1594530", "url": "https://alliancegenome.org/gene/RGD:1594530#orthology", "database": "AGR" }, { "id": "HGNC:19291", "url": "https://alliancegenome.org/gene/HGNC:19291#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-118#orthology", "database": "AGR" }, { "id": "MGI:2386403", "url": "https://alliancegenome.org/gene/MGI:2386403#orthology", "database": "AGR" }, { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1NL34-1", "protein_name": "E-selectin precursor", "gene_name": "sele", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDICNKLQFFASFVLISSALNLWRCSEGWSYHYSDSTMTWQNARNWCRQHYTDLVAIQNKNEIAHLNGILPRRNGYYWIGIRKINNQWTWVGTNKTLTAEAENWAEKEPNNKGNNQDCVEIYIQREKDEGKWNDESCSKSKTALCYTASCASDSCVSGHGECVETINSHTCSCFEGFYGKVCENVVKCEPNEVNALDHSSKQCSHPHGNFAYDSQCEYSCEEGYELKGSSTTRCNFTAEWTSKPPSCELVQCPQLNKPLKGGMQCNHPMGQFSYQSSCEFVCDEGYKLRDSSSSTLICGATGHWNDSQPTCEIVKCKAKDITPPAHAKVHCTNEDIPYKSQCEYSCEEGYELKGSSTTTCTSTTEWSSEPTTCELVQCPALEKPVNGDLSCTLSFSYGSKCSFSCGEGFILTGVSETSCTKTAEWSQEPPRCEVVQCSELANPQKGGMQCNHPMGQFSYQSSCEFVCDEGYKLQNSSSSTLICGATGLWNDSQPTCEIVKCKARDLTTPANAKVHCTNENIPYESQCEYSCEEGYELKGSSTTMCTSTTEWSNEPPTCELVQCPELAKPLEGDMYCNHPMGQFSYLSSCTFVCDEGYNLRDSSSSTLICGATGHWNDSQPTCEIVKCKEEDITPPAHAKVHCTNEDIPYESQCEYSCEEGYELKGSSTTTCTSTTEWSSEPTICELIQCPALDNLVNGDLSCNSSFSYGSKCSFSCAEGFILQGASEISCTNTAEWSQKPPHCEAVVCPQLSDPANGYTNCSSDEPFFGTICNFICFDGHQLDSNETVMCSHDGRWSGEVAVCQAQPGPSKSLFKATEVALGVAGTVGSSSLFLVYWILKKLKSNANKFKLNSTLDTVDPPQAYKSSIDSLL", "length": 872 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2B906-1", "protein_name": "Regulator of complement activation group 2 gene 1 isoform X1", "gene_name": "rca2.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPRNVLSLAVALFSCLLMCTHVQGECTLPSFESRNVVLSGSYSPGQTLPDGSALTFECLSGHTPVDSRATKSITCTKSQWTDLGLSCKKKSCGSPPEIVNGRYEISGILFGDTIKPICNTGYMLVGYGLDQRVCRDGGWDGRDPECEVVKCAAPPSIENGQLSDEPLESYEYSQVVTYRCNSGFSLSGSSNLHCSDDGTFKPDPPKCLDGCPKPEIPHAIRIGGRSPPYKIGHFIEYKCEDLYTLKGIKEIACRAGGWDPEPPKCIEPCRVPNFGGNVTLREEFSSKDLFPHGDKVAFKCKSGYEPVDSTVSRIATCEETKWTKLLLTCKASPTTTTTARAPTTARTPTSHTTSKVLPDGDEEKSSSSSAPLGAILGGIFGSGGLLLLGCFGVYMLVTKQSKRKQKVPTNEEGSL", "length": 415 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B6F5-1", "protein_name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 isoform X1", "gene_name": "si:ch73-217n20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATVWRNALVLVFVHLVVSQTRFRCGEPPKYPDKQLDIKYIYRPVFNHQDKVSYRCHRGHVPSEGNRMSFCMRGRWTPLTLKCQKVKCNGLADIKNGQYRREGQSYGDKAIVICNQGYVLKGVKFRMCLEKGWSGTDPVCLAPQVTCSAPTVENRWIKPGERTQYTTQDTVSITCSEGFDLIGSSVVTCGPNGQWRDLPECHRKVPKMTCPAPAVENRSIKPGERTQYTPQDTVSITCSEGFDLIGSSLVTCGPDGQWQNLPKCHRKVILCSAPAVANGRINAFGNQHKPRDTVSITCSEGFELIGSPQVTCGPDGQWQSLPECHPKRRSANVIFCSAPVVANGRINAFGNQHKPKDTVSITCSEGFELIGSSQVTCGPDGQWQGLPECHPKKHLVNVNLCSAPAVANGRINEFGNTFKPKDTVSIICSEGFDLIGSPQVTCGPDGQWQSLPECHPKTRLANGKCGPPPSYLHHNVFFREGTPSLTEYSSGARIRYKCNLGLRRASGSDIIRCQAGEWTKLALRCQRKSCGSAGEISFGRFQYSGVLFGDSARAICQEGYELIGPEERVCRDGGWDGRIPVCEPVYCPPPPEVKDAEVSDFRNEDVPVGHMVSYRCQTGALIGTQDLYCTTNGTWSGPAPLCKDISCPRPDIPRGSRMRGFRSVYKYGNTVTIACSPGLRLYGESFVTCGADGNWTPKLPECRR", "length": 704 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PNP5-1", "protein_name": "CUB and sushi domain-containing protein 3 isoform X1", "gene_name": "csmd3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHIDDTEGHSVRSTGFLAVFKRGCIRCGPVDSQAKKMGIKTGVTFWNLIFFMMVTCVRGFIYTCGGTLKGRNGTIESPGFPYGYQNGANCTWVIVAEEGNRIQIVFQSFAVEEDYDFLSLYDGHPHPANFRTRLTGFQIPPPVTSTGSVFSLRLTSDFAVSAHGFKIYYEELQSSSCGNPGVPPKGILYGTRFNVGDKIRYSCVTGYVLDGHPQLTCVTNAGNAAVWDFPVPICRAEDTCGDTLRGSSGIITSPNFPSEYYNSADCTWTILADPGDTISIIFTDFQTEEKYDYLEVEGSEPPTIWLSGMNVPSPIVSNKNWLRLHFVTDSNHRYKGFSAHYQVKRSVDFKSRGVKLFPGKDNSNKFSILNEGGIKQASNSCPDPGEPENGKRIGNDFSIGATAEFTCDEDHVLQGSKSITCQRVAEVFAAWTDHRPVCRVKTCGSNLQGPSGTFSSPNFPIQYESNSQCVWIITASNLNKVIQINFEDFDLELGYDTLTIGDGGEVGDPKTILQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGTPLYGMREGDGFSNGDMLRFECQFGFELIGEKTISCQNNNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCVWLILSEPGSRIHLAFNDFDLEAPYDILTVKDGEMLDSSVLGRFTGAEVPSHLTSNSNILRLEFQADHSMSGRGFNITYTTFGHNECPDPGIPLNARRFGDSFQLGSSISIICEDGFIKTQGAETITCELNGGKVMWSGPIPKCEAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGRSIKITFEKFQTELNCDFLELHDGPNLLSPLIGSFNGTQVPQFLFSSGNHLYMLFTTDNSRSNSGFKILYESVTVDAYSCLDPGIPVNGLRYGQDFSIGSTVSFGCDSGYRLSHEEPLVCEKNHWWSHPLPTCDALCGGDVRGPGGTILSPGYPEVYPSSLNCTWTVEVSHGKGVQFTFNTFHLEDHHDYLLITENGSFVQPLARLTGAELPLPINAGLYGNFKAQLRFISDFSISYEGFNITFSEYNLEPCEDPGVPHYGRRNGYSFGIGDTLTFSCNLGYRLEGAPEIICLGGGRRMWSAPLPRCVAECGSSVINNEGILLSPNYPMNYENNHECIYSIQVQAGKGINISARTFHLAQGDILKIYDGKDNAAHMLGAFTGSSMLGLTLISTSNHLWLEFYSDAEATGEGFKLVYSSFELSHCEDPGVPQFGFKVNDQGHFSGSTITYKCDPGYTLHGSGVLKCMTGERRAWDNALPSCIAECGGRFKGETSGRILSPGYPFPYDNNLRCTWMVEVDSGNIISLQFLAFDTEASHDILRVWDGPPENEMSLREVSGSLLPENVHSTLNMVSIQFETDFYISKSGFAIEFSSSVATACRDPGVPMNGSRNGDGREPGDTVTFQCDPGYELQGDVKITCIQVENRYYWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSKDCDWLIAVNSDYVLSLAFISFSIEPNYDFLYIYDGADSNSPLIGSFQDSKLPERIESSSNTMYLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNVMNGTRLGSDYKLGSTVTFYCEAGYVLQGYSTLTCIMGDDGRPGWNRGLPSCQAPCGSRSTGTDGTVLSPNFPRNYTTGQSCVYTIAVPREFVLFGQFVLFQTSLNDVVDIYDGPTQQSSLLSSLSGSHSGESLPLSTGNQITIKFSTVGPETAKGFHFVYQAVPRTSATQCSSVPEPRFGKRIGNNFAVGASVMFECNPGYTLHGSTAIHCETVPDALAQWNDTLPTCIVPCGGILTMRKGTILSPGYPEPYDNNLNCVWKVSVPEGAGIQIQVVSFATEHNWDSLDFYDGADNNAPRLGSYSGTTIPQLLNSTSNNLYLNFVSDISVSAAGFHLEYTAIGLDTCPEPQTPTYGIKIGDRYMVGDVVMFQCEQGYSLQGNAHITCMPGPVRRWNYPVPLCLAQCGGAMTEVSGVILSPGFPGNYPSGLDCTWTITLPIGFGIHVQFLNFSTEAIHDYLEIRSGPSETGTVIDRFSGPQVPESLFSTTHETSFFFHSDYSQNKPGFHITYQAYQLQSCPDPRPFRNGIVIGSDFSVGMTVSFECLPGYSLIGETSLTCLHGISRNWNNPIPRCEALCGGNITSMNGTIFSPGHPAEYPNFQDCVWSVRVPPGNGIYINFTVLSTEPIYDYITVWDGPDQSSPQIGQFSGNTALESVYSTSNQILIKFHSDFSGSGFFVLSYHAYQLRVCQPPLEVANADILMEDNELEIGDIIRYRCHPGFTLVGSEILTCRLGERLQMDGHPPSCQVQCPAHDVRFDSSGVILSPGYPDSYPNLQMCSWSINVEKGYNITLFFEFFQTEKEYDILEVFDGPTIHSQTLATLSGDLPTPFNMTTSGHQLLLRWSADHGTNKKGFSIRYVGEYQTLYCSTPDSPLHGSISSQTGGHLNSLVRWTCDRGYRLIGKSTAVCKKTPFGFYDWDAPVPACQAVSCGVPKAPVNGGVLAMDYSVGTRVTYFCSDGYRLSSKELTSAVCQPDGTWSNHNKVPRCSVVVCPSIGSFSLEHGRWRIVNGSHYEYRTKIIFTCDPGYYRLGPAYIQCMANGAWSWKNERPHCQIISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCLAGHCGLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIGSSVRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNMGYVMEGPSRAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMDGYLLSGSTTRQCQANGTWSGTAPNCTLINCGEPGVPANGLRYGEDFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVTCTAPPPISNGLLEGRDFEWGTSVSYSCSPGYELSFPAILTCVGNGTWSGEVPQCLPKFCGDPGTPAFGSREGRSFIYQSEVSFSCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPRYGSLNRTFGFKVGSMVAFQCQPGHLLQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHVDVVGMDLPSYGYTLIYSCQSGFFLSGGSEHRVCRSDGTWTGKMPVCRAGSKLSEKPIKPVPGTPSPKLNVPDDVFAPNYIWKGSYNYKGRKQPMTLSITSFNTTTGRVNVTLTSSNMELLLSGVYKSQEARLMLLVYHVKASSSSTLSKIKEEHWTLDGFVSAEPDGSTYVFQGFIQGKDYGQFGLQRLGLNMSESNNSSNPPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTTPKTQYTGCSVHENNNGQAAFENPMYNTKPEVKNVRFDPNLNTVCTMV", "length": 3603 }, "evidence": [ { "id": "RGD:1594530", "url": "https://alliancegenome.org/gene/RGD:1594530#orthology", "database": "AGR" }, { "id": "HGNC:19291", "url": "https://alliancegenome.org/gene/HGNC:19291#orthology", "database": "AGR" }, { "id": "MGI:2386403", "url": "https://alliancegenome.org/gene/MGI:2386403#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A3V1-1", "protein_name": "Beta-2-glycoprotein 1", "gene_name": "ntd5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MERSLLVAFVCVWALSSLSAASEDAAEQCPERILGNERRQTCPKKCQQDKDCGNKRQCLCDGQCGLSCVVPGRMCPWPLPLGKHSDIVLLSPSPSFSALLEVRCKSGYTLSNGLDTTIRRCQGDRQWSGDEPVCSAPPGGDVSAGPGLVPDVSCSLPEDDDLLSVQGSATTGSTIKYRCASGSVLIGNSENICHENQTWQYPHPICRRVVCPPPKEVADRGHLVAVQRTEYDVGDTIYYLCKKTFLLDGPNQVTCLPNGTWSAEPACRARCPVPAQRSRVIVGGVKRWPYDLTDGVVAHGENVTFFCKHPEKLCSFTATEVCVDGELKAPSCYLDPTWLQFKLYPHRLVSEIDACDRADLQ", "length": 361 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32T6Z7-1", "protein_name": "E-selectin", "gene_name": "selp", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQCNCLNSKSHLTVILYALLCKFPFRFHANKTELCQKKMVLLVHITLFSGSLVFMTGMYNVNAWTYHYNIDSKLDWTAARQWCQTHFTDMVAIQNQAEIAYLNEILPFHRAYYWIGIRKIDGHWTWVGTKKRLTVEAANWATNEPNNQGTGEDCVEIYIKRNKDTAKWNDERCSKKKATVCYLASCTEISCSEHARCVETIGNYTCQCDAGFMGPRCEEVVQCQPVENPQQGLVKCDGAFGEFNFNSSCQFQCATGFNLVGAERIHCLTTGHWNDTLPVCQAVKCQAIIDAPRGWTMICTHPLSMNSFNSSCEFECKEGFELNGSKTTWCDHTGHWTDKAPTCTVVTCNPLLAPANSSLACADPLGKSSFRSSCNVTCDEGYKLRGRAALTCQREGNWSAPLPVCEVVKCDSLKPIANGSYQCHDSVDEFSYGSTCWFKCDSGFVHNGTNSTHCTKQGNWSHISPICHAVQCPPLSDTPKYGSVSCVHPLSTNSYNSSCEFKCEEGLVLRGTDSTHCDHTGHWTNTAPICTAVACDPLVTPVNSNLTCANPLGKFSFRTSCEVICEVGYKLRGDTTLNCLSNGNWSAPTPACKVIRCEALESVHHGSVHCHDLLEEFSYGSECWLECEAGFTLNGTNSTYCTSQGKWKQELSVCQAQQCSSLTDPSHGSLTCTHPHGQFSFGTVCEVSCQAGFKLHGTPKMECLEMGKWTDTPPFCLAQECPLLSAPENGWMNCSHPHSLFSYESQCLLGCETGFELTGEPDIQCSASGNWSQEMPSCAVVHCEPLWLTHLSDLGPPPSMNCSHPHGNFSFGSQCMFWCANSHELNGTSQLVCTSNGYWTHSPPICVVKEMSVSASMLIYAAVGAVSSAGLLLLGGLIFLLTRQITKKAHYSLNKSSLEGDLNLAFELN", "length": 909 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2AVA0-1", "protein_name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", "gene_name": "Svep1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWSRLAFCCWALALVSGWTNFQPVAPSLNFSFRLFPEASPGALGRLAVPPASSEEEAAGSKVERLGRAFRSRVRRLRELSGSLELVFLVDESSSVGQTNFLNELKFVRKLLSDFPVVSTATRVAIVTFSSKNNVVARVDYISTSRAHQHKCALLSREIPAITYRGGGTYTKGAFQQAAQILRHSRENSTKVIFLITDGYSNGGDPRPIAASLRDFGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQEDMARCSYLCEAGKDCCDRMASCKCGTHTGQFECICEKGYYGKGLQHECTACPSGTYKPEASPGGISTCIPCPDVSHTSPPGSTSPEDCVCREGYQRSGQTCEVVHCPALKPPENGFFIQNTCKNHFNAACGVRCRPGFDLVGSSIHLCQPNGLWSGTESFCRVRTCPHLRQPKHGHISCSTAEMSYNTLCLVTCNEGYRLEGSTRLTCQGNAQWDGPEPRCVERHCATFQKPKGVIISPPSCGKQPARPGMTCQLSCRQGYILSGVREVRCATSGKWSAKVQTAVCKDVEAPQISCPNDIEAKTGEQQDSANVTWQVPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAITYTATDSSGNQASCTFYIKVIDVEPPVIDWCRSPPPIQVVEKEHPASWDEPQFSDNSGAELVITSSHTQGDMFPHGETVVWYTATDPSGNNRTCDIHIVIKGSPCEVPFTPVNGDFICAQDSAGVNCSLSCKEGYDFTEGSTEKYYCAFEDGIWRPPYSTEWPDCAIKRFANHGFKSFEMLYKTTRCDDMDLFKKFSAAFETTLGNMVPSFCNDADDIDCRLEDLTKKYCIEYNYNYENGFAIGPGGWGAGNRLDYSYDHFLDVVQETPTDVGKARSSRIKRTVPLSDPKIQLIFNITASVPLPEERNDTLELENQQRLIKTLETITNRLKSTLNKEPMYSFQLASETVVADSNSLETEKAFLFCRPGSVLRGRMCVNCPLGTSYSLEHSTCESCLMGSYQDEEGQLECKLCPPRTHTEYLHSRSVSECKAQCKQGTYSSSGLETCESCPLGTYQPEFGSRSCLLCPETTTTVKRGAVDISACGVPCPVGEFSRSGLTPCYPCPRDYYQPNAGKSFCLACPFYGTTTITGATSITDCSSFSSTFSAAEESIVPLVAPGHSQNKYEVSSQVFHECFLNPCHNSGTCQQLGRGYVCLCPPGYTGLKCETDIDECSSLPCLNGGICRDQVGGFTCECSLGYSGQICEENINECISSPCLNKGTCTDGLASYRCTCVKGYMGVHCETDVNECQSSPCLNNAVCKDQVGGFSCKCPPGFLGTRCEKNVDECLSQPCQNGATCKDGANSFRCQCPAGFTGTHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGHRCETEQPSGFNLDFEVSGIYGYVLLDGVLPTLHAITCAFWMKSSDVINYGTPISYALEDDKDNTFLLTDYNGWVLYVNGKEKITNCPSVNDGIWHHIAITWTSTGGAWRVYIDGELSDGGTGLSIGKAIPGGGALVLGQEQDKKGEGFNPAESFVGSISQLNLWDYVLSPQQVKLLASSCPEELSRGNVLAWPDFLSGITGKVKVDSSSMFCSDCPSLEGSVPHLRPASGNRKPGSKVSLFCDPGFQMVGNPVQYCLNQGQWTQPLPHCERIRCGLPPALENGFYSAEDFHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSYVCSCNPPYTGDGKNCAEPVKCKAPENPENGHSSGEIYTVGTAVTFSCDEGHELVGVSTITCLETGEWDRLRPSCEAISCGVPPVPENGGVDGSAFTYGSKVVYRCDKGYTLSGDEESACLASGSWSHSSPVCELVKCSQPEDINNGKYILSGLTYLSIASYSCENGYSLQGPSLLECTASGSWDRAPPSCQLVSCGEPPIVKDAVITGSNFTFGNTVAYTCKEGYTLAGPDTIVCQANGKWNSSNHQCLAVSCDEPPNVDHASPETAHRLFGDTAFYYCADGYSLADNSQLICNAQGNWVPPAGQAVPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECLRGGEWSPSPLSVQCIPVRCGEPPSIANGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEATGQWSKPTPTCHPVSCNEPPKVENGFLEHTTGRTFESEARFQCNPGYKAAGSPVFVCQANRHWHSDAPLSCTPLNCGKPPPIQNGFLKGESFEVGSKVQFVCNEGYELVGDNSWTCQKSGKWSKKPSPKCVPTKCAEPPLLENQLVLKELASEVGVMTISCKEGHALQGPSVLKCLPSGQWNGSFPICKMVLCPSPPLIPFGVPASSGALHFGSTVKYLCVDGFFLRGSPTILCQADSTWSSPLPECVPVECPQPEEILNGIIHVQGLAYLSTTLYTCKPGFELVGNATTLCGENGQWLGGKPMCKPIECPEPKEILNGQFSSVSFQYGQTITYFCDRGFRLEGPKSLTCLETGDWDMDPPSCDAIHCSDPQPIENGFVEGADYRYGAMIIYSCFPGFQVLGHAMQTCEESGWSSSSPTCVPIDCGLPPHIDFGDCTKVRDGQGHFDQEDDMMEVPYLAHPQHLEATAKALENTKESPASHASHFLYGTMVSYSCEPGYELLGIPVLICQEDGTWNGTAPSCISIECDLPVAPENGFLHFTQTTMGSAAQYSCKPGHILEGSHLRLCLQNKQWSGTVPRCEAISCSKPNPLWNGSIKGDDYSYLGVLYYECDSGYILNGSKKRTCQENRDWDGHEPMCIPVDCGSPPVPTNGRVKGEEYTFQKEITYSCREGFILEGARSRICLTNGSWSGATPSCMPVRCPAPPQVPNGVADGLDYGFKKEVAFHCLEGYVLQGAPRLTCQSNGTWDAEVPVCKPATCGPPADLPQGFPNGFSFYHGGHIQYQCFTGYKLHGNPSRRCLPNGSWSGSSPSCLPCRCSTPIIQQGTINATDLGCGKTVQIECFKGFKLLGLSEITCDANGQWSDVPLCEHAQCGPLPTIPNAIVLEGSLSEDNVVTYSCRPGYTMQGSSDLICTEKAIWSQPYPTCEPLSCGPPPTVANAVATGEAHTYESKVKLRCLEGYVMDSDTDTFTCQQDGHWVPERITCSPKKCPVPSNMTRIRFHGDDFQVNRQVSVSCAEGFTHEGVNWSTCQPDGTWEPPFSDESCIPVVCGHPESPAHGSVVGNKHSFGSTIVYQCDPGYKLEGNRERICQENRQWSGEVAVCRENRCETPAEFPNGKAVLENTTSGPSLLFSCHRGYTLEGSPEAHCTANGTWNHLTPLCKPNPCPVPFVIPENAVLSEKEFYVDQNVSIKCREGFLLKGNGVITCSPDETWTHTNARCEKISCGPPSHVENAIARGVYYQYGDMITYSCYSGYMLEGSLRSVCLENGTWTPSPVCRAVCRFPCQNGGVCQRPNACSCPDGWMGRLCEEPICILPCLNGGRCVAPYQCDCPTGWTGSRCHTATCQSPCLNGGKCIRPNRCHCLSAWTGHDCSRKRRAGL", "length": 3567 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z9F7-1", "protein_name": "Complement component receptor 1-like protein", "gene_name": "Cr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGALGSLWVFFALIAPGVLGQCKLLPKYSFAKPTVVSDKSEFAVGTTWKYKCLPGYFRKSFTITCLESSKWSDAQQFCKRKPCMNPQEPLHGSVHINTGITFGSTITYSCNKGYRLIGDSSATCIISDNTVMWDNSVPICELIPCESPPAISNGYFQSSSRDSFFYGMVATYYCHVGKNREKLFDLVGEKSIYCTSKDNQVGIWNSPPPQCIARVKCPMPEIENGDVESGFKPSFFLNDTVMFKCKSGFIMKGSSIVWCQPDSKWSPPLPTCFRGCLPPQNILHGDYNEKDKEFFSVGQKVSYSCEPGYTLIGTNLVECTPLGAWSPSVPTCEVKSCDAIPNQLLNGRVLLPHNLQLGAEVSFVCDLGFQLKGKSSSQCVPEGETVIWNNKFPVCEQLSCDPPPEVNNTRRLYYSLPVLPGTVVRYTCLPGYRLIGEKAIFCISKDQVTATWDKATPICEPWNKMSACSKPIVPGGIINPGSRPPFKHGDSVTVTCKANFTMKGSKTVWCRANKMWGPTPLPVCESDFPLECPSLPTIHNGHHTGQHVEKFVAGLSVTYSCEPGYLLVGKKTIKCLSSGAWDDVIPTCKEAKCERPEKLPNGQVKEPPSLRVGTTVYFSCNEGYELQGQPSSKCVIVEQKAVWTKKPVCKEILCPPPPPVLNGRHSGRFSGNVPYGNNVTYMCDPSPEKGVNFTLIGEKTIYCTNSSEKTGIWSGPAPYCKLSISEAQCLRPQINRGQILSILKESYSYNDTVAFSCEPGFTLKGSGRIRCSAQGTWKPPVPVCEKGCQAPPKIINGQKEDRYFLNFDPGTSIRYSCDPGYFLVGEDTIHCTSEGKWTPIPPQCKVAECKPVGPHVFERPQNHFIRPAINSSCDEGFQISESAYQLCQGTIPWFIEIRLCKEITCPPPPIILNGTHTWRSSEDVPYGTVITYMCYPGSEEGVKFKLIGEQTIHCTSDSRGRGSWSSPAPLCKLSLPAVQCTEVHVENGVKLTDNKAPYFYNNSVTFKCRDGYILIGSSQIRCKANNTWDPEAPHCKKEGCEPMRKLPGISDHSLIKLVNRTCQNGYQLTGYTYEKCQNAENGTWFQKIAVCTVILCPPPPTIANGSHTGMMAEHFLYGNEVSYECDKGFYLLGEKSLQCKGHGSWSGPPPQCLQSSPLTHCPDPEVKYGYKLNKTHSAYSHNDIIHVVCNQGFIMNGSHLIRCHTNNTWLPGVPTCIRTASLGCQSPPTIPNGNHTGGTIARFSPGMSVMYSCYQGYLMAGEARLICTHEGTWSHPAPYCKEVNCSFPEDTNGIQKGFQPGKTYRFGTTVTLECEDGYSLEGSPQSQCQDENQWNPPLAICKNRSTVPLVSGISAGSAFIILISVIFFIILKSRERNYYTKTRPKDGALHLETREVYAVDPYNPAS", "length": 1406 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P02749-1", "protein_name": "Beta-2-glycoprotein 1", "gene_name": "APOH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISPVLILFSSFLCHVAIAGRTCPKPDDLPFSTVVPLKTFYEPGEEITYSCKPGYVSRGGMRKFICPLTGLWPINTLKCTPRVCPFAGILENGAVRYTTFEYPNTISFSCNTGFYLNGADSAKCTEEGKWSPELPVCAPIICPPPSIPTFATLRVYKPSAGNNSLYRDTAVFECLPQHAMFGNDTITCTTHGNWTKLPECREVKCPFPSRPDNGFVNYPAKPTLYYKDKATFGCHDGYSLDGPEEIECTKLGNWSAMPSCKASCKVPVKKATVVYQGERVKIQEKFKNGMLHGDKVSFFCKNKEKKCSYTEDAQCIDGTIEVPKCFKEHSSLAFWKTDASDVKPC", "length": 345 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P04003-1", "protein_name": "C4b-binding protein alpha chain", "gene_name": "C4BPA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHPPKTPSGALHRKRKMAAWPFSRLWKVSDPILFQMTLIAALLPAVLGNCGPPPTLSFAAPMDITLTETRFKTGTTLKYTCLPGYVRSHSTQTLTCNSDGEWVYNTFCIYKRCRHPGELRNGQVEIKTDLSFGSQIEFSCSEGFFLIGSTTSRCEVQDRGVGWSHPLPQCEIVKCKPPPDIRNGRHSGEENFYAYGFSVTYSCDPRFSLLGHASISCTVENETIGVWRPSPPTCEKITCRKPDVSHGEMVSGFGPIYNYKDTIVFKCQKGFVLRGSSVIHCDADSKWNPSPPACEPNSCINLPDIPHASWETYPRPTKEDVYVVGTVLRYRCHPGYKPTTDEPTTVICQKNLRWTPYQGCEALCCPEPKLNNGEITQHRKSRPANHCVYFYGDEISFSCHETSRFSAICQGDGTWSPRTPSCGDICNFPPKIAHGHYKQSSSYSFFKEEIIYECDKGYILVGQAKLSCSYSHWSAPAPQCKALCRKPELVNGRLSVDKDQYVEPENVTIQCDSGYGVVGPQSITCSGNRTWYPEVPKCEWETPEGCEQVLTGKRLMQCLPNPEDVKMALEVYKLSLEIEQLELQRDSARQSTLDKEL", "length": 597 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08174-1", "protein_name": "Complement decay-accelerating factor", "gene_name": "CD55", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTVARPSVPAALPLLGELPRLLLLVLLCLPAVWGDCGLPPDVPNAQPALEGRTSFPEDTVITYKCEESFVKIPGEKDSVICLKGSQWSDIEEFCNRSCEVPTRLNSASLKQPYITQNYFPVGTVVEYECRPGYRREPSLSPKLTCLQNLKWSTAVEFCKKKSCPNPGEIRNGQIDVPGGILFGATISFSCNTGYKLFGSTSSFCLISGSSVQWSDPLPECREIYCPAPPQIDNGIIQGERDHYGYRQSVTYACNKGFTMIGEHSIYCTVNNDEGEWSGPPPECRGKSLTSKVPPTVQKPTTVNVPTTEVSPTSQKTTTKTTTPNAQATRSTPVSRTTKHFHETTPNKGSGTTSGTTRLLSGHTCFTLTGLLGTLVTMGLLT", "length": 381 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08607-1", "protein_name": "C4b-binding protein", "gene_name": "C4bpa", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCAKQQQTLLPTRAAHGRLHRNRDAVAWPFSTLCRVSGPTLFQMTFTAALWVAVFGKCGPPPAIPNALPASDVNRTDFESHTTLKYECLPGYGRGISRMMVYCKPSGEWEISVSCAKKHCRNPGYLDNGYVNGETITFGSQIEFSCQEGFILVGSSTSSCEVRGKGVAWSNPFPECVIVKCGPPPDISNGKHSGTEDFYPYNHGISYTCDPGFRLVGSPFIGCTVVNKTVPVWSSSPPTCEKIICSQPNILHGVIVSGYKATYTHRDSVRLACLNGTVLRGRHVIECQGNGNWSSLPTCEFDCDLPPAIVNGYYTSMVYSKITLVTYECDKGYRLVGKAIISCSFSKWKGTAPQCKALCQKPEVGNGTLSDEKDQYVESENVTIQCDSGFAMLGSQSISCSESGTWYPEVPRCEQEASEDLKPALTGNKTMQYVPNSHDVKMALEIYKLTLEVELLQLQIQKEKHTEAH", "length": 469 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P0C6B8-1", "protein_name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", "gene_name": "Svep1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWTRLAFCCWALALVSGWTNFQPMAPSLNFSFRLFPEASPGALGRLAVPPRSGEEEAVGSKVERLGRTFRSRVRRLRELSDRLELVFLVDESSSVGQTNFLNELKFVRKLLSDFPVVSTATRVAIVTFSSKNNVVARVDYISTSRAHQHKCALLSREIPAITYRGGGTYTMGAFQQAAQILRHSRENSTKVIFLITDGYSNGGDPRPIAASLRDFGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQEDMAHCSYLCEAGRDCCDRMASCKCGTHTGQFECICEKGYYGKGLQYECTACPPGTYKPEASPGGISTCIPCPDENHTSPPGSTAPEDCVCREGYQRSGQTCEVVHCPALKPPENGFFIQNTCKNHFNAACGVRCRPGFDLVGSSIHLCQPNGLWSGTESFCRVRTCPHLRQPKHGHISCSTVEMSYNTVCLVTCNEGYRLEGHAKLTCQGNAQWDGTEPRCVERHCATFQKPKGVIISPPSCGKQPAKPGMICQLGCRQGYILSGIREVRCATSGKWSARVQTAVCKDVEAPQISCPNDIKAKTEGQQDSANVTWQVPTAKDNSGEKVSVHVHPAFSPPYLFPIGEVAITYTATDSSGNQASCTFYIKVIDVEPPVIDWCRSPPPIQVVEKEHPASWDEPQFSDNSGAELVITSSHTQGDLFPHGETVVWYTATDPSGNNRTCDIHIVIKGSPCEVPFTPVNGDFICAQDSAGVNCSLTCREGYDFTEGSTEKYYCAFEDGIWRPPYSTEWPDCAIKRFANHGFKSFEMLYKTTRCDDMDLFKKFSAAFETTLGKMVPSFCSDADDIDCRLEDLTKKYCIEYNYNYENGFAIGPGGWGAGNRLDYSYDHFLDVVQETPADVGKTRSSRIKRTVPLSDPQIQLIFNITASVPLPEERNDTVELENQQRLIRTLETITNRLKSTLNKGPMYSFQLASETVVADSNSLETEKAFLFCRPGSVLRGRMCVNCPLGTSYSLEHSTCESCLMGSYQDEEGQLECKLCPPRTHTEYLHSRSISECKAQCKQGTYSSSGLETCESCPLGTYQPDFGSRSCLPCPETTTTVKRGAVDISACGVPCPVGEFSRSGLTPCYPCPRDYYQPNAGKSFCLACPFYGTTTITGATSITDCSSFSSTFSAAEESIVPLAAPGPTQNKYEVFHECFLNPCHNSGTCQQLGRGYVCLCPPGYTGLKCETDIDECSSLPCLNGGICRDKVGGFTCECSSGYTGQICEENINECSSSPCLNKGTCTDGLASYRCTCVSGYVGVHCETDVNECQSSPCLNNAVCKDQVGGFSCKCPPGFLGTRCEKNVDECLSQPCQNGATCKDGANSFRCQCPAGFTGPHCELNINECQSNPCRNQATCVDELNSYSCKCRPGFSGRRCETEQPSGFNLDFEVSGIYGYVLLDGVLPTLHAITCAFWMKSSDVINYGTPISYALEGNKDNTFLLTDYNGWVLYVNGKEKITNCPSVNDGIWHHIAITWTSTGGAWRVYIDGELSDSGTGLSVGKAIPGGGALVLGQEQDKKGEGFNPAESFVGSISQLNLWDYVLSPQQVKSLASSCPEELSRGNVLAWPDFVSGITGKVKVDSSSIFCSDCPSLEGSVPHLRPASGDRKPGSKVSLFCDPGFQMVGNPVQYCLNQGQWSQPLPHCERIRCGLPPTLENGFYSAEDLHAGSTVTYQCTSGYYLLGDSRMFCTDNGSWNGISPSCLDVDECAVGSDCSEHASCLNTNGSYICSCKPPYTGDGKNCAEPVKCKAPENPENGHSLGKIYSVGAEVTFSCEEGHQLVGVRKITCLESGEWDHLRPSCEAISCGAPPVPENGGVDGSAFTYGSKVRYRCDKGYTLAGDEESACLASGSWSHSSPVCELVKCSQPENINNGKYILSGLTYLSIASYSCEDGYSLQGPSLIECTASGSWDRAPPSCQLVSCGEPPMVKDALTTGSNFTFGNMVTYTCKEGYTLAGPDTIICQANGKWNSSNHQCLAVSCDEPPNVDHASPETAHRLFGDTAFYYCADGYSLADNSQLICNAQGNWVPPEGQAVPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECLRGGQWSPSPLSVQCIPVRCGEPPSITNGYPSGTNYSFGAVVAYSCHKGFYIKGEKKSTCEATGQWSRPLPTCHPVSCNEPPKVENGFLEHTTGRTFESEARFQCNPGYKAVGSPVFVCQANRHWHSDAPLSCTPLNCGKPPPIQNGFLRGESFEVGSKVQFVCNEGYELVGDNSWTCQKSGKWSKKPSPKCVPTKCAEPPLLENQLVLKELTSEVGVMTISCKEGHALQGPSVLKCLPSGQWNGSFPVCKLVLCQSPPLIPFGVPASSGALHFGSTVKYLCVDGFFLRGNPIILCQVDGTWSSPLPECVPVECPQPEEILNGIIHVQGLAYLSTTLYTCKPGFELVGNTTTLCGENGQWLGGKPMCRPIECPEPKEILNGQFSSVSFQYGQTITYSCDRGFRLEGPKSLTCLETGNWDMDAPSCNAIHCSDPQPIENGFVEGADYRYGAMIIYSCFPGFQVVGHAMQTCEETGWSSSSPTCVPIDCGLPPHIDFGDCTRVSDGQGYFVQEDDMMEVPYLTPHPQHLEATAKASEITEESLVPHASQFLYGTTVSYRCEPGYELLGIPVLVCQEDGTWNGTAPSCISIECDLPVAPENGFLHFTQTTMGSAAQYSCKPGHVLEGSHLRLCLQNKQWSGTVPRCEVISCSEPNPLGNGSIKGNDYSYLGVLHYECDSGYVLNGTEKRTCQENKQWDGHEPVCLPVDCGSPPVPTNGQVTGEEYTFQKEIAYSCGEGFILEGARSRVCLTNGSWSGTTPSCVPVRCPAPPQVANGVTDGLDYGFKKEVTFHCLEGYVLQGTPKLTCQSNGTWDAEVPICKPATCGPPADLPQGFPNGFSFFHGGHIQYQCFTGYKLHGNPSRRCLPDGSWSGSTPSCLPCTCSTPIIQQGTVNATDLGCGKTVQIECFKGFKLLGLPEITCDANGQWSDFPLCEHADCGPLPTVPNGIVIKGSPSEDNVVTYSCRPGYIIQGSSDLICTEKGIWSEPYPTCEPVSCGPPPTVANAVATGEAHTYESKVKLRCLEGYVVDTDTDTFTCQQDGRWFPERINCSPKTCPVPSNRTRIRVHGDDFQVNRQVSVSCTEGFTYDGADRSTCQPDGTWEPPLSEESCIPVVCGQPESPEHGFVVGSEYSFGSTVVYQCDPGYELEGNRERVCQENRQWSGRVAVCRESRCEAPAEFPNGKAVLENTTSGPSLLFSCHRGYTLEGPPEAHCTANGTWSHLAPLCKPNPCPVPFVIPENALLSEREFYVNQNVSIKCREGFLLKGNGIITCNPDETWTQTNARCEKISCGPPTHVENAIARGVHYQYGDMVTFSCYSGYMLEGSLRSVCLENGTWTPPPICRAVCRFPCQNGGVCQRPNACSCPDGWMGRLCEEPICILPCLNGGRCVAPYRCDCPAGWTGSRCHTATCQSPCLNGGKCVRPNRCHCLSSWTGHDCSRKRRSGL", "length": 3564 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P16109-1", "protein_name": "P-selectin", "gene_name": "SELP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKAYSWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKALTNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSKQGECLETIGNYTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHCTDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSFSCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSCKFECQPGYRVRGLDMLRCIDSGHWSAPLPTCEAISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGFMLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNEGLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIKCPELFAPEQGSLDCSDTRGEFNVGSTCHFSCDNGFKLEGPNNVECTTSGRWSATPPTCKGIASLPTPGVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPACRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTVPTCQAGPLTIQEALTYFGGAVASTIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSHLGTYGVFTNAAFDPSP", "length": 830 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16581-1", "protein_name": "E-selectin", "gene_name": "SELE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQNKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDCVEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSGLKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWSAPIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGNWDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTTQGQWTQQIPVCEAFQCTALSNPERGYMNCLPSASGSFRYGSSCEFSCEQGFVLKGSKRLQCGPTGEWDNEKPTCEAVRCDAVHQPPKGLVRCAHSPIGEFTYKSSCAFSCEEGFELHGSTQLECTSQGQWTEEVPSCQVVKCSSLAVPGKINMSCSGEPVFGTVCKFACPEGWTLNGSAARTCGATGHWSGLLPTCEAPTESNIPLVAGLSAAGLSLLTLAPFLLWLRKCLRKAKKFVPASSCQSLESDGSYQKPSYIL", "length": 610 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P19070-1", "protein_name": "Complement receptor type 2", "gene_name": "Cr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLTWFLFYFSEISCDPPPEVKNARKPYYSLPIVPGTVLRYTCSPSYRLIGEKAIFCISENQVHATWDKAPPICESVNKTISCSDPIVPGGFMNKGSKAPFRHGDSVTFTCKANFTMKGSKTVWCQANEMWGPTALPVCESDFPLECPSLPTIHNGHHTGQHVDQFVAGLSVTYSCEPGYLLTGKKTIKCLSSGDWDGVIPTCKEAQCEHPGKFPNGQVKEPLSLQVGTTVYFSCNEGYQLQGQPSSQCVIVEQKAIWTKKPVCKEILCPPPPPVRNGSHTGSFSENVPYGSTVTYTCDPSPEKGVSFTLIGEKTINCTTGSQKTGIWSGPAPYCVLSTSAVLCLQPKIKRGQILSILKDSYSYNDTVAFSCEPGFTLKGNRSIRCNAHGTWEPPVPVCEKGCQAPPKIINGQKEDSYLLNFDPGTSIRYSCDPGYLLVGEDTIHCTPEGKWTPITPQCTVAECKPVGPHLFKRPQNQFIRTAVNSSCDEGFQLSESAYQLCQGTIPWFIEIRLCKEITCPPPPVIHNGTHTWSSSEDVPYGTVVTYMCYPGPEEGVKFKLIGEQTIHCTSDSRGRGSWSSPAPLCKLSLPAVQCTDVHVENGVKLTDNKAPYFYNDSVMFKCDDGYILSGSSQIRCKANNTWDPEKPLCKKEGCEPMRVHGLPDDSHIKLVKRTCQNGYQLTGYTYEKCQNAENGTWFKKIEVCTVILCQPPPKIANGGHTGMMAKHFLYGNEVSYECDEGFYLLGEKSLQCVNDSKGHGSWSGPPPQCLQSSPLTHCPDPEVKHGYKLNKTHSAFSHNDIVHFVCNQGFIMNGSHLIRCHTNNTWLPGVPTCIRKASLGCQSPSTIPNGNHTGGSIARFPPGMSVMYSCYQGFLMAGEARLICTHEGTWSQPPPFCKEVNCSFPEDTNGIQKGFQPGKTYRFGATVTLECEDGYTLEGSPQSQCQDDSQWNPPLALCKYRRWSTIPLICGISVGSALIILMSVGFCMILKHRESNYYTKTRPKEGALHLETREVYSIDPYNPAS", "length": 1025 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P26644-1", "protein_name": "Beta-2-glycoprotein 1", "gene_name": "Apoh", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MISPALIFFSAFLCHVAIAGRRMWPINTLKCTPRVCPFAGILENGVVRYTTFEYPNTIGFACNPGYYLNGTSSSKCTEEGKWSPELPVCARITCPPPPIPKFAALKEYKTSVGNSSFYQDTVVFKCLPHFAMFGNDTVTCTAHGNWTQLPECREVKCPFPSRPDNGFVNYPAKPVLSYKDKAVFGCHETYKLDGPEEVECTKTGNWSALPSCKASCKLSVKKATVLYQGQRVKIQDQFKNGMMHGDKVHFYCKNKEKKCSYTEEAQCIDGTIEIPKCFKEHSSLAFWKTDASDVTPC", "length": 297 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P98105-1", "protein_name": "E-selectin", "gene_name": "Sele", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNASCFLSALTFVLLIGKSIAWYYNASSELMTYDEASAYCQRDYTHLVAIQNKEEINYLNSTLRYSPSYYWIGIRKVNNVWIWVGTQKPLTEEAKNWAPGEPNNKQRNEDCVEIYIQRPKDSGMWNDERCDKKKLALCYTASCTNTSCSGHGECVETINSYTCKCHPGFLGPKCDQVVTCQEQEYPDHGSLNCTHPFGLFSYNSSCSFSCERGYVPSSMETTVRCTSSGEWSAPAPACHVVECKALTQPAHGVRKCSSNPGSYPWNTTCTFDCEEGYRRVGAQNLQCTSSGVWDNEKPSCKAVTCDAIPRPQNGSVSCSNSTAGALAFKSSCNFTCEHSFTLQGPAQVECSAQGQWTPQIPVCKASQCEALSAPQRGHMKCLPSASAPFQSGSSCKFSCDEGFELKGSRRLQCGPRGEWDSEKPTCAGVQCSSLDLPGKMNMSCSGPAVFGTVCEFTCPEGWTLNGSSILTCGATGRWSAMLPTCEAPANPPRPLVVALSVAATSLLTLSSLIYVLKRFFWKKAKKFVPASSCQSLQSFENYQGPSYII", "length": 549 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P98106-1", "protein_name": "P-selectin", "gene_name": "Selp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGCPKGSWKPRLRSVVLGAAQLIWLSALISELVNRKKVATWTYNYSTKAYSWNNSRAFCKRHFTDLVAIQNKNEIAHLNDVIPYVNSYYWIGIRKINNKWTWVGTNKTLTAEAENWADNEPNNKRNNQDCVEIYIKSNSAPGKWNDEPCFKRKRALCYTASCQDMSCNSQGERIETIGSYTCSCYPGFYGPECEYVQECGKFDIPQHVLMNCSHPLGDFSFSSQCTFSCPEGYDLNGPSEMQCLASGIWTNNPPQCKAVQCQSLEAPLHGTMDCTHPLAAFAYDSSCKFECQPGYRMRGSDILHCTDSGQWSEPLPTCEAIACEPLESPLHGSMDCFPSTGAFGYNSSCTFRCTEGFVLMGNDAIHCADLGQWTAPAPVCEALQCQEFPVPSKAQVSCSDPFGPLKYQSACSFSCDEGSLLVGASVIRCLATGHWSEAPPECQAVSCTPLLSPENGTMTCIQPLGHSNYKSTCQFMCDEGFYLSGPERLDCSPSGHWTGSPPMCEAIKCPEIFAPEQGSLDCSHVHGEFSVGSTCHFSCNEEFELLGSRNVECTVSGRWSAPPPTCKGVTSLPVPSVRCPALTTPGQGTMSCRHHLESFGPNTTCYFGCKTGFTLRGANSLRCGASGQWTAVTPVCRAVKCSELHMDTAVAMNCSNPWGNFSYGSTCAFHCPEGQSLNGSARTTCGEDGHWSDAMPTCQAGTLTIQEALTYLGGALASTSGLAVGGTLLALLRKRLRKKDDGKCPLNPHSHLGTYGVFTNAAYDPTP", "length": 768 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q01339-1", "protein_name": "Beta-2-glycoprotein 1", "gene_name": "Apoh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSPVLALFSAFLCHVAIAGRICPKPDDLPFATVVPLKTSYDPGEQIVYSCKPGYVSRGGMRRFTCPLTGMWPINTLRCVPRVCPFAGILENGIVRYTSFEYPKNISFACNPGFFLNGTSSSKCTEEGKWSPDIPACARITCPPPPVPKFALLKDYRPSAGNNSLYQDTVVFKCLPHFAMIGNDTVMCTEQGNWTRLPECLEVKCPFPPRPENGYVNYPAKPVLLYKDKATFGCHETYKLDGPEEAECTKTGTWSFLPTCRESCKLPVKKATVLYQGMRVKIQEQFKNGMMHGDKIHFYCKNKEKKCSYTVEAHCRDGTIEIPSCFKEHSSLAFWKTDASELTPC", "length": 345 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4LDE5-1", "protein_name": "Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1", "gene_name": "SVEP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWPRLAFCCWGLALVSGWATFQQMSPSRNFSFRLFPETAPGAPGSIPAPPAPGDEAAGSRVERLGQAFRRRVRLLRELSERLELVFLVDDSSSVGEVNFRSELMFVRKLLSDFPVVPTATRVAIVTFSSKNYVVPRVDYISTRRARQHKCALLLQEIPAISYRGGGTYTKGAFQQAAQILLHARENSTKVVFLITDGYSNGGDPRPIAASLRDSGVEIFTFGIWQGNIRELNDMASTPKEEHCYLLHSFEEFEALARRALHEDLPSGSFIQDDMVHCSYLCDEGKDCCDRMGSCKCGTHTGHFECICEKGYYGKGLQYECTACPSGTYKPEGSPGGISSCIPCPDENHTSPPGSTSPEDCVCREGYRASGQTCELVHCPALKPPENGYFIQNTCNNHFNAACGVRCHPGFDLVGSSIILCLPNGLWSGSESYCRVRTCPHLRQPKHGHISCSTREMLYKTTCLVACDEGYRLEGSDKLTCQGNSQWDGPEPRCVERHCSTFQMPKDVIISPHNCGKQPAKFGTICYVSCRQGFILSGVKEMLRCTTSGKWNVGVQAAVCKDVEAPQINCPKDIEAKTLEQQDSANVTWQIPTAKDNSGEKVSVHVHPAFTPPYLFPIGDVAIVYTATDLSGNQASCIFHIKVIDAEPPVIDWCRSPPPVQVSEKVHAASWDEPQFSDNSGAELVITRSHTQGDLFPQGETIVQYTATDPSGNNRTCDIHIVIKGSPCEIPFTPVNGDFICTPDNTGVNCTLTCLEGYDFTEGSTDKYYCAYEDGVWKPTYTTEWPDCAKKRFANHGFKSFEMFYKAARCDDTDLMKKFSEAFETTLGKMVPSFCSDAEDIDCRLEENLTKKYCLEYNYDYENGFAIGPGGWGAANRLDYSYDDFLDTVQETATSIGNAKSSRIKRSAPLSDYKIKLIFNITASVPLPDERNDTLEWENQQRLLQTLETITNKLKRTLNKDPMYSFQLASEILIADSNSLETKKASPFCRPGSVLRGRMCVNCPLGTYYNLEHFTCESCRIGSYQDEEGQLECKLCPSGMYTEYIHSRNISDCKAQCKQGTYSYSGLETCESCPLGTYQPKFGSRSCLSCPENTSTVKRGAVNISACGVPCPEGKFSRSGLMPCHPCPRDYYQPNAGKAFCLACPFYGTTPFAGSRSITECSSFSSTFSAAEESVVPPASLGHIKKRHEISSQVFHECFFNPCHNSGTCQQLGRGYVCLCPLGYTGLKCETDIDECSPLPCLNNGVCKDLVGEFICECPSGYTGQRCEENINECSSSPCLNKGICVDGVAGYRCTCVKGFVGLHCETEVNECQSNPCLNNAVCEDQVGGFLCKCPPGFLGTRCGKNVDECLSQPCKNGATCKDGANSFRCLCAAGFTGSHCELNINECQSNPCRNQATCVDELNSYSCKCQPGFSGKRCETEQSTGFNLDFEVSGIYGYVMLDGMLPSLHALTCTFWMKSSDDMNYGTPISYAVDNGSDNTLLLTDYNGWVLYVNGREKITNCPSVNDGRWHHIAITWTSANGIWKVYIDGKLSDGGAGLSVGLPIPGGGALVLGQEQDKKGEGFSPAESFVGSISQLNLWDYVLSPQQVKSLATSCPEELSKGNVLAWPDFLSGIVGKVKIDSKSIFCSDCPRLGGSVPHLRTASEDLKPGSKVNLFCDPGFQLVGNPVQYCLNQGQWTQPLPHCERISCGVPPPLENGFHSADDFYAGSTVTYQCNNGYYLLGDSRMFCTDNGSWNGVSPSCLDVDECAVGSDCSEHASCLNVDGSYICSCVPPYTGDGKNCAEPIKCKAPGNPENGHSSGEIYTVGAEVTFSCQEGYQLMGVTKITCLESGEWNHLIPYCKAVSCGKPAIPENGCIEELAFTFGSKVTYRCNKGYTLAGDKESSCLANSSWSHSPPVCEPVKCSSPENINNGKYILSGLTYLSTASYSCDTGYSLQGPSIIECTASGIWDRAPPACHLVFCGEPPAIKDAVITGNNFTFRNTVTYTCKEGYTLAGLDTIECLADGKWSRSDQQCLAVSCDEPPIVDHASPETAHRLFGDIAFYYCSDGYSLADNSQLLCNAQGKWVPPEGQDMPRCIAHFCEKPPSVSYSILESVSKAKFAAGSVVSFKCMEGFVLNTSAKIECMRGGQWNPSPMSIQCIPVRCGEPPSIMNGYASGSNYSFGAMVAYSCNKGFYIKGEKKSTCEATGQWSSPIPTCHPVSCGEPPKVENGFLEHTTGRIFESEVRYQCNPGYKSVGSPVFVCQANRHWHSESPLMCVPLDCGKPPPIQNGFMKGENFEVGSKVQFFCNEGYELVGDSSWTCQKSGKWNKKSNPKCMPAKCPEPPLLENQLVLKELTTEVGVVTFSCKEGHVLQGPSVLKCLPSQQWNDSFPVCKIVLCTPPPLISFGVPIPSSALHFGSTVKYSCVGGFFLRGNSTTLCQPDGTWSSPLPECVPVECPQPEEIPNGIIDVQGLAYLSTALYTCKPGFELVGNTTTLCGENGHWLGGKPTCKAIECLKPKEILNGKFSYTDLHYGQTVTYSCNRGFRLEGPSALTCLETGDWDVDAPSCNAIHCDSPQPIENGFVEGADYSYGAIIIYSCFPGFQVAGHAMQTCEESGWSSSIPTCMPIDCGLPPHIDFGDCTKLKDDQGYFEQEDDMMEVPYVTPHPPYHLGAVAKTWENTKESPATHSSNFLYGTMVSYTCNPGYELLGNPVLICQEDGTWNGSAPSCISIECDLPTAPENGFLRFTETSMGSAVQYSCKPGHILAGSDLRLCLENRKWSGASPRCEAISCKKPNPVMNGSIKGSNYTYLSTLYYECDPGYVLNGTERRTCQDDKNWDEDEPICIPVDCSSPPVSANGQVRGDEYTFQKEIEYTCNEGFLLEGARSRVCLANGSWSGATPDCVPVRCATPPQLANGVTEGLDYGFMKEVTFHCHEGYILHGAPKLTCQSDGNWDAEIPLCKPVNCGPPEDLAHGFPNGFSFIHGGHIQYQCFPGYKLHGNSSRRCLSNGSWSGSSPSCLPCRCSTPVIEYGTVNGTDFDCGKAARIQCFKGFKLLGLSEITCEADGQWSSGFPHCEHTSCGSLPMIPNAFISETSSWKENVITYSCRSGYVIQGSSDLICTEKGVWSQPYPVCEPLSCGSPPSVANAVATGEAHTYESEVKLRCLEGYTMDTDTDTFTCQKDGRWFPERISCSPKKCPLPENITHILVHGDDFSVNRQVSVSCAEGYTFEGVNISVCQLDGTWEPPFSDESCSPVSCGKPESPEHGFVVGSKYTFESTIIYQCEPGYELEGNRERVCQENRQWSGGVAICKETRCETPLEFLNGKADIENRTTGPNVVYSCNRGYSLEGPSEAHCTENGTWSHPVPLCKPNPCPVPFVIPENALLSEKEFYVDQNVSIKCREGFLLQGHGIITCNPDETWTQTSAKCEKISCGPPAHVENAIARGVHYQYGDMITYSCYSGYMLEGFLRSVCLENGTWTSPPICRAVCRFPCQNGGICQRPNACSCPEGWMGRLCEEPICILPCLNGGRCVAPYQCDCPPGWTGSRCHTAVCQSPCLNGGKCVRPNRCHCLSSWTGHNCSRKRRTGF", "length": 3571 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60736-1", "protein_name": "Zona pellucida sperm-binding protein 3 receptor", "gene_name": "Zp3r", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MITWSFIDLWRTSHSTLFQMTLATVLMAPVLGDCGPPPLLPFASPTNQLYESTTFPSGTVLKYTCHHGFKRVNSSHLSCDENGSWVYSTFCARKRCKNPGELVNGKVEIPSDLLVGSIIEFSCSKGYLLIGSATSRCEVQGKGVDWSDSLPECVIATCEPPPPISNGKHSGRDDDLYTFGSVVIYNCDPTFTLLGNASIVCTVVNRTVGVWRPHPPACQKIVCHRPQIPKGYLAPGFRQFYAYRDALEIRCKKGFILRGSSVIHCEANGEWFPSIPTCEPNGCTNIPDISYASWEGYKFPLRNFEVFEIGAKLKYQCKPGYRASLNDPQTVTCQENLTWSSTNGCERICCPTPDMEKIKIVSERRDFTGTCIYAYGDYVFYICNEGSYPMSTDGRSSCQADGKWDPAIPSCQADSGLQNRLALFTFPNISETNVTNKTYLFGHEENSTEHAMKGVCLKPMVINGNLSVERVIYAELENITIQCDPGYTIVGSPNIICSNRTWYPEVPSCQMEVLEDCRIVSRGAQLLHCLSSPEDVHRALKVYKLFLEIERLEHQKEKWIQLHRKPQSMKINRSFRLCN", "length": 579 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q61475-1", "protein_name": "Complement decay-accelerating factor, GPI-anchored", "gene_name": "Cd55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIRGRAPRTRPSPPPPLLPLLSLSLLLLSPTVRGDCGPPPDIPNARPILGRHSKFAEQSKVAYSCNNGFKQVPDKSNIVVCLENGQWSSHETFCEKSCVAPERLSFASLKKEYLNMNFFPVGTIVEYECRPGFRKQPPLPGKATCLEDLVWSPVAQFCKKKSCPNPKDLDNGHINIPTGILFGSEINFSCNPGYRLVGVSSTFCSVTGNTVDWDDEFPVCTEIHCPEPPKINNGIMRGESDSYTYSQVVTYSCDKGFILVGNASIYCTVSKSDVGQWSSPPPRCIEKSKVPTKKPTINVPSTGTPSTPQKPTTESVPNPGDQPTPQKPSTVKVSATQHVPVTKTTVRHPIRTSTDKGEPNTGGDRYIYGHTCLITLTVLHVMLSLIGYLT", "length": 390 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q61476-1", "protein_name": "Complement decay-accelerating factor transmembrane isoform", "gene_name": "Cd55b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSSTWGYDPRAGAGDLVITTTAAGAVTIAVLLFQTVCGDCGPPPDIPNARPILGRHSKFAEQSKVAYSCNNGFKQVPDKSNIVVCLENGQWSSHETFCEKSCDTPERLSFASLKKEYFNMNFFPVGTIVEYECRPGFRKQPSLSGKSTCLEDLVWSPVAQFCKKKSCPNPKDLDNGHINIPTGILFGSEINFSCNPGYRLVGITSILCTIIGNTVDWDDEFPVCTEIFCPDPPKINNGIMRGESDSYKYSQVVIYSCDKGFILFGNSTIYCTVSKSDVGQWSSPPPQCIEESKVPIKKPVVNVPSTGIPSTPQKPTTESVPNPGDQPTPQKPSTVKVPATQHEPDTTTRTSTDKGESNSGGDRYIYGFVAVIAMIDSLIIVKTLWTILSPNRRSDFQGKERKDVSK", "length": 407 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63514-1", "protein_name": "C4b-binding protein alpha chain", "gene_name": "C4bpa", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLTAALWVAVFGKCGPPPDLPYALPASEMNQTDFESHTTLRYNCRPGYSRASSSQSLYCKPLGKWQINIACVKKSCRNPGDLQNGKVEVKTDFLFGSQIEFSCSEGYILIGSSTSYCEIQGKGVSWSDPLPECVIAKCGMPPDISNGKHNGREEEFFTYRSSVTYKCDPDFTLLGNASITCTVVNKTVGVWSPSPPTCERIICPWPKVLHGTINSGFKHTYKYKDSVRFVCQKGFVLRGSGVIHCEADGSWSPVPVCELNSCTDIPDIPNAALITSPRPRKEDVYPVGTVLRYICRPGYEPATRQPMTVICQKDLSWSMLRGCKEICCPVPDPKSVRVIQHEKAHPDNDCTYFFGDEVSYTCQNDIMLTATCKSDGTWHPRTPSCHQSCDFPPAIAHGRYTKSSSYYVRTQVTYECEEGYRLVGEATISCWYSQWTPAAPQCKALCRKPEIGNGVLSTNKDQYVETENVTIQCDSGFVMLGSQSITCSENGTWYPKVSRCEQEVPKDCEHVFAGKKLMQCLPNSNDVKMALEVYKLTLEIKQLQLQIDKAKHVDREL", "length": 558 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7TSY4-1", "protein_name": "Zona pellucida sperm-binding protein 3 receptor", "gene_name": "Zp3r", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAWSLHELWKTSHSTLFQVTLATVLMAPVLGDCGPPPSLPFASPISQLDEVSFPPGAVLKYTCHHGFKRTNSSHITCDENGSWVYTTFCARKRCKNPGELVNGKIEILSDLLVGLNIEFSCSEGYLLIGSATSRCEVQGKGVNWSDSLPECVIATCEPPPVINNGKHSGREEDLYTYGSMVIYSCDPSYTLFGNASIVCTVVNKTVGVWSPHPPACEKIVCHQPQIPKGELVPGFRHFHTYKDALEIRCKKGFALRGNSVIHCEANGEWFPSVPTCEPNGCIDIPDISYASWDGNRFPLENTAVFEIGTKLKYRCKPGYRANVHDVQIVTCQENLTWSSPSGCERVCCPTPNMEKIKIVSERRDFTGTCVYAYGDYVFYICSEGTYPMTTDGRSSCQADGKWDPAIPSCEADPSLQNHFALTFPNISETNVTNRTYLLENENATESFIKAVCPKPEIINGNLSVEKEIYAEMENITIQCDSGYDLVGSSNIICLENRTWYPDIPFCIMEGPEDCEIVNKGRQLLQCLSSPEDVQRALEVYKLSLEIERLEQQREKRTSVHRKAHYTKVDGPFRPFS", "length": 577 }, "evidence": [ { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z407-1", "protein_name": "CUB and sushi domain-containing protein 3", "gene_name": "CSMD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGIRKGESRAKESKPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFWNLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "length": 3707 }, "evidence": [ { "id": "RGD:1594530", "url": "https://alliancegenome.org/gene/RGD:1594530#orthology", "database": "AGR" }, { "id": "HGNC:19291", "url": "https://alliancegenome.org/gene/HGNC:19291#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-118#orthology", "database": "AGR" }, { "id": "MGI:2386403", "url": "https://alliancegenome.org/gene/MGI:2386403#orthology", "database": "AGR" }, { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80T79-3", "protein_name": "CUB and sushi domain-containing protein 3", "gene_name": "Csmd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGSRKGESRAKESKPREPGTRRCAKCGRLDFILKKKMGIKSGFTFWNLVFLLTLSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPGFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSPLTLTASIGELEEHIRTATGAIDVASTPADVTVSSVTAVTSHRLSEEQRVQVRSLSDSGLDPNTPEDQLSPHQADTQSTSRRPRNAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSLLNEGGIKTASNLCPDPGEPENGKRFGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMRSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPDSPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGPIPRCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDPGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSELPSTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRVGFSFGVGDTLTFSCSLGYRLEGSSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSLQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDSEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENEMLLKEVSGSLIPDGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGQERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTISVNTDYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRVLPSCHAPCGSRSTGSEGTVLSPNYPKNYSVDHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVFDGPTQQSPLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNDFAVGSLVLFECNPGYILHGSRAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKVGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIKLPIGFGVHLQFVNFSTETIHDYLEVRSGSSEISTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNISMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSAAFNVTSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHSWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTATCQSDGTWSNHNKTPRCVVVTCPSINSFTLDHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRTERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSGSETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGIPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDPGTPGHGSRQESDFRTKSTVRFACDTGYILYGSEERTCLSNGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCLEGYILSGPSVRQCTANGTWSGSLPNCTIISCGDPGIPANGLRYGDDFVVGQNVSYMCQPGYTIELNGSRVRTCTTNGTWSGVMPTCRAVTCSTPPQISNGRLEGTNFDWGFSISYICSAGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPSQGKREGKSFIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSDMELLLSGVYKSQEARLMLHIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIKGKDYGQFGLQRLGLNTSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "length": 3707 }, "evidence": [ { "id": "RGD:1594530", "url": "https://alliancegenome.org/gene/RGD:1594530#orthology", "database": "AGR" }, { "id": "HGNC:19291", "url": "https://alliancegenome.org/gene/HGNC:19291#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-118#orthology", "database": "AGR" }, { "id": "MGI:2386403", "url": "https://alliancegenome.org/gene/MGI:2386403#orthology", "database": "AGR" }, { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VYR4-1", "protein_name": "Furrowed, isoform C", "gene_name": "fw", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFCCNIPVDASVATSTSTSISTYPLQRATKRAMTPPNAMALIMLLLLALCAAGNGQICGPPAVPLNAKVRTITVDSQIAEAHYECDAGYELFGPSAVKCDRRTGWDRDLPFCGVNVAYRKPVNQSSYTRSGPASYANDGKPGNKNPDGQECSETQKEPSPWWRVDLLTPQAVHVVRITTRGCCGHQPLQDLEIRVGNSSADLQRNPLCAWYPGTLDEGVVKTFTCARPLVGQYVAIQLVGVEGSLSLCEVETFTNDEFSVDRCLSPKIGVDTVVTTFSKTCYDFHITKGESFDKAQAICKQTGGDLVHDFRGATSSYILSELERRKSELKPQLVWIGAQKEPGITSRTWKWVNGDVVQKPTWGKDQPNNYNGEQNCVVLDGGRNWLWNDVGCNLDYLHFICQHSPLSCGSPDAQQNTTVMGKKFTLGEKIQYTCPKGHSLLGQTERECRLDGTWSGSSPTCKYVDCGSLPELKFGSIHMSEERTSFGVVATYSCHENYTLIGNENRTCAMDGWSGKQPECLVDWCPDPQPIAGGDVRFNDKRAGSTATYVCEPGYVLVGEAIISCGLGGEWSSKTPSCRFVDCGAPARPNRGIAILLNGTTTVNSVVKYECDEDHWLDGQSELYCTREGKWSGEAPVCELVTCETPSVPSGSFVIGYDYNVHSKIQYNCDPGHIMHGTPVLECLDSGEWSADAPYCEYIDCGTILPIPYGSHKYVTNTTYVGSEVVFSCSQSHKLSGVLKRTCLESAVWSDASPKCEEIRCPEPKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTYKIGALAKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECGAPEGINNGKVVLATNATYYGAAVLYECNVNFKLNGVSRRLCTEHGNWSHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAKGRIMMGNDTRVCQKNGKWTGKSPTCRPVDCGRPLAIENGRVIVVNDSTLYGGSAEYHCIPNYNRIGQYLRKCTEDGAWSGKQPRCELATAEGQETSELGTGVGIGATVIVALLVIFGLIFLYRNKARPVKNTENVQAAETKDERNAAVMSYSTLEANNRMHMDNNPSATFNTFHGGAGGRSNGGGNPDANSNGERLNNNRSENIYDQIPNEQFYDAPYEMRTNDEVYEPEPVASNVITINGISVR", "length": 1174 }, "evidence": [ { "id": "RGD:1594530", "url": "https://alliancegenome.org/gene/RGD:1594530#orthology", "database": "AGR" }, { "id": "HGNC:19291", "url": "https://alliancegenome.org/gene/HGNC:19291#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-118#orthology", "database": "AGR" }, { "id": "MGI:2386403", "url": "https://alliancegenome.org/gene/MGI:2386403#orthology", "database": "AGR" }, { "id": "FB:FBgn0001083", "url": "https://alliancegenome.org/gene/FB:FBgn0001083#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNC7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNC7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1013, "end_pos": 1015, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1058, "end_pos": 1060, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1167, "end_pos": 1169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1423, "end_pos": 1425, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1478, "end_pos": 1480, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1596, "end_pos": 1598, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1668, "end_pos": 1670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1816, "end_pos": 1818, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1906, "end_pos": 1908, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2025, "end_pos": 2027, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2042, "end_pos": 2044, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2173, "end_pos": 2175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2178, "end_pos": 2180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2211, "end_pos": 2213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2382, "end_pos": 2384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2424, "end_pos": 2426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2602, "end_pos": 2604, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2633, "end_pos": 2635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2753, "end_pos": 2755, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2823, "end_pos": 2825, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2843, "end_pos": 2845, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2990, "end_pos": 2992, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3049, "end_pos": 3051, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3058, "end_pos": 3060, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3085, "end_pos": 3087, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3098, "end_pos": 3100, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3109, "end_pos": 3111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3167, "end_pos": 3169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3255, "end_pos": 3257, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3413, "end_pos": 3415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3420, "end_pos": 3422, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3518, "end_pos": 3520, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 611, "end_pos": 613, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 710, "end_pos": 712, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" }, { "start_pos": 853, "end_pos": 855, "annotation": "n_glycosylation_sequon" }, { "start_pos": 979, "end_pos": 981, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PNC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNC7" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 164, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PNC7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNC7" }, { "id": "PS50923", "database": "PROSITE", "url": 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"evidence": [ { "id": "XP_694358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694358" } ] } ], "protein_names": [ { "name": "Pentraxin-related protein PTX3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UT96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT96/entry#names_and_taxonomy" } ] }, { "name": "pentraxin-related protein PTX3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_694358", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694358" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_694358.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_694358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694358" } ] } ], "disease": [ { "disease_id": "DOID:0050073", "recommended_name": { "id": "DOID:0050073", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050073", "name": "invasive aspergillosis", "description": "An aspergillosis that is a serious fungal infection of the lung with pneumonia caused by Aspergillus, which spreads to other parts of the body through bloodstream in patients with acute leukemia and recipients of tissue transplants. Clinical symptoms include pulmonary nodules and hemorrhage." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050073" } ] }, { "disease_id": "DOID:0050153", "recommended_name": { "id": "DOID:0050153", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050153", "name": "pulmonary aspergilloma", "description": "An aspergillosis that presents as a clump of tangled mass of Aspergillus fungus fibres, blood clots, and white blood cells, which exists in the cavities of the lungs that develop in an area of previous lung disease or lung scarring." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050153", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050153" } ] }, { "disease_id": "DOID:0050848", "recommended_name": { "id": "DOID:0050848", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050848", "name": "obstructive sleep apnea", "description": "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep." }, "synonyms": [ { "id": "DOID:0050848", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050848", "name": "obstructive sleep apnea syndrome", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "obstructive sleep apnea syndrome", "description": "Cessation of air flow during sleep due to upper airway obstruction." }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "obstructive sleep apnea", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "obstructive sleep apnea syndrome", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "Apneas, obstructive sleep", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "OSAHS", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "apnea, obstructive sleep", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "obstructive sleep Apneas", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "sleep Apneas, obstructive", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "sleep apnea hypopnea syndrome", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "sleep apnea syndrome, obstructive", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "syndrome, obstructive sleep apnea", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "syndrome, sleep apnea, obstructive", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "syndrome, upper airway resistance, sleep apnea", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "upper airway resistance sleep apnea syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050848" } ] }, { "disease_id": "DOID:1003", "recommended_name": { "id": "DOID:1003", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1003", "name": "pelvic inflammatory disease", "description": "A female reproductive system disease that is characterized by an infection of the female reproductive organs." }, "synonyms": [ { "id": "DOID:1003", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1003", "name": "PID", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1003" } ] }, { "disease_id": "DOID:14115", "recommended_name": { "id": "DOID:14115", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14115", "name": "toxic shock syndrome", "description": "A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities." }, "synonyms": [ { "id": "DOID:14115", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14115", "name": "TSS", "description": "" }, { "id": "DOID:14115", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14115", "name": "toxic shock", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "14115", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14115" } ] }, { "disease_id": "DOID:1485", "recommended_name": { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs." }, "synonyms": [ { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "CF", "description": "" }, { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "mucoviscidosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis", "description": "Autosomal recessive disorder caused by pathogenic variants in the CFTR gene (cystic fibrosis transmembrane conductance regulator), which encodes a chloride and bicarbonate channel expressed in epithelial cells, and follow the diagnosis criteria. Diagnosis requires evidence of CFTR dysfunction, defined as a sweat chloride concentration of 60 mmol/L or greater, or identification of two CF-causing CFTR pathogenic variants, or an abnormal nasal potential difference measurement. CF is a progressive, multi-organ disease characterized by chronic obstructive lung disease with recurrent infections, exocrine pancreatic insufficiency, intestinal obstruction (including meconium ileus in neonates), male infertility due to obstructive azoospermia, hepatobiliary complications, and elevated sweat chloride concentrations." }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "CF", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis lung disease, modifier of", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "mucoviscidosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "pseudomonas aeruginosa, susceptibility to chronic infection by, in cystic fibrosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "fibrocystic disease of the pancreas", "description": "" }, { "id": "MIM:219700", "resource": "MIM", "url": "https://www.omim.org/entry/219700", "name": "Cystic fibrosis", "description": "Cystic fibrosis" } ], "unlinked_id_list": [], "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ] }, { "disease_id": "DOID:1883", "recommended_name": { "id": "DOID:1883", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1883", "name": "hepatitis C", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in hepatitis C virus (Hepacivirus hominis), which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice." }, "synonyms": [ { "id": "DOID:1883", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1883", "name": "NANBH", "description": "" }, { "id": "DOID:1883", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1883", "name": "Viral hepatitis C", "description": "" }, { "id": "DOID:1883", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1883", "name": "chronic hepatitis C", "description": "" }, { "id": "DOID:1883", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1883", "name": "hepatitis C infection", "description": "" }, { "id": "DOID:1883", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1883", "name": "hepatitis nonA nonB", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "hepatitis C virus infection", "description": "A viral infection caused by the hepatitis C virus." }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "Hepatitis C virus caused hepatitis", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "Hepatitis C virus hepatitis", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "NANBH", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "hepatitis C infection", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "hepatitis type C", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "non-A, non-B Hepatitis", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "chronic hepatitis C", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1883" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UT96", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT96" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ptx3b", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT96", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-385", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-385", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UT96", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UT96", "database": "AlphaFoldDB", "categories": [] }, { "id": "566001", "url": "https://www.ncbi.nlm.nih.gov/gene/566001", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566001", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566001", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UT96", "url": "https://www.orthodb.org/?gene=A0A8N7UT96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46943", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46943", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46943:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46943:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_694358", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694358", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UT96", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UT96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T5Q7", "url": "https://www.uniprot.org/uniprotkb/A0AB32T5Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T5Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T5Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-385", "url": "https://zfin.org/ZDB-GENE-081104-385", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MQRETNVHRMYAPGAVLALCLPCFLTGIVFSYEYGEDYSDSYYNEISNGDRVQSEGTQIPCPPQDLSRWDKLFIMLEDSQMKQNMLHWQTEDMVKKEMDSIRKDLHKLNNNKACVQASENTCKCISEQMNRNIKQVMEQLREAADSHQAQNNETLQQLIQLSRHQASRLAKLELGAGLGQVAVKSFSVYPKEQEASSADGGKLERALMAATADLQRVHAQLALFQRATVNRYLPSGCEMALLFPMRSKHIFAEVTPSMSMSLQTFTLCLWAKVTQALNKTVLFSYGSKINPQELQLLLSGRSLLLKVGGDTGLVEALGVVTDGQWGHFCATWSSKQGLADLWVNGESVARVSGVAEGHELPSDGFILLGQEISRSGIYRDLVSTVVFTGKMTGVNMWDHVLEAERIKEYANQDGSCDSRGNVIGWGISEIVPNGGAQYIN", "length": 440, "header": "tr|A0A8N7UT96-1|A0A8N7UT96_DANRE Isoform 1 of Pentraxin-related protein PTX3 isoform X1 OS=Danio rerio OX=7955 GN=ptx3b PE=4 SV=1 CANONICAL=A0A8N7UT96-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UT96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT96/entry#A0A8N7UT96-1", "sequence": { "sequence": "MQRETNVHRMYAPGAVLALCLPCFLTGIVFSYEYGEDYSDSYYNEISNGDRVQSEGTQIPCPPQDLSRWDKLFIMLEDSQMKQNMLHWQTEDMVKKEMDSIRKDLHKLNNNKACVQASENTCKCISEQMNRNIKQVMEQLREAADSHQAQNNETLQQLIQLSRHQASRLAKLELGAGLGQVAVKSFSVYPKEQEASSADGGKLERALMAATADLQRVHAQLALFQRATVNRYLPSGCEMALLFPMRSKHIFAEVTPSMSMSLQTFTLCLWAKVTQALNKTVLFSYGSKINPQELQLLLSGRSLLLKVGGDTGLVEALGVVTDGQWGHFCATWSSKQGLADLWVNGESVARVSGVAEGHELPSDGFILLGQEISRSGIYRDLVSTVVFTGKMTGVNMWDHVLEAERIKEYANQDGSCDSRGNVIGWGISEIVPNGGAQYIN", "length": 440, "header": "tr|A0A8N7UT96-1|A0A8N7UT96_DANRE Isoform 1 of Pentraxin-related protein PTX3 isoform X1 OS=Danio rerio OX=7955 GN=ptx3b PE=4 SV=1 CANONICAL=A0A8N7UT96-1" }, "locus": {} }, { "isoform_ac": "A0AB32T5Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT96/entry#A0AB32T5Q7-1", "sequence": { "sequence": "MLEDSQMKQNMLHWQTEDMVKKEMDSIRKDLHKLNNNKACVQASENTCKCISEQMNRNIKQVMEQLREAADSHQAQNNETLQQLIQLSRHQASRLAKLELGAGLGQVAVKSFSVYPKEQEASSADGGKLERALMAATADLQRVHAQLALFQRATVNRYLPSGCEMALLFPMRSKHIFAEVTPSMSMSLQTFTLCLWAKVTQALNKTVLFSYGSKINPQELQLLLSGRSLLLKVGGDTGLVEALGVVTDGQWGHFCATWSSKQGLADLWVNGESVARVSGVAEGHELPSDGFILLGQEISRSGIYRDLVSTVVFTGKMTGVNMWDHVLEAERIKEYANQDGSCDSRGNVIGWGISEIVPNGGAQYIN", "length": 366, "header": "tr|A0AB32T5Q7-1|A0A8N7UT96_DANRE Computationally mapped isoform of Pentraxin-related protein PTX3 isoform X1 OS=Danio rerio OX=7955 GN=ptx3b PE=4 SV=1 CANONICAL=A0A8N7UT96-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:566001", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566001", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LXB5-1", "protein_name": "Pentraxin-related protein PTX3", "gene_name": "Ptx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAETSYDYELMHVNLDNEIDNGLHPTEDPTPCDCRQEHSEWDKLFIMLENSQMREAMLLQATDDVLRGELQRLRAELGRLAGGMARPCSASGPADARLAQALEPLLQESRDANRRLARLEDAEARRHEATVPSLGAVLEELQRTRADLSAMQSWVARHWLPAGCETAIFFPMRSKKIFGSVHPVRPMKLESFSACIWVKATDVLNKTILFSYGTKWNPYEIQLYLSSQSLVFVVGGKENKLAADTVVSLGRWSHLCGTWSSEQGSMSLWANGELVATTLEMAKSHPVPEGGLLQIGQEKNGCCVGGGFDETLAFSGRITGFNIWDRVLSKEEIRASGGAESCHIRGNIVGWGVTEIQAHGGAQYVS", "length": 367 }, "evidence": [ { "id": "HGNC:9692", "url": "https://alliancegenome.org/gene/HGNC:9692#orthology", "database": "AGR" }, { "id": "MGI:104641", "url": "https://alliancegenome.org/gene/MGI:104641#orthology", "database": "AGR" }, { "id": "RGD:1593476", "url": "https://alliancegenome.org/gene/RGD:1593476#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-385", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-385#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A3KPN2-1", "protein_name": "Pentraxin-related protein PTX3", "gene_name": "ptx3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASKSMWTFLQTMCLVASLSMAVSDNYDDDIEVGFGHNYFNEIPDEDQLEDETPTPSPEPCKNTAFTKWDKLFTMLENSQMKENMLLQYADDIIKVELQNLRGEMIQFVAQYGGSCASAVESSVRRAGTQTESCLQNALDRAREVSADRYEQHDAVLQQLLAVSVNQAAQLDRLEKGCLKSGAFKNIQTRHLMQDVTEIENGGKLEKSLETISSELQSIREQLSLYTRSAFADKLPSGCDTGLLFPTRSSKAHAEVSPHGLLRTNAVTICLWVKPTQVFNKTILFSYSTTGNAYELQLVLSGQSASFTVDGESHLVEASGAVQEGQWGHLCASWSSQQGLASLWVNGQQAASSPGVAEGHELRSKGSILLGQEYGRHYKHLSTPDTFDAELAFTGKMTGVNMWDRVLDPKEISQQARLYGTACGIRGNVVAWGVSDIQPKEGVKLLY", "length": 447 }, "evidence": [ { "id": "HGNC:9692", "url": "https://alliancegenome.org/gene/HGNC:9692#orthology", "database": "AGR" }, { "id": "MGI:104641", "url": "https://alliancegenome.org/gene/MGI:104641#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P26022-1", "protein_name": "Pentraxin-related protein PTX3", "gene_name": "PTX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHLLAILFCALWSAVLAENSDDYDLMYVNLDNEIDNGLHPTEDPTPCACGQEHSEWDKLFIMLENSQMRERMLLQATDDVLRGELQRLREELGRLAESLARPCAPGAPAEARLTSALDELLQATRDAGRRLARMEGAEAQRPEEAGRALAAVLEELRQTRADLHAVQGWAARSWLPAGCETAILFPMRSKKIFGSVHPVRPMRLESFSACIWVKATDVLNKTILFSYGTKRNPYEIQLYLSYQSIVFVVGGEENKLVAEAMVSLGRWTHLCGTWNSEEGLTSLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYVS", "length": 381 }, "evidence": [ { "id": "HGNC:9692", "url": "https://alliancegenome.org/gene/HGNC:9692#orthology", "database": "AGR" }, { "id": "MGI:104641", "url": "https://alliancegenome.org/gene/MGI:104641#orthology", "database": "AGR" }, { "id": "RGD:1593476", "url": "https://alliancegenome.org/gene/RGD:1593476#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-385", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-385#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P48759-1", "protein_name": "Pentraxin-related protein PTX3", "gene_name": "Ptx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHLPAILLCALWSAVVAETSDDYELMYVNLDNEIDNGLHPTEDPTPCDCRQEHSEWDKLFIMLENSQMREGMLLQATDDVLRGELQRLRAELGRLAGGMARPCAAGGPADARLVRALEPLLQESRDASLRLARLEDAEARRPEATVPGLGAVLEELRRTRADLSAVQSWVARHWLPAGCETAIFFPMRSKKIFGSVHPVRPMKLESFSTCIWVKATDVLNKTILFSYGTKWNPYEIQLYLSSQSLVLVVGGKENKLAADTVVSLGRWSHLCGTWSSEQGSMSLWANGELVATTVEMAKSHSVPEGGLLQIGQEKNGCCVGGGFDESLAFSGRITGFNIWDRVLSEEEIRASGGVESCHIRGNVVGWGVTEIQAHGGAQYVS", "length": 381 }, "evidence": [ { "id": "HGNC:9692", "url": "https://alliancegenome.org/gene/HGNC:9692#orthology", "database": "AGR" }, { "id": "MGI:104641", "url": "https://alliancegenome.org/gene/MGI:104641#orthology", "database": "AGR" }, { "id": "RGD:1593476", "url": "https://alliancegenome.org/gene/RGD:1593476#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-385", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-385#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UT96", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT96" } ], "pmid": "" }, { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UT96", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT96" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UT96", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT96" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "complement component C1q complex binding", "id": "GO:0001849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001849", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UT96", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT96" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UT96", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT96" }, { "id": "PS51828", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51828" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pentraxin (PTX)", "eco_id": "ECO_0000259", "start_pos": 237, "end_pos": 440, "start_aa": "Cys", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 278, "end_pos": 280 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PKB3-1", "uniprot_ac": "A0A8M9PKB3", "uniprot_id": "A0A8M9PKB3_DANRE", "mass": { "chemical_mass": 21226.0, "monoisotopic_mass": 21226.0 }, "refseq": { "ac": "XP_021322696", "name": "myelin-associated glycoprotein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322696" }, "gene_names": [ { "name": "LOC101885065", "type": "recommended", "evidence": [ { "id": "A0A8M9PKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKB3" } ] }, { "name": "LOC101885065", "type": "synonym", "evidence": [ { "id": "XP_021322696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322696" } ] } ], "protein_names": [ { "name": "Myelin-associated glycoprotein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKB3/entry#names_and_taxonomy" } ] }, { "name": "myelin-associated glycoprotein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322696" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322696" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKB3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKB3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101885065", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKB3", "locus": {} } ], "crossref": [ { "id": "A0A8M9PKB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PKB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "101885065", "url": "https://www.ncbi.nlm.nih.gov/gene/101885065", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056386", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056386", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885065", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885065", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PKB3", "url": "https://www.orthodb.org/?gene=A0A8M9PKB3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46013", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46013", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46013:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46013:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24518", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24518", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322696", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322696", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PKB3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PKB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T748", "url": "https://www.uniprot.org/uniprotkb/A0AB32T748", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T748-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T748-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSANLLPGVWILTSLLFSGIHAADWIVDVPSDPVYAPLGSSVVLQCRYDYPEDPEQGKPHRVKSEMWCLNQSHCITQRYVYHSAGIFPEPSYQGRVKYFGQTGSKNCSLMISDLRSADSGVYVFRFITDHQNAKLPGQRGVNLQVTQLMTAKSASSSTIGIVFGVIVIVIIIACILLFIRNKSRSQRSRSL", "length": 191, "header": "tr|A0A8M9PKB3-1|A0A8M9PKB3_DANRE Isoform 1 of Myelin-associated glycoprotein isoform X1 OS=Danio rerio OX=7955 GN=LOC101885065 PE=4 SV=1 CANONICAL=A0A8M9PKB3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PKB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKB3/entry#A0A8M9PKB3-1", "sequence": { "sequence": "MSANLLPGVWILTSLLFSGIHAADWIVDVPSDPVYAPLGSSVVLQCRYDYPEDPEQGKPHRVKSEMWCLNQSHCITQRYVYHSAGIFPEPSYQGRVKYFGQTGSKNCSLMISDLRSADSGVYVFRFITDHQNAKLPGQRGVNLQVTQLMTAKSASSSTIGIVFGVIVIVIIIACILLFIRNKSRSQRSRSL", "length": 191, "header": "tr|A0A8M9PKB3-1|A0A8M9PKB3_DANRE Isoform 1 of Myelin-associated glycoprotein isoform X1 OS=Danio rerio OX=7955 GN=LOC101885065 PE=4 SV=1 CANONICAL=A0A8M9PKB3-1" }, "locus": {} }, { "isoform_ac": "A0AB32T748-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKB3/entry#A0AB32T748-1", "sequence": { "sequence": "MSANLLPGVWILTSLLFSGIHAADWIVDVPSDPVYAPLGSSVVLQCRYDYPEDPEQGKPHRVKSEMWCLNQSHCITQRYVYHSAGIFPEPSYQGRVKYFGQTGSKNCSLMISDLRSADSGVYVFRFITDHQNAKLPGQRGVNLQVTQLMTGARGQDHFEQGIDAVLQWFSNCGTCTTSGTPASF", "length": 184, "header": "tr|A0AB32T748-1|A0A8M9PKB3_DANRE Computationally mapped isoform of Myelin-associated glycoprotein isoform X1 OS=Danio rerio OX=7955 GN=LOC101885065 PE=4 SV=1 CANONICAL=A0A8M9PKB3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885065", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885065", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PKB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKB3" }, { "id": "SM00409", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00409" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Immunoglobulin", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 146, "start_aa": "Ser", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 181, "end_pos": 183 }, { "start_pos": 70, "end_pos": 72 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UR00-1", "uniprot_ac": "A0A8N7UR00", "uniprot_id": "A0A8N7UR00_DANRE", "mass": { "chemical_mass": 42091.0, "monoisotopic_mass": 42091.0 }, "refseq": { "ac": "XP_690325", "name": "neuromedin-B receptor isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690325" }, "gene_names": [ { "name": "nmbr", "type": "recommended", "evidence": [ { "id": "A0A8N7UR00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00" } ] }, { "name": "nmbr", "type": "synonym", "evidence": [ { "id": "XP_690325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690325" } ] } ], "protein_names": [ { "name": "Neuromedin-B receptor", "type": "recommended", "evidence": [ { "id": "A0A8N7UR00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00/entry#names_and_taxonomy" } ] }, { "name": "Neuromedin-B-preferring bombesin receptor", "type": "synonym", "evidence": [ { "id": "A0A8N7UR00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00/entry#names_and_taxonomy" } ] }, { "name": "neuromedin-B receptor isoform X2", "type": "synonym", "evidence": [ { "id": "XP_690325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690325" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_690325.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_690325", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690325" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR00", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nmbr", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041014-369", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-369", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UR00", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UR00", "database": "AlphaFoldDB", "categories": [] }, { "id": "561834", "url": "https://www.ncbi.nlm.nih.gov/gene/561834", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001556", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001556", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561834", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561834", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UR00", "url": "https://www.orthodb.org/?gene=A0A8N7UR00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45695:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45695:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_690325", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690325", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UR00", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UR00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T8M1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8M1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T8M1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8M1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041014-369", "url": "https://zfin.org/ZDB-GENE-041014-369", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDHTFSEDTAVYENFTEDWTSDGGETVHFIIQCVIPSVYILIITVGLLGNITLVKIFITTSAMRSVPNIFISSLAVGDLLLLVTCVPVDAFRYFYEEWIFGTVACKMIPVIQLTSVGVSVFTLTALSADRHKAIVNPMDIQSSSAVFWTCLKAITIWVVSVLLAIPEAVFSQVVHMPDKNTTFTACVPYPLSNEMHPKIHSIMIFLVYFLIPLSIISVYYYHIARTLIKSAHDMPGEISEHSKRQTETRKRLAKIVLVFVGLFALCWFPNHVLYMYRSFNYRQIDSSLSHLIITLVARVLSFSSSCVNPFALYLLSESFRRHFNNQLLCRQRKYQERNTSYLQSTSAIRMTSIRKSTPAVANGHGQKQGVCI", "length": 372, "header": "tr|A0A8N7UR00-1|A0A8N7UR00_DANRE Isoform 1 of Neuromedin-B receptor OS=Danio rerio OX=7955 GN=nmbr PE=3 SV=1 CANONICAL=A0A8N7UR00-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UR00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00/entry#A0A8N7UR00-1", "sequence": { "sequence": "MDHTFSEDTAVYENFTEDWTSDGGETVHFIIQCVIPSVYILIITVGLLGNITLVKIFITTSAMRSVPNIFISSLAVGDLLLLVTCVPVDAFRYFYEEWIFGTVACKMIPVIQLTSVGVSVFTLTALSADRHKAIVNPMDIQSSSAVFWTCLKAITIWVVSVLLAIPEAVFSQVVHMPDKNTTFTACVPYPLSNEMHPKIHSIMIFLVYFLIPLSIISVYYYHIARTLIKSAHDMPGEISEHSKRQTETRKRLAKIVLVFVGLFALCWFPNHVLYMYRSFNYRQIDSSLSHLIITLVARVLSFSSSCVNPFALYLLSESFRRHFNNQLLCRQRKYQERNTSYLQSTSAIRMTSIRKSTPAVANGHGQKQGVCI", "length": 372, "header": "tr|A0A8N7UR00-1|A0A8N7UR00_DANRE Isoform 1 of Neuromedin-B receptor OS=Danio rerio OX=7955 GN=nmbr PE=3 SV=1 CANONICAL=A0A8N7UR00-1" }, "locus": {} }, { "isoform_ac": "A0AB32T8M1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00/entry#A0AB32T8M1-1", "sequence": { "sequence": "MDHTFSEDTAVYENFTEDWTSDGGETVHFIIQCVIPSVYILIITVGLLGNITLVKIFITTSAMRSVPNIFISSLAVGDLLLLVTCVPVDAFRYFYEEWIFGTVACKMIPVIQLTSVGVSVFTLTALSADRHKAIVNPMDIQSSSAVFWTCLKAITIWVVSVLLAIPEAVFSQVVHMPDKNTTFTACVPYPLSNEMHPKIHSIMIFLVYFLIPLSIISVYYYHIARTLIKSAHDMPDGNEEASGQDCSGIRGPLCPVLVPQPRSLHVPLIQLSADRLLAVTPHHYACGTRAELLQLLRQPVCLVSAERELPTPLQQPAAV", "length": 319, "header": "tr|A0AB32T8M1-1|A0A8N7UR00_DANRE Computationally mapped isoform of Neuromedin-B receptor OS=Danio rerio OX=7955 GN=nmbr PE=3 SV=1 CANONICAL=A0A8N7UR00-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561834", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561834", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1ZAX0-1", "protein_name": "Neuropeptide CCHamide-1 receptor", "gene_name": "CCHa1-R", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIANLVSMETDLAMNIGLDTSGEAPTALPPMPNVTETLWDLAMVVSQSTQWPLLDTGSSENFSELVTTETPYVPYGRRPETYIVPILFALIFVVGVLGNGTLIVVFLSVRQMRNVPNTYILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVSVFTLTALSGDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNLKHLGINEKSIVICYPYPEEWGINYAKSMVLLHFLVYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVRQVRARRKVAVTVLAFVVIFGICFLPYHVFFLWFYFWPTAQDDYNAFWHVLRIVAYCMSFANSCANPVALYFVSGAFRKHFNRYLFCRGASGRRKKRGQHDTFCMHRDTSLTSTASKRFQSRHSCYQSTIRSCRLQETTITTLPNGGNQNGANISAVELALPVLQAPGHNEAHAPPSYGFLPLNEIVQQTRSSPAKFQESLLN", "length": 499 }, "evidence": [ { "id": "RGD:3181", "url": "https://alliancegenome.org/gene/RGD:3181#orthology", "database": "AGR" }, { "id": "HGNC:7843", "url": "https://alliancegenome.org/gene/HGNC:7843#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-369", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-369#orthology", "database": "AGR" }, { "id": "MGI:1100525", "url": "https://alliancegenome.org/gene/MGI:1100525#orthology", "database": "AGR" }, { "id": "FB:FBgn0050106", "url": "https://alliancegenome.org/gene/FB:FBgn0050106#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O54798-1", "protein_name": "Bombesin receptor subtype-3", "gene_name": "Brs3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQRQSQSPNQTLISITNDTETSSSVVSNDTTHKGWTGDNSPGIEALCAIYITYAGIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGKVGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPPNAILKTCAKAGGIWIVSMIFALPEAIFSNVYTFQDPNRNVTFESCNSYPISERLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIAKTVLVLVALFALCWLPNHLLYLYHSFTYESYANHSDVPFVIIIFSRVLAFSNSCVNPFALYWLSKTFQQHFKAQLCCLKAEQPEPPLGDIPLNNLTVMGRVPATGSAHVSEISVTLFSGSSAKKGEDKV", "length": 399 }, "evidence": [ { "id": "FB:FBgn0050106", "url": "https://alliancegenome.org/gene/FB:FBgn0050106#orthology", "database": "AGR" }, { "id": "FB:FBgn0033058", "url": "https://alliancegenome.org/gene/FB:FBgn0033058#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O54799-1", "protein_name": "Neuromedin-B receptor", "gene_name": "Nmbr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPRSLSNLSFPTEANESELVPEVWEKDFLPDSDGTTAELVIRCVIPSLYLIIISVGLLGNIMLVKIFLTNSAMRNVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWVFGKLGCKLIPAIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGVLLWTSLKAVGIWVVSVLLAVPEAVFSEVARIGSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFVFCWFPNHVLYLYRSFNYKEIDPSLGHMIVTLVARVLSFSNSCVNPFALYLLSESFRKHFNSQLCCGRKSYPERSTSYLLSSSAVRMTSLKSNTKNVVTNSVLLNGHSTKQEIAL", "length": 390 }, "evidence": [ { "id": "RGD:3181", "url": "https://alliancegenome.org/gene/RGD:3181#orthology", "database": "AGR" }, { "id": "HGNC:7843", "url": "https://alliancegenome.org/gene/HGNC:7843#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-369", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-369#orthology", "database": "AGR" }, { "id": "MGI:1100525", "url": "https://alliancegenome.org/gene/MGI:1100525#orthology", "database": "AGR" }, { "id": "FB:FBgn0050106", "url": "https://alliancegenome.org/gene/FB:FBgn0050106#orthology", "database": "AGR" }, { "id": "FB:FBgn0033058", "url": "https://alliancegenome.org/gene/FB:FBgn0033058#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P21729-1", "protein_name": "Gastrin-releasing peptide receptor", "gene_name": "Grpr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPNNCSHLNLDVDPFLSCNDTFNQSLSPPKMDNWFHPGFIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLAIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLMNRSHSTGRSTTCMTSFKSTNPSATFSLINRNICHEGYV", "length": 384 }, "evidence": [ { "id": "FB:FBgn0050106", "url": "https://alliancegenome.org/gene/FB:FBgn0050106#orthology", "database": "AGR" }, { "id": "FB:FBgn0033058", "url": "https://alliancegenome.org/gene/FB:FBgn0033058#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P24053-1", "protein_name": "Neuromedin-B receptor", "gene_name": "Nmbr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPRSLPNLSLPTEASESELEPEVWENDFLPDSDGTTAELVIRCVIPSLYLIIISVGLLGNIMLVKIFLTNSTMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWVFGKLGCKLIPAIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGVVLWTSLKAVGIWVVSVLLAVPEAVFSEVARIGSSDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLVIISIYYYHIAKTLIRSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFVFCWFPNHILYLYRSFNYKEIDPSLGHMIVTLVARVLSFSNSCVNPFALYLLSESFRKHFNSQLCCGQKSYPERSTSYLLSSSAVRMTSLKSNAKNVVTNSVLLNGHSTKQEIAL", "length": 390 }, "evidence": [ { "id": "RGD:3181", "url": "https://alliancegenome.org/gene/RGD:3181#orthology", "database": "AGR" }, { "id": "HGNC:7843", "url": "https://alliancegenome.org/gene/HGNC:7843#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-369", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-369#orthology", "database": "AGR" }, { "id": "MGI:1100525", "url": "https://alliancegenome.org/gene/MGI:1100525#orthology", "database": "AGR" }, { "id": "FB:FBgn0050106", "url": "https://alliancegenome.org/gene/FB:FBgn0050106#orthology", "database": "AGR" }, { "id": "FB:FBgn0033058", "url": "https://alliancegenome.org/gene/FB:FBgn0033058#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P28336-1", "protein_name": "Neuromedin-B receptor", "gene_name": "NMBR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSKSLSNLSVTTGANESGSVPEGWERDFLPASDGTTTELVIRCVIPSLYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGHSMKQEMAL", "length": 390 }, "evidence": [ { "id": "RGD:3181", "url": "https://alliancegenome.org/gene/RGD:3181#orthology", "database": "AGR" }, { "id": "HGNC:7843", "url": "https://alliancegenome.org/gene/HGNC:7843#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-369", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-369#orthology", "database": "AGR" }, { "id": "MGI:1100525", "url": "https://alliancegenome.org/gene/MGI:1100525#orthology", "database": "AGR" }, { "id": "FB:FBgn0050106", "url": "https://alliancegenome.org/gene/FB:FBgn0050106#orthology", "database": "AGR" }, { "id": "FB:FBgn0033058", "url": "https://alliancegenome.org/gene/FB:FBgn0033058#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P30550-1", "protein_name": "Gastrin-releasing peptide receptor", "gene_name": "GRPR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALNDCFLLNLEVDHFMHCNISSHSADLPVNDDWSHPGILYVIPAVYGVIILIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLITCAPVDASRYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAAFIWIISMLLAIPEAVFSDLHPFHEESTNQTFISCAPYPHSNELHPKIHSMASFLVFYVIPLSIISVYYYFIAKNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFVTSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPGLIIRSHSTGRSTTCMTSLKSTNPSVATFSLINGNICHERYV", "length": 384 }, "evidence": [ { "id": "FB:FBgn0050106", "url": "https://alliancegenome.org/gene/FB:FBgn0050106#orthology", "database": "AGR" }, { "id": "FB:FBgn0033058", "url": "https://alliancegenome.org/gene/FB:FBgn0033058#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P32247-1", "protein_name": "Bombesin receptor subtype-3", "gene_name": "BRS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQRQPHSPNQTLISITNDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFALPEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQTYVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADTSLTTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF", "length": 399 }, "evidence": [ { "id": "FB:FBgn0050106", "url": "https://alliancegenome.org/gene/FB:FBgn0050106#orthology", "database": "AGR" }, { "id": "FB:FBgn0033058", "url": "https://alliancegenome.org/gene/FB:FBgn0033058#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P52500-1", "protein_name": "Gastrin-releasing peptide receptor", "gene_name": "Grpr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPNNCSHLNLEVDPFLSCNNTFNQTLNPPKMDNWFHPGIIYVIPAVYGLIIVIGLIGNITLIKIFCTVKSMRNVPNLFISSLALGDLLLLVTCAPVDASKYLADRWLFGRIGCKLIPFIQLTSVGVSVFTLTALSADRYKAIVRPMDIQASHALMKICLKAALIWIVSMLLAIPEAVFSDLHPFHVKDTNQTFISCAPYPHSNELHPKIHSMASFLVFYIIPLSIISVYYYFIARNLIQSAYNLPVEGNIHVKKQIESRKRLAKTVLVFVGLFAFCWLPNHVIYLYRSYHYSEVDTSMLHFITSICARLLAFTNSCVNPFALYLLSKSFRKQFNTQLLCCQPSLLNRSHSTGRSTTCMTSFKSTNPSATFSLINGNICHEGYV", "length": 384 }, "evidence": [ { "id": "FB:FBgn0050106", "url": "https://alliancegenome.org/gene/FB:FBgn0050106#orthology", "database": "AGR" }, { "id": "FB:FBgn0033058", "url": "https://alliancegenome.org/gene/FB:FBgn0033058#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4V622-1", "protein_name": "Neuropeptide CCHamide-2 receptor", "gene_name": "CCHa2-R", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYASLMDVGQTLAARLADSDGNGANDSGLLATGQGLEQEQEGLALDMGHNASADGGIVPYVPVLDRPETYIVTVLYTLIFIVGVLGNGTLVIIFFRHRSMRNIPNTYILSLALADLLVILVCVPVATIVYTQESWPFERNMCRISEFFKDISIGVSVFTLTALSGERYCAIVNPLRKLQTKPLTVFTAVMIWILAILLGMPSVLFSDIKSYPVFTATGNMTIEVCSPFRDPEYAKFMVAGKALVYYLLPLSIIGALYIMMAKRLHMSARNMPGEQQSMQSRTQARARLHVARMVVAFVVVFFICFFPYHVFELWYHFYPTAEEDFDEFWNVLRIVGFCTSFLNSCVNPVALYCVSGVFRQHFNRYLCCICVKRQPHLRQHSTATGMMDNTSVMSMRRSTYVGGTAGNLRASLHRNSNHGVGGAGGGVGGGVGSGRVGSFHRQDSMPLQHGNAHGGGAGGGSSGLGAGGRTAAVSEKSFINRYESGVMRY", "length": 489 }, "evidence": [ { "id": "RGD:3181", "url": "https://alliancegenome.org/gene/RGD:3181#orthology", "database": "AGR" }, { "id": "HGNC:7843", "url": "https://alliancegenome.org/gene/HGNC:7843#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041014-369", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041014-369#orthology", "database": "AGR" }, { "id": "MGI:1100525", "url": "https://alliancegenome.org/gene/MGI:1100525#orthology", "database": "AGR" }, { "id": "FB:FBgn0033058", "url": "https://alliancegenome.org/gene/FB:FBgn0033058#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8K418-1", "protein_name": "Bombesin receptor subtype-3", "gene_name": "Brs3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQRQPQSPNQTLISITNDTETSSSAVSNDTTPKGWTGDNSPGIEALCAIYITYAVIISVGILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGKVGCKVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCAKAGGIWIMAMIFALPEAIFSNVYTFQDPNRNVTFESCNSYPISERLLQEIHSLLCFLVFYIIPLSIISVYYSLIARTLYKSTLNIPTEEQSHARKQIESRKRIAKTVLVLVALFALCWLPNHLLYLYHSFTYESYAEPSDVPFVVTIFSRVLAFSNSCVNPFALYWLSKTFQKHFKAQLCCFKAEQPEPPLGDTPLNNLTVMGRVPATGSAHVSEISVTLFSGSTAKKGEDKV", "length": 399 }, "evidence": [ { "id": "FB:FBgn0050106", "url": "https://alliancegenome.org/gene/FB:FBgn0050106#orthology", "database": "AGR" }, { "id": "FB:FBgn0033058", "url": "https://alliancegenome.org/gene/FB:FBgn0033058#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR00", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled peptide receptor activity", "id": "GO:0008528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008528", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR00", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00" } ], "pmid": "" }, { "name": "neuropeptide receptor activity", "id": "GO:0008188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008188", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR00", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR00", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UR00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR00" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 312, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 180, "end_pos": 182 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 50, "end_pos": 52 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PQ65-1", "uniprot_ac": "A0A8M9PQ65", "uniprot_id": "A0A8M9PQ65_DANRE", "mass": { "chemical_mass": 33781.0, "monoisotopic_mass": 33781.0 }, "refseq": { "ac": "XP_021324401", "name": "probable methyltransferase-like protein 24 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324401" }, "gene_names": [ { "name": "mettl24", "type": "recommended", "evidence": [ { "id": "A0A8M9PQ65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65" } ] }, { "name": "mettl24", "type": "synonym", "evidence": [ { "id": "XP_021324401", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324401" } ] } ], "protein_names": [ { "name": "Probable methyltransferase-like protein 24 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PQ65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65/entry#names_and_taxonomy" } ] }, { "name": "probable methyltransferase-like protein 24 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021324401", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324401" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324401" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQ65", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mettl24", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070424-138", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-138", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PQ65", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PQ65", "database": "AlphaFoldDB", "categories": [] }, { "id": "100000285", "url": "https://www.ncbi.nlm.nih.gov/gene/100000285", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025714", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025714", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100000285", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000285", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PQ65", "url": "https://www.orthodb.org/?gene=A0A8M9PQ65", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32026", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32026", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32026:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32026:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13383", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13383", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021324401", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324401", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PCE8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PI21", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI21", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PI21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PI21-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQ65", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQ65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TA94", "url": "https://www.uniprot.org/uniprotkb/A0AB32TA94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TA94-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TA94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6S9", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6S9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6S9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6S9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6T4", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6T4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6T9", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6T9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6T9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6T9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6U7", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6U7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6U7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6U7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070424-138", "url": "https://zfin.org/ZDB-GENE-070424-138", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVTDGDGSRMCSCMKRMRTRKGLLLRVCGLLTLLCVCVSLTAWSSTHTLDKHAAEFRNEEGSDLKSTSTCCSPHKHHRPVLRWRIDLEPWANGMPALQEEAQRFLSYISTPQVSCDAHREDYGPWALCLDQRFSLAQRIRSKHCRVYSLRLGSSSADVVERALASSGCDVHCFDPSISSAHLQQQQHLWLHRLSVDWRDPNPAVPPHRAHSNSRKLKNILNHFGHRQVDVLKVDVAGAEWALLGSLPPLPQLQRPQQTTHHPAPKPPERQRLLQPGLGQHSLPAAGLTRETRHSGAVYIR", "length": 300, "header": "tr|A0A8M9PQ65-1|A0A8M9PQ65_DANRE Isoform 1 of Probable methyltransferase-like protein 24 isoform X1 OS=Danio rerio OX=7955 GN=mettl24 PE=4 SV=1 CANONICAL=A0A8M9PQ65-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PCE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65/entry#A0A8M9PCE8-1", "sequence": { "sequence": "MVTDGDGSRMCSCMKRMRTRKGLLLRVCGLLTLLCVCVSLTAWSSTHTLDKHAAEFRNEEGSDLKSTSTCCSPHKHHRPVLRWRIDLEPWANGMPALQEEAQRFLSYISTPQVSCDAHREDYGPWALCLDQRFSLAQRIRSKHCRVYSLRLGSSSADVVERALASSGCDVHCFDPSISSAHLQQQQHLWLHRLSVDWRDPNPAVPPHRAHSNSRKLKNILNHFGHRQIAHERTSHLFCRPDITAEAEKSSKTAALMHESISDA", "length": 263, "header": "tr|A0A8M9PCE8-1|A0A8M9PQ65_DANRE Computationally mapped isoform of Probable methyltransferase-like protein 24 isoform X1 OS=Danio rerio OX=7955 GN=mettl24 PE=4 SV=1 CANONICAL=A0A8M9PQ65-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PI21-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65/entry#A0A8M9PI21-1", "sequence": { "sequence": "MTEVLRWRIDLEPWANGMPALQEEAQRFLSYISTPQVSCDAHREDYGPWALCLDQRFSLAQRIRSKHCRVYSLRLGSSSADVVERALASSGCDVHCFDPSISSAHLQQQQHLWLHRLSVDWRDPNPAVPPHRAHSNSRKLKNILNHFGHRQVDVLKVDVAGAEWALLGSLPPLPQLQRPQQTTHHPAPKPPERQRLLQPGLGQHSLPAAGLTRETRHSGAVYIR", "length": 224, "header": "tr|A0A8M9PI21-1|A0A8M9PQ65_DANRE Computationally mapped isoform of Probable methyltransferase-like protein 24 isoform X1 OS=Danio rerio OX=7955 GN=mettl24 PE=4 SV=1 CANONICAL=A0A8M9PQ65-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PQ65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65/entry#A0A8M9PQ65-1", "sequence": { "sequence": "MVTDGDGSRMCSCMKRMRTRKGLLLRVCGLLTLLCVCVSLTAWSSTHTLDKHAAEFRNEEGSDLKSTSTCCSPHKHHRPVLRWRIDLEPWANGMPALQEEAQRFLSYISTPQVSCDAHREDYGPWALCLDQRFSLAQRIRSKHCRVYSLRLGSSSADVVERALASSGCDVHCFDPSISSAHLQQQQHLWLHRLSVDWRDPNPAVPPHRAHSNSRKLKNILNHFGHRQVDVLKVDVAGAEWALLGSLPPLPQLQRPQQTTHHPAPKPPERQRLLQPGLGQHSLPAAGLTRETRHSGAVYIR", "length": 300, "header": "tr|A0A8M9PQ65-1|A0A8M9PQ65_DANRE Isoform 1 of Probable methyltransferase-like protein 24 isoform X1 OS=Danio rerio OX=7955 GN=mettl24 PE=4 SV=1 CANONICAL=A0A8M9PQ65-1" }, "locus": {} }, { "isoform_ac": "A0AB32TA94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65/entry#A0AB32TA94-1", "sequence": { "sequence": "MVTDGDGSRMCSCMKRMRTRKGLLLRVCGLLTLLCVCVSLTAWSSTHTLDKHAAEFRNEEGSDLKSTSTCCSPHKHHRPVLRWRIDLEPWANGMPALQEEAQRFLSYISTPQVSCDAHREDYGPWALCLDQRFSLAQRIRSKHCRVYSLRLGSSSADVVERALASSGCDVHCFDPSISSAHLQQQQHLWLHRLSVDWRDPNPAVPPHRAHSNSRKLKNILNHFGHRQVMQ", "length": 230, "header": "tr|A0AB32TA94-1|A0A8M9PQ65_DANRE Computationally mapped isoform of Probable methyltransferase-like protein 24 isoform X1 OS=Danio rerio OX=7955 GN=mettl24 PE=4 SV=1 CANONICAL=A0A8M9PQ65-1" }, "locus": {} }, { "isoform_ac": "A0AC58I6S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65/entry#A0AC58I6S9-1", "sequence": { "sequence": "MTEVLRWRIDLEPWANGMPALQEEAQRFLSYISTPQVSCDAHREDYGPWALCLDQRFSLAQRIRSKHCRVYSLRLGSSSADVVERALASSGCDVHCFDPSISSAHLQQQQHLWLHRLSVDWRDPNPAVPPHRAHSNSRKLKNILNHFGHRQVMQ", "length": 154, "header": "tr|A0AC58I6S9-1|A0AC58I6S9_DANRE Computationally mapped isoform of Probable methyltransferase-like protein 24 isoform X7 OS=Danio rerio OX=7955 GN=mettl24 PE=4 SV=1 CANONICAL=A0A8M9PQ65-1" }, "locus": {} }, { "isoform_ac": "A0AC58I6T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65/entry#A0AC58I6T4-1", "sequence": { "sequence": "MGCLLYRRRRSDSSHTSPHHRLGSSSADVVERALASSGCDVHCFDPSISSAHLQQQQHLWLHRLSVDWRDPNPAVPPHRAHSNSRKLKNILNHFGHRQVMQ", "length": 101, "header": "tr|A0AC58I6T4-1|A0AC58I6T4_DANRE Computationally mapped isoform of Probable methyltransferase-like protein 24 isoform X8 OS=Danio rerio OX=7955 GN=mettl24 PE=4 SV=1 CANONICAL=A0A8M9PQ65-1" }, "locus": {} }, { "isoform_ac": "A0AC58I6T9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65/entry#A0AC58I6T9-1", "sequence": { "sequence": "MTEVLRWRIDLEPWANGMPALQEEAQRFLSYISTPQVSCDAHREDYGPWALCLDQRFSLAQRIRSKHCRVYSLRLGSSSADVVERALASSGCDVHCFDPSISSAHLQQQQHLWLHRLSVDWRDPNPAVPPHRAHSNSRKLKNILNHFGHRQIAHERTSHLFCRPDITAEAEKSSKTAALMHESISDA", "length": 187, "header": "tr|A0AC58I6T9-1|A0AC58I6T9_DANRE Computationally mapped isoform of Probable methyltransferase-like protein 24 isoform X5 OS=Danio rerio OX=7955 GN=mettl24 PE=4 SV=1 CANONICAL=A0A8M9PQ65-1" }, "locus": {} }, { "isoform_ac": "A0AC58I6U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65/entry#A0AC58I6U7-1", "sequence": { "sequence": "MGCLLYRRRRSDSSHTSPHHRLGSSSADVVERALASSGCDVHCFDPSISSAHLQQQQHLWLHRLSVDWRDPNPAVPPHRAHSNSRKLKNILNHFGHRQVDVLKVDVAGAEWALLGSLPPLPQLQRPQQTTHHPAPKPPERQRLLQPGLGQHSLPAAGLTRETRHSGAVYIR", "length": 171, "header": "tr|A0AC58I6U7-1|A0AC58I6U7_DANRE Computationally mapped isoform of Probable methyltransferase-like protein 24 isoform X6 OS=Danio rerio OX=7955 GN=mettl24 PE=4 SV=1 CANONICAL=A0A8M9PQ65-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100000285", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000285", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5BK01-1", "protein_name": "Probable methyltransferase-like protein 24", "gene_name": "Mettl24", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGTAKPPGRGCGALPRWLLGAALLLGLRLCMELRHAGSGPPGRRDLRGPPRTHLLPAPGPLRGTRRRQVTYVRSGRRALPRGGVSTTPPEPSCCAQLGLPSRKGPRWHIELQPWAGPSRSLDEEASRFLNYIGTTQIACDRMGTNSVATDSGPALKPWLVCLDDRFGLAHQIRTKQCRLYSLGLGSDDTHFEVSMANGGCEVHRFDPSVRSAHVLQSQRLWHHRLSIDWRDPHPAVAAQKPYSNTRKLGSILNEFGHHKIDVLKADLESAEWKVLENLILEDVLEQIGQLIFEIHLHWPGFEVSGSESSVVRFWYSLLKELERKDFRLFHTYKDLSKPQLFLKKDIFNASSCYTLSWVNTRWR", "length": 363 }, "evidence": [ { "id": "HGNC:21566", "url": "https://alliancegenome.org/gene/HGNC:21566#orthology", "database": "AGR" }, { "id": "RGD:1564857", "url": "https://alliancegenome.org/gene/RGD:1564857#orthology", "database": "AGR" }, { "id": "MGI:3045338", "url": "https://alliancegenome.org/gene/MGI:3045338#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-138", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-138#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JXM2-1", "protein_name": "Probable methyltransferase-like protein 24", "gene_name": "METTL24", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARERPPGRGCGVLRRCLLGAVLLFGLRLCAELRRAGPGSPTRSAPPGPAWRPPGPHLPPAPGQPRGASRRQVTYVRSGRRAPPGGGGSGTPEPGCCAPRGRPRRKGPRWHIDLQPWAGSAQSLDEEAWRFLRYISTTQIACNHMNTDSLATDSSPTHKPWSVCLDDRFNLAHQIRNKQCRLYSLGLGSDDTHFEVSMANNGCEVHRFDPSVKSAHILESQHLWYHRLSIDWRDPHPAVAAQKPHSNTRKLGSILNEFGHHKIDVLKADLESAEWKVLENLILEDVLEQIGQLIFEIHLHWPGFEVSGSDSSVVRFWYSLLKELEQKDFRLFHSYKDLSKPQLFLKKDIFNASSCYTLSWVNTRWK", "length": 366 }, "evidence": [ { "id": "HGNC:21566", "url": "https://alliancegenome.org/gene/HGNC:21566#orthology", "database": "AGR" }, { "id": "RGD:1564857", "url": "https://alliancegenome.org/gene/RGD:1564857#orthology", "database": "AGR" }, { "id": "MGI:3045338", "url": "https://alliancegenome.org/gene/MGI:3045338#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-138", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-138#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CCB5-1", "protein_name": "Probable methyltransferase-like protein 24", "gene_name": "Mettl24", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATVKPPGRGCGALPRWLLGAALLLGLRLCMELRHAGSGPPGRGDSPGPPRTHLLSAPGSPRGARRRQVTYVRSGRRVLPRGGGSTTSPEPSCCAQGGLLRRKGSRWHIELQPWAGPSRSLDEEASRFLSYISTTQIACDHMGTDSLATDSSPAPKPWLVCLDDRFGLAHQIRSKRCRLYSLGLGSDDTHFEVSMANGGCEVHRFDPSVKSAHVLERQGLWHHRLSIDWRDPHPAVAAQKPHGNTRKLGSILNEFGHHKIDVLKADLESAEWKVLENLILEDVLEQIGQLVFEIHLHWPGFEVSGSESGVVRFWYSLLKELERKHFRLFHTYKDLTKPQLFLKKDLFNASSCYTLSWVNTKWR", "length": 363 }, "evidence": [ { "id": "HGNC:21566", "url": "https://alliancegenome.org/gene/HGNC:21566#orthology", "database": "AGR" }, { "id": "RGD:1564857", "url": "https://alliancegenome.org/gene/RGD:1564857#orthology", "database": "AGR" }, { "id": "MGI:3045338", "url": "https://alliancegenome.org/gene/MGI:3045338#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-138", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-138#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PQ65", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ65" }, { "id": "PF13383", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13383" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 241, "start_aa": "Gln", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PNP5-1", "uniprot_ac": "A0A8M9PNP5", "uniprot_id": "A0A8M9PNP5_DANRE", "mass": { "chemical_mass": 393743.0, "monoisotopic_mass": 393743.0 }, "refseq": { "ac": "XP_021323861", "name": "CUB and sushi domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323861" }, "gene_names": [ { "name": "csmd3b", "type": "recommended", "evidence": [ { "id": "A0A8M9PNP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5" } ] }, { "name": "csmd3b", "type": "synonym", "evidence": [ { "id": "XP_021323861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323861" } ] } ], "protein_names": [ { "name": "CUB and sushi domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323861" }, { "id": "A0A8M9PNP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323861" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNP5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "csmd3b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120214-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120214-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "572419", "url": "https://www.ncbi.nlm.nih.gov/gene/572419", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:572419", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:572419", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z2H7", "url": "https://www.orthodb.org/?gene=A0A8M6Z2H7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PNP5", "url": "https://www.orthodb.org/?gene=A0A8M9PNP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323861", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323861", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2H7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2H7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PNP5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PNP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TEY4", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEY4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TEY4-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEY4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I188", "url": "https://www.uniprot.org/uniprotkb/A0AC58I188", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I188-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I188-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I190", "url": "https://www.uniprot.org/uniprotkb/A0AC58I190", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I190-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I190-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I194", "url": "https://www.uniprot.org/uniprotkb/A0AC58I194", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I194-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I194-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I1A2", "url": "https://www.uniprot.org/uniprotkb/A0AC58I1A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I1A2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I1A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120214-1", "url": "https://zfin.org/ZDB-GENE-120214-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MHIDDTEGHSVRSTGFLAVFKRGCIRCGPVDSQAKKMGIKTGVTFWNLIFFMMVTCVRGFIYTCGGTLKGRNGTIESPGFPYGYQNGANCTWVIVAEEGNRIQIVFQSFAVEEDYDFLSLYDGHPHPANFRTRLTGFQIPPPVTSTGSVFSLRLTSDFAVSAHGFKIYYEELQSSSCGNPGVPPKGILYGTRFNVGDKIRYSCVTGYVLDGHPQLTCVTNAGNAAVWDFPVPICRAEDTCGDTLRGSSGIITSPNFPSEYYNSADCTWTILADPGDTISIIFTDFQTEEKYDYLEVEGSEPPTIWLSGMNVPSPIVSNKNWLRLHFVTDSNHRYKGFSAHYQVKRSVDFKSRGVKLFPGKDNSNKFSILNEGGIKQASNSCPDPGEPENGKRIGNDFSIGATAEFTCDEDHVLQGSKSITCQRVAEVFAAWTDHRPVCRVKTCGSNLQGPSGTFSSPNFPIQYESNSQCVWIITASNLNKVIQINFEDFDLELGYDTLTIGDGGEVGDPKTILQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGTPLYGMREGDGFSNGDMLRFECQFGFELIGEKTISCQNNNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCVWLILSEPGSRIHLAFNDFDLEAPYDILTVKDGEMLDSSVLGRFTGAEVPSHLTSNSNILRLEFQADHSMSGRGFNITYTTFGHNECPDPGIPLNARRFGDSFQLGSSISIICEDGFIKTQGAETITCELNGGKVMWSGPIPKCEAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGRSIKITFEKFQTELNCDFLELHDGPNLLSPLIGSFNGTQVPQFLFSSGNHLYMLFTTDNSRSNSGFKILYESVTVDAYSCLDPGIPVNGLRYGQDFSIGSTVSFGCDSGYRLSHEEPLVCEKNHWWSHPLPTCDALCGGDVRGPGGTILSPGYPEVYPSSLNCTWTVEVSHGKGVQFTFNTFHLEDHHDYLLITENGSFVQPLARLTGAELPLPINAGLYGNFKAQLRFISDFSISYEGFNITFSEYNLEPCEDPGVPHYGRRNGYSFGIGDTLTFSCNLGYRLEGAPEIICLGGGRRMWSAPLPRCVAECGSSVINNEGILLSPNYPMNYENNHECIYSIQVQAGKGINISARTFHLAQGDILKIYDGKDNAAHMLGAFTGSSMLGLTLISTSNHLWLEFYSDAEATGEGFKLVYSSFELSHCEDPGVPQFGFKVNDQGHFSGSTITYKCDPGYTLHGSGVLKCMTGERRAWDNALPSCIAECGGRFKGETSGRILSPGYPFPYDNNLRCTWMVEVDSGNIISLQFLAFDTEASHDILRVWDGPPENEMSLREVSGSLLPENVHSTLNMVSIQFETDFYISKSGFAIEFSSSVATACRDPGVPMNGSRNGDGREPGDTVTFQCDPGYELQGDVKITCIQVENRYYWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSKDCDWLIAVNSDYVLSLAFISFSIEPNYDFLYIYDGADSNSPLIGSFQDSKLPERIESSSNTMYLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNVMNGTRLGSDYKLGSTVTFYCEAGYVLQGYSTLTCIMGDDGRPGWNRGLPSCQAPCGSRSTGTDGTVLSPNFPRNYTTGQSCVYTIAVPREFVLFGQFVLFQTSLNDVVDIYDGPTQQSSLLSSLSGSHSGESLPLSTGNQITIKFSTVGPETAKGFHFVYQAVPRTSATQCSSVPEPRFGKRIGNNFAVGASVMFECNPGYTLHGSTAIHCETVPDALAQWNDTLPTCIVPCGGILTMRKGTILSPGYPEPYDNNLNCVWKVSVPEGAGIQIQVVSFATEHNWDSLDFYDGADNNAPRLGSYSGTTIPQLLNSTSNNLYLNFVSDISVSAAGFHLEYTAIGLDTCPEPQTPTYGIKIGDRYMVGDVVMFQCEQGYSLQGNAHITCMPGPVRRWNYPVPLCLAQCGGAMTEVSGVILSPGFPGNYPSGLDCTWTITLPIGFGIHVQFLNFSTEAIHDYLEIRSGPSETGTVIDRFSGPQVPESLFSTTHETSFFFHSDYSQNKPGFHITYQAYQLQSCPDPRPFRNGIVIGSDFSVGMTVSFECLPGYSLIGETSLTCLHGISRNWNNPIPRCEALCGGNITSMNGTIFSPGHPAEYPNFQDCVWSVRVPPGNGIYINFTVLSTEPIYDYITVWDGPDQSSPQIGQFSGNTALESVYSTSNQILIKFHSDFSGSGFFVLSYHAYQLRVCQPPLEVANADILMEDNELEIGDIIRYRCHPGFTLVGSEILTCRLGERLQMDGHPPSCQVQCPAHDVRFDSSGVILSPGYPDSYPNLQMCSWSINVEKGYNITLFFEFFQTEKEYDILEVFDGPTIHSQTLATLSGDLPTPFNMTTSGHQLLLRWSADHGTNKKGFSIRYVGEYQTLYCSTPDSPLHGSISSQTGGHLNSLVRWTCDRGYRLIGKSTAVCKKTPFGFYDWDAPVPACQAVSCGVPKAPVNGGVLAMDYSVGTRVTYFCSDGYRLSSKELTSAVCQPDGTWSNHNKVPRCSVVVCPSIGSFSLEHGRWRIVNGSHYEYRTKIIFTCDPGYYRLGPAYIQCMANGAWSWKNERPHCQIISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCLAGHCGLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIGSSVRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNMGYVMEGPSRAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMDGYLLSGSTTRQCQANGTWSGTAPNCTLINCGEPGVPANGLRYGEDFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVTCTAPPPISNGLLEGRDFEWGTSVSYSCSPGYELSFPAILTCVGNGTWSGEVPQCLPKFCGDPGTPAFGSREGRSFIYQSEVSFSCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPRYGSLNRTFGFKVGSMVAFQCQPGHLLQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHVDVVGMDLPSYGYTLIYSCQSGFFLSGGSEHRVCRSDGTWTGKMPVCRAGSKLSEKPIKPVPGTPSPKLNVPDDVFAPNYIWKGSYNYKGRKQPMTLSITSFNTTTGRVNVTLTSSNMELLLSGVYKSQEARLMLLVYHVKASSSSTLSKIKEEHWTLDGFVSAEPDGSTYVFQGFIQGKDYGQFGLQRLGLNMSESNNSSNPPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTTPKTQYTGCSVHENNNGQAAFENPMYNTKPEVKNVRFDPNLNTVCTMV", "length": 3603, "header": "tr|A0A8M9PNP5-1|A0A8M9PNP5_DANRE Isoform 1 of CUB and sushi domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=csmd3b PE=3 SV=1 CANONICAL=A0A8M9PNP5-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z2H7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5/entry#A0A8M6Z2H7-1", "sequence": { "sequence": "MHIDDTEGHSVRSTGFLAVFKRGCIRCGPVDSQAKKMGIKTGVTFWNLIFFMMVTCVRGFIYTCGGTLKGRNGTIESPGFPYGYQNGANCTWVIVAEEGNRIQIVFQSFAVEEDYDFLSLYDGHPHPANFRTRLTGFQIPPPVTSTGSVFSLRLTSDFAVSAHGFKIYYEELQSSSCGNPGVPPKGILYGTRFNVGDKIRYSCVTGYVLDGHPQLTCVTNAGNAAVWDFPVPICRAEDTCGDTLRGSSGIITSPNFPSEYYNSADCTWTILADPGDTISIIFTDFQTEEKYDYLEVEGSEPPTIWLSGMNVPSPIVSNKNWLRLHFVTDSNHRYKGFSAHYQVKRSVDFKSRGVKLFPGKDNSNKFSILNEGGIKQASNSCPDPGEPENGKRIGNDFSIGATAEFTCDEDHVLQGSKSITCQRVAEVFAAWTDHRPVCRVKTCGSNLQGPSGTFSSPNFPIQYESNSQCVWIITASNLNKVIQINFEDFDLELGYDTLTIGDGGEVGDPKTILQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGTPLYGMREGDGFSNGDMLRFECQFGFELIGEKTISCQNNNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCVWLILSEPGSRIHLAFNDFDLEAPYDILTVKDGEMLDSSVLGRFTGAEVPSHLTSNSNILRLEFQADHSMSGRGFNITYTTFGHNECPDPGIPLNARRFGDSFQLGSSISIICEDGFIKTQGAETITCELNGGKVMWSGPIPKCEAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGRSIKITFEKFQTELNCDFLELHDGPNLLSPLIGSFNGTQVPQFLFSSGNHLYMLFTTDNSRSNSGFKILYESVTVDAYSCLDPGIPVNGLRYGQDFSIGSTVSFGCDSGYRLSHEEPLVCEKNHWWSHPLPTCDALCGGDVRGPGGTILSPGYPEVYPSSLNCTWTVEVSHGKGVQFTFNTFHLEDHHDYLLITENGSFVQPLARLTGAELPLPINAGLYGNFKAQLRFISDFSISYEGFNITFSEYNLEPCEDPGVPHYGRRNGYSFGIGDTLTFSCNLGYRLEGAPEIICLGGGRRMWSAPLPRCVAECGSSVINNEGILLSPNYPMNYENNHECIYSIQVQAGKGINISARTFHLAQGDILKIYDGKDNAAHMLGAFTGSSMLGLTLISTSNHLWLEFYSDAEATGEGFKLVYSSFELSHCEDPGVPQFGFKVNDQGHFSGSTITYKCDPGYTLHGSGVLKCMTGERRAWDNALPSCIAECGGRFKGETSGRILSPGYPFPYDNNLRCTWMVEVDSGNIISLQFLAFDTEASHDILRVWDGPPENEMSLREVSGSLLPENVHSTLNMVSIQFETDFYISKSGFAIEFSSSVATACRDPGVPMNGSRNGDGREPGDTVTFQCDPGYELQGDVKITCIQVENRYYWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSKDCDWLIAVNSDYVLSLAFISFSIEPNYDFLYIYDGADSNSPLIGSFQDSKLPERIESSSNTMYLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNVMNGTRLGSDYKLGSTVTFYCEAGYVLQGYSTLTCIMGDDGRPGWNRGLPSCQAPCGSRSTGTDGTVLSPNFPRNYTTGQSCVYTIAVPREFVLFGQFVLFQTSLNDVVDIYDGPTQQSSLLSSLSGSHSGESLPLSTGNQITIKFSTVGPETAKGFHFVYQAVPRTSATQCSSVPEPRFGKRIGNNFAVGASVMFECNPGYTLHGSTAIHCETVPDALAQWNDTLPTCIVPCGGILTMRKGTILSPGYPEPYDNNLNCVWKVSVPEGAGIQIQVVSFATEHNWDSLDFYDGADNNAPRLGSYSGTTIPQLLNSTSNNLYLNFVSDISVSAAGFHLEYTAIGLDTCPEPQTPTYGIKIGDRYMVGDVVMFQCEQGYSLQGNAHITCMPGPVRRWNYPVPLCLAQCGGAMTEVSGVILSPGFPGNYPSGLDCTWTITLPIGFGIHVQFLNFSTEAIHDYLEIRSGPSETGTVIDRFSGPQVPESLFSTTHETSFFFHSDYSQNKPGFHITYQAYQLQSCPDPRPFRNGIVIGSDFSVGMTVSFECLPGYSLIGETSLTCLHGISRNWNNPIPRCEALCGGNITSMNGTIFSPGHPAEYPNFQDCVWSVRVPPGNGIYINFTVLSTEPIYDYITVWDGPDQSSPQIGQFSGNTALESVYSTSNQILIKFHSDFSGSGFFVLSYHAYQLRVCQPPLEVANADILMEDNELEIGDIIRYRCHPGFTLVGSEILTCRLGERLQMDGHPPSCQVQCPAHDVRFDSSGVILSPGYPDSYPNLQMCSWSINVEKGYNITLFFEFFQTEKEYDILEVFDGPTIHSQTLATLSGDLPTPFNMTTSGHQLLLRWSADHGTNKKGFSIRYVALYCSTPDSPLHGSISSQTGGHLNSLVRWTCDRGYRLIGKSTAVCKKTPFGFYDWDAPVPACQAVSCGVPKAPVNGGVLAMDYSVGTRVTYFCSDGYRLSSKELTSAVCQPDGTWSNHNKVPRCSVVVCPSIGSFSLEHGRWRIVNGSHYEYRTKIIFTCDPGYYRLGPAYIQCMANGAWSWKNERPHCQIISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCLAGHCGLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIGSSVRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNMGYVMEGPSRAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMDGYLLSGSTTRQCQANGTWSGTAPNCTLINCGEPGVPANGLRYGEDFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVTCTAPPPISNGLLEGRDFEWGTSVSYSCSPGYELSFPAILTCVGNGTWSGEVPQCLPKFCGDPGTPAFGSREGRSFIYQSEVSFSCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPRYGSLNRTFGFKVGSMVAFQCQPGHLLQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHVDVVGMDLPSYGYTLIYSCQSGFFLSGGSEHRVCRSDGTWTGKMPVCRAGSKLSEKPIKPVPGTPSPKLNVPDDVFAPNYIWKGSYNYKGRKQPMTLSITSFNTTTGRVNVTLTSSNMELLLSGVYKSQEARLMLLVYHVKASSSSTLSKIKEEHWTLDGFVSAEPDGSTYVFQGFIQGKDYGQFGLQRLGLNMSESNNSSNPPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTTPKTQYTGCSVHENNNGQAAFENPMYNTKPEVKNVRFDPNLNTVCTMV", "length": 3599, "header": "tr|A0A8M6Z2H7-1|A0A8M9PNP5_DANRE Computationally mapped isoform of CUB and sushi domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=csmd3b PE=3 SV=1 CANONICAL=A0A8M9PNP5-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PNP5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5/entry#A0A8M9PNP5-1", "sequence": { "sequence": "MHIDDTEGHSVRSTGFLAVFKRGCIRCGPVDSQAKKMGIKTGVTFWNLIFFMMVTCVRGFIYTCGGTLKGRNGTIESPGFPYGYQNGANCTWVIVAEEGNRIQIVFQSFAVEEDYDFLSLYDGHPHPANFRTRLTGFQIPPPVTSTGSVFSLRLTSDFAVSAHGFKIYYEELQSSSCGNPGVPPKGILYGTRFNVGDKIRYSCVTGYVLDGHPQLTCVTNAGNAAVWDFPVPICRAEDTCGDTLRGSSGIITSPNFPSEYYNSADCTWTILADPGDTISIIFTDFQTEEKYDYLEVEGSEPPTIWLSGMNVPSPIVSNKNWLRLHFVTDSNHRYKGFSAHYQVKRSVDFKSRGVKLFPGKDNSNKFSILNEGGIKQASNSCPDPGEPENGKRIGNDFSIGATAEFTCDEDHVLQGSKSITCQRVAEVFAAWTDHRPVCRVKTCGSNLQGPSGTFSSPNFPIQYESNSQCVWIITASNLNKVIQINFEDFDLELGYDTLTIGDGGEVGDPKTILQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGTPLYGMREGDGFSNGDMLRFECQFGFELIGEKTISCQNNNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCVWLILSEPGSRIHLAFNDFDLEAPYDILTVKDGEMLDSSVLGRFTGAEVPSHLTSNSNILRLEFQADHSMSGRGFNITYTTFGHNECPDPGIPLNARRFGDSFQLGSSISIICEDGFIKTQGAETITCELNGGKVMWSGPIPKCEAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGRSIKITFEKFQTELNCDFLELHDGPNLLSPLIGSFNGTQVPQFLFSSGNHLYMLFTTDNSRSNSGFKILYESVTVDAYSCLDPGIPVNGLRYGQDFSIGSTVSFGCDSGYRLSHEEPLVCEKNHWWSHPLPTCDALCGGDVRGPGGTILSPGYPEVYPSSLNCTWTVEVSHGKGVQFTFNTFHLEDHHDYLLITENGSFVQPLARLTGAELPLPINAGLYGNFKAQLRFISDFSISYEGFNITFSEYNLEPCEDPGVPHYGRRNGYSFGIGDTLTFSCNLGYRLEGAPEIICLGGGRRMWSAPLPRCVAECGSSVINNEGILLSPNYPMNYENNHECIYSIQVQAGKGINISARTFHLAQGDILKIYDGKDNAAHMLGAFTGSSMLGLTLISTSNHLWLEFYSDAEATGEGFKLVYSSFELSHCEDPGVPQFGFKVNDQGHFSGSTITYKCDPGYTLHGSGVLKCMTGERRAWDNALPSCIAECGGRFKGETSGRILSPGYPFPYDNNLRCTWMVEVDSGNIISLQFLAFDTEASHDILRVWDGPPENEMSLREVSGSLLPENVHSTLNMVSIQFETDFYISKSGFAIEFSSSVATACRDPGVPMNGSRNGDGREPGDTVTFQCDPGYELQGDVKITCIQVENRYYWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSKDCDWLIAVNSDYVLSLAFISFSIEPNYDFLYIYDGADSNSPLIGSFQDSKLPERIESSSNTMYLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNVMNGTRLGSDYKLGSTVTFYCEAGYVLQGYSTLTCIMGDDGRPGWNRGLPSCQAPCGSRSTGTDGTVLSPNFPRNYTTGQSCVYTIAVPREFVLFGQFVLFQTSLNDVVDIYDGPTQQSSLLSSLSGSHSGESLPLSTGNQITIKFSTVGPETAKGFHFVYQAVPRTSATQCSSVPEPRFGKRIGNNFAVGASVMFECNPGYTLHGSTAIHCETVPDALAQWNDTLPTCIVPCGGILTMRKGTILSPGYPEPYDNNLNCVWKVSVPEGAGIQIQVVSFATEHNWDSLDFYDGADNNAPRLGSYSGTTIPQLLNSTSNNLYLNFVSDISVSAAGFHLEYTAIGLDTCPEPQTPTYGIKIGDRYMVGDVVMFQCEQGYSLQGNAHITCMPGPVRRWNYPVPLCLAQCGGAMTEVSGVILSPGFPGNYPSGLDCTWTITLPIGFGIHVQFLNFSTEAIHDYLEIRSGPSETGTVIDRFSGPQVPESLFSTTHETSFFFHSDYSQNKPGFHITYQAYQLQSCPDPRPFRNGIVIGSDFSVGMTVSFECLPGYSLIGETSLTCLHGISRNWNNPIPRCEALCGGNITSMNGTIFSPGHPAEYPNFQDCVWSVRVPPGNGIYINFTVLSTEPIYDYITVWDGPDQSSPQIGQFSGNTALESVYSTSNQILIKFHSDFSGSGFFVLSYHAYQLRVCQPPLEVANADILMEDNELEIGDIIRYRCHPGFTLVGSEILTCRLGERLQMDGHPPSCQVQCPAHDVRFDSSGVILSPGYPDSYPNLQMCSWSINVEKGYNITLFFEFFQTEKEYDILEVFDGPTIHSQTLATLSGDLPTPFNMTTSGHQLLLRWSADHGTNKKGFSIRYVGEYQTLYCSTPDSPLHGSISSQTGGHLNSLVRWTCDRGYRLIGKSTAVCKKTPFGFYDWDAPVPACQAVSCGVPKAPVNGGVLAMDYSVGTRVTYFCSDGYRLSSKELTSAVCQPDGTWSNHNKVPRCSVVVCPSIGSFSLEHGRWRIVNGSHYEYRTKIIFTCDPGYYRLGPAYIQCMANGAWSWKNERPHCQIISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCLAGHCGLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIGSSVRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNMGYVMEGPSRAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMDGYLLSGSTTRQCQANGTWSGTAPNCTLINCGEPGVPANGLRYGEDFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVTCTAPPPISNGLLEGRDFEWGTSVSYSCSPGYELSFPAILTCVGNGTWSGEVPQCLPKFCGDPGTPAFGSREGRSFIYQSEVSFSCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPRYGSLNRTFGFKVGSMVAFQCQPGHLLQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHVDVVGMDLPSYGYTLIYSCQSGFFLSGGSEHRVCRSDGTWTGKMPVCRAGSKLSEKPIKPVPGTPSPKLNVPDDVFAPNYIWKGSYNYKGRKQPMTLSITSFNTTTGRVNVTLTSSNMELLLSGVYKSQEARLMLLVYHVKASSSSTLSKIKEEHWTLDGFVSAEPDGSTYVFQGFIQGKDYGQFGLQRLGLNMSESNNSSNPPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTTPKTQYTGCSVHENNNGQAAFENPMYNTKPEVKNVRFDPNLNTVCTMV", "length": 3603, "header": "tr|A0A8M9PNP5-1|A0A8M9PNP5_DANRE Isoform 1 of CUB and sushi domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=csmd3b PE=3 SV=1 CANONICAL=A0A8M9PNP5-1" }, "locus": {} }, { "isoform_ac": "A0AB32TEY4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5/entry#A0AB32TEY4-1", "sequence": { "sequence": "MHIDDTEGHSVRSTGFLAVFKRGCIRCGPVDSQAKKMGIKTGVTFWNLIFFMMVTCVRGFIYTCGGTLKGRNGTIESPGFPYGYQNGANCTWVIVAEEGNRIQIVFQSFAVEEDYDFLSLYDGHPHPANFRTRLTGFQIPPPVTSTGSVFSLRLTSDFAVSAHGFKIYYEELQSSSCGNPGVPPKGILYGTRFNVGDKIRYSCVTGYVLDGHPQLTCVTNAGNAAVWDFPVPICRAEDTCGDTLRGSSGIITSPNFPSEYYNSADCTWTILADPGDTISIIFTDFQTEEKYDYLEVEGSEPPTIWLSGMNVPSPIVSNKNWLRLHFVTDSNHRYKGFSAHYQVNEGGIKQASNSCPDPGEPENGKRIGNDFSIGATAEFTCDEDHVLQGSKSITCQRVAEVFAAWTDHRPVCRVKTCGSNLQGPSGTFSSPNFPIQYESNSQCVWIITASNLNKVIQINFEDFDLELGYDTLTIGDGGEVGDPKTILQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGTPLYGMREGDGFSNGDMLRFECQFGFELIGEKTISCQNNNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCVWLILSEPGSRIHLAFNDFDLEAPYDILTVKDGEMLDSSVLGRFTGAEVPSHLTSNSNILRLEFQADHSMSGRGFNITYTTFGHNECPDPGIPLNARRFGDSFQLGSSISIICEDGFIKTQGAETITCELNGGKVMWSGPIPKCEAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGRSIKITFEKFQTELNCDFLELHDGPNLLSPLIGSFNGTQVPQFLFSSGNHLYMLFTTDNSRSNSGFKILYESVTVDAYSCLDPGIPVNGLRYGQDFSIGSTVSFGCDSGYRLSHEEPLVCEKNHWWSHPLPTCDALCGGDVRGPGGTILSPGYPEVYPSSLNCTWTVEVSHGKGVQFTFNTFHLEDHHDYLLITENGSFVQPLARLTGAELPLPINAGLYGNFKAQLRFISDFSISYEGFNITFSEYNLEPCEDPGVPHYGRRNGYSFGIGDTLTFSCNLGYRLEGAPEIICLGGGRRMWSAPLPRCVAECGSSVINNEGILLSPNYPMNYENNHECIYSIQVQAGKGINISARTFHLAQGDILKIYDGKDNAAHMLGAFTGSSMLGLTLISTSNHLWLEFYSDAEATGEGFKLVYSSFELSHCEDPGVPQFGFKVNDQGHFSGSTITYKCDPGYTLHGSGVLKCMTGERRAWDNALPSCIAECGGRFKGETSGRILSPGYPFPYDNNLRCTWMVEVDSGNIISLQFLAFDTEASHDILRVWDGPPENEMSLREVSGSLLPENVHSTLNMVSIQFETDFYISKSGFAIEFSSSVATACRDPGVPMNGSRNGDGREPGDTVTFQCDPGYELQGDVKITCIQVENRYYWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSKDCDWLIAVNSDYVLSLAFISFSIEPNYDFLYIYDGADSNSPLIGSFQDSKLPERIESSSNTMYLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNVMNGTRLGSDYKLGSTVTFYCEAGYVLQGYSTLTCIMGDDGRPGWNRGLPSCQAPCGSRSTGTDGTVLSPNFPRNYTTGQSCVYTIAVPREFVLFGQFVLFQTSLNDVVDIYDGPTQQSSLLSSLSGSHSGESLPLSTGNQITIKFSTVGPETAKGFHFVYQAVPRTSATQCSSVPEPRFGKRIGNNFAVGASVMFECNPGYTLHGSTAIHCETVPDALAQWNDTLPTCIVPCGGILTMRKGTILSPGYPEPYDNNLNCVWKVSVPEGAGIQIQVVSFATEHNWDSLDFYDGADNNAPRLGSYSGTTIPQLLNSTSNNLYLNFVSDISVSAAGFHLEYTAIGLDTCPEPQTPTYGIKIGDRYMVGDVVMFQCEQGYSLQGNAHITCMPGPVRRWNYPVPLCLAQCGGAMTEVSGVILSPGFPGNYPSGLDCTWTITLPIGFGIHVQFLNFSTEAIHDYLEIRSGPSETGTVIDRFSGPQVPESLFSTTHETSFFFHSDYSQNKPGFHITYQAYQLQSCPDPRPFRNGIVIGSDFSVGMTVSFECLPGYSLIGETSLTCLHGISRNWNNPIPRCEALCGGNITSMNGTIFSPGHPAEYPNFQDCVWSVRVPPGNGIYINFTVLSTEPIYDYITVWDGPDQSSPQIGQFSGNTALESVYSTSNQILIKFHSDFSGSGFFVLSYHAYQLRVCQPPLEVANADILMEDNELEIGDIIRYRCHPGFTLVGSEILTCRLGERLQMDGHPPSCQVQCPAHDVRFDSSGVILSPGYPDSYPNLQMCSWSINVEKGYNITLFFEFFQTEKEYDILEVFDGPTIHSQTLATLSGDLPTPFNMTTSGHQLLLRWSADHGTNKKGFSIRYVALYCSTPDSPLHGSISSQTGGHLNSLVRWTCDRGYRLIGKSTAVCKKTPFGFYDWDAPVPACQAVSCGVPKAPVNGGVLAMDYSVGTRVTYFCSDGYRLSSKELTSAVCQPDGTWSNHNKVPRCSVVVCPSIGSFSLEHGRWRIVNGSHYEYRTKIIFTCDPGYYRLGPAYIQCMANGAWSWKNERPHCQIISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCLAGHCGLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIGSSVRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNMGYVMEGPSRAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMDGYLLSGSTTRQCQANGTWSGTAPNCTLINCGEPGVPANGLRYGEDFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVTCTAPPPISNGLLEGRDFEWGTSVSYSCSPGYELSFPAILTCVGNGTWSGEVPQCLPKFCGDPGTPAFGSREGRSFIYQSEVSFSCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPRYGSLNRTFGFKVGSMVAFQCQPGHLLQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHVDVVGMDLPSYGYTLIYSCQSGFFLSGGSEHRVCRSDGTWTGKMPVCRAGSKLSEKPIKPVPGTPSPKLNVPDDVFAPNYIWKGSYNYKGRKQPMTLSITSFNTTTGRVNVTLTSSNMELLLSGVYKSQEARLMLLVYHVKASSSSTLSKIKEEHWTLDGFVSAEPDGSTYVFQGFIQGKDYGQFGLQRLGLNMSESNNSSNPPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTTPKTQYTGCSVHENNNGQAAFENPMYNTKPEVKNVRFDPNLNTVCTMV", "length": 3573, "header": "tr|A0AB32TEY4-1|A0A8M9PNP5_DANRE Computationally mapped isoform of CUB and sushi domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=csmd3b PE=3 SV=1 CANONICAL=A0A8M9PNP5-1" }, "locus": {} }, { "isoform_ac": "A0AC58I188-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5/entry#A0AC58I188-1", "sequence": { "sequence": "MNVPSPIVSNKNWLRLHFVTDSNHRYKGFSAHYQVNEGGIKQASNSCPDPGEPENGKRIGNDFSIGATAEFTCDEDHVLQGSKSITCQRVAEVFAAWTDHRPVCRVKTCGSNLQGPSGTFSSPNFPIQYESNSQCVWIITASNLNKVIQINFEDFDLELGYDTLTIGDGGEVGDPKTILQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGTPLYGMREGDGFSNGDMLRFECQFGFELIGEKTISCQNNNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCVWLILSEPGSRIHLAFNDFDLEAPYDILTVKDGEMLDSSVLGRFTGAEVPSHLTSNSNILRLEFQADHSMSGRGFNITYTTFGHNECPDPGIPLNARRFGDSFQLGSSISIICEDGFIKTQGAETITCELNGGKVMWSGPIPKCEAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGRSIKITFEKFQTELNCDFLELHDGPNLLSPLIGSFNGTQVPQFLFSSGNHLYMLFTTDNSRSNSGFKILYESVTVDAYSCLDPGIPVNGLRYGQDFSIGSTVSFGCDSGYRLSHEEPLVCEKNHWWSHPLPTCDALCGGDVRGPGGTILSPGYPEVYPSSLNCTWTVEVSHGKGVQFTFNTFHLEDHHDYLLITENGSFVQPLARLTGAELPLPINAGLYGNFKAQLRFISDFSISYEGFNITFSEYNLEPCEDPGVPHYGRRNGYSFGIGDTLTFSCNLGYRLEGAPEIICLGGGRRMWSAPLPRCVAECGSSVINNEGILLSPNYPMNYENNHECIYSIQVQAGKGINISARTFHLAQGDILKIYDGKDNAAHMLGAFTGSSMLGLTLISTSNHLWLEFYSDAEATGEGFKLVYSSFELSHCEDPGVPQFGFKVNDQGHFSGSTITYKCDPGYTLHGSGVLKCMTGERRAWDNALPSCIAECGGRFKGETSGRILSPGYPFPYDNNLRCTWMVEVDSGNIISLQFLAFDTEASHDILRVWDGPPENEMSLREVSGSLLPENVHSTLNMVSIQFETDFYISKSGFAIEFSSSVATACRDPGVPMNGSRNGDGREPGDTVTFQCDPGYELQGDVKITCIQVENRYYWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSKDCDWLIAVNSDYVLSLAFISFSIEPNYDFLYIYDGADSNSPLIGSFQDSKLPERIESSSNTMYLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNVMNGTRLGSDYKLGSTVTFYCEAGYVLQGYSTLTCIMGDDGRPGWNRGLPSCQAPCGSRSTGTDGTVLSPNFPRNYTTGQSCVYTIAVPREFVLFGQFVLFQTSLNDVVDIYDGPTQQSSLLSSLSGSHSGESLPLSTGNQITIKFSTVGPETAKGFHFVYQAVPRTSATQCSSVPEPRFGKRIGNNFAVGASVMFECNPGYTLHGSTAIHCETVPDALAQWNDTLPTCIVPCGGILTMRKGTILSPGYPEPYDNNLNCVWKVSVPEGAGIQIQVVSFATEHNWDSLDFYDGADNNAPRLGSYSGTTIPQLLNSTSNNLYLNFVSDISVSAAGFHLEYTAIGLDTCPEPQTPTYGIKIGDRYMVGDVVMFQCEQGYSLQGNAHITCMPGPVRRWNYPVPLCLAQCGGAMTEVSGVILSPGFPGNYPSGLDCTWTITLPIGFGIHVQFLNFSTEAIHDYLEIRSGPSETGTVIDRFSGPQVPESLFSTTHETSFFFHSDYSQNKPGFHITYQAYQLQSCPDPRPFRNGIVIGSDFSVGMTVSFECLPGYSLIGETSLTCLHGISRNWNNPIPRCEALCGGNITSMNGTIFSPGHPAEYPNFQDCVWSVRVPPGNGIYINFTVLSTEPIYDYITVWDGPDQSSPQIGQFSGNTALESVYSTSNQILIKFHSDFSGSGFFVLSYHAYQLRVCQPPLEVANADILMEDNELEIGDIIRYRCHPGFTLVGSEILTCRLGERLQMDGHPPSCQVQCPAHDVRFDSSGVILSPGYPDSYPNLQMCSWSINVEKGYNITLFFEFFQTEKEYDILEVFDGPTIHSQTLATLSGDLPTPFNMTTSGHQLLLRWSADHGTNKKGFSIRYVALYCSTPDSPLHGSISSQTGGHLNSLVRWTCDRGYRLIGKSTAVCKKTPFGFYDWDAPVPACQAVSCGVPKAPVNGGVLAMDYSVGTRVTYFCSDGYRLSSKELTSAVCQPDGTWSNHNKVPRCSVVVCPSIGSFSLEHGRWRIVNGSHYEYRTKIIFTCDPGYYRLGPAYIQCMANGAWSWKNERPHCQIISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCLAGHCGLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIGSSVRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNMGYVMEGPSRAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMDGYLLSGSTTRQCQANGTWSGTAPNCTLINCGEPGVPANGLRYGEDFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVTCTAPPPISNGLLEGRDFEWGTSVSYSCSPGYELSFPAILTCVGNGTWSGEVPQCLPKFCGDPGTPAFGSREGRSFIYQSEVSFSCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPRYGSLNRTFGFKVGSMVAFQCQPGHLLQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHVDVVGMDLPSYGYTLIYSCQSGFFLSGGSEHRVCRSDGTWTGKMPVCRAGSKLSEKPIKPVPGTPSPKLNVPDDVFAPNYIWKGSYNYKGRKQPMTLSITSFNTTTGRVNVTLTSSNMELLLSGVYKSQEARLMLLVYHVKASSSSTLSKIKEEHWTLDGFVSAEPDGSTYVFQGFIQGKDYGQFGLQRLGLNMSESNNSSNPPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTTPKTQYTGCSVHENNNGQAAFENPMYNTKPEVKNVRFDPNLNTVCTMV", "length": 3265, "header": "tr|A0AC58I188-1|A0AC58I188_DANRE Computationally mapped isoform of CUB and sushi domain-containing protein 3 isoform X6 OS=Danio rerio OX=7955 GN=csmd3b PE=3 SV=1 CANONICAL=A0A8M9PNP5-1" }, "locus": {} }, { "isoform_ac": "A0AC58I190-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5/entry#A0AC58I190-1", "sequence": { "sequence": "MNVPSPIVSNKNWLRLHFVTDSNHRYKGFSAHYQVKRSVDFKSRGVKLFPGKDNSNKFSILNEGGIKQASNSCPDPGEPENGKRIGNDFSIGATAEFTCDEDHVLQGSKSITCQRVAEVFAAWTDHRPVCRVKTCGSNLQGPSGTFSSPNFPIQYESNSQCVWIITASNLNKVIQINFEDFDLELGYDTLTIGDGGEVGDPKTILQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGTPLYGMREGDGFSNGDMLRFECQFGFELIGEKTISCQNNNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCVWLILSEPGSRIHLAFNDFDLEAPYDILTVKDGEMLDSSVLGRFTGAEVPSHLTSNSNILRLEFQADHSMSGRGFNITYTTFGHNECPDPGIPLNARRFGDSFQLGSSISIICEDGFIKTQGAETITCELNGGKVMWSGPIPKCEAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGRSIKITFEKFQTELNCDFLELHDGPNLLSPLIGSFNGTQVPQFLFSSGNHLYMLFTTDNSRSNSGFKILYESVTVDAYSCLDPGIPVNGLRYGQDFSIGSTVSFGCDSGYRLSHEEPLVCEKNHWWSHPLPTCDALCGGDVRGPGGTILSPGYPEVYPSSLNCTWTVEVSHGKGVQFTFNTFHLEDHHDYLLITENGSFVQPLARLTGAELPLPINAGLYGNFKAQLRFISDFSISYEGFNITFSEYNLEPCEDPGVPHYGRRNGYSFGIGDTLTFSCNLGYRLEGAPEIICLGGGRRMWSAPLPRCVAECGSSVINNEGILLSPNYPMNYENNHECIYSIQVQAGKGINISARTFHLAQGDILKIYDGKDNAAHMLGAFTGSSMLGLTLISTSNHLWLEFYSDAEATGEGFKLVYSSFELSHCEDPGVPQFGFKVNDQGHFSGSTITYKCDPGYTLHGSGVLKCMTGERRAWDNALPSCIAECGGRFKGETSGRILSPGYPFPYDNNLRCTWMVEVDSGNIISLQFLAFDTEASHDILRVWDGPPENEMSLREVSGSLLPENVHSTLNMVSIQFETDFYISKSGFAIEFSSSVATACRDPGVPMNGSRNGDGREPGDTVTFQCDPGYELQGDVKITCIQVENRYYWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSKDCDWLIAVNSDYVLSLAFISFSIEPNYDFLYIYDGADSNSPLIGSFQDSKLPERIESSSNTMYLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNVMNGTRLGSDYKLGSTVTFYCEAGYVLQGYSTLTCIMGDDGRPGWNRGLPSCQAPCGSRSTGTDGTVLSPNFPRNYTTGQSCVYTIAVPREFVLFGQFVLFQTSLNDVVDIYDGPTQQSSLLSSLSGSHSGESLPLSTGNQITIKFSTVGPETAKGFHFVYQAVPRTSATQCSSVPEPRFGKRIGNNFAVGASVMFECNPGYTLHGSTAIHCETVPDALAQWNDTLPTCIVPCGGILTMRKGTILSPGYPEPYDNNLNCVWKVSVPEGAGIQIQVVSFATEHNWDSLDFYDGADNNAPRLGSYSGTTIPQLLNSTSNNLYLNFVSDISVSAAGFHLEYTAIGLDTCPEPQTPTYGIKIGDRYMVGDVVMFQCEQGYSLQGNAHITCMPGPVRRWNYPVPLCLAQCGGAMTEVSGVILSPGFPGNYPSGLDCTWTITLPIGFGIHVQFLNFSTEAIHDYLEIRSGPSETGTVIDRFSGPQVPESLFSTTHETSFFFHSDYSQNKPGFHITYQAYQLQSCPDPRPFRNGIVIGSDFSVGMTVSFECLPGYSLIGETSLTCLHGISRNWNNPIPRCEALCGGNITSMNGTIFSPGHPAEYPNFQDCVWSVRVPPGNGIYINFTVLSTEPIYDYITVWDGPDQSSPQIGQFSGNTALESVYSTSNQILIKFHSDFSGSGFFVLSYHAYQLRVCQPPLEVANADILMEDNELEIGDIIRYRCHPGFTLVGSEILTCRLGERLQMDGHPPSCQVQCPAHDVRFDSSGVILSPGYPDSYPNLQMCSWSINVEKGYNITLFFEFFQTEKEYDILEVFDGPTIHSQTLATLSGDLPTPFNMTTSGHQLLLRWSADHGTNKKGFSIRYVGEYQTLYCSTPDSPLHGSISSQTGGHLNSLVRWTCDRGYRLIGKSTAVCKKTPFGFYDWDAPVPACQAVSCGVPKAPVNGGVLAMDYSVGTRVTYFCSDGYRLSSKELTSAVCQPDGTWSNHNKVPRCSVVVCPSIGSFSLEHGRWRIVNGSHYEYRTKIIFTCDPGYYRLGPAYIQCMANGAWSWKNERPHCQIISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCLAGHCGLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIGSSVRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNMGYVMEGPSRAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMDGYLLSGSTTRQCQANGTWSGTAPNCTLINCGEPGVPANGLRYGEDFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVTCTAPPPISNGLLEGRDFEWGTSVSYSCSPGYELSFPAILTCVGNGTWSGEVPQCLPKFCGDPGTPAFGSREGRSFIYQSEVSFSCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPRYGSLNRTFGFKVGSMVAFQCQPGHLLQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHVDVVGMDLPSYGYTLIYSCQSGFFLSGGSEHRVCRSDGTWTGKMPVCRAGSKLSEKPIKPVPGTPSPKLNVPDDVFAPNYIWKGSYNYKGRKQPMTLSITSFNTTTGRVNVTLTSSNMELLLSGVYKSQEARLMLLVYHVKASSSSTLSKIKEEHWTLDGFVSAEPDGSTYVFQGFIQGKDYGQFGLQRLGLNMSESNNSSNPPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTTPKTQYTGCSVHENNNGQAAFENPMYNTKPEVKNVRFDPNLNTVCTMV", "length": 3295, "header": "tr|A0AC58I190-1|A0AC58I190_DANRE Computationally mapped isoform of CUB and sushi domain-containing protein 3 isoform X3 OS=Danio rerio OX=7955 GN=csmd3b PE=3 SV=1 CANONICAL=A0A8M9PNP5-1" }, "locus": {} }, { "isoform_ac": "A0AC58I194-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5/entry#A0AC58I194-1", "sequence": { "sequence": "MNVPSPIVSNKNWLRLHFVTDSNHRYKGFSAHYQVKRSVDFKSRGVKLFPGKDNSNKFSILNEGGIKQASNSCPDPGEPENGKRIGNDFSIGATAEFTCDEDHVLQGSKSITCQRVAEVFAAWTDHRPVCRVKTCGSNLQGPSGTFSSPNFPIQYESNSQCVWIITASNLNKVIQINFEDFDLELGYDTLTIGDGGEVGDPKTILQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGTPLYGMREGDGFSNGDMLRFECQFGFELIGEKTISCQNNNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCVWLILSEPGSRIHLAFNDFDLEAPYDILTVKDGEMLDSSVLGRFTGAEVPSHLTSNSNILRLEFQADHSMSGRGFNITYTTFGHNECPDPGIPLNARRFGDSFQLGSSISIICEDGFIKTQGAETITCELNGGKVMWSGPIPKCEAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGRSIKITFEKFQTELNCDFLELHDGPNLLSPLIGSFNGTQVPQFLFSSGNHLYMLFTTDNSRSNSGFKILYESVTVDAYSCLDPGIPVNGLRYGQDFSIGSTVSFGCDSGYRLSHEEPLVCEKNHWWSHPLPTCDALCGGDVRGPGGTILSPGYPEVYPSSLNCTWTVEVSHGKGVQFTFNTFHLEDHHDYLLITENGSFVQPLARLTGAELPLPINAGLYGNFKAQLRFISDFSISYEGFNITFSEYNLEPCEDPGVPHYGRRNGYSFGIGDTLTFSCNLGYRLEGAPEIICLGGGRRMWSAPLPRCVAECGSSVINNEGILLSPNYPMNYENNHECIYSIQVQAGKGINISARTFHLAQGDILKIYDGKDNAAHMLGAFTGSSMLGLTLISTSNHLWLEFYSDAEATGEGFKLVYSSFELSHCEDPGVPQFGFKVNDQGHFSGSTITYKCDPGYTLHGSGVLKCMTGERRAWDNALPSCIAECGGRFKGETSGRILSPGYPFPYDNNLRCTWMVEVDSGNIISLQFLAFDTEASHDILRVWDGPPENEMSLREVSGSLLPENVHSTLNMVSIQFETDFYISKSGFAIEFSSSVATACRDPGVPMNGSRNGDGREPGDTVTFQCDPGYELQGDVKITCIQVENRYYWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSKDCDWLIAVNSDYVLSLAFISFSIEPNYDFLYIYDGADSNSPLIGSFQDSKLPERIESSSNTMYLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNVMNGTRLGSDYKLGSTVTFYCEAGYVLQGYSTLTCIMGDDGRPGWNRGLPSCQAPCGSRSTGTDGTVLSPNFPRNYTTGQSCVYTIAVPREFVLFGQFVLFQTSLNDVVDIYDGPTQQSSLLSSLSGSHSGESLPLSTGNQITIKFSTVGPETAKGFHFVYQAVPRTSATQCSSVPEPRFGKRIGNNFAVGASVMFECNPGYTLHGSTAIHCETVPDALAQWNDTLPTCIVPCGGILTMRKGTILSPGYPEPYDNNLNCVWKVSVPEGAGIQIQVVSFATEHNWDSLDFYDGADNNAPRLGSYSGTTIPQLLNSTSNNLYLNFVSDISVSAAGFHLEYTAIGLDTCPEPQTPTYGIKIGDRYMVGDVVMFQCEQGYSLQGNAHITCMPGPVRRWNYPVPLCLAQCGGAMTEVSGVILSPGFPGNYPSGLDCTWTITLPIGFGIHVQFLNFSTEAIHDYLEIRSGPSETGTVIDRFSGPQVPESLFSTTHETSFFFHSDYSQNKPGFHITYQAYQLQSCPDPRPFRNGIVIGSDFSVGMTVSFECLPGYSLIGETSLTCLHGISRNWNNPIPRCEALCGGNITSMNGTIFSPGHPAEYPNFQDCVWSVRVPPGNGIYINFTVLSTEPIYDYITVWDGPDQSSPQIGQFSGNTALESVYSTSNQILIKFHSDFSGSGFFVLSYHAYQLRVCQPPLEVANADILMEDNELEIGDIIRYRCHPGFTLVGSEILTCRLGERLQMDGHPPSCQVQCPAHDVRFDSSGVILSPGYPDSYPNLQMCSWSINVEKGYNITLFFEFFQTEKEYDILEVFDGPTIHSQTLATLSGDLPTPFNMTTSGHQLLLRWSADHGTNKKGFSIRYVALYCSTPDSPLHGSISSQTGGHLNSLVRWTCDRGYRLIGKSTAVCKKTPFGFYDWDAPVPACQAVSCGVPKAPVNGGVLAMDYSVGTRVTYFCSDGYRLSSKELTSAVCQPDGTWSNHNKVPRCSVVVCPSIGSFSLEHGRWRIVNGSHYEYRTKIIFTCDPGYYRLGPAYIQCMANGAWSWKNERPHCQIISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCLAGHCGLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIGSSVRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNMGYVMEGPSRAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMDGYLLSGSTTRQCQANGTWSGTAPNCTLINCGEPGVPANGLRYGEDFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVTCTAPPPISNGLLEGRDFEWGTSVSYSCSPGYELSFPAILTCVGNGTWSGEVPQCLPKFCGDPGTPAFGSREGRSFIYQSEVSFSCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPRYGSLNRTFGFKVGSMVAFQCQPGHLLQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHVDVVGMDLPSYGYTLIYSCQSGFFLSGGSEHRVCRSDGTWTGKMPVCRAGSKLSEKPIKPVPGTPSPKLNVPDDVFAPNYIWKGSYNYKGRKQPMTLSITSFNTTTGRVNVTLTSSNMELLLSGVYKSQEARLMLLVYHVKASSSSTLSKIKEEHWTLDGFVSAEPDGSTYVFQGFIQGKDYGQFGLQRLGLNMSESNNSSNPPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTTPKTQYTGCSVHENNNGQAAFENPMYNTKPEVKNVRFDPNLNTVCTMV", "length": 3291, "header": "tr|A0AC58I194-1|A0AC58I194_DANRE Computationally mapped isoform of CUB and sushi domain-containing protein 3 isoform X4 OS=Danio rerio OX=7955 GN=csmd3b PE=3 SV=1 CANONICAL=A0A8M9PNP5-1" }, "locus": {} }, { "isoform_ac": "A0AC58I1A2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5/entry#A0AC58I1A2-1", "sequence": { "sequence": "MNVPSPIVSNKNWLRLHFVTDSNHRYKGFSAHYQVNEGGIKQASNSCPDPGEPENGKRIGNDFSIGATAEFTCDEDHVLQGSKSITCQRVAEVFAAWTDHRPVCRVKTCGSNLQGPSGTFSSPNFPIQYESNSQCVWIITASNLNKVIQINFEDFDLELGYDTLTIGDGGEVGDPKTILQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGTPLYGMREGDGFSNGDMLRFECQFGFELIGEKTISCQNNNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCVWLILSEPGSRIHLAFNDFDLEAPYDILTVKDGEMLDSSVLGRFTGAEVPSHLTSNSNILRLEFQADHSMSGRGFNITYTTFGHNECPDPGIPLNARRFGDSFQLGSSISIICEDGFIKTQGAETITCELNGGKVMWSGPIPKCEAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGRSIKITFEKFQTELNCDFLELHDGPNLLSPLIGSFNGTQVPQFLFSSGNHLYMLFTTDNSRSNSGFKILYESVTVDAYSCLDPGIPVNGLRYGQDFSIGSTVSFGCDSGYRLSHEEPLVCEKNHWWSHPLPTCDALCGGDVRGPGGTILSPGYPEVYPSSLNCTWTVEVSHGKGVQFTFNTFHLEDHHDYLLITENGSFVQPLARLTGAELPLPINAGLYGNFKAQLRFISDFSISYEGFNITFSEYNLEPCEDPGVPHYGRRNGYSFGIGDTLTFSCNLGYRLEGAPEIICLGGGRRMWSAPLPRCVAECGSSVINNEGILLSPNYPMNYENNHECIYSIQVQAGKGINISARTFHLAQGDILKIYDGKDNAAHMLGAFTGSSMLGLTLISTSNHLWLEFYSDAEATGEGFKLVYSSFELSHCEDPGVPQFGFKVNDQGHFSGSTITYKCDPGYTLHGSGVLKCMTGERRAWDNALPSCIAECGGRFKGETSGRILSPGYPFPYDNNLRCTWMVEVDSGNIISLQFLAFDTEASHDILRVWDGPPENEMSLREVSGSLLPENVHSTLNMVSIQFETDFYISKSGFAIEFSSSVATACRDPGVPMNGSRNGDGREPGDTVTFQCDPGYELQGDVKITCIQVENRYYWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSKDCDWLIAVNSDYVLSLAFISFSIEPNYDFLYIYDGADSNSPLIGSFQDSKLPERIESSSNTMYLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNVMNGTRLGSDYKLGSTVTFYCEAGYVLQGYSTLTCIMGDDGRPGWNRGLPSCQAPCGSRSTGTDGTVLSPNFPRNYTTGQSCVYTIAVPREFVLFGQFVLFQTSLNDVVDIYDGPTQQSSLLSSLSGSHSGESLPLSTGNQITIKFSTVGPETAKGFHFVYQAVPRTSATQCSSVPEPRFGKRIGNNFAVGASVMFECNPGYTLHGSTAIHCETVPDALAQWNDTLPTCIVPCGGILTMRKGTILSPGYPEPYDNNLNCVWKVSVPEGAGIQIQVVSFATEHNWDSLDFYDGADNNAPRLGSYSGTTIPQLLNSTSNNLYLNFVSDISVSAAGFHLEYTAIGLDTCPEPQTPTYGIKIGDRYMVGDVVMFQCEQGYSLQGNAHITCMPGPVRRWNYPVPLCLAQCGGAMTEVSGVILSPGFPGNYPSGLDCTWTITLPIGFGIHVQFLNFSTEAIHDYLEIRSGPSETGTVIDRFSGPQVPESLFSTTHETSFFFHSDYSQNKPGFHITYQAYQLQSCPDPRPFRNGIVIGSDFSVGMTVSFECLPGYSLIGETSLTCLHGISRNWNNPIPRCEALCGGNITSMNGTIFSPGHPAEYPNFQDCVWSVRVPPGNGIYINFTVLSTEPIYDYITVWDGPDQSSPQIGQFSGNTALESVYSTSNQILIKFHSDFSGSGFFVLSYHAYQLRVCQPPLEVANADILMEDNELEIGDIIRYRCHPGFTLVGSEILTCRLGERLQMDGHPPSCQVQCPAHDVRFDSSGVILSPGYPDSYPNLQMCSWSINVEKGYNITLFFEFFQTEKEYDILEVFDGPTIHSQTLATLSGDLPTPFNMTTSGHQLLLRWSADHGTNKKGFSIRYVGEYQTLYCSTPDSPLHGSISSQTGGHLNSLVRWTCDRGYRLIGKSTAVCKKTPFGFYDWDAPVPACQAVSCGVPKAPVNGGVLAMDYSVGTRVTYFCSDGYRLSSKELTSAVCQPDGTWSNHNKVPRCSVVVCPSIGSFSLEHGRWRIVNGSHYEYRTKIIFTCDPGYYRLGPAYIQCMANGAWSWKNERPHCQIISCGDLATPPSGKKIGTQTSFGATAIFTCDNGYMLVGSSVRECLSSGLWSGTETRCLAGHCGLPEQIVNGQVIGENFGYRDTVVYQCVSGFRLIGSSVRICQQDHNWSGQLPICVPISCGHPGSPIYGRTIGNGFNLNDVVSFSCNMGYVMEGPSRAQCQANRQWSQPPPTCKVVNCSDPGIPANSIRQSKIEHGNFTFGTVVFYDCNPGYYLFGSPVLTCQPTGQWDKPLPECIVVDCGHPGSPPNGLLSGDKFTFGATVRYSCTGGRQLKGESSRTCQLNGHWSAPMPFCSGDSSGTCGDPGTPSHGSRDESDFRIRSKVHFSCSVGYELFGSVERMCFPNGTWSGTQPSCKPVQCGNPGTPSNGRVYRLDGTTFSHSVIYSCMDGYLLSGSTTRQCQANGTWSGTAPNCTLINCGEPGVPANGLRYGEDFTIAQNITFMCQPGYTMEAESFSTITCTGNGTWNAPVPFCKAVTCTAPPPISNGLLEGRDFEWGTSVSYSCSPGYELSFPAILTCVGNGTWSGEVPQCLPKFCGDPGTPAFGSREGRSFIYQSEVSFSCMAPYIPVGSTTRICQTDGTWSGSQPRCIEPTRTTCENPGTPRYGSLNRTFGFKVGSMVAFQCQPGHLLQGSTTRLCQADLTWSGTQPECIPHSCKQPESPPHVDVVGMDLPSYGYTLIYSCQSGFFLSGGSEHRVCRSDGTWTGKMPVCRAGSKLSEKPIKPVPGTPSPKLNVPDDVFAPNYIWKGSYNYKGRKQPMTLSITSFNTTTGRVNVTLTSSNMELLLSGVYKSQEARLMLLVYHVKASSSSTLSKIKEEHWTLDGFVSAEPDGSTYVFQGFIQGKDYGQFGLQRLGLNMSESNNSSNPPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTTPKTQYTGCSVHENNNGQAAFENPMYNTKPEVKNVRFDPNLNTVCTMV", "length": 3269, "header": "tr|A0AC58I1A2-1|A0AC58I1A2_DANRE Computationally mapped isoform of CUB and sushi domain-containing protein 3 isoform X5 OS=Danio rerio OX=7955 GN=csmd3b PE=3 SV=1 CANONICAL=A0A8M9PNP5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 2960, "start_aa": "Thr", "end_pos": 2960, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr2960", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3018, "start_aa": "Thr", "end_pos": 3018, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3018", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3195, "start_aa": "Thr", "end_pos": 3195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3195", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 3382, "start_aa": "Thr", "end_pos": 3382, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr3382", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:572419", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:572419", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A4X5-1", "protein_name": "CUB and sushi domain-containing protein 3", "gene_name": "Csmd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKGSRKGESRAKESKPREPGTRRCAKCGRLDFILKKKMGIKSGFTFWNLVFLLTLSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPGFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSPLTLTASIGELEKHIRTATVANTPADVTVSSVTAVTSHRLSEEQRVQVRSLSDSGLDPNTSEDQLSPHQADTQSTSRRPRNAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSLLNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMRSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPDSPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGPIPRCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDPGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSELPSTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRVGFSFGVGDTLTFSCSLGYRLEGSSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSLQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDSEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENEMLLKEVSGSLIPDGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGQERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTVSVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRVLPSCHAPCGSRSTGSEGTVLSPNYPKNYSVDHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVFDGPTQQSPLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNDFAVGSLVLFECNPGYILHGSRAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQIVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKVGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIRLPIGFGVHLQFVNFSTETIHDYLEVRSGSSELSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNISMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSAAFNVTSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHSWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTATCQSDGTWSNHNKTPRCVVVTCPSINSFTLEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRTERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSGSETRCLAGHCGIPDLIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGIPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDPGMPGHGSRQESDFRTKSTVRFACDTGYILYGSEERTCLSNGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGNLPNCTIISCGDPGIPANGLRYGDDFVVGQNVSYMCQPGYTMELNGSRVRTCTTNGTWSGVMPTCRAVTCSTPPQISNGRLEGTNFDWGFSISYICSAGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPSQGKREGKSFIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLADLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSDMELLLSGVYKSQEARLMLHIYLIKVPANASVKKMKEENWAMDGFVSAEPDGATYVFQGFIKGKDYGQFGLQRLGLNTSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "length": 3703 }, "evidence": [ { "id": "RGD:1594530", "url": "https://alliancegenome.org/gene/RGD:1594530#orthology", "database": "AGR" }, { "id": "HGNC:19291", "url": "https://alliancegenome.org/gene/HGNC:19291#orthology", "database": "AGR" }, { "id": "MGI:2386403", "url": "https://alliancegenome.org/gene/MGI:2386403#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120214-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120214-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PNC7-1", "protein_name": "CUB and sushi domain-containing protein 3 isoform X1", "gene_name": "csmd3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKAADNEGWRGFLVLSHRGCIRCAHGTTMTIKTGFIIGNIVFCCILTCVQGFIYTCGGTLKGKNGTIESPGFPHGYPNGANCTWVIVAEERSRIHIVFQSFAVEEEYDFLSLYDGHPHPANFRTRLTGFQVPAPVTSTGSIFSLRLTSDFAVSAHGFKIYYEELQSSSCGNPGIPAKGILNGSSFNVGDRIRYHCVSGYTLDGHAQLTCVTSTSNVAVWDFPIPICRAEDTCGGTFRGASGTISSPDFQKDYQSSGECTWTILADPGDTISLVFTEFQMDSKLDSLEVEGSDPPTIWLSGINIPVPIVSNKNWLRLHFVTDNSHRHKGFSAQYQVKRSGDFKSRGVKLLPGKDNTSKFSIMNEGMVKQVSNFCPDPGEPENGKRIGTDYSIGATVQFTCDGDHVLQGSKSITCQRVAEVFAAWSDHRPVCKVKTCGMNLLGPSGTFTSPNFPIQYESNSQCVWIITASNPNKVIQINFEEFDLELGYDTLTVGDGGEVGDSKTIIQVLTGSFVPDLIVSMTHQMWLHLQSDESVGSIGFKINYKEIDKESCGDPGIPLYGLREGGGFSNGGVLRFECQFGFELIGERMISCQNNNQWSANIPICIFPCMSNFTAAMGTVLSPDYPEGYGNNLNCVWLIIAEAGSRIHLAFNDFDLEPPYDFLTVRDGDLADAVVLGRFSGAEVPSHLTSNSNILQLEFQADHSMSGRGFNITYSTFGHNECPDPGVPMNAKRFGNNFQLGSSISVVCEEGFIKTQGSDTIVCELEAGKVMWSGLIPKCEAPCGGHFTAPVGVILSPGWPGYYKDSLSCEWVIEAETGRSIKISFDRFQTELNYDFLEVHDGPNLLSPLIASLNGTQVPQFLFSSSNFLYLLFTTDNSRSNSGFKLFYESVTLDTHSCLDPGVPVNGVRYGQDLAIGSVVWFGCEPGYRLSHEEQLVCEKNHWWSHPLPTCDALCGGDVRGPEGIILSPGFPELYPNSLNCTWTLEVSHGKGVQFTFHAFHLEDHHDYLLLTENGSFVRPLARLTGSQRPPPVNAGLYGNFKAQLRFISDFSISFQGFNISFSEYDLEPCEDPGVPQFGRHSGGSFGIGDTLAFSCDPGYRLQGVPQISCLGGGRRIWSAPLPRCVAECGSTVSKNAGVLLSPNYPRNYDNNHECIYNIQVQAGKGINISASSFHLAQGDVLKLYDGPDNTADVLGAFSGSSMLSQSLTSTSNHLWLEFYSDQEDTAEGFKLAYTSFELSHCDEPGVPQFGSKVSDQGHFAGSVVTYHCDPGYSLHGSSILRCMTGERRTWDHPLPSCIAECGGSFKGESSGRILSPGYPFPYDNNLRCTWTIEVDSGNTVSLQFLAFDTEASHDILKVWDGHPENEMALKEVSGSLLPDGIHSTLNVVTIQFETDFYISKSGFAIDFSSSVATACRDPGTPMNGSRSGEGKEPGDTMTFACDPGYDLQGEPRITCIQVDNRFYWQPSPPTCIAPCGGNITGSSGFILSPNFPHPYPHSKDCDWFITVHPDYVISLAFISFSIEPNYDFLYIYDGPHSNSHLIGTFQDSKLPEKVESSSNIMHIAFRSDGSVSYTGFHLEYKAKLREACFDPGSVMNGTRLGGDYKLGSTVTFHCDPGYQLQGYSSLTCVMGATNRPEWNRALPSCQAPCGSRSTGSEGTILSPNYPRNYTTGQSCVYEISVPGEFVLFGQFMFFQTTSNDVVEIFDGASTESALLSSTYGSHSGEPLPLSSANEITIRFKTEGPNTAKGFHFVYQAVPRTSASQCSSVPEPRYGKRIGNDFGLGTVVLFECNPGYTLHGASAIRCEAVPNSLAQWNGTVPACVVACGGVLTTRRGTILSPGYPDPYDNHLNCVWKVFVPEGTGIQITVVTFSTEHNWDSLDFYDGIDSNAPRLGSYSGTTIPPLLNTTSNNLYLTFQTDMSVSGAGFHLEYTAIGLDSCPEPQTPGNGVKVGDRYFVGDVVSFHCEQGYTLKGSAYITCMPGPVRRWNYPAPLCLAQCGGFLTDLNGVILSPGFPGNYPSGLDCNWTVKLPIGFGIHLQFLNFSTESVHDYLEVRSGTLDSGSVIDRFSGPVVPESFFSTTHETSFFFHSDYSQNKPGFHITYEAYELQRCPDPRPFRNGVVIGSDFGVGMTISFQCLPGYTLLGESSLTCLHGVSRNWNHPVPRCEALCGGNITVLNGTIYSPGHPADYPNLKDCIWSIRVPPGNGIHINFTVLNTEPIYDYITIWDGPDQTSPQIGQFSGSLPQEPVSSTSNHILLKFHSDFSTSGFFVLRYHAYQLRVCQPPPPVANAEILAEDDEFQIGDIIRYRCLPGFTLLGSEILTCRLGERLQMDGPPPVCQVQCPDNEVLFDSTGVILSPGYPDSYPNLQMCSWMINVEKGYNITLHFQLFQTEKEFDILEIFDGPNIYSQSLAVLSGDLSVPFNITTTGHQLFLRWSSDHGTNKKGFRITYVGEYQTMYCSTPDSPQHGFVLSQTGGHVNSVVRWACDRGFRLIGKNMAVCKRTEIGFLAWDSSVPACQAVSCGMPVAPVNGGVLAADYSAGTRATYFCNDGFRLSSKEVTSTVCQADGTWSSHNKIPRCTVVVCPSIGSFTLDHGKWRIVNGSRYEYGTKVAFTCNAGYYRLGPAHIHCTSNGTWSWRNERPRCKVISCGELPTPPNGKKIGTQTTFGATAIFTCNSGFILVGSTVRECLPSGLWSGTETHCLAGHCGIPERIVNGQVIGENFGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVSISCGHPGSPIYGRTVGDGFNLNDVVTFFCNKGYILEGPSEAQCQSDRQWSQHPPTCRVVNCTDPGIPANSIRKSKIEYGNFTFGTVVSYDCNPGYYLFGSSVLTCQPVGYWDKPLPECLEVDCGHPGSPPHAVVTGDKFTFGSTVHYRCLEDRVLIGESTRACQLNGQWGGSQPHCSGDKRGACGDPGTPAHATREESSFQQHAKVRFTCSTGHTLYGSAERICFPNGTWSGRQPTCKPVQCGNPGTPANGRVSHVSGTTFSHSIIYSCVEGYRLSGSPTRQCLANGTWSGGEPNCTLISCGDSGVPASGLRTGEDFTVGHNVSYSCQPGFMMENGSSAIRTCTHNGTWSGSLPSCQAVTCSPPPAVSNGEVEGSVFEWGVSVSYRCMMGYELSFPAVLTCAGNGSWSGEIPLCLPKFCGDPGIPSRARREGQSFIFKAEVMFSCSAPYVLVGSSTRTCQADATWSGTQPRCIEPTRTTCENPGTPEFGSLNSSLGFKVGSTVKFVCQTGHLLLGSTTRTCQQDLTWSGSQPECIPHSCKQPKTPPHANVLGMDLPSFGYTLLYSCQPGFILTGGSEHRACRPDGSWTGKVPVCRAGSKTSEKVITPVQGTSSPKVNVPDDVFAPTFLWKGSFEYKGAKQPMTLTITSFNATTGKVNATLTNRHSELLLSGVYKSRDARLTLRLYHMKTLLKNTYSKTTEESMIMDGFVSADHEGNTYLFQGFIQGRDYGPFGLQRQGLNVLEPTRSPEIPPRTNSSSVAIAILVPFFALIFAGFGFYLYKQRKSDKAEYSGCSVHENNNGQATFENPMYNTNSKSIEGKVVRFDPNLNTVCTMV", "length": 3598 }, "evidence": [ { "id": "RGD:1594530", "url": "https://alliancegenome.org/gene/RGD:1594530#orthology", "database": "AGR" }, { "id": "HGNC:19291", "url": "https://alliancegenome.org/gene/HGNC:19291#orthology", "database": "AGR" }, { "id": "MGI:2386403", "url": "https://alliancegenome.org/gene/MGI:2386403#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7Z407-1", "protein_name": "CUB and sushi domain-containing protein 3", "gene_name": "CSMD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGIRKGESRAKESKPWEPGKRRCAKCGRLDFILMKKMGIKSGFTFWNLVFLLTVSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPSFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSTLTHTTSTGELEEHNRTTTGAIAVASTPADVTVSSVTAVTIHRLSEEQRVQVTSLRNSGLDPNTSKDGLSPHPADTQSTRRRPRHAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSILNEGGIKTASNLCPDPGEPENGKRIGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMSSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPESPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGLIPKCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDSGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSDLPPTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRIGFNFGIGDTLTFSCSSGYRLEGTSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSIQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDTEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENDMLLKEISGSLIPEGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGEERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTITVNADYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRALPSCHAPCGSRSTGSEGTVLSPNYPKNYSVGHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVYDGPTQQSSLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNEFAVGSSVLFDCNPGYILHGSIAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKIGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTINLPIGFGVHLQFVNFSTETIHDYLEVRSGSSETSTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNITMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSSAFNITSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHAWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTAVCQSDGTWSNHNKTPRCVVVTCPSINSFILEHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRNERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSESETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPMCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGVPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQSSRTCQLNGHWSGSQPHCSGDATGTCGDPGTPGHGSRQESNFRTKSTVRYACDTGYILHGSEERTCLANGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCMEGYILSGPSVRQCTANGTWSGTLPNCTIISCGDPGIPANGLRYGDDYVVGQNVSYMCQPGYTMELNGSRIRTCTINGTWSGVMPTCRAVTCPTPPQISNGRLEGTNFDWGFSISYICSPGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPAQGKREGKSFIYQSEVSFSCNFPFILVGSSTRICQADGTWSGSSPHCIEPTQTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPETPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPICEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSNMELLLSGVYKSQEARLMLRIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIQGKDYGQFGLQRLGLNMSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "length": 3707 }, "evidence": [ { "id": "RGD:1594530", "url": "https://alliancegenome.org/gene/RGD:1594530#orthology", "database": "AGR" }, { "id": "HGNC:19291", "url": "https://alliancegenome.org/gene/HGNC:19291#orthology", "database": "AGR" }, { "id": "MGI:2386403", "url": "https://alliancegenome.org/gene/MGI:2386403#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120214-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120214-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80T79-3", "protein_name": "CUB and sushi domain-containing protein 3", "gene_name": "Csmd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGSRKGESRAKESKPREPGTRRCAKCGRLDFILKKKMGIKSGFTFWNLVFLLTLSCVKGFIYTCGGTLKGLNGTIESPGFPYGYPNGANCTWVIIAEERNRIQIVFQSFALEEEYDYLSLYDGHPHPTNFRTRLTGFHLPPPVTSTKSVFSLRLTSDFAVSAHGFKVYYEELQSSSCGNPGVPPKGVLYGTRFDVGDKIRYSCVTGYILDGHPQLTCIANSVNTASWDFPVPICRAEDACGGTMRGSSGIISSPGFPNEYHNNADCTWTIVAEPGDTISLIFTDFQMEEKYDYLEIEGSEPPTIWLSGMNIPPPIISNKNWLRLHFVTDSNHRYRGFSAPYQGSSPLTLTASIGELEEHIRTATGAIDVASTPADVTVSSVTAVTSHRLSEEQRVQVRSLSDSGLDPNTPEDQLSPHQADTQSTSRRPRNAEQIERTKELAVVTHRVKKAIDFKSRGFKLFPGKDNSNKFSLLNEGGIKTASNLCPDPGEPENGKRFGSDFSLGSTVQFSCDEDYVLQGAKSITCQRIAEVFAAWSDHRPVCKVKTCGSNLQGPSGTFTSPNFPFQYDSNAQCVWVITAVNTNKVIQINFEEFDLEIGYDTLTIGDGGEVGDPRTVLQVLTGSFVPDLIVSMRSQMWLHLQTDESVGSVGFKVNYKEIEKESCGDPGTPLYGIREGDGFSNRDVLRFECQFGFELIGEKSIVCQENNQWSANIPICIFPCLSNFTAPMGTVLSPDYPEGYGNNLNCIWTIISDPGSRIHLSFNDFDLESQFDFLAVKDGDSPDSPILGTFTGAEVPSHLTSNSHILRLEFQADHSMSGRGFNITYNTFGHNECPDPGIPINARRFGDNFQLGSSISVICEEGFIKTQGTETITCILMDGKVMWSGPIPRCGAPCGGHFSAPSGVILSPGWPGYYKDSLNCEWVIEAEPGHSIKITFERFQTELNYDVLEVHDGPNLLSPLLGSYNGTQVPQFLFSSSNFIYLLFTTDNSRSNNGFKIHYESVTVNTYSCLDPGIPVHGRRYGHDFSIGSTVSFSCDPGYRLSHEEPLLCEKNHWWSHPLPTCDALCGGDVRGPSGTILSPGYPEFYPNSLNCTWTVDVTHGKGVQFNFHTFHLEDHHDYLLITENGSFTQPLARLTGSELPSTINAGLYGNFRAQLRFISDFSISYEGFNITFSEYNLEPCEDPGIPQYGSRVGFSFGVGDTLTFSCSLGYRLEGSSEIICLGGGRRVWSAPLPRCVAECGASATNNEGILLSPNYPLNYENNHECIYSLQVQAGKGINISARTFHLAQGDVLKIYDGKDKTTHLLGAFTGASMRGLTLSSTSNQLWLEFNSDSEGTDEGFQLVYTSFELSHCEDPGIPQFGYKISDQGHFAGSTIIYGCNPGYTLHGSSLLKCMTGERRAWDYPLPSCIAECGGRFKGESSGRILSPGYPFPYDNNLRCMWMIEVDPGNIVSLQFLAFDTEASHDILRVWDGPPENEMLLKEVSGSLIPDGIHSTLNIVTIQFDTDFYISKSGFAIQFSSSVATACRDPGVPMNGTRNGDGREPGDTVVFQCDPGYELQGQERITCIQVENRYFWQPSPPVCIAPCGGNLTGSSGFILSPNFPHPYPHSRDCDWTISVNTDYVISLAFISFSIEPNYDFLYIYDGPDSNSPLIGSFQDSKLPERIESSSNTMHLAFRSDGSVSYTGFHLEYKAKLRESCFDPGNIMNGTRLGMDYKLGSTVTYYCDAGYVLQGYSTLTCIMGDDGRPGWNRVLPSCHAPCGSRSTGSEGTVLSPNYPKNYSVDHNCVYSIAVPKEFVVFGQFVFFQTSLHDVVEVFDGPTQQSPLLSSLSGSHSGESLPLSSGNQITIRFTSVGPITAKGFHFVYQAVPRTSSTQCSSVPEPRFGRRIGNDFAVGSLVLFECNPGYILHGSRAIRCETVPNSLAQWNDSLPTCIVPCGGILTKRKGTILSPGYPEPYDNNLNCVWKITVPEGAGIQVQVVSFATEHNWDSLDFYDGGDNNAPRLGSYSGTTIPHLLNSTSNNLYLNFQSDISVSAAGFHLEYTAIGLDSCPEPQTPSSGIKVGDRYMVGDVVSFQCDQGYSLQGHSHITCMPGPVRRWNYPIPICLAQCGGAMSDFSGVILSPGFPGNYPSSLDCTWTIKLPIGFGVHLQFVNFSTETIHDYLEVRSGSSEISTVIGRLSGPQIPSSLFSTTHETSLYFHSDYSQNKQGFHIVYQAYQLQSCPDPRPFRNGFVIGNDFTVGQTISFECFPGYTLIGNSALTCLHGVSRNWNHPLPRCEALCGGNITAMNGTIYSPGYPDEYPNFQDCFWLVRVPPGNGIYINFTVLQTEPIYDFITVWDGPDQNSPQIGQFSGNTALESVYSTSNQILIKFHSDFTTSGFFVLSYHAYQLRVCQPPPPVPNAEILTEDDEFEIGDIIRYQCLPGFTLVGNAILTCRLGERLQMDGAPPVCQVLCPANELRLDSTGVILSPGYPDSYPNLQMCAWSISVEKGYNISMFVEFFQTEKEFDVLQVYDGPNIQSPVLISLSGDYSAAFNVTSNGHEVFLQWSADHGNNKKGFRIRYIAFYCSTPESPPHGYIISQTGGQLNSVVRWACDRGFRLVGKSSAVCRKSSYGYHSWDAPVPACQAISCGIPKAPTNGGILTTDYLVGTRVTYFCNDGYRLSSKELTTATCQSDGTWSNHNKTPRCVVVTCPSINSFTLDHGRWRIVNGSHYEYKTKVVFSCDPGYHGLGPASIECLPNGTWSWRTERPYCQIISCGELPTPPNGNKIGTQTSYGSTAIFTCDLGFMLVGSAVRECLSSGLWSGSETRCLAGHCGIPELIVNGQVIGENYGYRDTVVYQCNPGFRLIGSSVRICQQDHNWSGQLPSCVPVSCGHPGSPIYGRTSGNGFNFNDVVTFSCNIGYLMQGPTKAQCQANRQWSHPPPVCKVVNCSDPGIPANSKRESKIEHGNFTYGTVVFYDCNPGYFLFGSSVLICQPNGQWDKPLPECIMIDCGHPGIPPNAVLSGEKYTFGSTVHYSCTGKRSLLGQASRTCQLNGHWSGSQPHCSGDTTGTCGDPGTPGHGSRQESDFRTKSTVRFACDTGYILYGSEERTCLSNGSWTGRQPECKAVQCGNPGTTANGKVFRIDGTTFSSSVIYSCLEGYILSGPSVRQCTANGTWSGSLPNCTIISCGDPGIPANGLRYGDDFVVGQNVSYMCQPGYTIELNGSRVRTCTTNGTWSGVMPTCRAVTCSTPPQISNGRLEGTNFDWGFSISYICSAGYELSFPAVLTCVGNGTWSGEVPQCLPKFCGDPGIPSQGKREGKSFIYQSEVSFSCNSPFILVGSSTRLCQTDGTWSGSSPHCIEPTRTSCENPGVPRHGSQNNTFGFQVGSVVQFHCKKGHLLQGSTTRTCLPDLTWSGIQPECIPHSCKQPESPAHANVVGMDLPSHGYTLIYTCQPGFFLAGGTEHRVCRSDNTWTGKVPVCEAGSKILVKDPRPALGTPSPKLSVPDDVFAQNYIWKGSYNFKGRKQPMTLTVTSFNASTGRVNATLSNSDMELLLSGVYKSQEARLMLHIYLIKVPAHASVKKMKEENWAMDGFVSAEPDGATYVFQGFIKGKDYGQFGLQRLGLNTSEGSNSSNQPHGTNSSSVAIAILVPFFALIFAGFGFYLYKQRTAPKTQYTGCSVHENNNGQAAFENPMYDTNAKSVEGKAVRFDPNLNTVCTMV", "length": 3707 }, "evidence": [ { "id": "RGD:1594530", "url": "https://alliancegenome.org/gene/RGD:1594530#orthology", "database": "AGR" }, { "id": "HGNC:19291", "url": "https://alliancegenome.org/gene/HGNC:19291#orthology", "database": "AGR" }, { "id": "MGI:2386403", "url": "https://alliancegenome.org/gene/MGI:2386403#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120214-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120214-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VYR4-1", "protein_name": "Furrowed, isoform C", "gene_name": "fw", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFCCNIPVDASVATSTSTSISTYPLQRATKRAMTPPNAMALIMLLLLALCAAGNGQICGPPAVPLNAKVRTITVDSQIAEAHYECDAGYELFGPSAVKCDRRTGWDRDLPFCGVNVAYRKPVNQSSYTRSGPASYANDGKPGNKNPDGQECSETQKEPSPWWRVDLLTPQAVHVVRITTRGCCGHQPLQDLEIRVGNSSADLQRNPLCAWYPGTLDEGVVKTFTCARPLVGQYVAIQLVGVEGSLSLCEVETFTNDEFSVDRCLSPKIGVDTVVTTFSKTCYDFHITKGESFDKAQAICKQTGGDLVHDFRGATSSYILSELERRKSELKPQLVWIGAQKEPGITSRTWKWVNGDVVQKPTWGKDQPNNYNGEQNCVVLDGGRNWLWNDVGCNLDYLHFICQHSPLSCGSPDAQQNTTVMGKKFTLGEKIQYTCPKGHSLLGQTERECRLDGTWSGSSPTCKYVDCGSLPELKFGSIHMSEERTSFGVVATYSCHENYTLIGNENRTCAMDGWSGKQPECLVDWCPDPQPIAGGDVRFNDKRAGSTATYVCEPGYVLVGEAIISCGLGGEWSSKTPSCRFVDCGAPARPNRGIAILLNGTTTVNSVVKYECDEDHWLDGQSELYCTREGKWSGEAPVCELVTCETPSVPSGSFVIGYDYNVHSKIQYNCDPGHIMHGTPVLECLDSGEWSADAPYCEYIDCGTILPIPYGSHKYVTNTTYVGSEVVFSCSQSHKLSGVLKRTCLESAVWSDASPKCEEIRCPEPKLAAHSLLSVTGNDRMYGRTLIRTSESSQNTAQTYKIGALAKYRCERGYKMVGEALATCTDSGQWSGTIPECVYVECGAPEGINNGKVVLATNATYYGAAVLYECNVNFKLNGVSRRLCTEHGNWSHEAPECVEVVCDTPNINENLIVEAGPRAVGSVATFKCAKGRIMMGNDTRVCQKNGKWTGKSPTCRPVDCGRPLAIENGRVIVVNDSTLYGGSAEYHCIPNYNRIGQYLRKCTEDGAWSGKQPRCELATAEGQETSELGTGVGIGATVIVALLVIFGLIFLYRNKARPVKNTENVQAAETKDERNAAVMSYSTLEANNRMHMDNNPSATFNTFHGGAGGRSNGGGNPDANSNGERLNNNRSENIYDQIPNEQFYDAPYEMRTNDEVYEPEPVASNVITINGISVR", "length": 1174 }, "evidence": [ { "id": "RGD:1594530", "url": "https://alliancegenome.org/gene/RGD:1594530#orthology", "database": "AGR" }, { "id": "HGNC:19291", "url": "https://alliancegenome.org/gene/HGNC:19291#orthology", "database": "AGR" }, { "id": "MGI:2386403", "url": "https://alliancegenome.org/gene/MGI:2386403#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNP5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNP5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNP5" } ], "pmid": "" } ] }, { "name": 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The reference sequence was derived from JBMGRA010000001.1. On Aug 5, 2025 this sequence version replaced XP_694356.4.", "evidence": [ { "database": "RefSeq", "id": "NP_001429340", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429340" } ] }, { "annotation": "Knockdown of son in zebrafish resulted in severe malformation of the spine, brain, and eyes", "evidence": [ { "database": "RefSeq", "id": "NP_001429340", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429340" }, { "database": "PubMed", "id": "27545680", "url": "https://glygen.org/publication/PubMed/27545680" } ] }, { "annotation": "Son is necessary for proper vertebrate blood development. 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"MATNIEQIFRDFVMNKIKEIEDETQENSVTDEPQPEPVTETKEDKINEDKTNPPTDKVTHIDVQADHGKEDTSTKHRKSKKHKKHKSKKKRKKRKEGKDSSSDTESDKQNQESGKKKKRKKKKKSKHADKAKRSGSRSESSSASDSESESESKPSSENTKSAGKTELKDKSALDKPQELPDIIPKIETSVHKSTEKERPKEKKRSSSRASKSKEASKGRRSRSRSPRRRSGHRSRSRSVKRQRRSKSTSRSRNNSKKSSHQPRERSRSRSKRRKDRSRSRSVRRKHSRSRSRSRRTRSRSVVILRKNRRSASRSRSSRCRSKSQSRSKSPKSRSVSKSKDRPIDSESKNHTVDSNKSSDTNKDGENPTVNSECNLSDAAPSAGFNTVVSSGSWRPIPLLAEPPKSSQKCLTPEVPLEVASVHEEPSTLKTDPECSANPDKKEPNANPTTTTETSANSSKSPNPKTSSTSKRSASKKRKSRSKSSERKSHKSRTRSKRSKSKSPKKKRSRSRSQGHRNKSRTPDRSRRSKSRKRSRSRSRRRSRSGSRWRRGFGSLSQRDRWKREPSRSPVLILRKKRSTSRTRRSTSKTPPRLTELDKDQLLEIAKANAAAMCAKAGVPIPDSLRPRAILQLPLPNANSASLSLPVMPNMAMNAAVASMTAATMTAALSSIGALASFPQFAPLPTIVNKPPSSATPNLASIEEAKKKVTKQANSFSIKELTERCKKIAESKEEMAIAKPHVSDDEEDEKLFGASLKENKGIAFSLGNTSIKPGVRTEAAFAKEFPVSSGSQHRKKEGDGAYGEWVPVEKKAEKPSASSSSATEETSKDSDSVFPEAPSQPVDITLAVSERAVAQKRLAENPFDINAMCMLNRAQEQVDAWAQSNTIPGLFTGSTGAQVLSSDELSNSGPQAWIKKDQFLRAAPVSGGMGEFLMRKMGWRSGEGLGKHREGTVEPIIIDFKTDRKGLVAEGEKTQKSGNIVVMKDLLGKHPVSALMEMCNKKKWPQPEFVMVHHSGPDHRKNFLFKVVVNGSDYQPQSASPNKKHAKAMAATVALQAMGEVAGDGVHSGPVFTAASSSST", "length": 1079, "header": "tr|A0A8N7UR74-1|A0A8N7UR74_DANRE Isoform 1 of Protein SON isoform X1 OS=Danio rerio OX=7955 GN=sonb PE=4 SV=1 CANONICAL=A0A8N7UR74-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UR74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR74/entry#A0A8N7UR74-1", "sequence": { "sequence": "MATNIEQIFRDFVMNKIKEIEDETQENSVTDEPQPEPVTETKEDKINEDKTNPPTDKVTHIDVQADHGKEDTSTKHRKSKKHKKHKSKKKRKKRKEGKDSSSDTESDKQNQESGKKKKRKKKKKSKHADKAKRSGSRSESSSASDSESESESKPSSENTKSAGKTELKDKSALDKPQELPDIIPKIETSVHKSTEKERPKEKKRSSSRASKSKEASKGRRSRSRSPRRRSGHRSRSRSVKRQRRSKSTSRSRNNSKKSSHQPRERSRSRSKRRKDRSRSRSVRRKHSRSRSRSRRTRSRSVVILRKNRRSASRSRSSRCRSKSQSRSKSPKSRSVSKSKDRPIDSESKNHTVDSNKSSDTNKDGENPTVNSECNLSDAAPSAGFNTVVSSGSWRPIPLLAEPPKSSQKCLTPEVPLEVASVHEEPSTLKTDPECSANPDKKEPNANPTTTTETSANSSKSPNPKTSSTSKRSASKKRKSRSKSSERKSHKSRTRSKRSKSKSPKKKRSRSRSQGHRNKSRTPDRSRRSKSRKRSRSRSRRRSRSGSRWRRGFGSLSQRDRWKREPSRSPVLILRKKRSTSRTRRSTSKTPPRLTELDKDQLLEIAKANAAAMCAKAGVPIPDSLRPRAILQLPLPNANSASLSLPVMPNMAMNAAVASMTAATMTAALSSIGALASFPQFAPLPTIVNKPPSSATPNLASIEEAKKKVTKQANSFSIKELTERCKKIAESKEEMAIAKPHVSDDEEDEKLFGASLKENKGIAFSLGNTSIKPGVRTEAAFAKEFPVSSGSQHRKKEGDGAYGEWVPVEKKAEKPSASSSSATEETSKDSDSVFPEAPSQPVDITLAVSERAVAQKRLAENPFDINAMCMLNRAQEQVDAWAQSNTIPGLFTGSTGAQVLSSDELSNSGPQAWIKKDQFLRAAPVSGGMGEFLMRKMGWRSGEGLGKHREGTVEPIIIDFKTDRKGLVAEGEKTQKSGNIVVMKDLLGKHPVSALMEMCNKKKWPQPEFVMVHHSGPDHRKNFLFKVVVNGSDYQPQSASPNKKHAKAMAATVALQAMGEVAGDGVHSGPVFTAASSSST", "length": 1079, "header": "tr|A0A8N7UR74-1|A0A8N7UR74_DANRE Isoform 1 of Protein SON isoform X1 OS=Danio rerio OX=7955 GN=sonb PE=4 SV=1 CANONICAL=A0A8N7UR74-1" }, "locus": {} }, { "isoform_ac": "A0AB32TIB5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR74/entry#A0AB32TIB5-1", "sequence": { "sequence": "MATNIEQIFRDFVMNKIKEIEDETQENSVTDEPQPEPVTETKEDKINEDKTNPPTDKVTHIDVQADHGKEDTSTKHRKSKKHKKHKSKKKRKKRKEGKDSSSDTESDKQNQESGKKKKRKKKKKSKHADKAKRSGSRSESSSASDSESESESKPSSENTKSAGKTELKDKSALDKPQELPDIIPKIETSVHKSTEKERPKEKKRSSSRASKSKEASKGRRSRSRSPRRRSGHRSRSRSVKRQRRSKSTSRSRNNSKKSSHQPRERSRSRSKRRKDRSRSRSVRRKHSRSRSRSRRTRSRSVVILRKNRRSASRSRSSRCRSKSQSRSKSPKSRSVSKSKDRPIDSESKNHTVDSNKSSDTNKDGENPTVNSECNLSDAAPSAGFNTVVSSGSWRPIPLLAEPPKSSQKCLTPEVPLEVASVHEEPSTLKTDPECSANPDKKEPNANPTTTTETSANSSKSPNPKTSSTSKRSASKKRKSRSKSSERKSHKSRTRSKRSKSKSPKKKRSRSRSQGHRNKSRTPDRSRRSKSRKRSRSRSRRRSRSGSRWRRGFGSLSQRDRWKREPSRSPVLILRKKRSTSRTRRSTSKTPPRLTELDKDQLLEIAKANAAAMCAKAGVPIPDSLRPRAILQLPLPNANSASLSLPVMPNMAMNAAVASMTAATMTAALSSIGALASFPQFAPLPTIVNKPPSSATPNLASIEEAKKKVTKQANSFSIKELTERCKKIAESKEEMAIAKPHVSDDEEDEKLFGASLKENKGIAFSLGNTSIKPGVRTEAAFAKEFPVSSGSQHRKKEGDGAYGEWVPVEKKAEKPSASSSSATEETSKDSDSVFPEAPSQPVDITLAVSERAVAQKRLAENPFDINAMCMLNRAQEQVDAWAQSNTIPGLFTGSTGAQVLSSDELSNSGPQAWIKKCLMREGRKEEDVK", "length": 928, "header": "tr|A0AB32TIB5-1|A0A8N7UR74_DANRE Computationally mapped isoform of Protein SON isoform X1 OS=Danio rerio OX=7955 GN=sonb PE=4 SV=1 CANONICAL=A0A8N7UR74-1" }, "locus": {} }, { "isoform_ac": "A0AB32TK70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR74/entry#A0AB32TK70-1", "sequence": { "sequence": "MATNIEQIFRDFVMNKIKEIEDETQENSVTDEPQPEPVTETKEDKINEDKTNPPTDKVTHIDVQADHGKEDTSTKHRKSKKHKKHKSKKKRKKRKEGKDSSSDTESDKQNQESGKKKKRKKKKKSKHADKAKRSGSRSESSSASDSESESESKPSSENTKSAGKTELKDKSALDKPQELPDIIPKIETSVHKSTEKERPKEKKRSSSRASKSKEASKGRRSRSRSPRRRSGHRSRSRSVKRQRRSKSTSRSRNNSKKSSHQPRERSRSRSKRRKDRSRSRSVRRKHSRSRSRSRRTRSRSVVILRKNRRSASRSRSSRCRSKSQSRSKSPKSRSVSKSKDRPIDSESKNHTVDSNKSSDTNKDGENPTVNSECNLSDAAPSAGFNTVVSSGSWRPIPLLAEPPKSSQKCLTPEVPLEVASVHEEPSTLKTDPECSANPDKKEPNANPTTTTETSANSSKSPNPKTSSTSKRSASKKRKSRSKSSERKSHKSRTRSKRSKSKSPKKKRSRSRSQGHRNKSRTPDRSRRSKSRKRSRSRSRRRSRSGSRWRRGFGSLSQRDRWKREPSRSPVLILRKKRSTSRTRRSTSKTPPRLTELDKDQLLEIAKANAAAMCAKAGVPIPDSLRPRAILQLPLPNANSASLSLPVMPNMAMNAAVASMTAATMTAALSSIGALASFPQFAPLPTIVNKPPSSATPNLASIEEAKKKVTKQANSFSIKELTERCKKIAESKEEMAIAKPHVSDDEEDEKLFGASLKENKGIAFSLGNTSIKPGVRTEAAFAKEFPVSSGSQHRKKEGDGAYGEWVPVEKKAEKPSASSSSATEETSKDSDSVFPEAPSQPVDITLAVSERAVAQKRLAENPFDINAMCMLNRAQEQVDAWAQSNTIPGLFTGSTGAQVLSSDELSNSGPQAWIKKGQSL", "length": 919, "header": "tr|A0AB32TK70-1|A0A8N7UR74_DANRE Computationally mapped isoform of Protein SON isoform X1 OS=Danio rerio OX=7955 GN=sonb PE=4 SV=1 CANONICAL=A0A8N7UR74-1" }, "locus": {} }, { "isoform_ac": "A0AB32TLP6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR74/entry#A0AB32TLP6-1", "sequence": { "sequence": "MATNIEQIFRDFVMNKIKEIEDETQENSVTDEPQPEPVTETKEDKINEDKTNPPTDKVTHIDVQADHGKEDTSTKHRKSKKHKKHKSKKKRKKRKEGKDSSSDTESDKQNQESGKKKKRKKKKKSKHADKAKRSGSRSESSSASDSESESESKPSSENTKSAGKTELKDKSALDKPQELPDIIPKIETSVHKSTEKERPKEKKRSSSRASKSKEASKGRRSRSRSPRRRSGHRSRSRSVKRQRRSKSTSRSRNNSKKSSHQPRERSRSRSKRRKDRSRSRSVRRKHSRSRSRSRRTRSRSVVILRKNRRSASRSRSSRCRSKSQSRSKSPKSRSVSKSKDRPIDSESKNHTVDSNKSSDTNKDGENPTVNSECNLSDAAPSAGFNTVVSSGSWRPIPLLAEPPKSSQKCLTPEVPLEVASVHEEPSTLKTDPECSANPDKKEPNANPTTTTETSANSSKSPNPKTSSTSKRSASKKRKSRSKSSERKSHKSRTRSKRSKSKSPKKKRSRSRSQGHRNKSRTPDRSRRSKSRKRSRSRSRRRSRSGSRWRRGFGSLSQRDRWKREPSRSPVLILRKKRSTSRTRRSTSKTPPRLTELDKDQLLEIAKANAAAMCAKAGVPIPDSLRPRAILQLPLPNANSASLSLPVMPNMAMNAAVASMTAATMTAALSSIGALASFPQFAPLPTIVNKPPSSATPNLASIEEAKKKVTKQANSFSIKELTERCKKIAESKEEMAIAKPHVSDDEEDEKLFGASLKENKGIAFSLGNTSIKPGVRTEAAFAKEFPVSSGSQHRKKEGDGAYGEWVPVEKKAEKPSASSSSATEETSKDSDSVFPEAPSQPVDITLAVSERAVAQKRLAENPFDINAMCMLNRAQEQVDAWAQSNTIPGLFTGSTGAQVLSSDELSNSGPQAWIKKQMH", "length": 918, "header": "tr|A0AB32TLP6-1|A0A8N7UR74_DANRE Computationally mapped isoform of Protein SON isoform X1 OS=Danio rerio OX=7955 GN=sonb PE=4 SV=1 CANONICAL=A0A8N7UR74-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "De Novo Mutations in SON Disrupt RNA Splicing of Genes Essential for Brain Development and Metabolism, Causing an Intellectual-Disability Syndrome.", "journal": "American journal of human genetics", "date": "2016", "authors": "Kim JH, Shinde DN, Reijnders MRF, Hauser NS, Belmonte RL, Wilson GR, Bosch DGM, Bubulya PA, Shashi V, Petrovski S, Stone JK, Park EY, Veltman JA, Sinnema M, Stumpel CTRM, Draaisma JM, Nicolai J, Yntema HG, Lindstrom K, de Vries BBA, Jewett T, Santoro SL, Vogt J, Bachman KK, Seeley AH, Krokosky A, Turner C, Rohena L, Hempel M, Kortum F, Lessel D, Neu A, Strom TM, Wieczorek D, Bramswig N, Laccone FA, Behunova J, Rehder H, Gordon CT, Rio M, Romana S, Tang S, El-Khechen D, Cho MT, McWalter K, Douglas G, Baskin B, Begtrup A, Funari T, Schoch K, Stegmann APA, Stevens SJC, Zhang DE, Traver D, Yao X, MacArthur DG, Brunner HG, Mancini GM, Myers RM, Owen LB, Lim ST, Stachura DL, Vissers LELM, Ahn EYE", "evidence": [ { "database": "RefSeq", "id": "NP_001429340", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429340" } ], "reference": [ { "type": "PubMed", "id": "27545680", "url": "https://glygen.org/publication/PubMed/27545680" } ] }, { "title": "son is necessary for proper vertebrate blood development.", "journal": "PloS one", "date": "2021", "authors": "Belmonte Rebecca L, Engbretson Isabella L, Kim Jung-Hyun, Cajias Illiana, Ahn Eun-Young Erin, Stachura David L", "evidence": [ { "database": "RefSeq", "id": "NP_001429340", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429340" } ], "reference": [ { "type": "PubMed", "id": "33630943", "url": "https://glygen.org/publication/PubMed/33630943" } ] } ], "pathway": [ { "id": "dre:565999", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565999", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR74", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR74", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR74" } ], "pmid": "" }, { "name": "head development", "id": "GO:0060322", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060322", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR74", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR74" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR74", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR74" } ], "pmid": "" }, { "name": "regulation of mRNA splicing, via spliceosome", "id": "GO:0048024", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048024", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR74", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1029, "end_pos": 1031, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 374, "end_pos": 376, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 517, "end_pos": 519, "annotation": "n_glycosylation_sequon" }, { "start_pos": 767, "end_pos": 769, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UR74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR74" }, { "id": "PS50137", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50137" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DRBM", "eco_id": "ECO_0000259", "start_pos": 989, "end_pos": 1059, "start_aa": "His", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UR74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR74" }, { "id": "PS50174", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50174" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-patch", "eco_id": "ECO_0000259", "start_pos": 925, "end_pos": 971, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1029, "end_pos": 1031 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 374, "end_pos": 376 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 517, "end_pos": 519 }, { "start_pos": 767, "end_pos": 769 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PLH6-1", "uniprot_ac": "A0A8M9PLH6", "uniprot_id": "A0A8M9PLH6_DANRE", "mass": { "chemical_mass": 110785.0, "monoisotopic_mass": 110785.0 }, "refseq": { "ac": "XP_009300157", "name": "uncharacterized protein wu:fi75a02 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009300157" }, "gene_names": [ { "name": "wu:fi75a02", "type": "recommended", "evidence": [ { "id": "A0A8M9PLH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH6" } ] }, { "name": "wu:fi75a02", "type": "synonym", "evidence": [ { "id": "XP_009300157", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009300157" }, { "id": "A0A8M9PLH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH6" } ] } ], "protein_names": [ { "name": "Uncharacterized protein wu:fi75a02 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PLH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein wu:fi75a02 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_009300157", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009300157" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009300157", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009300157" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-6395", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6395", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "569699", "url": "https://www.ncbi.nlm.nih.gov/gene/569699", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028149", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028149", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569699", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569699", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PLH6", "url": "https://www.orthodb.org/?gene=A0A8M9PLH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14522", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14522", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14522:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14522:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15386", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15386", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009300157", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009300157", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TKG7", "url": "https://www.uniprot.org/uniprotkb/A0AB32TKG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TKG7-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TKG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JM78", "url": "https://www.uniprot.org/uniprotkb/A0AC58JM78", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JM78-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JM78-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JM97", "url": "https://www.uniprot.org/uniprotkb/A0AC58JM97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JM97-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JM97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-6395", "url": "https://zfin.org/ZDB-GENE-030131-6395", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLSNPSAEQKGTEQAPASAAGPCHPAPHSPLYQEQLAIGCKETHREEFESGDKPQSSDFGKEGKLRDPRWTSPLSPSAGPSGEQLGVLERFLVSHHNDMKRLLTDTFGPLAQRLEAMEKRMDQLCSQSSAHTRSLAQLHSKVGQLGRDISFGCPNTPSVSSACSFGSNGEVAKDNKDILSNVCLSRPQSLYRSLSCEPKKDPICSWTMSTPSRSSQSPTRKPEDLSCEGQKFNASGSLSCEILKTSPLRQTDNSLQGKYSPVSDFEDLEMEVDAEKDRVALLVDTVISSSDDNDSQGPSCKQEVLSSDAENEESSPVEEDTLINQRLHVQKPLKLPYVKILKLSPPKSNSDPLYFLSKPKNSATSGKTVTLGNSTKVKDEHIQQQSLSEISFSFPIKPLVAQSNHDEPKLSSDPFQNHSKKEGEIWDKFKINGSFHSTTTSLSTSDFDHVPMSQQGRNELTGTNAGASEEGTKLDRKAQRIDCQFSSTKDRPLKSPSQESDMSVQPYCELTLSNHLVKDVGERKSFGSLLTFQACTSSHLSAPRNGSSKSVLDRSTNKLLTQLSDTALRLVGSCTSNDLNRWTGYSRAGSKLKHFGGKKQHLSGFPTLKAGETLSFIEQGAEIFNHRQPILDDFILPLSPQLTGMLACPSNDLPVNLDKGSACCPSLSQLFRPTTPPLSALSKWSFSGAGVSTVLALSSPTSFRKWFRHRRLNFPLTQLSHSGIHMVVSQILGRCRCHPFRPLVDFTAPPGIDNDHHYTRRSSQEVTRNRKRASARKAVCLLSKIHLTPERILDHPSRHSISPKSARLDVSSTESVPTFAIVSANVKYPGLHNRGVSREMNQVELYEANAEAQGGQRSKRVSQIRIRKTVPKPDNNLTPMGLPKPKRLKKKEFSLEEIYTNKNYKSPIPNRSLETIFEEPKEKNGSLVCIGHQKRKRVLDFPDFTQPRKRKAKTNLGPLRVKGPRGRPRRGRQDDADLDIMLIERLTELEDYFTSQGLEV", "length": 1000, "header": "tr|A0A8M9PLH6-1|A0A8M9PLH6_DANRE Isoform 1 of Uncharacterized protein wu:fi75a02 isoform X1 OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A0A8M9PLH6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH6/entry#A0A8M9PLH6-1", "sequence": { "sequence": "MLSNPSAEQKGTEQAPASAAGPCHPAPHSPLYQEQLAIGCKETHREEFESGDKPQSSDFGKEGKLRDPRWTSPLSPSAGPSGEQLGVLERFLVSHHNDMKRLLTDTFGPLAQRLEAMEKRMDQLCSQSSAHTRSLAQLHSKVGQLGRDISFGCPNTPSVSSACSFGSNGEVAKDNKDILSNVCLSRPQSLYRSLSCEPKKDPICSWTMSTPSRSSQSPTRKPEDLSCEGQKFNASGSLSCEILKTSPLRQTDNSLQGKYSPVSDFEDLEMEVDAEKDRVALLVDTVISSSDDNDSQGPSCKQEVLSSDAENEESSPVEEDTLINQRLHVQKPLKLPYVKILKLSPPKSNSDPLYFLSKPKNSATSGKTVTLGNSTKVKDEHIQQQSLSEISFSFPIKPLVAQSNHDEPKLSSDPFQNHSKKEGEIWDKFKINGSFHSTTTSLSTSDFDHVPMSQQGRNELTGTNAGASEEGTKLDRKAQRIDCQFSSTKDRPLKSPSQESDMSVQPYCELTLSNHLVKDVGERKSFGSLLTFQACTSSHLSAPRNGSSKSVLDRSTNKLLTQLSDTALRLVGSCTSNDLNRWTGYSRAGSKLKHFGGKKQHLSGFPTLKAGETLSFIEQGAEIFNHRQPILDDFILPLSPQLTGMLACPSNDLPVNLDKGSACCPSLSQLFRPTTPPLSALSKWSFSGAGVSTVLALSSPTSFRKWFRHRRLNFPLTQLSHSGIHMVVSQILGRCRCHPFRPLVDFTAPPGIDNDHHYTRRSSQEVTRNRKRASARKAVCLLSKIHLTPERILDHPSRHSISPKSARLDVSSTESVPTFAIVSANVKYPGLHNRGVSREMNQVELYEANAEAQGGQRSKRVSQIRIRKTVPKPDNNLTPMGLPKPKRLKKKEFSLEEIYTNKNYKSPIPNRSLETIFEEPKEKNGSLVCIGHQKRKRVLDFPDFTQPRKRKAKTNLGPLRVKGPRGRPRRGRQDDADLDIMLIERLTELEDYFTSQGLEV", "length": 1000, "header": "tr|A0A8M9PLH6-1|A0A8M9PLH6_DANRE Isoform 1 of Uncharacterized protein wu:fi75a02 isoform X1 OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A0A8M9PLH6-1" }, "locus": {} }, { "isoform_ac": "A0AB32TKG7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH6/entry#A0AB32TKG7-1", "sequence": { "sequence": "MLSNPSAEQKGTEQAPASAAGPCHPAPHSPLYQEQLAIGCKETHREEFESGDKPQSSDFGKEGKLRDPRWTSPLSPSAGPSGEQLGVLERFLVSHHNDMKRLLTDTFGPLAQRLEAMEKRMDQLCSQSSAHTRSLAQLHSKVGQLGRDISFGCPNTPSVSSACSFGSNGEVAKDNKDILSNVCLSRPQSLYRSLSCEPKKDPICSWTMSTPSRSSQSPTRKPEDLSCEGQKFNASGSLSCEILKTSPLRQTDNSLQGKYSPVSDFEDLEMEVDAEKDRVALLVDTVISSSDDNDSQGPSCKQEVLSSDAENEESSPVEEDTLINQRLHVQKPLKLPYVKILKLSPPKSNSDPLYFLSKPKNSATSGKTVTLGNSTKVKDEHIQQQSLSEISFSFPIKPLVAQSNHDEPKLSSDPFQNHSKKEGEIWDKFKINGSFHSTTTSLSTSDFDHVPMSQQGRNELTGTNAGASEEGTKLDRKAQRIDCQFSSTKDRPLKSPSQESDMSVQPYCELTLSNHLVKDVGERKSFGSLLTFQACTSSHLSAPRNGSSKSVLDRSTNKLLTQLSDTALRLVGSCTSNDLNRWTGYSRAGSKLKHFGGKKQHLSGFPTLKAGETLSFIEQGAEIFNHRQPILDDFILPLSPQLTGMLACPSNDLPVNLDKGSACCPSLSQLFRPTTPPLSALSKWSFSGAGVSTVLALSSPTSFRKWFRHRRLNFPLTQLSHSGIHMVVSQILGRCRCHPFRPLVDFTAPPGIDNDHQKAVCLLSKIHLTPERILDHPSRHSISPKSARLDVSSTESVPTFAIVSANVKYPGLHNRGVSREMNQVELYEANAEAQGGQRSKRVSQIRIRKTVPKPDNNLTPMGLPKPKRLKKKEFSLEEIYTNKNYKSPIPNRSLETIFEEPKEKNGSLVCIGHQKRKRVLDFPDFTQPRKRKAKTNLGPLRVKGPRGRPRRGRQDDADLDIMLIERLTELEDYFTSQGLEV", "length": 981, "header": "tr|A0AB32TKG7-1|A0A8M9PLH6_DANRE Computationally mapped isoform of Uncharacterized protein wu:fi75a02 isoform X1 OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A0A8M9PLH6-1" }, "locus": {} }, { "isoform_ac": "A0AC58JM78-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH6/entry#A0AC58JM78-1", "sequence": { "sequence": "MKRLLTDTFGPLAQRLEAMEKRMDQLCSQSSAHTRSLAQLHSKVGQLGRDISFGCPNTPSVSSACSFGSNGEVAKDNKDILSNVCLSRPQSLYRSLSCEPKKDPICSWTMSTPSRSSQSPTRKPEDLSCEGQKFNASGSLSCEILKTSPLRQTDNSLQGKYSPVSDFEDLEMEVDAEKDRVALLVDTVISSSDDNDSQGPSCKQEVLSSDAENEESSPVEEDTLINQRLHVQKPLKLPYVKILKLSPPKSNSDPLYFLSKPKNSATSGKTVTLGNSTKVKDEHIQQQSLSEISFSFPIKPLVAQSNHDEPKLSSDPFQNHSKKEGEIWDKFKINGSFHSTTTSLSTSDFDHVPMSQQGRNELTGTNAGASEEGTKLDRKAQRIDCQFSSTKDRPLKSPSQESDMSVQPYCELTLSNHLVKDVGERKSFGSLLTFQACTSSHLSAPRNGSSKSVLDRSTNKLLTQLSDTALRLVGSCTSNDLNRWTGYSRAGSKLKHFGGKKQHLSGFPTLKAGETLSFIEQGAEIFNHRQPILDDFILPLSPQLTGMLACPSNDLPVNLDKGSACCPSLSQLFRPTTPPLSALSKWSFSGAGVSTVLALSSPTSFRKWFRHRRLNFPLTQLSHSGIHMVVSQILGRCRCHPFRPLVDFTAPPGIDNDHQKAVCLLSKIHLTPERILDHPSRHSISPKSARLDVSSTESVPTFAIVSANVKYPGLHNRGVSREMNQVELYEANAEAQGGQRSKRVSQIRIRKTVPKPDNNLTPMGLPKPKRLKKKEFSLEEIYTNKNYKSPIPNRSLETIFEEPKEKNGSLVCIGHQKRKRVLDFPDFTQPRKRKAKTNLGPLRVKGPRGRPRRGRQDDADLDIMLIERLTELEDYFTSQGLEV", "length": 883, "header": "tr|A0AC58JM78-1|A0AC58JM78_DANRE Computationally mapped isoform of Uncharacterized protein wu:fi75a02 isoform X4 OS=Danio rerio OX=7955 GN=wu:fi75a02 PE=4 SV=1 CANONICAL=A0A8M9PLH6-1" }, "locus": {} }, { "isoform_ac": "A0AC58JM97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH6/entry#A0AC58JM97-1", "sequence": { "sequence": "MKRLLTDTFGPLAQRLEAMEKRMDQLCSQSSAHTRSLAQLHSKVGQLGRDISFGCPNTPSVSSACSFGSNGEVAKDNKDILSNVCLSRPQSLYRSLSCEPKKDPICSWTMSTPSRSSQSPTRKPEDLSCEGQKFNASGSLSCEILKTSPLRQTDNSLQGKYSPVSDFEDLEMEVDAEKDRVALLVDTVISSSDDNDSQGPSCKQEVLSSDAENEESSPVEEDTLINQRLHVQKPLKLPYVKILKLSPPKSNSDPLYFLSKPKNSATSGKTVTLGNSTKVKDEHIQQQSLSEISFSFPIKPLVAQSNHDEPKLSSDPFQNHSKKEGEIWDKFKINGSFHSTTTSLSTSDFDHVPMSQQGRNELTGTNAGASEEGTKLDRKAQRIDCQFSSTKDRPLKSPSQESDMSVQPYCELTLSNHLVKDVGERKSFGSLLTFQACTSSHLSAPRNGSSKSVLDRSTNKLLTQLSDTALRLVGSCTSNDLNRWTGYSRAGSKLKHFGGKKQHLSGFPTLKAGETLSFIEQGAEIFNHRQPILDDFILPLSPQLTGMLACPSNDLPVNLDKGSACCPSLSQLFRPTTPPLSALSKWSFSGAGVSTVLALSSPTSFRKWFRHRRLNFPLTQLSHSGIHMVVSQILGRCRCHPFRPLVDFTAPPGIDNDHHYTRRSSQEVTRNRKRASARKAVCLLSKIHLTPERILDHPSRHSISPKSARLDVSSTESVPTFAIVSANVKYPGLHNRGVSREMNQVELYEANAEAQGGQRSKRVSQIRIRKTVPKPDNNLTPMGLPKPKRLKKKEFSLEEIYTNKNYKSPIPNRSLETIFEEPKEKNGSLVCIGHQKRKRVLDFPDFTQPRKRKAKTNLGPLRVKGPRGRPRRGRQDDADLDIMLIERLTELEDYFTSQGLEV", "length": 902, "header": "tr|A0AC58JM97-1|A0AC58JM97_DANRE Computationally mapped isoform of Uncharacterized protein wu:fi75a02 isoform X3 OS=Danio rerio OX=7955 GN=wu:fi75a02 PE=4 SV=1 CANONICAL=A0A8M9PLH6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:569699", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569699", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q7C4-1", "protein_name": "Proline rich 14-like", "gene_name": "Prr14l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSSGVETQPVPLDSSMSAVVQELYSELSVSVSKELHAEQEPSKIADVKPGASRSPLSHGRASPLGLQRTHAEGCREESSETLDCRGKNGWCGLVDPTRDPMAYEILDREERPKSMEPKVFRDQGDQAQVFRDPCEGAKEDPCQHSTATKEKICPCQDLLPRQSSKGPVCADLPGEPQNNGGNVHNTTAALPELTEERQGTCTVSRMSKGKEESCDLDPVWEEADNHQQSLSHCKEKHSSAHNSSITKGSIDTVKPSEENSKILYLTSFLSGPKSLEKCGFECSGLIKACAEKTQKVDQMEDFTCGEERAVESSNHSNCHTEAGCPCTDSCTSMRNSSTEATEIMFKKTDVKITLNLHGNLINSEDHRKTVDVTHPEKRSEESSFSLLVHIEEPEQTTVKSSALNGKIYSKDATKSVVSIQRSLGDSLPSTALCNNFLFERKPPQSLMSEDPGSSEHNEISKPKKGTAKLPSSPGKPVQTSCDSISHFDEPITTCEMSKRSPNRALVAHKIEHECVSHQQVSLSSQDHVTTGSLSINREMPSATCRDVQESHHSLENGVNVTPDTQTIPAETKMEAMSPQGDRACGASSFIQTLNNKTRSSEGQKEMTAVHSTFFSSVRGAAASSFVTECQNVQSQDIFSCHCITRDASEKNMCSASAACELRKDSLKVSNCKIKCGNTSQDGNHCSQRPEGFVEKSTLLESEPAGREVQSSFLEGKVRSAVAAAVTHTASLNTATHMETGDEGLLGKKQDQRIDTEIYKHSTSACDTQELKQSANIPSPETLVDQSLSILSSHFKTMYQAAENLHQKADEVSDCQSNQNILDKCRCEGKPAGEGLNGDFGETDPEVSHRQKDLTVSSGSKVPLSCGGLKIKDPKRAFIDIPGSEEFTHSMLDVICPDCTDEPPEGVLGVEASSLSGHCTRQDTLAYHETIRSTSLLQGELNVECQGTELPNAAASSVDSSEIQKSHEEKVCNSLKDYEMEDCPDSAIDHEVKSVVDHEPNIRALDRAGVSLNSIHCEHQGKGGSMIEGLRLEANSEFGKRKTFGLSLKDSVSPGCQDSVKMVHSCLSSREHSPAGIFDEMPNSKHHFKPKDDEMLCENVKDCTVLSDMKAGIPMDLHNPSEGDSTYISVNKKVCKTCHSLKNSIDKHLPMTMETAIRMNKEETEKHQTGLLGHIPVGKASEETREGHGGNSQTHLKCQRVQNVTEAPQNQGPVDSALPKEACTYQKGTHALLGQHLSSGTVSDEVQDKQPVADQDESILIGAITLRKPSKDRIARQLQWLKYPKEESLCHSLKKDTELCTGTCLPGASWKEHDPSFAGGDRIHGAFVTLSHQHRLLSVKKQPHRTCKRISCQEPVTVRRKISKVRNSDCGKSFSNPIPTKAHRLLSPCTVPAKPLEPETVASENLRSHIPKPKATLCHSLRSRSCRKPTKESALLSKLSVLASRLTTATKPQELRCRRDSSSLVPLAKNYKRLRYKKLLDGFSHNAMQLDPYLAATGWNRGSNSRPLALYSLEAVKMSFIDLSNKMPSLLFGTENVPFSFHVKSVSSCMAESSRTFPEHCAPSRLALTEASQCSAPAPKWTFSFFLSHGCPGMATFREDTGLSSQTHTQAPLQEYGGTAIVQTRADRSGLGLHTLLALCSPGCYRIWTKRRNFSSNMPIMQRLFLTQFTQGLKGLRSPASIADKVFCSLPYSVGRVLSLWSQHGPSCTFKLPALHSTPSKQQGSLNALSSHTTIPNVPLPGMGAAHTTNSSHLRLEPVFPALVPKSCLVTEAAVSTLLLSASELAVPGCDELDGVSAACPRPQSSPAQQKEAEPEKRPKKVSQIRIRKTIPKPDPNLTPMGLPRPKRLKKKEFSLEEIYTNKNYKSPPASRCLETIFEEPKERNGTLISISQQKRKRVLEFQDFTVPRKRRARGKVKLAGSFTRAQKAALQTQELDALLIQKLMELETFFAKEGEQEHQPAAENSSGSPL", "length": 1971 }, "evidence": [ { "id": "RGD:1305469", "url": "https://alliancegenome.org/gene/RGD:1305469#orthology", "database": "AGR" }, { "id": "MGI:2443658", "url": "https://alliancegenome.org/gene/MGI:2443658#orthology", "database": "AGR" }, { "id": "HGNC:28738", "url": "https://alliancegenome.org/gene/HGNC:28738#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6395", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6395#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0RAJ5-1", "protein_name": "Proline rich 14-like", "gene_name": "Prr14l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSSGVETQPVPLGSSMSAVVQELYSGLSVSVSKELHAEQEPSMTPDLKPGASSSPISHGRASPQGLQRTHAEGCCEESSETVDYGGKTGWCGLVDPTRGPMAYEVLDREERPKSMEPKVFRDQGDQAQVFRGPCEGAKEDPCQHSTTTKEKICPSQDLLLIQSSKGPVCADCPGDARKNRGNVHNTAGTLPEATEERRGNSTVSKMSKGKEESCDLHPVCKEEDNHQPSLRHHKEKHSSAHDGSIAPGSIDAITPSEENSKILCLTPYLSGSKSLEKCGFESSGLTKASAEKTHKVDQSQDFTCREERTVESSNHSNCHTLAGCPRIDSCSSMLNSPTEATEITFKKNDVKITLNLDGNLINSEDHRKTVVDVTHPEENSEESSFSLLVYTEDPEQTTVKSSALNGKIYSKVAQSVVSLQRKLGDCPPNEALCNEFLPERKPLQSSMPEDPVSSECNEISKPKEGTAKLPSSPEKPVQPSQDSISHFDGPITVCEMSECSPNRELVAHKIEHECVSHQQVSLSSQDHVTADSLLSINREMPSAACKDVQESRRFLENGVNVTPDTQTIPAETKTEAMSPQGDKAYECASSFIQTLNIKTSSSEGQKEMTGVHSTLLSSVRGAAGSSLVRECQNVQSRDLFSCHCITQDASGKNMCSACAAYEPSKDILKVSNCKIKCGNASQRPEDFAENSTLLESEPAGREMQSSILGGTVRGSATAAVSHSAPLNAAALVETGDEGLVGRKQDQHRDTEIYKHSISACDTQELSQSVNIPSPETVVDQSLSVSSSHFKAMPRAAESLHQKAGEVSDCQSSQNSLDKCRCEGKPAREGLNGDYRETIPEVSHKQKDRIVCSGSKVPLSCGSLKQKDPKRAFKNIPGSEEFTHSMLDVVCPDCRGEPTEGAQGLEASSLSGHCTRHESLAHHETLRSTLSLRGELNVVFIGTPGWHSELPNAAASTVDSPEMEESHEEKVCKSLKDYEVEECPDSAIEHEVKSIEDHEPHRRAPDREGVSLNDIHCEHQGKGGSMTEGLRLETKAEFGKKKTFGLSLKDSVSPGCQDSIKVVHSCLSSLEHSPADVPGEMPNLKHHFKPKDGKVLCENVKDCTVLSDMKEGIPMDSNNPCERDSTYVSVDRNACKACHSHRNSTGKHLPLTMETAIKMNKEETEEHQKGLLGHIAVGEAAEETITRAGHDGNSQTHVKCQRMQNVAESPQNQGVVDSALPKEECAHQKGTQALPEQHTSANLLSDEMQSKKQPVADQDESLMEEVTLRKPTKDEIARQLQRLKSPKEESLCPSLKKDTQLYTGTCLPGTSWKEGDPTFAGGDRIHGAFVTLSYPQRLLPVKKQPHRTCKRISCQEPVTVRRKISKVRNSDCGKSFSNPVPTKAHRLLSPCTVPAKPLEPETVALESLRGHTPKPKATLCHSLRSLSCRKPTKESALLDKLSVLASKLTLAAKPQKLRCRRYSSSLVPLAKNYKRLRYKKLLDGFSHNAVQLDPYLAATGWSRGSHSRPLALYSLEAVKISFIDLSNKMPSLLLGTENAPFSFHVKSASSCMAESSRTFPEHCAPSRLALTEASQCSPPSPKWTFSFFLSHGCPGVATFREDTGLSSQTHTQAPLQDYGGTAIVQTRADCSGLGLHTLLALCSPGCYRIWTKRRNFSSHMPTMQRLLLTQFTQGLKGLRSPASIADRVFSSLPYSVGRVLSIWSQHGPSCTFKLPALHSPHSKQQGSLSALSSHTTIPHVPLPGMEAAHNTNSSHLRLEPVFPALVPKSCLVTEPSVSTLLLSASELQVPAFDELDGVSAACPRPQSSPAQQEEAEPEKRPKKVSQIRIRKTIPKPDPNLTPMGLPRPKRLKKKEFSLEEIYTNKNYKSPPASRCLETIFEEPKERNGTLISISQQKRKRVLEFPDFTVPRKRRARGKVKLAGSFTRAQKAALQTRELDALLIQKLMDLETFFAKEEEQEHQPAAENSSGSLL", "length": 1973 }, "evidence": [ { "id": "RGD:1305469", "url": "https://alliancegenome.org/gene/RGD:1305469#orthology", "database": "AGR" }, { "id": "MGI:2443658", "url": "https://alliancegenome.org/gene/MGI:2443658#orthology", "database": "AGR" }, { "id": "HGNC:28738", "url": "https://alliancegenome.org/gene/HGNC:28738#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6395", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6395#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5THK1-1", "protein_name": "Protein PRR14L", "gene_name": "PRR14L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSSGVETQPVPLDSSMSAVVQELYSELPVSVSRELHADPEPSVIPDVKPGASSSLLSQNRALPLELQRTHVESCCEETYETLDHGSEPGRCGLVDSTAGGSVASGILDRAKRSESMEPKVFRDPGGQAGIIREPSEGAKEDPHQHSTAAEEKTSPSQEDLLMQSSKELSHVDLPEDFLRSKEGNVQITAETLLKSAEVQGMKVNGTKTDNNEGHKNGNVSKDLSAGCGEFQEVDKIMTSDEVSETSTLVTPEPLTFVDPVLTEATPKEKECEELKSCPWLSLPGNSAISNVDNGKEELCKPNLVCEADDNHQQLHGHHNEQPSSTHDSPTATSPLKENSEVSCFTSDLSGPESRTISLENCGFEGGGLLKRSAEKTDSSYFYRGDDQGKNLASREENEERLLIPRSERGGPFLFNAREPEKEISGRCSGEKEPVVSPKENIHNNCIQDSLHTGNSSSLMPNSFTEATEVMLNKNDLKITVHVQGNLTNPEDHKETFTNMSHPGGHSEESSFSSLMQIEEAGQTTPVEPNILSKSFYTKDCNSLVSIQRNLEGNTQLNEASCNDFLFERKSIVSLMPEDQISPVSEVLKPKQGTALLLPSPEFDYRPESEKVIQTSHDDIPLLDEQSIACEMNELSCTNELVVNKVESECVLNQQVSLNSQEHANLPTDSLLHLNKEMPLATGRDAHQSHHPPLEGRADVIADIQTIPIQTKIKDISPPGNQTCGASSNCPTLNIKPVSLERKKEMADSGTKALHSRLRSNKREAAGFPQVVSVIECHSVQSQDISSCHRVRKNVSQENMCSASAAFKSSKISLQVDNSLITKYENAFQHRDHCCQGTGHSVEKSSCKVSYTSQERELDGKETNGSLPGDKIRNKMVAGLLNSGISNKTIHTSSSIKLSEEGLEGKEQDVSKETVFCKYNISDHAIQELNQTVNIPGPEKVLDQSPTVMFSSFKNVKSVETLDQKADEVLDCQSNQNRPDECKSEGQSAKEMLSSDQRETVTEPHGEVNHNQKDLLVSSGSNNSLPCGSPKKCNLKGAFVKMSGCDESTEGMVDIVYTDCSNKLAEGVLDVKASNLLDCGARQEKLAFQEDSRSTLSRRELDAAHTGTTGQDSDFPVTAASTVDFLKIKKSCEENVCRSLKDCEMEKCPDSCAHEMESVADHEPNKRILGRVNLSLNDSHYGQQDKGTSLRETQEMTEGSRLEPNSEFGKESTFGISSKESMSCHDESSVSLRSLKSIEIMPSQENSETNVNSEETDLKNLCKPKDGEMLCENVKDCTVLPEMKEIVSRDWSNSSDRDSVCTCVEKNACKACHPHENSSDRHLPLTVKTDIKVKGEETEEHQRGRLGYLTVGEQSEELVTRETGDGDPVSNISQTHFKCRGILNHAEKQQSPEVLDYMLQKEEKYIRQQKAHTISQQCISSSLLLDDAQNQNQPKADKDESTMINEITLAKLAKDSIVAQTQKLEDQKEERLHHPLRKDTESCTSPCLLGAPRKAQDPSSAGCDQIHGAFAKKGVLPLKKQPHRTCKKVSYQEQIIVGRKIGKIRSSAFLKSSSNPIPTKAHRLLSLCTLSAPTRLEPETAPTKSLVSHIPKQMSTPCHPLRSLNFRKTTKESALLNKLSILASKLAPAMKTQKLRYRRCSSELLPMAKSYKRLRYKRLLDGFSSSTEQLNPYLAASGWDKRPNSKPMALYSLESIKMTFIDLSNKMPSLLFGSEIFPVSFHVKSSSSDCTTESSRTFPEHCAPARLALGEALQCPSQPPKWTFSFFLSHGCPGMATFREDTGVHSQTHTQAPPQPPAPLQDYGGTAIVQTRADCSVLGLHTLLALCSPGCYRIWTKKRSFSSHMPTMQRLFMTQFTQGLKGLRSPASIADKVFCSLPYSVGRVLSIWSQHGPSVCSFEISSLHSPHCKRQPSLGTTSSHTMLPYVPLPGMEATYNTSGSQTRLEPPFPALVPKSCLVAESAVSKLLLSASEFQVRGLDELDGVKAACPCPQSSPPEQKEAEPEKRPKKVSQIRIRKTIPRPDPNLTPMGLPRPKRLKKKEFSLEEIYTNKNYKSPPANRCLETIFEEPKERNGTLISISQQKRKRVLEFQDFTVPRKRRARGKVKVAGSFTRAQKAAVQSRELDALLIQKLMELETFFAKEEEQEQSSGC", "length": 2151 }, "evidence": [ { "id": "RGD:1305469", "url": "https://alliancegenome.org/gene/RGD:1305469#orthology", "database": "AGR" }, { "id": "MGI:2443658", "url": "https://alliancegenome.org/gene/MGI:2443658#orthology", "database": "AGR" }, { "id": "HGNC:28738", "url": "https://alliancegenome.org/gene/HGNC:28738#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6395", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6395#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 545, "end_pos": 547, "annotation": "n_glycosylation_sequon" }, { "start_pos": 876, "end_pos": 878, "annotation": "n_glycosylation_sequon" }, { "start_pos": 910, "end_pos": 912, "annotation": "n_glycosylation_sequon" }, { "start_pos": 924, "end_pos": 926, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PLH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH6" }, { "id": "PF15386", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15386" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tantalus-like", "eco_id": "ECO_0000259", "start_pos": 877, "end_pos": 934, "start_aa": "Leu", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 417, "end_pos": 419 }, { "start_pos": 432, "end_pos": 434 }, { "start_pos": 545, "end_pos": 547 }, { "start_pos": 876, "end_pos": 878 }, { "start_pos": 910, "end_pos": 912 }, { "start_pos": 924, "end_pos": 926 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PMK7-1", "uniprot_ac": "A0A8M9PMK7", "uniprot_id": "A0A8M9PMK7_DANRE", "mass": { "chemical_mass": 237816.0, "monoisotopic_mass": 237816.0 }, "refseq": { "ac": "XP_021332717", "name": "dedicator of cytokinesis protein 9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332717" }, "gene_names": [ { "name": "dock9b", "type": "recommended", "evidence": [ { "id": "A0A8M9PMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7" } ] }, { "name": "dock9b", "type": "synonym", "evidence": [ { "id": "XP_021332717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332717" } ] } ], "protein_names": [ { "name": "Dedicator of cytokinesis protein 9 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#names_and_taxonomy" } ] }, { "name": "dedicator of cytokinesis protein 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021332717", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332717" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021332717.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021332717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332717" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMK7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dock9b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090916-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090916-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PMK7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PMK7", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000016311", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000016311", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08697", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08697", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11698", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11698", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13267", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13267", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100151488", "url": "https://www.ncbi.nlm.nih.gov/gene/100151488", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026791", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026791", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027357", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027357", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037809", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037809", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046769", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046769", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046773", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046773", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR23317", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23317", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23317:SF77", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23317:SF77", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06920", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06920", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF11878", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11878", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14429", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14429", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20421", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20421", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20422", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20422", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF28208", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28208", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021332717", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332717", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PMK7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PMK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AA54CSK6", "url": "https://www.uniprot.org/uniprotkb/A0AA54CSK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AA54CSK6-1", "url": "https://www.uniprot.org/uniprotkb/A0AA54CSK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TQA1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQA1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TQA1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQA1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TQC1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TQC1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TW96", "url": "https://www.uniprot.org/uniprotkb/A0AB32TW96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TW96-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TW96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TX62", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX62", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TX62-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX62-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTP9", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTP9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTQ1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTQ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTQ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTQ8", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTQ9", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTR1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTR1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTR1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTR1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTR3", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTR3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTR3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTR3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTR4", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTR4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTR5", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTR5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTR8", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTR8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090916-2", "url": "https://zfin.org/ZDB-GENE-090916-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGCTASVILFEGLRRMIYRNCGYVCKPELQAAEPDEDEDTLSRRESLAVTPLAAASAVKPKVIEPLDYENVLVQRKTQILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSVPDGAEKRASSLLVQECIKTYNSDWHVVNYKYEDYSGDFRQLPNKVPRPEKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWLYKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRRFAFELKMQDKSTYLLAADSEGEMDDWISTLNKILHSSFELAMQERRNGELHDDDEMGKTDISPGNFQDSFQSARDIESKMRSETRLKLFTLDPDTQRLDLSGIEPDVKQFEEKFGKRVLVCCNDLSFNLQSCVAENEEGPTTNVEPFFVVLSLFDVQNSRKISADFHVDLNHPLVRSLIPSPSMQINGGVDTPHGETLLSELQGMLHYPKKGVFSVTCPHPDIFLVARIEKVLQGGITHCAEPYMKSSDSSKVAQKVLKNAKMACSRLGQYRMPFAWAARPVFKDASGTLDKSARFSALYRQDSNKLSEEDLFKLLADFRKPEKMAKLPVILGNLDVTIDNVPPDMANCVTPSYIPVRPFESNGPNDGVLLEVEEFVPCIAKCSQPFTTYNNHLYVYPKHLKYDNQKSFAKARNIAVCVEFRESDEEDAQALKCIYGRPGGPVFTKHAYAAVLHHQQNPEFYDEIKIELPTQLHEKHHLLFTFYHISCDSSTKKRDIVETPVGSAWLPLLKDGRVVMSEQHISVASNLPNGYLSCQEGVSKHSSPEIKWVDGGRPLFRVSTHLVSTIYTQDQHLHNFFHHFHSMQSGAPRPTEGELVKYLKSLHAMEGHVMINFLPTILNQMIHVLTSATNEDVAVNTTRVMVHIVAQCHEEGLEHYLRSYVKYVFKTESYSNGNSKTVHEELAKAMTSILKPSTDFLTSNKLLKYSWYFFEALVKSMAQYLMESGKVKLSRNQRFTASFHHAVETLVNMLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNVRDASNFNTNQNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARSQDGVGFMVPDRKSLTLPVSRNRGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 2093, "header": "tr|A0A8M9PMK7-1|A0A8M9PMK7_DANRE Isoform 1 of Dedicator of cytokinesis protein 9 isoform X1 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=2 CANONICAL=A0A8M9PMK7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PMK7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0A8M9PMK7-1", "sequence": { "sequence": "MGCTASVILFEGLRRMIYRNCGYVCKPELQAAEPDEDEDTLSRRESLAVTPLAAASAVKPKVIEPLDYENVLVQRKTQILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSVPDGAEKRASSLLVQECIKTYNSDWHVVNYKYEDYSGDFRQLPNKVPRPEKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWLYKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRRFAFELKMQDKSTYLLAADSEGEMDDWISTLNKILHSSFELAMQERRNGELHDDDEMGKTDISPGNFQDSFQSARDIESKMRSETRLKLFTLDPDTQRLDLSGIEPDVKQFEEKFGKRVLVCCNDLSFNLQSCVAENEEGPTTNVEPFFVVLSLFDVQNSRKISADFHVDLNHPLVRSLIPSPSMQINGGVDTPHGETLLSELQGMLHYPKKGVFSVTCPHPDIFLVARIEKVLQGGITHCAEPYMKSSDSSKVAQKVLKNAKMACSRLGQYRMPFAWAARPVFKDASGTLDKSARFSALYRQDSNKLSEEDLFKLLADFRKPEKMAKLPVILGNLDVTIDNVPPDMANCVTPSYIPVRPFESNGPNDGVLLEVEEFVPCIAKCSQPFTTYNNHLYVYPKHLKYDNQKSFAKARNIAVCVEFRESDEEDAQALKCIYGRPGGPVFTKHAYAAVLHHQQNPEFYDEIKIELPTQLHEKHHLLFTFYHISCDSSTKKRDIVETPVGSAWLPLLKDGRVVMSEQHISVASNLPNGYLSCQEGVSKHSSPEIKWVDGGRPLFRVSTHLVSTIYTQDQHLHNFFHHFHSMQSGAPRPTEGELVKYLKSLHAMEGHVMINFLPTILNQMIHVLTSATNEDVAVNTTRVMVHIVAQCHEEGLEHYLRSYVKYVFKTESYSNGNSKTVHEELAKAMTSILKPSTDFLTSNKLLKYSWYFFEALVKSMAQYLMESGKVKLSRNQRFTASFHHAVETLVNMLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNVRDASNFNTNQNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARSQDGVGFMVPDRKSLTLPVSRNRGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 2093, "header": "tr|A0A8M9PMK7-1|A0A8M9PMK7_DANRE Isoform 1 of Dedicator of cytokinesis protein 9 isoform X1 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=2 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AA54CSK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AA54CSK6-1", "sequence": { "sequence": "MASSAQPETRKFTRGLSKPGTAAELRQSVSEVVRTSVLVVKPKVIEPLDYENVLVQRKTQILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSVPDGAEKRASSLLVQECIKTYNSDWHVVNYKYEDYSGDFRQLPNKVPRPEKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWLYKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRRFAFELKMQDKSTYLLAADSEGEMDDWISTLNKILHSSFELAMQERRNGELHDDDEMGKTDISPGNFQDSFQSARDIESKMRSETRLKLFTLDPDTQRLDLSGIEPDVKQFEEKFGKRVLVCCNDLSFNLQSCVAENEEGPTTNVEPFFVVLSLFDVQNSRKISADFHVDLNHPLVRSLIPSPSMQINGGVDTPHGETLLSELQGMLHYPKKGVFSVTCPHPDIFLVARIEKVLQGGITHCAEPYMKSSDSSKVAQKVLKNAKMACSRLGQYRMPFAWAARPVFKDASGTLDKSARFSALYRQDSNKLSEEDLFKLLADFRKPEKMAKLPVILGNLDVTIDNVPPDMANCVTPSYIPVRPFESNGPNDGVLLEVEEFVPCIAKCSQPFTTYNNHLYVYPKHLKYDNQKSFAKARNIAVCVEFRESDEEDAQALKCIYGRPGGPVFTKHAYAAVLHHQQNPEFYDEIKIELPTQLHEKHHLLFTFYHISCDSSTKKRDIVETPVGSAWLPLLKDGRVVMSEQHISVASNLPNGYLSCQEGVSKHSSPEIKWVDGGRPLFRVSTHLVSTIYTQDQHLHNFFHHFHSMQSGAPRPTEGELVKYLKSLHAMEGHVMINFLPTILNQMIHVLTSATNEDVAVNTTRVMVHIVAQCHEEGLEHYLRSYVKYVFKTESYSNGNSKTVHEELAKAMTSILKPSTDFLTSNKLLKYSWYFFEALVKSMAQYLMESGKVKLSRNQRFTASFHHAVETLVNMLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNVRDASNFNTNQNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARSQDGVGFMVPDRKSLTLPVSRNRGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 2075, "header": "tr|A0AA54CSK6-1|A0AA54CSK6_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X3 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=1 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AB32TQA1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AB32TQA1-1", "sequence": { "sequence": "MASSAQPETRKFTRGLSKPGTAAELRQSVSEVVRTSVLVVKPKVIEPLDYENVLVQRKTQILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSVPDGAEKRASSLLVQECIKTYNSDWHVVNYKYEDYSGDFRQLPNKVPRPEKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWLYKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRRFAFELKMQDKSTYLLAADSEGEMDDWISTLNKILHSSFELAMQERRNGELHDDDEMGKTDISPGNFQDSFQSARDIESKMRSETRLKLFTLDPDTQRLDLSGIEPDVKQFEEKFGKRVLVCCNDLSFNLQSCVAENEEGPTTNVEPFFVVLSLFDVQNSRKISADFHVDLNHPLVRSLIPSPSMQINGGVDTPHGETLLSELQGMLHYPKKGVFSVTCPHPDIFLVARIEKVLQGGITHCAEPYMKSSDSSKVAQKVLKNAKMACSRLGQYRMPFAWAARPVFKDASGTLDKSARFSALYRQDSNKLSEEDLFKLLADFRKPEKMAKLPVILGNLDVTIDNVPPDMANCVTPSYIPVRPFESNGPNDGVLLEVEEFVPCIAKCSQPFTTYNNHLYVYPKHLKYDNQKSFAKARNIAVCVEFRESDEEDAQALKCIYGRPGGPVFTKHAYAAVLHHQQNPEFYDEIKIELPTQLHEKHHLLFTFYHISCDSSTKKRDIVETPVGSAWLPLLKDGRVVMSEQHISVASNLPNGYLSCQEGVSKHSSPEIKWVDGGRPLFRVSTHLVSTIYTQDQHLHNFFHHFHSMQSGAPRPTEGELVKYLKSLHAMEGHVMINFLPTILNQMIHVLTSATNEDVAVNTTRVMVHIVAQCHEEGLEHYLRSYVKYVFKTESYSNGNSKTVHEELAKAMTSILKPSTDFLTSNKLLKYSWYFFEALVKSMAQYLMESGKVKLSRNQRFTASFHHAVETLVNMLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNVRDASNFNTNQNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 2052, "header": "tr|A0AB32TQA1-1|A0A8M9PMK7_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X1 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=2 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AB32TQC1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AB32TQC1-1", "sequence": { "sequence": "MGCTASVILFEGLRRMIYRNCGYVCKPELQAAEPDEDEDTLSRRESLAVTPLAAASAVKPKVIEPLDYENVLVQRKTQILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSVPDGAEKRASSLLVQECIKTYNSDWHVVNYKYEDYSGDFRQLPNKVPRPEKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWLYKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRRFAFELKMQDKSTYLLAADSEGEMDDWISTLNKILHSSFELAMQERRNGELHDDDEMGKTDISPGNFQDSFQSARDIESKMRSETRLKLFTLDPDTQRLDLSGIEPDVKQFEEKFGKRVLVCCNDLSFNLQSCVAENEEGPTTNVEPFFVVLSLFDVQNSRKISADFHVDLNHPLVRSLIPSPSMQINGGVDTPHGETLLSELQGMLHYPKKGVFSVTCPHPDIFLVARIEKVLQGGITHCAEPYMKSSDSSKVAQKVLKNAKMACSRLGQYRMPFAWAARPVFKDASGTLDKSARFSALYRQDSNKLSEEDLFKLLADFRKPEKMAKLPVILGNLDVTIDNVPPDMANCVTPSYIPVRPFESNGPNDGVLLEVEEFVPCIAKCSQPFTTYNNHLYVYPKHLKYDNQKSFAKARNIAVCVEFRESDEEDAQALKCIYGRPGGPVFTKHAYAAVLHHQQNPEFYDEIKIELPTQLHEKHHLLFTFYHISCDSSTKKRDIVETPVGSAWLPLLKDGRVVMSEQHISVASNLPNGYLSCQEGVSKHSSPEIKWVDGGRPLFRVSTHLVSTIYTQDQHLHNFFHHFHSMQSGAPRPTEGELVKYLKSLHAMEGHVMINFLPTILNQMIHVLTSATNEDVAVNTTRVMVHIVAQCHEEGLEHYLRSYVKYVFKTESYSNGNSKTVHEELAKAMTSILKPSTDFLTSNKLLKYSWYFFEALVKSMAQYLMESGKVKLSRNQRFTASFHHAVETLVNMLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNVRDASNFNTNQNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 2070, "header": "tr|A0AB32TQC1-1|A0A8M9PMK7_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X1 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=2 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AB32TW96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AB32TW96-1", "sequence": { "sequence": "MGCTASVILFEGLRRMIYRNCGYVCKPELQAAEPDEDEDTLSRRESLAVTPLAAASAVKPKVIEPLDYENVLVQRKTQILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSVPDGAEKRASSLLVQECIKTYNSDWHVVNYKYEDYSGDFRQLPNKVPRPEKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWLYKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRRFAFELKMQDKSTYLLAADSEGEMDDWISTLNKILHSSFELAMQERRNGELHDDDEMGKTDISPGNFQDSFQSARDIESKMRSETRLKLFTLDPDTQRLDLSGIEPDVKQFEEKFGKRVLVCCNDLSFNLQSCVAENEEGPTTNVEPFFVVLSLFDVQNSRKISADFHVDLNHPLVRSLIPSPSMQINGGVDTPHGETLLSELQGMLHYPKKGVFSVTCPHPDIFLVARIEKVLQGGITHCAEPYMKSSDSSKVAQKVLKNAKMACSRLGQYRMPFAWAARPVFKDASGTLDKSARFSALYRQDSNKLSEEDLFKLLADFRKPEKMAKLPVILGNLDVTIDNVPPDMANCVTPSYIPVRPFESNGPNDGVLLEVEEFVPCIAKCSQPFTTYNNHLYVYPKHLKYDNQKSFAKARNIAVCVEFRESDEEDAQALKCIYGRPGGPVFTKHAYAAVLHHQQNPEFYDEIKIELPTQLHEKHHLLFTFYHISCDSSTKKRDIVETPVGSAWLPLLKDGRVVMSEQHISVASNLPNGYLSCQEGVSKHSSPEIKWVDGGRPLFRVSTHLVSTIYTQDQHLHNFFHHFHSMQSGAPRPTEGELVKYLKSLHAMEGHVMINFLPTILNQMIHVLTSATNEDVAVNTTRVMVHIVAQCHEEGLEHYLRSYVKYVFKTESYSNGNSKTVHEELAKAMTSILKPSTDFLTSNKLLKYSWYFFEALVKSMAQYLMESGKVKLSRNQRFTASFHHAVETLVNMLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARSQDGVGFMVPDRKSLTLPVSRNRGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 2082, "header": "tr|A0AB32TW96-1|A0A8M9PMK7_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X1 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=2 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AB32TX62-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AB32TX62-1", "sequence": { "sequence": "MQGKAGRAARKDAVCETPQQGRTLGEMEVDGDTAMPVGVKPKVIEPLDYENVLVQRKTQILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSVPDGAEKRASSLLVQECIKTYNSDWHVVNYKYEDYSGDFRQLPNKVPRPEKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWLYKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRRFAFELKMQDKSTYLLAADSEGEMDDWISTLNKILHSSFELAMQERRNGELHDDDEMGKTDISPGNFQDSFQSARDIESKMRSETRLKLFTLDPDTQRLDLSGIEPDVKQFEEKFGKRVLVCCNDLSFNLQSCVAENEEGPTTNVEPFFVVLSLFDVQNSRKISADFHVDLNHPLVRSLIPSPSMQINGGVDTPHGETLLSELQGMLHYPKKGVFSVTCPHPDIFLVARIEKVLQGGITHCAEPYMKSSDSSKVAQKVLKNAKMACSRLGQYRMPFAWAARPVFKDASGTLDKSARFSALYRQDSNKLSEEDLFKLLADFRKPEKMAKLPVILGNLDVTIDNVPPDMANCVTPSYIPVRPFESNGPNDGVLLEVEEFVPCIAKCSQPFTTYNNHLYVYPKHLKYDNQKSFAKARNIAVCVEFRESDEEDAQALKCIYGRPGGPVFTKHAYAAVLHHQQNPEFYDEIKIELPTQLHEKHHLLFTFYHISCDSSTKKRDIVETPVGSAWLPLLKDGRVVMSEQHISVASNLPNGYLSCQEGVSKHSSPEIKWVDGGRPLFRVSTHLVSTIYTQDQHLHNFFHHFHSMQSGAPRPTEGELVKYLKSLHAMEGHVMINFLPTILNQMIHVLTSATNEDVAVNTTRVMVHIVAQCHEEGLEHYLRSYVKYVFKTESYSNGNSKTVHEELAKAMTSILKPSTDFLTSNKLLKYSWYFFEALVKSMAQYLMESGKVKLSRNQRFTASFHHAVETLVNMLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNVRDASNFNTNQNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARSQDGVGFMVPDRKSLTLPVSRNRGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 2074, "header": "tr|A0AB32TX62-1|A0A8M9PMK7_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X1 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=2 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JTP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AC58JTP9-1", "sequence": { "sequence": "MLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNVRDASNFNTNQNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARSQDGVGFMVPDRKSLTLPVSRNRGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 1084, "header": "tr|A0AC58JTP9-1|A0AC58JTP9_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X12 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=1 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JTQ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AC58JTQ1-1", "sequence": { "sequence": "MASSAQPETRKFTRGLSKPGTAAELRQSVSEVVRTSVLVVKPKVIEPLDYENVLVQRKTQILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSVPDGAEKRASSLLVQECIKTYNSDWHVVNYKYEDYSGDFRQLPNKVPRPEKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWLYKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRRFAFELKMQDKSTYLLAADSEGEMDDWISTLNKILHSSFELAMQERRNGELHDDDEMGKTDISPGNFQDSFQSARDIESKMRSETRLKLFTLDPDTQRLDLSGIEPDVKQFEEKFGKRVLVCCNDLSFNLQSCVAENEEGPTTNVEPFFVVLSLFDVQNSRKISADFHVDLNHPLVRSLIPSPSMQINGGVDTPHGETLLSELQGMLHYPKKGVFSVTCPHPDIFLVARIEKVLQGGITHCAEPYMKSSDSSKVAQKVLKNAKMACSRLGQYRMPFAWAARPVFKDASGTLDKSARFSALYRQDSNKLSEEDLFKLLADFRKPEKMAKLPVILGNLDVTIDNVPPDMANCVTPSYIPVRPFESNGPNDGVLLEVEEFVPCIAKCSQPFTTYNNHLYVYPKHLKYDNQKSFAKARNIAVCVEFRESDEEDAQALKCIYGRPGGPVFTKHAYAAVLHHQQNPEFYDEIKIELPTQLHEKHHLLFTFYHISCDSSTKKRDIVETPVGSAWLPLLKDGRVVMSEQHISVASNLPNGYLSCQEGVSKHSSPEIKWVDGGRPLFRVSTHLVSTIYTQDQHLHNFFHHFHSMQSGAPRPTEGELVKYLKSLHAMEGHVMINFLPTILNQMIHVLTSATNEDVAVNTTRVMVHIVAQCHEEGLEHYLRSYVKYVFKTESYSNGNSKTVHEELAKAMTSILKPSTDFLTSNKLLKYSWYFFEALVKSMAQYLMESGKVKLSRNQRFTASFHHAVETLVNMLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARSQDGVGFMVPDRKSLTLPVSRNRGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 2064, "header": "tr|A0AC58JTQ1-1|A0AC58JTQ1_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X6 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=1 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JTQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AC58JTQ8-1", "sequence": { "sequence": "MASSAQPETRKFTRGLSKPGTAAELRQSVSEVVRTSVLVVKPKVIEPLDYENVLVQRKTQILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSVPDGAEKRASSLLVQECIKTYNSDWHVVNYKYEDYSGDFRQLPNKVPRPEKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWLYKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRRFAFELKMQDKSTYLLAADSEGEMDDWISTLNKILHSSFELAMQERRNGELHDDDEMGKTDISPGNFQDSFQSARDIESKMRSETRLKLFTLDPDTQRLDLSGIEPDVKQFEEKFGKRVLVCCNDLSFNLQSCVAENEEGPTTNVEPFFVVLSLFDVQNSRKISADFHVDLNHPLVRSLIPSPSMQINGGVDTPHGETLLSELQGMLHYPKKGVFSVTCPHPDIFLVARIEKVLQGGITHCAEPYMKSSDSSKVAQKVLKNAKMACSRLGQYRMPFAWAARPVFKDASGTLDKSARFSALYRQDSNKLSEEDLFKLLADFRKPEKMAKLPVILGNLDVTIDNVPPDMANCVTPSYIPVRPFESNGPNDGVLLEVEEFVPCIAKCSQPFTTYNNHLYVYPKHLKYDNQKSFAKARNIAVCVEFRESDEEDAQALKCIYGRPGGPVFTKHAYAAVLHHQQNPEFYDEIKIELPTQLHEKHHLLFTFYHISCDSSTKKRDIVETPVGSAWLPLLKDGRVVMSEQHISVASNLPNGYLSCQEGVSKHSSPEIKWVDGGRPLFRVSTHLVSTIYTQDQHLHNFFHHFHSMQSGAPRPTEGELVKYLKSLHAMEGHVMINFLPTILNQMIHVLTSATNEDVAVNTTRVMVHIVAQCHEEGLEHYLRSYVKYVFKTESYSNGNSKTVHEELAKAMTSILKPSTDFLTSNKLLKYSWYFFEALVKSMAQYLMESGKVKLSRNQRFTASFHHAVETLVNMLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 2041, "header": "tr|A0AC58JTQ8-1|A0AC58JTQ8_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X11 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=1 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JTQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AC58JTQ9-1", "sequence": { "sequence": "MGCTASVILFEGLRRMIYRNCGYVCKPELQAAEPDEDEDTLSRRESLAVTPLAAASAVKPKVIEPLDYENVLVQRKTQILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSVPDGAEKRASSLLVQECIKTYNSDWHVVNYKYEDYSGDFRQLPNKVPRPEKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWLYKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRRFAFELKMQDKSTYLLAADSEGEMDDWISTLNKILHSSFELAMQERRNGELHDDDEMGKTDISPGNFQDSFQSARDIESKMRSETRLKLFTLDPDTQRLDLSGIEPDVKQFEEKFGKRVLVCCNDLSFNLQSCVAENEEGPTTNVEPFFVVLSLFDVQNSRKISADFHVDLNHPLVRSLIPSPSMQINGGVDTPHGETLLSELQGMLHYPKKGVFSVTCPHPDIFLVARIEKVLQGGITHCAEPYMKSSDSSKVAQKVLKNAKMACSRLGQYRMPFAWAARPVFKDASGTLDKSARFSALYRQDSNKLSEEDLFKLLADFRKPEKMAKLPVILGNLDVTIDNVPPDMANCVTPSYIPVRPFESNGPNDGVLLEVEEFVPCIAKCSQPFTTYNNHLYVYPKHLKYDNQKSFAKARNIAVCVEFRESDEEDAQALKCIYGRPGGPVFTKHAYAAVLHHQQNPEFYDEIKIELPTQLHEKHHLLFTFYHISCDSSTKKRDIVETPVGSAWLPLLKDGRVVMSEQHISVASNLPNGYLSCQEGVSKHSSPEIKWVDGGRPLFRVSTHLVSTIYTQDQHLHNFFHHFHSMQSGAPRPTEGELVKYLKSLHAMEGHVMINFLPTILNQMIHVLTSATNEDVAVNTTRVMVHIVAQCHEEGLEHYLRSYVKYVFKTESYSNGNSKTVHEELAKAMTSILKPSTDFLTSNKLLKYSWYFFEALVKSMAQYLMESGKVKLSRNQRFTASFHHAVETLVNMLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 2059, "header": "tr|A0AC58JTQ9-1|A0AC58JTQ9_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X8 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=1 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JTR1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AC58JTR1-1", "sequence": { "sequence": "MQGKAGRAARKDAVCETPQQGRTLGEMEVDGDTAMPVGVKPKVIEPLDYENVLVQRKTQILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSVPDGAEKRASSLLVQECIKTYNSDWHVVNYKYEDYSGDFRQLPNKVPRPEKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWLYKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRRFAFELKMQDKSTYLLAADSEGEMDDWISTLNKILHSSFELAMQERRNGELHDDDEMGKTDISPGNFQDSFQSARDIESKMRSETRLKLFTLDPDTQRLDLSGIEPDVKQFEEKFGKRVLVCCNDLSFNLQSCVAENEEGPTTNVEPFFVVLSLFDVQNSRKISADFHVDLNHPLVRSLIPSPSMQINGGVDTPHGETLLSELQGMLHYPKKGVFSVTCPHPDIFLVARIEKVLQGGITHCAEPYMKSSDSSKVAQKVLKNAKMACSRLGQYRMPFAWAARPVFKDASGTLDKSARFSALYRQDSNKLSEEDLFKLLADFRKPEKMAKLPVILGNLDVTIDNVPPDMANCVTPSYIPVRPFESNGPNDGVLLEVEEFVPCIAKCSQPFTTYNNHLYVYPKHLKYDNQKSFAKARNIAVCVEFRESDEEDAQALKCIYGRPGGPVFTKHAYAAVLHHQQNPEFYDEIKIELPTQLHEKHHLLFTFYHISCDSSTKKRDIVETPVGSAWLPLLKDGRVVMSEQHISVASNLPNGYLSCQEGVSKHSSPEIKWVDGGRPLFRVSTHLVSTIYTQDQHLHNFFHHFHSMQSGAPRPTEGELVKYLKSLHAMEGHVMINFLPTILNQMIHVLTSATNEDVAVNTTRVMVHIVAQCHEEGLEHYLRSYVKYVFKTESYSNGNSKTVHEELAKAMTSILKPSTDFLTSNKLLKYSWYFFEALVKSMAQYLMESGKVKLSRNQRFTASFHHAVETLVNMLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARSQDGVGFMVPDRKSLTLPVSRNRGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 2063, "header": "tr|A0AC58JTR1-1|A0AC58JTR1_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X7 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=1 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JTR3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AC58JTR3-1", "sequence": { "sequence": "MQGKAGRAARKDAVCETPQQGRTLGEMEVDGDTAMPVGVKPKVIEPLDYENVLVQRKTQILSDVLRDMLQFPIDDFQISTLKRQGRTLYSSVPDGAEKRASSLLVQECIKTYNSDWHVVNYKYEDYSGDFRQLPNKVPRPEKLASHVFEVDEDADKEEDAASLGSQRGGVSKHGWLYKANMNSAISVTMKSFKRRYFHLTQLGDGSYNLNFYKDEKISKEPKGTIFLDSCMGVIQNSKVRRFAFELKMQDKSTYLLAADSEGEMDDWISTLNKILHSSFELAMQERRNGELHDDDEMGKTDISPGNFQDSFQSARDIESKMRSETRLKLFTLDPDTQRLDLSGIEPDVKQFEEKFGKRVLVCCNDLSFNLQSCVAENEEGPTTNVEPFFVVLSLFDVQNSRKISADFHVDLNHPLVRSLIPSPSMQINGGVDTPHGETLLSELQGMLHYPKKGVFSVTCPHPDIFLVARIEKVLQGGITHCAEPYMKSSDSSKVAQKVLKNAKMACSRLGQYRMPFAWAARPVFKDASGTLDKSARFSALYRQDSNKLSEEDLFKLLADFRKPEKMAKLPVILGNLDVTIDNVPPDMANCVTPSYIPVRPFESNGPNDGVLLEVEEFVPCIAKCSQPFTTYNNHLYVYPKHLKYDNQKSFAKARNIAVCVEFRESDEEDAQALKCIYGRPGGPVFTKHAYAAVLHHQQNPEFYDEIKIELPTQLHEKHHLLFTFYHISCDSSTKKRDIVETPVGSAWLPLLKDGRVVMSEQHISVASNLPNGYLSCQEGVSKHSSPEIKWVDGGRPLFRVSTHLVSTIYTQDQHLHNFFHHFHSMQSGAPRPTEGELVKYLKSLHAMEGHVMINFLPTILNQMIHVLTSATNEDVAVNTTRVMVHIVAQCHEEGLEHYLRSYVKYVFKTESYSNGNSKTVHEELAKAMTSILKPSTDFLTSNKLLKYSWYFFEALVKSMAQYLMESGKVKLSRNQRFTASFHHAVETLVNMLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNVRDASNFNTNQNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 2051, "header": "tr|A0AC58JTR3-1|A0AC58JTR3_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X10 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=1 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JTR4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AC58JTR4-1", "sequence": { "sequence": "MLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARSQDGVGFMVPDRKSLTLPVSRNRGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 1073, "header": "tr|A0AC58JTR4-1|A0AC58JTR4_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X13 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=1 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JTR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AC58JTR5-1", "sequence": { "sequence": "MLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNVRDASNFNTNQNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 1061, "header": "tr|A0AC58JTR5-1|A0AC58JTR5_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X14 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=1 CANONICAL=A0A8M9PMK7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JTR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7/entry#A0AC58JTR8-1", "sequence": { "sequence": "MLMPHITQKYKDNLDAARNANHSLAVFIKRCFTFMDRGFVFKQINNYITCFVPGDPKTLYEFKFEFLRVACNHEHYVPLNLPMPFGKGRIQRFQDLQLDYSLTDDFCRNHFLVGLLLREVCGALQEFGEVRQIAIQVLKSLMIKHTFDDRYVSKSQQARLATLYLPLFGLLQENVHRLNNGRDEHLASIPSATPQKPVGNLDNSLHKDVFGVISGTASPHTSTPNIGSVRHADSRGSLISTDSGNSLPDKTNEKTGSLEKTQSASALGSSMLRCDKLDREEIKNLLMCFLHVLKSMSEDALFTYWNKATTSELMDFFTLVEVCLHQFRYMGKRFIARGSVMHTRLHQLGSLENSHTFNHTYCHADADACLLEANISTEVCLTVLDTLSVFIMGFKTQLCADLGHNPLMKKVFQVHLCFLQIPQSETALKQVFTSLRTFIYKFPCTFFDGRADMCACLCYEILKCCNSKLSSIRSDAAHLLYFLMKSNFEYNGRKSFVRTHLQVVIAVSQLIADVIGIGGTRFQQSLSIINNCANSDKTVKHTAFPSDVKDLTKRIRTVLMATEQMKEHEKDPEMLVDLQYSLAKSYTSTPELRKTWLDSMAKIHVKNGDLSEAAMCYVHVAALVAEYLKRKGMFRQGCCAFRVITPNIDEEAAMMEDVGMQDVHFNEEVLMELLEACADGLWKAERYELISDIYKLIIPIYEQRRDFEKLAHLYDTLHRAYTKVMEVMHSGKRLLGTFFRVAFFGQGFFEDEDGKEYIYKEPKFTPLSEISQRLLKLYSDKFGQENVKMIQDSGRVNPKDLEAKFAYIQVTHVTPYLEEKELEERKTDFERSHNIRRFVFETPFTESGKRHGGVEEQCKRRTVLTTTHCFPYVKKRIAVMYQHHTDLSPIEVAIDEMSGKVAELRALCATSEVDMIRLQLKLQGSISVQVNAGPLAYARAFLDDACAKKYPDNKVKQLKEVFRQFVEACGQALAVNERLIKEDQQEYHDEMKASYRDLARELSNIMHEQISAVDGGNKSALSDSLHIFNAISGTPTSTTLHGMPSSASTV", "length": 1050, "header": "tr|A0AC58JTR8-1|A0AC58JTR8_DANRE Computationally mapped isoform of Dedicator of cytokinesis protein 9 isoform X15 OS=Danio rerio OX=7955 GN=dock9b PE=3 SV=1 CANONICAL=A0A8M9PMK7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 611, "start_aa": "Thr", "end_pos": 611, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr611", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 852, "start_aa": "Thr", "end_pos": 852, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr852", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0KZN9-1", "protein_name": "Dedicator of cytokinesis 10", "gene_name": "Dock10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCAPSIVLLQAFRSVVQRSCPHICRRRQEEPSHEIVPLESDEEMMSRPRTLIMQEKPRLLEPLDYETVIEELEKTYRDDALQDLLFFPSDDFSTATVSWDIRTLYSTVPEEAEHRAESLLVKEACKFYSSQWYVVNYKYEQYSGDIRQLPRAEHKPEKLPSHSFEVDHEDADKDEDTTSHSSSKGGGGAGGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGRKSAELAELGLDPLDNSVACECTLEETDSSENSLHPDFAKYLTETEDTVKTTRNTDRLNLFSLDPDIDTLKLQKRDLFEHEFMIKPFEEKAAKRIMIICRALNLNLQGCVTENENDPVTNIEPFFVSVALYDLRDNRKISADFHTDLNHPAVRQMLSGAPPALENGNIDPGTLRQSEEPHIKGLPEEWLKFPKQAIFSVSDPHSEIVLVAKVEKVLMGNIGSGTEPYIKNPDSNKFAQKILKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLYRQESNKISSEDLLRLVSDYRRADRISKMQTIPGSLDIVVDNIPLEQPNCVTSSFIPVKPFDVMAQSEPTVEVEEFIYDSTKHCRPYRVYKNQIYVYPKHLKYDSQKCFNKARNITVCIEFKNSDDDGARPMKCIYGKPGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHGKHHLLFSFYHITCDINAKANAKKKEALETSVGYAWLPLMKHDQIASQEYNIPIATTLPPNYLSIQDPASAKHGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFRQCQKREKDMSQSPTSSFVRACKNLLNVDKIHSIMSFLPIILNQLFKILVQNEEDEITGTVTRVLADIVAKCHEEQLDHSVQSYIKFVFKTRSYKERTIHEELAKNLSDLLKSNDSTIVKHVLKHSWFFFAIILKSMAQHLIDTDKIQLPRAQRFPESYQSELDNLVMGLCDHVIWKCKDALEETKRANHSVARFLKRCFTFMDRGFVFKMVNNYVSMFSSGEFKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESIQELHASDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDIRHLALAVLKNLMAKHSFDDRYREPRKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQTQTSMKHATSVDTSFSKDVLNSIAAFSSIAISTVNHADSRASLASLDSNPSTAEKSSEKTDNCEKIPRPLSLIGSTLRFDKLDQAETRSLLMCFLHIMKTISDETLIAYWQRAPSPEVSDFFSILDVCLQNFRYLGKRNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLPQWMHTTSGHEGHKQHRSQTLPIIRGKNALSNPKLLQMLDNTMNSNSNEIDIVHHVDTEANIATEVCLTILDLLSLFTQVHQRQLQQSDCQNSLMRRVFDTYMLFFQVNQSASALKHVFASLRLFVCKFPSAFFQGPADLCGSFCYEVLKCCNHRSRLTQMEASALLYFFMRKNFEFNKQKSIVRSHLQLIKAVSQLIADAGIGGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHIAALIAEYLKRKGYWKMEKICTPPLLPEDTHPCDSNLLLTTPGGGSMFSMGWPAFLSITPNIKEEGAMKEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQAVGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFETPFTLSGKKHGGVAEQCKRRTVLTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKVSELNQLCTTEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLGELSAIMNEQLCRGPCLYSFCSSVSSISLSTVSKSDYGQGRPSKVRTGATLHHTCN", "length": 2209 }, "evidence": [ { "id": "FB:FBgn0260486", "url": "https://alliancegenome.org/gene/FB:FBgn0260486#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2AF47-1", "protein_name": "Dedicator of cytokinesis protein 11", "gene_name": "Dock11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKLVEPLDYENVITQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLIMLKKIIQINTDSLVQEKKDTVEAIQEEETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDVKPFEEKCNKRFMVNCHDLTFNILGHIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGTSTQLSNDGNAKGFSPESLIHGIAESQLCYIKQGIFSVTNPHPEIFLVVRIEKVLQGNITHCAEPYIKNSDPIKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDVQGSLDLDGRFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLSITVECVPVDLPNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKSFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRVITLEQQLPVSANLPPGYLNVNDAESRRQSNADIKWVDGAKPLLKIKTHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLESYLRSFIKYSFRPEKPSTLQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPEAYHHVLHSLLLAIIPHVTIRYAEIPDESRNGNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPSSASRDEFPCGFVSPTNRGSLASDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDPGSTSENTRQSSSRSSVSQYNRLDQYEIRNLLMCYLYIVKMISEDTLLTYWNKVSPQELINILVLLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSATTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKNQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRSFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPTEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKFAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQVNLKPIDVATDEIKDKTAELHKLCSSVDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNESQANKYPPKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMNNTLHVFCAISGTSSNRGYGSPRYAEV", "length": 2073 }, "evidence": [ { "id": "FB:FBgn0260486", "url": "https://alliancegenome.org/gene/FB:FBgn0260486#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LQ91-1", "protein_name": "Dedicator of cytokinesis 11", "gene_name": "Dock11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKLVEPLDYENVITQRKTQIYSDPLRDLLMFPMEDISLSVIGRQLRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVEAIQEEETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDVKPFEEKCNKRFLVNCHDLTFNILGHIGDNAKGPPTNVEPFFITLALFDVKNNCKISADFHVDLNPPSVREMLWGMSTQLANDGNTKGSSPESLIHGIAESRLCYIRQGIFSVTNPHPEIFLVVRIEKVLQGNITHCAEPYIKNSDPIKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDLQGSLDLDGKFSPLYKQDSSKLSNEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLPNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKSFAKARNIAVCVEFRDSDESDTSALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRVTTLEQQLPVSANLPPGYLNVNDAESRRQSNADIKWVDGAKPLLKIKTHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLESYLRSFIKYSFRPEKPSTLQAQLIHETLATTMIAILKQSADFLAINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPEAYHHILHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFVFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFVSPTSRGSLATDKEPAYGSFQNGHGIKREDSRGSLIPEGATGFPDPGSTGENTRQSSSRTSVSQYNRLDQYEIRNLLMCYLYIVKMISEDTLLTYWNKVSPQELINILVLLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSATTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKSQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRSFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPTEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHIKNGDFSEAAMCYVHVAALVAEFLHRKKLFPSGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEVISEISKLIIPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISFRLVKLYGEKFGTENIKIIQDSDKVNAKELDPKFAHIQVTYVKPYFDDKELTERKTEFERNHNINRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPITCEQQVNLKPIDVATDEIKDKTAELHKLCSSADVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNESQANKYPPKKVNELKDMFRKFIQACSIALELNERLIKEDQIEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMNNTLHVFCAISGTSSNRGYGSPRYSEV", "length": 2073 }, "evidence": [ { "id": "FB:FBgn0260486", "url": "https://alliancegenome.org/gene/FB:FBgn0260486#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9PCG3-1", "protein_name": "Zizimin, isoform K", "gene_name": "Ziz", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MERKFTRGLNKLGSAVQMRENVSQLVRESAVLNKPLVVEPIDFEAFIAKNKTVIQNDPQRELLIYPTDDVSEIIMPRKQRTNAKSVADRFDPPNEAIVCPLHGPSMITNGNGHSQVSRQGSIQSNGSHHNGNGNGHTSSSSSSSLNNSNGHGQLSRKSSQCSNGSSSQKDSSYESALSSITLRSNLAQPEEVDEFADDGNAEDLVDGQPHGSRAECTRFTRQALYTYRAKNHLIHYKYNAYGGNCHDLPSISPAEELVEEIYEIDADQDRIDEQMTRSQADTITKQGYLLKGPDSASDRMFANIGNKSFKRRYCYLRQEIDGTYILELHKDEKQGEAKATIVMDFCTDVVQNPKRGRFCFELRMTTGHKSFTLAAENEQDFKDWLSKISSVLAQNRAQEEKRNASLERHPSIGSNPSPQLQPPAMDPPTFGTLKGLDQSLHPQLMKYGRETDHSIALARREQRRRLFACYQSPVKGSGSDNVEQYREHFGTRLLLTCHNLRFRLQCIPQDESSAGGVEQQVEPYITSLALFDAKANRKLSENFYFNVNEQWAAQLLPNTPVPSSVAGCGVPRKSAEGDERSTACQAPHSLFDGVSAELLRSNRQQFQQLRQCLLSVTAPHADIYLVVRIEKILQSGIAQVTEPYLKAGKDPKLGQKVYKAAKSYAQHIGHYRQPFAWAARPLFKQYSHELDVDPKREFEFSPIYRQEIPKLKDEELLKLLVDYRKPEKLSKLTIIPGSLKMQMQFLDQTTPCGLSKSLAPLSTFSPSSKQSPTVEVAEFQSQSERDAHPYTSFCNHLYVYPLSLQFDSQKLFSRARNITVVVELRDGDGEYSKPLKCIYGRPGQDLLVSQIACPVLHHNVTPTWYEEIKLRLPLGLFPEHHLLFSFYHVSCNLSKKRDANAAFETPIGYAWLPLLQKNRICLEEQQLPVAATLPVGYLSIQPLGWGKGNCGPDIQWIDNQRNLYTVGLRLDSTVLTADQHLHNFFGHCERLLEGGKTGAVPAETETCKILKAAHAIDMKSLINYLPTVLNELFTLLVHTQSEEIGLNVIRLITNIIHLISDQAKRSDLLGAYVKYVFHAPYYSQQTARQRTVHGELCRHLPYLLNPSNPDFLIVNKFMRYSSIFFDLIIKSMAQHLLATGRIRMLRNERFPKEYGDRVEQLIKALMPYITTRFEDLSEETHLLNRSLAKFVRQCLSYMDRGFVFRLIRCYMGEFSPGNPRILHEYKFNFLQEICQHEHYVPLNLPFVLNPKNRPPEMMQHFTLSEQFCRQHFLSGLLLQELKSSLNEVGHVRRHALGIFKDLLAKHELDNRYQQKGQLSRIALLYVPWLGVVMDNIHRIDDLSESGACTPNGHVYADSASYTKRLSCSSSYVFSKDSSTFGSLTSTPRSKNRLTMHCDQASPYRTSVHMKEHNYLAAIAGQPISNGISNLSLNSNTDSGHSQDTTTIGAYTNGDTDVALRNGHNRSVSVTHAQILSRCDKFSSVESKDLLLGFLFIIKHLSQEQMIGWWQNCNESETLQFLSILDLCLLQFRYVGKKSVVITTETRQGRLAKANTLPARTQPPTGLENGSQEQQPSSGTLNQTREHLLEDIDTLARNQLALYESNLATEVGMIILDCLGLYVLQFRQLLADSLVLPKVARVYLRFLQLGQSERLSKHVFAALRAFINNYAVALFKGNAMLCGQMVYELLKACDSRLVEIRHESCAVLYLLMRSNFEFSGRKALTRVHLQVIISVSQMIGNVIGLNNARFQESLSIINSYANSDKAMKGTGFPMEVKDLTRRVRTVLMATAQMQAHHMDPERLLELQYSLANSYASTPELRHTWLVTMARNHEQNGNLSEAACCHLHIAALMCEYLRLKGGCTLSWSSTAFGKISTNIPLDEQGLKLDAGAQDSQYTEQMLLEQLKLCADFLDRAERFECLGELYKLILPMYERDRSYQDLAHCYEHLTQAYNKIVEVNRSGKRMLGRFYRVVFYGLMYFEEDHAIEFVYKEPKLTSLSEISERLAKQYKEKFGADVVKMIMDSSPVKVDELDAKLAYIQVTHVIPFFSKDELDQRLNEFEQNHDVDTFMYETPFTKSGAARGSVEEQWKRKTVIKTQYSFPYVLKRIPVKSREIIELSPIEVAIDEMQSKVSELEEIILPPADVKKLQLRLQGSVAVTVNAGPLAYAHAFLDAKVVNNFSMDRVGDLKDVFRDFIVVCQKALFLNERIISADQKEYHHVLKENYEKLCQALSELLDDESFQPLGDDADSINQRNSMALFNAISGASHNSRPYFVDQNTSNSTHHHSSHINTQNSTHHS", "length": 2298 }, "evidence": [ { "id": "HGNC:14132", "url": "https://alliancegenome.org/gene/HGNC:14132#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090916-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090916-2#orthology", "database": "AGR" }, { "id": "MGI:106321", "url": "https://alliancegenome.org/gene/MGI:106321#orthology", "database": "AGR" }, { "id": "FB:FBgn0260486", "url": "https://alliancegenome.org/gene/FB:FBgn0260486#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5JSL3-1", "protein_name": "Dedicator of cytokinesis protein 11", "gene_name": "DOCK11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEVRKFTKRLSKPGTAAELRQSVSEAVRGSVVLEKAKVVEPLDYENVIAQRKTQIYSDPLRDLLMFPMEDISISVIGRQRRTVQSTVPEDAEKRAQSLFVKECIKTYSTDWHVVNYKYEDFSGDFRMLPCKSLRPEKIPNHVFEIDEDCEKDEDSSSLCSQKGGVIKQGWLHKANVNSTITVTMKVFKRRYFYLTQLPDGSYILNSYKDEKNSKESKGCIYLDACIDVVQCPKMRRHAFELKMLDKYSHYLAAETEQEMEEWLITLKKIIQINTDSLVQEKKETVETAQDDETSSQGKAENIMASLERSMHPELMKYGRETEQLNKLSRGDGRQNLFSFDSEVQRLDFSGIEPDIKPFEEKCNKRFLVNCHDLTFNILGQIGDNAKGPPTNVEPFFINLALFDVKNNCKISADFHVDLNPPSVREMLWGSSTQLASDGSPKGSSPESYIHGIAESQLRYIQQGIFSVTNPHPEIFLVARIEKVLQGNITHCAEPYIKNSDPVKTAQKVHRTAKQVCSRLGQYRMPFAWAARPIFKDTQGSLDLDGRFSPLYKQDSSKLSSEDILKLLSEYKKPEKTKLQIIPGQLNITVECVPVDLSNCITSSYVPLKPFEKNCQNITVEVEEFVPEMTKYCYPFTIYKNHLYVYPLQLKYDSQKTFAKARNIAVCVEFRDSDESDASALKCIYGKPAGSVFTTNAYAVVSHHNQNPEFYDEIKIELPIHLHQKHHLLFTFYHVSCEINTKGTTKKQDTVETPVGFAWVPLLKDGRIITFEQQLPVSANLPPGYLNLNDAESRRQCNVDIKWVDGAKPLLKIKSHLESTIYTQDLHVHKFFHHCQLIQSGSKEVPGELIKYLKCLHAMEIQVMIQFLPVILMQLFRVLTNMTHEDDVPINCTMVLLHIVSKCHEEGLDSYLRSFIKYSFRPEKPSAPQAQLIHETLATTMIAILKQSADFLSINKLLKYSWFFFEIIAKSMATYLLEENKIKLPRGQRFPETYHHVLHSLLLAIIPHVTIRYAEIPDESRNVNYSLASFLKRCLTLMDRGFIFNLINDYISGFSPKDPKVLAEYKFEFLQTICNHEHYIPLNLPMAFAKPKLQRVQDSNLEYSLSDEYCKHHFLVGLLLRETSIALQDNYEIRYTAISVIKNLLIKHAFDTRYQHKNQQAKIAQLYLPFVGLLLENIQRLAGRDTLYSCAAMPNSASRDEFPCGFTSPANRGSLSTDKDTAYGSFQNGHGIKREDSRGSLIPEGATGFPDQGNTGENTRQSSTRSSVSQYNRLDQYEIRSLLMCYLYIVKMISEDTLLTYWNKVSPQELINILILLEVCLFHFRYMGKRNIARVHDAWLSKHFGIDRKSQTMPALRNRSGVMQARLQHLSSLESSFTLNHSSTTTEADIFHQALLEGNTATEVSLTVLDTISFFTQCFKTQLLNNDGHNPLMKKVFDIHLAFLKNGQSEVSLKHVFASLRAFISKFPSAFFKGRVNMCAAFCYEVLKCCTSKISSTRNEASALLYLLMRNNFEYTKRKTFLRTHLQIIIAVSQLIADVALSGGSRFQESLFIINNFANSDRPMKATAFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLIDLQYSLAKSYASTPELRKTWLDSMAKIHVKNGDFSEAAMCYVHVAALVAEFLHRKKLFPNGCSAFKKITPNIDEEGAMKEDAGMMDVHYSEEVLLELLEQCVDGLWKAERYEIISEISKLIVPIYEKRREFEKLTQVYRTLHGAYTKILEVMHTKKRLLGTFFRVAFYGQSFFEEEDGKEYIYKEPKLTGLSEISLRLVKLYGEKFGTENVKIIQDSDKVNAKELDPKYAHIQVTYVKPYFDDKELTERKTEFERNHNISRFVFEAPYTLSGKKQGCIEEQCKRRTILTTSNSFPYVKKRIPINCEQQINLKPIDVATDEIKDKTAELQKLCSSTDVDMIQLQLKLQGCVSVQVNAGPLAYARAFLNDSQASKYPPKKVSELKDMFRKFIQACSIALELNERLIKEDQVEYHEGLKSNFRDMVKELSDIIHEQILQEDTMHSPWMSNTLHVFCAISGTSSDRGYGSPRYAEV", "length": 2073 }, "evidence": [ { "id": "FB:FBgn0260486", "url": "https://alliancegenome.org/gene/FB:FBgn0260486#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63603-1", "protein_name": "Dedicator of cytokinesis protein 9", "gene_name": "Dock9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "KLSRGHSPLMKKVFDVYLCFLQKHQSEMALKNVFTALRSLIYKFPSTFYEGRADMCASLCYEVLKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISLSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKEADLALQREPPVFPYSHTSCQRKSRGGMFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERLRAGLLTSINSSSPSMKSGGTLETTHLYDTLHRPYSKVTEVITRAAGSWDLLPGGLFGQGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKFAYIQVTHVTPFFDEKELQERKTEFERCHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELHQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREIRKELSDIIVPRICPGEDKRATKFPAHLQRHQRDTNKHSGSRVDQFILSCVTLPHEPHVGTCFVMCKLRTTFRANHWFCQAQEEAMGNGREKEPGL", "length": 720 }, "evidence": [ { "id": "HGNC:14132", "url": "https://alliancegenome.org/gene/HGNC:14132#orthology", "database": "AGR" }, { "id": "MGI:106321", "url": "https://alliancegenome.org/gene/MGI:106321#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BIK4-1", "protein_name": "Dedicator of cytokinesis protein 9", "gene_name": "Dock9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCTTSVILFKGIRTVFERNCAYMCKQPGESNALEYTAYNWSKEDSELSIAFCLAKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYLRSTVPANAEEEAQSLFVTECIKTYNSDWHLVTYKYEDYSGEFRQLPNKVPKLDKLPVHVYEVDEEADKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVIQNNRVRRFAFELKMQDKSSYLLAADSEAEMEEWVTVLNKILQLNFEAAMQEKRNGDPHEDDEQSKLEGSGSGLDSYLPELAKSTREAEIKLKSESRVKLFYLDPDTQKLDFSSAEPEVKPFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLAPTSPALMNGGQSPPAFQDALHTAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSITHCAEPYMRSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDTSGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDSVSCDFPNYLNSSYIPMRQFETCSKSPITFEVEEFVPCIPKHTQPYTVYSNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSALAAVLHHQQNPEFYDEIKIELPAQLHERHHLLFTFFHVSCDNSTKGSTKKKDAVETQVGFSWLPLLKDGRVLTSEQHIPVSANLPSGYLGYQELGMGRHYGPEVKWVEGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQASGSELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKFAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENNKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRVIAISMLKNLLIKHSFDDRYNSRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNPGSIVKDEALAVPAGNPLMTPQKGNTLDHSLHKDLLGAISGIASPYTASTPNINSVRNADSRGSLISTDSGNSLPDRNPEKSNSLDKQQQSGMLGNSVVRCDKLDQSEIKSLLMCFLYVLKSMSDDALFTYWNKASTAELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSVTFNHSYGHSEADVVHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSEMALKNVFTALRSLIYKFPSAFYEGRADMCASLCYEVLKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRIIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKGMFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKFAYIQVTHVTPFFDEKELQERRTEFERCHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSDIMREQMG", "length": 2055 }, "evidence": [ { "id": "HGNC:14132", "url": "https://alliancegenome.org/gene/HGNC:14132#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090916-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090916-2#orthology", "database": "AGR" }, { "id": "MGI:106321", "url": "https://alliancegenome.org/gene/MGI:106321#orthology", "database": "AGR" }, { "id": "FB:FBgn0260486", "url": "https://alliancegenome.org/gene/FB:FBgn0260486#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BZN6-1", "protein_name": "Dedicator of cytokinesis protein 10", "gene_name": "Dock10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQEKPRLLDPLDYETVIEELEKTYRDDPLQDLLFFPSDDFSTATVSWDIRTLYSTVPEEAEHRAESLLVKEACKFYSSQWYVVNYKYEQYSGDIRQLPRAEHKPEKLPSHSFEVDHEDADKDEDTTSHSSSKGGGGAGGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGRKSAELAELGLDPLDNCVTCECTLEETDSSENSLHPDFAKYLTETEDTVKTTRNMGRLNLFSLDPDIDTLKLQKRDSFENELMIKPFEEKAAKRIMIICRALNFNLQGCVTENEYDPVTNIEPFFVSVALYDLRDNRKISADFHVDLNHPAVRQMLSGTPPALENGNIDTGTPRQSEEPHIKGLPEEWLKFPKQAVFSVSDPHSEIVLVAKVEKVLMGNIGSGAEPYIKNPDSNKFAQKILKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLYRQESSKMSSEDLLKLVSDYRRADRISKMQSIPGSLDIAVDNIPLEHPNCVTSSFIPVKPFNVSAQSEPTVEVEEFIYDSTKYCRPYRVYKNQIYVYPKHLKYDSQKCFNKARNITVCIEFKNSDDDGAKPMKCIYGKPGGPLFTSSAYTAVLHHSQNPDFSDEVKIELPTQLHGKHHLLFSFYHITCDINAKANAKKKEALETSVGYAWLPLMKHDQIASQEYNIPIATTLPPNYLSIQDPTSAKHGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFRQCQKREKDMSQSPTSSFVRACKNLLNVDKIHSIMSFLPIILNQLFKILVQNEEDEITATVTRVLADIVAKCHEEQLDHSVQSYIKFVFKTKSYKERTIHEELAKNLSDLLKSNDSTIVKHVLEHSWFFFAIILKSMAQHLIDTNKIQLPRAQRFPESYQSELDNLVMGLCDHVIWKCKEAPEETKRANHSVARFLKRCFTFMDRGFVFKMVNNYISMFSSGEFKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESIRELHASDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDIRHLALAVLKNLMAKHSFDDRYREPRKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQTQTSMKHATSVDTSFSKDVLNSIAAFSSIAISTVNHADSRASLASLDSNPSTTEKSSEKTDNCEKIPRPLSLIGSTLRFDKLDQAETRSLLMCFLHIMKTISDETLIAYWQRAPSPEVSDFFSILDVCLQNFRYLGKRNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHTTSGHEGHKQHRSQTLPIIRGKNALSNPKLLQMLDNSMNSNSNEIDIVHHVDTEANIATEVCLTILDLLSLFTQVHQRQLQQSDCQNSLMKRVFDTYMLFFQVNQSASALKHVFASLRLFVCKFPSAFFQGPADLCGSFCYEVLKCCNHRSRLTQMEASALLYFFMRKNFEFNKQKSIVRSHLQLIKAVSQLIADAGIGGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHIAALIAEYLKRKGYWKMEKICTPPLLPEDTQPCDSNLLLTTPGGGSMFSMGWPAFLSITPNIKEEGAMKEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFETPFTLSGKKHGGVAEQCKRRTVLTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSRKVSELNQLCTTEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSAIMNEQITGRDDPAKCGVERPYTTRVTSKGTAAVPVVSISSSAEV", "length": 2187 }, "evidence": [ { "id": "FB:FBgn0260486", "url": "https://alliancegenome.org/gene/FB:FBgn0260486#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96BY6-1", "protein_name": "Dedicator of cytokinesis protein 10", "gene_name": "DOCK10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGERTRRFTRSLLRPGQAAELRHSAASAAAVAVSSRQQQRQEKPRLLEPLDYETVIEELEKTYRNDPLQDLLFFPSDDFSAATVSWDIRTLYSTVPEDAEHKAENLLVKEACKFYSSQWHVVNYKYEQYSGDIRQLPRAEYKPEKLPSHSFEIDHEDADKDEDTTSHSSSKGGGGAGGTGVFKSGWLYKGNFNSTVNNTVTVRSFKKRYFQLTQLPDNSYIMNFYKDEKISKEPKGCIFLDSCTGVVQNNRLRKYAFELKMNDLTYFVLAAETESDMDEWIHTLNRILQISPEGPLQGRRSTELTDLGLDSLDNSVTCECTPEETDSSENNLHADFAKYLTETEDTVKTTRNMERLNLFSLDPDIDTLKLQKKDLLEPESVIKPFEEKAAKRIMIICKALNSNLQGCVTENENDPITNIEPFFVSVALYDLRDSRKISADFHVDLNHAAVRQMLLGASVALENGNIDTITPRQSEEPHIKGLPEEWLKFPKQAVFSVSNPHSEIVLVAKIEKVLMGNIASGAEPYIKNPDSNKYAQKILKSNRQFCSKLGKYRMPFAWAVRSVFKDNQGNVDRDSRFSPLFRQESSKISTEDLVKLVSDYRRADRISKMQTIPGSLDIAVDNVPLEHPNCVTSSFIPVKPFNMMAQTEPTVEVEEFVYDSTKYCRPYRVYKNQIYIYPKHLKYDSQKCFNKARNITVCIEFKNSDEESAKPLKCIYGKPGGPLFTSAAYTAVLHHSQNPDFSDEVKIELPTQLHEKHHILFSFYHVTCDINAKANAKKKEALETSVGYAWLPLMKHDQIASQEYNIPIATSLPPNYLSFQDSASGKHGGSDIKWVDGGKPLFKVSTFVVSTVNTQDPHVNAFFQECQKREKDMSQSPTSNFIRSCKNLLNVEKIHAIMSFLPIILNQLFKVLVQNEEDEITTTVTRVLTDIVAKCHEEQLDHSVQSYIKFVFKTRACKERTVHEELAKNVTGLLKSNDSTTVKHVLKHSWFFFAIILKSMAQHLIDTNKIQLPRPQRFPESYQNELDNLVMVLSDHVIWKYKDALEETRRANHSVARFLKRCFTFMDRGYVFKMVNNYISMFSSGDLKTLCQYKFDFLQEVCQHEHFIPLCLPIRSANIPDPLTPSESTQELHASDMPEYSVTNEFCRKHFLIGILLREVGFALQEDQDVRHLALAVLKNLMAKHSFDDRYREPRKQAQIASLYMPLYGMLLDNMPRIYLKDLYPFTVNTSNQGSRDDLSTNGGFQSQTAIKHANSVDTSFSKDVLNSIAAFSSIAISTVNHADSRASLASLDSNPSTNEKSSEKTDNCEKIPRPLSLIGSTLRFDKLDQAETRSLLMCFLHIMKTISYETLIAYWQRAPSPEVSDFFSILDVCLQNFRYLGKRNIIRKIAAAFKFVQSTQNNGTLKGSNPSCQTSGLLSQWMHSTSSHEGHKQHRSQTLPIIRGKNALSNPKLLQMLDNTMTSNSNEIDIVHHVDTEANIATEVCLTILDLLSLFTQTHQRQLQQCDCQNSLMKRVFDTYMLFFQVNQSATALKHVFASLRLFVCKFPSAFFQGPADLCGSFCYEVLKCCNHRSRSTQTEASALLYFFMRKNFEFNKQKSIVRSHLQLIKAVSQLIADAGIGGSRFQHSLAITNNFANGDKQMKNSNFPAEVKDLTKRIRTVLMATAQMKEHEKDPEMLVDLQYSLANSYASTPELRRTWLESMAKIHARNGDLSEAAMCYIHIAALIAEYLKRKGYWKVEKICTASLLSEDTHPCDSNSLLTTPSGGSMFSMGWPAFLSITPNIKEEGAMKEDSGMQDTPYNENILVEQLYMCVEFLWKSERYELIADVNKPIIAVFEKQRDFKKLSDLYYDIHRSYLKVAEVVNSEKRLFGRYYRVAFYGQGFFEEEEGKEYIYKEPKLTGLSEISQRLLKLYADKFGADNVKIIQDSNKVNPKDLDPKYAYIQVTYVTPFFEEKEIEDRKTDFEMHHNINRFVFETPFTLSGKKHGGVAEQCKRRTILTTSHLFPYVKKRIQVISQSSTELNPIEVAIDEMSKKVSELNQLCTMEEVDMIRLQLKLQGSVSVKVNAGPMAYARAFLEETNAKKYPDNQVKLLKEIFRQFADACGQALDVNERLIKEDQLEYQEELRSHYKDMLSELSTVMNEQITGRDDLSKRGVDQTCTRVISKATPALPTVSISSSAEV", "length": 2186 }, "evidence": [ { "id": "FB:FBgn0260486", "url": "https://alliancegenome.org/gene/FB:FBgn0260486#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9BZ29-1", "protein_name": "Dedicator of cytokinesis protein 9", "gene_name": "DOCK9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQPPLLPASAETRKFTRALSKPGTAAELRQSVSEVVRGSVLLAKPKLIEPLDYENVIVQKKTQILNDCLREMLLFPYDDFQTAILRRQGRYICSTVPAKAEEEAQSLFVTECIKTYNSDWHLVNYKYEDYSGEFRQLPNKVVKLDKLPVHVYEVDEEVDKDEDAASLGSQKGGITKHGWLYKGNMNSAISVTMRSFKRRFFHLIQLGDGSYNLNFYKDEKISKEPKGSIFLDSCMGVVQNNKVRRFAFELKMQDKSSYLLAADSEVEMEEWITILNKILQLNFEAAMQEKRNGDSHEDDEQSKLEGSGSGLDSYLPELAKSAREAEIKLKSESRVKLFYLDPDAQKLDFSSAEPEVKSFEEKFGKRILVKCNDLSFNLQCCVAENEEGPTTNVEPFFVTLSLFDIKYNRKISADFHVDLNHFSVRQMLATTSPALMNGSGQSPSVLKGILHEAAMQYPKQGIFSVTCPHPDIFLVARIEKVLQGSITHCAEPYMKSSDSSKVAQKVLKNAKQACQRLGQYRMPFAWAARTLFKDASGNLDKNARFSAIYRQDSNKLSNDDMLKLLADFRKPEKMAKLPVILGNLDITIDNVSSDFPNYVNSSYIPTKQFETCSKTPITFEVEEFVPCIPKHTQPYTIYTNHLYVYPKYLKYDSQKSFAKARNIAICIEFKDSDEEDSQPLKCIYGRPGGPVFTRSAFAAVLHHHQNPEFYDEIKIELPTQLHEKHHLLLTFFHVSCDNSSKGSTKKRDVVETQVGYSWLPLLKDGRVVTSEQHIPVSANLPSGYLGYQELGMGRHYGPEIKWVDGGKPLLKISTHLVSTVYTQDQHLHNFFQYCQKTESGAQALGNELVKYLKSLHAMEGHVMIAFLPTILNQLFRVLTRATQEEVAVNVTRVIIHVVAQCHEEGLESHLRSYVKYAYKAEPYVASEYKTVHEELTKSMTTILKPSADFLTSNKLLKYSWFFFDVLIKSMAQHLIENSKVKLLRNQRFPASYHHAVETVVNMLMPHITQKFRDNPEASKNANHSLAVFIKRCFTFMDRGFVFKQINNYISCFAPGDPKTLFEYKFEFLRVVCNHEHYIPLNLPMPFGKGRIQRYQDLQLDYSLTDEFCRNHFLVGLLLREVGTALQEFREVRLIAISVLKNLLIKHSFDDRYASRSHQARIATLYLPLFGLLIENVQRINVRDVSPFPVNAGMTVKDESLALPAVNPLVTPQKGSTLDNSLHKDLLGAISGIASPYTTSTPNINSVRNADSRGSLISTDSGNSLPERNSEKSNSLDKHQQSSTLGNSVVRCDKLDQSEIKSLLMCFLYILKSMSDDALFTYWNKASTSELMDFFTISEVCLHQFQYMGKRYIARTGMMHARLQQLGSLDNSLTFNHSYGHSDADVLHQSLLEANIATEVCLTALDTLSLFTLAFKNQLLADHGHNPLMKKVFDVYLCFLQKHQSETALKNVFTALRSLIYKFPSTFYEGRADMCAALCYEILKCCNSKLSSIRTEASQLLYFLMRNNFDYTGKKSFVRTHLQVIISVSQLIADVVGIGGTRFQQSLSIINNCANSDRLIKHTSFSSDVKDLTKRIRTVLMATAQMKEHENDPEMLVDLQYSLAKSYASTPELRKTWLDSMARIHVKNGDLSEAAMCYVHVTALVAEYLTRKEAVQWEPPLLPHSHSACLRRSRGGVFRQGCTAFRVITPNIDEEASMMEDVGMQDVHFNEDVLMELLEQCADGLWKAERYELIADIYKLIIPIYEKRRDFERLAHLYDTLHRAYSKVTEVMHSGRRLLGTYFRVAFFGQAAQYQFTDSETDVEGFFEDEDGKEYIYKEPKLTPLSEISQRLLKLYSDKFGSENVKMIQDSGKVNPKDLDSKYAYIQVTHVIPFFDEKELQERKTEFERSHNIRRFMFEMPFTQTGKRQGGVEEQCKRRTILTAIHCFPYVKKRIPVMYQHHTDLNPIEVAIDEMSKKVAELRQLCSSAEVDMIKLQLKLQGSVSVQVNAGPLAYARAFLDDTNTKRYPDNKVKLLKEVFRQFVEACGQALAVNERLIKEDQLEYQEEMKANYREMAKELSEIMHEQLG", "length": 2069 }, "evidence": [ { "id": "HGNC:14132", "url": "https://alliancegenome.org/gene/HGNC:14132#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090916-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090916-2#orthology", "database": "AGR" }, { "id": "MGI:106321", "url": "https://alliancegenome.org/gene/MGI:106321#orthology", "database": "AGR" }, { "id": "FB:FBgn0260486", "url": "https://alliancegenome.org/gene/FB:FBgn0260486#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMK7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMK7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1030, "end_pos": 1032, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1401, "end_pos": 1403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1417, "end_pos": 1419, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2060, "end_pos": 2062, "annotation": "n_glycosylation_sequon" }, { "start_pos": 897, "end_pos": 899, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7" }, { "id": "PS51650", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51650" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 DOCK-type", "eco_id": "ECO_0000259", "start_pos": 651, "end_pos": 824, "start_aa": "Asn", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7" }, { "id": "PS51651", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51651" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DOCKER", "eco_id": "ECO_0000259", "start_pos": 1627, "end_pos": 2054, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PMK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMK7" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 188, "end_pos": 295, "start_aa": "Gly", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 611, 852 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1030, "end_pos": 1032 }, { "start_pos": 1401, "end_pos": 1403 }, { "start_pos": 1417, "end_pos": 1419 }, { "start_pos": 2060, "end_pos": 2062 }, { "start_pos": 897, "end_pos": 899 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UUW9-1", "uniprot_ac": "A0A8N7UUW9", "uniprot_id": "A0A8N7UUW9_DANRE", "mass": { "chemical_mass": 116691.0, "monoisotopic_mass": 116691.0 }, "refseq": { "ac": "XP_690098", "name": "NLR family CARD domain-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690098" }, "gene_names": [ { "name": "si:ch211-196h16.5", "type": "recommended", "evidence": [ { "id": "A0A8N7UUW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUW9" } ] }, { "name": "si:ch211-196h16.5", "type": "synonym", "evidence": [ { "id": "XP_690098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690098" } ] } ], "protein_names": [ { "name": "NLR family CARD domain-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_690098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690098" }, { "id": "A0A8N7UUW9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUW9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_690098.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_690098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690098" } ] } ], "disease": [ { "disease_id": "DOID:0050854", "recommended_name": { "id": "DOID:0050854", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "Muckle-Wells syndrome", "description": "A syndrome characterized by episodic skin rash, arthralgias, and fever associated with late-onset sensorineural deafness and renal amyloidosis that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q44." }, "synonyms": [ { "id": "DOID:0050854", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "MWS", "description": "" }, { "id": "DOID:0050854", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "neutrophilic urticaria", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle-Wells syndrome", "description": "An intermediate form of cryopyrin-associated periodic syndrome (CAPS) and is characterized by recurrent fever (with malaise and chills), recurrent urticaria-like skin rash, sensorineural deafness, general signs of inflammation (eye redness, headaches, arthralgia/myalgia) and potentially life-threatening secondary amyloidosis (AA type)." }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle-Wells syndrome", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "neutrophilic urticaria", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "MWS", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle Wells syndrome", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "urticaria, deafness and amyloidosis", "description": "" }, { "id": "MIM:191900", "resource": "MIM", "url": "https://www.omim.org/entry/191900", "name": "Muckle-Wells syndrome", "description": "Muckle-Wells syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050854", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050854" } ] }, { "disease_id": "DOID:0080208", "recommended_name": { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol." }, "synonyms": [ { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "nonalcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "non-alcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "NAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-related steatotic liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MASLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic-associated fatty liver disease", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "NAFLD2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "fatty liver disease, nonalcoholic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "liver disease, alcoholic, susceptibility to, 1", "description": "" }, { "id": "MIM:613282", "resource": "MIM", "url": "https://www.omim.org/entry/613282", "name": "Non-alcoholic fatty liver disease 1", "description": "Non-alcoholic fatty liver disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ] }, { "disease_id": "DOID:0080270", "recommended_name": { "id": "DOID:0080270", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080270", "name": "autosomal dominant nonsyndromic deafness 34", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q44." }, "synonyms": [ { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "hearing loss, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "DFNA34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "autosomal dominant nonsyndromic deafness 34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "deafness, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MIM:617772", "resource": "MIM", "url": "https://www.omim.org/entry/617772", "name": "Deafness, autosomal dominant, 34, with or without inflammation", "description": "Deafness, autosomal dominant, 34, with or without inflammation" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080270" } ] }, { "disease_id": "DOID:0090029", "recommended_name": { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "CINCA Syndrome", "description": "An autoimmune disease characterized by neonatal onset of cutaneous symptoms, chronic meningitis, and joint manifestations with recurrent fever and inflammation that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q." }, "synonyms": [ { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "IOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "NOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic infantile neurological cutaneous articular syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "Chronic Infantile Neurological, Cutaneous, and Articular (CINCA) syndrome is characterized by skin rash, joint involvement, chronic meningitis with granulocytes and, in some cases, sensorineural hearing loss and ocular signs." }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA/NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Neonatal-Onset Multisystem Inflammatory Disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic infantile neurological cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal onset multisystem inflammatory disease", "description": "" }, { "id": "MIM:607115", "resource": "MIM", "url": "https://www.omim.org/entry/607115", "name": "Chronic infantile neurologic cutaneous and articular syndrome", "description": "Chronic infantile neurologic cutaneous and articular syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090029", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090029" } ] }, { "disease_id": "DOID:0090062", "recommended_name": { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "familial cold autoinflammatory syndrome 1", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP gene on chromosome 1q44." }, "synonyms": [ { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "FCAS1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "Any familial cold autoinflammatory syndrome in which the cause of the disease is a mutation in the NLRP3 gene." }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "NLRP3 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP3", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome type 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold inflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "FCAS1", "description": "" }, { "id": "MIM:120100", "resource": "MIM", "url": "https://www.omim.org/entry/120100", "name": "Familial cold autoinflammatory syndrome 1", "description": "Familial cold autoinflammatory syndrome 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090062", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090062" } ] }, { "disease_id": "DOID:0090063", "recommended_name": { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "familial cold autoinflammatory syndrome 2", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP12 gene on chromosome 19q13." }, "synonyms": [ { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "An autoinflammatory disease caused by mutations in the NLRP12 gene. It is characterized by periodic fevers beginning in the first year of life that are triggered by cold exposure. Episodes occur more than once per month." }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NALP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NAPS12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome type 2", "description": "" }, { "id": "MIM:611762", "resource": "MIM", "url": "https://www.omim.org/entry/611762", "name": "Familial cold autoinflammatory syndrome 2", "description": "Familial cold autoinflammatory syndrome 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090063" } ] }, { "disease_id": "DOID:12351", "recommended_name": { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "alcoholic hepatitis", "description": "" }, "synonyms": [ { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic hepatitis", "description": "" }, { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic liver disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12351" } ] }, { "disease_id": "DOID:1555", "recommended_name": { "id": "DOID:1555", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1555", "name": "urticaria", "description": "A skin disease characterized by skin rash notable for pale red, raised and itchy bumps, located_in the upper dermis." }, "synonyms": [], "unlinked_id_list": [ "DOID:0060220" ], "evidence": [ { "id": "1555", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1555" } ] }, { "disease_id": "DOID:3590", "recommended_name": { "id": "DOID:3590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3590", "name": "gestational trophoblastic neoplasm", "description": "" }, "synonyms": [ { "id": "DOID:3590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3590", "name": "gestational trophoblastic neoplasia", "description": "" }, { "id": "DOID:3590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3590", "name": "hydatidiform mole", "description": "" }, { "id": "DOID:3590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3590", "name": "molar pregnancy", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "hydatidiform mole, recurrent, 1", "description": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the NLRP7 gene." }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "NLRP7 complete hydatidiform mole", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "complete hydatidiform mole caused by mutation in NLRP7", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "hydatidiform Mole, recurrent, type 1", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "hydatidiform mole, recurrent, 1", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "HYDM1", "description": "" }, { "id": "MIM:231090", "resource": "MIM", "url": "https://www.omim.org/entry/231090", "name": "Hydatidiform mole, recurrent, 1", "description": "Hydatidiform mole, recurrent, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "3590", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3590" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:9452", "recommended_name": { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes." }, "synonyms": [ { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Fatty change of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Steatosis of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "alcoholic fatty liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic lipidosis", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "SLD", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "fatty liver disease", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "fatal neonatal hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUW9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUW9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-196h16.5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUW9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUW9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UUW9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "561595", "url": "https://www.ncbi.nlm.nih.gov/gene/561595", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561595", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561595", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UUW9", "url": "https://www.orthodb.org/?gene=A0A8N7UUW9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_690098", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690098", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UUW9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUW9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUW9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TRH4", "url": "https://www.uniprot.org/uniprotkb/A0AB32TRH4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TRH4-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TRH4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TVJ5", "url": "https://www.uniprot.org/uniprotkb/A0AB32TVJ5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TVJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TVJ5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58FYJ9", "url": "https://www.uniprot.org/uniprotkb/A0AC58FYJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58FYJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58FYJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081029-8", "url": "https://zfin.org/ZDB-GENE-081029-8", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKGNTGFRVKPPEPSGVSMKSDRSMHHPLKFKGGIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDPMFRPPEPSVSEKSGQSVDPTLKFSVHTCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDIGEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSINLFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQLDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLRLRCCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLCRCGVSDEGCAALVSVLSSNSSNLRELNLTENKVGDSGVKLLSAGLKENSKLEKLWLFICGVSDEGCAALASILRSNSSNLRELDLTGNKVGDSGVKLLSAGLKDPHCKLEKLTLDFCGVSDEGCAALASALRSNSSNLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC", "length": 1041, "header": "tr|A0A8N7UUW9-1|A0A8N7UUW9_DANRE Isoform 1 of NLR family CARD domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-196h16.5 PE=4 SV=1 CANONICAL=A0A8N7UUW9-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UUW9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUW9/entry#A0A8N7UUW9-1", "sequence": { "sequence": "MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKGNTGFRVKPPEPSGVSMKSDRSMHHPLKFKGGIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDPMFRPPEPSVSEKSGQSVDPTLKFSVHTCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDIGEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSINLFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQLDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLRLRCCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLCRCGVSDEGCAALVSVLSSNSSNLRELNLTENKVGDSGVKLLSAGLKENSKLEKLWLFICGVSDEGCAALASILRSNSSNLRELDLTGNKVGDSGVKLLSAGLKDPHCKLEKLTLDFCGVSDEGCAALASALRSNSSNLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC", "length": 1041, "header": "tr|A0A8N7UUW9-1|A0A8N7UUW9_DANRE Isoform 1 of NLR family CARD domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-196h16.5 PE=4 SV=1 CANONICAL=A0A8N7UUW9-1" }, "locus": {} }, { "isoform_ac": "A0AB32TRH4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUW9/entry#A0AB32TRH4-1", "sequence": { "sequence": "MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKGNTGFRVKPPEPSGVSMKSDRSMHHPLKFKGGIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDPMFRPPEPSVSEKSGQSVDPTLKFSVHTCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDIGEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSINLFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQLDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLRLRCCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLDFCGVSDEGCAALASALRSNSSNLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC", "length": 926, "header": "tr|A0AB32TRH4-1|A0A8N7UUW9_DANRE Computationally mapped isoform of NLR family CARD domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-196h16.5 PE=4 SV=1 CANONICAL=A0A8N7UUW9-1" }, "locus": {} }, { "isoform_ac": "A0AB32TVJ5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUW9/entry#A0AB32TVJ5-1", "sequence": { "sequence": "MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKGNTGFRVKPPEPSGVSMKSDRSMHHPLKFKGGIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDPMFRPPEPSVSEKSGQSVDPTLKFSVHTCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDIGEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSINLFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQLDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLRLRCCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLFICGVSDEGCAALASILRSNSSNLRELDLTGNKVGDSGVKLLSAGLKDPHCKLEKLTLDFCGVSDEGCAALASALRSNSSNLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC", "length": 984, "header": "tr|A0AB32TVJ5-1|A0A8N7UUW9_DANRE Computationally mapped isoform of NLR family CARD domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-196h16.5 PE=4 SV=1 CANONICAL=A0A8N7UUW9-1" }, "locus": {} }, { "isoform_ac": "A0AC58FYJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUW9/entry#A0AC58FYJ9-1", "sequence": { "sequence": "MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKGNTGFRVKPPEPSGVSMKSDRSMHHPLKFKGGIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDPMFRPPEPSVSEKSGQSVDPTLKFSVHTCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDIGEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSINLFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQLDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLRCCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLCRCGVSDEGCAALVSVLSSNSSNLRELNLTENKVGDSGVKLLSAGLKENSKLEKLWLFICGVSDEGCAALASILRSNSSNLRELDLTGNKVGDSGVKLLSAGLKDPHCKLEKLTLDFCGVSDEGCAALASALRSNSSNLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC", "length": 983, "header": "tr|A0AC58FYJ9-1|A0AC58FYJ9_DANRE Computationally mapped isoform of Protein NLRC3 isoform X3 OS=Danio rerio OX=7955 GN=si:ch211-196h16.5 PE=4 SV=1 CANONICAL=A0A8N7UUW9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561595", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561595", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JW23-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPATAKDALHRLSTYLEELEAGELKKFKLYLGIAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGEDLVRVTPSNGLCSLESQSTCLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGPWCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTSRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFTAMYCALHGREAVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAEDGPPEPPGAQTQSTHSQERNILPDIYSAYLSATICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIANRNLIRLDLSGNSIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSNNSHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVNTCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGISQTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFGMDLNKVTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1PS14-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:dkey-222h21.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNMLQRIKNQHKTSLKNKYERLFEGIEVKETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPENLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGIDVSDASVYSGICTEILKEESVIQQRKVYSFIHLSFQEFLAAFHVFYHHITCSTEASLDSLHDLQKRIINKSTESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKRSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELKLQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITPGLRKYACVLTLDPNTAHTHLVLSEKNRQARNVTDPQPYPDHPDRFKNNEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYSCDTIYTVWHNNKSADIIAPSACTNRVGVYVDVPSGSLSFYSVTDTHTLTLIHTFNTTFTEELYTGFGIYPEASVSLCQI", "length": 892 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RJ47-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "si:ch211-201o1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSAEKSDDAPATGSSPEDLQAEQHEQKKSDSSTVSHVSMKSGRSITPPLDFRKDEQGNTERAKQERAESSTASHLSMKSDRSITPPLDFISGEQKQTERKSVDDHAVSTSADRVCQRHHRALDVFCQTDNIHICCICVEEEHQGHRKTYTAKLNVPDSQSMLLHIMEKMRSEDFNTFKRELSEDYAGCLGAQSEELSVSEAAENIMRSFGGEAALRLILHFQTKANPLKKITDANKTKLKNKCQNINEGNSSYGKQSLLMEVYTDLYFTEGGSGEINNEHEVLRNEMISQSRTTQEVLYACDEIFKTLPGQRTQVRTVLTMGIAGIGKHVSVQKFILDWAEGKANQDIEIIIHLPFRDLSCREESCSLLQLVHQYSPELREADLQHLKVLFILDGLELCQYPLHFHKNVYCADINEKVPVDALLTNLIKGNLLPSALLWITTRPSTAGRIPPECVHRVTEIRGFSDDQKDSYFRKKISDQTLADEIIRHIKSCQSLYIMCHMPIFCWISATVLENIMREGQSEELPRTLTGMFTHFLLLQVSLKHKKFNGADGDNPKKLSEFDQTFILKLGELAFQQMEKGDLIFREEDLREGGIDVSKVSEYSVCTEFFREELGLYREKLYGFLHVSYQEFLAAIYAHFTCVNDGRNVFLKDESRSSVDLCDVHQTAVEKALQSENGHLDLFLRFLLGLSVDSNFNLLQDLLKDTSCKPRVDTSSTVSFIKEKVKLEQSPERIINLFHCLNQLNDNSLVEEIKAAMKSGTLLGSELDPEQWSALAYVYLTSGEEIEEFDMIKSNQLRLLPVLRICKKARLNCCNLSFASCGLVASALKSVNSPLTELDLSNCKLNIFGMNTLLDGLKSPHSKVKKLRLAGCFFPSETCANLALALKSVNSQVTELDLSYNKITDGVHKFCAGLTSQNCKLQKLVLKRCGLTKASCAHLASVLKSNTHLMELELKGNDLQDSGVELLSTGLMDPQCRLEKLGLSGCMITKVGCNSLASALTSNADCMSELDLTYNHPGDSGVKLLTAKKEDPNCKLEKLHVKKRGECRMKPGLRKYACQLTVDPNTIHPRLIVSNDNRTISETTEHQKYPVHPDRYTLYPQAMCREPLADRSYFEVKCTGGVSIGVAYKTSDRTEDLMGFNNTFPSLMCLNGRIKLWQNNDVIHYELPVFAQSSRVGVYVDQYQGSLSYYSICKDTLIHLHTHHTEFTSPLYIGFLFMPDSSVTLLDDSL", "length": 1231 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AHM3-1", "protein_name": "Uncharacterized protein si:dkey-23k10.3 isoform X1", "gene_name": "si:dkey-23k10.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVFLHTTHLYSGQTEVSGYKSTVLRSFVRPSYILKFERNCYHEFSRIHLLSTLLQWQVNLETLRFSACGITDEACFALAKALTSKLSHLRELDLSENKLGDAGVMVLSAALENNCSDLVSLKMNDCDLTYEGCSHLASALASNPSHLRELDLSKNKLDDVEMLVLAAGLENSSCKLEKLRLVKCGLTDEGFVVLNKALRSNPSHLKELDLSENSLCYLHTMLLSSVLESPYWELKTLKLVNCSFTEEGGAALMSALRSNPSHLRELDLSKNNIGYLTMMVLSSAMEIPYWELEILRLNDCGITDDGFAALGAGLRSNPSYLRELDLSKNKLGEFGVHMLSIALEMPYCQLETLRLVSCDITGNGWIVLVSALRSNPSHLRNLDLSGNNLECFEIKLLSEVLESPYCKLETLKLRNCNLKDEECVSLASALRLKISKLRELDLSENKLGDSGVKAFFAELEGHLSKFDALRFVNCGLTDEGCGVLASVLSSNPSHLKELDLSGNKVEDSGVKMLSDGLEDYCCRLETLKLVGCGLTDEGCASLASALTSNSSHLRVLDLSKNKLSDSGVRLISTGLENPHCKVEILWLVDCDVNDEGCAALASALTFNFSNLRELDLSENNLGDFGVKLLSAGLEDPHCKLEILKLKNCGFTDGGIAALAPVLGSDHSYLKNVDLSGNKFEDFGVQLLSIAFY", "length": 692 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3ANC0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch73-168d20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSRKRRSSSPESSCVSIKSDASMDNPPTLRLGESPAKHRRSSSLGSSCVSMKSDASMDNPPTLRLGESPAKHRRSSSPESSCVSMKSDASMDNPPTLRLGESPAKHSDNQKRSQSNKGQKQLDAIFKDLEETNIDEMRKVLRRFKMLLSPDYSVRDEEEEEGQRQINEAFLKITLHALQKMNQTDLASKLQTKLISVSQQQLKSRLKQRFERFTEGVSNRGNTKLLNDIYTEVYITEGGAGNIDDEHEVRQIETSSSRFPEIPIRCCDIFKSLLGQDKAIRTVLTKGVAGIGKTASVQKFILDWAEGKANQDVHFIFPLPFRDLNLIKEKRMSLMELLCCFCPELKPIDYNNFKTVFIYDGLDEWRLPLDFRNNEILWDMNKVASVDALLTNLLQGNLLPSAVHWITTRPAAACQIPAEFIDRVTEVRGFKDLQRAEYFWKRIKDQNLANKIITHIQSSRSLHIMCRIPVFCWISATVLEKIFGEANSADIPKTLTQMFIHLLIVQTNLKTQKYDRECDVNLEKARKSILSLAKLAFEQLEKGNLIFYEEDLKQCGIDVREASVCSGVCTQIFREEFGLQLQKVFSFVHLSVQEFLAALFKFLSFAEENNKSSMTQFMKNEVDRALQSPNGHLDLFLRFLLGLSLDSNQTLLQGLFTPLDTSHSRDETIEYIKSKIRENPSPERSINLFYCLNELNDHSLVQEVQTYLTSTRSHRLSGVKLSPALWSALVFVLLNSTKDLDEFELRQYDFTEECLLRLLPVVKASRKADLKGGNLTDQICSALASALSSSSCCLRELDLSENRLQLSGIRLFSAGLKSPNCKLEILKLSNCSIREEGCASLVSALLSNPSHLRELNLNSNQPGYSTVKLLSDLLENPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLNGSNIREKDCAAFISSLLSNPFHLRELSLSWNKPGDSGVKLLSDLLKDSRCKLEKLELECCSIIEEGCAALALALVSNPSHLRELNLNNNEPGDLGVNLLSFLLKNPQCKLEKLELEYCCIGAKSCASLASAFVSNPSHLRELNLNWNTPEYPAVKLLSDYLKDPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLEYCCIGEEGCAALVSGLKSNPSHLRELNLNRNEPGNLGAKMLSDLLKDPLFELEKLELDDCSIENNGFADLVSGLKSNPSNIRELNLNSNKFIFSGLNLLCDLLRDQQCKLRKLQLECCNIDEEGCAALALALISNPSHLRELNLNYNNPGGLGVKLLSVLLKNPHCKLEKLELSHCSISENYLAALNSALSSNPAHLRELNLNYNENTRQ", "length": 1388 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQ59-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKIFQNLTAESGKGIRDYVVQIRFCFIMDDTQISRDENVSPGCSSVHQKRSDPEPSCVSMRSDWSMDPPISFKSKDTPPDFSSVHQKSTESEPSCVSMRSDDESVDQPLHVRSGDTETDLSHEALNTFRSDLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIIPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLMNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHLLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDGFEEIKKPSLWSKVKDLLYLNSSQLVSLSELHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQIILQRLMILKSRSIQINKTVEYIKMKIRTIDSPEKFINLFHCLNELGDHSLVEEIQQYLKSGRINRAKLSESQWSAVAFVLLTSEKKLEEFHINEFVGETEKIFIFMKLLPVIRECRSVQLNNCGLTDEGCAALASALRSNPEHLRELNLSGNRLGDSVTLLSALLEDPRCNLEILWLSYCGLTDEGCAALASALRLNPEHLRELNLSHNNISKSTVKLLSDLKHNPHNKLETLYI", "length": 837 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B0M3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "si:dkey-7i4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESDEQHNDTLVQMGSSGNSGINADLRAEKEATVIAPLLNGNNITGPVTFNYCSNSAENEPQKYPKTADKHTEKQDDLKLQKILETHRTYMKKKVDCILDCTKENAEHFKAFYTELFIAEGDMQDVNQEHEILKIDDAFKKKKASLRSIRCKDIFAELKAKSEKNTVLTKGIAGIGKTVSVRKFILDWAEGQTNHDIHCVFLLPFREINLMTNEDFNLHEFLLKFYPELKELETSVLFQQCNLAFIFDGLDESRLPLNFKSRTLNNVEERSSVDMLFTSLVKGNLLPSALVWVTSRPAAANQIPPRYVGLFTEVQGFTDQQKEKYFRNRIADETQASKIISHIKTSRSLYIMCHIPVFCWITATVLQDILQRNIESIGTTLTEMYIHFLLIQMNMKSQKYDPEEEREYAKLLEANREVILKLAKLAFEQLKKENVVFYEQDLKDCGIDVNVEFTGMIAEIFKVEHGLHEAKVFYFVHLSVQEFLAAVYVFFCFLNRNTHELTFFFESSQNTPRELQFLFKKTFRKVKFHDLIKRATDKAMRSKRGHLDLFLRFLLGISLESSQNLLKGLFSHVIDTTRSIKKISPHFKHLQNKNISCDCSVNLFFCLLELKDHSLYEEIQRSLNSDRRPSKELSSSMCTVLTYIVLMSEKELDELNPKRFTSSQENYRKLVPAVRCCRKALFNGCGLDEMSFQTISSALQSSDSYLTELELSNNHLQDSGVKLLSDGLKSSHCQLNILRLCGCGLTDQSCESLSSALQSSNSVLRELDMSNNMLKDSGVKLLAVALKSLNCKLERLRFSMCNLTAESCESLSSVVELSNSVLRELDLSNNDLQDSGVKLLSDGLKRNCRLEILRLSGCMVTEVGCGFLSSALSSTTSTLRELDLSYNHPGDSGEKLLSDAHNQPNCRLCVDHGGEFRLTTGLHKYARFFTLDPNTANARLILSEENRKVTCVRKKQPYPDHPDRFEGYLQVLCRESVCGRSYWEIEWTGVVFISVSYSSIGRMGSDKECWFGFSNQSWSLFCSSDRCSFTHSSTEIDLPVKHTSSRIGVYVDHSAGTLSFYSVSDTVSLIHSVQTTFTQPLHPGFYISLGSSVKLC", "length": 1096 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YSM0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch211-181d7.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSHKQTLKYFSPVCSSVQQERSDSAEPSSVSVKSHWSIDPPPQMTERRDSLSLALQERSDSPEPSHVSMKSDWSIDPPPQMKEENRSLVQQERSPKSSCVSMKRDWSIDPPPQMNDEDGQKRLSLVQQERSDSAEPSLVSMKSDWSIDPPPQMKDGDRQKSLSLVQQERSDSPEPSHVTMKSNWSIDPPPQMTDRRDSLRQIPRPRPGAEEPISKKMKYDESVIKSQECMENPSLIFSHEVNTFRVNLLKKFQCLYEGMVTQDNPALLNEIYTELYITESESGEISNEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPETKEIDIFSDKYKILFIFDGLDECRLLLNFKSNEILQHVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLMAQINTKDMKYTGKKDKDMIFKLGKLAYEQLERGNVIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFIHLSVQEHLAALYVHLLFTNHNRNVFEQMTKKTSKTLDILDCFHSNSPENVLLSELHQKAVDEALQSKNGHLDLFLRFLLGLSLESNQILLQELMIKFRSSSDSSEKTVEYIKKRINNICLPEKSINLFYCLNELGDHSLVKEIQQYMDYGTLAETKISCGQWSALVFILLTVEQAMDVFELNKFIGLKKSSDEVLRKLLPVIKKSRSAIMDDCNITAEGCAYLASALGSNPSYLRELDLSANKLQDSGIKKLSKGLQDSHCKLEKLNLYHCGVTNEGCAALASALKSNPEHLRDLNLSENKIGNLGLTCLSEILKNSLCKLEILRLCQCGITDCTDLASALISNPEHLRELELSLNKIGDSGVTALCAAFEDPRFKLEKLGLSGCGLTDEGCAALTSALRSNHEHLRDLDLSGNKVDKEVKGSILQRILEKLNNIQILSV", "length": 1068 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YU37-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch73-24k9.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDNQTFSDAPVCSNESNPEFEPSCVSMKSDQSMDPPMKFKEGHTSADLSDRLNPPGSSCVSMKSDWSMDRPIQFKEEHSSADLSNKSNPGEPSCVSSKSDQSMGPPINVMEEHSAADLRLDPHLKQNGLRSNLLRKFQCLYEGTAMQGDPTLLNEIYTELYITESDSGEINNKHELRQIETRSRRSATEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEEKENQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEQFKVLFIFDGLDECRVSLDFKCDVKLHDVSESASVDVLLTNLIMGNLLPSALIWITSRPAAADLIPSEFVHRVTEIRGFNDPQKEEYFRKRIRDQFLADIIIINLKSSRSLHIMCHIPVFCWISATVLEKIFSQAQSGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEVRDEDMILKLGKLAFEQLVKGNLIFYEEDLRECGLDVTEASVYSGLCTQIFREEFGFYQGKVFCFVHLSIQEHLAALYAHHSLTNKNRNVFKQTKPSLLSKVLNQKKHDSLSVLHQRAVKEASQSKNGHLDLFLRFLLGLSLESSGTLLRELLTQTGSCSYNKEETVQYIKQKIRENRSPERSINLFHCLNELGEDSLMQEIQDYLSSGEIKETKLSSSQWSALVYVLLTSEKKMDFFDLSKFIGPQLRADVVLQKLLPVVKESRSVRLGDCKVTDKVCAALASALRLNSSHLTQLDLIGNKLGDSGVKLLSDGLKDPHCKLKNLMMRDCGVTDEGCAALASALRSNSTHLTELNLNENNLGDAGVKRLSDGLKGPHCKLEILRLWRCGVRDEGCAALASALSSNSTHLKELELSDNKLGDSGVKLLSDALKDPHCKLEKLRLNGCGVREQGCVSLALALRFNPSSHLTELDLTSNELGKSGVKLLSDLRDDPRYKLRHLACDMFGRIIVSSGGGRLDELLPTTSTET", "length": 978 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkey-165e24.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHRVRSGSCVSSSVSLKSDCSKEDPPKFSEKTPSSAQSVRSGLCVSSFVSLKSDCSKEDPPKFSEKTPSSAQSDEDELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNELEKFKQILQEENRQEFVKDYNENRSRITEAALDLTLFFLREMKQDHAADTLQDELLFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAVSRRHQSLETQVEFKHLFKAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQLFPETKGLNLTRSTQFKVLFILDGLDECRLPPNFAGNEMCCDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILNLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSQGKLAFQQLERNNVIFYESDLNDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEGIIAYIKQKLEGNLSPERSINLFYCLSELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELWKFQRSDECLIRLSAIIKNSKRALLQSCNLTVQSCKSLSSILQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLATCNLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSEHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDTLNLDHVGDMRITAGPRKYVCFLTLDPNTANTQLKLSKENRKVKHVREDLRIMRKDRRYPYHPDRFDPVFQVLCRESVCGRCYWEIDWSGDHGVFISVSYKSIRRKRGDACEFGCNAQSWSLLCLSSRFTFRHNNTHTHVPVKPLSRRIGVFVDHSAGTLIFYNIYKDTMSLIHSVQTTFTEPLCPGFGFYSGSSVKLS", "length": 1137 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1F5-1", "protein_name": "Protein NLRC3", "gene_name": "si:dkey-23k10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METEGPDSPEPSCVSLRSDHSKAHHVLFKDEDPFEYSSGQTGRSSPTPSHVSLASNMSINQPLEFKSCSNTLLLKEIQEAIQSVLRIRFQCLHEGLSKHSVLIPLNDIYTELYITEGEGGELNNEHEIRWIETACRRALTEDRPVNLNDIFKPLHGQDRPIRTVLTKGVAGIGKTVSVQKFIIDWAEGEANQDIWFIFPLPFRELNLLKDQSFSLKGLLQYFMNIELDISLHEGKIMFIFDGLDECRLPLDFHNNVKLCDVTESASVDVLLTNIIRGNLLPSSLIWITSRPAAADVVPSKCIHRVTEVRGFSDPQKEEYIRKKVSDQTLSDRIISHLKSSRSLYIMCHIPVFCWISATVLKKMLSEAESAEIPNTLTQMYTQFLMLQLRIKNEKAYDKKSSDIDIVLKLGELAFQQLEKLNLIFYKEDLREYGIDEQEASVYSGLFREESGMFQGKVYSFVHLSVQEHLAALYVYLYFVNENINKLNQPNFLTSILKCVPTVFDVYQTAVKKALQSTSGHLDLFLRFLLGFSLESNQNLLGDLQVQTESSSDSREQIVGFIKEKIKESPPPEKMINLFHCLNELNDHSLVEEIQDFLQSESRINMKLTASQWSAMVFVLLTSGQKLDVFDLNKYIGTYILPDESLQRLQPVLAASRTAKLCEHNLTKRGYSVLVSVLTSKTSCLRELNLTRSAVNDSGLKLLCSGLENPQCKLETLRLEFCGVSDKGCDFLASALRSNPSHLKALDLSGNTLNFTGLKNLLAEFQKPHCKLQRLCLRLCGLTDVGCDALASVLRSDPSHLTELNLSGNKLGDLGMKLLAGGLQNPHCKLQILRLGDCSITHEGCAALASALRSNPSHLRELDLSGNKLNNAGVQILSGELENPDCNLEILRLENCDVGEEGCAALAEALKSNPLTLKELDLCWNKLGNSGVQRLCTSLENPNCTLGVLRLTGCNISENGCAALASVLRSNPSYLRDLDLSHNDLRSSGVRLLSSALEKPDCKLEILRLEYCKITDDGCAVLASALKSNPSHLRELYLYMNSFNLTASGRQLLSKIKDDPHYKLQTLHYESHFFC", "length": 1074 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z5L8-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch211-207e19.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKDFNENRSRITDAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTDHEIRQIEAASRRHQSLEIQVECKHLFEAAEQHEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETEGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVDKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKKQGWFFIQISKNKGMIDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKGEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSADLSPAQWSALVFVLLTSEEELEVFELQKFQRSDECLIRLSAVIKTSKRALLQGCYLTVRSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLQFCNLTVQCCESLSSALQSSNCVLRELDLSINDLQDSGVKKLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKYVCFLTLDPNTAHTELILSEENREVKSVRENQPYPDHPDRFDYYHQVLCRESVCGRCYWEIDWSGDGVVCISVSYKSIRRKGGGDECVFGYNAQSWSLRCDSSRFKFWHNNTHTDLPVEALSSRIGVFVDHSAGILIFYNIYRDTMSLIHSVQTTFTEPLCAGFRVYYPGSSVKLS", "length": 995 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PCI8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTQTTIEKDYSPRFSLVHQKRSEPSCVSIRRDQSVAHPIDFKSEDTQTHLSSVHQERLDPEPSCVSIRSDRSVAHPIDFKSKNTHLSSVHQERSEPEPSCVSIRSDRSVAHPIDFKSEDTQTHLSTFHQKRKEADPSCVSMRSDTFMNQPINIKIGETQNDLKQNLLNTFRSNLLKKFECLYEGTAVQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQNKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSEKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCLNNNRNEFEQISKQSLWSKVRDHFHFNSSKLVSISKLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQGLMKLKIRSIQNNETVEYIKKKIRKINFPEKFINLFHCLNELGDHSLVEEIQQFLKSGGMNEAKLSSSQWSAVVFVLLTSEKKLEKFDINEFAARNNNTEQLFIFKKLQPVIRQCRSVQLSYCGLTDEGCAALASALRSNPEHLRDLYLSGNKLGDSVSLLSGVLEDPHCKLETLWLSDCGLTSKDSAALASALRSNPEHLRVLDLSWNRLGDSVTLLSAVLEDPHCKLETLLLRDCGLTDEGCAALASALRSNPEHLKHLDLSWSNLGDSVTLLSAVLEDPRCKLEKLGLSNCGLAEEGCAALASALRSNPEHLRGLNLSVNNLGDSVTLLSAVLEDPRCKLEKIKLSYCGLTDEGCAALASALRSNPEHLRDLDLSTNNLGDSVTLLSAILEDPHCKLEKLELKNCGLTDEGCAVLASALRSNPEHLRDLNLSWNNLSNSTKKLLSDLKDDPHNKLETLHTSLSV", "length": 1115 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PLT8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "nlrc8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSMNHPKHFKSGETQNDLGSAHQKRSDPEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQKRSDPEPSCVSMKSDWSMDPPMQFKSKDTPPDLSSVHQERSEPEPSCMSMNSDLPLDPPIRYKSGETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQSLWSKTKFMFKTVALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLKLKRRSIKNNKTVEYIKKKIRTIDSPEKSINLFHCLNELGDHSLVEEIQQYLKSGGINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAENNKTEKLVIFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTLLSAVLEDPHCKLEKLWLSYCGVTDEGCAALVSALRSNPEHLRELNLSGNNLGDSVTLLSAVLEDPHCKLEKLRLYYCGLTDEGCAALASALRSNPEHLRDLDLSWNKLGDSVTLLSAVLEDPRCKLEKLELYNCGLTDEGCAALASALRSNPEHLRDLNLSGNKLGDSVTLLSAVLEDPRCKLEKLWLSDCGLTDEGCAALASALRSNPEHLTELDLSWNNLSKSTVRLFSDLKDNPHNKLKTLHI", "length": 1017 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPT2-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSKRKREDEDAASEISSASPGSSCVSVKSDQSMKKNLPDFSDASVTSDLSISKTINQRSASPEFSVLSMTSNRSIGQPENFSDEPVTFDSVLSDALDKPDYEKLHRIKDQHKTSMKNKYERLFEGLKLDETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHRASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFHVFYYHVNTTMDGLRNFASVENLIKGAVDKAIESENGHLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLFREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCGIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTRQKLNWDHGGHFRITPGLRKYACFLTLDPNTAHNQLILSEDKRKVTHVKDPQQYTDYPEKFVHQEQVLCKETLTGRCYWEVEWSGEGTDIAVAYKGIRRKAGSDCWFGYSEKSWSLFYTGNGFNVWHNNKSQIIPAPSPLSNRVGVYLDTESGSLSFYSVSDTHTLTHLHTFNTTFTEPLYAGFRVFDSSLSLCNI", "length": 993 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PSD3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEEQGKMSLSEKHSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKPMSAKSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKQTSAKSVISDSCVSGSVFVKSDCSKDGDLPNFSEETPSSGKSFEHKTSDSDFQTHRKHKGFQDGLLGIFQDLENQIMNYLKHELEKFKKILQKENIIDFVKDFNENRCSIKEAALDLTLYFLREMKQEESADTLEDELIFIHQLKCGLQKKYQCVFEGIAQQGDSRLLKNIYTDLYITQGGSEQVNTEHEVRQIEVASRRHEAQELQVECRHLFEASEQDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQEISFIFPLPFREMNLKEKETLSLMELITQFFPETKGLNLTRRNRFKVLFILDGLDECRLPLNFAGNETCCDVSSPASLDVLLTNLIKGNLLPSALIWITSRPAAASKIPPDCIDRLTEIRGFNDAQKEEYFRKRLTDENQAKEIIDHVKQSKSLFIMCHIPVFCWISATVLQNILQEKRNNDVKHNQADDASKTLQESNTEDTPKTLTQMYTHFLRFQIQQSRRKYNGEYTPDVSWDKDAILSLGKLAFHHLLNNNLIFYDTDLEACGIDVYKASVYSGMCTQIFKEETGIILGTMYCFVHLTLQEFIAALYAHLILDTNKKSVFDQDSKKINESMIDLLKTAVDKALESDNGHLDLFLRFLLGLSLQSNRRILRGLLTPQDQDDQSTEKILQYIKQKFDANLSPERSINLFYCLNELNEQTLVKEIQTHLSKGSLSSADFSSAHWSALAFVLLTSDEEMEEFELQKFHKSDECLIRLSAVIKTCKRALLNDCNLTDRSCSALATVLESDTSLKELNMSNNNLQDSGVKLLCTGLKDMKCELEILRLSDCNITEEGYKALASALRSNPSHLLELDLRGNDPGESGVKELDDLLQDPNCTLKTLRFLSPSAEESCQFVNGVVGKNPLLLKTLNLNDFRSTRNHPFIYEIEDTQVNHLAALLQDKHCRVNMLILGGCSFTDDQWESLTSALKLNPSHLRELILMWNGPGESGVKILSDFLIEPQLKLEKLCLCYCSITEERCEILTSALKSNPSHLRELNLSQNIPGDSGMKNLSDLLMNPQSKLEKLQLCKCSITEEQCVILTSALKSNPSHLRDLNLSLNNLGDSGVKTLSDLLMKPHLKMEKLWLCKCSITEEQCVILASALKSNPSHLRELSLSENNLGDSGVKNLSDLLMKPQFKLEKLHLSHCSITEEQCEILTSALKSNPSHLRELDISKNQIRNTGVNLLCDVLNNSDCKLETLRLNDCGITDVSSLTQCLTNTKALQFLKVLYLRENHIGDSKQELSDVVRDSNCELSVDEFSLPDFGQIKDIKCCIS", "length": 1370 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCS9-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLQKKNEDEDEESASEMSYPPPESSCVSMKSDWSMVYPPDLSDASVTSDPNNSKRKGQHLEFKESSCVSVMSNRSITPPEMKKIGLKSEDNMLEKIKNKHKTSMKHKYERLFEGVKLHENQTLLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVGVSDASVYSGICTEIFKEESVIQQRKVYSFTHLSIQEFLAAFYVFYYHITCSTEACFDSLHDLQRRAVDKAIESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITSGLRKYACFLTLDPITAHTQLQLSEENRKASIVTDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGLVAVAYKGIGRKSGFDCCFGHNEHSWCLYCSDEVYSVWDNNKSVDVFGPSSRTNRVGVYVDVPSGCLSFYSVSDTNTLTHIHTFNTTFTEELYAGFKVYPGSSVSLCPVKPAEVPP", "length": 988 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32T552-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:ch73-50f9.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSGKHSVRSGSCVSRSVSLKSDESRKGLPPEFSEQPPSSNRSVEYELSDSVDKTHCNRKSFTDHLLRIFQDLESKIFKVLKNELERFRQILQGENTQDFVKGSNENQSSITKSALDLTLLFLREMKQDEVADTLENELLFINRLKSSLKKTYQSVSEGIAQQGDSTLLNNIYTDLYITQGANEQVNTEHEIRQIEAASRCHKSLEIQVECKHLFEAPEQDKQIRTVLTKGVAGIGKSVSVQKFVVDWAEGKANQDISLIFPLPFREMNLKEKEKQSLKDLITQLFPEVKGLNLTRRTRNKVLFILDGLDECRLPLNFAGNETCHDVSAPAYLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLADQNLAMEIIEHIKQSKSLHIMCHIPVFCWISATVLQNVLKETKVKHKACAKTLQESPKTLTQMYTHFLRFQMQQSRQKYDGKNTDGVSWDQNFILSLGKLAYQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKQETGIILGNLYCFLHLSIQEFIAALYGHLYLDIKKKSVFTGQKHKNKGMTHLLKTAVDKALESDNGHLDLYLRFLLGLSLQTNRQLLRGLLTQQDKSDQSKEEIVVYIKQKLEENLSPERAINLLYCLNELNDHSLMKEIQSHLRDGSLSSADLSPAQWSALTFVLLTSEEELDEFDLQKFKKSDECLIRLSAVIKSSKRALLQCCNLTAQSCESLSSALQSSNCVLRELELSNNDLQDSGVKLLSCGLRSLNCPLEILRLQCCNLTAQSCESLSLALQSSTCVLRELDLSNNDLQDSGVKLISNGLKSCKLEILRLSGCMVTETGCGFLSSALSSNPTHLRELDLSYNHPGVSGVKLLCQKLEDPNYTLAKLNVDHAGAKRITAGPRKWISHLTLDPNTANTELSLSAENREATRVIEKQPYPDHPDRFDYHPQVLCRESVCGPCYWEIDWSGDVGACISVSYKSVSSKGNDEFGCNDQSWSLSCYSSRFSYGHNNRWTDLPVKPISRRIGVYVDHRAETLRFYNICGNTVHLVHSVRTTFTQPLYAGFKIYPGSSVKLC", "length": 1099 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TA29-1", "protein_name": "NLR family CARD domain containing 9 isoform X3", "gene_name": "nlrc9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTKISKDEDYSPRFSSVHQERSDLEPSCVSMRSEQSMGSPMHFRSEDTEADLSSVYQKRSDPEPSCVSMRSDWSMDLPYNFRSEDTPTDLSSFHHKRTEAEFSRVSMRSDMFINHPINIKNVEAQCNIRQNLLNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFESAVRLCDISESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPMFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDEFEQIKKQSLWFKVKDLFQLNSLECVSLFSLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQRLMKLKSRSMQTNKTVKYIKMKIWTIDSPEKSINLFHCLNELGDHSLVKEIQQYLKSGRINRAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAGNNENKKQKVFQKLLPVIKQSRSVLLYNCGLTEMDWDNLTSALRSNPSDLRVLNLSRNILGNSVTLLSAVLEDPCSKLEKLWLSDCGLTDEGCAALATALRSNPEHLRELNLSWNNLRDSVTLLSAVLEDPRCKLETLWLSKCGITGKSCAVLASALRSNPEHLRDLDLSGNKLGDSVTLLSAVLEDPHCKLKILWLSDCGLTDEGCAALASALRSNPGQLRVLDLSENKLKNSGVMQLCAVLEDPHCKLDKLGLYDCSLTDEGCVALASALRSNPEHLRELDLSVNKLRDSGIKLLSAVLEDPRCKLEKLWLSNCGLTDEACAALASALRSNPEHLRELNLSKNKLGESDVKLLSDLKDDTHYKLKELNY", "length": 1079 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TJY6-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkeyp-100h4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQQIQETRLKGDTRASQTISSPSSSCSMAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKDCPPVFSGETPSSAQSVEFESADSGDETHRRHKSFTDNLQSIFQNLESKMFTFLKNELEKFKKILQENRQEIVKEFNENRSRITEAALDLTIFFLREMKQDQAADTLVGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVKCKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDDQKQEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGFVLHTMYCFLHLSIQEFIAALYQHLILDNDKTQAEKSRDESMIDLLKAAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEANLSPERSINLFYCLNELNDQSLLKQIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAIIKTSKRALLQGCYLTVPSCESLSSVLQSSNCVLRGLDLSNNDLQDSGVNLLSDGLKSQHCKLETLRLVMCNLTVESCESLSSVLQSSNFVLRELDLSNNDLQDSGVKLLSDGLKTVNCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVELLFEKLADPNYTLDKLNLDHGGHTRITAGPRKNACFLTLDPNTTYAFLILSEENREVKTVREYQLYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDDYVDISVSYKSIMRKGVDPECVFGRNAQSWSLCCDSSSFTFWHNDTDTRLPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLWPGFTVWCQSSVKLC", "length": 1125 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TMV3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like", "gene_name": "si:ch211-197e7.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDWSKEDPPKFSEKTPSSAQSVRSGSCVSSSVSLKSDRSKEHPLPNFREKTPSSAQSVEHELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNEMEKFKKILQEENRQEFVKDYNENRSRITEAALDLTLFFLREIKQDQAADTLQDELFSINQFQCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNNEHEIRQLEAASRRHQSLETQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNKTCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKILFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALENENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDESKKKIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFMLLTSEEELEEFELRKFQRSDECLIRLSAVIKTSKKALLQSCNVTVQSCKSLSKVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLAMCNLTVQCCESLSLALQSSNCVLRELDLSNNDLQDSGVKLLSNRLKSQYCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDKLNLDHGGEKRITAGLHKYVCFLTLDPNTAHIQLILSEENRKVKPVREDMMMMRKDQPYPDHPDRFDGLYPQVLCRESVCGCCYWETDWSGDGGVCISVSYKSIRRKGGVECEFGRNAQSWSLHCSSSRFIFIHNNTETRLPVKRLSKRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRVYSGSSVKLS", "length": 1140 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TPE7-1", "protein_name": "Protein NLRC3 isoform X4", "gene_name": "si:dkey-11n14.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKYSVRSGSSSSVSLKSDWSKDEPPKFSEKSPSSARSVEYELPYSGDKTHRSHKGFTKDLPRIFQNLESKIIRYLKNELEKFKKILQEENRQDFVKHFNENRSIITEAALDLTLFFLREMKQDEAADTLEGELFFINQLKCGLKKKYQNVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTTGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKENQSLKDLITQFFPQTKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTKLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISANVLLNILKENRNTELKHRDNSETLHESPKTLTQMYTHFLRFQIQHSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYDSDLKDCGIDVYKASVYSGMCTQIFWEETGIILGTMYCFLHLSIQEFIAALYQHLFLDSDKKHLSIFRQKSKNKVMTDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQNDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSADLSPAQWSAVAFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQGCNLNVRCCESLSSALQSSNCLLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDTLNLNHGGEKRITAGPRKYVCFFTLDPNTANTRLILSKKNREVKCVRENQSYPRHPDRFDDHPQVLCRESVCGRCYWEIDWSGGNEVCISVTYKSIRRKRGYECRFGYNAQSWSLICSSSRFSFTHNDTHTDLPVKPFSRRIGVFVDHCAGTLIFYNIYRDTMSLIHSVQTTFTEPLIPGFWVYSGSSVKLLKTEERFTQNPLQDQ", "length": 1060 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQ28-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:ch211-226o13.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTHTSGDLDLFTSCSVDGDDQTRDLQQDSLQPEHDELQRAKNQHKTSMKNKYERLFEGINHGETQKFLNRIYTQLYIIEGESEGVNREHDVLQIEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQGVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITARPAAAHQIPSTYIHRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDQEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFHCYLTDKREPVMLLYESKYSDDEDVSDGNEYEDSDVQFLQSSSEFSLCHLLSLAIYKAVMSSNGHLDLFLWFLLGVSLESNQRLFQDLLTHTEESSESIRIITQDIKDKIKTDDDLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSERELSPAHCSTISYMIEMSEEPLDELDFNKLNTSPVGRWRLIPAVRNCRRALLQWSYLSVQYCESLFSALKSSNCVLRELDLSTNDLQDSGVKLLSDGLKSPNCKLETLRLQCCNLTAQSCESLTSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCKLETLRLVMCNLTVQCCESLSLALQSSNCVLRELDLSNNGLQDSGVKLLSDGLKSQHCKLDTLRLVMCNLTVQSSESLSSALQSSNCVLRELDLSTNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGLHKYACFLTLDPNTTYAFLILSEENREVKRVREYQQYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDGCSVCTAVSYKSIRRKGRGAECLFGRNAQSWSLCCSSSSFIFRHNYTRTELPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFTVWCQSSVKLC", "length": 1145 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQA8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-29j8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEEQVKDSLSEKQSVRSGSCVSSSVSLKSDNSKGGRTPNFRGKTPSSVKRFFHLGKSKHPPSNLREKTPSSAESFQYELPDSRNKTHRSQKSFRGHLQKIFENLESKIIKFVKKELKNFRKILQNENRQEFVKEFNENSSGITEAALDLTLFFLREMKQDQAADTLQGELLYINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSVVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDTQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVLCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNKVMINLLKTAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQCCNLTVQCCESISSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQQCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGEKRITAGPHKYVCFLTLDPNTAHTRLILSEENREVKCVRENQPYPDHPHRFDYYLQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGAECAFGRNAQSWSLICSSSSFTFRHNNSHTDLTVKPLSRRIGVFVDHSAGTLIFYDIYRDTMSLIHSVQTTFTEPLCPGFYVSYGSSVKLS", "length": 1064 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TTK4-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAMNRLMTDMLEELVEAELKQFTRQLWMGVKPGVDPIPRGKLENKDRQDVVDCMVQHYSKDAGKIAVQALRSIKQNERADRLELNLRKDDDFLGEVLKKHKESIKASVDVFEGKKDNKTDINKVYTELFITEGDMTDVCKEHEVQKFDLALQMPRSEDKPIDCNEIFNLLRGKDKGNVVLTKGIAGIGKTFSVNKFILDWAEGRANLDVDCMFLLPFREINLMIKDGDVSLHKFLLKLFPDITGVETTPFYEKCKLLFIFDGLDESRLDLNFNLSSVDDVHSCASIDGLFTSLIKGRLLRSSLIWVTSRPAAANRIPSYHVGLFTEVRGFTDKQKEEYFRKKVPDEDQASRIISHIRTSRSLYIMCHIPVFCWIIATVLQDILQKNKGEDIPSTLTEMYIHFLLIQMNIKNQKYDEKLIRDRTELLGSNRDMISKLAKLAFEQLKKENVMFYREDLAACGINADEEFTGLCTEIFKKDSVLHELKVYYFIHLSVQEFLAALHVFLCYLELEKDMNLTDSDLMFFLEDSRPKQKELLHVLLRKAIDKAEKSDRGHFDLFLRFLLGISLESNQKLLIGILNETKNSKQSISKTVQYLKQLQNNDKCPDKSINHFFCILELQDRTLYQQIMKYLRSKTNRPKVMSRSNCSALVYVLLMSQEVLDKFNPKLFNKTYAGCRILVPAVRCSRKALFSDCGLTETCFETVALALQLENCPLVELDLSYNYSLEAAVNVMCAGLKSPHCHLESLRLAGCHLGQDSCMQVVSALQSISHRLKELDLSGNDLQDSGLQKLLQGMENTEKRLQVLRLSWCNLTEMSCQQLSTILSSNSVFRELDLSNNDLQDSGVKLLSDGLKSPNCKLKILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHCKLKTLKTDPMGDHLMKPGIVKYAFNLTLNPNTAHVHLLLSDGDRKVTLKEKQPYPDDPERFEEHHQVLSRESLSGRCYWETEWTGQEGTVGVAYESIPRKPDDLLYGRCMLGNNIISWKITCGSRTHVSHAEEDITVKSPSSGSCKRVGVYVDTTAGVLSFYHVFDTLTHLYTFLMPFTQPLYAAFRVDGESVSICPIP", "length": 1114 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TUF4-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch73-236c18.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHHCGNEEVDREEKEKHGAEHSCVSMKSDQSMRNPIAFTDKAVTFDLRSVASSSSHFETHTVQEKTDKGLQTQIFETEELQRVKDQHKTSMRKKYELLSEGIKVKETGTQLNRIYTQLYIIEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFYVFYYHVNTTMMGLKTFASLQKLLKGAVDDAIESKNGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCRLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRIKPGLKKYACFLTLDPNTAHVQIQLSEGNREARNVKDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYCCDTNYTVWYNNESADIIAPSARTNRVGVYLDVSSGSLSFYTVSDANTLTLIHTFNTTFTEPLYTGFGLYPESSVSLCQI", "length": 969 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HUA8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 1 homolog isoform X1", "gene_name": "LOC103910107", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDQDSERAQFVDAHWKTLVQRVIMVMAIADELQSDGMLEWEPYCKIKAAVTNQQKMRELYEVLQSGGDQVKSAFYSSLEKHEPYLLGDLGSIKLMGESLADCLNKYKMWIQKEYEYVTEYNSLPGENVLLSERFTQPLIIMRHRERREREEEMCSVGESFQQLLVSRNNADKDSSILDALFGADSKGISPNSVILQGNSGNGKSFTAQKIMLDWASGKLCKVEFDCLFHLKCKEVNHVSGEQSLTELLSYNSNLTSEQISRILQKSSEKVLILIDGFDELRFSFSDFSDHLKLKDLSEKAPREASLKVLLMGHILSKTSLLVTTRSTATNTLDSLLKHPKRFTEIMGFSEREVKEYFQKFFQDEELFIKAYEYVRSNETLITACSIPVICWIICTVLRERFSEGSDLTSGLETTTSIYVDFVCTLLEHHSQGLSQPVPTLLRSLGQLAERGMLDTQVLFEEKSVDEMVSASPFLCKFLFKRRIRKETMFSFMHLSFQEFFTALYYISQEEREFLDKLTERFHSQTQSYLSLYLDKDFPLKYGCPEPHFLPVVQFLCGLSNSEVSRSLQEMYNLSVPSFVQPQLREWILDMSKSGVYSYLPFILHCLYELHEKEFVQKAMEAWLELDMSWDPLSRTDCWALLYCLDCCPHFRSLKLNFAASELKMLQDVLCRTPKLGLTVQNVSDTDVTVLLSALGEGKQLGELKLNSSCLSDQSVQQVLKALHKQKKVGGLQISVKSITADTALILTDFLQSCSKAEWEEISGSLSTSDVESLCSSLRLFSFEGKLVVNVVRLCLSIQNQPSLSEIILNCPRSEASNIDIKSFTESFHNINCIAEESVDFDRNLHALLTLLTSMSGLSALNLSVPFLTETWASRVLFLVESSPKLTVINFHAGSWCSDGVKWLPGLLLEEGIKLLKESAKRPECIVNIRGFRCSKSSERCSRHTEHIDQLSCNQRVTIQFCGDQCTEDIKLKLVLPDEN", "length": 979 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HZJ9-1", "protein_name": "Uncharacterized protein si:ch211-149a19.3 isoform X1", "gene_name": "si:ch211-149a19.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDKEASNDGDFSSRRSHFQSQKSNTSESNPEITPEDLSAKKLIKMFEKRTPDNQSKFNNQKSNTAKSIRSDRSIQNPVKIKEIRTPADLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPKPMPRSIKSDQSTPELDKVDGGHTSTALSSQRSNPPDPKPRSIKSDQSTPEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGIGCQRSNPPDPKPRSIKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPESSLVSLKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSMPEPIKFDGGHTPTGLSETSTNDQFMNKQVKIKRRHTLTGLSKTSINYQFMEKQLKTERRHTSTGLSLNSKLFENLLKSNLLKKFQCVSEGTSILGNPTLLNEIYTELYITESDSGEINNEHELRQIETQSRRSAKEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEKNKNQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEHYKVLFIFDGLDECRVSLDFDSGVKLHDVSESASVDVLLMNLIMGNLLPSALIWITSRPAAADLIPSGFVHRVTEVRGFNDPQKEEYFRKRIRDQSLADTIISHLKSSRSLHIMCHIPVFCWISATVLEKIFSQAERGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEDKDMILKLGKLAFEQLQKGNLIFYEEDLRECGLDLTEAAVYSGLCTQIFREEFGFSQSKVFCFVHLSIQEHLAALYAHHFLTNNCLNKHWKTFNPLSFLHQRAVNEALQSKNGHLDLFLRFLLGLSLEFNQTLLQELLTQTGSCSYNTEETVQFIKQKIREINSPERSINLFHCLNELGDQSLMKEIQNYLRSGEIKETKLSSSQWSALVYVLLTSEQEMEDFDLNQFIGTQNTADEVLQKLQPVVKESRSVQLSGCSVTDKGCAALALVLRSDSSHLRELDLSENNLRDSGVKLLSDGLKDPHCKLEKLRLSDCGVTDEGCAALASALRSNSTHLTELDLSLNNLEDSGVKLLSDGLKDPHCKLEILRLSDCGVTVEGCADLASALRSNSTHLRELDLTLNNLEDSGVNLLSAGLKDPHCKLEKLRLSDCGFTDEGCADLASALRSNSTHLTELDLSLNNFGDSGVKLLSDGLKDPHCKLEKLRLSYCRVRAEGGVALASALRSNPEHLRELDLSENKLGNSGVKMLSELKNDSRYKLDTLKF", "length": 1375 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCJ8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12-like isoform X1", "gene_name": "si:dkeyp-77c4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKEEHLPNFREKTPPSAQSVRSGSCVSSSVSLKSDWSKRDPPNFREKTPSSAKSSVHQKRAEAEPSCVSMKSDWSMNRPITFRSKITQPAISVDRDDQTGHLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSAQKFILDWAEEKDHQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCALTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQIHMRKQKYEERDPEKLLQSNRGVILKLAEVAFSQLMKGNVMFHEEDLTESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVLYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESTESIRRITQHIKDKIKRDKRLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDELDFNKLNTSAEGRRRLTAAVRNCRRALLQGCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLQWCKPTVQSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLVMCNLTVQCCESLSSALQSSNYVLRELDLSNNDLQDSGVKKLSDGLKSPNCKLETLRLVMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKRNCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKWVCFLTLDPNTAHTQLILSEENREVKRVRENQPYPYHPDRFDVHRQVLCRESVCGRCYWEIDWSGDVGVCISVSYKSIRRKGRGVECWFGYNAQSWSLICSSSRFSFRHNHTDTDLPVEPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFTVYSGSSVKLS", "length": 1235 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCK2-1", "protein_name": "Uncharacterized protein si:dkey-26m3.3 isoform X1", "gene_name": "si:dkey-26m3.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGYVFVLSSLCPVFILLQFLLEFLLEIKLFRSIMGNTHAAGDQDLSTECSSVHQKRAEAEPSCVSMKSDASMGVPITFKSENTGPAVSSVHQKRAEAELSCVSMKSDASMNPPIEFKSGNTGPAVSVDRDGQTGDLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEQIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKDNQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPKLEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTEPSSVAVLMRSLLKGDLLPSALIWITSRPAAAHQIPSTYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLDSNQRLFQDLLTHTEESSENIRRITQYIKDEIKRGKHLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELTPAHCSTISYMIEMSEEPLDELDSNKFNTSDVGRRRLIAAVRNCRRALLQRCELTVQCCESLSSALQSSNCVLRELDLSNNDLQDSAVKLLSDGLKSQHCKLETLRLMTCKLTADSCESLSSALQSSNCVLRELDLSNNDLPDSGVKLLSDGLKSQHCKLETLRLQWCKLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLAMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKTVDCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKYVCFLTLDPNTANTRLILSEENREVKHVRENQPYPDHPDRFDGVYQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGVECWFGSNAQSWSLSCSSSNFSFRHNNTRTDLPVKALNRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRIYPGSSVKLS", "length": 1239 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCL0-1", "protein_name": "Uncharacterized protein si:dkey-165o8.1 isoform X1", "gene_name": "si:dkey-165o8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDQSKDHPPYFREETPSSAESVEYESADPGDETHRRHKSFTDNLQSIFQNLESKIIRFLKNELEKFKKILQEENRKEFIKEFIENRSIITEAALDLTLFFLREMKQDQAADTLQDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNKIYTDLYITQGASEQLNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCGDVSSAVSLDVLLTNLIMGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILRLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLDRNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLDIDKKRGWFLIQISKNKSMIDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQFCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKCRTTHTQTHTHTHTHIHTHTHTHTHIHTHTHTHTHTHTRAHTHTHTRGLQQDRANVGPHTYTHTHTHTHTYTYTHTHTHTHTHTHTHTRITAGPRKCRTTHTHTHTYTHTHTHTITHTHLHIHTHTCTHTHTCAHTHTHIHTHTLTHTRTYTHTHTHTLPLTHTHTHTLSHTHTHTHTNIHTHSLTHTNIHTHSLTHTNKHTHSLSHAYTHACMHALSHLHTHTHALTHTHTHTHTHSLTHTHICTHKHTHTLSHSHKHSHTHTHTHTHTHTHTQARAHLHKHTLSHTHTHIHIYTHTYKHTHILSHTHAHTHTHTQARALTQTYSLTHTHTHTHKHTLSHTHTHIHHTHTQIHIHSHKTHTHARTHTLSLSLTHTHTHTHTHTHTHTHTHTHTHTQLWL", "length": 1266 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JD10-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch211-203c5.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVGYDTECSVCVVCSRMLVCVCVVHLRCSMAEERVKDSLSEKHSVRSGSCVSSSVSLKSDWSKGNPPQFSGESPSSAQSVEYESADSGDETHRRHKSFTDNLQSIFQNLESKMIRFLKNQLEKFKKILQEENRQEFVKEFNENRSIMTEAALDLTLFFLREIKQDQAADTLQDELLYINQLKCSLKKKYQRVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCHDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESSKTLTQMYTHFLRFQIQQSRKKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDRDKKHGLFLQIGKNKGVTDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKKKIIAYIKQKLKGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGRLSSARLSPAQWSALVFVLLTSEEELEEFELHKFQRSDECLIRLSAVIKTSKRALLQSCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPHKYVCFLTLDPNTAHTRLILSEENREVKRVRENQPYPDHPDRFDGYVYPQVLCRESVCGRCYWEIDWSGDDGVFISVSYKSIRRKGGGVECWFGCNAQSWSLLCDSSSFSFRHNNTLTDLPVEALSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCAGFGFSSGSSVKLS", "length": 1073 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z7N0-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Dmel\\CG8197", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCDVLLPCEYNPKECPSPAAEKSRLFTILLLYCWQREYDKRPYRQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLRRPQLSVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPREFFVMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANRLLGMSLSLDTEKISSVLSSLLMQNTLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLAMKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISYTYDEALQDYRVVPWR", "length": 387 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZAD9-1", "protein_name": "NLR family, pyrin domain containing 9", "gene_name": "Nlrp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDTSGYGLLKHLRKLSDGEFWSFKELLRKEPEKFKLKPISWMKIENASKEELVMLLNTHYPKQAWDMALSLFLQVNREDLSIMAQKKRRYKQTKYKKFMKTTFQSIWTLESNICIPDRSYHLIVEHQYRKLQNIFDSESEPVTAVVTGPTGEGKTVFLRKAMLDWASGILWQNRFQYVFFFSVLSLNNTTELSLAELISSKLPESSETLNDILSDPKKILFILDGFDYLKFDLELRTNLCNDWRKILPTQIILSSLLQKIMLPESSLLLELGHISLPKIFPLLQYPRDITIQGFSERCLKTYFISFFNTEKGIEVFENLKSNQMLKLCSNPYLCWMFCSCLKWQFDREEEAYFQAKTDSVFFTSFMVSAFKSAYASNPPKQNRAQLKSLCTLAVEGMWKQLFVFDSEDLRRNGISESDKAVWLRMKFLQNHDNHIVFYHPTLQLYFASMFYFLKQDKDTHVPVIGSIPQLLRKIYARDHTQWLQIGIFLFGLATEQVASLLKPYFGFIQHRDVRQEVMRYLKSLSQRECCEKLERPQNLFACLRDNKEEKFVREVVDLFEEITVDITNSHVLSIIANHLQKSSKLKKLHLHIQKRVFLEIHDPEYSDSETFTQDKKNAAEYWKKLCHIFVNLHVLDLDSCNFNKQVIEELCNVLSPSPKIPLMAFKLESLLCSFMTNFGDGSLFHTLLQLPHLKYLNLYGTNLSNSRIENLCSALRRSTCKVEELLHSEMSFPLSTDFIVSHKFGLGKCDISSEACGIIATSLMNSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLETLMLSYCCLTFIACGHLYEALVSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCILKELWLSGCFLTSECCEEISAVLTCNNNLKTLKLGNNDIEDTGVKHLCEALSHPNCKLECLGLDLCKFTSDCCEDLASALTTCKTLNSLNLDWKTLEHSGVVALCEALNHKKCNLKMLGLDKSAFSVESQTLLQAVEKKNNNLSILHYPWVEEERKKRGVRLVWNSKN", "length": 1022 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZP31-1", "protein_name": "NLR family, pyrin domain containing 4", "gene_name": "Nlrp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEILQLRLKQISWTKVKKASREDLANLLLKHYEEKQAWDMTFKIFQKMNRKDLIERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKAQDLFKQKFTQDDCDRFENLLVSKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGIVFQNKFSYIFYFCCQDVKQLKRASLAELISREWPNASAPTAEILSQPEKLLFIIDSLEVMECNMSERESELCDNCTEKQPVSLLLSSLLRRKMLPESSFLISATPETFEKMEDRIECTNVKIITGFNENNIKMYFRSLFQDKNRTLEAFSLVRENEQLFNVCQVPVLCWMVATCIKKEIEKGRDPVFICRRTTSLYTTHIFNLFTPQNAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFSEEALRRNGILDSDIPTLLDRRILERSKESESCYIFLHPSLQEVCAAVFYLLKSHLDHPSQDVKSVEALLFTFLKKAKVQWIFLGCFLFGLLHESEQEKLEMFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEAFLMQAMNCMEQINFVAKDYSDVIVAAYCLKHCSTLKKLSFSTQNILSEEQEHSYTEKLLICWHHMCSVLISSKDIHVLQVKDTNLNETAFWVLYNHLKYPSCTLKVLVVNNVTFLCDNHLFFELIQNQRLQHLNLSLTFLSHSDVKLLCDVLNQAECNIEKLMIAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLCKALCHPDCILKHLVLANCSLSEQCWDYLSEVVRRNKTLSHLDISSNDLKDEGLKVLCGALTLPDSGLISLSVRHCLITTSGCQDLAEVLRHNQNLRSLQVSNNKIEDAGVKLLCDAIKQPNCHLENIGLEACELTGACCKDLASAFVHCKTLWGINLLENALDHSGLVVLFEALKQQKCTLHVLGLRITDFDKETQEFLIAEEEKNPYLSILSNV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZUH1-1", "protein_name": "NLR family, pyrin domain containing 4A", "gene_name": "Nlrp4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLGLKQVSWTEVKKASREDLASLLLKHYEEKQAWDMTFNFFQKINRKDLIKRAKREIDGYPKLYRAHLKTKLTHDSSRIFNINIQDFLKEKFTKDDHDRFETLLQSKGTESKPQVVVLSGVAGIGKTLMLKRLMLAWIEGLVFPYKFSYIFYFCCQEVKQLKTASLAELISREWPDPSAPIEEILSEPEKLLFIIDSLEGIECDLFKCDSELCDNCMEKQPVNILLSSLLRKKMLLEASLLISTTPETFEKMEDRIEYTHVKIITGLNESDIKMCFHRLFQDRNRAQEAFSLVRENEQMLTICQVPVLCWMVATCLKTEIEKGRNLVSTCRRTTSLYTTYIFNLFIPQSAHSPSKKSQDQLQGLCSLAAEGIWTDTFVFTEEALRRNGILDSDIPTLLDIGMLGKMGKFENCYIFLHPSLQEACAAIFYLLKSHGDHPIEDVKSVEALLFTFLKKAKVQWILGGRFIFGLLHESEQKKLEAFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEDFLMEAMNYMEQINFVAKDYSDVIVAAYCLKHCYTLKKLSFSTQNILNEEHEHSCMENLLTCWRHICSVLINSKDIQELQIKDTNLNEPAFSVLYNSLKYCNDTLKVLVENNVFFLCEKYLFFELIQNCNLQHLNLNLTFLSHSDVKLLCDVLNQAECNIEKLEVAACNLSPDDCKMFASILMSSKTLKQLNLSSNILGKGISSLCKSLCHPDCILEHLVLAKCSLSDQCWDYLSDGIRQNKTLNHLDISSNDLKDEGLKVLCRALALPNSVLKSLCLRHCLITTSGCQDLAEVLRNNQNLTSLQISYNKIEDAGVKLLCDAIKQPNCHLEDLGLEACELTGACCEDLASTFTQCRTLWGINLLNNTLDYTGLVVLCEALRQQKCTPHVLGLRITDFDNETQAFLVAEQEKNPDLSILSGV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A1P8-1", "protein_name": "NLR family, pyrin domain containing 4B", "gene_name": "Nlrp4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLFSDFGFMWYWKELNKVEFMKFKELLILEILQMGLKQISWTEVKNASREDLAILLVKYCEGKQAWDTTFKVLQKISRHDLTERATGEIAAHANIYRAHLKKKLTRDCSRKFSISIQNFFQDEYDHLENLLIPKVTEEKPQLVFLKGIAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCQDVKQLKTTSLTELISREWPSSSAPIEEILSQPEKLLFIIDSLEGMEWDFTKQESELCDNCLEKQPVNVLLSSLLKKKILPESSLLISATFETFEELKDWIEYTNVRTITGFKESNIKMYFHSLFQDRNRALEAFSFVRENEQLFTLCQAPVICCMVATCLKNEIEKGKDPVSICRRTTSLYTTHIFNLFIPPNVQYPSKKSQDQLQGLCFLAVEGMWTDISVFSEETLRRNGILDSDIPTLLDIGILEQSRESQNSYIFFHPSVQEFCAAMFYLLQTHMNHPSPDVLHVEKLLFSFLKEVNTQWIFLGRFIFGLLNELEHEKLEAFFGYQLSQQLKQELFEWLELLLDPEVKVNTMKFFYCLFEMEEEVFVQSAMNCREEIDVVAKDYYDFIVAAYCLNHGSALRDLSISTQNVLNEKLNQRYMENLLMLWHNICSVFARNKDIHILQMKDTIFNEPVFQILYNYLKNSSCILEVLVANDVSFLCDKYLFFDLIQSYNLELLDLSGTFLSHSDVVILCNILNKAEYKIQELELANCSLSEQSWKYISDVLCQNKTLRHLDISSNDLKDEGLKVLCKALTLPDSVLLTLSVKACFITTVGCQYLAEVLRNNHKLMFLTLSENKLEDSGVKLLCDAIKHPRCQLAQLDLEACELTGACCEDLASTFTQCKTLGWINLVKNALDFNGLVVLCKALKQKTSNLKELRLRITDFDNKSQTFLLSEEKGNKFLNIENDE", "length": 918 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A523-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWNDACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGRTKMWDRPMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEEEEKRGSQPLDQVQCVFPDPHVACSSRLVNCCLTSSFCRGLFSSLSTNQSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSSQKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTNQNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNCETKRTLEALQEEKPELTVVFEISW", "length": 1035 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FA88-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "nlrc11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYCNYNMDNTRSSRDEDIYSCTSRESEEVLSNTSYWSLPSYFRHRKFHRSSVHEKISDSSESSRVSLKSDWSMNPPPLLGEERKSSNLNMSSLVSVRSDWSMDPPPLLRAKGKSAVSSGVSDNIDWLVCSPYLRVERKSSALRHKLSLLKKFQCLYEGTAVQGKPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLIKDKKFSLVSLLQTFFTREIHLDMIQNSAVIFIFDGLDECRLPFNFSRNEILLDVTKETSVDVLLTNLIVGNLLPYALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILRLGKLAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLLFTNHNINVFEQMTKSFEGTPLNKSDLQSLTLNMELFEISEPVLTDVAAMCEMDWRVVNEISALHCKAVDEVLQNKNGHLDLFLRFLLGLSVECNQILLQRLTKQRRHLYNDNKTVEYIKKKIRTINSPEKSISLFHCLNELGDHSLVEEIQQYLTSGKIKEFKLSSSQWSAVAFVLLTSEKKLEEFWLKEFVGAETKADHVLQKLLPVVKESRKAELSKCGLTEECCAALASALRSKLSHVRELDLSGNKLGDSGIENLSTGLENLHCKLEILRLRSCGITAKGCTALASALRSNPEQIRQLDLSENNIRDWGVKHLFTELKNPDCKLEILGLRNCGITIEGCAALTSALIINPSHLRELDISRNSLGDTGQELLTSLLNSQHHKLEILLLHKFPMTFTSLPSSHSPEMFPQRFRTHNLKE", "length": 966 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q5R7-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSTARDGLYRLSTYLEELEAGELKKFKLFLGIAEDLSQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGEDLVRVTPNNGLCLFESQSACPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPEPPHTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGPWCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTPRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFAAMYCALNGREAVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWSISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQVVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGSAYSTGMEDDPPEPSGVQTQSTYLQERNMLPDVYSAYLSAAVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISGSACQDLAAAVIANRNLIRLDLSDNSIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLSNNSYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVNTCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGISQTLHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFGMDLNKKTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M918-1", "protein_name": "NLR family, pyrin domain containing 14", "gene_name": "Nlrp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTEDEEMEDQLSKEEIVSEDKEFDYRTIIKENFFIIWDKTSLLGESATLNCVTTHKDQKLLEHIFDVNIQTSKSPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLSGREISQEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFALCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMTCQTSTALFTYYICSLFPRIAGSSVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQDTECENCYTFTHLQVQEYFAALFYLLRENPEEKDHPLEPFENVHLLLESNHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLTISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVKVDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDPTAEICLEDAAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLNSCYDFSFLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQSNRSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTKTKRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNNKSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNNSNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNNQSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCPNTESGCWWQYF", "length": 990 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RA38-1", "protein_name": "NLR family pyrin domain containing 2", "gene_name": "Nlrp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHSDQLGFNLKDVLKKLDKTELNNFKSTLKSCSLPQTMKQISKLTMDLANGAQLAEILTDYCPNDWVKRVTFKILEEINRADLAELVMKQVEEAASKASEEKVSSKPREPLKTSLFPQDFVQGDERPEHKHKKEWRNMYTEKWKKNFWPKCNKEIYVDTESYRTLLTLCNPKIEMPFAYTIVLHGPPGSGKTTMARRLMLEWSESKQAQSFSCAFYISCRKLNNSKPCTFAHLLSMNNPSWRYYMIRRLVLSEQFLFVVDGFDELTFPAGALLRDICGDWNTVKPVEVLLSSLLMRKMEPHSTLLVTTQTQSLHQIYLMVDQPVLVETQGFLEPEKQEYFQQYFEDEEGEEEGEGEGKALRALKEVKCNEALFQMASLPAACGIFCLCLELGMKKGEDLALTCQTYTSMFLNFLCRVFLQEACDGHLNKQLQILFKKICILAADSLLEQVPILCEEDFLKLKLNLNKLHPVVYRCIFLEDSSCTNCLSFICLSIQQLLAAIIFVQELGQESKDVSKYSIQKMLSREARLKNPNLSGVLPFVFSLLNKTHIQELETIFGCQISMGVKRKFLECELGENKPFLLLMDLQEIFSCLYESQEEEFVKEAMALFGEVSLHLKTNMDLVHASFCLKNSQNLQTMFLKVEKAVFPENFATLESTAEDQRFQDKKCMLTLWTDFCDTFHSNEKLAFLEIHESFLNSSSLEILCEKLSSAPCHLQKVVLKNISPDDAYEKLCLIFCGYETISHLTLQGGKLDSMLHSLCKVVKNPACNLKFLSLGSCSTTAQKWDDFFPALKANQSLISLDLTDNNLLDKGVRLLCNTWKQSKCILQRVSLENCHLTEVCCKDLSSVLMVSQTLTHLSLAKNELGDNGVKKLCESLSFPKCKLQTLVLWSCNITSNGCHYLSKMLGQAPSLKHLDLGLNRIGTTGAKFLCEALKSPRSNLKSLWLCGCSIIPTNCKDFSEILRSNKSLNTLDLSQNVMGTDAVKIFCESLKLQICPLQTLRLKFDEANPSIQKLIQEMKESHPQLSITSDQVDPKKKSHSFPHFIF", "length": 1048 }, "evidence": [ { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13489-1", "protein_name": "Ribonuclease inhibitor", "gene_name": "RNH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEARCKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGAGCGVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRDLCGIVASKASLRELALGSNKLGDVGMAELCPGLLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEGARLLCETLLEPGCQLESLWVKSCSFTAACCSHFSSVLAQNRFLLELQISNNRLEDAGVRELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAATLLANHSLRELDLSNNCLGDAGILQLVESVRQPGCLLEQLVLYDIYWSEEMEDRLQALEKDKPSLRVIS", "length": 461 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59044-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 6", "gene_name": "NLRP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGPDGRSIPWGRLERADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSEYKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQPQRLLFILDGADELPALGGPEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRLQGRLCSPQCAEVRGFSDKDKKKYFYKYFRDERRAERAYRFVKENETLFALCFVPFVCWIVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAREGVLGRRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAALSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLVLTTRFLFGLLSAERMRDIERHFGCMVSERVKQEALRWVQGQGQGCPGVAPEVTEGAKGLEDTEEPEEEEEGEEPNYPLELLYCLYETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLISCRLVAAQEKKKKSLGKRLQASLGGGSSSQGTTKQLPASLLHPLFQAMTDPLCHLSSLTLSHCKLPDAVCRDLSEALRAAPALTELGLLHNRLSEAGLRMLSEGLAWPQCRVQTVRVQLPDPQRGLQYLVGMLRQSPALTTLDLSGCQLPAPMVTYLCAVLQHQGCGLQTLSLASVELSEQSLQELQAVKRAKPDLVITHPALDGHPQPPKELISTF", "length": 892 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59045-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 11", "gene_name": "NLRP11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESDSTDFDLLWYLENLSDKEFQSFKKYLARKILDFKLPQFPLIQMTKEELANVLPISYEGQYIWNMLFSIFSMMRKEDLCRKIIGRRNRNQEACKAVMRRKFMLQWESHTFGKFHYKFFRDVSSDVFYILQLAYDSTSYYSANNLNVFLMGERASGKTIVINLAVLRWIKGEMWQNMISYVVHLTAHEINQMTNSSLAELIAKDWPDGQAPIADILSDPKKLLFILEDLDNIRFELNVNESALCSNSTQKVPIPVLLVSLLKRKMAPGCWFLISSRPTRGNNVKTFLKEVDCCTTLQLSNGKREIYFNSFFKDRQRASAALQLVHEDEILVGLCRVAILCWITCTVLKRQMDKGRDFQLCCQTPTDLHAHFLADALTSEAGLTANQYHLGLLKRLCLLAAGGLFLSTLNFSGEDLRCVGFTEADVSVLQAANILLPSNTHKDRYKFIHLNVQEFCTAIAFLMAVPNYLIPSGSREYKEKREQYSDFNQVFTFIFGLLNANRRKILETSFGYQLPMVDSFKWYSVGYMKHLDRDPEKLTHHMPLFYCLYENREEEFVKTIVDALMEVTVYLQSDKDMMVSLYCLDYCCHLRTLKLSVQRIFQNKEPLIRPTASQMKSLVYWREICSLFYTMESLRELHIFDNDLNGISERILSKALEHSSCKLRTLKLSYVSTASGFEDLLKALARNRSLTYLSINCTSISLNMFSLLHDILHEPTCQISHLSLMKCDLRASECEEIASLLISGGSLRKLTLSSNPLRSDGMNILCDALLHPNCTLISLVLVFCCLTENCCSALGRVLLFSPTLRQLDLCVNRLKNYGVLHVTFPLLFPTCQLEELHLSGCFFSSDICQYIAIVIATNEKLRSLEIGSNKIEDAGMQLLCGGLRHPNCMLVNIGLEECMLTSACCRSLASVLTTNKTLERLNLLQNHLGNDGVAKLLESLISPDCVLKVVGLPLTGLNTQTQQLLMTVKERKPSLIFLSETWSLKEGREIGVTPASQPGSIIPNSNLDYMFFKFPRMSAAMRTSNTASRQPL", "length": 1033 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59046-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "NLRP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQSTCLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELKPSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEGEGGAGPDQDVTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSAGAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIANKNLTRMDLSGNGVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC", "length": 1061 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 5", "gene_name": "NLRP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVAGGLELGAAALLSASPRALVTLSTGPTCSILPKNPLFPQNLSSQPCIKMEGDKSLTFSSYGLQWCLYELDKEEFQTFKELLKKKSSESTTCSIPQFEIENANVECLALLLHEYYGASLAWATSISIFENMNLRTLSEKARDDMKRHSPEDPEATMTDQGPSKEKVPGISQAVQQDSATAAETKEQEISQAMEQEGATAAETEEQEISQAMEQEGATAAETEEQGHGGDTWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDSDRWGFRPRTVVLHGKSGIGKSALARRIVLCWAQGGLYQGMFSYVFFLPVREMQRKKESSVTEFISREWPDSQAPVTEIMSRPERLLFIIDGFDDLGSVLNNDTKLCKDWAEKQPPFTLIRSLLRKVLLPESFLIVTVRDVGTEKLKSEVVSPRYLLVRGISGEQRIHLLLERGIGEHQKTQGLRAIMNNRELLDQCQVPAVGSLICVALQLQDVVGESVAPFNQTLTGLHAAFVFHQLTPRGVVRRCLNLEERVVLKRFCRMAVEGVWNRKSVFDGDDLMVQGLGESELRALFHMNILLPDSHCEEYYTFFHLSLQDFCAALYYVLEGLEIEPALCPLYVEKTKRSMELKQAGFHIHSLWMKRFLFGLVSEDVRRPLEVLLGCPVPLGVKQKLLHWVSLLGQQPNATTPGDTLDAFHCLFETQDKEFVRLALNSFQEVWLPINQNLDLIASSFCLQHCPYLRKIRVDVKGIFPRDESAEACPVVPLWMRDKTLIEEQWEDFCSMLGTHPHLRQLDLGSSILTERAMKTLCAKLRHPTCKIQTLMFRNAQITPGVQHLWRIVMANRNLRSLNLGGTHLKEEDVRMACEALKHPKCLLESLRLDCCGLTHACYLKISQILTTSPSLKSLSLAGNKVTDQGVMPLSDALRVSQCALQKLILEDCGITATGCQSLASALVSNRSLTHLCLSNNSLGNEGVNLLCRSMRLPHCSLQRLMLNQCHLDTAGCGFLALALMGNSWLTHLSLSMNPVEDNGVKLLCEVMREPSCHLQDLELVKCHLTAACCESLSCVISRSRHLKSLDLTDNALGDGGVAALCEGLKQKNSVLARLGLKACGLTSDCCEALSLALSCNRHLTSLNLVQNNFSPKGMMKLCSAFACPTSNLQIIGLWKWQYPVQIRKLLEEVQLLKPRVVIDGSWHSFDEDDRYWWKN", "length": 1200 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TKR3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4C", "gene_name": "Nlrp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLRLKQISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRKDLMERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKVQDFSKQKFTQDDYDRFENFLISKVTAKKPHMVFLQGAAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPKTSAPIEDILSQPEKLLFVIDNLEVMECDMSERESELCDTCTEKQPVRILLSSLLRRKMLPKSSFLISATPETFEKMEGRVECTNVKIVTGFNESNIKMYFRSLFQDKTKTQEIFSLVKENQQLFTVCQVPVLCWMVATCLKKEIEKGRDLVSVCRRTTSLYTTHIFNLFIPQSAQYPSKESQAQLQSLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPTLLDVRILEKSKKSEKSYIFLHPSIQEVCAAIFYLLKSHMDHPSQDVKSIEALIFTFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQVDGMKLFYCLFEMDDEAFLAQAMNCMEQINFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNVLSEGQEHSYTEKLLMCWHHMCSVLISSKDIYILQVKNTNLNETASLVLYSHLMYPSCTLKALVVNNVTFLCDNRLFFELIQNQCLQHLDLNLTFLSHGDVKLLCDVLSQEECNIEKLMVAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLVNCSLSEQCWDYLSEVLRRNKTLNHLDISSNDLKDEGLKVLCGALSLPDSVLKSLSVRYCLITTSGCQDLAEVLRKNQNLRNLQVSNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASAFTHCKTLWGINLQENALDHSGLIVLFEALKQQQCTLHVLGLRITDFDKETQELLMAEEEKNPHLSILSSV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X03-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9A", "gene_name": "Nlrp9a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDSSGYGLLQYLQKLSDEEFQRFKEHLRKEPEKFKLKPISWTKIKNTSKEDLVMQLYTHYPGKAWDMVLSLFLQVNREDLSTMAQTERRDKQTKYKEFMKNTFQHIWTMETNTYIPDRSYHEFIEVQYRALQDIFDCESEPVTVVVSGSRGGGKTTFLRKAMLDWASRNLLQNRFQYVFHFSVFSLNNITELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKKLPIQIVLSSLLQKIMLPECSLLLELGNASLSNIIPLLQYPREIIMSGFSEQTIEIYCVSFFNTQTGVEIFKNLKSIKPLFNLCRCPHLCWMICSTIKWQYERREVASRFGRTLGLLYTIFMVSAFKSTYARNPSKQNRARIRTLCTLAVEGMWKQVYVFDSDDLRRNGISESDKKVWLRMKFLQNQGSNIVFYHSTLQWYFAVLFYFLQYKDTRHPVIGNLAQLLGEIYAHKQNQWFHTRILLFGMATEQVNSLLEPCFGCISSKEVRQEIIRYIKSLSQQECNEKLVVHPQNLFFCILDNQEERFVRQLMDRFEEMTVDISDVDDMSATPYCLHRAPKVKNLHLHIQKRVFLEIHDPEYGDLELFKLGQKCSFTTNFGDGLLFCTFLHLPHLKYMNLYGTNLSNDAVERLCSALKFSTCGVEELLLGKCDISSEACGIIAASLINSEVKHLSLVENPLKNKGVMSLCEMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNEHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCYLTSECCEEISAVLTCNTNLKTLKLGNNNIQDTGVKRLCEALCHPNCEMQCLGLDMCDFTSDCCEDLALVLTTCNTLKSLNLDWNAFDHSGLEMLCKALNHKACNLEVLGLDKSLFSEESQTLLQAVEKKNKNLKVLHFPWLKEELEKRGVRLVWNSKN", "length": 949 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X05-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4F", "gene_name": "Nlrp4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFISDFGLIWYLRELNKKEFMKFKDFLIQEILELKLKQVSSTKVKKASREDLANLLLKCGENQAWDMTFRILQKINRKDLTERATGAIVGNPNLYRDHLKKKLTHDCPKKFNVRIQDFIKETFIQNDXDAFENLLISKGTERKPHMVFLKGMAGVGKTLMLKNLMLAWSKGLVFQNKFSYAFYFCCQDVKQLKTASLAELISREWPSPSAPIEEILSQPEKLLFIIDSLEGMEWDLTKQESELCDDCMEKQPVSTLLSSLLRRKMLPESSLLLSTTPETFEKMEDRIQCTDVKTATAFDERSMKIYFHRLFQDRKRAQEAFSLVRENKQLFTICQVPLLCWMVATCLKEEIEKGGDPVSLCRRTTSLYTTHIFSLFIPQSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFGKEALRRNGIFDSDIPTLLDIGMLGKIREFENSYIFLHPSVQEVCAAIFYMLKRHVEHPSQDVKNIETVLFMFLKKVKTQWIFLGCFIFGLLQKSEQEKLGVFFGHRLSKNIHHKLYQCLETLSGNAELQEQIDGMRLFSCLFEMEDEAFLVKAMNCMQQINFVAKNYSDFIVAAYCLKHCSTLKKLSFSTENVLNEGDQSYMEELLICWNNMCSVFVRSKDIQELRIKDTNFNEPAIRVLYESLKYPSFTLNKLVANNVSFGDNHVLFELIQNSSLQYLDLSCSFLSHNEVKLLCDILNQAECNIEKLMIAHCKLSPDDCKIFGSILMSSKSLKVLNLASNNLNQGISSLCKALCHPHCTLEYLVPRSNHCIVNFLLKLSCCGITERGCQDLAEVLKNNQNLKYLHVSYNKLKDTGVMLLCDAIKHPNCHLKDLQLEACEITDASNEELCYAFMQCETLQTLNLMGNAFEVSRMVFFPRKSELMLFIFLHLSRLWITDFDNEFQAFLLSVKKKNHFLTIRGSVEADGEKKGGDSDARTMGELSNEI", "length": 959 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X19-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4E", "gene_name": "Nlrp4e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKELLQQEILQLGLKHISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRQDLMERAGREIAGHSKLYQVHLKKKLTHDYARKFNIKDQDSLKQKFTQDDCDHFENLLISKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPNASAPIEEILSQPEKLLFVIDNLEVMECDMSEWESELCDDCMEKQPVNILMSSLLRRKMLPESSFLVSATPETFEKIEDRIECTNVKMMAGFNESSIKVYFYSLFQDRNRTQEIFSLVRENEQLFSVCQVPVLCWMVATCLKKEIEKGRDPVSICRRITSLYTTYIFNLFIPHSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFAEEALRRNGIMDSDISTLLDVRILEKSKESEKSYIFLHPSIQEVCAAIFHLLKSHVDHPSQDVKSIEALIFTFLKKVKIQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNKELQEQIDGMKLFYCLFEMDDEAFLPQVMNCMEQIKFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNILSEGQEHSYTEKLLICWHHVCSVLTSSKDIHVLQVKDTNFNERAFLVLYSHLKYPSCILKVLEVNNVTLLCDNRLLFELIQNQRLQLLNLSLTFLSHNDVKLLCDVLNQAECNIEKLMVADCNLSPDDCKVFVSVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLAKCSLSEECWHYLSEVLRRNKTLTHLDISFNDLKDEGLKVLCGALTLPDSVLISLSVRYCLITTSGCQDLAEVLRNNQNLRNLQISNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASSFTHCKTLLGINLQENALDHSGLVALFEAMKQQQCTVNLRGLRITDFDKETQEFLMAEKEKNPYLSI", "length": 978 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X22-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9B", "gene_name": "Nlrp9b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSSGYGLLKLLQKLSDEEFQRFKELLREEPEKFKLKPISWTKIENSSKESLVTLLNTHYPGQAWNMMLSLFLQVNREDLSIMAQKKKRHKQTKYKKFMKTTFERIWTLETNTHIPDRNYHLIVEVQYKALQEIFDSESEPVTAIVAGTTGEGKTTFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKRLPTQIVLSSLLQKIMLPGCSLLLELGQISVPKIRHLLKYPRVITMQGFSERSVEFYCMSFFDNQRGIEVAENLRNNEVLHLCSNPYLCWMFCSCLKWQFDREEEGYFKAKTDAAFFTNFMVSAFKSTYAHSPSKQNRARLKTLCTLAVEGMWKELFVFDSEDLRRNGISESDKAVWLKMQFLQTHGNHTVFYHPTLQSYFAAMFYFLKQDKDICVPVIGSIPQLLGNMYARGQTQWLQLGTFLFGLINEQVAALLQPCFGFIQPIYVRQEIICYFKCLGQQECNEKLERSQTLFSCLRDSQEERFVRQVVDLLEEITVDISSSDVLSVTAYALQKSSKLKKLHLHIQKTVFSEIYCPDHCKTRTSIGKRRNTAEYWKTLCGIFCNLYVLDLDSCQFNKRAIQDLCNSMSPTPTVPLTAFKLQSLSCSFMADFGDGSLFHTLLQLPHLKYLNLYGTYLSMDVTEKLCAALRCSACRVEELLLGKCGISSKACGIIAISLINSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLQSLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCFLTSQCCEEISAVLICNRNLKTLKLGNNNIQDTGVRQLCEALSHPNCNLECLGLDLCEFTSDCCKDLALALTTCKTLNSLNLDWKTLDHSGLVVLCEALNHKRCNLKMLGLDKSAFSEESQTLLQDVEKKNNNLNILHHPWFEAERNKRGTRLVWNSRN", "length": 1003 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6B966-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "Nlrp14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTEDDEMEYEASKEETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITPKDQNLLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLNGKEISQVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFALCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVGCVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQDTEYENCYMFTHLHVQEFFAALFYLLRENLEEQDYPSEPFENLYLLLESNHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVRVDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLDTAEMCLEGAAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLNGCQDFTFLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTKSKRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHNRSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNNSNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNNKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECPNTESGCWWNYF", "length": 993 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTR0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9", "gene_name": "NLRP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESFFSDFGLLWYLKELRKEEFWKFKELLKQPLEKFELKPIPWAELKKASKEDVAKLLDKHYPGKQAWEVTLNLFLQINRKDLWTKAQEEMRNKLNPYRKHMKETFQLIWEKETCLHVPEHFYKETMKNEYKELNDAYTAAARRHTVVLEGPDGIGKTTLLRKVMLDWAEGNLWKDRFTFVFFLNVCEMNGIAETSLLELLSRDWPESSEKIEDIFSQPERILFIMDGFEQLKFNLQLKADLSDDWRQRQPMPIILSSLLQKKMLPESSLLIALGKLAMQKHYFMLRHPKLIKLLGFSESEKKSYFSYFFGEKSKALKVFNFVRDNGPLFILCHNPFTCWLVCTCVKQRLERGEDLEINSQNTTYLYASFLTTVFKAGSQSFPPKVNRARLKSLCALAAEGIWTYTFVFSHGDLRRNGLSESEGVMWVGMRLLQRRGDCFAFMHLCIQEFCAAMFYLLKRPKDDPNPAIGSITQLVRASVVQPQTLLTQVGIFMFGISTEEIVSMLETSFGFPLSKDLKQEITQCLESLSQCEADREAIAFQELFIGLFETQEKEFVTKVMNFFEEVFIYIGNIEHLVIASFCLKHCQHLTTLRMCVENIFPDDSGCISDYNEKLVYWRELCSMFITNKNFQILDMENTSLDDPSLAILCKALAQPVCKLRKLIFTSVYFGHDSELFKAVLHNPHLKLLSLYGTSLSQSDIRHLCETLKHPMCKIEELILGKCDISSEVCEDIASVLACNSKLKHLSLVENPLRDEGMTLLCEALKHSHCALERLMLMYCCLTSVSCDSISEVLLCSKSLSLLDLGSNALEDNGVASLCAALKHPGCSIRELWLMGCFLTSDSCKDIAAVLICNGKLKTLKLGHNEIGDTGVRQLCAALQHPHCKLECLGLQTCPITRACCDDIAAALIACKTLRSLNLDWIALDADAVVVLCEALSHPDCALQMLGLHKSGFDEETQKILMSVEEKIPHLTISHGPWIDEEYKIRGVLL", "length": 991 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W24-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "NLRP14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSSSSSFFPDFGLLLYLEELNKEELNTFKLFLKETMEPEHGLTPWNEVKKARREDLANLMKKYYPGEKAWSVSLKIFGKMNLKDLCERAKEEINWSAQTIGPDDAKAGETQEDQEAVLGDGTEYRNRIKEKFCITWDKKSLAGKPEDFHHGIAEKDRKLLEHLFDVDVKTGAQPQIVVLQGAAGVGKTTLVRKAMLDWAEGSLYQQRFKYVFYLNGREINQLKERSFAQLISKDWPSTEGPIEEIMYQPSSLLFIIDSFDELNFAFEEPEFALCEDWTQEHPVSFLMSSLLRKVMLPEASLLVTTRLTTSKRLKQLLKNHHYVELLGMSEDAREEYIYQFFEDKRWAMKVFSSLKSNEMLFSMCQVPLVCWAACTCLKQQMEKGGDVTLTCQTTTALFTCYISSLFTPVDGGSPSLPNQAQLRRLCQVAAKGIWTMTYVFYRENLRRLGLTQSDVSSFMDSNIIQKDAEYENCYVFTHLHVQEFFAAMFYMLKGSWEAGNPSCQPFEDLKSLLQSTSYKDPHLTQMKCFLFGLLNEDRVKQLERTFNCKMSLKIKSKLLQCMEVLGNSDYSPSQLGFLELFHCLYETQDKAFISQAMRCFPKVAINICEKIHLLVSSFCLKHCRCLRTIRLSVTVVFEKKILKTSLPTNTWDGDRITHCWQDLCSVLHTNEHLRELDLYHSNLDKSAMNILHHELRHPNCKLQKLLLKFITFPDGCQDISTSLIHNKNLMHLDLKGSDIGDNGVKSLCEALKHPECKLQTLRLESCNLTVFCCLNISNALIRSQSLIFLNLSTNNLLDDGVQLLCEALRHPKCYLERLSLESCGLTEAGCEYLSLALISNKRLTHLCLADNVLGDGGVKLMSDALQHAQCTLKSLVLRRCHFTSLSSEYLSTSLLHNKSLTHLDLGSNWLQDNGVKLLCDVFRHPSCNLQDLELMGCVLTNACCLDLASVILNNPNLRSLDLGNNDLQDDGVKILCDALRYPNCNIQRLGLEYCGLTSLCCQDLSSALICNKRLIKMNLTQNTLGYEGIVKLYKVLKSPKCKLQVLGLCKEAFDEEAQKLLEAVGVSNPHLIIKPDCNYHNEEDVSWWWCF", "length": 1093 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W25-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 13", "gene_name": "NLRP13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFSVITCPNGGTNQGLLPYLMALDQYQLEEFKLCLEPQQLMDFWSAPQGHFPRIPWANLRAADPLNLSFLLDEHFPKGQAWKVVLGIFQTMNLTSLCEKVRAEMKENVQTQELQDPTQEDLEMLEAAAGNMQTQGCQDPNQEELDELEEETGNVQAQGCQDPNQEEPEMLEEADHRRKYRENMKAELLETWDNISWPKDHVYIRNTSKDEHEELQRLLDPNRTRAQAQTIVLVGRAGVGKTTLAMQAMLHWANGVLFQQRFSYVFYLSCHKIRYMKETTFAELISLDWPDFDAPIEEFMSQPEKLLFIIDGFEEIIISESRSESLDDGSPCTDWYQELPVTKILHSLLKKELVPLATLLITIKTWFVRDLKASLVNPCFVQITGFTGDDLRVYFMRHFDDSSEVEKILQQLRKNETLFHSCSAPMVCWTVCSCLKQPKVRYYDLQSITQTTTSLYAYFFSNLFSTAEVDLADDSWPGQWRALCSLAIEGLWSMNFTFNKEDTEIEGLEVPFIDSLYEFNILQKINDCGGCTTFTHLSFQEFFAAMSFVLEEPREFPPHSTKPQEMKMLLQHVLLDKEAYWTPVVLFFFGLLNKNIARELEDTLHCKISPRVMEELLKWGEELGKAESASLQFHILRLFHCLHESQEEDFTKKMLGRIFEVDLNILEDEELQASSFCLKHCKRLNKLRLSVSSHILERDLEILETSKFDSRMHAWNSICSTLVTNENLHELDLSNSKLHASSVKGLCLALKNPRCKVQKLTCKSVTPEWVLQDLIIALQGNSKLTHLNFSSNKLGMTVPLILKALRHSACNLKYLCLEKCNLSAASCQDLALFLTSIQHVTRLCLGFNRLQDDGIKLLCAALTHPKCALERLELWFCQLAAPACKHLSDALLQNRSLTHLNLSKNSLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTREGCGELANALSHNHNVKILDLGENDLQDDGVKLLCEALKPHRALHTLGLAKCNLTTACCQHLFSVLSSSKSLVNLNLLGNELDTDGVKMLCKALKKSTCRLQKLG", "length": 1043 }, "evidence": [ { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W26-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 10", "gene_name": "NLRP10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGRYNQVLLVAKPSSESPESLACPFPEQELESVTVEALFDSGEKPSLAPSLVVLQGSAGTGKTTLARKMVLDWATGTLYPGRFDYVFYVSCKEVVLLLESKLEQLLFWCCGDNQAPVTEILRQPERLLFILDGFDELQRPFEEKLKKRGLSPKESLLHLLIRRHTLPTCSLLITTRPLALRNLEPLLKQARHVHILGFSEEERARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRVLRSLCSLAAEGIQHQRFLFEEAELRKHNLDGPRLAAFLSSNDYQLGLAIKKFYSFRHISFQDFFHAMSYLVKEDQSRLGKESRREVQRLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQSQNLFSVKSSLSHGPKEEQKCPSVHGQKEGKDNIAGTQKEASTGKGRGTEETPKNTYI", "length": 655 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W28-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 8", "gene_name": "NLRP8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDVNPPSDTPIPFSSSSTHSSHIPPWTFSCYPGSPCENGVMLYMRNVSHEELQRFKQLLLTELSTGTMPITWDQVETASWAEVVHLLIERFPGRRAWDVTSNIFAIMNCDKMCVVVRREINAILPTLEPEDLNVGETQVNLEEGESGKIRRYKSNVMEKFFPIWDITTWPGNQRDFFYQGVHRHEEYLPCLLLPKRPQGRQPKTVAIQGAPGIGKTILAKKVMFEWARNKFYAHKRWCAFYFHCQEVNQTTDQSFSELIEQKWPGSQDLVSKIMSKPDQLLLLLDGFEELTSTLIDRLEDLSEDWRQKLPGSVLLSSLLSKTMLPEATLLIMIRFTSWQTCKPLLKCPSLVTLPGFNTMEKIKYFQMYFGHTEEGDQVLSFAMENTILFSMCRVPVVCWMVCSGLKQQMERGNNLTQSCPNATSVFVRYISSLFPTRAENFSRKIHQAQLEGLCHLAADSMWHRKWVLGKEDLEEAKLDQTGVTAFLGMSILRRIAGEEDHYVFTLVTFQEFFAALFYVLCFPQRLKNFHVLSHVNIQRLIASPRGSKSYLSHMGLFLFGFLNEACASAVEQSFQCKVSFGNKRKLLKVIPLLHKCDPPSPGSGVPQLFYCLHEIREEAFVSQALNDYHKVVLRIGNNKEVQVSAFCLKRCQYLHEVELTVTLNFMNVWKLSSSSHPGSEAPESNGLHRWWQDLCSVFATNDKLEVLTMTNSVLGPPFLKALAAALRHPQCKLQKLLLRRVNSTMLNQDLIGVLTGNQHLRYLEIQHVEVESKAVKLLCRVLRSPRCRLQCLRLEDCLATPRIWTDLGNNLQGNGHLKTLILRKNSLENCGAYYLSVAQLERLSIENCNLTQLTCESLASCLRQSKMLTHLSLAENALKDEGAKHIWNALPHLRCPLQRLVLRKCDLTFNCCQDMISALCKNKTLKSLDLSFNSLKDDGVILLCEALKNPDCTLQILELENCLFTSICCQAMASMLRKNQHLRHLDLSKNAIGVYGILTLCEAFSSQKKREEVIFCIPAWTRITSFSPTPHPPDFTGKSDCLSQINP", "length": 1048 }, "evidence": [ { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BU40-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4A", "gene_name": "Nlrp4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEVLQLGLKQVSWTEVKKASRQDLASLLLKHYEEKPAWDMTFRFFQKINRKDLIERAKREIDGCPKLYRAHMKTKMTHDSSRAFTISIQNFLKEKFTEDDYDCFENLFQSKGTESKPQVVFLSGGAGVGKTLMLKRLMLAWIESPVFLHKFSYIFYFCCREVKQLKTASLAELISREWPGPSAPIEEILSKPEKLLFIIDSLEGMECDLFKWESELCDNCTEKQPVNVLLSSLLRRKMLPESSLLISATPESFEKMENRIEYTHVKIIKGLKERNIKMSFHRLFQDRNRAHEAFSLVRENEQLFTVCQVPVLCWMVATCLKEEIEKGRDPVSICRCTTSLYTTHIFNLFIPQNAHSPSKKSQDQLQGLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPILLDIGMLINIRESEKSYIFLHPSVQEVCAAIFYLLKSHVDHPSQEVKSIEKLMFAFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQIDGMKLFYCLFEMDDDTFLVEAMNCMEQINFVAKDYSDVIVAAHCLKHCFTLKKLSFSTQNVLSGAQEHSYMERLLTAWNHICSVFIISKDIQELRMKDTNLSESAFSVLYNNLKYHNYTLNVLVANNVFFVCEKYLFFELIQNCNLQHLNLSLTILSHSDVKLLCDVLSQAECNIEELVVAACSISSDDCKVFASVLISNKTLKHLNLASNTLDKGIASLCKSLCHPDCILEHLVLANCSLNEKCWDYLSEVLRRNKTLSHLDISSNDLKDEGLKVLCRALTLPDSVLKSLSLRHCLITISGCQDLAEVLRNNQNLVSLQVSNNKLEDTGVKLLCDAIKHPNCHLEDLGLEACELTGACCEDLASTFTQCKTLWAMNLLKNALDYNGLVVLCEALKQQTCATYVLGLQITDFDTETQAFLVAEQEKNPCLRILSSL", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C6J9-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4B", "gene_name": "Nlrp4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLFSDFGFIWYWKELNKIEFMYFKELLIHEILQMGLKQISWTEVKEASREDLAILLVKHCDGNQAWDTTFRVFQMIGRNVITNRATGEIAAHSTIYRAHLKEKLTHDCSRKFNISIQNFFQDEYDHLENLLVPNGTENNPKMVVLQGVAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCHDVKQLQTASLADLISREWPSPSAPMEEILSQPEKLLFIIDSLEGMEWNVTQQDSQLCYNCMEKQPVNVLLSSLLRKKILPESSLLISTSCETFKDLKDWIEYTNVRTITGFKENNINMCFHSLFQDRNIAQEAFSLIRENEQLFTVCQAPVVCYMVATCLKNEIESGKDPVSICRRTTSLYTTHILNLFIPHNAQNPSNNSEDLLDNLCFLAVEGMWTDISVFNEEALRRNGIMDSDIPTLLDIGILEQSRESENSYIFLHPSVQEFCAAMFYLLHSEMDHSCQGVYFIETFLFTFLNKIKKQWVFLGCFFFGLLHETEQEKLEAFFGYHLSKELRRQLFLWLELLLDTLHPDVKKINTMKFFYCLFEMEEEVFVQSAMNCREQIDVVVKGYSDFIVAAYCLSHGSALTDFSISAQNVLNEELGQRGKLLILWHQICSVFLRNKDIKTLRIEDTIFNEPVFKIFYSYLKNSSCILKTLVAYNVSFLCDKRLFLELIQSYNLEELYLRGTFLSHSDVEMLCDILNQAECNIRILDLANCSLCEHSWDYLSDVLRQNKSLRYLNISYNNLKDEGLKALCRALTLPNSALHSLSLEACQLTGACCKDLASTFTRYKCLRRINLAKNSLGFSGLFVLCKAMKDQTCTLYELKLRMADFDSDSQEFLLSEMERNKILSIENGV", "length": 863 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4B8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWNDTCTSHSSMVCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIGRTKMRDSPMSSLKLELLFEPEDGHSEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSDYLQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFFHNSPKEEEEERRGGRPLDQVQCVFPDTHVACSSRLVNCCLTSSFCRGLFSSLSTNRSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSSSQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTNQNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHNHSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNRETKRALEALQEEKPELTIVFEISW", "length": 1033 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WX94-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 7", "gene_name": "NLRP7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQIARGLWILCQALENPNCNLKHLRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATAPPCCDFFC", "length": 980 }, "evidence": [ { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96MN2-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4", "gene_name": "NLRP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQMTLQLELKQIPWTEVKKASREELANLLIKHYEEQQAWNITLRIFQKMDRKDLCMKVMRERTGYTKTYQAHAKQKFSRLWSSKSVTEIHLYFEEEVKQEECDHLDRLFAPKEAGKQPRTVIIQGPQGIGKTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELRELPPTSLADLISREWPDPAAPITEIVSQPERLLFVIDSFEELQGGLNEPDSDLCGDLMEKRPVQVLLSSLLRKKMLPEASLLIAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQLFSICQIPLLCWILCTSLKQEMQKGKDLALTCQSTTSVYSSFVFNLFTPEGAEGPTPQTQHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGERESSYVFLHVCIQEFCAALFYLLKSHLDHPHPAVRCVQELLVANFEKARRAHWIFLGCFLTGLLNKKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFVKQAVNLLQEANFHIIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFKKEDEHSSTSDYSLICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFSGQSVLLFEVLFYQPDLKYLSFTLTKLSRDDIRSLCDALNYPAGNVKELALVNCHLSPIDCEVLAGLLTNNKKLTYLNVSCNQLDTGVPLLCEALCSPDTVLVYLMLAFCHLSEQCCEYISEMLLRNKSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDLASALISNQNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLASVLTCSKTLQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRKTDFDEETQALLTAEEERNPNLTITDDCDTITRVEI", "length": 994 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW", "length": 1036 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081029-8", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081029-8#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9C000-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 1", "gene_name": "NLRP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGLDQTTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS", "length": 1473 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAM1-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Lrrc34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKLQAQYCYLCSENIRKTNPFILNILQKLDEEIEKRPKEKFTVNIAGNNRLDSGQRITGEDFWLLSKTLRNQPCISGVDVRYNLIGDVGAFYAAKLLQKQPSITYLNLMFNDIGPEGGELIAKALHKNKTLKYLRMTGNKIENTGGMLFAAMLQMNSSLEKLDLGDCDLGLQCVIAFSTVLTQNQAIKGINLNRPILYGEQEESTVHIGHMLKENHVLVELHMCKHGMKNYGLQQLCNALYLNSSLRYLDVSCNKITRDGMVFLADVLKSNTTLEVLDLSFNRIETAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMKTNLVLSNIYIWGNKFDEDTCVAYSDLIKSGRLKPDNTDVEPYMVDEHIYLSEVSNGLKRHYYWAPTYGETYMPSSSAGFALVPVGEHL", "length": 415 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NX02-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 2", "gene_name": "NLRP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_706329", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706329" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVG2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVG2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-214p13.7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVG2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-25", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVG2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UVG2", "database": "AlphaFoldDB", "categories": [] }, { "id": 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This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021332332.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021332332", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332332" } ] } ], "disease": [ { "disease_id": "DOID:1928", "recommended_name": { "id": "DOID:1928", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1928", "name": "Williams-Beuren syndrome", "description": "A syndrome that is characterized by mild to moderate intellectual disability, a broad forehead, a short nose with a broad tip, full cheeks, and a wide mouth with full lips and difficulty with visual-spatial tasks and has_material_basis_in hemizygous deletion of 1.5 to 1.8 Mb on chromosome 7q11.23." }, "synonyms": [ { "id": "DOID:1928", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1928", "name": "Fanconi Schlesinger syndrome", "description": "" }, { "id": "DOID:1928", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1928", "name": "WBS", "description": "" }, { "id": "MONDO:0008678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008678", "name": "Williams syndrome", "description": "A rare genetic multisystemic neurodevelopmental disorder characterized by a distinct facial appearance, cardiac anomalies (most frequently supravalvular aortic stenosis), cognitive and developmental abnormalities, and connective tissue abnormalities (such as joint laxity)" }, { "id": "MONDO:0008678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008678", "name": "Williams syndrome", "description": "" }, { "id": "MONDO:0008678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008678", "name": "Williams-Beuren syndrome", "description": "" }, { "id": "MONDO:0008678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008678", "name": "Williams-Beuren syndrome (WBS)", "description": "" }, { "id": "MONDO:0008678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008678", "name": "deletion 7q11.23", "description": "" }, { "id": "MONDO:0008678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008678", "name": "monosomy 7q11.23", "description": "" }, { "id": "MONDO:0008678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008678", "name": "WBS", "description": "" }, { "id": "MONDO:0008678", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008678", "name": "WMS", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1928", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1928" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLI6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gtf2ird1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-010328-18", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-010328-18", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "81597", "url": "https://www.ncbi.nlm.nih.gov/gene/81597", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036647", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036647", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:81597", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:81597", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PLI6", "url": "https://www.orthodb.org/?gene=A0A8M9PLI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9QEX5", "url": "https://www.orthodb.org/?gene=A0A8M9QEX5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46304:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46304:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02946", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02946", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021332332", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332332", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLI6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QEX5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QEX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QEX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TW56", "url": "https://www.uniprot.org/uniprotkb/A0AB32TW56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TW56-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TW56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JMD0", "url": "https://www.uniprot.org/uniprotkb/A0AC58JMD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JMD0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JMD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JMD8", "url": "https://www.uniprot.org/uniprotkb/A0AC58JMD8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JMD8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JMD8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-010328-18", "url": "https://zfin.org/ZDB-GENE-010328-18", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAQIRKLGCDGMRTNSRPELKVPQVSARQEILTSLVSALDSVCSAMSKLNAEVACVTVHEDSVIAVGTEKGRIFLNSRKEIQTDFHKFCKVSCLQALNSMNSHSKVPEVDCSRTGKDSSGQQGRQRALTDTHSNIFVLRKMVEEVFSVLYSEAVGKSSLVPVPYDWILKDPSSVVVYGLPDGVTLRKPSEYDTKTLMKILEQSNRIRFIVKRTPEEPSRDAKSCPEVNHHSSTSKSASNHTSVKPSVQEVSASNSMLSSFLYGMPMSSQPHPDSKLDLKPTSLHSIGKERPGMWTPAEEKAVQAKECADNGERIGLAADLTQSPPSIHVSKRLLFSIVHEKSEKWDSFIRETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHAVRFVVRRMFDERIFTAAGKVAKEEGKQDGPASEDGFPEGLRIPSSSLELVSNTHSSRSTSSCVSPLAECEAGPSGDCLPLKKIKTEPPDGEIIQVTVPESSASTEESSEPQAERVTPDLCRPKEPVAEDLTPKSTPQGLKRAVEEDIGEMILQLRKQVESLFSCKYSEALGLPEPAKVPYSKFQMYPDDLYVTGLPEGMTFRRPNCFGAAKLRKILSASSQITFVITRPELLTEPVKNESVSKTTSESAETDSKDQSDDPGPASKRPGFSDSLEAKLSRIDLANTLREQVQDLFNRKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKISFSITRPFQGLIPKPAPRRITILKKGYTPISEEDEVNRMGEKVILREQVKELFNKKYGEALGLDRSVIVPYKLIRANPGSLEVCGLPDDIPFRNPNTYDIVRLEKVLQAQDEITFNIKTPLQPFTELCTQSCNKEGKEVSTNRRKRKRVLESSQTSMPTAGDSALSTNQIPVMQWPMYMVDYSGVNVQVPGKVKY", "length": 974, "header": "tr|A0A8M9PLI6-1|A0A8M9PLI6_DANRE Isoform 1 of General transcription factor II-I repeat domain-containing protein 1 isoform X1 OS=Danio rerio OX=7955 GN=gtf2ird1 PE=4 SV=2 CANONICAL=A0A8M9PLI6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6/entry#A0A8M9PLI6-1", "sequence": { "sequence": "MAQIRKLGCDGMRTNSRPELKVPQVSARQEILTSLVSALDSVCSAMSKLNAEVACVTVHEDSVIAVGTEKGRIFLNSRKEIQTDFHKFCKVSCLQALNSMNSHSKVPEVDCSRTGKDSSGQQGRQRALTDTHSNIFVLRKMVEEVFSVLYSEAVGKSSLVPVPYDWILKDPSSVVVYGLPDGVTLRKPSEYDTKTLMKILEQSNRIRFIVKRTPEEPSRDAKSCPEVNHHSSTSKSASNHTSVKPSVQEVSASNSMLSSFLYGMPMSSQPHPDSKLDLKPTSLHSIGKERPGMWTPAEEKAVQAKECADNGERIGLAADLTQSPPSIHVSKRLLFSIVHEKSEKWDSFIRETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHAVRFVVRRMFDERIFTAAGKVAKEEGKQDGPASEDGFPEGLRIPSSSLELVSNTHSSRSTSSCVSPLAECEAGPSGDCLPLKKIKTEPPDGEIIQVTVPESSASTEESSEPQAERVTPDLCRPKEPVAEDLTPKSTPQGLKRAVEEDIGEMILQLRKQVESLFSCKYSEALGLPEPAKVPYSKFQMYPDDLYVTGLPEGMTFRRPNCFGAAKLRKILSASSQITFVITRPELLTEPVKNESVSKTTSESAETDSKDQSDDPGPASKRPGFSDSLEAKLSRIDLANTLREQVQDLFNRKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKISFSITRPFQGLIPKPAPRRITILKKGYTPISEEDEVNRMGEKVILREQVKELFNKKYGEALGLDRSVIVPYKLIRANPGSLEVCGLPDDIPFRNPNTYDIVRLEKVLQAQDEITFNIKTPLQPFTELCTQSCNKEGKEVSTNRRKRKRVLESSQTSMPTAGDSALSTNQIPVMQWPMYMVDYSGVNVQVPGKVKY", "length": 974, "header": "tr|A0A8M9PLI6-1|A0A8M9PLI6_DANRE Isoform 1 of General transcription factor II-I repeat domain-containing protein 1 isoform X1 OS=Danio rerio OX=7955 GN=gtf2ird1 PE=4 SV=2 CANONICAL=A0A8M9PLI6-1" }, "locus": {} }, { "isoform_ac": "A0A8M9QEX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6/entry#A0A8M9QEX5-1", "sequence": { "sequence": "MAQIRKLGCDGMRTNSRPELKVPQVSARQEILTSLVSALDSVCSAMSKLNAEVACVTVHEDSVIAVGTEKGRIFLNSRKEIQTDFHKFCKVSCLQALNSMNSHSKVPEVDCSRTGKDSSGQQGRQRALTDTHSNIFVLRKMVEEVFSVLYSEAVGKSSLVPVPYDWILKDPSSVVVYGLPDGVTLRKPSEYDTKTLMKILEQSNRIRFIVKRTPEEPSRDAKSCPEVNHHSSTSKSASNHTSVKPSVQEVSASNSMLSSFLYGMPMSSQPHPDSKLDLKPTSLHSIGKERPGMWTPAEEKAVQAKECADNGERIGLAADLTQSPPSIHVSKRLLFSIVHEKSEKWDSFIRETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHAVRFVVRRMFDERIFTAAGKVAKEEGKQDGPASEDGFPEGLRIPSSSLELVSNTHSSRSTSSCVSPLAECEAGPSGDCLPLKKIKTEPPDGEIIQVTVPESSASTEESSEPQAERVTPDLCRPKEPVAEDLTPKSTPQGLKRAVEEDIGEMILQLRKQVESLFSCKYSEALGLPEPAKVPYSKFQMYPDDLYVTGLPEGMTFRRPNCFGAAKLRKILSASSQITFVITRPELLTEPVKNESVSKTTSESETDSKDQSDDPGPASKRPGFSDSLEAKLSRIDLANTLREQVQDLFNRKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKISFSITRPFQGLIPKPAPRRITILKKGYTPISEEDEVNRMGEKVILREQVKELFNKKYGEALGLDRSVIVPYKLIRANPGSLEVCGLPDDIPFRNPNTYDIVRLEKVLQAQDEITFNIKTPLQPFTELCTQSCNKEGKEVSTNRRKRKRVLESSQTSMPTAGDSALSTNQIPVMQWPMYMVDYSGVNVQVPGKVKY", "length": 973, "header": "tr|A0A8M9QEX5-1|A0A8M9PLI6_DANRE Computationally mapped isoform of General transcription factor II-I repeat domain-containing protein 1 isoform X1 OS=Danio rerio OX=7955 GN=gtf2ird1 PE=4 SV=2 CANONICAL=A0A8M9PLI6-1" }, "locus": {} }, { "isoform_ac": "A0AB32TW56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6/entry#A0AB32TW56-1", "sequence": { "sequence": "MAQIRKLGCDGMRTNSRPELKVPQVSARQEILTSLVSALDSVCSAMSKLNAEVACVTVHEDSVIAVGTEKGRIFLNSRKEIQTDFHKFCKVSCLQALNSMNSHSKVPEVDCSRTGKDSSGQQGRQRALTDTHSNIFVLRKMVEEVFSVLYSEAVGKSSLVPVPYDWILKDPSSVVVYGLPDGVTLRKPSEYDTKTLMKILEQSNRIRFIVKRTPEEPSRDAKSCPEVNHHSSTSKSASNHTSVKPSVQEVSASNSMLSSFLYGMPMSSQPHPDSKLDLKPTSLHSIGKERPGMWTPAEEKAVQAKECADNGERIGLAADLTQSPPSIHVSKRLLFSIVHEKSEKWDSFIRETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHAVRFVVRRMFDERIFTAAGKVAKEEGKQDGPASEDGFPEGLRIPSSSLELVSNTHSSRSTSSCVSPLAECEAGPSGDCLPLKKIKTEPPDGEIIQVTVPESSASTEESSEPQAERVTPDLCRPKEPVAEDLTPKSTPQGLKRAVEDIGEMILQLRKQVESLFSCKYSEALGLPEPAKVPYSKFQMYPDDLYVTGLPEGMTFRRPNCFGAAKLRKILSASSQITFVITRPELLTEPVKNESVSKTTSESETDSKDQSDDPGPASKRPGFSDSLEAKLSRIDLANTLREQVQDLFNRKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKISFSITRPFQGLIPKPAPRRITILKKGYTPISEEDEVNRMGEKVILREQVKELFNKKYGEALGLDRSVIVPYKLIRANPGSLEVCGLPDDIPFRNPNTYDIVRLEKVLQAQDEITFNIKTPLQPFTELCTQSCNKEGKEVSTNRRKRKRVLESSQTSMPTAGDSALSTNQIPVMQWPMYMVDYSGVNVQVPGKVKY", "length": 972, "header": "tr|A0AB32TW56-1|A0A8M9PLI6_DANRE Computationally mapped isoform of General transcription factor II-I repeat domain-containing protein 1 isoform X1 OS=Danio rerio OX=7955 GN=gtf2ird1 PE=4 SV=2 CANONICAL=A0A8M9PLI6-1" }, "locus": {} }, { "isoform_ac": "A0AC58JMD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6/entry#A0AC58JMD0-1", "sequence": { "sequence": "MAQIRKLGCDGMRTNSRPELKVPQVSARQEILTSLVSALDSVCSAMSKLNAEVACVTVHEDSVIAVGTEKGRIFLNSRKEIQTDFHKFCKVSCLQALNSMNSHSKVPEVDCSRTGKDSSGQQGRQRALTDTHSNIFVLRKMVEEVFSVLYSEAVGKSSLVPVPYDWILKDPSSVVVYGLPDGVTLRKPSEYDTKTLMKILEQSNRIRFIVKRTPEEPSRDAKSCPEVNHHSSTSKSASNHTSVKPSVQEVSASNSMLSSFLYGMPMSSQPHPDSKLDLKPTSLHSIGKERPGMWTPAEEKAVQAKECADNGERIGLAADLTQSPPSIHVSKRLLFSIVHEKSEKWDSFIRETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHAVRFVVRRMFDERIFTAAGKVAKEEGKQDGPASEDGFPEGLRIPSSSLELVSNTHSSRSTSSCVSPLAECEAGPSGDCLPLKKIKTEPPDGEIIQVTVPESSASTEESSEPQAERVTPDLCRPKEPVAEDLTPKSTPQGLKRAVEDIGEMILQLRKQVESLFSCKYSEALGLPEPAKVPYSKFQMYPDDLYVTGLPEGMTFRRPNCFGAAKLRKILSASSQITFVITRPELLTEPVKNESVSKTTSESAETDSKDQSDDPGPASKRPGFSDSLEAKLSRIDLANTLREQVQDLFNRKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKISFSITRPFQGLIPKPAPRRITILKKGYTPISEEDEVNRMGEKVILREQVKELFNKKYGEALGLDRSVIVPYKLIRANPGSLEVCGLPDDIPFRNPNTYDIVRLEKVLQAQDEITFNIKTPLQPFTELCTQSCNKEGKEVSTNRRKRKRVLESSQTSMPTAGDSALSTNQIPVMQWPMYMVDYSGVNVQVPGKVKY", "length": 973, "header": "tr|A0AC58JMD0-1|A0AC58JMD0_DANRE Computationally mapped isoform of General transcription factor II-I repeat domain-containing protein 1 isoform X2 OS=Danio rerio OX=7955 GN=gtf2ird1 PE=4 SV=1 CANONICAL=A0A8M9PLI6-1" }, "locus": {} }, { "isoform_ac": "A0AC58JMD8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6/entry#A0AC58JMD8-1", "sequence": { "sequence": "MAQIRKLGCDGMRTNSRPELKVPQVSARQEILTSLVSALDSVCSAMSKLNAEVACVTVHEDSVIAVGTEKGRIFLNSRKEIQTDFHKFCKVSCLQALNSMNSHSKVPEVDCSRTGKDSSGQQGRQRALTDTHSNIFVLRKMVEEVFSVLYSEAVGKSSLVPVPYDWILKDPSSVVVYGLPDGVTLRKPSEYDTKTLMKILEQSNRIRFIVKRTPEEPSRDAKSCPEVNHHSSTSKSASNHTSVKPSVQEVSASNSMLSSFLYGMPMSSQPHPDSKLDLKPTSLHSIGKERPGMWTPAEEKAVQAKECADNGERIGLAADLTQSPPSIHVSKRLLFSIVHEKSEKWDSFIRETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIIGIPDKIPFKRPCTYGVPKLKRILEERHAVRFVVRRMFDERIFTAAGKVAKEEGKQDGPASEDGFPEGLRIPSSSLELVSNTHSSRSTSSCVSPLAECEAGPSGDCLPLKKIKTEPPDGEIIQVTVPESSASTEESSEPQAERVTPDLCRPKEPVAGNIKLAYIRTYFLIHLFFSLWYCTDNPKHMTNQSL", "length": 587, "header": "tr|A0AC58JMD8-1|A0AC58JMD8_DANRE Computationally mapped isoform of General transcription factor II-I repeat domain-containing protein 1 isoform X5 OS=Danio rerio OX=7955 GN=gtf2ird1 PE=4 SV=1 CANONICAL=A0A8M9PLI6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:81597", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:81597", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KA15-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 1", "gene_name": "Gtf2ird1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALLGKHCDIPTNGCGSERWNSTFARKDELINSLVSALDSMCSALSKLNTEVACVAVHNESVFVMGTEKGRVFLNTRKELQSDFLRFCRGPLWNDPEAGHPKKVQRCEGGGRSIPRSSLEQCSDVYLLQKMVEEVFDVLYSEAMGRATVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLRRPPDDGGQDTKALVEMNGISLLPKGSRDCGLHGQASKVSPQDLTPTATPSSMANFLYSTSMPNHTIRELKQEVPTCPLTPSDLGLGWPVPEPHVPSTQDFSDCCGQAPAGPAGPLIQNVHASKRILFSIVHDKSEKWDPFIKEMEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDPMKLEPASPPEDTATEVCRDSMLDLAGTAWSDMSSVSEDCGPGTSGEIGMLRPIKIEPEELDIIQVTVSDPSPTSEEMTDSLPGHLPSEDSGYGMEMPADKGPSEEPWQEERPAEESPGDVIRPLRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTDGVKEPVMDTQERDSWDPLVDETPKRQGLQENYNTRLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKARDHVRMVIINQLQPFTEVCNDPKVPAKDNIPKRKRKRVSEGNSVSSSSSSSSSSSSNPESVASTNQISLVQWPVYMVDYSGLNVQLPGPLDY", "length": 943 }, "evidence": [ { "id": "RGD:620856", "url": "https://alliancegenome.org/gene/RGD:620856#orthology", "database": "AGR" }, { "id": "HGNC:4661", "url": "https://alliancegenome.org/gene/HGNC:4661#orthology", "database": "AGR" }, { "id": "MGI:1861942", "url": "https://alliancegenome.org/gene/MGI:1861942#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-010328-18", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-010328-18#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JI57-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 1", "gene_name": "Gtf2ird1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLGKHCDIPTNGCGSERWNSTFARKDELINSLVSALDSMCSALSKLNTEVACVAVHNESVFVMGTEKGRVFLNTRKELQSDFLRFCRGPLWNDPEAGHPKKVQRCEGGGRSLPRSSLEQCSDVYLLQKMVEEVFDVLYSEAMGRATVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLRRPPDDGGQDTKALVEMNGISLLPKGSRDCGLHGQASKVAPQDLTPTATPSSMANFLYSTSMPNHTIRELKQEVPTCPLTPSDLGMGWPVPEPHVPSTQDFSDCCGQTPAGPAGPLIQNVHASKRILFSIVHDKSEKWDPFIKEMEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDPMKLEPASPPEDTSTEVCRDSMLDLAGTAWSDMSSVSEDCGPGTSGEIAMLRPIKIEPEELDIIQVTVSDPSPTSEEMTDSLPGHLPSEDSGYGMEMPADKGPSEEPWSEERPAEESPGDVIRPLRKQVEMLFNTKYAKAIGTSEPVKVPYSKFLMHPEELFVLGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTDGVKEPVLDTQERDSWDRLVDETPKRQGLQENYNTRLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILSVADKIKFTVTRPFQGLIPKPETKILTTGHEAGKTTRPRRLQQDTWQPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEVCNDPKVPEEDDSNKLGKKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVKGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFGDVCNNAKVPAKDNIPKRKRKRVSEGNSVSSSSSSSSSSSNPESVASTNQISLVVKSRGSELHPNSVWPLPLPRAGPSTAPGTGRHWALRGTQPTTEGQAHPLVLPTR", "length": 1104 }, "evidence": [ { "id": "RGD:620856", "url": "https://alliancegenome.org/gene/RGD:620856#orthology", "database": "AGR" }, { "id": "HGNC:4661", "url": "https://alliancegenome.org/gene/HGNC:4661#orthology", "database": "AGR" }, { "id": "MGI:1861942", "url": "https://alliancegenome.org/gene/MGI:1861942#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-010328-18", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-010328-18#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHL9-1", "protein_name": "General transcription factor II-I repeat domain-containing protein 1", "gene_name": "GTF2IRD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLGKRCDVPTNGCGPDRWNSAFTRKDEIITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCRGPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRPLEDGGRDSKALVELNGVSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSMASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGPGGPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPASPPEDTSAEVSRATVLDLAGNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTSEEMTDSMPGHLPSEDSGYGMEMLTDKGLSEDARPEERPVEDSHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNCFGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIMDSQGTASSLGFSPPALPPERDSGDPLVDESLKRQGFQENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPNTYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAKVPAKDSSIPKRKRKRVSEGNSVSSSSSSSSSSSSNPDSVASANQISLVQWPMYMVDYAGLNVQLPGPLNY", "length": 959 }, "evidence": [ { "id": "RGD:620856", "url": "https://alliancegenome.org/gene/RGD:620856#orthology", "database": "AGR" }, { "id": "HGNC:4661", "url": "https://alliancegenome.org/gene/HGNC:4661#orthology", "database": "AGR" }, { "id": "MGI:1861942", "url": "https://alliancegenome.org/gene/MGI:1861942#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-010328-18", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-010328-18#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLI6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLI6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLI6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLI6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 239, "end_pos": 241, "annotation": "n_glycosylation_sequon" }, { "start_pos": 663, "end_pos": 665, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 239, "end_pos": 241 }, { "start_pos": 663, "end_pos": 665 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0JME6-1", "uniprot_ac": "A0JME6", "uniprot_id": "ISOC2_DANRE", "mass": { "chemical_mass": 21491.0, "monoisotopic_mass": 21491.0 }, "refseq": { "ac": "NP_001073422", "name": "isochorismatase domain-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073422" }, "gene_names": [ { "name": "isoc2", "type": "recommended", "evidence": [ { "id": "A0JME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JME6" } ] }, { "name": "im:7143522", "type": "synonym", "evidence": [ { "id": "NP_001073422", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073422" }, { "id": "A0JME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JME6" } ] }, { "name": "isoc2", "type": "synonym", "evidence": [ { "id": "NP_001073422", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073422" } ] }, { "name": "zgc:109735", "type": "synonym", "evidence": [ { "id": "NP_001073422", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073422" }, { "id": "A0JME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JME6" } ] } ], "protein_names": [ { "name": "Isochorismatase domain-containing protein 2", "type": "recommended", "evidence": [ { "id": "A0JME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0JME6/entry#names_and_taxonomy" } ] }, { "name": "isochorismatase domain-containing protein 2, mitochondrial", "type": "synonym", "evidence": [ { "id": "NP_001073422", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073422" } ] }, { "name": "isochorismatase domain-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001073422", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073422" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC125848.1, EH583860.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC125848.1 and CR848818.10. On May 23, 2007 this sequence version replaced NP_001073422.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001073422", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073422" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0JME6", "url": "https://www.uniprot.org/uniprotkb/A0JME6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "isoc2", "url": "https://www.uniprot.org/uniprotkb/A0JME6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070518-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070518-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0JME6", "url": "https://alphafold.ebi.ac.uk/entry/A0JME6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000013371", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000013371", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01012", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01012", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "492617", "url": "https://www.ncbi.nlm.nih.gov/gene/492617", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:492617", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492617", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HVCVFQT", "url": "https://omabrowser.org/oma/group/HVCVFQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0JME6", "url": "https://www.orthodb.org/?gene=A0JME6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14119:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14119:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A0JME6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A0JME6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001073422", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073422", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32T6B3", "url": "https://www.uniprot.org/uniprotkb/A0AB32T6B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T6B3-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T6B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0JME6", "url": "https://www.uniprot.org/uniprotkb/A0JME6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0JME6-1", "url": "https://www.uniprot.org/uniprotkb/A0JME6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070518-1", "url": "https://zfin.org/ZDB-GENE-070518-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAGIGRLSTKGSVLLLCDMQEKFRPTIFQFTNVVSNAARLLQACRILNIPQILTEQYPKGLGPTVPELGAEGLKPHTKTSFSMMTESVQSSLKSMGDPQQVILCGIEAQACIACTAYDLLERGMEVHIVADAVSSRSQTDRLFALSRLRQSGVFLNTTEGVLLQLVQDAKHPNFKEIQKLLAHPSPDTGLLAFFSSL", "length": 197, "header": "sp|A0JME6-1|ISOC2_DANRE Isoform 1 of Isochorismatase domain-containing protein 2 OS=Danio rerio OX=7955 GN=isoc2 PE=2 SV=1 CANONICAL=A0JME6-1" }, "isoforms": [ { "isoform_ac": "A0AB32T6B3-1", "url": "https://www.uniprot.org/uniprotkb/A0JME6/entry#A0AB32T6B3-1", "sequence": { "sequence": "MAGIGRLSTKGSVLLLCDMQEKFRPTIFQFTNVVSNAARLLQACRILNIPQILTEQYPKGLGPTVPELGAEGLKPHTKTSFSMMTESVQSSLKSMGDPQQVILCGIEAQACIACTAYDLLERGMEVHIVADAVSSRRSRNSWLTPPLIQACWPSSALYRASQTQTTPCRHNYRNY", "length": 175, "header": "tr|A0AB32T6B3-1|ISOC2_DANRE Computationally mapped isoform of Isochorismatase domain-containing protein 2 OS=Danio rerio OX=7955 GN=isoc2 PE=2 SV=1 CANONICAL=A0JME6-1" }, "locus": {} }, { "isoform_ac": "A0JME6-1", "url": "https://www.uniprot.org/uniprotkb/A0JME6/entry#A0JME6-1", "sequence": { "sequence": "MAGIGRLSTKGSVLLLCDMQEKFRPTIFQFTNVVSNAARLLQACRILNIPQILTEQYPKGLGPTVPELGAEGLKPHTKTSFSMMTESVQSSLKSMGDPQQVILCGIEAQACIACTAYDLLERGMEVHIVADAVSSRSQTDRLFALSRLRQSGVFLNTTEGVLLQLVQDAKHPNFKEIQKLLAHPSPDTGLLAFFSSL", "length": 197, "header": "sp|A0JME6-1|ISOC2_DANRE Isoform 1 of Isochorismatase domain-containing protein 2 OS=Danio rerio OX=7955 GN=isoc2 PE=2 SV=1 CANONICAL=A0JME6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 64, "start_aa": "Thr", "end_pos": 64, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr64", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:492617", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492617", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UAV9-1", "protein_name": "Isochorismatase domain containing 2", "gene_name": "ISOC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAVRPGLGRVVPGSSILFLCDMQEKFRHTLYFPQIVSVAARMLKVARLLDVPVVLTEQYPQGLGPTVPELGAKGLQPRPKTCFSMVPVVQHELDARPQLRSVLLCGLETQACILHTALDLLDQGLQVHVVVDACTSRSQVDRLVALSRMRQSGAFLSTSEGLILQLVGDAAHPQFKEIQKIIKEPTPDSGLLGLFHGQNPLFR", "length": 204 }, "evidence": [ { "id": "A0JME6", "url": "https://omabrowser.org/oma/group/A0JME6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6GL72-1", "protein_name": "Isochorismatase domain containing 2A", "gene_name": "Isoc2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARASLGRIRPESSILFLCDMQEKFRPSIAYFPQIVSVAARMLKVARLLDVPILLTEQYPQGLGPTVPELGAQGIKPVSKTCFSMVPSLQKELDRRSQLQSVLLCGIETQACILNTVLDLLDRGLQVHVVVDACSSRSQIDRLVALGRMRQSGAFLSTSESLILQLVRDAAHPQFKEIQKIIKEPAPDSGLLGLFQESWIGRTIHVYLVISS", "length": 214 }, "evidence": [ { "id": "A0JME6", "url": "https://omabrowser.org/oma/group/A0JME6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P85094-1", "protein_name": "Isochorismatase domain-containing protein 2A", "gene_name": "Isoc2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAARASLGRILPESSILFLCDLQEKFRPSIAYFPQIVSVAARMLKVARLLDVPILLTEQYPEGLGPTVPELGAQGIRPVSKTCFSMVPALQKELDGRSQLQSVLLCGIETQACILNTALDLLHRGLQVHVVVDACSSRSQVDRLVALARMRQSGAFLATSESLILQLVRDASHPQFKEIQKIIKEPVPDSGLLSLFQGQSPLTSC", "length": 206 }, "evidence": [ { "id": "HGNC:26278", "url": "https://alliancegenome.org/gene/HGNC:26278#orthology", "database": "AGR" }, { "id": "MGI:3609243", "url": "https://alliancegenome.org/gene/MGI:3609243#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070518-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070518-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0035044", "url": "https://alliancegenome.org/gene/FB:FBgn0035044#orthology", "database": "AGR" }, { "id": "FB:FBgn0039850", "url": "https://alliancegenome.org/gene/FB:FBgn0039850#orthology", "database": "AGR" }, { "id": "A0JME6", "url": "https://omabrowser.org/oma/group/A0JME6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q08C33-1", "protein_name": "Isochorismatase domain-containing protein 1", "gene_name": "isoc1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADTHSNNNHVPVLFSFSVFSRASSVPVGSGYEVLIQKFLSIYGSQIDVHRKLVLQYFSEEWGQYIDLPKGFTVSEKCRLRLVPLQMDITTLGNLSPATSVFFCCDMQERFRPAIKYFGDIISVGQRLLQGARILGIPVVVSEQYPKGLGSTVQEMDLTGAKLVFPKTKFSMVIPELEAALAEIPGVRSVVLFGVETHVCIQQTALDLIGRGFEVHIVADATSSRSMMDRMFALERLARTGIIITTSESVLLQLVADKEHPKFKEIQNIIKVSAPESGLLSKV", "length": 283 }, "evidence": [ { "id": "FB:FBgn0035044", "url": "https://alliancegenome.org/gene/FB:FBgn0035044#orthology", "database": "AGR" }, { "id": "FB:FBgn0039850", "url": "https://alliancegenome.org/gene/FB:FBgn0039850#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q54NZ8-1", "protein_name": "Isochorismatase family protein 1B", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MIRSLGKIVPETSALFICDIQSKFANHIFKFNGVVNQSKYMMRVCNELKVPIIFTEQYPKGLGHTFEDLLKERNENNQTKIFEKTLYSMCTNEVLNHLKQNHKDLKSILITGIETHVCVLQSTLDFLENGYDVHILSDAVSSNNNNDRLIALERMRQSGAFITTTESIIFQLTRDATHKSFKSIVPITKQRRDDLVADPSLSLSKM", "length": 206 }, "evidence": [ { "id": "A0JME6", "url": "https://omabrowser.org/oma/group/A0JME6/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5U3Z3-1", "protein_name": "Isochorismatase domain-containing protein 2", "gene_name": "Isoc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAARASLGRIFPESSILFLCDMQEKLRDRVLYFPQIVSMAARMLKVARILDVPVLLTEHYPQGLGPTVPELGAQGVRTMSKTSFSMVPPLQQELDKLPQLKSVLLCGIETQVCILNTALDLLDRGLQVHVAVDACSSQSEMNRLVALARMQHSGVFLSTSEALTLQLIKDAAHPQFKEIQKILKEPVPEIGLLGFFQGMNNPLLPNSRP", "length": 210 }, "evidence": [ { "id": "HGNC:26278", "url": "https://alliancegenome.org/gene/HGNC:26278#orthology", "database": "AGR" }, { "id": "RGD:1309062", "url": "https://alliancegenome.org/gene/RGD:1309062#orthology", "database": "AGR" }, { "id": "MGI:1914691", "url": "https://alliancegenome.org/gene/MGI:1914691#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070518-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070518-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0035044", "url": "https://alliancegenome.org/gene/FB:FBgn0035044#orthology", "database": "AGR" }, { "id": "FB:FBgn0039850", "url": "https://alliancegenome.org/gene/FB:FBgn0039850#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6I7R3-1", "protein_name": "Isochorismatase domain-containing protein 1", "gene_name": "Isoc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAAEPSVAALAGGGVGAGAPSGGVPVLFCFSVFARPASVPHGAGYDVLIQKFLSLYGDQVDMHRKFVVQLFAEEWGQYVDLPKGFAVSERCKLRLVPLQIQLTTLGNLTPPSTVFFCCDMQERFRPAIKYFGDIISVGQRLLQGARILGIPVIITEQYPKGLGSTVQEIDLTGVKLVLPKTKFSMVLPEVEAALAEIPGVRSVVLFGVETHVCIQQTALELVGRGIEVHIVADATSSRSMMDRMFALERLARTGIIVTTSEAVPLQLVADKDHPKFKEIQNLIKASAPESGLLSKV", "length": 297 }, "evidence": [ { "id": "FB:FBgn0035044", "url": "https://alliancegenome.org/gene/FB:FBgn0035044#orthology", "database": "AGR" }, { "id": "FB:FBgn0039850", "url": "https://alliancegenome.org/gene/FB:FBgn0039850#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91V64-1", "protein_name": "Isochorismatase domain-containing protein 1", "gene_name": "Isoc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAEPSVAALAGGGVGAGAPSGGVPVLFCFSVFARPASVPHGAGYDVLIQKFLSLYGDQLDMHRKFVVQLFAEEWGQYVDLPKGFAVSERCKLRLVPLQIQLTTLGNLTPPSTVFFCCDMQERFRPAIKYFGDIISVGQRLLQGARILGIPVIITEQYPKGLGSTVQEIDLTGVKLVLPKTKFSMVLPEVEAALAEIPGVRSVVLFGVETHVCIQQTALELVGRGIEVHIVADATSSRSMMDRMFALERLARTGIIVTTSEAVLLQLVADKDHPKFKEIQNLIKASAPESGLLSKV", "length": 297 }, "evidence": [ { "id": "FB:FBgn0035044", "url": "https://alliancegenome.org/gene/FB:FBgn0035044#orthology", "database": "AGR" }, { "id": "FB:FBgn0039850", "url": "https://alliancegenome.org/gene/FB:FBgn0039850#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96AB3-1", "protein_name": "Isochorismatase domain-containing protein 2", "gene_name": "ISOC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAARPSLGRVLPGSSVLFLCDMQEKFRHNIAYFPQIVSVAARMLKVARLLEVPVMLTEQYPQGLGPTVPELGTEGLRPLAKTCFSMVPALQQELDSRPQLRSVLLCGIEAQACILNTTLDLLDRGLQVHVVVDACSSRSQVDRLVALARMRQSGAFLSTSEGLILQLVGDAVHPQFKEIQKLIKEPAPDSGLLGLFQGQNSLLH", "length": 205 }, "evidence": [ { "id": "HGNC:26278", "url": "https://alliancegenome.org/gene/HGNC:26278#orthology", "database": "AGR" }, { "id": "RGD:1309062", "url": "https://alliancegenome.org/gene/RGD:1309062#orthology", "database": "AGR" }, { "id": "MGI:3609243", "url": "https://alliancegenome.org/gene/MGI:3609243#orthology", "database": "AGR" }, { "id": "MGI:1914691", "url": "https://alliancegenome.org/gene/MGI:1914691#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070518-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070518-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0035044", "url": "https://alliancegenome.org/gene/FB:FBgn0035044#orthology", "database": "AGR" }, { "id": "FB:FBgn0039850", "url": "https://alliancegenome.org/gene/FB:FBgn0039850#orthology", "database": "AGR" }, { "id": "A0JME6", "url": "https://omabrowser.org/oma/group/A0JME6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96CN7-1", "protein_name": "Isochorismatase domain-containing protein 1", "gene_name": "ISOC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAEPAVLALPNSGAGGAGAPSGTVPVLFCFSVFARPSSVPHGAGYELLIQKFLSLYGDQIDMHRKFVVQLFAEEWGQYVDLPKGFAVSERCKVRLVPLQIQLTTLGNLTPSSTVFFCCDMQERFRPAIKYFGDIISVGQRLLQGARILGIPVIVTEQYPKGLGSTVQEIDLTGVKLVLPKTKFSMVLPEVEAALAEIPGVRSVVLFGVETHVCIQQTALELVGRGVEVHIVADATSSRSMMDRMFALERLARTGIIVTTSEAVLLQLVADKDHPKFKEIQNLIKASAPESGLLSKV", "length": 298 }, "evidence": [ { "id": "FB:FBgn0035044", "url": "https://alliancegenome.org/gene/FB:FBgn0035044#orthology", "database": "AGR" }, { "id": "FB:FBgn0039850", "url": "https://alliancegenome.org/gene/FB:FBgn0039850#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DCC7-1", "protein_name": "Isochorismatase domain-containing protein 2B", "gene_name": "Isoc2b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGAAKASLGRIFPESSILFLCDMQEKLRDRILYFPQIVSKAARMLKVAQMLEIPVLLTEHYPQGLGPTVPELGAQGLRTMSKTSFSMVPPLQQELDKLPQLQSVLLCGIETQGCILHTALDLLDRGLQVHVAVDACSSQSEMNRLVALARMQQSGVFLSTSEVLILQLVKDAAHPQFKEIQKILKEPVTDIGLLGFFQGKKNSLLPNSRT", "length": 210 }, "evidence": [ { "id": "HGNC:26278", "url": "https://alliancegenome.org/gene/HGNC:26278#orthology", "database": "AGR" }, { "id": "RGD:1309062", "url": "https://alliancegenome.org/gene/RGD:1309062#orthology", "database": "AGR" }, { "id": "MGI:1914691", "url": "https://alliancegenome.org/gene/MGI:1914691#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070518-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070518-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0035044", "url": "https://alliancegenome.org/gene/FB:FBgn0035044#orthology", "database": "AGR" }, { "id": "FB:FBgn0039850", "url": "https://alliancegenome.org/gene/FB:FBgn0039850#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V9X3-1", "protein_name": "Isochorismatase-like domain-containing protein", "gene_name": "Dmel\\CG11333", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKVRGPALYRLVPSKTLFMLCDVQEKFKPAIPLLSSLIENTTKLLAAGKVFQVPLLVTEQYPERLGKTVCELDIKHACANISKTMFSMLVEPVRKSMTDIFGGKPKTVVLFGLETHVCVEQTAFDLVNDEIDVWLVADCCASRHNQDRDLALERLRHIGCNIATSESVIFNLLGDKNNKSFKEITPLVKKISADMQLCRVSKN", "length": 204 }, "evidence": [ { "id": "HGNC:26278", "url": "https://alliancegenome.org/gene/HGNC:26278#orthology", "database": "AGR" }, { "id": "RGD:1309062", "url": "https://alliancegenome.org/gene/RGD:1309062#orthology", "database": "AGR" }, { "id": "MGI:3609243", "url": "https://alliancegenome.org/gene/MGI:3609243#orthology", "database": "AGR" }, { "id": "MGI:1914691", "url": "https://alliancegenome.org/gene/MGI:1914691#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070518-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070518-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0039850", "url": "https://alliancegenome.org/gene/FB:FBgn0039850#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W127-1", "protein_name": "Isochorismatase-like domain-containing protein", "gene_name": "Dmel\\CG3663", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALRRCHLNPKKTLFLLCDIQEKFRPAMPLFDNMIKNVDKLTRAGKALDVPLIVTEHYPEKLGKTVAQLDVSHAKLVSGKTLFSMFTPEVKAVIKDIFNDKPEDVVLYGLESHICVEQTAIDLLEQNINVYIVADCCSSRLNQDRDLALDRLRQAGCVITTSESVIFDLVRDKNNPKFDVVRKLVNQPSVDMELTRNGSGVPAGSAKL", "length": 208 }, "evidence": [ { "id": "HGNC:26278", "url": "https://alliancegenome.org/gene/HGNC:26278#orthology", "database": "AGR" }, { "id": "RGD:1309062", "url": "https://alliancegenome.org/gene/RGD:1309062#orthology", "database": "AGR" }, { "id": "MGI:3609243", "url": "https://alliancegenome.org/gene/MGI:3609243#orthology", "database": "AGR" }, { "id": "MGI:1914691", "url": "https://alliancegenome.org/gene/MGI:1914691#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070518-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070518-1#orthology", "database": "AGR" }, { "id": "FB:FBgn0035044", "url": "https://alliancegenome.org/gene/FB:FBgn0035044#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0JME6", "url": "https://www.uniprot.org/uniprotkb/A0JME6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 64 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 156, "end_pos": 158 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A1L2F6-1", "uniprot_ac": "A1L2F6", "uniprot_id": "TM205_DANRE", "mass": { "chemical_mass": 21301.0, "monoisotopic_mass": 21301.0 }, "refseq": { "ac": "NP_001074155", "name": "transmembrane protein 205", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074155" }, "gene_names": [ { "name": "tmem205", "type": "recommended", "evidence": [ { "id": "A1L2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1L2F6" } ] }, { "name": "tmem205", "type": "synonym", "evidence": [ { "id": "NP_001074155", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074155" } ] }, { "name": "zgc:158860", "type": "synonym", "evidence": [ { "id": "NP_001074155", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074155" }, { "id": "A1L2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1L2F6" } ] } ], "protein_names": [ { "name": "Transmembrane protein 205", "type": "recommended", "evidence": [ { "id": "A1L2F6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1L2F6/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 205", "type": "synonym", "evidence": [ { "id": "NP_001074155", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074155" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC129498.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC129498.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001074155", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074155" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1L2F6", "url": "https://www.uniprot.org/uniprotkb/A1L2F6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmem205", "url": "https://www.uniprot.org/uniprotkb/A1L2F6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070112-1692", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-1692", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A1L2F6", "url": "https://alphafold.ebi.ac.uk/entry/A1L2F6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000100677", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000100677", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "791204", "url": "https://www.ncbi.nlm.nih.gov/gene/791204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025423", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025423", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:791204", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:791204", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQMRAVE", "url": "https://omabrowser.org/oma/group/FQMRAVE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A1L2F6", "url": "https://www.orthodb.org/?gene=A1L2F6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46916", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46916", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46916:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46916:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A1L2F6", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A1L2F6", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001074155", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001074155", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TGA9", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TGA9-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TGA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A1L2F6", "url": "https://www.uniprot.org/uniprotkb/A1L2F6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A1L2F6-1", "url": "https://www.uniprot.org/uniprotkb/A1L2F6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070112-1692", "url": "https://zfin.org/ZDB-GENE-070112-1692", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MATEGDPTDFVKVLHLLVISFTWGMQVWVSFIAGFVLISQVSMHTFGLVQSKLFPVYFYCLLGGNAVSLAVYAVYHPRELLDWHEGIQMSLFFVAVIMAGLNAQWFGPSATENMLVMQEIEKEHGLGNQVGMSSNREGYTKLREQDPKYKEHRSTFYRYHGLSNLCNLIGFFCITVNLIYLALNLGTI", "length": 188, "header": "sp|A1L2F6-1|TM205_DANRE Isoform 1 of Transmembrane protein 205 OS=Danio rerio OX=7955 GN=tmem205 PE=2 SV=1 CANONICAL=A1L2F6-1" }, "isoforms": [ { "isoform_ac": "A0AB32TGA9-1", "url": "https://www.uniprot.org/uniprotkb/A1L2F6/entry#A0AB32TGA9-1", "sequence": { "sequence": "MAFQPKIIMATEGDPTDFVKVLHLLVISFTWGMQVWVSFIAGFVLISQVSMHTFGLVQSKLFPVYFYCLLGGNAVSLAVYAVYHPRELLDWHEGIQMSLFFVAVIMAGLNAQWFGPSATENMLVMQEIEKEHGLGNQVGMSSNREGYTKLREQDPKYKEHRSTFYRYHGLSNLCNLIGFFCITVNLIYLALNLGTI", "length": 196, "header": "tr|A0AB32TGA9-1|TM205_DANRE Computationally mapped isoform of Transmembrane protein 205 OS=Danio rerio OX=7955 GN=tmem205 PE=2 SV=1 CANONICAL=A1L2F6-1" }, "locus": {} }, { "isoform_ac": "A1L2F6-1", "url": "https://www.uniprot.org/uniprotkb/A1L2F6/entry#A1L2F6-1", "sequence": { "sequence": "MATEGDPTDFVKVLHLLVISFTWGMQVWVSFIAGFVLISQVSMHTFGLVQSKLFPVYFYCLLGGNAVSLAVYAVYHPRELLDWHEGIQMSLFFVAVIMAGLNAQWFGPSATENMLVMQEIEKEHGLGNQVGMSSNREGYTKLREQDPKYKEHRSTFYRYHGLSNLCNLIGFFCITVNLIYLALNLGTI", "length": 188, "header": "sp|A1L2F6-1|TM205_DANRE Isoform 1 of Transmembrane protein 205 OS=Danio rerio OX=7955 GN=tmem205 PE=2 SV=1 CANONICAL=A1L2F6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:791204", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:791204", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0M4C2-1", "protein_name": "Transmembrane protein 205", "gene_name": "TMEM205", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEEGGNPGSLTKVVHLLVLSGAWGMQVWVTFVSGFLLFRGLPRHTFGLVQSKLFPFYFHISMGSAFINLCVLASQHAWAQLTFWEASQLCLLLVSLTLATINARWLEPRTTATMWALQTMEKERGLGGEVPGSHQGSDPYRQLRGQDPKYSALRQNFFRYHGLSSICNLGCLLSNGLHLAGLALGLRGL", "length": 189 }, "evidence": [ { "id": "A1L2F6", "url": "https://omabrowser.org/oma/group/A1L2F6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZJZ0-1", "protein_name": "Transmembrane protein 205", "gene_name": "Tmem205", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEGEDPGSLIKVIHLLVLSGVWGMQMWVTFASGFLLFRSLPRHTFGLVQSKLFPVYFHVSLGCAFINLCILAPQRAWINLTLWEISQLTLLLLSLTLATINARWLEARTTATMWALQSIEKERGLGTEVPGSLQGPDPYRQLREKDPKYSALRQKFFYYHGLSSLCNLGCLLSNGLCLVGLALGLRSL", "length": 189 }, "evidence": [ { "id": "RGD:1563250", "url": "https://alliancegenome.org/gene/RGD:1563250#orthology", "database": "AGR" }, { "id": "MGI:3045495", "url": "https://alliancegenome.org/gene/MGI:3045495#orthology", "database": "AGR" }, { "id": "HGNC:29631", "url": "https://alliancegenome.org/gene/HGNC:29631#orthology", "database": "AGR" }, { "id": "FB:FBgn0052512", "url": "https://alliancegenome.org/gene/FB:FBgn0052512#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-1692", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-1692#orthology", "database": "AGR" }, { "id": "SGD:S000006302", "url": "https://alliancegenome.org/gene/SGD:S000006302#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q06089-1", "protein_name": "Uncharacterized mitochondrial outer membrane protein YPR098C", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MCLVKTTAHLLFYSFVFGGTTFYSYVASPIAFKVLEKDQFSALQNKIFPYFFQMQAASPVILALTAPIALTTGPLSSLVVASVSGLTNLFWLLPWTHKVKEQRKNIAKKYTGSELEAKDAILRKEFGKSHGLSLLFNLSNVCGMLAYGVCLSGGLLRKIPK", "length": 161 }, "evidence": [ { "id": "RGD:1563250", "url": "https://alliancegenome.org/gene/RGD:1563250#orthology", "database": "AGR" }, { "id": "MGI:3045495", "url": "https://alliancegenome.org/gene/MGI:3045495#orthology", "database": "AGR" }, { "id": "HGNC:29631", "url": "https://alliancegenome.org/gene/HGNC:29631#orthology", "database": "AGR" }, { "id": "FB:FBgn0052512", "url": "https://alliancegenome.org/gene/FB:FBgn0052512#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-1692", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-1692#orthology", "database": "AGR" }, { "id": "SGD:S000006302", "url": "https://alliancegenome.org/gene/SGD:S000006302#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q32L10-1", "protein_name": "Transmembrane protein 205", "gene_name": "TMEM205", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEEGGNPGSLTKVVHLLVLSGAWGMQMWVTFISGFVLFRGLPRHTFGLVQSKLFPFYFHISMGCAFVNLCILASQCSWAQLTFWEASQLFLLLLSLTLATINARWLESRTTAAMWALQTVEKERGLGGEVPGSHQGSDPYHQLRGQDPKYSALRQQFFRYHGLSSLCNLGCLLSNGLHLAGLALALHNL", "length": 189 }, "evidence": [ { "id": "A1L2F6", "url": "https://omabrowser.org/oma/group/A1L2F6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6UW68-1", "protein_name": "Transmembrane protein 205", "gene_name": "TMEM205", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEGGNLGGLIKMVHLLVLSGAWGMQMWVTFVSGFLLFRSLPRHTFGLVQSKLFPFYFHISMGCAFINLCILASQHAWAQLTFWEASQLYLLFLSLTLATVNARWLEPRTTAAMWALQTVEKERGLGGEVPGSHQGPDPYRQLREKDPKYSALRQNFFRYHGLSSLCNLGCVLSNGLCLAGLALEIRSL", "length": 189 }, "evidence": [ { "id": "RGD:1563250", "url": "https://alliancegenome.org/gene/RGD:1563250#orthology", "database": "AGR" }, { "id": "MGI:3045495", "url": "https://alliancegenome.org/gene/MGI:3045495#orthology", "database": "AGR" }, { "id": "HGNC:29631", "url": "https://alliancegenome.org/gene/HGNC:29631#orthology", "database": "AGR" }, { "id": "FB:FBgn0052512", "url": "https://alliancegenome.org/gene/FB:FBgn0052512#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-1692", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-1692#orthology", "database": "AGR" }, { "id": "SGD:S000006302", "url": "https://alliancegenome.org/gene/SGD:S000006302#orthology", "database": "AGR" }, { "id": "A1L2F6", "url": "https://omabrowser.org/oma/group/A1L2F6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91XE8-1", "protein_name": "Transmembrane protein 205", "gene_name": "Tmem205", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKGEDPGSLIKVIHLLVLSGAWGMQVWVTFISGFLLFRSLPRHTFGLVQSKVFPVYFHVSLGCAFINLCILAPQRAWIHLTLWEVSQLSLLLLSLTLATINARWLEARTTAVMRALQSIEKERGLGTEVPGNFQGPDPYRQLRDKDPKYSALRRKFYHYHGLSSLCNLGCLLSNGLCLVGLALGLRSL", "length": 189 }, "evidence": [ { "id": "RGD:1563250", "url": "https://alliancegenome.org/gene/RGD:1563250#orthology", "database": "AGR" }, { "id": "MGI:3045495", "url": "https://alliancegenome.org/gene/MGI:3045495#orthology", "database": "AGR" }, { "id": "HGNC:29631", "url": "https://alliancegenome.org/gene/HGNC:29631#orthology", "database": "AGR" }, { "id": "FB:FBgn0052512", "url": "https://alliancegenome.org/gene/FB:FBgn0052512#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-1692", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-1692#orthology", "database": "AGR" }, { "id": "SGD:S000006302", "url": "https://alliancegenome.org/gene/SGD:S000006302#orthology", "database": "AGR" }, { "id": "A1L2F6", "url": "https://omabrowser.org/oma/group/A1L2F6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VRE4-1", "protein_name": "TMEM205-like domain-containing protein", "gene_name": "CG15447", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCHNSGIVEKNNEQQIERYMACGMPSKAVKSVKYTLKKREKKEQQRRDLEKDLHREQQFLEELELSSSASDSSSSSSSSSVTGSDSEDSGVTETVLKSSPSADMTTSPKVISPAPTPRSDLLRFCPRFRKLQQEQQQQMLKEMELQEEEPLATSTPAAALKAQQQRKLSSMEPSMDDALAIGTQMTRQVSERITCLVAKLQASRLYTILTRTTQPAHLIAVCILAFVLMTVGRDLIDPTTTVATAEAAASATAASTRTATGGVMAALVFLGAFATHFGSQIWMTFVSGLSLYFSLPRHVFGQCQQILFPRYFALNAMLSLTMLVVYAKYFLSGWTTSAGIQMGSLALAAGIEVVVRLYLVPPMLQLMHEKYRIEDAIGSGQEVGSLVQGDLVDCPHYQRIHKGFRRIHMTIAIGNMTVMLTTCLQLYFLASKIRLS", "length": 436 }, "evidence": [ { "id": "RGD:1563250", "url": "https://alliancegenome.org/gene/RGD:1563250#orthology", "database": "AGR" }, { "id": "MGI:3045495", "url": "https://alliancegenome.org/gene/MGI:3045495#orthology", "database": "AGR" }, { "id": "HGNC:29631", "url": "https://alliancegenome.org/gene/HGNC:29631#orthology", "database": "AGR" }, { "id": "FB:FBgn0052512", "url": "https://alliancegenome.org/gene/FB:FBgn0052512#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-1692", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-1692#orthology", "database": "AGR" }, { "id": "SGD:S000006302", "url": "https://alliancegenome.org/gene/SGD:S000006302#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A1L2F6", "url": "https://www.uniprot.org/uniprotkb/A1L2F6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A3KNM4-1", "uniprot_ac": "A3KNM4", "uniprot_id": "CS067_DANRE", "mass": { "chemical_mass": 38958.0, "monoisotopic_mass": 38958.0 }, "refseq": { "ac": "NP_001083047", "name": "UPF0575 protein C19orf67 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083047" }, "gene_names": [ { "name": "si:ch211-214c7.5", "type": "recommended", "evidence": [ { "id": "A3KNM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KNM4" } ] }, { "name": "si:ch211-214c7.5", "type": "synonym", "evidence": [ { "id": "NP_001083047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083047" }, { "id": "A3KNM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KNM4" } ] } ], "protein_names": [ { "name": "UPF0575 protein C19orf67 homolog", "type": "recommended", "evidence": [ { "id": "A3KNM4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KNM4/entry#names_and_taxonomy" } ] }, { "name": "UPF0575 protein C19orf67 homolog", "type": "synonym", "evidence": [ { "id": "NP_001083047", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083047" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC133915.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715720 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC133915.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001083047", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083047" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KNM4", "url": "https://www.uniprot.org/uniprotkb/A3KNM4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A3KNM4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061207-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-16", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A3KNM4", "url": "https://alphafold.ebi.ac.uk/entry/A3KNM4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100038798", "url": "https://www.ncbi.nlm.nih.gov/gene/100038798", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100038798", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100038798", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A3KNM4", "url": "https://www.orthodb.org/?gene=A3KNM4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36292", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36292", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36292:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36292:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11771", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11771", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A3KNM4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A3KNM4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001083047", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083047", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TLG1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TLG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TLG1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TLG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KNM4", "url": "https://www.uniprot.org/uniprotkb/A3KNM4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KNM4-1", "url": "https://www.uniprot.org/uniprotkb/A3KNM4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061207-16", "url": "https://zfin.org/ZDB-GENE-061207-16", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MANTEHDELASLLRETNEAEQSLTDQEAITETVEENTTIASSFGDGTFLWDEDPLSGYTPSCEDTRIMEDKISRIEKQLQYLLSKADEFQTQLVWSRNCVQDYGFGNIIPMFLETCQPFFSLLESTARNSNPFCPPQSSNIRMQLLQFSQQLCSRLEQLVLLFASFSFCSLEESDPLSVSHFSIGQCQIDNMKVSIFRYCCPTPFLASSLTGLYKRMRWNVEREIEGEGDGKTYDSAEFYFLCCEDVIEAADDQNEDRSSEGESTETDSESKVSRIWSIGRWVQTYPDPNTEDIIDWVLCSLPCGQYKQLLCLGNEEPSSCTATDCLLGALLSQETHGTFSIIK", "length": 344, "header": "sp|A3KNM4-1|CS067_DANRE Isoform 1 of UPF0575 protein C19orf67 homolog OS=Danio rerio OX=7955 GN= PE=2 SV=1 CANONICAL=A3KNM4-1" }, "isoforms": [ { "isoform_ac": "A0AB32TLG1-1", "url": "https://www.uniprot.org/uniprotkb/A3KNM4/entry#A0AB32TLG1-1", "sequence": { "sequence": "MANTEHDELASLLRETNEAEQSLTDQEAITETVEENTTIASSFGDGTFLWDEDPLSGYTPSCEDTRIMEDKISRIEKQLQYLLSKADEFQTQLVWSRDCVQDYGFGNIIPMFLETCQPFFSLLESTARNSNPFCPPQSSNIRMQLLQFSQQLCSRLEQLVLLFASFSFCSLEESDPLSVSHFSIGQCQIDNMKVSIFRYCCPTPFLASSLTGLYKRMRWNVEREIEEEGDGKTYDSAEFYFLCCEDVIEAADDQNEDRSSEGESTETDSESKVSRIWSIGRWVQTYPDPNTEDIIDWVLCSLPCGQYKQLLCLGNEEPSSCTATDCLLGALLSQETHGTFSIIK", "length": 344, "header": "tr|A0AB32TLG1-1|CS067_DANRE Computationally mapped isoform of UPF0575 protein C19orf67 homolog OS=Danio rerio OX=7955 GN= PE=2 SV=1 CANONICAL=A3KNM4-1" }, "locus": {} }, { "isoform_ac": "A3KNM4-1", "url": "https://www.uniprot.org/uniprotkb/A3KNM4/entry#A3KNM4-1", "sequence": { "sequence": "MANTEHDELASLLRETNEAEQSLTDQEAITETVEENTTIASSFGDGTFLWDEDPLSGYTPSCEDTRIMEDKISRIEKQLQYLLSKADEFQTQLVWSRNCVQDYGFGNIIPMFLETCQPFFSLLESTARNSNPFCPPQSSNIRMQLLQFSQQLCSRLEQLVLLFASFSFCSLEESDPLSVSHFSIGQCQIDNMKVSIFRYCCPTPFLASSLTGLYKRMRWNVEREIEGEGDGKTYDSAEFYFLCCEDVIEAADDQNEDRSSEGESTETDSESKVSRIWSIGRWVQTYPDPNTEDIIDWVLCSLPCGQYKQLLCLGNEEPSSCTATDCLLGALLSQETHGTFSIIK", "length": 344, "header": "sp|A3KNM4-1|CS067_DANRE Isoform 1 of UPF0575 protein C19orf67 homolog OS=Danio rerio OX=7955 GN= PE=2 SV=1 CANONICAL=A3KNM4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100038798", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100038798", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NJJ6-1", "protein_name": "UPF0575 protein C19orf67", "gene_name": "C19orf67", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATEQWFEGSLPLDPGETPPPDALEPGTPPCGDPSRSTPPGRPGNPSEPDPEDAEGRLAEARASTSSPKPLVPRPGPAPPRLSLDTLFSPITQQLRYLLKKADDFQSYLLYSRDQVQKEQLAKAMPTFLQMCEPYFLYLEAAARSIPPIYGPLQELVRKGLLEISQQLTLRLEQLVLMYASFGFVDLEEMNPLSISCFFCGRFSISLSHEVSIFRYCAPTAYTASRFPRYLYKKMRWHLEATPEAPGRGQDSLVDYYFLCYRDTWEDTGQSPANSCPQIQKLWSIGRWVPLGPAEDDLYSWILCPQPLGDYQQLLTIGFEEPTPTLATDLLVQILTGQAGQARPPSAAGPAGWAAQGS", "length": 358 }, "evidence": [ { "id": "RGD:1586683", "url": "https://alliancegenome.org/gene/RGD:1586683#orthology", "database": "AGR" }, { "id": "MGI:1920703", "url": "https://alliancegenome.org/gene/MGI:1920703#orthology", "database": "AGR" }, { "id": "HGNC:34354", "url": "https://alliancegenome.org/gene/HGNC:34354#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-16#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4A283-1", "protein_name": "Similar to human chromosome 19 open reading frame 67", "gene_name": "C19h19orf67", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAESWFAGSLALGPGEAPPSEELGPGPQPYGDPSWSPAGRPEGSTELEPQRAQSMMEAPTSTSSREPLAAELGAAPARLPLDSMFSPITDQLRYLLRKADDFQSYLLYRDRVQKEQLAKAMPTFLTMCEPYFLYLEAAARSVPPIYGALQELVRKGLLEISQQLTLRLEQLVLMYASFGFVDLEETNPLSISCFFCGRFSISPSHDVSIFRYCTPAAYTASHFPRYLYKKMRWNLETTTEASSQGADAHVDYYFLCYRDTWEDAGQGPANSCPQIQKLWSIGRWMPLGPAEDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQILMGQAGPARPPSSAGPAAWAAPAS", "length": 355 }, "evidence": [ { "id": "RGD:1586683", "url": "https://alliancegenome.org/gene/RGD:1586683#orthology", "database": "AGR" }, { "id": "MGI:1920703", "url": "https://alliancegenome.org/gene/MGI:1920703#orthology", "database": "AGR" }, { "id": "HGNC:34354", "url": "https://alliancegenome.org/gene/HGNC:34354#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-16#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CF25-1", "protein_name": "UPF0575 protein C19orf67 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEAPASTSSREPLAAELGPAPARLPLDSMFSPITDQLRYLLRKADDFQSYLLYSRDRVQKEQLAKAMPTFLTMCEPYFLYLEAAARSVPPIYGALQELVRKGLLEISQQLTLRLEQLVLMYASFGFVDLEETNPLSISCFFCGRFSISPSHDVSIFRYCTPAAYTASHFPRYLYKKMRWNLETTTEASSQGADSHVDYYFLCYRDTWEDAGQGPANSCPQIQKLWSIGRWMPLGPAEDDLDSWILCPQPPGDYQQLLTIGFEEPSHVLATDLLVQILLGQAGPARPPSAAGPAAWAAPAS", "length": 301 }, "evidence": [ { "id": "RGD:1586683", "url": "https://alliancegenome.org/gene/RGD:1586683#orthology", "database": "AGR" }, { "id": "MGI:1920703", "url": "https://alliancegenome.org/gene/MGI:1920703#orthology", "database": "AGR" }, { "id": "HGNC:34354", "url": "https://alliancegenome.org/gene/HGNC:34354#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-16#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PLA9-1", "uniprot_ac": "A0A8M9PLA9", "uniprot_id": "A0A8M9PLA9_DANRE", "mass": { "chemical_mass": 76361.0, "monoisotopic_mass": 76361.0 }, "refseq": { "ac": "XP_021327808", "name": "solute carrier family 23 member 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327808" }, "gene_names": [ { "name": "slc23a2", "type": "recommended", "evidence": [ { "id": "A0A8M9PLA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9" } ] }, { "name": "slc23a2", "type": "synonym", "evidence": [ { "id": "XP_021327808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327808" } ] } ], "protein_names": [ { "name": "Solute carrier family 23 member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PLA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9/entry#names_and_taxonomy" } ] }, { "name": "solute carrier family 23 member 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021327808", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327808" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021327808", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327808" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLA9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "slc23a2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090521-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090521-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000017365", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000017365", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100321249", "url": "https://www.ncbi.nlm.nih.gov/gene/100321249", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006043", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006043", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100321249", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100321249", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MVVSMTE", "url": "https://omabrowser.org/oma/group/MVVSMTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A140LG99", "url": "https://www.orthodb.org/?gene=A0A140LG99", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PLA9", "url": "https://www.orthodb.org/?gene=A0A8M9PLA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00860", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00860", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021327808", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327808", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A140LG99", "url": "https://www.uniprot.org/uniprotkb/A0A140LG99", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A140LG99-1", "url": "https://www.uniprot.org/uniprotkb/A0A140LG99-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLA9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090521-3", "url": "https://zfin.org/ZDB-GENE-090521-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MCELDELAGQSVEHEIVLTGRSAVFLPEREWRRAADPQSVEDELSGGMGVGKNTTSKSMDSTTEPGKYEEENKHSAHFYPIPVVNGVVQTAGDQDAEDTQLMAIYAKDSQTEDKCSISDTVDSADSIDAGRIDMIYTIEDTPPWYLCVFLGLQHYLTCFSGTIAVPFLLAEAMCVGFDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLEKWKCNATATLFLNSTELPHTEDIWYPRIREIQGAIIVSSLIEVVIGALGLPGVLLKYIGPLTITPTVTLIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNIHLPLPVYKSKKGWTSYRLQLFKMFPIIMAILVSWFLCFIFTVTDVFPPEKDKYGFYARTDARQGILAAAPWFKIPYPFQWGLPTVTAAGVIGMLSAVVASIIESIGDYYACARLSGAPPPPIHAINRGIFTEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAAFMLLLGMVGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFVDLNSSRNLFVLGFSIFFGLVLPSYLKENPLVTGIVQIDQVLNVLLTTAMFVGGSVAFVLDNTIPGTAEERGIRKMNRGNSSSKRERMESYDLPIGMDFLRRHRIFQYLPISPTFAGYQWSIFTHSCRNRKDESMPAKPELGESGV", "length": 698, "header": "tr|A0A8M9PLA9-1|A0A8M9PLA9_DANRE Isoform 1 of Solute carrier family 23 member 2 isoform X1 OS=Danio rerio OX=7955 GN=slc23a2 PE=3 SV=1 CANONICAL=A0A8M9PLA9-1" }, "isoforms": [ { "isoform_ac": "A0A140LG99-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9/entry#A0A140LG99-1", "sequence": { "sequence": "MGVGKNTTSKSMDSTTEPGKYEEENKHSAHFYPIPVVNGVVQTAGDQDAEDTQLMAIYAKDSQTEDKCSISDTVDSADSIDAGRIDMIYTIEDTPPWYLCVFLGLQHYLTCFSGTIAVPFLLAEAMCVGFDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLEKWKCNATATLFLNSTELPHTEDIWYPRIREIQGAIIVSSLIEVVIGALGLPGVLLKYIGPLTITPTVTLIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNIHLPLPVYKSKKGWTSYRLQLFKMFPIIMAILVSWFLCFIFTVTDVFPPEKDKYGFYARTDARQGILAAAPWFKIPYPFQWGLPTVTAAGVIGMLSAVVASIIESIGDYYACARLSGAPPPPIHAINRGIFTEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAAFMLLLGMVGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFVDLNSSRNLFVLGFSIFFGLVLPSYLKENPLVTGIVQIDQVLNVLLTTAMFVGGSVAFVLDNTIPGTAEERGIRKMNRGNSSSKRERMESYDLPIGMDFLRRHRIFQYLPISPTFAGYQWSIFTHSCRNRKDESMPAKPELGESGV", "length": 651, "header": "tr|A0A140LG99-1|A0A8M9PLA9_DANRE Computationally mapped isoform of Solute carrier family 23 member 2 isoform X1 OS=Danio rerio OX=7955 GN=slc23a2 PE=3 SV=1 CANONICAL=A0A8M9PLA9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PLA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9/entry#A0A8M9PLA9-1", "sequence": { "sequence": "MCELDELAGQSVEHEIVLTGRSAVFLPEREWRRAADPQSVEDELSGGMGVGKNTTSKSMDSTTEPGKYEEENKHSAHFYPIPVVNGVVQTAGDQDAEDTQLMAIYAKDSQTEDKCSISDTVDSADSIDAGRIDMIYTIEDTPPWYLCVFLGLQHYLTCFSGTIAVPFLLAEAMCVGFDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLEKWKCNATATLFLNSTELPHTEDIWYPRIREIQGAIIVSSLIEVVIGALGLPGVLLKYIGPLTITPTVTLIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNIHLPLPVYKSKKGWTSYRLQLFKMFPIIMAILVSWFLCFIFTVTDVFPPEKDKYGFYARTDARQGILAAAPWFKIPYPFQWGLPTVTAAGVIGMLSAVVASIIESIGDYYACARLSGAPPPPIHAINRGIFTEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAAFMLLLGMVGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFVDLNSSRNLFVLGFSIFFGLVLPSYLKENPLVTGIVQIDQVLNVLLTTAMFVGGSVAFVLDNTIPGTAEERGIRKMNRGNSSSKRERMESYDLPIGMDFLRRHRIFQYLPISPTFAGYQWSIFTHSCRNRKDESMPAKPELGESGV", "length": 698, "header": "tr|A0A8M9PLA9-1|A0A8M9PLA9_DANRE Isoform 1 of Solute carrier family 23 member 2 isoform X1 OS=Danio rerio OX=7955 GN=slc23a2 PE=3 SV=1 CANONICAL=A0A8M9PLA9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100321249", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100321249", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0J9YUX7-1", "protein_name": "Solute carrier family 23 member 4", "gene_name": "Slc23a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSAGGSCESPDCMGGDGVLSLHTEGQGKKQDGVQKDPNSNSNLAYGILDSPPWYLCIFLGIQHFLTALGGLVAVPLILAKDLCLQHDPLTQSYLISTIFFVSGICTLLQVFLGVRLPILQGGTFAFVAPSLAMLSLPAWKCPEWTLNASQVNTSSPEFIEEWQKRIRELQGAIMVASCVQMLVGFSGLIGFLMRFIGPLTIAPTISLVALPLFDSAGSDAGIHWGISALTIFLIVLFSQYLKNVMVPVPVYGRRKKCHISRFNLFQVFPVLLALCLSWLFCFVLTVTNTLPESPTAYGYMARTDTKGSVLSQAPWFRFPYPGQWGLPTISLAGVFGIIAGVISSMVESVGDYHACARLVGAPPPPKHAINRGIGIEGLGCLLAGAWGTGNGTTSYSENVGALGITRVGSRMVIVAAGCVLLVMGMFGKIGAAFATIPTPVIGGMFLVMFGIISAVGISNLQYVDMNSSRNLFVFGFSIYCGLAIPNWVNKNPEKLQTGILQLDQVIQVLLTTGMFVGGFLGFVLDNTIPGSLEERGLLAWSKIQEDSEESSKVSKVYGLPWGIGTKFCTSSCTRLLPFWPRLDHHRDEVGVSQLTLCSQTSSGNHLWSATETKM", "length": 615 }, "evidence": [ { "id": "FB:FBgn0037807", "url": "https://alliancegenome.org/gene/FB:FBgn0037807#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AB32TQV8-1", "protein_name": "Solute carrier family 23 member 1 isoform X1", "gene_name": "si:dkey-106n21.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRNAAICWTNSKMWFLKRAAMHLIQQDQKLDTVFKNQGATGSTFELSADSSRDPEKIIAEPQSDSLEEGLDPSPEGNLIYSISDRPPWYLCILLGFQHYILAFGGILAIPLILAEPLCIKENNAAKSQLISTIFFVSGLCTLLQTTLGTRLPILQGGTFTFITPTLAILALPKWRCPDSSADPQVNGTDPASLLVNEDELWKVRIREIQGAILVASLLQLVLGLSGLVGLVLKFIGPLAIAPTINLIGLSLFIQAGQKSGAHWGIAALTVCLIFLFSQYLSKVNLPLIAYKDKKWKVFQYPLFKLFSALFGMCGAWLLCFLLTYFNALPSSPSEYGYKARTDINLSAVKSAAWFYLPYPGQWGVPTVSVSSVLGMMAGVLASTMESIGDYYACARLSGAPPPPTHAINRGIAVEGVGCILAALWGSGNGTTSYSQNIAALGITRVGSRLVLQTAGLLMIILGLFGKFSAVFITIPEPVIGGMFLVMFGMVAAVGISNLQYVDLNSSRNLLILGFSTFSGLVLPTWFHSNPGMINTGVKELDQLIMILFTTHMFIGGFFGFVLDNTIPGTEEERGIKCWRKAVHKGPQMHTTDDSCYNLPFCTNFIAKFRLLQRLPFLPSTATQELRTQM", "length": 629 }, "evidence": [ { "id": "FB:FBgn0037807", "url": "https://alliancegenome.org/gene/FB:FBgn0037807#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1BP61-1", "protein_name": "Solute carrier family 23 member 2", "gene_name": "SLC23A2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MMGIGKNTTSKSMEAGSSAEGKYEDEAKHPSFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTTALLHTEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPSPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRKWKKGVGKGSKSLDGMESYDLPFGMNIIKKYRCFSYLPISPTFAGYTWKGLGKSASSRSSDEDSQATV", "length": 650 }, "evidence": [ { "id": "A0A8M9PLA9", "url": "https://omabrowser.org/oma/group/A0A8M9PLA9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q54NF0-1", "protein_name": "Xanthine/uracil permease family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MFINRNKKDIKNGLKIIINGIKNYFPNYELKQDYSNGVLPDERIPWGPTILLAFQHVLAMFGSTVVGPLLMGFSPNTALLFSGVGTVIFFICTGGKVPSYLGSSFAFIGVVNSATGFVYIAGSNSSNPNIAQASGGILSCGLVYLGISLIVIFVGTKWIEVLTPPVVTGSVVVAIGFHLSTSAIHQVATSAFEAWMALVTVLCVCMVTCYAPGPFKRLPILIGGLSSYLLYFLFGLGEIGPGIDFSGVGNSRWIGSPPITAPVFESTYISLIAPIAIILAAENIGHLKAVSTMTGKNLDYMIGRTFLGDSIACILAGSCGSIGTTTYAENIGVMSITKIFSTLSFLIAAFIAIILGCLPIFGAIIQTIPPGIFGGLSIVLFGITGITGAKLWVEAQVDFSKPRNLLSAGIAIVLGTGMIDVVVQWGNLKIDGIGCATFSSIILYQLLRDDWSKIFKLIISKIKIKNNNNNKTIQKETNTEFQELDNLNNPNTTIDLINSNNNNNNNNNNNNNNNNNKNNNNNNNEDINNNSNTADLHDNNYISN", "length": 544 }, "evidence": [ { "id": "A0A8M9PLA9", "url": "https://omabrowser.org/oma/group/A0A8M9PLA9/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q8GZD4-1", "protein_name": "Nucleobase-ascorbate transporter 3", "gene_name": "NAT3", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVETGHHHQHPPAPAAAGHPPVPSMAMARNMGTTWPPAEQLHHLQYCIHSNPSWHETVVLAFQHYIVMLGTTVLIANTLVSPMGGDPGDKARVIQTILFMSGINTLLQTLIGTRLPTVMGVSFAYVLPVLSIIRDYNNGQFDSEKQRFRHTMRTVQGSLIISSFVNIIIGYGQAWGNLIRIFSPIIVVPVVSVVSLGLFLRGFPLLANCVEIGLPMLILLIITQQYLKHAFSRISMILERYALLVCLAIIWAFAAILTVSGAYNNVSTATKQSCRTDRAFLMSSAPWIRIPYPFQWGTPIFKASHVFGMFGAAIVASAESTGVFFAASRLAGATAPPAHVVSRSIGLQGIGVLLEGIFGSITGNTASVENVGLLGLTRIGSRRVVQVSTFFMIFFSIFGKFGAFFASIPLPIFAGVYCILLGIVVAVGISFIQFTDTNSMRNMYVIGVSLFLSLSIAQYFLANTSRAGYGPVRTAGGWFNDILNTIFASAPLVATILATILDNTLEARHASDDARGIPWWKPFQHRNGDGRNDEFYSMPLRINELMPTRFL", "length": 551 }, "evidence": [ { "id": "A0A8M9PLA9", "url": "https://omabrowser.org/oma/group/A0A8M9PLA9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9EPR4-1", "protein_name": "Solute carrier family 23 member 2", "gene_name": "Slc23a2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMGIGKNTASKSVEAGGSTEGKYEEEAKHSNFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELLEHIWHPRIQEIQGAIIMSSLIEVVIGLLGLPGALLRYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKFQLFKMFPIILAILVSWLLCFIFTVTDVFPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAALMLGLGMVGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLVTGITGIDQILNVLLTTAMFVGGCVAFILDNTIPGTPEERGIKKWKKGVSKGSKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTFAGYTWKGFGKSENSRSSDKDSQATV", "length": 648 }, "evidence": [ { "id": "HGNC:10973", "url": "https://alliancegenome.org/gene/HGNC:10973#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090521-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090521-3#orthology", "database": "AGR" }, { "id": "MGI:1859682", "url": "https://alliancegenome.org/gene/MGI:1859682#orthology", "database": "AGR" }, { "id": "RGD:619876", "url": "https://alliancegenome.org/gene/RGD:619876#orthology", "database": "AGR" }, { "id": "FB:FBgn0037807", "url": "https://alliancegenome.org/gene/FB:FBgn0037807#orthology", "database": "AGR" }, { "id": "A0A8M9PLA9", "url": "https://omabrowser.org/oma/group/A0A8M9PLA9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UGH3-1", "protein_name": "Solute carrier family 23 member 2", "gene_name": "SLC23A2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMGIGKNTTSKSMEAGSSTEGKYEDEAKHPAFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGYDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTDVSVANGTAELLHTEHIWYPRIREIQGAIIMSSLIEVVIGLLGLPGALLKYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPPDSTKYGFYARTDARQGVLLVAPWFKVPYPFQWGLPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGIFGTGNGSTSSSPNIGVLGITKVGSRRVIQCGAALMLALGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIRKWKKGVGKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTFVGYTWKGLRKSDNSRSSDEDSQATG", "length": 650 }, "evidence": [ { "id": "HGNC:10973", "url": "https://alliancegenome.org/gene/HGNC:10973#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090521-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090521-3#orthology", "database": "AGR" }, { "id": "MGI:1859682", "url": "https://alliancegenome.org/gene/MGI:1859682#orthology", "database": "AGR" }, { "id": "RGD:619876", "url": "https://alliancegenome.org/gene/RGD:619876#orthology", "database": "AGR" }, { "id": "FB:FBgn0037807", "url": "https://alliancegenome.org/gene/FB:FBgn0037807#orthology", "database": "AGR" }, { "id": "A0A8M9PLA9", "url": "https://omabrowser.org/oma/group/A0A8M9PLA9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9UHI7-1", "protein_name": "Solute carrier family 23 member 1", "gene_name": "SLC23A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRAQEDLEGRTQHETTRDPSTPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGHDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSLPLNTSHIWHPRIREVQGAIMVSSVVEVVIGLLGLPGALLNYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIILFSQYLRNLTFLLPVYRWGKGLTLLRIQIFKMFPIMLAIMTVWLLCYVLTLTDVLPTDPKAYGFQARTDARGDIMAIAPWIRIPYPCQWGLPTVTAAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAAIMLVLGTIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLESNPGAINTGILEVDQILIVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSDMSSSLKSYDFPIGMGIVKRITFLKYIPICPVFKGFSSSSKDQIAIPEDTPENTETASVCTKV", "length": 598 }, "evidence": [ { "id": "FB:FBgn0037807", "url": "https://alliancegenome.org/gene/FB:FBgn0037807#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VH02-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG6293", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MELNNVTIEDATDASKSYSQAANTPPSNEKPKPQLLYAINDNPPWYLSIFLAFQHYLTMIGAIVSIPFILTPALCMSDEDANRGIIISTMIFVTGIVTYFQATWGVRLPIVQGGTISFLVPTLAILALPQWKCPEQAVMDAMDEAEREELWQVRMRELSGAIAVSAMVQVILGYTGLVGKILKYVTPLTIVPTVSLVGLTLFEHAAETASKHWGIAVGTTGMLTLFSQIMSNVPVPILAYRKGHGLEIRQFQLFRLFPVLLTIMIMWGLCGILTATDVFPPSHPSRTDVRLNVLTSAKWFYVPYPGQFGWPSVTLSGVLGMLAGVLACTVESLSYYPTVSQMSGAHSPPLHAINRGIGTEGFGTVLAGLWGAGNGTNTFGENVGAIGVTKIGSRRVIQWAALIMVLQGVIGKFGAIFILIPDSVVGGIFCVMFGMIIAFGLSTLQYVDLRSARNLYILGLSIFFPMVLCRWMQKNPGAIDTGNKTVDSTLSVLLGTTILVGGVLGCLLDNIIPGTPEERGLIDWANEMPLGDDNVNDGTATDYDFPLGMDAIRRWKWTYYIPFMPTYKLQKQS", "length": 573 }, "evidence": [ { "id": "HGNC:10973", "url": "https://alliancegenome.org/gene/HGNC:10973#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090521-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090521-3#orthology", "database": "AGR" }, { "id": "MGI:1859682", "url": "https://alliancegenome.org/gene/MGI:1859682#orthology", "database": "AGR" }, { "id": "RGD:619876", "url": "https://alliancegenome.org/gene/RGD:619876#orthology", "database": "AGR" }, { "id": "FB:FBgn0037807", "url": "https://alliancegenome.org/gene/FB:FBgn0037807#orthology", "database": "AGR" }, { "id": "A0A8M9PLA9", "url": "https://omabrowser.org/oma/group/A0A8M9PLA9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WTW7-1", "protein_name": "Solute carrier family 23 member 1", "gene_name": "Slc23a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKAQEDPGSSKQHECPDSAGTSTRDQQAPLPAEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGRDQHMISQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKAILALERWKCPPEEEIYGNWSMPLNTSHIWHPRIREVQGAIMVSSVVEVVIGLLGLPGALLSYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRIQIFKMFPIVLAIMTVWLLCYVLTLTDVLPADPTVYGFQARTDARGDIMAISPWIRIPYPCQWGLPTVTVAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGVCCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIMLILGAIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLDSNPGAINTGVPEVDQILTVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSETLASLKSYDFPFGMGMVKRTTFFRYIPICPVFRGFSKTENQPAVLEDAPDNTETGSVCTKV", "length": 604 }, "evidence": [ { "id": "FB:FBgn0037807", "url": "https://alliancegenome.org/gene/FB:FBgn0037807#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9WTW8-1", "protein_name": "Solute carrier family 23 member 2", "gene_name": "Slc23a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMGVGKNTSKSVEVGGSTEGKYEEEAKRPDFFTLPVVINGGATSSGEQDNEDTELMAIYTTENGIAEKSSLAETLDSTGSLDPQRSDMIYTIEDVPPWYLCIFLGLQHYLTCFSGTIAVPFLLADAMCVGDDQWATSQLIGTIFFCVGITTLLQTTFGCRLPLFQASAFAFLAPARAILSLDKWKCNTTEITVANGTAELLEHIWHPRIQEIQGAIIMSSLIEVVIGLLGLPGALLRYIGPLTITPTVALIGLSGFQAAGERAGKHWGIAMLTIFLVLLFSQYARNVKFPLPIYKSKKGWTAYKLQLFKMFPIILAILVSWLLCFIFTVTDVFPSNSTDYGYYARTDARKGVLLVAPWFKVPYPFQWGMPTVSAAGVIGMLSAVVASIIESIGDYYACARLSCAPPPPIHAINRGIFVEGLSCVLDGVFGTGNGSTSSSPNIGVLGITKVGSRRVIQYGAALMLGLGMIGKFSALFASLPDPVLGALFCTLFGMITAVGLSNLQFIDLNSSRNLFVLGFSIFFGLVLPSYLRQNPLVTGITGIDQVLNVLLTTAMFVGGCVAFILDNTIPGTPEERGIKKWKKGVSKGNKSLDGMESYNLPFGMNIIKKYRCFSYLPISPTFAGYTWKGFGKSENRRSSDKDSQATV", "length": 647 }, "evidence": [ { "id": "HGNC:10973", "url": "https://alliancegenome.org/gene/HGNC:10973#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090521-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090521-3#orthology", "database": "AGR" }, { "id": "MGI:1859682", "url": "https://alliancegenome.org/gene/MGI:1859682#orthology", "database": "AGR" }, { "id": "RGD:619876", "url": "https://alliancegenome.org/gene/RGD:619876#orthology", "database": "AGR" }, { "id": "FB:FBgn0037807", "url": "https://alliancegenome.org/gene/FB:FBgn0037807#orthology", "database": "AGR" }, { "id": "A0A8M9PLA9", "url": "https://omabrowser.org/oma/group/A0A8M9PLA9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Z2J0-1", "protein_name": "Solute carrier family 23 member 1", "gene_name": "Slc23a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTPEDPGSPKQHEVVDSAGTSTRDRQAPLPTEPKFDMLYKIEDVPPWYLCILLGFQHYLTCFSGTIAVPFLLAEALCVGRDQHMVSQLIGTIFTCVGITTLIQTTVGIRLPLFQASAFAFLVPAKSILALERWKCPSEEEIYGNWSMPLNTSHIWHPRIREVQGAIMVSSMVEVVIGLMGLPGALLSYIGPLTVTPTVSLIGLSVFQAAGDRAGSHWGISACSILLIVLFSQYLRNLTFLLPVYRWGKGLTLFRVQIFKMFPIVLAIMTVWLLCYVLTLTDVLPADPTVYGFQARTDARGDIMAISPWIRIPYPCQWGLPTVTVAAVLGMFSATLAGIIESIGDYYACARLAGAPPPPVHAINRGIFTEGICCIIAGLLGTGNGSTSSSPNIGVLGITKVGSRRVVQYGAGIMLILGAIGKFTALFASLPDPILGGMFCTLFGMITAVGLSNLQFVDMNSSRNLFVLGFSMFFGLTLPNYLDSNPGAINTGIPEVDQILTVLLTTEMFVGGCLAFILDNTVPGSPEERGLIQWKAGAHANSETSASLKSYDFPFGMGMVKRTTFFRYIPICPVFRGFSKKTQNQPPVLEDTPDNIETGSVCTKV", "length": 605 }, "evidence": [ { "id": "FB:FBgn0037807", "url": "https://alliancegenome.org/gene/FB:FBgn0037807#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLA9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9" } ], "pmid": "" }, { "name": "apical plasma membrane", "id": "GO:0016324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016324", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLA9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transmembrane transporter activity", "id": "GO:0022857", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022857", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLA9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9" } ], "pmid": "" }, { "name": "L-ascorbate:sodium symporter activity", "id": "GO:0008520", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008520", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLA9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9" } ], "pmid": "" }, { "name": "L-ascorbic acid transmembrane transporter activity", "id": "GO:0015229", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015229", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLA9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "L-ascorbic acid transmembrane transport", "id": "GO:0015882", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015882", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLA9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 241, "end_pos": 243, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 233, "end_pos": 235 }, { "start_pos": 241, "end_pos": 243 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 556, "end_pos": 558 }, { "start_pos": 632, "end_pos": 634 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PQY2-1", "uniprot_ac": "A0A8M9PQY2", "uniprot_id": "A0A8M9PQY2_DANRE", "mass": { "chemical_mass": 17321.0, "monoisotopic_mass": 17321.0 }, "refseq": { "ac": "XP_021329423", "name": "uncharacterized protein si:dkey-12l12.1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329423" }, "gene_names": [ { "name": "si:dkey-12l12.1", "type": "recommended", "evidence": [ { "id": "A0A8M9PQY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQY2" } ] }, { "name": "si:dkey-12l12.1", "type": "synonym", "evidence": [ { "id": "XP_021329423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329423" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkey-12l12.1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PQY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQY2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkey-12l12.1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021329423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329423" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329423" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQY2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-12l12.1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQY2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-232", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-232", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "566480", "url": "https://www.ncbi.nlm.nih.gov/gene/566480", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:566480", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566480", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PQY2", "url": "https://www.orthodb.org/?gene=A0A8M9PQY2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_021329423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PQY2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TP93", "url": "https://www.uniprot.org/uniprotkb/A0AB32TP93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TP93-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TP93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-232", "url": "https://zfin.org/ZDB-GENE-091204-232", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MATVLWICLLFLQGCLLINSLDCTGKSLECAGTQVTEAKIKDEPFLTLVRERRQAQHTQQPGSYSVKGSPNTLIQIDRSRRHLNASKKKPRPRIGSYSLLSHNSETNPLQVVRLSKHNEDLSHRNMSGLKSSKKRSRRSAPKRKKNVRNKTCS", "length": 153, "header": "tr|A0A8M9PQY2-1|A0A8M9PQY2_DANRE Isoform 1 of Uncharacterized protein si:dkey-12l12.1 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-12l12.1 PE=4 SV=1 CANONICAL=A0A8M9PQY2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PQY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQY2/entry#A0A8M9PQY2-1", "sequence": { "sequence": "MATVLWICLLFLQGCLLINSLDCTGKSLECAGTQVTEAKIKDEPFLTLVRERRQAQHTQQPGSYSVKGSPNTLIQIDRSRRHLNASKKKPRPRIGSYSLLSHNSETNPLQVVRLSKHNEDLSHRNMSGLKSSKKRSRRSAPKRKKNVRNKTCS", "length": 153, "header": "tr|A0A8M9PQY2-1|A0A8M9PQY2_DANRE Isoform 1 of Uncharacterized protein si:dkey-12l12.1 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-12l12.1 PE=4 SV=1 CANONICAL=A0A8M9PQY2-1" }, "locus": {} }, { "isoform_ac": "A0AB32TP93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQY2/entry#A0AB32TP93-1", "sequence": { "sequence": "MATVLWICLLFLQGCLLINSLDCTGKSLECAGTQVTEAKVRERRQAQHTQQPGSYSVKGSPNTLIQIDRSRRHLNASKKKPRPRIGSYSLLSHNSETNPLQVVRLSKHNEDLSHRNMSGLKSSKKRSRRSAPKRKKNVRNKTCS", "length": 144, "header": "tr|A0AB32TP93-1|A0A8M9PQY2_DANRE Computationally mapped isoform of Uncharacterized protein si:dkey-12l12.1 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-12l12.1 PE=4 SV=1 CANONICAL=A0A8M9PQY2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:566480", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566480", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 125, "end_pos": 127 }, { "start_pos": 149, "end_pos": 151 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"ac": "NP_957433", "name": "3-dehydrosphinganine reductase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957433" }, "gene_names": [ { "name": "kdsr", "type": "recommended", "evidence": [ { "id": "A0AAR9J7U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAR9J7U1" } ] }, { "name": "fvt1", "type": "synonym", "evidence": [ { "id": "NP_957433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957433" }, { "id": "A0AAR9J7U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAR9J7U1" } ] }, { "name": "kdsr", "type": "synonym", "evidence": [ { "id": "NP_957433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957433" } ] }, { "name": "unm_muz106", "type": "synonym", "evidence": [ { "id": "NP_957433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957433" }, { "id": "A0AAR9J7U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAR9J7U1" } ] }, { "name": "zgc:55947", "type": "synonym", "evidence": [ { "id": "NP_957433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957433" }, { "id": "A0AAR9J7U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAR9J7U1" } ] } ], "protein_names": [ { "name": "3-dehydrosphinganine reductase", "type": "recommended", "evidence": [ { "id": "A0AAR9J7U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAR9J7U1/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.102", "type": "synonym", "evidence": [ { "id": "A0AAR9J7U1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AAR9J7U1/entry#names_and_taxonomy" } ] }, { "name": "3-dehydrosphinganine reductase", "type": "synonym", "evidence": [ { "id": "NP_957433", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957433" } ] }, { "name": "follicular lymphoma variant translocation 1", "type": "synonym", "evidence": [ { "id": "NP_957433", "database": 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The reference sequence was derived from EH548401.1 and JBMGRA010000002.1. On Feb 19, 2016 this sequence version replaced NP_957433.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_957433", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957433" } ] }, { "annotation": "3-ketodihydrosphingosine reductase mutation induces steatosis and hepatic injury in zebrafish. Erratum:[Sci Rep. 2020 Jul 15;10(1):11971. doi: 10.1038/s41598-020-67912-8. 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"annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322566" } ] } ], "disease": [ { "disease_id": "DOID:0080326", "recommended_name": { "id": "DOID:0080326", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080326", "name": "familial hypertrophic cardiomyopathy", "description": "A hypertrophic cardiomyopathy that is characterized by thickening of the heart muscle and has_material_basis_in autosomal dominant inheritance of one or more gene mutations." }, "synonyms": [ { "id": "MONDO:0008647", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008647", "name": "hypertrophic cardiomyopathy 1", "description": "Any hypertrophic cardiomyopathy in which the cause of the disease is a mutation in the MYH7 gene." }, { "id": "MONDO:0008647", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008647", "name": "CMH1", "description": "" }, { "id": "MONDO:0008647", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008647", "name": "MYH7 hypertrophic cardiomyopathy", "description": "" }, { "id": "MONDO:0008647", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008647", "name": "cardiomyopathy, familial hypertrophic, Autosomal dominant, Digenic dominant", "description": "" }, { "id": "MONDO:0008647", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008647", "name": "cardiomyopathy, familial hypertrophic, type 1", "description": "" }, { "id": "MONDO:0008647", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008647", "name": "cardiomyopathy, hypertrophic, 1, Autosomal dominant, Digenic dominant", "description": "" }, { "id": "MONDO:0008647", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008647", "name": "cardiomyopathy, hypertrophic, 1, digenic, Autosomal dominant, Digenic dominant", "description": "" }, { "id": "MONDO:0008647", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008647", "name": "hypertrophic cardiomyopathy 1", "description": "" }, { "id": "MONDO:0008647", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008647", "name": "hypertrophic cardiomyopathy caused by mutation in MYH7", "description": "" }, { "id": "MONDO:0008647", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008647", "name": "hypertrophic cardiomyopathy type 1", "description": "" }, { "id": "MONDO:0008647", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008647", "name": "cardiomyopathy, familial hypertrophic, 1", "description": "" }, { "id": "MIM:192600", "resource": "MIM", "url": "https://www.omim.org/entry/192600", "name": "Cardiomyopathy, familial hypertrophic", "description": "Cardiomyopathy, familial hypertrophic" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080326", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080326" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fhod3b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081028-61", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081028-61", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PK03", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PK03", "database": "AlphaFoldDB", "categories": [] }, { "id": "570795", "url": "https://www.ncbi.nlm.nih.gov/gene/570795", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014767", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014767", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056771", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056771", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570795", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570795", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PK03", "url": "https://www.orthodb.org/?gene=A0A8M9PK03", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45920", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45920", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45920:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45920:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18382", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18382", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24959", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24959", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322566", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322566", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9NZN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9NZN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P8A0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8A0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P8A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P8A0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDK4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PDK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PDK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PK03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PK03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T566", "url": "https://www.uniprot.org/uniprotkb/A0AB32T566", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T566-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T566-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TA77", "url": "https://www.uniprot.org/uniprotkb/A0AB32TA77", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TA77-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TA77-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHL5", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHL5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHL5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHL8", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHL8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHM1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHM3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHM3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHM7", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHM7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHT8", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHT8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHU0", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHU0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHU3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHU3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHU6", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHU6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHU7", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHU7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHV2", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHV2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHV2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHV2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHV6", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHV6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHW2", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHW2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHW2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHW2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081028-61", "url": "https://zfin.org/ZDB-GENE-081028-61", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MATFACRVQFLDDTDPFNSTNFPEPTRPPHFTFREDIPLINQIAGVHRLLKAPHKLDDCALQLSHNGSYLDLESTLAEQKDELEGFQEDGGRGKKHSIVLRTQLSVRVHACIEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISEREDEEEEEEKDEEFQKAALSRQASGSCVASTVEDASSLCLPLRCMVNFIPNAADTENAEKPRNRSGIRVIHKAPMSSPPFTPDFVPPLSPRLSSWSSVRSLGAVPSQGSSVTSSASTSPGEEPQSPVLPLLSSNLLHTCPEDLDEVFVGTLQGQDPDKHCSLSDVSYPNTPCSSCGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESDEEEEDESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1692, "header": "tr|A0A8M9PK03-1|A0A8M9PK03_DANRE Isoform 1 of FH1/FH2 domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "isoforms": [ { "isoform_ac": "A0A8M9NZN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0A8M9NZN4-1", "sequence": { "sequence": "MATFACRVQFLDDTDPFNSTNFPEPTRPPHFTFREDIPLINQIAGVHRLLKAPHKLDDCALQLSHNGSYLDLESTLAEQKDELEGFQEDGGRGKKHSIVLRTQLSVRVHACIEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISEREDEEEEEEKDEEFQKAALSRQASGSLSDVSYPNTPCSSCGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESDEEEEDESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1557, "header": "tr|A0A8M9NZN4-1|A0A8M9PK03_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P8A0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0A8M9P8A0-1", "sequence": { "sequence": "MATFACRVQFLDDTDPFNSTNFPEPTRPPHFTFREDIPLINQIAGVHRLLKAPHKLDDCALQLSHNGSYLDLESTLAEQKDELEGFQEDGGRGKKHSIVLRTQLSVRVHACIEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISESLSDVSYPNTPCSSCGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESDEEEEDESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1532, "header": "tr|A0A8M9P8A0-1|A0A8M9PK03_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PDK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0A8M9PDK4-1", "sequence": { "sequence": "MATFACRVQFLDDTDPFNSTNFPEPTRPPHFTFREDIPLINQIAGVHRLLKAPHKLDDCALQLSHNGSYLDLESTLAEQKDELEGFQEDGGRGKKHSIVLRTQLSVRVHACIEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISESNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESDEEEEDESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1516, "header": "tr|A0A8M9PDK4-1|A0A8M9PK03_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PK03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0A8M9PK03-1", "sequence": { "sequence": "MATFACRVQFLDDTDPFNSTNFPEPTRPPHFTFREDIPLINQIAGVHRLLKAPHKLDDCALQLSHNGSYLDLESTLAEQKDELEGFQEDGGRGKKHSIVLRTQLSVRVHACIEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISEREDEEEEEEKDEEFQKAALSRQASGSCVASTVEDASSLCLPLRCMVNFIPNAADTENAEKPRNRSGIRVIHKAPMSSPPFTPDFVPPLSPRLSSWSSVRSLGAVPSQGSSVTSSASTSPGEEPQSPVLPLLSSNLLHTCPEDLDEVFVGTLQGQDPDKHCSLSDVSYPNTPCSSCGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESDEEEEDESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1692, "header": "tr|A0A8M9PK03-1|A0A8M9PK03_DANRE Isoform 1 of FH1/FH2 domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AB32T566-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AB32T566-1", "sequence": { "sequence": "MATFACRVQFLDDTDPFNSTNFPEPTRPPHFTFREDIPLINQIAGVHRLLKAPHKLDDCALQLSHNGSYLDLESTLAEQKDELEGFQEDGGRGKKHSIVLRTQLSVRVHACIEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISEREDEEEEEEKDEEFQKAALSRQASGSCVASTVEDASSLCLPLRCMVNFIPNAADTENAEKPRNRSGIRVIHKAPMSSPPFTPDFVPPLSPRLSSWSSVRSLGAVPSQGSSVTSSASTSPGEEPQSPVLPLLSSNLLHTCPEDLDEVFVGTLQGQDPDKHCSLSDVSYPNTPCSSCGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1684, "header": "tr|A0AB32T566-1|A0A8M9PK03_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AB32TA77-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AB32TA77-1", "sequence": { "sequence": "MATFACRVQFLDDTDPFNSTNFPEPTRPPHFTFREDIPLINQIAGVHRLLKAPHKLDDCALQLSHNGSYLDLESTLAEQKDELEGFQEDGGRGKKHSIVLRTQLSVRVHACIEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISEREDEEEEEEKDEEFQKAALSRQASGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESDEEEEDESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1541, "header": "tr|A0AB32TA77-1|A0A8M9PK03_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHL5-1", "sequence": { "sequence": "MSQREIAGRNNTNELEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISESLSDVSYPNTPCSSCGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESDEEEEDESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1435, "header": "tr|A0AC58HHL5-1|A0AC58HHL5_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X16 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHL8-1", "sequence": { "sequence": "MSQREIAGRNNTNELEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISESNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1411, "header": "tr|A0AC58HHL8-1|A0AC58HHL8_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X19 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHM1-1", "sequence": { "sequence": "MSQREIAGRNNTNELEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISEREDEEEEEEKDEEFQKAALSRQASGSLSDVSYPNTPCSSCGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1452, "header": "tr|A0AC58HHM1-1|A0AC58HHM1_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X13 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHM3-1", "sequence": { "sequence": "MSQREIAGRNNTNELEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISEREDEEEEEEKDEEFQKAALSRQASGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1436, "header": "tr|A0AC58HHM3-1|A0AC58HHM3_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X15 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHM7-1", "sequence": { "sequence": "MSQREIAGRNNTNELEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISESLSDVSYPNTPCSSCGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1427, "header": "tr|A0AC58HHM7-1|A0AC58HHM7_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X17 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHT8-1", "sequence": { "sequence": "MSQREIAGRNNTNELEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISESNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESDEEEEDESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1419, "header": "tr|A0AC58HHT8-1|A0AC58HHT8_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X18 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHU0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHU0-1", "sequence": { "sequence": "MSQREIAGRNNTNELEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISEREDEEEEEEKDEEFQKAALSRQASGSCVASTVEDASSLCLPLRCMVNFIPNAADTENAEKPRNRSGIRVIHKAPMSSPPFTPDFVPPLSPRLSSWSSVRSLGAVPSQGSSVTSSASTSPGEEPQSPVLPLLSSNLLHTCPEDLDEVFVGTLQGQDPDKHCSLSDVSYPNTPCSSCGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1587, "header": "tr|A0AC58HHU0-1|A0AC58HHU0_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X3 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHU3-1", "sequence": { "sequence": "MATFACRVQFLDDTDPFNSTNFPEPTRPPHFTFREDIPLINQIAGVHRLLKAPHKLDDCALQLSHNGSYLDLESTLAEQKDELEGFQEDGGRGKKHSIVLRTQLSVRVHACIEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISESNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1508, "header": "tr|A0AC58HHU3-1|A0AC58HHU3_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X11 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHU6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHU6-1", "sequence": { "sequence": "MATFACRVQFLDDTDPFNSTNFPEPTRPPHFTFREDIPLINQIAGVHRLLKAPHKLDDCALQLSHNGSYLDLESTLAEQKDELEGFQEDGGRGKKHSIVLRTQLSVRVHACIEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISEREDEEEEEEKDEEFQKAALSRQASGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1533, "header": "tr|A0AC58HHU6-1|A0AC58HHU6_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X7 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHU7-1", "sequence": { "sequence": "MATFACRVQFLDDTDPFNSTNFPEPTRPPHFTFREDIPLINQIAGVHRLLKAPHKLDDCALQLSHNGSYLDLESTLAEQKDELEGFQEDGGRGKKHSIVLRTQLSVRVHACIEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISESLSDVSYPNTPCSSCGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1524, "header": "tr|A0AC58HHU7-1|A0AC58HHU7_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X9 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHV2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHV2-1", "sequence": { "sequence": "MSQREIAGRNNTNELEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISEREDEEEEEEKDEEFQKAALSRQASGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESDEEEEDESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1444, "header": "tr|A0AC58HHV2-1|A0AC58HHV2_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X14 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHV6-1", "sequence": { "sequence": "MATFACRVQFLDDTDPFNSTNFPEPTRPPHFTFREDIPLINQIAGVHRLLKAPHKLDDCALQLSHNGSYLDLESTLAEQKDELEGFQEDGGRGKKHSIVLRTQLSVRVHACIEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISEREDEEEEEEKDEEFQKAALSRQASGSLSDVSYPNTPCSSCGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1549, "header": "tr|A0AC58HHV6-1|A0AC58HHV6_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X5 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHW2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03/entry#A0AC58HHW2-1", "sequence": { "sequence": "MSQREIAGRNNTNELEKLYNSTGRELRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGLIGHNETVQWLYTLVGSKFRLVVKTAMKLLLVFVEYTESNAPLLIQAVNSVDTKQGSKPWSNAMEILDEKDGMDTELLVYAMTLINKTLAGLPDQDSFYDVVDSLEEQNMEAVAQRHISRKGTDLDLVEQFNIYEATLRHEDGDDEAQSPPSGHKCRRRASVGATPERRGLERRRSRRHSLQNGKGHTSAPTSPCHSHTPNILSFNSQRIEDISEREDEEEEEEKDEEFQKAALSRQASGSLSDVSYPNTPCSSCGSNGNASTYPGRSSGVSSALSTPYNRFGPSGGPSADSKADRPTLGGLLTSSYRQHQESLNAERERRRLEREERLQRIEREERNRFNRDYADKREEVRHAREERYKQVERLTAEEKERERPRTRGRTEITLSLSSRTSSSSLSRSVTPLTVDAQEETRPVSHTAQGTVTEKSCTVQTAVVRSLSEPPSASPPVSPSQPEEQQRPVDPSDIILSLSPTNSEPERTEKGEKKEDAEAEECEETVVGEVQDEKKEEPEGNFEDETNVTGAEDCEREKTLDREVEESAILSEKEKQNEELNEKDNCSASSISSASSTLEREEREEKHVSDSNSGQWADCINTADNNDQCNKVLNSKRFMLDMLYAQNKEGEEDEKEKENENEKCLGQDSTVTSLASRISTLESHRQTCEDNLKKLEVEHLENQGSVRAVAEKFGDLVKGMLSPHDLENCGKEKQQTQEKPPPAPSPAPPKKESDHIWDQLMATPRELRIKELDFTDLGEEDDVDILDVGNMIGSGDLTPPPPPPPCLPNLPPPPPLFGCPLPPPVPGMMMPPPPPFLASKPPAQLGSPQLSRGEPPLFQKKKKTIRLFWNEVRPIDWQYTNHKRCKESLWSKLDPIKLDTAKLENLFETKSKELPVTKKTAADGKRQEIIILDSKRSNAINIGLTVLPPPRTIKTAILNFDEYALSKEGIEKILTMIPTEEETQKIQEAQLANPDTPLGSAEQFLLILSSISELSARLQLWAFKMDYDALEKEVAEPLQDLKEGMDQLEKNKTLRSILSTLLAIGNFLNGTNAKGFELSYLEKVPEVKDTVHKQSLLHHVCSIVVEKFPESTDLYSEIGAITRSAKVDFDQLQENLCQMERRCKASWDHLKVISKHEIKPALKQRMSDFLKDCAGRIIILKIVHRRIINRFHSFLLFLGHPPYAIREVSVHRFSKILSEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITESDEEEEDESGKFAGSPMEGQECQPQGLGYTEDVTEHEQMTAVLCTSLQGGDSPSSVLPGLRTRTRATRGHTALLSTANEDTSNCTNDTADEIMERIVKSATQGPSQRTQPRERRRSRANRKSLRRTLKNGLTPEEAQALGLASGSEMQV", "length": 1460, "header": "tr|A0AC58HHW2-1|A0AC58HHW2_DANRE Computationally mapped isoform of FH1/FH2 domain-containing protein 3 isoform X12 OS=Danio rerio OX=7955 GN=fhod3b PE=3 SV=1 CANONICAL=A0A8M9PK03-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 349, "start_aa": "Thr", "end_pos": 349, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr349", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:570795", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570795", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZ38-1", "protein_name": "Formin homology 2 domain containing 1", "gene_name": "Fhod1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSAQIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRVNAILEKLYGSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLFIQAVNAVASNTGTLPWANLVSILEEKNGVDPELLVYTVTLINKTLAALPDQDSFYDVTDAFEQQGMEALVQRLLGTAGTDVDLRTQLTLYESALRLEDGDMEEAAAAAAAGGRRERRKPSSEEGKRSRRSLEGGGCPVRTPEPGPTGSASPVGSASFTDSTSPTSSAFSPTGPASGLHTSVNLFPTISVGPSVDTSCERSVYKARFLENVAAAETEKQAALAQGRAETLAGATVDETDESSGTRELWDSSEPASAPRPPQSPVSPIVLRTQRSLEPEPKEPVSPRSPKTEPVQELPTHVPKLCIGDLDFSDLGEDEDQDTLNVESVEAGKASLVLSLPPSSFSGGPPPPPPPPPPIIVSCPPPPPPPPPPIMGSCLPPPPLAAPFPHSALDGPRHPTKRKTVKLFWRELKPTGSPGCSRSRFGPCPTLWASLEPVSVDTARLEHLFESRAKDVLPTKKAGEGRRTMTIVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGPAENFLMTLASIGGLAARLQLWAFKLDYESMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSEVKDTVRRQSLLYHLCSLVLQTRPDSSDLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELSPALRARLTHFLAQCTRRVAMLRVVHRRVCNRFHAFLLYLGYTAQAAREVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERNKTRGRMITETEKFSGVAGEVPSNLSVPVAVGSGPGRGDADNHASMKSLLTSRPEDATHSRRSRGMVQSSSPVTHTTVGPFTASPEETAASGLPSDTSDEIMDLLVQSVTKSSPRALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAPGLEV", "length": 1180 }, "evidence": [ { "id": "FB:FBgn0266084", "url": "https://alliancegenome.org/gene/FB:FBgn0266084#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PNT9-1", "protein_name": "FH1/FH2 domain-containing protein 3 isoform X1", "gene_name": "fhod3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSFVCRVQFLDDTDPFNSTNFPEPTRPPVYTFREDIPVINQIAGVHRLLKAPHKLDDCALQLSHNGVYLDLESTLDEQRDELEGFQQDDCAGRGKKHSVILRTQLSVRVHACIEKLYNSNGRDLRRALFSLKQIFQDDKDLVHEFVMAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGVIGHNESIQWLYQLIGSKFRLVVKTSLKLLLVFVEYSESNAALLIQAIDTVDNKRGCKSWSNAMEILAEKDGVDTELLVYVMTLINKTLAALPDQDSFYDMVDVLEEQGMESVSQRYLGRKGTDLDLLEQLNIYEATLRHEDGDEDGLPPSCGRRDRRRSSVGGERRGLERRRSRRHSLGRPGHASPLSPASPHRTNIKLMNGQDERTLLKHECLPVIEEDEDEEETPVTESGSDNNDDDDDEGGINPSHHSVISGSGKSSLCNKHTTEEEEKKRATSSALPPADSAQPSVLANLLARRRSSVTVPSTNQISPPQRPLDRLPYLPHSPFFLFSYDMEEQEEKPDEKNSRSLSAVGSPSTPTKQNERPALGGLLSSSYRQHQESLAAEREKRRVQREERLQRIEREERNRHSRDYVSNMEEARHAREERFKTAERLAAEEFERERQRSAPRGLPTDTCQSSRSATPSSVTSQEEQDTPIASYPPSEPDTNDLEPEAEADLEPEEKKPTEEAEEEVEEEVEEEVEEGVSAEPEVSAAEEQVAEEEEESEREAPDGEAEDSGILSDKERQNEEVNEKDNCSASSISSASSTLEREDRLNAGAADTGQWNVNEQRHKILDSKLFMLDMLYSQSKKPCEEDEDEDEELAEDKEADGEEKEPDEDSATAPDENTEADKKQETQSNVRAFAERFGDVVKGLTSPPIELQDLPPPPPPPPPKKESDCIWDQLMASPRDLRIGDIDFTDLGDEDDQDVLDSGSLYSSGDLQAPPPPPPPCPFNLPAPPPMFGCPPPPPVFSIRVPPPPPCFSNQAPPPPEMKAELPLFQKKKKTIRLFWSEVQPADWIYRNHKRSQESLWSRLEPVKIDTAKLEHLFESKSKEMPVAKKAAADGKRPEIIVLDSKRSNSINIGLTVLPPPRTIKTAIVNFDEYALNKEGIEKILTMIPTAEETQRIQEAQLANPDVPLGSAEQFLLTLSSISELSARLQLWAFKLDYEATEKEVAEPLQDLKEGMDQLEKNKTLRYILSTLLAIGNFLNGSNAKGFDLNYLEKVPEVKDTVHKQSLLHHVCSAVLENCSDTTDLYSEIGAITRSAKVDFEQLQENLTLMERRCKASWDHLKVIAKHEMKPVLKQKMSDFLKECAERIIILKIVHRRIMNRFHSFLLFLGQPAYSVREISVTRFSKIISEFALEYRTTRERVLQQKQKRADHRERNKTRGKMITDVNTQTDDEEDSEAAGRVCVSSSSSAPPAGPQMQVQPQPQPSQPQGLCDAEDAAEHQQMTAVLKTRDLRTRTRTRATQGRSAWAPVNEESQINTEDAADEIMERIVRSATQSPRERAQPRERRRSRANRKSLRRTLKGGLTPEEAQALGFDTSDMPV", "length": 1557 }, "evidence": [ { "id": "RGD:2322319", "url": "https://alliancegenome.org/gene/RGD:2322319#orthology", "database": "AGR" }, { "id": "HGNC:26178", "url": "https://alliancegenome.org/gene/HGNC:26178#orthology", "database": "AGR" }, { "id": "MGI:1925847", "url": "https://alliancegenome.org/gene/MGI:1925847#orthology", "database": "AGR" }, { "id": "FB:FBgn0266084", "url": "https://alliancegenome.org/gene/FB:FBgn0266084#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QHW7-1", "protein_name": "FH1/FH2 domain-containing protein 1 isoform X1", "gene_name": "fhod1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATITCRVQYLEDSDPFVCSNFPEPRRPPQYDFNEHLPLNEQIAGVHKLLEAPLKLEECALQLASNGNYLDLDSSLAEQRDDVEQLYDDVEKGKKPILILRTQLSVRVHSILEKLYNSHGPELRRSLFSLKQLFQDDKDLVPEFVISEGLTCFIKVGAEADHNYQNYILRALSQIMLFVDGMNGIVNHNETVQWLYTLCGSLSRLVVKTALKLLIVFVEYTESNSPLLIQAVNIVDGKRGVKPWTILIDILSAKNGSDTELLIYTMTLINKTLAALPDQDSFYDVTDCLEQLEMESIIQKHMTSSGTEGDLKQQFTIYEKALKCEDGEMDETAPNVRKDRRKLTPSEQEGRKSRRSSSHNLSDSSFRPASPTVSVSSNSPTPSEVTRTASPQLSDSSSSPAPGSPVLTSPSSTTSGSRTPPLALVTNGAESAAVPQQQHNLGRSFMSQYIAHMGISRRRLKKERSITEENSSIFSRASFSETDSAPETPTQTTADQPSRTVGKRVFKQQQADSVCPESVNRDLPVLRHYADTFLRSLAVSEWEKTKKSSALQEKPSESEAPTETEEQISLSTTTTESISGQESQGENVSRHTLEQPEDTTTAHNEAEGGLQHQGSTAEQHSTLSDDQRFVMDMLYSKSNTSSGALESPSLESALEGHGIRSMAVRLSRLQSSSSQPTEDPSRRAELESLGGTADAARARLAEEQKLKKLRPQYSIEAETHSQSLEKTLMTPLSRGSQDAWDKLQPSSRPLRIKDLDFSDLMEEEDIDVLDIDTFDTGLSNVIPPPPPPVPGLGSAPPPPPPPPPPGPAGLFSPPPPPPPPPPGFAGLASPPPPPPPPGGLSIPPPPGLFTTSPSQGLDPAFVKKRKTVKLFWKELKQSDSPRKCKFGRGTVWASLDKVDVDTAKLEHLFESKGKDLPVAKKGAEVKKAAISVLDPKRSNAINIGMTVLPAIHVIKSAILTFDEFAISKEGIEKILTMTPTEEEKQKIQEAQLANPDVPLGTAEQFLLTLSSISGLTARLQLWAFKLNYETLEKEIAEPLFDLKQGMEQLAKNKTFKRILATLLAIGNFLNSSRAKGFELGYLEKVTEVKDTVHRQSLLHHTCNFVVENYPDTTDLYSEIPAITRSAKVEFEQLSENLIQLERKCKTSWDNLKVVAKHETKPNLKNKMTEFLKDCTERIIILKVVHRRIINRFHSFLLYLGHPSYSVRDTKVTHFCKIISEFALEYRTTRERVLTQKRKRAVHRERTKTRGKLITETEKFSGAVTELSLDSSPSPVFSAVESEPAQEEHENMKNLLIANNDNKLLRRSRAVRKILTTAGDTSPVSPSLQWSDEEEPCDSDSAHTSPVESQSARDEDDEGVGRLSTHMSVAKEDSASSQDDATDEIMDRLVKSVTQNPTERASSPKTRKRSRLNRKSLRRTLKSGLSVEVVQALGLGSSNGKV", "length": 1441 }, "evidence": [ { "id": "FB:FBgn0266084", "url": "https://alliancegenome.org/gene/FB:FBgn0266084#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E1JI78-1", "protein_name": "Formin homology 2 domain containing, isoform I", "gene_name": "Fhos", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSYRSYTPWKTSLGSSYKPGSSTYGTSGDSTSRYTSLATPSSYRPSFSGGTYRLKRDPPPPVTTTPVSSYVSRYAKTEPKDAAPSERSSPVKRYTGNTTSSLGKYGRSRDPSPVALEHTNRNKSRDPSPVIDSARSKLGSTYRGGNTPTTSSSSSSATRNAYSSRYGAGSRISGNGSALSYLTTSDFHARTASRAKASREREREKEKEKEKEQEIEEKPSETSNGIDKSPAKQQVEKPENDEEPNETFITISVVTRATSPTLPGSTTVQRTRRIDPAKTIEKTIQRSSKRRETTDQEIQSDRLDDSTRYLRYSAGSSISSTYSPHRDRISSLRYSASPLNSSGSAKSSSVGEGKQIQPIPETVSPARTNGSVSSAKSSEALSPPRTNGNVSSGKSSEALSLPRSNGCSSKSTEAVSPPRTNGSLSSSKSTKSKLSPPKAIRLNSRQSSVENLVNKPPAPPSKADSPTKTCSSSSGSSAVKWPNKDFRKSSLNVGPTDRPRKSRTPSSGGESEDLPNGSSLERSPSAGSDGSLASGSSSKKSSKLSNGKVPGSLKPKSHKSCSETTTGNSSSATASASDSEQRVKSVKKQAKKKTTTKEGGAGKVANANKTNSTTESPPAVVDVVPATQTRLKKLSAVSNFFASRQQDANNEPIFLESSESSGEPEAHSLPVISAISGTSKISKISGISLTTDLRTNEPRTTPSSEAKQSPQTNSPSSSTRCPRETTTETGTRLPSSTTSTTQESSLTTTASLTTSEQDDPSWWQDTSLQINTASALDQNNRGEMPSYRLRHIDSGEEQAWWLRQDENGDDDDTLAEETLNTLDDDLQEPSKSTWWSQDDQDSSSQVKLMPRSRITPEKDAWWLQDEDEAAKSPIENGDLNNNNNSEPHVEVTLRLPSNGSQRSSKSSASKNGSNPKSGGANPWWLSGPARKMFNVQRVESGERAWWQEEAEEPPQEEKESEPPPVKPPTPPPRIIKHWESGERAWWLQDETESNQLPVQASSDDEEQPVLVVINQQESRDEVDLRLAPPTLESQELSNSFNFDAHSERPPPLGQCASPVRCPSPYDNIPRSQLQEPPPPPTTTLTSLQPRFSPQTRRAGEKLFISRHQNIDELLGGACRPLSPLFYGNSNPAESELTPLAGKNMFLLEEVTPDQVRIHDSTAQLPVIQRMQRDVEWLDNGSNFYEPPEQRQHQPPRRIDDAAIQVYKDGDYGAYLDLESSLAEQAEEIEGVNVSRKNSLVVRTQLNVRVQAIIEKLLSAQGSDLRRALFSLKQVFQEDKDLVHAFVALGGLNCLVRVGNCADQNYQNYILRALGQVMLYVDGMNGVMKHEPTMQWLYSLIASNYRSVVKTALKLLLVFVEYAESNCYVLVSAIHAVDASQGTLPWSNIMRLLKDYDNADAELVIYATSLINKTLAGLNDQDSFYDESDLLEQQGMETVIQRYMSKPGTDLDLLDQLQLYEAVLKFEDGESDGQRLPQNSMRKTQRYRPGANTTERRKSRRHSTDNSPASLTKVLPTTVLRMTPTQATVDEDSSGSTNSTEFSGGLFNEKKPRDGAGVTPGLRRRRERAERHKSFLKEQQEAAANGIFAALEQREGLGQIVTAIPATIQTGDSPPQSLQHEVPPCNNISGITNISNNNVSNLSCNDTPNNSLLVMSPSKQLLTGSHSISIINNSFDKASNNNQSEFLTKKNLFRERNSTVINGIMKNIQQTDSAYKKYENEANRLNNYYSQSPKHQIHQPIQPTPEVLLSPKKTLNASGFDFTPAPLSSTPVKCDVPPEPEPLSPVKKPAAAPPPPPPPPPPPPPPPGWWHAPIYNSPQARTLTSTNPELLPHPVDPSDMESEDQQLLLQLKRDHTVKDLTQKLSNLPMSPTQDSANRALVGDMSGLISKAKEGLAKSKSKGEISRSSSVDQDVKKSEPKKSENELHWEELVRNMTRPLNLCDLDFTDLRDDDEKDVLAPRSLGAGIPPPPPPLGGAIAPPPMMPPSLAPPPMYGYGGSLTNSVNSLNGSINGELVNGNNTIKKNKKTVKLFWKEVREDMIPQVVGKTIWDELPDANVDTQKLEHLFESRAKDLMTKKQQELNKSKEIIVLDHKRSNAINIAITKLPPPRAIKTAILKMDATVVTREGIDKLLNMLPTDEERGKIQEAQLSNPELPLGSAEQFLLTLASISELEARLKLWAFRLDFDNSEKEIAEPLMDLKQGIEILRQNRTFRSILSTLLSVGIFLNGAPVKGFQIEYLAKVPEVKDTVHKHSLLHHLCHMVMESSSDTSDLYSEIGPITRASKADFTDLAHNLNQLEAECKACWDRLKLIAKHDCPPPLKQKLVDFLADCAERIIILQIVHRRVMNRYRKFLLWLGMPQHSVAESRPNEFCRTLSEFALEYRTTRERVQQQLEKKANHRERNKTRGKLIIDMAKFKTKDDVADDELKKLLDTSSADQADGTLTWRRRRAEQLRSPITRQSEEQFTDGDDEILESLVKTATKAPGTRTTPRERKRTRHADRKSLRRTLKNGLTEEEKQHVAALIQTY", "length": 2528 }, "evidence": [ { "id": "RGD:2322319", "url": "https://alliancegenome.org/gene/RGD:2322319#orthology", "database": "AGR" }, { "id": "HGNC:26178", "url": "https://alliancegenome.org/gene/HGNC:26178#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081028-61", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081028-61#orthology", "database": "AGR" }, { "id": "MGI:1925847", "url": "https://alliancegenome.org/gene/MGI:1925847#orthology", "database": "AGR" }, { "id": "FB:FBgn0266084", "url": "https://alliancegenome.org/gene/FB:FBgn0266084#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F1LRX2-1", "protein_name": "Formin homology 2 domain containing 3", "gene_name": "Fhod3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MATLACRVQFLDDTDPFNSTNFPEPSRPPLFTFREDLALGTQLAGVHRLLRAPHKLDDCTLQLSHNGAYLDLEATLAEQRDELEGFQDDTGRGKKNSIILRTQLSVRVHACIEKLYNSTGRDLRRALFSLKQIFQDDKDLVHEFVIAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGVINHSETIQWLYTLVGSKFRLVVKTALKLLLVFVEYSESNAPLLIQAVSAVDTKRGVKPWSNIMEILEEKDGVDTELLVYAMTLVNKTLAGLPDQDTFYDVVDCLEELGIAAVSQRHLNKKGTDLDLLEQFNIYEVALRHEDGDETAEPPPSGHRDRRRASMCSGGTVGEQQGLDRRRSRRHSIQNIKSPLSAPTSPCSQTVPAFKPSQVRDLCEKDEEEEEEEQPITEPNSEEEREDDAQCQGKDSKASSASKQSPPEKDATPESSTLRTTSSPTSQGRWLPANPAAQSPVLAGTSGPEASRPAARLPPPSPVLAPRPSTAPKVSPTIDKLPYVPHSPFHLFSYDFEDSPLLTKDKGGDSQTENRYSNFSSSSFQSSRPSPGPSVSPSSASSFSSPQDTRSSPSGLLTSSFRQHQESLAAERERRRQEREERLQRIEREERNKFNREYLDKREEQRQARGERYKYLEHLAAEAHEKEQRSRSASRGRADLSLDLSLPAAPASPSPSSPSPDSADSQEALTVPSTPPTLQYPQVSGKDREPELEAEAGQGADEASRDIASAHREAGSQEEPALELEPEERASLSEKERQNEEVNERDNCSASSISSSSSTLEREEKEDKLSGDRPTGLWSASLQDVGVNGQCGDILTSKRFMLDMLYAHNRKSTEDEEKGDGEPGRSAQEVEAVASLATRISTLQANSQAPEESIKRVDIGCLDNRGSVKAFAEKFNSGEVGRGSVSPDAESQDKVPDTPPAQLKTESDYIWDQLMANPRELRIQDMDFTDLGEEDDIDVLDVDLGHREAPGPPPPPPPTFLGLPPPPPPPLLDSVPPPPVPGNLLASPVFNTPQGLGWSQVPKGQPAFTKKKKTIRLFWNEVRPFEWPSKNNRRCREFLWSKLEPIKVDTSRLEHLFESKSKELSVTKKTAADGKRQEIIVLDSKRSNAINIGLTVLPPPRTIKIAILNFDEYALNKEGIEKILTMIPTEEEKQKIQEAQLANPEVPLGSAEQFLLTLSSISELSARLHLWAFKMDYETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGTNAKAFELSYLEKVPEVKDTVHKQSLLHHVCTMVVENFPDSSDLYSEIGAITRSAKVDFDQLQDNLCQMERRCKASWDHLKAIAKHEMKPVLKQRMSELLKDCAERIIILKIVHRRIINRFHSFLLFMGHPPYAIREVNINKFCRIISEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITDTDDEDDTESGKFSGSSPAAPSQPQGLSYAEDAAEHENMKAVLKTSSPALEDATPMLGVRTRSRASRGSTSSWTMGTEESPSVPDDAADEIMDRIVKSATQVPSQRVVPRERKRSRANRKSLRRTLKSGLTPEEARALGLVGTSELQL", "length": 1586 }, "evidence": [ { "id": "RGD:2322319", "url": "https://alliancegenome.org/gene/RGD:2322319#orthology", "database": "AGR" }, { "id": "HGNC:26178", "url": "https://alliancegenome.org/gene/HGNC:26178#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081028-61", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081028-61#orthology", "database": "AGR" }, { "id": "MGI:1925847", "url": "https://alliancegenome.org/gene/MGI:1925847#orthology", "database": "AGR" }, { "id": "FB:FBgn0266084", "url": "https://alliancegenome.org/gene/FB:FBgn0266084#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2V2M9-1", "protein_name": "FH1/FH2 domain-containing protein 3", "gene_name": "FHOD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATLACRVQFLDDTDPFNSTNFPEPSRPPLFTFREDLALGTQLAGVHRLLQAPHKLDDCTLQLSHNGAYLDLEATLAEQRDELEGFQDDAGRGKKHSIILRTQLSVRVHACIEKLYNSSGRDLRRALFSLKQIFQDDKDLVHEFVVAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGVINRNETIQWLYTLIGSKFRLVVKTALKLLLVFVEYSESNAPLLIQAVTAVDTKRGVKPWSNIMEILEEKDGVDTELLVYAMTLVNKTLSGLPDQDTFYDVVDCLEELGIAAVSQRHLNKKGTDLDLVEQLNIYEVALRHEDGDETTEPPPSGCRDRRRASVCSSGGGEHRGLDRRRSRRHSVQSIKSTLSAPTSPCSQSAPSFKPNQVRDLREKYSNFGNNSYHSSRPSSGSSVPTTPTSSVSPPQEARLERSSPSGLLTSSFRQHQESLAAERERRRQEREERLQRIEREERNKFRYKYLEQLAAEEHEKELRSRSVSRGRADLSLDLTSPAAPACLAPLSHSPSSSDSQEALTVSASSPGTPHHPQASAGDPEPESEAEPEAEAGAGQVADEAGQDIASAHEGAETEVEQALEQEPEERASLSEKERQNEGVNERDNCSASSVSSSSSTLEREEKEDKLSRDRTTGLWPAGVQDAGVNGQCGDILTNKRFMLDMLYAHNRKSPDDEEKGDGEAGRTQQEAEAVASLATRISTLQANSQTQDESVRRVDVGCLDNRGSVKAFAEKFNSGDLGRGSISPDAEPNDKVPETAPVQPKTESDYIWDQLMANPRELRIQDMDFTDLGEEDDIDVLDVDLGHREAPGPPPPPPPTFLGLPPPPPPPLLDSIPPPPVPGNLLVPPPPVFNAPQGLGWSQVPRGQPTFTKKKKTIRLFWNEVRPFDWPCKNNRRCREFLWSKLEPIKVDTSRLEHLFESKSKELSVSKKTAADGKRQEIIVLDSKRSNAINIGLTVLPPPRTIKIAILNFDEYALNKEGIEKILTMIPTDEEKQKIQEAQLANPEIPLGSAEQFLLTLSSISELSARLHLWAFKMDYETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGTNAKAFELSYLEKVPEVKDTVHKQSLLHHVCTMVVENFPDSSDLYSEIGAITRSAKVDFDQLQDNLCQMERRCKASWDHLKAIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRIINRFHSFLLFMGHPPYAIREVNINKFCRIISEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITDSGKFSGSSPAPPSQPQGLSYAEDAAEHENMKAVLKTSSPSVEDATPALGVRTRSRASRGSTSSWTMGTDDSPNVTDDAADEIMDRIVKSATQVPSQRVVPRERKRSRANRKSLRRTLKSGLTPEEARALGLVGTSELQL", "length": 1422 }, "evidence": [ { "id": "RGD:2322319", "url": "https://alliancegenome.org/gene/RGD:2322319#orthology", "database": "AGR" }, { "id": "HGNC:26178", "url": "https://alliancegenome.org/gene/HGNC:26178#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081028-61", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081028-61#orthology", "database": "AGR" }, { "id": "MGI:1925847", "url": "https://alliancegenome.org/gene/MGI:1925847#orthology", "database": "AGR" }, { "id": "FB:FBgn0266084", "url": "https://alliancegenome.org/gene/FB:FBgn0266084#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P9Q4-1", "protein_name": "FH1/FH2 domain-containing protein 1", "gene_name": "Fhod1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGEEERGDGDPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLSAQIPALHRLLGAPLKLEDCALQVSPSGYYLDPELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRVNAILEKLYGSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSETVQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLFIQAVNAVASATGTLPWANLVSILEEKNGADAELLVYTVTLINKTLAALPDQDSFYDVTDALEQQGMEALVQRFLGTAGTDVDLRTQLTLYESALRLEDGDMEEAAAAAAAGGRRERRKPSSEEGKRSRRSLEGGGCPVRAPEPGSTGSASPVGSTPSTGSAPPTNPAFSSTGPASGLLRTSVNLFPTISVGPSVDSSCERSVYKARFLENVAAAETEKQAALAQGRAETLAGATVDDTDGSSGTRELWDSPEPASAPRTPQSPVSRILLRTQRSLEPEPKKPVSPPSPKAEPIQEPPTCVPKLCIGDLDFSDLGEDEDQDTLNVESVEAGKASPFLSSLSPSLSGGPPPPPPPPPPITGSCPPPPPPPLPPPATGSCPPPPPPPPPPIIGSCPPPPPLAAPFTHSALDGPRHPTKRKTVKLFWRELKLTGGPGCSRSRFGPCPTLWASLEPVSVDTARLEHLFESRAKDVLPTKKAGEGRRTMTVVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDVPLGPAENFLMTLASIGGLAARLQLWAFKLDYESMEREIAEPLFDLKVGMEQLVHNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSEVKDTVRRQSLLYHLCSLVLQTRPDSSDLYSEIPALTRCAKVDFEQLTENLGQLECRSQAAEDSLRSLAKHELSPALRARLTHFLAQCTRRVAMLRVVHRRVCNRFHAFLLYLGYTPQAARDVRIMQFCHTLREFALEYRTCRERVLQQQQKRATYRERNKTRGRMITETEKFSGVAGEAPNNLSVPVAVGSGPGQGDTDNHASMKSLLTSRPEDATHSRRSRGMVQSSSPVSHTAVGPSAASPEETAASGLPTDTSDEIMDLLVQSVTKSGPRALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKAPGLEV", "length": 1197 }, "evidence": [ { "id": "FB:FBgn0266084", "url": "https://alliancegenome.org/gene/FB:FBgn0266084#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q76LL6-1", "protein_name": "FH1/FH2 domain-containing protein 3", "gene_name": "Fhod3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATLACRVQFLDDTDPFNSTNFPEPSRPPLFTFREDLALGTQLAGVHRLLRAPHKLDDCTLQLSHNGAYLDLEATLAEQRDELEGFQDDTGRGKKNSIILRTQLSVRVHACIEKLYNSSGRDLRRALFSLKQIFQDDKDLVHEFVIAEGLTCLIKVGAEADQNYQNYILRALGQIMLYVDGMNGVINHSETIQWLYTLVGSKFRLVVKTALKLLLVFVEYSESNAPLLIQAVSAVDTKRGVKPWSNIMEILEEKDGVDTELLVYAMTLVNKTLAGLPDQDTFYDVVDCLEELGIAAVSQRHLNKKGTDLDLLEQFNIYEVALRHEDGDETAEPPPSGHRDRRRASMCSGGTVGEQQGLDRRRSRRHSIQNIKSPLSAPTSPCSPSVPAFKPSQVRDLCEKDEEEEEEEEQPITEPNSEEEREDDAQCQGKDSKASSASGQSSPGKDAAPESSALHTTSSPTSQGRWLSASTAARSPVLGGTSGPEASRPAARLLPPSPGLATRPSTAPKVSPTIDKLPYVPHSPFHLFSYDFEDSPLLTKDKGGDSQTENRYSNFSSNSFQSSRPSPGPSGSPSYASSFSSPQDTRSSPSGLLTSSFRQHQESLAAERERRRQEREERLQRIEREERNKFNREYLDKREEQRQARGERYKYLEQLAAETQEKEPRSQSVSRGRADLSLDLSLPAAPAPPSPSSQSPSADSQEALPVPSSPPTLQCPQVSGKDHEPELEAEAGQGADEASQDIASAHRGAESQEEPVLELEPEERASLSEKERQNEEVNERDNCSASSISSSSSTLEREEKEDKLSEDRATGLWSTSLQDVGVNGQCGDILTSKRFMLDMLYAHNRKSTEDEEKDDGEPGRSAQEVEAVASLATRISTLQANSQAPEESIKRVDIGCLDNRGSVKAFAEKFNSGEVGRGAISPDVESQDKVPDTPPAQLKTESDYIWDQLMANPRELRIQDMDFTDLGEEDDIDVLDVDLGHREAPGPPPPPPPTFLGLPPPPPPPLLDSVPPPPVPGNLLASPVFNTPQGLGWSQVPRGQPAFTKKKKTIRLFWNEVRPFEWPSKNNRRCREFLWSKLEPIKVDTSRLEHLFESKSKELSVTKKTAADGKRQEIIVLDSKRSNAINIGLTVLPPPRTIKIAILNFDEYALNKEGIEKILTMIPTEEEKQKIQEAQLANPEVPLGSAEQFLLTLSSISELSARLHLWAFKMDYETTEKEVAEPLLDLKEGIDQLENNKTLGFILSTLLAIGNFLNGTNAKAFELSYLEKVPEVKDTVHKQSLLHHVCTMVVENFPDSSDLYSEIGAITRSAKVDFDQLQDNLCQMERRCKASWDHLKAIAKHEMKPVLKQRMSEFLKDCAERIIILKIVHRRIINRFHSFLLFMGHPPYAIREVNINKFCRIISEFALEYRTTRERVLQQKQKRANHRERNKTRGKMITDSGKFSGSSPAAPSQPQGLSYAEDAAEHENMKAVLKTSSPALEDATPVLGVRTRSRASRGSTSSWTMGTEESPSVTDDAADEIMDRIVKSATQVPSQRVVPRERKRSRANRKSLRRTLKSGLTPEEARALGLVGTSELQL", "length": 1578 }, "evidence": [ { "id": "RGD:2322319", "url": "https://alliancegenome.org/gene/RGD:2322319#orthology", "database": "AGR" }, { "id": "HGNC:26178", "url": "https://alliancegenome.org/gene/HGNC:26178#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081028-61", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081028-61#orthology", "database": "AGR" }, { "id": "MGI:1925847", "url": "https://alliancegenome.org/gene/MGI:1925847#orthology", "database": "AGR" }, { "id": "FB:FBgn0266084", "url": "https://alliancegenome.org/gene/FB:FBgn0266084#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y613-1", "protein_name": "FH1/FH2 domain-containing protein 1", "gene_name": "FHOD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGEDRGDGEPVSVVTVRVQYLEDTDPFACANFPEPRRAPTCSLDGALPLGAQIPAVHRLLGAPLKLEDCALQVSPSGYYLDTELSLEEQREMLEGFYEEISKGRKPTLILRTQLSVRVNAILEKLYSSSGPELRRSLFSLKQIFQEDKDLVPEFVHSEGLSCLIRVGAAADHNYQSYILRALGQLMLFVDGMLGVVAHSDTIQWLYTLCASLSRLVVKTALKLLLVFVEYSENNAPLFIRAVNSVASTTGAPPWANLVSILEEKNGADPELLVYTVTLINKTLAALPDQDSFYDVTDALEQQGMEALVQRHLGTAGTDVDLRTQLVLYENALKLEDGDIEEAPGAGGRRERRKPSSEEGKRSRRSLEGGGCPARAPEPGPTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIYKARFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETAPAARTPQSPAPCVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAPRLSIGDLDFSDLGEDEDQDMLNVESVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPLPHSVPDSSALPTKRKTVKLFWRELKLAGGHGVSASRFGPCATLWASLDPVSVDTARLEHLFESRAKEVLPSKKAGEGRRTMTTVLDPKRSNAINIGLTTLPPVHVIKAALLNFDEFAVSKDGIEKLLTMMPTEEERQKIEEAQLANPDIPLGPAENFLMTLASIGGLAARLQLWAFKLDYDSMEREIAEPLFDLKVGMEQLVQNATFRCILATLLAVGNFLNGSQSSGFELSYLEKVSEVKDTVRRQSLLHHLCSLVLQTRPESSDLYSEIPALTRCAKVDFEQLTENLGQLERRSRAAEESLRSLAKHELAPALRARLTHFLDQCARRVAMLRIVHRRVCNRFHAFLLYLGYTPQAAREVRIMQFCHTLREFALEYRTCRERVLQQQQKQATYRERNKTRGRMITETEKFSGVAGEAPSNPSVPVAVSSGPGRGDADSHASMKSLLTSRPEDTTHNRRSRGMVQSSSPIMPTVGPSTASPEEPPGSSLPSDTSDEIMDLLVQSVTKSSPRALAARERKRSRGNRKSLRRTLKSGLGDDLVQALGLSKGPGLEV", "length": 1164 }, "evidence": [ { "id": "FB:FBgn0266084", "url": "https://alliancegenome.org/gene/FB:FBgn0266084#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03" } ], "pmid": "" }, { "name": "actin filament binding", "id": "GO:0051015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051015", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "actin filament organization", "id": "GO:0007015", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007015", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03" } ], "pmid": "" }, { "name": "positive regulation of stress fiber assembly", "id": "GO:0051496", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051496", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03" } ], "pmid": "" }, { "name": "cardiac myofibril assembly", "id": "GO:0055003", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0055003", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03" } ], "pmid": "" }, { "name": "sarcomere organization", "id": "GO:0045214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045214", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1340, "end_pos": 1342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1358, "end_pos": 1360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1534, "end_pos": 1536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1626, "end_pos": 1628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1629, "end_pos": 1631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 462, "end_pos": 464, "annotation": "n_glycosylation_sequon" }, { "start_pos": 579, "end_pos": 581, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 836, "end_pos": 838, "annotation": "n_glycosylation_sequon" }, { "start_pos": 874, "end_pos": 876, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PK03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03" }, { "id": "PS51231", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51231" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DAD", "eco_id": "ECO_0000259", "start_pos": 1629, "end_pos": 1661, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PK03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03" }, { "id": "PS51444", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51444" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FH2", "eco_id": "ECO_0000259", "start_pos": 1143, "end_pos": 1539, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PK03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK03" }, { "id": "PS51232", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51232" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GBD/FH3", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 424, "start_aa": "Asn", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 349 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 1340, "end_pos": 1342 }, { "start_pos": 1358, "end_pos": 1360 }, { "start_pos": 1534, "end_pos": 1536 }, { "start_pos": 1626, "end_pos": 1628 }, { "start_pos": 1629, "end_pos": 1631 }, { "start_pos": 189, "end_pos": 191 }, { "start_pos": 18, "end_pos": 20 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 462, "end_pos": 464 }, { "start_pos": 579, "end_pos": 581 }, { "start_pos": 66, "end_pos": 68 }, { "start_pos": 836, "end_pos": 838 }, { "start_pos": 874, "end_pos": 876 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PRQ8-1", "uniprot_ac": "A0A8M9PRQ8", "uniprot_id": "A0A8M9PRQ8_DANRE", "mass": { "chemical_mass": 73264.0, "monoisotopic_mass": 73264.0 }, "refseq": { "ac": "XP_001340716", "name": "zinc finger BED domain-containing protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001340716" }, "gene_names": [ { "name": "si:dkeyp-106c3.2", "type": "recommended", "evidence": [ { "id": "A0A8M9PRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8" } ] }, { "name": "zbed4l1", "type": "recommended", "evidence": [ { "id": "A0A8M9PRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8" } ] }, { "name": "si:dkey-13n23.3", "type": "synonym", "evidence": [ { "id": "A0A8M9PRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8" } ] }, { "name": "zbed4l1", "type": "synonym", "evidence": [ { "id": "XP_001340716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001340716" }, { "id": "A0A8M9PRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8" } ] } ], "protein_names": [ { "name": "Zinc finger BED domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "A0A8M9PRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8/entry#names_and_taxonomy" } ] }, { "name": "zinc finger BED domain-containing protein 4", "type": "synonym", "evidence": [ { "id": "XP_001340716", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001340716" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001340716.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001340716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001340716" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zbed4l1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-527", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-527", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ZFIN:ZDB-GENE-120214-42", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120214-42", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000070465", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000070465", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100000534", "url": "https://www.ncbi.nlm.nih.gov/gene/100000534", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "100001550", "url": "https://www.ncbi.nlm.nih.gov/gene/100001550", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003656", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003656", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100000534", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000534", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "dre:100001550", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001550", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DYCKESD", "url": "https://omabrowser.org/oma/group/DYCKESD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "MWMESES", "url": "https://omabrowser.org/oma/group/MWMESES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PRQ8", "url": "https://www.orthodb.org/?gene=A0A8M9PRQ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A5WUN3", "url": "https://www.orthodb.org/?gene=A5WUN3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46481", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46481", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46481:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46481:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02892", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02892", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27039", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27039", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001340716", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001340716", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PRQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PRQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WUN3", "url": "https://www.uniprot.org/uniprotkb/A5WUN3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WUN3-1", "url": "https://www.uniprot.org/uniprotkb/A5WUN3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-527", "url": "https://zfin.org/ZDB-GENE-070705-527", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] }, { "id": "ZDB-GENE-120214-42", "url": "https://zfin.org/ZDB-GENE-120214-42", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNRQTEMSELGLGRKRRIDIWSNFTYDNKDNKSVCKPCGVKIAGKNTTNLKRHLQTAHPEIHTKIQKMSDDHGPGGNKASDATSTTQQQAISDFLRSSKYKTESKEQQTKEQAIARWIGRTGLPLTTVEDEDFVLMMGMIDGRLTVPKKTKISNLIETQYEHERQKFRESLAAARKVSIGLDLWTKKGLTASFLAISACYFCVEKSKPAHILLALQQVGHPHTAQAIKACVDKCMQEWTIPKEKILTVITDNGSNMVAAFKNTTAEETSSEDDSPGSTIESDSEIDDQRYRHVDMELDRTPCVVHTIQLVVHMLQKETTVKRVLDKARSVVKLFRKSSVATQKLLDQCGVIVVNDCPTRWSSTFNMITRLLKVKDAVCQISNDMGWDSLLTSEWQKLSSLHDLLLPFAEHTKTLQSDTTSMSLVVPALFDLLTHLTDFAVNTRYRDLATLADKMRSNLNQRFACILDTTDEKFSPLAAAACFVNPTVCEIIVNVDVANGNIQELLKQAEDYVVKCTKQEGQSENDEEEVIEEPEAAPSSKQPVFRFLSKCRTTRPKQKTSTSNIRQQIIKYKEELSHPITEDTGTDFWLGKSDSVYHSLKPFALDLLAMPASQAFAERVFSITGDLTRGRRNRGRVTLERSAFLKMNRNK", "length": 650, "header": "tr|A0A8M9PRQ8-1|A0A8M9PRQ8_DANRE Isoform 1 of Zinc finger BED domain-containing protein 4 OS=Danio rerio OX=7955 GN=zbed4l1 PE=4 SV=1 CANONICAL=A0A8M9PRQ8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PRQ8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8/entry#A0A8M9PRQ8-1", "sequence": { "sequence": "MNRQTEMSELGLGRKRRIDIWSNFTYDNKDNKSVCKPCGVKIAGKNTTNLKRHLQTAHPEIHTKIQKMSDDHGPGGNKASDATSTTQQQAISDFLRSSKYKTESKEQQTKEQAIARWIGRTGLPLTTVEDEDFVLMMGMIDGRLTVPKKTKISNLIETQYEHERQKFRESLAAARKVSIGLDLWTKKGLTASFLAISACYFCVEKSKPAHILLALQQVGHPHTAQAIKACVDKCMQEWTIPKEKILTVITDNGSNMVAAFKNTTAEETSSEDDSPGSTIESDSEIDDQRYRHVDMELDRTPCVVHTIQLVVHMLQKETTVKRVLDKARSVVKLFRKSSVATQKLLDQCGVIVVNDCPTRWSSTFNMITRLLKVKDAVCQISNDMGWDSLLTSEWQKLSSLHDLLLPFAEHTKTLQSDTTSMSLVVPALFDLLTHLTDFAVNTRYRDLATLADKMRSNLNQRFACILDTTDEKFSPLAAAACFVNPTVCEIIVNVDVANGNIQELLKQAEDYVVKCTKQEGQSENDEEEVIEEPEAAPSSKQPVFRFLSKCRTTRPKQKTSTSNIRQQIIKYKEELSHPITEDTGTDFWLGKSDSVYHSLKPFALDLLAMPASQAFAERVFSITGDLTRGRRNRGRVTLERSAFLKMNRNK", "length": 650, "header": "tr|A0A8M9PRQ8-1|A0A8M9PRQ8_DANRE Isoform 1 of Zinc finger BED domain-containing protein 4 OS=Danio rerio OX=7955 GN=zbed4l1 PE=4 SV=1 CANONICAL=A0A8M9PRQ8-1" }, "locus": {} }, { "isoform_ac": "A5WUN3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8/entry#A5WUN3-1", "sequence": { "sequence": "MNRQTEMSELGLGRKRRIDIWSNFTYDNKDNKSVCKPCGVKIAGKNTTNLKRHLQTAHPEIHTKIQKMSDDHGPGGNKASDATSTTQQQAISDFLRSSKYKTESKEQQTKEQAIAR", "length": 116, "header": "tr|A5WUN3-1|A0A8M9PRQ8_DANRE Computationally mapped isoform of Zinc finger BED domain-containing protein 4 OS=Danio rerio OX=7955 GN=zbed4l1 PE=4 SV=1 CANONICAL=A0A8M9PRQ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100000534", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000534", "resource": "KEGG Pathway" }, { "id": "dre:100001550", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001550", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRQ8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PRQ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ8" }, { "id": "PS50808", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50808" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BED-type", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 65, "start_aa": "Lys", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 23, "end_pos": 25 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 262, "end_pos": 264 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UR37-1", "uniprot_ac": "A0A8N7UR37", "uniprot_id": "A0A8N7UR37_DANRE", "mass": { "chemical_mass": 44173.0, "monoisotopic_mass": 44173.0 }, "refseq": { "ac": "XP_692327", "name": "zona pellucida-like domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692327" }, "gene_names": [ { "name": "si:ch211-229d2.5", "type": "recommended", "evidence": [ { "id": "A0A8N7UR37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR37" } ] }, { "name": "si:ch211-229d2.5", "type": "synonym", "evidence": [ { "id": "XP_692327", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692327" } ] } ], "protein_names": [ { "name": "Zona pellucida-like domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UR37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR37/entry#names_and_taxonomy" } ] }, { "name": "zona pellucida-like domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_692327", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692327" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_692327.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_692327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692327" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR37", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR37" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-229d2.5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR37", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-121214-200", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-200", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UR37", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UR37", "database": "AlphaFoldDB", "categories": [] }, { "id": "563874", "url": "https://www.ncbi.nlm.nih.gov/gene/563874", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:563874", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563874", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z0V7", "url": "https://www.orthodb.org/?gene=A0A8M6Z0V7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UR37", "url": "https://www.orthodb.org/?gene=A0A8N7UR37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00100", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00100", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_692327", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692327", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z0V7", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0V7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z0V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z0V7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UR37", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UR37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-121214-200", "url": "https://zfin.org/ZDB-GENE-121214-200", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKSMVDMVLLRLLILGTLVQPGYLGLTPASCGNNYRRPEITDIGVSCGTNSINLAIQACPVVYSGYNETLLILNQIANDPLCQGTLDANVTPPVVRFVFPIRQLDSCGSFFRTTSAAGTGAFSDFSNIQTVYISGVVRSFDPTMGTVTYNAELKYIYSCAYPLEYLINNTQVDVSASSIAVRDNNGSFISTLSMQLYKDINYTTPLVFPNGGIELRTRIFVQVIAVNLTSQYYVLLDRCYASISPVPSNSTYFNLFVPCNQDPMTSMLENGESQRARFSFPAFRFIEQQNQTVSTYYLHCITRLCETTTCPTFKQCRKRKRREVQTTTIKDGVSDATFITSGPITTRADTPLTTKDEAASSAQKSSGNAASVGLGVSLAVLIAVGTVAGLVAVPFYRKLKMQR", "length": 403, "header": "tr|A0A8N7UR37-1|A0A8N7UR37_DANRE Isoform 1 of Zona pellucida-like domain-containing protein 1 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-229d2.5 PE=4 SV=1 CANONICAL=A0A8N7UR37-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z0V7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR37/entry#A0A8M6Z0V7-1", "sequence": { "sequence": "MKSMVDMVLLRLLILGTLVQPGYLGLTPASCGNNYRRPEITDIGVSCGTNSINLAIQACPVVYSGYNETLLILNQIANDPLCQGTLDANVTPPVVRFVFPIRQLDSCGSFFRTTSAAGTGAFSDFSNIQTVYISGVVRSFDPTMGTVTYNAELKYIYSCAYPLEYLINNTQVDVSASSIAVRDNNGSFISTLSMQLYKDINYTTPLVFPNGGIELRTRIFVQVIAVNLTSQYYVLLDRCYASISPVPSNSTYFNLFVPCNQDPMTSMLENGESQRARFSFPAFRFIEQQNQTVSTYYLHCITRLCETTTCPTFKQCRKRKRREVQTTTIKDGVSDATFITSGPITTRADTPLTTKDEASSAQKSSGNAASVGLGVSLAVLIAVGTVAGLVAVPFYRKLKMQR", "length": 402, "header": "tr|A0A8M6Z0V7-1|A0A8N7UR37_DANRE Computationally mapped isoform of Zona pellucida-like domain-containing protein 1 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-229d2.5 PE=4 SV=1 CANONICAL=A0A8N7UR37-1" }, "locus": {} }, { "isoform_ac": "A0A8N7UR37-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR37/entry#A0A8N7UR37-1", "sequence": { "sequence": "MKSMVDMVLLRLLILGTLVQPGYLGLTPASCGNNYRRPEITDIGVSCGTNSINLAIQACPVVYSGYNETLLILNQIANDPLCQGTLDANVTPPVVRFVFPIRQLDSCGSFFRTTSAAGTGAFSDFSNIQTVYISGVVRSFDPTMGTVTYNAELKYIYSCAYPLEYLINNTQVDVSASSIAVRDNNGSFISTLSMQLYKDINYTTPLVFPNGGIELRTRIFVQVIAVNLTSQYYVLLDRCYASISPVPSNSTYFNLFVPCNQDPMTSMLENGESQRARFSFPAFRFIEQQNQTVSTYYLHCITRLCETTTCPTFKQCRKRKRREVQTTTIKDGVSDATFITSGPITTRADTPLTTKDEAASSAQKSSGNAASVGLGVSLAVLIAVGTVAGLVAVPFYRKLKMQR", "length": 403, "header": "tr|A0A8N7UR37-1|A0A8N7UR37_DANRE Isoform 1 of Zona pellucida-like domain-containing protein 1 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-229d2.5 PE=4 SV=1 CANONICAL=A0A8N7UR37-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:563874", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563874", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": 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"database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H7W1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H7W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H7W1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H7W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H7W3", "url": "https://www.uniprot.org/uniprotkb/A0AC58H7W3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H7W3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H7W3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H7X2", "url": "https://www.uniprot.org/uniprotkb/A0AC58H7X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H7X2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H7X2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070308-3", "url": "https://zfin.org/ZDB-GENE-070308-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPAQEQNVHILSLMPTLDQISGFSQQSHLQPPSRELERHVASLSIHIHPRPQISGPRTQAMSLRPPTPPKRMDRQDRGSHQCRPLPSAAPPVPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1822, "header": "tr|A0A8M9PN75-1|A0A8M9PN75_DANRE Isoform 1 of Sorbin and SH3 domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z492-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0A8M6Z492-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPAQEQNVHILSLMPTLDQISGFSQQSHLQPPSRELERHVASLSIHIHPRPQISGPRTQAMSLRPPTPPKRMDRQDRGSHQCRPLPSAAPPVPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1790, "header": "tr|A0A8M6Z492-1|A0A8M9PN75_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PBP1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0A8M9PBP1-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1633, "header": "tr|A0A8M9PBP1-1|A0A8M9PN75_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PN75-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0A8M9PN75-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPAQEQNVHILSLMPTLDQISGFSQQSHLQPPSRELERHVASLSIHIHPRPQISGPRTQAMSLRPPTPPKRMDRQDRGSHQCRPLPSAAPPVPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1822, "header": "tr|A0A8M9PN75-1|A0A8M9PN75_DANRE Isoform 1 of Sorbin and SH3 domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q586-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0A8M9Q586-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1732, "header": "tr|A0A8M9Q586-1|A0A8M9PN75_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7R5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7R5-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPAQEQNVHILSLMPTLDQISGFSQQSHLQPPSRELERHVASLSIHIHPRPQISGPRTQAMSLRPPTPPKRMDRQDRGSHQCRPLPSAAPPVPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1784, "header": "tr|A0AC58H7R5-1|A0AC58H7R5_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X3 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7S0-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPAQEQNVHILSLMPTLDQISGFSQQSHLQPPSRELERHVASLSIHIHPRPQISGPRTQAMSLRPPTPPKRMDRQDRGSHQCRPLPSAAPPVPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERATSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1775, "header": "tr|A0AC58H7S0-1|A0AC58H7S0_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X4 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7S2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7S2-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPAQEQNVHILSLMPTLDQISGFSQQSHLQPPSRELERHVASLSIHIHPRPQISGPRTQAMSLRPPTPPKRMDRQDRGSHQCRPLPSAAPPVPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1540, "header": "tr|A0AC58H7S2-1|A0AC58H7S2_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X13 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7S4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7S4-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPAQEQNVHILSLMPTLDQISGFSQQSHLQPPSRELERHVASLSIHIHPRPQISGPRTQAMSLRPPTPPKRMDRQDRGSHQCRPLPSAAPPVPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERATSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1743, "header": "tr|A0AC58H7S4-1|A0AC58H7S4_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X5 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7S5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7S5-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERATSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1554, "header": "tr|A0AC58H7S5-1|A0AC58H7S5_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X12 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7S8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7S8-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1700, "header": "tr|A0AC58H7S8-1|A0AC58H7S8_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X7 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7S9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7S9-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERATSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1685, "header": "tr|A0AC58H7S9-1|A0AC58H7S9_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X8 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7T0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7T0-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1601, "header": "tr|A0AC58H7T0-1|A0AC58H7T0_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X10 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7T2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7T2-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPAQEQNVHILSLMPTLDQISGFSQQSHLQPPSRELERHVASLSIHIHPRPQISGPRTQAMSLRPPTPPKRMDRQDRGSHQCRPLPSAAPPVPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1309, "header": "tr|A0AC58H7T2-1|A0AC58H7T2_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 1 isoform X14 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7T4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7T4-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1217, "header": "tr|A0AC58H7T4-1|A0AC58H7T4_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X19 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7T5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7T5-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERATSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1202, "header": "tr|A0AC58H7T5-1|A0AC58H7T5_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X20 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7T7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7T7-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1219, "header": "tr|A0AC58H7T7-1|A0AC58H7T7_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 1 isoform X18 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7T8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7T8-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERATSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1586, "header": "tr|A0AC58H7T8-1|A0AC58H7T8_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X11 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7U0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7U0-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERATSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1170, "header": "tr|A0AC58H7U0-1|A0AC58H7U0_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X23 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7U3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7U3-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPAQEQNVHILSLMPTLDQISGFSQQSHLQPPSRELERHVASLSIHIHPRPQISGPRTQAMSLRPPTPPKRMDRQDRGSHQCRPLPSAAPPVPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1277, "header": "tr|A0AC58H7U3-1|A0AC58H7U3_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 1 isoform X15 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7U4-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1181, "header": "tr|A0AC58H7U4-1|A0AC58H7U4_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 1 isoform X22 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7U6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7U6-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1187, "header": "tr|A0AC58H7U6-1|A0AC58H7U6_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 1 isoform X21 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7U7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7U7-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1120, "header": "tr|A0AC58H7U7-1|A0AC58H7U7_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X24 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7V0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7V0-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERATSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1073, "header": "tr|A0AC58H7V0-1|A0AC58H7V0_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X26 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7V1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7V1-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 736, "header": "tr|A0AC58H7V1-1|A0AC58H7V1_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X28 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7V2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7V2-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERATSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 657, "header": "tr|A0AC58H7V2-1|A0AC58H7V2_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X31 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7V5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7V5-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPAQEQNVHILSLMPTLDQISGFSQQSHLQPPSRELERHVASLSIHIHPRPQISGPRTQAMSLRPPTPPKRMDRQDRGSHQCRPLPSAAPPVPEVPVLLKQSYPGTAQSHNRLRLSLDFIRPETFSPAGPHSPDRCSSCTQSEASTAVLEELRAFGLGPEGGSRTPSPTLSQMSVVTDSMGLHSPAASNINGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1271, "header": "tr|A0AC58H7V5-1|A0AC58H7V5_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 1 isoform X16 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7V6-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERATSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1041, "header": "tr|A0AC58H7V6-1|A0AC58H7V6_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X27 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7W0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7W0-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERATSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 689, "header": "tr|A0AC58H7W0-1|A0AC58H7W0_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X30 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7W1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7W1-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSGGQIRKCATLSLTLTPMKRIQSSPNLYSLTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKGGDVSNMHTAHSNCLSPNHSTSEPVYQNYGENEDSFMAVPAVSKGFSSLPEGWKPAQENSEDWMIAEETSPKLKSWSCDDLLSEGRGREVQTRCESTGSLLHNGELETSQYCDVQEPEDLRERTRHRSAHDAPGFLKLYKKMHHINRQELINSTVICSVKSRIRKYESEQRKDRRTGNKGCNEEVPRDMVHNRISEFESLIQKSKSMPNLGEECLIRGSSRRINSPKRSLSIESLLDEEPPARNPPEGRPQYPKINNHVPIHIHVTSDQLQNSAMQNDYSDSEHDAVVSDLSDFIQIEGSSFCSEREFDLCSFASSESFCGSGHHHHFHRQLVSSCKGRCPASYTRFTTMIKHERAKQDRRQHLRVEDSEFGLSKLAFLVSPVPFRRKNLSPLSFSRMSNSKSYVYETLDSALKDIYDHIRTEKRRSSLSENSILHRLLVELLPDIPERNSSLHALGRNSPTIQPRSYHPQPDGMSSQDIHQSEYCHLSHSASHNHIDSNNNQRNHNFKYCYQDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1249, "header": "tr|A0AC58H7W1-1|A0AC58H7W1_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X17 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7W3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7W3-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 704, "header": "tr|A0AC58H7W3-1|A0AC58H7W3_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 2 isoform X29 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} }, { "isoform_ac": "A0AC58H7X2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75/entry#A0AC58H7X2-1", "sequence": { "sequence": "MPGLCDIKTLQEGEIFNMNTDSESQSRDSDLWRPSSSTDGLRNGDVCSSSLAAKGYRSVRPIFQEKKSPTPGQMTVNGGLSVPASPRSHIQRPFSPSTYPPPPSLSPSITAMQQQARTTASSTPIYANVDPPARAPHTDRRETAGKAPHYTGIGPVDESGIPIAIRTTVDRPKDWYKTMFKQIHVVPKTEIEWSGSRTATDPVTSPATTISKQDKQAAPNAVQAHPAPKTSTYRPISKSVSDNGIYAFRLPVASPLPTSTSTQQRPIEREAPQRGRSTPDMNEWGPPDRKVDTRKYRAEPRSIFDYEPGKSSVLEQERAKSNLSPEDIDLENEPWYKFFAELEFGRPPPKKLLDYNPESAPRFPVETSLYQPSTDRSLERPSSSASDNKKRRKSEPATTQPRAHSSVGTTQTSVRPPELPRGSSTQRNPLTSPSSPATTRTKDQDTSRNYTYPDVGRQTPQSRRQTPDVKEKLPARAIYDFKAQTAKELTFKKGDTVYISRQIDNNWYEGEYHGHVGIFPISYVEKIPPSERHLPARPPPPAQSKEIGEAVARYNFNADTNVELSLRKGERVVLVRQVDKNWFEGKIPGTNKQGIFPVSYVDVIKKTSVQNTGQPPGPSIPTSFSSDRLNSRPSSTRNLHNSPSPTIRPLSSSSPSPQRAAHLQAITSEWLALTLGLSPSGTPAPTPPPFPSNFQPYYEAFDSGISPSPASSTLGRSPTLTPRVSTPALKEGHFIPISSPKSYMSPDPSPSPQPYLTSASFTPSPTSPTFDSRSGSVIEILSSHKADLPVKELQLFSDPKDRYKPGETDSPKLGSPIDLVVFEGQKSPLDILPPKDLEDDLCEELVSIIKASQSKGAFLEEEDLYHQEPDTVEKLPRLFIEEEQNEDNSFLNKTLPSNTFTPLQLAHSEGSDIEQGEVSQNASPRLSSLSSQMSLPFTSAKYSPTSPCSTPPLPGVSQSPPHLAKLFPRQDLRSPKVKPVLRRDVVVVGKPPRSPVMSRRSCGSPVRGQNFSPSNRSQRQAYACDPLQGGGEPFQALYNYMPRNEDELELKEGDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1088, "header": "tr|A0AC58H7X2-1|A0AC58H7X2_DANRE Computationally mapped isoform of Sorbin and SH3 domain-containing protein 1 isoform X25 OS=Danio rerio OX=7955 GN=sorbs2b PE=4 SV=1 CANONICAL=A0A8M9PN75-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 102, "start_aa": "Thr", "end_pos": 102, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr102", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1416, "start_aa": "Thr", "end_pos": 1416, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1416", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1420, "start_aa": "Thr", "end_pos": 1420, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1420", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1500, "start_aa": "Thr", "end_pos": 1500, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1500", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:563408", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563408", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A6M3QH40-1", "protein_name": "CAP, isoform AC", "gene_name": "CAP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPNNRNRNRNRNRNKRNRNQNQNQNPSQNQNENHQQQAEGAEDREEQQDFQTQIAVAQSSSFVDDNGNSGSVSNGPTENSEEVTNTLEKTEKKEEIFEQPATVIQKEADSDAEMGAKNSKHRKEKSDKQASNGKSEEQVRPPPTIIRRPPGSPRQAKVIVHRIVREEDTANGKAQSPEPPKAVESKEQHMEVEDSKKEKPEAQQEIETKEERENEPSPKELPESSHLSEDAQQKHVEVEENQQVYDEVDYSKDETTDNNPQQEQHDSKEPEQYVLQLEKAMEFVENAHQQHVAAVQSYQKQRDTEQNAQQQEQNEAQHLQESTKAHQQNIAVPQILVDPKKREEGLAQQLHHDVKEEPILNNAQQQNDDTAPKSPKEVTIKVQFQTEDPYSQQPPPQKPTSKVIIHQIHVETTDEEQNAKPTFEEVSSTTGSLAGTLSPPPRYLVESPKNVSSGQFSNFSRNVQIQEMELNSDFSSGEFNSLQSPLVCEVDSESEGSVVLGPERSPSDQQVPSSSRVEQHEQVRQKRAQYRNALESHFMPQLLNPRYLDSILEENEWRNSTASSGGSDQTGIRTPKLNETFPRSQLDFSRRHKRREEAPSPLKLETKLLEESTDLESCTRLQSALSPQSEDAELVYLSSSASSSVSDLMELELEQAAALAERALVDLDTDASRLIARPDDEMSSTSTTTADRSETEAETETETEREGEQSRESTPVNANPTLASSQSSLLSAATPTPTPTPTPADREQLAKDTNVSGGSTVSFGAASPLAATREEFVRNMDKVRELIEMTRREQEQGELPRSPSPPPVPPPPASVPPYSPESSSFHLASLQLKRQESNDSHCSDSTTHSQCTAINLASPPPPPTAQPPTPPLRQKPAPPPVPQPVSPPAPPTPQSEPELSVADSVANANADVDADADTDTEAIKKLRLLCTEQLASMPYGEQVLEELASVAQNISDQSQNKMPYPMPQLPHIKELQLNANESKSSSAWLGLPTQSDPKLLVCLSPGQRDLVNNQTQPDDLLDAHQKFVERRGYHELSKAQVLEQDHQQQQSEMLKTAAMMRELRKSLSPPAPPVPPPPVPVKSAETAAKATAHENAKRDDASEQKQKIAACESSSLENKPRRAADLGAQQSAEQRQSSSTTTSSHKATTETMSSDTAKFPTLDSMESELARMFPQHKGDIFEEQRKRFSNIEFPSHQPVSQTKRYSNIETSSYESKKRMENGQVVYDVSTSSHEKKEQGDPPKDQPVPPVPPPPIMSATKLNGNTFIDGDVAPKNSQPSRESGSGSGNGTYEEFRQRAKAAADAFGEQREQQNGLDQDRVFKDFDRLSQQMHAELQSTREKREKSASMYDLSGFTRPASGHPRLDELQQRRHAHMQELEREIERSAKSRQERMSSVPRQMEATPPRTHEIPIELEPRSRRAESLCNLNEPPPRPHTTVGHYNHPVVQDDWSRYANDLGYSENIARPFAREVEICYQRQNQRTPHCIRAPRLSASTNDLSSSSQYSYDTFNAYGGRRTHAPMLNQAQQQQRPHYGSCYSMIERDPNPRYISTTSRRGVSPAPPPVATPQQQQVPPPAYDRQQRRSSLPRELHEQQLKYILSKEEELKFEVERLQQERRRLMEEMQRAPVLPAPQRRESYRPAAKLPTLSEDEVFRQQMAEEWMNKVAEREERRQHKIIRISKIEDEHDHSAVDKATISDEFLDRVKERRHKLSMPADSDWESGAESQPQPAAQSQPESDVEAPPVRILEGQAEANLRQLPRHLREFAKFSTSEQLPDGAQMERHEEQERREEATDNAHSSATKKTSIVKTYKVSRLPPSVQGEFPGQFSGGNRGRLYRERSQTARLVSHNIPLELTSNHSSSPDSDFNPGCGSSPAPGSSTQSSIPSLVQSPTPAPPPPIEPLNPSSSTAGGILGTALLLGLSLLTAWNKFIYKVKHEYMSEPETGSDRPRKMAQLGRRQYDGIGPVTNDGMPIILRSEVKEPHQHEWYKRLYQTIHKQKNGDDFVIRYKCPRARPSYKSNGYVSEPEPNYDSDYSTVRYRTQNPHRVQSVSSAVNVRNLNQDEKLYGTMPNPIKSAQNSYKNQPGRIENYTTGHSSVSEKEKKEWWDEVMDIFNGNLEQSKLSPLYTEGNLSRALAKESGYTSDSNLVFRKKEVPVSSPLSPVEQKQAYKSLQAGGEPPLLGFRKPAPEKPRDLDPNAPPIPPQPPVKGLSSYDFPYSTDTVDGSDVNIHFKTPIRHEQRQNLSEEELAIRQAEHMQKLYHEERRRKYLQELQDMNSRRHTDNFTPSQKSPIALNRYDDFPTDVTLKSLVGPKTVARALFNFQGQTSKELSFRKGDTIYIRRQIDANWYEGEHNAMIGLLPASYVEIVSRDGARTPSKRPSEGQARAKYNFQAQSGIELSLNKGELVTLTRRVDGNWFEGKIANRKGIFPCSYVEVLTDIGAEDIAARTTTVITSQSTTNLRPNLDVLRTNINNEFNTLTQNGAQPPNGILKETRTLHKTDALHVDTSSEPLAYRALYKYRPQNSDELELLEGDVVHVLEKCDDGWFVGTSQRTGCFGTFPGNYVERA", "length": 2568 }, "evidence": [ { "id": "HGNC:24098", "url": "https://alliancegenome.org/gene/HGNC:24098#orthology", "database": "AGR" }, { "id": "RGD:620061", "url": "https://alliancegenome.org/gene/RGD:620061#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070308-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070308-3#orthology", "database": "AGR" }, { "id": "MGI:1924574", "url": "https://alliancegenome.org/gene/MGI:1924574#orthology", "database": "AGR" }, { "id": "FB:FBgn0033504", "url": "https://alliancegenome.org/gene/FB:FBgn0033504#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8M2B9N0-1", "protein_name": "Vinexin", "gene_name": "sorbs3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQSEKRVEVYDHLNGSRIIFSDEALPGSGSRQHFMTPDIPQDVVVISPGLPTPPSSPILNTSAPSQQKVAEVNGGGFPSHTFGSYYGPAETFGGLSNGGIQSGSDTLPKTSGTREERLIKFSGIGPVDETGMPIASRSSVNKPKDWYRSMFRQIHKKPEEPEFDWRERKLSSYSSIDSAQDGFSDTITLTQHGALTDWADLGDSGKHPEPKNIFDFEPGREAVTGDHNQYLRSKSQLPLHHTSVKPQSQSPSIEATLVSELNQFEAELDSEIRGLERKLSQKQYQRPGRGEVKANAPATRTGEKRQENSSPIIPCSAVKQGITSSFMHADDHISSKMDFPPKKEERKMKAARAKFNFQAQSPKELTIQKGDVVYIHRQIDANWYEGEHHGRVGIFPTSYVEIIPPTEKPTPIKSPTIQVLEYGEAAALYTFNADLPVELSFRKGEVISITRRVDDHWLEGRIAGTTRSGIFPISYVQVNKMPRTKSSDDFPSSPTLTPEPLSPGRPQHSPLSPLSRSPEPQLSHHKQSSQSRSPLSHAQATSPKQPTNHFLFSPGPTSSTSPTSKRTGLMHLHNTPETDSRSPVSPSSHVLQSLQGPGLPAKHASPYITQDVARTQSSQPNTVISSTSQSPANMGHLRQPYKAVYNYKPQNRDELELREGDIVQVLEKCDDGWFVGTSERTEAFGTFPGNYVAPV", "length": 695 }, "evidence": [ { "id": "FB:FBgn0033504", "url": "https://alliancegenome.org/gene/FB:FBgn0033504#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O35413-1", "protein_name": "Sorbin and SH3 domain-containing protein 2", "gene_name": "Sorbs2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNTDSGGCARKRAAMSVTLTSVKRVQSSPNLLAAGRESHSPDSAWRSYNGRNPETLNGDATYSSLAAKGFRSVRPNLQDKKSPTQSHITINGNSGGAVSPVSYYQRPFSPSAYSLPASLNSSIIMPHGRSLDSAETYSQHAQSLDGTMGSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDEDTDMYNTPYTYNAGLYNSPYSAQSHPAAKTQTYRPLSKSHSDNGTDAFKEATSPVPPPHVPPRPRDQSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHERPVSVYQSSIDRSLERPSSSASMAGDFRKRRKSEPAVGPPRGLGDHSSSRTSPGRADLPGSSSTFTTSFISSSPSSPSRAQGGDDSKMCPPLCSYSGLNGSPSSELECCGAYRRHLDVPQDSQRAITFKNGWQMARQNAEIWSSTEEAVSPKIKSRSCDDLLNDDCGSFPDPKTKSESMGSLLCDEGSKESDPMTWTSPYIPEVCGNSRSRLKHRSAHNAPGFLKMYKKMHRINRKDLMNSEVICSVKSRILQYEKEQQHRGLLHGWSQSSTEEVPRDVVPTRISEFEKLIQKSKSMPNLGDEMLSPVTLEPPQNGLCPKRRFSIESLLEEETQVRHPSQGQRSCKSNTLVPIHIEVTSDEQPRTHMEFSDSDQDGVVSDHSDNVHVERSSFCSESDFDHFSFTSSESFYGSSHHHHHHHHHHGHFISSCKGRCPASYTRFTTMLKHERAKHENIDRPRRQDMDPGLSKLAFLVSPVPFRRKKVLTPQKQTEQAKCKASVVEALDSALKDICDQIKAEKRRGSLPDNSILHRLISELLPQIPKRNSSLNALKRSPMHQPFHPLPQDGAIHCPLYQNDCGRMPHSASFPDVDTTSSYHAQDYGSVLSLQDHESPRSYSSTLTDLGRSVSRERRGTPEKEVKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQPARPPPPVQPGEIGEAIAKYNFNADTNVELSLRKGDRIILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKRNTKGSEDYPDPPLPHSYSSDRIYSLSSNKPQRPVFSHENIQGGGEPFQALYNYTPRNEDELELRESDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1196 }, "evidence": [ { "id": "HGNC:24098", "url": "https://alliancegenome.org/gene/HGNC:24098#orthology", "database": "AGR" }, { "id": "RGD:620061", "url": "https://alliancegenome.org/gene/RGD:620061#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070308-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070308-3#orthology", "database": "AGR" }, { "id": "MGI:1924574", "url": "https://alliancegenome.org/gene/MGI:1924574#orthology", "database": "AGR" }, { "id": "FB:FBgn0033504", "url": "https://alliancegenome.org/gene/FB:FBgn0033504#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60504-1", "protein_name": "Vinexin", "gene_name": "SORBS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGPPRSLRAGLSLDDFIPGHLQSHIGSSSRGTRVPVIRNGGSNTLNFQFHDPAPRTVCNGGYTPRRDASQHPDPAWYQTWPGPGSKPSASTKIPASQHTQNWSATWTKDSKRRDKRWVKYEGIGPVDESGMPIAPRSSVDRPRDWYRRMFQQIHRKMPDLQLDWTFEEPPRDPRHLGAQQRPAHRPGPATSSSGRSWDHSEELPRSTFNYRPGAFSTVLQPSNQVLRRREKVDNVWTEESWNQFLQELETGQRPKKPLVDDPGEKPSQPIEVLLERELAELSAELDKDLRAIETRLPSPKSSPAPRRAPEQRPPAGPASAWSSSYPHAPYLGSARSLSPHKMADGGSPFLGRRDFVYPSSTRDPSASNGGGSPARREEKKRKAARLKFDFQAQSPKELTLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYVEVLPADEIPKPIKPPTYQVLEYGEAVAQYTFKGDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQGIFPASYVQVSREPRLRLCDDGPQLPTSPRLTAAARSARHPSSPSALRSPADPIDLGGQTSPRRTGFSFPTQEPRPQTQNLGTPGPALSHSRGPSHPLDLGTSSPNTSQIHWTPYRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV", "length": 671 }, "evidence": [ { "id": "FB:FBgn0033504", "url": "https://alliancegenome.org/gene/FB:FBgn0033504#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O94875-1", "protein_name": "Sorbin and SH3 domain-containing protein 2", "gene_name": "SORBS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYYQRPFSPSAYSLPASLNSSIVMQHGTSLDSTDTYPQHAQSLDGTTSSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPDDDTDMYNTPYTYNAGLYNPPYSAQSHPAAKTQTYRPLSKSHSDNSPNAFKDASSPVPPPHVPPPVPPLRPRDRSSTEKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHERPASLYQSSIDRSLERPMSSASMASDFRKRRKSEPAVGPPRGLGDQSASRTSPGRVDLPGSSTTLTKSFTSSSPSSPSRAKGGDDSKICPSLCSYSGLNGNPSSELDYCSTYRQHLDVPRDSPRAISFKNGWQMARQNAEIWSSTEETVSPKIKSRSCDDLLNDDCDSFPDPKVKSESMGSLLCEEDSKESCPMAWGSPYVPEVRSNGRSRIRHRSARNAPGFLKMYKKMHRINRKDLMNSEVICSVKSRILQYESEQQHKDLLRAWSQCSTEEVPRDMVPTRISEFEKLIQKSKSMPNLGDDMLSPVTLEPPQNGLCPKRRFSIEYLLEEENQSGPPARGRRGCQSNALVPIHIEVTSDEQPRAHVEFSDSDQDGVVSDHSDYIHLEGSSFCSESDFDHFSFTSSESFYGSSHHHHHHHHHHHRHLISSCKGRCPASYTRFTTMLKHERARHENTEEPRRQEMDPGLSKLAFLVSPVPFRRKKNSAPKKQTEKAKCKASVFEALDSALKDICDQIKAEKKRGSLPDNSILHRLISELLPDVPERNSSLRALRRSPLHQPLHPLPPDGAIHCPPYQNDCGRMPRSASFQDVDTANSSCHHQDRGGALQDRESPRSYSSTLTDMGRSAPRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQPARPPPPAQPGEIGEAIAKYNFNADTNVELSLRKGDRVILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKKNTKGAEDYPDPPIPHSYSSDRIHSLSSNKPQRPVFTHENIQGGGEPFQALYNYTPRNEDELELRESDVIDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1100 }, "evidence": [ { "id": "HGNC:24098", "url": "https://alliancegenome.org/gene/HGNC:24098#orthology", "database": "AGR" }, { "id": "RGD:620061", "url": "https://alliancegenome.org/gene/RGD:620061#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070308-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070308-3#orthology", "database": "AGR" }, { "id": "MGI:1924574", "url": "https://alliancegenome.org/gene/MGI:1924574#orthology", "database": "AGR" }, { "id": "FB:FBgn0033504", "url": "https://alliancegenome.org/gene/FB:FBgn0033504#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P29366-1", "protein_name": "Bud emergence protein 1", "gene_name": "BEM1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLKNFKLSKRDSNGSKGRITSADISTPSHDNGSVIKHIKTVPVRYLSSSSTPVKSQRDSSPKNRHNSKDITSPEKVIKAKYSYQAQTSKELSFMEGEFFYVSGDEKDWYKASNPSTGKEGVVPKTYFEVFDRTKPSSVNGSNSSSRKVTNDSLNMGSLYAIVLYDFKAEKADELTTYVGENLFICAHHNCEWFIAKPIGRLGGPGLVPVGFVSIIDIATGYATGNDVIEDIKSVNLPTVQEWKSNIARYKASNISLGSVEQQQQQSITKPQNKSAKLVDGELLVKASVESFGLEDEKYWFLVCCELSNGKTRQLKRYYQDFYDLQVQLLDAFPAEAGKLRDAGGQWSKRIMPYIPGPVPYVTNSITKKRKEDLNIYVADLVNLPDYISRSEMVHSLFVVLNNGFDREFERDENQNNIKTLQENDTATFATASQTSNFASTNQDNTLTGEDLKLNKKLSDLSLSGSKQAPAQSTSGLKTTKIKFYYKDDIFALMLKGDTTYKELRSKIAPRIDTDNFKLQTKLFDGSGEEIKTDSQVSNIIQAKLKISVHDI", "length": 551 }, "evidence": [ { "id": "HGNC:24098", "url": "https://alliancegenome.org/gene/HGNC:24098#orthology", "database": "AGR" }, { "id": "RGD:620061", "url": "https://alliancegenome.org/gene/RGD:620061#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3UTJ2-1", "protein_name": "Sorbin and SH3 domain-containing protein 2", "gene_name": "Sorbs2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNTDSGGCARKRAAMSVTLTSVKRVQSSPNLLAAGRESQSPDSAWRSYNDRNPETLNGDATYSSLAAKGFRSVRPNLQDKRSPTQSQITINGNSGGAVSPVSYYQRPFSPSAYSLPASLNSSIIMQHGRSLDSAETYSQHAQSLDGTMGSSIPLYRSSEEEKRVTVIKAPHYPGIGPVDESGIPTAIRTTVDRPKDWYKTMFKQIHMVHKPGLYNSPYSAQSHPAAKTQTYRPLSKSHSDNGTDAFKEVPSPVPPPHVPPRPRDQSSTLKHDWDPPDRKVDTRKFRSEPRSIFEYEPGKSSILQHERPVSIYQSSIDRSLERPSSSASMAGDFRKRRKSEPAVGPLRGLGDQSSSRTSPGRADLPGSSSTFTKSFISSSPSSPSRAQGGDDSKMCPPLCSYSGLNGTPSGELECCNAYRQHLDVPGDSQRAITFKNGWQMARQNAEIWSSTEETVSPKIKSRSCDDLLNDDCDSFPDPKTKSESMGSLLCEEDSKESCPMTWASPYIQEVCGNSRSRLKHRSAHNAPGFLKMYKKMHRINRKDLMNSEVICSVKSRILQYEKEQQHRGLLHGWSQSSTEEVPRDVVPTRISEFEKLIQKSKSMPNLGDEMLSPITLEPPQNGLCPKRRFSIESLLEEETQVRHPSQGQRSCKSNTLVPIHIEVTSDEQPRTHMEFSDSDQDGVVSDHSDYVHVEGSSFCSESDFDHFSFTSSESFYGSSHHHHHHHHHHRHLISSCKGRCPASYTRFTTMLKHERAKHENMDRPRRQEMDPGLSKLAFLVSPVPFRRKKILTPQKQTEKAKCKASVVEALDSALKDICDQIKAEKRRGSLPDNSILHRLISELLPQIPERNSSLHALKRSPMHQPFHPLPPDGASHCPLYQNDCGRMPHSASFPDVDTTSNYHAQDYGSALSLQDHESPRSYSSTLTDLGRSASRERRGTPEKEKLPAKAVYDFKAQTSKELSFKKGDTVYILRKIDQNWYEGEHHGRVGIFPISYVEKLTPPEKAQPARPPPPVQPGEIGEAIAKYNFNADTNVELSLRKGDRIILLKRVDQNWYEGKIPGTNRQGIFPVSYVEVVKRNAKGAEDYPDPPLPHSYSSDRIYTLSSNKPQRPGFSHENIQGGGEPFQALYNYTPRNEDELELRESDVVDVMEKCDDGWFVGTSRRTKFFGTFPGNYVKRL", "length": 1180 }, "evidence": [ { "id": "HGNC:24098", "url": "https://alliancegenome.org/gene/HGNC:24098#orthology", "database": "AGR" }, { "id": "RGD:620061", "url": "https://alliancegenome.org/gene/RGD:620061#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070308-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070308-3#orthology", "database": "AGR" }, { "id": "MGI:1924574", "url": "https://alliancegenome.org/gene/MGI:1924574#orthology", "database": "AGR" }, { "id": "FB:FBgn0033504", "url": "https://alliancegenome.org/gene/FB:FBgn0033504#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9R1Z8-1", "protein_name": "Vinexin", "gene_name": "Sorbs3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARILGVGRSSASSLNNKEDNESDVALLSPKDPNRVHTKEQLAHPASSNLDPSMQGLPAGLSLDDFIPGHLRTHIGSSSRGTRVPVIRNGGSNTLNFQFHDPAPRTVCNGCPPPRRDGSLNPDPAWYQTWPGPGSRPSMSPKPPASQHAQNWSATWTKDSKRQDKRWVKYEGIGPVDESGMPIAPRSSVDSPRDWYRRMFQQIHRKMPDLQLDWTLEDPPKVVSARASSAEPRHLGTLQRPASRPGTTETSSGRNWNHSEETSRNTFNYNFRPSSSGLHPPNQVPRHREKVENVWTEDSWNQFLHELETGHKPKKPLVDDPVEKPAQPIEVLLERELAKLSAELDKDLRAIETRLPSPKNSQAPRRPLEQPGLEQQPSARLSSAWRPNSPHAPYFSSSRPLSPHRMADGGGSPFLGRRDFVYPSSAREPSASERGSSPSRKEEKKRKAARLKFDFQAQSPKELSLQKGDIVYIHKEVDKNWLEGEHHGRLGIFPANYVEVLPADEIPKPIKPPTYQVLEYGDAVAQYTFKGDLEVELSFRKGERICLIRKVNEHWYEGRITGTGRQGIFPASYVQINREPRLRLCDDGPQLPASPNPTTTAHLSSHSHPSSIPVDPTDWGGRTSPRRSAFPFPITLQEPRSQTQSLNTPGPTLSHPRATSRPINLGPSSPNTEIHWTPYRAMYQYRPQNEDELELREGDRVDVMQQCDDGWFVGVSRRTQKFGTFPGNYVAPV", "length": 733 }, "evidence": [ { "id": "FB:FBgn0033504", "url": "https://alliancegenome.org/gene/FB:FBgn0033504#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "anchoring junction", "id": "GO:0070161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070161", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PN75", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PN75", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of heart rate", "id": "GO:0002027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002027", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PN75", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75" } ], "pmid": "" }, { "name": "cytoskeleton organization", "id": "GO:0007010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007010", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PN75", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PN75", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1052, "end_pos": 1054, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1113, "end_pos": 1115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1183, "end_pos": 1185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1626, "end_pos": 1628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1655, "end_pos": 1657, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1744, "end_pos": 1746, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1749, "end_pos": 1751, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 815, "end_pos": 817, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 1204, "end_pos": 1263, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PN75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN75" }, { "id": "PS50831", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50831" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SoHo", "eco_id": "ECO_0000259", "start_pos": 365, "end_pos": 433, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 102, 1416, 1420, 1500 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1052, "end_pos": 1054 }, { "start_pos": 1113, "end_pos": 1115 }, { "start_pos": 1183, "end_pos": 1185 }, { "start_pos": 1626, "end_pos": 1628 }, { "start_pos": 1655, "end_pos": 1657 }, { "start_pos": 1744, "end_pos": 1746 }, { "start_pos": 1749, "end_pos": 1751 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 681, "end_pos": 683 }, { "start_pos": 815, "end_pos": 817 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PK42-1", "uniprot_ac": "A0A8M9PK42", "uniprot_id": "A0A8M9PK42_DANRE", "mass": { "chemical_mass": 103232.0, "monoisotopic_mass": 103232.0 }, "refseq": { "ac": "XP_021322611", "name": "gamma-aminobutyric acid type B receptor subunit 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322611" }, "gene_names": [ { "name": "LOC560647", "type": "recommended", "evidence": [ { "id": "A0A8M9PK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42" } ] }, { "name": "LOC560647", "type": "synonym", "evidence": [ { "id": "XP_021322611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322611" } ] } ], "protein_names": [ { "name": "Gamma-aminobutyric acid type B receptor subunit 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42/entry#names_and_taxonomy" } ] }, { "name": "gamma-aminobutyric acid type B receptor subunit 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322611", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322611" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322611", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322611" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC560647", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42", "locus": {} } ], "crossref": [ { "id": "A0A8M9PK42", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PK42", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06366", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06366", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "560647", "url": "https://www.ncbi.nlm.nih.gov/gene/560647", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:560647", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560647", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PK42", "url": "https://www.orthodb.org/?gene=A0A8M9PK42", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10519", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10519", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10519:SF74", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10519:SF74", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322611", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322611", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9NZR0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9NZR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9NZR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PK42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PK42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HJY3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HJY3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HJY3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HJY3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEYWWSLLHVIFFWELTRVPLCYCLVRQKLPVLWIMPLSGAPGKGNITAEVLPAVELALQHLSEQTSNLANYELQFHLTDSECDNSKALKAFFETIFSGPKPLMIFGGACSSVTSVLAQSLESWNLVQLSFAVTVPLLADKRRFPNFFRTVPSDSAVNVALVRFLRQYGWSRVGTLTQREQSFTEVQTDLNRHLEEANIQLAEAESFSEAPCDCVKKLKDNDVRIVIAHFDQSLAAKVFCCIYNVKMYGQKYQWILPEWVQSSRWTDIDSTNCTSENILTAIEGSISADIESLSSSHIRGISGRTPQEYEKEYNERRQMKQLGGSKFHGFAYDGTWVIAKALTRVMETVKYRERYSVHRNFTLTDQEVGQMILEAMDKINFFGVTGHVMFQKGERVANVKFAQYQDGKAVDIEKYSAITDELEFISPIRFHKDKPTKDRTHVYPHRKRISILLYAIVSFLTFLGIFTACIFLVFSLKHRSHWAISMSRPLMNSLIILGAVLSYSSIFFMGLDGSYVSDRVFEVSCTVQISCLSIGCTTAFGAMFAKIWQIHLFFKNHSIDKKNTKNYGPNLLVILLFLIDLSLLISLQVLDPFRRTVKEYRIQPHPHGQDFFIQPFSERCENTHGLFWMAAFYIYKGTLLLSTCFLAWSTRHMNIPAVNDSRSIRFSVFVSVPVILIGTCASMFWQHRPNVQFCIVTLVIVTCCCCTLCMVFVPKIIIIRMGPDPAFLSRRFHLKQWHSELEKETEQNKDKRCMLEQRDPGLSVFMIDATLSISSSLTIHQSENLYLRRHINYLDSELEDLTRQLNLNETSAHAMEKVIVTGFVHKTAKDKCLTLPESSRCDRNLHQDINSPEHVRRRLSLQLPILHHAYLPSVGGVMEDSSPLYSPLQTPTTGSYGLLLTGL", "length": 903, "header": "tr|A0A8M9PK42-1|A0A8M9PK42_DANRE Isoform 1 of Gamma-aminobutyric acid type B receptor subunit 2 isoform X1 OS=Danio rerio OX=7955 GN=LOC560647 PE=3 SV=1 CANONICAL=A0A8M9PK42-1" }, "isoforms": [ { "isoform_ac": "A0A8M9NZR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42/entry#A0A8M9NZR0-1", "sequence": { "sequence": "MEYWWSLLHVIFFWELTRVPLCYCLVRQKLPVLWIMPLSGAPGKGNITAEVLPAVELALQHLSEQTSNLANYELQFHLTDSECDNSKALKAFFETIFSGPKPLMIFGGACSSVTSVLAQSLESWNLVQLSFAVTVPLLADKRRFPNFFRTVPSDSAVNVALVRFLRQYGWSRVGTLTQREQSFTEVQTDLNRHLEEANIQLAEAESFSEAPCDCVKKLKIYNVKMYGQKYQWILPEWVQSSRWTDIDSTNCTSENILTAIEGSISADIESLSSSHIRGISGRTPQEYEKEYNERRQMKQLGGSKFHGFAYDGTWVIAKALTRVMETVKYRERYSVHRNFTLTDQEVGQMILEAMDKINFFGVTGHVMFQKGERVANVKFAQYQDGKAVDIEKYSAITDELEFISPIRFHKDKPTKDRTHVYPHRKRISILLYAIVSFLTFLGIFTACIFLVFSLKHRSHWAISMSRPLMNSLIILGAVLSYSSIFFMGLDGSYVSDRVFEVSCTVQISCLSIGCTTAFGAMFAKIWQIHLFFKNHSIDKKNTKNYGPNLLVILLFLIDLSLLISLQVLDPFRRTVKEYRIQPHPHGQDFFIQPFSERCENTHGLFWMAAFYIYKGTLLLSTCFLAWSTRHMNIPAVNDSRSIRFSVFVSVPVILIGTCASMFWQHRPNVQFCIVTLVIVTCCCCTLCMVFVPKIIIIRMGPDPAFLSRRFHLKQWHSELEKETEQNKDKRCMLEQRDPGLSVFMIDATLSISSSLTIHQSENLYLRRHINYLDSELEDLTRQLNLNETSAHAMEKVIVTGFVHKTAKDKCLTLPESSRCDRNLHQDINSPEHVRRRLSLQLPILHHAYLPSVGGVMEDSSPLYSPLQTPTTGSYGLLLTGL", "length": 881, "header": "tr|A0A8M9NZR0-1|A0A8M9PK42_DANRE Computationally mapped isoform of Gamma-aminobutyric acid type B receptor subunit 2 isoform X1 OS=Danio rerio OX=7955 GN=LOC560647 PE=3 SV=1 CANONICAL=A0A8M9PK42-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PK42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42/entry#A0A8M9PK42-1", "sequence": { "sequence": "MEYWWSLLHVIFFWELTRVPLCYCLVRQKLPVLWIMPLSGAPGKGNITAEVLPAVELALQHLSEQTSNLANYELQFHLTDSECDNSKALKAFFETIFSGPKPLMIFGGACSSVTSVLAQSLESWNLVQLSFAVTVPLLADKRRFPNFFRTVPSDSAVNVALVRFLRQYGWSRVGTLTQREQSFTEVQTDLNRHLEEANIQLAEAESFSEAPCDCVKKLKDNDVRIVIAHFDQSLAAKVFCCIYNVKMYGQKYQWILPEWVQSSRWTDIDSTNCTSENILTAIEGSISADIESLSSSHIRGISGRTPQEYEKEYNERRQMKQLGGSKFHGFAYDGTWVIAKALTRVMETVKYRERYSVHRNFTLTDQEVGQMILEAMDKINFFGVTGHVMFQKGERVANVKFAQYQDGKAVDIEKYSAITDELEFISPIRFHKDKPTKDRTHVYPHRKRISILLYAIVSFLTFLGIFTACIFLVFSLKHRSHWAISMSRPLMNSLIILGAVLSYSSIFFMGLDGSYVSDRVFEVSCTVQISCLSIGCTTAFGAMFAKIWQIHLFFKNHSIDKKNTKNYGPNLLVILLFLIDLSLLISLQVLDPFRRTVKEYRIQPHPHGQDFFIQPFSERCENTHGLFWMAAFYIYKGTLLLSTCFLAWSTRHMNIPAVNDSRSIRFSVFVSVPVILIGTCASMFWQHRPNVQFCIVTLVIVTCCCCTLCMVFVPKIIIIRMGPDPAFLSRRFHLKQWHSELEKETEQNKDKRCMLEQRDPGLSVFMIDATLSISSSLTIHQSENLYLRRHINYLDSELEDLTRQLNLNETSAHAMEKVIVTGFVHKTAKDKCLTLPESSRCDRNLHQDINSPEHVRRRLSLQLPILHHAYLPSVGGVMEDSSPLYSPLQTPTTGSYGLLLTGL", "length": 903, "header": "tr|A0A8M9PK42-1|A0A8M9PK42_DANRE Isoform 1 of Gamma-aminobutyric acid type B receptor subunit 2 isoform X1 OS=Danio rerio OX=7955 GN=LOC560647 PE=3 SV=1 CANONICAL=A0A8M9PK42-1" }, "locus": {} }, { "isoform_ac": "A0AC58HJY3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42/entry#A0AC58HJY3-1", "sequence": { "sequence": "MKQLGGSKFHGFAYDGTWVIAKALTRVMETVKYRERYSVHRNFTLTDQEVGQMILEAMDKINFFGVTGHVMFQKGERVANVKFAQYQDGKAVDIEKYSAITDELEFISPIRFHKDKPTKDRTHVYPHRKRISILLYAIVSFLTFLGIFTACIFLVFSLKHRSHWAISMSRPLMNSLIILGAVLSYSSIFFMGLDGSYVSDRVFEVSCTVQISCLSIGCTTAFGAMFAKIWQIHLFFKNHSIDKKNTKNYGPNLLVILLFLIDLSLLISLQVLDPFRRTVKEYRIQPHPHGQDFFIQPFSERCENTHGLFWMAAFYIYKGTLLLSTCFLAWSTRHMNIPAVNDSRSIRFSVFVSVPVILIGTCASMFWQHRPNVQFCIVTLVIVTCCCCTLCMVFVPKIIIIRMGPDPAFLSRRFHLKQWHSELEKETEQNKDKRCMLEQRDPGLSVFMIDATLSISSSLTIHQSENLYLRRHINYLDSELEDLTRQLNLNETSAHAMEKVIVTGFVHKTAKDKCLTLPESSRCDRNLHQDINSPEHVRRRLSLQLPILHHAYLPSVGGVMEDSSPLYSPLQTPTTGSYGLLLTGL", "length": 585, "header": "tr|A0AC58HJY3-1|A0AC58HJY3_DANRE Computationally mapped isoform of Gamma-aminobutyric acid type B receptor subunit 2 isoform X3 OS=Danio rerio OX=7955 GN=LOC560647 PE=3 SV=1 CANONICAL=A0A8M9PK42-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:560647", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560647", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42" } ], "pmid": "" }, { "name": "G protein-coupled receptor heterodimeric complex", "id": "GO:0038039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038039", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled GABA receptor activity", "id": "GO:0004965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004965", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "gamma-aminobutyric acid signaling pathway", "id": "GO:0007214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007214", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 360, "end_pos": 362, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 659, "end_pos": 661, "annotation": "n_glycosylation_sequon" }, { "start_pos": 808, "end_pos": 810, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PK42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK42" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 523, "end_pos": 735, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 272, "end_pos": 274 }, { "start_pos": 360, "end_pos": 362 }, { "start_pos": 46, "end_pos": 48 }, { "start_pos": 556, "end_pos": 558 }, { "start_pos": 659, "end_pos": 661 }, { "start_pos": 808, "end_pos": 810 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPX4-1", "uniprot_ac": "A0A8M9PPX4", "uniprot_id": "A0A8M9PPX4_DANRE", "mass": { "chemical_mass": 78928.0, "monoisotopic_mass": 78928.0 }, "refseq": { "ac": "XP_021324306", "name": "uncharacterized protein mylk4b isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324306" }, "gene_names": [ { "name": "mylk4b", "type": "recommended", "evidence": [ { "id": "A0A8M9PPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4" } ] }, { "name": "mylk4b", "type": "synonym", "evidence": [ { "id": "XP_021324306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324306" } ] } ], "protein_names": [ { "name": "Uncharacterized protein mylk4b isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein mylk4b isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021324306", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324306" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324306", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324306" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mylk4b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041001-128", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-128", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PPX4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PPX4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000055412", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000055412", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14193", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14193", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "449707", "url": "https://www.ncbi.nlm.nih.gov/gene/449707", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:449707", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449707", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HIEGQVN", "url": "https://omabrowser.org/oma/group/HIEGQVN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PPX4", "url": "https://www.orthodb.org/?gene=A0A8M9PPX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "Q1LVG0", "url": "https://www.orthodb.org/?gene=Q1LVG0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24342", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24342", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24342:SF20", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24342:SF20", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021324306", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324306", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9P2Y5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P2Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P2Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PC81", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PC81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PC81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PHU7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PHU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T788", "url": "https://www.uniprot.org/uniprotkb/A0AB32T788", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T788-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T788-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I571", "url": "https://www.uniprot.org/uniprotkb/A0AC58I571", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I571-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I571-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I583", "url": "https://www.uniprot.org/uniprotkb/A0AC58I583", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I583-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I583-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I585", "url": "https://www.uniprot.org/uniprotkb/A0AC58I585", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I585-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I585-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q1LVG0", "url": "https://www.uniprot.org/uniprotkb/Q1LVG0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "Q1LVG0-1", "url": "https://www.uniprot.org/uniprotkb/Q1LVG0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041001-128", "url": "https://zfin.org/ZDB-GENE-041001-128", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSNLVKSLARVYDPKPLHAQKRHNSGRAGARRASLSTSNKCSSSPVLDQPTSKSSLVHIEGQVNDLSGKMDKLLALQEASLKRLDAIGQEHSTGGRSVEQMLCDVRVVIETVREKEEQQDQRLDALERLVSSIQQVVSFVAEALKQESLADHLKNTNSKSSSRFREKDGKEKSKGYPKGLKTQKKKKPLDASDSVQAGFEEVQKLNQQNNQLSQCTAETAAGTSTQLEIIKEAQTTEIFREIKDDAQQAVVEEETREKESIAELLQVTGEDKKEEEERVQKEEDIRLTEESQLAAPTSSGQNDKIITATPESCEENLEIILSTKRHVSDESLTDDLKKSRVEEEEEEEKELKEEEEEAGLEAAEAGPEEETEEERKDAEAVTDEYVIDSSPPPPAPFEHRLVSTKTHQITSYYNINKEEVLGGGRFGIVHKCEEKSSGLILAAKIIKARSQKEKEVVKCEIEVMNQLNHANLIQLYAAFESRHEITLVMEYVDGGELFERIIDENYKLTELDTVLFIRQITEGLQYMHKMYILHLDLKPENILCISRETNKVKIIDFGLARRYKPREKLRVNFGTPEFLAPEVINYEFVSFPTDMWSLGVITYMLLSGLSPFLGEDDNETLNNILACQWSFEEAEFADISEEAKDFISRLLVKSKSWRMSASQSLKHPWLSDRGLHYRLHHKKNKCHSSHAPPPEG", "length": 697, "header": "tr|A0A8M9PPX4-1|A0A8M9PPX4_DANRE Isoform 1 of Uncharacterized protein mylk4b isoform X1 OS=Danio rerio OX=7955 GN=mylk4b PE=3 SV=1 CANONICAL=A0A8M9PPX4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P2Y5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4/entry#A0A8M9P2Y5-1", "sequence": { "sequence": "MSSNLVKSLARVYDPKPLHAQKRHNSGRAGARRASLSTSNKCSSSPVLDQPTSKSSLVHIEGQVNDLSGKMDKLLALQEASLKRLDAIGQEHSTGGRSVEQMLCDVRVVIETVREKEEQQDQRLDALERLVSSIQQVVSFVAEALKQESLADHLKNTNSKSSSRFREKDGKEKSKGYPKGLKTQKKKKPLDASDSVQAGFEEVQKLNQQNNQLSQCTAETAAGTSTQLEIIKEAQTTEIFREIKDDAQQAVVEEETREKESIAELLQVTGEDKKEEEERVQKEEDIRLTEESQLAAPTSSGQNDKIITATPESRVEEEEEEEKELKEEEEEAGLEAAEAGPEEETEEERKDAEAVTDEYVIDSSPPPPAPFEHRLVSTKTHQITSYYNINKEEVLGGGRFGIVHKCEEKSSGLILAAKIIKARSQKEKEVVKCEIEVMNQLNHANLIQLYAAFESRHEITLVMEYVDGGELFERIIDENYKLTELDTVLFIRQITEGLQYMHKMYILHLDLKPENILCISRETNKVKIIDFGLARRYKPREKLRVNFGTPEFLAPEVINYEFVSFPTDMWSLGVITYMLLSGLSPFLGEDDNETLNNILACQWSFEEAEFADISEEAKDFISRLLVKSKSWRMSASQSLKHPWLSDRGLHYRLHHKKNKCHSSHAPPPEG", "length": 670, "header": "tr|A0A8M9P2Y5-1|A0A8M9PPX4_DANRE Computationally mapped isoform of Uncharacterized protein mylk4b isoform X1 OS=Danio rerio OX=7955 GN=mylk4b PE=3 SV=1 CANONICAL=A0A8M9PPX4-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PC81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4/entry#A0A8M9PC81-1", "sequence": { "sequence": "MSSNLVKSLARVYDPKPLHAQKRHNSGRAGARRASLSTSNKCSSSPVLDQPTSKSSLVHIEGQVNDLSGKMDKLLALQEASLKRLDAIGQEHSTGGRSVEQMLCDVRVVIETVREKEEQQDQRLDALERLVSSIQQVVSFVAEALKQESLADHLKNTNSKSSSRFREKDGKEKSKGYPKGLKTQKKKKPLDASDSVQAGFEEVQKLNQQNNQLSQCTAETAAGTSTQLEIIKEAQTTEIFREIKDDAQQAVVEEETREKESIAELLQVTGEDKKEEEERVQKEEDIRLTEESQLAAPTSSGQNDKIITATPERVEEEEEEEKELKEEEEEAGLEAAEAGPEEETEEERKDAEAVTDEYVIDSSPPPPAPFEHRLVSTKTHQITSYYNINKEEVLGGGRFGIVHKCEEKSSGLILAAKIIKARSQKEKEVVKCEIEVMNQLNHANLIQLYAAFESRHEITLVMEYVDGGELFERIIDENYKLTELDTVLFIRQITEGLQYMHKMYILHLDLKPENILCISRETNKVKIIDFGLARRYKPREKLRVNFGTPEFLAPEVINYEFVSFPTDMWSLGVITYMLLSGLSPFLGEDDNETLNNILACQWSFEEAEFADISEEAKDFISRLLVKSKSWRMSASQSLKHPWLSDRGLHYRLHHKKNKCHSSHAPPPEG", "length": 669, "header": "tr|A0A8M9PC81-1|A0A8M9PPX4_DANRE Computationally mapped isoform of Uncharacterized protein mylk4b isoform X1 OS=Danio rerio OX=7955 GN=mylk4b PE=3 SV=1 CANONICAL=A0A8M9PPX4-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PHU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4/entry#A0A8M9PHU7-1", "sequence": { "sequence": "MEGDDSQTKELDVGRLAFFGHLEQVEKMRCYWELKHVQRKTLEQFREKDGKEKSKGYPKGLKTQKKKKPLDASDSVQAGFEEVQKLNQQNNQLSQCTAETAAGTSTQLEIIKEAQTTEIFREIKDDAQQAVVEEETREKESIAELLQVTGEDKKEEEERVQKEEDIRLTEESQLAAPTSSGQNDKIITATPESCEENLEIILSTKRHVSDESLTDDLKKSRVEEEEEEEKELKEEEEEAGLEAAEAGPEEETEEERKDAEAVTDEYVIDSSPPPPAPFEHRLVSTKTHQITSYYNINKEEVLGGGRFGIVHKCEEKSSGLILAAKIIKARSQKEKEVVKCEIEVMNQLNHANLIQLYAAFESRHEITLVMEYVDGGELFERIIDENYKLTELDTVLFIRQITEGLQYMHKMYILHLDLKPENILCISRETNKVKIIDFGLARRYKPREKLRVNFGTPEFLAPEVINYEFVSFPTDMWSLGVITYMLLSGLSPFLGEDDNETLNNILACQWSFEEAEFADISEEAKDFISRLLVKSKSWRMSASQSLKHPWLSDRGLHYRLHHKKNKCHSSHAPPPEG", "length": 577, "header": "tr|A0A8M9PHU7-1|A0A8M9PPX4_DANRE Computationally mapped isoform of Uncharacterized protein mylk4b isoform X1 OS=Danio rerio OX=7955 GN=mylk4b PE=3 SV=1 CANONICAL=A0A8M9PPX4-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PPX4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4/entry#A0A8M9PPX4-1", "sequence": { "sequence": "MSSNLVKSLARVYDPKPLHAQKRHNSGRAGARRASLSTSNKCSSSPVLDQPTSKSSLVHIEGQVNDLSGKMDKLLALQEASLKRLDAIGQEHSTGGRSVEQMLCDVRVVIETVREKEEQQDQRLDALERLVSSIQQVVSFVAEALKQESLADHLKNTNSKSSSRFREKDGKEKSKGYPKGLKTQKKKKPLDASDSVQAGFEEVQKLNQQNNQLSQCTAETAAGTSTQLEIIKEAQTTEIFREIKDDAQQAVVEEETREKESIAELLQVTGEDKKEEEERVQKEEDIRLTEESQLAAPTSSGQNDKIITATPESCEENLEIILSTKRHVSDESLTDDLKKSRVEEEEEEEKELKEEEEEAGLEAAEAGPEEETEEERKDAEAVTDEYVIDSSPPPPAPFEHRLVSTKTHQITSYYNINKEEVLGGGRFGIVHKCEEKSSGLILAAKIIKARSQKEKEVVKCEIEVMNQLNHANLIQLYAAFESRHEITLVMEYVDGGELFERIIDENYKLTELDTVLFIRQITEGLQYMHKMYILHLDLKPENILCISRETNKVKIIDFGLARRYKPREKLRVNFGTPEFLAPEVINYEFVSFPTDMWSLGVITYMLLSGLSPFLGEDDNETLNNILACQWSFEEAEFADISEEAKDFISRLLVKSKSWRMSASQSLKHPWLSDRGLHYRLHHKKNKCHSSHAPPPEG", "length": 697, "header": "tr|A0A8M9PPX4-1|A0A8M9PPX4_DANRE Isoform 1 of Uncharacterized protein mylk4b isoform X1 OS=Danio rerio OX=7955 GN=mylk4b PE=3 SV=1 CANONICAL=A0A8M9PPX4-1" }, "locus": {} }, { "isoform_ac": "A0AB32T788-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4/entry#A0AB32T788-1", "sequence": { "sequence": "MEGDDSQTKELDVGRLAFFGHLEQVEKMRCYWELKHVQRKTLEQFREKDGKEKSKGYPKGLKTQKKKKPLDASDSVQAGFEEVQKLNQQNNQLSQCTAETAAGTSTQLEIIKEAQTTEIFREIKDDAQQAVVEEETREKESIAELLQVTGEDKKEEEERVQKEEDIRLTEESQLAAPTSSGQNDKIITATPERVEEEEEEEKELKEEEEEAGLEAAEAGPEEETEEERKDAEAVTDEYVIDSSPPPPAPFEHRLVSTKTHQITSYYNINKEEVLGGGRFGIVHKCEEKSSGLILAAKIIKARSQKEKEVVKCEIEVMNQLNHANLIQLYAAFESRHEITLVMEYVDGGELFERIIDENYKLTELDTVLFIRQITEGLQYMHKMYILHLDLKPENILCISRETNKVKIIDFGLARRYKPREKLRVNFGTPEFLAPEVINYEFVSFPTDMWSLGVITYMLLSGLSPFLGEDDNETLNNILACQWSFEEAEFADISEEAKDFISRLLVKSKSWRMSASQSLKHPWLSDRGLHYRLHHKKNKCHSSHAPPPEG", "length": 549, "header": "tr|A0AB32T788-1|A0A8M9PPX4_DANRE Computationally mapped isoform of Uncharacterized protein mylk4b isoform X1 OS=Danio rerio OX=7955 GN=mylk4b PE=3 SV=1 CANONICAL=A0A8M9PPX4-1" }, "locus": {} }, { "isoform_ac": "A0AC58I571-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4/entry#A0AC58I571-1", "sequence": { "sequence": "MENFLQDKDLWIVGSVCLVASILWRRFWNLFTYKRKRESSPESASIDIEFREKDGKEKSKGYPKGLKTQKKKKPLDASDSVQAGFEEVQKLNQQNNQLSQCTAETAAGTSTQLEIIKEAQTTEIFREIKDDAQQAVVEEETREKESIAELLQVTGEDKKEEEERVQKEEDIRLTEESQLAAPTSSGQNDKIITATPESRVEEEEEEEKELKEEEEEAGLEAAEAGPEEETEEERKDAEAVTDEYVIDSSPPPPAPFEHRLVSTKTHQITSYYNINKEEVLGGGRFGIVHKCEEKSSGLILAAKIIKARSQKEKEVVKCEIEVMNQLNHANLIQLYAAFESRHEITLVMEYVDGGELFERIIDENYKLTELDTVLFIRQITEGLQYMHKMYILHLDLKPENILCISRETNKVKIIDFGLARRYKPREKLRVNFGTPEFLAPEVINYEFVSFPTDMWSLGVITYMLLSGLSPFLGEDDNETLNNILACQWSFEEAEFADISEEAKDFISRLLVKSKSWRMSASQSLKHPWLSDRGLHYRLHHKKNKCHSSHAPPPEG", "length": 555, "header": "tr|A0AC58I571-1|A0AC58I571_DANRE Computationally mapped isoform of Myosin light chain kinase family member 4 isoform X6 OS=Danio rerio OX=7955 GN=mylk4b PE=3 SV=1 CANONICAL=A0A8M9PPX4-1" }, "locus": {} }, { "isoform_ac": "A0AC58I583-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4/entry#A0AC58I583-1", "sequence": { "sequence": "MENFLQDKDLWIVGSVCLVASILWRRFWNLFTYKRKRESSPESASIDIEFREKDGKEKSKGYPKGLKTQKKKKPLDASDSVQAGFEEVQKLNQQNNQLSQCTAETAAGTSTQLEIIKEAQTTEIFREIKDDAQQAVVEEETREKESIAELLQVTGEDKKEEEERVQKEEDIRLTEESQLAAPTSSGQNDKIITATPERVEEEEEEEKELKEEEEEAGLEAAEAGPEEETEEERKDAEAVTDEYVIDSSPPPPAPFEHRLVSTKTHQITSYYNINKEEVLGGGRFGIVHKCEEKSSGLILAAKIIKARSQKEKEVVKCEIEVMNQLNHANLIQLYAAFESRHEITLVMEYVDGGELFERIIDENYKLTELDTVLFIRQITEGLQYMHKMYILHLDLKPENILCISRETNKVKIIDFGLARRYKPREKLRVNFGTPEFLAPEVINYEFVSFPTDMWSLGVITYMLLSGLSPFLGEDDNETLNNILACQWSFEEAEFADISEEAKDFISRLLVKSKSWRMSASQSLKHPWLSDRGLHYRLHHKKNKCHSSHAPPPEG", "length": 554, "header": "tr|A0AC58I583-1|A0AC58I583_DANRE Computationally mapped isoform of Myosin light chain kinase family member 4 isoform X7 OS=Danio rerio OX=7955 GN=mylk4b PE=3 SV=1 CANONICAL=A0A8M9PPX4-1" }, "locus": {} }, { "isoform_ac": "A0AC58I585-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4/entry#A0AC58I585-1", "sequence": { "sequence": "MEGDDSQTKELDVGRLAFFGHLEQVEKMRCYWELKHVQRKTLEQFREKDGKEKSKGYPKGLKTQKKKKPLDASDSVQAGFEEVQKLNQQNNQLSQCTAETAAGTSTQLEIIKEAQTTEIFREIKDDAQQAVVEEETREKESIAELLQVTGEDKKEEEERVQKEEDIRLTEESQLAAPTSSGQNDKIITATPESRVEEEEEEEKELKEEEEEAGLEAAEAGPEEETEEERKDAEAVTDEYVIDSSPPPPAPFEHRLVSTKTHQITSYYNINKEEVLGGGRFGIVHKCEEKSSGLILAAKIIKARSQKEKEVVKCEIEVMNQLNHANLIQLYAAFESRHEITLVMEYVDGGELFERIIDENYKLTELDTVLFIRQITEGLQYMHKMYILHLDLKPENILCISRETNKVKIIDFGLARRYKPREKLRVNFGTPEFLAPEVINYEFVSFPTDMWSLGVITYMLLSGLSPFLGEDDNETLNNILACQWSFEEAEFADISEEAKDFISRLLVKSKSWRMSASQSLKHPWLSDRGLHYRLHHKKNKCHSSHAPPPEG", "length": 550, "header": "tr|A0AC58I585-1|A0AC58I585_DANRE Computationally mapped isoform of Myosin light chain kinase family member 4 isoform X8 OS=Danio rerio OX=7955 GN=mylk4b PE=3 SV=1 CANONICAL=A0A8M9PPX4-1" }, "locus": {} }, { "isoform_ac": "Q1LVG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4/entry#Q1LVG0-1", "sequence": { "sequence": "MENFLQDKDLWIVGSVCLVASILWRRFWNLFTYKRKRESSPESASIDIEFREKDGKEKSKGYPKGLKTQKKKKPLDASDSVQAGFEEVQKLNQQNNQLSQCTAETAAGTSTQLEIIKEAQTTEIFREIKDDAQQAVVEEETREKESIAELLQVTGEDKKEEEERVQKEEDIRLTEESQLAAPTSSGQNDKIITATPESCEENLEIILSTKRHVSDESLTDDLKKSRVEEEEEEEKELKEEEEEAGLEAAEAGPEEETEEERKDAEAVTDEYVIDSSPPPPAPFEHRLVSTKTHQITSYYNINKEEVLGGGRFGIVHKCEEKSSGLILAAKIIKARSQKEKEVVKCEIEVMNQLNHANLIQLYAAFESRHEITLVMEYVDGGELFERIIDENYKLTELDTVLFIRQITEGLQYMHKMYILHLDLKPENILCISRETNKVKIIDFGLARRYKPREKLRVNFGTPEFLAPEVINYEFVSFPTDMWSLGVITYMLLSGLSPFLGEDDNETLNNILACQWSFEEAEFADISEEAKDFISRLLVKSKSWRMSASQSLKHPWLSDRGLHYRLHHKKNKCHSSHAPPPEG", "length": 582, "header": "tr|Q1LVG0-1|A0A8M9PPX4_DANRE Computationally mapped isoform of Uncharacterized protein mylk4b isoform X1 OS=Danio rerio OX=7955 GN=mylk4b PE=3 SV=2 CANONICAL=A0A8M9PPX4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:449707", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449707", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7TBH3-1", "protein_name": "Uncharacterized protein mylk4a isoform X1", "gene_name": "mylk4a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSADANTGMDLLQVRIESLSSKMDRLISIQEKVLSRLDGMSQDIDGIERDVETLKVEKEEIHFPPVIRTGTGNQMKEMCEEMNSIMLAVNQRSEQQTQKLEGMEKLVMSIQQAVSFIGETVKTSKIMDIMFKGPASRKSKSAPGLKSKDSKIKPSSKCENSEAVSAKLKEPKGFHLSLKGLKAQRKKKPPDSAADKVFLRKQALLLEEVQKLNQENAERSKPAQTQDNDLQKSEDASVTPHLQDIILEEAKPVEDEPRKKTKVEKKVTLDLREEQKNIPETNTEEIREEMKKADTEEILLKTTEVLKDQKTDDTESKTTTEGPSEADNIDTKATEGPSEDVITDKETIEGPSEADITDTEPPTATENSEISSESEQADEVTTSSKRRVTEEDLGLEDHKKSRVEDGEQQEPEPPEPEDLRAVFKADGVEIQIDFSKLKQQSFEDEDDEDHGDHFFIDCTPPPAAPFNHRVVSAKPHQISTFYTINQQEVLGGGRYGQVHKCIENSSGLTLAAKIIKAKSQKEKEVVKNEIQVMNQLDHANLIQLYAAYESRNDIILVLEYVDGGELFDRIIDENYKLTELDTVMFIRQICEGLRYMHKMYILHLDLKPENILCVSRVTNKVKIIDFGLARKYQPREKLRVNFGTPEFLSPEVVNYDFVSFNTDMWSLGVITYMLLSGLSPFLGDDDNETLNNILACQWNFEEDEFSEVSAEAKDFISKLLVVDKSWRIGATEALRHPWLSDAAVHFRLHERKNKCRSRRNSCLPPPES", "length": 769 }, "evidence": [ { "id": "RGD:6494757", "url": "https://alliancegenome.org/gene/RGD:6494757#orthology", "database": "AGR" }, { "id": "RGD:1565323", "url": "https://alliancegenome.org/gene/RGD:1565323#orthology", "database": "AGR" }, { "id": "HGNC:27972", "url": "https://alliancegenome.org/gene/HGNC:27972#orthology", "database": "AGR" }, { "id": "MGI:3643758", "url": "https://alliancegenome.org/gene/MGI:3643758#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z7Y7-1", "protein_name": "2.7.11.18", "gene_name": "sqa", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIYIDDSEPEGVLEPAFPMRDVTINRNVDAHKHYDVLGEVGRGKFGTVYKCRDKANGLQLAAKFVPIPKREDKRNVEREVEIMNSLQHHLIIQLYAAYEYQKMMCVVLELIEGGELFDRVVDDEFVLTERVCRVFIRQVCEAMAFIHGNGIVHLDLKPENILVLTQKGNRIKIIDFGLARKFDPDKRLRVLFGTPEFVAPEVVNFDCISYGTDMWSVGVICYVLISGLSPFMGENDIETMSNVTIAKYDFEDECFNGISPECLDFIAKLLAKDLSTRMTAAECMKHKWLQQRPATAATATPITKAASAASKSRLKSVSPVTAPSESSEDSTETIEDEDDEEEVAVQQAKQKDQQQDEELANLCGDAELENKELDATKDNLKNFIVRWETHPNSPYVFDVEGNVIAPLSETSYPHPRRTHGADSLSSSRVCSPSPCDSISTLTDDERGDIEDLPEEDESRSAENESPRSVATPINESREKLFPTVATSSPSTPTPQHLFNENFDEFSGSQSTAQQQRSMKSYLHTFDRRNSDTTYLLGRRSSGERVNLADEIRKLSDHLLMLAEINTKLGDANNNGSSSGAPADPPAAAAAAAAPVPTSTAPASVAPSGSTSSKTSEISQEGNRWTSKTTSSSSWNRPTLKGGLFSQASSSSQSQSTYDDGKGKTKISSLSVRLQQSIEETPKLSNGNSSSSKSLVQSQRKSTVQTMSSSNARSFTNQQVQRTSTTSSKVISSSTRSSNTSSSNYIASNASNSISTSASNPSSTGASNPITTSASNESASSRRAKFRINQMSRDVPVGLPDTHQTVNLEEAANTTKDCLLHLLEKYNETRIRNPVGRHQSISVDWRVSDNLEYRSMSSINAFFQRHNPNGGGHNVRHIQAQLEEKAAGK", "length": 888 }, "evidence": [ { "id": "RGD:6494757", "url": "https://alliancegenome.org/gene/RGD:6494757#orthology", "database": "AGR" }, { "id": "RGD:1565323", "url": "https://alliancegenome.org/gene/RGD:1565323#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "M0R632-1", "protein_name": "Myosin light chain kinase family, member 4", "gene_name": "Mylk4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFPTKSADFAIFIHLIVFQNSQLDLLPPMLPLLGGGAEENVWSNHTLNERTIVRGGRTSALTERHDQKDQFSSEKEKITKLNKKNAEKTSGSEVQRTCVICHVERQDKIEFVQRNSTELREYAGTKDASCMESLEKQESNSLGYKQDTEDNNGGENGISSKEDSREIEAENRASTAASGTVLDKHSTESQHTEDMNGVQSHERSISNIKTISTPGILGNSASGPTLQNAEQTESTGSSKRRVAEECFLSEDNKKSRIDVVGAGEESIPRTEENRQARSLDNRLQDGMTTSREQDLAVQLDDVPAPAAPFDHRIVMAKHAAVDSLYSVSKSEILGGGRFGQVHKCEEKATGLKLAAKIIKIRGAKDKEDVKNEISVMNQLDHVNLIQLYDAFESKHDIILVMEYVEGGELFDRIIDENCNLTELDTILFVKQICEGIRYMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFATDMWSVGVITYMLLSGLSPFLGDNDAETLTNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHSRLSAQKNSNSGVLNLTTK", "length": 608 }, "evidence": [ { "id": "RGD:6494757", "url": "https://alliancegenome.org/gene/RGD:6494757#orthology", "database": "AGR" }, { "id": "RGD:1565323", "url": "https://alliancegenome.org/gene/RGD:1565323#orthology", "database": "AGR" }, { "id": "HGNC:27972", "url": "https://alliancegenome.org/gene/HGNC:27972#orthology", "database": "AGR" }, { "id": "MGI:3643758", "url": "https://alliancegenome.org/gene/MGI:3643758#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-128", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-128#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38623-1", "protein_name": "Serine/threonine-protein kinase RCK2", "gene_name": "RCK2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MLKIKALFSKKKPDQADLSQESKKPFKGKTRSSGTNNKDVSQITSSPKKSFQDKNIVQYPSVVADDHHMKSLTDELVTTIDSDSSPSDNITTENVETVTSVPAIDVHESSEGQLSSDPLISDESLSEQSEIISDIQDDSTDDDNMEDEIPEKSFLEQKELIGYKLINKIGEGAFSKVFRAIPAKNSSNEFLTKNYKAVAIKVIKKADLSSINGDHRKKDKGKDSTKTSSRDQVLKEVALHKTVSAGCSQIVAFIDFQETDSYYYIIQELLTGGEIFGEIVRLTYFSEDLSRHVIKQLALAVKHMHSLGVVHRDIKPENLLFEPIEFTRSIKPKLRKSDDPQTKADEGIFTPGVGGGGIGIVKLADFGLSKQIFSKNTKTPCGTVGYTAPEVVKDEHYSMKVDMWGIGCVLYTMLCGFPPFYDEKIDTLTEKISRGEYTFLKPWWDEISAGAKNAVAKLLELEPSKRYDIDQFLDDPWLNTFDCLPKEGESSQKKAGTSERRHPHKKQFQLFQRDSSLLFSPAAVAMRDAFDIGNAVKRTEEDRMGTRGGLGSLAEDEELEDSYSGAQGDEQLEQNMFQLTLDTSTILQRRKKVQENDVGPTIPISATIRE", "length": 610 }, "evidence": [ { "id": "RGD:6494757", "url": "https://alliancegenome.org/gene/RGD:6494757#orthology", "database": "AGR" }, { "id": "RGD:1565323", "url": "https://alliancegenome.org/gene/RGD:1565323#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5SUV5-1", "protein_name": "Myosin light chain kinase family member 4", "gene_name": "Mylk4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKVKRLEEISSCHSSNPLEKVAFFQCMEEVEKVKCFLEENSGDLDLQSGDNEAEENVWSNRALDERIIVKGGRTSALTDDIPAPAAPFDHRMVMAKHASVDNLYTVSKSEILGGGRFGQVHKCEEKATGLKLAAKIIKTRGAKDKEDVKNEISVMNQLDHVNLIQLYDAFESKHDIILVMDVEGGELFDRIIDENCNLTELDTILFMKQICEGIRYMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFSTDMWSVGVITYMLLSGLSPFLGDNDAETLTNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHSRLSAQKNCNSGVLNLTTK", "length": 386 }, "evidence": [ { "id": "RGD:6494757", "url": "https://alliancegenome.org/gene/RGD:6494757#orthology", "database": "AGR" }, { "id": "RGD:1565323", "url": "https://alliancegenome.org/gene/RGD:1565323#orthology", "database": "AGR" }, { "id": "HGNC:27972", "url": "https://alliancegenome.org/gene/HGNC:27972#orthology", "database": "AGR" }, { "id": "MGI:3643758", "url": "https://alliancegenome.org/gene/MGI:3643758#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-128", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-128#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86YV6-1", "protein_name": "Myosin light chain kinase family member 4", "gene_name": "MYLK4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKVKRLEEFNTCYNSNQLEKMAFFQCREEVEKVKCFLEKNSGDQDSRSGHNEAKEVWSNADLTERMPVKSKRTSALAVDIPAPPAPFDHRIVTAKQGAVNSFYTVSKTEILGGGRFGQVHKCEETATGLKLAAKIIKTRGMKDKEEVKNEISVMNQLDHANLIQLYDAFESKNDIVLVMEYVDGGELFDRIIDESYNLTELDTILFMKQICEGIRHMHQMYILHLDLKPENILCVNRDAKQIKIIDFGLARRYKPREKLKVNFGTPEFLAPEVVNYDFVSFPTDMWSVGVIAYMLLSGLSPFLGDNDAETLNNILACRWDLEDEEFQDISEEAKEFISKLLIKEKSWRISASEALKHPWLSDHKLHSRLNAQKKKNRGSDAQDFVTK", "length": 388 }, "evidence": [ { "id": "RGD:6494757", "url": "https://alliancegenome.org/gene/RGD:6494757#orthology", "database": "AGR" }, { "id": "RGD:1565323", "url": "https://alliancegenome.org/gene/RGD:1565323#orthology", "database": "AGR" }, { "id": "HGNC:27972", "url": "https://alliancegenome.org/gene/HGNC:27972#orthology", "database": "AGR" }, { "id": "MGI:3643758", "url": "https://alliancegenome.org/gene/MGI:3643758#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041001-128", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041001-128#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein serine/threonine kinase activity", "id": "GO:0004674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004674", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4" } ], "pmid": "" }, { "name": "myosin light chain kinase activity", "id": "GO:0004687", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004687", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPX4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 619, "end_pos": 621, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PPX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPX4" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 416, "end_pos": 671, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 619, "end_pos": 621 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PLH2-1", "uniprot_ac": "A0A8M9PLH2", "uniprot_id": "A0A8M9PLH2_DANRE", "mass": { "chemical_mass": 65940.0, "monoisotopic_mass": 65940.0 }, "refseq": { "ac": "XP_021325744", "name": "mucolipin-3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325744" }, "gene_names": [ { "name": "mcoln3b", "type": "recommended", "evidence": [ { "id": "A0A8M9PLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2" } ] }, { "name": "mcoln3b", "type": "synonym", "evidence": [ { "id": "XP_021325744", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325744" } ] } ], "protein_names": [ { "name": "Mucolipin-3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PLH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2/entry#names_and_taxonomy" } ] }, { "name": "mucolipin-3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325744", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325744" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325744", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325744" } ] } ], "disease": [ { "disease_id": "DOID:0080490", "recommended_name": { "id": "DOID:0080490", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080490", "name": "mucolipidosis type IV", "description": "A mucolipidosis that is characterized by delayed development and vision impairment that worsens over time." }, "synonyms": [ { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "mucolipidosis type IV", "description": "A lysosomal disease characterized by psychomotor delay, progressive visual impairment, and achlorhydria." }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "ML 4", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "ML IV", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "ML4", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "MLIV", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "Mucolipidosis IV", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "mucolipidosis IV", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "mucolipidosis type 4", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "mucolipidosis type IV", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "sialolipidosis", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "Berman syndrome", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "ganglioside neuraminidase deficiency", "description": "" }, { "id": "MONDO:0009653", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009653", "name": "ganglioside sialidase deficiency", "description": "" }, { "id": "MIM:252650", "resource": "MIM", "url": "https://www.omim.org/entry/252650", "name": "Mucolipidosis 4", "description": "Mucolipidosis 4" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080490", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080490" } ] }, { "disease_id": "DOID:3343", "recommended_name": { "id": "DOID:3343", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3343", "name": "glycoproteinosis", "description": "A mucolipidosis that is characterized by a deficiency of the enzyme alpha-N -acetyl neuraminidase (sialidase)." }, "synonyms": [ { "id": "DOID:3343", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3343", "name": "Mucolipidosis type I", "description": "" }, { "id": "DOID:3343", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3343", "name": "sialidosis", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis type 2", "description": "A rare lysosomal storage disease, and the severe, early onset form of sialidosis characterized by a progressively severe mucopolysaccharidosis-like phenotype (coarse facies, dysostosis multiplex, hepatosplenomegaly), macular cherry-red spots as well as psychomotor and developmental delay. ST-2 displays a broad spectrum of clinical severity with antenatal/congenital, infantile and juvenile presentations." }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "NEU1 sialidosis", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "dysmorphic sialidosis", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "dysmorphic sialidosis with renal involvement", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "infantile dysmorphic sialidosis", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "mucolipidosis I", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "nephrosialidosis", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis caused by mutation in NEU1", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis type II", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis, type 2", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis, type I", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "ML1", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "NEU 1 deficiency", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "mucolipidosis type 1", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis, type II", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis type 2", "description": "A rare lysosomal storage disease, and the severe, early onset form of sialidosis characterized by a progressively severe mucopolysaccharidosis-like phenotype (coarse facies, dysostosis multiplex, hepatosplenomegaly), macular cherry-red spots as well as psychomotor and developmental delay. ST-2 displays a broad spectrum of clinical severity with antenatal/congenital, infantile and juvenile presentations." }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "NEU1 sialidosis", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "dysmorphic sialidosis", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "dysmorphic sialidosis with renal involvement", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "infantile dysmorphic sialidosis", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "mucolipidosis I", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "nephrosialidosis", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis caused by mutation in NEU1", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis type II", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis, type 2", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis, type I", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "ML1", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "NEU 1 deficiency", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "mucolipidosis type 1", "description": "" }, { "id": "MONDO:0009738", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009738", "name": "sialidosis, type II", "description": "" }, { "id": "MIM:256550", "resource": "MIM", "url": "https://www.omim.org/entry/256550", "name": "Sialidosis", "description": "Sialidosis" } ], "unlinked_id_list": [], "evidence": [ { "id": "3343", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3343" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLH2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mcoln3b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080225-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080225-25", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PLH2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PLH2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100001113", "url": "https://www.ncbi.nlm.nih.gov/gene/100001113", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049134", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049134", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100001113", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001113", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PLH2", "url": "https://www.orthodb.org/?gene=A0A8M9PLH2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12127:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12127:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08016", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08016", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21381", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21381", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325744", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325744", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "29671", "url": "https://www.rhea-db.org/rhea/29671", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9P5Q1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P5Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P5Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLH2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PTT0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PTT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PTT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMY6", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMY6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMY7", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMY7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IN12", "url": "https://www.uniprot.org/uniprotkb/A0AC58IN12", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IN12-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IN12-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080225-25", "url": "https://zfin.org/ZDB-GENE-080225-25", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDDSREDYLCINDPNGNWSECEAHVDPALEAFRRKLKYFFMNPCDKYKARQRKPWKLFLQIVKIAVVTVQLVSFGLSNQMVVQFKEENLLTFRHLFLKNYSESNTNTYAIYTQLDVYTHITHIVQQFLMLPSITVGNHEYEQEGDVYTPLCICQQFYHNGSISPANETFDIDSRVDQECSLIYPQDPFTESPLNFTLHFERLLSVTVNFTLKAINLETVEYHELPDCYVFNIMIQFDNKAHSGRILVDLDNEVHIYECSDWSMTGASARNMYMMVLFDAVVILILSTSLLLCIRSVKAGVLLQKEYSEFSLRRYRKCVSLSERLEFINGWYLLIIVSDVLTISGSVLKIVIQLKAVASYDLCSILLGTGTMLVWIGVLRYMGYLKKYNSMLCVCCVVQILIITLRVALPNVIRFTCCAAMIYLGYCFCGWIVLGPYHTKFRTLNTVSESLFSLINGDDMFATFKNMQQKSFVVWLFSRLYLYTFVSLFIYMVLSLFITLITDTYDTIKHQQLDGEPVSDLQAFVLQCKDLPDSGEFSVEKTNSISSTGGGKLMCCCSHRSSDSDEDTHFSECSS", "length": 574, "header": "tr|A0A8M9PLH2-1|A0A8M9PLH2_DANRE Isoform 1 of Mucolipin-3 isoform X1 OS=Danio rerio OX=7955 GN=mcoln3b PE=4 SV=1 CANONICAL=A0A8M9PLH2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9P5Q1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2/entry#A0A8M9P5Q1-1", "sequence": { "sequence": "MDDSREDYLCINDPNGNWSECEAHVDPALEAFRRKLKYFFMNPCDKYKARQRKPWKLFLQIVKIAVVTVQLVSFGLSNQMVVQFKEENLLTFRHLFLKNYSESNTNTYAIYTQLDVYTHITHIVQQFLMLPSITVGNHEYEQEGDVYTPLCICQQFYHNGSISPANETFDIDSRVDQECSLIYPQDPFTESPLNFTLHFERLLSVTVNFTLKAINLETVEYHELPDCYVFNIMIQFDNKAHSGRILVDLDNEVHIYECSDWSMTGASRNMYMMVLFDAVVILILSTSLLLCIRSVKAGVLLQKEYSEFSLRRYRKCVSLSERLEFINGWYLLIIVSDVLTISGSVLKIVIQLKAVASYDLCSILLGTGTMLVWIGVLRYMGYLKKYNILIITLRVALPNVIRFTCCAAMIYLGYCFCGWIVLGPYHTKFRTLNTVSESLFSLINGDDMFATFKNMQQKSFVVWLFSRLYLYTFVSLFIYMVLSLFITLITDTYDTIKHQQLDGEPVSDLQAFVLQCKDLPDSGEFSVEKTNSISSTGGGKLMCCCSHRSSDSDEDTHFSECSS", "length": 563, "header": "tr|A0A8M9P5Q1-1|A0A8M9PLH2_DANRE Computationally mapped isoform of Mucolipin-3 isoform X1 OS=Danio rerio OX=7955 GN=mcoln3b PE=4 SV=1 CANONICAL=A0A8M9PLH2-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PLH2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2/entry#A0A8M9PLH2-1", "sequence": { "sequence": "MDDSREDYLCINDPNGNWSECEAHVDPALEAFRRKLKYFFMNPCDKYKARQRKPWKLFLQIVKIAVVTVQLVSFGLSNQMVVQFKEENLLTFRHLFLKNYSESNTNTYAIYTQLDVYTHITHIVQQFLMLPSITVGNHEYEQEGDVYTPLCICQQFYHNGSISPANETFDIDSRVDQECSLIYPQDPFTESPLNFTLHFERLLSVTVNFTLKAINLETVEYHELPDCYVFNIMIQFDNKAHSGRILVDLDNEVHIYECSDWSMTGASARNMYMMVLFDAVVILILSTSLLLCIRSVKAGVLLQKEYSEFSLRRYRKCVSLSERLEFINGWYLLIIVSDVLTISGSVLKIVIQLKAVASYDLCSILLGTGTMLVWIGVLRYMGYLKKYNSMLCVCCVVQILIITLRVALPNVIRFTCCAAMIYLGYCFCGWIVLGPYHTKFRTLNTVSESLFSLINGDDMFATFKNMQQKSFVVWLFSRLYLYTFVSLFIYMVLSLFITLITDTYDTIKHQQLDGEPVSDLQAFVLQCKDLPDSGEFSVEKTNSISSTGGGKLMCCCSHRSSDSDEDTHFSECSS", "length": 574, "header": "tr|A0A8M9PLH2-1|A0A8M9PLH2_DANRE Isoform 1 of Mucolipin-3 isoform X1 OS=Danio rerio OX=7955 GN=mcoln3b PE=4 SV=1 CANONICAL=A0A8M9PLH2-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PTT0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2/entry#A0A8M9PTT0-1", "sequence": { "sequence": "MDDSREDYLCINDPNGNWSECEAHVDPALEAFRRKLKYFFMNPCDKYKARQRKPWKLFLQIVKIAVVTVQLVSFGLSNQMVVQFKEENLLTFRHLFLKNYSESNTNTYAIYTQLDVYTHITHIVQQFLMLPSITVGNHEYEQEGDVYTPLCICQQFYHNGSISPANETFDIDSRVDQECSLIYPQDPFTESPLNFTLHFERLLSVTVNFTLKAINLETVEYHELPDCYVFNIMIQFDNKAHSGRILVDLDNEVHIYECSDWSMTGASARNMYMMVLFDAVVILILSTSLLLCIRSVKAGVLLQKEYSEFSLRRYRKCVSLSERLEFINGWYLLIIVSDVLTISGSVLKIVIQLKAVASYDLCSILLGTGTMLVWIGVLRYMGYLKKYNILIITLRVALPNVIRFTCCAAMIYLGYCFCGWIVLGPYHTKFRTLNTVSESLFSLINGDDMFATFKNMQQKSFVVWLFSRLYLYTFVSLFIYMVLSLFITLITDTYDTIKHQQLDGEPVSDLQAFVLQCKDLPDSGEFSVEKTNSISSTGGGKLMCCCSHRSSDSDEDTHFSECSS", "length": 564, "header": "tr|A0A8M9PTT0-1|A0A8M9PLH2_DANRE Computationally mapped isoform of Mucolipin-3 isoform X1 OS=Danio rerio OX=7955 GN=mcoln3b PE=4 SV=1 CANONICAL=A0A8M9PLH2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IMY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2/entry#A0AC58IMY6-1", "sequence": { "sequence": "MDDSREDYLCINDPNGNWSECEAHVDPALEAFRRKLKYFFMNPCDKYKARQRKPWKLFLQIVKIAVVTVQLVSFGLSNQMVVQFKEENLLTFRHLFLKNYSESNTNTYAIYTQLDVYTHITHIVQQFLMLPSITVGNHEYEQEGDVYTPLCICQQFYHNGSISPANETFDIDSRVDQECSLIYPQDPFTESPLNFTLHFERLLSVTVNFTLKAINLETVEYHELPDCYVFNIMIQFDNKAHSGRILVDLDNEVHIYECSDWSMTGASARNMYMMVLFDAVVILILSTSLLLCIRSVKAGVLLQKEYSEFSLRRYRKCVSLSERLEFINGWYLLIIVSDVLTISGSVLKIVIQLKAVASYDLCSILLGTGTMLVWIGVLRYMGYLKKYNVRLLFLLLSNTNIHSAATLLASHSCCRFVGCTSMMPISRSTTSQSCSIGLSSGDCGGHLSTVNSSSCSRNQSEMTCCVILLEVAIRRWRHCAHKGMDMVSSNTQVGCGVDAQLVLMDPKKISPTPLHHHHQPEPLTQGRMIHAFMLLRPNCEPSI", "length": 543, "header": "tr|A0AC58IMY6-1|A0AC58IMY6_DANRE Computationally mapped isoform of Mucolipin-3 isoform X5 OS=Danio rerio OX=7955 GN=mcoln3b PE=4 SV=1 CANONICAL=A0A8M9PLH2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IMY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2/entry#A0AC58IMY7-1", "sequence": { "sequence": "MDDSREDYLCINDPNGNWSECEAHVDPALEAFRRKLKYFFMNPCDKYKARQRKPWKLFLQIVKIAVVTVQLVSFGLSNQMVVQFKEENLLTFRHLFLKNYSESNTNTYAIYTQLDVYTHITHIVQQFLMLPSITVGNHEYEQEGDVYTPLCICQQFYHNGSISPANETFDIDSRVDQECSLIYPQDPFTESPLNFTLHFERLLSVTVNFTLKAINLETVEYHELPDCYVFNIMIQFDNKAHSGRILVDLDNEVHIYECSDWSMTGASRNMYMMVLFDAVVILILSTSLLLCIRSVKAGVLLQKEYSEFSLRRYRKCVSLSERLEFINGWYLLIIVSDVLTISGSVLKIVIQLKAVASYDLCSILLGTGTMLVWIGVLRYMGYLKKYNVRLLFLLLSNTNIHSAATLLASHSCCRFVGCTSMMPISRSTTSQSCSIGLSSGDCGGHLSTVNSSSCSRNQSEMTCCVILLEVAIRRWRHCAHKGMDMVSSNTQVGCGVDAQLVLMDPKKISPTPLHHHHQPEPLTQGRMIHAFMLLRPNCEPSI", "length": 542, "header": "tr|A0AC58IMY7-1|A0AC58IMY7_DANRE Computationally mapped isoform of Mucolipin-3 isoform X6 OS=Danio rerio OX=7955 GN=mcoln3b PE=4 SV=1 CANONICAL=A0A8M9PLH2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IN12-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2/entry#A0AC58IN12-1", "sequence": { "sequence": "MDDSREDYLCINDPNGNWSECEAHVDPALEAFRRKLKYFFMNPCDKYKARQRKPWKLFLQIVKIAVVTVQLVSFGLSNQMVVQFKEENLLTFRHLFLKNYSESNTNTYAIYTQLDVYTHITHIVQQFLMLPSITVGNHEYEQEGDVYTPLCICQQFYHNGSISPANETFDIDSRVDQECSLIYPQDPFTESPLNFTLHFERLLSVTVNFTLKAINLETVEYHELPDCYVFNIMIQFDNKAHSGRILVDLDNEVHIYECSDWSMTGASRNMYMMVLFDAVVILILSTSLLLCIRSVKAGVLLQKEYSEFSLRRYRKCVSLSERLEFINGWYLLIIVSDVLTISGSVLKIVIQLKAVASYDLCSILLGTGTMLVWIGVLRYMGYLKKYNSMLCVCCVVQILIITLRVALPNVIRFTCCAAMIYLGYCFCGWIVLGPYHTKFRTLNTVSESLFSLINGDDMFATFKNMQQKSFVVWLFSRLYLYTFVSLFIYMVLSLFITLITDTYDTIKHQQLDGEPVSDLQAFVLQCKDLPDSGEFSVEKTNSISSTGGGKLMCCCSHRSSDSDEDTHFSECSS", "length": 573, "header": "tr|A0AC58IN12-1|A0AC58IN12_DANRE Computationally mapped isoform of Mucolipin-3 isoform X2 OS=Danio rerio OX=7955 GN=mcoln3b PE=4 SV=1 CANONICAL=A0A8M9PLH2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100001113", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001113", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZXW7-1", "protein_name": "Mucolipin TRP cation channel 3", "gene_name": "Mcoln3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPYSRISLRNSLDGGFLLSDDSSLCPVDLKLPSTPIGPLKTMLLVDREMANPEVVVSSCSSHQDESPCTFYPSSSQSEQLLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQNDVYDQIIFAVTRYLQLRNISVGNHAYENKGTKQSAMAVCQHFYRQGTICPGNDTFDIDPEVETDCFLIEPEEAFHMGTPGENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLSSLVLCARSVIRGLQLQQEFVNFFLLHYKKEVSASDQMEFINGWYIMIIVSDILTIVGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHEKFRSLNKVSECLFSLINGDDMFSTFAKMQQKSYLVWLFSRVYLYSFISLFIYMILSLFIALITDTYETIKHYQQDGFPETELRKFIAECKDLPNSGKYRLEDDPPGSLFCCCKK", "length": 601 }, "evidence": [ { "id": "HGNC:13358", "url": "https://alliancegenome.org/gene/HGNC:13358#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080225-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080225-25#orthology", "database": "AGR" }, { "id": "RGD:1308420", "url": "https://alliancegenome.org/gene/RGD:1308420#orthology", "database": "AGR" }, { "id": "MGI:1890500", "url": "https://alliancegenome.org/gene/MGI:1890500#orthology", "database": "AGR" }, { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G3L4-1", "protein_name": "Mucolipin TRP cation channel 1", "gene_name": "Mcoln1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMLPRTWAVETEQLLTPNPGYGTQAGTSPAPTTPPEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLVVTFREENTIAFRHLFLLGYSDGSDDTFAAYTREQLYQAIFYAVDQYLTLPEISLGRYAYVRGGGGPWANGSALALCQRYYHRGHVDPANDTFDIDPRVVTDCIQVDPPDRPPDIPSEDLDFLDGSTSYKNITLKFHKLINVTIHFQLKTINLQSLINNEIPDCYTFSILITFDNKAHSGRIPIRLETQTHIQECKHPSVSRHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVVFMWRRRGREISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLVWVGVIRYLTFFHKYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGTGTEKSELQAYIEQCQDSPTSGKFRRGSGSTCSLLCCCGRNSPEDHSLLVN", "length": 579 }, "evidence": [ { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9P7U6-1", "protein_name": "Mucolipin-3 isoform X1", "gene_name": "mcoln3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDRASHTHESATLLDPECVESLRRKLKYFFMSPCQKYSTRGRIPWKMMLQILKIVIITVQLVSFGLSNEMMVTFKEENLIAFKHFFLKNYKDSNKHYALYTKHEVHDHILYTIRRYLQLQNLTIGNQALEMIDGLATPLSLCQQLYRHARVVPSNETFEIDPHVETECVSVYPLSPITTDSLENSLNLTLDFQRLLAVNIYLKIKAINIQTVRHQELPDCYDFSINIMFDNRAHSGQIKISLSSGVQINVCKDWNISGSTDSHFALIVVFDCLIICFCLLSLILCTRSVHTGFLLQTEYRRFMSSQHSKSVSWSERLEFINGWYILIIISDALTIAGSILKICIQSKELTSYDVCSILLGTATMLVWIGVMRYLSFFQKYYILILTLKAALPNVIRFSICAVMIYLSYCFCGWIVLGPHHENFRTFSRVAGCLFSMINGDEIYSTFTKLREYSTLVWLFSRLYVYSFIPVFTYMVLSVFIALITDTYETIRHYQKHGAPLSELQAFIADCRDPRNYDKNTTNEDEESSSFCCLCAPCVFCT", "length": 542 }, "evidence": [ { "id": "HGNC:13358", "url": "https://alliancegenome.org/gene/HGNC:13358#orthology", "database": "AGR" }, { "id": "RGD:1308420", "url": "https://alliancegenome.org/gene/RGD:1308420#orthology", "database": "AGR" }, { "id": "MGI:1890500", "url": "https://alliancegenome.org/gene/MGI:1890500#orthology", "database": "AGR" }, { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8IZK6-1", "protein_name": "Mucolipin-2", "gene_name": "MCOLN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARQPYRFPQARIPERGSGVFRLTVRNAMAHRDSEMKEECLREDLKFYFMSPCEKYRARRQIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGYSGTDEDDYSCSVYTQEDAYESIFFAINQYHQLKDITLGTLGYGENEDNRIGLKVCKQHYKKGTMFPSNETLNIDNDVELDCVQLDLQDLSKKPPDWKNSSFFRLEFYRLLQVEISFHLKGIDLQTIHSRELPDCYVFQNTIIFDNKAHSGKIKIYFDSDAKIEECKDLNIFGSTQKNAQYVLVFDAFVIVICLASLILCTRSIVLALRLRKRFLNFFLEKYKRPVCDTDQWEFINGWYVLVIISDLMTIIGSILKMEIKAKNLTNYDLCSIFLGTSTLLVWVGVIRYLGYFQAYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHDKFENLNTVAECLFSLVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMILSLFIALITDSYDTIKKFQQNGFPETDLQEFLKECSSKEEYQKESSAFLSCICCRRRKRSDDHLIPIS", "length": 566 }, "evidence": [ { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K595-1", "protein_name": "Mucolipin-2", "gene_name": "Mcoln2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGDEETLDLPAWNRVPDLTWGPHHRSAMASLDSEVREECLREDLKFYFMSPCEKYRARRQIPWKLGLQILKIVMVTTQLVRFGLSNQLVVAFKEDNTVAFKHLFLKGFSGVDEDDYSCSIYTQENTYESIFFAIKQYRHLKNISLATLGYGESEDNRTGLKVCKQHYKTGAMFSSNETLNIDSDIETDCIHLDLQVLTTEPEDWAQTSFFRLDFYRLVQVDISFALKGIDLQAVHSREIPDCYLFQNTITFDNTAHSGKIKIYLNSEANIEECKNMNISGSTQRSTHYLLVFDVFVIMICLASLILCTRSIVLALRLRKRFLNFFLEKYKQRVCGADQWEFVNGWYVLVTISDLMTIIGSILKMEIKAKKLTNYDVCSILLGTSTLFVWVGVIRYLGYFQTYNVLILTMQASLPKVLRFCACAGMIYLGYTFCGWIVLGPYHEKFENLNIVAECLFSLVNGDDMFATFAQIQQKSILVWLFSRLYLYSFISLFIYMVLSLFIALITDSYHTIKKYQQHGFPETDLQKFLKESGSKDGYQKQPSALLSCLCCLRRRRSNDHLILID", "length": 566 }, "evidence": [ { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4F0-1", "protein_name": "Mucolipin-3", "gene_name": "Mcoln3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANPEVLVSSCRARQDESPCTFHPSSSPSEQLLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQSEVYDQIIFAVTQYLQLQNISVGNHAYENKGTKQSAMAICQHFYRQGTICPGNDTFDIDPEVETECFLVEPDEASHLGTPGENKLNLSLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIKECKDWHVSGSIQKNTHYMMIFDAFVILTCLASLVLCARSVIRGLQLQQEFVNFFLLHYKKEVSASDQMEFINGWYIMIIISDILTIVGSVLKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVMRFCCCAAMIYLGYCFCGWIVLGPYHEKFRSLNRVSECLFSLINGDDMFSTFAKMQQKSYLVWLFSRVYLYSFISLFIYMILSLFIALITDTYETIKHYQQDGFPETELRKFIAECKDLPNSGKYRLEDDPPGSLLCCCKK", "length": 553 }, "evidence": [ { "id": "HGNC:13358", "url": "https://alliancegenome.org/gene/HGNC:13358#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080225-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080225-25#orthology", "database": "AGR" }, { "id": "RGD:1308420", "url": "https://alliancegenome.org/gene/RGD:1308420#orthology", "database": "AGR" }, { "id": "MGI:1890500", "url": "https://alliancegenome.org/gene/MGI:1890500#orthology", "database": "AGR" }, { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TDD5-1", "protein_name": "Mucolipin-3", "gene_name": "MCOLN3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADPEVVVSSCSSHEEENRCNFNQQTSPSEELLLEDQMRRKLKFFFMNPCEKFWARGRKPWKLAIQILKIAMVTIQLVLFGLSNQMVVAFKEENTIAFKHLFLKGYMDRMDDTYAVYTQSDVYDQLIFAVNQYLQLYNVSVGNHAYENKGTKQSAMAICQHFYKRGNIYPGNDTFDIDPEIETECFFVEPDEPFHIGTPAENKLNLTLDFHRLLTVELQFKLKAINLQTVRHQELPDCYDFTLTITFDNKAHSGRIKISLDNDISIRECKDWHVSGSIQKNTHYMMIFDAFVILTCLVSLILCIRSVIRGLQLQQEFVNFFLLHYKKEVSVSDQMEFVNGWYIMIIISDILTIIGSILKMEIQAKSLTSYDVCSILLGTSTMLVWLGVIRYLGFFAKYNLLILTLQAALPNVIRFCCCAAMIYLGYCFCGWIVLGPYHDKFRSLNMVSECLFSLINGDDMFATFAKMQQKSYLVWLFSRIYLYSFISLFIYMILSLFIALITDTYETIKQYQQDGFPETELRTFISECKDLPNSGKYRLEDDPPVSLFCCCKK", "length": 553 }, "evidence": [ { "id": "HGNC:13358", "url": "https://alliancegenome.org/gene/HGNC:13358#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080225-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080225-25#orthology", "database": "AGR" }, { "id": "RGD:1308420", "url": "https://alliancegenome.org/gene/RGD:1308420#orthology", "database": "AGR" }, { "id": "MGI:1890500", "url": "https://alliancegenome.org/gene/MGI:1890500#orthology", "database": "AGR" }, { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99J21-1", "protein_name": "Mucolipin-1", "gene_name": "Mcoln1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATPAGRRASETERLLTPNPGYGTQVGTSPAPTTPTEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLVVTFREENTIAFRHLFLLGYSDGSDDTFAAYTQEQLYQAIFYAVDQYLILPEISLGRYAYVRGGGGPWANGSALALCQRYYHRGHVDPANDTFDIDPRVVTDCIQVDPPDRPPDIPSEDLDFLDGSASYKNLTLKFHKLINVTIHFQLKTINLQSLINNEIPDCYTFSILITFDNKAHSGRIPIRLETKTHIQECKHPSVSRHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVVFMWRRRGREISLWERLEFVNGWYILLVTSDVLTISGTVMKIGIEAKNLASYDVCSILLGTSTLLVWVGVIRYLTFFHKYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGHSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGTGTEKSELQAYIEQCQDSPTSGKFRRGSGSACSLFCCCGRDSPEDHSLLVN", "length": 580 }, "evidence": [ { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9GZU1-1", "protein_name": "Mucolipin-1", "gene_name": "MCOLN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAPAGPRGSETERLLTPNPGYGTQAGPSPAPPTPPEEEDLRRRLKYFFMSPCDKFRAKGRKPCKLMLQVVKILVVTVQLILFGLSNQLAVTFREENTIAFRHLFLLGYSDGADDTFAAYTREQLYQAIFHAVDQYLALPDVSLGRYAYVRGGGDPWTNGSGLALCQRYYHRGHVDPANDTFDIDPMVVTDCIQVDPPERPPPPPSDDLTLLESSSSYKNLTLKFHKLVNVTIHFRLKTINLQSLINNEIPDCYTFSVLITFDNKAHSGRIPISLETQAHIQECKHPSVFQHGDNSFRLLFDVVVILTCSLSFLLCARSLLRGFLLQNEFVGFMWRQRGRVISLWERLEFVNGWYILLVTSDVLTISGTIMKIGIEAKNLASYDVCSILLGTSTLLVWVGVIRYLTFFHNYNILIATLRVALPSVMRFCCCVAVIYLGYCFCGWIVLGPYHVKFRSLSMVSECLFSLINGDDMFVTFAAMQAQQGRSSLVWLFSQLYLYSFISLFIYMVLSLFIALITGAYDTIKHPGGAGAEESELQAYIAQCQDSPTSGKFRRGSGSACSLLCCCGRDPSEEHSLLVN", "length": 580 }, "evidence": [ { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VW35-1", "protein_name": "Transient receptor potential cation channel, mucolipin", "gene_name": "Trpml", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQSYGPGAQTAPAVKRRTDSYEAAQQQQQSPESDEEYVNTRILRRQVQLQSTPVAPVVPMPISAGSGTAPPSVDGREEQPEFPGSSAASYQEERMRRKLQFFFMNPIEKWQAKRKFPYKFVVQIVKIFLVTMQLCLFAHSRYNHINYTGDNRFAFSHLFLRGWDSSREVESYPPAVGPFALYLKSEFFDTVQYAVNGYANVSRSIGPYDYPTPNNTMPPLKLCLQNYREGTIFGFNESYIFDPHIDEVCERLPPNVTTIGVENYLRQRDVEVNFASLVSAQLTFKIKTVNFKANGGPLSAPDCFRFDISITFNNRDHDGQMLLSLDAEATRLKCHGATDFISDANFDSMLRSVLNIFVLLTCALSFALCTRALWRAYLLRCTTVNFFRSQFGKELSFDGRLEFVNFWYIMIIFNDVLLIIGSALKEQIEGRYLVVDQWDTCSLFLGIGNLLVWFGVLRYLGFFKTYNVVILTLKKAAPKILRFLIAALLIYAGFVFCGWLILGPYHMKFRSLATTSECLFALINGDDMFATFATLSSKATWLWWFCQIYLYSFISLYIYVVLSLFIAVIMDAYDTIKAYYKDGFPTTDLKAFVGTRTAEDISSGVFMTDLDDFDQTSFLDVVKSICCCGRCGRHQEPAQPNSGYTSLSSIMK", "length": 652 }, "evidence": [ { "id": "HGNC:13358", "url": "https://alliancegenome.org/gene/HGNC:13358#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080225-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080225-25#orthology", "database": "AGR" }, { "id": "RGD:1308420", "url": "https://alliancegenome.org/gene/RGD:1308420#orthology", "database": "AGR" }, { "id": "MGI:1890500", "url": "https://alliancegenome.org/gene/MGI:1890500#orthology", "database": "AGR" }, { "id": "FB:FBgn0261361", "url": "https://alliancegenome.org/gene/FB:FBgn0261361#orthology", "database": "AGR" }, { "id": "FB:FBgn0262516", "url": "https://alliancegenome.org/gene/FB:FBgn0262516#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLH2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2" } ], "pmid": "" }, { "name": "endosome membrane", "id": "GO:0010008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010008", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLH2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2" } ], "pmid": "" }, { "name": "lysosomal membrane", "id": "GO:0005765", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005765", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLH2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "monoatomic cation channel activity", "id": "GO:0005261", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005261", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLH2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2" } ], "pmid": "" }, { "name": "NAADP-sensitive calcium-release channel activity", "id": "GO:0072345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072345", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLH2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 17, "end_pos": 19, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "29671", "name": "", "equation": "Ca(2+)(in) = Ca(2+)(out)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8M9Q2T2-1", "A0AC58II33-1", "A0AC58HSD6-1" ], "evidence": [ { "id": "29671", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/29671" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8M9Q2T2", "gene_name": "trpm6", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0A8M9Q2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2T2" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0A8M9Q2T2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2T2" } ] } ] }, { "uniprot_ac": "A0AC58HSD6", "gene_name": "trpm7", "activity": [ { "ec_number": "2.7.11.1", "activity": "L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+).", "evidence": [ { "id": "A0AC58HSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HSD6" } ] }, { "ec_number": "2.7.11.1", "activity": "", "evidence": [ { "id": "A0AC58HSD6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58HSD6" } ] } ] }, { "uniprot_ac": 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"database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLH2" }, { "id": "PF08016", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Polycystin cation channel PKD1/PKD2", "eco_id": "ECO_0000259", "start_pos": 392, "end_pos": 507, "start_aa": "Cys", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 166, "end_pos": 168 }, { "start_pos": 17, "end_pos": 19 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PP74-1", "uniprot_ac": "A0A8M9PP74", "uniprot_id": "A0A8M9PP74_DANRE", "mass": { "chemical_mass": 161382.0, "monoisotopic_mass": 161382.0 }, "refseq": { "ac": "XP_073788286", "name": "uncharacterized protein si:dkeyp-68b7.12 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073788286" }, "gene_names": [ { "name": "arhgap30", "type": "recommended", "evidence": [ { "id": "A0A8M9PP74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74" } ] }, { "name": "si:dkeyp-68b7.12", "type": "synonym", "evidence": [ { "id": "XP_073788286", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073788286" }, { "id": "A0A8M9PP74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkeyp-68b7.12 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PP74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkeyp-68b7.12 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_073788286", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073788286" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073788286", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073788286" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PP74", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "arhgap30", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-117", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-117", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PP74", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PP74", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100151151", "url": "https://www.ncbi.nlm.nih.gov/gene/100151151", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100151151", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100151151", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EENATCE", "url": "https://omabrowser.org/oma/group/EENATCE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PP74", "url": "https://www.orthodb.org/?gene=A0A8M9PP74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15729", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15729", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15729:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15729:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073788286", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073788286", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PBM9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PBM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PBM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PP74", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PP74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-117", "url": "https://zfin.org/ZDB-GENE-070912-117", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRRGRRKPGGRDKVFGCDLLEHLSSSAQDVPQVLRSCSEFIEKHGIVDGIYRLSGVSSNTQKLRSEFDSEGSPDLYKEVYLQDIHCVSSLCKAYFRELPNPLLTYELYDRFADAVAVQLEDERLVKIREVLKDLPAPHYRTLEFLMRHLVKMSTFASETNMHSRNLAIVWAPNLLRSKDIESTGFNGTAAFMEVRVQSIVVEFVLTHVPELFPETGVSMERRKSLPSPSILSSQDDHFFKSLPLISSGNLSPGDGPLPMRPYHAIIDGTDKRKGSLKGRKWKSIFNLGARLHDPRKKNKYCPKDKEKTSLRPAKSMDSLSTGTTALEDSKPPQAALPPLVLSSASGSSEGVASSGVGVASAGGGVSSGYAVTYRRTGGAQVSVVSAGIPGSYTRLDSAGGAEGPAQGVAKSPAISSKAERRAGMHITGPFSVTVPLHITSGLALGVLHGGWNDKEQTQDEDVKSTDGDSQSKNCDQNEANSSVETQVDCGKDVIETEGKSTDGNKAETEDLNSTQESVKDNVEDVKGKEETTEEEYMDMRAHVQQTPVSPIYCEFQEQELDLQEAFGFLDSMDNSVSNQPEFSVEAPCFEGEYEEDEDEDQAVLSPAQNCSENCEKPKSSSPSFTHRPLPGKSHSLPYKSRPFLPALSLSSDDDYSPADDEDDDDDDDEDESDKGSEYEDMFCKSLPSCRDFHSLSWAGPQTPSSKSERSDEIAQSVGQSEDRIPIALSLKDDSKTESLMTNESRNSVDVENNKHVLRREEESAESEEDTYFGPDSIPSSPEPEKNHISVHEDINRNSASEEQTQIKTQRETDEPESSVKTTLQDDEEQNKTENNEDLESAHDQNNTERQEDLEEDAKDDDKGEQKQEKTAQSEDLQQNNEENAEDEEREEKHEAEMNDVEQNNEGNADDEEKRLKDMSEINDTEQNNEENAGEIQKQMTDMDNLGQNKEGNQENVMEINNIEQNNALEMQNLKLNVEENAKCEKEETQVTQMNDIEQNNEENAEEKQSQMSEVQDLWQNNEQIQENVTDSEQNEEENEKEEQKQETEMQDNIGENTEDEMKETELQEIEQNNAETEREEQNQEIQWQDIEQNNEELAENEKKEQKQENKMQDLEQNDAENEGEEQNQETKMQDLEQNNAENEGKEQNQETKMQDLEQNNAENEKKEQKQENKMQDIEQNNAENEGEKQKQETKMQDSNEDNPENEKNKERNQENVTEINDIVQNDEDKELKQETEMQNNEENATCEKEEKQATEMNDTEQNNEENAGEKPKQQTKMHDDNAANAEGHTSSSADVNNITISGEKAGIIQQTHSEEEITIQRRDSPRKIAAGAAHQTRAVPAVPPKPQNSKLTALNLRKRFENRLSQELHHHHHHEEEDEEEEEEERKLEKEEKRCVSLCFDEAVARATVKRSRENTDRLSASRRDAKTD", "length": 1429, "header": "tr|A0A8M9PP74-1|A0A8M9PP74_DANRE Isoform 1 of Uncharacterized protein si:dkeyp-68b7.12 isoform X1 OS=Danio rerio OX=7955 GN=arhgap30 PE=4 SV=2 CANONICAL=A0A8M9PP74-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PBM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74/entry#A0A8M9PBM9-1", "sequence": { "sequence": 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"length": 1423, "header": "tr|A0A8M9PBM9-1|A0A8M9PP74_DANRE Computationally mapped isoform of Uncharacterized protein si:dkeyp-68b7.12 isoform X1 OS=Danio rerio OX=7955 GN=arhgap30 PE=4 SV=2 CANONICAL=A0A8M9PP74-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PP74-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74/entry#A0A8M9PP74-1", "sequence": { "sequence": "MRRGRRKPGGRDKVFGCDLLEHLSSSAQDVPQVLRSCSEFIEKHGIVDGIYRLSGVSSNTQKLRSEFDSEGSPDLYKEVYLQDIHCVSSLCKAYFRELPNPLLTYELYDRFADAVAVQLEDERLVKIREVLKDLPAPHYRTLEFLMRHLVKMSTFASETNMHSRNLAIVWAPNLLRSKDIESTGFNGTAAFMEVRVQSIVVEFVLTHVPELFPETGVSMERRKSLPSPSILSSQDDHFFKSLPLISSGNLSPGDGPLPMRPYHAIIDGTDKRKGSLKGRKWKSIFNLGARLHDPRKKNKYCPKDKEKTSLRPAKSMDSLSTGTTALEDSKPPQAALPPLVLSSASGSSEGVASSGVGVASAGGGVSSGYAVTYRRTGGAQVSVVSAGIPGSYTRLDSAGGAEGPAQGVAKSPAISSKAERRAGMHITGPFSVTVPLHITSGLALGVLHGGWNDKEQTQDEDVKSTDGDSQSKNCDQNEANSSVETQVDCGKDVIETEGKSTDGNKAETEDLNSTQESVKDNVEDVKGKEETTEEEYMDMRAHVQQTPVSPIYCEFQEQELDLQEAFGFLDSMDNSVSNQPEFSVEAPCFEGEYEEDEDEDQAVLSPAQNCSENCEKPKSSSPSFTHRPLPGKSHSLPYKSRPFLPALSLSSDDDYSPADDEDDDDDDDEDESDKGSEYEDMFCKSLPSCRDFHSLSWAGPQTPSSKSERSDEIAQSVGQSEDRIPIALSLKDDSKTESLMTNESRNSVDVENNKHVLRREEESAESEEDTYFGPDSIPSSPEPEKNHISVHEDINRNSASEEQTQIKTQRETDEPESSVKTTLQDDEEQNKTENNEDLESAHDQNNTERQEDLEEDAKDDDKGEQKQEKTAQSEDLQQNNEENAEDEEREEKHEAEMNDVEQNNEGNADDEEKRLKDMSEINDTEQNNEENAGEIQKQMTDMDNLGQNKEGNQENVMEINNIEQNNALEMQNLKLNVEENAKCEKEETQVTQMNDIEQNNEENAEEKQSQMSEVQDLWQNNEQIQENVTDSEQNEEENEKEEQKQETEMQDNIGENTEDEMKETELQEIEQNNAETEREEQNQEIQWQDIEQNNEELAENEKKEQKQENKMQDLEQNDAENEGEEQNQETKMQDLEQNNAENEGKEQNQETKMQDLEQNNAENEKKEQKQENKMQDIEQNNAENEGEKQKQETKMQDSNEDNPENEKNKERNQENVTEINDIVQNDEDKELKQETEMQNNEENATCEKEEKQATEMNDTEQNNEENAGEKPKQQTKMHDDNAANAEGHTSSSADVNNITISGEKAGIIQQTHSEEEITIQRRDSPRKIAAGAAHQTRAVPAVPPKPQNSKLTALNLRKRFENRLSQELHHHHHHEEEDEEEEEEERKLEKEEKRCVSLCFDEAVARATVKRSRENTDRLSASRRDAKTD", "length": 1429, "header": "tr|A0A8M9PP74-1|A0A8M9PP74_DANRE Isoform 1 of Uncharacterized protein si:dkeyp-68b7.12 isoform X1 OS=Danio rerio OX=7955 GN=arhgap30 PE=4 SV=2 CANONICAL=A0A8M9PP74-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100151151", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100151151", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PP74", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PP74", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PP74", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1027, "end_pos": 1029, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1215, "end_pos": 1217, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1243, "end_pos": 1245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1257, "end_pos": 1259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1297, "end_pos": 1299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 249, "end_pos": 251, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" }, { "start_pos": 609, "end_pos": 611, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" }, { "start_pos": 830, "end_pos": 832, "annotation": "n_glycosylation_sequon" }, { "start_pos": 845, "end_pos": 847, "annotation": "n_glycosylation_sequon" }, { "start_pos": 922, "end_pos": 924, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PP74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP74" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 212, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1027, "end_pos": 1029 }, { "start_pos": 1215, "end_pos": 1217 }, { "start_pos": 1243, "end_pos": 1245 }, { "start_pos": 1257, "end_pos": 1259 }, { "start_pos": 1297, "end_pos": 1299 }, { "start_pos": 186, "end_pos": 188 }, { "start_pos": 249, "end_pos": 251 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 512, "end_pos": 514 }, { "start_pos": 609, "end_pos": 611 }, { "start_pos": 742, "end_pos": 744 }, { "start_pos": 830, "end_pos": 832 }, { "start_pos": 845, "end_pos": 847 }, { "start_pos": 922, "end_pos": 924 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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[ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PRY7-1", "uniprot_ac": "A0A8M9PRY7", "uniprot_id": "A0A8M9PRY7_DANRE", "mass": { "chemical_mass": 83926.0, "monoisotopic_mass": 83926.0 }, "refseq": { "ac": "XP_021329793", "name": "la-related protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329793" }, "gene_names": [ { "name": "larp4ab", "type": "recommended", "evidence": [ { "id": "A0A8M9PRY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7" } ] }, { "name": "larp4ab", "type": "synonym", "evidence": [ { "id": "XP_021329793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329793" } ] } ], "protein_names": [ { "name": "La-related protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PRY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#names_and_taxonomy" } ] }, { "name": "la-related protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021329793", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329793" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021329793.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329793", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329793" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRY7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "larp4ab", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100729-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100729-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PRY7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PRY7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08035", "url": 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] }, { "id": "IPR058699", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058699", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:568283", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568283", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR22792", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22792", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22792:SF48", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22792:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05383", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05383", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26088", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26088", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021329793", "url": 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}, { "id": "A0AC58JVG4", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVG4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVG4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVG4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVG6", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVG6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVH1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVH1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVH1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVH1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVH8", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVH8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVH8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVI4", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVI4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVK4", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVK4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVK6", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVK6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100729-2", "url": "https://zfin.org/ZDB-GENE-100729-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTSESSGQAQQKAEVEPGSVVRDQEEKTGEKHGGMVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRLPLYSRKNVINAFRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKVPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 764, "header": "tr|A0A8M9PRY7-1|A0A8M9PRY7_DANRE Isoform 1 of La-related protein 4 isoform X1 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=2 CANONICAL=A0A8M9PRY7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PF43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0A8M9PF43-1", "sequence": { "sequence": "MLLFVEVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRLPLYSRKNVINAFRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKVPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 735, "header": "tr|A0A8M9PF43-1|A0A8M9PRY7_DANRE Computationally mapped isoform of La-related protein 4 isoform X1 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=2 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PRY7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0A8M9PRY7-1", "sequence": { "sequence": "MTSESSGQAQQKAEVEPGSVVRDQEEKTGEKHGGMVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRLPLYSRKNVINAFRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKVPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 764, "header": "tr|A0A8M9PRY7-1|A0A8M9PRY7_DANRE Isoform 1 of La-related protein 4 isoform X1 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=2 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PY26-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0A8M9PY26-1", "sequence": { "sequence": "MTSESSGQAQQKAEVEPGSVVRDQEEKTGEKHGGMVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRLPLYSRKNVINAFRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKVPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 763, "header": "tr|A0A8M9PY26-1|A0A8M9PRY7_DANRE Computationally mapped isoform of La-related protein 4 isoform X1 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=2 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q4J9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0A8M9Q4J9-1", "sequence": { "sequence": "MTSESSGQAQQKAEVEPGSVVRDQEEKTGEKHGGMVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKVPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 750, "header": "tr|A0A8M9Q4J9-1|A0A8M9PRY7_DANRE Computationally mapped isoform of La-related protein 4 isoform X1 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=2 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q924-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0A8M9Q924-1", "sequence": { "sequence": "MTSESSGQAQQKAEVEPGSVVRDQEEKTGEKHGGMVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRLPLYSRKNVINAFRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 763, "header": "tr|A0A8M9Q924-1|A0A8M9PRY7_DANRE Computationally mapped isoform of La-related protein 4 isoform X1 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=2 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVG0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0AC58JVG0-1", "sequence": { "sequence": "MTSESSGQAQQKAEVEPGSVVRDQEEKTGEKHGGMVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 749, "header": "tr|A0AC58JVG0-1|A0AC58JVG0_DANRE Computationally mapped isoform of La-related protein 4 isoform X7 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=1 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0AC58JVG1-1", "sequence": { "sequence": "MLLFVEVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRLPLYSRKNVINAFRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 733, "header": "tr|A0AC58JVG1-1|A0AC58JVG1_DANRE Computationally mapped isoform of La-related protein 4 isoform X11 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=1 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVG4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0AC58JVG4-1", "sequence": { "sequence": "MTSESSGQAQQKAEVEPGSVVRDQEEKTGEKHGGMVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 748, "header": "tr|A0AC58JVG4-1|A0AC58JVG4_DANRE Computationally mapped isoform of La-related protein 4 isoform X8 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=1 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVG6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0AC58JVG6-1", "sequence": { "sequence": "MTSESSGQAQQKAEVEPGSVVRDQEEKTGEKHGGMVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRLPLYSRKNVINAFRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 762, "header": "tr|A0AC58JVG6-1|A0AC58JVG6_DANRE Computationally mapped isoform of La-related protein 4 isoform X4 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=1 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVH1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0AC58JVH1-1", "sequence": { "sequence": "MLLFVEVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 719, "header": "tr|A0AC58JVH1-1|A0AC58JVH1_DANRE Computationally mapped isoform of La-related protein 4 isoform X13 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=1 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVH8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0AC58JVH8-1", "sequence": { "sequence": "MTSESSGQAQQKAEVEPGSVVRDQEEKTGEKHGGMVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNR", "length": 388, "header": "tr|A0AC58JVH8-1|A0AC58JVH8_DANRE Computationally mapped isoform of La-related protein 4 isoform X14 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=1 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0AC58JVI4-1", "sequence": { "sequence": "MLLFVEVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRLPLYSRKNVINAFRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKVPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 734, "header": "tr|A0AC58JVI4-1|A0AC58JVI4_DANRE Computationally mapped isoform of La-related protein 4 isoform X10 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=1 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0AC58JVK4-1", "sequence": { "sequence": "MLLFVEVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKVPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 720, "header": "tr|A0AC58JVK4-1|A0AC58JVK4_DANRE Computationally mapped isoform of La-related protein 4 isoform X12 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=1 CANONICAL=A0A8M9PRY7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7/entry#A0AC58JVK6-1", "sequence": { "sequence": "MTSESSGQAQQKAEVEPGSVVRDQEEKTGEKHGGMVTTKGAGLNPNAKVWQEVSAPTSQAPEAATETCHWPQADHVSTEEMEGFKEYSVGYGDSESVPAMETGLINGIESVELAYPLYEPVEGETLEEPPALSEESLKESLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEDVKLLTTDMDLILEVLRASPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKSEKCPQVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGFGADSGVYSSPSQYSSPVYLQQVYQPPQQYPLYSLLPQTWTPSPTPYFETPLAPFPNSTFVNGFGTAGNYKTGTSPISLTRNYPRNRNHVKPRADVGQLTETSSGAGSPQPPCTPSSDSNASTLTPLSEPPTSPRENQHSDLSISSRVRRGSYRGMRRRREDERTRPNAELEVKAPSPKFDLATTNFPPLPGGVSGHLPSVTVQTESVLENRMADVVKGISKVPEASKQEVSQDTGTCQGEAQTTGPSVPALKPPTTKVDPPVASVIHQVKKPVLEVQNAVTLPDAAAAVTVNHVQLISAPKPTCSQSTPSTASTPPLPTSTIVQEPRKLSYAEVCQRPPKDPPPVPVAPPSPTPSPSPTPNQPLRELRANKVDGPASSRCSPWDKLEKGESRTSREQTGYQRGNGSRGSGFKLREQQRRPPQGRRCSPQLGYNRRSGKEQNIPPRSPK", "length": 749, "header": "tr|A0AC58JVK6-1|A0AC58JVK6_DANRE Computationally mapped isoform of La-related protein 4 isoform X6 OS=Danio rerio OX=7955 GN=larp4ab PE=4 SV=1 CANONICAL=A0A8M9PRY7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 346, "start_aa": "Thr", "end_pos": 346, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr346", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 624, "start_aa": "Thr", "end_pos": 624, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr624", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 669, "start_aa": "Thr", "end_pos": 669, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr669", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 675, "start_aa": "Thr", "end_pos": 675, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr675", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:568283", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568283", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A7G2-1", "protein_name": "La ribonucleoprotein 4", "gene_name": "Larp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLFVEVTSKGTGLNPNAKVWQEIPSGNPDGTPVTETSWHETAATSGSHPEGNTELSEEMCKEYEVMYSPSCEPTRNTADIEESADGMILGPEDLSYQLYDVSGESSSTISTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPVEEVKALFKNENCPKVISCEFAHNSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINTFFAKNGYRLMDSSMYTQPIQTPTQYPSPVFMQPVYNPHQQYSVYSIVPQSWSPSPAPYFETPLAPFPNGSFVNGFSSPGSYKTNAAAMNMGRPFQKNRVKPHFRSSSGSEHSTDGSVSLGDGPVSRSSSRIFLSERHNPTVTGHQEQTYLPKDAPILQMEQNGDFGRGRRTLFRGRRRREDDRIPRPQPAATEAKAPAPKFDLLATNFPPLPGSSSRMPDELALENRMSDVVKGVCKEKDNEDLRVSCPVPAEDGQTDCASVPQLSISPSPPCTAEPPALSSTTQQEKDQMEDSAAPKDVLNPVPVPVSSPTTTKPSRANTASPCNSTVNTPIAVAPQEPRKLSYAEVCQKPPKEPSPVLVQPLRELRSNVVSPTRNEENGAPEKPVEKPQEKPETRASKDHSGFRGNTIPRGAAGKIREQRRQFSHRAAPQGVTRRNGKEQYVPPRSPK", "length": 722 }, "evidence": [ { "id": "FB:FBgn0035424", "url": "https://alliancegenome.org/gene/FB:FBgn0035424#orthology", "database": "AGR" }, { "id": "HGNC:24320", "url": "https://alliancegenome.org/gene/HGNC:24320#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100729-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100729-2#orthology", "database": "AGR" }, { "id": "MGI:2443114", "url": "https://alliancegenome.org/gene/MGI:2443114#orthology", "database": "AGR" }, { "id": "RGD:6499275", "url": "https://alliancegenome.org/gene/RGD:6499275#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PU52-1", "protein_name": "La-related protein 4B isoform X1", "gene_name": "larp4b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCCFSKELNPNPVNERTSLLQEAIPESSTTKALRDYAWSVADLADEKPSQNGTVNVALETSCNASSTNLSAGLNLIKEGGSSVQEGMTFWEPPVGDPPINEVTVQKGNTSELGKDGRDYCQMKETVPLDSVKKKIADNARMRAKWFCDGQQSHSTAVSVIAKQEQIKTLQDVQSKSASLPKHATLLQNNCIRKSVNLSDSEQGSSGILITDHSFKKELNFYSICLIDLEDLGSECGYQSMTEADAVRYASAPAVSEKALFGNTSLPQDRTISGSDPSLKKTAAQQTDKCPSEKTLGYSTSLPANLALLNEDLKPFSVQENQKPSSGNESTCCSDTKCTGFPNIAVEDTTDQPSPDLLSQYGQMSSTNAASPQGEPADLLKNPDLYDSNGYKTTDLSSPLQQDINGLPDKVELENKHKICDFTEPMDLIKDTVVSDEAEYSVSCLSNTADKPQFPIMIWDKCVSKKTHTEKVHKETSQALSAVSTSASGMQVEIDVQEGLSYENSSEEIENVKFCSETQVSSVKKENLSKSLSCQKVEVEPRQIGMQEEVIFSPCRFSVLQCEGQTNESDMFKVAGVPHGLNCPSHAESICVDLTCNAEEDKMDMTLTPHVYTCSVFPTNQTKIVSESCDIPNREQNVELKADFTNFESCDVNPSPLPTNETVNFEQLMEVTHKCELDYDSVSFFGSSDAEVYTDTQTVPDCSVDEDLSNSIVLASDTSRKDICNKGQAGNSAGSCLSQVELGSELPGFVEQSMDNEIGESCLQHDEKMHIASENFCEDEPKVLGEIGLCTDDGKTEMSECEPQVLAPTLEILNGLNDANNNNEHLESGCSANCVAHTPFEAPCLFEVSEIASCSSGSSNCMRERAFQYMESSSELLASDTQGSSVTYIQEHGEFQDMREMKGGGVDISIPLVSIARLPLETGEVQLCAIHGHGCNDVNSTTTTACVSQPTTSIGDRDFDPSDSKVIDDEISDDIYVNAAIPLPVEPDQVDIYASTPSYEIYFLNNAQLTVPVQVENPQGLDEIDGEQGMLNMVSDLLGKSELNDEVDTGHCLPAWSKEPHVLFSDNQMEACALVSAWDHAVSEASLTMQNVEQDTESDPNVGLQDFQTSMGFIAPYPYNLLATEGSCVWDWQSAYSGLESSKISDLNPNAKAWANYMPKPEASAPTCPDSQQSWVEAADDPSNCISDGYNNSEDKGNWNEEQQVSTSVELPFAAQPESVYLGSSVIEKGIVSNQNTSMKGVDDSDSSRQLEDLREQLKATLEFCLSRENLANDMYLISQMDSDQYVPIVTLANLDQIKKLTTDVDLISDILKTLPLVQVDKCGEKVRPNQNRCIVILREIPEATPLEEVEALFKSDNLPKFINCEFAYNDNWFITFESEADAQLAYQYLREEVKTFQGKPIKARIKAKAIAVNTFVPKNGYRPVDVSSNVQQRYTPYYIPPVYGAQQQFPLYRLVTPQGWSATQSYLDPTLVSPFPSPAFINGFAGSPTFKSATSPLTVRHYTHAPRNRNHNKTHIRLPTDRGTTLLENPAAFSTFPTERIPNGTRPPQTHHLGSRPRLPTGLAYPRRDQVGSGRMEVNGADYSLNAGRGRRGGFGYRKRRDDNKFPRSGTQSPPPVQERTPSPSFELGLSSFPPLPGAAGNLKPEVKPENSLDNRLSDVVIGAVKDKPLNKDVVTSRVISGTPKESVQAAPAPAAQTPVDHQHSPSPAQTSPTAVEKPKETQTPAEKCSDTHAAKTTPLSNPVTVSLQQEPRKPSYAEICQRIREAPTQQPSADPRAPSSTAEDVKTPDSAERRCKESASAPAKSTATACPRETVKSQQSPGDRATAGTTASFHQS", "length": 1838 }, "evidence": [ { "id": "FB:FBgn0035424", "url": "https://alliancegenome.org/gene/FB:FBgn0035424#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZF45-1", "protein_name": "La ribonucleoprotein 4B", "gene_name": "Larp4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSDQDAKVVAEPQAQRVQEGKDSSHLMNGPISQTTSQTSSLPALTQVPTTKVSELNPNAKVWGTHMLHLEASSAAVGVNASWEEAPGRPTDCDQQGSDANGDGDKSRENAALPDAQEAEQTDMSTLALDHAEYEPLPENSDTGGNESQPESQEDPREVLKKTLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQVDEKGEKVRPNQNRCIVILREISESTPVEEVEALFKGDNLPKFINCEFAYNDNWFITFETEADAQQAYKYLREEVRTFQGKPIKARIKAKAIAINTFLPKNGFRPLDMNLYTQQRYATSFYLPPVYSPQQQFPLYSLIAPQTWSTTHSYLDPPLVTPFPSTGFINGFTSPTFKPATSPLTSLRQYPPRSRNPSKSHLRHAIPSTERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREIGTGRVEPSSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSNFPPLPGAAGNLKAEDLFENRLSSLIIGSSKERSLSTDASTNTAPVVVPREPSVPAPCAVSAAFERSPSPAHLPEWHFHRDHKVAEKQREAHSVDRLPSTPTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSSPLQPPKEQKPNTVACGKEEKKLAEPAERYREPPALKSTPGVPKDQRRQPGRRPSPPAAGKRLNREQNTPPKSP", "length": 743 }, "evidence": [ { "id": "FB:FBgn0035424", "url": "https://alliancegenome.org/gene/FB:FBgn0035424#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QDP4-1", "protein_name": "La ribonucleoprotein 4Aa isoform X1", "gene_name": "larp4aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSDQGGEPQLQEEAEPGPETRGEDEIAPGTGGDSGVMVTAKGAGLNPNAKVWQEIPATQTEAPVDGTVASPWSQNCTAEDTAVGKLYTPGFSTLEDNSTSATVVGVVNGMDPPDQSFPVCERITATNVDSKLPEEQPVSEESLRESLKKELEFCFSRENLSKDLYLISQMDSDQFVPIWTIASMEGIKVLTTDMDLILDVLRSSPMVQVDEKGEKVRPNHKRCIIILREVPETTPVEEVEALFKNDNCPKVISVEFAHNNNWYITFQSDTDAQQAYRYLREEVKTFQGKPIMARIKAINTFFAKNGYRSLDCSVYPQQSHTPPQYNSPLFMQPVYSPQQQYPLYGIVPPTWTPSPTPYFETPLAPFPNSGFVNGFSSPGHYKTGSNSLNLSRPFSRNRVPLYSRKNVINAFRNHVKPQTRTNDGLSSTVSPVALVDGLSGLHSPQPPSSAGPVLSSADLNSSFPHLASNEPTDDGTMAGRGRRTTYRGTRRRRDDDRTTRPIPLSQVKVPPPKFDLAASNFPPLPGCSASPQGEPVLENRLSDVVRGLNREKQQDSNKESTVSPTGPSSEESVSKPTQPVAKMNAHVPDPVTPSSNHLEKKPEKVEPPVYKEPPVTSAPIAAVQPTPAPTAPGPKLQPSSALPAAPQSNTAPSSTPALEPRKLSYAEVCQRPPKDPPPPASSSSPNNASAQPLRELRVNKVEEQASSPASKQERPQESGGNCKAREGRPARDSQSFSRSNGPPRSSTGGFKLREQQRRPPFGHRGSPQGGSRHAGKEQNIPPISPK", "length": 787 }, "evidence": [ { "id": "HGNC:24320", "url": "https://alliancegenome.org/gene/HGNC:24320#orthology", "database": "AGR" }, { "id": "MGI:2443114", "url": "https://alliancegenome.org/gene/MGI:2443114#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P25567-1", "protein_name": "RNA-binding protein SRO9", "gene_name": "SRO9", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSAETAAANTATAPVPEVQEQESSKSKQVNLTPAPLPTSSPWKLAPTEIPVSTISIEDLDATRKKKNRTPTPKSSTATKWVPIKASITVSGTKRSGSKNGASNGNSNKSKNNKTAASSTSSSNANRKKKHHQHNAKKQQQMKKDGFESAVGEEDSKDATSQENGQSTQQQQPPHHRNHHHSHHHNSNGPQRRKFHNSNNAGMPQNQGFPPQFKPYQGRNARNNNNNRSKYHNHFHHNQQHPQQPMVKLQQQFYPVQPVLMAINNIARQIEYYFSEENLTVDNYLRSKLSKDGFAPLSLISKFYRVVNMSFGGDTNLILAALREIVANEAATVNVAEGTLAAKEGDNVTGEAKEPSPLDKYFVRSKSWSNWLPETFETEINIEKELVGDALDQFMISLPPVPQQEEESSTELASQEQETKEDSAPVAAGESESSL", "length": 434 }, "evidence": [ { "id": "FB:FBgn0035424", "url": "https://alliancegenome.org/gene/FB:FBgn0035424#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6A0A2-1", "protein_name": "La-related protein 4B", "gene_name": "Larp4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSDQDAKVVAEPQAQRVQEGKDSSHLMNGPISQTTSQTRSLPALTQVPTTKVSELNPNAKVWGTHMLHLEASSAAVGVNAAWEEAPGHPTDCDQQVLGLDANGDGDKSRENAALPDAQEAEQTDMSTLALDHSEYEPLPENNDTGGNESQPESQEDPREVLKKTLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQVDEKGEKVRPNQNRCIVILREISESTPVEEVEALFKGDNLPKFINCEFAYNDNWFITFETEADAQQAYKYLREEVRTFQGKPIKARIKAKAIAINTFLPKNGFRPLDMNLYTQQRYATSFYLPPVYSPQQQFPLYSLITPQTWSTTHSYLDPPLVTPFPSTGFINGFTSPTFKPATSPLTSLRQYPPRSRNPSKSHLRHAIPSTERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREIGTGRVEPSSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSNFPPLPGAAGNLKTEDLFENRLSSLIIGSSKERNLSTDASTNTVPVVGPREPSVPAPCAVSAAFERSPSPVHLPEDPKVAEKQRETQSVDRLPSTPTTTACKSVQVNGAATELRKPSYAEICQRTSKDPSSSSPLQPPKEQKPSTVACGKEEKQLSEPVERHREPPALKSTPGVPKDQRRQPGRRASPPAAGKRLSKEQNTPPKSPQ", "length": 741 }, "evidence": [ { "id": "FB:FBgn0035424", "url": "https://alliancegenome.org/gene/FB:FBgn0035424#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q71RC2-1", "protein_name": "La-related protein 4", "gene_name": "LARP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLFVEQVASKGTGLNPNAKVWQEIAPGNTDATPVTHGTESSWHEIAATSGAHPEGNAELSEDICKEYEVMYSSSCETTRNTTGIEESTDGMILGPEDLSYQIYDVSGESNSAVSTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFIPIWTVANMEEIKKLTTDPDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPIEEVKGLFKSENCPKVISCEFAHNSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINTFFAKNGYRLMDSSIYSHPIQTQAQYASPVFMQPVYNPHQQYSVYSIVPQSWSPNPTPYFETPLAPFPNGSFVNGFNSPGSYKTNAAAMNMGRPFQKNRVKPQFRSSGGSEHSTEGSVSLGDGQLNRYSSRNFPAERHNPTVTGHQEQTYLQKETSTLQVEQNGDYGRGRRTLFRGRRRREDDRISRPHPSTAESKAPTPKFDLLASNFPPLPGSSSRMPGELVLENRMSDVVKGVYKEKDNEELTISCPVPADEQTECTSAQQLNMSTSSPCAAELTALSTTQQEKDLIEDSSVQKDGLNQTTIPVSPPSTTKPSRASTASPCNNNINAATAVALQEPRKLSYAEVCQKPPKEPSSVLVQPLRELRSNVVSPTKNEDNGAPENSVEKPHEKPEARASKDYSGFRGNIIPRGAAGKIREQRRQFSHRAIPQGVTRRNGKEQYVPPRSPK", "length": 724 }, "evidence": [ { "id": "FB:FBgn0035424", "url": "https://alliancegenome.org/gene/FB:FBgn0035424#orthology", "database": "AGR" }, { "id": "HGNC:24320", "url": "https://alliancegenome.org/gene/HGNC:24320#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100729-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100729-2#orthology", "database": "AGR" }, { "id": "MGI:2443114", "url": "https://alliancegenome.org/gene/MGI:2443114#orthology", "database": "AGR" }, { "id": "RGD:6499275", "url": "https://alliancegenome.org/gene/RGD:6499275#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BWW4-1", "protein_name": "La-related protein 4", "gene_name": "Larp4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLFVEVTSKGTGLNPNAKVWQEIPSGNPDGTPVTEPSWHETAATSGSHPEGHTELSEDMCKEYEVMYSPSCETTRNTADVEESADGMILGPEDLSYQLYDVSGESSSAISTEDLKECLKKQLEFCFSRENLSKDLYLISQMDSDQFVPIWTVANMEEIKKLTTNTDLILEVLRSSPMVQVDEKGEKVRPSHKRCIVILREIPETTPVEEVKALFKNENCPKVISCEFAHNSNWYITFQSDTDAQQAFKYLREEVKTFQGKPIMARIKAINTFFAKNGYRLMDSSMYTQPIQTPTQYPSPVFMQPVYNPQQYSVYSLVPQSWSPSPAPYFETPLAPFPNGSFVNGFSSPGSYKTNAAAMNMGRPFPKNRVKPHFRSSSGSEHSTEGSVSLGDGPLSRSSSRIFLSERHNPTVTGQQEQTYLPKEAPILQMEQNGDFGRGRRTLFRGRRRRDDDRIPRPQPAATEAKAPTPKFDLLATNFPPLPGSSSRVPDELGLENRMSDVVKGVCREKDSEDVRVSCPVPAEDGQTDCTSAPLSISPSPPCTAEPPVLSTTQQEQDQMEDSAVPKDTLNPVAVPVSSPTATKPSPANTASPCTSNINPPRAVALQEPRKLSYAEVCQKPPKEPSPVLVQPLRELRSNAVSPTRNEENGAPEKPVEKPHEKPETRASKDHSGFRGNTIPRGAAGKIREQRRQFSHRATPQGVTRRNGKEQYVPPRSPK", "length": 719 }, "evidence": [ { "id": "FB:FBgn0035424", "url": "https://alliancegenome.org/gene/FB:FBgn0035424#orthology", "database": "AGR" }, { "id": "HGNC:24320", "url": "https://alliancegenome.org/gene/HGNC:24320#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100729-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100729-2#orthology", "database": "AGR" }, { "id": "MGI:2443114", "url": "https://alliancegenome.org/gene/MGI:2443114#orthology", "database": "AGR" }, { "id": "RGD:6499275", "url": "https://alliancegenome.org/gene/RGD:6499275#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q92615-1", "protein_name": "La-related protein 4B", "gene_name": "LARP4B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSDQDAKVVAEPQTQRVQEGKDSAHLMNGPISQTTSQTSSIPPLSQVPATKVSELNPNAEVWGAPVLHLEASSAADGVSAAWEEVAGHHADRGPQGSDANGDGDQGHENAALPDPQESDPADMNALALGPSEYDSLPENSETGGNESQPDSQEDPREVLKKTLEFCLSRENLASDMYLISQMDSDQYVPITTVANLDHIKKLSTDVDLIVEVLRSLPLVQVDEKGEKVRPNQNRCIVILREISESTPVEEVEALFKGDNLPKFINCEFAYNDNWFITFETEADAQQAYKYLREEVKTFQGKPIKARIKAKAIAINTFLPKNGFRPLDVSLYAQQRYATSFYFPPMYSPQQQFPLYSLITPQTWSATHSYLDPPLVTPFPNTGFINGFTSPAFKPAASPLTSLRQYPPRSRNPSKSHLRHAIPSAERGPGLLESPSIFNFTADRLINGVRSPQTRQAGQTRTRIQNPSAYAKREAGPGRVEPGSLESSPGLGRGRKNSFGYRKKREEKFTSSQTQSPTPPKPPSPSFELGLSSFPPLPGAAGNLKTEDLFENRLSSLIIGPSKERTLSADASVNTLPVVVSREPSVPASCAVSATYERSPSPAHLPDDPKVAEKQRETHSVDRLPSALTATACKSVQVNGAATELRKPSYAEICQRTSKEPPSSPLQPQKEQKPNTVGCGKEEKKLAEPAERYREPPALKSTPGAPRDQRRPAGGRPSPSAMGKRLSREQSTPPKSPQ", "length": 738 }, "evidence": [ { "id": "FB:FBgn0035424", "url": "https://alliancegenome.org/gene/FB:FBgn0035424#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9I7T7-1", "protein_name": "La-related protein Larp4B", "gene_name": "Larp4B", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEYFLGGYVYMNGDALKIQPPVYTNVPVETAMLATNLFGATTQIAASPAAAAAAHIPLITAAAAAAAAAGAPAVAPPVAVAPVATASAAQAAVVPAQQQQQAHPHQAQILAHTHVAHQQQQQQQQQTIQQHLHQQQQQQSPHPAQHLTYGHQPALSQATAGGSGTISGGAVGPSGVVVEGQDTNEYAIMNGALGQTQDGTVVCYTTDALNNTNLVALDPQPHQIVVPVQVPVQVPVPVQLPANGSADPQQGSHNAAGGEEPNIPLDKLKQMLATQLEYYFSRENLANDTYLLSQMDSDQYVPIYTVARFNLVRKLTNDINLITEVLRESPNVQVDDKGLRVRPNRKRCIIILREISNNTPLDDVKALFSNESCPRPISCEFAANNSWYITFESDEDAQKAYKYLREEVKEFQGKPIMARIKPKSFINRIQAVPKNGYRLTSPPTANVFDPAGAGGATVSYAAAQQPRYLYTNGAAIAAPASVQYSNPVLIPIPQNQFYPGLVAGPWPPGTVAATTAHGQNFYELGGNIFTTNPLPPQPVTAGFAQAPPPTSQAMVTPKPQGGGRYNNNHRGNPNNVGGANSGPRAESRSKPPRSTPSASHIQGGNIMPIQITAPIPGGMVSVVPTNIVQDPLQPAPLQQQPQQVIQQIQQQPSSSAQQQQAATVQMNNTTRHYPIKSNWKGGMQKNLDKSYSGGVATHHHYTTQVQALPAHSHHLQAQQQLQGQTQQQHYQLASSSAASAPQVTYVTTAPAPQQPGQHQHHLVVQQTQPQQQQQQQQVVLQQQQVQVQELQEAGDGVEHSSHAMQQVNRSSNMSASSSSSLATSMSKEPLQWQNRPRRRRRDEEGGINYSPGGRVGLYGSSPSNPHPQQHLMSSSTGSNVQSAGGTDGGGASHRGGERQSHYNTIHDVPPPQHRGNYKGNNYNPHYHAQHSSMASGSHHHHHHNALSSQQQQHHLTTGTGQQGSGHHYHHHHHHNSIGSNVGNSGGLGVSSGGSGGGGSGGGSGSNSLSGGSNERGIHHSSLGYQGHQHQHQQQQQQQQQQQQQQPAAPVQPPQFDLEDAAFPPLPATSATAPHTPQATGGASLHNSTTSSSSSTGLGQKQTLHQQQQQAPQQHQVLSSSVESAGGDEQRSSNQQGIETSNIHLANSSTANNWVENRLSDVVRTGGGGGGGGKGKARKDNRHPQGQNQPHMAPNYQQHQPRNPPVSPTPALGAEYGIQIQEGNNTKNVTKQSSSNNNSIHVIKCQTPNINASSKEEAAGAQQQQQQQLDKSNKTEDEMHPKQPSQQRLVEGYVQQQQLPLLAAHNEYSAALAAGAGACSVVEGGLTTSLAECSLGQHKKPPSVAALHAKKDANLLEKGASKHKSVATSTSTENLSAAATASKLSYAQVAQHHKAAASSDSKETGSGGSTGTLSPTGSHKMDLVFGDPAVVVAAVEKSGLATVSTEKRVAGGASPAALIGKPAGGLPATNTTQGSSAVVVSAKEKDNRPNASVRPLSKEKQQQHYGSATEHNTNANIGLGASGNRKSRANNS", "length": 1531 }, "evidence": [ { "id": "FB:FBgn0035424", "url": "https://alliancegenome.org/gene/FB:FBgn0035424#orthology", "database": "AGR" }, { "id": "HGNC:24320", "url": "https://alliancegenome.org/gene/HGNC:24320#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100729-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100729-2#orthology", "database": "AGR" }, { "id": "MGI:2443114", "url": "https://alliancegenome.org/gene/MGI:2443114#orthology", "database": "AGR" }, { "id": "RGD:6499275", "url": "https://alliancegenome.org/gene/RGD:6499275#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRY7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" }, { "start_pos": 720, "end_pos": 722, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PRY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRY7" }, { "id": "PS50961", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50961" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH La-type RNA-binding", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 221, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 346, 624, 669, 675 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 358, "end_pos": 360 }, { "start_pos": 435, "end_pos": 437 }, { "start_pos": 720, "end_pos": 722 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 4 }, { "field": "total_sites", "count": 4 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 4 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 4 }, { "field": "exact_o_linked_sites", "count": 4 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPP9-1", "uniprot_ac": "A0A8M9PPP9", "uniprot_id": "A0A8M9PPP9_DANRE", "mass": { "chemical_mass": 115676.0, "monoisotopic_mass": 115676.0 }, "refseq": { "ac": "XP_021324231", "name": "sentrin-specific protease 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324231" }, "gene_names": [ { "name": "senp6a", "type": "recommended", "evidence": [ { "id": "A0A8M9PPP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9" } ] }, { "name": "senp6a", "type": "synonym", "evidence": [ { "id": "XP_021324231", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324231" } ] } ], "protein_names": [ { "name": "Sentrin-specific protease 6 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PPP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9/entry#names_and_taxonomy" } ] }, { "name": "sentrin-specific protease 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021324231", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324231" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021324231.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324231", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324231" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "senp6a", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080204-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-25", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "503939", "url": "https://www.ncbi.nlm.nih.gov/gene/503939", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051947", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051947", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:503939", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:503939", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PPP9", "url": "https://www.orthodb.org/?gene=A0A8M9PPP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46896", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46896", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46896:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46896:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02902", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02902", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021324231", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324231", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PHN4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PHN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PHN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPQ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T747", "url": "https://www.uniprot.org/uniprotkb/A0AB32T747", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T747-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T747-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080204-25", "url": "https://zfin.org/ZDB-GENE-080204-25", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNNKKSPFIEALDKCEDRRDGGFKQTWRCSLSDDSEDDSRHDAALVTMERVSGQQELSSEGIKTPSSTKRFSANGSVETHDRRPHQLKPLNRTGKLSDAAHSVSMSPLPNRTSFLIMSPAPQAVVVQGRVFQHAQLSTPIRKLEHRSDLIQRGQMDSIVLTCPEISDPGDLSIKRRVHQKRRIGESPVTVSQVVEQPLQPDDYLTVCGECGQPSEDHVKCDHCGFILPNETKPRPAIPSALLPRPSIRPQPASLQISKGFYECSQQLDVIVNPSVRITPGNLLFPHNGRPSGSLACNGHKAAGGAKQQLNKPCELNDPIVLSSDEDDESDNMSSTGTANRLDSVSPRPADSAHSSPAPSDGRLEAVVKAAGEHEDSSADFFTHTNHRNLLPRRNRMKDPFGNLVSDDATVSKRRKINQEQKLSSIILECRSVRIGTLRRMVTKPVVFTVDFIQLETEGREVDVLESVSLKSSELTRCEWCNVKKLPVLFLQTSDQECQRLQTQLQMSQDSGGIWYDCNGNNDEKYIVLIFEHGPSMHEQVILEDILTEIGRNNRLADFPSKISFDEANVRLVNYNKASLEKEKVKVEKAEVVAAPSSSALLATPSLSVVTVAVAPVNTAPAVPVPCAAPSVQTRLSARLQEFCDDDDEMAELQPTFTGPIIKLLVYPPPPAKGGITVTNEDLHCLSDGEFLNDVIIDFYLKYLFLEKLKKEDAARSHVFSSFFYKRLNQRERRNTVDTSSLPIQKRKHNRVKTWTRHVDLFQKDFIFVPINESAHWYLAVICFPGLESAQVEPNPLYQPQTAVSSSPPTDGASEQRDQFSQNTAGPHRADANQVQFTDGLRRIIEYSTEDDSHQSDDQSSCQDECSEDGALADDSGSFDRAEWTSKPTICKQPCILIMDSLRGPTRSTVVKTLREYLEVEWEVKKGSKRSFGKELMKGSSPRVPQQDNFSDCGVYVLQYVESFFESPLPSFHLPMNLLEWFPQQRMKTKREEIKDLILKLQTQQQLSLESSEQTDGAHSPYEDSLESADLIPSVSS", "length": 1036, "header": "tr|A0A8M9PPP9-1|A0A8M9PPP9_DANRE Isoform 1 of Sentrin-specific protease 6 isoform X1 OS=Danio rerio OX=7955 GN=senp6a PE=1 SV=2 CANONICAL=A0A8M9PPP9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PHN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9/entry#A0A8M9PHN4-1", "sequence": { "sequence": "MNNKKSPFIEALDKCEDRRDGGFKQTWRCSLSDDSEDDSRHDAALVTMERVSGQQELSSEGIKTPSSTKRFSANGSVETHDRRPHQLKPLNRTGKLSDAAHSVSMSPLPNRTSFLIMSPAPQAVVVQGRVFQHAQLSTPIRKLEHRSDLIQRGQMDSIVLTCPEISDPGDLSIKRRVHQKRRIGESPVTVSQVVEPLQPDDYLTVCGECGQPSEDHVKCDHCGFILPNETKPRPAIPSALLPRPSIRPQPASLQISKGFYECSQQLDVIVNPSVRITPGNLLFPHNGRPSGSLACNGHKAAGGAKQQLNKPCELNDPIVLSSDEDDESDNMSSTGTANRLDSVSPRPADSAHSSPAPSDGRLEAVVKAAGEHEDSSADFFTHTNHRNLLPRRNRMKDPFGNLVSDDATVSKRRKINQEQKLSSIILECRSVRIGTLRRMVTKPVVFTVDFIQLETEGREVDVLESVSLKSSELTRCEWCNVKKLPVLFLQTSDQECQRLQTQLQMSQDSGGIWYDCNGNNDEKYIVLIFEHGPSMHEQVILEDILTEIGRNNRLADFPSKISFDEANVRLVNYNKASLEKEKVKVEKAEVVAAPSSSALLATPSLSVVTVAVAPVNTAPAVPVPCAAPSVQTRLSARLQEFCDDDDEMAELQPTFTGPIIKLLVYPPPPAKGGITVTNEDLHCLSDGEFLNDVIIDFYLKYLFLEKLKKEDAARSHVFSSFFYKRLNQRERRNTVDTSSLPIQKRKHNRVKTWTRHVDLFQKDFIFVPINESAHWYLAVICFPGLESAQVEPNPLYQPQTAVSSSPPTDGASEQRDQFSQNTAGPHRADANQVQFTDGLRRIIEYSTEDDSHQSDDQSSCQDECSEDGALADDSGSFDRAEWTSKPTICKQPCILIMDSLRGPTRSTVVKTLREYLEVEWEVKKGSKRSFGKELMKGSSPRVPQQDNFSDCGVYVLQYVESFFESPLPSFHLPMNLLEWFPQQRMKTKREEIKDLILKLQTQQQLSLESSEQTDGAHSPYEDSLESADLIPSVSS", "length": 1035, "header": "tr|A0A8M9PHN4-1|A0A8M9PPP9_DANRE Computationally mapped isoform of Sentrin-specific protease 6 isoform X1 OS=Danio rerio OX=7955 GN=senp6a PE=1 SV=2 CANONICAL=A0A8M9PPP9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PPP9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9/entry#A0A8M9PPP9-1", "sequence": { "sequence": "MNNKKSPFIEALDKCEDRRDGGFKQTWRCSLSDDSEDDSRHDAALVTMERVSGQQELSSEGIKTPSSTKRFSANGSVETHDRRPHQLKPLNRTGKLSDAAHSVSMSPLPNRTSFLIMSPAPQAVVVQGRVFQHAQLSTPIRKLEHRSDLIQRGQMDSIVLTCPEISDPGDLSIKRRVHQKRRIGESPVTVSQVVEQPLQPDDYLTVCGECGQPSEDHVKCDHCGFILPNETKPRPAIPSALLPRPSIRPQPASLQISKGFYECSQQLDVIVNPSVRITPGNLLFPHNGRPSGSLACNGHKAAGGAKQQLNKPCELNDPIVLSSDEDDESDNMSSTGTANRLDSVSPRPADSAHSSPAPSDGRLEAVVKAAGEHEDSSADFFTHTNHRNLLPRRNRMKDPFGNLVSDDATVSKRRKINQEQKLSSIILECRSVRIGTLRRMVTKPVVFTVDFIQLETEGREVDVLESVSLKSSELTRCEWCNVKKLPVLFLQTSDQECQRLQTQLQMSQDSGGIWYDCNGNNDEKYIVLIFEHGPSMHEQVILEDILTEIGRNNRLADFPSKISFDEANVRLVNYNKASLEKEKVKVEKAEVVAAPSSSALLATPSLSVVTVAVAPVNTAPAVPVPCAAPSVQTRLSARLQEFCDDDDEMAELQPTFTGPIIKLLVYPPPPAKGGITVTNEDLHCLSDGEFLNDVIIDFYLKYLFLEKLKKEDAARSHVFSSFFYKRLNQRERRNTVDTSSLPIQKRKHNRVKTWTRHVDLFQKDFIFVPINESAHWYLAVICFPGLESAQVEPNPLYQPQTAVSSSPPTDGASEQRDQFSQNTAGPHRADANQVQFTDGLRRIIEYSTEDDSHQSDDQSSCQDECSEDGALADDSGSFDRAEWTSKPTICKQPCILIMDSLRGPTRSTVVKTLREYLEVEWEVKKGSKRSFGKELMKGSSPRVPQQDNFSDCGVYVLQYVESFFESPLPSFHLPMNLLEWFPQQRMKTKREEIKDLILKLQTQQQLSLESSEQTDGAHSPYEDSLESADLIPSVSS", "length": 1036, "header": "tr|A0A8M9PPP9-1|A0A8M9PPP9_DANRE Isoform 1 of Sentrin-specific protease 6 isoform X1 OS=Danio rerio OX=7955 GN=senp6a PE=1 SV=2 CANONICAL=A0A8M9PPP9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PPQ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9/entry#A0A8M9PPQ4-1", "sequence": { "sequence": "MERVSGQQELSSEGIKTPSSTKRFSANGSVETHDRRPHQLKPLNRTGKLSDAAHSVSMSPLPNRTSFLIMSPAPQAVVVQGRVFQHAQLSTPIRKLEHRSDLIQRGQMDSIVLTCPEISDPGDLSIKRRVHQKRRIGESPVTVSQVVEQPLQPDDYLTVCGECGQPSEDHVKCDHCGFILPNETKPRPAIPSALLPRPSIRPQPASLQISKGFYECSQQLDVIVNPSVRITPGNLLFPHNGRPSGSLACNGHKAAGGAKQQLNKPCELNDPIVLSSDEDDESDNMSSTGTANRLDSVSPRPADSAHSSPAPSDGRLEAVVKAAGEHEDSSADFFTHTNHRNLLPRRNRMKDPFGNLVSDDATVSKRRKINQEQKLSSIILECRSVRIGTLRRMVTKPVVFTVDFIQLETEGREVDVLESVSLKSSELTRCEWCNVKKLPVLFLQTSDQECQRLQTQLQMSQDSGGIWYDCNGNNDEKYIVLIFEHGPSMHEQVILEDILTEIGRNNRLADFPSKISFDEANVRLVNYNKASLEKEKVKVEKAEVVAAPSSSALLATPSLSVVTVAVAPVNTAPAVPVPCAAPSVQTRLSARLQEFCDDDDEMAELQPTFTGPIIKLLVYPPPPAKGGITVTNEDLHCLSDGEFLNDVIIDFYLKYLFLEKLKKEDAARSHVFSSFFYKRLNQRERRNTVDTSSLPIQKRKHNRVKTWTRHVDLFQKDFIFVPINESAHWYLAVICFPGLESAQVEPNPLYQPQTAVSSSPPTDGASEQRDQFSQNTAGPHRADANQVQFTDGLRRIIEYSTEDDSHQSDDQSSCQDECSEDGALADDSGSFDRAEWTSKPTICKQPCILIMDSLRGPTRSTVVKTLREYLEVEWEVKKGSKRSFGKELMKGSSPRVPQQDNFSDCGVYVLQYVESFFESPLPSFHLPMNLLEWFPQQRMKTKREEIKDLILKLQTQQQLSLESSEQTDGAHSPYEDSLESADLIPSVSS", "length": 989, "header": "tr|A0A8M9PPQ4-1|A0A8M9PPQ4_DANRE Computationally mapped isoform of Sentrin-specific protease 6 isoform X3 OS=Danio rerio OX=7955 GN=senp6a PE=1 SV=2 CANONICAL=A0A8M9PPP9-1" }, "locus": {} }, { "isoform_ac": "A0AB32T747-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9/entry#A0AB32T747-1", "sequence": { "sequence": "MERVSGQQELSSEGIKTPSSTKRFSANGSVETHDRRPHQLKPLNRTGKLSDAAHSVSMSPLPNRTSFLIMSPAPQAVVVQGRVFQHAQLSTPIRKLEHRSDLIQRGQMDSIVLTCPEISDPGDLSIKRRVHQKRRIGESPVTVSQVVEPLQPDDYLTVCGECGQPSEDHVKCDHCGFILPNETKPRPAIPSALLPRPSIRPQPASLQISKGFYECSQQLDVIVNPSVRITPGNLLFPHNGRPSGSLACNGHKAAGGAKQQLNKPCELNDPIVLSSDEDDESDNMSSTGTANRLDSVSPRPADSAHSSPAPSDGRLEAVVKAAGEHEDSSADFFTHTNHRNLLPRRNRMKDPFGNLVSDDATVSKRRKINQEQKLSSIILECRSVRIGTLRRMVTKPVVFTVDFIQLETEGREVDVLESVSLKSSELTRCEWCNVKKLPVLFLQTSDQECQRLQTQLQMSQDSGGIWYDCNGNNDEKYIVLIFEHGPSMHEQVILEDILTEIGRNNRLADFPSKISFDEANVRLVNYNKASLEKEKVKVEKAEVVAAPSSSALLATPSLSVVTVAVAPVNTAPAVPVPCAAPSVQTRLSARLQEFCDDDDEMAELQPTFTGPIIKLLVYPPPPAKGGITVTNEDLHCLSDGEFLNDVIIDFYLKYLFLEKLKKEDAARSHVFSSFFYKRLNQRERRNTVDTSSLPIQKRKHNRVKTWTRHVDLFQKDFIFVPINESAHWYLAVICFPGLESAQVEPNPLYQPQTAVSSSPPTDGASEQRDQFSQNTAGPHRADANQVQFTDGLRRIIEYSTEDDSHQSDDQSSCQDECSEDGALADDSGSFDRAEWTSKPTICKQPCILIMDSLRGPTRSTVVKTLREYLEVEWEVKKGSKRSFGKELMKGSSPRVPQQDNFSDCGVYVLQYVESFFESPLPSFHLPMNLLEWFPQQRMKTKREEIKDLILKLQTQQQLSLESSEQTDGAHSPYEDSLESADLIPSVSS", "length": 988, "header": "tr|A0AB32T747-1|A0A8M9PPP9_DANRE Computationally mapped isoform of Sentrin-specific protease 6 isoform X1 OS=Danio rerio OX=7955 GN=senp6a PE=1 SV=2 CANONICAL=A0A8M9PPP9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 278, "start_aa": "Thr", "end_pos": 278, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr278", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 603, "start_aa": "Thr", "end_pos": 603, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr603", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:503939", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:503939", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B8Q7-1", "protein_name": "Sentrin-specific protease 7b isoform X1", "gene_name": "senp7b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPDTYRESFRQACALLFLQMAVSFRIPKKKQPSDSCSLDMQSPLSRLQDDNSQKSQWGSVTFNGRTPHKTSSNENMLSKDSQRSDSLRGATRGRFSFKMNQQPIKISPARVNGTPHKVSDTSGFRPQCQTPTTAPDFTANNRWRPKRASDRLLSHDENHTKASECSAFKIHRGLDSEELEEEETEGTQGHSQVKETQRATSSEDYKVTSAASVFEKATSKHKNGTEKAVSKPFNHSGLHVQEAPARHLRTSEERAASSVPVRKDPLTSETAENKSKDPFASFYSSKLRRKPQSFCKTYKRTKPSSTEPIVLSSDDEGANEVNDVSGGLQEQRISEGIRDTQTGNQKSSKTNVGGERSTTKVEVPSIMELEFSRLHYDTIQAQANGTVVITDEGISIPLKDADGEGEVAISISCSQLQMYGMWDGGLASDGSLLSITEEPAPSLFFLMVSDAQARLLRKELSLQYNTHTSGQACPFVLLVLSGQLDDLRVALLASLMDVIGLRYAQDSLSNPVSWADGLSRLLCHPRGEHFLSLLGQNCKDTGQDKAKENASGIKEPTARRPLRSHSKPQSLPRRLIQYPPPPSKGGITVTTEDLECLKDGEFLNDVIIDFYLKYLLLERADKDIAERSHIFSSFFYKQLTRKDTSGPEETGSTSAYRRHQRVRTWTRHVDIFSKDYLFIPVNHEAHWYLVLICFPALERPQIVEWRQKSSVSQDESQTTKERPSGESQRESSQQPKGNPSKINESRSHNLPDCTVHSCTKETICKRPCILIMDSLKLSYHQRTYTLLREYLQVEWEVRKGSCRSFSNESITGSLCRVPLQDNSSDCGLYLLQYVESFLQNPVVDFALPLRLDQWFPRSQVRKKREDLRELVLLLYRRQTEPRAT", "length": 884 }, "evidence": [ { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QBG7-1", "protein_name": "Sentrin-specific protease 7 isoform X1", "gene_name": "si:dkey-100n23.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPDERKHNSTLSDSSNITPERRRALILSPEIKRDSRQTECPYKIARRGSAAEDECVETEMSKDRKSNNKIHWTQLASNGTSSQLSPKSTKKSNQELTILQKIHRNQVKVVLEDVLLTELGQSLLRCSGHTFQKTNQSESKKRSDQTSTPTLKNKTRTSLTKRGETNSTEPKATSPFHNNIESKSKSLNSSQKLLESSELSSNSRSPRESESPQAALISKESPIQTSSSSFEENEVTLIEGSLQNEEVLSAVCESVISSSSPVETRRRPREKKADSELLSNKKERRESQESPKDAAKHEENHLCSNGELVQEVEGMRGSVLRLSAGTDFQIPVKRCRLDSLSEDQLLNSDLAFDTAEIRSFTLESSNFSQDETIVLSSEEEDEGEGREETKISALNIQPPEGTKDTNVVDESTTVYEQTKSPESNLSITEMSEEESQGIPLPLSSLHMGGVSAKSSGIMMITPYKITFSLKGNSSDSTVKISLSAINVYKYSLWEEHTLWGCDLDKDNEATPTSLLFLWLSDAQAHKLHDDLSVLELGTRPAESSTCLLLCMAEPLSGIESALLCSLLDIVVSNQGSPELYCTCLTQSDSLNLLQSSEETHLLQLLTPKPDEQTSTSAQSQDSDVQLEPTYTLCHRRAQGSYNVFLAATPGAEWTPYKHCGPTRRLIQFPPPPSKGALTVTTEDLECLDSGEFLNDVIIDFYLKYLLVQKAPQASVARSHIFSSFFYKQLTRRDNANEDSTSTPAQVRRHQRVRTWTRHVDIFEKDFLFVPVNQEAHWYLVVICFPGLEDPQYVKRDDSASVQGNGGEDVGESENETQGDHRSNSDEDKSTDDSRIKSSTSLRQPDCTENTCKKDVVLKRPCILIMDSLKLSIHERIFKLLREYLQVEWETKRMGTRDFSAERMVGSHCKVPLQDNSSDCGLYLLQYAESFLQDPVVHFDLPLRLERWFPRQQVRGKRDEIRDLILHLYRFQKGSLGNDAADDRTDYGNVIK", "length": 991 }, "evidence": [ { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HPH5-1", "protein_name": "Sentrin-specific protease 6 isoform X1", "gene_name": "senp6b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVRPLGQNRKNSLKVKPLKGNATGLNLLGMRTILANQTPSLVKTKGKRFIYALQSSWMKESRTDLSNSQSIDVCVIEDNETTDVLKHSVKDTQLEDFYSDILDHKKSTFKENDNTSLKILRKYRMRDEFGNLNPRVKRKTPAAKKKEPNSQIAQRLNSLMLNIRCLKVGTLTKTFARSGSLSTQCTFTVDCIEISSEAGRIEASDIVACEWCTVPRLPALFLQTTYEARLHLQVQLDMLEDDSEHFQNKNEKETCIVLIFENELTLPEQIILEDIFTEIGMRHNISGFLVKLPFEEANNKLKAQISAQKQIAMLHLEEDELPASSQRALMPFPPSPDAPRHEIATLSISDSDENDLMEGHSSPVQDLKKLLVYPPSPAKGGITVTEEDFYCLDEGEFLNDVIVDFYLRYLVCKQQEKKDTTQYHVFSSFFFKHLTQGNQKRHSGATSLSPQECRHDRVKTWTRNVNLFEKDFVFVPINQMSHWYLAVICFPGQISQTSGLDLSLNERRHSRQYLCAPSPPNPMSLFYSPESSKQLSRWSQSIDDLDQSFEILSDDEAEDDLQVVTNRSVLNRGSDVSKKPCILIMDSLTSSGRSSEVQILQQYLQEEWRVKMGSQQSFEKMHGWSPIVPKQDNYTDCGIYLLQYVESFLKDPPQAFHHNMDLKGWFSQRTVKRKRLQIKELILKLHRQQ", "length": 689 }, "evidence": [ { "id": "HGNC:20944", "url": "https://alliancegenome.org/gene/HGNC:20944#orthology", "database": "AGR" }, { "id": "MGI:1922075", "url": "https://alliancegenome.org/gene/MGI:1922075#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZF42-1", "protein_name": "Sentrin-specific protease 7", "gene_name": "Senp7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRARPGRRRASSEIVTEGKRKKSSPADLQKITKLLTVKSEDVLAQSPLPKLRGSECWWTRSLRNKVICLDHKTTKAAHGCPPKALPKRHLKVMLTNVLWTDLGREFRKTLPRNDAKLCDTSKVQSDSLPSTSVDSIETCQRLDPLHQSLNLSERIPRVILTDIRQTELGRKYLKIPSVTEASLSDTASPKSEELSSSADGSLESCQNVNHLKSFLSERGSKPSRTGDISAKEAANGRQEQGDDGDIAPEMVTPQSKDFNSGNKGDYHEEGTSNKNTSYSHSETDHTPVSRKRKKRGRSNFHNSHNPKSSVDKSTEYIKEEENESTVSSKLEESNEDSHQDPAPPEGLTPDSLETEATNVCSFVVQEPDVSAASGRACSPNKSSESSVSSEVAENSSAAEKGEASTVKEAPPPGGNSEENQLLMSAEPIVVSSDEEGPVEHKNSVILKLQPSQDYEFMSENQTTSDPQLSELMLGACESVQVSSELCPYNPDMENISCINPNSEMDLKLDFIFTCVYIGKIKGTSKGCITFTKKYIKIPFQVSMNEISLTVDTARLKRFGLWESKDDDHSKRSHAILFLWVSSNYLQDIQTQLENPMLSQQSKANEFIFLELNSPISQREELKLKDIMMEIGATNGELQLSCPLPWVQAFPLFQDLSPQEISFLHYYCASASSFPAVAGADMKKKPVSQPSNADVVKPTYTFLHKQSSGCYSLSITSSPDEEWREVRNTGPVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLLLEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPDLSVAQRRHRRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQEFQDQQSQHDNKTIDNDPHTTSTVFTSAEESQSTETSMSVPKKMCKRPCILILDSLKAASIQNTVQNLREYLEVEWEVKRKTHREFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFQDPIVNFELPIHLEKWFPRHVIKTKREDIRELILKLHLQQQKGSSS", "length": 1037 }, "evidence": [ { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LU78-1", "protein_name": "Sentrin-specific protease 6", "gene_name": "Senp6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGKSGGSAGGVFLKALARSESKRDGGFKNNWSFDHEEESEGDADKDGANLLSVEDEDSETSKGKKLNRRSEIVATSSGDFILKTYVRRNKTDGFKTLKGNAIGLNMLSNNKKLSENTQATALCSGTVVHGRRFHHAHVQMPGIKTAAQSNQDRKERKEYPPHVHKAENNPVMLSHGQGGDHVMKKTEDSESYVEPEVKRKVQQKRHCSTYQLSPLSPASKKCLTHFEVSEQRECCPKCGKEKENQTRCQSCGIVFHNDLQRNCRQAVTLNESTGPLLRTSIHQNSGGQKSQNTGLTAKKFYGNSVDKIPIDILLTCDGSRHNYIQTNGKVILPGGKIPKITNPKERKTSVSDLNDPIILSSDDDDDDDRTKRRESTSPQPADSACSSPAPSTGKVEAALNANTCRAEQEPRSSPAESELNTVVIPRKARMKDQLGNSISTPLKRRKVNTHGALIPVTSLSCQDFGSVILNCRSIRVGTLFRLLVEPVIFSLELIKIRLDGPDSVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSLQLQMSKEDKVWNDCKGINRITSLEEQYIILIFQTGLDHQADVVFESIITDIGIRNNVCNFFAKIPFEEANSRLVACTRSYEESIKGNCVQKENKVKTVSFESKIQLRSKQELQFFDDEEEAGESHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNSETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVMQKPSRAEDSYVSSASEVDACSQNSAAKPVIKKMLHRKHCLAVTDSSAAQEDSEPCYRRNAYSVKCSMKKKNHAVHENEEPSNGESACQEISDRTESEHGLQDECLNSAHHPDALSKIRLNYGDQSAEGGKLLEDELIDFSEDQDDPDDSSDDGLLADENYNSEIGQWHLKPTVCKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILNFELPMNLVNWFPPPRMKTKREEIRNIILKLQEEQSKEKRLLRDTSSAETSLGEGAEQYASSVSE", "length": 1135 }, "evidence": [ { "id": "FB:FBgn0035713", "url": "https://alliancegenome.org/gene/FB:FBgn0035713#orthology", "database": "AGR" }, { "id": "HGNC:20944", "url": "https://alliancegenome.org/gene/HGNC:20944#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-25#orthology", "database": "AGR" }, { "id": "RGD:1304565", "url": "https://alliancegenome.org/gene/RGD:1304565#orthology", "database": "AGR" }, { "id": "MGI:1922075", "url": "https://alliancegenome.org/gene/MGI:1922075#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P40537-1", "protein_name": "Ubiquitin-like-specific protease 2", "gene_name": "ULP2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSARKRKFNSLKPLDTLNSSRASSPRSSASLPPKRYNTFRKDPKIVDHLNNASTKDFLPVLSMNSESKRQIELSDNDVDNNDEGEGVNSGCSDQDFEPLQSSPLKRHSSLKSTSNGLLFQMSNNLGNGSPEPAVASTSPNGSIISTKLNLNGQFSCVDSKTLRIYRHKAPCIMTFVSDHNHPKFSLYFQQSVIYNSQVNLLDDVELIILDKKNSFMAIILKDLKKVKMILDVNNSSININTNILIWSTASSASNKKIKSIKRFLLMSYSSSIKVEILDHKEQILERLKHLIHPISSSSPSLNMERAINSTKNAFDSLRLKKTKLSTNDDESPQIHTHFLSNKPHGLQSLTKRTRIASLGKKEHSISVPKSNISPSDFYNTNGTETLQSHAVSQLRRSNRFKDVSDPANSNSNSEFDDATTEFETPELFKPSLCYKFNDGSSYTITNQDFKCLFNKDWVNDSILDFFTKFYIESSIEKSIIKREQVHLMSSFFYTKLISNPADYYSNVKKWVNNTDLFSKKYVVIPINISYHWFSCIITNLDAILDFHQNKDKNDAINSDEISINNPLVNILTFDSLRQTHSREIDPIKEFLISYALDKYSIQLDKTQIKMKTCPVPQQPNMSDCGVHVILNIRKFFENPVETIDVWKNSKIKSKHFTAKMINKYFDKNERNSARKNLRHTLKLLQLNYISYLKKENLYEEVMQMEEKKSTNINNNENYDDDDEEIQIIENIDQSSKDNNAQLTSEPPCSRSSSISTTEREPTELHNSVVRQPTGEIITDNEDPVRAASPETASVSPPIRHNILKSSSPFISESANETEQEEFTSPYFGRPSLKTRAKQFEGVSSPIKNDQALSSTHDIMMPSPKPKRIYPSKKIPQLSSHVQSLSTDSMERQSSPNNTNIVISDTEQDSRLGVNSESKNTSGIVNRDDSDVNLIGSSLPNVAEKNHDNTQESNGNNDSLGKILQNVDKELNEKLVDIDDVAFSSPTRGIPRTSATSKGSNAQLLSNYGDENNQSQDSVWDEGRDNPILLEDEDP", "length": 1034 }, "evidence": [ { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" }, { "id": "FB:FBgn0035713", "url": "https://alliancegenome.org/gene/FB:FBgn0035713#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6P7W0-1", "protein_name": "Sentrin-specific protease 6", "gene_name": "Senp6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGKSGGSAGALFLKALDRSESKRDGGFKNNWSFDHEEESEGDADKDGANLLSVEDEDSEISKGKKLNRRSEIVATSSGDFILKTYVRRSKTDGFKTLKGNPIGLNMLSNNKKLSESTAGTALCSGTVVHGRRFHHAHSQTPGIRTAAQRKEYPPYVHKAENSPVMLSHGQGGDHIMKKTEESESYVESEIKRKVQQKRHCSTYQLSPLSPASKKCLTHLEVSEQREYCPKCGKEKENQTKCQSCGIVFHNDLQRNCRQAVTLNEPTGPLLRTSIHQNSGGQKSQNTGLTAKKFYGNSVDKIPIDILVTCDDSRHNYIQTNGKVILPGGKIPKLTNPKERKISVSDLNDPIILSSDDDDDDDDRTKRRESTSPKPADSACSSPVPSTGKVEAALNADACRAEQEPRSSPAEPELNTIVIPRKARMKDQLGNSISTPLKRRKVNSHAAFIHPMSLSCQNFESVILNCRSIRVGTLFRLLVEPVIFSLESITIHLDGPESDPVDIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSMQLQMSKEDKVWNDCKGINRITSLEEQYIILIFQTGLDHQAEVVFESIITDIGIRNNVPNFFAKILFDEANSRLVACTRSYEESIKGNCAQKENKVKTVSFESKIQLRSKQELQFFDDDEEAGESHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLSEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNPETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVMQKTPSAEDSCVSSASEMGACSQNSAAKPVIKKMLNRKHCLAVTDSSAAQEESEPCYRRNAYSVKCSMKKKNHAINENEEPSNGESTCQDICDRTQSENGLRDECFSSVHHPDALSKIRLNYGDQSADGGKLLEDELIDFSEDQDDPDDSSDDGLLADENYSSEIGQWHLKPTVCKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPVLNFELPMNLMNWFPPPRMKTKREEIRNIILKLQESQSKDKKLLKDSLAETSLGDGAEQYASASGGSE", "length": 1132 }, "evidence": [ { "id": "FB:FBgn0035713", "url": "https://alliancegenome.org/gene/FB:FBgn0035713#orthology", "database": "AGR" }, { "id": "HGNC:20944", "url": "https://alliancegenome.org/gene/HGNC:20944#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-25#orthology", "database": "AGR" }, { "id": "RGD:1304565", "url": "https://alliancegenome.org/gene/RGD:1304565#orthology", "database": "AGR" }, { "id": "MGI:1922075", "url": "https://alliancegenome.org/gene/MGI:1922075#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BUH8-1", "protein_name": "Sentrin-specific protease 7", "gene_name": "Senp7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRARPGRRRASSEIVTEGKRKKSSPADLQKITKLLTVKSEDVLAQSPLSKLRGSECWWTRSLRNKVICLDHKKPKAARGCPPKGLPKRHLRVMLTNVLWTDLGREFRKTLPRKDANLCAPSKVQSDSLPSTSVDSIETCQRLDPLHQSLNLSERTPRVILTDIRQTELGRKYLKIPPVTEASLSDTANLKSEQLSSSSDGSLESCQSVNHHKSFLSESGPKPSRTGDVPAKEAACGGQKQGDDGGVTPEMAAPHPKDFNTGNKGCDYLEEGTSNKNTSYSYSEMDHTPVSRKRKKRGRSNFHDSHNSKTSLDKPTEHTKEEENDSSVSRKLEESGEDSHQDPAPPEGLAPESLESEATNLRSFAAGQEPDASAASGRASSPNKSLESSASSEVSENSSVAVKGEALTLKEASPPGGSSEESQLLISAEPIVVSSDEEGPVEHKNSVILKLQPPHEIMSENQGTSDPQLSELTLGACESVQVTSELFPYNPDVENISCIKSNSEMDLKLDFIFTCVYIGKIKGTPKGCVTFTKKYIKIPFQVSTNEISLTVDTARLKRFGLWESKDEDHSKRSHAILFLWLSSDYLQDIQTQLENPMLSQQSKANEFIFLELNSSISQREELKLKDIMMEISTKNGNLHLSCPLPWVQALPLFQDLSPQEISFLHYYYASASALPTAAGADMKKKSVSQPSNSDTIKPTYTFLHKQSSGCYSLSITSSPEEEWQEVRNTGPVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLLLEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPDLSVAQRRHRRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDCPQTVSQQFQGQQSQHDHKMTDNDPHTTSTVSTSAEDSQSTEVNMSVPKKMCKRPCILILDSLKAASIQNTVQNLREYLEVEWEVKRKTHREFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFQDPIVNFELPIHLEKWFPRHVIKTKREDIRELILKLHLQQQKGGSC", "length": 1037 }, "evidence": [ { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BQF6-1", "protein_name": "Sentrin-specific protease 7", "gene_name": "SENP7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDKRKLGRRPSSSEIITEGKRKKSSSDLSEIRKMLNAKPEDVHVQSPLSKFRSSERWTLPLQWERSLRNKVISLDHKNKKHIRGCPVTSKSSPERQLKVMLTNVLWTDLGRKFRKTLPRNDANLCDANKVQSDSLPSTSVDSLETCQKLEPLRQSLNLSERIPRVILTNVLGTELGRKYIRTPPVTEGSLSDTDNLQSEQLSSSSDGSLESYQNLNPHKSCYLSERGSQRSKTVDDNSAKQTAHNKEKRRKDDGISLLISDTQPEDLNSGSRGCDHLEQESRNKDVKYSDSKVELTLISRKTKRRLRNNLPDSQYCTSLDKSTEQTKKQEDDSTISTEFEKPSENYHQDPKLPEEITTKPTKSDFTKLSSLNSQELTLSNATKSASAGSTTETVENSNSIDIVGISSLVEKDENELNTIEKPILRGHNEGNQSLISAEPIVVSSDEEGPVEHKSSEILKLQSKQDRETTNENESTSESALLELPLITCESVQMSSELCPYNPVMENISSIMPSNEMDLQLDFIFTSVYIGKIKGASKGCVTITKKYIKIPFQVSLNEISLLVDTTHLKRFGLWKSKDDNHSKRSHAILFFWVSSDYLQEIQTQLEHSVLSQQSKSSEFIFLELHNPVSQREELKLKDIMTEISIISGELELSYPLSWVQAFPLFQNLSSKESSFIHYYCVSTCSFPAGVAVAEEMKLKSVSQPSNTDAAKPTYTFLQKQSSGCYSLSITSNPDEEWREVRHTGLVQKLIVYPPPPTKGGLGVTNEDLECLEEGEFLNDVIIDFYLKYLILEKASDELVERSHIFSSFFYKCLTRKENNLTEDNPNLSMAQRRHKRVRTWTRHINIFNKDYIFVPVNESSHWYLAVICFPWLEEAVYEDFPQTVSQQSQAQQSQNDNKTIDNDLRTTSTLSLSAEDSQSTESNMSVPKKMCKRPCILILDSLKAASVQNTVQNLREYLEVEWEVKLKTHRQFSKTNMVDLCPKVPKQDNSSDCGVYLLQYVESFFKDPIVNFELPIHLEKWFPRHVIKTKREDIRELILKLHLQQQKGSSS", "length": 1050 }, "evidence": [ { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" }, { "id": "FB:FBgn0035713", "url": "https://alliancegenome.org/gene/FB:FBgn0035713#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9GZR1-1", "protein_name": "Sentrin-specific protease 6", "gene_name": "SENP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAGKSGGSAGEITFLEALARSESKRDGGFKNNWSFDHEEESEGDTDKDGTNLLSVDEDEDSETSKGKKLNRRSEIVANSSGEFILKTYVRRNKSESFKTLKGNPIGLNMLSNNKKLSENTQNTSLCSGTVVHGRRFHHAHAQIPVVKTAAQSSLDRKERKEYPPHVQKVEINPVRLSRLQGVERIMKKTEESESQVEPEIKRKVQQKRHCSTYQPTPPLSPASKKCLTHLEDLQRNCRQAITLNESTGPLLRTSIHQNSGGQKSQNTGLTTKKFYGNNVEKVPIDIIVNCDDSKHTYLQTNGKVILPGAKIPKITNLKERKTSLSDLNDPIILSSDDDDDNDRTNRRESISPQPADSACSSPAPSTGKVEAALNENTCRAERELRSIPEDSELNTVTLPRKARMKDQFGNSIINTPLKRRKVFSQEPPDALALSCQSSFDSVILNCRSIRVGTLFRLLIEPVIFCLDFIKIQLDEPDHDPVEIILNTSDLTKCEWCNVRKLPVVFLQAIPAVYQKLSIQLQMNKEDKVWNDCKGVNKLTNLEEQYIILIFQNGLDPPANMVFESIINEIGIKNNISNFFAKIPFEEANGRLVACTRTYEESIKGSCGQKENKIKTVSFESKIQLRSKQEFQFFDEEEETGENHTIFIGPVEKLIVYPPPPAKGGISVTNEDLHCLNEGEFLNDVIIDFYLKYLVLEKLKKEDADRIHIFSSFFYKRLNQRERRNHETTNLSIQQKRHGRVKTWTRHVDIFEKDFIFVPLNEAAHWFLAVVCFPGLEKPKYEPNPHYHENAVIQKCSTVEDSCISSSASEMESCSQNSSAKPVIKKMLNKKHCIAVIDSNPGQEESDPRYKRNICSVKYSVKKINHTASENEEFNKGESTSQKVADRTKSENGLQNESLSSTHHTDGLSKIRLNYSDESPEAGKMLEDELVDFSEDQDNQDDSSDDGFLADDNCSSEIGQWHLKPTICKQPCILLMDSLRGPSRSNVVKILREYLEVEWEVKKGSKRSFSKDVMKGSNPKVPQQNNFSDCGVYVLQYVESFFENPILSFELPMNLANWFPPPRMRTKREEIRNIILKLQEDQSKEKRKHKDTYSTEAPLGEGTEQYVNSISD", "length": 1112 }, "evidence": [ { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" }, { "id": "FB:FBgn0035713", "url": "https://alliancegenome.org/gene/FB:FBgn0035713#orthology", "database": "AGR" }, { "id": "HGNC:20944", "url": "https://alliancegenome.org/gene/HGNC:20944#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-25#orthology", "database": "AGR" }, { "id": "RGD:1304565", "url": "https://alliancegenome.org/gene/RGD:1304565#orthology", "database": "AGR" }, { "id": "MGI:1922075", "url": "https://alliancegenome.org/gene/MGI:1922075#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VRY4-1", "protein_name": "Veloren, isoform A", "gene_name": "velo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEQYIVPLEEPVYSDLQVVQVPQDEVGSLVLQDDQQLVFNDQQQVVYQTTAPAQYQQPQQSAAPTYHIIGGDDLAHQQQQHQQQQQQQQQQQQQQQQPQQQHQQQQQQVVMHHQQHQVQQVQQVHYQQQQQEPQQQQQQLHMEQQQQQQQQYVQHQPQQPAIQHTQQIYYTSEQVLQPNAIVQHMQQQKKQQQVLQQQQQQQQQYQQHAPAYQVQSSPQGQAQLLQSSQQQHQQAQQAQTLQLQTSPPQQQPQQHQQIVYRMTTTQQQQRPLGMLNNTHVIVQQQPVLIQGPQHQELIMRQAIHPYNNRVVYATSPQQQQQQQHVIQQHVQQQQVQQHQQVQQQQQMQLQPTTQTAHLVQARVVPQQTQNVVYQQLQVQKVQPQQQQQAPQQQQPQLVAQQQPQLVATSAAGGTQLVRASFRKSPRGGAVLARPGTLITTRPTLTPTTIVRQVRPRGGAVPGGLVRNMRPAGVRPTRAQLVVQTSASGEGQTMLVTQGQMKHITISTNLGQPQQQQQQQMQQQPRHIYRTHMVTDGNPQQQQQQAAQQQPQQHQQMLMMRHGPVRYRAPVSSAVAAPVQAPAPTAAGGGVQTSNIGMDLEERIEAAVLKKEQQKPQPTAQPVASNQLQPMQIGTGTTLTTYYPAGTASQEEEQQQQQQQQQQQQQQQQQVVQSQQQGIRPPSGASMTLAEYKKRQTLSASPAPVPPSNPGLAPMRATPPGTMVRPTAKITPTQHAGALPPGTRIMQPQRPVPAAVAAPIPAPAAVTQGSSVMKTSHNNYEIHSQHVLNNRAGQEIAERDKNSAKMLVILASGEQRLITFTLPRESCTVQDLLEQVGVPFDHNTTIQCVEHRGANVDFVVTVGFTVHESASELISRAEESLQMNRSQENQAAVAGAAAAANSNPATTSASPAYAQANAAAEQAKREAASSASGNTVVGTVSSAGSAGATPSEGRKLIDGFLAVCQLCGFTGVDHARCERCKRVFPEPPKRKSYVPKNSAASSPASSSSSEPVSAVPTAADKKRELAAARFNNKMAGANFAVGVGVRGRGSMAMRGGRARGGRRVPEVDPVVLLSSEDEAEGGEGTSDSSNQPTNNSKLNSNGNLHELSAAFPCEPNLPEIDEEPLYKDFSRGDVRDLSDIPEADQFSASLKCSCVRLVPYRFEITEPVCFTTKGVRIAGILKDKDEKFELNIHKQEVIKVIAHFGNVEPAQPLVTLYLLKTCAEYVKNQLKLPDDQHHEHTGFKTHSYHTRRLILLFDSISVSARGNIKSMFSCVDEISSTDAAEILERIADSDRKTQDKSSQPPPRQLRADEQVSLLMYPPKGTGGLCIRMEDFVCLTKESYLNDIIIDFYLLWLRNTLIPEPQRERTHIFSTFFYKRLTTLTRPADMKQTAAQKRHARVQKWTKGVDIFDKDFIIVPINEQSHWFLAIICYPNLKGPVTFDTNQPVEPQQLKRPRGKKVALQIGNTTITPLTKRAEGGQLPAALTAENVCRIADDESERDEAEGDESDMASEDSENSNSAKEPAATPTSTTASTPSLSSSQPTATGPARNIASDDVPAVKQPLILIFDSLAGASRSRVVATLRDYLTCEYRVKKPDAQAHVFNKDNMPGHCVKVPQQNNFTDCGLYLLQYVEQFFGEPIRDYRLPIKQLTNWFDFLTVTKKREDIANLIQQLMDEGNQQQRLILPVIEFPTLNGQLVEYPEDTESAEFEEEEGHDDEDPASEMHDENNAGTDMEVDPVNEEPALAGKTAALAPASTTAAAPTGKRFVLKRRLHNGAVSSPTNGNGEASSNGGALIPQLVSTAAATTTGVSSGVAHLGPRGPSGGLKIRKIEP", "length": 1833 }, "evidence": [ { "id": "FB:FBgn0035713", "url": "https://alliancegenome.org/gene/FB:FBgn0035713#orthology", "database": "AGR" }, { "id": "HGNC:20944", "url": "https://alliancegenome.org/gene/HGNC:20944#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-25#orthology", "database": "AGR" }, { "id": "RGD:1304565", "url": "https://alliancegenome.org/gene/RGD:1304565#orthology", "database": "AGR" }, { "id": "MGI:1922075", "url": "https://alliancegenome.org/gene/MGI:1922075#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VYJ5-1", "protein_name": "Pirate, isoform A", "gene_name": "pira", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDRKETVSKDQAVRRIAHNDFILVSRQLLINRADTDPDKGSARMLIIYSSGKQHIVTFKLPNLACRVQDLFFQMDLQIDESTTIDCIENAGGIIHLVVSVGFPISDNIAETVAHAEEFYRKVHQSKASSADAAPPNAMAGEEHSPAVVKPSETAVANNGCQPAASATKGKKHKKSPCGSPGENNDGQVILSADQDANTNTKAKKQKKCHIAKDNNGIQAASSHDNPSSSGNKQGSHNSTAITSNSTMTSNGLRGVQPAEDAPAISQWIQSRNNAAVSKKSEETAGGSQSRVQSNVASISSPAVKATSDAAIPTPAERAERSRLRRNRNWILSRDVDEDAVVLVSSGDEETTAADDGQTERRLSPDENQTLFTYPPTGTGGLSITIKDFMCLSKGSYLNDIIIDFYLRWLKNNIIPEEQRDRTHIFSTFFHKRLTTRTNPRNTKQTAAQKRHERVEKWTRNVNIFDKDFIIIPFNEQSHWILAIICYPNLRSPVVNNNNVQTTLSDDIPIKQPLILIFDSLAVTSRHRAIAILRDYLTCEHKAKYPNALAHVFNKDNMPGHSVEVPQQQNLTDCGLYLLQYVEQFFTKPINDYTLPIKELSNWFDLLTVTKKREDIANLIKKLMNESNQQRKILPVIKFPTLNGQLVMDEEDSEEENSKEEHKTTLVCSKDRKPPRRRNTLK", "length": 681 }, "evidence": [ { "id": "FB:FBgn0030420", "url": "https://alliancegenome.org/gene/FB:FBgn0030420#orthology", "database": "AGR" }, { "id": "HGNC:20944", "url": "https://alliancegenome.org/gene/HGNC:20944#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-25", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-25#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9" } ], "pmid": "" }, { "name": "regulation of spindle assembly", "id": "GO:0090169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090169", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9" } ], "pmid": "" }, { "name": "regulation of kinetochore assembly", "id": "GO:0090234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090234", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9" } ], "pmid": "" }, { "name": "protein desumoylation", "id": "GO:0016926", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016926", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "cysteine-type peptidase activity", "id": "GO:0008234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008234", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9" } ], "pmid": "" }, { "name": "SUMO-specific endopeptidase activity", "id": "GO:0070139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070139", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPP9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 331, "end_pos": 333, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" }, { "start_pos": 771, "end_pos": 773, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" }, { "start_pos": 948, "end_pos": 950, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PPP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPP9" }, { "id": "PS50600", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50600" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like protease family profile", "eco_id": "ECO_0000259", "start_pos": 675, "end_pos": 963, "start_aa": "Ile", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 278, 603 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 229, "end_pos": 231 }, { "start_pos": 331, "end_pos": 333 }, { "start_pos": 74, "end_pos": 76 }, { "start_pos": 771, "end_pos": 773 }, { "start_pos": 91, "end_pos": 93 }, { "start_pos": 948, "end_pos": 950 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PJP4-1", "uniprot_ac": "A0A8M9PJP4", "uniprot_id": "A0A8M9PJP4_DANRE", "mass": { "chemical_mass": 82049.0, "monoisotopic_mass": 82049.0 }, "refseq": { "ac": "XP_021325059", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325059" }, "gene_names": [ { "name": "LOC110438251", "type": "recommended", "evidence": [ { "id": "A0A8M9PJP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4" } ] }, { "name": "LOC110438251", "type": "synonym", "evidence": [ { "id": "XP_021325059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325059" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PJP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325059", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325059" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325059.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325059" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJP4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0AC58IFF9", "url": "https://www.uniprot.org/uniprotkb/A0AC58IFF9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJP4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438251", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4", "locus": {} } ], "crossref": [ { "id": "A0A8M9PJP4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PJP4", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438251", "url": "https://www.ncbi.nlm.nih.gov/gene/110438251", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110438251", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438251", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PJP4", "url": "https://www.orthodb.org/?gene=A0A8M9PJP4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF111", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF111", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF43", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF43", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13912", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13912", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325059", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325059", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PJP4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IFF9", "url": "https://www.uniprot.org/uniprotkb/A0AC58IFF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IFF9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IFF9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSISHTAPLTPWIKNPLVSLSLFKLFRSHEHPLTAIVFCPVRSILIWRVVVEPPLLPPRRDDVTAYAFIQRRVFRAELSERQRQSLLKDSVKMSDPEPCRIKQEDTEELIGVKVKEESEAPSEDEEKHHVKSEEETHTSTEHSVLLNSTAVNAFACTQCGKSFGRKYDLKRHMKIHTGGKVYKCSHCNKTFHKLVQLRAHKKIHAKEKLFLCIACGKRFRDLISLRRHTYKYHELSEDIETYLNVHSKMKLFSCSSCGKSFDSPHGLRKHQMIHTGEKLYKCSHCDKTFNDSGGLKAHEMIHTGERPYTCTQCGKSFTRLSSLKRHMMIHTGEKPHQCDQCGKTFSKPSELKYHLTVHQEEKPYSCSECGKSFKRKPGLRKHEKIHAGEKLFKCSHCDKKFCKRGQLRAHKKIHTKEKLFLCIACGKRFRDIFNLQRHTQKFHEINEDMKNYLSVHSKMKPFSCSLCGKSFKRPDSLRKHQMIHTGEKPYKCSHCDKTFSELRKQKTHERIHTGEKPYTCTQCGKSFRLSSSLNLHMMIHGGEKPYKCSHCDKTFNESGKLKAHERIHTGEKPYTCTQCWKSFRLSSSLNLHMMIHTGEKPHQCDQCGKGFPRPKELKRHLRVHTMKKPYSCSECGKSFTLQSSLKRHQKIHTGLREHVCFECGKSFTTAEHLIEHQRTHTGEKPDMECGKSFTQSSTFKEDMERK", "length": 706, "header": "tr|A0A8M9PJP4-1|A0A8M9PJP4_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110438251 PE=3 SV=2 CANONICAL=A0A8M9PJP4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PJP4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4/entry#A0A8M9PJP4-1", "sequence": { "sequence": "MSISHTAPLTPWIKNPLVSLSLFKLFRSHEHPLTAIVFCPVRSILIWRVVVEPPLLPPRRDDVTAYAFIQRRVFRAELSERQRQSLLKDSVKMSDPEPCRIKQEDTEELIGVKVKEESEAPSEDEEKHHVKSEEETHTSTEHSVLLNSTAVNAFACTQCGKSFGRKYDLKRHMKIHTGGKVYKCSHCNKTFHKLVQLRAHKKIHAKEKLFLCIACGKRFRDLISLRRHTYKYHELSEDIETYLNVHSKMKLFSCSSCGKSFDSPHGLRKHQMIHTGEKLYKCSHCDKTFNDSGGLKAHEMIHTGERPYTCTQCGKSFTRLSSLKRHMMIHTGEKPHQCDQCGKTFSKPSELKYHLTVHQEEKPYSCSECGKSFKRKPGLRKHEKIHAGEKLFKCSHCDKKFCKRGQLRAHKKIHTKEKLFLCIACGKRFRDIFNLQRHTQKFHEINEDMKNYLSVHSKMKPFSCSLCGKSFKRPDSLRKHQMIHTGEKPYKCSHCDKTFSELRKQKTHERIHTGEKPYTCTQCGKSFRLSSSLNLHMMIHGGEKPYKCSHCDKTFNESGKLKAHERIHTGEKPYTCTQCWKSFRLSSSLNLHMMIHTGEKPHQCDQCGKGFPRPKELKRHLRVHTMKKPYSCSECGKSFTLQSSLKRHQKIHTGLREHVCFECGKSFTTAEHLIEHQRTHTGEKPDMECGKSFTQSSTFKEDMERK", "length": 706, "header": "tr|A0A8M9PJP4-1|A0A8M9PJP4_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110438251 PE=3 SV=2 CANONICAL=A0A8M9PJP4-1" }, "locus": {} }, { "isoform_ac": "A0AC58IFF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4/entry#A0AC58IFF9-1", "sequence": { "sequence": "MSDPEPCRIKQEDTEELIGVKVKEESEAPSEDEEKHHVKSEEETHTSTEHSVLLNSTAVNAFACTQCGKSFGRKYDLKRHMKIHTGGKVYKCSHCNKTFHKLVQLRAHKKIHAKEKLFLCIACGKRFRDLISLRRHTYKYHELSEDIETYLNVHSKMKLFSCSSCGKSFDSPHGLRKHQMIHTGEKLYKCSHCDKTFNDSGGLKAHEMIHTGERPYTCTQCGKSFTRLSSLKRHMMIHTGEKPHQCDQCGKTFSKPSELKYHLTVHQEEKPYSCSECGKSFKRKPGLRKHEKIHAGEKLFKCSHCDKKFCKRGQLRAHKKIHTKEKLFLCIACGKRFRDIFNLQRHTQKFHEINEDMKNYLSVHSKMKPFSCSLCGKSFKRPDSLRKHQMIHTGEKPYKCSHCDKTFSELRKQKTHERIHTGEKPYTCTQCGKSFRLSSSLNLHMMIHGGEKPYKCSHCDKTFNESGKLKAHERIHTGEKPYTCTQCWKSFRLSSSLNLHMMIHTGEKPHQCDQCGKGFPRPKELKRHLRVHTMKKPYSCSECGKSFTLQSSLKRHQKIHTGLREHVCFECGKSFTTAEHLIEHQRTHTGEKPDMECGKSFTQSSTFKEDMERK", "length": 614, "header": "tr|A0AC58IFF9-1|A0AC58IFF9_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC110438251 PE=3 SV=1 CANONICAL=A0A8M9PJP4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110438251", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438251", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJP4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJP4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": 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"url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PJP4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJP4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 181, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 147, "end_pos": 149 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 556, "end_pos": 558 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PJQ5-1", "uniprot_ac": "A0A8M9PJQ5", "uniprot_id": "A0A8M9PJQ5_DANRE", "mass": { "chemical_mass": 101841.0, "monoisotopic_mass": 101841.0 }, "refseq": { "ac": "XP_021322461", "name": "regulator of G-protein signaling 22", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322461" }, "gene_names": [ { "name": "rgs22", "type": "recommended", "evidence": [ { "id": "A0A8M9PJQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJQ5" } ] }, { "name": "rgs22", "type": "synonym", "evidence": [ { "id": "XP_021322461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322461" } ] } ], "protein_names": [ { "name": "Regulator of G-protein signaling 22", "type": "synonym", "evidence": [ { "id": "A0A8M9PJQ5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJQ5/entry#names_and_taxonomy" } ] }, { "name": "regulator of G-protein signaling 22", "type": "synonym", "evidence": [ { "id": "XP_021322461", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322461" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322461.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322461", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322461" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJQ5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJQ5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rgs22", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJQ5", "locus": {} } ], "crossref": [ { "id": "A0A8M9PJQ5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PJQ5", "database": "AlphaFoldDB", "categories": [] }, { "id": "101884083", "url": "https://www.ncbi.nlm.nih.gov/gene/101884083", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016137", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016137", "database": 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This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021325094.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325094", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325094" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJS4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJS4#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJS4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJS4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC103909511", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJS4", "locus": {} } ], "crossref": [ { "id": "103909511", "url": 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"evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJS4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJS4" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJS4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJS4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJS4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJS4" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJS4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJS4" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJS4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJS4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 231, "end_pos": 233, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PJS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJS4" }, { "id": "PS50157", "database": 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"##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073805621", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073805621" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJU7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100330143", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7", "locus": {} } ], "crossref": [ { "id": "100330143", "url": "https://www.ncbi.nlm.nih.gov/gene/100330143", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100330143", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330143", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PJU7", "url": "https://www.orthodb.org/?gene=A0A8M9PJU7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46599", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46599", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46599:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46599:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13843", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073805621", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073805621", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PJU7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TMP0", "url": "https://www.uniprot.org/uniprotkb/A0AB32TMP0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TMP0-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TMP0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGJ9", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGL3", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGL3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGM1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGM3", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGM3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGM9", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGM9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGN2", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGN2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGN4", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGN4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGN5", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGN5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGN5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEYKSSKSKDRQSFNDGPKGKHKPKERKQVQVNVGVMVPHGTDLKPLRGKTLLLFTDPDVAAPDLLKQAVEKIGTFIMDMPEGPYVLLYHDCSEVVYVPGSERPFKLSEYKKEVGKPYARITFFICLEKHYKRVDDTSDSDSEIVITTRSTAKFNQADTLRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRRPSSDLYLPEEDYDSKDALQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISIVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSVKNKLLSNAPRGTMRWIRQDKLLFVEWKDSREVQMCSSFHKAYEGDTVQRKVRQDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCVTEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKENGKKPLTRKAFLQALILELTDIDSLDSAAVPLSLSSSG", "length": 728, "header": "tr|A0A8M9PJU7-1|A0A8M9PJU7_DANRE Isoform 1 of PiggyBac transposable element-derived protein 4 isoform X1 OS=Danio rerio OX=7955 GN=LOC100330143 PE=4 SV=2 CANONICAL=A0A8M9PJU7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PJU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7/entry#A0A8M9PJU7-1", "sequence": { "sequence": "MEYKSSKSKDRQSFNDGPKGKHKPKERKQVQVNVGVMVPHGTDLKPLRGKTLLLFTDPDVAAPDLLKQAVEKIGTFIMDMPEGPYVLLYHDCSEVVYVPGSERPFKLSEYKKEVGKPYARITFFICLEKHYKRVDDTSDSDSEIVITTRSTAKFNQADTLRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRRPSSDLYLPEEDYDSKDALQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISIVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSVKNKLLSNAPRGTMRWIRQDKLLFVEWKDSREVQMCSSFHKAYEGDTVQRKVRQDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCVTEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKENGKKPLTRKAFLQALILELTDIDSLDSAAVPLSLSSSG", "length": 728, "header": "tr|A0A8M9PJU7-1|A0A8M9PJU7_DANRE Isoform 1 of PiggyBac transposable element-derived protein 4 isoform X1 OS=Danio rerio OX=7955 GN=LOC100330143 PE=4 SV=2 CANONICAL=A0A8M9PJU7-1" }, "locus": {} }, { "isoform_ac": "A0AB32TMP0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7/entry#A0AB32TMP0-1", "sequence": { "sequence": "MDMPEGPYVLLYHDCSEVVYVPGSERPFKLSEYKKEVGKPYARITFFICLEKHYKRVDDTSDSDSEIVITTRSTAKFNQADTLRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRRPSSDLYLPEEDYDSKDALQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISIVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSVKNKLLSNAPRGTMRWIRQDKLLFVEWKDSREVQMCSSFHKAYEGDTVQRKVRQDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCVTEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKENGKKPLTRKAFLQALILELTDIDSLDSAAVPLSLSSSG", "length": 651, "header": "tr|A0AB32TMP0-1|A0AB32TMP0_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X5 OS=Danio rerio OX=7955 GN=LOC100330143 PE=4 SV=1 CANONICAL=A0A8M9PJU7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JGJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7/entry#A0AC58JGJ9-1", "sequence": { "sequence": "MEYKSSKSKDRQSFNDGPKGKHKPKERKQVQVNVGVMVPHGTDLKPLRGKTLLLFTDPDVAAPDLLKQAVEKIGTFIMDMPEGPYVLLYHDCSEVVYVPGSERPFKLSEYKKEVGKPYARITFFICLEKHYKRVDDTSDSDSEIVITTRSTAKFNQADTLRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRPSSDLYLPEEDYDSKDALQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISIVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSVKNKLLSNAPRGTMRWIRQDKLLFVEWKDSREVQMCSSFHKAYEGDTVQRKVRQDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCVTEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKENGKKPLTRKAFLQALILELTDIDSLDSAAVPLSLSSSG", "length": 727, "header": "tr|A0AC58JGJ9-1|A0AC58JGJ9_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X2 OS=Danio rerio OX=7955 GN=LOC100330143 PE=4 SV=1 CANONICAL=A0A8M9PJU7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JGL3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7/entry#A0AC58JGL3-1", "sequence": { "sequence": "MFIDDMDPILDRRPSSDLYLPEEDYDSKDALQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISIVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSVKNKLLSNAPRGTMRWIRQDKLLFVEWKDSREVQMCSSFHKAYEGDTVQRKVRQDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCVTEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKENGKKPLTRKAFLQALILELTDIDSLDSAAVPLSLSSSG", "length": 510, "header": "tr|A0AC58JGL3-1|A0AC58JGL3_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X8 OS=Danio rerio OX=7955 GN=LOC100330143 PE=4 SV=1 CANONICAL=A0A8M9PJU7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JGM1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7/entry#A0AC58JGM1-1", "sequence": { "sequence": "MFIDDMDPILDRRPSSDLYLPEEDYDSKDALQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISIVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSVKNKLLSNAPRGTMRWIRQDKLLFVEWKDSREVQMCSSFHKAYEGDTVQRKVRQDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCVTEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKENGHADSAAGRKCFLQSCVT", "length": 491, "header": "tr|A0AC58JGM1-1|A0AC58JGM1_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X9 OS=Danio rerio OX=7955 GN=LOC100330143 PE=4 SV=1 CANONICAL=A0A8M9PJU7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JGM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7/entry#A0AC58JGM3-1", "sequence": { "sequence": "MEYKSSKSKDRQSFNDGPKGKHKPKERKQVQVNVGVMVPHGTDLKPLRGKTLLLFTDPDVAAPDLLKQAVEKIGTFIMDMPEGPYVLLYHDCSEVVYVPGSERPFKLSEYKKEVGKPYARITFFICLEKHYKRVDDTSDSDSEIVITTRSTAKFNQADTLRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRPSSDLYLPEEDYDSKDALQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISIVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSVKNKLLSNAPRGTMRWIRQDKLLFVEWKDSREVQMCSSFHKAYEGDTVQRKVRQDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCVTEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKENGHADSAAGRKCFLQSCVT", "length": 708, "header": "tr|A0AC58JGM3-1|A0AC58JGM3_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X4 OS=Danio rerio OX=7955 GN=LOC100330143 PE=4 SV=1 CANONICAL=A0A8M9PJU7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JGM9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7/entry#A0AC58JGM9-1", "sequence": { "sequence": "MEYKSSKSKDRQSFNDGPKGKHKPKERKQVQVNVGVMVPHGTDLKPLRGKTLLLFTDPDVAAPDLLKQAVEKIGTFIMDMPEGPYVLLYHDCSEVVYVPGSERPFKLSEYKKEVGKPYARITFFICLEKHYKRVDDTSDSDSEIVITTRSTAKFNQADTLRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRRPSSDLYLPEEDYDSKDALQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISIVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSVKNKLLSNAPRGTMRWIRQDKLLFVEWKDSREVQMCSSFHKAYEGDTVQRKVRQDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCVTEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKENGHADSAAGRKCFLQSCVT", "length": 709, "header": "tr|A0AC58JGM9-1|A0AC58JGM9_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X3 OS=Danio rerio OX=7955 GN=LOC100330143 PE=4 SV=1 CANONICAL=A0A8M9PJU7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JGN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7/entry#A0AC58JGN2-1", "sequence": { "sequence": "MDMPEGPYVLLYHDCSEVVYVPGSERPFKLSEYKKEVGKPYARITFFICLEKHYKRVDDTSDSDSEIVITTRSTAKFNQADTLRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRPSSDLYLPEEDYDSKDALQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISIVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSVKNKLLSNAPRGTMRWIRQDKLLFVEWKDSREVQMCSSFHKAYEGDTVQRKVRQDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCVTEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKENGKKPLTRKAFLQALILELTDIDSLDSAAVPLSLSSSG", "length": 650, "header": "tr|A0AC58JGN2-1|A0AC58JGN2_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X6 OS=Danio rerio OX=7955 GN=LOC100330143 PE=4 SV=1 CANONICAL=A0A8M9PJU7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JGN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7/entry#A0AC58JGN4-1", "sequence": { "sequence": "MFIDDMDPILDRPSSDLYLPEEDYDSKDALQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISIVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSVKNKLLSNAPRGTMRWIRQDKLLFVEWKDSREVQMCSSFHKAYEGDTVQRKVRQDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCVTEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKENGHADSAAGRKCFLQSCVT", "length": 490, "header": "tr|A0AC58JGN4-1|A0AC58JGN4_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X10 OS=Danio rerio OX=7955 GN=LOC100330143 PE=4 SV=1 CANONICAL=A0A8M9PJU7-1" }, "locus": {} }, { "isoform_ac": "A0AC58JGN5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7/entry#A0AC58JGN5-1", "sequence": { "sequence": "MDMPEGPYVLLYHDCSEVVYVPGSERPFKLSEYKKEVGKPYARITFFICLEKHYKRVDDTSDSDSEIVITTRSTAKFNQADTLRKLVPVVPAVAVEGFHASASVPKKNTTNNADCIVGSDEELDFCDQDSVASSVDSSAEDMFIDDMDPILDRRPSSDLYLPEEDYDSKDALQHRKRLCLSSAEGGDRKSENGFYWTETEKWQSSDEADVEPPLLVFTPNQNPGPQILPNRCSSALQFFQLLFPKSMFQTIAGYTNSYAAKYEERKGKLWNFISQSDMKSYVALVIYMGMFRCSSLSDYWSESQHFSLSFPAKIMSYRKFLSISIVLHLSESREDEKNILKKGTAGYERLGKIQPLYQVIRESCKSYFHPFQNITIVERMVKPQAGTGLKQSLKSRSPNMGFKLFALTDCTCGYTWDFFVYEGKSCASRSEGLSYETVMALVDENMLGSGYKLFVDKFYTSPTLFTDLLDKKVLACGPVWPNRTGYPKSVKNKLLSNAPRGTMRWIRQDKLLFVEWKDSREVQMCSSFHKAYEGDTVQRKVRQDAHRTLEEIPVPAVVLDYSKNMEAVDSSDCVTEHFRAIHKPKKWYQCMFYHFLDIAVENAFIMQELVTKENGHADSAAGRKCFLQSCVT", "length": 632, "header": "tr|A0AC58JGN5-1|A0AC58JGN5_DANRE Computationally mapped isoform of PiggyBac transposable element-derived protein 4 isoform X7 OS=Danio rerio OX=7955 GN=LOC100330143 PE=4 SV=1 CANONICAL=A0A8M9PJU7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100330143", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330143", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 450, "end_pos": 452, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PJU7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJU7" }, { "id": "PF13843", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13843" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PiggyBac transposable element-derived protein", "eco_id": "ECO_0000259", "start_pos": 312, "end_pos": 681, "start_aa": "Ala", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 185, "end_pos": 187 }, { "start_pos": 450, "end_pos": 452 }, { "start_pos": 559, "end_pos": 561 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PJV4-1", "uniprot_ac": "A0A8M9PJV4", "uniprot_id": "A0A8M9PJV4_DANRE", "mass": { "chemical_mass": 46543.0, "monoisotopic_mass": 46543.0 }, "refseq": { "ac": "XP_021327253", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327253" }, "gene_names": [ { "name": "LOC100151089", "type": "recommended", "evidence": [ { "id": "A0A8M9PJV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV4" } ] }, { "name": "LOC100151089", "type": "synonym", "evidence": [ { "id": "XP_021327253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327253" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PJV4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021327253", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327253" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021327253.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021327253", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327253" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJV4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100151089", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV4", "locus": {} } ], "crossref": [ { "id": "A0A8M9PJV4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PJV4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100151089", "url": "https://www.ncbi.nlm.nih.gov/gene/100151089", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100151089", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100151089", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_021327253", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327253", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PJV4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSLFRRGFWPLSAGFTPIWGRRLSPQKAEISAEAGESKAKSTKKHRKVKSHHGQRPRKEEKGLKVKAEDENIQILEREGGKGEPEGQRRNLKNNKTLPLPIEVKPLPASACFSSLPPVGDQPEHSDVLALPAACLKPLLINKEPLPHLVEVKPLPASACFSSLAPVGDLPEHPEVLVLPASRLKASSPQTPAEEPEHLLPSSVIQVAPCVSPEPVLLPLQSSSEVASLHSIPSVSELSFLQSPPETLPIPPIFAFDEVVSLVKPQASEFSPCSGLMLFDFEDEELEFMEYTEESIEASHESEMKPRRMEAWLEQEEVTEVQKHEEKGASQVIQNPLNEVSGDEAYTEIKTKKPKIYNPLVLFSLMEEKVKKKQEKKQRKEEEQIERNLLLKRYRNDPKLKHLRINKHNPNFCWS", "length": 414, "header": "tr|A0A8M9PJV4-1|A0A8M9PJV4_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100151089 PE=4 SV=2 CANONICAL=A0A8M9PJV4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PJV4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJV4/entry#A0A8M9PJV4-1", "sequence": { "sequence": "MSLFRRGFWPLSAGFTPIWGRRLSPQKAEISAEAGESKAKSTKKHRKVKSHHGQRPRKEEKGLKVKAEDENIQILEREGGKGEPEGQRRNLKNNKTLPLPIEVKPLPASACFSSLPPVGDQPEHSDVLALPAACLKPLLINKEPLPHLVEVKPLPASACFSSLAPVGDLPEHPEVLVLPASRLKASSPQTPAEEPEHLLPSSVIQVAPCVSPEPVLLPLQSSSEVASLHSIPSVSELSFLQSPPETLPIPPIFAFDEVVSLVKPQASEFSPCSGLMLFDFEDEELEFMEYTEESIEASHESEMKPRRMEAWLEQEEVTEVQKHEEKGASQVIQNPLNEVSGDEAYTEIKTKKPKIYNPLVLFSLMEEKVKKKQEKKQRKEEEQIERNLLLKRYRNDPKLKHLRINKHNPNFCWS", "length": 414, "header": "tr|A0A8M9PJV4-1|A0A8M9PJV4_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100151089 PE=4 SV=2 CANONICAL=A0A8M9PJV4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100151089", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100151089", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PJY6-1", "uniprot_ac": "A0A8M9PJY6", "uniprot_id": "A0A8M9PJY6_DANRE", "mass": { "chemical_mass": 73747.0, "monoisotopic_mass": 73747.0 }, "refseq": { "ac": "XP_021322545", "name": "protein shisa-7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322545" }, "gene_names": [ { "name": "shisa7a", "type": "recommended", "evidence": [ { "id": "A0A8M9PJY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6" } ] }, { "name": "shisa7a", "type": "synonym", "evidence": [ { "id": "XP_021322545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322545" } ] } ], "protein_names": [ { "name": "Protein shisa-7", "type": "synonym", "evidence": [ { "id": "A0A8M9PJY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6/entry#names_and_taxonomy" } ] }, { "name": "protein shisa-7", "type": "synonym", "evidence": [ { "id": "XP_021322545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322545" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322545.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322545" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJY6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "shisa7a", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100922-37", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100922-37", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "101883130", "url": "https://www.ncbi.nlm.nih.gov/gene/101883130", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026910", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026910", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053891", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053891", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101883130", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101883130", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PJY6", "url": "https://www.orthodb.org/?gene=A0A8M9PJY6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31774", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31774", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31774:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31774:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13908", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322545", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322545", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PJY6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PJY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100922-37", "url": "https://zfin.org/ZDB-GENE-100922-37", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMPTLEARVRVIILFLLIAVPLNASAASVPGPSRNGPITITPTPNPRSQGRSFMYPLAKNSGSMRGKSMNRRPKQPAGVAEMPLRPLPQIMLPKNVTTDKLKAPFGAAQVAPPPRKLVEVDVCRGYYDVMGQYDLTFNCSKDDFIYCCGTCHYRFCCPDRSRRLDQSICHNYQSPVWANTAPPVTRSPAPGLPDQSRIEQSNNTVYVIGGVISFTVAVAVAIKVAFHKASRQPRNRELNMPRALVEMLRHQSSPVQEGERNNSVALGTGGGEGTLGRPPKNLYPTLQKDNRLGNLQHNFIHTTGSSPKHTATIERAPRMNNMQLAMGGTLKPSKHTNAMKPQPSFHQSLHNLAQLPPSYEAAMKPEINRYSSLKRLEKGGLEEYSGYCTTKRRPNNARPDFHSSQHHLPWGGDYTLGGRGTLPTHAPRPRIPHPQSAPSHTPNPYPLDPPESKKNPNYDTLSKPPRRVKSTDQLLALADGSTLSRVPKNQQHQYYKGTSSKNSNNQNTLKKSKERLLMSPEHLEEEIGGVDYDGSTMGMGMSDYQGGGGGGMVPTLPRVSHQKAQSQQNVCATPSLDRHHMIKMNSHPTSGREQERNSAAMSGHLGGGGAGGVGWGDMPGTGVVMGTGTLGGHSARRLAFAAKRQNTIEQLHFIPGGGGSGGVASNQGVRTGSKNEVTV", "length": 679, "header": "tr|A0A8M9PJY6-1|A0A8M9PJY6_DANRE Isoform 1 of Protein shisa-7 OS=Danio rerio OX=7955 GN=shisa7a PE=4 SV=2 CANONICAL=A0A8M9PJY6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PJY6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6/entry#A0A8M9PJY6-1", "sequence": { "sequence": "MMPTLEARVRVIILFLLIAVPLNASAASVPGPSRNGPITITPTPNPRSQGRSFMYPLAKNSGSMRGKSMNRRPKQPAGVAEMPLRPLPQIMLPKNVTTDKLKAPFGAAQVAPPPRKLVEVDVCRGYYDVMGQYDLTFNCSKDDFIYCCGTCHYRFCCPDRSRRLDQSICHNYQSPVWANTAPPVTRSPAPGLPDQSRIEQSNNTVYVIGGVISFTVAVAVAIKVAFHKASRQPRNRELNMPRALVEMLRHQSSPVQEGERNNSVALGTGGGEGTLGRPPKNLYPTLQKDNRLGNLQHNFIHTTGSSPKHTATIERAPRMNNMQLAMGGTLKPSKHTNAMKPQPSFHQSLHNLAQLPPSYEAAMKPEINRYSSLKRLEKGGLEEYSGYCTTKRRPNNARPDFHSSQHHLPWGGDYTLGGRGTLPTHAPRPRIPHPQSAPSHTPNPYPLDPPESKKNPNYDTLSKPPRRVKSTDQLLALADGSTLSRVPKNQQHQYYKGTSSKNSNNQNTLKKSKERLLMSPEHLEEEIGGVDYDGSTMGMGMSDYQGGGGGGMVPTLPRVSHQKAQSQQNVCATPSLDRHHMIKMNSHPTSGREQERNSAAMSGHLGGGGAGGVGWGDMPGTGVVMGTGTLGGHSARRLAFAAKRQNTIEQLHFIPGGGGSGGVASNQGVRTGSKNEVTV", "length": 679, "header": "tr|A0A8M9PJY6-1|A0A8M9PJY6_DANRE Isoform 1 of Protein shisa-7 OS=Danio rerio OX=7955 GN=shisa7a PE=4 SV=2 CANONICAL=A0A8M9PJY6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 573, "start_aa": "Thr", "end_pos": 573, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr573", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101883130", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101883130", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "gamma-aminobutyric acid receptor clustering", "id": "GO:0097112", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097112", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJY6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6" } ], "pmid": "" }, { "name": "gamma-aminobutyric acid signaling pathway", "id": "GO:0007214", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007214", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJY6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJY6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6" } ], "pmid": "" }, { "name": "postsynaptic membrane", "id": "GO:0045211", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045211", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJY6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6" } ], "pmid": "" }, { "name": "dendritic spine membrane", "id": "GO:0032591", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032591", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJY6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GABA receptor binding", "id": "GO:0050811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050811", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PJY6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 23, "end_pos": 25, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 95, "end_pos": 97, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PJY6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PJY6" }, { "id": "PF13908", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13908" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Shisa N-terminal", "eco_id": "ECO_0000259", "start_pos": 121, "end_pos": 171, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 573 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 }, { "start_pos": 202, "end_pos": 204 }, { "start_pos": 23, "end_pos": 25 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 95, "end_pos": 97 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PK08-1", "uniprot_ac": "A0A8M9PK08", "uniprot_id": "A0A8M9PK08_DANRE", "mass": { "chemical_mass": 93693.0, "monoisotopic_mass": 93693.0 }, "refseq": { "ac": "XP_021322571", "name": "leucine-rich repeat-containing protein 53 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322571" }, "gene_names": [ { "name": "lrrc53", "type": "recommended", "evidence": [ { "id": "A0A8M9PK08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK08" } ] }, { "name": "lrrc53", "type": "synonym", "evidence": [ { "id": "XP_021322571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322571" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 53 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PK08", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK08/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 53 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322571", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322571" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322571", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322571" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK08", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK08" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "lrrc53", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK08", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131121-432", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-432", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PK08", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PK08", "database": "AlphaFoldDB", "categories": [] }, { "id": "101882576", "url": "https://www.ncbi.nlm.nih.gov/gene/101882576", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101882576", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882576", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PK08", "url": "https://www.orthodb.org/?gene=A0A8M9PK08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24366:SF96", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24366:SF96", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322571", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322571", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PK08", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PK08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HBV6", "url": "https://www.uniprot.org/uniprotkb/A0AC58HBV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HBV6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HBV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131121-432", "url": "https://zfin.org/ZDB-GENE-131121-432", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MISVCFLLMVTISQVDLALLCPSSCLVCSEDVTICQKLRSIIDAPGSTKALMLTDGLIDSVGSMVFSDLSNMSVLALSNNAISSITENAFQNLTFLTTLSLDHNHISNQALNSSTFSWLHRLETLQLSNNHLKDIDGSWFQSSIALKTLQLDGNLLTSLNSTTFAHADLRNLEILDLSDNLIVTLGRESFRRLPSLRRLDLSRNNLSSAPDAFSYLSWLSTLNLDLNRWSCSCELRELASFLNSFIQAPENVLYNGQKMACVNADNPSVQTVLQLTDANCVPPNSNITVEVVAKRSNTSQQYIRNVAIAVVFSFLGGVGITLGIIAIAYHKLSKKFKLMQEEHGASERITSSPEMAQWNFCEGKDTLSMSHALYNSNYKSHQPWDREDSPYGSDELENHFTCHKCSSTALTGGKPKRETVLQKTTENLQKNHMSEHLAHRQHNGNQQHSVLQQRIKDMHLKRQAERDSKSHLASQDFTSQRRGGPDDISAVRIQQLALSNHFSALQRGPFRPPNHIYNEETQANHSLLKHQASETTPRPIYQTISCLHCHQTYEYRQAQSNNHDFPFTNHSQNRGQMYDAMLYRDILGYEKRDADGCDESELGFKLASQRSVTFDLTMPEERTADRRNNQTSLQKSQRKSSAQKPHKSRGQTKKTLRVKLNLDPLRKNRVHPKSKSEDSKADDKKRKEKLRSKKKTCKKSKEDSVGNEETLNKRDAQMRVSKSVPEETEQNSTPAEGETQTSDAVFSSISEAQTPSVLTISPPDDASDAQPISNAALPVVESASGDMLDQSSSSDLTSSAAPLIQEYVSSSEGSFKIRLILPEKSSNRPQTALDKKIR", "length": 838, "header": "tr|A0A8M9PK08-1|A0A8M9PK08_DANRE Isoform 1 of Leucine-rich repeat-containing protein 53 isoform X1 OS=Danio rerio OX=7955 GN=lrrc53 PE=4 SV=1 CANONICAL=A0A8M9PK08-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PK08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK08/entry#A0A8M9PK08-1", "sequence": { "sequence": "MISVCFLLMVTISQVDLALLCPSSCLVCSEDVTICQKLRSIIDAPGSTKALMLTDGLIDSVGSMVFSDLSNMSVLALSNNAISSITENAFQNLTFLTTLSLDHNHISNQALNSSTFSWLHRLETLQLSNNHLKDIDGSWFQSSIALKTLQLDGNLLTSLNSTTFAHADLRNLEILDLSDNLIVTLGRESFRRLPSLRRLDLSRNNLSSAPDAFSYLSWLSTLNLDLNRWSCSCELRELASFLNSFIQAPENVLYNGQKMACVNADNPSVQTVLQLTDANCVPPNSNITVEVVAKRSNTSQQYIRNVAIAVVFSFLGGVGITLGIIAIAYHKLSKKFKLMQEEHGASERITSSPEMAQWNFCEGKDTLSMSHALYNSNYKSHQPWDREDSPYGSDELENHFTCHKCSSTALTGGKPKRETVLQKTTENLQKNHMSEHLAHRQHNGNQQHSVLQQRIKDMHLKRQAERDSKSHLASQDFTSQRRGGPDDISAVRIQQLALSNHFSALQRGPFRPPNHIYNEETQANHSLLKHQASETTPRPIYQTISCLHCHQTYEYRQAQSNNHDFPFTNHSQNRGQMYDAMLYRDILGYEKRDADGCDESELGFKLASQRSVTFDLTMPEERTADRRNNQTSLQKSQRKSSAQKPHKSRGQTKKTLRVKLNLDPLRKNRVHPKSKSEDSKADDKKRKEKLRSKKKTCKKSKEDSVGNEETLNKRDAQMRVSKSVPEETEQNSTPAEGETQTSDAVFSSISEAQTPSVLTISPPDDASDAQPISNAALPVVESASGDMLDQSSSSDLTSSAAPLIQEYVSSSEGSFKIRLILPEKSSNRPQTALDKKIR", "length": 838, "header": "tr|A0A8M9PK08-1|A0A8M9PK08_DANRE Isoform 1 of Leucine-rich repeat-containing protein 53 isoform X1 OS=Danio rerio OX=7955 GN=lrrc53 PE=4 SV=1 CANONICAL=A0A8M9PK08-1" }, "locus": {} }, { "isoform_ac": "A0AC58HBV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK08/entry#A0AC58HBV6-1", "sequence": { "sequence": "MLQLCFIVGGVGITLGIIAIAYHKLSKKFKLMQEEHGASERITSSPEMAQWNFCEGKDTLSMSHALYNSNYKSHQPWDREDSPYGSDELENHFTCHKCSSTALTGGKPKRETVLQKTTENLQKNHMSEHLAHRQHNGNQQHSVLQQRIKDMHLKRQAERDSKSHLASQDFTSQRRGGPDDISAVRIQQLALSNHFSALQRGPFRPPNHIYNEETQANHSLLKHQASETTPRPIYQTISCLHCHQTYEYRQAQSNNHDFPFTNHSQNRGQMYDAMLYRDILGYEKRDADGCDESELGFKLASQRSVTFDLTMPEERTADRRNNQTSLQKSQRKSSAQKPHKSRGQTKKTLRVKLNLDPLRKNRVHPKSKSEDSKADDKKRKEKLRSKKKTCKKSKEDSVGNEETLNKRDAQMRVSKSVPEETEQNSTPAEGETQTSDAVFSSISEAQTPSVLTISPPDDASDAQPISNAALPVVESASGDMLDQSSSSDLTSSAAPLIQEYVSSSEGSFKIRLILPEKSSNRPQTALDKKIR", "length": 531, "header": "tr|A0AC58HBV6-1|A0AC58HBV6_DANRE Computationally mapped isoform of Leucine-rich repeat-containing protein 53 isoform X2 OS=Danio rerio OX=7955 GN=lrrc53 PE=4 SV=1 CANONICAL=A0A8M9PK08-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101882576", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882576", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AMC2-1", "protein_name": "Leucine rich repeat containing 53", "gene_name": "Lrrc53", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLYVTVACPASCVACTQDVTLCHQLNHIVAAPETTKVLILTDGDLSSVERTNLTLQVNLALLSLSRNAIYRIQVGSLHGLTKLRTSSLGHNHIPSSSLSDHTFSKQRSLQVLVLNHNSLRSLRAAWFRNKALSRLFSFKGANLHRLRHLDLSNDFISFIEKDAFQPLPQLQEVDLSRNMLAHTPDAFTPLKQLSPLSLEGNHWSCTCDLYQLARFLRKFVKSPARTLRNTKDPNCEVFPAAVATAKSMLRLSETNCDSKGHNVTLALKDRRPLLPGQDVALITVLGFAGAIGLTCAGLVIFNWKLQQGRANERTSKNLSCRTLNESPCAHEARNGRAVGYCNCHLTRENETQVMSDVGSRKEAPLRQENSHQARLAPKSTAVDVSFRKLKGRDHEAHSACSCLADELRAGCLGPPGNKKALYDADLATRCCPKTAEKPSNQKRGEIRSQILPQHGTKTIDVSSDTFRSRYATSSSALARESVGKHLMNESCLPFMEQHCLPH", "length": 502 }, "evidence": [ { "id": "RGD:7683241", "url": "https://alliancegenome.org/gene/RGD:7683241#orthology", "database": "AGR" }, { "id": "HGNC:25255", "url": "https://alliancegenome.org/gene/HGNC:25255#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-432", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-432#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6NM62-1", "protein_name": "Leucine-rich repeat-containing protein 53", "gene_name": "LRRC53", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRLVAACPESCVVCTKDVTLCHQLTYIVAAPMTTRVLIITDGYLSSIESTNLSLLFNLALLSLSRNGIEDVQEDALHGLTMLRTLLLEHNQISSSSLTDHTFSKLHSLQVLVLSNNALRTLRGSWFRNTSGLTRLQLDGNQITNLTDSSFGGTNLHSLRYLDLSNNFISYIGKDAFRPLPQLQEVDLSRNRLAHMPDVFTPLKQLILLSLDKNQWSCTCDLHPLARFLRNYIKSSAHTLRNAKDLNCQPSTAAVAAAQSVLRLSETNCDSKAPNFTLVLKDRSPLLPGPDVALLTVLGFAGAVGLTCLGLVVFNWKLHQGKANEHTSENLCCRTFDEPLCAHEARNYHTKGYCNCHLTQENEIKVMSTVGSRKEMPLLQENSHQATSASESATLDGSFRNLKKKDRGVGSTLFCQDGRLLHSECSEPPGNMRAFNEAGLLTTYNPRKVQKLWNLEPGEVQPQTLQHHIIRTEDISSDIFRRRYATPASALAGESLEKRLTNESWQPPIEKEDNGLHPHRQRHFITSSSSKPCEPEEHYVQKIVQKNRSKYDDPCGLLKQSKPRYFQPNNSLICKYVPCEQFEDYMKEKKPNRRQHSKPEKEQIQINSAIEKFLMSEDNIDLSGLSTKTKKAYSPKRVIFHDPDLVEINRSMMSPKISTPWKRQKNQSNQLTKLDVKKFSNTGERNKGEKWFTNSWVLKRKRTPQSDLKGKIKGQNLKLNLHPFRKVRVHPEKSLSSLPKQCKQVLLPPKKLSKTSETEAKINTVCSADFLQQSESSNYVRLTSKRLPLKHDSKQTPYYQRNTKRAPLLSANNLRVVNQSSIESSCYSAGHIPDGNTSKLPQPTPTDAEHRHSHSQFSTEQMEDATQLESKVLSYLATTWENTGSDVLPFQHSRRATDQGTTESTEHMGQNVSKTSELNQFSLSPRNQTQLLDAHKTDSYNKEYTLDQNEALQHREQNSSHAQLENKEKTLMTKPQISHQIVENCIMDKEENDVEKKLSKTETYDSSLIPQTQSKNNLSFMKTNSIPYQNRIELPKDISTSPVSSQAVWHLTNSSEKGIDSTNALPRNDGTEALEIKIVGKEEKNMLDESKTDSSMLTQISQMTLKGITKERQQTWENGTSEKYILHDASSAEETITAKDLSITSSHETQNRILCSEVDPEVNSNVHNFREVQNIQPDKDSAHKEGAMTVETHEALSFLPGLKDSFEAENEVFLVPSRINEAENSAPKPVLYPPSAEYATTSPLETE", "length": 1247 }, "evidence": [ { "id": "RGD:7683241", "url": "https://alliancegenome.org/gene/RGD:7683241#orthology", "database": "AGR" }, { "id": "HGNC:25255", "url": "https://alliancegenome.org/gene/HGNC:25255#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-432", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-432#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK08", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK08" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 286, "end_pos": 288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 569, "end_pos": 571, "annotation": "n_glycosylation_sequon" }, { "start_pos": 629, "end_pos": 631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" }, { "start_pos": 731, "end_pos": 733, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 160, "end_pos": 162 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 286, "end_pos": 288 }, { "start_pos": 297, "end_pos": 299 }, { "start_pos": 524, "end_pos": 526 }, { "start_pos": 569, "end_pos": 571 }, { "start_pos": 629, "end_pos": 631 }, { "start_pos": 71, "end_pos": 73 }, { "start_pos": 731, "end_pos": 733 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PK25-1", "uniprot_ac": "A0A8M9PK25", "uniprot_id": "A0A8M9PK25_DANRE", "mass": { "chemical_mass": 73707.0, "monoisotopic_mass": 73707.0 }, "refseq": { "ac": "XP_068070232", "name": "interferon-inducible GTPase 5-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070232" }, "gene_names": [ { "name": "LOC100333218", "type": "recommended", "evidence": [ { "id": "A0A8M9PK25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK25" } ] }, { "name": "LOC100333218", "type": "synonym", "evidence": [ { "id": "XP_068070232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070232" } ] } ], "protein_names": [ { "name": "Interferon-inducible GTPase 5-like", "type": "synonym", "evidence": [ { "id": "A0A8M9PK25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK25/entry#names_and_taxonomy" } ] }, { "name": "interferon-inducible GTPase 5-like", "type": "synonym", "evidence": [ { "id": "XP_068070232", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070232" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068070232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070232" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK25", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK25" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100333218", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK25", "locus": {} } ], "crossref": [ { "id": "100333218", "url": "https://www.ncbi.nlm.nih.gov/gene/100333218", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051515", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051515", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100333218", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333218", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PK25", "url": "https://www.orthodb.org/?gene=A0A8M9PK25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR32341", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32341", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR32341:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR32341:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_068070232", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070232", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PK25", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PK25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK25-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENPQQKAKQSSLVLESKLDELKKRERQREMNENNKEKQPEKETINVANEKERSEDAKVSNVDMKHKKKCLEEQNKQTKEPTKYYSSYPINEMKLIKKNNKLMNMQIQECNVDMIQKEKYIEKLNKQFKAGDSSDVNTKHKHKAAKKEEEGEKINIPIQITNDDENRLIRQKGEKATEILKTKPEGNGKGHLQHLYDAIMDKDVLTEEPTQSNSSEPIKLKENYGELMKMQKQELSNSRKPQDTHSHSTAKENVSLKSASTVQVEHIYEMPDVHLNSSAEYINEMECVIEQNKQLGNVTLHVAVTGSTGAGKSSFINAVRGLTSDDENAAPTGVTETTLVPMMYKHPTMPNVELWDLPGTGSPKFKAKKYLKEVKLETFDFFIIISSERFKENDIMLANAIKERKKLFYFLRSKIDNDIHAESHRKDFDEQKVLSHIREDCHRNLKDMDDPHVFLICSFELHKYDFQTFVDTLEKQLPDHKRDALILSLPIYSSKILEEKIEIFMKQTWSAAVASGSVAVVPVPGLSMACDAAILLGFFIKCYYAFGLDEKSIDKLSVRVNNPSLKAIRRSPLVVAIGQKKLTNKELSALTSKEAAVKFAWSMVPVVGSKKTAQMSYSTTLKLLRTGVQDLAETAREVLKAAGVTGVY", "length": 648, "header": "tr|A0A8M9PK25-1|A0A8M9PK25_DANRE Isoform 1 of Interferon-inducible GTPase 5-like OS=Danio rerio OX=7955 GN=LOC100333218 PE=3 SV=1 CANONICAL=A0A8M9PK25-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PK25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK25/entry#A0A8M9PK25-1", "sequence": { "sequence": "MENPQQKAKQSSLVLESKLDELKKRERQREMNENNKEKQPEKETINVANEKERSEDAKVSNVDMKHKKKCLEEQNKQTKEPTKYYSSYPINEMKLIKKNNKLMNMQIQECNVDMIQKEKYIEKLNKQFKAGDSSDVNTKHKHKAAKKEEEGEKINIPIQITNDDENRLIRQKGEKATEILKTKPEGNGKGHLQHLYDAIMDKDVLTEEPTQSNSSEPIKLKENYGELMKMQKQELSNSRKPQDTHSHSTAKENVSLKSASTVQVEHIYEMPDVHLNSSAEYINEMECVIEQNKQLGNVTLHVAVTGSTGAGKSSFINAVRGLTSDDENAAPTGVTETTLVPMMYKHPTMPNVELWDLPGTGSPKFKAKKYLKEVKLETFDFFIIISSERFKENDIMLANAIKERKKLFYFLRSKIDNDIHAESHRKDFDEQKVLSHIREDCHRNLKDMDDPHVFLICSFELHKYDFQTFVDTLEKQLPDHKRDALILSLPIYSSKILEEKIEIFMKQTWSAAVASGSVAVVPVPGLSMACDAAILLGFFIKCYYAFGLDEKSIDKLSVRVNNPSLKAIRRSPLVVAIGQKKLTNKELSALTSKEAAVKFAWSMVPVVGSKKTAQMSYSTTLKLLRTGVQDLAETAREVLKAAGVTGVY", "length": 648, "header": "tr|A0A8M9PK25-1|A0A8M9PK25_DANRE Isoform 1 of Interferon-inducible GTPase 5-like OS=Danio rerio OX=7955 GN=LOC100333218 PE=3 SV=1 CANONICAL=A0A8M9PK25-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100333218", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333218", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK25", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK25" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK25", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK25" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK25", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK25" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 297, "end_pos": 299, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PK25", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK25" }, { "id": "PS51716", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51716" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IRG-type G", "eco_id": "ECO_0000259", "start_pos": 298, "end_pos": 476, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": 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"evidence": [ { "id": "XP_021322601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322601" } ] } ], "protein_names": [ { "name": "G-protein coupled receptor 20", "type": "recommended", "evidence": [ { "id": "A0A8M9PK33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK33/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 20", "type": "synonym", "evidence": [ { "id": "XP_021322601", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322601" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322601", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322601" } ] }, { "annotation": "Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK33", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK33#function" }, { "database": "UniProtKB", "id": "ARBA00057030", "url": "https://www.uniprot.org/uniprotkb/ARBA00057030#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK33", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK33" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gpr20", "url": 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"table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PK34-1", "uniprot_ac": "A0A8M9PK34", "uniprot_id": "A0A8M9PK34_DANRE", "mass": { "chemical_mass": 104372.0, "monoisotopic_mass": 104372.0 }, "refseq": { "ac": "XP_021325224", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325224" }, "gene_names": [ { "name": "LOC103908669", "type": "recommended", "evidence": [ { "id": "A0A8M9PK34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK34" } ] }, { "name": "LOC103908669", "type": "synonym", "evidence": [ { "id": "XP_021325224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325224" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PK34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK34/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325224", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325224" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325224" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK34", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK34" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC103908669", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK34", "locus": {} } ], "crossref": [ { "id": "A0A8M9PK34", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PK34", "database": "AlphaFoldDB", "categories": [] }, { "id": "103908669", "url": "https://www.ncbi.nlm.nih.gov/gene/103908669", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:103908669", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103908669", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PK34", "url": "https://www.orthodb.org/?gene=A0A8M9PK34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325224", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325224", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PK34", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PK34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IGF7", "url": "https://www.uniprot.org/uniprotkb/A0AC58IGF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IGF7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IGF7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IGH5", "url": "https://www.uniprot.org/uniprotkb/A0AC58IGH5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IGH5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IGH5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKRISTFFQILLLTCSVFGADAEMKAVSVMEGDSVTLNPDQELQGIVLLLWKFGDNGSTIAHISGNKTSYPTKQKIFTDRLMLKETGSLTINNMRHNHSGRYKLEVDHSGGRLESSFFVTVDEPPLVFEAYQAERKSLTVTEGYPVILHTGITKLHGDELIVWRFGVEGKLLAKEDKEIKSPPYYDTDERFKGRLKLNDQTGSLTINNMKDTDAGLYTVKINNNKLTTYRDFTVTVSGSGLTSAAVAGIIIGLLMLFAVVAGSGFLYHRRMIAEQQKHMVKKIHTAERENVTLKTKTKLLEGDEIQWWFSNENFLIAEIIEGIGETYDGLDGRFSDILELDKKTGSLNIKNIRRKHTGDYRLKIIKRSRETSNFNFSVYIKEEKMIVSCGESVTLKADAEIQREDEVQWLFHIENDLIAKMTGNTREITYPDERFRDTLKMDEKTGSLTINNIGDEHTGLYKVKVISRGEATYKTFTVYINALINEKFIFDGRIGESVTLKPYIKIQRNNEIQWMIGDQDCLIAKMTRGARKITYHERFRDRLMLNEKTGSLTINNITIEDNRDYKLKIISSSGTTVKKFSVFIKGEPSFFCVGHTAVLQCAAEIQTDEIEWRFKGEESPIAEVKGGQIVPYNGPNRRFRDRLEVDKSNGSLIIKNIRREHEGLYKLKRKSSGTGDRVNAFTVTLCDSIIVGWVGKSVTLKSDTEIQRNYEILWLIEDSLIAKLTREAREITYYRFRDRLVLDEETGSLTINNITVEDNRDYKLRIISSSGTTVKKFGVLTKGEPMSFNEGDTAVLQCAAEIQTDEIEWRFKSEESPIAEVKGGKIILYNGPDRRFRDGLEVDKKTGSLIISNIRCEHKGLYQLMKKSSSTGDHISAFDVMVYGSTGNQVKDSVTEKSPLLYEDDQNVVYENERMSSL", "length": 918, "header": "tr|A0A8M9PK34-1|A0A8M9PK34_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC103908669 PE=4 SV=1 CANONICAL=A0A8M9PK34-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PK34-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK34/entry#A0A8M9PK34-1", "sequence": { "sequence": "MKRISTFFQILLLTCSVFGADAEMKAVSVMEGDSVTLNPDQELQGIVLLLWKFGDNGSTIAHISGNKTSYPTKQKIFTDRLMLKETGSLTINNMRHNHSGRYKLEVDHSGGRLESSFFVTVDEPPLVFEAYQAERKSLTVTEGYPVILHTGITKLHGDELIVWRFGVEGKLLAKEDKEIKSPPYYDTDERFKGRLKLNDQTGSLTINNMKDTDAGLYTVKINNNKLTTYRDFTVTVSGSGLTSAAVAGIIIGLLMLFAVVAGSGFLYHRRMIAEQQKHMVKKIHTAERENVTLKTKTKLLEGDEIQWWFSNENFLIAEIIEGIGETYDGLDGRFSDILELDKKTGSLNIKNIRRKHTGDYRLKIIKRSRETSNFNFSVYIKEEKMIVSCGESVTLKADAEIQREDEVQWLFHIENDLIAKMTGNTREITYPDERFRDTLKMDEKTGSLTINNIGDEHTGLYKVKVISRGEATYKTFTVYINALINEKFIFDGRIGESVTLKPYIKIQRNNEIQWMIGDQDCLIAKMTRGARKITYHERFRDRLMLNEKTGSLTINNITIEDNRDYKLKIISSSGTTVKKFSVFIKGEPSFFCVGHTAVLQCAAEIQTDEIEWRFKGEESPIAEVKGGQIVPYNGPNRRFRDRLEVDKSNGSLIIKNIRREHEGLYKLKRKSSGTGDRVNAFTVTLCDSIIVGWVGKSVTLKSDTEIQRNYEILWLIEDSLIAKLTREAREITYYRFRDRLVLDEETGSLTINNITVEDNRDYKLRIISSSGTTVKKFGVLTKGEPMSFNEGDTAVLQCAAEIQTDEIEWRFKSEESPIAEVKGGKIILYNGPDRRFRDGLEVDKKTGSLIISNIRCEHKGLYQLMKKSSSTGDHISAFDVMVYGSTGNQVKDSVTEKSPLLYEDDQNVVYENERMSSL", "length": 918, "header": "tr|A0A8M9PK34-1|A0A8M9PK34_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC103908669 PE=4 SV=1 CANONICAL=A0A8M9PK34-1" }, "locus": {} }, { "isoform_ac": "A0AC58IGF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK34/entry#A0AC58IGF7-1", "sequence": { "sequence": "MKRISTFFQILLLTCSVFGADAEMKAVSVMEGDSVTLNPDQELQGIVLLLWKFGDNGSTIAHISGNKTSYPTKQKIFTDRLMLKETGSLTINNMRHNHSGRYKLEVDHSGGRLESSFFVTVDEPPLVFEAYQAERKSLTVTEGYPVILHTGITKLHGDELIVWRFGVEGKLLAKEDKEIKSPPYYDTDERFKGRLKLNDQTGSLTINNMKDTDAGLYTVKINNNKLTTYRDFTVTVSGSGLTSAAVAGIIIGLLMLFAVVAGSGFLYHRRMIAEQQKHMVKKIHTAERENVTLKTKTKLLEGDEIQWWFSNENFLIAEIIEGIGETYDGLDGRFSDILELDKKTGSLNIKNIRRKHTGDYRLKIIKRSRETSNFNFSVYIKEEKMIVSCGESVTLKADAEIQREDEVQWLFHIENDLIAKMTGNTREITYPDERFRDTLKMDEKTGSLTINNIGDEHTGLYKVKVISRGEATYKTFTVYINALINEKFIFDGRIGESVTLKPYIKIQRNNEIQWMIGDQDCLIAKMTRGARKITYHERFRDRLMLNEKTGSLTINNITIEDNRDYKLKIISSSGTTVKKFSVFIKGEPSFFCVGHTAVLQCAAEIQTDEIEWRFKGEESPIAEVKGGQIVPYNGPNRRFRDRLEVDKSNGSLIIKNIRREHEGLYKLKRKSSGTGDRVNAFTVTLCGSTGNQVKDSVTEKSPLLYEDDQNVVYENERMSSL", "length": 721, "header": "tr|A0AC58IGF7-1|A0AC58IGF7_DANRE Computationally mapped isoform of Cell adhesion molecule CEACAM3 isoform X2 OS=Danio rerio OX=7955 GN=LOC103908669 PE=4 SV=1 CANONICAL=A0A8M9PK34-1" }, "locus": {} }, { "isoform_ac": "A0AC58IGH5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK34/entry#A0AC58IGH5-1", "sequence": { "sequence": "MSWSVNNSDDLIFCLFMSSEVLLTHYNLFSLFSCASVSREVKKIHTAERENVTLKTKTKLLEGDEIQWWFSNENFLIAEIIEGIGETYDGLDGRFSDILELDKKTGSLNIKNIRRKHTGDYRLKIIKRSRETSNFNFSVYIKEEKMIVSCGESVTLKADAEIQREDEVQWLFHIENDLIAKMTGNTREITYPDERFRDTLKMDEKTGSLTINNIGDEHTGLYKVKVISRGEATYKTFTVYINALINEKFIFDGRIGESVTLKPYIKIQRNNEIQWMIGDQDCLIAKMTRGARKITYHERFRDRLMLNEKTGSLTINNITIEDNRDYKLKIISSSGTTVKKFSVFIKGEPSFFCVGHTAVLQCAAEIQTDEIEWRFKGEESPIAEVKGGQIVPYNGPNRRFRDRLEVDKSNGSLIIKNIRREHEGLYKLKRKSSGTGDRVNAFTVTLCDSIIVGWVGKSVTLKSDTEIQRNYEILWLIEDSLIAKLTREAREITYYRFRDRLVLDEETGSLTINNITVEDNRDYKLRIISSSGTTVKKFGVLTKGEPMSFNEGDTAVLQCAAEIQTDEIEWRFKSEESPIAEVKGGKIILYNGPDRRFRDGLEVDKKTGSLIISNIRCEHKGLYQLMKKSSSTGDHISAFDVMVYGSTGNQVKDSVTEKSPLLYEDDQNVVYENERMSSL", "length": 679, "header": "tr|A0AC58IGH5-1|A0AC58IGH5_DANRE Computationally mapped isoform of Cell adhesion molecule CEACAM3 isoform X3 OS=Danio rerio OX=7955 GN=LOC103908669 PE=4 SV=1 CANONICAL=A0A8M9PK34-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103908669", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103908669", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 375, "end_pos": 377, "annotation": "n_glycosylation_sequon" }, { "start_pos": 556, "end_pos": 558, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 753, "end_pos": 755, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PK34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK34" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 125, "end_pos": 235, "start_aa": "Pro", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 290, "end_pos": 292 }, { "start_pos": 375, "end_pos": 377 }, { "start_pos": 556, "end_pos": 558 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 649, "end_pos": 651 }, { "start_pos": 66, "end_pos": 68 }, { "start_pos": 753, "end_pos": 755 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PK94-1", "uniprot_ac": "A0A8M9PK94", "uniprot_id": "A0A8M9PK94_DANRE", "mass": { "chemical_mass": 63355.0, "monoisotopic_mass": 63355.0 }, "refseq": { "ac": "NP_001119870", "name": "uncharacterized protein LOC561123", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119870" }, "gene_names": [ { "name": "fam222ba", "type": "recommended", "evidence": [ { "id": "A0A8M9PK94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94" } ] }, { "name": "fam222ba", "type": "synonym", "evidence": [ { "id": "NP_001119870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119870" } ] }, { "name": "si:dkey-9e15.1", "type": "synonym", "evidence": [ { "id": "NP_001119870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119870" }, { "id": "A0A8M9PK94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC561123", "type": "synonym", "evidence": [ { "id": "A0A8M9PK94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94/entry#names_and_taxonomy" } ] }, { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PK94", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC561123", "type": "synonym", "evidence": [ { "id": "NP_001119870", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119870" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01007665.1, SRR26395062.968953.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476740, SAMEA4476751 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000005.1. On Jul 31, 2008 this sequence version replaced XP_689620.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001119870", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119870" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK94", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam222ba", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-355", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-355", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "561123", "url": "https://www.ncbi.nlm.nih.gov/gene/561123", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561123", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561123", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MTHYTNG", "url": "https://omabrowser.org/oma/group/MTHYTNG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PK94", "url": "https://www.orthodb.org/?gene=A0A8M9PK94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16070", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16070", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16070:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16070:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15258", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15258", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001119870", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119870", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PK94", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PK94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-355", "url": "https://zfin.org/ZDB-GENE-060526-355", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLACLPGPGDLSLQLHPHSQMNTGLQKWDTPQRMRSAQYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRNHIRRTVNGLDTAGPRYSPYPSSQATAKTGLLAIVKVPLVKGVIKDFDGTRARLHPEVIMNATGGPYAATSASTLNLHHPSQAPSRASQNPQGLPPHPQNLQTLQQQQPGPPHQGLGHRPSSSIPPQHQGLPRPQTLCHAASLGHPSTHPPSAILLPQQHLQNPPASLQVGARKLPVADAPPNVTVSTSTIPLSMAGGLHQGRQADLNSIVHQISQFCQARAQGAGATSMCEGQIANPSPISRNLLINASSRVSVHAGNPNALAPGLMHPSFAIGPPDKMTASAPVSAAPPHNIGAMNHMYHSDLKQQHLQHQSHQLQRNPQHPHMRSWTQHQLPHLQHISEGGGHPCKPPGHDPGLSCKGITYPPEMSMGQPYAMKPSSPSPPLVNNNSSNAMPPGAVTHYTNGQYYHQPPVWGSILPTPNSDSSGSQDLPVSFHGTGTGNTNPTPGMDCGPTGGAAHYRLVGGALIGQTNLIQTADCMGGDFQTPCFRDQNLILMGKMHRPPPMGRVLVPPSETQGQHPGYR", "length": 595, "header": "tr|A0A8M9PK94-1|A0A8M9PK94_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=fam222ba PE=4 SV=1 CANONICAL=A0A8M9PK94-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PK94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94/entry#A0A8M9PK94-1", "sequence": { "sequence": "MLACLPGPGDLSLQLHPHSQMNTGLQKWDTPQRMRSAQYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRNHIRRTVNGLDTAGPRYSPYPSSQATAKTGLLAIVKVPLVKGVIKDFDGTRARLHPEVIMNATGGPYAATSASTLNLHHPSQAPSRASQNPQGLPPHPQNLQTLQQQQPGPPHQGLGHRPSSSIPPQHQGLPRPQTLCHAASLGHPSTHPPSAILLPQQHLQNPPASLQVGARKLPVADAPPNVTVSTSTIPLSMAGGLHQGRQADLNSIVHQISQFCQARAQGAGATSMCEGQIANPSPISRNLLINASSRVSVHAGNPNALAPGLMHPSFAIGPPDKMTASAPVSAAPPHNIGAMNHMYHSDLKQQHLQHQSHQLQRNPQHPHMRSWTQHQLPHLQHISEGGGHPCKPPGHDPGLSCKGITYPPEMSMGQPYAMKPSSPSPPLVNNNSSNAMPPGAVTHYTNGQYYHQPPVWGSILPTPNSDSSGSQDLPVSFHGTGTGNTNPTPGMDCGPTGGAAHYRLVGGALIGQTNLIQTADCMGGDFQTPCFRDQNLILMGKMHRPPPMGRVLVPPSETQGQHPGYR", "length": 595, "header": "tr|A0A8M9PK94-1|A0A8M9PK94_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=fam222ba PE=4 SV=1 CANONICAL=A0A8M9PK94-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 41, "start_aa": "Thr", "end_pos": 41, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr41", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 517, "start_aa": "Thr", "end_pos": 517, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr517", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 525, "start_aa": "Thr", "end_pos": 525, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr525", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Hematopoietic gene expression profile in zebrafish kidney marrow.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2004", "authors": "Song Huai-Dong, Sun Xiao-Jian, Deng Min, Zhang Guo-Wei, Zhou Yi, Wu Xin-Yan, Sheng Yan, Chen Yi, Ruan Zheng, Jiang Chun-Lei, Fan Hui-Yong, Zon Leonard I, Kanki John P, Liu Ting Xi, Look A Thomas, Chen Zhu", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK94", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94" } ], "reference": [ { "type": "PubMed", "id": "15520368", "url": "https://glygen.org/publication/PubMed/15520368" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK94", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Genomic conservation of erythropoietic microRNAs (erythromiRs) in white-blooded Antarctic icefish.", "journal": "Mar. Genomics", "date": "2016", "authors": "Desvignes Thomas, Detrich H William, Postlethwait John H", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK94", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94" } ], "reference": [ { "type": "PubMed", "id": "27189439", "url": "https://glygen.org/publication/PubMed/27189439" } ] }, { "title": "FAM222B Is Not a Likely Novel Candidate Gene for Cerebral Cavernous Malformations.", "journal": "Mol. Syndromol.", "date": "2016", "authors": "Spiegler Stefanie, Kirchmaier Bettina, Rath Matthias, Korenke G Christoph, Tetzlaff Fabian, van de Vorst Maartje, Neveling Kornelia, Acker-Palmer Amparo, Kuss Andreas W, Gilissen Christian, Fischer Andreas, Schulte-Merker Stefan, Felbor Ute", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PK94", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PK94" } ], "reference": [ { "type": "PubMed", "id": "27587990", "url": "https://glygen.org/publication/PubMed/27587990" } ] } ], "pathway": [ { "id": "dre:561123", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561123", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AT65-1", "protein_name": "Family with sequence similarity 222 member B", "gene_name": "FAM222B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAAAKAGLLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALSHQGLQHPPNPLLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRAPTGYPSDLKPVAWNQHQLAHLQQMCSEAGGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGLAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAVPFHGGQPAGAPLDCAAAAAAGAHYRAGTGGGPVASHNSLVQTVDYLSGDFQQACFREQSLALLSKAHRAPGSRAPDPTDSRSLHIQHPGYR", "length": 564 }, "evidence": [ { "id": "A0A8M9PK94", "url": "https://omabrowser.org/oma/group/A0A8M9PK94/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0ABK0L6G3-1", "protein_name": "Family with sequence similarity 222, member B", "gene_name": "Fam222b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLACLPGPGDLSFQLLSHTQMNAGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARVLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALTHQGLQHPPNPLLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRAPTGYPSDLKPVTWNQHQLAHLQQMCSEAGGTPAPGLTGKHTAGRELAGPGFVGKAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGLPAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQPTGAPLDCGAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRAPGARAPEPTDSRSLHIQHPGYR", "length": 562 }, "evidence": [ { "id": "MGI:2384939", "url": "https://alliancegenome.org/gene/MGI:2384939#orthology", "database": "AGR" }, { "id": "HGNC:25563", "url": "https://alliancegenome.org/gene/HGNC:25563#orthology", "database": "AGR" }, { "id": "RGD:1566149", "url": "https://alliancegenome.org/gene/RGD:1566149#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-355", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-355#orthology", "database": "AGR" }, { "id": "A0A8M9PK94", "url": "https://omabrowser.org/oma/group/A0A8M9PK94/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BFC5-1", "protein_name": "Family with sequence similarity 222 member B", "gene_name": "FAM222B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATRAGLLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALSHQGLQHPPTPLLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGVSTTSVCEGQIANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAASAALPPAGPVNLPAGLSRAPTGYPSDLKPVAWNQHQLAHLQQMCGEAGGTPAPGLTGKHAAGRELAGPGLVGKTPAYPQELCLAQSFHLKPPLEKPTPSPPVNGLAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAVPFHGGQPTGAPLDCAAVAAGAHFRAGTGGGPVASQNSLIQTVDYLSGDFQQACFREQSLAMLSKAHRAPGNRAPDPTDSRSLHVQHPGYR", "length": 563 }, "evidence": [ { "id": "A0A8M9PK94", "url": "https://omabrowser.org/oma/group/A0A8M9PK94/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "E7F6C1-1", "protein_name": "Protein FAM222B", "gene_name": "fam222bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLACLPVSNPSLQLLSHTQMNTGLQKWDTTQRMRSAHYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHIRRTVNGLDTSSQRYSPYPPQVNTRTGLLAIVKVPVKGILKDIEGGRARFLPKLIMNPHSGLYANPSTLNVPHTVPHLQTPLGQKSLGHSQALQAHPQSLQQKSSLQPQQSLAHQEALHQSQAHQPPVPHHTLNHQQTLMQQQLSAPQGLRHLPDMAQSVNLQHSQGFSQSQPIPQASCAGPPASGVLQPPLAGLQMPRKLPDADAPPNVTVSTSTIPLSMAASLHQNRPSDLNSIVNQINQFCQARAGMGSTSVCEGQIANPSPISRNQLINASSRVCPHPTVGPPSSCILGNSDKGGPASALPLPDIAAMNRIPLYHNEMKQQQSQPQLPQQQRQQGPWGQHQLGHLQHLPEGAAHQGKNLPREGLMGPGFLTKNMGYPQEVCMAQPFNLKPPTDKPTPSPPVNGMPVSYSNGHYMQPPWSNILPTPNSDSSGSQDLVGSFHGGLSGASLDCTPGAQYRTGAALSSQTNLMQNMEYMGGDFQTPCFRAQNPGTMAKMHRTPVNRATDSGDSRNVHIHHPGYR", "length": 596 }, "evidence": [ { "id": "MGI:2384939", "url": "https://alliancegenome.org/gene/MGI:2384939#orthology", "database": "AGR" }, { "id": "HGNC:25563", "url": "https://alliancegenome.org/gene/HGNC:25563#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6P539-1", "protein_name": "Protein FAM222B", "gene_name": "Fam222b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLACLPGPGDLSLQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARFLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQQMAQTQGLVHPQALTHQGLQHPPNPLLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRAPTGYPSDLKPVTWNQHQLAHLQQMCSEAGGTPAPGLTGKHTAGRELAGPGFVGKAAAYPQELCLAQSFHLKPPLEKPTPSPPVNGLPAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLTMPFHGGQPTGAPLDCGAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRAPGTRAPDPTDSRSLHIQHPGYR", "length": 562 }, "evidence": [ { "id": "MGI:2384939", "url": "https://alliancegenome.org/gene/MGI:2384939#orthology", "database": "AGR" }, { "id": "HGNC:25563", "url": "https://alliancegenome.org/gene/HGNC:25563#orthology", "database": "AGR" }, { "id": "RGD:1566149", "url": "https://alliancegenome.org/gene/RGD:1566149#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-355", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-355#orthology", "database": "AGR" }, { "id": "A0A8M9PK94", "url": "https://omabrowser.org/oma/group/A0A8M9PK94/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WU58-1", "protein_name": "Protein FAM222B", "gene_name": "FAM222B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLACLPGPGDLSFQLLSHTQMNTGLQKWDTTQKMRTAHYPTPAELDAYAKKVANNPLTIKIFPNSVKVPQRKHVRRTVNGLDTSAQRYSPYPTQAATKAGLLAIVKVPAKSILKDFDGTRARLLPEAIMNPPVAPYATVAPSTLAHPQAQALARQQALQHAQTLAHAPPQTLQHPQGIPPPQALSHPQSLQQPQGLGHPQPMAQTQGLVHPQALAHQGLQHPHNPLLHGGRKMPDSDAPPNVTVSTSTIPLSMAATLQHSQPPDLSSIVHQINQFCQTRAGISTTSVCEGQIANPSPISRSLLINASTRVSTHSVPTPMPSCVVNPMEHTHAATAALPAAGPVNLPTGISRVPTGYPSDLKPVTWNQHQLAHLQQMCSEASGTPAPGLTGKHAAGRELAGPGFVGKAPAYPQELCLAQSFHLKPPLEKPTPSPPVNGMAAPLAYPNGHYFQPLWNNILPTPNSDSSGSQDLAMPFHGGQPTGAPLDCAAAPGAHYRAGTGGGPVASQNSLMQTVDYLSGDFQQACFREQSLAMLSKAHRAPGNRAPDPTESRSLHIQHPGYR", "length": 562 }, "evidence": [ { "id": "MGI:2384939", "url": "https://alliancegenome.org/gene/MGI:2384939#orthology", "database": "AGR" }, { "id": "HGNC:25563", "url": "https://alliancegenome.org/gene/HGNC:25563#orthology", "database": "AGR" }, { "id": "RGD:1566149", "url": "https://alliancegenome.org/gene/RGD:1566149#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-355", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-355#orthology", "database": "AGR" }, { "id": "A0A8M9PK94", "url": "https://omabrowser.org/oma/group/A0A8M9PK94/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 132, "end_pos": 134, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 460, "end_pos": 462, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 41, 517, 525 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 132, "end_pos": 134 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 460, "end_pos": 462 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322721", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322721" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKD7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKD7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100535423", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKD7", "locus": {} } ], "crossref": [ { "id": "A0A8M9PKD7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PKD7", "database": "AlphaFoldDB", "categories": [] }, { "id": "100535423", "url": "https://www.ncbi.nlm.nih.gov/gene/100535423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016054", "url": 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This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021322746.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322746" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKF9#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKF9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKF9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101884350", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKF9", "locus": {} } ], "crossref": [ { "id": "A0A8M9PKF9", "url": 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SRR32588722.45045074.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Sep 16, 2025 this sequence version replaced XP_021322751.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001430399", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430399" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKG4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKG4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438015", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKG4", "locus": {} } ], "crossref": [ { "id": "A0A8M9PKG4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PKG4", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438015", "url": "https://www.ncbi.nlm.nih.gov/gene/110438015", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016054", "url": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PKG9-1", "uniprot_ac": "A0A8M9PKG9", "uniprot_id": "A0A8M9PKG9_DANRE", "mass": { "chemical_mass": 159758.0, "monoisotopic_mass": 159758.0 }, "refseq": { "ac": "XP_021327488", "name": "tensin-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327488" }, "gene_names": [ { "name": "tns2b", "type": "recommended", "evidence": [ { "id": "A0A8M9PKG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKG9" } ] }, { "name": "tns2b", "type": "synonym", "evidence": [ { "id": "XP_021327488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327488" } ] } ], "protein_names": [ { "name": "Tensin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PKG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKG9/entry#names_and_taxonomy" } ] }, { "name": "tensin-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021327488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327488" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021327488.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021327488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327488" } ] } ], "disease": [ { "disease_id": "DOID:0060852", "recommended_name": { "id": "DOID:0060852", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060852", "name": "Pierson syndrome", "description": "A syndrome characterized by nephrotic syndrome with diffuse mesangial sclerosis, proteinuria, microcoria, absence of the pupillary dilator muscle in the iris, ciliary muscle atrophy, and abnormal eye development with lens-shape, retinal and corneal anomalies that has_material_basis_in homozygous or compound heterozygous mutation in the LAMB2 gene on chromosome 3p21." }, "synonyms": [ { "id": "DOID:0060852", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060852", "name": "microcoria-congenital nephrosis syndrome", "description": "" }, { "id": "MONDO:0012184", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012184", "name": "Pierson syndrome", "description": "Pierson syndrome is characterized by the association of congenital nephrotic syndrome and ocular anomalies with microcoria." }, { "id": "MONDO:0012184", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012184", "name": "Pierson syndrome", "description": "" }, { "id": "MONDO:0012184", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012184", "name": "microcoria-congenital nephrosis syndrome", "description": "" }, { "id": "MONDO:0012184", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012184", "name": "microcoria - congenital nephrosis", "description": "" }, { "id": "MONDO:0012184", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012184", "name": "microcoria - congenital nephrotic syndrome", "description": "" }, { "id": "MIM:609049", "resource": "MIM", "url": "https://www.omim.org/entry/609049", "name": "Pierson syndrome", "description": "Pierson syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060852", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060852" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKG9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKG9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tns2b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKG9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-101001-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-101001-5", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PKG9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PKG9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01213", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01213", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09927", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09927", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20826", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20826", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "565809", "url": "https://www.ncbi.nlm.nih.gov/gene/565809", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029023", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029023", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035012", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035012", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051484", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051484", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565809", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565809", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR45734", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45734", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45734:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45734:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00130", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00130", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08416", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08416", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10409", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10409", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021327488", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327488", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PKG9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PKG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PRI6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PRI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-101001-5", "url": "https://zfin.org/ZDB-GENE-101001-5", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGCIFSKQQWEKETSSQPSDPPKTRDHAEDAEILSLTELEKMGSHCFKERNFKKKLHCAVCRQTLDSLGMYCRECKTAVHKKCEEKVSVPCEAVSDPPPLQNQMNVPQSKASMETVMENLMGSHYDFDLTYITERIISVLYQSDLDEQSYSANLKVVAPMLKSKHQDKFLLINLSEKRHDICRLNPKVEEFGWPDLHAPPLDKICAVCKTMENWLNSDPNNVVVLHCKGNKGKTGVIVAAYMHYSKISAGADQALSTVAMRKFCEDKISSFILPSQNRYIYYFAGLLSGSIKMNSSPLFLHQIHVPVSPNYQSGGGYAPFLKIYQSLQLVYSSGKYDIQGPNSKTLCVNIEPALLLKGDILVKCYHRLSDVCKRECVFRVQFHTCSVHGSQLAFGKGELDHACTDDRFPSDATVELLFSTGPQRRGGDVPGNEPGVSADYGSTDPVVRWDSYENFNLHHEDSVEDISHTRGPLDGSLYAQVKKRRAQGSSPSRCPTSIKPSTYSPTHSSSTSPIHLSVQPLSLSKDTSRSSAAPESLTPLPREKREKDENRERHRETAILDDGECSPLRPDRPVQSCYGHPFSHTHSYCGPDLTSPHAIAVQPKHRTLPCNRTTPLSVRDLCVSQPDLLWERGRCLHHPCPESVRHLYSYPPQETHTHSPIPQTSHSHTLPPQTRAYFSGEACPLFHCSALPQGHNHIPPSLSPNQSLLTSPYRELRYSTTSPTSCSCRDCLRLREDVALHSLRGRELETLPWSREAEFGIRREAPVHWRDGRAESHWEGVQEAEYWRRKIAMSPVMLSYGHCQAVPKQEQAVYVTDPQPEHGLSPFPSPQSSGYHSPHPPCPCSPQPFRDSPGYASISHSQNSSPIALTPSPKRANHNRASAEENQHGPNEEYTKILSDDKSPATFSPPTQNSGPVKAGEMVQIKSPEDVNLPVSLITNISSASGAEDKTTITDCTSNSLLISSQPSSKNMESVQVQTLNPRPLSVPESEQDKGERPGSCYTSTTTSTSPQPPLCSSERSSASEFSSFNLNGERQSVTPLTDCNEESNSDPDGFITPSFPIASHGYPLLTVPHVPYTGYTEITIPTNLAQPPLPEKQRSSPLHNTSDYTPTSLIKSAGKPSVSSAQVHVSFSTTTNEVPPKSTCRIPLSSGVDEPESRLSSKFVQDSSKYWYKPGISRDQAIAVLKDKEAGCFLIRDSNSFQGAYGLALKVSTAPAHTNSHTEPGSAQEQLVRHFLIESGAKGVKIKGCQNETYFGSLSALVYQHSITPVSLPCVLRIPDRDLVGELQDLQSGTNTSTAADLLKQGAACNVLYLNSVETESLTGPQAVSKTTKCTLTQEPRPSPTVVHFKVSTQGITLTDNQRRLFFRRHYPIHSVTFSSVDPLDQRWVDADNTSCKMFGFVARRSGALGNVCHLFAELDPEQPATAIVNFINKVMLGPQQLRK", "length": 1445, "header": "tr|A0A8M9PKG9-1|A0A8M9PKG9_DANRE Isoform 1 of Tensin-2 isoform X1 OS=Danio rerio OX=7955 GN=tns2b PE=3 SV=2 CANONICAL=A0A8M9PKG9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PKG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKG9/entry#A0A8M9PKG9-1", "sequence": { "sequence": "MGCIFSKQQWEKETSSQPSDPPKTRDHAEDAEILSLTELEKMGSHCFKERNFKKKLHCAVCRQTLDSLGMYCRECKTAVHKKCEEKVSVPCEAVSDPPPLQNQMNVPQSKASMETVMENLMGSHYDFDLTYITERIISVLYQSDLDEQSYSANLKVVAPMLKSKHQDKFLLINLSEKRHDICRLNPKVEEFGWPDLHAPPLDKICAVCKTMENWLNSDPNNVVVLHCKGNKGKTGVIVAAYMHYSKISAGADQALSTVAMRKFCEDKISSFILPSQNRYIYYFAGLLSGSIKMNSSPLFLHQIHVPVSPNYQSGGGYAPFLKIYQSLQLVYSSGKYDIQGPNSKTLCVNIEPALLLKGDILVKCYHRLSDVCKRECVFRVQFHTCSVHGSQLAFGKGELDHACTDDRFPSDATVELLFSTGPQRRGGDVPGNEPGVSADYGSTDPVVRWDSYENFNLHHEDSVEDISHTRGPLDGSLYAQVKKRRAQGSSPSRCPTSIKPSTYSPTHSSSTSPIHLSVQPLSLSKDTSRSSAAPESLTPLPREKREKDENRERHRETAILDDGECSPLRPDRPVQSCYGHPFSHTHSYCGPDLTSPHAIAVQPKHRTLPCNRTTPLSVRDLCVSQPDLLWERGRCLHHPCPESVRHLYSYPPQETHTHSPIPQTSHSHTLPPQTRAYFSGEACPLFHCSALPQGHNHIPPSLSPNQSLLTSPYRELRYSTTSPTSCSCRDCLRLREDVALHSLRGRELETLPWSREAEFGIRREAPVHWRDGRAESHWEGVQEAEYWRRKIAMSPVMLSYGHCQAVPKQEQAVYVTDPQPEHGLSPFPSPQSSGYHSPHPPCPCSPQPFRDSPGYASISHSQNSSPIALTPSPKRANHNRASAEENQHGPNEEYTKILSDDKSPATFSPPTQNSGPVKAGEMVQIKSPEDVNLPVSLITNISSASGAEDKTTITDCTSNSLLISSQPSSKNMESVQVQTLNPRPLSVPESEQDKGERPGSCYTSTTTSTSPQPPLCSSERSSASEFSSFNLNGERQSVTPLTDCNEESNSDPDGFITPSFPIASHGYPLLTVPHVPYTGYTEITIPTNLAQPPLPEKQRSSPLHNTSDYTPTSLIKSAGKPSVSSAQVHVSFSTTTNEVPPKSTCRIPLSSGVDEPESRLSSKFVQDSSKYWYKPGISRDQAIAVLKDKEAGCFLIRDSNSFQGAYGLALKVSTAPAHTNSHTEPGSAQEQLVRHFLIESGAKGVKIKGCQNETYFGSLSALVYQHSITPVSLPCVLRIPDRDLVGELQDLQSGTNTSTAADLLKQGAACNVLYLNSVETESLTGPQAVSKTTKCTLTQEPRPSPTVVHFKVSTQGITLTDNQRRLFFRRHYPIHSVTFSSVDPLDQRWVDADNTSCKMFGFVARRSGALGNVCHLFAELDPEQPATAIVNFINKVMLGPQQLRK", "length": 1445, "header": "tr|A0A8M9PKG9-1|A0A8M9PKG9_DANRE Isoform 1 of Tensin-2 isoform X1 OS=Danio rerio OX=7955 GN=tns2b PE=3 SV=2 CANONICAL=A0A8M9PKG9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PRI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKG9/entry#A0A8M9PRI6-1", "sequence": { "sequence": "MGCIFSKQQWEKETSSQPSDPPKTRDHAEDAEILSLTELEKMGSHCFKERNFKKKLHCAVCRQTLDSLGMYCRECKTAVHKKCEEKVSVPCEAVSDPPPLQNQMNVPQSKASMETVMENLMGSHYDFDLTYITERIISVLYQSDLDEQSYSANLKVVAPMLKSKHQDKFLLINLSEKRHDICRLNPKVEEFGWPDLHAPPLDKICAVCKTMENWLNSDPNNVVVLHCKGNKGKTGVIVAAYMHYSKISAGADQALSTVAMRKFCEDKISSFILPSQNRYIYYFAGLLSGSIKMNSSPLFLHQIHVPVSPNYQSGGGYAPFLKIYQSLQLVYSSGKYDIQGPNSKTLCVNIEPALLLKGDILVKCYHRLSDVCKRECVFRVQFHTCSVHGSQLAFGKGELDHACTDDRFPSDATVELLFSTGPQRRGGDVPGNEPGVSADYGSTDPVVRWDSYENFNLHHEDSVEDISHTRGPLDGSLYAQVKKRRAQGSSPSRCPTSIKPSTYSPTHSSSTSPIHLSVQPLSLSKDTSRSSAAPESLTPLPREKREKDENRERHRETAILDDGECSPLRPDRPVQSCYGHPFSHTHSYCGPDLTSPHAIAVQPKHRTLPCNRTTPLSVRDLCVSQPDLLWERGRCLHHPCPESVRHLYSYPPQETHTHSPIPQTSHSHTLPPQTRAYFSGEACPLFHCSALPQGHNHIPPSLSPNQSLLTSPYRELRYSTTSPTSCSCRDCLRLREDVALHSLRGRELETLPWSREAEFGIRREAPVHWRDGRAESHWEGVQEAEYWRRKIAMSPVMLSYGHCQAVPKQEQAVYVTDPQPEHGLSPFPSPQSSGYHSPHPPCPCSPQPFRDSPGYASISHSQNSSPIALTPSPKRANHNRASAEENQHGPNEEYTKILSDDKSPATFSPPTQNSGPVKAGEMVQIKSPEDVNLPVSLITNISSASGAEDKTTITDCTSNSLLISSQPSSKNMESVQVQTLNPRPLSVPESEQDKGERPGSCYTSTTTSTSPQPPLCSSERSSASEFSSFNLNGERQSVTPLTDCNEESNSDPDGFITPSFPIASHGYPLLTVPHVPYTGYTEITIPTNLAQPPLPEKQRSSPLHNTSDYTPTSLIKSAGKPSVSSAQVHVSFSTTTNEVPPKSTCRIPLSSGVDEPESRLSSKFVQDSSKYWYKPGISRDQAIAVLKDKEAGCFLIRDSNSFQGAYGLALKVSTAPAHTNSHTEPGSAQEQLVRHFLIESGAKGVKIKGCQNETYFGSLSALVYQHSITPVSLPCVLRIPDRDLVGELQDLQSGTNTSTAADLLKQGAACNVLYLNSVETESLTGPQAVSKTTKCTLTQEPRPSPTVVHFKVSTQGITLTDNQRRLFFRRHYPIHSVTFSSVDPLDQRMFGFVARRSGALGNVCHLFAELDPEQPATAIVNFINKVMLGPQQLRK", "length": 1435, "header": "tr|A0A8M9PRI6-1|A0A8M9PRI6_DANRE Computationally mapped isoform of Tensin-2 isoform X2 OS=Danio rerio OX=7955 GN=tns2b PE=3 SV=2 CANONICAL=A0A8M9PKG9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1346, "start_aa": "Thr", "end_pos": 1346, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1346", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:565809", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565809", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A502-1", "protein_name": "Tensin 3", "gene_name": "Tns3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRPGDPQGSGARAVRGDCPSRLEGALPRARAASQEDGPAREQLGAQLRFGHRPAGLRCGFAQPEEFTTCPHSFKKKDFKKHRVCGVCRQTIDGQGIACRTCKYSCHKKCEAQVVTTCSAQVHLDQAPEGSTPSAPLRCDKPSRPVVLSSAMEDSHELDLTYVTERIIAVSFPASCSEESYLHSLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMEPSQKRYVQFLSGLLSGAVKMNASPLFLHFVILHGAPSFDTGGACRPFLKLYQAMQPVYTSGIYNVGSENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGSEHLYSDQGVTVDYNTADPLIRWDSYENMSADGEVLHTQGPVDGSLYAKVRKKSASDSGIPSSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERQTPGARRGLSPQEKAELDQLLSGFGLEDSANSHKDMTDMRSKYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSTHLGPFACLKSSQNSLLSDGFGNGVAEDHNGVLSPDLGLGVDSVYERERMCGGREQKQLQPLSRKPSAPTPTQAYGQSNYSTQTWVRQQQMVTAHQYSFASDGEARHGSRSAVDSAGLAQPSPHIPVTPTHGTSSRVAVQRGISNGPNPPDAQQLCPSKALQPRFPDDRVMNGVVHQELNPGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHLSALGLSANGSMYPDGVGSGLRCGGRLDPVDGPGRSPGRQGDDPVGGRLRKLSIGQYDNDAGSQVTFSKCGWGKAGADSAPSLGSFSSPADIKETVITAYPPDLDVIDGRIPNSKESPICLTPAFPVSPETPYVKTSPRYPPFSPPEPQLSIPASLHKGREPRGCTEIISHTVGMSESPLGSKPTLLRADMPATPNFQQVFAASCTVSSNGPGQRRESPPSAERQWAESSPKSTLTLLGNNRPSESPLGTHEFCSSGKNSPGLPCFQSSELQASFHSHELSMSESQDAMPPAGSQTFLGFNTVTTVTSGLPPSEDAGTLLVNSHGPSPVPGTPLTTTGAADNGFLSHNFLTVSPGASSHHSPGLQNQGISLPGQPPLPEKKRTSEGDRSLGSVSPSSSGFSSPHSGSTMSIPFPNVLPDFCKPSEVATPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAVQKALNMTLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVSSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI", "length": 1595 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A656-1", "protein_name": "Tensin-1", "gene_name": "Tns1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCTVSLVCCEALEPLPSCGPQPPGTPPGPARPERSEPGGAASIQRRRLLLQPEDLEAPKTHHFKVKAFKKVKPCGVCRQAITREGCICKVCSFSCHRKCQAKVAAPCVPPSSHELVPIATESVPKNVVDVGEGDCRGGSTPKNLEEAGSMRVSPSIQPQPQPQPQPISLSRNLSVSRAMEDSCELDLVYITERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSEQRPDITKLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYMHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQASICITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDEAFKDDRFPDYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFNGHREDGMEEVVGHTQGPLDGSLYAKVKKKDSLNGSSGPITTARPALSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVSGAAIAPAALSPQEKKELDRLLSGFGVDREKQGAMYRAQQLRSHPGGGPTVSSPGRHIVPAQVHVNGGALASERETDILDDELPIQDGQSGGSMGTLSSLDGVTNTSEGGYPETLSPLTNGLDKPYPTEPILNGGGYPYESANRVVPVHSSHSAPIRPSYSAQEGLGGYQREGPHPAWSKQVTSAHRGYDPSGLFRSQSFPDVEPQLPQAPARGGSSREAVQRGLNSWQQQQQQQQQQQQQQQQQQQQQPHPPPRQQERSPLQSLACSKPSPHLSAETPIPALPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLLGSSCQSHPLTQSRSGYIPSGDTLGAPELLSSGRSYSPYDYQLHPAASNQSFRPKSPASSTFLPSPHSSAGPQEPPASLPGLIAEPQLPLKETTSDTSRTPEEEPLNLEGLVAHRVAVYNARLQSLRQSSSSRPSLHRLRSASLSRVQARERQPAEPPAPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPPSVARSPPGLAKTPLSALGLKPHNPADILLHPTGEPRSYVESVARTAVAGPRAQDVEPKSFSAPATHAYGHETPLRNGTPGGSFVSPSPLSTSSPILSADSTSVGSFPSAGSSDQGPRTPIQPMLDSSIRSGSLGQPSPAALSYQSSSPVPVGGSSYSSPDYSLQPFSSSPESQGQPHFSAASVHMVPGSPQARHRTVGTNTPPSPGFGRRAINPTMAAPGSPSLSHRQVMGPSGPGFHGNVVSGHPTSATVAPGSPSLGRHPVGSHQVPGLHSGVVTTPGSPSLGRHPGAHQGNLVSSLHGNAVISPGSPSLGRHLGGSGSVVPGSPSLDRHVAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSSPVANGMASPSGSSTVSFSHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTITQQGKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSVIPLALPCKLVIPSRDPTDESKDSSGPANSTTDLLKQGAACNVLFINSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLSAGQKR", "length": 1916 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AQ81-1", "protein_name": "Tensin 2", "gene_name": "Tns2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLALSSARRSASEVGATPYPILLLLVPRAQCSSSQESPTLSRSTSKNPVHPSVMGMRSQAVEEGVPPSVPRWTSFCIVKPRKAEPHSFREKVFRKKAPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSSCQALPPAELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVHDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGSKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKAAMELQPSQHRYVGYFSGLLSGSIRMNSSPLFLHYVFVPVLPAFEPNTGFQPFLKIYQSMQLVYTSGVYHITGPGPRQICISLEPALLLKGDVMVTCYHKGGQGTDRTLVFRVQFHTCTIHGPRLNFPKDQLDEAWADERFPFQASVEFVFSSSPEKVKGNTPRNDPSVSVDYNMTEPAVRWDSYENFNQHHEDSVDGSLAHTRGPLDGSPYAQVQRVPRQTPPAPSPELPPPPMLSVSSDSGHSSTLTTEHTAESPGRPPPTAAERQELDRLLGGCGVASAGRGAGRETAILDDEEQPSVGGGLHLGMYPGHRPGLSRRCSCRQGLREPCGVPNGGYYRPEGTLERRRPPYGGYEGHPQGYTEASVEKRRLCRSLSEGPYPYAPELGKPANGDFGYRPAGYREVVILEDPGVPALCSCPACEEKMALPTAALYGLRLEREAGEGWSSEVGKPLLHPVRPGHPLPLLVPACGHHHAPVPDYGCLKSPKVGEEGHEGCSYAVCPEGRYGHPGYPALVTYGYGGAVPSYCPAYGRAPHSCGSPSEGRGYPSPGAHSPQAGSVSPGSPPYLQSRKLGYEAPAEDGRDKYSLPGPLASAGPLASTESPEPSWRDGSSGHSTLPRSPRDAQCSASSELSGPSTPLHTSSPVQGKESTRRQDTTRSPSLAPTQRLSPGEALPSVVQGVTEKTPELLASSRPEPLDPSPFSQTSTPSSPNGWPQERSPGGHTNSASPRSPVPTTLPGLRHAPWQGPQGPSDSPDGSPLTPVPTQMPWLVGSPEPPQSSPTPAFPLATSYETNGPTQPPLPEKRHLPGSGQQSSPPARGTNQHVTFASPLPDVTQPPEHPLQENQSSVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPSEQLVRHFLIETGPKGVKIKGCPTEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETSEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPVPVPAIVHFKVSAQGITLTDNQRKVFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPASAIVTFITKVLLGQRK", "length": 1454 }, "evidence": [ { "id": "HGNC:19737", "url": "https://alliancegenome.org/gene/HGNC:19737#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-101001-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-101001-5#orthology", "database": "AGR" }, { "id": "MGI:2387586", "url": "https://alliancegenome.org/gene/MGI:2387586#orthology", "database": "AGR" }, { "id": "RGD:1310917", "url": "https://alliancegenome.org/gene/RGD:1310917#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9PL00-1", "protein_name": "Tensin-2 isoform X1", "gene_name": "tns2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCALSGDSCGDEPDPVPVRGSLRRERAKSRGNMRLTKAGKGEPHVFKEKAFKKKRQCGVCRQSVENLGSFCRVCKTATHKKCEAKINTACIPAQPSELRRGTSSSRHIQHLGSTKSLTYTKQRNTLPRSFSVDRVMDRVMERHYDFDLTYITERIISVFFPPLLEEQRYRLNLREVAAMLKSKHQDKFLLLNLSERRHDITRLNPKVHDFGWPDMHSPPLDKICAMCKAMENWLNSDPQHVVVLHCKGNKGKTGVIIAAYMHYSKISAGADQALSTLAMRKFCEDKVASSLQPSQNRYIQYFGGLLSGSIKMNSSPLFLHQVLIPTIPNFQEDDGFFPFLKIYQSMQLVYTSGIYDLQGSASRRLIITIEPALLLKGDIMVKCYHRRVESAERDSVFRLQFHTCTVHAAQLWFGKGELDEACSDDKFPPDAIVEFVFSSGPEKIKGRVSQRNDPAVSVDYNTNDPVVRWDSYENFNQRHQDSLEDIAHTRGPVDGSLYAQVKKRRAAAGCSSLPSTNGSPARSSEERPSQLLSVSTDSGHSSVPPDRLDEPTRPAPPTQQEREELERLLGGIEGDGLRDRDRETAILDDGDSLPPERTGSLRLGRSCSCRVGYRSQGCAEPGCNGFHHLPNGHCLDRPTTTNGHTGALSPGMSSVIGLCQHHSTHPHQSLPPPDLLWDRQQGPQHYLHRTCSEGPSRHLYPYPSQEINSHPHSLSPRLLCRPDEYISYPHHHHNHSHHPKPSGPYHDVMMIDGLVTPGCPCRDCALRREEFHTLRLDREDGIHWEREAELHRDNGLRRTREADMQRGAEIWEREPGLRRGREMSLHWDRDRDAELQWEREREAEYWHRRATVSPYGPHGHELPAFNFDPLPAGHPAYPEPSRSHSHAHLDLKYSSSSSGYQTPHQTCPCSPYQPSPSESRGYASGYQSESTSPLPPPSASCPGPVHHASGPTENQTDPHSQHFTSDSNTDCPGADSIGWRNHITHGSLRRMHPHAPYSTPSDISGPPTPVHTSSPLRTQESPSLSVRDYDSREGNSESSSAHSLNRPHPATIQPNMTNAGSRQTLLSSSPETPEINPLPTTPTTAQHLAAHSLPTTPPTPQIATEHSPPLTPESESTQPQANCSPTAATVLPTVEMVPQSTETIKPAHSPHPSSPVLAESIPAHMQSNGVPPSPESDAPKPASSAPASPQPPAGDHESSSSPEPSVPGFATLGRKLMLGSETSLSAGHSMDASSNSTPTFPVSPACCTPSPPPGSYPGCPSSSVPQPPLPEKRRPSGLPGSPNGRSGTLRASMSHQPSGQHHVTFSPSVGELAVPIGQVEVGVEGEIGNRVSVKFVQDSSRFWYKPGISREQAIAALKEREPGAFLIRDSNSFQGAYGLALKVASPPPNVNNHSSKGDPLEQLVRHFLIETGPRGVKIKGCQNEPYFGSLSALVYQHSITPISLPCALRIPEKDPIGDVVEVQPVSNMSTAADLLKQGAACNVLYLNSVETESLTGPQAIAKATGATLSRSPRPSATVVHFKVSAQGITLTDSQRRVFFRRHYPINSVTYSSIDPQDRRWTNSDSTTSKVFGFVAKKPGSVAENVCHLFAELDPEQPATAIVNFINKVMLAPQRR", "length": 1616 }, "evidence": [ { "id": "HGNC:19737", "url": "https://alliancegenome.org/gene/HGNC:19737#orthology", "database": "AGR" }, { "id": "MGI:2387586", "url": "https://alliancegenome.org/gene/MGI:2387586#orthology", "database": "AGR" }, { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" }, { "id": "RGD:1310917", "url": "https://alliancegenome.org/gene/RGD:1310917#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PT37-1", "protein_name": "Tensin-1 isoform X1", "gene_name": "tns1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCTVSFICCEDDFLQMPLDQHVEKKKEEKRLLFKPEEFEAVHSHTFRLKTFKKGKHCGVCKQTVNNEGLICRVCRLACHRKCEVKVSSSCVPVANYELAPSNELPLKHIETTGSTKSSKSMESRRRPSRSLSLIQAMEENYEVDLVYITERIISVTFPSNAEEPSYSANIKEVANMLRSKHGDNYLLFNLSEKRLDISKLNPKVLDFGWPDHHAPALDKICSICKAMDTWMNAGSHNVVVIHNKGNRGRTGVVVAAYMHYSNISASADQALDRFAMKRFYEDKVLPVGQPSQRRYVQYFSGLLSGHIKINNKPLFLHHVIMHGIPNFESKGGCRPFLKIYQAMQPVYTSGIYNVQGDSQTSICITIEPGLLLKGDILLKCYHKRFRSPCRDVIFRVQFHTCAVHDLGIVFGKDELDETFKDDRFPEYGKVEFVFSFGPEKIQGMDHLENGPSVSVDYNTQDALIRWDSYENFNQRCEDSMEDVIHTEGPLDGSLYAKVRKKESLEGGVTANGLPAAADHTLPAVDHTLPPVDHALSVSSDSGNSTASIKTDRTDEASHQPALVSQPSSQPLSPEEKQELDQLLSGLEAPMHRTGYQSSPGGGGGGGGGGVLHLVPAQVHVNGHSNIDRETDILDDDLPISQEGNSVDSLGTLSSFEGRATPADLYYQSETVINGQDMPYLEKIVHEKMLEPRVHSSSSVQEHLGGPSGYANQNGNIYRSQSLGATPNTDQKYMPKAPARTTSSRDAVQRLNVWQQYGVPEVPVTDGVTFNPVLQSHSLPEFPQMASQQEIEQSIEALNMLMLDLDPALTQVPKSHSAPSGESGVVTTQPSFSQTQARPSYQADTAIHDRGAASSMGFPLTFQQVTGEPSQPTMKQQKPTTTSQHVEFASEAGGQAPMSQSTVPSSTFGVLQLKPLNIYPSSTTSQSPEPQETQRSYSSSSSPLPKESEPEDSSYKLEGLVAHRVAEYTARIRCINDSQSAPEFGHRRRSLSFSGLPSGEMSPDEAAVPGRCRTRSEGLSQDESPTRGSSVRSPIRCISPELANTIALNPGGRPKERHMHSYREAFEEMDGGPVSPPPIVGGEVLPQTPAFPVSPQTPYFNMCRSPPGLAKTPLSFLGLKPHNPAEILLNQTGSESEDEEEPRSYVESVAKAAAVPASPTYDSDSLARPAGPSHAYNAPLSSSSPIQNPDPVESTLADSGVGMNSLSQAAVDIFHFQPSEIPYQPPPPPYPTSMLGSYISPSPAEAMQNNTTTIQPLSGSPGTRHHTILSDMASVPNFQHRLANQDGPILGRQQAPANGHVPGIAGSPVQGRHTMVSQGTQSSPILSRQYPVTQGIQSSPILSRQPMGQAVQSSPVLNRQASLNQANQSSPVLSRQQSITLPNQGSPVLSRQSSLSHPSQGSPVLGRHPSLTQGSPSLDRHPMYSGYTTPEERHGALSRQSSSSGYQPPSTPSFPVSPAGYIEGAGFRQGSPAFQPQLPEKRRMSSSDRTNGGLSYGTLNGKMSSPVSSGGSTPSVHFFHTLPDFSKLNMCDGSPETRMNVKFVQDTSKFWYKPDISRDQAINMLKDQDPGAFVIRDSHSFRGAYGLAMKVASPPPTTQPTKKAGDVTNELVRHFLIETSPKGVRLKGCPNEPYFGCLSALVYQHSITPLALPCKLVIPTRDPLEESPEIATPTNPAADMLKQGAGQKSSADGHACNVLYINSVDMESLTGPQAIAKAISETMNASPAPSATIVHFKVSAQGITLTDNQRKLFFRRHYPIGTVTFCDIDPQERKWNKPEGGTAKFFGFVARKQGSTTDNVSHLFAEMDPDQPATAIVNFVSKVMISSQKR", "length": 1830 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A8N8-1", "protein_name": "Si:ch211-191a24.3", "gene_name": "tns3.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEGSEFDLNYITERVIGITFHQTCTEQTYQHNLSRITQLLQSKHADRYMVINLSEHSDDLCRMNHRVVDLGWPESHAPSLHLLCSVCKNMDSWLSAHPDNVLLLHCKGSKDRVGVVISSYIQLSSVSTSEEHALDLYSMKRFCSDQMVNLLTPSQKRYVQVFGRLLKHQIPLNHSPLFIHHVTIHPIPDFHPTVCQLFIRVNQGTQTAYTSGLHQVDVGLMDRVCFVLDPPQMIKGDIMIVCYHKNVSTRTQETLFRAQFHTAALSAKQFALQKEDLDLANKDPRFPENCVVEVLFSEVADKDPTLASDCDQWRSSLAVVIENDLPDSLQTQWDLSENLPATAKPHEGTRSLSSDSGLSSSSQWTGGQASGLLISYSPEENNQLNTVTPGLRMEEEQSSPGTLRRDPTTSQSVLDYSGHLNGDSMFTERETDIIDDDEDDITSPNDAIAAVSDSLSFKETSGLSSGQSSDYQNEASPAKFRGDVNTSNSVIDTSVPAGYQTRIWVKQQQSTSYAHTPTDRLEVKQELRSDASKPSTPDNCLPEAPSETDKDDVMALDQSIEQLNQLILDLDPEFKPIPTQPQSHMTRSASLYTNGKTQSMGKAKSHLSGWRQKQLSDVSEYSVLQNTSGDQTQNTQRFDFSTPSLRGLYHTDAVDFGDLPPEVDRPLWVGLNQAPPTPAFPVTPPTPYVKSGNDFTNSRPGSQTSRHYMSSPVWQESRGFTDSMTHTSMSSDGEIFHSDVTGSPASCQRMFGSLHSISTPSPLVNADSPTPAHSWLEGGSSTPLSHYTPQPSPPLTLSAPNSHSSPRRAPRSLSSALDMGSLESSLLEAVEGLEALGLDVAQPPLLPLKRRGTDGSENMLSFPLSRSTVSTSYASHNTSPSRSTPSPDFMASKPENVKFVQDTSKFWYKPDISREQAISVLKDKEPGSFIIRDSHSFRGAYGLAMKVATPPPTVLQTSRKVGDLSNELVRHFLIECTPKGVRLKGCPNEPYFGSLTALVCQHSITPLALPCRLIIPSRDPLEEFNESPTQTSTNSAAELLKQGAACNVWFLGSVDLESLTGVQGVQKATTVTFNKDPPPTSTVVHFKVSAQGITLTDNQRKLFFRRHYAVSTVIFCALDPQDRKWKRDGCTAAKIFGFIARKSGSSTENVCHLFAEHDPEQPASAIVNFVSKVMIGSQKNK", "length": 1182 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q0S6-1", "protein_name": "Tensin-1", "gene_name": "Tns1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCTVSLVCCEALEPLPSCGPQPPGTPPGPARPERCEPGGAAPDPRRRLLLQPEDLEAPKTHHFKVKAFKKVKPCGICRQAITREGCVCKVCSFSCHRKCQAKVAAPCVPPSSHELVPITTETVPKNVVDVGEGDCRVGSSPKNLEEGGSMRVSPSIQPQPQSQPTSLSRNTSVSRAMEDSCELDLVYVTERIIAVSFPSTANEENFRSNLREVAQMLKSKHGGNYLLFNLSEQRPDITKLHAKVLEFGWPDLHTPALEKICSVCKAMDTWLNADPHNVVVLHNKGNRGRIGVVIAAYLHYSNISASADQALDRFAMKRFYEDKIVPIGQPSQRRYVHYFSGLLSGSIKMNNKPLFLHHVIMHGIPNFESKGGCRPFLRIYQAMQPVYTSGIYNIPGDSQASICITIEPGLLLKGDILLKCYHKKFRSPARDVIFRVQFHTCAIHDLGVVFGKEDLDEAFKDDRFPDYGKVEFVFSYGPEKIQGMEHLENGPSVSVDYNTSDPLIRWDSYDNFSGHREDGMEEVVGHTQGPLDGSLYAKVKKKDSLNGSSGPVTTARPALSATPNHVEHTLSVSSDSGNSTASTKTDKTDEPVSGATTAPAALSPQEKKELDRLLSGFGVDREKQGAMYRAQQLRSHPGGGPTVPSPGRHIVPAQVHVNGGALASERETDILDDELPIQDGQSGGSMGTLSSLDGVTNTSESGYPETLSPLTNGLDKPYSTEPVLNGGGYPYEAANRVIPVHSSHSAPIRPSYSAQEGLAGYQREGPHPAWSQQVTSAHCGCDPSGLFRSQSFPDVEPQLPQAPTRGGSSREAVQRGLNSWQQQQPHPPPRQQERSPLQSLARSKPSPQLSAETPVAALPEFPRAASQQEIEQSIETLNMLMLDLEPASAAAPLHKSQSVPGAWPGASPLSSQPLLGSSRQSHPLTQSRSGYIPSGHSLGTPELVSSGRPYSPYDYQLHPAGSNQSFHPKSPASSTFLPSPHSSAGPQEPPASLPGLIAQPQLPPKETTSDPSRTPEEEPLNLEGLVAHRVAGVQARERQPAEPPGPLRRRAASDGQYENQSPEATSPRSPGVRSPVQCVSPELALTIALNPGGRPKEPHLHSYKEAFEEMEGTSPSSPPHSVARSPPGLAKTPLSALGLKPHNPADILLHPTGVARRLIQPEEDEGEEVTKPPEEPRSYVESVARTAVAGPRAQDVEPKSFSAPAAHAYGHETPLRNGTPGGSFVSPSPLSTSSPILSADSTSVGSFPSVVSSDQGPRTPFQPMLDSSIRSGSLGQPSPAALSYQSSSPVPVGGSSYNSPDYSLQPFSSSPESQGQPQYSAASVHMVPGSPQARHRTVGTNTPPSPGFGRRAVNPTMAAPGSPSLSHRQVMGPSGPGFHGNVVSGHPASAATTPGSPSLGRHPVGSHQVPGLHSSVVTTPGSPSLGRHPGAHQGNLASSLHSNAVISPGSPSLGRHLGGSGSVVPGSPSLDRHAAYGGYSTPEDRRPTLSRQSSASGYQAPSTPSFPVSPAYYPGLSSPATSPSPDSAAFRQGSPTPALPEKRRMSVGDRAGSLPNYATINGKVSSSPVANGMASGSSTVSFSHTLPDFSKYSMPDNSPETRAKVKFVQDTSKYWYKPEISREQAIALLKDQEPGAFIIRDSHSFRGAYGLAMKVSSPPPTITQQGKKGDMTHELVRHFLIETGPRGVKLKGCPNEPNFGSLSALVYQHSVIPLALPCKLVIPSRDPTDESKDSSGPANSTTDLLKQGAACNVLFVNSVDMESLTGPQAISKATSETLAADPTPAATIVHFKVSAQGITLTDNQRKLFFRRHYPLNTVTFCDLDPQERKWMKTEGGAPAKLFGFVARKQGSTTDNACHLFAELDPNQPASAIVNFVSKVMLSAGQKR", "length": 1888 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4V8I3-1", "protein_name": "Tensin-4", "gene_name": "Tns4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSSLLTGGHVVSLTPHEESRMALHPTPSHDLPALCPYYTTESWGTQPLMDPTLCKGSSNRLQQAQQAEARAQCLLQCPGEQASGASQDLDSCIDFSLEALNKMILELDPTFQLLPSGIAGPQAEPTNSVASRTKKEEPDALDIKYIEVTSTRSRCLDSPQRCSSPCVTPPFGSPRSGGLFLSRDIPRETRSSSNESLIFSGNQGRGSSPHTPSSLSNSIPCRESRASGSPLATPPGWEKGLRAPQWGSRVSTLSASPVSDISYVFGSNQSLPHSSLSSYPPSSRSLGSPASSSSSLHSLDRGSQCVRSSDAQVPSNPIVGMGQPQAVPSTPVAKEQASSCPPSVTNSMADIPIVLINGNPEPQSPPAQQTPRYQDSVQSRATSPSHLCQATKSHSKTLPDVPLTSPSHLCQATKSHSKTLPDVPLTASPESPAKDMQPTMKFVMDTSKYWFKPSITREQAINLLRTEKPGTFVIRDSSSYRGSFGLALKVQETPASAPNRPGEDSTDFIRHFLVESSAKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQKELGGAEPASDSPTHGQTSCLKISAGCHTLYLTSVSVETLSGALAVQKAISVMLERDVLPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLIALRFCGMDPEQRKWQKYCKPSRIFGFVAKSQTEPQENACHLFAEYDAAQPASQVISLVTALLKDTERV", "length": 718 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5SSZ5-1", "protein_name": "Tensin-3", "gene_name": "Tns3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDSHELDLTYVTERIIAVSFPASCSEESYLHSLQEVTRMLKCKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNNDPQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKISALMEPSQKRYVQFLSGLLSGAMKMNTSPLFLHFVIMHGVPSFDTGGACRPFLKLYQAMQPVYTSGIYNVGSENPSRIRIAIEPAQLLKGDIMVKCYHKKFRSATRDVIFRLQFHTGAVQGYGLLFGKEELDSACKDDRFPDYGKIELVFSATPEKIQGSEHLYSDQGVTVDYNTADPLIRWDSYENMSADGEVLHTQGPVDGSLYAKVRKKSASDTGIPSSPQGMPATSSPDHGDHTLSVSSDSGHSTASARTDKTEERLTPGARRGLSPQEKAELDQLLSGFGLEDSASSHKDMTDMRSKYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSTHLGPFTCLKSSQNSLLSDGFGNGVAEDHNGVLSPDLGLGVDTLYDRERMCGGREQKPLQPLLRKPSAPTPVQAYGQSNYSTQTWVRQQQMVAAHQYSFASDGEARLGSRSTVDNTGLAQPPPHIPVTPNRGASSRVAVQRGISNGPNPPDTQQLCPGKALQPRFQDDRVTNGVHQEPNTGSSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHLNALGISAVCPDGVGSGLRCSGRLDSVDGPGRSPGRQGDDPIGGRLRKLSIGQYDNDAASQVTFSKCGWGKAGVDPAPSLGSFSSPEDIKETVITAYPSDLNMIDGRIPNSKESSMCLTPSFPVSPETPYVKTSPRYPPFSPPEPQLSSPASLHKGREPRGCPEIISHTVGMSESPVGPKPTMLRADMPATPNFQQVFASSCTVSSNGPGQRRESPPSAERQWVESSPKSTLTLLGNSHPSESPLGTHEFCSSGKDSPGLPCFQSSELQASFHSHELSMSEPQGALPPAGSQTFLGFNTVTTATSVLPPGEDAGTLLVNSHGTSPAPGTPLLTTGAADNGFLPHNFLTVSPGASSHHSPGLQNQNVSLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTMSIPFPNVLPDFCKPSEVASPLPDSPNDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKAPGSFIVRDSHSFRGAYGLAMKVATPPPSVLHLNKKAGDLSNELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAENSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAVQKALSMTLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVSSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKI", "length": 1440 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63HR2-1", "protein_name": "Tensin-2", "gene_name": "TNS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSSGPVERLLRALGRRDSSRAASRPRKAEPHSFREKVFRKKPPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSACQALPPVELRRNTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGNKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYISYFSGLLSGSIRMNSSPLFLHYVLIPMLPAFEPGTGFQPFLKIYQSMQLVYTSGVYHIAGPGPQQLCISLEPALLLKGDVMVTCYHKGGRGTDRTLVFRVQFHTCTIHGPQLTFPKDQLDEAWTDERFPFQASVEFVFSSSPEKIKGSTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGSLTHTRGPLDGSPYAQVQRPPRQTPPAPSPEPPPPPMLSVSSDSGHSSTLTTEPAAESPGRPPPTAAERQELDRLLGGCGVASGGRGAGRETAILDDEEQPTVGGGPHLGVYPGHRPGLSRHCSCRQGYREPCGVPNGGYYRPEGTLERRRLAYGGYEGSPQGYAEASMEKRRLCRSLSEGLYPYPPEMGKPATGDFGYRAPGYREVVILEDPGLPALYPCPACEEKLALPTAALYGLRLEREAGEGWASEAGKPLLHPVRPGHPLPLLLPACGHHHAPMPDYSCLKPPKAGEEGHEGCSYTMCPEGRYGHPGYPALVTYSYGGAVPSYCPAYGRVPHSCGSPGEGRGYPSPGAHSPRAGSISPGSPPYPQSRKLSYEIPTEEGGDRYPLPGHLASAGPLASAESLEPVSWREGPSGHSTLPRSPRDAPCSASSELSGPSTPLHTSSPVQGKESTRRQDTRSPTSAPTQRLSPGEALPPVSQAGTGKAPELPSGSGPEPLAPSPVSPTFPPSSPSDWPQERSPGGHSDGASPRSPVPTTLPGLRHAPWQGPRGPPDSPDGSPLTPVPSQMPWLVASPEPPQSSPTPAFPLAASYDTNGLSQPPLPEKRHLPGPGQQPGPWGPEQASSPARGISHHVTFAPLLSDNVPQTPEPPTQESQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPVEQLVRHFLIETGPKGVKIKGCPSEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVARASSAALSCSPRPTPAVVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGTTSKIFGFVAKKPGSPWENVCHLFAELDPDQPAGAIVTFITKVLLGQRK", "length": 1409 }, "evidence": [ { "id": "HGNC:19737", "url": "https://alliancegenome.org/gene/HGNC:19737#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-101001-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-101001-5#orthology", "database": "AGR" }, { "id": "MGI:2387586", "url": "https://alliancegenome.org/gene/MGI:2387586#orthology", "database": "AGR" }, { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" }, { "id": "RGD:1310917", "url": "https://alliancegenome.org/gene/RGD:1310917#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q68CZ2-1", "protein_name": "Tensin-3", "gene_name": "TNS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEGHGLDLTYITERIIAVSFPAGCSEESYLHNLQEVTRMLKSKHGDNYLVLNLSEKRYDLTKLNPKIMDVGWPELHAPPLDKMCTICKAQESWLNSNLQHVVVIHCRGGKGRIGVVISSYMHFTNVSASADQALDRFAMKKFYDDKVSALMQPSQKRYVQFLSGLLSGSVKMNASPLFLHFVILHGTPNFDTGGVCRPFLKLYQAMQPVYTSGIYNVGPENPSRICIVIEPAQLLKGDVMVKCYHKKYRSATRDVIFRLQFHTGAVQGYGLVFGKEDLDNASKDDRFPDYGKVELVFSATPEKIQGSEHLYNDHGVIVDYNTTDPLIRWDSYENLSADGEVLHTQGPVDGSLYAKVRKKSSSDPGIPGGPQAIPATNSPDHSDHTLSVSSDSGHSTASARTDKTEERLAPGTRRGLSAQEKAELDQLLSGFGLEDPGSSLKEMTDARSKYSGTRHVVPAQVHVNGDAALKDRETDILDDEMPHHDLHSVDSLGTLSSSEGPQSAHLGPFTCHKSSQNSLLSDGFGSNVGEDPQGTLVPDLGLGMDGPYERERTFGSREPKQPQPLLRKPSVSAQMQAYGQSSYSTQTWVRQQQMVVAHQYSFAPDGEARLVSRCPADNPGLVQAQPRVPLTPTRGTSSRVAVQRGVGSGPHPPDTQQPSPSKAFKPRFPGDQVVNGAGPELSTGPSPGSPTLDIDQSIEQLNRLILELDPTFEPIPTHMNALGSQANGSVSPDSVGGGLRASSRLPDTGEGPSRATGRQGSSAEQPLGGRLRKLSLGQYDNDAGGQLPFSKCAWGKAGVDYAPNLPPFPSPADVKETMTPGYPQDLDIIDGRILSSKESMCSTPAFPVSPETPYVKTALRHPPFSPPEPPLSSPASQHKGGREPRSCPETLTHAVGMSESPIGPKSTMLRADASSTPSFQQAFASSCTISSNGPGQRRESSSSAERQWVESSPKPMVSLLGSGRPTGSPLSAEFSGTRKDSPVLSCFPPSELQAPFHSHELSLAEPPDSLAPPSSQAFLGFGTAPVGSGLPPEEDLGALLANSHGASPTPSIPLTATGAADNGFLSHNFLTVAPGHSSHHSPGLQGQGVTLPGQPPLPEKKRASEGDRSLGSVSPSSSGFSSPHSGSTISIPFPNVLPDFSKASEAASPLPDSPGDKLVIVKFVQDTSKFWYKADISREQAIAMLKDKEPGSFIVRDSHSFRGAYGLAMKVATPPPSVLQLNKKAGDLANELVRHFLIECTPKGVRLKGCSNEPYFGSLTALVCQHSITPLALPCKLLIPERDPLEEIAESSPQTAANSAAELLKQGAACNVWYLNSVEMESLTGHQAIQKALSITLVQEPPPVSTVVHFKVSAQGITLTDNQRKLFFRRHYPVNSVIFCALDPQDRKWIKDGPSSKVFGFVARKQGSATDNVCHLFAEHDPEQPASAIVNFVSKVMIGSPKKV", "length": 1445 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BZ33-1", "protein_name": "Tensin-4", "gene_name": "Tns4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSSLLAGGHMVSLTPCEESRMALHPTPSPGLPALCPYYTTESWGTQPLMAPTLRKGSSDRLQQAQQAEARAHCLLQGPGEQASGASQDLESCIDFSLEALNQMILEIDPTFQLLPSGTAGPQAESTNSIMSRNKKEEPEALDIKYIEVTSTRSRYLDGPQRCSSPCATPPFGSPRSGSLFLSRDIPRETRSSSNESLIFSGNQGRGPSPLTPSSLSNAIPCRESRTSGSPLATPPGWEKGLRAPQRGSRVSILSASPVSDVSYVFGSNQSLPHSSLSSYPSSSRSLGSPASSSSSLHSLDRGSQCGRPSDAQAPSNPILGMGQPQAVQSTPVAKEQASSCPASVTNSMADIPIVLINGSPEPQSPPAQRTPGHQDSVQSRVTSPSHLCQAIKSPSKTLPDVPLPASPDGPAKDMQPTMKFVMDTSKYWFKPSITREQAINLLRTEKPGAFVIRDSSSYRGSFGLALKVQETSASAPNRPGEDSSDLIRHFLIESSAKGVHLKGADEEPYFGSLSSFVCQHSIMALALPCKLTIPQKELGGAEPASDSPTHGQTSCLKISAGCHTLYLSSVSVETLSGALAVQKAISVTLERDVLPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLSALRFCGMDPEQRKWQKYCKPSRIFGFVAKSQTEPQENVCHLFAEYDAVQPASQVISLVTALLQDTERM", "length": 696 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CGB6-1", "protein_name": "Tensin-2", "gene_name": "Tns2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSSGPVERLLRALGRRDSSRATSRPRKAEPHSFREKVFRKKTPVCAVCKVTIDGTGVSCRVCKVATHRKCEAKVTSSCQALPPAELRRSTAPVRRIEHLGSTKSLNHSKQRSTLPRSFSLDPLMERRWDLDLTYVTERILAAAFPARPDEQRHRGHLRELAHVLQSKHRDKYLLFNLSEKRHDLTRLNPKVQDFGWPELHAPPLDKLCSICKAMETWLSADPQHVVVLYCKGSKGKLGVIVSAYMHYSKISAGADQALATLTMRKFCEDKVATELQPSQRRYVSYFSGLLSGSIRMNSSPLFLHYVFVPVLPAFEPNTGFQPFLKIYQSMQLVYTSGVYRIAGPGPQQLCISLEPALLLKGDVMVTCYHKGGQGTDRTLVFRVQFHTCTIHGSRLTFPKDQLDEAWADERFPFQASVEFVFSSSPEKVKGNTPRNDPSVSVDYNTTEPAVRWDSYENFNQHHEDSVDGALAHTRGPLDGSPYAQVQRVPRQTPPAPSPELPPPPMLSVSSDSGHSSTLTTEHTAESPGRPPPTAAERQELDRLLGGCGVASAGRGAGRETAILDDEEQPSVGGGLHLGMYSGHRPGLSRRCSCRQGFREPCGVPNGSYYRPEGTLERRRPPYGGYEGHPQGYAEASVEKRRLCRSLSEGPYPYAPELGKPANGDFGYRPAGYREVVILEDPGVPALCSCPACEEKLALPTAALYGLRLEREAAEGWSSEVGKPLLHPVRPGHPLPLLVPACGHHHAPMPDYGCLKPPKVGEEGHEGCSYAVCSEGRYGHSGYPALVTYGYGGAVPSYCPAYGRAPHSCGSPSEGRGYPSPGAHSPRAGSVSPGSPPYLQPRKLGYEISAEDGRDKYPLSGHLASTGPLASTESPEPSWRDGSSGHSTLPRSPRDPQCSASSELSGPSTPLHTSSPVQGKESNRRQDTTRSPSLAPTQRLSPGEALPSVVQGVAEKTPELLTSSRPEQLDPSPFSQTSAPGSPNGWPQERSPGGHTNSASPRSPVPTTLPGLRHAPWQGPRGTSDSPDGSPLTPVPTQMPWLVGSPEPPQSSPTPAFPLATSYDANGPIQPPLPEKRHLPGSGQQPSPPARSTNQHVTFASPLPDVTQPPEHPLQENQSNVKFVQDTSKFWYKPHLSRDQAIALLKDKDPGAFLIRDSHSFQGAYGLALKVATPPPSAQPWKGDPSEQLVRHFLIETGPKGVKIKGCPTEPYFGSLSALVSQHSISPISLPCCLRIPSKDPLEETPEAPVPTNMSTAADLLRQGAACSVLYLTSVETESLTGPQAVAKASSAALSCSPVPVPAIVHFKVSAQGITLTDNQRKLFFRRHYPVNSITFSSTDPQDRRWTNPDGATSKIFGFVAKKPGSPWENVCHLFAELDPDQPASAIVTFITKVLLGQRK", "length": 1400 }, "evidence": [ { "id": "HGNC:19737", "url": "https://alliancegenome.org/gene/HGNC:19737#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-101001-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-101001-5#orthology", "database": "AGR" }, { "id": "MGI:2387586", "url": "https://alliancegenome.org/gene/MGI:2387586#orthology", "database": "AGR" }, { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" }, { "id": "RGD:1310917", "url": "https://alliancegenome.org/gene/RGD:1310917#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZW8-1", "protein_name": "Tensin-4", "gene_name": "TNS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSQVMSSPLLAGGHAVSLAPCDEPRRTLHPAPSPSLPPQCSYYTTEGWGAQALMAPVPCMGPPGRLQQAPQVEAKATCFLPSPGEKALGTPEDLDSYIDFSLESLNQMILELDPTFQLLPPGTGGSQAELAQSTMSMRKKEESEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLRSGGLLLSRDVPRETRSSSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKASSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSHQSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASSCPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLSDAPFTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEEPGAFVIRDSSSYRGSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGADEEPYFGSLSAFVCQHSIMALALPCKLTIPQRELGGADGASDSTDSPASCQKKSAGCHTLYLSSVSVETLTGALAVQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLTTLRFCGMDPEQRKWQKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQPASQVIGLVTALLQDAERM", "length": 715 }, "evidence": [ { "id": "FB:FBgn0000244", "url": "https://alliancegenome.org/gene/FB:FBgn0000244#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HBL0-3", "protein_name": "Tensin-1", "gene_name": "TNS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"https://prosite.expasy.org/PS51182" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2 tensin-type", "eco_id": "ECO_0000259", "start_pos": 295, "end_pos": 421, "start_aa": "Ser", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PKG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKG9" }, { "id": "PS50081", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phorbol-ester/DAG-type", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 91, "start_aa": "Ser", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PKG9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKG9" }, { "id": "PS51181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatase tensin-type", "eco_id": "ECO_0000259", 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}, { "start_pos": 1394, "end_pos": 1396 }, { "start_pos": 173, "end_pos": 175 }, { "start_pos": 294, "end_pos": 296 }, { "start_pos": 611, "end_pos": 613 }, { "start_pos": 705, "end_pos": 707 }, { "start_pos": 863, "end_pos": 865 }, { "start_pos": 940, "end_pos": 942 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PKM7-1", "uniprot_ac": "A0A8M9PKM7", "uniprot_id": "A0A8M9PKM7_DANRE", "mass": { "chemical_mass": 48256.0, "monoisotopic_mass": 48256.0 }, "refseq": { "ac": "XP_021332022", "name": "E3 ubiquitin-protein ligase TRIM69", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332022" }, "gene_names": [ { "name": "si:ch211-114c12.5", "type": "recommended", "evidence": [ { "id": "A0A8M9PKM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKM7" } ] }, { "name": "si:ch211-114c12.5", "type": "synonym", "evidence": [ { "id": "XP_021332022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332022" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase TRIM69", "type": "synonym", "evidence": [ { "id": "XP_021332022", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332022" }, { "id": "A0A8M9PKM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKM7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021332022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332022" } ] } ], "disease": [ { "disease_id": "DOID:0050908", "recommended_name": { "id": "DOID:0050908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets." }, "synonyms": [ { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic syndrome", "description": "A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001)" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "MDS", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "MDS, unclassifiable", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "MDS-U", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "Myelodysplastic Syndromes", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "dysmyelopoietic syndrome", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "hematopoeitic - myelodysplastic syndrome (MDS)", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplasia", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic neoplasm", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic syndrome", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic syndrome, somatic", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic syndrome, unclassifiable", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic syndrome/neoplasm", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic syndromes", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "oligoblastic leukaemia", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "oligoblastic leukemia", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "preleukemia", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "smoldering leukemia", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "smouldering leukaemia", "description": "" }, { "id": "MIM:614286", "resource": "MIM", "url": "https://www.omim.org/entry/614286", "name": "Myelodysplastic syndrome", "description": "Myelodysplastic syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ] }, { "disease_id": "DOID:0080746", "recommended_name": { "id": "DOID:0080746", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080746", "name": "Sweet syndrome", "description": "A skin disease that is characterized by sudden onset of well defined tender plaques or nodules accompanied by fever, arthralgias, ocular inflammation, headaches and, rarely, oral or genital lesions." }, "synonyms": [ { "id": "DOID:0080746", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080746", "name": "Acute Febrile Neutrophilic Dermatosis", "description": "" }, { "id": "DOID:0080746", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080746", "name": "Sweet's syndrome", "description": "" }, { "id": "MONDO:0011959", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011959", "name": "sweet syndrome", "description": "Sweet's syndrome (the eponym for acute febrile neutrophilic dermatosis) is characterized by a constellation of clinical symptoms, physical features, and pathologic findings which include fever, neutrophilia, tender erythematous skin lesions (papules, nodules, and plaques), and a diffuse infiltrate consisting predominantly of mature neutrophils that are typically located in the upper dermis." }, { "id": "MONDO:0011959", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011959", "name": "acute febrile neutrophilic dermatosis", "description": "" }, { "id": "MONDO:0011959", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011959", "name": "sweet syndrome", "description": "" }, { "id": "MONDO:0011959", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011959", "name": "Gomm button disease", "description": "" }, { "id": "MIM:608068", "resource": "MIM", "url": "https://www.omim.org/entry/608068", "name": "Pyrin-associated autoinflammatory disease", "description": "Pyrin-associated autoinflammatory disease" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080746", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080746" } ] }, { "disease_id": "DOID:11123", "recommended_name": { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "IgA vasculitis", "description": "A hypersensitivity vasculitis that is characterized by purpura (purplish plaques), arthralgia, gastrointestinal upset, and/or glomerulonephritis, and may be related to increased immune response following an infection." }, "synonyms": [ { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "Allergic purpura", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "Autoimmune purpura", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "Henoch-Scholein purpura", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "Purpura, autoimmune", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "Henoch-Schoenlein purpura", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "HSP", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "Henoch Schoenlein purpura", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "Henoch Scholein purpura", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "Henoch Schonlein purpura", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "Henoch Schnlein purpura", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "Henoch-Schonlein purpura", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "Henoch-Schnlein purpura", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "IgAV", "description": "" }, { "id": "DOID:11123", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11123", "name": "immunoglobulin A vasculitis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "11123", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11123" } ] }, { "disease_id": "DOID:2841", "recommended_name": { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "asthma", "description": "A bronchial disease that is characterized by chronic inflammation and narrowing of the airways, which is caused by a combination of environmental and genetic factors. The disease has_symptom recurring periods of wheezing (a whistling sound while breathing), has_symptom chest tightness, has_symptom shortness of breath, has_symptom mucus production and has_symptom coughing." }, "synonyms": [ { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "bronchial hyperreactivity", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with acute exacerbation", "description": "" }, { "id": "DOID:2841", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2841", "name": "chronic obstructive asthma with status asthmaticus", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "inherited susceptibility to asthma", "description": "" }, { "id": "MONDO:0010940", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010940", "name": "asthma, nocturnal, susceptibility to", "description": "" }, { "id": "MIM:600807", "resource": "MIM", "url": "https://www.omim.org/entry/600807", "name": "Asthma", "description": "Asthma" } ], "unlinked_id_list": [ "DOID:0080811", "DOID:0080819" ], "evidence": [ { "id": "2841", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2841" } ] }, { "disease_id": "DOID:2987", "recommended_name": { "id": "DOID:2987", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2987", "name": "familial Mediterranean fever", "description": "An autoinflammatory disease characterized by recurrent episodes of fever and acute inflammation of the membranes lining the abdomen, joints and lungs; that has_material_basis_in mutations in the MEFV gene, which encodes the protein pyrin." }, "synonyms": [ { "id": "DOID:2987", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2987", "name": "benign paroxysmal peritonitis", "description": "" }, { "id": "DOID:2987", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2987", "name": "FMF", "description": "" }, { "id": "MONDO:0007601", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007601", "name": "familial Mediterranean fever, autosomal dominant", "description": "" }, { "id": "MONDO:0007601", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007601", "name": "familial Mediterranean fever, AD", "description": "" }, { "id": "MONDO:0007601", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007601", "name": "familial Mediterranean fever, autosomal dominant", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "autosomal recessive familial Mediterranean fever", "description": "Autosomal recessive form of familial Mediterranean fever." }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "autosomal recessive familial Mediterranean fever", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "familial Mediterranean fever, AR", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "familial Mediterranean fever, autosomal recessive", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "FMF", "description": "" }, { "id": "MONDO:0009572", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009572", "name": "familial Mediterranean fever", "description": "" }, { "id": "MIM:134610", "resource": "MIM", "url": "https://www.omim.org/entry/134610", "name": "Familial Mediterranean fever, autosomal dominant", "description": "Familial Mediterranean fever, autosomal dominant" }, { "id": "MIM:249100", "resource": "MIM", "url": "https://www.omim.org/entry/249100", "name": "Familial Mediterranean fever, autosomal recessive", "description": "Familial Mediterranean fever, autosomal recessive" } ], "unlinked_id_list": [], "evidence": [ { "id": "2987", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2987" } ] }, { "disease_id": "DOID:850", "recommended_name": { "id": "DOID:850", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:850", "name": "lung disease", "description": "A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide." }, "synonyms": [], "unlinked_id_list": [ "DOID:9808", "DOID:4765", "DOID:60001", "DOID:3683" ], "evidence": [ { "id": "850", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:850" } ] }, { "disease_id": "DOID:9119", "recommended_name": { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells." }, "synonyms": [ { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "AML - acute Myeloid Leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "Leukemia, Myelocytic, acute", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloblastic leukaemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloblastic leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myelogenous leukaemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myelogenous leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloid leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia", "description": "Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections." }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML - acute myeloid leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML - acute myeloid leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "ANLL", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute Nonlymphocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute Nonlymphocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute granulocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute granulocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloblastic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelogenous leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelogenous leukemias", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukaemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute nonlymphocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute nonlymphocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "hematopoeitic - acute Myleogenous leukaemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "hematopoeitic - acute Myleogenous leukemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, reduced survival in, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, myelocytic, acute", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "myeloid leukemia, acute", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "myeloid leukemia, acute, M4/M4Eo subtype, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute non lymphoblastic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute non lymphoblastic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid", "description": "" }, { "id": "MIM:601626", "resource": "MIM", "url": "https://www.omim.org/entry/601626", "name": "Leukemia, acute myelogenous", "description": "Leukemia, acute myelogenous" } ], "unlinked_id_list": [], "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ] }, { "disease_id": "DOID:9538", "recommended_name": { "id": "DOID:9538", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9538", "name": "multiple myeloma", "description": "A myeloid neoplasm that is located_in the plasma cells in bone marrow." }, "synonyms": [ { "id": "DOID:9538", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9538", "name": "myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "plasma cell myeloma", "description": "A bone marrow-based plasma cell neoplasm characterized by a serum monoclonal protein and skeletal destruction with osteolytic lesions, pathological fractures, bone pain, hypercalcemia, and anemia. Clinical variants include non-secretory myeloma, smoldering myeloma, indolent myeloma, and plasma cell leukemia. (WHO, 2001)" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "Kahler disease", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "Kahler's disease", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "Multiple Myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "medullary plasmacytoma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma, resistance to, Somatic mutation", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma, susceptibility to, Somatic mutation", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "multiple myeloma/plasma cell myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloid neoplasm of plasma cell", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma, multiple", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma, plasma cell, malignant", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myelomatosis", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "plasma cell myeloid neoplasm", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "plasma cell myeloma", "description": "" }, { "id": "MONDO:0009693", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009693", "name": "myeloma - multiple", "description": "" }, { "id": "MIM:254500", "resource": "MIM", "url": "https://www.omim.org/entry/254500", "name": "Multiple myeloma", "description": "Multiple myeloma" } ], "unlinked_id_list": [], "evidence": [ { "id": "9538", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9538" } ] }, { "disease_id": "DOID:9952", "recommended_name": { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "acute lymphoblastic leukemia", "description": "A acute leukemia that is characterized by over production of lymphoblasts." }, "synonyms": [ { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "acute lymphoblastic leukaemia", "description": "" }, { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "acute lymphocytic leukaemia", "description": "" }, { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "ALL", "description": "" }, { "id": "DOID:9952", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9952", "name": "precursor lymphoblastic lymphoma/leukemia", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "lymphoblastic leukemia, acute, with lymphomatous features", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "leukemia, acute lymphoblastic", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "lymphoblastic leukemia, acute, with lymphomatous features", "description": "" }, { "id": "MONDO:0009539", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009539", "name": "lall", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphocytic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "T-cell acute lymphoblastic leukemia, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, T-cell acute lymphoblastic, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, T-cell acute lymphocytic, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphoblastic, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphocytic, Philadelphia chromosome positive, somatic", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphocytic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "ALL", "description": "" }, { "id": "MONDO:0013108", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013108", "name": "leukemia, acute lymphoblastic", "description": "" }, { "id": "MIM:613065", "resource": "MIM", "url": "https://www.omim.org/entry/613065", "name": "Leukemia, acute lymphoblastic", "description": "Leukemia, acute lymphoblastic" } ], "unlinked_id_list": [ "DOID:0080638", "DOID:5604" ], "evidence": [ { "id": "9952", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9952" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKM7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKM7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-114c12.5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKM7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-13", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PKM7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PKM7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd13733", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13733", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "565476", "url": "https://www.ncbi.nlm.nih.gov/gene/565476", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein 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"OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021332022", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332022", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PKM7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PKM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-13", "url": "https://zfin.org/ZDB-GENE-060526-13", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKKSILKANRYEAPEAGLSNSIGAVTWTLPDEGLQAHSSVPSKSSQSPRQKDLKDLRSLQECVKFITQWKQQVDQVCKPGANADEGPGASVLAEPRSLEQCRKLILEWAQELRKVDSLFSEGTWRKERDTSWEQKESQADSAKHMEQKIMEWAKELQAVSERCGVMRQELAQFLKQLELKKRKILTLLPFLEFITWSLLKQDSQGVVPQLWLLSKHRTWKTETPKYIPNSVWRWIRSASVDISLDPMTNHPWLQLSDDKKKVQEALSETEVSFSKQRFDSWPCVLGWEGLTSGRYYWEVDIANKGYWRIGVTTASSKRHGRSPMNPSEGFWTIWKSTRQFYACTKPETELPLTLVPKKLGVYLDYEEGQVSFYNVETRTHIFTFTANFRETLFPLFAPLDGRTLITLSTAEVNPETASL", "length": 419, "header": "tr|A0A8M9PKM7-1|A0A8M9PKM7_DANRE Isoform 1 of E3 ubiquitin-protein ligase TRIM69 OS=Danio rerio OX=7955 GN=si:ch211-114c12.5 PE=4 SV=1 CANONICAL=A0A8M9PKM7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PKM7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKM7/entry#A0A8M9PKM7-1", "sequence": { "sequence": "MKKSILKANRYEAPEAGLSNSIGAVTWTLPDEGLQAHSSVPSKSSQSPRQKDLKDLRSLQECVKFITQWKQQVDQVCKPGANADEGPGASVLAEPRSLEQCRKLILEWAQELRKVDSLFSEGTWRKERDTSWEQKESQADSAKHMEQKIMEWAKELQAVSERCGVMRQELAQFLKQLELKKRKILTLLPFLEFITWSLLKQDSQGVVPQLWLLSKHRTWKTETPKYIPNSVWRWIRSASVDISLDPMTNHPWLQLSDDKKKVQEALSETEVSFSKQRFDSWPCVLGWEGLTSGRYYWEVDIANKGYWRIGVTTASSKRHGRSPMNPSEGFWTIWKSTRQFYACTKPETELPLTLVPKKLGVYLDYEEGQVSFYNVETRTHIFTFTANFRETLFPLFAPLDGRTLITLSTAEVNPETASL", "length": 419, "header": "tr|A0A8M9PKM7-1|A0A8M9PKM7_DANRE Isoform 1 of E3 ubiquitin-protein ligase TRIM69 OS=Danio rerio OX=7955 GN=si:ch211-114c12.5 PE=4 SV=1 CANONICAL=A0A8M9PKM7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:565476", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565476", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9PX13-1", "protein_name": "E3 ubiquitin-protein ligase TRIM15", "gene_name": "si:dkey-219e21.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGEQTKPYKSILKDNTLKVPQISNQGQQSNSIGAVRWVLPDEEVQVHSSAPTIPYKSNSGFSTRSQQRQRQQGLKDLRSLDECIQFINRWKQQVAQVCKNEDDPGEGSSRPTKTDSRTERSLEESRKLILQWANELQSVDKLSKKQPWLKERIDLEEEDDKTKLDKSEGDEVQERITEWAKEIQSVSESCGMPGDELAQMLRLLGLRKKRLATLMPLLEFITWSLLKEESKGMVPHLWLSAKQRTWKAGISRYIPNSVWSWIVSAGADVSLDPMTNNPWLYVSEDHKKIQEGLIEANLPYSSQRFDSLPCVLGWEGYMSGRHYWEVEFANNGYWRVGVTTASSKRHGRFPMNPSSGYWVLWRSTRQFFACTNPETPLPQELVPRRMGIYIDYEEGQISFYNADNKSHIYTFTGHFREKLYPFFSLMDGRTLMTLWSPKEHSHF", "length": 443 }, "evidence": [ { "id": "RGD:61889", "url": "https://alliancegenome.org/gene/RGD:61889#orthology", "database": "AGR" }, { "id": "MGI:1859396", "url": "https://alliancegenome.org/gene/MGI:1859396#orthology", "database": "AGR" }, { "id": "HGNC:6998", "url": "https://alliancegenome.org/gene/HGNC:6998#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HIZ5-1", "protein_name": "Zinc-binding protein A33 isoform X1", "gene_name": "si:ch73-54f23.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRSQSSDCFVLTRKTGMHTNHMKDTNNNFNNSLLGAQKEKLIQAIKKIKHEIDECYEAEKDAFVDALEVENRFEKIEREIRAEFQNLHRFLNEEEEADVERLKKERDKRVKILKDREKKIAMQGRDLEKAIETLNCKLREDDSPKLLKEIKELLKRCEVNFVRPSPIDSEIFSSQFVGPIQYRIWKHMKPSLYPNISLLTFDPETAHPLLTLSPERTAVTFEEGKETGENAAERNPKRFHYYYCVMGSEGFTHGRHYWEVEVKGKTAWRVGVARADVHRGEMDSSSTLNGLWTLSLRNGSITACTHPKPTPVLSYTPPIRIGVFLDCDNEEVSFYNAVTMNPLFSFYTGTVLVPLYPFYNPCDTDEGKNCAPLSIFHPSL", "length": 380 }, "evidence": [ { "id": "RGD:61889", "url": "https://alliancegenome.org/gene/RGD:61889#orthology", "database": "AGR" }, { "id": "MGI:1859396", "url": "https://alliancegenome.org/gene/MGI:1859396#orthology", "database": "AGR" }, { "id": "HGNC:6998", "url": "https://alliancegenome.org/gene/HGNC:6998#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O15553-2", "protein_name": "Pyrin", "gene_name": "MEFV", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKTPSDHLLSTLEELVPYDFEKFKFKLQNTSVQKEHSRIPRSQIQRARPVKMATLLVTYYGEEYAVQLTLQVLRAINQRLLAEELHRAAIQEYSTQENGTDDSAASSSLGENKPRSLKTPDHPEGNEGNGPRPYGGGAASLRCSQPEAGRGLSRKPLSKRREKASEGLDAQGKPRTRSPALPGGRSPGPCRALEGGQAEVRLRRNASSAGRLQGLAGGAPGQKECRPFEVYLPSGKMRPRSLEVTISTGEKAPANPEILLTLEEKTAANLDSATEPRARPTPDGGASADLKEGPGNPEHSVTGRPPDTAASPRCHAQEGDPVDGTCVRDSCSFPEAVSGHPQASGSRSPGCPRCQDSHERKSPGSLSPQPLPQCKRHLKQVQLLFCEDHDEPICLICSLSQEHQGHRVRPIEEVALEHKKKIQKQLEHLKKLRKSGEEQRSYGEEKAVSFLKQTEALKQRVQRKLEQVYYFLEQQEHFFVASLEDVGQMVGQIRKAYDTRVSQDIALLDALIGELEAKECQSEWELLQDIGDILHRAKTVPVPEKWTTPQEIKQKIQLLHQKSEFVEKSTKYFSETLRSEMEMFNVPELIGAQAHAVNVILDAETAYPNLIFSDDLKSVRLGNKWERLPDGPQRFDSCIIVLGSPSFLSGRRYWEVEVGDKTAWILGACKTSISRKGNMTLSPENGYWVVIMMKENEYQASSVPPTRLLIKEPPKRVGIFVDYRVGSISFYNVTARSHIYTFASCSFSGPLQPIFSPGTRDGGKNTAPLTICPVGGQGPD", "length": 781 }, "evidence": [ { "id": "RGD:61889", "url": "https://alliancegenome.org/gene/RGD:61889#orthology", "database": "AGR" }, { "id": "MGI:1859396", "url": "https://alliancegenome.org/gene/MGI:1859396#orthology", "database": "AGR" }, { "id": "HGNC:6998", "url": "https://alliancegenome.org/gene/HGNC:6998#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-13#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJ25-1", "protein_name": "Pyrin", "gene_name": "Mefv", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANTRVDHLLNTLEELLPYELEKFKFKLHTTSLEKGHSRIPLSLVKMARPIKLTRLLLTYYGEEYAVRLTLQILRATNQRQLAEELHKATGPEHLTEENGVGGSVQSSAENKDKGVKGSDVPGEDEAQQNDDESDILPPIQAEVGKGPQKKSLAKRKDQRGPESLDSQTKPGARSAAPLYRRTLVTQSPGDKENRAGAQPQECQLCREAARSTAMSQGGERSRRLKCICLQERSDPGVLKLPLTQKKENPQIQKLFRLKRKQEMAVSFVREATLNGRTTGTLEKGVGIPEHSMMLDEETSRNMSSKISLTREKRCTASWTENGNGGPETPETLGETVSSILCDSCSPKVLLSLGEKLAQTPEDPASLGQAASKGRSRDKVACPLCHTQGELPAKACVQSSCSCSVAPGDPKASGRHSICFQCQSSRAGKSCEAQSPQFLPQCPRHMKQVQLLFCEDHREPICLICRLSQEHQGHRVRPIEEAALQYKEQIRKQLERLREMRGYVEEHKLPADKKAEDFLKQTETQKQRISCPLEKLFQFLEQQEQLFVTWLQELVQTIGKVRETYYTQVSLLDKLIGELEAKQDQPEWELMQDIGATLHRAETMTASELLGIPPGVKEKLHLLYQKSKSAEKNMQRFSEMLGSEMAFSASDVATREGCRPSTTKAQALIPTVHLKCDGAHTQDFDVILCAELEAGGSEPQDYLHPSSAQDTPELHEIHSQNNKRKFKSFLKWKPSFSRTDRCLRTCW", "length": 747 }, "evidence": [ { "id": "RGD:61889", "url": "https://alliancegenome.org/gene/RGD:61889#orthology", "database": "AGR" }, { "id": "MGI:1859396", "url": "https://alliancegenome.org/gene/MGI:1859396#orthology", "database": "AGR" }, { "id": "HGNC:6998", "url": "https://alliancegenome.org/gene/HGNC:6998#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-13#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JJ26-1", "protein_name": "Pyrin", "gene_name": "Mefv", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKTLGDHLLNTLEELLPYDFEKFKFKLQNTSLEKGHSKIPRGHMQMARPVKLASLLITYYGEEYAVRLTLQILRATNQRQLAEELRKATGTEHLIEENRVGGSVQSSVENKAKSVKVPDVPEGDGTQQNNDESDTLPSSQAEVGKGPQKKSLTKRKDQRGPESLDSQTKPWTRSTAPLYRRTQGTQSPGDKESTASAQLRRNVSSAGRLQGLYNNAPGRRESKKAEVYVYLPSGKKRPRSLEITTYSREGEPPNSEVLPTQEETRNGSLIRMRTATLNGRTTGALEKGTGIPEHSMVLDEKTFRNMSSKTSLIGEERCPTSWTENGNGSPETTESSGETAGSILSDPEVPLSLCEKPAKTPEDPASLGQAACEGRSQDKAVCPLCHTQEGDLRGDTCVQSSCSCSIAPGDPKASGRCSICFQCQGLLARKSCEAQSPQSLPQCPRHMKQVLLLFCEDHREPICLICRLSLEHQGHRVRPIEEAALEYKEQIREQLERLREMRGYVEEHRLQGDKKTDDFLKQTEIQKQKISCPLEKLYQLLEKQEQLFVTWLQELSQTISKVRETYYTRVSLLDEMIEELEAKQDQPEWDLMQDIGITLHRAKMMSASELLDTPPGVKEKLHLLYQKSKSVEKNMQCFSEMLSSEMAFSASDVAKWEGRQPSATQVQGLVPTVHLKCDGAHTQDCDVVFYPEREAGGSEPKDYLHPQPAQDTPELHEIHSRNNKRKFKSFLKWKPSFSRTDWRLRTCCYRDLDQAAAHPNLIFSMI", "length": 767 }, "evidence": [ { "id": "RGD:61889", "url": "https://alliancegenome.org/gene/RGD:61889#orthology", "database": "AGR" }, { "id": "MGI:1859396", "url": "https://alliancegenome.org/gene/MGI:1859396#orthology", "database": "AGR" }, { "id": "HGNC:6998", "url": "https://alliancegenome.org/gene/HGNC:6998#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-13#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKM7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKM7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKM7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKM7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, 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"MVTKDNSGSSSKTTCVKKQKCIMNNSQKAGKVHRDPQKSIFEPELTLKVTADDGGSKTSPTENGVIESTNEWSTSNLHSLKEMQYLQHEAEDSLIDASLDMDKSSLMGFIDSSNLESSEDVRTVPCFQVDVKTDVVLIDEDDDDMSLRERTVTDVSTTDGNAAELVCGGLQSISSDSSHSVCEGRSQEQATPIEPSHEEPLKKQKRSCCLCVII", "length": 214, "header": "tr|A0A8M9PKS8-1|A0A8M9PKS8_DANRE Isoform 1 of Uncharacterized protein si:ch211-12e13.12 OS=Danio rerio OX=7955 GN=si:ch211-12e13.12 PE=4 SV=1 CANONICAL=A0A8M9PKS8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100148072", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148072", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKS8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKS8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 24, "end_pos": 26 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PKV9-1", "uniprot_ac": "A0A8M9PKV9", "uniprot_id": "A0A8M9PKV9_DANRE", "mass": { "chemical_mass": 95218.0, "monoisotopic_mass": 95218.0 }, "refseq": { "ac": "XP_021325534", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325534" }, "gene_names": [ { "name": "LOC110438308", "type": "recommended", "evidence": [ { "id": "A0A8M9PKV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKV9" } ] }, { "name": "LOC101886669", "type": "synonym", "evidence": [ { "id": "A0A8M9PKV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKV9" } ] }, { "name": "LOC110438308", "type": "synonym", "evidence": [ { "id": "XP_021325534", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325534" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PKV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKV9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325534", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325534" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325534" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PKV9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKV9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438308", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKV9", "locus": {} } ], "crossref": [ { "id": "A0A8M9PKV9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PKV9", "database": "AlphaFoldDB", "categories": [] }, { "id": "101886669", "url": "https://www.ncbi.nlm.nih.gov/gene/101886669", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "110438308", "url": "https://www.ncbi.nlm.nih.gov/gene/110438308", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:110438308", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438308", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PKV9", "url": "https://www.orthodb.org/?gene=A0A8M9PKV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33480", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33480", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33480:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33480:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_021325534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325534", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PKV9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PKV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IN65", "url": "https://www.uniprot.org/uniprotkb/A0AC58IN65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IN65-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IN65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IN70", "url": "https://www.uniprot.org/uniprotkb/A0AC58IN70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IN70-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IN70-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSEGQDDKSDRYSGCTEFAVDEVTACAKEETKLNKKILGYASEESSSRSDISEDDYVPDTEESDSNTSEKVESLVKKISNNKKKVKSTSNVPACKKRRVSPSQSSASDKQDSSLQSSSSGEHEESHSPNNLNVNVMMLKKKKDGARLYNKKFYCLFCFKPFSKIARHLESKHKDKPEVARAIAFPKGSKERKIQLSLLRNKGNRCHNAQVLSEGRGTVIPKQQSTVPVNASDYLHCINCSAYLKRKSLWRHMQRCQLSQKINKMKPGKTRVQSLCSYAEPVPDSISERFWKMVLDMHDDEITHVVRKEKIILKLGQHLFNKHGHDVTKHEYIRQKMRETGRLVLEGKKNGKLKEVSDFFIPANFPYVIQAVHSVAGLNEETSTFKTPSLALKLGHNLKKMASIIECDAMMADDKNSLSNVQAFKQICDTKWSECVSSQALRNLSEVKWNCPQLLPFAEDVKKMHQYLDSQSKAYQARLEEEQSMKHWAELAKVTLCQVILFNRRREGEVSKMSLNSFTLRDTSSTHPDVELALSDLEKSLCSHFQRIEVRGKRGRKVPILLTPNMVVSMELLVKTRRSCDVPDENVFMFGRPQALTFFRGSDVIRNIAKSCGAKHPEALSSTKLRKHMATMSKVLNLKENEMDNLADFLGHDIRVHRQYYRLPEGTLQLAKISKVLMAMERGQLSQFKGQNLDEIQIDPQEKLLLDSDGSESENEIESTGNGASPSNSAEKSKKSAEVGQHQEPSKGGKNSKKLQPTSKDLQEPHRTKRSSQNERRRWSLEEIKAVEKTMMEFIMSGKVPGKAQCMNCIESSPAALQNRSWEGVKFYVKNRIDSLKKKL", "length": 839, "header": "tr|A0A8M9PKV9-1|A0A8M9PKV9_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110438308 PE=4 SV=1 CANONICAL=A0A8M9PKV9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PKV9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKV9/entry#A0A8M9PKV9-1", "sequence": { "sequence": "MSEGQDDKSDRYSGCTEFAVDEVTACAKEETKLNKKILGYASEESSSRSDISEDDYVPDTEESDSNTSEKVESLVKKISNNKKKVKSTSNVPACKKRRVSPSQSSASDKQDSSLQSSSSGEHEESHSPNNLNVNVMMLKKKKDGARLYNKKFYCLFCFKPFSKIARHLESKHKDKPEVARAIAFPKGSKERKIQLSLLRNKGNRCHNAQVLSEGRGTVIPKQQSTVPVNASDYLHCINCSAYLKRKSLWRHMQRCQLSQKINKMKPGKTRVQSLCSYAEPVPDSISERFWKMVLDMHDDEITHVVRKEKIILKLGQHLFNKHGHDVTKHEYIRQKMRETGRLVLEGKKNGKLKEVSDFFIPANFPYVIQAVHSVAGLNEETSTFKTPSLALKLGHNLKKMASIIECDAMMADDKNSLSNVQAFKQICDTKWSECVSSQALRNLSEVKWNCPQLLPFAEDVKKMHQYLDSQSKAYQARLEEEQSMKHWAELAKVTLCQVILFNRRREGEVSKMSLNSFTLRDTSSTHPDVELALSDLEKSLCSHFQRIEVRGKRGRKVPILLTPNMVVSMELLVKTRRSCDVPDENVFMFGRPQALTFFRGSDVIRNIAKSCGAKHPEALSSTKLRKHMATMSKVLNLKENEMDNLADFLGHDIRVHRQYYRLPEGTLQLAKISKVLMAMERGQLSQFKGQNLDEIQIDPQEKLLLDSDGSESENEIESTGNGASPSNSAEKSKKSAEVGQHQEPSKGGKNSKKLQPTSKDLQEPHRTKRSSQNERRRWSLEEIKAVEKTMMEFIMSGKVPGKAQCMNCIESSPAALQNRSWEGVKFYVKNRIDSLKKKL", "length": 839, "header": "tr|A0A8M9PKV9-1|A0A8M9PKV9_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110438308 PE=4 SV=1 CANONICAL=A0A8M9PKV9-1" }, "locus": {} }, { "isoform_ac": "A0AC58IN65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKV9/entry#A0AC58IN65-1", "sequence": { "sequence": "MSEGQDDKSDRYSGCTEFAVDEVTACAKEETKRNFCWTVMDPSLKMRLSQLEMVPHLQIQQRNQRSLLRLDNTKNHPKEARILKNCSRLARTCRNRTEQRDLHKTSEEGGLWRRSRPWRRQ", "length": 121, "header": "tr|A0AC58IN65-1|A0AC58IN65_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC110438308 PE=4 SV=1 CANONICAL=A0A8M9PKV9-1" }, "locus": {} }, { "isoform_ac": "A0AC58IN70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PKV9/entry#A0AC58IN70-1", "sequence": { "sequence": "MSEGQDDKSDRYSGCTEFAVDEVTACAKEETKRNQRSLLRLDNTKNHPKEARILKNCSRLARTCRNRTEQRDLHKTSEEGGLWRRSRPWRRQ", "length": 92, "header": "tr|A0AC58IN70-1|A0AC58IN70_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=LOC110438308 PE=4 SV=1 CANONICAL=A0A8M9PKV9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110438308", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438308", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 229, "end_pos": 231, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 818, "end_pos": 820, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 229, "end_pos": 231 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 442, "end_pos": 444 }, { "start_pos": 66, "end_pos": 68 }, { "start_pos": 818, "end_pos": 820 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PL05-1", "uniprot_ac": "A0A8M9PL05", "uniprot_id": "A0A8M9PL05_DANRE", "mass": { "chemical_mass": 176045.0, "monoisotopic_mass": 176045.0 }, "refseq": { "ac": "XP_021325584", "name": "synaptonemal complex protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325584" }, "gene_names": [ { "name": "sycp2", "type": "recommended", "evidence": [ { "id": "A0A8M9PL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL05" } ] }, { "name": "sycp2", "type": "synonym", "evidence": [ { "id": "XP_021325584", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325584" } ] } ], "protein_names": [ { "name": "Synaptonemal complex protein 2", "type": "synonym", "evidence": [ { "id": "A0A8M9PL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL05/entry#names_and_taxonomy" } ] }, { "name": "synaptonemal complex protein 2", "type": "synonym", "evidence": [ { "id": "XP_021325584", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325584" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021325584.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325584", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325584" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL05", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL05" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sycp2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL05", "locus": {} } ], "crossref": [ { "id": "557000", "url": "https://www.ncbi.nlm.nih.gov/gene/557000", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024835", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024835", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:557000", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557000", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PL05", "url": "https://www.orthodb.org/?gene=A0A8M9PL05", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15607", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15607", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15607:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15607:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF18581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18584", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18584", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325584", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325584", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PL05", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL05", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PL05-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL05-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"length": 1569, "header": "tr|A0A8M9PL05-1|A0A8M9PL05_DANRE Isoform 1 of Synaptonemal complex protein 2 OS=Danio rerio OX=7955 GN=sycp2 PE=3 SV=2 CANONICAL=A0A8M9PL05-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1004, "start_aa": "Thr", "end_pos": 1004, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1004", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 552, "start_aa": "Thr", "end_pos": 552, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr552", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:557000", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557000", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL05", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL05" } ], "pmid": "" }, { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL05", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL05" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1067, "end_pos": 1069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1108, "end_pos": 1110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1212, "end_pos": 1214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1359, "end_pos": 1361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 414, "end_pos": 416, "annotation": "n_glycosylation_sequon" }, { "start_pos": 529, "end_pos": 531, "annotation": "n_glycosylation_sequon" }, { "start_pos": 540, "end_pos": 542, "annotation": "n_glycosylation_sequon" }, { "start_pos": 649, "end_pos": 651, "annotation": "n_glycosylation_sequon" }, { "start_pos": 739, "end_pos": 741, "annotation": "n_glycosylation_sequon" }, { "start_pos": 745, "end_pos": 747, "annotation": "n_glycosylation_sequon" }, { "start_pos": 783, "end_pos": 785, "annotation": "n_glycosylation_sequon" }, { "start_pos": 806, "end_pos": 808, "annotation": "n_glycosylation_sequon" }, { "start_pos": 839, "end_pos": 841, "annotation": "n_glycosylation_sequon" }, { "start_pos": 849, "end_pos": 851, "annotation": "n_glycosylation_sequon" }, { "start_pos": 879, "end_pos": 881, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL05" }, { "id": "PF18584", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18584" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Synaptonemal complex protein 2 Spt16M-like", "eco_id": "ECO_0000259", "start_pos": 280, "end_pos": 394, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PL05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL05" }, { "id": "PF18581", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18581" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Synaptonemal complex protein 2 armadillo-repeat-like", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 185, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 552, 1004 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1067, "end_pos": 1069 }, { "start_pos": 1108, "end_pos": 1110 }, { "start_pos": 1212, "end_pos": 1214 }, { "start_pos": 1359, "end_pos": 1361 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 414, "end_pos": 416 }, { "start_pos": 529, "end_pos": 531 }, { "start_pos": 540, "end_pos": 542 }, { "start_pos": 649, "end_pos": 651 }, { "start_pos": 739, "end_pos": 741 }, { "start_pos": 745, "end_pos": 747 }, { "start_pos": 783, "end_pos": 785 }, { "start_pos": 806, "end_pos": 808 }, { "start_pos": 839, "end_pos": 841 }, { "start_pos": 849, "end_pos": 851 }, { "start_pos": 879, "end_pos": 881 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PL07-1", "uniprot_ac": "A0A8M9PL07", "uniprot_id": "A0A8M9PL07_DANRE", "mass": { "chemical_mass": 85300.0, "monoisotopic_mass": 85300.0 }, "refseq": { "ac": "XP_021332152", "name": "rab-like protein 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332152" }, "gene_names": [ { "name": "rabl6b", "type": "recommended", "evidence": [ { "id": "A0A8M9PL07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL07" } ] }, { "name": "rabl6b", "type": "synonym", "evidence": [ { "id": "XP_021332152", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332152" } ] } ], "protein_names": [ { "name": "Rab-like protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PL07", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL07/entry#names_and_taxonomy" } ] }, { "name": "rab-like protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021332152", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332152" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021332152", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332152" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL07", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL07" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rabl6b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL07", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-97", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-97", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PL07", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PL07", "database": "AlphaFoldDB", "categories": [] }, { "id": "100003036", "url": "https://www.ncbi.nlm.nih.gov/gene/100003036", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100003036", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003036", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PL07", "url": "https://www.orthodb.org/?gene=A0A8M9PL07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14932:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14932:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08477", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08477", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021332152", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332152", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PL07", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PL07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PYM8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PYM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PYM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PYM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-97", "url": "https://zfin.org/ZDB-GENE-081104-97", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFSALKKLVGSEPVGPIKDKNIPAGLQSMNQSLQRRFAKGVQYNMKIVIRGDRNTGKSTLWHRLQGKKFQEEYIPTQEIQVTSIHWNYKTTDDVVKVEVWDVVDKGQKIPLPEGVGKGKKKSEALKLENEPQEQAESELALDAEFLDVYKNCNGVIMMFDITKQWTYNYILRELPKVPTHVPVCVLGNYRDMGEHRVVLPDDIRDFITGLNRPLGSSYIHYAESSMKNGFGLKYLHRFFNIPFLQLQRETLLRQLETNQLDIDATLEELSVQQETEDQNYDIFLEMNDSRSKGYNSPGPANGQSPSSGSQSPVVPQSGCSTSSSSPCSPQQPPIPSQKSPSPSPSPPPPPLSTSQAPAASPSPSPSPAHPGPAVSAAQAPAPQNQKRSFISRLFGSVSTQDPPAVAQEPDPVSEAAPPTVQSVDDFVPDEGIDKSFLEDSLPSNTRAAMNTQPSAAAGTADSDSEGEGREGNPMVAGFQDDLDPDDAEIKPKAAISSKDLDITLSSDEEVPRPSVAQDEDLDPQTHLATLDSLSLEDKPKPVSREPLIQTQEIIISSQKAETSILTPTPLHTTPALQTASAHPQEQAVKAKPSSAQAESSDSDPDVPVAEQMLSFVMDDPDFDSEEEVVQKVSQESFPVRDDLPDLSDDDLTAAKIPEPMKPAVLSFKSKNDGDLFGLGIEEKSIKSKDSSDEQEENKHSKEKKKKKKKSKEDDDKSSKKKHKHKKKERDETGGALDEKEKRKRKSRSKKTDDLEAFLGGEEEASAKREEGDYEEL", "length": 776, "header": "tr|A0A8M9PL07-1|A0A8M9PL07_DANRE Isoform 1 of Rab-like protein 6 isoform X1 OS=Danio rerio OX=7955 GN=rabl6b PE=4 SV=1 CANONICAL=A0A8M9PL07-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PL07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL07/entry#A0A8M9PL07-1", "sequence": { "sequence": "MFSALKKLVGSEPVGPIKDKNIPAGLQSMNQSLQRRFAKGVQYNMKIVIRGDRNTGKSTLWHRLQGKKFQEEYIPTQEIQVTSIHWNYKTTDDVVKVEVWDVVDKGQKIPLPEGVGKGKKKSEALKLENEPQEQAESELALDAEFLDVYKNCNGVIMMFDITKQWTYNYILRELPKVPTHVPVCVLGNYRDMGEHRVVLPDDIRDFITGLNRPLGSSYIHYAESSMKNGFGLKYLHRFFNIPFLQLQRETLLRQLETNQLDIDATLEELSVQQETEDQNYDIFLEMNDSRSKGYNSPGPANGQSPSSGSQSPVVPQSGCSTSSSSPCSPQQPPIPSQKSPSPSPSPPPPPLSTSQAPAASPSPSPSPAHPGPAVSAAQAPAPQNQKRSFISRLFGSVSTQDPPAVAQEPDPVSEAAPPTVQSVDDFVPDEGIDKSFLEDSLPSNTRAAMNTQPSAAAGTADSDSEGEGREGNPMVAGFQDDLDPDDAEIKPKAAISSKDLDITLSSDEEVPRPSVAQDEDLDPQTHLATLDSLSLEDKPKPVSREPLIQTQEIIISSQKAETSILTPTPLHTTPALQTASAHPQEQAVKAKPSSAQAESSDSDPDVPVAEQMLSFVMDDPDFDSEEEVVQKVSQESFPVRDDLPDLSDDDLTAAKIPEPMKPAVLSFKSKNDGDLFGLGIEEKSIKSKDSSDEQEENKHSKEKKKKKKKSKEDDDKSSKKKHKHKKKERDETGGALDEKEKRKRKSRSKKTDDLEAFLGGEEEASAKREEGDYEEL", "length": 776, "header": "tr|A0A8M9PL07-1|A0A8M9PL07_DANRE Isoform 1 of Rab-like protein 6 isoform X1 OS=Danio rerio OX=7955 GN=rabl6b PE=4 SV=1 CANONICAL=A0A8M9PL07-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PYM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL07/entry#A0A8M9PYM8-1", "sequence": { "sequence": "MFSALKKLVGSEPVGPIKDKNIPAGLQSMNQSLQRRFAKGVQYNMKIVIRGDRNTGKSTLWHRLQGKKFQEEYIPTQEIQVTSIHWNYKTTDDVVKVEVWDVVDKGKGKKKSEALKLENEPQEQAESELALDAEFLDVYKNCNGVIMMFDITKQWTYNYILRELPKVPTHVPVCVLGNYRDMGEHRVVLPDDIRDFITGLNRPLGSSYIHYAESSMKNGFGLKYLHRFFNIPFLQLQRETLLRQLETNQLDIDATLEELSVQQETEDQNYDIFLEMNDSRSKGYNSPGPANGQSPSSGSQSPVVPQSGCSTSSSSPCSPQQPPIPSQKSPSPSPSPPPPPLSTSQAPAASPSPSPSPAHPGPAVSAAQAPAPQNQKRSFISRLFGSVSTQDPPAVAQEPDPVSEAAPPTVQSVDDFVPDEGIDKSFLEDSLPSNTRAAMNTQPSAAAGTADSDSEGEGREGNPMVAGFQDDLDPDDAEIKPKAAISSKDLDITLSSDEEVPRPSVAQDEDLDPQTHLATLDSLSLEDKPKPVSREPLIQTQEIIISSQKAETSILTPTPLHTTPALQTASAHPQEQAVKAKPSSAQAESSDSDPDVPVAEQMLSFVMDDPDFDSEEEVVQKVSQESFPVRDDLPDLSDDDLTAAKIPEPMKPAVLSFKSKNDGDLFGLGIEEKSIKSKDSSDEQEENKHSKEKKKKKKKSKEDDDKSSKKKHKHKKKERDETGGALDEKEKRKRKSRSKKTDDLEAFLGGEEEASAKREEGDYEEL", "length": 766, "header": "tr|A0A8M9PYM8-1|A0A8M9PL07_DANRE Computationally mapped isoform of Rab-like protein 6 isoform X1 OS=Danio rerio OX=7955 GN=rabl6b PE=4 SV=1 CANONICAL=A0A8M9PL07-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100003036", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003036", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32TW06-1", "protein_name": "Rab-like protein 6 isoform X1", "gene_name": "rabl6a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFTALKKLVGSEAVQLRDRNIPAGLQSMNQSLQRRFAKGVQYNMKIVIRGDRNSGKSALWHRLQGKKFLEEYIPTQEIQVTSIHWNYKTTDDVVKVEVWDVVDKGQKLPLPEGVGKGKRRGENLKLENEPQESETEMALDAEFLDVYKNCNGVIMMFDITKQWTFNYILRELPKVPTHIPVCVLGNQRDMGEHRVILPDDIRDFINSLNRPPGSSYIHYAESSMKNGFGLKYLHRFFNIPFLQLQRETLLRQLETNQLDIDATLEELSVQQETEDQNYDIFLEMMEARKAYGSPAPSNGQSPSSGSQSPVVLPGAASPSNSSPSTPQAPVPLQTPAPPPPPSIPHPTAQTTATQVHQTLSQTLEASPATPTPAPAQLAAPAAQKRGFISRLFGSSAAETSPDKPESTGSESVKASGKVQSVDEFVPEVGLDRTFLDDGGAAAAAAAKSKNKPPASAPILDSDSDGEGRGNPLVSGFQDDLDPDDRVPSQPAVKAVVPSKDITLTSDEEAEDSPVHQQKAISSSGPNTKGSSLNSVKQLQTKSKAAERPQSLKTTAGSAVQRASLKTGGTVEADSDSDREAPVAQQMLSFVMDDPDFESEEIDIPKVKKGAFSARDDFSDRSDDGFVLAGLPELPKPVAPSFQTLNSDIDLFGLGFEEATPKTKESSEDQEDNDSRHSTKDKKKKKKKSKEEDEKSSKKRHKHKKKEKEEPGTGDEKDKKKKKKSSRTKKAANVDDLEAFLAGGDGPGNSEGGDYEEL", "length": 757 }, "evidence": [ { "id": "HGNC:24703", "url": "https://alliancegenome.org/gene/HGNC:24703#orthology", "database": "AGR" }, { "id": "MGI:2442633", "url": "https://alliancegenome.org/gene/MGI:2442633#orthology", "database": "AGR" }, { "id": "RGD:1307615", "url": "https://alliancegenome.org/gene/RGD:1307615#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZKQ4-1", "protein_name": "Rab-like protein 6", "gene_name": "Rabl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSALKKLVGSEQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALWHRLQGKKFVEEYIPTQEIQVTSIHWNYKTTDDVVKVEVWDVVDKGKCKKRGDCLKTENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYVLRELPKVPTHVPVCVLGNYRDMGEHRVILPDDVRDFIEHLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLLRQLETNQLDIDATLEELSVQQETEDQNYSIFLEMMEARSRGHASPLAANGQSPSSGSQSPVVPPSAVSTGSSSPSTPQPAPQLSLGVSSTCPSAPSPAPSLEATPSSVHPPAPAPAQRRSIISRLFGTSPAAEATISPPEPAPALEAPVRVQNVEDFVPEDGLDRSFLEDTTVPKDKKVGAKGPQQDSDSDDGEALGGNPMVAGFQDDVDIEDQPHGQSLLPSDPIPSKNISLSSEEEAEGLAGHPRVSPQQCSEPETKWSSTKASHPQKKGAPTRGITPWSDGLTTDGSQRPQEGKDKQVSSESDPEGPIAAQMLSFVMDDPDFESDESDTQKRVGRFPVREDLSDVTDEDTGPAQPPPPSKFPVPAFRLKNDSDLFGLGLEELGPKESSEEDKDSKLPSKEKKKKKKKSKEEEEKATKKKSKHKKSKDKEEGKEDGKKRRKPPRSKEQKAADELEAFLGGGAPGSRHPAGGDYEEL", "length": 718 }, "evidence": [ { "id": "HGNC:24703", "url": "https://alliancegenome.org/gene/HGNC:24703#orthology", "database": "AGR" }, { "id": "MGI:2442633", "url": "https://alliancegenome.org/gene/MGI:2442633#orthology", "database": "AGR" }, { "id": "RGD:1307615", "url": "https://alliancegenome.org/gene/RGD:1307615#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-97", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-97#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3YEC7-1", "protein_name": "Rab-like protein 6", "gene_name": "RABL6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSALKKLVGSDQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALWHRLQGRPFVEEYIPTQEIQVTSIHWSYKTTDDIVKVEVWDVVDKGKCKKRGDGLKMENDPQEAESEMALDAEFLDVYKNCNGVVMMFDITKQWTFNYILRELPKVPTHVPVCVLGNYRDMGEHRVILPDDVRDFIDNLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLLRQLETNQLDMDATLEELSVQQETEDQNYGIFLEMMEARSRGHASPLAANGQSPSPGSQSPVVPAGAVSTGSSSPGTPQPAPQLPLNAAPPSSVPPVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDVDLEDQPRGSPPLPAGPVPSQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRRGTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDPSDVTDEDEGPAEPPPPPKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQQRPPRSRERTAADELEAFLGGGAPGGRHPGGGDYEEL", "length": 729 }, "evidence": [ { "id": "HGNC:24703", "url": "https://alliancegenome.org/gene/HGNC:24703#orthology", "database": "AGR" }, { "id": "MGI:2442633", "url": "https://alliancegenome.org/gene/MGI:2442633#orthology", "database": "AGR" }, { "id": "RGD:1307615", "url": "https://alliancegenome.org/gene/RGD:1307615#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-97", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-97#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5U3K5-1", "protein_name": "Rab-like protein 6", "gene_name": "Rabl6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSALKKLVGSEQAPGRDKNIPAGLQSMNQALQRRFAKGVQYNMKIVIRGDRNTGKTALWHRLQGKKFVEEYIPTQEIQVTSIHWNYKTTDDVVKVEVWDVVDKGKCKKRGDGLKTENDPQEAESELALDAEFLDVYKNCNGVVMMFDITKQWTFNYVLRELPKVPTHVPVCVLGNYRDMGEHRVILPDDVRDFIEHLDRPPGSSYFRYAESSMKNSFGLKYLHKFFNIPFLQLQRETLLRQLETNQLDIDATLEELSVQQETEDQNYSIFLEMMEARSRGHASPLAANGQSPSSGSQSPVVPPSAVSTGSSSPSTPQPAPQLSLGVSSTCPSAPSPVPSLEAMPSSVHSSAPAPTPAPAPAPAQRRSIISRLFGTSPAAEVTPSPPEPAPALEAPARVQNVEDFVPEDGLDRSFLEDTSVPKDKKVGAKGPQQDSDSDDGEALGGNPMVAGFQDDVDIEDQTHGKSLLPSDPMPSKNISLSSEEEAEGLAGHPRVAPQQCSEPETKWSSTKVSHPQKKRAPTRGTPPWSDGLTTDDSERPQEGKDKQVSSESDPEGPIAAQMLSFVMDDPDFESDESDTQRRMGRFPVREDLSDVTDEDTGPAQPPPPSKLPGAFRLKNDSDLFGLGLEEMGPKESSDEDRDSKLPSKEKKKKKKKSKEEEEKTTKKKSKHKKSKDKEEGKEDRKKKRKPPRSKEQKAADELEAFLGGGAPGSRHPGGGDYEEL", "length": 725 }, "evidence": [ { "id": "HGNC:24703", "url": "https://alliancegenome.org/gene/HGNC:24703#orthology", "database": "AGR" }, { "id": "MGI:2442633", "url": "https://alliancegenome.org/gene/MGI:2442633#orthology", "database": "AGR" }, { "id": "RGD:1307615", "url": "https://alliancegenome.org/gene/RGD:1307615#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-97", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-97#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL07", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL07" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL07", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL07" } ], "pmid": "" }, { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL07", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL07" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 287, "end_pos": 289, "annotation": "n_glycosylation_sequon" }, { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 287, "end_pos": 289 }, { "start_pos": 30, "end_pos": 32 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PL10-1", "uniprot_ac": "A0A8M9PL10", "uniprot_id": "A0A8M9PL10_DANRE", "mass": { "chemical_mass": 76617.0, "monoisotopic_mass": 76617.0 }, "refseq": { "ac": "XP_021325589", "name": "zinc finger and BTB domain-containing protein 46 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325589" }, "gene_names": [ { "name": "zbtb46", "type": "recommended", "evidence": [ { "id": "A0A8M9PL10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL10" } ] }, { "name": "zbtb46", "type": "synonym", "evidence": [ { "id": "XP_021325589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325589" } ] } ], "protein_names": [ { "name": "Zinc finger and BTB domain-containing protein 46 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PL10", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL10/entry#names_and_taxonomy" } ] }, { "name": "zinc finger and BTB domain-containing protein 46 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325589", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325589" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325589" } ] }, { "annotation": "Transcription regulator that mediates differentiation of conventional and non-conventional dendritic cells, and which is involved in tolerance to gut microbiota. Together with RORgammaT (RORC), specifically expressed in type 3 innate lymphoid cells (ILC3s) that are required for tolerance to gut microbiota, to mediate differentiation of peripherally-induced regulatory T-cells (pTreg), which suppress inflammatory responses to commensal microorganisms. Functions as a transcription corepressor for PRDM1.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PWR8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PWR8#function" }, { "database": "UniProtKB", "id": "ARBA00094402", "url": "https://www.uniprot.org/uniprotkb/ARBA00094402#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL10", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL10" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zbtb46", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL10", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-352", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-352", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PL10", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PL10", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18230", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18230", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "570537", "url": "https://www.ncbi.nlm.nih.gov/gene/570537", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570537", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570537", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PL10", "url": "https://www.orthodb.org/?gene=A0A8M9PL10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46105:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46105:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325589", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325589", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PL10", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PL10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PWR8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PWR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PWR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PWR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IN19", "url": "https://www.uniprot.org/uniprotkb/A0AC58IN19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IN19-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IN19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-352", "url": "https://zfin.org/ZDB-GENE-090313-352", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNNRKEDMEITSHYRQLLRELNEQRQHGILCDVCVIVEGKIFKAHKNVLLGSSRYFKTLYCQVKKGSEQQATITHLDIVTAQGFKTILDFMYSAHLALTSKNVIEVMSAASYLQMTDIVQACHGFIKAALDISIRSELADELADIEMGNVVSSIGGGAVPGVGGASEALASMISARSSSPWLARRTSPANSSGDSAIASCHEGSSNYGKEDQEPKSHESQEDACLQPLWPADYRSVQVKEEQVSPSNLQDGAGRGVQGTPGDQGGRGEGGWQPPGSGRRKNRKNKDTVRHITQQNEGDSRTASPLPSMLSTPGWNYSNQDIPGAEVTEPNISDSRSERMDLLVKQEEATAGDSGFLSGERDEAVAQERAGSVANLRAALMSKNSLLSLGAEMLGEENPLLFDYLPKGGHSLSRPRCSNGSSSSHHPGGLFGSKHGASSSSPPSTLPPLPLLLPPPPSMLQPPGAHYMPQSGGPPDKLYAEQAPKASPTEEEMQEEDNSPNNNAELERIQVPVEEDQMVEEKHGVCVAEVQGGGPGWRQELACSLCKQLFSSLLQLRQHEYSHTLSLMALSLDCLDHHRPLVASASPLNPQPARYHCSQCPASFTLKSNADRHEKTIHLKRKLMQCVYCLKHFRDRTDLNRHLSSVHSSERVYTCPACSRTFSTQKNLATHGKVCCQSGISPTEQLWNLHGLKEDHHGHIHVDD", "length": 703, "header": "tr|A0A8M9PL10-1|A0A8M9PL10_DANRE Isoform 1 of Zinc finger and BTB domain-containing protein 46 isoform X1 OS=Danio rerio OX=7955 GN=zbtb46 PE=4 SV=1 CANONICAL=A0A8M9PL10-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PL10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL10/entry#A0A8M9PL10-1", "sequence": { "sequence": "MNNRKEDMEITSHYRQLLRELNEQRQHGILCDVCVIVEGKIFKAHKNVLLGSSRYFKTLYCQVKKGSEQQATITHLDIVTAQGFKTILDFMYSAHLALTSKNVIEVMSAASYLQMTDIVQACHGFIKAALDISIRSELADELADIEMGNVVSSIGGGAVPGVGGASEALASMISARSSSPWLARRTSPANSSGDSAIASCHEGSSNYGKEDQEPKSHESQEDACLQPLWPADYRSVQVKEEQVSPSNLQDGAGRGVQGTPGDQGGRGEGGWQPPGSGRRKNRKNKDTVRHITQQNEGDSRTASPLPSMLSTPGWNYSNQDIPGAEVTEPNISDSRSERMDLLVKQEEATAGDSGFLSGERDEAVAQERAGSVANLRAALMSKNSLLSLGAEMLGEENPLLFDYLPKGGHSLSRPRCSNGSSSSHHPGGLFGSKHGASSSSPPSTLPPLPLLLPPPPSMLQPPGAHYMPQSGGPPDKLYAEQAPKASPTEEEMQEEDNSPNNNAELERIQVPVEEDQMVEEKHGVCVAEVQGGGPGWRQELACSLCKQLFSSLLQLRQHEYSHTLSLMALSLDCLDHHRPLVASASPLNPQPARYHCSQCPASFTLKSNADRHEKTIHLKRKLMQCVYCLKHFRDRTDLNRHLSSVHSSERVYTCPACSRTFSTQKNLATHGKVCCQSGISPTEQLWNLHGLKEDHHGHIHVDD", "length": 703, "header": "tr|A0A8M9PL10-1|A0A8M9PL10_DANRE Isoform 1 of Zinc finger and BTB domain-containing protein 46 isoform X1 OS=Danio rerio OX=7955 GN=zbtb46 PE=4 SV=1 CANONICAL=A0A8M9PL10-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PWR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL10/entry#A0A8M9PWR8-1", "sequence": { "sequence": "MNNRKEDMEITSHYRQLLRELNEQRQHGILCDVCVIVEGKIFKAHKNVLLGSSRYFKTLYCQVKKGSEQQATITHLDIVTAQGFKTILDFMYSAHLALTSKNVIEVMSAASYLQMTDIVQACHGFIKAALDISIRSELADELADIEMGNVVSSIGGGAVPGVGGASEALASMISARSSSPWLARRTSPANSSGDSAIASCHEGSSNYGKEDQEPKSHESQEDACLQPLWPADYRSVQVKEEQVSPSNLQDGAGRGVQGTPGDQGGRGEGGWQPPGSGRRKNRKNKDTVRHITQQNEGDSRTASPLPSMLSTPGWNYSNQDIPGAEVTEPNISDSRSERMDLLVKQEEATAGDSGFLSGERDEAVAQERAGSVANLRAALMSKNSLLSLGAEMLGEENPLLFDYLPKGGHSLSLNDFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIKHGSRRHGVCADCSGRGMAALLDQNGEDGSPEEELLYPGDHRFPDDTADGDGEEEMMVEAEIMGEGEEENGKWRAGSGMSQRDDRAIDDGKEESDSALEGDTRAGSEKDFSWIS", "length": 610, "header": "tr|A0A8M9PWR8-1|A0A8M9PL10_DANRE Computationally mapped isoform of Zinc finger and BTB domain-containing protein 46 isoform X1 OS=Danio rerio OX=7955 GN=zbtb46 PE=4 SV=1 CANONICAL=A0A8M9PL10-1" }, "locus": {} }, { "isoform_ac": "A0AC58IN19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL10/entry#A0AC58IN19-1", "sequence": { "sequence": "MNNRKEDMEITSHYRQLLRELNEQRQHGILCDVCVIVEGKIFKAHKNVLLGSSRYFKTLYCQVKKGSEQQATITHLDIVTAQGFKTILDFMYSAHLALTSKNVIEVMSAASYLQMTDIVQACHGFIKAALDISIRSELADELADIEMGNVVSSIGGGAVPGVGGASEALASMISARSSSPWLARRTSPANSSGDSAIASCHEGSSNYGKEDQEPKSHESQEDACLQPLWPADYRSVQVKEEQVSPSNLQDGAGRGVQGTPGDQGGRGEGGWQPPGSGRRKNRKNKDTVRHITQQNEGDSRTASPLPSMLSTPGWNYSNQDIPEQQDPWDFISHSPSESSVEAEKSRRGSQARDARKKGGRK", "length": 361, "header": "tr|A0AC58IN19-1|A0AC58IN19_DANRE Computationally mapped isoform of Zinc finger and BTB domain-containing protein 46 isoform X3 OS=Danio rerio OX=7955 GN=zbtb46 PE=4 SV=1 CANONICAL=A0A8M9PL10-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 259, "start_aa": "Thr", "end_pos": 259, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr259", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:570537", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570537", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZTY1-1", "protein_name": "Zinc finger and BTB domain-containing protein 46", "gene_name": "Zbtb46", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSDQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALDISIKSDASDELSEFEIGTPASNSTEALISAVMAGRSISPWLARRTSPANSSGDSAIASCHEGGSSYGKEDQEPKADGPDDVSSQSLWPGDVGYGSLRIKEEQISPSHYGGSELSSSKDAAIQNSLSEQGSGDGWQPTGRRKNRKNKETVRHITQQVEEDSQAGSPVPSFLPTSGWPFSSRDSNVDLTVTEASSLDSRGERAELYAHHIDEGLLGGETSYLGPPLTPEKEEALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPKGAHSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIKHGSRRHGVCADCAGRGVGTPLDHGGGGEGSPEALFAGEGPYLEDPDDPRGEVEEELGEDEDEDVAKWKDDVGLAHEDALLGDDKDDEDSPQGPHSPAGEPDKDFAWIS", "length": 601 }, "evidence": [ { "id": "HGNC:16094", "url": "https://alliancegenome.org/gene/HGNC:16094#orthology", "database": "AGR" }, { "id": "MGI:1919397", "url": "https://alliancegenome.org/gene/MGI:1919397#orthology", "database": "AGR" }, { "id": "RGD:1307408", "url": "https://alliancegenome.org/gene/RGD:1307408#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-352", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-352#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O77459-1", "protein_name": "Transcription factor Ken", "gene_name": "ken", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKEFQRMLMLQYSKHGECILKEIGAAFRGEHPADLTIVCENKVKLHAHKLVLAAASPLIRNLLEDTHLSDCSTTVYFPDVNATYFKFLLDFLYSGQTCITSRDVNYLHDLLLLLQIKSDSWKTTDSAYLSSKCGGLRDRADRRKQQYTSPQNLEPDQTLKYEVDSVDESRNAADFSSAFNSNDNCESAAECERSGGHNNKEEDEDDCTHKDNKSDKDTDEIVNLSNAPPSGTSGSNSNISTSSNHQQQQHHHHHHHNHNNNNNNNNNNSSSSTINPVNLSLDLRTKSENSASRTLGSGSDHSGIDLAVTASESTKRKGLFFDSHKDVMKPLSDGSDINSSPENYVVTPHRKRRPGFHNTQSDNQPFTSYPHSLLEELRLAKSTTSPISGFGSEKNMLAHLEDGALNGDTLTPDRKHLLEAQRNRAQSPEIPMHLGPQFVYQWQSNQNAAMSAMPNLQSRLSSLSHISLNLDHPEGRSGSASGSGANLAGSNTHASSVREYRCEYCGKQFGMSWNLKTHLRVHTGEKPFACRLCVAMFKQKAHLLKHLCSVHRNVITTTNGADTENRYSCCFCSMCFESVQELVRHLSGHHNNLLLTKNLRE", "length": 601 }, "evidence": [ { "id": "HGNC:16094", "url": "https://alliancegenome.org/gene/HGNC:16094#orthology", "database": "AGR" }, { "id": "MGI:1919397", "url": "https://alliancegenome.org/gene/MGI:1919397#orthology", "database": "AGR" }, { "id": "RGD:1307408", "url": "https://alliancegenome.org/gene/RGD:1307408#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q86UZ6-1", "protein_name": "Zinc finger and BTB domain-containing protein 46", "gene_name": "ZBTB46", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNNRKEDMEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTSEQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIEVMSAASFLQMTDIVQACHDFIKAALDISIKSDASDELAEFEIGASSSSSTEALISAVMAGRSISPWLARRTSPANSSGDSAIASCHDGGSSYGKEDQEPKADGPDDVSSQPLWPGDVGYGPLRIKEEQVSPSQYGGSELPSAKDGAVQNSFSEQSAGDAWQPTGRRKNRKNKETVRHITQQVEDDSRASSPVPSFLPTSGWPFSSRDSNADLSVTEASSSDSRGERAELYAQVEEGLLGGEASYLGPPLTPEKDDALHQATAVANLRAALMSKNSLLSLKADVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERPYPCEICGKKFTRREHMKRHTLVHSKDKKYVCKVCSRVFMSAASVGIRHGSRRHGVCTDCAGRGMAGPLDHGGGGGEGSPEALFPGDGPYLEDPEDPRGEAEELGEDDEGLAPEDALLADDKDEEDSPRPRSPPGGPDKDFAWLS", "length": 589 }, "evidence": [ { "id": "HGNC:16094", "url": "https://alliancegenome.org/gene/HGNC:16094#orthology", "database": "AGR" }, { "id": "MGI:1919397", "url": "https://alliancegenome.org/gene/MGI:1919397#orthology", "database": "AGR" }, { "id": "RGD:1307408", "url": "https://alliancegenome.org/gene/RGD:1307408#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-352", "url": 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Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068071000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071000" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL47", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL47" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC137488273", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL47", "locus": {} } ], "crossref": [ { "id": "dre:137488273", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:137488273", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_068071000", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068071000", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PL47", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PL47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAKTIARTARSIAAQINECCSYIHSKYQQLQAFRRQVKRRTRPKHWDWIEDFELEHELRFPTRGPRSLLKLRNLQHFLRETEQNWWDFRPPRVPGRPHRVLRINLRDRPIKALLSTELFPPKPVDRTERHYCRKLLLMERPLEISLPADILEEIRALEHLEEEQGLPPHLHCSSGQEDYYSADEE", "length": 185, "header": "tr|A0A8M9PL47-1|A0A8M9PL47_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC137488273 PE=4 SV=1 CANONICAL=A0A8M9PL47-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PL47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL47/entry#A0A8M9PL47-1", "sequence": { "sequence": "MAKTIARTARSIAAQINECCSYIHSKYQQLQAFRRQVKRRTRPKHWDWIEDFELEHELRFPTRGPRSLLKLRNLQHFLRETEQNWWDFRPPRVPGRPHRVLRINLRDRPIKALLSTELFPPKPVDRTERHYCRKLLLMERPLEISLPADILEEIRALEHLEEEQGLPPHLHCSSGQEDYYSADEE", 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PL84-1", "uniprot_ac": "A0A8M9PL84", "uniprot_id": "A0A8M9PL84_DANRE", "mass": { "chemical_mass": 43295.0, "monoisotopic_mass": 43295.0 }, "refseq": { "ac": "XP_021325664", "name": "voltage-dependent L-type calcium channel subunit beta-4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325664" }, "gene_names": [ { "name": "cacnb3b", "type": "recommended", "evidence": [ { "id": "A0A8M9PL84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84" } ] }, { "name": "cacnb3b", "type": "synonym", "evidence": [ { "id": "XP_021325664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325664" } ] } ], "protein_names": [ { "name": "Voltage-dependent L-type calcium channel subunit beta-3", "type": "recommended", "evidence": [ { "id": "A0A8M9PL84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84/entry#names_and_taxonomy" } ] }, { "name": "Calcium channel voltage-dependent subunit beta 3", "type": "synonym", "evidence": [ { "id": "A0A8M9PL84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84/entry#names_and_taxonomy" } ] }, { "name": "voltage-dependent L-type calcium channel subunit beta-4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021325664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325664" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325664" } ] }, { "annotation": "Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation. Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL84", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84#function" }, { "database": "UniProtKB", "id": "ARBA00045432", "url": "https://www.uniprot.org/uniprotkb/ARBA00045432#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL84", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cacnb3b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090127-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090127-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "559015", "url": "https://www.ncbi.nlm.nih.gov/gene/559015", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008145", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008145", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:559015", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559015", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PL84", "url": "https://www.orthodb.org/?gene=A0A8M9PL84", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11824", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11824", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00625", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00625", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325664", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PL84", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PL84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILQ3", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILW6", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILW6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090127-1", "url": "https://zfin.org/ZDB-GENE-090127-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSASDSSAALLSCKSSADSYTSRPSDSDLSLEEDKEASRREAERQALLQLERAKTKPVAFAVRTNVSYCGALDEDCPVQGAAINFETKDFLHIKEKYNNDWWIGRLVKEGADIAFIPSPVKLEAMRIKQEQKAAQRKMGNASSGGWRSTPPSAAKQKQKQTEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNKKAIMERSNTRSSLAEVQSEIERIFELAKSLQLVVLDADTINHPAQLLKTSLAPIIVYVKVSSPKVLQRLIKSRGKSQSKHLNVQMMAGDKLAQCPPEMFDVILDENQLEDACEHLAEYLDIYWRATHLPGSAPLNPLVEQNVVTPPSANSSQQFSETQELIE", "length": 389, "header": "tr|A0A8M9PL84-1|A0A8M9PL84_DANRE Isoform 1 of Voltage-dependent L-type calcium channel subunit beta-3 OS=Danio rerio OX=7955 GN=cacnb3b PE=3 SV=1 CANONICAL=A0A8M9PL84-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PL84-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84/entry#A0A8M9PL84-1", "sequence": { "sequence": "MSASDSSAALLSCKSSADSYTSRPSDSDLSLEEDKEASRREAERQALLQLERAKTKPVAFAVRTNVSYCGALDEDCPVQGAAINFETKDFLHIKEKYNNDWWIGRLVKEGADIAFIPSPVKLEAMRIKQEQKAAQRKMGNASSGGWRSTPPSAAKQKQKQTEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNKKAIMERSNTRSSLAEVQSEIERIFELAKSLQLVVLDADTINHPAQLLKTSLAPIIVYVKVSSPKVLQRLIKSRGKSQSKHLNVQMMAGDKLAQCPPEMFDVILDENQLEDACEHLAEYLDIYWRATHLPGSAPLNPLVEQNVVTPPSANSSQQFSETQELIE", "length": 389, "header": "tr|A0A8M9PL84-1|A0A8M9PL84_DANRE Isoform 1 of Voltage-dependent L-type calcium channel subunit beta-3 OS=Danio rerio OX=7955 GN=cacnb3b PE=3 SV=1 CANONICAL=A0A8M9PL84-1" }, "locus": {} }, { "isoform_ac": "A0AC58ILQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84/entry#A0AC58ILQ3-1", "sequence": { "sequence": "MRIKQEQKAAQRKMGNASSGGWRSTPPSAAKQKQKQTEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNKKAIMERSNTRSSLAEVQSEIERIFELAKSLQLVVLDADTINHPAQLLKTSLAPIIVYVKVSSPKVLQRLIKSRGKSQSKHLNVQMMAGDKLAQCPPEMFDVILDENQLEDACEHLAEYLDIYWRATHLPGSAPLNPLVEQNVVTPPSANSSQQFSETQELIE", "length": 265, "header": "tr|A0AC58ILQ3-1|A0AC58ILQ3_DANRE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-4 isoform X2 OS=Danio rerio OX=7955 GN=cacnb3b PE=3 SV=1 CANONICAL=A0A8M9PL84-1" }, "locus": {} }, { "isoform_ac": "A0AC58ILW6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84/entry#A0AC58ILW6-1", "sequence": { "sequence": "MRHLGAGDPLLPLQTEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNKKAIMERSNTRSSLAEVQSEIERIFELAKSLQLVVLDADTINHPAQLLKTSLAPIIVYVKVSSPKVLQRLIKSRGKSQSKHLNVQMMAGDKLAQCPPEMFDVILDENQLEDACEHLAEYLDIYWRATHLPGSAPLNPLVEQNVVTPPSANSSQQFSETQELIE", "length": 243, "header": "tr|A0AC58ILW6-1|A0AC58ILW6_DANRE Computationally mapped isoform of Voltage-dependent L-type calcium channel subunit beta-4 isoform X3 OS=Danio rerio OX=7955 GN=cacnb3b PE=3 SV=1 CANONICAL=A0A8M9PL84-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:559015", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559015", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B8T1-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-3", "gene_name": "cacnb3a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVQVKMSKSSADPLSGVESASQSHYFQLPRKLPKRKGRFKRSDGSTSSDTTSSFIKRQGSADSYTSRPSDSDLSAEEDREAYRREAERQAQLQLERAKSKPVAFAVKTNVNYCGALDEECPVQGAAINFEAKDFLHIKEKYNNDWWIGRLVKEGADISFIPSPLRLEAMRIKQEQKQQRKSGNSSSSLGDMVSGGWRSTPPSAGETKQKLKQTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNKRPIMERSNTRTSLAEVQSEIERIFELAKTLQLVILDADTINHPAQLAKTSLAPIIVYVKVTSPKVLQRLIKSRGKSQSKHLNVQMMAADKLTQCPPEMFDVILDENQLEDACEHLAEYLEVYWRATHLPGTTPLNPLLEQNLMTPPSAISSLQNQQLSPAGGGVGVEEEEQGEQDSLMPSDEASDSRSLHRGGSSSLHPPEDEEEEEEEEDDDYQPHRHSNPYRDVYPPNRNHPGGIHSANGHESQDRLLQQRDSQDGHNQRNNRQRSRAWPRDNY", "length": 555 }, "evidence": [ { "id": "HGNC:1403", "url": "https://alliancegenome.org/gene/HGNC:1403#orthology", "database": "AGR" }, { "id": "MGI:103307", "url": "https://alliancegenome.org/gene/MGI:103307#orthology", "database": "AGR" }, { "id": "RGD:2248", "url": "https://alliancegenome.org/gene/RGD:2248#orthology", "database": "AGR" }, { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BBA6-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-1", "gene_name": "cacnb1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVQEGNMSRTPSTSTQEIQMDMFDHHGSHAQGKYAKRKSRFKRSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDPEALRKEADRQALATLEKAKTKPVAFAVRTNVGYNPGPNDDVPVQGMAISFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLESTRQLQEQRMRQNRLSSSKSGGSSSLDVATGARRPTPPGTADLSSGLYDDALDSDVEEAETADTRDHKGVGGSVTSPQGNLPRLPFFKKMEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHKFEGRISITRVTADISLAKRSVLNNPSKHTIIERSSTRSSLAEVQSEIERIFELARTLQLVALDADTINHPSQLAKTSLAPIIVYIKIASPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDIILDENQLEDACEHLAEYLEAYWKATHPPSSNPPNPLLNRTMATAALAASPEPVSNLQGPFLVHGEQKREMPERGGLQDYQSDLSGKQPLRSSRSQLQTGSRGLSRQDTFDSETQGSRDSAYTDDMETDPYEEPDPCRSYRLNPAHHAPRQASWEDEGAEPDQENLNMVPPPANQHQRGRGKLRERYCQDAEAGGATTGRNHNQEEWSRDVYIR", "length": 642 }, "evidence": [ { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13ABH3-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-2b isoform 1", "gene_name": "cacnb2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFCCGLGHWRREQSTYGSADRQDTGATEEKEKNAQVQLDKAKYKPVAFAVRTNFTYTPADDDNVPIPGHGVSFEAKDFLHIKEKFNNDWWIGRPVKEGGEVGFIPSPVNLETILIRREVQARKAAKALANKAASAAKDDLNAKKAAPPQTVQQVKKKSGEQLAAYDVVPSMRPVVLMGPSLKGYEVTDMMQKALFDYLKHRFEGRITITRVTADIALAKRSILNNPSKHAIMDRSNTRTNLAQIQGEVERIFELARSLQLVVLDADTINHPLQLSKTSLAPILVYVKISSPKVLTRLIKTRGKSQTKHLNVQMVAADKLAQCPNEMFDVILDENQLSDACEHIADYLEAYWRATHPPEMEPPNPMLEKLAENTLPTSPTPAKDEQKSKKTAATKRKGSLEHQQEHQPQAQETREEEDEEEEEEVQEEAEEEERLLRSEPKRHSHHHHHHHHHHNRSGTSRPPETQNKHQQHMRQPQPADMELLPARNTSYASEPRSRRMIPGEGDPDQTEVYQNRTTTQRDHNHQHHNHHHRHHHHRRGTTDAQPEYSHHGQQDYELEHNEHNRQQRPQSHLRSHHYTHPHHNHYHYQRDRERDRGVETEEWTEDMYIHR", "length": 610 }, "evidence": [ { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TUG0-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-2", "gene_name": "cacnb2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKASWIRLLKRATGNRVKNNIGGSADSYTSRPSDSDVSLEEDKETLRREAERQAQAQLDKAKSKPVAFAVRTNVGYSASSEDDVPVPGTGISFDPKDFLHVKEKFNNDWWIGRLVKEGCDIGFIPSPVKLESSRLRQEQRAKQGRFYSSKSGANSSSSLGDIVSNSRKSTPPSSAVDIDAAGLDAEESDPPPHQRSPKASPNTVISPLAREKRMPFFKKTEHAPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRITITRVAADISLAKRSVLNNPSKHAIIERSNTRSNLAEVQSEIERIFELARTLQLVVLDADTINHPSQLGKTCLAPIIVYIKITSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPSELFDIILDENQLEDACEHMADYLELYWKSTHPPSGAPSTPLLDKLSAVTAAAVACKEQLTNTQPKGTGSDEHADRAAANRTSFYEDYHHHHHPQQQHYQTQKQESFEEEEEEEDDDEENTDQRHDNRDQQNHHKNQHSSSTRTERHHHHRHHHHHHHHRHHHSRTARTLSKQETLESTETQTHSQPQQEEEQESVQPNHHRHHHHHHRHHHRNEKEKEYDHNERNSRQRGKQKSQREHHHHHERRKHYIEQ", "length": 636 }, "evidence": [ { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A055-2", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-4", "gene_name": "Cacnb4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSSYAKNGAADGPHSPSSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTTTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTSSSTPMTPLLGRNVGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGCSHDSRHRL", "length": 519 }, "evidence": [ { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M9PD84-1", "protein_name": "Ca2+-channel-protein-beta-subunit, isoform L", "gene_name": "Ca-beta", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVQRASSSDAPSVQGGQHRESRFGLGYPSYQSGYNKLFTQGSADSNYSQPSSDLSLDEEKESLRREKERQALSQLDKARSKPVAFAVRTNVAYDGAIDDDSPVQGGAVSFEIREFLHIKEKYDNNWWIGRLVKEGCDVGFIPSPAKLDNIRMQNQTRPSRLYGTKGSSSGNLGAGGQAGAEPSRGSTPPTPGDESDSMGPGRHGKTPAAAANKEKRKPFFKKQETASPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRIIITRVMADISLAKRSIMNNPSKRAIMERSSSRSDCLGKVQEEIERIFELARSLQLVVLDCDTINHPSQLAKTSLAPTIVYLKISSSKVLQRLIKSRGKSQAKNLSVQMVAAEKLAQCPPDMFDVILDENQLEDACEHIAEYLETYWKATHPDIRAVPPIARPLPQEASPSADPARLGPTPPVDGEEFVDEQDPRMGMSGGDREGSRERDRDSRERERERERERDYWDREFNRDRSSKDRERDLEWERERAREWERERERDWDREFDWDQGGTSYQHSRRQPTSVRHQERGGGVGAGGGGGGVGGGYERDRERERYERRERDLMHYDLNSDELLDERNFEYPAMRSGPSGASHHGHLSRGGRLLEDPDFEREEAQMRMSSSRYGPSTRIDDPRDLPRGATVVDRDEYSPHRGGGSSRRMLNAMSRPLGLPRQSSLPSNRAPVSYLPRQSSLGTHWLSSSSQSNLDQGPQSRRELYPLLHQPQSYSQPRSQYTSHSYTSAPQHTSQSRSQSQSHSQSHSQYRYSVQDTSFAHPPRSLREEFLSPTMSKVEAVTHAIRNKIIVEEDEEDILSTDRFY", "length": 844 }, "evidence": [ { "id": "HGNC:1403", "url": "https://alliancegenome.org/gene/HGNC:1403#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090127-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090127-1#orthology", "database": "AGR" }, { "id": "MGI:103307", "url": "https://alliancegenome.org/gene/MGI:103307#orthology", "database": "AGR" }, { "id": "RGD:2248", "url": "https://alliancegenome.org/gene/RGD:2248#orthology", "database": "AGR" }, { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "O00305-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-4", "gene_name": "CACNB4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSSSYAKNGTADGPHSPTSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTSTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTTSSTPMTPLLGRNLGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGYSHDSRHRL", "length": 520 }, "evidence": [ { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54283-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-1", "gene_name": "Cacnb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQKSGMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQTLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSRTPPNPLLNRTMATAALAVSPAPVSNLQGPYLVSGDQPLDRATGEHASVHEYPGELGQPPGLYPSNHPPGRAGTLWALSRQDTFDADTPGSRNSVYTEPGDSCVDMETDPSEGPGPGDPAGGGTPPARQGSWEEEEDYEEEMTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGQGVYIR", "length": 597 }, "evidence": [ { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P54284-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-3", "gene_name": "CACNB3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKARRSGNPSSLSDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPAPGPGLLGPPSAIPGLQNQQLLGERGEEHSPLERDSLMPSDEASESSRQAWTGSSQRSSRHLEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRLLAQDSEHNHSDRNWQRNRPWPKDSY", "length": 484 }, "evidence": [ { "id": "HGNC:1403", "url": "https://alliancegenome.org/gene/HGNC:1403#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090127-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090127-1#orthology", "database": "AGR" }, { "id": "MGI:103307", "url": "https://alliancegenome.org/gene/MGI:103307#orthology", "database": "AGR" }, { "id": "RGD:2248", "url": "https://alliancegenome.org/gene/RGD:2248#orthology", "database": "AGR" }, { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54285-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-3", "gene_name": "Cacnb3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKARRSGNPSSLGDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLEDACEHLAEYLEVYWRATHHPAPGPGLLGPPSAIPGLQNQQLLGERVEEHSPLERDSLMPSDEASESSRQAWTGSSQRSSRHLEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRLLAQDSEHDHNDRNWQRNRPWPKDSY", "length": 484 }, "evidence": [ { "id": "HGNC:1403", "url": "https://alliancegenome.org/gene/HGNC:1403#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090127-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090127-1#orthology", "database": "AGR" }, { "id": "MGI:103307", "url": "https://alliancegenome.org/gene/MGI:103307#orthology", "database": "AGR" }, { "id": "RGD:2248", "url": "https://alliancegenome.org/gene/RGD:2248#orthology", "database": "AGR" }, { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P54287-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-3", "gene_name": "Cacnb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYDDSYVPGFEDSEAGSADSYTSRPSLDSDVSLEEDRESARREVESQAQQQLERAKHKPVAFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVKEGGDIAFIPSPQRLESIRLKQEQKARRSGNPSSLSDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLNNPGKRTIIERSSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAKTSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQLDDACEHLAEYLEVYWRATHHPAPGPGMLGPPSAIPGLQNQQLLGERGEEHSPLERDSLMPSDEASESSRQAWTGSSQRSSRHLEEDYADAYQDLYQPHRQHTSGLPSANGHDPQDRLLAQDSEHDHNDRNWQRNRPWPKDSY", "length": 484 }, "evidence": [ { "id": "HGNC:1403", "url": "https://alliancegenome.org/gene/HGNC:1403#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090127-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090127-1#orthology", "database": "AGR" }, { "id": "MGI:103307", "url": "https://alliancegenome.org/gene/MGI:103307#orthology", "database": "AGR" }, { "id": "RGD:2248", "url": "https://alliancegenome.org/gene/RGD:2248#orthology", "database": "AGR" }, { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q02641-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-1", "gene_name": "CACNB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVQKTSMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQKLRQNRLGSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLERATGEHASMHEYPGELGQPPGLYPSSHPPGRAGTLRALSRQDTFDADTPGSRNSAYTELGDSCVDMETDPSEGPGLGDPAGGGTPPARQGSWEDEEEDYEEELTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGRGVYIR", "length": 598 }, "evidence": [ { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q08289-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-2", "gene_name": "CACNB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVQRDMSKSPPTAAAAVAQEIQMELLENVAPAGALGAAAQSYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLEAYWKATHPPSSSLPNPLLSRTLATSSLPLSPTLASNSQGSQGDQRTDRSAPIRSASQAEEEPSVEPVKKSQHRSSSSAPHHNHRSGTSRGLSRQETFDSETQESRDSAYVEPKEDYSHDHVDHYASHRDHNHRDETHGSSDHRHRESRHRSRDVDREQDHNECNKQRSRHKSKDRYCEKDGEVISKKRNEAGEWNRDVYIRQ", "length": 660 }, "evidence": [ { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CC27-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-2", "gene_name": "Cacnb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQSDTSKSPPVAAVAQESQMELLESAAPAGALGAQSYGKGARRKNRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQESFDVILDENQLEDACEHLADYLEAYWKATHPPSGNLPNPLLSRTLASSTLPLSPTLASNSQGSQGDQRPDRSAPRSASQAEEEPCLEPVKKSQHRSSSATHQNHRSGTGRGLSRQETFDSETQESRDSAYVEPKEDYSHEHVDRYVPHREHNHREETHSSNGHRHRESRHRSRDMGRDQDHNECIKQRSRHKSKDRYCDKEGEVISKRRNEAGEWNRDVYIRQ", "length": 655 }, "evidence": [ { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R0S4-3", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-4", "gene_name": "Cacnb4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSSYGKNGAADGPHSPSSQVARGTTTRRSRLKRSDGSTTSTSFILRQGSADSYTSRPSDSDVSLEEDREAIRQEREQQAAIQLERAKSKPVAFAVKTNVSYCGALDEDVPVPSTAISFDAKDFLHIKEKYNNDWWIGRLVKEGCEIGFIPSPLRLENIRIQQEQKRGRFHGGKSSGNSSSSLGEMVSGTFRATPTTTAKQKQKVTEHIPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKRAIIERSNTRSSLAEVQSEIERIFELARSLQLVVLDADTINHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMFDVILDENQLEDACEHLGEYLEAYWRATHTSSSTPMTPLLGRNVGSTALSPYPTAISGLQSQRMRHSNHSTENSPIERRSLMTSDENYHNERARKSRNRLSSSSQHSRDHYPLVEEDYPDSYQDTYKPHRNRGSPGGCSHDSRHRL", "length": 519 }, "evidence": [ { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R3Z5-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-1", "gene_name": "Cacnb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQKSGMSRGPYPPSQEIPMEVFDPSPQGKYSKRKGRFKRSDGSTSSDTTSNSFVRQGSAESYTSRPSDSDVSLEEDREALRKEAERQALAQLEKAKTKPVAFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCEVGFIPSPVKLDSLRLLQEQTLRQNRLSSSKSGDNSSSSLGDVVTGTRRPTPPASAKQKQKSTEHVPPYDVVPSMRPIILVGPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADISLAKRSVLNNPSKHIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLEAYWKATHPPSSTPPNPLLNRTMATAALAASPAPVSNLQGPYLASGDQPLDRATGEHASVHEYPGELGQPPGLYPSNHPLGRAGTLRALSRQDTFDADTPGSRNSAYTEPGDSCVDMETDPSEGPGPGDPAGGGTPPARQGSWEDEEDYEEEMTDNRNRGRNKARYCAEGGGPVLGRNKNELEGWGQGVYTR", "length": 597 }, "evidence": [ { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VGC3-1", "protein_name": "Voltage-dependent L-type calcium channel subunit beta-2", "gene_name": "Cacnb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQSDTSKSPPIAAVAQESQMELLESAAPAGALGAQSYGKGARRKNRFKGSDDSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRREAERQAQAQLEKAKTKPVAFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCEIGFIPSPVKLENMRLQHEQRAKQGKFYSSKSGGNSSSSLGDIVPSSRKSTPPSSAIDIDATGLDAEENDIPANHRSPKPSANSVTSPHSKEKRMPFFKKTEHTPPYDVVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPQESFDVILDENQLEDACEHLADYLEAYWKATHPPSSNLPNPLLSRTLATSTLPLSPTLASNSQGSQGDQRTDRSAPRSASQAEEEPCLEPVKKSQHRSSSATHQNHRSGTGRGLSRQETFDSETQESRDSAYVEPKEDYSHEHVDRYVPHREHNHREESHSSNGHRHREPRHRTRDMGRDQDHNECSKQRSRHKSKDRYCDKEGEVISKRRSEAGEWNRDVYIRQ", "length": 655 }, "evidence": [ { "id": "FB:FBgn0287724", "url": "https://alliancegenome.org/gene/FB:FBgn0287724#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL84", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL84", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84" } ], "pmid": "" }, { "name": "voltage-gated calcium channel complex", "id": "GO:0005891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005891", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL84", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "calcium ion transport", "id": "GO:0006816", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006816", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL84", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84" } ], "pmid": "" }, { "name": "chemical synaptic transmission", "id": "GO:0007268", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007268", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL84", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "high voltage-gated calcium channel activity", "id": "GO:0008331", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008331", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PL84", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PL84", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PL84" }, { "id": "SM00072", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00072" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Guanylate kinase/L-type calcium channel beta subunit", "eco_id": "ECO_0000259", "start_pos": 172, "end_pos": 350, "start_aa": "Ser", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 140, "end_pos": 142 }, { "start_pos": 376, "end_pos": 378 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PLG1-1", "uniprot_ac": "A0A8M9PLG1", "uniprot_id": "A0A8M9PLG1_DANRE", "mass": { "chemical_mass": 158426.0, "monoisotopic_mass": 158426.0 }, "refseq": {}, "gene_names": [ { "name": "LOC407643", "type": "recommended", "evidence": [ { "id": "A0A8M9PLG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1" } ] } ], "protein_names": [ { "name": "Alpha-2-macroglobulin-like protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PLG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLG1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC407643", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1", "locus": {} } ], "crossref": [ { "id": "cd02897", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02897", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "407643", "url": "https://www.ncbi.nlm.nih.gov/gene/407643", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002890", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002890", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011625", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011625", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014756", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014756", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036595", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036595", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041555", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041555", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041813", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041813", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047565", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047565", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050473", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050473", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PLG1", "url": "https://www.orthodb.org/?gene=A0A8M9PLG1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11412:SF160", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11412:SF160", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07677", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07677", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07678", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07678", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07703", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07703", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17789", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17789", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17791", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17791", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073779612", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073779612", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLG1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCD0", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCD0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCD0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLLSLLLLLQWSLTSGATDPIYLVAVTSQAVSGSTETLCAQIHEPTEPVSLVVTLRSDVQNMTILQQRSITRDFYTCVTFKVPLVTVESVASINVTIRGQSTFMNKTTQILISPPQKLLFIQSDRPIYKPGQTVKFRIVSLDTKFLPYNQVFKTVELQDPSSNRIGQWLNQSTRSGILDLFHSISPEATQGYYMVTAWDEKNQQISHQFEIKEYVLPKYEVNIDFPSVITAQDNNAPLKVCAKYTYGKALLGTVNVEVCGQSWYYFYERRFPENAGVCNTYSKMTDRTGCASWMINATDFGLINGGNINVQSNVEESGTGVTISGTTTAMFTREYINVYFEDTPDTYKPGMVFKGKVVVTNPQSQPMKNKPVVLSAYYGNQNISLTLITDVNGTVQFSFNTSDWSESSVSLQALFRGVDPTDYMALGYYPSSYLYLRPFHSKSKSFLTLMNPPKKLSCNRDATVVASYIIQGSTLKTGQKTLDFFYIVLSKGSVAQTGRLSVNVNSKKENRGEVTFSLRTAALAPYAQVVVYTILPSGEAVADSVNFPIEECLPNKVSLKFSSPTALPGERASFNLKASPGSLCSVRAIDQSVLLLRPEAELNADSVFGMLPVQFLSGYPYNVEEFELYNCPPSWGGVRGKRSRFYYPYYGNRNDVYEIFRAIGIKIATNSDVKAPVDCSYGIPFVAAKENEVNDVAMPGAAFRPGVMNPNERVRKFFPETWIWDLIPVGNSGSVDVAKTVPDTITTWAAGAFCTSPVGFGLAPSTNLTAFKPFFVSLTLPYSVIREETFTLKASVFNYLSKCIMVKVTLADSTQFTAQPCKGCTYTQCVCAEESKTFQWTITPSVVGKVNFTVRAEAVKTRELCGNEVVTLPNKGKVDTVMQSVLVEVEGTKQSVTQNELICLTDRPYNTSITLALPKVFVKDSAKCFITVLGDLMGRALRNIGDLLAMPYGCGEQNMLQFAPNIYILQYLESSGQLTPEIRARAVTFLQSGYQRELTYKHGDGSYSAFGSNDPSGNTWLTAFVMKSFGGAKRYIFIDQTSIDEAKNWLSQQQKTNGCFTSVGQLIHIEMMGGVNDEVTLSAYITAALLELGVQISDPMVARSLVCLKEASRNITNTYVNALLSYTFTLAGDGEMRLNLLSKLDNQARREGAGRYWSLVNNAQQTSSVEVEMTAYVLLALLSGPSLPRFGLNYSAGIVQWLGRQQNAFGGFSSTQDTVVALQALAKYSAAVFNPEGSIAVTVTSPSGQRNQFTVNRNNRLLYQEKQLTETTGTYKLRAEGKGCVFVQFALNYNIPPPPDALAFNIKTNTGVCSKNQAFTLNVTVRYDGKREETNMVIINVRLLSGFKLDEASLQALKEDPTVKRVDLDEDRVIVYLESLKKKQVKSINLRLQQDVLVQKLKPAVVEVYDYYKTSEMSVTDYTSSCKSIAQ", "length": 1431, "header": "tr|A0A8M9PLG1-1|A0A8M9PLG1_DANRE Isoform 1 of Alpha-2-macroglobulin-like protein 1 isoform X1 OS=Danio rerio OX=7955 GN=LOC407643 PE=3 SV=2 CANONICAL=A0A8M9PLG1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLG1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1/entry#A0A8M9PLG1-1", "sequence": { "sequence": "MLLSLLLLLQWSLTSGATDPIYLVAVTSQAVSGSTETLCAQIHEPTEPVSLVVTLRSDVQNMTILQQRSITRDFYTCVTFKVPLVTVESVASINVTIRGQSTFMNKTTQILISPPQKLLFIQSDRPIYKPGQTVKFRIVSLDTKFLPYNQVFKTVELQDPSSNRIGQWLNQSTRSGILDLFHSISPEATQGYYMVTAWDEKNQQISHQFEIKEYVLPKYEVNIDFPSVITAQDNNAPLKVCAKYTYGKALLGTVNVEVCGQSWYYFYERRFPENAGVCNTYSKMTDRTGCASWMINATDFGLINGGNINVQSNVEESGTGVTISGTTTAMFTREYINVYFEDTPDTYKPGMVFKGKVVVTNPQSQPMKNKPVVLSAYYGNQNISLTLITDVNGTVQFSFNTSDWSESSVSLQALFRGVDPTDYMALGYYPSSYLYLRPFHSKSKSFLTLMNPPKKLSCNRDATVVASYIIQGSTLKTGQKTLDFFYIVLSKGSVAQTGRLSVNVNSKKENRGEVTFSLRTAALAPYAQVVVYTILPSGEAVADSVNFPIEECLPNKVSLKFSSPTALPGERASFNLKASPGSLCSVRAIDQSVLLLRPEAELNADSVFGMLPVQFLSGYPYNVEEFELYNCPPSWGGVRGKRSRFYYPYYGNRNDVYEIFRAIGIKIATNSDVKAPVDCSYGIPFVAAKENEVNDVAMPGAAFRPGVMNPNERVRKFFPETWIWDLIPVGNSGSVDVAKTVPDTITTWAAGAFCTSPVGFGLAPSTNLTAFKPFFVSLTLPYSVIREETFTLKASVFNYLSKCIMVKVTLADSTQFTAQPCKGCTYTQCVCAEESKTFQWTITPSVVGKVNFTVRAEAVKTRELCGNEVVTLPNKGKVDTVMQSVLVEVEGTKQSVTQNELICLTDRPYNTSITLALPKVFVKDSAKCFITVLGDLMGRALRNIGDLLAMPYGCGEQNMLQFAPNIYILQYLESSGQLTPEIRARAVTFLQSGYQRELTYKHGDGSYSAFGSNDPSGNTWLTAFVMKSFGGAKRYIFIDQTSIDEAKNWLSQQQKTNGCFTSVGQLIHIEMMGGVNDEVTLSAYITAALLELGVQISDPMVARSLVCLKEASRNITNTYVNALLSYTFTLAGDGEMRLNLLSKLDNQARREGAGRYWSLVNNAQQTSSVEVEMTAYVLLALLSGPSLPRFGLNYSAGIVQWLGRQQNAFGGFSSTQDTVVALQALAKYSAAVFNPEGSIAVTVTSPSGQRNQFTVNRNNRLLYQEKQLTETTGTYKLRAEGKGCVFVQFALNYNIPPPPDALAFNIKTNTGVCSKNQAFTLNVTVRYDGKREETNMVIINVRLLSGFKLDEASLQALKEDPTVKRVDLDEDRVIVYLESLKKKQVKSINLRLQQDVLVQKLKPAVVEVYDYYKTSEMSVTDYTSSCKSIAQ", "length": 1431, "header": "tr|A0A8M9PLG1-1|A0A8M9PLG1_DANRE Isoform 1 of Alpha-2-macroglobulin-like protein 1 isoform X1 OS=Danio rerio OX=7955 GN=LOC407643 PE=3 SV=2 CANONICAL=A0A8M9PLG1-1" }, "locus": {} }, { "isoform_ac": "A0AC58HCD0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1/entry#A0AC58HCD0-1", "sequence": { "sequence": "MTILQQRSITRDFYTCVTFKVPLVTVESVASINVTIRGQSTFMNKTTQILISPPQKLLFIQSDRPIYKPGQTVKFRIVSLDTKFLPYNQVFKTVELQDPSSNRIGQWLNQSTRSGILDLFHSISPEATQGYYMVTAWDEKNQQISHQFEIKEYVLPKYEVNIDFPSVITAQDNNAPLKVCAKYTYGKALLGTVNVEVCGQSWYYFYERRFPENAGVCNTYSKMTDRTGCASWMINATDFGLINGGNINVQSNVEESGTGVTISGTTTAMFTREYINVYFEDTPDTYKPGMVFKGKVVVTNPQSQPMKNKPVVLSAYYGNQNISLTLITDVNGTVQFSFNTSDWSESSVSLQALFRGVDPTDYMALGYYPSSYLYLRPFHSKSKSFLTLMNPPKKLSCNRDATVVASYIIQGSTLKTGQKTLDFFYIVLSKGSVAQTGRLSVNVNSKKENRGEVTFSLRTAALAPYAQVVVYTILPSGEAVADSVNFPIEECLPNKVSLKFSSPTALPGERASFNLKASPGSLCSVRAIDQSVLLLRPEAELNADSVFGMLPVQFLSGYPYNVEEFELYNCPPSWGGVRGKRSRFYYPYYGNRNDVYEIFRAIGIKIATNSDVKAPVDCSYGIPFVAAKENEVNDVAMPGAAFRPGVMNPNERVRKFFPETWIWDLIPVGNSGSVDVAKTVPDTITTWAAGAFCTSPVGFGLAPSTNLTAFKPFFVSLTLPYSVIREETFTLKASVFNYLSKCIMVKVTLADSTQFTAQPCKGCTYTQCVCAEESKTFQWTITPSVVGKVNFTVRAEAVKTRELCGNEVVTLPNKGKVDTVMQSVLVEVEGTKQSVTQNELICLTDRPYNTSITLALPKVFVKDSAKCFITVLGDLMGRALRNIGDLLAMPYGCGEQNMLQFAPNIYILQYLESSGQLTPEIRARAVTFLQSGYQRELTYKHGDGSYSAFGSNDPSGNTWLTAFVMKSFGGAKRYIFIDQTSIDEAKNWLSQQQKTNGCFTSVGQLIHIEMMGGVNDEVTLSAYITAALLELGVQISDPMVARSLVCLKEASRNITNTYVNALLSYTFTLAGDGEMRLNLLSKLDNQARREGAGRYWSLVNNAQQTSSVEVEMTAYVLLALLSGPSLPRFGLNYSAGIVQWLGRQQNAFGGFSSTQDTVVALQALAKYSAAVFNPEGSIAVTVTSPSGQRNQFTVNRNNRLLYQEKQLTETTGTYKLRAEGKGCVFVQFALNYNIPPPPDALAFNIKTNTGVCSKNQAFTLNVTVRYDGKREETNMVIINVRLLSGFKLDEASLQALKEDPTVKRVDLDEDRVIVYLESLKKKQVKSINLRLQQDVLVQKLKPAVVEVYDYYKTSEMSVTDYTSSCKSIAQ", "length": 1370, "header": "tr|A0AC58HCD0-1|A0AC58HCD0_DANRE Computationally mapped isoform of Alpha-2-macroglobulin-like protein 1 isoform X2 OS=Danio rerio OX=7955 GN=LOC407643 PE=3 SV=1 CANONICAL=A0A8M9PLG1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase inhibitor activity", "id": "GO:0004867", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004867", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLG1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLG1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLG1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1114, "end_pos": 1116, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1193, "end_pos": 1195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1322, "end_pos": 1324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 392, "end_pos": 394, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" }, { "start_pos": 767, "end_pos": 769, "annotation": "n_glycosylation_sequon" }, { "start_pos": 851, "end_pos": 853, "annotation": "n_glycosylation_sequon" }, { "start_pos": 910, "end_pos": 912, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PLG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1" }, { "id": "SM01360", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01360" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-2-macroglobulin", "eco_id": "ECO_0000259", "start_pos": 721, "end_pos": 810, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PLG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1" }, { "id": "SM01359", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01359" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-2-macroglobulin bait region", "eco_id": "ECO_0000259", "start_pos": 447, "end_pos": 596, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PLG1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLG1" }, { "id": "SM01361", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01361" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-macroglobulin receptor-binding", "eco_id": "ECO_0000259", "start_pos": 1334, "end_pos": 1422, "start_aa": "Thr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 105, "end_pos": 107 }, { "start_pos": 1114, "end_pos": 1116 }, { "start_pos": 1193, "end_pos": 1195 }, { "start_pos": 1322, "end_pos": 1324 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 382, "end_pos": 384 }, { "start_pos": 392, "end_pos": 394 }, { "start_pos": 400, "end_pos": 402 }, { "start_pos": 61, "end_pos": 63 }, { "start_pos": 767, "end_pos": 769 }, { "start_pos": 851, "end_pos": 853 }, { "start_pos": 910, "end_pos": 912 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPK9-1", "uniprot_ac": "A0A8M9PPK9", "uniprot_id": "A0A8M9PPK9_DANRE", "mass": { "chemical_mass": 97678.0, "monoisotopic_mass": 97678.0 }, "refseq": { "ac": "XP_021323125", "name": "protein EFR3 homolog B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323125" }, "gene_names": [ { "name": "efr3ba", "type": "recommended", "evidence": [ { "id": "A0A8M9PPK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPK9" } ] }, { "name": "efr3ba", "type": "synonym", "evidence": [ { "id": "XP_021323125", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323125" } ] } ], "protein_names": [ { "name": "Protein EFR3 homolog B isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PPK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPK9/entry#names_and_taxonomy" } ] }, { "name": "protein EFR3 homolog B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323125", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323125" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323125.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323125", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323125" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPK9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPK9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "efr3ba", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPK9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030616-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-64", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PPK9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PPK9", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000033516", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000033516", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "560858", "url": "https://www.ncbi.nlm.nih.gov/gene/560858", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:560858", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560858", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QCEARAN", "url": "https://omabrowser.org/oma/group/QCEARAN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PPK9", "url": "https://www.orthodb.org/?gene=A0A8M9PPK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1QTD4", "url": "https://www.orthodb.org/?gene=F1QTD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12444", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12444", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12444:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12444:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF21052", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21052", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323125", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323125", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLI5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPK9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPF3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPF3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QTD4", "url": "https://www.uniprot.org/uniprotkb/F1QTD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QTD4-1", "url": "https://www.uniprot.org/uniprotkb/F1QTD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030616-64", "url": "https://zfin.org/ZDB-GENE-030616-64", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKVYRSITRVDIILSGFDENKKMPLPSLRNFSALPDFPGPRRLLLDCSALLDHQVGGGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKANMEKLTFYALSAPEKLDRIGAYLSERLSRDVARHRYGYVCIAMEALDQLLMACHCQSINLFVESFLTMVRKLLEADKPNLQILGTNSFVKFANIEEDTASYHRSYDFFVSRFSEMCHSSFEDPDIRTKIRMAGIRGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQQEEGIERSPSPETEKEKESPVELTERCFRELLGRAVYGNIKNAVKPVLMHLDNHSLWEGKTFAVRCFKIIMYSIQSQHSHLVIQQLLGHLDANSKNSARVRAGIVEVISEAAVIEASGSIGPTVLEVFNTLLKQLRLSVDYELTGSYDSFANMGTKVIKVHEERQLQESVIKTIGSFANTLPTYQRSEVMLFIIGKIPVPGMYPALGSANTGVEGSRMIQIMLLKSLLQVTAGFQSNNILTALPTSFLDPLLSFTLMEDAEIRLLVLDILISIIDRHDNRHKFSPVRIISDISILKLKVDKCSRQDNLFMKKHSHRLYRHIYLACKEDSSVQRHFESLHTLLGLICVELANEEVVVDLIRLALALQDLALTDDTLPVYSRCAIHALSAAYLNLISQLTTVPTFCQHVHEVIESRKKLVPFLLPEDVLVESPKIPEKLEKVEGEMLFAQAKIAEMLGGSGYNTERLATAYIPQITDEDRLSKRKSIGDTVSLQLEMESRNSPEKEQRSTAEQITFETLKQAIVDSVNVEELERERRRQVVERFQTAPFEEIAAHCGARSSLLQSKLNQIFEITIRPPPSPSGSVGNGHGRSRSVPVYEMKFPDLCVY", "length": 866, "header": "tr|A0A8M9PPK9-1|A0A8M9PPK9_DANRE Isoform 1 of Protein EFR3 homolog B isoform X1 OS=Danio rerio OX=7955 GN=efr3ba PE=3 SV=2 CANONICAL=A0A8M9PPK9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPK9/entry#A0A8M9PLI5-1", "sequence": { "sequence": "MKVYRSITRVDIILSGFDENKKMPLPSLRNFSALPDFPGPRRLLLDCSALLDHQVGGGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKANMEKLTFYALSAPEKLDRIGAYLSERLSRDVARHRYGYVCIAMEALDQLLMACHCQSINLFVESFLTMVRKLLEADKPNLQILGTNSFVKFANIEEDTASYHRSYDFFVSRFSEMCHSSFEDPDIRTKIRMAGIRGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQQEEGIERSPSPETEKEKESPVELTERCFRELLGRAVYGNIKNAVKPVLMHLDNHSLWEGKTFAVRCFKIIMYSIQSQHSHLVIQQLLGHLDANSKNSARVRAGIVEVISEAAVIEASGSIGPTVLEVFNTLLKQLRLSVDYELTGSYDSFANMGTKVIKVHEERQLQESVIKTIGSFANTLPTYQRSEVMLFIIGKIPVPGMYPALGSANTGVEGSRMIQIMLLKSLLQVTAGFQSNNILTALPTSFLDPLLSFTLMEDAEIRLLVLDILISIIDRHDNRHKFSPVRIISDISILKLKVDKCSRQDNLFMKKHSHRLYRHIYLACKEDSSVQRHFESLHTLLGLICVELANEEVVVDLIRLALALQDLALTDDTLPVYSRCAIHALSAAYLNLISQLTTVPTFCQHVHEVIESRKKLVPFLLPEDVLVESPKIPEKLEKVEGEMLFAQAKIAEMLGGSGYNTERLATAYIPQITDEDRLSKRKSIGDTVSLQLEMESRNSPEKEQRSTAEQITFETLKQAIDSVNVEELERERRRQVVERFQTAPFEEIAAHCGARSSLLQSKLNQIFEITIRPPPSPSGSVGNGHGRSRSVPVYEMKFPDLCVY", "length": 865, "header": "tr|A0A8M9PLI5-1|A0A8M9PPK9_DANRE Computationally mapped isoform of Protein EFR3 homolog B isoform X1 OS=Danio rerio OX=7955 GN=efr3ba PE=3 SV=2 CANONICAL=A0A8M9PPK9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PPK9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPK9/entry#A0A8M9PPK9-1", "sequence": { "sequence": "MKVYRSITRVDIILSGFDENKKMPLPSLRNFSALPDFPGPRRLLLDCSALLDHQVGGGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKANMEKLTFYALSAPEKLDRIGAYLSERLSRDVARHRYGYVCIAMEALDQLLMACHCQSINLFVESFLTMVRKLLEADKPNLQILGTNSFVKFANIEEDTASYHRSYDFFVSRFSEMCHSSFEDPDIRTKIRMAGIRGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQQEEGIERSPSPETEKEKESPVELTERCFRELLGRAVYGNIKNAVKPVLMHLDNHSLWEGKTFAVRCFKIIMYSIQSQHSHLVIQQLLGHLDANSKNSARVRAGIVEVISEAAVIEASGSIGPTVLEVFNTLLKQLRLSVDYELTGSYDSFANMGTKVIKVHEERQLQESVIKTIGSFANTLPTYQRSEVMLFIIGKIPVPGMYPALGSANTGVEGSRMIQIMLLKSLLQVTAGFQSNNILTALPTSFLDPLLSFTLMEDAEIRLLVLDILISIIDRHDNRHKFSPVRIISDISILKLKVDKCSRQDNLFMKKHSHRLYRHIYLACKEDSSVQRHFESLHTLLGLICVELANEEVVVDLIRLALALQDLALTDDTLPVYSRCAIHALSAAYLNLISQLTTVPTFCQHVHEVIESRKKLVPFLLPEDVLVESPKIPEKLEKVEGEMLFAQAKIAEMLGGSGYNTERLATAYIPQITDEDRLSKRKSIGDTVSLQLEMESRNSPEKEQRSTAEQITFETLKQAIVDSVNVEELERERRRQVVERFQTAPFEEIAAHCGARSSLLQSKLNQIFEITIRPPPSPSGSVGNGHGRSRSVPVYEMKFPDLCVY", "length": 866, "header": "tr|A0A8M9PPK9-1|A0A8M9PPK9_DANRE Isoform 1 of Protein EFR3 homolog B isoform X1 OS=Danio rerio OX=7955 GN=efr3ba PE=3 SV=2 CANONICAL=A0A8M9PPK9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HPF3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPK9/entry#A0AC58HPF3-1", "sequence": { "sequence": "MYGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKANMEKLTFYALSAPEKLDRIGAYLSERLSRDVARHRYGYVCIAMEALDQLLMACHCQSINLFVESFLTMVRKLLEADKPNLQILGTNSFVKFANIEEDTASYHRSYDFFVSRFSEMCHSSFEDPDIRTKIRMAGIRGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQQEEGIERSPSPETEKEKESPVELTERCFRELLGRAVYGNIKNAVKPVLMHLDNHSLWEGKTFAVRCFKIIMYSIQSQHSHLVIQQLLGHLDANSKNSARVRAGIVEVISEAAVIEASGSIGPTVLEVFNTLLKQLRLSVDYELTGSYDSFANMGTKVIKVHEERQLQESVIKTIGSFANTLPTYQRSEVMLFIIGKIPVPGMYPALGSANTGVEGSRMIQIMLLKSLLQVTAGFQSNNILTALPTSFLDPLLSFTLMEDAEIRLLVLDILISIIDRHDNRHKFSPVRIISDISILKLKVDKCSRQDNLFMKKHSHRLYRHIYLACKEDSSVQRHFESLHTLLGLICVELANEEVVVDLIRLALALQDLALTDDTLPVYSRCAIHALSAAYLNLISQLTTVPTFCQHVHEVIESRKKLVPFLLPEDVLVESPKIPEKLEKVEGEMLFAQAKIAEMLGGSGYNTERLATAYIPQITDEDRLSKRKSIGDTVSLQLEMESRNSPEKEQRSTAEQITFETLKQAIDSVNVEELERERRRQVVERFQTAPFEEIAAHCGARSSLLQSKLNQIFEITIRPPPSPSGSVGNGHGRSRSVPVYEMKFPDLCVY", "length": 810, "header": "tr|A0AC58HPF3-1|A0AC58HPF3_DANRE Computationally mapped isoform of Protein EFR3 homolog B isoform X4 OS=Danio rerio OX=7955 GN=efr3ba PE=3 SV=1 CANONICAL=A0A8M9PPK9-1" }, "locus": {} }, { "isoform_ac": "F1QTD4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPK9/entry#F1QTD4-1", "sequence": { "sequence": "MYGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKANMEKLTFYALSAPEKLDRIGAYLSERLSRDVARHRYGYVCIAMEALDQLLMACHCQSINLFVESFLTMVRKLLEADKPNLQILGTNSFVKFANIEEDTASYHRSYDFFVSRFSEMCHSSFEDPDIRTKIRMAGIRGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQQEEGIERSPSPETEKEKESPVELTERCFRELLGRAVYGNIKNAVKPVLMHLDNHSLWEGKTFAVRCFKIIMYSIQSQHSHLVIQQLLGHLDANSKNSARVRAGIVEVISEAAVIEASGSIGPTVLEVFNTLLKQLRLSVDYELTGSYDSFANMGTKVIKVHEERQLQESVIKTIGSFANTLPTYQRSEVMLFIIGKIPVPGMYPALGSANTGVEGSRMIQIMLLKSLLQVTAGFQSNNILTALPTSFLDPLLSFTLMEDAEIRLLVLDILISIIDRHDNRHKFSPVRIISDISILKLKVDKCSRQDNLFMKKHSHRLYRHIYLACKEDSSVQRHFESLHTLLGLICVELANEEVVVDLIRLALALQDLALTDDTLPVYSRCAIHALSAAYLNLISQLTTVPTFCQHVHEVIESRKKLVPFLLPEDVLVESPKIPEKLEKVEGEMLFAQAKIAEMLGGSGYNTERLATAYIPQITDEDRLSKRKSIGDTVSLQLEMESRNSPEKEQRSTAEQITFETLKQAIVDSVNVEELERERRRQVVERFQTAPFEEIAAHCGARSSLLQSKLNQIFEITIRPPPSPSGSVGNGHGRSRSVPVYEMKFPDLCVY", "length": 811, "header": "tr|F1QTD4-1|F1QTD4_DANRE Computationally mapped isoform of Protein EFR3 homolog B isoform X3 OS=Danio rerio OX=7955 GN=efr3ba PE=3 SV=2 CANONICAL=A0A8M9PPK9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 383, "start_aa": "Thr", "end_pos": 383, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr383", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:560858", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560858", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZM57-1", "protein_name": "Protein EFR3 homolog B", "gene_name": "Efr3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQAPEKEKENPAELAERCLRELLGRAAFGNIKNAIKPVLIHLDNHSLWEPKVFATRCFKIIMYSIQPQHSHLVIQQLLSHLDANSRSAATVRAGIVEVLSEAAVIAATGSVGPTVLEMFNTLLRQLRLSIDYALTGSYDGAVSLGTKIIKEHEERMFQEAVIKTIGSFASTLPTYQRSEVILFIMSKVPLPSLHHPVETGRTGENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTALMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLGDISVLKLKVDKCSRQDTVFMKKHSQQLYRHIYLSCKEETNIQKHYEALYGLLALISIELANEEVVVDLIRLVLAVQDVAQVNEENLPAYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAPYMLPEDVFVEKPRLAQNLDGVVIEFLFRQSKISEVLGGSGYNADRLCLPYIPQLTDEDRLSKRKSIGETISLQVEVESRNSPEKEERVPAEEITYETLKKAIVDSVAVEEQERERRRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIFEITIRPPPSPSGTISAAYGQPQNHSIPVYEMKFPDLCVY", "length": 817 }, "evidence": [ { "id": "FB:FBgn0086784", "url": "https://alliancegenome.org/gene/FB:FBgn0086784#orthology", "database": "AGR" }, { "id": "MGI:2444851", "url": "https://alliancegenome.org/gene/MGI:2444851#orthology", "database": "AGR" }, { "id": "HGNC:29155", "url": "https://alliancegenome.org/gene/HGNC:29155#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-64#orthology", "database": "AGR" }, { "id": "RGD:1310845", "url": "https://alliancegenome.org/gene/RGD:1310845#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4ADS9-1", "protein_name": "Protein EFR3 homolog A", "gene_name": "Efr3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTRVCCCCSALRPRYKRLVDNIFPEDPKDGLVKADMEKLTFYAVSAPEKLDRIGAYLAERLSRDVVRHRSGYVLIAMEALDQLLMACHSQSIKPFVESFLHMVAKLLESGEPKLQVLGTNSFVKFANIEEDTPSYHRRYDFFVSRFSAMCHSCHSDPEIRTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQKIEEVDSRLGPPSSPSAADKEENPAVLAESCFRELLGRATFGNMNNAVRPVFAHLDHHKLWDPNEFAVHCFKIIMYSIQAQYSHHVIQEILGHLDARKKDSPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLKHLRLSVELEASDSQKGSVGSVSLSSKDNDEKIVQNAVIQTIGFFGSNLPDYQRSEIMMFIMGKVPVFGTSTHTLDISQLGDLGTRRIQIMLLRSLLMVTSGYKAKTIVTALPGSFLDPLLSPSLMEDYELRQLVLEVMHNLMDRHDNRAKLRGIRIIPDVADLKIKREKICRQDTSFMKKNGQQLYRHIYLGCKEEDNVQKNYELLYTSLALITIELANEEVVIDLIRLAIALQDSAIINEDNLPMFHRCGIMALVAAYLNFVSQMIAVPAFCQHVSKVIETRTMEAPYFLPEHIFRDKCMLPKSLEKHDKNLYFLTNKIAESLGGSGYSVERLSVPYVPQVTDEDRLSRRKSIVDTVSIQVDILSNSVPSDDVVSNTEEITFEALKKAIDTNGMEEQEKEKRRLVIEKFQKAPFEEIAAQCESKANLLHDRLAQILELTIRPPPSPSGTLTVTSGHAQYQSVPVYEMKFPDLCVY", "length": 819 }, "evidence": [ { "id": "FB:FBgn0086784", "url": "https://alliancegenome.org/gene/FB:FBgn0086784#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q03653-1", "protein_name": "Protein EFR3", "gene_name": "EFR3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MQLSMRMMFTPKHQKLVNQCYPTGRTTDKKPKSSETSYLLYYVNSRRSKLEKVSTYLIKRSTSDLNHRRIGNIAVTLDLMNKIVLHCKENLNVFVKDFLYIMNKVLSNNNFNNDVSVVELIELAFSSICQNLDDVLCNGDMEFVQLYQNFVDLFFKIVTERIHNDDMLLKCCIDISNTNSVSSNPQLNHFVSKSVAYTISKFQERNPKFKTLSLEAALESNLGKRLSRTQTRTIGLDKAAEDNHDLSVKALQSYFNTTETDKLNLSIRTLLRCLQSTPNKELLEFVCNGIPVQLRYIVILLLVRQLSDKDKNVNPIVSLKLMSSLLVSDVSIVGLSVLDIMRKLLNFQLKNATNKEVVAQSCITMTDLNHKTYYAEQTSDMLYELLLKLKSDTVKDVEKNAVVEDIDFLVEHITQPSISLELFIDLAHYMKNHIICLFNIVETEVPSSILFSKLYSLLRELDSHGVQKEMMEEIFDKYGKMALLSGLNYFLENVSEPEYTYYSYHLQAANFLKLNDYKSQTEYKMQTRTLFTKEDLLSYYSDTGSNKYSKKGAQILLSRDNQISTSDLLSDSQVRTTPLEYKNVPNAIFSNGKAVYDNNDFAAKQNKFDNSIDDNIEEANDTVISDANAKGSIYRFVAEDARSWKTMRATAPKVSDLKKTMNEKNIPNNMKRDGSFRGSQSVKSRVTNITFLLNELKTFSDDANKIKDPDEENIVGLDKIDVARSNSLRLAPISSLSDRSSIGNRKSFLQKTATGENQNDDFKDANEDLHSLSSRGKIFSST", "length": 782 }, "evidence": [ { "id": "FB:FBgn0086784", "url": "https://alliancegenome.org/gene/FB:FBgn0086784#orthology", "database": "AGR" }, { "id": "MGI:2444851", "url": "https://alliancegenome.org/gene/MGI:2444851#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q14156-1", "protein_name": "Protein EFR3 homolog A", "gene_name": "EFR3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPTRVCCCCSALRPRYKRLVDNIFPEDPKDGLVKTDMEKLTFYAVSAPEKLDRIGSYLAERLSRDVVRHRSGYVLIAMEALDQLLMACHSQSIKPFVESFLHMVAKLLESGEPKLQVLGTNSFVKFANIEEDTPSYHRRYDFFVSRFSAMCHSCHSDPEIRTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQKIEEVDSRIGPPSSPSATDKEENPAVLAENCFRELLGRATFGNMNNAVRPVFAHLDHHKLWDPNEFAVHCFKIIMYSIQAQYSHHVIQEILGHLDARKKDAPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLKHLRLSVEFEANDLQGGSVGSVNLNTSSKDNDEKIVQNAIIQTIGFFGSNLPDYQRSEIMMFIMGKVPVFGTSTHTLDISQLGDLGTRRIQIMLLRSLLMVTSGYKAKTIVTALPGSFLDPLLSPSLMEDYELRQLVLEVMHNLMDRHDNRAKLRGIRIIPDVADLKIKREKICRQDTSFMKKNGQQLYRHIYLGCKEEDNVQKNYELLYTSLALITIELANEEVVIDLIRLAIALQDSAIINEDNLPMFHRCGIMALVAAYLNFVSQMIAVPAFCQHVSKVIEIRTMEAPYFLPEHIFRDKCMLPKSLEKHEKDLYFLTNKIAESLGGSGYSVERLSVPYVPQVTDEDRLSRRKSIVDTVSIQVDILSNNVPSDDVVSNTEEITFEALKKAIDTSGMEEQEKEKRRLVIEKFQKAPFEEIAAQCESKANLLHDRLAQILELTIRPPPSPSGTLTITSGHAQYQSVPVYEMKFPDLCVY", "length": 821 }, "evidence": [ { "id": "FB:FBgn0086784", "url": "https://alliancegenome.org/gene/FB:FBgn0086784#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5SPP5-1", "protein_name": "Protein EFR3 homolog B", "gene_name": "efr3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKANMEKLTFYALSAPEKLDRIGAYLSERLSRDVARHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVRKLLEADKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSGYEDPDIRTKIRMAGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQSGEGTESRSPSPLQASEKEKESPAELTERCFRELLGRAAYGNIKNAVTPVLMHLDNHSLWEGKTFAVRCFKIIMYSIQSQHSHLVIQQLLGHLDANSKSSATVRAGIVEVLLEVAAIAASGSVGPTVLEVFNTLLRHLRLSVDYELTGSYDCTNIGTKIIKEHEERQLQEAVIRTIGSFANTLPTYQRSEVMLFIMGKVPIPGLHPTLPSIGSGPEGNRMIQVMLLKSLRQVTCGFQTTNMLTALPNSFLDPMLSFALLEDAEIRLLVLEILVSLIDRHDNLPKFSNISIISDISVLKLKVDKCSRQDNLFMKKHAQHLYRHIYLCSKEQSSVQPHFEKLYSLLALISMELANEEVVVDLIRVALALQDLALSSEEMLPVYNRCAIHALSSAYLNLISQLTTVPAFCQHVHEVIEMRQKEIPYLLPEDVFIENPKIPKTLEKLEGDVLFQQAKITEVLGGSGYNTERLATPYVPQFTDEDRLSKRKSIGETISLQVEVDSRNSPEKEERTPAEEITFETLKNAIVDSVGVEEQEKERRRQVVEKFQKAPFEEIAAHCGARATMLQSKLNQIFEITIRPPPSPSGTITSSYGQTQSRSVPVYEMKFPDLCVY", "length": 816 }, "evidence": [ { "id": "FB:FBgn0086784", "url": "https://alliancegenome.org/gene/FB:FBgn0086784#orthology", "database": "AGR" }, { "id": "MGI:2444851", "url": "https://alliancegenome.org/gene/MGI:2444851#orthology", "database": "AGR" }, { "id": "HGNC:29155", "url": "https://alliancegenome.org/gene/HGNC:29155#orthology", "database": "AGR" }, { "id": "RGD:1310845", "url": "https://alliancegenome.org/gene/RGD:1310845#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZQ18-1", "protein_name": "Protein EFR3 homolog B", "gene_name": "Efr3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQAPEKEKENPAELAERCLRELLGRAAFGNIKNAIKPVLIHLDNHSLWEPKVFATRCFKIIMYSIQPQHSHLVIQQLLSHLDANSRSAATVRAGIVEVLSEAAIIAATGSVGPTVLEMFNTLLRQLRLSIDYALTGSYDGAVSLGSKIIKEHEECMFQEAVIKTIGSFASTLPTYQRSEVILFIMSKVPLPSVHHPVETGRTGENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTALMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLGDISVLKLKVDKCSRQDTVFMKKHSQQLYRHIYLSCKEETNIQKHYEALYGLLALISIELANEEVVVDLIRLVLAVQDVAQVNEENLPTYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAPYMLPEDVFVEKPRLSQNLDGVVIEFLFRQSKISEVLGGSGYNSDRLCLPYIPQLTDEDRLSKRKSIGETISLQVEVESRNSPEKEERVPAEEITYETLKKAIVDSVAVEEQERERQRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIFEITIRPPPSPSGTISAAYGQPQNHSIPVYEMKFPDLCVY", "length": 817 }, "evidence": [ { "id": "FB:FBgn0086784", "url": "https://alliancegenome.org/gene/FB:FBgn0086784#orthology", "database": "AGR" }, { "id": "MGI:2444851", "url": "https://alliancegenome.org/gene/MGI:2444851#orthology", "database": "AGR" }, { "id": "HGNC:29155", "url": "https://alliancegenome.org/gene/HGNC:29155#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-64#orthology", "database": "AGR" }, { "id": "RGD:1310845", "url": "https://alliancegenome.org/gene/RGD:1310845#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BG67-1", "protein_name": "Protein EFR3 homolog A", "gene_name": "Efr3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTRVCCCCSALRPRYKRLVDNIFPEDPKDGLVKADMEKLTFYAVSAPEKLDRIGAYLAERLSRDVVRHRSGYVLIAMEALDQLLMACHSQSIKPFVESFLHMVAKLLESGEPKLQVLGTNSFVKFANIEEDTPSYHRRYDFFVSRFSAMCHSCHSDPEIRTEIRIAGIRGIQGVVRKTVNDELRATIWEPQHMDKIVPSLLFNMQKIEEVDSRLGPPSSPSAADKEENPAVLAESCFRELLGRATFGNMNNAVRPVFAHLDHHKLWDPNEFAVHCFKIIMYSIQAQYSHHVIQEILGHLDARRKDSPRVRAGIIQVLLEAVAIAAKGSIGPTVLEVFNTLLKHLRLSVELEANDSQKGSVGSVTVSSKDNDEKIVQNAVIQTIGFFGSNLPDYQRSEIMMFIMGKVPVFGTSTHTLDISQLGDLGTRRIQIMLLRSLLMVTSGYKAKTIVTALPGSFLDPLLSPSLMEDYELRQLVLEVMHNLMDRHDNRAKLRGIRIIPDVADLKIKREKICRQDTSFMKKNGQQLYRHIYLGCKEEDNVQKNYELLYTSLALITIELANEEVVIDLIRLAIALQDSAIINEDNLSMFHRCGIMALVAAYLNFVSQMIAVPAFCQHVSKVIETRTMEAPYFLPEHIFRDKCMLPKSLEKHDKNLYFLTNKIAESLGGSGYSVERLTVPYVPQVTDEDRLSRRKSIVDTVSIQVDILSNSVPSDDVVSNTEEITFEALKKAIDTNGMEEQEKEKRRLVIEKFQKAPFEEIAAQCESKANLLHDRLAQILELTIRPPPSPSGTLTVTSGHTQYQSVPVYEMKFPDLCVY", "length": 819 }, "evidence": [ { "id": "FB:FBgn0086784", "url": "https://alliancegenome.org/gene/FB:FBgn0086784#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IGJ0-2", "protein_name": "Protein EFR3 homolog cmp44E", "gene_name": "stmA", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALIRCCFEPPELPEFFDSFVQKCTDPSCCCGCCSALRPRYKRLVDNIFPVNPEDGLVKSNMEKLTFYSLSSPDKLDRIGEYLYQKATKDINRKRYKLAEIAMEAMDLLLQACHAQTTLNLFVESFLRMVQKLLEDSNPNLKIMATNSFVKFANINEDTPSYHRRYDFFISKFSSMCHSDAASMRDSLRLAGIKGLQGVIRKTVSDDLVENIWEAEHMEKIVPSLLFNMQFCVNVMFVKKNLLASGDLTPVEDATNVTPPALAEEVLRELVGRASFGHIRSVLKPLLTHLDRHELWVPNTFAIHTFRIVMISIQPQYSYTVVETLMQHLDNNFKSSPKTRTSLAVVLSKIIAIAAGESVGPSALDIINNLLTHLRTSVSTTSEITPEESQYQEALINALGEFANHHPDYQKIEIMLFIMNTVPDLSKKSKGDQMLQNILLKSLLKVGTQYSTVSFEKAFPASFLQPLLKMARAPHNPTRMVVMQILQALLDRHQNEQVLSSVSVKPYPALSQEPPSRSDIIFTHKYGANIMQALIDSMALSDRVDALTSSFNTAALLIVEMSCNETVQEFLLFILGIQQVACTVDTLGNVHKCSLHAISIGLLVLISRVSGINNLLEYAQKIVDARREEASHFLPPLLEPKKLAGKTFNLQLPHLAIDKLALGECLQNAGMDAQRLNTGAPYSLNQTDHPGHRHSWVESVSNQLTQRNSSADLTVYNGDVDSVSSSPGVCKKLLAPEFNFDAMKRALAEPTEAAKREQRERQMQIVRTFREGEFDDLMRRTEPKHDLIQNRLNELFNSLAVERQITQSDTKSSQLQASNEKPIYETNFPELFYY", "length": 834 }, "evidence": [ { "id": "FB:FBgn0086784", "url": "https://alliancegenome.org/gene/FB:FBgn0086784#orthology", "database": "AGR" }, { "id": "MGI:2444851", "url": "https://alliancegenome.org/gene/MGI:2444851#orthology", "database": "AGR" }, { "id": "HGNC:29155", "url": "https://alliancegenome.org/gene/HGNC:29155#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-64#orthology", "database": "AGR" }, { "id": "RGD:1310845", "url": "https://alliancegenome.org/gene/RGD:1310845#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y2G0-1", "protein_name": "Protein EFR3 homolog B", "gene_name": "EFR3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYGVCGCCGALRPRYKRLVDNIFPEDPEDGLVKTNMEKLTFYALSAPEKLDRIGAYLSERLIRDVGRHRYGYVCIAMEALDQLLMACHCQSINLFVESFLKMVAKLLESEKPNLQILGTNSFVKFANIEEDTPSYHRSYDFFVSRFSEMCHSSHDDLEIKTKIRMSGIKGLQGVVRKTVNDELQANIWDPQHMDKIVPSLLFNLQHVEEAESRSPSPLQAPEKEKESPAELAERCLRELLGRAAFGNIKNAIKPVLIHLDNHSLWEPKVFAIRCFKIIMYSIQPQHSHLVIQQLLGHLDANSRSAATVRAGIVEVLSEAAVIAATGSVGPTVLEMFNTLLRQLRLSIDYALTGSYDGAVSLGTKIIKEHEERMFQEAVIKTVGSFASTLPTYQRSEVILFIMSKVPRPSLHQAVDTGRTGENRNRLTQIMLLKSLLQVSTGFQCNNMMSALPSNFLDRLLSTALMEDAEIRLFVLEILISFIDRHGNRHKFSTISTLSDISVLKLKVDKCSRQDTVFMKKHSQQLYRHIYLSCKEETNVQKHYEALYGLLALISIELANEEVVVDLIRLVLAVQDVAQVNEENLPVYNRCALYALGAAYLNLISQLTTVPAFCQHIHEVIETRKKEAPYMLPEDVFVERPRLSQNLDGVVIELLFRQSKISEVLGGSGYNSDRLCLPYIPQLTDEDRLSKRRSIGETISLQVEVESRNSPEKEERVPAEEITYETLKKAIVDSVAVEEQERERRRQVVEKFQKAPFEEIAAHCGARASLLQSKLNQIFEITIRPPPSPSGTITAAYGQPQNHSIPVYEMKFPDLCVY", "length": 817 }, "evidence": [ { "id": "FB:FBgn0086784", "url": "https://alliancegenome.org/gene/FB:FBgn0086784#orthology", "database": "AGR" }, { "id": "MGI:2444851", "url": "https://alliancegenome.org/gene/MGI:2444851#orthology", "database": "AGR" }, { "id": "HGNC:29155", "url": "https://alliancegenome.org/gene/HGNC:29155#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-64#orthology", "database": "AGR" }, { "id": "RGD:1310845", "url": "https://alliancegenome.org/gene/RGD:1310845#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPK9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPK9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to plasma membrane", "id": "GO:0072659", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0072659", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPK9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPK9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 383 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 }, { "start_pos": 313, "end_pos": 315 } ] }, "class_list": [], 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Classification", "Other" ] }, { "id": "XP_021332342", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332342", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEIKKEPYRIKVEATKKQTGPVKVNEVRRNHFKNPRNITKENKNADASQTVHRQGQKPGVNGHYNCSACGKIYKHKSGFYRHKRFHTGKGLFTCTQCGKDFPEKGKLDIHMRIHTGERPFTCAQCGQSFIHKPDLTRHMRIHTGERPYTCTQCGKSFIDPSCLKAHSNKHIEEKPFTCAQCGKGFLYQFILNNHLLSHSGVKPFSCHQCDKTFVLEKRLKEHLQVHAAVKPHVCFCGKSFIIMNRLQDHQRIHTGEGPYKCSHCGKSFIYFKSLKTHERNHTGKKP", "length": 286, "header": "tr|A0A8M9PLJ6-1|A0A8M9PLJ6_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC100538142 PE=4 SV=3 CANONICAL=A0A8M9PLJ6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ6/entry#A0A8M9PLJ6-1", "sequence": { "sequence": "MEIKKEPYRIKVEATKKQTGPVKVNEVRRNHFKNPRNITKENKNADASQTVHRQGQKPGVNGHYNCSACGKIYKHKSGFYRHKRFHTGKGLFTCTQCGKDFPEKGKLDIHMRIHTGERPFTCAQCGQSFIHKPDLTRHMRIHTGERPYTCTQCGKSFIDPSCLKAHSNKHIEEKPFTCAQCGKGFLYQFILNNHLLSHSGVKPFSCHQCDKTFVLEKRLKEHLQVHAAVKPHVCFCGKSFIIMNRLQDHQRIHTGEGPYKCSHCGKSFIYFKSLKTHERNHTGKKP", "length": 286, "header": "tr|A0A8M9PLJ6-1|A0A8M9PLJ6_DANRE Isoform 1 of C2H2-type domain-containing protein OS=Danio rerio OX=7955 GN=LOC100538142 PE=4 SV=3 CANONICAL=A0A8M9PLJ6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100538142", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100538142", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ6" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ6" } ], "pmid": "" }, { "name": "DNA-binding transcription activator activity, RNA polymerase II-specific", "id": "GO:0001228", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001228", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLJ6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PLJ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ6" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 91, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 280, "end_pos": 282 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PLJ9-1", "uniprot_ac": "A0A8M9PLJ9", "uniprot_id": "A0A8M9PLJ9_DANRE", "mass": { "chemical_mass": 45058.0, "monoisotopic_mass": 45058.0 }, "refseq": { "ac": "XP_021322070", "name": "zona pellucida-like domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322070" }, "gene_names": [ { "name": "zpld1b", "type": "recommended", "evidence": [ { "id": "A0A8M9PLJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ9" } ] }, { "name": "zpld1b", "type": "synonym", "evidence": [ { "id": "XP_021322070", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322070" } ] } ], "protein_names": [ { "name": "Zona pellucida-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8M9PLJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ9/entry#names_and_taxonomy" } ] }, { "name": "zona pellucida-like domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_021322070", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322070" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322070" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zpld1b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-121214-104", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-104", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PLJ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PLJ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100333394", "url": "https://www.ncbi.nlm.nih.gov/gene/100333394", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100333394", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333394", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PLJ9", "url": "https://www.orthodb.org/?gene=A0A8M9PLJ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14002:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14002:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00100", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00100", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322070", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322070", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-121214-104", "url": "https://zfin.org/ZDB-GENE-121214-104", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEWMCVILVLFKGIHLAFSQFNGFNCDPNYHSRFPGERDISIYCGVQTITLKINLCPVLYSGYTDVDLALNSRHGEPQCRGFINNNTFPTAVLFSISLSSLEACGNTLQVSTTQGINAYGNISMVQMGNISGYIDTPDPPTVISYLPGLVYKFSCSYPLEYLLNNSQLASSSAAITVKDNNGTFLSTLSLVLYNDSTFNQLISIPVSGLSLKTRVFAAVKATNLDRRWNVLMDHCYATPSGNPKDEIRYDLFFGCYKDPQTTVFENGKSQMGRFAFEVFRFVKHKNQKMSTVFLHCITKLCRADDCAILMPICGKRRRRDSEAEHTVSGSSSGDAVITAGPIITRSDESPTNNSQLVSSSSQPLNAVTSALISGVVVLGVMSLGLFILSLRLLRKPSPSNLTGLWNPSSR", "length": 410, "header": "tr|A0A8M9PLJ9-1|A0A8M9PLJ9_DANRE Isoform 1 of Zona pellucida-like domain-containing protein 1 OS=Danio rerio OX=7955 GN=zpld1b PE=4 SV=1 CANONICAL=A0A8M9PLJ9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ9/entry#A0A8M9PLJ9-1", "sequence": { "sequence": "MEWMCVILVLFKGIHLAFSQFNGFNCDPNYHSRFPGERDISIYCGVQTITLKINLCPVLYSGYTDVDLALNSRHGEPQCRGFINNNTFPTAVLFSISLSSLEACGNTLQVSTTQGINAYGNISMVQMGNISGYIDTPDPPTVISYLPGLVYKFSCSYPLEYLLNNSQLASSSAAITVKDNNGTFLSTLSLVLYNDSTFNQLISIPVSGLSLKTRVFAAVKATNLDRRWNVLMDHCYATPSGNPKDEIRYDLFFGCYKDPQTTVFENGKSQMGRFAFEVFRFVKHKNQKMSTVFLHCITKLCRADDCAILMPICGKRRRRDSEAEHTVSGSSSGDAVITAGPIITRSDESPTNNSQLVSSSSQPLNAVTSALISGVVVLGVMSLGLFILSLRLLRKPSPSNLTGLWNPSSR", "length": 410, "header": "tr|A0A8M9PLJ9-1|A0A8M9PLJ9_DANRE Isoform 1 of Zona pellucida-like domain-containing protein 1 OS=Danio rerio OX=7955 GN=zpld1b PE=4 SV=1 CANONICAL=A0A8M9PLJ9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100333394", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333394", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AAZ2-1", "protein_name": "Zona pellucida-like domain-containing protein 1", "gene_name": "Zpld1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQIWLLLLLAIRVFPGSAQFNSYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVGASGNATSVQIGNISGYIDTPDPPTVISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYREQLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDETRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCLTKLCRADDCPLLMPICGNRKRRDAQSWTTWAPQSTSGNAVLSAGPIITRSDETPTNNSQLGSLSVPPFQLNAVTSSLISGMVILGVMCFSLLLCSLALLHRKGSTSLVLNGVRNPVFE", "length": 415 }, "evidence": [ { "id": "HGNC:27022", "url": "https://alliancegenome.org/gene/HGNC:27022#orthology", "database": "AGR" }, { "id": "MGI:2443415", "url": "https://alliancegenome.org/gene/MGI:2443415#orthology", "database": "AGR" }, { "id": "RGD:1308138", "url": "https://alliancegenome.org/gene/RGD:1308138#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121214-104", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-104#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BGZ8-1", "protein_name": "Zona pellucida-like domain-containing protein 1", "gene_name": "Zpld1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MERVWLLFLLAIRVSPGSAQFNSYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVGASGNATTVQIGNISGYIDTPDPPAVISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYREQLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDDTRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCLTKLCRADDCPLLMPICGNRKRRDAQSWTTWAPQSTSGNAVLSAGPIITRSDETPTNNSQLGSLSVPPFQLNAVTSSLISGMVILGVLCFSLLLCSLALLHRKGSTSLVLNGVRNPVFE", "length": 415 }, "evidence": [ { "id": "HGNC:27022", "url": "https://alliancegenome.org/gene/HGNC:27022#orthology", "database": "AGR" }, { "id": "MGI:2443415", "url": "https://alliancegenome.org/gene/MGI:2443415#orthology", "database": "AGR" }, { "id": "RGD:1308138", "url": "https://alliancegenome.org/gene/RGD:1308138#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121214-104", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-104#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TCW7-1", "protein_name": "Zona pellucida-like domain-containing protein 1", "gene_name": "ZPLD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQIWLLLLLTIRVLPGSAQFNGYNCDANLHSRFPAERDISVYCGVQAITMKINFCTVLFSGYSETDLALNGRHGDSHCRGFINNNTFPAVVIFIINLSTLEGCGNNLVVSTIPGVSAYGNATSVQVGNISGYIDTPDPPTIISYLPGLLYKFSCSYPLEYLVNNTQLASSSAAISVRENNGTFVSTLNLLLYNDSTYNQQLIIPSIGLPLKTKVFAAVQATNLDGRWNVLMDYCYTTPSGNPNDDIRYDLFLSCDKDPQTTVIENGRSQRGRFSFEVFRFVKHKNQKMSTVFLHCVTKLCRADDCPFLMPICSHRERRDAGRRTTWSPQSSSGSAVLSAGPIITRSDETPTNNSQLGSPSMPPFQLNAITSALISGMVILGVTSFSLLLCSLALLHRKGPTSLVLNGIRNPVFD", "length": 415 }, "evidence": [ { "id": "HGNC:27022", "url": "https://alliancegenome.org/gene/HGNC:27022#orthology", "database": "AGR" }, { "id": "MGI:2443415", "url": "https://alliancegenome.org/gene/MGI:2443415#orthology", "database": "AGR" }, { "id": "RGD:1308138", "url": "https://alliancegenome.org/gene/RGD:1308138#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121214-104", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-104#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ9" } ], "pmid": "" }, { "name": "cell surface", "id": "GO:0009986", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009986", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLJ9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 181, "end_pos": 183, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 352, "end_pos": 354, "annotation": "n_glycosylation_sequon" }, { "start_pos": 400, "end_pos": 402, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PLJ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLJ9" }, { "id": "PS51034", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51034" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ZP", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 320, "start_aa": "Tyr", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 129, "end_pos": 131 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 181, "end_pos": 183 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 352, "end_pos": 354 }, { "start_pos": 400, "end_pos": 402 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PLL5-1", "uniprot_ac": "A0A8M9PLL5", "uniprot_id": "A0A8M9PLL5_DANRE", "mass": { "chemical_mass": 148652.0, "monoisotopic_mass": 148652.0 }, "refseq": { "ac": "XP_021327923", "name": "ankyrin repeat and fibronectin type-III domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327923" }, "gene_names": [ { "name": "LOC101885714", "type": "recommended", "evidence": [ { "id": "A0A8M9PLL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLL5" } ] }, { "name": "LOC101885714", "type": "synonym", "evidence": [ { "id": "XP_021327923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327923" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and fibronectin type-III domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "A0A8M9PLL5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLL5/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and fibronectin type-III domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_021327923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327923" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021327923.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021327923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327923" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLL5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLL5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101885714", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLL5", "locus": {} } ], "crossref": [ { "id": "A0A8M9PLL5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PLL5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101885714", "url": "https://www.ncbi.nlm.nih.gov/gene/101885714", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039269", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039269", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885714", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885714", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PLL5", "url": "https://www.orthodb.org/?gene=A0A8M9PLL5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21437", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21437", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21437:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21437:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00041", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00041", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021327923", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327923", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLL5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAPPQRRRSFGPVSPKYIYRSLSLKLRGGASQCEAEHTDWRRRLSKGQADFWSLWDALENEDTLGVQHLLSREQATDTHTHRRVNRVTELGLVPLDVALLTQNASLLKVLLKAGAKHNPTLISASDWSLKLDELVSLAEQKLEEWRAELEVREKAELQVRVRAELQTHTDAQKNVEQWRRRRELYQNMRERFNRTTPPPPPAGAALQVTGDSSVCVRVSEPLGHTHGLISRYRVEWSSASSFHPLCGSAFISDIRSPEFSITGLQTGVQYYVRVSAYNVRGWSPAQSSSPVCVAPSSWSSCGGVTVRSRNQAAAVRSIIQQIRETRPNENTGSGKRVSRGLKQLFHSSSRSVCRLQRGVYLSCVLYQKDGVVLCSDDQLPLVEVQSCSTSITQDLLWLAKLSCAWPQVSVLQQSSSSSLSSSSSLLQNRLSFLRAVAQLQAWLGCVDLGQVYFEPLKDRQGAVLLVTLREVTTPLTLTDPALHWTPISTLEQNQSRTPLLPEPSAVELLHTHLREMLSYHRRSLQRAAPGLYVCVLKLCSSVDQLRVLVPHRLPNMLCHSRVRNCPHVTREEWAWLQRHGVGGACDGPEGEDQCVIDSSGVEHFVKDLRSAVTQLFTKLNVPLHRACEYRVYTQELVRAGDQLSLIILLPPSEDCRSDRWRSDAQRFTLPLHIFELVHLCVYEQQLLSLYCEAWLRLELDVCVWQQTLREALDSRETADAEERLTHTTQLTQSLSSLWRESRWLMDVIQVLRSKHCEGAVPLGRVMTSRPPITPASAEDSPPCLHTAAQDKDAAGHFCSDLFYGSKVTTSVNITNEVTNGVKEKLTDKCVDRATDRVADEVTDKITDKVPDEVTDNITNEVTDNITDGVTDSVTDKITDKVANKITDGVTDKITNEVTDKITDKDANKITDEVTDGVTDKITDEVTDGVTDKITVEVTDKITVEVTDRVTDKITDEVTDRVTDKITDEVTDRVTDKITDEVANKIIDGVTDKVTGEVAGKITDKVTDSVTDKITDRVANKITDRVTDKITDETTDKITDVVTDGVTDKITVEVTDGVTDKITDEATDKITDEVTDRVTDKITDEVANKITDRVTDSVTDKITDKVTDKITDKVTDKITDKVTDSVTDKITDKDAKKITDGVTDKITDETTDKITDEVANKIIDGVTDSVTDKITDGVTDKITDEVTDKITDGVTDKITDGVADMIIDGVTDRVANKFTDSMTDGVRVGVLHSQWSSSACPHAIGLQHGHWCPELCQSPSADPEQQTDRSPDLLSDMMELLQRLDLLGDGLLELLDPEQALQEQESQSGAAADGAVQLSASRGRPVRSVVEWVTSAHQQP", "length": 1339, "header": "tr|A0A8M9PLL5-1|A0A8M9PLL5_DANRE Isoform 1 of Ankyrin repeat and fibronectin type-III domain-containing protein 1 OS=Danio rerio OX=7955 GN=LOC101885714 PE=4 SV=2 CANONICAL=A0A8M9PLL5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLL5/entry#A0A8M9PLL5-1", "sequence": { "sequence": "MAPPQRRRSFGPVSPKYIYRSLSLKLRGGASQCEAEHTDWRRRLSKGQADFWSLWDALENEDTLGVQHLLSREQATDTHTHRRVNRVTELGLVPLDVALLTQNASLLKVLLKAGAKHNPTLISASDWSLKLDELVSLAEQKLEEWRAELEVREKAELQVRVRAELQTHTDAQKNVEQWRRRRELYQNMRERFNRTTPPPPPAGAALQVTGDSSVCVRVSEPLGHTHGLISRYRVEWSSASSFHPLCGSAFISDIRSPEFSITGLQTGVQYYVRVSAYNVRGWSPAQSSSPVCVAPSSWSSCGGVTVRSRNQAAAVRSIIQQIRETRPNENTGSGKRVSRGLKQLFHSSSRSVCRLQRGVYLSCVLYQKDGVVLCSDDQLPLVEVQSCSTSITQDLLWLAKLSCAWPQVSVLQQSSSSSLSSSSSLLQNRLSFLRAVAQLQAWLGCVDLGQVYFEPLKDRQGAVLLVTLREVTTPLTLTDPALHWTPISTLEQNQSRTPLLPEPSAVELLHTHLREMLSYHRRSLQRAAPGLYVCVLKLCSSVDQLRVLVPHRLPNMLCHSRVRNCPHVTREEWAWLQRHGVGGACDGPEGEDQCVIDSSGVEHFVKDLRSAVTQLFTKLNVPLHRACEYRVYTQELVRAGDQLSLIILLPPSEDCRSDRWRSDAQRFTLPLHIFELVHLCVYEQQLLSLYCEAWLRLELDVCVWQQTLREALDSRETADAEERLTHTTQLTQSLSSLWRESRWLMDVIQVLRSKHCEGAVPLGRVMTSRPPITPASAEDSPPCLHTAAQDKDAAGHFCSDLFYGSKVTTSVNITNEVTNGVKEKLTDKCVDRATDRVADEVTDKITDKVPDEVTDNITNEVTDNITDGVTDSVTDKITDKVANKITDGVTDKITNEVTDKITDKDANKITDEVTDGVTDKITDEVTDGVTDKITVEVTDKITVEVTDRVTDKITDEVTDRVTDKITDEVTDRVTDKITDEVANKIIDGVTDKVTGEVAGKITDKVTDSVTDKITDRVANKITDRVTDKITDETTDKITDVVTDGVTDKITVEVTDGVTDKITDEATDKITDEVTDRVTDKITDEVANKITDRVTDSVTDKITDKVTDKITDKVTDKITDKVTDSVTDKITDKDAKKITDGVTDKITDETTDKITDEVANKIIDGVTDSVTDKITDGVTDKITDEVTDKITDGVTDKITDGVADMIIDGVTDRVANKFTDSMTDGVRVGVLHSQWSSSACPHAIGLQHGHWCPELCQSPSADPEQQTDRSPDLLSDMMELLQRLDLLGDGLLELLDPEQALQEQESQSGAAADGAVQLSASRGRPVRSVVEWVTSAHQQP", "length": 1339, "header": "tr|A0A8M9PLL5-1|A0A8M9PLL5_DANRE Isoform 1 of Ankyrin repeat and fibronectin type-III domain-containing protein 1 OS=Danio rerio OX=7955 GN=LOC101885714 PE=4 SV=2 CANONICAL=A0A8M9PLL5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 773, "start_aa": "Thr", "end_pos": 773, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr773", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101885714", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885714", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLL5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLL5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 103, "end_pos": 105, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 493, "end_pos": 495, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 856, "end_pos": 858, "annotation": "n_glycosylation_sequon" }, { "start_pos": 864, "end_pos": 866, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021322095.1. 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"phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PLN2-1", "uniprot_ac": "A0A8M9PLN2", "uniprot_id": "A0A8M9PLN2_DANRE", "mass": { "chemical_mass": 58342.0, "monoisotopic_mass": 58342.0 }, "refseq": { "ac": "XP_005163509", "name": "ankyrin repeat domain-containing protein 33B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163509" }, "gene_names": [ { "name": "ankrd33bb", "type": "recommended", "evidence": [ { "id": "A0A8M9PLN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLN2" } ] }, { "name": "ankrd33bb", "type": "synonym", "evidence": [ { "id": "XP_005163509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163509" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 33B", "type": "synonym", "evidence": [ { "id": "A0A8M9PLN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLN2/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 33B", "type": "synonym", "evidence": [ { "id": "XP_005163509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163509" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005163509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163509" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLN2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLN2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ankrd33bb", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLN2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-531", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-531", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "557905", "url": "https://www.ncbi.nlm.nih.gov/gene/557905", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:557905", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557905", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PLN2", "url": "https://www.orthodb.org/?gene=A0A8M9PLN2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173:SF91", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173:SF91", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005163509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005163509", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLN2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-531", "url": "https://zfin.org/ZDB-GENE-070912-531", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVLITENGVAGGVVLVKVHKHDTEDNRARGWTNEESSIQSSTVVEPNEDSYYADDDEDHHFYDDDDDDDDVYQEFEELDFSKLPDSRSMASDDSFYPPDDSLSFEKCPSPESPEPVSFFKACCSNNVIIVKIMIRQGVTEAEVREVDKNNRTGLIVACYQGYVDVVIALSQCPHVDVNWQDNEGNTALINAAQAGHSMITHYLLNYFPGIDTERRNCHGFTALMKAAMQGRAECVRSLMMTGGDIEARDFGRKLTPQEWALFTGRYETAKLISRLMDKPCAEQFCDSYHMGWPMLSEMVARSKEPKSCWRKFSECICNMFNISMKTNPVDEGVMDYTVRMTTALASPLIATACHTVCPGSPPCVGKRRPAVQDILRRQRLAELKNLGPDRLNNYKRLFQNSRVLLVPKKQERRASLQPQLLHSVAMASTVALRRNSLLPLHMMRRSSVRPGMVVPKVMLCKAPPPIHMPERPPRRSSNDSAQLQIPKWKYKALKEEKKKAEQMERLRLPIGRKK", "length": 514, "header": "tr|A0A8M9PLN2-1|A0A8M9PLN2_DANRE Isoform 1 of Ankyrin repeat domain-containing protein 33B OS=Danio rerio OX=7955 GN=ankrd33bb PE=4 SV=1 CANONICAL=A0A8M9PLN2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLN2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLN2/entry#A0A8M9PLN2-1", "sequence": { "sequence": "MVLITENGVAGGVVLVKVHKHDTEDNRARGWTNEESSIQSSTVVEPNEDSYYADDDEDHHFYDDDDDDDDVYQEFEELDFSKLPDSRSMASDDSFYPPDDSLSFEKCPSPESPEPVSFFKACCSNNVIIVKIMIRQGVTEAEVREVDKNNRTGLIVACYQGYVDVVIALSQCPHVDVNWQDNEGNTALINAAQAGHSMITHYLLNYFPGIDTERRNCHGFTALMKAAMQGRAECVRSLMMTGGDIEARDFGRKLTPQEWALFTGRYETAKLISRLMDKPCAEQFCDSYHMGWPMLSEMVARSKEPKSCWRKFSECICNMFNISMKTNPVDEGVMDYTVRMTTALASPLIATACHTVCPGSPPCVGKRRPAVQDILRRQRLAELKNLGPDRLNNYKRLFQNSRVLLVPKKQERRASLQPQLLHSVAMASTVALRRNSLLPLHMMRRSSVRPGMVVPKVMLCKAPPPIHMPERPPRRSSNDSAQLQIPKWKYKALKEEKKKAEQMERLRLPIGRKK", "length": 514, "header": "tr|A0A8M9PLN2-1|A0A8M9PLN2_DANRE Isoform 1 of Ankyrin repeat domain-containing protein 33B OS=Danio rerio OX=7955 GN=ankrd33bb PE=4 SV=1 CANONICAL=A0A8M9PLN2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:557905", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557905", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7UVK1-1", "protein_name": "Ankyrin repeat domain-containing protein 33B isoform X1", "gene_name": "ankrd33ba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLITDSRDGGGSSPGKVKPLKHAKGAQICPTIVEESPDHTGNDDYDEFLGTCEFDGNNEDFEELDDFSELPDTRSIASDDSFYPPDDDFADSERTPSPESPAPLSFFQACCGNNALIVKLMIRQGVTEEDVRETDKNKRTGLIVACYQGYVDVVMALSQCPHLDVNWSDNEGNTALITASQAGHITICNYLLNYFPGLDIEKRNCHGFSALMKAAMQGRVECVKALMMAGADLEARDNGRKFTAREWAIFTSRHETVLTIMRLMHQPCADQFCDSYRPEWPLLPALVAKAQAPKGCIQKISETLRDFFDISNVTEASEDGVLDHMVRMTTALGSPFIATSCRTVCPGSPPCVGKRRYAVQEILKKRRIEQLKILGPERIENYKRLFQNSRVLLVPKPKDRRASLQPNAQAEDSSTLTIRRTSLLPLHLLRRSSVRPGLVVPKVRITKAPTPTYVPERVRRKSSCVEEQFLQIPKWRYKELKEERKKAEEAERKRLEAITKRQLTTGKRK", "length": 510 }, "evidence": [ { "id": "RGD:1564227", "url": "https://alliancegenome.org/gene/RGD:1564227#orthology", "database": "AGR" }, { "id": "MGI:1917904", "url": "https://alliancegenome.org/gene/MGI:1917904#orthology", "database": "AGR" }, { "id": "HGNC:35240", "url": "https://alliancegenome.org/gene/HGNC:35240#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCL7-1", "protein_name": "Ankyrin repeat domain-containing protein 33B", "gene_name": "ANKRD33B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT", "length": 494 }, "evidence": [ { "id": "RGD:1564227", "url": "https://alliancegenome.org/gene/RGD:1564227#orthology", "database": "AGR" }, { "id": "MGI:1917904", "url": "https://alliancegenome.org/gene/MGI:1917904#orthology", "database": "AGR" }, { "id": "HGNC:35240", "url": "https://alliancegenome.org/gene/HGNC:35240#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-531", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-531#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZTU7-1", "protein_name": "Ankyrin repeat domain 33B", "gene_name": "Ankrd33b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLLAGPGPEGGGTRCLSPQSPTPPRSVQTGDDPADYEEYEDFSSLPDTRSIASDDSFYPPGGEEECGSVCAESVPEGVPESATLLRAACANDVGLLRALVRRGPSSEEARETDRNGRTGLIIACYHGFVDTVVALAECPHIDVNWQDSEGNTALITAAQAGHATITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMLAGADVQARDPRRGLSPQEWAAYTGRAEAVRVMQRLMERPCPEQFGDKYKLELPLPAETILKKAGSKNCLQRFTAFLRSTLTSRSGQSLEDGGVLDHMVRMTTSLYSPAVAVVCQTVCPENPPCVGKRRLAVQEILAARGNLDAQAQDSNNVELQSQILETPRASSRSPQSLGSGSTPAPVTRKASLLPLQLLRRSSVRPGVVVPRVRISKAPAPTFQPERAASKGNTKDSIYLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRAPRWRKRT", "length": 481 }, "evidence": [ { "id": "RGD:1564227", "url": "https://alliancegenome.org/gene/RGD:1564227#orthology", "database": "AGR" }, { "id": "MGI:1917904", "url": "https://alliancegenome.org/gene/MGI:1917904#orthology", "database": "AGR" }, { "id": "HGNC:35240", "url": "https://alliancegenome.org/gene/HGNC:35240#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-531", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-531#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3U0L2-1", "protein_name": "Ankyrin repeat domain-containing protein 33B", "gene_name": "Ankrd33b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLLAGPGPEGGGTRCLSPQSPTPPRSEQTGEDPADYEEYEDFSSLPDTRSIASDDSFYPPGGEEEYGSVSAESVPEGVPEAATLLRAACANDVGLLRALVRRGPSSEEVRETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADVQARDPRRGLSPQEWAAYTGRAEAVRVIQRLMERPCPEQFGDKYKLELPLPAEAVLKKSGSKNCLQRFTAFLRSTLTSRSSGQSLEDGGVLDHMVRMTTSLYSPAVAVVCQTVCPENPPCVGKRRLAVQEILAARGNLNAQAQDSNKVECSEPQSQILETPRASSRSPKSPAASRSTPAPVTRKASLLPLQLLRRSSVRPGVVVPRVRISKAPAPTFQPERAASKGNTKDSIYLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKEKRAPRWRKRT", "length": 486 }, "evidence": [ { "id": "RGD:1564227", "url": "https://alliancegenome.org/gene/RGD:1564227#orthology", "database": "AGR" }, { "id": "MGI:1917904", "url": "https://alliancegenome.org/gene/MGI:1917904#orthology", "database": "AGR" }, { "id": "HGNC:35240", "url": "https://alliancegenome.org/gene/HGNC:35240#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-531", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-531#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 321, "end_pos": 323, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 150, "end_pos": 152 }, { "start_pos": 321, "end_pos": 323 }, { "start_pos": 478, "end_pos": 480 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PLQ1-1", "uniprot_ac": "A0A8M9PLQ1", "uniprot_id": "A0A8M9PLQ1_DANRE", "mass": { "chemical_mass": 218466.0, "monoisotopic_mass": 218466.0 }, "refseq": { "ac": "XP_021323191", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323191" }, "gene_names": [ { "name": "LOC101885155", "type": "recommended", "evidence": [ { "id": "A0A8M9PLQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLQ1" } ] }, { "name": "LOC101885155", "type": "synonym", "evidence": [ { "id": "XP_021323191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323191" } ] } ], "protein_names": [ { "name": "Integrase catalytic domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PLQ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLQ1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021323191", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323191" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. 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"length": 1936, "header": "tr|A0A8M9PLQ1-1|A0A8M9PLQ1_DANRE Isoform 1 of Integrase catalytic domain-containing protein OS=Danio rerio OX=7955 GN=LOC101885155 PE=4 SV=1 CANONICAL=A0A8M9PLQ1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 184, "start_aa": "Thr", "end_pos": 184, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr184", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101885155", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885155", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLQ1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLQ1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLQ1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1008, "end_pos": 1010, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1218, "end_pos": 1220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1327, "end_pos": 1329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1459, "end_pos": 1461, "annotation": 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"https://www.uniprot.org/uniprotkb/A0A8M9PLQ1" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 1619, "end_pos": 1812, "start_aa": "Leu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 184 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1008, "end_pos": 1010 }, { "start_pos": 1218, "end_pos": 1220 }, { "start_pos": 1327, "end_pos": 1329 }, { "start_pos": 1459, "end_pos": 1461 }, { "start_pos": 1637, "end_pos": 1639 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 22, "end_pos": 24 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 260, "end_pos": 262 }, { "start_pos": 578, "end_pos": 580 }, { "start_pos": 613, "end_pos": 615 }, { "start_pos": 850, "end_pos": 852 }, { "start_pos": 962, "end_pos": 964 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PLT8-1", "uniprot_ac": "A0A8M9PLT8", "uniprot_id": "A0A8M9PLT8_DANRE", "mass": { "chemical_mass": 114369.0, "monoisotopic_mass": 114369.0 }, "refseq": {}, "gene_names": [ { "name": "nlrc8", "type": "recommended", "evidence": [ { "id": "A0A8M9PLT8", "database": 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"resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050854", "name": "neutrophilic urticaria", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle-Wells syndrome", "description": "An intermediate form of cryopyrin-associated periodic syndrome (CAPS) and is characterized by recurrent fever (with malaise and chills), recurrent urticaria-like skin rash, sensorineural deafness, general signs of inflammation (eye redness, headaches, arthralgia/myalgia) and potentially life-threatening secondary amyloidosis (AA type)." }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle-Wells syndrome", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "neutrophilic urticaria", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "MWS", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle Wells syndrome", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "urticaria, deafness and amyloidosis", "description": "" }, { "id": "MIM:191900", "resource": "MIM", "url": "https://www.omim.org/entry/191900", "name": "Muckle-Wells syndrome", "description": "Muckle-Wells syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050854", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050854" } ] }, { "disease_id": "DOID:0080208", "recommended_name": { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol." }, "synonyms": [ { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "nonalcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "non-alcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "NAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-related steatotic liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MASLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic-associated fatty liver disease", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "NAFLD2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "fatty liver disease, nonalcoholic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "liver disease, alcoholic, susceptibility to, 1", "description": "" }, { "id": "MIM:613282", "resource": "MIM", "url": "https://www.omim.org/entry/613282", "name": "Non-alcoholic fatty liver disease 1", "description": "Non-alcoholic fatty liver disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ] }, { "disease_id": "DOID:0080270", "recommended_name": { "id": "DOID:0080270", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080270", "name": "autosomal dominant nonsyndromic deafness 34", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q44." }, "synonyms": [ { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "hearing loss, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "DFNA34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "autosomal dominant nonsyndromic deafness 34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "deafness, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MIM:617772", "resource": "MIM", "url": "https://www.omim.org/entry/617772", "name": "Deafness, autosomal dominant, 34, with or without inflammation", "description": "Deafness, autosomal dominant, 34, with or without inflammation" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080270" } ] }, { "disease_id": "DOID:0090029", "recommended_name": { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "CINCA Syndrome", "description": "An autoimmune disease characterized by neonatal onset of cutaneous symptoms, chronic meningitis, and joint manifestations with recurrent fever and inflammation that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q." }, "synonyms": [ { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "IOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "NOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic infantile neurological cutaneous articular syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "Chronic Infantile Neurological, Cutaneous, and Articular (CINCA) syndrome is characterized by skin rash, joint involvement, chronic meningitis with granulocytes and, in some cases, sensorineural hearing loss and ocular signs." }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA/NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Neonatal-Onset Multisystem Inflammatory Disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic infantile neurological cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal onset multisystem inflammatory disease", "description": "" }, { "id": "MIM:607115", "resource": "MIM", "url": "https://www.omim.org/entry/607115", "name": "Chronic infantile neurologic cutaneous and articular syndrome", "description": "Chronic infantile neurologic cutaneous and articular syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090029", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090029" } ] }, { "disease_id": "DOID:0090062", "recommended_name": { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "familial cold autoinflammatory syndrome 1", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP gene on chromosome 1q44." }, "synonyms": [ { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "FCAS1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "Any familial cold autoinflammatory syndrome in which the cause of the disease is a mutation in the NLRP3 gene." }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "NLRP3 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP3", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome type 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold inflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "FCAS1", "description": "" }, { "id": "MIM:120100", "resource": "MIM", "url": "https://www.omim.org/entry/120100", "name": "Familial cold autoinflammatory syndrome 1", "description": "Familial cold autoinflammatory syndrome 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090062", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090062" } ] }, { "disease_id": "DOID:0090063", "recommended_name": { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "familial cold autoinflammatory syndrome 2", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP12 gene on chromosome 19q13." }, "synonyms": [ { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "An autoinflammatory disease caused by mutations in the NLRP12 gene. It is characterized by periodic fevers beginning in the first year of life that are triggered by cold exposure. Episodes occur more than once per month." }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NALP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NAPS12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome type 2", "description": "" }, { "id": "MIM:611762", "resource": "MIM", "url": "https://www.omim.org/entry/611762", "name": "Familial cold autoinflammatory syndrome 2", "description": "Familial cold autoinflammatory syndrome 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090063" } ] }, { "disease_id": "DOID:12351", "recommended_name": { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "alcoholic hepatitis", "description": "" }, "synonyms": [ { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic hepatitis", "description": "" }, { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic liver disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12351" } ] }, { "disease_id": "DOID:1555", "recommended_name": { "id": "DOID:1555", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1555", "name": "urticaria", "description": "A skin disease characterized by skin rash notable for pale red, raised and itchy bumps, located_in the upper dermis." }, "synonyms": [], "unlinked_id_list": [ "DOID:0060220" ], "evidence": [ { "id": "1555", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1555" } ] }, { "disease_id": "DOID:3590", "recommended_name": { "id": "DOID:3590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3590", "name": "gestational trophoblastic neoplasm", "description": "" }, "synonyms": [ { "id": "DOID:3590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3590", "name": "gestational trophoblastic neoplasia", "description": "" }, { "id": "DOID:3590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3590", "name": "hydatidiform mole", "description": "" }, { "id": "DOID:3590", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3590", "name": "molar pregnancy", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "hydatidiform mole, recurrent, 1", "description": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the NLRP7 gene." }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "NLRP7 complete hydatidiform mole", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "complete hydatidiform mole caused by mutation in NLRP7", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "hydatidiform Mole, recurrent, type 1", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "hydatidiform mole, recurrent, 1", "description": "" }, { "id": "MONDO:0009273", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009273", "name": "HYDM1", "description": "" }, { "id": "MIM:231090", "resource": "MIM", "url": "https://www.omim.org/entry/231090", "name": "Hydatidiform mole, recurrent, 1", "description": "Hydatidiform mole, recurrent, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "3590", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3590" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:9452", "recommended_name": { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes." }, "synonyms": [ { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Fatty change of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Steatosis of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "alcoholic fatty liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic lipidosis", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "SLD", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "fatty liver disease", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "fatal neonatal hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLT8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nlrc8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLT8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PLT8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PLT8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00116", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00116", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "795668", "url": "https://www.ncbi.nlm.nih.gov/gene/795668", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:795668", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795668", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LTWCSIT", "url": "https://omabrowser.org/oma/group/LTWCSIT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PLT8", "url": "https://www.orthodb.org/?gene=A0A8M9PLT8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322155", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322155", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLT8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HDP8", "url": "https://www.uniprot.org/uniprotkb/A0AC58HDP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HDP8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HDP8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HDS7", "url": "https://www.uniprot.org/uniprotkb/A0AC58HDS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HDS7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HDS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-363", "url": "https://zfin.org/ZDB-GENE-070912-363", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGSMNHPKHFKSGETQNDLGSAHQKRSDPEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQKRSDPEPSCVSMKSDWSMDPPMQFKSKDTPPDLSSVHQERSEPEPSCMSMNSDLPLDPPIRYKSGETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQSLWSKTKFMFKTVALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLKLKRRSIKNNKTVEYIKKKIRTIDSPEKSINLFHCLNELGDHSLVEEIQQYLKSGGINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAENNKTEKLVIFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTLLSAVLEDPHCKLEKLWLSYCGVTDEGCAALVSALRSNPEHLRELNLSGNNLGDSVTLLSAVLEDPHCKLEKLRLYYCGLTDEGCAALASALRSNPEHLRDLDLSWNKLGDSVTLLSAVLEDPRCKLEKLELYNCGLTDEGCAALASALRSNPEHLRDLNLSGNKLGDSVTLLSAVLEDPRCKLEKLWLSDCGLTDEGCAALASALRSNPEHLTELDLSWNNLSKSTVRLFSDLKDNPHNKLKTLHI", "length": 1017, "header": "tr|A0A8M9PLT8-1|A0A8M9PLT8_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=nlrc8 PE=4 SV=1 CANONICAL=A0A8M9PLT8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLT8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLT8/entry#A0A8M9PLT8-1", "sequence": { "sequence": "MGSMNHPKHFKSGETQNDLGSAHQKRSDPEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQKRSDPEPSCVSMKSDWSMDPPMQFKSKDTPPDLSSVHQERSEPEPSCMSMNSDLPLDPPIRYKSGETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQSLWSKTKFMFKTVALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLKLKRRSIKNNKTVEYIKKKIRTIDSPEKSINLFHCLNELGDHSLVEEIQQYLKSGGINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAENNKTEKLVIFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTLLSAVLEDPHCKLEKLWLSYCGVTDEGCAALVSALRSNPEHLRELNLSGNNLGDSVTLLSAVLEDPHCKLEKLRLYYCGLTDEGCAALASALRSNPEHLRDLDLSWNKLGDSVTLLSAVLEDPRCKLEKLELYNCGLTDEGCAALASALRSNPEHLRDLNLSGNKLGDSVTLLSAVLEDPRCKLEKLWLSDCGLTDEGCAALASALRSNPEHLTELDLSWNNLSKSTVRLFSDLKDNPHNKLKTLHI", "length": 1017, "header": "tr|A0A8M9PLT8-1|A0A8M9PLT8_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=nlrc8 PE=4 SV=1 CANONICAL=A0A8M9PLT8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HDP8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLT8/entry#A0AC58HDP8-1", "sequence": { "sequence": "MGSMNHPKHFKSGETQNDLGSAHQKRSDPEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQKRSDPEPSCVSMKSDWSMDPPMQFKSKDTPPDLSSVHQERSEPEPSCMSMNSDLPLDPPIRYKSGETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQSLWSKTKFMFKTVALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLKLKRRSIKNNKTVEYIKKKIRTIDSPEKSINLFHCLNELGDHSLVEEIQQYLKSGGINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAENNKTEKLVIFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTLLSAVLEDPHCKLEKLWLYYCGLTDEGCAALASALRSNPEHLRDLDLSWNKLGDSVTLLSAVLEDPRCKLEKLELYNCGLTDEGCAALASALRSNPEHLRDLNLSGNKLGDSVTLLSAVLEDPRCKLEKLWLSDCGLTDEGCAALASALRSNPEHLTELDLSWNNLSKSTVRLFSDLKDNPHNKLKTLHI", "length": 960, "header": "tr|A0AC58HDP8-1|A0AC58HDP8_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X2 OS=Danio rerio OX=7955 GN=nlrc8 PE=4 SV=1 CANONICAL=A0A8M9PLT8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HDS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLT8/entry#A0AC58HDS7-1", "sequence": { "sequence": "MGSMNHPKHFKSGETQNDLGSAHQKRSDPEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQKRSDPEPSCVSMKSDWSMDPPMQFKSKDTPPDLSSVHQERSEPEPSCMSMNSDLPLDPPIRYKSGETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQSLWSKTKFMFKTVALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLKLKRRSIKNNKTVEYIKKKIRTIDSPEKSINLFHCLNELGDHSLVEEIQQYLKSGGINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAENNKTEKLVIFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTLLSAVLEDPHCKLEKLWLSDCGLTDEGCAALASALRSNPEHLTELDLSWNNLSKSTVRLFSDLKDNPHNKLKTLHI", "length": 846, "header": "tr|A0AC58HDS7-1|A0AC58HDS7_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X3 OS=Danio rerio OX=7955 GN=nlrc8 PE=4 SV=1 CANONICAL=A0A8M9PLT8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:795668", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795668", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JW23-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPATAKDALHRLSTYLEELEAGELKKFKLYLGIAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGEDLVRVTPSNGLCSLESQSTCLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGPWCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTSRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFTAMYCALHGREAVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAEDGPPEPPGAQTQSTHSQERNILPDIYSAYLSATICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIANRNLIRLDLSGNSIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSNNSHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVNTCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGISQTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFGMDLNKVTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1PS14-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:dkey-222h21.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNMLQRIKNQHKTSLKNKYERLFEGIEVKETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPENLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGIDVSDASVYSGICTEILKEESVIQQRKVYSFIHLSFQEFLAAFHVFYHHITCSTEASLDSLHDLQKRIINKSTESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKRSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELKLQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITPGLRKYACVLTLDPNTAHTHLVLSEKNRQARNVTDPQPYPDHPDRFKNNEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYSCDTIYTVWHNNKSADIIAPSACTNRVGVYVDVPSGSLSFYSVTDTHTLTLIHTFNTTFTEELYTGFGIYPEASVSLCQI", "length": 892 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RJ47-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "si:ch211-201o1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMSAEKSDDAPATGSSPEDLQAEQHEQKKSDSSTVSHVSMKSGRSITPPLDFRKDEQGNTERAKQERAESSTASHLSMKSDRSITPPLDFISGEQKQTERKSVDDHAVSTSADRVCQRHHRALDVFCQTDNIHICCICVEEEHQGHRKTYTAKLNVPDSQSMLLHIMEKMRSEDFNTFKRELSEDYAGCLGAQSEELSVSEAAENIMRSFGGEAALRLILHFQTKANPLKKITDANKTKLKNKCQNINEGNSSYGKQSLLMEVYTDLYFTEGGSGEINNEHEVLRNEMISQSRTTQEVLYACDEIFKTLPGQRTQVRTVLTMGIAGIGKHVSVQKFILDWAEGKANQDIEIIIHLPFRDLSCREESCSLLQLVHQYSPELREADLQHLKVLFILDGLELCQYPLHFHKNVYCADINEKVPVDALLTNLIKGNLLPSALLWITTRPSTAGRIPPECVHRVTEIRGFSDDQKDSYFRKKISDQTLADEIIRHIKSCQSLYIMCHMPIFCWISATVLENIMREGQSEELPRTLTGMFTHFLLLQVSLKHKKFNGADGDNPKKLSEFDQTFILKLGELAFQQMEKGDLIFREEDLREGGIDVSKVSEYSVCTEFFREELGLYREKLYGFLHVSYQEFLAAIYAHFTCVNDGRNVFLKDESRSSVDLCDVHQTAVEKALQSENGHLDLFLRFLLGLSVDSNFNLLQDLLKDTSCKPRVDTSSTVSFIKEKVKLEQSPERIINLFHCLNQLNDNSLVEEIKAAMKSGTLLGSELDPEQWSALAYVYLTSGEEIEEFDMIKSNQLRLLPVLRICKKARLNCCNLSFASCGLVASALKSVNSPLTELDLSNCKLNIFGMNTLLDGLKSPHSKVKKLRLAGCFFPSETCANLALALKSVNSQVTELDLSYNKITDGVHKFCAGLTSQNCKLQKLVLKRCGLTKASCAHLASVLKSNTHLMELELKGNDLQDSGVELLSTGLMDPQCRLEKLGLSGCMITKVGCNSLASALTSNADCMSELDLTYNHPGDSGVKLLTAKKEDPNCKLEKLHVKKRGECRMKPGLRKYACQLTVDPNTIHPRLIVSNDNRTISETTEHQKYPVHPDRYTLYPQAMCREPLADRSYFEVKCTGGVSIGVAYKTSDRTEDLMGFNNTFPSLMCLNGRIKLWQNNDVIHYELPVFAQSSRVGVYVDQYQGSLSYYSICKDTLIHLHTHHTEFTSPLYIGFLFMPDSSVTLLDDSL", "length": 1231 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AHM3-1", "protein_name": "Uncharacterized protein si:dkey-23k10.3 isoform X1", "gene_name": "si:dkey-23k10.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVFLHTTHLYSGQTEVSGYKSTVLRSFVRPSYILKFERNCYHEFSRIHLLSTLLQWQVNLETLRFSACGITDEACFALAKALTSKLSHLRELDLSENKLGDAGVMVLSAALENNCSDLVSLKMNDCDLTYEGCSHLASALASNPSHLRELDLSKNKLDDVEMLVLAAGLENSSCKLEKLRLVKCGLTDEGFVVLNKALRSNPSHLKELDLSENSLCYLHTMLLSSVLESPYWELKTLKLVNCSFTEEGGAALMSALRSNPSHLRELDLSKNNIGYLTMMVLSSAMEIPYWELEILRLNDCGITDDGFAALGAGLRSNPSYLRELDLSKNKLGEFGVHMLSIALEMPYCQLETLRLVSCDITGNGWIVLVSALRSNPSHLRNLDLSGNNLECFEIKLLSEVLESPYCKLETLKLRNCNLKDEECVSLASALRLKISKLRELDLSENKLGDSGVKAFFAELEGHLSKFDALRFVNCGLTDEGCGVLASVLSSNPSHLKELDLSGNKVEDSGVKMLSDGLEDYCCRLETLKLVGCGLTDEGCASLASALTSNSSHLRVLDLSKNKLSDSGVRLISTGLENPHCKVEILWLVDCDVNDEGCAALASALTFNFSNLRELDLSENNLGDFGVKLLSAGLEDPHCKLEILKLKNCGFTDGGIAALAPVLGSDHSYLKNVDLSGNKFEDFGVQLLSIAFY", "length": 692 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3ANC0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch73-168d20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSRKRRSSSPESSCVSIKSDASMDNPPTLRLGESPAKHRRSSSLGSSCVSMKSDASMDNPPTLRLGESPAKHRRSSSPESSCVSMKSDASMDNPPTLRLGESPAKHSDNQKRSQSNKGQKQLDAIFKDLEETNIDEMRKVLRRFKMLLSPDYSVRDEEEEEGQRQINEAFLKITLHALQKMNQTDLASKLQTKLISVSQQQLKSRLKQRFERFTEGVSNRGNTKLLNDIYTEVYITEGGAGNIDDEHEVRQIETSSSRFPEIPIRCCDIFKSLLGQDKAIRTVLTKGVAGIGKTASVQKFILDWAEGKANQDVHFIFPLPFRDLNLIKEKRMSLMELLCCFCPELKPIDYNNFKTVFIYDGLDEWRLPLDFRNNEILWDMNKVASVDALLTNLLQGNLLPSAVHWITTRPAAACQIPAEFIDRVTEVRGFKDLQRAEYFWKRIKDQNLANKIITHIQSSRSLHIMCRIPVFCWISATVLEKIFGEANSADIPKTLTQMFIHLLIVQTNLKTQKYDRECDVNLEKARKSILSLAKLAFEQLEKGNLIFYEEDLKQCGIDVREASVCSGVCTQIFREEFGLQLQKVFSFVHLSVQEFLAALFKFLSFAEENNKSSMTQFMKNEVDRALQSPNGHLDLFLRFLLGLSLDSNQTLLQGLFTPLDTSHSRDETIEYIKSKIRENPSPERSINLFYCLNELNDHSLVQEVQTYLTSTRSHRLSGVKLSPALWSALVFVLLNSTKDLDEFELRQYDFTEECLLRLLPVVKASRKADLKGGNLTDQICSALASALSSSSCCLRELDLSENRLQLSGIRLFSAGLKSPNCKLEILKLSNCSIREEGCASLVSALLSNPSHLRELNLNSNQPGYSTVKLLSDLLENPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLNGSNIREKDCAAFISSLLSNPFHLRELSLSWNKPGDSGVKLLSDLLKDSRCKLEKLELECCSIIEEGCAALALALVSNPSHLRELNLNNNEPGDLGVNLLSFLLKNPQCKLEKLELEYCCIGAKSCASLASAFVSNPSHLRELNLNWNTPEYPAVKLLSDYLKDPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLEYCCIGEEGCAALVSGLKSNPSHLRELNLNRNEPGNLGAKMLSDLLKDPLFELEKLELDDCSIENNGFADLVSGLKSNPSNIRELNLNSNKFIFSGLNLLCDLLRDQQCKLRKLQLECCNIDEEGCAALALALISNPSHLRELNLNYNNPGGLGVKLLSVLLKNPHCKLEKLELSHCSISENYLAALNSALSSNPAHLRELNLNYNENTRQ", "length": 1388 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQ59-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKIFQNLTAESGKGIRDYVVQIRFCFIMDDTQISRDENVSPGCSSVHQKRSDPEPSCVSMRSDWSMDPPISFKSKDTPPDFSSVHQKSTESEPSCVSMRSDDESVDQPLHVRSGDTETDLSHEALNTFRSDLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIIPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLMNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHLLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDGFEEIKKPSLWSKVKDLLYLNSSQLVSLSELHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQIILQRLMILKSRSIQINKTVEYIKMKIRTIDSPEKFINLFHCLNELGDHSLVEEIQQYLKSGRINRAKLSESQWSAVAFVLLTSEKKLEEFHINEFVGETEKIFIFMKLLPVIRECRSVQLNNCGLTDEGCAALASALRSNPEHLRELNLSGNRLGDSVTLLSALLEDPRCNLEILWLSYCGLTDEGCAALASALRLNPEHLRELNLSHNNISKSTVKLLSDLKHNPHNKLETLYI", "length": 837 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B0M3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "si:dkey-7i4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESDEQHNDTLVQMGSSGNSGINADLRAEKEATVIAPLLNGNNITGPVTFNYCSNSAENEPQKYPKTADKHTEKQDDLKLQKILETHRTYMKKKVDCILDCTKENAEHFKAFYTELFIAEGDMQDVNQEHEILKIDDAFKKKKASLRSIRCKDIFAELKAKSEKNTVLTKGIAGIGKTVSVRKFILDWAEGQTNHDIHCVFLLPFREINLMTNEDFNLHEFLLKFYPELKELETSVLFQQCNLAFIFDGLDESRLPLNFKSRTLNNVEERSSVDMLFTSLVKGNLLPSALVWVTSRPAAANQIPPRYVGLFTEVQGFTDQQKEKYFRNRIADETQASKIISHIKTSRSLYIMCHIPVFCWITATVLQDILQRNIESIGTTLTEMYIHFLLIQMNMKSQKYDPEEEREYAKLLEANREVILKLAKLAFEQLKKENVVFYEQDLKDCGIDVNVEFTGMIAEIFKVEHGLHEAKVFYFVHLSVQEFLAAVYVFFCFLNRNTHELTFFFESSQNTPRELQFLFKKTFRKVKFHDLIKRATDKAMRSKRGHLDLFLRFLLGISLESSQNLLKGLFSHVIDTTRSIKKISPHFKHLQNKNISCDCSVNLFFCLLELKDHSLYEEIQRSLNSDRRPSKELSSSMCTVLTYIVLMSEKELDELNPKRFTSSQENYRKLVPAVRCCRKALFNGCGLDEMSFQTISSALQSSDSYLTELELSNNHLQDSGVKLLSDGLKSSHCQLNILRLCGCGLTDQSCESLSSALQSSNSVLRELDMSNNMLKDSGVKLLAVALKSLNCKLERLRFSMCNLTAESCESLSSVVELSNSVLRELDLSNNDLQDSGVKLLSDGLKRNCRLEILRLSGCMVTEVGCGFLSSALSSTTSTLRELDLSYNHPGDSGEKLLSDAHNQPNCRLCVDHGGEFRLTTGLHKYARFFTLDPNTANARLILSEENRKVTCVRKKQPYPDHPDRFEGYLQVLCRESVCGRSYWEIEWTGVVFISVSYSSIGRMGSDKECWFGFSNQSWSLFCSSDRCSFTHSSTEIDLPVKHTSSRIGVYVDHSAGTLSFYSVSDTVSLIHSVQTTFTQPLHPGFYISLGSSVKLC", "length": 1096 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YSM0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch211-181d7.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSHKQTLKYFSPVCSSVQQERSDSAEPSSVSVKSHWSIDPPPQMTERRDSLSLALQERSDSPEPSHVSMKSDWSIDPPPQMKEENRSLVQQERSPKSSCVSMKRDWSIDPPPQMNDEDGQKRLSLVQQERSDSAEPSLVSMKSDWSIDPPPQMKDGDRQKSLSLVQQERSDSPEPSHVTMKSNWSIDPPPQMTDRRDSLRQIPRPRPGAEEPISKKMKYDESVIKSQECMENPSLIFSHEVNTFRVNLLKKFQCLYEGMVTQDNPALLNEIYTELYITESESGEISNEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPETKEIDIFSDKYKILFIFDGLDECRLLLNFKSNEILQHVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLMAQINTKDMKYTGKKDKDMIFKLGKLAYEQLERGNVIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFIHLSVQEHLAALYVHLLFTNHNRNVFEQMTKKTSKTLDILDCFHSNSPENVLLSELHQKAVDEALQSKNGHLDLFLRFLLGLSLESNQILLQELMIKFRSSSDSSEKTVEYIKKRINNICLPEKSINLFYCLNELGDHSLVKEIQQYMDYGTLAETKISCGQWSALVFILLTVEQAMDVFELNKFIGLKKSSDEVLRKLLPVIKKSRSAIMDDCNITAEGCAYLASALGSNPSYLRELDLSANKLQDSGIKKLSKGLQDSHCKLEKLNLYHCGVTNEGCAALASALKSNPEHLRDLNLSENKIGNLGLTCLSEILKNSLCKLEILRLCQCGITDCTDLASALISNPEHLRELELSLNKIGDSGVTALCAAFEDPRFKLEKLGLSGCGLTDEGCAALTSALRSNHEHLRDLDLSGNKVDKEVKGSILQRILEKLNNIQILSV", "length": 1068 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YU37-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch73-24k9.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDNQTFSDAPVCSNESNPEFEPSCVSMKSDQSMDPPMKFKEGHTSADLSDRLNPPGSSCVSMKSDWSMDRPIQFKEEHSSADLSNKSNPGEPSCVSSKSDQSMGPPINVMEEHSAADLRLDPHLKQNGLRSNLLRKFQCLYEGTAMQGDPTLLNEIYTELYITESDSGEINNKHELRQIETRSRRSATEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEEKENQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEQFKVLFIFDGLDECRVSLDFKCDVKLHDVSESASVDVLLTNLIMGNLLPSALIWITSRPAAADLIPSEFVHRVTEIRGFNDPQKEEYFRKRIRDQFLADIIIINLKSSRSLHIMCHIPVFCWISATVLEKIFSQAQSGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEVRDEDMILKLGKLAFEQLVKGNLIFYEEDLRECGLDVTEASVYSGLCTQIFREEFGFYQGKVFCFVHLSIQEHLAALYAHHSLTNKNRNVFKQTKPSLLSKVLNQKKHDSLSVLHQRAVKEASQSKNGHLDLFLRFLLGLSLESSGTLLRELLTQTGSCSYNKEETVQYIKQKIRENRSPERSINLFHCLNELGEDSLMQEIQDYLSSGEIKETKLSSSQWSALVYVLLTSEKKMDFFDLSKFIGPQLRADVVLQKLLPVVKESRSVRLGDCKVTDKVCAALASALRLNSSHLTQLDLIGNKLGDSGVKLLSDGLKDPHCKLKNLMMRDCGVTDEGCAALASALRSNSTHLTELNLNENNLGDAGVKRLSDGLKGPHCKLEILRLWRCGVRDEGCAALASALSSNSTHLKELELSDNKLGDSGVKLLSDALKDPHCKLEKLRLNGCGVREQGCVSLALALRFNPSSHLTELDLTSNELGKSGVKLLSDLRDDPRYKLRHLACDMFGRIIVSSGGGRLDELLPTTSTET", "length": 978 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkey-165e24.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHRVRSGSCVSSSVSLKSDCSKEDPPKFSEKTPSSAQSVRSGLCVSSFVSLKSDCSKEDPPKFSEKTPSSAQSDEDELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNELEKFKQILQEENRQEFVKDYNENRSRITEAALDLTLFFLREMKQDHAADTLQDELLFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAVSRRHQSLETQVEFKHLFKAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQLFPETKGLNLTRSTQFKVLFILDGLDECRLPPNFAGNEMCCDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILNLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSQGKLAFQQLERNNVIFYESDLNDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEGIIAYIKQKLEGNLSPERSINLFYCLSELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELWKFQRSDECLIRLSAIIKNSKRALLQSCNLTVQSCKSLSSILQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLATCNLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSEHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDTLNLDHVGDMRITAGPRKYVCFLTLDPNTANTQLKLSKENRKVKHVREDLRIMRKDRRYPYHPDRFDPVFQVLCRESVCGRCYWEIDWSGDHGVFISVSYKSIRRKRGDACEFGCNAQSWSLLCLSSRFTFRHNNTHTHVPVKPLSRRIGVFVDHSAGTLIFYNIYKDTMSLIHSVQTTFTEPLCPGFGFYSGSSVKLS", "length": 1137 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1F5-1", "protein_name": "Protein NLRC3", "gene_name": "si:dkey-23k10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METEGPDSPEPSCVSLRSDHSKAHHVLFKDEDPFEYSSGQTGRSSPTPSHVSLASNMSINQPLEFKSCSNTLLLKEIQEAIQSVLRIRFQCLHEGLSKHSVLIPLNDIYTELYITEGEGGELNNEHEIRWIETACRRALTEDRPVNLNDIFKPLHGQDRPIRTVLTKGVAGIGKTVSVQKFIIDWAEGEANQDIWFIFPLPFRELNLLKDQSFSLKGLLQYFMNIELDISLHEGKIMFIFDGLDECRLPLDFHNNVKLCDVTESASVDVLLTNIIRGNLLPSSLIWITSRPAAADVVPSKCIHRVTEVRGFSDPQKEEYIRKKVSDQTLSDRIISHLKSSRSLYIMCHIPVFCWISATVLKKMLSEAESAEIPNTLTQMYTQFLMLQLRIKNEKAYDKKSSDIDIVLKLGELAFQQLEKLNLIFYKEDLREYGIDEQEASVYSGLFREESGMFQGKVYSFVHLSVQEHLAALYVYLYFVNENINKLNQPNFLTSILKCVPTVFDVYQTAVKKALQSTSGHLDLFLRFLLGFSLESNQNLLGDLQVQTESSSDSREQIVGFIKEKIKESPPPEKMINLFHCLNELNDHSLVEEIQDFLQSESRINMKLTASQWSAMVFVLLTSGQKLDVFDLNKYIGTYILPDESLQRLQPVLAASRTAKLCEHNLTKRGYSVLVSVLTSKTSCLRELNLTRSAVNDSGLKLLCSGLENPQCKLETLRLEFCGVSDKGCDFLASALRSNPSHLKALDLSGNTLNFTGLKNLLAEFQKPHCKLQRLCLRLCGLTDVGCDALASVLRSDPSHLTELNLSGNKLGDLGMKLLAGGLQNPHCKLQILRLGDCSITHEGCAALASALRSNPSHLRELDLSGNKLNNAGVQILSGELENPDCNLEILRLENCDVGEEGCAALAEALKSNPLTLKELDLCWNKLGNSGVQRLCTSLENPNCTLGVLRLTGCNISENGCAALASVLRSNPSYLRDLDLSHNDLRSSGVRLLSSALEKPDCKLEILRLEYCKITDDGCAVLASALKSNPSHLRELYLYMNSFNLTASGRQLLSKIKDDPHYKLQTLHYESHFFC", "length": 1074 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z5L8-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch211-207e19.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKDFNENRSRITDAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTDHEIRQIEAASRRHQSLEIQVECKHLFEAAEQHEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETEGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVDKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKKQGWFFIQISKNKGMIDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKGEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSADLSPAQWSALVFVLLTSEEELEVFELQKFQRSDECLIRLSAVIKTSKRALLQGCYLTVRSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLQFCNLTVQCCESLSSALQSSNCVLRELDLSINDLQDSGVKKLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKYVCFLTLDPNTAHTELILSEENREVKSVRENQPYPDHPDRFDYYHQVLCRESVCGRCYWEIDWSGDGVVCISVSYKSIRRKGGGDECVFGYNAQSWSLRCDSSRFKFWHNNTHTDLPVEALSSRIGVFVDHSAGILIFYNIYRDTMSLIHSVQTTFTEPLCAGFRVYYPGSSVKLS", "length": 995 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PCI8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTQTTIEKDYSPRFSLVHQKRSEPSCVSIRRDQSVAHPIDFKSEDTQTHLSSVHQERLDPEPSCVSIRSDRSVAHPIDFKSKNTHLSSVHQERSEPEPSCVSIRSDRSVAHPIDFKSEDTQTHLSTFHQKRKEADPSCVSMRSDTFMNQPINIKIGETQNDLKQNLLNTFRSNLLKKFECLYEGTAVQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQNKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSEKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCLNNNRNEFEQISKQSLWSKVRDHFHFNSSKLVSISKLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQGLMKLKIRSIQNNETVEYIKKKIRKINFPEKFINLFHCLNELGDHSLVEEIQQFLKSGGMNEAKLSSSQWSAVVFVLLTSEKKLEKFDINEFAARNNNTEQLFIFKKLQPVIRQCRSVQLSYCGLTDEGCAALASALRSNPEHLRDLYLSGNKLGDSVSLLSGVLEDPHCKLETLWLSDCGLTSKDSAALASALRSNPEHLRVLDLSWNRLGDSVTLLSAVLEDPHCKLETLLLRDCGLTDEGCAALASALRSNPEHLKHLDLSWSNLGDSVTLLSAVLEDPRCKLEKLGLSNCGLAEEGCAALASALRSNPEHLRGLNLSVNNLGDSVTLLSAVLEDPRCKLEKIKLSYCGLTDEGCAALASALRSNPEHLRDLDLSTNNLGDSVTLLSAILEDPHCKLEKLELKNCGLTDEGCAVLASALRSNPEHLRDLNLSWNNLSNSTKKLLSDLKDDPHNKLETLHTSLSV", "length": 1115 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPT2-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSKRKREDEDAASEISSASPGSSCVSVKSDQSMKKNLPDFSDASVTSDLSISKTINQRSASPEFSVLSMTSNRSIGQPENFSDEPVTFDSVLSDALDKPDYEKLHRIKDQHKTSMKNKYERLFEGLKLDETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHRASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFHVFYYHVNTTMDGLRNFASVENLIKGAVDKAIESENGHLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLFREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCGIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTRQKLNWDHGGHFRITPGLRKYACFLTLDPNTAHNQLILSEDKRKVTHVKDPQQYTDYPEKFVHQEQVLCKETLTGRCYWEVEWSGEGTDIAVAYKGIRRKAGSDCWFGYSEKSWSLFYTGNGFNVWHNNKSQIIPAPSPLSNRVGVYLDTESGSLSFYSVSDTHTLTHLHTFNTTFTEPLYAGFRVFDSSLSLCNI", "length": 993 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PSD3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEEQGKMSLSEKHSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKPMSAKSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKQTSAKSVISDSCVSGSVFVKSDCSKDGDLPNFSEETPSSGKSFEHKTSDSDFQTHRKHKGFQDGLLGIFQDLENQIMNYLKHELEKFKKILQKENIIDFVKDFNENRCSIKEAALDLTLYFLREMKQEESADTLEDELIFIHQLKCGLQKKYQCVFEGIAQQGDSRLLKNIYTDLYITQGGSEQVNTEHEVRQIEVASRRHEAQELQVECRHLFEASEQDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQEISFIFPLPFREMNLKEKETLSLMELITQFFPETKGLNLTRRNRFKVLFILDGLDECRLPLNFAGNETCCDVSSPASLDVLLTNLIKGNLLPSALIWITSRPAAASKIPPDCIDRLTEIRGFNDAQKEEYFRKRLTDENQAKEIIDHVKQSKSLFIMCHIPVFCWISATVLQNILQEKRNNDVKHNQADDASKTLQESNTEDTPKTLTQMYTHFLRFQIQQSRRKYNGEYTPDVSWDKDAILSLGKLAFHHLLNNNLIFYDTDLEACGIDVYKASVYSGMCTQIFKEETGIILGTMYCFVHLTLQEFIAALYAHLILDTNKKSVFDQDSKKINESMIDLLKTAVDKALESDNGHLDLFLRFLLGLSLQSNRRILRGLLTPQDQDDQSTEKILQYIKQKFDANLSPERSINLFYCLNELNEQTLVKEIQTHLSKGSLSSADFSSAHWSALAFVLLTSDEEMEEFELQKFHKSDECLIRLSAVIKTCKRALLNDCNLTDRSCSALATVLESDTSLKELNMSNNNLQDSGVKLLCTGLKDMKCELEILRLSDCNITEEGYKALASALRSNPSHLLELDLRGNDPGESGVKELDDLLQDPNCTLKTLRFLSPSAEESCQFVNGVVGKNPLLLKTLNLNDFRSTRNHPFIYEIEDTQVNHLAALLQDKHCRVNMLILGGCSFTDDQWESLTSALKLNPSHLRELILMWNGPGESGVKILSDFLIEPQLKLEKLCLCYCSITEERCEILTSALKSNPSHLRELNLSQNIPGDSGMKNLSDLLMNPQSKLEKLQLCKCSITEEQCVILTSALKSNPSHLRDLNLSLNNLGDSGVKTLSDLLMKPHLKMEKLWLCKCSITEEQCVILASALKSNPSHLRELSLSENNLGDSGVKNLSDLLMKPQFKLEKLHLSHCSITEEQCEILTSALKSNPSHLRELDISKNQIRNTGVNLLCDVLNNSDCKLETLRLNDCGITDVSSLTQCLTNTKALQFLKVLYLRENHIGDSKQELSDVVRDSNCELSVDEFSLPDFGQIKDIKCCIS", "length": 1370 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCS9-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLQKKNEDEDEESASEMSYPPPESSCVSMKSDWSMVYPPDLSDASVTSDPNNSKRKGQHLEFKESSCVSVMSNRSITPPEMKKIGLKSEDNMLEKIKNKHKTSMKHKYERLFEGVKLHENQTLLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVGVSDASVYSGICTEIFKEESVIQQRKVYSFTHLSIQEFLAAFYVFYYHITCSTEACFDSLHDLQRRAVDKAIESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITSGLRKYACFLTLDPITAHTQLQLSEENRKASIVTDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGLVAVAYKGIGRKSGFDCCFGHNEHSWCLYCSDEVYSVWDNNKSVDVFGPSSRTNRVGVYVDVPSGCLSFYSVSDTNTLTHIHTFNTTFTEELYAGFKVYPGSSVSLCPVKPAEVPP", "length": 988 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUW9-1", "protein_name": "NLR family CARD domain-containing protein 3 isoform X1", "gene_name": "si:ch211-196h16.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKGNTGFRVKPPEPSGVSMKSDRSMHHPLKFKGGIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDPMFRPPEPSVSEKSGQSVDPTLKFSVHTCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDIGEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSINLFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQLDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLRLRCCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLCRCGVSDEGCAALVSVLSSNSSNLRELNLTENKVGDSGVKLLSAGLKENSKLEKLWLFICGVSDEGCAALASILRSNSSNLRELDLTGNKVGDSGVKLLSAGLKDPHCKLEKLTLDFCGVSDEGCAALASALRSNSSNLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC", "length": 1041 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32T552-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:ch73-50f9.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSGKHSVRSGSCVSRSVSLKSDESRKGLPPEFSEQPPSSNRSVEYELSDSVDKTHCNRKSFTDHLLRIFQDLESKIFKVLKNELERFRQILQGENTQDFVKGSNENQSSITKSALDLTLLFLREMKQDEVADTLENELLFINRLKSSLKKTYQSVSEGIAQQGDSTLLNNIYTDLYITQGANEQVNTEHEIRQIEAASRCHKSLEIQVECKHLFEAPEQDKQIRTVLTKGVAGIGKSVSVQKFVVDWAEGKANQDISLIFPLPFREMNLKEKEKQSLKDLITQLFPEVKGLNLTRRTRNKVLFILDGLDECRLPLNFAGNETCHDVSAPAYLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLADQNLAMEIIEHIKQSKSLHIMCHIPVFCWISATVLQNVLKETKVKHKACAKTLQESPKTLTQMYTHFLRFQMQQSRQKYDGKNTDGVSWDQNFILSLGKLAYQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKQETGIILGNLYCFLHLSIQEFIAALYGHLYLDIKKKSVFTGQKHKNKGMTHLLKTAVDKALESDNGHLDLYLRFLLGLSLQTNRQLLRGLLTQQDKSDQSKEEIVVYIKQKLEENLSPERAINLLYCLNELNDHSLMKEIQSHLRDGSLSSADLSPAQWSALTFVLLTSEEELDEFDLQKFKKSDECLIRLSAVIKSSKRALLQCCNLTAQSCESLSSALQSSNCVLRELELSNNDLQDSGVKLLSCGLRSLNCPLEILRLQCCNLTAQSCESLSLALQSSTCVLRELDLSNNDLQDSGVKLISNGLKSCKLEILRLSGCMVTETGCGFLSSALSSNPTHLRELDLSYNHPGVSGVKLLCQKLEDPNYTLAKLNVDHAGAKRITAGPRKWISHLTLDPNTANTELSLSAENREATRVIEKQPYPDHPDRFDYHPQVLCRESVCGPCYWEIDWSGDVGACISVSYKSVSSKGNDEFGCNDQSWSLSCYSSRFSYGHNNRWTDLPVKPISRRIGVYVDHRAETLRFYNICGNTVHLVHSVRTTFTQPLYAGFKIYPGSSVKLC", "length": 1099 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TA29-1", "protein_name": "NLR family CARD domain containing 9 isoform X3", "gene_name": "nlrc9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTKISKDEDYSPRFSSVHQERSDLEPSCVSMRSEQSMGSPMHFRSEDTEADLSSVYQKRSDPEPSCVSMRSDWSMDLPYNFRSEDTPTDLSSFHHKRTEAEFSRVSMRSDMFINHPINIKNVEAQCNIRQNLLNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFESAVRLCDISESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPMFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDEFEQIKKQSLWFKVKDLFQLNSLECVSLFSLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQRLMKLKSRSMQTNKTVKYIKMKIWTIDSPEKSINLFHCLNELGDHSLVKEIQQYLKSGRINRAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAGNNENKKQKVFQKLLPVIKQSRSVLLYNCGLTEMDWDNLTSALRSNPSDLRVLNLSRNILGNSVTLLSAVLEDPCSKLEKLWLSDCGLTDEGCAALATALRSNPEHLRELNLSWNNLRDSVTLLSAVLEDPRCKLETLWLSKCGITGKSCAVLASALRSNPEHLRDLDLSGNKLGDSVTLLSAVLEDPHCKLKILWLSDCGLTDEGCAALASALRSNPGQLRVLDLSENKLKNSGVMQLCAVLEDPHCKLDKLGLYDCSLTDEGCVALASALRSNPEHLRELDLSVNKLRDSGIKLLSAVLEDPRCKLEKLWLSNCGLTDEACAALASALRSNPEHLRELNLSKNKLGESDVKLLSDLKDDTHYKLKELNY", "length": 1079 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TJY6-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkeyp-100h4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQQIQETRLKGDTRASQTISSPSSSCSMAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKDCPPVFSGETPSSAQSVEFESADSGDETHRRHKSFTDNLQSIFQNLESKMFTFLKNELEKFKKILQENRQEIVKEFNENRSRITEAALDLTIFFLREMKQDQAADTLVGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVKCKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDDQKQEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGFVLHTMYCFLHLSIQEFIAALYQHLILDNDKTQAEKSRDESMIDLLKAAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEANLSPERSINLFYCLNELNDQSLLKQIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAIIKTSKRALLQGCYLTVPSCESLSSVLQSSNCVLRGLDLSNNDLQDSGVNLLSDGLKSQHCKLETLRLVMCNLTVESCESLSSVLQSSNFVLRELDLSNNDLQDSGVKLLSDGLKTVNCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVELLFEKLADPNYTLDKLNLDHGGHTRITAGPRKNACFLTLDPNTTYAFLILSEENREVKTVREYQLYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDDYVDISVSYKSIMRKGVDPECVFGRNAQSWSLCCDSSSFTFWHNDTDTRLPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLWPGFTVWCQSSVKLC", "length": 1125 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TMV3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like", "gene_name": "si:ch211-197e7.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDWSKEDPPKFSEKTPSSAQSVRSGSCVSSSVSLKSDRSKEHPLPNFREKTPSSAQSVEHELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNEMEKFKKILQEENRQEFVKDYNENRSRITEAALDLTLFFLREIKQDQAADTLQDELFSINQFQCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNNEHEIRQLEAASRRHQSLETQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNKTCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKILFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALENENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDESKKKIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFMLLTSEEELEEFELRKFQRSDECLIRLSAVIKTSKKALLQSCNVTVQSCKSLSKVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLAMCNLTVQCCESLSLALQSSNCVLRELDLSNNDLQDSGVKLLSNRLKSQYCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDKLNLDHGGEKRITAGLHKYVCFLTLDPNTAHIQLILSEENRKVKPVREDMMMMRKDQPYPDHPDRFDGLYPQVLCRESVCGCCYWETDWSGDGGVCISVSYKSIRRKGGVECEFGRNAQSWSLHCSSSRFIFIHNNTETRLPVKRLSKRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRVYSGSSVKLS", "length": 1140 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TPE7-1", "protein_name": "Protein NLRC3 isoform X4", "gene_name": "si:dkey-11n14.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKYSVRSGSSSSVSLKSDWSKDEPPKFSEKSPSSARSVEYELPYSGDKTHRSHKGFTKDLPRIFQNLESKIIRYLKNELEKFKKILQEENRQDFVKHFNENRSIITEAALDLTLFFLREMKQDEAADTLEGELFFINQLKCGLKKKYQNVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTTGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKENQSLKDLITQFFPQTKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTKLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISANVLLNILKENRNTELKHRDNSETLHESPKTLTQMYTHFLRFQIQHSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYDSDLKDCGIDVYKASVYSGMCTQIFWEETGIILGTMYCFLHLSIQEFIAALYQHLFLDSDKKHLSIFRQKSKNKVMTDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQNDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSADLSPAQWSAVAFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQGCNLNVRCCESLSSALQSSNCLLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDTLNLNHGGEKRITAGPRKYVCFFTLDPNTANTRLILSKKNREVKCVRENQSYPRHPDRFDDHPQVLCRESVCGRCYWEIDWSGGNEVCISVTYKSIRRKRGYECRFGYNAQSWSLICSSSRFSFTHNDTHTDLPVKPFSRRIGVFVDHCAGTLIFYNIYRDTMSLIHSVQTTFTEPLIPGFWVYSGSSVKLLKTEERFTQNPLQDQ", "length": 1060 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQ28-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:ch211-226o13.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTHTSGDLDLFTSCSVDGDDQTRDLQQDSLQPEHDELQRAKNQHKTSMKNKYERLFEGINHGETQKFLNRIYTQLYIIEGESEGVNREHDVLQIEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQGVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITARPAAAHQIPSTYIHRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDQEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFHCYLTDKREPVMLLYESKYSDDEDVSDGNEYEDSDVQFLQSSSEFSLCHLLSLAIYKAVMSSNGHLDLFLWFLLGVSLESNQRLFQDLLTHTEESSESIRIITQDIKDKIKTDDDLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSERELSPAHCSTISYMIEMSEEPLDELDFNKLNTSPVGRWRLIPAVRNCRRALLQWSYLSVQYCESLFSALKSSNCVLRELDLSTNDLQDSGVKLLSDGLKSPNCKLETLRLQCCNLTAQSCESLTSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCKLETLRLVMCNLTVQCCESLSLALQSSNCVLRELDLSNNGLQDSGVKLLSDGLKSQHCKLDTLRLVMCNLTVQSSESLSSALQSSNCVLRELDLSTNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGLHKYACFLTLDPNTTYAFLILSEENREVKRVREYQQYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDGCSVCTAVSYKSIRRKGRGAECLFGRNAQSWSLCCSSSSFIFRHNYTRTELPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFTVWCQSSVKLC", "length": 1145 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQA8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-29j8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEEQVKDSLSEKQSVRSGSCVSSSVSLKSDNSKGGRTPNFRGKTPSSVKRFFHLGKSKHPPSNLREKTPSSAESFQYELPDSRNKTHRSQKSFRGHLQKIFENLESKIIKFVKKELKNFRKILQNENRQEFVKEFNENSSGITEAALDLTLFFLREMKQDQAADTLQGELLYINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSVVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDTQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVLCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNKVMINLLKTAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQCCNLTVQCCESISSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQQCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGEKRITAGPHKYVCFLTLDPNTAHTRLILSEENREVKCVRENQPYPDHPHRFDYYLQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGAECAFGRNAQSWSLICSSSSFTFRHNNSHTDLTVKPLSRRIGVFVDHSAGTLIFYDIYRDTMSLIHSVQTTFTEPLCPGFYVSYGSSVKLS", "length": 1064 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TTK4-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAMNRLMTDMLEELVEAELKQFTRQLWMGVKPGVDPIPRGKLENKDRQDVVDCMVQHYSKDAGKIAVQALRSIKQNERADRLELNLRKDDDFLGEVLKKHKESIKASVDVFEGKKDNKTDINKVYTELFITEGDMTDVCKEHEVQKFDLALQMPRSEDKPIDCNEIFNLLRGKDKGNVVLTKGIAGIGKTFSVNKFILDWAEGRANLDVDCMFLLPFREINLMIKDGDVSLHKFLLKLFPDITGVETTPFYEKCKLLFIFDGLDESRLDLNFNLSSVDDVHSCASIDGLFTSLIKGRLLRSSLIWVTSRPAAANRIPSYHVGLFTEVRGFTDKQKEEYFRKKVPDEDQASRIISHIRTSRSLYIMCHIPVFCWIIATVLQDILQKNKGEDIPSTLTEMYIHFLLIQMNIKNQKYDEKLIRDRTELLGSNRDMISKLAKLAFEQLKKENVMFYREDLAACGINADEEFTGLCTEIFKKDSVLHELKVYYFIHLSVQEFLAALHVFLCYLELEKDMNLTDSDLMFFLEDSRPKQKELLHVLLRKAIDKAEKSDRGHFDLFLRFLLGISLESNQKLLIGILNETKNSKQSISKTVQYLKQLQNNDKCPDKSINHFFCILELQDRTLYQQIMKYLRSKTNRPKVMSRSNCSALVYVLLMSQEVLDKFNPKLFNKTYAGCRILVPAVRCSRKALFSDCGLTETCFETVALALQLENCPLVELDLSYNYSLEAAVNVMCAGLKSPHCHLESLRLAGCHLGQDSCMQVVSALQSISHRLKELDLSGNDLQDSGLQKLLQGMENTEKRLQVLRLSWCNLTEMSCQQLSTILSSNSVFRELDLSNNDLQDSGVKLLSDGLKSPNCKLKILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHCKLKTLKTDPMGDHLMKPGIVKYAFNLTLNPNTAHVHLLLSDGDRKVTLKEKQPYPDDPERFEEHHQVLSRESLSGRCYWETEWTGQEGTVGVAYESIPRKPDDLLYGRCMLGNNIISWKITCGSRTHVSHAEEDITVKSPSSGSCKRVGVYVDTTAGVLSFYHVFDTLTHLYTFLMPFTQPLYAAFRVDGESVSICPIP", "length": 1114 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TUF4-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch73-236c18.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHHCGNEEVDREEKEKHGAEHSCVSMKSDQSMRNPIAFTDKAVTFDLRSVASSSSHFETHTVQEKTDKGLQTQIFETEELQRVKDQHKTSMRKKYELLSEGIKVKETGTQLNRIYTQLYIIEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFYVFYYHVNTTMMGLKTFASLQKLLKGAVDDAIESKNGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCRLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRIKPGLKKYACFLTLDPNTAHVQIQLSEGNREARNVKDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYCCDTNYTVWYNNESADIIAPSARTNRVGVYLDVSSGSLSFYTVSDANTLTLIHTFNTTFTEPLYTGFGLYPESSVSLCQI", "length": 969 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HUA8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 1 homolog isoform X1", "gene_name": "LOC103910107", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDQDSERAQFVDAHWKTLVQRVIMVMAIADELQSDGMLEWEPYCKIKAAVTNQQKMRELYEVLQSGGDQVKSAFYSSLEKHEPYLLGDLGSIKLMGESLADCLNKYKMWIQKEYEYVTEYNSLPGENVLLSERFTQPLIIMRHRERREREEEMCSVGESFQQLLVSRNNADKDSSILDALFGADSKGISPNSVILQGNSGNGKSFTAQKIMLDWASGKLCKVEFDCLFHLKCKEVNHVSGEQSLTELLSYNSNLTSEQISRILQKSSEKVLILIDGFDELRFSFSDFSDHLKLKDLSEKAPREASLKVLLMGHILSKTSLLVTTRSTATNTLDSLLKHPKRFTEIMGFSEREVKEYFQKFFQDEELFIKAYEYVRSNETLITACSIPVICWIICTVLRERFSEGSDLTSGLETTTSIYVDFVCTLLEHHSQGLSQPVPTLLRSLGQLAERGMLDTQVLFEEKSVDEMVSASPFLCKFLFKRRIRKETMFSFMHLSFQEFFTALYYISQEEREFLDKLTERFHSQTQSYLSLYLDKDFPLKYGCPEPHFLPVVQFLCGLSNSEVSRSLQEMYNLSVPSFVQPQLREWILDMSKSGVYSYLPFILHCLYELHEKEFVQKAMEAWLELDMSWDPLSRTDCWALLYCLDCCPHFRSLKLNFAASELKMLQDVLCRTPKLGLTVQNVSDTDVTVLLSALGEGKQLGELKLNSSCLSDQSVQQVLKALHKQKKVGGLQISVKSITADTALILTDFLQSCSKAEWEEISGSLSTSDVESLCSSLRLFSFEGKLVVNVVRLCLSIQNQPSLSEIILNCPRSEASNIDIKSFTESFHNINCIAEESVDFDRNLHALLTLLTSMSGLSALNLSVPFLTETWASRVLFLVESSPKLTVINFHAGSWCSDGVKWLPGLLLEEGIKLLKESAKRPECIVNIRGFRCSKSSERCSRHTEHIDQLSCNQRVTIQFCGDQCTEDIKLKLVLPDEN", "length": 979 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HZJ9-1", "protein_name": "Uncharacterized protein si:ch211-149a19.3 isoform X1", "gene_name": "si:ch211-149a19.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDKEASNDGDFSSRRSHFQSQKSNTSESNPEITPEDLSAKKLIKMFEKRTPDNQSKFNNQKSNTAKSIRSDRSIQNPVKIKEIRTPADLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPKPMPRSIKSDQSTPELDKVDGGHTSTALSSQRSNPPDPKPRSIKSDQSTPEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGIGCQRSNPPDPKPRSIKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPESSLVSLKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSMPEPIKFDGGHTPTGLSETSTNDQFMNKQVKIKRRHTLTGLSKTSINYQFMEKQLKTERRHTSTGLSLNSKLFENLLKSNLLKKFQCVSEGTSILGNPTLLNEIYTELYITESDSGEINNEHELRQIETQSRRSAKEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEKNKNQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEHYKVLFIFDGLDECRVSLDFDSGVKLHDVSESASVDVLLMNLIMGNLLPSALIWITSRPAAADLIPSGFVHRVTEVRGFNDPQKEEYFRKRIRDQSLADTIISHLKSSRSLHIMCHIPVFCWISATVLEKIFSQAERGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEDKDMILKLGKLAFEQLQKGNLIFYEEDLRECGLDLTEAAVYSGLCTQIFREEFGFSQSKVFCFVHLSIQEHLAALYAHHFLTNNCLNKHWKTFNPLSFLHQRAVNEALQSKNGHLDLFLRFLLGLSLEFNQTLLQELLTQTGSCSYNTEETVQFIKQKIREINSPERSINLFHCLNELGDQSLMKEIQNYLRSGEIKETKLSSSQWSALVYVLLTSEQEMEDFDLNQFIGTQNTADEVLQKLQPVVKESRSVQLSGCSVTDKGCAALALVLRSDSSHLRELDLSENNLRDSGVKLLSDGLKDPHCKLEKLRLSDCGVTDEGCAALASALRSNSTHLTELDLSLNNLEDSGVKLLSDGLKDPHCKLEILRLSDCGVTVEGCADLASALRSNSTHLRELDLTLNNLEDSGVNLLSAGLKDPHCKLEKLRLSDCGFTDEGCADLASALRSNSTHLTELDLSLNNFGDSGVKLLSDGLKDPHCKLEKLRLSYCRVRAEGGVALASALRSNPEHLRELDLSENKLGNSGVKMLSELKNDSRYKLDTLKF", "length": 1375 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCJ8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12-like isoform X1", "gene_name": "si:dkeyp-77c4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKEEHLPNFREKTPPSAQSVRSGSCVSSSVSLKSDWSKRDPPNFREKTPSSAKSSVHQKRAEAEPSCVSMKSDWSMNRPITFRSKITQPAISVDRDDQTGHLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSAQKFILDWAEEKDHQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCALTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQIHMRKQKYEERDPEKLLQSNRGVILKLAEVAFSQLMKGNVMFHEEDLTESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVLYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESTESIRRITQHIKDKIKRDKRLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDELDFNKLNTSAEGRRRLTAAVRNCRRALLQGCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLQWCKPTVQSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLVMCNLTVQCCESLSSALQSSNYVLRELDLSNNDLQDSGVKKLSDGLKSPNCKLETLRLVMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKRNCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKWVCFLTLDPNTAHTQLILSEENREVKRVRENQPYPYHPDRFDVHRQVLCRESVCGRCYWEIDWSGDVGVCISVSYKSIRRKGRGVECWFGYNAQSWSLICSSSRFSFRHNHTDTDLPVEPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFTVYSGSSVKLS", "length": 1235 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCK2-1", "protein_name": "Uncharacterized protein si:dkey-26m3.3 isoform X1", "gene_name": "si:dkey-26m3.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGYVFVLSSLCPVFILLQFLLEFLLEIKLFRSIMGNTHAAGDQDLSTECSSVHQKRAEAEPSCVSMKSDASMGVPITFKSENTGPAVSSVHQKRAEAELSCVSMKSDASMNPPIEFKSGNTGPAVSVDRDGQTGDLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEQIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKDNQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPKLEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTEPSSVAVLMRSLLKGDLLPSALIWITSRPAAAHQIPSTYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLDSNQRLFQDLLTHTEESSENIRRITQYIKDEIKRGKHLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELTPAHCSTISYMIEMSEEPLDELDSNKFNTSDVGRRRLIAAVRNCRRALLQRCELTVQCCESLSSALQSSNCVLRELDLSNNDLQDSAVKLLSDGLKSQHCKLETLRLMTCKLTADSCESLSSALQSSNCVLRELDLSNNDLPDSGVKLLSDGLKSQHCKLETLRLQWCKLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLAMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKTVDCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKYVCFLTLDPNTANTRLILSEENREVKHVRENQPYPDHPDRFDGVYQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGVECWFGSNAQSWSLSCSSSNFSFRHNNTRTDLPVKALNRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRIYPGSSVKLS", "length": 1239 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCL0-1", "protein_name": "Uncharacterized protein si:dkey-165o8.1 isoform X1", "gene_name": "si:dkey-165o8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDQSKDHPPYFREETPSSAESVEYESADPGDETHRRHKSFTDNLQSIFQNLESKIIRFLKNELEKFKKILQEENRKEFIKEFIENRSIITEAALDLTLFFLREMKQDQAADTLQDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNKIYTDLYITQGASEQLNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCGDVSSAVSLDVLLTNLIMGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILRLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLDRNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLDIDKKRGWFLIQISKNKSMIDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQFCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKCRTTHTQTHTHTHTHIHTHTHTHTHIHTHTHTHTHTHTRAHTHTHTRGLQQDRANVGPHTYTHTHTHTHTYTYTHTHTHTHTHTHTHTRITAGPRKCRTTHTHTHTYTHTHTHTITHTHLHIHTHTCTHTHTCAHTHTHIHTHTLTHTRTYTHTHTHTLPLTHTHTHTLSHTHTHTHTNIHTHSLTHTNIHTHSLTHTNKHTHSLSHAYTHACMHALSHLHTHTHALTHTHTHTHTHSLTHTHICTHKHTHTLSHSHKHSHTHTHTHTHTHTHTQARAHLHKHTLSHTHTHIHIYTHTYKHTHILSHTHAHTHTHTQARALTQTYSLTHTHTHTHKHTLSHTHTHIHHTHTQIHIHSHKTHTHARTHTLSLSLTHTHTHTHTHTHTHTHTHTHTHTQLWL", "length": 1266 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JD10-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch211-203c5.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVGYDTECSVCVVCSRMLVCVCVVHLRCSMAEERVKDSLSEKHSVRSGSCVSSSVSLKSDWSKGNPPQFSGESPSSAQSVEYESADSGDETHRRHKSFTDNLQSIFQNLESKMIRFLKNQLEKFKKILQEENRQEFVKEFNENRSIMTEAALDLTLFFLREIKQDQAADTLQDELLYINQLKCSLKKKYQRVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCHDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESSKTLTQMYTHFLRFQIQQSRKKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDRDKKHGLFLQIGKNKGVTDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKKKIIAYIKQKLKGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGRLSSARLSPAQWSALVFVLLTSEEELEEFELHKFQRSDECLIRLSAVIKTSKRALLQSCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLEILRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPHKYVCFLTLDPNTAHTRLILSEENREVKRVRENQPYPDHPDRFDGYVYPQVLCRESVCGRCYWEIDWSGDDGVFISVSYKSIRRKGGGVECWFGCNAQSWSLLCDSSSFSFRHNNTLTDLPVEALSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCAGFGFSSGSSVKLS", "length": 1073 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z7N0-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Dmel\\CG8197", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCDVLLPCEYNPKECPSPAAEKSRLFTILLLYCWQREYDKRPYRQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLRRPQLSVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPREFFVMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANRLLGMSLSLDTEKISSVLSSLLMQNTLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLAMKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISYTYDEALQDYRVVPWR", "length": 387 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZAD9-1", "protein_name": "NLR family, pyrin domain containing 9", "gene_name": "Nlrp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDTSGYGLLKHLRKLSDGEFWSFKELLRKEPEKFKLKPISWMKIENASKEELVMLLNTHYPKQAWDMALSLFLQVNREDLSIMAQKKRRYKQTKYKKFMKTTFQSIWTLESNICIPDRSYHLIVEHQYRKLQNIFDSESEPVTAVVTGPTGEGKTVFLRKAMLDWASGILWQNRFQYVFFFSVLSLNNTTELSLAELISSKLPESSETLNDILSDPKKILFILDGFDYLKFDLELRTNLCNDWRKILPTQIILSSLLQKIMLPESSLLLELGHISLPKIFPLLQYPRDITIQGFSERCLKTYFISFFNTEKGIEVFENLKSNQMLKLCSNPYLCWMFCSCLKWQFDREEEAYFQAKTDSVFFTSFMVSAFKSAYASNPPKQNRAQLKSLCTLAVEGMWKQLFVFDSEDLRRNGISESDKAVWLRMKFLQNHDNHIVFYHPTLQLYFASMFYFLKQDKDTHVPVIGSIPQLLRKIYARDHTQWLQIGIFLFGLATEQVASLLKPYFGFIQHRDVRQEVMRYLKSLSQRECCEKLERPQNLFACLRDNKEEKFVREVVDLFEEITVDITNSHVLSIIANHLQKSSKLKKLHLHIQKRVFLEIHDPEYSDSETFTQDKKNAAEYWKKLCHIFVNLHVLDLDSCNFNKQVIEELCNVLSPSPKIPLMAFKLESLLCSFMTNFGDGSLFHTLLQLPHLKYLNLYGTNLSNSRIENLCSALRRSTCKVEELLHSEMSFPLSTDFIVSHKFGLGKCDISSEACGIIATSLMNSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLETLMLSYCCLTFIACGHLYEALVSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCILKELWLSGCFLTSECCEEISAVLTCNNNLKTLKLGNNDIEDTGVKHLCEALSHPNCKLECLGLDLCKFTSDCCEDLASALTTCKTLNSLNLDWKTLEHSGVVALCEALNHKKCNLKMLGLDKSAFSVESQTLLQAVEKKNNNLSILHYPWVEEERKKRGVRLVWNSKN", "length": 1022 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZP31-1", "protein_name": "NLR family, pyrin domain containing 4", "gene_name": "Nlrp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEILQLRLKQISWTKVKKASREDLANLLLKHYEEKQAWDMTFKIFQKMNRKDLIERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKAQDLFKQKFTQDDCDRFENLLVSKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGIVFQNKFSYIFYFCCQDVKQLKRASLAELISREWPNASAPTAEILSQPEKLLFIIDSLEVMECNMSERESELCDNCTEKQPVSLLLSSLLRRKMLPESSFLISATPETFEKMEDRIECTNVKIITGFNENNIKMYFRSLFQDKNRTLEAFSLVRENEQLFNVCQVPVLCWMVATCIKKEIEKGRDPVFICRRTTSLYTTHIFNLFTPQNAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFSEEALRRNGILDSDIPTLLDRRILERSKESESCYIFLHPSLQEVCAAVFYLLKSHLDHPSQDVKSVEALLFTFLKKAKVQWIFLGCFLFGLLHESEQEKLEMFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEAFLMQAMNCMEQINFVAKDYSDVIVAAYCLKHCSTLKKLSFSTQNILSEEQEHSYTEKLLICWHHMCSVLISSKDIHVLQVKDTNLNETAFWVLYNHLKYPSCTLKVLVVNNVTFLCDNHLFFELIQNQRLQHLNLSLTFLSHSDVKLLCDVLNQAECNIEKLMIAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLCKALCHPDCILKHLVLANCSLSEQCWDYLSEVVRRNKTLSHLDISSNDLKDEGLKVLCGALTLPDSGLISLSVRHCLITTSGCQDLAEVLRHNQNLRSLQVSNNKIEDAGVKLLCDAIKQPNCHLENIGLEACELTGACCKDLASAFVHCKTLWGINLLENALDHSGLVVLFEALKQQKCTLHVLGLRITDFDKETQEFLIAEEEKNPYLSILSNV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZUH1-1", "protein_name": "NLR family, pyrin domain containing 4A", "gene_name": "Nlrp4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLGLKQVSWTEVKKASREDLASLLLKHYEEKQAWDMTFNFFQKINRKDLIKRAKREIDGYPKLYRAHLKTKLTHDSSRIFNINIQDFLKEKFTKDDHDRFETLLQSKGTESKPQVVVLSGVAGIGKTLMLKRLMLAWIEGLVFPYKFSYIFYFCCQEVKQLKTASLAELISREWPDPSAPIEEILSEPEKLLFIIDSLEGIECDLFKCDSELCDNCMEKQPVNILLSSLLRKKMLLEASLLISTTPETFEKMEDRIEYTHVKIITGLNESDIKMCFHRLFQDRNRAQEAFSLVRENEQMLTICQVPVLCWMVATCLKTEIEKGRNLVSTCRRTTSLYTTYIFNLFIPQSAHSPSKKSQDQLQGLCSLAAEGIWTDTFVFTEEALRRNGILDSDIPTLLDIGMLGKMGKFENCYIFLHPSLQEACAAIFYLLKSHGDHPIEDVKSVEALLFTFLKKAKVQWILGGRFIFGLLHESEQKKLEAFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEDFLMEAMNYMEQINFVAKDYSDVIVAAYCLKHCYTLKKLSFSTQNILNEEHEHSCMENLLTCWRHICSVLINSKDIQELQIKDTNLNEPAFSVLYNSLKYCNDTLKVLVENNVFFLCEKYLFFELIQNCNLQHLNLNLTFLSHSDVKLLCDVLNQAECNIEKLEVAACNLSPDDCKMFASILMSSKTLKQLNLSSNILGKGISSLCKSLCHPDCILEHLVLAKCSLSDQCWDYLSDGIRQNKTLNHLDISSNDLKDEGLKVLCRALALPNSVLKSLCLRHCLITTSGCQDLAEVLRNNQNLTSLQISYNKIEDAGVKLLCDAIKQPNCHLEDLGLEACELTGACCEDLASTFTQCRTLWGINLLNNTLDYTGLVVLCEALRQQKCTPHVLGLRITDFDNETQAFLVAEQEKNPDLSILSGV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A1P8-1", "protein_name": "NLR family, pyrin domain containing 4B", "gene_name": "Nlrp4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLFSDFGFMWYWKELNKVEFMKFKELLILEILQMGLKQISWTEVKNASREDLAILLVKYCEGKQAWDTTFKVLQKISRHDLTERATGEIAAHANIYRAHLKKKLTRDCSRKFSISIQNFFQDEYDHLENLLIPKVTEEKPQLVFLKGIAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCQDVKQLKTTSLTELISREWPSSSAPIEEILSQPEKLLFIIDSLEGMEWDFTKQESELCDNCLEKQPVNVLLSSLLKKKILPESSLLISATFETFEELKDWIEYTNVRTITGFKESNIKMYFHSLFQDRNRALEAFSFVRENEQLFTLCQAPVICCMVATCLKNEIEKGKDPVSICRRTTSLYTTHIFNLFIPPNVQYPSKKSQDQLQGLCFLAVEGMWTDISVFSEETLRRNGILDSDIPTLLDIGILEQSRESQNSYIFFHPSVQEFCAAMFYLLQTHMNHPSPDVLHVEKLLFSFLKEVNTQWIFLGRFIFGLLNELEHEKLEAFFGYQLSQQLKQELFEWLELLLDPEVKVNTMKFFYCLFEMEEEVFVQSAMNCREEIDVVAKDYYDFIVAAYCLNHGSALRDLSISTQNVLNEKLNQRYMENLLMLWHNICSVFARNKDIHILQMKDTIFNEPVFQILYNYLKNSSCILEVLVANDVSFLCDKYLFFDLIQSYNLELLDLSGTFLSHSDVVILCNILNKAEYKIQELELANCSLSEQSWKYISDVLCQNKTLRHLDISSNDLKDEGLKVLCKALTLPDSVLLTLSVKACFITTVGCQYLAEVLRNNHKLMFLTLSENKLEDSGVKLLCDAIKHPRCQLAQLDLEACELTGACCEDLASTFTQCKTLGWINLVKNALDFNGLVVLCKALKQKTSNLKELRLRITDFDNKSQTFLLSEEKGNKFLNIENDE", "length": 918 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A523-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWNDACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGRTKMWDRPMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEEEEKRGSQPLDQVQCVFPDPHVACSSRLVNCCLTSSFCRGLFSSLSTNQSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSSQKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTNQNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNCETKRTLEALQEEKPELTVVFEISW", "length": 1035 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FA88-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "nlrc11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYCNYNMDNTRSSRDEDIYSCTSRESEEVLSNTSYWSLPSYFRHRKFHRSSVHEKISDSSESSRVSLKSDWSMNPPPLLGEERKSSNLNMSSLVSVRSDWSMDPPPLLRAKGKSAVSSGVSDNIDWLVCSPYLRVERKSSALRHKLSLLKKFQCLYEGTAVQGKPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLIKDKKFSLVSLLQTFFTREIHLDMIQNSAVIFIFDGLDECRLPFNFSRNEILLDVTKETSVDVLLTNLIVGNLLPYALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILRLGKLAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLLFTNHNINVFEQMTKSFEGTPLNKSDLQSLTLNMELFEISEPVLTDVAAMCEMDWRVVNEISALHCKAVDEVLQNKNGHLDLFLRFLLGLSVECNQILLQRLTKQRRHLYNDNKTVEYIKKKIRTINSPEKSISLFHCLNELGDHSLVEEIQQYLTSGKIKEFKLSSSQWSAVAFVLLTSEKKLEEFWLKEFVGAETKADHVLQKLLPVVKESRKAELSKCGLTEECCAALASALRSKLSHVRELDLSGNKLGDSGIENLSTGLENLHCKLEILRLRSCGITAKGCTALASALRSNPEQIRQLDLSENNIRDWGVKHLFTELKNPDCKLEILGLRNCGITIEGCAALTSALIINPSHLRELDISRNSLGDTGQELLTSLLNSQHHKLEILLLHKFPMTFTSLPSSHSPEMFPQRFRTHNLKE", "length": 966 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q5R7-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSTARDGLYRLSTYLEELEAGELKKFKLFLGIAEDLSQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGEDLVRVTPNNGLCLFESQSACPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPEPPHTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGPWCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTPRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFAAMYCALNGREAVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWSISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQVVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGSAYSTGMEDDPPEPSGVQTQSTYLQERNMLPDVYSAYLSAAVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISGSACQDLAAAVIANRNLIRLDLSDNSIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLSNNSYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVNTCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGISQTLHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFGMDLNKKTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M918-1", "protein_name": "NLR family, pyrin domain containing 14", "gene_name": "Nlrp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTEDEEMEDQLSKEEIVSEDKEFDYRTIIKENFFIIWDKTSLLGESATLNCVTTHKDQKLLEHIFDVNIQTSKSPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLSGREISQEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFALCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMTCQTSTALFTYYICSLFPRIAGSSVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQDTECENCYTFTHLQVQEYFAALFYLLRENPEEKDHPLEPFENVHLLLESNHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLTISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVKVDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDPTAEICLEDAAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLNSCYDFSFLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQSNRSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTKTKRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNNKSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNNSNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNNQSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCPNTESGCWWQYF", "length": 990 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RA38-1", "protein_name": "NLR family pyrin domain containing 2", "gene_name": "Nlrp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHSDQLGFNLKDVLKKLDKTELNNFKSTLKSCSLPQTMKQISKLTMDLANGAQLAEILTDYCPNDWVKRVTFKILEEINRADLAELVMKQVEEAASKASEEKVSSKPREPLKTSLFPQDFVQGDERPEHKHKKEWRNMYTEKWKKNFWPKCNKEIYVDTESYRTLLTLCNPKIEMPFAYTIVLHGPPGSGKTTMARRLMLEWSESKQAQSFSCAFYISCRKLNNSKPCTFAHLLSMNNPSWRYYMIRRLVLSEQFLFVVDGFDELTFPAGALLRDICGDWNTVKPVEVLLSSLLMRKMEPHSTLLVTTQTQSLHQIYLMVDQPVLVETQGFLEPEKQEYFQQYFEDEEGEEEGEGEGKALRALKEVKCNEALFQMASLPAACGIFCLCLELGMKKGEDLALTCQTYTSMFLNFLCRVFLQEACDGHLNKQLQILFKKICILAADSLLEQVPILCEEDFLKLKLNLNKLHPVVYRCIFLEDSSCTNCLSFICLSIQQLLAAIIFVQELGQESKDVSKYSIQKMLSREARLKNPNLSGVLPFVFSLLNKTHIQELETIFGCQISMGVKRKFLECELGENKPFLLLMDLQEIFSCLYESQEEEFVKEAMALFGEVSLHLKTNMDLVHASFCLKNSQNLQTMFLKVEKAVFPENFATLESTAEDQRFQDKKCMLTLWTDFCDTFHSNEKLAFLEIHESFLNSSSLEILCEKLSSAPCHLQKVVLKNISPDDAYEKLCLIFCGYETISHLTLQGGKLDSMLHSLCKVVKNPACNLKFLSLGSCSTTAQKWDDFFPALKANQSLISLDLTDNNLLDKGVRLLCNTWKQSKCILQRVSLENCHLTEVCCKDLSSVLMVSQTLTHLSLAKNELGDNGVKKLCESLSFPKCKLQTLVLWSCNITSNGCHYLSKMLGQAPSLKHLDLGLNRIGTTGAKFLCEALKSPRSNLKSLWLCGCSIIPTNCKDFSEILRSNKSLNTLDLSQNVMGTDAVKIFCESLKLQICPLQTLRLKFDEANPSIQKLIQEMKESHPQLSITSDQVDPKKKSHSFPHFIF", "length": 1048 }, "evidence": [ { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13489-1", "protein_name": "Ribonuclease inhibitor", "gene_name": "RNH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLDIQSLDIQCEELSDARWAELLPLLQQCQVVRLDDCGLTEARCKDISSALRVNPALAELNLRSNELGDVGVHCVLQGLQTPSCKIQKLSLQNCCLTGAGCGVLSSTLRTLPTLQELHLSDNLLGDAGLQLLCEGLLDPQCRLEKLQLEYCSLSAASCEPLASVLRAKPDFKELTVSNNDINEAGVRVLCQGLKDSPCQLEALKLESCGVTSDNCRDLCGIVASKASLRELALGSNKLGDVGMAELCPGLLHPSSRLRTLWIWECGITAKGCGDLCRVLRAKESLKELSLAGNELGDEGARLLCETLLEPGCQLESLWVKSCSFTAACCSHFSSVLAQNRFLLELQISNNRLEDAGVRELCQGLGQPGSVLRVLWLADCDVSDSSCSSLAATLLANHSLRELDLSNNCLGDAGILQLVESVRQPGCLLEQLVLYDIYWSEEMEDRLQALEKDKPSLRVIS", "length": 461 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59044-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 6", "gene_name": "NLRP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQPEAPCSSTGPRLAVARELLLAALEELSQEQLKRFRHKLRDVGPDGRSIPWGRLERADAVDLAEQLAQFYGPEPALEVARKTLKRADARDVAAQLQERRLQRLGLGSGTLLSVSEYKKKYREHVLQLHARVKERNARSVKITKRFTKLLIAPESAAPEEAMGPAEEPEPGRARRSDTHTFNRLFRRDEEGRRPLTVVLQGPAGIGKTMAAKKILYDWAAGKLYQGQVDFAFFMPCGELLERPGTRSLADLILDQCPDRGAPVPQMLAQPQRLLFILDGADELPALGGPEAAPCTDPFEAASGARVLGGLLSKALLPTALLLVTTRAAAPGRLQGRLCSPQCAEVRGFSDKDKKKYFYKYFRDERRAERAYRFVKENETLFALCFVPFVCWIVCTVLRQQLELGRDLSRTSKTTTSVYLLFITSVLSSAPVADGPRLQGDLRNLCRLAREGVLGRRAQFAEKELEQLELRGSKVQTLFLSKKELPGVLETEVTYQFIDQSFQEFLAALSYLLEDGGVPRTAAGGVGTLLRGDAQPHSHLVLTTRFLFGLLSAERMRDIERHFGCMVSERVKQEALRWVQGQGQGCPGVAPEVTEGAKGLEDTEEPEEEEEGEEPNYPLELLYCLYETQEDAFVRQALCRFPELALQRVRFCRMDVAVLSYCVRCCPAGQALRLISCRLVAAQEKKKKSLGKRLQASLGGGSSSQGTTKQLPASLLHPLFQAMTDPLCHLSSLTLSHCKLPDAVCRDLSEALRAAPALTELGLLHNRLSEAGLRMLSEGLAWPQCRVQTVRVQLPDPQRGLQYLVGMLRQSPALTTLDLSGCQLPAPMVTYLCAVLQHQGCGLQTLSLASVELSEQSLQELQAVKRAKPDLVITHPALDGHPQPPKELISTF", "length": 892 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59045-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 11", "gene_name": "NLRP11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESDSTDFDLLWYLENLSDKEFQSFKKYLARKILDFKLPQFPLIQMTKEELANVLPISYEGQYIWNMLFSIFSMMRKEDLCRKIIGRRNRNQEACKAVMRRKFMLQWESHTFGKFHYKFFRDVSSDVFYILQLAYDSTSYYSANNLNVFLMGERASGKTIVINLAVLRWIKGEMWQNMISYVVHLTAHEINQMTNSSLAELIAKDWPDGQAPIADILSDPKKLLFILEDLDNIRFELNVNESALCSNSTQKVPIPVLLVSLLKRKMAPGCWFLISSRPTRGNNVKTFLKEVDCCTTLQLSNGKREIYFNSFFKDRQRASAALQLVHEDEILVGLCRVAILCWITCTVLKRQMDKGRDFQLCCQTPTDLHAHFLADALTSEAGLTANQYHLGLLKRLCLLAAGGLFLSTLNFSGEDLRCVGFTEADVSVLQAANILLPSNTHKDRYKFIHLNVQEFCTAIAFLMAVPNYLIPSGSREYKEKREQYSDFNQVFTFIFGLLNANRRKILETSFGYQLPMVDSFKWYSVGYMKHLDRDPEKLTHHMPLFYCLYENREEEFVKTIVDALMEVTVYLQSDKDMMVSLYCLDYCCHLRTLKLSVQRIFQNKEPLIRPTASQMKSLVYWREICSLFYTMESLRELHIFDNDLNGISERILSKALEHSSCKLRTLKLSYVSTASGFEDLLKALARNRSLTYLSINCTSISLNMFSLLHDILHEPTCQISHLSLMKCDLRASECEEIASLLISGGSLRKLTLSSNPLRSDGMNILCDALLHPNCTLISLVLVFCCLTENCCSALGRVLLFSPTLRQLDLCVNRLKNYGVLHVTFPLLFPTCQLEELHLSGCFFSSDICQYIAIVIATNEKLRSLEIGSNKIEDAGMQLLCGGLRHPNCMLVNIGLEECMLTSACCRSLASVLTTNKTLERLNLLQNHLGNDGVAKLLESLISPDCVLKVVGLPLTGLNTQTQQLLMTVKERKPSLIFLSETWSLKEGREIGVTPASQPGSIIPNSNLDYMFFKFPRMSAAMRTSNTASRQPL", "length": 1033 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59046-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "NLRP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQSTCLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELKPSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEGEGGAGPDQDVTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSAGAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIANKNLTRMDLSGNGVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC", "length": 1061 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 5", "gene_name": "NLRP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVAGGLELGAAALLSASPRALVTLSTGPTCSILPKNPLFPQNLSSQPCIKMEGDKSLTFSSYGLQWCLYELDKEEFQTFKELLKKKSSESTTCSIPQFEIENANVECLALLLHEYYGASLAWATSISIFENMNLRTLSEKARDDMKRHSPEDPEATMTDQGPSKEKVPGISQAVQQDSATAAETKEQEISQAMEQEGATAAETEEQEISQAMEQEGATAAETEEQGHGGDTWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDSDRWGFRPRTVVLHGKSGIGKSALARRIVLCWAQGGLYQGMFSYVFFLPVREMQRKKESSVTEFISREWPDSQAPVTEIMSRPERLLFIIDGFDDLGSVLNNDTKLCKDWAEKQPPFTLIRSLLRKVLLPESFLIVTVRDVGTEKLKSEVVSPRYLLVRGISGEQRIHLLLERGIGEHQKTQGLRAIMNNRELLDQCQVPAVGSLICVALQLQDVVGESVAPFNQTLTGLHAAFVFHQLTPRGVVRRCLNLEERVVLKRFCRMAVEGVWNRKSVFDGDDLMVQGLGESELRALFHMNILLPDSHCEEYYTFFHLSLQDFCAALYYVLEGLEIEPALCPLYVEKTKRSMELKQAGFHIHSLWMKRFLFGLVSEDVRRPLEVLLGCPVPLGVKQKLLHWVSLLGQQPNATTPGDTLDAFHCLFETQDKEFVRLALNSFQEVWLPINQNLDLIASSFCLQHCPYLRKIRVDVKGIFPRDESAEACPVVPLWMRDKTLIEEQWEDFCSMLGTHPHLRQLDLGSSILTERAMKTLCAKLRHPTCKIQTLMFRNAQITPGVQHLWRIVMANRNLRSLNLGGTHLKEEDVRMACEALKHPKCLLESLRLDCCGLTHACYLKISQILTTSPSLKSLSLAGNKVTDQGVMPLSDALRVSQCALQKLILEDCGITATGCQSLASALVSNRSLTHLCLSNNSLGNEGVNLLCRSMRLPHCSLQRLMLNQCHLDTAGCGFLALALMGNSWLTHLSLSMNPVEDNGVKLLCEVMREPSCHLQDLELVKCHLTAACCESLSCVISRSRHLKSLDLTDNALGDGGVAALCEGLKQKNSVLARLGLKACGLTSDCCEALSLALSCNRHLTSLNLVQNNFSPKGMMKLCSAFACPTSNLQIIGLWKWQYPVQIRKLLEEVQLLKPRVVIDGSWHSFDEDDRYWWKN", "length": 1200 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TKR3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4C", "gene_name": "Nlrp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLRLKQISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRKDLMERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKVQDFSKQKFTQDDYDRFENFLISKVTAKKPHMVFLQGAAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPKTSAPIEDILSQPEKLLFVIDNLEVMECDMSERESELCDTCTEKQPVRILLSSLLRRKMLPKSSFLISATPETFEKMEGRVECTNVKIVTGFNESNIKMYFRSLFQDKTKTQEIFSLVKENQQLFTVCQVPVLCWMVATCLKKEIEKGRDLVSVCRRTTSLYTTHIFNLFIPQSAQYPSKESQAQLQSLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPTLLDVRILEKSKKSEKSYIFLHPSIQEVCAAIFYLLKSHMDHPSQDVKSIEALIFTFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQVDGMKLFYCLFEMDDEAFLAQAMNCMEQINFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNVLSEGQEHSYTEKLLMCWHHMCSVLISSKDIYILQVKNTNLNETASLVLYSHLMYPSCTLKALVVNNVTFLCDNRLFFELIQNQCLQHLDLNLTFLSHGDVKLLCDVLSQEECNIEKLMVAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLVNCSLSEQCWDYLSEVLRRNKTLNHLDISSNDLKDEGLKVLCGALSLPDSVLKSLSVRYCLITTSGCQDLAEVLRKNQNLRNLQVSNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASAFTHCKTLWGINLQENALDHSGLIVLFEALKQQQCTLHVLGLRITDFDKETQELLMAEEEKNPHLSILSSV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X03-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9A", "gene_name": "Nlrp9a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDSSGYGLLQYLQKLSDEEFQRFKEHLRKEPEKFKLKPISWTKIKNTSKEDLVMQLYTHYPGKAWDMVLSLFLQVNREDLSTMAQTERRDKQTKYKEFMKNTFQHIWTMETNTYIPDRSYHEFIEVQYRALQDIFDCESEPVTVVVSGSRGGGKTTFLRKAMLDWASRNLLQNRFQYVFHFSVFSLNNITELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKKLPIQIVLSSLLQKIMLPECSLLLELGNASLSNIIPLLQYPREIIMSGFSEQTIEIYCVSFFNTQTGVEIFKNLKSIKPLFNLCRCPHLCWMICSTIKWQYERREVASRFGRTLGLLYTIFMVSAFKSTYARNPSKQNRARIRTLCTLAVEGMWKQVYVFDSDDLRRNGISESDKKVWLRMKFLQNQGSNIVFYHSTLQWYFAVLFYFLQYKDTRHPVIGNLAQLLGEIYAHKQNQWFHTRILLFGMATEQVNSLLEPCFGCISSKEVRQEIIRYIKSLSQQECNEKLVVHPQNLFFCILDNQEERFVRQLMDRFEEMTVDISDVDDMSATPYCLHRAPKVKNLHLHIQKRVFLEIHDPEYGDLELFKLGQKCSFTTNFGDGLLFCTFLHLPHLKYMNLYGTNLSNDAVERLCSALKFSTCGVEELLLGKCDISSEACGIIAASLINSEVKHLSLVENPLKNKGVMSLCEMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNEHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCYLTSECCEEISAVLTCNTNLKTLKLGNNNIQDTGVKRLCEALCHPNCEMQCLGLDMCDFTSDCCEDLALVLTTCNTLKSLNLDWNAFDHSGLEMLCKALNHKACNLEVLGLDKSLFSEESQTLLQAVEKKNKNLKVLHFPWLKEELEKRGVRLVWNSKN", "length": 949 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X05-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4F", "gene_name": "Nlrp4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFISDFGLIWYLRELNKKEFMKFKDFLIQEILELKLKQVSSTKVKKASREDLANLLLKCGENQAWDMTFRILQKINRKDLTERATGAIVGNPNLYRDHLKKKLTHDCPKKFNVRIQDFIKETFIQNDXDAFENLLISKGTERKPHMVFLKGMAGVGKTLMLKNLMLAWSKGLVFQNKFSYAFYFCCQDVKQLKTASLAELISREWPSPSAPIEEILSQPEKLLFIIDSLEGMEWDLTKQESELCDDCMEKQPVSTLLSSLLRRKMLPESSLLLSTTPETFEKMEDRIQCTDVKTATAFDERSMKIYFHRLFQDRKRAQEAFSLVRENKQLFTICQVPLLCWMVATCLKEEIEKGGDPVSLCRRTTSLYTTHIFSLFIPQSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFGKEALRRNGIFDSDIPTLLDIGMLGKIREFENSYIFLHPSVQEVCAAIFYMLKRHVEHPSQDVKNIETVLFMFLKKVKTQWIFLGCFIFGLLQKSEQEKLGVFFGHRLSKNIHHKLYQCLETLSGNAELQEQIDGMRLFSCLFEMEDEAFLVKAMNCMQQINFVAKNYSDFIVAAYCLKHCSTLKKLSFSTENVLNEGDQSYMEELLICWNNMCSVFVRSKDIQELRIKDTNFNEPAIRVLYESLKYPSFTLNKLVANNVSFGDNHVLFELIQNSSLQYLDLSCSFLSHNEVKLLCDILNQAECNIEKLMIAHCKLSPDDCKIFGSILMSSKSLKVLNLASNNLNQGISSLCKALCHPHCTLEYLVPRSNHCIVNFLLKLSCCGITERGCQDLAEVLKNNQNLKYLHVSYNKLKDTGVMLLCDAIKHPNCHLKDLQLEACEITDASNEELCYAFMQCETLQTLNLMGNAFEVSRMVFFPRKSELMLFIFLHLSRLWITDFDNEFQAFLLSVKKKNHFLTIRGSVEADGEKKGGDSDARTMGELSNEI", "length": 959 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X19-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4E", "gene_name": "Nlrp4e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKELLQQEILQLGLKHISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRQDLMERAGREIAGHSKLYQVHLKKKLTHDYARKFNIKDQDSLKQKFTQDDCDHFENLLISKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPNASAPIEEILSQPEKLLFVIDNLEVMECDMSEWESELCDDCMEKQPVNILMSSLLRRKMLPESSFLVSATPETFEKIEDRIECTNVKMMAGFNESSIKVYFYSLFQDRNRTQEIFSLVRENEQLFSVCQVPVLCWMVATCLKKEIEKGRDPVSICRRITSLYTTYIFNLFIPHSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFAEEALRRNGIMDSDISTLLDVRILEKSKESEKSYIFLHPSIQEVCAAIFHLLKSHVDHPSQDVKSIEALIFTFLKKVKIQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNKELQEQIDGMKLFYCLFEMDDEAFLPQVMNCMEQIKFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNILSEGQEHSYTEKLLICWHHVCSVLTSSKDIHVLQVKDTNFNERAFLVLYSHLKYPSCILKVLEVNNVTLLCDNRLLFELIQNQRLQLLNLSLTFLSHNDVKLLCDVLNQAECNIEKLMVADCNLSPDDCKVFVSVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLAKCSLSEECWHYLSEVLRRNKTLTHLDISFNDLKDEGLKVLCGALTLPDSVLISLSVRYCLITTSGCQDLAEVLRNNQNLRNLQISNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASSFTHCKTLLGINLQENALDHSGLVALFEAMKQQQCTVNLRGLRITDFDKETQEFLMAEKEKNPYLSI", "length": 978 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X22-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9B", "gene_name": "Nlrp9b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSSGYGLLKLLQKLSDEEFQRFKELLREEPEKFKLKPISWTKIENSSKESLVTLLNTHYPGQAWNMMLSLFLQVNREDLSIMAQKKKRHKQTKYKKFMKTTFERIWTLETNTHIPDRNYHLIVEVQYKALQEIFDSESEPVTAIVAGTTGEGKTTFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKRLPTQIVLSSLLQKIMLPGCSLLLELGQISVPKIRHLLKYPRVITMQGFSERSVEFYCMSFFDNQRGIEVAENLRNNEVLHLCSNPYLCWMFCSCLKWQFDREEEGYFKAKTDAAFFTNFMVSAFKSTYAHSPSKQNRARLKTLCTLAVEGMWKELFVFDSEDLRRNGISESDKAVWLKMQFLQTHGNHTVFYHPTLQSYFAAMFYFLKQDKDICVPVIGSIPQLLGNMYARGQTQWLQLGTFLFGLINEQVAALLQPCFGFIQPIYVRQEIICYFKCLGQQECNEKLERSQTLFSCLRDSQEERFVRQVVDLLEEITVDISSSDVLSVTAYALQKSSKLKKLHLHIQKTVFSEIYCPDHCKTRTSIGKRRNTAEYWKTLCGIFCNLYVLDLDSCQFNKRAIQDLCNSMSPTPTVPLTAFKLQSLSCSFMADFGDGSLFHTLLQLPHLKYLNLYGTYLSMDVTEKLCAALRCSACRVEELLLGKCGISSKACGIIAISLINSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLQSLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCFLTSQCCEEISAVLICNRNLKTLKLGNNNIQDTGVRQLCEALSHPNCNLECLGLDLCEFTSDCCKDLALALTTCKTLNSLNLDWKTLDHSGLVVLCEALNHKRCNLKMLGLDKSAFSEESQTLLQDVEKKNNNLNILHHPWFEAERNKRGTRLVWNSRN", "length": 1003 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6B966-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "Nlrp14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTEDDEMEYEASKEETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITPKDQNLLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLNGKEISQVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFALCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVGCVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQDTEYENCYMFTHLHVQEFFAALFYLLRENLEEQDYPSEPFENLYLLLESNHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVRVDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLDTAEMCLEGAAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLNGCQDFTFLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTKSKRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHNRSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNNSNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNNKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECPNTESGCWWNYF", "length": 993 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTR0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9", "gene_name": "NLRP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESFFSDFGLLWYLKELRKEEFWKFKELLKQPLEKFELKPIPWAELKKASKEDVAKLLDKHYPGKQAWEVTLNLFLQINRKDLWTKAQEEMRNKLNPYRKHMKETFQLIWEKETCLHVPEHFYKETMKNEYKELNDAYTAAARRHTVVLEGPDGIGKTTLLRKVMLDWAEGNLWKDRFTFVFFLNVCEMNGIAETSLLELLSRDWPESSEKIEDIFSQPERILFIMDGFEQLKFNLQLKADLSDDWRQRQPMPIILSSLLQKKMLPESSLLIALGKLAMQKHYFMLRHPKLIKLLGFSESEKKSYFSYFFGEKSKALKVFNFVRDNGPLFILCHNPFTCWLVCTCVKQRLERGEDLEINSQNTTYLYASFLTTVFKAGSQSFPPKVNRARLKSLCALAAEGIWTYTFVFSHGDLRRNGLSESEGVMWVGMRLLQRRGDCFAFMHLCIQEFCAAMFYLLKRPKDDPNPAIGSITQLVRASVVQPQTLLTQVGIFMFGISTEEIVSMLETSFGFPLSKDLKQEITQCLESLSQCEADREAIAFQELFIGLFETQEKEFVTKVMNFFEEVFIYIGNIEHLVIASFCLKHCQHLTTLRMCVENIFPDDSGCISDYNEKLVYWRELCSMFITNKNFQILDMENTSLDDPSLAILCKALAQPVCKLRKLIFTSVYFGHDSELFKAVLHNPHLKLLSLYGTSLSQSDIRHLCETLKHPMCKIEELILGKCDISSEVCEDIASVLACNSKLKHLSLVENPLRDEGMTLLCEALKHSHCALERLMLMYCCLTSVSCDSISEVLLCSKSLSLLDLGSNALEDNGVASLCAALKHPGCSIRELWLMGCFLTSDSCKDIAAVLICNGKLKTLKLGHNEIGDTGVRQLCAALQHPHCKLECLGLQTCPITRACCDDIAAALIACKTLRSLNLDWIALDADAVVVLCEALSHPDCALQMLGLHKSGFDEETQKILMSVEEKIPHLTISHGPWIDEEYKIRGVLL", "length": 991 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W24-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "NLRP14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSSSSSFFPDFGLLLYLEELNKEELNTFKLFLKETMEPEHGLTPWNEVKKARREDLANLMKKYYPGEKAWSVSLKIFGKMNLKDLCERAKEEINWSAQTIGPDDAKAGETQEDQEAVLGDGTEYRNRIKEKFCITWDKKSLAGKPEDFHHGIAEKDRKLLEHLFDVDVKTGAQPQIVVLQGAAGVGKTTLVRKAMLDWAEGSLYQQRFKYVFYLNGREINQLKERSFAQLISKDWPSTEGPIEEIMYQPSSLLFIIDSFDELNFAFEEPEFALCEDWTQEHPVSFLMSSLLRKVMLPEASLLVTTRLTTSKRLKQLLKNHHYVELLGMSEDAREEYIYQFFEDKRWAMKVFSSLKSNEMLFSMCQVPLVCWAACTCLKQQMEKGGDVTLTCQTTTALFTCYISSLFTPVDGGSPSLPNQAQLRRLCQVAAKGIWTMTYVFYRENLRRLGLTQSDVSSFMDSNIIQKDAEYENCYVFTHLHVQEFFAAMFYMLKGSWEAGNPSCQPFEDLKSLLQSTSYKDPHLTQMKCFLFGLLNEDRVKQLERTFNCKMSLKIKSKLLQCMEVLGNSDYSPSQLGFLELFHCLYETQDKAFISQAMRCFPKVAINICEKIHLLVSSFCLKHCRCLRTIRLSVTVVFEKKILKTSLPTNTWDGDRITHCWQDLCSVLHTNEHLRELDLYHSNLDKSAMNILHHELRHPNCKLQKLLLKFITFPDGCQDISTSLIHNKNLMHLDLKGSDIGDNGVKSLCEALKHPECKLQTLRLESCNLTVFCCLNISNALIRSQSLIFLNLSTNNLLDDGVQLLCEALRHPKCYLERLSLESCGLTEAGCEYLSLALISNKRLTHLCLADNVLGDGGVKLMSDALQHAQCTLKSLVLRRCHFTSLSSEYLSTSLLHNKSLTHLDLGSNWLQDNGVKLLCDVFRHPSCNLQDLELMGCVLTNACCLDLASVILNNPNLRSLDLGNNDLQDDGVKILCDALRYPNCNIQRLGLEYCGLTSLCCQDLSSALICNKRLIKMNLTQNTLGYEGIVKLYKVLKSPKCKLQVLGLCKEAFDEEAQKLLEAVGVSNPHLIIKPDCNYHNEEDVSWWWCF", "length": 1093 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W25-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 13", "gene_name": "NLRP13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFSVITCPNGGTNQGLLPYLMALDQYQLEEFKLCLEPQQLMDFWSAPQGHFPRIPWANLRAADPLNLSFLLDEHFPKGQAWKVVLGIFQTMNLTSLCEKVRAEMKENVQTQELQDPTQEDLEMLEAAAGNMQTQGCQDPNQEELDELEEETGNVQAQGCQDPNQEEPEMLEEADHRRKYRENMKAELLETWDNISWPKDHVYIRNTSKDEHEELQRLLDPNRTRAQAQTIVLVGRAGVGKTTLAMQAMLHWANGVLFQQRFSYVFYLSCHKIRYMKETTFAELISLDWPDFDAPIEEFMSQPEKLLFIIDGFEEIIISESRSESLDDGSPCTDWYQELPVTKILHSLLKKELVPLATLLITIKTWFVRDLKASLVNPCFVQITGFTGDDLRVYFMRHFDDSSEVEKILQQLRKNETLFHSCSAPMVCWTVCSCLKQPKVRYYDLQSITQTTTSLYAYFFSNLFSTAEVDLADDSWPGQWRALCSLAIEGLWSMNFTFNKEDTEIEGLEVPFIDSLYEFNILQKINDCGGCTTFTHLSFQEFFAAMSFVLEEPREFPPHSTKPQEMKMLLQHVLLDKEAYWTPVVLFFFGLLNKNIARELEDTLHCKISPRVMEELLKWGEELGKAESASLQFHILRLFHCLHESQEEDFTKKMLGRIFEVDLNILEDEELQASSFCLKHCKRLNKLRLSVSSHILERDLEILETSKFDSRMHAWNSICSTLVTNENLHELDLSNSKLHASSVKGLCLALKNPRCKVQKLTCKSVTPEWVLQDLIIALQGNSKLTHLNFSSNKLGMTVPLILKALRHSACNLKYLCLEKCNLSAASCQDLALFLTSIQHVTRLCLGFNRLQDDGIKLLCAALTHPKCALERLELWFCQLAAPACKHLSDALLQNRSLTHLNLSKNSLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTREGCGELANALSHNHNVKILDLGENDLQDDGVKLLCEALKPHRALHTLGLAKCNLTTACCQHLFSVLSSSKSLVNLNLLGNELDTDGVKMLCKALKKSTCRLQKLG", "length": 1043 }, "evidence": [ { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W26-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 10", "gene_name": "NLRP10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMAKARKPREALLWALSDLEENDFKKLKFYLRDMTLSEGQPPLARGELEGLIPVDLAELLISKYGEKEAVKVVLKGLKVMNLLELVDQLSHICLHDYREVYREHVRCLEEWQEAGVNGRYNQVLLVAKPSSESPESLACPFPEQELESVTVEALFDSGEKPSLAPSLVVLQGSAGTGKTTLARKMVLDWATGTLYPGRFDYVFYVSCKEVVLLLESKLEQLLFWCCGDNQAPVTEILRQPERLLFILDGFDELQRPFEEKLKKRGLSPKESLLHLLIRRHTLPTCSLLITTRPLALRNLEPLLKQARHVHILGFSEEERARYFSSYFTDEKQADRAFDIVQKNDILYKACQVPGICWVVCSWLQGQMERGKVVLETPRNSTDIFMAYVSTFLPPDDDGGCSELSRHRVLRSLCSLAAEGIQHQRFLFEEAELRKHNLDGPRLAAFLSSNDYQLGLAIKKFYSFRHISFQDFFHAMSYLVKEDQSRLGKESRREVQRLLEVKEQEGNDEMTLTMQFLLDISKKDSFSNLELKFCFRISPCLAQDLKHFKEQMESMKHNRTWDLEFSLYEAKIKNLVKGIQMNNVSFKIKHSNEKKSQSQNLFSVKSSLSHGPKEEQKCPSVHGQKEGKDNIAGTQKEASTGKGRGTEETPKNTYI", "length": 655 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W28-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 8", "gene_name": "NLRP8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDVNPPSDTPIPFSSSSTHSSHIPPWTFSCYPGSPCENGVMLYMRNVSHEELQRFKQLLLTELSTGTMPITWDQVETASWAEVVHLLIERFPGRRAWDVTSNIFAIMNCDKMCVVVRREINAILPTLEPEDLNVGETQVNLEEGESGKIRRYKSNVMEKFFPIWDITTWPGNQRDFFYQGVHRHEEYLPCLLLPKRPQGRQPKTVAIQGAPGIGKTILAKKVMFEWARNKFYAHKRWCAFYFHCQEVNQTTDQSFSELIEQKWPGSQDLVSKIMSKPDQLLLLLDGFEELTSTLIDRLEDLSEDWRQKLPGSVLLSSLLSKTMLPEATLLIMIRFTSWQTCKPLLKCPSLVTLPGFNTMEKIKYFQMYFGHTEEGDQVLSFAMENTILFSMCRVPVVCWMVCSGLKQQMERGNNLTQSCPNATSVFVRYISSLFPTRAENFSRKIHQAQLEGLCHLAADSMWHRKWVLGKEDLEEAKLDQTGVTAFLGMSILRRIAGEEDHYVFTLVTFQEFFAALFYVLCFPQRLKNFHVLSHVNIQRLIASPRGSKSYLSHMGLFLFGFLNEACASAVEQSFQCKVSFGNKRKLLKVIPLLHKCDPPSPGSGVPQLFYCLHEIREEAFVSQALNDYHKVVLRIGNNKEVQVSAFCLKRCQYLHEVELTVTLNFMNVWKLSSSSHPGSEAPESNGLHRWWQDLCSVFATNDKLEVLTMTNSVLGPPFLKALAAALRHPQCKLQKLLLRRVNSTMLNQDLIGVLTGNQHLRYLEIQHVEVESKAVKLLCRVLRSPRCRLQCLRLEDCLATPRIWTDLGNNLQGNGHLKTLILRKNSLENCGAYYLSVAQLERLSIENCNLTQLTCESLASCLRQSKMLTHLSLAENALKDEGAKHIWNALPHLRCPLQRLVLRKCDLTFNCCQDMISALCKNKTLKSLDLSFNSLKDDGVILLCEALKNPDCTLQILELENCLFTSICCQAMASMLRKNQHLRHLDLSKNAIGVYGILTLCEAFSSQKKREEVIFCIPAWTRITSFSPTPHPPDFTGKSDCLSQINP", "length": 1048 }, "evidence": [ { "id": "HGNC:22940", "url": "https://alliancegenome.org/gene/HGNC:22940#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BU40-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4A", "gene_name": "Nlrp4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEVLQLGLKQVSWTEVKKASRQDLASLLLKHYEEKPAWDMTFRFFQKINRKDLIERAKREIDGCPKLYRAHMKTKMTHDSSRAFTISIQNFLKEKFTEDDYDCFENLFQSKGTESKPQVVFLSGGAGVGKTLMLKRLMLAWIESPVFLHKFSYIFYFCCREVKQLKTASLAELISREWPGPSAPIEEILSKPEKLLFIIDSLEGMECDLFKWESELCDNCTEKQPVNVLLSSLLRRKMLPESSLLISATPESFEKMENRIEYTHVKIIKGLKERNIKMSFHRLFQDRNRAHEAFSLVRENEQLFTVCQVPVLCWMVATCLKEEIEKGRDPVSICRCTTSLYTTHIFNLFIPQNAHSPSKKSQDQLQGLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPILLDIGMLINIRESEKSYIFLHPSVQEVCAAIFYLLKSHVDHPSQEVKSIEKLMFAFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQIDGMKLFYCLFEMDDDTFLVEAMNCMEQINFVAKDYSDVIVAAHCLKHCFTLKKLSFSTQNVLSGAQEHSYMERLLTAWNHICSVFIISKDIQELRMKDTNLSESAFSVLYNNLKYHNYTLNVLVANNVFFVCEKYLFFELIQNCNLQHLNLSLTILSHSDVKLLCDVLSQAECNIEELVVAACSISSDDCKVFASVLISNKTLKHLNLASNTLDKGIASLCKSLCHPDCILEHLVLANCSLNEKCWDYLSEVLRRNKTLSHLDISSNDLKDEGLKVLCRALTLPDSVLKSLSLRHCLITISGCQDLAEVLRNNQNLVSLQVSNNKLEDTGVKLLCDAIKHPNCHLEDLGLEACELTGACCEDLASTFTQCKTLWAMNLLKNALDYNGLVVLCEALKQQTCATYVLGLQITDFDTETQAFLVAEQEKNPCLRILSSL", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C6J9-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4B", "gene_name": "Nlrp4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLFSDFGFIWYWKELNKIEFMYFKELLIHEILQMGLKQISWTEVKEASREDLAILLVKHCDGNQAWDTTFRVFQMIGRNVITNRATGEIAAHSTIYRAHLKEKLTHDCSRKFNISIQNFFQDEYDHLENLLVPNGTENNPKMVVLQGVAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCHDVKQLQTASLADLISREWPSPSAPMEEILSQPEKLLFIIDSLEGMEWNVTQQDSQLCYNCMEKQPVNVLLSSLLRKKILPESSLLISTSCETFKDLKDWIEYTNVRTITGFKENNINMCFHSLFQDRNIAQEAFSLIRENEQLFTVCQAPVVCYMVATCLKNEIESGKDPVSICRRTTSLYTTHILNLFIPHNAQNPSNNSEDLLDNLCFLAVEGMWTDISVFNEEALRRNGIMDSDIPTLLDIGILEQSRESENSYIFLHPSVQEFCAAMFYLLHSEMDHSCQGVYFIETFLFTFLNKIKKQWVFLGCFFFGLLHETEQEKLEAFFGYHLSKELRRQLFLWLELLLDTLHPDVKKINTMKFFYCLFEMEEEVFVQSAMNCREQIDVVVKGYSDFIVAAYCLSHGSALTDFSISAQNVLNEELGQRGKLLILWHQICSVFLRNKDIKTLRIEDTIFNEPVFKIFYSYLKNSSCILKTLVAYNVSFLCDKRLFLELIQSYNLEELYLRGTFLSHSDVEMLCDILNQAECNIRILDLANCSLCEHSWDYLSDVLRQNKSLRYLNISYNNLKDEGLKALCRALTLPNSALHSLSLEACQLTGACCKDLASTFTRYKCLRRINLAKNSLGFSGLFVLCKAMKDQTCTLYELKLRMADFDSDSQEFLLSEMERNKILSIENGV", "length": 863 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4B8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWNDTCTSHSSMVCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIGRTKMRDSPMSSLKLELLFEPEDGHSEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSDYLQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFFHNSPKEEEEERRGGRPLDQVQCVFPDTHVACSSRLVNCCLTSSFCRGLFSSLSTNRSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSSSQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTNQNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHNHSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNRETKRALEALQEEKPELTIVFEISW", "length": 1033 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WX94-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 7", "gene_name": "NLRP7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTSPQLEWTLQTLLEQLNEDELKSFKSLLWAFPLEDVLQKTPWSEVEEADGKKLAEILVNTSSENWIRNATVNILEEMNLTELCKMAKAEMMEDGQVQEIDNPELGDAEEDSELAKPGEKEGWRNSMEKQSLVWKNTFWQGDIDNFHDDVTLRNQRFIPFLNPRTPRKLTPYTVVLHGPAGVGKTTLAKKCMLDWTDCNLSPTLRYAFYLSCKELSRMGPCSFAELISKDWPELQDDIPSILAQAQRILFVVDGLDELKVPPGALIQDICGDWEKKKPVPVLLGSLLKRKMLPRAALLVTTRPRALRDLQLLAQQPIYVRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQMSVFHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYALEKEEGEDRDGHAWDIGDVQKLLSGEERLKNPDLIQVGHFLFGLANEKRAKELEATFGCRMSPDIKQELLQCKAHLHANKPLSVTDLKEVLGCLYESQEEELAKVVVAPFKEISIHLTNTSEVMHCSFSLKHCQDLQKLSLQVAKGVFLENYMDFELDIEFERCTYLTIPNWARQDLRSLRLWTDFCSLFSSNSNLKFLEVKQSFLSDSSVRILCDHVTRSTCHLQKVEIKNVTPDTAYRDFCLAFIGKKTLTHLTLAGHIEWERTMMLMLCDLLRNHKCNLQYLRLGGHCATPEQWAEFFYVLKANQSLKHLRLSANVLLDEGAMLLYKTMTRPKHFLQMLSLENCRLTEASCKDLAAVLVVSKKLTHLCLAKNPIGDTGVKFLCEGLSYPDCKLQTLVLQQCSITKLGCRYLSEALQEACSLTNLDLSINQIARGLWILCQALENPNCNLKHLRLKTYETNLEIKKLLEEVKEKNPKLTIDCNASGATAPPCCDFFC", "length": 980 }, "evidence": [ { "id": "HGNC:22947", "url": "https://alliancegenome.org/gene/HGNC:22947#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96MN2-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4", "gene_name": "NLRP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQMTLQLELKQIPWTEVKKASREELANLLIKHYEEQQAWNITLRIFQKMDRKDLCMKVMRERTGYTKTYQAHAKQKFSRLWSSKSVTEIHLYFEEEVKQEECDHLDRLFAPKEAGKQPRTVIIQGPQGIGKTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELRELPPTSLADLISREWPDPAAPITEIVSQPERLLFVIDSFEELQGGLNEPDSDLCGDLMEKRPVQVLLSSLLRKKMLPEASLLIAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQLFSICQIPLLCWILCTSLKQEMQKGKDLALTCQSTTSVYSSFVFNLFTPEGAEGPTPQTQHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGERESSYVFLHVCIQEFCAALFYLLKSHLDHPHPAVRCVQELLVANFEKARRAHWIFLGCFLTGLLNKKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFVKQAVNLLQEANFHIIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFKKEDEHSSTSDYSLICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFSGQSVLLFEVLFYQPDLKYLSFTLTKLSRDDIRSLCDALNYPAGNVKELALVNCHLSPIDCEVLAGLLTNNKKLTYLNVSCNQLDTGVPLLCEALCSPDTVLVYLMLAFCHLSEQCCEYISEMLLRNKSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDLASALISNQNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLASVLTCSKTLQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRKTDFDEETQALLTAEEERNPNLTITDDCDTITRVEI", "length": 994 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1561918", "url": "https://alliancegenome.org/gene/RGD:1561918#orthology", "database": "AGR" }, { "id": "RGD:1563529", "url": "https://alliancegenome.org/gene/RGD:1563529#orthology", "database": "AGR" }, { "id": "MGI:3056600", "url": "https://alliancegenome.org/gene/MGI:3056600#orthology", "database": "AGR" }, { "id": "MGI:2443697", "url": "https://alliancegenome.org/gene/MGI:2443697#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:1890518", "url": "https://alliancegenome.org/gene/MGI:1890518#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW", "length": 1036 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-363", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-363#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9C000-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 1", "gene_name": "NLRP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGGAWGRLACYLEFLKKEELKEFQLLLANKAHSRSSSGETPAQPEKTSGMEVASYLVAQYGEQRAWDLALHTWEQMGLRSLCAQAQEGAGHSPSFPYSPSEPHLGSPSQPTSTAVLMPWIHELPAGCTQGSERRVLRQLPDTSGRRWREISASLLYQALPSSPDHESPSQESPNAPTSTAVLGSWGSPPQPSLAPREQEAPGTQWPLDETSGIYYTEIREREREKSEKGRPPWAAVVGTPPQAHTSLQPHHHPWEPSVRESLCSTWPWKNEDFNQKFTQLLLLQRPHPRSQDPLVKRSWPDYVEENRGHLIEIRDLFGPGLDTQEPRIVILQGAAGIGKSTLARQVKEAWGRGQLYGDRFQHVFYFSCRELAQSKVVSLAELIGKDGTATPAPIRQILSRPERLLFILDGVDEPGWVLQEPSSELCLHWSQPQPADALLGSLLGKTILPEASFLITARTTALQNLIPSLEQARWVEVLGFSESSRKEYFYRYFTDERQAIRAFRLVKSNKELWALCLVPWVSWLACTCLMQQMKRKEKLTLTSKTTTTLCLHYLAQALQAQPLGPQLRDLCSLAAEGIWQKKTLFSPDDLRKHGLDGAIISTFLKMGILQEHPIPLSYSFIHLCFQEFFAAMSYVLEDEKGRGKHSNCIIDLEKTLEAYGIHGLFGASTTRFLLGLLSDEGEREMENIFHCRLSQGRNLMQWVPSLQLLLQPHSLESLHCLYETRNKTFLTQVMAHFEEMGMCVETDMELLVCTFCIKFSRHVKKLQLIEGRQHRSTWSPTMVVLFRWVPVTDAYWQILFSVLKVTRNLKELDLSGNSLSHSAVKSLCKTLRRPRCLLETLRLAGCGLTAEDCKDLAFGLRANQTLTELDLSFNVLTDAGAKHLCQRLRQPSCKLQRLQLVSCGLTSDCCQDLASVLSASPSLKELDLQQNNLDDVGVRLLCEGLRHPACKLIRLGLDQTTLSDEMRQELRALEQEKPQLLIFSRRKPSVMTPTEGLDTGEMSNSTSSLKRQRLGSERAASHVAQANLKLLDVSKIFPIAEIAEESSPEVVPVELLCVPSPASQGDLHTKPLGTDDDFWGPTGPVATEVVDKEKNLYRVHFPVAGSYRWPNTGLCFVMREAVTVEIEFCVWDQFLGEINPQHSWMVAGPLLDIKAEPGAVEAVHLPHFVALQGGHVDTSLFQMAHFKEEGMLLEKPARVELHHIVLENPSFSPLGVLLKMIHNALRFIPVTSVVLLYHRVHPEEVTFHLYLIPSDCSIRKAIDDLEMKFQFVRIHKPPPLTPLYMGCRYTVSGSGSGMLEILPKELELCYRSPGEDQLFSEFYVGHLGSGIRLQVKDKKDETLVWEALVKPGDLMPATTLIPPARIAVPSPLDAPQLLHFVDQYREQLIARVTSVEVVLDKLHGQVLSQEQYERVLAENTRPSQMRKLFSLSQSWDRKCKDGLYQALKETHPHLIMELWEKGSKKGLLPLSS", "length": 1473 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DAM1-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Lrrc34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKLQAQYCYLCSENIRKTNPFILNILQKLDEEIEKRPKEKFTVNIAGNNRLDSGQRITGEDFWLLSKTLRNQPCISGVDVRYNLIGDVGAFYAAKLLQKQPSITYLNLMFNDIGPEGGELIAKALHKNKTLKYLRMTGNKIENTGGMLFAAMLQMNSSLEKLDLGDCDLGLQCVIAFSTVLTQNQAIKGINLNRPILYGEQEESTVHIGHMLKENHVLVELHMCKHGMKNYGLQQLCNALYLNSSLRYLDVSCNKITRDGMVFLADVLKSNTTLEVLDLSFNRIETAGAKYLSETLTSHNRSLKALSVVSNKIEGEGLVALSQSMKTNLVLSNIYIWGNKFDEDTCVAYSDLIKSGRLKPDNTDVEPYMVDEHIYLSEVSNGLKRHYYWAPTYGETYMPSSSAGFALVPVGEHL", "length": 415 }, "evidence": [ { "id": "FB:FBgn0033369", "url": "https://alliancegenome.org/gene/FB:FBgn0033369#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NX02-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 2", "gene_name": "NLRP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": 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"type": "synonym", "evidence": [ { "id": "XP_021328008", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328008" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328008", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328008" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLU5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438863", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU5", "locus": {} } ], "crossref": [ { "id": "A0A8M9PLU5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PLU5", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438863", "url": "https://www.ncbi.nlm.nih.gov/gene/110438863", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001940", "url": 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"pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLU5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLU5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU5" } ], "pmid": "" }, { "name": "positive regulation of apoptotic process", "id": "GO:0043065", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043065", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLU5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU5" } ], "pmid": "" }, { "name": "programmed cell death", "id": "GO:0012501", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012501", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLU5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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HTRA2, mitochondrial isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328013" }, "gene_names": [ { "name": "si:dkey-10b15.8", "type": "recommended", "evidence": [ { "id": "A0A8M9PLU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU9" } ] }, { "name": "si:dkey-10b15.8", "type": "synonym", "evidence": [ { "id": "XP_021328013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328013" } ] } ], "protein_names": [ { "name": "Serine protease HTRA2, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PLU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU9/entry#names_and_taxonomy" } ] }, { "name": "serine protease HTRA2, mitochondrial isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021328013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328013" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328013" } ] } ], "disease": [ { "disease_id": "DOID:0070000", "recommended_name": { "id": "DOID:0070000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070000", "name": "3-methylglutaconic aciduria type 8", "description": "A 3-methylglutaconic aciduria that has_material_basis_in homozygous mutation in the HTRA2 gene on chromosome 2p13." }, "synonyms": [ { "id": "DOID:0070000", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070000", "name": "3-methylglutaconic aciduria type VIII, MGCA8", "description": "" }, { "id": "MONDO:0044723", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0044723", "name": "3-methylglutaconic aciduria type 8", "description": "" }, { "id": "MONDO:0044723", "resource": "MONDO", "url": 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"resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate cancer", "description": "A male reproductive organ cancer that is located_in the prostate." }, "synonyms": [ { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "NGP - new growth of prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "hereditary prostate cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "malignant tumor of the prostate", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate cancer, familial", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostate neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostatic cancer", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "prostatic neoplasm", "description": "" }, { "id": "DOID:10283", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10283", "name": "tumor of the prostate", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, hereditary, X-linked 1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "HPCX1", "description": "" }, { "id": "MONDO:0010257", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010257", "name": "prostate cancer, 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"MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "familial prostate cancer caused by mutation in RNASEL", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "prostate cancer, hereditary, type 1", "description": "" }, { "id": "MONDO:0011098", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011098", "name": "HPC1", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "prostate cancer, hereditary, type 8", "description": "" }, { "id": "MONDO:0011270", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011270", "name": "HPC8", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, 3", "description": "" }, { "id": "MONDO:0012093", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012093", "name": "prostate cancer, hereditary, type 3", 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6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "prostate cancer, hereditary, type 6", "description": "" }, { "id": "MONDO:0012300", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012300", "name": "HPC6", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "HPC7", "description": "" }, { "id": "MONDO:0012470", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012470", "name": "prostate cancer, hereditary, 7", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "prostate cancer, hereditary, type 9", "description": "" }, { "id": "MONDO:0012597", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012597", "name": "HPC9", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "HPC10", "description": "" }, { "id": "MONDO:0012620", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012620", "name": "prostate cancer, hereditary, 10", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the EHBP1 gene." }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "EHBP1 familial prostate cancer", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "familial prostate cancer caused by mutation in EHBP1", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "prostate cancer, hereditary, type 12", "description": "" }, { "id": "MONDO:0012741", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012741", "name": "HPC12", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "Any familial prostate cancer in which the cause of the disease is a mutation in the MSMB gene." }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "MSMB familial prostate cancer", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "familial prostate cancer caused by mutation in MSMB", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "prostate cancer, hereditary, type 13", "description": "" }, { "id": "MONDO:0012758", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012758", "name": "HPC13", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "HPC11", "description": "" }, { "id": "MONDO:0012768", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012768", "name": "prostate cancer, hereditary, 11", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "HPC14", "description": "" }, { "id": "MONDO:0012769", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012769", "name": "prostate cancer, hereditary, 14", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "HPC15", "description": "" }, { "id": "MONDO:0012770", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012770", "name": "prostate cancer, hereditary, 15", "description": "" }, { "id": "MONDO:0700275", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0700275", "name": "prostate cancer, hereditary", "description": "An instance of prostate cancer that is caused by an inherited genomic modification in an individual. Familial prostate cancer (FPC) is a malignant tumor of the prostate with an early onset. FPC is either asymptomatic or causes mictionary symptoms, erectile dysfunction, bone pain, venous compression and infectious or inflammatory syndrome (for the metastatic forms). It is also characterized by familial antecedents." }, { "id": "MIM:601518", "resource": "MIM", "url": "https://www.omim.org/entry/601518", "name": "Prostate cancer, hereditary, 1", "description": "Prostate cancer, hereditary, 1" }, { "id": "MIM:610997", "resource": "MIM", "url": "https://www.omim.org/entry/610997", "name": "Prostate cancer, hereditary, 9", "description": "Prostate cancer, hereditary, 9" }, { "id": "MIM:611868", "resource": "MIM", "url": "https://www.omim.org/entry/611868", "name": "Prostate cancer, hereditary, 12", "description": "Prostate cancer, hereditary, 12" }, { "id": "MIM:611928", "resource": "MIM", "url": "https://www.omim.org/entry/611928", "name": "Prostate cancer, hereditary, 13", "description": "Prostate cancer, hereditary, 13" }, { "id": "MIM:611955", "resource": "MIM", "url": "https://www.omim.org/entry/611955", "name": "Prostate cancer, hereditary, 11", "description": "Prostate cancer, hereditary, 11" }, { "id": "MIM:176807", "resource": "MIM", "url": "https://www.omim.org/entry/176807", "name": "Prostate cancer", "description": "Prostate cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10283", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10283" } ] }, { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "GC", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] }, { "disease_id": "DOID:10652", "recommended_name": { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid." }, "synonyms": [ { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer disease", "description": "" }, { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimers dementia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ] }, { "disease_id": "DOID:11088", "recommended_name": { "id": "DOID:11088", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11088", "name": "asphyxia neonatorum", "description": "A respiratory system disease that is characterized by deprivation of oxygen to a newborn infant that lasts long enough during the birth process to cause physical harm, usually to the brain." }, "synonyms": [ { "id": "DOID:11088", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11088", "name": "Asphyxia - birth", "description": "" }, { "id": "DOID:11088", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11088", "name": "Asphyxia, in liveborn infant", "description": "" }, { "id": "DOID:11088", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11088", "name": "Birth asphyxia", "description": "" }, { "id": "DOID:11088", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11088", "name": "postnatal asphyxia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "11088", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11088" } ] }, { "disease_id": "DOID:11383", "recommended_name": { "id": "DOID:11383", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11383", "name": "cryptorchidism", "description": "" }, "synonyms": [ { "id": "DOID:11383", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11383", "name": "Cryptorchism", "description": "" }, { "id": "DOID:11383", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11383", "name": "Undescended testicle", "description": "" }, { "id": "DOID:11383", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11383", "name": "Undescended testis", "description": "" }, { "id": "DOID:11383", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11383", "name": "undescended testicles", "description": "" }, { "id": "MONDO:0009047", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009047", "name": "cryptorchidism", "description": "The failure of one or both testes of a male fetus to descend from the abdomen into the scrotum during the late part of pregnancy. If not surgically corrected in early childhood, males may be at increased risk for testicular cancer later in life." }, { "id": "MONDO:0009047", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009047", "name": "cryptorchidism", "description": "" }, { "id": "MONDO:0009047", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009047", "name": "cryptorchidism (disease)", "description": "" }, { "id": "MONDO:0009047", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009047", "name": "undescended testes", "description": "" }, { "id": "MONDO:0009047", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009047", "name": "undescended testicle", "description": "" }, { "id": "MONDO:0009047", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009047", "name": "undescended testis", "description": "" }, { "id": "MIM:219050", "resource": "MIM", "url": "https://www.omim.org/entry/219050", "name": "Cryptorchidism", "description": "Cryptorchidism" } ], "unlinked_id_list": [], "evidence": [ { "id": "11383", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11383" } ] }, { "disease_id": "DOID:1380", "recommended_name": { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "endometrial cancer", "description": "A uterine cancer that is located_in tissues lining the uterus." }, "synonyms": [ { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "endometrial Ca", "description": "" }, { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "endometrial neoplasm", "description": "" }, { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "malignant endometrial neoplasm", "description": "" }, { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "malignant neoplasm of endometrium", "description": "" }, { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "neoplasm of endometrium", "description": "" }, { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "primary malignant neoplasm of endometrium", "description": "" }, { "id": "DOID:1380", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1380", "name": "tumor of Endometrium", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrial cancer", "description": "Primary or metastatic malignant neoplasm involving the endometrium (mucous membrane that lines the endometrial cavity)." }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrial neoplasm", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "neoplasm of endometrium", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "tumor of endometrium", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "tumour of endometrium", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "cancer of endometrium", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrial cancer", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrial cancer, familial, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrial cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrial carcinoma, somatic", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "endometrium cancer", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "malignant endometrial neoplasm", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "malignant endometrium neoplasm", "description": "" }, { "id": "MONDO:0011962", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011962", "name": "malignant neoplasm of endometrium", "description": "" }, { "id": "MIM:608089", "resource": "MIM", "url": "https://www.omim.org/entry/608089", "name": "Endometrial cancer", "description": "Endometrial cancer" } ], "unlinked_id_list": [ "DOID:5166" ], "evidence": [ { "id": "1380", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1380" } ] }, { "disease_id": "DOID:14330", "recommended_name": { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "Parkinson's disease", "description": "A synucleinopathy that has_material_basis_in degeneration of the central nervous system that often impairs motor skills, speech, and other functions." }, "synonyms": [ { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "Parkinson disease", "description": "" }, { "id": "DOID:14330", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14330", "name": "paralysis agitans", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "late-onset Parkinson disease", "description": "A Parkinson disease that begins after around the age of 50." }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "LOPD", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "PARK", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "PD", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, age of onset, modifier, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, late-onset", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, late-onset, susceptibility to, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "Parkinson disease, susceptibility to, Multifactorial", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "autosomal dominant late-onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "hereditary late onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "hereditary late-onset Parkinson disease", "description": "" }, { "id": "MONDO:0008199", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008199", "name": "late-onset Parkinson disease", "description": "" }, { "id": "MIM:168600", "resource": "MIM", "url": "https://www.omim.org/entry/168600", "name": "Parkinson disease", "description": "Parkinson disease" } ], "unlinked_id_list": [], "evidence": [ { "id": "14330", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14330" } ] }, { "disease_id": "DOID:1824", "recommended_name": { "id": "DOID:1824", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1824", "name": "status epilepticus", "description": "" }, "synonyms": [ { "id": "DOID:1824", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1824", "name": "Grand mal status", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1824", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1824" } ] }, { "disease_id": "DOID:224", "recommended_name": { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death." }, "synonyms": [ { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "TIA", "description": "" }, { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "TIA - Transient ischaemic attack", "description": "" }, { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "Transient cerebral ischaemia", "description": "" }, { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "Transient ischemic attacks", "description": "" }, { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "transient ischemic attack", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ] }, { "disease_id": "DOID:231", "recommended_name": { "id": "DOID:231", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:231", "name": "motor neuron disease", "description": "A neurodegenerative disease that is located_in the motor neurons." }, "synonyms": [], "unlinked_id_list": [ "DOID:681" ], "evidence": [ { "id": "231", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:231" } ] }, { "disease_id": "DOID:2394", "recommended_name": { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "ovarian cancer", "description": "A female reproductive organ cancer that is located_in the ovary." }, "synonyms": [ { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "malignant Ovarian tumor", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "malignant tumour of ovary", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "ovarian neoplasm", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "ovary neoplasm", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "primary ovarian cancer", "description": "" }, { "id": "DOID:2394", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2394", "name": "tumor of the Ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian cancer", "description": "A primary or metastatic malignant neoplasm involving the ovary. Most primary malignant ovarian neoplasms are either carcinomas (serous, mucinous, or endometrioid adenocarcinomas) or malignant germ cell tumors. Metastatic malignant neoplasms to the ovary include carcinomas, lymphomas, and melanomas." }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovary neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "tumor of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "tumour of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "cancer of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "cancer of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant neoplasm of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant neoplasm of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant ovarian neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant ovarian tumor", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant ovarian tumour", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant ovary neoplasm", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumor of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumor of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumour of ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "malignant tumour of the ovary", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian cancer", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian cancer, somatic", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian malignant tumor", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovarian malignant tumour", "description": "" }, { "id": "MONDO:0008170", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008170", "name": "ovary cancer", "description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "ovarian cancer, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "OVCAS1", "description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "ovarian cancer, susceptibility to", "description": "" }, { "id": "MONDO:0011931", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011931", "name": "ovarian cancer, susceptibility to, 1", "description": "" }, { "id": "MIM:167000", "resource": "MIM", "url": "https://www.omim.org/entry/167000", "name": "Ovarian cancer", "description": "Ovarian cancer" } ], "unlinked_id_list": [ "DOID:2151" ], "evidence": [ { "id": "2394", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2394" } ] }, { "disease_id": "DOID:3525", "recommended_name": { "id": "DOID:3525", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3525", "name": "middle cerebral artery infarction", "description": "" }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "3525", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3525" } ] }, { "disease_id": "DOID:9256", "recommended_name": { "id": "DOID:9256", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9256", "name": "colorectal cancer", "description": "A large intestine cancer that is located_in the colon and/or located_in the rectum." }, "synonyms": [ { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "A primary or metastatic malignant neoplasm that affects the colon or rectum. Representative examples include carcinoma, lymphoma, and sarcoma." }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "cancer of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, advanced, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colon cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer with chromosomal instability, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, somatic", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectal cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "colorectum cancer", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectal tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant colorectum neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large bowel tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine neoplasm", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumor", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant large intestine tumour", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of colorectum", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant neoplasm of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumor of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large bowel", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "malignant tumour of the large intestine", "description": "" }, { "id": "MONDO:0005575", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005575", "name": "CRC", "description": "" }, { "id": "MIM:114500", "resource": "MIM", "url": "https://www.omim.org/entry/114500", "name": "Colorectal cancer", "description": "Colorectal cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "9256", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9256" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-10b15.8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141212-238", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-238", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PLU9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PLU9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06785", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06785", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "560031", "url": "https://www.ncbi.nlm.nih.gov/gene/560031", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041489", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041489", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:560031", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560031", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR22939", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22939", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22939:SF127", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22939:SF127", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13365", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13365", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17820", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17820", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021328013", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328013", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GN23", "url": "https://www.uniprot.org/uniprotkb/A0AC58GN23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GN23-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GN23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-141212-238", "url": "https://zfin.org/ZDB-GENE-141212-238", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGSPFSLKNTITSGIVSSAQRDSKELGLSNSNKDYIQTDATIDFGNSGGPLINLDGEVIGINTMKVTAGISFAIPSDRVSLFLDRSADKQKSWFGESGSKRRYIEVMMLTLTPSIIDELRMRDPSFPDVSHGVLIHRVIVGSPANRAGMKPGEVIIEINGVKVNTSEEIYNAVRTSESLNVVVRRGADLLMLHMTPESTERHQVKYLVRLRNGEL", "length": 215, "header": "tr|A0A8M9PLU9-1|A0A8M9PLU9_DANRE Isoform 1 of Serine protease HTRA2, mitochondrial isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-10b15.8 PE=3 SV=1 CANONICAL=A0A8M9PLU9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLU9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU9/entry#A0A8M9PLU9-1", "sequence": { "sequence": "MGSPFSLKNTITSGIVSSAQRDSKELGLSNSNKDYIQTDATIDFGNSGGPLINLDGEVIGINTMKVTAGISFAIPSDRVSLFLDRSADKQKSWFGESGSKRRYIEVMMLTLTPSIIDELRMRDPSFPDVSHGVLIHRVIVGSPANRAGMKPGEVIIEINGVKVNTSEEIYNAVRTSESLNVVVRRGADLLMLHMTPESTERHQVKYLVRLRNGEL", "length": 215, "header": "tr|A0A8M9PLU9-1|A0A8M9PLU9_DANRE Isoform 1 of Serine protease HTRA2, mitochondrial isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-10b15.8 PE=3 SV=1 CANONICAL=A0A8M9PLU9-1" }, "locus": {} }, { "isoform_ac": "A0AC58GN23-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU9/entry#A0AC58GN23-1", "sequence": { "sequence": "MVKSRFATRLLLKKEAVPVRVDCPVSTHLDGEVIGINTMKVTAGISFAIPSDRVSLFLDRSADKQKSWFGESGSKRRYIEVMMLTLTPSIIDELRMRDPSFPDVSHGVLIHRVIVGSPANRAGMKPGEVIIEINGVKVNTSEEIYNAVRTSESLNVVVRRGADLLMLHMTPESTERHQVKYLVRLRNGEL", "length": 190, "header": "tr|A0AC58GN23-1|A0AC58GN23_DANRE Computationally mapped isoform of Serine protease HTRA2, mitochondrial isoform X2 OS=Danio rerio OX=7955 GN=si:dkey-10b15.8 PE=3 SV=1 CANONICAL=A0A8M9PLU9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:560031", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560031", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NG53-1", "protein_name": "Uncharacterized protein LOC100003308", "gene_name": "htra2-3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSPFSLKNTITSGIVSSAQRGSKELGLSNSNMDYIQTDATIDFGNSGGPLINLDGEVIGINTMKVTAGISFAIPSGRVRLFLDRSADKQKSWFGESGSKRRYIGVMMLTLTPSIIKELRMRDLSFPDVSHGVLIHRVIVGSPANRAGMKPGDVIIEINGVKVNTSEEIYNAVRTSESLNVVVRRGADLLMLHMTPESTE", "length": 200 }, "evidence": [ { "id": "HGNC:14348", "url": "https://alliancegenome.org/gene/HGNC:14348#orthology", "database": "AGR" }, { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" }, { "id": "MGI:1928676", "url": "https://alliancegenome.org/gene/MGI:1928676#orthology", "database": "AGR" }, { "id": "RGD:1308906", "url": "https://alliancegenome.org/gene/RGD:1308906#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PTZ3-1", "protein_name": "Uncharacterized protein LOC100003428", "gene_name": "htra2-10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSPFSLKNTITSGIVSSAQRGSKELGLSNSNMDYIQTDATIDFGNSGGPLINLDGEVIGINTMKVTAGISFAIPSDRVRLFLDRSADKQKSWFGESGSKRRYIGVMMLTLTPSIIEELRMRDPSFADVSHGVLIHRVIVGSPANRAGMNPGDVIIEINGVKVNTSEEIYNAVRTSESLNVVVRRGADLLMLHMTPESTE", "length": 200 }, "evidence": [ { "id": "HGNC:14348", "url": "https://alliancegenome.org/gene/HGNC:14348#orthology", "database": "AGR" }, { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" }, { "id": "MGI:1928676", "url": "https://alliancegenome.org/gene/MGI:1928676#orthology", "database": "AGR" }, { "id": "RGD:1308906", "url": "https://alliancegenome.org/gene/RGD:1308906#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QK16-1", "protein_name": "LOW QUALITY PROTEIN: serine protease HTRA2, mitochondrial", "gene_name": "htra2-7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSPFSLKNTITSGIISSAQRGSKELGLSNSNMDYIHTDATIDFGNSGGPLINLDGEVIGINTMKMTAGISFAIPSDRVRLFLDRSADKQESWFGESGWKRRYIGVMMLTLTPSIIEELRMRDPSFPDVSHGVLIHRVIVGSPANRAGMKPGDVIIEINGVKVNTSEEIYNAVRTXNVVVRRGADLLMLHMTPESTE", "length": 197 }, "evidence": [ { "id": "HGNC:14348", "url": "https://alliancegenome.org/gene/HGNC:14348#orthology", "database": "AGR" }, { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" }, { "id": "MGI:1928676", "url": "https://alliancegenome.org/gene/MGI:1928676#orthology", "database": "AGR" }, { "id": "RGD:1308906", "url": "https://alliancegenome.org/gene/RGD:1308906#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2RT60-1", "protein_name": "Serine protease HTRA4", "gene_name": "Htra4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFQRLWAVRTQFLLLWLLLPAVPVPWAEARRSRVSLPCPDACDPTRCPTLPTCSAGLAPVPDRCGCCRVCAAAEGQECGGARGRPCAPRLRCGAPFSRDPSGGAWLGTCGCAEGAEDAVVCGSDGRTYPSLCALRKENRAARQRGALPAVPVQKGACEEAGTTRAGRLRRKYNFIAAVVEKVAPSVVHLQLFRRSPLTNQEIPSSSGSGFIVSEDGLIVTNAHVLTNQQKIQVELQSGARYEATVKDIDHKLDLALIKIEPDTELPVLLLGRSSDLRAGEFVVALGSPFSLQNTVTAGIVSTTQRGGRELGLKNSDIDYIQTDAIINHGNSGGPLVNLDGDVIGINTLKVTAGISFAIPSDRIRQFLEDYHERQLKGKAPLQKKYLGLRMLPLTLNLLQEMKRQDPEFPDVSSGVFVYEVIQGSAAASSGLRDHDVIVSINGQPVTTTTDVIEAVKDNDFLSIIVLRGSQTLFLTVTPEIIN", "length": 483 }, "evidence": [ { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A9JRB3-1", "protein_name": "Serine protease HTRA1B", "gene_name": "htra1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRLLILCASIILVPLLCDARIIKRYVIGCPERCDKSLCPPIPPDCLAGDILDQCDCCPVCAAGEGESCGGTGKLGDPECGEGLECAVSDGVGATTTVRRRGKTGVCVCKSSEPVCGSDGVSYRNICELKRVSNRAQKLQQPPIIFIQRGACGKGHEENPDSLRHRYNFIADVVEKIAPAVVHIELFRKNVFNREVAVASGSGFVVSEDGLIVTNAHVVANKHRVKVELKTGTTYDAKIKDVDEKADIALIKIDAPMKLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFLAESHDRQAKGKTATKKKYIGVRMMTLTPTLAKELKQRKNDFPDVTSGAYVIEVIPKTPAEVGGLKESDVIISINGQRITSASDVSTAIKTDESLRAVVRRGNEDIILTIIPEEIDP", "length": 476 }, "evidence": [ { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B0BNB9-1", "protein_name": "Serine protease HTRA2, mitochondrial", "gene_name": "Htra2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALKAGRGANWSLRAWRALGGIFWRKGPLLAPDLRALLTSGTPDPQARMTYGTPSLPARVPLGVLASRANLTSGTPDLWVRLTVGTPGSSDQEDCGSPGSRRREWLAVALGAGGAVLLLLWGWGRGPSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPISNGSGFIVASDGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGISGSQRRYIGVMMLTLTPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPADVILAIGEKMIQNAEDVYEAVRTQSQLAVRIRRGPETLTLYVTPEVTE", "length": 458 }, "evidence": [ { "id": "HGNC:14348", "url": "https://alliancegenome.org/gene/HGNC:14348#orthology", "database": "AGR" }, { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-238", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-238#orthology", "database": "AGR" }, { "id": "MGI:1928676", "url": "https://alliancegenome.org/gene/MGI:1928676#orthology", "database": "AGR" }, { "id": "RGD:1308906", "url": "https://alliancegenome.org/gene/RGD:1308906#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZA76-1", "protein_name": "Serine protease HTRA3", "gene_name": "Htra3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQARALLPATLATLATLAVSVLAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHTVCGTDGHTYADVCALQAASRRALQISGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIVTNAHVVSSSNTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATILIHPNKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQDKHVKDWKKRFIGIRMRTITPSLVEELKTANPDFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEAVLNESSLLLEVRRGNDDLLFSIMPEVVM", "length": 459 }, "evidence": [ { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZKF5-1", "protein_name": "Serine protease HTR4", "gene_name": "Htra4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRSKMSSQRLWAVRAQFLLLWLLLWAAPVPWAEARRSRVSLPCPDACDPTRCPPLPSCSAGSALVPDRCGCCQVCAAVEGQECGGARGRPCVPGLRCGAPFSREPSGRAWLGTCGCAEGAEGAAVCGSDGRTYPSLCALRKENRAARQRGALPAVPVQKGACGDSGTTRAGRLRTKYNFIAAVVEKVAPSVVHLQLFRRSPLTNQEIPSSSGSGFIVSEDGLIVTNAHVLTNQQKIQVELQNGAQYEATVKDIDHKLDLALIKIEPDTDLPVLLLGRSSDLRAGEFVVALGSPFSLQNTVTAGIVSTTQRGGKELGLKDSDIDYIQTDAIINHGNSGGPLVNLDGDVIGINTLKVTAGISFAIPSDRIRQFLADYHERQLKGKAPLQKKYLGLRMLPLTLNLLQEMKRQDPDFPDVSSGVFVYEVIQGSAAASSGLRDHDVIVSINGQPVTTTTDVIEAVKDNAFLSIIVLRGSQTLFLTVTPEIIN", "length": 488 }, "evidence": [ { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43464-1", "protein_name": "Serine protease HTRA2, mitochondrial", "gene_name": "HTRA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPRAGRGAGWSLRAWRALGGIRWGRRPRLTPDLRALLTSGTSDPRARVTYGTPSLWARLSVGVTEPRACLTSGTPGPRAQLTAVTPDTRTREASENSGTRSRAWLAVALGAGGAVLLLLWGGGRGPPAVLAAVPSPPPASPRSQYNFIADVVEKTAPAVVYIEILDRHPFLGREVPISNGSGFVVAADGLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRRYIGVMMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAVRTQSQLAVQIRRGRETLTLYVTPEVTE", "length": 458 }, "evidence": [ { "id": "HGNC:14348", "url": "https://alliancegenome.org/gene/HGNC:14348#orthology", "database": "AGR" }, { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-238", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-238#orthology", "database": "AGR" }, { "id": "MGI:1928676", "url": "https://alliancegenome.org/gene/MGI:1928676#orthology", "database": "AGR" }, { "id": "RGD:1308906", "url": "https://alliancegenome.org/gene/RGD:1308906#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P53920-1", "protein_name": "Pro-apoptotic serine protease NMA111", "gene_name": "NMA111", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTISLSNIKKRDHSKISDGTSGESSLVKRKQLESATGDQEEEYTDHEIIIEPLHFANNNNTVLTDSENYLRWQNTISNVVKSVVSIHFSQVAPFDCDSALVSEATGFVVDAKLGIILTNRHVVGPGPFVGYVVFDNHEECDVIPIYRDPVHDFGFLKFDPKNIKYSKIKALTLKPSLAKVGSEIRVVGNDAGEKLSILAGFISRIDRNAPEYGELTYNDFNTEYIQAAASASGGSSGSPVVNIDGYAVALQAGGSTEASTDFFLPLDRILRALICIQTNKPITRGTIQVQWLLKPYDECRRLGLTSERESEARAKFPENIGLLVAETVLREGPGYDKIKEGDTLISINGETISSFMQVDKIQDENVGKEIQLVIQRGGVECTVTCTVGDLHAITPHRYVEVCGATFHELSYQMARFYALPVRGVFLSSASGSFNFDSKERVGWIVDSIDNKETPDLDTFIEIMKTIPDRKRVTVRYHHLTDQHSPLVTSIYIDRHWCNEFRVYTRNDTTGIWDYKNVADPLPADALKPRSAKIIPIPVNNEKVAKLSSSLCTVATMAAVPLDSLSADILKTSGLIIDAEKGYVLVSRRVVPHDCLDTFVTIADSLVVPATVEFLHPTHNFAIVKYDPELVKAPLITPKLSTTRMKRGDKLQFIGFTQNDRIVTSETTVTDISSVSIPSNLIPRYRATNLEAISIDCNVSTRCNSGILTDNDGTVRGLWLPFLGERLENKEKVYLMGLDIMDCREVIDILKNGGKPRVSIVDAGFGSISVLQARIRGVPEEWIMRMEHESNNRLQFITVSRVSYTEDKIHLETGDVILSVNGKLVTEMNDLNGVVSSADGILPSAMLDFKVVRDGNIVDLKIKTVEVQETDRFVIFAGSILQKPHHAVLQAMVDVPKGVYCTFRGESSPALQYGISATNFITHVNEIETPDLDTFLKVVKTIPDNSYCKMRLMTFDNVPFAISLKTNYHYFPTAELKRDNITHKWIEKEFTGNSQSEK", "length": 997 }, "evidence": [ { "id": "HGNC:14348", "url": "https://alliancegenome.org/gene/HGNC:14348#orthology", "database": "AGR" }, { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P83105-1", "protein_name": "Serine protease HTRA4", "gene_name": "HTRA4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIRPQLRTAGLGRCLLPGLLLLLVPVLWAGAEKLHTQPSCPAVCQPTRCPALPTCALGTTPVFDLCRCCRVCPAAEREVCGGAQGQPCAPGLQCLQPLRPGFPSTCGCPTLGGAVCGSDRRTYPSMCALRAENRAARRLGKVPAVPVQWGNCGDTGTRSAGPLRRNYNFIAAVVEKVAPSVVHVQLWGRLLHGSRLVPVYSGSGFIVSEDGLIITNAHVVRNQQWIEVVLQNGARYEAVVKDIDLKLDLAVIKIESNAELPVLMLGRSSDLRAGEFVVALGSPFSLQNTATAGIVSTKQRGGKELGMKDSDMDYVQIDATINYGNSGGPLVNLDGDVIGVNSLRVTDGISFAIPSDRVRQFLAEYHEHQMKGKAFSNKKYLGLQMLSLTVPLSEELKMHYPDFPDVSSGVYVCKVVEGTAAQSSGLRDHDVIVNINGKPITTTTDVVKALDSDSLSMAVLRGKDNLLLTVIPETIN", "length": 476 }, "evidence": [ { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P83110-1", "protein_name": "Serine protease HTRA3", "gene_name": "HTRA3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQARALLLAALAALALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGGPLDSPCGESLECVRGLCRCRWSHAVCGTDGHTYANVCALQAASRRALQLSGTPVRQLQKGACPLGLHQLSSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDRITRFLTEFQDKQIKDWKKRFIGIRMRTITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQEAVLTESPLLLEVRRGNDDLLFSIAPEVVM", "length": 453 }, "evidence": [ { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6GMI0-1", "protein_name": "Serine protease HTRA1A", "gene_name": "htra1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MILVTLFCICALVTSLQADARLSKRYVIGGCPSHCDKSMCPTMPKDCSTGQVMDHCNCCLVCASGEGEACGGVGKLGDPVCGESLECSVTGGVSYSATVRRRGKQGVCVCKSSDPVCGSDGVSYRDICELKRVSNRAQSLQQPPVLFIQRGACGTSLHDNPNSLRYKYNFIADVVEKIAPAVVHIELYRKMVYSKREMAVASGSGFVVSDDGLIVTNAHVVANKNRVKVELKNGASYDAKIKDVDEKADIALIKIDLPNKLPVLLLGRSADLRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIRQFLAESYDRLARGRGTTKKRYIGVRMMTLTPSLSKELKGRLRDFPDITSGAYVIEVISKTPAAAGGLKEHDVIISINGQRISTATDVSAIIKKESSLRVVVRRGNEDIILTIIPMEIDP", "length": 479 }, "evidence": [ { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q92743-1", "protein_name": "Serine protease HTRA1", "gene_name": "HTRA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQIPRAALLPLLLLLLAAPASAQLSRAGRSAPLAAGCPDRCEPARCPPQPEHCEGGRARDACGCCEVCGAPEGAACGLQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVCGSDANTYANLCQLRAASRRSERLHRPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIAPAVVHIELFRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRMMSLTSSKAKELKDRHRDFPDVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVIKRESTLNMVVRRGNEDIMITVIPEEIDP", "length": 480 }, "evidence": [ { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D236-3", "protein_name": "Serine protease HTRA3", "gene_name": "Htra3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQARALLPATLAILATLAVLALAREPPAAPCPARCDVSRCPSPRCPGGYVPDLCNCCLVCAASEGEPCGRPLDSPCGDSLECVRGVCRCRWTHTVCGTDGHTYADVCALQAASRRALQVSGTPVRQLQKGACPSGLHQLTSPRYKFNFIADVVEKIAPAVVHIELFLRHPLFGRNVPLSSGSGFIMSEAGLIVTNAHVVSSSSTASGRQQLKVQLQNGDAYEATIQDIDKKSDIATIVIHPKKKLPVLLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQRDGKELGLRDSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVAAGISFAIPSDRITRFLSEFQNKHVKDWKKRFIGIRMRTITPSLVEELKAANPDFPAVSSGIYVQEVVPNSPSQRGGIQDGDIIVKVNGRPLADSSELQEAVLNESSLLLEVRRGNDDLLFSIIPEVVM", "length": 459 }, "evidence": [ { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JIY5-1", "protein_name": "Serine protease HTRA2, mitochondrial", "gene_name": "Htra2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALKAGRGANWSLRAWRALGGIFWRKPPLLAPDLRALLTSGTPDSQIWMTYGTPSLPAQVPEGFLASRADLTSRTPDLWARLNVGTSGSSDQEARRSPGSRRREWLAVAVGAGGAVVLLLWGWGRGLSTVLAAVPAPPPTSPRSQYNFIADVVEKTAPAVVYIEILDRHPFSGREVPISNGSGFVVASDGLIVTNAHVVADRRRVRVRLPSGDTYEAMVTAVDPVADIATLRIQTKEPLPTLPLGRSADVRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQNNVEYIQTDAAIDFGNSGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLREFLHRGEKKNSWFGTSGSQRRYIGVMMLTLTPSILIELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEKLAQNAEDVYEAVRTQSQLAVRIRRGSETLTLYVTPEVTE", "length": 458 }, "evidence": [ { "id": "HGNC:14348", "url": "https://alliancegenome.org/gene/HGNC:14348#orthology", "database": "AGR" }, { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-238", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-238#orthology", "database": "AGR" }, { "id": "MGI:1928676", "url": "https://alliancegenome.org/gene/MGI:1928676#orthology", "database": "AGR" }, { "id": "RGD:1308906", "url": "https://alliancegenome.org/gene/RGD:1308906#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QZK5-1", "protein_name": "Serine protease HTRA1", "gene_name": "Htra1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQFLRTALLSLLLLLLAAPSLALPSGISRSAPAATVCPEHCDPTRCAPPPTDCEGGRVRDACGCCEVCGALEGAVCGLQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVCGSDAKTYTNLCQLRAASRRSEKLRQPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIAPAVVHIELYRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKNRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKTVTKKKYIGIRMMSLTSSKAKELKDRHRDFPDVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVTANDVSDVIKKENTLNMVVRRGNEDIVITVVPEEIDP", "length": 480 }, "evidence": [ { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9R118-1", "protein_name": "Serine protease HTRA1", "gene_name": "Htra1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQSLRTTLLSLLLLLLAAPSLALPSGTGRSAPAATVCPEHCDPTRCAPPPTDCEGGRVRDACGCCEVCGALEGAACGLQEGPCGEGLQCVVPFGVPASATVRRRAQAGLCVCASSEPVCGSDAKTYTNLCQLRAASRRSEKLRQPPVIVLQRGACGQGQEDPNSLRHKYNFIADVVEKIAPAVVHIELYRKLPFSKREVPVASGSGFIVSEDGLIVTNAHVVTNKNRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSELRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNSGGPLVNLDGEVIGINTLKVTAGISFAIPSDKIKKFLTESHDRQAKGKAVTKKKYIGIRMMSLTSSKAKELKDRHRDFPDVLSGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVTANDVSDVIKKENTLNMVVRRGNEDIVITVIPEEIDP", "length": 480 }, "evidence": [ { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VFJ3-1", "protein_name": "Serine protease HTRA2, mitochondrial", "gene_name": "HtrA2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALRGSHRLEVIFKRCIASPVLHSHAANRRSSQLAIKEGDPNSNGNSGQYQQNGEQKEKGWRRLVRFFVPFSLGAVVSAAIIQREDLTPTIAASKMTGRRRDFNFIADVVAGCADSVVYIEIKDTRHFDYFSGQPITASNGSGFIIEQNGLILTNAHVVINKPHTMVQVRLSDGRTFPATIEDVDQTSDLATLRIQVNNLSVMRLGKSSTLRSGEWVVALGSPLALSNTVTAGVISSTQRASQELGLRNRDINYLQTDAAITFGNSGGPLVNLDGEAIGVNSMKVTAGISFAIPIDYVKVFLERAAEKRKKGSAYKTGYPVKRYMGITMLTLTPDILFELKSRSQNMPSNLTHGVLVWKVIVGSPAHSGGLQPGDIVTHINKKEIKNSSDVYDALADNSKTLDIVILRGVKQMHVTITPEDP", "length": 422 }, "evidence": [ { "id": "HGNC:14348", "url": "https://alliancegenome.org/gene/HGNC:14348#orthology", "database": "AGR" }, { "id": "FB:FBgn0038233", "url": "https://alliancegenome.org/gene/FB:FBgn0038233#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-238", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-238#orthology", "database": "AGR" }, { "id": "MGI:1928676", "url": "https://alliancegenome.org/gene/MGI:1928676#orthology", "database": "AGR" }, { "id": "RGD:1308906", "url": "https://alliancegenome.org/gene/RGD:1308906#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU9" } ], "pmid": "" }, { "name": "peptidase activity", "id": "GO:0008233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008233", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLU9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLU9", "url": 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], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PLU9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLU9" }, { "id": "PS50106", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PDZ", "eco_id": "ECO_0000259", "start_pos": 132, "end_pos": 176, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 } 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PLV0-1", "uniprot_ac": "A0A8M9PLV0", "uniprot_id": "A0A8M9PLV0_DANRE", "mass": { "chemical_mass": 28154.0, "monoisotopic_mass": 28154.0 }, "refseq": { "ac": "XP_021322165", "name": "RING finger protein 228", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322165" }, "gene_names": [ { "name": "rnf228", "type": "recommended", "evidence": [ { "id": "A0A8M9PLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLV0" } ] }, { "name": "rnf228", "type": "synonym", "evidence": [ { "id": "XP_021322165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322165" } ] } ], "protein_names": [ { "name": "RING finger protein 228", "type": "synonym", "evidence": [ { "id": "XP_021322165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322165" }, { "id": "A0A8M9PLV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLV0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322165" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLV0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLV0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rnf228", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLV0", "locus": {} } ], "crossref": [ { "id": "A0A8M9PLV0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PLV0", "database": "AlphaFoldDB", "categories": [] }, { "id": "110437922", "url": "https://www.ncbi.nlm.nih.gov/gene/110437922", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": 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[ "Protein Classification" ] }, { "id": "PTHR22791:SF17", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22791:SF17", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14634", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14634", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322165", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322165", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLV0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLV0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PLW8-1", "uniprot_ac": "A0A8M9PLW8", "uniprot_id": "A0A8M9PLW8_DANRE", "mass": { "chemical_mass": 9848.0, "monoisotopic_mass": 9848.0 }, "refseq": { "ac": "XP_021322185", "name": "uncharacterized protein si:ch1073-340i21.1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322185" }, "gene_names": [ { "name": "si:ch1073-340i21.1", "type": "recommended", "evidence": [ { "id": "A0A8M9PLW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLW8" } ] }, { "name": "si:ch1073-340i21.1", "type": "synonym", "evidence": [ { "id": "XP_021322185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322185" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch1073-340i21.1", "type": "synonym", "evidence": [ { "id": "A0A8M9PLW8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLW8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch1073-340i21.1", "type": "synonym", "evidence": [ { "id": "XP_021322185", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322185" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322185.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322185" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PLW8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLW8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch1073-340i21.1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLW8", "locus": {} } ], "crossref": [ { "id": "A0A8M9PLW8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PLW8", "database": "AlphaFoldDB", "categories": [] }, { "id": "100536813", "url": "https://www.ncbi.nlm.nih.gov/gene/100536813", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100536813", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536813", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_021322185", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322185", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLW8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLW8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLW8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDFDLAAAVGDEEVKKKEGKQVEGIFGKKDKDKSKDKHKDKDKKHKEHKDKHKDKEHKDKDKKKKDKEHKKKDGGKSSSSSSSDSD", "length": 86, "header": "tr|A0A8M9PLW8-1|A0A8M9PLW8_DANRE Isoform 1 of Uncharacterized protein si:ch1073-340i21.1 OS=Danio rerio OX=7955 GN=si:ch1073-340i21.1 PE=1 SV=2 CANONICAL=A0A8M9PLW8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLW8/entry#A0A8M9PLW8-1", "sequence": { "sequence": "MDFDLAAAVGDEEVKKKEGKQVEGIFGKKDKDKSKDKHKDKDKKHKEHKDKHKDKEHKDKDKKKKDKEHKKKDGGKSSSSSSSDSD", "length": 86, "header": "tr|A0A8M9PLW8-1|A0A8M9PLW8_DANRE Isoform 1 of Uncharacterized protein si:ch1073-340i21.1 OS=Danio rerio OX=7955 GN=si:ch1073-340i21.1 PE=1 SV=2 CANONICAL=A0A8M9PLW8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100536813", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536813", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PM92-1", "uniprot_ac": "A0A8M9PM92", "uniprot_id": "A0A8M9PM92_DANRE", "mass": { "chemical_mass": 97630.0, "monoisotopic_mass": 97630.0 }, "refseq": { "ac": "XP_009291537", "name": "von Willebrand factor A domain-containing protein 7", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291537" }, "gene_names": [ { "name": "vwa11", "type": "recommended", "evidence": [ { "id": "A0A8M9PM92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM92" } ] }, { "name": "vwa11", "type": "synonym", "evidence": [ { "id": "XP_009291537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291537" } ] } ], "protein_names": [ { "name": "von Willebrand factor A domain-containing protein 7", "type": "synonym", "evidence": [ { "id": "XP_009291537", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291537" }, { "id": "A0A8M9PM92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM92/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009291537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291537" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PM92", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM92" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "vwa11", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM92", "locus": {} } ], "crossref": [ { "id": "cd00198", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00198", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "565211", "url": "https://www.ncbi.nlm.nih.gov/gene/565211", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052577", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052577", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056475", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056475", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056862", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056862", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057615", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057615", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565211", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565211", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PM92", "url": "https://www.orthodb.org/?gene=A0A8M9PM92", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14905", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14905", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14905:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14905:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25107", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25107", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009291537", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291537", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PM92", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PM92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKSALAVVALLALVSRLQAFVSVGGSGNTHVTITGNTVMAKITEVCEAVAEAEGREFKPTGSSVEELLRACLGTTGEVSGAKFRTALNQIYMQNGIVDRDFMNSPSHHFNNEAFAEGRNLIIQGTAAIKANVRSDNLQSARETLGRVCHTLQDFYSHSNWVELGNKSPYANLIRPDLNVENIADVEMPTCSDCASGTCTNQLLPAVLNGKFLTSGYMGLFSSDKPQGKCSHGGASDLSSSQNPRGGISKDERQSHNSNQHNSAVNLASEATLELLEDIRGAIGNKDFLRLMGIARSAVLAFVIDTTGSMADDIAEAKRVAYNIIDTKKGTQDEPSEYILVPFNDPKFGPLIRTTNPDVMKSEISKLKAEGGGDIPEMCLSALQLSLTGAPSSSHIYVFTDAPPKDTHLEKTITALIRSTKSTVSFFMTPSKRRRRAVAAASTFQVYYDMALASGGQAIEVPKSSLSQATDIIVDTSTSALVTILQRSRSPGRKESFPFLLDKSMSNTTIYITGSSLTFNLHSPSGVSQSNSVVNGPLGTIHRVGNLQRIQLNGSDTGLWQIEMTTTQPYTVKVTGQSAITFIYDFVEEFKGPHPGFAVIDGRPSAGSPAKLLLTLTGEKGPEALEVHQVALVEVSGEKVSNGTVDKMADGDLLVTVKEVPGGEFVVLLKGKDKTYSSLFQRQTTTQMSLSKVTIKAVADSSMLPGEVFKLNFTVTTNGTGGAYTIRARNDKNIPMSHPSTLNVASGGSAQGTISLTPPSATLSGTDVTLTIEAEGPGGADSNYAVLRLSVLSKVTDLTPPKCSIVDVQGVCYASACSSSNWELSVNITDGNGTGIQSISIQQGSGNFTQKVAEDVVMGRYEASCCSTSVTLSAVDKVGNVGRCSYNMKSGTGPRLFTMSIPLWASLLLYVVLRDVSL", "length": 918, "header": "tr|A0A8M9PM92-1|A0A8M9PM92_DANRE Isoform 1 of von Willebrand factor A domain-containing protein 7 OS=Danio rerio OX=7955 GN=vwa11 PE=4 SV=1 CANONICAL=A0A8M9PM92-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PM92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM92/entry#A0A8M9PM92-1", "sequence": { "sequence": "MVKSALAVVALLALVSRLQAFVSVGGSGNTHVTITGNTVMAKITEVCEAVAEAEGREFKPTGSSVEELLRACLGTTGEVSGAKFRTALNQIYMQNGIVDRDFMNSPSHHFNNEAFAEGRNLIIQGTAAIKANVRSDNLQSARETLGRVCHTLQDFYSHSNWVELGNKSPYANLIRPDLNVENIADVEMPTCSDCASGTCTNQLLPAVLNGKFLTSGYMGLFSSDKPQGKCSHGGASDLSSSQNPRGGISKDERQSHNSNQHNSAVNLASEATLELLEDIRGAIGNKDFLRLMGIARSAVLAFVIDTTGSMADDIAEAKRVAYNIIDTKKGTQDEPSEYILVPFNDPKFGPLIRTTNPDVMKSEISKLKAEGGGDIPEMCLSALQLSLTGAPSSSHIYVFTDAPPKDTHLEKTITALIRSTKSTVSFFMTPSKRRRRAVAAASTFQVYYDMALASGGQAIEVPKSSLSQATDIIVDTSTSALVTILQRSRSPGRKESFPFLLDKSMSNTTIYITGSSLTFNLHSPSGVSQSNSVVNGPLGTIHRVGNLQRIQLNGSDTGLWQIEMTTTQPYTVKVTGQSAITFIYDFVEEFKGPHPGFAVIDGRPSAGSPAKLLLTLTGEKGPEALEVHQVALVEVSGEKVSNGTVDKMADGDLLVTVKEVPGGEFVVLLKGKDKTYSSLFQRQTTTQMSLSKVTIKAVADSSMLPGEVFKLNFTVTTNGTGGAYTIRARNDKNIPMSHPSTLNVASGGSAQGTISLTPPSATLSGTDVTLTIEAEGPGGADSNYAVLRLSVLSKVTDLTPPKCSIVDVQGVCYASACSSSNWELSVNITDGNGTGIQSISIQQGSGNFTQKVAEDVVMGRYEASCCSTSVTLSAVDKVGNVGRCSYNMKSGTGPRLFTMSIPLWASLLLYVVLRDVSL", "length": 918, "header": "tr|A0A8M9PM92-1|A0A8M9PM92_DANRE Isoform 1 of von Willebrand factor A domain-containing protein 7 OS=Danio rerio OX=7955 GN=vwa11 PE=4 SV=1 CANONICAL=A0A8M9PM92-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:565211", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565211", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PM92", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM92" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" }, { "start_pos": 553, "end_pos": 555, "annotation": "n_glycosylation_sequon" }, { "start_pos": 642, "end_pos": 644, "annotation": "n_glycosylation_sequon" }, { "start_pos": 712, "end_pos": 714, "annotation": "n_glycosylation_sequon" }, { "start_pos": 718, "end_pos": 720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" }, { "start_pos": 832, "end_pos": 834, "annotation": "n_glycosylation_sequon" }, { "start_pos": 847, "end_pos": 849, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PM92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM92" }, { "id": "PF25106", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25106" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Hemicentin-1-like von Willebrand factor A", "eco_id": "ECO_0000259", "start_pos": 300, "end_pos": 462, "start_aa": "Leu", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PM92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM92" }, { "id": "PF23560", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23560" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Hemicentin/VWA7 galactose-binding", "eco_id": "ECO_0000259", "start_pos": 482, "end_pos": 578, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PM92", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PM92" }, { "id": "PF23619", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23619" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWA7 Ig-like", "eco_id": "ECO_0000259", "start_pos": 693, "end_pos": 792, "start_aa": "Val", "end_aa": "Leu", 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"MAGTTGNEESHKLACGSQRPGLQLQQDTDQRGIVIQLTDTEGEWDNLDDNDLIFTLDCDGKKSLSSIRSQRPCSVDIQTEWGTSSSAFNVPLSPSSPGSLGNSFPIGSAFLSPTHRPLSSLVKSLSTEIELKESSLKPKPLISLVKSISTELSRSEPEVSQSRSDSKLNLHLWAQFTQPKSRNGDSRTAPPTPVNLSPTETKASFFKMELEDTRRKLSEAMQEPLSMFSKIMREDSVGSPKHQRSTGSVDSPSYKGLGIGKSNTDLTASESPKSVRKADNEFLPECNWPVRHRKRCMQKSSLSYDYHSRQVDAGNVFESRTHAGFSTNMDRSDQDGLAEDGMEQCSSAVPGVGLFFVAVLSYCYLILPLSAYWSGLFLGLVFGLMLGLVLIHWGSIRPLSTSKQHRLHGTTCDNILSESLQSNPFPLKGWMNEMYTYDPETYQPSLMHSVHATLDGPCLRLDYPRNNIPRWATLDEPCYEKHFIHSRIFRLTGSKVFLLPLALAHKRVWNRKYPICISLADGERALEEGEMVEVQKAEKPATNVSHPVTLYLFGRTGREKEEWFHRLFSVSIQNEEDHYESTFGDKFVSHEENLISQSHGGEGSVKDSSEDVFHSDPLGRVKENTVPDYSSYMTSLMFSAHASPPQSPSQSSTQGSPTEKEQQTFCCHEDETRPVWLNALIGRIFWDFLREKYWADKVQQKIQRKLSKIRLPYFMDELTLTELAMGSSLPQITGTSLPQVNSRGLWLHLEMEYTGALQMTLETKINLSKLGKDGILEAETELEAFSVFSRSRLSVLADSDEESSSAGSSDEEDVSSADTQGALTDKTLTGVDGAAAGGSTSRRILKFVDKIAKSKYFQKATENEYIKKKIEEMSNTPLLLAVEVQELSGTLVVNIPPPPTDRIWYSFCGPPKLDLRVRPKLGEREVTFCHVTEWIEKKLQDEFQNVFVLPNMDDIYLPLMHSGMDNPPLAQHPAKLSQNSSMASTDRSDLEHCAELQ", "length": 997, "header": "tr|A0A8M9PMA7-1|A0A8M9PMA7_DANRE Isoform 1 of Testis-expressed protein 2 isoform X1 OS=Danio rerio OX=7955 GN=tex2l PE=4 SV=1 CANONICAL=A0A8M9PMA7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PMA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMA7/entry#A0A8M9PMA7-1", "sequence": { "sequence": "MAGTTGNEESHKLACGSQRPGLQLQQDTDQRGIVIQLTDTEGEWDNLDDNDLIFTLDCDGKKSLSSIRSQRPCSVDIQTEWGTSSSAFNVPLSPSSPGSLGNSFPIGSAFLSPTHRPLSSLVKSLSTEIELKESSLKPKPLISLVKSISTELSRSEPEVSQSRSDSKLNLHLWAQFTQPKSRNGDSRTAPPTPVNLSPTETKASFFKMELEDTRRKLSEAMQEPLSMFSKIMREDSVGSPKHQRSTGSVDSPSYKGLGIGKSNTDLTASESPKSVRKADNEFLPECNWPVRHRKRCMQKSSLSYDYHSRQVDAGNVFESRTHAGFSTNMDRSDQDGLAEDGMEQCSSAVPGVGLFFVAVLSYCYLILPLSAYWSGLFLGLVFGLMLGLVLIHWGSIRPLSTSKQHRLHGTTCDNILSESLQSNPFPLKGWMNEMYTYDPETYQPSLMHSVHATLDGPCLRLDYPRNNIPRWATLDEPCYEKHFIHSRIFRLTGSKVFLLPLALAHKRVWNRKYPICISLADGERALEEGEMVEVQKAEKPATNVSHPVTLYLFGRTGREKEEWFHRLFSVSIQNEEDHYESTFGDKFVSHEENLISQSHGGEGSVKDSSEDVFHSDPLGRVKENTVPDYSSYMTSLMFSAHASPPQSPSQSSTQGSPTEKEQQTFCCHEDETRPVWLNALIGRIFWDFLREKYWADKVQQKIQRKLSKIRLPYFMDELTLTELAMGSSLPQITGTSLPQVNSRGLWLHLEMEYTGALQMTLETKINLSKLGKDGILEAETELEAFSVFSRSRLSVLADSDEESSSAGSSDEEDVSSADTQGALTDKTLTGVDGAAAGGSTSRRILKFVDKIAKSKYFQKATENEYIKKKIEEMSNTPLLLAVEVQELSGTLVVNIPPPPTDRIWYSFCGPPKLDLRVRPKLGEREVTFCHVTEWIEKKLQDEFQNVFVLPNMDDIYLPLMHSGMDNPPLAQHPAKLSQNSSMASTDRSDLEHCAELQ", "length": 997, "header": "tr|A0A8M9PMA7-1|A0A8M9PMA7_DANRE Isoform 1 of Testis-expressed protein 2 isoform X1 OS=Danio rerio OX=7955 GN=tex2l PE=4 SV=1 CANONICAL=A0A8M9PMA7-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PTF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMA7/entry#A0A8M9PTF2-1", "sequence": { "sequence": "MAGTTGNEESHKLACGSQRPGLQLQQDTDQRGIVIQLTDTEGEWDNLDDNDLIFTLDCDGKKSLSSIRSQRPCSVDIQTEWGTSSSAFNVPLSPSSPGSLGNSFPIGSAFLSPTHRPLSSLVKSLSTEIELKESSLKPKPLISLVKSISTELSRSEPEVSQSRSDSKLNLHLWAQFTQPKSRNGDSRTAPPTPVNLSPTETKASFFKMELEDTRRKLSEAMQEPLSMFSKIMREDSVGSPKHQRSTGSVDSPSYKGLGIGKSNTDLTASESPKSVRKADNEFLPECNWPVRHRKRCMQKSSLSYDYHSRQVDAGNVFESRTHAGFSTNMDRSDQDGLAEDGMEQCSSAVPGVGLFFVAVLSYCYLILPLSAYWSGLFLGLVFGLMLGLVLIHWGSIRPLSTSKQHRLHGTTCDNILSESLQSNPFPLKGWMNEMYTYDPETYQPSLMHSVHATLDGPCLRLDYPRNNIPRWATLDEPCYEKHFIHSRIFRLTGSKVFLLPLALAHKRVWNRKYPICISLADGERALEEGEMVEVQKAEKPATNVSHPVTLYLFGRTGREKEEWFHRLFSVSIQNEEDHYESTFGDKFVSHEENLISQSHGGEGSVKDSSEDVFHSDPLGRVKENTVPDYSSYMTSLMFSAHASPPQSPSQSSTQGSPTEKEQTFCCHEDETRPVWLNALIGRIFWDFLREKYWADKVQQKIQRKLSKIRLPYFMDELTLTELAMGSSLPQITGTSLPQVNSRGLWLHLEMEYTGALQMTLETKINLSKLGKDGILEAETELEAFSVFSRSRLSVLADSDEESSSAGSSDEEDVSSADTQGALTDKTLTGVDGAAAGGSTSRRILKFVDKIAKSKYFQKATENEYIKKKIEEMSNTPLLLAVEVQELSGTLVVNIPPPPTDRIWYSFCGPPKLDLRVRPKLGEREVTFCHVTEWIEKKLQDEFQNVFVLPNMDDIYLPLMHSGMDNPPLAQHPAKLSQNSSMASTDRSDLEHCAELQ", "length": 996, "header": "tr|A0A8M9PTF2-1|A0A8M9PMA7_DANRE Computationally mapped isoform of Testis-expressed protein 2 isoform X1 OS=Danio rerio OX=7955 GN=tex2l PE=4 SV=1 CANONICAL=A0A8M9PMA7-1" }, "locus": {} }, { "isoform_ac": "A0AB32TJM8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMA7/entry#A0AB32TJM8-1", "sequence": { "sequence": "MAGTTGNEESHKLACGSQRPGLQLQQDTDQRGIVIQLTDTEGSLGNSFPIGSAFLSPTHRPLSSLVKSLSTEIELKESSLKPKPLISLVKSISTELSRSEPEVSQSRSDSKLNLHLWAQFTQPKSRNGDSRTAPPTPVNLSPTETKASFFKMELEDTRRKLSEAMQEPLSMFSKIMREDSVGSPKHQRSTGSVDSPSYKGLGIGKSNTDLTASESPKSVRKADNEFLPECNWPVRHRKRCMQKSSLSYDYHSRQVDAGNVFESRTHAGFSTNMDRSDQDGLAEDGMEQCSSAVPGVGLFFVAVLSYCYLILPLSAYWSGLFLGLVFGLMLGLVLIHWGSIRPLSTSKQHRLHGTTCDNILSESLQSNPFPLKGWMNEMYTYDPETYQPSLMHSVHATLDGPCLRLDYPRNNIPRWATLDEPCYEKHFIHSRIFRLTGSKVFLLPLALAHKRVWNRKYPICISLADGERALEEGEMVEVQKAEKPATNVSHPVTLYLFGRTGREKEEWFHRLFSVSIQNEEDHYESTFGDKFVSHEENLISQSHGGEGSVKDSSEDVFHSDPLGRVKENTVPDYSSYMTSLMFSAHASPPQSPSQSSTQGSPTEKEQQTFCCHEDETRPVWLNALIGRIFWDFLREKYWADKVQQKIQRKLSKIRLPYFMDELTLTELAMGSSLPQITGTSLPQVNSRGLWLHLEMEYTGALQMTLETKINLSKLGKDGILEAETELEAFSVFSRSRLSVLADSDEESSSAGSSDEEDVSSADTQGALTDKTLTGVDGAAAGGSTSRRILKFVDKIAKSKYFQKATENEYIKKKIEEMSNTPLLLAVEVQELSGTLVVNIPPPPTDRIWYSFCGPPKLDLRVRPKLGEREVTFCHVTEWIEKKLQDEFQNVFVLPNMDDIYLPLMHSGMDNPPLAQHPAKLSQNSSMASTDRSDLEHCAELQ", "length": 941, "header": "tr|A0AB32TJM8-1|A0A8M9PMA7_DANRE Computationally mapped isoform of Testis-expressed protein 2 isoform X1 OS=Danio rerio OX=7955 GN=tex2l PE=4 SV=1 CANONICAL=A0A8M9PMA7-1" }, "locus": {} }, { "isoform_ac": "A0AC58GXM3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMA7/entry#A0AC58GXM3-1", "sequence": { "sequence": "MAGTTGNEESHKLACGSQRPGLQLQQDTDQRGIVIQLTDTEGSLGNSFPIGSAFLSPTHRPLSSLVKSLSTEIELKESSLKPKPLISLVKSISTELSRSEPEVSQSRSDSKLNLHLWAQFTQPKSRNGDSRTAPPTPVNLSPTETKASFFKMELEDTRRKLSEAMQEPLSMFSKIMREDSVGSPKHQRSTGSVDSPSYKGLGIGKSNTDLTASESPKSVRKADNEFLPECNWPVRHRKRCMQKSSLSYDYHSRQVDAGNVFESRTHAGFSTNMDRSDQDGLAEDGMEQCSSAVPGVGLFFVAVLSYCYLILPLSAYWSGLFLGLVFGLMLGLVLIHWGSIRPLSTSKQHRLHGTTCDNILSESLQSNPFPLKGWMNEMYTYDPETYQPSLMHSVHATLDGPCLRLDYPRNNIPRWATLDEPCYEKHFIHSRIFRLTGSKVFLLPLALAHKRVWNRKYPICISLADGERALEEGEMVEVQKAEKPATNVSHPVTLYLFGRTGREKEEWFHRLFSVSIQNEEDHYESTFGDKFVSHEENLISQSHGGEGSVKDSSEDVFHSDPLGRVKENTVPDYSSYMTSLMFSAHASPPQSPSQSSTQGSPTEKEQTFCCHEDETRPVWLNALIGRIFWDFLREKYWADKVQQKIQRKLSKIRLPYFMDELTLTELAMGSSLPQITGTSLPQVNSRGLWLHLEMEYTGALQMTLETKINLSKLGKDGILEAETELEAFSVFSRSRLSVLADSDEESSSAGSSDEEDVSSADTQGALTDKTLTGVDGAAAGGSTSRRILKFVDKIAKSKYFQKATENEYIKKKIEEMSNTPLLLAVEVQELSGTLVVNIPPPPTDRIWYSFCGPPKLDLRVRPKLGEREVTFCHVTEWIEKKLQDEFQNVFVLPNMDDIYLPLMHSGMDNPPLAQHPAKLSQNSSMASTDRSDLEHCAELQ", "length": 940, "header": "tr|A0AC58GXM3-1|A0AC58GXM3_DANRE Computationally mapped isoform of Testis-expressed protein 2 isoform X4 OS=Danio rerio OX=7955 GN=tex2l PE=4 SV=1 CANONICAL=A0A8M9PMA7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 192, "start_aa": "Thr", "end_pos": 192, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr192", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100004729", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004729", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMA7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMA7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMA7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMA7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 543, "end_pos": 545, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 979, "end_pos": 981, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PMA7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMA7" }, { "id": "PS51847", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51847" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SMP-LTD", "eco_id": "ECO_0000259", "start_pos": 669, "end_pos": 958, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 192 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 195, "end_pos": 197 }, { "start_pos": 543, "end_pos": 545 }, { "start_pos": 766, "end_pos": 768 }, { "start_pos": 979, "end_pos": 981 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PMB3-1", "uniprot_ac": "A0A8M9PMB3", "uniprot_id": "A0A8M9PMB3_DANRE", "mass": { "chemical_mass": 22352.0, "monoisotopic_mass": 22352.0 }, "refseq": { "ac": "XP_021323396", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323396" }, "gene_names": [ { "name": "LOC110438076", "type": "recommended", "evidence": [ { "id": "A0A8M9PMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMB3" } ] }, { "name": "LOC110438076", "type": "synonym", "evidence": [ { "id": "XP_021323396", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323396" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PMB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMB3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021323396", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323396" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323396", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323396" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMB3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMB3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438076", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMB3", "locus": {} } ], "crossref": [ { "id": "A0A8M9PMB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PMB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438076", "url": "https://www.ncbi.nlm.nih.gov/gene/110438076", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029569", "url": 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"glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 246, "end_pos": 248 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 539, "end_pos": 541 }, { "start_pos": 616, "end_pos": 618 }, { "start_pos": 956, "end_pos": 958 }, { "start_pos": 967, "end_pos": 969 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PMG3-1", "uniprot_ac": "A0A8M9PMG3", "uniprot_id": "A0A8M9PMG3_DANRE", "mass": { "chemical_mass": 49824.0, "monoisotopic_mass": 49824.0 }, "refseq": { "ac": "XP_021328243", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328243" }, "gene_names": [ { "name": "LOC101885345", "type": "recommended", "evidence": [ { "id": "A0A8M9PMG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3" } ] }, { "name": "LOC101885345", "type": "synonym", "evidence": [ { "id": "XP_021328243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328243" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PMG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021328243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328243" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021328243.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328243" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101885345", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3", "locus": {} } ], "crossref": [ { "id": "A0A8M9PMG3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PMG3", "database": "AlphaFoldDB", "categories": [] }, { "id": "101885345", "url": "https://www.ncbi.nlm.nih.gov/gene/101885345", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040255", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040255", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044925", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044925", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885345", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885345", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PMG3", "url": "https://www.orthodb.org/?gene=A0A8M9PMG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13966", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13966", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13966:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13966:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01223", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01223", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021328243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328243", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PMG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMKTVSRGDSMLTPPRREDPPDNYLDDMAECLLFYFNRFQWLEVKNEIEETCDIKNQHLWSNEDIKKASDETERMVKKHDPKVKQWACVVTFQIKQRLDYEKHKTSETQSSLTDAAQPFGTVTPDLSHRPAGRASQRGYSAIGIKIPLSELFGHEATSEQAVTVPSEYKLTDGCPSRRQITRKKSYVSSYNENTNNPDWVFEILNKQTLAQNYTGTGRFPECEIGKDYNKGHLSAARNNRWSKQAFEDTFDLINMSPQLAELNNCMWKSLEHRCRKKAKDNNIRNLHVYTGTIILESGSVGQSGNKKAVPDYFYKVIIEETDGTVSKPVCYLIYNDKDKIKHDLETREHGQDFLTQRYRIHIENTENENIGNIEHTEKTEDIKNIKRIIGKIFVRPAQMYTDEIRSVTWTGEGDGETLHSVHIEVRMSIPK", "length": 431, "header": "tr|A0A8M9PMG3-1|A0A8M9PMG3_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC101885345 PE=3 SV=2 CANONICAL=A0A8M9PMG3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PMG3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3/entry#A0A8M9PMG3-1", "sequence": { "sequence": "MMKTVSRGDSMLTPPRREDPPDNYLDDMAECLLFYFNRFQWLEVKNEIEETCDIKNQHLWSNEDIKKASDETERMVKKHDPKVKQWACVVTFQIKQRLDYEKHKTSETQSSLTDAAQPFGTVTPDLSHRPAGRASQRGYSAIGIKIPLSELFGHEATSEQAVTVPSEYKLTDGCPSRRQITRKKSYVSSYNENTNNPDWVFEILNKQTLAQNYTGTGRFPECEIGKDYNKGHLSAARNNRWSKQAFEDTFDLINMSPQLAELNNCMWKSLEHRCRKKAKDNNIRNLHVYTGTIILESGSVGQSGNKKAVPDYFYKVIIEETDGTVSKPVCYLIYNDKDKIKHDLETREHGQDFLTQRYRIHIENTENENIGNIEHTEKTEDIKNIKRIIGKIFVRPAQMYTDEIRSVTWTGEGDGETLHSVHIEVRMSIPK", "length": 431, "header": "tr|A0A8M9PMG3-1|A0A8M9PMG3_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC101885345 PE=3 SV=2 CANONICAL=A0A8M9PMG3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885345", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885345", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3" } ], "pmid": "" }, { "name": "mitochondrial inner membrane", "id": "GO:0005743", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005743", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3" } ], "pmid": "" }, { "name": "RNA endonuclease activity", "id": "GO:0004521", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004521", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3" } ], "pmid": "" }, { "name": "single-stranded DNA endodeoxyribonuclease activity", "id": "GO:0000014", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000014", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "apoptotic DNA fragmentation", "id": "GO:0006309", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006309", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMG3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PMG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3" }, { "id": "SM00892", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00892" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase", "eco_id": "ECO_0000259", "start_pos": 182, "end_pos": 360, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PMG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3" }, { "id": "SM00477", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00477" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ENPP1-3/EXOG-like endonuclease/phosphodiesterase", "eco_id": "ECO_0000259", "start_pos": 183, "end_pos": 360, "start_aa": "Lys", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [ { "evidence": [ { "id": "A0A8M9PMG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3#function" }, { "id": "A0A8M9PMG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMG3" }, { "id": "PIRSR640255-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR640255-2" } ], "binding_site_uniprot": 263, "amino_acid": "Asn", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "catalytic", "eco_id": "ECO_0000256", "start_pos": 263, "end_pos": 263, "start_aa": "Asn", "end_aa": "Asn", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 212, "end_pos": 214 }, { "start_pos": 254, "end_pos": 256 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PMI0-1", "uniprot_ac": "A0A8M9PMI0", "uniprot_id": "A0A8M9PMI0_DANRE", "mass": { "chemical_mass": 36070.0, "monoisotopic_mass": 36070.0 }, "refseq": { "ac": "NP_001313414", "name": "uncharacterized protein LOC562659", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313414" }, "gene_names": [ { "name": "si:ch211-197h24.9", "type": "recommended", "evidence": [ { "id": "A0A8M9PMI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMI0" } ] }, { "name": "sb:cb975", "type": "synonym", "evidence": [ { "id": "NP_001313414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313414" }, { "id": "A0A8M9PMI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMI0" } ] }, { "name": "si:ch211-197h24.9", "type": "synonym", "evidence": [ { "id": "NP_001313414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313414" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC562659", "type": "synonym", "evidence": [ { "id": "A0A8M9PMI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMI0/entry#names_and_taxonomy" } ] }, { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PMI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMI0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC562659", "type": "synonym", "evidence": [ { "id": "NP_001313414", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313414" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CN167329.1, CA474316.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1 and EB918552.1. On May 19, 2016 this sequence version replaced XP_706145.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001313414", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313414" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMI0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMI0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-197h24.9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMI0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-031116-15", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-031116-15", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "562659", "url": "https://www.ncbi.nlm.nih.gov/gene/562659", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:562659", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562659", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FHEAKTI", "url": "https://omabrowser.org/oma/group/FHEAKTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PMI0", "url": "https://www.orthodb.org/?gene=A0A8M9PMI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001313414", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313414", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PMI0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PMI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HGX8", "url": "https://www.uniprot.org/uniprotkb/A0AC58HGX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HGX8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HGX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-031116-15", "url": "https://zfin.org/ZDB-GENE-031116-15", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKRRNNRNVTETYFEGEHLSLADLKKESVENGYLFKHNIPAYPKSVKFHVDKVSHVTGECGVRGIFTDSGFRQPPELVDNDENYFLWWDLSVTSDEISSAEEDFLMSLFPRRSAAQIRNQSPFLKQFTSSKAFQKDSSYGNFRFTFSLKELLWHYGDQFCGGHSPVLRVYETALYRREIVYKIVVHPRDKNHLYESYPRLPDQGDGVCGYHDGAMWWRCQAPSETYKLKLDVNRFDKNVSVSFHYKEEYYVWDHVCVAFHMEPNWVLHVNQDRLLKKVTVCEVIPPCLLRPPETPLSLNEARHVLASI", "length": 308, "header": "tr|A0A8M9PMI0-1|A0A8M9PMI0_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-197h24.9 PE=4 SV=1 CANONICAL=A0A8M9PMI0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PMI0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMI0/entry#A0A8M9PMI0-1", "sequence": { "sequence": "MKRRNNRNVTETYFEGEHLSLADLKKESVENGYLFKHNIPAYPKSVKFHVDKVSHVTGECGVRGIFTDSGFRQPPELVDNDENYFLWWDLSVTSDEISSAEEDFLMSLFPRRSAAQIRNQSPFLKQFTSSKAFQKDSSYGNFRFTFSLKELLWHYGDQFCGGHSPVLRVYETALYRREIVYKIVVHPRDKNHLYESYPRLPDQGDGVCGYHDGAMWWRCQAPSETYKLKLDVNRFDKNVSVSFHYKEEYYVWDHVCVAFHMEPNWVLHVNQDRLLKKVTVCEVIPPCLLRPPETPLSLNEARHVLASI", "length": 308, "header": "tr|A0A8M9PMI0-1|A0A8M9PMI0_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-197h24.9 PE=4 SV=1 CANONICAL=A0A8M9PMI0-1" }, "locus": {} }, { "isoform_ac": "A0AC58HGX8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMI0/entry#A0AC58HGX8-1", "sequence": { "sequence": "MGECGVRGIFTDSGFRQPPELVDNDENYFLWWDLSVTSDEISSAEEDFLMSLFPRRSAAQIRNQSPFLKQFTSSKAFQKDSSYGNFRFTFSLKELLWHYGDQFCGGHSPVLRVYETALYRREIVYKIVVHPRDKNHLYESYPRLPDQGDGVCGYHDGAMWWRCQAPSETYKLKLDVNRFDKNVSVSFHYKEEYYVWDHVCVAFHMEPNWVLHVNQDRLLKKVTVCEVIPPCLLRPPETPLSLNEARHVLASI", "length": 252, "header": "tr|A0AC58HGX8-1|A0AC58HGX8_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=si:ch211-197h24.9 PE=4 SV=1 CANONICAL=A0A8M9PMI0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Hematopoietic gene expression profile in zebrafish kidney marrow.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2004", "authors": "Song Huai-Dong, Sun Xiao-Jian, Deng Min, Zhang Guo-Wei, Zhou Yi, Wu Xin-Yan, Sheng Yan, Chen Yi, Ruan Zheng, Jiang Chun-Lei, Fan Hui-Yong, Zon Leonard I, Kanki John P, Liu Ting Xi, Look A Thomas, Chen Zhu", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMI0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMI0" } ], "reference": [ { "type": "PubMed", "id": "15520368", "url": "https://glygen.org/publication/PubMed/15520368" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMI0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMI0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:562659", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562659", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 238, "end_pos": 240, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 238, "end_pos": 240 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PML3-1", "uniprot_ac": "A0A8M9PML3", "uniprot_id": "A0A8M9PML3_DANRE", "mass": { "chemical_mass": 37018.0, "monoisotopic_mass": 37018.0 }, "refseq": { "ac": "XP_073809877", "name": "trans-3-hydroxy-L-proline dehydratase isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073809877" }, "gene_names": [ { "name": "l3hypdh", "type": "recommended", "evidence": [ { "id": "A0A8M9PML3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3" } ] }, { "name": "l3hypdh", "type": "synonym", "evidence": [ { "id": "XP_073809877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073809877" } ] } ], "protein_names": [ { "name": "trans-L-3-hydroxyproline dehydratase", "type": "recommended", "evidence": [ { "id": "A0A8M9PML3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3/entry#names_and_taxonomy" } ] }, { "name": "4.2.1.77", "type": "synonym", "evidence": [ { "id": "A0A8M9PML3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3/entry#names_and_taxonomy" } ] }, { "name": "trans-3-hydroxy-L-proline dehydratase isoform X1", "type": "synonym", "evidence": [ { "id": "XP_073809877", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073809877" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073809877", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073809877" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PML3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "l3hypdh", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-170412-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-170412-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PML3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PML3", "database": "AlphaFoldDB", "categories": [] }, { "id": "565785", "url": "https://www.ncbi.nlm.nih.gov/gene/565785", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008794", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008794", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565785", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565785", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SHVLWTG", "url": "https://omabrowser.org/oma/group/SHVLWTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PML3", "url": "https://www.orthodb.org/?gene=A0A8M9PML3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33442", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33442", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33442:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33442:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05544", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05544", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073809877", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073809877", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "10320", "url": "https://www.rhea-db.org/rhea/10320", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PML3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PML3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTR6", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTR6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-170412-1", "url": "https://zfin.org/ZDB-GENE-170412-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAFPKLPPHCGSVLSVVDMHTGGEPLRIILSGFPEVQGDTILAKRRYVREHLDHLRKVLMLEPRGHNDMYGALLVKSELAEADLGVLFLHNEGYSTMCGHAVIALGRFAVDYGLVKEPSSPETQINIHCPCGLVKAFTQYADGKTGAVRFHSVPAFAFATDVSVSVEGYGTVTVDISYGGALYAFVSAEKFGSDVNKSKTRDLVDAATAVSEAVKSQVKLYHPVSEDLAFLYGTILTDGKDAFSEEPTANMCVFADAQVDRSPTGSGVTARVALQYHKGLIRLNQTRSFQSGATGSVFTGTAIEETTCGDFKAVVVEVKGHAHYSGVATFTQESDDPLSGGFLLR", "length": 345, "header": "tr|A0A8M9PML3-1|A0A8M9PML3_DANRE Isoform 1 of trans-L-3-hydroxyproline dehydratase OS=Danio rerio OX=7955 GN=l3hypdh PE=3 SV=2 CANONICAL=A0A8M9PML3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PML3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3/entry#A0A8M9PML3-1", "sequence": { "sequence": "MAFPKLPPHCGSVLSVVDMHTGGEPLRIILSGFPEVQGDTILAKRRYVREHLDHLRKVLMLEPRGHNDMYGALLVKSELAEADLGVLFLHNEGYSTMCGHAVIALGRFAVDYGLVKEPSSPETQINIHCPCGLVKAFTQYADGKTGAVRFHSVPAFAFATDVSVSVEGYGTVTVDISYGGALYAFVSAEKFGSDVNKSKTRDLVDAATAVSEAVKSQVKLYHPVSEDLAFLYGTILTDGKDAFSEEPTANMCVFADAQVDRSPTGSGVTARVALQYHKGLIRLNQTRSFQSGATGSVFTGTAIEETTCGDFKAVVVEVKGHAHYSGVATFTQESDDPLSGGFLLR", "length": 345, "header": "tr|A0A8M9PML3-1|A0A8M9PML3_DANRE Isoform 1 of trans-L-3-hydroxyproline dehydratase OS=Danio rerio OX=7955 GN=l3hypdh PE=3 SV=2 CANONICAL=A0A8M9PML3-1" }, "locus": {} }, { "isoform_ac": "A0AC58JTR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3/entry#A0AC58JTR6-1", "sequence": { "sequence": "MCGHAVIALGRFAVDYGLVKEPSSPETQINIHCPCGLVKAFTQYADGKTGAVRFHSVPAFAFATDVSVSVEGYGTVTVDISYGGALYAFVSAEKFGSDVNKSKTRDLVDAATAVSEAVKSQVKLYHPVSEDLAFLYGTILTDGKDAFSEEPTANMCVFADAQVDRSPTGSGVTARVALQYHKGLIRLNQTRSFQSGATGSVFTGTAIEETTCGDFKAVVVEVKGHAHYSGVATFTQESDDPLSGGFLLR", "length": 249, "header": "tr|A0AC58JTR6-1|A0AC58JTR6_DANRE Computationally mapped isoform of trans-L-3-hydroxyproline dehydratase OS=Danio rerio OX=7955 GN=l3hypdh PE=3 SV=1 CANONICAL=A0A8M9PML3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "dre:565785", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565785", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZTS1-1", "protein_name": "trans-L-3-hydroxyproline dehydratase", "gene_name": "L3HYPDH", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MASRLPVAQLPPHDPGTPALSVVDMHTGGEPLRIVLAGCPEVAGPTLLAKRRYMRQHLDYVRRRLMFEPRGHRDMYGAVLVPSELPEAHLGVLFLHNEGYSSMCGHAVLALGRFALDYGLVSAPPTGAREALVNIHCPCGLVTAFVECEGGRSRGPVRFHSVPAFALATDLLVDVPGRGKVVVDIAYGGAFYAFVSAEKLGLDVCSSKTRDLVDAASAVTEAVKAQFKINHPDSEDLAFLYGTILTDGKDTYSEEPTTNICVFADEQVDRSPTGSGVTARIALQYHKGLLKLNQTRAFKSSATSSIFTGKAVRETKCGDFKAVIVEVSGQAHYTGTASFIVEDDDPLRDGFLLK", "length": 354 }, "evidence": [ { "id": "A0A8M9PML3", "url": "https://omabrowser.org/oma/group/A0A8M9PML3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q3SX04-1", "protein_name": "Trans-L-3-hydroxyproline dehydratase", "gene_name": "L3HYPDH", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGPLTVPWMPPHDPGTPALSVVDMHTGGEPLRIVLAGCPEVVGPTLLAKRRYMRQHLDHVRRRLMFEPRGHRDMYGAVLVPSELPDAHLGVLFLNNEGYSSMCGHAVLALGRFALDFGLVPAPPSDAQEALVNIHCPCGLVAAFVECEGCRSRGPVRFHSVPAFVLATDFLVDVPGRGKVVVDIAYGGAFYAFVSAEKLGLDVCSAKMGDLVAAASAVTEAVKAQFKISHPDSEDLAFLYGTILTDGKDTYNEEPTTNICVFADEQVDRSPTGSGVTARIALQYHKGLLELNQTRAFKSSATGSVFTGKAVREAKCGDFKAVIVEVSGQAHYTGTASFIVEDDDPLRDGFLLK", "length": 354 }, "evidence": [ { "id": "A0A8M9PML3", "url": "https://omabrowser.org/oma/group/A0A8M9PML3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96EM0-1", "protein_name": "Trans-3-hydroxy-L-proline dehydratase", "gene_name": "L3HYPDH", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESALAVPRLPPHDPGTPVLSVVDMHTGGEPLRIVLAGCPEVSGPTLLAKRRYMRQHLDHVRRRLMFEPRGHRDMYGAVLVPSELPDAHLGVLFLHNEGYSSMCGHAVLALGRFALDFGLVPAPPAGTREARVNIHCPCGLVTAFVACEDGRSHGPVRFHSVPAFVLATDLMVDVPGHGKVMVDIAYGGAFYAFVTAEKLGLDICSAKTRDLVDAASAVTEAVKAQFKINHPDSEDLAFLYGTILTDGKDAYTKEPTTNICVFADEQVDRSPTGSGVTARIALQYHKGLLELNQMRAFKSSATGSVFTGKAVREAKCGDFKAVIVEVSGQAHYTGTASFIIEDDDPLRDGFLLK", "length": 354 }, "evidence": [ { "id": "A0A8M9PML3", "url": "https://omabrowser.org/oma/group/A0A8M9PML3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CXA2-1", "protein_name": "Trans-L-3-hydroxyproline dehydratase", "gene_name": "L3hypdh", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAALAVTRLPPNDPRTPALSVVDMHTGGEPLRIVHAGCPEVAGPTLLAKRRYMRQHLDYIRRRLVFEPRGHRDMYGAILVPSELPDAHLGVLFLHNEGYSSMCGHAVLALGRFALDFGLVPAPPKGAREAQVNIHCPCGLVTAFVECEGGRSCGPVRFHSVPAFVLASDLTVDVPGHGKVLVDIAYGGAFYAFVSAEKLGLDVCSAKTRDLVDAASALTGAVKAQFKINHPESEDLGFLYGSILTDGKDAYSEEATTNICVFADEQVDRSPTGSGVTARIALQYHKGLLQLNQTRAFKSSATGSVFTGCAVREAKCGDFKAVIVEVAGQAHYTGTANLTVEDGDPLRDGFLLK", "length": 354 }, "evidence": [ { "id": "A0A8M9PML3", "url": "https://omabrowser.org/oma/group/A0A8M9PML3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "trans-L-3-hydroxyproline dehydratase activity", "id": "GO:0050346", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050346", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PML3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3" } ], "pmid": "" }, { "name": "hydro-lyase activity", "id": "GO:0016836", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016836", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PML3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "10320", "name": "", "equation": "trans-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0A8M9PML3-1" ], "evidence": [ { "id": "10320", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/10320" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8M9PML3", "gene_name": "l3hypdh", "activity": [ { "ec_number": "4.2.1.77", "activity": "trans-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O.", "evidence": [ { "id": "A0A8M9PML3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3" } ] }, { "ec_number": "4.2.1.77", "activity": "", "evidence": [ { "id": "A0A8M9PML3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.2.1.77", "ec_name": "trans-3-hydroxy-L-proline = 1-pyrroline-2-carboxylate + H2O.", "evidence": [ { "id": "4.2.1.77", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.2.1.77" }, { "id": "4.2.1.77", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.2.1.77" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 196, "end_pos": 198 }, { "start_pos": 284, "end_pos": 286 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PML6-1", "uniprot_ac": "A0A8M9PML6", "uniprot_id": "A0A8M9PML6_DANRE", "mass": { "chemical_mass": 68164.0, "monoisotopic_mass": 68164.0 }, "refseq": { "ac": "XP_021323511", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323511" }, "gene_names": [ { "name": "LOC110438103", "type": "recommended", "evidence": [ { "id": "A0A8M9PML6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML6" } ] }, { "name": "LOC110438103", "type": "synonym", "evidence": [ { "id": "XP_021323511", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323511" } ] } ], "protein_names": [ { "name": "Crestin", "type": "recommended", "evidence": [ { "id": "A0A8M9PML6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021323511", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323511" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323511", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323511" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PML6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438103", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML6", "locus": {} } ], "crossref": [ { "id": "A0A8M9PML6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PML6", "database": "AlphaFoldDB", "categories": [] }, { "id": "110438103", "url": "https://www.ncbi.nlm.nih.gov/gene/110438103", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:110438103", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438103", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PML6", "url": "https://www.orthodb.org/?gene=A0A8M9PML6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_021323511", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323511", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PML6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PML6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MARPKDPVRHWKDLEAWLSVATDSLLPKAAETLQHLTQDQLDENLNSLMKQDPSKSYNHKDLAKITGTLSHVLIATLKLSDWHSAQLQHKLTHVQTRINQLELEAQERPEQPDETDQTAKEEIDKLQETLAATTQEMEQAKADQADVANKLEYVEQLLEEVNADSKDKDSRIKALETHLSEARHEVRRLTQQLDYIKEESNSTKDELKHAYELTHNEKAEGSLPKPSPSPSVPDNHVSPFGLDLRDLDKLVKNLGKFTPNLPGSQDVHAYLQDIDFHLEMRPNVTNKDRLYLLRATSSPEVRSFLDRQPAHTKTDYLLLREALIREFDDIESEQGLVAALETKQGRHESSQAYYSRLRRAYFGTRNEPEMEEDLNFKILFLRNLHPGVSHHLGVLACPHTMNTQQLRDLAHKAYVKQKTASEKSAKIPAVYDFNTQSQDLALEGAQGPDNARLPPSEWNVSSYNRQRDCHADTRPKQWNRRWKGLSGRQHSPERHRERPWNRSTSFVNQRGTSSWESSGTSKVKQPHLDATSPRGQRKNSQRFHADQAPTESPQGTTSPCFDPQELMKMILKEFFQRREADRKWQRKGKPDSA", "length": 593, "header": "tr|A0A8M9PML6-1|A0A8M9PML6_DANRE Isoform 1 of Crestin OS=Danio rerio OX=7955 GN=LOC110438103 PE=4 SV=1 CANONICAL=A0A8M9PML6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PML6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PML6/entry#A0A8M9PML6-1", "sequence": { "sequence": "MARPKDPVRHWKDLEAWLSVATDSLLPKAAETLQHLTQDQLDENLNSLMKQDPSKSYNHKDLAKITGTLSHVLIATLKLSDWHSAQLQHKLTHVQTRINQLELEAQERPEQPDETDQTAKEEIDKLQETLAATTQEMEQAKADQADVANKLEYVEQLLEEVNADSKDKDSRIKALETHLSEARHEVRRLTQQLDYIKEESNSTKDELKHAYELTHNEKAEGSLPKPSPSPSVPDNHVSPFGLDLRDLDKLVKNLGKFTPNLPGSQDVHAYLQDIDFHLEMRPNVTNKDRLYLLRATSSPEVRSFLDRQPAHTKTDYLLLREALIREFDDIESEQGLVAALETKQGRHESSQAYYSRLRRAYFGTRNEPEMEEDLNFKILFLRNLHPGVSHHLGVLACPHTMNTQQLRDLAHKAYVKQKTASEKSAKIPAVYDFNTQSQDLALEGAQGPDNARLPPSEWNVSSYNRQRDCHADTRPKQWNRRWKGLSGRQHSPERHRERPWNRSTSFVNQRGTSSWESSGTSKVKQPHLDATSPRGQRKNSQRFHADQAPTESPQGTTSPCFDPQELMKMILKEFFQRREADRKWQRKGKPDSA", "length": 593, "header": "tr|A0A8M9PML6-1|A0A8M9PML6_DANRE Isoform 1 of Crestin OS=Danio rerio OX=7955 GN=LOC110438103 PE=4 SV=1 CANONICAL=A0A8M9PML6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110438103", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438103", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 201, "end_pos": 203, "annotation": "n_glycosylation_sequon" }, { "start_pos": 283, "end_pos": 285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 501, "end_pos": 503, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 201, "end_pos": 203 }, { "start_pos": 283, "end_pos": 285 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 501, "end_pos": 503 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PMN9-1", "uniprot_ac": "A0A8M9PMN9", "uniprot_id": "A0A8M9PMN9_DANRE", "mass": { "chemical_mass": 30805.0, "monoisotopic_mass": 30805.0 }, "refseq": { "ac": "NP_001429825", "name": "B-cell receptor CD22-like precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429825" }, "gene_names": [ { "name": "LOC100535079", "type": "recommended", "evidence": [ { "id": "A0A8M9PMN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMN9" } ] }, { "name": "LOC100535079", "type": "synonym", "evidence": [ { "id": "NP_001429825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429825" } ] } ], "protein_names": [ { "name": "B-cell receptor CD22-like isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PMN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMN9/entry#names_and_taxonomy" } ] }, { "name": "B-cell receptor CD22-like precursor", "type": "synonym", "evidence": [ { "id": "NP_001429825", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429825" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588717.10205837.1, SRR32588718.33534978.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505375 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PMR9-1", "uniprot_ac": "A0A8M9PMR9", "uniprot_id": "A0A8M9PMR9_DANRE", "mass": { "chemical_mass": 12163.0, "monoisotopic_mass": 12163.0 }, "refseq": { "ac": "XP_021332782", "name": "exosome complex exonuclease RRP44", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332782" }, "gene_names": [ { "name": "LOC103911231", "type": "recommended", "evidence": [ { "id": "A0A8M9PMR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMR9" } ] }, { "name": "LOC103911231", "type": "synonym", "evidence": [ { "id": "XP_021332782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332782" } ] } ], "protein_names": [ { "name": "Exosome complex exonuclease RRP44", "type": "synonym", "evidence": [ { "id": "A0A8M9PMR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMR9/entry#names_and_taxonomy" } ] }, { "name": "exosome complex exonuclease RRP44", "type": "synonym", "evidence": [ { "id": "XP_021332782", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332782" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021332782", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332782" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMR9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMR9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC103911231", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMR9", "locus": {} } ], "crossref": [ { "id": "103911231", "url": "https://www.ncbi.nlm.nih.gov/gene/103911231", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:103911231", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103911231", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PMR9", "url": "https://www.orthodb.org/?gene=A0A8M9PMR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_021332782", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021332782", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PMR9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PMR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMR9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLKSKTFVKKTRSGGVLKIVREHYLRDDIWCGSEVCKECKDEAPVLQEETCIESNLCPYPHYLIPDTNVVLHQQFRCRVWCFNPKIYNEGSIKLTEHQLKFGTT", "length": 104, "header": "tr|A0A8M9PMR9-1|A0A8M9PMR9_DANRE Isoform 1 of Exosome complex exonuclease RRP44 OS=Danio rerio OX=7955 GN=LOC103911231 PE=4 SV=1 CANONICAL=A0A8M9PMR9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PMR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMR9/entry#A0A8M9PMR9-1", "sequence": { "sequence": "MLKSKTFVKKTRSGGVLKIVREHYLRDDIWCGSEVCKECKDEAPVLQEETCIESNLCPYPHYLIPDTNVVLHQQFRCRVWCFNPKIYNEGSIKLTEHQLKFGTT", "length": 104, "header": "tr|A0A8M9PMR9-1|A0A8M9PMR9_DANRE Isoform 1 of Exosome complex exonuclease RRP44 OS=Danio rerio OX=7955 GN=LOC103911231 PE=4 SV=1 CANONICAL=A0A8M9PMR9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103911231", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103911231", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "exonuclease activity", "id": "GO:0004527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004527", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMR9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMR9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PMY1-1", "uniprot_ac": "A0A8M9PMY1", "uniprot_id": "A0A8M9PMY1_DANRE", "mass": { "chemical_mass": 19235.0, "monoisotopic_mass": 19235.0 }, "refseq": { "ac": "XP_073798770", "name": "calmodulin-like protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073798770" }, "gene_names": [ { "name": "calml4b", "type": "recommended", "evidence": [ { "id": "A0A8M9PMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1" } ] }, { "name": "calml4b", "type": "synonym", "evidence": [ { "id": "XP_073798770", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073798770" } ] } ], "protein_names": [ { "name": "Calmodulin", "type": "recommended", "evidence": [ { "id": "A0A8M9PMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1/entry#names_and_taxonomy" } ] }, { "name": "calmodulin-like protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_073798770", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073798770" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073798770", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073798770" } ] }, { "annotation": "Calmodulin acts as part of a calcium signal transduction pathway by mediating the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Calcium-binding is required for the activation of calmodulin. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases, such as myosin light-chain kinases and calmodulin-dependent protein kinase type II (CaMK2), and phosphatases.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMY1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1#function" }, { "database": "UniProtKB", "id": "ARBA00037485", "url": "https://www.uniprot.org/uniprotkb/ARBA00037485#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMY1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "calml4b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-071009-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071009-6", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00051", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00051", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100321746", "url": "https://www.ncbi.nlm.nih.gov/gene/100321746", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050230", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050230", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100321746", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100321746", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR23048", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23048", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23048:SF45", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23048:SF45", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13499", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13499", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073798770", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073798770", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PMY1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PMY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IX31", "url": 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CANONICAL=A0A8M9PMY1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PMY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1/entry#A0A8M9PMY1-1", "sequence": { "sequence": "MAKFLSQDQINEYKECFSLYDQKRKGKLKVQDLLTVMRSLGCCPTLPELHRHLLSHKIDKHGELDFSTFLSIMHEQIQQENPRAEILQAVRLTDTEKRGFITAAELRARLTHFGEKLRDQEVDELLSEAGVANDGQIKYEDCERIVTLLTRRRDEPLIPRQDSSAV", "length": 166, "header": "tr|A0A8M9PMY1-1|A0A8M9PMY1_DANRE Isoform 1 of Calmodulin OS=Danio rerio OX=7955 GN=calml4b PE=3 SV=2 CANONICAL=A0A8M9PMY1-1" }, "locus": {} }, { "isoform_ac": "A0AC58IX31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1/entry#A0AC58IX31-1", "sequence": { "sequence": "MAKFLSQDQINDKHGELDFSTFLSIMHEQIQQENPRAEILQAVRLTDTEKRGFITAAELRARLTHFGEKLRDQEVDELLSEAGVANDGQIKYEDCERIVTLLTRRRDEPLIPRQDSSAV", "length": 119, "header": "tr|A0AC58IX31-1|A0AC58IX31_DANRE Computationally mapped isoform of Calmodulin-like protein 4 isoform X3 OS=Danio rerio OX=7955 GN=calml4b PE=4 SV=1 CANONICAL=A0A8M9PMY1-1" }, "locus": {} }, { "isoform_ac": "A0AC58IX35-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1/entry#A0AC58IX35-1", "sequence": { "sequence": "MRSLGCCPTLPELHRHLLSHKIDKHGELDFSTFLSIMHEQIQQENPRAEILQAVRLTDTEKRGFITAAELRARLTHFGEKLRDQEVDELLSEAGVANDGQIKYEDCERIVTLLTRRRDEPLIPRQDSSAV", "length": 130, "header": "tr|A0AC58IX35-1|A0AC58IX35_DANRE Computationally mapped isoform of Calmodulin-like protein 4 isoform X2 OS=Danio rerio OX=7955 GN=calml4b PE=4 SV=1 CANONICAL=A0A8M9PMY1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100321746", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100321746", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F7F9Q8-1", "protein_name": "Calmodulin-like protein 4", "gene_name": "Calml4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVGASAVQLQSDSRGIGPSLHGSRGFITRPPPSLVDFRLQAGVKRTKHSSRSQGCLRMAKFLSQEQINEYKECFSLYDKQQRGKIKATDLLVSMRCLGASPTPGEVQRHLQTHGIDKNGELDFSTFLTIMHMQIKQEDPKKEILLAMLMTDKEKKGYIMASELRSKLMKLGEKLTHKEVDELFKEAGIEPNGQVKYDTFIQRITLPVRDY", "length": 210 }, "evidence": [ { "id": "HGNC:18445", "url": "https://alliancegenome.org/gene/HGNC:18445#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071009-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071009-6#orthology", "database": "AGR" }, { "id": "MGI:1922850", "url": "https://alliancegenome.org/gene/MGI:1922850#orthology", "database": "AGR" }, { "id": "RGD:1583918", "url": "https://alliancegenome.org/gene/RGD:1583918#orthology", "database": "AGR" }, { "id": "FB:FBgn0038830", "url": "https://alliancegenome.org/gene/FB:FBgn0038830#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q91WQ9-1", "protein_name": "Calmodulin-like protein 4", "gene_name": "Calml4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKFLSQDQINEYKECFSLYDKQQRGKIKATDLLVSMRCLGASPTPGEVQRHLQTHGIDKNGELDFSTFLTIMHMQIKQEDPKKEILLAMLMADKEKKGYIMASELRSKLMKLGEKLTHKEVDDLFKEAGIEPNGQVKYDTFIQRITIPVRDY", "length": 153 }, "evidence": [ { "id": "HGNC:18445", "url": "https://alliancegenome.org/gene/HGNC:18445#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071009-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071009-6#orthology", "database": "AGR" }, { "id": "MGI:1922850", "url": "https://alliancegenome.org/gene/MGI:1922850#orthology", "database": "AGR" }, { "id": "RGD:1583918", "url": "https://alliancegenome.org/gene/RGD:1583918#orthology", "database": "AGR" }, { "id": "FB:FBgn0038830", "url": "https://alliancegenome.org/gene/FB:FBgn0038830#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96GE6-1", "protein_name": "Calmodulin-like protein 4", "gene_name": "CALML4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAEHLLPGPPPSLADFRLEAGGKGTERGSGSSKPTGSSRGPRMAKFLSQDQINEYKECFSLYDKQQRGKIKATDLMVAMRCLGASPTPGEVQRHLQTHGIDGNGELDFSTFLTIMHMQIKQEDPKKEILLAMLMVDKEKKGYVMASDLRSKLTSLGEKLTHKEVDDLFREADIEPNGKVKYDEFIHKITLPGRDY", "length": 196 }, "evidence": [ { "id": "HGNC:18445", "url": "https://alliancegenome.org/gene/HGNC:18445#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071009-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071009-6#orthology", "database": "AGR" }, { "id": "MGI:1922850", "url": "https://alliancegenome.org/gene/MGI:1922850#orthology", "database": "AGR" }, { "id": "RGD:1583918", "url": "https://alliancegenome.org/gene/RGD:1583918#orthology", "database": "AGR" }, { "id": "FB:FBgn0038830", "url": "https://alliancegenome.org/gene/FB:FBgn0038830#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VDI3-1", "protein_name": "Myosin-2 essential light chain", "gene_name": "Dmel\\CG17272", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARYFKEQDIDEFRECFYLFARSGQINNLDELTVIMRSLGLSPTIQELVSYLKQKNGKMSFADFLDIMHQHSKVESLPDEVIAAFKAADPQNKGTISARQLRNLLQNWGEGLSMREVDNIFREANVNNNSTVRYADFVKIACAPVPDYY", "length": 149 }, "evidence": [ { "id": "HGNC:18445", "url": "https://alliancegenome.org/gene/HGNC:18445#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071009-6", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071009-6#orthology", "database": "AGR" }, { "id": "MGI:1922850", "url": "https://alliancegenome.org/gene/MGI:1922850#orthology", "database": "AGR" }, { "id": "RGD:1583918", "url": "https://alliancegenome.org/gene/RGD:1583918#orthology", "database": "AGR" }, { "id": "FB:FBgn0038830", "url": "https://alliancegenome.org/gene/FB:FBgn0038830#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMY1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMY1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1" } ], "pmid": "" }, { "name": "enzyme regulator activity", "id": "GO:0030234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030234", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMY1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "microtubule cytoskeleton organization", "id": "GO:0000226", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000226", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMY1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PMY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY1" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 43, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PMY8-1", "uniprot_ac": "A0A8M9PMY8", "uniprot_id": "A0A8M9PMY8_DANRE", "mass": { "chemical_mass": 49266.0, "monoisotopic_mass": 49266.0 }, "refseq": { "ac": "XP_021322565", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322565" }, "gene_names": [ { "name": "LOC101883025", "type": "recommended", "evidence": [ { "id": "A0A8M9PMY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY8" } ] }, { "name": "LOC101883025", "type": "synonym", "evidence": [ { "id": "XP_021322565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322565" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PMY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322565", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322565" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322565" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMY8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101883025", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY8", "locus": {} } ], "crossref": [ { "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101883025", "url": "https://www.ncbi.nlm.nih.gov/gene/101883025", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101883025", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101883025", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PMY8", "url": "https://www.orthodb.org/?gene=A0A8M9PMY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322565", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322565", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PMY8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PMY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHP7", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHP7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHP7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIMLFDLLAVLGMLSLTGDSSQGCCSSSQISQQYHFINITKNWTEAQRFCREKYTGLVTVKNGDETKTITDVLNDVYIGLYRQERFSWHWCMPDTFYNAKTLQNWKKEQPDENNKGFETGTNNSNSERQFVCYTARNNTQIQIEKREFKRGAQQSCKNFTDLKNSSISLENSILIVLKNYNWGFITNDVWIGLFKDDCLWLDQNNSCFCACSLSPEKHNNSSSNKCKWIVNEKSIRNEAQCNENLPFICYDDLKRTATPDPLPTPTAGENITTSGTTTQQHKPNQNAIEREHANSQTTQILPTGQEQDNLILVNDNLTWTEAVSYCRKNHVDLISIHSEKLQNRAARKAIQASSSHVWIGLRYTCNFSFWFWINNREAGCYQNWVSGHGPHGFVECGLSGAMESNGWHRWIGRPESDRLNFICHTYTG", "length": 429, "header": "tr|A0A8M9PMY8-1|A0A8M9PMY8_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101883025 PE=4 SV=1 CANONICAL=A0A8M9PMY8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PMY8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY8/entry#A0A8M9PMY8-1", "sequence": { "sequence": "MNIMLFDLLAVLGMLSLTGDSSQGCCSSSQISQQYHFINITKNWTEAQRFCREKYTGLVTVKNGDETKTITDVLNDVYIGLYRQERFSWHWCMPDTFYNAKTLQNWKKEQPDENNKGFETGTNNSNSERQFVCYTARNNTQIQIEKREFKRGAQQSCKNFTDLKNSSISLENSILIVLKNYNWGFITNDVWIGLFKDDCLWLDQNNSCFCACSLSPEKHNNSSSNKCKWIVNEKSIRNEAQCNENLPFICYDDLKRTATPDPLPTPTAGENITTSGTTTQQHKPNQNAIEREHANSQTTQILPTGQEQDNLILVNDNLTWTEAVSYCRKNHVDLISIHSEKLQNRAARKAIQASSSHVWIGLRYTCNFSFWFWINNREAGCYQNWVSGHGPHGFVECGLSGAMESNGWHRWIGRPESDRLNFICHTYTG", "length": 429, "header": "tr|A0A8M9PMY8-1|A0A8M9PMY8_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101883025 PE=4 SV=1 CANONICAL=A0A8M9PMY8-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHP7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY8/entry#A0AC58HHP7-1", "sequence": { "sequence": "MNIMLFDLLAVLGMLSLTGDSSQGCCSSSQISQQYHFINITKNWTEAQRFCREKYTGLVTVKNGDETKTITDVLNDVYIGLYRQERFSWHWCMPDTFYNAKTLQNWKKEQPDENNKGFETGTNNSNSERQFVCYTARNNTQIQIEKREFKRGAQQSCKNFTDLKNSSISLENSILIVLKNYNWGFITNDVWIGLFKDDCLWLDQNNSCFCACSLSPEKHNNSSSNKCKWIVNEKSIRNEAQCNENLPFICYDDLKRTATPDPLPTPTAGENITTSGTTTQQHKPNQNAIEREHANSQTTQILPTGQEQADSSL", "length": 313, "header": "tr|A0AC58HHP7-1|A0AC58HHP7_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC101883025 PE=4 SV=1 CANONICAL=A0A8M9PMY8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 265, "start_aa": "Thr", "end_pos": 265, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr265", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 267, "start_aa": "Thr", "end_pos": 267, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr267", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101883025", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101883025", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 271, "end_pos": 273, "annotation": "n_glycosylation_sequon" }, { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" }, { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PMY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY8" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 35, "end_pos": 134, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 265, 267 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 138, "end_pos": 140 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 205, "end_pos": 207 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 271, "end_pos": 273 }, { "start_pos": 317, "end_pos": 319 }, { "start_pos": 367, "end_pos": 369 }, { "start_pos": 39, "end_pos": 41 }, { "start_pos": 43, "end_pos": 45 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PMY9-1", "uniprot_ac": "A0A8M9PMY9", "uniprot_id": "A0A8M9PMY9_DANRE", "mass": { "chemical_mass": 48803.0, "monoisotopic_mass": 48803.0 }, "refseq": { "ac": "XP_005170723", "name": "G-protein coupled receptor 22-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170723" }, "gene_names": [ { "name": "gpr22b", "type": "recommended", "evidence": [ { "id": "A0A8M9PMY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY9" } ] }, { "name": "gpr22b", "type": "synonym", "evidence": [ { "id": "XP_005170723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170723" } ] } ], "protein_names": [ { "name": "G-protein coupled receptor 22", "type": "recommended", "evidence": [ { "id": "A0A8M9PMY9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY9/entry#names_and_taxonomy" } ] }, { "name": "G-protein coupled receptor 22-like", "type": "synonym", "evidence": [ { "id": "XP_005170723", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170723" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005170723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170723" } ] } ], "disease": [ { "disease_id": "DOID:9351", "recommended_name": { "id": "DOID:9351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9351", "name": "diabetes mellitus", "description": "A glucose metabolism disease that is characterized by chronic hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism resulting from defects in insulin secretion, insulin action, or both." }, "synonyms": [ { "id": "DOID:9351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9351", "name": "diabetes", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9351" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PMY9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gpr22b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141212-234", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-234", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00637", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00637", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100150048", "url": "https://www.ncbi.nlm.nih.gov/gene/100150048", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100150048", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100150048", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VGPSDLM", "url": "https://omabrowser.org/oma/group/VGPSDLM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PMY9", "url": "https://www.orthodb.org/?gene=A0A8M9PMY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24241:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24241:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005170723", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005170723", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PMY9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PMY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-141212-234", "url": "https://zfin.org/ZDB-GENE-141212-234", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MHVPPAAEEESTMSNVTVLDITESVSPVMTAAGGPYPYPLSFQVSLTGFLMLEIVLGLSSNLTVLALYCMKSNLVNSVSNIVTMNLHVLDVLVCVCCIPLTIVVLMLSLQGDTVLVCCFHEACVSFASVATAANVLAITLDRYDISVKPANRVLTMGRAVALLGCIWVLSFVSFLVPFIEVGFLGPEPTLANQTAVVHVNEYYTELGLYYHLVAQIPIFCLTAVIMLMTYAKILQALNIRIGTRFHATQKKKKKLRRKKNFSLMSTSEQQLPEITDASQSSGGTRGNAPLGMRTSVSVIIALRRAVKRHRERRERQKRVFRMSLLIISTFLLCWTPITVLNTVILSAGPSDLTVKLRLGFLVMAYGTTVFHPLLYAFTRQKFQKVLKSKMKKRVVSISEADPLPNNAVIRNSWIDPKRNKKVTFDDHEARQKCLSSEDAD", "length": 440, "header": "tr|A0A8M9PMY9-1|A0A8M9PMY9_DANRE Isoform 1 of G-protein coupled receptor 22 OS=Danio rerio OX=7955 GN=gpr22b PE=4 SV=1 CANONICAL=A0A8M9PMY9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PMY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PMY9/entry#A0A8M9PMY9-1", "sequence": { "sequence": "MHVPPAAEEESTMSNVTVLDITESVSPVMTAAGGPYPYPLSFQVSLTGFLMLEIVLGLSSNLTVLALYCMKSNLVNSVSNIVTMNLHVLDVLVCVCCIPLTIVVLMLSLQGDTVLVCCFHEACVSFASVATAANVLAITLDRYDISVKPANRVLTMGRAVALLGCIWVLSFVSFLVPFIEVGFLGPEPTLANQTAVVHVNEYYTELGLYYHLVAQIPIFCLTAVIMLMTYAKILQALNIRIGTRFHATQKKKKKLRRKKNFSLMSTSEQQLPEITDASQSSGGTRGNAPLGMRTSVSVIIALRRAVKRHRERRERQKRVFRMSLLIISTFLLCWTPITVLNTVILSAGPSDLTVKLRLGFLVMAYGTTVFHPLLYAFTRQKFQKVLKSKMKKRVVSISEADPLPNNAVIRNSWIDPKRNKKVTFDDHEARQKCLSSEDAD", "length": 440, "header": "tr|A0A8M9PMY9-1|A0A8M9PMY9_DANRE Isoform 1 of G-protein coupled receptor 22 OS=Danio rerio OX=7955 GN=gpr22b PE=4 SV=1 CANONICAL=A0A8M9PMY9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100150048", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100150048", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R9YJI3-1", "protein_name": "G protein-coupled receptor 22", "gene_name": "gpr22a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESMPSSLTHQRFGLLNKHLTRTGNTREGRMHTPPVLGFQAIMSNVTVLDNIEPLDFEMDLKTPYPVSFQVSLTGFLMLEIVLGLSSNLTVLALYCMKSNLVSSVSNIVTMNLHVLDVLVCVGCIPLTIVVVLLPLEGNNALICCFHEACVSFASVATAANVLAITLDRYDISVRPANRVLTMGRAVALLGSIWALSFFSFLVPFIEEGFFSQAGNERNQTEAEEPSNEYYTELGLYYHLLAQIPIFFFTAVVMLVTYYKILQALNIRIGTRFHSVPKKKPRKKKTISMTSTQPESTDASQSSAGRNAPLGMRTSVSVIIALRRAVKRHRERRERQKRVFRMSLLIISTFLLCWTPITVLNTVILSVGPSNFTVRLRLGFLVMAYGTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSVVEADPMPNNVVIHNSWIDPKRNKKVTFEETEVRQKCLSSEDVE", "length": 460 }, "evidence": [ { "id": "HGNC:4477", "url": "https://alliancegenome.org/gene/HGNC:4477#orthology", "database": "AGR" }, { "id": "RGD:1310848", "url": "https://alliancegenome.org/gene/RGD:1310848#orthology", "database": "AGR" }, { "id": "MGI:1920260", "url": "https://alliancegenome.org/gene/MGI:1920260#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A3U0-1", "protein_name": "G protein-coupled receptor 22", "gene_name": "Gpr22", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCFSPVLEINMQSESNVTVRDDIEDIDTNMYQPLSYPLSFQVSLTGFLMLEIVLGLGSNLTVLVLYCMKSNLISSVSNIITMNLHVLDVIICVGCIPLTIVILLLSLERNTALICCFHEACVSFASVSTAINVFAITLDRYDISVKPANRILTMGRAVMLMTSIWIFSFFSFLIPFIEVNFFSLQSGNAWENKTLLCVSTSEYYTELGMYYHLLVQIPIFFFTVIVMLITYTKILQALNIRIGTRFSTGQKKKARKKKTISLTTHETTDMSQSSGGRNVVFGVRTSVSVIIALRRAVKRHRERRERQKRVFKMSLLIISTFLLCWTPISVLNTTILCLGPSDLLVKLRLCFLVMAYGTTIFHPLLYAFTRQKFQKVLKSKMKKRVVSIVEADPMPNNAVIHNSWIDPKRNKKVTYEDSEIREKCLVPQVVTD", "length": 432 }, "evidence": [ { "id": "HGNC:4477", "url": "https://alliancegenome.org/gene/HGNC:4477#orthology", "database": "AGR" }, { "id": "RGD:1310848", "url": "https://alliancegenome.org/gene/RGD:1310848#orthology", "database": "AGR" }, { "id": "MGI:1920260", "url": "https://alliancegenome.org/gene/MGI:1920260#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141212-234", "url": 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This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity." }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "NIDDM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2D", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM - type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "noninsulin-dependent diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus non-insulin dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type II diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "diabetes mellitus, noninsulin-dependent, type 1", "description": "" }, { "id": "MONDO:0011027", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011027", "name": "NIDDM1", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "NIDDM2", "description": "" }, { "id": "MONDO:0011072", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011072", "name": "diabetes mellitus, noninsulin-dependent, 2", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "diabetes mellitus, noninsulin-dependent, type 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "type 2 diabetes mellitus 3", "description": "" }, { "id": "MONDO:0011363", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011363", "name": "NIDDM3", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, 4", "description": "" }, { "id": "MONDO:0011955", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011955", "name": "diabetes mellitus, noninsulin-dependent, type 4", "description": "" }, { "id": "MIM:125853", "resource": "MIM", "url": "https://www.omim.org/entry/125853", "name": "Type 2 diabetes mellitus", "description": "Type 2 diabetes mellitus" }, { "id": "MIM:601283", "resource": "MIM", "url": "https://www.omim.org/entry/601283", "name": "Type 2 diabetes mellitus 1", "description": "Type 2 diabetes mellitus 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "9352", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9352" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PN98", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN98" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mtnr1ab", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN98", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080107-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080107-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PN98", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PN98", "database": "AlphaFoldDB", "categories": [] }, { "id": "565718", "url": "https://www.ncbi.nlm.nih.gov/gene/565718", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002278", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002278", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565718", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565718", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YTISIEC", "url": "https://omabrowser.org/oma/group/YTISIEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24228:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24228:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021328498", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328498", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PN98", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PN98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080107-4", "url": "https://zfin.org/ZDB-GENE-080107-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKINGSGLMNSSSLSPHDENTLNRPPWVATTLGSFLIFTIVVDILGNLLVIFSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLVSIFHNGWNLGFVHCQISGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSDKNSLCYVLLIWILTVVAIVPNFYVGSLQYDPRVYSCTFAQSASSAYTIAVVFFHFILPIMIVTYCYLRIWILVIQVRRRVKPEFRPKLTPHDIRNFVTMFVVFVLFAVCWAPLNFIGLAVAINPDQVAPLIPEWFFVSSYFMAYFNSCLNAIVYGLLNQNFRREYKKIIISLCTARMFFPESSNDAVERIKSKPSPLMTNNNQVKVDSV", "length": 352, "header": "tr|A0A8M9PN98-1|A0A8M9PN98_DANRE Isoform 1 of Melatonin receptor type 1A-A OS=Danio rerio OX=7955 GN=mtnr1ab PE=3 SV=1 CANONICAL=A0A8M9PN98-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PN98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN98/entry#A0A8M9PN98-1", "sequence": { "sequence": "MKINGSGLMNSSSLSPHDENTLNRPPWVATTLGSFLIFTIVVDILGNLLVIFSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLVSIFHNGWNLGFVHCQISGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSDKNSLCYVLLIWILTVVAIVPNFYVGSLQYDPRVYSCTFAQSASSAYTIAVVFFHFILPIMIVTYCYLRIWILVIQVRRRVKPEFRPKLTPHDIRNFVTMFVVFVLFAVCWAPLNFIGLAVAINPDQVAPLIPEWFFVSSYFMAYFNSCLNAIVYGLLNQNFRREYKKIIISLCTARMFFPESSNDAVERIKSKPSPLMTNNNQVKVDSV", "length": 352, "header": "tr|A0A8M9PN98-1|A0A8M9PN98_DANRE Isoform 1 of Melatonin receptor type 1A-A OS=Danio rerio OX=7955 GN=mtnr1ab PE=3 SV=1 CANONICAL=A0A8M9PN98-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:565718", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565718", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACK0-1", "protein_name": "G protein-coupled receptor 84", "gene_name": "Gpr84", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWNSSDDNFSCYHESVLGYRYFAVIWGMVVAATGTVGNVLTLLALAIRPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGAIFCRIFGLLLFTSNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVGSWVVGVTSFAPLWNVYVLVPVVCTCSFDRVRGRPYTTILMGIFFVVGLSSVGVFYCLIHRQVKRAARALDKYGLQEASMRSHQVSGTHEAVPGHFQELDSGLASRGPSEGISSEPVSAATTQTLEGDSSEAGDQGMRKAAQQISERSLPEVHRKTGGAAGARRATDAPSEFGKVTRMCFAVFLCFVLSYIPFLLLNILDARGRAPRVVHMVAANLTWLNSCINPVLYAAMNRQFRQAYGSILKRGPQSFRRFH", "length": 396 }, "evidence": [ { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O88495-1", "protein_name": "Melatonin-related receptor", "gene_name": "Gpr50", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATVPKSNMGPTKAVPTPFGCIGCKLPKPDYPPALIIFMFCAMVITVVVDLIGNSMVILAVTKNKKLRNSGNIFVASLSVADMLVAIYPYPLMLYAMSVGGWDLSQLQCQMVGLVTGLSVVGSIFNITAIAINRYCYICHSLQYKRIFSLRNTCIYLVVTWVMTVLAVLPNMYIGTIEYDPRTYTCIFNYVNNPAFTVTIVCIHFVLPLIIVGYCYTKIWIKVLAARDPAGQNPDNQFAEVRNFLTMFVIFLLFAVCWCPVNVLTVLVAVIPKEMAGKIPNWLYLAAYCIAYFNSCLNAIIYGILNESFRREYWTIFHAMRHPILFISHLISDIRETWETRALTRARVRARDQVREQERARACVAVEGTPRNVRNVLLPGDASAPHSDRASVRPKPQTRSTSVYRKPASIHHKSISGHPKSASVYPKPASSVHCKPASVHFKPASVHFKGDSVYFKGDTVHYRAASKLVTSHRISAGPSTSHPTSMAGYIKSGTSHPATTTVDYLEPATTSHSVLTAVDLPEVSASHCLEMTSTGHLRADISASVLPSVPFELAATPPDTTAIPIASGDYRKVVLIDDDSDDSDCSDEMAV", "length": 591 }, "evidence": [ { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P48039-1", "protein_name": "Melatonin receptor type 1A", "gene_name": "MTNR1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV", "length": 350 }, "evidence": [ { "id": "HGNC:7463", "url": "https://alliancegenome.org/gene/HGNC:7463#orthology", "database": "AGR" }, { "id": "MGI:102967", "url": "https://alliancegenome.org/gene/MGI:102967#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080107-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080107-4#orthology", "database": "AGR" }, { "id": "RGD:620797", "url": "https://alliancegenome.org/gene/RGD:620797#orthology", "database": "AGR" }, { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49218-1", "protein_name": "Melatonin receptor type 1A", "gene_name": "Mtnr1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "CYICHSLKYDRIYSNKNSLCYVFLIWTLTLIAIMPNLQTGTLQYDPRIYSCTFTQSVSSAYTIALVVFHFVVPMIIVTFCYLRIWILVLQVRRRVKPDSKPKLKPQDFRNFVTMFVVFVLFALCWAPLNFIGLIVASDPATMAPRIPEWLFVASYY", "length": 156 }, "evidence": [ { "id": "HGNC:7463", "url": "https://alliancegenome.org/gene/HGNC:7463#orthology", "database": "AGR" }, { "id": "MGI:102967", "url": "https://alliancegenome.org/gene/MGI:102967#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080107-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080107-4#orthology", "database": "AGR" }, { "id": "RGD:620797", "url": "https://alliancegenome.org/gene/RGD:620797#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P49286-1", "protein_name": "Melatonin receptor type 1B", "gene_name": "MTNR1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL", "length": 362 }, "evidence": [ { "id": "RGD:620798", "url": "https://alliancegenome.org/gene/RGD:620798#orthology", "database": "AGR" }, { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P49287-1", "protein_name": "Melatonin receptor type 1B", "gene_name": "Mtnr1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPDNSSIANCCAASGLAARPSWPGSAEAEPPETPRAPWVAPMLSTVVIVTTAVDFVGNLLVILSVLRNRKLRNAGNLFVVNLALADLVVALYPYPLILVAILHDGWVLGEIHCKASAFVMGLSVIGSVFNITAIAINRYWCICHSATYHRACSQWHAPLYISLIWLLTLVALVPNFFVGSLEYDPRIYSCTFIQTASTQYTMAVVAIHFLLPIAVVSFCYLRIWILVLQARRKAKAERKLRLRPSDLRSFLTMFAVFVVFAICWAPLNCIGLAVAINPEAMALQIPEGLFVTSYFLAYFNSCLNAIVYGLLNQNFRREYKRILSALWSTGRCFHDASKCHLTEDLQGPVPPAAMATIPVQEGAL", "length": 364 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080107-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080107-4#orthology", "database": "AGR" }, { "id": "RGD:620798", "url": "https://alliancegenome.org/gene/RGD:620798#orthology", "database": "AGR" }, { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P51046-1", "protein_name": "Melatonin receptor type 1A-A", "gene_name": "mtnr1aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFMNGSSLNSSALDPSEQALQRPPWVTTTLGCFLIFTIVVDILGNLLVIFSVYRNKKLQNAGNIFVVSLAVADLVVAIYPYPLVLTSIFHRGWNLGYMHCQISGFLMGVSVIGSIFNITGIAINCYCYICHSLKYDKLYSDKNSVCYVLLIWALTVLAIVPNLFVGSLQYDPRVYSCTFEQSASSAYTIAVVFFHFILPIMIVTYCYLRIWVLVIQVRRRVKNDNRPKITPHDVRNFVTMFVVFVLFAVCWAPLNFIGLAVAISPERVVPLIPEWLFVASYFMAYFNSCLNAIVYGVLNQNFRREYKRIVVSVCTARIFFGESSNEAQERLKSKPSPLMTNNNQVKVDSV", "length": 350 }, "evidence": [ { "id": "HGNC:7463", "url": "https://alliancegenome.org/gene/HGNC:7463#orthology", "database": "AGR" }, { "id": "MGI:102967", "url": "https://alliancegenome.org/gene/MGI:102967#orthology", "database": "AGR" }, { "id": "RGD:620798", "url": "https://alliancegenome.org/gene/RGD:620798#orthology", "database": "AGR" }, { "id": "RGD:620797", "url": "https://alliancegenome.org/gene/RGD:620797#orthology", "database": "AGR" }, { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P51047-1", "protein_name": "Melatonin receptor type 1A-like", "gene_name": "mtnr1al", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "CHSLKYDKLFSNKNTVCYVILVWALTVLAIVPNWFVESLQYDPRVFSCTFAQSVSSLYTIMVVVVHFIVPIGIVTYCYLRIWILVIQVPRRVKPDSRPKIKPHDFRNFLTMFVVFVLFAVCWAPLNFIGLAVAIHPRLGQSIPEWLFTASYF", "length": 152 }, "evidence": [ { "id": "HGNC:7463", "url": "https://alliancegenome.org/gene/HGNC:7463#orthology", "database": "AGR" }, { "id": "RGD:620797", "url": "https://alliancegenome.org/gene/RGD:620797#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P51049-1", "protein_name": "Melatonin receptor type 1B-B", "gene_name": "mtnr1bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPENIAFLTNSTDLGHVGRALGSSARPAWAIAVLASVLIFTTVVDVLGNLLVIISVFRNRKLRNAGNVFVVSLAFADLVVAFYPYPLVLYAIFHDGWSLGETQCKISGFLMGLSVIGSVFNITGIAINRYCYICHSFAYGRLYSFRNTLLLVALIWALTVLAILPNFFVGSLSYDPRVYSCTFTQTASSSYTVVVVVVHFLVPIAVVTFCYLRIWVLVIQVRRKVKSEERSRVRPSDLRNFVTMFVVFVLFAICWAPLNLIGLVVAINPEVMAPRVPEWLFVVSYFMAYFNSCLNAIIYGLLNRNFRKEYVRIMTAVWIPRRFVTETSRAATDGMRSKPSPAINNNE", "length": 347 }, "evidence": [ { "id": "RGD:620798", "url": "https://alliancegenome.org/gene/RGD:620798#orthology", "database": "AGR" }, { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q13585-1", "protein_name": "Melatonin-related receptor", "gene_name": "GPR50", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPTLAVPTPYGCIGCKLPQPEYPPALIIFMFCAMVITIVVDLIGNSMVILAVTKNKKLRNSGNIFVVSLSVADMLVAIYPYPLMLHAMSIGGWDLSQLQCQMVGFITGLSVVGSIFNIVAIAINRYCYICHSLQYERIFSVRNTCIYLVITWIMTVLAVLPNMYIGTIEYDPRTYTCIFNYLNNPVFTVTIVCIHFVLPLLIVGFCYVRIWTKVLAARDPAGQNPDNQLAEVRNFLTMFVIFLLFAVCWCPINVLTVLVAVSPKEMAGKIPNWLYLAAYFIAYFNSCLNAVIYGLLNENFRREYWTIFHAMRHPIIFFSGLISDIREMQEARTLARARAHARDQAREQDRAHACPAVEETPMNVRNVPLPGDAAAGHPDRASGHPKPHSRSSSAYRKSASTHHKSVFSHSKAASGHLKPVSGHSKPASGHPKSATVYPKPASVHFKADSVHFKGDSVHFKPDSVHFKPASSNPKPITGHHVSAGSHSKSAFSAATSHPKPTTGHIKPATSHAEPTTADYPKPATTSHPKPTAADNPELSASHCPEIPAIAHPVSDDSDLPESASSPAAGPTKPAASQLESDTIADLPDPTVVTTSTNDYHDVVVIDVEDDPDEMAV", "length": 617 }, "evidence": [ { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61184-1", "protein_name": "Melatonin receptor type 1A", "gene_name": "Mtnr1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGNVSELLNATQQAPGGGEGGRPRPSWLASTLAFILIFTIVVDILGNLLVILSVYRNKKLRNSGNIFVVSLAVADLVVAVYPYPLVLTSILNNGWNLGYLHCQVSAFLMGLSVIGSIFNITGIAMNRYCYICHSLKYDKIYSNKNSLCYVFLIWMLTLIAIMPNLQTGTLQYDPRIYSCTFTQSVSSAYTIAVVVFHFIVPMIIVIFCYLRIWVLVLQVRRRVKPDNKPKLKPQDFRNFVTMFVVFVLFAICWAPLNLIGLIVASDPATMVPRIPEWLFVASYYLAYFNSCLNAIIYGLLNQNFRKEYKKIIVSLCTAKMFFVESSNEEADKIKCKPSPLIPNNNLIKVDSV", "length": 353 }, "evidence": [ { "id": "HGNC:7463", "url": "https://alliancegenome.org/gene/HGNC:7463#orthology", "database": "AGR" }, { "id": "MGI:102967", "url": "https://alliancegenome.org/gene/MGI:102967#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080107-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080107-4#orthology", "database": "AGR" }, { "id": "RGD:620797", "url": "https://alliancegenome.org/gene/RGD:620797#orthology", "database": "AGR" }, { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CIM5-1", "protein_name": "G protein-coupled receptor 84", "gene_name": "Gpr84", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWNSSDANFSCYHESVLGYRYFAVIWGVAVAVTGTVGNVLTLLALAIRPKLRTRFNLLIANLTLADLLYCTLLQPFSVDTYLHLHWRTGAVFCRIFGLLLFTSNSVSILTLCLIALGRYLLIAHPKLFPQVFSAKGIVLALVGSWVVGVTSFAPLWNVFVLVPVVCTCSFDRMRGRPYTTILMGIYFVLGLSSVGVFYCLIHRQVKRAARALDQYGLHQASIRSHQVAGTQEAMPGHFQELDSGVASRGPSEGISSEPVSAATTQTLEGDSSEAGGQGIRKAAQQIAERSLPEVHRKPRETAGARRATDAPSEFGKVTRMCFAVFLCFALSYIPFLLLNILDARGRAPRVVHMVAANLTWLNSCINPVLYAAMNRQFRHAYGSILKRGPQSFRRFH", "length": 396 }, "evidence": [ { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CIQ6-1", "protein_name": "Melatonin receptor type 1B", "gene_name": "Mtnr1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPENSSIPNCCEASGLAARPSWSGSAGARPPVTARAPWVAPMLSTVVVVTTAVDFVGNLLVILSVLRNRKLRNAGNLFVVSLALADLVIALYPYPLILVAIIRDGWVLGEAHCKASAFVMGLSVIGSVFNITAIAINRYCCICHSTTYHRVCSHWYTPIYISLVWLLTLVALVPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVAIHFLLPMAVVSFCYLRIWVLVLQARRKAKATRKLRLRPSDLRSFLTMFAVFVVFAICWAPLNCIGLAVAINPEAMALQVPEGLFVTSYFLAYFNSCLNAIVYGLLNQNFRREYKRILLAIWNTRRCIQHASKHCLTEERQGPTPPAARATVPVKEGAL", "length": 364 }, "evidence": [ { "id": "RGD:620798", "url": "https://alliancegenome.org/gene/RGD:620798#orthology", "database": "AGR" }, { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q90456-1", "protein_name": "Melatonin receptor type 1B-A", "gene_name": "mtnr1ba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPENVSLIRNRTEVGQGRAWGSGAGARPAWVVMVLAGVLIFTSVVDVLGNVLVIISVLRNRKLRNAGNAFVVSLAFADLLVVCYPYPLVLHAMLHAGWLPGEMECKVSGFLMGASVIGSIFNITAIAINRYCFICQANTYEKIYGRAGTLVLLTLVWVLTAIAILPNLSLGSLTYDPRVYSCTFSQTTSAGYTIAVVTVHFLLPIAVVTFCYLRIWVLVLRVRRRVTTDVRPRLRPSELRHFLTMFVVFVLFAVCWAPLNLIGLAVAVDPPRVGPLVPDWLFVMSYF", "length": 287 }, "evidence": [ { "id": "RGD:620798", "url": "https://alliancegenome.org/gene/RGD:620798#orthology", "database": "AGR" }, { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9NDM2-1", "protein_name": "Protein trapped in endoderm-1", "gene_name": "Tre1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDQDMGMATGYFQDADMQMDEPAAATQSIYPHSATLFAAISACVFVTIGVLGNLITLLALLKSPTIREHATTAFVISLSISDLLFCSFSLPLTAVRFFQESWTFGTTLCKIFPVIFYGNVAVSLLSMVGITLNRYILIACHSRYSQIYKPKFITLQLLFVWAVSFLLLLPPILGIWGEMGLDEATFSCTILKKEGRSIKKTLFVIGFLLPCLVIIVSYSCIYITVLHQKKKIRNHDNFQIAAAKGSSSSGGGSYMTTTCTRKAREDNRLTVMMVTIFLCFLVCFLPLMLANVVDDERNTSYPWLHIIASVMAWASSVINPIIYAASNRNYRVAYYKIFALLKFWGEPLSPMPSRNYHQSKNSKELSGVIRSTPLFHAVQKNSINQMCQTYSV", "length": 392 }, "evidence": [ { "id": "HGNC:7463", "url": "https://alliancegenome.org/gene/HGNC:7463#orthology", "database": "AGR" }, { "id": "MGI:102967", "url": "https://alliancegenome.org/gene/MGI:102967#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080107-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080107-4#orthology", "database": "AGR" }, { "id": "RGD:620798", "url": "https://alliancegenome.org/gene/RGD:620798#orthology", "database": "AGR" }, { "id": "FB:FBgn0046687", "url": "https://alliancegenome.org/gene/FB:FBgn0046687#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W533-1", "protein_name": "G-protein coupled receptors family 1 profile domain-containing protein", "gene_name": "EG:22E5.10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFPPKSGPTPHPISIALPLSDPYATDHMADQDAVLPVPLSDSLDLDVDVDLNLNMNLNLNVDDRRQVLFEGYSDELLTIAWVACIVFIIVGVPGNLLTIVALSRGRQTRNSTAIFIINLSCSDLLFGCFNLPLAASTFKERAWTHSDLLCRLFPMLRYGLLAVSLLSVSLITINRYIIIAHPRQYPRIYQRRYLALMVAGTWITTFSIMIPTWRGVWGIFGLDVSIGSCSIMHDRYGRSPKEFLFIAAFMVPCICIVICYARIFLLVRKAAIRAGTAGKTNVSDVTPSSAPQHQIQAMATPKKPEKVTTSSGEANEPIAGRPFVVEENLAYIDDNASTDSLPISYSIRRRDQDQQPPPVDANVVLKEREKERDRDQEKVSLGRSQTQLEMGKTHGKNPITTSLRTTSFTRFSPRKSHYASMGNTSNASSIYPGRMSAKDRRLLKMILVIFVWFVICYLPITVAKIWKSATEVHWFNIAGYLLIYLTTCINPLIYVLMSSEYRRAYWNLLRCHGSPDTQKQRNQANAKRKHLESNRQVKATT", "length": 541 }, "evidence": [ { "id": "HGNC:7463", "url": "https://alliancegenome.org/gene/HGNC:7463#orthology", "database": "AGR" }, { "id": "MGI:102967", "url": "https://alliancegenome.org/gene/MGI:102967#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PN98", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN98" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rhythmic process", "id": "GO:0048511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048511", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PN98", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN98" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "melatonin receptor activity", "id": "GO:0008502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008502", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PN98", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN98" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PN98", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PN98" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 297, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 119, "end_pos": 121 }, { "start_pos": 4, "end_pos": 6 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PNA6-1", "uniprot_ac": "A0A8M9PNA6", "uniprot_id": "A0A8M9PNA6_DANRE", "mass": { "chemical_mass": 49400.0, "monoisotopic_mass": 49400.0 }, "refseq": { "ac": "XP_073799245", "name": "uncharacterized protein si:dkey-81e3.2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073799245" }, "gene_names": [ { "name": "si:dkey-81e3.2", "type": "recommended", "evidence": [ { "id": "A0A8M9PNA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNA6" } ] }, { "name": "si:dkey-81e3.2", "type": "synonym", "evidence": [ { "id": "XP_073799245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073799245" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkey-81e3.2", "type": "synonym", "evidence": [ { "id": "A0A8M9PNA6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNA6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkey-81e3.2", "type": "synonym", "evidence": [ { "id": "XP_073799245", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073799245" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073799245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073799245" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNA6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNA6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-81e3.2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNA6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131119-24", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131119-24", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PNA6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PNA6", "database": "AlphaFoldDB", "categories": [] }, { "id": "793178", "url": "https://www.ncbi.nlm.nih.gov/gene/793178", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:793178", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793178", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_073799245", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073799245", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PNA6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNA6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PNA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNA6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131119-24", "url": "https://zfin.org/ZDB-GENE-131119-24", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MELTPAIPFIGDVLNIPDLKLTWLNYGHLVDDEDMPRIMQKWLGLIPAYALHLRVVLAQASESGLTSLNVITWAINEHPHFPWVLVRRMYPEQWDNAQRAIRLVENNPYYGYRRDLTDVRSTQFRHLAALCGRLLIALGDRLLERYQGFVDDKLRVHEWRRMIDAYVNAHGREGANIERPMSEEEIDHHADMMQSVSQYPANIEVLARIDGHPDRPDIGLHGGGPQFRGGPRHRVRRDDDDNVGGGGKAGAYNGEEMYGEDHFRHPINQEYAECGAQERPAIETEERPDQACRVAADQPPADASVAPGASWEVNVNREEAGLKPIVAPHETVTSPPEQSVNEIEDNLFVPPPFSPALSSVKLRLITQTPRTPRLALHYTQVANLGPGCNPGQQLQLGGPPRFSTPTQLQQHQQSALQSSYRAPGSSTTRGQRHSSSAFPPQ", "length": 441, "header": "tr|A0A8M9PNA6-1|A0A8M9PNA6_DANRE Isoform 1 of Uncharacterized protein si:dkey-81e3.2 OS=Danio rerio OX=7955 GN=si:dkey-81e3.2 PE=4 SV=2 CANONICAL=A0A8M9PNA6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PNA6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNA6/entry#A0A8M9PNA6-1", "sequence": { "sequence": 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This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073799373", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073799373" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNB9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNB9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "syt18b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNB9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090602-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090602-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PNB9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PNB9", "database": "AlphaFoldDB", "categories": [] }, { "id": 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cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322715" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PND6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "usf2l", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6", "locus": {} } ], "crossref": [ { "id": "A0A8M9PND6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PND6", "database": "AlphaFoldDB", "categories": [] }, { "id": "101886727", "url": "https://www.ncbi.nlm.nih.gov/gene/101886727", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051732", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051732", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101886727", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886727", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PND6", "url": "https://www.orthodb.org/?gene=A0A8M9PND6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46117:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46117:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00010", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00010", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322715", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322715", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PND6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PND6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T5L3", "url": "https://www.uniprot.org/uniprotkb/A0AB32T5L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T5L3-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T5L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLL5", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLL5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLL5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLL5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWFPQPDSLDPSSNTGSPAGDESREEARCGYFPASSVSEGSASIVSLQTAADHTFPQTAGQFYVMMTPSDVLHSASQRTLAPRTHTYTVNEHSTYQHEGLNWKTDSPRTPRDERRRAQHNEVERRRRDKINNWIETLSKIIPDCSFDGTKTGASKGGILSKACDYIVELKQQKQRLQESLRAVERLKMDNELLTKQVEELKSENALLGALLEHHGIGTITDTSAP", "length": 225, "header": "tr|A0A8M9PND6-1|A0A8M9PND6_DANRE Isoform 1 of Upstream stimulatory factor 2 isoform X1 OS=Danio rerio OX=7955 GN=usf2l PE=4 SV=1 CANONICAL=A0A8M9PND6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PND6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6/entry#A0A8M9PND6-1", "sequence": { "sequence": "MWFPQPDSLDPSSNTGSPAGDESREEARCGYFPASSVSEGSASIVSLQTAADHTFPQTAGQFYVMMTPSDVLHSASQRTLAPRTHTYTVNEHSTYQHEGLNWKTDSPRTPRDERRRAQHNEVERRRRDKINNWIETLSKIIPDCSFDGTKTGASKGGILSKACDYIVELKQQKQRLQESLRAVERLKMDNELLTKQVEELKSENALLGALLEHHGIGTITDTSAP", "length": 225, "header": "tr|A0A8M9PND6-1|A0A8M9PND6_DANRE Isoform 1 of Upstream stimulatory factor 2 isoform X1 OS=Danio rerio OX=7955 GN=usf2l PE=4 SV=1 CANONICAL=A0A8M9PND6-1" }, "locus": {} }, { "isoform_ac": "A0AB32T5L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6/entry#A0AB32T5L3-1", "sequence": { "sequence": "MWIFPSILCERGIGQHRVLADSSRSHIPTNSRNEHSTYQHEGLNWKTDSPRTPRDERRRAQHNEVERRRRDKINNWIETLSKIIPDCSFDGTKTGASKGGILSKACDYIVELKQQKQRLQESLRAVERLKMDNELLTKQVEELKSENALLGALLEHHGIGTITDTSAP", "length": 168, "header": "tr|A0AB32T5L3-1|A0A8M9PND6_DANRE Computationally mapped isoform of Upstream stimulatory factor 2 isoform X1 OS=Danio rerio OX=7955 GN=usf2l PE=4 SV=1 CANONICAL=A0A8M9PND6-1" }, "locus": {} }, { "isoform_ac": "A0AC58HLL5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6/entry#A0AC58HLL5-1", "sequence": { "sequence": "MWFPQPDSLDPSSNTGSPAGDESREEARCGYFPASSVSEGSASIVSLQTAADHTFPQTAGQFYVMMTPSDVLHSASQRTLAPRTHTYTVKTDSPRTPRDERRRAQHNEVERRRRDKINNWIETLSKIIPDCSFDGTKTGASKGGILSKACDYIVELKQQKQRLQESLRAVERLKMDNELLTKQVEELKSENALLGALLEHHGIGTITDTSAP", "length": 212, "header": "tr|A0AC58HLL5-1|A0AC58HLL5_DANRE Computationally mapped isoform of Upstream stimulatory factor 2 isoform X2 OS=Danio rerio OX=7955 GN=usf2l PE=4 SV=1 CANONICAL=A0A8M9PND6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101886727", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886727", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PND6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PND6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PND6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6" } ], "pmid": "" }, { "name": "positive regulation of transcription by RNA polymerase II", "id": "GO:0045944", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045944", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PND6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "protein dimerization activity", "id": "GO:0046983", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046983", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PND6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PND6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PND6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PND6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PND6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND6" }, { "id": "PS50888", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50888" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BHLH", "eco_id": "ECO_0000259", "start_pos": 114, "end_pos": 169, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PND8-1", "uniprot_ac": "A0A8M9PND8", "uniprot_id": "A0A8M9PND8_DANRE", "mass": { "chemical_mass": 46359.0, "monoisotopic_mass": 46359.0 }, "refseq": { "ac": "XP_021326394", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326394" }, "gene_names": [ { "name": "LOC101884923", "type": "recommended", "evidence": [ { "id": "A0A8M9PND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND8" } ] }, { "name": "LOC101884923", "type": "synonym", "evidence": [ { "id": "XP_021326394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326394" } ] } ], "protein_names": [ { "name": "protein-tyrosine-phosphatase", "type": "recommended", "evidence": [ { "id": "A0A8M9PND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND8/entry#names_and_taxonomy" } ] }, { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "A0A8M9PND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021326394", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326394" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326394" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PND8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101884923", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND8", "locus": {} } ], "crossref": [ { "id": "A0A8M9PND8", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PND8", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd14498", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14498", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101884923", "url": "https://www.ncbi.nlm.nih.gov/gene/101884923", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101884923", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884923", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PND8", "url": "https://www.orthodb.org/?gene=A0A8M9PND8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10159", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10159", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10159:SF519", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10159:SF519", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021326394", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326394", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PND8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PND8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYT5", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYT5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNVCNKTRGWKMETLEKWSRDIMAPQQLDKKEHPKQNGMIAKNLLNSLKTRNRLHLQPISRSACATGSCPDLMSRNEQPDSRPLAMALTPQLPPRTHRPLCLSVSSDSNGRFKALETQEWKNNLKAQMEQAHSAGAASSTGSLERASLFCASGSTTTSSSGLSSPVEHLTKSKSSSRFSLFSPPWNSSSESDSNPPSRSGSKKMRNYSRRAVPGSAKTGPETPEPKQSVPEHFQYSEPVISKVTDYIYVGNLNAAYNGRTLCRNNIDSVIDMSSLPGETCLRVIPCTCSRGVKHSWSRLKVDMSDLPDTVQEGLALKHRCFEDINECIDASTEKKKRVLVHCRDGFSLAPTCIIQYLMVKQNMRLIAAYELLRAKHPVNIRESHQNVLVSLERALRPGGNTDPECFKQAISRKVAWT", "length": 417, "header": "tr|A0A8M9PND8-1|A0A8M9PND8_DANRE Isoform 1 of protein-tyrosine-phosphatase OS=Danio rerio OX=7955 GN=LOC101884923 PE=3 SV=1 CANONICAL=A0A8M9PND8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PND8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND8/entry#A0A8M9PND8-1", "sequence": { "sequence": "MNVCNKTRGWKMETLEKWSRDIMAPQQLDKKEHPKQNGMIAKNLLNSLKTRNRLHLQPISRSACATGSCPDLMSRNEQPDSRPLAMALTPQLPPRTHRPLCLSVSSDSNGRFKALETQEWKNNLKAQMEQAHSAGAASSTGSLERASLFCASGSTTTSSSGLSSPVEHLTKSKSSSRFSLFSPPWNSSSESDSNPPSRSGSKKMRNYSRRAVPGSAKTGPETPEPKQSVPEHFQYSEPVISKVTDYIYVGNLNAAYNGRTLCRNNIDSVIDMSSLPGETCLRVIPCTCSRGVKHSWSRLKVDMSDLPDTVQEGLALKHRCFEDINECIDASTEKKKRVLVHCRDGFSLAPTCIIQYLMVKQNMRLIAAYELLRAKHPVNIRESHQNVLVSLERALRPGGNTDPECFKQAISRKVAWT", "length": 417, "header": "tr|A0A8M9PND8-1|A0A8M9PND8_DANRE Isoform 1 of protein-tyrosine-phosphatase OS=Danio rerio OX=7955 GN=LOC101884923 PE=3 SV=1 CANONICAL=A0A8M9PND8-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND8/entry#A0AC58IYT5-1", "sequence": { "sequence": "MFYMCCMGWKMETLEKWSRDIMAPQQLDKKEHPKQNGMIAKNLLNSLKTRNRLHLQPISRSACATGSCPDLMSRNEQPDSRPLAMALTPQLPPRTHRPLCLSVSSDSNGRFKALETQEWKNNLKAQMEQAHSAGAASSTGSLERASLFCASGSTTTSSSGLSSPVEHLTKSKSSSRFSLFSPPWNSSSESDSNPPSRSGSKKMRNYSRRAVPGSAKTGPETPEPKQSVPEHFQYSEPVISKVTDYIYVGNLNAAYNGRTLCRNNIDSVIDMSSLPGETCLRVIPCTCSRGVKHSWSRLKVDMSDLPDTVQEGLALKHRCFEDINECIDASTEKKKRVLVHCRDGFSLAPTCIIQYLMVKQNMRLIAAYELLRAKHPVNIRESHQNVLVSLERALRPGGNTDPECFKQAISRKVAWT", "length": 416, "header": "tr|A0AC58IYT5-1|A0AC58IYT5_DANRE Computationally mapped isoform of protein-tyrosine-phosphatase OS=Danio rerio OX=7955 GN=LOC101884923 PE=3 SV=1 CANONICAL=A0A8M9PND8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "dre:101884923", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884923", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PND8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PND8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PND8" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 318, "end_pos": 387, "start_aa": "His", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.48", "ec_name": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48" }, { "id": "3.1.3.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.48" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 206, "end_pos": 208 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PNE5-1", "uniprot_ac": "A0A8M9PNE5", "uniprot_id": "A0A8M9PNE5_DANRE", "mass": { "chemical_mass": 30512.0, "monoisotopic_mass": 30512.0 }, "refseq": { "ac": "XP_021333012", "name": "coiled-coil domain-containing protein 122", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333012" }, "gene_names": [ { "name": "ccdc122", "type": "recommended", "evidence": [ { "id": "A0A8M9PNE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNE5" } ] }, { "name": "ccdc122", "type": "synonym", "evidence": [ { "id": "XP_021333012", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333012" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 122", "type": "synonym", "evidence": [ { "id": "A0A8M9PNE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNE5/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 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This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021333012.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021333012", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333012" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNE5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNE5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ccdc122", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNE5", "locus": {} } ], "crossref": [ { "id": "A0A8M9PNE5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PNE5", "database": "AlphaFoldDB", "categories": [] }, { "id": "103910356", "url": "https://www.ncbi.nlm.nih.gov/gene/103910356", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:103910356", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910356", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PNE5", "url": "https://www.orthodb.org/?gene=A0A8M9PNE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF28420", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28420", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021333012", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333012", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PNE5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PNE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNE5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MDSLSQQDFPLKDALQELLQQGEARAQQISNAQRALHTLQDSLEVMERSRESVCSQVRLKQKMLTALHCDAETLQCSIMQLQVQTQSAAMQNLQLRAQMQDQQEQRRSQLQEFSSYRSRLQAFRCAVSPQQSPAHVCEELQMKMQEIRRLTHTLEEMKRQHADSRSGLHTQEDIEFLKTRINEARQTMKDSRAHLDNEKHTHTQLRREIEIQRRRCEAIQKRLRCQLKKTQSSQRRLRSDVTHMQKQLEELRRLEER", "length": 257, "header": "tr|A0A8M9PNE5-1|A0A8M9PNE5_DANRE Isoform 1 of Coiled-coil domain-containing protein 122 OS=Danio rerio OX=7955 GN=ccdc122 PE=4 SV=3 CANONICAL=A0A8M9PNE5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PNE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNE5/entry#A0A8M9PNE5-1", "sequence": { "sequence": "MDSLSQQDFPLKDALQELLQQGEARAQQISNAQRALHTLQDSLEVMERSRESVCSQVRLKQKMLTALHCDAETLQCSIMQLQVQTQSAAMQNLQLRAQMQDQQEQRRSQLQEFSSYRSRLQAFRCAVSPQQSPAHVCEELQMKMQEIRRLTHTLEEMKRQHADSRSGLHTQEDIEFLKTRINEARQTMKDSRAHLDNEKHTHTQLRREIEIQRRRCEAIQKRLRCQLKKTQSSQRRLRSDVTHMQKQLEELRRLEER", "length": 257, "header": "tr|A0A8M9PNE5-1|A0A8M9PNE5_DANRE Isoform 1 of Coiled-coil domain-containing protein 122 OS=Danio rerio OX=7955 GN=ccdc122 PE=4 SV=3 CANONICAL=A0A8M9PNE5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:103910356", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:103910356", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PNF1-1", "uniprot_ac": "A0A8M9PNF1", "uniprot_id": "A0A8M9PNF1_DANRE", "mass": { "chemical_mass": 20598.0, "monoisotopic_mass": 20598.0 }, "refseq": { "ac": "XP_021322730", "name": "pituitary tumor-transforming gene 1 protein-interacting protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322730" }, "gene_names": [ { "name": "pttg1ip2", "type": "recommended", "evidence": [ { "id": "A0A8M9PNF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNF1" } ] }, { "name": "LOC101886260", "type": "synonym", "evidence": [ { "id": "XP_021322730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322730" }, { "id": "A0A8M9PNF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNF1" } ] } ], "protein_names": [ { "name": "Pituitary tumor-transforming gene 1 protein-interacting protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PNF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNF1/entry#names_and_taxonomy" } ] }, { "name": "pituitary tumor-transforming gene 1 protein-interacting protein", "type": "synonym", "evidence": [ { "id": "XP_021322730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322730" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322730.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322730" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNF1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNF1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "pttg1ip2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNF1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-9644", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-9644", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PNF1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PNF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR052304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101886260", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886260", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PNF1", "url": "https://www.orthodb.org/?gene=A0A8M9PNF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15191", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15191", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15191:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15191:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27838", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27838", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322730", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322730", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PNF1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PNF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-9644", "url": "https://zfin.org/ZDB-GENE-030131-9644", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGKFLVFWSTFLLMCVAFSFSESDSTTTQQPTTAPPVRKPCNTLTSCETCLANVSCLWCLTNSSCSDYPVSYIIPPSSVCKLSQARWGVCWVNFEALIIAMAVVLGVLLLAVTVCCCCCCCKRRSSSSFDRDDEQFARRREEIRQRADERRVERKTKHDEIRKKYGLIPDSDHPYSKFENE", "length": 181, "header": "tr|A0A8M9PNF1-1|A0A8M9PNF1_DANRE Isoform 1 of Pituitary tumor-transforming gene 1 protein-interacting protein OS=Danio rerio OX=7955 GN=pttg1ip2 PE=4 SV=2 CANONICAL=A0A8M9PNF1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PNF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNF1/entry#A0A8M9PNF1-1", "sequence": { "sequence": "MGKFLVFWSTFLLMCVAFSFSESDSTTTQQPTTAPPVRKPCNTLTSCETCLANVSCLWCLTNSSCSDYPVSYIIPPSSVCKLSQARWGVCWVNFEALIIAMAVVLGVLLLAVTVCCCCCCCKRRSSSSFDRDDEQFARRREEIRQRADERRVERKTKHDEIRKKYGLIPDSDHPYSKFENE", "length": 181, "header": "tr|A0A8M9PNF1-1|A0A8M9PNF1_DANRE Isoform 1 of Pituitary tumor-transforming gene 1 protein-interacting protein OS=Danio rerio OX=7955 GN=pttg1ip2 PE=4 SV=2 CANONICAL=A0A8M9PNF1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101886260", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886260", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNF1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNF1" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNF1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNF1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein import into nucleus", "id": "GO:0006606", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006606", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNF1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 62, "end_pos": 64, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 53, "end_pos": 55 }, { "start_pos": 62, "end_pos": 64 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PNH6-1", "uniprot_ac": "A0A8M9PNH6", "uniprot_id": "A0A8M9PNH6_DANRE", "mass": { "chemical_mass": 63638.0, "monoisotopic_mass": 63638.0 }, "refseq": { "ac": "XP_021323796", "name": "glucocorticoid modulatory element-binding protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323796" }, "gene_names": [ { "name": "gmeb1", "type": "recommended", "evidence": [ { "id": "A0A8M9PNH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6" } ] }, { "name": "gmeb1", "type": "synonym", "evidence": [ { "id": "XP_021323796", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323796" } ] }, { "name": "si:ch211-245h7.5", "type": "synonym", "evidence": [ { "id": "XP_021323796", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323796" }, { "id": "A0A8M9PNH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6" } ] } ], "protein_names": [ { "name": "Glucocorticoid modulatory element-binding protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PNH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6/entry#names_and_taxonomy" } ] }, { "name": "glucocorticoid modulatory element-binding protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323796", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323796" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323796", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323796" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gmeb1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-35", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-35", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PNH6", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PNH6", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000062060", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000062060", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "567701", "url": "https://www.ncbi.nlm.nih.gov/gene/567701", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010919", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010919", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059099", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059099", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567701", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567701", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVTXLER", "url": "https://omabrowser.org/oma/group/QVTXLER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PNH6", "url": "https://www.orthodb.org/?gene=A0A8M9PNH6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1QN94", "url": "https://www.orthodb.org/?gene=F1QN94", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10417", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10417", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10417:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10417:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01342", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01342", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25892", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25892", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323796", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323796", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PNH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QN94", "url": "https://www.uniprot.org/uniprotkb/F1QN94", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QN94-1", "url": "https://www.uniprot.org/uniprotkb/F1QN94-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-35", "url": "https://zfin.org/ZDB-GENE-060503-35", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAEAEVTVTVEDMVVMKSSEEEDVEPDNQSKTQMILQLQPMTAGLGDESNETDAAVVAVEDEVSAEGEDLELGYPITCGESKAILLFKKFVCPGINVRCVKYEDQLISPKQFVHMSGKATLKDWKRAIRMGGVMLRKMMDSGQLDFYQHSTLCTNTCRSTKFDLLINNTRFPPDGSGLNTPITAAEYVFPAGHVTVGNGGQAATVEEKKEDVIGAVEWSPDTSDKRDTSEISEETLSFWRGIAEVGLMGEVVSNIRSELLGLLRGVQLRTDQSSLQDAEIAVLSNLAQVFNLLDSIKQILNVRRQMTDPEQTQVLRTLTTLEQQLEEQKMQQSLSWSSQSQALSSLVLPSTPPAKRAPKRPRLQRPASTTVLSTSIAQPLTLQPQQFTVFSPITLSSIGQSFAVANLSPPSNTVTLHALPAGSQLFTRIAGGSDGKTEAITLHPASGLTLLGATAMQDPSQLGTVVSPVELVQLTQKATNAGVTQDGQVVTGTVVMQEGVVRVVQEDENQENATLIEIDPATADQSVSVMELQLEGDEAAGAATVVEGGEEVVQGEMEETGEIQLDANGQFHNLPIVVVEEDEQDVGKAK", "length": 590, "header": "tr|A0A8M9PNH6-1|A0A8M9PNH6_DANRE Isoform 1 of Glucocorticoid modulatory element-binding protein 1 isoform X1 OS=Danio rerio OX=7955 GN=gmeb1 PE=4 SV=1 CANONICAL=A0A8M9PNH6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PNH6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6/entry#A0A8M9PNH6-1", "sequence": { "sequence": "MAEAEVTVTVEDMVVMKSSEEEDVEPDNQSKTQMILQLQPMTAGLGDESNETDAAVVAVEDEVSAEGEDLELGYPITCGESKAILLFKKFVCPGINVRCVKYEDQLISPKQFVHMSGKATLKDWKRAIRMGGVMLRKMMDSGQLDFYQHSTLCTNTCRSTKFDLLINNTRFPPDGSGLNTPITAAEYVFPAGHVTVGNGGQAATVEEKKEDVIGAVEWSPDTSDKRDTSEISEETLSFWRGIAEVGLMGEVVSNIRSELLGLLRGVQLRTDQSSLQDAEIAVLSNLAQVFNLLDSIKQILNVRRQMTDPEQTQVLRTLTTLEQQLEEQKMQQSLSWSSQSQALSSLVLPSTPPAKRAPKRPRLQRPASTTVLSTSIAQPLTLQPQQFTVFSPITLSSIGQSFAVANLSPPSNTVTLHALPAGSQLFTRIAGGSDGKTEAITLHPASGLTLLGATAMQDPSQLGTVVSPVELVQLTQKATNAGVTQDGQVVTGTVVMQEGVVRVVQEDENQENATLIEIDPATADQSVSVMELQLEGDEAAGAATVVEGGEEVVQGEMEETGEIQLDANGQFHNLPIVVVEEDEQDVGKAK", "length": 590, "header": "tr|A0A8M9PNH6-1|A0A8M9PNH6_DANRE Isoform 1 of Glucocorticoid modulatory element-binding protein 1 isoform X1 OS=Danio rerio OX=7955 GN=gmeb1 PE=4 SV=1 CANONICAL=A0A8M9PNH6-1" }, "locus": {} }, { "isoform_ac": "F1QN94-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6/entry#F1QN94-1", "sequence": { "sequence": "MAEAEVTVTVEDMVVMKSSEEEDVEPDNQSKTQMILQLQPMTAGLGDESNETDAAVVAVEDEVSAEGEDLELGYPITCGESKAILLFKKFVCPGINVRCVKYEDQLISPKQFVHMSGKATLKDWKRAIRMGGVMLRKMMDSGQLDFYQHSTLCTNTCRSTKFDLLINNTRFPPDGSGLNTPITAAGHVTVGNGGQAATVEEKKEDVIGAVEWSPDTSDKRDTSEISEETLSFWRGIAEVGLMGEVVSNIRSELLGLLRGVQLRTDQSSLQDAEIAVLSNLAQVFNLLDSIKQILNVRRQMTDPEQTQVLRTLTTLEQQLEEQKMQQSLSWSSQSQALSSLVLPSTPPAKRAPKRPRLQRPASTTVLSTSIAQPLTLQPQQFTVFSPITLSSIGQSFAVANLSPPSNTVTLHALPAGSQLFTRIAGGSDGKTEAITLHPASGLTLLGATAMQDPSQLGTVVSPVELVQLTQKATNAGVTQDGQVVTGTVVMQEGVVRVVQEDENQENATLIEIDPATADQSVSVMELQLEGDEAAGAATVVEGGEEVVQGEMEETGEIQLDANGQFHNLPIVVVEEDEQDVGKAK", "length": 584, "header": "tr|F1QN94-1|F1QN94_DANRE Computationally mapped isoform of Glucocorticoid modulatory element-binding protein 1 OS=Danio rerio OX=7955 GN=gmeb1 PE=4 SV=1 CANONICAL=A0A8M9PNH6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 195, "start_aa": "Thr", "end_pos": 195, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr195", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches.", "journal": "J. Comp. Neurol.", "date": "2015", "authors": "Diotel Nicolas, Rodriguez Viales Rebecca, Armant Olivier, M\u00e4rz Martin, Ferg Marco, Rastegar Sepand, Str\u00e4hle Uwe", "evidence": [ { "database": "UniProtKB", "id": "F1QN94", "url": "https://www.uniprot.org/uniprotkb/F1QN94" } ], "reference": [ { "type": "PubMed", "id": "25556858", "url": "https://glygen.org/publication/PubMed/25556858" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "F1QN94", "url": "https://www.uniprot.org/uniprotkb/F1QN94" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "F1QN94", "url": "https://www.uniprot.org/uniprotkb/F1QN94" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "FOXO genes in channel catfish and their response after bacterial infection.", "journal": "Dev. Comp. Immunol.", "date": "2019", "authors": "Gao Lei, Yuan Zihao, Zhou Tao, Yang Yujia, Gao Dongya, Dunham Rex, Liu Zhanjiang", "evidence": [ { "database": "UniProtKB", "id": "F1QN94", "url": "https://www.uniprot.org/uniprotkb/F1QN94" } ], "reference": [ { "type": "PubMed", "id": "30905685", "url": "https://glygen.org/publication/PubMed/30905685" } ] } ], "pathway": [ { "id": "dre:567701", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567701", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9JL60-1", "protein_name": "Glucocorticoid modulatory element-binding protein 1", "gene_name": "Gmeb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYEAGSENSAAVVAVETHSIHKIEEGIDASSIEGNEDMEIAYPITCGESKAVLLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGNITQIAISEESMEEAGLEWNSALTAAVTMATEEGIKKESEEISEDTLMFWKGIADVGLMEEVVCNIQKEMEELLRGVQQRLIQAPFQVTDAAVLNNVANTFGLMDAVKRVLDNRRKQVEQGEEQFLYTLADLERQLEEQKKQAQDPRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPVQQPQFTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSNSPDTVTIHPSSSLALLSSTSMQDGSSLGNMATMVSPMELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDSEADDTEGKAVILETGLRTEEKVVAEMEEHQHQVHNVEIVVLED", "length": 562 }, "evidence": [ { "id": "HGNC:4370", "url": "https://alliancegenome.org/gene/HGNC:4370#orthology", "database": "AGR" }, { "id": "RGD:1563208", "url": "https://alliancegenome.org/gene/RGD:1563208#orthology", "database": "AGR" }, { "id": "MGI:2135604", "url": "https://alliancegenome.org/gene/MGI:2135604#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-35", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-35#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QUZ8-1", "protein_name": "Glucocorticoid modulatory element-binding protein 1", "gene_name": "Gmeb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGIYEAGSENSAAVVAVETHTIHKIEEGIDASSIEANEDMEIAYPITCGESKAVLLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGNITQIAISEESMEEAGLEWNSALTAAVTMATEEGIKKESEEISEDTLMFWKGIADVGLMEEVVCNIQKEIEELLRGVQQRLIHAPFQVTDAAVLNNVANTFGLMDTVKRVLDNRRKQVEHGEEQFLYTLADLERQLEEQKKQAQDPRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPVQQPQFTVISPITITPVGQSFSMGNIPVATLSQGTSPVTVHTLPSGPQLFRYATVVSSAKSNSPDTVTIHPSSSLALLSSTSMQDGSTLGNMATMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEADDPEGKAVILETELRTEEKVVANMEERQHQVHNVEIVVLED", "length": 562 }, "evidence": [ { "id": "HGNC:4370", "url": "https://alliancegenome.org/gene/HGNC:4370#orthology", "database": "AGR" }, { "id": "RGD:1563208", "url": "https://alliancegenome.org/gene/RGD:1563208#orthology", "database": "AGR" }, { "id": "MGI:2135604", "url": "https://alliancegenome.org/gene/MGI:2135604#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-35", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-35#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9Y692-1", "protein_name": "Glucocorticoid modulatory element-binding protein 1", "gene_name": "GMEB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANAEVSVPVGDVVVVPTEGNEGENPEDTKTQVILQLQPVQQGLFIDGHFYNRIYEAGSENNTAVVAVETHTIHKIEEGIDTGTIEANEDMEIAYPITCGESKAILLWKKFVCPGINVKCVKFNDQLISPKHFVHLAGKSTLKDWKRAIRLGGIMLRKMMDSGQIDFYQHDKVCSNTCRSTKFDLLISSARAPVPGQQTSVVQTPTSADGSITQIAISEESMEEAGLEWNSALTAAVTMATEEGVKKDSEEISEDTLMFWKGIADVGLMEEVVCNIQKEIEELLRGVQQRLIQAPFQVTDAAVLNNVAHTFGLMDTVKKVLDNRRNQVEQGEEQFLYTLTDLERQLEEQKKQGQDHRLKSQTVQNVVLMPVSTPKPPKRPRLQRPASTTVLSPSPPVQQPQFTVISPITITPVGQSFSMGNIPVATLSQGSSPVTVHTLPSGPQLFRYATVVSSAKSSSPDTVTIHPSSSLALLSSTAMQDGSTLGNMTTMVSPVELVAMESGLTSAIQAVESTSEDGQTIIEIDPAPDPEAEDTEGKAVILETELRTEEKVVAEMEEHQHQVHNVEIVVLED", "length": 573 }, "evidence": [ { "id": "HGNC:4370", "url": "https://alliancegenome.org/gene/HGNC:4370#orthology", "database": "AGR" }, { "id": "RGD:1563208", "url": "https://alliancegenome.org/gene/RGD:1563208#orthology", "database": "AGR" }, { "id": "MGI:2135604", "url": "https://alliancegenome.org/gene/MGI:2135604#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-35", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-35#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNH6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 50, "end_pos": 52, "annotation": "n_glycosylation_sequon" }, { "start_pos": 512, "end_pos": 514, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PNH6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNH6" }, { "id": "PS50864", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50864" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAND", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 145, "start_aa": "Glu", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 195 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 28, "end_pos": 30 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 50, "end_pos": 52 }, { "start_pos": 512, "end_pos": 514 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PNI2-1", "uniprot_ac": "A0A8M9PNI2", "uniprot_id": "A0A8M9PNI2_DANRE", "mass": { "chemical_mass": 88643.0, "monoisotopic_mass": 88643.0 }, "refseq": { "ac": "XP_021326444", "name": "von Willebrand factor A domain-containing protein 5A isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326444" }, "gene_names": [ { "name": "si:ch73-265h17.1", "type": "recommended", "evidence": [ { "id": "A0A8M9PNI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNI2" } ] }, { "name": "LOC100535104", "type": "synonym", "evidence": [ { "id": "XP_021326444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326444" }, { "id": "A0A8M9PNI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNI2" } ] } ], "protein_names": [ { "name": "von Willebrand factor A domain-containing protein 5A isoform X3", "type": "synonym", "evidence": [ { "id": "XP_021326444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326444" }, { "id": "A0A8M9PNI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNI2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021326444.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326444", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326444" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNI2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch73-265h17.1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNI2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131121-358", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-358", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PNI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PNI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013694", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013694", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PNI2", "url": "https://www.orthodb.org/?gene=A0A8M9PNI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45737", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45737", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45737:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45737:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08487", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08487", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13768", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13768", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021326444", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326444", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PNI2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PNI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131121-358", "url": "https://zfin.org/ZDB-GENE-131121-358", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVNCGLLTGLNEPVPLKSISVEVRVQDHVASVSSTLQYVNEEQRPLEALFVFPLPADAAVCHFSAKIGEQEIVAELQDKETAKDQYDDAVSSGQQAFLLEESAESPDVFRLSVGCLSPGQNAAVTIIYITELAVQADQSLRFCLPAVLNPRYTPAGSDAGIVSEISSVCGAVPYSLTLSVHVSSPKPISKLESNCTLDPLVFLCSDHTQATVNLSPGHMFDRDVELFLYYQDTHQPSAVVEAGVATAPSGSLMRNPVVMITLYPEFPEEVMSSMATQGEFVFVMDRSGSMDGMMHRGKEAQHRIESAKDTLLLLLKSLPMGCYFNIYGFGSEFESFFPKSVEYSQDTMDQALKRVMEMRADMCGTEILQPLTHIYSQPCIPEHPRQLFIFTDGEVGNTKEVLDLVKSHAHSHRCFSFGIGEGASTALITGLAREGSGHAQFITGRERMQPKAMESLRFALQPAVSNISVDWTLPEGVTAETVSPPIDVLFQGQRTLIYAQLKGKSLGGSEGSVTVKYNLNSQPVSNQLHFCIKPTEETGLVVHRLAARTIIRSLEQKERSSAESKSLRSSIVELSVQAGVSSVHTAFIGINKDTKQTVKGPLQRRRVPTYDYFEDLKCARFLPPRAKRRMPKFQLGALLRMPKFQLGALLRMPKFQFGDVLHGTGQLLAGCSSAVELTSLRYTSLGCGSIRTQEHAAPEPPQDMLLPLVSLQKASGCWELDAALAAVFGKTEDELTNQKPAQVDGSMWATILALIWLYSWRKEQQVEWQFVAQKAAAWIASEKVGDLSQCVCVGNVLLGCQVTKDSLGI", "length": 809, "header": "tr|A0A8M9PNI2-1|A0A8M9PNI2_DANRE Isoform 1 of von Willebrand factor A domain-containing protein 5A isoform X3 OS=Danio rerio OX=7955 GN=si:ch73-265h17.1 PE=4 SV=3 CANONICAL=A0A8M9PNI2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PNI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNI2/entry#A0A8M9PNI2-1", "sequence": { "sequence": "MVNCGLLTGLNEPVPLKSISVEVRVQDHVASVSSTLQYVNEEQRPLEALFVFPLPADAAVCHFSAKIGEQEIVAELQDKETAKDQYDDAVSSGQQAFLLEESAESPDVFRLSVGCLSPGQNAAVTIIYITELAVQADQSLRFCLPAVLNPRYTPAGSDAGIVSEISSVCGAVPYSLTLSVHVSSPKPISKLESNCTLDPLVFLCSDHTQATVNLSPGHMFDRDVELFLYYQDTHQPSAVVEAGVATAPSGSLMRNPVVMITLYPEFPEEVMSSMATQGEFVFVMDRSGSMDGMMHRGKEAQHRIESAKDTLLLLLKSLPMGCYFNIYGFGSEFESFFPKSVEYSQDTMDQALKRVMEMRADMCGTEILQPLTHIYSQPCIPEHPRQLFIFTDGEVGNTKEVLDLVKSHAHSHRCFSFGIGEGASTALITGLAREGSGHAQFITGRERMQPKAMESLRFALQPAVSNISVDWTLPEGVTAETVSPPIDVLFQGQRTLIYAQLKGKSLGGSEGSVTVKYNLNSQPVSNQLHFCIKPTEETGLVVHRLAARTIIRSLEQKERSSAESKSLRSSIVELSVQAGVSSVHTAFIGINKDTKQTVKGPLQRRRVPTYDYFEDLKCARFLPPRAKRRMPKFQLGALLRMPKFQLGALLRMPKFQFGDVLHGTGQLLAGCSSAVELTSLRYTSLGCGSIRTQEHAAPEPPQDMLLPLVSLQKASGCWELDAALAAVFGKTEDELTNQKPAQVDGSMWATILALIWLYSWRKEQQVEWQFVAQKAAAWIASEKVGDLSQCVCVGNVLLGCQVTKDSLGI", "length": 809, "header": "tr|A0A8M9PNI2-1|A0A8M9PNI2_DANRE Isoform 1 of von Willebrand factor A domain-containing protein 5A isoform X3 OS=Danio rerio OX=7955 GN=si:ch73-265h17.1 PE=4 SV=3 CANONICAL=A0A8M9PNI2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M3B6Y1-1", "protein_name": "von Willebrand factor A domain-containing protein 5A isoform X1", "gene_name": "si:ch1073-340j19.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNCGLLSGLNEPVPLKSISVEVRVQDHVASVSSTLQYVNEEQRPLEALFVFPLPADAAVCHFSAKIGEQEIVAELQDKETAKDQYDDAVSSGQQAFLLEESAESPDVFRLSVGCLSPGQNAAVTIIYITELAVQADQSLRFCLPAVLNPRYTPAGSDAGIVSEISSVSGAAPYSLTLSVHVSSPKPISKLESNCTLDPLVFLCSDHTQATVNLSPGHMFDRDVELFLYYQDTHQPSAVVEAGVATAPSDSLMRNPVVMISLYPEFPEEVMSSMATQGEFVFVMDRSGSMSGMMRGKEAQNRIESAKDTLLLLLKSLPMGCYFNIYGFGSRFKSFFPKSVEYNQDKMDQALKEVKEMRADMGGTEILQPLKHIYSQPCIPEHPRQLFIFTDGAVGNTKEVLDLVKSHAHSHRCFSFGIGEGASTALITGLAREGSGHAQFITGSERMQPKVMESLRFALQPIVSNISVDWTLPEGVTAETVAPPIDVLFQGQRTLIYAQLKGNSLGGSEGSVTVKYNLNSQPVTNQLHFCIKPTEETGLVVHRLAARTMIRSLEQKERSSAESESLRSSIVELSVQAGVSSVHTAFIGINKDTKQTVKGPLQQRRVPTYERTSDYHYFYPPQAERREKRCYRLAPPERREKLCYRSAPPDDRMREHCNFASRRERREKLCYRSAPPADWLSFDCVDDEVETQGSEDCVAEKSVCNRLPLRKAAPELQQDLLLPLVSLQKASGCWELDAALAAVLGKTEDELTNQKPAQVDGSVWATLLALIWLYSWRKEQQVEWQFVAQKAAAWITSEKVGDLSQCVCVGNVLLGCQVTKDSLGI", "length": 824 }, "evidence": [ { "id": "RGD:1311744", "url": "https://alliancegenome.org/gene/RGD:1311744#orthology", "database": "AGR" }, { "id": "RGD:735145", "url": "https://alliancegenome.org/gene/RGD:735145#orthology", "database": "AGR" }, { "id": "MGI:1915026", "url": "https://alliancegenome.org/gene/MGI:1915026#orthology", "database": "AGR" }, { "id": "HGNC:6658", "url": "https://alliancegenome.org/gene/HGNC:6658#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A1U8-1", "protein_name": "von Willebrand factor A domain-containing protein 5A", "gene_name": "Vwa5al1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSERSNILRRKALSKPDAVLLELLSYNRAREVGVFSRKIDLQLFSLFLNHSTRISAEVALPRGSTPERIPPSIEALPRPPPATTTASCSGHCQPELSAARQRVSFQLLVLRNHSVNMVSSSGLLTKVREPVVPKSIAVTLSINDFVAGVSATLNYKNEEKTPLETFFVFPMDEDSAVYSFEACVDGKKIVAELEDKYQPHKRYEEAFSGGFQPYLLEEDKCSRDVFCCNVGNLQPGSKVSLTLRYVQELPLEDDGALRYVLPAILNPRYHLSDQCVDSCLDMKTPIVPLEELPYTLSMVANISSKLGISTIQSNCPLNPIEYTGDNKTSAQVSLADGHKFDRDVELLIFYRKVHSPSVAVEMGMPEKPSDSLMGAPSAMVSFYPDIPEVETTTKCGEFVFLMDCSKSMNNPMSSKNKSQLRIDAAKETLILLLKSLPMGCYFNIYGFGATHEEFFPISVKYSQETMEMAVAKVKLLLADLGGTELLTPLRKIVRKPPIPGHPLQIFVFTDGEIVESFSVIREVKFRSRKYRCFTFGIGEGASTSLIKSLALLSGGTAEFITGNDRMQSKALRSLRRSLQSVVEDVTLSWNLPPEMFAPVLAPEQTSIFRGQKIIIYSLFIGKIPQEEATGEVCLSYKLHGKSYEEKMTFSLQPKSDDNFTIHRLAAKSMIQSKDFGFKETAAMYRRDVLDISLDSGIISSFTAFVAINKELNEPIQGPLLHRDILRPILMDGRNRRTSDAYSKIVFCPSVVPVNHLPKWLRKKHHPNGTPQEPQKCYRVKCVIPTDTRPELSHLAKYDSSPQGNKEHSIAQLINLQNADGSWDMNEDLVKILGTSLEDMTAARPSEVLEPSAWATMLAVLWLHENGKELKEEWELLERKAVVWLHKNAVEGFTKAMDTANKFLKTSLSPSIFNL", "length": 915 }, "evidence": [ { "id": "RGD:1311744", "url": "https://alliancegenome.org/gene/RGD:1311744#orthology", "database": "AGR" }, { "id": "HGNC:6658", "url": "https://alliancegenome.org/gene/HGNC:6658#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-358", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-358#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O00534-1", "protein_name": "von Willebrand factor A domain-containing protein 5A", "gene_name": "VWA5A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVHFCGLLTLHREPVPLKSISVSVNIYEFVAGVSATLNYENEEKVPLEAFFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKARTNYEKAISQGHQAFLLEGDSSSRDVFSCNVGNLQPGSKAAVTLKYVQELPLEADGALRFVLPAVLNPRYQFSGSSKDSCLNVKTPIVPVEDLPYTLSMVATIDSQHGIEKVQSNCPLSPTEYLGEDKTSAQVSLAAGHKFDRDVELLIYYNEVHTPSVVLEMGMPNMKPGHLMGDPSAMVSFYPNIPEDQPSNTCGEFIFLMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGCYFNIYGFGSSYEACFPESVKYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFSVIKEVRINRQKHRCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRMQSKALRTLKRSLQPVVEDVSLSWHLPPGLSAKMLSPEQTVIFRGQRLISYAQLTGRMPAAETTGEVCLKYTLQGKTFEDKVTFPLQPKPDVNLTIHRLAAKSLLQTKDMGLRETPASDKKDALNLSLESGVISSFTAFIAINKELNKPVQGPLAHRDVPRPILLGASAPLKIKCQSGFRKALHSDRPPSASQPRGELMCYKAKTFQMDDYSLCGLISHKDQHSPGFGENHLVQLIYHQNANGSWDLNEDLAKILGMSLEEIMAAQPAELVDSSGWATILAVIWLHSNGKDLKCEWELLERKAVAWMRAHAGSTMPSVVKAAITFLKSSVDPAIFAF", "length": 786 }, "evidence": [ { "id": "RGD:1311744", "url": "https://alliancegenome.org/gene/RGD:1311744#orthology", "database": "AGR" }, { "id": "RGD:735145", "url": "https://alliancegenome.org/gene/RGD:735145#orthology", "database": "AGR" }, { "id": "MGI:1915026", "url": "https://alliancegenome.org/gene/MGI:1915026#orthology", "database": "AGR" }, { "id": "HGNC:6658", "url": "https://alliancegenome.org/gene/HGNC:6658#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-358", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-358#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q75WE7-1", "protein_name": "von Willebrand factor A domain-containing protein 5A", "gene_name": "Vwa5a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHHWGLITGNKEKVPLKSISVTLSINDFVAAVAATLHYENEEKVPIEAMFVFPMDEDSAVYSFEALVDGKKIVAELQDKTKAHSKYEEALSQGHQAYLLEEDDYSRDVFSCNVGNLQPGTKVAVTLRYVQELPLESDGALRYLLPAVLNPRYQLSEQSASSCLNVQKPIVPLEALPYTLSMVATITSQHGIERVQSNCSLSPIQYLTDDKTSAQVSLTEGHKFDRDVELLIYYREVHSPSVAVEKGMQDKKRDSLMGAPCAMVSFYPDIPEVNASKVCGEFVFLMDRSGSMQTPMRTEENSQLRIEAAKETLLLLLKSLPMGCYFNIYGFGSSYEQFFPESVKYTQETIEEAVERVKRLDADLGGTEILTPLRNIYKTSSIPGHPLQLFVFTDGEVSDTYSVIREVKLNSKKHRCFSFGIGQGASTSLIKNIARVSGGTAEFITGKDRMQAKALGSLKLALQCALDDISLSWELPPGLSVNMLSPEQPTIFRGQRLIIYAQLTGPMPQAESRGAVCLKHTLQGKSLENKVAFSLQPKENANFTIHRLAAKFLIQTKDLGSHEVSKEEKKDVMNISLQSGVLSSFTAFVAINKELNKPVQGPLAHRVIPRPMIATSTSMFMRSCSRLTGPFKNSRLKRRLCAADYVPYGHESTVYSSMPSPAPIENQGVADSSNEKSNSQNEHKAFGENVVLQLIFLQNANGSWKLDENLTKILGTTLEDTKAANPSQHGDPSAWATILAVLWLHANGQDLKCEWELLERKAVAWLHDHAGRGTTPPPFPSFHLHPREPCLYVLQRTQESLWLSQLCCLRTLSLQLILHFQD", "length": 822 }, "evidence": [ { "id": "RGD:735145", "url": "https://alliancegenome.org/gene/RGD:735145#orthology", "database": "AGR" }, { "id": "MGI:1915026", "url": "https://alliancegenome.org/gene/MGI:1915026#orthology", "database": "AGR" }, { "id": "HGNC:6658", "url": "https://alliancegenome.org/gene/HGNC:6658#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-358", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-358#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q99KC8-1", "protein_name": "von Willebrand factor A domain-containing protein 5A", "gene_name": "Vwa5a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEHHCGLITSNKETVPLKNISVTLSINEFVAAVVATLNYENEEKVPLEATFVFPMDEDSAVYSFEALVDGKKIVAELQDKMKAHSEYEEALSQGHQAYLLEEDDYSRDVFSCNVGNLQPGAKVAVTLRYVQELPLETDGALRYLLPAILNPRYQLSEQSANSCLNIQKPTVPLEDLPYTLNMTATITSQHGIERVQSNCSLSPIQYLTDDKTSAQVSLTEGHKFDRDVELLIYYNEVHSPSVAVEMGMLDMKPDSLMGAPSAMVSFYPDIPEVEASKACGEFVFLMDRSGSMDSPMSTENNSQLRIEAAKETLLLLLKSLPMGCYFNIYGFGSSYEKFFPESVKYTQDTMEDAVKRVKALKANLGGTEILTPLCNIYKASSIPGHPLQLFVFTDGEVSDTFSVIREVKLNSKKHRCFSFGIGQGASTSLIKNIARVSGGTAVFITGKDRMQTKALGSLKFALQCAVDNISLSWDLPPGLSVKMLSPEQLTIFRGQRLIIYAQLTGLMPQVESTGAVCLKHILQGRSLENRVTFSLQPKANDNFTIHRLAAKSLIQTKDFGSQEASKEEKEDVMNISLQSGVLSSFTAFIAINKELNKPVQGPLAHRVIPRPVMAGSSSMRFYSSFSGGFKGPQPRSLRVPAYDLCSAESANLVLKKSACSAIQKKKTNSSTNKSNLKKEHKAFGENAVVQLISLQKANGSWELDEDLTKILGTKSKDIKAANPAKHEDPSAWSTVLAVVWLHANGTDLKCEWELLERKAVAWLHDHAGSSIPMLVQAANSLLKLSVNPAVFGV", "length": 793 }, "evidence": [ { "id": "RGD:735145", "url": "https://alliancegenome.org/gene/RGD:735145#orthology", "database": "AGR" }, { "id": "MGI:1915026", "url": "https://alliancegenome.org/gene/MGI:1915026#orthology", "database": "AGR" }, { "id": "HGNC:6658", "url": "https://alliancegenome.org/gene/HGNC:6658#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-358", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-358#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 213, "end_pos": 215, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PNI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNI2" }, { "id": "PS51468", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51468" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VIT", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 130, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PNI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNI2" }, { "id": "PS50234", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50234" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "VWFA", "eco_id": "ECO_0000259", "start_pos": 279, "end_pos": 456, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 194, "end_pos": 196 }, { "start_pos": 213, "end_pos": 215 }, { "start_pos": 466, "end_pos": 468 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PNQ2-1", "uniprot_ac": "A0A8M9PNQ2", "uniprot_id": "A0A8M9PNQ2_DANRE", "mass": { "chemical_mass": 51692.0, "monoisotopic_mass": 51692.0 }, "refseq": { "ac": "XP_021326509", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326509" }, "gene_names": [ { "name": "LOC101884989", "type": "recommended", "evidence": [ { "id": "A0A8M9PNQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ] }, { "name": "LOC101884989", "type": "synonym", "evidence": [ { "id": "XP_021326509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326509" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PNQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021326509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326509" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021326509.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021326509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326509" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101884989", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2", "locus": {} } ], "crossref": [ { "id": "A0A8M9PNQ2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PNQ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00276", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00276", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101884989", "url": "https://www.ncbi.nlm.nih.gov/gene/101884989", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101884989", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884989", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HWKEMCN", "url": "https://omabrowser.org/oma/group/HWKEMCN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PNQ2", "url": "https://www.orthodb.org/?gene=A0A8M9PNQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10024:SF351", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10024:SF351", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021326509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021326509", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PNQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW61", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW61-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW65", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW65-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW71", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW71-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW86", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HW86-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HW86-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKVPLEVHLQILLAVGLAVLCFCLLIGCIFCYYHSKLHPKDDKEAELSVPPPSADHVTITLSPSPSIITQPIKQQYEELDGDVLDFPSINSSSEDDISMTSLPGPQKSRFSLRRLSSPVITCKLGKPAIRGRSSLPTIPKLSLSVKSHSRVDDDSNSENSKIKVYNDRHYGSSRSTPSISFTLLYSSSNSRLTVSVLGVFRGSRRLSGMQVTACLPPLCPETLQAGRKQRRRRSLSAECPAQVFSLQVWSVQELQTCTLRLSISSRDFSGLRETPLGELEMSCAEIQWESDHTFSLTRQLNPARRKLRKSQSCQAAVGAPVSLLRSLGQILILLQYQSLAHRIKVMVRKAQNLPKLSRMPGTPDHSVIINLLQDGTVISTKETKCSSGLNPVWNAPFLFDLPAGDVSTLMLEFIIMQGRLYAKSCVLGRVLIGCEVSEAGNQHWREMRNTPQVETACWHLIQQDTP", "length": 466, "header": "tr|A0A8M9PNQ2-1|A0A8M9PNQ2_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101884989 PE=3 SV=3 CANONICAL=A0A8M9PNQ2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PNQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2/entry#A0A8M9PNQ2-1", "sequence": { "sequence": "MKVPLEVHLQILLAVGLAVLCFCLLIGCIFCYYHSKLHPKDDKEAELSVPPPSADHVTITLSPSPSIITQPIKQQYEELDGDVLDFPSINSSSEDDISMTSLPGPQKSRFSLRRLSSPVITCKLGKPAIRGRSSLPTIPKLSLSVKSHSRVDDDSNSENSKIKVYNDRHYGSSRSTPSISFTLLYSSSNSRLTVSVLGVFRGSRRLSGMQVTACLPPLCPETLQAGRKQRRRRSLSAECPAQVFSLQVWSVQELQTCTLRLSISSRDFSGLRETPLGELEMSCAEIQWESDHTFSLTRQLNPARRKLRKSQSCQAAVGAPVSLLRSLGQILILLQYQSLAHRIKVMVRKAQNLPKLSRMPGTPDHSVIINLLQDGTVISTKETKCSSGLNPVWNAPFLFDLPAGDVSTLMLEFIIMQGRLYAKSCVLGRVLIGCEVSEAGNQHWREMRNTPQVETACWHLIQQDTP", "length": 466, "header": "tr|A0A8M9PNQ2-1|A0A8M9PNQ2_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101884989 PE=3 SV=3 CANONICAL=A0A8M9PNQ2-1" }, "locus": {} }, { "isoform_ac": "A0AC58HW61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2/entry#A0AC58HW61-1", "sequence": { "sequence": "MMIQIRKTARLSRLTVSVLGVFRGSRRLSGMQVTACLPPLCPETLQAGRKQRRRRSLSAECPAQVFSLQVWSVQELQTCTLRLSISSRDFSGLRETPLGELEMSCAEIQWESDHTFSLTRQLNPARRKLRKSQSCQAAVGAPVSLLRSLGQILILLQYQSLAHRIKVMVRKAQNLPKLSRMPGTPDHSVIINLLQDGTVISTKETKCSSGLNPVWNAPFLFDLPAGDVSTLMLEFIIMQGRLYAKSCVLGRVLIGCEVSEAGNQHWREMRNTPQVETACWHLIQQDTP", "length": 288, "header": "tr|A0AC58HW61-1|A0AC58HW61_DANRE Computationally mapped isoform of Synaptotagmin-4 isoform X3 OS=Danio rerio OX=7955 GN=LOC101884989 PE=3 SV=1 CANONICAL=A0A8M9PNQ2-1" }, "locus": {} }, { "isoform_ac": "A0AC58HW65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2/entry#A0AC58HW65-1", "sequence": { "sequence": "MTSLPGPQKSRFSLRRLSSPVITCKLGKPAIRGRSSLPTIPKLSLSVKSHSRVDDDSNSENSKIKVYNDRHYGSSRSTPSISFTLLYSSSNSRLTVSVLGVFRGSRRLSGMQVTACLPPLCPETLQAGRKQRRRRSLSAECPAQVFSLQVWSVQELQTCTLRLSISSRDFSGLRETPLGELEMSCAEIQWESDHTFSLTRQLNPARRKLRKSQSCQAAVGAPVSLLRSLGQILILLQYQSLAHRIKVMVRKAQNLPKLSRMPGTPDHSVIINLLQDGTVISTKETKCSSGLNPVWNAPFLFDLPAGDVSTLMLEFIIMQGRLYAKSCVLGRVLIGCEVSEAGNQHWREMRNTPQVETACWHLIQQDTP", "length": 368, "header": "tr|A0AC58HW65-1|A0AC58HW65_DANRE Computationally mapped isoform of Synaptotagmin-4 isoform X2 OS=Danio rerio OX=7955 GN=LOC101884989 PE=3 SV=1 CANONICAL=A0A8M9PNQ2-1" }, "locus": {} }, { "isoform_ac": "A0AC58HW71-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2/entry#A0AC58HW71-1", "sequence": { "sequence": "MMIQIRKTARLRLTVSVLGVFRGSRRLSGMQVTACLPPLCPETLQAGRKQRRRRSLSAECPAQVFSLQVWSVQELQTCTLRLSISSRDFSGLRETPLGELEMSCAEIQWESDHTFSLTRQLNPARRKLRKSQSCQAAVGAPVSLLRSLGQILILLQYQSLAHRIKVMVRKAQNLPKLSRMPGTPDHSVIINLLQDGTVISTKETKCSSGLNPVWNAPFLFDLPAGDVSTLMLEFIIMQGRLYAKSCVLGRVLIGCEVSEAGNQHWREMRNTPQVETACWHLIQQDTP", "length": 287, "header": "tr|A0AC58HW71-1|A0AC58HW71_DANRE Computationally mapped isoform of Synaptotagmin-4 isoform X4 OS=Danio rerio OX=7955 GN=LOC101884989 PE=3 SV=1 CANONICAL=A0A8M9PNQ2-1" }, "locus": {} }, { "isoform_ac": "A0AC58HW86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2/entry#A0AC58HW86-1", "sequence": { "sequence": "MMIQIRKTARLRRLSGMQVTACLPPLCPETLQAGRKQRRRRSLSAECPAQVFSLQVWSVQELQTCTLRLSISSRDFSGLRETPLGELEMSCAEIQWESDHTFSLTRQLNPARRKLRKSQSCQAAVGAPVSLLRSLGQILILLQYQSLAHRIKVMVRKAQNLPKLSRMPGTPDHSVIINLLQDGTVISTKETKCSSGLNPVWNAPFLFDLPAGDVSTLMLEFIIMQGRLYAKSCVLGRVLIGCEVSEAGNQHWREMRNTPQVETACWHLIQQDTP", "length": 274, "header": "tr|A0AC58HW86-1|A0AC58HW86_DANRE Computationally mapped isoform of Synaptotagmin-4 isoform X5 OS=Danio rerio OX=7955 GN=LOC101884989 PE=3 SV=1 CANONICAL=A0A8M9PNQ2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 176, "start_aa": "Thr", "end_pos": 176, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr176", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "reported site T78 is on non-canonical isoform A0AC58HW61-1 which maps to canonical isoform site A0A8M9PNQ2-1:256", "icn3d_view": {}, "start_pos": 256, "start_aa": "Thr", "end_pos": 256, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr256", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101884989", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884989", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 5, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "pmid": "" }, { "name": "synapse", "id": "GO:0045202", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045202", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "pmid": "" }, { "name": "exocytic vesicle", "id": "GO:0070382", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070382", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "pmid": "" }, { "name": "presynapse", "id": "GO:0098793", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098793", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "pmid": "" }, { "name": "regulation of calcium ion-dependent exocytosis", "id": "GO:0017158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017158", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "pmid": "" }, { "name": "vesicle fusion", "id": "GO:0006906", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006906", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "pmid": "" }, { "name": "calcium-dependent activation of synaptic vesicle fusion", "id": "GO:0099502", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099502", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "pmid": "" }, { "name": "SNARE binding", "id": "GO:0000149", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000149", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "pmid": "" }, { "name": "calcium ion sensor activity", "id": "GO:0061891", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061891", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PNQ2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PNQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PNQ2" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 326, "end_pos": 459, "start_aa": "Ser", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 176, 256 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PP03-1", "uniprot_ac": "A0A8M9PP03", "uniprot_id": "A0A8M9PP03_DANRE", "mass": { "chemical_mass": 12220.0, "monoisotopic_mass": 12220.0 }, "refseq": { "ac": "XP_021328778", "name": "beta-microseminoprotein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328778" }, "gene_names": [ { "name": "LOC108179705", "type": "recommended", "evidence": [ { "id": "A0A8M9PP03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP03" } ] }, { "name": "LOC108179705", "type": "synonym", "evidence": [ { "id": "XP_021328778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328778" } ] } ], "protein_names": [ { "name": "Beta-microseminoprotein", "type": "synonym", "evidence": [ { "id": "A0A8M9PP03", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP03/entry#names_and_taxonomy" } ] }, { "name": "beta-microseminoprotein", "type": "synonym", "evidence": [ { "id": "XP_021328778", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328778" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328778" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PP03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP03" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108179705", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP03", "locus": {} } ], "crossref": [ { "id": "A0A8M9PP03", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PP03", "database": "AlphaFoldDB", "categories": [] }, { "id": "108179705", "url": "https://www.ncbi.nlm.nih.gov/gene/108179705", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108179705", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179705", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PF05825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021328778", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328778", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PP03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP03", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PP03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP03-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRLFVLFAAVTYCYACRLETFPEDTNNNPQGCSDSDGNLHEFNSEWENGPETCVCVDFGIICCERTWETFGTPVPTEPTTIIGDYFEDLYGDNNHGADNTEGSGGEAQEK", "length": 110, "header": "tr|A0A8M9PP03-1|A0A8M9PP03_DANRE Isoform 1 of Beta-microseminoprotein OS=Danio rerio OX=7955 GN=LOC108179705 PE=3 SV=1 CANONICAL=A0A8M9PP03-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PP03-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP03/entry#A0A8M9PP03-1", "sequence": { "sequence": "MRLFVLFAAVTYCYACRLETFPEDTNNNPQGCSDSDGNLHEFNSEWENGPETCVCVDFGIICCERTWETFGTPVPTEPTTIIGDYFEDLYGDNNHGADNTEGSGGEAQEK", "length": 110, "header": "tr|A0A8M9PP03-1|A0A8M9PP03_DANRE Isoform 1 of Beta-microseminoprotein OS=Danio rerio OX=7955 GN=LOC108179705 PE=3 SV=1 CANONICAL=A0A8M9PP03-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108179705", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179705", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PP03", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP03" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PP29-1", "uniprot_ac": "A0A8M9PP29", "uniprot_id": "A0A8M9PP29_DANRE", "mass": { "chemical_mass": 111272.0, "monoisotopic_mass": 111272.0 }, "refseq": { "ac": "XP_021322955", "name": "adhesion G-protein coupled receptor F3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322955" }, "gene_names": [ { "name": "adgrf3a", "type": "recommended", "evidence": [ { "id": "A0A8M9PP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29" } ] }, { "name": "adgrf3a", "type": "synonym", "evidence": [ { "id": "XP_021322955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322955" } ] } ], "protein_names": [ { "name": "Adhesion G-protein coupled receptor F3 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29/entry#names_and_taxonomy" } ] }, { "name": "adhesion G-protein coupled receptor F3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322955" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021322955.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322955" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PP29", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "adgrf3a", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131121-607", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-607", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PP29", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PP29", "database": "AlphaFoldDB", "categories": [] }, { "id": "101886922", "url": "https://www.ncbi.nlm.nih.gov/gene/101886922", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017981", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017981", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046338", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046338", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101886922", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886922", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PP29", "url": "https://www.orthodb.org/?gene=A0A8M9PP29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45813", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45813", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45813:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45813:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01825", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01825", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021322955", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322955", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PP29", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PP29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQD5", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQD5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQD5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQD5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQE8", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQE8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQE8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQE8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131121-607", "url": "https://zfin.org/ZDB-GENE-131121-607", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLSRFCFPEKSTLIYYIELEFESTVDVNVTAFLDQLKRIDLSKATVKQFNPTTNCNLTETNKQCQCMPGYKWSDDMDCTNECELNINTTAVCLSSNKVSIDGTTTDTSMDCSLLCDQSKVNSAEHKKLLQNRTTMLVEKYSTLDYFNSLVITGYGWGSLVLNYTVIYLGPVSIDDLQKVVLQVDNTKLVTKGLIDIKINNSQPVDIYSSATIICTPPPNIGSVTVKWYLTNSQNKTTEITDGIEATLTTNQNKISTVQLNNFSESWKGTFKCVYAIYGISHTASEQLDVALLPNIQALSNPQFPICTSLSSTSFKVYCNISADSENYTVTWNHSTSSTTVDTAGNRISYIAYVTILCDSKETLNVACTFINTRSKNNLNRTQNVQIPIIYAYSTVCDPEGGWPIAKSGYTATMPCDNSGVGWRTRKCNGTRWSTEISTCVNANLFDIKTDVQELNKGIGFIKDNADQLFQRINDSTTLRTFTFPNIETSVNIFGVMNDVSTRQQNQWNDTVMSKLVSSASNLLNDPSGWQNPENKSIFISVEYLKTIERMMNNSNLISNTPYISSNAQMALCNHTSPADICKTFNASVRNSDNSVVVFGFRNLYQILPKAEGNDSNTTILSVTPVNANNTNRSITLEFDSAKQRLPNHMIYCVYWDENLNEWSSDGCRWAGVDNPTLCICDHNSAFTILMSKNAETLPYMDELTYAGLGISILSLLACLIIKVLVWDAVVKSPISNFRHVALFNISLCLLLAHCMFLTTSKPESIPPNWCSILTLIKHFFFLAVFFWMLCLSFVLLHQMIYVFDRLRKKVFLGLSITVGYACPIIAVAVTYISFNNGAEGEYYSKSTCWLTYKGTLKGSIFAFIIPIGAIVFVNLFTLAVVIMKIATPSISEAKARDEKDVAKSMIKTIVFLSPVLGLSWVLGFFVLGLDLTVKPWAALVNYSFTIFNSLQGLFILLTNCVGEKKVRDALLKRFKIKQSVHSKTESSSKAQSSIMRK", "length": 997, "header": "tr|A0A8M9PP29-1|A0A8M9PP29_DANRE Isoform 1 of Adhesion G-protein coupled receptor F3 isoform X1 OS=Danio rerio OX=7955 GN=adgrf3a PE=3 SV=3 CANONICAL=A0A8M9PP29-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PP29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29/entry#A0A8M9PP29-1", "sequence": { "sequence": "MLSRFCFPEKSTLIYYIELEFESTVDVNVTAFLDQLKRIDLSKATVKQFNPTTNCNLTETNKQCQCMPGYKWSDDMDCTNECELNINTTAVCLSSNKVSIDGTTTDTSMDCSLLCDQSKVNSAEHKKLLQNRTTMLVEKYSTLDYFNSLVITGYGWGSLVLNYTVIYLGPVSIDDLQKVVLQVDNTKLVTKGLIDIKINNSQPVDIYSSATIICTPPPNIGSVTVKWYLTNSQNKTTEITDGIEATLTTNQNKISTVQLNNFSESWKGTFKCVYAIYGISHTASEQLDVALLPNIQALSNPQFPICTSLSSTSFKVYCNISADSENYTVTWNHSTSSTTVDTAGNRISYIAYVTILCDSKETLNVACTFINTRSKNNLNRTQNVQIPIIYAYSTVCDPEGGWPIAKSGYTATMPCDNSGVGWRTRKCNGTRWSTEISTCVNANLFDIKTDVQELNKGIGFIKDNADQLFQRINDSTTLRTFTFPNIETSVNIFGVMNDVSTRQQNQWNDTVMSKLVSSASNLLNDPSGWQNPENKSIFISVEYLKTIERMMNNSNLISNTPYISSNAQMALCNHTSPADICKTFNASVRNSDNSVVVFGFRNLYQILPKAEGNDSNTTILSVTPVNANNTNRSITLEFDSAKQRLPNHMIYCVYWDENLNEWSSDGCRWAGVDNPTLCICDHNSAFTILMSKNAETLPYMDELTYAGLGISILSLLACLIIKVLVWDAVVKSPISNFRHVALFNISLCLLLAHCMFLTTSKPESIPPNWCSILTLIKHFFFLAVFFWMLCLSFVLLHQMIYVFDRLRKKVFLGLSITVGYACPIIAVAVTYISFNNGAEGEYYSKSTCWLTYKGTLKGSIFAFIIPIGAIVFVNLFTLAVVIMKIATPSISEAKARDEKDVAKSMIKTIVFLSPVLGLSWVLGFFVLGLDLTVKPWAALVNYSFTIFNSLQGLFILLTNCVGEKKVRDALLKRFKIKQSVHSKTESSSKAQSSIMRK", "length": 997, "header": "tr|A0A8M9PP29-1|A0A8M9PP29_DANRE Isoform 1 of Adhesion G-protein coupled receptor F3 isoform X1 OS=Danio rerio OX=7955 GN=adgrf3a PE=3 SV=3 CANONICAL=A0A8M9PP29-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQD5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29/entry#A0AC58HQD5-1", "sequence": { "sequence": "MPGYKWSDDMDCTNECELNINTTAVCLSSNKVSIDGTTTDTSMDCSLLCDQSKVNSAEHKKLLQNRTTMLVEKYSTLDYFNSLVITGYGWGSLVLNYTVIYLGPVSIDDLQKVVLQVDNTKLVTKGLIDIKINNSQPVDIYSSATIICTPPPNIGSVTVKWYLTNSQNKTTEITDGIEATLTTNQNKISTVQLNNFSESWKGTFKCVYAIYGISHTASEQLDVALLPNIQALSNPQFPICTSLSSTSFKVYCNISADSENYTVTWNHSTSSTTVDTAGNRISYIAYVTILCDSKETLNVACTFINTRSKNNLNRTQNVQIPIIYAYSTVCDPEGGWPIAKSGYTATMPCDNSGVGWRTRKCNGTRWSTEISTCVNANLFDIKTDVQELNKGIGFIKDNADQLFQRINDSTTLRTFTFPNIETSVNIFGVMNDVSTRQQNQWNDTVMSKLVSSASNLLNDPSGWQNPENKSIFISVEYLKTIERMMNNSNLISNTPYISSNAQMALCNHTSPADICKTFNASVRNSDNSVVVFGFRNLYQILPKAEGNDSNTTILSVTPVNANNTNRSITLEFDSAKQRLPNHMIYCVYWDENLNEWSSDGCRWAGVDNPTLCICDHNSAFTILMSKNAETLPYMDELTYAGLGISILSLLACLIIKVLVWDAVVKSPISNFRHVALFNISLCLLLAHCMFLTTSKPESIPPNWCSILTLIKHFFFLAVFFWMLCLSFVLLHQMIYVFDRLRKKVFLGLSITVGYACPIIAVAVTYISFNNGAEGEYYSKSTCWLTYKGTLKGSIFAFIIPIGAIVFVNLFTLAVVIMKIATPSISEAKARDEKDVAKSMIKTIVFLSPVLGLSWVLGFFVLGLDLTVKPWAALVNYSFTIFNSLQGLFILLTNCVGEKKVRDALLKRFKIKQSVHSKTESSSKAQSSIMRK", "length": 931, "header": "tr|A0AC58HQD5-1|A0AC58HQD5_DANRE Computationally mapped isoform of Adhesion G-protein coupled receptor F3 isoform X3 OS=Danio rerio OX=7955 GN=adgrf3a PE=3 SV=1 CANONICAL=A0A8M9PP29-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQE8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29/entry#A0AC58HQE8-1", "sequence": { "sequence": "MPCDNSGVGWRTRKCNGTRWSTEISTCVNANLFDIKTDVQELNKGIGFIKDNADQLFQRINDSTTLRTFTFPNIETSVNIFGVMNDVSTRQQNQWNDTVMSKLVSSASNLLNDPSGWQNPENKSIFISVEYLKTIERMMNNSNLISNTPYISSNAQMALCNHTSPADICKTFNASVRNSDNSVVVFGFRNLYQILPKAEGNDSNTTILSVTPVNANNTNRSITLEFDSAKQRLPNHMIYCVYWDENLNEWSSDGCRWAGVDNPTLCICDHNSAFTILMSKNAETLPYMDELTYAGLGISILSLLACLIIKVLVWDAVVKSPISNFRHVALFNISLCLLLAHCMFLTTSKPESIPPNWCSILTLIKHFFFLAVFFWMLCLSFVLLHQMIYVFDRLRKKVFLGLSITVGYACPIIAVAVTYISFNNGAEGEYYSKSTCWLTYKGTLKGSIFAFIIPIGAIVFVNLFTLAVVIMKIATPSISEAKARDEKDVAKSMIKTIVFLSPVLGLSWVLGFFVLGLDLTVKPWAALVNYSFTIFNSLQGLFILLTNCVGEKKVRDALLKRFKIKQSVHSKTESSSKAQSSIMRK", "length": 585, "header": "tr|A0AC58HQE8-1|A0AC58HQE8_DANRE Computationally mapped isoform of Adhesion G-protein coupled receptor F3 isoform X2 OS=Danio rerio OX=7955 GN=adgrf3a PE=3 SV=1 CANONICAL=A0A8M9PP29-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101886922", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886922", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MKI0-1", "protein_name": "Adhesion G protein-coupled receptor F3", "gene_name": "Adgrf3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSLALSQLLLAMTLTLLELESTFVPTAQSELSLSGGKSVQQLNQFSRVGESVLVTSYVHLEFSNRALPPKLSENFTLPTVLAFFSSRMITALVLTTECHVDHSGTSFCTCHPDYQWNTTLCSLYPNCCGHRSERDSCECLSFHGPVPGYCQLLPPVPANLTLDSQLQMHRNTLNLILLKKEKATNLRWYLRQSENHRPILLWPGTNVFQTSNESQAGLQIAHMSRHWTGEYESIFEAQGFRRRLRQVVKMPLEEKDVVRLPEELSISCAASTGFQLRCCIPLTNMAYTATWSPGEDSQASLQNMPDSQCFVLAVRHCPAANTTYTCTLQSQSLAPLVAPVSITIIQDGDTTCPEDFSVVAWNVTKAGFMAQAPCPMNKTGVVKRLCGSNGIWGPVQDSCTEAKILDLYSKAKLLLEGQGKPNEQVPRILRELQRQVGVVSTPSDLREMLHTVTLLAKVVAETSTELTDRALKDLLTTTDKILDVNISSLWTLARAQEPSMGSDFLKAVETLVHSVSPQQHPFSFSSSNVLLQSQLLRHSSPLGYQMPSAPPLLQARIPWHSLAPLVLNGTNVRITSLALQKLDSRLPSNYRQGLRDTSYATPGMILVISITADGQDFTQAEVIMDFEDMNGTLHCVFWDHNAFQGRGGWSDEGCELQAANASAVQCVCRHLTAFSILMSQHAVPEDPLLDLLSQVGVGASILALLVCLVIYRLVWRVVVRNKVAFFRHTALFNMVICLLVADTCFLGNPWLPSGYHSLVCLATAFLCHFFYLATFFWMLAQALVLAHQLLFVFHQLSKPLVLSMMSILGYLCPLGFAGVTLGLYLPQRKYLREGKCLLSGDGVSLHAFSEPVLAIVSVNGLVLVIAVLKLLRPSLSEGPAVEKRQALVGVLKALLILTPIFGLTWGLGVTTLFEGSLVFHYIFVILNSLQGVFIFVFGCLTDKKVLEALRKWLRGSRSSNSAISMVTNESCTSEHSRERSELASYEEQMAD", "length": 992 }, "evidence": [ { "id": "RGD:1305868", "url": "https://alliancegenome.org/gene/RGD:1305868#orthology", "database": "AGR" }, { "id": "MGI:2685887", "url": "https://alliancegenome.org/gene/MGI:2685887#orthology", "database": "AGR" }, { "id": "HGNC:18989", "url": "https://alliancegenome.org/gene/HGNC:18989#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-607", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-607#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8N7UVY3-1", "protein_name": "Adhesion G protein-coupled receptor F5 isoform X1", "gene_name": "adgrf3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHTVRIKTLSGAGMLLFAALFIISQTSQAGSTDVTYWAEVMIEGNKTLNVADYLPGLIGTVLDTGVTITGAEIAAECEIVGQNTTCWCGPGYVWSNYVCDNVNKCCNVYQCVANISNFTPLCLPIANVSLIGTLTGSSSSVQTMLTNAFNVLNAFNSLTMQASLLTGLNTYSHNFTVSLGAVFATSKVQGIITTLLTNPAIYTLNVKTLGLVYIEAPAGKLCYNSRQQLNCTSIEAMSKCVWQMSRGDEAPLTLGPGSEIMLSDTCTEMSAVTLLKTNGYWSGTYSCLFVTDNVAHMAMAPVDIALLPEASNVTSNPQTIDCSASSTTKVTITCSIFNSTETYKSQLKLGSMENLTPTKLESNGLIKYSADFTVNCLATGKPPSLTASCVLVNSLNQQRNFSASVSVIYPNDLFCAAEVISTRTWPKTKNNDTAVIDCTATGRQGTLTRKCNGKTWGQEVSLCVKAFLSNVASQASDFEKGLGATQGGAQYIFQSLKNNTASEEDGENSFGDISTAVNVFQTMKAASVNVPLGENLLPDFLESASSILNGSWEVGDKTQSGALASQYLSSVEGLVKSIRINTSEGYNASNIQLQVCKGGSGCNKTIFNVDIEVNATADMVKTVGLQSLANLLPKVGYENSLFPSIVVSSTVENNTQASVNIRLAFPNEEGINAAMQCVFWNVSEERWSDEGCVYVKGRGGEGYCQCNHLTSFSMLMSKYPISMPFLDQLTYIGLGVSICSLLAYIIIEFLVWSAVVKSNLSHFRHTALVNIALSLLLADCSFLASSFPSILNETLCLVLVVAKHYFFLAMFFWMLCLSLMLVHQLIFVFSRIGKKVYMILGFTIGYFCPTVTVAVTYVYYEEATSIPYYSSKTCWLTYQSPMQGSIHAFLFPVGTIVLVNMCSMLVVIATVLKPSGAETNKKGDKDAAKSIIKVILFLTPVFGGTWILGLFVFLIDDSSQFITYLVNYLFTILNSLQGFFILLTGCFAEKRVRDEILKIIVGKSAKEQNTTTSVAK", "length": 1016 }, "evidence": [ { "id": "RGD:1305868", "url": "https://alliancegenome.org/gene/RGD:1305868#orthology", "database": "AGR" }, { "id": "MGI:2685887", "url": "https://alliancegenome.org/gene/MGI:2685887#orthology", "database": "AGR" }, { "id": "HGNC:18989", "url": "https://alliancegenome.org/gene/HGNC:18989#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q58Y75-1", "protein_name": "Adhesion G protein-coupled receptor F3", "gene_name": "ADGRF3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLALSQLLLAVTLPLLELEPTFVPTAQSELSPYGGKSGQQLNQYSGEGESVLVSSYVHLEFSSTAWPQELSKNFTLPTALAVLPPKTLTGLGLTTECRANHSGTSLCTCHPGYQWNATLCSLYPHCWGRRSERDSCMCRSFHGPVTGYCQLLPPVPANLILDSQLQMHGNTLNLILLKKEEATNLRWFLRHSKNHTPISLWPGTNVLQTSSEGQSGLRVARMSRHWAGEYESIFEAQGFRWRLRQLVKVPLQEEEVVRLPDALSISCTASTGFQLSCCIPLTTDYTATWSPGEDSQASLQKMSDSQCFVLAVPHCPATNTTYTCTLQSQNLPPLVAPVSITIIQDGDTTCPEDFSVVSWNVTKAGFVAQAPCPVNKKGVVKRLCGTDGIWRPVQNTCTEAKILTLCLKAKLLEGQGKPYEEVPWILSELQEQVGVASTPSDLWEMLHTVTLLAKVVAETSTELTGSALKDLLTTTDKILDANISALWTLAQAQEPSMGSDFLKAVETLVHSLRPQQHPFSFSSANVLLQSQLLRHSSPPGYQMSFSTWPLLQARIPWHSLAPLVHSGTNVSITSLVLQKLDYRLPSNYTQGLWNTPYTTPGLILVVSITADGQAFTQAEVIMDYEDMNGTLHCVFWDHRVFQGQGGWSDEGCEVHAANASITQCICQHLTAFSILMSQHTVPENPTLDLLSQVGTGASVLALLVCLAIYGLVWRVVVRNKVAFFRHTTLFNMVICLLVADTCFLGSPFLPSGYHSLICLVTAFLCHFFYLATFFWMLAQALVLAHQLLFVFHQLSKHVVLSLMVMLGYLCPLGFAGVTLGLYLPQRKYLWEGKCFLNGGGVMLYSFSEPVLAIVGVNGLVLVIAVLKLLRPSLSEGPTVEKRQALVGVLKALLILTPIFGLTWGLGVATLFDGSIVSHYAFSILNSLQGVFILVFGCLTDKKVLEALRKRLRGSRSSNSAISMVTNETYTSEHSKERSEPASYEERMTD", "length": 991 }, "evidence": [ { "id": "RGD:1305868", "url": "https://alliancegenome.org/gene/RGD:1305868#orthology", "database": "AGR" }, { "id": "MGI:2685887", "url": "https://alliancegenome.org/gene/MGI:2685887#orthology", "database": "AGR" }, { "id": "HGNC:18989", "url": "https://alliancegenome.org/gene/HGNC:18989#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-607", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-607#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZF5-1", "protein_name": "Adhesion G protein-coupled receptor F3", "gene_name": "ADGRF3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVCSAAPLLLLATTLPLLGSPVAQASQPVSETGVRPREGLQRRQWGPLIGRDKAWNERIDRPFPACPIPLSSSFGRWPKGQTMWAQTSTLTLTEEELGQSQAGGESGSGQLLDQENGAGESALVSVYVHLDFPDKTWPPELSRTLTLPAASASSSPRPLLTGLRLTTECNVNHKGNFYCACLSGYQWNTSICLHYPPCQSLHNHQPCGCLVFSHPEPGYCQLLPPGSPVTCLPAVPGILNLNSQLQMPGDTLSLTLHLSQEATNLSWFLRHPGSPSPILLQPGTQVSVTSSHGQAALSVSNMSHHWAGEYMSCFEAQGFKWNLYEVVRVPLKATDVARLPYQLSISCATSPGFQLSCCIPSTNLAYTAAWSPGEGSKASSFNESGSQCFVLAVQRCPMADTTYACDLQSLGLAPLRVPISITIIQDGDITCPEDASVLTWNVTKAGHVAQAPCPESKRGIVRRLCGADGVWGPVHSSCTDARLLALFTRTKLLQAGQGSPAEEVPQILAQLPGQAAEASSPSDLLTLLSTMKYVAKVVAEARIQLDRRALKNLLIATDKVLDMDTRSLWTLAQARKPWAGSTLLLAVETLACSLCPQDHPFAFSLPNVLLQSQLFGPTFPADYSISFPTRPPLQAQIPRHSLAPLVRNGTEISITSLVLRKLDHLLPSNYGQGLGDSLYATPGLVLVISIMAGDRAFSQGEVIMDFGNTDGSPHCVFWDHSLFQGRGGWSKEGCQAQVASASPTAQCLCQHLTAFSVLMSPHTVPEEPALALLTQVGLGASILALLVCLGVYWLVWRVVVRNKISYFRHAALLNMVFCLLAADTCFLGAPFLSPGPRSPLCLAAAFLCHFLYLATFFWMLAQALVLAHQLLFVFHQLAKHRVLPLMVLLGYLCPLGLAGVTLGLYLPQGQYLREGECWLDGKGGALYTFVGPVLAIIGVNGLVLAMAMLKLLRPSLSEGPPAEKRQALLGVIKALLILTPIFGLTWGLGLATLLEEVSTVPHYIFTILNTLQGVFILLFGCLMDRKIQEALRKRFCRAQAPSSTISLVSCCLQILSCASKSMSEGIPWPSSEDMGTARS", "length": 1079 }, "evidence": [ { "id": "RGD:1305868", "url": "https://alliancegenome.org/gene/RGD:1305868#orthology", "database": "AGR" }, { "id": "MGI:2685887", "url": "https://alliancegenome.org/gene/MGI:2685887#orthology", "database": "AGR" }, { "id": "HGNC:18989", "url": "https://alliancegenome.org/gene/HGNC:18989#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-607", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-607#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PP29", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell surface receptor signaling pathway", "id": "GO:0007166", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007166", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PP29", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29" } ], "pmid": "" }, { "name": "adenylate cyclase-activating G protein-coupled receptor signaling pathway", "id": "GO:0007189", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007189", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PP29", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PP29", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 28, "end_pos": 30, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" }, { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 585, "end_pos": 587, "annotation": "n_glycosylation_sequon" }, { "start_pos": 613, "end_pos": 615, "annotation": "n_glycosylation_sequon" }, { "start_pos": 616, "end_pos": 618, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" }, { "start_pos": 631, "end_pos": 633, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" }, { "start_pos": 87, "end_pos": 89, "annotation": "n_glycosylation_sequon" }, { "start_pos": 941, "end_pos": 943, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29" }, { "id": "PS50261", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50261" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 2 profile 2", "eco_id": "ECO_0000259", "start_pos": 700, "end_pos": 963, "start_aa": "Met", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29" }, { "id": "PS50221", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50221" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "GAIN-B", "eco_id": "ECO_0000259", "start_pos": 552, "end_pos": 696, "start_aa": "Asn", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PP29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP29" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 293, "end_pos": 385, "start_aa": "Pro", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 199, "end_pos": 201 }, { "start_pos": 234, "end_pos": 236 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 28, "end_pos": 30 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 332, "end_pos": 334 }, { "start_pos": 379, "end_pos": 381 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 585, "end_pos": 587 }, { "start_pos": 613, "end_pos": 615 }, { "start_pos": 616, "end_pos": 618 }, { "start_pos": 628, "end_pos": 630 }, { "start_pos": 631, "end_pos": 633 }, { "start_pos": 744, "end_pos": 746 }, { "start_pos": 87, "end_pos": 89 }, { "start_pos": 941, "end_pos": 943 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PP83-1", "uniprot_ac": "A0A8M9PP83", "uniprot_id": "A0A8M9PP83_DANRE", "mass": { "chemical_mass": 31027.0, "monoisotopic_mass": 31027.0 }, "refseq": { "ac": "XP_021323091", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323091" }, "gene_names": [ { "name": "LOC110438041", "type": "recommended", "evidence": [ { "id": "A0A8M9PP83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP83" } ] }, { "name": "LOC110438041", "type": "synonym", "evidence": [ { "id": "XP_021323091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323091" } ] } ], "protein_names": [ { "name": "MADF domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PP83", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP83/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021323091", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323091" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021333332.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021333332", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333332" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PP96", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP96" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-63p21.2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP96", "locus": {} } ], "crossref": [ { "id": "A0A8M9PP96", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PP96", "database": "AlphaFoldDB", "categories": [] }, { "id": "101886613", "url": "https://www.ncbi.nlm.nih.gov/gene/101886613", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015425", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015425", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101886613", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886613", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PP96", "url": "https://www.orthodb.org/?gene=A0A8M9PP96", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45920", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45920", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45920:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45920:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021333332", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333332", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PP96", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PP96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G2T4", "url": "https://www.uniprot.org/uniprotkb/A0AC58G2T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G2T4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G2T4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPAECFLLNSSWTSLISHTPLLRLNALDFSDLWDDEDLELDSIDGDSTHNSPSQTTASPMVPPPPPLAPPVSLASESPWSSRTLRLHWRALLSLQPLPRVGRFGPQSIWATLEPVHLDTNRLEYLFESKNNSALCSLTAGRQQKQSCVCVLGVKRSNIITIALSRLPPAHLLPPAIHSMDNTVLDREDIQRLQTLIPTEDELNLIKEAKARAPCSALGSAEQCLLTLGDVPHLRARLQLWAFTLDHDTLEREIAEPLFHLKLAMEQLATNQTFRCILATVLAVGNFLNGCKAKGFELSYLCKLSEVRDTHGRQPLLHHVCVLLLQMYPQSSDLYSDITAVTKASKCDYTQVQLNLCQLEVLCKASWDQLRLLEKDGKKRKGGGRKDGCVEEASSLHQQLHQFLKDCEERLKVLRAVYRRVINRFHSFLLFLGYSRSMVRETSAEAFCKTVSDFALEYRATRSAILQQREKEKEKEKGRKKDSQSTPEFKIKLQQSPSDENQEQVKLEEVLKTPDSSSSSSFHFDFTLPRQRSKSSDKKGFHSSRRLKW", "length": 549, "header": "tr|A0A8M9PP96-1|A0A8M9PP96_DANRE Isoform 1 of FH1/FH2 domain-containing protein 1 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-63p21.2 PE=4 SV=2 CANONICAL=A0A8M9PP96-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PP96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP96/entry#A0A8M9PP96-1", "sequence": { "sequence": 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"isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 131, "end_pos": 133 }, { "start_pos": 271, "end_pos": 273 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPC4-1", "uniprot_ac": "A0A8M9PPC4", "uniprot_id": "A0A8M9PPC4_DANRE", "mass": { "chemical_mass": 95144.0, "monoisotopic_mass": 95144.0 }, "refseq": { "ac": "XP_021328883", "name": "bromo adjacent homology domain-containing 1 protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328883" }, "gene_names": [ { "name": "bahd1", "type": "recommended", "evidence": [ { "id": "A0A8M9PPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4" } ] }, { "name": "bahd1", "type": "synonym", "evidence": [ { "id": "XP_021328883", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328883" } ] } ], "protein_names": [ { "name": "Bromo adjacent homology domain-containing 1 protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4/entry#names_and_taxonomy" } ] }, { "name": "bromo adjacent homology domain-containing 1 protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021328883", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328883" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021328883.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328883", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328883" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "bahd1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120411-42", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120411-42", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PPC4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PPC4", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000086789", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000086789", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04714", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04714", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "564712", "url": "https://www.ncbi.nlm.nih.gov/gene/564712", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053032", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053032", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564712", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564712", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GRMENEM", "url": "https://omabrowser.org/oma/group/GRMENEM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PPC4", "url": "https://www.orthodb.org/?gene=A0A8M9PPC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46576", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46576", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46576:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46576:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01426", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01426", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021328883", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328883", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q6S0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q6S0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q6S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q6S0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120411-42", "url": "https://zfin.org/ZDB-GENE-120411-42", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSITAQVFFLAVVNTASHSSVAASGVSSLTVLQPRYLLVRTFGFAWQSVMTHARQRNSLCGYKSESADQVNCRITMDRTWPEKKAKRCSTQRGKAKEVKGKSAERDRKLYPLRGRHGLGEVSALNCCVVLTRLDESETCRNGMKAQVKEMQGKSKICKCRKKACKSCKAAEPKSKVKPDKSALYTEFILEPRQRRLASLNAEAVNSLLLDRVDPQQTSKPSKKQQQTKGDPSLSKDTAKDNDCPRKSQDNRKRGCTGETEQNRNPKKAKTESDTIDLQTLNSPAPKRLAGLNAAALLKLTSTSSAGKRRGKTEGKPSAGGVRGKQLLSKSRKQQHNLACQSTLKVSQQCCSFCEKHALHNEALWDGSTGSHGFISPGYQCRSMLGFPLKPVKEEKTETDVKSYYCCSQERSVEYCHRLALFLGQKPFPETDEHSLKGFLPSPHTLTHSAMPIGAHPYPCYPGYYVHIAHHGTPSLPVSSNQGSHPPSSVPPLKMCSSGVQRPKLLPSTVSHPTGIPHPAYCNSVGTCYGEACRLSSYAYRPTQPITSRGCSYNAGCSSCMHKMETEDYSYPLDDRSSSITMPSALPLSICPISSVPPPTQSVPHLQTPLPDTGRSQVQIRVGRECPQRAKPPSGSRSGVRDSAVCPHIKDGQLGSGHGSGAAKQSKISRRRATNGWLPVGVATEKEVFIVAEDSASLRRCYEGVQRDGEVIRVRDTVLLRSGPRKKSLPYVAKVSAFWDDPESGELMMSLFWYYRPEHTQGGRIPSMHCENEIFASRHQDENSVACIEDKCYVLTLAQYCRFCALVKCREEGFPKRSPLVPPSSYVIPAHRCVPNDIDPDLVFVCRHVYDFRYGRLLKNLQ", "length": 861, "header": "tr|A0A8M9PPC4-1|A0A8M9PPC4_DANRE Isoform 1 of Bromo adjacent homology domain-containing 1 protein isoform X1 OS=Danio rerio OX=7955 GN=bahd1 PE=4 SV=2 CANONICAL=A0A8M9PPC4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PPC4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4/entry#A0A8M9PPC4-1", "sequence": { "sequence": "MSITAQVFFLAVVNTASHSSVAASGVSSLTVLQPRYLLVRTFGFAWQSVMTHARQRNSLCGYKSESADQVNCRITMDRTWPEKKAKRCSTQRGKAKEVKGKSAERDRKLYPLRGRHGLGEVSALNCCVVLTRLDESETCRNGMKAQVKEMQGKSKICKCRKKACKSCKAAEPKSKVKPDKSALYTEFILEPRQRRLASLNAEAVNSLLLDRVDPQQTSKPSKKQQQTKGDPSLSKDTAKDNDCPRKSQDNRKRGCTGETEQNRNPKKAKTESDTIDLQTLNSPAPKRLAGLNAAALLKLTSTSSAGKRRGKTEGKPSAGGVRGKQLLSKSRKQQHNLACQSTLKVSQQCCSFCEKHALHNEALWDGSTGSHGFISPGYQCRSMLGFPLKPVKEEKTETDVKSYYCCSQERSVEYCHRLALFLGQKPFPETDEHSLKGFLPSPHTLTHSAMPIGAHPYPCYPGYYVHIAHHGTPSLPVSSNQGSHPPSSVPPLKMCSSGVQRPKLLPSTVSHPTGIPHPAYCNSVGTCYGEACRLSSYAYRPTQPITSRGCSYNAGCSSCMHKMETEDYSYPLDDRSSSITMPSALPLSICPISSVPPPTQSVPHLQTPLPDTGRSQVQIRVGRECPQRAKPPSGSRSGVRDSAVCPHIKDGQLGSGHGSGAAKQSKISRRRATNGWLPVGVATEKEVFIVAEDSASLRRCYEGVQRDGEVIRVRDTVLLRSGPRKKSLPYVAKVSAFWDDPESGELMMSLFWYYRPEHTQGGRIPSMHCENEIFASRHQDENSVACIEDKCYVLTLAQYCRFCALVKCREEGFPKRSPLVPPSSYVIPAHRCVPNDIDPDLVFVCRHVYDFRYGRLLKNLQ", "length": 861, "header": "tr|A0A8M9PPC4-1|A0A8M9PPC4_DANRE Isoform 1 of Bromo adjacent homology domain-containing 1 protein isoform X1 OS=Danio rerio OX=7955 GN=bahd1 PE=4 SV=2 CANONICAL=A0A8M9PPC4-1" }, "locus": {} }, { "isoform_ac": "A0A8M9Q6S0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4/entry#A0A8M9Q6S0-1", "sequence": { "sequence": "MTHARQRNSLCGYKSESADQVNCRITMDRTWPEKKAKRCSTQRGKAKEVKGKSAERDRKLYPLRGRHGLGEVSALNCCVVLTRLDESETCRNGMKAQVKEMQGKSKICKCRKKACKSCKAAEPKSKVKPDKSALYTEFILEPRQRRLASLNAEAVNSLLLDRVDPQQTSKPSKKQQQTKGDPSLSKDTAKDNDCPRKSQDNRKRGCTGETEQNRNPKKAKTESDTIDLQTLNSPAPKRLAGLNAAALLKLTSTSSAGKRRGKTEGKPSAGGVRGKQLLSKSRKQQHNLACQSTLKVSQQCCSFCEKHALHNEALWDGSTGSHGFISPGYQCRSMLGFPLKPVKEEKTETDVKSYYCCSQERSVEYCHRLALFLGQKPFPETDEHSLKGFLPSPHTLTHSAMPIGAHPYPCYPGYYVHIAHHGTPSLPVSSNQGSHPPSSVPPLKMCSSGVQRPKLLPSTVSHPTGIPHPAYCNSVGTCYGEACRLSSYAYRPTQPITSRGCSYNAGCSSCMHKMETEDYSYPLDDRSSSITMPSALPLSICPISSVPPPTQSVPHLQTPLPDTGRSQVQIRVGRECPQRAKPPSGSRSGVRDSAVCPHIKDGQLGSGHGSGAAKQSKISRRRATNGWLPVGVATEKEVFIVAEDSASLRRCYEGVQRDGEVIRVRDTVLLRSGPRKKSLPYVAKVSAFWDDPESGELMMSLFWYYRPEHTQGGRIPSMHCENEIFASRHQDENSVACIEDKCYVLTLAQYCRFCALVKCREEGFPKRSPLVPPSSYVIPAHRCVPNDIDPDLVFVCRHVYDFRYGRLLKNLQ", "length": 812, "header": "tr|A0A8M9Q6S0-1|A0A8M9Q6S0_DANRE Computationally mapped isoform of Bromo adjacent homology domain-containing 1 protein isoform X2 OS=Danio rerio OX=7955 GN=bahd1 PE=4 SV=1 CANONICAL=A0A8M9PPC4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 599, "start_aa": "Thr", "end_pos": 599, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr599", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:564712", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564712", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZHT3-1", "protein_name": "Bromo adjacent homology domain containing 1", "gene_name": "Bahd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTHTRRKSLPMLSSGPTGRGEPLQMEDSNVEQGAEDVEPGMPESPGHLTGRRKNYPLRKRSLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKAPSPTPSSEDAGLVQPRKRRLASLNAEALNNLLLEREDTSSLAGARRSRGGDPHRSRDRATGSWSFSKKRPRLGDLGEGSRDLSPELAPDEGARRDGDPAPKRLASLNAAAFLKLSQERELPLRPSRAQAEADGRSTEPLAPKVLRPKVNGKNCPKVRQGAGSGEATGPPNWQEQPEERWPSAPPRGPPIQPSHQAPGKALENPLRPNLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPAPQLAPLPMPGNPADYSGPCGGPELTALGGFYLYCGQDGLQCGSYSPCPMLPEGKLSPVAAPNEGLLMAPSSVPSGVPFQHPPWSASRYCSSEDTGANGYSICGVLPLSLTHIGTTCGGCPYKMPFTAGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPIPHLQTPISEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTVRSKAARRPSHPKQPRAQRPRPRRRRRRRTNGWVPVGAACEKAVYVLDEPEPAIRKSYQAVERHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFCAMAKRRGEGLPSRKTALVPPSADYSTPPHRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ", "length": 771 }, "evidence": [ { "id": "RGD:1563127", "url": "https://alliancegenome.org/gene/RGD:1563127#orthology", "database": "AGR" }, { "id": "HGNC:29153", "url": "https://alliancegenome.org/gene/HGNC:29153#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120411-42", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120411-42#orthology", "database": "AGR" }, { "id": "MGI:2139371", "url": "https://alliancegenome.org/gene/MGI:2139371#orthology", "database": "AGR" }, { "id": "FB:FBgn0052529", "url": "https://alliancegenome.org/gene/FB:FBgn0052529#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q497V6-1", "protein_name": "Bromo adjacent homology domain-containing 1 protein", "gene_name": "Bahd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTHTRRKSLPMLSSGPTGRGEPLQMEDSNMEQGTEDVEPGMPESPGHLTGRRKNYPLRKRSLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPSPTSSSEDAGLVQPRKRRLASLNAEALNNLLLEREETSSLAGARRSRGGDPHRSRDRATGSWSFSKKRPRLGDLGEGSRDLSPELAPDEGARRDGDPAPKRLASLNAAAFLKLSQERELPLRPSRAQAEADGRSTEPLAPRILRPKVNGKNCPKARQGAGSGEATGPPNWQEQPDERWPSAPPHGPPTQPSHQAPGKALENPLRPNLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPAPQLSPLPMPGNPADYSGPCGGPELTALGSFYLYCGQDGLQCGAYSPCPMLPEGKLSPVAAPNEGLLMAPSSVPSGVPFQHPPWSAPRYCSSEDTGANGYSICGVLPLSLTHIGTTCGGCPYKMPFTAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPIPHLQTPISEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTVRSKAARRPSHPKQPRAQRPRPRRRRRRRTNGWVPVGAACEKAVYVLDEPEPAIRKSYQAVERHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFCAMAKRRGEGLPSRKTALVPPSADYSTPPHRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ", "length": 772 }, "evidence": [ { "id": "RGD:1563127", "url": "https://alliancegenome.org/gene/RGD:1563127#orthology", "database": "AGR" }, { "id": "HGNC:29153", "url": "https://alliancegenome.org/gene/HGNC:29153#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120411-42", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120411-42#orthology", "database": "AGR" }, { "id": "MGI:2139371", "url": "https://alliancegenome.org/gene/MGI:2139371#orthology", "database": "AGR" }, { "id": "FB:FBgn0052529", "url": "https://alliancegenome.org/gene/FB:FBgn0052529#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TBE0-1", "protein_name": "Bromo adjacent homology domain-containing 1 protein", "gene_name": "BAHD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTHTRRKSLPMLSSGLTGRREPLQMEDSNMEQGVEGVEPGMPESPGHLTGRRKNYPLRKRPLVPEKPKACKVLLTRLENVAGPRSADEADELPPDLPKPPSPAPSSEDPGLAQPRKRRLASLNAEALNNLLLEREDTSSLAGTRRSRAGDPHRSRDRDRATGGWSSSKKRPRLGDLGGGSRDLSPEPAPDEGPRRDGDPAPKRLASLNAAAFLKLSQERELPLRLPRAHAEVDGRSTEPPAPKAPRPKWPKVNGKNYPKAWQGASSGEAAGPPGWQGCPDEPWPSATPCGPSVQPSHQPLSKALESPLGLRPHLPLLMGGQAALKPEPGRPGEESPAPKQELHQPSFPTPQLSPLPMPGNPADYNGLCVGPELTALGSFYLYCGQEGLQCGGYSPCPMLPEGKLSPVAAPHEEGLLLAPSSVPSGTPFQHPPWGSSRYCSSEDTGVNGYSICGVLPLSVTHAGTTCGGCPYKMPFAAEGCRSLGQLEFPLPEAGHPASPAHPLLGCPVPSVPPAAEPVPHLQTPTSEPQTVARACPQSAKPPSGSKSGLRTGSSCRHTARSKAARRPSHPKQPRVQRPRPRRRRRRRTNGWVPVGAACEKAVYVLDEPEPAIRKSYQAVERHGETIRVRDTVLLKSGPRKTSTPYVAKISALWENPESGELMMSLLWYYRPEHLQGGRSPSMHEPLQNEVFASRHQDQNSVACIEEKCYVLTFAEYCRFCAMAKRRGEGLPSRKTALVPPSADYSTPPHRTVPEDTDPELVFLCRHVYDFRHGRILKNPQ", "length": 780 }, "evidence": [ { "id": "RGD:1563127", "url": "https://alliancegenome.org/gene/RGD:1563127#orthology", "database": "AGR" }, { "id": "HGNC:29153", "url": "https://alliancegenome.org/gene/HGNC:29153#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120411-42", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120411-42#orthology", "database": "AGR" }, { "id": "MGI:2139371", "url": "https://alliancegenome.org/gene/MGI:2139371#orthology", "database": "AGR" }, { "id": "FB:FBgn0052529", "url": "https://alliancegenome.org/gene/FB:FBgn0052529#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VWC0-1", "protein_name": "Histone gene-specific epigenetic repressor in late S phase, isoform I", "gene_name": "Hers", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVSKKRSNAAERVQRSTATAAAAAAAAAAAATASSTQGKKRPGKQTKASGGGGDEADDKKSASKTDSAAKKPAKDPTGSSGVSTATTEGGAGNGGGKQTTSTTTSSTSSTTAPSASASASASNSLKLSPEERHEDGKARAINKMLKSLDIKIHGFDNLLPSGEERLNDGVLKSSISENVKTKSRAAAVKVISSLNPGKMPPVKRVRPSPEPVREKVAEKPAEKVLDKEKPKAEQQITPPPAPEESPASKVPKKTVQQAKKAKVESSLVQATVLTTTSAATSAPSSASTSKHTSTKNPGKKSAHSEQMPKKELSKLAKMGKPKKEANLVKSTARLPDSNTESVQMELEEIVSTPTVTPTPSATPTATPTPTATPTLTPTPTATRTRTPTPTLTPTPTPTSTPSSTAIAAGQPAPPPPPPGGAPKQRPKVKYTKTSAGSKGRMQQALNQKAPAASWSGAKDIYDFKSGSEDEEPIKMVLPSLKELREFSDEDNKPLKLFERQAEKTKVQVQDEEEQPLVKKEEKPPSEKEVKVKSKEKEKEKEKDVDPLSNAQQSEPAAKHTTSTSTTSTTSITSVKKQAKRKIATPMPSSAGRKKKTVGKGKAAAAKEPPPSGSSAESSSSEDERKLSAYSGPKRHRMASLNALAKVQCLYENESRTAHELGLSKATQQPPRIRTLDGSDDDNHKDSPRHGDTDRDKGSVSPPHTSAAPPAAPIAPPKEAEPRRELRYVPGGRGVGKHWEFDSDSETEELQLQQTLPPVKKKKLPKKAPPKKVASSETDAKRKKKSVQVEESDDEEAKEKEKEKEKPKPPKQLPKKRKTAFTEELIGDYKGILARKRMASLNASAIVAATYEVERHLDKNLASDCSSFESYDELDTMPTTTSKVTSAAAIKTEVIHIKKEPKESKESLRERERERESERRRERDNELKDSTVGKMSSHSIIEESNDSKYSKETKETNTDTTITTTGYRDSAASTKDAKDCSRPTSSSVVIVQDTDVTITGVYVNASNGAAQEAYCKMQYRVQSSVTEERVLRPGSVEPPKSYTPLSALSSMLPPGASSGLSEAHSSPPLPVHAAPTGPHVLLPGEHLSAGMYHAPDLGLHTEHALPDHHGPPPPSYAAAAAAAAAAAAYHAHQLAPGGGGVLHMHHQHQYAAHAAHAHHYQQAAEYHGGPPPPPHHYGGPPPQGHYGPPPGAPVPVPVAVPNTVTVPPERCDVGSPPPSYRASAYPPPSSVGMPPPTLGGGSSAFCAPSPLHHHQHQHQQPGPGVGPPHHDPSGYYQPAGPLISPHVIAAPPPPAQVKKLQEEDGPVSAAGSPTQLQQQQAAAEAAAAAADQAAAQSQSQSQGQSHGHAHSHAHNPQQAQHPPQPQPYPAGAVAAAAAAAAAHQGVPYSRSMHAAQMHYSTGYPPNYYAPYPGEVMCYSPPTYPPYFSSKVYQPSHPAHPAAHPQGPPPPGAYRRYPYYQHAGPPPPHELYEQQPPPPPVSSGSVSGPAQQQPPTSSPASVGAAGAGTAGAPSGSQLVPAHQQQHQQQHLEHYPGPPSYYAGYSPGGGASAGQCYTRGLQGPYMEYPPQCPCPMPQSCPKNVHTGPHIGSNIISNIDQSSSCSSSMLLSATSNSNIGGGSSSSSSSSSSTTLPACSSATTTTTASALTTSRGPVKNVTPNNSNSSGHTSTNSCRSSNNSNNSSNSSCQTIEMTSWATAATNTTSTTATTATTGTQCQMLVKTELKGENPQVTKMQYEAHVMPPPTPPESYCASDEKLLDDQEQEAELELRLRLGLGLEKSHGGQQHIEAYDLTCSTPPPVTVPQAAAVPRKARIGKSMAREMVYAAQQQLLPEKQLKQPKEAAAKLEAEPEMPFVLKAEIKAETKIKIEHDGEAQASTHISQLPDLKPTIKTEPEQELEQEAASVPSVAKTEPQPEVEVEREQQEPPVDEEQQPTPGGSKQRFNLLALSSGNKKTKTNNSYKSLIKQAEPKSYLCPGRRFIRRHGRAPAKYVKRRQMILTQRQQQRMRLQRREQQQQRRQQREAAAEVVAGAVVTPSLAGNPIEQAGSEVSIVKDQAPNSSATPSASPKRARPRKQEIAALHLLEGLDTTLSRGYFSDPELNHSSRKQAPTAVGGLYAASSPLTTATDHRGKQTTAEKRSKSETKKPPSGESSESGLPCKKPRKEPAGKVKGKGKKTTAGAAATTIASTAETQTEAVNAITASNQETNNNEYQTADLQAQKFRECPAVTDAKVAGTATSTSTASQQQNQQHSDEQHQFLVPSQPATASATAALAATPPPSRQGQATHTKRTRSRCKFGNRKRQRHRPGGVSYELDVTQPPATKANVVPKWNNGWMWAGKAFQGAVFLNSDDPLVLRTCYPAMRHVEGDIIRIRDCVLLKANEDNELPYVAKVAHLWQNPEDGEMMMSLLWYYRPEHTDQGRQRNDCPDEVYASRHRDHNSVACVEDKCYVLTFSEYCRYRRRLRAAEEDVEDVSIVPRRPSIATAPGFPVRTVPEHTNPELVMFCRRAYEFRTRRLLKLPHKNGLVCSSS", "length": 2529 }, "evidence": [ { "id": "RGD:1563127", "url": "https://alliancegenome.org/gene/RGD:1563127#orthology", "database": "AGR" }, { "id": "HGNC:29153", "url": "https://alliancegenome.org/gene/HGNC:29153#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120411-42", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120411-42#orthology", "database": "AGR" }, { "id": "MGI:2139371", "url": "https://alliancegenome.org/gene/MGI:2139371#orthology", "database": "AGR" }, { "id": "FB:FBgn0052529", "url": "https://alliancegenome.org/gene/FB:FBgn0052529#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4" } ], "pmid": "" }, { "name": "transcription cis-regulatory region binding", "id": "GO:0000976", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000976", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4" } ], "pmid": "" }, { "name": "heterochromatin formation", "id": "GO:0031507", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031507", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "chromatin silencing complex", "id": "GO:0005677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005677", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPC4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PPC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPC4" }, { "id": "PS51038", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51038" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BAH", "eco_id": "ECO_0000259", "start_pos": 709, "end_pos": 860, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 599 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPI5-1", "uniprot_ac": "A0A8M9PPI5", "uniprot_id": "A0A8M9PPI5_DANRE", "mass": { "chemical_mass": 55514.0, "monoisotopic_mass": 55514.0 }, "refseq": { "ac": "XP_021328932", "name": "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328932" }, "gene_names": [ { "name": "mgat4c", "type": "recommended", "evidence": [ { "id": "A0A8M9PPI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPI5" } ] }, { "name": "mgat4c", "type": "synonym", "evidence": [ { "id": "XP_021328932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328932" } ] } ], "protein_names": [ { "name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "type": "synonym", "evidence": [ { "id": "A0A8M9PPI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPI5/entry#names_and_taxonomy" } ] }, { "name": "alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "type": "synonym", "evidence": [ { "id": "XP_021328932", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328932" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328932" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPI5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mgat4c", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPI5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-429", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-429", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100333333", "url": "https://www.ncbi.nlm.nih.gov/gene/100333333", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057279", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057279", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100333333", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333333", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PPI5", "url": "https://www.orthodb.org/?gene=A0A8M9PPI5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12062", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12062", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12062:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12062:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04666", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04666", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23524", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23524", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021328932", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328932", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPI5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPI5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-429", "url": "https://zfin.org/ZDB-GENE-091204-429", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRLVLKYLDKMRCFRKRSTIPFLVALITFLLFINLYIEDGYVLEEDKRQLRETSMHPLNSERYVHTFKDITNFSGTINVTYRYLAGTPLPRKKYLTIGLSSVKRKRGNYLLETIKSIFDQSSYEELKEIIVVVHLADFDLAWCESLVQEISRKFGHHIIAGRLLVIHAPEEYYPSLDGLKRNYNDPEDRVRFRSKQNVDYAFLLNFCTNLSDFYMMLEDDVRCSRNFLTALKKVVASREGSYWVMLEFSKLGYIGKLYHSRDLPRLAHFLLMFYQEMPCDWLLIHFRGLLAQKDAIRFKPSLFQHMGYYSSYKGAENKLKDDDFEEDSLDIPDNPPASLYTNINVFESYDAAKAYSSVDEYFWGKAPSTGDFYVIVFNKATKISKIKIITGTDDRQNDILHHGALEVGEKLIGTKKGRQCSSYITLGEFKNGNIEVHDVDHKIAFDIECVRIVVTANQKEWLIIRSISLWTTQGASQ", "length": 477, "header": "tr|A0A8M9PPI5-1|A0A8M9PPI5_DANRE Isoform 1 of Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C OS=Danio rerio OX=7955 GN=mgat4c PE=4 SV=1 CANONICAL=A0A8M9PPI5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PPI5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPI5/entry#A0A8M9PPI5-1", "sequence": { "sequence": "MRLVLKYLDKMRCFRKRSTIPFLVALITFLLFINLYIEDGYVLEEDKRQLRETSMHPLNSERYVHTFKDITNFSGTINVTYRYLAGTPLPRKKYLTIGLSSVKRKRGNYLLETIKSIFDQSSYEELKEIIVVVHLADFDLAWCESLVQEISRKFGHHIIAGRLLVIHAPEEYYPSLDGLKRNYNDPEDRVRFRSKQNVDYAFLLNFCTNLSDFYMMLEDDVRCSRNFLTALKKVVASREGSYWVMLEFSKLGYIGKLYHSRDLPRLAHFLLMFYQEMPCDWLLIHFRGLLAQKDAIRFKPSLFQHMGYYSSYKGAENKLKDDDFEEDSLDIPDNPPASLYTNINVFESYDAAKAYSSVDEYFWGKAPSTGDFYVIVFNKATKISKIKIITGTDDRQNDILHHGALEVGEKLIGTKKGRQCSSYITLGEFKNGNIEVHDVDHKIAFDIECVRIVVTANQKEWLIIRSISLWTTQGASQ", "length": 477, "header": "tr|A0A8M9PPI5-1|A0A8M9PPI5_DANRE Isoform 1 of Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C OS=Danio rerio OX=7955 GN=mgat4c PE=4 SV=1 CANONICAL=A0A8M9PPI5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100333333", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333333", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZEV3-1", "protein_name": "MGAT4 family, member C", "gene_name": "Mgat4c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFKFYQMKYIFQILDKMRCLRKRSTVSFLGVLVVFLLFMNVFIEDSYVLEGDKQLIRETSTHQLNSERYVHTFKDLSNFSGTINVTYRYLAATPLQRKRYLTIGLSSVKRKKGNYLLETIKSIFEQSSYEELKEISVVVHLADFNSSWRDAMVQDITQKFAHHIIAGRLMVIHAPEEYYPVLDGLKRNYNDPEDRVRFRSKQNVDYAFLLNFCANTSDYYVMLEDDVRCSRNFLTAIKKVIASLEGTYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLTHFRGLLAQKNVIRFKPSLFQHMGYYSSYKGTENKLKDDDFEEESFDIPDNPPASLYTNMNVFENYEASKAYSSVDEYFWGKPPSTGDTFVIVFENPIKIKKIKVNTGTEDRQNDILHHGALDVGEKLIFSKQIRQCETYLRLGEFKNGNFEMSDVNQKIPFDIHCMRICVTKTQKEWLIIRSISIWTS", "length": 478 }, "evidence": [ { "id": "HGNC:30871", "url": "https://alliancegenome.org/gene/HGNC:30871#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5U3T0-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "gene_name": "mgat4c", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRCHLKKWVVVAAGLSILTSLYVYMQRAQSGNLKGSVIWTWDRESWMEGIKSHYLHFNISINVLGGVLQPSKKYLTVGLSSVRREKGFYLHDTLQSIFSESSEEELDQMVVVVLLADFDLPWIQQTADKISREFAVQLSKGRLLVIHANKEHYPPLTGLKRNFNDAPDRVSFRSKQNVDYSFLLHFSSNLSQYYIMLEDDVGCSRNFLSSIQQHIRSMTDSKWVTLEFSKLGYIGKLYQSKDLPTLARFLYNFYQEMPCDFLLSHFRRLLMQDKVIRFRPSLFQHMGTYSSFRGTYNRLKDEDFVQELADNPPADVRTNIQVFQTYVPEKAYSQDVEYFWGVSPIGTESFFLVVFREAVRISRVQIHTGSDGKDELASADVELGRVLVTGEPAVDCSGFKTLGSLQHGQFNEEGVQKLLPDAVVCLRIRVTAAQPEWVIISRIQVWTVKEDKTI", "length": 454 }, "evidence": [ { "id": "HGNC:30871", "url": "https://alliancegenome.org/gene/HGNC:30871#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9D306-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "gene_name": "Mgat4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKFYQMKYIFQILDKMRCLRKRSTVSFLGVLVVFLLFMNLYIEDSYVLEGDKQLIRETSTHQLNSERYVHTFKDLSNFSGTINVTYRYLAATPLQRKRYLTIGLSSVKRKKGNYLLDTIKSIFEQSSYEELKEISVVVHLADFNSSWRDAMVQDITQKFAHHIIAGRLMVIHAPEEYYPVLDGLKRNYNDPEDRVRFRSKQNVDYAFLLNFCANTSDYYVMLEDDVRCSRNFLTAIKKVIASLEGTYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLTHFRGLLAQKNVIRFKPSLFQHMGYYSSYKGTENKLKDDDFEEESFDIPDNPPASFYTNMNVFENYEASKAYSSVDEYFWGKSPSMGDTFVIVFENPITIKKIKVNTGTEDRQNDILQHGALDVGEKLIFSKQIRQCDTYLRLGEFKNGYFEMSDVNQKIPFDIHCMRICVTKTQKEWLIIRSISIWTS", "length": 478 }, "evidence": [ { "id": "HGNC:30871", "url": "https://alliancegenome.org/gene/HGNC:30871#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UBM8-1", "protein_name": "Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C", "gene_name": "MGAT4C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFKFHQMKHIFEILDKMRCLRKRSTVSFLGVLVIFLLFMNLYIEDSYVLEGDKQLIRETSTHQLNSERYVHTFKDLSNFSGAINVTYRYLAATPLQRKRYLTIGLSSVKRKKGNYLLETIKSIFEQSSYEELKEISVVVHLADFNSSWRDAMVQDITQKFAHHIIAGRLMVIHAPEEYYPILDGLKRNYNDPEDRVKFRSKQNVDYAFLLNFCANTSDYYVMLEDDVRCSKNFLTAIKKVIASLEGTYWVTLEFSKLGYIGKLYHSHDLPRLAHFLLMFYQEMPCDWLLTHFRGLLAQKNVIRFKPSLFQHMGYYSSYKGTENKLKDDDFEEESFDIPDNPPASLYTNMNVFENYEASKAYSSVDEYFWGKPPSTGDVFVIVFENPIIIKKIKVNTGTEDRQNDILHHGALDVGENVMPSKQRRQCSTYLRLGEFKNGNFEMSGVNQKIPFDIHCMRIYVTKTQKEWLIIRSISIWTS", "length": 478 }, "evidence": [ { "id": "HGNC:30871", "url": "https://alliancegenome.org/gene/HGNC:30871#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-429", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-429#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VUH5-1", "protein_name": "2.4.1.145", "gene_name": "Mgat4b", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKVISIRWKTCLPGLIIVSYLVCALLYFGMDITKIEPVEPRVVKNKTKVPRMYAKTINHDGNWETIVTNPELKPRYRVGGGRTGVQFVIGVPTVLRPKKNYVLQTVDCLIRRMTPEQRDNCLIVIFVGETKLQFAKFIVRELRVNHSTHMQAGLIDVIAPPLNYYPNFSRLHITLNDDPQRVQWRTKQNLDYIYLMSYAKSRGLYYLQLEDDVMANVGFMDYIQKFAVLHGSFRIAQQIDWIVMSFSELGFIGKLFRTSVLSSFVAYLKLFYNDQPIDWLLQSFVTLQSCRWDSVSDPECQRDFESRLLRSSQSQFQHMGAQSSLADKQQYQKDAFFNHNFARQRLRHLRQPLNLIATHRNSLLKHNLDLVEGETFIWIYMPRMPKMMKYLITNQFKQTQLHIRNAKDTAHNLAEFNIELVKGSPTLVANSSSTRQCGFVMSHTVQSFAERDGKAELPYNYMYYYIKEEPEGLSWFRRFRWASNASSFHELRSTMVLLLLVFQFVNNL", "length": 508 }, "evidence": [ { "id": "HGNC:30871", "url": "https://alliancegenome.org/gene/HGNC:30871#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "acetylglucosaminyltransferase activity", "id": "GO:0008375", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008375", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPI5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPI5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PPI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPI5" }, { "id": "PF23524", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23524" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MGAT4 A/B/C C-terminal", "eco_id": "ECO_0000259", "start_pos": 337, "end_pos": 465, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PPI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPI5" }, { "id": "PF04666", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04666" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MGAT4 conserved region", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 324, "start_aa": "Ser", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 }, { "start_pos": 72, "end_pos": 74 }, { "start_pos": 78, "end_pos": 80 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPJ4-1", "uniprot_ac": "A0A8M9PPJ4", "uniprot_id": "A0A8M9PPJ4_DANRE", "mass": { "chemical_mass": 118437.0, "monoisotopic_mass": 118437.0 }, "refseq": { "ac": "XP_021333442", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333442" }, "gene_names": [ { "name": "LOC110439932", "type": "recommended", "evidence": [ { "id": "A0A8M9PPJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPJ4" } ] }, { "name": "LOC110439932", "type": "synonym", "evidence": [ { "id": "XP_021333442", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333442" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PPJ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPJ4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021333442", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333442" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021333442", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333442" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPJ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110439932", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPJ4", "locus": {} } ], "crossref": [ { "id": "A0A8M9PPJ4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PPJ4", "database": "AlphaFoldDB", "categories": [] }, { "id": "110439932", "url": "https://www.ncbi.nlm.nih.gov/gene/110439932", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:110439932", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110439932", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PPJ4", "url": "https://www.orthodb.org/?gene=A0A8M9PPJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_021333442", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333442", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PPJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSHHCFLRLLLVCLTHSVVGCFPGLSFGDIAGNEPKIKLQALEVFNIADSSIQKPIKGTLLNNLVQFNSKYQWPRVNSAPYSQKSDGNAKNPSFRLTEPKDPAYVMNYQNKILSSSRNNPVDLSSVKYNKGHDAKTSYAFQTVQQELNPFTGSQWSSSDTNLGLRLVKIEGPVDRMHAGNVYRSETFGYQPISKSEMHSGSQQPLRLNEPYLREDISVQPAHAERISSNYMSRSSNANHNMRFKSDANAMFDQSNQNGPRRVMPIIEDLSFLEANQQVHKSSPHVFSAGTAALSQTSLGNVRDSSLSKIPTVPRLIPLVAKRPNSNRGDLIFPLKKLVMFSSEPDQMKHSDSRRVTIPQANPQNSLEYGNTKSYTNSYTLKDIQLTSAQNGYQNIGQSYQDVEPIQTRHTQKYDEVASGLSVDIPSTTNGVLSYKQFLSDENNIRSQLSALSKPSMQGTYLTSQIQFPKNTVLFLERDKSVNLPDITNDSLMKTSQHSTRHRTDLNPSGQSITHSLFVKKFPVPSLVPGNTIKSAYSVSPSASGTYKDSAVSTDQNHPYYISPKKPYAFKGFVPTSLQKSKVHFEQKPITNSLLNMQYVAAHPSTIQEPLISDQFKKMLFQFEDFKTSQDKQPDPDLTDSFNNRLQLSFKEGGSNMKYDVQGQAEARSGTESSNNGAAFLQKHLKKAYKELPLEEVQSETSKRWTSALHNLSQMPKVGSSISRFVGSNAHFSTTKFSNNHENPKSEIIQPIYKTPLINKAVAVVHPIHMYKYKEPEAPLNSAKEILGNRNPAEVTQSDISENAMRSSPTSSVVIGKLVEVTEKGKGSGENSYFQNSYSAPFTQSTSYRSTHLKSHKVNRFSTIYRSTIKQFDPINETNIDFYAIDASQSSSPTSSFVIGRLINTFNNASTKTNPKASSTKTALNSFKPFRFSDIAGSASFTNAKLHSAAITPKEVADVTRVSNHSDSTVMAEIIDSSSVISTLKIEDDVQSPVSFSVSEFLPTAAIDISMESRSSFTEEYSPSQTNSQLNHSKVDTHSFYEGTLMPDITTTSVSVTSDVDWLFLNL", "length": 1066, "header": "tr|A0A8M9PPJ4-1|A0A8M9PPJ4_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC110439932 PE=4 SV=1 CANONICAL=A0A8M9PPJ4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PPJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPJ4/entry#A0A8M9PPJ4-1", "sequence": { "sequence": "MSHHCFLRLLLVCLTHSVVGCFPGLSFGDIAGNEPKIKLQALEVFNIADSSIQKPIKGTLLNNLVQFNSKYQWPRVNSAPYSQKSDGNAKNPSFRLTEPKDPAYVMNYQNKILSSSRNNPVDLSSVKYNKGHDAKTSYAFQTVQQELNPFTGSQWSSSDTNLGLRLVKIEGPVDRMHAGNVYRSETFGYQPISKSEMHSGSQQPLRLNEPYLREDISVQPAHAERISSNYMSRSSNANHNMRFKSDANAMFDQSNQNGPRRVMPIIEDLSFLEANQQVHKSSPHVFSAGTAALSQTSLGNVRDSSLSKIPTVPRLIPLVAKRPNSNRGDLIFPLKKLVMFSSEPDQMKHSDSRRVTIPQANPQNSLEYGNTKSYTNSYTLKDIQLTSAQNGYQNIGQSYQDVEPIQTRHTQKYDEVASGLSVDIPSTTNGVLSYKQFLSDENNIRSQLSALSKPSMQGTYLTSQIQFPKNTVLFLERDKSVNLPDITNDSLMKTSQHSTRHRTDLNPSGQSITHSLFVKKFPVPSLVPGNTIKSAYSVSPSASGTYKDSAVSTDQNHPYYISPKKPYAFKGFVPTSLQKSKVHFEQKPITNSLLNMQYVAAHPSTIQEPLISDQFKKMLFQFEDFKTSQDKQPDPDLTDSFNNRLQLSFKEGGSNMKYDVQGQAEARSGTESSNNGAAFLQKHLKKAYKELPLEEVQSETSKRWTSALHNLSQMPKVGSSISRFVGSNAHFSTTKFSNNHENPKSEIIQPIYKTPLINKAVAVVHPIHMYKYKEPEAPLNSAKEILGNRNPAEVTQSDISENAMRSSPTSSVVIGKLVEVTEKGKGSGENSYFQNSYSAPFTQSTSYRSTHLKSHKVNRFSTIYRSTIKQFDPINETNIDFYAIDASQSSSPTSSFVIGRLINTFNNASTKTNPKASSTKTALNSFKPFRFSDIAGSASFTNAKLHSAAITPKEVADVTRVSNHSDSTVMAEIIDSSSVISTLKIEDDVQSPVSFSVSEFLPTAAIDISMESRSSFTEEYSPSQTNSQLNHSKVDTHSFYEGTLMPDITTTSVSVTSDVDWLFLNL", "length": 1066, "header": "tr|A0A8M9PPJ4-1|A0A8M9PPJ4_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC110439932 PE=4 SV=1 CANONICAL=A0A8M9PPJ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110439932", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110439932", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1030, "end_pos": 1032, "annotation": "n_glycosylation_sequon" }, { "start_pos": 488, "end_pos": 490, "annotation": "n_glycosylation_sequon" }, { "start_pos": 710, "end_pos": 712, "annotation": "n_glycosylation_sequon" }, { "start_pos": 875, "end_pos": 877, "annotation": "n_glycosylation_sequon" }, { "start_pos": 907, "end_pos": 909, "annotation": "n_glycosylation_sequon" }, { "start_pos": 963, "end_pos": 965, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1030, "end_pos": 1032 }, { "start_pos": 488, "end_pos": 490 }, { "start_pos": 710, "end_pos": 712 }, { "start_pos": 875, "end_pos": 877 }, { "start_pos": 907, "end_pos": 909 }, { "start_pos": 963, "end_pos": 965 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPM0-1", "uniprot_ac": "A0A8M9PPM0", "uniprot_id": "A0A8M9PPM0_DANRE", "mass": { "chemical_mass": 93427.0, "monoisotopic_mass": 93427.0 }, "refseq": { "ac": "XP_001345668", "name": "extracellular calcium-sensing receptor isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001345668" }, "gene_names": [ { "name": "olfcg12", "type": "recommended", "evidence": [ { "id": "A0A8M9PPM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM0" } ] }, { "name": "olfcg12", "type": "synonym", "evidence": [ { "id": "XP_001345668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001345668" } ] } ], "protein_names": [ { "name": "Extracellular calcium-sensing receptor isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PPM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM0/entry#names_and_taxonomy" } ] }, { "name": "extracellular calcium-sensing receptor isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001345668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001345668" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001345668.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001345668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001345668" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPM0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "olfcg12", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd15283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100007121", "url": "https://www.ncbi.nlm.nih.gov/gene/100007121", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100007121", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100007121", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IMCKPEQ", "url": "https://omabrowser.org/oma/group/IMCKPEQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PPM0", "url": "https://www.orthodb.org/?gene=A0A8M9PPM0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061:SF528", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061:SF528", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001345668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001345668", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PPM0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HV80", "url": "https://www.uniprot.org/uniprotkb/A0AC58HV80", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HV80-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HV80-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HV97", "url": "https://www.uniprot.org/uniprotkb/A0AC58HV97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HV97-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HV97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050419-156", "url": "https://zfin.org/ZDB-GENE-050419-156", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSVFFCTLLIFFQLYAKAEKPICIMMGDPKYPLLSKEGDISIGAVFPVHSIETLPLFKFTQKPQLLSCSSVSIRDFRMAQIMAFAIEEINRNESLLPNVSLGYQIYDTCGSGLSLMGANMALMNVQEFASRGSCNGQSPVHAIIGETESSNTVILSRTTGPFKIPVISPSASCECLSNRKEYPYFFRTIASDYHQSRALAYIIKYFGWSWVGAVNSDNDYGNHGMAIFLSTAEKEGVCVEYSVKFQRTEPEKLKKVVDTIKKGTSKVIVAFLTEFEMKNLLEYLIIQNVTGLQVIGVEAWITANSMIKPNSFHVLGGSLGFAVKKLNIEGFEDYVTKAFWETAFPCSQTSQKENSQYKLICNIYRDLLVLKNDNKDVPEQRYASNVYKAVYAVAHSLHNILKCRENGACETDMKIQPQQVVEALRKVNFTIKMGDCVWFDSTGAVVAQYEVVNWQPDYNGSIQFKPVGYYDASLPPNQRFVINTENIIWAGGQLKKPRSVCSENCPPGTRKAVQKGRPVCCYDCIPCAEGEISNETDSNNCKQCPGEYWSNAEKNKCVLKAVEFLSFKELMGIVLVFFSLLGAGLTTLVAILFYSKKDTPIVKANNSELSFLLLFSLMLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSDVMKWFGPIQQRLSVLVITIVQVLICVLWLAVSPPLPYKNTKYFKEKIILECSLGSTIGFSAALGYIGLLAILCFILAFLARTLPDKFNEAKFITFSMIIFCAVWITFIPSYLSSPGKLTVAVEIFAILASSFGLLFCIFLPKCYIIMCKPEQNTKLHIIGKLNK", "length": 837, "header": "tr|A0A8M9PPM0-1|A0A8M9PPM0_DANRE Isoform 1 of Extracellular calcium-sensing receptor isoform X1 OS=Danio rerio OX=7955 GN=olfcg12 PE=3 SV=1 CANONICAL=A0A8M9PPM0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PPM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM0/entry#A0A8M9PPM0-1", "sequence": { "sequence": "MSVFFCTLLIFFQLYAKAEKPICIMMGDPKYPLLSKEGDISIGAVFPVHSIETLPLFKFTQKPQLLSCSSVSIRDFRMAQIMAFAIEEINRNESLLPNVSLGYQIYDTCGSGLSLMGANMALMNVQEFASRGSCNGQSPVHAIIGETESSNTVILSRTTGPFKIPVISPSASCECLSNRKEYPYFFRTIASDYHQSRALAYIIKYFGWSWVGAVNSDNDYGNHGMAIFLSTAEKEGVCVEYSVKFQRTEPEKLKKVVDTIKKGTSKVIVAFLTEFEMKNLLEYLIIQNVTGLQVIGVEAWITANSMIKPNSFHVLGGSLGFAVKKLNIEGFEDYVTKAFWETAFPCSQTSQKENSQYKLICNIYRDLLVLKNDNKDVPEQRYASNVYKAVYAVAHSLHNILKCRENGACETDMKIQPQQVVEALRKVNFTIKMGDCVWFDSTGAVVAQYEVVNWQPDYNGSIQFKPVGYYDASLPPNQRFVINTENIIWAGGQLKKPRSVCSENCPPGTRKAVQKGRPVCCYDCIPCAEGEISNETDSNNCKQCPGEYWSNAEKNKCVLKAVEFLSFKELMGIVLVFFSLLGAGLTTLVAILFYSKKDTPIVKANNSELSFLLLFSLMLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSDVMKWFGPIQQRLSVLVITIVQVLICVLWLAVSPPLPYKNTKYFKEKIILECSLGSTIGFSAALGYIGLLAILCFILAFLARTLPDKFNEAKFITFSMIIFCAVWITFIPSYLSSPGKLTVAVEIFAILASSFGLLFCIFLPKCYIIMCKPEQNTKLHIIGKLNK", "length": 837, "header": "tr|A0A8M9PPM0-1|A0A8M9PPM0_DANRE Isoform 1 of Extracellular calcium-sensing receptor isoform X1 OS=Danio rerio OX=7955 GN=olfcg12 PE=3 SV=1 CANONICAL=A0A8M9PPM0-1" }, "locus": {} }, { "isoform_ac": "A0AC58HV80-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM0/entry#A0AC58HV80-1", "sequence": { "sequence": "MSVFFCTLLIFFQLYAKAEKPICIMMGDPKYPLLSKEGDISIGAVFPVHSIETLPLFKFTQKPQLLSCSSVSIRDFRMAQIMAFAIEEINRNESLLPNVSLGYQIYDTCGSGLSLMGANMALMNVQEFASRGSCNGQSPVHAIIGETESSNTVILSRTTGPFKIPVISPSASCECLSNRKEYPYFFRTIASDYHQSRALAYIIKYFGWSWVGAVNSDNDYGNHGMAIFLSTAEKEGVCVEYSVKFQRTEPEKLKKNVTGLQVIGVEAWITANSMIKPNSFHVLGGSLGFAVKKLNIEGFEDYVTKAFWETAFPCSQTSQKENSQYKLICNIYRDLLVLKNDNKDVPEQRYASNVYKAVYAVAHSLHNILKCRENGACETDMKIQPQQVVEALRKVNFTIKMGDCVWFDSTGAVVAQYEVVNWQPDYNGSIQFKPVGYYDASLPPNQRFVINTENIIWAGGQLKKPRSVCSENCPPGTRKAVQKGRPVCCYDCIPCAEGEISNETDSNNCKQCPGEYWSNAEKNKCVLKAVEFLSFKELMGIVLVFFSLLGAGLTTLVAILFYSKKDTPIVKANNSELSFLLLFSLMLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSDVMKWFGPIQQRLSVLVITIVQVLICVLWLAVSPPLPYKNTKYFKEKIILECSLGSTIGFSAALGYIGLLAILCFILAFLARTLPDKFNEAKFITFSMIIFCAVWITFIPSYLSSPGKLTVAVEIFAILASSFGLLFCIFLPKCYIIMCKPEQNTKLHIIGKLNK", "length": 805, "header": "tr|A0AC58HV80-1|A0AC58HV80_DANRE Computationally mapped isoform of Extracellular calcium-sensing receptor isoform X3 OS=Danio rerio OX=7955 GN=olfcg12 PE=3 SV=1 CANONICAL=A0A8M9PPM0-1" }, "locus": {} }, { "isoform_ac": "A0AC58HV97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM0/entry#A0AC58HV97-1", "sequence": { "sequence": "MSVFFCTLLIFFQLYAKAEKPICIMMGDPKYPLLSKEGDISIGAVFPVHSIETLPLFKFTQKPQLLSCSSVSIRDFRMAQIMAFAIEEINRNESLLPNVSLGYQIYDTCGSGLSLMGANMALMNVQEFASRGSCNGQSPVHAIIGETESSNTVILSRTTGPFKIPVISPSASCECLSNRKEYPYFFRTIASDYHQSRALAYIIKYFGWSWVGAVNSDNDYGNHGMAIFLSTAEKEGVCVEYSVKFQRTEPEKLKKVVDTIKKGTSKVIVAFLTEFEMKNLLEYLIIQNVTGLQVIGVEAWITANSMIKPNSFHVLGGSLGFAVKKLNIEGFEDYVTKAFWETAFPCSQTSQKENSQYKLICNIYRDLLVLKNDNKDVPEQRYASNVYKAVYAVAHSLHNILKCRENGACETDMKIQPQQVVEALRKVNFTIKMGDCVWFDSTGAVVAQYEVVNWQPDYNGSIQFKPVGYYDASLPPNQRFVINTENIIWAGGQLKPRSVCSENCPPGTRKAVQKGRPVCCYDCIPCAEGEISNETDSNNCKQCPGEYWSNAEKNKCVLKAVEFLSFKELMGIVLVFFSLLGAGLTTLVAILFYSKKDTPIVKANNSELSFLLLFSLMLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSDVMKWFGPIQQRLSVLVITIVQVLICVLWLAVSPPLPYKNTKYFKEKIILECSLGSTIGFSAALGYIGLLAILCFILAFLARTLPDKFNEAKFITFSMIIFCAVWITFIPSYLSSPGKLTVAVEIFAILASSFGLLFCIFLPKCYIIMCKPEQNTKLHIIGKLNK", "length": 836, "header": "tr|A0AC58HV97-1|A0AC58HV97_DANRE Computationally mapped isoform of Extracellular calcium-sensing receptor isoform X2 OS=Danio rerio OX=7955 GN=olfcg12 PE=3 SV=1 CANONICAL=A0A8M9PPM0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100007121", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100007121", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JYA5-1", "protein_name": "Vomeronasal 2 receptor, 16", "gene_name": "Vom2r16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHTLILFFLLLNIPLLVVSLIHPRCFWRMKQNEEKNGNLKTGCIFAFGVVKWPVEKEYYYNILSTQTNTENHQFSLALAFSMDEINKNPDLLPNKSLLFDFPFYSCKSHSELTTLIHGSVQQYDIFPNYVCNNETMCTLLLTGPNWKISVILRTYLDLYKSQQFLQLTYGPFHPVLSDNEQFPYLYQMAPKETSLALALVSFLIHFSWNWIGLAISDNDQGNQFLSYLRTEMGKYTVCFAFVNMIPVNMQLFMTRTDVYYNQIITSSTNVVIVYGDTDSTLALGFKMWKSLGVQRIWVTTSEWDVITSKRDFTFDTFHSIIAFQHHHGEISGFKNFVQTLNPFKYSDKYLVKLEWMYFNCEISASNCKTLKNCLYNESFEWLSEQTFDMAFSDGTHDIYNAAYAVAHALHEFFLQQGDNQQKYRGKWPNSVCLKLHSLLKKTHFTNPVGDRVIMNQREKMQEEYDIFYIWNFPQGLGLKVKIGEFSPYYSSGKQLWLFEDMIEWTTGNRQMPSSVCNSDCGPGFRKIWKEGMSTCCFDCIHCQENEISNETNVDQCVKCPEDQYANPEQNHCIHKALIFLTYQETLGMTLSLVALCLSTLTAAILGVFVKYHTTPIVKANNCRLTYILLITLIFCFLCPLLYIGHPNSVTCVLQQVTFGIVFTVAISTVLAKTITVILAFKVTAPQRMIKYFLISGVFNYIIPICTLIQVFVCTLWLGTSPPSVDFDPQSEHGHIIIVCNKGSVTAFYCMLGYLSCLALGSFTLAFLSRNLPGTFNEAKFLTFSMLVFCSVWITFLPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFIPKCYIILLRPERNSLQRIREK", "length": 849 }, "evidence": [ { "id": "RGD:1593384", "url": "https://alliancegenome.org/gene/RGD:1593384#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JYG8-1", "protein_name": "Vomeronasal 2 receptor, 12", "gene_name": "Vom2r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTLILSFLLLNIPLQVTGFIYPTCSWRIKENKDKSGNERIGCFFLIQAVQKPVEKEYFSHFFNTQKHTEIHKYSLVLAFSMIEVNRNPDLLPNMSLVFSFREIICGWQPELSIFIEVNLDDYGVLPNYTCKDDSLCGVVLTGLNWAPTLLLYTILNNFKSQQFPHLTYGHYHPVPSDHENFPYLYQMASDDTSLALALVSFIIHFSWNWIGLAFSDNDQGTHFLSYLKRGMEKNAVCLAFVSMIPVDMHLYMSRAEVYYSQILTSSANVVIIYGDTGSTLAVSFRMWESLGLQRLWITTTQLDVTPSMKENIYGLFAFGHHHGVISGFKNFVQTLNPVTYSNDNLAKLEWMHFNCEVSASKWKTLKNFSSNHSLEWLMENTFEMTFSEGSYNIYNAVYTVAHVLHKMTFQKFHNLPNAKGKVQNYVCNKLGAPLRKIHFTNPVGDRINMNREDKLQEEYDIFYIWNFPQGLAFKVKIGLFSPYFINGQQLHLSGDMIEWARGSTQMPTSVCSADCGPGFRKFRKKEMSACCFDCSPCPENEISNETNMEMCVLCPEDKYANTGQNDCIPKALIFLSYEDHLGMALSLMALGFSAFTAVVLGIFVKHHSTPIVKANNRTLTYILLLSLIFCFLCPLLFIGHPDSVTCILQQITFGVLFTVAISTVLAKTITVILAFKVTAPQRMMKYFLLSGVSMYIIPICTLIQVIVCAVCLGVSPPSVDIDAQSEHGHIIVVCNNGSVTCFYSVLGYLACLTFVSFTLAFLSRNLPGAFNEAKSITFSMLVVCSVWVTFLPVYHSTKGKIMVAVEIISILASSSGMLVCIFIPKCYIILFRPEKNSLKMIREKSPSHTHIS", "length": 853 }, "evidence": [ { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2JZT8-1", "protein_name": "Vomeronasal 2 receptor, 13", "gene_name": "Vom2r12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTLILSFLFLNIPFQVTGFIYPTCSWRIKENKDKSGNERIGCFFLIQAVQKPVEKEYFSHFFNTQKHTEIHKYSLVLAFSMIEVNRNPDLLPNMSLVFSFREIICGWQPELSIFIEVNLDDYGVLPNYTCKDESLCGVALTGVNWAPTLLLYTILNNFKSQQFPHLTYGHFHPVLSDHENFPYLYQMASDDTSLALALVSFIIHFRWNWIGLAISDNDQGTQFLSYLKRGMEKNAICLAFVSMIPVNMHLYMSRAEVYYSQIMTSSANVVIIYGDTGSTLAVSFRMWESLGLQRLWITTTQLDVTPSMKDNVYGLFAFGHHHGVISGFKNFVQTLNPVTYSNENLAKLEWMHFNCEVSASKWKTLKNFSSNHSLEWLMEHTFEMTFSEGSYNIYNAVYTVAHVLHEMTFQKFHNLPNAKGKVENYVCNKLGAPLRKIHFTNPVGDRINMNREDKLQEEYDIFYIWNFPQGLAFKVKIGLFSPYFINGQQLHLSGDMIEWARGSTQMPTSVCSADCGPGFRKFRKKEMSACCFDCSPCPENEISNETNMEMCVLCPEDKYANTGQNDCIPKALIFLSYEDHLGMALSLMALGFSAFTAVVLGIFVKHHSTPIVKANNRTLTYILLLSLIFCFLCPLLFIGHPDSVTCILQQITFGVLFTVAISTVLAKTITVILAFKVTAPQRMMKYFLLSGVSMYIIPICTLIQVIVCAVCLGVSPPSVDIDAQSEHGHIIVVCNNGSVTCFYSVLGYLACLTFVSFTLAFLSRNLPGAFNEAKSITFSMLVVCSVWVTFLPVYHSTKGKIMVAVEIISILASSSGMLVCIFIPKCYIILFRPEKNSLKMIREKSPSHTHIS", "length": 853 }, "evidence": [ { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KAL5-1", "protein_name": "Vomeronasal 2 receptor 19 like 1", "gene_name": "Vom2r19l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTMIFLFLLLNIPLLMVDFIHPRCFWRMKQNEDKDGNPGTGCTFFLQSVHWPVEKEYYSDIFNIQMHNENHKYALALAFAIYEINGNPDLLPNMSLIFEFTRDVCDWESQLNSVIQSSLKNHNILPNYICKEFTKCPMALTGLNWTTTLKLHTILNNFISQQFLQVTYGPFHPVLSDNEKFPYLYQMASDDKSLALALVSFIIHFGWNWVGLAISNNDQGIQFLSYLRREMEKGTVCFAFVNMIPVNMHLYMSRAEMYYNQIMTSSTNVVILYGDTDSTLAVSFRMWESLGIEKIWVTNSWWAATLSKKDHTFDNLYGTYAFGQHHGEISGFKNFVQTLNPAKYSDEHLVKLEWMYFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFTGGSYDIYNAVYSFAHALHEMTFQIFDNLPKDNGREHNYSCKKLCSFLRKTSFTNPVGDRVNMNQRHKQKEEYDIFYIWNFPQGLGIKVKIGMFSPYFPNGQQLHLSEDVLEWAKGSAQMPTSACSADCGPGFRKSWKDGMATCCFHCKPCPENEISNETNVDVCARCPDDQYANIEQNRCIPKAVVFLSYEEPLGMALSLISLGFSVFTIVLLGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSAICILQQITFGVVFTVSVSTVLAKTITVILAFKVTASQRMMKYFLVSRVPNYIIPTFTLFQVILCAVWLGASPPSIDIDAKSEHGHIIIACHKGSVTTFYCVLGYLGTLASGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKIMVAVEIFSTLASSAGMLGCIFVPKCYTVLFRQDQNSLVMIRMKSSSHAHIS", "length": 857 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0R4IS27-1", "protein_name": "Olfactory receptor CG6 precursor", "gene_name": "olfcg6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFLFYTILLFHLLHTKVENSLCRIMGDSNYPLFSKNGDVSIGGIFAIHRKETLPSFEFMQKPQPLSCSSVNLRDFRLAQTMIFAVEEINRSKSLLPNVSIGYKIYDTCGSRLSTMTAIMGLMNGQDFSTEDRCNGQSRLHAIIGESESSATIVLSRTTGPFRIPVISHSSSCECLSNKKDYPSFFRTISSDYHMSRALVYIVKHLDWSWVGAVNSDNDYGNNGMAIFLKAAHEEGICVEYSVKFYRTEPEKLKKVVDTINKGTAKVIVAFVSFVEMGLLIDQLSIQNITGIQMIGVEPWITANTYITSNSFRAMGGSLGFATKYIYIEGFAEYVMTPFWNTAFPCSESDRNHSHYELICSRYEDLLALKNDNKDVNEHRYSSNVYKAVYAVAHSLHGLLNCKEQEGCEKGLTIQPQQVVKALKNINFTIKSGDSVWFDNTGSVVALYEVVNWQKDSDGSFQFKSVGFYDAMMPPYKNLRLNTKNIVWAGGQLEKPRSVCSESCAPGTRKAAQKGRPVCCYDCIPCAEGEISNETDSINCKQCPGEYWSNTERNRCVIKAVEFLSFSEVMGIVLVIFSLFGAGLTVLVAVLFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTKWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPVQQRLSVFAFTLIQVLICVLWLTISPPFPYKNMKYYKEKIILECNLGNTIGFWAVLGYIGLLAALCFLLAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSFGLLVSIFAPKCFIILLKPEQNTKQHVMGKTTCSL", "length": 837 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A140T8U3-1", "protein_name": "Vomeronasal 2, receptor 130", "gene_name": "Vmn2r130", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLILLFLLLNIPLIVADFIYSRCFWRIKQNKDKDGNLGSGCALFIQAVQWPVEKEYFSPILNTQTYTENYKYILVFMFSINEVNRNSDLLPNMSLIFTFSALSCNESQLKSFIHLSLQDHDYFPNYICNDYICGVALVGLKWETTLTLYTILNNFMSHQFLFLNYGPFHPAMSDHEEFPYIYQMASEDTSLALAMVSFIIHFSWNWVGLAISDNDEGIQFLSHLRREMEKNTVCFAFVSMIPVNMHLYMTRTEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLDIKRIWVTTSQWDIITSKKDFTFNNLYGTFAFGHHHGEISGFKNFVQTLDLLKFSDEYLVKLEWMYFNCEDSAPKCKTLKNCSSNHPLEWLMVRTFDMAFTEGSYAIYNAVYAVAHALHELTFQKFDNLRPDNVKGQKYACNKLGSFLRKIHFTNPVGDRVNMNQRNKLQENYDIFYVWNFPQGLRLKVKIGIFSPYFINGQQLHLSEDMLEWARGSTQMLTSVCSADCGPGFRKFRRNGMPACCFDCRPCPENEISNETNVELCVPCPEDQYANTEQNNCIQRAVIFLTYKDPLGMALSLMALCFSAFTAVVLLVFVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCVLQQVTFGVAFTVAVPTVLAKTITIVLAFRVTAPQRMMKYFLVSGASIYIIPICTLIQVIVCAVWLGAAPPSVDIDARSEHGHIIIVCNKGSVSAFYCVLGYLACLAFGSFTLAFLSRNLPSTFNEAKSITFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSTLASGAGMLICIFVPKCYIILFMPDRNSLQMIRKKSSSHAHLS", "length": 855 }, "evidence": [ { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W422-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r54", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSASMWGYRVTQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQKEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSYQSLGKIEETVQKMQKCTAKVVLVFLSNLNFQLILRGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVSSLNAEETVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFVLALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQICLSPGTSTFVVLIASLIQVVLCGVWLATSPPFPDKDMISEPQHIVIQCQEGSGATFFCVLGYLGFLAGGTFSVAFLARGLPDIFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLKQGYCAQQEKQGEMLQRRYKFSGESPEPNI", "length": 878 }, "evidence": [ { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W4A7-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r53", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCTLLSVLFGCLSGSALSGPRVWIIPRQSPRFDRPGDVIVGGSFSIFHFSDGTLSNFTAPPPVLKTSSASMWSYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTCSHAVTQLVIHFQWSWVIILAHDDDFGQQASSLATQMLTPAGVCIEYHLHVPSHQSFGKIEETVQKMQKCTARVVLVFLSNSNFQLILHGLLAVPVSGQVWVSMDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSRIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHNLRNVYFKTSDGNKIMFDANGDLVTQFDIFQGKKTPAGVFHLVHVGLIDPQASSGNKMMVQLKQDLQVSSLNAEITVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTIFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQVCLSSGASTSVVLIASLIQVVLCGIWLITSPPFPDRDMISEPRHTVIQCHEGSGANFFCVLGFLGFLAGGTFSVAFLARGLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHQVQHNRQCEMLQRRCVSSGESLGSSL", "length": 878 }, "evidence": [ { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2WBA1-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r56", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLSCHWLSDPLAGMWLCTLLPVLFGCPSGSALSGARAWLLPRQSPHFDRPGDVIVGGSFSIFRFSNGTLSNFTAPPAGLQTSSVSMWGYRVAQSFVFAIEEINRSTHLLPNLTLGFSIRNSGDSAHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTSSHAVTQLIIHFQWSWVIILAHDDDFGQQASSLASQVLTPAGVCIEFYLYVPSHQSLGKIEETVRKMQKCTARVVLVFLSNYNFQLILYGLLAVPVSGQVWVSKDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCMWPYQNITVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHDMISYEHQDGKGTNSQDFQPWQLLHVLRKVHFKTPDGSEIMFDANGDLVTKFDIFQGQKTPDGVFHLVCVGLIDPQASSGNKMMVQKKMLKYQMKHAQVPTSVCSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCCIILLKPEKNTSSWLRQGHHV", "length": 865 }, "evidence": [ { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2WCY4-1", "protein_name": "Vomeronasal 2, receptor 16", "gene_name": "Vmn2r16", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLHAFTISFSLLKFSLILYSLTEPNCFWRIQSNEDNDGDLRSDCGFVLFTYEGPIEEKFYNNVIHFSGTMNNLDLIWNAQQSRNGGHTCDPDLEDGRSSLLIWMLKNSGHEKHRIPARRYEFLLVMYFATDEINRNPYLLPNMSLIFSLIVGMCEDTLGYIEEKYSPQKNRLNFINYNCGIPQTCNIQITGPSWTTSLKLAINSRRPKVFFGPFNPNLSDHDQFPYVHQVSTKDTHLSHAMVSLMLHFKWTWIGLVISDDEQGIQFLSGLREEMQTYAICLAFVNMIPETMQIYMTRADIYDKQIIESTAKVVIIYGEMNSTLEVSFRRWGYLGARRIWITTSQWDVITNEKDFSLDFFHGTITFAHHNGRIAKFNNFLQTMNTSKYPIDVTQTMQDWNYFNCSIFKNSVRKTGQFIFNNTLEWTTQHKIDMVLSEEGHNLYNAVYAVAHTYHELILQQVESQKMPKLKGVFSDCHQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFNIWNFPQGLGLKVKIGSYFPCFPQSQQLCISENMEWATGGALVPTSMCSVTCAAGFRKIHQKHTADCCFDCVLCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGSMTMCFSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLILCFLCSLFFIGQPNHATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTTPGRRMRGMLASGTPNLVIPICSLVQLVLCGIWLVTSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFVPKCFVILVRPDSNFLQKYKDKLFY", "length": 897 }, "evidence": [ { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3Q4EIC8-1", "protein_name": "Vomeronasal 2, receptor 129", "gene_name": "Vmn2r129", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLCAFTISLLFLKFSLILCCWSEPSCFWRIKNSDDNDGDLQRECHFYLGAADTPVEDNFYSSLLKFRIAASEYEFLLVMFFAIDEINRNPYLLPNITLMFSFIGGNCQDLLRVMDQAYTQINGHMNFVNYFCYLDDSCAIGLTGPSWKTSLKLAMHSSMPLVFFGPFNPNLRDHDRLPHVHQVAPKDTHLSHGMVSLMFHFRWTWIGMVISDDDQGIQFLSDLREESQRHGICLAFVNMIPENMQIYMTRATIYDQQIMTSSAKVVIIYGEMNSTLEVSFRRWEELGARRIWITTSQWDVITNKKDFTLNLFHGTITFAHHRVEIPKLNKFMQTMNTAKYPVDISHTILEWNYFNCSISKNSIRMHHITFNNTLEWTSLHNYDMAMSDEGYSLYNAVYAVAHTYHEYIFQQVESQKKAKPKRYFTACQQVSSLMKTRVFMNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYLPCFPQRQKLHISDDLEWAKGGTSPQVPSSVCSVACTAGFRKIYQKETADCCFDCVQCPENEISNETDMEQCVRCPDDKYANIEQTHCLSRAVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKHNDTPIVKANNRILSYILLISLVFCFLCSLLFIGPPDQVTCILQQTTFGVFFTVSVSTVLAKTITVVMAFKLTTPGRRMRGMMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKIVILCNKGSVIAFHVVLGYLGSLALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSTRGRVMVVVEVFSILASSAGLLMCIFVPKCYVILIRPDSNIIKKHKGKVLN", "length": 850 }, "evidence": [ { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I6AGG5-1", "protein_name": "Vomeronasal 2 receptor, 56", "gene_name": "Vom2r56", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADMEKAYTLIVFFLLLRLSFILCSFPEATCFWRINHNENLESNMRKDCGFILFTIPVHLVEDHFRVLLDFPLPVNTYPYVLVMLFAIEEINKNPNLLPNSTLGFTFLGDQCDITSTDLNNLNMLSKSGEMNPNYICEYSFCDVALTGPTWTVSARVGTLLQLFKIPQVMLSVTYGPFHDSLSDRDLFPHLYQIAPKDTSLVLAMVSLMIHFLWKWVGLVILDDDQGVQFLSDMKEEVKTNEICLAFVNMIPANMQLYIERAETYYFQIMTSSANVVIIYGNVNSTLEVSFRRWEMLGIWRLWITTSQWDVISRSRDFTIDSFHGTLSLSHHYQEISTFKHFIQKTNFSAYPEAVSLVRLGWIYLNCSVSVCECKTLNHCLSNTILELLPWHSFDMAMNDERYNIYNAVYAVAHAFHNMRLQQVDIKVLESWEGLIPRCMQVNDFLKNVRLINPIGDPVNINQGRNLDAMYDIFNVLNFPQGYVLKVKVGQFSPYFAHDQQLFLSEDMIEWATGSRQFSTSVCSMPCHPGFKKSHQEGKADCCFDCSRCPANEISNTTDSEECVKCPEDWYADTEQTHCLPKAVTFLAYEDPLGMALVCLALCFSVLTALVLGVFLKHRETPIVKANNRTLSYILLTALIFCFLCSLLFVGNPNTTTCILQQTTFGILFTVSVSTVLAKTLTVVLAFRITLPGRRMRGLMVSRIPKYIIPICTVVQIILYGIWLWTSPPFVDIDTHSEHGCITITCSKGSVMAFYCVLGYLGSLALVSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSSKGKVMVAVEVFSILASSMGLLGCIFIPKCYIILLRPDRNSIQKFRDKTQMNQ", "length": 861 }, "evidence": [ { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6AK91-1", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "LOC134484845", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSLMFHFGWTWIGLVISDDDQGIQFLSDLREEMQRHAICLAFVNMIPETMQTYKTRVKIYDQQIMTSSAKVVVIYGEMNSTLELSFRRWAYLGAQRIWITTSQWDVITHKKDFSLDFFHGTVTFAHHHNDIPVFRNFLQTINTSKYPIDISQSMLQWNHFNCSISKSNNKMDCFTFNNPLEWLAQHTFDMVLSEEGYNLYNAVYAVAHTYHELILQQIESPKMEEPKGVFTDCQQEVSLLKTRVFINPVGELVNMNHKENQCAKYDIFINWNFPQGLGLKVKIGSYFSCLPQSQQLHISEDWEWVTRETLVPSSVCSVTCIAGFRKIHQKQTANCCFDCVQCQENEIANDTDMEQCVRCPDDSYANLEQTKCLQRAVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYRDTPIVKANNRILSYILLISLAFCFLCSLLFIGHPNQATCILQQTTFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRKMMIKGATNLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKVIIICNKGSVTAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTKGKVMVVVEVFSILASSAGLLGCIFVQKCYVLLVRPDLNVLRK", "length": 646 }, "evidence": [ { "id": "RGD:6500225", "url": "https://alliancegenome.org/gene/RGD:6500225#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GK53-1", "protein_name": "Vomeronasal 2 receptor, 33", "gene_name": "Vom2r33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLCTFLFVLLGCLPGSALSEPRSWILPRQSPHFDRPGDVMVGGSFSIFCFSDGTLSNFTAPPTGLQASRVSMWGYRVAQSFVFAIEEINKSTQLLPNLTLGFSIQNSGDSVHGALYETMGFLTGQEEPIPNYTCCHGSPQAALVGDTRSSLSLPMARLLGLYKFSQISYSSSLPSLSDKIQFPSFLRTLPSDLTSCHAVTQLIIRFQWSWLIILSQDDDFGEQASSLATQQLSAAGVCIEFHLDVPSQHSLGKIEETVQKMQKCTARVVLVFLSNSNFQLILSGLLAASVSGQVWVSNDTLHIAMALSIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLHPSQIPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQVCSGNESLKNKPYPFPEVSKIDAAYTAVYSIAHALHDMVACEHQDGIDTNPQDFHPWQLLHVLKKVHFRTPDGSEIMFDANGDLVTKFDILQGQKTLNGVFHLVHVGMIDPQASSGNIMMIQLKEDLQVSSMNAEITVPTSICSERCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALMAILLAGLALLVLGVFLKHRDTPVVRVNNRTLSYFLLISLSLCSLCSLLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTVTVVLAFRVTKSGSRIQVCLSPGASTSVVLIASLIQVVLCGVWLATSPPFPERDMISEPQHIVIQCQEGSGATFFCVLGFLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHCAHQDRQCSLFH", "length": 864 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GKI6-1", "protein_name": "Vomeronasal 2 receptor, 71", "gene_name": "Vom2r71", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKMCAFTISSLLLKFSLILCSFTEPSCFWRIQNNEDNDGDLRSDCGFVLITYEGPIEENFYNNVINFRIPARRYEVFLVLLFATDEINRNPYLLPNMSFMFSRIVGMCEDTLGSLERKYTPQSNSWKFINYNCGIQEVCDVQLTGPSWTTSLKLAINSRNPKVFFGPFNPNLSDHDQFPYVYQVATEDTCLSHAMVSLMLHFRWTWIGLVITDDDQGIQLLTDLREEMERHGMCLAFVNMIPETMQIYMTKAKIYDNQIMTSSAKVVIIYGEMNSTLEVSFRRWAYLAAQRIWITTSQWDVITTRKDFSLDFFHGTFTFAHHNVELPKFRHFMQTMNTSKYPVDISQSMLGWNYFNCSISKNSISKIDHFTLNNTLEWLAQHKFDMFLSEEGYNLYNAVYAVAHTYHELILQVESQKMAEPKGLFTDCQQVALLLKTRAFTTPVGELVNMNHRENQCAKYDISIAWNFPQGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTLIPTSMCSVACIAGFRKIHQKQVTHCCFDCAHCPENEVSNETADMEQCVRCPDDKYANLEQTYCLQRVVSFLAYEDPLGMALGCTALCFSTLTVLILFTFLKYKDTPIVKANNCLLSYILLISLIFCFLCSLLFIGHPNHITCILQQTTFGVFFTVAISTVLAKTITVVMAFKISTPGNRMKGMLTSGAPNLVIPICTLIQLVLCGIWLGTSPPFIDRDIQSEPGKTIVICNKGSIFAFHFTLGYLDSLTLMSFAVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTKGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRTDSNFLQKYKDKFHY", "length": 849 }, "evidence": [ { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GL30-1", "protein_name": "Vomeronasal 2 receptor, 3", "gene_name": "Vom2r6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTIAFFPLKFCLILCSLTEPNCFWRIKKIEVYDGDLQNDCGFVLFTLESPIEENFYNHIINFRIPARKYEFFLVMFFATDEINKNPYLLSNMSLIFSFIFGMCEDTMGVLDKAYLHQNNYFDLLNYNCGRKKRCDVKLTGPSWKTSLKLSVNSRAPKIFFGPFNPNLSDHDQFPYIYQIATKDTYLLHGMVSLMFHFEWTWIGLVITDDDQGIQFHSDLREEMQRHAICLAFVIMIPESIKLYNTKFKIYDQQLMTSSAKVTIIYGKMISTLGLSFRRWAYLVARRIWITTSKLDDITYDKDFSLDFFHGTVIFVHHHNDIATFRNFMQTINTSKYPVDISQSMGQWNHFNCSISKNKKKMDFFMLKNPLEWLKQHTFDMVLSEEGYNLYNAVYAVAHTYHELIFQQVESQEMAKPKGLFTDCQKVASLLKTRVFTNPVGELVNMNHKENQCAKYDIFIIWNFPKGLGLKVKIGSYFPCLQQSQHLHISEDWEWVTGETLVPSSVCSETCTAGFRKSHQKQTADCCFDCVQCQENEIANDTDMEQCVRCPDDSYANLEQTECLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYRDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQATFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRKMMIKGATNLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKVIIICNKGSVTAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVIVEVFSILASSAGLLGCIFVQKCYVLLVRPDLNVLQK", "length": 841 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N5X2-1", "protein_name": "Olfactory receptor CW1 precursor", "gene_name": "olfcw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTPVLRAIHLVFFLFYPIQSNSEANCKLWKELDLTVVHKEGDVILAGMFPIHSKGIDQELNFRNQPDQRKCWGFNMRVFRWSQAMIFFIEEINRNPTLLPNITLGYRLYDTCGLIALSLRTALSVVSQPMKRSSSEMCSSPSIPIIIGDSGSTLSMAISRLLNLFHIPLVSYFASCACLSNKHQFPYFFRTIPSDVNQANALARLVKHFGWTWVGTVGADDAYGRTGIDLFTAAVTQLGVCVSYRIIIPKLPTQQQLQDIVRTIRDSSAHVLVAFAIEEDIKPVVDEIVLQNVTGKQWVASEAWVTSTLISTKENFPSLSGTIGFAIRRAEIPGLKHFLDSIQPLADPYNVFAREFWETQFQCTLNTSLPTSSTMDPVNYSHSCTGMERMQDTQSIFNDVSQLRVTYNMYKAVYTVAHALHNLLLCQREHRSALTQQCPDIHNLQPWQVIEVLRKVNYTNMFGDLIYFDENGDPVGSYDIVNWQKGGDDVPVQYITVGRFDSSLPKGQQLVLNQNKIVWHGGTNKVPVSVCSASCPPGYRKVRLEGQPVCCYDCMLCAEGSISNTTDQAECLLCPEDFWSNKHRNYCVPKEIEFLSYLEAFGMVLAAIAILGAVAAISVGVVFFRHRDTPLVRANNSELSFLLLISLTLCFICALTFLGQPSHWACPLRRISFGLTFALCLSCLLSKTLVVLIAFKSTLPGNNTARWFRPPQQRLGVFICSLLQGGVCIAWLTTASPYPVKNTWLYRDRIILECHLGSVVYFCCVLGYIGCLAAFCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSYGVLLCIFAPKCYIIIFMPEKNSKKYLMTQK", "length": 866 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PU52-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWISLNIFLYLSLNCIFAASVVNPGTCQLQGHFKLNGMYQDGDFILGGLFEVHFFTLFPKLSFKSEPEPPYCEKFDMESFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCVMLGMAFRAAISLASGTEEYFSNLNCTGPPPVIGVVGDPGSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVRILSHFGWTWVGLIYSDDDYGIYASVSFQQEMQQFGSCISFSEILPHDNNPKDIQRIMEVIKASTASVVVVFSTSSYLMPLIDEVVLQNLTGRQWIASEAWATSPVFHTPRYLPFLGGTLGIAIRRGEILGLQEFLLHIHASNNPKDNMLKIFWENMFRCSFETRSKDTIGEQEKSICTGHEDLSTTKTPYTDVSGLRASYNVYKAVYALAHALHDLMECEEGRGPFDGNSCGNITNLKPWQLVHYLQKVNFKTGFGDHVSFDENGDALAIYDVLNWHPSSDGSIRLHTVGVVNEGAGTGKVLSLDESALYWNFQTKNPPRSVCSASCPPGTRQAMRKGLPICCFDCLPCGDGEISNATDSTECVTCPDEFWSNFDKNQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHLNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGTMKWFGAAQQRCTVLVLTALQVVICAVWLSNASPTPIKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKKAIIRRETKKR", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q146-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYQDGDFILGGLFEVHFFTVFPDLTFTTNPKSPYCEIFNMEGFQHAQTMAFAIEEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLTSGTEESFLNLNCSGPSPVIGIVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSNRKKYPSFFRTIPSDAFQVRAIVQVLKHFKWTWVGLLYSDDDYGVYAAQSFQQEMRQFGLCAAFSEFLPHDNNPRTIQHIMGVIQGSTAKAVVVFAPSSFLIPLMNEVVLQNMTGRQWIASEAWATSLESHIPSFQPFLRGTIGIAIRRGEIQRLHDFLLRIRPSNDPKNYMLRIFWENMFGCSFGKGDTEGEQVIKVCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHALHDLMECEEGKGPFSKNSCADKTNLKPWQVVHYLQNVNFTTGFGDYVSFDKNGDALAIYDVLNWQPSSDESIRIYTVGVVKEGTETGMVLTLDEDAIFWNFETRKPPRSVCSESCPPGTRRATRKGLPVCCFDCLPCGDGEISNTTNAVECFLCPDEFWSNQYNNHCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVIFVFALHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHVVFGISFVLCMSSILVKTMVVIAVFKSSRPEGKGAIKWFGAVQQRSTVVVLTVLQVLICAVWLSTASPTPYKNNQYIRSKIVYECAIGSVVGFSMLLSYIGFLAAASFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFVPAYVSSPGKYTVAVEIFAILASTFGLLIAIFAPKCYIILLHPERNTKNVIMGRETQNK", "length": 829 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q166-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWSPLIICLYLSYNFKSAASILMGSCQLQGHFGLNGMYQAGDVILGGLFEVHLLAVFPELSFRSAPEPPYCEQFDMASFQQAQTMVFAIDEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLVSGTEELFSNLNCTGSPPVIGIVGDSNSTPSIAISSVLGLFRVPIVSYFATCSCLSNRKQYPSFFRTIPSDAFQVRAMVNILKHFGWTWVGLIYSDDDYGNYAAQSFLQDIQIYGGCVAFTEILPLNNNRKYIEHVVGVIQASTARVVVVFSTSTYVLPLMDEVVLQNVTNRQWIASEAWATSPMFHTQRLLPFLGGTLGIAIRRGEIQGLHEFLLHLRPKNDQHNNMVRIFWEKMFGCRFNPGGKGDKQCSGQEDLSSIDTAYTDVKELRASYNVYKTVYALAHALHDLTECDEERGPFSENRCADITNLQPWQLVHYLQKVNFTTGFGDHVSFDKNGDVLAIYDVMNWHPSSDGSISVRTVGVVNEGAASGKVLTLDEDAIYWNFKIKKAPQSVCSESCPPGTRQATKKGLPVCCFDCLPCGDGEISNVTNAIECTVCPDEFWSNKDKDQCVPKEVEFLSYEDPLGISLTTACLLGTCFCALVMIIFCQHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGSMKWFGTTQQRCTVLILTALQVVICIVWLSNSSPAPHKNSQHISSKIVYECAIGSLAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVTSPGKYAVAVEIFAILASSFGLLGAIFAPKCYIILLHPEKNTKKAIMGRQITK", "length": 860 }, "evidence": [ { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q1C5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNAHLLFTVKMLCIARLCIAVCGVDLGTCILQGDAQPPALSEDGDFIVGGAFTIHYYVRTEKYTYTRRPQPLECSGSMDFRELRFARALQFAIQEINNSSDLLPGIFLGYHIYDSCGSVPMAIKVALQLANGLDPKYNDTDSCAKSAAVLALVGDSASTPAISISRIFGPFEIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEKEGICVEYSEAYYRTYPLSKLKRVADVIRRSTARVIVAFVAAGDMRFLLEELSKEPLPPMQWIGSEAWVSDPQMLRFNLSIGTMGVAVPRSLIPGFRKFLLDLSPYKVLKFPLLTEFWESSFSCSLQQQTDPSTGMPACDGTEDLGRLKNPYTDTSQLRVSNMVYKATYAIAHALHGIVCNETQCSKNIKVKPRQVFDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPEGQEFSLNKAIIWYDGSEKVPVSVCSENCPPGTRKAVKKGRPVCCYDCIPCGEGEISNKTDSPDCDKCPPDYWPSTEKDKCLPKPVEFLSWDEILGIILAVLSVSGSLLALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWVVLGYIGLLASLCFVLAFLARKLPDNFNEAKFITFSMLIFSAVWITFIPAYVSSPGKFTVAVEIFAILASSFSLILCIFAPKFFIILFRPEENTKKHLMGKVQSKSY", "length": 856 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "RGD:11359049", "url": "https://alliancegenome.org/gene/RGD:11359049#orthology", "database": "AGR" }, { "id": "RGD:1597414", "url": "https://alliancegenome.org/gene/RGD:1597414#orthology", "database": "AGR" }, { "id": "RGD:6500225", "url": "https://alliancegenome.org/gene/RGD:6500225#orthology", "database": "AGR" }, { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "RGD:11482623", "url": "https://alliancegenome.org/gene/RGD:11482623#orthology", "database": "AGR" }, { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "RGD:1593384", "url": "https://alliancegenome.org/gene/RGD:1593384#orthology", "database": "AGR" }, { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1596944", "url": "https://alliancegenome.org/gene/RGD:1596944#orthology", "database": "AGR" }, { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RHU5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCCYICVTLIASTGTCQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMTSFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTSRQWIASEAWVTAAVFRTPYFQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTTNTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEGSIKLHNIGVVNEVATGMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTSRAMRKGFPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDRCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AUZ8-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcv3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHSLETMTILLLWLLVYHLSVLNPAQASKCLLQNEFEPGLMANGDFVIGGIFPLHYNQEMPDLNFTYKPGPVKCNGFDTRAFRWAITMKLAVEEINKRVDLLPNYTLGYKIFDSCAYPLTGQRSAVAVLNGPNELESPLCADAAPLLAVIGESGSAQSIVVSRILQPFGIPMISYFSSCACLSDRREFPTFFRVIPSDAYQVKAIAKLLRHFNWTWIGVIRGDHEYGRFALQGLLKELEGTGICVAYQKMIPLLYDRQKALEIIHVMSHSTARVVVVFSAEGELTPFLRDYMEQNVTGIQWIASEAWVTSSVFAGSEFDPFLGGTIGFGIRQGQIPRLKEYLTTVNPERYPTNPLVYELWGALYGCSPSWSNLSSHLPSCTGKETVRLQYSAYLNTSSPRISYNVYKAAYAIAYSLHNLIYCTPGKGPFSNSTCANAPHIYPWQLQQYLQEVSFTISGEKVNFDMKGDSIPSYDLINWQRGSAGNIEFINVGMFDGALESGQELVIKEEAIMWPGHQTEVLVSVCSNSCAPGFRKAVRRGQPLCCFDCVPCDSGKISNETDSLDCIACSEDYWSNADGTVCIPKVVEFLSHDAMGLTLTVIAVAGACLTLAVFSVFLYYKNTPVVRINNSELSFFILLSLTLCFLCALIFIGEPTSWSCMLRHTAFSITFSLCISCILGKTLVVLAAFTATRPGNNLMKWLGPTQQRIIIFCCTLIQVLICTVWLVASPPFPYRNTKYQQSKIILDCSVGSDLAFWCVLGYIGLLACVCFFLAFLARKLPGNFNEAKYITFSMIIFCAVWLAFVPAYVSSPGKFTTAVEIFAILASSFGLLLCLFTPKVYIILVKPEKNTKQHLMGKDK", "length": 859 }, "evidence": [ { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AV03-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYNNVLLIVTLQCIITRLYVVYGNRLGSCILQGDPQPPVLFDEGDFIIGGAFSIHYYLRTEKHTYTMRPQSLECSGSMDFRELRFARVLQFAIQEINNSSDLLPGITLGYRIYDSCGSVPMAVKLSFQLANGLDLIFNDNDSCSKSAAVAALVGESGSTPSISISRLYGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEEEGICVEYSEAYYRTQPRSKLMRVADVIRRSTARVIVAFMASGDMRLLLEELSQQPLPPMQWIGSEAWFTDPEMLRFNMCIGGVGFAIPRSVIPGFRTFLLDLSPQRAMKFPLLTEFWESSFSCSLKQQTGPSTGMPACDGTEDLGRLKNPYTDTSQLRISNMVYKATYAIAHALHGIICNEKKCNKNIKIEPREVLDKLKQVKFSKNNYSVSFDAYGDPVAVYELVNWQLQKDGSIDFVTVGKYDSSQPKGKEFSLSRAIIWYDGTEEVPVSVCSESCPPGTRKAVQKGRPVCCYDCINCADGEISNDTDCLDCHECLSDYWPNNEKNKCLRKPVEFLSWDEILGIILAAFSVAGSLVALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPSQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFGLILCIFAPKFFIIIFRPERNTKKHIMGKVPSKAL", "length": 856 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "RGD:11359049", "url": "https://alliancegenome.org/gene/RGD:11359049#orthology", "database": "AGR" }, { "id": "RGD:1597414", "url": "https://alliancegenome.org/gene/RGD:1597414#orthology", "database": "AGR" }, { "id": "RGD:6500225", "url": "https://alliancegenome.org/gene/RGD:6500225#orthology", "database": "AGR" }, { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "RGD:11482623", "url": "https://alliancegenome.org/gene/RGD:11482623#orthology", "database": "AGR" }, { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "RGD:1593384", "url": "https://alliancegenome.org/gene/RGD:1593384#orthology", "database": "AGR" }, { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1596944", "url": "https://alliancegenome.org/gene/RGD:1596944#orthology", "database": "AGR" }, { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B2Z8-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcg8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLFLYSVLSLYHLNTKAENTLCQMIGNPKYPLLSKDGDITIGALFVIHSEVSLPSFAFTQKPNLLSCSSLNIKDFRLAQTMIFAIEEINKNTNLLPNISVGYQIYDTCGSRFHSMSATMALMNGPKNSEGYTCNEQSSVHAIVGETESSNTIILSRTTGPFKIPVISPTATCECLSNRKEFPSFFRTIASDYHQSRALAYIVKHFGWTWVGAVNSDNDYGNNGMATFQKTAKEVQICVEYSVKFIRTETEKIRNVVNVIKKGTAKVIVAFLTGFEMKSLLEQLSSQNITGLQMIGVEAWITSKTLITSKSFHVLGGSLGFAVRKIQIEGFADYVMKAFWDTAFQSFSNADLNYSQYQDLLLVKNYNEDVLEQRFVSYVYKAVYALAHSLHSLLRCTEQGGCGKALTIQPHQLVEALRKVNFTVKMGDQVWFDSTGGVIAQYDVVNWQQNSDGSVQFQSVGYYDASLSPDQRFMLNTEKIVWAGGQLEKPRSVCSESCPPGTRKASQKGRPVCCHDCIPCADGEISNETDSNNCKQCPGEYWSNANKNKCVTKAVEFLSFTEVMGIILVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSIPFIGRPTQWSCMLRHTAFGITFVLCISCILGKTIVVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTLIQGLICVIWLTKSPPFPYKNMKYFQEQIILECSVGSTIGFWAVLGYIGLLAVLCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKLTVAVEIFAILASSFGLLFCIFAPKCYIILLQPEQNTKQQMMAKTPSKI", "length": 832 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "RGD:11359049", "url": "https://alliancegenome.org/gene/RGD:11359049#orthology", "database": "AGR" }, { "id": "RGD:1597414", "url": "https://alliancegenome.org/gene/RGD:1597414#orthology", "database": "AGR" }, { "id": "RGD:6500225", "url": "https://alliancegenome.org/gene/RGD:6500225#orthology", "database": "AGR" }, { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "RGD:1593384", "url": "https://alliancegenome.org/gene/RGD:1593384#orthology", "database": "AGR" }, { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1596944", "url": "https://alliancegenome.org/gene/RGD:1596944#orthology", "database": "AGR" }, { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PAH3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTKKSELLLLMVLVTHGICVPNLAQVCRLLGQPALPLLSEERNINIGAIFSLHKSALLKSHNFTSKPKQTTCGGLNLREFKFVQTLIFAIEEINNSSLLPGASLGYKIYDSCGSVAQAIFSGMALMNGYEETLSDTSCSTPPAVHAIVGESNSSPTIGLASVVGPFSLPLVSHFATCSCLSNRKRFRTFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGIATFEEAAKQEGICIEYSEAVFKTDPEVQFLKTIEVIKKATTKVVVAFMAFGDFVLLLKVMAQQNITGIQWIGSESWITSRNLAETKEYHFLSGAVGFAIANSKPVGLREFLMNVHPDKELNNELLKEFWETVFLCSFRNSSSGGCTGSEKLSELQNEYTDFSELRIENKVYTAVYAVAHSLHNVLKGFKFFTNSSKKQLPTPQKVLEYLRDVNFTVNTNENIFFDASGDPVARYDLVNWQPTKDGSLQFKLVGIYDSSLPSEQRLQINQESMLWAGNSGQLPVSVCSESCPPGTRKAVQKGRPICCYDCIPCAEGEISNYTDSSDCFPCGLEYWSNESKDRCVLKVIEFLSYTEIMGVGLCIFSFIGVLLTATVSFLFYFYKETPIVRANNSELSFLLLFSLTLCFLCSLTFIGRPTDWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLIQVIICVLWLTMSPPFPFLNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFFARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSAPGKYTVAVQLFAILASSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKS", "length": 849 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PD42-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWITLCIYLYLSLNYICAHSILRTSDSCRLQRRFHLNGMYKDGDVILGGLFQVHFFTVFPEQSFRTEPEPPFCEKFDMESFQQAQTMAFAIEEINKNPNLLPNITLGFHLYDNCVRLGMAFRAAISLASGTEESFQNLNCTGPPPVIGIVGDPSSTPSIAISSLLGLFRVPIVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLIYSDDDYGVYAAQSFHLEMQMFGHCVAFSEILPHNNNQRDIQRIMGVIQASTARVVVVFSTSSFLLPLIDEVASQNMTGRQWIASEAWATSPVYHSPRLLPFLGGTLGIAVRHGEIPGLHDFLLHLGPGNESRNNMLRIFWENMFGCSFEPGVKDTNSEIKLCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHGLHDLMQCEKGRGPFRGESCADITNLKPWQLVHYLQKVNFTTGFGDHVSFDENGDALAIYDVLNWQPSSDGSIQIFTVGVVKERTETGMVLTIDEDAIYWNFETKKSPQSVCSESCSPGTRRATRKGLPVCCFDCLPCRDGEISNTTDAIECMLCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGSCFCVLVMIIFGLHRNTPIVRANNSELSFMLLLSLKMCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGAMKWFGAAQQRCTVLVLTVLQVVICSVWLSTASPTPYKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKNAIMGRETQKR", "length": 867 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PFV7-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcg9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLYLCTLLLFFKLKVSVGNASCKIMGEPKYPLLFKDGDVTIGALFPVHSIETAPSFEFTQKPQLLSCSSVNLRDFRLAQILIFAIEEINRSESLLPKLSLGYKIYDTCSSKLSSMSATMALMNSFEFAGRDKCNGQTSVHAIIGETESSATVILTRTTGPFKIPVISHAASCECLSSRKEYPSFFRTISSDYHQGRALAYIVKHLGWSWVGAVNSDNDYGNYGMAIFLNTAHKEGICVEYSEKFYRTEPEKLKKVVDTIKKSTAKVIVAFISFLEMRLLVEQLSAENITGLQIVGVEGWTTSKSLITPKTLNVLRGSLGFAMRKIYIEGFAEYVLKPFWDTAFPCIPNQRNDSWVILNCSRYQDLLVLKNYIEDVPEHRFSINVYNAVYAVAHALHSLFKCKEQEGCEKDLLTQPQQVVDALKKVNFTVKMGDRVWFDSTGATLAQYEVVNWQQNSDGSVNFKKVGYYDASLPPDQRFVLNIKEILWAGGNLKKPRSVCSESCPPGTRKAAQKGRPICCYDCIPCADGEISNDTDSNNCKQCQGEYWSNADKNKCVQKSVEFLSFTEVMGIVLVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTQWSCMLRHTAFGITFVLCISCVLGKTLLVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTFIQVLICVLWLSISPPFPHKNMKYYEEKIILECSLGSTIGFWAILGYIGLLAALCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSISLLLCIFAPKCYIILLKPEQNTKQYMLGKTTSKFY", "length": 839 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "RGD:11359049", "url": "https://alliancegenome.org/gene/RGD:11359049#orthology", "database": "AGR" }, { "id": "RGD:1597414", "url": "https://alliancegenome.org/gene/RGD:1597414#orthology", "database": "AGR" }, { "id": "RGD:6500225", "url": "https://alliancegenome.org/gene/RGD:6500225#orthology", "database": "AGR" }, { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "RGD:11482623", "url": "https://alliancegenome.org/gene/RGD:11482623#orthology", "database": "AGR" }, { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "RGD:1593384", "url": "https://alliancegenome.org/gene/RGD:1593384#orthology", "database": "AGR" }, { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1596944", "url": "https://alliancegenome.org/gene/RGD:1596944#orthology", "database": "AGR" }, { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2U8-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLCEMWITLNICLYMYFNHISGVFTSESCQLQGCFKLNGMYQDGEFIIGGLFEVQNLKVFPELSFTNEPELPQCEEFYMASFQQALTMVFAINEINSNSKLLPNITLGYQIYDNCLRLGVAFRAAMSLVSGTEESSNLSCTGPPPVIGIVGDPGSTQSITISSVLGLYRVPMVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLLYSNDDYGIYAAQSFQQEMQILGGCVAFSEMLPYDNNGRDIQRIAGVIQKSTAKVVVAFSTDLASLMDELLLQNVTGKQWIASEAWTTTPVLQTPQYLPLLGGTLGIAIRRGQIQGLYEFLKNLRPDKNPKNSTIRIFWETMFGCKFEVGGKKVDEQQERGRNKCSGQEDLNNSETAYTDVSELRASYNVYKAVYALAHALHDLVKCEEGKGPFTGNSCADISNLKPWQLVHYIQNVKFTTGFGDHVSFDENGDALAIYDVMNWHPRSDGSIIVHVVGVYEEAILGKVLTLDEDALFWNFETKKPPDSVCSESCPPGTRRARKKGLPVCCFDCLPCGDGEISNTTDSPECFICPEDFWSSPENDRCVPKEMEFLSYDDPLGISLTTASLLGTCFCVLVLVIFAYHHNTPVVRANNSELSFLLLVSLKFCFLCVLLFIGRPRLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKTSRPEGKTSIKWFGSAQQRGTVIALTSAQVAICTVWLSSASPTPHKNNQYIHSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFMARKLPDNFNEAKFITFSMLIFCAVWIAFVPAYASSPGKYAVAVEIFAILASSFGLLAAIFAPKCYIIILHPERNTKKAIMGRSTQNK", "length": 868 }, "evidence": [ { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2V5-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcx2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALLCATLLMVWFLMYLSVQSQYNSKVRCVFQGDDDTNTFYQGGDVVLGGLFPLHFSPISSLSSYKTKPTPTTYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPDKDSGQSCEDTRKQPSPVVVGEASSGISMAVLRSLGCFKIPLVSYFASCSCLSNKKEFPAFMRTMPSDLFQIKALAKLVHYFQWTWVGVIGVDTDYARFAIQLFLKESQQLNICLAYVQLYPVALNQDSAEELVRMLKSSSATVIISFSVDSYLYGILKECRRQNVTHLQWIASEAWATSKSLWEEFGDLLKGTLGFAIHRADIPHLGSYLKEIRPQTSHFLSEFWEETFRCRLNGSLNTHAHGEQAQNWPACNGSESLDDVYTTYSDVSQLRVSYNVYKAVYLIAHALHDMSTCVPGKGPFQNGTCGSLFQIQPWQLLYYMKQTNFTTLGEEIRFDENGDPIASYDLMNWQRGSDSSLQLVRVGFYDASLEDDKDLVIDESLIMWHRAEKAPESLCSKSCLPGSRKARQKGKPVCCFDCISCAEGEISNHTDSIECLTCSEDTWPNQSQDQCIPKTLEFLSFQEPLGIILWVFSAFGACAALAVLCVFVMYRKTPVVRGNNIELSFLLLLFLCACFLIGLTFLGKPTDWLCQIRYPAFGISFTLCISCILAKTVVVLMAFRATIPGNNVMKWFGPVKQRSSVILCTCVQALICIIWLTTKPPLASYNSKFMSETIIVECSVGSEIGFWCVLGYVGLLACLCFLMAFLARKLPDNFNEAKFITFSMLIFFAVWITFIPVYLSSSGKYMVAVHVFAILASAFGLLLCIFFPKCYIVLLKPEKNDKKHIMKK", "length": 863 }, "evidence": [ { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T5D2-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCYYICVTLMASTGICQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMESFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLHNLTSRQWIASEAWVTAAVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTANTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEESIKLHNIGVVNEVATEMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTRRAMRKGLPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDQCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSLAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6G6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAILLFCLFLSCNFICVTLMVSSGTCQKQGHFTLNGMHQDGDFVIGGLFEIQSYVKVYPEISFRTQPKLPNCDLFYMTSFQQALTMVFAISEINNNPNLLPNITLGYQIYDNCLRLGVAFRAATALISGTEETISDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRLPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAMVQTMRHFGWTWVGLIYSNNDYGIYAAQSFHKEMQLFGHCVAFSEILPQDNNPRVIDHIIGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTGRQWIASEAWVTSTVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETEDKETFGQQIKKVCTGQEDLSITNTPYTDVSGLRAPYNVYKAVYALAHALHDLMQCKEKRGPLSEKNCADITDLKPWQLLSYLKKVNFTTGFGDPVSFDNNGDALAIYDVLNWQPSSEGSIKLHSIGVVNDEVATGMVLRLNKDEIYWNFEAQKAPRSVCSESCPPGTRKAMRKGFPVCCFDCLTCGDGEISNTTDAIKCTVCPDEFWSNFNKDQCVPKEIEFLSYEDPLGISLTTASLLGTCFCALVMIIFAFHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFNSSRPEGKGAMQWFGAAQQRCTVLVLTVLQVVICAVWLSTSSPTPHKNNQYVRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRETKKY", "length": 869 }, "evidence": [ { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6Z6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcq17", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLYLSLCLCFKHIYADSIHRLRSCQLQGRFKLNGMYQDGDFILGGLFHVHFFTVFPELSFRMEPQQPYCEKFNMEGLQHAQTMAFAINEINKNPTLLPNITLGYHLYDNCVMLRMAFRAAMSLASGTEDSYSNLNCTGPPPVIGIVGDASSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKHFKWTWVGLLYSGDDYGVYAAQMFHKEMQLSGHCVAFSEILPNDHNPKDIQRIIRVIQGSTARVVVVFALSSFLIPLMDEVVLQNMTGCQWIASEAWATSLEYHTPRFLPFLGGTLGIAIRRGEIEGLHEFLLRIRPSNDTSQNIVRIFWENLFGCRFETGGLKTGREQEKMECTGQEDLSTTNTPYTDVSGLRASYNVYKAVYALAHGLHDLMQCEEGRGPFIGNSCADITSLKPWQLVHYLQNVNFTTGFGDHVTFDKNGDALAIYDVLNWQPSSDGSITVHKIGVVYEGATTGMMLTLDADAIYWNFETKKPPLSVCSESCPPGTRQATRKGLPLCCFDCLPCGDGEFSNTRDAVECMMCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGAMKWFGASQQRCTVLVLTALQVVICAVWLSTASPTPHKNNHYFRSIIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFALLLAIFAPKCYIILLHPERNTKNAIMGRETQNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TDV0-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfck1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRISLGWVVCLVKEMHVNLLLILTLLCIRRLFPAVCGVHLGTCILQGDPQPPSLFSKGDFVIGGTFTIHYYLRTEKRTYTVRPQPLMCSGSMDFRELRFARVLQFAIQEINNSSNLLPGITLGYHIYDSCASVPMVIKVAVQLANGLQLAFNDTDSCAQSSEVLALVGESGSTAAITTSRLFGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEVEGICVEYSEAYYRTQTRNKLQRVADVIRRSTARVIVAFMAAGDMRFLLEELSQQPPPPMQWIGSEAWVTDPQMLRFNLSIGAVGFAIPRSVIPGFRKFLLDLSSEQALKIPVLKEFWESSFGCSLKQHTGYFSGMPACDGTEDLGTLKNPYTDTSQLRISNMVYKATYAIAHALHGIVCNGKLCDKNIKVEPRKVSDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPKGQEFSLNRAIIWYDGTEKVPVSVCSESCPPGTRKAVKKGRPVCCYDCINCADGEINNETDSLDCHKCQPDYWPNAEKIKCLPKPVEFLSWDEILGNTLAAFSIAGSLVALSMALVFYKNRVSPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFSLILLIFAPKCFVIVFRPEENTKRHLLGKVPPKAL", "length": 870 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "RGD:11359049", "url": "https://alliancegenome.org/gene/RGD:11359049#orthology", "database": "AGR" }, { "id": "RGD:1597414", "url": "https://alliancegenome.org/gene/RGD:1597414#orthology", "database": "AGR" }, { "id": "RGD:6500225", "url": "https://alliancegenome.org/gene/RGD:6500225#orthology", "database": "AGR" }, { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "RGD:11482623", "url": "https://alliancegenome.org/gene/RGD:11482623#orthology", "database": "AGR" }, { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "RGD:1593384", "url": "https://alliancegenome.org/gene/RGD:1593384#orthology", "database": "AGR" }, { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1596944", "url": "https://alliancegenome.org/gene/RGD:1596944#orthology", "database": "AGR" }, { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUY1-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWVILHIYFFISCNYMSVALMASSGTCQLQGHFTLNGMYQNGDFLIGGLFEIQYLKAFPGLSFRTEPKLPHCENFYMTSFQQAITMVFAINEINNNPNLLPNITLGYQMYDNCLRLGVAFRAATALISGTEETLSDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMIQILRHFEWTWVGLLYSDDDYGINAALSFHHDVQQFGGCVAFSEILPNDNNQMAVQHIVRVIQNSTAKVVVVFSTSSYLLPVIDEMLLKNITGRQWIASEAWSTSPVLLNPRLRYVLGGTLGIAIRRGEIEGLDNFLLRLRPDNFSQNSMMRIFWENMFECNFDTIGGLRTKLCSGQEDLRSKFTPYTDVSELRASYNVYKAVYALAHALHDLMHCEEGRGPFSENRCVDISNLKPWQLVHYLQRVKFTTGFGDHVSFDKNGDALAIYDVLNWQLSSEESVTVRRIGVVDEGVTTGKVFTLDENAIYWNFETNKPPRSVCSESCPPGTRQATRKGLPVCCFDCLPCGDGEISNTTDTTECIACPNDFWSNPEKDQCIPKEVEFLSYEDPLGISLTTAAMLGTFICALVMTIFAHYRNTPVVRSNNSELSFLLLLSLKLSFLCVLLFIGQPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKNAMKWFGAAQQRGTVLILTALQVLICAVWLSTASPTPHKNSRYIRSIIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDSFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIIILHPERNTKKAIMGKGTKNK", "length": 863 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UVL1-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLTWHRLFIKATPSKVFIINNIHRGELKRNVEMWIIAKICLYLSFSCISVASIFRSGPCQLQGQFRLNGMFQEGDLILGGLFEVHFLTVFPEQSFRTEPEPPYCEQFDMASFQQAQTMVFAIDEINRNPNLLPNITLGYYLYDNCVKLSVAFRAAMALVSGTEESFSSLNCTGPPPVIAIVGDPGSTHSIAISSILGLFRVPMVSYFATCSCLSDRKTYPSFFRTIPSDAFQVRAMVQILKRFGWTWVGLLYSDDDYGIYAAQSFQKEMQLFGACVGFSEMLPRDNNHEDIQSIVEVIQTSTARVVVVFSTEAYLLPLMDEVALKNVTGRQWIASEAWATSPVFHTQHLLPFLGGTLGIAIRRGEIQGLKEFLYYLHPDSNTRNNIVRIFWENIFGCSFEIGGRERKVCTGQEDLKSTNTAYTDVSGLRASYNAYKAVYALAHALHDLMQCEDGRGPFSGNKCADQINLQPWQVVHYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWQPSSDGAISVSTVGVVNEGASMKMVLTLKENSIFWNFKNRKPPQSVCSESCPPGTRQVRRKGLPVCCFDCLPCADGEISNTTDAIECKICPDELWPNPNKDQCVPKEEDFLSFEDPLGISLTTASLLGTCFCALVMVIFSHHRNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPKLWTCQLRHAAFGISFVLCVSSILVKTMVVIAVFKSSRPESKSAMKWFGVAQQRGTVMALTTLQIVICTVWLSMASPKPYKNSLYISSKVVYECDIGSVVGFSLLLGYIGLLAAVSFLFAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYMILFHPERNTKKSIMGRATQIK", "length": 894 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V5L1A2-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSVSMWGYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFSQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSHQSLGKIEETVQKMQKCTSKVVLVFLSNSNFQLILHGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVPSSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPSWLKQGHHI", "length": 845 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AB13A3P1-1", "protein_name": "Olfactory receptor CG7", "gene_name": "olfcg7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSANSLFMVSLTFRMILYFYTILFLRCFQAKTENAFCQIIGEAKYPLLSKDGDVTIGGIFAIHSKETLPSFEFQQKPQPLLCSSVNLRDFRLAQIMIFAIEEINKSENLLPNVSIGYRIFDTCGSRLSSMSATMGLMNELKFAAGETCNGQSPIHAIIGETESSATVILSRTTGPFKIPVISHSASCECLSNRNDYPSFFRTISSDYHQGRALAYIVKYLGWSWVGAVNSDNDYGNYGMAIFLETAQKEGICVEYSVKFYRTETEKLKRVVDTIKKSTAKVIVAFVSFIEMGLLIEQLSIQNITGFQIIGVEGWITSKNYITTNSFHSMGGSLGLALRKIHLEGFLDYVTKSFWSTAFPCSQTEGILPTVGCSKYKDLLPLKNYTEDVPEHRYSSHVYKAIYAVAHSLHSLLKCKEGEDCEKGHATQPQQVVEALKKVNFTVKFGDRVWFDRTGATVAHYEVVNWQQDTDGSFQFKQVGYYDASLPPDQRFVLNIESIIWPGGNLEKPRSVCSESCSPGTRKAAQKGRPVCCYDCVPCADGEISNETDSVNCKQCPREYWSNGEKNKCVLKAIEFLSFTEIMGIVLVCFSLFGVGLTAVVAILFWSKMDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMVFKATLPGSNVMKWFGPTQQRLSVLAFTFIQVLICVLWLTISPPFPNKNMTYYKEKIIIECSLGSTISFWAVLGYIGLLAVLCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSFGLLLCIFAPKCYIIICKPEQNTKQHVMGKTSLKVQ", "length": 851 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TCB3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNFGAGLRTGSRNGNEKWKRMTFCRSSAFCHMFSSTLYLISSMARHAVVLRAGACQLQGRFRLNGMYQDGDVILGGLFEAHFFTLFPELTFRTEPAPPYCEIFNMESFQYAQTMAFAINEINRNPSLLPNISLGYHLYDNCVMLGMALRAAMSLVSGIEESFLNLNCTGPPPIIGVVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMIQLISHFGWTWIGLLYSDDDYGTYAAQSFHQEMQLFGFCIAFSEPLRYDSNPRDIQRLMEVIQASTSTVVVVFSPSTLVIPLMNEVVLQNMTGRQWIASESWATSPVFYTPRFLPFLGGTLGIAIRRGEIEGLREFLLQLRPKNDPRNNMLKIFWENMFGCSFETGPHVKNVCTGQEDLSTTNTPYTDVSELRAANNVYKAVYALAHALHDLMKCEEGKGPFSKNSCAEISNLKPWQLVHYLQKVNFSTRFGDHVSFNKNGDALAIYDVMNWQPGSDRSIRIHTVGVVSEELEKGLMLTLDEDAIYWNFETKKPPQSVCSESCPRGSRRATRKGHPVCCFDCLPCRDGEISNTTDATKCTVCPDDFWSNLYKDQCIPKEVEFLSYNDPLGISLTTASLLGTCFCAFVMVIFVHHHNTPIVRANNSELSFLLLFSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKMAMKWFGAAQQRCTILALTAIQVVICVVWLSTASPTPHKNNLYIRSIIVYECTIGSVTGFSMLLGYIGLLAAVSFLIAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYSVAVEIFAILASSFGLLVSIFAPKCYIILLHPERNNKKAIMGRETH", "length": 888 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LAY5-1", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "Vom2r5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTIAIFSLKFCLILCSLTEPNCFWRIKSSEDNDGDLRSDCGFVLFTHEGPIPEDFYNDIINFRIPARKYEFFLVLLFATDEINKNPYLLPNMSLIFNIIFGLCEDTLGVLDKAYLHQNSNSELFNYYCGINQLCDVDLTGPSWTTSLKLSIYSRTPKIFFGSFNPNLSDHDQFPYIYQIAAKDTYLFHGMVSLMFHFGWTWIGLVISDDDQGIQFLSDLREEMQRHAICLAFVNMIPETMQIYKTRVKIYDQQLMTSSAKVVIIYGEVNSTLELSFRRWAYLGAQRIWITTSQWDVITHKKDFSLDFSHGTVTFAHHHNDIAVFRNFMQTINTSMYPVDISQSMLQWNHFNCSISKNKKKMDCFTFKNPLEWLIQHTFDMVLSEEGYNLYNAVYAVAHTYHKLIFQQVESQKMEEPKGLFTDCQQVTSLLKTIEFTNPVGELVDTKHKENQCATYDIFITWNFPQGLGLKVKIGSYFPCLPQSQQLHISEDWEWVTGETLIPPSVCSMTCTAGFRKIHQKETADCCFDCVQCQENEIANDTADMEQCVKCPDDSYANLEQSQCLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLYIGHPNQATCILQQTTFAIFFTVAISTVLAKTITVVTAFKLTTPERRIKKIMIKGAINLLIPICTLIQLVLCAVWLVISPPFIDRDIQSEHGKVIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKDMVIVEVFSILASSAGLLGCIFFQKCYVLLVRPDLNVLRK", "length": 842 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LDN1-1", "protein_name": "Vomeronasal 2 receptor, 1", "gene_name": "Vom2r1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTIAFFPLKFCLILCSLTEPNCFWRIKKIEVYDGDLQNDCGFVLFTLESPIEENFYNHIINFRIPARKYEFFLVMFFATDEINKNPYLLSNMSLIFSFIFGMCEDTMGVLDKAYLHQNNYFDLLNYNCGRKKRCDVKLTGPSWKTSLKLSVNSRAPKIFFGPFNPNLSDHDQFPYIYQIATKDTYLLHGMVSLMFHFEWTWIGLIITDDDQGIQFHSDLREEMQRHAICLAFVIMIPESIKLYNTKFKIYDQQLMTSSAKVTIIYGKMISTLELNFARWTYLVARRIWITTSKLDVITYDKDFSLDFFHGTVIFAHHHNDIATFRNFMQIINTSKYPVDISQSMGQWNHFNCSISKNKKKMDFFMLKNPMEWLTQHTFDMVLSEEGYNLYNAVYAVAHTYHELIFQQVESQEMAKPKGLFTDCQQVASLLKTRVFTNPVGELVNMNHKENQCAKYDIFIIWNFPNGLGLKVKIGSYFPCLQQSQHLHISEDWEWVTGETLVPSSVCSETCTAGFRKSHQKQTANCCFDCVQCQENEIANDTDMEQCVRCPDDSYANLEQTQCLQRAVTFLAYEDPLGMALGCMALSFSAITVLVLVTFVKYRDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQATFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRKMMIKVATHLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKVIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVIVEVFSILASSAGLLGCIFVQKCYVLLVRPDLNVLQK", "length": 841 }, "evidence": [ { "id": "RGD:1596944", "url": "https://alliancegenome.org/gene/RGD:1596944#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LKX1-1", "protein_name": "Vomeronasal 2 receptor, 4", "gene_name": "Vom2r4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKMWAFTIAFFSLKFCLILCSLTEPSCFWRIKRSEDNDGDLRSDCGFVLFTLESPIEENFYTRIINFRIPARKYEFFLVLFFAIDEINKNPYLLSNMSLIFSIIVGLCEDTMGVLDKAYSHQSKIFKRINYFCGIKQRCDINLTGPSWTTSLKLSIYSRTPKIFFGSFNPNLSDHDQFPYIYQRANKDTYLFCGMVSLMFHFGWTWIGLVISNDDQGIQFLSDLREEMQRHAICLAFVIMIPETMQIYKTRVKIYDQQLMTSSAKVVVIYGEMNSTLELSFRRWAYLGAQRIWITTSQWDVITNQKDFSLDFSHGTVTFAHHHNDITIFRNFMQTINTSKYPIDISQSMLQWNHFNCSISKNKKKMDCFTFNNPLEWLVQHTFDMVLSEEGYNLYNAVYAVAHTYHELIFQQAESQKMADPKGVFTDCQQVASLLKTRVFINPVGELVNMNHKENYCAKYDIFIIWYFPQGLGLKVKIGSYFPCLPQSQQLHISEDWEWVTEETLVPSSVCSVTCTAGFRKIHQKQTADCCFDCVQCQENEIANDTDMEHCVRCPEDSYANLEQTECLQRVVTFLAYEDPLGMALGCMALSFSAITILVLVTFVKYRDTPIVKANNRILSYILLISLAFCFLCSLLFIGHPNQATCILQQTTFAIFFTVAISTVLAKTITVVTAFKLTTPGRRIRKMMIKGAINLLIPICTLIQLVLCAIWLVTSPPFIDRDIQSEHGKIIIICNKGSVIAFHIVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVQKCYVLLVQPDLNVLQK", "length": 841 }, "evidence": [ { "id": "RGD:1564110", "url": "https://alliancegenome.org/gene/RGD:1564110#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0LQR9-1", "protein_name": "Vomeronasal 2 receptor, 57", "gene_name": "Vom2r57", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADMEKAYTLIVFFLLLRLSFILCGFPEATCFWRINHNEHLESNMRKDCGFILFTIPVHLVEDHFRVLLDFPLPVNTYPYVLVMLFAIEEINRNPNLLPNSTLGFTVLGDQCDITSTNLNNLNMLSKSGEIIPNYICEYSDCDVALTGPTWTVSARVATLLQLFKIPQVMLNVTYGPFYDSLSDRDLFPHLYQIAPKDTSLVLAMVSLMIHFLWKWVGLVILDDDQGVQFLSDMKEEMKINDICLAFVNRIPANMQLYIERAGIYYFQIMTSSANVVIIYGNVNSTLEVSFRRWEMLGIWRLWITTSQWDVISRSRDFTIDSFHGTLSLSHHYREISTFKHFIQKTNFSAYPEAVSLVRLGWIYFNCSVSVSECKTLNHCLSNTILELLLWHSFDMAMNDERYNIYNAVYAVAHAFHNMHLQQVDIKVLESWKGLIPRCMQVNDFLKNIRFINPIGDPVTVNQGRNLDAMYDILNVLHFPQGYVLKVKVGQFSPYFAHDQQLLLSEDMIEWATGSRQFSTSVCSMPCHPGFKKSHPEGKADCCFDCLRCPANEISNTTDSEECVKCPEDWYADTEQTHCLPKAVTFLAYEDPLGMALVCLALCFSVLTALVLGVFLKHRETPIVKANNRTLSYILLTALIFCFLCSLLFVGNPNTTTCILQQTTFGILFTVSVSTVLAKTLTVVLAFRITLPGRRMRGLMVSRIPKYIIPICTVVQIILYGIWLWTSPPFVDIDTHSEHGCITITCSKGSVMAFYCVLGYLGSLALVSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSSKGKVMVAVEVFSILASSMGLLGCIFIPKCYIILLRPDRNSIQKFRDKTHS", "length": 859 }, "evidence": [ { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M0L6-1", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "LOC108348097", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADMEKAYTLIVFFLLLRLSFILCSFPEASCFWRINHNEHLESNMRKDCGFILFTIPVHLVEDYFRVLLDFPLPVNTYPYVLVMLFAIEEINKNPNLLPNSTLGFTFLGDQCDITSTNLNNLNMLSKSGEIIPNYICEYSDCDVALTGPTWTVSARVATLLQLFKIPQVMLNVTYGPFHDSLSDHDLFPHLYQIAPKDTSLVLAMVSLMIHFIWKWVGLVILDDDQGVQFLSDMKEEMKINEICLAFVNMIPANMQLYIERAETYYFQIMTSSAKVVIIYGNVNSTLEVSFRRWEMLGIWRLWITTSQWDVISRSRDFTIDSFHGTLSLSHHYREISTFKHFIQKTNFSAYPEAVSLVRLGWIYFNCSVSVSECKTLNHCLSNTILELLPWHSFDMAMNDERYNIYNAVYAVAHAFHNMHLQEVDIKVWESWEGLIPRCMQVNHFLKNVRFINPIGDPVNINQGRNLDAMYDILNVLHFPQGYVLKVKVGQLSPYFAHDQQLFLSEDMIEWATGSRQFSTSVCSMPCYPGFKKSHQEGKADCCFDCSRCPANEISNTTDSEECVKCPEDWYANTEQTHCLPKAVTFLAYEDPLGMALVCLALCFSVLTALVLGVFLKHRETPIVKANNRTLSYILLTALIFCFLCSLLFVGNPNTTTCILQQTTFGILFTVSVSTVLAKTLTVVLAFRITVPGRRMRGLMVSRISKYIIPICTVVQIILYGIWLWTSPPFVDIDTHSEHGCITITCSKGSVTAFYCVLGYLGSLALVSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSSKGKVMVAVEVFSILASSMGLLGCIFIPKCYIILLRPDRNSIQKFRDKTHS", "length": 859 }, "evidence": [ { "id": "RGD:11482623", "url": "https://alliancegenome.org/gene/RGD:11482623#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M8M8-1", "protein_name": "Vomeronasal 2 receptor, 72", "gene_name": "Vom2r72", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFPITFLILKFSLIYFHLTEPSCFWRIKNSEETDGDLRSDCGFVLLAFEEPIEENYYNELINFRIPATKYEFFLVMFFATDEINKNPDLLPNMSLIFNLVGRMCEDTLGLLDEIYSQENKTSYIINYVCGIELSCDIDLIGPSRTTSLKLAIHSMMPKVFFGPFNSNLIDHDQFPYIYQIAIKDTCLPHGMVSLMLQFGWTWVGLIISDNDQGIQFFSDLREEMQRHGICLAFVNVIPETMQRYSTRAKIYDKQLMTSSAKVVIIYGEMNSTLEVSFRRWAYLGVQRIWVTNSQWDVIINKRDFSLDFFHGTVTFAHHHSGMTIFRNVMQTMNTSKYPIDLSQSMLGWNYFNCSISENRHSKTDHFTFNNTLEWLALHKFDMVLSEEGYNLYNAVYAVAHTYHELISQNVESQKVAEPKGLFTDCQQVASLLKATVFTNPVGELVNMNHRENQCAEYDIFIIWNFPEGLGLKVKIASYFPCFPHNQQLHTSEDLEWATEGTLVPSSMCSATCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCARCPDDKYANSEQTYCLQRTVSFLAYEDPLGMALGCMALFFSAITILVLVTFVKYKDTPIVKANNCILSYILLISLIFCFLCSLLFIGHPNKATCILQQTTFGVFFTVAVSAVLAKTVTVVMAFKLTTPGRRMRGMLASGATNLVIPICTLIQLVLYGIWLAISPPFIDRDIQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSITVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDLNFLQK", "length": 843 }, "evidence": [ { "id": "RGD:1597414", "url": "https://alliancegenome.org/gene/RGD:1597414#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0T300-1", "protein_name": "Olfactory receptor CD2 precursor", "gene_name": "olfcd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANTLSLLLLLLLLHGHFLPATVQICDLVGQSALPVLSAERDINIGAIFSIHRNALLRLYPFTSKPEPTTCVRLNLREFKFAQTFIFAIEEINNNTQLLPGVTLGYKIYDACNAISPTLVSGMALINGYENTLSDTSCSQPPAVQAIVGESSSSPTTALAALVGPFNIPVISHFATCACLSNRKRYPSFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGITAFEDAAKQEGICIEYSEAILRTDPQEQFRKTVEVIKKGTSKVVVAFISFGDFAPLVKVIAENNITGLQWVGSESWITSRNLAETKEYSFLSGAVGFAIVNAKLVGLKEFLVNVHPDQEPKNKLLKEFWETAFQCSFSNSDSALCTGSEKLGELKNEYTDVSELRIEHKAYAAVYAVAHTLHNVFKDVKAPNNSKRELPTPQKVLQYMRNLSFTIKTGENIFFDASGDPVARYDLVNWQTAEDGSLQFKHVGIYDSSLPSKQRLQVNQEIMLWAGKSGLLPLSVCTESCLPGTRKAVQKGRPVCCYDCIPCAEGEISNSTDSSDCFSCDLEYWSNEKKDRCILKVVEFLSYAEIMGIILCIVSFIGLLLTVMVTCLFYLHKETPIVRANNSELSFLLLFSLSLCFLCSLTFIGRPTQWSCMLRHTAFGITFILCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLVQVIVCLLWLTLSPPYPYMNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSSPGKYTVAVEIFAILVSSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKL", "length": 848 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0T301-1", "protein_name": "Olfactory receptor CQ19 precursor", "gene_name": "olfcq19", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWVILNISIYLIFNFIMSASILGSNTCQLQGHFRLNEMYHDGDVILGGLFEVDFLTVFPDLDFKTEPEPPYCVQFDMESFQQAQTMAFAIDEINKNPNLLPNITLGYHLFDNCVMLGMAFRAAISMASGTEEFFNNINCTGPPPVIGIVGDSSSTVSIAISSILGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKYFRWTWVGLIYSDDDYGVYAAQSFQQEMQLFGGCVAFSEVLPHDNNLEDIKHITKMIQASTARVIVVFSTPSFLIPLIDELVLQNMTDRQWIASEAWATSFVHHSPRLLPFLKGTLGIAIRRGEIQGLYEFLLRLQPTNDPKNNMIRIFWEIMFGCNFETGGKKNSGDQVINICTGQEDLRTTKTPYTEVSELRASYNVYKAVYALAHALNDLMQCEDGRGPFSVNSCADITNLKPWQLVHYLQNVNFTTDFGDHVSFDKNGDALAIYDVLNWQPSSDGSIRAQTVGVVNEEVATGMVLTLDEDALYWNFESKKPPSSVCSESCAPGTRLATIKGLPVCCFDCLPCGDGEISNITGAVECTMCPDEFWSNLDKDQCIPKEVEFLSYEDPLGISLTTASLLGTCFCVLVMFVFAVHRNTPIVRANNSELSFLLLLSLKMCFLCALLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPESKGAMKWFGAVQQRCTVLVLTAIQVVICAVWLSTASPAPHKNNQYIRSKIVYECAIGSVAGFSMLLAYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIILLHPERNTKKAIMGKEAQNT", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2BE32-1", "protein_name": "Vomeronasal 2, receptor 121", "gene_name": "Vmn2r121", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLCAFTISFLFLKFSLILCCLSEPSCFWRIRNSEDSDGDLQRECHFYLWLIDESIEDNFVSDLNFRIAASEYELLLVIFFATDEINKNSYLLPNMTLMFSIIGGNCHDLLRSLDQEYTEIKGHMNFVNYFCYLDDSCAIGFTGPSWKTSLKLGLHSSMPLVFFGPFNPNLRDHDRLPHVHQVATKDTHLSHGMVSLMFHFRWTWIGLVISDDDQGIQFLSDLREESQRHEICLAFVNMIPENMQIYMTRATIYDKQIMTSSANVVIIYGEMNSTLEVSFRRWEELGAWRIWITTSQWDVIKNKKEFTFNLFHGTITFAHHKVEIPKFKKFMQTMNTAKYPVDISHTILEWNYFNCSISKNSSKMDHMTFNNTLEWTALHNYDMAMSDEGYNLYNAVYAAAHTYHEHILQQVESQKKAKPKRYFTACQQVSSLMKTRVFSNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYIPCFPKSQQLHICDDLEWAMGGTVPSSVCSVACTAGFRKIHQEETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANIEQTHCLSRAVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQVSCILQQTIFGVFFTVSVSTVLAKTITVVMAFKLTTPGRRIRGMMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTVILCNKGSVIAFHVVLGYLGSLALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWITFLPVYHSTRGRVMVVVEVFSILASSAGLLMCIFVPKCYVILIRPDSNFIKKHKGKLLN", "length": 847 }, "evidence": [ { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3YWE3-1", "protein_name": "Vomeronasal 2, receptor 84", "gene_name": "Vmn2r84", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMCALTISFLLLKFSLILCCLKEPICFWRIKSSEYNDGNLQSECGYFVWTMKKLMKDDFYNVWLDFRIPASEYEFVLVMFFATNEINKNPDLLPNTSLVFSVMAGNCQDSLGNLDIQYMLTNDSLNYVNYVCDIDDSCAIGLTGPSWKTSLKLAIDSWTPTVFFGPFNPKLSDHDHFPYVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGVQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWAYLGARRIWITTSQWDVITNKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSVLRWNYFNCSVSKNSIKMDHFTCENPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILQQVESQKMAEDKGEYTECQQLAPLLKTRVFTNPVGEMVNMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTSVPSSMCSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETDMEQCVRCPDDQYANLEQTHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYRDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGGRMRGMMMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIDRDIQSEHGKTVIFCNTGSVLAFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYAILVRPDSNCIQKYKGKLLY", "length": 849 }, "evidence": [ { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZDW0-1", "protein_name": "Vomeronasal type-2 receptor 116-like", "gene_name": "LOC108348195", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLTLILLFFLLNIPLLVASFIYPRCFWSMKKNEYQDRNLGTGCMFFILAVQQPVKKEYFSHISNIQTLTENQKYPLALAFSMNEINNNPALLPNMSLVFQFSEYVCFLESQYKHLFSLDLQNHEILPNFICTEDIKCGVVLTGLSLVTTVTLHIILNNFIFKQFCHLTYGHFHPVLDDHENFPHLYQMASDDTSLALALISFIIHFSWNWVGLAISDNDQGTHFLSYLRREMEKNTVCFAFVNIIPVNMNLYMSRAELYYSQIMTSSANVVIIYGDTGNTLAVSFRMWDSLGIRRLWVTTSQWDVTPFKKDFTFDNGYGTFGFGHRHSEISGFKYFVQTLNPFKYSDEYLVKLEWMYVNCKILENKCKTLKNCSFNHSFEWLMTHTFDMAVIEGSYEIYNAVYAFAHALHEMTLPNVDNLLLDNYKEQYYNCKKVYSFLSKTQFTNPVGDTVNMNQRNKLKEEYDIFYNWNFPQGLGFKVKIGIFSPYFPKGQQLHLCENLIEWSTGSIQMPTSVCSADCGPGFRKVWKNGMPACCYDCSPCPENEISNETNVELCVQCPEDQYANQEQNHCIHKARIFLTYDEPLGMALSLMALCLAALTVVVLGIFVKHHRTPIVKANNCTLTYILLIALIFCFLCPLFFIGHPNSATCILQQITFGVVFTLAISTVLAKTTTVILAFRVTAPHRMMKYFLVSRASNYIIPICTLIQIIVCAIWLGASPPSVDIDAQSEHGHIIIVCNKGSITAFYCVLGYLACLAFVSFTLAFLSRNLPVTFNEAKSMTFSMLVFCSVWVTFLPVYHSTKGKVMVVVEIFSTLASSAGMLGCIFVPKCYTILCRPDRNSLQMIKEKSSSHTHIL", "length": 857 }, "evidence": [ { "id": "RGD:11359049", "url": "https://alliancegenome.org/gene/RGD:11359049#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZQ04-1", "protein_name": "Vomeronasal 2 receptor, 67", "gene_name": "Vom2r67", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTVAFLFLKFSVILCRTQLTEPNCFWRIKNSEDNDGDLQNDCGFILFTFKGRIEENFYNKLLNFINFRIPARKYEFFLVMFFATDEINKNPYLLSNMSLLFSIIFGMCEDTLGIVDEVYSQSNKGLAFTNFICGVESTCDIQLTGPFWTTSLKLAIYSKAPKLFFGPFNPNLNDHVQFPYVHQVASKDTCLSHGMASLMLHFKWTWIGLAISDDDQGIQFLSDLKEEMQRHGICLAFVNMIPENMQIYMTMAKIYDKQIMTSSAKVVVIYGKINSTLEVSFRRWGNLGAHRIWITTSQWDVITNIKDFNLDFFHGTVTFAHHHSDIAEFRNFMQTINTSKYPVDISQSMLGWNHFNCSISKNNSKIDYFTFNNPLEWLAQHTFDMVLSEEGYNLYNAVYAVAHTYHELILQQVESQKMEEPKGVFTDCQQVASLLKTRVFTNPLGELVNMNHRENQCIEHDIFIIWNFPQGLGLKVKIGTYFPYFTHNQQLHISEDLEWATGGTLVPSSMCSMTCTAGFRKIHQKETADCCFDCVQCPENEVSNDTADMEQCVRCPDDSYTNLEQTQCLQRTVSFLAYEDPLGMALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQDTCILQQTTFGVFFTVAISTVLAKTITVVTAFKLTTPGRMIRRRMIKVATNFLIPICTLIQLALCGIWLGTSPPFIDRDIQSEHGKVIIICNKGSIIAFYFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMIVVEVFSILASSAGLLGCIFVPKCYVLLVRPDLNVLQKKDELLYQ", "length": 854 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZXT3-1", "protein_name": "Vomeronasal 2 receptor, 69", "gene_name": "Vom2r69", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKKLCAFTVSFLFLKFSLILCSFTELSCFWRMKNSEDSDGDLRSDCGFVLLTTKKNIEDFYNDINEVRIPARRYEFFLVMFFATDEINNNPYLLPNISLIFSIIAGLCEDTLGVLDEIYSQQNNSWNIVNYICEKGQRCDIELTGPSWKASVKLSIHSMIPSVRMCDTGCVFFGPFNPNLSDHDQFPYMYQIATKDTCLSHGMVSLILHFRWNWLGLVISDDDQGIQFLSDLREEMQSHGICLAFVNMIPETMQVYMIKAKIYDKQIMTSSAKVVIIYGEMNSTLEVSFRRWSYLGVQRIWITTSQWDVITIKKDFNLDFFHGTLTFAHHKVEVAKFRNFMQTRNPAKYPVKFFESVLGWNYFNCSISKNSNLMDHFIFNNTLEWIALNKYDMVLSEEGYNLYNAVYAVAHTYHELILQQTESQNIAEPNGVFIDCQQVASLLKTRVFTNPVGELVNMKHREKQCVEYDIFITWNFPEGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTSVPSSMCSATCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDMYANLEQTQCLQRTVSFLAYDDPLGIALGCMALSFSAITILVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTTPGRRLRGMMITWASNFVIPFCTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTIIICNKGSVIAFHVVLGYLGSLALGSFTIAFLARNLPDRFNEAKFLTFSMLVFYSVWITFLPVYHSTRGKVMVVVEVFSILASSADLLGCIFVQKCYIILVSSNSNFLHK", "length": 849 }, "evidence": [ { "id": "RGD:1564750", "url": "https://alliancegenome.org/gene/RGD:1564750#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A8G4-1", "protein_name": "Vomeronasal 2 receptor, 60", "gene_name": "Vom2r60", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMLLLIFMFLLLQYSSDVYSFDRSSCAAKTKTSVYKDGDMVLAAFLPLFTITIDSASDNQSNNNFYIHQHVKECKFIHSFHFIVLAMVYAIEEINRNPHILPNVSLGYDIYNVLFNEWWILNRCITWLSGPKKYVPNYTCRREMKSIAALTGISWIISTNIGTLLELYKYPQLTIGSFDPNLNNHEQFHDIYQIAYKDMSLTHGIVSLLNYFHWNWVGLIVSEGQNGFQIISELRAEMDRNKICVDFVEMIRVSEVSYLPSYLLSPTHLAKSTANVIITYGDSDFMRGFLFYLRQILVTRKVWIMNSDWDVIIQSKHFILQSFHGSLIFAHHHKETSGYRNFIQTVHPSKYPEDFYLTRFWFYFFNCSFADDDCNTLENCLPNASLHETPGSHFDMVMTEFAYNIYNAVYAVAHSLHKMLLQQVEVTPVKEAEDLIFSAWQLHPFLKNMQFTNPAGEQVNLNEKMKLNADYDILNYWNFPEGLQLKVKVGQFSPYGPLGQQLSLSEDTIEWPTEITETPRSICSESCGPGFRKSLPEGKVSCCFDCVPCPENEISNETDVDQCMQCLDHQYANTAQNHCLQKSMTFLDYEDPMGISLSCIALCFSALTSLVLSIFLKQKNTPIVKANNRTLTYILLIALNFCFLCSFLFIGHPNTATCILQQTTFAVVFTVAVSTVLAKTITVVLAFKVTAPGRRIRWLLVTRAPNFIVPICTLIQIILCGVWLGNSPPFIDTDTRSEHEHIIIMCNKGSVTAFYCVQGYLGALALGSFTLAFLARNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVVVEVFSILVSSAGLLGCIFAPKCYIILLRPQRNSIQGHRDKIHYNYKTS", "length": 864 }, "evidence": [ { "id": "RGD:1560561", "url": "https://alliancegenome.org/gene/RGD:1560561#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PYF5-1", "protein_name": "Vomeronasal 2, receptor 17", "gene_name": "Vmn2r17", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLCVFTISFLLMTFSLFLCSLTGPSCFWRIQNNEDNDGDLHRDCGFFLFTSEEPIKEDFYHFCIDFRIPARRYEVFLVMFFATDEINRNPYLLPNMSLIFCLIVGMCGDTLGYLEETHSPNNTWNSINYNCEIRPICDIELTGPSWTTSVKLAINSRKPKVFFGPFNSHLSDHDQFPYIYQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQSIQFLSDLREAMQRHGICLAFVNMIPENMQIYMTRGKIYDKQIMTSSAKVVIIYGEMNSTLEVSFRRWAYLCARRIWITTSQWDVITNKRDFSFDFFHGTVTFAHHNGEIVIFRNFLQTVNTSKYPLDISQTMQEWNYFNCSISKNSNSKMDHFTFNNTLEWTALQKLNMVLSEEGYNLYNAVYAVAHTYHELILQQVEFQKMAEPKGIFTDCQQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFNIWNFPQGLGLRVKIGSYYPCFPQNQQLHISEDLEWATGGTSVPTSMCSVTCTAGFRKIHQKQTADCCFDCAHCPENEVSNETADMEQCVRCPDDKYANLEQTHCLQRAVSFLAYEDPLGMALGCMALCFSALTLLVFFTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVVMAFKLTAPGRRVRGMLVAGAPNLAIPICTLIQIVLCGIWLVTSPPFIGRDTKSEHGKTILICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLMFCSVWITFLPVYHSTRGKAMVVVEVFSILASSAALLGFIFVPKCYVILVKSDSNFREKYKNKFHY", "length": 849 }, "evidence": [ { "id": "RGD:1597426", "url": "https://alliancegenome.org/gene/RGD:1597426#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PZA6-1", "protein_name": "Vomeronasal 2, receptor 113", "gene_name": "Vmn2r113", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLILLFLLLNIPLIVADFIDPRCFWRIKQNKDEDGNLGSGCSFFIQAVQWPVEKEYFSSILNTQTHTENHKYALVLAFSINEVNRNSDLLPNMSLIFTFSALICDYESQLKSLIHLSLQNHEIFPNYICNDDVCAVALTGLNWTTTLTLYTILNNFISHQFLHLTYGPFHPVLSDHEEFPYLYQMASEDTSLALAMVSFIIHFSWNWVGLAISDNDKGIQFLSYLRREMEKNTVCFAFVSMIPVNMHLYMTRTEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLDIKRIWVTTSQWAITTGKKDFTFNNLYGTFAFGHHHGEISGFKNFVQTLNLLKYSDEYLVKLEWMYFNCEVSAPKCKTLKNCSSNHPLEWLMVRTFDMAFTEGSYAIYNAVYAVAHALHELTFQKFDNLPTDNVKEQNYACNKLGSFLRKIHFTNPVEDRVNMNQRNKLQENYDIFYVWNFPQGLGLKVKIGIFSPYIINGQQLHLSEDMLEWARGSTQMLTSVCSADCGPGFRKFGKNGMPACCFDCSPCPENEISNETNVELCVPCPEDQYANTEQNHCIHKALIFLTYKDPLGMALSLMALCFSAFTAVVLLVFVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCILQQVTFGVAFTVAVSTVLAKTITILLAFRVTAPQRMMKYFLVSGTYIYIIPICTLIQVIVCAVWLGAAPPSVDIDARSEHGHIIIVCNKGSVSAFYCVLGYLACLAFGSFTLAFLSRNLPSTFNEAKSITFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSTLASGAGMLICIFVPKCYIILFMPDRNSLQMIRKKSSSHAHLS", "length": 856 }, "evidence": [ { "id": "RGD:1559687", "url": "https://alliancegenome.org/gene/RGD:1559687#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PZX4-1", "protein_name": "Vomeronasal 2, receptor 87", "gene_name": "Vmn2r87", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMCVLTTSFLFLKFSLILCCLTEPICFWRIKDSEYNDGELQSECGFFLWTMEKPMEDDFYNVRFDFRIPASEYEFVLVMFFATDEINKNPDLLPNTSLVFSVIGGKCQDSLGLLGEEYILINDSLNYVNYVCKADDTCVIDLTGPSWKTSLKLAIDSWTPKVFFGPFNPNLSDHDRFPYVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGARRIWITTSQWDVITNKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSVLRWNYFNCSVSKNSIKMDHFTCKNPLEWTALHNYDMALSDEGYNLYNAVYAVAHAYHEHILHQVESQKMAEDKGKYTECQQLAPLLKTRVFTNPVGELVNMNQREYQCAEYDIFIIWNFPQGLGLKVKIGNYFPCFPRSQQLHISEDLEWVTGGTLVPSSMCSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEQSHCLQRTVSFLAYEDPLGMVLGSMALSSSAITILVLVTFMKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIEHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGKRMRGMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIDRDIQSEHGKTVIFCNKGSVIAFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKIMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSNFIQKYKGKLLY", "length": 848 }, "evidence": [ { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q0E7-1", "protein_name": "Vomeronasal 2, receptor 115", "gene_name": "Vmn2r115", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLLADFISPRCFWKMKQNENRDRNQGTGCTFMIHAVQRPVEKEYFSHILNIQTHTENHKYALALAFSIYEINMNPDILPNMSLIFEFSVHNCVWESKLMSFMHVSLQNYDIFPNYLCKEYTKCAMALTSLNWATTVKFNTILNNFISQQFFQITYGPFHPVLSDHEKFPYLHQMASDHTSLAFGLVSFIIHFGWNWVGLVISDNDQGIQFLSYLKTEMEKNTICFAFVNMIPMSMNLYMSKAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWNVSPGMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQITFQKFDNLPKDNGKEHNYSCKKLYSFLRKTQFINPVGDRVNMNQRDKLQEEYDIFYIWNFPHGLGFKVKIGIFSPYFPNGQQVHLSEDMIEWAKGSAQMPTSVCSADCGPGSRKFRMDGMAACCFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNHCIRKIVVFLSYEEPLGVALSLISLFFSAFTIVVLGVIVKHHSTPVVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGIVFTVSVSTVLAKTITVVLAFKIIASQRMMKYFLVSGAINYIIPVCILIQVIVCAVWLGASPPSVDIDGQSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVPKCYTILFRPDQNSLEMIRVKSSSNARSS", "length": 857 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q1C1-1", "protein_name": "Vomeronasal 2, receptor 118", "gene_name": "Vmn2r118", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMFTSIFIVLLLKLPLLLCNSAENMCFWRVKLNENCDGDLPQDCAFLLYTQVDPAPKDFLKYLFKSCLPSKIHQYLLSLYFAMEEINSNPYLLPNVSLGIEYFKGKCNGYLSLFTNLNIMTKYYHTFPNYICDPGACEIALTGPLWISSAQVATILQLKFIPQVRQITYGPFYPLLSDQSKFPNLHQIAPKNRFLPEAIVSLLFHFSWIWVGLVIQDDDQGIQFLLDIKEEMQRNGVCLAFVNVIPQNMHLFTTRAEKYYNQIITSSANVVILYGELNTALEVSFKHWKYLGTQKIWFTTSQWDAITREKDFSLTSFYGTLTISQYHGDVSTLNNFFQGANLSKDTHYFSSERLGWMYFNCSILKSNCKTPNQCTSSNLLEWLPRHSFDMAMNDESYNIYNAIYAVAHALHEMVLQKIDFQQLENVTQLMQECVQIHAFLENMQFLNPIGDVVIINQQAKTDAEYEIYMIWNFPQGLGVKVKIGRFYSYFLHDQKLYLYEDMIQWASGYSQIPPSVCSVSCAPGFKKFYLEEKPSCCFDCSPCPENEISNATDLTQCVKCPDGQYANIERNHCFPKVVTYLAYADPLGIVLACMALFLSMLSVLVLGIFVKNQYTPIVKANNRTLSYILLISLTLCFLCSLFFIGHPSTARCLLQQITFGILFTVAVSAVLAKTITVLLAFSITIPGRRVKWLLLFGTHKVIIPICSLFQLIICGFWLGLSPPFVERDTHTEHGHIIIMCNKGSLIAFYSVLGYLGCLALASFIMAFLVRNLPDTFNEAKFLTFSMLVFCSVWVTFLPVHHSTKGKAMVAVEVFSILASSAGLLGCIFIPKCYIIVLRPDRNFIQRSKGKNHS", "length": 853 }, "evidence": [ { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q281-1", "protein_name": "Vomeronasal 2, receptor 114", "gene_name": "Vmn2r114", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLLADFISPRCFWKMKQNENRDRNQGTGCTFMIHAVQRPVEKEYFSHILNIQTHAENYKNVLALAFSIYEINRNPDILPNMSVRFTISKYNCYWESELMSLIHLSLQNHDILPNYMCKELTRCTMALTRLNWVTTVKLNTILNNFISQQFFQITYGPFHPVLSDHEKFPYLYQMASDHTSLALALVSFIIHFSWNWVGLAISDNDQGIQFLSYLRRVMEKNAVCFAFVNMIPMSMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQIAFQKFDLPKDNGKEHNYSCKKLYSFLRKTQFTNPVGDRVNMNQRDKLQEEYDIFYIWNFPQGLELRVKIGMFSPYFPNGQQVHLSEDMIEWAKGSAQMPTSVCSAECGPGSRKFRMDGMAACSFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNHCIRKTVVFLSYEEPLGVALSLISLFFSAVTIVVLGVIVKHHSTPVVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGVVFTVSVSTVLAKTITVVLAFKITASQRMMKYFLVSGAINYIIPFCILIQVIVCAVWLGASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGRVMVAVEIFSILASSAGMLGCIFVPKCYTILFRPDQNSLEMIRAKSSSRAHIS", "length": 856 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q4X4-1", "protein_name": "Vomeronasal 2, receptor 11", "gene_name": "Vmn2r11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLRTFTISFWLLKFSLILCHVTEPICFWRIKNNKDNDGDLRSDCNYFLWTFEETTEINFYNIVDFRIPTRRYEFFLVLFFATDEINKNPDLLPNISLIFWLFGGQCEDEWGVLDTNYSQNNINVKFINYDCLSPNCYIDLTGPSWKTSLKLPNILTIIVLMWMSHPLFYILQVFFGSFNPNLSDHDQFPYVHQVATKDTLLSHAMVSLMLHFRWTWIGMVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPENMQIYMTRAKIYDKQIMESTAKVAIIYGEMNSSLEVSFRRWEDLGVRRIWITTSQWDVITNKNDFSLDFFHGTVTFEHHHSEIAKFKNFMQTINTDKYPVNISESILGWNYFNCSTSMNSYSKMDHLTFNNTSEWTALHKYDMALSEEGYNLYNAVYAVAHTYHELILLQVESQQMAVPKGTFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFSQGLGLKVKIGSYLHCYPRSQQLHISEDLEWVTGGSSVPSSMCSMTCTAGFRKIHQNETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGIALGCMALFLSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNLVIPICTLIQLVFCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILVRLDSNFLQKYEHKLPS", "length": 861 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q6I0-1", "protein_name": "Vomeronasal type-2 receptor 116", "gene_name": "Vmn2r116", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFLFLNIPLLVADFISPRCFWKMKQNEYRDRHHGTGCIFLILAIQQPVKKEYFSHILNIQTHTENHKYALALAFSIYEINRNPDLLPNMSLIFIFSADSCEWESELSLIRFGLQNSDNLPNYLCEELTKCILALTNMNWATTVTLHTILSNFLSDQLLHITYGTFHPALSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTLCFAFVNMIPLNINLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNKYGTFAFEQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLKWLMVHTFDMAFIEESYYIYNAVYAFAHVLHQFTFQKFDNLPKDNGKEHNYSCKKLYSYLRKNHFINPVGDRVSMNQRDKLQEEYDIVYIWNFPQGLGLRVKIGMFSPYFPNGQQVHLSEDMLKWARGSTQVPTSMCSADCGPGSRKFRMDGMAACCFHCKPCPENEISNETNVDNCVQCPEDQYANTEQNHCIRKAVVFLSYEEPLGVALSLLSLCFSAFTTVVLGIFVKHHNTPIVKANNRTLTYLLLISLIFCFLCPLLFIGHPNSATCILQQLTFGVVFTVSLSTVLAKTITVVLAFKIIASQRMMKYFLISGAINYIIPICILIQVIVCAVWLRASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLAILAFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVPKCYTILFRQDQNSLEMIRVKSSSNVHVS", "length": 856 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q759-1", "protein_name": "Vomeronasal 2, receptor 14", "gene_name": "Vmn2r14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNLRGFGLSFMLLKFSLIWCHLTEPICFWRIKNNEDNDGDLRSDCGFFLAAVEGPIDHTYNISDFRIPARRHEFFLVLFFATDEINKNPYLLPNMSLIFPEDPGQCEKLLGELDKIHSEAKFTVDFTDYICAGYGTCYIGLIGPSWKTSVKLSTNSGTPRVFFGPFNPKLSDHDQFPYVHQVATKDTHLSHGMITLMLHFRWTWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPEDMQLYMTRAKIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGARRIWITTSQWDVITNKNDFSLDFFHGTVTFEYHHSEIAKFKNFMKTMNTDKYPVNISESILRWNYFNCSTSMNSYSKMGHFTFNNTLEWTALHNFDMALSEEGYNLYNAVYAVAHTYHELILLQVESQQTEEPKGTFTDCQQVSSTLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGSYLPCFPQSQQLHISEDLDWATGGSSVPSSLCSVTCTAGFRKIHQKQTADCCFDCDQCPENAVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCMALTFSALTVLVLVTFVKYKDTPIVKANNRILSNILLISLVFCFLCPLLFIGHPNKATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTSPGGKMRGMLASGAPNLVIPICTLVQLVLCGIWLVTSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFVPKCFVILVRPDSNFLQKYKDKLFY", "length": 848 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LNQ1-1", "protein_name": "Vomeronasal 2 receptor, 68", "gene_name": "Vom2r68", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKELCTFTISFLLLKFSFIMWGLTEPSCFWRIKNNGDNDGDLRTDCGFVLFTRQEPIEENFYNEIVYFRIPARSYEFFLVMFFATDEINKNPYLLPNMSLIFSLIVGMCEDTLEYVDTNYSFKRNTLNIVNYNCYLRARCYIQLTGPSWKTSLKLTINSRKPKVFFGPFNPNLSDRDQFPYVNQIARKDTFLSHAMISLMLFFEWTWIGLAISDDDQGIQFLSVTREVMQKHSICSAFVNVIPENMQIYMARANIYDKQIMTSSAKVVIIYGERNSTLEVSFRRWEYLGAQKIWITTSQWDVITNKRVFSLDFFHGTVTFAYHNGRIPKFRNFMQTMNTSKYPVDISQTILEWNYFNCSIFKNSDSEMNHFTSKNTEEWLAQHKFDMVLSEEGYNLYNAVYAVAHTYHELILQEVESQKILRHKGRFINCQQVASLLKTRIFMNPVGELVNMNQRENQCAEYDIFNIWNFPQGLGLKVKIGSYFSCFPQSQQLQISEDLKWATGGTSVPTSMCSVTCTAGFRKIHQNEAAHCCFDCALCPENEVSNDTDMEQCVRCPDDKYANLEQTYCIQRHVSFLAYEEPLGLTLGCMALCFSALTILVLVTFVKHKNIPVVKANNCILSYILLISLIFCFLCSLLFIGHPKKTTCILQQITFGIFFTMAISTVLAKTITVVMAFKLTTPGRRMRRILASGAPNLIIPICTLIQLVICGTWLATSPPFIDRDIQSEHGKVIIICNKGSVTAFHFVLGYLRSLALGSFAVAFLARNLPDRFNETKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCVFIPKCYVILVRPNSNFLQKYKNKLLY", "length": 849 }, "evidence": [ { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3UW56-1", "protein_name": "Vomeronasal 2, receptor 85", "gene_name": "Vmn2r85", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMCSLTMSFLFLKFSLILCCLTEPICFWRIKSSEYNDENLQSECGYFLWTMKKLMKDDFYNVRLDFRMPAREYEFVLVMFFATDEINKNPDLLPNTSLVFSVMADKCQDSLGILDLKYMLVNDTLNYVNYVCEADDSCAIGLTGPSWKASLKLAIDTWAPKVFFGPFNPNLSDHDRFPNVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGVQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGAQRIWITTSQWDVITNKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPISISESILRWNYLNCSVSKNSIKMDHFTCKNPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILQQVESQKMVEDKGKYTECQQLAPLLKTRVFTNPVGELVDMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPQSQQLHISEDLEWATGGTSVPSSMCSVTCTAGFRKIHQKETADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANIEQTHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGRRMRGMMMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIERDIQSEHGKTVIFCNTGSVLSFHVVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSHFIQKYKGKLHY", "length": 850 }, "evidence": [ { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8Y4-1", "protein_name": "Vomeronasal 2, receptor 86", "gene_name": "Vmn2r86", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKMCALTISFLLLKFSLLLCCLKEPICFWRIKSSEYNDGDLQSECGYFLWTMKKLMKDDFYNVRLDFRIPASEYEFVLVMFFATDEINKNPDLLPNTSLVFSVMAGKCQDSLGNLDIQYMLINDSLNYVNYVCDIDDSCAIGLTGPSWKTSLKLAIDSWTPTVFFGPFNPNLSDHDRFPNVHQIATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQLHSDLREESQRHGICLAFVNVIPETMKIYMTRGNMYDKQIMTSSAKVVIIYGEMNSTLEISFRRWVYLGARRIWITTSQWDVITNKKDFSLDLFHGTVTFAHHKGWIAKFKNFMQTMNTSKYPINISQSILRWNYFNCSVSKNSIKMDHFTCKNPLELTALHNYDMALSDEGYNLYNAVYAVAHTYHEHILHQVESQKMVEDKGKYTECQQLALLLKTRVFTNPVGEMVNMNHREYQCAEYDIFIIWNFPQGLGLKVKIGSYFPCFPWSQQLHISEDLEWATGGTSVPSSICSVTCTPGFRKIHQKETADCCFDCVQCPENEVSNETVDMEQCVRCPDDKYANLEQMHCLQRAVSFLAYEDPLGMALGCMALSFTAITILVLVTFVKYKDTPIVKANNCILSYILLISLVFCFLCSLLFIGHPNQVTCILQQTTFGLFFTVAVSTVLAKTITVVMAFKLTTPGKRMRGMMTGAPKLVIPICTLIQLVLCGIWLLTSPPFIERDIQSEHGKTVIFCNKGSVLSFHVVLGYLGSLALGSFIVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGKVMVVVEVFSILASSAGLLGCIFVPKCYVILVRPDSNYIQKFKGKLLY", "length": 848 }, "evidence": [ { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N5U4-1", "protein_name": "Predicted gene 14496", "gene_name": "Gm14496", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKQLCAFTISFLLLKFSLILCCLTEPICFWRIKNSEDDDRDLQRECHFYLWAIDKPIEDDFYNIVYNFRIAASEYEILLIMFFATDEINKNPYLLPNITLIFTIIGGHCHDLLGGLDEAYTQINGRVKFVNYFCYSDDSCLIGLTGPSWKTSLKLAMDSSMPMVFFGPFNPNLCDHDRLPHVHQVAPKDSHLSHGMVSLMFHFTWTWIGLVISDDNQGIQFLSDLRKEMQRHGICLAFVNMIPENMQIYMTRATIYDKQIMTSSAKVVIIYGDMNSTLEISFRRWEDLGAQRIWITTSQWDVITNKKDFTLNLFHGTVTFAHYKGEIPKFRNFMQTINTDKYPVDISHTILEWNYFNCSSSKNSSKMDHFTFNNTLEWTALHKYDMALSEEGYNLYNAVYAAAHTYHEHFLQQAESQKRADPKRDFTECQQVSSLLKTRVFTNPVGELVNMMHGENECTEYDIFIIWNFPQGLGLKVKIGSYLPCFPQSQQLHISDDLEWAMGGTSVPSSMCSMTCTAGFRKIHQKETADCCFNCVPCPENEVSNETADMEQCVMCPDDKYANIEQTHCLQRTVSFLAYEDPLGMALGCMALSFSAITTLVLVTFVKYKDTPIVKANNRILSYILLISLDFCFLCSLLFIGHPTQVTCILQQTTFGVFFTVAVSTVLAKTITVVMAFKLTTPGRRMRGMMMTGAPKLVIPICTLIQLVLCGIWLVTSPPFIDRDIKSEHGKTVILCNKGSVIAFHFVLGYLGFLALGSFTVAFLARNLPDRFNEAKFLTFSMLMFCSVWITFLPVYHSTRGKVMVAVEVFSILASCAGLVGCIFFPKCYVILIRSDSIFIQKYKDELHY", "length": 849 }, "evidence": [ { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N621-1", "protein_name": "Vomeronasal 2, receptor 10", "gene_name": "Vmn2r10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNLCVFTLSFFLLEFSLILCHLTEPICFWRINNNEDNDGDLRSDCGFFLAAVEGPTDDSYNISDLRIPARRYEFFLVMFFATDEINKNPYLLPNMSLIFPINHGQCEKTLGDLDKIYSEKNYTVEFTDYICVSFGTCFIALIGPSWKTSIKLSINSGTPRVFFGPFNPKLSDHDQFPYVHQVATKDTRLSHAMVSLMFHFTWIWIGMVISDDDQSIQFLSDMREEMQRHGICLAFVNMIPEDMQLYMTRATIYDKQIMESTAKVVMIYGEMNSTLEVSFRRWEDLSIRRIWITTSQWDVITNKNDFSLDFFQGTVTFAHHVGEIANFRNFLQTMNSEKYTVNISESRLGWNYFNCSISKNSNKKDHFTFNNTLEWTTLHKYDMVLSEEGYNLYNAVYAVAHTYHELVLQQVESQQMTVPKGTFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCTEYDIFIIWNFPQGLGLKVKIGSYLPCFQQSQQLHISEDLEWATGGSSVPPSLCSVTCTAGFRKIHQKQTADCCFDCDQCPENAVSNETVDMEQCMRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCTALSFSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNIVIPICTLIQLVLCGIWLVTSPPFIDRDMQSEHGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTQGTVMVVVEVFSILASSAGLLGCIFLPKCCVLLRIQNSNFLHKYKHELHS", "length": 847 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N674-1", "protein_name": "Vomeronasal 2, receptor 111", "gene_name": "Vmn2r111", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFLLLNIPLLVADFIHPRCFWKMKRNENKDRNQGTGCTFVIHAVQQPVEKEYFSHILNIQTQTENRKYALALAFSINEINRNPDLLPNMSLIFKFSAHNCVWESEIMNLMLLSLQNYDIFPNYLCKEYTKCAMALTNLNWATTVTLYTILNNIISEQFLQITYGPFHPVLSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTVCFAFVNMIPVNMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPRMKDFTFGNKYGTFDFQQHNSEISGFKNFVQTLNSVKYPDDYLVELEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEKSYYIYNAVYAFAHALHQFTFQKFDNLPKDNGKEHNYSCKKVDPSLRKMQFTNPVGDIVNMNQRDKLQEEYDIFYIWNFPQGLGLRVKIGMFSPYLPNGQQVHLSEVIIKWTKGSTQVPTSVCSADCGPGSRKFGMDGMAACCFHCKPCPENEISNETNVDNCAQCPEDQYANTEQNHCIHKAVVFLNYEEPLGMALSLFSLCFSAFTTVILGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCILQQITFGVVFTVALSTVLAKTIVVVLAFKITASQRMMKYFLVSGASNYIILICTLIQVIVCAVWLGASPPSVDIDAQSEHGHIIIVCHKGSVNAFYSILGYLALLSFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGMLGCIFVSKCYTILFRPDRNSVEMTRVKSSFHARVS", "length": 857 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6V1-1", "protein_name": "Vomeronasal 2, receptor 117", "gene_name": "Vmn2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLVSDFIYPRCFWKIKQNEDKNRNQGTECTFMIHAVQRPVEKEYFSHILNIQTHTENHKYALALAFSIYEINRNPDILPNMSLTFKFSNYNCHWKSKYNSFIHLSLQNHDILPNYMCKEFTKCAMALTRLNWATTVKLNTILNNFMSQQFLQITYGPFHPVLSDHEKFPYLYQMASDHTSLALALVSFIIHFSWNWVGLVISDNDEDIQFLSYLRREMEKNTVCFAFVNMIPMSMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQIAFQKLDNLPKDNGKEHNYSCKKLYSFLRKTQFTNPVGDRVNMNRRNKLQEEYDIFYIWNFPQGLGLRVKIGMFSPYFPNGQQVHLSEDMIEWAKGSAQVPTSVCSAECGPGSRKFRMDGMAACCFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNQCIRKTVVFLSYEEPLGMALSLLSLCFSAFTTVVLGVMVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGVVFTVSVSTVLAKTITVVLAFKITASQRMMKYFLVSGAINYIIPICILIQVIVCAVWLRASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYYSTKGKVMVAVEIFSILASSAGMLGCIFVPKCYTILFRPDQNSLEMIRVKSSSNAHVS", "length": 857 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6Z8-1", "protein_name": "Vomeronasal 2, receptor 9", "gene_name": "Vmn2r9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLRTFTISFWLLKFSLIFCHVTEPICFWRIKNNEENDGDLRSDCNFFLWTYDESTEINFYNIVDFRIPARRYEFFLVLFFATDEINKNPDLLPNMSLIVWLLGGQCGDEWSVLYKNYSQENINVEFINYDCLSPDCYIHLTGPSWKTSLKMSIQSRTPKLFFGPFNPNLSDHDQFPYVHQVATKDTHLSHAMVSLMLHFRWAWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPKDMQIYMTRATIHDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGARRIWITTSQWDVITNKNDFSLDFFHGTVTFEHHHSEIAKFKNFMKTMNTDKYPVNISQSIGGWNYFNCSTSMNSYSKMDHLTFNNTSEWTALHNFDIVLSEEGYNLYNAVYAVAHTYHELILLQVESQQTEVRKGIFNDCQQVSSMLKSRIFTNPVGELVNMKHRENQCAEYDIFIIWNFPQGLGLKVKIGSYLPCFQQSQQLHISEDLDWATEGTSVPSSMCSVTCTAGFRKIHQNETADCCFDCDRCPENEVSNETADMEQCVSCTGDKYANLEKTHCLQRAVSFLAYEDPLGMSLGCIALFLSALTSLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNLVIPICTLIQLVFCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCAILVRLDSNFLQKYKDKLPS", "length": 848 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N1X2-1", "protein_name": "Vomeronasal 2, receptor 13", "gene_name": "Vmn2r13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKELCVFILCFLLLKFSLILCHLTEPICFWRIKSNEDNDGDLRSDCGFFLAAVEGPIDQIYNISDFRIPARRYEFFLVLFFATDEINKNPYLLPNMSLISPITSGQCEKTLGDLDKIYSEKNITVEFTDNICVFYGACYISFIGPSWKTSVKLSIHTGTPRVFFGPFNPKLSDHDQFPYVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQGIQFLSDMREEMQRDGICLAFVNMIPGNMQLYMTRAKIYDKQIMESTAKVVIIYGEMNSTLEVGFRRWIHLGVRKIWITTSQWDVVTNKKDFSFNFFHGTVTFAHHIGELVKFRNFLQTMNNEKYPVNISETRLGWNSFNCSISKNSNKKDHFTFNNTLEWTARNNFDMVLSEEGYNLYNAVYAVAHTYHELILQQVESQQMAVPKGIFTDCQQVASLLKTRVFTNPVGELVNMKHRENQCADYDIFIIWNFPKGLGLKVKIGSYLPCFHQSQQLHISEDLEWATGGTSVPSSMCSVTCTAGFRKIHQKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANVEKTHCLQRVVSFLAYEDPLGMALGCMALSFSALTVLILVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQITFGVFFTVAISTVLAKTITVVLAFKLTTPGRRMRGMLASGAPNLAIPICTLIQLVLSGIWLVKSPPFIDRDTQSEHGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILD", "length": 831 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N217-1", "protein_name": "Vomeronasal 2, receptor 12", "gene_name": "Vmn2r12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLCVFILFFMLLKFSLISHHLTEPICFWRIKNNEDNDGDLRSDCGFFLAAVEGPIDQIYNISNFRIPARRYEFFLVLFFATDEINKNPYLLPNMSLISPIASGQCEKTLENLDKIYSEKNHTVQFTDNICVFYETCYISLIGPSWKTSVKLSIHHGTPRVFFGPFNPKLSNHDLFPNVHQVATKDTHLSHGMVSLMLHFRWTWIGLVISDDDQCIQFLSDLREEMQGHGICLAFVNMIPEDMQLYMTRAEIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDKGVRRIWIATLQWDVITNKKDFTLDFFQGTVTFAHHVGDIANFRNFLQTMNNEKYPINISESILQWNSFNCSFSKNSNKKDHFTFNNTLEWTALHIYNMVLSEEGYNLYNAVYAVAHTYHELILQQVESQQTEVPKGTFTDCQQVSSMLKSRIFTNPFGELVNMKHQESQCADYDIFIIWNFPKGLGLKVKIGYYLPCYQRSQQLHIYDLEWATGGTLVPSSMCSVACTAGFRKIHRKQTADCCFDCVQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPLGMALGCMALFLSALMVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCPLLFIGHPNLATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNLVIPICTLIQLVLCGIWLVTSPPFIDRDTQSEYGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVYCSVWITFLPVYHSTRGAVMVVVEVFSILASSAGLLGCIFLPKCCVILLD", "length": 831 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N221-1", "protein_name": "Vomeronasal 2, receptor 112", "gene_name": "Vmn2r112", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFLLLNIPLHVADFIHPRCFWKMKRNENKDRNQGTECTFVIQAVQQPVEKEYFSHILNIQTQTENRKYALALAFSINEINRNPDLLPNMSLIFKFSAENCVWENKLMSLMHSSLQNYDILPNYLCEEYTECVMALTSLNWATTVTLYTILNNFMSEQFLQITYGPFHPVLSDHEKFPYLHQMASDHTSLALALVSFIIHFGWNWVGLVISDSDQGIQFLSYLRREMEKYTVCFAFVNMIPVNMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNKYGTFDFQQHNSEISGFKNFVQTLNSVKCPDEYLVELEWMHFNCEVSASKCKPLKNCSSSYSFDWLMEHTFDMAFIEKSYYIYNAVYAFAHALHQFTFQKFDNLPKDNGKKHNYSCKKVDSSLRKTQFTNPVGDIVNMNQKGELQEEYDIFYIWNFPQGLGLRIKIGMFSPYFPNGQQVHLSEVMIRWAKGSTQVPTSVCSADCGPGSRKFEMDGMAACCFHCKPCPENEISNETNVDNCVQCPEDQYANTEQNHCIHKAVVFLSYEEPLGMALSLLSLFFSAFTTVILGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSVTCFLQQITFGVVFTVALSTVLAKTITVVLAFKITASQRMMKYFLVSGASNYIILICTLIQVIVCAVWLGASPPFVDIDAQSEHGHIIIVCHKGSVNAFYSILGYLALLSFGSFTLAFLSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKVMVAVEIFSTLASSAGILGCIFVSKCYTILFRPDRNSVEMTRVKSSFHAHIS", "length": 857 }, "evidence": [ { "id": "RGD:1583473", "url": "https://alliancegenome.org/gene/RGD:1583473#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2A0-1", "protein_name": "Vomeronasal 2, receptor 15", "gene_name": "Vmn2r15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLRVFTFSLLLLKCFLISCHLTEPICFWRLKNNEDNDGDLRSDCGVFLAAVEGPIDQIYNISDFRIPARRYEFFLVMFFATDEINKNPYLLPNMSLISPVDHGQCEETLGLLDEIYLEKNNSVEFTDYICVFYGTCYIGLIGPSWKTSVKLSIHSRTPRVRMCETRLVFFGPFNPNLSDHDQFPYVHQVAIKDTHLSHGMASLMLHFRWTWIGLVISDDDQSIQFLSDLREEMQRHGICLAFVNMIPEDMQLYMTRAKIYDEEIMTSTAKVVIIYGEMNSTLQVSFRRWEDLGVRRIWITTSQWDVITNKNDFSLDFFHGTVTFAHHVGKIAKFRNFLQTMNSDKYPVNISKSILGWNYFNCSVSKKGNKKDHFTFNNTLEWTALHNFDIVLSEEGYNLYNAVYAVAHTYHELILQQVESQQTAVPKGIFTDCQQVSSMLKSRIFTNPVGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGNYLPCYPWSQQLHISENLEWATGGSSVPSSMCSVTCTAGFRKIHQKQTADCCFDCDQCPENEVSNETADMEQCVRCPDDKYANLEKTQCLQRVVSFLAYEDPLGMTLGCMALTFSALTVLVLVIFVKYKDTPIVKANNRIVSYILLISLVFCFLCSLLFIGHPTQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGGRMRGMLASGAPNLVIPICTLIQLVLCGIWLVTSPPFIDRDIQSEHGKTIIICNKGSVIAFHFVLGYLGALALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILLRPDLTFLQKYKDKLPS", "length": 855 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N472-1", "protein_name": "Vomeronasal 2, receptor 8", "gene_name": "Vmn2r8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKKLRTFTISFLLLKFSLILCHVTDPICFWRIKNNEENDGDLRSDCNFLLWTDYESTEFNFYNIVDFRIPARRYEYFLVLFFATDEINKNPDLLPNMSLIVWLLSGQCGDEWSVLHKNYSQENINVKFINYDCLSPACYIDLTGPSWKTSLKMSIQSRTPKVFFGPFNPDLRDHDQFPFVHQVATKDTYLSHAMVSLMHHFRWMWIGLVISDDDQGIQFLSDLREEMQRHGICLAFVNMIPENMQIYMTRATIYDKQIMESTAKVVIIYGEMNSTLEVSFRRWEDLGVRRIWITTSQWDVITNKNDFSLDFFHGTVTFEHHHSEIAKFKNFMKTMNTDKYPVNISQSIVGWNYFNCSTSMNSFSKMDHLTFNNTLEWTALHNFDMVLSEEGYNLYNAVYAVAHTYHELILLQVESQQTEVPKGIFTDCQQVASMLKSRIFTNPIGELVNMKHRENQCADYDIFIIWNFPQGLGLKVKIGSYLHCFSQSQQLHISEDLEWATGGTSVPSSLCSVTCTAGFRKIHQNETADCCFDCDQCPENEVSNETADMEQCVRCPDDKYANLEKTHCLQRAVSFLAYEDPWGMALGCMALFLSALTVLVLVTFVKYKDTPIVKANNRILSYILLISLVFCFLCSLLFIGHPNQATCILQQTTFGVFFTVAISTVLAKTITVLMAFKLTTPGRRMRGMLASGAPNLVIPICTLIQLFLCGIWLVTSPPFIDRETQSEYGKTIIICNKGSVIAFHFVLGYLGSLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTRGTVMVVVEVFSILASSAGLLGCIFLPKCCVILVRLDSNFLQKYKDKLPS", "length": 848 }, "evidence": [ { "id": "RGD:1585898", "url": "https://alliancegenome.org/gene/RGD:1585898#orthology", "database": "AGR" }, { "id": "RGD:1562697", "url": "https://alliancegenome.org/gene/RGD:1562697#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R9L8-1", "protein_name": "Vomeronasal 2 receptor, 77", "gene_name": "Vom2r77", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMFTSIFIVFLLKLPLLLSNSTENMCFWRANFNENCDGDLLHDCAFLIYTDEEPAPKDFFKYLFKLCLPSKIYQYVLSLYFAIMEINGNPYILPNVSLEIAYFRGECNGYLSLLTNLNIMTKYQHTLPNYVCNPGACEIVLTGPLWKSSAQVATILQLNFIPQITYGPFHPLLSDQIKFPNLHQIAPKDRFLCEAIVSLLFHFSWTWVGLVVEDNDQGIQFLLDIKGEMQRNGVCLAFVNVIPQNMQLFTTRAEIYYNKIITSSANVVIIYGEMNTALEVSFKHWKYLGTQKVWFTPSQWDVITREREFTSTSFHGTFTISQYHGDVSILNNFIYRMNLSKDTHYFSPERLGWMYSNCSLLKSNCKTPNQCTSSNSWEWLPWHSFDMAMNDECYNVYNAIYAVAHALHEMILQKIDFQQRNNVSQLMQECLKVHEFLQKMKFFNPVGDIVVINQRTKRDAEYEIHMVWNFPQGLGMKVKIGRFFSHFLHDQKLYLYEDMIQWALGYSQIPTSICSMSCAPGFKKSYPEEKASCCFACSPCPENEISNATDLAQCVKCPDGQYANIERNHCFPKAVTFLDYADPVGIVLVCMALCLSTLSALILGIFVKKQNTPIVKANNRTLSYILLVSLTLCFLCSLLFIGHPSTARCVLQQITFGTLFTVAVSTILAKTITVLLAFSITVPGRRVTWPLFVASKVIIPICSLFQLMLCGLWLGLSPPFVERDAHSEYGHIIIMCNKGSIIAFYCVLGYLGCLALASFIVAFLGRNLPDTFNEAKFLTFSMLVFCSVWVTFLPVFHSTKGKVMVAVEVFSILTSGAGLLGCIFIPKCYIIVLRQDRNFIKKVKGKNHS", "length": 849 }, "evidence": [ { "id": "RGD:1582883", "url": "https://alliancegenome.org/gene/RGD:1582883#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050419-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-156#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1LV89-1", "protein_name": "Olfactory receptor CQ3 precursor", "gene_name": "olfcq3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLNICLHLSFIFISVNSDSCQIQGHFKLNRMYKDGDYIIGGLFEVQHLKVFPELSFRMEPEQPKCEEFYMSSFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCLKLVVAFRAATTLISGTEETFSNFNCTGPPPVIAIVGDPGSTHSIAVSSVLGLFHVPLISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMVQILKYFGWTWVGVLYSDDDYGIYAAQSFQQEMQRFKGCVAFSEIVPYDNHRDIQRIVAVIKASTARVVVAFSTDLLPLMEELLQQNVTGRQWIASEAWSTSPVLHLPRFVPLVRGTLGIAIHRGKIKGLHEFLLHIQPDNDPTNNMVRIFWENMFGCSFEKGNGYGEKMCTAQEDLNITVNEYNDVSELRASYNVYKAVYALAHALHDLMQCEEGRGPFSGNSCADITKLKPWQMVPYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWHPSSDGLIVVRTVGVVDEGASAGRVLTLDEDAIYWNFETKKPPRSVCSESCPPGTRRAMRKGLPVCCFDCLPCADGEISNMSDATECTSCPNEFWSSPKKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVLAVFAHHHNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAMFGISFVLCVSSILVKTMVVIAVFKSSRPEGKSAVKWFGAVQQRGTVLVLTAVQIVICVVWLSTASPTPHKNILYVRSKIVFECSIGSMAGFAILLGYIGILAAVSFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFIPAYVSSPGKYSVAVEIFAILASSFGLLVAIFVPKCYIIILHPERNTKKAIMGRTAEK", "length": 855 }, "evidence": [ { "id": "MGI:1316730", "url": "https://alliancegenome.org/gene/MGI:1316730#orthology", "database": "AGR" }, { "id": "RGD:1559561", "url": "https://alliancegenome.org/gene/RGD:1559561#orthology", "database": "AGR" }, { "id": "RGD:1562007", "url": "https://alliancegenome.org/gene/RGD:1562007#orthology", "database": "AGR" }, { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3647235", "url": "https://alliancegenome.org/gene/MGI:3647235#orthology", "database": "AGR" }, { "id": "MGI:3761377", "url": "https://alliancegenome.org/gene/MGI:3761377#orthology", "database": "AGR" }, { "id": "MGI:3645796", "url": "https://alliancegenome.org/gene/MGI:3645796#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3642986", "url": "https://alliancegenome.org/gene/MGI:3642986#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3769929", "url": "https://alliancegenome.org/gene/MGI:3769929#orthology", "database": "AGR" }, { "id": "MGI:3643367", "url": "https://alliancegenome.org/gene/MGI:3643367#orthology", "database": "AGR" }, { "id": "MGI:3646965", "url": "https://alliancegenome.org/gene/MGI:3646965#orthology", "database": "AGR" }, { "id": "MGI:3646674", "url": "https://alliancegenome.org/gene/MGI:3646674#orthology", "database": "AGR" }, { "id": "MGI:3647194", "url": "https://alliancegenome.org/gene/MGI:3647194#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "MGI:3649066", "url": "https://alliancegenome.org/gene/MGI:3649066#orthology", "database": "AGR" }, { "id": "MGI:3643045", "url": "https://alliancegenome.org/gene/MGI:3643045#orthology", "database": "AGR" }, { "id": "MGI:3644292", "url": "https://alliancegenome.org/gene/MGI:3644292#orthology", "database": "AGR" }, { "id": "MGI:3761689", "url": "https://alliancegenome.org/gene/MGI:3761689#orthology", "database": "AGR" }, { "id": "MGI:3648972", "url": "https://alliancegenome.org/gene/MGI:3648972#orthology", "database": "AGR" }, { "id": "MGI:3647193", "url": "https://alliancegenome.org/gene/MGI:3647193#orthology", "database": "AGR" }, { "id": "MGI:3761695", "url": "https://alliancegenome.org/gene/MGI:3761695#orthology", "database": "AGR" }, { "id": "MGI:3643806", "url": "https://alliancegenome.org/gene/MGI:3643806#orthology", "database": "AGR" }, { "id": "MGI:3643093", "url": "https://alliancegenome.org/gene/MGI:3643093#orthology", "database": "AGR" }, { "id": "MGI:1316735", "url": "https://alliancegenome.org/gene/MGI:1316735#orthology", "database": "AGR" }, { "id": "MGI:3649165", "url": "https://alliancegenome.org/gene/MGI:3649165#orthology", "database": "AGR" }, { "id": "MGI:3649151", "url": "https://alliancegenome.org/gene/MGI:3649151#orthology", "database": "AGR" }, { "id": "MGI:3761379", "url": "https://alliancegenome.org/gene/MGI:3761379#orthology", "database": "AGR" }, { "id": "MGI:3647034", "url": "https://alliancegenome.org/gene/MGI:3647034#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPM0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPM0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 605, "end_pos": 607, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PPM0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM0" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 571, "end_pos": 827, "start_aa": "Met", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 288, "end_pos": 290 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 605, "end_pos": 607 }, { "start_pos": 92, "end_pos": 94 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPM2-1", "uniprot_ac": "A0A8M9PPM2", "uniprot_id": "A0A8M9PPM2_DANRE", "mass": { "chemical_mass": 135342.0, "monoisotopic_mass": 135342.0 }, "refseq": { "ac": "XP_021333472", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333472" }, "gene_names": [ { "name": "LOC101885004", "type": "recommended", "evidence": [ { "id": "A0A8M9PPM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM2" } ] }, { "name": "LOC101885004", "type": "synonym", "evidence": [ { "id": "XP_021333472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333472" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PPM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021333472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333472" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021333472.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021333472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333472" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPM2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101885004", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENEP-160728-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENEP-160728-67", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PPM2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PPM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "101885004", "url": "https://www.ncbi.nlm.nih.gov/gene/101885004", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885004", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885004", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR31594", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31594", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31594:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31594:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021333472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333472", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PPM2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G441", "url": "https://www.uniprot.org/uniprotkb/A0AC58G441", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G441-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G441-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G448", "url": "https://www.uniprot.org/uniprotkb/A0AC58G448", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G448-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G448-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G477", "url": "https://www.uniprot.org/uniprotkb/A0AC58G477", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G477-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G477-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAITRIIYCESIFLHFFIPRSTNRLQSQMWRVALEAEQFSDFDSLLRSFSFEMHLCIHEILNQKVFQRIGEVLKKKRSNSVHLFLHVKEKFITRPLQMAIFESLPNIATIRIFPQQFQVAVETKLYLQGAVHEMETGHRCVRNLLSVFSKNPRENFEELCRILLTLYEDVKNLDVLSLLQPVFYAMPPTWVVHPSTPSLSLLLQTMKVLNLKKPAELDHATYPLSELKLFLQCIPYITEIRFSAALRQSDDIHKIVKTVADLFILASECGEKELKRLSTACSYSNFPFSGESKILQSIFFLGLFSQLKERSSWQTVLLVLKPILNVAPSVWTVDLLKLEKTSVFTELLKLQALRKPVELMSGSCKKEKLRFFLNCLPYVSEFRCDEQFFQTVCEVLLTDSEWNPKQIAELLRSLGFSISLIGMLSSHLCKAVGSVFEQLEKDCISLNLLPQKISYQGCAYLFSKVRKLKTLRVNEIAASKLTRLARSDKEMHPITVEELSVVLSDCNLQKRELCQLLSSLTSLLRVWTVHSLNLSECQIEPHMFICLLCHQSPLSIRFHEDTLQQLAEVVCDAQDENLTQLFLEKIDGDLSPCCLSWDVLSCLIQVAKKKVTIDLSEDRFNVLNIPRLLPVLDKVCFKSISPLMVRAALKEIYEERAGHLIVKLVQSSANLINLCMRELDSADCKALCFALHYSDGVKLNLLNSVIPNNETDSIVKLMHRVSELRVDRKLLLNFLHMSKNMWKQGHALLTALNNKLDFSFSSSLDSGFAQEKEDLLTLCYMDCEAITSAIETSTFETELILYDCQAEDSALETLFPVLHKVHLRLGKSLLCQLVTLISNAPMAMSLKWASSLSKALGKELDLSDTPLNYRTCESLQLVLDYTEDLTHLNLSHCQITDACLDLFLPHLHKILTLDFTGNYITDKGVLRLRTALDVNHFTKAICLCDNHITEIGLLMEESRFETQPASTRCSQKYITKDLQSNSKTEKSMTAFVQREDTVKEFEPEIAVINGEISYRFQCESEGFFMCGATGLVFGMKSSGCVEYSVVHWDPYHLINTRYEPAGPLFDIKTPAGEIYELHLPHCETHVDAIGNISVIHMHNKDSREFLSPFKISKTHVAVNISGLSTYGTVYENDEQSRSIRGQVLLFHEPDLSEALQRLWVFLLPGNVPLSEIKAQQQEYVYIQTTSD", "length": 1187, "header": "tr|A0A8M9PPM2-1|A0A8M9PPM2_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101885004 PE=4 SV=2 CANONICAL=A0A8M9PPM2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PPM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM2/entry#A0A8M9PPM2-1", "sequence": { "sequence": "MAITRIIYCESIFLHFFIPRSTNRLQSQMWRVALEAEQFSDFDSLLRSFSFEMHLCIHEILNQKVFQRIGEVLKKKRSNSVHLFLHVKEKFITRPLQMAIFESLPNIATIRIFPQQFQVAVETKLYLQGAVHEMETGHRCVRNLLSVFSKNPRENFEELCRILLTLYEDVKNLDVLSLLQPVFYAMPPTWVVHPSTPSLSLLLQTMKVLNLKKPAELDHATYPLSELKLFLQCIPYITEIRFSAALRQSDDIHKIVKTVADLFILASECGEKELKRLSTACSYSNFPFSGESKILQSIFFLGLFSQLKERSSWQTVLLVLKPILNVAPSVWTVDLLKLEKTSVFTELLKLQALRKPVELMSGSCKKEKLRFFLNCLPYVSEFRCDEQFFQTVCEVLLTDSEWNPKQIAELLRSLGFSISLIGMLSSHLCKAVGSVFEQLEKDCISLNLLPQKISYQGCAYLFSKVRKLKTLRVNEIAASKLTRLARSDKEMHPITVEELSVVLSDCNLQKRELCQLLSSLTSLLRVWTVHSLNLSECQIEPHMFICLLCHQSPLSIRFHEDTLQQLAEVVCDAQDENLTQLFLEKIDGDLSPCCLSWDVLSCLIQVAKKKVTIDLSEDRFNVLNIPRLLPVLDKVCFKSISPLMVRAALKEIYEERAGHLIVKLVQSSANLINLCMRELDSADCKALCFALHYSDGVKLNLLNSVIPNNETDSIVKLMHRVSELRVDRKLLLNFLHMSKNMWKQGHALLTALNNKLDFSFSSSLDSGFAQEKEDLLTLCYMDCEAITSAIETSTFETELILYDCQAEDSALETLFPVLHKVHLRLGKSLLCQLVTLISNAPMAMSLKWASSLSKALGKELDLSDTPLNYRTCESLQLVLDYTEDLTHLNLSHCQITDACLDLFLPHLHKILTLDFTGNYITDKGVLRLRTALDVNHFTKAICLCDNHITEIGLLMEESRFETQPASTRCSQKYITKDLQSNSKTEKSMTAFVQREDTVKEFEPEIAVINGEISYRFQCESEGFFMCGATGLVFGMKSSGCVEYSVVHWDPYHLINTRYEPAGPLFDIKTPAGEIYELHLPHCETHVDAIGNISVIHMHNKDSREFLSPFKISKTHVAVNISGLSTYGTVYENDEQSRSIRGQVLLFHEPDLSEALQRLWVFLLPGNVPLSEIKAQQQEYVYIQTTSD", "length": 1187, "header": "tr|A0A8M9PPM2-1|A0A8M9PPM2_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101885004 PE=4 SV=2 CANONICAL=A0A8M9PPM2-1" }, "locus": {} }, { "isoform_ac": "A0AC58G441-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM2/entry#A0AC58G441-1", "sequence": { "sequence": "MRWKQVIDVFSAALRQSDDIHKIVKTVADLFILASECGEKELKRLSTACSYSNFPFSGESKILQSIFFLGLFSQLKERSSWQTVLLVLKPILNVAPSVWTVDLLKLEKTSVFTELLKLQALRKPVELMSGSCKKEKLRFFLNCLPYVSEFRCDEQFFQTVCEVLLTDSEWNPKQIAELLRSLGFSISLIGMLSSHLCKAVGSVFEQLEKDCISLNLLPQKISYQGCAYLFSKVRKLKTLRVNEIAASKLTRLARSDKEMHPITVEELSVVLSDCNLQKRELCQLLSSLTSLLRVWTVHSLNLSECQIEPHMFICLLCHQSPLSIRFHEDTLQQLAEVVCDAQDENLTQLFLEKIDGDLSPCCLSWDVLSCLIQVAKKKVTIDLSEDRFNVLNIPRLLPVLDKVCFKSISPLMVRAALKEIYEERAGHLIVKLVQSSANLINLCMRELDSADCKALCFALHYSDGVKLNLLNSVIPNNETDSIVKLMHRVSELRVDRKLLLNFLHMSKNMWKQGHALLTALNNKLDFSFSSSLDSGFAQEKEDLLTLCYMDCEAITSAIETSTFETELILYDCQAEDSALETLFPVLHKVHLRLGKSLLCQLVTLISNAPMAMSLKWASSLSKALGKELDLSDTPLNYRTCESLQLVLDYTEDLTHLNLSHCQITDACLDLFLPHLHKILTLDFTGNYITDKGVLRLRTALDVNHFTKAICLCDNHITEIGLLMEESRFETQPASTRCSQKYITKDLQSNSKTEKSMTAFVQREDTVKEFEPEIAVINGEISYRFQCESEGFFMCGATGLVFGMKSSGCVEYSVVHWDPYHLINTRYEPAGPLFDIKTPAGEIYELHLPHCETHVDAIGNISVIHMHNKDSREFLSPFKISKTHVAVNISGLSTYGTVYENDEQSRSIRGQVLLFHEPDLSEALQRLWVFLLPGNVPLSEIKAQQQEYVYIQTTSD", "length": 955, "header": "tr|A0AC58G441-1|A0AC58G441_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC101885004 PE=4 SV=1 CANONICAL=A0A8M9PPM2-1" }, "locus": {} }, { "isoform_ac": "A0AC58G448-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM2/entry#A0AC58G448-1", "sequence": { "sequence": "MRWKQVIDVFSAALRQSDDIHKIVKTVADLFILASECGEKELKRLSTACSYSNFPFSGESKILQSIFFLGLFSQLKERSSWQTVLLVLKPILNVAPSVWTVDLLKLEKTSVFTELLKLQALRKPVELMSGSCKKEKLRFFLNCLPYVSEFRCDEQFFQTVCEVLLTDSEWNPKQIAELLRSLGFSISLIGMLSSHLCKAVGSVFEQLEKDCISLNLLPQKISYQGCAYLFSKVRKLKTLRVNEIAASKLTRLARSDKEMHPITVEELSVVLSDCNLQKRELCQLLSSLTSLLRVWTVHSLNLSECQIEPHMFICLLCHQSPLSIRFHEDTLQQLAEVVCDAQDENLTQLFLEKIDGDLSPCCLSWDVLSCLIQVAKKKVTIDLSEDRFNVLNIPRLLPVLDKVCFKSISPLMVRAALKEIYEERAGHLIVKLVQSSANLINLCMRELDSADCKALCFALHYSDGVKLNLLNSVIPNNETDSIVKLMHRVSELRVDRKLLLNFLHMSKNMWKQGHALLTALNNKLDFSFSSSLDSGFAQEKEDLLTLCYMDCEAITSAIETSTFETELILYDCQAEDSALETLFPVLHKVHLRLGKSLLCQLVTLISNAPMAMSLKWASSLSKALGKELDLSDTPLNYRTFLQEIT", "length": 645, "header": "tr|A0AC58G448-1|A0AC58G448_DANRE Computationally mapped isoform of Uncharacterized protein isoform X4 OS=Danio rerio OX=7955 GN=LOC101885004 PE=4 SV=1 CANONICAL=A0A8M9PPM2-1" }, "locus": {} }, { "isoform_ac": "A0AC58G477-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM2/entry#A0AC58G477-1", "sequence": { "sequence": "MRWKQVIDVFSAALRQSDDIHKIVKTVADLFILASECGEKELKRLSTACSYSNFPFSGESKILQSIFFLGLFSQLKERSSWQTVLLVLKPILNVAPSVWTVDLLKLEKTSVFTELLKLQALRKPVELMSGSCKKEKLRFFLNCLPYVSEFRCDEQFFQTVCEVLLTDSEWNPKQIAELLRSLGFSISLIGMLSSHLCKAVGSVFEQLEKDCISLNLLPQKISYQGCAYLFSKVRKLKTLRVNEIAASKLTRLARVWTVHSLNLSECQIEPHMFICLLCHQSPLSIRFHEDTLQQLAEVVCDAQDENLTQLFLEKIDGDLSPCCLSWDVLSCLIQVAKKKVTIDLSEDRFNVLNIPRLLPVLDKVCFKSISPLMVRAALKEIYEERAGHLIVKLVQSSANLINLCMRELDSADCKALCFALHYSDGVKLNLLNSVIPNNETDSIVKLMHRVSELRVDRKLLLNFLHMSKNMWKQGHALLTALNNKLDFSFSSSLDSGFAQEKEDLLTLCYMDCEAITSAIETSTFETELILYDCQAEDSALETLFPVLHKVHLRLGKSLLCQLVTLISNAPMAMSLKWASSLSKALGKELDLSDTPLNYRTCESLQLVLDYTEDLTHLNLSHCQITDACLDLFLPHLHKILTLDFTGNYITDKGVLRLRTALDVNHFTKAICLCDNHITEIGLLMEESRFETQPASTRCSQKYITKDLQSNSKTEKSMTAFVQREDTVKEFEPEIAVINGEISYRFQCESEGFFMCGATGLVFGMKSSGCVEYSVVHWDPYHLINTRYEPAGPLFDIKTPAGEIYELHLPHCETHVDAIGNISVIHMHNKDSREFLSPFKISKTHVAVNISGLSTYGTVYENDEQSRSIRGQVLLFHEPDLSEALQRLWVFLLPGNVPLSEIKAQQQEYVYIQTTSD", "length": 916, "header": "tr|A0AC58G477-1|A0AC58G477_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=LOC101885004 PE=4 SV=1 CANONICAL=A0A8M9PPM2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885004", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885004", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPM2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1091, "end_pos": 1093, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1119, "end_pos": 1121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 577, "end_pos": 579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 709, "end_pos": 711, "annotation": "n_glycosylation_sequon" }, { "start_pos": 889, "end_pos": 891, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PPM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM2" }, { "id": "PS51830", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51830" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FIIND", "eco_id": "ECO_0000259", "start_pos": 994, "end_pos": 1187, "start_aa": "Arg", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1091, "end_pos": 1093 }, { "start_pos": 1119, "end_pos": 1121 }, { "start_pos": 533, "end_pos": 535 }, { "start_pos": 577, "end_pos": 579 }, { "start_pos": 709, "end_pos": 711 }, { "start_pos": 889, "end_pos": 891 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPM5-1", "uniprot_ac": "A0A8M9PPM5", "uniprot_id": "A0A8M9PPM5_DANRE", "mass": { "chemical_mass": 65228.0, "monoisotopic_mass": 65228.0 }, "refseq": { "ac": "XP_021328978", "name": "extracellular calcium-sensing receptor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328978" }, "gene_names": [ { "name": "olfcx3", "type": "recommended", "evidence": [ { "id": "A0A8M9PPM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM5" } ] }, { "name": "olfcx3", "type": "synonym", "evidence": [ { "id": "XP_021328978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328978" } ] } ], "protein_names": [ { "name": "Extracellular calcium-sensing receptor", "type": "synonym", "evidence": [ { "id": "A0A8M9PPM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM5/entry#names_and_taxonomy" } ] }, { "name": "extracellular calcium-sensing receptor", "type": "synonym", "evidence": [ { "id": "XP_021328978", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328978" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021328978.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328978" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "olfcx3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050419-129", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050419-129", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PPM5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PPM5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06364", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06364", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100148278", "url": "https://www.ncbi.nlm.nih.gov/gene/100148278", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100148278", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148278", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24061", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061:SF511", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061:SF511", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021328978", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328978", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050419-129", "url": "https://zfin.org/ZDB-GENE-050419-129", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAGVYKVLISFWPLLCIGVQSQYKSKENCVFQGDEDTYSFYQRGDVVLGGIFPLHSSPVSSLFSFRTKPKPTSYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPEKGSGQSCEDIQMQPSPVIVGDAASGVSMTVLRTLGSFKIPLVSYFASCSCLSNKREFPAFMRTMPSDLFQIKALVKLINYFQWTWVGLIGVNSDYAHFAIQLFLKESEQFNICPAYVHFYPVVLMEDALEELVNILKASSATVIINFSGESELHSILKECRRQNVTHLQWIASEAWATSKSLWEEFGDLLKGTLGFAIHRADIPHLGSYLKEIRPQTSHFLSEFWEETFRCRLNGSLNTHAHGEQAQNWPACNGSENLDNVYTTYSDVSQLRVSYNVYKAVYLIAHALHDMSTCVPGKGPFQNGTCGSLYQIQPWQLLYYMKQANFTILGEEVRFDENGDPIASYDLMNWQRGSDSSLQLVRVGFYDASLEDDKDLVVEESVIMWHRAEKVCAIPRITRYWSLSLFFLQLYFMILTGLNKMEYCNFKWKCNIGFIMH", "length": 571, "header": "tr|A0A8M9PPM5-1|A0A8M9PPM5_DANRE Isoform 1 of Extracellular calcium-sensing receptor OS=Danio rerio OX=7955 GN=olfcx3 PE=4 SV=3 CANONICAL=A0A8M9PPM5-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PPM5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM5/entry#A0A8M9PPM5-1", "sequence": { "sequence": "MAGVYKVLISFWPLLCIGVQSQYKSKENCVFQGDEDTYSFYQRGDVVLGGIFPLHSSPVSSLFSFRTKPKPTSYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPEKGSGQSCEDIQMQPSPVIVGDAASGVSMTVLRTLGSFKIPLVSYFASCSCLSNKREFPAFMRTMPSDLFQIKALVKLINYFQWTWVGLIGVNSDYAHFAIQLFLKESEQFNICPAYVHFYPVVLMEDALEELVNILKASSATVIINFSGESELHSILKECRRQNVTHLQWIASEAWATSKSLWEEFGDLLKGTLGFAIHRADIPHLGSYLKEIRPQTSHFLSEFWEETFRCRLNGSLNTHAHGEQAQNWPACNGSENLDNVYTTYSDVSQLRVSYNVYKAVYLIAHALHDMSTCVPGKGPFQNGTCGSLYQIQPWQLLYYMKQANFTILGEEVRFDENGDPIASYDLMNWQRGSDSSLQLVRVGFYDASLEDDKDLVVEESVIMWHRAEKVCAIPRITRYWSLSLFFLQLYFMILTGLNKMEYCNFKWKCNIGFIMH", "length": 571, "header": "tr|A0A8M9PPM5-1|A0A8M9PPM5_DANRE Isoform 1 of Extracellular calcium-sensing receptor OS=Danio rerio OX=7955 GN=olfcx3 PE=4 SV=3 CANONICAL=A0A8M9PPM5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100148278", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148278", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPM5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 104, "end_pos": 106, "annotation": "n_glycosylation_sequon" }, { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 368, "end_pos": 370, "annotation": "n_glycosylation_sequon" }, { "start_pos": 387, "end_pos": 389, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PPM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPM5" }, { "id": "PF01094", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Receptor ligand binding region", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 486, "start_aa": "Trp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 104, "end_pos": 106 }, { "start_pos": 280, "end_pos": 282 }, { "start_pos": 298, "end_pos": 300 }, { "start_pos": 368, "end_pos": 370 }, { "start_pos": 387, "end_pos": 389 }, { "start_pos": 437, "end_pos": 439 }, { "start_pos": 459, "end_pos": 461 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPQ7-1", "uniprot_ac": "A0A8M9PPQ7", "uniprot_id": "A0A8M9PPQ7_DANRE", "mass": { "chemical_mass": 103574.0, "monoisotopic_mass": 103574.0 }, "refseq": {}, "gene_names": [ { "name": "LOC110438053", "type": "recommended", "evidence": [ { "id": "A0A8M9PPQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PPQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7/entry#names_and_taxonomy" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110438053", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7", "locus": {} } ], "crossref": [ { "id": "A0A8M9PPQ7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PPQ7", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15489", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15489", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110438053", "url": "https://www.ncbi.nlm.nih.gov/gene/110438053", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001965", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001965", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019786", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019786", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110438053", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438053", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PPQ7", "url": "https://www.orthodb.org/?gene=A0A8M9PPQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02902", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02902", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323170", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323170", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PPQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HP65", "url": "https://www.uniprot.org/uniprotkb/A0AC58HP65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HP65-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HP65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HP92", "url": "https://www.uniprot.org/uniprotkb/A0AC58HP92", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HP92-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HP92-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLSCTLSAPGHCYLSSGQRFPTWNIFYIAYFFLTEANKHIGFFTLRKKSWQHNMASLCHLDPETEMDYEETHCDTENLEMQTDSQQIFMDSDIGSKHTYSESNTDSQLLSGNISESLSKTALKMICSEYHKREANPSNIHEELHLIQRILRVCDPSNCKLPGYIQNLSMEYFSLHLYTERAICILQHHLRSKSPVSLYLDGTGGVVSKIPNQPKRVLYYALVLPGKDGAAPPLPICELVSNNHSVPAITYWLMLFELHLSNYTELNIHHIETAYSWALMLSVLQAFNKENISSYLDRAYKFCMGQIPWHEMKSYSVLHICSAQILKAFRQTVLKQTDDKGLGDFVTYAFAGLQYATNMTEARIVFHALCVLLTSPQNTSLVKESLALLERVISNAKDDPLEENMEHKDREIYKGEERRDALTITGRSPFFAYFLQVMQEVKEQVASDEITLAKEDNPYFCPGIITILFHTYLGIFPLWSGVLLAELRRNESKEQDVVSDKLPKTRDTNCHVGNWFGIVKHSILHKGKKLKPGTFIRKMHQSLQARYKEHIIQHKLPQEILFQPQPPTTLDQSQETCMKEKEHASSTKSEFYSVPQNVSAPKKRLLKVEAQTDESGPPVKIFKLWKQSSTQLIVAIVRCPNQKLEFLLHHQDFQSLFPHSWITGEAIECYIRAVLNMKGANLYQLSHYTAGIILSGNEDQMACQGLKKVNFEQYDGIITFTNINNHHWRFVFLHAETDSLFILDPLRGVNEMRAAQDACHKFGAYFHMRRQNYGRQDLVDIKWKPSTIEHSFQEDDSSCGVFIMLMAKQVVEQFPKIPENIDITPSKEMMCEYRKNLAEEILLASVSTAEYCSVCGKHNDQSQDECIWIQCKVCQRWFHLYCLRMILPPEEQPWICELCL", "length": 899, "header": "tr|A0A8M9PPQ7-1|A0A8M9PPQ7_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110438053 PE=3 SV=3 CANONICAL=A0A8M9PPQ7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PPQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7/entry#A0A8M9PPQ7-1", "sequence": { "sequence": "MLSCTLSAPGHCYLSSGQRFPTWNIFYIAYFFLTEANKHIGFFTLRKKSWQHNMASLCHLDPETEMDYEETHCDTENLEMQTDSQQIFMDSDIGSKHTYSESNTDSQLLSGNISESLSKTALKMICSEYHKREANPSNIHEELHLIQRILRVCDPSNCKLPGYIQNLSMEYFSLHLYTERAICILQHHLRSKSPVSLYLDGTGGVVSKIPNQPKRVLYYALVLPGKDGAAPPLPICELVSNNHSVPAITYWLMLFELHLSNYTELNIHHIETAYSWALMLSVLQAFNKENISSYLDRAYKFCMGQIPWHEMKSYSVLHICSAQILKAFRQTVLKQTDDKGLGDFVTYAFAGLQYATNMTEARIVFHALCVLLTSPQNTSLVKESLALLERVISNAKDDPLEENMEHKDREIYKGEERRDALTITGRSPFFAYFLQVMQEVKEQVASDEITLAKEDNPYFCPGIITILFHTYLGIFPLWSGVLLAELRRNESKEQDVVSDKLPKTRDTNCHVGNWFGIVKHSILHKGKKLKPGTFIRKMHQSLQARYKEHIIQHKLPQEILFQPQPPTTLDQSQETCMKEKEHASSTKSEFYSVPQNVSAPKKRLLKVEAQTDESGPPVKIFKLWKQSSTQLIVAIVRCPNQKLEFLLHHQDFQSLFPHSWITGEAIECYIRAVLNMKGANLYQLSHYTAGIILSGNEDQMACQGLKKVNFEQYDGIITFTNINNHHWRFVFLHAETDSLFILDPLRGVNEMRAAQDACHKFGAYFHMRRQNYGRQDLVDIKWKPSTIEHSFQEDDSSCGVFIMLMAKQVVEQFPKIPENIDITPSKEMMCEYRKNLAEEILLASVSTAEYCSVCGKHNDQSQDECIWIQCKVCQRWFHLYCLRMILPPEEQPWICELCL", "length": 899, "header": "tr|A0A8M9PPQ7-1|A0A8M9PPQ7_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC110438053 PE=3 SV=3 CANONICAL=A0A8M9PPQ7-1" }, "locus": {} }, { "isoform_ac": "A0AC58HP65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7/entry#A0AC58HP65-1", "sequence": { "sequence": "MLFELHLSNYTELNIHHIETAYSWALMLSVLQAFNKENISSYLDRAYKFCMGQIPWHEMKSYSVLHICSAQILKAFRQTVLKQTDDKGLGDFVTYAFAGLQYATNMTEARIVFHALCVLLTSPQNTSLVKESLALLERVISNAKDDPLEENMEHKDREIYKGEERRDALTITGRSPFFAYFLQVMQEVKEQVASDEITLAKEDNPYFCPGIITILFHTYLGIFPLWSGVLLAELRRNESKEQDVVSDKLPKTRDTNCHVGNWFGIVKHSILHKGKKLKPGTFIRKMHQSLQARYKEHIIQHKLPQEILFQPQPPTTLDQSQETCMKEKEHASSTKSEFYSVPQNVSAPKKRLLKVEAQTDESGPPVKIFKLWKQSSTQLIVAIVRCPNQKLEFLLHHQDFQSLFPHSWITGEAIECYIRAVLNMKGANLYQLSHYTAGIILSGNEDQMACQGLKKVNFEQYDGIITFTNINNHHWRFVFLHAETDSLFILDPLRGVNEMRAAQDACHKFGAYFHMRRQNYGRQDLVDIKWKPSTIEHSFQEDDSSCGVFIMLMAKQVVEQFPKIPENIDITPSKEMMCEYRKNLAEEILLASVSTAEYCSVCGKHNDQSQDECIWIQCKVCQRWFHLYCLRMILPPEEQPWICELCL", "length": 647, "header": "tr|A0AC58HP65-1|A0AC58HP65_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=LOC110438053 PE=3 SV=1 CANONICAL=A0A8M9PPQ7-1" }, "locus": {} }, { "isoform_ac": "A0AC58HP92-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7/entry#A0AC58HP92-1", "sequence": { "sequence": 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rerio OX=7955 GN=LOC110438053 PE=3 SV=1 CANONICAL=A0A8M9PPQ7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110438053", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110438053", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7" } ], "pmid": "" }, { "name": "cysteine-type peptidase activity", "id": "GO:0008234", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008234", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 166, "end_pos": 168, "annotation": "n_glycosylation_sequon" }, { "start_pos": 242, "end_pos": 244, "annotation": "n_glycosylation_sequon" }, { "start_pos": 261, "end_pos": 263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 290, "end_pos": 292, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 377, "end_pos": 379, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 596, "end_pos": 598, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PPQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7" }, { "id": "PS50016", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50016" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PHD-type", "eco_id": "ECO_0000259", "start_pos": 848, "end_pos": 899, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PPQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPQ7" }, { "id": "PS50600", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50600" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like protease family profile", "eco_id": "ECO_0000259", "start_pos": 645, "end_pos": 809, "start_aa": "Phe", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 112, "end_pos": 114 }, { "start_pos": 166, "end_pos": 168 }, { "start_pos": 242, "end_pos": 244 }, { "start_pos": 261, "end_pos": 263 }, { "start_pos": 290, "end_pos": 292 }, { "start_pos": 357, "end_pos": 359 }, { "start_pos": 377, "end_pos": 379 }, { "start_pos": 489, "end_pos": 491 }, { "start_pos": 596, "end_pos": 598 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPR6-1", "uniprot_ac": "A0A8M9PPR6", "uniprot_id": "A0A8M9PPR6_DANRE", "mass": { "chemical_mass": 16474.0, "monoisotopic_mass": 16474.0 }, "refseq": { "ac": "XP_003200563", "name": "transmembrane protein 170B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200563" }, "gene_names": [ { "name": "tmem170b", "type": "recommended", "evidence": [ { "id": "A0A8M9PPR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPR6" } ] }, { "name": "tmem170b", "type": "synonym", "evidence": [ { "id": "XP_003200563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200563" } ] } ], "protein_names": [ { "name": "Transmembrane protein 170B", "type": "synonym", "evidence": [ { "id": "A0A8M9PPR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPR6/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 170B", "type": "synonym", "evidence": [ { "id": "XP_003200563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200563" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003200563.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003200563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200563" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPR6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPR6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmem170b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPR6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-331", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-331", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100001035", "url": "https://www.ncbi.nlm.nih.gov/gene/100001035", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100001035", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001035", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VEMWYHI", "url": "https://omabrowser.org/oma/group/VEMWYHI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PPR6", "url": "https://www.orthodb.org/?gene=A0A8M9PPR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22779", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22779", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22779:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22779:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10190", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10190", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003200563", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PPR6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPR6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-331", "url": "https://zfin.org/ZDB-GENE-070705-331", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MCPPSSGRFLSRRAALQPPGANMNKDYSINLSVQQVLSLWVQGEATLKHFTEMWYWVFLWCLFSSLFVHSAVGLLMCVTLQRHKRGRLITLVLISVGFLASLGGGVITSAAVAVVYRVAGKDMAPLEALVYGVGQTALTVIISFSRILATL", "length": 151, "header": "tr|A0A8M9PPR6-1|A0A8M9PPR6_DANRE Isoform 1 of Transmembrane protein 170B OS=Danio rerio OX=7955 GN=tmem170b PE=3 SV=1 CANONICAL=A0A8M9PPR6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PPR6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPR6/entry#A0A8M9PPR6-1", "sequence": { "sequence": "MCPPSSGRFLSRRAALQPPGANMNKDYSINLSVQQVLSLWVQGEATLKHFTEMWYWVFLWCLFSSLFVHSAVGLLMCVTLQRHKRGRLITLVLISVGFLASLGGGVITSAAVAVVYRVAGKDMAPLEALVYGVGQTALTVIISFSRILATL", "length": 151, "header": "tr|A0A8M9PPR6-1|A0A8M9PPR6_DANRE Isoform 1 of Transmembrane protein 170B OS=Danio rerio OX=7955 GN=tmem170b PE=3 SV=1 CANONICAL=A0A8M9PPR6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100001035", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001035", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P86050-1", "protein_name": "Transmembrane protein 170B", "gene_name": "Tmem170b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRAEGADHSMINLSVQQVLSLWAHGTVLRNLTEMWYWIFLWALFSSLFVHGAAGVLMFVMLQRHRQGRVISIIAVSIGFLASVTGAMITSAAVAGIYRVAGKNMAPLEALVWGVGQTVLTLIISFSRILATL", "length": 132 }, "evidence": [ { "id": "RGD:1561506", "url": "https://alliancegenome.org/gene/RGD:1561506#orthology", "database": "AGR" }, { "id": "MGI:3647046", "url": "https://alliancegenome.org/gene/MGI:3647046#orthology", "database": "AGR" }, { "id": "HGNC:34244", "url": "https://alliancegenome.org/gene/HGNC:34244#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-331", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-331#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5T4T1-1", "protein_name": "Transmembrane protein 170B", "gene_name": "TMEM170B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKAEGGDHSMINLSVQQVLSLWAHGTVLRNLTEMWYWIFLWALFSSLFVHGAAGVLMFVMLQRHRQGRVISVIAVSIGFLASVTGAMITSAAVAGIYRVAGKNMAPLEALVWGVGQTVLTLIISFSRILATL", "length": 132 }, "evidence": [ { "id": "RGD:1561506", "url": "https://alliancegenome.org/gene/RGD:1561506#orthology", "database": "AGR" }, { "id": "MGI:3647046", "url": "https://alliancegenome.org/gene/MGI:3647046#orthology", "database": "AGR" }, { "id": "HGNC:34244", "url": "https://alliancegenome.org/gene/HGNC:34244#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-331", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-331#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TQ79-1", "protein_name": "Transmembrane protein 170B", "gene_name": "Tmem170b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRAEGADHSMINLSVQQVLSLWAHGTVLRNLTEMWYWIFLWALFSSLFVHGAAGVLMFVMLQRHRQGRVLSIIAVSIGFLASVTGAMITSAAVAGIYRVAGKNMAPLEALVWGVGQTVLTLIISFSRILATL", "length": 132 }, "evidence": [ { "id": "RGD:1561506", "url": "https://alliancegenome.org/gene/RGD:1561506#orthology", "database": "AGR" }, { "id": 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"MSKRKREDEDAASEISSASPGSSCVSVKSDQSMKKNLPDFSDASVTSDLSISKTINQRSASPEFSVLSMTSNRSIGQPENFSDEPVTFDSVLSDALDKPDYEKLHRIKDQHKTSMKNKYERLFEGLKLDETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHRASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFHVFYYHVNTTMDGLRNFASVENLIKGAVDKAIESENGHLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLFREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCGIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTRQKLNWDHGGHFRITPGLRKYACFLTLDPNTAHNQLILSEDKRKVTHVKDPQQYTDYPEKFVHQEQVLCKETLTGRCYWEVEWSGEGTDIAVAYKGIRRKAGSDCWFGYSEKSWSLFYTGNGFNVWHNNKSQIIPAPSPLSNRVGVYLDTESGSLSFYSVSDTHTLTHLHTFNTTFTEPLYAGFRVFDSSLSLCNI", "length": 993, "header": "tr|A0A8M9PPT2-1|A0A8M9PPT2_DANRE Isoform 1 of Protein NLRC3 OS=Danio rerio OX=7955 GN=si:ch211-15j1.5 PE=4 SV=1 CANONICAL=A0A8M9PPT2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PPT2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPT2/entry#A0A8M9PPT2-1", "sequence": { "sequence": "MSKRKREDEDAASEISSASPGSSCVSVKSDQSMKKNLPDFSDASVTSDLSISKTINQRSASPEFSVLSMTSNRSIGQPENFSDEPVTFDSVLSDALDKPDYEKLHRIKDQHKTSMKNKYERLFEGLKLDETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHRASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFHVFYYHVNTTMDGLRNFASVENLIKGAVDKAIESENGHLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLFREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCGIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTRQKLNWDHGGHFRITPGLRKYACFLTLDPNTAHNQLILSEDKRKVTHVKDPQQYTDYPEKFVHQEQVLCKETLTGRCYWEVEWSGEGTDIAVAYKGIRRKAGSDCWFGYSEKSWSLFYTGNGFNVWHNNKSQIIPAPSPLSNRVGVYLDTESGSLSFYSVSDTHTLTHLHTFNTTFTEPLYAGFRVFDSSLSLCNI", "length": 993, "header": "tr|A0A8M9PPT2-1|A0A8M9PPT2_DANRE Isoform 1 of Protein NLRC3 OS=Danio rerio OX=7955 GN=si:ch211-15j1.5 PE=4 SV=1 CANONICAL=A0A8M9PPT2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 812, "start_aa": "Thr", "end_pos": 812, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr812", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100148489", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148489", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JW23-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPATAKDALHRLSTYLEELEAGELKKFKLYLGIAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGEDLVRVTPSNGLCSLESQSTCLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGPWCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTSRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFTAMYCALHGREAVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAEDGPPEPPGAQTQSTHSQERNILPDIYSAYLSATICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIANRNLIRLDLSGNSIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSNNSHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVNTCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGISQTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFGMDLNKVTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1PS14-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:dkey-222h21.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNMLQRIKNQHKTSLKNKYERLFEGIEVKETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPENLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGIDVSDASVYSGICTEILKEESVIQQRKVYSFIHLSFQEFLAAFHVFYHHITCSTEASLDSLHDLQKRIINKSTESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKRSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELKLQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITPGLRKYACVLTLDPNTAHTHLVLSEKNRQARNVTDPQPYPDHPDRFKNNEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYSCDTIYTVWHNNKSADIIAPSACTNRVGVYVDVPSGSLSFYSVTDTHTLTLIHTFNTTFTEELYTGFGIYPEASVSLCQI", "length": 892 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3ANC0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch73-168d20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSRKRRSSSPESSCVSIKSDASMDNPPTLRLGESPAKHRRSSSLGSSCVSMKSDASMDNPPTLRLGESPAKHRRSSSPESSCVSMKSDASMDNPPTLRLGESPAKHSDNQKRSQSNKGQKQLDAIFKDLEETNIDEMRKVLRRFKMLLSPDYSVRDEEEEEGQRQINEAFLKITLHALQKMNQTDLASKLQTKLISVSQQQLKSRLKQRFERFTEGVSNRGNTKLLNDIYTEVYITEGGAGNIDDEHEVRQIETSSSRFPEIPIRCCDIFKSLLGQDKAIRTVLTKGVAGIGKTASVQKFILDWAEGKANQDVHFIFPLPFRDLNLIKEKRMSLMELLCCFCPELKPIDYNNFKTVFIYDGLDEWRLPLDFRNNEILWDMNKVASVDALLTNLLQGNLLPSAVHWITTRPAAACQIPAEFIDRVTEVRGFKDLQRAEYFWKRIKDQNLANKIITHIQSSRSLHIMCRIPVFCWISATVLEKIFGEANSADIPKTLTQMFIHLLIVQTNLKTQKYDRECDVNLEKARKSILSLAKLAFEQLEKGNLIFYEEDLKQCGIDVREASVCSGVCTQIFREEFGLQLQKVFSFVHLSVQEFLAALFKFLSFAEENNKSSMTQFMKNEVDRALQSPNGHLDLFLRFLLGLSLDSNQTLLQGLFTPLDTSHSRDETIEYIKSKIRENPSPERSINLFYCLNELNDHSLVQEVQTYLTSTRSHRLSGVKLSPALWSALVFVLLNSTKDLDEFELRQYDFTEECLLRLLPVVKASRKADLKGGNLTDQICSALASALSSSSCCLRELDLSENRLQLSGIRLFSAGLKSPNCKLEILKLSNCSIREEGCASLVSALLSNPSHLRELNLNSNQPGYSTVKLLSDLLENPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLNGSNIREKDCAAFISSLLSNPFHLRELSLSWNKPGDSGVKLLSDLLKDSRCKLEKLELECCSIIEEGCAALALALVSNPSHLRELNLNNNEPGDLGVNLLSFLLKNPQCKLEKLELEYCCIGAKSCASLASAFVSNPSHLRELNLNWNTPEYPAVKLLSDYLKDPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLEYCCIGEEGCAALVSGLKSNPSHLRELNLNRNEPGNLGAKMLSDLLKDPLFELEKLELDDCSIENNGFADLVSGLKSNPSNIRELNLNSNKFIFSGLNLLCDLLRDQQCKLRKLQLECCNIDEEGCAALALALISNPSHLRELNLNYNNPGGLGVKLLSVLLKNPHCKLEKLELSHCSISENYLAALNSALSSNPAHLRELNLNYNENTRQ", "length": 1388 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQ59-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKIFQNLTAESGKGIRDYVVQIRFCFIMDDTQISRDENVSPGCSSVHQKRSDPEPSCVSMRSDWSMDPPISFKSKDTPPDFSSVHQKSTESEPSCVSMRSDDESVDQPLHVRSGDTETDLSHEALNTFRSDLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIIPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLMNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHLLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDGFEEIKKPSLWSKVKDLLYLNSSQLVSLSELHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQIILQRLMILKSRSIQINKTVEYIKMKIRTIDSPEKFINLFHCLNELGDHSLVEEIQQYLKSGRINRAKLSESQWSAVAFVLLTSEKKLEEFHINEFVGETEKIFIFMKLLPVIRECRSVQLNNCGLTDEGCAALASALRSNPEHLRELNLSGNRLGDSVTLLSALLEDPRCNLEILWLSYCGLTDEGCAALASALRLNPEHLRELNLSHNNISKSTVKLLSDLKHNPHNKLETLYI", "length": 837 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YSM0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch211-181d7.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSHKQTLKYFSPVCSSVQQERSDSAEPSSVSVKSHWSIDPPPQMTERRDSLSLALQERSDSPEPSHVSMKSDWSIDPPPQMKEENRSLVQQERSPKSSCVSMKRDWSIDPPPQMNDEDGQKRLSLVQQERSDSAEPSLVSMKSDWSIDPPPQMKDGDRQKSLSLVQQERSDSPEPSHVTMKSNWSIDPPPQMTDRRDSLRQIPRPRPGAEEPISKKMKYDESVIKSQECMENPSLIFSHEVNTFRVNLLKKFQCLYEGMVTQDNPALLNEIYTELYITESESGEISNEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPETKEIDIFSDKYKILFIFDGLDECRLLLNFKSNEILQHVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLMAQINTKDMKYTGKKDKDMIFKLGKLAYEQLERGNVIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFIHLSVQEHLAALYVHLLFTNHNRNVFEQMTKKTSKTLDILDCFHSNSPENVLLSELHQKAVDEALQSKNGHLDLFLRFLLGLSLESNQILLQELMIKFRSSSDSSEKTVEYIKKRINNICLPEKSINLFYCLNELGDHSLVKEIQQYMDYGTLAETKISCGQWSALVFILLTVEQAMDVFELNKFIGLKKSSDEVLRKLLPVIKKSRSAIMDDCNITAEGCAYLASALGSNPSYLRELDLSANKLQDSGIKKLSKGLQDSHCKLEKLNLYHCGVTNEGCAALASALKSNPEHLRDLNLSENKIGNLGLTCLSEILKNSLCKLEILRLCQCGITDCTDLASALISNPEHLRELELSLNKIGDSGVTALCAAFEDPRFKLEKLGLSGCGLTDEGCAALTSALRSNHEHLRDLDLSGNKVDKEVKGSILQRILEKLNNIQILSV", "length": 1068 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YU37-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch73-24k9.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDNQTFSDAPVCSNESNPEFEPSCVSMKSDQSMDPPMKFKEGHTSADLSDRLNPPGSSCVSMKSDWSMDRPIQFKEEHSSADLSNKSNPGEPSCVSSKSDQSMGPPINVMEEHSAADLRLDPHLKQNGLRSNLLRKFQCLYEGTAMQGDPTLLNEIYTELYITESDSGEINNKHELRQIETRSRRSATEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEEKENQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEQFKVLFIFDGLDECRVSLDFKCDVKLHDVSESASVDVLLTNLIMGNLLPSALIWITSRPAAADLIPSEFVHRVTEIRGFNDPQKEEYFRKRIRDQFLADIIIINLKSSRSLHIMCHIPVFCWISATVLEKIFSQAQSGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEVRDEDMILKLGKLAFEQLVKGNLIFYEEDLRECGLDVTEASVYSGLCTQIFREEFGFYQGKVFCFVHLSIQEHLAALYAHHSLTNKNRNVFKQTKPSLLSKVLNQKKHDSLSVLHQRAVKEASQSKNGHLDLFLRFLLGLSLESSGTLLRELLTQTGSCSYNKEETVQYIKQKIRENRSPERSINLFHCLNELGEDSLMQEIQDYLSSGEIKETKLSSSQWSALVYVLLTSEKKMDFFDLSKFIGPQLRADVVLQKLLPVVKESRSVRLGDCKVTDKVCAALASALRLNSSHLTQLDLIGNKLGDSGVKLLSDGLKDPHCKLKNLMMRDCGVTDEGCAALASALRSNSTHLTELNLNENNLGDAGVKRLSDGLKGPHCKLEILRLWRCGVRDEGCAALASALSSNSTHLKELELSDNKLGDSGVKLLSDALKDPHCKLEKLRLNGCGVREQGCVSLALALRFNPSSHLTELDLTSNELGKSGVKLLSDLRDDPRYKLRHLACDMFGRIIVSSGGGRLDELLPTTSTET", "length": 978 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkey-165e24.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHRVRSGSCVSSSVSLKSDCSKEDPPKFSEKTPSSAQSVRSGLCVSSFVSLKSDCSKEDPPKFSEKTPSSAQSDEDELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNELEKFKQILQEENRQEFVKDYNENRSRITEAALDLTLFFLREMKQDHAADTLQDELLFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAVSRRHQSLETQVEFKHLFKAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQLFPETKGLNLTRSTQFKVLFILDGLDECRLPPNFAGNEMCCDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILNLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSQGKLAFQQLERNNVIFYESDLNDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEGIIAYIKQKLEGNLSPERSINLFYCLSELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELWKFQRSDECLIRLSAIIKNSKRALLQSCNLTVQSCKSLSSILQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLATCNLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSEHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDTLNLDHVGDMRITAGPRKYVCFLTLDPNTANTQLKLSKENRKVKHVREDLRIMRKDRRYPYHPDRFDPVFQVLCRESVCGRCYWEIDWSGDHGVFISVSYKSIRRKRGDACEFGCNAQSWSLLCLSSRFTFRHNNTHTHVPVKPLSRRIGVFVDHSAGTLIFYNIYKDTMSLIHSVQTTFTEPLCPGFGFYSGSSVKLS", "length": 1137 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1F5-1", "protein_name": "Protein NLRC3", "gene_name": "si:dkey-23k10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METEGPDSPEPSCVSLRSDHSKAHHVLFKDEDPFEYSSGQTGRSSPTPSHVSLASNMSINQPLEFKSCSNTLLLKEIQEAIQSVLRIRFQCLHEGLSKHSVLIPLNDIYTELYITEGEGGELNNEHEIRWIETACRRALTEDRPVNLNDIFKPLHGQDRPIRTVLTKGVAGIGKTVSVQKFIIDWAEGEANQDIWFIFPLPFRELNLLKDQSFSLKGLLQYFMNIELDISLHEGKIMFIFDGLDECRLPLDFHNNVKLCDVTESASVDVLLTNIIRGNLLPSSLIWITSRPAAADVVPSKCIHRVTEVRGFSDPQKEEYIRKKVSDQTLSDRIISHLKSSRSLYIMCHIPVFCWISATVLKKMLSEAESAEIPNTLTQMYTQFLMLQLRIKNEKAYDKKSSDIDIVLKLGELAFQQLEKLNLIFYKEDLREYGIDEQEASVYSGLFREESGMFQGKVYSFVHLSVQEHLAALYVYLYFVNENINKLNQPNFLTSILKCVPTVFDVYQTAVKKALQSTSGHLDLFLRFLLGFSLESNQNLLGDLQVQTESSSDSREQIVGFIKEKIKESPPPEKMINLFHCLNELNDHSLVEEIQDFLQSESRINMKLTASQWSAMVFVLLTSGQKLDVFDLNKYIGTYILPDESLQRLQPVLAASRTAKLCEHNLTKRGYSVLVSVLTSKTSCLRELNLTRSAVNDSGLKLLCSGLENPQCKLETLRLEFCGVSDKGCDFLASALRSNPSHLKALDLSGNTLNFTGLKNLLAEFQKPHCKLQRLCLRLCGLTDVGCDALASVLRSDPSHLTELNLSGNKLGDLGMKLLAGGLQNPHCKLQILRLGDCSITHEGCAALASALRSNPSHLRELDLSGNKLNNAGVQILSGELENPDCNLEILRLENCDVGEEGCAALAEALKSNPLTLKELDLCWNKLGNSGVQRLCTSLENPNCTLGVLRLTGCNISENGCAALASVLRSNPSYLRDLDLSHNDLRSSGVRLLSSALEKPDCKLEILRLEYCKITDDGCAVLASALKSNPSHLRELYLYMNSFNLTASGRQLLSKIKDDPHYKLQTLHYESHFFC", "length": 1074 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z5L8-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch211-207e19.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKDFNENRSRITDAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTDHEIRQIEAASRRHQSLEIQVECKHLFEAAEQHEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETEGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVDKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKKQGWFFIQISKNKGMIDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKGEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSADLSPAQWSALVFVLLTSEEELEVFELQKFQRSDECLIRLSAVIKTSKRALLQGCYLTVRSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLQFCNLTVQCCESLSSALQSSNCVLRELDLSINDLQDSGVKKLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKYVCFLTLDPNTAHTELILSEENREVKSVRENQPYPDHPDRFDYYHQVLCRESVCGRCYWEIDWSGDGVVCISVSYKSIRRKGGGDECVFGYNAQSWSLRCDSSRFKFWHNNTHTDLPVEALSSRIGVFVDHSAGILIFYNIYRDTMSLIHSVQTTFTEPLCAGFRVYYPGSSVKLS", "length": 995 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PCI8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTQTTIEKDYSPRFSLVHQKRSEPSCVSIRRDQSVAHPIDFKSEDTQTHLSSVHQERLDPEPSCVSIRSDRSVAHPIDFKSKNTHLSSVHQERSEPEPSCVSIRSDRSVAHPIDFKSEDTQTHLSTFHQKRKEADPSCVSMRSDTFMNQPINIKIGETQNDLKQNLLNTFRSNLLKKFECLYEGTAVQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQNKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSEKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCLNNNRNEFEQISKQSLWSKVRDHFHFNSSKLVSISKLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQGLMKLKIRSIQNNETVEYIKKKIRKINFPEKFINLFHCLNELGDHSLVEEIQQFLKSGGMNEAKLSSSQWSAVVFVLLTSEKKLEKFDINEFAARNNNTEQLFIFKKLQPVIRQCRSVQLSYCGLTDEGCAALASALRSNPEHLRDLYLSGNKLGDSVSLLSGVLEDPHCKLETLWLSDCGLTSKDSAALASALRSNPEHLRVLDLSWNRLGDSVTLLSAVLEDPHCKLETLLLRDCGLTDEGCAALASALRSNPEHLKHLDLSWSNLGDSVTLLSAVLEDPRCKLEKLGLSNCGLAEEGCAALASALRSNPEHLRGLNLSVNNLGDSVTLLSAVLEDPRCKLEKIKLSYCGLTDEGCAALASALRSNPEHLRDLDLSTNNLGDSVTLLSAILEDPHCKLEKLELKNCGLTDEGCAVLASALRSNPEHLRDLNLSWNNLSNSTKKLLSDLKDDPHNKLETLHTSLSV", "length": 1115 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PLT8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "nlrc8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSMNHPKHFKSGETQNDLGSAHQKRSDPEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQKRSDPEPSCVSMKSDWSMDPPMQFKSKDTPPDLSSVHQERSEPEPSCMSMNSDLPLDPPIRYKSGETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQSLWSKTKFMFKTVALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLKLKRRSIKNNKTVEYIKKKIRTIDSPEKSINLFHCLNELGDHSLVEEIQQYLKSGGINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAENNKTEKLVIFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTLLSAVLEDPHCKLEKLWLSYCGVTDEGCAALVSALRSNPEHLRELNLSGNNLGDSVTLLSAVLEDPHCKLEKLRLYYCGLTDEGCAALASALRSNPEHLRDLDLSWNKLGDSVTLLSAVLEDPRCKLEKLELYNCGLTDEGCAALASALRSNPEHLRDLNLSGNKLGDSVTLLSAVLEDPRCKLEKLWLSDCGLTDEGCAALASALRSNPEHLTELDLSWNNLSKSTVRLFSDLKDNPHNKLKTLHI", "length": 1017 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PSD3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrc7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEEQGKMSLSEKHSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKPMSAKSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKQTSAKSVISDSCVSGSVFVKSDCSKDGDLPNFSEETPSSGKSFEHKTSDSDFQTHRKHKGFQDGLLGIFQDLENQIMNYLKHELEKFKKILQKENIIDFVKDFNENRCSIKEAALDLTLYFLREMKQEESADTLEDELIFIHQLKCGLQKKYQCVFEGIAQQGDSRLLKNIYTDLYITQGGSEQVNTEHEVRQIEVASRRHEAQELQVECRHLFEASEQDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQEISFIFPLPFREMNLKEKETLSLMELITQFFPETKGLNLTRRNRFKVLFILDGLDECRLPLNFAGNETCCDVSSPASLDVLLTNLIKGNLLPSALIWITSRPAAASKIPPDCIDRLTEIRGFNDAQKEEYFRKRLTDENQAKEIIDHVKQSKSLFIMCHIPVFCWISATVLQNILQEKRNNDVKHNQADDASKTLQESNTEDTPKTLTQMYTHFLRFQIQQSRRKYNGEYTPDVSWDKDAILSLGKLAFHHLLNNNLIFYDTDLEACGIDVYKASVYSGMCTQIFKEETGIILGTMYCFVHLTLQEFIAALYAHLILDTNKKSVFDQDSKKINESMIDLLKTAVDKALESDNGHLDLFLRFLLGLSLQSNRRILRGLLTPQDQDDQSTEKILQYIKQKFDANLSPERSINLFYCLNELNEQTLVKEIQTHLSKGSLSSADFSSAHWSALAFVLLTSDEEMEEFELQKFHKSDECLIRLSAVIKTCKRALLNDCNLTDRSCSALATVLESDTSLKELNMSNNNLQDSGVKLLCTGLKDMKCELEILRLSDCNITEEGYKALASALRSNPSHLLELDLRGNDPGESGVKELDDLLQDPNCTLKTLRFLSPSAEESCQFVNGVVGKNPLLLKTLNLNDFRSTRNHPFIYEIEDTQVNHLAALLQDKHCRVNMLILGGCSFTDDQWESLTSALKLNPSHLRELILMWNGPGESGVKILSDFLIEPQLKLEKLCLCYCSITEERCEILTSALKSNPSHLRELNLSQNIPGDSGMKNLSDLLMNPQSKLEKLQLCKCSITEEQCVILTSALKSNPSHLRDLNLSLNNLGDSGVKTLSDLLMKPHLKMEKLWLCKCSITEEQCVILASALKSNPSHLRELSLSENNLGDSGVKNLSDLLMKPQFKLEKLHLSHCSITEEQCEILTSALKSNPSHLRELDISKNQIRNTGVNLLCDVLNNSDCKLETLRLNDCGITDVSSLTQCLTNTKALQFLKVLYLRENHIGDSKQELSDVVRDSNCELSVDEFSLPDFGQIKDIKCCIS", "length": 1370 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCS9-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLQKKNEDEDEESASEMSYPPPESSCVSMKSDWSMVYPPDLSDASVTSDPNNSKRKGQHLEFKESSCVSVMSNRSITPPEMKKIGLKSEDNMLEKIKNKHKTSMKHKYERLFEGVKLHENQTLLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVGVSDASVYSGICTEIFKEESVIQQRKVYSFTHLSIQEFLAAFYVFYYHITCSTEACFDSLHDLQRRAVDKAIESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITSGLRKYACFLTLDPITAHTQLQLSEENRKASIVTDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGLVAVAYKGIGRKSGFDCCFGHNEHSWCLYCSDEVYSVWDNNKSVDVFGPSSRTNRVGVYVDVPSGCLSFYSVSDTNTLTHIHTFNTTFTEELYAGFKVYPGSSVSLCPVKPAEVPP", "length": 988 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUW9-1", "protein_name": "NLR family CARD domain-containing protein 3 isoform X1", "gene_name": "si:ch211-196h16.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKGNTGFRVKPPEPSGVSMKSDRSMHHPLKFKGGIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDPMFRPPEPSVSEKSGQSVDPTLKFSVHTCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDIGEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSINLFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQLDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLRLRCCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLCRCGVSDEGCAALVSVLSSNSSNLRELNLTENKVGDSGVKLLSAGLKENSKLEKLWLFICGVSDEGCAALASILRSNSSNLRELDLTGNKVGDSGVKLLSAGLKDPHCKLEKLTLDFCGVSDEGCAALASALRSNSSNLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC", "length": 1041 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32T552-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:ch73-50f9.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSGKHSVRSGSCVSRSVSLKSDESRKGLPPEFSEQPPSSNRSVEYELSDSVDKTHCNRKSFTDHLLRIFQDLESKIFKVLKNELERFRQILQGENTQDFVKGSNENQSSITKSALDLTLLFLREMKQDEVADTLENELLFINRLKSSLKKTYQSVSEGIAQQGDSTLLNNIYTDLYITQGANEQVNTEHEIRQIEAASRCHKSLEIQVECKHLFEAPEQDKQIRTVLTKGVAGIGKSVSVQKFVVDWAEGKANQDISLIFPLPFREMNLKEKEKQSLKDLITQLFPEVKGLNLTRRTRNKVLFILDGLDECRLPLNFAGNETCHDVSAPAYLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLADQNLAMEIIEHIKQSKSLHIMCHIPVFCWISATVLQNVLKETKVKHKACAKTLQESPKTLTQMYTHFLRFQMQQSRQKYDGKNTDGVSWDQNFILSLGKLAYQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKQETGIILGNLYCFLHLSIQEFIAALYGHLYLDIKKKSVFTGQKHKNKGMTHLLKTAVDKALESDNGHLDLYLRFLLGLSLQTNRQLLRGLLTQQDKSDQSKEEIVVYIKQKLEENLSPERAINLLYCLNELNDHSLMKEIQSHLRDGSLSSADLSPAQWSALTFVLLTSEEELDEFDLQKFKKSDECLIRLSAVIKSSKRALLQCCNLTAQSCESLSSALQSSNCVLRELELSNNDLQDSGVKLLSCGLRSLNCPLEILRLQCCNLTAQSCESLSLALQSSTCVLRELDLSNNDLQDSGVKLISNGLKSCKLEILRLSGCMVTETGCGFLSSALSSNPTHLRELDLSYNHPGVSGVKLLCQKLEDPNYTLAKLNVDHAGAKRITAGPRKWISHLTLDPNTANTELSLSAENREATRVIEKQPYPDHPDRFDYHPQVLCRESVCGPCYWEIDWSGDVGACISVSYKSVSSKGNDEFGCNDQSWSLSCYSSRFSYGHNNRWTDLPVKPISRRIGVYVDHRAETLRFYNICGNTVHLVHSVRTTFTQPLYAGFKIYPGSSVKLC", "length": 1099 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TA29-1", "protein_name": "NLR family CARD domain containing 9 isoform X3", "gene_name": "nlrc9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTKISKDEDYSPRFSSVHQERSDLEPSCVSMRSEQSMGSPMHFRSEDTEADLSSVYQKRSDPEPSCVSMRSDWSMDLPYNFRSEDTPTDLSSFHHKRTEAEFSRVSMRSDMFINHPINIKNVEAQCNIRQNLLNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFESAVRLCDISESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPMFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDEFEQIKKQSLWFKVKDLFQLNSLECVSLFSLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQRLMKLKSRSMQTNKTVKYIKMKIWTIDSPEKSINLFHCLNELGDHSLVKEIQQYLKSGRINRAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAGNNENKKQKVFQKLLPVIKQSRSVLLYNCGLTEMDWDNLTSALRSNPSDLRVLNLSRNILGNSVTLLSAVLEDPCSKLEKLWLSDCGLTDEGCAALATALRSNPEHLRELNLSWNNLRDSVTLLSAVLEDPRCKLETLWLSKCGITGKSCAVLASALRSNPEHLRDLDLSGNKLGDSVTLLSAVLEDPHCKLKILWLSDCGLTDEGCAALASALRSNPGQLRVLDLSENKLKNSGVMQLCAVLEDPHCKLDKLGLYDCSLTDEGCVALASALRSNPEHLRELDLSVNKLRDSGIKLLSAVLEDPRCKLEKLWLSNCGLTDEACAALASALRSNPEHLRELNLSKNKLGESDVKLLSDLKDDTHYKLKELNY", "length": 1079 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TJY6-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkeyp-100h4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQQIQETRLKGDTRASQTISSPSSSCSMAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKDCPPVFSGETPSSAQSVEFESADSGDETHRRHKSFTDNLQSIFQNLESKMFTFLKNELEKFKKILQENRQEIVKEFNENRSRITEAALDLTIFFLREMKQDQAADTLVGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVKCKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDDQKQEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGFVLHTMYCFLHLSIQEFIAALYQHLILDNDKTQAEKSRDESMIDLLKAAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEANLSPERSINLFYCLNELNDQSLLKQIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAIIKTSKRALLQGCYLTVPSCESLSSVLQSSNCVLRGLDLSNNDLQDSGVNLLSDGLKSQHCKLETLRLVMCNLTVESCESLSSVLQSSNFVLRELDLSNNDLQDSGVKLLSDGLKTVNCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVELLFEKLADPNYTLDKLNLDHGGHTRITAGPRKNACFLTLDPNTTYAFLILSEENREVKTVREYQLYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDDYVDISVSYKSIMRKGVDPECVFGRNAQSWSLCCDSSSFTFWHNDTDTRLPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLWPGFTVWCQSSVKLC", "length": 1125 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TMV3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like", "gene_name": "si:ch211-197e7.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDWSKEDPPKFSEKTPSSAQSVRSGSCVSSSVSLKSDRSKEHPLPNFREKTPSSAQSVEHELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNEMEKFKKILQEENRQEFVKDYNENRSRITEAALDLTLFFLREIKQDQAADTLQDELFSINQFQCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNNEHEIRQLEAASRRHQSLETQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNKTCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKILFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALENENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDESKKKIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFMLLTSEEELEEFELRKFQRSDECLIRLSAVIKTSKKALLQSCNVTVQSCKSLSKVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLAMCNLTVQCCESLSLALQSSNCVLRELDLSNNDLQDSGVKLLSNRLKSQYCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDKLNLDHGGEKRITAGLHKYVCFLTLDPNTAHIQLILSEENRKVKPVREDMMMMRKDQPYPDHPDRFDGLYPQVLCRESVCGCCYWETDWSGDGGVCISVSYKSIRRKGGVECEFGRNAQSWSLHCSSSRFIFIHNNTETRLPVKRLSKRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRVYSGSSVKLS", "length": 1140 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TPE7-1", "protein_name": "Protein NLRC3 isoform X4", "gene_name": "si:dkey-11n14.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKYSVRSGSSSSVSLKSDWSKDEPPKFSEKSPSSARSVEYELPYSGDKTHRSHKGFTKDLPRIFQNLESKIIRYLKNELEKFKKILQEENRQDFVKHFNENRSIITEAALDLTLFFLREMKQDEAADTLEGELFFINQLKCGLKKKYQNVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTTGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKENQSLKDLITQFFPQTKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTKLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISANVLLNILKENRNTELKHRDNSETLHESPKTLTQMYTHFLRFQIQHSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYDSDLKDCGIDVYKASVYSGMCTQIFWEETGIILGTMYCFLHLSIQEFIAALYQHLFLDSDKKHLSIFRQKSKNKVMTDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQNDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSADLSPAQWSAVAFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQGCNLNVRCCESLSSALQSSNCLLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDTLNLNHGGEKRITAGPRKYVCFFTLDPNTANTRLILSKKNREVKCVRENQSYPRHPDRFDDHPQVLCRESVCGRCYWEIDWSGGNEVCISVTYKSIRRKRGYECRFGYNAQSWSLICSSSRFSFTHNDTHTDLPVKPFSRRIGVFVDHCAGTLIFYNIYRDTMSLIHSVQTTFTEPLIPGFWVYSGSSVKLLKTEERFTQNPLQDQ", "length": 1060 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQ28-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:ch211-226o13.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTHTSGDLDLFTSCSVDGDDQTRDLQQDSLQPEHDELQRAKNQHKTSMKNKYERLFEGINHGETQKFLNRIYTQLYIIEGESEGVNREHDVLQIEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQGVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITARPAAAHQIPSTYIHRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDQEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFHCYLTDKREPVMLLYESKYSDDEDVSDGNEYEDSDVQFLQSSSEFSLCHLLSLAIYKAVMSSNGHLDLFLWFLLGVSLESNQRLFQDLLTHTEESSESIRIITQDIKDKIKTDDDLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSERELSPAHCSTISYMIEMSEEPLDELDFNKLNTSPVGRWRLIPAVRNCRRALLQWSYLSVQYCESLFSALKSSNCVLRELDLSTNDLQDSGVKLLSDGLKSPNCKLETLRLQCCNLTAQSCESLTSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCKLETLRLVMCNLTVQCCESLSLALQSSNCVLRELDLSNNGLQDSGVKLLSDGLKSQHCKLDTLRLVMCNLTVQSSESLSSALQSSNCVLRELDLSTNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGLHKYACFLTLDPNTTYAFLILSEENREVKRVREYQQYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDGCSVCTAVSYKSIRRKGRGAECLFGRNAQSWSLCCSSSSFIFRHNYTRTELPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFTVWCQSSVKLC", "length": 1145 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TTK4-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAMNRLMTDMLEELVEAELKQFTRQLWMGVKPGVDPIPRGKLENKDRQDVVDCMVQHYSKDAGKIAVQALRSIKQNERADRLELNLRKDDDFLGEVLKKHKESIKASVDVFEGKKDNKTDINKVYTELFITEGDMTDVCKEHEVQKFDLALQMPRSEDKPIDCNEIFNLLRGKDKGNVVLTKGIAGIGKTFSVNKFILDWAEGRANLDVDCMFLLPFREINLMIKDGDVSLHKFLLKLFPDITGVETTPFYEKCKLLFIFDGLDESRLDLNFNLSSVDDVHSCASIDGLFTSLIKGRLLRSSLIWVTSRPAAANRIPSYHVGLFTEVRGFTDKQKEEYFRKKVPDEDQASRIISHIRTSRSLYIMCHIPVFCWIIATVLQDILQKNKGEDIPSTLTEMYIHFLLIQMNIKNQKYDEKLIRDRTELLGSNRDMISKLAKLAFEQLKKENVMFYREDLAACGINADEEFTGLCTEIFKKDSVLHELKVYYFIHLSVQEFLAALHVFLCYLELEKDMNLTDSDLMFFLEDSRPKQKELLHVLLRKAIDKAEKSDRGHFDLFLRFLLGISLESNQKLLIGILNETKNSKQSISKTVQYLKQLQNNDKCPDKSINHFFCILELQDRTLYQQIMKYLRSKTNRPKVMSRSNCSALVYVLLMSQEVLDKFNPKLFNKTYAGCRILVPAVRCSRKALFSDCGLTETCFETVALALQLENCPLVELDLSYNYSLEAAVNVMCAGLKSPHCHLESLRLAGCHLGQDSCMQVVSALQSISHRLKELDLSGNDLQDSGLQKLLQGMENTEKRLQVLRLSWCNLTEMSCQQLSTILSSNSVFRELDLSNNDLQDSGVKLLSDGLKSPNCKLKILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHCKLKTLKTDPMGDHLMKPGIVKYAFNLTLNPNTAHVHLLLSDGDRKVTLKEKQPYPDDPERFEEHHQVLSRESLSGRCYWETEWTGQEGTVGVAYESIPRKPDDLLYGRCMLGNNIISWKITCGSRTHVSHAEEDITVKSPSSGSCKRVGVYVDTTAGVLSFYHVFDTLTHLYTFLMPFTQPLYAAFRVDGESVSICPIP", "length": 1114 }, "evidence": [ { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TUF4-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch73-236c18.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHHCGNEEVDREEKEKHGAEHSCVSMKSDQSMRNPIAFTDKAVTFDLRSVASSSSHFETHTVQEKTDKGLQTQIFETEELQRVKDQHKTSMRKKYELLSEGIKVKETGTQLNRIYTQLYIIEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFYVFYYHVNTTMMGLKTFASLQKLLKGAVDDAIESKNGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCRLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRIKPGLKKYACFLTLDPNTAHVQIQLSEGNREARNVKDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYCCDTNYTVWYNNESADIIAPSARTNRVGVYLDVSSGSLSFYTVSDANTLTLIHTFNTTFTEPLYTGFGLYPESSVSLCQI", "length": 969 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58HZJ9-1", "protein_name": "Uncharacterized protein si:ch211-149a19.3 isoform X1", "gene_name": "si:ch211-149a19.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDKEASNDGDFSSRRSHFQSQKSNTSESNPEITPEDLSAKKLIKMFEKRTPDNQSKFNNQKSNTAKSIRSDRSIQNPVKIKEIRTPADLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPKPMPRSIKSDQSTPELDKVDGGHTSTALSSQRSNPPDPKPRSIKSDQSTPEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGIGCQRSNPPDPKPRSIKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPESSLVSLKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSMPEPIKFDGGHTPTGLSETSTNDQFMNKQVKIKRRHTLTGLSKTSINYQFMEKQLKTERRHTSTGLSLNSKLFENLLKSNLLKKFQCVSEGTSILGNPTLLNEIYTELYITESDSGEINNEHELRQIETQSRRSAKEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEKNKNQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEHYKVLFIFDGLDECRVSLDFDSGVKLHDVSESASVDVLLMNLIMGNLLPSALIWITSRPAAADLIPSGFVHRVTEVRGFNDPQKEEYFRKRIRDQSLADTIISHLKSSRSLHIMCHIPVFCWISATVLEKIFSQAERGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEDKDMILKLGKLAFEQLQKGNLIFYEEDLRECGLDLTEAAVYSGLCTQIFREEFGFSQSKVFCFVHLSIQEHLAALYAHHFLTNNCLNKHWKTFNPLSFLHQRAVNEALQSKNGHLDLFLRFLLGLSLEFNQTLLQELLTQTGSCSYNTEETVQFIKQKIREINSPERSINLFHCLNELGDQSLMKEIQNYLRSGEIKETKLSSSQWSALVYVLLTSEQEMEDFDLNQFIGTQNTADEVLQKLQPVVKESRSVQLSGCSVTDKGCAALALVLRSDSSHLRELDLSENNLRDSGVKLLSDGLKDPHCKLEKLRLSDCGVTDEGCAALASALRSNSTHLTELDLSLNNLEDSGVKLLSDGLKDPHCKLEILRLSDCGVTVEGCADLASALRSNSTHLRELDLTLNNLEDSGVNLLSAGLKDPHCKLEKLRLSDCGFTDEGCADLASALRSNSTHLTELDLSLNNFGDSGVKLLSDGLKDPHCKLEKLRLSYCRVRAEGGVALASALRSNPEHLRELDLSENKLGNSGVKMLSELKNDSRYKLDTLKF", "length": 1375 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCK2-1", "protein_name": "Uncharacterized protein si:dkey-26m3.3 isoform X1", "gene_name": "si:dkey-26m3.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGYVFVLSSLCPVFILLQFLLEFLLEIKLFRSIMGNTHAAGDQDLSTECSSVHQKRAEAEPSCVSMKSDASMGVPITFKSENTGPAVSSVHQKRAEAELSCVSMKSDASMNPPIEFKSGNTGPAVSVDRDGQTGDLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEQIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKDNQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPKLEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTEPSSVAVLMRSLLKGDLLPSALIWITSRPAAAHQIPSTYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLDSNQRLFQDLLTHTEESSENIRRITQYIKDEIKRGKHLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELTPAHCSTISYMIEMSEEPLDELDSNKFNTSDVGRRRLIAAVRNCRRALLQRCELTVQCCESLSSALQSSNCVLRELDLSNNDLQDSAVKLLSDGLKSQHCKLETLRLMTCKLTADSCESLSSALQSSNCVLRELDLSNNDLPDSGVKLLSDGLKSQHCKLETLRLQWCKLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLAMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKTVDCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKYVCFLTLDPNTANTRLILSEENREVKHVRENQPYPDHPDRFDGVYQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGVECWFGSNAQSWSLSCSSSNFSFRHNNTRTDLPVKALNRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRIYPGSSVKLS", "length": 1239 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCL0-1", "protein_name": "Uncharacterized protein si:dkey-165o8.1 isoform X1", "gene_name": "si:dkey-165o8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDQSKDHPPYFREETPSSAESVEYESADPGDETHRRHKSFTDNLQSIFQNLESKIIRFLKNELEKFKKILQEENRKEFIKEFIENRSIITEAALDLTLFFLREMKQDQAADTLQDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNKIYTDLYITQGASEQLNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCGDVSSAVSLDVLLTNLIMGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILRLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLDRNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLDIDKKRGWFLIQISKNKSMIDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQFCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKCRTTHTQTHTHTHTHIHTHTHTHTHIHTHTHTHTHTHTRAHTHTHTRGLQQDRANVGPHTYTHTHTHTHTYTYTHTHTHTHTHTHTHTRITAGPRKCRTTHTHTHTYTHTHTHTITHTHLHIHTHTCTHTHTCAHTHTHIHTHTLTHTRTYTHTHTHTLPLTHTHTHTLSHTHTHTHTNIHTHSLTHTNIHTHSLTHTNKHTHSLSHAYTHACMHALSHLHTHTHALTHTHTHTHTHSLTHTHICTHKHTHTLSHSHKHSHTHTHTHTHTHTHTQARAHLHKHTLSHTHTHIHIYTHTYKHTHILSHTHAHTHTHTQARALTQTYSLTHTHTHTHKHTLSHTHTHIHHTHTQIHIHSHKTHTHARTHTLSLSLTHTHTHTHTHTHTHTHTHTHTHTQLWL", "length": 1266 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A523-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWNDACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGRTKMWDRPMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEEEEKRGSQPLDQVQCVFPDPHVACSSRLVNCCLTSSFCRGLFSSLSTNQSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSSQKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTNQNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNCETKRTLEALQEEKPELTVVFEISW", "length": 1035 }, "evidence": [ { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FA88-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "nlrc11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYCNYNMDNTRSSRDEDIYSCTSRESEEVLSNTSYWSLPSYFRHRKFHRSSVHEKISDSSESSRVSLKSDWSMNPPPLLGEERKSSNLNMSSLVSVRSDWSMDPPPLLRAKGKSAVSSGVSDNIDWLVCSPYLRVERKSSALRHKLSLLKKFQCLYEGTAVQGKPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLIKDKKFSLVSLLQTFFTREIHLDMIQNSAVIFIFDGLDECRLPFNFSRNEILLDVTKETSVDVLLTNLIVGNLLPYALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILRLGKLAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLLFTNHNINVFEQMTKSFEGTPLNKSDLQSLTLNMELFEISEPVLTDVAAMCEMDWRVVNEISALHCKAVDEVLQNKNGHLDLFLRFLLGLSVECNQILLQRLTKQRRHLYNDNKTVEYIKKKIRTINSPEKSISLFHCLNELGDHSLVEEIQQYLTSGKIKEFKLSSSQWSAVAFVLLTSEKKLEEFWLKEFVGAETKADHVLQKLLPVVKESRKAELSKCGLTEECCAALASALRSKLSHVRELDLSGNKLGDSGIENLSTGLENLHCKLEILRLRSCGITAKGCTALASALRSNPEQIRQLDLSENNIRDWGVKHLFTELKNPDCKLEILGLRNCGITIEGCAALTSALIINPSHLRELDISRNSLGDTGQELLTSLLNSQHHKLEILLLHKFPMTFTSLPSSHSPEMFPQRFRTHNLKE", "length": 966 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q5R7-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSTARDGLYRLSTYLEELEAGELKKFKLFLGIAEDLSQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGEDLVRVTPNNGLCLFESQSACPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPEPPHTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGPWCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTPRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFAAMYCALNGREAVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWSISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQVVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGSAYSTGMEDDPPEPSGVQTQSTYLQERNMLPDVYSAYLSAAVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISGSACQDLAAAVIANRNLIRLDLSDNSIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLSNNSYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVNTCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGISQTLHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFGMDLNKKTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081031-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081031-11#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M918-1", "protein_name": "NLR family, pyrin domain containing 14", "gene_name": "Nlrp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTEDEEMEDQLSKEEIVSEDKEFDYRTIIKENFFIIWDKTSLLGESATLNCVTTHKDQKLLEHIFDVNIQTSKSPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLSGREISQEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFALCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMTCQTSTALFTYYICSLFPRIAGSSVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQDTECENCYTFTHLQVQEYFAALFYLLRENPEEKDHPLEPFENVHLLLESNHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLTISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVKVDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDPTAEICLEDAAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLNSCYDFSFLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQSNRSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTKTKRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNNKSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNNSNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNNQSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCPNTESGCWWQYF", "length": 990 }, "evidence": [ { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P59046-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "NLRP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQSTCLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELKPSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEGEGGAGPDQDVTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSAGAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIANKNLTRMDLSGNGVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC", "length": 1061 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6B966-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "Nlrp14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTEDDEMEYEASKEETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITPKDQNLLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLNGKEISQVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFALCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVGCVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQDTEYENCYMFTHLHVQEFFAALFYLLRENLEEQDYPSEPFENLYLLLESNHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVRVDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLDTAEMCLEGAAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLNGCQDFTFLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTKSKRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHNRSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNNSNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNNKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECPNTESGCWWNYF", "length": 993 }, "evidence": [ { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081031-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081031-11#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86W24-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "NLRP14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSSSSSFFPDFGLLLYLEELNKEELNTFKLFLKETMEPEHGLTPWNEVKKARREDLANLMKKYYPGEKAWSVSLKIFGKMNLKDLCERAKEEINWSAQTIGPDDAKAGETQEDQEAVLGDGTEYRNRIKEKFCITWDKKSLAGKPEDFHHGIAEKDRKLLEHLFDVDVKTGAQPQIVVLQGAAGVGKTTLVRKAMLDWAEGSLYQQRFKYVFYLNGREINQLKERSFAQLISKDWPSTEGPIEEIMYQPSSLLFIIDSFDELNFAFEEPEFALCEDWTQEHPVSFLMSSLLRKVMLPEASLLVTTRLTTSKRLKQLLKNHHYVELLGMSEDAREEYIYQFFEDKRWAMKVFSSLKSNEMLFSMCQVPLVCWAACTCLKQQMEKGGDVTLTCQTTTALFTCYISSLFTPVDGGSPSLPNQAQLRRLCQVAAKGIWTMTYVFYRENLRRLGLTQSDVSSFMDSNIIQKDAEYENCYVFTHLHVQEFFAAMFYMLKGSWEAGNPSCQPFEDLKSLLQSTSYKDPHLTQMKCFLFGLLNEDRVKQLERTFNCKMSLKIKSKLLQCMEVLGNSDYSPSQLGFLELFHCLYETQDKAFISQAMRCFPKVAINICEKIHLLVSSFCLKHCRCLRTIRLSVTVVFEKKILKTSLPTNTWDGDRITHCWQDLCSVLHTNEHLRELDLYHSNLDKSAMNILHHELRHPNCKLQKLLLKFITFPDGCQDISTSLIHNKNLMHLDLKGSDIGDNGVKSLCEALKHPECKLQTLRLESCNLTVFCCLNISNALIRSQSLIFLNLSTNNLLDDGVQLLCEALRHPKCYLERLSLESCGLTEAGCEYLSLALISNKRLTHLCLADNVLGDGGVKLMSDALQHAQCTLKSLVLRRCHFTSLSSEYLSTSLLHNKSLTHLDLGSNWLQDNGVKLLCDVFRHPSCNLQDLELMGCVLTNACCLDLASVILNNPNLRSLDLGNNDLQDDGVKILCDALRYPNCNIQRLGLEYCGLTSLCCQDLSSALICNKRLIKMNLTQNTLGYEGIVKLYKVLKSPKCKLQVLGLCKEAFDEEAQKLLEAVGVSNPHLIIKPDCNYHNEEDVSWWWCF", "length": 1093 }, "evidence": [ { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R4B8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWNDTCTSHSSMVCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIGRTKMRDSPMSSLKLELLFEPEDGHSEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSDYLQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFFHNSPKEEEEERRGGRPLDQVQCVFPDTHVACSSRLVNCCLTSSFCRGLFSSLSTNRSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSSSQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTNQNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHNHSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNRETKRALEALQEEKPELTIVFEISW", "length": 1033 }, "evidence": [ { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081031-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081031-11#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW", "length": 1036 }, "evidence": [ { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPT2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPT2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 519, "end_pos": 521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 666, "end_pos": 668, "annotation": "n_glycosylation_sequon" }, { "start_pos": 681, "end_pos": 683, "annotation": "n_glycosylation_sequon" }, { "start_pos": 691, "end_pos": 693, "annotation": "n_glycosylation_sequon" }, { "start_pos": 72, "end_pos": 74, "annotation": "n_glycosylation_sequon" }, { "start_pos": 773, "end_pos": 775, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" }, { "start_pos": 926, "end_pos": 928, "annotation": "n_glycosylation_sequon" }, { "start_pos": 970, "end_pos": 972, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PPT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPT2" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 802, "end_pos": 993, "start_aa": "Asn", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PPT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPT2" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 189, "end_pos": 323, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 812 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 519, "end_pos": 521 }, { "start_pos": 666, "end_pos": 668 }, { "start_pos": 681, "end_pos": 683 }, { "start_pos": 691, "end_pos": 693 }, { "start_pos": 72, "end_pos": 74 }, { "start_pos": 773, "end_pos": 775 }, { "start_pos": 80, "end_pos": 82 }, { "start_pos": 926, "end_pos": 928 }, { "start_pos": 970, "end_pos": 972 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPU1-1", "uniprot_ac": "A0A8M9PPU1", "uniprot_id": "A0A8M9PPU1_DANRE", "mass": { "chemical_mass": 224996.0, "monoisotopic_mass": 224996.0 }, "refseq": { "ac": "XP_021323205", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323205" }, "gene_names": [ { "name": "LOC101885430", "type": "recommended", "evidence": [ { "id": "A0A8M9PPU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1" } ] }, { "name": "LOC101885430", "type": "synonym", "evidence": [ { "id": "XP_021323205", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323205" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PPU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323205", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323205" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323205", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323205" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101885430", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1", "locus": {} } ], "crossref": [ { "id": "A0A8M9PPU1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PPU1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01644", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01644", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101885430", "url": "https://www.ncbi.nlm.nih.gov/gene/101885430", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001878", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001878", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR005312", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005312", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008042", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008042", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036397", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036397", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040676", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040676", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043502", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043502", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885430", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885430", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PPU1", "url": "https://www.orthodb.org/?gene=A0A8M9PPU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47331:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47331:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03564", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03564", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05380", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05380", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18701", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18701", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323205", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323205", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PPU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HM25", "url": "https://www.uniprot.org/uniprotkb/A0AC58HM25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HM25-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HM25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HM47", "url": "https://www.uniprot.org/uniprotkb/A0AC58HM47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HM47-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HM47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMTDHGSNLCTPAKVNKQIDNVQNKEVDEEIEVQSEELDTNVRRSTRERTQTDRMLAYQREESHKAESKLMHAYEKWKAEARKARSQLKLDISESELASLIDSLEREKDSVMNAYIRVRSNVTPPTDMRRKIDACDAVTKDIVKIAYERISGVDGGFDNDTVKGHLRELLERDYARSVYGSTVSRISSKSSTPISQPSLNSILMAKRIEAAAELAAKEAEYATVIEEREQREKLRLLEEKQRKELEAQKGEFERLQVMKEVRAARARLEVYDKEETVDTVNQDEGLQQPVSPPTHKPVYLSSVNPTPNISSQGPNADVSQLAQAVQDSITLNRLPMPEPTVFSGDPIHFIEWKASFQSLIDKRHISSGDKLYYLKKYVTGPALKVLDGIFYRNDEEAYKDAWKRLLDRYGQPFIIQRAFREKLACWPKIQSKDSVGLRNFSDFLNSCKDAMPHVKGLEILNDCEENRKLVSKLPDWAAARWNRQTTQTLSETQDFPTFQEFAHFMSVEAEVACNPVTSFHALHVSEPNKEKIYFKGSKPKANVFHTKTVTQHDNSKPTGKVNKPCLFCQNGEHQIHECSKFSARSLEERRQFVKDTRLCYGCLRLGHSAKDCRSRHCCNTCKGRHPTCLHDDSFNRKVRSSAQSPENVHEGVATMSLSVESGCTPVNTSMIVPVWLSTHKDPVSEKLVYALLDTQSDSVFIECAVCKSLKVDSCPVTLKLTTLVGKDSLMSSERISGLRVRGFNSSLIIDLPPAYTKECIPVDRAHIPTMETASHWKHLATLADKIPPLQNCEVGLLIGYNCSRALAPREVILGTENEPYAVRTDLGWSIIGPSLTHFEPQSSAAMCHRVSIKEIPAVTPTDVIKVLESDFKDTEGPTKVKSQEDIMFLRKLEKNIRLNKDSHLEMPLPFRKRPYLPDNKPLAVIRLQHLKRRLMRDQEYREHYVTFMEEVIEKGNAEQVFEEGREGERWYIPHHGVYHSKKPGKLRIVFDCSARYKGTSLNDHLLTGPDLMNSLTGILLRFRQYPVALMCDVEKMFHQFHVDHADRDYLRFLWWRNGDFNSQPQTFRMTVHLFGASSSPGCANYGLKHLAREGERLYPLGSQFIMQDFYMDDGVSSIESTEKAIKLAEEARQLCALGSLRLHKFVSNDKEVLKTIPPSECAVDVTAVDLALTDQPLERALGIYWSLEQDNFKFRITVKDQPATRRGILSIVASLFDPLGFLAPFVLKGKTILQEMCRSGMGWDDNLPADLQSAWEHWKADLVNLEKIEVPRCIVPSGFGRIIRREIHHFSDASMSGYGQCSYLRLENEQGDISCSLLMAKSRVAPLKITTIPRLELAAAVVSVAVNDMLKEEMNLADAETFFWTDSQVVLGYINNEARRFHTFVANRVQRIHRTTTPQQWRYICSDENPADYASRGLSVNNLVTSNWFRGPKVLWERQIPPPMEISKQLPIGDPEVKKVQSLNTQTVQYSCLSDRLTKLSSWSKAIQAVARLIRRVRKDKSHNHSTLAERNDAQCIIIKDLQKQTYAEEITLLRKGKQLPRSNRLYNLDTFVDQDGLLKVGGRLCEASIPNAVKYPVILPKEHQLTKLLIADCHEKMAHQGKGMTINEIRSRGFWITEVNRTVASFVRQCVRCRKLRGPTEEQKMANLPSERIEPSPPFTYSGMDVFGPFITCKGRKSNKRYGLLFTCFCCRAIHIEMLDDMSTDAFINGLRCFIAIRGAVHQIRCDQGSNFIGARNELTKAMEEIDTNRLVTFLAEKQCDFVFNAPHSSHTGGVWERQIRTVRSVLRSTLSQSSGRLDDSSLRTFFYEAMSIVNSRPLTVDSLTDPSSPEPLTPNHLLTLKPTQALPPPGKFVREDVYARKRWRHVQYLAEQFWGRWHKEYVSNITTRQCWHTPRRNMQVGDIVLEKAVDLPRNEWRLARIIEAVTDKDGLVRRVKIQFGDRNLGKDGKRPHKPSVVERPVQKLVLLMEAA", "length": 1973, "header": "tr|A0A8M9PPU1-1|A0A8M9PPU1_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101885430 PE=4 SV=1 CANONICAL=A0A8M9PPU1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PPU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1/entry#A0A8M9PPU1-1", "sequence": { "sequence": "MMTDHGSNLCTPAKVNKQIDNVQNKEVDEEIEVQSEELDTNVRRSTRERTQTDRMLAYQREESHKAESKLMHAYEKWKAEARKARSQLKLDISESELASLIDSLEREKDSVMNAYIRVRSNVTPPTDMRRKIDACDAVTKDIVKIAYERISGVDGGFDNDTVKGHLRELLERDYARSVYGSTVSRISSKSSTPISQPSLNSILMAKRIEAAAELAAKEAEYATVIEEREQREKLRLLEEKQRKELEAQKGEFERLQVMKEVRAARARLEVYDKEETVDTVNQDEGLQQPVSPPTHKPVYLSSVNPTPNISSQGPNADVSQLAQAVQDSITLNRLPMPEPTVFSGDPIHFIEWKASFQSLIDKRHISSGDKLYYLKKYVTGPALKVLDGIFYRNDEEAYKDAWKRLLDRYGQPFIIQRAFREKLACWPKIQSKDSVGLRNFSDFLNSCKDAMPHVKGLEILNDCEENRKLVSKLPDWAAARWNRQTTQTLSETQDFPTFQEFAHFMSVEAEVACNPVTSFHALHVSEPNKEKIYFKGSKPKANVFHTKTVTQHDNSKPTGKVNKPCLFCQNGEHQIHECSKFSARSLEERRQFVKDTRLCYGCLRLGHSAKDCRSRHCCNTCKGRHPTCLHDDSFNRKVRSSAQSPENVHEGVATMSLSVESGCTPVNTSMIVPVWLSTHKDPVSEKLVYALLDTQSDSVFIECAVCKSLKVDSCPVTLKLTTLVGKDSLMSSERISGLRVRGFNSSLIIDLPPAYTKECIPVDRAHIPTMETASHWKHLATLADKIPPLQNCEVGLLIGYNCSRALAPREVILGTENEPYAVRTDLGWSIIGPSLTHFEPQSSAAMCHRVSIKEIPAVTPTDVIKVLESDFKDTEGPTKVKSQEDIMFLRKLEKNIRLNKDSHLEMPLPFRKRPYLPDNKPLAVIRLQHLKRRLMRDQEYREHYVTFMEEVIEKGNAEQVFEEGREGERWYIPHHGVYHSKKPGKLRIVFDCSARYKGTSLNDHLLTGPDLMNSLTGILLRFRQYPVALMCDVEKMFHQFHVDHADRDYLRFLWWRNGDFNSQPQTFRMTVHLFGASSSPGCANYGLKHLAREGERLYPLGSQFIMQDFYMDDGVSSIESTEKAIKLAEEARQLCALGSLRLHKFVSNDKEVLKTIPPSECAVDVTAVDLALTDQPLERALGIYWSLEQDNFKFRITVKDQPATRRGILSIVASLFDPLGFLAPFVLKGKTILQEMCRSGMGWDDNLPADLQSAWEHWKADLVNLEKIEVPRCIVPSGFGRIIRREIHHFSDASMSGYGQCSYLRLENEQGDISCSLLMAKSRVAPLKITTIPRLELAAAVVSVAVNDMLKEEMNLADAETFFWTDSQVVLGYINNEARRFHTFVANRVQRIHRTTTPQQWRYICSDENPADYASRGLSVNNLVTSNWFRGPKVLWERQIPPPMEISKQLPIGDPEVKKVQSLNTQTVQYSCLSDRLTKLSSWSKAIQAVARLIRRVRKDKSHNHSTLAERNDAQCIIIKDLQKQTYAEEITLLRKGKQLPRSNRLYNLDTFVDQDGLLKVGGRLCEASIPNAVKYPVILPKEHQLTKLLIADCHEKMAHQGKGMTINEIRSRGFWITEVNRTVASFVRQCVRCRKLRGPTEEQKMANLPSERIEPSPPFTYSGMDVFGPFITCKGRKSNKRYGLLFTCFCCRAIHIEMLDDMSTDAFINGLRCFIAIRGAVHQIRCDQGSNFIGARNELTKAMEEIDTNRLVTFLAEKQCDFVFNAPHSSHTGGVWERQIRTVRSVLRSTLSQSSGRLDDSSLRTFFYEAMSIVNSRPLTVDSLTDPSSPEPLTPNHLLTLKPTQALPPPGKFVREDVYARKRWRHVQYLAEQFWGRWHKEYVSNITTRQCWHTPRRNMQVGDIVLEKAVDLPRNEWRLARIIEAVTDKDGLVRRVKIQFGDRNLGKDGKRPHKPSVVERPVQKLVLLMEAA", "length": 1973, "header": "tr|A0A8M9PPU1-1|A0A8M9PPU1_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC101885430 PE=4 SV=1 CANONICAL=A0A8M9PPU1-1" }, "locus": {} }, { "isoform_ac": "A0AC58HM25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1/entry#A0AC58HM25-1", "sequence": { "sequence": "MPHVKGLEILNDCEENRKLVSKLPDWAAARWNRQTTQTLSETQDFPTFQEFAHFMSVEAEVACNPVTSFHALHVSEPNKEKIYFKGSKPKANVFHTKTVTQHDNSKPTGKVNKPCLFCQNGEHQIHECSKFSARSLEERRQFVKDTRLCYGCLRLGHSAKDCRSRHCCNTCKGRHPTCLHDDSFNRKVRSSAQSPENVHEGVATMSLSVESGCTPVNTSMIVPVWLSTHKDPVSEKLVYALLDTQSDSVFIECAVCKSLKVDSCPVTLKLTTLVGKDSLMSSERISGLRVRGFNSSLIIDLPPAYTKECIPVDRAHIPTMETASHWKHLATLADKIPPLQNCEVGLLIGYNCSRALAPREVILGTENEPYAVRTDLGWSIIGPSLTHFEPQSSAAMCHRVSIKEIPAVTPTDVIKVLESDFKDTEGPTKVKSQEDIMFLRKLEKNIRLNKDSHLEMPLPFRKRPYLPDNKPLAVIRLQHLKRRLMRDQEYREHYVTFMEEVIEKGNAEQVFEEGREGERWYIPHHGVYHSKKPGKLRIVFDCSARYKGTSLNDHLLTGPDLMNSLTGILLRFRQYPVALMCDVEKMFHQFHVDHADRDYLRFLWWRNGDFNSQPQTFRMTVHLFGASSSPGCANYGLKHLAREGERLYPLGSQFIMQDFYMDDGVSSIESTEKAIKLAEEARQLCALGSLRLHKFVSNDKEVLKTIPPSECAVDVTAVDLALTDQPLERALGIYWSLEQDNFKFRITVKDQPATRRGILSIVASLFDPLGFLAPFVLKGKTILQEMCRSGMGWDDNLPADLQSAWEHWKADLVNLEKIEVPRCIVPSGFGRIIRREIHHFSDASMSGYGQCSYLRLENEQGDISCSLLMAKSRVAPLKITTIPRLELAAAVVSVAVNDMLKEEMNLADAETFFWTDSQVVLGYINNEARRFHTFVANRVQRIHRTTTPQQWRYICSDENPADYASRGLSVNNLVTSNWFRGPKVLWERQIPPPMEISKQLPIGDPEVKKVQSLNTQTVQYSCLSDRLTKLSSWSKAIQAVARLIRRVRKDKSHNHSTLAERNDAQCIIIKDLQKQTYAEEITLLRKGKQLPRSNRLYNLDTFVDQDGLLKVGGRLCEASIPNAVKYPVILPKEHQLTKLLIADCHEKMAHQGKGMTINEIRSRGFWITEVNRTVASFVRQCVRCRKLRGPTEEQKMANLPSERIEPSPPFTYSGMDVFGPFITCKGRKSNKRYGLLFTCFCCRAIHIEMLDDMSTDAFINGLRCFIAIRGAVHQIRCDQGSNFIGARNELTKAMEEIDTNRLVTFLAEKQCDFVFNAPHSSHTGGVWERQIRTVRSVLRSTLSQSSGRLDDSSLRTFFYEAMSIVNSRPLTVDSLTDPSSPEPLTPNHLLTLKPTQALPPPGKFVREDVYARKRWRHVQYLAEQFWGRWHKEYVSNITTRQCWHTPRRNMQVGDIVLEKAVDLPRNEWRLARIIEAVTDKDGLVRRVKIQFGDRNLGKDGKRPHKPSVVERPVQKLVLLMEAA", "length": 1523, "header": "tr|A0AC58HM25-1|A0AC58HM25_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC101885430 PE=4 SV=1 CANONICAL=A0A8M9PPU1-1" }, "locus": {} }, { "isoform_ac": "A0AC58HM47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1/entry#A0AC58HM47-1", "sequence": { "sequence": "MSLSVESGCTPVNTSMIVPVWLSTHKDPVSEKLVYALLDTQSDSVFIECAVCKSLKVDSCPVTLKLTTLVGKDSLMSSERISGLRVRGFNSSLIIDLPPAYTKECIPVDRAHIPTMETASHWKHLATLADKIPPLQNCEVGLLIGYNCSRALAPREVILGTENEPYAVRTDLGWSIIGPSLTHFEPQSSAAMCHRVSIKEIPAVTPTDVIKVLESDFKDTEGPTKVKSQEDIMFLRKLEKNIRLNKDSHLEMPLPFRKRPYLPDNKPLAVIRLQHLKRRLMRDQEYREHYVTFMEEVIEKGNAEQVFEEGREGERWYIPHHGVYHSKKPGKLRIVFDCSARYKGTSLNDHLLTGPDLMNSLTGILLRFRQYPVALMCDVEKMFHQFHVDHADRDYLRFLWWRNGDFNSQPQTFRMTVHLFGASSSPGCANYGLKHLAREGERLYPLGSQFIMQDFYMDDGVSSIESTEKAIKLAEEARQLCALGSLRLHKFVSNDKEVLKTIPPSECAVDVTAVDLALTDQPLERALGIYWSLEQDNFKFRITVKDQPATRRGILSIVASLFDPLGFLAPFVLKGKTILQEMCRSGMGWDDNLPADLQSAWEHWKADLVNLEKIEVPRCIVPSGFGRIIRREIHHFSDASMSGYGQCSYLRLENEQGDISCSLLMAKSRVAPLKITTIPRLELAAAVVSVAVNDMLKEEMNLADAETFFWTDSQVVLGYINNEARRFHTFVANRVQRIHRTTTPQQWRYICSDENPADYASRGLSVNNLVTSNWFRGPKVLWERQIPPPMEISKQLPIGDPEVKKVQSLNTQTVQYSCLSDRLTKLSSWSKAIQAVARLIRRVRKDKSHNHSTLAERNDAQCIIIKDLQKQTYAEEITLLRKGKQLPRSNRLYNLDTFVDQDGLLKVGGRLCEASIPNAVKYPVILPKEHQLTKLLIADCHEKMAHQGKGMTINEIRSRGFWITEVNRTVASFVRQCVRCRKLRGPTEEQKMANLPSERIEPSPPFTYSGMDVFGPFITCKGRKSNKRYGLLFTCFCCRAIHIEMLDDMSTDAFINGLRCFIAIRGAVHQIRCDQGSNFIGARNELTKAMEEIDTNRLVTFLAEKQCDFVFNAPHSSHTGGVWERQIRTVRSVLRSTLSQSSGRLDDSSLRTFFYEAMSIVNSRPLTVDSLTDPSSPEPLTPNHLLTLKPTQALPPPGKFVREDVYARKRWRHVQYLAEQFWGRWHKEYVSNITTRQCWHTPRRNMQVGDIVLEKAVDLPRNEWRLARIIEAVTDKDGLVRRVKIQFGDRNLGKDGKRPHKPSVVERPVQKLVLLMEAA", "length": 1319, "header": "tr|A0AC58HM47-1|A0AC58HM47_DANRE Computationally mapped isoform of Uncharacterized protein isoform X3 OS=Danio rerio OX=7955 GN=LOC101885430 PE=4 SV=1 CANONICAL=A0A8M9PPU1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 123, "start_aa": "Thr", "end_pos": 123, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr123", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 859, "start_aa": "Thr", "end_pos": 859, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr859", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101885430", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885430", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA integration", "id": "GO:0015074", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015074", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPU1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1504, "end_pos": 1506, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1621, "end_pos": 1623, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1886, "end_pos": 1888, "annotation": "n_glycosylation_sequon" }, { "start_pos": 308, "end_pos": 310, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 667, "end_pos": 669, "annotation": "n_glycosylation_sequon" }, { "start_pos": 744, "end_pos": 746, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PPU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1" }, { "id": "PS50158", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50158" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CCHC-type", "eco_id": "ECO_0000259", "start_pos": 599, "end_pos": 614, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PPU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPU1" }, { "id": "PS50994", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50994" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrase catalytic", "eco_id": "ECO_0000259", "start_pos": 1655, "end_pos": 1844, "start_aa": "Glu", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 123, 859 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 1504, "end_pos": 1506 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 1621, "end_pos": 1623 }, { "start_pos": 1886, "end_pos": 1888 }, { "start_pos": 308, "end_pos": 310 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 667, "end_pos": 669 }, { "start_pos": 744, "end_pos": 746 }, { "start_pos": 801, "end_pos": 803 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PPV1-1", "uniprot_ac": "A0A8M9PPV1", "uniprot_id": "A0A8M9PPV1_DANRE", "mass": { "chemical_mass": 41666.0, "monoisotopic_mass": 41666.0 }, "refseq": { "ac": "XP_021329058", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329058" }, "gene_names": [ { "name": "LOC110439056", "type": "recommended", "evidence": [ { "id": "A0A8M9PPV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPV1" } ] }, { "name": "LOC110439056", "type": "synonym", "evidence": [ { "id": "XP_021329058", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329058" } ] } ], "protein_names": [ { "name": "YqaJ viral recombinase domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8M9PPV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPV1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021329058", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329058" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021329058.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329058", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329058" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPV1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPV1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110439056", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPV1", "locus": {} } ], "crossref": [ { "id": "A0A8M9PPV1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PPV1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd22343", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22343", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110439056", "url": "https://www.ncbi.nlm.nih.gov/gene/110439056", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011335", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011335", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051703", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051703", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110439056", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110439056", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR46609", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46609", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46609:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46609:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09588", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09588", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021329058", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329058", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PPV1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PPV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPV1-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGVKTVPTALSCTSALQTWHRPRTKGIRPEPMDEVVVRKPKAAGRSCVKSTLYQAYPGPFPDPALLSVGDKLRDLRPQLGICSILCGLSSMELVESKFGQVPKGSVLSYQCPTAVSHEICKHPEAPSFPKLPLHGYRLDRHMNYVPSFEEYYHIESLMVTSELSCIIEKNTREQSENPLWKELRQPRLTSSRFGEVYSARGDSSSEALAVRMLRGVRQTSAMKRGIELEPEVLQLYSDFCGVNVSPSGFVIHPDAPYLGTSPDAKVYDPSEKPPFGLAEVKCPNVNSIAEATHIKFTNGQAKLKRNHKYFWQVLGQLAITGLPWCDFITSTKSDLTVERIWKDESLINDLKKKLDLFYFNTYMQTYLKNQ", "length": 370, "header": "tr|A0A8M9PPV1-1|A0A8M9PPV1_DANRE Isoform 1 of YqaJ viral recombinase domain-containing protein OS=Danio rerio OX=7955 GN=LOC110439056 PE=4 SV=2 CANONICAL=A0A8M9PPV1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PPV1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPV1/entry#A0A8M9PPV1-1", "sequence": { "sequence": "MGVKTVPTALSCTSALQTWHRPRTKGIRPEPMDEVVVRKPKAAGRSCVKSTLYQAYPGPFPDPALLSVGDKLRDLRPQLGICSILCGLSSMELVESKFGQVPKGSVLSYQCPTAVSHEICKHPEAPSFPKLPLHGYRLDRHMNYVPSFEEYYHIESLMVTSELSCIIEKNTREQSENPLWKELRQPRLTSSRFGEVYSARGDSSSEALAVRMLRGVRQTSAMKRGIELEPEVLQLYSDFCGVNVSPSGFVIHPDAPYLGTSPDAKVYDPSEKPPFGLAEVKCPNVNSIAEATHIKFTNGQAKLKRNHKYFWQVLGQLAITGLPWCDFITSTKSDLTVERIWKDESLINDLKKKLDLFYFNTYMQTYLKNQ", "length": 370, "header": "tr|A0A8M9PPV1-1|A0A8M9PPV1_DANRE Isoform 1 of YqaJ viral recombinase domain-containing protein OS=Danio rerio OX=7955 GN=LOC110439056 PE=4 SV=2 CANONICAL=A0A8M9PPV1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110439056", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110439056", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA repair", "id": "GO:0006281", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006281", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PPV1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPV1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PPV1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PPV1" }, { "id": "PF09588", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09588" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "YqaJ viral recombinase", "eco_id": "ECO_0000259", "start_pos": 180, "end_pos": 322, "start_aa": "Trp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 243, "end_pos": 245 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PQ00-1", "uniprot_ac": "A0A8M9PQ00", "uniprot_id": "A0A8M9PQ00_DANRE", "mass": { "chemical_mass": 84470.0, "monoisotopic_mass": 84470.0 }, "refseq": { "ac": "XP_021324331", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324331" }, "gene_names": [ { "name": "LOC108179167", "type": "recommended", "evidence": [ { "id": "A0A8M9PQ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ00" } ] }, { "name": "LOC108179167", "type": "synonym", "evidence": [ { "id": "XP_021324331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324331" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PQ00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ00/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021324331", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324331" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021324331.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324331", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324331" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQ00", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ00" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108179167", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ00", "locus": {} } ], "crossref": [ { "id": "A0A8M9PQ00", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PQ00", "database": "AlphaFoldDB", "categories": [] }, { "id": "108179167", "url": "https://www.ncbi.nlm.nih.gov/gene/108179167", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:108179167", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179167", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_021324331", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324331", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PQ00", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQ00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I5Z7", "url": "https://www.uniprot.org/uniprotkb/A0AC58I5Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I5Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I5Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MEVEISCEITKRQKKAQQGKERPGNGTNNEKDKVEKQKKKKKKSRVGSFIRAALKWFCFSPRNESFQLSSSDDYENEVYQKMMVKVEEEKEMIQKEEVVEVVEKVEKVTKEEDKILEKEEEVVIELEEGKEKEKDNTNEEKPEEEGKRKRKKKNISSRLSEEEFWRRRKIEEERVEEKEEEVVIEQKEMEKENINEEKPKDEKNMEEEKVKKKRRRRRRPRNCSVEEEAVKENKSEEVEKNEEKEMNNIEIEENMEEEKVKKKRRRRRRPRNCSVEEEVAKEKESEEVEKNAEEKEMKDIEIEENMEEEKVKKKRRRRRRPRNCSVEEVAAKENESEEVEKNAEEKEMKDIEIEENMEEEKVEKNEEKEMNDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEVAKEKESQEVEKNAEEKEMNDIEIEENMEEEKVKKKRRRRRPRNCSVEEEAVKENESEEVEKNAEEKEMKDFEIEENMEEEKVKKKRRRRRPRNCSVEEEAVKENESEEVEKNAEEKEEMKDIEIEENMEEEKVKKKRRRRRKPRNCSVEEEAAKENESEEVEKNAEEKEMKDFEIEENMEEEKVKKKRRRRRRPRNCSVEEEAAKENESEEMEKNAEEKEMKDIEIEENMEEMKEKKKRRRRRRPRNCSVEEEAVKENESEEMEKNGRRWPKLHLEKERQSYVHVQ", "length": 689, "header": "tr|A0A8M9PQ00-1|A0A8M9PQ00_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC108179167 PE=4 SV=3 CANONICAL=A0A8M9PQ00-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PQ00-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ00/entry#A0A8M9PQ00-1", "sequence": { "sequence": "MEVEISCEITKRQKKAQQGKERPGNGTNNEKDKVEKQKKKKKKSRVGSFIRAALKWFCFSPRNESFQLSSSDDYENEVYQKMMVKVEEEKEMIQKEEVVEVVEKVEKVTKEEDKILEKEEEVVIELEEGKEKEKDNTNEEKPEEEGKRKRKKKNISSRLSEEEFWRRRKIEEERVEEKEEEVVIEQKEMEKENINEEKPKDEKNMEEEKVKKKRRRRRRPRNCSVEEEAVKENKSEEVEKNEEKEMNNIEIEENMEEEKVKKKRRRRRRPRNCSVEEEVAKEKESEEVEKNAEEKEMKDIEIEENMEEEKVKKKRRRRRRPRNCSVEEVAAKENESEEVEKNAEEKEMKDIEIEENMEEEKVEKNEEKEMNDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEVAKEKESQEVEKNAEEKEMNDIEIEENMEEEKVKKKRRRRRPRNCSVEEEAVKENESEEVEKNAEEKEMKDFEIEENMEEEKVKKKRRRRRPRNCSVEEEAVKENESEEVEKNAEEKEEMKDIEIEENMEEEKVKKKRRRRRKPRNCSVEEEAAKENESEEVEKNAEEKEMKDFEIEENMEEEKVKKKRRRRRRPRNCSVEEEAAKENESEEMEKNAEEKEMKDIEIEENMEEMKEKKKRRRRRRPRNCSVEEEAVKENESEEMEKNGRRWPKLHLEKERQSYVHVQ", "length": 689, "header": "tr|A0A8M9PQ00-1|A0A8M9PQ00_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC108179167 PE=4 SV=3 CANONICAL=A0A8M9PQ00-1" }, "locus": {} }, { "isoform_ac": "A0AC58I5Z7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ00/entry#A0AC58I5Z7-1", "sequence": { "sequence": "MEVEISCQITKRQKKAQQGKERPGNGTNNEKDKVEKQKKKKKKSRVGSFIRAALKWFCFSPRNESFQLSSSDDYENEVYQKMMVKVEEEKEMIQKEEVVEKVEVVEKVEKVTKEEDEILEKEEEVVIELEEGKEKEKDDTNEEKPEEEGKRKRKKKNINSRLSEEEFWRRKIEEERVEEKEEEVVIEQKKMEKESINEEKPKDEENMEEEKVKKKRRRRRRPRNCSVEEEAVKENKSEEVEKNEEKEMNDIEIEENMEEEKVKKKRRRRRRPRNCSVEEEVAKEKESQEVEKNAEEKEMNDIEIEENMEEEKVKKKRRRRRPRNCSVEEEAVKENESEEVEKNAEEKEMKDFEIEENMEEEKVKKKRRRRRPRNCSVEEEAVKENESEEVEKNAEEKEEMKDIEIEENMEEEKVKKKRRRRRKPRNCSVEEEAAKENESEEVEKNAEEKEMKDFEIEENMEEEKVKKKRRRRRRPRNCSVEEEAAKENESEEMEKNAEEKEMKDIEIEENMEEMKEKKKRRRRRRPRNCSVEEEAVKENESEEMEKNGRRWPKLHLEKERQSYVHVQ", "length": 567, "header": "tr|A0AC58I5Z7-1|A0AC58I5Z7_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC108179167 PE=4 SV=1 CANONICAL=A0A8M9PQ00-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108179167", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179167", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 233, "end_pos": 235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 272, "end_pos": 274, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 457, "end_pos": 459, "annotation": "n_glycosylation_sequon" }, { "start_pos": 496, "end_pos": 498, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" }, { "start_pos": 559, "end_pos": 561, "annotation": "n_glycosylation_sequon" }, { "start_pos": 599, "end_pos": 601, "annotation": "n_glycosylation_sequon" }, { "start_pos": 610, "end_pos": 612, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 661, "end_pos": 663, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 233, "end_pos": 235 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 272, "end_pos": 274 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 334, "end_pos": 336 }, { "start_pos": 396, "end_pos": 398 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 457, "end_pos": 459 }, { "start_pos": 496, "end_pos": 498 }, { "start_pos": 507, "end_pos": 509 }, { "start_pos": 548, "end_pos": 550 }, { "start_pos": 559, "end_pos": 561 }, { "start_pos": 599, "end_pos": 601 }, { "start_pos": 610, "end_pos": 612 }, { "start_pos": 63, "end_pos": 65 }, { "start_pos": 650, "end_pos": 652 }, { "start_pos": 661, "end_pos": 663 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PQ11-1", "uniprot_ac": "A0A8M9PQ11", "uniprot_id": "A0A8M9PQ11_DANRE", "mass": { "chemical_mass": 112126.0, "monoisotopic_mass": 112126.0 }, "refseq": { "ac": "XP_697440", "name": "ankyrin repeat and MYND domain-containing protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697440" }, "gene_names": [ { "name": "ankmy1", "type": "recommended", "evidence": [ { "id": "A0A8M9PQ11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ11" } ] }, { "name": "ankmy1", "type": "synonym", "evidence": [ { "id": "XP_697440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697440" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and MYND domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PQ11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ11/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and MYND domain-containing protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_697440", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697440" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_697440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697440" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQ11", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ11" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ankmy1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ11", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050208-740", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-740", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "568987", "url": "https://www.ncbi.nlm.nih.gov/gene/568987", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003409", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003409", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PQ11", "url": "https://www.orthodb.org/?gene=A0A8M9PQ11", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15897", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15897", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15897:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15897:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_697440", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697440", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PQ11", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ11", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQ11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ11-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IH41", "url": "https://www.uniprot.org/uniprotkb/A0AC58IH41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IH41-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IH41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050208-740", "url": "https://zfin.org/ZDB-GENE-050208-740", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MWDISCKRNGHGIQEWPDGCKYEGEFINNLKHGDGVFTWTNGESYKGSFFKDYRHGKGTYSWPDGSKYTGKFYLNRKEGYGVQVFSDGSTFQGLYHAGERFGPGVMTYPDGRQDLGLWHREKLLQMCSTMEDGFSLEHFPEYMTRRLEKDLKQPLFPVDVESRADRGHYVSDLCLLEDEDHFILPPEIERYSTDSDHLPIPRRLRRELDLHFFGTSEISTESLSIAVPLQQRLNAHIQRHRFEAETLDWDVAAVLNLNRAQFGPKGPLELNSERLIMEASRGECRNVYRILRDGEIHPNVSDAKGHTALIAATVYCHDDVINMLLDNGADVNKLNAEGMSALAVCMLLYYPLQSLHETLAEKVPRNISPEPQIKPLEDVAHESSPDPVTETARDEREPVTSETNQTNPRLEPENLEAHGKINDNETVVQLDELNTSEEIDKNTDLIRKETLLELENEQNIRSQSVQVLDDLVPVGCVSWKEAIKEEDLESSVRSDDPDFNSACSMLSFQIEVTEEILQKSAEILSLTQTLSPTDTQETVRRIALLKTEHRKRWATVELLLERGADPNSSTVPVPVIFLAIKAAHVNSVRRLLECGARTDIPLPPEQKGLYPLHIAAGLLGAEGPEITELLLHALADPNHKALDQNEVFQLDQVFEDPHVCQFSDAHVQFSQEGGRTALHVACQRDSEYTNARDVVALLLSHCASPNEVWSGHSPLSLAIASGNHLAVDELLSAGADVNLPLTRHIGSALCALTNINYDHEQQPRNHVKLLDKLVKAGADVLMPVMVCDGRRCTMGTVVDYAHITFQQNRRMSRTPYHALSKHERHVYNARRQLLGLMGDLMRQTASRGQEEQGQDEFGVSPSERSVYSRSAVTSSLLNSPESISRMSCNKQRAHRKWRFCEECGRSVGVHLTACSRCHEVYYCSNTCRGRSWEQRHREKCVRLPVVNGKSNSGRIEPNRPRSSSSPKDAKANPIHPSISPEIQEYDPNENYSFI", "length": 994, "header": "tr|A0A8M9PQ11-1|A0A8M9PQ11_DANRE Isoform 1 of Ankyrin repeat and MYND domain-containing protein 1 isoform X1 OS=Danio rerio OX=7955 GN=ankmy1 PE=4 SV=1 CANONICAL=A0A8M9PQ11-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PQ11-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ11/entry#A0A8M9PQ11-1", "sequence": { "sequence": "MWDISCKRNGHGIQEWPDGCKYEGEFINNLKHGDGVFTWTNGESYKGSFFKDYRHGKGTYSWPDGSKYTGKFYLNRKEGYGVQVFSDGSTFQGLYHAGERFGPGVMTYPDGRQDLGLWHREKLLQMCSTMEDGFSLEHFPEYMTRRLEKDLKQPLFPVDVESRADRGHYVSDLCLLEDEDHFILPPEIERYSTDSDHLPIPRRLRRELDLHFFGTSEISTESLSIAVPLQQRLNAHIQRHRFEAETLDWDVAAVLNLNRAQFGPKGPLELNSERLIMEASRGECRNVYRILRDGEIHPNVSDAKGHTALIAATVYCHDDVINMLLDNGADVNKLNAEGMSALAVCMLLYYPLQSLHETLAEKVPRNISPEPQIKPLEDVAHESSPDPVTETARDEREPVTSETNQTNPRLEPENLEAHGKINDNETVVQLDELNTSEEIDKNTDLIRKETLLELENEQNIRSQSVQVLDDLVPVGCVSWKEAIKEEDLESSVRSDDPDFNSACSMLSFQIEVTEEILQKSAEILSLTQTLSPTDTQETVRRIALLKTEHRKRWATVELLLERGADPNSSTVPVPVIFLAIKAAHVNSVRRLLECGARTDIPLPPEQKGLYPLHIAAGLLGAEGPEITELLLHALADPNHKALDQNEVFQLDQVFEDPHVCQFSDAHVQFSQEGGRTALHVACQRDSEYTNARDVVALLLSHCASPNEVWSGHSPLSLAIASGNHLAVDELLSAGADVNLPLTRHIGSALCALTNINYDHEQQPRNHVKLLDKLVKAGADVLMPVMVCDGRRCTMGTVVDYAHITFQQNRRMSRTPYHALSKHERHVYNARRQLLGLMGDLMRQTASRGQEEQGQDEFGVSPSERSVYSRSAVTSSLLNSPESISRMSCNKQRAHRKWRFCEECGRSVGVHLTACSRCHEVYYCSNTCRGRSWEQRHREKCVRLPVVNGKSNSGRIEPNRPRSSSSPKDAKANPIHPSISPEIQEYDPNENYSFI", "length": 994, "header": "tr|A0A8M9PQ11-1|A0A8M9PQ11_DANRE Isoform 1 of Ankyrin repeat and MYND domain-containing protein 1 isoform X1 OS=Danio rerio OX=7955 GN=ankmy1 PE=4 SV=1 CANONICAL=A0A8M9PQ11-1" }, "locus": {} }, { "isoform_ac": "A0AC58IH41-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ11/entry#A0AC58IH41-1", "sequence": { "sequence": "MQECLPNPQRWRNSSECERCKRTYSSHSSNVVKDHHVETSSFIYSATTTTPKTTCLMRYVNELCRLALQVYCHDDVINMLLDNGADVNKLNAEGMSALAVCMLLYYPLQSLHETLAEKVPRNISPEPQIKPLEDVAHESSPDPVTETARDEREPVTSETNQTNPRLEPENLEAHGKINDNETVVQLDELNTSEEIDKNTDLIRKETLLELENEQNIRSQSVQVLDDLVPVGCVSWKEAIKEEDLESSVRSDDPDFNSACSMLSFQIEVTEEILQKSAEILSLTQTLSPTDTQETVRRIALLKTEHRKRWATVELLLERGADPNSSTVPVPVIFLAIKAAHVNSVRRLLECGARTDIPLPPEQKGLYPLHIAAGLLGAEGPEITELLLHALADPNHKALDQNEVFQLDQVFEDPHVCQFSDAHVQFSQEGGRTALHVACQRDSEYTNARDVVALLLSHCASPNEVWSGHSPLSLAIASGNHLAVDELLSAGADVNLPLTRHIGSALCALTNINYDHEQQPRNHVKLLDKLVKAGADVLMPVMVCDGRRCTMGTVVDYAHITFQQNRRMSRTPYHALSKHERHVYNARRQLLGLMGDLMRQTASRGQEEQGQDEFGVSPSERSVYSRSAVTSSLLNSPESISRMSCNKQRAHRKWRFCEECGRSVGVHLTACSRCHEVYYCSNTCRGRSWEQRHREKCVRLPVVNGKSNSGRIEPNRPRSSSSPKDAKANPIHPSISPEIQEYDPNENYSFI", "length": 750, "header": "tr|A0AC58IH41-1|A0AC58IH41_DANRE Computationally mapped isoform of Ankyrin repeat and MYND domain-containing protein 1 isoform X2 OS=Danio rerio OX=7955 GN=ankmy1 PE=4 SV=1 CANONICAL=A0A8M9PQ11-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZQ67-1", "protein_name": "Ankyrin repeat and MYND domain containing 1", "gene_name": "Ankmy1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGGRCRPRTVGEGLGRRWRWWWRWRWWWRRRWRRGAGTTGSRAGSRPARPRAVRRPAQAGLGSHRGRCVRPRACAPRRRDRRSRTRGRTPWKAVRLQAARWQLGLAGLSWRRDRRFPRDAGLKRREMEEVRSIVTLDSQGSKTFSSRGLEGQSGRSPDTESQHSSKSYTFFSRRDHPGDLREDEESEGTTGEEELKGTYMHLVQGVQEWQDGCVYKGEFGLNMKLGHGEFSWPTGEIYRGQFYRDHYHGMGTYSWPDGSSFTGTFYLSQREGYGTMYTKAKLFQGLYKEDQRFGPGIETYPDGSQDVGIWFREYLLKLCTRVPSSFSLINYPEFSAFLTNTRKRISLSDEEKVEVSLSEEQDPFYYDYKQYLLNDDLKLPPEIHVYSTNNSHLPMTNALRKELDNQIFMNEIPPFIEDEEPWLITNETPLLVKIQKQTYKFRNKDAHANWNIAAILEGNRSKFGPSGPKEQISKKMIMKAEEGDYNWIFGILRDNLACADVADSKGYTVLAAAAIHSHINIVNLLLDYGADVNKRSDEGITPLSMCFLQYYPSKSFHPNIAERTLLQESPKPLVTPKISFLFADPNTDSSYDVGAHILGGEELKTSLLPSSSPEESLASMPPPESNNVLQKRDVSPVKTVSTEVEKETEDVAENVDASTLYSADTNFESTICLRNYSINVSRDILEKSAQAYSSLVQHSCFPYKGTVRKLAQTMAERRNRWMTIMLLLRRGADPNLCQVPMQALFLAVKAGDVEGVRLLLMNGAQTDIQYPPQLQSLTPLHIAASLPGEEGVKITELLLHAVTNVDAKAADQDYPYKGGKGDLPSSLKLNNEPGPPKSYYSPYTRIPEEGGRTALHVACEREDNKKCARDIVRLLLSHRANPNTLWSGHSPLSLSIASGNDLVVKELLAQGADPNLPLTKGLGTALCVVCDLFYEQQRSTDNKIALIDRLISYGADVLKPVTIVQGERTAVGTAVDYGYFKFYQDRKIAHCPFHALMPAEREIFIARKRLLEYLGLQLRLAVLNKESRLDVKALYLSKRAELAPCHRMKKRSSSPAKSPSMEKQTLPFYKFCYQCGRSIGVRLSPCPRCYGILTCSKYCKTKAWIEFHKKDCNDIMAMKKDLLAQRSQEPKSENNLWHINQASQTVQLRKEEDQENQASKNAQFEKEDKDNQESKSVQFKKEDQDNQASKSIQFKESTEQKNQVSKSLQLKKNKEQDNQVSKSVQLKRDPEQKEVSLTRSCWTA", "length": 1245 }, "evidence": [ { "id": "RGD:1595229", "url": "https://alliancegenome.org/gene/RGD:1595229#orthology", "database": "AGR" }, { "id": "MGI:3045261", "url": "https://alliancegenome.org/gene/MGI:3045261#orthology", "database": "AGR" }, { "id": "HGNC:20987", "url": "https://alliancegenome.org/gene/HGNC:20987#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-740", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-740#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C0W1-1", "protein_name": "Ankyrin repeat and MYND domain-containing protein 1", "gene_name": "Ankmy1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLGYGEFSWPTGEAYHGQFYRDHFHGLGTYTWPDGSSFTGTFYLSQREGYGTMHTKTMLFQGLYKEDQRFGPGIETYPDGSQDVGLWFREYLLKLCTRVPSGFSLVNYPEFLAFLTKSRRRLDLSDEKVELGLSEEQDPFFYDYKQYLLNDELKLPPEMHVYSTDNSHLPMTDSLRQELDDHIFMNEIPPFIEDEEPWLITNETPLLVKIQKQTYKFRNKDAHTSWNIPAILEGNRSRFGPSGPKEQISKKMIMKAEEGDYNWIFGILRDNLACADVADSKGYTVLAAAAMHSHLDIVNLLLDFGADVNKRSDEGITPLSMCFLQYYPCKSFHPNIAERTLLQESPKSLVTPKISFLLADANIDYLYDVGMPIAGGDELKTSSLDDSLASMQTPESSNMLHKEEVSPVKTVSTDVEKESEGAAENVDASTLYSVDTNFESTKCLRNYTINVSRDIMEKSAQAYSSLPQHPCFPYKGTVRKMAQSMVERRNRWMTITLLLRRGADPNLCQVPMQALFLAVKAGDVEGVRLLLMSGAQTDIQFPPQLQSLTPLHIAVSLPGEEGVKITELLLHVITNVDAKAADEDYVYKGGKADLLPSSLKLNNEPGPPKSFYSTHTFIPEEGGRTALHVACEREDNKKCARDIVRLLLSHRANPNVLWSGHSPLSLAIASGNDLVVKELLSQGADPNLPLTKGLGTALCVVCDLVYEQQRSVENKIALIDRLISYGADVLNPVTLVQGDRTAVGTAVDYGYFKFFQDRKIAHCPFHALMPAEREVFMARKRLLEYLGLQLRLAVLSKESRLDTKALYLSKRAELAPCHRLKKKGSSSVRTQSSEKQSIPFYKFCYQCGRSIGVRLSPCPRCYGILTCSKYCKTKAWIEFHKKDCNDIMAMIPHLEGSAWRVAESP", "length": 906 }, "evidence": [ { "id": "RGD:1595229", "url": "https://alliancegenome.org/gene/RGD:1595229#orthology", "database": "AGR" }, { "id": "MGI:3045261", "url": "https://alliancegenome.org/gene/MGI:3045261#orthology", "database": "AGR" }, { "id": "HGNC:20987", "url": "https://alliancegenome.org/gene/HGNC:20987#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-740", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-740#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2S6-1", "protein_name": "Ankyrin repeat and MYND domain-containing protein 1", "gene_name": "ANKMY1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYQGEFGLNMKLGYGKFSWPTGESYHGQFYRDHCHGLGTYMWPDGSSFTGTFYLSHREGYGTMYMKTRLFQGLYKADQRFGPGVETYPDGSQDVGLWFREQLIKLCTQIPSGFSLLRYPEFSSFITHSPARISLSEEEKTEWGLQEGQDPFFYDYKRFLLNDNLTLPPEMYVYSTNSDHLPMTSSFRKELDARIFLNEIPPFVEDGEPWFIINETPLLVKIQKQTYKFRNKPAHTSWNMGAILEGKRSGFAPCGPKEQLSMEMILKAEEGNHEWICRILKDNFASADVADAKGYTVLAAAATHCHNDIVNLLLDCGADVNKCSDEGLTALSMCFLLHYPAQSFKPNVAERTIPEPQEPPKFPVVPILSSSFMDTNLESLYYEVNVPSQGSYELRPPPAPLLLPRVSGSHEGGHFQDTGQCGGSIDHRSSSLKGDSPLVKGSLGHVESGLEDVLGNTDRGSLCSAETKFESNVCVCDFSIELSQAMLERSAQSHSLLKMASPSPCTSSFDKGTMRRMALSMIERRKRWRTIKLLLRRGADPNLCCVPMQVLFLAVKAGDVDGVRLLLEHGARTDICFPPQLSTLTPLHIAAALPGEEGVQIVELLLHAITDVDAKASDEDDTYKPGKLDLLPSSLKLSNEPGPPQAYYSTDTALPEEGGRTALHMACEREDDNKCARDIVRLLLSHGANPNLLWSGHSPLSLSIASGNELVVKELLTQGADPNLPLTKGLGSALCVACDLTYEHQRNMDSKLALIDRLISHGADILKPVMLRQGEKEAVGTAVDYGYFRFFQDRRIARCPFHTLMPAERETFLARKRLLEYMGLQLRQAVFAKESQWDPTWLYLCKRAELIPSHRMKKKGPSLPRGLDVKEQGQIPFFKFCYQCGRSIGVRLLPCPRCYGILTCSKYCKTKAWTEFHKKDCGDLVAIVTQLEQVSRRREEFQ", "length": 941 }, "evidence": [ { "id": "RGD:1595229", "url": "https://alliancegenome.org/gene/RGD:1595229#orthology", "database": "AGR" }, { "id": "MGI:3045261", "url": "https://alliancegenome.org/gene/MGI:3045261#orthology", "database": "AGR" }, { "id": "HGNC:20987", "url": "https://alliancegenome.org/gene/HGNC:20987#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-740", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-740#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQ11", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ11" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 299, "end_pos": 301, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 404, "end_pos": 406, "annotation": "n_glycosylation_sequon" }, { "start_pos": 424, "end_pos": 426, "annotation": "n_glycosylation_sequon" }, { "start_pos": 434, "end_pos": 436, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" }, { "start_pos": 990, "end_pos": 992, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PQ11", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ11" }, { "id": "PS50865", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50865" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MYND-type", "eco_id": "ECO_0000259", "start_pos": 900, "end_pos": 940, "start_aa": "Cys", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 299, "end_pos": 301 }, { "start_pos": 366, "end_pos": 368 }, { "start_pos": 404, "end_pos": 406 }, { "start_pos": 424, "end_pos": 426 }, { "start_pos": 434, "end_pos": 436 }, { "start_pos": 567, "end_pos": 569 }, { "start_pos": 990, "end_pos": 992 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PQ42-1", "uniprot_ac": "A0A8M9PQ42", "uniprot_id": "A0A8M9PQ42_DANRE", "mass": { "chemical_mass": 28064.0, "monoisotopic_mass": 28064.0 }, "refseq": { "ac": "XP_021329148", "name": "cathepsin G-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329148" }, "gene_names": [ { "name": "LOC110439063", "type": "recommended", "evidence": [ { "id": "A0A8M9PQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ42" } ] }, { "name": "LOC110439063", "type": "synonym", "evidence": [ { "id": "XP_021329148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329148" } ] } ], "protein_names": [ { "name": "trypsin", "type": "recommended", "evidence": [ { "id": "A0A8M9PQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ42/entry#names_and_taxonomy" } ] }, { "name": "3.4.21.4", "type": "synonym", "evidence": [ { "id": "A0A8M9PQ42", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ42/entry#names_and_taxonomy" } ] }, { "name": "cathepsin G-like", "type": "synonym", "evidence": [ { "id": "XP_021329148", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329148" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021329148.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329148" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQ42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ42" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110439063", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ42", "locus": {} } ], "crossref": [ { "id": "A0A8M9PQ42", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PQ42", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110439063", "url": "https://www.ncbi.nlm.nih.gov/gene/110439063", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110439063", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110439063", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24271:SF87", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24271:SF87", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021329148", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329148", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PQ42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ42", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQ42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ42-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTIIIISLLLLVSLVPHLTFTAHVSIVDGQEAKPHSRPYMVSVQLFGQNICAGFLISDRFVLTAAQCWHHNRKALTVVVGAHDLRKCQHSKHFKVMCHITHPEFNSKTFENDIMLLKLKRKVPLNNKIRPISLPKNGERFKADTLCSVAGWGRLWTDGPVSDLLLEAKTAIVNDAECKLRWGYHYVPSMMICAFGHGGSCNGDGGGPLVCGNTAVGITIFRDRYLCNSRLLPNVYTKISAYVPWIRSIIGNV", "length": 252, "header": "tr|A0A8M9PQ42-1|A0A8M9PQ42_DANRE Isoform 1 of trypsin OS=Danio rerio OX=7955 GN=LOC110439063 PE=4 SV=2 CANONICAL=A0A8M9PQ42-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PQ42-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ42/entry#A0A8M9PQ42-1", "sequence": { "sequence": "MTIIIISLLLLVSLVPHLTFTAHVSIVDGQEAKPHSRPYMVSVQLFGQNICAGFLISDRFVLTAAQCWHHNRKALTVVVGAHDLRKCQHSKHFKVMCHITHPEFNSKTFENDIMLLKLKRKVPLNNKIRPISLPKNGERFKADTLCSVAGWGRLWTDGPVSDLLLEAKTAIVNDAECKLRWGYHYVPSMMICAFGHGGSCNGDGGGPLVCGNTAVGITIFRDRYLCNSRLLPNVYTKISAYVPWIRSIIGNV", "length": 252, "header": "tr|A0A8M9PQ42-1|A0A8M9PQ42_DANRE Isoform 1 of trypsin OS=Danio rerio OX=7955 GN=LOC110439063 PE=4 SV=2 CANONICAL=A0A8M9PQ42-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [ { "id": "dre:110439063", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110439063", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQ42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ42" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQ42", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ42" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": 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Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324391" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQ58", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ58" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108180292", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ58", "locus": {} } ], "crossref": [ { "id": "A0A8M9PQ58", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PQ58", "database": "AlphaFoldDB", "categories": [] }, { "id": "108180292", "url": "https://www.ncbi.nlm.nih.gov/gene/108180292", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052882", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052882", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108180292", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108180292", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR22467", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22467", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22467:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22467:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_021324391", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324391", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PQ58", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQ58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6Q5", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6Q5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I6Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I6Q5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVFDSQRTVMRFQSKIQRLQHDMDYNILERMITRDSPEFRSRGRAGGASEQRASSAAVVENQTAEMQRRGRRKTGVLSFFRKMGRAIHKLCCMDAAATSIVDHTDPSGSARAVASESRERTRKIYLKKDCSKVILRIVKGTPGSPDPCGVCVVSIDVDQPGISSVSVDPGPNGFYSDSFSPGPPGVLRLSLVLCPSGVFSVSLNARPSRGCRVSVDPGSSGFFSVSSYPGASRDFSVSGNPDASGGCRLSVDTGLFGGCAVSAASGPSDCGMSAAPGPSDCGMSAAPGPSDCSMAADPGPSDCSMAAAPGPSDCGMSADPGPSDCSMAADPGPSDCGMSAYPGPSGCTKPAAPEPSGCTIPADPGPSGCTTSAAPGPAPHWWISSSSPPSNRTNQMAVIQYSEGFITPADLTLYVLCVLVILLLHVVFVCI", "length": 431, "header": "tr|A0A8M9PQ58-1|A0A8M9PQ58_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC108180292 PE=4 SV=1 CANONICAL=A0A8M9PQ58-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PQ58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ58/entry#A0A8M9PQ58-1", "sequence": { "sequence": "MVFDSQRTVMRFQSKIQRLQHDMDYNILERMITRDSPEFRSRGRAGGASEQRASSAAVVENQTAEMQRRGRRKTGVLSFFRKMGRAIHKLCCMDAAATSIVDHTDPSGSARAVASESRERTRKIYLKKDCSKVILRIVKGTPGSPDPCGVCVVSIDVDQPGISSVSVDPGPNGFYSDSFSPGPPGVLRLSLVLCPSGVFSVSLNARPSRGCRVSVDPGSSGFFSVSSYPGASRDFSVSGNPDASGGCRLSVDTGLFGGCAVSAASGPSDCGMSAAPGPSDCGMSAAPGPSDCSMAADPGPSDCSMAAAPGPSDCGMSADPGPSDCSMAADPGPSDCGMSAYPGPSGCTKPAAPEPSGCTIPADPGPSGCTTSAAPGPAPHWWISSSSPPSNRTNQMAVIQYSEGFITPADLTLYVLCVLVILLLHVVFVCI", "length": 431, "header": "tr|A0A8M9PQ58-1|A0A8M9PQ58_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC108180292 PE=4 SV=1 CANONICAL=A0A8M9PQ58-1" }, "locus": {} }, { "isoform_ac": "A0AC58I6Q5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQ58/entry#A0AC58I6Q5-1", "sequence": { "sequence": "MVFDSQRTVMRFQSKIQRLQHDMDYNILERMITRDSPEFRSRGRAGGASEQRASSAAVVENQTAEMQRRGRRKTGVLSFFRKMGRAIHKLCCMDAAATSIVDHTDPSGSARAVASESRERTRKIYLKKDCSKVILRIVKGTPGSPDPCGVCVVSIDVDQPGISSVSVDPGPNGFYSDSFSPGPPGVLRLSLVLCPSGVFSVSLNARPSRGCRVSVDPGSSGFFSVSSYPGASRDFSVSGNPDASGGCRLSVDTGLFGGCAVSAASGPSDCGMSAAPGPSDCGMSAAPGPSDCSMAADPGPSDCSMAAAPGPSDCGMSADPGPSDCSMAADPGPSDCGMSAYPGPSGCTTSAAPGPAPHWWISSSSPPSNRTNQMAVIQYSEGFITPADLTLYVLCVLVILLLHVVFVCI", "length": 409, "header": "tr|A0AC58I6Q5-1|A0AC58I6Q5_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC108180292 PE=4 SV=1 CANONICAL=A0A8M9PQ58-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108180292", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108180292", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 391, "end_pos": 393 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PQI2-1", "uniprot_ac": "A0A8M9PQI2", "uniprot_id": "A0A8M9PQI2_DANRE", "mass": { "chemical_mass": 134467.0, "monoisotopic_mass": 134467.0 }, "refseq": { "ac": "XP_021333787", "name": "protein mono-ADP-ribosyltransferase PARP14 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333787" }, "gene_names": [ { "name": "si:ch211-163c2.3", "type": "recommended", "evidence": [ { "id": "A0A8M9PQI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI2" } ] }, { "name": "si:ch211-163c2.3", "type": "synonym", "evidence": [ { "id": "XP_021333787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333787" } ] } ], "protein_names": [ { "name": "Poly [ADP-ribose] polymerase", "type": "recommended", "evidence": [ { "id": "A0A8M9PQI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI2/entry#names_and_taxonomy" } ] }, { "name": "2.4.2.-", "type": "synonym", "evidence": [ { "id": "A0A8M9PQI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI2/entry#names_and_taxonomy" } ] }, { "name": "PARP", "type": "synonym", "evidence": [ { "id": "A0A8M9PQI2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI2/entry#names_and_taxonomy" } ] }, { "name": "protein mono-ADP-ribosyltransferase PARP14 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021333787", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333787" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021333787.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021333787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333787" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQI2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-163c2.3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI2", "locus": {} } ], "crossref": [ { "id": "A0A8M9PQI2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PQI2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01439", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01439", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100151073", "url": "https://www.ncbi.nlm.nih.gov/gene/100151073", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012317", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012317", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043472", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100151073", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100151073", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PQI2", "url": "https://www.orthodb.org/?gene=A0A8M9PQI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14453", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14453", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14453:SF107", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14453:SF107", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01661", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01661", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021333787", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333787", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PQI2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G305", "url": "https://www.uniprot.org/uniprotkb/A0AC58G305", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G305-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G305-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENYLYDVFFKASNLSDVALKHIKRYFEVRYRECVISNEGNDIYKISFANKNEQKNVLDQRDHFINIPGQRTVRVKASANQTCVAVVEQHNQVDRNLESSSSMQEQQQVQQTFPVSEKHFALIKEQFELYKNSDLPTLQIEQEPDVILLKGPKTEVLKCYQKLSTLKQGIIENRLSNYAFMNFLVSSDSINHLQKRFKQSLKSPVMIEISGSDLLLLSLSDGALKEAANAIETDLCSETIHLKKSSDFATLAFELSNAVKQANRESVKVELKYQNDSNSDTEVQLVGFTTKVTELMNILLEYKKKHRKHHVCLRLQYPEMAKHFSKILLMAGVKECSVEIKPTCSSSPCVHLTGPRCEVETLESYLQCVVTRHLEVKGPGVQQFFQGDGATTLRSVKSSCQVEILPTDVPENTISSSASSTNHSMDYDNILHIKVVVGLEQQQADVFVVPMVNTNMTSTLIGSSLLNKAGQQLQTNFNTAKGNRTLKSGEVLEVDAPQGLGCSKVLFLECAPQGINHNCENALRCGLGQIFALCERNLWGSVALPIIEPEDVLSIPVRDSVNILTQQISTFLSKSTHFLHTIRIPIMPNYSHSEEMFQIVLGTLHALMVDSTGQALFHSLTTDLDEVIMAVDRIKLHLVFGDITDEMTDAIVNTTDFNDFQTNGACKDILTKAGPSVQSLLKGASVAWRQIFTTPPGGLPCKIIMHVCGERSPSVIKTLAKEIVVQCEHGRYQSVAIPAICAGQGGLDPKVVAKSILEGVKEGVQGANLQYLKNIRIILLKINVFLAFKTVARQVFGASTQMTAPAPLHLSRSQAPSSPVCYDLSSLLASLPVTEDKAAFLVIGDRDKDVFDACTELQRAYDSQCLKESFYSDEMERLTKDELNQLRTKVHSLHLQLEINSSGKWVAKGLKDGVNEVARLMRDALRRQVREKEQDNLFTQVAWCILGPRSIWQKVPKKANHQLERADVNDGIVDAQGVKWTVDLRKLEATECDSGQVTALKRLENLSDFSFPIHWDSMNQKGLKVVALDPQSAEYKTVKADFQRTVLKTVLKIERIQNINLRRLYEARKSELEIKNDPAVGAGEKILYHGSAQASCSSIMSTNFNRNFAGQNGTVYGQGTYFAVNASYSANVNYAVPAADGTQQMFVARVLTGHYTMGFGDMRTAPVRVVPDQFYDSVVDYTQNPTMFVVFHDCQAYPDYLITFK", "length": 1205, "header": "tr|A0A8M9PQI2-1|A0A8M9PQI2_DANRE Isoform 1 of Poly [ADP-ribose] polymerase OS=Danio rerio OX=7955 GN=si:ch211-163c2.3 PE=3 SV=3 CANONICAL=A0A8M9PQI2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PQI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI2/entry#A0A8M9PQI2-1", "sequence": { "sequence": "MENYLYDVFFKASNLSDVALKHIKRYFEVRYRECVISNEGNDIYKISFANKNEQKNVLDQRDHFINIPGQRTVRVKASANQTCVAVVEQHNQVDRNLESSSSMQEQQQVQQTFPVSEKHFALIKEQFELYKNSDLPTLQIEQEPDVILLKGPKTEVLKCYQKLSTLKQGIIENRLSNYAFMNFLVSSDSINHLQKRFKQSLKSPVMIEISGSDLLLLSLSDGALKEAANAIETDLCSETIHLKKSSDFATLAFELSNAVKQANRESVKVELKYQNDSNSDTEVQLVGFTTKVTELMNILLEYKKKHRKHHVCLRLQYPEMAKHFSKILLMAGVKECSVEIKPTCSSSPCVHLTGPRCEVETLESYLQCVVTRHLEVKGPGVQQFFQGDGATTLRSVKSSCQVEILPTDVPENTISSSASSTNHSMDYDNILHIKVVVGLEQQQADVFVVPMVNTNMTSTLIGSSLLNKAGQQLQTNFNTAKGNRTLKSGEVLEVDAPQGLGCSKVLFLECAPQGINHNCENALRCGLGQIFALCERNLWGSVALPIIEPEDVLSIPVRDSVNILTQQISTFLSKSTHFLHTIRIPIMPNYSHSEEMFQIVLGTLHALMVDSTGQALFHSLTTDLDEVIMAVDRIKLHLVFGDITDEMTDAIVNTTDFNDFQTNGACKDILTKAGPSVQSLLKGASVAWRQIFTTPPGGLPCKIIMHVCGERSPSVIKTLAKEIVVQCEHGRYQSVAIPAICAGQGGLDPKVVAKSILEGVKEGVQGANLQYLKNIRIILLKINVFLAFKTVARQVFGASTQMTAPAPLHLSRSQAPSSPVCYDLSSLLASLPVTEDKAAFLVIGDRDKDVFDACTELQRAYDSQCLKESFYSDEMERLTKDELNQLRTKVHSLHLQLEINSSGKWVAKGLKDGVNEVARLMRDALRRQVREKEQDNLFTQVAWCILGPRSIWQKVPKKANHQLERADVNDGIVDAQGVKWTVDLRKLEATECDSGQVTALKRLENLSDFSFPIHWDSMNQKGLKVVALDPQSAEYKTVKADFQRTVLKTVLKIERIQNINLRRLYEARKSELEIKNDPAVGAGEKILYHGSAQASCSSIMSTNFNRNFAGQNGTVYGQGTYFAVNASYSANVNYAVPAADGTQQMFVARVLTGHYTMGFGDMRTAPVRVVPDQFYDSVVDYTQNPTMFVVFHDCQAYPDYLITFK", "length": 1205, "header": "tr|A0A8M9PQI2-1|A0A8M9PQI2_DANRE Isoform 1 of Poly [ADP-ribose] polymerase OS=Danio rerio OX=7955 GN=si:ch211-163c2.3 PE=3 SV=3 CANONICAL=A0A8M9PQI2-1" }, "locus": {} }, { "isoform_ac": "A0AC58G305-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI2/entry#A0AC58G305-1", "sequence": { "sequence": "MENYLYDVFFKASNLSDVALKHIKRYFEVRYRECVISNEGNDIYKISFANKNEQKNVLDQRDHFINIPGQRTVRVKASANQTCVAVVEQHNQVDRNLESSSSMQEQQQVQQTFPVSEKHFALIKEQFELYKNSDLPTLQIEQEPDVILLKGPKTEVLKCYQKLSTLKQGIIENRLSNYAFMNFLVSSDSINHLQKRFKQSLKSPVMIEISGSDLLLLSLSDGALKEAANAIETDLCSETIHLKKSSDFATLAFELSNAVKQANRESVKVELKYQNDSNSDTEVQLVGFTTKVTELMNILLEYKKKHRKHHVCLRLQYPEMAKHFSKILLMAGVKECSVEIKPTCSSSPCVHLTGPRCEVETLESYLQCVVTRHLEVKGPGVQQFFQGDGATTLRSVKSSCQVEILPTDVPENTISSSASSTNHSMDYDNILHIKVVVGLEQQQADVFVVPMVNTNMTSTLIGSSLLNKAGQQLQTNFNTAKGNRTLKSGEVLEVDAPQGLGCSKVLFLECAPQGINHNCENALRCGLGQIFALCERNLWGSVALPIIEPEDVLSIPVRDSVNILTQQISTFLSKSTHFLHTIRIPIMPNYSHSEEMFQIVLGTLHALMVDSTGQALFHSLTTDLDEVIMAVDRIKLHLVFGDITDEMTDAIVNTTDFNDFQTNGACKDILTKAGPSVQSLLKGGQGGLDPKVVAKSILEGVKEGVQGANLQYLKNIRIILLKINVFLAFKTVARQVFGASTQMTAPAPLHLSRSQAPSSPVCYDLSSLLASLPVTEDKAAFLVIGDRDKDVFDACTELQRAYDSQCLKESFYSDEMERLTKDELNQLRTKVHSLHLQLEINSSGKWVAKGLKDGVNEVARLMRDALRRQVREKEQDNLFTQVAWCILGPRSIWQKVPKKANHQLERADVNDGIVDAQGVKWTVDLRKLEATECDSGQVTALKRLENLSDFSFPIHWDSMNQKGLKVVALDPQSAEYKTVKADFQRTVLKTVLKIERIQNINLRRLYEARKSELEIKNDPAVGAGEKILYHGSAQASCSSIMSTNFNRNFAGQNGTVYGQGTYFAVNASYSANVNYAVPAADGTQQMFVARVLTGHYTMGFGDMRTAPVRVVPDQFYDSVVDYTQNPTMFVVFHDCQAYPDYLITFK", 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"total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PQI5-1", "uniprot_ac": "A0A8M9PQI5", "uniprot_id": "A0A8M9PQI5_DANRE", "mass": { "chemical_mass": 94633.0, "monoisotopic_mass": 94633.0 }, "refseq": { "ac": "XP_021333792", "name": "GTPase IMAP family member 8-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333792" }, "gene_names": [ { "name": "LOC110439974", "type": "recommended", "evidence": [ { "id": "A0A8M9PQI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI5" } ] }, { "name": "LOC110439974", "type": "synonym", "evidence": [ { "id": "XP_021333792", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333792" } ] } ], "protein_names": [ { "name": "GTPase IMAP family member 8-like", "type": "synonym", "evidence": [ { "id": "XP_021333792", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333792" }, { "id": "A0A8M9PQI5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021333792.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021333792", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021333792" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQI5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110439974", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQI5", "locus": {} } ], "crossref": [ { "id": "A0A8M9PQI5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PQI5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01852", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01852", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110439974", "url": 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"o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PQK6-1", "uniprot_ac": "A0A8M9PQK6", "uniprot_id": "A0A8M9PQK6_DANRE", "mass": { "chemical_mass": 91969.0, "monoisotopic_mass": 91969.0 }, "refseq": { "ac": "NP_001027013", "name": "follistatin-related protein 4 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027013" }, "gene_names": [ { "name": "fstl4", "type": "recommended", "evidence": [ { "id": "A0A8M9PQK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" } ] }, { "name": "drMahya-2", "type": "synonym", "evidence": [ { "id": "NP_001027013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027013" }, { "id": "A0A8M9PQK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" } ] }, { "name": "fstl4", "type": "synonym", "evidence": [ { "id": "NP_001027013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027013" } ] } ], "protein_names": [ { "name": "Follistatin-related protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PQK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6/entry#names_and_taxonomy" } ] }, { "name": "Follistatin-related protein 4 precursor", "type": "synonym", "evidence": [ { "id": "A0A8M9PQK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6/entry#names_and_taxonomy" } ] }, { "name": "follistatin-related protein 4 precursor", "type": "synonym", "evidence": [ { "id": "NP_001027013", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027013" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01010844.1, SRR32588732.21197573.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476729, SAMEA4476737 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On or before Aug 14, 2023 this sequence version replaced XP_021324572.1, NP_001027013.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001027013", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027013" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fstl4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070127-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070127-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00096", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00096", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00104", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00104", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd05736", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05736", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "571664", "url": "https://www.ncbi.nlm.nih.gov/gene/571664", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003598", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003598", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050653", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050653", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:571664", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571664", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RYLPVCG", "url": "https://omabrowser.org/oma/group/RYLPVCG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PQK6", "url": "https://www.orthodb.org/?gene=A0A8M9PQK6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10913", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10913", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10913:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10913:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07648", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07648", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13202", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13202", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13927", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13927", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001027013", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001027013", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PQK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070127-3", "url": "https://zfin.org/ZDB-GENE-070127-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGCLGLWVLSVLLGASLWLVNGAAAGTTAKELQEGLQDTKHGEPENKVKQNAAVCQRSSCGRGRECVVRAATGRAECVCQERCHSTFVPVCGSDGRFYQNHCELYRSACVRRRTISALHSKHCFLRGDACTMAEYNKLKSILMDMQPQSSTNAENSMAQRRTLVLNMFTYFDRNQDGRVSSEELAEISVKEHLENVLLECSMQDLLRYDDYNNDGHLTLQELYTAFQVIELSLAEDRRLSVSTVTVGLSVVLSCAVQGSLRPPIIWKRNGIILNFLDLEDINDFGDDGSLYITKVTTIHMGNYSCHAHGYEELSQTHLLQVNVPPVILVYPETQAQEPGVAASLRCHADGVPNPKLTWLKNGMDLQPHGSKQISLLANGSELHISSVRYEDTGAYTCIARNEVGVDEDISSLFVEDSARKTLANILWREEGLSVGNMFYVFSNEGITVLQPGNCEIRRHITHTERILGTHEELCPRISGVSSQECVWSSAVSVREKYVFVSQPLLNRLLVMDTQAQRVVQAVETDAMPVKLFYDKSHDQLWVLSWRDLLKSRSTLQVITSASTAAEQRQIIRTQFERVQDFYIPPTNLIITHVRFGFVYLKSEPAVHKVDLETLRVVKSISLQNFSCFPLSMAYTHLSGYYFIECQSEKRPTFQLLIDAVSDAIIGRNPNIHGQPFISPNGRFVVSVDKQRGKLQVQSVSISGELQIHYEADAKMSIADLEFQPSFTDANEFTAVVSSARGSKVLFLDLATGRIKTIGNVKNPVPASSWPWGDANRMVISSGVFGRYLLTSSADSMFILDGKQSAFHCEVSDVKFGNTAVWVGEV", "length": 825, "header": "tr|A0A8M9PQK6-1|A0A8M9PQK6_DANRE Isoform 1 of Follistatin-related protein 4 precursor OS=Danio rerio OX=7955 GN=fstl4 PE=4 SV=1 CANONICAL=A0A8M9PQK6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PQK6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6/entry#A0A8M9PQK6-1", "sequence": { "sequence": "MGCLGLWVLSVLLGASLWLVNGAAAGTTAKELQEGLQDTKHGEPENKVKQNAAVCQRSSCGRGRECVVRAATGRAECVCQERCHSTFVPVCGSDGRFYQNHCELYRSACVRRRTISALHSKHCFLRGDACTMAEYNKLKSILMDMQPQSSTNAENSMAQRRTLVLNMFTYFDRNQDGRVSSEELAEISVKEHLENVLLECSMQDLLRYDDYNNDGHLTLQELYTAFQVIELSLAEDRRLSVSTVTVGLSVVLSCAVQGSLRPPIIWKRNGIILNFLDLEDINDFGDDGSLYITKVTTIHMGNYSCHAHGYEELSQTHLLQVNVPPVILVYPETQAQEPGVAASLRCHADGVPNPKLTWLKNGMDLQPHGSKQISLLANGSELHISSVRYEDTGAYTCIARNEVGVDEDISSLFVEDSARKTLANILWREEGLSVGNMFYVFSNEGITVLQPGNCEIRRHITHTERILGTHEELCPRISGVSSQECVWSSAVSVREKYVFVSQPLLNRLLVMDTQAQRVVQAVETDAMPVKLFYDKSHDQLWVLSWRDLLKSRSTLQVITSASTAAEQRQIIRTQFERVQDFYIPPTNLIITHVRFGFVYLKSEPAVHKVDLETLRVVKSISLQNFSCFPLSMAYTHLSGYYFIECQSEKRPTFQLLIDAVSDAIIGRNPNIHGQPFISPNGRFVVSVDKQRGKLQVQSVSISGELQIHYEADAKMSIADLEFQPSFTDANEFTAVVSSARGSKVLFLDLATGRIKTIGNVKNPVPASSWPWGDANRMVISSGVFGRYLLTSSADSMFILDGKQSAFHCEVSDVKFGNTAVWVGEV", "length": 825, "header": "tr|A0A8M9PQK6-1|A0A8M9PQK6_DANRE Isoform 1 of Follistatin-related protein 4 precursor OS=Danio rerio OX=7955 GN=fstl4 PE=4 SV=1 CANONICAL=A0A8M9PQK6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Conservation of novel Mahya genes shows the existence of neural functions common between Hymenoptera and Deuterostome.", "journal": "Dev. Genes Evol.", "date": "2005", "authors": "Tsuchimoto Mayumi, Yasuo Shinobu, Funada Masahiro, Aoki Makoto, Sasagawa Hiromi, Yoshimura Takashi, Tadauchi Osamu, Cameron Sydney A, Kitagawa Yasuo, Kadowaki Tatsuhiko", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" } ], "reference": [ { "type": "PubMed", "id": "16193321", "url": "https://glygen.org/publication/PubMed/16193321" } ] }, { "title": "RING finger protein 121 facilitates the degradation and membrane localization of voltage-gated sodium channels.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2015", "authors": "Ogino Kazutoyo, Low Sean E, Yamada Kenta, Saint-Amant Louis, Zhou Weibin, Muto Akira, Asakawa Kazuhide, Nakai Junichi, Kawakami Koichi, Kuwada John Y, Hirata Hiromi", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" } ], "reference": [ { "type": "PubMed", "id": "25691753", "url": "https://glygen.org/publication/PubMed/25691753" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Single-cell mapping of gene expression landscapes and lineage in the zebrafish embryo.", "journal": "Science", "date": "2018", "authors": "Wagner Daniel E, Weinreb Caleb, Collins Zach M, Briggs James A, Megason Sean G, Klein Allon M", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" } ], "reference": [ { "type": "PubMed", "id": "29700229", "url": "https://glygen.org/publication/PubMed/29700229" } ] } ], "pathway": [ { "id": "dre:571664", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571664", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZJ81-1", "protein_name": "Follistatin-like 4", "gene_name": "Fstl4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPGGFWPHLALLGVSLPAVLGWMDQGASRSPNVVLGQSQTEETRGFEVTRREGLPSPGLSSSCGKKLCSHGSRCLHNRTTGQPLCHCLEVCRPRYMPVCGSDGKLYGNHCELRRAACLLGKRIVSVHSKDCFLKGDMCTVAGYARLKNVLLALQSRRQPLQQETHRQSLASQKRLLVESLFKALDTDGNGRLGSLELAQYVLKEQDMDGSLNRCSPGDLLRFDDYNSDGSLTLGEFYTAFQVIQLSLAPEDKVSVTTVTVGLSTVLTCAIRGDLRPPIIWKRNGLTLSFLGLEDINDFGEDDSLYITKVTTIHMGNYTCHALGHEQLFQTHVLQVNVPPVIRVYPETQAQEPGVAASLRCHAEGIPLPRIVWLKNGMDVSTQMSKQLSLLANGSELHIRSVRYEDTGAYTCIAKNEVGVDEDISSLFIEDSARKTRLSVGNMFYVFSDDGIVVIHPVDCEVQRRFKPTEKIFMSYEEICPRVEGDTTQPCQWASAVNVRNRYIYVAQPALNRVLVVDVQAQKVLQSIGVDPLPAKLSYDKSHDQVWVLSWGDMHKSQPSLQVITEASTGQGQHLIRTPFAGVDNFFIPPTNLIINHIRFGFIFNKTDPAVHKVDLETLMSLKTISLQHYGCMPQAMAHTHLGGYFFVQCRQDTPTSTGPQLLIDSVTDSVLGPNSDITGTPHVSPDGRFIVSVSNKGPWLHVQEVTVRGEIQTLYDLKINPGISDLAFQHSFTEGNQYNAYATLDKEPDLLFLELSTGKMGRLKNLKEPSRGPAPPWGGPRRVLRDSGLFGQYLLTAAQDSLFLVNGRQNALRCEVSGIKGAATVVWVGEV", "length": 832 }, "evidence": [ { "id": "HGNC:21389", "url": "https://alliancegenome.org/gene/HGNC:21389#orthology", "database": "AGR" }, { "id": "MGI:2443199", "url": "https://alliancegenome.org/gene/MGI:2443199#orthology", "database": "AGR" }, { "id": "RGD:1307227", "url": "https://alliancegenome.org/gene/RGD:1307227#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070127-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070127-3#orthology", "database": "AGR" }, { "id": "A0A8M9PQK6", "url": "https://omabrowser.org/oma/group/A0A8M9PQK6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MER8-1", "protein_name": "Follistatin like 4", "gene_name": "FSTL4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRPGGFWLHLTLLGASLPAALGWMNPGASGGWNVGVGESPAEESRSLDVRRREGLSSHDELPASCGKKLCGRGSRCMLNRETGEPECRCLEACRPSYVPVCGSDGRVYENHCELHRAACLLGKKIVMVRNKDCFLKGDPCTVADYARLKKVLLALQSRLQPLHEGDSRQDPASQKRLLVESLFKDFDADGDGHLGTSELAQHMLKEQDLEEDFLGCSPGDLLRFDDYNKDGLLTLHEFYTAFQVVQLSLAPEERVSVATVTVGLSTVLTCAIRGDLRPPIVWKRNGLALNFLDLEDINDFGEDDSLYITKVTTIHMGNYTCHASGHEQLFQTHVLQVNVPPVIRVYPETQAQEPGVAASLRCHAEGIPMPRITWLKNGMDVSTQMSKQLSLLANGSELHIGSVRYEDTGAYTCIAKNEVGVDEDISSLFIEDSARKTLANILWREEGLSVGNMFYVFSDDGIIVLHPVDCEIQRHLKPTEKIFMSYEEICPQKDGDATQPCQWASAVNVRHHYIYVAQPTLSRVLVVDVQAQKVLQSIGVDPLPAKLSYDKSHDQVWVLSWGNVHKSQPSLQVITEASTGQGQRLIRTPFAGVDDFFIPPTNLIINHIRFGFIFNKSDPAIHKVDLETLMPLKTIKLQSHGCLPQAMAHTHLGGYFFVQCRQDSSSEASPQLLIDSVTDTVVGPNGQVTGTPHTSPDGRFVVSAAPGSPQLHVQEISLRGEIRTLYNLKVSPGVSDVAFQRSFTQGDQYHVYATLETEPDLLFLELSTGKMGVLKGLKEPAPAGPARAWAGPRRIVRDSGLFGQHLLTPARESLFLINGRQNALRCEVAGVKGGTTVVWVGEV", "length": 843 }, "evidence": [ { "id": "A0A8M9PQK6", "url": "https://omabrowser.org/oma/group/A0A8M9PQK6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5STE3-1", "protein_name": "Follistatin-related protein 4", "gene_name": "Fstl4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPGGFWPHLALLGVSLPAVLGWMDQGASRSPNMVPGESQAEETRGFEVTRREGLPSPGLSASCGKKLCSHGSRCLLNRTTGQPSCQCLEVCRPRYMPVCGSDGRLYGNHCELRRAACLLGKRIVSVHSKDCFLKGDMCTMAGYARLKNVLLALQSRRQPLPQGTPRQSLASQKRLLVESLFKDLDADGNGHLGSLELAQYVLKEQDMDGSLNRCSPSDLLRFDDYNSDGSLTLGEFYTAFQVIQLSLAPEDKVSVTTVTVGLSTVLTCAIRGDLRPPIIWKRNGLTLSFLGLEDINDFGEDGSLYITKVTTVHMGNYTCHALGHEQLVQTHVLQVNVPPVIRVYPETQAQEPGVAASLRCHAEGIPLPRIIWLKNGMDVSTQMSKQLSLLANGSELHIGSVRYEDTGAYTCIAKNEVGVDEDISSLFIEDSARKTLANILWREEGLSVGNMFYVFAEDGIVVIHPVDCEVQRRLKPTEKIFMSYEEICPRVEGDATQPCQWASAVNVRNRYIYVAQPALNRVLVVDVQAQKVLQSIGVDPLPVKLSYDKSHDQVWVLSWGDMHKSQPSLQVITEASTGQGQHLIRTPFAGVDNFFIPPTNLIINHIRFGFIFNKTDPAVHKVDLETLMALKTISLRHYGCMPQAMAHTHLGGYFFVQCQQDTPTSTGPQLLIDSVTDSVLGPNSDITGTPHVSPDGRFIVSVSNKGPWLHVQEVTVRGEIQTLYDLKINPGISDLAFQHSFTEGSQYNAYATLDKEPDLLFLELSTGKMGRLKNLKEPPRGPAPTWGGPRRVLRDSGLFGQYLLTPAQESLFLVNGRQNALRCEVSGIKGAATVVWVGEV", "length": 841 }, "evidence": [ { "id": "HGNC:21389", "url": "https://alliancegenome.org/gene/HGNC:21389#orthology", "database": "AGR" }, { "id": "MGI:2443199", "url": "https://alliancegenome.org/gene/MGI:2443199#orthology", "database": "AGR" }, { "id": "RGD:1307227", "url": "https://alliancegenome.org/gene/RGD:1307227#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070127-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070127-3#orthology", "database": "AGR" }, { "id": "A0A8M9PQK6", "url": "https://omabrowser.org/oma/group/A0A8M9PQK6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6MZW2-1", "protein_name": "Follistatin-related protein 4", "gene_name": "FSTL4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPGGFWLHLTLLGASLPAALGWMDPGTSRGPDVGVGESQAEEPRSFEVTRREGLSSHNELLASCGKKFCSRGSRCVLSRKTGEPECQCLEACRPSYVPVCGSDGRFYENHCKLHRAACLLGKRITVIHSKDCFLKGDTCTMAGYARLKNVLLALQTRLQPLQEGDSRQDPASQKRLLVESLFRDLDADGNGHLSSSELAQHVLKKQDLDEDLLGCSPGDLLRFDDYNSDSSLTLREFYMAFQVVQLSLAPEDRVSVTTVTVGLSTVLTCAVHGDLRPPIIWKRNGLTLNFLDLEDINDFGEDDSLYITKVTTIHMGNYTCHASGHEQLFQTHVLQVNVPPVIRVYPESQAQEPGVAASLRCHAEGIPMPRITWLKNGVDVSTQMSKQLSLLANGSELHISSVRYEDTGAYTCIAKNEVGVDEDISSLFIEDSARKTLANILWREEGLSVGNMFYVFSDDGIIVIHPVDCEIQRHLKPTEKIFMSYEEICPQREKNATQPCQWVSAVNVRNRYIYVAQPALSRVLVVDIQAQKVLQSIGVDPLPAKLSYDKSHDQVWVLSWGDVHKSRPSLQVITEASTGQSQHLIRTPFAGVDDFFIPPTNLIINHIRFGFIFNKSDPAVHKVDLETMMPLKTIGLHHHGCVPQAMAHTHLGGYFFIQCRQDSPASAARQLLVDSVTDSVLGPNGDVTGTPHTSPDGRFIVSAAADSPWLHVQEITVRGEIQTLYDLQINSGISDLAFQRSFTESNQYNIYAALHTEPDLLFLELSTGKVGMLKNLKEPPAGPAQPWGGTHRIMRDSGLFGQYLLTPARESLFLINGRQNTLRCEVSGIKGGTTVVWVGEV", "length": 842 }, "evidence": [ { "id": "HGNC:21389", "url": "https://alliancegenome.org/gene/HGNC:21389#orthology", "database": "AGR" }, { "id": "MGI:2443199", "url": "https://alliancegenome.org/gene/MGI:2443199#orthology", "database": "AGR" }, { "id": "RGD:1307227", "url": "https://alliancegenome.org/gene/RGD:1307227#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070127-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070127-3#orthology", "database": "AGR" }, { "id": "A0A8M9PQK6", "url": "https://omabrowser.org/oma/group/A0A8M9PQK6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell differentiation", "id": "GO:0030154", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030154", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" } ], "pmid": "" }, { "name": "regulation of BMP signaling pathway", "id": "GO:0030510", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030510", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQK6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 302, "end_pos": 304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PQK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 159, "end_pos": 194, "start_aa": "Gln", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PQK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 229, "end_pos": 322, "start_aa": "Ile", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8M9PQK6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQK6" }, { "id": "PS51465", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51465" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kazal-like", "eco_id": "ECO_0000259", "start_pos": 78, "end_pos": 125, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 302, "end_pos": 304 }, { "start_pos": 378, "end_pos": 380 }, { "start_pos": 624, "end_pos": 626 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8M9PQP2-1", "uniprot_ac": "A0A8M9PQP2", "uniprot_id": "A0A8M9PQP2_DANRE", "mass": { "chemical_mass": 71250.0, "monoisotopic_mass": 71250.0 }, "refseq": { "ac": "XP_021323445", "name": "uncharacterized protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323445" }, "gene_names": [ { "name": "LOC100150699", "type": "recommended", "evidence": [ { "id": "A0A8M9PQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQP2" } ] }, { "name": "LOC100150699", "type": "synonym", "evidence": [ { "id": "XP_021323445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323445" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQP2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021323445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323445" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323445.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323445" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQP2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQP2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100150699", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQP2", "locus": {} } ], "crossref": [ { "id": "cd11657", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11657", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100150699", "url": "https://www.ncbi.nlm.nih.gov/gene/100150699", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029400", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029400", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039098", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039098", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100150699", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100150699", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PQP2", "url": "https://www.orthodb.org/?gene=A0A8M9PQP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15512", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15512", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15512:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15512:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14973", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14973", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323445", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PQP2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HVL0", "url": "https://www.uniprot.org/uniprotkb/A0AC58HVL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HVL0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HVL0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MTVLDTETAAAFVGMSQNLWLEKACSILIPDLPLWIIEYAWTKRMMEVLEVLGPPLWLEGDWHHLSLEEPCRVRAVAAEVWRIVQTRDIQHFERVLEFLDVTYTLEPRLVTPIKHMKIKFGLQTLVIMWMLWNDESAANITVKMENFFPNKLPEYHKCRRKHVDLMQKNQKEFKSFAHVLARDRDMRETYIHDLMEEQYGERYAQKLEERLLHYLGELDKLLPQPTYIDQVLKQPHSYERGEKILKKLLSKDSASLATALKRLLHCAATTNLDLEERSTSSVPNTSEEQRDVKVEEPLLGTLHVILRPSQDNMTMDPLTQANSKELFGSQGLWKHKNSENILPQKEICSDRVTSTQLSGSETNEDNLSQSLVQRDLVGKHRLAKTQAEPEIKEAETGFTEQTCSRHGKKMKSILLECSEELDGDAVQVECTPTSTQSTPPFLPHTPQPQASPNQHSLSSHPDSSSTNISKVSRSPVSSTTPVSPSLLQQCCSPSQSTALEQLDTSRINEGPDLTPIVFAEPSRTIEPKLKLSIESQSFLIQSRWLQPQVCLHRINNEECARLMDSNGACDILEKEREAEDDEYILYDVNALYSDSYSDDSDSTDCDDPDYTPRGDKQRTSKKKC", "length": 624, "header": "tr|A0A8M9PQP2-1|A0A8M9PQP2_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100150699 PE=4 SV=2 CANONICAL=A0A8M9PQP2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PQP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQP2/entry#A0A8M9PQP2-1", "sequence": { "sequence": "MTVLDTETAAAFVGMSQNLWLEKACSILIPDLPLWIIEYAWTKRMMEVLEVLGPPLWLEGDWHHLSLEEPCRVRAVAAEVWRIVQTRDIQHFERVLEFLDVTYTLEPRLVTPIKHMKIKFGLQTLVIMWMLWNDESAANITVKMENFFPNKLPEYHKCRRKHVDLMQKNQKEFKSFAHVLARDRDMRETYIHDLMEEQYGERYAQKLEERLLHYLGELDKLLPQPTYIDQVLKQPHSYERGEKILKKLLSKDSASLATALKRLLHCAATTNLDLEERSTSSVPNTSEEQRDVKVEEPLLGTLHVILRPSQDNMTMDPLTQANSKELFGSQGLWKHKNSENILPQKEICSDRVTSTQLSGSETNEDNLSQSLVQRDLVGKHRLAKTQAEPEIKEAETGFTEQTCSRHGKKMKSILLECSEELDGDAVQVECTPTSTQSTPPFLPHTPQPQASPNQHSLSSHPDSSSTNISKVSRSPVSSTTPVSPSLLQQCCSPSQSTALEQLDTSRINEGPDLTPIVFAEPSRTIEPKLKLSIESQSFLIQSRWLQPQVCLHRINNEECARLMDSNGACDILEKEREAEDDEYILYDVNALYSDSYSDDSDSTDCDDPDYTPRGDKQRTSKKKC", "length": 624, "header": "tr|A0A8M9PQP2-1|A0A8M9PQP2_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC100150699 PE=4 SV=2 CANONICAL=A0A8M9PQP2-1" }, "locus": {} }, { "isoform_ac": "A0AC58HVL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQP2/entry#A0AC58HVL0-1", "sequence": { "sequence": "MTVLDTETAAAFVGMSQNLWLEKACSILIPDLPLWIIEYAWTKRMMEVLEVLGPPLWLEGDWHHLSLEEPCRVRAVAAEVWRIVQTRDIQHFERVLEFLDVTYTLEPRLVTPIKHMKIKFGLQTLVIMWMLWNDESAANITVKMENFFPNKLPEYHKCRRKHVDLMQKNQKEFKSFAHVLARDRDMRETYIHDLMEEQYGERYAQKLEERLLHYLGELDKLLPQPTYIDQVGSKPFEDRAR", "length": 241, "header": "tr|A0AC58HVL0-1|A0AC58HVL0_DANRE Computationally mapped isoform of TERF1-interacting nuclear factor 2 isoform X2 OS=Danio rerio OX=7955 GN=LOC100150699 PE=4 SV=1 CANONICAL=A0A8M9PQP2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100150699", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100150699", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "telomere capping", "id": "GO:0016233", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016233", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQP2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQP2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "shelterin complex", "id": "GO:0070187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070187", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQP2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQP2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 284, "end_pos": 286, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 467, "end_pos": 469, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PQP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQP2" }, { "id": "PF14973", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14973" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TERF1-interacting nuclear factor 2 N-terminal", "eco_id": "ECO_0000259", "start_pos": 81, "end_pos": 227, "start_aa": "Trp", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 139, "end_pos": 141 }, { "start_pos": 284, "end_pos": 286 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 366, "end_pos": 368 }, { "start_pos": 467, "end_pos": 469 } ] }, "class_list": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PQU8-1", "uniprot_ac": "A0A8M9PQU8", "uniprot_id": "A0A8M9PQU8_DANRE", "mass": { "chemical_mass": 18244.0, "monoisotopic_mass": 18244.0 }, "refseq": { "ac": "XP_021324661", "name": "calcium channel flower homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324661" }, "gene_names": [ { "name": "cacfd1", "type": "recommended", "evidence": [ { "id": "A0A8M9PQU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQU8" } ] }, { "name": "cacfd1", "type": "synonym", "evidence": [ { "id": "XP_021324661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324661" } ] } ], "protein_names": [ { "name": "Calcium channel flower homolog", "type": "synonym", "evidence": [ { "id": "A0A8M9PQU8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQU8/entry#names_and_taxonomy" } ] }, { "name": "calcium channel flower homolog", "type": "synonym", "evidence": [ { "id": "XP_021324661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324661" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324661" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQU8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQU8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cacfd1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQU8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120215-178", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-178", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100333889", "url": "https://www.ncbi.nlm.nih.gov/gene/100333889", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100333889", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333889", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CIELNTI", "url": "https://omabrowser.org/oma/group/CIELNTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PQU8", "url": "https://www.orthodb.org/?gene=A0A8M9PQU8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13314", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13314", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13314:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13314:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10233", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10233", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021324661", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324661", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PQU8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQU8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PQU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQU8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120215-178", "url": "https://zfin.org/ZDB-GENE-120215-178", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSTEEAEAPTKTATDEDGMSWWYRWICKLAGVLGGISCATMGVWNCVTVHPLNIAAGVWMVLTAFVLFLCEVPFCCQFVEFANAVAARADRLKPWQKALFYCGMALFPVFLSFSITTLVGNAIAFATGVLYGLASLGKKGDAVSYARLQHQKQGDEEKLAGTTEESVP", "length": 168, "header": "tr|A0A8M9PQU8-1|A0A8M9PQU8_DANRE Isoform 1 of Calcium channel flower homolog OS=Danio rerio OX=7955 GN=cacfd1 PE=3 SV=1 CANONICAL=A0A8M9PQU8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PQU8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQU8/entry#A0A8M9PQU8-1", "sequence": { "sequence": "MSTEEAEAPTKTATDEDGMSWWYRWICKLAGVLGGISCATMGVWNCVTVHPLNIAAGVWMVLTAFVLFLCEVPFCCQFVEFANAVAARADRLKPWQKALFYCGMALFPVFLSFSITTLVGNAIAFATGVLYGLASLGKKGDAVSYARLQHQKQGDEEKLAGTTEESVP", "length": 168, "header": "tr|A0A8M9PQU8-1|A0A8M9PQU8_DANRE Isoform 1 of Calcium channel flower homolog OS=Danio rerio OX=7955 GN=cacfd1 PE=3 SV=1 CANONICAL=A0A8M9PQU8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100333889", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100333889", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PHF8-1", "protein_name": "Calcium channel flower domain containing 1", "gene_name": "CACFD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSSQDEQFQAAAPESASSSADDGMTWWYRWLCRIAGVIGGVSCAVAGLWNCVTINPLNIAAGVWMMLNAFVLFLCEAPFCCQFIEFANAVSARADKLRAWQKAAFYCGMAVFPVMLSLTLTTLFGNAIAFATGVLYGLSALGKKGDAISYARIHQQQKQMDEEKLTGCLEGQAL", "length": 174 }, "evidence": [ { "id": "A0A8M9PQU8", "url": "https://omabrowser.org/oma/group/A0A8M9PQU8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4A9I3-1", "protein_name": "Calcium channel flower homolog", "gene_name": "Cacfd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGSVAAGAAAGPVPPAQEEGMTWWYRWLCRLAGVLGAVSCAISGLFNCVTIHPLNIAAGVWMIMNAFILLLCEAPFCCQFVEFANTVAEKVDRLRSWQKAVFYCGMAIVPIVMSLTLTTLLGNAIAFATGVLYGLSALGKKGDAISYARIQQQRQQADEEKLAETFEGEL", "length": 171 }, "evidence": [ { "id": "RGD:1311501", "url": "https://alliancegenome.org/gene/RGD:1311501#orthology", "database": "AGR" }, { "id": "HGNC:1365", "url": "https://alliancegenome.org/gene/HGNC:1365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-178", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-178#orthology", "database": "AGR" }, { "id": "MGI:1924317", "url": "https://alliancegenome.org/gene/MGI:1924317#orthology", "database": "AGR" }, { "id": "FB:FBgn0261722", "url": "https://alliancegenome.org/gene/FB:FBgn0261722#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BG21-1", "protein_name": "Calcium channel flower homolog", "gene_name": "Cacfd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGSGAAGAAAGPAPPAQEEGMTWWYRWLCRLAGVLGAVSCAISGLFNCVTIHPLNIAAGVWMIMNAFILLLCEAPFCCQFVEFANTVAEKVDRLRSWQKAVFYCGMAIVPIVMSLTLTTLLGNAIAFATGVLYGLSALGKKGDAISYARIQQQRQQADEEKLAETFEGEL", "length": 171 }, "evidence": [ { "id": "RGD:1311501", "url": "https://alliancegenome.org/gene/RGD:1311501#orthology", "database": "AGR" }, { "id": "HGNC:1365", "url": "https://alliancegenome.org/gene/HGNC:1365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-178", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-178#orthology", "database": "AGR" }, { "id": "MGI:1924317", "url": "https://alliancegenome.org/gene/MGI:1924317#orthology", "database": "AGR" }, { "id": "FB:FBgn0261722", "url": "https://alliancegenome.org/gene/FB:FBgn0261722#orthology", "database": "AGR" }, { "id": "A0A8M9PQU8", "url": "https://omabrowser.org/oma/group/A0A8M9PQU8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q95T12-1", "protein_name": "Calcium channel flower", "gene_name": "fwe", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSFAEKITGLLARPNQQDPIGPEQPWYLKYGSRLLGIVAAFFAILFGLWNVFSIITLSVSCLVAGILQMVAGFVVMLLEAPCCFVCFGQVNEIAEKVESKPLYFRAGLYIAMAIPPIILCFGLASLFGSGLIFGTGVVYGMMALGKKASAEDMRAAAQQTFGGNTPAQTNDRAGIVNNAQPFSFTGAVGTDSNV", "length": 194 }, "evidence": [ { "id": "RGD:1311501", "url": "https://alliancegenome.org/gene/RGD:1311501#orthology", "database": "AGR" }, { "id": "HGNC:1365", "url": "https://alliancegenome.org/gene/HGNC:1365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-178", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-178#orthology", "database": "AGR" }, { "id": "MGI:1924317", "url": "https://alliancegenome.org/gene/MGI:1924317#orthology", "database": "AGR" }, { "id": "FB:FBgn0261722", "url": "https://alliancegenome.org/gene/FB:FBgn0261722#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9UGQ2-1", "protein_name": "Calcium channel flower homolog", "gene_name": "CACFD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSSGGAPGASASSAPPAQEEGMTWWYRWLCRLSGVLGAVSCAISGLFNCITIHPLNIAAGVWMIMNAFILLLCEAPFCCQFIEFANTVAEKVDRLRSWQKAVFYCGMAVVPIVISLTLTTLLGNAIAFATGVLYGLSALGKKGDAISYARIQQQRQQADEEKLAETLEGEL", "length": 172 }, "evidence": [ { "id": "RGD:1311501", "url": "https://alliancegenome.org/gene/RGD:1311501#orthology", "database": "AGR" }, { "id": "HGNC:1365", "url": "https://alliancegenome.org/gene/HGNC:1365#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-178", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-178#orthology", "database": "AGR" }, { "id": "MGI:1924317", "url": "https://alliancegenome.org/gene/MGI:1924317#orthology", "database": "AGR" }, { "id": "FB:FBgn0261722", "url": "https://alliancegenome.org/gene/FB:FBgn0261722#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PQU8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PQU8" } ], "pmid": "" }, { "name": "endomembrane system", "id": "GO:0012505", "url": 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This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021324856.1. 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Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. 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10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021334117", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334117" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRF0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRF0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC110440013", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRF0", "locus": {} } ], "crossref": [ { "id": "A0A8M9PRF0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PRF0", "database": "AlphaFoldDB", "categories": [] }, { "id": "101884444", "url": "https://www.ncbi.nlm.nih.gov/gene/101884444", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "110440013", "url": 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"categories": [ "Protein" ] }, { "id": "A0A8M9PRF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRF0-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTLDEDVRDAVLAVLPGLSEEKLVSLLNKLASIGVESKSDLQFVKEDDLPDHITPIQCRRLLNAWNIEDKTVCAKVSPLESTNIVFDVSPVNSPSSNFSSSCTPSVSSTNSSSSTVDLTVWPENFEVPWNRMSSGIKTATALGRRPTAKERREMVRIIVDEMRQTELNPSKSQCLIVAKKIVKQYPQSFADVLKDGTRIGTGYGSLLIQLKTRVEHVNRGCSFSRRRKQKKTSNSPPEDTGPGPTDQYGCVRWQPECPVDDTEESLQEKQEEMKDLYSCEGPAGAQKGHLSQLMKATYYLQRKSINACPPPSIAELKNEWPYLFTPKELYSHFKSLTNISILERLEKSMEEKGKMILQFFRQKPAGTKTDEIQRILLKFDDSGASSFIPCVVLVLLSHFKEKNDALILQTDVSATAGDVEKSLVLPDSPRLIVLGDILTATQWMLSIEGQVVVGPHPNFIAGFAALFSSYYNFNLVYQEQASCTLEFVQRCFVGINPPTGTKAATAKIGGKKGGKVSEKRNHTVNPHVCTLLRKLMDFEWLSM", "length": 544, "header": "tr|A0A8M9PRF0-1|A0A8M9PRF0_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC110440013 PE=4 SV=1 CANONICAL=A0A8M9PRF0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PRF0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRF0/entry#A0A8M9PRF0-1", "sequence": { "sequence": "MSTLDEDVRDAVLAVLPGLSEEKLVSLLNKLASIGVESKSDLQFVKEDDLPDHITPIQCRRLLNAWNIEDKTVCAKVSPLESTNIVFDVSPVNSPSSNFSSSCTPSVSSTNSSSSTVDLTVWPENFEVPWNRMSSGIKTATALGRRPTAKERREMVRIIVDEMRQTELNPSKSQCLIVAKKIVKQYPQSFADVLKDGTRIGTGYGSLLIQLKTRVEHVNRGCSFSRRRKQKKTSNSPPEDTGPGPTDQYGCVRWQPECPVDDTEESLQEKQEEMKDLYSCEGPAGAQKGHLSQLMKATYYLQRKSINACPPPSIAELKNEWPYLFTPKELYSHFKSLTNISILERLEKSMEEKGKMILQFFRQKPAGTKTDEIQRILLKFDDSGASSFIPCVVLVLLSHFKEKNDALILQTDVSATAGDVEKSLVLPDSPRLIVLGDILTATQWMLSIEGQVVVGPHPNFIAGFAALFSSYYNFNLVYQEQASCTLEFVQRCFVGINPPTGTKAATAKIGGKKGGKVSEKRNHTVNPHVCTLLRKLMDFEWLSM", "length": 544, "header": "tr|A0A8M9PRF0-1|A0A8M9PRF0_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC110440013 PE=4 SV=1 CANONICAL=A0A8M9PRF0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 246, "start_aa": "Thr", "end_pos": 246, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr246", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:110440013", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110440013", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 339, "end_pos": 341, "annotation": "n_glycosylation_sequon" }, { "start_pos": 522, "end_pos": 524, "annotation": "n_glycosylation_sequon" }, { "start_pos": 98, "end_pos": 100, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 246 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 339, "end_pos": 341 }, { "start_pos": 522, "end_pos": 524 }, { "start_pos": 98, "end_pos": 100 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PRK3-1", "uniprot_ac": "A0A8M9PRK3", "uniprot_id": "A0A8M9PRK3_DANRE", "mass": { "chemical_mass": 106301.0, "monoisotopic_mass": 106301.0 }, "refseq": { "ac": "XP_021334172", "name": "LOW QUALITY PROTEIN: NLR family CARD domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334172" }, "gene_names": [ { "name": "LOC101886147", "type": "recommended", "evidence": [ { "id": "A0A8M9PRK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRK3" } ] }, { "name": "LOC101886147", "type": "synonym", "evidence": [ { "id": "XP_021334172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334172" } ] } ], "protein_names": [ { "name": "LOW QUALITY PROTEIN: NLR family CARD domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "XP_021334172", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334172" }, { "id": "A0A8M9PRK3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRK3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## frameshifts :: corrected 1 indel ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021334172.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021334172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334172" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRK3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101886147", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRK3", "locus": {} } ], "crossref": [ { "id": "A0A8M9PRK3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PRK3", "database": "AlphaFoldDB", "categories": [] }, { "id": "101886147", "url": "https://www.ncbi.nlm.nih.gov/gene/101886147", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101886147", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886147", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PRK3", "url": "https://www.orthodb.org/?gene=A0A8M9PRK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021334172", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334172", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PRK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRK3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSRRSREQDTRMDNRESPAPSCVSMKSHQSIDDVINFSSDLSLNDRESPAPSCVSIKSHQSIDDIIDFSSGDSTDPRKRNKNKEDERQSIFAFAQRKMNQADLSNTRQTKLGPVCLQQHKSRLGEKFQRLHEGIAYQGNLTLLNEIYTELFITKGNSGEVNKEHEVRQIEMSRWPDMQEIPIRCNDIFKASPGVFKSIRSVLTRGVAGIGKTVSVQKFILDWAEGKANQDVHLIFPLPFRELNLMKDEEISLMGLLHQFFSDIKELSTSFLYDYRVMFIFDGLDECRLPLNFQSNQSLSDVTHCASADVLLTNLIQGTLLPSALIWITSRPAAASQIPPECVDQLTEVRGFSDLQKEQYFRKKIQDQSLANRIIPYIKSSRSLHIMCHIPVFCWISATVLERLLSEAESAEIPRTLTQMFTHFLIVQTKLKSQKYDDNRKVDLQQVRKSICSLGKLAFEQLKVGNLIFYEEDLDKCGIDVREVLVYSGVCTQIFREESGLCLGKVYSFVHLSIQEFLAALFKFLSFVSDMKHESEITNLLKKEVDRALQSENGHMDLFLRFLLGLSLESSQNLLRGILTRTVNTSQSCLELAEYIKEKIRDDQFPEKSINLFHCLNELNDHSLEQEVQTYLKGSRANRLAEVSLSPAEWSALVFVLLNSEEEMNEFELSKYHQSEETLLRLMPVVKVCRKANLSGCFLTWKICSALADALRGLRVLNLSHNNLQDSGLKLLSAGLKNYTCKLETLELYNCSIGEEGFAALASALRSNPSHLRELDLSWNHPGVSGVKFLSDLLKDPQFNLKKLQMYRCNIGEEGFAFLASALRSNPSHIRELNLSSNKPGTSGVKLISVLLEDPQCKLHKLQLSDCGIEEEGCAALASALRSNPLHLKELNLSSNKLGDSGLKLLNDLLKDPHCTLVTLNFLPYLPSHTCKTKLSTRF", "length": 939, "header": "tr|A0A8M9PRK3-1|A0A8M9PRK3_DANRE Isoform 1 of LOW QUALITY PROTEIN: NLR family CARD domain-containing protein 3 OS=Danio rerio OX=7955 GN=LOC101886147 PE=4 SV=2 CANONICAL=A0A8M9PRK3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PRK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRK3/entry#A0A8M9PRK3-1", "sequence": { "sequence": "MSSRRSREQDTRMDNRESPAPSCVSMKSHQSIDDVINFSSDLSLNDRESPAPSCVSIKSHQSIDDIIDFSSGDSTDPRKRNKNKEDERQSIFAFAQRKMNQADLSNTRQTKLGPVCLQQHKSRLGEKFQRLHEGIAYQGNLTLLNEIYTELFITKGNSGEVNKEHEVRQIEMSRWPDMQEIPIRCNDIFKASPGVFKSIRSVLTRGVAGIGKTVSVQKFILDWAEGKANQDVHLIFPLPFRELNLMKDEEISLMGLLHQFFSDIKELSTSFLYDYRVMFIFDGLDECRLPLNFQSNQSLSDVTHCASADVLLTNLIQGTLLPSALIWITSRPAAASQIPPECVDQLTEVRGFSDLQKEQYFRKKIQDQSLANRIIPYIKSSRSLHIMCHIPVFCWISATVLERLLSEAESAEIPRTLTQMFTHFLIVQTKLKSQKYDDNRKVDLQQVRKSICSLGKLAFEQLKVGNLIFYEEDLDKCGIDVREVLVYSGVCTQIFREESGLCLGKVYSFVHLSIQEFLAALFKFLSFVSDMKHESEITNLLKKEVDRALQSENGHMDLFLRFLLGLSLESSQNLLRGILTRTVNTSQSCLELAEYIKEKIRDDQFPEKSINLFHCLNELNDHSLEQEVQTYLKGSRANRLAEVSLSPAEWSALVFVLLNSEEEMNEFELSKYHQSEETLLRLMPVVKVCRKANLSGCFLTWKICSALADALRGLRVLNLSHNNLQDSGLKLLSAGLKNYTCKLETLELYNCSIGEEGFAALASALRSNPSHLRELDLSWNHPGVSGVKFLSDLLKDPQFNLKKLQMYRCNIGEEGFAFLASALRSNPSHIRELNLSSNKPGTSGVKLISVLLEDPQCKLHKLQLSDCGIEEEGCAALASALRSNPLHLKELNLSSNKLGDSGLKLLNDLLKDPHCTLVTLNFLPYLPSHTCKTKLSTRF", "length": 939, "header": "tr|A0A8M9PRK3-1|A0A8M9PRK3_DANRE Isoform 1 of LOW QUALITY PROTEIN: NLR family CARD domain-containing protein 3 OS=Danio rerio OX=7955 GN=LOC101886147 PE=4 SV=2 CANONICAL=A0A8M9PRK3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101886147", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886147", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRK3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRK3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRK3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 584, "end_pos": 586, "annotation": "n_glycosylation_sequon" }, { "start_pos": 693, "end_pos": 695, "annotation": "n_glycosylation_sequon" }, { "start_pos": 718, "end_pos": 720, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" }, { "start_pos": 750, "end_pos": 752, "annotation": "n_glycosylation_sequon" }, { "start_pos": 834, "end_pos": 836, "annotation": "n_glycosylation_sequon" }, { "start_pos": 892, "end_pos": 894, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021327559", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021327559" } ] }, { "annotation": "Somatostatin inhibits the release of somatotropin.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ6#function" }, { "database": "UniProtKB", "id": "ARBA00003524", "url": "https://www.uniprot.org/uniprotkb/ARBA00003524#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PRQ6", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sst5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ6", "locus": {} } ], 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"MPTSLQTPVFCRAERMFSRLQVVVVTLWVSLLLCRVSSAPRGDLLFQLLRSQVDPKENELQDLSRLLLLKQLSESVTPEEKDALDSIDELDVRNEVVRQIPVSQRERKAGCRNFYWKTFTSC", "length": 122, "header": "tr|A0A8M9PRQ6-1|A0A8M9PRQ6_DANRE Isoform 1 of Somatostatin-1 OS=Danio rerio OX=7955 GN=sst5 PE=3 SV=1 CANONICAL=A0A8M9PRQ6-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PRQ6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRQ6/entry#A0A8M9PRQ6-1", "sequence": { "sequence": "MPTSLQTPVFCRAERMFSRLQVVVVTLWVSLLLCRVSSAPRGDLLFQLLRSQVDPKENELQDLSRLLLLKQLSESVTPEEKDALDSIDELDVRNEVVRQIPVSQRERKAGCRNFYWKTFTSC", "length": 122, "header": "tr|A0A8M9PRQ6-1|A0A8M9PRQ6_DANRE Isoform 1 of Somatostatin-1 OS=Danio rerio OX=7955 GN=sst5 PE=3 SV=1 CANONICAL=A0A8M9PRQ6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:793347", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793347", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { 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"sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"name": "wu:fc17e01", "type": "synonym", "evidence": [ { "id": "NP_001073556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073556" }, { "id": "A1A5I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5I1" } ] }, { "name": "zgc:153800", "type": "synonym", "evidence": [ { "id": "NP_001073556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073556" }, { "id": "A1A5I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5I1" } ] } ], "protein_names": [ { "name": "Protein FAM133", "type": "recommended", "evidence": [ { "id": "A1A5I1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5I1/entry#names_and_taxonomy" } ] }, { "name": "protein FAM133", "type": "synonym", "evidence": [ { "id": "NP_001073556", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073556" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC128660.1, EH508741.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC128660.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001073556", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073556" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1A5I1", "url": "https://www.uniprot.org/uniprotkb/A1A5I1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam133", "url": "https://www.uniprot.org/uniprotkb/A1A5I1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-229", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-229", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A1A5I1", "url": "https://alphafold.ebi.ac.uk/entry/A1A5I1", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000013863", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000013863", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "790942", "url": "https://www.ncbi.nlm.nih.gov/gene/790942", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026766", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026766", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:790942", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:790942", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KTGHRRH", "url": "https://omabrowser.org/oma/group/KTGHRRH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A1A5I1", "url": "https://www.orthodb.org/?gene=A1A5I1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31911", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31911", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": 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"url": "https://zfin.org/ZDB-GENE-060503-229", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGKRDNRVAYLNPIAAARARGPAPTSGTTIQDYLSRPRPSWEEVKEQLEKKRKGSRALADFEDKMNARWKKELEKNREKVLGGGDKKEKEKEKDKEKEKKEKKKKEKKKSSRHSSSSSSSSSSSDSSSSSSSDAEDDDEKKNLKKKKKRKRSSTRKASDETDSESETDSRESFKKKRKKTDGEKDKDEKDSRKKRKAERSQSESSDESDVDKDADSKKKKHSSEEKEKITDKSKKKKKKKKHKKHSKKKKRKTSSSELD", "length": 259, "header": "sp|A1A5I1-1|F133_DANRE Isoform 1 of Protein FAM133 OS=Danio rerio OX=7955 GN=fam133 PE=2 SV=2 CANONICAL=A1A5I1-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PRU0-1", "url": "https://www.uniprot.org/uniprotkb/A1A5I1/entry#A0A8M9PRU0-1", "sequence": { "sequence": "MGKRDNRVAYLNPIAAARARGPAPTSGTTIQDYLSRPRPSWEEVKEQLEKKRKGSRALADFEDKMNARWKKELEKNREKVLGGGDKKEKEKEKDKEKEKKEKKKKEKKKSSRHSSSSSSSSSSSDSSSSSSSDAEDDDEKKNLKKKKKRKRSSTRKASDETDSESETDSRDEKDSRKKRKAERSQSESSDESDVDKDADSKKKKHSSEEKEKITDKSKKKKKKKKHKKHSKKKKRKTSSSELD", "length": 243, "header": "tr|A0A8M9PRU0-1|F133_DANRE Computationally mapped isoform of Protein FAM133 OS=Danio rerio OX=7955 GN=fam133 PE=2 SV=1 CANONICAL=A1A5I1-1" }, "locus": {} }, { "isoform_ac": "A1A5I1-1", "url": "https://www.uniprot.org/uniprotkb/A1A5I1/entry#A1A5I1-1", "sequence": { "sequence": "MGKRDNRVAYLNPIAAARARGPAPTSGTTIQDYLSRPRPSWEEVKEQLEKKRKGSRALADFEDKMNARWKKELEKNREKVLGGGDKKEKEKEKDKEKEKKEKKKKEKKKSSRHSSSSSSSSSSSDSSSSSSSDAEDDDEKKNLKKKKKRKRSSTRKASDETDSESETDSRESFKKKRKKTDGEKDKDEKDSRKKRKAERSQSESSDESDVDKDADSKKKKHSSEEKEKITDKSKKKKKKKKHKKHSKKKKRKTSSSELD", "length": 259, "header": "sp|A1A5I1-1|F133_DANRE Isoform 1 of Protein FAM133 OS=Danio rerio OX=7955 GN=fam133 PE=2 SV=2 CANONICAL=A1A5I1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 25, "start_aa": "Thr", "end_pos": 25, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr25", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths 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This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329812", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329812" } ] } ], "disease": [ { "disease_id": "DOID:2377", "recommended_name": { "id": "DOID:2377", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2377", "name": "multiple sclerosis", "description": "A demyelinating disease that involves damage to the fatty myelin sheaths around the axons of the brain and spinal cord resulting in demyelination and scarring." }, "synonyms": [ { "id": "DOID:2377", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2377", "name": "Generalized multiple sclerosis", "description": "" }, { "id": "DOID:2377", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2377", "name": "insular sclerosis", "description": "" }, { "id": "MONDO:0012956", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012956", "name": "multiple sclerosis, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012956", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012956", "name": "MS2", "description": "" }, { "id": "MONDO:0012956", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012956", "name": "multiple sclerosis, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012957", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012957", "name": "multiple sclerosis, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012957", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012957", "name": "MS3", "description": "" }, { "id": "MONDO:0012957", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012957", "name": "multiple sclerosis, susceptibility to, 3", "description": "" }, { "id": "MONDO:0012958", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012958", "name": "multiple sclerosis, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012958", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012958", "name": "MS4", "description": "" }, { "id": "MONDO:0012958", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012958", "name": "multiple sclerosis, susceptibility to, 4", "description": "" }, { "id": "MIM:612595", "resource": "MIM", "url": "https://www.omim.org/entry/612595", "name": "Multiple sclerosis 3", "description": "Multiple sclerosis 3" } ], "unlinked_id_list": [], "evidence": [ { "id": "2377", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2377" } ] }, { "disease_id": "DOID:676", "recommended_name": { "id": "DOID:676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:676", "name": "systemic juvenile rheumatoid arthritis", "description": "A rheumatoid arthritis that involves an autoimmune disease onset in children under 16 which attacks the healthy cells and tissue of located_in joint." }, "synonyms": [ { "id": "DOID:676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:676", "name": "Pauciarticular onset juvenile chronic arthritis", "description": "" }, { "id": "DOID:676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:676", "name": "acute juvenile rheumatoid arthritis", "description": "" }, { "id": "DOID:676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:676", "name": "juvenile chronic polyarthritis", "description": "" }, { "id": "DOID:676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:676", "name": "juvenile idiopathic arthritis", "description": "" }, { "id": "DOID:676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:676", "name": "monarticular juvenile rheumatoid arthritis", "description": "" }, { "id": "DOID:676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:676", "name": "pauciarticular juvenile arthritis", "description": "" }, { "id": "DOID:676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:676", "name": "Still's disease", "description": "" }, { "id": "DOID:676", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:676", "name": "juvenile rheumatoid arthritis", "description": "" }, { "id": "MONDO:0011429", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011429", "name": "juvenile idiopathic arthritis", "description": "Juvenile idiopathic arthritis (JIA) is the term used to describe a group of inflammatory articular disorders of unknown cause that begin before the age of 16 and last over 6 weeks. The term juvenile idiopathic arthritis was chosen to signify the absence of any known mechanism underlying the disorder and to highlight the necessity of excluding other types of arthritis occurring in well defined diseases (in particular arthritis occurring in association with infectious, inflammatory and haematooncologic diseases)." }, { "id": "MONDO:0011429", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011429", "name": "Arthritis, Juvenile Rheumatoid", "description": "" }, { "id": "MONDO:0011429", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011429", "name": "JIA", "description": "" }, { "id": "MONDO:0011429", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011429", "name": "Juvenile idiopathic arthritis", "description": "" }, { "id": "MONDO:0011429", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011429", "name": "juvenile idiopathic arthritis", "description": "" }, { 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} ], "gene": [ { "name": "sh2d7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRU3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-160728-119", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160728-119", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "101884039", "url": "https://www.ncbi.nlm.nih.gov/gene/101884039", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101884039", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884039", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CNIMPSI", "url": "https://omabrowser.org/oma/group/CNIMPSI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PRU3", "url": "https://www.orthodb.org/?gene=A0A8M9PRU3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14388", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14388", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14388:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14388:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021329812", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329812", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PRU3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PRU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-160728-119", "url": "https://zfin.org/ZDB-GENE-160728-119", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLTMEQIEAAMYQKMKKSDRLNEEKMEGFTMEGGQKEQILQWFVETQAMFILSDGNFPRWFQGFISRQEAEDQLRDRDVGCFLIRLSEKAIGYILSYKGQDRCRHFVINQTKTGLFVVSGDSTTHNSLAELIDHFKITPIQPFGEYLTSYSTEMDTVEEDDGNELYDVVQNSPIVTSGVSVKALTSLWEQATNCPHNMAPVLPSKSNRKLTTSTSIDRNSLSQAMKIPSLPKKNAPLRNSLSAGLPGTNPSHEQHSITESRTSEHYSSQLWPTHHENGQSLTSNSYNPTPSMPQQPPPAPLMTASCSYAVLDPKKMHSGAGRMANMEETELQPNPLYQASTVAYAGLKNQPEVEYDNRANPNDNVLLAENLYQDVPEERDYNTYEHVPESNTYEDIPVKVSNMYASLDEIQTQTPNTLGKKNHKWWKLRLENKK", "length": 434, "header": "tr|A0A8M9PRU3-1|A0A8M9PRU3_DANRE Isoform 1 of Uncharacterized protein sh2d7 OS=Danio rerio OX=7955 GN=sh2d7 PE=4 SV=1 CANONICAL=A0A8M9PRU3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PRU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRU3/entry#A0A8M9PRU3-1", "sequence": { "sequence": "MLTMEQIEAAMYQKMKKSDRLNEEKMEGFTMEGGQKEQILQWFVETQAMFILSDGNFPRWFQGFISRQEAEDQLRDRDVGCFLIRLSEKAIGYILSYKGQDRCRHFVINQTKTGLFVVSGDSTTHNSLAELIDHFKITPIQPFGEYLTSYSTEMDTVEEDDGNELYDVVQNSPIVTSGVSVKALTSLWEQATNCPHNMAPVLPSKSNRKLTTSTSIDRNSLSQAMKIPSLPKKNAPLRNSLSAGLPGTNPSHEQHSITESRTSEHYSSQLWPTHHENGQSLTSNSYNPTPSMPQQPPPAPLMTASCSYAVLDPKKMHSGAGRMANMEETELQPNPLYQASTVAYAGLKNQPEVEYDNRANPNDNVLLAENLYQDVPEERDYNTYEHVPESNTYEDIPVKVSNMYASLDEIQTQTPNTLGKKNHKWWKLRLENKK", "length": 434, "header": "tr|A0A8M9PRU3-1|A0A8M9PRU3_DANRE Isoform 1 of Uncharacterized protein sh2d7 OS=Danio rerio OX=7955 GN=sh2d7 PE=4 SV=1 CANONICAL=A0A8M9PRU3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 289, "start_aa": "Thr", "end_pos": 289, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr289", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101884039", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884039", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZSU9-1", "protein_name": "SH2 domain containing 7", "gene_name": "Sh2d7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGGPEQFHQGKALEEAGNGQALAEIQELALKWFMETQAPSILQNGALPPWFHGFITRKQTEQLLRDKALGSFLIRLSDRAAGYILSYRGSDRCRHFVINQLRNRRYLVSGDTLSHSTLDELLRHYQEVQLEPFGETLAAACPRLEENDLYDAINTGLQQTNLGLEIPAMELPSMLPDKVTSPCLPAKPQVSFLHTKKALDASSRTGSNEESTEVPTRVPPIPQKSPSLLDDSSAGPSGIVYSELKKMNRAQLGPGTEVWGRHRPAPAGNLASSPGREPSRKLSDEDQNKPNSPEPAPSGEKPDQGSTMPYTSLGFPLPPNSEAQGSRATTWRQGFLKLSHEAQSSSEASSADTYQLAETSGLRQEGRDKPDQRGSTYEQIPSCWHSAAKLPCPGVSPTYSQLSGPMDYGYEKIPGTPQLPEPGNTYEQIPAAKNKDTGRVHKPDKFRRLFFTDKKHKS", "length": 459 }, "evidence": [ { "id": "HGNC:34549", "url": "https://alliancegenome.org/gene/HGNC:34549#orthology", "database": "AGR" }, { "id": "RGD:1309791", "url": "https://alliancegenome.org/gene/RGD:1309791#orthology", "database": "AGR" }, { "id": "MGI:2441692", "url": "https://alliancegenome.org/gene/MGI:2441692#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-160728-119", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160728-119#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6NKC9-1", "protein_name": "SH2 domain-containing protein 7", "gene_name": "SH2D7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDSLKQLSLGRDPEGAGDSQALAELQELALKWFMETQAPFILQNGALPPWFHGFITRKQTEQLLRDKALGSFLIRLSDRATGYILSYRGSDRCRHFVINQLRNRRYIISGDTQSHSTLAELVHHYQEAQLEPFKEMLTAACPRPEDNDLYDAITRGLHQTIVDPENPPATAFLTVVPDKAASPRSSPKPQVSFLHAQKSLDVSPRNLSQEESMEAPIRVSPLPEKSSSLLEESFGGPSDIIYADLRRMNQARLGLGTEGSGRHGPVPAGSQAYSPGREAQRRLSDGEQNRPDGLGPVLSGVSPDQGPTESPTSWGCSDAMGSLGATWRQEFPKLSQEAQPCSQGSSADIYEFIGTEGLLQEARDTPDQEGSTYEQIPACWGGPARAPHPGASPTYSPWVHGYKRISGTPELSEPGNTYEQIPATKSKETGRTHKPDKLRRLFFTYRKHKF", "length": 451 }, "evidence": [ { "id": "HGNC:34549", "url": "https://alliancegenome.org/gene/HGNC:34549#orthology", "database": "AGR" }, { "id": "RGD:1309791", "url": "https://alliancegenome.org/gene/RGD:1309791#orthology", "database": "AGR" }, { "id": "MGI:2441692", "url": "https://alliancegenome.org/gene/MGI:2441692#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-160728-119", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160728-119#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5I0Q2-1", "protein_name": "SH2 domain containing 2A", "gene_name": "Sh2d2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEFCLAQTCPQGNHEATSPTFSTFQPMNLTQGRCQDLGCGGKPSMQALREQEVQLSPRVTHTVASASAPGAAWVLESVNREEEEPGKGELSLQAETRAWVQKTQAHWLLLRTAPLWFHGFITRREAERLLQSQPLGCYLVRFSESAVTFVLSYRSRTCCRHFLLAQLGDGRHVVLGEDSAHSQLQDLLQHYTECPLSPYGEMLTQPLARQTAEPAGLSLRGESDSGSRRQDPDTQHSLFIQQGQAHAQAPGHKEKVRASQQKKTSQASRPRPPIPAKPQLPLEVYTSPAPRPHQALPINPVYQEPDEPIAFYAMGRGSPGDAPSNIYAEVDGPREMLPIGHPTLHKCWSRPISGGQGKGVQGKKSSRRPAGRGSPS", "length": 376 }, "evidence": [ { "id": "HGNC:10821", "url": "https://alliancegenome.org/gene/HGNC:10821#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BI17-1", "protein_name": "SH2 domain-containing protein 7", "gene_name": "Sh2d7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGGPEQLHLGKALEEAGGGRALAEIQELALKWFMETQAPSILQNGVLPPWFHGFITRKQTEQLLRDKALGSFLIRLSDRAVGYILSYRGSDRCRHFVINQLRNRRYLVSGDTLSHSTLDELLRHYQEVQLEPFGETLAAACPRLEENDLYDAINTGLQHTNLSLKIPATEFPSMLPDKATSPRLPAKPQVSFLHKKALDMSSRSVSDEVSAEVPTRVPPIPRRSPSLLDESPAGPSDVIYTDLRKINRAQLGLGTEVWGTLRPASAGSLACSPGREPSGKLSDEDQNKPNSLGPAPSGMKPDQGSTMPYTSLGFSLPPSSETLGSQATTWRQGFLKLSHEAQSSSEASSTDTYHLVETPGLQQEARDRPDQRGSPYEQIPTCWHGTAKLSYPGVSPTYSQQSGPMDYGYEKISGTSKLPEPGNTYEQIPAAKNKDTGRVHKPDKFRRLFFTDKKHKF", "length": 458 }, "evidence": [ { "id": "HGNC:34549", "url": "https://alliancegenome.org/gene/HGNC:34549#orthology", "database": "AGR" }, { "id": "RGD:1309791", "url": "https://alliancegenome.org/gene/RGD:1309791#orthology", "database": "AGR" }, { "id": "MGI:2441692", "url": "https://alliancegenome.org/gene/MGI:2441692#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-160728-119", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160728-119#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NP31-1", "protein_name": "SH2 domain-containing protein 2A", "gene_name": "SH2D2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEFPLAQICPQGSHEAPIPTFSTFQITDMTRRSCQNLGYTAASPQAPEAASNTGNAERAEEVPGEGSLFLQAETRAWFQKTQAHWLLQHGAAPAWFHGFITRREAERLLEPKPQGCYLVRFSESAVTFVLTYRSRTCCRHFLLAQLRDGRHVVLGEDSAHARLQDLLLHYTAHPLSPYGETLTEPLARQTPEPAGLSLRTEESNFGSKSQDPNPQYSPIIKQGQAPVPMQKEGAGEKEPSQLLRPKPPIPAKPQLPPEVYTIPVPRHRPAPRPKPSNPIYNEPDEPIAFYAMGRGSPGEAPSNIYVEVEDEGLPATLGHPVLRKSWSRPVPGGQNTGGSQLHSENSVIGQGPPLPHQPPPAWRHTLPHNLSRQVLQDRGQAWLPLGPPQ", "length": 389 }, "evidence": [ { "id": "HGNC:10821", "url": "https://alliancegenome.org/gene/HGNC:10821#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-160728-119", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160728-119#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QXK9-1", "protein_name": "SH2 domain-containing protein 2A", "gene_name": "Sh2d2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEFCLAQPCPQGNHEATSSTFNTFQPMNLTQGRCQNLSCGSRPSMQVMKEQGVQLSPRTNHTVVSASAPGTAWVLGNADRAEEVPGKGDLSLQAETRAWVQKTQAHWLLLKTAPLWFHGFITRREAERLLQPQPLGCYLVRFSESAVTFVLSYRSQTCCRHFLLAQLGDGRHVVLGEDSAHAQLQDLLEHYTECPLSPYGEILTQPLARQTAEPAGLSLRADSDSGSKRQDPDTQLSLLLQQGQAQASGHTEKVWASQQKATSQASRPRPPIPAKPQLPPEVYTSPASRLHQAPPINPIYQEPDEPIAFYAMGRGSPGDAPSNIYAEVEGPSGTAPIGHPILRKCWSRPISRGQVREVQGKISSRSRAERGSPS", "length": 374 }, "evidence": [ { "id": "HGNC:10821", "url": "https://alliancegenome.org/gene/HGNC:10821#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PRU3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PRU3" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 136, "start_aa": "Trp", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 289 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PS19-1", "uniprot_ac": "A0A8M9PS19", "uniprot_id": "A0A8M9PS19_DANRE", "mass": { "chemical_mass": 94285.0, "monoisotopic_mass": 94285.0 }, "refseq": { "ac": "XP_021323880", "name": "uncharacterized protein zgc:162972", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323880" }, "gene_names": [ { "name": "zgc:162972", "type": "synonym", "evidence": [ { "id": "XP_021323880", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323880" }, { "id": "A0A8M9PS19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19" } ] } ], "protein_names": [ { "name": "Uncharacterized protein zgc:162972", "type": "synonym", "evidence": [ { "id": "A0A8M9PS19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein zgc:162972", "type": "synonym", "evidence": [ { "id": "XP_021323880", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323880" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 1% of CDS bases ##RefSeq-Attributes-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323880", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323880" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070424-49", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-49", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PS19", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PS19", "database": "AlphaFoldDB", "categories": [] }, { "id": "558355", "url": "https://www.ncbi.nlm.nih.gov/gene/558355", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558355", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558355", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PS19", "url": "https://www.orthodb.org/?gene=A0A8M9PS19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF151", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF151", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323880", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323880", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PS19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PS19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070424-49", "url": "https://zfin.org/ZDB-GENE-070424-49", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRIHTGEKPYSCPECGKSFRVKKCLENHIKIHTGEKPYMCQECGKSFTEKQNLERHMRIHTGEKPFACPECGRSFRVKQDLKIHVRIHTGEKPFSCQQCGKSFSENKKLESHMRIHTGEKPFVCSHCGKNFRGKQNLESHIRLHTGNKPYTCPQCGKSYNQQKSLEIHIRTHTGEKPFPCHQCGKSFTQQSTLKGHIRIHTGEKPFTCSQCGKSFIEKTKLERHKKIHSGEKPYICQHCKKSFTLKQSLDIHMRIHTGEKLYTCQQCGKSFTEKHKLERHMKIHTGEKPYRCQQCGKCFREKQCLDVHTRIHTGQNPFTCSQCGKSFRLKQKLISHMTVHTEVKPALGIEIVLFTLDQMDIKEEDCVSQSGTHITEQSSLKIKTGETAFTCKQCGEIFTTNQSLESHKVIHTGEQHYFCSECGKSFTQMRYLKNHMKIHAGDHPFTCPECDKCFTMKHSLESHLKIHTGEKPFTCPDCGKKFRLKQSLEGHMRIHTGEKPYTCQNCGKSFREKQILDTHLTIHTGEKPYSCPECGKSFRVKKCLENHIKTHTGEKPYTCQECGKSFAIKQNLERHMRIHTGEKPYSCPECGRSFRVKQDLKIHVRIHTGEKPFSCQQCGKSFTENKKLESHMRIHTGEKPFVCSHCGKNFRGKQNLESHMRLHTGSKPYTCPQCGKSYNQQKSLDIHIRTHTGEKPFACDQCGKSFTHQSNLKGHIRIHTGEKPFTCPQCGKSFIEKTKLERHKKIHSGEKPYDCQHCKKSFTLKQSLDIHMKLHTREKPYSCQQCGKSFRVKQKLVSHMTVHTEEKPALGVEVVLE", "length": 817, "header": "tr|A0A8M9PS19-1|A0A8M9PS19_DANRE Isoform 1 of Uncharacterized protein zgc:162972 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=A0A8M9PS19-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PS19-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19/entry#A0A8M9PS19-1", "sequence": { "sequence": "MRIHTGEKPYSCPECGKSFRVKKCLENHIKIHTGEKPYMCQECGKSFTEKQNLERHMRIHTGEKPFACPECGRSFRVKQDLKIHVRIHTGEKPFSCQQCGKSFSENKKLESHMRIHTGEKPFVCSHCGKNFRGKQNLESHIRLHTGNKPYTCPQCGKSYNQQKSLEIHIRTHTGEKPFPCHQCGKSFTQQSTLKGHIRIHTGEKPFTCSQCGKSFIEKTKLERHKKIHSGEKPYICQHCKKSFTLKQSLDIHMRIHTGEKLYTCQQCGKSFTEKHKLERHMKIHTGEKPYRCQQCGKCFREKQCLDVHTRIHTGQNPFTCSQCGKSFRLKQKLISHMTVHTEVKPALGIEIVLFTLDQMDIKEEDCVSQSGTHITEQSSLKIKTGETAFTCKQCGEIFTTNQSLESHKVIHTGEQHYFCSECGKSFTQMRYLKNHMKIHAGDHPFTCPECDKCFTMKHSLESHLKIHTGEKPFTCPDCGKKFRLKQSLEGHMRIHTGEKPYTCQNCGKSFREKQILDTHLTIHTGEKPYSCPECGKSFRVKKCLENHIKTHTGEKPYTCQECGKSFAIKQNLERHMRIHTGEKPYSCPECGRSFRVKQDLKIHVRIHTGEKPFSCQQCGKSFTENKKLESHMRIHTGEKPFVCSHCGKNFRGKQNLESHMRLHTGSKPYTCPQCGKSYNQQKSLDIHIRTHTGEKPFACDQCGKSFTHQSNLKGHIRIHTGEKPFTCPQCGKSFIEKTKLERHKKIHSGEKPYDCQHCKKSFTLKQSLDIHMKLHTREKPYSCQQCGKSFRVKQKLVSHMTVHTEEKPALGVEVVLE", "length": 817, "header": "tr|A0A8M9PS19-1|A0A8M9PS19_DANRE Isoform 1 of Uncharacterized protein zgc:162972 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=A0A8M9PS19-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:558355", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558355", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZD8-1", "protein_name": "Zinc finger protein 729", "gene_name": "Zfp729", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EMLSFRDVAIDFSAEEWECLDLAQWKLYRDVMLENYNNLVFLGLASCKPYLVTFLEQIQEPSDVKGRATTTMHPGGKCCTCKVCGRVFEWTKVFQNHQIIDLGVKGYECEECTKYTHIPSLLPEEKTIHTVEKPYKCEVCGKAFCIPLLLSKHKIIHTEENPYKCDLCGKAFQHPSRLSRHKKIHSGDKPYKCEVCGKAFHFPSLLLVHKRIHTGEKPYKCEVCGKAFHYPSILSKHKRIHTGEKPYKCEVCGKAFHISSFLSKHKIIHRGEKPYKCDVCGKAFHYPSRLSNHKKIHSGEKPYKCEVCGKAFRILSLLSKHKIIHTEENPYKCEVCGKAFDYPSRLSTHSKMHTEEKPYKCEACGKAFRSLSSLSKHRRIHTGDNYYNSEVCGKAFIYPLRLSKHKKICTGEKPYKCEVCGKAFNDSLVLSKHRAIHTGEKLYKCDVCGKAFYYPSRLNNHRKIHSGEKPYQCEECGKAFCFPSSLSKHKRIHTGEKPYKCKECDKAFRSLSSLSKHRRIHTGEKPYKCEVCGKAFHYPSLLSKHKITHTEEKPYKCEVCGQGFHVPSKLSHHKIIHTGESPYKCEVCGKAFCIPLLLSKHKISHTGENHSNSQLSKKAFIYPSRLSKHKKIHKRVKPYKCEVCGKAFRFPSLLLIHKGIHTGEKPYKCEECGKAFYYPSLLSKHKRVHTGEKPYQCEVCGKGFHVSSSLSKHRIIHTGEKPYKCEVCEKAFRFSSSLSKHKRIHTGKKPYKCEECGKAFHFPSLLSKHKISHTGEKPYNCDLCGKAFYYPSLLSKHKMIHTGEKPHKCDICGKAFHYPSKLSNHKKIHTGEKPYKCEVCGNVFCFASSLSKHKRIHTGENPYKCDVCGKAFYYPSLLCHHKIIHTGEKPYKCEVCGKAFHYPSLLSKHKIIHTGKKPYKCEVCGKAFHYPSRLSKHKKIHGAGEMAQELRELATLSRS", "length": 959 }, "evidence": [ { "id": "SGD:S000003592", "url": "https://alliancegenome.org/gene/SGD:S000003592#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36508-1", "protein_name": "Zinc finger protein 76", "gene_name": "ZNF76", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESLGLHTVTLSDGTTAYVQQAVKGEKLLEGQVIQLEDGTTAYIHQVTVQKEALSFEDGQPVQLEDGSMAYIHRTPREGYDPSTLEAVQLEDGSTAYIHHPVAVPSESTILAVQTEVGLEDLAAEDDEGFSADAVVALEQYASKVLHDSQIPRNGKGQQVGDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHTGEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFQCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKPYTCSTCGKTYRQTSTLAMHKRSAHGELEATEESEQALYEQQQLEAASAAEESPPPKRPRIAYLSEVKEERDDIPAQVAMVTEEDGAPQVALITQDGAQQVSLSPEDLQALGSAISMVTQHGSTTLTIPSPDADLATSGTHTVTMVSADGTQTQPVTIITSGAVVAEDSSVASLRHQQVALLATANGTHIAVQLEEQQTLEEAINVATAAMQQGAVTLETTVSESGC", "length": 570 }, "evidence": [ { "id": "SGD:S000003592", "url": "https://alliancegenome.org/gene/SGD:S000003592#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47043-1", "protein_name": "Zinc-responsive transcriptional regulator ZAP1", "gene_name": "ZAP1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDALTPRDSPKRDDSMATSAATAASAKPDALTIGKEGIVHGHIHNYNNLTYIHGHLHHSAPVNDSSASATPAAAAVADAATSAFASGASHDMGGDCHVNEKCKEYTDCQHFEFLNYHNNPSLTKYNDTATYNSNNHSFANNFHSVASDPTSPQQNSKSDLPRRKDSWFNDDLILLPSSKKNKPNPPPGSDDCYCTPKILEICCDETHPKSEANIKQGESDQPTKKDISENGNDVAIFTDVKNDHLMPNFNLHDQYCNSTNHDSHNHNNTVPDSFSQLMSHLSEIDCDLTCDTPCTASTSATSGHKFVQDHQSSNNDDVFHKYCKFCEESTDNQPCSKHMHLESKPPQLPPKCSSLRKPTNTLQGTNHAYHEHILNTDMDLKILEDLCNISSLYEVPFGKHINHHDHNNAGNGCDGSSTGNNENGNQTMNLLLSSINRCNPKNNLNGSNNNTAGATSTDHQHHHHRIQFHSHKPNRNNIVNNSGISAANTTADLTNNDLNDLISREYSYERFRNQSEPPSLPKVTHQNQKNRRSWPTKDLESTDFSSLEDSLPSSISPPIQTTSTINFNWCFKEEKNNDLKCKWKECPESCSSLFDLQRHLLKDHVSQDFKHPMEPLACNWEDCDFLGDDTCSIVNHINCQHGINFDIQFANPDSFLPGSISKEKHHLLHCPNPQTHEVSKADGAPDMTSANDVSNIPPIKQPEQVICQWDGCNKSFSSAQELNDHLEAVHLTRGKSEYQCLWHDCHRTFPQRQKLIRHLKVHSKYKPYKCKTCKRCFSSEETLVQHTRTHSGEKPYKCHICNKKFAISSSLKIHIRTHTGEKPLQCKICGKRFNESSNLSKHIKTHQKKYKCSDCSKSFDDLGKLNSQKVKCALERKPYL", "length": 880 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-070424-49", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-49#orthology", "database": "AGR" }, { "id": "SGD:S000003592", "url": "https://alliancegenome.org/gene/SGD:S000003592#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q07243-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "Mtf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGEHSPDDNIIFFKGEEDDLTPHDKMLRFVDDNGLVPSSSGTVYDRTTVLIEQDPGTLEDDEDDGQCGEPLPFLVEGEEGFLIDQEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESQGCSKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGHDNKGTAYSALPQHNGSEDTNHSLYLSELGLLSTDSELQENSSSTQDQDLSTISPAIIFESMFQNSDDPGIQDDPLQTAALIDSFNGDAESVIDVPPPAGNSASLSLPLVLQSGISEPPQPLLPATAPSAPPPAPSLGPGSQPAAFGSPPALLQPPEVPVPHSTQFAANHQEFLPHPQAPPQTIVPGLSVVAGAPASAATVASAVAAPAPPQSTTEPLPAMVQTLPLGANSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEQVYFATAVPVASGTGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKERAAGRRKGCSSPPPPEPNPQPPDGPSLQLPP", "length": 675 }, "evidence": [ { "id": "SGD:S000003592", "url": "https://alliancegenome.org/gene/SGD:S000003592#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14872-1", "protein_name": "Metal regulatory transcription factor 1", "gene_name": "MTF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGEHSPDNNIIYFEAEEDELTPDDKMLRFVDKNGLVPSSSGTVYDRTTVLIEQDPGTLEDEDDDGQCGEHLPFLVGGEEGFHLIDHEAMSQGYVQHIISPDQIHLTINPGSTPMPRNIEGATLTLQSECPETKRKEVKRYQCTFEGCPRTYSTAGNLRTHQKTHRGEYTFVCNQEGCGKAFLTSYSLRIHVRVHTKEKPFECDVQGCEKAFNTLYRLKAHQRLHTGKTFNCESEGCSKYFTTLSDLRKHIRTHTGEKPFRCDHDGCGKAFAASHHLKTHVRTHTGERPFFCPSNGCEKTFSTQYSLKSHMKGHDNKGHSYNALPQHNGSEDTNHSLCLSDLSLLSTDSELRENSSTTQGQDLSTISPAIIFESMFQNSDDTAIQEDPQQTASLTESFNGDAESVSDVPPSTGNSASLSLPLVLQPGLSEPPQPLLPASAPSAPPPAPSLGPGSQQAAFGNPPALLQPPEVPVPHSTQFAANHQEFLPHPQAPQPIVPGLSVVAGASASAAAVASAVAAPAPPQSTTEPLPAMVQTLPLGANSVLTNNPTITITPTPNTAILQSSLVMGEQNLQWILNGATSSPQNQEQIQQASKVEKVFFTTAVPVASSPGSSVQQIGLSVPVIIIKQEEACQCQCACRDSAKERASSRRKGCSSPPPPEPSPQAPDGPSLQLPAQTFSSAPVPGSSSSTLPSSCEQSRQAETPSDPQTETLSAMDVSEFLSLQSLDTPSNLIPIEALLQGEEEMGLTSSFSK", "length": 753 }, "evidence": [ { "id": "SGD:S000003592", "url": "https://alliancegenome.org/gene/SGD:S000003592#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LYE3-1", "protein_name": "Zinc finger protein 143B", "gene_name": "znf143b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLAQVNRDTQGMEFQSVDGDPQQVTLCLTEAVTVADDNIDGMDTVSLQAVTLVDGSTAYIQHSPKVSLTENKIMEGQVIQLEDGSAAYVQHLPMSKTGGEGLRLEDGQAVQLEDGTTAYIHAPKETYDQGGLQAVQLEDGTTAYIQHMPQSNTILAIQADGTVADLQTEGTIDAETISVLEQYSTKMEATECGTGLIGRGDSDGVHMQIVLQGQDCRSPRIQHVGEKAFRCEHEGCGKLYTTAHHLKVHERSHTGDKPYICDHLGCGKKFATGYGLKSHVRTHTGEKPYRCQELNCLKSFKTSGDLQKHTRTHTGEKPFKCPFEGCGRSFTTSNIRKVHIRTHTGERPYYCAEPNCGRAFASATNYKNHMRIHTGEKPYVCTVPGCDKRFTEYSSLYKHHVVHTPCKPYNCNHCGKTYKQISTLAMHKRTAHNDTEPIEEEQEGYFEPPAEAIDDPGLMYTPSVVDDDSGSEQVSGSEIMGQHHVALISQDGTQQVLSQADMQAMGGTITMVTQEGTTITIPAHEAMLSSGGAHSVTMVSADGTEGQVAIVTPDLAAYQTEEGELIQDQEQHEVSTSPHPVTLLATSNGTHIAVQLSDHPSLEEAIRIASRIQQGETPGMDD", "length": 623 }, "evidence": [ { "id": "SGD:S000003592", "url": "https://alliancegenome.org/gene/SGD:S000003592#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7ZVR6-1", "protein_name": "Myoneurin", "gene_name": "mynn", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPHITHSEFLLEQLKRQRERSFLCDCTVSIGQAQYRAHHNVLAAFSEYFSTQSVDAGREDPTITLDPESVSSAIFEKLLTYIYTGDLNMDREEIESVQKAASYLGMPEVVARCTLSQDNIKNVGSPMRQAEYEDPRSPLSPDDYEPLEPISEVEERELLREDRAGDDLVSMDEAQSSSEQTPQRVGKRGRKPKTRLYEDEFEVETISAQRGRGRGRGRPRGRPRVRPLSSDSTDQSPAHQAMSPNGSSTSRGSGRPRGRPRVRPLSTANEDPRNVEDDPAANKDQEVEKGNEEQKKETGEKDDGKNDTDNPEEVTAFKRGRGRPRIKPVSTEDQTTNSENVTTNAEDGSEPAKTKDSEGTGRKRGRPRSKPVSSEDPESVISVEISGEEAGEETSQDAEKHTEEGTEDSESNPGNSVRISKRKRILSRKLKESQAGDEEEEEEEEMDDEFENDNEDWAGEEEVKPVQDKHRPICNICGNLFSEMSSLRRHMRIHKGLKPYQCTLCTRSFRQGNQLKTHMRIHTGEKPFTCTSCDSRFAQKCQLVYHCRMHHGEEKPYKCEFCGAAFATSSNLKIHIRKHSGEKPYECGECGKRFTQASTLMYHKRRHTGEKPYICDTCGMAFAVSSSLIAHNRKHTGVTPYICLDCGKPCLTAGELRKHMDVHNDIYSLKKHSILKHNVVPELETTQTSKTDPTQCPLNIPIDHQGLIARVRSALVDSQDHEIQMEPPLPILPPETSLTIQQSAEPQMIIQHADGSEPSMIFQHAEASEAPMLIQHGEPGEQVSYVVEQYEIPATAEMEHTQIVIVQTID", "length": 810 }, "evidence": [ { "id": "SGD:S000003592", "url": "https://alliancegenome.org/gene/SGD:S000003592#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q802Y8-1", "protein_name": "Zinc finger and BTB domain-containing protein 16-A", "gene_name": "zbtb16a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDLTKMGMIQLQNPNHPNALLHKANQMRLAGTLCDVVIMVDSQEFHAHRTVLACTSKMFEILFHRNSQHYTLDFLSPKTFQQILEYAYTATLQAKVEDLDDLLYAAEILEIEYLEEQCLKILETIQSSDENDTEVNMNDGGTEDDEERKGRHGRNLVGSKKHSTEESGYVSAAQQALALPGMVDQSPSVSTSFGLSTMSPTKAAVDSLMSIGQSLLQSTMHPGVGAEQPLHGNSHPMMGEIKTEMMQVDESGEHESPKAMESIASSNGERSGEPDKNRDGPGTPTRSSVITSARELHYVRDEGLGDQQAEVSQMGLEAMAGMTEKHLASLYGIPSNHKNEAMLSMPASMASSLHMSPALAMSMDFSAYGGLLPQSFIQREFFSKLGELAAGIKPDGRSLNERCNVCGAELPDNEAIEQHRKLHSGMKTYGCELCGKRFLDSLRLRMHLLSHSAGEKAIVCDQCGAQFQKEDALEAHRQIHTGSDMAIFCLLCGKRFQTQTALQQHMEVHAGVRSYICSECNRTFPSHTALKRHLRSHTAGDHPFECEFCGSCFRDESTLKGHKRIHTGEKPYECNGCGKKFSLKHQLETHYRVHTGEKPFECKLCHQRSRDYSAMIKHLRTHNGASPYQCTICLEYCPSLSAMQKHMKGHKPEDIPPDWRIEKTYLYLCYV", "length": 671 }, "evidence": [ { "id": "SGD:S000003592", "url": "https://alliancegenome.org/gene/SGD:S000003592#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BMU0-1", "protein_name": "Zinc finger protein 76", "gene_name": "Znf76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESLGLQTVRLSDGTTAYVQQAVKGEKLLEGQVIQLEDGTTAYIHQVTIQKESFSFEDGQPVQLEDGSMAYIHHTPKEGCDPSALEAVQLEDGSTAYIHHPVPVPSDSAILAVQTEAGLEDLAAEDEEGFGTDTVVALEQYASKVLHDSPASHNGKGQQVGDRAFRCGYKGCGRLYTTAHHLKVHERAHTGDRPYRCDFPSCGKAFATGYGLKSHVRTHTGEKPYKCPEELCSKAFKTSGDLQKHVRTHTGERPFRCPFEGCGRSFTTSNIRKVHVRTHTGERPYTCPEPHCGRGFTSATNYKNHVRIHTGEKPYVCTVPGCGKRFTEYSSLYKHHVVHTHCKPYTCSSCGKTYRQTSTLAMHKRSAHGELEATEESEQALYEQQQLEAASAAEESPPPKPTHIAYLSEVKEESSAIPTQVAMVTEEDGPPQVALITQDGTQQVSLSPEDLQALGSAISVVTQHGSTTLTIPGHHEELATSGTHTVTMVSADGTQTQPVTIITSGALVTEDSSVASLHHQQVALLATANGTHIAVQLEDQQTLEEAISVATAAMQQGAVTLETTESGC", "length": 568 }, "evidence": [ { "id": "SGD:S000003592", "url": "https://alliancegenome.org/gene/SGD:S000003592#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96MR9-1", "protein_name": "Zinc finger protein 560", "gene_name": "ZNF560", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAYCLTNCYQYSVTFEDTAVDFTQEEWILLDPVQRNLYRDVMLENYENVAKVGFQLFKPSVISWLEEEELRTLQQGVLQDWAIKHQTSVSALQQEFWKIQTSNGIQMDLVTFDSVAVEFTQEEWTLLDPAQRNLYSDVMLENYKNLSSVGYQLFKPSLISWLEEEEELSTLPRVLQEWKMCLKTKGPALWQDNFCLKTLNGIQLARNQNGEELYDCKQCEDVFCKHPCLKTNMSTQNRGNTSECIQYAKDLLSLYNKTSTIRKVSVFSKHGKSFRLILNVQVQRKCTQDKSFEGTDYGKAFIYQSYLEAHRKTQSGEKLNEWKQCGEAFTHSTSHAVNVETHIIKNPYECKECGKDFRYPTHLNNHMQTHIGIKPYKCKHCGKTFTVPSGFLEHVRTHTGEKPYGCKECGKAFGTSAGLIEHIRCHAREKTFKCDHCGKAFISYPSLFGHLRVHNGEKPYEHKEYGKAFGTSSGVIEDRRSNTGQKRFDCDQCGKVFVSFSSLFAHLRTHTGEKPFKCYKCGKPFTSSACLRIHMRTHTEERLYQCKKCGKAFTKCSYLTKHLRTHAGEKPYECMKCGKAFTERSYLTKHLRRHSGEKPYECKKCGKAFTERSDLTKHLRRHTGDKPYEYKDCGKAFVVSSSLVDHLRTHTGYKPYKCNACEKAYSRSCVLTQHLKTHAAEKTSECNACGNSFRNSMCFHDRLKTLTKIKPYKCKDCGKAFTCHSDLTNHVRIHTGEKPYKCKECGKAFRTSSGRIQHLRTHMGEKPFECDQCGKAFASFSARIAHLKTH", "length": 790 }, "evidence": [ { "id": "SGD:S000003592", "url": "https://alliancegenome.org/gene/SGD:S000003592#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96MU6-1", "protein_name": "Zinc finger protein 778", "gene_name": "ZNF778", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAPDLAHGGHVSRDSVCLHEEQTQAAGMVAGWLINCYQDAVTFDDVAVDFTQEEWTLLDPSQRDLYRDVMLENYENLASVEWRLKTKGPALRQDRSWFRASNETQTARSHNGGQLCDRTQCGEAFSEHSGLSTHVRTQNTGDSCVSNHYERDFFIPCQKTLFKIGEQFSVLGQCGKAFSSTPNVVSQQACTRDRSLDYSSCGEVFLNQSYLQARAGSHNGEETWKWKPCGKALTHSMGCATPVEMHAVRNPHVCRECGKAFRYTAYLTGRVQVHPGEKPCELEECGKASPVSSSLTQHVRIHAAEKPCECKECGKAFTGLSGLSKHVQTDPGQKPYECKDCGKACGGFYLLNEHGKTHTREKPFACVVCGKYFRNSSCLNNHVRIHTGIKPYTCSYCGKAFTVRCGLTRHVRTHTGEKPYTCKDCGKAFCTSSGLTEHVRTHTGEKPYECKDCGKSFTVSSSLTEHARIHTGEKPYECKQCGKAFTGRSGLTKHMRTHTGEKPYECKDCGKAYNRVYLLNEHVKTHTEEKPFICTVCRKSFRNSSCLNKHIQIHTGIKPYECKDCGKTFTVSSSLTEHIRTHTGEKPYECKVCGKAFTTSSHLIVHIRTHTGEKPYICKECGKAFASSSHLIEHRRTHTGEKPYICNECGKAFRASSHLHKHGRIHTGQKPYKCKECGKAYNRFYLLKEHLKTYTEEQVFVCKDCGKSFKNSSCLNHHTQIHTDEKPF", "length": 729 }, "evidence": [ { "id": "SGD:S000003592", "url": "https://alliancegenome.org/gene/SGD:S000003592#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19" } ], "pmid": "" }, { "name": "identical protein binding", "id": "GO:0042802", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042802", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS19", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PS19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS19" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 10, "end_pos": 37, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 401, "end_pos": 403 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PS29-1", "uniprot_ac": "A0A8M9PS29", "uniprot_id": "A0A8M9PS29_DANRE", "mass": { "chemical_mass": 18927.0, "monoisotopic_mass": 18927.0 }, "refseq": { "ac": "XP_068079694", "name": "uncharacterized protein C2orf80 homolog isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079694" }, "gene_names": [ { "name": "c9h2orf80", "type": "recommended", "evidence": [ { "id": "A0A8M9PS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS29" } ] }, { "name": "c9h2orf80", "type": "synonym", "evidence": [ { "id": "XP_068079694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079694" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C2orf80 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "A0A8M9PS29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS29/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C2orf80 homolog isoform X2", "type": "synonym", "evidence": [ { "id": "XP_068079694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079694" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068079694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079694" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS29", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS29" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "c9h2orf80", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS29", "locus": {} } ], "crossref": [ { "id": "110439180", "url": "https://www.ncbi.nlm.nih.gov/gene/110439180", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110439180", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110439180", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR36296", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36296", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36296:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36296:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17718", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17718", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_068079694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068079694", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PS29", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PS29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GG47", "url": "https://www.uniprot.org/uniprotkb/A0AC58GG47", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GG47-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GG47-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFKTCNDYRKICLLNSFSGEYIGRRFREDSFDPKGKSTSTMLDDLAHYDLAISVALWRLNKDEGLNTADNDIGSASLGHFSQYPNRLEREAMILSSFAGMLLNNLPLEDILFLYNCKPSASYPHNDAKGNIVHPFSLSYHPFAMLSSFKAVDCSKKTHPSSETLDQGTG", "length": 169, "header": "tr|A0A8M9PS29-1|A0A8M9PS29_DANRE Isoform 1 of Uncharacterized protein C2orf80 homolog isoform X2 OS=Danio rerio OX=7955 GN=c9h2orf80 PE=4 SV=1 CANONICAL=A0A8M9PS29-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PS29-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS29/entry#A0A8M9PS29-1", "sequence": { "sequence": "MFKTCNDYRKICLLNSFSGEYIGRRFREDSFDPKGKSTSTMLDDLAHYDLAISVALWRLNKDEGLNTADNDIGSASLGHFSQYPNRLEREAMILSSFAGMLLNNLPLEDILFLYNCKPSASYPHNDAKGNIVHPFSLSYHPFAMLSSFKAVDCSKKTHPSSETLDQGTG", "length": 169, "header": "tr|A0A8M9PS29-1|A0A8M9PS29_DANRE Isoform 1 of Uncharacterized protein C2orf80 homolog isoform X2 OS=Danio rerio OX=7955 GN=c9h2orf80 PE=4 SV=1 CANONICAL=A0A8M9PS29-1" }, "locus": {} }, { "isoform_ac": "A0AC58GG47-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS29/entry#A0AC58GG47-1", "sequence": { "sequence": "MEAKRVKRDVKTLLGEYIGRRFREDSFDPKGKSTSTMLDDLAHYDLAISVALWRLNKDEGLNTADNDIGSASLGHFSQYPNRLEREAMILSSFAGMLLNNLPLEDILFLYNCKPSASYPHNDAKGNIVHPFSLSYHPFAMLSSFKAVDCSKKTHPSSETLDQGTG", "length": 165, "header": "tr|A0AC58GG47-1|A0AC58GG47_DANRE Computationally mapped isoform of Uncharacterized protein C2orf80 homolog isoform X1 OS=Danio rerio OX=7955 GN=c9h2orf80 PE=4 SV=1 CANONICAL=A0A8M9PS29-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110439180", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110439180", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PS36-1", "uniprot_ac": "A0A8M9PS36", "uniprot_id": "A0A8M9PS36_DANRE", "mass": { "chemical_mass": 36493.0, "monoisotopic_mass": 36493.0 }, "refseq": { 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:: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068072676", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072676" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS36", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS36" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100007966", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS36", "locus": {} } ], "crossref": [ { "id": "100007966", "url": "https://www.ncbi.nlm.nih.gov/gene/100007966", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": 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"eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 61, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PS39-1", "uniprot_ac": "A0A8M9PS39", "uniprot_id": "A0A8M9PS39_DANRE", "mass": { "chemical_mass": 72656.0, "monoisotopic_mass": 72656.0 }, "refseq": { "ac": "XP_021325136", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325136" }, "gene_names": [ { "name": "LOC101884430", "type": "recommended", "evidence": [ { "id": "A0A8M9PS39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS39" } ] }, { "name": "LOC101884430", "type": "synonym", "evidence": [ { "id": "XP_021325136", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325136" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8M9PS39", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS39/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_021325136", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325136" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325136", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325136" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS39", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS39" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101884430", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS39", "locus": {} } ], "crossref": [ { "id": "A0A8M9PS39", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PS39", "database": "AlphaFoldDB", "categories": [] }, { "id": "101884430", "url": "https://www.ncbi.nlm.nih.gov/gene/101884430", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": 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[ "Protein Classification" ] }, { "id": "PTHR45842:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45842:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325136", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325136", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PS39", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS39", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PS39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS39-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWFRFALLQLLPQLTLSSWCPSECVCDIRGSAKCIGNINDIPQLDPTKTFLLLLNDTNIKVLKDRSFQQLSLLLRVMITHSTLDTIQPEAFHGAPQLRSIKMSSNALAVVPPKVFIEQRNLEQLQLDGNQIVSVSSELFEGLVSMTELDLSKNRISQLDAGVFQSLTKLIYLNLAGNQLRNLPKTVFHNLGNLQTLVLTSNHLEILESGSFDHLSNLLVLMLQKNQIREIPPRLFWHMPSLLTLSMSNNQLQHIPPESFYYLPNLTKLTLYKNPLIFLPDQLIGHMPRLQELYLYETNLVTVPSNLFANTTNLQYLNVHLNSNLTLLPKDVFCCLPNLRKLSLKHNNLRELHPEIFSNLNRLQILTLDGNKFESLPSTIFLNTSRLEILNLNQNHLRFLPGDVFVHAGALKVLTLSDNRWMCDCSILGFAEWIRDNWRMISDLDNGVACYEPNYLQNHLLQTLTYKDLQCGLSVLQTTLMTNINTFTVPILMSTIPRLISTTSREATETTSPFPVVTSQVSPTSNYIFIKEGIDYYNDYDNDPAFYKTIVLDNGPEIVHNNYYNGWVYLWTLPLTGPYSGFMLALYLVLLVTGAVLIMVSLYALYRLHKVMWVLGTHTMGDRIMARRVRRFRINP", "length": 635, "header": "tr|A0A8M9PS39-1|A0A8M9PS39_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC101884430 PE=4 SV=1 CANONICAL=A0A8M9PS39-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PS39-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS39/entry#A0A8M9PS39-1", "sequence": { "sequence": "MWFRFALLQLLPQLTLSSWCPSECVCDIRGSAKCIGNINDIPQLDPTKTFLLLLNDTNIKVLKDRSFQQLSLLLRVMITHSTLDTIQPEAFHGAPQLRSIKMSSNALAVVPPKVFIEQRNLEQLQLDGNQIVSVSSELFEGLVSMTELDLSKNRISQLDAGVFQSLTKLIYLNLAGNQLRNLPKTVFHNLGNLQTLVLTSNHLEILESGSFDHLSNLLVLMLQKNQIREIPPRLFWHMPSLLTLSMSNNQLQHIPPESFYYLPNLTKLTLYKNPLIFLPDQLIGHMPRLQELYLYETNLVTVPSNLFANTTNLQYLNVHLNSNLTLLPKDVFCCLPNLRKLSLKHNNLRELHPEIFSNLNRLQILTLDGNKFESLPSTIFLNTSRLEILNLNQNHLRFLPGDVFVHAGALKVLTLSDNRWMCDCSILGFAEWIRDNWRMISDLDNGVACYEPNYLQNHLLQTLTYKDLQCGLSVLQTTLMTNINTFTVPILMSTIPRLISTTSREATETTSPFPVVTSQVSPTSNYIFIKEGIDYYNDYDNDPAFYKTIVLDNGPEIVHNNYYNGWVYLWTLPLTGPYSGFMLALYLVLLVTGAVLIMVSLYALYRLHKVMWVLGTHTMGDRIMARRVRRFRINP", "length": 635, "header": "tr|A0A8M9PS39-1|A0A8M9PS39_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC101884430 PE=4 SV=1 CANONICAL=A0A8M9PS39-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101884430", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101884430", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS39", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS39" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of synapse assembly", "id": "GO:0051965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051965", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS39", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS39" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS39", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS39" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 309, "end_pos": 311, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 382, "end_pos": 384, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 264, "end_pos": 266 }, { "start_pos": 309, "end_pos": 311 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 382, "end_pos": 384 }, { "start_pos": 55, "end_pos": 57 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PS61-1", "uniprot_ac": "A0A8M9PS61", "uniprot_id": "A0A8M9PS61_DANRE", "mass": { "chemical_mass": 19520.0, "monoisotopic_mass": 19520.0 }, "refseq": { "ac": "XP_021323920", "name": "LIM domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323920" }, "gene_names": [ { "name": "limd1b", "type": "recommended", "evidence": [ { "id": "A0A8M9PS61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS61" } ] }, { "name": "limd1b", "type": "synonym", "evidence": [ { "id": "XP_021323920", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323920" } ] } ], "protein_names": [ { "name": "LIM domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_021323920", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323920" }, { "id": "A0A8M9PS61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS61/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323920" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS61", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS61" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "limd1b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS61", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060810-174", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-174", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PS61", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PS61", "database": "AlphaFoldDB", "categories": [] }, { "id": "798800", "url": "https://www.ncbi.nlm.nih.gov/gene/798800", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047172", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047172", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:798800", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798800", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PS61", "url": "https://www.orthodb.org/?gene=A0A8M9PS61", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24219", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24219", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24219:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24219:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323920", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323920", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PS61", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS61", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PS61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS61-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060810-174", "url": "https://zfin.org/ZDB-GENE-060810-174", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDTHTLSLGWCVKCSGGVYSSDQACQAMGRVYHDRCFTCCTCGQKLKGKPFYDFSGQVFCEEDYLYSSVKHFAEVCSSCGYLITDMVLQALGKSFHRECFRCVVCNETLEGQQFSVDAQNKIYCVKDYHRFLAQTCAVCEQLILPIEGSNESMRVLTMGRSYHVACYEGKSNI", "length": 173, "header": "tr|A0A8M9PS61-1|A0A8M9PS61_DANRE Isoform 1 of LIM domain-containing protein 1 OS=Danio rerio OX=7955 GN=limd1b PE=4 SV=1 CANONICAL=A0A8M9PS61-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PS61-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS61/entry#A0A8M9PS61-1", "sequence": { "sequence": "MDTHTLSLGWCVKCSGGVYSSDQACQAMGRVYHDRCFTCCTCGQKLKGKPFYDFSGQVFCEEDYLYSSVKHFAEVCSSCGYLITDMVLQALGKSFHRECFRCVVCNETLEGQQFSVDAQNKIYCVKDYHRFLAQTCAVCEQLILPIEGSNESMRVLTMGRSYHVACYEGKSNI", "length": 173, "header": "tr|A0A8M9PS61-1|A0A8M9PS61_DANRE Isoform 1 of LIM domain-containing protein 1 OS=Danio rerio OX=7955 GN=limd1b PE=4 SV=1 CANONICAL=A0A8M9PS61-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:798800", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798800", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B5DEH0-1", "protein_name": "LIM domain-containing protein 1", "gene_name": "Limd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGASNNPEFEETRRVFATKMAKIHLQQQQQQQLLQEEALPRAGRSPINGGNRQGVSSKLAADGAAKPPLAVPTVAPGLATTTMAVQSSYPPQEQRTRPSAHGARPGSQNCGSREGPVSSQRPALHGLGPCEDPSCLTHGDYYDNFSLASPQWGDKPEESPSMSLSVGSGWPGCPGNDSLSHRSCGDSHPYHPQLSMCSGRSFESGQDSGIGGHSSEKPTGLWSTASSQRVNLGFSSTGLENGTPAQPKGTTVSAPMVPSSTSQGACLRRDSSLGYEAPGRVFKPLVDTQPWLQDGPKSYLSVSAPLSSTTSKDNAQTGMTAGLDPKLGCVESGTSPKPSPTSNVHPVMSAPSELSCKESPPSWSTDSSLGPVLPESPTPSRVRLPCQTLTPGPELGPSTAELKLEALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGDLYHDACFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHRCYPLEDHLFCHSCHVKRLEKGPSPASLHQHHF", "length": 663 }, "evidence": [ { "id": "HGNC:6612", "url": "https://alliancegenome.org/gene/HGNC:6612#orthology", "database": "AGR" }, { "id": "MGI:1352502", "url": "https://alliancegenome.org/gene/MGI:1352502#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9QXD8-1", "protein_name": "LIM domain-containing protein 1", "gene_name": "Limd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNNPEFEETRRVFATKMAKIHLQQQQQQQLLQEEALPRAGRSPVNGGNRQGASGKLAADGAAKPPLAVPTVAPGLATTTAAAQPSYPSQEQRIRPSAHGARPGSQNCGSREGPVSSQRPALHGLSPSCEDPSCLTHGDYYDNFSLASPQWGDKPEGCPSVSLGVGSGWPGCPGNDSTLPKSCGDHHPYQPQLSTVCSGRSFESGISGQDGGIGGHSSEKPTGLWSTASSQRVNLGFSSMGLENGTSAQPKGTTVSAPMVPSSASQGACPKRDSGLGYEASGRVFKPLVDTQPWLQDGPKSYLSVSAPLSSTAGKDSTQPGMTTGLDPKFGCVESGTSPKPSPTSNVHPVMSTPSELSCKESSPSWSTDSSLEPVLPGSPTPSRVRLPCQTLAPGPELGPSTAELKLEALTQRLEREMDAHPKADYFGSCVKCSKGVFGAGQACQAMGDLYHDACFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHRCYPLEDHLFCHSCHVKRLEKGPSPAPLHQHHF", "length": 668 }, "evidence": [ { "id": "HGNC:6612", "url": "https://alliancegenome.org/gene/HGNC:6612#orthology", "database": "AGR" }, { "id": "MGI:1352502", "url": "https://alliancegenome.org/gene/MGI:1352502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060810-174", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-174#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UGP4-1", "protein_name": "LIM domain-containing protein 1", "gene_name": "LIMD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNNPEFEETRRVFATKMAKIHLQQQQQQLLQEETLPRGSRGPVNGGGRLGPQARWEVVGSKLTVDGAAKPPLAASTGAPGAVTTLAAGQPPYPPQEQRSRPYLHGTRHGSQDCGSRESLATSEMSAFHQPGPCEDPSCLTHGDYYDNLSLASPKWGDKPGVSPSIGLSVGSGWPSSPGSDPPLPKPCGDHPLNHRQLSLSSSRSSEGSLGGQNSGIGGRSSEKPTGLWSTASSQRVSPGLPSPNLENGAPAVGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMSKPNVDPQPWFQDGPKSYLSSSAPSSSPAGLDGSQQGAVPGLGPKPGCTDLGTGPKLSPTSLVHPVMSTLPELSCKEGPLGWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPELRPSAAELKLEALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLYSGFQQSADRCFLCGHLIMDMILQALGKSYHPGCFRCVICNECLDGVPFTVDSENKIYCVRDYHKVLAPKCAACGLPILPPEGSDETIRVVSMDRDYHVECYHCEDCGLELNDEDGHRCYPLEDHLFCHSCHVKRLEKRPSSTALHQHHF", "length": 676 }, "evidence": [ { "id": "HGNC:6612", "url": "https://alliancegenome.org/gene/HGNC:6612#orthology", "database": "AGR" }, { "id": "MGI:1352502", "url": "https://alliancegenome.org/gene/MGI:1352502#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060810-174", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-174#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VY77-1", "protein_name": "LIM domain-containing protein jub", "gene_name": "jub", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTTQRTQTQARNPGNSDSDYETLMQRLHIGGGGGAGVGGGGGSGGPGDGGVAMRSYQRSPGAIENYLQESQQQQQQHQMQQMQQLHHNQDYKLYERGNIIAASKYATPRPVEQIQHTHNGSAQIYAPTAQILGQRIAPQKHSPVYENLEFYGQFDSNHKRAQPQSPGSRQSAILNGYLLMQPIRAGRFAHTPVPENQGSASLGTTRAAGGPPPPSGRSAALGPTGDLEEHAAPIYENIIPHSGQRAQPQASPATATMYQEMQPTSNSSGSSSTAGLDLNALLASPMHQRSISSNTASSSSLGSPTQRYRNLSLPSHLSPVPTAQSVAKLQQHTPVKSPGGAINVSVNPNYIEDINSSDYVCMTANLHRNTAAGLATGRAAATGAPAQRTVQEPPIITSSLAMGMATAAPPTTSNAPTSAAAAPAAPTSTASLRATPIAMTAPLAVATSPTPSQGSTAVNAALKPRRGLTKNLLPYSVTPPRPAGPTEAQRKIEELTRQLEEEIEQSEEHGEYFGICHTCGEKVKGAGQACQAMGNLYHTNCFICCSCGRALRGKAFYNVHGRVYCEEDYMYSGFQQTAEKCAICGHLIMEMILQAMGKSYHPGCFRCCVCNECLDGVPFTVDVDHKIYCVNDYHRMFAPKCASCGKGITPVEGTDETVRVVSMDKDFHVDCYICEECGMQLTDEPDKRCYPLDGRLLCRGCHLQRLALQSSPHARHQEPVCASYQYMG", "length": 728 }, "evidence": [ { "id": "HGNC:6612", "url": "https://alliancegenome.org/gene/HGNC:6612#orthology", "database": "AGR" }, { "id": "MGI:1352502", "url": "https://alliancegenome.org/gene/MGI:1352502#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PS61", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS61" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PS61", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PS61" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 9, "end_pos": 70, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 106, "end_pos": 108 }, { "start_pos": 150, "end_pos": 152 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PSA0-1", "uniprot_ac": "A0A8M9PSA0", "uniprot_id": "A0A8M9PSA0_DANRE", "mass": { "chemical_mass": 22286.0, "monoisotopic_mass": 22286.0 }, "refseq": { "ac": "XP_021323960", "name": "uncharacterized protein il11b", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323960" }, "gene_names": [ { "name": "il11b", "type": "recommended", "evidence": [ { "id": "A0A8M9PSA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA0" } ] }, { "name": "il11b", "type": "synonym", "evidence": [ { "id": "XP_021323960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323960" } ] } ], "protein_names": [ { "name": "Uncharacterized protein il11b", "type": "synonym", "evidence": [ { "id": "A0A8M9PSA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein il11b", "type": "synonym", "evidence": [ { "id": "XP_021323960", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323960" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_021323960.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323960" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PSA0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "il11b", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-051019-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051019-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PSA0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PSA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "108180095", "url": "https://www.ncbi.nlm.nih.gov/gene/108180095", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020438", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020438", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:108180095", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108180095", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PSA0", "url": "https://www.orthodb.org/?gene=A0A8M9PSA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16922", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16922", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16922:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16922:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323960", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323960", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PSA0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PSA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-051019-2", "url": "https://zfin.org/ZDB-GENE-051019-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKLSPDSTFPLIILMACVELFDFIRARPANLPQGKKHLSTLYQDMRMLLKLTSQQMNANELTDFEHSLSSLPSLNYSVKDLHSLEVSSTLAQLYSGLKSFKFHLDWVQRNSDELGNDYSKTKKIVHLIQAIIQKVLQELGQTAPEIVHPTLPPLETFWQLYQTNAEIHKKLLIFCDYYTRALGSLKRKHPDTPS", "length": 194, "header": "tr|A0A8M9PSA0-1|A0A8M9PSA0_DANRE Isoform 1 of Uncharacterized protein il11b OS=Danio rerio OX=7955 GN=il11b PE=4 SV=2 CANONICAL=A0A8M9PSA0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PSA0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA0/entry#A0A8M9PSA0-1", "sequence": { "sequence": "MKLSPDSTFPLIILMACVELFDFIRARPANLPQGKKHLSTLYQDMRMLLKLTSQQMNANELTDFEHSLSSLPSLNYSVKDLHSLEVSSTLAQLYSGLKSFKFHLDWVQRNSDELGNDYSKTKKIVHLIQAIIQKVLQELGQTAPEIVHPTLPPLETFWQLYQTNAEIHKKLLIFCDYYTRALGSLKRKHPDTPS", "length": 194, "header": "tr|A0A8M9PSA0-1|A0A8M9PSA0_DANRE Isoform 1 of Uncharacterized protein il11b OS=Danio rerio OX=7955 GN=il11b PE=4 SV=2 CANONICAL=A0A8M9PSA0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108180095", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108180095", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7TFR3-1", "protein_name": "Interleukin-11", "gene_name": "il11a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKLLGDSSSSLLLSLLLAQLHLLASAFPVHHRRNQIDFDKLSNQTKLLLTLTRNLLKDRVFSTEINHHRFKSLPAISSRASDFATLEVKPTLSQLHANLKSFQHHFEWLNNITHKQQHSIPKLTDMVSHIGGLVNSLQRQMNHIGAPRLPVPSPSLPPIPAFHWEMVQTSQELLEQFSLFCDWAARVLGRTRSLLTSREAPVVGSTGTSPSGPIRIVGK", "length": 219 }, "evidence": [ { "id": "RGD:621475", "url": "https://alliancegenome.org/gene/RGD:621475#orthology", "database": "AGR" }, { "id": "HGNC:5966", "url": "https://alliancegenome.org/gene/HGNC:5966#orthology", "database": "AGR" }, { "id": "MGI:107613", "url": "https://alliancegenome.org/gene/MGI:107613#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P20809-1", "protein_name": "Interleukin-11", "gene_name": "IL11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNCVCRLVLVVLSLWPDTAVAPGPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQLRDKFPADGDHNLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSLKTLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWGGIRAAHAILGGLHLTLDWAVRGLLLLKTRL", "length": 199 }, "evidence": [ { "id": "RGD:621475", "url": "https://alliancegenome.org/gene/RGD:621475#orthology", "database": "AGR" }, { "id": "HGNC:5966", "url": "https://alliancegenome.org/gene/HGNC:5966#orthology", "database": "AGR" }, { "id": "MGI:107613", "url": "https://alliancegenome.org/gene/MGI:107613#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051019-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051019-2#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P47873-1", "protein_name": "Interleukin-11", "gene_name": "Il11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNCVCRLVLVVLSLWPDRVVAPGPPAGSPRVSSDPRADLDSAVLLTRSLLADTRQLAAQMRDKFPADGDHSLDSLPTLAMSAGTLGSLQLPGVLTRLRVDLMSYLRHVQWLRRAGGPSLKTLEPELGALQARLERLLRRLQLLMSRLALPQAAPDQPVIPLGPPASAWGSIRAAHAILGGLHLTLDWAVRGLLLLKTRL", "length": 199 }, "evidence": [ { "id": "RGD:621475", "url": "https://alliancegenome.org/gene/RGD:621475#orthology", "database": "AGR" }, { "id": "HGNC:5966", "url": "https://alliancegenome.org/gene/HGNC:5966#orthology", "database": "AGR" }, { "id": "MGI:107613", "url": "https://alliancegenome.org/gene/MGI:107613#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051019-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051019-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q99MF5-1", "protein_name": "Interleukin-11", "gene_name": "Il11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNCVCRLVLVVLSLWPDRVVAPGPPAGSPRVSSDPRADLDSAVLLTRSLLADTRQLAAQMRDKFPADGDHNLDSLPTLAMSAGTLGSLQLPGVLTRLRVDLMSYFRHVQWLRRAAGPSLKTLEPELGALQARLERLLRRLQLLMSRLALPQAAPDQPAVPLGPPASAWGSIRAAHAILGGLHLTLDWAVRGLLLLKTRL", "length": 199 }, "evidence": [ { "id": "RGD:621475", "url": "https://alliancegenome.org/gene/RGD:621475#orthology", "database": "AGR" }, { "id": "HGNC:5966", "url": "https://alliancegenome.org/gene/HGNC:5966#orthology", "database": "AGR" }, { "id": "MGI:107613", "url": "https://alliancegenome.org/gene/MGI:107613#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-051019-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-051019-2#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PSA0", "url": 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activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PSA0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", 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"uniprot_ac": "A0A8M9PSA4", "uniprot_id": "A0A8M9PSA4_DANRE", "mass": { "chemical_mass": 24562.0, "monoisotopic_mass": 24562.0 }, "refseq": { "ac": "XP_021325206", "name": "uncharacterized protein si:rp71-36a1.5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325206" }, "gene_names": [ { "name": "si:rp71-36a1.5", "type": "recommended", "evidence": [ { "id": "A0A8M9PSA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA4" } ] }, { "name": "si:rp71-36a1.5", "type": "synonym", "evidence": [ { "id": "XP_021325206", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325206" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:rp71-36a1.5", "type": "synonym", "evidence": [ { "id": "A0A8M9PSA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:rp71-36a1.5", "type": "synonym", "evidence": [ { "id": "XP_021325206", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325206" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325206", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325206" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PSA4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:rp71-36a1.5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA4", "locus": {} } ], "crossref": [ { "id": "A0A8M9PSA4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PSA4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100001329", "url": "https://www.ncbi.nlm.nih.gov/gene/100001329", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100001329", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001329", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9PSA4", "url": "https://www.orthodb.org/?gene=A0A8M9PSA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_021325206", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325206", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PSA4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PSA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MNIRKTEAEDYKLNIFSSSSRPRQNVFKVSVNDDSAAKVKRKFVKGGESVTLDTRIQIKTTDVIKWHFNDHLIAEINENGEERFREGLMLDNQTGSLTIMNTTDSGDYYVEIMISRSNNFNVTILKNFSVNVTAVSGLSSLFKAILPYFTLPAAAAAVIAATTVGVIYHRRVSSKKNEKKNLKEILYAAPKKVVLLMEKGPNPADGRGSGFNGPISQNKQQ", "length": 221, "header": "tr|A0A8M9PSA4-1|A0A8M9PSA4_DANRE Isoform 1 of Uncharacterized protein si:rp71-36a1.5 OS=Danio rerio OX=7955 GN=si:rp71-36a1.5 PE=4 SV=1 CANONICAL=A0A8M9PSA4-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PSA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA4/entry#A0A8M9PSA4-1", "sequence": { "sequence": "MNIRKTEAEDYKLNIFSSSSRPRQNVFKVSVNDDSAAKVKRKFVKGGESVTLDTRIQIKTTDVIKWHFNDHLIAEINENGEERFREGLMLDNQTGSLTIMNTTDSGDYYVEIMISRSNNFNVTILKNFSVNVTAVSGLSSLFKAILPYFTLPAAAAAVIAATTVGVIYHRRVSSKKNEKKNLKEILYAAPKKVVLLMEKGPNPADGRGSGFNGPISQNKQQ", "length": 221, "header": "tr|A0A8M9PSA4-1|A0A8M9PSA4_DANRE Isoform 1 of Uncharacterized protein si:rp71-36a1.5 OS=Danio rerio OX=7955 GN=si:rp71-36a1.5 PE=4 SV=1 CANONICAL=A0A8M9PSA4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100001329", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001329", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 121, "end_pos": 123 }, { "start_pos": 127, "end_pos": 129 }, { "start_pos": 131, "end_pos": 133 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PSA9-1", "uniprot_ac": "A0A8M9PSA9", "uniprot_id": "A0A8M9PSA9_DANRE", "mass": { "chemical_mass": 66722.0, "monoisotopic_mass": 66722.0 }, "refseq": { "ac": "XP_073793228", "name": "uncharacterized protein si:ch211-274k16.2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073793228" }, "gene_names": [ { "name": "si:ch211-274k16.2", "type": "recommended", "evidence": [ { "id": "A0A8M9PSA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA9" } ] }, { "name": "si:ch211-274k16.2", "type": "synonym", "evidence": [ { "id": "XP_073793228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073793228" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch211-274k16.2 isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8M9PSA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch211-274k16.2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_073793228", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073793228" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073793228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073793228" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PSA9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-274k16.2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110411-199", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-199", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PSA9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PSA9", "database": "AlphaFoldDB", "categories": [] }, { "id": "100002907", "url": "https://www.ncbi.nlm.nih.gov/gene/100002907", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PSA9", "url": "https://www.orthodb.org/?gene=A0A8M9PSA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_073793228", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073793228", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PSA9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PSA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IG59", "url": "https://www.uniprot.org/uniprotkb/A0AC58IG59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IG59-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IG59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IG65", "url": "https://www.uniprot.org/uniprotkb/A0AC58IG65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IG65-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IG65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110411-199", "url": "https://zfin.org/ZDB-GENE-110411-199", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPYKGTVRLMKMLTRLVLFCLCCCHLADAVKSVSVTEGDSVTLNSDLTELPTGRLIMWKFEPNGNLLAKIDLTSKLISIFDKGEFRGRLKVDNQTASLTITDSKKTDAGVYIMSISHNIKRTFLFNVTVYARLPVPVIISESPPNSSSSSSSVQYCSVLCSVVNVSAASLSWYKGNRLLSSISVSDLNNSFPLHMECLDGSYSCVVSNPISNQTQHVNNTEHCQPCSGASGEIVESVSVTVGDSLTLHTKVNQMELGSVLEWRFEKKMIALINSDPNKITHVITNTSDRLELNRQSGNLKIMNVKMADSGLYELDIISPSGSTSNIFNVIVINKASDGVRVESVRERDSVILPTGLNQIRRDDRLTWKFEGTIIAQINQTGIFPHDVLDGRFKNRLHLNPWTGSLTITNVKSNTSGEYVLDISKSSSGFTTHKTFSVTTIDGDNMVSTTEGTTVILASGVFEIHQDDVIIWRSEHGDSVIAKISNGTFSTFDGADGRFRDTLKLDHQTGSLTIRNIKTEHAGLYHMDMIGSRRTVFKRISLSVCPRDWSVCLIAVVAVAFLLLVLAGVILVRGKMGCCCSDHGEKRTEDGMKIMELKGKGRKMNRI", "length": 606, "header": "tr|A0A8M9PSA9-1|A0A8M9PSA9_DANRE Isoform 1 of Uncharacterized protein si:ch211-274k16.2 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-274k16.2 PE=4 SV=2 CANONICAL=A0A8M9PSA9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PSA9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA9/entry#A0A8M9PSA9-1", "sequence": { "sequence": "MPYKGTVRLMKMLTRLVLFCLCCCHLADAVKSVSVTEGDSVTLNSDLTELPTGRLIMWKFEPNGNLLAKIDLTSKLISIFDKGEFRGRLKVDNQTASLTITDSKKTDAGVYIMSISHNIKRTFLFNVTVYARLPVPVIISESPPNSSSSSSSVQYCSVLCSVVNVSAASLSWYKGNRLLSSISVSDLNNSFPLHMECLDGSYSCVVSNPISNQTQHVNNTEHCQPCSGASGEIVESVSVTVGDSLTLHTKVNQMELGSVLEWRFEKKMIALINSDPNKITHVITNTSDRLELNRQSGNLKIMNVKMADSGLYELDIISPSGSTSNIFNVIVINKASDGVRVESVRERDSVILPTGLNQIRRDDRLTWKFEGTIIAQINQTGIFPHDVLDGRFKNRLHLNPWTGSLTITNVKSNTSGEYVLDISKSSSGFTTHKTFSVTTIDGDNMVSTTEGTTVILASGVFEIHQDDVIIWRSEHGDSVIAKISNGTFSTFDGADGRFRDTLKLDHQTGSLTIRNIKTEHAGLYHMDMIGSRRTVFKRISLSVCPRDWSVCLIAVVAVAFLLLVLAGVILVRGKMGCCCSDHGEKRTEDGMKIMELKGKGRKMNRI", "length": 606, "header": "tr|A0A8M9PSA9-1|A0A8M9PSA9_DANRE Isoform 1 of Uncharacterized protein si:ch211-274k16.2 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-274k16.2 PE=4 SV=2 CANONICAL=A0A8M9PSA9-1" }, "locus": {} }, { "isoform_ac": "A0AC58IG59-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA9/entry#A0AC58IG59-1", "sequence": { "sequence": "MKRLVLMMFSLIFLNGASGEIVESVSVTVGDSLTLHTKVNQMELGSVLEWRFEKKMIALINSDPNKITHVITNTSDRLELNRQSGNLKIMNVKMADSGLYELDIISPSGSTSNIFNVIVINKASDGVRVESVRERDSVILPTGLNQIRRDDRLTWKFEGTIIAQINQTGIFPHDVLDGRFKNRLHLNPWTGSLTITNVKSNTSGEYVLDISKSSSGFTTHKTFSVTTIDGDNMVSTTEGTTVILASGVFEIHQDDVIIWRSEHGDSVIAKISNGTFSTFDGADGRFRDTLKLDHQTGSLTIRNIKTEHAGLYHMDMIGSRRTVFKRISLSVCPRDWSVCLIAVVAVAFLLLVLAGVILVRGKMGCCCSDHGEKRTEDGMKIMELKGKGRKMNRI", "length": 394, "header": "tr|A0AC58IG59-1|A0AC58IG59_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-274k16.2 isoform X2 OS=Danio rerio OX=7955 GN=si:ch211-274k16.2 PE=4 SV=1 CANONICAL=A0A8M9PSA9-1" }, "locus": {} }, { "isoform_ac": "A0AC58IG65-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA9/entry#A0AC58IG65-1", "sequence": { "sequence": "MPYKGASGEIVESVSVTVGDSLTLHTKVNQMELGSVLEWRFEKKMIALINSDPNKITHVITNTSDRLELNRQSGNLKIMNVKMADSGLYELDIISPSGSTSNIFNVIVINKASDGVRVESVRERDSVILPTGLNQIRRDDRLTWKFEGTIIAQINQTGIFPHDVLDGRFKNRLHLNPWTGSLTITNVKSNTSGEYVLDISKSSSGFTTHKTFSVTTIDGDNMVSTTEGTTVILASGVFEIHQDDVIIWRSEHGDSVIAKISNGTFSTFDGADGRFRDTLKLDHQTGSLTIRNIKTEHAGLYHMDMIGSRRTVFKRISLSVCPRDWSVCLIAVVAVAFLLLVLAGVILVRGKMGCCCSDHGEKRTEDGMKIMELKGKGRKMNRI", "length": 383, "header": "tr|A0AC58IG65-1|A0AC58IG65_DANRE Computationally mapped isoform of Mast/stem cell growth factor receptor kita isoform X3 OS=Danio rerio OX=7955 GN=si:ch211-274k16.2 PE=4 SV=1 CANONICAL=A0A8M9PSA9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 413, "end_pos": 415, "annotation": "n_glycosylation_sequon" }, { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 93, "end_pos": 95, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PSA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSA9" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 218, "start_aa": "Pro", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 145, "end_pos": 147 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 188, "end_pos": 190 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 218, "end_pos": 220 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 378, "end_pos": 380 }, { "start_pos": 413, "end_pos": 415 }, { "start_pos": 485, "end_pos": 487 }, { "start_pos": 93, "end_pos": 95 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8M9PSB3-1", "uniprot_ac": "A0A8M9PSB3", "uniprot_id": "A0A8M9PSB3_DANRE", "mass": { "chemical_mass": 31807.0, "monoisotopic_mass": 31807.0 }, "refseq": { "ac": "XP_021325216", "name": "SLAM family member 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325216" }, "gene_names": [ { "name": "LOC100538170", "type": "recommended", "evidence": [ { "id": "A0A8M9PSB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSB3" } ] }, { "name": "LOC100538170", "type": "synonym", "evidence": [ { "id": "XP_021325216", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325216" } ] } ], "protein_names": [ { "name": "SLAM family member 5", "type": "synonym", "evidence": [ { "id": "XP_021325216", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325216" }, { "id": "A0A8M9PSB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSB3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_021325216.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325216", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325216" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PSB3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSB3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100538170", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSB3", "locus": {} } ], "crossref": [ { "id": "A0A8M9PSB3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PSB3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100538170", "url": "https://www.ncbi.nlm.nih.gov/gene/100538170", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100538170", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100538170", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR21063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325216", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325216", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PSB3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PSB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSB3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MFLLLGLCWWHLTGVFSEKLSVMEGDSVRLQTKMTKLHEDDNILWTYSKSLIAKISMEKQIFSTFDGPDDRFRGRLKMDKQTGSLTITNIRLEHAGEYGVKITGEKLTKISFGVSVYARLSSPSITRECSSSSQNNCSVVCSVVNVSAVSLSWYKGSSVLSSIIVSDLSISLSLPLEVEYQDRNTYSCVINNTISNQTTHLDINTLCQPCPDEDLHLFNIVWICAAVGSLLILVSAVMCCISKKCRKTVHNCEEDQSDSTLCKEKSRKKKSDMQAVYCNVPKRR", "length": 284, "header": "tr|A0A8M9PSB3-1|A0A8M9PSB3_DANRE Isoform 1 of SLAM family member 5 OS=Danio rerio OX=7955 GN=LOC100538170 PE=4 SV=2 CANONICAL=A0A8M9PSB3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PSB3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSB3/entry#A0A8M9PSB3-1", "sequence": { "sequence": "MFLLLGLCWWHLTGVFSEKLSVMEGDSVRLQTKMTKLHEDDNILWTYSKSLIAKISMEKQIFSTFDGPDDRFRGRLKMDKQTGSLTITNIRLEHAGEYGVKITGEKLTKISFGVSVYARLSSPSITRECSSSSQNNCSVVCSVVNVSAVSLSWYKGSSVLSSIIVSDLSISLSLPLEVEYQDRNTYSCVINNTISNQTTHLDINTLCQPCPDEDLHLFNIVWICAAVGSLLILVSAVMCCISKKCRKTVHNCEEDQSDSTLCKEKSRKKKSDMQAVYCNVPKRR", "length": 284, "header": "tr|A0A8M9PSB3-1|A0A8M9PSB3_DANRE Isoform 1 of SLAM family member 5 OS=Danio rerio OX=7955 GN=LOC100538170 PE=4 SV=2 CANONICAL=A0A8M9PSB3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100538170", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100538170", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], 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"name": "Muckle-Wells syndrome", "description": "An intermediate form of cryopyrin-associated periodic syndrome (CAPS) and is characterized by recurrent fever (with malaise and chills), recurrent urticaria-like skin rash, sensorineural deafness, general signs of inflammation (eye redness, headaches, arthralgia/myalgia) and potentially life-threatening secondary amyloidosis (AA type)." }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle-Wells syndrome", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "neutrophilic urticaria", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "MWS", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "Muckle Wells syndrome", "description": "" }, { "id": "MONDO:0008633", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008633", "name": "urticaria, deafness and amyloidosis", "description": "" }, { "id": "MIM:191900", "resource": "MIM", "url": "https://www.omim.org/entry/191900", "name": "Muckle-Wells syndrome", "description": "Muckle-Wells syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050854", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050854" } ] }, { "disease_id": "DOID:0080208", "recommended_name": { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated steatotic liver disease", "description": "A steatotic liver disease characterized by at least one of five specified cardiometabolic risk factors and no other discernible cause with normal to no alcohol use. The five cardiometabolic risk factors are: (1) higher than normal body mass index or waist circumference; (2) higher than normal serum glucose or glycated hemoglobin level, or type 2 diabetes; (3) higher than normal blood pressure or hypertensive treatment; (4) higher than normal plasma triglycerides or lipid lowering treatment; and (5) lower than normal plasma high-density lipoprotein cholesterol." }, "synonyms": [ { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "nonalcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "non-alcoholic fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "NAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-associated fatty liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic dysfunction-related steatotic liver disease", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MAFLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "MASLD", "description": "" }, { "id": "DOID:0080208", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080208", "name": "metabolic-associated fatty liver disease", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "NAFLD2", "description": "" }, { "id": "MONDO:0013246", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013246", "name": "fatty liver disease, nonalcoholic, susceptibility to, 2", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "NAFLD1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "fatty liver disease, nonalcoholic, susceptibility to, 1", "description": "" }, { "id": "MONDO:0021105", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021105", "name": "liver disease, alcoholic, susceptibility to, 1", "description": "" }, { "id": "MIM:613282", "resource": "MIM", "url": "https://www.omim.org/entry/613282", "name": "Non-alcoholic fatty liver disease 1", "description": "Non-alcoholic fatty liver disease 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080208", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080208" } ] }, { "disease_id": "DOID:0080270", "recommended_name": { "id": "DOID:0080270", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080270", "name": "autosomal dominant nonsyndromic deafness 34", "description": "An autosomal dominant nonsyndromic deafness that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q44." }, "synonyms": [ { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "hearing loss, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "DFNA34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "autosomal dominant nonsyndromic deafness 34", "description": "" }, { "id": "MONDO:0033261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033261", "name": "deafness, autosomal dominant 34, with or without inflammation", "description": "" }, { "id": "MIM:617772", "resource": "MIM", "url": "https://www.omim.org/entry/617772", "name": "Deafness, autosomal dominant, 34, with or without inflammation", "description": "Deafness, autosomal dominant, 34, with or without inflammation" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080270", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080270" } ] }, { "disease_id": "DOID:0090029", "recommended_name": { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "CINCA Syndrome", "description": "An autoimmune disease characterized by neonatal onset of cutaneous symptoms, chronic meningitis, and joint manifestations with recurrent fever and inflammation that has_material_basis_in heterozygous mutation in the NLRP3 gene on chromosome 1q." }, "synonyms": [ { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "IOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "NOMID syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic infantile neurological cutaneous articular syndrome", "description": "" }, { "id": "DOID:0090029", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090029", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "Chronic Infantile Neurological, Cutaneous, and Articular (CINCA) syndrome is characterized by skin rash, joint involvement, chronic meningitis with granulocytes and, in some cases, sensorineural hearing loss and ocular signs." }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA/NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "NOMID syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Neonatal-Onset Multisystem Inflammatory Disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur-Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic infantile neurological cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "chronic neurologic cutaneous and articular syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "cryopyrin-associated periodic syndrome 3", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal-onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "CINCA", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "IOMID", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "Prieur Griscelli syndrome", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "infantile onset multisystem inflammatory disease", "description": "" }, { "id": "MONDO:0011776", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011776", "name": "neonatal onset multisystem inflammatory disease", "description": "" }, { "id": "MIM:607115", "resource": "MIM", "url": "https://www.omim.org/entry/607115", "name": "Chronic infantile neurologic cutaneous and articular syndrome", "description": "Chronic infantile neurologic cutaneous and articular syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090029", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090029" } ] }, { "disease_id": "DOID:0090062", "recommended_name": { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "familial cold autoinflammatory syndrome 1", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP gene on chromosome 1q44." }, "synonyms": [ { "id": "DOID:0090062", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090062", "name": "FCAS1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "Any familial cold autoinflammatory syndrome in which the cause of the disease is a mutation in the NLRP3 gene." }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "NLRP3 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP3", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold autoinflammatory syndrome type 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "familial cold inflammatory syndrome 1", "description": "" }, { "id": "MONDO:0007349", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007349", "name": "FCAS1", "description": "" }, { "id": "MIM:120100", "resource": "MIM", "url": "https://www.omim.org/entry/120100", "name": "Familial cold autoinflammatory syndrome 1", "description": "Familial cold autoinflammatory syndrome 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090062", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090062" } ] }, { "disease_id": "DOID:0090063", "recommended_name": { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "familial cold autoinflammatory syndrome 2", "description": "A familial cold autoinflammatory syndrome characterized by autosomal dominant inheritance that has_material_basis_in heterozygous mutation in the NLRP12 gene on chromosome 19q13." }, "synonyms": [ { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "DOID:0090063", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0090063", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "An autoinflammatory disease caused by mutations in the NLRP12 gene. It is characterized by periodic fevers beginning in the first year of life that are triggered by cold exposure. Episodes occur more than once per month." }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "FCAS2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NALP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NAPS12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12 familial cold autoinflammatory syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "NLRP12-associated hereditary periodic fever syndrome", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome 2", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome caused by mutation in NLRP12", "description": "" }, { "id": "MONDO:0012724", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012724", "name": "familial cold autoinflammatory syndrome type 2", "description": "" }, { "id": "MIM:611762", "resource": "MIM", "url": "https://www.omim.org/entry/611762", "name": "Familial cold autoinflammatory syndrome 2", "description": "Familial cold autoinflammatory syndrome 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0090063", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0090063" } ] }, { "disease_id": "DOID:12351", "recommended_name": { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "alcoholic hepatitis", "description": "" }, "synonyms": [ { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic hepatitis", "description": "" }, { "id": "DOID:12351", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12351", "name": "acute alcoholic liver disease", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12351", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12351" } ] }, { "disease_id": "DOID:1555", "recommended_name": { "id": "DOID:1555", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1555", "name": "urticaria", "description": "A skin disease characterized by skin rash notable for pale red, raised and itchy bumps, located_in the upper dermis." }, "synonyms": [], "unlinked_id_list": [ "DOID:0060220" ], "evidence": [ { "id": "1555", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1555" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:9452", "recommended_name": { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "steatotic liver disease", "description": "A lipid storage disease characterized by the accumulation of large vacuoles of triglyceride fat in at least 5% of hepatocytes." }, "synonyms": [ { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Fatty change of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "Steatosis of liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "alcoholic fatty liver", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic lipidosis", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "SLD", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "fatty liver disease", "description": "" }, { "id": "DOID:9452", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9452", "name": "hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis, congenital", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "fatal neonatal hepatic steatosis", "description": "" }, { "id": "MONDO:0009220", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009220", "name": "visceral steatosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "9452", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9452" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSD3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nlrc7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSD3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9PSD3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8M9PSD3", "database": "AlphaFoldDB", "categories": [] }, { "id": "556007", "url": "https://www.ncbi.nlm.nih.gov/gene/556007", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556007", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556007", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ERRFASH", "url": "https://omabrowser.org/oma/group/ERRFASH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17776", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17776", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325236", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325236", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSD3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PSD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSD3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-478", "url": "https://zfin.org/ZDB-GENE-070912-478", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSEEQGKMSLSEKHSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKPMSAKSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKQTSAKSVISDSCVSGSVFVKSDCSKDGDLPNFSEETPSSGKSFEHKTSDSDFQTHRKHKGFQDGLLGIFQDLENQIMNYLKHELEKFKKILQKENIIDFVKDFNENRCSIKEAALDLTLYFLREMKQEESADTLEDELIFIHQLKCGLQKKYQCVFEGIAQQGDSRLLKNIYTDLYITQGGSEQVNTEHEVRQIEVASRRHEAQELQVECRHLFEASEQDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQEISFIFPLPFREMNLKEKETLSLMELITQFFPETKGLNLTRRNRFKVLFILDGLDECRLPLNFAGNETCCDVSSPASLDVLLTNLIKGNLLPSALIWITSRPAAASKIPPDCIDRLTEIRGFNDAQKEEYFRKRLTDENQAKEIIDHVKQSKSLFIMCHIPVFCWISATVLQNILQEKRNNDVKHNQADDASKTLQESNTEDTPKTLTQMYTHFLRFQIQQSRRKYNGEYTPDVSWDKDAILSLGKLAFHHLLNNNLIFYDTDLEACGIDVYKASVYSGMCTQIFKEETGIILGTMYCFVHLTLQEFIAALYAHLILDTNKKSVFDQDSKKINESMIDLLKTAVDKALESDNGHLDLFLRFLLGLSLQSNRRILRGLLTPQDQDDQSTEKILQYIKQKFDANLSPERSINLFYCLNELNEQTLVKEIQTHLSKGSLSSADFSSAHWSALAFVLLTSDEEMEEFELQKFHKSDECLIRLSAVIKTCKRALLNDCNLTDRSCSALATVLESDTSLKELNMSNNNLQDSGVKLLCTGLKDMKCELEILRLSDCNITEEGYKALASALRSNPSHLLELDLRGNDPGESGVKELDDLLQDPNCTLKTLRFLSPSAEESCQFVNGVVGKNPLLLKTLNLNDFRSTRNHPFIYEIEDTQVNHLAALLQDKHCRVNMLILGGCSFTDDQWESLTSALKLNPSHLRELILMWNGPGESGVKILSDFLIEPQLKLEKLCLCYCSITEERCEILTSALKSNPSHLRELNLSQNIPGDSGMKNLSDLLMNPQSKLEKLQLCKCSITEEQCVILTSALKSNPSHLRDLNLSLNNLGDSGVKTLSDLLMKPHLKMEKLWLCKCSITEEQCVILASALKSNPSHLRELSLSENNLGDSGVKNLSDLLMKPQFKLEKLHLSHCSITEEQCEILTSALKSNPSHLRELDISKNQIRNTGVNLLCDVLNNSDCKLETLRLNDCGITDVSSLTQCLTNTKALQFLKVLYLRENHIGDSKQELSDVVRDSNCELSVDEFSLPDFGQIKDIKCCIS", "length": 1370, "header": "tr|A0A8M9PSD3-1|A0A8M9PSD3_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 12 OS=Danio rerio OX=7955 GN=nlrc7 PE=4 SV=1 CANONICAL=A0A8M9PSD3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PSD3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSD3/entry#A0A8M9PSD3-1", "sequence": { "sequence": "MSEEQGKMSLSEKHSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKPMSAKSVISDSCVSGSVSVKSDCSKDGDLPNFSVEKQTSAKSVISDSCVSGSVFVKSDCSKDGDLPNFSEETPSSGKSFEHKTSDSDFQTHRKHKGFQDGLLGIFQDLENQIMNYLKHELEKFKKILQKENIIDFVKDFNENRCSIKEAALDLTLYFLREMKQEESADTLEDELIFIHQLKCGLQKKYQCVFEGIAQQGDSRLLKNIYTDLYITQGGSEQVNTEHEVRQIEVASRRHEAQELQVECRHLFEASEQDKQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQEISFIFPLPFREMNLKEKETLSLMELITQFFPETKGLNLTRRNRFKVLFILDGLDECRLPLNFAGNETCCDVSSPASLDVLLTNLIKGNLLPSALIWITSRPAAASKIPPDCIDRLTEIRGFNDAQKEEYFRKRLTDENQAKEIIDHVKQSKSLFIMCHIPVFCWISATVLQNILQEKRNNDVKHNQADDASKTLQESNTEDTPKTLTQMYTHFLRFQIQQSRRKYNGEYTPDVSWDKDAILSLGKLAFHHLLNNNLIFYDTDLEACGIDVYKASVYSGMCTQIFKEETGIILGTMYCFVHLTLQEFIAALYAHLILDTNKKSVFDQDSKKINESMIDLLKTAVDKALESDNGHLDLFLRFLLGLSLQSNRRILRGLLTPQDQDDQSTEKILQYIKQKFDANLSPERSINLFYCLNELNEQTLVKEIQTHLSKGSLSSADFSSAHWSALAFVLLTSDEEMEEFELQKFHKSDECLIRLSAVIKTCKRALLNDCNLTDRSCSALATVLESDTSLKELNMSNNNLQDSGVKLLCTGLKDMKCELEILRLSDCNITEEGYKALASALRSNPSHLLELDLRGNDPGESGVKELDDLLQDPNCTLKTLRFLSPSAEESCQFVNGVVGKNPLLLKTLNLNDFRSTRNHPFIYEIEDTQVNHLAALLQDKHCRVNMLILGGCSFTDDQWESLTSALKLNPSHLRELILMWNGPGESGVKILSDFLIEPQLKLEKLCLCYCSITEERCEILTSALKSNPSHLRELNLSQNIPGDSGMKNLSDLLMNPQSKLEKLQLCKCSITEEQCVILTSALKSNPSHLRDLNLSLNNLGDSGVKTLSDLLMKPHLKMEKLWLCKCSITEEQCVILASALKSNPSHLRELSLSENNLGDSGVKNLSDLLMKPQFKLEKLHLSHCSITEEQCEILTSALKSNPSHLRELDISKNQIRNTGVNLLCDVLNNSDCKLETLRLNDCGITDVSSLTQCLTNTKALQFLKVLYLRENHIGDSKQELSDVVRDSNCELSVDEFSLPDFGQIKDIKCCIS", "length": 1370, "header": "tr|A0A8M9PSD3-1|A0A8M9PSD3_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 12 OS=Danio rerio OX=7955 GN=nlrc7 PE=4 SV=1 CANONICAL=A0A8M9PSD3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:556007", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556007", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JW23-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPATAKDALHRLSTYLEELEAGELKKFKLYLGIAEELGQDKIPRGRMEMAGPLEMAQLMVAHMGTKEAWLLALSTFERIHRKDLWERGQGEDLVRVTPSNGLCSLESQSTCLSDVSPDAPRKDPQITYKDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPIWAQQKLLETGWEHSRTRGHQASPIQMETLFEPDEERPEPPRTVVLQGAAGMGKSMLTHKVMLDWADGRLFQDQFDYVFYISCRELNRSHTQCSVHDLLSSCWPEHGAPLEDLIRAPDRLLFIIDGFHELHPSFHDVQGPWCHCWEEKRPTELLLGSLIRRLLLPQLSLLITTRPCALEKLHGLLEHPRHVEILGFSEAEREEYFYRYFHNTGQASQVFSFMRDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTSRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFEEEDLGKHGLDGAEVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFTAMYCALHGREAVRRALAEYGFSERNFLAHTVRFLFGLLNEEMRCYLERNLGWTISPQVKEEALAWIQNKARSEGSTLQHGSLELLSCLYEIQEEDFIQQALSHFQVVVVRNLSTKMEHVVCSFCARYCRGTEVLHLYGSAYSTGAEDGPPEPPGAQTQSTHSQERNILPDIYSAYLSATICTNSNLIELALYRNALGSQGVRLLCQGLRHANCKLQNLRLKRCHISGSACQDLAAAIIANRNLIRLDLSGNSIGVLGLELLCEGLQHPMCRLQMIQLRKCLLEAAAGRALASVLSNNSHLVELDLTGNPLEDLGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLMELDLGLNDLGDSGALLLCEGLRHPDCKLQTLRLGICRLGSDACAGVASVLQVNTCLRELDLSFNDLGDRGLWLLGEGLRHQTCRLQKLWLDSCGLTSKACEDLSSVLGISQTLNELYLTNNALGDTGVRLLCKRLRHPGCKLRVLWLFGMDLNKVTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1PS14-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:dkey-222h21.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDNMLQRIKNQHKTSLKNKYERLFEGIEVKETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPENLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGIDVSDASVYSGICTEILKEESVIQQRKVYSFIHLSFQEFLAAFHVFYHHITCSTEASLDSLHDLQKRIINKSTESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKRSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELKLQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITPGLRKYACVLTLDPNTAHTHLVLSEKNRQARNVTDPQPYPDHPDRFKNNEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYSCDTIYTVWHNNKSADIIAPSACTNRVGVYVDVPSGSLSFYSVTDTHTLTLIHTFNTTFTEELYTGFGIYPEASVSLCQI", "length": 892 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3ANC0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch73-168d20.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSRKRRSSSPESSCVSIKSDASMDNPPTLRLGESPAKHRRSSSLGSSCVSMKSDASMDNPPTLRLGESPAKHRRSSSPESSCVSMKSDASMDNPPTLRLGESPAKHSDNQKRSQSNKGQKQLDAIFKDLEETNIDEMRKVLRRFKMLLSPDYSVRDEEEEEGQRQINEAFLKITLHALQKMNQTDLASKLQTKLISVSQQQLKSRLKQRFERFTEGVSNRGNTKLLNDIYTEVYITEGGAGNIDDEHEVRQIETSSSRFPEIPIRCCDIFKSLLGQDKAIRTVLTKGVAGIGKTASVQKFILDWAEGKANQDVHFIFPLPFRDLNLIKEKRMSLMELLCCFCPELKPIDYNNFKTVFIYDGLDEWRLPLDFRNNEILWDMNKVASVDALLTNLLQGNLLPSAVHWITTRPAAACQIPAEFIDRVTEVRGFKDLQRAEYFWKRIKDQNLANKIITHIQSSRSLHIMCRIPVFCWISATVLEKIFGEANSADIPKTLTQMFIHLLIVQTNLKTQKYDRECDVNLEKARKSILSLAKLAFEQLEKGNLIFYEEDLKQCGIDVREASVCSGVCTQIFREEFGLQLQKVFSFVHLSVQEFLAALFKFLSFAEENNKSSMTQFMKNEVDRALQSPNGHLDLFLRFLLGLSLDSNQTLLQGLFTPLDTSHSRDETIEYIKSKIRENPSPERSINLFYCLNELNDHSLVQEVQTYLTSTRSHRLSGVKLSPALWSALVFVLLNSTKDLDEFELRQYDFTEECLLRLLPVVKASRKADLKGGNLTDQICSALASALSSSSCCLRELDLSENRLQLSGIRLFSAGLKSPNCKLEILKLSNCSIREEGCASLVSALLSNPSHLRELNLNSNQPGYSTVKLLSDLLENPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLNGSNIREKDCAAFISSLLSNPFHLRELSLSWNKPGDSGVKLLSDLLKDSRCKLEKLELECCSIIEEGCAALALALVSNPSHLRELNLNNNEPGDLGVNLLSFLLKNPQCKLEKLELEYCCIGAKSCASLASAFVSNPSHLRELNLNWNTPEYPAVKLLSDYLKDPHCKLEKLQLYNCCIGEEGCAALALALISNPSHLRELNLNNNEPGDSGVKLLSDLLKDPRCKLEKLQLEYCCIGEEGCAALVSGLKSNPSHLRELNLNRNEPGNLGAKMLSDLLKDPLFELEKLELDDCSIENNGFADLVSGLKSNPSNIRELNLNSNKFIFSGLNLLCDLLRDQQCKLRKLQLECCNIDEEGCAALALALISNPSHLRELNLNYNNPGGLGVKLLSVLLKNPHCKLEKLELSHCSISENYLAALNSALSSNPAHLRELNLNYNENTRQ", "length": 1388 }, "evidence": [ { "id": "HGNC:21269", "url": "https://alliancegenome.org/gene/HGNC:21269#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQ59-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLKIFQNLTAESGKGIRDYVVQIRFCFIMDDTQISRDENVSPGCSSVHQKRSDPEPSCVSMRSDWSMDPPISFKSKDTPPDFSSVHQKSTESEPSCVSMRSDDESVDQPLHVRSGDTETDLSHEALNTFRSDLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIIPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLMNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHLLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDGFEEIKKPSLWSKVKDLLYLNSSQLVSLSELHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQIILQRLMILKSRSIQINKTVEYIKMKIRTIDSPEKFINLFHCLNELGDHSLVEEIQQYLKSGRINRAKLSESQWSAVAFVLLTSEKKLEEFHINEFVGETEKIFIFMKLLPVIRECRSVQLNNCGLTDEGCAALASALRSNPEHLRELNLSGNRLGDSVTLLSALLEDPRCNLEILWLSYCGLTDEGCAALASALRLNPEHLRELNLSHNNISKSTVKLLSDLKHNPHNKLETLYI", "length": 837 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:21269", "url": "https://alliancegenome.org/gene/HGNC:21269#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B0M3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "si:dkey-7i4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESDEQHNDTLVQMGSSGNSGINADLRAEKEATVIAPLLNGNNITGPVTFNYCSNSAENEPQKYPKTADKHTEKQDDLKLQKILETHRTYMKKKVDCILDCTKENAEHFKAFYTELFIAEGDMQDVNQEHEILKIDDAFKKKKASLRSIRCKDIFAELKAKSEKNTVLTKGIAGIGKTVSVRKFILDWAEGQTNHDIHCVFLLPFREINLMTNEDFNLHEFLLKFYPELKELETSVLFQQCNLAFIFDGLDESRLPLNFKSRTLNNVEERSSVDMLFTSLVKGNLLPSALVWVTSRPAAANQIPPRYVGLFTEVQGFTDQQKEKYFRNRIADETQASKIISHIKTSRSLYIMCHIPVFCWITATVLQDILQRNIESIGTTLTEMYIHFLLIQMNMKSQKYDPEEEREYAKLLEANREVILKLAKLAFEQLKKENVVFYEQDLKDCGIDVNVEFTGMIAEIFKVEHGLHEAKVFYFVHLSVQEFLAAVYVFFCFLNRNTHELTFFFESSQNTPRELQFLFKKTFRKVKFHDLIKRATDKAMRSKRGHLDLFLRFLLGISLESSQNLLKGLFSHVIDTTRSIKKISPHFKHLQNKNISCDCSVNLFFCLLELKDHSLYEEIQRSLNSDRRPSKELSSSMCTVLTYIVLMSEKELDELNPKRFTSSQENYRKLVPAVRCCRKALFNGCGLDEMSFQTISSALQSSDSYLTELELSNNHLQDSGVKLLSDGLKSSHCQLNILRLCGCGLTDQSCESLSSALQSSNSVLRELDMSNNMLKDSGVKLLAVALKSLNCKLERLRFSMCNLTAESCESLSSVVELSNSVLRELDLSNNDLQDSGVKLLSDGLKRNCRLEILRLSGCMVTEVGCGFLSSALSSTTSTLRELDLSYNHPGDSGEKLLSDAHNQPNCRLCVDHGGEFRLTTGLHKYARFFTLDPNTANARLILSEENRKVTCVRKKQPYPDHPDRFEGYLQVLCRESVCGRSYWEIEWTGVVFISVSYSSIGRMGSDKECWFGFSNQSWSLFCSSDRCSFTHSSTEIDLPVKHTSSRIGVYVDHSAGTLSFYSVSDTVSLIHSVQTTFTQPLHPGFYISLGSSVKLC", "length": 1096 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B2F7-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-13n15.11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEEEKSFSSKSSVFLGREKECGTACKMSFTDEKEEESGIHNLLEKASSPVPSYVSLKSDRSMAEPPKFSDEAKHFPLSHSEKEEQKCAVHYQFQGAASSLPSNVSLKSDRSMAEPPKFSHVAQHLQSSLSEKVEVCAVHHRRLSSTISSYVSLKSDRSMAEPPRFSDASEQFKYGHRVVQDQPECPQPGSSSAGEQLNIFQSVDEISQRIKEHHKTSIKQKYESLCEGFNKQENKTLLNKIYTQLYIIEGEREGVNEEHEVVQIEKAKTERLQGTPINCNDIFQPVHDPCYGRSDEKDKVRTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFLFVLPFRELNLVKDDQYSLHKLLLDFHPELLEINTRIYDLCKVLFVFDGLDESRITLTFSHCEKISDVSTSSSVSMLLSNLIKGELLPSALIWITSRPAAASHIPSHYISRVTEVQGFSDPQKEEYFRKRISNQDQASRIISHIRAARSLHIMCHIPVFCCITATVLQNILEQDLSAEIPKTLTEMYIHFLIIQTDVKRQKFDQNVEGIEKDLKLLLEASRDLILKLAELAFKGLMNGHVLFYDEDLKACGIDVNEACVHSGFCTEFFDEESVIKSRKVYCFVHLSFQEFFAALFVFSSYLNKSSDVLKIFQKKKGRRKVKLQSDEVSLDVFLNGVVDEALKSDNGHLDLFLRFLHGLLLESNQRLLQGLLTHMEDDPESMTKAMKNLKQSQKQNVRPERWINLSHCLIEMKDTSVSEDIQAYLKNEGKRKIYLSSPHCSALANMLLMAEDVLEELDLKKYNTTSMQALRRLIPAVRNCRKAILVGCNLTEQSCETVASALQPANSPVRELDMSNNDLQDSGVKLISVGLKSSHCKLEILRLKCCKLTMQCCETVASALLSANSRLRELDLSYNELQDSGVEWLAAGLKSPHCKLEILSLSGCKLTSQSCEVLASVLQSEGSRLGQLDLNNNDLQDSGLELLSAGLKICKLEKLRLATCNLTSQSCKTMAASLQSVNCVLKELDLSNNDLQDSGVEILSAGLKSPHCKLEILRLSICNLSDRSCATVASVLQSANCLRELNLSKNDLQDSGVKMLSDGLKSSLCVLEILRMSGCFITEDGCSVLASVLNSKPTHLRELDLSCNHPGDLGVQLLTARLNDQTCKLEILNLEHEGKFRIAAGLRRYACDLTLDPDTAHTHLSLSDGNRTVTHVAEEQSYPDHPDRFECCPQVLCAESLRGRCSWEAEWSGKSGVYISASYKGIRRKGQSDDCEFGSNDKSWRLVCSDNSFLAWHNNERTKMRPPSSSSRSKRVGVYLDWPAGTLSFYSISDKNKLTHLHTFSSTFSEPLYAGFGLYSGTSVSLCPIETQKTVAMT", "length": 1368 }, "evidence": [ { "id": "HGNC:21269", "url": "https://alliancegenome.org/gene/HGNC:21269#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YSM0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:ch211-181d7.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSHKQTLKYFSPVCSSVQQERSDSAEPSSVSVKSHWSIDPPPQMTERRDSLSLALQERSDSPEPSHVSMKSDWSIDPPPQMKEENRSLVQQERSPKSSCVSMKRDWSIDPPPQMNDEDGQKRLSLVQQERSDSAEPSLVSMKSDWSIDPPPQMKDGDRQKSLSLVQQERSDSPEPSHVTMKSNWSIDPPPQMTDRRDSLRQIPRPRPGAEEPISKKMKYDESVIKSQECMENPSLIFSHEVNTFRVNLLKKFQCLYEGMVTQDNPALLNEIYTELYITESESGEISNEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPETKEIDIFSDKYKILFIFDGLDECRLLLNFKSNEILQHVTKTSSVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLMAQINTKDMKYTGKKDKDMIFKLGKLAYEQLERGNVIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFIHLSVQEHLAALYVHLLFTNHNRNVFEQMTKKTSKTLDILDCFHSNSPENVLLSELHQKAVDEALQSKNGHLDLFLRFLLGLSLESNQILLQELMIKFRSSSDSSEKTVEYIKKRINNICLPEKSINLFYCLNELGDHSLVKEIQQYMDYGTLAETKISCGQWSALVFILLTVEQAMDVFELNKFIGLKKSSDEVLRKLLPVIKKSRSAIMDDCNITAEGCAYLASALGSNPSYLRELDLSANKLQDSGIKKLSKGLQDSHCKLEKLNLYHCGVTNEGCAALASALKSNPEHLRDLNLSENKIGNLGLTCLSEILKNSLCKLEILRLCQCGITDCTDLASALISNPEHLRELELSLNKIGDSGVTALCAAFEDPRFKLEKLGLSGCGLTDEGCAALTSALRSNHEHLRDLDLSGNKVDKEVKGSILQRILEKLNNIQILSV", "length": 1068 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YU37-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch73-24k9.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDNQTFSDAPVCSNESNPEFEPSCVSMKSDQSMDPPMKFKEGHTSADLSDRLNPPGSSCVSMKSDWSMDRPIQFKEEHSSADLSNKSNPGEPSCVSSKSDQSMGPPINVMEEHSAADLRLDPHLKQNGLRSNLLRKFQCLYEGTAMQGDPTLLNEIYTELYITESDSGEINNKHELRQIETRSRRSATEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEEKENQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEQFKVLFIFDGLDECRVSLDFKCDVKLHDVSESASVDVLLTNLIMGNLLPSALIWITSRPAAADLIPSEFVHRVTEIRGFNDPQKEEYFRKRIRDQFLADIIIINLKSSRSLHIMCHIPVFCWISATVLEKIFSQAQSGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEVRDEDMILKLGKLAFEQLVKGNLIFYEEDLRECGLDVTEASVYSGLCTQIFREEFGFYQGKVFCFVHLSIQEHLAALYAHHSLTNKNRNVFKQTKPSLLSKVLNQKKHDSLSVLHQRAVKEASQSKNGHLDLFLRFLLGLSLESSGTLLRELLTQTGSCSYNKEETVQYIKQKIRENRSPERSINLFHCLNELGEDSLMQEIQDYLSSGEIKETKLSSSQWSALVYVLLTSEKKMDFFDLSKFIGPQLRADVVLQKLLPVVKESRSVRLGDCKVTDKVCAALASALRLNSSHLTQLDLIGNKLGDSGVKLLSDGLKDPHCKLKNLMMRDCGVTDEGCAALASALRSNSTHLTELNLNENNLGDAGVKRLSDGLKGPHCKLEILRLWRCGVRDEGCAALASALSSNSTHLKELELSDNKLGDSGVKLLSDALKDPHCKLEKLRLNGCGVREQGCVSLALALRFNPSSHLTELDLTSNELGKSGVKLLSDLRDDPRYKLRHLACDMFGRIIVSSGGGRLDELLPTTSTET", "length": 978 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:21269", "url": "https://alliancegenome.org/gene/HGNC:21269#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkey-165e24.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHRVRSGSCVSSSVSLKSDCSKEDPPKFSEKTPSSAQSVRSGLCVSSFVSLKSDCSKEDPPKFSEKTPSSAQSDEDELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNELEKFKQILQEENRQEFVKDYNENRSRITEAALDLTLFFLREMKQDHAADTLQDELLFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAVSRRHQSLETQVEFKHLFKAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQLFPETKGLNLTRSTQFKVLFILDGLDECRLPPNFAGNEMCCDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILNLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSQGKLAFQQLERNNVIFYESDLNDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEGIIAYIKQKLEGNLSPERSINLFYCLSELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELWKFQRSDECLIRLSAIIKNSKRALLQSCNLTVQSCKSLSSILQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLATCNLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSEHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDTLNLDHVGDMRITAGPRKYVCFLTLDPNTANTQLKLSKENRKVKHVREDLRIMRKDRRYPYHPDRFDPVFQVLCRESVCGRCYWEIDWSGDHGVFISVSYKSIRRKRGDACEFGCNAQSWSLLCLSSRFTFRHNNTHTHVPVKPLSRRIGVFVDHSAGTLIFYNIYKDTMSLIHSVQTTFTEPLCPGFGFYSGSSVKLS", "length": 1137 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1F5-1", "protein_name": "Protein NLRC3", "gene_name": "si:dkey-23k10.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METEGPDSPEPSCVSLRSDHSKAHHVLFKDEDPFEYSSGQTGRSSPTPSHVSLASNMSINQPLEFKSCSNTLLLKEIQEAIQSVLRIRFQCLHEGLSKHSVLIPLNDIYTELYITEGEGGELNNEHEIRWIETACRRALTEDRPVNLNDIFKPLHGQDRPIRTVLTKGVAGIGKTVSVQKFIIDWAEGEANQDIWFIFPLPFRELNLLKDQSFSLKGLLQYFMNIELDISLHEGKIMFIFDGLDECRLPLDFHNNVKLCDVTESASVDVLLTNIIRGNLLPSSLIWITSRPAAADVVPSKCIHRVTEVRGFSDPQKEEYIRKKVSDQTLSDRIISHLKSSRSLYIMCHIPVFCWISATVLKKMLSEAESAEIPNTLTQMYTQFLMLQLRIKNEKAYDKKSSDIDIVLKLGELAFQQLEKLNLIFYKEDLREYGIDEQEASVYSGLFREESGMFQGKVYSFVHLSVQEHLAALYVYLYFVNENINKLNQPNFLTSILKCVPTVFDVYQTAVKKALQSTSGHLDLFLRFLLGFSLESNQNLLGDLQVQTESSSDSREQIVGFIKEKIKESPPPEKMINLFHCLNELNDHSLVEEIQDFLQSESRINMKLTASQWSAMVFVLLTSGQKLDVFDLNKYIGTYILPDESLQRLQPVLAASRTAKLCEHNLTKRGYSVLVSVLTSKTSCLRELNLTRSAVNDSGLKLLCSGLENPQCKLETLRLEFCGVSDKGCDFLASALRSNPSHLKALDLSGNTLNFTGLKNLLAEFQKPHCKLQRLCLRLCGLTDVGCDALASVLRSDPSHLTELNLSGNKLGDLGMKLLAGGLQNPHCKLQILRLGDCSITHEGCAALASALRSNPSHLRELDLSGNKLNNAGVQILSGELENPDCNLEILRLENCDVGEEGCAALAEALKSNPLTLKELDLCWNKLGNSGVQRLCTSLENPNCTLGVLRLTGCNISENGCAALASVLRSNPSYLRDLDLSHNDLRSSGVRLLSSALEKPDCKLEILRLEYCKITDDGCAVLASALKSNPSHLRELYLYMNSFNLTASGRQLLSKIKDDPHYKLQTLHYESHFFC", "length": 1074 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z5L8-1", "protein_name": "NLR family CARD domain-containing protein 3", "gene_name": "si:ch211-207e19.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKDFNENRSRITDAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTDHEIRQIEAASRRHQSLEIQVECKHLFEAAEQHEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETEGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVDKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNDKKQGWFFIQISKNKGMIDFLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKGEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSADLSPAQWSALVFVLLTSEEELEVFELQKFQRSDECLIRLSAVIKTSKRALLQGCYLTVRSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLQFCNLTVQCCESLSSALQSSNCVLRELDLSINDLQDSGVKKLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKYVCFLTLDPNTAHTELILSEENREVKSVRENQPYPDHPDRFDYYHQVLCRESVCGRCYWEIDWSGDGVVCISVSYKSIRRKGGGDECVFGYNAQSWSLRCDSSRFKFWHNNTHTDLPVEALSSRIGVFVDHSAGILIFYNIYRDTMSLIHSVQTTFTEPLCAGFRVYYPGSSVKLS", "length": 995 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PCI8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-121n8.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTQTTIEKDYSPRFSLVHQKRSEPSCVSIRRDQSVAHPIDFKSEDTQTHLSSVHQERLDPEPSCVSIRSDRSVAHPIDFKSKNTHLSSVHQERSEPEPSCVSIRSDRSVAHPIDFKSEDTQTHLSTFHQKRKEADPSCVSMRSDTFMNQPINIKIGETQNDLKQNLLNTFRSNLLKKFECLYEGTAVQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQNKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSEKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCLNNNRNEFEQISKQSLWSKVRDHFHFNSSKLVSISKLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQGLMKLKIRSIQNNETVEYIKKKIRKINFPEKFINLFHCLNELGDHSLVEEIQQFLKSGGMNEAKLSSSQWSAVVFVLLTSEKKLEKFDINEFAARNNNTEQLFIFKKLQPVIRQCRSVQLSYCGLTDEGCAALASALRSNPEHLRDLYLSGNKLGDSVSLLSGVLEDPHCKLETLWLSDCGLTSKDSAALASALRSNPEHLRVLDLSWNRLGDSVTLLSAVLEDPHCKLETLLLRDCGLTDEGCAALASALRSNPEHLKHLDLSWSNLGDSVTLLSAVLEDPRCKLEKLGLSNCGLAEEGCAALASALRSNPEHLRGLNLSVNNLGDSVTLLSAVLEDPRCKLEKIKLSYCGLTDEGCAALASALRSNPEHLRDLDLSTNNLGDSVTLLSAILEDPHCKLEKLELKNCGLTDEGCAVLASALRSNPEHLRDLNLSWNNLSNSTKKLLSDLKDDPHNKLETLHTSLSV", "length": 1115 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PLT8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "nlrc8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSMNHPKHFKSGETQNDLGSAHQKRSDPEPSCVSMKSDWSMNHPIKFKSGDTKNDLSSVQKRSDPEPSCVSMKSDWSMDPPMQFKSKDTPPDLSSVHQERSEPEPSCMSMNSDLPLDPPIRYKSGETQNDLSPQVFNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESKSGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFQSAVRLCDVSESASVDELLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINKSINQFNFAAKQSLWSKTKFMFKTVALSELHQRAVVETLQSKNGHLDLFLRFLLGLSVESHQILLQRPLKLKRRSIKNNKTVEYIKKKIRTIDSPEKSINLFHCLNELGDHSLVEEIQQYLKSGGINEAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAENNKTEKLVIFKKLLPVIRECRSVQLYNCGLTGEGCAALASALISNPEHLTDLNLSRNNLGDSVTLLSAVLEDPHCKLEKLWLSYCGVTDEGCAALVSALRSNPEHLRELNLSGNNLGDSVTLLSAVLEDPHCKLEKLRLYYCGLTDEGCAALASALRSNPEHLRDLDLSWNKLGDSVTLLSAVLEDPRCKLEKLELYNCGLTDEGCAALASALRSNPEHLRDLNLSGNKLGDSVTLLSAVLEDPRCKLEKLWLSDCGLTDEGCAALASALRSNPEHLTELDLSWNNLSKSTVRLFSDLKDNPHNKLKTLHI", "length": 1017 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPT2-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSKRKREDEDAASEISSASPGSSCVSVKSDQSMKKNLPDFSDASVTSDLSISKTINQRSASPEFSVLSMTSNRSIGQPENFSDEPVTFDSVLSDALDKPDYEKLHRIKDQHKTSMKNKYERLFEGLKLDETGTHLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHRASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFHVFYYHVNTTMDGLRNFASVENLIKGAVDKAIESENGHLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLFREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCGIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELNLSYNHPGQSGVQLLQHTLEDPHYTRQKLNWDHGGHFRITPGLRKYACFLTLDPNTAHNQLILSEDKRKVTHVKDPQQYTDYPEKFVHQEQVLCKETLTGRCYWEVEWSGEGTDIAVAYKGIRRKAGSDCWFGYSEKSWSLFYTGNGFNVWHNNKSQIIPAPSPLSNRVGVYLDTESGSLSFYSVSDTHTLTHLHTFNTTFTEPLYAGFRVFDSSLSLCNI", "length": 993 }, "evidence": [ { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9QCS9-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch211-15j1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSLQKKNEDEDEESASEMSYPPPESSCVSMKSDWSMVYPPDLSDASVTSDPNNSKRKGQHLEFKESSCVSVMSNRSITPPEMKKIGLKSEDNMLEKIKNKHKTSMKHKYERLFEGVKLHENQTLLNRIYTQLYILEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVGVSDASVYSGICTEIFKEESVIQQRKVYSFTHLSIQEFLAAFYVFYYHITCSTEACFDSLHDLQRRAVDKAIESENGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCQLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRITSGLRKYACFLTLDPITAHTQLQLSEENRKASIVTDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGLVAVAYKGIGRKSGFDCCFGHNEHSWCLYCSDEVYSVWDNNKSVDVFGPSSRTNRVGVYVDVPSGCLSFYSVSDTNTLTHIHTFNTTFTEELYAGFKVYPGSSVSLCPVKPAEVPP", "length": 988 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUW9-1", "protein_name": "NLR family CARD domain-containing protein 3 isoform X1", "gene_name": "si:ch211-196h16.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDHRGHRDENLPKGRPTFPHRSNPPEPSGVSMKSDRSMHHPLKFKGNTGFRVKPPEPSGVSMKSDRSMHHPLKFKGGIDPGFRVNPPEPSGVSMKSDWSMHHPLKFSGGIDPMFRPPEPSVSEKSGQSVDPTLKFSVHTCHGSSHRKPLQTFRSNLLKKFQCVSEGTARNKSPTLLNEIYTELYITEGDSGEINNEHEVRQIETQSRRSTTEDTPIQCRDIFTALPGQHKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDRTLSLADLLHVFFPETKEMEISRDGYKVLFIFDGLDECRLSLDFNSGVKLCDISESASVEDLLINLIVGNLLPSALIWITSRPAAADLIPSAFVHRLTEVRGFTDPQKEEYFRKRIRDQRLADEIIQHLKSCRSLFIMCHIPVFCWISATVLEDMMRRTDIGEIPKTLTEMYTHFLIIQTSIRHEKHYEKKLKDEEMILKLGKLAFRQLMKGNLIFYEEDLRECGIDESEASVYSGLCTQIFREELGLFQGKVFCFVHLSIQEHLAALYVLLSFLLYERDELSENFRSTRPHEFTCHTVFDLHQRAVDKALQSRNGHLDLFLRFLLGLSLKSNQTLLKNVLTQVGNISYSQEETVEYIKIRIKLNPSPEKSINLFHCLNELGDHSLVNEVQKYVRSGDLSGSRLSSSQWSAVVFILLTSEQLDEFNLRRYLTDSEHQTQTQKLQTPDEVLQKLLSVVEASRSAVLINCGVSDEGCAALASVLRSKSSNLRELNLSENKVGDSGVKRLSAGLKDPHCKLEKLRLRCCGVSDEGCAALASVLKSNSSNLRELDLSWNKVGDSGVKLLSAGLKDPHCKLEKLRLCRCGVSDEGCAALVSVLSSNSSNLRELNLTENKVGDSGVKLLSAGLKENSKLEKLWLFICGVSDEGCAALASILRSNSSNLRELDLTGNKVGDSGVKLLSAGLKDPHCKLEKLTLDFCGVSDEGCAALASALRSNSSNLRELNLFNNNLGVSGVKLLSDLRDDPHYKLETLHISWGFIC", "length": 1041 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32T552-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:ch73-50f9.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSGKHSVRSGSCVSRSVSLKSDESRKGLPPEFSEQPPSSNRSVEYELSDSVDKTHCNRKSFTDHLLRIFQDLESKIFKVLKNELERFRQILQGENTQDFVKGSNENQSSITKSALDLTLLFLREMKQDEVADTLENELLFINRLKSSLKKTYQSVSEGIAQQGDSTLLNNIYTDLYITQGANEQVNTEHEIRQIEAASRCHKSLEIQVECKHLFEAPEQDKQIRTVLTKGVAGIGKSVSVQKFVVDWAEGKANQDISLIFPLPFREMNLKEKEKQSLKDLITQLFPEVKGLNLTRRTRNKVLFILDGLDECRLPLNFAGNETCHDVSAPAYLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLADQNLAMEIIEHIKQSKSLHIMCHIPVFCWISATVLQNVLKETKVKHKACAKTLQESPKTLTQMYTHFLRFQMQQSRQKYDGKNTDGVSWDQNFILSLGKLAYQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKQETGIILGNLYCFLHLSIQEFIAALYGHLYLDIKKKSVFTGQKHKNKGMTHLLKTAVDKALESDNGHLDLYLRFLLGLSLQTNRQLLRGLLTQQDKSDQSKEEIVVYIKQKLEENLSPERAINLLYCLNELNDHSLMKEIQSHLRDGSLSSADLSPAQWSALTFVLLTSEEELDEFDLQKFKKSDECLIRLSAVIKSSKRALLQCCNLTAQSCESLSSALQSSNCVLRELELSNNDLQDSGVKLLSCGLRSLNCPLEILRLQCCNLTAQSCESLSLALQSSTCVLRELDLSNNDLQDSGVKLISNGLKSCKLEILRLSGCMVTETGCGFLSSALSSNPTHLRELDLSYNHPGVSGVKLLCQKLEDPNYTLAKLNVDHAGAKRITAGPRKWISHLTLDPNTANTELSLSAENREATRVIEKQPYPDHPDRFDYHPQVLCRESVCGPCYWEIDWSGDVGACISVSYKSVSSKGNDEFGCNDQSWSLSCYSSRFSYGHNNRWTDLPVKPISRRIGVYVDHRAETLRFYNICGNTVHLVHSVRTTFTQPLYAGFKIYPGSSVKLC", "length": 1099 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TA29-1", "protein_name": "NLR family CARD domain containing 9 isoform X3", "gene_name": "nlrc9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTKISKDEDYSPRFSSVHQERSDLEPSCVSMRSEQSMGSPMHFRSEDTEADLSSVYQKRSDPEPSCVSMRSDWSMDLPYNFRSEDTPTDLSSFHHKRTEAEFSRVSMRSDMFINHPINIKNVEAQCNIRQNLLNTFRSNLLKKFECLYEGTAAQGNPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLMKDKTLSLSDLLQLFFPQTKEMEISSDKYKVLFIFDGLDECRLSLDFESAVRLCDISESASVDVLLTNLIVGNLLPSALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPMFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILKLGKVAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLSCINNNRDEFEQIKKQSLWFKVKDLFQLNSLECVSLFSLHQRAVNEALQSKNGHLDLFLRFLLGLSVESHQILLQRLMKLKSRSMQTNKTVKYIKMKIWTIDSPEKSINLFHCLNELGDHSLVKEIQQYLKSGRINRAKLSSSQWSAVAFVLLTSEKKLEEFNINEFVAGNNENKKQKVFQKLLPVIKQSRSVLLYNCGLTEMDWDNLTSALRSNPSDLRVLNLSRNILGNSVTLLSAVLEDPCSKLEKLWLSDCGLTDEGCAALATALRSNPEHLRELNLSWNNLRDSVTLLSAVLEDPRCKLETLWLSKCGITGKSCAVLASALRSNPEHLRDLDLSGNKLGDSVTLLSAVLEDPHCKLKILWLSDCGLTDEGCAALASALRSNPGQLRVLDLSENKLKNSGVMQLCAVLEDPHCKLDKLGLYDCSLTDEGCVALASALRSNPEHLRELDLSVNKLRDSGIKLLSAVLEDPRCKLEKLWLSNCGLTDEACAALASALRSNPEHLRELNLSKNKLGESDVKLLSDLKDDTHYKLKELNY", "length": 1079 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:21269", "url": "https://alliancegenome.org/gene/HGNC:21269#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TJY6-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like isoform X1", "gene_name": "si:dkeyp-100h4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQQIQETRLKGDTRASQTISSPSSSCSMAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKDCPPVFSGETPSSAQSVEFESADSGDETHRRHKSFTDNLQSIFQNLESKMFTFLKNELEKFKKILQENRQEIVKEFNENRSRITEAALDLTIFFLREMKQDQAADTLVGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVKCKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDDQKQEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGFVLHTMYCFLHLSIQEFIAALYQHLILDNDKTQAEKSRDESMIDLLKAAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEANLSPERSINLFYCLNELNDQSLLKQIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAIIKTSKRALLQGCYLTVPSCESLSSVLQSSNCVLRGLDLSNNDLQDSGVNLLSDGLKSQHCKLETLRLVMCNLTVESCESLSSVLQSSNFVLRELDLSNNDLQDSGVKLLSDGLKTVNCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVELLFEKLADPNYTLDKLNLDHGGHTRITAGPRKNACFLTLDPNTTYAFLILSEENREVKTVREYQLYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDDYVDISVSYKSIMRKGVDPECVFGRNAQSWSLCCDSSSFTFWHNDTDTRLPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLWPGFTVWCQSSVKLC", "length": 1125 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TMV3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3-like", "gene_name": "si:ch211-197e7.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDWSKEDPPKFSEKTPSSAQSVRSGSCVSSSVSLKSDRSKEHPLPNFREKTPSSAQSVEHELPDSGQETHRNHKSFTDNLQSIFQNLESKMFRFLKNEMEKFKKILQEENRQEFVKDYNENRSRITEAALDLTLFFLREIKQDQAADTLQDELFSINQFQCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNNEHEIRQLEAASRRHQSLETQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNKTCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKILFIMCHIPVFCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNESMINLLKTAVDKALENENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDESKKKIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSRGSLSSARLSPAQWSALVFMLLTSEEELEEFELRKFQRSDECLIRLSAVIKTSKKALLQSCNVTVQSCKSLSKVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLAMCNLTVQCCESLSLALQSSNCVLRELDLSNNDLQDSGVKLLSNRLKSQYCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEKWQCPNYTLDKLNLDHGGEKRITAGLHKYVCFLTLDPNTAHIQLILSEENRKVKPVREDMMMMRKDQPYPDHPDRFDGLYPQVLCRESVCGCCYWETDWSGDGGVCISVSYKSIRRKGGVECEFGRNAQSWSLHCSSSRFIFIHNNTETRLPVKRLSKRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRVYSGSSVKLS", "length": 1140 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TPE7-1", "protein_name": "Protein NLRC3 isoform X4", "gene_name": "si:dkey-11n14.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKYSVRSGSSSSVSLKSDWSKDEPPKFSEKSPSSARSVEYELPYSGDKTHRSHKGFTKDLPRIFQNLESKIIRYLKNELEKFKKILQEENRQDFVKHFNENRSIITEAALDLTLFFLREMKQDEAADTLEGELFFINQLKCGLKKKYQNVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTTGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLMEKENQSLKDLITQFFPQTKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTKLIKGNLLPSALIWITSRPAAANKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISANVLLNILKENRNTELKHRDNSETLHESPKTLTQMYTHFLRFQIQHSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYDSDLKDCGIDVYKASVYSGMCTQIFWEETGIILGTMYCFLHLSIQEFIAALYQHLFLDSDKKHLSIFRQKSKNKVMTDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQNDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSADLSPAQWSAVAFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQGCNLNVRCCESLSSALQSSNCLLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDTLNLNHGGEKRITAGPRKYVCFFTLDPNTANTRLILSKKNREVKCVRENQSYPRHPDRFDDHPQVLCRESVCGRCYWEIDWSGGNEVCISVTYKSIRRKRGYECRFGYNAQSWSLICSSSRFSFTHNDTHTDLPVKPFSRRIGVFVDHCAGTLIFYNIYRDTMSLIHSVQTTFTEPLIPGFWVYSGSSVKLLKTEERFTQNPLQDQ", "length": 1060 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQ28-1", "protein_name": "Protein NLRC3-like", "gene_name": "si:ch211-226o13.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDTHTSGDLDLFTSCSVDGDDQTRDLQQDSLQPEHDELQRAKNQHKTSMKNKYERLFEGINHGETQKFLNRIYTQLYIIEGESEGVNREHDVLQIEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQGVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTESSSVAVLMWSLLKGDLLPSALIWITARPAAAHQIPSTYIHRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDQEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFHCYLTDKREPVMLLYESKYSDDEDVSDGNEYEDSDVQFLQSSSEFSLCHLLSLAIYKAVMSSNGHLDLFLWFLLGVSLESNQRLFQDLLTHTEESSESIRIITQDIKDKIKTDDDLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSERELSPAHCSTISYMIEMSEEPLDELDFNKLNTSPVGRWRLIPAVRNCRRALLQWSYLSVQYCESLFSALKSSNCVLRELDLSTNDLQDSGVKLLSDGLKSPNCKLETLRLQCCNLTAQSCESLTSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCKLETLRLVMCNLTVQCCESLSLALQSSNCVLRELDLSNNGLQDSGVKLLSDGLKSQHCKLDTLRLVMCNLTVQSSESLSSALQSSNCVLRELDLSTNDLQDSGVKLLSDGLKSQHCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGLHKYACFLTLDPNTTYAFLILSEENREVKRVREYQQYPDHPDRFDGIYPQVLCRESVCGRCYWEIDWSGDGCSVCTAVSYKSIRRKGRGAECLFGRNAQSWSLCCSSSSFIFRHNYTRTELPVKPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFTVWCQSSVKLC", "length": 1145 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQA8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3 isoform X1", "gene_name": "si:dkey-29j8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEEQVKDSLSEKQSVRSGSCVSSSVSLKSDNSKGGRTPNFRGKTPSSVKRFFHLGKSKHPPSNLREKTPSSAESFQYELPDSRNKTHRSQKSFRGHLQKIFENLESKIIKFVKKELKNFRKILQNENRQEFVKEFNENSSGITEAALDLTLFFLREMKQDQAADTLQGELLYINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDEQIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSVVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDTQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVLCWISATVLQNILKLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLILDNNKKQAEKSRNKVMINLLKTAVDKALESENGHLDLYLRFLLSLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKQIQSHLSRGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQCCNLTVQCCESISSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQQCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGEKRITAGPHKYVCFLTLDPNTAHTRLILSEENREVKCVRENQPYPDHPHRFDYYLQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGAECAFGRNAQSWSLICSSSSFTFRHNNSHTDLTVKPLSRRIGVFVDHSAGTLIFYDIYRDTMSLIHSVQTTFTEPLCPGFYVSYGSSVKLS", "length": 1064 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TQT1-1", "protein_name": "LOW QUALITY PROTEIN: uncharacterized protein zmp:0000001020", "gene_name": "zmp:0000001020", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSAEDVFVCVGPKSSASSCVSVKSDGSMRHPPDLSEETCNIRQEESRTASCPEPSCVSMKSDGSMRHPPDLSAEPATSEPLNKSLVRTRQRSEPSCVSVKSDGSMRHPPDLSAEAVTSDHLVDRDDQTNTLKRVSRQQVDQLQQVKDEHKASMKDKYESLYEPVKLQDNQTLLNSIYTQLYIIEGESEWVKDEDFEKSPTAQQSQDTLIYCNDIFKTSSQVKDEIRVVLTKGIAGIGKTVSVQKFILDWSEGRANQDVDFLFVLPFRELNMIKDHQYSLHSLLRDFHPKLQNLDSRIYEQCRVVFIFDGLDESRITLNFSDCEKVCDVNESSSVGVLTSNLIRGDLLPSALIWITSRAAAASQIPSKYINRVTEIQGFDEPQKREYFTRRIGNEEQANTIISHVRKARSLHIMCHIPVFCCISATVLENIITRGSEIPQSLTEMYIHFLLIQIHVNNQKYEERDPEKVLESNRGLIVKLAELAFRQLMKGNVMFYEEDLTESGMDIDAAVYSGICTAFKQELVIQQRKVYSFIHLSFQEFLAAFYAFYCHLTKNRKPLQEFLREEYSQQDRKSPRSSLYELLTSAADKTLKSKNGRLDLFLRFLLGISLESNQRLLKDLLTHTESSTDTIGETAQYIKQRVNCYNLSADRSINLFLCLLEVNDQTLSREIQEFIRSDKHSEEKLSPVHCSAIAHMIQMSEEVLEEFEPIKYNTSYEGRWRLIPAVLNCRKALLTGXCLSDEHCDSLSSALQSANSHLIELDISTNDLLISGVSQLCDALKSSHCQLRILRLAGCRLSDQDCKSLSSVLQFPNSPLRELDLSNNDLQESKLELLCAGLEDSHCQLNTLRLSGCCLSDKHCGTLASALQSSNSCLRELELSNNDVQDSGVKLLSAALKSSHCQLNTLRLAGCRLTGQCCESLSSALQSSNSKLRGLDLSNNNLQDSGVMLLSAGLKSSRCQLETLRLAICDLTGVSCESLSSALQSTECLRELDLSNNDLQDSGLKRLSAGLESLHCQLETLRLSGCMVSEDGCRYASAALSSTHSRLTELDLSYNHPGASGVSLLSDLQKNPNSALDKIHVDHGGEFRITAGLWKYACDLTLDPKTANSNLTLSEDSRKVTYVEEKQSYPDHPERFDGWPQVLCREGLSGRCYWEAEWTGYAVISVAYKAIWRKGWNEFSEFGYNRNNRNSWSLICDEAFTACHDHKETVIRVPSSSWRRVGVYVDCSAGTLSFYSVSNTLTHLHTFTCKFTEPLYAGFGIYRLNSSVSLCKFEATHIHARD", "length": 1281 }, "evidence": [ { "id": "HGNC:21269", "url": "https://alliancegenome.org/gene/HGNC:21269#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TTK4-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "nlrp3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEAMNRLMTDMLEELVEAELKQFTRQLWMGVKPGVDPIPRGKLENKDRQDVVDCMVQHYSKDAGKIAVQALRSIKQNERADRLELNLRKDDDFLGEVLKKHKESIKASVDVFEGKKDNKTDINKVYTELFITEGDMTDVCKEHEVQKFDLALQMPRSEDKPIDCNEIFNLLRGKDKGNVVLTKGIAGIGKTFSVNKFILDWAEGRANLDVDCMFLLPFREINLMIKDGDVSLHKFLLKLFPDITGVETTPFYEKCKLLFIFDGLDESRLDLNFNLSSVDDVHSCASIDGLFTSLIKGRLLRSSLIWVTSRPAAANRIPSYHVGLFTEVRGFTDKQKEEYFRKKVPDEDQASRIISHIRTSRSLYIMCHIPVFCWIIATVLQDILQKNKGEDIPSTLTEMYIHFLLIQMNIKNQKYDEKLIRDRTELLGSNRDMISKLAKLAFEQLKKENVMFYREDLAACGINADEEFTGLCTEIFKKDSVLHELKVYYFIHLSVQEFLAALHVFLCYLELEKDMNLTDSDLMFFLEDSRPKQKELLHVLLRKAIDKAEKSDRGHFDLFLRFLLGISLESNQKLLIGILNETKNSKQSISKTVQYLKQLQNNDKCPDKSINHFFCILELQDRTLYQQIMKYLRSKTNRPKVMSRSNCSALVYVLLMSQEVLDKFNPKLFNKTYAGCRILVPAVRCSRKALFSDCGLTETCFETVALALQLENCPLVELDLSYNYSLEAAVNVMCAGLKSPHCHLESLRLAGCHLGQDSCMQVVSALQSISHRLKELDLSGNDLQDSGLQKLLQGMENTEKRLQVLRLSWCNLTEMSCQQLSTILSSNSVFRELDLSNNDLQDSGVKLLSDGLKSPNCKLKILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHCKLKTLKTDPMGDHLMKPGIVKYAFNLTLNPNTAHVHLLLSDGDRKVTLKEKQPYPDDPERFEEHHQVLSRESLSGRCYWETEWTGQEGTVGVAYESIPRKPDDLLYGRCMLGNNIISWKITCGSRTHVSHAEEDITVKSPSSGSCKRVGVYVDTTAGVLSFYHVFDTLTHLYTFLMPFTQPLYAAFRVDGESVSICPIP", "length": 1114 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TUF4-1", "protein_name": "Protein NLRC3", "gene_name": "si:ch73-236c18.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHHCGNEEVDREEKEKHGAEHSCVSMKSDQSMRNPIAFTDKAVTFDLRSVASSSSHFETHTVQEKTDKGLQTQIFETEELQRVKDQHKTSMRKKYELLSEGIKVKETGTQLNRIYTQLYIIEGESEGVNEEHEVLQMEKTARTKHSQHTPIYCNDIFKEEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFMFVLPFRELNLIRDHQYSLHTLLLDFHPELEDLEPKIYEECKVVFIFDGLDESRITLMFSDAQKVCDVTETSSVAVLMSKLMKGELLPSALIWITSRPAAANQIPSKYIKRLTEIQGFTEPQKEEYFRKRISEQHQASRIISHIRRARSLHIMCHIPVFCWISSTVLQKLLEEDLSAEIPQTLTEMYIHFLLIQINMRNQKYEERDPEKLLQSNREVIVKLAEVAFRQLMKGNVMFYEEDLIESGVDVSDASVYSGICTEIFKEESVIQQRKVYSFIHLSVQEFLAAFYVFYYHVNTTMMGLKTFASLQKLLKGAVDDAIESKNGRLDLFLRFLLGVSLESNQRLFQDLLTHTEKSSESIRRSTQYIKEKIRDGHGLSTERSINLFLCLLEVKDQTLSREIQEFVKSDKQSEKKLSPAHCSTIAYMLQMSEEVLDELELQKYNTSDEGRRRLIPAVSNCTRALLAGCNLSAQDCEIVSSVLQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSPNCRLEILRLSGCMVTEEGCGFLSSALSSNPSHLRELDLSYNHPGQSGVQLLQHTLEDPHYTLQKLNLDHGGHFRIKPGLKKYACFLTLDPNTAHVQIQLSEGNREARNVKDPQPYPDHPDRFDQQEQVLCRETLTGRCYWEVKWSGSGHIGVAYKAIDRKSGLDSWFGLNENSWSLYCCDTNYTVWYNNESADIIAPSARTNRVGVYLDVSSGSLSFYTVSDANTLTLIHTFNTTFTEPLYTGFGLYPESSVSLCQI", "length": 969 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LF28-1", "protein_name": "NLR family, pyrin domain containing 5", "gene_name": "Nlrp5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPPEKDDKAKPRDEDSEKEQISESTMTPPRKDDEAIPKDEGSEKEQTTETKMTPPEKDAEMVTKVKGPEQEQTTESPTTPPKKDDKATPKEEGSEEEQKPPESPTTPPKKDDKATPKEEDSEQEQKSPESTITPEKDDKGTQKDEGSEEEQPSSESPTTPPKKDDKATTKEEGSEEEQKPPESPTTPPKKDDKATPKEEGSEKEQKSPESTTTPPKKDDKATPEEEGSEKEQKSPDSPTTPPKKDDKATLNEEGSEKEHKSPESTTPPKKDDKATPKEEGSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKSPESTTPPKKDDKATPKEEGSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKSPESTTPPKKDDKATPEEERSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKPPESTTPPKKDDKATPKEEGSEKEQKSPESPTTPPKKDDKATPKEEGSEEEQKPPESTTTPPKKDDKAIPKKEGSEEEQISPESKTTPPEKGAKMIPEFQGPEQEQTSESPTTPPKKDDKAIPKDEGSEKEQTSESKITPEKSDKASPKDKGSEEEQTSESKITPPRKDDKAIPKGERSEEEQTSPESKITPEKSDKASPKDKGSEEEQTSESKITPPRKDDKAIPKEERSEEEQTSSESTTTPPKKDDKAIPKKEGSEEEQISPESKTTPPEKGAKMIPEFQGPEQEQTSESPTTPPKKDDKAILKDEGSEEEQISESKITPPRKDDKAIPKEERSEEEQTSSGLAEERIVTPEKHDKATQKDQGSEEEQIPESTTTPPEKDDEAIPKDEGSEEEQISDYKAHVIAKFDTSVDLHCDGPEMKVLSDAFKPHQKTFRPHTIILHGRPGVGKSALARSIILGWAQGKLYQDMSYVFLFSVREMKWTEKSSLAQLMANEWPHSQAPVTKIMSQPERLLFVIDGLDDMDSALQHDDMTLSRDWKDKQPIYILVYSLLRKALLSQSFLIITTRNTGLENLRSMVVSPLYILVEGLSASRRSQLVLENIPDDHQKIQVFHSVIENHQLFDQSQAPSFCSLVCEALQLQEKLGKRCTLPCQTLTDLYATLVFHQLTSRGPSQRALSKEEQITLVGLCRMALEGVWTMRSVFYDDDLKSYSLKQSEISALFHVNILLQVGHSSEQCYVFFDLSLQDFFAALYYVLEGLGEWNQYFSYITNQRNIMEVKRSSDSHLLEMKRFLFGLMNKDTLKTVEVLFRCPVTPPIKQKLQHCLSLIGQQVNGSSPMDTLDAFYYLFESQDEEFVHMALKSFQEVWLLINQKMDLMVSSYCLQQCQNLKAIRVDISDLFSVDNTPKLCPVALQKTQCKPLIIEWWENFCTVLSTHPNLKTLDLGHSILNEWSMKILCLKLRNSSCSIQNLTFKNSEVVSGLQYLWMLLVSNRNLKYLNLGNTPMKDDDIKLACEALKHPSCSLETLRLDSCELTLTGYELISKLLLSASSLKCLSLARNKVGVKSMTSLGEALSSSTCTLQKLILDGCDLIPVSCHMLTSALSSNRNLTHLCLSNNSLGTEEVQQLCQFLKKPECALRRLILNHCNIIKDAYGFLALILANNRKLTHLSLTMNPVGNSAMKLLCEALKEPTCYLQDLELVDCQLTENCCEDLACMITTTKHLQSLDLGNNALGDKGVITLCKGLKQSSSSLRRLGLAACGLTSKCCEVLSSALSCNPYLNSLNLVRNDFNTSGMLKLCSAFQNPASNLWIIGLWKQQFYAQVRRQLEEVQFIKPHVVIDGDWYSIDEDDRNWWKN", "length": 1778 }, "evidence": [ { "id": "HGNC:21269", "url": "https://alliancegenome.org/gene/HGNC:21269#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58HZJ9-1", "protein_name": "Uncharacterized protein si:ch211-149a19.3 isoform X1", "gene_name": "si:ch211-149a19.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDKEASNDGDFSSRRSHFQSQKSNTSESNPEITPEDLSAKKLIKMFEKRTPDNQSKFNNQKSNTAKSIRSDRSIQNPVKIKEIRTPADLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPKPMPRSIKSDQSTPELDKVDGGHTSTALSSQRSNPPDPKPRSIKSDQSTPEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGIGCQRSNPPDPKPRSIKSDQSTLEPDKVDGGHTSTGLSSQRSNPPESSSVSMKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSTLEPEKVDGGHTSTGISSQRSNPPESSLVSLKSDQSTLEPDKVDGGHTSTGISSQRSNPPESSSVSMKSDQSMPEPIKFDGGHTPTGLSETSTNDQFMNKQVKIKRRHTLTGLSKTSINYQFMEKQLKTERRHTSTGLSLNSKLFENLLKSNLLKKFQCVSEGTSILGNPTLLNEIYTELYITESDSGEINNEHELRQIETQSRRSAKEDTPIQCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFIVDWAEKNKNQDIQLIFPLPFREINLMKDRTLSLSDLLQVFFPETKEMEISSEHYKVLFIFDGLDECRVSLDFDSGVKLHDVSESASVDVLLMNLIMGNLLPSALIWITSRPAAADLIPSGFVHRVTEVRGFNDPQKEEYFRKRIRDQSLADTIISHLKSSRSLHIMCHIPVFCWISATVLEKIFSQAERGEIPKTLTQMYTHFLIMQTNIRHEKDYEEEDKDMILKLGKLAFEQLQKGNLIFYEEDLRECGLDLTEAAVYSGLCTQIFREEFGFSQSKVFCFVHLSIQEHLAALYAHHFLTNNCLNKHWKTFNPLSFLHQRAVNEALQSKNGHLDLFLRFLLGLSLEFNQTLLQELLTQTGSCSYNTEETVQFIKQKIREINSPERSINLFHCLNELGDQSLMKEIQNYLRSGEIKETKLSSSQWSALVYVLLTSEQEMEDFDLNQFIGTQNTADEVLQKLQPVVKESRSVQLSGCSVTDKGCAALALVLRSDSSHLRELDLSENNLRDSGVKLLSDGLKDPHCKLEKLRLSDCGVTDEGCAALASALRSNSTHLTELDLSLNNLEDSGVKLLSDGLKDPHCKLEILRLSDCGVTVEGCADLASALRSNSTHLRELDLTLNNLEDSGVNLLSAGLKDPHCKLEKLRLSDCGFTDEGCADLASALRSNSTHLTELDLSLNNFGDSGVKLLSDGLKDPHCKLEKLRLSYCRVRAEGGVALASALRSNPEHLRELDLSENKLGNSGVKMLSELKNDSRYKLDTLKF", "length": 1375 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:21269", "url": "https://alliancegenome.org/gene/HGNC:21269#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCJ8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12-like isoform X1", "gene_name": "si:dkeyp-77c4.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDRSKEEHLPNFREKTPPSAQSVRSGSCVSSSVSLKSDWSKRDPPNFREKTPSSAKSSVHQKRAEAEPSCVSMKSDWSMNRPITFRSKITQPAISVDRDDQTGHLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEKIKKEKAQIKTVLTKGIAGIGKTVSAQKFILDWAEEKDHQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPELEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCALTESSSVAVLMWSLLKGDLLPSALIWITSRPAAAHQIPSRYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQIHMRKQKYEERDPEKLLQSNRGVILKLAEVAFSQLMKGNVMFHEEDLTESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVLYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLESNQRLFQDLLTHTEESTESIRRITQHIKDKIKRDKRLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELSPAHCSTISYMIEMSEEPLDELDFNKLNTSAEGRRRLTAAVRNCRRALLQGCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLETLRLQWCKPTVQSCESLSSALQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLVMCNLTVQCCESLSSALQSSNYVLRELDLSNNDLQDSGVKKLSDGLKSPNCKLETLRLVMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKRNCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGETRITAGPRKWVCFLTLDPNTAHTQLILSEENREVKRVRENQPYPYHPDRFDVHRQVLCRESVCGRCYWEIDWSGDVGVCISVSYKSIRRKGRGVECWFGYNAQSWSLICSSSRFSFRHNHTDTDLPVEPLSRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFTVYSGSSVKLS", "length": 1235 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCK2-1", "protein_name": "Uncharacterized protein si:dkey-26m3.3 isoform X1", "gene_name": "si:dkey-26m3.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGYVFVLSSLCPVFILLQFLLEFLLEIKLFRSIMGNTHAAGDQDLSTECSSVHQKRAEAEPSCVSMKSDASMGVPITFKSENTGPAVSSVHQKRAEAELSCVSMKSDASMNPPIEFKSGNTGPAVSVDRDGQTGDLQQDSLQPEHDELQRVKEQHKTSMKNKYERLFEGINHGETQTLLNRIYTQLYIIEGESEGVNEEHEVLQMEKRARTKPSQHTPVYCNDIFKASAGAGHEEQIKKEKAQIKTVLTKGIAGIGKTVSVQKFILDWAEGKDNQDVDFMFVLPFRELNLIRDHQYSLHRLLLDFHPKLEDLEPKIYEQCRVVFIFDGLDESRITLNFSDEEKVCAVTEPSSVAVLMRSLLKGDLLPSALIWITSRPAAAHQIPSTYIKRLTEIQGFTEPQKEEYFRKRISDEHQASRIISHIRRARSLQIMCHIPVFCWISSTVLQKLLEEDVSAEIPQTLTEMYIHFLLIQINMRKQKYEERDPEKLLQSNRGVILKLAEVAFRQLMKGNVMFYEEDLIESGIDVTDASVYSGICTEIFKEESVIHQRKVYSFIHLSFQEFLAAFFVFYCHLTENREPLRVIYDSEYSYNQYLQSSSEKSLYDLLSSAVVKAVWSSNGHLDLFLRFLLGVSLDSNQRLFQDLLTHTEESSENIRRITQYIKDEIKRGKHLSAERSINLFLCLLEVKDQTLAREIQEFVKSDKHSEEELTPAHCSTISYMIEMSEEPLDELDSNKFNTSDVGRRRLIAAVRNCRRALLQRCELTVQCCESLSSALQSSNCVLRELDLSNNDLQDSAVKLLSDGLKSQHCKLETLRLMTCKLTADSCESLSSALQSSNCVLRELDLSNNDLPDSGVKLLSDGLKSQHCKLETLRLQWCKLTVQCCESLSSVLQSSNCVLRELDLSNNDLQDSGVKKLSDGLKSQHCKLETLRLAMCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKTVDCKLETLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKYVCFLTLDPNTANTRLILSEENREVKHVRENQPYPDHPDRFDGVYQVLCRESVCGRCYWEIDWSGDDGVCISVSYKSIRRKRGGVECWFGSNAQSWSLSCSSSNFSFRHNNTRTDLPVKALNRRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLCPGFRIYPGSSVKLS", "length": 1239 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JCL0-1", "protein_name": "Uncharacterized protein si:dkey-165o8.1 isoform X1", "gene_name": "si:dkey-165o8.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEERVKDSLSEKHSVRSGSCVSSSVSLKSDQSKDHPPYFREETPSSAESVEYESADPGDETHRRHKSFTDNLQSIFQNLESKIIRFLKNELEKFKKILQEENRKEFIKEFIENRSIITEAALDLTLFFLREMKQDQAADTLQDELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNKIYTDLYITQGASEQLNTEHEIRQIEAASRRHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFFPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCGDVSSAVSLDVLLTNLIMGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILRLKHRAHAETLQESPKTLTQMYTHFLRFQIQQSRRKYDGENTADVSWDPNLILSLGKLAFQQLDRNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKEETGIILGTMYCFLHLSIQEFIAALYQHLDIDKKRGWFLIQISKNKSMIDLLKTAVDKALESENGHLDLYLRFLLGLSLQSNRQLLRGLLTQQDDRDQSKEEIIAYIKQKLEGNLSPERSINLFYCLNELNDQTLLKEIQSHLSSGSLSSARLSPAQWSALVFVLLTSEEELEEFELQKFQRSDECLIRLSAVIKTSKRALLQFCNLTVQCCESLSSALQSSNCVLRELDLSNNDLQDSGVKLLSDGLKSQHCKLDTLRLSGCMVTEEGCGFLSSALTSNPSHLRELDLSYNHPGDSGVKLLSEQLEDPNYTLDKLNLDHGGHTRITAGPRKCRTTHTQTHTHTHTHIHTHTHTHTHIHTHTHTHTHTHTRAHTHTHTRGLQQDRANVGPHTYTHTHTHTHTYTYTHTHTHTHTHTHTHTRITAGPRKCRTTHTHTHTYTHTHTHTITHTHLHIHTHTCTHTHTCAHTHTHIHTHTLTHTRTYTHTHTHTLPLTHTHTHTLSHTHTHTHTNIHTHSLTHTNIHTHSLTHTNKHTHSLSHAYTHACMHALSHLHTHTHALTHTHTHTHTHSLTHTHICTHKHTHTLSHSHKHSHTHTHTHTHTHTHTQARAHLHKHTLSHTHTHIHIYTHTYKHTHILSHTHAHTHTHTQARALTQTYSLTHTHTHTHKHTLSHTHTHIHHTHTQIHIHSHKTHTHARTHTLSLSLTHTHTHTHTHTHTHTHTHTHTHTQLWL", "length": 1266 }, "evidence": [ { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A1Z7N0-1", "protein_name": "Leucine-rich repeat-containing protein 34", "gene_name": "Dmel\\CG8197", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCDVLLPCEYNPKECPSPAAEKSRLFTILLLYCWQREYDKRPYRQFQFKRLTFEERIGRRYHCIRDLRIIVNYLLRRPQLSVQISSLVVSNWDAGLLKDFVRSLLPVWYIELRLMRFPREFFVMLRLNAAKMNVSQLSLEGTPLTDEDVRILREFLLVSKTLRRLNVSSCSLTQFNFALIADGVYKSPGVRRLSANRLLGMSLSLDTEKISSVLSSLLMQNTLWALSLEHCELTAQDMIPIAEHLARTNSKFRRLRIACNKIGPDGAFFLLRGMSMGGNLELLDLSYCSIGTHGGEWVAKYLASCRRLQVLHLNYNDMGPTAVNLILLAMKKQCKLEKLTLYGNHFDSRTAMIVRRLLDAEVVLHSELDISYTYDEALQDYRVVPWR", "length": 387 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:21269", "url": "https://alliancegenome.org/gene/HGNC:21269#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZAD9-1", "protein_name": "NLR family, pyrin domain containing 9", "gene_name": "Nlrp9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVDTSGYGLLKHLRKLSDGEFWSFKELLRKEPEKFKLKPISWMKIENASKEELVMLLNTHYPKQAWDMALSLFLQVNREDLSIMAQKKRRYKQTKYKKFMKTTFQSIWTLESNICIPDRSYHLIVEHQYRKLQNIFDSESEPVTAVVTGPTGEGKTVFLRKAMLDWASGILWQNRFQYVFFFSVLSLNNTTELSLAELISSKLPESSETLNDILSDPKKILFILDGFDYLKFDLELRTNLCNDWRKILPTQIILSSLLQKIMLPESSLLLELGHISLPKIFPLLQYPRDITIQGFSERCLKTYFISFFNTEKGIEVFENLKSNQMLKLCSNPYLCWMFCSCLKWQFDREEEAYFQAKTDSVFFTSFMVSAFKSAYASNPPKQNRAQLKSLCTLAVEGMWKQLFVFDSEDLRRNGISESDKAVWLRMKFLQNHDNHIVFYHPTLQLYFASMFYFLKQDKDTHVPVIGSIPQLLRKIYARDHTQWLQIGIFLFGLATEQVASLLKPYFGFIQHRDVRQEVMRYLKSLSQRECCEKLERPQNLFACLRDNKEEKFVREVVDLFEEITVDITNSHVLSIIANHLQKSSKLKKLHLHIQKRVFLEIHDPEYSDSETFTQDKKNAAEYWKKLCHIFVNLHVLDLDSCNFNKQVIEELCNVLSPSPKIPLMAFKLESLLCSFMTNFGDGSLFHTLLQLPHLKYLNLYGTNLSNSRIENLCSALRRSTCKVEELLHSEMSFPLSTDFIVSHKFGLGKCDISSEACGIIATSLMNSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLETLMLSYCCLTFIACGHLYEALVSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCILKELWLSGCFLTSECCEEISAVLTCNNNLKTLKLGNNDIEDTGVKHLCEALSHPNCKLECLGLDLCKFTSDCCEDLASALTTCKTLNSLNLDWKTLEHSGVVALCEALNHKKCNLKMLGLDKSAFSVESQTLLQAVEKKNNNLSILHYPWVEEERKKRGVRLVWNSKN", "length": 1022 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZP31-1", "protein_name": "NLR family, pyrin domain containing 4", "gene_name": "Nlrp4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEILQLRLKQISWTKVKKASREDLANLLLKHYEEKQAWDMTFKIFQKMNRKDLIERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKAQDLFKQKFTQDDCDRFENLLVSKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGIVFQNKFSYIFYFCCQDVKQLKRASLAELISREWPNASAPTAEILSQPEKLLFIIDSLEVMECNMSERESELCDNCTEKQPVSLLLSSLLRRKMLPESSFLISATPETFEKMEDRIECTNVKIITGFNENNIKMYFRSLFQDKNRTLEAFSLVRENEQLFNVCQVPVLCWMVATCIKKEIEKGRDPVFICRRTTSLYTTHIFNLFTPQNAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFSEEALRRNGILDSDIPTLLDRRILERSKESESCYIFLHPSLQEVCAAVFYLLKSHLDHPSQDVKSVEALLFTFLKKAKVQWIFLGCFLFGLLHESEQEKLEMFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEAFLMQAMNCMEQINFVAKDYSDVIVAAYCLKHCSTLKKLSFSTQNILSEEQEHSYTEKLLICWHHMCSVLISSKDIHVLQVKDTNLNETAFWVLYNHLKYPSCTLKVLVVNNVTFLCDNHLFFELIQNQRLQHLNLSLTFLSHSDVKLLCDVLNQAECNIEKLMIAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLCKALCHPDCILKHLVLANCSLSEQCWDYLSEVVRRNKTLSHLDISSNDLKDEGLKVLCGALTLPDSGLISLSVRHCLITTSGCQDLAEVLRHNQNLRSLQVSNNKIEDAGVKLLCDAIKQPNCHLENIGLEACELTGACCKDLASAFVHCKTLWGINLLENALDHSGLVVLFEALKQQKCTLHVLGLRITDFDKETQEFLIAEEEKNPYLSILSNV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZUH1-1", "protein_name": "NLR family, pyrin domain containing 4A", "gene_name": "Nlrp4a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLGLKQVSWTEVKKASREDLASLLLKHYEEKQAWDMTFNFFQKINRKDLIKRAKREIDGYPKLYRAHLKTKLTHDSSRIFNINIQDFLKEKFTKDDHDRFETLLQSKGTESKPQVVVLSGVAGIGKTLMLKRLMLAWIEGLVFPYKFSYIFYFCCQEVKQLKTASLAELISREWPDPSAPIEEILSEPEKLLFIIDSLEGIECDLFKCDSELCDNCMEKQPVNILLSSLLRKKMLLEASLLISTTPETFEKMEDRIEYTHVKIITGLNESDIKMCFHRLFQDRNRAQEAFSLVRENEQMLTICQVPVLCWMVATCLKTEIEKGRNLVSTCRRTTSLYTTYIFNLFIPQSAHSPSKKSQDQLQGLCSLAAEGIWTDTFVFTEEALRRNGILDSDIPTLLDIGMLGKMGKFENCYIFLHPSLQEACAAIFYLLKSHGDHPIEDVKSVEALLFTFLKKAKVQWILGGRFIFGLLHESEQKKLEAFFGHQLSQEIKHQLYQCLETISVNEELQEQIDGMKLFYCLFEMEDEDFLMEAMNYMEQINFVAKDYSDVIVAAYCLKHCYTLKKLSFSTQNILNEEHEHSCMENLLTCWRHICSVLINSKDIQELQIKDTNLNEPAFSVLYNSLKYCNDTLKVLVENNVFFLCEKYLFFELIQNCNLQHLNLNLTFLSHSDVKLLCDVLNQAECNIEKLEVAACNLSPDDCKMFASILMSSKTLKQLNLSSNILGKGISSLCKSLCHPDCILEHLVLAKCSLSDQCWDYLSDGIRQNKTLNHLDISSNDLKDEGLKVLCRALALPNSVLKSLCLRHCLITTSGCQDLAEVLRNNQNLTSLQISYNKIEDAGVKLLCDAIKQPNCHLEDLGLEACELTGACCEDLASTFTQCRTLWGINLLNNTLDYTGLVVLCEALRQQKCTPHVLGLRITDFDNETQAFLVAEQEKNPDLSILSGV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A1P8-1", "protein_name": "NLR family, pyrin domain containing 4B", "gene_name": "Nlrp4b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASLFSDFGFMWYWKELNKVEFMKFKELLILEILQMGLKQISWTEVKNASREDLAILLVKYCEGKQAWDTTFKVLQKISRHDLTERATGEIAAHANIYRAHLKKKLTRDCSRKFSISIQNFFQDEYDHLENLLIPKVTEEKPQLVFLKGIAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCQDVKQLKTTSLTELISREWPSSSAPIEEILSQPEKLLFIIDSLEGMEWDFTKQESELCDNCLEKQPVNVLLSSLLKKKILPESSLLISATFETFEELKDWIEYTNVRTITGFKESNIKMYFHSLFQDRNRALEAFSFVRENEQLFTLCQAPVICCMVATCLKNEIEKGKDPVSICRRTTSLYTTHIFNLFIPPNVQYPSKKSQDQLQGLCFLAVEGMWTDISVFSEETLRRNGILDSDIPTLLDIGILEQSRESQNSYIFFHPSVQEFCAAMFYLLQTHMNHPSPDVLHVEKLLFSFLKEVNTQWIFLGRFIFGLLNELEHEKLEAFFGYQLSQQLKQELFEWLELLLDPEVKVNTMKFFYCLFEMEEEVFVQSAMNCREEIDVVAKDYYDFIVAAYCLNHGSALRDLSISTQNVLNEKLNQRYMENLLMLWHNICSVFARNKDIHILQMKDTIFNEPVFQILYNYLKNSSCILEVLVANDVSFLCDKYLFFDLIQSYNLELLDLSGTFLSHSDVVILCNILNKAEYKIQELELANCSLSEQSWKYISDVLCQNKTLRHLDISSNDLKDEGLKVLCKALTLPDSVLLTLSVKACFITTVGCQYLAEVLRNNHKLMFLTLSENKLEDSGVKLLCDAIKHPRCQLAQLDLEACELTGACCEDLASTFTQCKTLGWINLVKNALDFNGLVVLCKALKQKTSNLKELRLRITDFDNKSQTFLLSEEKGNKFLNIENDE", "length": 918 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A523-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKMMSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCVPIPRGQMEKADHLDLATLMIDFNGEEKAWGMAVWIFAAINRRDLWEKAKKDQPEWNDACTSNLSMVCQEDSLEEEWIGLLGYLSRISICKKKKDYCKIYRRHVRSRFYSIKDRNARLGESVDLNRRYTQLQLVKEHPSKQEREHELLTIGRTKMWDRPMSSLKLELLFEPEDEHLEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRAPKSLADLIISCWPDPNPPVCKILCKPSRILFLMDGFDELQGAFDEHIEEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEILFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSAYLPGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEEEGVTVRKGPEGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQRQPSQLELFYCLYEMQEEDFVQSAMGHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFLHNSPKEEEEEKRGSQPLDQVQCVFPDPHVACSSRLVNCCLTSSFCRGLFSSLSTNQSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLTHQCCFNISSVLSSSQKLVELDLSDNALGDFGVRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSLCCSALTSVLKTNQNLTHLYLRSNALGDMGLKLLCEGLLHPDCKLQMLELDNCSLTSHSCWDLSTILTHNQSLRKLNLSNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNCETKRTLEALQEEKPELTVVFEISW", "length": 1035 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FA88-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "nlrc11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYCNYNMDNTRSSRDEDIYSCTSRESEEVLSNTSYWSLPSYFRHRKFHRSSVHEKISDSSESSRVSLKSDWSMNPPPLLGEERKSSNLNMSSLVSVRSDWSMDPPPLLRAKGKSAVSSGVSDNIDWLVCSPYLRVERKSSALRHKLSLLKKFQCLYEGTAVQGKPTLLNEIYTELYITESESGEISHEHEVRQIETQSRRSTTEDTAIKCRDIFTPLPGQDKAIRTVLTKGVAGIGKTVSVQKFILDWAEEKENQDVQLIFPLPFREINLIKDKKFSLVSLLQTFFTREIHLDMIQNSAVIFIFDGLDECRLPFNFSRNEILLDVTKETSVDVLLTNLIVGNLLPYALIWITSRPAAADLVPSECVHRVTEVRGFNDPQKEEYFSKRISDQSLANTIISHLKSSRSLYIMCHIPVFCWISATVLEKMLSEAETAEIPKTLTQMYTHFLILQTNIKHQKDYEEKLTDEDMILRLGKLAFQQLMKGNIIFYEEDLRECGIDVAEASVYSGLCTQIFREEFGLYQGKVFSFVHLSIQEHLAALYVHLLFTNHNINVFEQMTKSFEGTPLNKSDLQSLTLNMELFEISEPVLTDVAAMCEMDWRVVNEISALHCKAVDEVLQNKNGHLDLFLRFLLGLSVECNQILLQRLTKQRRHLYNDNKTVEYIKKKIRTINSPEKSISLFHCLNELGDHSLVEEIQQYLTSGKIKEFKLSSSQWSAVAFVLLTSEKKLEEFWLKEFVGAETKADHVLQKLLPVVKESRKAELSKCGLTEECCAALASALRSKLSHVRELDLSGNKLGDSGIENLSTGLENLHCKLEILRLRSCGITAKGCTALASALRSNPEQIRQLDLSENNIRDWGVKHLFTELKNPDCKLEILGLRNCGITIEGCAALTSALIINPSHLRELDISRNSLGDTGQELLTSLLNSQHHKLEILLLHKFPMTFTSLPSSHSPEMFPQRFRTHNLKE", "length": 966 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "E9Q5R7-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "Nlrp12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPSTARDGLYRLSTYLEELEAGELKKFKLFLGIAEDLSQDKIPWGRMEKAGPLEMAQLMVAHMGTREAWLLALSTFQRIHRKDLWERGQGEDLVRVTPNNGLCLFESQSACPLDVSPNAPRKDLQTTYKDYVRRKFQLMEDRNARLGECVNLSNRYTRLLLVKEHSNPIWTQQKFVDVEWERSRTRRHQTSPIQMETLFEPDEERPEPPHTVVLQGAAGMGKSMLAHKVMLDWADGRLFQGRFDYVFYISCRELNRSHTQCSVQDLISSCWPERGISLEDLMQAPDRLLFIIDGFDKLHPSFHDAQGPWCLCWEEKQPTEVLLGSLIRRLLLPQVSLLITTRPCALEKLHGLLEHPRHVEILGFSEEARKEYFYRYFHNTGQASRVLSFLMDYEPLFTMCFVPMVSWVVCTCLKQQLESGELLRQTPRTTTAVYMFYLLSLMQPKPGTPTFKVPANQRGLVSLAAEGLWNQKILFDEQDLGKHGLDGADVSTFLNVNIFQKGIKCEKFYSFIHLSFQEFFAAMYCALNGREAVRRALAEYGFSERNFLALTVHFLFGLLNEEMRCYLERNLGWSISPQVKEEVLAWIQNKAGSEGSTLQHGSLELLSCLYEVQEEDFIQQALSHFQVVVVRSISTKMEHMVCSFCARYCRSTEVLHLHGSAYSTGMEDDPPEPSGVQTQSTYLQERNMLPDVYSAYLSAAVCTNSNLIELALYRNALGSQGVRLLCQGLRHASCKLQNLRLKRCQISGSACQDLAAAVIANRNLIRLDLSDNSIGVPGLELLCEGLQHPRCRLQMIQLRKCLLEAAAGRSLASVLSNNSYLVELDLTGNPLEDSGLKLLCQGLRHPVCRLRTLWLKICHLGQASCEDLASTLKMNQSLLELDLGLNDLGDSGVLLLCEGLSHPDCKLQTLRLGICRLGSVACVGIASVLQVNTCLQELDLSFNDLGDRGLQLLGEGLRHQTCRLQKLWLDNCGLTSKACEDLSSILGISQTLHELYLTNNALGDTGVCLLCKRLRHPGCKLRVLWLFGMDLNKKTHRRMAALRVTKPYLDIGC", "length": 1054 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M918-1", "protein_name": "NLR family, pyrin domain containing 14", "gene_name": "Nlrp14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKTEDEEMEDQLSKEEIVSEDKEFDYRTIIKENFFIIWDKTSLLGESATLNCVTTHKDQKLLEHIFDVNIQTSKSPQTVVLYGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLSGREISQEKEKNFAQLISKHWPSSEGPIEQILCKPSSLLFILDSFDELDFSFEEPEFALCRDWTQKHPVSFLISSLLRKVMLPESYLLVTTRTTAWKRLVPLLQKPHRVKLPGLSRSSRIDYIHHLLKDKTWAMNAVCSIRMNAKLFNMCHVCHVCQMICTFLKEQVEKGGNVEMTCQTSTALFTYYICSLFPRIAGSSVTLPNETLLRSLCQAAVEGIWTMKHVLYQQNLRKHELTREDLSLFLEANVLQQDTECENCYTFTHLQVQEYFAALFYLLRENPEEKDHPLEPFENVHLLLESNHFHDPHLEQMKCFLFGLLNKDRVQQLEETFNLTISRAVREELLVCLEALEKDDSPLSQLRIQDLLHCIYETQDEEFITQALTYFQKIMVKVDEESKLLIYSYCLKHCHSLQTVRLTARADLRNMLDPTAEICLEDAAVRIIHYWQDLFSVLHTNESLLEMDLYESRLDESLMKILNEEFSHPKCNLQKVMFRAVCFLNSCYDFSFLAFNNTVTHLDLKDTDLGDNGVKTLCEALKYQGCKLRVLRLESCDLNVTHCQNLSKALQSNRSLVFLNLSTNSLSNDGVKSLCEVLENPNCPLERLALASCGLTKVGCEVLSSALTKTKRLTHLCLAHNVLEDEGIELLSYTLRHPRCTLQSLVLRCCYFTPIGSEHLSTALQNNKSLIHLDLGFNKLADSGVKLLCQTLQQPNCNLQELELMGCVLTSEACGDLASVLVNNSNLWNLDLGNNILDDAGLNILCEALRNPNCQIRRLGLENCGLTPGCCQDLLDLLSNNQSVIQMNLMKNSLDYEAIRNLCKVLRSPTCKMEFLALDKKDLFKKKIKKFLVDVRINNPHLVIRPQCPNTESGCWWQYF", "length": 990 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0RA38-1", "protein_name": "NLR family pyrin domain containing 2", "gene_name": "Nlrp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEHSDQLGFNLKDVLKKLDKTELNNFKSTLKSCSLPQTMKQISKLTMDLANGAQLAEILTDYCPNDWVKRVTFKILEEINRADLAELVMKQVEEAASKASEEKVSSKPREPLKTSLFPQDFVQGDERPEHKHKKEWRNMYTEKWKKNFWPKCNKEIYVDTESYRTLLTLCNPKIEMPFAYTIVLHGPPGSGKTTMARRLMLEWSESKQAQSFSCAFYISCRKLNNSKPCTFAHLLSMNNPSWRYYMIRRLVLSEQFLFVVDGFDELTFPAGALLRDICGDWNTVKPVEVLLSSLLMRKMEPHSTLLVTTQTQSLHQIYLMVDQPVLVETQGFLEPEKQEYFQQYFEDEEGEEEGEGEGKALRALKEVKCNEALFQMASLPAACGIFCLCLELGMKKGEDLALTCQTYTSMFLNFLCRVFLQEACDGHLNKQLQILFKKICILAADSLLEQVPILCEEDFLKLKLNLNKLHPVVYRCIFLEDSSCTNCLSFICLSIQQLLAAIIFVQELGQESKDVSKYSIQKMLSREARLKNPNLSGVLPFVFSLLNKTHIQELETIFGCQISMGVKRKFLECELGENKPFLLLMDLQEIFSCLYESQEEEFVKEAMALFGEVSLHLKTNMDLVHASFCLKNSQNLQTMFLKVEKAVFPENFATLESTAEDQRFQDKKCMLTLWTDFCDTFHSNEKLAFLEIHESFLNSSSLEILCEKLSSAPCHLQKVVLKNISPDDAYEKLCLIFCGYETISHLTLQGGKLDSMLHSLCKVVKNPACNLKFLSLGSCSTTAQKWDDFFPALKANQSLISLDLTDNNLLDKGVRLLCNTWKQSKCILQRVSLENCHLTEVCCKDLSSVLMVSQTLTHLSLAKNELGDNGVKKLCESLSFPKCKLQTLVLWSCNITSNGCHYLSKMLGQAPSLKHLDLGLNRIGTTGAKFLCEALKSPRSNLKSLWLCGCSIIPTNCKDFSEILRSNKSLNTLDLSQNVMGTDAVKIFCESLKLQICPLQTLRLKFDEANPSIQKLIQEMKESHPQLSITSDQVDPKKKSHSFPHFIF", "length": 1048 }, "evidence": [ { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P59046-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 12", "gene_name": "NLRP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRTAGRDGLCRLSTYLEELEAVELKKFKLYLGTATELGEGKIPWGSMEKAGPLEMAQLLITHFGPEEAWRLALSTFERINRKDLWERGQREDLVRDTPPGGPSSLGNQSTCLLEVSLVTPRKDPQETYRDYVRRKFRLMEDRNARLGECVNLSHRYTRLLLVKEHSNPMQVQQQLLDTGRGHARTVGHQASPIKIETLFEPDEERPEPPRTVVMQGAAGIGKSMLAHKVMLDWADGKLFQGRFDYLFYINCREMNQSATECSMQDLIFSCWPEPSAPLQELIRVPERLLFIIDGFDELKPSFHDPQGPWCLCWEEKRPTELLLNSLIRKKLLPELSLLITTRPTALEKLHRLLEHPRHVEILGFSEAERKEYFYKYFHNAEQAGQVFNYVRDNEPLFTMCFVPLVCWVVCTCLQQQLEGGGLLRQTSRTTTAVYMLYLLSLMQPKPGAPRLQPPPNQRGLCSLAADGLWNQKILFEEQDLRKHGLDGEDVSAFLNMNIFQKDINCERYYSFIHLSFQEFFAAMYYILDEGEGGAGPDQDVTRLLTEYAFSERSFLALTSRFLFGLLNEETRSHLEKSLCWKVSPHIKMDLLQWIQSKAQSDGSTLQQGSLEFFSCLYEIQEEEFIQQALSHFQVIVVSNIASKMEHMVSSFCLKRCRSAQVLHLYGATYSADGEDRARCSAGAHTLLVQLPERTVLLDAYSEHLAAALCTNPNLIELSLYRNALGSRGVKLLCQGLRHPNCKLQNLRLKRCRISSSACEDLSAALIANKNLTRMDLSGNGVGFPGMMLLCEGLRHPQCRLQMIQLRKCQLESGACQEMASVLGTNPHLVELDLTGNALEDLGLRLLCQGLRHPVCRLRTLWLKICRLTAAACDELASTLSVNQSLRELDLSLNELGDLGVLLLCEGLRHPTCKLQTLRLGICRLGSAACEGLSVVLQANHNLRELDLSFNDLGDWGLWLLAEGLQHPACRLQKLWLDSCGLTAKACENLYFTLGINQTLTDLYLTNNALGDTGVRLLCKRLSHPGCKLRVLWLFGMDLNKMTHSRLAALRVTKPYLDIGC", "length": 1061 }, "evidence": [ { "id": "HGNC:22938", "url": "https://alliancegenome.org/gene/HGNC:22938#orthology", "database": "AGR" }, { "id": "RGD:1309415", "url": "https://alliancegenome.org/gene/RGD:1309415#orthology", "database": "AGR" }, { "id": "MGI:2676630", "url": "https://alliancegenome.org/gene/MGI:2676630#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59047-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 5", "gene_name": "NLRP5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVAGGLELGAAALLSASPRALVTLSTGPTCSILPKNPLFPQNLSSQPCIKMEGDKSLTFSSYGLQWCLYELDKEEFQTFKELLKKKSSESTTCSIPQFEIENANVECLALLLHEYYGASLAWATSISIFENMNLRTLSEKARDDMKRHSPEDPEATMTDQGPSKEKVPGISQAVQQDSATAAETKEQEISQAMEQEGATAAETEEQEISQAMEQEGATAAETEEQGHGGDTWDYKSHVMTKFAEEEDVRRSFENTAADWPEMQTLAGAFDSDRWGFRPRTVVLHGKSGIGKSALARRIVLCWAQGGLYQGMFSYVFFLPVREMQRKKESSVTEFISREWPDSQAPVTEIMSRPERLLFIIDGFDDLGSVLNNDTKLCKDWAEKQPPFTLIRSLLRKVLLPESFLIVTVRDVGTEKLKSEVVSPRYLLVRGISGEQRIHLLLERGIGEHQKTQGLRAIMNNRELLDQCQVPAVGSLICVALQLQDVVGESVAPFNQTLTGLHAAFVFHQLTPRGVVRRCLNLEERVVLKRFCRMAVEGVWNRKSVFDGDDLMVQGLGESELRALFHMNILLPDSHCEEYYTFFHLSLQDFCAALYYVLEGLEIEPALCPLYVEKTKRSMELKQAGFHIHSLWMKRFLFGLVSEDVRRPLEVLLGCPVPLGVKQKLLHWVSLLGQQPNATTPGDTLDAFHCLFETQDKEFVRLALNSFQEVWLPINQNLDLIASSFCLQHCPYLRKIRVDVKGIFPRDESAEACPVVPLWMRDKTLIEEQWEDFCSMLGTHPHLRQLDLGSSILTERAMKTLCAKLRHPTCKIQTLMFRNAQITPGVQHLWRIVMANRNLRSLNLGGTHLKEEDVRMACEALKHPKCLLESLRLDCCGLTHACYLKISQILTTSPSLKSLSLAGNKVTDQGVMPLSDALRVSQCALQKLILEDCGITATGCQSLASALVSNRSLTHLCLSNNSLGNEGVNLLCRSMRLPHCSLQRLMLNQCHLDTAGCGFLALALMGNSWLTHLSLSMNPVEDNGVKLLCEVMREPSCHLQDLELVKCHLTAACCESLSCVISRSRHLKSLDLTDNALGDGGVAALCEGLKQKNSVLARLGLKACGLTSDCCEALSLALSCNRHLTSLNLVQNNFSPKGMMKLCSAFACPTSNLQIIGLWKWQYPVQIRKLLEEVQLLKPRVVIDGSWHSFDEDDRYWWKN", "length": 1200 }, "evidence": [ { "id": "HGNC:21269", "url": "https://alliancegenome.org/gene/HGNC:21269#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3TKR3-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4C", "gene_name": "Nlrp4c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKEFLKQEILQLRLKQISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRKDLMERAGREIAGHSKLYQAHLKKKLTHDYARKFNIKVQDFSKQKFTQDDYDRFENFLISKVTAKKPHMVFLQGAAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPKTSAPIEDILSQPEKLLFVIDNLEVMECDMSERESELCDTCTEKQPVRILLSSLLRRKMLPKSSFLISATPETFEKMEGRVECTNVKIVTGFNESNIKMYFRSLFQDKTKTQEIFSLVKENQQLFTVCQVPVLCWMVATCLKKEIEKGRDLVSVCRRTTSLYTTHIFNLFIPQSAQYPSKESQAQLQSLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPTLLDVRILEKSKKSEKSYIFLHPSIQEVCAAIFYLLKSHMDHPSQDVKSIEALIFTFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQVDGMKLFYCLFEMDDEAFLAQAMNCMEQINFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNVLSEGQEHSYTEKLLMCWHHMCSVLISSKDIYILQVKNTNLNETASLVLYSHLMYPSCTLKALVVNNVTFLCDNRLFFELIQNQCLQHLDLNLTFLSHGDVKLLCDVLSQEECNIEKLMVAACNLSPDDCKVFASVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLVNCSLSEQCWDYLSEVLRRNKTLNHLDISSNDLKDEGLKVLCGALSLPDSVLKSLSVRYCLITTSGCQDLAEVLRKNQNLRNLQVSNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASAFTHCKTLWGINLQENALDHSGLIVLFEALKQQQCTLHVLGLRITDFDKETQELLMAEEEKNPHLSILSSV", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X01-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9C", "gene_name": "Nlrp9c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVDSSSYGLLQYFQKLSDEEFQRFKELLQKEQEKFKLKPLSWTKIKNTSKEDLVTQLYTHYPRQVWDMVLNLFLQVNRKDLSTMAQIERRDKQNKYKEFMKNLFQYIWTSETNTYMPDRSYNTIIDRQYKALLDIFDSESDPATAVVLGTRGKGKTVFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSKLPECSETLDDILSNPKRILFVLDGFDYLKFDLELRTNLCNDWRKRLPTQNVLSSLLQKIMLPECSLLLELGESSCSKIIPLLQNPREIIMSGLSEQSIYFYCVSFFKIQLGVEVFKDLKKNEPLFTLCSNPSMLWMICSSLMWGHYSREEVISSSESTSAIHTIFIMSAFKSIFGLGSSKYKRFKLKTLCTLAVEGMWKQVYVFDSEDLRRNKISESDKTVWLKMKFLQIQGNNIMFYHSTLQWYFATLFYFLKQDKDTYHPVIGSLPQLLGEIYAHKQNQWTHAQTFFFGIATKHVITLLKPCFGNISFKTIRQEIIRYLKSLSQPECNEKLVHPKKLFFCLIENQEERFVSQVMNLFEEITVDISDSDDLGAAEYSLLRASKLKNLHLHIQKKVFSEIHDPEYGSLENFKLDQKFSAINWTMLSILFCNLHVLDLGSCHFNKKVIEVLCNSLSPTPNMPLTVFKLQRLLCSFMTNFGDGSLFCTFLQIPQLKYLNLYGTDLSNDVVEMLCSALKCSTCRVEELLLGKCDISSEACGIMATFLINSKVKHLSLVENPLKNKGVMFLCKMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDIGVNLLCEALKYPNCTLKELWLPGCYLTSECCEEISAVLTCNKNLKTLKLGNNNIQDTGVKRLCEALCHPKCKVQCLGLDMCELSNDCCEDLALALITCNTLKSLNLDWNALHHSGLVMLCEALNHKKCKLNMLGLDKSSFSEESQTFLQAVEKKNNNLNVLHFPWVEDELKKRGVRLVWNSKN", "length": 1004 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X03-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9A", "gene_name": "Nlrp9a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMDSSGYGLLQYLQKLSDEEFQRFKEHLRKEPEKFKLKPISWTKIKNTSKEDLVMQLYTHYPGKAWDMVLSLFLQVNREDLSTMAQTERRDKQTKYKEFMKNTFQHIWTMETNTYIPDRSYHEFIEVQYRALQDIFDCESEPVTVVVSGSRGGGKTTFLRKAMLDWASRNLLQNRFQYVFHFSVFSLNNITELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKKLPIQIVLSSLLQKIMLPECSLLLELGNASLSNIIPLLQYPREIIMSGFSEQTIEIYCVSFFNTQTGVEIFKNLKSIKPLFNLCRCPHLCWMICSTIKWQYERREVASRFGRTLGLLYTIFMVSAFKSTYARNPSKQNRARIRTLCTLAVEGMWKQVYVFDSDDLRRNGISESDKKVWLRMKFLQNQGSNIVFYHSTLQWYFAVLFYFLQYKDTRHPVIGNLAQLLGEIYAHKQNQWFHTRILLFGMATEQVNSLLEPCFGCISSKEVRQEIIRYIKSLSQQECNEKLVVHPQNLFFCILDNQEERFVRQLMDRFEEMTVDISDVDDMSATPYCLHRAPKVKNLHLHIQKRVFLEIHDPEYGDLELFKLGQKCSFTTNFGDGLLFCTFLHLPHLKYMNLYGTNLSNDAVERLCSALKFSTCGVEELLLGKCDISSEACGIIAASLINSEVKHLSLVENPLKNKGVMSLCEMLKDPSCVLESLMLSYCCLTFIACGHLYEALLSNEHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCYLTSECCEEISAVLTCNTNLKTLKLGNNNIQDTGVKRLCEALCHPNCEMQCLGLDMCDFTSDCCEDLALVLTTCNTLKSLNLDWNAFDHSGLEMLCKALNHKACNLEVLGLDKSLFSEESQTLLQAVEKKNKNLKVLHFPWLKEELEKRGVRLVWNSKN", "length": 949 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X05-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4F", "gene_name": "Nlrp4f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFISDFGLIWYLRELNKKEFMKFKDFLIQEILELKLKQVSSTKVKKASREDLANLLLKCGENQAWDMTFRILQKINRKDLTERATGAIVGNPNLYRDHLKKKLTHDCPKKFNVRIQDFIKETFIQNDXDAFENLLISKGTERKPHMVFLKGMAGVGKTLMLKNLMLAWSKGLVFQNKFSYAFYFCCQDVKQLKTASLAELISREWPSPSAPIEEILSQPEKLLFIIDSLEGMEWDLTKQESELCDDCMEKQPVSTLLSSLLRRKMLPESSLLLSTTPETFEKMEDRIQCTDVKTATAFDERSMKIYFHRLFQDRKRAQEAFSLVRENKQLFTICQVPLLCWMVATCLKEEIEKGGDPVSLCRRTTSLYTTHIFSLFIPQSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFGKEALRRNGIFDSDIPTLLDIGMLGKIREFENSYIFLHPSVQEVCAAIFYMLKRHVEHPSQDVKNIETVLFMFLKKVKTQWIFLGCFIFGLLQKSEQEKLGVFFGHRLSKNIHHKLYQCLETLSGNAELQEQIDGMRLFSCLFEMEDEAFLVKAMNCMQQINFVAKNYSDFIVAAYCLKHCSTLKKLSFSTENVLNEGDQSYMEELLICWNNMCSVFVRSKDIQELRIKDTNFNEPAIRVLYESLKYPSFTLNKLVANNVSFGDNHVLFELIQNSSLQYLDLSCSFLSHNEVKLLCDILNQAECNIEKLMIAHCKLSPDDCKIFGSILMSSKSLKVLNLASNNLNQGISSLCKALCHPHCTLEYLVPRSNHCIVNFLLKLSCCGITERGCQDLAEVLKNNQNLKYLHVSYNKLKDTGVMLLCDAIKHPNCHLKDLQLEACEITDASNEELCYAFMQCETLQTLNLMGNAFEVSRMVFFPRKSELMLFIFLHLSRLWITDFDNEFQAFLLSVKKKNHFLTIRGSVEADGEKKGGDSDARTMGELSNEI", "length": 959 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X19-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4E", "gene_name": "Nlrp4e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFMKFKELLQQEILQLGLKHISWTEVKKASREDLANLLLKHYEEKKAWDMTFKIFQKMNRQDLMERAGREIAGHSKLYQVHLKKKLTHDYARKFNIKDQDSLKQKFTQDDCDHFENLLISKATGKKPHMVFLQGVAGIGKSLMLTKLMLAWSEGMVFQNKFSYIFYFCCQDVKKMKRASLAELISKEWPNASAPIEEILSQPEKLLFVIDNLEVMECDMSEWESELCDDCMEKQPVNILMSSLLRRKMLPESSFLVSATPETFEKIEDRIECTNVKMMAGFNESSIKVYFYSLFQDRNRTQEIFSLVRENEQLFSVCQVPVLCWMVATCLKKEIEKGRDPVSICRRITSLYTTYIFNLFIPHSAQYPSKKSQDQLQGLCSLAAEGMWTDTFVFAEEALRRNGIMDSDISTLLDVRILEKSKESEKSYIFLHPSIQEVCAAIFHLLKSHVDHPSQDVKSIEALIFTFLKKVKIQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNKELQEQIDGMKLFYCLFEMDDEAFLPQVMNCMEQIKFVAKDYSDVIVAAHCLQHCSTLKKLSLSTQNILSEGQEHSYTEKLLICWHHVCSVLTSSKDIHVLQVKDTNFNERAFLVLYSHLKYPSCILKVLEVNNVTLLCDNRLLFELIQNQRLQLLNLSLTFLSHNDVKLLCDVLNQAECNIEKLMVADCNLSPDDCKVFVSVLISSKMLKHLNLSSNNLDKGISSLSKALCHPDCVLKNLVLAKCSLSEECWHYLSEVLRRNKTLTHLDISFNDLKDEGLKVLCGALTLPDSVLISLSVRYCLITTSGCQDLAEVLRNNQNLRNLQISNNKIEDAGVKLLCDAIKHPNCHLENIGLEACALTGACCEDLASSFTHCKTLLGINLQENALDHSGLVALFEAMKQQQCTVNLRGLRITDFDKETQEFLMAEKEKNPYLSI", "length": 978 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66X22-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9B", "gene_name": "Nlrp9b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSSGYGLLKLLQKLSDEEFQRFKELLREEPEKFKLKPISWTKIENSSKESLVTLLNTHYPGQAWNMMLSLFLQVNREDLSIMAQKKKRHKQTKYKKFMKTTFERIWTLETNTHIPDRNYHLIVEVQYKALQEIFDSESEPVTAIVAGTTGEGKTTFLRKAMLDWASGVLLQNRFQYVFFFSVFSLNNTTELSLAELISSTLPESSETVDDILSDPKRILFILDGFDYLKFDLELRTNLCNDWRKRLPTQIVLSSLLQKIMLPGCSLLLELGQISVPKIRHLLKYPRVITMQGFSERSVEFYCMSFFDNQRGIEVAENLRNNEVLHLCSNPYLCWMFCSCLKWQFDREEEGYFKAKTDAAFFTNFMVSAFKSTYAHSPSKQNRARLKTLCTLAVEGMWKELFVFDSEDLRRNGISESDKAVWLKMQFLQTHGNHTVFYHPTLQSYFAAMFYFLKQDKDICVPVIGSIPQLLGNMYARGQTQWLQLGTFLFGLINEQVAALLQPCFGFIQPIYVRQEIICYFKCLGQQECNEKLERSQTLFSCLRDSQEERFVRQVVDLLEEITVDISSSDVLSVTAYALQKSSKLKKLHLHIQKTVFSEIYCPDHCKTRTSIGKRRNTAEYWKTLCGIFCNLYVLDLDSCQFNKRAIQDLCNSMSPTPTVPLTAFKLQSLSCSFMADFGDGSLFHTLLQLPHLKYLNLYGTYLSMDVTEKLCAALRCSACRVEELLLGKCGISSKACGIIAISLINSKVKHLSLVENPLKNKGVMSLCEMLKDPSCVLQSLMLSYCCLTFIACGHLYEALLSNKHLSLLDLGSNFLEDTGVNLLCEALKDPNCTLKELWLPGCFLTSQCCEEISAVLICNRNLKTLKLGNNNIQDTGVRQLCEALSHPNCNLECLGLDLCEFTSDCCKDLALALTTCKTLNSLNLDWKTLDHSGLVVLCEALNHKRCNLKMLGLDKSAFSEESQTLLQDVEKKNNNLNILHHPWFEAERNKRGTRLVWNSRN", "length": 1003 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6B966-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "Nlrp14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTEDDEMEYEASKEETVSEDKDFDDGIDYRTVIKENIFTMWYKTSLHGEFATLNCVITPKDQNLLQHIFDEDIQTSEAPQTVVLQGAAGIGKTTLLKKAVLEWADGNLYQQFTHVFYLNGKEISQVKEKSFAQLISKHWPSSEGPIEQVLSKPSSLLFIIDSFDELDFSFEEPQFALCKDWTQISPVSFLISSLLRKVMLPESYLLVATRSTAWKRLVPLLQKPQRVKLSGLSKNARMDYIHHLLKDKAWATSAIYSLRMNWRLFHMCHVCHMCQMICAVLKGQVEKGGRVEETCKTSTALFTYYICSLFPRIPVGCVTLPNETLLRSLCKAAVEGIWTMKHVLYQQNLRKHELTREDILLFLDAKVLQQDTEYENCYMFTHLHVQEFFAALFYLLRENLEEQDYPSEPFENLYLLLESNHIHDPHLEQMKCFLFGLLNKDRVRQLEETFNLTISMEVREELLACLEGLEKDDSSLSQLRFQDLLHCIYETQDQEFITQALMYFQKIIVRVDEEPQLRIYSFCLKHCHTLKTMRLTARADLKNMLDTAEMCLEGAAVQVIHYWQDLFSVLHTNESLIEMDLYESRLDESLMKILNEELSHPKCKLQKLIFRAVDFLNGCQDFTFLASNKKVTHLDLKETDLGVNGLKTLCEALKCKGCKLRVLRLASCDLNVARCQKLSNALQTNRSLVFLNLSLNNLSNDGVKSLCEVLENPNSSLERLALASCGLTKAGCKVLSSALTKSKRLTHLCLSDNVLEDEGIKLLSHTLKHPQCTLQSLVLRSCSFTPIGSEHLSTALLHNRSLVHLDLGQNKLADNGVKLLCHSLQQPHCNLQELELMSCVLTSKACGDLASVLVNNSNLWSLDLGHNILDDAGLNILCDALRNPNCHVQRLGLENCGLTPGCCQDLLGILSNNKSVIQMNLMKNALDHESIKNLCKVLRSPTCKMEFLALDKKEILKKKIKKFLVDVRINNPHLVIGPECPNTESGCWWNYF", "length": 993 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7RTR0-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 9", "gene_name": "NLRP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESFFSDFGLLWYLKELRKEEFWKFKELLKQPLEKFELKPIPWAELKKASKEDVAKLLDKHYPGKQAWEVTLNLFLQINRKDLWTKAQEEMRNKLNPYRKHMKETFQLIWEKETCLHVPEHFYKETMKNEYKELNDAYTAAARRHTVVLEGPDGIGKTTLLRKVMLDWAEGNLWKDRFTFVFFLNVCEMNGIAETSLLELLSRDWPESSEKIEDIFSQPERILFIMDGFEQLKFNLQLKADLSDDWRQRQPMPIILSSLLQKKMLPESSLLIALGKLAMQKHYFMLRHPKLIKLLGFSESEKKSYFSYFFGEKSKALKVFNFVRDNGPLFILCHNPFTCWLVCTCVKQRLERGEDLEINSQNTTYLYASFLTTVFKAGSQSFPPKVNRARLKSLCALAAEGIWTYTFVFSHGDLRRNGLSESEGVMWVGMRLLQRRGDCFAFMHLCIQEFCAAMFYLLKRPKDDPNPAIGSITQLVRASVVQPQTLLTQVGIFMFGISTEEIVSMLETSFGFPLSKDLKQEITQCLESLSQCEADREAIAFQELFIGLFETQEKEFVTKVMNFFEEVFIYIGNIEHLVIASFCLKHCQHLTTLRMCVENIFPDDSGCISDYNEKLVYWRELCSMFITNKNFQILDMENTSLDDPSLAILCKALAQPVCKLRKLIFTSVYFGHDSELFKAVLHNPHLKLLSLYGTSLSQSDIRHLCETLKHPMCKIEELILGKCDISSEVCEDIASVLACNSKLKHLSLVENPLRDEGMTLLCEALKHSHCALERLMLMYCCLTSVSCDSISEVLLCSKSLSLLDLGSNALEDNGVASLCAALKHPGCSIRELWLMGCFLTSDSCKDIAAVLICNGKLKTLKLGHNEIGDTGVRQLCAALQHPHCKLECLGLQTCPITRACCDDIAAALIACKTLRSLNLDWIALDADAVVVLCEALSHPDCALQMLGLHKSGFDEETQKILMSVEEKIPHLTISHGPWIDEEYKIRGVLL", "length": 991 }, "evidence": [ { "id": "HGNC:22941", "url": "https://alliancegenome.org/gene/HGNC:22941#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W24-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 14", "gene_name": "NLRP14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADSSSSSFFPDFGLLLYLEELNKEELNTFKLFLKETMEPEHGLTPWNEVKKARREDLANLMKKYYPGEKAWSVSLKIFGKMNLKDLCERAKEEINWSAQTIGPDDAKAGETQEDQEAVLGDGTEYRNRIKEKFCITWDKKSLAGKPEDFHHGIAEKDRKLLEHLFDVDVKTGAQPQIVVLQGAAGVGKTTLVRKAMLDWAEGSLYQQRFKYVFYLNGREINQLKERSFAQLISKDWPSTEGPIEEIMYQPSSLLFIIDSFDELNFAFEEPEFALCEDWTQEHPVSFLMSSLLRKVMLPEASLLVTTRLTTSKRLKQLLKNHHYVELLGMSEDAREEYIYQFFEDKRWAMKVFSSLKSNEMLFSMCQVPLVCWAACTCLKQQMEKGGDVTLTCQTTTALFTCYISSLFTPVDGGSPSLPNQAQLRRLCQVAAKGIWTMTYVFYRENLRRLGLTQSDVSSFMDSNIIQKDAEYENCYVFTHLHVQEFFAAMFYMLKGSWEAGNPSCQPFEDLKSLLQSTSYKDPHLTQMKCFLFGLLNEDRVKQLERTFNCKMSLKIKSKLLQCMEVLGNSDYSPSQLGFLELFHCLYETQDKAFISQAMRCFPKVAINICEKIHLLVSSFCLKHCRCLRTIRLSVTVVFEKKILKTSLPTNTWDGDRITHCWQDLCSVLHTNEHLRELDLYHSNLDKSAMNILHHELRHPNCKLQKLLLKFITFPDGCQDISTSLIHNKNLMHLDLKGSDIGDNGVKSLCEALKHPECKLQTLRLESCNLTVFCCLNISNALIRSQSLIFLNLSTNNLLDDGVQLLCEALRHPKCYLERLSLESCGLTEAGCEYLSLALISNKRLTHLCLADNVLGDGGVKLMSDALQHAQCTLKSLVLRRCHFTSLSSEYLSTSLLHNKSLTHLDLGSNWLQDNGVKLLCDVFRHPSCNLQDLELMGCVLTNACCLDLASVILNNPNLRSLDLGNNDLQDDGVKILCDALRYPNCNIQRLGLEYCGLTSLCCQDLSSALICNKRLIKMNLTQNTLGYEGIVKLYKVLKSPKCKLQVLGLCKEAFDEEAQKLLEAVGVSNPHLIIKPDCNYHNEEDVSWWWCF", "length": 1093 }, "evidence": [ { "id": "HGNC:22939", "url": "https://alliancegenome.org/gene/HGNC:22939#orthology", "database": "AGR" }, { "id": "RGD:1598218", "url": "https://alliancegenome.org/gene/RGD:1598218#orthology", "database": "AGR" }, { "id": "MGI:1924108", "url": "https://alliancegenome.org/gene/MGI:1924108#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q86W25-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 13", "gene_name": "NLRP13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNFSVITCPNGGTNQGLLPYLMALDQYQLEEFKLCLEPQQLMDFWSAPQGHFPRIPWANLRAADPLNLSFLLDEHFPKGQAWKVVLGIFQTMNLTSLCEKVRAEMKENVQTQELQDPTQEDLEMLEAAAGNMQTQGCQDPNQEELDELEEETGNVQAQGCQDPNQEEPEMLEEADHRRKYRENMKAELLETWDNISWPKDHVYIRNTSKDEHEELQRLLDPNRTRAQAQTIVLVGRAGVGKTTLAMQAMLHWANGVLFQQRFSYVFYLSCHKIRYMKETTFAELISLDWPDFDAPIEEFMSQPEKLLFIIDGFEEIIISESRSESLDDGSPCTDWYQELPVTKILHSLLKKELVPLATLLITIKTWFVRDLKASLVNPCFVQITGFTGDDLRVYFMRHFDDSSEVEKILQQLRKNETLFHSCSAPMVCWTVCSCLKQPKVRYYDLQSITQTTTSLYAYFFSNLFSTAEVDLADDSWPGQWRALCSLAIEGLWSMNFTFNKEDTEIEGLEVPFIDSLYEFNILQKINDCGGCTTFTHLSFQEFFAAMSFVLEEPREFPPHSTKPQEMKMLLQHVLLDKEAYWTPVVLFFFGLLNKNIARELEDTLHCKISPRVMEELLKWGEELGKAESASLQFHILRLFHCLHESQEEDFTKKMLGRIFEVDLNILEDEELQASSFCLKHCKRLNKLRLSVSSHILERDLEILETSKFDSRMHAWNSICSTLVTNENLHELDLSNSKLHASSVKGLCLALKNPRCKVQKLTCKSVTPEWVLQDLIIALQGNSKLTHLNFSSNKLGMTVPLILKALRHSACNLKYLCLEKCNLSAASCQDLALFLTSIQHVTRLCLGFNRLQDDGIKLLCAALTHPKCALERLELWFCQLAAPACKHLSDALLQNRSLTHLNLSKNSLRDEGVKFLCEALGRPDGNLQSLNLSGCSFTREGCGELANALSHNHNVKILDLGENDLQDDGVKLLCEALKPHRALHTLGLAKCNLTTACCQHLFSVLSSSKSLVNLNLLGNELDTDGVKMLCKALKKSTCRLQKLG", "length": 1043 }, "evidence": [ { "id": "HGNC:22937", "url": "https://alliancegenome.org/gene/HGNC:22937#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BU40-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4A", "gene_name": "Nlrp4a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASFFSDFGLMWYLEELNKKEFVKFKEFLKQEVLQLGLKQVSWTEVKKASRQDLASLLLKHYEEKPAWDMTFRFFQKINRKDLIERAKREIDGCPKLYRAHMKTKMTHDSSRAFTISIQNFLKEKFTEDDYDCFENLFQSKGTESKPQVVFLSGGAGVGKTLMLKRLMLAWIESPVFLHKFSYIFYFCCREVKQLKTASLAELISREWPGPSAPIEEILSKPEKLLFIIDSLEGMECDLFKWESELCDNCTEKQPVNVLLSSLLRRKMLPESSLLISATPESFEKMENRIEYTHVKIIKGLKERNIKMSFHRLFQDRNRAHEAFSLVRENEQLFTVCQVPVLCWMVATCLKEEIEKGRDPVSICRCTTSLYTTHIFNLFIPQNAHSPSKKSQDQLQGLCSLAAEGMWTDTFVFGEEALRRNGIMDSDIPILLDIGMLINIRESEKSYIFLHPSVQEVCAAIFYLLKSHVDHPSQEVKSIEKLMFAFLKKVKVQWIFFGSFIFGLLHESEQKKLEAFFGHQLSQEIKRQLYQCLETISGNEELQEQIDGMKLFYCLFEMDDDTFLVEAMNCMEQINFVAKDYSDVIVAAHCLKHCFTLKKLSFSTQNVLSGAQEHSYMERLLTAWNHICSVFIISKDIQELRMKDTNLSESAFSVLYNNLKYHNYTLNVLVANNVFFVCEKYLFFELIQNCNLQHLNLSLTILSHSDVKLLCDVLSQAECNIEELVVAACSISSDDCKVFASVLISNKTLKHLNLASNTLDKGIASLCKSLCHPDCILEHLVLANCSLNEKCWDYLSEVLRRNKTLSHLDISSNDLKDEGLKVLCRALTLPDSVLKSLSLRHCLITISGCQDLAEVLRNNQNLVSLQVSNNKLEDTGVKLLCDAIKHPNCHLEDLGLEACELTGACCEDLASTFTQCKTLWAMNLLKNALDYNGLVVLCEALKQQTCATYVLGLQITDFDTETQAFLVAEQEKNPCLRILSSL", "length": 982 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C6J9-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4B", "gene_name": "Nlrp4b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASLFSDFGFIWYWKELNKIEFMYFKELLIHEILQMGLKQISWTEVKEASREDLAILLVKHCDGNQAWDTTFRVFQMIGRNVITNRATGEIAAHSTIYRAHLKEKLTHDCSRKFNISIQNFFQDEYDHLENLLVPNGTENNPKMVVLQGVAGIGKTILLKNLMIVWSEGLVFQNKFSYIFYFCCHDVKQLQTASLADLISREWPSPSAPMEEILSQPEKLLFIIDSLEGMEWNVTQQDSQLCYNCMEKQPVNVLLSSLLRKKILPESSLLISTSCETFKDLKDWIEYTNVRTITGFKENNINMCFHSLFQDRNIAQEAFSLIRENEQLFTVCQAPVVCYMVATCLKNEIESGKDPVSICRRTTSLYTTHILNLFIPHNAQNPSNNSEDLLDNLCFLAVEGMWTDISVFNEEALRRNGIMDSDIPTLLDIGILEQSRESENSYIFLHPSVQEFCAAMFYLLHSEMDHSCQGVYFIETFLFTFLNKIKKQWVFLGCFFFGLLHETEQEKLEAFFGYHLSKELRRQLFLWLELLLDTLHPDVKKINTMKFFYCLFEMEEEVFVQSAMNCREQIDVVVKGYSDFIVAAYCLSHGSALTDFSISAQNVLNEELGQRGKLLILWHQICSVFLRNKDIKTLRIEDTIFNEPVFKIFYSYLKNSSCILKTLVAYNVSFLCDKRLFLELIQSYNLEELYLRGTFLSHSDVEMLCDILNQAECNIRILDLANCSLCEHSWDYLSDVLRQNKSLRYLNISYNNLKDEGLKALCRALTLPNSALHSLSLEACQLTGACCKDLASTFTRYKCLRRINLAKNSLGFSGLFVLCKAMKDQTCTLYELKLRMADFDSDSQEFLLSEMERNKILSIENGV", "length": 863 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R4B8-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "Nlrp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSVRCKLAQYLEDLEDVDLKKFKMHLEDYPPEKGCIPVPRGQMEKADHLDLATLMIDFNGEEKAWAMAVWIFAAINRRDLWEKAKKDQPEWNDTCTSHSSMVCQEDSLEEEWMGLLGYLSRISICKKKKDYCKMYRRHVRSRFYSIKDRNARLGESVDLNSRYTQLQLVKEHPSKQEREHELLTIGRTKMRDSPMSSLKLELLFEPEDGHSEPVHTVVFQGAAGIGKTILARKIMLDWALGKLFKDKFDYLFFIHCREVSLRTPRSLADLIVSCWPDPNPPVCKILRKPSRILFLMDGFDELQGAFDEHIGEVCTDWQKAVRGDILLSSLIRKKLLPKASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSNELQAREAFRLIQENEVLFTMCFIPLVCWIVCTGLKQQMETGKSLAQTSKTTTAVYVFFLSSLLQSRGGIEEHLFSDYLQGLCSLAADGIWNQKILFEECDLRKHGLQKTDVSAFLRMNVFQKEVDCERFYSFSHMTFQEFFAAMYYLLEEEAEGETVRKGPGGCSDLLNRDVKVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQVRLELLKWIEVKAKAKKLQWQPSQLELFYCLYEMQEEDFVQSAMDHFPKIEINLSTRMDHVVSSFCIKNCHRVKTLSLGFFHNSPKEEEEERRGGRPLDQVQCVFPDTHVACSSRLVNCCLTSSFCRGLFSSLSTNRSLTELDLSDNTLGDPGMRVLCEALQHPGCNIQRLWLGRCGLSHQCCFDISSVLSSSQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLQKLWLVSCCLTSACCQDLALVLSSNHSLTRLYIGENALGDSGVQVLCEKMKDPQCNLQKLGLVNSGLTSICCSALTSVLKTNQNFTHLYLRSNALGDTGLRLLCEGLLHPDCKLQMLELDNCSLTSHSCWNLSTILTHNHSLRKLNLGNNDLGDLCVVTLCEVLKQQGCLLQSLQLGEMYLNRETKRALEALQEEKPELTIVFEISW", "length": 1033 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96MN2-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 4", "gene_name": "NLRP4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASFFSDFGLMWYLEELKKEEFRKFKEHLKQMTLQLELKQIPWTEVKKASREELANLLIKHYEEQQAWNITLRIFQKMDRKDLCMKVMRERTGYTKTYQAHAKQKFSRLWSSKSVTEIHLYFEEEVKQEECDHLDRLFAPKEAGKQPRTVIIQGPQGIGKTTLLMKLMMAWSDNKIFRDRFLYTFYFCCRELRELPPTSLADLISREWPDPAAPITEIVSQPERLLFVIDSFEELQGGLNEPDSDLCGDLMEKRPVQVLLSSLLRKKMLPEASLLIAIKPVCPKELRDQVTISEIYQPRGFNESDRLVYFCCFFKDPKRAMEAFNLVRESEQLFSICQIPLLCWILCTSLKQEMQKGKDLALTCQSTTSVYSSFVFNLFTPEGAEGPTPQTQHQLKALCSLAAEGMWTDTFEFCEDDLRRNGVVDADIPALLGTKILLKYGERESSYVFLHVCIQEFCAALFYLLKSHLDHPHPAVRCVQELLVANFEKARRAHWIFLGCFLTGLLNKKEQEKLDAFFGFQLSQEIKQQIHQCLKSLGERGNPQGQVDSLAIFYCLFEMQDPAFVKQAVNLLQEANFHIIDNVDLVVSAYCLKYCSSLRKLCFSVQNVFKKEDEHSSTSDYSLICWHHICSVLTTSGHLRELQVQDSTLSESTFVTWCNQLRHPSCRLQKLGINNVSFSGQSVLLFEVLFYQPDLKYLSFTLTKLSRDDIRSLCDALNYPAGNVKELALVNCHLSPIDCEVLAGLLTNNKKLTYLNVSCNQLDTGVPLLCEALCSPDTVLVYLMLAFCHLSEQCCEYISEMLLRNKSVRYLDLSANVLKDEGLKTLCEALKHPDCCLDSLCLVKCFITAAGCEDLASALISNQNLKILQIGCNEIGDVGVQLLCRALTHTDCRLEILGLEECGLTSTCCKDLASVLTCSKTLQQLNLTLNTLDHTGVVVLCEALRHPECALQVLGLRKTDFDEETQALLTAEEERNPNLTITDDCDTITRVEI", "length": 994 }, "evidence": [ { "id": "HGNC:22943", "url": "https://alliancegenome.org/gene/HGNC:22943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96P20-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 3", "gene_name": "NLRP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLPRGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRRDLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGLLEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLGESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCESPVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILARKMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLIMSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHIGPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVALEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQARAAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSLAQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCSLAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQKEVDCEKFYSFIHMTFQEFFAAMYYLLEEEKEGRTNVPGSRLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQERTSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQLELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVSSFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQCVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLTELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLSHECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGLKHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLYVGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVCCSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHPDCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGNNDLGDLGVMMFCEVLKQQSCLLQNLGLSEMYFNYETKSALETLQEEKPELTVVFEPSW", "length": 1036 }, "evidence": [ { "id": "HGNC:16400", "url": "https://alliancegenome.org/gene/HGNC:16400#orthology", "database": "AGR" }, { "id": "RGD:1308314", "url": "https://alliancegenome.org/gene/RGD:1308314#orthology", "database": "AGR" }, { "id": "MGI:2653833", "url": "https://alliancegenome.org/gene/MGI:2653833#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9NX02-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 2", "gene_name": "NLRP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVSSAQMGFNLQALLEQLSQDELSKFKYLITTFSLAHELQKIPHKEVDKADGKQLVEILTTHCDSYWVEMASLQVFEKMHRMDLSERAKDEVREAALKSFNKRKPLSLGITRKERPPLDVDEMLERFKTEAQAFTETKGNVICLGKEVFKGKKPDKDNRCRYILKTKFREMWKSWPGDSKEVQVMAERYKMLIPFSNPRVLPGPFSYTVVLYGPAGLGKTTLAQKLMLDWAEDNLIHKFKYAFYLSCRELSRLGPCSFAELVFRDWPELQDDIPHILAQARKILFVIDGFDELGAAPGALIEDICGDWEKKKPVPVLLGSLLNRVMLPKAALLVTTRPRALRDLRILAEEPIYIRVEGFLEEDRRAYFLRHFGDEDQAMRAFELMRSNAALFQLGSAPAVCWIVCTTLKLQMEKGEDPVPTCLTRTGLFLRFLCSRFPQGAQLRGALRTLSLLAAQGLWAQTSVLHREDLERLGVQESDLRLFLDGDILRQDRVSKGCYSFIHLSFQQFLTALFYTLEKEEEEDRDGHTWDIGDVQKLLSGVERLRNPDLIQAGYYSFGLANEKRAKELEATFGCRMSPDIKQELLRCDISCKGGHSTVTDLQELLGCLYESQEEELVKEVMAQFKEISLHLNAVDVVPSSFCVKHCRNLQKMSLQVIKENLPENVTASESDAEVERSQDDQHMLPFWTDLCSIFGSNKDLMGLAINDSFLSASLVRILCEQIASDTCHLQRVVFKNISPADAHRNLCLALRGHKTVTYLTLQGNDQDDMFPALCEVLRHPECNLRYLGLVSCSATTQQWADLSLALEVNQSLTCVNLSDNELLDEGAKLLYTTLRHPKCFLQRLSLENCHLTEANCKDLAAVLVVSRELTHLCLAKNPIGNTGVKFLCEGLRYPECKLQTLVLWNCDITSDGCCDLTKLLQEKSSLLCLDLGLNHIGVKGMKFLCEALRKPLCNLRCLWLWGCSIPPFSCEDLCSALSCNQSLVTLDLGQNPLGSSGVKMLFETLTCSSGTLRTLRLKIDDFNDELNKLLEEIEEKNPQLIIDTEKHHPWAERPSSHDFMI", "length": 1062 }, "evidence": [ { "id": "HGNC:22948", "url": "https://alliancegenome.org/gene/HGNC:22948#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-478", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-478#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9R1M5-1", "protein_name": "NACHT, LRR and PYD domains-containing protein 5", "gene_name": "Nlrp5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPPEKESKAILKARGLEEEQKSERKMTSPENDSKSIQKDQGPEQEQTSESTMGPPEKESKAILKARGLEEEQKSERKMTSPENDSKSIQKDQGPEQEQTSESTMGPPEKDSKAILKARGLEEEQKSESTMSPSENVSRAILKDSGSEEVEQASERKMTSPENDSKSIQKDQGPEQEQTSETLQSKEEDEVTEADKDNGGDLQDYKAHVIAKFDTSVDLHYDSPEMKLLSDAFKPYQKTFQPHTIILHGRPGVGKSALARSIVLGWAQGKLFQKMSFVIFFSVREIKWTEKSSLAQLIAKECPDSWDLVTKIMSQPERLLFVIDGLDDMDSVLQHDDMTLSRDWKDEQPIYILMYSLLRKALLPQSFLIITTRNTGLEKLKSMVVSPLYILVEGLSASRRSQLVLENISNESDRIQVFHSLIENHQLFDQCQAPSVCSLVCEALQLQKKLGKRCTLPCQTLTGLYATLVFHQLTLKRPSQSALSQEEQITLVGLCMMAAEGVWTMRSVFYDDDLKNYSLKESEILALFHMNILLQVGHNSEQCYVFSHLSLQDFFAALYYVLEGLEEWNQHFCFIENQRSIMEVKRTDDTRLLGMKRFLFGLMNKDILKTLEVLFEYPVIPTVEQKLQHWVSLIAQQVNGTSPMDTLDAFYCLFESQDEEFVGGALKRFQEVWLLINQKMDLKVSSYCLKHCQNLKAIRVDIRDLLSVDNTLELCPVVTVQETQCKPLLMEWWGNFCSVLGSLRNLKELDLGDSILSQRAMKILCLELRNQSCRIQKLTFKSAEVVSGLKHLWKLLFSNQNLKYLNLGNTPMKDDDMKLACEALKHPKCSVETLRLDSCELTIIGYEMISTLLISTTRLKCLSLAKNRVGVKSMISLGNALSSSMCLLQKLILDNCGLTPASCHLLVSALFSNQNLTHLCLSNNSLGTEGVQQLCQFLRNPECALQRLILNHCNIVDDAYGFLAMRLANNTKLTHLSLTMNPVGDGAMKLLCEALKEPTCYLQELELVDCQLTQNCCEDLACMITTTKHLKSLDLGNNALGDKGVITLCEGLKQSSSSLRRLGLGACKLTSNCCEALSLAISCNPHLNSLNLVKNDFSTSGMLKLCSAFQCPVSNLGIIGLWKQEYYARVRRQLEEVEFVKPHVVIDGDWYASDEDDRNWWKN", "length": 1163 }, "evidence": [ { "id": "HGNC:21269", "url": "https://alliancegenome.org/gene/HGNC:21269#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSD3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PSD3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSD3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1093, "end_pos": 1095, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1106, "end_pos": 1108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 112, "end_pos": 114, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1151, "end_pos": 1153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1222, "end_pos": 1224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1286, "end_pos": 1288, "annotation": "n_glycosylation_sequon" }, { "start_pos": 373, "end_pos": 375, "annotation": "n_glycosylation_sequon" }, { "start_pos": 401, "end_pos": 403, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 668, "end_pos": 670, "annotation": "n_glycosylation_sequon" }, { "start_pos": 737, "end_pos": 739, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" }, { "start_pos": 829, "end_pos": 831, "annotation": "n_glycosylation_sequon" }, { "start_pos": 852, "end_pos": 854, "annotation": "n_glycosylation_sequon" }, { "start_pos": 886, "end_pos": 888, "annotation": "n_glycosylation_sequon" }, { "start_pos": 932, "end_pos": 934, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8M9PSD3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PSD3" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 305, "end_pos": 439, "start_aa": "Arg", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1093, "end_pos": 1095 }, { "start_pos": 1106, "end_pos": 1108 }, { "start_pos": 112, "end_pos": 114 }, { "start_pos": 1151, "end_pos": 1153 }, { "start_pos": 1222, "end_pos": 1224 }, { "start_pos": 1286, "end_pos": 1288 }, { "start_pos": 373, "end_pos": 375 }, { "start_pos": 401, "end_pos": 403 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 668, "end_pos": 670 }, { "start_pos": 737, "end_pos": 739 }, { "start_pos": 76, "end_pos": 78 }, { "start_pos": 829, "end_pos": 831 }, { "start_pos": 852, "end_pos": 854 }, { "start_pos": 886, "end_pos": 888 }, { "start_pos": 932, "end_pos": 934 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UUY2-1", "uniprot_ac": "A0A8N7UUY2", "uniprot_id": "A0A8N7UUY2_DANRE", "mass": { "chemical_mass": 229951.0, "monoisotopic_mass": 229951.0 }, "refseq": { "ac": "XP_690924", "name": "zinc finger protein Rlf isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690924" }, "gene_names": [ { "name": "rlf", "type": "recommended", "evidence": [ { "id": "A0A8N7UUY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2" } ] }, { "name": "rlf", "type": "synonym", "evidence": [ { "id": "XP_690924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690924" } ] } ], "protein_names": [ { "name": "Zinc finger protein Rlf isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UUY2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein Rlf isoform X1", "type": "synonym", "evidence": [ { "id": "XP_690924", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690924" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_690924.7. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_690924", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690924" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUY2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" }, { "database": "UniProtKB", "id": "A0AC58HRN4", "url": "https://www.uniprot.org/uniprotkb/A0AC58HRN4#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUY2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rlf", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050208-257", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-257", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "562452", "url": "https://www.ncbi.nlm.nih.gov/gene/562452", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "PTHR15507", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15507", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15507:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15507:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25420", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25420", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25580", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25580", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26218", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26218", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_690924", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690924", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UUY2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HRN4", "url": "https://www.uniprot.org/uniprotkb/A0AC58HRN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HRN4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HRN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050208-257", "url": "https://zfin.org/ZDB-GENE-050208-257", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MADENAEAELDWGGRHSLLVDEDTFFAMEGLQATLQQHEAELRQQDVSEESSTGYCNNFCEALMHYAGSRNSLEHGLPLLEVYCLSINCFAAARPHLTGDSPSVALVLKRLALSCLELLLSVPQNNIPLEAWLQFHGSVQAAHEAMLQYGSTDLHALRNITGEGGAWNNSVMVSLLTGQPTDPDEVNAYLALEGDDFMEMRIKHLEKVGELEKALILIKACANCSLLSNQSTFRQTFVTQLCQLLPSEEAILEISRIDAKDVLDIICNLDAEGDERTAFILCTTYFTQQLQQDSTYCSWELTLLWSKLQRRIDVSLESFIERCLQFAAIARTIYHLLFLIRVIQTEAMQLGLAVSVELCVKALRLPRQDDIEAKTMVCKAVVCLLPDDLEVIRACQLTEFLLSPSQEAFDILEELYLRPDEKYDEENAIIPNFLRCELLLSLKAHWPIDPEFWDWKTLKRYCIQLLGLEPVDEIEDEAAPGELCNLGVVLNEEAGKEEEDECELDALSSAGEQQTVEESEKGQKDSEDVSKLADKHQRDKFLCQICHKEVAETRFCHHARKHMEDGMWTCPVCLQKFKTKKEFEPHSKKHIQISAKDHFKKKKVKKKVDQTKDFFKEDSSDELEPGQIPLDPSLAMYYQSTHDPVVLEHILEKAASVPEKQVESDYVTFDYINTYFKLQDRDVYQCPATDCSKNFKLFKYLGVHIKNEHDSEDPNLKHYLKMKDCREKCTFCRKTFMTAYHHRLHRWIHYGDDPYMCVVTGCGARFDTTNELLAHKHGHGFRLSYCCELKGCSFSYCDLGQLYHHEAQHFRDAAYTCTSPGCKNFYYSRKEFLQHLATHDITFTEKDFEAQRKAKRKLLLAVVESDSAFGSKVETENCVQKSGSSSSSQTLAKGRSSVSQTCVAVCFDGKKFTCGLKKCGKTYTTARELQKHLRIAHSDTFNEKDQLCKKKVQVKHSTTRNEDLPKSDPDNTVKTSSTEKSSPKKALSPASESVDCETTKSNLDLDAALTNIMLGLGQLNLNSSNTRHSMCNSQSTCTPTLNTRSPAKAAHSKNESRSHVTGSESKKLPNKSESPKTHDNNKDVSDKKQKKESVSEEEQPQSKSLTKPYNCEAKSCHYQSTTSCALMQHYIKVHGYSEKMVKEMEVFQSETLEPFKTPDSSENSVLEDDQSQSEFLVQATVKPYACEAKSCNYQSVTSHALLKHYIKIHGYSEKKVKNMEVFQSQIFKPFKCHLCSKSYRNKKELRRHYIQMHHIKEDIVEQMKCSFKKNVVEKAPVLSSPKKNTEVKPQSSKKADVKTQKQDNALWQQKCPKHDYRLWVRKVVTKNVHVKAEKKKKASSETRSDVKNTTVDVRGSRRLISKGNLSYILTKYNKPFHCVHKNCNAAFNNQNALVGHLQMVHHYNRSQLCFPCEHKGCEKQYSTLSSLTKHYRRDHNFTKKEKERKILPKLPCTSKSIPKRQMASTEEPIPRFKCTYANCNESYHLNSSLLRHTSQFHQNQTPQNSANTSGNNEFKTSYKKHVFYRHCDPSDSLVVRLQSTPKKEESKNGCQTKLIISPPSQSSKDPQNMPLKQSLRCCRNDQKINSSENFEGVEETPEEELDEVLKPQRINLKNRFDLIVYRTHEEALQMCQDRCLPVAFPCMIQNCDSVVVSMHSLNRHYINVHRFKRKQLTENKDKLCFTAEQLEEIIQKKSAVSAIPDLTRIPNGVLKMEYQSEPATPGGPSQPMSLHSIKTDSKEKEGIEFSEEPLPDRSLLIEAEDLLYGSPKSSGNPEKPVSEESLNHKDEPESELTAPPLIRPPPLDLSPPATLRITVDESSFEASGKDSKSINIPSSVSISVPTPTRQPLRRKNELSEPPLPPVPLSPVPMDPVEHSLSPRAFDIAAYKPMGFESSFLKFIKDKDEEIKLEKPWTAVVSNPCLKPDPNRRRDCFRRNCSVKENTESGAPISRSRRFRSSPLRHLISKGECTSIQNLRMILERALGGCGDQAIKQLQFLKPVVVLERPKSFASIFDLLPSETKV", "length": 2021, "header": "tr|A0A8N7UUY2-1|A0A8N7UUY2_DANRE Isoform 1 of Zinc finger protein Rlf isoform X1 OS=Danio rerio OX=7955 GN=rlf PE=3 SV=2 CANONICAL=A0A8N7UUY2-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UUY2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2/entry#A0A8N7UUY2-1", "sequence": { "sequence": "MADENAEAELDWGGRHSLLVDEDTFFAMEGLQATLQQHEAELRQQDVSEESSTGYCNNFCEALMHYAGSRNSLEHGLPLLEVYCLSINCFAAARPHLTGDSPSVALVLKRLALSCLELLLSVPQNNIPLEAWLQFHGSVQAAHEAMLQYGSTDLHALRNITGEGGAWNNSVMVSLLTGQPTDPDEVNAYLALEGDDFMEMRIKHLEKVGELEKALILIKACANCSLLSNQSTFRQTFVTQLCQLLPSEEAILEISRIDAKDVLDIICNLDAEGDERTAFILCTTYFTQQLQQDSTYCSWELTLLWSKLQRRIDVSLESFIERCLQFAAIARTIYHLLFLIRVIQTEAMQLGLAVSVELCVKALRLPRQDDIEAKTMVCKAVVCLLPDDLEVIRACQLTEFLLSPSQEAFDILEELYLRPDEKYDEENAIIPNFLRCELLLSLKAHWPIDPEFWDWKTLKRYCIQLLGLEPVDEIEDEAAPGELCNLGVVLNEEAGKEEEDECELDALSSAGEQQTVEESEKGQKDSEDVSKLADKHQRDKFLCQICHKEVAETRFCHHARKHMEDGMWTCPVCLQKFKTKKEFEPHSKKHIQISAKDHFKKKKVKKKVDQTKDFFKEDSSDELEPGQIPLDPSLAMYYQSTHDPVVLEHILEKAASVPEKQVESDYVTFDYINTYFKLQDRDVYQCPATDCSKNFKLFKYLGVHIKNEHDSEDPNLKHYLKMKDCREKCTFCRKTFMTAYHHRLHRWIHYGDDPYMCVVTGCGARFDTTNELLAHKHGHGFRLSYCCELKGCSFSYCDLGQLYHHEAQHFRDAAYTCTSPGCKNFYYSRKEFLQHLATHDITFTEKDFEAQRKAKRKLLLAVVESDSAFGSKVETENCVQKSGSSSSSQTLAKGRSSVSQTCVAVCFDGKKFTCGLKKCGKTYTTARELQKHLRIAHSDTFNEKDQLCKKKVQVKHSTTRNEDLPKSDPDNTVKTSSTEKSSPKKALSPASESVDCETTKSNLDLDAALTNIMLGLGQLNLNSSNTRHSMCNSQSTCTPTLNTRSPAKAAHSKNESRSHVTGSESKKLPNKSESPKTHDNNKDVSDKKQKKESVSEEEQPQSKSLTKPYNCEAKSCHYQSTTSCALMQHYIKVHGYSEKMVKEMEVFQSETLEPFKTPDSSENSVLEDDQSQSEFLVQATVKPYACEAKSCNYQSVTSHALLKHYIKIHGYSEKKVKNMEVFQSQIFKPFKCHLCSKSYRNKKELRRHYIQMHHIKEDIVEQMKCSFKKNVVEKAPVLSSPKKNTEVKPQSSKKADVKTQKQDNALWQQKCPKHDYRLWVRKVVTKNVHVKAEKKKKASSETRSDVKNTTVDVRGSRRLISKGNLSYILTKYNKPFHCVHKNCNAAFNNQNALVGHLQMVHHYNRSQLCFPCEHKGCEKQYSTLSSLTKHYRRDHNFTKKEKERKILPKLPCTSKSIPKRQMASTEEPIPRFKCTYANCNESYHLNSSLLRHTSQFHQNQTPQNSANTSGNNEFKTSYKKHVFYRHCDPSDSLVVRLQSTPKKEESKNGCQTKLIISPPSQSSKDPQNMPLKQSLRCCRNDQKINSSENFEGVEETPEEELDEVLKPQRINLKNRFDLIVYRTHEEALQMCQDRCLPVAFPCMIQNCDSVVVSMHSLNRHYINVHRFKRKQLTENKDKLCFTAEQLEEIIQKKSAVSAIPDLTRIPNGVLKMEYQSEPATPGGPSQPMSLHSIKTDSKEKEGIEFSEEPLPDRSLLIEAEDLLYGSPKSSGNPEKPVSEESLNHKDEPESELTAPPLIRPPPLDLSPPATLRITVDESSFEASGKDSKSINIPSSVSISVPTPTRQPLRRKNELSEPPLPPVPLSPVPMDPVEHSLSPRAFDIAAYKPMGFESSFLKFIKDKDEEIKLEKPWTAVVSNPCLKPDPNRRRDCFRRNCSVKENTESGAPISRSRRFRSSPLRHLISKGECTSIQNLRMILERALGGCGDQAIKQLQFLKPVVVLERPKSFASIFDLLPSETKV", "length": 2021, "header": "tr|A0A8N7UUY2-1|A0A8N7UUY2_DANRE Isoform 1 of Zinc finger protein Rlf isoform X1 OS=Danio rerio OX=7955 GN=rlf PE=3 SV=2 CANONICAL=A0A8N7UUY2-1" }, "locus": {} }, { "isoform_ac": "A0AC58HRN4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2/entry#A0AC58HRN4-1", "sequence": { "sequence": "MADENAEAELDWGGRHSLLVDEDTFFAMEGLQATLQQHEAELRQQDVSEESSTGYCNNFCEALMHYAGSRNSLEHGLPLLEVYCLSINCFAAARPHLTGDSPSVALVLKRLALSCLELLLSVPQNNIPLEAWLQFHGSVQAAHEAMLQYGSTDLHALRNITGEGGAWNNSVMVSLLTGQPTDPDEVNAYLALEGDDFMEMRIKHLEKSTFRQTFVTQLCQLLPSEEAILEISRIDAKDVLDIICNLDAEGDERTAFILCTTYFTQQLQQDSTYCSWELTLLWSKLQRRIDVSLESFIERCLQFAAIARTIYHLLFLIRVIQTEAMQLGLAVSVELCVKALRLPRQDDIEAKTMVCKAVVCLLPDDLEVIRACQLTEFLLSPSQEAFDILEELYLRPDEKYDEENAIIPNFLRCELLLSLKAHWPIDPEFWDWKTLKRYCIQLLGLEPVDEIEDEAAPGELCNLGVVLNEEAGKEEEDECELDALSSAGEQQTVEESEKGQKDSEDVSKLADKHQRDKFLCQICHKEVAETRFCHHARKHMEDGMWTCPVCLQKFKTKKEFEPHSKKHIQISAKDHFKKKKVKKKVDQTKDFFKEDSSDELEPGQIPLDPSLAMYYQSTHDPVVLEHILEKAASVPEKQVESDYVTFDYINTYFKLQDRDVYQCPATDCSKNFKLFKYLGVHIKNEHDSEDPNLKHYLKMKDCREKCTFCRKTFMTAYHHRLHRWIHYGDDPYMCVVTGCGARFDTTNELLAHKHGHGFRLSYCCELKGCSFSYCDLGQLYHHEAQHFRDAAYTCTSPGCKNFYYSRKEFLQHLATHDITFTEKDFEAQRKAKRKLLLAVVESDSAFGSKVETENCVQKSGSSSSSQTLAKGRSSVSQTCVAVCFDGKKFTCGLKKCGKTYTTARELQKHLRIAHSDTFNEKDQLCKKKVQVKHSTTRNEDLPKSDPDNTVKTSSTEKSSPKKALSPASESVDCETTKSNLDLDAALTNIMLGLGQLNLNSSNTRHSMCNSQSTCTPTLNTRSPAKAAHSKNESRSHVTGSESKKLPNKSESPKTHDNNKDVSDKKQKKESVSEEEQPQSKSLTKPYNCEAKSCHYQSTTSCALMQHYIKVHGYSEKMVKEMEVFQSETLEPFKTPDSSENSVLEDDQSQSEFLVQATVKPYACEAKSCNYQSVTSHALLKHYIKIHGYSEKKVKNMEVFQSQIFKPFKCHLCSKSYRNKKELRRHYIQMHHIKEDIVEQMKCSFKKNVVEKAPVLSSPKKNTEVKPQSSKKADVKTQKQDNALWQQKCPKHDYRLWVRKVVTKNVHVKAEKKKKASSETRSDVKNTTVDVRGSRRLISKGNLSYILTKYNKPFHCVHKNCNAAFNNQNALVGHLQMVHHYNRSQLCFPCEHKGCEKQYSTLSSLTKHYRRDHNFTKKEKERKILPKLPCTSKSIPKRQMASTEEPIPRFKCTYANCNESYHLNSSLLRHTSQFHQNQTPQNSANTSGNNEFKTSYKKHVFYRHCDPSDSLVVRLQSTPKKEESKNGCQTKLIISPPSQSSKDPQNMPLKQSLRCCRNDQKINSSENFEGVEETPEEELDEVLKPQRINLKNRFDLIVYRTHEEALQMCQDRCLPVAFPCMIQNCDSVVVSMHSLNRHYINVHRFKRKQLTENKDKLCFTAEQLEEIIQKKSAVSAIPDLTRIPNGVLKMEYQSEPATPGGPSQPMSLHSIKTDSKEKEGIEFSEEPLPDRSLLIEAEDLLYGSPKSSGNPEKPVSEESLNHKDEPESELTAPPLIRPPPLDLSPPATLRITVDESSFEASGKDSKSINIPSSVSISVPTPTRQPLRRKNELSEPPLPPVPLSPVPMDPVEHSLSPRAFDIAAYKPMGFESSFLKFIKDKDEEIKLEKPWTAVVSNPCLKPDPNRRRDCFRRNCSVKENTESGAPISRSRRFRSSPLRHLISKGECTSIQNLRMILERALGGCGDQAIKQLQFLKPVVVLERPKSFASIFDLLPSETKV", "length": 1998, "header": "tr|A0AC58HRN4-1|A0AC58HRN4_DANRE Computationally mapped isoform of Zinc finger protein Rlf isoform X2 OS=Danio rerio OX=7955 GN=rlf PE=3 SV=1 CANONICAL=A0A8N7UUY2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1720, "start_aa": "Thr", "end_pos": 1720, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1720", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A2A7F4-1", "protein_name": "Rearranged L-myc fusion sequence", "gene_name": "Rlf", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADGKGDATAAAGAGAGAEAPAVAGAEVETESMARGHRPASPASGAPGLRPCLWQLETELREQEVSEVSSLSYCRSFCQTLLQYASNKNASEHIVYLLEVYRLAIQSFASARPFLTTECEDVLLVLGRLVLSCFELLLSVSESELPCEVWVPFLQSLQESHDALLEFGNNNLQILVHVTKEGVWKNPILLKILSQQPVETEEVNKLIAQEGPSFLQMRIKHLLKSNCIPQATALSKLCAESKELAQVSCFQQAYITCLCSMLPSEEAIQEIAKVDCKDVLDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRIDPSLETFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGIGVSILLCVRALQLRSSEDEEMKASVCKTISCLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYLQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYDDGKEDKQYRRSLTDQNKEKRDKKPIGSSERYQRWLQYKFFCLLCKRECIEARILHHSKMHMEDGIYTCPVCIKKFKRKELFVPHVMEHVKMPPSRSHRSRKKLLLKSAQRGIYPKSPTGSLEQNPEQARGESHEYVTFSKLEDRRLQDRDLYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCTYCRRHFMSAFHLREHEQVHCGPQPYMCVSIDCYARFGSVNELLNHKQKHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNVLGCKKFYYSKIEYQNHLSMHNVESPDGELKKSVKLEEPGAGGKQDCVDQSHLLDETEKSHSLEDHHLCPGSASAHIDTTETLKDNSDSNSSDQLSHSSSTSITEELIDTLDHSETMQDLLLSHEKVFVPSSLKDKCSNVAVCFDGTKFTCGFDGCGSTYKNARGMQKHLRKVHPYHCKPRKIKTKDLFNCLDDKHNEADKFDAEPKPSSDTNSDSPDEGPDHSIHTKCKREHQGYSPEPSICASKRPCTEDTMLELLLRLKHLSLKNSIAHGSFSGSLQGCPSSGAKSLQSVPSSISDVNLQNQDENMPSQYLAQLAAKPFFCELQGCKYEFVTREALLMHYLKKHNYSKEKVLQLTMFQHRYSPFRCHICQRSFTRKTHLRIHYKNKHQIGSDRATHRLLDSEKCDHEGPCSVDRLKGDCSTELGPNSNSETTQCHSKKDECSSETDLESSCEETESKISGISSPIGSHREEGEEKEGRGSRRTVAKGNLCYILNKYHKPFHCIHKTCNSSFTNLKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKLFACKYKDCNKRFLCSKALAKHCSDSHNLDHIEESKVLSETESAARFSCNQPQCPAVFYSFSKLKHHLLEQHNIEGEIHSDYEIHCTLNGCGQIFSHRSNYFQHVYYRHKDYYDNLFSSQKVANERLLRSEKVCQTTQAQGLTQTQGQTQGQTQGQEQQAAKRPFNTKAKKCGLLKDKKAPITFKTRAEAIHMCVEHSEHTQYPCMVQGCLSVVKLESSIVRHYKRTHQMNSAYLEQQLENLVVCVKYGTKIKDEPPSEVEPCVKKEESTSCESVHTENGAPGDSSVPLPNTDSTCPAEQDVGQKGCSERNPVFDTHSLLYRGTLKCNHSSETTSLEQCNIAQSSPCKIESPIPNPSGTESGTYFTDFQLPLPRIKEEPGQHSSGQENTVKNATQVPKENIRKHSQPRSFDLKTYKPMGFESSFLKFIQESEEKDDDFDDWEPSEHLTLNNSSHPSNDLTGNVVADTIVNESAPQVDIPHSSSDPPVSENLTAVPPLVVAEATAVPSLENLRVVLDKALTDCGELALKQLHYLRPVVVLERSKFSTPILDLFPTKKTDELCVGSS", "length": 1918 }, "evidence": [ { "id": "HGNC:10025", "url": "https://alliancegenome.org/gene/HGNC:10025#orthology", "database": "AGR" }, { "id": "MGI:1924705", "url": "https://alliancegenome.org/gene/MGI:1924705#orthology", "database": "AGR" }, { "id": "RGD:1305297", "url": "https://alliancegenome.org/gene/RGD:1305297#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-257", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-257#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZJX1-1", "protein_name": "RLF zinc finger", "gene_name": "Rlf", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADGKGDATAAAGAGAGAEAAAAAGAGTETESMARGHRPASPASGAPGLRPCLWQLETELREQEVSEVSSLNYCRSFCQTLLQYASNKNASEHIVYLLEVYRLAIQSFASARPFLTTECEDVLLVLGRLVLSCFELLLSVSESELPCEVWVPFLQSLQESHDALLEFGNNNLQILVHVTKEGVWKNPVLLKILSQQPVETEEVNKLIAQEGPSFLQMRIKHLLKSNCIPQATALSKLCAESKELAQVSCFQQAYVTCLCSMLPSEEAIQEIAKVDCKEVLDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRTDPSLETFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGIGVSILLCVRALQLRSSEDEEMKASVCKTISCLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYLQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYDEGKEDKQYRRSLADQNKEKRDKKPIGSSERYQRWLQYKFFCLLCKRECIEARILHHSKMHMEDGVYTCPVCIKKFKRKELFVPHVMEHVKMPPSRSHRSRKKLLLKSSQSGIYPKSPTGSLEQNPSLSEQARGESHEYVTFSKLEDRRLQDRDLYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCTYCRRHFMSAFHLREHEQVHCGPQPYMCVSIDCYARFGSVNELLNHKQKHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNVLGCKKFYYSKIEYQNHLSMHNVENPDGELKKSVKLEEPVAGEKQDCVDQSHLLEQTDKSHSPEDLLFCPGSASAHIDTTETLKDNSDSNSSDQLSPSSSTSITEELIDSLDHSETMQDLLLSDEKVFVPSSLKEKCSNVAVCFDGTKFTCGFDGCGSTYKNARGMQKHLRKVHPYHCKPRKIKTKDLFTCLDDKHNEADKFDAEPKPSSDTNSDSLDEGPDHSIHAKCKREHQGYSPEPSICASKRPCTEDTMLELLLRLKHLSLKNSIAHGSFSGSLQGCPSSGAKSLQSVPSSISDLNLQNQDENMPSQYLAQLAAKPFFCELQGCKYEFVTREALLMHYLKKHNYSKEKVLQLTMFQHRYSPFRCHICQRSFTRKTHLRIHYKNKHQIGSDRATHRLLDSEKCDHEGPCSVDRLTGDCSAELGPNSSSETTQCHSKKDECSSETDLESSCEETESKMCGISSPTGSHREEGEGKEGRGSRRTVAKGNLCYILNKYHKPFHCIHKTCNSSFTNLKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKLFACKYKDCNKRFLCSKALAKHCSDSHNLDHIEESKVLSETESAARFSCNQPQCPAVFYSFSKLKHHLLEQHNIEGEIHSDYEIHCTLNGCGQIFSHRSNYFQHVYYRHKDYYDNLFSSQKVANERLLRSEKVCQTTQAQGLTQGQGQTQTQGQEQQAAKRPFNTKAKKCGLLKDKKAPISFKTRAEAIHMCVEHSEHTQYPCMVQGCLSVVKLESSIVRHYKRTHQMNSAYLEQQLENLVVCVKYGTKIKDEPPSEVEPCVKKEENASCESVRTESQSPGDSSVPLPNTDSTCPAEQDGGQKGCSERNPVFDTHSLLYRGTLKCNHSSETTSLEQCNIVQSPPCKIESPVANPSGTESGTYFTDFQLPLPRIKEEPGQHSSGQENTVKNATQVPKENIRKHSQPRSFDLKTYKPMGFESSFLKFIQESEEKDDDFDDWEPSEHLTLNNSSQPGNDLTGNVVADTIVNDSDPQVDIPHSSSDPAVPENLTAIPPLVVAEATAVPSLENLRVVLDKALTDCGELALKQLHYLRPVVVLERSKFSTPILDLFPTKKTDELCVGSS", "length": 1919 }, "evidence": [ { "id": "HGNC:10025", "url": "https://alliancegenome.org/gene/HGNC:10025#orthology", "database": "AGR" }, { "id": "MGI:1924705", "url": "https://alliancegenome.org/gene/MGI:1924705#orthology", "database": "AGR" }, { "id": "RGD:1305297", "url": "https://alliancegenome.org/gene/RGD:1305297#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-257", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-257#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13129-1", "protein_name": "Zinc finger protein Rlf", "gene_name": "RLF", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADGKGDAAAVAGAGAEAPAVAGAGDGVETESMVRGHRPVSPAPGASGLRPCLWQLETELREQEVSEVSSLNYCRSFCQTLLQYASNKNASEHIVYLLEVYRLAIQSFASARPYLTTECEDVLLVLGRLVLSCFELLLSVSESELPCEVWLPFLQSLQESHDALLEFGNNNLQILVHVTKEGVWKNPVLLKILSQQPVETEEVNKLIAQEGPSFLQMRIKHLLKSNCIPQATALSKLCAESKEISNVSSFQQAYITCLCSMLPNEDAIKEIAKVDCKEVLDIICNLESEGQDNTAFVLCTTYLTQQLQTASVYCSWELTLFWSKLQRRIDPSLDTFLERCRQFGVIAKTQQHLFCLIRVIQTEAQDAGLGVSILLCVRALQLRSSEDEEMKASVCKTIACLLPEDLEVRRACQLTEFLIEPSLDGFNMLEELYLQPDQKFDEENAPVPNSLRCELLLALKAHWPFDPEFWDWKTLKRHCHQLLGQEASDSDDDLSGYEMSINDTDVLESFLSDYDEGKEDKQYRRRDLTDQHKEKRDKKPIGSSERYQRWLQYKFFCLLCKRECIEARILHHSKMHMEDGIYTCPVCIKKFKRKEMFVPHVMEHVKMPPSRRDRSKKKLLLKGSQKGICPKSPSAIPEQNHSLNDQAKGESHEYVTFSKLEDCHLQDRDLYPCPGTDCSRVFKQFKYLSVHLKAEHQNNDENAKHYLDMKNRREKCTYCRRHFMSAFHLREHEQVHCGPQPYMCVSIDCYARFGSVNELLNHKQKHDDLRYKCELNGCNIVFSDLGQLYHHEAQHFRDASYTCNFLGCKKFYYSKIEYQNHLSMHNVENSNGDIKKSVKLEESATGEKQDCINQPHLLNQTDKSHLPEDLFCAESANSQIDTETAENLKENSDSNSSDQLSHSSSASMNEELIDTLDHSETMQDVLLSNEKVFGPSSLKEKCSSMAVCFDGTKFTCGFDGCGSTYKNARGMQKHLRKVHPYHFKPKKIKTKDLFPSLGNEHNQTTEKLDAEPKPCSDTNSDSPDEGLDHNIHIKCKREHQGYSSESSICASKRPCTEDTMLELLLRLKHLSLKNSITHGSFSGSLQGYPSSGAKSLQSVSSISDLNFQNQDENMPSQYLAQLAAKPFFCELQGCKYEFVTREALLMHYLKKHNYSKEKVLQLTMFQHRYSPFQCHICQRSFTRKTHLRIHYKNKHQIGSDRATHKLLDNEKCDHEGPCSVDRLKGDCSAELGGDPSSNSEKPHCHPKKDECSSETDLESSCEETESKTSDISSPIGSHREEQEGREGRGSRRTVAKGNLCYILNKYHKPFHCIHKTCNSSFTNLKGLIRHYRTVHQYNKEQLCLEKDKARTKRELVKCKKIFACKYKECNKRFLCSKALAKHCSDSHNLDHIEEPKVLSEAGSAARFSCNQPQCPAVFYTFNKLKHHLMEQHNIEGEIHSDYEIHCDLNGCGQIFTHRSNYSQHVYYRHKDYYDDLFRSQKVANERLLRSEKVCQTADTQGHEHQTTRRSFNAKSKKCGLIKEKKAPISFKTRAEALHMCVEHSEHTQYPCMVQGCLSVVKLESSIVRHYKRTHQMSSAYLEQQMENLVVCVKYGTKIKEEPPSEADPCIKKEENRSCESERTEHSHSPGDSSAPIQNTDCCHSSERDGGQKGCIESSSVFDADTLLYRGTLKCNHSSKTTSLEQCNIVQPPPPCKIENSIPNPNGTESGTYFTSFQLPLPRIKESETRQHSSGQENTVKNPTHVPKENFRKHSQPRSFDLKTYKPMGFESSFLKFIQESEEKEDDFDDWEPSEHLTLSNSSQSSNDLTGNVVANNMVNDSEPEVDIPHSSSDSTIHENLTAIPPLIVAETTTVPSLENLRVVLDKALTDCGELALKQLHYLRPVVVLERSKFSTPILDLFPTKKTDELCVGSS", "length": 1914 }, "evidence": [ { "id": "HGNC:10025", "url": "https://alliancegenome.org/gene/HGNC:10025#orthology", "database": "AGR" }, { "id": "MGI:1924705", "url": "https://alliancegenome.org/gene/MGI:1924705#orthology", "database": "AGR" }, { "id": "RGD:1305297", "url": "https://alliancegenome.org/gene/RGD:1305297#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-257", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-257#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUY2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUY2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUY2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUY2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1054, "end_pos": 1056, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1070, "end_pos": 1072, "annotation": 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"https://www.uniprot.org/uniprotkb/A0A8N7UW02" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-284e13.4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW02", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-161", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-161", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UW02", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UW02", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd01204", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01204", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "566919", "url": "https://www.ncbi.nlm.nih.gov/gene/566919", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566919", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566919", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UW02", "url": "https://www.orthodb.org/?gene=A0A8N7UW02", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10614:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10614:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02174", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02174", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_695297", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695297", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UW02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW02", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UW02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW02-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-161", "url": "https://zfin.org/ZDB-GENE-060526-161", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MESQAAMEQQSYEDVRKSGYLRKQKSMHRRFFVLRAASEQGPARLEYYENEKKFRSKSPVPKKAVNLDSCFNINKRADSKNKHMIVLYTRGESFAIAADTEEVQNEWYQAMLDLQCKCKTPDECGSGGDCGLPSPGPAFKEVWQVKVWPKGLGQARNLIGIYRLCLTDKTVNFVKLNSDVAAVVLQLMNVRRCGHSENFFFIEVGRSAMTGPGEFWMQVEDSVVAQNMHETLLEAMKALSEEFRQRSKSQTVGVSCGGGTASNPISVPSRRHHPNLPPSQVGFSRRARTETPGVHNTNTSPTPRHGFSRSRTASIGARTEDGGGRATALSTSPSLNGSSCSTTPTLRPKPTRAPTPAKITLSLARYTPNPAPSPAPSLSSSSGHGSECGLGGATFGAVPICTYARIPQRVSMSGSPSDYGSSDEYGSSPGEHSLLAAGLPAALVEGGASYILMGHREGSHKRVHGRRVLRRSSSRECEVERRLLSKRASLPPTSTQGLVPRRREEEEEDEEEYAVMSRSASRESFTSRRGSGGSATTSLVQENSADKGVSTKGGPEDSSIDSGYMSMLPGVTAPPASLSLAVSGSDAVPKGGDEYMAMTPNNSVSPPQHIRLPISEGYMMMSPNSSCSPDLHGISGCIWGSRGSMESRAGSDYMNMSPISARSACSTPPSHPEQQPLQPKMVYSYFSLPRSYKHATLSARFEDNLERVCMGRGEAAGKTGHSAYDCGGDTPVGSGGGGQLSLSSSSFSSSSASSESLEDRSLSLSVGGVGRAARLSTGHRVRGAHPKITSQHHHQQSCGPGVPKQGHLQTRKDKSSSYFVDMSKANTLPRVRETLLPTASQSPGEYVSIVYKGERGGHKGRTAVESGNSRTQGHQRAFHRPQPCQGGSANLPRSFSAPLATSISLSSEYVNMDLGSSPSSLTPLSSFKPAPKVRDEISRVPLVEQEVDMGLRKSKVTGLTPTDVAAAPFTDYTEMKFGLGGDSTSKSPKPGQTPLPSSMEQEHTMNFSSPKAFSNVDQGARVVRAESSARRRHRSETFVAPPTHPLSPSASPSPFPETPHSGLQRQQGLEGNLWSNNQPPSPKCASPGAATLPAAQGSSLTLEQGLNYIDLDLISKENQTSVDGPSGPHSFFSPVVGGLTGGLGGAGGNTTSSINTYASIDFIKSDELRVHQSNRKDSKDC", "length": 1181, "header": "tr|A0A8N7UW02-1|A0A8N7UW02_DANRE Isoform 1 of Insulin receptor substrate 1 OS=Danio rerio OX=7955 GN=si:ch211-284e13.4 PE=4 SV=1 CANONICAL=A0A8N7UW02-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UW02-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW02/entry#A0A8N7UW02-1", "sequence": { "sequence": "MESQAAMEQQSYEDVRKSGYLRKQKSMHRRFFVLRAASEQGPARLEYYENEKKFRSKSPVPKKAVNLDSCFNINKRADSKNKHMIVLYTRGESFAIAADTEEVQNEWYQAMLDLQCKCKTPDECGSGGDCGLPSPGPAFKEVWQVKVWPKGLGQARNLIGIYRLCLTDKTVNFVKLNSDVAAVVLQLMNVRRCGHSENFFFIEVGRSAMTGPGEFWMQVEDSVVAQNMHETLLEAMKALSEEFRQRSKSQTVGVSCGGGTASNPISVPSRRHHPNLPPSQVGFSRRARTETPGVHNTNTSPTPRHGFSRSRTASIGARTEDGGGRATALSTSPSLNGSSCSTTPTLRPKPTRAPTPAKITLSLARYTPNPAPSPAPSLSSSSGHGSECGLGGATFGAVPICTYARIPQRVSMSGSPSDYGSSDEYGSSPGEHSLLAAGLPAALVEGGASYILMGHREGSHKRVHGRRVLRRSSSRECEVERRLLSKRASLPPTSTQGLVPRRREEEEEDEEEYAVMSRSASRESFTSRRGSGGSATTSLVQENSADKGVSTKGGPEDSSIDSGYMSMLPGVTAPPASLSLAVSGSDAVPKGGDEYMAMTPNNSVSPPQHIRLPISEGYMMMSPNSSCSPDLHGISGCIWGSRGSMESRAGSDYMNMSPISARSACSTPPSHPEQQPLQPKMVYSYFSLPRSYKHATLSARFEDNLERVCMGRGEAAGKTGHSAYDCGGDTPVGSGGGGQLSLSSSSFSSSSASSESLEDRSLSLSVGGVGRAARLSTGHRVRGAHPKITSQHHHQQSCGPGVPKQGHLQTRKDKSSSYFVDMSKANTLPRVRETLLPTASQSPGEYVSIVYKGERGGHKGRTAVESGNSRTQGHQRAFHRPQPCQGGSANLPRSFSAPLATSISLSSEYVNMDLGSSPSSLTPLSSFKPAPKVRDEISRVPLVEQEVDMGLRKSKVTGLTPTDVAAAPFTDYTEMKFGLGGDSTSKSPKPGQTPLPSSMEQEHTMNFSSPKAFSNVDQGARVVRAESSARRRHRSETFVAPPTHPLSPSASPSPFPETPHSGLQRQQGLEGNLWSNNQPPSPKCASPGAATLPAAQGSSLTLEQGLNYIDLDLISKENQTSVDGPSGPHSFFSPVVGGLTGGLGGAGGNTTSSINTYASIDFIKSDELRVHQSNRKDSKDC", "length": 1181, "header": "tr|A0A8N7UW02-1|A0A8N7UW02_DANRE Isoform 1 of Insulin receptor substrate 1 OS=Danio rerio OX=7955 GN=si:ch211-284e13.4 PE=4 SV=1 CANONICAL=A0A8N7UW02-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 355, "start_aa": "Thr", "end_pos": 355, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr355", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:566919", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566919", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9QHL3-1", "protein_name": "Insulin receptor substrate 1-B isoform X1", "gene_name": "si:ch73-335l21.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENHMELQNSTEDVRRSGYLRKQKSMHRRYFVLRAASERGPARLEYYESEKKFRGKAPVPKKALALETCFNINKRADSKNKHMIVLYTRAESFVVAAENEADQEEWYQAMVELQCKSKALCENANGGDYGVPSPGPAFKEVWQVKVWPKGLGQAKNLVGIYRLCLTEKTVNFVKLNSDAVAVVLQLMNVRRCGHSENFFFVEVGRSAVTGPGEFWMQVDDSVVAQNMHETLLEAMKALSEEFRQRSKSQSTAAGAGGGTTASNPISVPSRRHHPNPPPSQVGFTRRPRTEPPGSTAGCNNTSPASRHSFPRTRTSSDGAKVDDGGCATTGEIMPCSSPTTNGSVSNTPILRSTSVRASTPVKAQHALMRSTSTPAPSAAPSMPSGSVHGSEFCATGTGTGNSGGGANGSMYSRLPLRQPSVSGSLSDYGSSDEYGSSPGEHSLLTPTMQAGFTASSGSNSLGDEASNYILMSQRGSSKSQTSQNALPQTRRVLRRSSSRECEAERRIMSKRASLPPMALERLAPLRRAGEEAVEEDDYAIMNQTSSRESFVARQDSGPSTSGTGYLEVAAEIKGDGGSSDTGITAVIGGAKGAVDNGYMSMLPGVTAPPVSLSHSLSVTVSDSDSKSADDYMAMTPNNSISPPRQIRPPSGTDGYMMMSPNSSCSPDQRGVPTAWIGSSSADSRTGSDYMNMSPISARSANSTPPPPEPHTPSDQHSNQPQPKMVYSYYSLPRSYKHNTSTHFEEGPGRGKHLVNGGKGIGGGRGLCNSKSKHQEPLVGRHLSLSSSSYSSSSASSESLGEGEEKAIKGTGGAAGVTAKDIERGSLQQRQGSGRAKQGHSGHRGRPLSLFVDVNKANTLPRVRETPLLPEPKSPGEYVSIEFKGERNQKAEGNGTRGFRQDASLPPSSHRHLPRPTSCVAGFLQFSQSSSTPIPPSTASEYVNMELGVSLSPSPISLTPLGFPSFPTPPVTPAAAPKAHDEHRSTVLNDIGAEREMAQRKSRQGSVPQSGDSPTCGDYTKMAFSLNSGSTLSSTSPKSPLLDQPESVVPALGLGLGLDFPLAKVPNPDHGAKVIRADPQGRRRHCSETFQAPSSLLACPSTSSSSAFPDHTQVISRRLGLDGMLWGNSSSSDVSSQYINPGLSSLSVSQTSSMEQGLNYIDLDLANKESSHASTDGQAAVHTPASRIFSSVLGVGGATGGLVGTGGSGSNASNLNMYASIDFYKSEELRTHQGSSSNSRKDGTGETGAH", "length": 1249 }, "evidence": [ { "id": "RGD:69317", "url": "https://alliancegenome.org/gene/RGD:69317#orthology", "database": "AGR" }, { "id": "FB:FBgn0024248", "url": "https://alliancegenome.org/gene/FB:FBgn0024248#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58H7K0-1", "protein_name": "Insulin receptor substrate 2a isoform X1", "gene_name": "irs2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASPPLKGGPSLSNSNNIHSNNIRKHGYLKKQKHGHRRYFVLKDTSDGLPARLEYHENEKKWKNKSAPKRVIFLDSCLSINKRADAKHRYLIALYTKDEYFAVAAENEQEQESWYGDLTDLLSKGKVCDSTVSNSASSLVGFDEGNYGMITPVNAAYKEVWQVNLKAKGLGQSRNITGVFRLCLTSRTISFVKLNSEVASVTLQLMNIRRCGHSDSFFFIEVGRSASTGPGELWMQADDSVVAQNIHETILEAMKAMKELSEFRPRSKSQSSGSNPISVPTRRNLNNLPPSQTGLVRRSRTDSTAATSPVTKFSSCRIRTASEGEGTMIRPVSISVSENGSPMTVGRNHMSRSNTVSVGCRTSEPSLLNHSRSMSMTMYHSPPSVVSPLSLSSISMNGSISNKAHRPSSCSGSVSGSPNDFGFLTCEDYSSSPGDVRYNLANRSDTPSSLSSTPPLRETSELHSYMVMDRPSNFSQNKTSRDMLDVETYRKRTYSLTTPRQQMAHSQLSSASLDEYMLMRAANSHSGRSTNSASPKLSYPEDYGDIEIGSNCNVGDDGYMPMTPGMAPQSAKNDHYMPMSPMSVSAPKQIINPRSHPQSPGSGCTANSPSSGSLEDSGYMKMWSGSKFSLESSDGKAANGEYVNMSPVDTSISPTPPEYFMGPCEPTQRPSPTQSIRFNKQQVPKRVDDNQYVFMSPQNQNQAEEANSVSSLPPLYRPDVMAQRSKVNRPNRLSLDALRMLPRMTEHPLPCEPKSPGEYINIDFAAATQYSSQSMVTVENQASLSSLRQGSPLSDYMNLNQSSHSSKLCEMSSPLDGLPELAECPPDDGTCFLNEQRNLPCPSVSGKGNYTEMSFNSGSLENQKSASVSPTNRVQRLNLGNQGVSKGIGAFLLAASSVDPNGGAKVIRADPQGRRRHSSETFSSTTTVAPVFPSFAHNVKRHSSASVENISVRSSEGSDEEYESPMCQEMSAGYQNGLNYIALNLMEKQETGNCENLVGFKTGGCCKAGINGLHTTPYVCLGFKETATTVQVLLKTIVSICMCGRWLNRCRAVCVCSRAPAALLTAGLLSSMAAA", "length": 1075 }, "evidence": [ { "id": "FB:FBgn0024248", "url": "https://alliancegenome.org/gene/FB:FBgn0024248#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B1WBQ1-1", "protein_name": "Insulin receptor substrate 3", "gene_name": "Irs3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPAGTGPTVSSGGESTDVSLGPPFPWPCPPDVRLCGHLRKQKSQRRRFFVLRADPPRLECYESEKKFLASGCRPPRPRRTVSLEGACTISKRADARQRHLIVIYTSDSSLGVAAASEAEQQTWYSALLEVRATAAAAAATAMGFSPQEAPESWIFAPFQDVWPVTLRSKGLGRAPGLSSGSYRLCLGSGALSLLRKPGSKGSRDSRATPPPVLRLSLLSVRRCGHADSFFFLELGRSAPIGPGELWLQAPDAVVAQSIHETVLAAMKRLGSSAASGKAEAPLGDSPKGASAVPAPAPYEIPALALAAQARSPGERAKQDYVNPLERMGSAPSYRGPDLGGDYIAMGMRNDYVHMGGKAAEYMWMAPPGLPPPTPPRVDPRKEPEDCESTEYMPMNRFLPGPLYYEFKAREPEHGHSSAQCSIRDRWRPTVAQPRSSQGSELSGDYMYIPDYPSARLGSLDSCLNYVDLDLVPPLEVPGAAPGNSPHSYASIKF", "length": 494 }, "evidence": [ { "id": "RGD:69317", "url": "https://alliancegenome.org/gene/RGD:69317#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-161", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-161#orthology", "database": "AGR" }, { "id": "FB:FBgn0024248", "url": "https://alliancegenome.org/gene/FB:FBgn0024248#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MAL5-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "Irs2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASAPLPGPPASAGGDGPNLNNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGTGGEEAAAAGGSPPQPPRLEYYESEKKWKSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDEYFAVAAENEQEQEGWYRALTDLVSEGRSGDGGSGTTGGSCSASLPGALGGSAGAAGCDDNYGLVTPATAVYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCTSCRVRTASEGDGGAAGGAGTAGGRPMSVAGSPLSPGPVRAPLSRSHTLSAGCGGRPSKVALAPAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPLPPGSHPHLPHPLHHPQCQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFSSHRSNTPESIAETPPARDGSGGELYGYMSMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRQVPQPSSASLDEYTLMRATFSGSSGRLCPSLPASSPKVAYNPYPEDYGDIEIGSHKSSSSNLGADDGYMPMTPGAALRSGGPNSCKSDDYMPMSPTSVSAPKQILQPRSAAALPPSGAAVPAPPSGAGRTFPVNGGGYKASSPAESSPEDSGYMRMWCGSKLSMENPDPKLLPNGDYLNMSPSEAGTAGTPPDFFSAALRPGGEALKGVPGHCYSSLPRSYKAPCTCGGGDNDQYVLMSSPVGRILEEERLEPQATPGAGTFGAAGGSHTQPHHSAVPSSMRPSGIVGRPEGFLGQRCRAVRPTRLSLEGLQTLPSMQEYPLPTEPKSPGEYINIDFGEGGTRLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPSTRSGDTVGSIDGLLSPEASSPYPPLPPRPSASPSSLQQPLPPAPGDLYRLPPATAATSQGPTAGSSMSSEPGDNGDYTEMAFGVAATPPQPIAAPPKPEGARVTSPTSGLKRLSLMDQVSGVEAFLQVSQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNSKRHNSASVENVSLRKSSEGNSILGGSDEPSTSPGQAQPSAGVPPAPQARPWNPGQPGALIGCPGGSSSPMRRETSVGFQNGLNYIAIDVRGEQGSLAQSQPQHPQPGDKNSWGRTRSLGGLLGTVGGSGTSGVCGGPGTGALPSASTYASIDFLSHHLKEATVVKE", "length": 1327 }, "evidence": [ { "id": "FB:FBgn0024248", "url": "https://alliancegenome.org/gene/FB:FBgn0024248#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O14654-1", "protein_name": "Insulin receptor substrate 4", "gene_name": "IRS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASCSFTRDQATRRLRGAAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLSTATGSRSDSESEEEDLPVGEEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRHSVRAAAAAAAAAASGAAIPPLIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGAQPDGEPAALAAAAAAEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSARRHLGLVPLEPGGWLRRSRFEQFCHLRAIGDGEDEMLFTRRFVTPSEPVAHSRRGRLHLPRGRRSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPMNNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGGGQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPPPPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPYVPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDSKDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRGLDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSKPSDHEPPKNKAKRPNRLSFITKGYKIKPKPQKPTHEQREADSSSDYVNMDFTKRESNTPAPSTQGLPDSWGIIAEPRQSAFSNYVNVEFGVPFPNPANDLSDLLRAIPRANPLSLDSARWPLPPLPLSATGSNAIEEEGDYIEVIFNSAMTPAMALADSAIRYDAETGRIYVVDPFSECCMDISLSPSRCSEPPPVARLLQEEEQERRRPQSRSQSFFAAARAAVSAFPTDSLERDLSPSSAPAVASAAEPTLALSQVVAAASALAAAPGIGAAAAAAGFDSASARWFQPVANAADAEAVRGAQDVAGGSNPGAHNPSANLARGDNQAGGAAAAAAAPEPPPRSRRVPRPPEREDSDNDDDTHVRMDFARRDNQFDSPKRGR", "length": 1257 }, "evidence": [ { "id": "FB:FBgn0024248", "url": "https://alliancegenome.org/gene/FB:FBgn0024248#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35568-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "IRS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPPESDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKGHHDGAAALGAGGGGGSCSGSSGLGEAGEDLSYGDVPPGPAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSNCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSARLHPPLNHSRSIPMPASRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGPSTLTAPNGHYILSRGGNGHRCTPGTGLGTSPALAGDEAASAADLDNRFRKRTHSAGTSPTITHQKTPSQSSVASIEEYTEMMPAYPPGGGSGGRLPGHRHSAFVPTRSYPEEGLEMHPLERRGGHHRPDSSTLHTDDGYMPMSPGVAPVPSGRKGSGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGGCSPDIGGGPSSSSSSSNAVPSGTSYGKLWTNGVGGHHSHVLPHPKPPVESSGGKLLPCTGDYMNMSPVGDSNTSSPSDCYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSTSSGRLLYAATADDSSSSTSSDSLGGGYCGARLEPSLPHPHHQVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRAREQQQQQQPLLHPPEPKSPGEYVNIEFGSDQSGYLSGPVAFHSSPSVRCPSQLQPAPREEETGTEEYMKMDLGPGRRAAWQESTGVEMGRLGPAPPGAASICRPTRAVPSSRGDYMTMQMSCPRQSYVDTSPAAPVSYADMRTGIAAEEVSLPRATMAAASSSSAASASPTGPQGAAELAAHSSLLGGPQGPGGMSAFTRVNLSPNRNQSAKVIRADPQGCRRRHSSETFSSTPSATRVGNTVPFGAGAAVGGGGGSSSSSEDVKRHSSASFENVWLRPGELGGAPKEPAKLCGAAGGLENGLNYIDLDLVKDFKQCPQECTPEPQPPPPPPPHQPLGSGESSSTRRSSEDLSAYASISFQKQPEDRQ", "length": 1242 }, "evidence": [ { "id": "FB:FBgn0024248", "url": "https://alliancegenome.org/gene/FB:FBgn0024248#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35569-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "Irs1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASPPDTDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKAHHDGAGGGCGGSCSGSSGVGEAGEDLSYDTGPGPAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSDEFRPRSKSQSSSSCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLAAPNGHYILSRGGNGHRYIPGANLGTSPALPGDEAAGAADLDNRFRKRTHSAGTSPTISHQKTPSQSSVASIEEYTEMMPAAYPPGGGSGGRLPGYRHSAFVPTHSYPEEGLEMHHLERRGGHHRPDTSNLHTDDGYMPMSPGVAPVPSNRKGNGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGSCSPDIGGGSSSSSSISAAPSGSSYGKPWTNGVGGHHTHALPHAKPPVESGGGKLLPCTGDYMNMSPVGDSNTSSPSECYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSSSSGRLRYTATAEDSSSSTSSDSLGGGYCGARPESSLTHPHHHVLQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRVREQQQQQQSSLHPPEPKSPGEYVNIEFGSGQPGYLAGPATSRSSPSVRCPPQLHPAPREETGSEEYMNMDLGPGRRATWQESGGVELGRIGPAPPGSATVCRPTRSVPNSRGDYMTMQIGCPRQSYVDTSPVAPVSYADMRTGIAAEKASLPRPTGAAPPPSSTASSSASVTPQGATAEQATHSSLLGGPQGPGGMSAFTRVNLSPNHNQSAKVIRADTQGCRRRHSSETFSAPTRAGNTVPFGAGAAVGGSGGGGGGGSEDVKRHSSASFENVWLRPGDLGGVSKESAPVCGAAGGLEKSLNYIDLDLAKEHSQDCPSQQQSLPPPPPHQPLGSNEGNSPRRSSEDLSNYASISFQKQPEDRQ", "length": 1233 }, "evidence": [ { "id": "FB:FBgn0024248", "url": "https://alliancegenome.org/gene/FB:FBgn0024248#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35570-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "Irs1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPPDTDGFSDVRKVGYLRKPKSMHKRFFVLRAASEAGGPARLEYYENEKKWRHKSSAPKRSIPLESCFNINKRADSKNKHLVALYTRDEHFAIAADSEAEQDSWYQALLQLHNRAKAHHDGAGGGCGGSCSGSSGVGEAGEDLSYDTGPGPAFKEVWQVILKPKGLGQTKNLIGIYRLCLTSKTISFVKLNSEAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMRAMSDEFRPRTKSQSSSSCSNPISVPLRRHHLNNPPPSQVGLTRRSRTESITATSPASMVGGKPGSFRVRASSDGEGTMSRPASVDGSPVSPSTNRTHAHRHRGSSRLHPPLNHSRSIPMPSSRCSPSATSPVSLSSSSTSGHGSTSDCLFPRRSSASVSGSPSDGGFISSDEYGSSPCDFRSSFRSVTPDSLGHTPPARGEEELSNYICMGGKGASTLTAPNGHYILSRGGNGHRYIPGATMGTSPALTGDEAAGAADLDNRFRKRTHSAGTSPTISHQKTPSQSSVVSIEEYTEMMPAAYPPGGGSGGRLPGYRHSAFVPTHSYPEEGLEMHHLERRGGHHRPDSSNLHTDDGYMPMSPGVAPVPSNRKGNGDYMPMSPKSVSAPQQIINPIRRHPQRVDPNGYMMMSPSGSCSPDIGGGSCSSSSISAAPSGSSYGKPWTNGVGGHHTHALPHAKPPVESGGGKLLPCTGDYMNMSPVGDSNTSSPSECYYGPEDPQHKPVLSYYSLPRSFKHTQRPGEPEEGARHQHLRLSSSSGRLRYTATAEDSSSSTSSDSLGGGYCGARPESSVTHPHHHALQPHLPRKVDTAAQTNSRLARPTRLSLGDPKASTLPRVREQQQQQQQQQQSSLHPPEPKSPGEYVNIEFGSGQPGYLAGPATSRSSPSVRCLPQLHPAPREETGSEEYMNMDLGPGRRATWQESGGVELGRVGPAPPGAASICRPTRSVPNSRGDYMTMQIGCPRQSYVDTSPVAPVSYADMRTGIAAEKVSLPRTTGAAPPPSSTASASASVTPQGAAEQAAHSSLLGGPQGPGGMSAFTRVNLSPNHNQSAKVIRADTQGCRRRHSSETFSAPTRAANTVSFGAGAAGGGSGGGSEDVKRHSSASFENVWLRPGDLGGASKESAPGCGAAGGLEKSLNYIDLDLVKDVKQHPQDCPSQQQSLPPPPPHQPLGSNEGSSPRRSSEDLSTYASINFQKQPEDRQ", "length": 1235 }, "evidence": [ { "id": "FB:FBgn0024248", "url": "https://alliancegenome.org/gene/FB:FBgn0024248#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P81122-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "Irs2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASAPLPGPPASAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGTGGDEASAAGGSPPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDEYFAVAAENEQEQEGWYRALTDLVSEGRSGEGGSGTTGGSCSASLPGVLGGSAGAAGCDDNYGLVTPATAVYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCTSCRVRTASEGDGGAAGGAGTAGGRPMSVAGSPLSPGPVRAPLSRSHTLSAGCGGRPSKVTLAPAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPLPPGSHPHLPHPLHHPQGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFSSHRSNTPESIAETPPARDGSGGELYGYMSMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRQVPQPSSASLDEYTLMRATFSGSSGRLCPSFPASSPKVAYNPYPEDYGDIEIGSHKSSSSNLGADDGYMPMTPGAALRSGGPNSCKSDDYMPMSPTSVSAPKQILQPRLAAALPPSGAAVPAPPSGVGRTFPVNGGGYKASSPAESSPEDSGYMRMWCGSKLSMENPDPKLLPNGDYLNMSPSEAGTAGTPPDFSAALRGGSEGLKGIPGHCYSSLPRSYKAPCSCSGDNDQYVLMSSPVGRILEEERLEPQATPGAGTFGAAGGSHTQPHHSAVPSSMRPSAIGGRPEGFLGQRCRAVRPTRLSLEGLQTLPSMQEYPLPTEPKSPGEYINIDFGEAGTRLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPSTRSGDTVGSMDGLLSPEASSPYPPLPPRPSTSPSSLQQPLPPAPGDLYRLPPASAATSQGPTAGSSMSSEPGDNGDYTEMAFGVAATPPQPIVAPPKPEGARVASPTSGLKRLSLMDQVSGVEAFLQVSQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNSKRHNSASVENVSLRKSSEGSSTLGGGDEPPTSPGQAQPLVAVPPVPQARPWNPGQPGALIGCPGGSSSPMRRETSVGFQNGLNYIAIDVRGEQGSLAQSQPQPGDKNSWSRTRSLGGLLGTVGGSGASGVCGGPGTGALPSASTYASIDFLSHHLKEATVVKE", "length": 1321 }, "evidence": [ { "id": "FB:FBgn0024248", "url": "https://alliancegenome.org/gene/FB:FBgn0024248#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9XTN2-1", "protein_name": "Insulin receptor substrate 1", "gene_name": "chico", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASISDDGMALSGYLKKLKTMKKKFFVLYEETSTSAARLEYYDTEKKFLQRAEPKRVIYLKNCFNINRRLDTKHRFVIVLSSRDGGFGIVLENENDLRKWLDKLLVLQRNIANSNGTAHSPYDHVWQVVIQKKGISEKVGITGTYHCCLTSKSLTFVCIGPEKTPNGEDRVASIEILLTTIRRCGHASPQCIFYVELGRQSVLGSGDLWMETDNAAIATNMHNTILSAMSAKTESNTNLINVYQNRPDLSHEPMRKRSSSANEASKPINVNVIQNSQNSLELRSCSSPHNYGFGRERCDSLPTRNGTLSESSNQTYFGSNHGLRSNTISGIRPHSTNKHSNSPTFTMPLRCSESEESSISVDESDDNGSFSHYRLNTRSSETAIPEENIDDFASAELFSKVTEQNVSDENYIPMNPVNPTDAIHEKEKADMQRLEDASLHFNFPEHASEKLAKDFDLDSDNQCCRPIRAYSIGNKVEHLKFNKRLGHLNDTGQNPNRVRAYSVGSKSKIPRCDLQRVVLVEDNKHEFTANRSQSSITKEGTSYGSSANRQKKSTSAPLLSLKNQINSDRMSDLMEIDFSQATNLEKQKFIKNNEIPKYIENVFPKAPRTDSSSLTLHATSQKDIFNGTKLNNTAITSEDGYLEMKPVGNGYTPSSNCLPMKVEKLKLSDYQTAPPLTATAAPVHDLNKISTYNISAEKWREQPSRSEEKKSNSPLNDNTFSSKPTNVESTSKSHDVHSANQIDCEKVCAQSSDKLNNHLADKIVENNNLDIGGHEEKKLVHSISSEDYTQIKDKSNDFTKFNEAGYKILQIKSDSSLISSKLYQKGIHKDNLERSQRLTESVNTIPDNATATAVSSSSLTKFNINSAKPAAAADSRSTGTDPSTPQNILQIKDLNFPSRSSSRISQPELHYASLDLPHCSGQNPAKYLKRGSRESPPVSACPEDGNTYAKIDFDQSDSSSSSSNIFNT", "length": 968 }, "evidence": [ { "id": "RGD:69317", "url": "https://alliancegenome.org/gene/RGD:69317#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-161", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-161#orthology", "database": "AGR" }, { "id": "FB:FBgn0024248", "url": "https://alliancegenome.org/gene/FB:FBgn0024248#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y4H2-1", "protein_name": "Insulin receptor substrate 2", "gene_name": "IRS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASPPRHGPPGPASGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAGGDEATAGGGSAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDEYFAVAAENEQEQEGWYRALTDLVSEGRAAAGDAPPAAAPAASCSASLPGALGGSAGAAGAEDSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQLMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRPRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVRTASEGDGGAAAGAAAAGARPVSVAGSPLSPGPVRAPLSRSHTLSGGCGGRGSKVALLPAGGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPPLPHPLHHGPGQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGGGGGEFYGYMTMDRPLSHCGRSYRRVSGDAAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMRATFSGSAGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGADDGYMPMTPGAALAGSGSGSCRSDDYMPMSPASVSAPKQILQPRAAAAAAAAVPSAGPAGPAPTSAAGRTFPASGGGYKASSPAESSPEDSGYMRMWCGSKLSMEHADGKLLPNGDYLNVSPSDAVTTGTPPDFFSAALHPGGEPLRGVPGCCYSSLPRSYKAPYTCGGDSDQYVLMSSPVGRILEEERLEPQATPGPSQAASAFGAGPTQPPHPVVPSPVRPSGGRPEGFLGQRGRAVRPTRLSLEGLPSLPSMHEYPLPPEPKSPGEYINIDFGEPGARLSPPAPPLLASAASSSSLLSASSPASSLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPGAPSGHPVGSLDGLLSPEASSPYPPLPPRPSASPSSSLQPPPPPPAPGELYRLPPASAVATAQGPGAASSLSSDTGDNGDYTEMAFGVAATPPQPIAAPPKPEAARVASPTSGVKRLSLMEQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGVGVGPGGGDEPPTSPRQLQPAPPLAPQGRPWTPGQPGGLVGCPGSGGSPMRRETSAGFQNGLNYIAIDVREEPGLPPQPQPPPPPLPQPGDKSSWGRTRSLGGLISAVGVGSTGGGCGGPGPGALPPANTYASIDFLSHHLKEATIVKE", "length": 1338 }, "evidence": [ { "id": "FB:FBgn0024248", "url": "https://alliancegenome.org/gene/FB:FBgn0024248#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z0Y7-1", "protein_name": "Insulin receptor substrate 4", "gene_name": "Irs4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASCSFSGHQALRRLRASAAAAASAALAAVATTPLLSSGTRTALIGTGSSCPGAMWLSTATGSRSDSESEEEDLPVGDEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYRNARKFRHSVRAAAAAAEAAASGAAVPALIPPRRVIILYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLGALPDGEPAALAAAAAAEPPFYKDVWQVVVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLLSIRRCGHSEQYFFLEVGRSTVIGPGELWMQVDDSVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAHLLTLLSTRRHLGLLPLEPGGWLRRYGLEQFCRLRAIREREEMLFTRRFISPREPPPPFRRGRGHLPRARRSRRAASVPPSLFRRSAPSPGRIPQPEDVPNDRAREASGSSSGNTEEKDKEGEEGNRGDCIPMNNWGSGNGRGSGGGRGSSGQGSSSQGSGGRQGSGGGQGSGGQGAGGNQCSGNGQGTAGGHGSGGGGHGSGGGQRPGDGHGSGGGKNSGSGKNSDDGDRGKSVKKRSYFGKFTQSKQQQTLPPPPPPPPAAGATGGKGKSGGRFRLYFCADRGTKERKEAKEVRDMETSGGATRGPYRARAFDEDEDDPYVPMRPGVAAPLACSSDYMPMAPQNSSASTKRHSRSPFEDSRGYMMMFPRVSPPPPVPSAPKAPDTNKGDDSKDNDSDSDYMFMAPGAGAIPKNPPNAQGGSSSKSWSSYFSLPSPFQSSPLGQSDHSEYVPMLPGKFLGSGLHKEASFSQGTKNVSSKPSTEASFSKPEDKGSSAKPSDDVPPMNKAKEPNHLSFIAKGTQVKPKPLNPTQERREAAGSRDYINIDFIKRERLVLPSSAQGLPDMRGVVTDPAPTAFSGYLNVEFGVPFPNPTIRLSDLLRVLPGANSIPLAGTRWPFPGSAIGSIVEAGEYIEVIFNPAMTPAMSFADSAICYDAQTGQIYVVDPFSECCMDVSLSPGRCSEPPPVARLRREEAQERRRPQSRSQSLFASTRAAVSAFPTDSLDRDFPAASAVIAAPAEAPLLAVSRALAVVSALAAAPSIGDVFAGFRAAAGVDSASARGFQPVAGAQAVREFQDLAAGWNPGALNHRARGEDLAAGAAAPPPPPRQIWVLRPQERADSEDDDDDDDDIYVRMDFARRDYRK", "length": 1216 }, "evidence": [ { "id": "FB:FBgn0024248", "url": "https://alliancegenome.org/gene/FB:FBgn0024248#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "insulin receptor binding", "id": "GO:0005158", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005158", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW02" } ], "pmid": "" }, { "name": "signaling receptor complex adaptor activity", "id": "GO:0030159", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030159", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW02" } ], "pmid": "" }, { "name": "phosphatidylinositol 3-kinase binding", "id": "GO:0043548", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043548", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW02" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW02" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "insulin receptor signaling pathway", "id": "GO:0008286", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008286", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW02" } ], "pmid": "" }, { "name": "positive regulation of signal transduction", "id": "GO:0009967", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009967", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW02", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW02" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1006, "end_pos": 1008, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1118, "end_pos": 1120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1149, "end_pos": 1151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 655, "end_pos": 657, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UW02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW02" }, { "id": "PS51064", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51064" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IRS-type PTB", "eco_id": "ECO_0000259", "start_pos": 139, "end_pos": 243, "start_aa": "Phe", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UW02", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW02" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 14, "end_pos": 116, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 355 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1006, 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"MCKCKLRSLTWTVFMTVLMIKQQQSVISSSVEVRVNVDKPLRKLEHFWRSTGFCPPQPHTDAHLYDLSPDQQMNLALIGSVPHRGIQQVRIHWMLELVSARVYGGEYHYNFTHLDQLIDLLWQNGLQPGFELMGSVSNTFSNFEDKQQITEWRNLVYLIAKRYIWKYGLGFVSQWNFETWNEPNNHDFDNITVSIQGFLNYYDACSEGLRAASPLLKFGGPGDSCHSQPRSPYCWEMLKHCYNGTNYFTGESGVRLDYIALHKKGGGGSLPILQQEVSTVQEIQQLFPDFCSLPIYNDEADPLVGWNKPLTWRADVTYAAMVLKVISQHQDLLIADRNSTVNYTLLSNDNAFLSYHPHPFSQRTLTARFQINSTNPPHVQILRKPVLTVMGLLALLGETQVQAEVSDVNASVGLLASVHVPQVPFSADSWQSSVLIYNSRDNQTSTSDDVISLRITGLPQRQGLMYVTHYMDNNVTNPFKLWESMSRPDYPTAQQFTQMRNQEDPQTDGPLPVPSDGSLMLKKSLPIPSVLLVHICAQSEEMPNQVNGLRFISITKGQVLIIWKDHCVGTKCIKTYEVEFSRDESTFLRINHRDTIFTYFTYSPESLEVSGFYRARAVDYWGRNGEYSVTEEYSENR", "length": 637, "header": "tr|A2ARH2-1|A2ARH2_DANRE Isoform 1 of Alpha-L-iduronidase isoform X1 OS=Danio rerio OX=7955 GN=idua PE=3 SV=2 CANONICAL=A2ARH2-1" }, "isoforms": [ { "isoform_ac": "A2ARH2-1", "url": "https://www.uniprot.org/uniprotkb/A2ARH2/entry#A2ARH2-1", "sequence": { "sequence": "MCKCKLRSLTWTVFMTVLMIKQQQSVISSSVEVRVNVDKPLRKLEHFWRSTGFCPPQPHTDAHLYDLSPDQQMNLALIGSVPHRGIQQVRIHWMLELVSARVYGGEYHYNFTHLDQLIDLLWQNGLQPGFELMGSVSNTFSNFEDKQQITEWRNLVYLIAKRYIWKYGLGFVSQWNFETWNEPNNHDFDNITVSIQGFLNYYDACSEGLRAASPLLKFGGPGDSCHSQPRSPYCWEMLKHCYNGTNYFTGESGVRLDYIALHKKGGGGSLPILQQEVSTVQEIQQLFPDFCSLPIYNDEADPLVGWNKPLTWRADVTYAAMVLKVISQHQDLLIADRNSTVNYTLLSNDNAFLSYHPHPFSQRTLTARFQINSTNPPHVQILRKPVLTVMGLLALLGETQVQAEVSDVNASVGLLASVHVPQVPFSADSWQSSVLIYNSRDNQTSTSDDVISLRITGLPQRQGLMYVTHYMDNNVTNPFKLWESMSRPDYPTAQQFTQMRNQEDPQTDGPLPVPSDGSLMLKKSLPIPSVLLVHICAQSEEMPNQVNGLRFISITKGQVLIIWKDHCVGTKCIKTYEVEFSRDESTFLRINHRDTIFTYFTYSPESLEVSGFYRARAVDYWGRNGEYSVTEEYSENR", "length": 637, "header": "tr|A2ARH2-1|A2ARH2_DANRE Isoform 1 of Alpha-L-iduronidase isoform X1 OS=Danio rerio OX=7955 GN=idua PE=3 SV=2 CANONICAL=A2ARH2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:567720", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567720", "resource": "KEGG Pathway" }, { "id": "R-DRE-2024096", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-2024096", "resource": "Reactome", "description": "HS-GAG degradation" }, { "id": "R-DRE-2024101", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-2024101", "resource": "Reactome", "description": "CS/DS degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZE16-1", "protein_name": "Alpha-L-iduronidase", "gene_name": "Idua", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGEWSRGALPGGGTLRPLPKSLLFWGRLDIPAMRPPRPASAMLIFFAAFLASPLALAETPYLVRVDAARPLRPLLPFWRSTGFCPPLPHDQADQYDLSWDQQLNLAYIGAVPHSGIEQVRIHWLLDLITARKSSGQGLIYNFTHLDAFLDLLMENQLLPGFELMGSPSGYFTDFEDKQQVFEWKDLVSLLARRYIGKYGLTNVSKWNFETWNEPDHHDFDNVSMTTQGFLNYYDACSEGLRIASPTLRLGGPGDSFHPLPRSPMCWSLLGHCANGTNFFTGEVGVRLDYISLHKKGAGSSIAILEQEVAVVEQIQQLFPKFKDTPIYNDEADPLVGWSLPQPWRADVTYAALVVKVIAQHQNLLFANSSSSMRYILLSNDNAFLSYHPYPFSQRTLTARFQVNNTHPPHVQLLRKPVLTVMGLMALLDGEQLWAEVLKAGAVLDSNHTVGVLASTHHPEGPSEAWRTTVLIYTSDDTHIHPNDSIPVILHLRGVPPGLELVYVVLYLDNQLSSPYSAWQHMGQPVFPSAEQFRQMRMVEDPVAEAPRPFPARGRLTLYRKLPVPSLMLVHLCARPLEPPGQVSRLRALPLTRGQLVLVWSDEHVGSKCLWTYEIQFSQKGEVYAPINRRPSTFNLFVFSPDTAVVSGFYRVRAVDYWARPGPFSDPVTYLDTPAS", "length": 676 }, "evidence": [ { "id": "MGI:96418", "url": "https://alliancegenome.org/gene/MGI:96418#orthology", "database": "AGR" }, { "id": "HGNC:5391", "url": "https://alliancegenome.org/gene/HGNC:5391#orthology", "database": "AGR" }, { "id": "A2ARH2", "url": "https://omabrowser.org/oma/group/A2ARH2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P35475-1", "protein_name": "Alpha-L-iduronidase", "gene_name": "IDUA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPLRPRAALLALLASLLAAPPVAPAEAPHLVHVDAARALWPLRRFWRSTGFCPPLPHSQADQYVLSWDQQLNLAYVGAVPHRGIKQVRTHWLLELVTTRGSTGRGLSYNFTHLDGYLDLLRENQLLPGFELMGSASGHFTDFEDKQQVFEWKDLVSSLARRYIGRYGLAHVSKWNFETWNEPDHHDFDNVSMTMQGFLNYYDACSEGLRAASPALRLGGPGDSFHTPPRSPLSWGLLRHCHDGTNFFTGEAGVRLDYISLHRKGARSSISILEQEKVVAQQIRQLFPKFADTPIYNDEADPLVGWSLPQPWRADVTYAAMVVKVIAQHQNLLLANTTSAFPYALLSNDNAFLSYHPHPFAQRTLTARFQVNNTRPPHVQLLRKPVLTAMGLLALLDEEQLWAEVSQAGTVLDSNHTVGVLASAHRPQGPADAWRAAVLIYASDDTRAHPNRSVAVTLRLRGVPPGPGLVYVTRYLDNGLCSPDGEWRRLGRPVFPTAEQFRRMRAAEDPVAAAPRPLPAGGRLTLRPALRLPSLLLVHVCARPEKPPGQVTRLRALPLTQGQLVLVWSDEHVGSKCLWTYEIQFSQDGKAYTPVSRKPSTFNLFVFSPDTGAVSGSYRVRALDYWARPGPFSDPVPYLEVPVPRGPPSPGNP", "length": 653 }, "evidence": [ { "id": "MGI:96418", "url": "https://alliancegenome.org/gene/MGI:96418#orthology", "database": "AGR" }, { "id": "HGNC:5391", "url": "https://alliancegenome.org/gene/HGNC:5391#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-29", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-29#orthology", "database": "AGR" }, { "id": "A2ARH2", "url": "https://omabrowser.org/oma/group/A2ARH2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P48441-1", "protein_name": "Alpha-L-iduronidase", "gene_name": "Idua", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLTFFAAFLAAPLALAESPYLVRVDAARPLRPLLPFWRSTGFCPPLPHDQADQYDLSWDQQLNLAYIGAVPHSGIEQVRIHWLLDLITARKSPGQGLMYNFTHLDAFLDLLMENQLLPGFELMGSPSGYFTDFDDKQQVFEWKDLVSLLARRYIGRYGLTHVSKWNFETWNEPDHHDFDNVSMTTQGFLNYYDACSEGLRIASPTLKLGGPGDSFHPLPRSPMCWSLLGHCANGTNFFTGEVGVRLDYISLHKKGAGSSIAILEQEMAVVEQVQQLFPEFKDTPIYNDEADPLVGWSLPQPWRADVTYAALVVKVIAQHQNLLFANSSSSMRYVLLSNDNAFLSYHPYPFSQRTLTARFQVNNTHPPHVQLLRKPVLTVMGLMALLDGEQLWAEVSKAGAVLDSNHTVGVLASTHHPEGSAAAWSTTVLIYTSDDTHAHPNHSIPVTLRLRGVPPGLDLVYIVLYLDNQLSSPYSAWQHMGQPVFPSAEQFRRMRMVEDPVAEAPRPFPARGRLTLHRKLPVPSLLLVHVCTRPLKPPGQVSRLRALPLTHGQLILVWSDERVGSKCLWTYEIQFSQKGEEYAPINRRPSTFNLFVFSPDTAVVSGSYRVRALDYWARPGPFSDPVTYLDVPAS", "length": 634 }, "evidence": [ { "id": "MGI:96418", "url": "https://alliancegenome.org/gene/MGI:96418#orthology", "database": "AGR" }, { "id": "HGNC:5391", "url": "https://alliancegenome.org/gene/HGNC:5391#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-29", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-29#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VKJ8-1", "protein_name": "Alpha-L-iduronidase", "gene_name": "Idua", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLSLLLVLTTLARIHAHYTSGDVVYHTMPHFWTGVGFCPAGRIDHEGISAALGDPALRLNLRLIAALPVGAVTHIRIHWLLELIQFWQYDPSGIPIYDFSKFDDFIDFLHEELRLSPVLEWMGNLGGVFSENPMQQSFYWEHLVKTTINHQIARHGSSRLVNWRYETWNEPDLRGYNKQNFTAHTFLDYVQAVRRGLSKAGNLDNQDGKVPLPMYRSLRGPAGLFKDSNHPLCWNLLELCSQRVVYCPIDILTFHRKGIEGTATEIVNGSLSLMAKIYEEYPNLKQLPVANDEADPVAGWSTSRDFQADVRYGITLISTVMQFWHAKLAGGPLSRLESISHDNAFLSYHPHEFTQRTLLAHFRMNETKPPHSQLVQKPVYAALGMLAKLGTRAADVEMVNMDTKHSVQVLRTVSGGLGGPGQYMATIFLSPEEAGPKMTAFHHKYTLNMSIANESAFVTELLVPKETDPYYIWQQAGSPAYPNATLREAMRRAQAPRLYKTGPIWQYNSELVINSASIPLPWAMLLRVCSASWPKLRRPQQLSIAEVTQREVFISWMEHPKSTQCLLSYEVWFKERDNLGRSADWMLISQGWHLPYPSFQYAPGDKGSVNGFYKVRGVDVFNETSPYSQIVEYLEL", "length": 636 }, "evidence": [ { "id": "MGI:96418", "url": "https://alliancegenome.org/gene/MGI:96418#orthology", "database": "AGR" }, { "id": "HGNC:5391", "url": "https://alliancegenome.org/gene/HGNC:5391#orthology", "database": "AGR" }, { "id": "A2ARH2", "url": "https://omabrowser.org/oma/group/A2ARH2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "L-iduronidase activity", "id": "GO:0003940", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003940", "evidence": [ { "database": "UniProtKB", "id": "A2ARH2", "url": "https://www.uniprot.org/uniprotkb/A2ARH2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "carbohydrate metabolic process", "id": "GO:0005975", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005975", "evidence": [ { "database": "UniProtKB", "id": "A2ARH2", "url": "https://www.uniprot.org/uniprotkb/A2ARH2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 110, "end_pos": 112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 243, "end_pos": 245, "annotation": "n_glycosylation_sequon" }, { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A2ARH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2ARH2" }, { "id": "PF21200", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Alpha-L-iduronidase C-terminal", "eco_id": "ECO_0000259", "start_pos": 548, "end_pos": 635, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A2ARH2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2ARH2" }, { "id": "PF01229", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01229" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Glycosyl hydrolases family 39 N-terminal catalytic", "eco_id": "ECO_0000259", "start_pos": 32, "end_pos": 519, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 110, "end_pos": 112 }, { "start_pos": 190, "end_pos": 192 }, { "start_pos": 243, "end_pos": 245 }, { "start_pos": 338, "end_pos": 340 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 409, "end_pos": 411 }, { "start_pos": 442, "end_pos": 444 }, { "start_pos": 474, "end_pos": 476 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A3KQ74-1", "uniprot_ac": "A3KQ74", "uniprot_id": "A3KQ74_DANRE", "mass": { "chemical_mass": 25062.0, "monoisotopic_mass": 25062.0 }, "refseq": { "ac": "NP_001410301", "name": "uncharacterized protein LOC100536640 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410301" }, "gene_names": [ { "name": "si:dkeyp-46h3.8", "type": "recommended", "evidence": [ { "id": "A3KQ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ74" } ] }, { "name": "si:dkeyp-46h3.8", "type": "synonym", "evidence": [ { "id": "NP_001410301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410301" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100536640 precursor", "type": "synonym", "evidence": [ { "id": "A3KQ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ74/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100536640 precursor", "type": "synonym", "evidence": [ { "id": "NP_001410301", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410301" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH446437.1, EH491596.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898399, SAMEA898400 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Jul 18, 2023 this sequence version replaced XP_003200629.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001410301", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410301" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KQ74", "url": "https://www.uniprot.org/uniprotkb/A3KQ74" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkeyp-46h3.8", "url": "https://www.uniprot.org/uniprotkb/A3KQ74", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-183", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-183", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd22836", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22836", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100536640", "url": "https://www.ncbi.nlm.nih.gov/gene/100536640", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100536640", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536640", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A3KQ74", "url": "https://www.orthodb.org/?gene=A3KQ74", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001410301", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410301", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A3KQ74", "url": "https://www.uniprot.org/uniprotkb/A3KQ74", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KQ74-1", "url": "https://www.uniprot.org/uniprotkb/A3KQ74-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-183", "url": "https://zfin.org/ZDB-GENE-060503-183", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFSLRALLNLLMNCSLSAAIALNLPPVDIEVSPLTKSIVICNGDSAVLKCAYGVLQITAANYGRTSKFDCKGRPAFPPNPNCYFNALAPVSQSCNGLQSCEVFATTDTFTDPCPNMRPYLLVTYYCLPPEIRSSAVCENAIANFKCEDGSLIHIHTANYGRTDSSTCAAGRPASQTAKTNCYALNSQTLVANACEGKNSCSISASNGVFSDPCYGTYKYLYTAYSCVPQSYWS", "length": 233, "header": "tr|A3KQ74-1|A3KQ74_DANRE Isoform 1 of Uncharacterized protein LOC100536640 precursor OS=Danio rerio OX=7955 GN=si:dkeyp-46h3.8 PE=4 SV=1 CANONICAL=A3KQ74-1" }, "isoforms": [ { "isoform_ac": "A3KQ74-1", "url": "https://www.uniprot.org/uniprotkb/A3KQ74/entry#A3KQ74-1", "sequence": { "sequence": "MFSLRALLNLLMNCSLSAAIALNLPPVDIEVSPLTKSIVICNGDSAVLKCAYGVLQITAANYGRTSKFDCKGRPAFPPNPNCYFNALAPVSQSCNGLQSCEVFATTDTFTDPCPNMRPYLLVTYYCLPPEIRSSAVCENAIANFKCEDGSLIHIHTANYGRTDSSTCAAGRPASQTAKTNCYALNSQTLVANACEGKNSCSISASNGVFSDPCYGTYKYLYTAYSCVPQSYWS", "length": 233, "header": "tr|A3KQ74-1|A3KQ74_DANRE Isoform 1 of Uncharacterized protein LOC100536640 precursor OS=Danio rerio OX=7955 GN=si:dkeyp-46h3.8 PE=4 SV=1 CANONICAL=A3KQ74-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A3KQ74", "url": "https://www.uniprot.org/uniprotkb/A3KQ74" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100536640", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536640", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A3KQ74", "url": "https://www.uniprot.org/uniprotkb/A3KQ74" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 13, "end_pos": 15, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A3KQ74", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ74" }, { "id": "PS50228", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUEL-type lectin", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 127, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 13, "end_pos": 15 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8N7UQQ7-1", "uniprot_ac": "A0A8N7UQQ7", "uniprot_id": "A0A8N7UQQ7_DANRE", "mass": { "chemical_mass": 146117.0, "monoisotopic_mass": 146117.0 }, "refseq": { "ac": "NP_001353656", "name": "ras-associated and pleckstrin homology domains-containing protein 1a isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353656" }, "gene_names": [ { "name": "raph1a", "type": "recommended", "evidence": [ { "id": "A0A8N7UQQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7" } ] }, { "name": "fj59g11", "type": "synonym", "evidence": [ { "id": "NP_001353656", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353656" } ] }, { "name": "raph1a", "type": "synonym", "evidence": [ { "id": "NP_001353656", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353656" } ] }, { "name": "raph1", "type": "synonym", "evidence": [ { "id": "NP_001353656", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353656" }, { "id": "A0A8N7UQQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7" } ] }, { "name": "si:ch211-176f1.1", "type": "synonym", "evidence": [ { "id": "NP_001353656", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353656" }, { "id": "A0A8N7UQQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7" } ] }, { "name": "wu:fj59g11", "type": "synonym", "evidence": [ { "id": "NP_001353656", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353656" }, { "id": "A0A8N7UQQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7" } ] } ], "protein_names": [ { "name": "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1", "type": "synonym", "evidence": [ { "id": "NP_001353656", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353656" } ] }, { "name": "Ras-associated and pleckstrin homology domains-containing protein 1a isoform 1", "type": "synonym", "evidence": [ { "id": "A0A8N7UQQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7/entry#names_and_taxonomy" } ] }, { "name": "Ras-associated and pleckstrin homology domains-containing protein 1a isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UQQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7/entry#names_and_taxonomy" } ] }, { "name": "ras-associated and pleckstrin homology domains-containing protein 1a isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001353656", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353656" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588724.372092.1, SRR32588733.1457423.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505374, SAMEA3505389 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1. On Oct 18, 2018 this sequence version replaced XP_005167561.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001353656", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353656" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "raph1a", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-8202", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8202", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd01259", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01259", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd16136", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16136", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "557435", "url": "https://www.ncbi.nlm.nih.gov/gene/557435", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039664", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039664", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039665", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039665", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:557435", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557435", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MKMDAIS", "url": "https://omabrowser.org/oma/group/MKMDAIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UQQ7", "url": "https://www.orthodb.org/?gene=A0A8N7UQQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0AC58GE97", "url": "https://www.orthodb.org/?gene=A0AC58GE97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11243", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11243", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11243:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11243:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21989", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21989", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001353656", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001353656", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UQQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UQQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GE81", "url": "https://www.uniprot.org/uniprotkb/A0AC58GE81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GE81-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GE81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GE90", "url": "https://www.uniprot.org/uniprotkb/A0AC58GE90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GE90-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GE90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GE96", "url": "https://www.uniprot.org/uniprotkb/A0AC58GE96", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GE96-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GE96-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GE97", "url": "https://www.uniprot.org/uniprotkb/A0AC58GE97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GE97-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GE97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-156", "url": "https://zfin.org/ZDB-GENE-070912-156", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEQFSDDELDHAAEEDSDKEDQDLDKMFGAWLGELDKLTKSLDDGRPEKVQKAPLRQDSNMANMAYRFSVYNINEALNQGDAVDLDALMADLCSIEQELSTIGKPSSSSSRLGLTGDTKLRQKPPAGRSHSTKHTGGSSSSGGSTSSSTRASPASTVRLSSSSSSSRPPLASNFSLDDITAQLEKASQSMDEAARQGSTPSAAYSSSTVRRPASHHHHHRRTGSVGTVTEHEVRSFVHSSRASINSASASSMDSLDIDKPLSDQDGVQDGQGQPSTEHSYLDRETSLILKSIAGKPSHLLTKEEQAAKQKAEKIRVALEKIKEAQVKKLVVRVHLSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSLDWSLVEIITELQMERIFEDHENLVENLLNWTRDSTNRLMFIERIEKYALFKNPQNYLLGRKETCEMADRNKEALLEECFGGSTISVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLDHVNVYLGQDYRSKYKAPTDYCMVLKHPQIQKKSQYIKYLCCDDVRMLHQWVNGIRIAKYGKQLYVNYQEAMRRTEAAHDWSSLSSSSIKSCSSSSSLPESQSNHSSQSDSGVSETTSSGHVRSQSVVSSIFSEAWKRGNQADEPKMRIDGPPAQPARASYPLQLPPLPQSLQSRSSYSGVSPASPSSPPSPPPPPPPPPPLPNPTHHSTPVVFTKYSTLARLQNISQAPNHYKQTPLLAAQQQPTPPVPPPQCLKPLMNNTTEVASSPPPAPPPPPPPEMPVPGSAMAVLKHAPISPQYTPPPPPEEDPSYLHSNGYLPPPPPPEQLKYPPPLSTNGLQQFLAQKFPNMTYDFSPVQQDEEPPPPPPVCFSPPPQQSGPPAPPKTFTGGFPPQTAPKPGHGISPISPVPPSLSPTPSLMKKQQSLSSGHSPNQPPPTLPKQYSLSSKAPSVSAPISPTQSLVKQIVNQFPDTLDGSKGPISPPVVKNKPKWQPGGQAQPQSPEFPPPPPESTLEFPPPPAPSPPPASQPSGKSGSPIKKSPSTSSNSSTGSGGKKPPPTPQRNSSMKATSSVEYQESKKVEDLVSMFGQTSQAPPSSFSTPSSTTGSPSKESSRALTKPGKINLANLPLALQGRQSHCRQSSADFPSPPLDCEFPPPPPDSELLPPPPLPSELHIGAPKVAVVNPQPQHSSSSTSSWKQSSLKKMPPPTMHRRSSGPPEQLALSPPPQQMPLSSFNSQIPPTSPKANLSMQPNFLEDLNRTLKRKSMTRHGSLTSSRISAKLEPVATMDDMALPPPPPELLLGQQKKGGYTSANISGYATLRRGPPPAPPKRDQNTKLTSEW", "length": 1346, "header": "tr|A0A8N7UQQ7-1|A0A8N7UQQ7_DANRE Isoform 1 of Ras-associated and pleckstrin homology domains-containing protein 1a isoform X1 OS=Danio rerio OX=7955 GN=raph1a PE=1 SV=1 CANONICAL=A0A8N7UQQ7-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UQQ7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7/entry#A0A8N7UQQ7-1", "sequence": { "sequence": "MEQFSDDELDHAAEEDSDKEDQDLDKMFGAWLGELDKLTKSLDDGRPEKVQKAPLRQDSNMANMAYRFSVYNINEALNQGDAVDLDALMADLCSIEQELSTIGKPSSSSSRLGLTGDTKLRQKPPAGRSHSTKHTGGSSSSGGSTSSSTRASPASTVRLSSSSSSSRPPLASNFSLDDITAQLEKASQSMDEAARQGSTPSAAYSSSTVRRPASHHHHHRRTGSVGTVTEHEVRSFVHSSRASINSASASSMDSLDIDKPLSDQDGVQDGQGQPSTEHSYLDRETSLILKSIAGKPSHLLTKEEQAAKQKAEKIRVALEKIKEAQVKKLVVRVHLSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSLDWSLVEIITELQMERIFEDHENLVENLLNWTRDSTNRLMFIERIEKYALFKNPQNYLLGRKETCEMADRNKEALLEECFGGSTISVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLDHVNVYLGQDYRSKYKAPTDYCMVLKHPQIQKKSQYIKYLCCDDVRMLHQWVNGIRIAKYGKQLYVNYQEAMRRTEAAHDWSSLSSSSIKSCSSSSSLPESQSNHSSQSDSGVSETTSSGHVRSQSVVSSIFSEAWKRGNQADEPKMRIDGPPAQPARASYPLQLPPLPQSLQSRSSYSGVSPASPSSPPSPPPPPPPPPPLPNPTHHSTPVVFTKYSTLARLQNISQAPNHYKQTPLLAAQQQPTPPVPPPQCLKPLMNNTTEVASSPPPAPPPPPPPEMPVPGSAMAVLKHAPISPQYTPPPPPEEDPSYLHSNGYLPPPPPPEQLKYPPPLSTNGLQQFLAQKFPNMTYDFSPVQQDEEPPPPPPVCFSPPPQQSGPPAPPKTFTGGFPPQTAPKPGHGISPISPVPPSLSPTPSLMKKQQSLSSGHSPNQPPPTLPKQYSLSSKAPSVSAPISPTQSLVKQIVNQFPDTLDGSKGPISPPVVKNKPKWQPGGQAQPQSPEFPPPPPESTLEFPPPPAPSPPPASQPSGKSGSPIKKSPSTSSNSSTGSGGKKPPPTPQRNSSMKATSSVEYQESKKVEDLVSMFGQTSQAPPSSFSTPSSTTGSPSKESSRALTKPGKINLANLPLALQGRQSHCRQSSADFPSPPLDCEFPPPPPDSELLPPPPLPSELHIGAPKVAVVNPQPQHSSSSTSSWKQSSLKKMPPPTMHRRSSGPPEQLALSPPPQQMPLSSFNSQIPPTSPKANLSMQPNFLEDLNRTLKRKSMTRHGSLTSSRISAKLEPVATMDDMALPPPPPELLLGQQKKGGYTSANISGYATLRRGPPPAPPKRDQNTKLTSEW", "length": 1346, "header": "tr|A0A8N7UQQ7-1|A0A8N7UQQ7_DANRE Isoform 1 of Ras-associated and pleckstrin homology domains-containing protein 1a isoform X1 OS=Danio rerio OX=7955 GN=raph1a PE=1 SV=1 CANONICAL=A0A8N7UQQ7-1" }, "locus": {} }, { "isoform_ac": "A0AC58GE81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7/entry#A0AC58GE81-1", "sequence": { "sequence": "MEQFSDDELDHAAEEDSDKEDQDLDKMFGAWLGELDKLTKSLDDGRPEKVQKAPLRQDSNMANMAYRFSVYNINEALNQGDAVDLDALMADLCSIEQELSTIGKPSSSSSRLGLTGDTKLRQKPPAGRSHSTKHTGGSSSSGGSTSSSTRASPASTVRLSSSSSSSRPPLASNFSLDDITAQLEKASQSMDEAARQGSTPSAAYSSSTVRRPASHHHHHRRTGSVGTVTEHEVRSFVHSSRASINSASASSMDSLDIDKPLSDQDGVQDGQGQPSTEHSYLDRETSLILKSIAGKPSHLLTKEEQAAKQKAEKIRVALEKIKEAQVKKLVVRVHLSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSLDWSLVEIITELQMERIFEDHENLVENLLNWTRDSTNRLMFIERIEKYALFKNPQNYLLGRKETCEMADRNKEALLEECFGGSTISVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLDHVNVYLGQDYRSKYKAPTDYCMVLKHPQIQKKSQYIKYLCCDDVRMLHQWVNGIRIAKYGKQLYVNYQEAMRRTEAAHDWSSLSSSSIKSCSSSSSLPESQSNHSSQSDSGVSETTSSGHVRSQSVVSSIFSEAWKRGNQADEPKDENVESGKL", "length": 658, "header": "tr|A0AC58GE81-1|A0AC58GE81_DANRE Computationally mapped isoform of Ras-associated and pleckstrin homology domains-containing protein 1a isoform X4 OS=Danio rerio OX=7955 GN=raph1a PE=1 SV=1 CANONICAL=A0A8N7UQQ7-1" }, "locus": {} }, { "isoform_ac": "A0AC58GE90-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7/entry#A0AC58GE90-1", "sequence": { "sequence": "MEQFSDDELDHAAEEDSDKEDQDLDKMFGAWLGELDKLTKSLDDGRPEKVQKAPLRQDSNMANMAYRFSVYNINEALNQGDAVDLDALMADLCSIEQELSTIGKPSSSSSRLGLTGDTKLRQKPPAGRSHSTKHTGGSSSSGGSTSSSTRASPASTVRLSSSSSSSRPPLASNFSLDDITAQLEKASQSMDEAARQGSTPSAAYSSSTVRRPASHHHHHRRTGSVGTVTEHEVRSFVHSSRASINSASASSMDSLDIDKPLSDQDGVQDGQGQPSTEEEQAAKQKAEKIRVALEKIKEAQVKKLVVRVHLSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSLDWSLVEIITELQMERIFEDHENLVENLLNWTRDSTNRLMFIERIEKYALFKNPQNYLLGRKETCEMADRNKEALLEECFGGSTISVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLDHVNVYLGQDYRSKYKAPTDYCMVLKHPQIQKKSQYIKYLCCDDVRMLHQWVNGIRIAKYGKQLYVNYQEAMRRTEAAHDWSSLSSSSIKSCSSSSSLPESQSNHSSQSDSGVSETTSSGHVRSQSVVSSIFSEAWKRGNQADEPKDENVESGKL", "length": 633, "header": "tr|A0AC58GE90-1|A0AC58GE90_DANRE Computationally mapped isoform of Ras-associated and pleckstrin homology domains-containing protein 1a isoform X5 OS=Danio rerio OX=7955 GN=raph1a PE=1 SV=1 CANONICAL=A0A8N7UQQ7-1" }, "locus": {} }, { "isoform_ac": "A0AC58GE96-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7/entry#A0AC58GE96-1", "sequence": { "sequence": "MASCWKSQEEQAAKQKAEKIRVALEKIKEAQVKKLVVRVHLSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSLDWSLVEIITELQMERIFEDHENLVENLLNWTRDSTNRLMFIERIEKYALFKNPQNYLLGRKETCEMADRNKEALLEECFGGSTISVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLDHVNVYLGQDYRSKYKAPTDYCMVLKHPQIQKKSQYIKYLCCDDVRMLHQWVNGIRIAKYGKQLYVNYQEAMRRTEAAHDWSSLSSSSIKSCSSSSSLPESQSNHSSQSDSGVSETTSSGHVRSQSVVSSIFSEAWKRGNQADEPKMRIDGPPAQPARASYPLQLPPLPQSLQSRSSYSGVSPASPSSPPSPPPPPPPPPPLPNPTHHSTPVVFTKYSTLARLQNISQAPNHYKQTPLLAAQQQPTPPVPPPQCLKPLMNNTTEVASSPPPAPPPPPPPEMPVPGSAMAVLKHAPISPQYTPPPPPEEDPSYLHSNGYLPPPPPPEQLKYPPPLSTNGLQQFLAQKFPNMTYDFSPVQQDEEPPPPPPVCFSPPPQQSGPPAPPKTFTGGFPPQTAPKPGHGISPISPVPPSLSPTPSLMKKQQSLSSGHSPNQPPPTLPKQYSLSSKAPSVSAPISPTQSLVKQIVNQFPDTLDGSKGPISPPVVKNKPKWQPGGQAQPQSPEFPPPPPESTLEFPPPPAPSPPPASQPSGKSGSPIKKSPSTSSNSSTGSGGKKPPPTPQRNSSMKATSSVEYQESKKVEDLVSMFGQTSQAPPSSFSTPSSTTGSPSKESSRALTKPGKINLANLPLALQGRQSHCRQSSADFPSPPLDCEFPPPPPDSELLPPPPLPSELHIGAPKVAVVNPQPQHSSSSTSSWKQSSLKKMPPPTMHRRSSGPPEQLALSPPPQQMPLSSFNSQIPPTSPKANLSMQPNFLEDLNRTLKRKSMTRHGSLTSSRISAKLEPVATMDDMALPPPPPELLLGQQKKGGYTSANISGYATLRRGPPPAPPKRDQNTKLTSEW", "length": 1052, "header": "tr|A0AC58GE96-1|A0AC58GE96_DANRE Computationally mapped isoform of Ras-associated and pleckstrin homology domains-containing protein 1a isoform X3 OS=Danio rerio OX=7955 GN=raph1a PE=3 SV=1 CANONICAL=A0A8N7UQQ7-1" }, "locus": {} }, { "isoform_ac": "A0AC58GE97-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7/entry#A0AC58GE97-1", "sequence": { "sequence": "MEQFSDDELDHAAEEDSDKEDQDLDKMFGAWLGELDKLTKSLDDGRPEKVQKAPLRQDSNMANMAYRFSVYNINEALNQGDAVDLDALMADLCSIEQELSTIGKPSSSSSRLGLTGDTKLRQKPPAGRSHSTKHTGGSSSSGGSTSSSTRASPASTVRLSSSSSSSRPPLASNFSLDDITAQLEKASQSMDEAARQGSTPSAAYSSSTVRRPASHHHHHRRTGSVGTVTEHEVRSFVHSSRASINSASASSMDSLDIDKPLSDQDGVQDGQGQPSTEEEQAAKQKAEKIRVALEKIKEAQVKKLVVRVHLSDESSKTMMVDERQTVRQVLDSLLDKSHCGYSLDWSLVEIITELQMERIFEDHENLVENLLNWTRDSTNRLMFIERIEKYALFKNPQNYLLGRKETCEMADRNKEALLEECFGGSTISVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKASRDLVCFLQLDHVNVYLGQDYRSKYKAPTDYCMVLKHPQIQKKSQYIKYLCCDDVRMLHQWVNGIRIAKYGKQLYVNYQEAMRRTEAAHDWSSLSSSSIKSCSSSSSLPESQSNHSSQSDSGVSETTSSGHVRSQSVVSSIFSEAWKRGNQADEPKMRIDGPPAQPARASYPLQLPPLPQSLQSRSSYSGVSPASPSSPPSPPPPPPPPPPLPNPTHHSTPVVFTKYSTLARLQNISQAPNHYKQTPLLAAQQQPTPPVPPPQCLKPLMNNTTEVASSPPPAPPPPPPPEMPVPGSAMAVLKHAPISPQYTPPPPPEEDPSYLHSNGYLPPPPPPEQLKYPPPLSTNGLQQFLAQKFPNMTYDFSPVQQDEEPPPPPPVCFSPPPQQSGPPAPPKTFTGGFPPQTAPKPGHGISPISPVPPSLSPTPSLMKKQQSLSSGHSPNQPPPTLPKQYSLSSKAPSVSAPISPTQSLVKQIVNQFPDTLDGSKGPISPPVVKNKPKWQPGGQAQPQSPEFPPPPPESTLEFPPPPAPSPPPASQPSGKSGSPIKKSPSTSSNSSTGSGGKKPPPTPQRNSSMKATSSVEYQESKKVEDLVSMFGQTSQAPPSSFSTPSSTTGSPSKESSRALTKPGKINLANLPLALQGRQSHCRQSSADFPSPPLDCEFPPPPPDSELLPPPPLPSELHIGAPKVAVVNPQPQHSSSSTSSWKQSSLKKMPPPTMHRRSSGPPEQLALSPPPQQMPLSSFNSQIPPTSPKANLSMQPNFLEDLNRTLKRKSMTRHGSLTSSRISAKLEPVATMDDMALPPPPPELLLGQQKKGGYTSANISGYATLRRGPPPAPPKRDQNTKLTSEW", "length": 1321, "header": "tr|A0AC58GE97-1|A0AC58GE97_DANRE Computationally mapped isoform of Ras-associated and pleckstrin homology domains-containing protein 1a isoform X2 OS=Danio rerio OX=7955 GN=raph1a PE=1 SV=1 CANONICAL=A0A8N7UQQ7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1063, "start_aa": "Thr", "end_pos": 1063, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1063", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1104, "start_aa": "Thr", "end_pos": 1104, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1104", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 749, "start_aa": "Thr", "end_pos": 749, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr749", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 919, "start_aa": "Thr", "end_pos": 919, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr919", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 962, "start_aa": "Thr", "end_pos": 962, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr962", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:557435", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557435", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A272-1", "protein_name": "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1", "gene_name": "Raph1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQLSDEEIDHGAEEDSDKEDQDLDKMFGAWLGELDRLTQSLDSDKPKEPVKRSPLRQETNMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSVGSGNSKRQVTEPKVAQKLPASRHTSKHGTLRGVSSSSTRTTRPPHANYSLDDITAQLEQASLSMDEAAQQSAVEDAKPPATNQHRRTASAGTVSDAEVRSVSNSSRSSITSAASSMDSLDIDKVTRPQELDLTAHQGKPITEHATSLSCPSKQAKHHSDFTEEQAQLAPHSYLDRETSLLLRNIAGKPSHLLTKEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGKKETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDCCLALKHPQIQKKSQYIKYLCCDDARTLHQWVNGIRIAKYGKQLYTNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTLPSGHIRSQSTVSSIFSEAWKRGTQLEESSKARMESMNRSYTSLMPPLSPQTKIITPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSSGSAATMFVKYSTITRLQNAAQHSGTLFKSPAPSAMQPLPLASQSKAQIVVPPNGVIPPPPPPPPPPTPGSAMAQLKPVPCAPSLPQFSPQPPPLKIHQVQHLPQAAPPTPPAAPLIPATVPPQAPPKPLVTIPPSASTKMVSPVVAQAVPPTPAPPVPPTKKQPVFPVSHIPPTPPVQPTPHPPPTLPKQQSFGVKPPPSPLSPVPSVVKQMASQFPPPPTPPPVDSQPLKPLPASVTPQSPPAVKAKPKWQPSSIPAPSPDFPPPPPESSLVFPPPPPPAPVPPPPPPPPPPPPPPPVSPMASPTPDKGGSPGKKTSKMSSPGGKKPPPTPQRNSSIKSGSCAEHPEPKRPSVDSLVSKFAPPAESGSPSKETPPPPAAPPKPGKLHLSGVNLPGIHQQGILSAKPSVLSGRGKDAVVEFPSPPSDSDFPPPPPEIELPLPPIEIPAVFSGNTSPKVAVVNPQPQLWSKTSVKKAPPPTRPKRNDSTRLTQADISEQPAMTTVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGFGGSHISGYATLRRGPPPAPPKRDQNTKLSRDW", "length": 1318 }, "evidence": [ { "id": "HGNC:14436", "url": "https://alliancegenome.org/gene/HGNC:14436#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-156#orthology", "database": "AGR" }, { "id": "MGI:1924550", "url": "https://alliancegenome.org/gene/MGI:1924550#orthology", "database": "AGR" }, { "id": "RGD:1308387", "url": "https://alliancegenome.org/gene/RGD:1308387#orthology", "database": "AGR" }, { "id": "FB:FBgn0261811", "url": "https://alliancegenome.org/gene/FB:FBgn0261811#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3AQ39-1", "protein_name": "Ras-associated and pleckstrin homology domains-containing protein 1b isoform 1", "gene_name": "raph1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEQVSDDELDHAAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDDGRPEKVQKAPLRQETNLANFSYRFSMYNINEAINQGETVDLDALMADLCSIEQELSTIGKPISKTLDGKSKQRPTGRSASAKHSGGGSSGGSTSSSTRASPASTVRGGNSQSRPLASNFSLDDITAQLEKASLSMDEAAKQTSESSSSSYSSANPPSNSHHRRTGSVGTVSDQEVRSIGHSSRSSVNSASASSMDSLDIRGQENETQSQNQSQTSTEHVLLRRANGKTTRRHLDFTSQEGEVDQSTHSYLDRETSLILKNIAGKPSHLLTKEEQAAKAKAEKIRVALEKIKEAQVKKLVIRVHMSDESSKTMMVDERQTVRQLLDSLLDKSHCGYSPDWALVETIPELQMERIFEDHENLVENLLNWTRDSQNKLMFIERIEKYALFKNPQNYLLGRKETSEMADRNKEALLEECFCGSSVSVPEIEGVLWLKEDGKKSWKKRYFLLRASGIYFVPKGKAKASRDLVCFLQLDHVNVYYGQDYRSKYKAPTDYCLALKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYVNYQEAMKRTEAAYDWSSLSSTSIKSGTSSVSIPESQSNHSSQTDSGMSDGTSSSHARSQSVVSSIFSEAWKRGTQIEESTKARPESIRSTHSSHSSHSSHHVSQQQHLHAQQPHVHSILQSRGSVTQAPAQAPTQTLAQAPPQVAPAPPPPPPPPPPPPPPPISSIPHHATPTMFAKYSTITRLQNASQATSHHKPQPQIQQQVPPVPPPSKPQSNNIPSGANIPPPPPPPPPASMPPPGSAMAVLKLGPPAAAVIPQISPSPPSPPPPPPPPPIMPVQSQPQPPPPPIMPMQSQPLPPPPPITPMQSHNLPPPPPMQSHALPPPPPITPMQSHALPPPPPITPMQSHALPPPPPITPMQSHALPPPPPITPMQSHALPPPPPIMPMQSEPLPPPAQIMPMQSHPLPPPPPLVQMQSQPMPPPPPTVSFQSQPLPPPPPPLQANGLPPPPPLITNGLKQAFAHKFPSTPQDVLPPANQNNFPPPPPPPPPPPLAPTLPPYQHVTSTSNPPPPPPPPPPPPPAPIHLANQPAVLPKFFTGGFPPQKAPKPSCGILPVSPVAPALQPPPPPPPPPPPPPPAPLKNQPPPTLPKQHSLSKTLPFSSQTSSVPSMVKQLASQFPVASPALTNQTDSLKAPQSPPAVKVKPKWQPVGQGQQQQRSPEFPPPPPDNALGFASPTPPPPPPPPLPPGPTPPPPPPPPPLMSGSPIKKSPSGSSAGVKKPPPTPQRNSSVKYDASTEYQESRKNLVSKFNPSSASSTTSTSSCSPSKELSAGPQAPPKPGKLNLANLPLALQNKFNQNRQSAADFPSPPPPENDFFPPPPIESDLPPPPPLPGDLNGVSPKVAVVNPQPQPAWGKSSLKKTQPPASLRCNNTVRESPPLSPPSIHGGPIPHSPKGTTQPNFLEDLNKTLKRKSSRVSGDKVDPVATMDDMVLPPPPPELLQDQQRLSGSGFMSGNISGYATLRRGPPPAPPKRDHSTKLTN", "length": 1565 }, "evidence": [ { "id": "HGNC:14436", "url": "https://alliancegenome.org/gene/HGNC:14436#orthology", "database": "AGR" }, { "id": "MGI:1924550", "url": "https://alliancegenome.org/gene/MGI:1924550#orthology", "database": "AGR" }, { "id": "RGD:1308387", "url": "https://alliancegenome.org/gene/RGD:1308387#orthology", "database": "AGR" }, { "id": "FB:FBgn0261811", "url": "https://alliancegenome.org/gene/FB:FBgn0261811#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F2Z3U3-1", "protein_name": "Ras association (RalGDS/AF-6) and pleckstrin homology domains 1", "gene_name": "Raph1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEQLSDEEIDHGAEEDSDKEDQDLDKMFGAWLGELDRLTQSLDSDKPKEPVKRSPLRQETNMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSIGSGNSKRQVTEPKVPQKLPAGRHTSKHGTLRGPSSSSNRTTKPSHANYSLDDITAQLEQASLSMDEAAQQSLVEDPKPLVTNQHRRTASAGTVSDAEARSISNSSRSSITSAASSMDSLDIDKVTRPQELDLTTHQGQPITEEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETISELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGKKETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDCCLALKHPQIQKKSQYIKYLCCDDARTLHQWVNGIRIAKYGKQLYTNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTLPTGHIRSQSTVSSIFSEAWKRGTQLEESSKARMESMNRSYTSLMPPLSPQTKIITPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSSGSAATMFVKYSTITRLQNAAQHSGTLFKSPTPPAMQPLPLASQSKAQIVVPPNGVIPPPPPPPPPPTPGSAMAQLKPVPCAPSLPQFSPQPPPLKIHQVQHLPQTAPPTPPPAPPITATVPPQAPPKPLVTIPPSASTKTVSPVVAQAVPPTPAPPVPPAKKQPVFPVSHIPPTPPVQPTPHPPPTLPKQQSFGVKPPPSPLSPVPSVVKQIASQFPPPPTPPPVDSQPLKSLPASGTPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPPAPAPAPPPPPPPPPPPPPVPPTASPTPDKGGSPGKKTSKMSSPGGKKPPPTPQRNSSIKSGSCAEHPEPKRPSVDSLVSKFAPPAESGSPSKETPPPPAAPPKPGKLHLSGVNLPGIHQQGIVSAKASVLSGRGKDVVVEFPSPPSDSDFPPPPPEIELPLPPIEIPAVFSGNTSPKVAVVNPQPQLWSKTSVKKAPPPTRPKRNDSTRLTQADISEQPAMTTVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGFGGSHISGYATLRRGPPPAPPKRDQNTKLSRDW", "length": 1266 }, "evidence": [ { "id": "HGNC:14436", "url": "https://alliancegenome.org/gene/HGNC:14436#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-156#orthology", "database": "AGR" }, { "id": "MGI:1924550", "url": "https://alliancegenome.org/gene/MGI:1924550#orthology", "database": "AGR" }, { "id": "RGD:1308387", "url": "https://alliancegenome.org/gene/RGD:1308387#orthology", "database": "AGR" }, { "id": "FB:FBgn0261811", "url": "https://alliancegenome.org/gene/FB:FBgn0261811#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q05683-1", "protein_name": "Glutamate decarboxylase 2", "gene_name": "Gad2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASPGSGFWSFGSEDGSGDPENPGTARAWCQVAQKFTGGIGNKLCALLYGDSEKPAESGGSVTSRAATRKVACTCDQKPCSCPKGDVNYALLHATDLLPACEGERPTLAFLQDVMNILLQYVVKSFDRSTKVIDFHYPNELLQEYNWELADQPQNLEEILTHCQTTLKYAIKTGHPRYFNQLSTGLDMVGLAADWLTSTANTNMFTYEIAPVFVLLEYVTLKKMREIIGWPGGSGDGIFSPGGAISNMYAMLIARYKMFPEVKEKGMAAVPRLIAFTSEHSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSDLERRILEVKQKGFVPFLVSATAGTTVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLNGVERANSVTWNPHKMMGVPLQCSALLVREEGLMQSCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLMWRAKGTTGFEAHIDKCLELAEYLYNIIKNREGYEMVFDGKPQHTNVCFWFVPPSLRVLEDNEERMSRLSKVAPVIKARMMEYGTTMVSYQPLGDKVNFFRMVISNPAATHQDIDFLIEEIERLGQDL", "length": 585 }, "evidence": [ { "id": "FB:FBgn0261811", "url": "https://alliancegenome.org/gene/FB:FBgn0261811#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PFT9-1", "protein_name": "Amyloid beta A4 precursor protein-binding family B member 1-interacting protein", "gene_name": "apbb1ip", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDDIDAMFSDMLQEMDLLTQSLDAEVDSAPLAKPPTIPEPQEMNFSIGFANFNESLNDLEDNDLDALMADLVADISATEEKFATERDTSKGSVPVAPAPSKPQSNFSLPASFDSSKPATSSNSIAAPPPPPAFKPSKEEEEEQLKADKIKLALEKLKEAKVKKLVVKVEITDGSSKTLMVDERQTVRDVMDNLFEKTHCDCNVDWSVCETNPDLQTERAFEDHENLVEPLSTWTRDTENKVLFQEKKHKYEVFKNPQIFYLWKKDKKSLKDMKEKDKEQLLEENFCGASVIVPDLEGVLYLKEDGKKSWKQRYFLLRASGLYYSPKGKTKASRDLVCLVQFDNVNVYYCKEYRIKYKAPTDHCFMLKHPQIQKESQYIKFMCCDDEWSMNLWVTGIRVAKYGKQLYDNYKAAVRKASGSASWANRTIQASSTASTPSPTPKAKAANGHAPQPPVENKVPSNQSSLPPPPPSMDFLPPPPPDPMFPPPPPAPPAPPAPPVPVSSTKVNKFPPPPKFPQSSFPPPPMDDLPPPPPPPEIADLPPDFLPPPPPSFVSHGGESLPPPPPDPVASLPPPPPAFTSAGGAPPPPPPPPPPPAPAPAVNNPAGSVRKVAPPPPKRTTPQLAAPSGGDFMSELMNAMQKKRTQP", "length": 646 }, "evidence": [ { "id": "FB:FBgn0261811", "url": "https://alliancegenome.org/gene/FB:FBgn0261811#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q70E73-10", "protein_name": "Ras-associated and pleckstrin homology domains-containing protein 1", "gene_name": "RAPH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEQLSDEEIDHGAEEDSDKEDQDLDKMFGAWLGELDKLTQSLDSDKPMEPVKRSPLRQETNMANFSYRFSIYNLNEALNQGETVDLDALMADLCSIEQELSSIGSGNSKRQITETKATQKLPVSRHTLKHGTLKGLSSSSNRIAKPSHASYSLDDVTAQLEQASLSMDEAAQQSVLEDTKPLVTNQHRRTASAGTVSDAEVHSISNSSHSSITSAASSMDSLDIDKVTRPQELDLTHQGQPITEEEQAAKLKAEKIRVALEKIKEAQVKKLVIRVHMSDDSSKTMMVDERQTVRQVLDNLMDKSHCGYSLDWSLVETVSELQMERIFEDHENLVENLLNWTRDSQNKLIFMERIEKYALFKNPQNYLLGKKETAEMADRNKEVLLEECFCGSSVTVPEIEGVLWLKDDGKKSWKKRYFLLRASGIYYVPKGKAKVSRDLVCFLQLDHVNVYYGQDYRNKYKAPTDYCLVLKHPQIQKKSQYIKYLCCDDVRTLHQWVNGIRIAKYGKQLYMNYQEALKRTESAYDWTSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDTQPAGHVRSQSIVSSVFSEAWKRGTQLEESSKARMESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHISGYATLRRGPPPAPPKRDQNTKLSRDW", "length": 1250 }, "evidence": [ { "id": "HGNC:14436", "url": "https://alliancegenome.org/gene/HGNC:14436#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-156#orthology", "database": "AGR" }, { "id": "MGI:1924550", "url": "https://alliancegenome.org/gene/MGI:1924550#orthology", "database": "AGR" }, { "id": "RGD:1308387", "url": "https://alliancegenome.org/gene/RGD:1308387#orthology", "database": "AGR" }, { "id": "FB:FBgn0261811", "url": "https://alliancegenome.org/gene/FB:FBgn0261811#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7Z5R6-1", "protein_name": "Amyloid beta A4 precursor protein-binding family B member 1-interacting protein", "gene_name": "APBB1IP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGESSEDIDQMFSTLLGEMDLLTQSLGVDTLPPPDPNPPRAEFNYSVGFKDLNESLNALEDQDLDALMADLVADISEAEQRTIQAQKESLQNQHHSASLQASIFSGAASLGYGTNVAATGISQYEDDLPPPPADPVLDLPLPPPPPEPLSQEEEEAQAKADKIKLALEKLKEAKVKKLVVKVHMNDNSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERFFEDHENVVEVLSDWTRDTENKILFLEKEEKYAVFKNPQNFYLDNRGKKESKETNEKMNAKNKESLLEESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNIYYGTQHKMKYKAPTDYCFVLKHPQIQKESQYIKYLCCDDTRTLNQWVMGIRIAKYGKTLYDNYQRAVAKAGLASRWTNLGTVNAAAPAQPSTGPKTGTTQPNGQIPQATHSVSAVLQEAQRHAETSKDKKPALGNHHDPAVPRAPHAPKSSLPPPPPVRRSSDTSGSPATPLKAKGTGGGGLPAPPDDFLPPPPPPPPLDDPELPPPPPDFMEPPPDFVPPPPPSYAGIAGSELPPPPPPPPAPAPAPVPDSARPPPAVAKRPPVPPKRQENPGHPGGAGGGEQDFMSDLMKALQKKRGNVS", "length": 666 }, "evidence": [ { "id": "FB:FBgn0261811", "url": "https://alliancegenome.org/gene/FB:FBgn0261811#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R5A3-1", "protein_name": "Amyloid beta A4 precursor protein-binding family B member 1-interacting protein", "gene_name": "Apbb1ip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGESNEDIDQMFSTLLGEMDLLTQSLGVDTLPPPDPNPPREEFNYTVGFKDLNESLNALEDQDLDALMADLVADISEAEQRTIQAQKESSQNQDRFALLRASDGQGTASGGYGASAAAIDVSHHEEALPPPPVEPMLDLLPPPPPPPPPELLSKEEEEAKAKADKIKLALEKLKEAKVKKLVVKVHMDDSSTKSLMVDERQLARDVLDNLFEKTHCDCNVDWCLYEIYPELQIERVFEDHENVVEVLSDWTRDTENKVLFLEKEERYAVFKNPQNFYLDNKGKKENKETNEKMNAKNKEYLLEESFCGTSIIVPELEGALYLKEDGKKSWKRRYFLLRASGIYYVPKGKTKTSRDLACFIQFENVNIYYGIQCKMKYKAPTDHCFVLKHPQIQKESQYIKYLCCDDARTLSQWVMGIRIAKYGKTLYDNYQRAVARAGLASRWTNLGTVGTPMPAQPSTVSSGLKTGTSQPNGQMPQAIPSAGPPLQEAQTQIETTKDEKQGLGNHSPGATRENHRPKSSLPPPPPPVRRSSDTCGSPALPSKVKGPGTCTFPHPPENFLPPPPPPPPEEDNSGLLPPPPPPPYLEEPPDFVPPPPPPAAVEDSALPPPPPPPPCLSQEITKSSPLPPKKPLVPPKRQENQGLPGAPGNSEQDFMSDLMKALQKKRGNIP", "length": 670 }, "evidence": [ { "id": "FB:FBgn0261811", "url": "https://alliancegenome.org/gene/FB:FBgn0261811#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VWB7-1", "protein_name": "Pico, isoform A", "gene_name": "pico", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDCGGIAAHQQQQLQQQQLHLLQQQLQQQHHQQQRQQQQHSLEEAATITNINLRGILVGGAASSAGVAGAAAGGATTTTTTTTAAGFVAGGDCPVIGAGAGAGVKLRRHSDRPLTPEAKQLSHTYRISMANLEDSQESELDQILGELSLLEAQISYTEASMLPAMCAPSAGAQIAPPPGVTQLPGSAPTMVSMSASSSRSHSRTNSTISADVSSCSSSGISENGHGLGLVLGGPGSAGMMVQPPPPGGMTMGITLGVVTPREPRTESPDNDSAFSDTVSLLSSESSASSNTSLQQQQQQQQQQHHQHQQHHQHQQQQQKPQLAGAEKLHHHGVHGQHGGQQSGANSITKADKIQLALHKLESAPIRRLFVKAFTSDGASKSLLVDERMGCGHVTRLLADKNHVQMQSNWALVEHLGDLQMERLFEDHELLVDNLMTWHSDAGNRVLFQQRPDKVTLFLRPELYLPGPQMAPGCQHDEQTRQMLLDEFFDSHNQLQMDGPLYMKADPKKGWKRYHFVLRSSGLYYFPKEKTKNTRDLACLNLFHGHNVYTGLGWRKKWKSPTDYTFGFKAVGDSSLGKSCRSLKMLCAEDLPTLDRWLTAIRVCKYGKQLWDSHKSLLEDLCLSRDDAVSQSSFAASMRSESISSISSAVPSQCGSVSSAISSMSNSTSGRTSRASSSSSSGCLSDDNNAFDSEFTTGTIKRKPSMKPNLPLTTMTRQLKEVGEITICESAGGDASSPERSGTLTRRHSRRKSQESNGSGTLKRRPIAVPVATVVKQTEPMGSASSTSSSSNSTPTPTPSICAKPPPGDSASLMCSSTLSLDSLPPPPPPPALDGSEDQDVYGSQLSLASLPPPPPPEDVLAMNYAEPSSPSTPTPMSTPMIMPNSNGSLPPAVPAKPMKPAVKQAAGGLKAAPPYKAPPDYVGPALLPGPPLPPPPPAQKKVSFADSPVLLRRKMCSPEPVLPQRSPSTTLSCHSSSSAGSAYQTYAPGPMLPPRADVARLSSLSNGSSSEVTSPKRLQESASNPPRDFLKDLQRVMRKKWQVAQKCKAEPATTPHEVLGFRDFSNEDLLAAHNLNSGANSSHYYRETANVSHWVRKHYEYAHNALYENVHAQSAAAAGVPGSGEATTPPLPPPPGNSVAAKKRPPPPPPKRSDKTHLTNRV", "length": 1162 }, "evidence": [ { "id": "HGNC:14436", "url": "https://alliancegenome.org/gene/HGNC:14436#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-156#orthology", "database": "AGR" }, { "id": "MGI:1924550", "url": "https://alliancegenome.org/gene/MGI:1924550#orthology", "database": "AGR" }, { "id": "RGD:1308387", "url": "https://alliancegenome.org/gene/RGD:1308387#orthology", "database": "AGR" }, { "id": "FB:FBgn0261811", "url": "https://alliancegenome.org/gene/FB:FBgn0261811#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7" } ], "pmid": "" }, { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein-macromolecule adaptor activity", "id": "GO:0030674", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030674", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQQ7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQQ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { 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This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_685740.2. 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}, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UQT5-1", "uniprot_ac": "A0A8N7UQT5", "uniprot_id": "A0A8N7UQT5_DANRE", "mass": { "chemical_mass": 24877.0, "monoisotopic_mass": 24877.0 }, "refseq": { "ac": "XP_687069", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687069" }, "gene_names": [ { "name": "LOC108179086", "type": "recommended", "evidence": [ { "id": "A0A8N7UQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQT5" } ] }, { "name": "LOC108179086", "type": "synonym", "evidence": [ { "id": "XP_687069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687069" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8N7UQT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQT5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_687069", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687069" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_687069.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_687069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687069" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQT5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC108179086", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQT5", "locus": {} } ], "crossref": [ { "id": "A0A8N7UQT5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UQT5", "database": "AlphaFoldDB", "categories": [] }, { "id": "108179086", "url": "https://www.ncbi.nlm.nih.gov/gene/108179086", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:108179086", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179086", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UQT5", "url": "https://www.orthodb.org/?gene=A0A8N7UQT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38706", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38706", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38706:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38706:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_687069", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687069", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UQT5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UQT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQT5-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVKGTLNELSQLKQSGFGQPEPRHGLNLLYWFAREYILFDFGEIKPKFNPVFGEFGFHKFNNRIEDEDHIVPIQNLPYYEVGNLNYSNADKLPNYVRQKYSHYNPDSNKDRIIVHQDGNGKLNRVYVTEHSDQRHFDSSKTYRVSNGLLLIIKNMSREDFLSKVSNTGNRTNNQQPFYYQQHSVYQSYSTPVNHTPSPRPPPPAEDSSWCTIL", "length": 213, "header": "tr|A0A8N7UQT5-1|A0A8N7UQT5_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108179086 PE=4 SV=1 CANONICAL=A0A8N7UQT5-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UQT5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQT5/entry#A0A8N7UQT5-1", "sequence": { "sequence": "MVKGTLNELSQLKQSGFGQPEPRHGLNLLYWFAREYILFDFGEIKPKFNPVFGEFGFHKFNNRIEDEDHIVPIQNLPYYEVGNLNYSNADKLPNYVRQKYSHYNPDSNKDRIIVHQDGNGKLNRVYVTEHSDQRHFDSSKTYRVSNGLLLIIKNMSREDFLSKVSNTGNRTNNQQPFYYQQHSVYQSYSTPVNHTPSPRPPPPAEDSSWCTIL", "length": 213, "header": "tr|A0A8N7UQT5-1|A0A8N7UQT5_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC108179086 PE=4 SV=1 CANONICAL=A0A8N7UQT5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:108179086", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:108179086", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 154, "end_pos": 156 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UQW3-1", "uniprot_ac": "A0A8N7UQW3", "uniprot_id": "A0A8N7UQW3_DANRE", "mass": { "chemical_mass": 36637.0, "monoisotopic_mass": 36637.0 }, "refseq": { "ac": "XP_688423", "name": "PI-PLC X domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688423" }, "gene_names": [ { "name": "plcxd2", "type": "recommended", "evidence": [ { "id": "A0A8N7UQW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3" } ] }, { "name": "plcxd2", "type": "synonym", "evidence": [ { "id": "XP_688423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688423" } ] } ], "protein_names": [ { "name": "PI-PLC X domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_688423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688423" }, { "id": "A0A8N7UQW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_688423.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_688423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688423" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQW3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "plcxd2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-217", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UQW3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UQW3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd08616", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08616", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "559936", "url": "https://www.ncbi.nlm.nih.gov/gene/559936", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UQW3", "url": "https://www.orthodb.org/?gene=A0A8N7UQW3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13593", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13593", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13593:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13593:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00388", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00388", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_688423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UQW3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UQW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRK3", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRK3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-217", "url": "https://zfin.org/ZDB-GENE-091204-217", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKTRPTGNTSNADWMGSLCPALTSMPLKHLAVPGSHDSFSFWVDEQAPVGPDQKAYVKHLAAIFRFLAKKVMKKWSMTQNLTFREQLEGGIRYFDLRVSSKPGEAGHEIYFIHGLFGHKVRDGLNDINNFLNIHKKEVVFLDFNHHYAMGEEHHRYLIKMLQDVFGHKLCRIDVVEEITLNYLWENRYQVLVFYHHPSAEGCPVMWPGSKIPAPWANTTDTTKLIQFLETTLGERAKYGSFHVSQAILTPRVKTIARGLVQGLRNYLVERNLPTIMTWVEAQKPGKDGVNIITSDFVELVDFANTVIKLNTLLIKDRDTK", "length": 320, "header": "tr|A0A8N7UQW3-1|A0A8N7UQW3_DANRE Isoform 1 of PI-PLC X domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=plcxd2 PE=4 SV=1 CANONICAL=A0A8N7UQW3-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UQW3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3/entry#A0A8N7UQW3-1", "sequence": { "sequence": "MKTRPTGNTSNADWMGSLCPALTSMPLKHLAVPGSHDSFSFWVDEQAPVGPDQKAYVKHLAAIFRFLAKKVMKKWSMTQNLTFREQLEGGIRYFDLRVSSKPGEAGHEIYFIHGLFGHKVRDGLNDINNFLNIHKKEVVFLDFNHHYAMGEEHHRYLIKMLQDVFGHKLCRIDVVEEITLNYLWENRYQVLVFYHHPSAEGCPVMWPGSKIPAPWANTTDTTKLIQFLETTLGERAKYGSFHVSQAILTPRVKTIARGLVQGLRNYLVERNLPTIMTWVEAQKPGKDGVNIITSDFVELVDFANTVIKLNTLLIKDRDTK", "length": 320, "header": "tr|A0A8N7UQW3-1|A0A8N7UQW3_DANRE Isoform 1 of PI-PLC X domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=plcxd2 PE=4 SV=1 CANONICAL=A0A8N7UQW3-1" }, "locus": {} }, { "isoform_ac": "A0AC58IRK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3/entry#A0AC58IRK3-1", "sequence": { "sequence": "MKKWSMTQNLTFREQLEGGIRYFDLRVSSKPGEAGHEIYFIHGLFGHKVRDGLNDINNFLNIHKKEVVFLDFNHHYAMGEEHHRYLIKMLQDVFGHKLCRIDVVEEITLNYLWENRYQVLVFYHHPSAEGCPVMWPGSKIPAPWANTTDTTKLIQFLETTLGERAKYGSFHVSQAILTPRVKTIARGLVQGLRNYLVERNLPTIMTWVEAQKPGKDGVNIITSDFVELVDFANTVIKLNTLLIKDRDTK", "length": 249, "header": "tr|A0AC58IRK3-1|A0AC58IRK3_DANRE Computationally mapped isoform of PI-PLC X domain-containing protein 2 isoform X2 OS=Danio rerio OX=7955 GN=plcxd2 PE=4 SV=1 CANONICAL=A0A8N7UQW3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9Q712-1", "protein_name": "PI-PLC X domain-containing protein 1 isoform X1", "gene_name": "plcxd1.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEQIREDDNQEDWMSRLPEKLLDIPLTNLAIPGETMKTIGESKGSHDAMSYCLDINSPLLRSESDTFRLLDGVFYCFTRPFIYRWATTQVINIVEQLQAGIRYFDLRVAHKQYDTSSELYFTHIIYTHATVIETLETVNLWLESHPKEIIILACRNFEGMSDELHEGFIYALKNIFRSKLCPVNETLVTLRRLWALGCQVVLSYEDPQSTIRHKELWPAIQYLWANKPNAEELIQYMECKKQLGRPEGFFVAGLNLTTDRCFIASNPQESLKTLTKKYWNRVQEWLKEQKPGAEPPCLNIIAGDFIGLLPICSLVISLNKKLL", "length": 323 }, "evidence": [ { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B2RXA1-1", "protein_name": "PI-PLC X domain-containing protein 2", "gene_name": "Plcxd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAFRKARRKLRMGTICSPNPSGTKTASEVCNADWMASLPAHLHNVPLSNLAIPGSHDSFSYWVDEKSPVGPDQTQAVIRLARISLVKKLMKKWSVTQNLTFREQLEAGIRYFDLRVSSKPGDTDQEIYFIHGLFGIKVWDGLMEIDAFLTQHPQEIIFLDFNHFYAMDESHHKCLVLRIQEAFGNKLCPACSVESMTLRSLWEKKYQVLIFYHCPFYKQYPFLWPGKKIPAPWANTTSVQKLILFLETTLSERAPRGAFHVSQAILTPRVKTIARGLVGGLKNTLVHRNLPAILDWVKTQKPGAMGVNIITSDFVDLIDFATTVIELNDLLEDRALTKC", "length": 340 }, "evidence": [ { "id": "HGNC:26462", "url": "https://alliancegenome.org/gene/HGNC:26462#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-217#orthology", "database": "AGR" }, { "id": "RGD:1563504", "url": "https://alliancegenome.org/gene/RGD:1563504#orthology", "database": "AGR" }, { "id": "MGI:3647874", "url": "https://alliancegenome.org/gene/MGI:3647874#orthology", "database": "AGR" }, { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" }, { "id": "FB:FBgn0032402", "url": "https://alliancegenome.org/gene/FB:FBgn0032402#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A1H2-1", "protein_name": "Phosphatidylinositol-specific phospholipase C, X domain containing 3", "gene_name": "Plcxd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASSQGKNELKFADWMATLPESIHSIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQNFVSVFGTVAKKLMRKWLATQTMSFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFAQEVSLKYLWEKSYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQASITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWIRTQKPGESGINIVTADFVELGDFISTVIKLNYVFDEGEANT", "length": 321 }, "evidence": [ { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" }, { "id": "FB:FBgn0032402", "url": "https://alliancegenome.org/gene/FB:FBgn0032402#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A4P6-1", "protein_name": "Phosphatidylinositol-specific phospholipase C, X domain containing 2", "gene_name": "Plcxd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAFRKARRKLRMGTICSPNPSGTKTASEVCNADWMASLPPHLHNVPLSNLAIPGSHDSFSYWVDEKSPVGPDQTQAVKRLARISLVKKLMKKWSVTQNLTFREQLEAGIRYFDLRVSSKPGDTDQEIYFIHGLFGIKVWDGLMEIDAFLTQHPQEIIFLDFNHFYAMDEAHHKCLVLRIQEAFGNKLCPACSVESMTLRTLWEKKYQVLIFYHCPFYKQYPFLWPGKKIPAPWANTTSVQKLILFLETTLSERAPRGAFHVSQAILTPRVKTIARGLVGGLKNTLVHRNLPAILDWVKTQKPGAMGVNIITSDFVDLIDFATTVIELNDLLEDRALTKC", "length": 340 }, "evidence": [ { "id": "HGNC:26462", "url": "https://alliancegenome.org/gene/HGNC:26462#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-217#orthology", "database": "AGR" }, { "id": "RGD:1563504", "url": "https://alliancegenome.org/gene/RGD:1563504#orthology", "database": "AGR" }, { "id": "MGI:3647874", "url": "https://alliancegenome.org/gene/MGI:3647874#orthology", "database": "AGR" }, { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" }, { "id": "FB:FBgn0032402", "url": "https://alliancegenome.org/gene/FB:FBgn0032402#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R583-1", "protein_name": "Phosphatidylinositol-specific phospholipase C, X domain containing 1", "gene_name": "Plcxd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDQADWMSQLCPRLWDVPLHHLSIPGSHDTMTYCLNRKSPISRARSRLLHLLGRVLPFLTGPAVMKWAVTQTLDVTRQLDAGVRYLDLRIAHAPGGSARNLCFVHMMYTKALVEDTLTEIAEWLQLHPREVVIVACRDFEGMTREMHDYLVGCIVNIFGDTLCPSGEVPTLGQLWAREQQVLVSYEDEATVSRHDELWPAIPYWWGNAVKTDVLLQFLETKKGHGRPGGLFVAGINVTENLCYVLLHPGDSLEEMTRRSVPLTTQWVRAQQPGQRPHCTNIIAGDFVGADGFVSDVISLNQKLVSP", "length": 307 }, "evidence": [ { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0VAA5-1", "protein_name": "PI-PLC X domain-containing protein 2", "gene_name": "PLCXD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLAVRKARRKLRMGTICSPNPSGTKTSSEVCNADWMASLPPHLHNLPLSNLAIPGSHDSFSYWVDEKSPVGPDQTQAIKRLARISLVKKLMKKWSVTQNLTFREQLEAGIRYFDLRVSSKPGDADQEIYFIHGLFGIKVWDGLMEIDSFLTQHPQEIIFLDFNHFYAMDETHHKCLVLRIQEAFGNKLCPACSVESLTLRTLWEKNCQVLIFYHCPFYKQYPFLWPGKKIPAPWANTTSVRKLILFLETTLSERASRGSFHVSQAILTPRVKTIARGLVGGLKNTLVHSNRWNSHGPSLLSQERS", "length": 305 }, "evidence": [ { "id": "HGNC:26462", "url": "https://alliancegenome.org/gene/HGNC:26462#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-217#orthology", "database": "AGR" }, { "id": "RGD:1563504", "url": "https://alliancegenome.org/gene/RGD:1563504#orthology", "database": "AGR" }, { "id": "MGI:3647874", "url": "https://alliancegenome.org/gene/MGI:3647874#orthology", "database": "AGR" }, { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" }, { "id": "FB:FBgn0032402", "url": "https://alliancegenome.org/gene/FB:FBgn0032402#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q567I4-1", "protein_name": "PI-PLC X domain-containing protein 1", "gene_name": "plcxd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEDEDCYEDWMSKMPSHMWDIPLWNLAIPGSHDSMTYCLDKQSSVSNSTPRVVQVLDKYFPCIVRPCIMKWATTQEGAISNQLDLGIRFLDLRIAHKIKDPDEVFYFAHGVYSLLTVKEALTEVVRWLDQHIKEVVIIALSNFEGMNLDQHKDLIQFLIATFNKKICPKSVTPSLQECWNHSYQVILSYDDESSTGYVELWPQCPYWWANKSDPNLVISYLEDQKNEGRPSQFFAAGLNLTEDARYVLCHPCQSLQSMTRRSYSLLMKWVKQQRPGSGQACLNIICADFVGIFGSESTQLVIGLNQIEA", "length": 309 }, "evidence": [ { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q58EK3-1", "protein_name": "PI-PLC X domain-containing protein 3", "gene_name": "plcxd3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASSQGKSELRYADWMSSLPDTLHGIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQNFVSVFGTVAKKLMRKWLATQTMNFTSQLEAGIRFFDLRISTKPRDPDNELYFAHGLFSATVREGLEQISTFLASHAREVVFLDFNHFYGVQNLHHEKLVQMLRTVFGDRLCPVVFAQEVSLKYLWEKEYQVLVFYHNPMALEVPFLWPGQMMPAPWANTTDPEKLILFLQASVKDRRRKGTFFVSQVVLTPKASTVMKGVTSGLRETITERALPSMMQWIRSQRPGESGVNIITADFVELGEFISAVITLNYYLDDEEENAT", "length": 322 }, "evidence": [ { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" }, { "id": "FB:FBgn0032402", "url": "https://alliancegenome.org/gene/FB:FBgn0032402#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q63HM9-1", "protein_name": "PI-PLC X domain-containing protein 3", "gene_name": "PLCXD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASSQGKNELKLADWMATLPESMHSIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQNFVSVFGTVAKKLMRKWLATQTMNFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKDIYGNKMCPAIFAQEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQASITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWVRTQKPGESGINIVTADFVELGDFISTVIKLNYVFDEGEANT", "length": 321 }, "evidence": [ { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" }, { "id": "FB:FBgn0032402", "url": "https://alliancegenome.org/gene/FB:FBgn0032402#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BLJ3-1", "protein_name": "PI-PLC X domain-containing protein 3", "gene_name": "Plcxd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSQGKNELKFADWMATLPESIHSIPLTNLAIPGSHDSFSFYIDEASPVGPEQPETVQNFVSVFGTVAKKLMRKWLATQTMSFTGQLGAGIRYFDLRISTKPRDPDNELYFAHGLFSAKVNEGLEEINAFLTDHHKEVVFLDFNHFYGMQKYHHEKLVQMLKNIYGNKMCPAIFAQEVSLKYLWEKDYQVLVFYHSPVALEVPFLWPGQMMPAPWANTTDPEKLIQFLQASITERRKKGSFFISQVVLTPKASTVVKGVASGLRETITERALPAMMQWIRTQKPGESGINIVTADFVELGDFISTVIKLNYVFNEGEANT", "length": 321 }, "evidence": [ { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" }, { "id": "FB:FBgn0032402", "url": "https://alliancegenome.org/gene/FB:FBgn0032402#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CHS4-1", "protein_name": "PI-PLC X domain-containing protein 1", "gene_name": "Plcxd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGLEPSRVGRVGEVCRSVHKNVLTVPEHTVGTEAAAPMGDQADWMSQLCPQLWDVPLHHLSIPGSHDTMTYCLNRKSRISRASSWLLHLLGRVVPFITGPVVMKWSVTQTLDVTQQLDAGVRYLDLRIAHAPEGSTRNLCFVHMMYTKALVEDTLTEIAEWLQSHPREVVILACRNFEGMTCELHDYLAGCIVNIFGDMLCPSGEVPTLRQLWAREQQVIVSYEDEATVSRYDQLWPAIPYWWGNAVKTDVLLRFLETMKGQGRPDGLFVAGINITENLCYILLHPVDSLEEMTRRSLPLMTEWVCAQQPGQSPQCTNIIAGDFVDADGFVSKVISLNCKLLSP", "length": 345 }, "evidence": [ { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NUJ7-1", "protein_name": "PI-PLC X domain-containing protein 1", "gene_name": "PLCXD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGGQVSASNSFSRLHCRNANEDWMSALCPRLWDVPLHHLSIPGSHDTMTYCLNKKSPISHEESRLLQLLNKALPCITRPVVLKWSVTQALDVTEQLDAGVRYLDLRIAHMLEGSEKNLHFVHMVYTTALVEDTLTEISEWLERHPREVVILACRNFEGLSEDLHEYLVACIKNIFGDMLCPRGEVPTLRQLWSRGQQVIVSYEDESSLRRHHELWPGVPYWWGNRVKTEALIRYLETMKSCGRPGGLFVAGINLTENLQYVLAHPSESLEKMTLPNLPRLSAWVREQCPGPGSRCTNIIAGDFIGADGFVSDVIALNQKLLWC", "length": 323 }, "evidence": [ { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VIP3-1", "protein_name": "Phosphatidylinositol-specific phospholipase C X domain-containing protein", "gene_name": "38B.13", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKDHWMRDLPSELRDLSIINLAIPGSHNSMTYGINSKSELSPDAEISIRRWHRFFPCFVRRWSKTQSSGTLDQLELGVRYFDLRIAQKDDKFYYCHGLFAMEIFEPLLEIRQFVDTHPEEVVILDLQHFYAMTVAHHQKLHKDLIQFFAHRLYSTVDGSLKDCTLNRCLEMQRSVVIIYRRCPIPLPLRFWPSYAWPTPWPNKASVKKLQSFLEDSLLSRQPQQGYVSQCLITPTGRYIAFRLFFTLKSTAKRVDKKLQPWIQEQIPGPFEPKDEPRVNVFLADFVSLKGGQFCDWVVDLNTKLLEQLAGDKELESTEGVEEEEAQG", "length": 328 }, "evidence": [ { "id": "HGNC:26462", "url": "https://alliancegenome.org/gene/HGNC:26462#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-217#orthology", "database": "AGR" }, { "id": "RGD:1563504", "url": "https://alliancegenome.org/gene/RGD:1563504#orthology", "database": "AGR" }, { "id": "MGI:3647874", "url": "https://alliancegenome.org/gene/MGI:3647874#orthology", "database": "AGR" }, { "id": "FB:FBgn0032845", "url": "https://alliancegenome.org/gene/FB:FBgn0032845#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKC3-1", "protein_name": "Phosphatidylinositol-specific phospholipase C X domain containing, isoform B", "gene_name": "PLCXD", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVGKVLRLALVLLLLASWTNEGRAQTESYENPKALKVWLTISARKRFLEVSWSNAPANKGDQLLVTREDALSFQSQLLRKHTPLAGFPSEEGSGSGDGSPSYVPNSGFTARPATKAASKEEEQEQYWVANGGATEVVAAIEPRQGLSTQWFTTGLPFDYALSRNATVQTACYGFWASYIDAQGNILAKTCLKVFPRWMNDLKSKIGEMRLRDLFIPGTHDSGSYRPNFDPLLRESLVTKYALTQDDDIRGQLMHGVRYLDIRVGYYRNSPDPFFIYHGITKQRPLQEVINQVRDFVYETNEIIIFGLKEFPVGFGKGLGVHRLLISYLRDQLKDLIAHPSLTWGASLRDIWARRQNVFLAYDHEAMVEEFPDVLFGSVEQRWGNKQTWDQLETYLRNVNDFDVSRFSSRPVSDMAELTPETWDVILDKTGGLRKMADNVNWRISQLYRNELGTNANIVSADFIRGTTLVETAIEYNARKIYM", "length": 482 }, "evidence": [ { "id": "HGNC:26462", "url": "https://alliancegenome.org/gene/HGNC:26462#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-217#orthology", "database": "AGR" }, { "id": "RGD:1563504", "url": "https://alliancegenome.org/gene/RGD:1563504#orthology", "database": "AGR" }, { "id": "MGI:3647874", "url": "https://alliancegenome.org/gene/MGI:3647874#orthology", "database": "AGR" }, { "id": "FB:FBgn0032402", "url": "https://alliancegenome.org/gene/FB:FBgn0032402#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQW3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQW3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3" } ], "pmid": "" }, { "name": "lipid catabolic process", "id": "GO:0016042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016042", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQW3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphoric diester hydrolase activity", "id": "GO:0008081", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008081", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UQW3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UQW3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UQW3" }, { "id": "SM00148", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00148" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phosphatidylinositol-specific phospholipase C X", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 195, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 217, "end_pos": 219 }, { "start_pos": 80, "end_pos": 82 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UR43-1", "uniprot_ac": "A0A8N7UR43", "uniprot_id": "A0A8N7UR43_DANRE", "mass": { "chemical_mass": 74400.0, "monoisotopic_mass": 74400.0 }, "refseq": { "ac": "XP_021331610", "name": "FAST kinase domain-containing protein 2, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331610" }, "gene_names": [ { "name": "fastkd2", "type": "recommended", "evidence": [ { "id": "A0A8N7UR43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43" } ] }, { "name": "fastkd2", "type": "synonym", "evidence": [ { "id": "XP_021331610", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331610" } ] } ], "protein_names": [ { "name": "FAST kinase domain-containing protein 2, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_021331610", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331610" }, { "id": "A0A8N7UR43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021331610", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331610" } ] } ], "disease": [ { "disease_id": "DOID:0060286", "recommended_name": { "id": "DOID:0060286", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060286", "name": "combined oxidative phosphorylation deficiency", "description": "A mitochondrial metabolism disease that is characterized by growth retardation, microcephaly, hypertonia, encephalopathy, cardiomyopathy and liver dysfunction." }, "synonyms": [ { "id": "MONDO:0012191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012191", "name": "hepatoencephalopathy due to combined oxidative phosphorylation defect type 1", "description": "Hepatoencephalopathy due to combined oxidative phosphorylation deficiency type 1 is a rare, inherited mitochondrial disorder due to a defect in mitochondrial protein synthesis characterized by intrauterine growth retardation, metabolic decompensation with recurrent vomiting, persistent severe lactic acidosis, encephalopathy, seizures, failure to thrive, severe global developmental delay, poor eye contact, severe muscular hypotonia or axial hypotonia with limb hypertonia, hepatomegaly and/or liver dysfunction and/or liver failure, leading to fatal outcome in severe cases. Neuroimaging abnormalities may include corpus callosum thinning, leukodystrophy, delayed myelination and basal ganglia involvement." }, { "id": "MONDO:0012191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012191", "name": "GFM1 combined oxidative phosphorylation deficiency", "description": "" }, { "id": "MONDO:0012191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012191", "name": "Hepatoencephalopathy due to COXPD1", "description": "" }, { "id": "MONDO:0012191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012191", "name": "combined oxidative phosphorylation deficiency caused by mutation in GFM1", "description": "" }, { "id": "MONDO:0012191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012191", "name": "combined oxidative phosphorylation deficiency type 1", "description": "" }, { "id": "MONDO:0012191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012191", "name": "hepatoencephalopathy due to combined oxidative phosphorylation defect type 1", "description": "" }, { "id": "MONDO:0012191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012191", "name": "COXPD1", "description": "" }, { "id": "MONDO:0012191", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012191", "name": "combined oxidative phosphorylation deficiency 1", "description": "" }, { "id": "MIM:609060", "resource": "MIM", "url": "https://www.omim.org/entry/609060", "name": "Combined oxidative phosphorylation deficiency 1", "description": "Combined oxidative phosphorylation deficiency 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060286", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060286" } ] }, { "disease_id": "DOID:0070424", "recommended_name": { "id": "DOID:0070424", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070424", "name": "combined oxidative phosphorylation deficiency 44", "description": "A combined oxidative phosphorylation deficiency that has_material_basis_in homozygous or compound heterozygous mutation in the FASTKD2 gene on chromosome 2q33." }, "synonyms": [ { "id": "DOID:0070424", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070424", "name": "COXPD44", "description": "" }, { "id": "MONDO:0030020", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030020", "name": "combined oxidative phosphorylation deficiency 44", "description": "" }, { "id": "MONDO:0030020", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030020", "name": "COMBINED OXIDATIVE PHOSPHORYLATION DEFICIENCY 44", "description": "" }, { "id": "MONDO:0030020", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030020", "name": "COXPD44", "description": "" }, { "id": "MONDO:0030020", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030020", "name": "combined oxidative phosphorylation deficiency 44", "description": "" }, { "id": "MIM:618855", "resource": "MIM", "url": "https://www.omim.org/entry/618855", "name": "Combined oxidative phosphorylation deficiency 44", "description": "Combined oxidative phosphorylation deficiency 44" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070424", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070424" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR43", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fastkd2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-7", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "564382", "url": "https://www.ncbi.nlm.nih.gov/gene/564382", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013584", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013584", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564382", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564382", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UR43", "url": "https://www.orthodb.org/?gene=A0A8N7UR43", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21228:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21228:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06743", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06743", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08373", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08373", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021331610", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021331610", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UR43", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UR43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-7", "url": "https://zfin.org/ZDB-GENE-090313-7", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNVYKSGLDMLRLALKSTSPWKCDSFIRTQASSCYKIISIVASPQLGRKNTHSFKQIRFYSQHSSQDAVDLQVKQTTEAFEVSDQADSTPFSAHLQKCSCPTDVLDAVKQFPASQNDLSSIFSRMRESTKKMTAEQQRCELQLMFEHPGFREVCERVVSDAWRMRCDDLAYTLLAIINLGVSQHTRIVQTLLRVVQERLNQFDNRSLSVLAAGIQQMENGNNVQALREALGLLLKDRVPEISNVVVLQNMMRAMGKNSPKELKMQLAIKTLSLADEFSPPNTQYVFLSLAAMDLNFKPLLNICSKNIAENVHEFPISRLVMVLKSCYELQYRNYSLFSSISEYMTNTFDMWSNKKVILLLLTFEDLYFRPVHLLDAFAERIIQKPDSLTLKDLLSVLKVFSMLNHDLKERKTEFLDCITEVLESYLPKMTPSELLKVNYYLALMEHFHQMLLDKLMQQETLEQLLQTDKPSIKVLRWLHTIDLCLQLDKPQLPSFTSSKPLNITVPAFEATANQEMLSAVRSIVGTHAVQDSVLEQSIYFIDCVITLPGEKVETCGLHEDCGSPECNQRIAVICAQPNSFCFGTTHPRASLVMKLRHLEKLGYQPVLVPINELNSKTEEEKIKMLRTLIFPAHESPESQKISNNSQQKEDIS", "length": 652, "header": "tr|A0A8N7UR43-1|A0A8N7UR43_DANRE Isoform 1 of FAST kinase domain-containing protein 2, mitochondrial OS=Danio rerio OX=7955 GN=fastkd2 PE=1 SV=1 CANONICAL=A0A8N7UR43-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UR43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43/entry#A0A8N7UR43-1", "sequence": { "sequence": "MNVYKSGLDMLRLALKSTSPWKCDSFIRTQASSCYKIISIVASPQLGRKNTHSFKQIRFYSQHSSQDAVDLQVKQTTEAFEVSDQADSTPFSAHLQKCSCPTDVLDAVKQFPASQNDLSSIFSRMRESTKKMTAEQQRCELQLMFEHPGFREVCERVVSDAWRMRCDDLAYTLLAIINLGVSQHTRIVQTLLRVVQERLNQFDNRSLSVLAAGIQQMENGNNVQALREALGLLLKDRVPEISNVVVLQNMMRAMGKNSPKELKMQLAIKTLSLADEFSPPNTQYVFLSLAAMDLNFKPLLNICSKNIAENVHEFPISRLVMVLKSCYELQYRNYSLFSSISEYMTNTFDMWSNKKVILLLLTFEDLYFRPVHLLDAFAERIIQKPDSLTLKDLLSVLKVFSMLNHDLKERKTEFLDCITEVLESYLPKMTPSELLKVNYYLALMEHFHQMLLDKLMQQETLEQLLQTDKPSIKVLRWLHTIDLCLQLDKPQLPSFTSSKPLNITVPAFEATANQEMLSAVRSIVGTHAVQDSVLEQSIYFIDCVITLPGEKVETCGLHEDCGSPECNQRIAVICAQPNSFCFGTTHPRASLVMKLRHLEKLGYQPVLVPINELNSKTEEEKIKMLRTLIFPAHESPESQKISNNSQQKEDIS", "length": 652, "header": "tr|A0A8N7UR43-1|A0A8N7UR43_DANRE Isoform 1 of FAST kinase domain-containing protein 2, mitochondrial OS=Danio rerio OX=7955 GN=fastkd2 PE=1 SV=1 CANONICAL=A0A8N7UR43-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:564382", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564382", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5M7V7-1", "protein_name": "FAST kinase domain-containing protein 2, mitochondrial", "gene_name": "Fastkd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNRAHTFLWGIRQFRTSIPRSRALRTYSLVFCKPEVIHSKRNPRNHLLNGFDEGLQPSVRYLFQDIFISKSVAGCTQTRGIIHAAGFKLDRILCPRRLSFDAKHSFVSDGTSDHDLMKTNFHHTSTEDVLTKKMRPTPVNYKKLAQECNSLSDVLDTFSKAPTFPGSNYFLAMWIIAKRISEDKRRFEKQLMFSHPAFNQLCEQMMREAKIMRYDHLLFSLNAIVKLGVPQNSLMVQTLLRTIQERISECDERCLSILSTALVTMEPCMNVNALRAGLRILVDQQVWNINDIFTLQTVMRCIGKDMKALKELGRFSVLNSRHMFEVLAAMDHRSVVLLNECSKIVIDNIHGCPFKVLISILQSCRDLRYQNEDLFKSIADYVATTFDIWKLKHVIFFLLSFETLGFRPPGLMDKLLEKVVQEPGSLTVKNIVSVLHVYSSLNHVHNVQNREFLEALASALTGCLHQISSESLLNAVHSFCMMNYFPLAPINQLIKENIIHELLTSGDTEKNIHKLHVLNTCLKLDESTYKCIHIPLPQLPLTASHPNEKLAEVLSRLLEGDGCFSRNVQLPHNYHIDFEIRMDTNRTQVFSFSEGDASSATNMQRVAVLCVPKSAYCLNSNHLRGLMAMKIRHLNVMGFHVILIHNWELKKLKMEDAVTFVRKKIYSDEALATTDESV", "length": 679 }, "evidence": [ { "id": "HGNC:29160", "url": "https://alliancegenome.org/gene/HGNC:29160#orthology", "database": "AGR" }, { "id": "RGD:1307883", "url": "https://alliancegenome.org/gene/RGD:1307883#orthology", "database": "AGR" }, { "id": "MGI:1922869", "url": "https://alliancegenome.org/gene/MGI:1922869#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-7#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q922E6-1", "protein_name": "FAST kinase domain-containing protein 2, mitochondrial", "gene_name": "Fastkd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSKARSLLWTIRRFSTLLPRSRALRIDPLGTCRPEVIHSKWNPRNHRLNVFDEGLQPSVRYLFQDIFISKSVDGCIQTKGISHSAVFKPDRLLCPRRLSFDAKHSFVSDGTSDHDLKKINFHHTSSEDVFTKKVRPTPVNYKKLAQECNSLSDVLDTFSKAPTFPGSNYFLAMWIIAKRISEDKRRFERQLMFSHPAFNQLCEQMMREAKIMHYDHLLFSLNAIVKLGIPQNTLMVQTLLRTIQERINECDERCLSILSTALVSMEPCMNVNALRAGLRILVDQQVWNIKHVFTLQTVMKCIGKDAPSALKKKLEMKALKELGRFSILNSQHMFEVLAAMDLRSVVLLNECSKVVIDNVHGCPFKVLISILQSCRDLRYQNEDLFKSIAEYVATTFDIWKLKQVIFFLLLFETLGFRPPGLMDKLMEKVVQEPGSLNVKNIVSILHVYSSLNHVHKIHNREFLEALASALTGCLHHISSESLLNAVHSFCMMNYFPLAPINQLIKENIINELLTSGDTEKNIHKLHVLNTCLKLDESTYKSVHIPLPQLPLSASQPNEKLAEVLSRLLEGEGRFSRNVPLPHNYHIDFEIRMDTNRTQVFSFSDVDASSATNMQRVAVLCVPKSVYCLNSCHPRGLMAMKIRHLNVMGFHVILIHNWELKKLKMEDAVTFVRKKIYSDEVLPTADTTV", "length": 689 }, "evidence": [ { "id": "HGNC:29160", "url": "https://alliancegenome.org/gene/HGNC:29160#orthology", "database": "AGR" }, { "id": "RGD:1307883", "url": "https://alliancegenome.org/gene/RGD:1307883#orthology", "database": "AGR" }, { "id": "MGI:1922869", "url": "https://alliancegenome.org/gene/MGI:1922869#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-7#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NYY8-1", "protein_name": "FAST kinase domain-containing protein 2, mitochondrial", "gene_name": "FASTKD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLTTLKPFGSVSVESKMNNKAGSFFWNLRQFSTLVSTSRTMRLCCLGLCKPKIVHSNWNILNNFHNRMQSTDIIRYLFQDAFIFKSDVGFQTKGISTLTALRIERLLYAKRLFFDSKQSLVPVDKSDDELKKVNLNHEVSNEDVLTKETKPNRISSRKLSEECNSLSDVLDAFSKAPTFPSSNYFTAMWTIAKRLSDDQKRFEKRLMFSHPAFNQLCEHMMREAKIMQYKYLLFSLHAIVKLGIPQNTILVQTLLRVTQERINECDEICLSVLSTVLEAMEPCKNVHVLRTGFRILVDQQVWKIEDVFTLQVVMKCIGKDAPIALKRKLEMKALRELDRFSVLNSQHMFEVLAAMNHRSLILLDECSKVVLDNIHGCPLRIMINILQSCKDLQYHNLDLFKGLADYVAATFDIWKFRKVLFILILFENLGFRPVGLMDLFMKRIVEDPESLNMKNILSILHTYSSLNHVYKCQNKEQFVEVMASALTGYLHTISSENLLDAVYSFCLMNYFPLAPFNQLLQKDIISELLTSDDMKNAYKLHTLDTCLKLDDTVYLRDIALSLPQLPRELPSSHTNAKVAEVLSSLLGGEGHFSKDVHLPHNYHIDFEIRMDTNRNQVLPLSDVDTTSATDIQRVAVLCVSRSAYCLGSSHPRGFLAMKMRHLNAMGFHVILVNNWEMDKLEMEDAVTFLKTKIYSVEALPVAAVNVQSTQ", "length": 710 }, "evidence": [ { "id": "HGNC:29160", "url": "https://alliancegenome.org/gene/HGNC:29160#orthology", "database": "AGR" }, { "id": "RGD:1307883", "url": "https://alliancegenome.org/gene/RGD:1307883#orthology", "database": "AGR" }, { "id": "MGI:1922869", "url": "https://alliancegenome.org/gene/MGI:1922869#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "mitochondrial RNA processing", "id": "GO:0000963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000963", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR43", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43" } ], "pmid": "" }, { "name": "regulation of mitochondrial mRNA stability", "id": "GO:0044528", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044528", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR43", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR43", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43" } ], "pmid": "" }, { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR43", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR43", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43" } ], "pmid": "" }, { "name": "ribonucleoprotein granule", "id": "GO:0035770", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035770", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UR43", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 333, "end_pos": 335, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UR43", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UR43" }, { "id": "PS51286", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51286" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RAP", "eco_id": "ECO_0000259", "start_pos": 570, "end_pos": 627, "start_aa": "Ile", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 204, "end_pos": 206 }, { "start_pos": 333, "end_pos": 335 }, { "start_pos": 502, "end_pos": 504 }, { "start_pos": 643, "end_pos": 645 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7URA4-1", "uniprot_ac": "A0A8N7URA4", "uniprot_id": "A0A8N7URA4_DANRE", "mass": { "chemical_mass": 37757.0, "monoisotopic_mass": 37757.0 }, "refseq": { "ac": "XP_695868", "name": "calcium/calmodulin-dependent protein kinase type 1B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695868" }, "gene_names": [ { "name": "pnck", "type": "recommended", "evidence": [ { "id": "A0A8N7URA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4" } ] }, { "name": "pnck", "type": "synonym", "evidence": [ { "id": "XP_695868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695868" } ] } ], "protein_names": [ { "name": "Calcium/calmodulin-dependent protein kinase type 1B", "type": "synonym", "evidence": [ { "id": "A0A8N7URA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4/entry#names_and_taxonomy" } ] }, { "name": "calcium/calmodulin-dependent protein kinase type 1B", "type": "synonym", "evidence": [ { "id": "XP_695868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695868" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_695868.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_695868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695868" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URA4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "pnck", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081105-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-127", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "567480", "url": "https://www.ncbi.nlm.nih.gov/gene/567480", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008271", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008271", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567480", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567480", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7URA4", "url": "https://www.orthodb.org/?gene=A0A8N7URA4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_695868", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695868", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7URA4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7URA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081105-127", "url": "https://zfin.org/ZDB-GENE-081105-127", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPLLRDLRKKDDINAVYELKEKLGEGSFSEVRVAQHRCTQKLVAVKCIRKRALKGKESMLENEVAVLRRINHENIVSLEETFETPTKLYLVMTLLTGGELLNRILERGSYTEKDASRVIYQVLQAVKYLHQLGVVHRDLKPENLIFETPLEDSKIVISDFGLSKMEEQGALSTACGTPAYVAPELLQQKTYGKEVDLWAIGVITFILLCGYPPFYDDNDTQLYKLIIKAEYEFDSPYWNDISDSAKDFIVHLLQKDPAKRFNCEQASQHPWISGGAALDRNIHGSVSAQIQKNFAKSHWKRAFNATIIVHHLTKKAHPGEDDEGNQSTSIGNI", "length": 333, "header": "tr|A0A8N7URA4-1|A0A8N7URA4_DANRE Isoform 1 of Calcium/calmodulin-dependent protein kinase type 1B OS=Danio rerio OX=7955 GN=pnck PE=3 SV=1 CANONICAL=A0A8N7URA4-1" }, "isoforms": [ { "isoform_ac": "A0A8N7URA4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4/entry#A0A8N7URA4-1", "sequence": { "sequence": "MPLLRDLRKKDDINAVYELKEKLGEGSFSEVRVAQHRCTQKLVAVKCIRKRALKGKESMLENEVAVLRRINHENIVSLEETFETPTKLYLVMTLLTGGELLNRILERGSYTEKDASRVIYQVLQAVKYLHQLGVVHRDLKPENLIFETPLEDSKIVISDFGLSKMEEQGALSTACGTPAYVAPELLQQKTYGKEVDLWAIGVITFILLCGYPPFYDDNDTQLYKLIIKAEYEFDSPYWNDISDSAKDFIVHLLQKDPAKRFNCEQASQHPWISGGAALDRNIHGSVSAQIQKNFAKSHWKRAFNATIIVHHLTKKAHPGEDDEGNQSTSIGNI", "length": 333, "header": "tr|A0A8N7URA4-1|A0A8N7URA4_DANRE Isoform 1 of Calcium/calmodulin-dependent protein kinase type 1B OS=Danio rerio OX=7955 GN=pnck PE=3 SV=1 CANONICAL=A0A8N7URA4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:567480", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567480", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AUH0-1", "protein_name": "calcium/calmodulin-dependent protein kinase", "gene_name": "Camk1d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALSKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRRLQLGSSLDSSNASVSSNLSLASQKDCLAPSTLCSFLSSSSGVAGVGAERRPRPTTVTTGHTGSK", "length": 385 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1RRA7-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type IV", "gene_name": "si:ch73-60h1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPTSRSDARPVEYWVDGSRRDATVEDFYNMGPELGRGATSVVLRCEEKQTEKPYAVKVLKKTIDKKIVRTEIGVLLRLSHPNIIRLKEIFETETEIFLILELVTGGELFDRIVERGYYSERDAAHVIKQILEAVAYLHENGVVHRDLKPENLLYADLSIDAPLKIADFGLSKIIDEQVTMKTVCGTPGYCAPEILRGNAYGPEVDMWSVGVILYILLCGFEPFFDQRGDQYMYSRILNCDYEFVSPWWDEVSLNAKDLVNKLIVLDPHKRLTVKQALEHPWVLGKAARFSHMDTTQRKLQEFNARRKLKAAMKAVVATSRMHEGSRRRTDSCEMPNTDKTSCQSSIQKENTTNSSREPISMKEGSEQVADGALGPSSSTPQTTPKSKPFTQSGPVPTRPPLIAEGHRQTSVIPKAPVVRPREPKKSFSVEPGGKHEVS", "length": 438 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3ANJ4-1", "protein_name": "CaM kinase-like vesicle-associated protein", "gene_name": "camkvl", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRVDAVMPFGCLALRDGRTYNSLSDITDKYEIGQVLKAKEFCELCLVKERQTDKVYVCKKFLKKDGRKVRKAAKNEIMILKMVKHPNILQLIDAFETRKEFFIIQELATGGDVFDWILDQGNYTERDAANVIRQVLEAVAYLHSLNIVHRNLKLENLMYYRESNHNKVVLRDFYLSRFENGSITEPCGTPEYLAPEVVARHRYGRPVDCWAVGVIMYILLSGNPPFYDETEEENTDMHNRIIFCRIVGGEFEFDSPYWDDISPAAKELVCRFMEVDQMLRITAQDALTHEWIAGNGASEKNLKEGVCAQFEKNFAKAKWRKAIRVTTFMQRLRATDIGSSDGAVEGQAEGVKADGLDGKGIQTDSGGVSAGSVSHEVSVESRPTENQEAGQTKVEEKETETVGQSNSSLKIQAEEPLNKKETTEGTSEIKDKPTTGANQKAASVQPIKTSDSRENSIPVEPEATTLGSVEKKSPFHDTPNRRKIAANLSMDHSSCSEAKTATLSTGNEPPLQSEDKKDTVHDMTASSWCQTQLPEAVAERSAEVGAPSEVNPKSKELKKGRADKGSQSVKNIQSVYAGLGSSSLGQDQTVFVQELQEMVHGASGYGSPYCPTYSVGQYGGLDPGSAASADWQMDCVIEQIEKQMAAVLEKIEGDMPSLLEQISDHPETLPRAKSASSSPSPRPRSYHHSTPPPLPTTPRPVMPSLPHLTIPPPSYPPPSPPSQIQGHSHPAPEESTSDGQKSTKRSGQSPRGSVSGKGL", "length": 759 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PSZ5-1", "protein_name": "Calcium/calmodulin-dependent protein kinase IGb isoform X1", "gene_name": "camk1gb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVSLRSAQFPLPSHVILCHCCPCLRLDSFCKRQKSCWSCYRPEEIPVEAHAEMGRKEGEYEWKKSTDNIQDVFDFMDVLGSGAFSEVFMVKERKTGKLFAMKCVKKKNKRDINLENEIAVLRKIKHENVVCLEDFYESRTHYYLVMQLVSGGELFDRILDRGMYSEMDASSVIRQVLEAVSYLHNNGIVHRDLKPENLLYYSPDENSKIMISDFGLSKMEDNGVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETETRLFSKIMKGQYEFDSPFWDDISDSAKDFIRNMMQKNPKMRFNTEQALRHPWIIGKTARSQDIYHSVSEQMQKNFAKSKWKQAFNATVAINHMKKLQQAHSEACVRLKDSPRDVPEIKVIASSTPESVRKKLLSETPEPNGSMNVPCGSTEAKSQYHPMRVSHSETTHVGTLTIAEKGKHVYHSEPADLNGYAKRSSNRPGQNLQTGVCSVM", "length": 486 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UVK7-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1 isoform X1", "gene_name": "camk1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPLGEDENGWKKKTTDIKENYDFKEVLGTGAFSEVFLAEEKKTQRLVAIKCIPKKALEGKENSIENEIAVLHRIKHENIVSLEDIFESQSHLYLVMQLVSGGELFDRIVEKGFYTERDASKLIRQILDAVKYLHDMGIVHRDLKPENLLYYSMEEDSNIMISDFGLSKIEDSGSVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVISYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFISHLMEKDPSLRYTCEQALLHPWISGDTALDKNIHESVSAQIKKNFAKSKWKQAFNATAVVRHMRRLQLSTSLEGPSQITSTSPYRHLLLPAKELDQRDEEEEEEEEEEENGSPSVDGRRGSADRDSLRSCAYCCRPTSRI", "length": 394 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JVK9-1", "protein_name": "CaM kinase-like vesicle-associated protein", "gene_name": "camkva", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMRAGAAMPFGCLTLGEKKDYNSPSEVTDKYDLGQVVKSEEFCEIFRAKDKNTLKMYTCKKFLKKDGRKVRKAAKNEILILKMVKHHNILQLVDVFETRKEYFLFLELATGREVFDWILDQGYYSERDTSNVIRQVLEAVAYLHSLRIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYDETDDDDYDNHDKNLFRKILSGDYEFDSPYWDDISDSAKSLVACLMDVDQDQRLTAQEAINHEWISGNAASDKNIKDGVCAQIEKNFAKAKWKKAVRVTTMMKRLRAPDQSDSGASSPALGASGGPVTPSTTPVPLAATPEASASTRCNGEMLTSQQRSGDNREE", "length": 393 }, "evidence": [ { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4ABY1-1", "protein_name": "Serine/threonine-protein kinase H1", "gene_name": "Pskh1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSATKNDVYKHFITEVDSVGPLKAGFPATSQYAPPCPGAPTTGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSSQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG", "length": 424 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F1H0-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1 isoform X2", "gene_name": "camk1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPLGEDGPSWKKKTANIKDIYDFKEVLGTGAFSEVMLAEEKRTRKLVAVKCIAKKALEGKENSIENEIAVLHKIKHANIVSLEDIFESKSHLYLVMQLVSGGELFDRIVEKGFYTEKDASKLIQQILDAVKYLHDMGIVHRDLKPENLLYYSMDEESKIMISDFGLSKIEGSGSVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILRAEYEFDSPYWDDISDSAKDFIVHLMEKDPNQRYTCEQALQHPWIAGDTALDKNIHESVSAQIKKNFAKSKWKQAFNATAVVRHMRRLQLGTSQEGPPQNTLPSPCHGHLLLPEGDEDDSVRENSGCSEGVSDGNDIQNCSYHLHPTSRV", "length": 382 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O70150-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1B", "gene_name": "Pnck", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQHLWISGDAALDRDILGSVSEQIQKNFARTHWKRAFNATSFLRHIRKLGQSPEGEEASRQGMTRHSHPGLGTSQSPKW", "length": 343 }, "evidence": [ { "id": "MGI:1347357", "url": "https://alliancegenome.org/gene/MGI:1347357#orthology", "database": "AGR" }, { "id": "HGNC:13415", "url": "https://alliancegenome.org/gene/HGNC:13415#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081105-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-127#orthology", "database": "AGR" }, { "id": "RGD:69249", "url": "https://alliancegenome.org/gene/RGD:69249#orthology", "database": "AGR" }, { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08414-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type IV", "gene_name": "Camk4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKVTVPSCPSSPCSSVTASTENLVPDYWIDGSNRDPLGDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDARDAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHTSIQENHKASSDPPSTQDAKDSTDLLGKKMQEEDQEEDQVEAEASADEMRKLQSEEVEKDAGVKEEETSSMVPQDPEDELETDDPEMKRDSEEKLKSVEEEMDPMTEEEAPDAGLGVPQQDAIQPEY", "length": 469 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P11801-1", "protein_name": "Serine/threonine-protein kinase H1", "gene_name": "PSKH1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKSDVYKHFITEVDSVGPVKAGFPAASQYAHPCPGPPTAGHTEPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYSGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSAQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG", "length": 424 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13234-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type IV", "gene_name": "Camk4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKVTVPSCPSSPCSSVTSSTENLVPDYWIDGSKRDPLSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVKKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHTNIQESNKASSEAQPAQDGKDKTDPLENKMQAGDHEAAKAAADETMKLQSEEVEEEEGVKEEEEEEEEEEETSRMVPQEPEDRLETDDQEMKRNSEETLKSVEEEMDPKAEEEAAAVGLGVPPQQDAILPEY", "length": 474 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P22517-1", "protein_name": "Calcium/calmodulin-dependent protein kinase II", "gene_name": "CMK2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPKESEVINSEFHVDVQDPERLNGHPVAKFINKLSGQPESYVNRTNYIFGRTLGAGSFGVVRQARKLSTNEDVAIKILLKKALQGNNVQLQMLYEELSILQKLSHPNIVSFKDWFESKDKFYIVTQLATGGELFDRILSRGKFTEVDAVEIIVQILGAVEYMHSKNVVHRDLKPENVLYVDKSENSPLVIADFGIAKQLKGEEDLIYKAAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSPFIAESVEGFMEECTASRYPVTFHMPYWDNISIDVKRFILKALRLNPADRPTATELLDDPWITSKRVETSNILPDVKKGFSLRKKLRDAIEIVKLNNRIKRLRNMYSLGDDGDNDIEENSLNESLLDGVTHSLDDLRLQSQKKGGELTEEQMKLKSALTKDAFVQIVKAATKNKHKVLAGEEEDDSKKTLHDDRESKSED", "length": 447 }, "evidence": [ { "id": "MGI:1347357", "url": "https://alliancegenome.org/gene/MGI:1347357#orthology", "database": "AGR" }, { "id": "HGNC:13415", "url": "https://alliancegenome.org/gene/HGNC:13415#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081105-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-127#orthology", "database": "AGR" }, { "id": "RGD:69249", "url": "https://alliancegenome.org/gene/RGD:69249#orthology", "database": "AGR" }, { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P27466-1", "protein_name": "Calcium/calmodulin-dependent protein kinase I", "gene_name": "CMK1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDDKVSEKESSPKQTEEDSEGKMAHVQPASYVNKKKYVFGKTLGAGTFGVVRQAKNTETGEDVAVKILIKKALKGNKVQLEALYDELDILQRLHHPNIVAFKDWFESKDKFYIITQLAKGGELFDRILKKGKFTEEDAVRILVEILSAVKYMHSQNIVHRDLKPENLLYIDKSDESPLVVADFGIAKRLKSDEELLYKPAGSLGYVAPEVLTQDGHGKPCDIWSIGVITYTLLCGYSAFRAERVQDFLDECTTGEYPVKFHRPYWDSVSNKAKQFILKALNLDPSKRPTAAELLEDPWIICTELKTHNLLPGLKEGLDARQKFRNSVERVRLNMKIQKLRDLYLEQTESDSDFDEGSQANGSVPPLKATDTSQLSKKLSEEEQSKLKSELTSKAFAQLVNTVLAEKEKFLNINRVCSSDSDLPGSDIKSLDEAKEKPEGKDTKTEE", "length": 446 }, "evidence": [ { "id": "MGI:1347357", "url": "https://alliancegenome.org/gene/MGI:1347357#orthology", "database": "AGR" }, { "id": "HGNC:13415", "url": "https://alliancegenome.org/gene/HGNC:13415#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081105-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-127#orthology", "database": "AGR" }, { "id": "RGD:69249", "url": "https://alliancegenome.org/gene/RGD:69249#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q14012-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1", "gene_name": "CAMK1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKEALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQEGQGQTASHGELLTPVAGGPAAGCCCRDCCVEPGTELSPTLPHQL", "length": 370 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q16566-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type IV", "gene_name": "CAMK4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKVTVPSCSASSCSSVTASAAPGTASLVPDYWIDGSNRDALSDFFEVESELGRGATSIVYRCKQKGTQKPYALKVLKKTVDKKIVRTEIGVLLRLSHPNIIKLKEIFETPTEISLVLELVTGGELFDRIVEKGYYSERDAADAVKQILEAVAYLHENGIVHRDLKPENLLYATPAPDAPLKIADFGLSKIVEHQVLMKTVCGTPGYCAPEILRGCAYGPEVDMWSVGIITYILLCGFEPFYDERGDQFMFRRILNCEYYFISPWWDEVSLNAKDLVRKLIVLDPKKRLTTFQALQHPWVTGKAANFVHMDTAQKKLQEFNARRKLKAAVKAVVASSRLGSASSSHGSIQESHKASRDPSPIQDGNEDMKAIPEGEKIQGDGAQAAVKGAQAELMKVQALEKVKGADINAEEAPKMVPKAVEDGIKVADLELEEGLAEEKLKTVEEAAAPREGQGSSAVGFEVPQQDVILPEY", "length": 473 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3UHL1-1", "protein_name": "CaM kinase-like vesicle-associated protein", "gene_name": "Camkv", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPFGCVTLGDKKNYNQPSEVTDRYDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKFQKRDGRKVRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSGTAATQSASDAATPGAAGGAIAAAAAAAAAGGAASASGASATAATEGGAGCAAKSDDIASADRSATPATDGSATPATDGSVTPATDGSITPATDGSVTPATDRSATPATDGRATPATEESTVPATQSSALPAAKAAATPEPAVAQPDSTALEGATGQAPPSSKGEEATGCAQESQRVETS", "length": 512 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q501V0-1", "protein_name": "Serine/threonine-protein kinase H1 homolog", "gene_name": "pskh1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCRTSKVLPEPPGDVQLDLVKKVEPHQTDVYKNFIKYDGGGEKTGSPSPQGQSQAVAKVSQSPPPANDQPEPADSHRKKVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRSTRQPYAIKMIETRYREGREVCESELCVLRRVRHTNIIQLMEVFETAERVYMVMELATGGELFDRIITRGSFTERDATRVLQMVLDGVKYLHTLGITHRDLKPENLLYYHPGADSKIMITDFGLASTRKKGDECLMKTTCGTPEYIAPEILVRKPYTNAVDMWALGVISYILLSGTMPFEDDNRMRLYRQILKGKYSFSGEPWPSVSNLAKDFIDRVLTVDPNERLSAGQALKHPWIVSMAASSSMKNLHRSISQNLLKRASSRCHSTKSSQSTRSSRSTKSSKARRLREKELRELNRRYQQQCNG", "length": 422 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q63092-1", "protein_name": "CaM kinase-like vesicle-associated protein", "gene_name": "Camkv", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPFGCVTLGDKKNYNQPSEVTDRYDLGQVVKTEEFCEIFRAKDKTTGKLHTCKKFQKRDGRKVRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSGTAATSDAATPGAAGGAVAAAAGGAAPASGASATVGTGGDAGCAAKSDDMASADRSATPATDGSATPATDGSVTPATDGSITPATDGSVTPATDRSATPATDGRATPATEESTVPAAQSSAAPAAKAAATPEPAVAQPDSTALEGATGQAPPSSKGEEATGCAQESQRVETS", "length": 504 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q63450-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1", "gene_name": "Camk1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQEGQGQTASHGELLTPTAGGPAAGCCCRDCCVEPGSELPPAPPPSSRAMD", "length": 374 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P2M8-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1B", "gene_name": "PNCK", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLLKKHTEDISSVYEIRERLGSGAFSEVVLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALRHLWISGDTAFDRDILGSVSEQIRKNFARTHWKRAFNATSFLRHIRKLGQIPEGEGASEQGMARHSHSGLRAGQPPKW", "length": 343 }, "evidence": [ { "id": "MGI:1347357", "url": "https://alliancegenome.org/gene/MGI:1347357#orthology", "database": "AGR" }, { "id": "HGNC:13415", "url": "https://alliancegenome.org/gene/HGNC:13415#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081105-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-127#orthology", "database": "AGR" }, { "id": "RGD:69249", "url": "https://alliancegenome.org/gene/RGD:69249#orthology", "database": "AGR" }, { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7SY49-1", "protein_name": "CaM kinase-like vesicle-associated protein", "gene_name": "camkv", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPFGCLKPGEKKDYNSPTEITDKYDLGQIVKSEEFCEIFRAKDKNTLKMYTCKKFLKKDGRKVRKAAKNEIVILKMVKHPNILQLVDVYETRKEYYLFLELATGREVFDWILDQGYYSERDTSNVIRQVMEAVAYLHSLKIVHRNLKLENLVYYNRLKHSKIVISDFHLAKLENGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWALGVIMYILLSGNPPFYDEADDDDYENHDKNLFRKILAGDYEFDSPYWDEISDSAKNLVSRLMEVDQDQRLTAQEAINHEWISGNAASDKNIKENVCAQIEKNFAKAKWKKAVRVTTMMKRLRAPENQTAAATAPAAEAAAASPSEADPAAGAQETPQAASEASTAPSSTAESLSASIEVPAVEPANAEAASAAVQPPAEPVVHVPEPEQPVPTSRCNGEASALDTVEEQSG", "length": 436 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7TNJ7-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1G", "gene_name": "Camk1g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRKEEEDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLENEIAVLKRIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALRHPWIDGNTALHRDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNLHSPSVRQEVENRPPVSPAPEVSRPGSHDSSITEAPILDPSTPLPALTRLPCSHSSRPSAPGGRSLNCLVNGSLRISSSLVPMQQGPLATGPCGCCSSCLNIGNKGKSSYCSEPTLFRKANKKQNFKSEVMVPVKAGGSTHCRAGQTGVCLIM", "length": 476 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BW96-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1D", "gene_name": "Camk1d", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALSKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRRLQLGSSLDSSNASVSSNLSLASQKDCLAPSTLCSFLSSSSGVAGVGAERRPRPTTVTTGHTGSK", "length": 385 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IU85-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1D", "gene_name": "CAMK1D", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARENGESSSSWKKQAEDIKKIFEFKETLGTGAFSEVVLAEEKATGKLFAVKCIPKKALKGKESSIENEIAVLRKIKHENIVALEDIYESPNHLYLVMQLVSGGELFDRIVEKGFYTEKDASTLIRQVLDAVYYLHRMGIVHRDLKPENLLYYSQDEESKIMISDFGLSKMEGKGDVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDSKLFEQILKAEYEFDSPYWDDISDSAKDFIRNLMEKDPNKRYTCEQAARHPWIAGDTALNKNIHESVSAQIRKNFAKSKWRQAFNATAVVRHMRKLHLGSSLDSSNASVSSSLSLASQKDCLAPSTLCSFISSSSGVSGVGAERRPRPTTVTAVHSGSK", "length": 385 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NCB2-1", "protein_name": "CaM kinase-like vesicle-associated protein", "gene_name": "CAMKV", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPFGCVTLGDKKNYNQPSEVTDRYDLGQVIKTEEFCEIFRAKDKTTGKLHTCKKFQKRDGRKVRKAAKNEIGILKMVKHPNILQLVDVFVTRKEYFIFLELATGREVFDWILDQGYYSERDTSNVVRQVLEAVAYLHSLKIVHRNLKLENLVYYNRLKNSKIVISDFHLAKLENGLIKEPCGTPEYLAPEVVGRQRYGRPVDCWAIGVIMYILLSGNPPFYEEVEEDDYENHDKNLFRKILAGDYEFDSPYWDDISQAAKDLVTRLMEVEQDQRITAEEAISHEWISGNAASDKNIKDGVCAQIEKNFARAKWKKAVRVTTLMKRLRAPEQSSTAAAQSASATDTATPGAAGGATAAAASGATSAPEGDAARAAKSDNVAPADRSATPATDGSATPATDGSVTPATDGSITPATDGSVTPATDRSATPATDGRATPATEESTVPTTQSSAMLATKAAATPEPAMAQPDSTAPEGATGQAPPSSKGEEAAGYAQESQREEAS", "length": 501 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91VB2-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1G", "gene_name": "Camk1g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRKEEEDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRVTGKLFALKCIKKSPAFRDSSLENEIAVLKRIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGVMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALRHPWIDGNTALHRDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNLHSPSVRQEVENRPPVSPAPEVSRPDSHDSSITEAPILDPSTPLPALTRLPCSHSSRPSAPSGGRSLNCLVNGSLRISSSLVPMQQGPLATGPCGCCSSCLNIGNKGKSSYCSEPTLFRKANKKQNFKSEVMVPVKAGGSTHCRGGQTGVCLVM", "length": 477 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91YA2-1", "protein_name": "Serine/threonine-protein kinase H1", "gene_name": "Pskh1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCGTSKVLPEPPKDVQLDLVKKVEPFSGTKNDVYKHFITEVDSVGPLKAGFPATSQYAPPCPGVPNTGHTAPPSEPPRRARVAKYRAKFDPRVTAKYDIKALIGRGSFSRVVRVEHRATRQPYAIKMIETKYREGREVCESELRVLRRVRHANIIQLVEVFETQERVYMVMELATGGELFDRIIAKGSFTERDATRVLQMVLDGVRYLHALGITHRDLKPENLLYYHPGTDSKIIITDFGLASARKKGDDCLMKTTCGTPEYIAPEVLVRKPYTNSVDMWALGVIAYILLSGTMPFEDDNRTRLYRQILRGKYSYLGEPWPSVSNLAKDFIDRLLTVDPGARMTALQALRHPWVVSMAASSSMKNLHRSISQNLLKRASSRCQSTKSSQSTRSSRSTRSNKSRRVRERELRELNLRYQQQYNG", "length": 424 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91YS8-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1", "gene_name": "Camk1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGAVEGPRWKQAEDIRDIYDFRDVLGTGAFSEVILAEDKRTQKLVAIKCIAKKALEGKEGSMENEIAVLHKIKHPNIVALDDIYESGGHLYLIMQLVSGGELFDRIVEKGFYTERDASRLIFQVLDAVKYLHDLGIVHRDLKPENLLYYSLDEDSKIMISDFGLSKMEDPGSVLSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVIAYILLCGYPPFYDENDAKLFEQILKAEYEFDSPYWDDISDSAKDFIRHLMEKDPEKRFTCEQALQHPWIAGDTALDKNIHQSVSEQIKKNFAKSKWKQAFNATAVVRHMRKLQLGTSQEGQGQTGSHGELLTPTAGGPAAGCCCRDCCVEPGSELPPAPPPSSRAMD", "length": 374 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96NX5-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1G", "gene_name": "CAMK1G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRKEEDDCSSWKKQTTNIRKTFIFMEVLGSGAFSEVFLVKQRLTGKLFALKCIKKSPAFRDSSLENEIAVLKKIKHENIVTLEDIYESTTHYYLVMQLVSGGELFDRILERGVYTEKDASLVIQQVLSAVKYLHENGIVHRDLKPENLLYLTPEENSKIMITDFGLSKMEQNGIMSTACGTPGYVAPEVLAQKPYSKAVDCWSIGVITYILLCGYPPFYEETESKLFEKIKEGYYEFESPFWDDISESAKDFICHLLEKDPNERYTCEKALSHPWIDGNTALHRDIYPSVSLQIQKNFAKSKWRQAFNAAAVVHHMRKLHMNLHSPGVRPEVENRPPETQASETSRPSSPEITITEAPVLDHSVALPALTQLPCQHGRRPTAPGGRSLNCLVNGSLHISSSLVPMHQGSLAAGPCGCCSSCLNIGSKGKSSYCSEPTLLKKANKKQNFKSEVMVPVKASGSSHCRAGQTGVCLIM", "length": 476 }, "evidence": [ { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9QYK9-1", "protein_name": "Calcium/calmodulin-dependent protein kinase type 1B", "gene_name": "Pnck", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLKKQTEDISSVYEIREKLGSGAFSEVMLAQERGSAHLVALKCIPKKALRGKEALVENEIAVLRRISHPNIVALEDVHESPSHLYLAMELVTGGELFDRIMERGSYTEKDASHLVGQVLGAVSYLHSLGIVHRDLKPENLLYATPFEDSKIMVSDFGLSKIQAGNMLGTACGTPGYVAPELLEQKPYGKAVDVWALGVISYILLCGYPPFYDESDPELFSQILRASYEFDSPFWDDISESAKDFIRHLLERDPQKRFTCQQALQHLWISGDAAFDRDILGSVSEQIQKNFARTHWKRAFNATSFLRHIRKLGQSPEGEEASRQCMTRHSHPGLGTSQSPKW", "length": 343 }, "evidence": [ { "id": "MGI:1347357", "url": "https://alliancegenome.org/gene/MGI:1347357#orthology", "database": "AGR" }, { "id": "HGNC:13415", "url": "https://alliancegenome.org/gene/HGNC:13415#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081105-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-127#orthology", "database": "AGR" }, { "id": "RGD:69249", "url": "https://alliancegenome.org/gene/RGD:69249#orthology", "database": "AGR" }, { "id": "SGD:S000005376", "url": "https://alliancegenome.org/gene/SGD:S000005376#orthology", "database": "AGR" }, { "id": "SGD:S000001910", "url": "https://alliancegenome.org/gene/SGD:S000001910#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "calmodulin binding", "id": "GO:0005516", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005516", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URA4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URA4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4" } ], "pmid": "" }, { "name": "calcium/calmodulin-dependent protein kinase activity", "id": "GO:0004683", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004683", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URA4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URA4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URA4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 325, "end_pos": 327, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7URA4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URA4" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 272, "start_aa": "Tyr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 }, { "start_pos": 304, "end_pos": 306 }, { "start_pos": 325, "end_pos": 327 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7URE1-1", "uniprot_ac": "A0A8N7URE1", "uniprot_id": "A0A8N7URE1_DANRE", "mass": { "chemical_mass": 51647.0, "monoisotopic_mass": 51647.0 }, "refseq": { "ac": "XP_698005", "name": "photoreceptor ankyrin repeat protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698005" }, "gene_names": [ { "name": "ankrd33ab", "type": "recommended", "evidence": [ { "id": "A0A8N7URE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URE1" } ] }, { "name": "ankrd33ab", "type": "synonym", "evidence": [ { "id": "XP_698005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698005" } ] } ], "protein_names": [ { "name": "Photoreceptor ankyrin repeat protein", "type": "synonym", "evidence": [ { "id": "A0A8N7URE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URE1/entry#names_and_taxonomy" } ] }, { "name": "photoreceptor ankyrin repeat protein", "type": "synonym", "evidence": [ { "id": "XP_698005", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698005" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_698005.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_698005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698005" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URE1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URE1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ankrd33ab", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URE1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100729-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100729-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7URE1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7URE1", "database": "AlphaFoldDB", "categories": [] }, { "id": "569518", "url": "https://www.ncbi.nlm.nih.gov/gene/569518", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569518", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569518", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173:SF84", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173:SF84", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_698005", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698005", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7URE1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7URE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100729-1", "url": "https://zfin.org/ZDB-GENE-100729-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAAVQSSGFEDPHLGSCPDGDEISLLDEDTDSGSLLSEDSVLPEYELEDGKKGTANTLYEACVQNDPEALKRILERGVTCDEVMEVDINGWNGLMVAAYKGFLQIVYELHGCPHLNINHQDNDGNTALMIAAQAGHVSICNYIMNYFPGADTEIRDNRGFTALIKAAIQGRNDVVAALIMHGADVNAVDSNRGKCARDWALKTGRFDTLKRLRHLALHPTAEQFCDTYVPEWPNLKVLVSKATANRSAGQKLTHHLKNRFGFSFPRDPVENGVMDHMVRMTTSLHSPLIATATRPLCPSSPPQMGKRRLAVAELMQKHSEKLLEESSLCHRNSSISSVSPSFHSAEFVSMTCCPDTERRGSVLSIGMRTFIPRSVASRRNSIFPSGCIPQIKVTKSSEPTPKKEKKNKKDKGYLEPPKWKYKEAKEEKKKEKKALKEKEKEEKDKEKKSKDKEKRKKNKYTD", "length": 462, "header": "tr|A0A8N7URE1-1|A0A8N7URE1_DANRE Isoform 1 of Photoreceptor ankyrin repeat protein OS=Danio rerio OX=7955 GN=ankrd33ab PE=4 SV=2 CANONICAL=A0A8N7URE1-1" }, "isoforms": [ { "isoform_ac": "A0A8N7URE1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URE1/entry#A0A8N7URE1-1", "sequence": { "sequence": "MAAVQSSGFEDPHLGSCPDGDEISLLDEDTDSGSLLSEDSVLPEYELEDGKKGTANTLYEACVQNDPEALKRILERGVTCDEVMEVDINGWNGLMVAAYKGFLQIVYELHGCPHLNINHQDNDGNTALMIAAQAGHVSICNYIMNYFPGADTEIRDNRGFTALIKAAIQGRNDVVAALIMHGADVNAVDSNRGKCARDWALKTGRFDTLKRLRHLALHPTAEQFCDTYVPEWPNLKVLVSKATANRSAGQKLTHHLKNRFGFSFPRDPVENGVMDHMVRMTTSLHSPLIATATRPLCPSSPPQMGKRRLAVAELMQKHSEKLLEESSLCHRNSSISSVSPSFHSAEFVSMTCCPDTERRGSVLSIGMRTFIPRSVASRRNSIFPSGCIPQIKVTKSSEPTPKKEKKNKKDKGYLEPPKWKYKEAKEEKKKEKKALKEKEKEEKDKEKKSKDKEKRKKNKYTD", "length": 462, "header": "tr|A0A8N7URE1-1|A0A8N7URE1_DANRE Isoform 1 of Photoreceptor ankyrin repeat protein OS=Danio rerio OX=7955 GN=ankrd33ab PE=4 SV=2 CANONICAL=A0A8N7URE1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:569518", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569518", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7UVN7-1", "protein_name": "Photoreceptor ankyrin repeat protein", "gene_name": "ankrd33aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGVKVAVQEDPDLGSGPDEDASELSVSENDSDSGSVLSDDSVLPNYEREDASGGPANTLYQACAKNNAAALRRVLERGVTVDEVMELDINGRNGLMLAVSKGFVDIVYGLNQCPFLDINHQDNDGNTALMIAAQAGFVTILTYIINFFPGLDMELRDNRGFTALLKAVMQGSNDCVASLLMAGANLHVVDATRGKDIREWALKTGRFETLHRLRRLNSRPQAEQFCEKYILEWPDLKELVAKATATKSTGQKVAHRLKSTFTFNFPHDPQDNGIMDHMVRMTTSIHSPLVVTGCRPLCPSSPPEVGKRRLAVPELMEMHSGKKLEEHTIRHSNGSISVASTSGSSVSLASCCSESERRGSVLSMASNGVRRFVPRSMARRNSVFPAGCVPQIKVTKSGEPTPKKEKKSKRNKGYLEPPIWKYKEAKEEKKKEKKKEEQEKLEKGAKKKSKK", "length": 452 }, "evidence": [ { "id": "MGI:2443398", "url": "https://alliancegenome.org/gene/MGI:2443398#orthology", "database": "AGR" }, { "id": "HGNC:13788", "url": "https://alliancegenome.org/gene/HGNC:13788#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0R7C6-1", "protein_name": "Ankyrin repeat domain 33", "gene_name": "Ankrd33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEAPPCPGGKTPSPGCGLKTLYWACVHNDLAELQARLDVGVSPDEASQVDGNGRTGLMVACYHGYGSIVALLSGCPFLDVNQQDKDGNTALMLAAQAGHVPLVTLLLNYFAGLDLERRDQRGLTALMKAAIRDRSECVVALLMAGADLSSVDPVRGKTALEWAVLTDSFDTVRKIRQLLRRPQAEQLSLHYQPEWPALAQLVAQAQDQAAPSLLERLQATLNLSFAQFPQEGGVLDHLVTVTTSLASPFLTTACHTLCPDHPPTLGIRGKSVPELLGTAPPPPPAPHPPQEVPVPQAFAPYQSPQSMLSQWLQSRESTSLRSQVPKILLSKAPSPAAQYELILRPPGKQSLTLPIWRFQEKKKKEEEEPRGGRLGQAGGK", "length": 381 }, "evidence": [ { "id": "MGI:2443398", "url": "https://alliancegenome.org/gene/MGI:2443398#orthology", "database": "AGR" }, { "id": "HGNC:13788", "url": "https://alliancegenome.org/gene/HGNC:13788#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z3H0-2", "protein_name": "Photoreceptor ankyrin repeat protein", "gene_name": "ANKRD33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVQPSVTCVASWGGIVHLEAFGDPVIVLRGAWAVPRVDCLIDTLRTPNASCMRKGTHLLVPCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQLLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVLDHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPLVPQSPPGSPQRSPWVFVPYQSPQGILSKCLQWLQPRDSTSPRPQVPKILLSKASSSSHQCQPKPSPSGHQSLALPLWRYQELRIEKRKQEEEARMAQK", "length": 452 }, "evidence": [ { "id": "MGI:2443398", "url": "https://alliancegenome.org/gene/MGI:2443398#orthology", "database": "AGR" }, { "id": "HGNC:13788", "url": "https://alliancegenome.org/gene/HGNC:13788#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100729-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100729-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BXP5-1", "protein_name": "Photoreceptor ankyrin repeat protein", "gene_name": "Ankrd33", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEALPFPSNKTSTPECNLKTLYWACVHNDLAELQARLDAGVSPEEASQVDSNGRTGLMVACYHGFGSIVALLSCCPFLDVNQQDKDGNTALMLAAQAGHMSLVTLLLNYFAGLDLERRDQRGLTALMKAAIQDRSECVVALLMAGADLSSVDPVRGKTALEWAVLTDSFDTAQKIRQLLRRPQAEQLSLHYQPEWPALAQLVAQAQAQAQAPAAPSLLERLQATLSLSFAQSPQEGGVLDHLVTVTTSLASPFLSTACHTLCPDHPPKLGTRGKSVPELLGTAPPPPPEPHPPQQVPVPQVFAPNQSPQSMFSQWLQSRDSTRSQVPKILLSKAPSPSARYELTLRPQGQQSLAPPVWRFQERKKKEEETEPRGGGLGQAGGSK", "length": 385 }, "evidence": [ { "id": "MGI:2443398", "url": "https://alliancegenome.org/gene/MGI:2443398#orthology", "database": "AGR" }, { "id": "HGNC:13788", "url": "https://alliancegenome.org/gene/HGNC:13788#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100729-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100729-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URE1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URE1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 245, "end_pos": 247, "annotation": "n_glycosylation_sequon" }, { "start_pos": 332, "end_pos": 334, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 245, "end_pos": 247 }, { "start_pos": 332, "end_pos": 334 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7URF7-1", "uniprot_ac": "A0A8N7URF7", "uniprot_id": "A0A8N7URF7_DANRE", "mass": { "chemical_mass": 317717.0, "monoisotopic_mass": 317717.0 }, "refseq": { "ac": "XP_699251", "name": "3'-5' exoribonuclease HELZ2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699251" }, "gene_names": [ { "name": "helz2b", "type": "recommended", "evidence": [ { "id": "A0A8N7URF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7" } ] }, { "name": "helz2b", "type": "synonym", "evidence": [ { "id": "XP_699251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699251" } ] } ], "protein_names": [ { "name": "3'-5' exoribonuclease HELZ2", "type": "synonym", "evidence": [ { "id": "XP_699251", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699251" }, { "id": "A0A8N7URF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_699251.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_699251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699251" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URF7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "helz2b", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7", "locus": {} } ], "crossref": [ { "id": "cd18808", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18808", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "570654", "url": "https://www.ncbi.nlm.nih.gov/gene/570654", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003593", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003593", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570654", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570654", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7URF7", "url": "https://www.orthodb.org/?gene=A0A8N7URF7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43788", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43788", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43788:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43788:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00773", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00773", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13086", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13086", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13087", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13087", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_699251", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699251", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7URF7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7URF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSTSHSRDAQLQQFMQMYELRAVCNGCTEKHSHISYTIIATPHRCSHDVLLARAKVRGSRWSRVFQRPTHPRPQRYEVCWYFQEDVGCRIHRDRCTFASSPEEAAVWNLQKHTNLDHRTIIHLITQRKRQAEGKKEAQPSFQELSSYQEKLLKEYRSSSNEILVISEHVDDVRVTHDENLSMDCLQEDNEIRWKFTITTERSLAHVALLKVENGAVFSLSDSLRNTIPPITHIAGHELRSSQSTYQLSVSFLSFHPGVYEQWLVFDFDMRPVLLRKLKVRVGQQFLVQPEEAEESECAEILSNERWNRGNRVIVPFFARKEEDEQLLSKYKPPQLNLQFNPHADHSLPLHRENYRERAHHFLFREEIAEEELISRLNVCGTVSLSNHLSDAMSLFYAAPGKLFANLKVSCSLTPDSPEGVVLKRGVQMALVNCKSTKASMSAKHRNHVYEAFVMKETVGEGHLSLELSTQCVSELELRKETTCEMEVQFQLNRLSFCQIHQAIDRLPDLHNVLPDFSNCCVPVNLTKQSQLNNKQQIALNFILGKCEDDKVAAPLLIYGPFGTGKTLCLASAAKELAHRSQNKVLICTYTNSSADLYVREHFHPYIINGHPTLKLLRIKANKGGSAIIATDDITRKYCLCSRDGQSFILPARSDLESHRIIITTTSIARHLHELKLPEGFFTHILIDEASQMLEGEALMALGLADKHTRVVLAGDHMQMAPKLFSVTDDKRSEHTLLNRLFHYYQDQSINIAKKSRIIFNENYRSTTEIVDFVSTYFYVSDGIKARGDVHPHPRLKPLIFHHVRGECHLSSTITSTSWLNYAEVNSVVNMVQVLLTDWPMEWGDKDPKQICVLSEGQQVAAIRIHLRRKGFYGVSVQNLANIQGKQFRVIIITTVHTRDKLLQLDSSCPEFFDDIRALNTALTRAQSLVVVIGDAGALCCFGKCSKVWRAYIEHCISKGSIKPDHFTRDVLQREVLEISKFQKTENVEKIETVVNLQAETDAILKEMENYDSDAQKSEDDNEQKRRIFTSAEKENLLEMVRNQPALYKRGELVMEGYQSGYIIPYDNPSERIDIKGRKNIGMSFPGDEVVVEIRRPDEGHLTGRVLGLTNRSPTSSECVCSLEDENYNRKKLNPDQNLVPKMMIPLDHTTTKIRILVKKEARKLIPLWKCVSGNWTITGGVPINEQTKQNYVFVVQILGWKEHCSFPLGRVTDILPVGTSLEEGLKILKSEFKLMSPPLMQENTLLEIRIDDKKRKDFTGLKTFTVDPPNAEVLDDAISINDLGSCYEIGVHVADVASFVSKDSSIDAFAKDMGATFYAPGKEPAFMFPKHLSTTCWSLLPGKDRKAISLIVKVEKQSGVITKKTFDLSMVKSKRQLTYNEAEDIICQCDGELRFDTLEDCVRVAYHFARSQRKTRLKEDWSYAQPNKHQKPGEREAHRMIEELNIMFNHEVSKFLSEYTDTKSCTPLRCQDSPNAEALEKISNQHMELIPFSSHLTFHLERQRMDLKNAITFTVYCSGSRDVHLNNNPNPEANSSPLSSQLRDAISVSESECYFEIGVHKADFFNYVSEDNIQNLGAQSDMWNLAPGKKRCAISLMLKVEKRNGKLVEEKMVLSRIRSCKALSYSEADSIINQLEEKEMKFGTLEDCILVVCRFALDHRTKRLSRQVNSSNPSDLASSEDSKCRLMMEELKLMFKRASDQIINQETQFPNASPGLVSRLKKYNEKFDSLQVLEECLGPNNGQNCGSFIILTSVWKKIESAALTCDFYKMADLISTDDIHPQLVPAIVQLSASINKAFFIRSLSCREALVGHYSLHLDSYTHASSPIRRYIDVVLQRLMHAVLGNRPVEYSQTDIDLLCEKCKRGEKRAQEYESKVEALQIAVNLQKQSTYKVAFVTVVKRDSESFKLSFPFDKGTFPEKLPVQYRNLQLEDQPLFIKKPKHVKLTWKKRIYGLSMTQSPLQNMKISSEIQQSTWQAIVEAVRDEKWDEAKSLVLAAHVKDNSRNSELSDTSRWDPDRTFTSEEDHYTDFQINLKVGDTVQVQLTSERDRGYWAPTVQLFRLSSSFEICVEHTDNPIKCFSRIADHPSKGSYSNVEEYVQIWRPLCEMESAATAVDDSDCVVIENVAITWDDSRLSGNFSLPEENIKKWAIEFDLGRCLLCIRKRDLEQNQAEQSELDPKYFTWVAHAVTTLCSDSPENSGNKFKIINFNVKYASMKIPKFKRNETFTVEIIPKLLPDIRKESAVNNLKGANELVQNIALKHRIVNQSSNQDVPLYLLMREEAPAGLPHLNESQFKALEKALNGKFTIIQGPPGTGKTVVGAYIVYWFSQLNSRNLWRLKDPTDKDKREVILYCGPSNKSVDVVAEYLLKFGEKLKLLRVYSRQMEMQEYPYPGSNLQLSHKSRQECSKPELRAITLHHRIRMGHNLYSQRITDFDDRIKSDPYSLTDTDIEEYKKLLNDARLHELERHDIILCTCTAAASPNLKKTLSARQILIDECAMATEPQTLVPLVSFKPEKVVLLGDHKQLRPIVKNNHVRRLGMTRSLFERYMDRAIMLDTQYRMHEEICKFPSEAYYNDMLKTVVRERTSVLNAETEGRRQSKRILFGDIRGEEIGLVVSTARGNENSKANFDEVKKAVEICIQLVTVGRVRPEDIAILSPYNAQVAQIRERLSDFELKGFTVTTITKSQGSEWQYVILSIVRSCPSDEIEPMPSREWLSKHIGFVGDENQINVGITRAQVGLCILGNQAVLNCSPAWQKLLKHYSGHGCVVTADQITVHRVR", "length": 2781, "header": "tr|A0A8N7URF7-1|A0A8N7URF7_DANRE Isoform 1 of 3'-5' exoribonuclease HELZ2 OS=Danio rerio OX=7955 GN=helz2b PE=3 SV=2 CANONICAL=A0A8N7URF7-1" }, "isoforms": [ { "isoform_ac": "A0A8N7URF7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7/entry#A0A8N7URF7-1", "sequence": { "sequence": "MSTSHSRDAQLQQFMQMYELRAVCNGCTEKHSHISYTIIATPHRCSHDVLLARAKVRGSRWSRVFQRPTHPRPQRYEVCWYFQEDVGCRIHRDRCTFASSPEEAAVWNLQKHTNLDHRTIIHLITQRKRQAEGKKEAQPSFQELSSYQEKLLKEYRSSSNEILVISEHVDDVRVTHDENLSMDCLQEDNEIRWKFTITTERSLAHVALLKVENGAVFSLSDSLRNTIPPITHIAGHELRSSQSTYQLSVSFLSFHPGVYEQWLVFDFDMRPVLLRKLKVRVGQQFLVQPEEAEESECAEILSNERWNRGNRVIVPFFARKEEDEQLLSKYKPPQLNLQFNPHADHSLPLHRENYRERAHHFLFREEIAEEELISRLNVCGTVSLSNHLSDAMSLFYAAPGKLFANLKVSCSLTPDSPEGVVLKRGVQMALVNCKSTKASMSAKHRNHVYEAFVMKETVGEGHLSLELSTQCVSELELRKETTCEMEVQFQLNRLSFCQIHQAIDRLPDLHNVLPDFSNCCVPVNLTKQSQLNNKQQIALNFILGKCEDDKVAAPLLIYGPFGTGKTLCLASAAKELAHRSQNKVLICTYTNSSADLYVREHFHPYIINGHPTLKLLRIKANKGGSAIIATDDITRKYCLCSRDGQSFILPARSDLESHRIIITTTSIARHLHELKLPEGFFTHILIDEASQMLEGEALMALGLADKHTRVVLAGDHMQMAPKLFSVTDDKRSEHTLLNRLFHYYQDQSINIAKKSRIIFNENYRSTTEIVDFVSTYFYVSDGIKARGDVHPHPRLKPLIFHHVRGECHLSSTITSTSWLNYAEVNSVVNMVQVLLTDWPMEWGDKDPKQICVLSEGQQVAAIRIHLRRKGFYGVSVQNLANIQGKQFRVIIITTVHTRDKLLQLDSSCPEFFDDIRALNTALTRAQSLVVVIGDAGALCCFGKCSKVWRAYIEHCISKGSIKPDHFTRDVLQREVLEISKFQKTENVEKIETVVNLQAETDAILKEMENYDSDAQKSEDDNEQKRRIFTSAEKENLLEMVRNQPALYKRGELVMEGYQSGYIIPYDNPSERIDIKGRKNIGMSFPGDEVVVEIRRPDEGHLTGRVLGLTNRSPTSSECVCSLEDENYNRKKLNPDQNLVPKMMIPLDHTTTKIRILVKKEARKLIPLWKCVSGNWTITGGVPINEQTKQNYVFVVQILGWKEHCSFPLGRVTDILPVGTSLEEGLKILKSEFKLMSPPLMQENTLLEIRIDDKKRKDFTGLKTFTVDPPNAEVLDDAISINDLGSCYEIGVHVADVASFVSKDSSIDAFAKDMGATFYAPGKEPAFMFPKHLSTTCWSLLPGKDRKAISLIVKVEKQSGVITKKTFDLSMVKSKRQLTYNEAEDIICQCDGELRFDTLEDCVRVAYHFARSQRKTRLKEDWSYAQPNKHQKPGEREAHRMIEELNIMFNHEVSKFLSEYTDTKSCTPLRCQDSPNAEALEKISNQHMELIPFSSHLTFHLERQRMDLKNAITFTVYCSGSRDVHLNNNPNPEANSSPLSSQLRDAISVSESECYFEIGVHKADFFNYVSEDNIQNLGAQSDMWNLAPGKKRCAISLMLKVEKRNGKLVEEKMVLSRIRSCKALSYSEADSIINQLEEKEMKFGTLEDCILVVCRFALDHRTKRLSRQVNSSNPSDLASSEDSKCRLMMEELKLMFKRASDQIINQETQFPNASPGLVSRLKKYNEKFDSLQVLEECLGPNNGQNCGSFIILTSVWKKIESAALTCDFYKMADLISTDDIHPQLVPAIVQLSASINKAFFIRSLSCREALVGHYSLHLDSYTHASSPIRRYIDVVLQRLMHAVLGNRPVEYSQTDIDLLCEKCKRGEKRAQEYESKVEALQIAVNLQKQSTYKVAFVTVVKRDSESFKLSFPFDKGTFPEKLPVQYRNLQLEDQPLFIKKPKHVKLTWKKRIYGLSMTQSPLQNMKISSEIQQSTWQAIVEAVRDEKWDEAKSLVLAAHVKDNSRNSELSDTSRWDPDRTFTSEEDHYTDFQINLKVGDTVQVQLTSERDRGYWAPTVQLFRLSSSFEICVEHTDNPIKCFSRIADHPSKGSYSNVEEYVQIWRPLCEMESAATAVDDSDCVVIENVAITWDDSRLSGNFSLPEENIKKWAIEFDLGRCLLCIRKRDLEQNQAEQSELDPKYFTWVAHAVTTLCSDSPENSGNKFKIINFNVKYASMKIPKFKRNETFTVEIIPKLLPDIRKESAVNNLKGANELVQNIALKHRIVNQSSNQDVPLYLLMREEAPAGLPHLNESQFKALEKALNGKFTIIQGPPGTGKTVVGAYIVYWFSQLNSRNLWRLKDPTDKDKREVILYCGPSNKSVDVVAEYLLKFGEKLKLLRVYSRQMEMQEYPYPGSNLQLSHKSRQECSKPELRAITLHHRIRMGHNLYSQRITDFDDRIKSDPYSLTDTDIEEYKKLLNDARLHELERHDIILCTCTAAASPNLKKTLSARQILIDECAMATEPQTLVPLVSFKPEKVVLLGDHKQLRPIVKNNHVRRLGMTRSLFERYMDRAIMLDTQYRMHEEICKFPSEAYYNDMLKTVVRERTSVLNAETEGRRQSKRILFGDIRGEEIGLVVSTARGNENSKANFDEVKKAVEICIQLVTVGRVRPEDIAILSPYNAQVAQIRERLSDFELKGFTVTTITKSQGSEWQYVILSIVRSCPSDEIEPMPSREWLSKHIGFVGDENQINVGITRAQVGLCILGNQAVLNCSPAWQKLLKHYSGHGCVVTADQITVHRVR", "length": 2781, "header": "tr|A0A8N7URF7-1|A0A8N7URF7_DANRE Isoform 1 of 3'-5' exoribonuclease HELZ2 OS=Danio rerio OX=7955 GN=helz2b PE=3 SV=2 CANONICAL=A0A8N7URF7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "A0A8N7URF7", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8N7URF7" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "A0A8N7URF7", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=A0A8N7URF7" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:570654", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570654", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 5, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URF7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URF7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7" } ], "pmid": "" }, { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URF7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7" } ], "pmid": "" }, { "name": "RNA nuclease activity", "id": "GO:0004540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004540", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URF7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7" } ], "pmid": "" }, { "name": "5'-3' DNA helicase activity", "id": "GO:0043139", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043139", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URF7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URF7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1110, "end_pos": 1112, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1174, "end_pos": 1176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1534, "end_pos": 1536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1669, "end_pos": 1671, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1711, "end_pos": 1713, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2138, "end_pos": 2140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2224, "end_pos": 2226, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2266, "end_pos": 2268, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2291, "end_pos": 2293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2358, "end_pos": 2360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2751, "end_pos": 2753, "annotation": "n_glycosylation_sequon" }, { "start_pos": 524, "end_pos": 526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 591, "end_pos": 593, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7URF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7" }, { "id": "SM00382", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00382" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AAA+ ATPase", "eco_id": "ECO_0000259", "start_pos": 551, "end_pos": 733, "start_aa": "Val", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7URF7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF7" }, { "id": "SM00955", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00955" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RNB", "eco_id": "ECO_0000259", "start_pos": 1255, "end_pos": 1845, "start_aa": "Arg", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1110, "end_pos": 1112 }, { "start_pos": 1174, "end_pos": 1176 }, { "start_pos": 1534, "end_pos": 1536 }, { "start_pos": 1669, "end_pos": 1671 }, { "start_pos": 1711, "end_pos": 1713 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 2138, "end_pos": 2140 }, { "start_pos": 2224, "end_pos": 2226 }, { "start_pos": 2266, "end_pos": 2268 }, { "start_pos": 2291, "end_pos": 2293 }, { "start_pos": 2358, "end_pos": 2360 }, { "start_pos": 2751, "end_pos": 2753 }, { "start_pos": 524, "end_pos": 526 }, { "start_pos": 591, "end_pos": 593 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": "fuzzy_sites", "count": 1 }, { "field": "fuzzy_o_linked_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycan_sites", "count": 1 }, { "field": "fuzzy_o_linked_glycans", "count": 1 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 1 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 1 }, { "field": "exact_sites", "count": 0 }, { "field": 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"A0A8N7URF9-1", "uniprot_ac": "A0A8N7URF9", "uniprot_id": "A0A8N7URF9_DANRE", "mass": { "chemical_mass": 63382.0, "monoisotopic_mass": 63382.0 }, "refseq": { "ac": "XP_699490", "name": "kelch-like protein 35", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699490" }, "gene_names": [ { "name": "klhl35", "type": "recommended", "evidence": [ { "id": "A0A8N7URF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF9" } ] }, { "name": "klhl35", "type": "synonym", "evidence": [ { "id": "XP_699490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699490" } ] } ], "protein_names": [ { "name": "Kelch-like protein 35", "type": "synonym", "evidence": [ { "id": "A0A8N7URF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF9/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 35", "type": "synonym", "evidence": [ { "id": "XP_699490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699490" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_699490.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_699490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699490" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URF9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "klhl35", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091118-66", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-66", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7URF9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7URF9", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd18265", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18265", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18474", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18474", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "570873", "url": "https://www.ncbi.nlm.nih.gov/gene/570873", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030601", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030601", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570873", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570873", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7URF9", "url": "https://www.orthodb.org/?gene=A0A8N7URF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_699490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_699490", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7URF9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7URF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091118-66", "url": "https://zfin.org/ZDB-GENE-091118-66", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGFGSSGELMDRSNVSFCSGSCHAEHILQVLNSYRRSGTFTDVVLLVDGCEFPCHRATLCASSGFFRTMFGSHFTESRQAAVTLQDVSRAAMEKLLDFMYEGRLTLDEENVQSVFQAADRLDVPVLYKACVQFLQERVSHCNCLGLMSFAHAYGLQPLQEQCETLLYRDLQQILRHPEFLQLEKQQVLDVLCCERLQVREEVLVEAALRWVHQQPAKRSAHLRELLEPLRLPLLDQAFFCGTLEADEMVRDQPELRDLLQEARLYHAYGREVQSKRTTPRPRSGWAEMIFVFGGCDKSGFSRLSFMEKLNVCSGQWQGAAAVPGYCKSEFAACELQNDIYLSGGQLNSADVWRFMSSLGQWVRVCALSRGRWRHKMVSLCGKLYVVGGYNGRERVSTVERYSPHENSWISVSELPLPVSSAALASCCGKLYVIGGAISDHANTNQVQCYDPLTDSWSSVSPCPFSHRSISAVSLNGSIYVAGGLMEHIYCYTPSKDCWSPAAKLPVRVEGCGLTVCAGKVYVVGGRTDEATAVNQSWSFDPLSGKVTEETPMTRCVSYHGCVSVLQRL", "length": 568, "header": "tr|A0A8N7URF9-1|A0A8N7URF9_DANRE Isoform 1 of Kelch-like protein 35 OS=Danio rerio OX=7955 GN=klhl35 PE=4 SV=1 CANONICAL=A0A8N7URF9-1" }, "isoforms": [ { "isoform_ac": "A0A8N7URF9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF9/entry#A0A8N7URF9-1", "sequence": { "sequence": "MGFGSSGELMDRSNVSFCSGSCHAEHILQVLNSYRRSGTFTDVVLLVDGCEFPCHRATLCASSGFFRTMFGSHFTESRQAAVTLQDVSRAAMEKLLDFMYEGRLTLDEENVQSVFQAADRLDVPVLYKACVQFLQERVSHCNCLGLMSFAHAYGLQPLQEQCETLLYRDLQQILRHPEFLQLEKQQVLDVLCCERLQVREEVLVEAALRWVHQQPAKRSAHLRELLEPLRLPLLDQAFFCGTLEADEMVRDQPELRDLLQEARLYHAYGREVQSKRTTPRPRSGWAEMIFVFGGCDKSGFSRLSFMEKLNVCSGQWQGAAAVPGYCKSEFAACELQNDIYLSGGQLNSADVWRFMSSLGQWVRVCALSRGRWRHKMVSLCGKLYVVGGYNGRERVSTVERYSPHENSWISVSELPLPVSSAALASCCGKLYVIGGAISDHANTNQVQCYDPLTDSWSSVSPCPFSHRSISAVSLNGSIYVAGGLMEHIYCYTPSKDCWSPAAKLPVRVEGCGLTVCAGKVYVVGGRTDEATAVNQSWSFDPLSGKVTEETPMTRCVSYHGCVSVLQRL", "length": 568, "header": "tr|A0A8N7URF9-1|A0A8N7URF9_DANRE Isoform 1 of Kelch-like protein 35 OS=Danio rerio OX=7955 GN=klhl35 PE=4 SV=1 CANONICAL=A0A8N7URF9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:570873", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570873", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LIA3-1", "protein_name": "Kelch-like family member 35", "gene_name": "Klhl35", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSVFSPGRMRESPGREESEAGMEAPCAASCHAQRILQTLNAYRRSGTLTDVVLRAGGRDFPCHRAALSAASAHFRGLFAAGLPERTAAVVPVGPETPGTAAALAVVLDYVYGAGVRLRAEDEAAAVLALAERLGVAGLREACARFLEGRLRAANSLSLRRVAAAFSLASLAERCGRVLRQAFVEVTRHADFLELAPDEVAALLADPALRVAREEAVFEAAMRWVRHDAPARRGQLRRLLEHVRLPLLAPAYFLEKVEADELLQACGDCRPLLLEARACFILGPEAGALRARPRRFMDLAEVIVVIGGCDRKGLLKLPFADAYHPESQRWTPLPSLPGYMRSEFASCALRNDIYVSGGHINSRDVWMFNSHLNTWIKVASMHKGRWRHKMVALQGQLFAVGGFDGLRRLRSVERYDPFSNTWAATAPLPEAVSSAAVAPCAGQLYVIGGAGQDGVNTDKVQCFDPKEDQWSLRSPAPFLQRCLEAVSLGDTIYVVGGLMSKIFTYDPGSDVWREAADLPSPVESCGVTVCDGKVHILGGRDEHGESTNSVFTFDPGSGQVEAQPSLQRCTSSHGCVTIVQSLSR", "length": 584 }, "evidence": [ { "id": "RGD:1565895", "url": "https://alliancegenome.org/gene/RGD:1565895#orthology", "database": "AGR" }, { "id": "MGI:1919434", "url": "https://alliancegenome.org/gene/MGI:1919434#orthology", "database": "AGR" }, { "id": "HGNC:26597", "url": "https://alliancegenome.org/gene/HGNC:26597#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091118-66", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-66#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PF15-1", "protein_name": "Kelch-like protein 35", "gene_name": "KLHL35", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRQGHAPEESEPGCEAPCAGPCHAQRVLQALNAYRRSGTLTDVVLRAGGRDFPCHRAALSAGSAYFRSLFAAGRPERGPAVVPVVPVAPEAPGTSPAGAAAALAVVLDYVYGAGVRLRAEDEAAAVLALAERLGVAGLREACVRFLEGRLRAANSLALRRVAAAFSLAPLAERCGRVLRQAFAEVARHADFLELAPDEVVALLADPALGVAREEAVFEAAMRWVRHDAPARRGQLRRLLEHVRLPLLAPAYFLEKVEADELLQACGECRPLLLEARACFILGREAGALRTRPRRFMDLAEVIVVIGGCDRKGLLKLPFADAYHPESQRWTPLPSLPGYTRSEFAACALRNDVYVSGGHINSHDVWMFSSHLHTWIKVASLHKGRWRHKMAVVQGQLFAVGGFDGLRRLHSVERYDPFSNTWAAAAPLPEAVSSAAVASCAGKLFVIGGARQGGVNTDKVQCFDPKEDRWSLRSPAPFSQRCLEAVSLEDTIYVMGGLMSKIFTYDPGTDVWGEAAVLPSPVESCGVTVCDGKVHILGGRDDRGESTDKVFTFDPSSGQVEVQPSLQRCTSSHGCVTIIQSLGR", "length": 583 }, "evidence": [ { "id": "RGD:1565895", "url": "https://alliancegenome.org/gene/RGD:1565895#orthology", "database": "AGR" }, { "id": "MGI:1919434", "url": "https://alliancegenome.org/gene/MGI:1919434#orthology", "database": "AGR" }, { "id": "HGNC:26597", "url": "https://alliancegenome.org/gene/HGNC:26597#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091118-66", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-66#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZ49-1", "protein_name": "Kelch-like protein 35", "gene_name": "Klhl35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRETPEREEEPGTEAPCAASCHAQRILQTLNAYRRSGTLTDVVLRAGGRDFPCHRAALSAASAHFRGLFAAGRPERAAAVVPVGPETPGTAAALAVVLDYVYGAGVRLRAEDEAAAVLALAERLGVAGLREACARFLEGRLRAANSLALRRVAAAFSLASLAERCGRVLRQAFVEVTRHADFLELAPDEVAALLADPALRVAREEAVFEAAMRWVRHDAPARRGQLRRLLEHVRLPLLAPAYFLEKVEADELLQACGDCRPLLLEARACFILGREAGALRARPRRFMDLAEVIVVIGGCDRKGLLKLPFADAYHPESQRWTPLPSLPGYTRSEFASCALRNDIYVSGGHINSRDVWMFSSHLNTWIKVASMHKGRWRHKMVALQGQLFAVGGFDGLRRLRSVERYDPFSNTWAAIAPLPEAVSSAAVAPCAGQLYVIGGAGQDGVNTDKVQCFDPKEDQWSLRSPAPFLQRCLEAVSLEDTIYVVGGLMSKIFTYDPGSDVWREAADLPSPVESCGVTVCDGKVHILGGRDEHGESTSSVFTFDPGTGQVEAQPSLQRCTSSHGCVTIVQSLSR", "length": 574 }, "evidence": [ { "id": "RGD:1565895", "url": "https://alliancegenome.org/gene/RGD:1565895#orthology", "database": "AGR" }, { "id": "MGI:1919434", "url": "https://alliancegenome.org/gene/MGI:1919434#orthology", "database": "AGR" }, { "id": "HGNC:26597", "url": "https://alliancegenome.org/gene/HGNC:26597#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091118-66", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-66#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URF9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF9" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URF9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URF9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7URF9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7URF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 475, "end_pos": 477, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7URF9", "database": "UniProtKB", "url": 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This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_706608.1. 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Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_689131.4. 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[ "Protein Classification" ] }, { "id": "PTHR10794:SF78", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10794:SF78", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_689131", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689131", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UT08", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UT08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131121-270", "url": "https://zfin.org/ZDB-GENE-131121-270", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLEWIGTFCFLILMAILWPVAKCFGAASHYTLLLPRRDSKRPAERCDSKLEEKGESAAVALICKPSALANYLLKHCMTFCKSLSIPSWNWRVSSSLQTVFGALWPVECPVHFIRDHLQLSDDGLVALDWAVVGAAHHKRRRTSSNSTSPVLLIIPNSFGRITRNVLKLCEAALSHGYLPVIFNRRSQNGTPLSTIRLQQFGDPTDLREAVRYIRYRQPAGQIYAVSESTGSGLLLSYLGECGSSSYVTAAACLSPIFRCQSWFESGPSWPFHWALLLYQKICLSRYKTVLGELVHIDSVFSSCSLKEMEEALFCHFSSKGVPVEGTGSWEAYWERNDPLRDIDEVAIPVLCVCSQDDPIRGDPRTTLPFELFENNPHFFLLLTACGGHCGFSTSDEGPVVWSHQALLEFFRATTDFFAAEERAKLAARRRGLSGAGKTFRHRSVSTCKRLPVCSHNIHAIYNWQRSYTR", "length": 469, "header": "tr|A0A8N7UT08-1|A0A8N7UT08_DANRE Isoform 1 of Protein ABHD15 OS=Danio rerio OX=7955 GN=abhd15a PE=3 SV=1 CANONICAL=A0A8N7UT08-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UT08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT08/entry#A0A8N7UT08-1", "sequence": { "sequence": "MLEWIGTFCFLILMAILWPVAKCFGAASHYTLLLPRRDSKRPAERCDSKLEEKGESAAVALICKPSALANYLLKHCMTFCKSLSIPSWNWRVSSSLQTVFGALWPVECPVHFIRDHLQLSDDGLVALDWAVVGAAHHKRRRTSSNSTSPVLLIIPNSFGRITRNVLKLCEAALSHGYLPVIFNRRSQNGTPLSTIRLQQFGDPTDLREAVRYIRYRQPAGQIYAVSESTGSGLLLSYLGECGSSSYVTAAACLSPIFRCQSWFESGPSWPFHWALLLYQKICLSRYKTVLGELVHIDSVFSSCSLKEMEEALFCHFSSKGVPVEGTGSWEAYWERNDPLRDIDEVAIPVLCVCSQDDPIRGDPRTTLPFELFENNPHFFLLLTACGGHCGFSTSDEGPVVWSHQALLEFFRATTDFFAAEERAKLAARRRGLSGAGKTFRHRSVSTCKRLPVCSHNIHAIYNWQRSYTR", "length": 469, "header": "tr|A0A8N7UT08-1|A0A8N7UT08_DANRE Isoform 1 of Protein ABHD15 OS=Danio rerio OX=7955 GN=abhd15a PE=3 SV=1 CANONICAL=A0A8N7UT08-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:560644", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560644", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z8B6-1", "protein_name": "Protein ABHD15", "gene_name": "Abhd15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPPWPAALALLLAALALLLLRPWKRAVGARTSVRDHEEQEVVSGGPADHFSDRREPLPGGCSLICKPSALAQCLLRALRRSAALEPSPRSWLSGPHLQTFCHFILPVGPDPELAREYLQLADDGLVALDWVIGPCARGRRVTNPGSLPPVLLVIPNAWGRLTRNVLGLCLLALEHGYYPVIFHRRGHHGCPLVSPRLQPFGDPSDLKEAVTYIRFRHPAAPLFAVSEGSGSALLLSYLGECGSSSYVTGAACISPVLRCREWFEAGLPWPYERGFLLYQKIALSRYASALEDTVDTGKLFKSSSLREFEETLFCHTKSLPISWDTYWDLNDPLRDVDEAAVPVLCICSADDPVCGPPDRTLPAELFHTNPYFFLLLSSHGGHCGFLRPEPLPAWSHEIILESFRALTEFFRMEERMKGLSRRRTSFLGGRRRWGGLQKREVSPSSNLEEIFDWKRSYTR", "length": 459 }, "evidence": [ { "id": "MGI:1914727", "url": "https://alliancegenome.org/gene/MGI:1914727#orthology", "database": "AGR" }, { "id": "HGNC:26971", "url": "https://alliancegenome.org/gene/HGNC:26971#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q02891-1", "protein_name": "Medium-chain fatty acid ethyl ester synthase/esterase 1", "gene_name": "EEB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFRSGYYPTVTPSHWGYNGTVKHVLGEKGTKSLAFRDSKRQIPLHEFVTKHVPTLKDGANFRLNSLLFTGYLQTLYLSAGDFSKKFQVFYGREIIKFSDGGVCTADWVMPEWEQTYSLNAEKASFNEKQFSNDEKATHPKGWPRLHPRTRYLSSEELEKCHSKGYSYPLVVVLHGLAGGSHEPLIRALSEDLSKVGDGKFQVVVLNARGCSRSKVTTRRIFTALHTGDVREFLNHQKALFPQRKIYAVGTSFGAAMLTNYLGEEGDNCPLNAAVALSNPWDFVHTWDKLAHDWWSNHIFSRTLTQFLTRTVKVNMNELQVPENFEVSHKPTVEKPVFYTYTRENLEKAEKFTDILEFDNLFTAPSMGLPDGLTYYRKASSINRLPNIKIPTLIINATDDPVTGENVIPYKQARENPCVLLCETDLGGHLAYLDNESNSWLTKQAAEFLGSFDELVL", "length": 456 }, "evidence": [ { "id": "MGI:1914727", "url": "https://alliancegenome.org/gene/MGI:1914727#orthology", "database": "AGR" }, { "id": "HGNC:26971", "url": "https://alliancegenome.org/gene/HGNC:26971#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q03649-1", "protein_name": "Monoacylglycerol lipase", "gene_name": "MGL2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRLKELLPNFLIVHQEVPEDPIAFKSTDKRENENKEITIPELIDTKVPELADGATDTLYGLLVNGHLQTAYGSFRHFDNIYKVQYKRMIIKYPHGGEGTVDFAVNGRSTKRRKVEKEYVPTSQPVFNGNLKRRYSYYSPDDPKLNSDDAKPMLIILHGLTGGSRESYVRAIVHEITTKYDFEACVFNARGCCYSAITTPLLYNGGWTNDIRYCVNDLRKRFPNRKFYMMGFSLGASIMTNYLGEESDRTKIECAISVSNPFDLYNSAYFINSTPMGSRFYSPALGHNLLRMVRNHLSTLEENPDFKDVIEKHLKKIRTVRQFDNLLTGPMFGYKNAEEYYKNASSYKRIPGIRTPFIALHAQDDPIVGGDLPIDQIKSNPYTLLLETSTGGHVGWFKDRSGRRWYAEPLCRFLKIFHDEITVKGLKPDLENVQLPDPNCEPIATTFRAN", "length": 449 }, "evidence": [ { "id": "MGI:1914727", "url": "https://alliancegenome.org/gene/MGI:1914727#orthology", "database": "AGR" }, { "id": "HGNC:26971", "url": "https://alliancegenome.org/gene/HGNC:26971#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5F2F2-1", "protein_name": "Protein ABHD15", "gene_name": "Abhd15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPPWAAALALLLAALALLLLRPWKRAVGARTSVRDHEEQEVASGGPADQFSDRREALPGGCSLICKPSALAQCLLRALRRSAALEPSPRSWLSGPHLQTFCHFILPVGPGPELAREYLQLADDGLVALDWVIGPCARGRRVTNPGSLPPVLLVIPNAWGRLTRNVLGLCLLALERGYYPVIFHRRGHHGCPLVSPRLQPFGDPSDLKEAVTYIRFRHPAAPLFAVSEGSGSALLLSYLGECGSSSYVTGAACISPVLRCREWFEAGLPWPYERGFLLHQKISLSRYASALEDTVDTGKLFRSGSLREFEETLFCHTKSCPISWDTYWDLNDPLRDVDEAAVPVLCICSADDPVCGPPEHTLPAELFHSNPYFFLLLSHHGGHCGFLRPEPLPAWSHEVILESFRALTEFFRMEERMKGLSRRRTSFLGGRRRWGGLQKREVSPSSNLEEIFNWKRSYTR", "length": 459 }, "evidence": [ { "id": "MGI:1914727", "url": "https://alliancegenome.org/gene/MGI:1914727#orthology", "database": "AGR" }, { "id": "HGNC:26971", "url": "https://alliancegenome.org/gene/HGNC:26971#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-270", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-270#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UXT9-1", "protein_name": "Protein ABHD15", "gene_name": "ABHD15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPPWGAALALILAVLALLGLLGPRLRGPWGRAVGERTLPGAQDRDDGEEADGGGPADQFSDGREPLPGGCSLVCKPSALAQCLLRALRRSEALEAGPRSWFSGPHLQTLCHFVLPVAPGPELAREYLQLADDGLVALDWVVGPCVRGRRITSAGGLPAVLLVIPNAWGRLTRNVLGLCLLALERGYYPVIFHRRGHHGCPLVSPRLQPFGDPSDLKEAVTYIRFRHPAAPLFAVSEGSGSALLLSYLGECGSSSYVTGAACISPVLRCREWFEAGLPWPYERGFLLHQKIALSRYATALEDTVDTSRLFRSRSLREFEEALFCHTKSFPISWDTYWDRNDPLRDVDEAAVPVLCICSADDPVCGPPDHTLTTELFHSNPYFFLLLSRHGGHCGFLRQEPLPAWSHEVILESFRALTEFFRTEERIKGLSRHRASFLGGRRRGGALQRREVSSSSNLEEIFNWKRSYTR", "length": 468 }, "evidence": [ { "id": "MGI:1914727", "url": "https://alliancegenome.org/gene/MGI:1914727#orthology", "database": "AGR" }, { "id": "HGNC:26971", "url": "https://alliancegenome.org/gene/HGNC:26971#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-270", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-270#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UT08", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT08" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 188, "end_pos": 190, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 145, "end_pos": 147 }, { "start_pos": 188, "end_pos": 190 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UT82-1", "uniprot_ac": "A0A8N7UT82", "uniprot_id": "A0A8N7UT82_DANRE", "mass": { "chemical_mass": 141486.0, "monoisotopic_mass": 141486.0 }, "refseq": { "ac": "XP_693684", "name": "codanin-1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693684" }, "gene_names": [ { "name": "cdan1", "type": "recommended", "evidence": [ { "id": "A0A8N7UT82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT82" } ] }, { "name": "cdan1", "type": "synonym", "evidence": [ { "id": "XP_693684", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693684" } ] } ], "protein_names": [ { "name": "Codanin-1", "type": "synonym", "evidence": [ { "id": "A0A8N7UT82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT82/entry#names_and_taxonomy" } ] }, { "name": "codanin-1", "type": "synonym", "evidence": [ { "id": "XP_693684", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693684" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_693684.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_693684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693684" } ] } ], "disease": [ { "disease_id": "DOID:0111396", "recommended_name": { "id": "DOID:0111396", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111396", "name": "congenital dyserythropoietic anemia type I", "description": "A congenital dyserythropoietic anemia characterized by autosomal recessive inheritance of macrocytic anemia, ineffective erythropoiesis, and secondary hemochromatosis." }, "synonyms": [ { "id": "DOID:0111396", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111396", "name": "CDA I", "description": "" }, { "id": "DOID:0111396", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111396", "name": "CDA type 1", "description": "" }, { "id": "DOID:0111396", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111396", "name": "CDA type I", "description": "" }, { "id": "DOID:0111396", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111396", "name": "Congenital dyserythropoietic anaemia type 1", "description": "" }, { "id": "DOID:0111396", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111396", "name": "Congenital dyserythropoietic anemia type 1", "description": "" }, { "id": "DOID:0111396", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111396", "name": "congenital dyserythropoietic anaemia type I", "description": "" }, { "id": "DOID:0111396", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111396", "name": "CDA1", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111396", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111396" } ] }, { "disease_id": "DOID:0111398", "recommended_name": { "id": "DOID:0111398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111398", "name": "congenital dyserythropoietic anemia type Ia", "description": "A congenital dyserythropoietic anemia type I that has_material_basis_in homozygous or compound heterozygous mutation in the CDAN1 gene on chromosome 15q15.2." }, "synonyms": [ { "id": "DOID:0111398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111398", "name": "CDA Ia", "description": "" }, { "id": "DOID:0111398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111398", "name": "CDAN1A", "description": "" }, { "id": "MONDO:0009135", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009135", "name": "anemia, congenital dyserythropoietic, type 1a", "description": "" }, { "id": "MONDO:0009135", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009135", "name": "anemia, congenital dyserythropoietic, type 1a", "description": "" }, { "id": "MONDO:0009135", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009135", "name": "anemia, congenital dyserythropoietic, type Ia", "description": "" }, { "id": "MONDO:0009135", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009135", "name": "CDAN1A", "description": "" }, { "id": "MIM:224120", "resource": "MIM", "url": "https://www.omim.org/entry/224120", "name": "Anemia, congenital dyserythropoietic, 1A", "description": "Anemia, congenital dyserythropoietic, 1A" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111398" } ] }, { "disease_id": "DOID:1338", "recommended_name": { "id": "DOID:1338", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1338", "name": "congenital dyserythropoietic anemia", "description": "A congenital hemolytic anemia characterized by ineffective erythropoiesis, and resulting from a decrease in the number of red blood cells (RBCs) in the body and a less than normal quantity of hemoglobin in the blood." }, "synonyms": [ { "id": "DOID:1338", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1338", "name": "congenital dyshaematopoietic anaemia", "description": "" }, { "id": "MONDO:0009135", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009135", "name": "anemia, congenital dyserythropoietic, type 1a", "description": "" }, { "id": "MONDO:0009135", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009135", "name": "anemia, congenital dyserythropoietic, type 1a", "description": "" }, { "id": "MONDO:0009135", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009135", "name": "anemia, congenital dyserythropoietic, type Ia", "description": "" }, { "id": "MONDO:0009135", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009135", "name": "CDAN1A", "description": "" }, { "id": "MIM:224120", "resource": "MIM", "url": "https://www.omim.org/entry/224120", "name": "Anemia, congenital dyserythropoietic, 1A", "description": "Anemia, congenital dyserythropoietic, 1A" } ], "unlinked_id_list": [], "evidence": [ { "id": "1338", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1338" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UT82", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT82" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cdan1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT82", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110411-280", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-280", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UT82", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UT82", "database": "AlphaFoldDB", "categories": [] }, { "id": "565314", "url": "https://www.ncbi.nlm.nih.gov/gene/565314", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040031", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040031", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565314", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565314", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UT82", "url": "https://www.orthodb.org/?gene=A0A8N7UT82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28678:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28678:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15296", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15296", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_693684", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693684", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UT82", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UT82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110411-280", "url": "https://zfin.org/ZDB-GENE-110411-280", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAALLESVLQSKVELSEAVLWLKGLHVCESQNFPSRVTKEEFVPFLLNFLRDQSSQTLTHGPATPAKTPSTSRSVRIQNSSERRVSKSTPVQGLRSASRVQLFSPAPFTSPGGGKNDQDTPFTGSLCLSGISALSSPSFSSVWSPVPRNSPSERRSAQRPSLGDFMTSPPETQPSPSAPPHRGRRRSAGFGGGTSSRQTGARGAVSEEGGGRRSRGGGRNDSVSPQTQVQLNFNNLEDFPPMAQPSPIATKPSRRINPTPVSAERPNSKPKSCFTSTPLSLPASPPKIPESTGSPHNLQEERELLKRERSKLAQQTSSPLKTNSEICTPTKTVHMQGSKVTPDSQLPCPDPDKVTQKSELDLLAGLYCACISENLVPCIFLEMFFVLQLLTSRGVSGSESAEQGISVCEDSPDVLEKAYLGNVHNCVYFSVRVLEKQFELVSHLDKCTLRLLSENERVGTFSSSLKDCLAEAQDNCTAKVPPSPPLFVHSVPFQPATDNRSNFSSDKAFHTFKKQRDVFYGLLREWEDSHKEPGWDFEAALGNRVRMMVSQLTAAGSQSHFARLFQKQLVQMCKGPSVLASSSDAPDADLLGMLGADSLGRLKRLQQRLVQPQSLIGPCPPPSFPGHQEFFKGFLQTASSCQLNQHLKDGLCQQLLKLDEVSILGPDASPAQGEKTADGDMEQQDEKQRFSSVLLTARLLAKFLGFITFLPYQTSELPSRDIQDAAVALRSKSFPVLDVCTVLRNSVHRRRTILTVPWMVEFLSMLDYIGPLLPCYRTALCLLLQIYKRMVLGRGGELCYMNQLLMVAVLGWLFQIPVFPEDLFFSADLKEEMKELENKTSSQGLDTLPLVDQQLLYTCCPYLGEFRKLLAAFVAGSTSKSGGLIRKITPTSAEPRGPSTTRSQQKLQVDLEQAFFHNQPPSLRRTVEFVAERVGSNCVKHIKATLVLELVRGGEKTLRDSLGMEGVNTAKLNDCICAQLCDAGMQALERATRFCSENAPGAVRVLLPLETSPSVLTTAKSITTRLATEKACSWLSSNITTLLKREWKSAFERVMKSVPSPLSVDAEEAEGLSRSQQVQKSASGLSAGSTCVPGCAHKVPLGSEVMIEIKDVLSVAVGPRSDDEVFTVRQIESVLDRVGQTLGCRKRLSPVVEQMLLRCTVQLACKLVSGELPLVSSAEGNKRPDLLERFLVLWSWTPAPPLHLLLTEPTLTAIFTATDRERTDYLFLIRQLIERGLLGEQEVGTNWAKLSALSWPEESVEKFQQLSLATQFSMPQLPNHRDLLQVSQ", "length": 1288, "header": "tr|A0A8N7UT82-1|A0A8N7UT82_DANRE Isoform 1 of Codanin-1 OS=Danio rerio OX=7955 GN=cdan1 PE=1 SV=1 CANONICAL=A0A8N7UT82-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UT82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT82/entry#A0A8N7UT82-1", "sequence": { "sequence": "MAALLESVLQSKVELSEAVLWLKGLHVCESQNFPSRVTKEEFVPFLLNFLRDQSSQTLTHGPATPAKTPSTSRSVRIQNSSERRVSKSTPVQGLRSASRVQLFSPAPFTSPGGGKNDQDTPFTGSLCLSGISALSSPSFSSVWSPVPRNSPSERRSAQRPSLGDFMTSPPETQPSPSAPPHRGRRRSAGFGGGTSSRQTGARGAVSEEGGGRRSRGGGRNDSVSPQTQVQLNFNNLEDFPPMAQPSPIATKPSRRINPTPVSAERPNSKPKSCFTSTPLSLPASPPKIPESTGSPHNLQEERELLKRERSKLAQQTSSPLKTNSEICTPTKTVHMQGSKVTPDSQLPCPDPDKVTQKSELDLLAGLYCACISENLVPCIFLEMFFVLQLLTSRGVSGSESAEQGISVCEDSPDVLEKAYLGNVHNCVYFSVRVLEKQFELVSHLDKCTLRLLSENERVGTFSSSLKDCLAEAQDNCTAKVPPSPPLFVHSVPFQPATDNRSNFSSDKAFHTFKKQRDVFYGLLREWEDSHKEPGWDFEAALGNRVRMMVSQLTAAGSQSHFARLFQKQLVQMCKGPSVLASSSDAPDADLLGMLGADSLGRLKRLQQRLVQPQSLIGPCPPPSFPGHQEFFKGFLQTASSCQLNQHLKDGLCQQLLKLDEVSILGPDASPAQGEKTADGDMEQQDEKQRFSSVLLTARLLAKFLGFITFLPYQTSELPSRDIQDAAVALRSKSFPVLDVCTVLRNSVHRRRTILTVPWMVEFLSMLDYIGPLLPCYRTALCLLLQIYKRMVLGRGGELCYMNQLLMVAVLGWLFQIPVFPEDLFFSADLKEEMKELENKTSSQGLDTLPLVDQQLLYTCCPYLGEFRKLLAAFVAGSTSKSGGLIRKITPTSAEPRGPSTTRSQQKLQVDLEQAFFHNQPPSLRRTVEFVAERVGSNCVKHIKATLVLELVRGGEKTLRDSLGMEGVNTAKLNDCICAQLCDAGMQALERATRFCSENAPGAVRVLLPLETSPSVLTTAKSITTRLATEKACSWLSSNITTLLKREWKSAFERVMKSVPSPLSVDAEEAEGLSRSQQVQKSASGLSAGSTCVPGCAHKVPLGSEVMIEIKDVLSVAVGPRSDDEVFTVRQIESVLDRVGQTLGCRKRLSPVVEQMLLRCTVQLACKLVSGELPLVSSAEGNKRPDLLERFLVLWSWTPAPPLHLLLTEPTLTAIFTATDRERTDYLFLIRQLIERGLLGEQEVGTNWAKLSALSWPEESVEKFQQLSLATQFSMPQLPNHRDLLQVSQ", "length": 1288, "header": "tr|A0A8N7UT82-1|A0A8N7UT82_DANRE Isoform 1 of Codanin-1 OS=Danio rerio OX=7955 GN=cdan1 PE=1 SV=1 CANONICAL=A0A8N7UT82-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 259, "start_aa": "Thr", "end_pos": 259, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr259", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 891, "start_aa": "Thr", "end_pos": 891, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr891", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:565314", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565314", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LK58-1", "protein_name": "Codanin 1", "gene_name": "Cdan1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCFPRGMLLQSLLPACPGCRPAPRALLCQPLPGRPPCGLSRWRPALSADPLAPRPLLLPQDSSEVAALSALRPLRKEFVPFLLNFLREQSSRVLPQGPSTPAKTPGASAALPARQGAPPRGGRGARSQLFPATEPLSTSAEAPLARRAGRRRGPGPSRERGGRGSGGPEEGASSESPPWAGGRKPKGSGSPGSPRLSLSDPPNLSNLEEFPPVGTVPPGSAGRTKPSRRINPTPVSEERSLSKPKTCFTSPPISCVPSSQPSALDTSPWGLGLPPGCRSLQEEREMLRKARSKQLQQSPTPACPAPDSGSPVPNRTGNLTAEPADPARVSSRQRLELVALIYSSCIAENLVPNLFLELFFVLQLLTARRMAATKDSDLESSQGALDSLETPLFRSIHDCVFFAVQVLEHQFQVLSYLDKGTLKLLAENERLLCFSPALQGRLRAAYEGSVAKVSLVIPPSAQAVSFQPETDNRANFSSDRAFHTFKKQRDVFYEVLREWEDHHEEPSWDFEKGLGSRIRAMMGQLSAACSHSHFVRLFQKQLLQMCQSPGGAGGSVLGEAPDVLNMLGADKLGRLRQLQERLIAPQSSGGPCPPPTFPGCQGFFRDFIMSASSFHFNQHLMDSLSLKIRELNGLRLPQHEPGDEDGESDVDWQGERRQFAVVLLSLRLLAKFLGFVAFLPYRGHEPPPTRELQDSILALRSQVPPVLDIRALLQQGLWARRAVLTVPWLVEFLSFADHIVPLLDYYRSVFTLLLHLHRSLVLSKENEGEMCFLNKLLLLAVLGWLFQIPTVPEDLFFLEDGQVDAFEVDTTTSEHGLDSVPVVDQQLLYTCCPYIGELRKLLASWVSGSSGRSGGFVRKITPTTTTSLGTLPLKTSQGLQAQLAEAFFHNQPPSLRRTVEFVAERIGSNCVKHIKATLVADLVHQAESLLQEQLVTRGQEGGDPAQLLEFLCSQLCPHGAQALTQGREFCQKKSPTALRALLPEETPAAVLSSAENIAVGLATEKACSWLSANITALIRREVKAAVSRMLRAQGPEPTARVERRGCSRACEHHAPLPSHLISEIKDVLSLAAGPRDPEEGVSPEHLEQLLNQLGQSLKCRQFLCPTAEQHLAKCSVELASLLVADQIPILGPPTQHRLDRGHARRLLHMLLSLWKDDFQGPVPLQLLLSPRNVGLLADTRPREWDLLLFLLRELVEKDLMGHLEIEACLVSLNEAQWPGDFSEELSTLFRLFLAEPHLLEPQLRACELMQPNRGTVLAQS", "length": 1260 }, "evidence": [ { "id": "RGD:1306771", "url": "https://alliancegenome.org/gene/RGD:1306771#orthology", "database": "AGR" }, { "id": "HGNC:1713", "url": "https://alliancegenome.org/gene/HGNC:1713#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110411-280", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-280#orthology", "database": "AGR" }, { "id": "MGI:1916218", "url": "https://alliancegenome.org/gene/MGI:1916218#orthology", "database": "AGR" }, { "id": "FB:FBgn0024510", "url": "https://alliancegenome.org/gene/FB:FBgn0024510#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CC12-1", "protein_name": "Codanin-1", "gene_name": "Cdan1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVLESLLREEVPVAAAVRWIARSTPSSEDSSEVAALSALRPLRKEFVPFLLNFLREQSSRVLPQGPSTPAKTPVASAALPARQGAPARGGRGARSQLFPAAEPLSAAAEAPLARRAGRRRGPGPGPSRERGGRGSGAAEEGASGESPPWAGGRKPKGSGSPGSPRLSLSDPPNLSNLEEFPPVGTVPPGSAGRTKPSRRINPTPVSEERSLSKPKTCFTSPPISCVPSSQPSTLDTSPWGLGLPPGCRSLQEEREMLRKARTKQLQQSPTPASPIPESGSPVPSRTGNLTAEPADPARVSSRQRLELVALIYSSCIAENLVPNLFLELFFVLQLLTARRMVATKDSDLESSQGALDSLDTPLFRSIHDCVFFAVQVLEHQFQVLSYLDKGTLKLLAENERLLCFSPALQGRLRAAYEGSVAKVSLVIPPSAQAVSFQPETDNRANFSSDRAFHTFKKQRDVFYEVLREWEDHHEEPSWDFEKGLGSRIRAMMGQLSAACSHSHFVRLFQKQLLQMCQSPGGAGGSVLGEAPDVLNMLGADKLGRLRQLQERLIAPQSSGGPCPPPTFPGCQGFFRDFIMSASSFHFNQHLMDSLSLKIRELNGLRLPQHEPGDEDGESDMDWQGERRQFAVVLLSLRLLAKFLGFVAFLPYRGHEPPPTRELQDSILALRSQVPPVLDIRALLQQGLWARRAVLTVPWLVEFLSFADHIVPLLDYYRSVFTLLLRLHRSLVLSKENEGEMCFLNKLLLLAVLGWLFQIPTVPEDLFFLEDGQVDAFEVTTTASEHGLDSVPVVDQQLLYTCCPYIGELRKLLASWVSGSSGRSGGFVRKITPTTTSSLGALPLQTSQGLQAQLAEAFFHNQPPSLRRTVEFVAERIGSNCVKHIKATLVADLVHQAESLLQEQLVARGQEGGDPAQLLESLCSQLCPHGAQALTQGREFCQRKSPTAVRALLPEETPAAVLSSAENIAVGLATEKACSWLSANITALIRREVKAAVSRMLRAQGPEPTARVERRGCSRACEHHAPLPSHLISEIKFHHCSLQDVLSLAAGPRDPEEGVSPEHLEQLLNQMGQSLRCRQFLCPTAEQHLAKCSVELASLLVADQIPILGPPTQHRLERGHARRLLHMLLSLWKDDFQGPVPLQLLLSPRNVGLLADTRPREWDLLLFLLRELVEKDLMGHLEIEACLGRLNEAQWPGDFSEELSTLFRLFLAEPHLLEPQLRACELMQPNRGTVLAQS", "length": 1239 }, "evidence": [ { "id": "RGD:1306771", "url": "https://alliancegenome.org/gene/RGD:1306771#orthology", "database": "AGR" }, { "id": "HGNC:1713", "url": "https://alliancegenome.org/gene/HGNC:1713#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110411-280", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-280#orthology", "database": "AGR" }, { "id": "MGI:1916218", "url": "https://alliancegenome.org/gene/MGI:1916218#orthology", "database": "AGR" }, { "id": "FB:FBgn0024510", "url": "https://alliancegenome.org/gene/FB:FBgn0024510#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWY9-2", "protein_name": "Codanin-1", "gene_name": "CDAN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVLESLLREEVSVAAVVRWIARSTQGSEDNAGEAAALSSLRALRKEFVPFLLNFLREQSSRVLPQGPPTPAKTPGASAALPGRPGGPPRGSRGARSQLFPPTEAQSTAAEAPLARRGGRRRGPGPARERGGRGLEEGVSGESLPGAGGRRLRGSGSPSRPSLTLSDPPNLSNLEEFPPVGSVPPGPTGTKPSRRINPTPVSEERSLSKPKTCFTSPPISCVPSSQPSALDTSPWGLGLPPGCRSLQEEREMLRKERSKQLQQSPTPTCPTPELGSPLPSRTGSLTDEPADPARVSSRQRLELVALVYSSCIAENLVPNLFLELFFVFQLLTARRMVTAKDSDPELSPAVLDSLESPLFQSIHDCVFFAVQVLECHFQVLSNLDKGTLKLLAENERLLCFSPALQGRLRAAYEGSVAKVSLVMPPSTQAVSFQPETDNRANFSSDRAFHTFKKQRDVFYEVLREWEDHHEEPGWDFEKGLGSRIRAMMGQLSAACSHSHFVRLFQKQLLQMCQSPGGAGGTVLGEAPDVLSMLGADKLGRLWRLQERLMAPQSSGGPCPPPTFPGCQGFFRDFILSASSFQFNQHLMDSLSLKIQELNGLALPQHEPNDEDGESDVDWQGERKQFAVVLLSLRLLAKFLGFVAFLPYRGPEPPPTGELQDSILALRSQVPPVLDVRTLLQRGLQARRAVLTVPWLVEFLSFADHVVPLLEYYRDIFTLLLRLHRSLVLSQESEGKMCFLNKLLLLAVLGWLFQIPTVPEDLFFLEEGPSYAFEVDTVAPEHGLDNAPVVDQQLLYTCCPYIGELRKLLASWVSGSSGRSGGFMRKITPTTTTSLGAQPSQTSQGLQAQLAQAFFHNQPPSLRRTVEFVAERIGSNCVKHIKATLVADLVRQAESLLQEQLVTQGEEGGDPAQLLEILCSQLCPHGAQALALGREFCQRKSPGAVRALLPEETPAAVLSSAENIAVGLATEKACAWLSANITALIRREVKAAVSRTLRAQGPEPAARGERRGCSRACEHHAPLPSHLISEIKDVLSLAVGPRDPDEGVSPEHLEQLLGQLGQTLRCRQFLCPPAEQHLAKCSVELASLLVADQIPILGPPAQYRLERGQARRLLHMLLSLWKEDFQGPVPLQLLLSPRNVGLLADTRPREWDLLLFLLRELVEKGLMGRMEIEACLGSLHQAQWPGDFAEELATLSNLFLAEPHLPEPQLRACELVQPNRGTVLAQS", "length": 1227 }, "evidence": [ { "id": "RGD:1306771", "url": "https://alliancegenome.org/gene/RGD:1306771#orthology", "database": "AGR" }, { "id": "HGNC:1713", "url": "https://alliancegenome.org/gene/HGNC:1713#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110411-280", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-280#orthology", "database": "AGR" }, { "id": "MGI:1916218", "url": "https://alliancegenome.org/gene/MGI:1916218#orthology", "database": "AGR" }, { "id": "FB:FBgn0024510", "url": "https://alliancegenome.org/gene/FB:FBgn0024510#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8T626-1", "protein_name": "Protein disks lost", "gene_name": "dlt", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTAELKASDTEMTKPEERHLLQLLAQLEKVPHHQLEQKFVAYFKKVGKGDNQSNCTLEDFATYFLGALRQSTKRYYYSQNSETPVFPLTPIHQLKPPVADVVKEEEQQQLNESSILSRSSCSMSSTSNTTPAPQQPQGRRSTPGSGAQFCSTPNRSGGGGAGGGHSICLGNFLVNTPIQSHQRSKKKITPQKQQQNQHASLGSGTGAGATPQSKPRRRVLPMTISKNVSASSSFGDTSSFSNENNFWRISQSSEIFDRSQEAALEMEARKFLLLKKQEIKSEAPVNVSQQERTPEDEVFPEEAISLEGVANANHLQLLSTIYSLLMDLNLVPNVLRELSFVVHLLNVRDFGQSPVKSYVPSALEGLTQHKSCVYFAAKLLENQKKLLLQLDKRTLSVLLQNERLSLLPQGVVQELETHCQRRQDSTTPFAMDTSSSSQQNVYYHVENDSRDNFPSQNEFGAFKSQRDLFYKALKRWEVSHLNRGFNFPSELGPRIMDIYKKSEHPVNMTHLAKLFVNQLLISATETTESPEELGLKLDPLRHNKLAQRLVTSSSSVEGQFPRSQAFFRDFIAVCSSVAFLVHLKLELFVQLMRNNDSTFDLLQLTDDVAVEEQSAQQGPYIVRVQTMANMLILAKFLGYVTVMPFSGTTQHGNPTPPYLCPQQLQLRNHFRPDFNLREILERSMRQGKLLITLPWLVQYLAMLDLVSLHLPDAVATLELLYGLYADIRMAKLQPAAVFIARSCIGWLLDAQPQLVNGYYNYRAQEAGVGSISAIVDICLKDLSCHDKSHAPLLDELLPVACPFLQEFRVSITPSRQAKSGRFRYITTRLEQLQQNSSSISKDAIVASELSPAEQQQRKLVDAYLQSQNASTRRLIEFVTERTFKCVVKDAQQEILLPSKASADAKVNEIKSTMLEEVFQELHEIFQDARENACQRWKEHVHQMLDRRIEHSLDGLLPSSTNAVLRSTYAHLIRVQAQTQLQQWLQSSVLQSTFYHGDLQELATKVCNCNRNKADAAAAGGGGSSELQLSPDIGFSLSEFLYQLQQWLHCLSLRPEYVGSQEDLAELLRKAQKAVLLPKMPTVFYHLIGSGLVHLLQLLITRKPNFLDKDIISASCSVWRSQQLMDSKASPGIFDGLISISFVQEMANSADSFRMLETILRSMLQSGAIRADHLNELFMPLFAENWSPKVWCMLSELLQQLSLSGKDSEAHYASGDSPEDEAKSHLFMEMLADLSRDLDNF", "length": 1240 }, "evidence": [ { "id": "RGD:1306771", "url": "https://alliancegenome.org/gene/RGD:1306771#orthology", "database": "AGR" }, { "id": "HGNC:1713", "url": "https://alliancegenome.org/gene/HGNC:1713#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110411-280", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-280#orthology", "database": "AGR" }, { "id": "MGI:1916218", "url": "https://alliancegenome.org/gene/MGI:1916218#orthology", "database": "AGR" }, { "id": "FB:FBgn0024510", "url": "https://alliancegenome.org/gene/FB:FBgn0024510#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "primitive erythrocyte differentiation", "id": "GO:0060319", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060319", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UT82", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT82" } ], "pmid": "" }, { "name": "chromatin organization", "id": "GO:0006325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006325", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UT82", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT82" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UT82", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1038, "end_pos": 1040, "annotation": "n_glycosylation_sequon" }, { "start_pos": 220, "end_pos": 222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 475, "end_pos": 477, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 79, "end_pos": 81, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UT82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT82" }, { "id": "PF15296", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15296" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Codanin-1 C-terminal", "eco_id": "ECO_0000259", "start_pos": 846, "end_pos": 959, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 259, 891 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1038, "end_pos": 1040 }, { "start_pos": 220, "end_pos": 222 }, { "start_pos": 475, "end_pos": 477 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 502, "end_pos": 504 }, { "start_pos": 79, "end_pos": 81 }, { "start_pos": 838, "end_pos": 840 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UT85-1", "uniprot_ac": "A0A8N7UT85", "uniprot_id": "A0A8N7UT85_DANRE", "mass": { "chemical_mass": 394251.0, "monoisotopic_mass": 394251.0 }, "refseq": { "ac": "XP_693833", "name": "CUB and sushi domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693833" }, "gene_names": [ { "name": "csmd2", "type": "recommended", "evidence": [ { "id": "A0A8N7UT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT85" } ] }, { "name": "csmd2", "type": "synonym", "evidence": [ { "id": "XP_693833", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693833" } ] } ], "protein_names": [ { "name": "CUB and sushi domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_693833", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693833" }, { "id": "A0A8N7UT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT85/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_693833.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_693833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693833" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UT85", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT85" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "csmd2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT85", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030616-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-39", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00041", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00041", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "565460", "url": "https://www.ncbi.nlm.nih.gov/gene/565460", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000859", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000859", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051277", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051277", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UT85", "url": "https://www.orthodb.org/?gene=A0A8N7UT85", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45656:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45656:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00431", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00431", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_693833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693833", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UT85", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT85", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UT85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT85-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I118", "url": "https://www.uniprot.org/uniprotkb/A0AC58I118", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I118-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I118-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030616-39", "url": "https://zfin.org/ZDB-GENE-030616-39", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSASLNPDRTGLVRTECRCTYNGTRKLDGIRIFALMKVGVQAHHWSGVLFFYMGLLAASVKAQNCSHTLHSPNGTIESPGYPYGYPNYANCTWVIVAQEHNRIQLVFQGFALEEDFDILSVYDGQPSPTNLRTRLTGFQLPAPIVSTGPRLTLWLLSDYAVSGQGFKAVYEALPSYTCGNPGQLLNGMQQGSTFNIGDKIRYSCNQGYVLEGHTVLSCLATSSGTAAWDFPLPYCRADDGCGGTLRGQSGVITSPNYPQEYNNNADCTWTILAEPGDTIALVFSDFQLEEDYDVLEITGTEGSSQWFTGPNLPSPIISSKNWLRLHFTSDGNHKLRGFSAQYQVKKMTELKSRGVKMLPSKDNHSKISVLSQMGVAQGHNMCPDPGIPERGKRKGSDFRRGATVHFSCDEGYELQGSKSITCLRVTDSYVGWSDDRPICRAPMCGGQLRGPSGIITSPNFPVQYDNNANCTWIITASDSSKVIKLTFEEFDLERGYDTLTVGDGSVIGDQRTVFHVLSGTTTPDLVVSTSHQMWLNFKTDDTSGSLGFKVSYEEIDQGGCGDPGIPAYGKREGTGFRHGDKLYFECLPAFELVGKKNITCQKNNQWSAKKPSCVFSCFFNFTTPSGVLLSPNYPQEYGNNMHCVWLIIAKPESRINLAFNDLSMEKQFDFLSIKDGGKAESPILGTFSGDVLPSPITTSGHVARLEFLTDHTYTDRGFNITFTTFRHNECPDPGVPVNGKRFGESLQLGSSISFLCEEGFTKTHGSQTISCILKDGNVVWDNAVPRCEAPCGGNLKASSGIILSPGWPELYKEALNCEWIIEALPGYPIKIIFDKFRTEVNYDVLEVRDGRYPSSPLIGSYQGTQVPQFLISTSNFLYLLFTTDKSHSDIGFRIRYETLQLQSDHCVDPGIPVNGQRHGNDFYVGALVTFSCEAGYTLSDHEPLECEPNFQWSRPLPSCDALCGGFIQGNSGTILSPGFPDFYPHNLNCTWMIETSHGKGVQFTFHTFHLESPHDHLLVTENGSFSQPLWRLTGSTLPPPLSAGLFGNYTAQIRFLSDFSVSYEGFNITFSEYDLEPCEDPGIPPFSTRKGLQFGVGDALIFSCFPGYRLEGPARVVCLGGRRRVWSSPLPRCVAECGSSVTGKQGVLLSPNYPGYYGNDHECIYSIQTQPGKGIQLRARDFHLEEDDMLKVYDGNSNSARLLGTFTGTELMDVTLNSTSSSMWLEFISNSENTSKGFELHFTSFELVKCEDPGVPQFGFKREDKGHFAGSTVSYSCDPGYSLKGPEVLTCLRGERRAWDSPLPQCVAECGGKIKDESMGRILSPGYPAPYEHNLHCVWTIEAALGSTIGLHFLVFHTEEVHDVLRIWDGPQDGGVLLRELSGSTLPPDLHSTFNSVSLQFTTDFFTSKQGFALQFSVSTATSCNDPGIPTNGTRIGDSREPGDHVLFQCDPGYLLQGATKITCTEINNRFFWQPDPPTCSAPCGGNLTGPSGLILSPEYPEPYPHGRECDWTVTVTLDHIISLNFNHFSLEPSYDFLHIYDGPDSLSPLLGSFYGTDVPDRIESSSNTLFLAFRSDASLSSNGFVLQYTENPRESCFEPGLVRNGTRVGTELKLGATVTYYCDSGYTLEGDATLTCIMGSDGKPGWNKPKPVCIAPCGGQYSGLEGVVLSPGYPGNYSSGRTCLYSVVVPRDYVVFSQFAFFQTALNDVVEVYDGPTQHARVLSSLSGAHTGESLPLATSNQILIRFTSKGQSSSRGFHLVYQAVPRTSATQCSSVPEPRHGRRTGNNFAVGAVVSFECNAGYVLEGPSAIECLTVPNALAQWNGSMPSCIVPCGGNLTQRIGTILSPGYPEPYLNSLSCVWKITVPEGMGIQIQVISFVTEQNWDSLEVFDGGDNTDTMLGSFSGTTVPALLNSTSNQLYLHFFSDISVSAAGFRLEYKTVSLTSCPEPVVPMNGFRVGERLQMNNVVSFQCDPGFTLQGVSHISCMPGPVRRWNYPPPLCIAQCGGIREEMEGTILSPGFPGNYPSNGDCTWRIYLPVGYGAHVQFLNFSTEANHDFLEIRNGPFDTSTVIGRFSGQELPSSLLTTSHETTVYFHSDHSQNKPGFRFDYQAYELQECPDPEPFHNGVVVGAGYNVGQSISFECYPGYHLTGHSILTCQHGTTRNWDHPFPRCEVPCGGNITSDNGTIFSPGYPEDYPTSADCSWLITVAPGLGIRLNFTLLQVHGPQDFITVWDGPQETTRKLGVFTEGEPNNPPSSTSNQVLIRFRSSSEKGGLFKINYQAYRLQFCLPPPIIPNAEILMASKEFKIGDIVRYRCLPGYHLNGNSIQTCRLGTHLEFDGPPPSCDITCPMNEVLTASTGVILSQSPGSSLPHFESCSWLVKVDSGYNITFTVEHFQTSRQFDELEIFDGPSRQSPLLISLSGNYSSPLSITSSANKVYLHWSFDHTSSHKGFRIRYSAAYCSSPDPPVNGSLHSQTGTKLGSTLRFNCDRGFNLIGQTTATCYRTPQGIYQWNAPVPLCQVVSCGMPIAPVNGTVIGQHFTLGSRVTFSCNPGFRLANTQPVSTLCQESGRWSPIETRPRCVPVNCPDIGHSAVDHGRWRLIYGMQNKYEAMMMLTCDPGYFYKGQRVIRCQANGTWDYPEPRPSCEIISCGDLGTPPNGNKIGTLTVYGATAIFSCNTGYTLVGSRVRECMSNGLWSGAEVQCLAGHCGTPEPIVNGQIIGENYNYRGSVVYQCNPGFRLIGVSVRICEQDHRWSGKTPVCIPITCGHPGTPANGVTQGTQFNLNDIVRFACNPGYVLQGALKSQCQSNGQWSNALPRCKIVNCTDPGHVENGVRQVLPSGPHRYSFQTAVSYNCNPGYYLLGSSILSCQGDGTWDRSLPKCLLVLCDRPSMPPYAQISGDRRTVGSVIRFSCIGQRSIVGNTTRMCQLDGQWSGSLPHCSGDSAGLCGDPGIPVHGIRLGEEFTTGSVVRFSCEPGYQLKGSSERTCLANGSWVGIQPECHVVSCGNPGTPRNAMIQFHDGLVFSRSITYSCREGYYSTGLLTRHCTVNGTWTGDMPECTVINCGDPGVPANGIRLGSDFTYSHSVSFQCSPGFTMDADRASTLICTKDRTWNGTKPVCKAIVCAAPPSIPNGQVVGSDFQWGSSISYSCNQGYQLSLPTILTCQGSGNWSGERPQCFPVFCGDPGIPAQGKREDRGFTYLSSVSFSCYPPLILVGSARRYCQYDGTWSGTQPSCIDPSHTSCVDPGTPLFGHQNNSQGYQIGSSVYYSCRKGHLLLGSISRTCLPNLTWSGMQPECIAHHCNQPELPAQADVGAIELPSLGYTLIYTCQPGFYLAGGSEHRTCRADGSWTGKPPLCAPDNRPSGKTVGTVQEPPNTKQPVPSGVFAKNSLWRGSYEYLGKKQPAMLSITAFEAFSNRVNGTLMDHSGVQLNLAGIFKKEEAQLLLQVYQIRGPVEIFVNKFKIDNWALDGHVSYMPSSDSFVYQGFVRGKGFGQFGLQRLEGLDPNGENPGYNFASNSSSVAAAILVPFIAMIIAGFALYLYKHRKRPKVPFNGYAGHENTNGRATFENPMYDRNIQPTDIMANETEFTVSTVCTAV", "length": 3604, "header": "tr|A0A8N7UT85-1|A0A8N7UT85_DANRE Isoform 1 of CUB and sushi domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=csmd2 PE=3 SV=1 CANONICAL=A0A8N7UT85-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UT85-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT85/entry#A0A8N7UT85-1", "sequence": { "sequence": "MSASLNPDRTGLVRTECRCTYNGTRKLDGIRIFALMKVGVQAHHWSGVLFFYMGLLAASVKAQNCSHTLHSPNGTIESPGYPYGYPNYANCTWVIVAQEHNRIQLVFQGFALEEDFDILSVYDGQPSPTNLRTRLTGFQLPAPIVSTGPRLTLWLLSDYAVSGQGFKAVYEALPSYTCGNPGQLLNGMQQGSTFNIGDKIRYSCNQGYVLEGHTVLSCLATSSGTAAWDFPLPYCRADDGCGGTLRGQSGVITSPNYPQEYNNNADCTWTILAEPGDTIALVFSDFQLEEDYDVLEITGTEGSSQWFTGPNLPSPIISSKNWLRLHFTSDGNHKLRGFSAQYQVKKMTELKSRGVKMLPSKDNHSKISVLSQMGVAQGHNMCPDPGIPERGKRKGSDFRRGATVHFSCDEGYELQGSKSITCLRVTDSYVGWSDDRPICRAPMCGGQLRGPSGIITSPNFPVQYDNNANCTWIITASDSSKVIKLTFEEFDLERGYDTLTVGDGSVIGDQRTVFHVLSGTTTPDLVVSTSHQMWLNFKTDDTSGSLGFKVSYEEIDQGGCGDPGIPAYGKREGTGFRHGDKLYFECLPAFELVGKKNITCQKNNQWSAKKPSCVFSCFFNFTTPSGVLLSPNYPQEYGNNMHCVWLIIAKPESRINLAFNDLSMEKQFDFLSIKDGGKAESPILGTFSGDVLPSPITTSGHVARLEFLTDHTYTDRGFNITFTTFRHNECPDPGVPVNGKRFGESLQLGSSISFLCEEGFTKTHGSQTISCILKDGNVVWDNAVPRCEAPCGGNLKASSGIILSPGWPELYKEALNCEWIIEALPGYPIKIIFDKFRTEVNYDVLEVRDGRYPSSPLIGSYQGTQVPQFLISTSNFLYLLFTTDKSHSDIGFRIRYETLQLQSDHCVDPGIPVNGQRHGNDFYVGALVTFSCEAGYTLSDHEPLECEPNFQWSRPLPSCDALCGGFIQGNSGTILSPGFPDFYPHNLNCTWMIETSHGKGVQFTFHTFHLESPHDHLLVTENGSFSQPLWRLTGSTLPPPLSAGLFGNYTAQIRFLSDFSVSYEGFNITFSEYDLEPCEDPGIPPFSTRKGLQFGVGDALIFSCFPGYRLEGPARVVCLGGRRRVWSSPLPRCVAECGSSVTGKQGVLLSPNYPGYYGNDHECIYSIQTQPGKGIQLRARDFHLEEDDMLKVYDGNSNSARLLGTFTGTELMDVTLNSTSSSMWLEFISNSENTSKGFELHFTSFELVKCEDPGVPQFGFKREDKGHFAGSTVSYSCDPGYSLKGPEVLTCLRGERRAWDSPLPQCVAECGGKIKDESMGRILSPGYPAPYEHNLHCVWTIEAALGSTIGLHFLVFHTEEVHDVLRIWDGPQDGGVLLRELSGSTLPPDLHSTFNSVSLQFTTDFFTSKQGFALQFSVSTATSCNDPGIPTNGTRIGDSREPGDHVLFQCDPGYLLQGATKITCTEINNRFFWQPDPPTCSAPCGGNLTGPSGLILSPEYPEPYPHGRECDWTVTVTLDHIISLNFNHFSLEPSYDFLHIYDGPDSLSPLLGSFYGTDVPDRIESSSNTLFLAFRSDASLSSNGFVLQYTENPRESCFEPGLVRNGTRVGTELKLGATVTYYCDSGYTLEGDATLTCIMGSDGKPGWNKPKPVCIAPCGGQYSGLEGVVLSPGYPGNYSSGRTCLYSVVVPRDYVVFSQFAFFQTALNDVVEVYDGPTQHARVLSSLSGAHTGESLPLATSNQILIRFTSKGQSSSRGFHLVYQAVPRTSATQCSSVPEPRHGRRTGNNFAVGAVVSFECNAGYVLEGPSAIECLTVPNALAQWNGSMPSCIVPCGGNLTQRIGTILSPGYPEPYLNSLSCVWKITVPEGMGIQIQVISFVTEQNWDSLEVFDGGDNTDTMLGSFSGTTVPALLNSTSNQLYLHFFSDISVSAAGFRLEYKTVSLTSCPEPVVPMNGFRVGERLQMNNVVSFQCDPGFTLQGVSHISCMPGPVRRWNYPPPLCIAQCGGIREEMEGTILSPGFPGNYPSNGDCTWRIYLPVGYGAHVQFLNFSTEANHDFLEIRNGPFDTSTVIGRFSGQELPSSLLTTSHETTVYFHSDHSQNKPGFRFDYQAYELQECPDPEPFHNGVVVGAGYNVGQSISFECYPGYHLTGHSILTCQHGTTRNWDHPFPRCEVPCGGNITSDNGTIFSPGYPEDYPTSADCSWLITVAPGLGIRLNFTLLQVHGPQDFITVWDGPQETTRKLGVFTEGEPNNPPSSTSNQVLIRFRSSSEKGGLFKINYQAYRLQFCLPPPIIPNAEILMASKEFKIGDIVRYRCLPGYHLNGNSIQTCRLGTHLEFDGPPPSCDITCPMNEVLTASTGVILSQSPGSSLPHFESCSWLVKVDSGYNITFTVEHFQTSRQFDELEIFDGPSRQSPLLISLSGNYSSPLSITSSANKVYLHWSFDHTSSHKGFRIRYSAAYCSSPDPPVNGSLHSQTGTKLGSTLRFNCDRGFNLIGQTTATCYRTPQGIYQWNAPVPLCQVVSCGMPIAPVNGTVIGQHFTLGSRVTFSCNPGFRLANTQPVSTLCQESGRWSPIETRPRCVPVNCPDIGHSAVDHGRWRLIYGMQNKYEAMMMLTCDPGYFYKGQRVIRCQANGTWDYPEPRPSCEIISCGDLGTPPNGNKIGTLTVYGATAIFSCNTGYTLVGSRVRECMSNGLWSGAEVQCLAGHCGTPEPIVNGQIIGENYNYRGSVVYQCNPGFRLIGVSVRICEQDHRWSGKTPVCIPITCGHPGTPANGVTQGTQFNLNDIVRFACNPGYVLQGALKSQCQSNGQWSNALPRCKIVNCTDPGHVENGVRQVLPSGPHRYSFQTAVSYNCNPGYYLLGSSILSCQGDGTWDRSLPKCLLVLCDRPSMPPYAQISGDRRTVGSVIRFSCIGQRSIVGNTTRMCQLDGQWSGSLPHCSGDSAGLCGDPGIPVHGIRLGEEFTTGSVVRFSCEPGYQLKGSSERTCLANGSWVGIQPECHVVSCGNPGTPRNAMIQFHDGLVFSRSITYSCREGYYSTGLLTRHCTVNGTWTGDMPECTVINCGDPGVPANGIRLGSDFTYSHSVSFQCSPGFTMDADRASTLICTKDRTWNGTKPVCKAIVCAAPPSIPNGQVVGSDFQWGSSISYSCNQGYQLSLPTILTCQGSGNWSGERPQCFPVFCGDPGIPAQGKREDRGFTYLSSVSFSCYPPLILVGSARRYCQYDGTWSGTQPSCIDPSHTSCVDPGTPLFGHQNNSQGYQIGSSVYYSCRKGHLLLGSISRTCLPNLTWSGMQPECIAHHCNQPELPAQADVGAIELPSLGYTLIYTCQPGFYLAGGSEHRTCRADGSWTGKPPLCAPDNRPSGKTVGTVQEPPNTKQPVPSGVFAKNSLWRGSYEYLGKKQPAMLSITAFEAFSNRVNGTLMDHSGVQLNLAGIFKKEEAQLLLQVYQIRGPVEIFVNKFKIDNWALDGHVSYMPSSDSFVYQGFVRGKGFGQFGLQRLEGLDPNGENPGYNFASNSSSVAAAILVPFIAMIIAGFALYLYKHRKRPKVPFNGYAGHENTNGRATFENPMYDRNIQPTDIMANETEFTVSTVCTAV", "length": 3604, "header": "tr|A0A8N7UT85-1|A0A8N7UT85_DANRE Isoform 1 of CUB and sushi domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=csmd2 PE=3 SV=1 CANONICAL=A0A8N7UT85-1" }, "locus": {} }, { "isoform_ac": "A0AC58I118-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT85/entry#A0AC58I118-1", "sequence": { "sequence": "MQQGSTFNIGDKIRYSCNQGYVLEGHTVLSCLATSSGTAAWDFPLPYCRADDGCGGTLRGQSGVITSPNYPQEYNNNADCTWTILAEPGDTIALVFSDFQLEEDYDVLEITGTEGSSQWFTGPNLPSPIISSKNWLRLHFTSDGNHKLRGFSAQYQVKKMTELKSRGVKMLPSKDNHSKISVLSQMGVAQGHNMCPDPGIPERGKRKGSDFRRGATVHFSCDEGYELQGSKSITCLRVTDSYVGWSDDRPICRAPMCGGQLRGPSGIITSPNFPVQYDNNANCTWIITASDSSKVIKLTFEEFDLERGYDTLTVGDGSVIGDQRTVFHVLSGTTTPDLVVSTSHQMWLNFKTDDTSGSLGFKVSYEEIDQGGCGDPGIPAYGKREGTGFRHGDKLYFECLPAFELVGKKNITCQKNNQWSAKKPSCVFSCFFNFTTPSGVLLSPNYPQEYGNNMHCVWLIIAKPESRINLAFNDLSMEKQFDFLSIKDGGKAESPILGTFSGDVLPSPITTSGHVARLEFLTDHTYTDRGFNITFTTFRHNECPDPGVPVNGKRFGESLQLGSSISFLCEEGFTKTHGSQTISCILKDGNVVWDNAVPRCEAPCGGNLKASSGIILSPGWPELYKEALNCEWIIEALPGYPIKIIFDKFRTEVNYDVLEVRDGRYPSSPLIGSYQGTQVPQFLISTSNFLYLLFTTDKSHSDIGFRIRYETLQLQSDHCVDPGIPVNGQRHGNDFYVGALVTFSCEAGYTLSDHEPLECEPNFQWSRPLPSCDALCGGFIQGNSGTILSPGFPDFYPHNLNCTWMIETSHGKGVQFTFHTFHLESPHDHLLVTENGSFSQPLWRLTGSTLPPPLSAGLFGNYTAQIRFLSDFSVSYEGFNITFSEYDLEPCEDPGIPPFSTRKGLQFGVGDALIFSCFPGYRLEGPARVVCLGGRRRVWSSPLPRCVAECGSSVTGKQGVLLSPNYPGYYGNDHECIYSIQTQPGKGIQLRARDFHLEEDDMLKVYDGNSNSARLLGTFTGTELMDVTLNSTSSSMWLEFISNSENTSKGFELHFTSFELVKCEDPGVPQFGFKREDKGHFAGSTVSYSCDPGYSLKGPEVLTCLRGERRAWDSPLPQCVAECGGKIKDESMGRILSPGYPAPYEHNLHCVWTIEAALGSTIGLHFLVFHTEEVHDVLRIWDGPQDGGVLLRELSGSTLPPDLHSTFNSVSLQFTTDFFTSKQGFALQFSVSTATSCNDPGIPTNGTRIGDSREPGDHVLFQCDPGYLLQGATKITCTEINNRFFWQPDPPTCSAPCGGNLTGPSGLILSPEYPEPYPHGRECDWTVTVTLDHIISLNFNHFSLEPSYDFLHIYDGPDSLSPLLGSFYGTDVPDRIESSSNTLFLAFRSDASLSSNGFVLQYTENPRESCFEPGLVRNGTRVGTELKLGATVTYYCDSGYTLEGDATLTCIMGSDGKPGWNKPKPVCIAPCGGQYSGLEGVVLSPGYPGNYSSGRTCLYSVVVPRDYVVFSQFAFFQTALNDVVEVYDGPTQHARVLSSLSGAHTGESLPLATSNQILIRFTSKGQSSSRGFHLVYQAVPRTSATQCSSVPEPRHGRRTGNNFAVGAVVSFECNAGYVLEGPSAIECLTVPNALAQWNGSMPSCIVPCGGNLTQRIGTILSPGYPEPYLNSLSCVWKITVPEGMGIQIQVISFVTEQNWDSLEVFDGGDNTDTMLGSFSGTTVPALLNSTSNQLYLHFFSDISVSAAGFRLEYKTVSLTSCPEPVVPMNGFRVGERLQMNNVVSFQCDPGFTLQGVSHISCMPGPVRRWNYPPPLCIAQCGGIREEMEGTILSPGFPGNYPSNGDCTWRIYLPVGYGAHVQFLNFSTEANHDFLEIRNGPFDTSTVIGRFSGQELPSSLLTTSHETTVYFHSDHSQNKPGFRFDYQAYELQECPDPEPFHNGVVVGAGYNVGQSISFECYPGYHLTGHSILTCQHGTTRNWDHPFPRCEVPCGGNITSDNGTIFSPGYPEDYPTSADCSWLITVAPGLGIRLNFTLLQVHGPQDFITVWDGPQETTRKLGVFTEGEPNNPPSSTSNQVLIRFRSSSEKGGLFKINYQAYRLQFCLPPPIIPNAEILMASKEFKIGDIVRYRCLPGYHLNGNSIQTCRLGTHLEFDGPPPSCDITCPMNEVLTASTGVILSQSPGSSLPHFESCSWLVKVDSGYNITFTVEHFQTSRQFDELEIFDGPSRQSPLLISLSGNYSSPLSITSSANKVYLHWSFDHTSSHKGFRIRYSAAYCSSPDPPVNGSLHSQTGTKLGSTLRFNCDRGFNLIGQTTATCYRTPQGIYQWNAPVPLCQVVSCGMPIAPVNGTVIGQHFTLGSRVTFSCNPGFRLANTQPVSTLCQESGRWSPIETRPRCVPVNCPDIGHSAVDHGRWRLIYGMQNKYEAMMMLTCDPGYFYKGQRVIRCQANGTWDYPEPRPSCEIISCGDLGTPPNGNKIGTLTVYGATAIFSCNTGYTLVGSRVRECMSNGLWSGAEVQCLAGHCGTPEPIVNGQIIGENYNYRGSVVYQCNPGFRLIGVSVRICEQDHRWSGKTPVCIPITCGHPGTPANGVTQGTQFNLNDIVRFACNPGYVLQGALKSQCQSNGQWSNALPRCKIVNCTDPGHVENGVRQVLPSGPHRYSFQTAVSYNCNPGYYLLGSSILSCQGDGTWDRSLPKCLLVLCDRPSMPPYAQISGDRRTVGSVIRFSCIGQRSIVGNTTRMCQLDGQWSGSLPHCSGDSAGLCGDPGIPVHGIRLGEEFTTGSVVRFSCEPGYQLKGSSERTCLANGSWVGIQPECHVVSCGNPGTPRNAMIQFHDGLVFSRSITYSCREGYYSTGLLTRHCTVNGTWTGDMPECTVINCGDPGVPANGIRLGSDFTYSHSVSFQCSPGFTMDADRASTLICTKDRTWNGTKPVCKAIVCAAPPSIPNGQVVGSDFQWGSSISYSCNQGYQLSLPTILTCQGSGNWSGERPQCFPVFCGDPGIPAQGKREDRGFTYLSSVSFSCYPPLILVGSARRYCQYDGTWSGTQPSCIDPSHTSCVDPGTPLFGHQNNSQGYQIGSSVYYSCRKGHLLLGSISRTCLPNLTWSGMQPECIAHHCNQPELPAQADVGAIELPSLGYTLIYTCQPGFYLAGGSEHRTCRADGSWTGKPPLCAPDNRPSGKTVGTVQEPPNTKQPVPSGVFAKNSLWRGSYEYLGKKQPAMLSITAFEAFSNRVNGTLMDHSGVQLNLAGIFKKEEAQLLLQVYQIRGPVEIFVNKFKIDNWALDGHVSYMPSSDSFVYQGFVRGKGFGQFGLQRLEGLDPNGENPGYNFASNSSSVAAAILVPFIAMIIAGFALYLYKHRKRPKVPFNGYAGHENTNGRATFENPMYDRNIQPTDIMANETEFTVSTVCTAV", "length": 3417, "header": "tr|A0AC58I118-1|A0AC58I118_DANRE Computationally mapped isoform of CUB and sushi domain-containing protein 2 isoform X2 OS=Danio rerio OX=7955 GN=csmd2 PE=3 SV=1 CANONICAL=A0A8N7UT85-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K6F2-1", "protein_name": "CUB and Sushi multiple domains 2", "gene_name": "Csmd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPRSRGPEQGCCGCPAGRARGEIGIWALVPGTGSRWGRPPPPPPPPPPPPPLLLLLGWGLLSASAAAGQNCTFHLQGPNGTVESPGFPYGYPNYANCTWTITAEDQHRIQLVFQSFALEEDFDVLSVFDGPPQAENLRTRLTGFQLPATIVSAASTLSLSLISDYAVSAQGFRASYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNPGFFLEGHAVLTCHASSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPAEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSKDNNQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCSEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPAKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTHHQMWLLFQSDSSGSSLGFKASYEEIEQGSCGDPGIPAYGQREGSRFRHGDTLKFECQPAFELVGQKSITCQKNNQWSAKKPGCVFSCFFNFTSPSGIVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNCLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWVIETSHGKGVFFTFHTFHLESGHDYLLITENGSFSQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKAKAFELAEGDLLKVYDGSNNSARLLGVFSRSEMLGVTLNSTSSSLWLDFITDAENTSKGFELQFSSFELIRCEDPGTPQFGYKVHDGGHFAGSSVTFSCDPGYSLRGSEELMCLSGERRTWDRPLPTCVAECGGTVRGEASGQVLSPGYPAPYEHNLNCIWTIEADAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGSMLPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGVPQNGSRSGDSWEAGDTTVFQCDPGYALQGSAEISCVKIQNRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNTFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPSRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSITYYCHGGYEVEGASTLSCILGPDKKPMWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQTCLYFVTVPKDYVVFGQFAFFHTALNDIVEVHDGYSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGQASAKGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIIRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWRIMVPEGAGIQIQVISFVTEQNWDSLEVFDGADNTVNMLGSFSGATVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGAVEEMEGVILSPGFPGNYPSNMDCSWKISLPVGFGAHIQFLNFSTEPNHDFLEIRSGPSETSRMMGRFSGSELPGSLLSTSHDTIVYFHSDHSQNRPGFKLEYQAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGQPVLTCQHGTNRNWDHPLPRCEVPCGGNITSFNGTVYSPGYPSPYSSSQDCVWQITVPIGHGVHLNLSLLQIEPFGDYITVWDGPQQTSLQLGVFTRSLSKKIAYSSSNQVLLKFHRDTATGGIFAIAFTAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGSEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPEYNVSITVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPKAPLHGFILGQTTTQPGGSIHFGCNTGYRLVGHSMAICTRHPQGYHLWSEAIPLCQAISCGLPAAPKNGIVFGKEYTVGTKAVYSCNEGYHLQTGAEATTECLDTGLWSNSNVPPQCVPVTCPDISSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGRWSLGESMPTCQIISCGELPTPPSGHRIGTMSVYGATAIFSCNSGYTLVGSRVRECMSNGLWSGSEVRCLAGHCGTPEPIVNGHINGENFNYRGSVVYQCRAGFRLIGMSVRICQQDHHWSGKTPFCVPITCGHPGNPVNGLTQGSQFNLNDVVKFVCNPGYMAEGAARSQCLASGQWSDTLPTCRIINCTDPGHQENSVRQVHASGPHRFSFGTTVSYQCNHGFYLLGAPALSCQGDGTWDRPRPQCLLVSCGHPGSPPHAQMSGDSYIVGAVVRYSCTGKRTLVGNATRMCGLDGHWTGSLPHCSGTSTGVCGDPGIPAHGIRLGDSFAPGSLIRFSCEAGHMLRGSSERVCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYSTGLLSRHCSVNGTWTGSDPECTVINCGDPGIPANGIRLGNDFRYNKTVTYQCVPGYVMESRRVSVLGCTKDRTWNGTKPVCKAIMCKPPQLIPNGKVVGSDFTWGSSVSYACLEGYQLSLPAVLTCEGNGSWTGELPQCFPVFCGDPGVPPRGRREDRGFSYRSSVSFSCHAPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGMPQFGIQNSSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCKQPETPTHANVGALDLPSVGYTLIYSCQEGFSLRGGSEHRTCKADGSWTGKPPICLAEVRPSGRPINTAREPLLTQASVPGDVFAKNSLWKGAYEYQGKKQPAMLRVISFQVANSKVNATMIDHSGVELHLAGNYKKEDFRLLLQAYQVTGPAESFVNKFKDDHWALDGHVSSESSGGTFVYQGSVKGQGFGQFGFQRLDLKLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKHRRRPKVPFNGYAGHENTNVRATFENPMYDRNIQTTDIMSNEAEFTVSTVCTAV", "length": 3612 }, "evidence": [ { "id": "RGD:1565728", "url": "https://alliancegenome.org/gene/RGD:1565728#orthology", "database": "AGR" }, { "id": "MGI:2386401", "url": "https://alliancegenome.org/gene/MGI:2386401#orthology", "database": "AGR" }, { "id": "HGNC:19290", "url": "https://alliancegenome.org/gene/HGNC:19290#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-39#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A8JUX3-1", "protein_name": "Furrowed", "gene_name": "CT26106", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHRTQPSLPLPLPLLALALALASALAFAQAQNIDAGCSFPGSPAHSSVVFSNANLTQGTVASYSCERGFELLGPARRVCDKGQWVPEGIPFCVLNVAAGKAPMQISTDGAGAPQKAIDGSTSAFFTPETCSLTKAERSPWWYVNLLEPYMVQLVRLDFGKSCCGNKPATIVVRVGNNRPDLGTNPICNRFTGLLEAGQPLFLPCNPPMPGAFVSVHLENSTPNPLSICEAFVYTDQALPIERCPTFRDQPPGALASYNGKCYIFYNRQPLNFLDALSFCRSRGGTLISESNPALQGFISWELWRRHRSDVSSQYWMGAVRDGSDRSSWKWVNGDELTVSFWSHPGGDEDCARFDGSKGWLWSDTNCNTLLNFICQHQPKTCGRPEQPPNSTMVALNGFEVGAQIKYSCDANHLLVGPATRTCLETGFYNEFPPVCKYIECGLPASIAHGSYALLNNTVGYLSLVKYSCEEGYEMIGRALLTCDFDERWNGPPPRCEIVECDTLPGNYYSTIINAPNGTYYGSKAEISCPPGYRMEGPRVLTCLASGQWSSALPRCIKLEPSTQPTAASTIPVPSSVATPPPFRPKVVSSTTSRTPYRPAVSTASSGIGGSSTSTVGTYPSLSPTQVEINGESESEEEINVPPVPGTVREEFPPRRTVRPVLIPKKPNSTPAALPPTTHQVPPQPPSTYAPTPPRSSRPSGAPNSAGEVETTTRNTQQIIANSHPQDNEIPDSVNIQQNQSPNVNVPFAVDNPDRKETKEAKLNLGAIVALGAFGGFVFLAAVITTIVILVRSTPNSQRRHLAKHLTAYQHHHAHHHHHQQIQQQFHHRNQQQQQQEQHHQNHTRQQQQKYHQQQEQLHQSHRQKKQPSQSKKGQGGIGIGIGIGIPRPSRLPSYATATATSATSYASTAQLTQSHLFPDGGGYGSVGSSSAGGLVHAPSMWYSVLALPFDDQKLGRREFSSYGRGYRARAGLFSNSHINRTTQHYRHRASPDCNTVASFDSSTSGSRNGLNRYYRQAWENLHESASKNSSHNALRRKETLDPPSMTRSRDNLRDNMQRSRENLDRCGRDNYGMRDDSEMVVSSVVSDVCLKGEKKRHHHHHHKSSSRNGDYRDRDHSSGRREHHRHSGGGGGGGGGGGGHY", "length": 1141 }, "evidence": [ { "id": "RGD:1565728", "url": "https://alliancegenome.org/gene/RGD:1565728#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7Z408-1", "protein_name": "CUB and sushi domain-containing protein 2", "gene_name": "CSMD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRLISIAPGPRWQVQSHHPRSAGQNCTFQLHGPNGTVESPGFPYGYPNYANCTWTITAEEQHRIQLVFQSFALEEDFDVLSVFDGPPQPENLRTRLTGFQLPATIVSAATTLSLRLISDYAVSAQGFHATYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNLGFFLEGHAVLTCHAGSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPSEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSKDNSQKTSVLTQVGVSQGHNMCPDPGIPERGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPSKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTNHQMWLLFQTDGSGSSLGFKASYEEIEQGSCGDPGIPAYGRREGSRFHHGDTLKFECQPAFELVGQKAITCQKNNQWSAKKPGCVFSCFFNFTSPSGVVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSRALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWIIETSHGKGVFFTFHTFHLESGHDYLLITENGSFTQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKARAFELSEGDVLKVYDGNNNSARLLGVFSHSEMMGVTLNSTSSSLWLDFITDAENTSKGFELHFSSFELIKCEDPGTPKFGYKVHDEGHFAGSSVSFSCDPGYSLRGSEELLCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEAEAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPALPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGIPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIENRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNIFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPGRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGTSTLSCILGPDGKPVWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQICLYFVTVPKDYVVFGQFAFFHTALNDVVEVHDGHSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGLAPARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIVRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIVVPEGAGIQIQVVSFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGTVEEMEGVILSPGFPGNYPSNMDCSWKIALPVGFGAHIQFLNFSTEPNHDYIEIRNGPYETSRMMGRFSGSELPSSLLSTSHETTVYFHSDHSQNRPGFKLEYQDLTYSHQISSFLRGFDLSELERTNSTPPVAASYVWDLDPGCEAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGHPVLTCQHGTNRNWDHPLPKCEVPCGGNITSSNGTVYSPGFPSPYSSSQDCVWLITVPIGHGVRLNLSLLQTEPSGDFITIWDGPQQTAPRLGVFTRSMAKKTVQSSSNQVLLKFHRDAATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGNEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPDYNISLTVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPRAPLHGFILGQTSTQPGGSIHFGCNAGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPEAPKNGMVFGKEYTVGTKAMYSCSEGYHLQAGAEATAECLDTGLWSNRNVPPQCVPVTCPDVSSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGKWSLGDSTPTCRIISCGELPIPPNGHRIGTLSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENYSYRGSVVYQCNAGFRLIGMSVRICQQDHHWSGKTPFCVLVSCGHPGSPPHSQMSGDSYTVGAVVRYSCIGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSVGVCGDPGIPAHGIRLGDSFDPGTVMRFSCEAGHVLRGSSERTCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSIVYECREGYYATGLLSRHCSVNGTWTGSDPECLVINCGDPGIPANGLRLGNDFRYNKTVTYQCVPGYMMESHRVSVLSCTKDRTWNGTKPVCKALMCKPPPLIPNGKVVGSDFMWGSSVTYACLEGYQLSLPAVFTCEGNGSWTGELPQCFPVFCGDPGVPSRGRREDRGFSYRSSVSFSCHPPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGVPQFGIQNNSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCRQPETPTHANVGALDLPSMGYTLIYSCQEGFSLKGGSEHRTCKADGSWTGKPPICLEVRPSGRPINTAREPPLTQALIPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVANSKVNATMIDHSGVELHLAGTYKKEDFHLLLQVYQITGPVEIFMNKFKDDHWALDGHVSSESSGATFIYQGSVKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKHRRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMASEAEFTVSTVCTAV", "length": 3487 }, "evidence": [ { "id": "RGD:1565728", "url": "https://alliancegenome.org/gene/RGD:1565728#orthology", "database": "AGR" }, { "id": "MGI:2386401", "url": "https://alliancegenome.org/gene/MGI:2386401#orthology", "database": "AGR" }, { "id": "HGNC:19290", "url": "https://alliancegenome.org/gene/HGNC:19290#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-39#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "V9GX34-1", "protein_name": "CUB and Sushi multiple domains 2", "gene_name": "Csmd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPRSRGPEQGCCGCPAVRARGEIGIWALVPGTGSRWGRPPPPPPPPPPPPPLLLLLGWGLLSASAAAGQNCTFHLQGPNGTVESPGFPYGYPNYANCTWTITAEDQHRIQLVFQSFALEEDFDVLSVFDGPPQAENLRTRLTGFQLPATIVSAASTLSLSLISDYAVSAQGFRASYEVLPSHTCGNPGRLPNGIQQGSTFNLGDKVRYSCNPGFFLEGHAVLTCHASSENSATWDFPLPSCRADDACGGTLRGQSGIISSPHFPAEYHNNADCTWTILAELGDTIALVFIDFQLEDGYDFLEVTGTEGSSLWFTGASLPAPVISSKNWLRLHFTSDGNHRQRGFSAQYQVKKQIELKSRGVKLMPSKDNNQKTSVLTQVGVSQGHNMCPDPGIPEKGKRLGSDFRLGSSVQFTCNEGYDLQGSKRITCMKVSDMFAAWSDHRPVCRARMCDAHLRGPSGIITSPNFPIQYDNNAHCVWIITALNPAKVIKLAFEEFDLERGYDTLTVGDGGQDGDQKTVLYILTGTSVPDLIVSTHHQMWLLFQSDSSGSSLGFKASYEEIEQGSCGDPGIPAYGQREGSRFRHGDTLEFECQPAFELVGQKSITCQKNNQWSAKKPGCVFSCFFNFTSPSGIVLSPNYPEDYGNHLHCVWLILARPESRIHLAFNDIDVEPQFDFLVIKDGATAEAPVLGTFSGNQLPSSITSSGHVARLEFQTDHSTGKRGFNITFTTFRHNECPDPGVPVNGKRFGDSLQLGSSISFLCDEGFLGTQGSETITCVLKEGSVVWNSAVLRCEAPCGGHLTSPSGTILSPGWPGFYKDALSCAWVIEAQPGYPIKITFDRFKTEVNYDTLEVRDGRTYSAPLIGVYHGTQVPQFLISTSNYLYLLFSTDKSHSDIGFQLRYETITLQSDHCLDPGIPVNGQRHGNDFYVGALVTFSCDSGYTLSDGEPLECEPNFQWSHALPSCEALCGGFIQGSSGTILSPGFPDFYPNNLNCTWVIETSHGKGVFFTFHTFHLESGHDYLLITENGSFSQPLRQLTGSRLPAPISAGLYGNFTAQVRFISDFSMSYEGFNITFSEYDLEPCEEPEVPAYSIRKGLQFGVGDTLTFSCFPGYRLEGTARITCLGGRRRLWSSPLPRCVAECGNSVTGTQGTLLSPNFPVNYNNNHECIYSIQTQPGKGIQLKAKAFELAEGDLLKVYDGTNNSARLLGVFSRSEMLGVTLNSTSSSLWLDFITDAENTSKGFELQFSSFELIRCEDPGTPQFGYKVHDGGHFAGSSVTFSCDPGYSLRGSEELMCLSGERRTWDRPLPTCVAECGGTVRGEVSGQVLSPGYPAPYEHNLNCIWTIEADAGCTIGLHFLVFDTEEVHDVLRIWDGPVESGVLLKELSGPMLPKDLHSTFNSVVLQFSTDFFTSKQGFAIQFSVSTATSCNDPGVPQNGSRSGDSWEAGDSTVFQCDPGYALQGSAEISCVKIQNRFFWQPSPPTCIAPCGGDLTGPSGVILSPNYPEPYPPGKECDWKVTVSPDYVIALVFNTFNLEPGYDFLHIYDGRDSLSPLIGSFYGSQLPSRIESSSNSLFLAFRSDASVSNAGFVIDYTENPRESCFDPGSIKNGTRVGSDLKLGSSVTYYCHGGYEVEGASTLSCILGPDGKPMWNNPRPVCTAPCGGQYVGSDGVVLSPNYPQNYTSGQTCLYFVTVPKDYVVFGQFAFFHTALNDIVEVHDGYSQHSRLLSSLSGSHTGESLPLATSNQVLIKFSAKGQVSARGFHFVYQAVPRTSATQCSSVPEPRYGKRLGSDFSVGAIIRFECNSGYALQGSPEIECLPVPGALAQWNVSAPTCVVPCGGNLTERRGTILSPGFPEPYLNSLNCVWKIMVPEGAGIQIQVISFVTEQNWDSLEVFDGADNTVTMLGSFSGTTVPALLNSTSNQLYLHFYSDISVSAAGFHLEYKTVGLSSCPEPAVPSNGVKTGERYLVNDVVSFQCEPGYALQGHAHISCMPGTVRRWNYPPPLCIAQCGGAVEEMEGVILSPGFPGNYPSNMDCSWKISLPVGFGAHIQFLNFSTEPNHDFLEIRSGPSETSRMMGRFSGSELPGSLLSTSHDSIVYFHSDHSQNRPGFKLEYQAYELQECPDPEPFANGIVRGAGYNVGQSVTFECLPGYQLTGQPVLTCQHGTNRNWDHPLPRCEVPCGGNITSFNGTVYSPGYPSPYSSSQDCVWQITVPIGHGVHLNLSLLQIEPFGDYITVWDGPQQTSLQLGVFTRSLSKKIAHSSSNQVLLKFHRDTATGGIFAIAFSAYPLTKCPPPTILPNAEVVTENEEFNIGDIVRYRCLPGFTLVGSEILTCKLGTYLQFEGPPPICEVHCPTNELLTDSTGVILSQSYPGSYPQFQTCSWLVRVEPEYNISITVEYFLSEKQYDEFEIFDGPSGQSPLLKALSGNYSAPLIVTSSSNSVYLRWSSDHAYNRKGFKIRYSAPYCSLPKAPLHGFILGQTTTQPGGSIHFGCNTGYRLVGHSMAICTRHPQGYHLWSEAIPLCQALSCGLPDAPKNGIVFGKEYTVGTKAVYSCNEGYHLQAGAEATAECLDTGLWSNSNVPPQCVPVTCPDISSISVEHGRWRLIFETQYQFQAQLMLICDPGYYYTGQRVIRCQANGRWSLGESMPTCQIISCGELPTPPSGHRIGTMSVYGATAIFSCNSGYTLVGSRVRECMANGLWSGSEVRCLAGHCGTPEPIVNGHINGENFNYRGSVVYQCRAGFRLIGMSVRICQQDHHWSGKTPFCVPITCGHPGNPVNGLTQGSQFNLNDVVKFICNPGYIAEGAARSQCLASGQWSDTLPTCRIINCTDPGHQENSVRQVHTSGPHRFSFGTTVSYQCNHGFYLLGTPALSCQGDGTWDRPRPQCLLVSCGHPGSPPHAQMSGDSYIVGAVVRYSCTGKRTLVGNSTRMCGLDGHWTGSLPHCSGTSTGVCGDPGIPAHGIRLGDSFAPGSVMRFSCDAGHVLRGSSERMCQANGSWSGSQPECGVISCGNPGTPSNARVVFSDGLVFSSSVVYECREGYYATGLLSRHCSVNGTWTGSDPECTVINCGDPGIPANGIRLGNDFRYNKTVTYQCVPGYVMESHRVSVLSCTKDRTWNGTKPVCKAIMCKPPQLIPNGKVVGSDFTWGSSVSYACLEGYQLSLPAVLTCEGNGSWTGELPQCFPVFCGDPGVPPRGRREDRGFSYRSSVSFSCHAPLVLVGSPRRFCQSDGTWSGTQPSCIDPTLTTCADPGMPQFGIQNSSQGYQVGSTVLFRCQKGYLLQGSTTRTCLPNLTWSGTPPDCVPHHCKQPETPTHANVGALDLPSMGYTLIYSCQEGFSLRGGSEHRTCKADGSWTGKPPVCLEVRPSGRPINTAREPMLTQASVPGDVFAKNSLWKGAYEYQGKKQPAMLRVTGFQVANSKVNATMIDHSGVELHLAGNYKKEDFRLLLQVYQVTGPVESFVNKFKDDHWALDGHVSSESSGGTFVYQGSVKGQGFGQFGFQRLDLRLLESDPESIGRHFASNSSSVAAAILVPFIALIIAGFVLYLYKHRRRPKVPFNGYAGHENTNVRATFENPMYDRNIQPTDIMSNEAEFTVSTVCTAV", "length": 3611 }, "evidence": [ { "id": "RGD:1565728", "url": "https://alliancegenome.org/gene/RGD:1565728#orthology", "database": "AGR" }, { "id": "MGI:2386401", "url": "https://alliancegenome.org/gene/MGI:2386401#orthology", "database": "AGR" }, { "id": "HGNC:19290", "url": "https://alliancegenome.org/gene/HGNC:19290#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-39#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UT85", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT85" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1022, "end_pos": 1024, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1048, "end_pos": 1050, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1067, "end_pos": 1069, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1217, "end_pos": 1219, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1233, "end_pos": 1235, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1432, "end_pos": 1434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1487, "end_pos": 1489, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1605, "end_pos": 1607, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1677, "end_pos": 1679, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1825, "end_pos": 1827, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1838, "end_pos": 1840, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1915, "end_pos": 1917, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2051, "end_pos": 2053, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2182, "end_pos": 2184, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2187, "end_pos": 2189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2220, "end_pos": 2222, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2391, "end_pos": 2393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2427, "end_pos": 2429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2473, "end_pos": 2475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2536, "end_pos": 2538, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2638, "end_pos": 2640, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2828, "end_pos": 2830, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2927, "end_pos": 2929, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2996, "end_pos": 2998, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3055, "end_pos": 3057, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3119, "end_pos": 3121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3175, "end_pos": 3177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3261, "end_pos": 3263, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3293, "end_pos": 3295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3426, "end_pos": 3428, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3524, "end_pos": 3526, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3591, "end_pos": 3593, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" }, { "start_pos": 597, "end_pos": 599, "annotation": "n_glycosylation_sequon" }, { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" }, { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" }, { "start_pos": 719, "end_pos": 721, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" }, { "start_pos": 988, "end_pos": 990, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT85" }, { "id": "PS01180", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUB", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 173, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UT85", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UT85" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 176, "end_pos": 237, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1022, "end_pos": 1024 }, { "start_pos": 1048, "end_pos": 1050 }, { "start_pos": 1067, "end_pos": 1069 }, { "start_pos": 1217, "end_pos": 1219 }, { "start_pos": 1233, "end_pos": 1235 }, { "start_pos": 1432, "end_pos": 1434 }, { "start_pos": 1487, "end_pos": 1489 }, { "start_pos": 1605, "end_pos": 1607 }, { "start_pos": 1677, "end_pos": 1679 }, { 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"MSRYRKSGPRLHRHCETCYNRRCKASIEVSVSCMVINCRLLCGASFHLCKEDEHSLLCPNEKVPCINAHYGCPFTMCRSRLAKHLEVCPASIVCCSMEWNRWPVQNPDAPLYPNLLKELHEQESLDLSMALRDQKHLCARLKMRNCFPELMEEREEEPTPVEEEEDEEAAAGREAVPNGISINEHEGSVLLNGPSKSCEKAMNENVVLNGDIDKEKYNLFEKMFSMEKGGCKQAEASKTEEKKGQKAPSVTKPQDAFIEPKNEETNAPSVDVSKCGLAPWQDGVLERLGQEVKPREFNMYIVHHGRMLISFGQMDACTPRERDFVYGSLEPIPVQTLRSFKVPTSYKQKRIQLREFKARVMTEHKCVGTSDESTVSENKDGWEMDEMFATLLCYAESEIRGHKISEMVPTDGLYVDIATQTYNFATAPFKYNASLTEVTADMDLKLHLELDTETATLRHNKFTSAFSFMCGHFFRRDEFASHFKNVHLDIQSCMGGWFEQRCPLAYLGCTFSQKRLQPATQRAKVFYNRDLSIFTLTPEVPACLQNNSPNLSEKAHVKYEDSLSNLPFEVLHHIASYLDSFTLSQLALVSRLFRDICATLLQERGMVAFKWRKKSNSLGGARWKPTIVWEFSTLFSKVENWCIGDTPSMAEHLQNCPFYQTELKTEPFTLTNMSDIKGKGGNNLVSLFMGHK", "length": 692, "header": "tr|A0A8N7UTA2-1|A0A8N7UTA2_DANRE Isoform 1 of F-box only protein 40 isoform X1 OS=Danio rerio OX=7955 GN=fbxo40.2 PE=4 SV=2 CANONICAL=A0A8N7UTA2-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UTA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTA2/entry#A0A8N7UTA2-1", "sequence": { "sequence": "MSRYRKSGPRLHRHCETCYNRRCKASIEVSVSCMVINCRLLCGASFHLCKEDEHSLLCPNEKVPCINAHYGCPFTMCRSRLAKHLEVCPASIVCCSMEWNRWPVQNPDAPLYPNLLKELHEQESLDLSMALRDQKHLCARLKMRNCFPELMEEREEEPTPVEEEEDEEAAAGREAVPNGISINEHEGSVLLNGPSKSCEKAMNENVVLNGDIDKEKYNLFEKMFSMEKGGCKQAEASKTEEKKGQKAPSVTKPQDAFIEPKNEETNAPSVDVSKCGLAPWQDGVLERLGQEVKPREFNMYIVHHGRMLISFGQMDACTPRERDFVYGSLEPIPVQTLRSFKVPTSYKQKRIQLREFKARVMTEHKCVGTSDESTVSENKDGWEMDEMFATLLCYAESEIRGHKISEMVPTDGLYVDIATQTYNFATAPFKYNASLTEVTADMDLKLHLELDTETATLRHNKFTSAFSFMCGHFFRRDEFASHFKNVHLDIQSCMGGWFEQRCPLAYLGCTFSQKRLQPATQRAKVFYNRDLSIFTLTPEVPACLQNNSPNLSEKAHVKYEDSLSNLPFEVLHHIASYLDSFTLSQLALVSRLFRDICATLLQERGMVAFKWRKKSNSLGGARWKPTIVWEFSTLFSKVENWCIGDTPSMAEHLQNCPFYQTELKTEPFTLTNMSDIKGKGGNNLVSLFMGHK", "length": 692, "header": "tr|A0A8N7UTA2-1|A0A8N7UTA2_DANRE Isoform 1 of F-box only protein 40 isoform X1 OS=Danio rerio OX=7955 GN=fbxo40.2 PE=4 SV=2 CANONICAL=A0A8N7UTA2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IB22-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTA2/entry#A0AC58IB22-1", "sequence": { "sequence": "MVINCRLLCGASFHLCKEDEHSLLCPNEKVPCINAHYGCPFTMCRSRLAKHLEVCPASIVCCSMEWNRWPVQNPDAPLYPNLLKELHEQESLDLSMALRDQKHLCARLKMRNCFPELMEEREEEPTPVEEEEDEEAAAGREAVPNGISINEHEGSVLLNGPSKSCEKAMNENVVLNGDIDKEKYNLFEKMFSMEKGGCKQAEASKTEEKKGQKAPSVTKPQDAFIEPKNEETNAPSVDVSKCGLAPWQDGVLERLGQEVKPREFNMYIVHHGRMLISFGQMDACTPRERDFVYGSLEPIPVQTLRSFKVPTSYKQKRIQLREFKARVMTEHKCVGTSDESTVSENKDGWEMDEMFATLLCYAESEIRGHKISEMVPTDGLYVDIATQTYNFATAPFKYNASLTEVTADMDLKLHLELDTETATLRHNKFTSAFSFMCGHFFRRDEFASHFKNVHLDIQSCMGGWFEQRCPLAYLGCTFSQKRLQPATQRAKVFYNRDLSIFTLTPEVPACLQNNSPNLSEKAHVKYEDSLSNLPFEVLHHIASYLDSFTLSQLALVSRLFRDICATLLQERGMVAFKWRKKSNSLGGARWKPTIVWEFSTLFSKVENWCIGDTPSMAEHLQNCPFYQTELKTEPFTLTNMSDIKGKGGNNLVSLFMGHK", "length": 659, "header": "tr|A0AC58IB22-1|A0AC58IB22_DANRE Computationally mapped isoform of F-box only protein 40 isoform X2 OS=Danio rerio OX=7955 GN=fbxo40.2 PE=4 SV=1 CANONICAL=A0A8N7UTA2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 159, "start_aa": "Thr", "end_pos": 159, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr159", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "R-DRE-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-DRE-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LXQ1-1", "protein_name": "F-box protein 40", "gene_name": "Fbxo40", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRARRPPPALHRHCEGCIDRHCRVPAEPSVSCLVISCHLLCGATFHMCKESEHTLLCPLEQVPCLNSEYGCPLSMARHKLAKHLQVCPASVVCCSMEWNRWPNVDSETVLHENIMKESPSEECLDTALALQDQKVLFRSLKMVELFPETRDATEEEPAMNGDTSWEETAGAVGGVDAGLVPNSCLPATNGQTMELSQEERDALAKTKEGMDLDKFGKWESMFSKEHAASVLTGSSGKSEDKNENVSGKEQRSGDGSTGDAECSTERRGPQESPKPQEPPTTIEMTGLAPWQDGVLERLKTAVDAKDYNMYLVHNGRMLIHFGQMPACTPKERDFVYGNLEAQEVKTVYTFKIPVSYCGKRARLGDAMLRCRPSEHKAVDTSDLGISVEDLPKSDLIKTTLQCALERELKGHVISESRSIDGLFMDLATQTYNFESEQFSSETVLADLLGTTQSGGLHVELHSECVTRRHNKSSSAFTFTCNKFFRRDEFPLHFKNVHTDIQSCLNGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQELKTFAIKPEVAPELSEKWKSDHLSGRDGKSLNSLTSLPLEVLQYIAGFLDSISLSQLSQVSVLMRNICATLLQERGMVLLQWKKKRYSHGGTSWKVHNQIWQFSSLFSKIKSWEFNDVTSMSEHLKTCPFNVVEHKTDPIRLTSMCQPQEQARESLVSTFRARPRGRHS", "length": 710 }, "evidence": [ { "id": "RGD:1309781", "url": "https://alliancegenome.org/gene/RGD:1309781#orthology", "database": "AGR" }, { "id": "MGI:2443753", "url": "https://alliancegenome.org/gene/MGI:2443753#orthology", "database": "AGR" }, { "id": "HGNC:29816", "url": "https://alliancegenome.org/gene/HGNC:29816#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-105", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-105#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P62932-1", "protein_name": "F-box only protein 40", "gene_name": "Fbxo40", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRARKPPPALHRHCEGCFNRHCHVPVEPSVSCLVISCHLLCGATFHMCKESEHTLLCPLEQVPCLNSEYGCPLSMARHKLAKHLQVCPASVVCCSMEWIRWPNVDSETFLHENIMKETPSEECLDTALALQDQKVLFRSLKMVELFPETRDATEEEPDMNGDTSWEETGGAVGGVDARLAPNSCLPATSRQMMELSQEERDALAKTKEGMDLDKFGKWESMFSKEHAASVLTGSLGKSEDKNGDVAGKEQCSSNVRIGDAEGSAERRGPQESQKSQELPATMEMTGLAPWQDGVLERLKTAVDAKDYNMYLVHNGRMLIHFGQMPACTPKERDFVYGNLEAQEVKTVYTFKIPVSYCGKRARLGDAMLKCRPSEHKAVDTSDLGISVEDLPKSDLIKTTLQCALERELKGHVISESRSIDGLFMDLATQTYNFEPEQFSSETVLADLLGTAQPGGLHVELHSECVTRRHNKSSSAFTFTCNKFFRRDEFPLHFKNVHTDIQSSLDGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQELKTFAIKPEVAPELSEKWKSDHLSGRDGKSLNSLTSLPLEVLQYIAGFLDSISLSQLSQVSVLMRNICATLLQERGMVLSQWKKKRYSHGGTSWKVHNQIWQFSSLFSKINSWEFNDVTSMSEHLKTCPFNIVERKTDPIRLTSMCQPQEKARESLVSTFRARPRGRHF", "length": 710 }, "evidence": [ { "id": "RGD:1309781", "url": "https://alliancegenome.org/gene/RGD:1309781#orthology", "database": "AGR" }, { "id": "MGI:2443753", "url": "https://alliancegenome.org/gene/MGI:2443753#orthology", "database": "AGR" }, { "id": "HGNC:29816", "url": "https://alliancegenome.org/gene/HGNC:29816#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-105", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-105#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UH90-1", "protein_name": "F-box only protein 40", "gene_name": "FBXO40", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKARRSPPGHHRHCEGCFNRHCHIPVEPNTSCLVISCHLLCGATFHMCKEAEHQLLCPLEQVPCLNSEYGCPLSMSRHKLAKHLQVCPASVVCCSMEWNRWPNVDSETTLHENIMKETPSEECLDTALALQDQKVLFRSLKMVELFPETREATEEEPTMNGETSVEEMGGAVGGVDIGLVPHGLSATNGEMAELSQEEREVLAKTKEGMDLVKFGQWENIFSKEHAASALTNSSASCESKNKNDSEKEQISSGHNMVEGEGAPKKKEPQENQKQQDVRTAMETTGLAPWQDGVLERLKTAVDAKDYNMYLVHNGRMLIHFGQMPACTPKERDFVYGKLEAQEVKTVYTFKVPVSYCGKRARLGDAMLSCKPSEHKAVDTSDLGITVEDLPKSDLIKTTLQCALERELKGHVISESRSIDGLFMDFATQTYNFEPEQFSSGTVLADLTAATPGGLHVELHSECVTRRHNKSSSAFTFTCNKFFRRDEFPLHFKNVHTDIQSCLNGWFQHRCPLAYLGCTFVQNHFRPPGQKAKVIYSQELKTFAIKPEVAPELSEGRKNNHLLGHGGKSQNSLTSLPLEILKYIAGFLDSVSLAQLSQVSVLMRNICATLLQERGMVLLQWKKKRYSHGGTSWRVHREIWQFSSLFSKIKSWEFNEVTSMSEHLKSCPFNIVEHKTDPILLTSMCQPREQARESLVSTFRIRPRGRYVS", "length": 709 }, "evidence": [ { "id": "RGD:1309781", "url": "https://alliancegenome.org/gene/RGD:1309781#orthology", "database": "AGR" }, { "id": "MGI:2443753", "url": "https://alliancegenome.org/gene/MGI:2443753#orthology", "database": "AGR" }, { "id": "HGNC:29816", "url": "https://alliancegenome.org/gene/HGNC:29816#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-105", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-105#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UTA2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTA2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UTA2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTA2" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UTA2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 432, "end_pos": 434, "annotation": "n_glycosylation_sequon" }, { "start_pos": 546, "end_pos": 548, "annotation": "n_glycosylation_sequon" }, { "start_pos": 550, "end_pos": 552, "annotation": "n_glycosylation_sequon" }, { "start_pos": 672, "end_pos": 674, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UTA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTA2" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 560, "end_pos": 614, "start_aa": "Glu", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UTA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTA2" }, { "id": "PS50145", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50145" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRAF-type", "eco_id": "ECO_0000259", "start_pos": 54, "end_pos": 96, "start_aa": "His", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 159 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 432, "end_pos": 434 }, { "start_pos": 546, "end_pos": 548 }, { "start_pos": 550, "end_pos": 552 }, { "start_pos": 672, "end_pos": 674 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UTE4-1", "uniprot_ac": "A0A8N7UTE4", "uniprot_id": "A0A8N7UTE4_DANRE", "mass": { "chemical_mass": 155322.0, "monoisotopic_mass": 155322.0 }, "refseq": { "ac": "XP_073799912", "name": "uncharacterized protein prr36b", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073799912" }, "gene_names": [ { "name": "prr36b", "type": "recommended", "evidence": [ { "id": "A0A8N7UTE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTE4" } ] }, { "name": "prr36b", "type": "synonym", "evidence": [ { "id": "XP_073799912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073799912" } ] } ], "protein_names": [ { "name": "Uncharacterized protein prr36b", "type": "synonym", "evidence": [ { "id": "A0A8N7UTE4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTE4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein prr36b", "type": "synonym", "evidence": [ { "id": "XP_073799912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073799912" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_073799912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073799912" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UTE4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTE4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "prr36b", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTE4", "locus": {} } ], "crossref": [ { "id": "A0A8N7UTE4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UTE4", "database": "AlphaFoldDB", "categories": [] }, { "id": "568650", "url": "https://www.ncbi.nlm.nih.gov/gene/568650", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:568650", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568650", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UTE4", "url": "https://www.orthodb.org/?gene=A0A8N7UTE4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22427", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22427", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22427:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22427:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_073799912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_073799912", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UTE4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTE4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UTE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTE4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MKPDGVDTASMEPMEALNAGPAIEVAPVGEAQDQALPATEAEPQPTAPLSATNKTGKEKPTDPKAKTKAPAKTKTPIAGTKASTTSSRPPTGQSRLTNGAQKSQANGVTKKTTTGSLDKKTSTTAGPKKPVGSATAPTAKTPTKVAEKKPLGTARPASAPSNGMKTTGTAQPIKKAPAAPANGLKPKPKTTAPAPRPATASTTKSSTTDAPKPSVAKTARSVGSVPAARSSPAAPKPATPTTASKTPTSTSRPTTATPKTPSTTAKPSPAKTTAPPSGRTPTPKTTTPVKKDVSKLSSTPAPKKTTSSPLTRPATSKPAKPDTPKSALTAKAESASKKPSTASKAADVKTSKPKESKATPSKEVSASPKTTGTKPSTKTSSPKKTVGSSTPMSLKGGPKASAPADTAAKEAEKKDIVPAVVAATTAVAAVVSVVASEGPEKVPEDLSSVAVSEVKLEDSFTTPIPAYSETKDSVEMATPVIPSTMDKSDKDATPMPYLSEEQIEDRTSDETPEETGPFLPHIHPASEETTKDKTMSVIPPTSFEATEVKDSTAFTLTSEEIPVDTTTSVIPPTSYEERQETVSPVILSTFEETYEHENVSLIPPTSYEERQETVSPVINPTFEETHEHVTTSFVPPTSCDARKETVSPVIPHASEETPEHETTSVIPPTSYEAREESVSPVHASKEIPEEVTTHTSYEAPEQNTIESAFDEEPEDPDTPVISPTPDDVELTYAQDISQSMDTYKDNNASSLFSAEVDQEEPVPAESPLGTTILSPPSSPTGPISMPVEIPSSSPFQDLQCAAETWPQSSSLFPHTATTEDMEQDEESEEDDDKQQEDIAMSSAAKVAMGGFEMLGSAGGDHIRPEAPVSAWQEREEAVEKAEEEINEDNDEEEEEEEDDEEDEVREIGIEEPLPQTEKDDDFKKGVTGFASSDWGMMQSDDMFSSNKHDSEVTSPFSAEDKCSAKETHGFAINETDEEKPFTGPPGIQSFGSEDEEEDEEDLKEHMDLEHDAEDHKQQEEKEKEDEDVEMIHKGMAESGVCGNYDDDDEEDEEENQNYTEERCLDFSSTGHNAPATTMPSTTAWSQSNPFSDSLAQPASFLSESSLSDTRFQDPDTTSTFSAVPETSITFAADPDTPPKSPAPPLIQASEPQPESQAETGYSVPAEPGILAAPAIGMSQSSTLSGTALAAHSSSETSTPEELRDYDSSSGVESRSDKQQTPVPAIQPDMEQDLGIHLERGDGEEEEAETLPADEILGDAATAPASVPSSPSTSGDEASDTEGEMQINDPDVAVDDKTTVPHNLSALDEDEEAPEQIGEEDGGTPQSANSVASYGFDCSASISNAHSMAESCGKSPGIFSLENEEQLPEEAKDPSFIKELTLPAATAYSDDLLGCPVDLLPISEPATERDAGFDEHYMLCSKTDPGTMEEMDPESPMHLSPQHGDDTDGQPPYFSAICDKTDNFLAGNV", "length": 1468, "header": "tr|A0A8N7UTE4-1|A0A8N7UTE4_DANRE Isoform 1 of Uncharacterized protein prr36b OS=Danio rerio OX=7955 GN=prr36b PE=1 SV=2 CANONICAL=A0A8N7UTE4-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UTE4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UTE4/entry#A0A8N7UTE4-1", "sequence": { "sequence": "MKPDGVDTASMEPMEALNAGPAIEVAPVGEAQDQALPATEAEPQPTAPLSATNKTGKEKPTDPKAKTKAPAKTKTPIAGTKASTTSSRPPTGQSRLTNGAQKSQANGVTKKTTTGSLDKKTSTTAGPKKPVGSATAPTAKTPTKVAEKKPLGTARPASAPSNGMKTTGTAQPIKKAPAAPANGLKPKPKTTAPAPRPATASTTKSSTTDAPKPSVAKTARSVGSVPAARSSPAAPKPATPTTASKTPTSTSRPTTATPKTPSTTAKPSPAKTTAPPSGRTPTPKTTTPVKKDVSKLSSTPAPKKTTSSPLTRPATSKPAKPDTPKSALTAKAESASKKPSTASKAADVKTSKPKESKATPSKEVSASPKTTGTKPSTKTSSPKKTVGSSTPMSLKGGPKASAPADTAAKEAEKKDIVPAVVAATTAVAAVVSVVASEGPEKVPEDLSSVAVSEVKLEDSFTTPIPAYSETKDSVEMATPVIPSTMDKSDKDATPMPYLSEEQIEDRTSDETPEETGPFLPHIHPASEETTKDKTMSVIPPTSFEATEVKDSTAFTLTSEEIPVDTTTSVIPPTSYEERQETVSPVILSTFEETYEHENVSLIPPTSYEERQETVSPVINPTFEETHEHVTTSFVPPTSCDARKETVSPVIPHASEETPEHETTSVIPPTSYEAREESVSPVHASKEIPEEVTTHTSYEAPEQNTIESAFDEEPEDPDTPVISPTPDDVELTYAQDISQSMDTYKDNNASSLFSAEVDQEEPVPAESPLGTTILSPPSSPTGPISMPVEIPSSSPFQDLQCAAETWPQSSSLFPHTATTEDMEQDEESEEDDDKQQEDIAMSSAAKVAMGGFEMLGSAGGDHIRPEAPVSAWQEREEAVEKAEEEINEDNDEEEEEEEDDEEDEVREIGIEEPLPQTEKDDDFKKGVTGFASSDWGMMQSDDMFSSNKHDSEVTSPFSAEDKCSAKETHGFAINETDEEKPFTGPPGIQSFGSEDEEEDEEDLKEHMDLEHDAEDHKQQEEKEKEDEDVEMIHKGMAESGVCGNYDDDDEEDEEENQNYTEERCLDFSSTGHNAPATTMPSTTAWSQSNPFSDSLAQPASFLSESSLSDTRFQDPDTTSTFSAVPETSITFAADPDTPPKSPAPPLIQASEPQPESQAETGYSVPAEPGILAAPAIGMSQSSTLSGTALAAHSSSETSTPEELRDYDSSSGVESRSDKQQTPVPAIQPDMEQDLGIHLERGDGEEEEAETLPADEILGDAATAPASVPSSPSTSGDEASDTEGEMQINDPDVAVDDKTTVPHNLSALDEDEEAPEQIGEEDGGTPQSANSVASYGFDCSASISNAHSMAESCGKSPGIFSLENEEQLPEEAKDPSFIKELTLPAATAYSDDLLGCPVDLLPISEPATERDAGFDEHYMLCSKTDPGTMEEMDPESPMHLSPQHGDDTDGQPPYFSAICDKTDNFLAGNV", "length": 1468, "header": "tr|A0A8N7UTE4-1|A0A8N7UTE4_DANRE Isoform 1 of Uncharacterized protein prr36b OS=Danio rerio OX=7955 GN=prr36b PE=1 SV=2 CANONICAL=A0A8N7UTE4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 724, "start_aa": "Thr", "end_pos": 724, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr724", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:568650", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568650", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1057, "end_pos": 1059, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1302, "end_pos": 1304, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 598, "end_pos": 600, "annotation": "n_glycosylation_sequon" }, { "start_pos": 747, "end_pos": 749, "annotation": "n_glycosylation_sequon" }, { "start_pos": 973, "end_pos": 975, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 724 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1057, "end_pos": 1059 }, { "start_pos": 1302, "end_pos": 1304 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 598, "end_pos": 600 }, { "start_pos": 747, "end_pos": 749 }, { "start_pos": 973, "end_pos": 975 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UUR0-1", "uniprot_ac": "A0A8N7UUR0", "uniprot_id": "A0A8N7UUR0_DANRE", "mass": { "chemical_mass": 50060.0, "monoisotopic_mass": 50060.0 }, "refseq": { "ac": "XP_686241", "name": "G-protein coupled receptor 135 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686241" }, "gene_names": [ { "name": "gpr135", "type": "recommended", "evidence": [ { "id": "A0A8N7UUR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUR0" } ] }, { "name": "gpr135", "type": "synonym", "evidence": [ { "id": "XP_686241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686241" } ] } ], "protein_names": [ { "name": "G-protein coupled receptor 135 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_686241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686241" }, { "id": "A0A8N7UUR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUR0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_686241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686241" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUR0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUR0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gpr135", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUR0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060420-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060420-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUR0", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UUR0", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd15212", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15212", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "557986", "url": "https://www.ncbi.nlm.nih.gov/gene/557986", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUR0", "url": "https://www.orthodb.org/?gene=A0A8N7UUR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22752", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22752", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22752:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22752:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_686241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686241", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UUR0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQS5", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQS5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060420-3", "url": "https://zfin.org/ZDB-GENE-060420-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDLPSIISNTTADNMSGSGYILEIVTTKPGVNTLSTQASNYTDVHRDIPVRSSEGNSVLQGIAVAAQALLLLAIFLLSSLGNSAVVVVIIKHRQLRTVTNAFIMSLSLSDFLTAVLCLPFSFMMLFSKDGKWMFGEPFCIANGFFNTCFGIISTLTMTLISFDRYYAIVRQPQAKIGRRRAIQLLVAVWFSAVVFSFPWYLFMETSRRLVVHKQGFYHCMYVFHSGTSRMGTAYSISLIVICYLLPFALMCFCHYNICKTVRLSEIRVRPVTTYAHLLRFYSEMRTATTVLIMIVFSIFCWGPYCLMGIITALGNYSFTPAMDTVAIWMAWANGAINPLIYAIRNPNISMLLGRSREEGYRTRNIAAYLSTQTQRRDAVRSRADRIRDRYVSRHGANSRLSSSSPANGGDVAMWACKNPAVFFCRDAHPDTITEPPVPKVETADTSL", "length": 447, "header": "tr|A0A8N7UUR0-1|A0A8N7UUR0_DANRE Isoform 1 of G-protein coupled receptor 135 isoform X1 OS=Danio rerio OX=7955 GN=gpr135 PE=3 SV=1 CANONICAL=A0A8N7UUR0-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UUR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUR0/entry#A0A8N7UUR0-1", "sequence": { "sequence": "MDLPSIISNTTADNMSGSGYILEIVTTKPGVNTLSTQASNYTDVHRDIPVRSSEGNSVLQGIAVAAQALLLLAIFLLSSLGNSAVVVVIIKHRQLRTVTNAFIMSLSLSDFLTAVLCLPFSFMMLFSKDGKWMFGEPFCIANGFFNTCFGIISTLTMTLISFDRYYAIVRQPQAKIGRRRAIQLLVAVWFSAVVFSFPWYLFMETSRRLVVHKQGFYHCMYVFHSGTSRMGTAYSISLIVICYLLPFALMCFCHYNICKTVRLSEIRVRPVTTYAHLLRFYSEMRTATTVLIMIVFSIFCWGPYCLMGIITALGNYSFTPAMDTVAIWMAWANGAINPLIYAIRNPNISMLLGRSREEGYRTRNIAAYLSTQTQRRDAVRSRADRIRDRYVSRHGANSRLSSSSPANGGDVAMWACKNPAVFFCRDAHPDTITEPPVPKVETADTSL", "length": 447, "header": "tr|A0A8N7UUR0-1|A0A8N7UUR0_DANRE Isoform 1 of G-protein coupled receptor 135 isoform X1 OS=Danio rerio OX=7955 GN=gpr135 PE=3 SV=1 CANONICAL=A0A8N7UUR0-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUR0/entry#A0AC58HQS5-1", "sequence": { "sequence": "METSRRLVVHKQGFYHCMYVFHSGTSRMGTAYSISLIVICYLLPFALMCFCHYNICKTVRLSEIRVRPVTTYAHLLRFYSEMRTATTVLIMIVFSIFCWGPYCLMGIITALGNYSFTPAMDTVAIWMAWANGAINPLIYAIRNPNISMLLGRSREEGYRTRNIAAYLSTQTQRRDAVRSRADRIRDRYVSRHGANSRLSSSSPANGGDVAMWACKNPAVFFCRDAHPDTITEPPVPKVETADTSL", "length": 245, "header": "tr|A0AC58HQS5-1|A0AC58HQS5_DANRE Computationally mapped isoform of G-protein coupled receptor 135 isoform X2 OS=Danio rerio OX=7955 GN=gpr135 PE=4 SV=1 CANONICAL=A0A8N7UUR0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUR0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUR0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUR0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUR0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUR0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 315, "end_pos": 317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 9, "end_pos": 11, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UUR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUR0" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 81, "end_pos": 341, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 315, "end_pos": 317 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 9, "end_pos": 11 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UUS4-1", "uniprot_ac": "A0A8N7UUS4", "uniprot_id": "A0A8N7UUS4_DANRE", "mass": { "chemical_mass": 117303.0, "monoisotopic_mass": 117303.0 }, "refseq": { "ac": "XP_687189", "name": "uncharacterized protein si:dkey-229b18.3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687189" }, "gene_names": [ { "name": "si:dkey-229b18.3", "type": "recommended", "evidence": [ { "id": "A0A8N7UUS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUS4" } ] }, { "name": "si:dkey-229b18.3", "type": "synonym", "evidence": [ { "id": "XP_687189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687189" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkey-229b18.3", "type": "synonym", "evidence": [ { "id": "A0A8N7UUS4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUS4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkey-229b18.3", "type": "synonym", "evidence": [ { "id": "XP_687189", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687189" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_687189.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_687189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687189" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUS4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUS4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-229b18.3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUS4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-6870", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6870", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUS4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UUS4", "database": "AlphaFoldDB", "categories": [] }, { "id": "558830", "url": "https://www.ncbi.nlm.nih.gov/gene/558830", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051481", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051481", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558830", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558830", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UUS4", "url": "https://www.orthodb.org/?gene=A0A8N7UUS4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24410", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24410", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24410:SF40", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24410:SF40", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_687189", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687189", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UUS4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-6870", "url": "https://zfin.org/ZDB-GENE-030131-6870", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASECTYDSDDTFRTTKHSADEQRARAGFVNGDCASVSTSALFEVIDGSLFRKKLEKGFVQYREVLAEDKRLQSIVTFHEKRPGKSHHTLEDTYRLVAEHYWWEGMYFQVRDYVLGCEECQLSQSERSVCSDVSLISRMVESHSHEVLSKLNSQREAGLFCDITLKTGGGQSFVAHKAVLAAVSEYFQELFTEMDSATDPQSHVDLTGFSEQSLLALLEFCYTSTLNLNLDILTEVCTMARHLRMWPALEACSAIKRERETCQLHPLLSIPGEPNNSVAGPIRKEHSLTSGGKVGHKRRRPNEEGEGSGSSCCIQAQYREHTVDRLTDESETETSNPQFQCQPLSSFQVEENCFPCSPNRRMKLMDFKSPSCKKKTSTRPTSSVISTSPCTSTRSSSPSRRLLRSSPGAALALRRLLPKIDLSTKRKKKTSSYRVYKPQYEISATSSKSQAKSFTRVTSLNVKQEDVEEDVCKQVPQDEVHSPRAQEKYRLLSFLGLRRKSLVPGPEELSGWGQKKRLRKLKISDYSLTARRKPRAQDVPLSFGTSLGVLAAVNPTLSLCDMSRMDLLNRPVKVELQESWNQQRSKRKRHDPVQTITRTTRSRSLLQTDSSAIDCPIRRLHKNQDKAPSSPARRGRGPAHNPSSPSKSTMLRIKRDSSGSAILQPIHRRNTVCSSQGTPSKGVGRRGRPPADRTVRVATTMSRHKPGPTGKPKSSKQVESKTKCSRVSGIPQGRHSRTERGTQVKENRKVMKCATRKKTPEVQYNVMNWDGSNHQHLHSHPLYKTIKEEPADPLPLAQPFPTNDPSDLGKRQSKPPVKLLDQGFLFGLCRPPSGIKREEESVDIYLTRSVSHGSSSNCDLSPGKKDRLRARLMPDRTGLNGPHWAGLGNRQSPFSQRIGIQVKTERNETNTSHVSRSSRHPQVSKRSCKVTKEPTKTKNVNKLLPLSSRRSVLLESIRQSRLKQQKGPQDKSSKGPHACLQCRASYRDCDALIMHQIKHIEGKHWPCPLCSKTFFRQRNVRNHIRTHNTKLYKCRQCIAAQ", "length": 1041, "header": "tr|A0A8N7UUS4-1|A0A8N7UUS4_DANRE Isoform 1 of Uncharacterized protein si:dkey-229b18.3 OS=Danio rerio OX=7955 GN=si:dkey-229b18.3 PE=4 SV=1 CANONICAL=A0A8N7UUS4-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UUS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUS4/entry#A0A8N7UUS4-1", "sequence": { "sequence": "MASECTYDSDDTFRTTKHSADEQRARAGFVNGDCASVSTSALFEVIDGSLFRKKLEKGFVQYREVLAEDKRLQSIVTFHEKRPGKSHHTLEDTYRLVAEHYWWEGMYFQVRDYVLGCEECQLSQSERSVCSDVSLISRMVESHSHEVLSKLNSQREAGLFCDITLKTGGGQSFVAHKAVLAAVSEYFQELFTEMDSATDPQSHVDLTGFSEQSLLALLEFCYTSTLNLNLDILTEVCTMARHLRMWPALEACSAIKRERETCQLHPLLSIPGEPNNSVAGPIRKEHSLTSGGKVGHKRRRPNEEGEGSGSSCCIQAQYREHTVDRLTDESETETSNPQFQCQPLSSFQVEENCFPCSPNRRMKLMDFKSPSCKKKTSTRPTSSVISTSPCTSTRSSSPSRRLLRSSPGAALALRRLLPKIDLSTKRKKKTSSYRVYKPQYEISATSSKSQAKSFTRVTSLNVKQEDVEEDVCKQVPQDEVHSPRAQEKYRLLSFLGLRRKSLVPGPEELSGWGQKKRLRKLKISDYSLTARRKPRAQDVPLSFGTSLGVLAAVNPTLSLCDMSRMDLLNRPVKVELQESWNQQRSKRKRHDPVQTITRTTRSRSLLQTDSSAIDCPIRRLHKNQDKAPSSPARRGRGPAHNPSSPSKSTMLRIKRDSSGSAILQPIHRRNTVCSSQGTPSKGVGRRGRPPADRTVRVATTMSRHKPGPTGKPKSSKQVESKTKCSRVSGIPQGRHSRTERGTQVKENRKVMKCATRKKTPEVQYNVMNWDGSNHQHLHSHPLYKTIKEEPADPLPLAQPFPTNDPSDLGKRQSKPPVKLLDQGFLFGLCRPPSGIKREEESVDIYLTRSVSHGSSSNCDLSPGKKDRLRARLMPDRTGLNGPHWAGLGNRQSPFSQRIGIQVKTERNETNTSHVSRSSRHPQVSKRSCKVTKEPTKTKNVNKLLPLSSRRSVLLESIRQSRLKQQKGPQDKSSKGPHACLQCRASYRDCDALIMHQIKHIEGKHWPCPLCSKTFFRQRNVRNHIRTHNTKLYKCRQCIAAQ", "length": 1041, "header": "tr|A0A8N7UUS4-1|A0A8N7UUS4_DANRE Isoform 1 of Uncharacterized protein si:dkey-229b18.3 OS=Danio rerio OX=7955 GN=si:dkey-229b18.3 PE=4 SV=1 CANONICAL=A0A8N7UUS4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 678, "start_aa": "Thr", "end_pos": 678, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr678", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:558830", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558830", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUS4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUS4" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUS4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUS4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ubiquitin-dependent protein catabolic process", "id": "GO:0006511", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006511", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUS4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUS4" } ], "pmid": "" }, { "name": "positive regulation of fatty acid 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Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_688398.2. 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Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_684062.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_684062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684062" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUY1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "olfcq11", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUY1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UUY1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06364", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06364", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "556218", "url": "https://www.ncbi.nlm.nih.gov/gene/556218", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556218", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556218", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UUY1", "url": "https://www.orthodb.org/?gene=A0A8N7UUY1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061:SF418", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061:SF418", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_684062", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684062", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UUY1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-641", "url": "https://zfin.org/ZDB-GENE-060503-641", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MWVILHIYFFISCNYMSVALMASSGTCQLQGHFTLNGMYQNGDFLIGGLFEIQYLKAFPGLSFRTEPKLPHCENFYMTSFQQAITMVFAINEINNNPNLLPNITLGYQMYDNCLRLGVAFRAATALISGTEETLSDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMIQILRHFEWTWVGLLYSDDDYGINAALSFHHDVQQFGGCVAFSEILPNDNNQMAVQHIVRVIQNSTAKVVVVFSTSSYLLPVIDEMLLKNITGRQWIASEAWSTSPVLLNPRLRYVLGGTLGIAIRRGEIEGLDNFLLRLRPDNFSQNSMMRIFWENMFECNFDTIGGLRTKLCSGQEDLRSKFTPYTDVSELRASYNVYKAVYALAHALHDLMHCEEGRGPFSENRCVDISNLKPWQLVHYLQRVKFTTGFGDHVSFDKNGDALAIYDVLNWQLSSEESVTVRRIGVVDEGVTTGKVFTLDENAIYWNFETNKPPRSVCSESCPPGTRQATRKGLPVCCFDCLPCGDGEISNTTDTTECIACPNDFWSNPEKDQCIPKEVEFLSYEDPLGISLTTAAMLGTFICALVMTIFAHYRNTPVVRSNNSELSFLLLLSLKLSFLCVLLFIGQPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKNAMKWFGAAQQRGTVLILTALQVLICAVWLSTASPTPHKNSRYIRSIIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDSFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIIILHPERNTKKAIMGKGTKNK", "length": 863, "header": "tr|A0A8N7UUY1-1|A0A8N7UUY1_DANRE Isoform 1 of Extracellular calcium-sensing receptor-like OS=Danio rerio OX=7955 GN=olfcq11 PE=3 SV=1 CANONICAL=A0A8N7UUY1-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UUY1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY1/entry#A0A8N7UUY1-1", "sequence": { "sequence": "MWVILHIYFFISCNYMSVALMASSGTCQLQGHFTLNGMYQNGDFLIGGLFEIQYLKAFPGLSFRTEPKLPHCENFYMTSFQQAITMVFAINEINNNPNLLPNITLGYQMYDNCLRLGVAFRAATALISGTEETLSDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMIQILRHFEWTWVGLLYSDDDYGINAALSFHHDVQQFGGCVAFSEILPNDNNQMAVQHIVRVIQNSTAKVVVVFSTSSYLLPVIDEMLLKNITGRQWIASEAWSTSPVLLNPRLRYVLGGTLGIAIRRGEIEGLDNFLLRLRPDNFSQNSMMRIFWENMFECNFDTIGGLRTKLCSGQEDLRSKFTPYTDVSELRASYNVYKAVYALAHALHDLMHCEEGRGPFSENRCVDISNLKPWQLVHYLQRVKFTTGFGDHVSFDKNGDALAIYDVLNWQLSSEESVTVRRIGVVDEGVTTGKVFTLDENAIYWNFETNKPPRSVCSESCPPGTRQATRKGLPVCCFDCLPCGDGEISNTTDTTECIACPNDFWSNPEKDQCIPKEVEFLSYEDPLGISLTTAAMLGTFICALVMTIFAHYRNTPVVRSNNSELSFLLLLSLKLSFLCVLLFIGQPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKNAMKWFGAAQQRGTVLILTALQVLICAVWLSTASPTPHKNSRYIRSIIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDSFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIIILHPERNTKKAIMGKGTKNK", "length": 863, "header": "tr|A0A8N7UUY1-1|A0A8N7UUY1_DANRE Isoform 1 of Extracellular calcium-sensing receptor-like OS=Danio rerio OX=7955 GN=olfcq11 PE=3 SV=1 CANONICAL=A0A8N7UUY1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:556218", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556218", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KAL5-1", "protein_name": "Vomeronasal 2 receptor 19 like 1", "gene_name": "Vom2r19l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTMIFLFLLLNIPLLMVDFIHPRCFWRMKQNEDKDGNPGTGCTFFLQSVHWPVEKEYYSDIFNIQMHNENHKYALALAFAIYEINGNPDLLPNMSLIFEFTRDVCDWESQLNSVIQSSLKNHNILPNYICKEFTKCPMALTGLNWTTTLKLHTILNNFISQQFLQVTYGPFHPVLSDNEKFPYLYQMASDDKSLALALVSFIIHFGWNWVGLAISNNDQGIQFLSYLRREMEKGTVCFAFVNMIPVNMHLYMSRAEMYYNQIMTSSTNVVILYGDTDSTLAVSFRMWESLGIEKIWVTNSWWAATLSKKDHTFDNLYGTYAFGQHHGEISGFKNFVQTLNPAKYSDEHLVKLEWMYFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFTGGSYDIYNAVYSFAHALHEMTFQIFDNLPKDNGREHNYSCKKLCSFLRKTSFTNPVGDRVNMNQRHKQKEEYDIFYIWNFPQGLGIKVKIGMFSPYFPNGQQLHLSEDVLEWAKGSAQMPTSACSADCGPGFRKSWKDGMATCCFHCKPCPENEISNETNVDVCARCPDDQYANIEQNRCIPKAVVFLSYEEPLGMALSLISLGFSVFTIVLLGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSAICILQQITFGVVFTVSVSTVLAKTITVILAFKVTASQRMMKYFLVSRVPNYIIPTFTLFQVILCAVWLGASPPSIDIDAKSEHGHIIIACHKGSVTTFYCVLGYLGTLASGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKIMVAVEIFSTLASSAGMLGCIFVPKCYTVLFRQDQNSLVMIRMKSSSHAHIS", "length": 857 }, "evidence": [ { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0R4IS27-1", "protein_name": "Olfactory receptor CG6 precursor", "gene_name": "olfcg6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFLFYTILLFHLLHTKVENSLCRIMGDSNYPLFSKNGDVSIGGIFAIHRKETLPSFEFMQKPQPLSCSSVNLRDFRLAQTMIFAVEEINRSKSLLPNVSIGYKIYDTCGSRLSTMTAIMGLMNGQDFSTEDRCNGQSRLHAIIGESESSATIVLSRTTGPFRIPVISHSSSCECLSNKKDYPSFFRTISSDYHMSRALVYIVKHLDWSWVGAVNSDNDYGNNGMAIFLKAAHEEGICVEYSVKFYRTEPEKLKKVVDTINKGTAKVIVAFVSFVEMGLLIDQLSIQNITGIQMIGVEPWITANTYITSNSFRAMGGSLGFATKYIYIEGFAEYVMTPFWNTAFPCSESDRNHSHYELICSRYEDLLALKNDNKDVNEHRYSSNVYKAVYAVAHSLHGLLNCKEQEGCEKGLTIQPQQVVKALKNINFTIKSGDSVWFDNTGSVVALYEVVNWQKDSDGSFQFKSVGFYDAMMPPYKNLRLNTKNIVWAGGQLEKPRSVCSESCAPGTRKAAQKGRPVCCYDCIPCAEGEISNETDSINCKQCPGEYWSNTERNRCVIKAVEFLSFSEVMGIVLVIFSLFGAGLTVLVAVLFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTKWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPVQQRLSVFAFTLIQVLICVLWLTISPPFPYKNMKYYKEKIILECNLGNTIGFWAVLGYIGLLAALCFLLAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSFGLLVSIFAPKCFIILLKPEQNTKQHVMGKTTCSL", "length": 837 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A3B2W422-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r54", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSASMWGYRVTQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQKEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSYQSLGKIEETVQKMQKCTAKVVLVFLSNLNFQLILRGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVSSLNAEETVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFVLALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQICLSPGTSTFVVLIASLIQVVLCGVWLATSPPFPDKDMISEPQHIVIQCQEGSGATFFCVLGYLGFLAGGTFSVAFLARGLPDIFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLKQGYCAQQEKQGEMLQRRYKFSGESPEPNI", "length": 878 }, "evidence": [ { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W4A7-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r53", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCTLLSVLFGCLSGSALSGPRVWIIPRQSPRFDRPGDVIVGGSFSIFHFSDGTLSNFTAPPPVLKTSSASMWSYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTCSHAVTQLVIHFQWSWVIILAHDDDFGQQASSLATQMLTPAGVCIEYHLHVPSHQSFGKIEETVQKMQKCTARVVLVFLSNSNFQLILHGLLAVPVSGQVWVSMDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSRIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHNLRNVYFKTSDGNKIMFDANGDLVTQFDIFQGKKTPAGVFHLVHVGLIDPQASSGNKMMVQLKQDLQVSSLNAEITVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTIFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQVCLSSGASTSVVLIASLIQVVLCGIWLITSPPFPDRDMISEPRHTVIQCHEGSGANFFCVLGFLGFLAGGTFSVAFLARGLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHQVQHNRQCEMLQRRCVSSGESLGSSL", "length": 878 }, "evidence": [ { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W842-1", "protein_name": "Vomeronasal 2, receptor 66", "gene_name": "Vmn2r66", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLISVFWFLKISSIFCHLSDPRCFWRIKDTKNHLGDKENNCFFSIYTKRGYVKNDYFSCNLDKQVTPKTIHLIFSVYLAIEEINKDYHILPNISLLVNIECDQRIYDKKSGLGLKSKEIIPNYYCRNQRRYLIVLTIPEWTVSTSLGPFLYISRIPELYCGNFHLLLNDNEQFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGAIVTNDDHGIQFLSELRGEMQKHIVCLSVAIIIQTEKIMALKEFHTHYNQIIMSSAKVVIVYGDKDSPIHFALIVWKSKGIWRIWVSVSQFDMITIIGDFLLYSSIGTFIFSHQQPEIPGFEQFIQTVHPSNYSSEHSLAKLWWTYFRCSLPPSNCKKLKNCPTTTVFKWLFMTPLGMAMSNTCYNLYNGVYAVALSLHEMILQQVDTWSMNAGKELEFDSWKLFYFLKTLQFVNPAGELVIMNQNLKQDTEYDIFFIMDFKKYYGLKIKIGRFSGHLPSGQQLLMSTEMIKWATGIDQILPSVCSMPCRPGLRKSPQEGKDICCFVCYPCPENEISNMTSNVIIYQNMDQCVKCPEDQYANEDQTLCLQKVVAVLDYRDPLGKALAGFALCFSVLTSVVICVFLKHRETPIVKANNQTLSYVLLISLIFCFMSSLLYIGHPTMVICILQQTTFAIVFTVAASTILAKTITVVLAFKATVPGRRMRWLLVSGAPKYIILICTMVQLILCGIWLRISPPFVDADIHMLHGQIIIVCNKGSVVAFYCVLGYMGSIALASFTVAFLARNLPHTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTTVAVEVFCILASSAGLLLCIFAPKCYLILLRPQTNSFYKFRRPHAKAENIS", "length": 858 }, "evidence": [ { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2WBA1-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r56", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLSCHWLSDPLAGMWLCTLLPVLFGCPSGSALSGARAWLLPRQSPHFDRPGDVIVGGSFSIFRFSNGTLSNFTAPPAGLQTSSVSMWGYRVAQSFVFAIEEINRSTHLLPNLTLGFSIRNSGDSAHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTSSHAVTQLIIHFQWSWVIILAHDDDFGQQASSLASQVLTPAGVCIEFYLYVPSHQSLGKIEETVRKMQKCTARVVLVFLSNYNFQLILYGLLAVPVSGQVWVSKDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCMWPYQNITVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHDMISYEHQDGKGTNSQDFQPWQLLHVLRKVHFKTPDGSEIMFDANGDLVTKFDIFQGQKTPDGVFHLVCVGLIDPQASSGNKMMVQKKMLKYQMKHAQVPTSVCSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCCIILLKPEKNTSSWLRQGHHV", "length": 865 }, "evidence": [ { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I6GK53-1", "protein_name": "Vomeronasal 2 receptor, 33", "gene_name": "Vom2r33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLCTFLFVLLGCLPGSALSEPRSWILPRQSPHFDRPGDVMVGGSFSIFCFSDGTLSNFTAPPTGLQASRVSMWGYRVAQSFVFAIEEINKSTQLLPNLTLGFSIQNSGDSVHGALYETMGFLTGQEEPIPNYTCCHGSPQAALVGDTRSSLSLPMARLLGLYKFSQISYSSSLPSLSDKIQFPSFLRTLPSDLTSCHAVTQLIIRFQWSWLIILSQDDDFGEQASSLATQQLSAAGVCIEFHLDVPSQHSLGKIEETVQKMQKCTARVVLVFLSNSNFQLILSGLLAASVSGQVWVSNDTLHIAMALSIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLHPSQIPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQVCSGNESLKNKPYPFPEVSKIDAAYTAVYSIAHALHDMVACEHQDGIDTNPQDFHPWQLLHVLKKVHFRTPDGSEIMFDANGDLVTKFDILQGQKTLNGVFHLVHVGMIDPQASSGNIMMIQLKEDLQVSSMNAEITVPTSICSERCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALMAILLAGLALLVLGVFLKHRDTPVVRVNNRTLSYFLLISLSLCSLCSLLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTVTVVLAFRVTKSGSRIQVCLSPGASTSVVLIASLIQVVLCGVWLATSPPFPERDMISEPQHIVIQCQEGSGATFFCVLGFLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHCAHQDRQCSLFH", "length": 864 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N5X2-1", "protein_name": "Olfactory receptor CW1 precursor", "gene_name": "olfcw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTPVLRAIHLVFFLFYPIQSNSEANCKLWKELDLTVVHKEGDVILAGMFPIHSKGIDQELNFRNQPDQRKCWGFNMRVFRWSQAMIFFIEEINRNPTLLPNITLGYRLYDTCGLIALSLRTALSVVSQPMKRSSSEMCSSPSIPIIIGDSGSTLSMAISRLLNLFHIPLVSYFASCACLSNKHQFPYFFRTIPSDVNQANALARLVKHFGWTWVGTVGADDAYGRTGIDLFTAAVTQLGVCVSYRIIIPKLPTQQQLQDIVRTIRDSSAHVLVAFAIEEDIKPVVDEIVLQNVTGKQWVASEAWVTSTLISTKENFPSLSGTIGFAIRRAEIPGLKHFLDSIQPLADPYNVFAREFWETQFQCTLNTSLPTSSTMDPVNYSHSCTGMERMQDTQSIFNDVSQLRVTYNMYKAVYTVAHALHNLLLCQREHRSALTQQCPDIHNLQPWQVIEVLRKVNYTNMFGDLIYFDENGDPVGSYDIVNWQKGGDDVPVQYITVGRFDSSLPKGQQLVLNQNKIVWHGGTNKVPVSVCSASCPPGYRKVRLEGQPVCCYDCMLCAEGSISNTTDQAECLLCPEDFWSNKHRNYCVPKEIEFLSYLEAFGMVLAAIAILGAVAAISVGVVFFRHRDTPLVRANNSELSFLLLISLTLCFICALTFLGQPSHWACPLRRISFGLTFALCLSCLLSKTLVVLIAFKSTLPGNNTARWFRPPQQRLGVFICSLLQGGVCIAWLTTASPYPVKNTWLYRDRIILECHLGSVVYFCCVLGYIGCLAAFCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSYGVLLCIFAPKCYIIIFMPEKNSKKYLMTQK", "length": 866 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PS22-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcx1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQIYATLLTLCLLLYIRVQCQSNNKYKCIYQGDDDTYSFYQGGDLVLGGIFPLHSSTIPQFFSFTTKPKLIQYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPEKGSGQSCEDTRKQPSPVIVGEASSGVSMAVLRTLGTFQIPLVSYFASCSCLSNKREFPAFMRTMPSDLFQIKALVKLVYYFKWTWLGVIGVDTDYARFAIQLFLKESEKYNICPAYVHIYPVALTQNTVEELVKILKSSSARVILNFSVDSYLYGVLKECRRQNVTNLQWIASEAWATSKVLWDDFGDLLKGTLGFAIRRADIPHLGSYLRSVSSSVAQTSPFFTEFWEETFHCRLNGSLNTHVHEEASYNWPACNGNETLDDVYTLYSDVSQLRVSYNVYKAVYLIAHALHDMSTCDPGKGPFKNGTCGSLYQILPWQLLYYMKRTNFTTLGEEVRFDKNGDPIASYDLMNWQRESDGSLQLVRVGIYDASFKDDKDLVIDESVIMWHRGDKAPESLCSKSCLPGSRKARQKGKPVCCFDCISCAEGEISNQTDSIDCLTCSKDTWPNQSQDQCIPKTLEFLSFQEPLGIILWVFSALGACAALAVLCVFVMYRTTPVIRGNNIELSFLLLLFLCACFLIGLTFLGKPTDWLCQIRYPAFGISFTLCISCILAKTVVVLMAFRATIPGNNVMKWFGPVKQRSSVILCTCVQALICIIWLTTKPPLASYNSKFLSATIIVECSVGSEVGFWCVLGYIGFLSSLCFFLAFLARKLPDNFNEAKFITFSMLIFFAVWITFIPVYVSSSGKYMVAVHVFAILASAFGLLMCIFAPKCYVVLLKPERNDKKSMMKK", "length": 866 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PU52-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWISLNIFLYLSLNCIFAASVVNPGTCQLQGHFKLNGMYQDGDFILGGLFEVHFFTLFPKLSFKSEPEPPYCEKFDMESFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCVMLGMAFRAAISLASGTEEYFSNLNCTGPPPVIGVVGDPGSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVRILSHFGWTWVGLIYSDDDYGIYASVSFQQEMQQFGSCISFSEILPHDNNPKDIQRIMEVIKASTASVVVVFSTSSYLMPLIDEVVLQNLTGRQWIASEAWATSPVFHTPRYLPFLGGTLGIAIRRGEILGLQEFLLHIHASNNPKDNMLKIFWENMFRCSFETRSKDTIGEQEKSICTGHEDLSTTKTPYTDVSGLRASYNVYKAVYALAHALHDLMECEEGRGPFDGNSCGNITNLKPWQLVHYLQKVNFKTGFGDHVSFDENGDALAIYDVLNWHPSSDGSIRLHTVGVVNEGAGTGKVLSLDESALYWNFQTKNPPRSVCSASCPPGTRQAMRKGLPICCFDCLPCGDGEISNATDSTECVTCPDEFWSNFDKNQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHLNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGTMKWFGAAQQRCTVLVLTALQVVICAVWLSNASPTPIKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKKAIIRRETKKR", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q146-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYQDGDFILGGLFEVHFFTVFPDLTFTTNPKSPYCEIFNMEGFQHAQTMAFAIEEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLTSGTEESFLNLNCSGPSPVIGIVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSNRKKYPSFFRTIPSDAFQVRAIVQVLKHFKWTWVGLLYSDDDYGVYAAQSFQQEMRQFGLCAAFSEFLPHDNNPRTIQHIMGVIQGSTAKAVVVFAPSSFLIPLMNEVVLQNMTGRQWIASEAWATSLESHIPSFQPFLRGTIGIAIRRGEIQRLHDFLLRIRPSNDPKNYMLRIFWENMFGCSFGKGDTEGEQVIKVCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHALHDLMECEEGKGPFSKNSCADKTNLKPWQVVHYLQNVNFTTGFGDYVSFDKNGDALAIYDVLNWQPSSDESIRIYTVGVVKEGTETGMVLTLDEDAIFWNFETRKPPRSVCSESCPPGTRRATRKGLPVCCFDCLPCGDGEISNTTNAVECFLCPDEFWSNQYNNHCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVIFVFALHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHVVFGISFVLCMSSILVKTMVVIAVFKSSRPEGKGAIKWFGAVQQRSTVVVLTVLQVLICAVWLSTASPTPYKNNQYIRSKIVYECAIGSVVGFSMLLSYIGFLAAASFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFVPAYVSSPGKYTVAVEIFAILASTFGLLIAIFAPKCYIILLHPERNTKNVIMGRETQNK", "length": 829 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q166-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWSPLIICLYLSYNFKSAASILMGSCQLQGHFGLNGMYQAGDVILGGLFEVHLLAVFPELSFRSAPEPPYCEQFDMASFQQAQTMVFAIDEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLVSGTEELFSNLNCTGSPPVIGIVGDSNSTPSIAISSVLGLFRVPIVSYFATCSCLSNRKQYPSFFRTIPSDAFQVRAMVNILKHFGWTWVGLIYSDDDYGNYAAQSFLQDIQIYGGCVAFTEILPLNNNRKYIEHVVGVIQASTARVVVVFSTSTYVLPLMDEVVLQNVTNRQWIASEAWATSPMFHTQRLLPFLGGTLGIAIRRGEIQGLHEFLLHLRPKNDQHNNMVRIFWEKMFGCRFNPGGKGDKQCSGQEDLSSIDTAYTDVKELRASYNVYKTVYALAHALHDLTECDEERGPFSENRCADITNLQPWQLVHYLQKVNFTTGFGDHVSFDKNGDVLAIYDVMNWHPSSDGSISVRTVGVVNEGAASGKVLTLDEDAIYWNFKIKKAPQSVCSESCPPGTRQATKKGLPVCCFDCLPCGDGEISNVTNAIECTVCPDEFWSNKDKDQCVPKEVEFLSYEDPLGISLTTACLLGTCFCALVMIIFCQHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGSMKWFGTTQQRCTVLILTALQVVICIVWLSNSSPAPHKNSQHISSKIVYECAIGSLAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVTSPGKYAVAVEIFAILASSFGLLGAIFAPKCYIILLHPEKNTKKAIMGRQITK", "length": 860 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q1C5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNAHLLFTVKMLCIARLCIAVCGVDLGTCILQGDAQPPALSEDGDFIVGGAFTIHYYVRTEKYTYTRRPQPLECSGSMDFRELRFARALQFAIQEINNSSDLLPGIFLGYHIYDSCGSVPMAIKVALQLANGLDPKYNDTDSCAKSAAVLALVGDSASTPAISISRIFGPFEIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEKEGICVEYSEAYYRTYPLSKLKRVADVIRRSTARVIVAFVAAGDMRFLLEELSKEPLPPMQWIGSEAWVSDPQMLRFNLSIGTMGVAVPRSLIPGFRKFLLDLSPYKVLKFPLLTEFWESSFSCSLQQQTDPSTGMPACDGTEDLGRLKNPYTDTSQLRVSNMVYKATYAIAHALHGIVCNETQCSKNIKVKPRQVFDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPEGQEFSLNKAIIWYDGSEKVPVSVCSENCPPGTRKAVKKGRPVCCYDCIPCGEGEISNKTDSPDCDKCPPDYWPSTEKDKCLPKPVEFLSWDEILGIILAVLSVSGSLLALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWVVLGYIGLLASLCFVLAFLARKLPDNFNEAKFITFSMLIFSAVWITFIPAYVSSPGKFTVAVEIFAILASSFSLILCIFAPKFFIILFRPEENTKKHLMGKVQSKSY", "length": 856 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RHU5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCCYICVTLIASTGTCQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMTSFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTSRQWIASEAWVTAAVFRTPYFQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTTNTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEGSIKLHNIGVVNEVATGMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTSRAMRKGFPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDRCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AUZ8-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcv3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHSLETMTILLLWLLVYHLSVLNPAQASKCLLQNEFEPGLMANGDFVIGGIFPLHYNQEMPDLNFTYKPGPVKCNGFDTRAFRWAITMKLAVEEINKRVDLLPNYTLGYKIFDSCAYPLTGQRSAVAVLNGPNELESPLCADAAPLLAVIGESGSAQSIVVSRILQPFGIPMISYFSSCACLSDRREFPTFFRVIPSDAYQVKAIAKLLRHFNWTWIGVIRGDHEYGRFALQGLLKELEGTGICVAYQKMIPLLYDRQKALEIIHVMSHSTARVVVVFSAEGELTPFLRDYMEQNVTGIQWIASEAWVTSSVFAGSEFDPFLGGTIGFGIRQGQIPRLKEYLTTVNPERYPTNPLVYELWGALYGCSPSWSNLSSHLPSCTGKETVRLQYSAYLNTSSPRISYNVYKAAYAIAYSLHNLIYCTPGKGPFSNSTCANAPHIYPWQLQQYLQEVSFTISGEKVNFDMKGDSIPSYDLINWQRGSAGNIEFINVGMFDGALESGQELVIKEEAIMWPGHQTEVLVSVCSNSCAPGFRKAVRRGQPLCCFDCVPCDSGKISNETDSLDCIACSEDYWSNADGTVCIPKVVEFLSHDAMGLTLTVIAVAGACLTLAVFSVFLYYKNTPVVRINNSELSFFILLSLTLCFLCALIFIGEPTSWSCMLRHTAFSITFSLCISCILGKTLVVLAAFTATRPGNNLMKWLGPTQQRIIIFCCTLIQVLICTVWLVASPPFPYRNTKYQQSKIILDCSVGSDLAFWCVLGYIGLLACVCFFLAFLARKLPGNFNEAKYITFSMIIFCAVWLAFVPAYVSSPGKFTTAVEIFAILASSFGLLLCLFTPKVYIILVKPEKNTKQHLMGKDK", "length": 859 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AV03-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYNNVLLIVTLQCIITRLYVVYGNRLGSCILQGDPQPPVLFDEGDFIIGGAFSIHYYLRTEKHTYTMRPQSLECSGSMDFRELRFARVLQFAIQEINNSSDLLPGITLGYRIYDSCGSVPMAVKLSFQLANGLDLIFNDNDSCSKSAAVAALVGESGSTPSISISRLYGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEEEGICVEYSEAYYRTQPRSKLMRVADVIRRSTARVIVAFMASGDMRLLLEELSQQPLPPMQWIGSEAWFTDPEMLRFNMCIGGVGFAIPRSVIPGFRTFLLDLSPQRAMKFPLLTEFWESSFSCSLKQQTGPSTGMPACDGTEDLGRLKNPYTDTSQLRISNMVYKATYAIAHALHGIICNEKKCNKNIKIEPREVLDKLKQVKFSKNNYSVSFDAYGDPVAVYELVNWQLQKDGSIDFVTVGKYDSSQPKGKEFSLSRAIIWYDGTEEVPVSVCSESCPPGTRKAVQKGRPVCCYDCINCADGEISNDTDCLDCHECLSDYWPNNEKNKCLRKPVEFLSWDEILGIILAAFSVAGSLVALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPSQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFGLILCIFAPKFFIIIFRPERNTKKHIMGKVPSKAL", "length": 856 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B2Z8-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcg8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLFLYSVLSLYHLNTKAENTLCQMIGNPKYPLLSKDGDITIGALFVIHSEVSLPSFAFTQKPNLLSCSSLNIKDFRLAQTMIFAIEEINKNTNLLPNISVGYQIYDTCGSRFHSMSATMALMNGPKNSEGYTCNEQSSVHAIVGETESSNTIILSRTTGPFKIPVISPTATCECLSNRKEFPSFFRTIASDYHQSRALAYIVKHFGWTWVGAVNSDNDYGNNGMATFQKTAKEVQICVEYSVKFIRTETEKIRNVVNVIKKGTAKVIVAFLTGFEMKSLLEQLSSQNITGLQMIGVEAWITSKTLITSKSFHVLGGSLGFAVRKIQIEGFADYVMKAFWDTAFQSFSNADLNYSQYQDLLLVKNYNEDVLEQRFVSYVYKAVYALAHSLHSLLRCTEQGGCGKALTIQPHQLVEALRKVNFTVKMGDQVWFDSTGGVIAQYDVVNWQQNSDGSVQFQSVGYYDASLSPDQRFMLNTEKIVWAGGQLEKPRSVCSESCPPGTRKASQKGRPVCCHDCIPCADGEISNETDSNNCKQCPGEYWSNANKNKCVTKAVEFLSFTEVMGIILVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSIPFIGRPTQWSCMLRHTAFGITFVLCISCILGKTIVVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTLIQGLICVIWLTKSPPFPYKNMKYFQEQIILECSVGSTIGFWAVLGYIGLLAVLCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKLTVAVEIFAILASSFGLLFCIFAPKCYIILLQPEQNTKQQMMAKTPSKI", "length": 832 }, "evidence": [ { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PAH3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTKKSELLLLMVLVTHGICVPNLAQVCRLLGQPALPLLSEERNINIGAIFSLHKSALLKSHNFTSKPKQTTCGGLNLREFKFVQTLIFAIEEINNSSLLPGASLGYKIYDSCGSVAQAIFSGMALMNGYEETLSDTSCSTPPAVHAIVGESNSSPTIGLASVVGPFSLPLVSHFATCSCLSNRKRFRTFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGIATFEEAAKQEGICIEYSEAVFKTDPEVQFLKTIEVIKKATTKVVVAFMAFGDFVLLLKVMAQQNITGIQWIGSESWITSRNLAETKEYHFLSGAVGFAIANSKPVGLREFLMNVHPDKELNNELLKEFWETVFLCSFRNSSSGGCTGSEKLSELQNEYTDFSELRIENKVYTAVYAVAHSLHNVLKGFKFFTNSSKKQLPTPQKVLEYLRDVNFTVNTNENIFFDASGDPVARYDLVNWQPTKDGSLQFKLVGIYDSSLPSEQRLQINQESMLWAGNSGQLPVSVCSESCPPGTRKAVQKGRPICCYDCIPCAEGEISNYTDSSDCFPCGLEYWSNESKDRCVLKVIEFLSYTEIMGVGLCIFSFIGVLLTATVSFLFYFYKETPIVRANNSELSFLLLFSLTLCFLCSLTFIGRPTDWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLIQVIICVLWLTMSPPFPFLNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFFARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSAPGKYTVAVQLFAILASSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKS", "length": 849 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PD42-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWITLCIYLYLSLNYICAHSILRTSDSCRLQRRFHLNGMYKDGDVILGGLFQVHFFTVFPEQSFRTEPEPPFCEKFDMESFQQAQTMAFAIEEINKNPNLLPNITLGFHLYDNCVRLGMAFRAAISLASGTEESFQNLNCTGPPPVIGIVGDPSSTPSIAISSLLGLFRVPIVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLIYSDDDYGVYAAQSFHLEMQMFGHCVAFSEILPHNNNQRDIQRIMGVIQASTARVVVVFSTSSFLLPLIDEVASQNMTGRQWIASEAWATSPVYHSPRLLPFLGGTLGIAVRHGEIPGLHDFLLHLGPGNESRNNMLRIFWENMFGCSFEPGVKDTNSEIKLCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHGLHDLMQCEKGRGPFRGESCADITNLKPWQLVHYLQKVNFTTGFGDHVSFDENGDALAIYDVLNWQPSSDGSIQIFTVGVVKERTETGMVLTIDEDAIYWNFETKKSPQSVCSESCSPGTRRATRKGLPVCCFDCLPCRDGEISNTTDAIECMLCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGSCFCVLVMIIFGLHRNTPIVRANNSELSFMLLLSLKMCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGAMKWFGAAQQRCTVLVLTVLQVVICSVWLSTASPTPYKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKNAIMGRETQKR", "length": 867 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PFV7-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcg9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLYLCTLLLFFKLKVSVGNASCKIMGEPKYPLLFKDGDVTIGALFPVHSIETAPSFEFTQKPQLLSCSSVNLRDFRLAQILIFAIEEINRSESLLPKLSLGYKIYDTCSSKLSSMSATMALMNSFEFAGRDKCNGQTSVHAIIGETESSATVILTRTTGPFKIPVISHAASCECLSSRKEYPSFFRTISSDYHQGRALAYIVKHLGWSWVGAVNSDNDYGNYGMAIFLNTAHKEGICVEYSEKFYRTEPEKLKKVVDTIKKSTAKVIVAFISFLEMRLLVEQLSAENITGLQIVGVEGWTTSKSLITPKTLNVLRGSLGFAMRKIYIEGFAEYVLKPFWDTAFPCIPNQRNDSWVILNCSRYQDLLVLKNYIEDVPEHRFSINVYNAVYAVAHALHSLFKCKEQEGCEKDLLTQPQQVVDALKKVNFTVKMGDRVWFDSTGATLAQYEVVNWQQNSDGSVNFKKVGYYDASLPPDQRFVLNIKEILWAGGNLKKPRSVCSESCPPGTRKAAQKGRPICCYDCIPCADGEISNDTDSNNCKQCQGEYWSNADKNKCVQKSVEFLSFTEVMGIVLVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTQWSCMLRHTAFGITFVLCISCVLGKTLLVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTFIQVLICVLWLSISPPFPHKNMKYYEEKIILECSLGSTIGFWAILGYIGLLAALCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSISLLLCIFAPKCYIILLKPEQNTKQYMLGKTTSKFY", "length": 839 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPM0-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcg12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVFFCTLLIFFQLYAKAEKPICIMMGDPKYPLLSKEGDISIGAVFPVHSIETLPLFKFTQKPQLLSCSSVSIRDFRMAQIMAFAIEEINRNESLLPNVSLGYQIYDTCGSGLSLMGANMALMNVQEFASRGSCNGQSPVHAIIGETESSNTVILSRTTGPFKIPVISPSASCECLSNRKEYPYFFRTIASDYHQSRALAYIIKYFGWSWVGAVNSDNDYGNHGMAIFLSTAEKEGVCVEYSVKFQRTEPEKLKKVVDTIKKGTSKVIVAFLTEFEMKNLLEYLIIQNVTGLQVIGVEAWITANSMIKPNSFHVLGGSLGFAVKKLNIEGFEDYVTKAFWETAFPCSQTSQKENSQYKLICNIYRDLLVLKNDNKDVPEQRYASNVYKAVYAVAHSLHNILKCRENGACETDMKIQPQQVVEALRKVNFTIKMGDCVWFDSTGAVVAQYEVVNWQPDYNGSIQFKPVGYYDASLPPNQRFVINTENIIWAGGQLKKPRSVCSENCPPGTRKAVQKGRPVCCYDCIPCAEGEISNETDSNNCKQCPGEYWSNAEKNKCVLKAVEFLSFKELMGIVLVFFSLLGAGLTTLVAILFYSKKDTPIVKANNSELSFLLLFSLMLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSDVMKWFGPIQQRLSVLVITIVQVLICVLWLAVSPPLPYKNTKYFKEKIILECSLGSTIGFSAALGYIGLLAILCFILAFLARTLPDKFNEAKFITFSMIIFCAVWITFIPSYLSSPGKLTVAVEIFAILASSFGLLFCIFLPKCYIIMCKPEQNTKLHIIGKLNK", "length": 837 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2U8-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLCEMWITLNICLYMYFNHISGVFTSESCQLQGCFKLNGMYQDGEFIIGGLFEVQNLKVFPELSFTNEPELPQCEEFYMASFQQALTMVFAINEINSNSKLLPNITLGYQIYDNCLRLGVAFRAAMSLVSGTEESSNLSCTGPPPVIGIVGDPGSTQSITISSVLGLYRVPMVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLLYSNDDYGIYAAQSFQQEMQILGGCVAFSEMLPYDNNGRDIQRIAGVIQKSTAKVVVAFSTDLASLMDELLLQNVTGKQWIASEAWTTTPVLQTPQYLPLLGGTLGIAIRRGQIQGLYEFLKNLRPDKNPKNSTIRIFWETMFGCKFEVGGKKVDEQQERGRNKCSGQEDLNNSETAYTDVSELRASYNVYKAVYALAHALHDLVKCEEGKGPFTGNSCADISNLKPWQLVHYIQNVKFTTGFGDHVSFDENGDALAIYDVMNWHPRSDGSIIVHVVGVYEEAILGKVLTLDEDALFWNFETKKPPDSVCSESCPPGTRRARKKGLPVCCFDCLPCGDGEISNTTDSPECFICPEDFWSSPENDRCVPKEMEFLSYDDPLGISLTTASLLGTCFCVLVLVIFAYHHNTPVVRANNSELSFLLLVSLKFCFLCVLLFIGRPRLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKTSRPEGKTSIKWFGSAQQRGTVIALTSAQVAICTVWLSSASPTPHKNNQYIHSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFMARKLPDNFNEAKFITFSMLIFCAVWIAFVPAYASSPGKYAVAVEIFAILASSFGLLAAIFAPKCYIIILHPERNTKKAIMGRSTQNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2V5-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcx2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALLCATLLMVWFLMYLSVQSQYNSKVRCVFQGDDDTNTFYQGGDVVLGGLFPLHFSPISSLSSYKTKPTPTTYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPDKDSGQSCEDTRKQPSPVVVGEASSGISMAVLRSLGCFKIPLVSYFASCSCLSNKKEFPAFMRTMPSDLFQIKALAKLVHYFQWTWVGVIGVDTDYARFAIQLFLKESQQLNICLAYVQLYPVALNQDSAEELVRMLKSSSATVIISFSVDSYLYGILKECRRQNVTHLQWIASEAWATSKSLWEEFGDLLKGTLGFAIHRADIPHLGSYLKEIRPQTSHFLSEFWEETFRCRLNGSLNTHAHGEQAQNWPACNGSESLDDVYTTYSDVSQLRVSYNVYKAVYLIAHALHDMSTCVPGKGPFQNGTCGSLFQIQPWQLLYYMKQTNFTTLGEEIRFDENGDPIASYDLMNWQRGSDSSLQLVRVGFYDASLEDDKDLVIDESLIMWHRAEKAPESLCSKSCLPGSRKARQKGKPVCCFDCISCAEGEISNHTDSIECLTCSEDTWPNQSQDQCIPKTLEFLSFQEPLGIILWVFSAFGACAALAVLCVFVMYRKTPVVRGNNIELSFLLLLFLCACFLIGLTFLGKPTDWLCQIRYPAFGISFTLCISCILAKTVVVLMAFRATIPGNNVMKWFGPVKQRSSVILCTCVQALICIIWLTTKPPLASYNSKFMSETIIVECSVGSEIGFWCVLGYVGLLACLCFLMAFLARKLPDNFNEAKFITFSMLIFFAVWITFIPVYLSSSGKYMVAVHVFAILASAFGLLLCIFFPKCYIVLLKPEKNDKKHIMKK", "length": 863 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T5D2-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCYYICVTLMASTGICQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMESFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLHNLTSRQWIASEAWVTAAVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTANTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEESIKLHNIGVVNEVATEMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTRRAMRKGLPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDQCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSLAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6G6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAILLFCLFLSCNFICVTLMVSSGTCQKQGHFTLNGMHQDGDFVIGGLFEIQSYVKVYPEISFRTQPKLPNCDLFYMTSFQQALTMVFAISEINNNPNLLPNITLGYQIYDNCLRLGVAFRAATALISGTEETISDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRLPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAMVQTMRHFGWTWVGLIYSNNDYGIYAAQSFHKEMQLFGHCVAFSEILPQDNNPRVIDHIIGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTGRQWIASEAWVTSTVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETEDKETFGQQIKKVCTGQEDLSITNTPYTDVSGLRAPYNVYKAVYALAHALHDLMQCKEKRGPLSEKNCADITDLKPWQLLSYLKKVNFTTGFGDPVSFDNNGDALAIYDVLNWQPSSEGSIKLHSIGVVNDEVATGMVLRLNKDEIYWNFEAQKAPRSVCSESCPPGTRKAMRKGFPVCCFDCLTCGDGEISNTTDAIKCTVCPDEFWSNFNKDQCVPKEIEFLSYEDPLGISLTTASLLGTCFCALVMIIFAFHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFNSSRPEGKGAMQWFGAAQQRCTVLVLTVLQVVICAVWLSTSSPTPHKNNQYVRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRETKKY", "length": 869 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6Z6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcq17", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLYLSLCLCFKHIYADSIHRLRSCQLQGRFKLNGMYQDGDFILGGLFHVHFFTVFPELSFRMEPQQPYCEKFNMEGLQHAQTMAFAINEINKNPTLLPNITLGYHLYDNCVMLRMAFRAAMSLASGTEDSYSNLNCTGPPPVIGIVGDASSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKHFKWTWVGLLYSGDDYGVYAAQMFHKEMQLSGHCVAFSEILPNDHNPKDIQRIIRVIQGSTARVVVVFALSSFLIPLMDEVVLQNMTGCQWIASEAWATSLEYHTPRFLPFLGGTLGIAIRRGEIEGLHEFLLRIRPSNDTSQNIVRIFWENLFGCRFETGGLKTGREQEKMECTGQEDLSTTNTPYTDVSGLRASYNVYKAVYALAHGLHDLMQCEEGRGPFIGNSCADITSLKPWQLVHYLQNVNFTTGFGDHVTFDKNGDALAIYDVLNWQPSSDGSITVHKIGVVYEGATTGMMLTLDADAIYWNFETKKPPLSVCSESCPPGTRQATRKGLPLCCFDCLPCGDGEFSNTRDAVECMMCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGAMKWFGASQQRCTVLVLTALQVVICAVWLSTASPTPHKNNHYFRSIIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFALLLAIFAPKCYIILLHPERNTKNAIMGRETQNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TDV0-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfck1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRISLGWVVCLVKEMHVNLLLILTLLCIRRLFPAVCGVHLGTCILQGDPQPPSLFSKGDFVIGGTFTIHYYLRTEKRTYTVRPQPLMCSGSMDFRELRFARVLQFAIQEINNSSNLLPGITLGYHIYDSCASVPMVIKVAVQLANGLQLAFNDTDSCAQSSEVLALVGESGSTAAITTSRLFGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEVEGICVEYSEAYYRTQTRNKLQRVADVIRRSTARVIVAFMAAGDMRFLLEELSQQPPPPMQWIGSEAWVTDPQMLRFNLSIGAVGFAIPRSVIPGFRKFLLDLSSEQALKIPVLKEFWESSFGCSLKQHTGYFSGMPACDGTEDLGTLKNPYTDTSQLRISNMVYKATYAIAHALHGIVCNGKLCDKNIKVEPRKVSDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPKGQEFSLNRAIIWYDGTEKVPVSVCSESCPPGTRKAVKKGRPVCCYDCINCADGEINNETDSLDCHKCQPDYWPNAEKIKCLPKPVEFLSWDEILGNTLAAFSIAGSLVALSMALVFYKNRVSPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFSLILLIFAPKCFVIVFRPEENTKRHLLGKVPPKAL", "length": 870 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UVL1-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLTWHRLFIKATPSKVFIINNIHRGELKRNVEMWIIAKICLYLSFSCISVASIFRSGPCQLQGQFRLNGMFQEGDLILGGLFEVHFLTVFPEQSFRTEPEPPYCEQFDMASFQQAQTMVFAIDEINRNPNLLPNITLGYYLYDNCVKLSVAFRAAMALVSGTEESFSSLNCTGPPPVIAIVGDPGSTHSIAISSILGLFRVPMVSYFATCSCLSDRKTYPSFFRTIPSDAFQVRAMVQILKRFGWTWVGLLYSDDDYGIYAAQSFQKEMQLFGACVGFSEMLPRDNNHEDIQSIVEVIQTSTARVVVVFSTEAYLLPLMDEVALKNVTGRQWIASEAWATSPVFHTQHLLPFLGGTLGIAIRRGEIQGLKEFLYYLHPDSNTRNNIVRIFWENIFGCSFEIGGRERKVCTGQEDLKSTNTAYTDVSGLRASYNAYKAVYALAHALHDLMQCEDGRGPFSGNKCADQINLQPWQVVHYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWQPSSDGAISVSTVGVVNEGASMKMVLTLKENSIFWNFKNRKPPQSVCSESCPPGTRQVRRKGLPVCCFDCLPCADGEISNTTDAIECKICPDELWPNPNKDQCVPKEEDFLSFEDPLGISLTTASLLGTCFCALVMVIFSHHRNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPKLWTCQLRHAAFGISFVLCVSSILVKTMVVIAVFKSSRPESKSAMKWFGVAQQRGTVMALTTLQIVICTVWLSMASPKPYKNSLYISSKVVYECDIGSVVGFSLLLGYIGLLAAVSFLFAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYMILFHPERNTKKSIMGRATQIK", "length": 894 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V5L1A2-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSVSMWGYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFSQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSHQSLGKIEETVQKMQKCTSKVVLVFLSNSNFQLILHGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVPSSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPSWLKQGHHI", "length": 845 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AB13A3P1-1", "protein_name": "Olfactory receptor CG7", "gene_name": "olfcg7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSANSLFMVSLTFRMILYFYTILFLRCFQAKTENAFCQIIGEAKYPLLSKDGDVTIGGIFAIHSKETLPSFEFQQKPQPLLCSSVNLRDFRLAQIMIFAIEEINKSENLLPNVSIGYRIFDTCGSRLSSMSATMGLMNELKFAAGETCNGQSPIHAIIGETESSATVILSRTTGPFKIPVISHSASCECLSNRNDYPSFFRTISSDYHQGRALAYIVKYLGWSWVGAVNSDNDYGNYGMAIFLETAQKEGICVEYSVKFYRTETEKLKRVVDTIKKSTAKVIVAFVSFIEMGLLIEQLSIQNITGFQIIGVEGWITSKNYITTNSFHSMGGSLGLALRKIHLEGFLDYVTKSFWSTAFPCSQTEGILPTVGCSKYKDLLPLKNYTEDVPEHRYSSHVYKAIYAVAHSLHSLLKCKEGEDCEKGHATQPQQVVEALKKVNFTVKFGDRVWFDRTGATVAHYEVVNWQQDTDGSFQFKQVGYYDASLPPDQRFVLNIESIIWPGGNLEKPRSVCSESCSPGTRKAAQKGRPVCCYDCVPCADGEISNETDSVNCKQCPREYWSNGEKNKCVLKAIEFLSFTEIMGIVLVCFSLFGVGLTAVVAILFWSKMDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMVFKATLPGSNVMKWFGPTQQRLSVLAFTFIQVLICVLWLTISPPFPNKNMTYYKEKIIIECSLGSTISFWAVLGYIGLLAVLCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSFGLLLCIFAPKCYIIICKPEQNTKQHVMGKTSLKVQ", "length": 851 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TCB3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNFGAGLRTGSRNGNEKWKRMTFCRSSAFCHMFSSTLYLISSMARHAVVLRAGACQLQGRFRLNGMYQDGDVILGGLFEAHFFTLFPELTFRTEPAPPYCEIFNMESFQYAQTMAFAINEINRNPSLLPNISLGYHLYDNCVMLGMALRAAMSLVSGIEESFLNLNCTGPPPIIGVVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMIQLISHFGWTWIGLLYSDDDYGTYAAQSFHQEMQLFGFCIAFSEPLRYDSNPRDIQRLMEVIQASTSTVVVVFSPSTLVIPLMNEVVLQNMTGRQWIASESWATSPVFYTPRFLPFLGGTLGIAIRRGEIEGLREFLLQLRPKNDPRNNMLKIFWENMFGCSFETGPHVKNVCTGQEDLSTTNTPYTDVSELRAANNVYKAVYALAHALHDLMKCEEGKGPFSKNSCAEISNLKPWQLVHYLQKVNFSTRFGDHVSFNKNGDALAIYDVMNWQPGSDRSIRIHTVGVVSEELEKGLMLTLDEDAIYWNFETKKPPQSVCSESCPRGSRRATRKGHPVCCFDCLPCRDGEISNTTDATKCTVCPDDFWSNLYKDQCIPKEVEFLSYNDPLGISLTTASLLGTCFCAFVMVIFVHHHNTPIVRANNSELSFLLLFSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKMAMKWFGAAQQRCTILALTAIQVVICVVWLSTASPTPHKNNLYIRSIIVYECTIGSVTGFSMLLGYIGLLAAVSFLIAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYSVAVEIFAILASSFGLLVSIFAPKCYIILLHPERNNKKAIMGRETH", "length": 888 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0T300-1", "protein_name": "Olfactory receptor CD2 precursor", "gene_name": "olfcd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANTLSLLLLLLLLHGHFLPATVQICDLVGQSALPVLSAERDINIGAIFSIHRNALLRLYPFTSKPEPTTCVRLNLREFKFAQTFIFAIEEINNNTQLLPGVTLGYKIYDACNAISPTLVSGMALINGYENTLSDTSCSQPPAVQAIVGESSSSPTTALAALVGPFNIPVISHFATCACLSNRKRYPSFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGITAFEDAAKQEGICIEYSEAILRTDPQEQFRKTVEVIKKGTSKVVVAFISFGDFAPLVKVIAENNITGLQWVGSESWITSRNLAETKEYSFLSGAVGFAIVNAKLVGLKEFLVNVHPDQEPKNKLLKEFWETAFQCSFSNSDSALCTGSEKLGELKNEYTDVSELRIEHKAYAAVYAVAHTLHNVFKDVKAPNNSKRELPTPQKVLQYMRNLSFTIKTGENIFFDASGDPVARYDLVNWQTAEDGSLQFKHVGIYDSSLPSKQRLQVNQEIMLWAGKSGLLPLSVCTESCLPGTRKAVQKGRPVCCYDCIPCAEGEISNSTDSSDCFSCDLEYWSNEKKDRCILKVVEFLSYAEIMGIILCIVSFIGLLLTVMVTCLFYLHKETPIVRANNSELSFLLLFSLSLCFLCSLTFIGRPTQWSCMLRHTAFGITFILCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLVQVIVCLLWLTLSPPYPYMNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSSPGKYTVAVEIFAILVSSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKL", "length": 848 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0T301-1", "protein_name": "Olfactory receptor CQ19 precursor", "gene_name": "olfcq19", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWVILNISIYLIFNFIMSASILGSNTCQLQGHFRLNEMYHDGDVILGGLFEVDFLTVFPDLDFKTEPEPPYCVQFDMESFQQAQTMAFAIDEINKNPNLLPNITLGYHLFDNCVMLGMAFRAAISMASGTEEFFNNINCTGPPPVIGIVGDSSSTVSIAISSILGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKYFRWTWVGLIYSDDDYGVYAAQSFQQEMQLFGGCVAFSEVLPHDNNLEDIKHITKMIQASTARVIVVFSTPSFLIPLIDELVLQNMTDRQWIASEAWATSFVHHSPRLLPFLKGTLGIAIRRGEIQGLYEFLLRLQPTNDPKNNMIRIFWEIMFGCNFETGGKKNSGDQVINICTGQEDLRTTKTPYTEVSELRASYNVYKAVYALAHALNDLMQCEDGRGPFSVNSCADITNLKPWQLVHYLQNVNFTTDFGDHVSFDKNGDALAIYDVLNWQPSSDGSIRAQTVGVVNEEVATGMVLTLDEDALYWNFESKKPPSSVCSESCAPGTRLATIKGLPVCCFDCLPCGDGEISNITGAVECTMCPDEFWSNLDKDQCIPKEVEFLSYEDPLGISLTTASLLGTCFCVLVMFVFAVHRNTPIVRANNSELSFLLLLSLKMCFLCALLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPESKGAMKWFGAVQQRCTVLVLTAIQVVICAVWLSTASPAPHKNNQYIRSKIVYECAIGSVAGFSMLLAYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIILLHPERNTKKAIMGKEAQNT", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z4N8-1", "protein_name": "Vomeronasal 2, receptor 72", "gene_name": "Vmn2r72", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKISFIFCHLSDPKCFWRIKDTENKIGDIETYCSFSISTKPGYVKNDYFILEIIFSTSVFRVTPKTNHLIFSVYLALEEINMNFHILPNISLVVNVECLRQKYDEKTGLALQSKEFIPNYSCTNERRYLIIFTAPIWAVTTRLGPLMFMYSIPELYCGHFHLSLSDNEQFPHLYQISPKDTSLPLAMVSLMVHFKWNWIGAMITNDDHGIQFLSKLRGEMQKHMVCLSFVFAILTEHSMVRKEFHKNFNLIVRSSAKVVIVYGDYASPIDLVLHWFKSKGLFRIWVSVSQFDIITNLGDFMLYSSSGTFIFSHQKPEISGFQKFIKTVYPSNYSSEFSFAKLWWTYFRCSLPPSNCKTLKNCPTKTVFKWLFRTPLGMAMSDTCYNSYNAIHAVAHSLHEMLLQQVDTWSNNDGKDLEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTEYDIFYIMDFQKHYGFKMKIGRFSGHLPSRQQLYMSKEMMEWATDVDQILPSACNIPCKPGFRKSPEEEMDICCFVCNPCPENEISNMTNMDQCVKCREDQYANEDHTLFLQKVVSILDYREPLGKALAGFALCFSVLTSGIFCVFLKHRETPIVKANNQTLSYVLLISLIFCFICSLLYIGHPTTVICILQQTTFAIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLVSGAPKYIILICTMIQLILCGIWLGTSPPYVDADVHMVHGHIIIVCNKGSVIAFYCVLGYMGSFALTSFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYQSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYIILLRPHINSFRNFRKPHAKTENIS", "length": 856 }, "evidence": [ { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z7M3-1", "protein_name": "Vomeronasal 2, receptor 73", "gene_name": "Vmn2r73", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLIFIFWFLKISYIFCHLSNPRCFWRIKDTKDKLGDKETYCFFSISAKHGYIRNDYFSWNLDKHVTPKTNHLIFSVYLALEEINKNSHILPNISLVVNIECVLLKYGEKTGLGLKHEEFIPNYYCANERRYLIVLTAPIWAVSTKLGPFLFMSRIPELYCGHFHLPLSDNEQFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGVIITNDNHGIQFLSELRGETQKQIVCLSVVIIIQTDDITAYKEYHMNYNKIVMSSAKVVIVYGDHNSPIKFVLFLWKSQGIFRIWVSVSQFDMITPLGDFMLYSASGTLIFSHQQSELSGFEKFIKTVKPSNYSSEFSFAKLWWTYFRCSSLPPSNCKKLKNCPTKTVFRWLFMTPLGMAMSDTCYNLYNAIYAVAHSLHEMLLQQVDTWSENAGKELEFDSWKMFSILKTMQFVNPAGDLVNMNQNLKQEREYDIFYIMDFQKDYGLKMKIGKFSGHLPSHQQLYMSKEMIEWATDMDQILPSICSMPCRPGLRKSPQEGKDICCFVCNPCPENEISNMTNMDQCVKCPEDQYANEDHTLCLQKIVAILDYRDPLGKALAGFALCFCVITSGVLCIFLKHRETPIVKANNQTLSYVLLISLIFCFICSLLYIGHPTIVICVLQQSTFAISFTVAASTILAKTITVVLAFKVTVPGRMRWLLVAGAPKYIILICTMIQLILCGVWLGTSPPFVDADLHMVHGHIIIVCNKGSVIAFYFVLGYMGSIALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWVTFIPVYYSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYNILLRPGKNSSHMFKKLHAKTENII", "length": 851 }, "evidence": [ { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZEQ5-1", "protein_name": "Vomeronasal 2 receptor, pseudogene 67", "gene_name": "Vom2r-ps67", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKIFFLIVVFLLLKLSFLFCHLSDPRCFWRIKDKENYQGDKDIDCFFSIYTEHGYVKNDYFSGNLDKQVTRKTIHLISSVYFAIEEINRNIHILPNISLLVKTECNLFADNVDTVRSLKKKEIIPNYYCKHQRRYLIVLTGPPWLTSYKLGPFLFFSRTPELYCGYFHFRADQEQFPHLYQMSPKDTSLPLAMVSLAVHFRWNWVGVIITDDDQGIQFLSELRTGVEKSTVCVAFVTITTDDRMLYFKMIHKYYHQIITSSAKVVIVYGDKESLIQYNFMLWKSKNVQRLWVSVSQFDMITMIGEFMLHSLHGSIIFSHQHSEMSGFKKFIQTVNPSNYSNDISFAKLWWTFFKCSLPPPNCTTLKNCPSKILSKWFFVSPLGMSMSDICYNLYNAVYAVAHSLHEMLLQHVEIYSDNDGKVVEFNSWKIFSLLKTIQFVNPAGDLVNMNQNIKLGTEYDIFYVMDFRKQEGLKMKIGRFSGHFPNDQQLFMSDEMIEWATDIKQTLVSICSVPCRPGLRKYFQEGKAVCCFDCYPCPENEISNMTDMDDCVKCPEDKYANTDKTNCLKKVVTFLDYEDPLGMTLAGLALWFSALTAIVLCVFLKHRDNPIVKANNETLSYVLLISLIFCFICSLLYIGHPSMARCILQQTTFAIVFSVAASTVLAKTITVVLAFKITLPGRRLRWLLLSGAPNYIIPICTMIQMILCGIWLGISPPFVDADLHMVHGHIIIVCNKGSVIAFYSVLGYMGSLALSSFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFLPVYHSTKGKAMVVVEVFCILTSSAGLLLCIFVPKCYIILLRPQINSFHNFSKMRAKATSIN", "length": 853 }, "evidence": [ { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AB78-1", "protein_name": "Vomeronasal 2 receptor, 43", "gene_name": "Vom2r43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSLILVLLFLKASLLFCTLNDPKCFLRIKDKKNVDGDKEVDCFFSIYAKHGHVKNDFFSGNLDKQLTTKNIHLILSLYFSIEEINSTPQVLPNISLLVKIECNLLADRSKISLSSRKGDYFPNFDCRNQRRYLIVFTGPMWFPTAMLGPLLYISRTPELYYGPFHPLLNTYEQFPYLYQMAIKDTSIAIGMVTLVIYFSWNWVGLMISDDDLGLQFASELREEMQRYDICLAFVTVITYNSKLFLTMAGMYYNQIIMSLAKVVIIYGDIDSFLQVIFRLWQFVDIRRIWIATSQWDIITSNGEFLFNSFHGTLSFSHHYSEISGFKEFIQTVYPLNYSNTISPAKLWWVNFNCFWPSSNCKKLKKCSRKMLLKWLSNNQFEMAMSETNYNLYNAVYAVAHSLHELILQQANTLSNNVEKELEFDSLQVLSSLKKIQFVNPAGDLVNLNQKENLNVDYDIFYTGDFLQSYGIKVKIGNFFKYLTQPQKLLMFDEMVDWATDIRQTLPSICSTPCNPGFRKSPQEGKAVCCFDCNPCPENEISNMTDMDYCYKCLDNQYANSEGTHCLSKTVIFLSYEDPIGVTLACLALCFSALTAVVFGIFLRNQDTLIVKANNRALSYCLLISLIYCFLCSLLFIGKPHMVTCIMQQTIFAVAFTVAVSTVLSKTITVVLAFKFTLPSKKMRWLMTSGTSVLIIPICTMIQLIICGIWLGTYPPYVDSDGHIEHGHILIVCNKGSVTAFYCVLGYLGSIALASFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWLTFLPVYHSTSGKALVIVEVFCILTSTAGLLICIFAPKCYIILLTPKNNSFHTFRHNANVK", "length": 847 }, "evidence": [ { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PW21-1", "protein_name": "Vomeronasal 2, receptor 74", "gene_name": "Vmn2r74", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFLNSVFWLLKISFNFGHLSDPRCFWRIKDTENKLGDKETYCFFTISTKHGYVKNDYFRWNLDKKVTPKTRHLIFSVYLALEEINKNCHILPNISLVVNIECVLDKHDEKTDFLFKSEDLIPNYYCKNERRYLIVLTAPLWAVSSSIGPYLFMSRIPEVSQLYCGHFHLPLSDNEQYPHLHQISRKDTFLPLAMVSLVVHFRWNWIGVIVTNDDHGIQFLSEFRGEMQNKIVCLSFAIIIKTGKFLAVTELHMNYKQILMSSAKVVIVYGYRDSPIIYAFIVWKSQDLFRIWVSVSQLDMITFLGDFLLYASTGTFIFSHQKPEISGFEQFIQRIHPSNYSSEFSLAKQWWTYFRCSLPPSNCKKLKNCSTKTVFKWLFMTPLGLAMSDTCYNIYNAMYAVAHSLHGMLLQQVDTWSKNAGKELEFDSWKMFSILKTLKFVNPAGDLVNMNQNLKQDVEFDVFYIMDFQKDYGLKMKIGRFSEHLPSGQQIYMSKEMIEWATDIDQILPSICTMPCRPGLRKSPQEGKDICCFDCKPCSENEVSNMTNMDQCVKCPEDQYANEDHTVCLQKVVTILDYRDPLGKALAGFALCFSVLTSLVLVVFLKHRDTPIVKANNQTLSFVLLISLIFCFICSLLYIGHPTMAICILQQTTFAIVFTVATSTILSKTVIVILAFKITVPGRRMRWLLESGTPKYIIPICTIIQLILCGIWLGTSPPFVDADLHMVHGHILIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYIILLRPQKNYFYKFRKRRELNLTT", "length": 853 }, "evidence": [ { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q067-1", "protein_name": "Vomeronasal 2, receptor 79", "gene_name": "Vmn2r79", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLTFVFLVLKLSFLFCYLSDPRCFWRIKDRENYLGDKEADCFFSMYTKHGYVKNDYFSENLDKKVTLKTIHLISSVYFAAEEINRNSYILPNTSLIVKIECNLIADNVKRIWSLKKKEIIPNYYCKNQRRYLIVLTGPIWITSYILGPFLYFSQTPELYCGHFHLLLNDQEQFPHLYQMTPKDTSLPQGMVSLAVHFRWNWVGVIITDDDHGIQFLSELRAGMESNTVCLAFVTIITYNRKLYLKMYHKYYHQITMSSAKVVIVYGDKESPLQFNFILWKSENIQRLWVSVSQFDIITMIGEFMLNSVHGTLIFSHQQSEMSGFKQFMQTVHPSNYSNDISLAKLWWTYFKCSLPPPDCKTLKNCPTKTLLKRFFVPPLGMSMSETCYNLYNSVYAVAHSLHEMLLQQVDTCSENDGKVLEFNSWKMFSFLKTIQFVNPVGDLINMNQNRERDTEYDIFYIMDFLKHEGLKMKIGRFSGHFPNGQQLFISDEMIEWATDIKQTIASACSVPCRPGLRKYFQEGKAVCCFDCYPCPENEISNMTDMDQCLKCPEDEYANTDQTNCLKKVVTFLDYKEPLGMALTGLAVLFSSLTVVVLCVFLKHRDTPIVKANNETLSYVLLISLIFCFICSLLYIGYPSMVSCILQQTTFAMVFTVSASCVLAKTITVVLAFKITVPGRRLRWLLLSGAPNYIIPICTTIQMMLCGIWLGISPPFVDADLHMVHGHIIIVCNKGSVIAFYCVLGYMGSLALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFLPVYHSTKGKAMVAVEVFCILASSAGMLLCIFVPKCYLILWRPQINSFHEFRKMHVKNKNIN", "length": 851 }, "evidence": [ { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q281-1", "protein_name": "Vomeronasal 2, receptor 114", "gene_name": "Vmn2r114", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLLADFISPRCFWKMKQNENRDRNQGTGCTFMIHAVQRPVEKEYFSHILNIQTHAENYKNVLALAFSIYEINRNPDILPNMSVRFTISKYNCYWESELMSLIHLSLQNHDILPNYMCKELTRCTMALTRLNWVTTVKLNTILNNFISQQFFQITYGPFHPVLSDHEKFPYLYQMASDHTSLALALVSFIIHFSWNWVGLAISDNDQGIQFLSYLRRVMEKNAVCFAFVNMIPMSMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQIAFQKFDLPKDNGKEHNYSCKKLYSFLRKTQFTNPVGDRVNMNQRDKLQEEYDIFYIWNFPQGLELRVKIGMFSPYFPNGQQVHLSEDMIEWAKGSAQMPTSVCSAECGPGSRKFRMDGMAACSFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNHCIRKTVVFLSYEEPLGVALSLISLFFSAVTIVVLGVIVKHHSTPVVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGVVFTVSVSTVLAKTITVVLAFKITASQRMMKYFLVSGAINYIIPFCILIQVIVCAVWLGASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGRVMVAVEIFSILASSAGMLGCIFVPKCYTILFRPDQNSLEMIRAKSSSRAHIS", "length": 856 }, "evidence": [ { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3F5-1", "protein_name": "Vomeronasal 2, receptor 76", "gene_name": "Vmn2r76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIDMFSFISVFLVLKASMLFCSLNEPKCFLRIKDKKNKDGDKEVDCFFSIYTKHGHMKNEHFSGNLDKQLTTKNIHLILSLYFAIEEINMSPHLLPNISLLVKVECKLLADGSKVSLSSRRGDYFPNYNCGNHRRYLIVLTGPMWLPTAMLGPLLYISRTPEVRRLYYGPFHPLLSSFEHFPYLYQIAIKDTSVAIGMVSLVIYFGWNWVGLMISDDGLGLQFASELREEMQRYDICLAFVTIITYNTKLFLTMTDTYYNQIMMSLAKAVIIFGDKDSLLQVIFRLWQFLDIRRIWVTTSQWDIITSNGEFLFNSFHGTLSFSHHYSEIAGFKEFIQTAHPLNYSNTISLAKLWWLNFNCFLSSSNCKSLKTCSRKMLLKWLSRNHFEMSMSDTSYNLYNAVYAVAHSLNELLLQQANTLSNNVGKGLEFDSLQVLSSLKNIHFVNPAGDLVNLNQKENMNINYDIFYTGNFLQSFGIKVKIGKFFKYFTHPQELLMYEELVDWATDVRQTLPSICSIPCHPGFRKSPQEGKAVCCFDCIPCPENEISNMTDMDYCFKCPDNQYANPEGTHCLSKIVTFLSYEDPMGVVLACLALGFSALTAAVFGIFLRNQDTPIVKANNRALSYCLLISLIYCFLCSLLFIGQPHILTCIMQQTIFAVVFTVAISTVLTKTITVVLAFRFTLPSKRMRWLMTSGASILIIPICTMIQLIICGIWLGTSPPFVDSDGHIEHGHILVVCNKGSVIAFYCVLGYLGSIALTSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWLTFLPVYHSTNGKALVAVEVFCILTSTAGIFLCIFAPKCYIILLKPENKSFHKFRHKNANV", "length": 853 }, "evidence": [ { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3X931-1", "protein_name": "Vomeronasal 2, receptor 65", "gene_name": "Vmn2r65", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSFMSFFLILEYFLLLSVAHPKCFWRIKQNENKVGDVEDNCFFYIYTRQGPLLNDPFNGNPDILLTTRNIHLILALLFAIKQINRNIHILPNISLIVNVNCAKKEDLQMTNMYSNRDATIPNYNCKHGRRILTVLTGPRWFSSAILGPFLHIFAIPQLYYGPFHPLLSDREHYPYLYQMSPKNTFLTLAMTALVVYFSWNWVGLVISDDELGIEFLFKLRGEMHKHKVCIAFVNMIIQNIQLYQKRAEKYYNQILTSSAKVIIIYGDSDILTVHFRLWQHLGIKRLWITTSHWDENTSKGDLLLSSFNGIFIFSHPHSKIPGFKKFIQTVHPSNYSKDTSLARLWWLYFNCSLPSHCKTLKNCSTKILLEWLSRHQFEVSMSEPSYNLYNAVYAVAYALHEMLIQHTEHWQKDIGKELEFYSWKVAPFLENNKFIIPSEYQYRRGKLDTEYDILYAMDLLPALGLNVKIGKFSQHFLHFQQLYIAEDMIDWTIDIRQTLQSVCSVPCSVGFRKFIQKGKAVCCFDCTPCPENEISNMTDMDQCVKCPNDQYANIKQTHCLKKVVTFLAYEDPLGMTLTCLALLFSALTTVILSILLKHQDNPIVKANNRLLSYILLISLIFCFLCSLLYIGHPHMATCILQQTTFAVVFTVAVSTILAKTITVVMAFKITDPRKKIRQMLVTRAPNYIIPICTMIQLILCGTWIGTSPPFVDSDPHFEHGHIIIVCNKGSVIAFYCVLGYLGLLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTKGKAMVVVEIFSILTSSAGLLVCIFFPKCFTILLKQKVNFTQKFSDTHSKIEYNH", "length": 845 }, "evidence": [ { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3XA45-1", "protein_name": "Vomeronasal 2, receptor 69", "gene_name": "Vmn2r69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVIWFLKIKLMFCHLSDPSCFWRIKETENDLGDTETYCLFSISTKQGYVKNDYFSWNIDKKVTPKTNHLIFSVYLALEEVNKNCHILPNISLLVNIECNGRKYDEKTGLALKIENIIPNYSCTNERTYLIVLTAPIWAVSTKLGPFLFMSRIPELYCGHFHPLLSDNEEFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGVIVTSDDQGIQFLSELKGEMQKNIVCLSVAIIIQTEMSMALKELSMNYKHISISSAKVVIVYGDKFSPINYALTLWISQGILRIWVSVSQFDMITILGDFLLYSSTGTFIFSHQQPEIPGFEKFIQTVYPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKTIFTWLFRTPFGMAMSDTCYNSYNAIYAVAHSLHEMLMQEVDTWSNNAGKELEFDSWKMFSILKTLKFVNPAGDLVNMNQNLKQATQYNIFYVMDFQKDYGLKMKIGRFSEHLPSGQQLYMSKEMIEWATDIDQILPSICSMPCTPGLRKSPQEGKDICCFVCIPCPENEISNMTNMDQCVKCLEDQYANEDHTLCLQKVVAILDYRDPLGKALAGFALCFSLLTSVVLFVFLKHRDTPIVKANNQTLSIVLLISLIFCFICSLLYIGHPTMVICILQQTTFAIAFTVATSTILAKTITVVLAFKITVPGRRMRWLLVSGAPKYIILICTMIQLILCGIWLGTSPPFVDADVQMVHGHIIIVCNKGSVIAFYCVLGYMGSVALAGFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWMTFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYFILRPQTNSFHKFRKPHAKTENKS", "length": 850 }, "evidence": [ { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8Z7-1", "protein_name": "Vomeronasal 2, receptor 75", "gene_name": "Vmn2r75", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNTFSLISVFWFLKISIIFCHLSDPRCFWRIKDAKNDLGDKETYCFFSIYTKQGYVKNDYFSWNLDKKVTPKTNHLIFSVYLAMEEINKNGHILPNISLLVNIECGLELYGERTGLAFKSEEFIPNYYCRNHRKYLIVLTTPKWGVSTSLGPLLYISRVPELYCGHFHLLLNDNEQFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGAIVTNDDHGIQFLSELRGEMQKHIVCLSVAIIIQTEKFMALKEFRMNYNKIAMSSATVVIVYGDKDSPIQFTLIMWKSEGIWRIWVSVSQFDMITVIGDFLLYSSTGSFIFSHQQSEISGFEKFIQTVHPSNYSSEFSLAKLWWTYFTCSLPPSNCKKLKNCPIKTVFKWLFMTPIGMSMSDISYNLYNAMYAVAHSVHEMLLQQVDIWSTNAGTELEFDSWKMFSILKTLKFVNPAGDLVNMNQNLKQDTEYDIFYIPNFQKYYGLKMKIGRFSGYLPSGQQLYMSKEMMEWATDMDQILPSICSMPCRPGLRKSPQEEKDICCFVCNPCPENEISNMTNMDQCVKCPEDQYANEDQTLCLQKVVDVLDYRDPLGKSLAGFALCFSVLTSIVLCVFLKHRESPIVKANNQTLSYVLLISLIFCFICSLLYIGHPTMFICILQQTAFAIAFTVAASTVLAKTITVILAFKITVPGRMRWLLVSGAPKYIIFVCTMIQLIFCGIWLGTSPPFVETDVHMTHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLSRKLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIYAPKCYIILLRPQKNSFYKFRKPHSKSENIS", "length": 853 }, "evidence": [ { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T2-1", "protein_name": "Vomeronasal 2, receptor 67", "gene_name": "Vmn2r67", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKISFMFCHLSDPKCFWRIKDTKKNLGDTETYCSFSISTKRGYVKNDYFSWNLDKQVTPKTNHLIFSVYLALEEINMNFHILPNISLVVNIECLRKKYDEKTGLALQTEEFIPNYYCTDERRYLIIFTAPIWAVTTRLGTFMFMYSIPELYCGHFHLSLSDNEQFPHLYQISPKDTSLPLAMVSLMVHFRWNWIGAIVTTDDHGIQFLSELRGEMQKHIVCLSFEITILTEHSMARKEFQRYFNRIVMSSAKVVIVYGDYTSPIDLVLHLCKSKGIFRIWVSVSQFDMITKLGDFMLYSSSGTFIFSHQKPELSGFQQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKIVFKWLFMTPLGMAMSDTCYNLYNAIYAVAHSLHEMLLQQIDTWSNNAGKELEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTDYDIFYIMDFQKDYGFKMKIGRFSGHLPSHQQLYMSKEMMEWATDVDQILPSICSMPCRPGLRKSPEEGKDICCFVCNPCHENEISNMTNMDQCVKCQEDQYANEDHTLCLQKVVSILDYRDPLGKALAGIALCFSVLTSGILCIFLKHRETPIVKANNQTLSYVLLISLVFCFICSLLYIGHPTTVICILQPITFAIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLLSGVPKYIVLICTMIQLILCGIWLGTSPPFVDADVYMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFSILASSAGLLLCIFAPKCYIILLRPQTNSFHKFRKTHSKAENIS", "length": 851 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U5-1", "protein_name": "Vomeronasal 2, receptor 78", "gene_name": "Vmn2r78", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLIVVFLLLKLSFLFCSLSDPRCFWRIKDRENDLGDKETDCFFSIYTKRGYVKNDYFSENLDKKVTLKTIHLISSVYFAAEEINKNIYILPNISLIVKIECNLIADNVKRIWSLKKKEIIPNYYCKNQRRYLIVLTGPIWITSYILGPFLYFSQTPELYCGHFHFLLNDQEQFPHLYQMTPKDTSLPQGMVSLAVHFRWNWVGVIITDDDHGIQFLSELRTGMESNTVCLAFVTIITYNRMLYLKMYHKYYHQITMSSAKVVIVYGDKESPLQFNFILWKSENIQRLWVSVSQFDMITVIRDFMLNSLHGTLIFSHQQSEISGFKQFMQTVHPSNYSNDISLAKMWWTYFKCSLKPPDCKTLKNCPTKTLFKWFFVPPLGMSMSETCYNLYNSVYAVAHSLHEMLLQQVDTCSENDGTVMEFNSWKMFYFLKTIQFVNPAGDLINMNQNRERDTEYDIFYIMDFLKHEGLKMKIGRFSGHFPNGQQLFMSDEMIEWATDIKQTLASACSVPCRPGLRKYFQEGKAVCCFDCYPCPENEISNMTDMDQCVKCPEDEYANTDQTNCLKKVVTFLDYKEPLGMALAVLAVFFSSLTFIILCVFLKHRDTPIVKANNETLSYVLLTSLIFCFICSLLYIGYPTMVSCILQQTTFALVFTVAASCVLAKTITVVLAFKITVPGRRLRWLLLSGAPNYIIPICTTIQMILCGIWLGTSPPFVDADLHMIHEHIIIVCNKGSVTAFYCVLGYMGSLALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWVTFLPVYHSTKGKAMVAVEVFCILASSAGMLLCIFVPKCYLILLRPQINSFHEFRKIHAKSININRM", "length": 853 }, "evidence": [ { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6V1-1", "protein_name": "Vomeronasal 2, receptor 117", "gene_name": "Vmn2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLVSDFIYPRCFWKIKQNEDKNRNQGTECTFMIHAVQRPVEKEYFSHILNIQTHTENHKYALALAFSIYEINRNPDILPNMSLTFKFSNYNCHWKSKYNSFIHLSLQNHDILPNYMCKEFTKCAMALTRLNWATTVKLNTILNNFMSQQFLQITYGPFHPVLSDHEKFPYLYQMASDHTSLALALVSFIIHFSWNWVGLVISDNDEDIQFLSYLRREMEKNTVCFAFVNMIPMSMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQIAFQKLDNLPKDNGKEHNYSCKKLYSFLRKTQFTNPVGDRVNMNRRNKLQEEYDIFYIWNFPQGLGLRVKIGMFSPYFPNGQQVHLSEDMIEWAKGSAQVPTSVCSAECGPGSRKFRMDGMAACCFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNQCIRKTVVFLSYEEPLGMALSLLSLCFSAFTTVVLGVMVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGVVFTVSVSTVLAKTITVVLAFKITASQRMMKYFLVSGAINYIIPICILIQVIVCAVWLRASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYYSTKGKVMVAVEIFSILASSAGMLGCIFVPKCYTILFRPDQNSLEMIRVKSSSNAHVS", "length": 857 }, "evidence": [ { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N702-1", "protein_name": "Vomeronasal 2, receptor 70", "gene_name": "Vmn2r70", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLNSVFWFLKISFIFCHLSDPRCFWRIKDTENNIGDTETYCFFSISTKHGYVKNDYFSWNLDKQVTPKTRHLIFSVYLALEEINDSFHILPNISLVVNIECVLQKYGEKTGLLLRSEKLIPNYYCINERRYLIVLTAPTWAISTKLGPFLFMSRIPEVNQLYCGHFHLPLSNNEQFPHLYQISKKDTSLPLAMVSLVVHFRWNWIGVIITNDDHGIQFLSELRGEMQNNIVCLSVVITIKTQKLVALKELHMNYKQILMSSAKVVIVYGYKDSPIIYALISWKSHGIFRIWVSVSQFDMITIRGDFLLYSSTGTFIFSHQKPEISGFEQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSDCKKLKNCPTKTVFKWLFMTPLGMAMSDTCYNLYNAVYGVAHSLHEMLLQQVDAWSKNAGKELEFDPWKMFSVLKTIQFINPAGDLVNMNQNLRQDVEYDVFYIMDFQKVYGLKMKIGRFSGQLSSGQQLYMSKEIIEWATDIDQILPSICSMPCRPGLRKSPQEEKDICCFGCNPCPENEISNMTNMDQCVKCPENQYANEDHTLCLEKVVAILDYKDPLGKALAGFALCFSVLTSVVLGIFLKNRDTPIVKANNQSLSFVLLISLIFCFICSLLYIGHPTMVICILQQTTFAIVFTVATSTILAKTVIVVLAFKITVPGRRMRWLLEIGAPKYIILICTIIQLILCGIWLGTSPPFVDADVHMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFSILASSAGLLLCIFAPKCYIILLKPQKNSFQKFRKPHAIADNIS", "length": 854 }, "evidence": [ { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B3-1", "protein_name": "Vomeronasal 2, receptor 68", "gene_name": "Vmn2r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVIWFLKVKLMFCHLSDPKCFWRIKDTENNLGDTETYCSFSISTRHGYVKNDYFSWNLDKKVTPKTNHLIFSVYLALDEINMNIHILPNISMVANIECFLQKDGEKTGLALQRKEFIPNYYCTDERRYLIIFTAPIWAVTTRLGPLMFMYSIPELYCGHFHLSLNDNEQFPHLYQISPKDTSLPLAMVSLMVHFRWNWIGAMITNDDHGIQFLSKLRGEMQKHIVCLSFVITILTEHSMAHKEFQRYFNRIVMSSAKVVIVYGDYTSPIDLVLHLCKSKGIFRIWVSVSQFDMITYLGDFMLYSSSGTFIFSHQKPELSGFQQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPFNCKKLKNCPTKIVFKWLFMTPLGMAMSDTCYNLYNAIHAVAHSLHEMLLQQVDTWSNNAGKELEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTEYEIFYIMDFQKDYGLKMKIGRFSGHLPSRQQLYMSKEMMEWAIDVDQILPSICSMPCRPGLRKSPQEEKDICCFVCNPCLENEISNMTNMDQCVKCREDQYANEHHTLCLQKVVSILDYRDPLGKALAGIALCFSFLTSVVLCIFLKHRETPIVKANNQTLSYVLLISLVFCFICSLLYIGHPTAVICILQQTTFVIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLVSGAPKYIILICTMIQLILCGIWLGTSPPFVDADAHMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYIILLRPDINSFQKFRKPHANAENIS", "length": 851 }, "evidence": [ { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B7-1", "protein_name": "Vomeronasal 2, receptor 77", "gene_name": "Vmn2r77", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEMFSLIVFFLVLKLSFLFCYLSDPRCFWRIKDRENYLGDKEADCFFSIYTKRGYVKNDYFSENLDKKVTLKTIYLISSVYFAIEEINRNIHILPNISLLVKIDCNLIEDNVERVWSLKKKEIIPNYYCKNQRRYLIVLTGPIWITSYILGPFLYFSRTPELYCGYFHLLLSDQEQFPHLYQMTPKDTSLPLAMVSLAVHFRWNWVGVIITDDDHGIQFLSELRTGMERNTVCLAFVTSITYDKMLYLKMTHKYYHQIIMSSAKVVVVYGDKESPLQLNFMLWKSINIQRLWVSVSQFDMITMMGDFMLNSIHGTLIFSHQQSEMSGFKHFIQRVNPSNYSNDISLAKLWWTYFKCSLPPPDCKTLKNCPTKTLFQWFFEPPLGMSMSETCYNLYNSVYAAAHSIHEMLLQHVDTSSENDENVLEFNSWKMFSFVKNIQFVNPAGDLVNMNQNRKLDTEYDIFYITDFLKHEGLKMKIGRFSGHFPNGQQLFISDEMIEWATDIKQTLASICSVPCRPGLRKYFQEGNSVCCFDCYPCPENEISNMTDMDQCVKCPEDEYANTNQTKCFKKVVTFLAYEDPSGMALAVLAVCFSVLTSVVLCVFLKHRNTPIVKANNETLSYVLLTSLIFCFICSLLYIGYPTMVSCILQQTTFAIVFTVAASCVLAKTITVVLAFKITVPGRRLRWLLLSGAPNYIIPICTMIQMILCGIWLGTSPPFVDADLHMVHGHIIIVCNKGSVIAFYCVLGYMGSLALSSFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFLPVYHSTKGKAMVAVEVFCILASSAGMLVCIFLPKCYIILLRPQINSFHDFRKIHVKVININ", "length": 854 }, "evidence": [ { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2D8-1", "protein_name": "Vomeronasal 2, receptor 71", "gene_name": "Vmn2r71", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKVNFIFCHLSDPRCFWRIKETENKLGDKETFCLFSISTKQGYVKNDYFSWNLDKQVTPKINHLIFSVYLALEEINKNCHILPNISLLVNTECNGRKYDEKTGLALKSEKIVPNYSCTNERRYLIVLTAPIWAVSTKLGPFLYISRIPELYCGHFHLLLSDKGQFPHLYQISPKDTSLPLAMVSLFVHFRWNWIGVIITNDDHGIQFLSELKGDMQKSIVCLSVAIIIQTEVYMALKELHMNYKKILMSSAKVVIVYGDKDSPIKYVLTAWKSQGIFRIWVSASQFDMITILGDFLLYSYTGTFIFSHQQPEIPGFEKFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKSVFAWLFRTPLGMAMSDTCYNSYNAIYAVAHSLHEMLLQEVDTWSKNAGKELEFDSWKMFSILKTLKFVNPSGDLVNMNQNLKQDTEYDIFYIMDFQKDYGLKMKIGRFSGHLLSGQQLYMAKEMMEWATDIDQILPSICSVPCSPGLRKSPQEGKDICCFVCNPCPENEISNMTNMDQCVKCLEDQYANEDHTLCLQKVVVIFDYRDPLGKALAGFALCFSVLTSVVLFVFFKHRDTPIVKANNQTLSFVLLISLIFCFICSLLYIGHPTMVTCIVQQITFAIGFTVATSTILAKTVIVVLAFKITVPGRRMRWMPESGAPKYIILICTMIQLILCGIWLGTSPPFVDADVQMVHGHIIIICNKGSVIAFYCVLGYMGSLALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKIMAVVEVFCILASSAGLLLCIFAPKCYIILLRPQTNYFHKFWKSHANSENKS", "length": 851 }, "evidence": [ { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-641", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-641#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1LV89-1", "protein_name": "Olfactory receptor CQ3 precursor", "gene_name": "olfcq3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLNICLHLSFIFISVNSDSCQIQGHFKLNRMYKDGDYIIGGLFEVQHLKVFPELSFRMEPEQPKCEEFYMSSFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCLKLVVAFRAATTLISGTEETFSNFNCTGPPPVIAIVGDPGSTHSIAVSSVLGLFHVPLISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMVQILKYFGWTWVGVLYSDDDYGIYAAQSFQQEMQRFKGCVAFSEIVPYDNHRDIQRIVAVIKASTARVVVAFSTDLLPLMEELLQQNVTGRQWIASEAWSTSPVLHLPRFVPLVRGTLGIAIHRGKIKGLHEFLLHIQPDNDPTNNMVRIFWENMFGCSFEKGNGYGEKMCTAQEDLNITVNEYNDVSELRASYNVYKAVYALAHALHDLMQCEEGRGPFSGNSCADITKLKPWQMVPYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWHPSSDGLIVVRTVGVVDEGASAGRVLTLDEDAIYWNFETKKPPRSVCSESCPPGTRRAMRKGLPVCCFDCLPCADGEISNMSDATECTSCPNEFWSSPKKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVLAVFAHHHNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAMFGISFVLCVSSILVKTMVVIAVFKSSRPEGKSAVKWFGAVQQRGTVLVLTAVQIVICVVWLSTASPTPHKNILYVRSKIVFECSIGSMAGFAILLGYIGILAAVSFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFIPAYVSSPGKYSVAVEIFAILASSFGLLVAIFVPKCYIIILHPERNTKKAIMGRTAEK", "length": 855 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUY1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUY1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 348, "end_pos": 350, "annotation": "n_glycosylation_sequon" }, { "start_pos": 557, "end_pos": 559, "annotation": "n_glycosylation_sequon" }, { "start_pos": 628, "end_pos": 630, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UUY1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUY1" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 594, "end_pos": 859, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 294, "end_pos": 296 }, { "start_pos": 348, "end_pos": 350 }, { "start_pos": 557, "end_pos": 559 }, { "start_pos": 628, "end_pos": 630 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UUZ9-1", "uniprot_ac": "A0A8N7UUZ9", "uniprot_id": "A0A8N7UUZ9_DANRE", "mass": { "chemical_mass": 96327.0, "monoisotopic_mass": 96327.0 }, "refseq": { "ac": "XP_685582", "name": "voltage-dependent calcium channel beta subunit-associated regulatory protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685582" }, "gene_names": [ { "name": "cbarpb", "type": "recommended", "evidence": [ { "id": "A0A8N7UUZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUZ9" } ] }, { "name": "cbarpb", "type": "synonym", "evidence": [ { "id": "XP_685582", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685582" } ] } ], "protein_names": [ { "name": "Voltage-dependent calcium channel beta subunit-associated regulatory protein", "type": "synonym", "evidence": [ { "id": "A0A8N7UUZ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUZ9/entry#names_and_taxonomy" } ] }, { "name": "voltage-dependent calcium channel beta subunit-associated regulatory protein", "type": "synonym", "evidence": [ { "id": "XP_685582", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685582" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_685582.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_685582", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685582" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUZ9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cbarpb", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUZ9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050208-507", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-507", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUZ9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UUZ9", "database": "AlphaFoldDB", "categories": [] }, { "id": "557421", "url": "https://www.ncbi.nlm.nih.gov/gene/557421", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037658", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037658", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:557421", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557421", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UUZ9", "url": "https://www.orthodb.org/?gene=A0A8N7UUZ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28597", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28597", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28597:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28597:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_685582", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685582", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UUZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUZ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUZ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050208-507", "url": "https://zfin.org/ZDB-GENE-050208-507", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSNDSAILTNSTAEPPTNGTLSSETQNGYVLLLVLLSIFVGGTLVLLSVLLIVCRRCCEGDRRHAWFIVCLRASDDTEKSNTTYIEEAQPVHEITIRVDESDCLSAASSHDMETERFLSTGTTGRRVSFNEAALFDHSKKTQEKGRRYTLTEGDFHHLKNARLTHLHLPPPALQILTIHECESSENSLAMMTRPVAKSSLSIFQPPVCSLPQTALTSRTLSPSSALPGDTLNSTVDTTFCESITKAGAEPSSPCLLEVRGGVGRGADIMGNGREAASASATALSSSGGVSQGPMLQFFTKLRRHASLEGASPYFKIKKWKFDSSQRASSLDMRGSPKRRQFQRQRAASESMDQEEHDAHHIDLIQYIARTKDITYCPARASPRLLSPPSTPPPPLGRLEVEVMVEPSCSRALGPGVIGLTSEPPDESLGMGFHQESLEPQTLYRDIWTLRASLERYVSSDQSSNNDRDSVRSDAESVCSLGGKYEMGGLPRYPSQDIGDEMEGDADLPLEESSEKGRKQDSVDSERGSDGEPGNRKLLQMDSGYASIEAPSRAPEELRLFGSSSSSSKDGSAMERRHFFSSGHKGTVCESFDTDILDEELEEEPTGASGGVDGVETSESTMLWSPYGQMFTQRDAQPHPPVLSRRDYSIDEKTEALFHEFLRHDPQFDQQESPLRSKHRSRVHLRKQWQRSKQYSDPGQRFQTSFDRYRTPLRRGETVNYPLETSYQSTLPRIISAPDEESSEGATSTPEIPKGDQDATTDVDPDKTRISSSSESSGIIHKKEFLEASKPLPMTDIAGEQSVGRENSRQVLPPPDEPTPECTSYGPQTITEELSDKLAATLEERLYSDLRRTRETPECSTVTMTHTSPDHSPV", "length": 873, "header": "tr|A0A8N7UUZ9-1|A0A8N7UUZ9_DANRE Isoform 1 of Voltage-dependent calcium channel beta subunit-associated regulatory protein OS=Danio rerio OX=7955 GN=cbarpb PE=4 SV=1 CANONICAL=A0A8N7UUZ9-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UUZ9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUZ9/entry#A0A8N7UUZ9-1", "sequence": { "sequence": "MSNDSAILTNSTAEPPTNGTLSSETQNGYVLLLVLLSIFVGGTLVLLSVLLIVCRRCCEGDRRHAWFIVCLRASDDTEKSNTTYIEEAQPVHEITIRVDESDCLSAASSHDMETERFLSTGTTGRRVSFNEAALFDHSKKTQEKGRRYTLTEGDFHHLKNARLTHLHLPPPALQILTIHECESSENSLAMMTRPVAKSSLSIFQPPVCSLPQTALTSRTLSPSSALPGDTLNSTVDTTFCESITKAGAEPSSPCLLEVRGGVGRGADIMGNGREAASASATALSSSGGVSQGPMLQFFTKLRRHASLEGASPYFKIKKWKFDSSQRASSLDMRGSPKRRQFQRQRAASESMDQEEHDAHHIDLIQYIARTKDITYCPARASPRLLSPPSTPPPPLGRLEVEVMVEPSCSRALGPGVIGLTSEPPDESLGMGFHQESLEPQTLYRDIWTLRASLERYVSSDQSSNNDRDSVRSDAESVCSLGGKYEMGGLPRYPSQDIGDEMEGDADLPLEESSEKGRKQDSVDSERGSDGEPGNRKLLQMDSGYASIEAPSRAPEELRLFGSSSSSSKDGSAMERRHFFSSGHKGTVCESFDTDILDEELEEEPTGASGGVDGVETSESTMLWSPYGQMFTQRDAQPHPPVLSRRDYSIDEKTEALFHEFLRHDPQFDQQESPLRSKHRSRVHLRKQWQRSKQYSDPGQRFQTSFDRYRTPLRRGETVNYPLETSYQSTLPRIISAPDEESSEGATSTPEIPKGDQDATTDVDPDKTRISSSSESSGIIHKKEFLEASKPLPMTDIAGEQSVGRENSRQVLPPPDEPTPECTSYGPQTITEELSDKLAATLEERLYSDLRRTRETPECSTVTMTHTSPDHSPV", "length": 873, "header": "tr|A0A8N7UUZ9-1|A0A8N7UUZ9_DANRE Isoform 1 of Voltage-dependent calcium channel beta subunit-associated regulatory protein OS=Danio rerio OX=7955 GN=cbarpb PE=4 SV=1 CANONICAL=A0A8N7UUZ9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 390, "start_aa": "Thr", "end_pos": 390, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr390", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 605, "start_aa": "Thr", "end_pos": 605, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr605", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 818, "start_aa": "Thr", "end_pos": 818, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr818", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:557421", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557421", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1MAS1-1", "protein_name": "CACN subunit beta associated regulatory protein", "gene_name": "Cbarp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQPTATMATAAATTATVALTTSWDNATNRPTAEPDPILDNYVLLVVVMSLFVGGTLVVLSGVLLLCKRCWEVHQRFNRAMEETEKTTTTYLDNGTHPIQDPDCRGEDPEGQDTETERFLATTSTGRRVSFNEAALFEQSRKAQDKGRRYTLTEGDFHHLKNARLTHLHLPPLKIATIHECDSGEASAAATPHPHPASTPKDSLAIFQPPGKSLTGHSVGPSSALPGDPYSSVDFSEISPSASSDSGEGTSLDAGTRGTKAAGPETAPGEMGTGSSGAGTVLQFFTRLRRHASLDGASPYFKVKKWKLESSQRASSLDTRGSPKRHHFQRQRAASESMEQEGDIPHADFIQYIASAGDSVAFPPPRPFLASPTSPPPTLGRLEAAEAAGGGSPETPPEHGISLGPEHAQQQDPQQEQDAEHAQCSYRDLWSLRASLELHAATASDHSSSGNDRDSVRSGDSSGSGSGGGGAAPAFPPPPESPPALRPKDGEARRLLQMDSGYASIEGRGAGDEVSELPAPARSPPRSPRAWPRRPRRDYSIDEKTDALFHEFLRHDPHFDDAPRHRARAHPHTHARKQWQQRGRQHSDPGGARVATPPGATRPTRAPLRRGDSVDCPPEGRAPPITGDDPSIPVIEEEPGGGGSGCPGSGLCVEPAGALLDKLAASLDERLFSPRLAEPVASSPVLIVAAAAPTSPDHSPA", "length": 700 }, "evidence": [ { "id": "RGD:1307185", "url": "https://alliancegenome.org/gene/RGD:1307185#orthology", "database": "AGR" }, { "id": "MGI:1354170", "url": "https://alliancegenome.org/gene/MGI:1354170#orthology", "database": "AGR" }, { "id": "HGNC:28617", "url": "https://alliancegenome.org/gene/HGNC:28617#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-507", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-507#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66L44-1", "protein_name": "Voltage-dependent calcium channel beta subunit-associated regulatory protein", "gene_name": "Cbarp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQPTATMATAAATTATVALTTSWDNATSRPTAEPDPILDNYVLLVVVMSLFVGGTLVVLSGVLLLCKRCWEVHQRFNRAMEEAEKTTTTYLDNGTHPIQDPDCRGEDPEGQDTETERFLATSSTGRRVSFNEAALFEQSRKAQDKGRRYTLTEGDFHHLKNARLTHLHLPPLKIATIHECDSGEASAAATPHPATTSKDSLAIFQPPGKTLTGHSVGPSSALPGGPYNSVDFSEISPSTSSDSGEGISLDAGTRGAKAAGPETVPGEMGTGSSGSGTVLQFFTRLRRHASLDGASPYFKVKKWKLEPSQRASSLDTRGSPKRHHFQRQRAASESMEQEGDVPHADFIQYIASAGDSVAFPPPRPFLASPTSPPPTLGRLEAAEAAGGASPETPPEHGISLGPEHAQQQDPQQEQDAEHAQCSYRDLWSLRASLELHAATASDHSSSGNDRDSVRSGDSSGSGSGGGGAAPAFPPPPESPPALRPKDGEARRLLQMDSGYASIEGRGAGDEVSELPAPARSPPRSPRAWPRRPRRDYSIDEKTDALFHEFLRHDPHFDDAPRHRTRAHPHTHARKQWQQRGRQHSDPGGARAATPPGVARPTRAPLRRGDSVDCPPEGRALPITGDDPSIPVIEEEPGGGGGGCPGSGLCVEPAGALLDKLAASLDERLFSPRLAEPVASSQVLIVAAAAPTSPDHSPA", "length": 698 }, "evidence": [ { "id": "RGD:1307185", "url": "https://alliancegenome.org/gene/RGD:1307185#orthology", "database": "AGR" }, { "id": "MGI:1354170", "url": "https://alliancegenome.org/gene/MGI:1354170#orthology", "database": "AGR" }, { "id": "HGNC:28617", "url": "https://alliancegenome.org/gene/HGNC:28617#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-507", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-507#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N350-3", "protein_name": "Voltage-dependent calcium channel beta subunit-associated regulatory protein", "gene_name": "CBARP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQPTATMATAATTTTTTTATVALTTSWDNATGRPTAEPDPILDNYVLLVVVMSLFVGGTLVVLSGVLLLCKRCWDVHQRLNRAMEEAEKTTTTYLDNGTHPAQDPDFRGEDPECQDAETERFLSTSSTGRRVSFNEAALFEQSRKTQDKGRRYTLTEGDFHHLKNARLTHLHLPPLKIVTIHECDSGEASSATTPHPATSPKATLAIFQPPGKALTGRSVGPSSALPGDPYNSAAGATDFAEISPSASSDSGEGTSLDAGTRSTKAGGPGAAAGPGEAGPGSGAGTVLQFLTRLRRHASLDGASPYFKVKKWKLEPSQRAASLDTRGSPKRHHFQRQRAASESTEQEEGDAPQEDFIQYIARAGDAVAFPHPRPFLASPPPALGRLEAAEAAGGASPDSPPERGAGSAGPEQQQPPLEPDAERDAGPEQAQTSYRDLWSLRASLELHAAASDHSSSGNDRDSVRSGDSSGSGSGGAAPAFPPPSPPAPRPKDGEARRLLQMDSGYASIEGRGAGDDTEPPAAPARPRSPRAWPRRPRRDYSIDEKTDALFHEFLRHDPHFDDTPAAARHRARAHPHARKQWQRGRQHSDPGARAAPALAGTPAPPAGAARPARAPLRRGDSVDGPPDGRTLGGAGDDPAIPVIEEEPGGGGCPGSGLCVLPSGSVLDKLAAGLDERLFPPRLAEPVVATPALVAAAPTSPDHSPA", "length": 705 }, "evidence": [ { "id": "RGD:1307185", "url": "https://alliancegenome.org/gene/RGD:1307185#orthology", "database": "AGR" }, { "id": "MGI:1354170", "url": "https://alliancegenome.org/gene/MGI:1354170#orthology", "database": "AGR" }, { "id": "HGNC:28617", "url": "https://alliancegenome.org/gene/HGNC:28617#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-507", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-507#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUZ9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transmembrane transporter binding", "id": "GO:0044325", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044325", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUZ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of calcium ion-dependent exocytosis", "id": "GO:0045955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045955", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UUZ9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 390, 605, 818 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 18, "end_pos": 20 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 3, "end_pos": 5 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UV06-1", "uniprot_ac": "A0A8N7UV06", "uniprot_id": "A0A8N7UV06_DANRE", "mass": { "chemical_mass": 36405.0, "monoisotopic_mass": 36405.0 }, "refseq": { "ac": "XP_685934", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685934" }, "gene_names": [ { "name": "LOC557729", "type": "recommended", "evidence": [ { "id": "A0A8N7UV06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV06" } ] }, { "name": "LOC557729", "type": "synonym", "evidence": [ { "id": "XP_685934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685934" } ] } ], "protein_names": [ { "name": "HIT domain-containing protein", "type": "recommended", "evidence": [ { "id": "A0A8N7UV06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV06/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_685934", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685934" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_685934.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_685934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685934" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV06", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV06" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC557729", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV06", "locus": {} } ], "crossref": [ { "id": "A0A8N7UV06", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UV06", "database": "AlphaFoldDB", "categories": [] }, { "id": "557729", "url": "https://www.ncbi.nlm.nih.gov/gene/557729", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011146", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011146", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036265", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036265", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:557729", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557729", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UV06", "url": "https://www.orthodb.org/?gene=A0A8N7UV06", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46648", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46648", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46648:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46648:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_685934", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685934", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "67916", "url": "https://www.rhea-db.org/rhea/67916", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UV06", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UV06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV06-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MRRWALSGSAVSLILNALLGRMSWALQEPLVIWESADLLAYLHPSPWTPGVAVLTCKSPCAGGLFHLPEDLFLRLLLGARSVSRRLCAGLSVQRCALVHTPQKHGNTQLLIVPLHGLSADWRPHLAADEEFNEFDPGYISSKSGPRWTDDDLEAVKNRICKPSAQQNYTFLGDPSDDGLFPRIIRGEAQQWRVWEDDEHVAFLTPFPNSPGLTVLVPRRPLSSDVLSLQVEEYKQMVLATREVSCLLEAGLGAWGVGLIFEGFEIDYAHAKLIPLVCADDGAQMSPCSSPPELFQKYPGFVTSLSGPAASRGSLKEIHDRITHTASVDCND", "length": 331, "header": "tr|A0A8N7UV06-1|A0A8N7UV06_DANRE Isoform 1 of HIT domain-containing protein OS=Danio rerio OX=7955 GN=LOC557729 PE=3 SV=2 CANONICAL=A0A8N7UV06-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UV06-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV06/entry#A0A8N7UV06-1", "sequence": { "sequence": "MRRWALSGSAVSLILNALLGRMSWALQEPLVIWESADLLAYLHPSPWTPGVAVLTCKSPCAGGLFHLPEDLFLRLLLGARSVSRRLCAGLSVQRCALVHTPQKHGNTQLLIVPLHGLSADWRPHLAADEEFNEFDPGYISSKSGPRWTDDDLEAVKNRICKPSAQQNYTFLGDPSDDGLFPRIIRGEAQQWRVWEDDEHVAFLTPFPNSPGLTVLVPRRPLSSDVLSLQVEEYKQMVLATREVSCLLEAGLGAWGVGLIFEGFEIDYAHAKLIPLVCADDGAQMSPCSSPPELFQKYPGFVTSLSGPAASRGSLKEIHDRITHTASVDCND", "length": 331, "header": "tr|A0A8N7UV06-1|A0A8N7UV06_DANRE Isoform 1 of HIT domain-containing protein OS=Danio rerio OX=7955 GN=LOC557729 PE=3 SV=2 CANONICAL=A0A8N7UV06-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 48, "start_aa": "Thr", "end_pos": 48, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr48", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:557729", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557729", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "catalytic activity", "id": "GO:0003824", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003824", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV06", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV06" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "67916", "name": "", "equation": "adenosine 5'-phosphoramidate + H2O = NH4(+) + AMP", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q5PNN8-1" ], "evidence": [ { "id": "67916", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/67916" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "Q5PNN8", "gene_name": "hint3", "activity": [ { "ec_number": "3.9.1.-", "activity": "", "evidence": [ { "id": "Q5PNN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q5PNN8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UV06", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV06" }, { "id": "PS51084", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51084" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HIT", "eco_id": "ECO_0000259", "start_pos": 179, "end_pos": 283, "start_aa": "Leu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 48 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, 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"count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UV15-1", "uniprot_ac": "A0A8N7UV15", "uniprot_id": "A0A8N7UV15_DANRE", "mass": { "chemical_mass": 52131.0, "monoisotopic_mass": 52131.0 }, "refseq": { "ac": "XP_693095", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693095" }, "gene_names": [ { "name": "LOC564674", "type": "recommended", "evidence": [ { "id": "A0A8N7UV15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV15" } ] }, { "name": "LOC564674", "type": "synonym", "evidence": [ { "id": "XP_693095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693095" } ] } ], "protein_names": [ { "name": "Protein brambleberry", "type": "recommended", "evidence": [ { "id": "A0A8N7UV15", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV15/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_693095", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693095" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_693095.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_693095", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693095" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV15", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV15" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC564674", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV15", "locus": {} } ], "crossref": [ { "id": "A0A8N7UV15", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UV15", "database": "AlphaFoldDB", "categories": [] }, { "id": "564674", "url": "https://www.ncbi.nlm.nih.gov/gene/564674", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040346", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040346", "database": "InterPro", 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"https://www.uniprot.org/uniprotkb/A0A8N7UV15-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MWTTALLAIVVCSVSSDKNLEDKGRLELQRVRELSQQPRYGACWSRALEKIQTSCKEFSDDVQSKIALSFTHCHLQRSGRSFPECTEDSDVKTCTQDMDPVAFNTYTEFFTHAHSICHYLQSERWQQRAQSTIHRLTESSAGVAEQLASTQRMAEDLVVAQSAALKSQESILRNGEELKSTLQDSTQGLRDVFAEMKHSAQEQQVAFAEIFNRVAFLQSFIMSETHTFSSLFYNALGFSASFLLTSVRRTAGARFFLFGLVALNIYLERLICKTVMENEEHGFQQMEKIAFFVGLLRKAMLLIGLLVLLFFALRFRNISRESLEILKELKETRSDLQQALQKAECLSASVDEWKRSRRKQWESRWEEQEDRLVILHPSSVVNEALSIFPKSQDNRHQETQSSSETLKRRQRHTSGSRLRTSSATVYSVLVEDTEPRYSLRSRKSLCGPEVSKVKS", "length": 455, "header": "tr|A0A8N7UV15-1|A0A8N7UV15_DANRE Isoform 1 of Protein brambleberry OS=Danio rerio OX=7955 GN=LOC564674 PE=4 SV=2 CANONICAL=A0A8N7UV15-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UV15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV15/entry#A0A8N7UV15-1", "sequence": { "sequence": "MWTTALLAIVVCSVSSDKNLEDKGRLELQRVRELSQQPRYGACWSRALEKIQTSCKEFSDDVQSKIALSFTHCHLQRSGRSFPECTEDSDVKTCTQDMDPVAFNTYTEFFTHAHSICHYLQSERWQQRAQSTIHRLTESSAGVAEQLASTQRMAEDLVVAQSAALKSQESILRNGEELKSTLQDSTQGLRDVFAEMKHSAQEQQVAFAEIFNRVAFLQSFIMSETHTFSSLFYNALGFSASFLLTSVRRTAGARFFLFGLVALNIYLERLICKTVMENEEHGFQQMEKIAFFVGLLRKAMLLIGLLVLLFFALRFRNISRESLEILKELKETRSDLQQALQKAECLSASVDEWKRSRRKQWESRWEEQEDRLVILHPSSVVNEALSIFPKSQDNRHQETQSSSETLKRRQRHTSGSRLRTSSATVYSVLVEDTEPRYSLRSRKSLCGPEVSKVKS", "length": 455, "header": "tr|A0A8N7UV15-1|A0A8N7UV15_DANRE Isoform 1 of Protein brambleberry OS=Danio rerio OX=7955 GN=LOC564674 PE=4 SV=2 CANONICAL=A0A8N7UV15-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:564674", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564674", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 317, "end_pos": 319, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 317, "end_pos": 319 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UV20-1", "uniprot_ac": "A0A8N7UV20", "uniprot_id": "A0A8N7UV20_DANRE", "mass": { "chemical_mass": 61828.0, "monoisotopic_mass": 61828.0 }, "refseq": { "ac": "XP_686669", "name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686669" }, "gene_names": [ { "name": "ftr91", "type": "recommended", "evidence": [ { "id": "A0A8N7UV20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV20" } ] }, { "name": "ftr91", "type": "synonym", "evidence": [ { "id": "XP_686669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686669" } ] } ], "protein_names": [ { "name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_686669", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686669" }, { "id": "A0A8N7UV20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV20/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_686669", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686669" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV20", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV20" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ftr91", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV20", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131125-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131125-31", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UV20", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UV20", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19769", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19769", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "558375", "url": "https://www.ncbi.nlm.nih.gov/gene/558375", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UV20", "url": "https://www.orthodb.org/?gene=A0A8N7UV20", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", 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"Protein" ] }, { "id": "A0AC58HDW8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HDW8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131125-31", "url": "https://zfin.org/ZDB-GENE-131125-31", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAESMLSQQKDQFSCSVCLDPLKQPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCREIFRQKPLLKKNTLIAEMMETLQKTALQTPAAAVDCDVCTTEKNRAVKSCLQCWASFCQTHLQLHYKSPAFMNHKLVEASRHICPNHKKPQDIYCQDDHQCICYLCMIDSHKGHRVVSVEAELINKKNKLKEMKLKCQTLIKERQRGWQELSIAMKLFKSSADEAVEKMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFEDVPSFTSHTHLSFKDLSFSAFREALEDACQQQTDAISREVSNIHVVKPPDLKTQNDFLQYFCQIHLDRNTAHKNLKVTEDNKKVSCSDKDQKYPDHPERFDGYCHVLCREGLTGRCYWEVECSGKYWAVAVCYRGISRKGVSDDCKLGFNKISWRLGYYLQNFSFIHGKAHVRLPPASRIGVYLDHKAGMLSFYSVSDTMTLLHRVQTTFTEPLYPAFYSGSGSSVKIIE", "length": 537, "header": "tr|A0A8N7UV20-1|A0A8N7UV20_DANRE Isoform 1 of E3 ubiquitin/ISG15 ligase TRIM25-like isoform X1 OS=Danio rerio OX=7955 GN=ftr91 PE=4 SV=1 CANONICAL=A0A8N7UV20-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UV20-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV20/entry#A0A8N7UV20-1", "sequence": { "sequence": "MAESMLSQQKDQFSCSVCLDPLKQPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCREIFRQKPLLKKNTLIAEMMETLQKTALQTPAAAVDCDVCTTEKNRAVKSCLQCWASFCQTHLQLHYKSPAFMNHKLVEASRHICPNHKKPQDIYCQDDHQCICYLCMIDSHKGHRVVSVEAELINKKNKLKEMKLKCQTLIKERQRGWQELSIAMKLFKSSADEAVEKMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFEDVPSFTSHTHLSFKDLSFSAFREALEDACQQQTDAISREVSNIHVVKPPDLKTQNDFLQYFCQIHLDRNTAHKNLKVTEDNKKVSCSDKDQKYPDHPERFDGYCHVLCREGLTGRCYWEVECSGKYWAVAVCYRGISRKGVSDDCKLGFNKISWRLGYYLQNFSFIHGKAHVRLPPASRIGVYLDHKAGMLSFYSVSDTMTLLHRVQTTFTEPLYPAFYSGSGSSVKIIE", "length": 537, "header": "tr|A0A8N7UV20-1|A0A8N7UV20_DANRE Isoform 1 of E3 ubiquitin/ISG15 ligase TRIM25-like isoform X1 OS=Danio rerio OX=7955 GN=ftr91 PE=4 SV=1 CANONICAL=A0A8N7UV20-1" }, "locus": {} }, { "isoform_ac": "A0AC58HDW8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV20/entry#A0AC58HDW8-1", "sequence": { "sequence": "MAESMLSQQKDQFSCSVCLDPLKQPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCREIFRQKPLLKKNTLIAEMMETLQKTALQTPAAAVDCDVCTTEKNRAVKSCLQCWASFCQTHLQLHYKSPAFMNHKLVEASRHICPNHKKPQDIYCQDDHQCICYLCMIDSHKGHRVVSVEAELINKKNKLKEMKLKCQTLIKERQRGWQELSIAMKLFKSSADEAVEKMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFEDVPSFTSHTHLSFKDLSFSAFREALEDACQQQTDAISREDFCQIHLDRNTAHKNLKVTEDNKKVSCSDKDQKYPDHPERFDGYCHVLCREGLTGRCYWEVECSGKYWAVAVCYRGISRKGVSDDCKLGFNKISWRLGYYLQNFSFIHGKAHVRLPPASRIGVYLDHKAGMLSFYSVSDTMTLLHRVQTTFTEPLYPAFYSGSGSSVKIIE", "length": 517, "header": "tr|A0AC58HDW8-1|A0AC58HDW8_DANRE Computationally mapped isoform of E3 ubiquitin/ISG15 ligase TRIM25-like isoform X2 OS=Danio rerio OX=7955 GN=ftr91 PE=4 SV=1 CANONICAL=A0A8N7UV20-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1REU8-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr65", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEFSVSVAQDQFSCAVCLDLLNDPVSIPCGHSYCMSCITDCWNKKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQEIHPGNQHQLTEATHRLKEMICPQHEKLLEIFCRTDHCCICYLCLVDQHKHHDTVSAAAERTELESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSITVSFPLDFDDIVKSVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTVNNWLVLSEGNTAVENKGSVQPYPDHPDRFDYWRQVLCRESVCGRSYWELEWSGARVFLSVSYKSIKRKGRGNECLFGRNAQSWSLSCSAESFSFRHNNKNTELPKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTNTLCPGFYVYKGSKVKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RFB3-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr14l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRSSTASQSRYGTQEKPRRSGRYSSSSSRSSSRDVLCDFCMIKKNKAVKSCLTCLTSFCEAHLQAHYEYPALMKHKLVAATGQLREKICGEHDKLLEVFCRSDQMCVCVLCIMEEHKKHDIVSAAAERTEKQKQLGAKLMTSQQKIEERMKKWQDLRQAVASLKHSSQSVLDENERIFAELLRALERRHGEVKEMIRAQEVLLLTNAERHLARLEEEITLLRKKHTDLEQLSQSDDHIHFLQSWQSLSAPSGYEDLSKVTLAPHHTFDNAKKAISDLKVQMEDISKEELNKISSAVNEVKILQTVDPAKREEFFEYSCQLSIDPLTAHPNLVLSDRNTVVQMSNEPRPYPDHPDRFDYWQQALCKPGLAGGRYYWELDWRGTEVDIAVTYKGIQRKGNDKPGSFGRNDKSWSLYCSESEYSFMHNSKSTAVSVPRSSRIGVYVDYESGTLAFYSVSDKMTLLYKVQTKFTEPLYPGIGVWGYGTTVRL", "length": 489 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RJY4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr03", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDSSKMAAESSVSFAQDQFNCSICLDLLKDPVAIPCGHSYCMSCISDYWDQDEWRGVYSCPQCRQTFTPRPALGKNTMLTEVVENIRKRKLQAGDVECDVCIGKAVKSCLVCLESYCQTHFEQHEEFHSRKRHKVTDANGRLQEMICPQHDRLLEMYCRTDQRCICMLCLMNEHKTHETVLPAEERAEKQKHFNEKLQQRIQEKQKQCEELRAAVESHKRSVQAAVEDTERIFTELIRSIERSRSKVTQLIRDQGKASVSGAEGRLEQLEQEINDLRRRNTELEQLSCTDNDIHFLQSFQSLSVPPASTDSSSISSRLSFNKFKMFVSRVKEELQNSLKDEKENISRIVRNISVLPTPEYERRKKFLQYYQQLTLDSNTAYKSLRLSEGNRVVTRMKKTSNHPDRFDGFAQLLCKESVRGRCYWEVERSGKGMYVSVSYKSIRRKGQGSECKFGCNDQSWSLYCSDTKCSFRHNNEESKLPVVSSSSRIGVYVDHSAGTLSFYSVSDTMSLIHRVHTTFTQPLYPGFGVSNESQVKLCDQA", "length": 542 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RKP5-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr76", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSESSSSECVDQFSCSVCLDLLKEPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCRESFSQRPLLKKNTLIAEMMETLQKTTLQTPAAAATAVDCDVCTTEKNRAVKSCLQCLASFCQTHLQLHYESPAFMKHKLVDASRHIQENICPSHGRPLEIYCQDDHQCICCLCIINSHKTHSVVSVDSEWINKKKELEKIAVERLKLIENREKGLWELSEAVKSFKSSADEAVEKMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIHKLLTTEDQIHCLKSCESVCVLPTFEEVPFSPHSHLSFKDLSISAFREALEDACRQQTDAISREVSNVHTVKPSEPKTYNDFLQYFYQPHLDPNTAHKNLILSEENRRISYSDTDQQYPDHPERFAAYCNVLCKEGLTGRCYWEVNCHGKIWAVAVCYKGISRKGNTDDNILGYNKQSWRLSRYQKNIFFVHNSEEVSIPVFHSSRIGVYLDHRAGILSFYSVSKTMTLIHKVQTTFTELLYPAFGLGECSIRIIKQKRFLKDQK", "length": 553 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" }, { "id": "MGI:102749", "url": "https://alliancegenome.org/gene/MGI:102749#orthology", "database": "AGR" }, { "id": "HGNC:12932", "url": "https://alliancegenome.org/gene/HGNC:12932#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RLP4-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25 isoform X1", "gene_name": "ftr02", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAQDQFNCSICLDLLKDPVAIPCGHSYCMCCISGYWDQDEQKGVYSCPQCRQTFTPRPALGKNTMLVEVVEKLRKRKLQAARPAQCYSESADVECDVCTGDKNKATKSCLMCLNSYCQNHLEQHETFFKIKRHNLMDATGRLQEMICPQHEKLLGIFCRTDKRCICYLCTMDEHKTHDTVSAAAERTDKQKYFEETLKKRIMENQKEREELRAALESHKRSVQATVEDTERIFTELICSIERTRSEVTQVIRDQEKAAVSGAERRLKKLEQEIDDLKRRNTELEQISNTDNHIHFLQNFQSFSVPPESTDTSIRSRLSFDDLVTFVSQVKEKLQQTVKQEQKNIFHIVRHINVMPSPQNKSRNDFLQYYKRFTLASNTAHESLKLSEGNRVVTRAKNALFSFPDIFEDLTQVLCNESVSGCCYWEVEWSGRGMCASVAYKSISRKGPGYDCRFGHNDQSWGLYFSDFSCSFWHNNIHTKLPGVSSSSRIGVYVDHSTGTLSFYSVSGRMRLIHRVYTTFTQPLYPGFGVCHDSQLKLCD", "length": 546 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RLR7-1", "protein_name": "Tripartite motif-containing protein 16 isoform X1", "gene_name": "ftr33", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSKMAESSVSLAHREFSCSVCLDLLKDPVAIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQQLNPGNRHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISRRVSSISIIPAPEPQTREQFLQYSQQFTLDPNTAHTYLVLSEGNTAVENKGSVQPYPDHPDRFDCWRQVLCRESVCGRSYWELEWSGVDVLISVSYKSISRKGSGNECLFGLNDQSWSLCCSADSFSFRHNNINTDLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFWVCSRLKLCDLTV", "length": 561 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RN91-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr36", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFCPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQELNPGNQHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTELESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTANNRLILSEGNTVVDCKGSVQPYPDHPDRFDGWFQVLCKESVCRRSYWELEWSGNGVEIAVSYKSISRKGSILECRFGLNDQSWSLFCSVHSFSFWHNNKQTQLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHALYPGLCLYSRVKLCDLTV", "length": 556 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2B8U3-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr57", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEVRFSLEEFMCPVCLDLLKDPVTIPCGHSYCKTCITGCWDQEDDKRVYSCSQCREAFNPRPALAKNTILAEMVEKLKTKPPADCYAGAGDVQCDVCTGIKYKAIKSCLVCQESYCRTHFDRHEEFHSRKPHKVIDATERLQDMICRKHEKELEMYCITDQMCICLMCKEYEHKNHETMSTAAQRTEKQKELKETQMKLQQRVQQRQKDLQQLREAVESQKRCAQTAVEDTDRIFTEIIRLIERRRSELTQMIRDQQKTAVSEAEGLMKRLEKEIDHLRRRGAELEQLSHTQDHIHFLQSFQSLSAPPESTDVSFNPLLSFDDLKESVQQLKVKLEDFCKEEIRKTSDKGTPILNDPFKDTFANIVPKTTRDFLKYYSRFTLDLNTVNKYLCLSSNMITYTNTPQPYPDHPDRFDQLCQVLCRESVSGRCYWEIKWSGYGVCISVSYKGIRRKGQGKDCIFGGNDQSWCLFCYPGDYSFIHNDLKTVLPVQSISSRVGVYVDHSAGILSFYSVSNTMTLIHKVQTTFTQPLYPGFNVNGYKSSVILC", "length": 548 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAS0-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr26", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSTSVVEDQFSCSICKDLLREPVTIPCGHSYCMICITDCWSQDEQRRVYSCPQCRQTFTPRPALNKNVVMAEMVENLKKTGLKSRANYAEAGDVKCDVCAGRKRKAVKSCLLCLNSYCETHFECHEVFHSSKRHKVTDATGRIQEMICSQHDRLLEVYCRTDQKCVCLMCVMDEHKNHDTVSAEAERAEKQIQVGETQTQLQNRIQEKQSKLQQLRESVEIHKSSAQTAVDDCERIFTEIIRCIKRRRLKVTQMIRDREKTEVSRAEGLLKKVEQEIEDLKRRNTELEQLSHTDDHIHFLQSLQPLIIPAESTDSMTVSSLPSYEDVGKSVSELRKKLDDFCKEQIKLISASVSCRTQILPTTKPKTREDFLKYFHQFTLDSQSVHNNLSLSDENRVATFTASMHAYPDHPDRFDTWPQVLCRENVCGRCYWEVEWSGNHGVAIAVSYKSISRKGQGTECKFGYNDQSWRLFCSASGYIFSHNNRKRDLPVVSKIGVYVDQRAGVLSFFRVSDTKMSLIHRVQTTFTQPLYPGFGLNRDSSVKLSSMI", "length": 551 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAU1-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr34", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNQHKVTEATHKLQEMICPQHEKPLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTEQESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFFISSQLSFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISIIPAPEAQTHEQFLQYSQQFTLDPNTAHNRLVLSEGNTAVENNWSVQPYPDHPDRFDGYSQVLCRESVCGRSYWELEWSGNGVEISVSYKSISRKGSGNECLFGRNDQSWSLCCSPLSLSFYHNNINTKLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFYVNYSSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAX9-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr35", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHNYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNRHKVTEATHKLQEMICPQHEKPLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTEQESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEIEMISSRVSSISIITAPEPQTREQFLQYSQQFTLDPNTAHKYLVLSEGNTAVEDKDSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGDGVYLSVSYKSISRKGSGNECGFGHNDQSWSLCCSDYSFSFRHNNIKTKLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLMHTLHTTFTHTLYPGFCVYYSSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQJ4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr95", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCAVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHQGNRHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTAYNRLVLSEGNTAVENKRSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGEDVEISVSYKSISRKGLGNECVFGFNDQSWSLSCSAHSFIFYHNNIKTDLRKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFRVYVCSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B808-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr29", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAHHEFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFCPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHQGNRHKVTEATHKLQEMICPQHEKLLEIFCRTDHCCICYLCLVDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSPLVFDDIAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTAYNRLVLSEGNTAVENKRSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGEDVEISVSYKSISRKGSGNECVFGFNDQSWSLSCSAHSFIFYHNNIKTDLRKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFRVYVCSRLKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YUU8-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSVAHREFSCAVCLDLLKDPVSTACGHNYCMSCITNCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEMVEKLRKSKLQAAGPAQSPAASGDVECDVCSGAKNRAVKSCLVCLNSYCHTHFQLHQQLNPGNQHKVTEATHRLKKLICPQHEKPLEIFCRTDHCCICYLCTMDQHKNHNTVSAVAERTEQQRRLKNIQSSFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLSFNKVTESVSRLRDKLQQFCTEEMKTISSRVSSISIIPAPEPQTREQFLQYSQQFTLDPNTAHTYLVLSEGNTAVENKGSVQPYPDHPDRFDCWHQVLCRESVCGRSYWELEWSGVDVLISVSYKSISRKGSGNECLFGLNDQSWSLCCSADSFSFYHNNIKTDLPKPSVSSSRRGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFCVYYSSRLKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YW98-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEAGISWSQNQFSCSICLDLLKGPVTIPCGHSYCMRCISGYWDQDKQRGVYICPQCRQTFTPRPALGKNTMLAEVVEQLKKTKLQAARPAHCYSESADVECDVCTGDKNKAVKSCLVCLNSYCQNHLEQHESFFRGKRHNLMDATGRLQEMICPQHDKLLEVFCRTDQCCICLLCVDEHKNHEIVSATAERTDKQRQLEETQSKHNQRIQRKQEECVELRVAIESQKCSAQAAVEDTERIFTDLIRSIERRRSEVTQLIRDQEKAQVSAAEGRLERLKQEIDDLRRRDAELEQLSHTDHHIHFLQSFQSLSTPPGSTDSSSITVSSSLSFDDVGKSVSRLREKLEDFCREEIEKISVRGITSIQKPELKTREDFLQYYRPLTLDPNTVNNCLVLSEGNRVFEHTSTNQQYPDHPDRFDCFLQVLCRENVYGRCYWEVEWSGDVEILVAYKSISRKGLGDECGFGRNDQSWGLSCSRSRCSFCHNKKQTKLPVMSNSSRIGVYVDHSAGTLSFYSISNTMSLIHRVHTTFTQPLYPGFGIDSLYSLFSETKQKIKLSDLKI", "length": 561 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1N9-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25 isoform X1", "gene_name": "ftr73", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCLHVADCFEASAKMSESSSSEYVDQFSCPVCLDLLKEPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCRESFSQRPLLKKNTLIAEMMETLQKTALQTPAAAAVDCDVCTTEKNRAVKSCLQCLASFCQTHLQLHYESPAFMKHKLVDASRHIQENICPSHGRPLEIYCQDDHQCICCMCTDNHKGHSVVSVDSEWTSKKEELEEMKLKCLKLIKDREKGQQDLSKATKNLKSSADEAVERMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFKDVPSFTSHTHLSFKDLSISAFREALEDACQQQTDAISREVSNVHVVQTPQPKSEHDFLQYYCKLQMDSSTAHRELKLSEEKRKVSFSDEVQPYPDHPQRFDWFHYILCREGLTGRCYWEVECSGDIWGVAVCYRGIRRKGNSDDCKLGFNKVSWRLNRLQQNITYIRNKVQVRIKAGCFSRIGVYLDHRAGILSFYSVSDTNTLLYKVQTTFTEPLYPAFIIGQGSSVRIFDKRTAQMEELT", "length": 567 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" }, { "id": "MGI:102749", "url": "https://alliancegenome.org/gene/MGI:102749#orthology", "database": "AGR" }, { "id": "HGNC:12932", "url": "https://alliancegenome.org/gene/HGNC:12932#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PAX6-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEGRFSVDQNKFDCPICLDLLKEPVTIPCGHSYCMNCITDCWSQDEQRRVYSCPQCRQTFTPRPALNKNVVMAEMVENLKVTKVKTTDPAPSYAGPGDVECDVCTGIKYKAIKSCLLCLESYCQTHFERHEAFRTGKRHKITDASGRIQEMICLKHDKLLEVYCRTDQKCICLLCTMDEHKNHDTVSSSSERTEKQKHLEDTQRNLQQKIQEREKKIQVLKESLKTHKSSAQTAVEDSERTFTELIQSIERRRSEVTQMIRDREKTEVSLTEGLLKKLEQEIEDMKRRNTELEQLLHTDDHIHFLQRFQSLSKPLESTDLSSTAVSSGFRYEDVSKSVSQLKIKLEQICTEDIENIHGQARKMIFSALLSTSHTEPTTRKDFQQYFQQLSLDQNTAHQQICLTEDNTVATWTDRVQQYPDHPDRFDKFFGVLCRESVSGRCYWEVEWSGNERLYGVGVAVSYKTINRKGDMTTSGFGFNDQSWRLFSFKSRYTFLHDSKQTELSVVSRSSRIGVYVDHRAGILSFFSVSDTTMSLIHRVQTTFTQPLYPGFWINKGSRVKICHI", "length": 565 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PJ13-1", "protein_name": "Tripartite motif-containing protein 16 isoform X1", "gene_name": "ftr11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVCLAQEQFSCSICLDLLKDPVAIPCGHSYCMSCISDCWDQDERKGVYSCPQCRQTFTPRPALGKNTMLTEVMENIRKRKLQAGDVECDVCTGRKFKAVKSCLVCLESYCQTHFQHHEEFHSRKRHKVTDATGRLQEMICPQHEKLLEIFCRTDQCCICYLCTMDKHKNHDTVSAAAEWTDKKIQLAEMQKTTHQRMVERQKEREELRAAVESHKRSAQAAVEDTESIFTELIFSFERSCSEVTQLITDQQKAAEGRAEERLKQLEQEINDLRRRNTELEQLSHTDHHIHFLKSFQSLSSPPGSTDSSSITVSSRISFDDVGKLSHLRKKLEQFCREEIEKISSKVRDINIISISAEPKTRQEFLQYSRQLTFDPNTVNTSLVLSKKNRVIEYTDKVQQYPDHPDRFDCWPQVLCRESECGRFYWEVEWNGYIEISVSYKSISRKGRGNECVFGCNDQSWSLFCSRSRFSFRHNKQQTKLPVLSISSRIGVYVDHSAGTLSFYNVSDTMSLIYRVHTTFTQPLYPGFWVFAGSILFTTDTL", "length": 545 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PRK9-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr41", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEVRISVDQIEFMCPVCLDLLKDPVTLHCGHSYCKSCITDFWDQEYEKRIYSCPQCRQSFTPRPALAKNTMLAEVVEKLKKTKPPADCCAGAGDVQCDACTGRKYKAVKSCLQCQESYCQTHFERHEEFHSRKPHKVIDATGQLRDMICQKHGKELEIYCITDQQCICELCKEYEHKNHATVSTAEQMTEKQQELKERQVKLQQREKALRKLKNAVESQKRSAQTAVEDTEKIFTELIHSIQKKGTELTQVISSAEKTAVSQAEEHMEYLEQEIEDLRRRNAELERLSQTQEHVNFLQRFQSLPAPLESTDGYFSSFLCFDAMKESVHELKSKLENLCKEEIKMILDRVTSFVPKTRNDFLQYSIKLTLDLHTAHKCLSKKRKVVTCTKKEQPYPDHPDRFHDWPQVLCTERVRGRRYWEVEWSGDKGVCISASYKSISRTGTGNECAFGGNDHSWSLFCSPLRYLFWHNNIQSDLTVKPNSHKIGVYVNVGAGTLSFYNVSDEMSLIHTFQTTFTQPLFPGFTVGFGSSVKLKHR", "length": 537 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6I4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr94", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEARFSQDEFLCPVCLELLKDPVSLHCGHNYCKGCISGFWDQEDEKRVYSCPQCRQTFSQRPALAKNTMLAEVVEKLKKTKPPADCKAGAGDVQCDVCTGTKYKAIKSCLQCQESYCQTHFENHEEFHFRKSHKVIDATGQLQDMICQKHKKELEIYCITDQQCICELCKEFEHTTHETLSVAEQRKEKQKELKETQVKLQESLQQRQQELQQLREAVESHKRSAQTAVKDTERIFTELICSIEKRCSELTQIIRDQEKTAVSRAEGHMEWLEQEVENLRRRNAELEQLSHKKDHVQFLKSFQSFSAPPESTDVLSSSLLCFDGLSESVSQLKDKLEDFCKKELKKISDRVTKTSPKTRNDFLQYSHQFTLDLNTMNDHLRLSESNRVITGAETAQPTFDHPDKFNGWPQVLCRESVRGRCYWEIEWSGDVGVILSVSYKSISRKGFGNECAFGGNDKSWSLACFPTRYSFWHNSKRTDLSVKPISRMIGVYVDESAGILSFYGISNTISLIHTVKTTFTQPLYPGFTVDPRSSVKLC", "length": 539 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TBM3-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr37", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSVAHHEFSCAVCLDLLKDPVSTACGHNYCMSCITNCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNQHKVTEATHKLKKLICPQHEKPLEIFCRTDQLCICYLCTMDQHKNHNTVSAVAERTEQQRRLKNIQSSFQQRLQERQKELEKLKKAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSPLVFDDIAESVSHLREDLEHFGKKEIKLISRRVSSISRIPAPVPKTREQFLQYSQQFTLDPNTVNNWLVLSERNTVVKYKGSVQRYPDHPDRFNCWYQVLCRESVCGRSYWELEWSGVDVYLSVSYKSISRKGSGNECLFGYNDHSWSLWCSADSFIFYHNNKQTKLPKPSVSSTRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHALYPGFCVHYSSRVKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UV86-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr38", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAHCKFSCSECLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQELNPGNQHKVIEATHRLKEMICQQHKKLLEIFCRTDHCCICSLCVLDGHKNHDTVSAAAQRTKKQCRLKKTQSRFQQRLQERQKELEELREAVESHKHSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSFQSLSVPPGSTDSSSFFISSQLSFNKVTESVSRLSDKLQQFCTEEMKTISDKVRFISIIPAPEPQTREQFLQYSQQFTLDPNTVNKKLVLSEGNTAVEINGSDQPYPDHPDRFDGFSQVLCKESVCGRSYWELECSSASVYLSVSYKSISRKGSGNECRFGNNDQSWSLFCSDNSFSFWHNNIKTDLRKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFYVYLAKVKICDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UVE5-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAECSISVAQDQFSCSICLDLLKDPVAIPCGHSYCMSCISDCWDQDEQRGVYSCPQCRQTFTPRPALGKNTMLAEVVGKLKKTKLQAARPAQCYSESADVECDVCTGDKNKAVKSCLMCLNSYCQNHLEQHASFFRSKKHNLMDATGRLQEMICPQHDKLLEVFCRTDQCCICYLCTMDGHKNHNTVSAAAERTDKHRQLEETQSKLHQRIQRKQVEFEELRAAVESHKCSAQAAVEDTERIFTDLIRSIERSRSEVTQLIRDQEKAAVSEAEGRLERLEQEIDDLRRRDAELEQLSHTDHHIHFLQSFQSLSTPPGSTDSSSITVSSSLSFDDVGKSVSRLREKLEHFCREEIEKITWRMRDYKGTTPTPEPKTHQEFLQYTCWLFLDLNTMNKNLVLSKGNRVIELSSTVQQYPDHPDRFDCWHQVLCRESVCGRCYWEVEWSGSVGISVAYKSIGWKGQGTEFGYSNQSWCLFCSGSICTFVHKSKHTVLPLVSSSSRIGVYVDHSAGTLSFYSVSDTMSLIHRVHTTFTQPLYPGFELVSYNPCGSKLKLCEL", "length": 557 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58GXY0-1", "protein_name": "FinTRIM family, member 23 isoform X1", "gene_name": "ftr23", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGFSETGKCSPTLLSEMAESSISVAEDQFSCSVCLDLLKEPVTIPCGHSYCMNCITDCWNQDEQRRVYSCPQCRQTFTPRPALNKNVVMVEMVEKLKTGSRNAASYAGPGDVECDVCTGRKRKAVKSCLMCLSSYCQTHLEQHDSFFKDKRHHLINATGRLRQMICSKHDRLLEVYCHTDQKCICLLCMMDEHTGHQTVSIKTERAEKQKQLLDLQKNFQKTIQEREEEVWDLKHAVKTHKHSAQTAVEESERIFTRLFHFIERRQSEVSQMIRDRKKTEVSRAEGLLKKLEEEIEDLKRRNTELEQLSHTDDHIHFLQSFHSLSAPPESPESSDVTSLLFYDDVGETLSVLKEKLEDACKEATENMSVLETPYMEIVSTSELINRDKFLQYFHHLTLDSNTAHKYLRLSEGNRVATFIGADQSYPAHPDRFHDFSQVLCRESVCGRCYWEVEWSGEAGVGISVSYKSIRRKGEGFDCVFGFNDQSWRLSCSNSRYTLRHKQLSTKLRVPSGSNRIGVYVDHKAGILSFFNISDTMSLIHRVQTTFTQPLYPGFGINFGSTVKLKSAENL", "length": 570 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58I1B9-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X2", "gene_name": "ftr30", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTHTGSVRAERNRKFTQIPCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKQQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQQLNPGNQHKVIEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEAQTREQFLQYSQQFTLDPNTVNNCLVLSEGNTAVDYKDSVQPYPDHPDRFDCSYQVFCRESVCGRSYWELEWSGVVYLSVSYKSISRKGRNIECGFGNNDQSWSLECSPYSFSFWHNKIKTALPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFGVYSSRLKLCDLTV", "length": 562 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ACD6B7A1-1", "protein_name": "LOW QUALITY PROTEIN: tripartite motif-containing protein 16", "gene_name": "ftr42", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAETRFSQDEFLCPVCLDLLKDPVAIHCGHSYCKSCITDFWNMEDEKGIYSCPQCRQTFSPRPALAKNTMLAEVVDKLKKTTPPADCYAGAEDVQCDACTGTKYKAIKSCLQCLESYCQTHFERHEEFHSRKPHKVIDATGRLQDMICPKHEKELEVYCITDQQCICELCKEYEHKNHKTVSAAAQRTEKQKELKETLVKLQERLQQRQKDLQQLRAAVESHKQSAQTAVEDTDRIFTELIYSIEKRRSELTQMIRDQEKTTRSRAERHMEQLEQEIEDLRRRNTELEQLSHTHHHIHFLQSFQSLSAPPESTDVSFSSLLCFDGLRESVSQLKVKLEDFCIEEIEKFTERVTKTVPKTRNDFLQYSHKLTLDLNTAHKLLHLSERNRIIICTETEQPYPDHPDRFDSWRQVLCRESVRGRCYWEIEWSGIKGVCISVSYKSISRKGFGNECVFGGNDQSWGLFCSTSRYSLWHNKKRSDLPLKPISRRIGVYVDVGAGTLSFYSIFDTMSLIHTVQTTFTQPIYPGFTVDPRSSVKLC", "length": 539 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A9N5-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "Trim25", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAELFPLAEELSCSICLEPFKEPVTTPCGHNFCRSCLNETWVVQGPPYRCPQCRTVYQVRPQLHKNTVLCAVVEQFLQAEQARTPVDDWIPPTRSAASSSDTQVSCDHCLKEVAVKTCLVCMASFCQEHLRPHIDSPAFQDHPLQPPVRDLLRRKCSRHNRLREMFCPEHGECICHICLVEHKTCSPTILSQASADLENKLRQKLTIMYSHINGASKALEDVKSKQQNVQESMKRKMLQLRQEYLEMKAVIDAAETSSTHKLKEEEKRVYGKLDTIYQVLLKKKNEMQNLKAEVELILAKGDEFEFLEKAAKLQEVSTKPVYIPKIDLDHDLIKGVYQGALDLKSELKLSLKQLQEKKAEEPCNSGNVGDHAQSTSKPTRPAKKTAPDKKTKKTPGAAGAAGAAGAAGAAGPTSYSSSSNKLPTFGAPGQATIPDATLKPNAPQPNSAAVKAKVLENFLTMSRTELLEYFVKVVFDYNTAHNKVALADNYTTASVADGLQHYRSHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGVCYGSMDRQGPESRLGRNPSSWCVEWFNNKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVTEKVYLMYKFKVDFTEALYPAFWVFSAGTTLSICSK", "length": 643 }, "evidence": [ { "id": "MGI:102749", "url": "https://alliancegenome.org/gene/MGI:102749#orthology", "database": "AGR" }, { "id": "HGNC:12932", "url": "https://alliancegenome.org/gene/HGNC:12932#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LMT9-1", "protein_name": "Tripartite motif protein 80", "gene_name": "Trim80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSAKLGSFLRKGHLDRETMKQQPQRTVRRRRSPVHRAAKYLAVIDMQKISRPTQDKSPSELSTQSSRTSLQLLMSSNSSQHLLEDQVLCPICLDVFRNPVTTACGHNFCMTCLQSFWDHQADTGETYYCPQCREAFPSRPRLCKNVILGEMVACFTLAKSQTSGPLWGLAGPTDVPCDFCSPQKLKATKSCLQCMASLCEKHLHSHFEDPLFQEHQLLDPVWDLKNRLCRKHRKLRQMYCRTEGSCVCGACLLEEHQNHDTTPLEDERARKEVEVRKIQANVENQMLIIASDSQKHQGRVSFLSKLIQTMREEVNTCFSEILHEVKQLQMKVLDFVENEETVALGMLGNSMQQSHSRLLKLEGDSVWLHGLLANKSDEQFLQEFPTLKHFPACVEPLLGTNCEETQSFLQLPETLAQLRIRLMDIGLNFINQLLLKGIRMNSYEVLPATVDRKTLLQNYCNLNFDSSMASEELFLFKETHSVLNLGILLEPSTTSPLPGFKQWPQVLCCPGLSEGCHYWETEVSDSWMCLGVTYRRNPSMSGRHRRNIVYLLGRNPYSWCLEWDSLKFSVWHNNTQTVLHGSYHHTLGVALDFRAGCLSFYGVAGDVSLLYRFLTSFLEPLYPAVMVSSGASLTLKQYPEA", "length": 642 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131125-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131125-31#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14258-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "TRIM25", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAELCPLAEELSCSICLEPFKEPVTTPCGHNFCGSCLNETWAVQGSPYLCPQCRAVYQARPQLHKNTVLCNVVEQFLQADLAREPPADVWTPPARASAPSPNAQVACDHCLKEAAVKTCLVCMASFCQEHLQPHFDSPAFQDHPLQPPVRDLLRRKCSQHNRLREFFCPEHSECICHICLVEHKTCSPASLSQASADLEATLRHKLTVMYSQINGASRALDDVRNRQQDVRMTANRKVEQLQQEYTEMKALLDASETTSTRKIKEEEKRVNSKFDTIYQILLKKKSEIQTLKEEIEQSLTKRDEFEFLEKASKLRGISTKPVYIPEVELNHKLIKGIHQSTIDLKNELKQCIGRLQEPTPSSGDPGEHDPASTHKSTRPVKKVSKEEKKSKKPPPVPALPSKLPTFGAPEQLVDLKQAGLEAAAKATSSHPNSTSLKAKVLETFLAKSRPELLEYYIKVILDYNTAHNKVALSECYTVASVAEMPQNYRPHPQRFTYCSQVLGLHCYKKGIHYWEVELQKNNFCGVGICYGSMNRQGPESRLGRNSASWCVEWFNTKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVADKVHLMYKFRVDFTEALYPAFWVFSAGATLSICSPK", "length": 630 }, "evidence": [ { "id": "MGI:102749", "url": "https://alliancegenome.org/gene/MGI:102749#orthology", "database": "AGR" }, { "id": "HGNC:12932", "url": "https://alliancegenome.org/gene/HGNC:12932#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131125-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131125-31#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q61510-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "Trim25", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELNPLAEELSCSVCLELFKEPVTTPCGHNFCMSCLDETWVVQGPPYRCPQCRKVYQVRPQLQKNTVMCAVVEQFLQAEQARTPVDDWTPPARFSASSAATQVACDHCLTEIAVKTCLVCMASFCQEHLRPHFDSPAFQDHPLQSPIRDLLRRKCTQHNRLRELFCPEHGECICHICLVEHKTCSPTTLSQASADLEYKLRNKLTIMHSHINGATKALEDVRSKQQCVQDSMKRKMEQLRQEYMEMKAVIDAAETSSLRKLKEEEKRVYGKFDTIYQVLVKKKSEMQKLKAEVELIMDKGDEFEFLEKAAKLQGESTKPVYIPKIDLDHDLIMGIYQGAADLKSELKHSIKKLQKKSEEHNGSGNKGDQTQSTFKPVQPSKKTIQEKKTKKTPVAPGPPSHFSPNKLPTFGAPGQSLDSKATSPDAAPKASAAQPDSVGVKAKVLENFLTKSRTELLEYFVKVIFDYNTAHNKVSLSNKYTTASVSDGLQHYRSHPQRFTYCSQVLGLHCYKNGIHYWEVELQKNNFCGVGICYGSMERQGPESRLGRNPNSWCVEWFNNKISAWHNNVEKTLPSTKATRVGVLLNCDHGFVIFFAVTEKVHLMYKFKVDFTEALYPAFWVFSAGTTLSICSK", "length": 634 }, "evidence": [ { "id": "MGI:102749", "url": "https://alliancegenome.org/gene/MGI:102749#orthology", "database": "AGR" }, { "id": "HGNC:12932", "url": "https://alliancegenome.org/gene/HGNC:12932#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131125-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131125-31#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV20", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV20" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV20", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV20" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV20", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV20" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 469, "end_pos": 471, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UV20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV20" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 137, "end_pos": 177, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UV20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV20" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 351, "end_pos": 537, "start_aa": "His", "end_aa": "Glu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UV20", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV20" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 58, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 469, "end_pos": 471 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UV68-1", "uniprot_ac": "A0A8N7UV68", "uniprot_id": "A0A8N7UV68_DANRE", "mass": { "chemical_mass": 64127.0, "monoisotopic_mass": 64127.0 }, "refseq": { "ac": "XP_689574", "name": "mucin-5AC", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689574" }, "gene_names": [ { "name": "si:dkey-205h13.2", "type": "recommended", "evidence": [ { "id": "A0A8N7UV68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV68" } ] }, { "name": "si:dkey-205h13.2", "type": "synonym", "evidence": [ { "id": "XP_689574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689574" } ] } ], "protein_names": [ { "name": "Mucin-5AC", "type": "synonym", "evidence": [ { "id": "A0A8N7UV68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV68/entry#names_and_taxonomy" } ] }, { "name": "mucin-5AC", "type": "synonym", "evidence": [ { "id": "XP_689574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689574" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_689574.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_689574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689574" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV68", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV68" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-205h13.2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV68", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080225-18", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080225-18", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UV68", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UV68", "database": "AlphaFoldDB", "categories": [] }, { "id": "561081", "url": "https://www.ncbi.nlm.nih.gov/gene/561081", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR025155", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025155", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561081", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561081", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UV68", "url": "https://www.orthodb.org/?gene=A0A8N7UV68", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15031", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15031", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15031:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15031:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13330", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13330", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_689574", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689574", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UV68", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV68", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UV68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV68-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080225-18", "url": "https://zfin.org/ZDB-GENE-080225-18", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNTKVFATLVVVVTSTLFSLSTQSCITQWFDNDDPTGQGDYELLSDLLTAYSGEICPNPVGIEVRTVSGILASQTGNIFQVNNPSSGFACVNANQAGGVCADYKVRFTCPEAWCASCRTPWFDRDNPGGLGDYETLPLTLSTYPLQVCAQPIAIEVETISGTPTLPTGNNFQEYDPKLGFSCVNAQQNGGCQDYKVRFTCPVIFCQPQCVTRWFDSDNPNTNGSDSELLSVLQSANAGYICSNPLGIEAQTISGQPASQTGNVFQSYNPTVGFSCVNANQASGMCADYKVRFTCPEQWCSSCRTPWFDRDDSSGLGDYETLPLIQIAYPLQVCAQPIAIEVTTLSGTPALPTSFPDYDALLGFKCVNGACQDYRVRFTCPKTFCGGQCVTRWFDSDDPTTKGGDSELLTNLLSAYSGSICPNPLGIEAQTVSGQSASQTGNVFQVYDPTNGFSCLNANQGGAICADYKVRFTCPEEWCSKCMTPWFDRDNPGGMGDYEPLSLTPTAFPQQVCAQPIAIEVSTITGTPVLPTGNHFQTFDPLLGFECVNDFQNGWTCLDYKVRYKCFCKIVGPTIESRPFELTNLTDFLNVG", "length": 591, "header": "tr|A0A8N7UV68-1|A0A8N7UV68_DANRE Isoform 1 of Mucin-5AC OS=Danio rerio OX=7955 GN=si:dkey-205h13.2 PE=4 SV=1 CANONICAL=A0A8N7UV68-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UV68-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV68/entry#A0A8N7UV68-1", "sequence": { "sequence": "MNTKVFATLVVVVTSTLFSLSTQSCITQWFDNDDPTGQGDYELLSDLLTAYSGEICPNPVGIEVRTVSGILASQTGNIFQVNNPSSGFACVNANQAGGVCADYKVRFTCPEAWCASCRTPWFDRDNPGGLGDYETLPLTLSTYPLQVCAQPIAIEVETISGTPTLPTGNNFQEYDPKLGFSCVNAQQNGGCQDYKVRFTCPVIFCQPQCVTRWFDSDNPNTNGSDSELLSVLQSANAGYICSNPLGIEAQTISGQPASQTGNVFQSYNPTVGFSCVNANQASGMCADYKVRFTCPEQWCSSCRTPWFDRDDSSGLGDYETLPLIQIAYPLQVCAQPIAIEVTTLSGTPALPTSFPDYDALLGFKCVNGACQDYRVRFTCPKTFCGGQCVTRWFDSDDPTTKGGDSELLTNLLSAYSGSICPNPLGIEAQTVSGQSASQTGNVFQVYDPTNGFSCLNANQGGAICADYKVRFTCPEEWCSKCMTPWFDRDNPGGMGDYEPLSLTPTAFPQQVCAQPIAIEVSTITGTPVLPTGNHFQTFDPLLGFECVNDFQNGWTCLDYKVRYKCFCKIVGPTIESRPFELTNLTDFLNVG", "length": 591, "header": "tr|A0A8N7UV68-1|A0A8N7UV68_DANRE Isoform 1 of Mucin-5AC OS=Danio rerio OX=7955 GN=si:dkey-205h13.2 PE=4 SV=1 CANONICAL=A0A8N7UV68-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561081", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561081", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV68", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV68" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 583, "end_pos": 585, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UV68", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV68" }, { "id": "PF13330", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13330" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WxxW", "eco_id": "ECO_0000259", "start_pos": 27, "end_pos": 109, "start_aa": "Thr", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 222, "end_pos": 224 }, { "start_pos": 583, "end_pos": 585 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UV72-1", "uniprot_ac": "A0A8N7UV72", "uniprot_id": "A0A8N7UV72_DANRE", "mass": { "chemical_mass": 51783.0, "monoisotopic_mass": 51783.0 }, "refseq": { "ac": "XP_690007", "name": "E3 ubiquitin-protein ligase TRIM35", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690007" }, "gene_names": [ { "name": "trim35-25", "type": "recommended", "evidence": [ { "id": "A0A8N7UV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72" } ] }, { "name": "trim35-25", "type": "synonym", "evidence": [ { "id": "XP_690007", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690007" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase TRIM35", "type": "synonym", "evidence": [ { "id": "XP_690007", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690007" }, { "id": "A0A8N7UV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_690007.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_690007", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690007" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV72", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "trim35-25", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UV72", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UV72", "database": "AlphaFoldDB", "categories": [] }, { "id": "561511", "url": "https://www.ncbi.nlm.nih.gov/gene/561511", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027370", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027370", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050143", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050143", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561511", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561511", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UV72", "url": "https://www.orthodb.org/?gene=A0A8N7UV72", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24103", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24103", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13445", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13445", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_690007", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690007", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UV72", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UV72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-484", "url": "https://zfin.org/ZDB-GENE-060503-484", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASLNVSEDLSCPVCCEIFKNPVVLSCSHSVCKECLQQYWRTKTTQECPVCRRRSSKGEPPVNLALKNLCELFLKERNERCSSASEEICSLHSEKLKLFCLEDKQPVCVMCVTLQQHDNHKFRPISEVASSYKEELNTALKSLQVKLKRNEERKAEFEKTVQHIKSQADHTERQVKHEFEKLHQFLRDEEEATITALREEEEQKKQMMKEKLEEMNTHISALSHTIKDTEEMLKAKDVCFLKEFPVSMERVQISQPDPQTPSGALIHVAGYLGNLTYRVWKKMQDIVHYTPVILDPNTAHPGLILSDDLTTLRNRRNTQPSPDNPERFDQMYCVLGSEGFISGKHCWDVEVKESLYWNFGVTTASNQRKGFFSTGVWSVRCELSFGSGFIVKQSLERVRVDLDCDRGTVSFSDPLKNTHLHTFTTTFTESVFPYFYFNDIVNCLKILPC", "length": 449, "header": "tr|A0A8N7UV72-1|A0A8N7UV72_DANRE Isoform 1 of E3 ubiquitin-protein ligase TRIM35 OS=Danio rerio OX=7955 GN=trim35-25 PE=4 SV=1 CANONICAL=A0A8N7UV72-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UV72-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72/entry#A0A8N7UV72-1", "sequence": { "sequence": "MASLNVSEDLSCPVCCEIFKNPVVLSCSHSVCKECLQQYWRTKTTQECPVCRRRSSKGEPPVNLALKNLCELFLKERNERCSSASEEICSLHSEKLKLFCLEDKQPVCVMCVTLQQHDNHKFRPISEVASSYKEELNTALKSLQVKLKRNEERKAEFEKTVQHIKSQADHTERQVKHEFEKLHQFLRDEEEATITALREEEEQKKQMMKEKLEEMNTHISALSHTIKDTEEMLKAKDVCFLKEFPVSMERVQISQPDPQTPSGALIHVAGYLGNLTYRVWKKMQDIVHYTPVILDPNTAHPGLILSDDLTTLRNRRNTQPSPDNPERFDQMYCVLGSEGFISGKHCWDVEVKESLYWNFGVTTASNQRKGFFSTGVWSVRCELSFGSGFIVKQSLERVRVDLDCDRGTVSFSDPLKNTHLHTFTTTFTESVFPYFYFNDIVNCLKILPC", "length": 449, "header": "tr|A0A8N7UV72-1|A0A8N7UV72_DANRE Isoform 1 of E3 ubiquitin-protein ligase TRIM35 OS=Danio rerio OX=7955 GN=trim35-25 PE=4 SV=1 CANONICAL=A0A8N7UV72-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561511", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561511", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3B3IT33-1", "protein_name": "Tripartite motif-containing protein 51G", "gene_name": "TRIM51G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSGILQVFQRELICPICMNYFIDPVTIDCGHSFCRPCFYLNWQDMAVLAQCSKCKKTTRQRNLKTNICLKNMASIARKASLRQFLSSEEQICGTHRETKEMFCEVDKSLLCLLCSNSQEHRNHRHCPTEWAAEERREELLRKMQSLWRKMCENHRNLNMATNRIRCWKDYVSLRIEAIRAEYHKMVAFFHEEEQRHLERLQKEGEDIFQQLNESKARMEHSRELLRGMYEDLRQMCHKAVVELFQSFGDILQRYESLLLQVSEPVNPEFSAGPIIGLMDRLKGFRVYLTLQHARASSHIFLHGDLRSMKVGCDPQHDPNITDKSECFLQWGADFFISGKFYWEFNMGHSWNWAFGVCNNYWKEKRQNDMIDGEVGLFLLGCVKEDTHCSLFTTSPLVMQYVPRPTDTVGLFLDCEGRTVSFVDVDRSSLIYTIPNCSFSPPLWPIICCSHF", "length": 452 }, "evidence": [ { "id": "HGNC:43972", "url": "https://alliancegenome.org/gene/HGNC:43972#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A8M1NGD4-1", "protein_name": "Tripartite motif containing 35-31", "gene_name": "trim35-31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASLSEENFSCPICHEIFKDPVVLSCSHSFCRECLQQYWRAVDIQECPVCRRRSSRDDPPNNLVLKNLCESFLKERKEKPSPGSEEICSLHGEKLKLFCLEDKQPVCLVCRDSEQHDNHKFRPIGEVVSSHKEELNTGLKSLQEKLRHKETIKEEFEKTVQHITAQADHSEHQIKQEFEKLHQFLKDREKGTITALRKEEKQKKQMMKEKLEEINTHISALSDSIRDTKEMLKANDVCFLKEFPGSMERVQISQPDPQTPSGALIHVSQYLGNLQYRVWRKMEDIVHYTPVILDPNTANSHIVLSEDLTSVRESENKQWLPDNPERFDYPCVLGSVGFCSGKHRWDVEVKESRCWSVGVTTASNQRKRDVFFNTDVWSVWHDPYGLIKSSSNEFPVEQYLECVRVELDYDRGTVCFSDPVNNTHLHTFTTTFTDAVFPFLWCDLFSSLRILPFNR", "length": 455 }, "evidence": [ { "id": "RGD:1564642", "url": "https://alliancegenome.org/gene/RGD:1564642#orthology", "database": "AGR" }, { "id": "RGD:1305337", "url": "https://alliancegenome.org/gene/RGD:1305337#orthology", "database": "AGR" }, { "id": "MGI:1914104", "url": "https://alliancegenome.org/gene/MGI:1914104#orthology", "database": "AGR" }, { "id": "HGNC:26698", "url": "https://alliancegenome.org/gene/HGNC:26698#orthology", "database": "AGR" }, { "id": "HGNC:16285", "url": "https://alliancegenome.org/gene/HGNC:16285#orthology", "database": "AGR" }, { "id": "HGNC:43972", "url": "https://alliancegenome.org/gene/HGNC:43972#orthology", "database": "AGR" }, { "id": "HGNC:37147", "url": "https://alliancegenome.org/gene/HGNC:37147#orthology", "database": "AGR" }, { "id": "HGNC:37148", "url": "https://alliancegenome.org/gene/HGNC:37148#orthology", "database": "AGR" }, { "id": "HGNC:13431", "url": "https://alliancegenome.org/gene/HGNC:13431#orthology", "database": "AGR" }, { "id": "HGNC:34228", "url": "https://alliancegenome.org/gene/HGNC:34228#orthology", "database": "AGR" }, { "id": "HGNC:19015", "url": "https://alliancegenome.org/gene/HGNC:19015#orthology", "database": "AGR" }, { "id": "HGNC:14663", "url": "https://alliancegenome.org/gene/HGNC:14663#orthology", "database": "AGR" }, { "id": "HGNC:37217", "url": "https://alliancegenome.org/gene/HGNC:37217#orthology", "database": "AGR" }, { "id": "HGNC:37146", "url": "https://alliancegenome.org/gene/HGNC:37146#orthology", "database": "AGR" }, { "id": "HGNC:43973", "url": "https://alliancegenome.org/gene/HGNC:43973#orthology", "database": "AGR" }, { "id": "HGNC:38877", "url": "https://alliancegenome.org/gene/HGNC:38877#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PZV1-1", "protein_name": "Zinc-binding protein A33", "gene_name": "trim35-14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTLWRKELLSYAFSEVKVKGRNESVGYSVGFTVSSTVECLHWGLFTVMADALSFLEEDLSCLICCDVFTDPVTLKCSHSLCENCLKSFWKTQDVLQCPVCRKECSPDEPTKSLAFRALCESFKTRKPTAVSGDVCPQHKETLKLFCFEDKQPICVVCYTSKKHENHKCSPVEEAAGNLKADLKMQMDKLQVTLDDLKKTHESCMEQAENIMEKEEIQIKKEFEKLHQFLKDEEDKWIKALKKQIKPQDGKFKARIKHLSTQITDLSERMAALWQDMEAENIPFLQNYSDTLQKLKHSSVEKRPAEAEKYQHHSPQTMIFTTWARMQNLVEQPPVILDPNTASSKQWVSADCTSVQYVLKKVHMCDNPKRLFLGVLASQGFNSGLHCWDVEVRDNNHWTLGVVGETVYRKRLYRMDPKSRFWCFRFVDGKFKKGNNPGKAIDENKRPNIIRVQLDFEKGELRFIDPFRNKNLCTFTGGFPERVFPYFCSGDLATPLNIFPANKEKF", "length": 505 }, "evidence": [ { "id": "MGI:1914104", "url": "https://alliancegenome.org/gene/MGI:1914104#orthology", "database": "AGR" }, { "id": "HGNC:43972", "url": "https://alliancegenome.org/gene/HGNC:43972#orthology", "database": "AGR" }, { "id": "HGNC:37147", "url": "https://alliancegenome.org/gene/HGNC:37147#orthology", "database": "AGR" }, { "id": "HGNC:37148", "url": "https://alliancegenome.org/gene/HGNC:37148#orthology", "database": "AGR" }, { "id": "HGNC:13431", "url": "https://alliancegenome.org/gene/HGNC:13431#orthology", "database": "AGR" }, { "id": "HGNC:34228", "url": "https://alliancegenome.org/gene/HGNC:34228#orthology", "database": "AGR" }, { "id": "HGNC:19015", "url": "https://alliancegenome.org/gene/HGNC:19015#orthology", "database": "AGR" }, { "id": "HGNC:14663", "url": "https://alliancegenome.org/gene/HGNC:14663#orthology", "database": "AGR" }, { "id": "HGNC:37217", "url": "https://alliancegenome.org/gene/HGNC:37217#orthology", "database": "AGR" }, { "id": "HGNC:37146", "url": "https://alliancegenome.org/gene/HGNC:37146#orthology", "database": "AGR" }, { "id": "HGNC:43973", "url": "https://alliancegenome.org/gene/HGNC:43973#orthology", "database": "AGR" }, { "id": "HGNC:38877", "url": "https://alliancegenome.org/gene/HGNC:38877#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PZW6-1", "protein_name": "Zinc-binding protein A33", "gene_name": "trim35-4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSQAEYDYICPVCHEVFRVPVILPCGHSFCQRCVRQFWSGRRARECPVCRRSCRHLQPVVNLALKNLCEEFETRRKRSRPEDMCGLHQEKLKLFCLQDNQPVCVVCFTSQQHDQHTLRPVAEAAAPRKDQLSAALKILQEKLQHREKTKEELQKTLQHIRAQAEQTERQIRLQFQKLHQFLRDEEEASVSAVREEEEEKQQMMKEKLEDINKHISDLSHAIRDTEESMSRSSIRFLQEFTVSMERVQISPPDPQIPAGALINESRHLGNLMHRVWRKMENIVQHTPVVLDPNTAHPDLLVSADLSSVRWSWSKRALPDNAERFDHHPCVLASEGVRSGTLSWAVEVRQSSDWTLGVTTELNQRKGWDFFSADVWSVCYDEYSVSERPVFGVRVKQRLERVRVDLDYDGGTISFSDAVNNTHIHTFSSNFTHTLIPFFSCYTIFNLKILPSNSQQQLNTNAELTP", "length": 465 }, "evidence": [ { "id": "RGD:1564642", "url": "https://alliancegenome.org/gene/RGD:1564642#orthology", "database": "AGR" }, { "id": "RGD:1305337", "url": "https://alliancegenome.org/gene/RGD:1305337#orthology", "database": "AGR" }, { "id": "MGI:1914104", "url": "https://alliancegenome.org/gene/MGI:1914104#orthology", "database": "AGR" }, { "id": "HGNC:26698", "url": "https://alliancegenome.org/gene/HGNC:26698#orthology", "database": "AGR" }, { "id": "HGNC:16285", "url": "https://alliancegenome.org/gene/HGNC:16285#orthology", "database": "AGR" }, { "id": "HGNC:43972", "url": "https://alliancegenome.org/gene/HGNC:43972#orthology", "database": "AGR" }, { "id": "HGNC:37147", "url": "https://alliancegenome.org/gene/HGNC:37147#orthology", "database": "AGR" }, { "id": "HGNC:37148", "url": "https://alliancegenome.org/gene/HGNC:37148#orthology", "database": "AGR" }, { "id": "HGNC:13431", "url": "https://alliancegenome.org/gene/HGNC:13431#orthology", "database": "AGR" }, { "id": "HGNC:34228", "url": "https://alliancegenome.org/gene/HGNC:34228#orthology", "database": "AGR" }, { "id": "HGNC:19015", "url": "https://alliancegenome.org/gene/HGNC:19015#orthology", "database": "AGR" }, { "id": "HGNC:14663", "url": "https://alliancegenome.org/gene/HGNC:14663#orthology", "database": "AGR" }, { "id": "HGNC:37217", "url": "https://alliancegenome.org/gene/HGNC:37217#orthology", "database": "AGR" }, { "id": "HGNC:37146", "url": "https://alliancegenome.org/gene/HGNC:37146#orthology", "database": "AGR" }, { "id": "HGNC:43973", "url": "https://alliancegenome.org/gene/HGNC:43973#orthology", "database": "AGR" }, { "id": "HGNC:38877", "url": "https://alliancegenome.org/gene/HGNC:38877#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q7P5-1", "protein_name": "E3 ubiquitin-protein ligase TRIM35-like", "gene_name": "trim35-44", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASSAEYDYSCPVCHDIFKTPVILSCTHSFCKECLQQFWRSKNTQECPVCRRRSSKKDLPVNLALKNLCESFLKERNERRSSGSEEICSLHSEKLKLFCLEDKQPVCLVCRDSEKHLGHTFRPLSEMAAENMEELNTALKSLQEKLKHNENIKEEFEKSVQHIKAQAEHTERQIKQQFKKLHQFLRDEEEATITALREEEEQKKQMMKEKLEEMNTHISALSHTIKDTEEMLKANDVCFLKEFPVSMERVQISQPDPQMPSGALIHVSRYLGNLPFRVWKKMQDIVQYTPVILDPNTAYPEFVVSDDLTSVTFSENKQPVPDNPERFDYYPFVLGSEGFNSGKHCWDVEVNRSFEWRVGVTTASNQRKGQVFLNSDVWSVYYYAHGLLATGFCGSDLDRVRVDLDYDRGTVSFSDPVNNEHLHTYTTTFTDTVFPFIYCWRSSLRILPFSSQ", "length": 452 }, "evidence": [ { "id": "RGD:1564642", "url": "https://alliancegenome.org/gene/RGD:1564642#orthology", "database": "AGR" }, { "id": "RGD:1305337", "url": "https://alliancegenome.org/gene/RGD:1305337#orthology", "database": "AGR" }, { "id": "MGI:1914104", "url": "https://alliancegenome.org/gene/MGI:1914104#orthology", "database": "AGR" }, { "id": "HGNC:26698", "url": "https://alliancegenome.org/gene/HGNC:26698#orthology", "database": "AGR" }, { "id": "HGNC:16285", "url": "https://alliancegenome.org/gene/HGNC:16285#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1QHK9-1", "protein_name": "E3 ubiquitin-protein ligase TRIM35 isoform X1", "gene_name": "trim35-10", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASLSDDFSCPVCCEIFKDPVFLSCSHSFCKECLQQYWSIMETEECPVCRRKSSRDDPPINLVLRNLCELFLKEKNERCSSVSEEICSLHGEKLKLFCLEDKQPVCVMCVTLQQHENHKFKPIDEAIPMCKEEFNAAVTSLKCKLKRREKMKGQLEETLQHIKTQAERTERQIKHEFESLHQFLRDEEEATITALREEEEQKKQMMKEKLEEMNTHISALSHTIKDSEEMLKANDVCFLKEFPVSMERVQISQPDPQTPSGALINVSCYLGNLPFRVWKKMQEIVYYTPVILDPNTANSSLVLSDDLTSVARDIIIELRPDNPERFDSYCCVLGSEGFTSGTHYWDVEVNESPGWSLGVTTASKQRKGRVFFNTDFWGVQCGPFQLPGVQVQKDLKYVRVDLDCDSGTVSFSDPVTNTHLHTFTSTLTESVFPFFCSYFTLRILPLGSIQMLEE", "length": 454 }, "evidence": [ { "id": "RGD:1564642", "url": "https://alliancegenome.org/gene/RGD:1564642#orthology", "database": "AGR" }, { "id": "RGD:1305337", "url": "https://alliancegenome.org/gene/RGD:1305337#orthology", "database": "AGR" }, { "id": "MGI:1914104", "url": "https://alliancegenome.org/gene/MGI:1914104#orthology", "database": "AGR" }, { "id": "HGNC:26698", "url": "https://alliancegenome.org/gene/HGNC:26698#orthology", "database": "AGR" }, { "id": "HGNC:16285", "url": "https://alliancegenome.org/gene/HGNC:16285#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TBF6-1", "protein_name": "Zinc-binding protein A33 isoform X1", "gene_name": "trim35-13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATKQSHLAEDLSCPICGSILQKPVVLFCRHRFCKPCLESLWNGGGSCECPLCCQPSSMGELVVNTVLEKTCEGFLEKCKNDPLACREHGETLTLFCLEHLEPTCSKCKSSMNHQGHRLYPLNEASHDCKEELKNALKPLQEKLKLFRKVKLTCEHAVNHIKNQAENTERQIREEFEALHQFLRDEEASRLSMLKQEREQKRQMMNEKIEDLENDITSLTNTIRIIEQEMRSQDIPFLKNYKDTIKRTWRIPQDPEMIAGSLLDIAKHLGSLKFKVWERMLEIIQYTPVTLDPNTAASCFLLSEDLTTLQCCSQTFKLPENPERFNVGAEVLGYEGFSSGRHSWDVEVKNNTYWVIGVASASISRKGKHVLTPAEGFWTIRLRNGEYKACTAPWSPLTMTKEPQVVRVVLDMNRSRVTFYDLRERTPLFTYTDIITPRAFPYFCSACKEYPLKVLPAWISIKSE", "length": 464 }, "evidence": [ { "id": "RGD:1564642", "url": "https://alliancegenome.org/gene/RGD:1564642#orthology", "database": "AGR" }, { "id": "RGD:1305337", "url": "https://alliancegenome.org/gene/RGD:1305337#orthology", "database": "AGR" }, { "id": "MGI:1914104", "url": "https://alliancegenome.org/gene/MGI:1914104#orthology", "database": "AGR" }, { "id": "HGNC:26698", "url": "https://alliancegenome.org/gene/HGNC:26698#orthology", "database": "AGR" }, { "id": "HGNC:16285", "url": "https://alliancegenome.org/gene/HGNC:16285#orthology", "database": "AGR" }, { "id": "HGNC:43972", "url": "https://alliancegenome.org/gene/HGNC:43972#orthology", "database": "AGR" }, { "id": "HGNC:37147", "url": "https://alliancegenome.org/gene/HGNC:37147#orthology", "database": "AGR" }, { "id": "HGNC:37148", "url": "https://alliancegenome.org/gene/HGNC:37148#orthology", "database": "AGR" }, { "id": "HGNC:13431", "url": "https://alliancegenome.org/gene/HGNC:13431#orthology", "database": "AGR" }, { "id": "HGNC:34228", "url": "https://alliancegenome.org/gene/HGNC:34228#orthology", "database": "AGR" }, { "id": "HGNC:19015", "url": "https://alliancegenome.org/gene/HGNC:19015#orthology", "database": "AGR" }, { "id": "HGNC:14663", "url": "https://alliancegenome.org/gene/HGNC:14663#orthology", "database": "AGR" }, { "id": "HGNC:37217", "url": "https://alliancegenome.org/gene/HGNC:37217#orthology", "database": "AGR" }, { "id": "HGNC:37146", "url": "https://alliancegenome.org/gene/HGNC:37146#orthology", "database": "AGR" }, { "id": "HGNC:43973", "url": "https://alliancegenome.org/gene/HGNC:43973#orthology", "database": "AGR" }, { "id": "HGNC:38877", "url": "https://alliancegenome.org/gene/HGNC:38877#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A8Y3-1", "protein_name": "Tripartite motif containing 35-9", "gene_name": "trim35-9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDPVAVGDPACALHSEKLQLFCLEDKQLACLVCRDSEKHVSHTFRPIAEAVSSYKEELKTTLKSLQFKLTQELKTRGELEKTVQHIKSQADHTLHQIQHEFKKLHQFLRDEEEATITALREEEEQKKQKMKEKLEEMNTHISALSQTIKNTEEMLKANDVCFLKEFPVSMERVQISQPDPQTPSGALIHVSRYLGNLPFRVWKKMQDIVHYTPVILDPNTANPHLVLSDDLTSLRDSFLNSKPLPDNPERFDYYSCVLGSEGLNSGKHRWDVEVKKCSIWSLGLTTASNQRKGRDFFNTGVWCVSFGLYEPSGFIVKQSLERVRVDLDCDRGTVSFSDPVTNTHLHTFTTTLTESVFPFFCSIYQLRILPFRS", "length": 373 }, "evidence": [ { "id": "RGD:1564642", "url": "https://alliancegenome.org/gene/RGD:1564642#orthology", "database": "AGR" }, { "id": "MGI:1914104", "url": "https://alliancegenome.org/gene/MGI:1914104#orthology", "database": "AGR" }, { "id": "HGNC:16285", "url": "https://alliancegenome.org/gene/HGNC:16285#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TMD8-1", "protein_name": "Zinc-binding protein A33-like isoform X1", "gene_name": "si:ch73-106l15.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MASLKVSVEDISCSVCCEIFKDPVVLSCSHSFCRECLQQFWRTKGTQECVVCRRRSSRDDPPNNLVLRNLCESFHQERKEKRSSGSEEMCSLHGEKLKLFCLKDKQPVCLVCVTSQQHDNHKFRPIGEVVPAYKEELYTALKTTQKKFEQNEEMKVEFEKTVQHITAQADDTEHQIKQQFEKLHQFLRDEEAATITALREEEEQKKQMMKEKLEEINTHNSALSDSIRDTKEMLEANDVCFLKEFAGSMERVQISQPDPQTPSGALIHVSQYLGNLQYRVWKKMQDVVHYTPVILDPNTAHPILVVSDDLTSVRETDVEHLFPDNPERFDWFPCVLGSEGFSSGKHSWDVEVKERRWWSVGVTTESNQRKGKVFFNTDVWSVRYREDNQNVDDDDDADEEKDEDDDDDDEDDDDDDDDDDDDEDEDDDEEKDNEDDDDDDDDDDDDEDGDDDEDSSPNLSVSTSFNIEQDLECVRVELDYDRGTVCFSDPVTDTHLHTFTTTFTDTVFPFFTSLDPLRILPVKDQ", "length": 525 }, "evidence": [ { "id": "RGD:1564642", "url": "https://alliancegenome.org/gene/RGD:1564642#orthology", "database": "AGR" }, { "id": "RGD:1305337", "url": "https://alliancegenome.org/gene/RGD:1305337#orthology", "database": "AGR" }, { "id": "MGI:1914104", "url": "https://alliancegenome.org/gene/MGI:1914104#orthology", "database": "AGR" }, { "id": "HGNC:26698", "url": "https://alliancegenome.org/gene/HGNC:26698#orthology", "database": "AGR" }, { "id": "HGNC:16285", "url": "https://alliancegenome.org/gene/HGNC:16285#orthology", "database": "AGR" }, { "id": "HGNC:43972", "url": "https://alliancegenome.org/gene/HGNC:43972#orthology", "database": "AGR" }, { "id": "HGNC:37147", "url": "https://alliancegenome.org/gene/HGNC:37147#orthology", "database": "AGR" }, { "id": "HGNC:37148", "url": "https://alliancegenome.org/gene/HGNC:37148#orthology", "database": "AGR" }, { "id": "HGNC:13431", "url": "https://alliancegenome.org/gene/HGNC:13431#orthology", "database": "AGR" }, { "id": "HGNC:34228", "url": "https://alliancegenome.org/gene/HGNC:34228#orthology", "database": "AGR" }, { "id": "HGNC:19015", "url": "https://alliancegenome.org/gene/HGNC:19015#orthology", "database": "AGR" }, { "id": "HGNC:14663", "url": "https://alliancegenome.org/gene/HGNC:14663#orthology", "database": "AGR" }, { "id": "HGNC:37217", "url": "https://alliancegenome.org/gene/HGNC:37217#orthology", "database": "AGR" }, { "id": "HGNC:37146", "url": "https://alliancegenome.org/gene/HGNC:37146#orthology", "database": "AGR" }, { "id": "HGNC:43973", "url": "https://alliancegenome.org/gene/HGNC:43973#orthology", "database": "AGR" }, { "id": "HGNC:38877", "url": "https://alliancegenome.org/gene/HGNC:38877#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58GIM4-1", "protein_name": "E3 ubiquitin-protein ligase TRIM69 isoform X1", "gene_name": "trim69", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRRHVQTSLTKSDVMRETPANFQQDQNPETPPILSPSQQESQSRRARRTEQSMSSSLPAQNKMDKQKLRPEIPPRVSKSSAQRLSRDLTCSICLDLFKQPVSLPCDHTFCEACITSYWSGPRVKCQAGSGSCPQCRKVFHGKSYRPNRIVANIVESYCQGMEESGVRLGAVSEPAPTAPLCMRHREELKLYCEEDQELVCLVCGISQDHRAHTLVCVQDAQKRYRASLTTSANALQKELNTALECERETEEEVKKLKDHTADLKQRIEAQFSELHQFLYQEEKLLQVKLKTEERRELIRLDEHKALLSVEISRLRRAVNDIEDKLSEQDPYTLLRSIKGLLQRQPPKFERPTLTPPSLCEGRFAGPLQYRVWKSLKGSIYPVPSAITFNSKTANPWLSLTSSLTCVRYQTFNSSVQDNPQRFNAALSLMGGQGFTKGRHYWEVEVYSSTVWTVGVARESVTRKGVINTMPANGFWTLSLSYGVQYMAGTSPPTLLSLEEPLARIGVYLDYKRGLVSFYNAESMTHLYTFRDTFTETLFPYFNLGFLDKVHENEPLKVFMPKI", "length": 562 }, "evidence": [ { "id": "RGD:1564642", "url": "https://alliancegenome.org/gene/RGD:1564642#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ACD6B6D8-1", "protein_name": "Nuclear factor 7, brain isoform X1", "gene_name": "trim35-7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSLSEEDLSCPVCREVFKNPVILSCSHSFCRECLQHFWRTKGTQQCAVCRRISAHEPLCNLVLKNVCESFIKKEKPEEICSLHNKKLKLFCLEDKQPVCLVCVTSHQHDQHTFRHIEEVLQAYKEELNKALTSLQEKLKHSKKLKGEFKRTVQHITAQADDTERQIKHQFEKLHQFLRDEEEATITALREEEEQKKQMMKEKLEEINTHISALSHTIRDTEEMLKANDVCFLKEFAGSMERVRISQPDPQTPSGALIHVSQYLGNLQYRVWRKMQDIVHYTPVILDPNTAHPHLIVSDDLTSVRLTEDKHPLPDNPERFDYFECVLGSVGFSSGKHRWDVEVKDNDEWTVGVTTASKRKGEDFYDSDIWSVENVEYFANTPQDSPNSSASNCFHVKQDLEFVRVELDCDEGTVCFSDPVTNTHLHTFTATFTDSVFPFFTSLDPLRILPVKVSEHFTCNSGSSSFRHVSSCCPRLMSDQVTDVLL", "length": 486 }, "evidence": [ { "id": "RGD:1564642", "url": "https://alliancegenome.org/gene/RGD:1564642#orthology", "database": "AGR" }, { "id": "RGD:1305337", "url": "https://alliancegenome.org/gene/RGD:1305337#orthology", "database": "AGR" }, { "id": "MGI:1914104", "url": "https://alliancegenome.org/gene/MGI:1914104#orthology", "database": "AGR" }, { "id": "HGNC:26698", "url": "https://alliancegenome.org/gene/HGNC:26698#orthology", "database": "AGR" }, { "id": "HGNC:16285", "url": "https://alliancegenome.org/gene/HGNC:16285#orthology", "database": "AGR" }, { "id": "HGNC:43972", "url": "https://alliancegenome.org/gene/HGNC:43972#orthology", "database": "AGR" }, { "id": "HGNC:37147", "url": "https://alliancegenome.org/gene/HGNC:37147#orthology", "database": "AGR" }, { "id": "HGNC:37148", "url": "https://alliancegenome.org/gene/HGNC:37148#orthology", "database": "AGR" }, { "id": "HGNC:13431", "url": "https://alliancegenome.org/gene/HGNC:13431#orthology", "database": "AGR" }, { "id": "HGNC:34228", "url": "https://alliancegenome.org/gene/HGNC:34228#orthology", "database": "AGR" }, { "id": "HGNC:19015", "url": "https://alliancegenome.org/gene/HGNC:19015#orthology", "database": "AGR" }, { "id": "HGNC:14663", "url": "https://alliancegenome.org/gene/HGNC:14663#orthology", "database": "AGR" }, { "id": "HGNC:37217", "url": "https://alliancegenome.org/gene/HGNC:37217#orthology", "database": "AGR" }, { "id": "HGNC:37146", "url": "https://alliancegenome.org/gene/HGNC:37146#orthology", "database": "AGR" }, { "id": "HGNC:43973", "url": "https://alliancegenome.org/gene/HGNC:43973#orthology", "database": "AGR" }, { "id": "HGNC:38877", "url": "https://alliancegenome.org/gene/HGNC:38877#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCK2-1", "protein_name": "Tripartite motif-containing protein 43B", "gene_name": "TRIM43B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHYPIEEAAEEDREKLLKQMRILWKKIQENQRNLYEERRTAFLLRGDVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPEVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITGLVYRLNRFRVEISFHFEVTNHNIRLFEDVRSWMFRRGPLNSDRSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSWIRKNSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR", "length": 446 }, "evidence": [ { "id": "HGNC:37146", "url": "https://alliancegenome.org/gene/HGNC:37146#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NGJ6-1", "protein_name": "Tripartite motif-containing protein 64", "gene_name": "TRIM64", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKISEKPNFNTNVVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETRTFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHVPDVELLQDVRNVSARTDLAQMQKPQPVNPELTSWCITGVLDMLNNFRVDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCQDSRTADANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGQVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT", "length": 449 }, "evidence": [ { "id": "HGNC:14663", "url": "https://alliancegenome.org/gene/HGNC:14663#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NI03-1", "protein_name": "Tripartite motif-containing protein 64B", "gene_name": "TRIM64B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSDDLQVFQNELICCICVNYFIDPVTIDCGHSFCRPCLCLCSEEGRAPMRCPSCRKTSEKPNFNTNLVLKKLSSLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECREKLIKEMDYLWEINQETRNNLNQETSTFHSLKDYVSVRKRIITIQYQKMPIFLDEEEQRHLQALEREAEELFQQLQDSQVRMTQHLERMKDMYRELWETCHMPDVVLLQDVRNVSARTDLAQMQKPQPVNPELTSWCITGVLDMLNNFRVDSALSTEMIPCYISLSEDVRYVIFGDDHLSAPTDPQGVDSFAVWGAQAFTSGKHYWEVDVTLSSNWILGVCRDSRTADANFVIDSDERFFLISSKRSNHYSLSTNSPPLIQYVQRPLGRVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT", "length": 449 }, "evidence": [ { "id": "HGNC:37147", "url": "https://alliancegenome.org/gene/HGNC:37147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A6NLI5-1", "protein_name": "Tripartite motif-containing protein 64C", "gene_name": "TRIM64C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSDTLRVFQNELICCICVNYFIDPVTTDCVHSFCRPCLCLCSEEGRAPMRCPLCRKISEKPNFNTNVALKKLASLARQTRPQNINSSDNICVLHEETKELFCEADKRLLCGPCSESPEHMAHSHSPIGWAAEECRVQKLIKEMDYLWKINQETQNNLNQETSKFCSLVDYVSLRKVIITIQYQKMHIFLDEEEQRHLQALEREAKELFQQLQDSQVRMTQHLEGMKDMYRELWETYHMPDVELLQDVGNISARTDLAQMPKPQPVNPELTSWCITGVLDMLNNFRVDNALSTEMTPCYISLSEDVRRVIFGDDHRSAPMDPQGVESFAVWCAQAFTSGKHYWEVDVTHSSNWILGVCRDSRTADTNIVIDSDKTFFSISSKTSNHYSLSTNSPPLIQYVQRPLGWVGVFLDYDNGSVSFFDVSKGSLIYGFPPSSFSSPLRPFFCFGCT", "length": 450 }, "evidence": [ { "id": "HGNC:37148", "url": "https://alliancegenome.org/gene/HGNC:37148#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "C9J1S8-1", "protein_name": "Tripartite motif-containing protein 49D", "gene_name": "TRIM49D2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSGISQVFQRELTCPICLNYFIDPVTIDCGHSFCRPCFYLNWQDIPILTQCFECLKTTQQRNLKTNIRLKKMASRARKASLWLFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSLEHRYHRHCPAEWAAEEHREKLLKKMQSLWEKVCENQRNLNVETTRISHWKDYVNVRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKDIFHRLHLSKAKMAHRREILRGTYAELMKMCHKPDVELLQAFGDILHRSESVLLHMPQPLNLELRAGPITGLRDRLNQFRVDITLPHNEANSHIFRRGDLRSICIGCDRQNAPHITATPTSFLAWGAQTFTSGKYYWEVHVGDSWNWAFGVCNKYWKGTNQNGNIHGEEGLFSLGCVKNDIQCSLFTTSPLTLQYVPRPTNHVGLFLDCEARTVSFVDVNQSSPIHTIPNCSFSPPLRPIFCCVHL", "length": 452 }, "evidence": [ { "id": "HGNC:37217", "url": "https://alliancegenome.org/gene/HGNC:37217#orthology", "database": "AGR" }, { "id": "HGNC:43973", "url": "https://alliancegenome.org/gene/HGNC:43973#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZLN6-1", "protein_name": "Tripartite motif-containing 43A", "gene_name": "Trim43a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESDNLQASQEILTCFICLGIFTDLVLTRCGHPFCRACLLLFSADTQIPIHCPLCRHPSKPNFRTAIPGKKLISIVRKERIKKYLSSEEHKCMTHKERKTIFCDENRVLLCQLCSKSQEHRGHRHCHIEEAVLKQMEKLLKQMESLLKKIQELQENLEAEKTMTDQWMDYVTLREEMIRTEYRKLYPSLDEEEAQHIECMKNQGNTNLEELRKSEAMMVHKRSQLMKVYQELMTMSQKPYEVLQQGLDDLFRRCELVQLGMPQVMKPELSAHPNAGLTARFSFFKVKIFFQNLIILNCKMSQFFDIRRFTSRPCHQNTSLDSAGSYRASWGAMDFTTGKHYWELDLKDCEHWAVGVCSNVWLSRSHKKIGSSGAFLLVCVKEGNHYSLFTTCPVSHHYIEKPTGRVGVFLDCEGGCMSFLDVAKSSLIHSYHPEAFSLRVRPFFSTVYTRS", "length": 451 }, "evidence": [ { "id": "HGNC:43972", "url": "https://alliancegenome.org/gene/HGNC:43972#orthology", "database": "AGR" }, { "id": "HGNC:37147", "url": "https://alliancegenome.org/gene/HGNC:37147#orthology", "database": "AGR" }, { "id": "HGNC:37148", "url": "https://alliancegenome.org/gene/HGNC:37148#orthology", "database": "AGR" }, { "id": "HGNC:13431", "url": "https://alliancegenome.org/gene/HGNC:13431#orthology", "database": "AGR" }, { "id": "HGNC:34228", "url": "https://alliancegenome.org/gene/HGNC:34228#orthology", "database": "AGR" }, { "id": "HGNC:19015", "url": "https://alliancegenome.org/gene/HGNC:19015#orthology", "database": "AGR" }, { "id": "HGNC:14663", "url": "https://alliancegenome.org/gene/HGNC:14663#orthology", "database": "AGR" }, { "id": "HGNC:37217", "url": "https://alliancegenome.org/gene/HGNC:37217#orthology", "database": "AGR" }, { "id": "HGNC:37146", "url": "https://alliancegenome.org/gene/HGNC:37146#orthology", "database": "AGR" }, { "id": "HGNC:43973", "url": "https://alliancegenome.org/gene/HGNC:43973#orthology", "database": "AGR" }, { "id": "HGNC:38877", "url": "https://alliancegenome.org/gene/HGNC:38877#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A221-1", "protein_name": "Tripartite motif family-like 1", "gene_name": "Triml1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVHEKISTADLMENLREELTCFICLDYFSSPVTTECGHSFCLTCLLKSWEEHNTPLSCPECWRTLGAPHFQANERLGRLANIGRQLRCQVLQSEDEQSNSGRTPGPSRVFSDDEQSVINFSPPNHGMNRAYFSSEAEEQHKEKLQDIVNILRKRKKEAQAILNHEKERVMLCKQEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEKEEKENVKKLRENEIHLTQQVRRINKMIGRIESICQNLTLESFEEVRGAMDRYESLLFQCPETTITELSLCRITGMREMLRKFSTDITLDPATANAYLLLSDDLKSVRYGGTKQQLPDNPERFDQSATVLGAQIFTCGRHYWEVEVGKKTEWEVGICKDSVNRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVHKVGVFLDYDSGHIAFYNVTDESLIYSFPPSSFHEALRPIFSPCLPNEGTNTDPLIICHI", "length": 471 }, "evidence": [ { "id": "RGD:1305337", "url": "https://alliancegenome.org/gene/RGD:1305337#orthology", "database": "AGR" }, { "id": "HGNC:26698", "url": "https://alliancegenome.org/gene/HGNC:26698#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q977-1", "protein_name": "Bloodthirsty-related gene family, member 2", "gene_name": "btr02", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MESTLSQLSEKHFLCSLCEEIFSNPVTTPCGHSFCKACLRVYWSRSGSDECPLCRKAFGSRPRLSVNRILADVTENYRKTRLAAKSKFFSMDELQDEPKNEGEVEQMIQERVQKIEKLQNSLKLVKSTCLREVQESQRVFSNLLSTLEKSHKLVVTAVEQKQREAEKRVERLVKSLEKEILELENGQSNLEHLNDMERLKKSFSHIPRPMRDWSKVILETDPCVGFTRQTVTDFMDTVTMEAKRLSKTELKRLQKYSVDVNLNPRTAHAYLYISEDRKEVRHANKQQEVPENPKRFDRVINVMSKEAFRYGRHLWEVDVGDKTDWDLGVAKQSVNRKGKFTICPSNGFWTLSLKNGSQYVANTYPPTSFNLSHKPKRVSIYLDYDEGRVSFYCSDTGTHIYSFRDSFTDKLHPILSPGRPHGEKNTAPLIISSSCCSI", "length": 438 }, "evidence": [ { "id": "RGD:1305337", "url": "https://alliancegenome.org/gene/RGD:1305337#orthology", "database": "AGR" }, { "id": "HGNC:26698", "url": "https://alliancegenome.org/gene/HGNC:26698#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "I1YAP6-1", "protein_name": "Tripartite motif-containing protein 77", "gene_name": "TRIM77", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASAITQCSTSELTCSICTDYLTDPVTICCGHRFCSPCLCLLWEDTLTPNCCPVCREISQQMYFKRIIFAEKQVIPTRESVPCQLSSSAMLICRRHQEIKNLICETDRSLLCFLCSQSPRHATHKHYMTREADEYYRKKLLIQMKSIWKKKQKNQRNLNRETNIIGTWEVFINLRSMMISAEYPKVCQYLREEEQKHVESLAREGRIIFQQLKRSQTRMAKMGILLREMYEKLKEMSCKADVNLPQDLGDVMKRNEFLRLAMPQPVNPQLSAWTITGVSERLNFFRVYITLDRKICSNHKLLFEDLRHLQCSLDDTDMSCNPTSTQYTSSWGAQILSSGKHYWEVDVKDSCNWVIGLCREAWTKRNDMRLDSEGIFLLLCLKVDDHFSLFSTSPLLPHYIPRPQGWLGVFLDYECGIVSFVNVAQSSLICSFLSRIFYFPLRPFICHGSK", "length": 450 }, "evidence": [ { "id": "HGNC:34228", "url": "https://alliancegenome.org/gene/HGNC:34228#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CI25-1", "protein_name": "Tripartite motif-containing protein 49", "gene_name": "TRIM49", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSGILQVFQGELICPLCMNYFIDPVTIDCGHSFCRPCFYLNWQDIPFLVQCSECTKSTEQINLKTNIHLKKMASLARKVSLWLFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSQEHRYHRHRPIEWAAEEHREKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHMPQPLNPELSAGPITGLRDRLNQFRVHITLHHEEANNDIFLYEILRSMCIGCDHQDVPYFTATPRSFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCNMYRKEKNQNEKIDGKAGLFLLGCVKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCIHF", "length": 452 }, "evidence": [ { "id": "HGNC:13431", "url": "https://alliancegenome.org/gene/HGNC:13431#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0CI26-1", "protein_name": "Tripartite motif-containing protein 49C", "gene_name": "TRIM49C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNSGILQVFQGELICPLCMNYFIDPVTIDCGHSFCRPCFYLNWQDIPFLVQCSECTKSTEQINLKTNIHLKKMASLARKVSLWLFLSSEEQMCGTHRETKKIFCEVDRSLLCLLCSSSQEHRYHRHRPIEWAAEEHREKLLQKMQSLWEKACENHRNLNVETTRTRCWKDYVNLRLEAIRAEYQKMPAFHHEEEKHNLEMLKKKGKEIFHRLHLSKAKMAHRMEILRGMYEELNEMCHKPDVELLQAFGDILHRSESVLLHMPQPLNPELSAGPITGLRDRLNQFRVHITLHHEEANSDIFLYEILRSMCIGCDHQDVPYFTATPRSFLAWGVQTFTSGKYYWEVHVGDSWNWAFGVCNMYRKEKNQNEKIDGKEGLFLLGCIKNDIQCSLFTTSPLMLQYIPKPTSRVGLFLDCEAKTVSFVDVNQSSLIYTIPNCSFSPPLRPIFCCIHF", "length": 452 }, "evidence": [ { "id": "HGNC:38877", "url": "https://alliancegenome.org/gene/HGNC:38877#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P86448-1", "protein_name": "Tripartite motif-containing protein 43B", "gene_name": "Trim43b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESDNLQDPQEETLTCSICQGIFMNPVYLKCGHKFCEACLLLFQEDIKFPAYCPMCMQPFNQEYINDISLKKQVSIVRKKRLMEYLNSEEHKCVTHKAKKMIFCDKSKILLCHLCSDSQEHSGHTHCSIDVAVQEKMEELLKHMDSLWRRLKIQQNYVEKERRTTLWWLKSMKLREEVIKRVYGKQCPPLSEERDQHIECLRHQSNTTLEELRKSEATIVHERNQLTEVYRELMTMSQRPYQELLVQDLDDLFRRSKLAAKLDMPQGMIPRLRAHSIPGLTARLNSFRVKISFKHSIMFGYTSLRPFDIRLLHESTSLDSAETHRVSWGKKSFSRGKYYWEVDLKDYRRWTVGVCKDPWLRGRSYVATPTDLFLECLRKDDHYILITRIGGEHYIEKPVGQVGVFLDCEGGYVSFVDVAKSSLILSYSPGTFHCAVRPFFSAVYT", "length": 445 }, "evidence": [ { "id": "HGNC:43972", "url": "https://alliancegenome.org/gene/HGNC:43972#orthology", "database": "AGR" }, { "id": "HGNC:37147", "url": "https://alliancegenome.org/gene/HGNC:37147#orthology", "database": "AGR" }, { "id": "HGNC:37148", "url": "https://alliancegenome.org/gene/HGNC:37148#orthology", "database": "AGR" }, { "id": "HGNC:13431", "url": "https://alliancegenome.org/gene/HGNC:13431#orthology", "database": "AGR" }, { "id": "HGNC:34228", "url": "https://alliancegenome.org/gene/HGNC:34228#orthology", "database": "AGR" }, { "id": "HGNC:19015", "url": "https://alliancegenome.org/gene/HGNC:19015#orthology", "database": "AGR" }, { "id": "HGNC:14663", "url": "https://alliancegenome.org/gene/HGNC:14663#orthology", "database": "AGR" }, { "id": "HGNC:37217", "url": "https://alliancegenome.org/gene/HGNC:37217#orthology", "database": "AGR" }, { "id": "HGNC:37146", "url": "https://alliancegenome.org/gene/HGNC:37146#orthology", "database": "AGR" }, { "id": "HGNC:43973", "url": "https://alliancegenome.org/gene/HGNC:43973#orthology", "database": "AGR" }, { "id": "HGNC:38877", "url": "https://alliancegenome.org/gene/HGNC:38877#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P86449-1", "protein_name": "Tripartite motif-containing protein 43C", "gene_name": "Trim43c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESDNLQDPQEETLTCSICQGIFMDPVYLRCGHKFCETCLLLFQEDIKFPAYCPTCRQPCNQRYINDISLKKQVFIVRKKRLMEYLNSEEHKCVTHKAKKMIFCDKSKILLCHLCSDSQEHSGHTHCSIDVAVQEKMEELLKHMDSLWQRLKIQQNYVEKERRMTLWWLKSVKLREEVIKRVYGKQCPPLSEERDQHIECLRHQSNTTLEELRKSEATIVHERNQLTEVYQELMTMSQRPYQELLVQDLDDLFRRSKLAAKVDMPQGMIPRLRAHSIPGLTARLNSFRVKISFKHSIMFGYNSVRPFDIRLLHESTSLDSAKTHRVSWGKKSFSRGKYYWEVDLKDYRRWTVGVCKDPWLRGRSYVVTPTDIFLLECLRNKDHYILITRIGREHYIEKPVGQVGVFLDCEGGYVSFVDVAKSSLILSYSPGTFHCAVRPFFFAAYT", "length": 446 }, "evidence": [ { "id": "HGNC:43972", "url": "https://alliancegenome.org/gene/HGNC:43972#orthology", "database": "AGR" }, { "id": "HGNC:37147", "url": "https://alliancegenome.org/gene/HGNC:37147#orthology", "database": "AGR" }, { "id": "HGNC:37148", "url": "https://alliancegenome.org/gene/HGNC:37148#orthology", "database": "AGR" }, { "id": "HGNC:13431", "url": "https://alliancegenome.org/gene/HGNC:13431#orthology", "database": "AGR" }, { "id": "HGNC:34228", "url": "https://alliancegenome.org/gene/HGNC:34228#orthology", "database": "AGR" }, { "id": "HGNC:19015", "url": "https://alliancegenome.org/gene/HGNC:19015#orthology", "database": "AGR" }, { "id": "HGNC:14663", "url": "https://alliancegenome.org/gene/HGNC:14663#orthology", "database": "AGR" }, { "id": "HGNC:37217", "url": "https://alliancegenome.org/gene/HGNC:37217#orthology", "database": "AGR" }, { "id": "HGNC:37146", "url": "https://alliancegenome.org/gene/HGNC:37146#orthology", "database": "AGR" }, { "id": "HGNC:43973", "url": "https://alliancegenome.org/gene/HGNC:43973#orthology", "database": "AGR" }, { "id": "HGNC:38877", "url": "https://alliancegenome.org/gene/HGNC:38877#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3TL54-1", "protein_name": "Tripartite motif-containing protein 43A", "gene_name": "Trim43a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESDNLQDPQEETLTCSICQSIFMNPVYLRCGHKFCEACLLLSQEDIKFPAYCPMCMQPFNQEYINDISLKKQVSIVRKKRLMKYLNSKEHKCVTHKAKKMIFCDKSKILLCHLCSDSQEHSGHTHCSIDVAVQEKMEELLKHMDSLWRRLKIQQNYVEIERRTTLWWLSVKLREEVIKRVYGKQCPPLCEERDQHIECLRHQSNTTLEELRKSEATIVHERNQLIEVYRELMTMSQRPYQELLVQDLDDLFRRSKLAAKLDMPQGMIPRLHAHSIPGLTARLNSFRVKISFKHSIMFGYTSVRPFDIRLLHESTSLDSAETHRVSWGKKSFSRGKYYWEVDLKDHEQWTVGVRKDPWLRGRSYAATPTDLFLLECLRKEDHYILITRIGGEHYIEKPVGQVGVFLDCEGGYVSFVDVAKSSLILSYSPGTFHCAVRPFFSAVYT", "length": 445 }, "evidence": [ { "id": "HGNC:43972", "url": "https://alliancegenome.org/gene/HGNC:43972#orthology", "database": "AGR" }, { "id": "HGNC:37147", "url": "https://alliancegenome.org/gene/HGNC:37147#orthology", "database": "AGR" }, { "id": "HGNC:37148", "url": "https://alliancegenome.org/gene/HGNC:37148#orthology", "database": "AGR" }, { "id": "HGNC:13431", "url": "https://alliancegenome.org/gene/HGNC:13431#orthology", "database": "AGR" }, { "id": "HGNC:34228", "url": "https://alliancegenome.org/gene/HGNC:34228#orthology", "database": "AGR" }, { "id": "HGNC:19015", "url": "https://alliancegenome.org/gene/HGNC:19015#orthology", "database": "AGR" }, { "id": "HGNC:14663", "url": "https://alliancegenome.org/gene/HGNC:14663#orthology", "database": "AGR" }, { "id": "HGNC:37217", "url": "https://alliancegenome.org/gene/HGNC:37217#orthology", "database": "AGR" }, { "id": "HGNC:37146", "url": "https://alliancegenome.org/gene/HGNC:37146#orthology", "database": "AGR" }, { "id": "HGNC:43973", "url": "https://alliancegenome.org/gene/HGNC:43973#orthology", "database": "AGR" }, { "id": "HGNC:38877", "url": "https://alliancegenome.org/gene/HGNC:38877#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5RKG6-1", "protein_name": "E3 ubiquitin-protein ligase TRIM35", "gene_name": "Trim35", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPGPSVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTPSCPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCVEDKELLCCACQADARHQEHRVQPIKDTAQDFRAKCKNMEHVLREKAKSFWALRRTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQATVDAMKEESRKKHLLAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRRLFCTVEPAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADDLTSVINHGYRVQVENPERFSSAPCLLGSQVFSKGSHSWEVDVGGLPSWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFHAHFGEVRPYFYLGASRGDGPPEPLRICHLRVSIKEELDI", "length": 501 }, "evidence": [ { "id": "RGD:1564642", "url": "https://alliancegenome.org/gene/RGD:1564642#orthology", "database": "AGR" }, { "id": "MGI:1914104", "url": "https://alliancegenome.org/gene/MGI:1914104#orthology", "database": "AGR" }, { "id": "HGNC:16285", "url": "https://alliancegenome.org/gene/HGNC:16285#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BVP1-1", "protein_name": "Probable E3 ubiquitin-protein ligase TRIML1", "gene_name": "Triml1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSNHEKMSTTDLMENLREELTCFICLDYFSSPVTTECGHSFCLMCLLKSWEEHNTPLSCPECWRTLGAPHFQANERLGRLANIGRQLRSQVLQSEDEQSICGRMPGPSWVFSDDEQSVINVSPPSQGTNKACFSSEAEEQHKEKLQDIINILRKKKKEVQAILNHEKERVMLCKEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEREEKANMKKLRENEIQLTQQIRRLGKMIGRIESTCQNLTLESFEEVKGAMDRYESLLFQSPETTITELSLCHITGMREMLRKFSTDITLDPATANAYLLLSEDLKSVRYGGTRQQLPDNPERFDQSATVLGAQIFTCGRHYWEVEVGKKTEWEVGICKDSVNRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVHKVGVFLDYDSGHIAFYNATDESLIYSFPPTPFHEALRPIFSPCLPNEGTNTDPLIICHI", "length": 470 }, "evidence": [ { "id": "RGD:1305337", "url": "https://alliancegenome.org/gene/RGD:1305337#orthology", "database": "AGR" }, { "id": "HGNC:26698", "url": "https://alliancegenome.org/gene/HGNC:26698#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C006-1", "protein_name": "E3 ubiquitin-protein ligase TRIM35", "gene_name": "Trim35", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPGPSVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRRCVSGCWEVQTTPSCPVCKERAVPGELRTNHTLNNLVETLLREEAEGARWTGRRSPRPCRAHRAPLTLFCLEDKELLCCACQADARHQEHRVQPIKDTAQDFRAKCKNMEHVLREKAKAFWALRRTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQATLDAMKEESRKKHLQAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRRLFCTVEPAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADDLTSVINHGYRVQVENPERFSSAPCLLGSQVFSKGSHSWEVDVGGLPTWRVGVVRVQAHAQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRLRVELECEEGELSFYDSERHCHLYTFHAHFGEVRPYFYLGASRGDGPPEPLRICHLRVSIKEELDI", "length": 501 }, "evidence": [ { "id": "RGD:1564642", "url": "https://alliancegenome.org/gene/RGD:1564642#orthology", "database": "AGR" }, { "id": "MGI:1914104", "url": "https://alliancegenome.org/gene/MGI:1914104#orthology", "database": "AGR" }, { "id": "HGNC:16285", "url": "https://alliancegenome.org/gene/HGNC:16285#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N9V2-1", "protein_name": "Probable E3 ubiquitin-protein ligase TRIML1", "gene_name": "TRIML1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTADLMENLREELTCFICLDYFSSPVTTECGHSFCLVCLLRSWEEHNTPLSCPECWRTLEGPHFQSNERLGRLASIARQLRSQVLQSEDEQGSYGRMPTTAKALSDDEQGGSAFVAQSHGANRVHLSSEAEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLCQEETKTCKQVVVSEYMKMHQFLKEEEQLQLQLLEQEEKENMRKLRNNEIKLTQQIRSLSKMIAQIESSSQSSAFESLEEVRGALERSEPLLLQCPEATTTELSLCRITGMKEMLRKFSTEITLDPATANAYLVLSEDLKSVKYGGSRQQLPDNPERFDQSATVLGTQIFTSGRHYWEVEVGNKTEWEVGICKDSVSRKGNLPKPPGDLFSLIGLKIGDDYSLWVSSPLKGQHVREPVCKVGVFLDYESGHIAFYNGTDESLIYSFPQASFQEALRPIFSPCLPNEGTNTDPLTICSLNSHV", "length": 468 }, "evidence": [ { "id": "RGD:1305337", "url": "https://alliancegenome.org/gene/RGD:1305337#orthology", "database": "AGR" }, { "id": "HGNC:26698", "url": "https://alliancegenome.org/gene/HGNC:26698#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96BQ3-1", "protein_name": "Tripartite motif-containing protein 43", "gene_name": "TRIM43", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHHPIEEAAEEHREKLLKQMRILWKKIQENQRNLYEEGRTAFLWRGNVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPDVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITGLVYRLNRFRVEISFHFEVTNHNIRLFEDVRSWMFRRGPLNSDRSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSWIRKNSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR", "length": 446 }, "evidence": [ { "id": "HGNC:19015", "url": "https://alliancegenome.org/gene/HGNC:19015#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9UPQ4-1", "protein_name": "E3 ubiquitin-protein ligase TRIM35", "gene_name": "TRIM35", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MERSPDVSPGPSRSFKEELLCAVCYDPFRDAVTLRCGHNFCRGCVSRCWEVQVSPTCPVCKDRASPADLRTNHTLNNLVEKLLREEAEGARWTSYRFSRVCRLHRGQLSLFCLEDKELLCCSCQADPRHQGHRVQPVKDTAHDFRAKCRNMEHALREKAKAFWAMRRSYEAIAKHNQVEAAWLEGRIRQEFDKLREFLRVEEQAILDAMAEETRQKQLLADEKMKQLTEETEVLAHEIERLQMEMKEDDVSFLMKHKSRKRRLFCTMEPEPVQPGMLIDVCKYLGSLQYRVWKKMLASVESVPFSFDPNTAAGWLSVSDDLTSVTNHGYRVQVENPERFSSAPCLLGSRVFSQGSHAWEVALGGLQSWRVGVVRVRQDSGAEGHSHSCYHDTRSGFWYVCRTQGVEGDHCVTSDPATSPLVLAIPRRLRVELECEEGELSFYDAERHCHLYTFHARFGEVRPYFYLGGARGAGPPEPLRICPLHISVKEELDG", "length": 493 }, "evidence": [ { "id": "RGD:1564642", "url": "https://alliancegenome.org/gene/RGD:1564642#orthology", "database": "AGR" }, { "id": "MGI:1914104", "url": "https://alliancegenome.org/gene/MGI:1914104#orthology", "database": "AGR" }, { "id": "HGNC:16285", "url": "https://alliancegenome.org/gene/HGNC:16285#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-484", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-484#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV72", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV72", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72" } ], "pmid": "" }, { "name": "ubiquitin protein ligase activity", "id": "GO:0061630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0061630", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV72", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV72", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 125, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 272, "end_pos": 449, "start_aa": "Leu", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UV72", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV72" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 52, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 274, "end_pos": 276 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UV86-1", "uniprot_ac": "A0A8N7UV86", "uniprot_id": "A0A8N7UV86_DANRE", "mass": { "chemical_mass": 63285.0, "monoisotopic_mass": 63285.0 }, "refseq": { "ac": "XP_696445", "name": "E3 ubiquitin/ISG15 ligase TRIM25", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696445" }, "gene_names": [ { "name": "ftr38", "type": "recommended", "evidence": [ { "id": "A0A8N7UV86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86" } ] }, { "name": "ftr38", "type": "synonym", "evidence": [ { "id": "XP_696445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696445" } ] } ], "protein_names": [ { "name": "E3 ubiquitin/ISG15 ligase TRIM25", "type": "synonym", "evidence": [ { "id": "XP_696445", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696445" }, { "id": "A0A8N7UV86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_696445.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_696445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696445" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV86", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ftr38", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-487", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UV86", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UV86", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19769", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19769", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "568045", "url": "https://www.ncbi.nlm.nih.gov/gene/568045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:568045", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568045", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UV86", "url": "https://www.orthodb.org/?gene=A0A8N7UV86", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_696445", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696445", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UV86", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UV86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-487", "url": "https://zfin.org/ZDB-GENE-070912-487", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAESSVSLAHCKFSCSECLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQELNPGNQHKVIEATHRLKEMICQQHKKLLEIFCRTDHCCICSLCVLDGHKNHDTVSAAAQRTKKQCRLKKTQSRFQQRLQERQKELEELREAVESHKHSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSFQSLSVPPGSTDSSSFFISSQLSFNKVTESVSRLSDKLQQFCTEEMKTISDKVRFISIIPAPEPQTREQFLQYSQQFTLDPNTVNKKLVLSEGNTAVEINGSDQPYPDHPDRFDGFSQVLCKESVCGRSYWELECSSASVYLSVSYKSISRKGSGNECRFGNNDQSWSLFCSDNSFSFWHNNIKTDLRKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFYVYLAKVKICDLTV", "length": 558, "header": "tr|A0A8N7UV86-1|A0A8N7UV86_DANRE Isoform 1 of E3 ubiquitin/ISG15 ligase TRIM25 OS=Danio rerio OX=7955 GN=ftr38 PE=4 SV=1 CANONICAL=A0A8N7UV86-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UV86-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86/entry#A0A8N7UV86-1", "sequence": { "sequence": "MAESSVSLAHCKFSCSECLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQELNPGNQHKVIEATHRLKEMICQQHKKLLEIFCRTDHCCICSLCVLDGHKNHDTVSAAAQRTKKQCRLKKTQSRFQQRLQERQKELEELREAVESHKHSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSFQSLSVPPGSTDSSSFFISSQLSFNKVTESVSRLSDKLQQFCTEEMKTISDKVRFISIIPAPEPQTREQFLQYSQQFTLDPNTVNKKLVLSEGNTAVEINGSDQPYPDHPDRFDGFSQVLCKESVCGRSYWELECSSASVYLSVSYKSISRKGSGNECRFGNNDQSWSLFCSDNSFSFWHNNIKTDLRKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFYVYLAKVKICDLTV", "length": 558, "header": "tr|A0A8N7UV86-1|A0A8N7UV86_DANRE Isoform 1 of E3 ubiquitin/ISG15 ligase TRIM25 OS=Danio rerio OX=7955 GN=ftr38 PE=4 SV=1 CANONICAL=A0A8N7UV86-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:568045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568045", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1REU8-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr65", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEFSVSVAQDQFSCAVCLDLLNDPVSIPCGHSYCMSCITDCWNKKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQEIHPGNQHQLTEATHRLKEMICPQHEKLLEIFCRTDHCCICYLCLVDQHKHHDTVSAAAERTELESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSITVSFPLDFDDIVKSVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTVNNWLVLSEGNTAVENKGSVQPYPDHPDRFDYWRQVLCRESVCGRSYWELEWSGARVFLSVSYKSIKRKGRGNECLFGRNAQSWSLSCSAESFSFRHNNKNTELPKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTNTLCPGFYVYKGSKVKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RFB3-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr14l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRSSTASQSRYGTQEKPRRSGRYSSSSSRSSSRDVLCDFCMIKKNKAVKSCLTCLTSFCEAHLQAHYEYPALMKHKLVAATGQLREKICGEHDKLLEVFCRSDQMCVCVLCIMEEHKKHDIVSAAAERTEKQKQLGAKLMTSQQKIEERMKKWQDLRQAVASLKHSSQSVLDENERIFAELLRALERRHGEVKEMIRAQEVLLLTNAERHLARLEEEITLLRKKHTDLEQLSQSDDHIHFLQSWQSLSAPSGYEDLSKVTLAPHHTFDNAKKAISDLKVQMEDISKEELNKISSAVNEVKILQTVDPAKREEFFEYSCQLSIDPLTAHPNLVLSDRNTVVQMSNEPRPYPDHPDRFDYWQQALCKPGLAGGRYYWELDWRGTEVDIAVTYKGIQRKGNDKPGSFGRNDKSWSLYCSESEYSFMHNSKSTAVSVPRSSRIGVYVDYESGTLAFYSVSDKMTLLYKVQTKFTEPLYPGIGVWGYGTTVRL", "length": 489 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RJY4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr03", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDSSKMAAESSVSFAQDQFNCSICLDLLKDPVAIPCGHSYCMSCISDYWDQDEWRGVYSCPQCRQTFTPRPALGKNTMLTEVVENIRKRKLQAGDVECDVCIGKAVKSCLVCLESYCQTHFEQHEEFHSRKRHKVTDANGRLQEMICPQHDRLLEMYCRTDQRCICMLCLMNEHKTHETVLPAEERAEKQKHFNEKLQQRIQEKQKQCEELRAAVESHKRSVQAAVEDTERIFTELIRSIERSRSKVTQLIRDQGKASVSGAEGRLEQLEQEINDLRRRNTELEQLSCTDNDIHFLQSFQSLSVPPASTDSSSISSRLSFNKFKMFVSRVKEELQNSLKDEKENISRIVRNISVLPTPEYERRKKFLQYYQQLTLDSNTAYKSLRLSEGNRVVTRMKKTSNHPDRFDGFAQLLCKESVRGRCYWEVERSGKGMYVSVSYKSIRRKGQGSECKFGCNDQSWSLYCSDTKCSFRHNNEESKLPVVSSSSRIGVYVDHSAGTLSFYSVSDTMSLIHRVHTTFTQPLYPGFGVSNESQVKLCDQA", "length": 542 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RKP5-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr76", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSESSSSECVDQFSCSVCLDLLKEPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCRESFSQRPLLKKNTLIAEMMETLQKTTLQTPAAAATAVDCDVCTTEKNRAVKSCLQCLASFCQTHLQLHYESPAFMKHKLVDASRHIQENICPSHGRPLEIYCQDDHQCICCLCIINSHKTHSVVSVDSEWINKKKELEKIAVERLKLIENREKGLWELSEAVKSFKSSADEAVEKMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIHKLLTTEDQIHCLKSCESVCVLPTFEEVPFSPHSHLSFKDLSISAFREALEDACRQQTDAISREVSNVHTVKPSEPKTYNDFLQYFYQPHLDPNTAHKNLILSEENRRISYSDTDQQYPDHPERFAAYCNVLCKEGLTGRCYWEVNCHGKIWAVAVCYKGISRKGNTDDNILGYNKQSWRLSRYQKNIFFVHNSEEVSIPVFHSSRIGVYLDHRAGILSFYSVSKTMTLIHKVQTTFTELLYPAFGLGECSIRIIKQKRFLKDQK", "length": 553 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RLP4-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25 isoform X1", "gene_name": "ftr02", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAQDQFNCSICLDLLKDPVAIPCGHSYCMCCISGYWDQDEQKGVYSCPQCRQTFTPRPALGKNTMLVEVVEKLRKRKLQAARPAQCYSESADVECDVCTGDKNKATKSCLMCLNSYCQNHLEQHETFFKIKRHNLMDATGRLQEMICPQHEKLLGIFCRTDKRCICYLCTMDEHKTHDTVSAAAERTDKQKYFEETLKKRIMENQKEREELRAALESHKRSVQATVEDTERIFTELICSIERTRSEVTQVIRDQEKAAVSGAERRLKKLEQEIDDLKRRNTELEQISNTDNHIHFLQNFQSFSVPPESTDTSIRSRLSFDDLVTFVSQVKEKLQQTVKQEQKNIFHIVRHINVMPSPQNKSRNDFLQYYKRFTLASNTAHESLKLSEGNRVVTRAKNALFSFPDIFEDLTQVLCNESVSGCCYWEVEWSGRGMCASVAYKSISRKGPGYDCRFGHNDQSWGLYFSDFSCSFWHNNIHTKLPGVSSSSRIGVYVDHSTGTLSFYSVSGRMRLIHRVYTTFTQPLYPGFGVCHDSQLKLCD", "length": 546 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RLR7-1", "protein_name": "Tripartite motif-containing protein 16 isoform X1", "gene_name": "ftr33", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSKMAESSVSLAHREFSCSVCLDLLKDPVAIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQQLNPGNRHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISRRVSSISIIPAPEPQTREQFLQYSQQFTLDPNTAHTYLVLSEGNTAVENKGSVQPYPDHPDRFDCWRQVLCRESVCGRSYWELEWSGVDVLISVSYKSISRKGSGNECLFGLNDQSWSLCCSADSFSFRHNNINTDLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFWVCSRLKLCDLTV", "length": 561 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RN91-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr36", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFCPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQELNPGNQHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTELESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTANNRLILSEGNTVVDCKGSVQPYPDHPDRFDGWFQVLCKESVCRRSYWELEWSGNGVEIAVSYKSISRKGSILECRFGLNDQSWSLFCSVHSFSFWHNNKQTQLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHALYPGLCLYSRVKLCDLTV", "length": 556 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2B8U3-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr57", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEVRFSLEEFMCPVCLDLLKDPVTIPCGHSYCKTCITGCWDQEDDKRVYSCSQCREAFNPRPALAKNTILAEMVEKLKTKPPADCYAGAGDVQCDVCTGIKYKAIKSCLVCQESYCRTHFDRHEEFHSRKPHKVIDATERLQDMICRKHEKELEMYCITDQMCICLMCKEYEHKNHETMSTAAQRTEKQKELKETQMKLQQRVQQRQKDLQQLREAVESQKRCAQTAVEDTDRIFTEIIRLIERRRSELTQMIRDQQKTAVSEAEGLMKRLEKEIDHLRRRGAELEQLSHTQDHIHFLQSFQSLSAPPESTDVSFNPLLSFDDLKESVQQLKVKLEDFCKEEIRKTSDKGTPILNDPFKDTFANIVPKTTRDFLKYYSRFTLDLNTVNKYLCLSSNMITYTNTPQPYPDHPDRFDQLCQVLCRESVSGRCYWEIKWSGYGVCISVSYKGIRRKGQGKDCIFGGNDQSWCLFCYPGDYSFIHNDLKTVLPVQSISSRVGVYVDHSAGILSFYSVSNTMTLIHKVQTTFTQPLYPGFNVNGYKSSVILC", "length": 548 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAS0-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr26", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSTSVVEDQFSCSICKDLLREPVTIPCGHSYCMICITDCWSQDEQRRVYSCPQCRQTFTPRPALNKNVVMAEMVENLKKTGLKSRANYAEAGDVKCDVCAGRKRKAVKSCLLCLNSYCETHFECHEVFHSSKRHKVTDATGRIQEMICSQHDRLLEVYCRTDQKCVCLMCVMDEHKNHDTVSAEAERAEKQIQVGETQTQLQNRIQEKQSKLQQLRESVEIHKSSAQTAVDDCERIFTEIIRCIKRRRLKVTQMIRDREKTEVSRAEGLLKKVEQEIEDLKRRNTELEQLSHTDDHIHFLQSLQPLIIPAESTDSMTVSSLPSYEDVGKSVSELRKKLDDFCKEQIKLISASVSCRTQILPTTKPKTREDFLKYFHQFTLDSQSVHNNLSLSDENRVATFTASMHAYPDHPDRFDTWPQVLCRENVCGRCYWEVEWSGNHGVAIAVSYKSISRKGQGTECKFGYNDQSWRLFCSASGYIFSHNNRKRDLPVVSKIGVYVDQRAGVLSFFRVSDTKMSLIHRVQTTFTQPLYPGFGLNRDSSVKLSSMI", "length": 551 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAU1-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr34", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNQHKVTEATHKLQEMICPQHEKPLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTEQESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFFISSQLSFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISIIPAPEAQTHEQFLQYSQQFTLDPNTAHNRLVLSEGNTAVENNWSVQPYPDHPDRFDGYSQVLCRESVCGRSYWELEWSGNGVEISVSYKSISRKGSGNECLFGRNDQSWSLCCSPLSLSFYHNNINTKLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFYVNYSSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAX9-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr35", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHNYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNRHKVTEATHKLQEMICPQHEKPLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTEQESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEIEMISSRVSSISIITAPEPQTREQFLQYSQQFTLDPNTAHKYLVLSEGNTAVEDKDSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGDGVYLSVSYKSISRKGSGNECGFGHNDQSWSLCCSDYSFSFRHNNIKTKLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLMHTLHTTFTHTLYPGFCVYYSSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQJ4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr95", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCAVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHQGNRHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTAYNRLVLSEGNTAVENKRSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGEDVEISVSYKSISRKGLGNECVFGFNDQSWSLSCSAHSFIFYHNNIKTDLRKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFRVYVCSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B808-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr29", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAHHEFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFCPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHQGNRHKVTEATHKLQEMICPQHEKLLEIFCRTDHCCICYLCLVDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSPLVFDDIAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTAYNRLVLSEGNTAVENKRSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGEDVEISVSYKSISRKGSGNECVFGFNDQSWSLSCSAHSFIFYHNNIKTDLRKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFRVYVCSRLKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YUU8-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSVAHREFSCAVCLDLLKDPVSTACGHNYCMSCITNCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEMVEKLRKSKLQAAGPAQSPAASGDVECDVCSGAKNRAVKSCLVCLNSYCHTHFQLHQQLNPGNQHKVTEATHRLKKLICPQHEKPLEIFCRTDHCCICYLCTMDQHKNHNTVSAVAERTEQQRRLKNIQSSFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLSFNKVTESVSRLRDKLQQFCTEEMKTISSRVSSISIIPAPEPQTREQFLQYSQQFTLDPNTAHTYLVLSEGNTAVENKGSVQPYPDHPDRFDCWHQVLCRESVCGRSYWELEWSGVDVLISVSYKSISRKGSGNECLFGLNDQSWSLCCSADSFSFYHNNIKTDLPKPSVSSSRRGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFCVYYSSRLKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YW98-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEAGISWSQNQFSCSICLDLLKGPVTIPCGHSYCMRCISGYWDQDKQRGVYICPQCRQTFTPRPALGKNTMLAEVVEQLKKTKLQAARPAHCYSESADVECDVCTGDKNKAVKSCLVCLNSYCQNHLEQHESFFRGKRHNLMDATGRLQEMICPQHDKLLEVFCRTDQCCICLLCVDEHKNHEIVSATAERTDKQRQLEETQSKHNQRIQRKQEECVELRVAIESQKCSAQAAVEDTERIFTDLIRSIERRRSEVTQLIRDQEKAQVSAAEGRLERLKQEIDDLRRRDAELEQLSHTDHHIHFLQSFQSLSTPPGSTDSSSITVSSSLSFDDVGKSVSRLREKLEDFCREEIEKISVRGITSIQKPELKTREDFLQYYRPLTLDPNTVNNCLVLSEGNRVFEHTSTNQQYPDHPDRFDCFLQVLCRENVYGRCYWEVEWSGDVEILVAYKSISRKGLGDECGFGRNDQSWGLSCSRSRCSFCHNKKQTKLPVMSNSSRIGVYVDHSAGTLSFYSISNTMSLIHRVHTTFTQPLYPGFGIDSLYSLFSETKQKIKLSDLKI", "length": 561 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1N9-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25 isoform X1", "gene_name": "ftr73", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCLHVADCFEASAKMSESSSSEYVDQFSCPVCLDLLKEPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCRESFSQRPLLKKNTLIAEMMETLQKTALQTPAAAAVDCDVCTTEKNRAVKSCLQCLASFCQTHLQLHYESPAFMKHKLVDASRHIQENICPSHGRPLEIYCQDDHQCICCMCTDNHKGHSVVSVDSEWTSKKEELEEMKLKCLKLIKDREKGQQDLSKATKNLKSSADEAVERMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFKDVPSFTSHTHLSFKDLSISAFREALEDACQQQTDAISREVSNVHVVQTPQPKSEHDFLQYYCKLQMDSSTAHRELKLSEEKRKVSFSDEVQPYPDHPQRFDWFHYILCREGLTGRCYWEVECSGDIWGVAVCYRGIRRKGNSDDCKLGFNKVSWRLNRLQQNITYIRNKVQVRIKAGCFSRIGVYLDHRAGILSFYSVSDTNTLLYKVQTTFTEPLYPAFIIGQGSSVRIFDKRTAQMEELT", "length": 567 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PAX6-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEGRFSVDQNKFDCPICLDLLKEPVTIPCGHSYCMNCITDCWSQDEQRRVYSCPQCRQTFTPRPALNKNVVMAEMVENLKVTKVKTTDPAPSYAGPGDVECDVCTGIKYKAIKSCLLCLESYCQTHFERHEAFRTGKRHKITDASGRIQEMICLKHDKLLEVYCRTDQKCICLLCTMDEHKNHDTVSSSSERTEKQKHLEDTQRNLQQKIQEREKKIQVLKESLKTHKSSAQTAVEDSERTFTELIQSIERRRSEVTQMIRDREKTEVSLTEGLLKKLEQEIEDMKRRNTELEQLLHTDDHIHFLQRFQSLSKPLESTDLSSTAVSSGFRYEDVSKSVSQLKIKLEQICTEDIENIHGQARKMIFSALLSTSHTEPTTRKDFQQYFQQLSLDQNTAHQQICLTEDNTVATWTDRVQQYPDHPDRFDKFFGVLCRESVSGRCYWEVEWSGNERLYGVGVAVSYKTINRKGDMTTSGFGFNDQSWRLFSFKSRYTFLHDSKQTELSVVSRSSRIGVYVDHRAGILSFFSVSDTTMSLIHRVQTTFTQPLYPGFWINKGSRVKICHI", "length": 565 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PJ13-1", "protein_name": "Tripartite motif-containing protein 16 isoform X1", "gene_name": "ftr11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVCLAQEQFSCSICLDLLKDPVAIPCGHSYCMSCISDCWDQDERKGVYSCPQCRQTFTPRPALGKNTMLTEVMENIRKRKLQAGDVECDVCTGRKFKAVKSCLVCLESYCQTHFQHHEEFHSRKRHKVTDATGRLQEMICPQHEKLLEIFCRTDQCCICYLCTMDKHKNHDTVSAAAEWTDKKIQLAEMQKTTHQRMVERQKEREELRAAVESHKRSAQAAVEDTESIFTELIFSFERSCSEVTQLITDQQKAAEGRAEERLKQLEQEINDLRRRNTELEQLSHTDHHIHFLKSFQSLSSPPGSTDSSSITVSSRISFDDVGKLSHLRKKLEQFCREEIEKISSKVRDINIISISAEPKTRQEFLQYSRQLTFDPNTVNTSLVLSKKNRVIEYTDKVQQYPDHPDRFDCWPQVLCRESECGRFYWEVEWNGYIEISVSYKSISRKGRGNECVFGCNDQSWSLFCSRSRFSFRHNKQQTKLPVLSISSRIGVYVDHSAGTLSFYNVSDTMSLIYRVHTTFTQPLYPGFWVFAGSILFTTDTL", "length": 545 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PRK9-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr41", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEVRISVDQIEFMCPVCLDLLKDPVTLHCGHSYCKSCITDFWDQEYEKRIYSCPQCRQSFTPRPALAKNTMLAEVVEKLKKTKPPADCCAGAGDVQCDACTGRKYKAVKSCLQCQESYCQTHFERHEEFHSRKPHKVIDATGQLRDMICQKHGKELEIYCITDQQCICELCKEYEHKNHATVSTAEQMTEKQQELKERQVKLQQREKALRKLKNAVESQKRSAQTAVEDTEKIFTELIHSIQKKGTELTQVISSAEKTAVSQAEEHMEYLEQEIEDLRRRNAELERLSQTQEHVNFLQRFQSLPAPLESTDGYFSSFLCFDAMKESVHELKSKLENLCKEEIKMILDRVTSFVPKTRNDFLQYSIKLTLDLHTAHKCLSKKRKVVTCTKKEQPYPDHPDRFHDWPQVLCTERVRGRRYWEVEWSGDKGVCISASYKSISRTGTGNECAFGGNDHSWSLFCSPLRYLFWHNNIQSDLTVKPNSHKIGVYVNVGAGTLSFYNVSDEMSLIHTFQTTFTQPLFPGFTVGFGSSVKLKHR", "length": 537 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6I4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr94", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEARFSQDEFLCPVCLELLKDPVSLHCGHNYCKGCISGFWDQEDEKRVYSCPQCRQTFSQRPALAKNTMLAEVVEKLKKTKPPADCKAGAGDVQCDVCTGTKYKAIKSCLQCQESYCQTHFENHEEFHFRKSHKVIDATGQLQDMICQKHKKELEIYCITDQQCICELCKEFEHTTHETLSVAEQRKEKQKELKETQVKLQESLQQRQQELQQLREAVESHKRSAQTAVKDTERIFTELICSIEKRCSELTQIIRDQEKTAVSRAEGHMEWLEQEVENLRRRNAELEQLSHKKDHVQFLKSFQSFSAPPESTDVLSSSLLCFDGLSESVSQLKDKLEDFCKKELKKISDRVTKTSPKTRNDFLQYSHQFTLDLNTMNDHLRLSESNRVITGAETAQPTFDHPDKFNGWPQVLCRESVRGRCYWEIEWSGDVGVILSVSYKSISRKGFGNECAFGGNDKSWSLACFPTRYSFWHNSKRTDLSVKPISRMIGVYVDESAGILSFYGISNTISLIHTVKTTFTQPLYPGFTVDPRSSVKLC", "length": 539 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TBM3-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr37", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSVAHHEFSCAVCLDLLKDPVSTACGHNYCMSCITNCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNQHKVTEATHKLKKLICPQHEKPLEIFCRTDQLCICYLCTMDQHKNHNTVSAVAERTEQQRRLKNIQSSFQQRLQERQKELEKLKKAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSPLVFDDIAESVSHLREDLEHFGKKEIKLISRRVSSISRIPAPVPKTREQFLQYSQQFTLDPNTVNNWLVLSERNTVVKYKGSVQRYPDHPDRFNCWYQVLCRESVCGRSYWELEWSGVDVYLSVSYKSISRKGSGNECLFGYNDHSWSLWCSADSFIFYHNNKQTKLPKPSVSSTRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHALYPGFCVHYSSRVKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UV20-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X1", "gene_name": "ftr91", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESMLSQQKDQFSCSVCLDPLKQPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCREIFRQKPLLKKNTLIAEMMETLQKTALQTPAAAVDCDVCTTEKNRAVKSCLQCWASFCQTHLQLHYKSPAFMNHKLVEASRHICPNHKKPQDIYCQDDHQCICYLCMIDSHKGHRVVSVEAELINKKNKLKEMKLKCQTLIKERQRGWQELSIAMKLFKSSADEAVEKMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFEDVPSFTSHTHLSFKDLSFSAFREALEDACQQQTDAISREVSNIHVVKPPDLKTQNDFLQYFCQIHLDRNTAHKNLKVTEDNKKVSCSDKDQKYPDHPERFDGYCHVLCREGLTGRCYWEVECSGKYWAVAVCYRGISRKGVSDDCKLGFNKISWRLGYYLQNFSFIHGKAHVRLPPASRIGVYLDHKAGMLSFYSVSDTMTLLHRVQTTFTEPLYPAFYSGSGSSVKIIE", "length": 537 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UVE5-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAECSISVAQDQFSCSICLDLLKDPVAIPCGHSYCMSCISDCWDQDEQRGVYSCPQCRQTFTPRPALGKNTMLAEVVGKLKKTKLQAARPAQCYSESADVECDVCTGDKNKAVKSCLMCLNSYCQNHLEQHASFFRSKKHNLMDATGRLQEMICPQHDKLLEVFCRTDQCCICYLCTMDGHKNHNTVSAAAERTDKHRQLEETQSKLHQRIQRKQVEFEELRAAVESHKCSAQAAVEDTERIFTDLIRSIERSRSEVTQLIRDQEKAAVSEAEGRLERLEQEIDDLRRRDAELEQLSHTDHHIHFLQSFQSLSTPPGSTDSSSITVSSSLSFDDVGKSVSRLREKLEHFCREEIEKITWRMRDYKGTTPTPEPKTHQEFLQYTCWLFLDLNTMNKNLVLSKGNRVIELSSTVQQYPDHPDRFDCWHQVLCRESVCGRCYWEVEWSGSVGISVAYKSIGWKGQGTEFGYSNQSWCLFCSGSICTFVHKSKHTVLPLVSSSSRIGVYVDHSAGTLSFYSVSDTMSLIHRVHTTFTQPLYPGFELVSYNPCGSKLKLCEL", "length": 557 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58GXY0-1", "protein_name": "FinTRIM family, member 23 isoform X1", "gene_name": "ftr23", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGFSETGKCSPTLLSEMAESSISVAEDQFSCSVCLDLLKEPVTIPCGHSYCMNCITDCWNQDEQRRVYSCPQCRQTFTPRPALNKNVVMVEMVEKLKTGSRNAASYAGPGDVECDVCTGRKRKAVKSCLMCLSSYCQTHLEQHDSFFKDKRHHLINATGRLRQMICSKHDRLLEVYCHTDQKCICLLCMMDEHTGHQTVSIKTERAEKQKQLLDLQKNFQKTIQEREEEVWDLKHAVKTHKHSAQTAVEESERIFTRLFHFIERRQSEVSQMIRDRKKTEVSRAEGLLKKLEEEIEDLKRRNTELEQLSHTDDHIHFLQSFHSLSAPPESPESSDVTSLLFYDDVGETLSVLKEKLEDACKEATENMSVLETPYMEIVSTSELINRDKFLQYFHHLTLDSNTAHKYLRLSEGNRVATFIGADQSYPAHPDRFHDFSQVLCRESVCGRCYWEVEWSGEAGVGISVSYKSIRRKGEGFDCVFGFNDQSWRLSCSNSRYTLRHKQLSTKLRVPSGSNRIGVYVDHKAGILSFFNISDTMSLIHRVQTTFTQPLYPGFGINFGSTVKLKSAENL", "length": 570 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58I1B9-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X2", "gene_name": "ftr30", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTHTGSVRAERNRKFTQIPCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKQQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQQLNPGNQHKVIEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEAQTREQFLQYSQQFTLDPNTVNNCLVLSEGNTAVDYKDSVQPYPDHPDRFDCSYQVFCRESVCGRSYWELEWSGVVYLSVSYKSISRKGRNIECGFGNNDQSWSLECSPYSFSFWHNKIKTALPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFGVYSSRLKLCDLTV", "length": 562 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ACD6B7A1-1", "protein_name": "LOW QUALITY PROTEIN: tripartite motif-containing protein 16", "gene_name": "ftr42", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAETRFSQDEFLCPVCLDLLKDPVAIHCGHSYCKSCITDFWNMEDEKGIYSCPQCRQTFSPRPALAKNTMLAEVVDKLKKTTPPADCYAGAEDVQCDACTGTKYKAIKSCLQCLESYCQTHFERHEEFHSRKPHKVIDATGRLQDMICPKHEKELEVYCITDQQCICELCKEYEHKNHKTVSAAAQRTEKQKELKETLVKLQERLQQRQKDLQQLRAAVESHKQSAQTAVEDTDRIFTELIYSIEKRRSELTQMIRDQEKTTRSRAERHMEQLEQEIEDLRRRNTELEQLSHTHHHIHFLQSFQSLSAPPESTDVSFSSLLCFDGLRESVSQLKVKLEDFCIEEIEKFTERVTKTVPKTRNDFLQYSHKLTLDLNTAHKLLHLSERNRIIICTETEQPYPDHPDRFDSWRQVLCRESVRGRCYWEIEWSGIKGVCISVSYKSISRKGFGNECVFGGNDQSWGLFCSTSRYSLWHNKKRSDLPLKPISRRIGVYVDVGAGTLSFYSIFDTMSLIHTVQTTFTQPIYPGFTVDPRSSVKLC", "length": 539 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LMT9-1", "protein_name": "Tripartite motif protein 80", "gene_name": "Trim80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSAKLGSFLRKGHLDRETMKQQPQRTVRRRRSPVHRAAKYLAVIDMQKISRPTQDKSPSELSTQSSRTSLQLLMSSNSSQHLLEDQVLCPICLDVFRNPVTTACGHNFCMTCLQSFWDHQADTGETYYCPQCREAFPSRPRLCKNVILGEMVACFTLAKSQTSGPLWGLAGPTDVPCDFCSPQKLKATKSCLQCMASLCEKHLHSHFEDPLFQEHQLLDPVWDLKNRLCRKHRKLRQMYCRTEGSCVCGACLLEEHQNHDTTPLEDERARKEVEVRKIQANVENQMLIIASDSQKHQGRVSFLSKLIQTMREEVNTCFSEILHEVKQLQMKVLDFVENEETVALGMLGNSMQQSHSRLLKLEGDSVWLHGLLANKSDEQFLQEFPTLKHFPACVEPLLGTNCEETQSFLQLPETLAQLRIRLMDIGLNFINQLLLKGIRMNSYEVLPATVDRKTLLQNYCNLNFDSSMASEELFLFKETHSVLNLGILLEPSTTSPLPGFKQWPQVLCCPGLSEGCHYWETEVSDSWMCLGVTYRRNPSMSGRHRRNIVYLLGRNPYSWCLEWDSLKFSVWHNNTQTVLHGSYHHTLGVALDFRAGCLSFYGVAGDVSLLYRFLTSFLEPLYPAVMVSSGASLTLKQYPEA", "length": 642 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-487", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-487#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV86", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV86", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86" } ], "pmid": "" }, { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV86", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UV86", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UV86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 189, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UV86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 365, "end_pos": 558, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UV86", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV86" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 58, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 408, "end_pos": 410 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVA3-1", "uniprot_ac": "A0A8N7UVA3", "uniprot_id": "A0A8N7UVA3_DANRE", "mass": { "chemical_mass": 27165.0, "monoisotopic_mass": 27165.0 }, "refseq": { "ac": "XP_691746", "name": "transmembrane gamma-carboxyglutamic acid protein 3 isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691746" }, "gene_names": [ { "name": "prrg3", "type": "recommended", "evidence": [ { "id": "A0A8N7UVA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" } ] }, { "name": "prrg3", "type": "synonym", "evidence": [ { "id": "XP_691746", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691746" } ] } ], "protein_names": [ { "name": "Transmembrane gamma-carboxyglutamic acid protein 3 isoform X3", "type": "synonym", "evidence": [ { "id": "A0A8N7UVA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3/entry#names_and_taxonomy" } ] }, { "name": "transmembrane gamma-carboxyglutamic acid protein 3 isoform X3", "type": "synonym", "evidence": [ { "id": "XP_691746", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691746" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_691746.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_691746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691746" } ] }, { "annotation": "Plays a role in mitochondrial and peroxisomal fission. Promotes the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface.", "evidence": [ { "database": "UniProtKB", "id": "A0AB13A7Q3", "url": "https://www.uniprot.org/uniprotkb/A0AB13A7Q3#function" }, { "database": "UniProtKB", "id": "RU368040", "url": "https://www.uniprot.org/uniprotkb/RU368040#function" }, { "database": "UniProtKB", "id": "A0AB32TEC9", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEC9#function" }, { "database": "UniProtKB", "id": "A0AB13A843", "url": "https://www.uniprot.org/uniprotkb/A0AB13A843#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "prrg3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3", "locus": {} } ], "crossref": [ { "id": "A0A8N7UVA3", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UVA3", "database": "AlphaFoldDB", "categories": [] }, { "id": "100000713", "url": "https://www.ncbi.nlm.nih.gov/gene/100000713", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000294", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000294", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008518", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008518", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017857", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017857", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039433", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039433", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100000713", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000713", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MVYRETS", "url": "https://omabrowser.org/oma/group/MVYRETS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVA3", "url": "https://www.orthodb.org/?gene=A0A8N7UVA3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16501", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16501", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16501:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16501:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24278", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24278", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24278:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24278:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00594", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00594", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05644", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05644", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_691746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691746", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13A7Q3", "url": "https://www.uniprot.org/uniprotkb/A0AB13A7Q3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13A7Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0AB13A7Q3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13A843", "url": "https://www.uniprot.org/uniprotkb/A0AB13A843", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13A843-1", "url": "https://www.uniprot.org/uniprotkb/A0AB13A843-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TEC9", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TEC9-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I7P3", "url": "https://www.uniprot.org/uniprotkb/A0AC58I7P3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58I7P3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58I7P3-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAAAFLDGKDANSLLKRFRRANGFLEEFRQGNIERECAEESCSFEEANEVFENKEQTMEFWKNRSIYTVNSNADSNSERLDFGNMVVPLVGVAVIIIALFIIWRLSITRWRLAYTQNRYLANRNTRSLPRILVHRDPLSHSENFHANDRLSVVVSGTERNGSSLATQDARHHTGHSQNNRSLYVQDPSLSVASQLSGATPPPSYEEVTGHLESSSDETTVPYNDPPPKYEEIVLENLCSN", "length": 240, "header": "tr|A0A8N7UVA3-1|A0A8N7UVA3_DANRE Isoform 1 of Transmembrane gamma-carboxyglutamic acid protein 3 isoform X3 OS=Danio rerio OX=7955 GN=prrg3 PE=4 SV=1 CANONICAL=A0A8N7UVA3-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVA3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3/entry#A0A8N7UVA3-1", "sequence": { "sequence": "MAAAFLDGKDANSLLKRFRRANGFLEEFRQGNIERECAEESCSFEEANEVFENKEQTMEFWKNRSIYTVNSNADSNSERLDFGNMVVPLVGVAVIIIALFIIWRLSITRWRLAYTQNRYLANRNTRSLPRILVHRDPLSHSENFHANDRLSVVVSGTERNGSSLATQDARHHTGHSQNNRSLYVQDPSLSVASQLSGATPPPSYEEVTGHLESSSDETTVPYNDPPPKYEEIVLENLCSN", "length": 240, "header": "tr|A0A8N7UVA3-1|A0A8N7UVA3_DANRE Isoform 1 of Transmembrane gamma-carboxyglutamic acid protein 3 isoform X3 OS=Danio rerio OX=7955 GN=prrg3 PE=4 SV=1 CANONICAL=A0A8N7UVA3-1" }, "locus": {} }, { "isoform_ac": "A0AB13A7Q3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3/entry#A0AB13A7Q3-1", "sequence": { "sequence": "MASPGYFGDGPPMRESDPYFTEVINKKMRVPERLRVGPTAQTAEHVHPRPAEDLPAAYSMHIPDRLALTDAPDLSPRPLFSKHTSSMWDVHQGSWDREAFREPVQSPLRRSYSDQGFGRTPPGTPTHSRQTAYSQTPVQQEVWLSPEEDAGTAVEFMVLRRQVVKMSRRIAGLERQSAEHRQTELLLFSLLVSACLLNGWLWLRR", "length": 205, "header": "tr|A0AB13A7Q3-1|A0A8N7UVA3_DANRE Computationally mapped isoform of Transmembrane gamma-carboxyglutamic acid protein 3 isoform X3 OS=Danio rerio OX=7955 GN=prrg3 PE=4 SV=1 CANONICAL=A0A8N7UVA3-1" }, "locus": {} }, { "isoform_ac": "A0AB13A843-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3/entry#A0AB13A843-1", "sequence": { "sequence": "MASPGYFGDGPPMRESDPYFTEVINKKMRVPERLRVGPTAQTAEHVHPRPAEDLPAAYSMHIPDRLALTDAPDLSPRPLFSKHTSSMWDVHQGSWDREAFREPVQSPLRRSYSDQGFGRTPPGTPTHSRQTAYSQTPFGYPENRPSQAVEVQPDQSRTSVQQEVWLSPEEDAGTAVEFMVLRRQVVKMSRRIAGLERQSAEHRQTELLLFSLLVSACLLNGWLWLRR", "length": 227, "header": "tr|A0AB13A843-1|A0AB13A843_DANRE Computationally mapped isoform of Mitochondrial fission factor OS=Danio rerio OX=7955 GN=prrg3 PE=3 SV=1 CANONICAL=A0A8N7UVA3-1" }, "locus": {} }, { "isoform_ac": "A0AB32TEC9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3/entry#A0AB32TEC9-1", "sequence": { "sequence": "MASPGYFGDGPPMRESDPYFTEVINKKMRVPERLRVGPTAQTAEHVHPRPAEDLPAAYSMHIPDRLALTDAPDLSPRPLFSKHTSSMWDVHQGSWDREAFREPVQSPLRRSYSDQGFGRTPPGTPTHSRQTAYSQTPRSVGRPPVTLSAPSQTKPPGPPSIPPNLLSPQSILQAARELGQQASQRLLQSVTQKYSSRFGYPENRPSQAVEVQPDQSRTSVQQEVWLSPEEDAGTAVEFMVLRRQVVKMSRRIAGLERQSAEHRQTELLLFSLLVSACLLNGWLWLRR", "length": 287, "header": "tr|A0AB32TEC9-1|A0AB32TEC9_DANRE Computationally mapped isoform of Mitochondrial fission factor OS=Danio rerio OX=7955 GN=prrg3 PE=3 SV=1 CANONICAL=A0A8N7UVA3-1" }, "locus": {} }, { "isoform_ac": "A0AC58I7P3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3/entry#A0AC58I7P3-1", "sequence": { "sequence": "MAAAFLDGKDANSLLKRFRRANGFLEEFRQGNIERECAEESCSFEEANEVFENKEQTMEFWKNRSIYTVNSNADSNSERLDFGNMVVPLVGVAVIIIALFIIWRLSITRWRLAYTQNRYLANRNTRSLPRILVHRDPLSHSENFHANDRLSVVVSGTERNGSSLATQDARHHTGHSQNNRSLYVQDPSLSVASQLSGATPPPSYEEVTGHLESSSDETTVPYNDPPPKYEEIVLEKARLNRTCEECICVHIYACLQHSFGLAFVLVRMCHRSHRLCLHA", "length": 279, "header": "tr|A0AC58I7P3-1|A0AC58I7P3_DANRE Computationally mapped isoform of Transmembrane gamma-carboxyglutamic acid protein 3 isoform X2 OS=Danio rerio OX=7955 GN=prrg3 PE=4 SV=1 CANONICAL=A0A8N7UVA3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0AB13A7Q3", "url": "https://www.uniprot.org/uniprotkb/A0AB13A7Q3" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100000713", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000713", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A480F4L7-1", "protein_name": "Proline rich and Gla domain 3", "gene_name": "PRRG3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAVFLEAKNAHSVLKRFPRANEFLEELRQGTIERECMEEICSYEEVKEVFEDKEKTMEFWKGYPNAVYSVRDPAQSSDAMYVVVPLLGVALLIVIALFIIWRCQLQKATRHHPSYAQNRYLASRAGHSLPRVMVYRGTVHSQGESSGHREAGSHPQVVLGPSRGGRTTVRLESTLYLPELSLSRLSSATPPPSYEEVTAPQESSSEEASVSYSDPPPKYEEIVAANPGSDK", "length": 231 }, "evidence": [ { "id": "A0A8N7UVA3", "url": "https://omabrowser.org/oma/group/A0A8N7UVA3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YXZ7-1", "protein_name": "Proline rich and Gla domain 3", "gene_name": "PRRG3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRLETSTAKRGSMAMFLGARNAHSILKRFPRANGFLEEIRQGTIERECMEEVCSYEEVKEVFENKEKTMEFWKGYTNSVYSVKDPGHSTERSDAMYVVVPLLGVALLIVIALFIIWRCQLQKATRHRPSYAQNRYLASRTGRSLPRVMVYRERSQSQGETQYQREAGNRGAGDSRAGGTPQQDGTLCPPEHSVSVLSRLSSATPPPSYEEVTGHPESSSGEETSISYNDPPPKYEEIVAAAPTAGK", "length": 246 }, "evidence": [ { "id": "A0A8N7UVA3", "url": "https://omabrowser.org/oma/group/A0A8N7UVA3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "M0R4Y6-1", "protein_name": "Proline rich and Gla domain 3", "gene_name": "Prrg3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVFLEAKNAHAVLKRFPRANEFLEELRQGTIERECMEEICSYEEVKEVFENKEKTMEFWKGYPNAVYSVRDPSQSSDAMYVVVPLLGVVLLIVIALFIIWRCQLQKATRHHPSYAQNRYLASRAGHNLPRVMVYRGTVHSQGESSGHRETGNNPQIVLGPSRGGRTTVRLESTLYLPELSLSRLSSATPPPSYEEVTAPQEATSEEASVSYSDPPPKYEEIVAASPSGDK", "length": 231 }, "evidence": [ { "id": "A0A8N7UVA3", "url": "https://omabrowser.org/oma/group/A0A8N7UVA3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PAQ9-1", "protein_name": "Transmembrane gamma-carboxyglutamic acid protein 3", "gene_name": "Prrg3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVFLEAKNAHAVLKRFPRANEFLEELRQGTIERECMEEICSYEEVKEVFENKEKTMEFWKGYPNAVYSVRDPSQSSDAMYVVVPLLGVVLLIVIALFIIWRCQLQKATRHHPSYAQNRYLASRAGHNLPRVMVYRGTVHSQGESSGHREAGNNPQIVMGPSRGGRTTVRLESTLYLPELSLSRLSSATPPPSYEEVTAPQEGSSEEASVSYSDPPPKYEEIVAASPSADK", "length": 231 }, "evidence": [ { "id": "A0A8N7UVA3", "url": "https://omabrowser.org/oma/group/A0A8N7UVA3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BZD7-1", "protein_name": "Transmembrane gamma-carboxyglutamic acid protein 3", "gene_name": "PRRG3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVFLEAKDAHSVLKRFPRANEFLEELRQGTIERECMEEICSYEEVKEVFENKEKTMEFWKGYPNAVYSVRDPSQSSDAMYVVVPLLGVALLIVIALFIIWRCQLQKATRHHPSYAQNRYLASRAGHTLPRVMVYRGTVHSQGEPSGHREAANSPQVVLGPSRGGRTTVRLESTLYLPELSLSRLSSTTPPPSYEEVTAPQESSSEEASVSYSDPPPKYEEIVAANPGADK", "length": 231 }, "evidence": [ { "id": "A0A8N7UVA3", "url": "https://omabrowser.org/oma/group/A0A8N7UVA3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" } ], "pmid": "" }, { "name": "mitochondrial outer membrane", "id": "GO:0005741", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005741", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" } ], "pmid": "" }, { "name": "peroxisome", "id": "GO:0005777", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005777", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" } ], "pmid": "" }, { "name": "blood coagulation", "id": "GO:0007596", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007596", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" } ], "pmid": "" }, { "name": "positive regulation of protein targeting to membrane", "id": "GO:0090314", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090314", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" } ], "pmid": "" }, { "name": "mitochondrial fission", "id": "GO:0000266", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000266", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" } ], "pmid": "" }, { "name": "positive regulation of mitochondrial fission", "id": "GO:0090141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090141", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVA3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UVA3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVA3" }, { "id": "PS50998", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50998" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Gla", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 66, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8N7UVB4-1", "uniprot_ac": "A0A8N7UVB4", "uniprot_id": "A0A8N7UVB4_DANRE", "mass": { "chemical_mass": 57172.0, "monoisotopic_mass": 57172.0 }, "refseq": { "ac": "XP_692555", "name": "cytochrome P450 2K1-like isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692555" }, "gene_names": [ { "name": "cyp2k21", "type": "recommended", "evidence": [ { "id": "A0A8N7UVB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4" } ] }, { "name": "cyp2k21", "type": "synonym", "evidence": [ { "id": "XP_692555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692555" } ] } ], "protein_names": [ { "name": "Cytochrome P450 2K1-like isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UVB4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4/entry#names_and_taxonomy" } ] }, { "name": "cytochrome P450 2K1-like isoform X1", "type": "synonym", "evidence": [ { "id": "XP_692555", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692555" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_692555.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_692555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692555" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVB4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cyp2k21", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091113-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-17", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVB4", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UVB4", "database": "AlphaFoldDB", "categories": [] }, { "id": "564107", "url": "https://www.ncbi.nlm.nih.gov/gene/564107", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001128", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001128", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002401", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002401", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017972", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017972", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036396", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036396", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVB4", "url": "https://www.orthodb.org/?gene=A0A8N7UVB4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24300:SF319", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24300:SF319", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_692555", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692555", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVB4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J1D4", "url": "https://www.uniprot.org/uniprotkb/A0AC58J1D4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J1D4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J1D4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091113-17", "url": "https://zfin.org/ZDB-GENE-091113-17", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAVVESLLQFASTGTLLGALLLFLVLYLVSSGSESQKEGKEPPGPKPLPLVGNLLTLDLTRPFDTFFKLSKTYGNVFQVYLGPEKAVVLVGYKTVKEALVNYAEEFGDREIGPGFSIMNDEHGILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMWLYDIFPWLGPFLKNKRIIVENIIQSRVQMTKLITALLETLNPNDPRGFVDSFLIRKLSDEKSGKKDSYFHEENLMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGGRQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVRRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKLCAIRRS", "length": 504, "header": "tr|A0A8N7UVB4-1|A0A8N7UVB4_DANRE Isoform 1 of Cytochrome P450 2K1-like isoform X1 OS=Danio rerio OX=7955 GN=cyp2k21 PE=3 SV=1 CANONICAL=A0A8N7UVB4-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVB4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4/entry#A0A8N7UVB4-1", "sequence": { "sequence": "MAVVESLLQFASTGTLLGALLLFLVLYLVSSGSESQKEGKEPPGPKPLPLVGNLLTLDLTRPFDTFFKLSKTYGNVFQVYLGPEKAVVLVGYKTVKEALVNYAEEFGDREIGPGFSIMNDEHGILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMWLYDIFPWLGPFLKNKRIIVENIIQSRVQMTKLITALLETLNPNDPRGFVDSFLIRKLSDEKSGKKDSYFHEENLMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGGRQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVRRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKLCAIRRS", "length": 504, "header": "tr|A0A8N7UVB4-1|A0A8N7UVB4_DANRE Isoform 1 of Cytochrome P450 2K1-like isoform X1 OS=Danio rerio OX=7955 GN=cyp2k21 PE=3 SV=1 CANONICAL=A0A8N7UVB4-1" }, "locus": {} }, { "isoform_ac": "A0AC58J1D4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4/entry#A0AC58J1D4-1", "sequence": { "sequence": "MRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMWLYDIFPWLGPFLKNKRIIVENIIQSRVQMTKLITALLETLNPNDPRGFVDSFLIRKLSDEKSGKKDSYFHEENLMMTVTNLFIAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGGRQPVVEDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVRRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKLCAIRRS", "length": 370, "header": "tr|A0AC58J1D4-1|A0AC58J1D4_DANRE Computationally mapped isoform of Cytochrome P450 2K1-like isoform X2 OS=Danio rerio OX=7955 GN=cyp2k21 PE=3 SV=1 CANONICAL=A0A8N7UVB4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A087X1C5-1", "protein_name": "Cytochrome P450 2D7", "gene_name": "CYP2D7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLEALVPLAMIVAIFLLLVDLMHRHQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREAMVTRGEDTADRPPAPIYQVLGFGPRSQGVILSRYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFADQAGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLPHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAKKEKAKGSPESSFNDENLRIVVGNLFLAGMVTTSTTLAWGLLLMILHLDVQRGRRVSPGCPIVGTHVCPVRVQQEIDDVIGQVRRPEMGDQAHMPCTTAVIHEVQHFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWKKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVAAGQPRPSHSRVVSFLVTPSPYELCAVPR", "length": 515 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A0G2JTQ9-1", "protein_name": "unspecific monooxygenase", "gene_name": "Cyp2j16", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLATVGSLLAKIWSAINFWTLLLTLLTFLLLADYLKNRRPNNYPPGPWRLPFVGNLFQFDLNISHLHLRIQQFVKKYGNLISLDFGNISVVVITGLPLIKEALINNEQNFLKRPIVPSRYRVFKDNGIFFANVHKWKEQRRFALTMLKNFGLGKKSLEQCIQEEAHHLVEVIGEEKGQPFDPHFRINNAVSNIICSITFGERFEYDDSQFQELLKLADEVICSEASMTSVLYNVFPLIFKYLPGPHQTVFKNWEKLKSIVANMIDRHRKDWNPDEPRDFVDAFLTEMTKYPDKTTTSFNEENLIATTLDLFFAGTETTSTTLRWALLYITLNPEVQEKVHSEIDRVIGHGRLPSTDDQDAMPYTNAVIHEVLRMGNIIPLNVPREVTADSTLAGFHLPKGKMILTNLTALHRDPKEWATPDTFNPEHFLENGQFKKRDSFLPFSVGKRACPGEKLAKSELFIFFTALMQNFTFKAPTNEKLSLKLRKGLSLYPVSYRICAVPR", "length": 503 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2K2P4-1", "protein_name": "unspecific monooxygenase", "gene_name": "Cyp2t1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVTCEATLLLLLILTLMLMSWGWLAHQARARMQKDLPPGPAPLPLLGNLLQLQSGHLDRVLMELSSRWGPVFTVWLGPRPAVVLSGYAALRDALVLQADAFSGRGSMAVFERFTHGNGIVFSNGPRWRTLRNFALGALKEFGVGTSTIEERILEETACVLDEFQATMGAPFDPRRLLDNAVSNVICTVVFGKRYNYGDPEFLRLLDLFSDNFRIMSSRWGETYNMFPSFMDWIPGPHHRIFKNFQELRLFISEQIQWHRQSRQTGEPRDFIDCFLEQMDKEHQDPESHFQDETLVMTTHNLFFGGTETTSTTLRYGLLIMLKYPEVAAKVQEELDATVGRTRAPSLADRAHLPYTNAVLHEIQRFISVLPLGLPRALIRDVNLRNHFLHKGTFVIPLLVSAHRDPTQFKDPDHFNPTNFLDDQGEFQNNDAFMPFAPGKRMCLGAGLARSEIFLFLTAILQKFSLLPVGSPADIDLTPQCTGLGNVPPAFQLRLVAR", "length": 497 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0G2KAI3-1", "protein_name": "Cytochrome P450 2W1", "gene_name": "Cyp2w1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELLVLCVWGILLLLGLWGLLRGCAQDPSMTRQWPPGPRPLPFLGNLHLLGVTHQDRALMELSERYGPMFTIHLGSQKTVVLSGYEVVREALVGTGHELADRPPIPIFQLIQRGGGIFFSSGVHWKVARQFTVRTLQSLGIRQPPMVGKVLQELVCLKGQLDSYGGQPFPLTLLGWAPCNITFTLLFGQRFDYQDPVFVSLLSLIDQVMVLLGSPGIQLFNTFPRLGALLRLHRPVLSKIEEVRTILRTLLEAQRPPLPNGSPARSYVEALLQQGQDDPEDMFSEANVLACTLDMVMAGTETTAATLQWAVFLMVKHPHVQGRVQEELDRVLGPGQLPQPEDQRALPYTSAVLHEVQRYITLLPHVPRCTAADIQLGGYLLPKGTPVIPLLTSVLLDKTQWETPSQFNPNHFLDAKGCFMKRGAFLPFSTGRRVCVGESLARTELFLLFAGLLQQYHLLPPPGLSPADLDLRPAPAFTMRPPAQTLRVVPRS", "length": 492 }, "evidence": [ { "id": "HGNC:20243", "url": "https://alliancegenome.org/gene/HGNC:20243#orthology", "database": "AGR" }, { "id": "MGI:3616076", "url": "https://alliancegenome.org/gene/MGI:3616076#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0R4IQ46-1", "protein_name": "Cytochrome P450 2AA12", "gene_name": "cyp2aa12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFASLLKLDLASVGLTLFLGLIFLVVFEIFRIRSYSGRFPPGPTPLPFVGTIPHFLKDSMGFIRSLSQYGEMTTVYLGRKPAMVLNTLQVIKEAIVQNGTSSSGRPSIPILTWITEGYGIVLATFGHSWRQQRRFALHTLRNFGLGKKSVEERVTEESGYLVPEMLKLEGKPFDPQHAIQNAVSNIICSIVFGDRFEYDNKRFEYLLEIIKENINQAGSLIGQVFNLIPIIKHFPGPHQKIYQNAEELKSFIRESTKSHRETLDPDSPRDFIDAYLLEMEKQKSSQDSSFHEDNMVMSVADLFLAGSDTTATTIRWGLIYLTQNPDVQERCHEEIVRVLGYDRLPCMDDRDRLPYTLATVHELQRCGNIVPSSVPHETTQPMKLRGYDIPQGTQMLINLSDILANKEHWKHPDTFNPENFLDDKGHFYRPEAFLPFSLGPRVCLGETLAKTELFLFITSLLQRIRFSWPTGEKWPNMDGIVSVVRSPEPFKIICHSRGSKE", "length": 501 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A140T8U1-1", "protein_name": "unspecific monooxygenase", "gene_name": "Cyp2j7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSTVGSLVARIWSAIHLWTLLLTLLVFRLLADYLKNRRPKNYPPGPWRLPFVGNLFQFDLDVSQLHLRIQLFVKKYGNLISIDFGNISSVVITGLPLIKEAFTDMEQNLLKRPIIPSRKHVFKDNGIIFSSGQKWKEQRRFALMILKSFGLGKKSLEQRIQEEAYHLVKAMEEEKGQPFDPHFRINSAVSNIICSINFGERFEYGDNKFQELLKITNETLSAETSMMLVLYNALPSIMKYLPGPHQTVFRNWERLKMIVYHMMESHRKDWNPDEPRDFIDAFLTEMTKYPDKTTTSFNEENLICSCLDLFIAGTETSSTALRWALLYMTLNPEVQERVHSEIDGVIGQWRQPSTGDRDSMPYTNAVIHEVLRMGNIVPLNVPREVTADSTLAGFHLPKGKMILTNLTALHRDPKEWATPDIFNPEHFLENGQFKKRESFLPFSMGKRACPGEQLARTELFIFFTALMQKFTFKAPVNEKLSLKFRMSVPISPVSYCICAVPRQ", "length": 504 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I5ZZ08-1", "protein_name": "Cytochrome P450", "gene_name": "LOC103691092", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSVLLLLAVLLSFLLLLVRGHAKIHGRLPPGPCPVPLLGNLLQMDRRGLLKSFIQLRPIWEKYGDVFTVHLGLRPVVVLCGTQTIREALVDHAEAFSGRGTIAGLEPVFQDYGIFFSSGEQWKTLRRFSMATMRDFGMRKKSVEERIKEESQCLVEELKKYQGAPLDPTFLFQCITSNIICSIVFGECFDYTDHQFLHLLDLMYQTFSLLSSIFSQVFELFPGVLKYFPGAHRQISRNLHEILDFIGQSVEKHRATLDPNAPRDFIYTYLLHMEKKSNHYTEFHHWNLLSSVLSLFFAGTETSSTTLRYGFLIMLKYPHITEKVQKEIDCVIGSHRLPTLDDRSKMPYTEAVIHEIQRFSDLAPIGTPHRVIKDTIFRGYLLPKNTEVFPILSSVLHDPQYFEQPDIFNLQHFLDANGALKIIEAFLPFSTGKRICLGESIARNELFLFFTTILQNFSVSSPVAPKDIDLTPKESGIGRIPQVYQICFLAH", "length": 493 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N004-1", "protein_name": "Cytochrome P450 2AA4", "gene_name": "cyp2aa4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFGALVKLDLSSVGLTLLLGLILLVLFEIFRIHSYKSRFPPGPTPLPFVGNLPHLLRDPMGFNRLMAQYGEMSTMYLGKKPAIVLNTIQVAKEALVQEAFAGRPCLPVIDWTSNGCGIIMATFNNSWKQQRRFALHTLRNFGLGKKSIESRVLEESQYLFAELLKDEGEPVNPHHALQNAVSNIFCSIMFGERFDYDNKRLGYLLKILNENMMLTGSAIGQIFNLAPFIKHFPGPHQKIKKNSNELYSFIEDEVEEHRKTLDPVSPRDFIDAYLLEIEKQKSNKDSTFQEENLIGSAIDLFFAGTDSTATSIRWGLLFLIQNPDVQERCHEEIVQVLGYDRLPCMDDCDRLPYTHATVHEIQRFAKTVPFGVFHETIWPTKLHGFDIPQGTMIMTNLAAIFSSKEHWKHPDTFNPENFLDENGHFSKPESYIPFSLGLRACIGESLVRTELFLFATVLLQRIHFSWPPDAKPLDMDGIVGIVRYPQTFSIICCSRDSKK", "length": 499 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PZ56-1", "protein_name": "Cytochrome P450 2J5 isoform X1", "gene_name": "cyp2j20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDMLHFYEWIDIKSILIFVCVFLLLSDFIKNKTPKNFPPGPWSLPIIGDIHHIDPSKLHLQLSEFAEKYGKIFSLRLFGPRIVVLNGYNLVKEVYTQEGDNLADRAILPLFHDIIGDKGLVASSGYKWKQQRRFALSTLRNFGLGKKNLEPSINLESGFLNEAISNEQGQPFDPRLLLNNAVSNVICALVFGNRFDYSDHKFQTLLKNINETVHLEGGICAQLYNMLPWLMRLLPGPHKRIIALWGKLIEFVGEKVNEHKVDHDPLNPRDYIDCFLDEMEKHKDDTAAGFDVENLCICTLDLFVAGTETTSTTLYWGLLYMMKYPEIQAKVQQEIDVIVGGSRQPSVSDRDNMPYTNAVIHEIQRMGNIIPINLARTTSEDTQIEKYSIPKGTMVTSNLTSVLFDESEWETPHSFNPGHFLDAEGKFRRRDAFLPFSLGKRVCLGEQLARMELFLFFSSLLQRFTFSPPAGVEPSLDYNLGATHCPQPYKLCAVPH", "length": 496 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BB11-1", "protein_name": "Cytochrome P450 2K18 isoform X1", "gene_name": "cyp2k18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVVESLLQFASTGTLLGALLLFLVLYLVSSGSGSQKEGKEPPGPKPLPLLGNLLTLDLTRAFDTFFELSKTYGNIFQVYLGPKKTVVLVGYKTVKEALVNHAEAFGDREIGPSFRIMNDEHGIVFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTEPVNYAVSNIISSIVYGSRFEYTDPQFTEMVDRANENVRVGGSISMGLYNMFPWLGPFLKNKRIVVRNIIQSRAQMTKLITALLETLNPNDPRGFVDSFLIHKLSDEKSGKKNSYFHNENLMMNVANLFVAGTDTTGTTLRWGLMLMAKYPQIQDRVQEEIDRVIGGRQPAVEDRKKLPYTDAVIHEIQRFANIVPLNLPHTTSCDITFNGYFIKKGTTVIPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFMPFSAGRRICLGESLARMELFLFFTSLLQSYRFTTPPGVSEDELDLKGIVGITLNPSPHKLCAIRR", "length": 503 }, "evidence": [ { "id": "HGNC:20243", "url": "https://alliancegenome.org/gene/HGNC:20243#orthology", "database": "AGR" }, { "id": "RGD:1564244", "url": "https://alliancegenome.org/gene/RGD:1564244#orthology", "database": "AGR" }, { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PP30-1", "protein_name": "Cytochrome P450 2K1-like", "gene_name": "cyp2k20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVVESLLQFASTSALLGALLLLLVLYLASSGSTSQKEGKEPPGPKPLPLVGNLLTLDLTRSFDTFFELSKTYGNIFQVFLGHRKTVVLVGYKTVKEALVNYAEVFGDREIGPGFKLKDEEHGILFSNGENWKEMRRFALSNLRDFGMGKRGSEEKIIEEIHHLKGEFDKFEGKPFDTTQPVNYAVSNIISSIVYGSRFEYIDPRFTEMVARANENVRVGGSFSMMIYNIFPWLGPFLKNRAVVVKNITQNRAEKKKLITALLETLNPHDPRGFVDSFLIHKLSDEKSGKKDSYFHEENLMLTVANLFAAGTDTTGTTLRWGLMLMAKYPHIQDRVQEEIDRVIGGRQPVVDDRKKLPYTDAVIHEIQRLANIVPLSLPHRTTSDITFNGYFIKKGTTVVPLLTSVLKDESEWEKPNSFYPEHFLDEKGQFVKRDAFMPFSAGRRVCLGESLARMELFLFFTSLLQSYRFTTPPGVSEDALDLKGIVGITLNPSPHKLCAIRRS", "length": 504 }, "evidence": [ { "id": "HGNC:20243", "url": "https://alliancegenome.org/gene/HGNC:20243#orthology", "database": "AGR" }, { "id": "RGD:1564244", "url": "https://alliancegenome.org/gene/RGD:1564244#orthology", "database": "AGR" }, { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TES7-1", "protein_name": "Cytochrome P450 2J4", "gene_name": "cyp2ae1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSVFSQLIGQWLDVQGFLIFLCVLLLVKHFRDVYSKNMPPGPFPLPFVGNLTNIGFSDPLGSFQRIAEKYGDVCTLYLGTKPCILMTGYETLKEAFVEQADIFTDRPYFPIVDKLGNGKGLIMSSGHMWRQQRRFALATLKYFGVGKKTLENAILQECRFLCDSLQAERGLPFDPQHLVTNAVSNIICGLVFGHRFEYDDHQFHLMQTYINNILQLPISNWGRLYNEFPTLMSLLPGKHQTAFASMSKLQPFLKEEIIKHQQDREPSSPRDYIDCYLEEIEKCKDSDAEFTEENLMFCVVDLFGAGTETTSNTLRWALAFMVKYPDVQEKVQSEIDQVIGQTRQPLMDDRTNLPYTYAVIHEIQRFANIVTFTPPRVANKDTTVGGQLIPKGVIVLPMLKPILLDKKEYSTPYDFNPAHFLDQNGKFLKKENFIPFSIGKRMCPGEQLARMELFLFFISLMQHFTFLPVEGQKLSLKGTTSVSSAPQPFQIRAVPR", "length": 497 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZZX4-1", "protein_name": "unspecific monooxygenase", "gene_name": "Cyp2ab1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSLFGGMAFLAGSFLLLKLAALCWRRSHLPPGPFPFPLLGNLWQLNFRLHPNMLFQLAQTHGNVFTVWLGSTPIVVLNGFRAVKEALVSNSEQFSGRPLTPFFRDLFGEKGVICSNGLTWRQQRRFCLTTLRELGLGKQALELQLQHEAAELAEVFHQEQGRAFDPQVPIIRSTTRVIGALVFGHHFLSEEPIFLELIRAINLGLAFASTTWRRLYDMFPWALRYLSGPHQKIFQYHEAVRGFIHHEIIRHKLRTPEAPKDFISCYLSQITKAMDDPVSTFSEENLIQVVIDLFLGGTDTTATTLHWAIIYLVHHRAIQERVQQELDEVLGTAQAVCYEDRERLPYTRAVLHEVQRLSSVVAVGAVRQCVTPTWMHGYYVSKGTIILPNLASVLCDPECWETPHQFNPGHFLDKDGDFVTNEAFLPFSAGHRVCPGEQLARMELFLMFATLLRTFRFQLPEGSQGLRLEYVFGGTLQPQPQKICAVPRLSSLSPREP", "length": 498 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A820-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2s1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAASTWALLLALLLLLLALTLPRTPARGQLPPGPTPLPLLGNLLQLRPGALYSGFLRLSKKYGPVFTVHLGPWRRVVVLVGHDAIREALGGQAEEFSGRGTLATLDKTFDGHGVFFANGERWKQLRKFTLLALRDLGMGKREGEELIQEEVQNLVKAFQRTEGRPFNPSMLLAQATSNVVCSLIFGIRLPYEDKEFQAVIQAASGTLLGISSPWGQAYEMFSWLLQPLPGPHTQLQHHLGTLAAFTIQQVQRHQGRSHTSGPARDVVDAFLQKMAQEKEDPGTEFTEKNLLMTVTYLLFAGTMTIGATIRYALLLLLKYPQVQKRVREELIQELGPSRTPSLSDRVRLPYTDAVLHEAQRLLALVPMGMPHTVTKTTSFRGYTLPKGTEVFPLIGSVLHDPAVFRNPEEFHPSRFLDDDGRIRKHEAFLPYSLGKRVCLGEGLARAELWLFFTSILQAFSLDTPCPPGDLSLKPAVRGLFNIPPDFQLQVWPTGDQSR", "length": 499 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9Q593-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSVLLLLALLTGFLLLLIRGQPKAYSRLPPGPRPLPFLGNLLQMDRGGLLKSFIKLRDKHGDVFTVHLGPRPVVMLYGTETIKEALVDHSDAFSGRGAIAVIQPIVQDYGVIFSSGERWKTLRRFSLATMRDFGMGKRSVEERIKEEAQCLVEELKKYEGAPLDPTFLFQCITANIICSIVFGERFDYTDHQFLHLLDLFYQTLSLISSFSSQLFELFSAVLKYFPGTHRQISKNIQEILNYIGHSVEQHKATLDPSAPRDFIDTYLLRMEKEKSNHHTEFHHQNLLISVLSLFFAGTETTSTTLRYGFLLMLKYPHVAEKVQKEIDQVISAHHVPTLEDRIKMPYTEAVIHEIQRFSDLAPIGLPHTVTKDTVFRGYLLPKNTEVYPILSSALHDPQYFEQPDKFNPEHFLDANGALKKSEAFLPFSTGKRICLGEGIARNELFLFFTALLQNFSLSSPVAPEDIDLTPKESGFVKIPPVYRICFLPR", "length": 491 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q5K4-1", "protein_name": "Cytochrome P450 2C44", "gene_name": "Cyp2c23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELLGLPTLALLVLVMSLSLLSVWTKMRTGGRLPPGPTPLPIIGNILQLDLKDIPASLSKLAKEYGPVYTLYFGSWPTVVLHGYDVVKEALLNQGDEFLGRGPLPIIEDSQKGHGIVFSEGERWKLLRRFSLMTLKNFGMGKRSLEERVQEEARCLVEELHKTEAQPFDPTFILACAPCNVICSILFNERFPYNDKTFLNLMDLLNKNFYQLNSIWIQMYNLWPTIMKYIPGKHREFSKRLGGVKNFILEKVKEHQESLDPANPRDYIDCFLSKIEEEKHNLKSDFNLENLAICGSNLFTAGTETTSTTLRFGLLLLVKHPEVQAKVHEELDRVIGRHQPPSMKDKMKLPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRHYVIPKGTAVFPFLSSILLDQKEFPNPEKFDPGHFLDKNGCFKKTDYFVPFSLGKRSCVGEGLARMELFLFFTTILQKFSLKALVEPKDLDIKPVTTGLFNLPPPYKLRLVPR", "length": 494 }, "evidence": [ { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q816-1", "protein_name": "Cytochrome P450 2W1", "gene_name": "Cyp2w1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALLLLGVWGILLLLGLWGLLQGCTRSPSLAPRWPPGPRPLPFLGNLHLLGVTQQDRALMELSERYGPMFTIHLGSQKTVVLSGYEVVREALVGTGHELADRPPIPIFQHIQRGGGIFFSSGARWRAGRQFTVRTLQSLGVQQPSMVGKVLQELACLKGQLDSYGGQPLPLALLGWAPCNITFTLLFGQRFDYQDPVFVSLLSLIDQVMVLLGSPGIQLFNTFPRLGAFLRLHRPVLSKIEEVRTILRTLLETRRPPLPTGGPAQSYVEALLQQGQEDDPEDMFGEANVLACTLDMVMAGTETTAATLQWAVFLMVKHPHVQGRVQEELDRVLGPGQLPQPEHQRALPYTSAVLHEVQRYITLLPHVPRCTAADIQLGGYLLPKGTPVIPLLTSVLLDKTQWETPSQFNPNHFLDAKGRFMKRGAFLPFSAGRRVCVGKSLARTELFLLFAGLLQRYRLLPPPGLSPADLDLRPAPAFTMRPPAQTLCVVPRS", "length": 493 }, "evidence": [ { "id": "HGNC:20243", "url": "https://alliancegenome.org/gene/HGNC:20243#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091113-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-17#orthology", "database": "AGR" }, { "id": "MGI:3616076", "url": "https://alliancegenome.org/gene/MGI:3616076#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LT33-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2b14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVFLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFIDTYLLHMEKEKSNHHTEFHHQNLVISVLSLFFAGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVISSHRLPTLDDRIKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDANGTLKKSEAFLPFSTGKRTCLGEGIARNELFIFFTALLQNFSLASPVAPEDIDLTPINSGAGKIPSPYQINFLSRCVG", "length": 495 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LXA4-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2ac1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSGFDFSAILALLGLILILILNIKDFMAKASKRQCPPGPKPWPVIGNLHILNLKRPYQTMLELSKKYGPIYSIQMGPRKVVVLSGYETVKDALVNYGNQFGERSQVPIFERLFDGKGIAFAHGETWKTMRRFSLSTLRDFGMGKRTIEDTIVVECQHLIQSFESHKGKPFEIKRVLNASVANVIVSMLLGKRFDYEDPQFLRLLTLIGENIKLIGNPSIVLFNIFPILGFLLRSHKKVLRNRDELFSFIRRTFLEHCHNLDKNDPRSFIDAFLVKQQEENNKSADYFNEENLLALVSNLFTAGTETTAATLRWGIILMMRYPEVQKKVHDEIHKVVGSAQPRIEHRTQMPYTDAVIHEIQRVANILPTSLPHETSTDVVFKNYYIPKGTEVITLLTSVLRDQTQWETPDAFNPAHFLSSKGRFVKKEAFMPFSVGRRMCAGEPLAKMELFLFFTSLMQKFTFQPPPGVSYLDLDLTPDIGFTIQPLPHKICALLRTSAL", "length": 499 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-091113-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-17#orthology", "database": "AGR" }, { "id": "RGD:1564244", "url": "https://alliancegenome.org/gene/RGD:1564244#orthology", "database": "AGR" }, { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q8C3-1", "protein_name": "Cytochrome P450 2K6", "gene_name": "cyp2k6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALIEAFLLQGSPTGTILGALLLFLVIYLFSSSSSSQDKEKYPPGPKPLPLLGNLHILDLKKTYLSLLELSKKYGPIYTVYLGPKKVVILSGYKIVKEALVNLSEEFGDRDISPIFHDFNRGYGIAFSNGENWREMRRFALSTLRDFGMGRKRSEELIIEEIKYVKEEFEKFGGNPFETKLPLALAISNIIASIVFSVRFEYSNTKLHRMVGRAYENMKLTGSPSVQIYNMFPWLRPIVANRNQIVKNLRDTFKQNEELINGVMKTLDPFNPRGIVDSFLIRQQKDEESGKTDSLYNSNNLYCTVNNLFGAGTDTTVTTLRWGLLLMAKYPEIQAKVQDEIERVIGGRQPVVEDRKNLPYTDAVIHEIQRFADISPIGAPRQTTCDVHLNGYFIKKGTPVFPLLVSVLRDENEWETPDSFNPKHFLNKQGQFVKKDAFMPFGAGRRVCIGESLARMELFLFFTSLLQYFRFTPPPGVSEDDLDLTPVVGFTLNPKPHQLCAVKRS", "length": 505 }, "evidence": [ { "id": "HGNC:20243", "url": "https://alliancegenome.org/gene/HGNC:20243#orthology", "database": "AGR" }, { "id": "RGD:1564244", "url": "https://alliancegenome.org/gene/RGD:1564244#orthology", "database": "AGR" }, { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F7FAJ1-1", "protein_name": "Vitamin D 25-hydroxylase", "gene_name": "Cyp2r1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGVRQGWKARPGLSETNWFPPQPWPMFQLPGVQTCAGALAGAFLLLLLVLVVRQLLRQRRPAGFPPGPPRLPFIGNICSLALSADLPHVYMRKQSRVFGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWIDHRRLAVNSFHYFGSGQKSFESKILEETWSLIDAIETYKGRPFDLKQLITNAVSNITNLILFGERFTYEDTDFQHMIELFSENVELAASAPVFLYNAFPWIGILPFGKHQRLFRNADVVYDFLSKLIEKAAVNRKPHLPQNFVDAYLDEMDKGQNDPLSTFSKENLIFSVGELIIAGTETTTNVLRWAVLFMALYPNIQGQVHKEIDLIMGHDRRPSWEDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWKDPDMFYPERFLDSSGYFTKKEALIPFSLGRRHCLGEQLARMEMFLFFTSLLQQFHLHFPHELVPNLKPRLGMTLQPQAYLICAERR", "length": 526 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3UXT0-1", "protein_name": "unspecific monooxygenase", "gene_name": "Cyp2j12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLATEDTFETAIWALLHFKTLVLAAVTFMLLAHYLKTQRPKNYPPGPWRLPFVGNLFQLDLEQPHVVIQQFVKKYGNLTSLDFGNIPSVIITGLPLIKEVFTNMEQNFLNRPITPIRKRVFNNNGLIISNGQTWKEQRRFALMTLKNFGLGKKSLEQRIQKEADCLVEAIGEEKGQPFDPHFKINSAVSNIICTFAFGERFEYEDSHFHELLRLLDEATCLEASMMCQLYNVFPSIIQYVPGSHQTVLRNWEKLKLFIYQMMESHRKDWNPDEPRDFIDAFLTEMSKYGDKTTTSFNEENLINSTLDLFFAGSETTTNTLRWALLYITTNPEVQEKVHSEIDRVIGHGRQPSTDDRDSMPYTNAVIHEVLRMGNILPMNVPREVTADSTLAGFHLPKGTMVLTNLTALHRDPKEWATPNTFNPEHFLENGQFKKRESFLPFSLGKRACPGEQLARSELFIFFTALMQKFTFKPPINEKLSLKFRNGLTLSPVSHCICAVPRH", "length": 502 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3UZ38-1", "protein_name": "unspecific monooxygenase", "gene_name": "Cyp2j8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFATIGCLVSNICSEIHLWTLLLAALTLLLLVDYIKNRHPKNYPPGPWRLPFVGNLFQFDLDVSHLHLGIQPFVKKYGNLISLDFGTIPSVIISGEPLIKEALTCMGQNFLKRPILAARQHIFKNNGIISSSGQTWKEQRRFTLMILKNFGLGKKSLEQRIQDEAHHLVEAIAEEKGRPFDPHFMINNAVSNIICSITIGERFEYEDNQFQELLKLADETLCLEASKVLMLYNVFPSIFKYLPGPHQKLFSNWEKLKLFFSHVMDSHRKDWNPSAPRDFIDAFLTEMAKYSDKTTTSFNEENLICTTLDLFFAGTETTSTALRWALLYITVNPEVQEKVHSEIDRVIGQGRHPTIDDRDSMPYTNAVIHEVLRMGNIIPLNVPREVEADITLAGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFLENGQFKKRESFLPFSVGKRGCPGEQLARSELFTFFTALMQKFTFKPPINEKLSLNFKMGVALSPVSYCICAVPR", "length": 503 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N463-1", "protein_name": "Cytochrome P450", "gene_name": "Cyp2d34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELLTGTGLWSVAIFTVIFLILVDLMHRRQHWTSRYPPGPVPWPVLGNLLQVDLDNIPYSLYKLQNRYGDVFSLQMAWKPVVVINGLKAMQEVLLTCGKDTADHPPVPIFEYLGFKSKSQGVVLASYGPEWREQRQFSVSTLRNFGLGKKSLEEWVTKEAKHLCDAFTARAGQSINPNTMLNNAVCNVIASLIFARRFEYEDPFLIRMLKMREESLKEVTGFIPGVLNTFPILLRIPGLADMVFQSQKTFMAILDNLVTENRTTWDPDQPPRNLADAFLAEIQKAKGNPESSFNDENLCMVVSDLFTAGMVTTSTTLSCALLLMILHPDVQRRVQQEIDAVIGQVRCPEMADQARMPYTNAVIHEVQRFGDIIPLNIPRITSRDIEVQDFLIPKGTILIPNMSSMLKDETVWEKPLRFYPEHFLDAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPAGQPQPSDHRIFAIPVAPYPYQVCAIMREQGH", "length": 504 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O35293-1", "protein_name": "Cytochrome P450 2F2", "gene_name": "Cyp2f2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGVSTAILLLLLAVISLSLTFTSWGKGQLPPGPKPLPILGNLLQLRSQDLLTSLTKLSKDYGSVFTVYLGPRRVIVLSGYQTVKEALVDKGEEFSGRGSYPIFFNFTKGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLDVLRKTEGKPFDPVFILSRSVSNIICSVIFGSRFDYDDERLLTIIHFINDNFQIMSSPWGEMYNIFPSLLDWVPGPHRRVFRNFGGMKDLIARSVREHQDSLDPNSPRDFIDCFLTKMVQEKQDPLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDCVVGRSRMPTLEDRASMPYTDAVIHEVQRFADVIPMNLPHRVIRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDANQSFKKSPAFMPFSAGRRLCLGEPLARMELFIYLTSILQNFTLHPLVEPEDIDLTPLSSGLGNLPRPFQLCMRIR", "length": 491 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O54749-1", "protein_name": "Cytochrome P450 2J5", "gene_name": "Cyp2j5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIMFLSSLVTTFWEALHLKTLVLAVVTFLFLINILRSRHPKNYPPGPWRLPFVGNFFQIDTKQTHLVLQQFVKKYGNVFSLELGQSPVVVVSGLPLIKEMFTHLDQNFVNRFMTPVRERITGKNGLVVSNGQTWKEQRRLALMALRNFGLGKKSLEERIQEETHHLVEAIREEGGQPFNPHLKLINAVSNIICSVTFGERFDYEDCQFQELLQLLDETMHLMGSSAGQLYNGFPCIMKYLPGPHQKIFRNWGKLKLFVSHIVKKHEKDWNPDEPRDFIDAFLIEMQKDPDRTTSFNEENLISTTLDLFLGGTETTSSTLRWALLYMSSYPEIQENVQAEIDRVIGHKRQVSLSDRESMPYTNAVIHEVQRMGNIVPLNSSREVTVDTKFNGFHLPKGTMILTNLTALHRDPKEWATPEVFNPEHFLENGQFKKRESFLPFSMGKRACLGEQLAKSELFIFFSALMQKFTFKPPINEKLSLKFRMGLILSPASYRICAIPRV", "length": 501 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O54750-1", "protein_name": "Cytochrome P450 2J6", "gene_name": "Cyp2j6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAATGSLLATIWAALHPRTLLVAAVTFLLLADYFKNRRPKNYPPGPWGLPFVGNIFQLDFGQPHLSIQPLVKKYGNIFSLNLGDITSVVITGLPLIKEALTQMEQNIMNRPLSVMQERISNKNGLIFSSGQIWKEQRRFALMTLRNFGLGKKSLEERMQEEASHLVEAIREEEGKPFNPHFSINNAVSNIICSVTFGERFDYHDSRFQEMLRLLDEVMYLETTMISQLYNIFPWIMKYIPGSHQKVFRNWEKLKLFVSCMIDDHRKDWNPDEPRDFIDAFLKEMTKYPEKTTSFNEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEVQEKVQAEIDRVIGQKRAARLADRESMPYTNAVIHEVQRMGNIIPLNVPREVAMDTNLNGFHLPKGTMVLTNLTALHRDPKEWATPDVFNPEHFLENGQFKKRESFLPFSMGKRACLGEQLARSELFIFFTSLMQKFTFNPPINEKLSPKFRNGLTLSPVSHRICAVPRQ", "length": 501 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P00176-1", "protein_name": "Cytochrome P450 2B1", "gene_name": "Cyp2b1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPTILLLLALLVGFLLLLVRGHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNSFMQLREKYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGERWKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKEKSNHHTEFHHENLMISLLSLFFAGTETSSTTLRYGFLLMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRSKMPYTDAVIHEIQRFSDLVPIGVPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDSFNPEHFLDANGALKKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDIDLTPKESGIGKIPPTYQICFSAR", "length": 491 }, "evidence": [ { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P04167-1", "protein_name": "Cytochrome P450 2B2", "gene_name": "Cyp2b2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPSILLLLALLVGFLLLLVRGHPKSRGNFPPGPRPLPLLGNLLQLDRGGLLNSFMQLREKYGDVFTVHLGPRPVVMLCGTDTIKEALVGQAEDFSGRGTIAVIEPIFKEYGVIFANGERWKALRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANIICSIVFGERFDYTDRQFLRLLELFYRTFSLLSSFSSQVFEFFSGFLKYFPGAHRQISKNLQEILDYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKEKSNHHTEFHHENLMISLLSLFFAGTETGSTTLRYGFLLMLKYPHVTEKVQKEIDQVIGSHRPPSLDDRTKMPYTDAVIHEIQRFADLAPIGLPHRVTKDTMFRGYLLPKNTEVYPILSSALHDPQYFDHPDTFNPEHFLDADGTLKKSEAFMPFSTGKRICLGEGIARNELFLFFTTILQNFSVSSHLAPKDIDLTPKESGIAKIPPTYQICFSAR", "length": 491 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P05181-1", "protein_name": "Cytochrome P450 2E1", "gene_name": "CYP2E1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSALGVTVALLVWAAFLLLVSMWRQVHSSWNLPPGPFPLPIIGNLFQLELKNIPKSFTRLAQRFGPVFTLYVGSQRMVVMHGYKAVKEALLDYKDEFSGRGDLPAFHAHRDRGIIFNNGPTWKDIRRFSLTTLRNYGMGKQGNESRIQREAHFLLEALRKTQGQPFDPTFLIGCAPCNVIADILFRKHFDYNDEKFLRLMYLFNENFHLLSTPWLQLYNNFPSFLHYLPGSHRKVIKNVAEVKEYVSERVKEHHQSLDPNCPRDLTDCLLVEMEKEKHSAERLYTMDGITVTVADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRIPAIKDRQEMPYMDAVVHEIQRFITLVPSNLPHEATRDTIFRGYLIPKGTVVVPTLDSVLYDNQEFPDPEKFKPEHFLNENGKFKYSDYFKPFSTGKRVCAGEGLARMELFLLLCAILQHFNLKPLVDPKDIDLSPIHIGFGCIPPRYKLCVIPRS", "length": 493 }, "evidence": [ { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P05182-1", "protein_name": "Cytochrome P450 2E1", "gene_name": "Cyp2e1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVLGITIALLVWVATLLVISIWKQIYNSWNLPPGPFPLPILGNIFQLDLKDIPKSFTKLAKRFGPVFTLHLGSRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFNNGPTWKDVRRFSLSILRDWGMGKQGNEARIQREAQFLVEELKKTKGQPFDPTFLIGCAPCNVIADILFNKRFDYNDKKCLRLMSLFNENFYLLSTPWIQLYNNFADYLRYLPGSHRKIMKNVSEIKQYTLEKAKEHLQSLDINCARDVTDCLLIEMEKEKHSQEPMYTMENVSVTLADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRVPAVRDRLDMPYMDAVVHEIQRFINLVPSNLPHEATRDTVFQGYVIPKGTVVIPTLDSLLYDSHEFPDPEKFKPEHFLNENGKFKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDIDLSPVTVGFGSIPPQFKLCVIPRS", "length": 493 }, "evidence": [ { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P08683-1", "protein_name": "Cytochrome P450 2C11", "gene_name": "Cyp2c11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPVLVLVLTLSSLLLLSLWRQSFGRGKLPPGPTPLPIIGNTLQIYMKDIGQSIKKFSKVYGPIFTLYLGMKPFVVLHGYEAVKEALVDLGEEFSGRGSFPVSERVNKGLGVIFSNGMQWKEIRRFSIMTLRTFGMGKRTIEDRIQEEAQCLVEELRKSKGAPFDPTFILGCAPCNVICSIIFQNRFDYKDPTFLNLMHRFNENFRLFSSPWLQVCNTFPAIIDYFPGSHNQVLKNFFYIKNYVLEKVKEHQESLDKDNPRDFIDCFLNKMEQEKHNPQSEFTLESLVATVTDMFGAGTETTSTTLRYGLLLLLKHVDVTAKVQEEIERVIGRNRSPCMKDRSQMPYTDAVVHEIQRYIDLVPTNLPHLVTRDIKFRNYFIPKGTNVIVSLSSILHDDKEFPNPEKFDPGHFLDERGNFKKSDYFMPFSAGKRICAGEALARTELFLFFTTILQNFNLKSLVDVKDIDTTPAISGFGHLPPFYEACFIPVQRADSLSSHL", "length": 500 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10610-1", "protein_name": "Cytochrome P450 2G1", "gene_name": "Cyp2g1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALGGAFSIFMTLCLSCLLILIAWKRTSRGGKLPPGPTPIPFLGNLLQVRIDATFQSFLKLQKKYGSVFTVYFGPRPVVILCGHEAVKEALVDQADDFSGRGEMPTLEKNFQGYGLALSNGERWKILRRFSLTVLRNFGMGKRSIEERIQEEAGYLLEELHKVKGAPIDPTFYLSRTVSNVICSVVFGKRFDYEDQRFRSLMKMINESFVEMSMPWAQLYDMYWGVIQYFPGRHNRLYNLIEELKDFIASRVKINEASFDPSNPRDFIDCFLIKMYQDKSDPHSEFNLKNLVLTTLNLFFAGTETVSSTLRYGFLLLMKYPEVEAKIHEEINQVIGTHRTPRVDDRAKMPYTDAVIHEIQRLTDIVPLGVPHNVIRDTHFRGYFLPKGTDVYPLIGSVLKDPKYFRYPEAFYPQHFLDEQGRFKKNDAFVAFSSGKRICVGEALARMELFLYFTSILQRFSLRSLVPPADIDIAHKISGFGNIPPTYELCFMAR", "length": 494 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10632-1", "protein_name": "Cytochrome P450 2C8", "gene_name": "CYP2C8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPFVVLVLCLSFMLLFSLWRQSCRRRKLPPGPTPLPIIGNMLQIDVKDICKSFTNFSKVYGPVFTVYFGMNPIVVFHGYEAVKEALIDNGEEFSGRGNSPISQRITKGLGIISSNGKRWKEIRRFSLTTLRNFGMGKRSIEDRVQEEAHCLVEELRKTKASPCDPTFILGCAPCNVICSVVFQKRFDYKDQNFLTLMKRFNENFRILNSPWIQVCNNFPLLIDCFPGTHNKVLKNVALTRSYIREKVKEHQASLDVNNPRDFIDCFLIKMEQEKDNQKSEFNIENLVGTVADLFVAGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTDAVVHEIQRYSDLVPTGVPHAVTTDTKFRNYLIPKGTTIMALLTSVLHDDKEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARMELFLFLTTILQNFNLKSVDDLKNLNTTAVTKGIVSLPPSYQICFIPV", "length": 490 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P10633-1", "protein_name": "Cytochrome P450 2D1", "gene_name": "Cyp2d1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELLNGTGLWSMAIFTVIFILLVDLMHRRHRWTSRYPPGPVPWPVLGNLLQVDLSNMPYSLYKLQHRYGDVFSLQKGWKPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCLGVKPRSQGVILASYGPEWREQRRFSVSTLRTFGMGKKSLEEWVTKEAGHLCDAFTAQAGQSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMVKLVEESLTEVSGFIPEVLNTFPALLRIPGLADKVFQGQKTFMALLDNLLAENRTTWDPAQPPRNLTDAFLAEVEKAKGNPESSFNDENLRMVVVDLFTAGMVTTATTLTWALLLMILYPDVQRRVQQEIDEVIGQVRCPEMTDQAHMPYTNAVIHEVQRFGDIAPLNLPRFTSCDIEVQDFVIPKGTTLIINLSSVLKDETVWEKPHRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPVGQPRPSTHGFFAFPVAPLPYQLCAVVREQGL", "length": 504 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10634-1", "protein_name": "Cytochrome P450 2D26", "gene_name": "Cyp2d26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLLIGDDLWAVVIFTAIFLLLVDLVHRHKFWTAHYPPGPVPLPGLGNLLQVDFENMPYSLYKLRSRYGDVFSLQIAWKPVVVINGLKAVRELLVTYGEDTADRPLLPIYNHLGYGNKSKGVVLAPYGPEWREQRRFSVSTLRDFGVGKKSLEQWVTEEAGHLCDTFAKEAEHPFNPSILLSKAVSNVIASLVYARRFEYEDPFFNRMLKTLKESFGEDTGFMAEVLNAIPILLQIPGLPGKVFPKLNSFIALVDKMLIEHKKSWDPAQPPRDMTDAFLAEMQKAKGNPESSFNDENLRLVVIDLFMAGMVTTSTTLSWALLLMILHPDVQRRVHEEIDEVIGQVRRPEMADQARMPFTNAVIHEVQRFADIVPTNIPHMTSRDIKFQGFLIPKGTTLIPNLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVLAGRPRPSTHGVYALPVTPQPYQLCAVAR", "length": 500 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10635-1", "protein_name": "Cytochrome P450 2D6", "gene_name": "CYP2D6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGLEALVPLAVIVAIFLLLVDLMHRRQRWAARYPPGPLPLPGLGNLLHVDFQNTPYCFDQLRRRFGDVFSLQLAWTPVVVLNGLAAVREALVTHGEDTADRPPVPITQILGFGPRSQGVFLARYGPAWREQRRFSVSTLRNLGLGKKSLEQWVTEEAACLCAAFANHSGRPFRPNGLLDKAVSNVIASLTCGRRFEYDDPRFLRLLDLAQEGLKEESGFLREVLNAVPVLLHIPALAGKVLRFQKAFLTQLDELLTEHRMTWDPAQPPRDLTEAFLAEMEKAKGNPESSFNDENLRIVVADLFSAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQAHMPYTTAVIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHFSFSVPTGQPRPSHHGVFAFLVSPSPYELCAVPR", "length": 497 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11509-1", "protein_name": "Cytochrome P450 2A6", "gene_name": "CYP2A6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLASGMLLVALLVCLTVMVLMSVWQQRKSKGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVVFSNGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDALRGTGGANIDPTFFLSRTVSNVISSIVFGDRFDYKDKEFLSLLRMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFQLLQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFIGGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNPQDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVGFATIPRNYTMSFLPR", "length": 494 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11711-1", "protein_name": "Cytochrome P450 2A1", "gene_name": "Cyp2a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLDTGLLLVVILASLSVMLLVSLWQQKIRGRLPPGPTPLPFIGNYLQLNTKDVYSSITQLSERYGPVFTIHLGPRRVVVLYGYDAVKEALVDQAEEFSGRGEQATYNTLFKGYGVAFSSGERAKQLRRLSIATLRDFGVGKRGVEERILEEAGYLIKMLQGTCGAPIDPTIYLSKTVSNVISSIVFGERFDYEDTEFLSLLQMMGQMNRFAASPTGQLYDMFHSVMKYLPGPQQQIIKVTQKLEDFMIEKVRQNHSTLDPNSPRNFIDSFLIRMQEEKNGNSEFHMKNLVMTTLSLFFAGSETVSSTLRYGFLLLMKHPDVEAKVHEEIEQVIGRNRQPQYEDHMKMPYTQAVINEIQRFSNLAPLGIPRRIIKNTTFRGFFLPKGTDVFPILGSLMTDPKFFPSPKDFDPQNFLDDKGQLKKNAAFLPFSTGKRFCLGDGLAKMELFLLLTTILQNFRFKFPMKLEDINESPKPLGFTRIIPKYTMSFMPI", "length": 492 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P11712-1", "protein_name": "Cytochrome P450 2C9", "gene_name": "CYP2C9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSLVVLVLCLSCLLLLSLWRQSSGRGKLPPGPTPLPVIGNILQIGIKDISKSLTNLSKVYGPVFTLYFGLKPIVVLHGYEAVKEALIDLGEEFSGRGIFPLAERANRGFGIVFSNGKKWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFHKRFDYKDQQFLNLMEKLNENIKILSSPWIQICNNFSPIIDYFPGTHNKLLKNVAFMKSYILEKVKEHQESMDMNNPQDFIDCFLMKMEKEKHNQPSEFTIESLENTAVDLFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRSHMPYTDAVVHEVQRYIDLLPTSLPHAVTCDIKFRNYLIPKGTTILISLTSVLHDNKEFPNPEMFDPHHFLDEGGNFKKSKYFMPFSAGKRICVGEALAGMELFLFLTSILQNFNLKSLVDPKNLDTTPVVNGFASVPPFYQLCFIPV", "length": 490 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P11714-1", "protein_name": "Cytochrome P450 2D9", "gene_name": "Cyp2d9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELLTGTDLWPVAIFTVIFILLVDLTHQRQRWTSRYPPGPVPWPVLGNLLQVDLGNMPYSLYKLQNRYGDVFSLQMAWKPMVVINGLKAMKEMLLTCGEDTADRPPVPIFEYLGVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEANHLCDAFTAQAGQPINPNPMLNKSTCNVIASLIFARRFEYEDPFLIRMLKVLEQSLTEVSGLIPEVLNAFPILLRIPRLADKALQGQKSFIAILDNLLTENRTTWDPVQAPRNLTDAFLAEIEKAKGNPESSFNDENLLMVVRDLFGAGMLTTSTTLSWALMLMILHPDVQRRVQQEIDEVIGQVRHPEMADQAHMPYTNAVIHEVQRFGDIVPVNLPRITSHDIEVQDFLIPKGTILLPNMSSMLKDESVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSAGRRSCLGEALARMELFLFFTCLLQRFSFSVPDGQPQPSNSGVYGILVAPSPYQLCAVVRDQGH", "length": 504 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P12790-1", "protein_name": "Cytochrome P450 2B9", "gene_name": "Cyp2b9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPSVLLLLAVLLSLFLLLVRGHAKIHGHLPPGPHPLPLLGNLLQMDRGGLLKCFIQLQEKHGDVFTVHLGPRPVVVLCGTQTIREALVDHAEAFSGRGTIAAAQLVMQDYGIFFASGQRWKTLRRFSLATMKEFGMGKRSVEERIKEEAQCLVEELKKYQGVPLDPTFLFQCITANIICSIVFGERFDYTDDQFLHLLNLMYKIFSLLSSFSGQMFELFSGFLKYFPGVHRQIVKKQQELLDYIAHSVEKHKATLDPSAPRDYIDTYLLRMEKEKSNHNTEFHHQNLMMSVLSLFFAGTETTSATLHYGVLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFSDLVPIGLPHKVIKDTLFRGYLLPKNTEVYPVLSSALHDPQYFEQPDKFNPEHFLDANGALKKCEAFLPFSTGKRICLGESIARNELFIFFTTILQNFSVASPVAPKDIDLTPKESGIGKIPPAHQIYFLAR", "length": 491 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P12791-1", "protein_name": "Cytochrome P450 2B10", "gene_name": "Cyp2b10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPSVLLLLALLVGFLLLLARGHPKSRGNFPPGPRPLPLLGNLLQMDRGGLLKSLIQLREKYGDVFTVHLGPRPVVMLCGTDTIREALVGQAEAFSGRGTVAVVEPTFKEYGVIFANGERWKTLRRFSLATMRDFGMGKRSVEERIQEEAQCLVEELRKSQGAPLDPTFLFQCITANVICSIVFGERFEYTDRQFLRLLELFYQTFSLISSFSSQMFELFSGFLKYFPGAHRQISKNLQELLDYIGHSVERHKATLDPSVPRDFIDIYLLRMEKEKSNQNAEFHHQNLMMSVLSLFFVGTETSSTTLHYGFLLMLKYPHVTEKVQKEIDQVIGSHRLPTLDDRTKMPYSDAVIHEIQRFSDLIPIGVPHRVTKDTLFRGYLLPKNTEVYPILSSALHDPQYFEQPDSFNPDQFLDANGALKKSEAFLPFSTGQIFDQKSVGKRICLGESIARSELFLFFTSILQNFSVASHVAPKDIDLTPKESGIGKIPPTYQICFLAR", "length": 500 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P12938-1", "protein_name": "Cytochrome P450 2D3", "gene_name": "Cyp2d3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELLAGTGLWPMAIFTVIFILLVDLMHRRQRWTSRYPPGPVPWPVLGNLLQVDLCNMPYSMYKLQNRYGDVFSLQMGWKPVVVINGLKAVQELLVTCGEDTADRPEMPIFQHIGYGHKAKGVVLAPYGPEWREQRRFSVSTLRNFGVGKKSLEQWVTDEASHLCDALTAEAGRPLDPYTLLNKAVCNVIASLIYARRFDYGDPDFIKVLKILKESMGEQTGLFPEVLNMFPVLLRIPGLADKVFPGQKTFLTMVDNLVTEHKKTWDPDQPPRDLTDAFLAEIEKAKGNPESSFNDANLRLVVNDLFGAGMVTTSITLTWALLLMILHPDVQCRVQQEIDEVIGQVRHPEMADQAHMPFTNAVIHEVQRFADIVPMNLPHKTSRDIEVQGFLIPKGTTLIPNLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPTGQPRPSDYGVFAFLLSPSPYQLCAFKR", "length": 500 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P12939-1", "protein_name": "Cytochrome P450 2D10", "gene_name": "Cyp2d10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELLNGTGLWPMAIFTVIFILLVDLMHRHQRWTSRYPPGPVPWPVLGNLLQVDPSNMPYSMYKLQHRYGDVFSLQMGWKPMVIVNRLKAVQEVLVTHGEDTADRPPVPIFKCLGVKPRSQGVVFASYGPEWREQRRFSVSTLRTFGMGKKSLEEWVTKEAGHLCDAFTAQNGRSINPKAMLNKALCNVIASLIFARRFEYEDPYLIRMLTLVEESLIEVSGFIPEVLNTFPALLRIPGLADKVFQGQKTFMAFLDNLLAENRTTWDPAQPPRNLTDAFLAEVEKAKGNPESSFNDENLRMVVVDLFTAGMVTTATTLTWALLLMILYPDVQRRVQQEIDEVIGQVRCPEMTDQAHMPYTNAVIHEVQRFGDIAPLNLPRITSCDIEVQDFVIPKGTTLIINLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQHFSFSVPAGQPRPSTLGNFAISVAPLPYQLCAAVREQGH", "length": 504 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P13107-1", "protein_name": "Cytochrome P450 2B3", "gene_name": "Cyp2b3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDTSVLLLLAVLLSFLLFLVRGHAKVHGHLPPGPRPLPLLGNLLQMDRGGFRKSFIQLQEKHGDVFTVYFGPRPVVMLCGTQTIREALVDHAEAFSGRGIIAVLQPIMQEYGVSFVNEERWKILRRLFVATMRDFGIGKQSVEDQIKEEAKCLVEELKNHQGVSLDPTFLFQCVTGNIICSIVFGERFDYRDRQFLRLLDLLYRTFSLISSFSSQMFEVYSDFLKYFPGVHREIYKNLKEVLDYIDHSVENHRATLDPNAPRDFIDTFLLHMEKEKLNHYTEFHHWNLMISVLFLFLAGTESTSNTLCYGFLLMLKYPHVAEKVQKEIDQVIGSQRVPTLDDRSKMPYTEAVIHEIQRFSDVSPMGLPCRITKDTLFRGYLLPKNTEVYFILSSALHDPQYFEQPDTFNPEHFLDANGALKKCEAFMPFSIGKRMCLGEGIARSELFLFFTTILQNYSVSSPVDPNTIDMTPKESGLAKVAPVYKICFVAR", "length": 491 }, "evidence": [ { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P15149-1", "protein_name": "Cytochrome P450 2A2", "gene_name": "Cyp2a2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLDTGLLLVVILASLSVMFLVSLWQQKIRERLPPGPTPLPFIGNYLQLNMKDVYSSITQLSERYGPVFTIHLGPRRIVVLYGYDAVKEALVDQAEEFSGRGELPTFNILFKGYGFSLSNVEQAKRIRRFTIATLRDFGVGKRDVQECILEEAGYLIKTLQGTCGAPIDPSIYLSKTVSNVINSIVFGNRFDYEDKEFLSLLEMIDEMNIFAASATGQLYDMFHSVMKYLPGPQQQIIKVTQKLEDFMIEKVRQNHSTLDPNSPRNFIDSFLIRMQEEKYVNSEFHMNNLVMSSLGLLFAGTGSVSSTLYHGFLLLMKHPDVEAKVHEEIERVIGRNRQPQYEDHMKMPYTQAVINEIQRFSNLAPLGIPRRIIKNTTFRGFFLPKGTDVFPIIGSLMTEPKFFPNHKDFNPQHFLDDKGQLKKNAAFLPFSIGKRFCLGDSLAKMELFLLLTTILQNFRFKFPMNLEDINEYPSPIGFTRIIPNYTMSFMPI", "length": 492 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P15392-1", "protein_name": "Cytochrome P450 2A4", "gene_name": "Cyp2a4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLTSGLLLVAAVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFVGNFLQLNTEQMYNSLMKISQRYGPVFTIYLGSRRIVVLCGQETVKEALVDQAEEFSGRGEQATFDWLFKGYGIAFSSGERAKQLRRFSITTLRDFGVGKRGIEERIQEEAGFLIDSFRKTNGAFIDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSLQFTATSMGQVYEMFSSVMKHLPGPQQQAFKELQGLEDFITKKVEHNQRTLDPNSPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKYPDIEAKVHEEIDRVIGRNRQPKYEDRMKMPYTEAVIHEIQRFADLIPMGLARRVTKDTKFRDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFHFKSTQEPQDIDVSPRLVGFVTIPPTYTMSFLSR", "length": 494 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20812-1", "protein_name": "Cytochrome P450 2A3", "gene_name": "Cyp2a3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLASGLLLVASVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFIGNYLQLNTEKMYSSLMKISQRYGPVFTIHLGPRRVVVLCGQEAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSSGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIESFRKTNGALIDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLEDFITKKVEQNQRTLDPNSPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKHPDIEAKVHEEIDRVIGRNRQAKYEDRMKMPYTEAVIHEIQRFADMIPMGLARRVTKDTKFREFLLPKGTEVFPMLGSVLKDPKFFSNPNDFNPKHFLDDKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFCFKSPQAPQDIDVSPRLVGFATIPPNYTMSFLSR", "length": 494 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P20813-1", "protein_name": "Cytochrome P450 2B6", "gene_name": "CYP2B6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELSVLLFLALLTGLLLLLVQRHPNTHDRLPPGPRPLPLLGNLLQMDRRGLLKSFLRFREKYGDVFTVHLGPRPVVMLCGVEAIREALVDKAEAFSGRGKIAMVDPFFRGYGVIFANGNRWKVLRRFSVTTMRDFGMGKRSVEERIQEEAQCLIEELRKSKGALMDPTFLFQSITANIICSIVFGKRFHYQDQEFLKMLNLFYQTFSLISSVFGQLFELFSGFLKYFPGAHRQVYKNLQEINAYIGHSVEKHRETLDPSAPKDLIDTYLLHMEKEKSNAHSEFSHQNLNLNTLSLFFAGTETTSTTLRYGFLLMLKYPHVAERVYREIEQVIGPHRPPELHDRAKMPYTEAVIYEIQRFSDLLPMGVPHIVTQHTSFRGYIIPKDTEVFLILSTALHDPHYFEKPDAFNPDHFLDANGALKKTEAFIPFSLGKRICLGEGIARAELFLFFTTILQNFSMASPVAPEDIDLTPQECGVGKIPPTYQIRFLPR", "length": 491 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P20814-1", "protein_name": "Cytochrome P450 2C13, male-specific", "gene_name": "Cyp2c13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPVVVLLLSLFFLLFLSLWRPSSGRGKLPPGPTPLPIIGNFFQVDMKDIRQSLTNFSKTYGPVYTLYVGSQPTVVLHGYEALKEALVDHGEEFSGRGRLPICEKVAKGQGIAFSHGNVWKATRHFTVKTLRNLGMGKGTIEDKVQEEAKWLVKELKKTNGSPCDPQFIMGCAPGNVICSIILQNRFDYEDKDFLNLIEKVNEAVKIISSPGIQVFNIFPILLDYCPGNHNIYFKNHTWLKSYLLEKIKEHEESLDVSNPRDFIDYFLIERNQENANQWMNYTLEHLAIMVTDLFFAGIETVSSTMRFALLLLMKYPHVTAKVQEEIDHVIGRHRSPCMQDRSHMPYTNAMVHEVQRYIDIGPNGLLHEVTCDTKFRNYFIPKGTAVLTSLTSVLHDSKEFPNPEMFDPGHFLDENGNFKKSDYFIPFSAGKRMCLGESLARMELFLFLTTILQNFKLKSLVDPKDINTTPICSSLSSVPPTFQMRFIPL", "length": 490 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P20852-1", "protein_name": "Cytochrome P450 2A5", "gene_name": "Cyp2a5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLTSGLLLVAAVAFLSVLVLMSVWKQRKLSGKLPPGPTPLPFIGNFLQLNTEQMYNSLMKISQRYGPVFTIYLGPRRIVVLCGQEAVKEALVDQAEEFSGRGEQATFDWLFKGYGVVFSSGERAKQLRRFSIATLRDFGVGKRGIEERIQEEAGFLIDSFRKTNGAFIDPTFYLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSMGQLYEMFSSVMKHLPGPQQQAFKELQGLEDFITKKVEHNQRTLDPNSPRDFIDSFLIRMLEEKKNPNTEFYMKNLVLTTLNLFFAGTETVSTTLRYGFLLLMKHPDIEAKVHEEIDRVIGRNRQPKYEDRMKMPYTEAVIHEIQRFADMIPMGLARRVTKDTKFRDFLLPKGTEVFPMLGSVLKDPKFFSNPKDFNPKHFLDDKGQFKKNDAFVPFSIGKRYCFGEGLARMELFLFLTNIMQNFHFKSTQAPQDIDVSPRLVGFATIPPTYTMSFLSR", "length": 494 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P20853-1", "protein_name": "Cytochrome P450 2A7", "gene_name": "CYP2A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLASGLLLVALLACLTVMVLMSVWQQRKSRGKLPPGPTPLPFIGNYLQLNTEHICDSIMKFSECYGPVFTIHLGPRRVVVLCGHDAVREALVDQAEEFSGRGEQATFDWVFKGYGVAFSNGERAKQLLRFAIATLRDFGVGKRGIEERIQEESGFLIEAIRSTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLSMMLGIFQFTSTSTGQLYEMFSSVMKHLPGPQQQAFKLLQGLEDFIAKKVEHNQRTLDPNSPQDFIDSFLIHMQEEEKNPNTEFYLKNLMMSTLNLFIAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRTKMPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVFPMLGSVLRDPSFFSNPQDFNPQHFLDDKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRLKSSQSPKDIDVSPKHVVFATIPRNYTMSFLPR", "length": 494 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P24456-1", "protein_name": "Cytochrome P450 2D10", "gene_name": "Cyp2d10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELLTGAGLWSVAIFTVIFILLVDLMHRHQRWTSRYPPGPVPWPVLGNLLQVDLDNMPYSLYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWREQRRFSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQPINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMQKVLEDSLTEISGLIPEVLNMFPILLRIPGLPGKVFQGQKSLLAIVENLLTENRNTWDPDQPPRNLTDAFLAEIEKVKGNAESSFNDENLRMVVLDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQVRHPEMADQARMPYTNAVIHEVQRFGDIAPLNLPRITSRDIEVQDFLIPKGSILIPNMSSVLKDETVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQHFSFSVPNGQPRPRNLGVFPFPVAPYPYQLCAVMREQGH", "length": 504 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P24457-1", "protein_name": "Cytochrome P450 2D11", "gene_name": "Cyp2d11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELLTGAGLWSVAIFTVIFILLVDLMHRHQHWTSRCPPGPVPWPVLGNLLQVDLGNMPYSLYKLQNRYGDVFSLQMGWKPMVVINGLKAMKEVLLTCGEDTADRPQVPIFEYLGVKPGSQGVVLAPYGPEWQEQRRFSVSTLRNFGLGKKSLEDWVTKEARHLCDAFTAQAGQSINPNTMLNNAVCNVIASLIFARRFEYEDPYLIRMLKMLKECFTEISGFIPGVLNEFPIFLRIPGLADMVFQGQKSFMAILDNLLTENRTTWDPDQPPRNLTDAFLAEIEKAKGNPESSFNDENLRMVVGDLFTAGMVTTSTTLSWALLLMILHPDVQRRVQQEIDAVIGQVQHPEMADQARMPYTNAVIHEVQRFGDIAPLPLPRITSRDIEVQDFLVTKGSTLIPNMSSVLKDETVWEKPLRFHPEHFLDAQGHFVKPEAFMPFSAGHRSCLGEALARMELFLFFTCLLQRFSISVPDGQPQPSNYRVHAIPVAPFPYQLCAVMREQGH", "length": 504 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P24470-1", "protein_name": "Cytochrome P450 2C23", "gene_name": "Cyp2c23", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELLGFTTLALVVSVTCLSLLSVWTKLRTRGRLPPGPTPLPIIGNLLQLNLKDIPASLSKLAKEYGPVYTLYFGTSPTVVLHGYDVVKEALLQQGDEFLGRGPLPIIEDTHKGYGLIFSNGERWKVMRRFSLMTLRNFGMGKRSLEERVQEEARCLVEELQKTKAQPFDPTFILACAPCNVICSILFNDRFQYNDKTFLNLMDLLNKNFQQVNSVWCQMYNLWPTIIKYLPGKHIEFAKRIDDVKNFILEKVKEHQKSLDPANPRDYIDCFLSKIEEEKDNLKSEFHLENLAVCGSNLFTAGTETTSTTLRFGLLLLMKYPEVQAKVHEELDRVIGRHQPPSMKDKMKLPYTDAVLHEIQRYITLLPSSLPHAVVQDTKFRDYVIPKGTTVLPMLSSVMLDQKEFANPEKFDPGHFLDKNGCFKKTDYFVPFSLGKRACVGESLARMELFLFFTTLLQKFSLKTLVEPKDLDIKPITTGIINLPPPYKLCLVPR", "length": 494 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24903-1", "protein_name": "Cytochrome P450 2F1", "gene_name": "CYP2F1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSISTAILLLLLALVCLLLTLSSRDKGKLPPGPRPLSILGNLLLLCSQDMLTSLTKLSKEYGSMYTVHLGPRRVVVLSGYQAVKEALVDQGEEFSGRGDYPAFFNFTKGNGIAFSSGDRWKVLRQFSIQILRNFGMGKRSIEERILEEGSFLLAELRKTEGEPFDPTFVLSRSVSNIICSVLFGSRFDYDDERLLTIIRLINDNFQIMSSPWGELYDIFPSLLDWVPGPHQRIFQNFKCLRDLIAHSVHDHQASLDPRSPRDFIQCFLTKMAEEKEDPLSHFHMDTLLMTTHNLLFGGTKTVSTTLHHAFLALMKYPKVQARVQEEIDLVVGRARLPALKDRAAMPYTDAVIHEVQRFADIIPMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTPQEFNPEHFLDANQSFKKSPAFMPFSAGRRLCLGESLARMELFLYLTAILQSFSLQPLGAPEDIDLTPLSSGLGNLPRPFQLCLRPR", "length": 491 }, "evidence": [ { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P33261-1", "protein_name": "Cytochrome P450 2C19", "gene_name": "CYP2C19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPFVVLVLCLSCLLLLSIWRQSSGRGKLPPGPTPLPVIGNILQIDIKDVSKSLTNLSKIYGPVFTLYFGLERMVVLHGYEVVKEALIDLGEEFSGRGHFPLAERANRGFGIVFSNGKRWKEIRRFSLMTLRNFGMGKRSIEDRVQEEARCLVEELRKTKASPCDPTFILGCAPCNVICSIIFQKRFDYKDQQFLNLMEKLNENIRIVSTPWIQICNNFPTIIDYFPGTHNKLLKNLAFMESDILEKVKEHQESMDINNPRDFIDCFLIKMEKEKQNQQSEFTIENLVITAADLLGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSPCMQDRGHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPKGTTILTSLTSVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARMELFLFLTFILQNFNLKSLIDPKDLDTTPVVNGFASVPPFYQLCFIPV", "length": 490 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P33267-1", "protein_name": "Cytochrome P450 2F2", "gene_name": "Cyp2f2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGVSTAILLLLLAVISLSLTFSSRGKGQLPPGPKPLPILGNLLQLRSQDLLTSLTKLSKEYGSVFTVYLGSRPVIVLSGYQTVKEALVDKGEEFSGRGAYPVFFNFTRGNGIAFSDGERWKILRRFSVQILRNFGMGKRSIEERILEEGSFLLEVLRKMEGKPFDPVFILSRSVSNIICSVVFGSRFDYDDERLLTIIHFINDNFKIMSSPWGEMYNIFPSVLDWIPGPHKRLFRNFGGMKDLIARSVREHQDSLDPNSPRDFIDCFLTKMAQEKQDPLSHFNMDTLLMTTHNLLFGGTETVGTTLRHAFLILMKYPKVQARVQEEIDRVVGRSRMPTLEDRTSMPYTDAVIHEVQRFADVIPMNLPHRVTRDTPFRGFLIPKGTDVITLLNTVHYDSDQFKTPQEFNPEHFLDDNHSFKKSPAFMPFSAGRRLCLGEPLARMELFIYFTSILQNFTLQPLVDPEDIDLTPLSSGLGNLPRPFQLCMHIR", "length": 491 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P33272-1", "protein_name": "Cytochrome P450 2B12", "gene_name": "Cyp2b12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEFGVLLLLTLTVGFLLFLVSQSQPKTHGHLPPGPRPLPFLGNLLQMNRRGFLNSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFATGERWKTLRRFSLVTMKEFGMGKRSVDERIKEEAQCLVEELKKYKGAPLNPTFLFQSIAANTICSIVFGERFDYKDHQFLHLLDLVYKTSVLMGSLSSQVFELYSGFLKYFPGAHKQIFKNLQEMLNYIGHIVEKHRATLDPSAPRDFIDTYLLRMEKEKSNHHTEFNHQNLVISVLSLFFAGTETTSTTLRCTFLIMLKYPHVAEKVQKEIDQVIGSHRLPTPDDRTKMPYTDAVIHEIQRFADLTPIGLPHRVTKDTVFRGYLLPKNTEVYPILSSALHDPRYFEQPDTFNPEHFLDANGALKKSEAFLPFSTGKRICLGEGIARNELFIFFTAILQNFTLASPVAPEDIDLTPINIGVGKIPSPYQINFLSR", "length": 492 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P33273-1", "protein_name": "Cytochrome P450 2C55", "gene_name": "Cyp2c55", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPVLVLVLTLSCLLLLSLWRQSSGRGKLPPGPTPLPIIGNILQIDVKDISKSFSYFSKIYGPVFTLYFGPKPTVVVHGYEAVKEALDDLGEEFSGRGSFPIVERMNNGLGLIFSNGTKWKELRHFSLMTLRNFGMGKRSIEDRIQEEASCLVEELRKTNGSLCDPTFILSCAPSNVICSVVFHNRFDYKDENFLNLMEKLNENFKILNSPWMQVCNALPAFIDYLPGSHNRVIKNFAEIKSYILRRVKEHQETLDMDNPRDFIDCFLIKMEQEKHNPRTEFTIESLMATVSDVFVAGSETTSTTLRYGLLLLLKHTEVTAKVQEEIDHVIGRHRRPCMQDRTRMPYTDAMVHEIQRYINLIPNNVPHAATCNVRFRNYVIPKGTDLVTSLTSVLHDDKEFPNPEVFDPGHFLDENGNFKKSDYFMPFSTGKRMCVGEALARMELFLLLTTIVQNFNLKSFVDTKDIDTTPMANTFGRVPPSYQLCFIPR", "length": 490 }, "evidence": [ { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P51589-1", "protein_name": "Cytochrome P450 2J2", "gene_name": "CYP2J2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLAAMGSLAAALWAVVHPRTLLLGTVAFLLAADFLKRRRPKNYPPGPWRLPFLGNFFLVDFEQSHLEVQLFVKKYGNLFSLELGDISAVLITGLPLIKEALIHMDQNFGNRPVTPMREHIFKKNGLIMSSGQAWKEQRRFTLTALRNFGLGKKSLEERIQEEAQHLTEAIKEENGQPFDPHFKINNAVSNIICSITFGERFEYQDSWFQQLLKLLDEVTYLEASKTCQLYNVFPWIMKFLPGPHQTLFSNWKKLKLFVSHMIDKHRKDWNPAETRDFIDAYLKEMSKHTGNPTSSFHEENLICSTLDLFFAGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIGQGQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEKLSLKFRMGITISPVSHRLCAVPQV", "length": 502 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P51590-1", "protein_name": "Cytochrome P450 2J3", "gene_name": "Cyp2j3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLVTAGSLLGAIWTVLHLRILLLAAVTFLFLADFLKHRRPKNYPPGPWRLPLVGCLFHLDPKQPHLSLQQFVKKYGNVLSLDFANIPSVVVTGMPLIKEIFTQMEHNFLNRPVTLLRKHLFNKNGLIFSSGQTWKEQRRFALMTLRNFGLGKKSLEQRIQEEAYHLVEAIKDEGGLPFDPHFNINKAVSNIICSVTFGERFEYHDSQFQEMLRLLDEAMCLESSMMCQLYNIFPRILQYLPGSHQTLFSNWRKLKLFISDIIKNHRRDWDPDEPRDFIDAFLKEMAKYPDKTTTSFNEENLICSTLDLFFAGTETTSTTLRWALLCMALYPEVQEKMQAEIDRVIGQGRQPNLADRDSMPYTNAVIHEVQRIGNIIPFNVPREVAVDTYLAGFNLPKGTMILTNLTALHRDPKEWATPDTFNPEHFLENGQFKKRESFLPFSMGKRACLGEQLARSELFIFITSLIQKFTFKPPVNEKLSLQFRMSVTISPVSHRLCAIPRL", "length": 502 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P56593-1", "protein_name": "Cytochrome P450 2A12", "gene_name": "Cyp2a12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGSGLLLLAILAFLSVMVLVSVWQQKIRGKLPPGPIPLPFIGNYLQLNRKDVYSSITQLQEHYGPVFTIHLGPRRVVVLYGYDAVKEALVDHAEEFSGRGEQATFNTLFKGYGVAFSNGERAKQLRRFSIATLRDFGMGKRGVEERIQEEAGCLIKMLQGTCGAPIDPTIYLSKTASNVISSIVFGDRFNYEDKEFLSLLQMMGQVNKFAASPTGQLYDMFHSVMKYLPGPQQQIIKDSHKLEDFMIQKVKQNQSTLDPNSPRDFIDSFLIHMQKEKYVNSEFHMKNLVMTSLNLFFAGSETVSSTLRYGFLLLMKHPDVEAKVHEEIDRVIGRNRQPQYEDHMKMPYTQAVINEIQRFSNFAPLGIPRRITKDTSFRGFFLPKGTEVFPILGSLMTDPKFFSSPKDFNPQHFLDDKGQLKKIPAFLPFSTGKRFCLGDSLAKMELFLFFTTILQNFRFKFPRKLEDINESPTPEGFTRIIPKYTMSFVPI", "length": 492 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56654-1", "protein_name": "Cytochrome P450 2C37", "gene_name": "Cyp2c37", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPILVLVLTLSCLFLLSLWRQSSERGKLPPGPTPLPIIGNILQIDVKDICQSFTNLSKVYGPVYTLYLGRKPTVVLHGYEAVKEALVDHGEEFAGRGRFPVFDKATNGMGLAFSKGNVWKNTRRFSLMTLRNLGMGKRSIEDRVQEEARCLVEELRKTNGSPCDPTFILGCAPCNVICSIIFQDRFDYKDRDFLNLMEKLNEITKILSSPWLQICNTYPALLDYCPGSHKQFFKNYASIKNFLLEKIKEHEESLDVTIPRDFIDYFLINGGQEDGNQPLQNRLEHLAITVTDLFSAGTETTSTTLRYAILLLLKYPHVTAKVQEEIEHVIGKHRSPCMQDRSRMPYTDAMIHEVQRFIDLIPNSLPHEVTSDIKFRNYFIPKGTTVITSLSSVLHDSTEFPNPEKFDPGHFLDENGKFKKSDYFIPFSTGKRICAGEGLARMELFLFLTSILQNFNLKPLVHPKDIDVTPMLIGLASVPPAFQLCFIPS", "length": 490 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56657-1", "protein_name": "Cytochrome P450 2C40", "gene_name": "Cyp2c40", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPFVVLVLCLSFLLVLSLWRQRSARGNLPPGPTPLPIIGNYHLIDMKDIGQCLTNFSKTYGPVFTLYFGSQPIVVLHGYEAIKEALIDHGEEFSGRGRIPVFDKVSTGKGIGFSHGNVWKATRVFTVNTLRNLGMGKRTIENKVQEEAQWLMKELKKTNGSPCDPQFIIGCAPCNVICSIVFQNRFDYKDKDFLSLIGKVNECTEILSSPGCQIFNAVPILIDYCPGSHNKLFKNHTWIKSYLLGKIKEHEESLDVTNPRDFIDYFLIQRRQKNGIEHMDYTIEHLATLVTDLVFGGTETLSSTMRFALLLLMKHTHITAKVQEEIDNVIGRHRSPCMQDRNHMPYTNAMVHEVQRYIDLGPNGVVHEVTCDTKFRNYFIPKGTQVMTSLTSVLHDSTEFPNPEVFDPGHFLDDNGNFKKSDYFVPFSAGKRICVGESLARMELFLFLTTILQNFKLKPLVDPKDIDMTPKHSGFSKIPPNFQMCFIPVE", "length": 491 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q05421-1", "protein_name": "Cytochrome P450 2E1", "gene_name": "Cyp2e1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVLGITVALLVWIATLLLVSIWKQIYRSWNLPPGPFPIPFFGNIFQLDLKDIPKSLTKLAKRFGPVFTLHLGQRRIVVLHGYKAVKEVLLNHKNEFSGRGDIPVFQEYKNKGIIFNNGPTWKDVRRFSLSILRDWGMGKQGNEARIQREAHFLVEELKKTKGQPFDPTFLIGCAPCNVIADILFNKRFDYDDKKCLELMSLFNENFYLLSTPWIQAYNYFSDYLQYLPGSHRKVMKNVSEIRQYTLGKAKEHLKSLDINCPRDVTDCLLIEMEKEKHSQEPMYTMENISVTLADLFFAGTETTSTTLRYGLLILMKYPEIEEKLHEEIDRVIGPSRAPAVRDRMNMPYMDAVVHEIQRFINLVPSNLPHEATRDTVFRGYVIPKGTVVIPTLDSLLFDNYEFPDPETFKPEHFLNENGKFKYSDYFKAFSAGKRVCVGEGLARMELFLLLSAILQHFNLKSLVDPKDIDLSPVTIGFGSIPREFKLCVIPRS", "length": 493 }, "evidence": [ { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q16696-1", "protein_name": "Cytochrome P450 2A13", "gene_name": "CYP2A13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLASGLLLVTLLACLTVMVLMSVWRQRKSRGKLPPGPTPLPFIGNYLQLNTEQMYNSLMKISERYGPVFTIHLGPRRVVVLCGHDAVKEALVDQAEEFSGRGEQATFDWLFKGYGVAFSNGERAKQLRRFSIATLRGFGVGKRGIEERIQEEAGFLIDALRGTHGANIDPTFFLSRTVSNVISSIVFGDRFDYEDKEFLSLLRMMLGSFQFTATSTGQLYEMFSSVMKHLPGPQQQAFKELQGLEDFIAKKVEHNQRTLDPNSPRDFIDSFLIRMQEEEKNPNTEFYLKNLVMTTLNLFFAGTETVSTTLRYGFLLLMKHPEVEAKVHEEIDRVIGKNRQPKFEDRAKMPYTEAVIHEIQRFGDMLPMGLAHRVNKDTKFRDFFLPKGTEVFPMLGSVLRDPRFFSNPRDFNPQHFLDKKGQFKKSDAFVPFSIGKRYCFGEGLARMELFLFFTTIMQNFRFKSPQSPKDIDVSPKHVGFATIPRNYTMSFLPR", "length": 494 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q4V8D1-1", "protein_name": "Cytochrome P450 2U1", "gene_name": "Cyp2u1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSIGGLRPAAGEQPGVGPHLQAVGGALLLCGLAVLLDWVWLQRQRAGGIPPGPKPRPLVGNFGYLLLPRFLRLHFWLGSGSQTDTVGRHVYLARLARVYGNIFSFFIGHRLVVVLSDFQSVREALVQQAEVFSDRPRMPLISILTKEKGIVFAHYGPIWKQQRRFSHSTLRHFGLGKLSLEPRIIEEFAYVKAEMQKHGEAPFSPFPVISNAVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINLCPWFYYLPFGPFKELRQIERDITCFLKNIIKEHQESLDANNPQDFIDMYLLHTQEEKDKCKGTNFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPGVQKKVHEEIERVIGRDRAPSLTDKAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGYSIPKGTVVLPNLWSIHRDPVIWEKPDDFCPHRFLDDQGQLLKRETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFTFALPEGSEKPIMTGRFGLTLAPHPFNVTVSKR", "length": 530 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64458-1", "protein_name": "Cytochrome P450 2C29", "gene_name": "Cyp2c29", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLVVFLALTLSCLILLSLWRQSSGRGKLPPGPTPLPIIGNFLQIDVKNISQSFTNFSKAYGPVFTLYLGSKPTVILHGYEAVKEALIDRGEEFAGRGSFPMAEKIIKGFGVVFSNGNRWKEMRRFTLMTLRNLGMGKRNIEDRVQEEAQCLVEELRKTKGSPCDPTFILSCAPCNVICSIIFQNRFDYKDKEFLILMDKINENVKILSSPWLQVCNSFPSLIDYCPGSHHKIVKNFNYLKSYLLEKIKEHKESLDVTNPRDFIDYYLIKQKQVNHIEQSEFSLENLASTINDLFGAGTETTSTTLRYALLLLLKYPDVTAKVQEEIDRVVGRHRSPCMQDRSHMPYTDAMIHEVQRFIDLLPTSLPHAVTCDIKFRKYLIPKGTTVITSLSSVLHDSKEFPNPEMFDPGHFLNGNGNFKKSDYFMPFSTGKRICAGEGLARMELFLILTTILQNFKLKSLVHPKEIDITPVMNGFASLPPPYQLCFIPL", "length": 490 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q64583-1", "protein_name": "Cytochrome P450 2B15", "gene_name": "Cyp2b15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELGVLLLLTFTVGFLLLLASQNRPKTHGHLPPGPRPLPFLGNLLQMNRRGLLRSFMQLQEKYGDVFTVHLGPRPVVILCGTDTIREALVDQAEAFSGRGTVAVLHPVVQGYGVIFANGERWKILRRFSLVTMRNFGMGKRSVEERIKEEAQCLVEELKKYKGALLNPTSIFQSIAANIICSIVFGERFDYKDHQFLRLLDLIYQTFSLMGSLSSQVFELFSGFLKYFPGVHKQISKNLQEILNYIDHSVEKHRATLDPNTPRDFINTYLLRMEKEKSNHHTEFHHQNLVISVLSLFFTGTETTSTTLRYSFLIMLKYPHVAEKVQKEIDQVIGSHRLPTLDDRTKMPYTDAVIHEIQRFADLIPIGLPHRVTNDTMFLGYLLPKNTEVYPILSSALHDPRYFDHPDTFNPEHFLDVNGTLKKSEAFLPFSTGKRICLGEGIAQNELFIFFTAILQNFSLASPVAPEDIDLSPINSGISKIPSPYQIHFLSRCVG", "length": 495 }, "evidence": [ { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q64680-1", "protein_name": "Cytochrome P450 2D4", "gene_name": "Cyp2d4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRMPTGSELWPIAIFTIIFLLLVDLMHRRQRWTSRYPPGPVPWPVLGNLLQIDFQNMPAGFQKLRCRFGDLFSLQLAFESVVVLNGLPALREALVKYSEDTADRPPLHFNDQSGFGPRSQGVVLARYGPAWRQQRRFSVSTFRHFGLGKKSLEQWVTEEARCLCAAFADHSGFPFSPNTLLDKAVCNVIASLLFACRFEYNDPRFIRLLDLLKDTLEEESGFLPMLLNVFPMLLHIPGLLGKVFSGKKAFVAMLDELLTEHKVTWDPAQPPRDLTDAFLAEVEKAKGNPESSFNDENLRVVVADLFMAGMVTTSTTLTWALLFMILRPDVQCRVQQEIDEVIGQVRRPEMADQARMPFTNAVIHEVQRFADILPLGVPHKTSRDIEVQGFLIPKGTTLIINLSSVLKDETVWEKPLRFHPEHFLDAQGNFVKHEAFMPFSAGRRACLGEPLARMELFLFFTCLLQRFSFSVPAGQPRPSNYGVFGALTTPRPYQLCASPR", "length": 500 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6VVW9-1", "protein_name": "Vitamin D 25-hydroxylase", "gene_name": "Cyp2r1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLELPGARACAGALAGALLLLLFVLVVRQLLRQRRPAGFPPGPPRLPFVGNICSLALSADLPHVYMRKQSRVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWIDHRRLAVNSFHYFGSGQKSFESKILEETWSLIDAIETYKGGPFDLKQLITNAVSNITNLILFGERFTYEDTDFQHMIELFSENVELAASAPVFLYNAFPWIGILPFGKHQRLFRNADVVYDFLSRLIEKAAVNRKPHLPHHFVDAYLDEMDQGQNDPLSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVHKEIDLIVGHNRRPSWEYKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWKDPDMFYPERFLDSNGYFTKKEALIPFSLGRRHCLGEQLARMEMFLFFTSLLQQFHLHFPHELVPNLKPRLGMTLQPQPYLICAERR", "length": 501 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6VVX0-1", "protein_name": "Vitamin D 25-hydroxylase", "gene_name": "CYP2R1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWKLWRAEEGAAALGGALFLLLFALGVRQLLKQRRPMGFPPGPPGLPFIGNIYSLAASSELPHVYMRKQSQVYGEIFSLDLGGISTVVLNGYDVVKECLVHQSEIFADRPCLPLFMKMTKMGGLLNSRYGRGWVDHRRLAVNSFRYFGYGQKSFESKILEETKFFNDAIETYKGRPFDFKQLITNAVSNITNLIIFGERFTYEDTDFQHMIELFSENVELAASASVFLYNAFPWIGILPFGKHQQLFRNAAVVYDFLSRLIEKASVNRKPQLPQHFVDAYLDEMDQGKNDPSSTFSKENLIFSVGELIIAGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPNGKPSWDDKCKMPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHELVPDLKPRLGMTLQPQPYLICAERR", "length": 501 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7Z449-1", "protein_name": "Cytochrome P450 2U1", "gene_name": "CYP2U1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSPGPSQPPAEDPPWPARLLRAPLGLLRLDPSGGALLLCGLVALLGWSWLRRRRARGIPPGPTPWPLVGNFGHVLLPPFLRRRSWLSSRTRAAGIDPSVIGPQVLLAHLARVYGSIFSFFIGHYLVVVLSDFHSVREALVQQAEVFSDRPRVPLISIVTKEKGVVFAHYGPVWRQQRKFSHSTLRHFGLGKLSLEPKIIEEFKYVKAEMQKHGEDPFCPFSIISNAVSNIICSLCFGQRFDYTNSEFKKMLGFMSRGLEICLNSQVLLVNICPWLYYLPFGPFKELRQIEKDITSFLKKIIKDHQESLDRENPQDFIDMYLLHMEEERKNNSNSSFDEEYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKAQMPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKPEDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDSKKPLLTGRFGLTLAPHPFNITISRR", "length": 544 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CIM7-1", "protein_name": "Cytochrome P450 2D26", "gene_name": "Cyp2d26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLVGDDLWAVVIFTAIFLLLVDLVHRRQRWTACYPPGPVPFPGLGNLLQVDFENIPYSFYKLQNRYGNVFSLQMAWKPVVVVNGLKAVRELLVTYGEDTSDRPLMPIYNHIGYGHKSKGVILAPYGPEWREQRRFSVSTLRDFGLGKKSLEQWVTEEAGHLCDAFTKEAEHPFNPSPLLSKAVSNVIASLIYARRFEYEDPFFNRMLKTLKESLGEDTGFVGEVLNAIPMLLHIPGLPDKAFPKLNSFIALVNKMLIEHDLTWDPAQPPRDLTDAFLAEVEKAKGNPESSFNDKNLRIVVIDLFMAGMVTTSTTLSWALLLMILHPDVQRRVHQEIDEVIGHVRHPEMADQARMPYTNAVIHEVQRFADIVPTNLPHMTSRDIKFQDFFIPKGTTLIPNLSSVLKDETVWEKPLRFYPEHFLDAQGHFVKHEAFMPFSAGRRSCLGEPLARMELFLFFTCLLQRFSFSVPDGQPRPSDYGIYTMPVTPEPYQLCAVAR", "length": 500 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TAV3-1", "protein_name": "Cytochrome P450 2W1", "gene_name": "CYP2W1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLLLLFLGLLGLWGLLCACAQDPSPAARWPPGPRPLPLVGNLHLLRLSQQDRSLMELSERYGPVFTVHLGRQKTVVLTGFEAVKEALAGPGQELADRPPIAIFQLIQRGGGIFFSSGARWRAARQFTVRALHSLGVGREPVADKILQELKCLSGQLDGYRGRPFPLALLGWAPSNITFALLFGRRFDYRDPVFVSLLGLIDEVMVLLGSPGLQLFNVYPWLGALLQLHRPVLRKIEEVRAILRTLLEARRPHVCPGDPVCSYVDALIQQGQGDDPEGLFAEANAVACTLDMVMAGTETTSATLQWAALLMGRHPDVQGRVQEELDRVLGPGRTPRLEDQQALPYTSAVLHEVQRFITLLPHVPRCTAADTQLGGFLLPKGTPVIPLLTSVLLDETQWQTPGQFNPGHFLDANGHFVKREAFLPFSAGRRVCVGERLARTELFLLFAGLLQRYRLLPPPGVSPASLDTTPARAFTMRPRAQALCAVPRP", "length": 490 }, "evidence": [ { "id": "HGNC:20243", "url": "https://alliancegenome.org/gene/HGNC:20243#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091113-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-17#orthology", "database": "AGR" }, { "id": "MGI:3616076", "url": "https://alliancegenome.org/gene/MGI:3616076#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91W64-1", "protein_name": "Cytochrome P450 2C70", "gene_name": "Cyp2c70", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALFIFLGIWLSCFLFLFLWNQHRGRGKLPPGPTPLPIVGNILQVDVKNISKSMGMLAKKYGPVFTVYLGMKPTVVLHGYKAMKEALIDQGDEFSDKTDSSLLSRTSQGLGIVFSNGETWKQTRRFSLMVLRSMGMGKKTIEDRIQEEILYMLDALRKTNGSPCDPSFLLACVPCNVISTVIFQHRFDYNDQTFQDFMENFHRKIEILASPWSQLCSAYPILYYLPGIHNRFLKDVTQQKKFILEEINRHQKSLDLSNPQDFIDYFLIKMEKEKHNQKSEFTMDNLVVSIGDLFGAGTETTSSTVKYGLLLLLKYPEVTAKIQEEIAHVIGRHRRPTMQDRNHMPYTDAVLHEIQRYIDFVPIPSPRKTTQDVEFRGYHIPKGTSVMACLTSVLNDDKEFPNPEKFDPGHFLDEKGNFKKSDYFVAFSAGRRACIGEGLARMEMFLILTNILQHFTLKPLVKPEDIDTKPVQTGLLHVPPPFELCFIPV", "length": 489 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q95078-1", "protein_name": "Cytochrome P450 18a1", "gene_name": "Cyp18a1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLADSYLIKFVLRQLQVQQDGDAQHLLMVFLGLLALVTLLQWLVRNYRELRKLPPGPWGLPVIGYLLFMGSEKHTRFMELAKQYGSLFSTRLGSQLTVVMSDYKMIRECFRREEFTGRPDTPFMQTLNGYGIINSTGKLWKDQRRFLHDKLRQFGMTYMGNGKQQMQKRIMTEVHEFIGHLHASDGQPVDMSPVISVAVSNVICSLMMSTRFSIDDPKFRRFNFLIEEGMRLFGEIHTVDYIPTMQCFPSISTAKNKIAQNRAEMQRFYQDVIDDHKRSFDPNNIRDLVDFYLCEIEKAKAEGTDAELFDGKNHEEQLVQVIIDLFSAGMETIKTTLLWINVFMLRNPKEMRRVQDELDQVVGRHRLPTIEDLQYLPITESTILESMRRSSIVPLATTHSPTRDVELNGYTIPAGSHVIPLINSVHMDPNLWEKPEEFRPSRFIDTEGKVRKPEYFIPFGVGRRMCLGDVLARMELFLFFASFMHCFDIALPEGQPLPSLKGNVGATITPESFKVCLKRRPLGPTAADPHHMRNVGAN", "length": 538 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-091113-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-17#orthology", "database": "AGR" }, { "id": "RGD:1564244", "url": "https://alliancegenome.org/gene/RGD:1564244#orthology", "database": "AGR" }, { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q96SQ9-1", "protein_name": "Cytochrome P450 2S1", "gene_name": "CYP2S1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEATGTWALLLALALLLLLTLALSGTRARGHLPPGPTPLPLLGNLLQLRPGALYSGLMRLSKKYGPVFTIYLGPWRPVVVLVGQEAVREALGGQAEEFSGRGTVAMLEGTFDGHGVFFSNGERWRQLRKFTMLALRDLGMGKREGEELIQAEARCLVETFQGTEGRPFDPSLLLAQATSNVVCSLLFGLRFSYEDKEFQAVVRAAGGTLLGVSSQGGQTYEMFSWFLRPLPGPHKQLLHHVSTLAAFTVRQVQQHQGNLDASGPARDLVDAFLLKMAQEEQNPGTEFTNKNMLMTVIYLLFAGTMTVSTTVGYTLLLLMKYPHVQKWVREELNRELGAGQAPSLGDRTRLPYTDAVLHEAQRLLALVPMGIPRTLMRTTRFRGYTLPQGTEVFPLLGSILHDPNIFKHPEEFNPDRFLDADGRFRKHEAFLPFSLGKRVCLGEGLAKAELFLFFTTILQAFSLESPCPPDTLSLKPTVSGLFNIPPAFQLQVRPTDLHSTTQTR", "length": 504 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CX98-1", "protein_name": "Cytochrome P450 2U1", "gene_name": "Cyp2u1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLGDQRPAAGEQPGARLHVRATGGALLLCLLAVLLGWVWLRRQRACGIPPGPKPRPLVGNFGHLLVPRFLRPQFWLGSGSQTDTVGQHVYLARMARVYGNIFSFFIGHRLVVVLSDFHSVREALVQQAEVFSDRPRMPLISIMTKEKGIVFAHYGPIWKQQRRFSHSTLRHFGLGKLSLEPRIIEEFAYVKEAMQKHGEAPFSPFPIISNAVSNIICSLCFGQRFDYTNKEFKKVLDFMSRGLEICLHSQLFLINICPWFYYLPFGPFKELRQIERDISCFLKNIIREHQESLDASNPQDFIDMYLLHMEEEQGASRRSSFDEDYLFYIIGDLFIAGTDTTTNSLLWCLLYMSLNPDVQKKVHEEIERVIGCDRAPSLTDKAQMPYTEATIMEVQRLSMVVPLAIPHMTSEKTVLQGFTIPKGTVVLINLWSVHRDPAIWEKPDDFCPHRFLDDQGQLLKRETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQTFTFALPEGSEKPVMTGRFGLTLAPHPFNVTISKR", "length": 530 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DBX6-1", "protein_name": "Cytochrome P450 2S1", "gene_name": "Cyp2s1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAASTWALLLALLLLLLLLSLTLFRTPARGYLPPGPTPLPLLGNLLQLRPGALYSGLLRLSKKYGPVFTVYLGPWRRVVVLVGHDAVREALGGQAEEFSGRGTLATLDKTFDGHGVFFANGERWKQLRKFTLLALRDLGMGKREGEELIQAEVQSLVEAFQKTEGRPFNPSMLLAQATSNVVCSLVFGIRLPYDDKEFQAVIQAASGTLLGISSPWGQAYEMFSWLLQPLPGPHTQLQHHLGTLAAFTIQQVQKHQGRFQTSGPARDVVDAFLLKMAQEKQDPGTEFTEKNLLMTVTYLLFAGTMTIGATIRYALLLLLRYPQVQQRVREELIQELGPGRAPSLSDRVRLPYTDAVLHEAQRLLALVPMGMPHTITRTTCFRGYTLPKGTEVFPLIGSILHDPAVFQNPGEFHPGRFLDEDGRLRKHEAFLPYSLGKRVCLGEGLARAELWLFFTSILQAFSLETPCPPGDLSLKPAISGLFNIPPDFQLRVWPTGDQSR", "length": 501 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V399-1", "protein_name": "Probable cytochrome P450 303a1", "gene_name": "Cyp303a1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFYTVIWIFCATLLAILFGGVRKPKRFPPGPAWYPIVGSALQVSQLRCRLGMFCKVIDVFARQYVNPYGFYGLKIGKDKVVIAYTNDAISEMMTNEDIDGRPDGIFYRLRTFNSRLGVLLTDGEMWVEQRRFILRHLKNFGFARSGMMDIVHNEATCLLQDLKDKVLKSGGKQTRIEMHDLTSVYVLNTLWCMLSGRRYEPGSPEITQLLETFFELFKNIDMVGALFSHFPLLRFIAPNFSGYNGFVESHRSLYTFMSKEIELHRLTYKNYDEPRDLMDSYLRAQDEGNDEKGMFSDQSLLAICLDMFLAGSETTNKSLGFCFMHLVLQPEIQERAFQEIKEVVGLERIPEWSRDRTKLPYCEAITLEAVRMFMLHTFGIPHRAVCDTRLSGYEIPKDTMVIACFRGMLINPVDFPDPESFNPDRYLFDGHLKLPEAFNPFGFGRHRCMGDLLGRQNLFMFTTTVLQNFKMVAIPGQVPEEVPLEGATAAVKPYDIMLVAREQ", "length": 503 }, "evidence": [ { "id": "HGNC:20243", "url": "https://alliancegenome.org/gene/HGNC:20243#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VWR5-1", "protein_name": "Cytochrome P450 306a1", "gene_name": "phtm", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSADIVDIGHTGWMPSVQSLSILLVPGALVLVILYLCERQCNDLMGAPPPGPWGLPFLGYLPFLDARAPHKSLQKLAKRYGGIFELKMGRVPTVVLSDAALVRDFFRRDVMTGRAPLYLTHGIMGGFGIICAQEDIWRHARRETIDWLKALGMTRRPGELRARLERRIARGVDECVRLFDTEAKKSCASEVNPLPALHHSLGNIINDLVFGITYKRDDPDWLYLQRLQEEGVKLIGVSGVVNFLPWLRHLPANVRNIRFLLEGKAKTHAIYDRIVEACGQRLKEKQKVFKELQEQKRLQRQLEKEQLRQSKEADPSQEQSEADEDDEESDEEDTYEPECILEHFLAVRDTDSQLYCDDQLRHLLADLFGAGVDTSLATLRWFLLYLAREQRCQRRLHELLLPLGPSPTLEELEPLAYLRACISETMRIRSVVPLGIPHGCKENFVVGDYFIKGGSMIVCSEWAIHMDPVAFPEPEEFRPERFLTADGAYQAPPQFIPFSSGYRMCPGEEMARMILTLFTGRILRRFHLELPSGTEVDMAGESGITLTPTPHMLRFTKLPAVEMRHAPDGAVVQD", "length": 574 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-091113-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091113-17#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "S4R196-1", "protein_name": "unspecific monooxygenase", "gene_name": "Cyp2ab1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLFSGMAFLAGSCLLLKLATLCWRRSHLPPGPFPFPLLGNLWQLNFQLHPNMLFQLAQTHGSVFTVWLGSTPIVVLSGFRAVKEALVSNSEQFSGRPLTPFFRDLFGEKGVICSNGLTWRQQRRFCLTTLRELGLGKQALEVQLQHEAAELAKVFLQEEGRAFDPQIPIIRSTTRVIGTLVFGHHFLSEEPIFLELIQAINLGLAFASTIWRRLYDMFPWALRHLSGPHQKIFQYHEAVRGFIRHEIIRHKLRTAEAPKDFINCYLSQITKAIDDPVSTFSEENLIQVVIDLFLGGTDTTATTLHWALIYLVHHRAIQERVQQELDEMLGAAQTICYEDRERLPYTRAVLHEVQRLSSVVAVGAVRQCVTSTWMHGYYVPKGTIILPNLASVLYDPECWESPHQFNPGHFLDKDGNFVANEAFLPFSAGHRVCPGEQLARMELFLMFATLLRTFQFQLPEGSQDLGLEYVFGGTLQPQPQKICAVLRQSSLSPREP", "length": 498 }, "evidence": [ { "id": "FB:FBgn0010383", "url": "https://alliancegenome.org/gene/FB:FBgn0010383#orthology", "database": "AGR" }, { "id": "FB:FBgn0004959", "url": "https://alliancegenome.org/gene/FB:FBgn0004959#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "iron ion binding", "id": "GO:0005506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005506", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVB4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4" } ], "pmid": "" }, { "name": "heme binding", "id": "GO:0020037", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0020037", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVB4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen", "id": "GO:0016712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016712", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVB4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVB4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVB4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "xenobiotic metabolic process", "id": "GO:0006805", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006805", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVB4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4" } ], "pmid": "" }, { "name": "organic acid metabolic process", "id": "GO:0006082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006082", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVB4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVB4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVE5-1", "uniprot_ac": "A0A8N7UVE5", "uniprot_id": "A0A8N7UVE5_DANRE", "mass": { "chemical_mass": 63389.0, "monoisotopic_mass": 63389.0 }, "refseq": { "ac": "XP_700123", "name": "E3 ubiquitin/ISG15 ligase TRIM25", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700123" }, "gene_names": [ { "name": "ftr13", "type": "recommended", "evidence": [ { "id": "A0A8N7UVE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5" } ] }, { "name": "ftr13", "type": "synonym", "evidence": [ { "id": "XP_700123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700123" } ] } ], "protein_names": [ { "name": "E3 ubiquitin/ISG15 ligase TRIM25", "type": "synonym", "evidence": [ { "id": "XP_700123", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700123" }, { "id": "A0A8N7UVE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_700123.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_700123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700123" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVE5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ftr13", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-395", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-395", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVE5", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UVE5", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19769", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19769", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "571442", "url": "https://www.ncbi.nlm.nih.gov/gene/571442", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:571442", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571442", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UVE5", "url": "https://www.orthodb.org/?gene=A0A8N7UVE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_700123", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_700123", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVE5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-395", "url": "https://zfin.org/ZDB-GENE-070912-395", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAECSISVAQDQFSCSICLDLLKDPVAIPCGHSYCMSCISDCWDQDEQRGVYSCPQCRQTFTPRPALGKNTMLAEVVGKLKKTKLQAARPAQCYSESADVECDVCTGDKNKAVKSCLMCLNSYCQNHLEQHASFFRSKKHNLMDATGRLQEMICPQHDKLLEVFCRTDQCCICYLCTMDGHKNHNTVSAAAERTDKHRQLEETQSKLHQRIQRKQVEFEELRAAVESHKCSAQAAVEDTERIFTDLIRSIERSRSEVTQLIRDQEKAAVSEAEGRLERLEQEIDDLRRRDAELEQLSHTDHHIHFLQSFQSLSTPPGSTDSSSITVSSSLSFDDVGKSVSRLREKLEHFCREEIEKITWRMRDYKGTTPTPEPKTHQEFLQYTCWLFLDLNTMNKNLVLSKGNRVIELSSTVQQYPDHPDRFDCWHQVLCRESVCGRCYWEVEWSGSVGISVAYKSIGWKGQGTEFGYSNQSWCLFCSGSICTFVHKSKHTVLPLVSSSSRIGVYVDHSAGTLSFYSVSDTMSLIHRVHTTFTQPLYPGFELVSYNPCGSKLKLCEL", "length": 557, "header": "tr|A0A8N7UVE5-1|A0A8N7UVE5_DANRE Isoform 1 of E3 ubiquitin/ISG15 ligase TRIM25 OS=Danio rerio OX=7955 GN=ftr13 PE=4 SV=1 CANONICAL=A0A8N7UVE5-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5/entry#A0A8N7UVE5-1", "sequence": { "sequence": "MAECSISVAQDQFSCSICLDLLKDPVAIPCGHSYCMSCISDCWDQDEQRGVYSCPQCRQTFTPRPALGKNTMLAEVVGKLKKTKLQAARPAQCYSESADVECDVCTGDKNKAVKSCLMCLNSYCQNHLEQHASFFRSKKHNLMDATGRLQEMICPQHDKLLEVFCRTDQCCICYLCTMDGHKNHNTVSAAAERTDKHRQLEETQSKLHQRIQRKQVEFEELRAAVESHKCSAQAAVEDTERIFTDLIRSIERSRSEVTQLIRDQEKAAVSEAEGRLERLEQEIDDLRRRDAELEQLSHTDHHIHFLQSFQSLSTPPGSTDSSSITVSSSLSFDDVGKSVSRLREKLEHFCREEIEKITWRMRDYKGTTPTPEPKTHQEFLQYTCWLFLDLNTMNKNLVLSKGNRVIELSSTVQQYPDHPDRFDCWHQVLCRESVCGRCYWEVEWSGSVGISVAYKSIGWKGQGTEFGYSNQSWCLFCSGSICTFVHKSKHTVLPLVSSSSRIGVYVDHSAGTLSFYSVSDTMSLIHRVHTTFTQPLYPGFELVSYNPCGSKLKLCEL", "length": 557, "header": "tr|A0A8N7UVE5-1|A0A8N7UVE5_DANRE Isoform 1 of E3 ubiquitin/ISG15 ligase TRIM25 OS=Danio rerio OX=7955 GN=ftr13 PE=4 SV=1 CANONICAL=A0A8N7UVE5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 370, "start_aa": "Thr", "end_pos": 370, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr370", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:571442", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571442", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1REU8-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr65", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEFSVSVAQDQFSCAVCLDLLNDPVSIPCGHSYCMSCITDCWNKKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQEIHPGNQHQLTEATHRLKEMICPQHEKLLEIFCRTDHCCICYLCLVDQHKHHDTVSAAAERTELESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSITVSFPLDFDDIVKSVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTVNNWLVLSEGNTAVENKGSVQPYPDHPDRFDYWRQVLCRESVCGRSYWELEWSGARVFLSVSYKSIKRKGRGNECLFGRNAQSWSLSCSAESFSFRHNNKNTELPKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTNTLCPGFYVYKGSKVKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RFB3-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr14l", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRSSTASQSRYGTQEKPRRSGRYSSSSSRSSSRDVLCDFCMIKKNKAVKSCLTCLTSFCEAHLQAHYEYPALMKHKLVAATGQLREKICGEHDKLLEVFCRSDQMCVCVLCIMEEHKKHDIVSAAAERTEKQKQLGAKLMTSQQKIEERMKKWQDLRQAVASLKHSSQSVLDENERIFAELLRALERRHGEVKEMIRAQEVLLLTNAERHLARLEEEITLLRKKHTDLEQLSQSDDHIHFLQSWQSLSAPSGYEDLSKVTLAPHHTFDNAKKAISDLKVQMEDISKEELNKISSAVNEVKILQTVDPAKREEFFEYSCQLSIDPLTAHPNLVLSDRNTVVQMSNEPRPYPDHPDRFDYWQQALCKPGLAGGRYYWELDWRGTEVDIAVTYKGIQRKGNDKPGSFGRNDKSWSLYCSESEYSFMHNSKSTAVSVPRSSRIGVYVDYESGTLAFYSVSDKMTLLYKVQTKFTEPLYPGIGVWGYGTTVRL", "length": 489 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RJY4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr03", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSDSSKMAAESSVSFAQDQFNCSICLDLLKDPVAIPCGHSYCMSCISDYWDQDEWRGVYSCPQCRQTFTPRPALGKNTMLTEVVENIRKRKLQAGDVECDVCIGKAVKSCLVCLESYCQTHFEQHEEFHSRKRHKVTDANGRLQEMICPQHDRLLEMYCRTDQRCICMLCLMNEHKTHETVLPAEERAEKQKHFNEKLQQRIQEKQKQCEELRAAVESHKRSVQAAVEDTERIFTELIRSIERSRSKVTQLIRDQGKASVSGAEGRLEQLEQEINDLRRRNTELEQLSCTDNDIHFLQSFQSLSVPPASTDSSSISSRLSFNKFKMFVSRVKEELQNSLKDEKENISRIVRNISVLPTPEYERRKKFLQYYQQLTLDSNTAYKSLRLSEGNRVVTRMKKTSNHPDRFDGFAQLLCKESVRGRCYWEVERSGKGMYVSVSYKSIRRKGQGSECKFGCNDQSWSLYCSDTKCSFRHNNEESKLPVVSSSSRIGVYVDHSAGTLSFYSVSDTMSLIHRVHTTFTQPLYPGFGVSNESQVKLCDQA", "length": 542 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RKP5-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr76", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSESSSSECVDQFSCSVCLDLLKEPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCRESFSQRPLLKKNTLIAEMMETLQKTTLQTPAAAATAVDCDVCTTEKNRAVKSCLQCLASFCQTHLQLHYESPAFMKHKLVDASRHIQENICPSHGRPLEIYCQDDHQCICCLCIINSHKTHSVVSVDSEWINKKKELEKIAVERLKLIENREKGLWELSEAVKSFKSSADEAVEKMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIHKLLTTEDQIHCLKSCESVCVLPTFEEVPFSPHSHLSFKDLSISAFREALEDACRQQTDAISREVSNVHTVKPSEPKTYNDFLQYFYQPHLDPNTAHKNLILSEENRRISYSDTDQQYPDHPERFAAYCNVLCKEGLTGRCYWEVNCHGKIWAVAVCYKGISRKGNTDDNILGYNKQSWRLSRYQKNIFFVHNSEEVSIPVFHSSRIGVYLDHRAGILSFYSVSKTMTLIHKVQTTFTELLYPAFGLGECSIRIIKQKRFLKDQK", "length": 553 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RLP4-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25 isoform X1", "gene_name": "ftr02", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAQDQFNCSICLDLLKDPVAIPCGHSYCMCCISGYWDQDEQKGVYSCPQCRQTFTPRPALGKNTMLVEVVEKLRKRKLQAARPAQCYSESADVECDVCTGDKNKATKSCLMCLNSYCQNHLEQHETFFKIKRHNLMDATGRLQEMICPQHEKLLGIFCRTDKRCICYLCTMDEHKTHDTVSAAAERTDKQKYFEETLKKRIMENQKEREELRAALESHKRSVQATVEDTERIFTELICSIERTRSEVTQVIRDQEKAAVSGAERRLKKLEQEIDDLKRRNTELEQISNTDNHIHFLQNFQSFSVPPESTDTSIRSRLSFDDLVTFVSQVKEKLQQTVKQEQKNIFHIVRHINVMPSPQNKSRNDFLQYYKRFTLASNTAHESLKLSEGNRVVTRAKNALFSFPDIFEDLTQVLCNESVSGCCYWEVEWSGRGMCASVAYKSISRKGPGYDCRFGHNDQSWGLYFSDFSCSFWHNNIHTKLPGVSSSSRIGVYVDHSTGTLSFYSVSGRMRLIHRVYTTFTQPLYPGFGVCHDSQLKLCD", "length": 546 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RLR7-1", "protein_name": "Tripartite motif-containing protein 16 isoform X1", "gene_name": "ftr33", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSKMAESSVSLAHREFSCSVCLDLLKDPVAIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQQLNPGNRHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISRRVSSISIIPAPEPQTREQFLQYSQQFTLDPNTAHTYLVLSEGNTAVENKGSVQPYPDHPDRFDCWRQVLCRESVCGRSYWELEWSGVDVLISVSYKSISRKGSGNECLFGLNDQSWSLCCSADSFSFRHNNINTDLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFWVCSRLKLCDLTV", "length": 561 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RN91-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr36", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFCPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQELNPGNQHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTELESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTANNRLILSEGNTVVDCKGSVQPYPDHPDRFDGWFQVLCKESVCRRSYWELEWSGNGVEIAVSYKSISRKGSILECRFGLNDQSWSLFCSVHSFSFWHNNKQTQLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHALYPGLCLYSRVKLCDLTV", "length": 556 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2B8U3-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr57", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEVRFSLEEFMCPVCLDLLKDPVTIPCGHSYCKTCITGCWDQEDDKRVYSCSQCREAFNPRPALAKNTILAEMVEKLKTKPPADCYAGAGDVQCDVCTGIKYKAIKSCLVCQESYCRTHFDRHEEFHSRKPHKVIDATERLQDMICRKHEKELEMYCITDQMCICLMCKEYEHKNHETMSTAAQRTEKQKELKETQMKLQQRVQQRQKDLQQLREAVESQKRCAQTAVEDTDRIFTEIIRLIERRRSELTQMIRDQQKTAVSEAEGLMKRLEKEIDHLRRRGAELEQLSHTQDHIHFLQSFQSLSAPPESTDVSFNPLLSFDDLKESVQQLKVKLEDFCKEEIRKTSDKGTPILNDPFKDTFANIVPKTTRDFLKYYSRFTLDLNTVNKYLCLSSNMITYTNTPQPYPDHPDRFDQLCQVLCRESVSGRCYWEIKWSGYGVCISVSYKGIRRKGQGKDCIFGGNDQSWCLFCYPGDYSFIHNDLKTVLPVQSISSRVGVYVDHSAGILSFYSVSNTMTLIHKVQTTFTQPLYPGFNVNGYKSSVILC", "length": 548 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAS0-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr26", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSTSVVEDQFSCSICKDLLREPVTIPCGHSYCMICITDCWSQDEQRRVYSCPQCRQTFTPRPALNKNVVMAEMVENLKKTGLKSRANYAEAGDVKCDVCAGRKRKAVKSCLLCLNSYCETHFECHEVFHSSKRHKVTDATGRIQEMICSQHDRLLEVYCRTDQKCVCLMCVMDEHKNHDTVSAEAERAEKQIQVGETQTQLQNRIQEKQSKLQQLRESVEIHKSSAQTAVDDCERIFTEIIRCIKRRRLKVTQMIRDREKTEVSRAEGLLKKVEQEIEDLKRRNTELEQLSHTDDHIHFLQSLQPLIIPAESTDSMTVSSLPSYEDVGKSVSELRKKLDDFCKEQIKLISASVSCRTQILPTTKPKTREDFLKYFHQFTLDSQSVHNNLSLSDENRVATFTASMHAYPDHPDRFDTWPQVLCRENVCGRCYWEVEWSGNHGVAIAVSYKSISRKGQGTECKFGYNDQSWRLFCSASGYIFSHNNRKRDLPVVSKIGVYVDQRAGVLSFFRVSDTKMSLIHRVQTTFTQPLYPGFGLNRDSSVKLSSMI", "length": 551 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAU1-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr34", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNQHKVTEATHKLQEMICPQHEKPLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTEQESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFFISSQLSFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISIIPAPEAQTHEQFLQYSQQFTLDPNTAHNRLVLSEGNTAVENNWSVQPYPDHPDRFDGYSQVLCRESVCGRSYWELEWSGNGVEISVSYKSISRKGSGNECLFGRNDQSWSLCCSPLSLSFYHNNINTKLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFYVNYSSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BAX9-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr35", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCSVCLDLLKDPVSIPCGHNYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNRHKVTEATHKLQEMICPQHEKPLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTEQESRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEIEMISSRVSSISIITAPEPQTREQFLQYSQQFTLDPNTAHKYLVLSEGNTAVEDKDSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGDGVYLSVSYKSISRKGSGNECGFGHNDQSWSLCCSDYSFSFRHNNIKTKLPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLMHTLHTTFTHTLYPGFCVYYSSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AQJ4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr95", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSLSLAHHFSCAVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHQGNRHKVTEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCLLDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTAYNRLVLSEGNTAVENKRSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGEDVEISVSYKSISRKGLGNECVFGFNDQSWSLSCSAHSFIFYHNNIKTDLRKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFRVYVCSRLKLCDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B808-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr29", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAHHEFSCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFCPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHQGNRHKVTEATHKLQEMICPQHEKLLEIFCRTDHCCICYLCLVDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSPLVFDDIAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEPQTREQFLQYSQQFTLDPNTAYNRLVLSEGNTAVENKRSVQPYPDHPDRFDGWRQVLCRESVCGRSYWELEWSGEDVEISVSYKSISRKGSGNECVFGFNDQSWSLSCSAHSFIFYHNNIKTDLRKPSVSCSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFRVYVCSRLKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YUU8-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSVAHREFSCAVCLDLLKDPVSTACGHNYCMSCITNCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEMVEKLRKSKLQAAGPAQSPAASGDVECDVCSGAKNRAVKSCLVCLNSYCHTHFQLHQQLNPGNQHKVTEATHRLKKLICPQHEKPLEIFCRTDHCCICYLCTMDQHKNHNTVSAVAERTEQQRRLKNIQSSFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLSFNKVTESVSRLRDKLQQFCTEEMKTISSRVSSISIIPAPEPQTREQFLQYSQQFTLDPNTAHTYLVLSEGNTAVENKGSVQPYPDHPDRFDCWHQVLCRESVCGRSYWELEWSGVDVLISVSYKSISRKGSGNECLFGLNDQSWSLCCSADSFSFYHNNIKTDLPKPSVSSSRRGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFCVYYSSRLKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YW98-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEAGISWSQNQFSCSICLDLLKGPVTIPCGHSYCMRCISGYWDQDKQRGVYICPQCRQTFTPRPALGKNTMLAEVVEQLKKTKLQAARPAHCYSESADVECDVCTGDKNKAVKSCLVCLNSYCQNHLEQHESFFRGKRHNLMDATGRLQEMICPQHDKLLEVFCRTDQCCICLLCVDEHKNHEIVSATAERTDKQRQLEETQSKHNQRIQRKQEECVELRVAIESQKCSAQAAVEDTERIFTDLIRSIERRRSEVTQLIRDQEKAQVSAAEGRLERLKQEIDDLRRRDAELEQLSHTDHHIHFLQSFQSLSTPPGSTDSSSITVSSSLSFDDVGKSVSRLREKLEDFCREEIEKISVRGITSIQKPELKTREDFLQYYRPLTLDPNTVNNCLVLSEGNRVFEHTSTNQQYPDHPDRFDCFLQVLCRENVYGRCYWEVEWSGDVEILVAYKSISRKGLGDECGFGRNDQSWGLSCSRSRCSFCHNKKQTKLPVMSNSSRIGVYVDHSAGTLSFYSISNTMSLIHRVHTTFTQPLYPGFGIDSLYSLFSETKQKIKLSDLKI", "length": 561 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6Z1N9-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25 isoform X1", "gene_name": "ftr73", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCLHVADCFEASAKMSESSSSEYVDQFSCPVCLDLLKEPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCRESFSQRPLLKKNTLIAEMMETLQKTALQTPAAAAVDCDVCTTEKNRAVKSCLQCLASFCQTHLQLHYESPAFMKHKLVDASRHIQENICPSHGRPLEIYCQDDHQCICCMCTDNHKGHSVVSVDSEWTSKKEELEEMKLKCLKLIKDREKGQQDLSKATKNLKSSADEAVERMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFKDVPSFTSHTHLSFKDLSISAFREALEDACQQQTDAISREVSNVHVVQTPQPKSEHDFLQYYCKLQMDSSTAHRELKLSEEKRKVSFSDEVQPYPDHPQRFDWFHYILCREGLTGRCYWEVECSGDIWGVAVCYRGIRRKGNSDDCKLGFNKVSWRLNRLQQNITYIRNKVQVRIKAGCFSRIGVYLDHRAGILSFYSVSDTNTLLYKVQTTFTEPLYPAFIIGQGSSVRIFDKRTAQMEELT", "length": 567 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PAX6-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEGRFSVDQNKFDCPICLDLLKEPVTIPCGHSYCMNCITDCWSQDEQRRVYSCPQCRQTFTPRPALNKNVVMAEMVENLKVTKVKTTDPAPSYAGPGDVECDVCTGIKYKAIKSCLLCLESYCQTHFERHEAFRTGKRHKITDASGRIQEMICLKHDKLLEVYCRTDQKCICLLCTMDEHKNHDTVSSSSERTEKQKHLEDTQRNLQQKIQEREKKIQVLKESLKTHKSSAQTAVEDSERTFTELIQSIERRRSEVTQMIRDREKTEVSLTEGLLKKLEQEIEDMKRRNTELEQLLHTDDHIHFLQRFQSLSKPLESTDLSSTAVSSGFRYEDVSKSVSQLKIKLEQICTEDIENIHGQARKMIFSALLSTSHTEPTTRKDFQQYFQQLSLDQNTAHQQICLTEDNTVATWTDRVQQYPDHPDRFDKFFGVLCRESVSGRCYWEVEWSGNERLYGVGVAVSYKTINRKGDMTTSGFGFNDQSWRLFSFKSRYTFLHDSKQTELSVVSRSSRIGVYVDHRAGILSFFSVSDTTMSLIHRVQTTFTQPLYPGFWINKGSRVKICHI", "length": 565 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PJ13-1", "protein_name": "Tripartite motif-containing protein 16 isoform X1", "gene_name": "ftr11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVCLAQEQFSCSICLDLLKDPVAIPCGHSYCMSCISDCWDQDERKGVYSCPQCRQTFTPRPALGKNTMLTEVMENIRKRKLQAGDVECDVCTGRKFKAVKSCLVCLESYCQTHFQHHEEFHSRKRHKVTDATGRLQEMICPQHEKLLEIFCRTDQCCICYLCTMDKHKNHDTVSAAAEWTDKKIQLAEMQKTTHQRMVERQKEREELRAAVESHKRSAQAAVEDTESIFTELIFSFERSCSEVTQLITDQQKAAEGRAEERLKQLEQEINDLRRRNTELEQLSHTDHHIHFLKSFQSLSSPPGSTDSSSITVSSRISFDDVGKLSHLRKKLEQFCREEIEKISSKVRDINIISISAEPKTRQEFLQYSRQLTFDPNTVNTSLVLSKKNRVIEYTDKVQQYPDHPDRFDCWPQVLCRESECGRFYWEVEWNGYIEISVSYKSISRKGRGNECVFGCNDQSWSLFCSRSRFSFRHNKQQTKLPVLSISSRIGVYVDHSAGTLSFYNVSDTMSLIYRVHTTFTQPLYPGFWVFAGSILFTTDTL", "length": 545 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PRK9-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr41", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEVRISVDQIEFMCPVCLDLLKDPVTLHCGHSYCKSCITDFWDQEYEKRIYSCPQCRQSFTPRPALAKNTMLAEVVEKLKKTKPPADCCAGAGDVQCDACTGRKYKAVKSCLQCQESYCQTHFERHEEFHSRKPHKVIDATGQLRDMICQKHGKELEIYCITDQQCICELCKEYEHKNHATVSTAEQMTEKQQELKERQVKLQQREKALRKLKNAVESQKRSAQTAVEDTEKIFTELIHSIQKKGTELTQVISSAEKTAVSQAEEHMEYLEQEIEDLRRRNAELERLSQTQEHVNFLQRFQSLPAPLESTDGYFSSFLCFDAMKESVHELKSKLENLCKEEIKMILDRVTSFVPKTRNDFLQYSIKLTLDLHTAHKCLSKKRKVVTCTKKEQPYPDHPDRFHDWPQVLCTERVRGRRYWEVEWSGDKGVCISASYKSISRTGTGNECAFGGNDHSWSLFCSPLRYLFWHNNIQSDLTVKPNSHKIGVYVNVGAGTLSFYNVSDEMSLIHTFQTTFTQPLFPGFTVGFGSSVKLKHR", "length": 537 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6I4-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr94", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAEARFSQDEFLCPVCLELLKDPVSLHCGHNYCKGCISGFWDQEDEKRVYSCPQCRQTFSQRPALAKNTMLAEVVEKLKKTKPPADCKAGAGDVQCDVCTGTKYKAIKSCLQCQESYCQTHFENHEEFHFRKSHKVIDATGQLQDMICQKHKKELEIYCITDQQCICELCKEFEHTTHETLSVAEQRKEKQKELKETQVKLQESLQQRQQELQQLREAVESHKRSAQTAVKDTERIFTELICSIEKRCSELTQIIRDQEKTAVSRAEGHMEWLEQEVENLRRRNAELEQLSHKKDHVQFLKSFQSFSAPPESTDVLSSSLLCFDGLSESVSQLKDKLEDFCKKELKKISDRVTKTSPKTRNDFLQYSHQFTLDLNTMNDHLRLSESNRVITGAETAQPTFDHPDKFNGWPQVLCRESVRGRCYWEIEWSGDVGVILSVSYKSISRKGFGNECAFGGNDKSWSLACFPTRYSFWHNSKRTDLSVKPISRMIGVYVDESAGILSFYGISNTISLIHTVKTTFTQPLYPGFTVDPRSSVKLC", "length": 539 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TBM3-1", "protein_name": "Tripartite motif-containing protein 16", "gene_name": "ftr37", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSVAHHEFSCAVCLDLLKDPVSTACGHNYCMSCITNCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQRHQEIHPGNQHKVTEATHKLKKLICPQHEKPLEIFCRTDQLCICYLCTMDQHKNHNTVSAVAERTEQQRRLKNIQSSFQQRLQERQKELEKLKKAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSPLVFDDIAESVSHLREDLEHFGKKEIKLISRRVSSISRIPAPVPKTREQFLQYSQQFTLDPNTVNNWLVLSERNTVVKYKGSVQRYPDHPDRFNCWYQVLCRESVCGRSYWELEWSGVDVYLSVSYKSISRKGSGNECLFGYNDHSWSLWCSADSFIFYHNNKQTKLPKPSVSSTRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHALYPGFCVHYSSRVKLCDLTV", "length": 559 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UV20-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X1", "gene_name": "ftr91", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESMLSQQKDQFSCSVCLDPLKQPVTIPCGHSYCMSCITDCWSLKEQGPPYRCPQCREIFRQKPLLKKNTLIAEMMETLQKTALQTPAAAVDCDVCTTEKNRAVKSCLQCWASFCQTHLQLHYKSPAFMNHKLVEASRHICPNHKKPQDIYCQDDHQCICYLCMIDSHKGHRVVSVEAELINKKNKLKEMKLKCQTLIKERQRGWQELSIAMKLFKSSADEAVEKMEKVFTELICSLEKKRSEIKEQIRAQEKTETDRAEQLHQHLHQELTQLRKTQAEIDKLLTTEDQIHCLKSCESVCVLPTFEDVPSFTSHTHLSFKDLSFSAFREALEDACQQQTDAISREVSNIHVVKPPDLKTQNDFLQYFCQIHLDRNTAHKNLKVTEDNKKVSCSDKDQKYPDHPERFDGYCHVLCREGLTGRCYWEVECSGKYWAVAVCYRGISRKGVSDDCKLGFNKISWRLGYYLQNFSFIHGKAHVRLPPASRIGVYLDHKAGMLSFYSVSDTMTLLHRVQTTFTEPLYPAFYSGSGSSVKIIE", "length": 537 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UV86-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25", "gene_name": "ftr38", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESSVSLAHCKFSCSECLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKLQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQELNPGNQHKVIEATHRLKEMICQQHKKLLEIFCRTDHCCICSLCVLDGHKNHDTVSAAAQRTKKQCRLKKTQSRFQQRLQERQKELEELREAVESHKHSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSFQSLSVPPGSTDSSSFFISSQLSFNKVTESVSRLSDKLQQFCTEEMKTISDKVRFISIIPAPEPQTREQFLQYSQQFTLDPNTVNKKLVLSEGNTAVEINGSDQPYPDHPDRFDGFSQVLCKESVCGRSYWELECSSASVYLSVSYKSISRKGSGNECRFGNNDQSWSLFCSDNSFSFWHNNIKTDLRKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFYVYLAKVKICDLTV", "length": 558 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58GXY0-1", "protein_name": "FinTRIM family, member 23 isoform X1", "gene_name": "ftr23", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGFSETGKCSPTLLSEMAESSISVAEDQFSCSVCLDLLKEPVTIPCGHSYCMNCITDCWNQDEQRRVYSCPQCRQTFTPRPALNKNVVMVEMVEKLKTGSRNAASYAGPGDVECDVCTGRKRKAVKSCLMCLSSYCQTHLEQHDSFFKDKRHHLINATGRLRQMICSKHDRLLEVYCHTDQKCICLLCMMDEHTGHQTVSIKTERAEKQKQLLDLQKNFQKTIQEREEEVWDLKHAVKTHKHSAQTAVEESERIFTRLFHFIERRQSEVSQMIRDRKKTEVSRAEGLLKKLEEEIEDLKRRNTELEQLSHTDDHIHFLQSFHSLSAPPESPESSDVTSLLFYDDVGETLSVLKEKLEDACKEATENMSVLETPYMEIVSTSELINRDKFLQYFHHLTLDSNTAHKYLRLSEGNRVATFIGADQSYPAHPDRFHDFSQVLCRESVCGRCYWEVEWSGEAGVGISVSYKSIRRKGEGFDCVFGFNDQSWRLSCSNSRYTLRHKQLSTKLRVPSGSNRIGVYVDHKAGILSFFNISDTMSLIHRVQTTFTQPLYPGFGINFGSTVKLKSAENL", "length": 570 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58I1B9-1", "protein_name": "E3 ubiquitin/ISG15 ligase TRIM25-like isoform X2", "gene_name": "ftr30", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTHTGSVRAERNRKFTQIPCSVCLDLLKDPVSIPCGHSYCMSCITDCWNQEDQKRVYSCPQCRQTFSPRPALAKNTMLAEVLEKQQKSKLQAAGPAQSPAASGDVECDVCTGAKNRAVKSCLVCLNSYCHTHFQLHQQLNPGNQHKVIEATHKLQEMICPQHKKLLEIFCRTDHCCICYLCMVDQHKHHDTVSAAAERTELQSRLRETQSRFQQRLQERQKELEELREAVESHKRSAQAAVDHTERIFTQLICWIERSRSELTQMIRDGEKTAVSGAEERLERLEQEINDLRRRNAELEQLSHTEDHIHFLQSLQSLSVPPGSTDSSSFISSSQLAFDQLAESVSRLRDKLQQFCTEEMKTISSRVSSISRIPAPEAQTREQFLQYSQQFTLDPNTVNNCLVLSEGNTAVDYKDSVQPYPDHPDRFDCSYQVFCRESVCGRSYWELEWSGVVYLSVSYKSISRKGRNIECGFGNNDQSWSLECSPYSFSFWHNKIKTALPKPSVSSSRIGVYVDHSAGTLSFYSVSDTTMSLIHTLHTTFTHTLYPGFGVYSSRLKLCDLTV", "length": 562 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ACD6B7A1-1", "protein_name": "LOW QUALITY PROTEIN: tripartite motif-containing protein 16", "gene_name": "ftr42", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAETRFSQDEFLCPVCLDLLKDPVAIHCGHSYCKSCITDFWNMEDEKGIYSCPQCRQTFSPRPALAKNTMLAEVVDKLKKTTPPADCYAGAEDVQCDACTGTKYKAIKSCLQCLESYCQTHFERHEEFHSRKPHKVIDATGRLQDMICPKHEKELEVYCITDQQCICELCKEYEHKNHKTVSAAAQRTEKQKELKETLVKLQERLQQRQKDLQQLRAAVESHKQSAQTAVEDTDRIFTELIYSIEKRRSELTQMIRDQEKTTRSRAERHMEQLEQEIEDLRRRNTELEQLSHTHHHIHFLQSFQSLSAPPESTDVSFSSLLCFDGLRESVSQLKVKLEDFCIEEIEKFTERVTKTVPKTRNDFLQYSHKLTLDLNTAHKLLHLSERNRIIICTETEQPYPDHPDRFDSWRQVLCRESVRGRCYWEIEWSGIKGVCISVSYKSISRKGFGNECVFGGNDQSWGLFCSTSRYSLWHNKKRSDLPLKPISRRIGVYVDVGAGTLSFYSIFDTMSLIHTVQTTFTQPIYPGFTVDPRSSVKLC", "length": 539 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LMT9-1", "protein_name": "Tripartite motif protein 80", "gene_name": "Trim80", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSAKLGSFLRKGHLDRETMKQQPQRTVRRRRSPVHRAAKYLAVIDMQKISRPTQDKSPSELSTQSSRTSLQLLMSSNSSQHLLEDQVLCPICLDVFRNPVTTACGHNFCMTCLQSFWDHQADTGETYYCPQCREAFPSRPRLCKNVILGEMVACFTLAKSQTSGPLWGLAGPTDVPCDFCSPQKLKATKSCLQCMASLCEKHLHSHFEDPLFQEHQLLDPVWDLKNRLCRKHRKLRQMYCRTEGSCVCGACLLEEHQNHDTTPLEDERARKEVEVRKIQANVENQMLIIASDSQKHQGRVSFLSKLIQTMREEVNTCFSEILHEVKQLQMKVLDFVENEETVALGMLGNSMQQSHSRLLKLEGDSVWLHGLLANKSDEQFLQEFPTLKHFPACVEPLLGTNCEETQSFLQLPETLAQLRIRLMDIGLNFINQLLLKGIRMNSYEVLPATVDRKTLLQNYCNLNFDSSMASEELFLFKETHSVLNLGILLEPSTTSPLPGFKQWPQVLCCPGLSEGCHYWETEVSDSWMCLGVTYRRNPSMSGRHRRNIVYLLGRNPYSWCLEWDSLKFSVWHNNTQTVLHGSYHHTLGVALDFRAGCLSFYGVAGDVSLLYRFLTSFLEPLYPAVMVSSGASLTLKQYPEA", "length": 642 }, "evidence": [ { "id": "RGD:1311352", "url": "https://alliancegenome.org/gene/RGD:1311352#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-395", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-395#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVE5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVE5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5" } ], "pmid": "" }, { "name": "ligase activity", "id": "GO:0016874", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016874", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVE5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVE5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 470, "end_pos": 472, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UVE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 149, "end_pos": 189, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UVE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 366, "end_pos": 557, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UVE5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVE5" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 58, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 370 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 470, "end_pos": 472 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVF1-1", "uniprot_ac": "A0A8N7UVF1", "uniprot_id": "A0A8N7UVF1_DANRE", "mass": { "chemical_mass": 114009.0, "monoisotopic_mass": 114009.0 }, "refseq": { "ac": "XP_694162", "name": "GEM-interacting protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694162" }, "gene_names": [ { "name": "gmip", "type": "recommended", "evidence": [ { "id": "A0A8N7UVF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1" } ] }, { "name": "gmip", "type": "synonym", "evidence": [ { "id": "XP_694162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694162" } ] } ], "protein_names": [ { "name": "GEM-interacting protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_694162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694162" }, { "id": "A0A8N7UVF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_694162.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_694162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694162" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVF1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gmip", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-823", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-823", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVF1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UVF1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd04378", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04378", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd20816", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20816", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "565801", "url": "https://www.ncbi.nlm.nih.gov/gene/565801", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046349", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046349", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051025", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051025", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVF1", "url": "https://www.orthodb.org/?gene=A0A8N7UVF1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15228:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15228:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22699", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22699", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_694162", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694162", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVF1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J3T6", "url": "https://www.uniprot.org/uniprotkb/A0AC58J3T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J3T6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J3T6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-823", "url": "https://zfin.org/ZDB-GENE-130530-823", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEETVETAQLRQPKDGDIPVRHSETKRYSEILRDFDALDLSLKCSTVDELLQEADSLSLPDTSADTTLNADLDDITGEDVEDEVKICREEEEKDEGTLSIAQDADLSLCHCEDGVELALQYAKMWCRYAKDLLTWMDKRISLEQEFAKSIMRAADAAKSCVAQQDMMPLQNIYTQALEHDLKTSASAKQSAENIQQRCYQALSAKRNEIDKWRREFKEQWSKEQKRMHDAVSALKRARQQYMQRCEELEKAKAMTAKAEEDTGGYKTLDKRRKSRDDAQTKVTETEMQYRQCVSEANNHQKELDKVKRKIIVHIRKLICQGDTVLKEATMKMFNFQRQQTEPVPLAYQNLQLTCAPCEPGEPYLHYILGKRLPDQPPQIYIFQEFIPQNRRSPPTGRRKQSNIQQDLYALPDDLKHSSSLVDGRRPGQSDRDSTGSLESLSSPAHGTRKLPKASSTGTMSSDDLDEKDPEESEEGLSDSNGMTCKPRSASRAALTHRLRKMKSKMVKCKQCDNYILVNGIECEECGLAVHRKCLEVCQLECEHRRGFVFGTEFSSLPRETQDSVPFVVLRCTEEIENRALGVQGVYRISGSKPRVLKLCQAFEIQKDQVDLSDLSPHDITSVLKHFFKELPEPLLTFDLYNDFIAVGKEIQRLSEKDHAAESPGIVENIVRRLRELIGRLPVCNNITVQHMMAHLNRVAEQFEDNKMSPGNLGIVFGPTLLRPLVSGDVSMIALLETSYQALLVEFMISNYDQVFGSATRSGTPPPPPPTAPLPETPPRATCPVSPSSSSSQDPTATSRERPRSLENRTIKRDSSEGYISDKSSSNEAMDQLSPEANERAVLAMSATASPQGLPGQAAENQLQTRSRTHLSRQPVKYYRQGSAGAQSRKTSAQLRDENISVSGEGLVSGSADSSRSSSPEPLKTLLCLQETVVPQDKTESQTGAHAGVQRTVSQESVQAGASSFVREGNTNQSNNTLRGRERLIRSLRRRSVEEKTSQKVLSGLRLNSGKGEQLHFV", "length": 1017, "header": "tr|A0A8N7UVF1-1|A0A8N7UVF1_DANRE Isoform 1 of GEM-interacting protein isoform X1 OS=Danio rerio OX=7955 GN=gmip PE=4 SV=1 CANONICAL=A0A8N7UVF1-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVF1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1/entry#A0A8N7UVF1-1", "sequence": { "sequence": "MEETVETAQLRQPKDGDIPVRHSETKRYSEILRDFDALDLSLKCSTVDELLQEADSLSLPDTSADTTLNADLDDITGEDVEDEVKICREEEEKDEGTLSIAQDADLSLCHCEDGVELALQYAKMWCRYAKDLLTWMDKRISLEQEFAKSIMRAADAAKSCVAQQDMMPLQNIYTQALEHDLKTSASAKQSAENIQQRCYQALSAKRNEIDKWRREFKEQWSKEQKRMHDAVSALKRARQQYMQRCEELEKAKAMTAKAEEDTGGYKTLDKRRKSRDDAQTKVTETEMQYRQCVSEANNHQKELDKVKRKIIVHIRKLICQGDTVLKEATMKMFNFQRQQTEPVPLAYQNLQLTCAPCEPGEPYLHYILGKRLPDQPPQIYIFQEFIPQNRRSPPTGRRKQSNIQQDLYALPDDLKHSSSLVDGRRPGQSDRDSTGSLESLSSPAHGTRKLPKASSTGTMSSDDLDEKDPEESEEGLSDSNGMTCKPRSASRAALTHRLRKMKSKMVKCKQCDNYILVNGIECEECGLAVHRKCLEVCQLECEHRRGFVFGTEFSSLPRETQDSVPFVVLRCTEEIENRALGVQGVYRISGSKPRVLKLCQAFEIQKDQVDLSDLSPHDITSVLKHFFKELPEPLLTFDLYNDFIAVGKEIQRLSEKDHAAESPGIVENIVRRLRELIGRLPVCNNITVQHMMAHLNRVAEQFEDNKMSPGNLGIVFGPTLLRPLVSGDVSMIALLETSYQALLVEFMISNYDQVFGSATRSGTPPPPPPTAPLPETPPRATCPVSPSSSSSQDPTATSRERPRSLENRTIKRDSSEGYISDKSSSNEAMDQLSPEANERAVLAMSATASPQGLPGQAAENQLQTRSRTHLSRQPVKYYRQGSAGAQSRKTSAQLRDENISVSGEGLVSGSADSSRSSSPEPLKTLLCLQETVVPQDKTESQTGAHAGVQRTVSQESVQAGASSFVREGNTNQSNNTLRGRERLIRSLRRRSVEEKTSQKVLSGLRLNSGKGEQLHFV", "length": 1017, "header": "tr|A0A8N7UVF1-1|A0A8N7UVF1_DANRE Isoform 1 of GEM-interacting protein isoform X1 OS=Danio rerio OX=7955 GN=gmip PE=4 SV=1 CANONICAL=A0A8N7UVF1-1" }, "locus": {} }, { "isoform_ac": "A0AC58J3T6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1/entry#A0AC58J3T6-1", "sequence": { "sequence": "MEETVETAQLRQPKDGDIPVRHSETKRYSEILRDFDALDLSLKCSTVDELLQEADSLSLPDTSADTTLNADLDDITGEDVEDEVKICREEEEKDEGTLSIAQDADLSLCHCEDGVELALQYAKMWCRYAKDLLTWMDKRISLEQEFAKSIMRAADAAKSCVAQQDMMPLQNIYTQALEHDLKTSASAKQSAENIQQRCYQALSAKRNEIDKWRREFKEQWSKEQKRMHDAVSALKRARQQYMQRCEELEKAKAMTAKAEEDTGGYKTLDKRRKSRDDAQTKVTETEMQYRQCVSEANNHQKELDKVKRKIIVHIRKLICQGDTVLKEATMKMFNFQRQQTEPVPLAYQNLQLTCAPCEPGEPYLHYILGKRLPDQPPQIYIFQEFIPQNRRSPPTGRRKQSNIQQDLYALPDDLKHSSSLVDGRRPGQSDRDSTGSLESLSSPAHGTRKLPKASSTGTMSSDDLDEKDPEESEEGLSDSNGMTCKPRSASRAALTHRLRKMKSKMVKCKQCDNYILVNGIECEECGLAVHRKCLEVCQLECEHRRGFVFGTEFSSLPRETQDSVPFVVLRCTEEIENRALGVQGVYRISGSKPRVLKLCQAFEIQKDQVDLSDLSPHDITSVLKHFFKELPEPLLTFDLYNDFIAVGKEIQRLSEKDHAAESPGIVENIVRRLRELIGRLPVCNNITVQHMMAHLNRVAEQFEDNKMSPGNLGIVFGPTLLRPLVSGDVSMIALLETSYQALLVEFMISNYDQVFGSATRSGTPPPPPPTAPLPETPPRATCPVSPSSSSSQDPTATSRERPRSLENRTIKRDSSEGYISDKSSSNEAMDQLSPEANERAVLAMSATASPQGLPGQAAENQLQTRSRTHLSRQPVKYYRQGSAGAQSRKTSAQLRDENISETVVPQDKTESQTGAHAGVQRTVSQESVQAGASSFVREGNTNQSNNTLRGRERLIRSLRRRSVEEKTSQKVLSGLRLNSGKGEQLHFV", "length": 988, "header": "tr|A0AC58J3T6-1|A0AC58J3T6_DANRE Computationally mapped isoform of GEM-interacting protein isoform X2 OS=Danio rerio OX=7955 GN=gmip PE=4 SV=1 CANONICAL=A0A8N7UVF1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 770, "start_aa": "Thr", "end_pos": 770, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr770", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A2AB59-1", "protein_name": "Rho GTPase-activating protein 27", "gene_name": "Arhgap27", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADVEGDVYVLVEHPFEYTGKDGRRIAIQPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPAPAPQPSVPQQRPAVPEPLAYDYRFVSTPVGADGSSAEPRGRASSLCGPARQRTGGQRNSLAPGGPACLYVRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASSVAGSWVCPRPLAPSDSENVYEAIPDLRCPPRAESPKQVDDPPEPVYANVERQPRATSPRSAAAPPRLSPVWETHTDTGTGRPYYYNPDTGVTTWESPFETPEGTTSPATSRASVGSGESLETEWGQYWDEESRRVFFYNPLTGETAWEDETEELEEDHQEQLEMQPSLSPRSPGQQRPPTPETDYPELLASYPEEDYSPVGSFSDPGPASPLVAPPGWSCQITPDKQMLYTNQFTQEQWVRLEDQHGKPYFYNPEDSSVQWELPQVPIPAPRSVRKSSQDSDTPAQASPPEEKIKTLDKAGVLHRTKTVDKGKRLRKKHWSTSWTVLEGGVLTFFKDSKTSAAGGLRQPSKLSTPEYTVELKGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGISELSADLLQGEEGEPSSADFGSSERLGSWREEDVRQNAASPSLSPGGLESDLSRVRHKLRKFLQRRPTLQSLRDKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRSRCVRDLVRTLPAPNQDTLRLLIQHLCRVIEHGEQNRMTVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH", "length": 869 }, "evidence": [ { "id": "SGD:S000000464", "url": "https://alliancegenome.org/gene/SGD:S000000464#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZA46-1", "protein_name": "Gem-interacting protein", "gene_name": "Gmip", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSTETELTPAPEGRKRYSDIFQSLDNLEISLGNVTFDPLAGDLVLREDLEPDKTDTAAVETEENSEASWSNPSPEGPAPLTEEELDLRLIRTKGGVDAALEYAKAWSRYAKELLAWTDKRANYELEFAKNIMKIAEAGKGSILQQSQMPLQYIYTLFLEHDHSLGALAIDTVAQQKRDYYQPLAAKRMEIEKWRKEFKEQWLKEQKRMSEAEQALRRSQLQYIQRREDLRARTQGSPEDPPLQASPGSNKQQERRRRSREEAQAKAHEAEALYQACVREANTRQQDLETTKRRIVSHVRKLVLQGDEVLRRVTLGLFELRGAQAERGPRSFSALAECCVPFEPGQRYQEFVRSLQPGAPPPPSPAFCFQEFAPVVHSFPQDTKKKFSGPLPTRLEEGPSEPGPWEVASLGSQGIPGSDVDSVGGGSESRSLDSPTSSPGAGARRLVKASSTGTESSDDFEERDPDLGDGMENGTGSPFRKWTLSTAAQTHRLRRLRGPAKCRECEAFMVSGTECEECFLTCHKRCLETLLILCGHQRLPARMPLFGVDFLQLPRDFPEEVPFVVTRCTAEIEHRALGLQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDITSVLKRFLQELTDPVVPFHFYDAFISLAKTLHADPGDDPGTPSPSPEIIRSLKTLLVQLPDSNYSTLRHLVAHLFRVAARFKENKMSANNLGIVFGPTLLRPPDGPGATSASPVACLLDSGHQAQLVEFLIVHYEQIFGMDELPLTSEPLTQDPALAPALLESSPQHPALLVAQDSQPLTIASDSSPDPKQHSALEKCPKVAPPELTALQSNRKEEEEEDTRDGAGDGSSHSPEDLLLVAQSRGHFSRQPVKYSRGGVRPVTHQLSSLALVASKLCEETPITVSAVHRGSLRARGLGPAAASPEGGTLRRNPLPKHFEITQETARLLSKLDSEAVSRTSCCADPEPEESEEHL", "length": 969 }, "evidence": [ { "id": "HGNC:24852", "url": "https://alliancegenome.org/gene/HGNC:24852#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-823", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-823#orthology", "database": "AGR" }, { "id": "MGI:1926066", "url": "https://alliancegenome.org/gene/MGI:1926066#orthology", "database": "AGR" }, { "id": "RGD:1565577", "url": "https://alliancegenome.org/gene/RGD:1565577#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZDI5-1", "protein_name": "Rho GTPase-activating protein 12", "gene_name": "Arhgap12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAERSGKIASGQVYIEVEYDYEYEAKDRKIVIRQGERYLLVKKTNDDWWQVRLDENSKAFYVPAQYVKEVTRKALMPPVKQTTGLPNNSMKTTQSMHLQRSTENVNKMPELSSFGKPSSSVQGTGLIRDANQNFGSNYNSGQTLNLSLDLTHNNGKFNSDSHSPKVSSQNRTRLFGHFPGPEFLDIEKTSFSQEQSCDSAGEGSERTHQDSESGDELSSSSTEQMRATTPPNQGRPDSPVYANLQELKISQSALPPLPGSPAIQVNGEWETHKDSSGRCYYYNRTTQERTWKPPRWARDVSTSRDFQSPGEQEPLSSEENYHSSCFSQSDSQCGSPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDSNDKDSPTSTKLCLPENESPPTSTKHQDPGQEKYGLLNVTKITENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGAAIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQVAEADEAAEEEAPDSPGVEKQDKEKDQKELKKLRSMKGSSMDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSTVFGR", "length": 838 }, "evidence": [ { "id": "SGD:S000000464", "url": "https://alliancegenome.org/gene/SGD:S000000464#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P17121-1", "protein_name": "GTPase-activating protein SAC7", "gene_name": "SAC7", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPNNTLKQGSKIENVSPSKGHVPSFWKQFINNPKSMSSENITVPRSPTSLSRNAQPTTLKRPPLSSRPYSYNTPTKDRKSFSKSAKQNNNNNNANSGTSPHAEFKNYRDMFLSNRNGFTGRVFGVTLAESLSVASAEVIVQSELVSFGRIPIVVAKCGAYLKANGLETSGIFRIAGNGKRVKALQYIFSSPPDYGTKFNDWETYTVHDVASLLRRYLNNLAEPLIPLSLYEQFRNPLRSRPRILRHMLTHEVSHPNANKTNNVTVKSSRQNYNDDGANDGDIEKEDAKDDEEKRRRKIRHKRRLTRDIRAAIKEYEELFVTLSNDTKQLTIYLLDLLSLFARQSQFNLMSGRNLAAIFQPSILSHPQHDMDPKEYELSRLVVEFLIEYSYKLLPHLLKLAKREQQERLSTENKKNNGDKQKTDPIEIPKITSSDSPPIVSSNKNPPAIDNNNKLDHTTLSPISTSIPENSSDLQTSKMLKPPKQRRPHSKSFGSTPVPPDVIASNKRRTSLFPWLHKPGILSDTGDNGDLTATEAEGDDYEEENVDPYGQSPSSVHSGSLPKQHYLPIPRMNRSLSGNSTNSSFNTRPISMILTSGNDNSADQLELLSNTHSNNERSNALPLTEDDGDERNSRSRKRESWFQRLTSRSGSANRA", "length": 654 }, "evidence": [ { "id": "HGNC:24852", "url": "https://alliancegenome.org/gene/HGNC:24852#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P38339-1", "protein_name": "RHO GTPase-activating protein RGD1", "gene_name": "RGD1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEETAKKPASATVSAKSSHDGGTDDLAHLFSTPEIKKVLNSDVAINALLSRLKQSLLTCEEFMKFIRKKYAFEEEHVQELSKQYKHFFNIQGSTNSSLKKMIHEVLGFDGKMAQVKQSYITALQKMYSEISSLLLTMTKLRKSVKENSKRLEKDVSDAIHSAEKAQSRYNSLCQDWDKLRMTDPTKTKLTLRGSKTTKEQEEELLRKIDNADLEYKQKVDHSNSLRNTFITKERPRIVQELKDLILEIDTAMTIQLQKYTIWTENLVLNTGVTISPLDSTKSMKSFAGSVSNERDLYSFLNKYNQTGKHSLLINKNLIPVSYKKHPSMNHGQKNKSPPKFAVDPSRNSIPKRMISTHNESPFLSSSSNTAAVPNANLNSATPSLNTNKQLPPTMASSISSTSNAAGAMSPSSSIVTSDTTSSITKTLDPGNNSPQIPEELINSLDSDRPISHIQTNNNMPPGVQKNFKTFGVPLESLIEFEQDMVPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDKDPANISMILPSKPHSDSDIYLVGSLLKTFFASLPDSVLPKALSSEIKVCLQIEDPTTRKNFMHGLIYNLPDAQYWTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTIAPANPDDANDVNFQIMAMEVLLEVSDQAFEPE", "length": 666 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-130530-823", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-823#orthology", "database": "AGR" }, { "id": "SGD:S000000464", "url": "https://alliancegenome.org/gene/SGD:S000000464#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q12128-1", "protein_name": "Rho-GTPase-activating protein BAG7", "gene_name": "BAG7", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFNMNLLSTPSSEEGSPQNRSSSMSSVEGKKDRDTFTNLQNEFDGKVFGVSLEESLKVAQEEVIIQKSTNEIGSIPVVIAKSGKYLKENALDTTGIFRIAGSNKRVRELQAVFSKPPDYGRKFEGWCDFNVHDIATLLKRYLNSLSEPLVPLALYDIFRNPILENPKINEHKEQIIKDYEDIYMLLPQQNRHLILYLAALLNLFARNEKKNLMSASNLAAIVQPSLLSHPKDEMCPKEYEASRTVIEFLILHASDIIPNTEKANKDTMPHAGTVAKFNNITVPEMAIDSDEEDFVHPSIDDHMLPRSRALSDSNNFTIHHHHHHHHALFPSPIDFDNNGLSVPRSFKGRTLSAESLSPRLSKLLGNVGNSSNTGIKDPTERVPRGEHKTKHKQRQSWLRRLTSPSRTQP", "length": 409 }, "evidence": [ { "id": "HGNC:24852", "url": "https://alliancegenome.org/gene/HGNC:24852#orthology", "database": "AGR" }, { "id": "MGI:1926066", "url": "https://alliancegenome.org/gene/MGI:1926066#orthology", "database": "AGR" }, { "id": "RGD:1565577", "url": "https://alliancegenome.org/gene/RGD:1565577#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q53QZ3-1", "protein_name": "Rho GTPase-activating protein 15", "gene_name": "ARHGAP15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQKSTNSDTSVETLNSTRQGTGAVQMRIKNANSHHDRLSQSKSMILTDVGKVTEPISRHRRNHSQHILKDVIPPLEQLMVEKEGYLQKAKIADGGKKLRKNWSTSWIVLSSRRIEFYKESKQQALSNMKTGHKPESVDLCGAHIEWAKEKSSRKNVFQITTVSGNEFLLQSDIDFIILDWFHAIKNAIDRLPKDSSCPSRNLELFKIQRSSSTELLSHYDSDIKEQKPEHRKSLMFRLHHSASDTSDKNRVKSRLKKFITRRPSLKTLQEKGLIKDQIFGSHLHKVCERENSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELPEPLFPYSFFEQFVEAIKKQDNNTRIEAVKSLVQKLPPPNRDTMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQIAELMLSEYSKIFGSEED", "length": 475 }, "evidence": [ { "id": "SGD:S000000464", "url": "https://alliancegenome.org/gene/SGD:S000000464#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AYC5-1", "protein_name": "Rho GTPase-activating protein 15", "gene_name": "Arhgap15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKRTSCSVQTSTNCDNSLETLNSAHQATGAVQMRIKNANSHPDRQSQTKSMILTDAGKVTEPISRHRRNHSQHVLKDVIPPLEHPMVEKEGYLQKAKIADGGKKLRKNWSTSWIVLSGRKLEFYKDPKQQALPNVKPRPNAESVDLCGAHIEWAAKDKSSKKSVFQITTASGNEFLLQSDIDFLILDWFHAIKNAIDRLPKNPSFGSLELFSFQRSSSSEQPSHCHIDRKEQKPENRKSFMFRLHHSVSDTSDKNRVKSRLKKFISRRPSLKTLQEKGIIKDQIFGSHLHTVCEREHSTVPWFVKQCIEAVEKRGLEVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFVEAIKKQDSDAKIETMKSLVKSLPPPNHDTMKILFGHLTKIVAKAAQNLMSTQSLGIVFGPTLLRAENESGNVAVHMVYQNQVAEFMLTEYDKIFSSEED", "length": 482 }, "evidence": [ { "id": "SGD:S000000464", "url": "https://alliancegenome.org/gene/SGD:S000000464#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PGG2-1", "protein_name": "GEM-interacting protein", "gene_name": "Gmip", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSAETELTPAPEGRKRYSDIFQSLDNLEISLGNVTFDPLAGDPVRREDLEPDKADTATVVTEENSEASSWRDLSPEGPAPLTEEELDLRLIRTKGGVDAALEYAKAWSRYAKELLAWTDKRANYELEFAKSIMKLAEAGKVSILQQSQMPLQYIYTLFLEHDLSLGALALETVAQQKRDYYQPLAAKRMEIEKWRKEFKEQWLKEQKRMNEAVQALRRSELQYIQRREDLRARSQGSPEDPPSQASPGSNKQQERRRRSREEAQAKAHEAEALYQACVREANSRQQDLETTKRRIVSHVRKLVLQGDEVLRRVTLGLFELRGAQAERGPRSFSALAECCVPFEPGQRYQEFVRTLQPGAPPPPSPAFCFQEFTAVVHSFPQDTKKKFSGPLPPRLEEEGSPEPGPWEVASLGSQGIPGSDVDSVGGGSESRSLDSPTSSPGAGARRLVKASSTGTESSDDFEERDPDLGDGIENGVGSPFRKWTLSTAAQTHRLRRLRGPAKCRECEAFMVSGTECEECFLTCHKRCLETLLILCGHRRLPARMSLFGVDFLQLPRDFPEEVPFVITRCTAEIEHRALGLQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDITSVLKRFLQELTDPVVPFHLYDAFISLAKTLHADPGDDPGTPNPSPEIIRSLKTLLVQLPDSNYSTLRHLVAHLFRVAARFEENKMSANNLGIVFGPTLLRPPDGPRATGASPVACLLDSGHQAQLVEFLIVHYEQIFGMDELPLASEPLTQDPGLAPACLESSPQHPASLLAQDTQPLTIALDSSPDPKHHSALEKCPEVTPPELATLQRDQREEEVEDTRDGAGDGSSHCPEDLALGAQSRGHFSRQPVKYSRGGVRPVTHQLSSLALVASKLCEETPVTVSAVHRGSLRVRGLGPAAACPEGSPLRRNPLPKHFEITQETARLLSKLNSDAVSRTTCCADPEPEESEEHL", "length": 971 }, "evidence": [ { "id": "HGNC:24852", "url": "https://alliancegenome.org/gene/HGNC:24852#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-823", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-823#orthology", "database": "AGR" }, { "id": "MGI:1926066", "url": "https://alliancegenome.org/gene/MGI:1926066#orthology", "database": "AGR" }, { "id": "RGD:1565577", "url": "https://alliancegenome.org/gene/RGD:1565577#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6TLK4-1", "protein_name": "Rho GTPase-activating protein 27", "gene_name": "Arhgap27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAADVEGDVYVLVEHPFEYTGKDGRLIAIQPNERCRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGDPVPAPQPSVLQQRPTVPEPLAYDYRFVSTPVGADGSSAEPRGRASSLCGPARQRTSGQRNSLAPGGPACLYLRPAAPVRPAQSLDDLARGGTAPPAGLLGSAGHFKASSVAGSWVCPRPLARSDSENVYEAIPDLRCPPRAKSPKQVDEPPEPVYANVERQPQVTSPRSAAAPPRLSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEAPEGATSPTTSRASVGSGESLETEWGQYWDEESGRVFFYNPLTGETVWEDETEELEDDPEEQLEMQPSLSPRSPGQQRPPTPETDYPELLTSYPEEDYSPVGSFSDLGPTSPLVAPPGWSCQITPEKQMLYTNQFTQEQWVRLEDQEGKPYFYNPEDSSVQWELPQVPVPAPRSGRKSSQDSDTPAQASPPEEKIKTLDKAGVLHRTKTVDKGKRLRKKHWNASWTVLEGGVLTFFKDSKTSAASGLRQPSKLSTPEYTVELRGASLSWAPKDKSSKKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAEGIEELSADLPQREEGEPSSADFGSSERLGSWKEEDVRPNAASPSLNPGSQESDLSRVRHKLRKFLQRRPTLQSLREKGYIKDQVFGCALAQLCERERSPVPRFVQQCIRTVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFHQFIAAIKLQDPAQRSRCVRDLVRTLPAPNHDTLRLLIQHLCRVIEHGEQNRMSVQNVAIVFGPTLLRPEMEEASMPMTMVFQNQVVELILHQCADIFPPH", "length": 869 }, "evidence": [ { "id": "SGD:S000000464", "url": "https://alliancegenome.org/gene/SGD:S000000464#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZUM4-1", "protein_name": "Rho GTPase-activating protein 27", "gene_name": "ARHGAP27", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAADVVGDVYVLVEHPFEYTGKDGRRVAIRPNERYRLLRRSTEHWWHVRREPGGRPFYLPAQYVRELPALGNPAAAAPPGPHPSPAAPEPLAYDYRFVSAAATAGPDGAPEESGGRASSLCGPAQRGAATQRSSLAPGLPACLYLRPAAPVRPAQSLNDLACAAVSPPAGLLGSSGSFKACSVAGSWVCPRPLARSDSENVYEVIQDLHVPPPEESAEQVDDPPEPVYANIERQPRATSPGAAAAPLPSPVWETHTDAGTGRPYYYNPDTGVTTWESPFEAAEGAASPATSPASVDSHVSLETEWGQYWDEESRRVFFYNPLTGETAWEDEAENEPEEELEMQPGLSPGSPGDPRPPTPETDYPESLTSYPEEDYSPVGSFGEPGPTSPLTTPPGWSCHVSQDKQMLYTNHFTQEQWVRLEDPHGKPYFYNPEDSSVRWELPQVPVPAPRSIHKSSQDGDTPAQASPPEEKVPAELDEVGSWEEVSPATAAVRTKTLDKAGVLHRTKTADKGKRLRKKHWSASWTVLEGGVLTFFKDSKTSAAGGLRQPSKFSTPEYTVELRGATLSWAPKDKSSRKNVLELRSRDGSEYLIQHDSEAIISTWHKAIAQGIQELSAELPPEESESSRVDFGSSERLGSWQEKEEDARPNAAAPALGPVGLESDLSKVRHKLRKFLQRRPTLQSLREKGYIKDQVFGCALAALCERERSRVPRFVQQCIRAVEARGLDIDGLYRISGNLATIQKLRYKVDHDERLDLDDGRWEDVHVITGALKLFFRELPEPLFPFSHFRQFIAAIKLQDQARRSRCVRDLVRSLPAPNHDTLRMLFQHLCRVIEHGEQNRMSVQSVAIVFGPTLLRPEVEETSMPMTMVFQNQVVELILQQCADIFPPH", "length": 889 }, "evidence": [ { "id": "SGD:S000000464", "url": "https://alliancegenome.org/gene/SGD:S000000464#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q811M1-1", "protein_name": "Rho GTPase-activating protein 15", "gene_name": "Arhgap15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKRTSCSVQTSTNCDNSLEILNSAHQATGAVQMRIKNANSHQDRQSQTKSMILTDAGKVTEPISRHRRNHSQHVLKDVIPPLEHPMVEKEGYLQKAKIADGGKKLRKNWSTSWIVLSGRKIEFYKDSKQQALPNMKTRHNVESVDLCGAHIEWAKEKSSRKSVFQITTVSGNEFLLQSDIDFLILDWFQAIKNAIDRLPKNPSCGSLELFNLQRSSSSELPSHCHIDRKEQKPEHRKSFMFRLHHSASDTSDKNRVKSRLKKFISRRPSLKTLQEKGLIKDQIFGSHLHTVCEREHSTVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVVTGALKMFFRELSEPLFPYSFFERFVEAIKKQDSNEKIETMRSLVKRLPPPNHDTMKILFRHLTKIVAKASQNLMSTQSLGIVFGPTLLRAENESGNVAVHMVYQNQIAEFMLTEYDKIFSSEED", "length": 481 }, "evidence": [ { "id": "SGD:S000000464", "url": "https://alliancegenome.org/gene/SGD:S000000464#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8C0D4-1", "protein_name": "Rho GTPase-activating protein 12", "gene_name": "Arhgap12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAERSGKITAGQAYIEVEYDYEYDAKDRKIVIRQGERYLLVKKTNDDWWQVRPDENSKAFYVPAQYVKEVTRKALMPPVKQATGLPNNSMKTIQSMHLQRSTENVNKMPELSSFGKPSSSVQGTGLIRDANQNFGSNYNSGQTLNLSLDLTHNNGKFNSDSHSPKVSSQNRTRLFGHFPGPEFLDIEKTSFSQEQSCDSAGEGSERIQQDSESGDELSSSSTEQMRATTPPNQGRPDSPVYANLQELKISQSALPPLPGSPAIQVNGEWETHKDSSGRCYYYNRTTQERTWKPPRWARDVSTSRDFQSPGEQEPLSSEENYHSSCFSQSDSQCGSPPRGWSEELDERGHTLYTSDYTKEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDSNDKDSPTTTKLCLPENESPPTSSKHQDPGQEKYGLLNVTKITENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGAVIEMASKDKSSKKNVFELKTRQGTELLIQSDNDAVINDWFKVLSSTINNQVAEADEAAEEETPDSPGVEKHDKEKDQKELKKLRSMKGSSMDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVTAVKDLIRQLPKPNQDTMQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELILLELSTVFGR", "length": 838 }, "evidence": [ { "id": "SGD:S000000464", "url": "https://alliancegenome.org/gene/SGD:S000000464#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IWW6-1", "protein_name": "Rho GTPase-activating protein 12", "gene_name": "ARHGAP12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMADRSGKIIPGQVYIEVEYDYEYEAKDRKIVIKQGERYILVKKTNDDWWQVKPDENSKAFYVPAQYVKEVTRKALMPPVKQVAGLPNNSTKIMQSLHLQRSTENVNKLPELSSFGKPSSSVQGTGLIRDANQNFGPSYNQGQTVNLSLDLTHNNGKFNNDSHSPKVSSQNRTRSFGHFPGPEFLDVEKTSFSQEQSCDSAGEGSERIHQDSESGDELSSSSTEQIRATTPPNQGRPDSPVYANLQELKISQSALPPLPGSPAIQINGEWETHKDSSGRCYYYNRGTQERTWKPPRWTRDASISKGDFQNPGDQELLSSEENYYSTSYSQSDSQCGSPPRGWSEELDERGHTLYTSDYTNEKWLKHVDDQGRQYYYSADGSRSEWELPKYNASSQQQREIIKSRSLDRRLQEPIVLTKWRHSTIVLDTNDKESPTASKPCFPENESSPSSPKHQDTASSPKDQEKYGLLNVTKIAENGKKVRKNWLSSWAVLQGSSLLFTKTQGSSTSWFGSNQSKPEFTVDLKGATIEMASKDKSSKKNVFELKTRQGTELLIQSDNDTVINDWFKVLSSTINNQAVETDEGIEEEIPDSPGIEKHDKEKEQKDPKKLRSFKVSSIDSSEQKKTKKNLKKFLTRRPTLQAVREKGYIKDQVFGSNLANLCQRENGTVPKFVKLCIEHVEEHGLDIDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVITGALKMFFRELPEPLFTFNHFNDFVNAIKQEPRQRVAAVKDLIRQLPKPNQDTMQILFRHLRRVIENGEKNRMTYQSIAIVFGPTLLKPEKETGNIAVHTVYQNQIVELILLELSSIFGR", "length": 846 }, "evidence": [ { "id": "SGD:S000000464", "url": "https://alliancegenome.org/gene/SGD:S000000464#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q92619-1", "protein_name": "Rho GTPase-activating protein 45", "gene_name": "ARHGAP45", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSRKKRELMKTPSISKKNRAGSPSPQPSGELPRKDGADAVFPGPSLEPPAGSSGVKATGTLKRPTSLSRHASAAGFPLSGAASWTLGRSHRSPLTAASPGELPTEGAGPDVVEDISHLLADVARFAEGLEKLKECVLRDDLLEARRPRAHECLGEALRVMHQIISKYPLLNTVETLTAAGTLIAKVKAFHYESNNDLEKQEFEKALETIAVAFSSTVSEFLMGEVDSSTLLAVPPGDSSQSMESLYGPGSEGTPPSLEDCDAGCLPAEEVDVLLQRCEGGVDAALLYAKNMAKYMKDLISYLEKRTTLEMEFAKGLQKIAHNCRQSVMQEPHMPLLSIYSLALEQDLEFGHSMVQAVGTLQTQTFMQPLTLRRLEHEKRRKEIKEAWHRAQRKLQEAESNLRKAKQGYVQRCEDHDKARFLVAKAEEEQAGSAPGAGSTATKTLDKRRRLEEEAKNKAEEAMATYRTCVADAKTQKQELEDTKVTALRQIQEVIRQSDQTIKSATISYYQMMHMQTAPLPVHFQMLCESSKLYDPGQQYASHVRQLQRDQEPDVHYDFEPHVSANAWSPVMRARKSSFNVSDVARPEAAGSPPEEGGCTEGTPAKDHRAGRGHQVHKSWPLSISDSDSGLDPGPGAGDFKKFERTSSSGTMSSTEELVDPDGGAGASAFEQADLNGMTPELPVAVPSGPFRHEGLSKAARTHRLRKLRTPAKCRECNSYVYFQGAECEECCLACHKKCLETLAIQCGHKKLQGRLQLFGQDFSHAARSAPDGVPFIVKKCVCEIERRALRTKGIYRVNGVKTRVEKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRLYHELVGLAKDSLKAEAEAKAASRGRQDGSESEAVAVALAGRLRELLRDLPPENRASLQYLLRHLRRIVEVEQDNKMTPGNLGIVFGPTLLRPRPTEATVSLSSLVDYPHQARVIETLIVHYGLVFEEEPEETPGGQDESSNQRAEVVVQVPYLEAGEAVVYPLQEAAADGCRESRVVSNDSDSDLEEASELLSSSEASALGHLSFLEQQQSEASLEVASGSHSGSEEQLEATAREDGDGDEDGPAQQLSGFNTNQSNNVLQAPLPPMRLRGGRMTLGSCRERQPEFV", "length": 1136 }, "evidence": [ { "id": "SGD:S000000464", "url": "https://alliancegenome.org/gene/SGD:S000000464#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9BRR9-1", "protein_name": "Rho GTPase-activating protein 9", "gene_name": "ARHGAP9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSDWWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQALPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAGPQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCKSWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTSQLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFYREPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHETELRAWHRALRTVIERLVRWVEARREAPTGRDQGSGDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRSSIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFLRLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDLDSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALALSESEQCLSQIQELIGSMPKPNHDTLRYLLEHLCRVIAHSDKNRMTPHNLGIVFGPTLFRPEQETSDPAAHALYPGQLVQLMLTNFTSLFP", "length": 750 }, "evidence": [ { "id": "SGD:S000000464", "url": "https://alliancegenome.org/gene/SGD:S000000464#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9P107-1", "protein_name": "GEM-interacting protein", "gene_name": "GMIP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDAAEPGLPPGPEGRKRYSDIFRSLDNLEISLGNVTLEMLAGDPLLSEDPEPDKTPTATVTNEASCWSGPSPEGPVPLTGEELDLRLIRTKGGVDAALEYAKTWSRYAKELLAWTEKRASYELEFAKSTMKIAEAGKVSIQQQSHMPLQYIYTLFLEHDLSLGTLAMETVAQQKRDYYQPLAAKRTEIEKWRKEFKEQWMKEQKRMNEAVQALRRAQLQYVQRSEDLRARSQGSPEDSAPQASPGPSKQQERRRRSREEAQAKAQEAEALYQACVREANARQQDLEIAKQRIVSHVRKLVFQGDEVLRRVTLSLFGLRGAQAERGPRAFAALAECCAPFEPGQRYQEFVRALRPEAPPPPPPAFSFQEFLPSLNSSPLDIRKKLSGPLPPRLDENSAEPGPWEDPGTGWRWQGTPGPTPGSDVDSVGGGSESRSLDSPTSSPGAGTRQLVKASSTGTESSDDFEERDPDLGDGLENGLGSPFGKWTLSSAAQTHQLRRLRGPAKCRECEAFMVSGTECEECFLTCHKRCLETLLILCGHRRLPARTPLFGVDFLQLPRDFPEEVPFVVTKCTAEIEHRALDVQGIYRVSGSRVRVERLCQAFENGRALVELSGNSPHDVSSVLKRFLQELTEPVIPFHLYDAFISLAKTLHADPGDDPGTPSPSPEVIRSLKTLLVQLPDSNYNTLRHLVAHLFRVAARFMENKMSANNLGIVFGPTLLRPPDGPRAASAIPVTCLLDSGHQAQLVEFLIVHYEQIFGMDELPQATEPPPQDSSPAPGPLTTSSQPPPPHLDPDSQPPVLASDPGPDPQHHSTLEQHPTATPTEIPTPQSDQREDVAEDTKDGGGEVSSQGPEDSLLGTQSRGHFSRQPVKYPRGGVRPVTHQLSSLALVASKLCEETPITSVPRGSLRGRGPSPAAASPEGSPLRRTPLPKHFEITQETARLLSKLDSEAVPRATCCPDVQPEEAEDHL", "length": 970 }, "evidence": [ { "id": "HGNC:24852", "url": "https://alliancegenome.org/gene/HGNC:24852#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-823", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-823#orthology", "database": "AGR" }, { "id": "MGI:1926066", "url": "https://alliancegenome.org/gene/MGI:1926066#orthology", "database": "AGR" }, { "id": "RGD:1565577", "url": "https://alliancegenome.org/gene/RGD:1565577#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVF1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVF1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVF1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVF1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1" } ], "pmid": "" }, { "name": "negative regulation of small GTPase mediated signal transduction", "id": "GO:0051058", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051058", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVF1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 685, "end_pos": 687, "annotation": "n_glycosylation_sequon" }, { "start_pos": 807, "end_pos": 809, "annotation": "n_glycosylation_sequon" }, { "start_pos": 898, "end_pos": 900, "annotation": "n_glycosylation_sequon" }, { "start_pos": 971, "end_pos": 973, "annotation": "n_glycosylation_sequon" }, { "start_pos": 974, "end_pos": 976, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UVF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1" }, { "id": "PS51741", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51741" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-BAR", "eco_id": "ECO_0000259", "start_pos": 102, "end_pos": 362, "start_aa": "Gln", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UVF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1" }, { "id": "PS50081", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50081" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Phorbol-ester/DAG-type", "eco_id": "ECO_0000259", "start_pos": 495, "end_pos": 541, "start_aa": "Thr", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "A0A8N7UVF1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVF1" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 551, "end_pos": 755, "start_aa": "Thr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 770 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 685, "end_pos": 687 }, { "start_pos": 807, "end_pos": 809 }, { "start_pos": 898, "end_pos": 900 }, { "start_pos": 971, "end_pos": 973 }, { "start_pos": 974, "end_pos": 976 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVK1-1", "uniprot_ac": "A0A8N7UVK1", "uniprot_id": "A0A8N7UVK1_DANRE", "mass": { "chemical_mass": 57412.0, "monoisotopic_mass": 57412.0 }, "refseq": { "ac": "XP_696682", "name": "ankyrin repeat domain-containing protein 33B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696682" }, "gene_names": [ { "name": "ankrd33ba", "type": "recommended", "evidence": [ { "id": "A0A8N7UVK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK1" } ] }, { "name": "ankrd33ba", "type": "synonym", "evidence": [ { "id": "XP_696682", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696682" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 33B isoform X1", "type": "synonym", "evidence": [ { "id": "A0A8N7UVK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK1/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 33B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_696682", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696682" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_696682", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696682" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVK1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ankrd33ba", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040724-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-39", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "568270", "url": "https://www.ncbi.nlm.nih.gov/gene/568270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ERPCPYQ", "url": "https://omabrowser.org/oma/group/ERPCPYQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVK1", "url": "https://www.orthodb.org/?gene=A0A8N7UVK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_696682", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696682", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVK1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRA7", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRA7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRA7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRA7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040724-39", "url": "https://zfin.org/ZDB-GENE-040724-39", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVLITDSRDGGGSSPGKVKPLKHAKGAQICPTIVEESPDHTGNDDYDEFLGTCEFDGNNEDFEELDDFSELPDTRSIASDDSFYPPDDDFADSERTPSPESPAPLSFFQACCGNNALIVKLMIRQGVTEEDVRETDKNKRTGLIVACYQGYVDVVMALSQCPHLDVNWSDNEGNTALITASQAGHITICNYLLNYFPGLDIEKRNCHGFSALMKAAMQGRVECVKALMMAGADLEARDNGRKFTAREWAIFTSRHETVLTIMRLMHQPCADQFCDSYRPEWPLLPALVAKAQAPKGCIQKISETLRDFFDISNVTEASEDGVLDHMVRMTTALGSPFIATSCRTVCPGSPPCVGKRRYAVQEILKKRRIEQLKILGPERIENYKRLFQNSRVLLVPKPKDRRASLQPNAQAEDSSTLTIRRTSLLPLHLLRRSSVRPGLVVPKVRITKAPTPTYVPERVRRKSSCVEEQFLQIPKWRYKELKEERKKAEEAERKRLEAITKRQLTTGKRK", "length": 510, "header": "tr|A0A8N7UVK1-1|A0A8N7UVK1_DANRE Isoform 1 of Ankyrin repeat domain-containing protein 33B isoform X1 OS=Danio rerio OX=7955 GN=ankrd33ba PE=4 SV=1 CANONICAL=A0A8N7UVK1-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVK1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK1/entry#A0A8N7UVK1-1", "sequence": { "sequence": "MVLITDSRDGGGSSPGKVKPLKHAKGAQICPTIVEESPDHTGNDDYDEFLGTCEFDGNNEDFEELDDFSELPDTRSIASDDSFYPPDDDFADSERTPSPESPAPLSFFQACCGNNALIVKLMIRQGVTEEDVRETDKNKRTGLIVACYQGYVDVVMALSQCPHLDVNWSDNEGNTALITASQAGHITICNYLLNYFPGLDIEKRNCHGFSALMKAAMQGRVECVKALMMAGADLEARDNGRKFTAREWAIFTSRHETVLTIMRLMHQPCADQFCDSYRPEWPLLPALVAKAQAPKGCIQKISETLRDFFDISNVTEASEDGVLDHMVRMTTALGSPFIATSCRTVCPGSPPCVGKRRYAVQEILKKRRIEQLKILGPERIENYKRLFQNSRVLLVPKPKDRRASLQPNAQAEDSSTLTIRRTSLLPLHLLRRSSVRPGLVVPKVRITKAPTPTYVPERVRRKSSCVEEQFLQIPKWRYKELKEERKKAEEAERKRLEAITKRQLTTGKRK", "length": 510, "header": "tr|A0A8N7UVK1-1|A0A8N7UVK1_DANRE Isoform 1 of Ankyrin repeat domain-containing protein 33B isoform X1 OS=Danio rerio OX=7955 GN=ankrd33ba PE=4 SV=1 CANONICAL=A0A8N7UVK1-1" }, "locus": {} }, { "isoform_ac": "A0AC58IRA7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK1/entry#A0AC58IRA7-1", "sequence": { "sequence": "MKAAMQGRVECVKALMMAGADLEARDNGRKFTAREWAIFTSRHETVLTIMRLMHQPCADQFCDSYRPEWPLLPALVAKAQAPKGCIQKISETLRDFFDISNVTEASEDGVLDHMVRMTTALGSPFIATSCRTVCPGSPPCVGKRRYAVQEILKKRRIEQLKILGPERIENYKRLFQNSRVLLVPKPKDRRASLQPNAQAEDSSTLTIRRTSLLPLHLLRRSSVRPGLVVPKVRITKAPTPTYVPERVRRKSSCVEEQFLQIPKWRYKELKEERKKAEEAERKRLEAITKRQLTTGKRK", "length": 298, "header": "tr|A0AC58IRA7-1|A0AC58IRA7_DANRE Computationally mapped isoform of Ankyrin repeat domain-containing protein 33B isoform X2 OS=Danio rerio OX=7955 GN=ankrd33ba PE=4 SV=1 CANONICAL=A0A8N7UVK1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZZJ5-1", "protein_name": "Ankyrin repeat domain 33B", "gene_name": "ANKRD33B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLLAGPGPEGGGARRVSPQPPSPPRGAQAEEDPADYEDYEDFSSLPDTRSIASDDSFYPSGGEEEYSSVSSESVPEGFPEGVPEAATLLRAASANDVGLLRALVRRGPSAEEVQETDRNGRTGLIIACYHGFVDTVVVLAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPSLDLERRNLFGFTALMKAAMQGRTECIRALMLAGADVHARDPHRGMSPQEWATYTGRFEAVRVIQRLLERPCPEQFGEKYKPELPPPNEAGLKPAGSKNCLQRLTEFVRSKLMSRSHQGLEDGGVLDHMVRMTTSLYSPPVAIVCQTVCPENPPCVGKRRLAVQEILAARGDLHTQAQEKDKAEGTVQQFRTSQTAGVSREGSPRASPSPTSSQLPAAPRRTSLLPLQLLRRSSVRPGVVIPKVRISKAPAPTFQPERAARGSTKDSTHLQLPKWRYKEAKEEKRKAEEAEKQRLAATQKEKRAPSWRKRT", "length": 490 }, "evidence": [ { "id": "A0A8N7UVK1", "url": "https://omabrowser.org/oma/group/A0A8N7UVK1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M9PLN2-1", "protein_name": "Ankyrin repeat domain-containing protein 33B", "gene_name": "ankrd33bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVLITENGVAGGVVLVKVHKHDTEDNRARGWTNEESSIQSSTVVEPNEDSYYADDDEDHHFYDDDDDDDDVYQEFEELDFSKLPDSRSMASDDSFYPPDDSLSFEKCPSPESPEPVSFFKACCSNNVIIVKIMIRQGVTEAEVREVDKNNRTGLIVACYQGYVDVVIALSQCPHVDVNWQDNEGNTALINAAQAGHSMITHYLLNYFPGIDTERRNCHGFTALMKAAMQGRAECVRSLMMTGGDIEARDFGRKLTPQEWALFTGRYETAKLISRLMDKPCAEQFCDSYHMGWPMLSEMVARSKEPKSCWRKFSECICNMFNISMKTNPVDEGVMDYTVRMTTALASPLIATACHTVCPGSPPCVGKRRPAVQDILRRQRLAELKNLGPDRLNNYKRLFQNSRVLLVPKKQERRASLQPQLLHSVAMASTVALRRNSLLPLHMMRRSSVRPGMVVPKVMLCKAPPPIHMPERPPRRSSNDSAQLQIPKWKYKALKEEKKKAEQMERLRLPIGRKK", "length": 514 }, "evidence": [ { "id": "RGD:1564227", "url": "https://alliancegenome.org/gene/RGD:1564227#orthology", "database": "AGR" }, { "id": "MGI:1917904", "url": "https://alliancegenome.org/gene/MGI:1917904#orthology", "database": "AGR" }, { "id": "HGNC:35240", "url": "https://alliancegenome.org/gene/HGNC:35240#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NCL7-1", "protein_name": "Ankyrin repeat domain-containing protein 33B", "gene_name": "ANKRD33B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLLAGTGPEGGGARCMTPPPPSPPRGAQVEEDPADYEEFEDFSSLPDTRSIASDDSFYPFEDEEEHGVESAESVPEGVPESVPETATLLRAACANNVGLLRTLVRRGVSVEEAQETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHAIITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTDCIRALMLAGADVHARDPRRGMSPQEWATYTGRVDAVRLMQRLLERPCPEQFWEKYRPELPPPPEAARKPAGSKNCLQRLTDCVLSVLTPRSVRGPEDGGVLDHMVRMTTSLYSPAVAIVCQTVCPESPPSVGKRRLAVQEILAARAARGPQAQEEDEVGGAGQRGRTGQEDADSREGSPRAGLPPALGSRGPAAPAPRKASLLPLQRLRRRSVRPGVVVPRVRVSKAPAPTFQPERPARKGSTKDSGHLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRTAPWKKRT", "length": 494 }, "evidence": [ { "id": "RGD:1564227", "url": "https://alliancegenome.org/gene/RGD:1564227#orthology", "database": "AGR" }, { "id": "MGI:1917904", "url": "https://alliancegenome.org/gene/MGI:1917904#orthology", "database": "AGR" }, { "id": "HGNC:35240", "url": "https://alliancegenome.org/gene/HGNC:35240#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-39#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D3ZTU7-1", "protein_name": "Ankyrin repeat domain 33B", "gene_name": "Ankrd33b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLLAGPGPEGGGTRCLSPQSPTPPRSVQTGDDPADYEEYEDFSSLPDTRSIASDDSFYPPGGEEECGSVCAESVPEGVPESATLLRAACANDVGLLRALVRRGPSSEEARETDRNGRTGLIIACYHGFVDTVVALAECPHIDVNWQDSEGNTALITAAQAGHATITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMLAGADVQARDPRRGLSPQEWAAYTGRAEAVRVMQRLMERPCPEQFGDKYKLELPLPAETILKKAGSKNCLQRFTAFLRSTLTSRSGQSLEDGGVLDHMVRMTTSLYSPAVAVVCQTVCPENPPCVGKRRLAVQEILAARGNLDAQAQDSNNVELQSQILETPRASSRSPQSLGSGSTPAPVTRKASLLPLQLLRRSSVRPGVVVPRVRISKAPAPTFQPERAASKGNTKDSIYLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKERRAPRWRKRT", "length": 481 }, "evidence": [ { "id": "RGD:1564227", "url": "https://alliancegenome.org/gene/RGD:1564227#orthology", "database": "AGR" }, { "id": "MGI:1917904", "url": "https://alliancegenome.org/gene/MGI:1917904#orthology", "database": "AGR" }, { "id": "HGNC:35240", "url": "https://alliancegenome.org/gene/HGNC:35240#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-39#orthology", "database": "AGR" }, { "id": "A0A8N7UVK1", "url": "https://omabrowser.org/oma/group/A0A8N7UVK1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BQ20-1", "protein_name": "Ankyrin repeat domain 33B", "gene_name": "ANKRD33B", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLLAGPGPEGGGARRVSPEPPSPPRDAQAGEDPADYEEYEDFSSLPDTRSIASDDSFYPYGDEEEYSSVSAESAPEPVPEGVPEAATLLRAACANDVGLLRALVRRGPSAEEVQETDRNGRTGLIVACYHGFVDTVVILAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPGLDLERRNAFGFTALMKAAMQGRTECIRALMLAGADVHARDSRRGMSSQEWATYTGRFEAVRVIQRLLERPCPEQFGVKYKPELPLALEAGQKPTGSKSCLQKLTDFVRSTLTSRSRQGMEDGGALDHMVKMTTSLYSPAVAIVCQTVCPESPPCVGKRRLAVQEILASRGDQDTQAQERDKGEGPEPQSQTSQAAGVSKEEAPRAGLASSQPPVAPRRASLLPLQLLRRSSVRPGVTIPKVRVSKAPAPTFQPERAARGSTKDSSHLQLPKWRYKEAKEEKRKAEEAEKQRLAAAQKEKRTSSWRKRT", "length": 488 }, "evidence": [ { "id": "A0A8N7UVK1", "url": "https://omabrowser.org/oma/group/A0A8N7UVK1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3U0L2-1", "protein_name": "Ankyrin repeat domain-containing protein 33B", "gene_name": "Ankrd33b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLLAGPGPEGGGTRCLSPQSPTPPRSEQTGEDPADYEEYEDFSSLPDTRSIASDDSFYPPGGEEEYGSVSAESVPEGVPEAATLLRAACANDVGLLRALVRRGPSSEEVRETDRNGRTGLIVACYHGFVDTVVALAECPHVDVNWQDSEGNTALITAAQAGHVTITNYLLNYFPGLDLERRNIFGFTALMKAAMQGRTECVRALMMAGADVQARDPRRGLSPQEWAAYTGRAEAVRVIQRLMERPCPEQFGDKYKLELPLPAEAVLKKSGSKNCLQRFTAFLRSTLTSRSSGQSLEDGGVLDHMVRMTTSLYSPAVAVVCQTVCPENPPCVGKRRLAVQEILAARGNLNAQAQDSNKVECSEPQSQILETPRASSRSPKSPAASRSTPAPVTRKASLLPLQLLRRSSVRPGVVVPRVRISKAPAPTFQPERAASKGNTKDSIYLQIPKWRYKEAKEEKRKAEEAEKKRQAEAQKEKRAPRWRKRT", "length": 486 }, "evidence": [ { "id": "RGD:1564227", "url": "https://alliancegenome.org/gene/RGD:1564227#orthology", "database": "AGR" }, { "id": "MGI:1917904", "url": "https://alliancegenome.org/gene/MGI:1917904#orthology", "database": "AGR" }, { "id": "HGNC:35240", "url": "https://alliancegenome.org/gene/HGNC:35240#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040724-39", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-39#orthology", "database": "AGR" }, { "id": "A0A8N7UVK1", "url": "https://omabrowser.org/oma/group/A0A8N7UVK1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 313, "end_pos": 315 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVK4-1", "uniprot_ac": "A0A8N7UVK4", "uniprot_id": "A0A8N7UVK4_DANRE", "mass": { "chemical_mass": 35366.0, "monoisotopic_mass": 35366.0 }, "refseq": { "ac": "XP_683600", "name": "retinol dehydrogenase 10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683600" }, "gene_names": [ { "name": "rdh20", "type": "recommended", "evidence": [ { "id": "A0A8N7UVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4" } ] }, { "name": "rdh20", "type": "synonym", "evidence": [ { "id": "XP_683600", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683600" } ] } ], "protein_names": [ { "name": "Short-chain dehydrogenase/reductase 3", "type": "recommended", "evidence": [ { "id": "A0A8N7UVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.300", "type": "synonym", "evidence": [ { "id": "A0A8N7UVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4/entry#names_and_taxonomy" } ] }, { "name": "Retinal short-chain dehydrogenase/reductase 1", "type": "synonym", "evidence": [ { "id": "A0A8N7UVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4/entry#names_and_taxonomy" } ] }, { "name": "retinol dehydrogenase 10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_683600", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683600" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_683600.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_683600", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683600" } ] }, { "annotation": "Catalyzes the reduction of all-trans-retinal to all-trans-retinol in the presence of NADPH.", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVK4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4#function" }, { "database": "UniProtKB", "id": "ARBA00059620", "url": "https://www.uniprot.org/uniprotkb/ARBA00059620#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVK4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rdh20", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131127-122", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-122", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd05339", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05339", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "555864", "url": "https://www.ncbi.nlm.nih.gov/gene/555864", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IFWAKFR", "url": "https://omabrowser.org/oma/group/IFWAKFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVK4", "url": "https://www.orthodb.org/?gene=A0A8N7UVK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24322:SF691", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24322:SF691", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_683600", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683600", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "25033", "url": "https://www.rhea-db.org/rhea/25033", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UVK4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVU1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVU1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVV5", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JVV5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JVV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131127-122", "url": "https://zfin.org/ZDB-GENE-131127-122", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MIFLMDLQVMLLDVLYFILRSCLRLVFRPRTKPIDGELVLITGSGGALGRLFALEFTKHGAEVVLWDVNGEANEDTAKLVRARGGQAHAYTVDVTKREEVYRTADLVREEVGRDVTYLVNNAGVVAGERLLDCPDYLLERTLKVNCHALFWTVKAFLPQMKDKNHGHIITIASVLGLFSTACVEDYCASKFAAVGFHESLAHELLTEDLDGVKTTLVCPYIVDTGMFEGCRIREEVALILPPLEPLYCVQQAMNAILIDQPLVCIPRLTYLPFLARALLPWESNAVTYRFMGSDNCMYPFIETMKKRGGNSPLKAD", "length": 316, "header": "tr|A0A8N7UVK4-1|A0A8N7UVK4_DANRE Isoform 1 of Short-chain dehydrogenase/reductase 3 OS=Danio rerio OX=7955 GN=rdh20 PE=3 SV=1 CANONICAL=A0A8N7UVK4-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVK4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4/entry#A0A8N7UVK4-1", "sequence": { "sequence": "MIFLMDLQVMLLDVLYFILRSCLRLVFRPRTKPIDGELVLITGSGGALGRLFALEFTKHGAEVVLWDVNGEANEDTAKLVRARGGQAHAYTVDVTKREEVYRTADLVREEVGRDVTYLVNNAGVVAGERLLDCPDYLLERTLKVNCHALFWTVKAFLPQMKDKNHGHIITIASVLGLFSTACVEDYCASKFAAVGFHESLAHELLTEDLDGVKTTLVCPYIVDTGMFEGCRIREEVALILPPLEPLYCVQQAMNAILIDQPLVCIPRLTYLPFLARALLPWESNAVTYRFMGSDNCMYPFIETMKKRGGNSPLKAD", "length": 316, "header": "tr|A0A8N7UVK4-1|A0A8N7UVK4_DANRE Isoform 1 of Short-chain dehydrogenase/reductase 3 OS=Danio rerio OX=7955 GN=rdh20 PE=3 SV=1 CANONICAL=A0A8N7UVK4-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVU1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4/entry#A0AC58JVU1-1", "sequence": { "sequence": "MAFKTVKAFLPQMKDKNHGHIITIASVLGLFSTACVEDYCASKFAAVGFHESLAHELLTEDLDGVKTTLVCPYIVDTGMFEGCRIREEVALILPPLEPLYCVQQAMNAILIDQPLVCIPRLTYLPFLARALLPWESNAVTYRFMGSDNCMYPFIETMKKRGGNSPLKAD", "length": 169, "header": "tr|A0AC58JVU1-1|A0AC58JVU1_DANRE Computationally mapped isoform of Retinol dehydrogenase 10-B isoform X2 OS=Danio rerio OX=7955 GN=rdh20 PE=4 SV=1 CANONICAL=A0A8N7UVK4-1" }, "locus": {} }, { "isoform_ac": "A0AC58JVV5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4/entry#A0AC58JVV5-1", "sequence": { "sequence": "MFFTLLSPIGRNASVKSPMQMTVKAFLPQMKDKNHGHIITIASVLGLFSTACVEDYCASKFAAVGFHESLAHELLTEDLDGVKTTLVCPYIVDTGMFEGCRIREEVALILPPLEPLYCVQQAMNAILIDQPLVCIPRLTYLPFLARALLPWESNAVTYRFMGSDNCMYPFIETMKKRGGNSPLKAD", "length": 186, "header": "tr|A0AC58JVV5-1|A0AC58JVV5_DANRE Computationally mapped isoform of Retinol dehydrogenase 10-B isoform X3 OS=Danio rerio OX=7955 GN=rdh20 PE=4 SV=1 CANONICAL=A0A8N7UVK4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABZ3NNF2-1", "protein_name": "Short-chain dehydrogenase/reductase 3", "gene_name": "Dhrs3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVWKWLGALVVLPLQMIYLVTKAAVGLVLPPKLRDLSRESVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQMAKAVREKVQPTGTGCPHGSTAPSCPQVGDITILVNNAAVVHGKSLMDSDDDALLKSQHVNTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQQNQALLLLPWTMNILIILKSILPQAALEEIHRFSGTYTCMNTFKGRT", "length": 321 }, "evidence": [ { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A1L1W4-1", "protein_name": "Retinol dehydrogenase 10-A", "gene_name": "rdh10a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNIFVEFFLVMLKVCWAIVMAGFKWLIRPKEKSVAGQVCVITGAGGGLGRLFAKEFARRRATLVLWDINSHSNEETAEMVRQIYREQDNPMSKEGAVGGVEEVPPFQPQVYTYVLDVGKRESVYSTAEKVRREVGEVDLLINNAGVVSGHHLLECPDELIERTMVVNCHAHFWTTKAFLPKMLEMNHGHIVTVASSLGLFSTAGVEDYCASKFGAIGFHESLSHEIQASEKDGIKMTLVCPYLVDTGMFRGCRIRKEIEPFLPPLRPEFCVKQAMRAILTDQPMICTPRIVYMVNFMKSILPFEAIVCMYRFLGADKCMYPFLAQRKEAMNNNEAKNGI", "length": 339 }, "evidence": [ { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZN35-1", "protein_name": "Short chain dehydrogenase/reductase family 16C, member 6", "gene_name": "Sdr16c6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHAVADTVIFFGKFLYYFLESLVFKVIPKRRKDVSGEIVLITGAGSGLGRLLAMHFANHGATLVLWDINQEGNMETYKLVKQKGDVKVFAYKCDCSNRTEVYRVADQVREEVGDVTILINNAGIVTGKSFLDTPDHLVEKSFLVNAISHFWICKTFLPAMINANHGHLVCISSIAGVVGINGLSDYSSSKFAAFGLAESLFLELTMVRKTNIKSTIVCPYFIKTGMFEGCKTKYPLLLPLLEQEFVAQKIFHAILEDQVYLLIPKFAYFTLFLKQLISPKMMIALGEYLGVDTCMTSFTGRAEAELLQTETERKEQ", "length": 316 }, "evidence": [ { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZS85-1", "protein_name": "Short chain dehydrogenase/reductase family 16C, member 5", "gene_name": "Sdr16c5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPCNLESAKDLLVFLGKSLLSILEALLSHVISKPRKNVAGEVVLITGAGSGLGRLLALQFARLGSVLVLWDVNKETNEETRQIAQEAGAIRVHAYTCDCSQREEVYRVADQVKKEVGDVSILINNAGIVTGRKFLDCPDDLMEKSLDVNFKAHLWMYKAFLPAMIANNHGHLVCISSSAGLIGVNGLSDYCASKFAALGFAESMFVETLAQKQRGIKTTIVCPFFIKTGMFEGCTTKCPNLLPILDPEYAVRKIVDAILQEQLYLYMPKFLYFIMFLKSFLPIKTGILIADYLGLFHVMDGFTGQKKKS", "length": 309 }, "evidence": [ { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75911-1", "protein_name": "Short-chain dehydrogenase/reductase 3", "gene_name": "DHRS3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVWKRLGALVMFPLQMIYLVVKAAVGLVLPAKLRDLSRENVLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVEAVQLNQALLLLPWTMHALVILKSILPQAALEEIHKFSGTYTCMNTFKGRT", "length": 302 }, "evidence": [ { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88876-1", "protein_name": "Short-chain dehydrogenase/reductase 3", "gene_name": "Dhrs3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVWKWLGALVVFPLQMIYLVTKAAVGMVLPPKLRDLSRESVLITGGGRGIGRHLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNREEVYQMAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHVNTLGQFWTTKAFLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTVLPFHTSTEMFQGMRVRFPNLFPPLKPETVARRTVDAVQQNQALLLLPWTMNILIILKSILPQAALEEIHRFSGTYTCMNTFKGRT", "length": 302 }, "evidence": [ { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q05A13-1", "protein_name": "Short-chain dehydrogenase/reductase family 16C member 6", "gene_name": "Sdr16c6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSVADTAIFFGKFLYYFLESLVFKVIPKRKKDVSGEIVLITGAGSGLGRLLAIHFASHGATLVLWDINQEGNMETCRLVKQKGDVKVFAYKCDCSSRIEVYRVADQVKEEVGDVTILINNAGVVTGKSFLNTPDHLVEKSFLVNAISHFWTCKAFLPAMVKANHGHLVCISSIAGLVGINGLSDYSSSKFAAFGFAESLFLELTMIMKTKVKSTIVCPYFIKTGMFEGCTTKYPLLLPLLEQEYVAQKIFNAILEEQVYLIIPKFAYVALFLKQIISPKMMIALGEYLGVDTCMTSFTGRVKAEELQMETKRKEQ", "length": 316 }, "evidence": [ { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q06417-1", "protein_name": "Uncharacterized oxidoreductase TDA5", "gene_name": "TDA5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNIDCLCRWVVLPLLRYPLLVALVLRWSLSDSISICLTIYTLLINAFLIANSYIKRSGQVAWKSLREFKNGIVLITGGSKGLGRAIVSQLLQDYSNLTILNVDICPSSVRNTRVKDLICDLSDDEEVAALLNLLKRKYKNEIRLIVNNAGVRANFTGFNGMERDNLDKIFKINTFAPLQFIQELAPSRHSTRQCYIVNIASILGILTPAKVAAYAASKAALIAFHQSYSFELQNEGVRNIRTLLVTPGQLNTEMFAGFKPPRQFFAPVIDITTLAAKIVRYCELGQRGQLNEPFYCSFAHLLMCVPYSLQRIVRSFSRIDCCLPDE", "length": 326 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-131127-122", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-122#orthology", "database": "AGR" }, { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q07530-1", "protein_name": "Uncharacterized oxidoreductase YDL114W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVRKNKINRASGTTKHLKDFPSVILSLPSYNPSILSKNATALITGGSSGLGFELAKELSRRINKVIVADIQSFPTFAQVEYNNIFYYQCDITSLDEIKNLKKAIERDHGNINIIINNAGVAHIKKLEHMTNKEVEQLIDINLIGAYRIISTFAEDMIDNREGFIINIASVLGELTPARLTSYGASKGAMIGFHKCMSRHFRSLSTECNKTGIKTLLVCPGKIKTNMFIDVPTPSKLLAPDIIPSQLALAIISAMEHNHLQTLNAPYYVNLVPFFKTLSWPYRHLLKHFSGMDHVTSTSPRAINPKRSA", "length": 308 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-131127-122", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-122#orthology", "database": "AGR" }, { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5M875-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase 13", "gene_name": "Hsd17b13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNLILELLLLVGIIIYSYLESLVKFFIPQRRKSVAGQTVLITGAGHGIGRLTAYEFAKQKSRLVLWDISKHGVEETAAKCRKLGAVVHVFVVDCSNRAEIYKSVDQVKKEVGDIEIVVNNAGAIYPADLLSTKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHRVIPYLIPYCSSKFAAVGFHRALTAELDTLGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLEPDEVARSLIDGILTNKKMIFVPSYINISLIVEMFFPERVLKAINRIQNIQFEAIVGHRTKRK", "length": 300 }, "evidence": [ { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AYS8-1", "protein_name": "Estradiol 17-beta-dehydrogenase 11", "gene_name": "Hsd17b11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKYLLDLILLLPLLIVFCIESFIKRLIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRKLGAQVHPFVVDCSQREEIYSAVRKVKEEVGDVSILVNNAGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMMKNNHGHVVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALGCTGVRTSCLCPNFINTGFIKNPSTNLGPTLEPEEVVEHLMHGILTNQKMIFVPGSIALLTVLERVFPERFLDVLKRRINVKFDAVVGYKDK", "length": 298 }, "evidence": [ { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7T2D1-1", "protein_name": "Retinol dehydrogenase 10-B", "gene_name": "rdh10b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNIATELFVVTFKIIWSFVLAGAKWFIRPREKSVEGQVCVITGAGSGLGRLFALEFARRRATLVLWDINRQSNEETAEMAREIYRQLKPSTGSSDSVQELPLLQPKVYTYMCDVSKRESVYLTAEKVRSEVGDIDLLINNAGVVSGRHLLDCPDELIERTMMVNCHAHFWTTKAFLPKMLELNHGHIVTVASSLGLFTTAGVEDYCASKFGAIGFHESLSHELKAADKDGIKMTLVCPFLVDTGMFEGCKIRKEMAPFFPPLKPEYCVKQAMRAILTDQPMICTPRVMYMVTFMKTVLPFDAIVCMYKFIGADKCMYPFLAQRKESTNNNESKTGI", "length": 336 }, "evidence": [ { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q7TQA3-1", "protein_name": "Epidermal retinol dehydrogenase 2", "gene_name": "Sdr16c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQNLESVKNLLVFLGKSLLSVLEALLFHVISKPRKNVAGEIVLITGAGSGLGRLLALQFARLGAVLVLWDVNKEANDETHQLAREAGAARVHAYTCDCSRREEVYRVADQVKKEVGDVSILINNAGIVTGRNFLDCPDDLMEKSFDVNFKAHLWMYKAFLPAMIANNHGHLVCISSSAGLIGVNGLSDYCASKFAALGFAESMFIETLAKKQWGIKTTIVCPFFIKTGMFEGCTTKCPTLLPILDPEYAVRKIIDAILQEQLYLYMPKFLYFIVFLKSILPIKTGILIADYLGVFHMTEGFTGQKKKT", "length": 309 }, "evidence": [ { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q7Z5P4-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase 13", "gene_name": "HSD17B13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNIILEILLLLITIIYSYLESLVKFFIPQRRKSVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNPSTRLWPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASAILNRMQNIQFEAVVGHKIKMK", "length": 300 }, "evidence": [ { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80ZF7-1", "protein_name": "Retinol dehydrogenase 10", "gene_name": "Rdh10", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNIVVEFFLVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPPCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "length": 341 }, "evidence": [ { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IZV5-1", "protein_name": "Retinol dehydrogenase 10", "gene_name": "RDH10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMKAILTDQPMICTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "length": 341 }, "evidence": [ { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N3Y7-1", "protein_name": "Epidermal retinol dehydrogenase 2", "gene_name": "SDR16C5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFNLQSSKKLFIFLGKSLFSLLEAMIFALLPKPRKNVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKTGMFEGCTTGCPSLLPILEPKYAVEKIVEAILQEKMYLYMPKLLYFMMFLKSFLPLKTGLLIADYLGILHAMDGFVDQKKKL", "length": 309 }, "evidence": [ { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8NBQ5-1", "protein_name": "Estradiol 17-beta-dehydrogenase 11", "gene_name": "HSD17B11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFLLDILLLLPLLIVCSLESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSLGPTLEPEEVVNRLMHGILTEQKMIFIPSSIAFLTTLERILPERFLAVLKRKISVKFDAVIGYKMKAQ", "length": 300 }, "evidence": [ { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VCH7-1", "protein_name": "Retinol dehydrogenase 10", "gene_name": "Rdh10", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNIVVEFFVVTFKVLWAFVLAAARWLVRPKEKSVAGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAALQAGKGEEEILPPCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRIRKEIEPFLPPLKPDYCVKQAMRAILTDQPMVCTPRLMYIVTFMKSILPFEAVVCMYRFLGADKCMYPFIAQRKQATNNNEAKNGI", "length": 341 }, "evidence": [ { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8VCR2-1", "protein_name": "17-beta-hydroxysteroid dehydrogenase 13", "gene_name": "Hsd17b13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNLILEFLLLVGVIIYSYLESLVKFFIPRRRKSVTGQTVLITGAGHGIGRLTAYEFAKQKSRLVLWDINKRGVEETADKCRKLGAVVHVFVVDCSNRAEIYNSVDQVKREVGDVEIVVNNAGAIYPADLLSAKDEEITKTFEVNILGHFWIIKALLPSMLRRNSGHIVTVASVCGHGVIPYLIPYCSSKFAAVGFHRALTAELDTLGKTGIQTSCLCPVFVNTGFTKNPSTRLWPVLEPEEVARSLINGILTNKKMIFVPSYINISLILEKGPGFSSKHPHGGSQQPVTPIPGDLTPSSDFLKH", "length": 304 }, "evidence": [ { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9EQ06-1", "protein_name": "Estradiol 17-beta-dehydrogenase 11", "gene_name": "Hsd17b11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKYLLDLILLLPLLIVFSIESLVKLFIPKKKKSVAGEIVLITGAGHGIGRLTAYEFAKLNTKLVLWDINKNGIEETAAKCRKLGAQAHPFVVDCSQREEIYSAAKKVKEEVGDVSILVNNAGVVYTADLFATQDPQIEKTFEVNVLAHFWTTKAFLPVMMKNNHGHIVTVASAAGHTVVPFLLAYCSSKFAAVGFHRALTDELAALGRTGVRTSCLCPNFINTGFIKNPSTNLGPTLEPEEVVEHLMHGILTEKQMIFVPSSIALLTVLERIVPERFLQVLKHRINVKFDAVVGYKDK", "length": 298 }, "evidence": [ { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VCR9-1", "protein_name": "Short-chain dehydrogenase/reductase family 16C member 6", "gene_name": "Dmel\\CG17121", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVETATTTTITRTTTAVPAGAVTVTGPTASATPTATQAAAQAHRNDETTRAIFNLKVIVFLLLLPLVLLAVFLKHLLDYLFALGLKEKDVSGKVALVTGGGSGLGREICLELARRGCKLAVVDVNSKGCYETVELLSKIPRCVAKAYKNDVSSPRELQLMAAKVEKELGPVDILVNNASLMPMTSTPSLKSDEIDTILQLNLGSYIMTTKEFLPKMINRKSGHLVAVNALAGLVPLPGAGIYTATKYGIEGFMESLRAELRLSDCDYVRTTVANAYLMRTSGDLPLLSDAGIAKSYPGLPTPYVAEKIVKGVLLNERMVYVPKIFALSVWLLRLLPTKWQDYMLLRFYHFDVRSSHLFYWK", "length": 361 }, "evidence": [ { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VIG6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG9265", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKNNNELSAEDAQILANGHAHPNANGVVHQKTEPVAPAADGWRQVLWNTWDAFADVAWFIICCIGYILQDLYYIAFGYPEKELNTDIALITGGGNGLGRLLAERLGKMGTKVVIWDINKKGIAETVQIVEEAGGYCKGYVVDISKKEEVYKAADVIRDEVGDITLLINNAGVVSGLHLLDTPDHLIERSFNVNVMAHFWTTKAFLPKMIENDRGHIATIASLAGHVGISKLVDYCASKFAAVGFDEALRLELEVLGHTNIRTTCICPFFIQATGMFDDVNARWVPTLNPNDVADRVIAAIRKNEKLAVIPGFLKVLLSFKWTFPWGCVGGLLKRLVPDASPHGLPSSIAVPTVPLNSNSKLTAADIAALDAELSSVTLPAKPPSMLIQRTPSLGERVL", "length": 399 }, "evidence": [ { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VKB8-1", "protein_name": "Short-chain dehydrogenase/reductase 3", "gene_name": "firl", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIEREIIHTTPASKRIFDVLKDVLQFFELYVRILLELFVSLVQIVLPKKQKDVSGEIVLITGTGHGIGRELALHYASLGSTVVCVDIDGKNNLQTVEKAKRLNLGEVYSYSCDVSKRDEVTALADRIKSDVGCISVLVNNVGIMPTHPILQQSAEEIQRVFDVNVFSQFWTIQAFLPHMQEKCRGHIICMSSIAGLVGISNLVPYCATKFAVRGLMEALHAELRQGPFRDLIRTTTIFPYMTNTGLCKHPKVKFPSILGLLDPKQVAKRIVEAHRTDLMEVTIPSCLLYINNWTRLLPDHCGLMLKDFIDSGVESDLI", "length": 318 }, "evidence": [ { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VR28-1", "protein_name": "Short-chain dehydrogenase/reductase family 16C member 6", "gene_name": "Dmel\\CG15629", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTASPGLLHMDQPLRAIYQFLLDLLVFTIKSVYYVLESIYYSLLPQRFRKLKDISGQVVLITGGGGGVGRLIALNFARLQARIVIWDINQEAIKTTVDLLAKHGYDNCKGYVVDISDREQIYQRASQVTEEVGPVDILINNAGIVCCKPFWELHDRVIQNTYNINIISHYWTVKAFLPHMMRNNRGHIVTVGSVTGMLGTYGCSDYAATKYACIGFHESLLTDLKAHGYDQIQMSLICPYYINTGMFSGVRPRMMPMLEPQYVADRIENAVRCNEVWCVLPNSIRLLTPLKCLLPAKMCWELMSRVIRGPESMMMFQGRGRVAAG", "length": 325 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-131127-122", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-122#orthology", "database": "AGR" }, { "id": "FB:FBgn0031630", "url": "https://alliancegenome.org/gene/FB:FBgn0031630#orthology", "database": "AGR" }, { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" }, { "id": "SGD:S000004418", "url": "https://alliancegenome.org/gene/SGD:S000004418#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W3K9-1", "protein_name": "Short-chain dehydrogenase/reductase 3", "gene_name": "Ldsdh1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKVTQSADNGSNANSNDIYNIVLLVVDIVMLIVKFWLAIAEAIVGLFRAPPLDDVNGKVVLITGTGHGMGKEMALQYAKLGATILCWDVNEQTNNQTVKEIKNNGGKAFGYVCNVTKREELIELAQKVRKEHGFIHVVVNNAGIMPCHPLLEHTENEIRLMYEINVLSHFWIIQAFLPDMIERNEGSIVALSSCAGLFGLINLVPYCGTKFAVRGYMAALVEELRQKNPQNNVKLTTIYPYMIDTGLCKNPRYRFPNLFKLIPADVAAGSIIEAQRQGLEEAAIPRHFVAAEKIGRLIPRKAMRLVNDFFDTGVDTDKS", "length": 320 }, "evidence": [ { "id": "SGD:S000002272", "url": "https://alliancegenome.org/gene/SGD:S000002272#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVK4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVK4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVK4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4" } ], "pmid": "" }, { "name": "all-trans-retinol dehydrogenase (NADP+) activity", "id": "GO:0052650", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052650", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVK4", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "25033", "name": "", "equation": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A1L1W4-1", "Q7T2D1-1", "A0A8M1N3S3-1", "A0A8N7UVK4-1", "A0A8M6Z277-1", "A0A8M1N061-1", "F1QT23-1" ], "evidence": [ { "id": "25033", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/25033" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8M1N061", "gene_name": "rdh12", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "A0A8M1N061", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N061" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "A0A8M1N061", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N061" } ] } ] }, { "uniprot_ac": "A0A8M1N3S3", "gene_name": "rdh12l", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "A0A8M1N3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N3S3" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "A0A8M1N3S3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N3S3" } ] } ] }, { "uniprot_ac": "A0A8M6Z277", "gene_name": "si:dkey-94e7.2", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "A0A8M6Z277", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z277" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "A0A8M6Z277", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z277" } ] } ] }, { "uniprot_ac": "A0A8N7UVK4", "gene_name": "rdh20", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "A0A8N7UVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "A0A8N7UVK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVK4" } ] } ] }, { "uniprot_ac": "A1L1W4", "gene_name": "rdh10a", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "A1L1W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1L1W4" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "A1L1W4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1L1W4" } ] } ] }, { "uniprot_ac": "F1QT23", "gene_name": "rdh8b", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "F1QT23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QT23" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "F1QT23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QT23" } ] } ] }, { "uniprot_ac": "Q7T2D1", "gene_name": "rdh10b", "activity": [ { "ec_number": "1.1.1.300", "activity": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "Q7T2D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T2D1" } ] }, { "ec_number": "1.1.1.300", "activity": "", "evidence": [ { "id": "Q7T2D1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7T2D1" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.1.1.300", "ec_name": "all-trans-retinol + NADP(+) = all-trans-retinal + NADPH + H(+).", "evidence": [ { "id": "1.1.1.300", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.300" }, { "id": "1.1.1.300", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.1.300" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVL1-1", "uniprot_ac": "A0A8N7UVL1", "uniprot_id": "A0A8N7UVL1_DANRE", "mass": { "chemical_mass": 99713.0, "monoisotopic_mass": 99713.0 }, "refseq": { "ac": "XP_683954", "name": "extracellular calcium-sensing receptor-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683954" }, "gene_names": [ { "name": "olfcq12", "type": "recommended", "evidence": [ { "id": "A0A8N7UVL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVL1" } ] }, { "name": "olfcq12", "type": "synonym", "evidence": [ { "id": "XP_683954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683954" } ] } ], "protein_names": [ { "name": "Extracellular calcium-sensing receptor-like", "type": "synonym", "evidence": [ { "id": "A0A8N7UVL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVL1/entry#names_and_taxonomy" } ] }, { "name": "extracellular calcium-sensing receptor-like", "type": "synonym", "evidence": [ { "id": "XP_683954", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683954" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_683954.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_683954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683954" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVL1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVL1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "olfcq12", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVL1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVL1", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UVL1", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd06364", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06364", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "556129", "url": "https://www.ncbi.nlm.nih.gov/gene/556129", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556129", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556129", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UVL1", "url": "https://www.orthodb.org/?gene=A0A8N7UVL1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061:SF418", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061:SF418", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_683954", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_683954", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVL1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVL1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVL1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-735", "url": "https://zfin.org/ZDB-GENE-060503-735", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLTWHRLFIKATPSKVFIINNIHRGELKRNVEMWIIAKICLYLSFSCISVASIFRSGPCQLQGQFRLNGMFQEGDLILGGLFEVHFLTVFPEQSFRTEPEPPYCEQFDMASFQQAQTMVFAIDEINRNPNLLPNITLGYYLYDNCVKLSVAFRAAMALVSGTEESFSSLNCTGPPPVIAIVGDPGSTHSIAISSILGLFRVPMVSYFATCSCLSDRKTYPSFFRTIPSDAFQVRAMVQILKRFGWTWVGLLYSDDDYGIYAAQSFQKEMQLFGACVGFSEMLPRDNNHEDIQSIVEVIQTSTARVVVVFSTEAYLLPLMDEVALKNVTGRQWIASEAWATSPVFHTQHLLPFLGGTLGIAIRRGEIQGLKEFLYYLHPDSNTRNNIVRIFWENIFGCSFEIGGRERKVCTGQEDLKSTNTAYTDVSGLRASYNAYKAVYALAHALHDLMQCEDGRGPFSGNKCADQINLQPWQVVHYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWQPSSDGAISVSTVGVVNEGASMKMVLTLKENSIFWNFKNRKPPQSVCSESCPPGTRQVRRKGLPVCCFDCLPCADGEISNTTDAIECKICPDELWPNPNKDQCVPKEEDFLSFEDPLGISLTTASLLGTCFCALVMVIFSHHRNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPKLWTCQLRHAAFGISFVLCVSSILVKTMVVIAVFKSSRPESKSAMKWFGVAQQRGTVMALTTLQIVICTVWLSMASPKPYKNSLYISSKVVYECDIGSVVGFSLLLGYIGLLAAVSFLFAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYMILFHPERNTKKSIMGRATQIK", "length": 894, "header": "tr|A0A8N7UVL1-1|A0A8N7UVL1_DANRE Isoform 1 of Extracellular calcium-sensing receptor-like OS=Danio rerio OX=7955 GN=olfcq12 PE=3 SV=2 CANONICAL=A0A8N7UVL1-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVL1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVL1/entry#A0A8N7UVL1-1", "sequence": { "sequence": "MLTWHRLFIKATPSKVFIINNIHRGELKRNVEMWIIAKICLYLSFSCISVASIFRSGPCQLQGQFRLNGMFQEGDLILGGLFEVHFLTVFPEQSFRTEPEPPYCEQFDMASFQQAQTMVFAIDEINRNPNLLPNITLGYYLYDNCVKLSVAFRAAMALVSGTEESFSSLNCTGPPPVIAIVGDPGSTHSIAISSILGLFRVPMVSYFATCSCLSDRKTYPSFFRTIPSDAFQVRAMVQILKRFGWTWVGLLYSDDDYGIYAAQSFQKEMQLFGACVGFSEMLPRDNNHEDIQSIVEVIQTSTARVVVVFSTEAYLLPLMDEVALKNVTGRQWIASEAWATSPVFHTQHLLPFLGGTLGIAIRRGEIQGLKEFLYYLHPDSNTRNNIVRIFWENIFGCSFEIGGRERKVCTGQEDLKSTNTAYTDVSGLRASYNAYKAVYALAHALHDLMQCEDGRGPFSGNKCADQINLQPWQVVHYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWQPSSDGAISVSTVGVVNEGASMKMVLTLKENSIFWNFKNRKPPQSVCSESCPPGTRQVRRKGLPVCCFDCLPCADGEISNTTDAIECKICPDELWPNPNKDQCVPKEEDFLSFEDPLGISLTTASLLGTCFCALVMVIFSHHRNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPKLWTCQLRHAAFGISFVLCVSSILVKTMVVIAVFKSSRPESKSAMKWFGVAQQRGTVMALTTLQIVICTVWLSMASPKPYKNSLYISSKVVYECDIGSVVGFSLLLGYIGLLAAVSFLFAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYMILFHPERNTKKSIMGRATQIK", "length": 894, "header": "tr|A0A8N7UVL1-1|A0A8N7UVL1_DANRE Isoform 1 of Extracellular calcium-sensing receptor-like OS=Danio rerio OX=7955 GN=olfcq12 PE=3 SV=2 CANONICAL=A0A8N7UVL1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:556129", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556129", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KAL5-1", "protein_name": "Vomeronasal 2 receptor 19 like 1", "gene_name": "Vom2r19l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTMIFLFLLLNIPLLMVDFIHPRCFWRMKQNEDKDGNPGTGCTFFLQSVHWPVEKEYYSDIFNIQMHNENHKYALALAFAIYEINGNPDLLPNMSLIFEFTRDVCDWESQLNSVIQSSLKNHNILPNYICKEFTKCPMALTGLNWTTTLKLHTILNNFISQQFLQVTYGPFHPVLSDNEKFPYLYQMASDDKSLALALVSFIIHFGWNWVGLAISNNDQGIQFLSYLRREMEKGTVCFAFVNMIPVNMHLYMSRAEMYYNQIMTSSTNVVILYGDTDSTLAVSFRMWESLGIEKIWVTNSWWAATLSKKDHTFDNLYGTYAFGQHHGEISGFKNFVQTLNPAKYSDEHLVKLEWMYFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFTGGSYDIYNAVYSFAHALHEMTFQIFDNLPKDNGREHNYSCKKLCSFLRKTSFTNPVGDRVNMNQRHKQKEEYDIFYIWNFPQGLGIKVKIGMFSPYFPNGQQLHLSEDVLEWAKGSAQMPTSACSADCGPGFRKSWKDGMATCCFHCKPCPENEISNETNVDVCARCPDDQYANIEQNRCIPKAVVFLSYEEPLGMALSLISLGFSVFTIVLLGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSAICILQQITFGVVFTVSVSTVLAKTITVILAFKVTASQRMMKYFLVSRVPNYIIPTFTLFQVILCAVWLGASPPSIDIDAKSEHGHIIIACHKGSVTTFYCVLGYLGTLASGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKIMVAVEIFSTLASSAGMLGCIFVPKCYTVLFRQDQNSLVMIRMKSSSHAHIS", "length": 857 }, "evidence": [ { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0R4IS27-1", "protein_name": "Olfactory receptor CG6 precursor", "gene_name": "olfcg6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFLFYTILLFHLLHTKVENSLCRIMGDSNYPLFSKNGDVSIGGIFAIHRKETLPSFEFMQKPQPLSCSSVNLRDFRLAQTMIFAVEEINRSKSLLPNVSIGYKIYDTCGSRLSTMTAIMGLMNGQDFSTEDRCNGQSRLHAIIGESESSATIVLSRTTGPFRIPVISHSSSCECLSNKKDYPSFFRTISSDYHMSRALVYIVKHLDWSWVGAVNSDNDYGNNGMAIFLKAAHEEGICVEYSVKFYRTEPEKLKKVVDTINKGTAKVIVAFVSFVEMGLLIDQLSIQNITGIQMIGVEPWITANTYITSNSFRAMGGSLGFATKYIYIEGFAEYVMTPFWNTAFPCSESDRNHSHYELICSRYEDLLALKNDNKDVNEHRYSSNVYKAVYAVAHSLHGLLNCKEQEGCEKGLTIQPQQVVKALKNINFTIKSGDSVWFDNTGSVVALYEVVNWQKDSDGSFQFKSVGFYDAMMPPYKNLRLNTKNIVWAGGQLEKPRSVCSESCAPGTRKAAQKGRPVCCYDCIPCAEGEISNETDSINCKQCPGEYWSNTERNRCVIKAVEFLSFSEVMGIVLVIFSLFGAGLTVLVAVLFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTKWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPVQQRLSVFAFTLIQVLICVLWLTISPPFPYKNMKYYKEKIILECNLGNTIGFWAVLGYIGLLAALCFLLAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSFGLLVSIFAPKCFIILLKPEQNTKQHVMGKTTCSL", "length": 837 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A3B2W422-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r54", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSASMWGYRVTQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQKEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSYQSLGKIEETVQKMQKCTAKVVLVFLSNLNFQLILRGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVSSLNAEETVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFVLALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQICLSPGTSTFVVLIASLIQVVLCGVWLATSPPFPDKDMISEPQHIVIQCQEGSGATFFCVLGYLGFLAGGTFSVAFLARGLPDIFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLKQGYCAQQEKQGEMLQRRYKFSGESPEPNI", "length": 878 }, "evidence": [ { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W4A7-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r53", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCTLLSVLFGCLSGSALSGPRVWIIPRQSPRFDRPGDVIVGGSFSIFHFSDGTLSNFTAPPPVLKTSSASMWSYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTCSHAVTQLVIHFQWSWVIILAHDDDFGQQASSLATQMLTPAGVCIEYHLHVPSHQSFGKIEETVQKMQKCTARVVLVFLSNSNFQLILHGLLAVPVSGQVWVSMDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSRIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHNLRNVYFKTSDGNKIMFDANGDLVTQFDIFQGKKTPAGVFHLVHVGLIDPQASSGNKMMVQLKQDLQVSSLNAEITVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTIFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQVCLSSGASTSVVLIASLIQVVLCGIWLITSPPFPDRDMISEPRHTVIQCHEGSGANFFCVLGFLGFLAGGTFSVAFLARGLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHQVQHNRQCEMLQRRCVSSGESLGSSL", "length": 878 }, "evidence": [ { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W842-1", "protein_name": "Vomeronasal 2, receptor 66", "gene_name": "Vmn2r66", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLISVFWFLKISSIFCHLSDPRCFWRIKDTKNHLGDKENNCFFSIYTKRGYVKNDYFSCNLDKQVTPKTIHLIFSVYLAIEEINKDYHILPNISLLVNIECDQRIYDKKSGLGLKSKEIIPNYYCRNQRRYLIVLTIPEWTVSTSLGPFLYISRIPELYCGNFHLLLNDNEQFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGAIVTNDDHGIQFLSELRGEMQKHIVCLSVAIIIQTEKIMALKEFHTHYNQIIMSSAKVVIVYGDKDSPIHFALIVWKSKGIWRIWVSVSQFDMITIIGDFLLYSSIGTFIFSHQQPEIPGFEQFIQTVHPSNYSSEHSLAKLWWTYFRCSLPPSNCKKLKNCPTTTVFKWLFMTPLGMAMSNTCYNLYNGVYAVALSLHEMILQQVDTWSMNAGKELEFDSWKLFYFLKTLQFVNPAGELVIMNQNLKQDTEYDIFFIMDFKKYYGLKIKIGRFSGHLPSGQQLLMSTEMIKWATGIDQILPSVCSMPCRPGLRKSPQEGKDICCFVCYPCPENEISNMTSNVIIYQNMDQCVKCPEDQYANEDQTLCLQKVVAVLDYRDPLGKALAGFALCFSVLTSVVICVFLKHRETPIVKANNQTLSYVLLISLIFCFMSSLLYIGHPTMVICILQQTTFAIVFTVAASTILAKTITVVLAFKATVPGRRMRWLLVSGAPKYIILICTMVQLILCGIWLRISPPFVDADIHMLHGQIIIVCNKGSVVAFYCVLGYMGSIALASFTVAFLARNLPHTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTTVAVEVFCILASSAGLLLCIFAPKCYLILLRPQTNSFYKFRRPHAKAENIS", "length": 858 }, "evidence": [ { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2WBA1-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r56", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLSCHWLSDPLAGMWLCTLLPVLFGCPSGSALSGARAWLLPRQSPHFDRPGDVIVGGSFSIFRFSNGTLSNFTAPPAGLQTSSVSMWGYRVAQSFVFAIEEINRSTHLLPNLTLGFSIRNSGDSAHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTSSHAVTQLIIHFQWSWVIILAHDDDFGQQASSLASQVLTPAGVCIEFYLYVPSHQSLGKIEETVRKMQKCTARVVLVFLSNYNFQLILYGLLAVPVSGQVWVSKDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCMWPYQNITVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHDMISYEHQDGKGTNSQDFQPWQLLHVLRKVHFKTPDGSEIMFDANGDLVTKFDIFQGQKTPDGVFHLVCVGLIDPQASSGNKMMVQKKMLKYQMKHAQVPTSVCSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCCIILLKPEKNTSSWLRQGHHV", "length": 865 }, "evidence": [ { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I6GK53-1", "protein_name": "Vomeronasal 2 receptor, 33", "gene_name": "Vom2r33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLCTFLFVLLGCLPGSALSEPRSWILPRQSPHFDRPGDVMVGGSFSIFCFSDGTLSNFTAPPTGLQASRVSMWGYRVAQSFVFAIEEINKSTQLLPNLTLGFSIQNSGDSVHGALYETMGFLTGQEEPIPNYTCCHGSPQAALVGDTRSSLSLPMARLLGLYKFSQISYSSSLPSLSDKIQFPSFLRTLPSDLTSCHAVTQLIIRFQWSWLIILSQDDDFGEQASSLATQQLSAAGVCIEFHLDVPSQHSLGKIEETVQKMQKCTARVVLVFLSNSNFQLILSGLLAASVSGQVWVSNDTLHIAMALSIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLHPSQIPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQVCSGNESLKNKPYPFPEVSKIDAAYTAVYSIAHALHDMVACEHQDGIDTNPQDFHPWQLLHVLKKVHFRTPDGSEIMFDANGDLVTKFDILQGQKTLNGVFHLVHVGMIDPQASSGNIMMIQLKEDLQVSSMNAEITVPTSICSERCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALMAILLAGLALLVLGVFLKHRDTPVVRVNNRTLSYFLLISLSLCSLCSLLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTVTVVLAFRVTKSGSRIQVCLSPGASTSVVLIASLIQVVLCGVWLATSPPFPERDMISEPQHIVIQCQEGSGATFFCVLGFLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHCAHQDRQCSLFH", "length": 864 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N5X2-1", "protein_name": "Olfactory receptor CW1 precursor", "gene_name": "olfcw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTPVLRAIHLVFFLFYPIQSNSEANCKLWKELDLTVVHKEGDVILAGMFPIHSKGIDQELNFRNQPDQRKCWGFNMRVFRWSQAMIFFIEEINRNPTLLPNITLGYRLYDTCGLIALSLRTALSVVSQPMKRSSSEMCSSPSIPIIIGDSGSTLSMAISRLLNLFHIPLVSYFASCACLSNKHQFPYFFRTIPSDVNQANALARLVKHFGWTWVGTVGADDAYGRTGIDLFTAAVTQLGVCVSYRIIIPKLPTQQQLQDIVRTIRDSSAHVLVAFAIEEDIKPVVDEIVLQNVTGKQWVASEAWVTSTLISTKENFPSLSGTIGFAIRRAEIPGLKHFLDSIQPLADPYNVFAREFWETQFQCTLNTSLPTSSTMDPVNYSHSCTGMERMQDTQSIFNDVSQLRVTYNMYKAVYTVAHALHNLLLCQREHRSALTQQCPDIHNLQPWQVIEVLRKVNYTNMFGDLIYFDENGDPVGSYDIVNWQKGGDDVPVQYITVGRFDSSLPKGQQLVLNQNKIVWHGGTNKVPVSVCSASCPPGYRKVRLEGQPVCCYDCMLCAEGSISNTTDQAECLLCPEDFWSNKHRNYCVPKEIEFLSYLEAFGMVLAAIAILGAVAAISVGVVFFRHRDTPLVRANNSELSFLLLISLTLCFICALTFLGQPSHWACPLRRISFGLTFALCLSCLLSKTLVVLIAFKSTLPGNNTARWFRPPQQRLGVFICSLLQGGVCIAWLTTASPYPVKNTWLYRDRIILECHLGSVVYFCCVLGYIGCLAAFCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSYGVLLCIFAPKCYIIIFMPEKNSKKYLMTQK", "length": 866 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PS22-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcx1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQIYATLLTLCLLLYIRVQCQSNNKYKCIYQGDDDTYSFYQGGDLVLGGIFPLHSSTIPQFFSFTTKPKLIQYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPEKGSGQSCEDTRKQPSPVIVGEASSGVSMAVLRTLGTFQIPLVSYFASCSCLSNKREFPAFMRTMPSDLFQIKALVKLVYYFKWTWLGVIGVDTDYARFAIQLFLKESEKYNICPAYVHIYPVALTQNTVEELVKILKSSSARVILNFSVDSYLYGVLKECRRQNVTNLQWIASEAWATSKVLWDDFGDLLKGTLGFAIRRADIPHLGSYLRSVSSSVAQTSPFFTEFWEETFHCRLNGSLNTHVHEEASYNWPACNGNETLDDVYTLYSDVSQLRVSYNVYKAVYLIAHALHDMSTCDPGKGPFKNGTCGSLYQILPWQLLYYMKRTNFTTLGEEVRFDKNGDPIASYDLMNWQRESDGSLQLVRVGIYDASFKDDKDLVIDESVIMWHRGDKAPESLCSKSCLPGSRKARQKGKPVCCFDCISCAEGEISNQTDSIDCLTCSKDTWPNQSQDQCIPKTLEFLSFQEPLGIILWVFSALGACAALAVLCVFVMYRTTPVIRGNNIELSFLLLLFLCACFLIGLTFLGKPTDWLCQIRYPAFGISFTLCISCILAKTVVVLMAFRATIPGNNVMKWFGPVKQRSSVILCTCVQALICIIWLTTKPPLASYNSKFLSATIIVECSVGSEVGFWCVLGYIGFLSSLCFFLAFLARKLPDNFNEAKFITFSMLIFFAVWITFIPVYVSSSGKYMVAVHVFAILASAFGLLMCIFAPKCYVVLLKPERNDKKSMMKK", "length": 866 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PU52-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWISLNIFLYLSLNCIFAASVVNPGTCQLQGHFKLNGMYQDGDFILGGLFEVHFFTLFPKLSFKSEPEPPYCEKFDMESFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCVMLGMAFRAAISLASGTEEYFSNLNCTGPPPVIGVVGDPGSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVRILSHFGWTWVGLIYSDDDYGIYASVSFQQEMQQFGSCISFSEILPHDNNPKDIQRIMEVIKASTASVVVVFSTSSYLMPLIDEVVLQNLTGRQWIASEAWATSPVFHTPRYLPFLGGTLGIAIRRGEILGLQEFLLHIHASNNPKDNMLKIFWENMFRCSFETRSKDTIGEQEKSICTGHEDLSTTKTPYTDVSGLRASYNVYKAVYALAHALHDLMECEEGRGPFDGNSCGNITNLKPWQLVHYLQKVNFKTGFGDHVSFDENGDALAIYDVLNWHPSSDGSIRLHTVGVVNEGAGTGKVLSLDESALYWNFQTKNPPRSVCSASCPPGTRQAMRKGLPICCFDCLPCGDGEISNATDSTECVTCPDEFWSNFDKNQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHLNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGTMKWFGAAQQRCTVLVLTALQVVICAVWLSNASPTPIKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKKAIIRRETKKR", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" }, { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q146-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYQDGDFILGGLFEVHFFTVFPDLTFTTNPKSPYCEIFNMEGFQHAQTMAFAIEEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLTSGTEESFLNLNCSGPSPVIGIVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSNRKKYPSFFRTIPSDAFQVRAIVQVLKHFKWTWVGLLYSDDDYGVYAAQSFQQEMRQFGLCAAFSEFLPHDNNPRTIQHIMGVIQGSTAKAVVVFAPSSFLIPLMNEVVLQNMTGRQWIASEAWATSLESHIPSFQPFLRGTIGIAIRRGEIQRLHDFLLRIRPSNDPKNYMLRIFWENMFGCSFGKGDTEGEQVIKVCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHALHDLMECEEGKGPFSKNSCADKTNLKPWQVVHYLQNVNFTTGFGDYVSFDKNGDALAIYDVLNWQPSSDESIRIYTVGVVKEGTETGMVLTLDEDAIFWNFETRKPPRSVCSESCPPGTRRATRKGLPVCCFDCLPCGDGEISNTTNAVECFLCPDEFWSNQYNNHCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVIFVFALHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHVVFGISFVLCMSSILVKTMVVIAVFKSSRPEGKGAIKWFGAVQQRSTVVVLTVLQVLICAVWLSTASPTPYKNNQYIRSKIVYECAIGSVVGFSMLLSYIGFLAAASFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFVPAYVSSPGKYTVAVEIFAILASTFGLLIAIFAPKCYIILLHPERNTKNVIMGRETQNK", "length": 829 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q166-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWSPLIICLYLSYNFKSAASILMGSCQLQGHFGLNGMYQAGDVILGGLFEVHLLAVFPELSFRSAPEPPYCEQFDMASFQQAQTMVFAIDEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLVSGTEELFSNLNCTGSPPVIGIVGDSNSTPSIAISSVLGLFRVPIVSYFATCSCLSNRKQYPSFFRTIPSDAFQVRAMVNILKHFGWTWVGLIYSDDDYGNYAAQSFLQDIQIYGGCVAFTEILPLNNNRKYIEHVVGVIQASTARVVVVFSTSTYVLPLMDEVVLQNVTNRQWIASEAWATSPMFHTQRLLPFLGGTLGIAIRRGEIQGLHEFLLHLRPKNDQHNNMVRIFWEKMFGCRFNPGGKGDKQCSGQEDLSSIDTAYTDVKELRASYNVYKTVYALAHALHDLTECDEERGPFSENRCADITNLQPWQLVHYLQKVNFTTGFGDHVSFDKNGDVLAIYDVMNWHPSSDGSISVRTVGVVNEGAASGKVLTLDEDAIYWNFKIKKAPQSVCSESCPPGTRQATKKGLPVCCFDCLPCGDGEISNVTNAIECTVCPDEFWSNKDKDQCVPKEVEFLSYEDPLGISLTTACLLGTCFCALVMIIFCQHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGSMKWFGTTQQRCTVLILTALQVVICIVWLSNSSPAPHKNSQHISSKIVYECAIGSLAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVTSPGKYAVAVEIFAILASSFGLLGAIFAPKCYIILLHPEKNTKKAIMGRQITK", "length": 860 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q1C5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNAHLLFTVKMLCIARLCIAVCGVDLGTCILQGDAQPPALSEDGDFIVGGAFTIHYYVRTEKYTYTRRPQPLECSGSMDFRELRFARALQFAIQEINNSSDLLPGIFLGYHIYDSCGSVPMAIKVALQLANGLDPKYNDTDSCAKSAAVLALVGDSASTPAISISRIFGPFEIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEKEGICVEYSEAYYRTYPLSKLKRVADVIRRSTARVIVAFVAAGDMRFLLEELSKEPLPPMQWIGSEAWVSDPQMLRFNLSIGTMGVAVPRSLIPGFRKFLLDLSPYKVLKFPLLTEFWESSFSCSLQQQTDPSTGMPACDGTEDLGRLKNPYTDTSQLRVSNMVYKATYAIAHALHGIVCNETQCSKNIKVKPRQVFDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPEGQEFSLNKAIIWYDGSEKVPVSVCSENCPPGTRKAVKKGRPVCCYDCIPCGEGEISNKTDSPDCDKCPPDYWPSTEKDKCLPKPVEFLSWDEILGIILAVLSVSGSLLALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWVVLGYIGLLASLCFVLAFLARKLPDNFNEAKFITFSMLIFSAVWITFIPAYVSSPGKFTVAVEIFAILASSFSLILCIFAPKFFIILFRPEENTKKHLMGKVQSKSY", "length": 856 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RHU5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCCYICVTLIASTGTCQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMTSFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTSRQWIASEAWVTAAVFRTPYFQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTTNTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEGSIKLHNIGVVNEVATGMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTSRAMRKGFPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDRCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AUZ8-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcv3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHSLETMTILLLWLLVYHLSVLNPAQASKCLLQNEFEPGLMANGDFVIGGIFPLHYNQEMPDLNFTYKPGPVKCNGFDTRAFRWAITMKLAVEEINKRVDLLPNYTLGYKIFDSCAYPLTGQRSAVAVLNGPNELESPLCADAAPLLAVIGESGSAQSIVVSRILQPFGIPMISYFSSCACLSDRREFPTFFRVIPSDAYQVKAIAKLLRHFNWTWIGVIRGDHEYGRFALQGLLKELEGTGICVAYQKMIPLLYDRQKALEIIHVMSHSTARVVVVFSAEGELTPFLRDYMEQNVTGIQWIASEAWVTSSVFAGSEFDPFLGGTIGFGIRQGQIPRLKEYLTTVNPERYPTNPLVYELWGALYGCSPSWSNLSSHLPSCTGKETVRLQYSAYLNTSSPRISYNVYKAAYAIAYSLHNLIYCTPGKGPFSNSTCANAPHIYPWQLQQYLQEVSFTISGEKVNFDMKGDSIPSYDLINWQRGSAGNIEFINVGMFDGALESGQELVIKEEAIMWPGHQTEVLVSVCSNSCAPGFRKAVRRGQPLCCFDCVPCDSGKISNETDSLDCIACSEDYWSNADGTVCIPKVVEFLSHDAMGLTLTVIAVAGACLTLAVFSVFLYYKNTPVVRINNSELSFFILLSLTLCFLCALIFIGEPTSWSCMLRHTAFSITFSLCISCILGKTLVVLAAFTATRPGNNLMKWLGPTQQRIIIFCCTLIQVLICTVWLVASPPFPYRNTKYQQSKIILDCSVGSDLAFWCVLGYIGLLACVCFFLAFLARKLPGNFNEAKYITFSMIIFCAVWLAFVPAYVSSPGKFTTAVEIFAILASSFGLLLCLFTPKVYIILVKPEKNTKQHLMGKDK", "length": 859 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AV03-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYNNVLLIVTLQCIITRLYVVYGNRLGSCILQGDPQPPVLFDEGDFIIGGAFSIHYYLRTEKHTYTMRPQSLECSGSMDFRELRFARVLQFAIQEINNSSDLLPGITLGYRIYDSCGSVPMAVKLSFQLANGLDLIFNDNDSCSKSAAVAALVGESGSTPSISISRLYGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEEEGICVEYSEAYYRTQPRSKLMRVADVIRRSTARVIVAFMASGDMRLLLEELSQQPLPPMQWIGSEAWFTDPEMLRFNMCIGGVGFAIPRSVIPGFRTFLLDLSPQRAMKFPLLTEFWESSFSCSLKQQTGPSTGMPACDGTEDLGRLKNPYTDTSQLRISNMVYKATYAIAHALHGIICNEKKCNKNIKIEPREVLDKLKQVKFSKNNYSVSFDAYGDPVAVYELVNWQLQKDGSIDFVTVGKYDSSQPKGKEFSLSRAIIWYDGTEEVPVSVCSESCPPGTRKAVQKGRPVCCYDCINCADGEISNDTDCLDCHECLSDYWPNNEKNKCLRKPVEFLSWDEILGIILAAFSVAGSLVALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPSQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFGLILCIFAPKFFIIIFRPERNTKKHIMGKVPSKAL", "length": 856 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B2Z8-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcg8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLFLYSVLSLYHLNTKAENTLCQMIGNPKYPLLSKDGDITIGALFVIHSEVSLPSFAFTQKPNLLSCSSLNIKDFRLAQTMIFAIEEINKNTNLLPNISVGYQIYDTCGSRFHSMSATMALMNGPKNSEGYTCNEQSSVHAIVGETESSNTIILSRTTGPFKIPVISPTATCECLSNRKEFPSFFRTIASDYHQSRALAYIVKHFGWTWVGAVNSDNDYGNNGMATFQKTAKEVQICVEYSVKFIRTETEKIRNVVNVIKKGTAKVIVAFLTGFEMKSLLEQLSSQNITGLQMIGVEAWITSKTLITSKSFHVLGGSLGFAVRKIQIEGFADYVMKAFWDTAFQSFSNADLNYSQYQDLLLVKNYNEDVLEQRFVSYVYKAVYALAHSLHSLLRCTEQGGCGKALTIQPHQLVEALRKVNFTVKMGDQVWFDSTGGVIAQYDVVNWQQNSDGSVQFQSVGYYDASLSPDQRFMLNTEKIVWAGGQLEKPRSVCSESCPPGTRKASQKGRPVCCHDCIPCADGEISNETDSNNCKQCPGEYWSNANKNKCVTKAVEFLSFTEVMGIILVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSIPFIGRPTQWSCMLRHTAFGITFVLCISCILGKTIVVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTLIQGLICVIWLTKSPPFPYKNMKYFQEQIILECSVGSTIGFWAVLGYIGLLAVLCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKLTVAVEIFAILASSFGLLFCIFAPKCYIILLQPEQNTKQQMMAKTPSKI", "length": 832 }, "evidence": [ { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PAH3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTKKSELLLLMVLVTHGICVPNLAQVCRLLGQPALPLLSEERNINIGAIFSLHKSALLKSHNFTSKPKQTTCGGLNLREFKFVQTLIFAIEEINNSSLLPGASLGYKIYDSCGSVAQAIFSGMALMNGYEETLSDTSCSTPPAVHAIVGESNSSPTIGLASVVGPFSLPLVSHFATCSCLSNRKRFRTFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGIATFEEAAKQEGICIEYSEAVFKTDPEVQFLKTIEVIKKATTKVVVAFMAFGDFVLLLKVMAQQNITGIQWIGSESWITSRNLAETKEYHFLSGAVGFAIANSKPVGLREFLMNVHPDKELNNELLKEFWETVFLCSFRNSSSGGCTGSEKLSELQNEYTDFSELRIENKVYTAVYAVAHSLHNVLKGFKFFTNSSKKQLPTPQKVLEYLRDVNFTVNTNENIFFDASGDPVARYDLVNWQPTKDGSLQFKLVGIYDSSLPSEQRLQINQESMLWAGNSGQLPVSVCSESCPPGTRKAVQKGRPICCYDCIPCAEGEISNYTDSSDCFPCGLEYWSNESKDRCVLKVIEFLSYTEIMGVGLCIFSFIGVLLTATVSFLFYFYKETPIVRANNSELSFLLLFSLTLCFLCSLTFIGRPTDWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLIQVIICVLWLTMSPPFPFLNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFFARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSAPGKYTVAVQLFAILASSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKS", "length": 849 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PD42-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWITLCIYLYLSLNYICAHSILRTSDSCRLQRRFHLNGMYKDGDVILGGLFQVHFFTVFPEQSFRTEPEPPFCEKFDMESFQQAQTMAFAIEEINKNPNLLPNITLGFHLYDNCVRLGMAFRAAISLASGTEESFQNLNCTGPPPVIGIVGDPSSTPSIAISSLLGLFRVPIVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLIYSDDDYGVYAAQSFHLEMQMFGHCVAFSEILPHNNNQRDIQRIMGVIQASTARVVVVFSTSSFLLPLIDEVASQNMTGRQWIASEAWATSPVYHSPRLLPFLGGTLGIAVRHGEIPGLHDFLLHLGPGNESRNNMLRIFWENMFGCSFEPGVKDTNSEIKLCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHGLHDLMQCEKGRGPFRGESCADITNLKPWQLVHYLQKVNFTTGFGDHVSFDENGDALAIYDVLNWQPSSDGSIQIFTVGVVKERTETGMVLTIDEDAIYWNFETKKSPQSVCSESCSPGTRRATRKGLPVCCFDCLPCRDGEISNTTDAIECMLCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGSCFCVLVMIIFGLHRNTPIVRANNSELSFMLLLSLKMCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGAMKWFGAAQQRCTVLVLTVLQVVICSVWLSTASPTPYKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKNAIMGRETQKR", "length": 867 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PFV7-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcg9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLYLCTLLLFFKLKVSVGNASCKIMGEPKYPLLFKDGDVTIGALFPVHSIETAPSFEFTQKPQLLSCSSVNLRDFRLAQILIFAIEEINRSESLLPKLSLGYKIYDTCSSKLSSMSATMALMNSFEFAGRDKCNGQTSVHAIIGETESSATVILTRTTGPFKIPVISHAASCECLSSRKEYPSFFRTISSDYHQGRALAYIVKHLGWSWVGAVNSDNDYGNYGMAIFLNTAHKEGICVEYSEKFYRTEPEKLKKVVDTIKKSTAKVIVAFISFLEMRLLVEQLSAENITGLQIVGVEGWTTSKSLITPKTLNVLRGSLGFAMRKIYIEGFAEYVLKPFWDTAFPCIPNQRNDSWVILNCSRYQDLLVLKNYIEDVPEHRFSINVYNAVYAVAHALHSLFKCKEQEGCEKDLLTQPQQVVDALKKVNFTVKMGDRVWFDSTGATLAQYEVVNWQQNSDGSVNFKKVGYYDASLPPDQRFVLNIKEILWAGGNLKKPRSVCSESCPPGTRKAAQKGRPICCYDCIPCADGEISNDTDSNNCKQCQGEYWSNADKNKCVQKSVEFLSFTEVMGIVLVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTQWSCMLRHTAFGITFVLCISCVLGKTLLVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTFIQVLICVLWLSISPPFPHKNMKYYEEKIILECSLGSTIGFWAILGYIGLLAALCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSISLLLCIFAPKCYIILLKPEQNTKQYMLGKTTSKFY", "length": 839 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPM0-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcg12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVFFCTLLIFFQLYAKAEKPICIMMGDPKYPLLSKEGDISIGAVFPVHSIETLPLFKFTQKPQLLSCSSVSIRDFRMAQIMAFAIEEINRNESLLPNVSLGYQIYDTCGSGLSLMGANMALMNVQEFASRGSCNGQSPVHAIIGETESSNTVILSRTTGPFKIPVISPSASCECLSNRKEYPYFFRTIASDYHQSRALAYIIKYFGWSWVGAVNSDNDYGNHGMAIFLSTAEKEGVCVEYSVKFQRTEPEKLKKVVDTIKKGTSKVIVAFLTEFEMKNLLEYLIIQNVTGLQVIGVEAWITANSMIKPNSFHVLGGSLGFAVKKLNIEGFEDYVTKAFWETAFPCSQTSQKENSQYKLICNIYRDLLVLKNDNKDVPEQRYASNVYKAVYAVAHSLHNILKCRENGACETDMKIQPQQVVEALRKVNFTIKMGDCVWFDSTGAVVAQYEVVNWQPDYNGSIQFKPVGYYDASLPPNQRFVINTENIIWAGGQLKKPRSVCSENCPPGTRKAVQKGRPVCCYDCIPCAEGEISNETDSNNCKQCPGEYWSNAEKNKCVLKAVEFLSFKELMGIVLVFFSLLGAGLTTLVAILFYSKKDTPIVKANNSELSFLLLFSLMLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSDVMKWFGPIQQRLSVLVITIVQVLICVLWLAVSPPLPYKNTKYFKEKIILECSLGSTIGFSAALGYIGLLAILCFILAFLARTLPDKFNEAKFITFSMIIFCAVWITFIPSYLSSPGKLTVAVEIFAILASSFGLLFCIFLPKCYIIMCKPEQNTKLHIIGKLNK", "length": 837 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2U8-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLCEMWITLNICLYMYFNHISGVFTSESCQLQGCFKLNGMYQDGEFIIGGLFEVQNLKVFPELSFTNEPELPQCEEFYMASFQQALTMVFAINEINSNSKLLPNITLGYQIYDNCLRLGVAFRAAMSLVSGTEESSNLSCTGPPPVIGIVGDPGSTQSITISSVLGLYRVPMVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLLYSNDDYGIYAAQSFQQEMQILGGCVAFSEMLPYDNNGRDIQRIAGVIQKSTAKVVVAFSTDLASLMDELLLQNVTGKQWIASEAWTTTPVLQTPQYLPLLGGTLGIAIRRGQIQGLYEFLKNLRPDKNPKNSTIRIFWETMFGCKFEVGGKKVDEQQERGRNKCSGQEDLNNSETAYTDVSELRASYNVYKAVYALAHALHDLVKCEEGKGPFTGNSCADISNLKPWQLVHYIQNVKFTTGFGDHVSFDENGDALAIYDVMNWHPRSDGSIIVHVVGVYEEAILGKVLTLDEDALFWNFETKKPPDSVCSESCPPGTRRARKKGLPVCCFDCLPCGDGEISNTTDSPECFICPEDFWSSPENDRCVPKEMEFLSYDDPLGISLTTASLLGTCFCVLVLVIFAYHHNTPVVRANNSELSFLLLVSLKFCFLCVLLFIGRPRLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKTSRPEGKTSIKWFGSAQQRGTVIALTSAQVAICTVWLSSASPTPHKNNQYIHSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFMARKLPDNFNEAKFITFSMLIFCAVWIAFVPAYASSPGKYAVAVEIFAILASSFGLLAAIFAPKCYIIILHPERNTKKAIMGRSTQNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2V5-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcx2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALLCATLLMVWFLMYLSVQSQYNSKVRCVFQGDDDTNTFYQGGDVVLGGLFPLHFSPISSLSSYKTKPTPTTYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPDKDSGQSCEDTRKQPSPVVVGEASSGISMAVLRSLGCFKIPLVSYFASCSCLSNKKEFPAFMRTMPSDLFQIKALAKLVHYFQWTWVGVIGVDTDYARFAIQLFLKESQQLNICLAYVQLYPVALNQDSAEELVRMLKSSSATVIISFSVDSYLYGILKECRRQNVTHLQWIASEAWATSKSLWEEFGDLLKGTLGFAIHRADIPHLGSYLKEIRPQTSHFLSEFWEETFRCRLNGSLNTHAHGEQAQNWPACNGSESLDDVYTTYSDVSQLRVSYNVYKAVYLIAHALHDMSTCVPGKGPFQNGTCGSLFQIQPWQLLYYMKQTNFTTLGEEIRFDENGDPIASYDLMNWQRGSDSSLQLVRVGFYDASLEDDKDLVIDESLIMWHRAEKAPESLCSKSCLPGSRKARQKGKPVCCFDCISCAEGEISNHTDSIECLTCSEDTWPNQSQDQCIPKTLEFLSFQEPLGIILWVFSAFGACAALAVLCVFVMYRKTPVVRGNNIELSFLLLLFLCACFLIGLTFLGKPTDWLCQIRYPAFGISFTLCISCILAKTVVVLMAFRATIPGNNVMKWFGPVKQRSSVILCTCVQALICIIWLTTKPPLASYNSKFMSETIIVECSVGSEIGFWCVLGYVGLLACLCFLMAFLARKLPDNFNEAKFITFSMLIFFAVWITFIPVYLSSSGKYMVAVHVFAILASAFGLLLCIFFPKCYIVLLKPEKNDKKHIMKK", "length": 863 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T5D2-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCYYICVTLMASTGICQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMESFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLHNLTSRQWIASEAWVTAAVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTANTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEESIKLHNIGVVNEVATEMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTRRAMRKGLPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDQCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSLAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6G6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAILLFCLFLSCNFICVTLMVSSGTCQKQGHFTLNGMHQDGDFVIGGLFEIQSYVKVYPEISFRTQPKLPNCDLFYMTSFQQALTMVFAISEINNNPNLLPNITLGYQIYDNCLRLGVAFRAATALISGTEETISDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRLPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAMVQTMRHFGWTWVGLIYSNNDYGIYAAQSFHKEMQLFGHCVAFSEILPQDNNPRVIDHIIGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTGRQWIASEAWVTSTVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETEDKETFGQQIKKVCTGQEDLSITNTPYTDVSGLRAPYNVYKAVYALAHALHDLMQCKEKRGPLSEKNCADITDLKPWQLLSYLKKVNFTTGFGDPVSFDNNGDALAIYDVLNWQPSSEGSIKLHSIGVVNDEVATGMVLRLNKDEIYWNFEAQKAPRSVCSESCPPGTRKAMRKGFPVCCFDCLTCGDGEISNTTDAIKCTVCPDEFWSNFNKDQCVPKEIEFLSYEDPLGISLTTASLLGTCFCALVMIIFAFHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFNSSRPEGKGAMQWFGAAQQRCTVLVLTVLQVVICAVWLSTSSPTPHKNNQYVRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRETKKY", "length": 869 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6Z6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcq17", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLYLSLCLCFKHIYADSIHRLRSCQLQGRFKLNGMYQDGDFILGGLFHVHFFTVFPELSFRMEPQQPYCEKFNMEGLQHAQTMAFAINEINKNPTLLPNITLGYHLYDNCVMLRMAFRAAMSLASGTEDSYSNLNCTGPPPVIGIVGDASSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKHFKWTWVGLLYSGDDYGVYAAQMFHKEMQLSGHCVAFSEILPNDHNPKDIQRIIRVIQGSTARVVVVFALSSFLIPLMDEVVLQNMTGCQWIASEAWATSLEYHTPRFLPFLGGTLGIAIRRGEIEGLHEFLLRIRPSNDTSQNIVRIFWENLFGCRFETGGLKTGREQEKMECTGQEDLSTTNTPYTDVSGLRASYNVYKAVYALAHGLHDLMQCEEGRGPFIGNSCADITSLKPWQLVHYLQNVNFTTGFGDHVTFDKNGDALAIYDVLNWQPSSDGSITVHKIGVVYEGATTGMMLTLDADAIYWNFETKKPPLSVCSESCPPGTRQATRKGLPLCCFDCLPCGDGEFSNTRDAVECMMCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGAMKWFGASQQRCTVLVLTALQVVICAVWLSTASPTPHKNNHYFRSIIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFALLLAIFAPKCYIILLHPERNTKNAIMGRETQNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TDV0-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfck1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRISLGWVVCLVKEMHVNLLLILTLLCIRRLFPAVCGVHLGTCILQGDPQPPSLFSKGDFVIGGTFTIHYYLRTEKRTYTVRPQPLMCSGSMDFRELRFARVLQFAIQEINNSSNLLPGITLGYHIYDSCASVPMVIKVAVQLANGLQLAFNDTDSCAQSSEVLALVGESGSTAAITTSRLFGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEVEGICVEYSEAYYRTQTRNKLQRVADVIRRSTARVIVAFMAAGDMRFLLEELSQQPPPPMQWIGSEAWVTDPQMLRFNLSIGAVGFAIPRSVIPGFRKFLLDLSSEQALKIPVLKEFWESSFGCSLKQHTGYFSGMPACDGTEDLGTLKNPYTDTSQLRISNMVYKATYAIAHALHGIVCNGKLCDKNIKVEPRKVSDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPKGQEFSLNRAIIWYDGTEKVPVSVCSESCPPGTRKAVKKGRPVCCYDCINCADGEINNETDSLDCHKCQPDYWPNAEKIKCLPKPVEFLSWDEILGNTLAAFSIAGSLVALSMALVFYKNRVSPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFSLILLIFAPKCFVIVFRPEENTKRHLLGKVPPKAL", "length": 870 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUY1-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWVILHIYFFISCNYMSVALMASSGTCQLQGHFTLNGMYQNGDFLIGGLFEIQYLKAFPGLSFRTEPKLPHCENFYMTSFQQAITMVFAINEINNNPNLLPNITLGYQMYDNCLRLGVAFRAATALISGTEETLSDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMIQILRHFEWTWVGLLYSDDDYGINAALSFHHDVQQFGGCVAFSEILPNDNNQMAVQHIVRVIQNSTAKVVVVFSTSSYLLPVIDEMLLKNITGRQWIASEAWSTSPVLLNPRLRYVLGGTLGIAIRRGEIEGLDNFLLRLRPDNFSQNSMMRIFWENMFECNFDTIGGLRTKLCSGQEDLRSKFTPYTDVSELRASYNVYKAVYALAHALHDLMHCEEGRGPFSENRCVDISNLKPWQLVHYLQRVKFTTGFGDHVSFDKNGDALAIYDVLNWQLSSEESVTVRRIGVVDEGVTTGKVFTLDENAIYWNFETNKPPRSVCSESCPPGTRQATRKGLPVCCFDCLPCGDGEISNTTDTTECIACPNDFWSNPEKDQCIPKEVEFLSYEDPLGISLTTAAMLGTFICALVMTIFAHYRNTPVVRSNNSELSFLLLLSLKLSFLCVLLFIGQPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKNAMKWFGAAQQRGTVLILTALQVLICAVWLSTASPTPHKNSRYIRSIIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDSFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIIILHPERNTKKAIMGKGTKNK", "length": 863 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V5L1A2-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSVSMWGYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFSQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSHQSLGKIEETVQKMQKCTSKVVLVFLSNSNFQLILHGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVPSSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPSWLKQGHHI", "length": 845 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AB13A3P1-1", "protein_name": "Olfactory receptor CG7", "gene_name": "olfcg7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSANSLFMVSLTFRMILYFYTILFLRCFQAKTENAFCQIIGEAKYPLLSKDGDVTIGGIFAIHSKETLPSFEFQQKPQPLLCSSVNLRDFRLAQIMIFAIEEINKSENLLPNVSIGYRIFDTCGSRLSSMSATMGLMNELKFAAGETCNGQSPIHAIIGETESSATVILSRTTGPFKIPVISHSASCECLSNRNDYPSFFRTISSDYHQGRALAYIVKYLGWSWVGAVNSDNDYGNYGMAIFLETAQKEGICVEYSVKFYRTETEKLKRVVDTIKKSTAKVIVAFVSFIEMGLLIEQLSIQNITGFQIIGVEGWITSKNYITTNSFHSMGGSLGLALRKIHLEGFLDYVTKSFWSTAFPCSQTEGILPTVGCSKYKDLLPLKNYTEDVPEHRYSSHVYKAIYAVAHSLHSLLKCKEGEDCEKGHATQPQQVVEALKKVNFTVKFGDRVWFDRTGATVAHYEVVNWQQDTDGSFQFKQVGYYDASLPPDQRFVLNIESIIWPGGNLEKPRSVCSESCSPGTRKAAQKGRPVCCYDCVPCADGEISNETDSVNCKQCPREYWSNGEKNKCVLKAIEFLSFTEIMGIVLVCFSLFGVGLTAVVAILFWSKMDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMVFKATLPGSNVMKWFGPTQQRLSVLAFTFIQVLICVLWLTISPPFPNKNMTYYKEKIIIECSLGSTISFWAVLGYIGLLAVLCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSFGLLLCIFAPKCYIIICKPEQNTKQHVMGKTSLKVQ", "length": 851 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TCB3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNFGAGLRTGSRNGNEKWKRMTFCRSSAFCHMFSSTLYLISSMARHAVVLRAGACQLQGRFRLNGMYQDGDVILGGLFEAHFFTLFPELTFRTEPAPPYCEIFNMESFQYAQTMAFAINEINRNPSLLPNISLGYHLYDNCVMLGMALRAAMSLVSGIEESFLNLNCTGPPPIIGVVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMIQLISHFGWTWIGLLYSDDDYGTYAAQSFHQEMQLFGFCIAFSEPLRYDSNPRDIQRLMEVIQASTSTVVVVFSPSTLVIPLMNEVVLQNMTGRQWIASESWATSPVFYTPRFLPFLGGTLGIAIRRGEIEGLREFLLQLRPKNDPRNNMLKIFWENMFGCSFETGPHVKNVCTGQEDLSTTNTPYTDVSELRAANNVYKAVYALAHALHDLMKCEEGKGPFSKNSCAEISNLKPWQLVHYLQKVNFSTRFGDHVSFNKNGDALAIYDVMNWQPGSDRSIRIHTVGVVSEELEKGLMLTLDEDAIYWNFETKKPPQSVCSESCPRGSRRATRKGHPVCCFDCLPCRDGEISNTTDATKCTVCPDDFWSNLYKDQCIPKEVEFLSYNDPLGISLTTASLLGTCFCAFVMVIFVHHHNTPIVRANNSELSFLLLFSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKMAMKWFGAAQQRCTILALTAIQVVICVVWLSTASPTPHKNNLYIRSIIVYECTIGSVTGFSMLLGYIGLLAAVSFLIAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYSVAVEIFAILASSFGLLVSIFAPKCYIILLHPERNNKKAIMGRETH", "length": 888 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0T300-1", "protein_name": "Olfactory receptor CD2 precursor", "gene_name": "olfcd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANTLSLLLLLLLLHGHFLPATVQICDLVGQSALPVLSAERDINIGAIFSIHRNALLRLYPFTSKPEPTTCVRLNLREFKFAQTFIFAIEEINNNTQLLPGVTLGYKIYDACNAISPTLVSGMALINGYENTLSDTSCSQPPAVQAIVGESSSSPTTALAALVGPFNIPVISHFATCACLSNRKRYPSFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGITAFEDAAKQEGICIEYSEAILRTDPQEQFRKTVEVIKKGTSKVVVAFISFGDFAPLVKVIAENNITGLQWVGSESWITSRNLAETKEYSFLSGAVGFAIVNAKLVGLKEFLVNVHPDQEPKNKLLKEFWETAFQCSFSNSDSALCTGSEKLGELKNEYTDVSELRIEHKAYAAVYAVAHTLHNVFKDVKAPNNSKRELPTPQKVLQYMRNLSFTIKTGENIFFDASGDPVARYDLVNWQTAEDGSLQFKHVGIYDSSLPSKQRLQVNQEIMLWAGKSGLLPLSVCTESCLPGTRKAVQKGRPVCCYDCIPCAEGEISNSTDSSDCFSCDLEYWSNEKKDRCILKVVEFLSYAEIMGIILCIVSFIGLLLTVMVTCLFYLHKETPIVRANNSELSFLLLFSLSLCFLCSLTFIGRPTQWSCMLRHTAFGITFILCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLVQVIVCLLWLTLSPPYPYMNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSSPGKYTVAVEIFAILVSSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKL", "length": 848 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0T301-1", "protein_name": "Olfactory receptor CQ19 precursor", "gene_name": "olfcq19", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWVILNISIYLIFNFIMSASILGSNTCQLQGHFRLNEMYHDGDVILGGLFEVDFLTVFPDLDFKTEPEPPYCVQFDMESFQQAQTMAFAIDEINKNPNLLPNITLGYHLFDNCVMLGMAFRAAISMASGTEEFFNNINCTGPPPVIGIVGDSSSTVSIAISSILGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKYFRWTWVGLIYSDDDYGVYAAQSFQQEMQLFGGCVAFSEVLPHDNNLEDIKHITKMIQASTARVIVVFSTPSFLIPLIDELVLQNMTDRQWIASEAWATSFVHHSPRLLPFLKGTLGIAIRRGEIQGLYEFLLRLQPTNDPKNNMIRIFWEIMFGCNFETGGKKNSGDQVINICTGQEDLRTTKTPYTEVSELRASYNVYKAVYALAHALNDLMQCEDGRGPFSVNSCADITNLKPWQLVHYLQNVNFTTDFGDHVSFDKNGDALAIYDVLNWQPSSDGSIRAQTVGVVNEEVATGMVLTLDEDALYWNFESKKPPSSVCSESCAPGTRLATIKGLPVCCFDCLPCGDGEISNITGAVECTMCPDEFWSNLDKDQCIPKEVEFLSYEDPLGISLTTASLLGTCFCVLVMFVFAVHRNTPIVRANNSELSFLLLLSLKMCFLCALLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPESKGAMKWFGAVQQRCTVLVLTAIQVVICAVWLSTASPAPHKNNQYIRSKIVYECAIGSVAGFSMLLAYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIILLHPERNTKKAIMGKEAQNT", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" }, { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z4N8-1", "protein_name": "Vomeronasal 2, receptor 72", "gene_name": "Vmn2r72", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKISFIFCHLSDPKCFWRIKDTENKIGDIETYCSFSISTKPGYVKNDYFILEIIFSTSVFRVTPKTNHLIFSVYLALEEINMNFHILPNISLVVNVECLRQKYDEKTGLALQSKEFIPNYSCTNERRYLIIFTAPIWAVTTRLGPLMFMYSIPELYCGHFHLSLSDNEQFPHLYQISPKDTSLPLAMVSLMVHFKWNWIGAMITNDDHGIQFLSKLRGEMQKHMVCLSFVFAILTEHSMVRKEFHKNFNLIVRSSAKVVIVYGDYASPIDLVLHWFKSKGLFRIWVSVSQFDIITNLGDFMLYSSSGTFIFSHQKPEISGFQKFIKTVYPSNYSSEFSFAKLWWTYFRCSLPPSNCKTLKNCPTKTVFKWLFRTPLGMAMSDTCYNSYNAIHAVAHSLHEMLLQQVDTWSNNDGKDLEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTEYDIFYIMDFQKHYGFKMKIGRFSGHLPSRQQLYMSKEMMEWATDVDQILPSACNIPCKPGFRKSPEEEMDICCFVCNPCPENEISNMTNMDQCVKCREDQYANEDHTLFLQKVVSILDYREPLGKALAGFALCFSVLTSGIFCVFLKHRETPIVKANNQTLSYVLLISLIFCFICSLLYIGHPTTVICILQQTTFAIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLVSGAPKYIILICTMIQLILCGIWLGTSPPYVDADVHMVHGHIIIVCNKGSVIAFYCVLGYMGSFALTSFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYQSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYIILLRPHINSFRNFRKPHAKTENIS", "length": 856 }, "evidence": [ { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z6L3-1", "protein_name": "Vomeronasal 2, receptor 49", "gene_name": "Vmn2r49", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFIFMGVFFLLNITLLMANFIDSRCFWRINLDEITDEYLELSCAFILAAVQTPIEKDYFNKTLNFLKTTKNHKYALALVFAMDEINRYPDLLPNMSLIIRYSLGHCDGKTVTPTPYLFHRKKQSPIPNYFCNEESMCSFLLSGPNWDESLSFWKYLDSFLSPRILQLSYGSFSSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYLKWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDEVSFPQKTEIYYKQIVKSLTNVIIIYGETYNFIDLIFRMWEPPILQRIWITTKQLNFPTSKTDISHDTFYGSLTFLPHHGEISGFKNFVQTWFHLRNTDLYLVMPEWKYINSEDSASNCKILKNSSSDASFDWLMEEKLDMAFSDNSHNIYNAVHAIAHALHEMNLQQADNQAIDNGKGASSHCLKVNSFLRRTYFTNPLGDKVFMKQRVIMQDEYDIVHFANLSEHLGIKMKLGKFSPYLPHGRHSHLYVDMIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNETNMDQCVNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMFCFLCSFFFIGLPNKVICVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRYFLVSGTLNYIIPICSLLQCELCAIWLAVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTLAFLAKNLPDAFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGMLGCIFVPKIYIILMRPERNSTQKIREKSYF", "length": 852 }, "evidence": [ { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z7M3-1", "protein_name": "Vomeronasal 2, receptor 73", "gene_name": "Vmn2r73", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLIFIFWFLKISYIFCHLSNPRCFWRIKDTKDKLGDKETYCFFSISAKHGYIRNDYFSWNLDKHVTPKTNHLIFSVYLALEEINKNSHILPNISLVVNIECVLLKYGEKTGLGLKHEEFIPNYYCANERRYLIVLTAPIWAVSTKLGPFLFMSRIPELYCGHFHLPLSDNEQFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGVIITNDNHGIQFLSELRGETQKQIVCLSVVIIIQTDDITAYKEYHMNYNKIVMSSAKVVIVYGDHNSPIKFVLFLWKSQGIFRIWVSVSQFDMITPLGDFMLYSASGTLIFSHQQSELSGFEKFIKTVKPSNYSSEFSFAKLWWTYFRCSSLPPSNCKKLKNCPTKTVFRWLFMTPLGMAMSDTCYNLYNAIYAVAHSLHEMLLQQVDTWSENAGKELEFDSWKMFSILKTMQFVNPAGDLVNMNQNLKQEREYDIFYIMDFQKDYGLKMKIGKFSGHLPSHQQLYMSKEMIEWATDMDQILPSICSMPCRPGLRKSPQEGKDICCFVCNPCPENEISNMTNMDQCVKCPEDQYANEDHTLCLQKIVAILDYRDPLGKALAGFALCFCVITSGVLCIFLKHRETPIVKANNQTLSYVLLISLIFCFICSLLYIGHPTIVICVLQQSTFAISFTVAASTILAKTITVVLAFKVTVPGRMRWLLVAGAPKYIILICTMIQLILCGVWLGTSPPFVDADLHMVHGHIIIVCNKGSVIAFYFVLGYMGSIALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWVTFIPVYYSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYNILLRPGKNSSHMFKKLHAKTENII", "length": 851 }, "evidence": [ { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZB66-1", "protein_name": "Vomeronasal 2 receptor, 26", "gene_name": "Vom2r26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFIFMVVFFLINIPLLMANVIDPRCFLRINLDEVKDGDLQSTCSFILEAVQIPMEKDYFNQTLNVLKTAKNHKYALTLAFSIDEINRNPDLLPNMSLIIKYSFGYCDGKTVTPTPYLFHEEFEKPIPNYFCKEETKCTFLLTGPHWGTSLLFLTKLDIFSSPRFLQLTYGPFHSTLNDNEQFPYLYQMAPKDTSLALAIVSFILYFNWNWVGLFISDEDQGNRFLSELKKVSESKKICFAFVSMISFSELLFHHKVEMYYDQIVMSSTSVIIIYGEGNSITELNFRIWESPVKHRIWVTTKQWNFPTSNRDLTHDTFYGTFTFQHHHGEISGFNNLVQTWYQLRSTDLCQVMPDWKYLNYEGSASNCEILENYTSGASLEWLLEQKFDMAFSDDSYNIYNAVYAMAHAFHELNLQQVDNQAIDNEKGASSHCLKLNSFLRKTHFTNPLGDKVIMKQREILQEDYDIFHTQYFSEHLGIKVKIGKVSQYFKRDQHFHLYVDMIELATGSKKMPSSVCTEDCGPGFRRIWKEGMAACCFVCKPCPENEISNDTNMDQCMNCPEYQFANTKHNKCIQKGVLFLSYEDPLGMALALIAFCFSAFTAVVLWVFVKHHDTPIVKANNRNLSYLLIISLMFCFLCTFFFIGHPNRATCILQQITFGIVFTVAVSTVLAKTATVVLAFKVTDPGRRLRNVLVSGTPNYIIPICSLFQCILCAIWLAVSPPFVDIDDYSEHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTVAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPDRNILKFREKSYF", "length": 851 }, "evidence": [ { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZE87-1", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "Vom2r78", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFILMVVFFLLNLPLLMANFIDSWCFWRINLNESKKKDLEISCAFILGAVQLPMEKDYYNETLNVLKTTKTNKYALALAFTMEEINRNPDILPNMSLIIKHTLSYCDGKTALHIAKEKFFRPLPNYVCSEESMCSFLLIGLNWMSSIILFRDLDTFFFPRFLQISYGPFHSIFSDNEQFPYLYQMTPKDTSLALAMVSFILYFNWNWIGLIISDNDEGNQFLSELKKEAQNKEICFAFVNMMAIDDISFYDKTEMYYNQIVMSSTNVIIIYGETDSIIELSFRMWESPVIQRIWVTKSELDFPTSKRDLNHGTFYGTLTFLHHHGEISEFKNFVEMWDHLRSRNLNLLISEWKYFSYETSGSNCKILRNFTSNSSLEWLTEQKFQMAFNDESNSVYNAVYAMAHALHENNLQEIDKQEIRNGKGAGTHCLKLNSFLRKTHFTNPLGDRVIMKHRERVQEDYDIVHIHNFSQHLWIKVKIGKFSPYFPNGRLFHLYGDMIELATGSKKMPSSVCSADCSPGFRKTWKEGMAACCFVCSLCPENEISNETNMDQCVNCPEYQYANKEKSKCIQKGVIFLSYDDHLGMLLAIIAFCLSAFTAAILWVFVMHHNTPIVKANNRILSYILIMSLMFCFLCSFFFIGHPNRATCILQQITFGIVFTVSVSTVLAKTITVVLAFKITDPGRRLRNFLVLGLPNYIIPICSLLQCILCTIWLAVSPPFVDIDQHSEHGNIIIVCNKGSVMAFYCVLGYLACLAFGSFTMAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGRVMVAVEVFSILASSAGMLGCIFAPKLYIILMRPDRNYIQKIREKSF", "length": 848 }, "evidence": [ { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZEQ5-1", "protein_name": "Vomeronasal 2 receptor, pseudogene 67", "gene_name": "Vom2r-ps67", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKIFFLIVVFLLLKLSFLFCHLSDPRCFWRIKDKENYQGDKDIDCFFSIYTEHGYVKNDYFSGNLDKQVTRKTIHLISSVYFAIEEINRNIHILPNISLLVKTECNLFADNVDTVRSLKKKEIIPNYYCKHQRRYLIVLTGPPWLTSYKLGPFLFFSRTPELYCGYFHFRADQEQFPHLYQMSPKDTSLPLAMVSLAVHFRWNWVGVIITDDDQGIQFLSELRTGVEKSTVCVAFVTITTDDRMLYFKMIHKYYHQIITSSAKVVIVYGDKESLIQYNFMLWKSKNVQRLWVSVSQFDMITMIGEFMLHSLHGSIIFSHQHSEMSGFKKFIQTVNPSNYSNDISFAKLWWTFFKCSLPPPNCTTLKNCPSKILSKWFFVSPLGMSMSDICYNLYNAVYAVAHSLHEMLLQHVEIYSDNDGKVVEFNSWKIFSLLKTIQFVNPAGDLVNMNQNIKLGTEYDIFYVMDFRKQEGLKMKIGRFSGHFPNDQQLFMSDEMIEWATDIKQTLVSICSVPCRPGLRKYFQEGKAVCCFDCYPCPENEISNMTDMDDCVKCPEDKYANTDKTNCLKKVVTFLDYEDPLGMTLAGLALWFSALTAIVLCVFLKHRDNPIVKANNETLSYVLLISLIFCFICSLLYIGHPSMARCILQQTTFAIVFSVAASTVLAKTITVVLAFKITLPGRRLRWLLLSGAPNYIIPICTMIQMILCGIWLGISPPFVDADLHMVHGHIIIVCNKGSVIAFYSVLGYMGSLALSSFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFLPVYHSTKGKAMVVVEVFCILTSSAGLLLCIFVPKCYIILLRPQINSFHNFSKMRAKATSIN", "length": 853 }, "evidence": [ { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZVB5-1", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "Vom2r28", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFILMEVFFFFLNIPLLMANFIDPKCFWRVNLNEVKDKDLSITCSFILEAVQMPTENDYFNQTLNILKTTKNHKYALALAFSIDEINRNPDLLPNMSLIIKYPLGLCDGQTTLPTPYLFNEIYFRPIPNYFCNEETMCTFLLTGPHWITSYSFWIHLNIFLSPSFLQLTYGPFHSTFSDNEQFPYLYQMNPKDTSLALAMVSFLLYFKWNWVGLVISDDDQGNQFLSELKKESKIKEICFAFVSMLAIDEISFYHKTEMYYNQIVMSSTNVIIIYGKTESIIELSFRMWESPVIQRIWVTTKEMNFPTSKRDLTHDTFYGTLTFLHSHGEISGFKNFVQTWYHLRITDLHLVMPEWKYFNYEASASNCKILKNYSSSASLEWLMEQTFDMVFSDGSRDIYNAVNAMAHALHEMNLHLVDNQAIDNGKGASSHCFKINSFLRKTHFTNPLGDRVIMKEREILQEDYNIFHTWNFSQHIGFKVKIGKFSPYFPHGRHFHLYVDMIELATGSRKMPSSVCTEDCSPGYRRFWKEGMAACCFVCSPCPENAISNETNMDQCVNCPEYQYANTKRDKCIQKNVMFLSYKDPLGMTLAFIAFFFSALTAVVLRVFVKHHDTPIVKANNRILSYLLITSLLFCFLCSFFFIGHPNRATCILQQITFGIVFTVAISTILAKTITVVLAFKVTNPGRRLRNFLVLGTLNYIIPICSLFQCILCAIWLAVSPPFVDTDEHTEYGHIIIVCNKGSVTAFYCVLGYLACLALASFTVAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKIMVAVEIFSILASSAGMLGCIFAPKIYIILMRPERNAIQKIREKSYF", "length": 853 }, "evidence": [ { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AB78-1", "protein_name": "Vomeronasal 2 receptor, 43", "gene_name": "Vom2r43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSLILVLLFLKASLLFCTLNDPKCFLRIKDKKNVDGDKEVDCFFSIYAKHGHVKNDFFSGNLDKQLTTKNIHLILSLYFSIEEINSTPQVLPNISLLVKIECNLLADRSKISLSSRKGDYFPNFDCRNQRRYLIVFTGPMWFPTAMLGPLLYISRTPELYYGPFHPLLNTYEQFPYLYQMAIKDTSIAIGMVTLVIYFSWNWVGLMISDDDLGLQFASELREEMQRYDICLAFVTVITYNSKLFLTMAGMYYNQIIMSLAKVVIIYGDIDSFLQVIFRLWQFVDIRRIWIATSQWDIITSNGEFLFNSFHGTLSFSHHYSEISGFKEFIQTVYPLNYSNTISPAKLWWVNFNCFWPSSNCKKLKKCSRKMLLKWLSNNQFEMAMSETNYNLYNAVYAVAHSLHELILQQANTLSNNVEKELEFDSLQVLSSLKKIQFVNPAGDLVNLNQKENLNVDYDIFYTGDFLQSYGIKVKIGNFFKYLTQPQKLLMFDEMVDWATDIRQTLPSICSTPCNPGFRKSPQEGKAVCCFDCNPCPENEISNMTDMDYCYKCLDNQYANSEGTHCLSKTVIFLSYEDPIGVTLACLALCFSALTAVVFGIFLRNQDTLIVKANNRALSYCLLISLIYCFLCSLLFIGKPHMVTCIMQQTIFAVAFTVAVSTVLSKTITVVLAFKFTLPSKKMRWLMTSGTSVLIIPICTMIQLIICGIWLGTYPPYVDSDGHIEHGHILIVCNKGSVTAFYCVLGYLGSIALASFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWLTFLPVYHSTSGKALVIVEVFCILTSTAGLLICIFAPKCYIILLTPKNNSFHTFRHNANVK", "length": 847 }, "evidence": [ { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PVI0-1", "protein_name": "Vomeronasal 2, receptor 34", "gene_name": "Vmn2r34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFIFMEVFFLLNITLLMANFIDPRCFWRINLDEIMDEYLGLSCAFILAAVQTPIENDYFNKTLNVLKTTKNHKYALALVFAMDEINRNPDLLPNMSLIIRYTLGRCDGKTVIPTPYLFRKKKESPIPNYFCNEETMCSYLLTGPHWEVSLGFWKHMNSFLSPRILQLTYGPFHSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYFSWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDDVSFPQNTEMYYNQIVMSSTNVIIIYGETYNFIDLIFRMWEPPILQRIWITTKQLNFPTRKTDISHGTFYGSLTFLPHHGVISGFKNFVQTWFHLRNTDLYLVMQDWKYFNYEDSASTCKILKNNSSNASFDWLMEQKFDMTFSENSHNIYNAVHAIAHALHEMNLQQADNQAIDNGKGASSHCLKVNSFLRRIYFTNPPGDKVFMKQRVIMQDEYDIVHFVNLSQHLGIKMKLGKFSPYLPHGRHSHLYVDRIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNETNMDQCVNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMSCFLCSFLFIGLPNRAICVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRNFLVSGTPNYIIPICSLLQCVLCAIWLAVSPPFVDIDEHTLHGHIIIVCNKGSVTAFYCILGYLACLALGNFSVAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGILGCIFVPKIYIILMRPERNSTQKIREKSYF", "length": 852 }, "evidence": [ { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW21-1", "protein_name": "Vomeronasal 2, receptor 74", "gene_name": "Vmn2r74", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFLNSVFWLLKISFNFGHLSDPRCFWRIKDTENKLGDKETYCFFTISTKHGYVKNDYFRWNLDKKVTPKTRHLIFSVYLALEEINKNCHILPNISLVVNIECVLDKHDEKTDFLFKSEDLIPNYYCKNERRYLIVLTAPLWAVSSSIGPYLFMSRIPEVSQLYCGHFHLPLSDNEQYPHLHQISRKDTFLPLAMVSLVVHFRWNWIGVIVTNDDHGIQFLSEFRGEMQNKIVCLSFAIIIKTGKFLAVTELHMNYKQILMSSAKVVIVYGYRDSPIIYAFIVWKSQDLFRIWVSVSQLDMITFLGDFLLYASTGTFIFSHQKPEISGFEQFIQRIHPSNYSSEFSLAKQWWTYFRCSLPPSNCKKLKNCSTKTVFKWLFMTPLGLAMSDTCYNIYNAMYAVAHSLHGMLLQQVDTWSKNAGKELEFDSWKMFSILKTLKFVNPAGDLVNMNQNLKQDVEFDVFYIMDFQKDYGLKMKIGRFSEHLPSGQQIYMSKEMIEWATDIDQILPSICTMPCRPGLRKSPQEGKDICCFDCKPCSENEVSNMTNMDQCVKCPEDQYANEDHTVCLQKVVTILDYRDPLGKALAGFALCFSVLTSLVLVVFLKHRDTPIVKANNQTLSFVLLISLIFCFICSLLYIGHPTMAICILQQTTFAIVFTVATSTILSKTVIVILAFKITVPGRRMRWLLESGTPKYIIPICTIIQLILCGIWLGTSPPFVDADLHMVHGHILIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYIILLRPQKNYFYKFRKRRELNLTT", "length": 853 }, "evidence": [ { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q067-1", "protein_name": "Vomeronasal 2, receptor 79", "gene_name": "Vmn2r79", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLTFVFLVLKLSFLFCYLSDPRCFWRIKDRENYLGDKEADCFFSMYTKHGYVKNDYFSENLDKKVTLKTIHLISSVYFAAEEINRNSYILPNTSLIVKIECNLIADNVKRIWSLKKKEIIPNYYCKNQRRYLIVLTGPIWITSYILGPFLYFSQTPELYCGHFHLLLNDQEQFPHLYQMTPKDTSLPQGMVSLAVHFRWNWVGVIITDDDHGIQFLSELRAGMESNTVCLAFVTIITYNRKLYLKMYHKYYHQITMSSAKVVIVYGDKESPLQFNFILWKSENIQRLWVSVSQFDIITMIGEFMLNSVHGTLIFSHQQSEMSGFKQFMQTVHPSNYSNDISLAKLWWTYFKCSLPPPDCKTLKNCPTKTLLKRFFVPPLGMSMSETCYNLYNSVYAVAHSLHEMLLQQVDTCSENDGKVLEFNSWKMFSFLKTIQFVNPVGDLINMNQNRERDTEYDIFYIMDFLKHEGLKMKIGRFSGHFPNGQQLFISDEMIEWATDIKQTIASACSVPCRPGLRKYFQEGKAVCCFDCYPCPENEISNMTDMDQCLKCPEDEYANTDQTNCLKKVVTFLDYKEPLGMALTGLAVLFSSLTVVVLCVFLKHRDTPIVKANNETLSYVLLISLIFCFICSLLYIGYPSMVSCILQQTTFAMVFTVSASCVLAKTITVVLAFKITVPGRRLRWLLLSGAPNYIIPICTTIQMMLCGIWLGISPPFVDADLHMVHGHIIIVCNKGSVIAFYCVLGYMGSLALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFLPVYHSTKGKAMVAVEVFCILASSAGMLLCIFVPKCYLILWRPQINSFHEFRKMHVKNKNIN", "length": 851 }, "evidence": [ { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q281-1", "protein_name": "Vomeronasal 2, receptor 114", "gene_name": "Vmn2r114", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLLADFISPRCFWKMKQNENRDRNQGTGCTFMIHAVQRPVEKEYFSHILNIQTHAENYKNVLALAFSIYEINRNPDILPNMSVRFTISKYNCYWESELMSLIHLSLQNHDILPNYMCKELTRCTMALTRLNWVTTVKLNTILNNFISQQFFQITYGPFHPVLSDHEKFPYLYQMASDHTSLALALVSFIIHFSWNWVGLAISDNDQGIQFLSYLRRVMEKNAVCFAFVNMIPMSMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQIAFQKFDLPKDNGKEHNYSCKKLYSFLRKTQFTNPVGDRVNMNQRDKLQEEYDIFYIWNFPQGLELRVKIGMFSPYFPNGQQVHLSEDMIEWAKGSAQMPTSVCSAECGPGSRKFRMDGMAACSFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNHCIRKTVVFLSYEEPLGVALSLISLFFSAVTIVVLGVIVKHHSTPVVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGVVFTVSVSTVLAKTITVVLAFKITASQRMMKYFLVSGAINYIIPFCILIQVIVCAVWLGASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGRVMVAVEIFSILASSAGMLGCIFVPKCYTILFRPDQNSLEMIRAKSSSRAHIS", "length": 856 }, "evidence": [ { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3F5-1", "protein_name": "Vomeronasal 2, receptor 76", "gene_name": "Vmn2r76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIDMFSFISVFLVLKASMLFCSLNEPKCFLRIKDKKNKDGDKEVDCFFSIYTKHGHMKNEHFSGNLDKQLTTKNIHLILSLYFAIEEINMSPHLLPNISLLVKVECKLLADGSKVSLSSRRGDYFPNYNCGNHRRYLIVLTGPMWLPTAMLGPLLYISRTPEVRRLYYGPFHPLLSSFEHFPYLYQIAIKDTSVAIGMVSLVIYFGWNWVGLMISDDGLGLQFASELREEMQRYDICLAFVTIITYNTKLFLTMTDTYYNQIMMSLAKAVIIFGDKDSLLQVIFRLWQFLDIRRIWVTTSQWDIITSNGEFLFNSFHGTLSFSHHYSEIAGFKEFIQTAHPLNYSNTISLAKLWWLNFNCFLSSSNCKSLKTCSRKMLLKWLSRNHFEMSMSDTSYNLYNAVYAVAHSLNELLLQQANTLSNNVGKGLEFDSLQVLSSLKNIHFVNPAGDLVNLNQKENMNINYDIFYTGNFLQSFGIKVKIGKFFKYFTHPQELLMYEELVDWATDVRQTLPSICSIPCHPGFRKSPQEGKAVCCFDCIPCPENEISNMTDMDYCFKCPDNQYANPEGTHCLSKIVTFLSYEDPMGVVLACLALGFSALTAAVFGIFLRNQDTPIVKANNRALSYCLLISLIYCFLCSLLFIGQPHILTCIMQQTIFAVVFTVAISTVLTKTITVVLAFRFTLPSKRMRWLMTSGASILIIPICTMIQLIICGIWLGTSPPFVDSDGHIEHGHILVVCNKGSVIAFYCVLGYLGSIALTSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWLTFLPVYHSTNGKALVAVEVFCILTSTAGIFLCIFAPKCYIILLKPENKSFHKFRHKNANV", "length": 853 }, "evidence": [ { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7F1X2-1", "protein_name": "Vomeronasal 2 receptor, 32", "gene_name": "Vom2r32", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFILMVVFFLLHHPLLMANFIDPWCFWRTNLNEVKEKNLDINCAFILGAVQLPMEKDYFNETLNVLKTTKNNKYALALAFSMEEINRNPDLLPNMSLVIKHTLSYCDGNTADHIFKEKFYKPLPNYVCNEETMCSFMLIGLNWVLSLTLFKDLDIFSFPRFLQISYGPFHSIFSDNEQFPYLYQMTPKDTSLALAIVSFLLYFNWNWVGLVISDNDEGNQFLSELKKETQNKEICFAFVNMMSIHEHSSYQKTEMYYNQIVMSSTNIIIIYGKTNSIIELSFRMWVSPVIQRIWVTNSELDFPTSMRDFTHGTFYGTLTFLHHHGEISGFTNFFETWDHLRSRDLNLLIPEWKYFSYDASGSNCKILRNYSSNASLEWITEQKFHMAFNDYSHSIYNAVYAMAHALHETNLQEVDNKEIRNGKGASTHCLKVNSFLRKTHFTNSHGERVIMKQRVRVQEDYDIVHIQNFSQHLRIKMKIGKFSPYFTHGGPFHLYEDMIQLATGSRKMPSSVCSADCSPGFRKSWKEGMAPCCFICSLCPENEISNETNMDQCVNCPEYQYANTEKNKCIQKDVIFLSYEDPLGMALALIAFCLSAFTAVVLWVFVKHHDTPIVKANNRILSYILIMSLMFCFLCSFFFIGHPNRGTCILQQITFGIVFTVAVSTVLAKTITVILAFKLRDPGRSLRNFLVSGAPNYIIPICSLLQCILCAIWLAVSPPFVDIDEHSEHGHIMIVCNKGSIMAFYCVLGYLACLALGSFTTAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTRGRVMVAVEIFSILASSAGMFGCIFAPKIYIILMKPERNSIQKFREKSYF", "length": 849 }, "evidence": [ { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3V911-1", "protein_name": "Vomeronasal 2 receptor, 75", "gene_name": "Vom2r75", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLILMVIFFLLNIPFLLANFMDPRCFWKINLNEIKDEVLGMTCSFILETVQKTMDKDYFNQTLNVLNTTTNHKYALALAFTVDEINRNPDLLPNMSLIIKYNLGHCDGKTVTTLSDLFNPNNHLHFPNYLCNEGIMCLVLLTGPHWRASLYLWISVYVYLSPHFLQLSYGPFYSIFSDNEQYPYLYQMGPKDSSLALAMVSFIIYFKWNWVGLFISDDDQGNQFLSELKKESQTKDICFAFVNMVSVSDVSYYHKTEMYYNQIVMSSTKVIIIYGETNSIIELSFRMWSSPVKQRIWVTTKQFDCPTSKRDLTHGTFYGTLTFLHHYGEISGFKNFVQTRYNLRSTDLYLVTPEWKYFNYEASASNCKILRNYLSNISLEWLMEQKFDMSFSDYSHNIYNAVYAIAHALHEKNLQEVENQAINNAKGENTHCLKLNSFLRKTHFTNSLGNRVIMKQREVVHGDYNIVHMWNFSQRLGIKVKIGQFSPHFPQGQQLHLYVDMTELATGSRKMPSSVCSADCHPGFRRIWKEEMAVCCFVCNPCPENEISNETNMDQCANCPEYQYANTEKNKCIQKGVIVLSYEDPLGMALALIAFCFSAFTVVVFWVFVKHHDTPIVKANNRILSYLLIVSLMFCFLCSFFFIGYPNRATCILQQITFGIFFTVAISTVLAKTITVVLAFKVTDPGRQLRIFLVSGTPNYIIPICSLLQCILCAIWLAVSPPFVDIDEHSEHGHIIIVCNKGSITAFYCVLGYLACLAFGSFTIAFLAKNLPDTFNEAKFLTFSMLVFCAVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKVYIILMRPDRNSIHKIREKSYF", "length": 852 }, "evidence": [ { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X931-1", "protein_name": "Vomeronasal 2, receptor 65", "gene_name": "Vmn2r65", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSFMSFFLILEYFLLLSVAHPKCFWRIKQNENKVGDVEDNCFFYIYTRQGPLLNDPFNGNPDILLTTRNIHLILALLFAIKQINRNIHILPNISLIVNVNCAKKEDLQMTNMYSNRDATIPNYNCKHGRRILTVLTGPRWFSSAILGPFLHIFAIPQLYYGPFHPLLSDREHYPYLYQMSPKNTFLTLAMTALVVYFSWNWVGLVISDDELGIEFLFKLRGEMHKHKVCIAFVNMIIQNIQLYQKRAEKYYNQILTSSAKVIIIYGDSDILTVHFRLWQHLGIKRLWITTSHWDENTSKGDLLLSSFNGIFIFSHPHSKIPGFKKFIQTVHPSNYSKDTSLARLWWLYFNCSLPSHCKTLKNCSTKILLEWLSRHQFEVSMSEPSYNLYNAVYAVAYALHEMLIQHTEHWQKDIGKELEFYSWKVAPFLENNKFIIPSEYQYRRGKLDTEYDILYAMDLLPALGLNVKIGKFSQHFLHFQQLYIAEDMIDWTIDIRQTLQSVCSVPCSVGFRKFIQKGKAVCCFDCTPCPENEISNMTDMDQCVKCPNDQYANIKQTHCLKKVVTFLAYEDPLGMTLTCLALLFSALTTVILSILLKHQDNPIVKANNRLLSYILLISLIFCFLCSLLYIGHPHMATCILQQTTFAVVFTVAVSTILAKTITVVMAFKITDPRKKIRQMLVTRAPNYIIPICTMIQLILCGTWIGTSPPFVDSDPHFEHGHIIIVCNKGSVIAFYCVLGYLGLLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTKGKAMVVVEIFSILTSSAGLLVCIFFPKCFTILLKQKVNFTQKFSDTHSKIEYNH", "length": 845 }, "evidence": [ { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3XA45-1", "protein_name": "Vomeronasal 2, receptor 69", "gene_name": "Vmn2r69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVIWFLKIKLMFCHLSDPSCFWRIKETENDLGDTETYCLFSISTKQGYVKNDYFSWNIDKKVTPKTNHLIFSVYLALEEVNKNCHILPNISLLVNIECNGRKYDEKTGLALKIENIIPNYSCTNERTYLIVLTAPIWAVSTKLGPFLFMSRIPELYCGHFHPLLSDNEEFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGVIVTSDDQGIQFLSELKGEMQKNIVCLSVAIIIQTEMSMALKELSMNYKHISISSAKVVIVYGDKFSPINYALTLWISQGILRIWVSVSQFDMITILGDFLLYSSTGTFIFSHQQPEIPGFEKFIQTVYPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKTIFTWLFRTPFGMAMSDTCYNSYNAIYAVAHSLHEMLMQEVDTWSNNAGKELEFDSWKMFSILKTLKFVNPAGDLVNMNQNLKQATQYNIFYVMDFQKDYGLKMKIGRFSEHLPSGQQLYMSKEMIEWATDIDQILPSICSMPCTPGLRKSPQEGKDICCFVCIPCPENEISNMTNMDQCVKCLEDQYANEDHTLCLQKVVAILDYRDPLGKALAGFALCFSLLTSVVLFVFLKHRDTPIVKANNQTLSIVLLISLIFCFICSLLYIGHPTMVICILQQTTFAIAFTVATSTILAKTITVVLAFKITVPGRRMRWLLVSGAPKYIILICTMIQLILCGIWLGTSPPFVDADVQMVHGHIIIVCNKGSVIAFYCVLGYMGSVALAGFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWMTFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYFILRPQTNSFHKFRKPHAKTENKS", "length": 850 }, "evidence": [ { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8Z7-1", "protein_name": "Vomeronasal 2, receptor 75", "gene_name": "Vmn2r75", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNTFSLISVFWFLKISIIFCHLSDPRCFWRIKDAKNDLGDKETYCFFSIYTKQGYVKNDYFSWNLDKKVTPKTNHLIFSVYLAMEEINKNGHILPNISLLVNIECGLELYGERTGLAFKSEEFIPNYYCRNHRKYLIVLTTPKWGVSTSLGPLLYISRVPELYCGHFHLLLNDNEQFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGAIVTNDDHGIQFLSELRGEMQKHIVCLSVAIIIQTEKFMALKEFRMNYNKIAMSSATVVIVYGDKDSPIQFTLIMWKSEGIWRIWVSVSQFDMITVIGDFLLYSSTGSFIFSHQQSEISGFEKFIQTVHPSNYSSEFSLAKLWWTYFTCSLPPSNCKKLKNCPIKTVFKWLFMTPIGMSMSDISYNLYNAMYAVAHSVHEMLLQQVDIWSTNAGTELEFDSWKMFSILKTLKFVNPAGDLVNMNQNLKQDTEYDIFYIPNFQKYYGLKMKIGRFSGYLPSGQQLYMSKEMMEWATDMDQILPSICSMPCRPGLRKSPQEEKDICCFVCNPCPENEISNMTNMDQCVKCPEDQYANEDQTLCLQKVVDVLDYRDPLGKSLAGFALCFSVLTSIVLCVFLKHRESPIVKANNQTLSYVLLISLIFCFICSLLYIGHPTMFICILQQTAFAIAFTVAASTVLAKTITVILAFKITVPGRMRWLLVSGAPKYIIFVCTMIQLIFCGIWLGTSPPFVETDVHMTHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLSRKLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIYAPKCYIILLRPQKNSFYKFRKPHSKSENIS", "length": 853 }, "evidence": [ { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N686-1", "protein_name": "Vomeronasal 2, receptor 32", "gene_name": "Vmn2r32", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFIFMGVFFLLNITLLMANFIDPRCFWRINLDEITDEYLGLSCAFILAAVQTPTEKDYFNKTLNFLKTTKNHKYALALVFAMDEINRYPDLLPNMSLIIRYSLGHCDGKTVTPTPYLFHRKKQSPIPNYICNEESMCSFLLSGPNWDESLSFWKYLDSFLSPHILQLSYGSFSSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYLKWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDEVSFPQKTEIYYKQIVKSLTNVIIIYGETYNFIDLIFRMWEPPILQRIWITTKQLNFPTSKTDISHDTFYGSLTFLPHHGEISGFKNFVQTWFHLRNTDLYLVMPEWKYINSEDSASNCKILKNSSSDASFDWLMEQKLDMAFSDNSHNIYNVVHAIAHALHEMNLQQADNQAIDNGKGASSHCLKVNSFLRRTYFTNPLGDKVFMKQRVIMQDEYDIVHFANLSQHLGIKMKLGKFSPYLPHGRHSHLYVDMIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNETNMDQCVNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMFCFLCSFFFIGLPNKVICVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRYFLVSGTLNYIIPICSLLQCVLCAIWLAVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTLAFLAKNLPDAFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGMLECIFVPKIYIILMRPERNSTQKIREKSYF", "length": 852 }, "evidence": [ { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T2-1", "protein_name": "Vomeronasal 2, receptor 67", "gene_name": "Vmn2r67", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKISFMFCHLSDPKCFWRIKDTKKNLGDTETYCSFSISTKRGYVKNDYFSWNLDKQVTPKTNHLIFSVYLALEEINMNFHILPNISLVVNIECLRKKYDEKTGLALQTEEFIPNYYCTDERRYLIIFTAPIWAVTTRLGTFMFMYSIPELYCGHFHLSLSDNEQFPHLYQISPKDTSLPLAMVSLMVHFRWNWIGAIVTTDDHGIQFLSELRGEMQKHIVCLSFEITILTEHSMARKEFQRYFNRIVMSSAKVVIVYGDYTSPIDLVLHLCKSKGIFRIWVSVSQFDMITKLGDFMLYSSSGTFIFSHQKPELSGFQQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKIVFKWLFMTPLGMAMSDTCYNLYNAIYAVAHSLHEMLLQQIDTWSNNAGKELEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTDYDIFYIMDFQKDYGFKMKIGRFSGHLPSHQQLYMSKEMMEWATDVDQILPSICSMPCRPGLRKSPEEGKDICCFVCNPCHENEISNMTNMDQCVKCQEDQYANEDHTLCLQKVVSILDYRDPLGKALAGIALCFSVLTSGILCIFLKHRETPIVKANNQTLSYVLLISLVFCFICSLLYIGHPTTVICILQPITFAIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLLSGVPKYIVLICTMIQLILCGIWLGTSPPFVDADVYMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFSILASSAGLLLCIFAPKCYIILLRPQTNSFHKFRKTHSKAENIS", "length": 851 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U5-1", "protein_name": "Vomeronasal 2, receptor 78", "gene_name": "Vmn2r78", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLIVVFLLLKLSFLFCSLSDPRCFWRIKDRENDLGDKETDCFFSIYTKRGYVKNDYFSENLDKKVTLKTIHLISSVYFAAEEINKNIYILPNISLIVKIECNLIADNVKRIWSLKKKEIIPNYYCKNQRRYLIVLTGPIWITSYILGPFLYFSQTPELYCGHFHFLLNDQEQFPHLYQMTPKDTSLPQGMVSLAVHFRWNWVGVIITDDDHGIQFLSELRTGMESNTVCLAFVTIITYNRMLYLKMYHKYYHQITMSSAKVVIVYGDKESPLQFNFILWKSENIQRLWVSVSQFDMITVIRDFMLNSLHGTLIFSHQQSEISGFKQFMQTVHPSNYSNDISLAKMWWTYFKCSLKPPDCKTLKNCPTKTLFKWFFVPPLGMSMSETCYNLYNSVYAVAHSLHEMLLQQVDTCSENDGTVMEFNSWKMFYFLKTIQFVNPAGDLINMNQNRERDTEYDIFYIMDFLKHEGLKMKIGRFSGHFPNGQQLFMSDEMIEWATDIKQTLASACSVPCRPGLRKYFQEGKAVCCFDCYPCPENEISNMTDMDQCVKCPEDEYANTDQTNCLKKVVTFLDYKEPLGMALAVLAVFFSSLTFIILCVFLKHRDTPIVKANNETLSYVLLTSLIFCFICSLLYIGYPTMVSCILQQTTFALVFTVAASCVLAKTITVVLAFKITVPGRRLRWLLLSGAPNYIIPICTTIQMILCGIWLGTSPPFVDADLHMIHEHIIIVCNKGSVTAFYCVLGYMGSLALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWVTFLPVYHSTKGKAMVAVEVFCILASSAGMLLCIFVPKCYLILLRPQINSFHEFRKIHAKSININRM", "length": 853 }, "evidence": [ { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6V1-1", "protein_name": "Vomeronasal 2, receptor 117", "gene_name": "Vmn2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLVSDFIYPRCFWKIKQNEDKNRNQGTECTFMIHAVQRPVEKEYFSHILNIQTHTENHKYALALAFSIYEINRNPDILPNMSLTFKFSNYNCHWKSKYNSFIHLSLQNHDILPNYMCKEFTKCAMALTRLNWATTVKLNTILNNFMSQQFLQITYGPFHPVLSDHEKFPYLYQMASDHTSLALALVSFIIHFSWNWVGLVISDNDEDIQFLSYLRREMEKNTVCFAFVNMIPMSMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQIAFQKLDNLPKDNGKEHNYSCKKLYSFLRKTQFTNPVGDRVNMNRRNKLQEEYDIFYIWNFPQGLGLRVKIGMFSPYFPNGQQVHLSEDMIEWAKGSAQVPTSVCSAECGPGSRKFRMDGMAACCFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNQCIRKTVVFLSYEEPLGMALSLLSLCFSAFTTVVLGVMVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGVVFTVSVSTVLAKTITVVLAFKITASQRMMKYFLVSGAINYIIPICILIQVIVCAVWLRASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYYSTKGKVMVAVEIFSILASSAGMLGCIFVPKCYTILFRPDQNSLEMIRVKSSSNAHVS", "length": 857 }, "evidence": [ { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N702-1", "protein_name": "Vomeronasal 2, receptor 70", "gene_name": "Vmn2r70", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLNSVFWFLKISFIFCHLSDPRCFWRIKDTENNIGDTETYCFFSISTKHGYVKNDYFSWNLDKQVTPKTRHLIFSVYLALEEINDSFHILPNISLVVNIECVLQKYGEKTGLLLRSEKLIPNYYCINERRYLIVLTAPTWAISTKLGPFLFMSRIPEVNQLYCGHFHLPLSNNEQFPHLYQISKKDTSLPLAMVSLVVHFRWNWIGVIITNDDHGIQFLSELRGEMQNNIVCLSVVITIKTQKLVALKELHMNYKQILMSSAKVVIVYGYKDSPIIYALISWKSHGIFRIWVSVSQFDMITIRGDFLLYSSTGTFIFSHQKPEISGFEQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSDCKKLKNCPTKTVFKWLFMTPLGMAMSDTCYNLYNAVYGVAHSLHEMLLQQVDAWSKNAGKELEFDPWKMFSVLKTIQFINPAGDLVNMNQNLRQDVEYDVFYIMDFQKVYGLKMKIGRFSGQLSSGQQLYMSKEIIEWATDIDQILPSICSMPCRPGLRKSPQEEKDICCFGCNPCPENEISNMTNMDQCVKCPENQYANEDHTLCLEKVVAILDYKDPLGKALAGFALCFSVLTSVVLGIFLKNRDTPIVKANNQSLSFVLLISLIFCFICSLLYIGHPTMVICILQQTTFAIVFTVATSTILAKTVIVVLAFKITVPGRRMRWLLEIGAPKYIILICTIIQLILCGIWLGTSPPFVDADVHMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFSILASSAGLLLCIFAPKCYIILLKPQKNSFQKFRKPHAIADNIS", "length": 854 }, "evidence": [ { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N741-1", "protein_name": "Vomeronasal 2, receptor 36", "gene_name": "Vmn2r36", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFIFMGVFFLLNITLLMANFIDPRCFWRINLDEITDEYLGLTCAFILAAVQTPTEKDYFNKTLNFLKTTTNHKYALALVFAMDEINRNPDLLPNMSLIIRYALGHCDGKTVTPTPYLFHKKKKSPIPNYFCNEESMCSFLISGPNWKVSLSFWKYLDSFLSPRIFQLTYGPFSSIFSDDEQYPYLYQMAPKDTSLALAMVSFIHYFNWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDDVSFPQNTEMYYNQIVMSSTNVIIIYGETYNFIDLIFRMWEPPILQRIWITTKQLNFPTRKKDISHGTFYGSLTFLPHHGEISGFKNFVQTWFHFRNTDLYLVMPEWKYFNYEDSASNCKILKNNSSDASFDWLMEQKFDMTFSESSHNIYNAVHAIAHALHEMNLQKADNQAIDNGKRASSHCLKVNSFLRRAYFTNPLGDKVFMNQRVIMQDEYDIIHFWNLSQHLGIKMKLGKFSPYLPHGRHSHLYVDMIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNETNMDQCMNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMFCFLCSFFFIGLPNRAICVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRNFLVSGTPNYIIPICSLLQCVLCAIWLAVSPPFVDIDEHTLHGHIIIVCNKGSDTAFYCILGYLACLALGSFSLAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGILGCIFVPKIYIILMLPERNSTQKIREKSYF", "length": 852 }, "evidence": [ { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B3-1", "protein_name": "Vomeronasal 2, receptor 68", "gene_name": "Vmn2r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVIWFLKVKLMFCHLSDPKCFWRIKDTENNLGDTETYCSFSISTRHGYVKNDYFSWNLDKKVTPKTNHLIFSVYLALDEINMNIHILPNISMVANIECFLQKDGEKTGLALQRKEFIPNYYCTDERRYLIIFTAPIWAVTTRLGPLMFMYSIPELYCGHFHLSLNDNEQFPHLYQISPKDTSLPLAMVSLMVHFRWNWIGAMITNDDHGIQFLSKLRGEMQKHIVCLSFVITILTEHSMAHKEFQRYFNRIVMSSAKVVIVYGDYTSPIDLVLHLCKSKGIFRIWVSVSQFDMITYLGDFMLYSSSGTFIFSHQKPELSGFQQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPFNCKKLKNCPTKIVFKWLFMTPLGMAMSDTCYNLYNAIHAVAHSLHEMLLQQVDTWSNNAGKELEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTEYEIFYIMDFQKDYGLKMKIGRFSGHLPSRQQLYMSKEMMEWAIDVDQILPSICSMPCRPGLRKSPQEEKDICCFVCNPCLENEISNMTNMDQCVKCREDQYANEHHTLCLQKVVSILDYRDPLGKALAGIALCFSFLTSVVLCIFLKHRETPIVKANNQTLSYVLLISLVFCFICSLLYIGHPTAVICILQQTTFVIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLVSGAPKYIILICTMIQLILCGIWLGTSPPFVDADAHMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYIILLRPDINSFQKFRKPHANAENIS", "length": 851 }, "evidence": [ { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B5-1", "protein_name": "Vomeronasal 2, receptor 45", "gene_name": "Vmn2r45", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFIFMEVFFLLNITLLMANFIDPRCFWRINLDEIMDEYLGLSCAFILAAVQTPIENDYFNKTLNVLKTTKNHKYALALVFAMDEINRNPDLLPNMSLIIRYSLGHCDGKTVIPTPYLFRKKKESPIPNYFCNEETMCSYLLTGPHWEVSLGFWKHVNSFLSPRILQLTYGPFHSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYFSWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDDVSFPQNIEMYYNQIVMSSTNVIIIYGETYNFIDLIFRMWEPPILQRIWITTKQLNFPTRKTDISHGTFYGSLTFLPHHGVISGFKNFVQTWFHLRNTDLYLVMQEWKYFNYEDSASTCKIKKNNSSNASFDWLMEQKFDMTFSENSHNIYNAVHAIAHALHEMNLQQADNQAIDNGKGASSHCLKVNSFLRRIYFTNPPGDKVFMKQRVIMQDEYDIVHFVNLSQHLGIKMKLGKFSPYLPHGRHSHLYVDMIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNETNMDQCMNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMFCFLCSFFFIGLPNRAICVLQQITFGIVFTVALSTVLAKTVTVVLAFKVTDPGRRLRNFLVSGTPNYIIPICSLLQCVLCAIWLAVSPPFVDIDEHTLHGHIIIVCNKGSVTAFYCILGYLACLALGSFSVAFLAKNLPDAFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGILGCIFVPKIYIILTRPERNSTQKIREKSYF", "length": 852 }, "evidence": [ { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B7-1", "protein_name": "Vomeronasal 2, receptor 77", "gene_name": "Vmn2r77", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEMFSLIVFFLVLKLSFLFCYLSDPRCFWRIKDRENYLGDKEADCFFSIYTKRGYVKNDYFSENLDKKVTLKTIYLISSVYFAIEEINRNIHILPNISLLVKIDCNLIEDNVERVWSLKKKEIIPNYYCKNQRRYLIVLTGPIWITSYILGPFLYFSRTPELYCGYFHLLLSDQEQFPHLYQMTPKDTSLPLAMVSLAVHFRWNWVGVIITDDDHGIQFLSELRTGMERNTVCLAFVTSITYDKMLYLKMTHKYYHQIIMSSAKVVVVYGDKESPLQLNFMLWKSINIQRLWVSVSQFDMITMMGDFMLNSIHGTLIFSHQQSEMSGFKHFIQRVNPSNYSNDISLAKLWWTYFKCSLPPPDCKTLKNCPTKTLFQWFFEPPLGMSMSETCYNLYNSVYAAAHSIHEMLLQHVDTSSENDENVLEFNSWKMFSFVKNIQFVNPAGDLVNMNQNRKLDTEYDIFYITDFLKHEGLKMKIGRFSGHFPNGQQLFISDEMIEWATDIKQTLASICSVPCRPGLRKYFQEGNSVCCFDCYPCPENEISNMTDMDQCVKCPEDEYANTNQTKCFKKVVTFLAYEDPSGMALAVLAVCFSVLTSVVLCVFLKHRNTPIVKANNETLSYVLLTSLIFCFICSLLYIGYPTMVSCILQQTTFAIVFTVAASCVLAKTITVVLAFKITVPGRRLRWLLLSGAPNYIIPICTMIQMILCGIWLGTSPPFVDADLHMVHGHIIIVCNKGSVIAFYCVLGYMGSLALSSFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFLPVYHSTKGKAMVAVEVFCILASSAGMLVCIFLPKCYIILLRPQINSFHDFRKIHVKVININ", "length": 854 }, "evidence": [ { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2D8-1", "protein_name": "Vomeronasal 2, receptor 71", "gene_name": "Vmn2r71", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKVNFIFCHLSDPRCFWRIKETENKLGDKETFCLFSISTKQGYVKNDYFSWNLDKQVTPKINHLIFSVYLALEEINKNCHILPNISLLVNTECNGRKYDEKTGLALKSEKIVPNYSCTNERRYLIVLTAPIWAVSTKLGPFLYISRIPELYCGHFHLLLSDKGQFPHLYQISPKDTSLPLAMVSLFVHFRWNWIGVIITNDDHGIQFLSELKGDMQKSIVCLSVAIIIQTEVYMALKELHMNYKKILMSSAKVVIVYGDKDSPIKYVLTAWKSQGIFRIWVSASQFDMITILGDFLLYSYTGTFIFSHQQPEIPGFEKFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKSVFAWLFRTPLGMAMSDTCYNSYNAIYAVAHSLHEMLLQEVDTWSKNAGKELEFDSWKMFSILKTLKFVNPSGDLVNMNQNLKQDTEYDIFYIMDFQKDYGLKMKIGRFSGHLLSGQQLYMAKEMMEWATDIDQILPSICSVPCSPGLRKSPQEGKDICCFVCNPCPENEISNMTNMDQCVKCLEDQYANEDHTLCLQKVVVIFDYRDPLGKALAGFALCFSVLTSVVLFVFFKHRDTPIVKANNQTLSFVLLISLIFCFICSLLYIGHPTMVTCIVQQITFAIGFTVATSTILAKTVIVVLAFKITVPGRRMRWMPESGAPKYIILICTMIQLILCGIWLGTSPPFVDADVQMVHGHIIIICNKGSVIAFYCVLGYMGSLALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKIMAVVEVFCILASSAGLLLCIFAPKCYIILLRPQTNYFHKFWKSHANSENKS", "length": 851 }, "evidence": [ { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060503-735", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-735#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1LV89-1", "protein_name": "Olfactory receptor CQ3 precursor", "gene_name": "olfcq3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLNICLHLSFIFISVNSDSCQIQGHFKLNRMYKDGDYIIGGLFEVQHLKVFPELSFRMEPEQPKCEEFYMSSFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCLKLVVAFRAATTLISGTEETFSNFNCTGPPPVIAIVGDPGSTHSIAVSSVLGLFHVPLISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMVQILKYFGWTWVGVLYSDDDYGIYAAQSFQQEMQRFKGCVAFSEIVPYDNHRDIQRIVAVIKASTARVVVAFSTDLLPLMEELLQQNVTGRQWIASEAWSTSPVLHLPRFVPLVRGTLGIAIHRGKIKGLHEFLLHIQPDNDPTNNMVRIFWENMFGCSFEKGNGYGEKMCTAQEDLNITVNEYNDVSELRASYNVYKAVYALAHALHDLMQCEEGRGPFSGNSCADITKLKPWQMVPYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWHPSSDGLIVVRTVGVVDEGASAGRVLTLDEDAIYWNFETKKPPRSVCSESCPPGTRRAMRKGLPVCCFDCLPCADGEISNMSDATECTSCPNEFWSSPKKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVLAVFAHHHNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAMFGISFVLCVSSILVKTMVVIAVFKSSRPEGKSAVKWFGAVQQRGTVLVLTAVQIVICVVWLSTASPTPHKNILYVRSKIVFECSIGSMAGFAILLGYIGILAAVSFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFIPAYVSSPGKYSVAVEIFAILASSFGLLVAIFVPKCYIIILHPERNTKKAIMGRTAEK", "length": 855 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVL1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVL1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVL1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVL1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 588, "end_pos": 590, "annotation": "n_glycosylation_sequon" }, { "start_pos": 659, "end_pos": 661, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UVL1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVL1" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 625, "end_pos": 890, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 170, "end_pos": 172 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 588, "end_pos": 590 }, { "start_pos": 659, "end_pos": 661 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVM2-1", "uniprot_ac": "A0A8N7UVM2", "uniprot_id": "A0A8N7UVM2_DANRE", "mass": { "chemical_mass": 66194.0, "monoisotopic_mass": 66194.0 }, "refseq": { "ac": "XP_697785", "name": "neuronal pentraxin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697785" }, "gene_names": [ { "name": "si:dkey-283b15.2", "type": "recommended", "evidence": [ { "id": "A0A8N7UVM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVM2" } ] }, { "name": "si:dkey-283b15.2", "type": "synonym", "evidence": [ { "id": "XP_697785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697785" } ] } ], "protein_names": [ { "name": "Neuronal pentraxin-2", "type": "synonym", "evidence": [ { "id": "A0A8N7UVM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVM2/entry#names_and_taxonomy" } ] }, { "name": "neuronal pentraxin-2", "type": "synonym", "evidence": [ { "id": "XP_697785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697785" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On May 12, 2025 this sequence version replaced XP_697785.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_697785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697785" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVM2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVM2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-283b15.2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVM2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100921-93", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100921-93", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVM2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UVM2", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00152", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00152", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "569313", "url": "https://www.ncbi.nlm.nih.gov/gene/569313", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051360", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051360", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569313", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569313", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UVM2", "url": "https://www.orthodb.org/?gene=A0A8N7UVM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19277:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19277:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_697785", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697785", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVM2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100921-93", "url": "https://zfin.org/ZDB-GENE-100921-93", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRSPISLRKTALFFLVCFFSACSGTGIPGSDYNPHPRFICTPIPADADPGCFPSAGGPSAGHHSGPSSGGSNSWWGISEEAKTTILHLRESLVQQKETILDQRETIRELTAKLNLCEGFNRGVGNHDDHPHRTPTHLAHHAHHAYPTAPEPGHLAWAPPPDAHHGGHGLELGHYEDAAHHRGKAAVSEKHVTGEIPLLSSTPEQMSRMLETLKERLENLQTRNTSASYSSSLKDLLQRKISALEQQMQHHSSPLTGASHTDHTEHDDGHHDDEDHDHGHHEDGHDERDHGDPHDDSHHSDRHEDGHHDDDHDDGHHDNDDHDAGHHDNGDHDDDHHDNGHHDNEVSEHGFERLLYNPQGHRESQTGAHSKLDAVLNQLQHRLTEGPRKKTKSTEAFQIGFPMRTNYMYGRVKRTLLHEIFSFTLCLWMKAGIGPGLGTPFSYSVPGQANELVLIEWGNNPMELLVDDKAVTLPLSLSDGKWHHVCVTWSTRDGLWEAYQDGVKRGSGENLSPWHPIKPGGVFILGQEQDTLGGRFDATQAFVGEISDVQMWSQVLTPHDVYSLASCGGHMTGDIIAWSEATVELHGGVTKYPFDPCH", "length": 597, "header": "tr|A0A8N7UVM2-1|A0A8N7UVM2_DANRE Isoform 1 of Neuronal pentraxin-2 OS=Danio rerio OX=7955 GN=si:dkey-283b15.2 PE=4 SV=2 CANONICAL=A0A8N7UVM2-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVM2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVM2/entry#A0A8N7UVM2-1", "sequence": { "sequence": "MRSPISLRKTALFFLVCFFSACSGTGIPGSDYNPHPRFICTPIPADADPGCFPSAGGPSAGHHSGPSSGGSNSWWGISEEAKTTILHLRESLVQQKETILDQRETIRELTAKLNLCEGFNRGVGNHDDHPHRTPTHLAHHAHHAYPTAPEPGHLAWAPPPDAHHGGHGLELGHYEDAAHHRGKAAVSEKHVTGEIPLLSSTPEQMSRMLETLKERLENLQTRNTSASYSSSLKDLLQRKISALEQQMQHHSSPLTGASHTDHTEHDDGHHDDEDHDHGHHEDGHDERDHGDPHDDSHHSDRHEDGHHDDDHDDGHHDNDDHDAGHHDNGDHDDDHHDNGHHDNEVSEHGFERLLYNPQGHRESQTGAHSKLDAVLNQLQHRLTEGPRKKTKSTEAFQIGFPMRTNYMYGRVKRTLLHEIFSFTLCLWMKAGIGPGLGTPFSYSVPGQANELVLIEWGNNPMELLVDDKAVTLPLSLSDGKWHHVCVTWSTRDGLWEAYQDGVKRGSGENLSPWHPIKPGGVFILGQEQDTLGGRFDATQAFVGEISDVQMWSQVLTPHDVYSLASCGGHMTGDIIAWSEATVELHGGVTKYPFDPCH", "length": 597, "header": "tr|A0A8N7UVM2-1|A0A8N7UVM2_DANRE Isoform 1 of Neuronal pentraxin-2 OS=Danio rerio OX=7955 GN=si:dkey-283b15.2 PE=4 SV=2 CANONICAL=A0A8N7UVM2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:569313", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569313", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1N943-1", "protein_name": "Neuronal pentraxin receptor b", "gene_name": "nptxrb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKFVVVIVSAGLLAFLGAVICIIASVYRRSSAAAPQGLSDNRSLSLLEPLPGSVAHAGPLGALHGAESYEGEGLDIGLEIPSINELSTGDVTRPSPKQFTLNRLICTPVPLSDCKSRGLREQSDDAFAEEEDWSLRTTAEELRQIVMQQNDQILMDQRTITELTGKLSECENGLEERTLNERSMGVWAGGRRHMAGDDVSGSVAVQLQTARAVEELERAILQLKDRIEKLEMEIGPAAINHTEHTVSTLGSIVVGEPGRPVEDLEGELEKKIRLLEKERKNLRKETQSHHQHIDQGINTLQERIAELEQSLTDYSYPQGYKLSFPVRTNYMYGLVRRNIPEMYAFTACLWLKPAESGIGTPFSYAVPEQPNQLVLLQGIHNPAELLINDKVAQLPLSLPKGIWQHICVSWTLRDGVWKAYQGGKMRGRGDGLSAWHPIKSGGVLVLGQEQDTLGGRFDASQALVGELSLFNLWDRVLSPTEVAALASCAESPRLGNVVPWTDRDVDVFGGAVKDPVDPCIKSSHPRQ", "length": 527 }, "evidence": [ { "id": "FB:FBgn0024897", "url": "https://alliancegenome.org/gene/FB:FBgn0024897#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BBR8-1", "protein_name": "Neuronal pentraxin-2a isoform X1", "gene_name": "nptx2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRALFVALLLVYASGSGKVAGANGAKGNRFVCTAVPAGTDLSCPVETTNRVQSTSPQEEELRNTIIQLRETILQQKETIVSQQGTIKELNSKLARCEADVRSRGSARRKDYSKNTMGDLPRDPTESVEQLGKTMQSLKDRLESLEQQLRTNTSNGAFPSELRDLLKRRLSDLEGQLLTRVAELEEEKSQLYNETAAHRQRTENTLNSLLERITELEKSNSAFKSPEDFKVALPLRTNYLYGRIKKSLPEMYAFTVCMWLKSSASPGIGTPFSYGVPGQANEIVLIEWGNSPMELLVNDKVAQLPLSVSDGRWHHICITWTTRDGFWEAYQDGERLGTGENLAPWHPIKPGGVIILGQEQDIVGGRFDATQAFVGELSHFNMWDRVLRPIDISAMANCSAYMPGNVVPWVDANVEVFGGATKAALEICEERLFDS", "length": 434 }, "evidence": [ { "id": "FB:FBgn0024897", "url": "https://alliancegenome.org/gene/FB:FBgn0024897#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32U432-1", "protein_name": "Neuronal pentraxin-2b isoform X1", "gene_name": "nptx2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLHLIAGLICVYGLTCVKVVYGQTEKGERFLCTAVPIDQDTSCPVPVPSASLQEEELRNTVMQLRETILQQKETIVNQLGTIKELTSKLSRCESESEIFRKMNKDTMDDVPKDPNDTIDVLGKTMQGLKDRLENLEQQQMRANASGASFPNELRNLLQHRLEDLENQLLKKVNELEEEKSQLYNETVAHRQRTDNTLNSLMNRISELEKGGAGFKSPENFKISLPLRTNYLFGQVKKSLPEMYAFTICMWLKSGSSPGIGTPFSYGVPGQANEIVLIEWGHNPIELLINDKVAQLPLSLSDGRWHHVCITWTTRDGLWEAYQDGQRLGSGENLAPWHPIKPGGVLILGQEQACRLWPQQDVVGGRFDATQAFVGELSHFNIWDRVLRSTDIITMANCSSYMPGNVVSWTDSNIEVFGGASKGPLELCEDRLFDN", "length": 434 }, "evidence": [ { "id": "FB:FBgn0024897", "url": "https://alliancegenome.org/gene/FB:FBgn0024897#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "O70340-1", "protein_name": "Neuronal pentraxin-2", "gene_name": "Nptx2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLALLTVGVALAVAAGRAQDSPIPGSRFVCTALPPEAARAGCPLPAMPMQGGALSPEEELRAAVLQLRETVVQQKETLGAQREAIRELTGKLARCEGLAGGKARGTGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLESLELQLRTNVSNAGLPSDFREVLQRRLGELERQLLRKVAELEDEKSLLHNETSAHRQKTESTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLPLFVSDGKWHHICITWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIINIANCSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL", "length": 429 }, "evidence": [ { "id": "FB:FBgn0024897", "url": "https://alliancegenome.org/gene/FB:FBgn0024897#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P47972-1", "protein_name": "Neuronal pentraxin-2", "gene_name": "NPTX2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLALLAASVALAVAAGAQDSPAPGSRFVCTALPPEAVHAGCPLPAMPMQGGAQSPEEELRAAVLQLRETVVQQKETLGAQREAIRELTGKLARCEGLAGGKARGAGATGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLESLEHQLRANVSNAGLPGDFREVLQQRLGELERQLLRKVAELEDEKSLLHNETSAHRQKTESTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLPLFVSDGKWHHICVTWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIVNIANCSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL", "length": 431 }, "evidence": [ { "id": "FB:FBgn0024897", "url": "https://alliancegenome.org/gene/FB:FBgn0024897#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P97738-1", "protein_name": "Neuronal pentraxin-2", "gene_name": "Nptx2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLALLTAGVALAVAAGQAQDNPIPGSRFVCTALPPEAARAGCPLPAMPMQGGALSPEEELRAAVLHWRETVVQQKETLGAQREAIRELTSKLARCEGLAGGKARGTGATGKDTMGDLPRDPGHVVEQLSRSLQTLKDRLESLELQLHTNASNAGLPSDFREVLQRRLGELERQLLRKVAELEDEKSLLHNETSAHRQKTENTLNALLQRVTELERGNSAFKSPDAFKVSLPLRTNYLYGKIKKTLPELYAFTICLWLRSSASPGIGTPFSYAVPGQANEIVLIEWGNNPIELLINDKVAQLPLFVSDGKWHHICITWTTRDGMWEAFQDGEKLGTGENLAPWHPIKPGGVLILGQEQDTVGGRFDATQAFVGELSQFNIWDRVLRAQEIINIANCSTNMPGNIIPWVDNNVDVFGGASKWPVETCEERLLDL", "length": 432 }, "evidence": [ { "id": "FB:FBgn0024897", "url": "https://alliancegenome.org/gene/FB:FBgn0024897#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q15818-1", "protein_name": "Neuronal pentraxin-1", "gene_name": "NPTX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPAGRAARTCALLALCLLGAGAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSSVLQLRETVLQQKETILSQKETIRELTAKLGRCESQSTLDPGAGEARAGGGRKQPGSGKNTMGDLSRTPAAETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDELERQVLSRVNTLEEGKGGPRNDTEERVKIETALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSATPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGSGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSTKALSGNVIAWAESHIEIYGGATKWTFEACRQIN", "length": 432 }, "evidence": [ { "id": "FB:FBgn0024897", "url": "https://alliancegenome.org/gene/FB:FBgn0024897#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62443-1", "protein_name": "Neuronal pentraxin-1", "gene_name": "Nptx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLAGRAARTCALLALCLLGSGAQDFGPTRFICTSVPVDADMCAASVAAGGAEELRSNVLQLRETVLQQKETILSQKETIRELTTKLGRCESQSTLDSGPGEARSGGGRKQPGSGKNTMGDLSRTPAAETLSQLGQTLQSLKTRLENLEQYSRLNSSSQTNSLKDLLQSKIDDLERQVLSRVNTLEEGKGGPKNDTEERAKIESALTSLHQRISELEKGQKDNRPGDKFQLTFPLRTNYMYAKVKKSLPEMYAFTVCMWLKSSAAPGVGTPFSYAVPGQANELVLIEWGNNPMEILINDKVAKLPFVINDGKWHHICVTWTTRDGVWEAYQDGTQGGNGENLAPYHPIKPQGVLVLGQEQDTLGGGFDATQAFVGELAHFNIWDRKLTPGEVYNLATCSSKALSGNVIAWAESQIEIFGGATKWTFEACRQIN", "length": 432 }, "evidence": [ { "id": "FB:FBgn0024897", "url": "https://alliancegenome.org/gene/FB:FBgn0024897#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V3N9-1", "protein_name": "B6", "gene_name": "b6", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAQRLHLALVGVVLLNATASFAWKPIVGGGSGISGGTAAYSLKQSHPGAASSSHEISTSFSQFGGDKETTEVEDELLLGRAAIVNGVDSSAAVSHPISFADHLEDQYESYSIEDEAPKEPLAFPRSPVYGSDRCSVKKFAFNQDGEVEYGNPMPELDQFTICFWMRFTNHSGDHVLLTYEAGKEPREVQIWVANAQNSSFLSMAIKGQQMYRLNYPLKMRQWHHMCSSWNGKTGEWQAWLKAERIGRGFHNSLVGHKIPANGKLRSGGSSVTGEVSHGLHFEMTLVQVYRVALSAGKAHRDHKHHHVHHFDHEGQEVSSTTRAPPSINRPQPMHTLLASGQIPTRVRINLANPPPTASGAPAPGAAGAPTDSAQQAITINTNFVNGQINAGSRLVAQQLLGLSPPSGLQPSGGGKRFQMLSNSANVQFIDETETHIQFKRNTDATKKVQKRGLVLLDDGSVVDDGVGSGTDGSLIYNGLADFGGQQFKQDLTLKMSLEEEISTHDREPAEEEVRAVMAICSSCHTEPFQGAIVFSWKDVREHMNNALKGLSVGPCGNF", "length": 558 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-100921-93", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100921-93#orthology", "database": "AGR" }, { "id": "FB:FBgn0024897", "url": "https://alliancegenome.org/gene/FB:FBgn0024897#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVM2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVM2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 509, "end_pos": 511, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UVM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVM2" }, { "id": "PS51828", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51828" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pentraxin (PTX)", "eco_id": "ECO_0000259", "start_pos": 394, "end_pos": 596, "start_aa": "Glu", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 223, "end_pos": 225 }, { "start_pos": 509, "end_pos": 511 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVN7-1", "uniprot_ac": "A0A8N7UVN7", "uniprot_id": "A0A8N7UVN7_DANRE", "mass": { "chemical_mass": 49763.0, "monoisotopic_mass": 49763.0 }, "refseq": { "ac": "XP_685746", "name": "photoreceptor ankyrin repeat protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685746" }, "gene_names": [ { "name": "ankrd33aa", "type": "recommended", "evidence": [ { "id": "A0A8N7UVN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVN7" } ] }, { "name": "ankrd33aa", "type": "synonym", "evidence": [ { "id": "XP_685746", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685746" } ] } ], "protein_names": [ { "name": "Photoreceptor ankyrin repeat protein", "type": "synonym", "evidence": [ { "id": "A0A8N7UVN7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVN7/entry#names_and_taxonomy" } ] }, { "name": "photoreceptor ankyrin repeat protein", "type": "synonym", "evidence": [ { "id": "XP_685746", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685746" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_685746.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_685746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685746" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVN7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVN7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ankrd33aa", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVN7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080520-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080520-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVN7", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UVN7", "database": "AlphaFoldDB", "categories": [] }, { "id": "557568", "url": "https://www.ncbi.nlm.nih.gov/gene/557568", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:557568", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557568", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UVN7", "url": "https://www.orthodb.org/?gene=A0A8N7UVN7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24173:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24173:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_685746", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685746", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVN7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVN7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVN7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080520-2", "url": "https://zfin.org/ZDB-GENE-080520-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAGVKVAVQEDPDLGSGPDEDASELSVSENDSDSGSVLSDDSVLPNYEREDASGGPANTLYQACAKNNAAALRRVLERGVTVDEVMELDINGRNGLMLAVSKGFVDIVYGLNQCPFLDINHQDNDGNTALMIAAQAGFVTILTYIINFFPGLDMELRDNRGFTALLKAVMQGSNDCVASLLMAGANLHVVDATRGKDIREWALKTGRFETLHRLRRLNSRPQAEQFCEKYILEWPDLKELVAKATATKSTGQKVAHRLKSTFTFNFPHDPQDNGIMDHMVRMTTSIHSPLVVTGCRPLCPSSPPEVGKRRLAVPELMEMHSGKKLEEHTIRHSNGSISVASTSGSSVSLASCCSESERRGSVLSMASNGVRRFVPRSMARRNSVFPAGCVPQIKVTKSGEPTPKKEKKSKRNKGYLEPPIWKYKEAKEEKKKEKKKEEQEKLEKGAKKKSKK", "length": 452, "header": "tr|A0A8N7UVN7-1|A0A8N7UVN7_DANRE Isoform 1 of Photoreceptor ankyrin repeat protein OS=Danio rerio OX=7955 GN=ankrd33aa PE=4 SV=1 CANONICAL=A0A8N7UVN7-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVN7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVN7/entry#A0A8N7UVN7-1", "sequence": { "sequence": "MAGVKVAVQEDPDLGSGPDEDASELSVSENDSDSGSVLSDDSVLPNYEREDASGGPANTLYQACAKNNAAALRRVLERGVTVDEVMELDINGRNGLMLAVSKGFVDIVYGLNQCPFLDINHQDNDGNTALMIAAQAGFVTILTYIINFFPGLDMELRDNRGFTALLKAVMQGSNDCVASLLMAGANLHVVDATRGKDIREWALKTGRFETLHRLRRLNSRPQAEQFCEKYILEWPDLKELVAKATATKSTGQKVAHRLKSTFTFNFPHDPQDNGIMDHMVRMTTSIHSPLVVTGCRPLCPSSPPEVGKRRLAVPELMEMHSGKKLEEHTIRHSNGSISVASTSGSSVSLASCCSESERRGSVLSMASNGVRRFVPRSMARRNSVFPAGCVPQIKVTKSGEPTPKKEKKSKRNKGYLEPPIWKYKEAKEEKKKEKKKEEQEKLEKGAKKKSKK", "length": 452, "header": "tr|A0A8N7UVN7-1|A0A8N7UVN7_DANRE Isoform 1 of Photoreceptor ankyrin repeat protein OS=Danio rerio OX=7955 GN=ankrd33aa PE=4 SV=1 CANONICAL=A0A8N7UVN7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:557568", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557568", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7URE1-1", "protein_name": "Photoreceptor ankyrin repeat protein", "gene_name": "ankrd33ab", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAVQSSGFEDPHLGSCPDGDEISLLDEDTDSGSLLSEDSVLPEYELEDGKKGTANTLYEACVQNDPEALKRILERGVTCDEVMEVDINGWNGLMVAAYKGFLQIVYELHGCPHLNINHQDNDGNTALMIAAQAGHVSICNYIMNYFPGADTEIRDNRGFTALIKAAIQGRNDVVAALIMHGADVNAVDSNRGKCARDWALKTGRFDTLKRLRHLALHPTAEQFCDTYVPEWPNLKVLVSKATANRSAGQKLTHHLKNRFGFSFPRDPVENGVMDHMVRMTTSLHSPLIATATRPLCPSSPPQMGKRRLAVAELMQKHSEKLLEESSLCHRNSSISSVSPSFHSAEFVSMTCCPDTERRGSVLSIGMRTFIPRSVASRRNSIFPSGCIPQIKVTKSSEPTPKKEKKNKKDKGYLEPPKWKYKEAKEEKKKEKKALKEKEKEEKDKEKKSKDKEKRKKNKYTD", "length": 462 }, "evidence": [ { "id": "MGI:2443398", "url": "https://alliancegenome.org/gene/MGI:2443398#orthology", "database": "AGR" }, { "id": "HGNC:13788", "url": "https://alliancegenome.org/gene/HGNC:13788#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0R7C6-1", "protein_name": "Ankyrin repeat domain 33", "gene_name": "Ankrd33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTEAPPCPGGKTPSPGCGLKTLYWACVHNDLAELQARLDVGVSPDEASQVDGNGRTGLMVACYHGYGSIVALLSGCPFLDVNQQDKDGNTALMLAAQAGHVPLVTLLLNYFAGLDLERRDQRGLTALMKAAIRDRSECVVALLMAGADLSSVDPVRGKTALEWAVLTDSFDTVRKIRQLLRRPQAEQLSLHYQPEWPALAQLVAQAQDQAAPSLLERLQATLNLSFAQFPQEGGVLDHLVTVTTSLASPFLTTACHTLCPDHPPTLGIRGKSVPELLGTAPPPPPAPHPPQEVPVPQAFAPYQSPQSMLSQWLQSRESTSLRSQVPKILLSKAPSPAAQYELILRPPGKQSLTLPIWRFQEKKKKEEEEPRGGRLGQAGGK", "length": 381 }, "evidence": [ { "id": "RGD:1586880", "url": "https://alliancegenome.org/gene/RGD:1586880#orthology", "database": "AGR" }, { "id": "MGI:2443398", "url": "https://alliancegenome.org/gene/MGI:2443398#orthology", "database": "AGR" }, { "id": "HGNC:13788", "url": "https://alliancegenome.org/gene/HGNC:13788#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080520-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080520-2#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z3H0-2", "protein_name": "Photoreceptor ankyrin repeat protein", "gene_name": "ANKRD33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVQPSVTCVASWGGIVHLEAFGDPVIVLRGAWAVPRVDCLIDTLRTPNASCMRKGTHLLVPCLEEEELALHRRRLDMSEALPCPGKETPTPGCRLGALYWACVHNDPTQLQAILDGGVSPEEATQVDSNGRTGLMVACYHGFQSVVALLSHCPFLDVNQQDKGGDTALMLAAQAGHVPLVSLLLNYYVGLDLERRDQRGLTALMKAAMRNRCADLTAVDPVRGKTALEWAVLTDSFDTVWRIRQLLRRPQVEQLSQHYKPEWPALSGLVAQAQAQAQVAPSLLERLQATLSLPFAPSPQEGGVLDHLVTATTSLASPFVTTACHTLCPDHPPSLGTRSKSVPELLGTAPPPPLVPQSPPGSPQRSPWVFVPYQSPQGILSKCLQWLQPRDSTSPRPQVPKILLSKASSSSHQCQPKPSPSGHQSLALPLWRYQELRIEKRKQEEEARMAQK", "length": 452 }, "evidence": [ { "id": "RGD:1586880", "url": "https://alliancegenome.org/gene/RGD:1586880#orthology", "database": "AGR" }, { "id": "MGI:2443398", "url": "https://alliancegenome.org/gene/MGI:2443398#orthology", "database": "AGR" }, { "id": "HGNC:13788", "url": "https://alliancegenome.org/gene/HGNC:13788#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080520-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080520-2#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BXP5-1", "protein_name": "Photoreceptor ankyrin repeat protein", "gene_name": "Ankrd33", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEALPFPSNKTSTPECNLKTLYWACVHNDLAELQARLDAGVSPEEASQVDSNGRTGLMVACYHGFGSIVALLSCCPFLDVNQQDKDGNTALMLAAQAGHMSLVTLLLNYFAGLDLERRDQRGLTALMKAAIQDRSECVVALLMAGADLSSVDPVRGKTALEWAVLTDSFDTAQKIRQLLRRPQAEQLSLHYQPEWPALAQLVAQAQAQAQAPAAPSLLERLQATLSLSFAQSPQEGGVLDHLVTVTTSLASPFLSTACHTLCPDHPPKLGTRGKSVPELLGTAPPPPPEPHPPQQVPVPQVFAPNQSPQSMFSQWLQSRDSTRSQVPKILLSKAPSPSARYELTLRPQGQQSLAPPVWRFQERKKKEEETEPRGGGLGQAGGSK", "length": 385 }, "evidence": [ { "id": "RGD:1586880", "url": "https://alliancegenome.org/gene/RGD:1586880#orthology", "database": "AGR" }, { "id": "MGI:2443398", "url": "https://alliancegenome.org/gene/MGI:2443398#orthology", "database": "AGR" }, { "id": "HGNC:13788", "url": "https://alliancegenome.org/gene/HGNC:13788#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080520-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080520-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "camera-type eye development", "id": "GO:0043010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043010", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVN7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVN7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 30, "end_pos": 32, "annotation": "n_glycosylation_sequon" }, { "start_pos": 334, "end_pos": 336, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 30, "end_pos": 32 }, { "start_pos": 334, "end_pos": 336 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVR0-1", "uniprot_ac": "A0A8N7UVR0", "uniprot_id": "A0A8N7UVR0_DANRE", "mass": { "chemical_mass": 115825.0, "monoisotopic_mass": 115825.0 }, "refseq": { "ac": "XP_686927", "name": "leucine zipper protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686927" }, "gene_names": [ { "name": "luzp1", "type": "recommended", "evidence": [ { "id": "A0A8N7UVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR0" } ] }, { "name": "luzp1", "type": "synonym", "evidence": [ { "id": "XP_686927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686927" } ] } ], "protein_names": [ { "name": "Leucine zipper protein 1", "type": "synonym", "evidence": [ { "id": "A0A8N7UVR0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR0/entry#names_and_taxonomy" } ] }, { "name": "leucine zipper protein 1", "type": "synonym", "evidence": [ { "id": "XP_686927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686927" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_686927.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_686927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686927" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "luzp1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060810-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-90", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "558606", "url": "https://www.ncbi.nlm.nih.gov/gene/558606", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR050719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NVKKIMG", "url": "https://omabrowser.org/oma/group/NVKKIMG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVR0", "url": "https://www.orthodb.org/?gene=A0A8N7UVR0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23166:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23166:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_686927", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686927", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060810-90", "url": "https://zfin.org/ZDB-GENE-060810-90", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTDTTNRHLRHKLQSLGRRLDELEEAKGKLQKAEDELLDIQDKIIQAEGSNSSLLTDVETMRKRLLKIEGKDEEVRKAEDLCREVREKLDQEEKLTKDFKVDIERLQRRMTELEKLEEAFGKSKSDCTQLCLSLNEEKNLTKKLAAELDALKARVKEVDASEGRLDKAEKSLTAEMEKLKSLTQTFMNERKRLLDKQREDDKIILRLTEKLERQKNKVGTTDHSRTDSRDLRIEDELSSGLTCKLARKKSLDYLKHSDDFDLRNESENEKNCLQGQEDNKVKDLSQEVERLKNRLKQMELVEEDLRNMESKNTELIEKYQQERNRSQALHDQVEQMRMELNVCSTSNGNSAITSTTKVLENGKAENEEFNVRGGFRQDKPKFLNRSPASSEQVTSKYKSRDSSPQQRRETKLRNKDLCHSRESSPKTVRRTLGPAHNVRKGQKTGASNTSDNGTRDGKKEEKNASASSCALSESKKVSVLSRYPPAVNDQRSWRPSVKQNDNDGKKSRVEKLSKCPGSDNESSNSDGTHFNSARATIVASPEKGLTEPESLDQDTSAVLSLSKANGSYTAYRSHVSPSFLTDHGSDGHSSASETESTGSRRSVGEQSDPLVSSTSGRTSKYTRYSRLQDSYSDASSKSPFSEEQQRPLTMEEEAQETAHSSSGIEVRRVCSPRESLQSKAVIKQAIVEIDRKEVMSGGTTEALTTSGKPKISTKPVLTSKMTSSITFYPNDPSSSRTSSRSSSLSSEPPSKERHTSTSNIVIGPSSEHRGSISIPYEISIPKSELTLRQSETDTDFSEPHSYLETAPLEATLLSQNSFSLQSSDASDFNNDIESGFESSSSSTTVTSWRSHAHNHLSYDDSLPEMRNITVRSTWKSRGAASVDESVRALRQDGSEDESESSTTWRAYRATTVLDTPANSSIGANCANKPSPAEVYMRRINNSASSVPEPGRRNKKTPSPERAIAHEPVSAQQLQPRVRKQPLSVDDRDPALSSWRRQPAGDLDPYDRPGSRGAWSSRNRTADGSRSWSNRHLDN", "length": 1034, "header": "tr|A0A8N7UVR0-1|A0A8N7UVR0_DANRE Isoform 1 of Leucine zipper protein 1 OS=Danio rerio OX=7955 GN=luzp1 PE=4 SV=1 CANONICAL=A0A8N7UVR0-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVR0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR0/entry#A0A8N7UVR0-1", "sequence": { "sequence": "MTDTTNRHLRHKLQSLGRRLDELEEAKGKLQKAEDELLDIQDKIIQAEGSNSSLLTDVETMRKRLLKIEGKDEEVRKAEDLCREVREKLDQEEKLTKDFKVDIERLQRRMTELEKLEEAFGKSKSDCTQLCLSLNEEKNLTKKLAAELDALKARVKEVDASEGRLDKAEKSLTAEMEKLKSLTQTFMNERKRLLDKQREDDKIILRLTEKLERQKNKVGTTDHSRTDSRDLRIEDELSSGLTCKLARKKSLDYLKHSDDFDLRNESENEKNCLQGQEDNKVKDLSQEVERLKNRLKQMELVEEDLRNMESKNTELIEKYQQERNRSQALHDQVEQMRMELNVCSTSNGNSAITSTTKVLENGKAENEEFNVRGGFRQDKPKFLNRSPASSEQVTSKYKSRDSSPQQRRETKLRNKDLCHSRESSPKTVRRTLGPAHNVRKGQKTGASNTSDNGTRDGKKEEKNASASSCALSESKKVSVLSRYPPAVNDQRSWRPSVKQNDNDGKKSRVEKLSKCPGSDNESSNSDGTHFNSARATIVASPEKGLTEPESLDQDTSAVLSLSKANGSYTAYRSHVSPSFLTDHGSDGHSSASETESTGSRRSVGEQSDPLVSSTSGRTSKYTRYSRLQDSYSDASSKSPFSEEQQRPLTMEEEAQETAHSSSGIEVRRVCSPRESLQSKAVIKQAIVEIDRKEVMSGGTTEALTTSGKPKISTKPVLTSKMTSSITFYPNDPSSSRTSSRSSSLSSEPPSKERHTSTSNIVIGPSSEHRGSISIPYEISIPKSELTLRQSETDTDFSEPHSYLETAPLEATLLSQNSFSLQSSDASDFNNDIESGFESSSSSTTVTSWRSHAHNHLSYDDSLPEMRNITVRSTWKSRGAASVDESVRALRQDGSEDESESSTTWRAYRATTVLDTPANSSIGANCANKPSPAEVYMRRINNSASSVPEPGRRNKKTPSPERAIAHEPVSAQQLQPRVRKQPLSVDDRDPALSSWRRQPAGDLDPYDRPGSRGAWSSRNRTADGSRSWSNRHLDN", "length": 1034, "header": "tr|A0A8N7UVR0-1|A0A8N7UVR0_DANRE Isoform 1 of Leucine zipper protein 1 OS=Danio rerio OX=7955 GN=luzp1 PE=4 SV=1 CANONICAL=A0A8N7UVR0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7I8J7-1", "protein_name": "Leucine zipper protein 1 isoform X1", "gene_name": "Luzp1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADMASYKDAASSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQEKVIQAEGSNSSMLAEIEVLRQRVLKIEGKDEEIKRAEDLCHTMKEKLEEEENLTRELKSEIEWLQKRMADLEKLEEALSRSKNECSQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLVSELEKLKSLTLSFVNERKYLNEKEKENEKLIKELTQKLEQNKKMSRDHTRNASTLLERNDLRIEDGISSTLPSKELRRKGSLDYLKQVENETRDKSENEKNQNQEDNKVKDLNQEIQKLKTQIKHFESLEEELKKMRAKNNDLQDNYLTELNKNKILASQLEEIKLQVKKQKELGNGDIEGEDAFLLGRGRHERTKLRGHGGEASVSRHIPRELSPQHKRERIRNREFALNNENYSLSNKQASSIFTNRRAAKASNMGVGADNGSQETKRAEDRFLPGSSQSEGKKCREQPSVLSRYPPAAQEHNKVWKGTLKPGTESGLKGKVEKTTRTFSDSTHGPVPNDTMGRGDKTSEISEAHYGKRGQVPGNGSQVTQAAESGCSKATGALSSSQRASSEGISKSKRAANGLEADANFPNSKAPILSKYPYSSRSQENIPQGFSVPNKEGLDQSVAVVMEDSSQHEALRCRVIKSSGKEKPDSDDDLDIESLVTAKLVNTTITPEPEPKQQPNSREKVKSRGPRTALFENDKNAATENESMKSTRASSSAVEFPDANGVGAKNQRLFSPREALRSRAIIKPVIIDKDVKKIMGGSGTEVVLEKQRSTSNPVPSKVTSSITIYPSESSGPRAVQGEAPRERHTSTSNIQVGHPELTSVSNHVNSPLELSIHKHDITLQLTEAERMGDGSPKNRPETVVSRSSILIKPSDSVERNSHAPQAETVRWKSHNASSEVGSSDTRHVTVRNAWKSKRDFKCSEDVPTRVGRHMESTNAYTQRSSTDFLELEQPRSLPSEQGTRKVGDAGDAPELSSRRTQSSLTASEVITRRNRIGDAITATTWNHSASLEEGEDGTSVTSRRMHNTLEHSELPGKQGLPEPGIWAEERLQPARPYAEED", "length": 1069 }, "evidence": [ { "id": "A0A8N7UVR0", "url": "https://omabrowser.org/oma/group/A0A8N7UVR0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0YPS1-1", "protein_name": "Leucine zipper protein 1", "gene_name": "LUZP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEFTGYKETSNRHLRFKLQSLSRRLDELEEATKNLQKAEDELLELQDKVIQAEGSNSSMLADIEALRKRVLKIEGKDEEIKKAEELCRLMKEKLEEEESLTRELKSEIEHLQKRMAELEKLEEAFGRSKNDCTQLCLSLNEERNLTKKISTELEILRVKVKELEASEERMDKTEQSLTGELEKLKSLALSFISERKHFNEREKQNEKIIQELTLKLEQNNKLNRADQTRNASNLLERSSNNLLDRNDLRIEDDLTSALPSKETRRKGSVDYLKHVENETRNKSENQKNKNQEDNKVKDLTQEIERLKTQIKRFESLEEELKKMRAKNNDLQDSYLSEQNKNKLLTGELEEIKMQIKKQKDLENGEVENEDTSFSGRGKHDRAKYRVVAADFTAAKHKPREVSPQQRRERVRNRDFSFSNDSSSHGGKQTPSPSLMSRKAGKTSGAAALADAAATDTKKLEEKCLVSTFSSGQKEASFTQNEGKRPKEQPSVLSRYPPAAHEQKSWKTPSKPVSDLRSKAEKPSQATRGSCQSGADTRDEKSSRGESVASLAEKLKTNQGEVSDAVGDTQQSRGHCASANGVATAYRCHISPAESDPVGSKAEAGNASTASHRQPLEGRTKRAVISQEKELIDVSLESVKASPLTKRSHRSRSQEDILQILKEDAEQSAAAGHVNASLKAGSKTVQSSHEKLNSDEEAGRSKKANTQSDFETRKKANSKQFSNSRGVFRASLFENDKSTAHDEDSSKCIKPSDADTGGLKSRRSFSPREALRSKAIIKPAIVEKDMKAIMGGAVTETESEKQKSVIKAVTNKMTSSITIFPSEPTVPRPSTDTAGKERHITTSNIRVAPNEPSPITNSLPQPFEVSVNRSALKLSETDRSGDAVLRSRTETVVSRSSIVIKTSEPPERSGELPLDTASSRSHGSPDSISSETKHVTLRSSWRTRQGLPSLEDSQIKVEKNAASSPTNACRSSVDLSEMEGSSTRTNSLEQSSARSGATTNSWSAPEMGSRRTKSNLSASELLTRRSYTSDPTTASPWHRTTLPDESKDFVSSSRRKQYGSSEYLSQADTAGRRAVPPPEQLQDPTSNPNSPPGLQAEDQGASRVGRPTSRR", "length": 1111 }, "evidence": [ { "id": "A0A8N7UVR0", "url": "https://omabrowser.org/oma/group/A0A8N7UVR0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9S794-1", "protein_name": "Leucine zipper protein 1", "gene_name": "LUZP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAEFTSYKDTASSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAEVEVLRQRVLRIEGKDEEIKKAEDLCQLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRIKVKELESSEDRLDKTEQSLVSELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLLERNDLRIEDGISSPLPSKESRRKGALDYLKLAENETRNKSENEKNRNQEDNKVKDLTQEIEKLKTQIKHFESLEEELKKMRAKNNDLQDNYLSEQNKNKLLASQLEEIKLQIKKQKELENGEVEGEDAFLSGRGRHERTKLRGHGSEASAKHMARELSPQHKRERHCNRELTLNNENPLKNRQVSSPSFTNRKTAKASHAGAGADSGAQETRRTEDRFTAGSSQSEGKKSREQPPVLSRYPPAAQEHSKVWKGAPKPGTESGLKGKVEKATRTFSDNTHGSVSNDVSGRGDKASETSTEAPFGKRGQVPGSGSQITQAADAGSSKAVGALATSRRSSSEGLSKGKKATSGLEADTSFPSSKTPPLSKYPYSSRSQENILQGFSTPSKEGVEQPVAVVMEDSSQHEALRCRVTKSSGREKPDSDDDMDMVSLVTAKLVNTTITPEPEPPHQPQSREKAKSRGAVRASLFENDKDIGTENESGKAVRASANAMELPEANGSGAKSQRPFSPREALRSRAIIKPVIIDKDVKKIMGGSGTEAALEKQKSASKPGPNKVTSSITIYPSDSGSPRAAPGEAARERHTSTSNIQVGLPELASVSNHVSSPFELSIHKHDITLQLSEAERTGDGSLKNRPETVVSRSSIIIKPSDPVERNSHAPTVETIRWKSHSAPLEAGSPDARHITVRNAWKSRRDLNSSEDSPARVGRHVESPNPHTQRSSSDCSDPEQPGSYLSEQGTRRGGTSGEVPELASRRTQSSLAVSEVFTRRSRAGDAVPAEAWNHLAGTVGPASPPCPLLLPPSPFPSVLSSWFSSAPACVTRDAGDFGVRKH", "length": 1064 }, "evidence": [ { "id": "A0A8N7UVR0", "url": "https://omabrowser.org/oma/group/A0A8N7UVR0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LNF8-1", "protein_name": "Leucine zipper protein 1", "gene_name": "LUZP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAEFTSYKDTASSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAEIEVLRQRVLRIEGKDEEIKRAEDLCQLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLVSELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLLERNDLRIEDGISSLPSKESRRKGTLDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMRAKNNDLQDNYVREQNKNKLLASQLEEIKLQIKKQKELENGEVEGEDALLSSKGRHERTKFRGHANEASVSKHTPRELSPQHKRERHRNREFAINNENYSLSNRQVSSPSFTSRRTAKASNTGAGVDSGTQETKRTEDRFTSGSSQSEGKKSREQPSVLSRYPPAAQEHSKVWKGTPRPGTEGGLKGKVEKTTRTFSDTSHGSVPNDISGRGDKTSDASAEALLSKRGQVPGNGSQITQAADSGSSKAIGALATSRRSSSEGLSKGKKAANGPESDTNSPNSKAPPLSKYSYSSRSQENILQGFSTPNKEGVDQPVAVVMEDSSQHEALRCRVIKSSGREKPDSDDDMDTVSLVTAKLVNTTITPEPEPKQQPNSREKAKSRGGLRPSLFENDKDVGTENESGKPVRASTNAMELPEANGAGVKNQRPFSPREALRSKAIIKPVIIDKDVKKIMGGSGTEATLEKQKPTSRPGPNKVTSSITIYPSDSSSPRAAPGEALRERHTSTSNIQVGPPDLTALSNHISSPFELSIHKHDFTLQFTEAERPGEGPLKNKPETVVSRSSIIIKPSEPVERNSHAPAAETIRWKSHSAPLEVGSSDARHVTVRNAWKSRRDLNSFEDPPTRIGKNVESTNAYTQRSSTDYSDLEQPGSYLSEQGTRRVGNSGDAPELSSRRTQSSLTVSEVLTRRNRVGDAVTAPAWNHSAGTEEGDDCTLGVYRRLHNSLERSELSAKQGLPEPGRARGEERLRPSRPCAEEN", "length": 1072 }, "evidence": [ { "id": "A0A8N7UVR0", "url": "https://omabrowser.org/oma/group/A0A8N7UVR0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q86V48-1", "protein_name": "Leucine zipper protein 1", "gene_name": "LUZP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEFTSYKETASSRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAEIEVLRQRVLRIEGKDEEIKRAEDLCRLMKEKLEEEENLTRELKSEIERLQKRMAELEKLEEAFSRSKNDCTQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLASELEKLKSLTLSFVSERKYLNEKEKENEKLIKELTQKLEQNKKMNRDYTRNASNLERNDLRIEDGISSTLPSKESRRKGGLDYLKQVENETRNKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMKSKNNDLQDNYLSEQNKNKLLASQLEEIKLQIKKQKELENGEVEGEDAFLSSKGRHERTKFRGHGSEASVSKHTARELSPQHKRERLRNREFALNNENYSLSNRQVSSPSFTNRRAAKASHMGVSTDSGTQETKKTEDRFVPGSSQSEGKKSREQPSVLSRYPPAAQEHSKAWKGTSKPGTESGLKGKVEKTTRTFSDTTHGSVPSDPLGRADKASDTSSETVFGKRGHVLGNGSQVTQAANSGCSKAIGALASSRRSSSEGLSKGKKAANGLEADNSCPNSKAPVLSKYPYSCRSQENILQGFSTSHKEGVNQPAAVVMEDSSPHEALRCRVIKSSGREKPDSDDDLDIASLVTAKLVNTTITPEPEPKPQPNSREKAKTRGAPRTSLFENDKDAGMENESVKSVRASTNTMELPDTNGAGVKSQRPFSPREALRSRAIIKPVIVDKDVKKIMGGSGTETTLEKQKPVSKPGPNKVTSSITIYPSDSSSPRAAPGEALRERHTSTSNIQVGLAELTSVSNHVSSPFELSIHKHDITLQLAEAERMADGPLKDRPETVVSRSSIIIKPSDPVERNSHAPPAETIRWKSHSAPSEVGFSDARHVTVRNAWKSRRDLKSLEDPPTRIGKNVESTNSNAYTQRSSTDFSELEQPRSCLFEQGTRRVGPSSGDAPEPSSRRTQSSLTVSEVLTRRNRVGDTITVAAWNHSASMEEEGEDCTLSVYRQLHNSLDPSELPGKQGLPESGRVRAEERLRPTRPCAEEN", "length": 1076 }, "evidence": [ { "id": "HGNC:14985", "url": "https://alliancegenome.org/gene/HGNC:14985#orthology", "database": "AGR" }, { "id": "RGD:61839", "url": "https://alliancegenome.org/gene/RGD:61839#orthology", "database": "AGR" }, { "id": "MGI:107629", "url": "https://alliancegenome.org/gene/MGI:107629#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060810-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-90#orthology", "database": "AGR" }, { "id": "A0A8N7UVR0", "url": "https://omabrowser.org/oma/group/A0A8N7UVR0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R4U7-1", "protein_name": "Leucine zipper protein 1", "gene_name": "Luzp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAELTNYKDAASNRHLRFKLQSLSRRLDELEEATKNLQRAEDELLDLQDKVIQAEGSDSSTLAEIEVLRQRVLKIEGKDEEIKRAEDLCHTMKEKLEEEENLTRELKSEIERLQKRMVDLEKLEEALSRSKNECSQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLDKTEQSLVSELEKLKSLTLSFVNERKYLNEKEKENEKIIKELTQKLEQNKKMNRDHMRNASTFLERNDLRIEDGISSTLSSKESKRKGSLDYLKQVENETRDKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMRAKNNDLQDNYLTELNRNRSLASQLEEIKLQVRKQKELGNGDIEGEDAFLLGRGRHERTKLKGHGSEASVSKHTSRELSPQHKRERLRNREFALSNEHYSLSSKQASSPVFTNKRAAKASNMGMGTDSGTQETKRTEDRFAPGSSHSEGKRGREQPSVLSRYPPAAQEHTKVWKGAPKPGTESGLKGKVEKTTRTFSDSTHVSVPNDIVGKGDKTSDLSSEAHCGKRGQVPGHASQGTQAVESSCSKAIGALSSSQKASSEGLSKGKKTANGLAADANFSNSKAPILSKYPYSSRSQENILQGFSLPNKEGVDQPVAVVMEDSSQHEALRCRVIKSSGREKPDSDDDLDIESFVTAKLVNTTITPEPEPKPQPNSREKVKSRGGTRTALFENDKNAAIENDSVKPTRPSSNAIEFPDANCAGVKNQRPFSPREALRSRAIIKPVIIDKDVKKIMGGSGTEVVLEKQKSTSKSVTSKVTSSITIYPSDSSGPRAVPSEAPRERHTSTSNIQVGPPELTAISNHVSSPLELSIHKHDITLQLTEAERVGDGSPKNRAEMVVSRSSILIKPSESVEKNSHVPPAETIRWKSHSASSDSRHITVRNAWKSKRDLKCSEDPPTGIGRNMEATNAYTQRPCTDFLELEQPRSQPSEQGARRVGNSGDAPELSPRRTQSSLTASEVLTRRDRMGGAITAASCNHSSSMEEGEDSTFVTSRRIHNPLEHSELPGKQGLPEPEPVWTEERLHPAKPYAEED", "length": 1068 }, "evidence": [ { "id": "HGNC:14985", "url": "https://alliancegenome.org/gene/HGNC:14985#orthology", "database": "AGR" }, { "id": "RGD:61839", "url": "https://alliancegenome.org/gene/RGD:61839#orthology", "database": "AGR" }, { "id": "MGI:107629", "url": "https://alliancegenome.org/gene/MGI:107629#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060810-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-90#orthology", "database": "AGR" }, { "id": "A0A8N7UVR0", "url": "https://omabrowser.org/oma/group/A0A8N7UVR0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ESV1-1", "protein_name": "Leucine zipper protein 1", "gene_name": "Luzp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADIANYKDAASNRHLRFKLQSLSRRLDELEEATKNLQKAEDELLDLQDKVIQAEGSNSSMLAEIEVLRQRVLKIEGKDEEIKRAEDLCHTMKEKLEEEENLTRELKSEIDRLQKRMADLEKLEEALSRSKNECSQLCLSLNEERNLTKKISSELEMLRVKVKELESSEDRLEKTEQSLVSELEKLKSLTLSFVNERKYLNEKEKENEKLIKELTQKLEQNKKINRDHMRNASTFLERNDLRIEDGISSTLPSKESRRKGSLDYLKQVENETRDKSENEKNRNQEDNKVKDLNQEIEKLKTQIKHFESLEEELKKMRAKNNDLQDNYLTELNKNRSLASQLEEVKLQVKKQKELGNGDIEGEDAFLLGRGRHERTKLKGHGGEVSVSKHTSREQSPQHKRERLRNRGFALNDEHCSLSNKQVSSPAFTNKRAAKASNMGVGPDSGTQETKRTEDRLAPGSSQSEGKKGREQPSVLSRYPPAAQDHTKVWRGNPKPGTESGLKGKVEKTTRTFSDSAHGSVPNDVVGKGDKTSDFSSEAHCGKRGQVPGHASQVTQVAESGCSKAIGALASSQRASSEGLSKGKKAANGLETDANFPHSKAPILSKYPYSSRSQENILQGFSVPNKEGVDHSVAVVMEDSSQHEALRCRVIKSSGREKPDSDDDLDIESLVTAKLVNTTITPEPEPKLQPNSREKVKSRGGTRTPLFENDKNAAVENDSAKSMRSSSNAVEFPDANCAGVKNQRPFSPREALRSRAIIKPVIIDKDVKKIMGGSGTEVVLEKQKSTPKSVTSKVTSSITIYPSDSSGPRAVPTEAPRERHTSTSNIQVGPPELTSVSNHISSPLELSIHKHDITLQLTEAERVGDGSPKNRAETVVSRSSILIKPSDSVERNSHAFPAETIRWKSHSTSSEVASSDTRHITVRNAWKSKRDLKCSEDPPTRIGRNVEATNAYTQRSSTDFLELEQPRSHPPEQGTRKVGNSGDAPELSSRRTQSSLTASEVLTRRNRIGDAVTAASWNHSSNVVSLTFLPSALICLTEDLGNTEGWEMLNLR", "length": 1051 }, "evidence": [ { "id": "HGNC:14985", "url": "https://alliancegenome.org/gene/HGNC:14985#orthology", "database": "AGR" }, { "id": "RGD:61839", "url": "https://alliancegenome.org/gene/RGD:61839#orthology", "database": "AGR" }, { "id": "MGI:107629", "url": "https://alliancegenome.org/gene/MGI:107629#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060810-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-90#orthology", "database": "AGR" }, { "id": "A0A8N7UVR0", "url": "https://omabrowser.org/oma/group/A0A8N7UVR0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein localization to actin cytoskeleton", "id": "GO:1903119", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903119", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR0" } ], "pmid": "" }, { "name": "actin cytoskeleton", "id": "GO:0015629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015629", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVR0", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1018, "end_pos": 1020, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 384, "end_pos": 386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 448, "end_pos": 450, "annotation": "n_glycosylation_sequon" }, { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 463, "end_pos": 465, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" }, { "start_pos": 520, "end_pos": 522, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 867, "end_pos": 869, "annotation": "n_glycosylation_sequon" }, { "start_pos": 918, "end_pos": 920, "annotation": "n_glycosylation_sequon" }, { "start_pos": 940, "end_pos": 942, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1018, "end_pos": 1020 }, { "start_pos": 139, "end_pos": 141 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 384, "end_pos": 386 }, { "start_pos": 448, "end_pos": 450 }, { "start_pos": 452, "end_pos": 454 }, { "start_pos": 463, "end_pos": 465 }, { "start_pos": 51, "end_pos": 53 }, { "start_pos": 520, "end_pos": 522 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 867, "end_pos": 869 }, { "start_pos": 918, "end_pos": 920 }, { "start_pos": 940, "end_pos": 942 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVR9-1", "uniprot_ac": "A0A8N7UVR9", "uniprot_id": "A0A8N7UVR9_DANRE", "mass": { "chemical_mass": 126282.0, "monoisotopic_mass": 126282.0 }, "refseq": { "ac": "XP_687737", "name": "zinc finger CCCH domain-containing protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687737" }, "gene_names": [ { "name": "zc3h6", "type": "recommended", "evidence": [ { "id": "A0A8N7UVR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR9" } ] }, { "name": "zc3h6", "type": "synonym", "evidence": [ { "id": "XP_687737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687737" } ] } ], "protein_names": [ { "name": "Zinc finger CCCH domain-containing protein 6", "type": "synonym", "evidence": [ { "id": "A0A8N7UVR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR9/entry#names_and_taxonomy" } ] }, { "name": "zinc finger CCCH domain-containing protein 6", "type": "synonym", "evidence": [ { "id": "XP_687737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687737" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_687737.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_687737", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687737" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVR9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zc3h6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120727-18", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120727-18", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVR9", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UVR9", "database": "AlphaFoldDB", "categories": [] }, { "id": "559312", "url": "https://www.ncbi.nlm.nih.gov/gene/559312", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036855", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036855", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:559312", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559312", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UVR9", "url": "https://www.orthodb.org/?gene=A0A8N7UVR9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13119", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13119", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13119:SF22", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13119:SF22", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14608", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14608", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22623", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22623", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_687737", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687737", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVR9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120727-18", "url": "https://zfin.org/ZDB-GENE-120727-18", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": 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"length": 1134, "header": "tr|A0A8N7UVR9-1|A0A8N7UVR9_DANRE Isoform 1 of Zinc finger CCCH domain-containing protein 6 OS=Danio rerio OX=7955 GN=zc3h6 PE=4 SV=1 CANONICAL=A0A8N7UVR9-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVR9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR9/entry#A0A8N7UVR9-1", "sequence": { "sequence": 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"length": 1134, "header": "tr|A0A8N7UVR9-1|A0A8N7UVR9_DANRE Isoform 1 of Zinc finger CCCH domain-containing protein 6 OS=Danio rerio OX=7955 GN=zc3h6 PE=4 SV=1 CANONICAL=A0A8N7UVR9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1053, "start_aa": "Thr", "end_pos": 1053, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1053", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", 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"orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of DNA-templated transcription, elongation", "id": "GO:0032785", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032785", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVR9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVR9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVR9", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR9" } ], "pmid": "" }, { "name": "DNA-binding transcription repressor activity, RNA 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"interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UVR9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVR9" }, { "id": "PS50103", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50103" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C3H1-type", "eco_id": "ECO_0000259", "start_pos": 304, "end_pos": 326, "start_aa": "Ile", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 429, 655, 1053 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1043, "end_pos": 1045 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 858, "end_pos": 860 }, { "start_pos": 922, "end_pos": 924 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"count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVS5-1", "uniprot_ac": "A0A8N7UVS5", "uniprot_id": "A0A8N7UVS5_DANRE", "mass": { "chemical_mass": 30042.0, "monoisotopic_mass": 30042.0 }, "refseq": { "ac": "XP_706588", "name": "putative uncharacterized protein C8orf89 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706588" }, "gene_names": [ { "name": "si:ch211-171b20.3", "type": "recommended", "evidence": [ { "id": "A0A8N7UVS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVS5" } ] }, { "name": "si:ch211-171b20.3", "type": "synonym", "evidence": [ { "id": "XP_706588", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706588" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "A0A8N7UVS5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVS5/entry#names_and_taxonomy" } ] }, { "name": "putative uncharacterized protein C8orf89 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_706588", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706588" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_706588.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_706588", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706588" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVS5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVS5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-171b20.3", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVS5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-278", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-278", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "571370", "url": "https://www.ncbi.nlm.nih.gov/gene/571370", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040505", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040505", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UVS5", "url": "https://www.orthodb.org/?gene=A0A8N7UVS5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF17690", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17690", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_706588", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706588", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVS5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVS5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVS5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRG5", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRG5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRG9", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IRG9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IRG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-278", "url": "https://zfin.org/ZDB-GENE-091204-278", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKPYASVVRPKLMSLPIEASLMIQDITDARPSSTFSPPVSGYFSTADSRLNVFSGRPTHNSRDLKFHTVSSVKDGPLLPCIANDRAEFTKCTSQNNMPDRNISGRHFLFDKRWRNGTYMKHGIEEDVLNNHNPGALSQEFHVYHSHNLTKFAHRKELFPRDTRPRICDSSRSDYLESFPSILLPVTTPSISGRVCLSQNFKNRTRMKNSLFPIDANKTQSYLDPHLGATASFVQRLSEISSLEVETVRQEKMKRLRKINRQDS", "length": 263, "header": "tr|A0A8N7UVS5-1|A0A8N7UVS5_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=si:ch211-171b20.3 PE=4 SV=1 CANONICAL=A0A8N7UVS5-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVS5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVS5/entry#A0A8N7UVS5-1", "sequence": { "sequence": "MKPYASVVRPKLMSLPIEASLMIQDITDARPSSTFSPPVSGYFSTADSRLNVFSGRPTHNSRDLKFHTVSSVKDGPLLPCIANDRAEFTKCTSQNNMPDRNISGRHFLFDKRWRNGTYMKHGIEEDVLNNHNPGALSQEFHVYHSHNLTKFAHRKELFPRDTRPRICDSSRSDYLESFPSILLPVTTPSISGRVCLSQNFKNRTRMKNSLFPIDANKTQSYLDPHLGATASFVQRLSEISSLEVETVRQEKMKRLRKINRQDS", "length": 263, "header": "tr|A0A8N7UVS5-1|A0A8N7UVS5_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=si:ch211-171b20.3 PE=4 SV=1 CANONICAL=A0A8N7UVS5-1" }, "locus": {} }, { "isoform_ac": "A0AC58IRG5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVS5/entry#A0AC58IRG5-1", "sequence": { "sequence": "MKPYASVVRPKLMSLPIEASLMIQDITDARPSSTFSPPVSGYFSTADSRLNVFSGRPTHNSRDLKFHTVSSVKDGPLLPCIANDRAEFTKCTSQNNMPDRNISGRHFLFDKRWRNGTYMKHGIEEDVLNNHNPGALSQEFHVYHSHNLTKFAHRKELFPRDTRPRICDSSRSDYLESFPSILLPVTTPSISGRVCLSQNFKNRTRMKNSLFPIDANKIVP", "length": 220, "header": "tr|A0AC58IRG5-1|A0AC58IRG5_DANRE Computationally mapped isoform of Uncharacterized protein OS=Danio rerio OX=7955 GN=si:ch211-171b20.3 PE=4 SV=1 CANONICAL=A0A8N7UVS5-1" }, "locus": {} }, { "isoform_ac": "A0AC58IRG9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVS5/entry#A0AC58IRG9-1", "sequence": { "sequence": "MKPYASVVRPKLMSLPIEASLMIQDITDARPSSTFSPPVSGYFSTADSRLNVFSGRPTHNSRDLKFHTVSSVKDGSSRSDYLESFPSILLPVTTPSISGRVCLSQNFKNRTRMKNSLFPIDANKTQSYLDPHLGATASFVQRLSEISSLEVETVRQEKMKRLRKINRQDS", "length": 170, "header": "tr|A0AC58IRG9-1|A0AC58IRG9_DANRE Computationally mapped isoform of Uncharacterized protein OS=Danio rerio OX=7955 GN=si:ch211-171b20.3 PE=4 SV=1 CANONICAL=A0A8N7UVS5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "F6QJK4-1", "protein_name": "RIKEN cDNA 4930444P10 gene", "gene_name": "4930444P10Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSMLSPEIKFETSNATRSNLDNCFLFESSWRKAVLETQKMRKAFGLEEPKECLKMPYLPELSKSSSSSSLEAHKRLLHTDAEIPPIRIKKTKESCSMAAFQEKSKGSVFSDPFTGAPSDFLQRLSRMAILEYDTIRQETHKKLRRGKKRDLRDC", "length": 154 }, "evidence": [ { "id": "HGNC:51258", "url": "https://alliancegenome.org/gene/HGNC:51258#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R8B2-1", "protein_name": "Similar to human chromosome 8 open reading frame 89", "gene_name": "C5h8orf89", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSMLSPEIKFETSNVTRSSMDNCFLFESSWRKAVLETQKMRKAFGLEEPKECLKMPYLPELSKSLSSSPLEAHKRLLHTEAEIPPIRIKKTKESCSMAALQEKSKGSVFSDPFTGAPSDFLQRLSKMAILEYDTVRQETHKKLRRGKKRDLRDC", "length": 154 }, "evidence": [ { "id": "HGNC:51258", "url": "https://alliancegenome.org/gene/HGNC:51258#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P0DMQ9-1", "protein_name": "Putative uncharacterized protein C8orf89", "gene_name": "C8orf89", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVLSPEIKCETSKFTRSSFGSCLIFESSWKKAVLETQKIKKEYTTAFGLEELKECIKMPYLPGLQSCQKSVSSTPLEVPKRLPRADAEVSAVRLKKTKETCSVAPLWEKSKGSGFSDPLTGAPSQYLERLSKIAILEYDTIRQETTTKSKKSKKRDLRDR", "length": 161 }, "evidence": [ { "id": "HGNC:51258", "url": "https://alliancegenome.org/gene/HGNC:51258#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-278", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-278#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 115, "end_pos": 117, "annotation": "n_glycosylation_sequon" }, { "start_pos": 147, "end_pos": 149, "annotation": "n_glycosylation_sequon" }, { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 115, "end_pos": 117 }, { "start_pos": 147, "end_pos": 149 }, { "start_pos": 202, "end_pos": 204 }, { "start_pos": 216, "end_pos": 218 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UVX5-1", "uniprot_ac": "A0A8N7UVX5", "uniprot_id": "A0A8N7UVX5_DANRE", "mass": { "chemical_mass": 46594.0, "monoisotopic_mass": 46594.0 }, "refseq": { "ac": "XP_692994", "name": "stAR-related lipid transfer protein 7, mitochondrial", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692994" }, "gene_names": [ { "name": "stard7", "type": "recommended", "evidence": [ { "id": "A0A8N7UVX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX5" } ] }, { "name": "stard7", "type": "synonym", "evidence": [ { "id": "XP_692994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692994" } ] } ], "protein_names": [ { "name": "StAR-related lipid transfer protein 7, mitochondrial", "type": "recommended", "evidence": [ { "id": "A0A8N7UVX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX5/entry#names_and_taxonomy" } ] }, { "name": "START domain-containing protein 7", "type": "synonym", "evidence": [ { "id": "A0A8N7UVX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX5/entry#names_and_taxonomy" } ] }, { "name": "stAR-related lipid transfer protein 7, mitochondrial", "type": "synonym", "evidence": [ { "id": "XP_692994", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692994" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_692994.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_692994", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692994" } ] }, { "annotation": "May play a protective role in mucosal tissues by preventing exaggerated allergic responses.", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVX5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX5#function" }, { "database": "UniProtKB", "id": "ARBA00053168", "url": "https://www.uniprot.org/uniprotkb/ARBA00053168#function" } ] } ], "disease": [ { "disease_id": "DOID:0111692", "recommended_name": { "id": "DOID:0111692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111692", "name": "familial adult myoclonic epilepsy 2", "description": "A familial adult myoclonic epilepsy characterized by onset of tremor affecting the fingers, hand, and voice in adolescence or young adulthood with somewhat later onset of rhythmic myoclonic jerks and generalized tonic-clonic seizures that has_material_basis_in a heterozygous 5-bp repeat expansion in STARD7 on chromosome 2q11.2." }, "synonyms": [ { "id": "DOID:0111692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111692", "name": "ADCME", "description": "" }, { "id": "DOID:0111692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111692", "name": "BAFME2", "description": "" }, { "id": "DOID:0111692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111692", "name": "FAME2", "description": "" }, { "id": "DOID:0111692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111692", "name": "FCMTE2", "description": "" }, { "id": "DOID:0111692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111692", "name": "autosomal dominant cortical myoclonus and epilepsy", "description": "" }, { "id": "DOID:0111692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111692", "name": "benign adult familial myoclonic epilepsy 2", "description": "" }, { "id": "DOID:0111692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111692", "name": "familial cortical myoclonic tremor and epilepsy 2", "description": "" }, { "id": "MONDO:0011930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011930", "name": "epilepsy, familial adult myoclonic, 2", "description": "Any epilepsy, familial adult myoclonic in which the cause of the disease is a mutation in the ADRA2B gene." }, { "id": "MONDO:0011930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011930", "name": "ADRA2B epilepsy, familial adult myoclonic", "description": "" }, { "id": "MONDO:0011930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011930", "name": "epilepsy, familial adult myoclonic caused by mutation in ADRA2B", "description": "" }, { "id": "MONDO:0011930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011930", "name": "epilepsy, familial adult myoclonic, 2", "description": "" }, { "id": "MONDO:0011930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011930", "name": "epilepsy, familial adult myoclonic, type 2", "description": "" }, { "id": "MONDO:0011930", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011930", "name": "FAME2", "description": "" }, { "id": "MIM:607876", "resource": "MIM", "url": "https://www.omim.org/entry/607876", "name": "Epilepsy, familial adult myoclonic, 2", "description": "Epilepsy, familial adult myoclonic, 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111692", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111692" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19308:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01852", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01852", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_692994", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692994", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UVX5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UVX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-2310", "url": "https://zfin.org/ZDB-GENE-030131-2310", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFPSVQHRPVCSIGARAVRLQSISSFSNSGAKSSKSFRFSWLGERVGLLMSWLQKAGRGTNKLASDNKKEKLLSIFANHCSFVTGQRLRRAFQIGELYSNLYSERTRWTLVGSIWRRLQSKHAPTGKLVAALAGVFMWEDEKIRDDELRRCAWELQAVESVRSQDVSPKVATHVDQGWEVVMEKKNFRVWRRPVEGSHLFEYRVFGSYTDVTPRQFFNVQLDTEYRKKWDALVIRLDVVDRDVNTGTEVVHWATHFPYPMYSRDYVYVRRYQVDLENNLMILVSRAVKHPCVPETQEFVRVHSYQSKMVIRPHRSFDENGFDYLLTYSDDPQTVFPRYCVSWMVSSGMPDFLEKLHTAALRAKNMDVSVHDYVNVVKPSQPSQEQRLGAENTHTAGSSQIYA", "length": 402, "header": "tr|A0A8N7UVX5-1|A0A8N7UVX5_DANRE Isoform 1 of StAR-related lipid transfer protein 7, mitochondrial OS=Danio rerio OX=7955 GN=stard7 PE=4 SV=1 CANONICAL=A0A8N7UVX5-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UVX5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX5/entry#A0A8N7UVX5-1", "sequence": { "sequence": 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"https://alliancegenome.org/gene/FB:FBgn0032513#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8R1R3-1", "protein_name": "StAR-related lipid transfer protein 7, mitochondrial", "gene_name": "Stard7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFPRRPPATLAAWLAGARGGGLLSALANQCRFVTGLRVRRAQQIAQLYGRLYSESSRCALLGRFWRRLRGRPGHASVLMAALSGVFVWDEERIQEEELQRSINEMKRLEEMSNIFQSSGVENYPPEPKSPAGGNEKSKDKEEPWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDAVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQENNVMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAKATAPSPERKNEGSCGPARIEYA", "length": 373 }, "evidence": [ { "id": "RGD:1307613", "url": "https://alliancegenome.org/gene/RGD:1307613#orthology", "database": "AGR" }, { "id": "MGI:2139090", "url": "https://alliancegenome.org/gene/MGI:2139090#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2310", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2310#orthology", "database": "AGR" }, { "id": "HGNC:18063", "url": "https://alliancegenome.org/gene/HGNC:18063#orthology", "database": "AGR" }, { "id": "FB:FBgn0032513", "url": "https://alliancegenome.org/gene/FB:FBgn0032513#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NQZ5-1", "protein_name": "StAR-related lipid transfer protein 7, mitochondrial", "gene_name": "STARD7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPRRLLAAWLAGTRGGGLLALLANQCRFVTGLRVRRAQQIAQLYGRLYSESSRRVLLGRLWRRLHGRPGHASALMAALAGVFVWDEERIQEEELQRSINEMKRLEEMSNMFQSSGVQHHPPEPKAQTEGNEDSEGKEQRWEMVMDKKHFKLWRRPITGTHLYQYRVFGTYTDVTPRQFFNVQLDTEYRKKWDALVIKLEVIERDVVSGSEVLHWVTHFPYPMYSRDYVYVRRYSVDQENNMMVLVSRAVEHPSVPESPEFVRVRSYESQMVIRPHKSFDENGFDYLLTYSDNPQTVFPRYCVSWMVSSGMPDFLEKLHMATLKAKNMEIKVKDYISAKPLEMSSEAKATSQSSERKNEGSCGPARIEYA", "length": 370 }, "evidence": [ { "id": "RGD:1307613", "url": "https://alliancegenome.org/gene/RGD:1307613#orthology", "database": "AGR" }, { "id": "MGI:2139090", "url": "https://alliancegenome.org/gene/MGI:2139090#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2310", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2310#orthology", "database": "AGR" }, { "id": "HGNC:18063", "url": "https://alliancegenome.org/gene/HGNC:18063#orthology", "database": "AGR" }, { "id": "FB:FBgn0032513", "url": "https://alliancegenome.org/gene/FB:FBgn0032513#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VJZ2-1", "protein_name": "START domain-containing protein", "gene_name": "Stard7", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLFNRFVLAIKNQSRETLRAWSYQCESIFAQRSRRVQQLFSFYQSVYGTQGLKQLWRAYYRRELQPPLRGMVMSAVGLVGLNIKRMGSDGFDWNKERLALSNFDLCRRDIEFINALPNNQLCDRCQAKKMKYCYCQLGNQRCKKGQSQPSTSKEAETDPDTSISNCLRPLDLDVRNAPAGTVRIQAQDDQKWEPYFSKNEFSIWRRQERSSLYSYKVYARFDDITADDFLHVQTDLDYRRQWDDTALRLELISEDPVPGSNSHLIYWEMQWPRLFANRDYVYCRRYIKDDNKKLIFICNRGATHNTYPALSGKVRVTDYWSLMVIKPFRGFHEPGLHFVLTYFDDPGIPIPQNIKSWVTQKQMPEFLTKMYVATKNYACSRAIKMKDMFHGFALINDEYTANEQRGSWLGSLSRRKVNSKPEAGR", "length": 425 }, "evidence": [ { "id": "RGD:1307613", "url": "https://alliancegenome.org/gene/RGD:1307613#orthology", "database": "AGR" }, { "id": "MGI:2139090", "url": "https://alliancegenome.org/gene/MGI:2139090#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2310", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2310#orthology", "database": "AGR" }, { "id": "HGNC:18063", "url": "https://alliancegenome.org/gene/HGNC:18063#orthology", "database": "AGR" }, { "id": "FB:FBgn0032513", "url": "https://alliancegenome.org/gene/FB:FBgn0032513#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVX5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UVX5", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UVX5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UVX5" }, { "id": "PS50848", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50848" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "START", "eco_id": "ECO_0000259", "start_pos": 175, "end_pos": 364, "start_aa": "Asp", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UW24-1", "uniprot_ac": "A0A8N7UW24", "uniprot_id": "A0A8N7UW24_DANRE", "mass": { "chemical_mass": 21632.0, "monoisotopic_mass": 21632.0 }, "refseq": { "ac": "XP_697248", "name": "ras-related protein Rab-31 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697248" }, "gene_names": [ { "name": "rab31", "type": "recommended", "evidence": [ { "id": "A0A8N7UW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW24" } ] }, { "name": "rab31", "type": "synonym", "evidence": [ { "id": "XP_697248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697248" } ] } ], "protein_names": [ { "name": "small monomeric GTPase", "type": "recommended", "evidence": [ { "id": "A0A8N7UW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW24/entry#names_and_taxonomy" } ] }, { "name": "3.6.5.2", "type": "synonym", "evidence": [ { "id": "A0A8N7UW24", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW24/entry#names_and_taxonomy" } ] }, { "name": "ras-related protein Rab-31 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_697248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697248" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Feb 16, 2007 this sequence version replaced XP_697248.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_697248", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697248" } ] } ], "disease": [ { "disease_id": "DOID:2945", "recommended_name": { "id": "DOID:2945", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2945", "name": "severe acute respiratory syndrome", "description": "A Coronavirus infectious disease that results_in infection located_in respiratory tract, has_material_basis_in Severe acute respiratory syndrome coronavirus (SARS-CoV or SARS-CoV-1), a subtype of Betacoronavirus pandemicum, which is transmitted_by droplet spread of respiratory secretions, transmitted_by ingestion of contaminated food, or transmitted_by fomites. The infection has_symptom fever, has_symptom headache, has_symptom body aches, has_symptom dry cough, and has_symptom hypoxia." }, "synonyms": [ { "id": "DOID:2945", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2945", "name": "SARS", "description": "" }, { "id": "DOID:2945", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2945", "name": "SARS-CoV infection", "description": "" }, { "id": "MONDO:0005091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005091", "name": "severe acute respiratory syndrome", "description": "A viral respiratory infection caused by the SARS coronavirus. It is transmitted through close person-to-person contact. It is manifested with high fever, headache, dry cough and myalgias. It may progress to pneumonia and cause death." }, { "id": "MONDO:0005091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005091", "name": "SARS", "description": "" }, { "id": "MONDO:0005091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005091", "name": "SARS coronavirus caused disease or disorder", "description": "" }, { "id": "MONDO:0005091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005091", "name": "SARS coronavirus disease or disorder", "description": "" }, { "id": "MONDO:0005091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005091", "name": "SARS coronavirus infectious disease", "description": "" }, { "id": "MONDO:0005091", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005091", "name": "acute respiratory coronavirus infection", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "2945", "database": "AGR", "url": 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"MAIRELKVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFLTKTVPSGNELHKFLIWDTAGQERFHSLAPMYYRGSAAAVIVYDITKLDSFQTLKKWVKELKEHGPEDIVVAIAGNKNDLGDIREVPTKEAKEFAESIAAIFMETSARNAVNIEELFQKISRQIPPLENTDADSHDSFKLTRQPPPATKRCC", "length": 194, "header": "tr|A0A8N7UW24-1|A0A8N7UW24_DANRE Isoform 1 of small monomeric GTPase OS=Danio rerio OX=7955 GN=rab31 PE=3 SV=1 CANONICAL=A0A8N7UW24-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UW24-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW24/entry#A0A8N7UW24-1", "sequence": { "sequence": "MAIRELKVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFLTKTVPSGNELHKFLIWDTAGQERFHSLAPMYYRGSAAAVIVYDITKLDSFQTLKKWVKELKEHGPEDIVVAIAGNKNDLGDIREVPTKEAKEFAESIAAIFMETSARNAVNIEELFQKISRQIPPLENTDADSHDSFKLTRQPPPATKRCC", "length": 194, "header": "tr|A0A8N7UW24-1|A0A8N7UW24_DANRE Isoform 1 of small monomeric GTPase OS=Danio rerio OX=7955 GN=rab31 PE=3 SV=1 CANONICAL=A0A8N7UW24-1" }, "locus": {} }, { "isoform_ac": "A0AC58I072-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW24/entry#A0AC58I072-1", "sequence": { "sequence": "MYYRGSAAAVIVYDITKLDSFQTLKKWVKELKEHGPEDIVVAIAGNKNDLGDIREVPTKEAKEFAESIAAIFMETSARNAVNIEELFQKISRQIPPLENTDADSHDSFKLTRQPPPATKRCC", "length": 122, "header": "tr|A0AC58I072-1|A0AC58I072_DANRE Computationally mapped isoform of small monomeric GTPase OS=Danio rerio OX=7955 GN=rab31 PE=3 SV=1 CANONICAL=A0A8N7UW24-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 37, "start_aa": "Thr", "end_pos": 37, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr37", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], 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"length": 195 }, "evidence": [ { "id": "RGD:628598", "url": "https://alliancegenome.org/gene/RGD:628598#orthology", "database": "AGR" }, { "id": "HGNC:9771", "url": "https://alliancegenome.org/gene/HGNC:9771#orthology", "database": "AGR" }, { "id": "MGI:1914603", "url": "https://alliancegenome.org/gene/MGI:1914603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-13#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6GQP4-1", "protein_name": "Ras-related protein Rab-31", "gene_name": "Rab31", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMAIRELKVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNELHKFLIWDTAGQERFHSLAPMYYRGSAAAVIVYDITKQDSFHTLKKWVKELKEHGPENIVMAIAGNKCDLSDIREVPLKDAKEYAESIGALVVETSAKNAINIEELFQGISRQIPPLDPHENGNSGGIKLGNQSLQAGRRCC", "length": 195 }, "evidence": [ { "id": "RGD:628598", "url": "https://alliancegenome.org/gene/RGD:628598#orthology", "database": "AGR" }, { "id": "HGNC:9771", "url": "https://alliancegenome.org/gene/HGNC:9771#orthology", "database": "AGR" }, { "id": "MGI:1914603", "url": "https://alliancegenome.org/gene/MGI:1914603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-13#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q921E2-1", "protein_name": "Ras-related protein Rab-31", "gene_name": "Rab31", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMAIRELKVCLLGDTGVGKSSIVCRFVQDHFDHNISPTIGASFMTKTVPCGNELHKFLIWDTAGQERFHSLAPMYYRGSAAAVIVYDITKQDSFHTLKKWVKELKEHGPENIVMAIAGNKCDLSDIREVPLKDAKEYAESIGAIVVETSAKNAINIEELFQGISRQIPPLGPQENGNSGGIKLGNQSLQASRRCC", "length": 195 }, "evidence": [ { "id": "RGD:628598", "url": "https://alliancegenome.org/gene/RGD:628598#orthology", "database": "AGR" }, { "id": "HGNC:9771", "url": "https://alliancegenome.org/gene/HGNC:9771#orthology", "database": "AGR" }, { "id": "MGI:1914603", "url": "https://alliancegenome.org/gene/MGI:1914603#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-13#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW24", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW24" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW24", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW24" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW24", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW24" } ], "pmid": "" }, { "name": "phagocytic vesicle membrane", "id": "GO:0030670", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030670", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW24", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW24" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW24", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW24" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19669", "name": "", "equation": "GTP + H2O = GDP + phosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "A0AC58HEV8-1", "Q7SZ59-1", "Q6PHI9-1", "A0A8N7T7A2-1", "P79735-1", "B8JIV0-1", "Q5U3A7-1", "Q6TEN1-1", "Q7SXN5-1", "Q7ZVN5-1", "B0R0B1-1", "Q1MT80-1", "F1QGW6-1", "P79737-1", "Q68EK7-1", "Q6P3J5-1", "A0A2R8Q8S1-1", "A0AB32T9E2-1", "Q5U3E1-1", "A0JMI9-1", "A0A8M1RS74-1", "A0A8M1P339-1", "Q1LV74-1", "Q92005-1", "B7ZD40-1", "E7F144-1", "E7FBI4-1", "Q1L986-1", "A1DZY4-1", "Q6DGN0-1", "Q6P0U3-1", "A0AC58IWZ9-1", "Q08BB1-1", "Q6DHC1-1", "Q7T3A4-1", "Q501Z5-1", "A0A8M1PEV5-1", "A0AB32TD14-1", "Q6NVC5-1", "A0A8M1QHW9-1", "A0A8M2BCV1-1", "Q6NY89-1", "Q5RHR9-1", "A0A8M2BDC5-1", "A0AC58GC78-1", "Q32LU1-1", "A0AC58JL54-1", "A0A8M3BF01-1", "Q6PUR6-1", "A0A8M1PM05-1", "A5WW21-1", "Q6TNS7-1", "Q6ZM63-1", "A0A8M1N0T3-1", "A0AC58GWJ0-1", "A0A8N7UW24-1", "A0AC58IQZ8-1", "A0A8M3AJE6-1", "A0AC58GZD6-1", "A0AC58GZ98-1", "A0A2R8QLH1-1", "A0AC58IDY2-1", "A0A8M2BBB3-1", "A0AC58IZ11-1", "A0AC58JFB1-1", "Q6DHE8-1", "Q7T2E8-1", "Q6DHM9-1", "A0AB32TXV7-1", "Q6NUX8-1", "A0A8M6YYL0-1", "A0ACD6B5W7-1" ], "evidence": [ { "id": "19669", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19669" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A2R8Q8S1", "gene_name": "kras", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A2R8Q8S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A2R8Q8S1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A2R8Q8S1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A2R8Q8S1" } ] } ] }, { "uniprot_ac": "A0A2R8QLH1", "gene_name": "rab41", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A2R8QLH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A2R8QLH1" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A2R8QLH1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A2R8QLH1" } ] } ] }, { "uniprot_ac": "A0A8M1N0T3", "gene_name": "rab40b", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8M1N0T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N0T3" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8M1N0T3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1N0T3" } ] } ] }, { "uniprot_ac": "A0A8M1P339", "gene_name": "rerg", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8M1P339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1P339" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8M1P339", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1P339" } ] } ] }, { "uniprot_ac": "A0A8M1PEV5", "gene_name": "rab14l", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8M1PEV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PEV5" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8M1PEV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PEV5" } ] } ] }, { "uniprot_ac": "A0A8M1PM05", "gene_name": "rab20", "activity": [ { "ec_number": "3.6.5.2", "activity": "GTP + H2O = GDP + phosphate + H(+).", "evidence": [ { "id": "A0A8M1PM05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PM05" } ] }, { "ec_number": "3.6.5.2", "activity": "", "evidence": [ { "id": "A0A8M1PM05", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PM05" } ] } ] }, { "uniprot_ac": "A0A8M1QHW9", 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commonly nystagmus and saccadic abnormalities." }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "ATXN1 autosomal dominant cerebellar ataxia type I", "description": "" }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "SCA1", "description": "" }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "Sca1", "description": "" }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "autosomal dominant cerebellar ataxia type I caused by mutation in ATXN1", "description": "" }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "spinocerebellar ataxia type 1", "description": "" }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "OPCA1", "description": "" }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "OPCA4", "description": "" }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "spinocerebellar ataxia 1", "description": "" }, { "id": "MIM:164400", "resource": "MIM", "url": "https://www.omim.org/entry/164400", "name": "Spinocerebellar ataxia 1", "description": "Spinocerebellar ataxia 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "1441", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1441" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UW40", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW40" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zmp:0000000926", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW40", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-929", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-929", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "571706", "url": "https://www.ncbi.nlm.nih.gov/gene/571706", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043404", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043404", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:571706", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571706", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UW40", "url": "https://www.orthodb.org/?gene=A0A8N7UW40", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13392", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13392", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13392:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13392:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_068072921", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068072921", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UW40", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW40", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UW40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW40-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-929", "url": "https://zfin.org/ZDB-GENE-130530-929", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNPSPDRSKECLPPKKRESRQGSTDQPAPEDDFKPPAPFRSRRPHQPTEGPREGGDLLPPVPLPLPWPVSYTPSIHPHTYLPLQLGERRGSWREALCGRGVDGGLEQSVPQHSRWLSSDIPHINMQPLLSVPTFKSVYSGDSREMWSCGLSRPDYSSSLFSPHVFPQPAVYPPDSLPDSRLRYQSRRHNGIDGQDCKSGFSRRVPSCNDYGNDSVSRLDAPHANGRRRQENTSRQTPEKRLPPQVSTSAHSSPWDRDPRGTPKASMPPSPDTKAGKAITSQDHFGGSASPAGAQIYYTLGSLCPSAQQNPQVFPQPRSPLSCSARSSQNQHNSHGVETDWSSPAGPCRPPLAVLMGPDPPPSAVLPHFAKGSLIELAGGHLKRVEELKTEDFLRSADTLPEFHLSSCTILLISPGPTYGFNHLQVLLTDRNTQELLTVLSEYPFFVRDRGWSSCSPQRSAQLYGLQCRQLSTGDVCLALTPTPTHKPNLAPSESRGPPGGSREPPSGTELQNTHRPRKRRWSAPELEPGAQTHTHSPLPQHSHTHH", "length": 546, "header": "tr|A0A8N7UW40-1|A0A8N7UW40_DANRE Isoform 1 of Uncharacterized protein zmp:0000000926 OS=Danio rerio OX=7955 GN=zmp:0000000926 PE=4 SV=2 CANONICAL=A0A8N7UW40-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UW40-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UW40/entry#A0A8N7UW40-1", "sequence": { "sequence": "MNPSPDRSKECLPPKKRESRQGSTDQPAPEDDFKPPAPFRSRRPHQPTEGPREGGDLLPPVPLPLPWPVSYTPSIHPHTYLPLQLGERRGSWREALCGRGVDGGLEQSVPQHSRWLSSDIPHINMQPLLSVPTFKSVYSGDSREMWSCGLSRPDYSSSLFSPHVFPQPAVYPPDSLPDSRLRYQSRRHNGIDGQDCKSGFSRRVPSCNDYGNDSVSRLDAPHANGRRRQENTSRQTPEKRLPPQVSTSAHSSPWDRDPRGTPKASMPPSPDTKAGKAITSQDHFGGSASPAGAQIYYTLGSLCPSAQQNPQVFPQPRSPLSCSARSSQNQHNSHGVETDWSSPAGPCRPPLAVLMGPDPPPSAVLPHFAKGSLIELAGGHLKRVEELKTEDFLRSADTLPEFHLSSCTILLISPGPTYGFNHLQVLLTDRNTQELLTVLSEYPFFVRDRGWSSCSPQRSAQLYGLQCRQLSTGDVCLALTPTPTHKPNLAPSESRGPPGGSREPPSGTELQNTHRPRKRRWSAPELEPGAQTHTHSPLPQHSHTHH", "length": 546, "header": "tr|A0A8N7UW40-1|A0A8N7UW40_DANRE Isoform 1 of Uncharacterized protein zmp:0000000926 OS=Danio rerio OX=7955 GN=zmp:0000000926 PE=4 SV=2 CANONICAL=A0A8N7UW40-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 417, "start_aa": "Thr", "end_pos": 417, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr417", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 482, "start_aa": "Thr", "end_pos": 482, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr482", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:571706", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571706", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AA52Z3H5-1", "protein_name": "Ataxin-1a isoform X1", "gene_name": "atxn1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPASTLPSEEKPMVMAPANESQRGGNLAWLASLASGHDKGRLHTSTSAESDGPQYKPLSATAESTPSSSTHSTRALSAVTTIPAVYTSPLSHSPSAIQYTPLPHNIHFINPPYSAPYAGYISPLAPPLAATTTTQREIYASSSSSPASKIDQHHQLGRPQGLVTTDNTSSPHSTQYVQIAGSPLSISPRTVSSPHTHLPLHLHPHHTLPLSGPSQVLVPYTESLLPKREEMRTRELLNGELEKDRRFGPSSESSAGKQGSTAKGGSSAQQHQIHQQQSPRHFEARHVVLPAEYTQDSTAMRTSLVLVPNNHSSTSADSGGASDKLPPSTSHHEKGGICAGKPVSRSSSLSSSLSFALPPPPVDNLKGAVPAQSPHAVIQTTLNSTESLSLSLPSTNFYSTQQPIIGYFAGTGHQQPLSYHTTLPQHLVIPGTQPVIIPVSGTEATATSTAALPHAFVTSTAPKVETFESPAPYPHPATAMVQAQLHLPVVPAPAGLLTTPPPPSAPSMPPYFTKGSIIQLADGELKRVEDLKTEDFIQSAEISNELKIDSSTVERIDSSHTANFAIIQFAVGAQRSQVSVEVLVEYPFFVFGQGWSSCCPDRTTQLLELPCTKLSVGDVCISLTLKNLRNGSIKKSQGQVLDAPALGPPLKSPKALSSGARGGVRHTEQENGLGQCADQGSRGGQGNRENGELRFGERDNCKAPTLTESETSSKPTGRKRRWSAPEGRKVENPEGEPPLTFPKPSFIPQEVKISIEGRSNIGK", "length": 781 }, "evidence": [ { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZBC4-1", "protein_name": "Ataxin 1 like", "gene_name": "Atxn1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKPVHERSQECLPPKKRDLPVTSCSTNHTPSSDASEWSRGVVVAGQSQTGARVSLGGDGTEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPVHYAQLPSTSLQFIGSPYSLPYAVPPNFLPNPLLSPSANLATTHLPHFVPYASLLAEEAAPPPQAASPAQSFTKSSSATSPPGQLPHHSNTQPLDLAPGRMPIYYQTSRLPAGYTLHETSTAGASPILTPQEGQSALEAAAANGQRQRERSVRRESEPLDSTSSKGESQGLVPVVECMVDGQLFSGSQTPRVEVAAPTHRGTPDTDLEVQRVVGALASQDYRVVAAQRKDEPSPLNLSHHTLDHQGEGRGSARNPTEVVEKNQTRVFYPQSHQEPVKHRPLPKAVVVANGNLVPTGTDPSLLPVGSEILVASSLDMQARATFPDKEPTPPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPGQLGTPRERPERTILGPRDLCDSEGKNQTSGEGSRVGEPSQPEPSAQACWPAPSFQRYSMQGEEARAALLRPSFIPQEVKLSIEGRSNAGK", "length": 679 }, "evidence": [ { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7F6Z5-1", "protein_name": "Ataxin-1", "gene_name": "atxn1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKSNQERCNECLPPKKREILALEEKQVLVSAAVSESQSGENLAWLASVATMASMAHIPNNAGPSHSNSSEPDSPPPSNKALTVVAEYPPTTTSAGFSFSSNSSTYRGVLSGPTVLTASPAVLSTSLPQTIGSVQYTQLPPNLQLIGPYTSYISSHIVPSTSSPTQPQRTPQEILATTAVISQASSLDSQSHVISSIPNVSHSQCIQVESAPLGLTVSSPSTQLPLQIHPHSAVLAPHALALTPSQVVLHYTDGFIAKQPDSHRREVLNGALGDVTVVKHNTTMAKGISSQPDVEQNHKQNHNLGIQTQAQVLLPADYTTNDRAGLQTSLMLVSSSHLAANSNSDIQSILGKDHSSLHLAERGGICLGKPMSRVSSLTSSDSQVSPASTISPHTLIQAPHNAPQQELSTSLYSATQLPIIGYITSASGGPQQAVTGYQSNLPQHVVISGNPSLLIPVSATNINPSTAEPEVTRCSVIPSLANASTALPQTFINTSPPAAVASVLPNGKDITGSDGGLVPCAVPSPTQIQLPVLSGSVVRSPVPATPPISTSPHSSPSSPTAGLPPFFMKGSIIQLADGELKRVEDLRTEDFVQSAEVSGELKIDSSTVERIEGSGTPNAVIIQFSVGENKAQVCVEVLVEYPFFVFGQGWSSCCPDRTTQLLALSCAKLSVGDVCISLTLKSLKNSIQKKDHFSDSVMKHSLLNATKNNGPLMERPTQVDDLKKGHKIPSEVENSIVEKLIETSNTKIVLSLSENGGSNPQTLVNLQNQAEKTYTSTAERPISRKRRWSAPEKADMQKSREDPQILPKFSFIPHQLKVSIEGRSSTGC", "length": 827 }, "evidence": [ { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P0C7T5-1", "protein_name": "Ataxin-1-like", "gene_name": "ATXN1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWSRGVVVAGQSQAGARVSLGGDGAEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPLHYAQLPSTSLQFIGSPYSLPYAVPPNFLPSPLLSPSANLATSHLPHFVPYASLLAEGATPPPQAPSPAHSFNKAPSATSPSGQLPHHSSTQPLDLAPGRMPIYYQMSRLPAGYTLHETPPAGASPVLTPQESQSALEAAAANGGQRPRERNLVRRESEALDSPNSKGEGQGLVPVVECVVDGQLFSGSQTPRVEVAAPAHRGTPDTDLEVQRVVGALASQDYRVVAAQRKEEPSPLNLSHHTPDHQGEGRGSARNPAELAEKSQARGFYPQSHQEPVKHRPLPKAMVVANGNLVPTGTDSGLLPVGSEILVASSLDVQARATFPDKEPTPPPITSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTTQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPSQLGPPRERPERTVLGSRELCDSEGKSQPAGEGSRVVEPSQPESGAQACWPAPSFQRYSMQGEEARAALLRPSFIPQEVKLSIEGRSNAGK", "length": 689 }, "evidence": [ { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P0C7T6-1", "protein_name": "Ataxin-1-like", "gene_name": "Atxn1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKPVHERSQECLPPKKRDLPVTSEDMGRTTSCSTNHTPSSDASEWSRGVVVAGQSQTGARVSLGGDGTEAITGLTVDQYGMLYKVAVPPATFSPTGLPSVVNMSPLPPTFNVASSLIQHPGIHYPPVHYAQLPSTSLQFIGSPYSLPYAVPPNFLPSPLLSPSANLATTHLPHFVPYASLLAEEATPPPQAASPAQSFNKSSSATSPPGQLPHHSNTQPLDLAPGRMPIYYQMSRLPAGYTLHETSTAGASPILTPQEGQSALEAAAANGQRQRERNVRRESEALDSASSKGESQGLVPVVECMADGQLFSGSQTPRVEVAAPAHRGTPDTDLEVQRVVGALASQDYRVVAAQRKDEPSPLNLSHHNLDHQGEGRGSARNPTELVEKSQARVFYPQSHQEPVKHRPLPKAMVVANGNLVPTGTDPSLLPVGSEILVASSLDLQARATFPDKEPTPPPVTSSHLPSHFMKGAIIQLATGELKRVEDLQTQDFVRSAEVSGGLKIDSSTVVDIQESQWPGFVMLHFVVGEQQSKVSIEVPPEHPFFVYGQGWSSCSPGRTAQLFSLPCHRLQVGDVCISISLQSLNSNSVSQASCAPPGQLGTPRERPERTVLGPRDLCDSEGKNQPSGEGSRVGEPSQPEPGAQACWPAPSFQRFSMQGEEARAAMLRPSFIPQEVKLSIEGRSNAGK", "length": 687 }, "evidence": [ { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P54253-1", "protein_name": "Ataxin-1", "gene_name": "ATXN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSRSSEEKAPTLPSDNHRVEGTAWLPGNPGGRGHGGGRHGPAGTSVELGLQQGIGLHKALSTGLDYSPPSAPRSVPVATTLPAAYATPQPGTPVSPVQYAHLPHTFQFIGSSQYSGTYASFIPSQLIPPTANPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQTPGHKAEQQQQQQQQQQQQHQHQQQQQQQQQQQQQQHLSRAPGLITPGSPPPAQQNQYVHISSSPQNTGRTASPPAIPVHLHPHQTMIPHTLTLGPPSQVVMQYADSGSHFVPREATKKAESSRLQQAIQAKEVLNGEMEKSRRYGAPSSADLGLGKAGGKSVPHPYESRHVVVHPSPSDYSSRDPSGVRASVMVLPNSNTPAADLEVQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGSLPQHLVIPGTQPLLIPVGSTDMEASGAAPAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPAAAPPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKHSKADGLAGSRHRYAEQENGINQGSAQMLSENGELKFPEKMGLPAAPFLTKIEPSKPAATRKRRWSAPESRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK", "length": 815 }, "evidence": [ { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54254-1", "protein_name": "Ataxin-1", "gene_name": "Atxn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSRPSEEKATALPSDNHCVEGVAWLPSTPGIRGHGGGRHGSAGTSGEHGLQGMGLHKALSAGLDYSPPSAPRSVPTANTLPTVYPPPQSGTPVSPVQYAHLSHTFQFIGSSQYSGPYAGFIPSQLISPSGNPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQAPGHKVEPPPQQHLSRAAGLVNPGSPPPPTQQNQYIHISSSPQSSGRATSPPPIPVHLHPHQTMIPHTLTLGPSSQVVVQYSDAGGHFVPRESTKKAESSRLQQAMQAKEVLNGEMEKSRRYGASSSVELSLGKASSKSVPHPYESRHVVVHPSPADYSSRDTSGVRGSVMVLPNSSTPSADLEAQQTTHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGTQPPVIGYLSGQQQAITYAGGLPQHLVIPGNQPLLIPVGSPDMDTPGAASAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPTTASPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEESHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASVLLKQAKTDSLAGSRHRYAEQENGINQGSAQVLSENGELKFPEKIGLPAAPFLSKIEPSKPTATRKRRWSAPETRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK", "length": 791 }, "evidence": [ { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q63540-1", "protein_name": "Ataxin-1", "gene_name": "Atxn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKSNQERSNECLPPKKREIPATSRPSEEKATALPSDNHCVEGVAWLPSTPGSRGHGGGRHGPAGTSGEHGLQGMGLHKALSAGLDYSPPSAPRSVPTANTLPTVYPPPQSGTPVSPVQYAHLSHTFQFIGSSQYSGPYAGFIPSQLISPPGNPVTSAVASAAGATTPSQRSQLEAYSTLLANMGSLSQAPGHKVEPPPQQHLGRAAGLVNPGSPPPTQQNQYIHISSSPQSSGRATSPPIPVHLHPHQTMIPHTLTLGPSSQVVVQYSDAGGHFVPRESTKKAESSRLQQAMQAKEVLNGEMEKSRRYGASSSVELSLGKTSSKSVPHPYESRHVVVHPSPADYSSRDTSGVRGSVMVLPNSSTPSADLETQQATHREASPSTLNDKSGLHLGKPGHRSYALSPHTVIQTTHSASEPLPVGLPATAFYAGAQPPVIGYLSSQQQAITYAGGLPQHLVIPGTQPLLIPVGSPDMDTPGAASAIVTSSPQFAAVPHTFVTTALPKSENFNPEALVTQAAYPAMVQAQIHLPVVQSVASPAAASPTLPPYFMKGSIIQLANGELKKVEDLKTEDFIQSAEISNDLKIDSSTVERIEDSHSPGVAVIQFAVGEHRAQVSVEVLVEYPFFVFGQGWSSCCPERTSQLFDLPCSKLSVGDVCISLTLKNLKNGSVKKGQPVDPASALLKHAKTDSLAGSRHRYAEQENGINQGSAQVLSENGELKFPEKIGLPAAPFLTKIEPSKPTATRKRRWSAPETRKLEKSEDEPPLTLPKPSLIPQEVKICIEGRSNVGK", "length": 789 }, "evidence": [ { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9W3V7-1", "protein_name": "Ataxin 1", "gene_name": "Atx-1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQMHMELSYGRGYDPIGRQPPSLPPPSQQHWSSNGFSDDSASCFRRGSYIELASGAMRRVEDIRTEDFIQSALRSQLFELREATVVRIDWSGCPSLVTLTFSYDTHHAKMDLQVQPGHPMFVYGQGWASCDPQLSLQLYELKCQQLQVGDICLSLVPNEQPAAPCPPQPAPPPPCPPPSLPPSMEMPVPMGSPPTGSYGFLPFKHPYEMYAQMASFVAVYTQHMMGKLNY", "length": 230 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-130530-929", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-929#orthology", "database": "AGR" }, { "id": "FB:FBgn0029907", "url": "https://alliancegenome.org/gene/FB:FBgn0029907#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of transcription by RNA polymerase II", "id": "GO:0000122", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000122", "evidence": [ { 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The reference sequence was derived from JBMGRA010000005.1. 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The reference sequence was derived from JBMGRA010000004.1. On Jul 31, 2008 this sequence version replaced XP_001923402.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001121827", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121827" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZ16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ16" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC794656", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ16", "locus": {} } ], "crossref": [ { "id": "A0A8N7UZ16", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UZ16", "database": "AlphaFoldDB", "categories": [] }, { "id": "794656", "url": "https://www.ncbi.nlm.nih.gov/gene/794656", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029495", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029495", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041075", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041075", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:794656", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:794656", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UZ16", "url": "https://www.orthodb.org/?gene=A0A8N7UZ16", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14484", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14484", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17779", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17779", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001121827", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121827", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UZ16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ16", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UZ16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ16-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAEERVKGSLSEKHSVRSGSFVSSSVSLKSDWSKGGPPPDLRGKTPSSVKSVRSGSCVSSSVSLKSDWSMGHLPPDLREKTPSSARRHLVADLVSYSDNLQWIFQNLESKMIRFLKNQLENFRKILQHKNRQEFIKEFIENRSILTEAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRPHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFLPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLKESPKTLTQMYTHFLRFQIQQSRRKFDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETRIILGTMYCFLHLSIQEFIAALYQHLHSERIYF", "length": 597, "header": "tr|A0A8N7UZ16-1|A0A8N7UZ16_DANRE Isoform 1 of Uncharacterized protein LOC794656 OS=Danio rerio OX=7955 GN=LOC794656 PE=4 SV=1 CANONICAL=A0A8N7UZ16-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UZ16-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ16/entry#A0A8N7UZ16-1", "sequence": { "sequence": "MAEERVKGSLSEKHSVRSGSFVSSSVSLKSDWSKGGPPPDLRGKTPSSVKSVRSGSCVSSSVSLKSDWSMGHLPPDLREKTPSSARRHLVADLVSYSDNLQWIFQNLESKMIRFLKNQLENFRKILQHKNRQEFIKEFIENRSILTEAALDLTLFFLREMKQDQAADTLQGELFFINQLKCSLKKKYQSVFEGIAQQGDSTLLNNIYTDLYITQGASEQVNTEHEIRQIEAASRPHQSLEIQVECKHLFEAAEQDERIRTVLTKGVAGIGKSVSVQKFVLDWAEGKENQDISFIFPLPFREMNLKEKERQSLKDLITQFLPETKGLNLTRSTRFKVLFILDGLDECRLPLNFAGNETCRDVSSAVSLDVLLTNLIKGNLLPSALIWITSRPAAASKIPADCIDRLTEIRGFNDAQKEEYFRKRLTDQNQAREIIDHIKQSKSLFIMCHIPVFCWISATVLQNILKLKHRAHAETLKESPKTLTQMYTHFLRFQIQQSRRKFDGENTADVSWDPKLILSLGKLAFQQLERNNVIFYESDLKDCGIDVYKASVYSGMCTQIFKKETRIILGTMYCFLHLSIQEFIAALYQHLHSERIYF", "length": 597, "header": "tr|A0A8N7UZ16-1|A0A8N7UZ16_DANRE Isoform 1 of Uncharacterized protein LOC794656 OS=Danio rerio OX=7955 GN=LOC794656 PE=4 SV=1 CANONICAL=A0A8N7UZ16-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:794656", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:794656", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZ16", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ16" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UZ16", "database": "UniProtKB", "url": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A0A8N7UZ82-1", "uniprot_ac": "A0A8N7UZ82", "uniprot_id": "A0A8N7UZ82_DANRE", "mass": { "chemical_mass": 19763.0, "monoisotopic_mass": 19763.0 }, "refseq": { "ac": "NP_001138280", "name": "uncharacterized protein LOC100126138 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138280" }, "gene_names": [ { "name": "si:ch211-12h2.8", "type": "recommended", "evidence": [ { "id": "A0A8N7UZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ82" } ] }, { "name": "si:ch211-12h2.8", "type": "synonym", "evidence": [ { "id": "NP_001138280", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138280" } ] }, { "name": "si:dkeyp-98a7.10", "type": "synonym", "evidence": [ { "id": "NP_001138280", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138280" }, { "id": "A0A8N7UZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ82" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100126138 precursor", "type": "synonym", "evidence": [ { "id": "A0A8N7UZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ82/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100126138 precursor", "type": "synonym", "evidence": [ { "id": "NP_001138280", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138280" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH453476.1, EH483879.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898399, SAMEA898400 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH543751.1 and EH479250.1. On Mar 13, 2013 this sequence version replaced NP_001138280.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001138280", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138280" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZ82", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ82" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-12h2.8", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ82", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091118-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-43", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UZ82", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UZ82", "database": "AlphaFoldDB", "categories": [] }, { "id": "100126138", "url": "https://www.ncbi.nlm.nih.gov/gene/100126138", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100126138", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100126138", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UZ82", "url": "https://www.orthodb.org/?gene=A0A8N7UZ82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001138280", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138280", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UZ82", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UZ82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091118-43", "url": "https://zfin.org/ZDB-GENE-091118-43", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFLLSLFLTMILLNSSLLISAGRGGHDGGHDGHSHGGHNGHSHGGHDGHSHGGHGGHDGHYHGGHDHDGHDNDYCRRSTDTKTACEGSVLHLSCPDHFKIKILAANYGRTDRTTCVDYHPWREIKKTDCYSYHCLTDVSARCDGRKSCSIPATNGEFSDPCYGTYKYLRVKYCCKRPRS", "length": 179, "header": "tr|A0A8N7UZ82-1|A0A8N7UZ82_DANRE Isoform 1 of Uncharacterized protein LOC100126138 precursor OS=Danio rerio OX=7955 GN=si:ch211-12h2.8 PE=1 SV=1 CANONICAL=A0A8N7UZ82-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UZ82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ82/entry#A0A8N7UZ82-1", "sequence": { "sequence": "MFLLSLFLTMILLNSSLLISAGRGGHDGGHDGHSHGGHNGHSHGGHDGHSHGGHGGHDGHYHGGHDHDGHDNDYCRRSTDTKTACEGSVLHLSCPDHFKIKILAANYGRTDRTTCVDYHPWREIKKTDCYSYHCLTDVSARCDGRKSCSIPATNGEFSDPCYGTYKYLRVKYCCKRPRS", "length": 179, "header": "tr|A0A8N7UZ82-1|A0A8N7UZ82_DANRE Isoform 1 of Uncharacterized protein LOC100126138 precursor OS=Danio rerio OX=7955 GN=si:ch211-12h2.8 PE=1 SV=1 CANONICAL=A0A8N7UZ82-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZ82", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ82" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100126138", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100126138", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZ82", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ82" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UZ82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZ82" }, { "id": "PS50228", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUEL-type lectin", "eco_id": "ECO_0000259", "start_pos": 84, "end_pos": 175, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0A8N7UZA2-1", "uniprot_ac": "A0A8N7UZA2", "uniprot_id": "A0A8N7UZA2_DANRE", "mass": { "chemical_mass": 103501.0, "monoisotopic_mass": 103501.0 }, "refseq": { "ac": "NP_001139258", "name": "deoxynucleotidyltransferase terminal-interacting protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139258" }, "gene_names": [ { "name": "dnttip2", "type": "recommended", "evidence": [ { "id": "A0A8N7UZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2" } ] }, { "name": "cb88", "type": "synonym", "evidence": [ { "id": "NP_001139258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139258" }, { "id": "A0A8N7UZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2" } ] }, { "name": "dnttip2", "type": "synonym", "evidence": [ { "id": "NP_001139258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139258" } ] }, { "name": "sb:cb1016", "type": "synonym", "evidence": [ { "id": "NP_001139258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139258" }, { "id": "A0A8N7UZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2" } ] }, { "name": "sb:cb88", "type": "synonym", "evidence": [ { "id": "NP_001139258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139258" }, { "id": "A0A8N7UZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2" } ] } ], "protein_names": [ { "name": "Deoxynucleotidyltransferase terminal-interacting protein 2", "type": "synonym", "evidence": [ { "id": "A0A8N7UZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2/entry#names_and_taxonomy" } ] }, { "name": "deoxynucleotidyltransferase terminal-interacting protein 2", "type": "synonym", "evidence": [ { "id": "NP_001139258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139258" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01008896.1, GDQH01006210.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000008.1, EB864128.1, CT670422.2, CV487686.1 and BC142742.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001139258", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139258" } ] }, { "annotation": "Dnttip2 is essential for 18S rRNA processing and digestive organ development in zebrafish.", "evidence": [ { "database": "RefSeq", "id": "NP_001139258", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139258" }, { "database": "PubMed", "id": "38564939", "url": "https://glygen.org/publication/PubMed/38564939" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZA2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dnttip2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080513-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080513-5", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UZA2", "url": "https://alphafold.ebi.ac.uk/entry/A0A8N7UZA2", "database": "AlphaFoldDB", "categories": [] }, { "id": "564961", "url": "https://www.ncbi.nlm.nih.gov/gene/564961", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR014810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564961", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564961", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8N7UZA2", "url": "https://www.orthodb.org/?gene=A0A8N7UZA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21686", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21686", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21686:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21686:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08698", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08698", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001139258", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139258", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UZA2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UZA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080513-5", "url": "https://zfin.org/ZDB-GENE-080513-5", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVATRRGTRAGSPVKNTSDENSENAKKPTPSTRRTRRKTLTEENQSQSDSQPDEPKDDSTASSLASPPKKDTRRSTRLTVNKKQPDSTHEADVSESESCCSVASGVQPTPRTRRRTAVRDKRTIEEEASEAESCSSAASATHSRTAPRSLRKRVLTSASAKDADASGAESCSSAVSLTKGTDTQRMTRSHQKTAVPTRDADQSEPESCSSSVSGLRGSVVRRSTRNQKVTVTEPIPLNLEETTDAPSSPVSRKPRGRRRKTEGNDDESDGCKSGPSMSPWRSLRRQPKGDTIVGESDSESVATDVCTSHGSPSPQRGRGTPCSSRTGSASSNRAVPASRTRSKAKVITSAMSEEQSEDEQLVTHHEGIQAPEEQLDQTMTMETSEAQESTMIEEGAEDTTIVEDEPVEMLEVQSSSKEVKKIEDHGIIMKETGTETSLKEAEFMETLSESVVEATSKVPEKVDEAIEDQTCAEPVKEDAIHEDAVMVEDASEPEKAGSNQKDTEMIEVQTCPEPAKEETTEEASVMVKEDAEFQTSLEPSKEETIQTNVALIEEAQTSAEPAEKVKVTSDDPEPAVIEEKKGVTVTEESNELIKTTDDDSDAGPSTSSNTRVDLSTAEESSKEHPAQKEMISLLDSSDEEDSGDEGLSAEEEGGSQEDEDDLICPDDEPMPEEAEAHGNGLFVIDTRPGLRPEDQYYVDAKQTEEEDEEEDYVDEEGDDEDDEDSKVLFAPKKPLMQLSTSIDTGLKLKELGGLYVSFDGNKPKTLSRVLKAQKDVGGQDELLKKSVIIPGFEKMDAVPPCRESKHAAKLKRKAEREKTTGDGWFNMRAPELTEELKNDLKALKMRAAMDPKRFYKKNDREGFPKYFQVGTVVDSPVDFYNSRMAKKQRKRTIVEELLADAEFRSSNKRRYQEIMAEKAAQAAGKQHRKKHTKFSKKKTNK", "length": 941, "header": "tr|A0A8N7UZA2-1|A0A8N7UZA2_DANRE Isoform 1 of Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Danio rerio OX=7955 GN=dnttip2 PE=1 SV=1 CANONICAL=A0A8N7UZA2-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UZA2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2/entry#A0A8N7UZA2-1", "sequence": { "sequence": "MVATRRGTRAGSPVKNTSDENSENAKKPTPSTRRTRRKTLTEENQSQSDSQPDEPKDDSTASSLASPPKKDTRRSTRLTVNKKQPDSTHEADVSESESCCSVASGVQPTPRTRRRTAVRDKRTIEEEASEAESCSSAASATHSRTAPRSLRKRVLTSASAKDADASGAESCSSAVSLTKGTDTQRMTRSHQKTAVPTRDADQSEPESCSSSVSGLRGSVVRRSTRNQKVTVTEPIPLNLEETTDAPSSPVSRKPRGRRRKTEGNDDESDGCKSGPSMSPWRSLRRQPKGDTIVGESDSESVATDVCTSHGSPSPQRGRGTPCSSRTGSASSNRAVPASRTRSKAKVITSAMSEEQSEDEQLVTHHEGIQAPEEQLDQTMTMETSEAQESTMIEEGAEDTTIVEDEPVEMLEVQSSSKEVKKIEDHGIIMKETGTETSLKEAEFMETLSESVVEATSKVPEKVDEAIEDQTCAEPVKEDAIHEDAVMVEDASEPEKAGSNQKDTEMIEVQTCPEPAKEETTEEASVMVKEDAEFQTSLEPSKEETIQTNVALIEEAQTSAEPAEKVKVTSDDPEPAVIEEKKGVTVTEESNELIKTTDDDSDAGPSTSSNTRVDLSTAEESSKEHPAQKEMISLLDSSDEEDSGDEGLSAEEEGGSQEDEDDLICPDDEPMPEEAEAHGNGLFVIDTRPGLRPEDQYYVDAKQTEEEDEEEDYVDEEGDDEDDEDSKVLFAPKKPLMQLSTSIDTGLKLKELGGLYVSFDGNKPKTLSRVLKAQKDVGGQDELLKKSVIIPGFEKMDAVPPCRESKHAAKLKRKAEREKTTGDGWFNMRAPELTEELKNDLKALKMRAAMDPKRFYKKNDREGFPKYFQVGTVVDSPVDFYNSRMAKKQRKRTIVEELLADAEFRSSNKRRYQEIMAEKAAQAAGKQHRKKHTKFSKKKTNK", "length": 941, "header": "tr|A0A8N7UZA2-1|A0A8N7UZA2_DANRE Isoform 1 of Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Danio rerio OX=7955 GN=dnttip2 PE=1 SV=1 CANONICAL=A0A8N7UZA2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 109, "start_aa": "Thr", "end_pos": 109, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr109", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 29, "start_aa": "Thr", "end_pos": 29, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr29", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Hematopoietic gene expression profile in zebrafish kidney marrow.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2004", "authors": "Song Huai-Dong, Sun Xiao-Jian, Deng Min, Zhang Guo-Wei, Zhou Yi, Wu Xin-Yan, Sheng Yan, Chen Yi, Ruan Zheng, Jiang Chun-Lei, Fan Hui-Yong, Zon Leonard I, Kanki John P, Liu Ting Xi, Look A Thomas, Chen Zhu", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZA2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2" } ], "reference": [ { "type": "PubMed", "id": "15520368", "url": "https://glygen.org/publication/PubMed/15520368" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZA2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Dnttip2 is essential for 18S rRNA processing and digestive organ development in zebrafish.", "journal": "Biochem. Biophys. Res. Commun.", "date": "2024", "authors": "Zhou Ru, Cui Wei, Zeng Ni, Su Baochun, Chen Yayue, Shi Hui, Zhao Shuyi", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZA2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2" }, { "database": "RefSeq", "id": "NP_001139258", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139258" } ], "reference": [ { "type": "PubMed", "id": "38564939", "url": "https://glygen.org/publication/PubMed/38564939" } ] } ], "pathway": [ { "id": "dre:564961", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564961", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZHM7-1", "protein_name": "Deoxynucleotidyltransferase, terminal, interacting protein 2", "gene_name": "Dnttip2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVVTRSGSRIQESSQRKRSVPRRIGTHPESKKESGSKGSTAGSQSAEEQNSALSGSRNSRTAGPAEITVLISDGEASETESHASGVSSVLEVQEPIIRVTRKRQVVIVPTPKSSVRKRQKVIPQLPQHESGDEGAVSEAESHVSGVSMVVPSTERRTRNKAKSQRDSSQESYSETISDAEWSCSGISSLESAPRRTGRNVQKKLEFQAEKKDTEITPGNKKPIVGPSVDSEDSEAKQPSQLSSARLQSQINMPTISDSETYNNDFDDSIHRNSGEKLTTQNQNLHIQEEKQADVVSLTEVIKNCKNLDEEDPKVIEEKVVNEEDSQLSLSKAQDSSPQQSVSLKHSSIPRKATSQASSPEQEAVMKSLEHKFAVVKIERCNKERGGNVEKSDLAQFSDCGNSNDEPASVGVSEDKSSQRDVALECDAMPCKSELSMSRHTDSPILLFLSSDESQQSDSSENERDTLCPVENSGQKEASAEDLEDPACGSALFVIDRTPGLSADKNFYLEDKTPSEAAIEEEKEEEDEEGEEENSEDSSDGDEKKDESSDEEDFLSSTKSKLLKLTSSSIDPGLNIKELGGLYINFNADKLQPHKKTLSQIKEKKKNELLQKAVITPDFEKNYCVPPYSESKHQLQKQRRKERQKTAGNGWFGMKAPELTDELKNDLKALKMRASMDPKRFYKKNDRDGFPKYFQVGTIVDNPADFYHSRIPKKQRKKTIVEELLADSEFRRFNRRKYSEIMAEKAANAEGKKFRKKKKFRN", "length": 761 }, "evidence": [ { "id": "RGD:6497192", "url": "https://alliancegenome.org/gene/RGD:6497192#orthology", "database": "AGR" }, { "id": "MGI:1923173", "url": "https://alliancegenome.org/gene/MGI:1923173#orthology", "database": "AGR" }, { "id": "HGNC:24013", "url": "https://alliancegenome.org/gene/HGNC:24013#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080513-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080513-5#orthology", "database": "AGR" }, { "id": "SGD:S000004041", "url": "https://alliancegenome.org/gene/SGD:S000004041#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12035-1", "protein_name": "rRNA-processing protein FCF2", "gene_name": "FCF2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDQSVEDLFGALRDASASLEVKNSAKEQVSLQQEDVLQIGNNDDEVEIESKFQEIETNLKKLPKLETGFDALANKKKKKNVLPSVETEDKRKPNKSDKNDNDWFTLPKPDDNMRREVQRDLLLIKHRAALDPKRHYKKQRWEVPERFAIGTIIEDKSEFYSSRMNRKERKSTILETLMGDEASNKYFKRKYNEIQEKSTSGRKAHYKKMKEMRKKRR", "length": 217 }, "evidence": [ { "id": "RGD:6497192", "url": "https://alliancegenome.org/gene/RGD:6497192#orthology", "database": "AGR" }, { "id": "MGI:1923173", "url": "https://alliancegenome.org/gene/MGI:1923173#orthology", "database": "AGR" }, { "id": "HGNC:24013", "url": "https://alliancegenome.org/gene/HGNC:24013#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080513-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080513-5#orthology", "database": "AGR" }, { "id": "SGD:S000004041", "url": "https://alliancegenome.org/gene/SGD:S000004041#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5QJE6-1", "protein_name": "Deoxynucleotidyltransferase terminal-interacting protein 2", "gene_name": "DNTTIP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVVTRSARAKASIQAASAESSGQKSFAANGIQAHPESSTGSDARTTAESQTTGKQSLIPRTPKARKRKSRTTGSLPKGTEPSTDGETSEAESNYSVSEHHDTILRVTRRRQILIACSPVSSVRKKPKVTPTKESYTEEIVSEAESHVSGISRIVLPTEKTTGARRSKAKSLTDPSQESHTEAISDAETSSSDISFSGIATRRTRSMQRKLKAQTEKKDSKIVPGNEKQIVGTPVNSEDSDTRQTSHLQARSLSEINKPNFYNNDFDDDFSHRSSENILTVHEQANVESLKETKQNCKDLDEDANGITDEGKEINEKSSQLKNLSELQDTSLQQLVSQRHSTPQNKNAVSVHSNLNSEAVMKSLTQTFATVEVGRWNNNKKSPIKASDLTKFGDCGGSDDEEESTVISVSEDMNSEGNVDFECDTKLYTSAPNTSQGKDNSVLLVLSSDESQQSENSENEEDTLCFVENSGQRESLSGDTGSLSCDNALFVIDTTPGMSADKNFYLEEEDKASEVAIEEEKEEEEDEKSEEDSSDHDENEDEFSDEEDFLNSTKAKLLKLTSSSIDPGLSIKQLGGLYINFNADKLQSNKRTLTQIKEKKKNELLQKAVITPDFEKNHCVPPYSESKYQLQKKRRKERQKTAGDGWFGMKAPEMTNELKNDLKALKMRASMDPKRFYKKNDRDGFPKYFQIGTIVDNPADFYHSRIPKKQRKRTIVEELLADSEFRRYNRRKYSEIMAEKAANAAGKKFRKKKKFRN", "length": 756 }, "evidence": [ { "id": "RGD:6497192", "url": "https://alliancegenome.org/gene/RGD:6497192#orthology", "database": "AGR" }, { "id": "MGI:1923173", "url": "https://alliancegenome.org/gene/MGI:1923173#orthology", "database": "AGR" }, { "id": "HGNC:24013", "url": "https://alliancegenome.org/gene/HGNC:24013#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080513-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080513-5#orthology", "database": "AGR" }, { "id": "SGD:S000004041", "url": "https://alliancegenome.org/gene/SGD:S000004041#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R2M2-1", "protein_name": "Deoxynucleotidyltransferase terminal-interacting protein 2", "gene_name": "Dnttip2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVVTRSGLSRTRLQESSQQKRSAPRRIGTHLESTKESGSDGSTAESQPAEKQHSRSSSRTTGPAEIIVLISDDEASETESHTSGVTSVLEDQEPIVRVTRKRQIVIASTSKSTVRKRQKVAPQHASADEVVVSEAESHVSGVSMVVPSTERSSRNKANSQRDSSQESQSGTVSDAELSCSGISSLEILPRTTARNVKKKLQFPAEKNDTKITPGNKKQIVGMSVCSEDSDATQLSARPLSQRNMPNVSDSETYNSDFDDSSPRNSGKKLTAQNHQNLHIQEEKRANVVSLTEVRKENCKSLDEEDLKITEEKVINEKDSQRSLSEAQDTSLQQSVSQNHSSTPNKKPTFQLSSPDRKALMKSLEHKFAVVNVERWNDKRGGSGKKSDLAQLGGGGGGGDDNEPTGAGISDDKSSQSGVPLECDTKPCKSELSMTQDTTDSPVLLFLSSDESQQSDSSENERDTLCSVENNGQKEASAEDLEDAACDSALFVIDKTPGLSADKNFYLEDKAPSEVAIEEEKEEEEKEEENSEEDSSDSDENKDESSDEEDLLSNTKSKLLKLTSSSIDPGLNIKQLGGLYINFNVDKLQPHKETLTQIKEKKKNELLQKAVITPDFEKKHCVPPYSESKHRLQKQRRKERQKTAGNGWFGMKAPELTDELKNDLRALKMRAGMDPKRFYKKNDRDGFPKYFQVGTIVDNPADFYHSRIPKKQRKKTIVEELLADSEFRRFNRRKYSEIMAEKAANAEGKKFKKKKKFRN", "length": 758 }, "evidence": [ { "id": "RGD:6497192", "url": "https://alliancegenome.org/gene/RGD:6497192#orthology", "database": "AGR" }, { "id": "MGI:1923173", "url": "https://alliancegenome.org/gene/MGI:1923173#orthology", "database": "AGR" }, { "id": "HGNC:24013", "url": "https://alliancegenome.org/gene/HGNC:24013#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080513-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080513-5#orthology", "database": "AGR" }, { "id": "SGD:S000004041", "url": "https://alliancegenome.org/gene/SGD:S000004041#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZA2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "A0A8N7UZA2", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0A8N7UZA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UZA2" }, { "id": "PF08698", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08698" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fcf2 pre-rRNA processing C-terminal", "eco_id": "ECO_0000259", "start_pos": 817, "end_pos": 910, "start_aa": "Glu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 29, 109 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 16, "end_pos": 18 }, { "start_pos": 44, "end_pos": 46 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A0T301-1", "uniprot_ac": "A0T301", "uniprot_id": "A0T301_DANRE", "mass": { "chemical_mass": 96548.0, "monoisotopic_mass": 96548.0 }, "refseq": { "ac": "NP_001077346", "name": "olfactory receptor CQ19 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077346" }, "gene_names": [ { "name": "olfcq19", "type": "recommended", "evidence": [ { "id": "A0T301", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0T301" } ] }, { "name": "olfcq19", "type": "synonym", "evidence": [ { "id": "NP_001077346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077346" } ] }, { "name": "si:dkey-10i19.2", "type": "synonym", "evidence": [ { "id": "NP_001077346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077346" }, { "id": "A0T301", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0T301" } ] } ], "protein_names": [ { "name": "C-family odorant receptor OLFCQ19", "type": "synonym", "evidence": [ { "id": "NP_001077346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077346" } ] }, { "name": "Dr16-17", "type": "synonym", "evidence": [ { "id": "NP_001077346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077346" } ] }, { "name": "H21", "type": "synonym", "evidence": [ { "id": "NP_001077346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077346" } ] }, { "name": "Olfactory receptor CQ19 precursor", "type": "synonym", "evidence": [ { "id": "A0T301", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0T301/entry#names_and_taxonomy" } ] }, { "name": "olfactory receptor CQ19 precursor", "type": "synonym", "evidence": [ { "id": "NP_001077346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077346" } ] }, { "name": "sub 16_16", "type": "synonym", "evidence": [ { "id": "NP_001077346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077346" } ] }, { "name": "v2rh21", "type": "synonym", "evidence": [ { "id": "NP_001077346", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077346" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMN18715719 [ECO:0000350] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EF089137.1. On Apr 5, 2007 this sequence version replaced XP_001343344.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001077346", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077346" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A0T301", "url": "https://www.uniprot.org/uniprotkb/A0T301" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "olfcq19", "url": "https://www.uniprot.org/uniprotkb/A0T301", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd06364", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06364", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd15283", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd15283", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100003908", "url": "https://www.ncbi.nlm.nih.gov/gene/100003908", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000068", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000068", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011500", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011500", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017978", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017978", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR028082", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028082", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038550", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038550", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100003908", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003908", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HEIHTFR", "url": "https://omabrowser.org/oma/group/HEIHTFR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0T301", "url": "https://www.orthodb.org/?gene=A0T301", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24061:SF418", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24061:SF418", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00003", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00003", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01094", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01094", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07562", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07562", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001077346", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001077346", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58HS83", "url": "https://www.uniprot.org/uniprotkb/A0AC58HS83", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HS83-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HS83-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0T301", "url": "https://www.uniprot.org/uniprotkb/A0T301", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0T301-1", "url": "https://www.uniprot.org/uniprotkb/A0T301-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-283", "url": "https://zfin.org/ZDB-GENE-070705-283", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MWVILNISIYLIFNFIMSASILGSNTCQLQGHFRLNEMYHDGDVILGGLFEVDFLTVFPDLDFKTEPEPPYCVQFDMESFQQAQTMAFAIDEINKNPNLLPNITLGYHLFDNCVMLGMAFRAAISMASGTEEFFNNINCTGPPPVIGIVGDSSSTVSIAISSILGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKYFRWTWVGLIYSDDDYGVYAAQSFQQEMQLFGGCVAFSEVLPHDNNLEDIKHITKMIQASTARVIVVFSTPSFLIPLIDELVLQNMTDRQWIASEAWATSFVHHSPRLLPFLKGTLGIAIRRGEIQGLYEFLLRLQPTNDPKNNMIRIFWEIMFGCNFETGGKKNSGDQVINICTGQEDLRTTKTPYTEVSELRASYNVYKAVYALAHALNDLMQCEDGRGPFSVNSCADITNLKPWQLVHYLQNVNFTTDFGDHVSFDKNGDALAIYDVLNWQPSSDGSIRAQTVGVVNEEVATGMVLTLDEDALYWNFESKKPPSSVCSESCAPGTRLATIKGLPVCCFDCLPCGDGEISNITGAVECTMCPDEFWSNLDKDQCIPKEVEFLSYEDPLGISLTTASLLGTCFCVLVMFVFAVHRNTPIVRANNSELSFLLLLSLKMCFLCALLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPESKGAMKWFGAVQQRCTVLVLTAIQVVICAVWLSTASPAPHKNNQYIRSKIVYECAIGSVAGFSMLLAYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIILLHPERNTKKAIMGKEAQNT", "length": 868, "header": "tr|A0T301-1|A0T301_DANRE Isoform 1 of Olfactory receptor CQ19 precursor OS=Danio rerio OX=7955 GN=olfcq19 PE=3 SV=1 CANONICAL=A0T301-1" }, "isoforms": [ { "isoform_ac": "A0AC58HS83-1", "url": "https://www.uniprot.org/uniprotkb/A0T301/entry#A0AC58HS83-1", "sequence": { "sequence": "MWVILNISIYLIFNFIMSASILGSNTCQLQGHFRLNEMYHDGDVILGGLFEVDFLTVFPDLDFKTEPEPPYCVQFDMESFQQAQTMAFAIDEINKNPNLLPNITLGYHLFDNCVMLGMAFRAAISMASGTEEFFNNINCTGPPPVIGIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKYFRWTWVGLIYSDDDYGVYAAQSFQQEMQLFGGCVAFSEVLPHDNNLEDIKHITKMIQASTARVIVVFSTPSFLIPLIDELVLQNMTDRQWIASEAWATSFVHHSPRLLPFLKGTLGIAIRRGEIQGLYEFLLRLQPTNDPKNNMIRIFWEIMFGCNFETGGKKNSGDQVINICTGQEDLRTTKTPYTEVSELRASYNVYKAVYALAHALNDLMQCEDGRGPFSVNSCADITNLKPWQLVHYLQNVNFTTDFGDHVSFDKNGDALAIYDVLNWQPSSDGSIRAQTVGVVNEEVATGMVLTLDEDALYWNFESKKPPSSVCSESCAPGTRLATIKGLPVCCFDCLPCGDGEISNITGAVECTMCPDEFWSNLDKDQCIPKEVEFLSYEDPLGISLTTASLLGTCFCVLVMFVFAVHRNTPIVRANNSELSFLLLLSLKMCFLCALLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPESKGAMKWFGAVQQRCTVLVLTAIQVVICAVWLSTASPAPHKNNQYIRSKIVYECAIGSVAGFSMLLAYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIILLHPERNTKKAIMGKEAQNT", "length": 845, "header": "tr|A0AC58HS83-1|A0AC58HS83_DANRE Computationally mapped isoform of Olfactory receptor CQ19 isoform X1 OS=Danio rerio OX=7955 GN=olfcq19 PE=3 SV=1 CANONICAL=A0T301-1" }, "locus": {} }, { "isoform_ac": "A0T301-1", "url": "https://www.uniprot.org/uniprotkb/A0T301/entry#A0T301-1", "sequence": { "sequence": "MWVILNISIYLIFNFIMSASILGSNTCQLQGHFRLNEMYHDGDVILGGLFEVDFLTVFPDLDFKTEPEPPYCVQFDMESFQQAQTMAFAIDEINKNPNLLPNITLGYHLFDNCVMLGMAFRAAISMASGTEEFFNNINCTGPPPVIGIVGDSSSTVSIAISSILGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKYFRWTWVGLIYSDDDYGVYAAQSFQQEMQLFGGCVAFSEVLPHDNNLEDIKHITKMIQASTARVIVVFSTPSFLIPLIDELVLQNMTDRQWIASEAWATSFVHHSPRLLPFLKGTLGIAIRRGEIQGLYEFLLRLQPTNDPKNNMIRIFWEIMFGCNFETGGKKNSGDQVINICTGQEDLRTTKTPYTEVSELRASYNVYKAVYALAHALNDLMQCEDGRGPFSVNSCADITNLKPWQLVHYLQNVNFTTDFGDHVSFDKNGDALAIYDVLNWQPSSDGSIRAQTVGVVNEEVATGMVLTLDEDALYWNFESKKPPSSVCSESCAPGTRLATIKGLPVCCFDCLPCGDGEISNITGAVECTMCPDEFWSNLDKDQCIPKEVEFLSYEDPLGISLTTASLLGTCFCVLVMFVFAVHRNTPIVRANNSELSFLLLLSLKMCFLCALLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPESKGAMKWFGAVQQRCTVLVLTAIQVVICAVWLSTASPAPHKNNQYIRSKIVYECAIGSVAGFSMLLAYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIILLHPERNTKKAIMGKEAQNT", "length": 868, "header": "tr|A0T301-1|A0T301_DANRE Isoform 1 of Olfactory receptor CQ19 precursor OS=Danio rerio OX=7955 GN=olfcq19 PE=3 SV=1 CANONICAL=A0T301-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Evolution of vomeronasal-type odorant receptor genes in the zebrafish genome.", "journal": "Gene", "date": "2005", "authors": "Hashiguchi Yasuyuki, Nishida Mutsumi", "evidence": [ { "database": "UniProtKB", "id": "A0T301", "url": "https://www.uniprot.org/uniprotkb/A0T301" } ], "reference": [ { "type": "PubMed", "id": "16226854", "url": "https://glygen.org/publication/PubMed/16226854" } ] }, { "title": "Evolution and origin of vomeronasal-type odorant receptor gene repertoire in fishes.", "journal": "BMC Evol. Biol.", "date": "2006", "authors": "Hashiguchi Yasuyuki, Nishida Mutsumi", "evidence": [ { "database": "UniProtKB", "id": "A0T301", "url": "https://www.uniprot.org/uniprotkb/A0T301" } ], "reference": [ { "type": "PubMed", "id": "17014738", "url": "https://glygen.org/publication/PubMed/17014738" } ] }, { "title": "The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids.", "journal": "BMC Genomics", "date": "2006", "authors": "Alioto Tyler S, Ngai John", "evidence": [ { "database": "UniProtKB", "id": "A0T301", "url": "https://www.uniprot.org/uniprotkb/A0T301" } ], "reference": [ { "type": "PubMed", "id": "17156446", "url": "https://glygen.org/publication/PubMed/17156446" } ] }, { "title": "Molecular and neuronal homology between the olfactory systems of zebrafish and mouse.", "journal": "Sci. Rep.", "date": "2015", "authors": "Saraiva Luis R, Ahuja Gaurav, Ivandic Ivan, Syed Adnan S, Marioni John C, Korsching Sigrun I, Logan Darren W", "evidence": [ { "database": "UniProtKB", "id": "A0T301", "url": "https://www.uniprot.org/uniprotkb/A0T301" } ], "reference": [ { "type": "PubMed", "id": "26108469", "url": "https://glygen.org/publication/PubMed/26108469" } ] }, { "title": "Overlapping but distinct topology for zebrafish V2R-like olfactory receptors reminiscent of odorant receptor spatial expression zones.", "journal": "BMC Genomics", "date": "2018", "authors": "Ahuja Gaurav, Reichel Vera, Kowatschew Daniel, Syed Adnan S, Kotagiri Aswani Kumar, Oka Yuichiro, Weth Franco, Korsching Sigrun I", "evidence": [ { "database": "UniProtKB", "id": "A0T301", "url": "https://www.uniprot.org/uniprotkb/A0T301" } ], "reference": [ { "type": "PubMed", "id": "29792162", "url": "https://glygen.org/publication/PubMed/29792162" } ] }, { "title": "Expansion of vomeronasal receptor genes (OlfC) in the evolution of fright reaction in Ostariophysan fishes.", "journal": "Commun. Biol.", "date": "2019", "authors": "Yang Liandong, Jiang Haifeng, Wang Ying, Lei Yi, Chen Juan, Sun Ning, Lv Wenqi, Wang Cheng, Near Thomas J, He Shunping", "evidence": [ { "database": "UniProtKB", "id": "A0T301", "url": "https://www.uniprot.org/uniprotkb/A0T301" } ], "reference": [ { "type": "PubMed", "id": "31263779", "url": "https://glygen.org/publication/PubMed/31263779" } ] } ], "pathway": [ { "id": "dre:100003908", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003908", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KAL5-1", "protein_name": "Vomeronasal 2 receptor 19 like 1", "gene_name": "Vom2r19l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFTMIFLFLLLNIPLLMVDFIHPRCFWRMKQNEDKDGNPGTGCTFFLQSVHWPVEKEYYSDIFNIQMHNENHKYALALAFAIYEINGNPDLLPNMSLIFEFTRDVCDWESQLNSVIQSSLKNHNILPNYICKEFTKCPMALTGLNWTTTLKLHTILNNFISQQFLQVTYGPFHPVLSDNEKFPYLYQMASDDKSLALALVSFIIHFGWNWVGLAISNNDQGIQFLSYLRREMEKGTVCFAFVNMIPVNMHLYMSRAEMYYNQIMTSSTNVVILYGDTDSTLAVSFRMWESLGIEKIWVTNSWWAATLSKKDHTFDNLYGTYAFGQHHGEISGFKNFVQTLNPAKYSDEHLVKLEWMYFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFTGGSYDIYNAVYSFAHALHEMTFQIFDNLPKDNGREHNYSCKKLCSFLRKTSFTNPVGDRVNMNQRHKQKEEYDIFYIWNFPQGLGIKVKIGMFSPYFPNGQQLHLSEDVLEWAKGSAQMPTSACSADCGPGFRKSWKDGMATCCFHCKPCPENEISNETNVDVCARCPDDQYANIEQNRCIPKAVVFLSYEEPLGMALSLISLGFSVFTIVLLGVIVKHHNTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNSAICILQQITFGVVFTVSVSTVLAKTITVILAFKVTASQRMMKYFLVSRVPNYIIPTFTLFQVILCAVWLGASPPSIDIDAKSEHGHIIIACHKGSVTTFYCVLGYLGTLASGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGKIMVAVEIFSTLASSAGMLGCIFVPKCYTVLFRQDQNSLVMIRMKSSSHAHIS", "length": 857 }, "evidence": [ { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A0R4IS27-1", "protein_name": "Olfactory receptor CG6 precursor", "gene_name": "olfcg6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFLFYTILLFHLLHTKVENSLCRIMGDSNYPLFSKNGDVSIGGIFAIHRKETLPSFEFMQKPQPLSCSSVNLRDFRLAQTMIFAVEEINRSKSLLPNVSIGYKIYDTCGSRLSTMTAIMGLMNGQDFSTEDRCNGQSRLHAIIGESESSATIVLSRTTGPFRIPVISHSSSCECLSNKKDYPSFFRTISSDYHMSRALVYIVKHLDWSWVGAVNSDNDYGNNGMAIFLKAAHEEGICVEYSVKFYRTEPEKLKKVVDTINKGTAKVIVAFVSFVEMGLLIDQLSIQNITGIQMIGVEPWITANTYITSNSFRAMGGSLGFATKYIYIEGFAEYVMTPFWNTAFPCSESDRNHSHYELICSRYEDLLALKNDNKDVNEHRYSSNVYKAVYAVAHSLHGLLNCKEQEGCEKGLTIQPQQVVKALKNINFTIKSGDSVWFDNTGSVVALYEVVNWQKDSDGSFQFKSVGFYDAMMPPYKNLRLNTKNIVWAGGQLEKPRSVCSESCAPGTRKAAQKGRPVCCYDCIPCAEGEISNETDSINCKQCPGEYWSNTERNRCVIKAVEFLSFSEVMGIVLVIFSLFGAGLTVLVAVLFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTKWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPVQQRLSVFAFTLIQVLICVLWLTISPPFPYKNMKYYKEKIILECNLGNTIGFWAVLGYIGLLAALCFLLAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSFGLLVSIFAPKCFIILLKPEQNTKQHVMGKTTCSL", "length": 837 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A3B2W422-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r54", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSASMWGYRVTQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQKEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSYQSLGKIEETVQKMQKCTAKVVLVFLSNLNFQLILRGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVSSLNAEETVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFVLALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQICLSPGTSTFVVLIASLIQVVLCGVWLATSPPFPDKDMISEPQHIVIQCQEGSGATFFCVLGYLGFLAGGTFSVAFLARGLPDIFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLKQGYCAQQEKQGEMLQRRYKFSGESPEPNI", "length": 878 }, "evidence": [ { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W4A7-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r53", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCTLLSVLFGCLSGSALSGPRVWIIPRQSPRFDRPGDVIVGGSFSIFHFSDGTLSNFTAPPPVLKTSSASMWSYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTCSHAVTQLVIHFQWSWVIILAHDDDFGQQASSLATQMLTPAGVCIEYHLHVPSHQSFGKIEETVQKMQKCTARVVLVFLSNSNFQLILHGLLAVPVSGQVWVSMDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSRIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHNLRNVYFKTSDGNKIMFDANGDLVTQFDIFQGKKTPAGVFHLVHVGLIDPQASSGNKMMVQLKQDLQVSSLNAEITVPTSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFTDQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTIFAVVFTVAVSSVLAKTLTVVLAFRVTRPRSRIQVCLSSGASTSVVLIASLIQVVLCGIWLITSPPFPDRDMISEPRHTVIQCHEGSGANFFCVLGFLGFLAGGTFSVAFLARGLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHQVQHNRQCEMLQRRCVSSGESLGSSL", "length": 878 }, "evidence": [ { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2W842-1", "protein_name": "Vomeronasal 2, receptor 66", "gene_name": "Vmn2r66", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLISVFWFLKISSIFCHLSDPRCFWRIKDTKNHLGDKENNCFFSIYTKRGYVKNDYFSCNLDKQVTPKTIHLIFSVYLAIEEINKDYHILPNISLLVNIECDQRIYDKKSGLGLKSKEIIPNYYCRNQRRYLIVLTIPEWTVSTSLGPFLYISRIPELYCGNFHLLLNDNEQFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGAIVTNDDHGIQFLSELRGEMQKHIVCLSVAIIIQTEKIMALKEFHTHYNQIIMSSAKVVIVYGDKDSPIHFALIVWKSKGIWRIWVSVSQFDMITIIGDFLLYSSIGTFIFSHQQPEIPGFEQFIQTVHPSNYSSEHSLAKLWWTYFRCSLPPSNCKKLKNCPTTTVFKWLFMTPLGMAMSNTCYNLYNGVYAVALSLHEMILQQVDTWSMNAGKELEFDSWKLFYFLKTLQFVNPAGELVIMNQNLKQDTEYDIFFIMDFKKYYGLKIKIGRFSGHLPSGQQLLMSTEMIKWATGIDQILPSVCSMPCRPGLRKSPQEGKDICCFVCYPCPENEISNMTSNVIIYQNMDQCVKCPEDQYANEDQTLCLQKVVAVLDYRDPLGKALAGFALCFSVLTSVVICVFLKHRETPIVKANNQTLSYVLLISLIFCFMSSLLYIGHPTMVICILQQTTFAIVFTVAASTILAKTITVVLAFKATVPGRRMRWLLVSGAPKYIILICTMVQLILCGIWLRISPPFVDADIHMLHGQIIIVCNKGSVVAFYCVLGYMGSIALASFTVAFLARNLPHTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTTVAVEVFCILASSAGLLLCIFAPKCYLILLRPQTNSFYKFRRPHAKAENIS", "length": 858 }, "evidence": [ { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A3B2WBA1-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r56", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLSCHWLSDPLAGMWLCTLLPVLFGCPSGSALSGARAWLLPRQSPHFDRPGDVIVGGSFSIFRFSNGTLSNFTAPPAGLQTSSVSMWGYRVAQSFVFAIEEINRSTHLLPNLTLGFSIRNSGDSAHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFPQVSYSSSLPSLSDKIQFPSFIRTLTSDLTSSHAVTQLIIHFQWSWVIILAHDDDFGQQASSLASQVLTPAGVCIEFYLYVPSHQSLGKIEETVRKMQKCTARVVLVFLSNYNFQLILYGLLAVPVSGQVWVSKDTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCMWPYQNITVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHDMISYEHQDGKGTNSQDFQPWQLLHVLRKVHFKTPDGSEIMFDANGDLVTKFDIFQGQKTPDGVFHLVCVGLIDPQASSGNKMMVQKKMLKYQMKHAQVPTSVCSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCCIILLKPEKNTSSWLRQGHHV", "length": 865 }, "evidence": [ { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I6GK53-1", "protein_name": "Vomeronasal 2 receptor, 33", "gene_name": "Vom2r33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLCTFLFVLLGCLPGSALSEPRSWILPRQSPHFDRPGDVMVGGSFSIFCFSDGTLSNFTAPPTGLQASRVSMWGYRVAQSFVFAIEEINKSTQLLPNLTLGFSIQNSGDSVHGALYETMGFLTGQEEPIPNYTCCHGSPQAALVGDTRSSLSLPMARLLGLYKFSQISYSSSLPSLSDKIQFPSFLRTLPSDLTSCHAVTQLIIRFQWSWLIILSQDDDFGEQASSLATQQLSAAGVCIEFHLDVPSQHSLGKIEETVQKMQKCTARVVLVFLSNSNFQLILSGLLAASVSGQVWVSNDTLHIAMALSIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLHPSQIPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQVCSGNESLKNKPYPFPEVSKIDAAYTAVYSIAHALHDMVACEHQDGIDTNPQDFHPWQLLHVLKKVHFRTPDGSEIMFDANGDLVTKFDILQGQKTLNGVFHLVHVGMIDPQASSGNIMMIQLKEDLQVSSMNAEITVPTSICSERCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALMAILLAGLALLVLGVFLKHRDTPVVRVNNRTLSYFLLISLSLCSLCSLLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTVTVVLAFRVTKSGSRIQVCLSPGASTSVVLIASLIQVVLCGVWLATSPPFPERDMISEPQHIVIQCQEGSGATFFCVLGFLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYHSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPAWLRQGHCAHQDRQCSLFH", "length": 864 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1N5X2-1", "protein_name": "Olfactory receptor CW1 precursor", "gene_name": "olfcw1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKTPVLRAIHLVFFLFYPIQSNSEANCKLWKELDLTVVHKEGDVILAGMFPIHSKGIDQELNFRNQPDQRKCWGFNMRVFRWSQAMIFFIEEINRNPTLLPNITLGYRLYDTCGLIALSLRTALSVVSQPMKRSSSEMCSSPSIPIIIGDSGSTLSMAISRLLNLFHIPLVSYFASCACLSNKHQFPYFFRTIPSDVNQANALARLVKHFGWTWVGTVGADDAYGRTGIDLFTAAVTQLGVCVSYRIIIPKLPTQQQLQDIVRTIRDSSAHVLVAFAIEEDIKPVVDEIVLQNVTGKQWVASEAWVTSTLISTKENFPSLSGTIGFAIRRAEIPGLKHFLDSIQPLADPYNVFAREFWETQFQCTLNTSLPTSSTMDPVNYSHSCTGMERMQDTQSIFNDVSQLRVTYNMYKAVYTVAHALHNLLLCQREHRSALTQQCPDIHNLQPWQVIEVLRKVNYTNMFGDLIYFDENGDPVGSYDIVNWQKGGDDVPVQYITVGRFDSSLPKGQQLVLNQNKIVWHGGTNKVPVSVCSASCPPGYRKVRLEGQPVCCYDCMLCAEGSISNTTDQAECLLCPEDFWSNKHRNYCVPKEIEFLSYLEAFGMVLAAIAILGAVAAISVGVVFFRHRDTPLVRANNSELSFLLLISLTLCFICALTFLGQPSHWACPLRRISFGLTFALCLSCLLSKTLVVLIAFKSTLPGNNTARWFRPPQQRLGVFICSLLQGGVCIAWLTTASPYPVKNTWLYRDRIILECHLGSVVYFCCVLGYIGCLAAFCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSYGVLLCIFAPKCYIIIFMPEKNSKKYLMTQK", "length": 866 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PS22-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcx1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQIYATLLTLCLLLYIRVQCQSNNKYKCIYQGDDDTYSFYQGGDLVLGGIFPLHSSTIPQFFSFTTKPKLIQYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPEKGSGQSCEDTRKQPSPVIVGEASSGVSMAVLRTLGTFQIPLVSYFASCSCLSNKREFPAFMRTMPSDLFQIKALVKLVYYFKWTWLGVIGVDTDYARFAIQLFLKESEKYNICPAYVHIYPVALTQNTVEELVKILKSSSARVILNFSVDSYLYGVLKECRRQNVTNLQWIASEAWATSKVLWDDFGDLLKGTLGFAIRRADIPHLGSYLRSVSSSVAQTSPFFTEFWEETFHCRLNGSLNTHVHEEASYNWPACNGNETLDDVYTLYSDVSQLRVSYNVYKAVYLIAHALHDMSTCDPGKGPFKNGTCGSLYQILPWQLLYYMKRTNFTTLGEEVRFDKNGDPIASYDLMNWQRESDGSLQLVRVGIYDASFKDDKDLVIDESVIMWHRGDKAPESLCSKSCLPGSRKARQKGKPVCCFDCISCAEGEISNQTDSIDCLTCSKDTWPNQSQDQCIPKTLEFLSFQEPLGIILWVFSALGACAALAVLCVFVMYRTTPVIRGNNIELSFLLLLFLCACFLIGLTFLGKPTDWLCQIRYPAFGISFTLCISCILAKTVVVLMAFRATIPGNNVMKWFGPVKQRSSVILCTCVQALICIIWLTTKPPLASYNSKFLSATIIVECSVGSEVGFWCVLGYIGFLSSLCFFLAFLARKLPDNFNEAKFITFSMLIFFAVWITFIPVYVSSSGKYMVAVHVFAILASAFGLLMCIFAPKCYVVLLKPERNDKKSMMKK", "length": 866 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1PU52-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWISLNIFLYLSLNCIFAASVVNPGTCQLQGHFKLNGMYQDGDFILGGLFEVHFFTLFPKLSFKSEPEPPYCEKFDMESFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCVMLGMAFRAAISLASGTEEYFSNLNCTGPPPVIGVVGDPGSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVRILSHFGWTWVGLIYSDDDYGIYASVSFQQEMQQFGSCISFSEILPHDNNPKDIQRIMEVIKASTASVVVVFSTSSYLMPLIDEVVLQNLTGRQWIASEAWATSPVFHTPRYLPFLGGTLGIAIRRGEILGLQEFLLHIHASNNPKDNMLKIFWENMFRCSFETRSKDTIGEQEKSICTGHEDLSTTKTPYTDVSGLRASYNVYKAVYALAHALHDLMECEEGRGPFDGNSCGNITNLKPWQLVHYLQKVNFKTGFGDHVSFDENGDALAIYDVLNWHPSSDGSIRLHTVGVVNEGAGTGKVLSLDESALYWNFQTKNPPRSVCSASCPPGTRQAMRKGLPICCFDCLPCGDGEISNATDSTECVTCPDEFWSNFDKNQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHLNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHVVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGTMKWFGAAQQRCTVLVLTALQVVICAVWLSNASPTPIKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKKAIIRRETKKR", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" }, { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q146-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq18", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYQDGDFILGGLFEVHFFTVFPDLTFTTNPKSPYCEIFNMEGFQHAQTMAFAIEEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLTSGTEESFLNLNCSGPSPVIGIVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSNRKKYPSFFRTIPSDAFQVRAIVQVLKHFKWTWVGLLYSDDDYGVYAAQSFQQEMRQFGLCAAFSEFLPHDNNPRTIQHIMGVIQGSTAKAVVVFAPSSFLIPLMNEVVLQNMTGRQWIASEAWATSLESHIPSFQPFLRGTIGIAIRRGEIQRLHDFLLRIRPSNDPKNYMLRIFWENMFGCSFGKGDTEGEQVIKVCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHALHDLMECEEGKGPFSKNSCADKTNLKPWQVVHYLQNVNFTTGFGDYVSFDKNGDALAIYDVLNWQPSSDESIRIYTVGVVKEGTETGMVLTLDEDAIFWNFETRKPPRSVCSESCPPGTRRATRKGLPVCCFDCLPCGDGEISNTTNAVECFLCPDEFWSNQYNNHCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVIFVFALHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHVVFGISFVLCMSSILVKTMVVIAVFKSSRPEGKGAIKWFGAVQQRSTVVVLTVLQVLICAVWLSTASPTPYKNNQYIRSKIVYECAIGSVVGFSMLLSYIGFLAAASFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFVPAYVSSPGKYTVAVEIFAILASTFGLLIAIFAPKCYIILLHPERNTKNVIMGRETQNK", "length": 829 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q166-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq13", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWSPLIICLYLSYNFKSAASILMGSCQLQGHFGLNGMYQAGDVILGGLFEVHLLAVFPELSFRSAPEPPYCEQFDMASFQQAQTMVFAIDEINKNPKLLPNITLGYHLYDNCVMLGMAFRAAISLVSGTEELFSNLNCTGSPPVIGIVGDSNSTPSIAISSVLGLFRVPIVSYFATCSCLSNRKQYPSFFRTIPSDAFQVRAMVNILKHFGWTWVGLIYSDDDYGNYAAQSFLQDIQIYGGCVAFTEILPLNNNRKYIEHVVGVIQASTARVVVVFSTSTYVLPLMDEVVLQNVTNRQWIASEAWATSPMFHTQRLLPFLGGTLGIAIRRGEIQGLHEFLLHLRPKNDQHNNMVRIFWEKMFGCRFNPGGKGDKQCSGQEDLSSIDTAYTDVKELRASYNVYKTVYALAHALHDLTECDEERGPFSENRCADITNLQPWQLVHYLQKVNFTTGFGDHVSFDKNGDVLAIYDVMNWHPSSDGSISVRTVGVVNEGAASGKVLTLDEDAIYWNFKIKKAPQSVCSESCPPGTRQATKKGLPVCCFDCLPCGDGEISNVTNAIECTVCPDEFWSNKDKDQCVPKEVEFLSYEDPLGISLTTACLLGTCFCALVMIIFCQHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGSMKWFGTTQQRCTVLILTALQVVICIVWLSNSSPAPHKNSQHISSKIVYECAIGSLAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVTSPGKYAVAVEIFAILASSFGLLGAIFAPKCYIILLHPEKNTKKAIMGRQITK", "length": 860 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1Q1C5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNAHLLFTVKMLCIARLCIAVCGVDLGTCILQGDAQPPALSEDGDFIVGGAFTIHYYVRTEKYTYTRRPQPLECSGSMDFRELRFARALQFAIQEINNSSDLLPGIFLGYHIYDSCGSVPMAIKVALQLANGLDPKYNDTDSCAKSAAVLALVGDSASTPAISISRIFGPFEIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEKEGICVEYSEAYYRTYPLSKLKRVADVIRRSTARVIVAFVAAGDMRFLLEELSKEPLPPMQWIGSEAWVSDPQMLRFNLSIGTMGVAVPRSLIPGFRKFLLDLSPYKVLKFPLLTEFWESSFSCSLQQQTDPSTGMPACDGTEDLGRLKNPYTDTSQLRVSNMVYKATYAIAHALHGIVCNETQCSKNIKVKPRQVFDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPEGQEFSLNKAIIWYDGSEKVPVSVCSENCPPGTRKAVKKGRPVCCYDCIPCGEGEISNKTDSPDCDKCPPDYWPSTEKDKCLPKPVEFLSWDEILGIILAVLSVSGSLLALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWVVLGYIGLLASLCFVLAFLARKLPDNFNEAKFITFSMLIFSAVWITFIPAYVSSPGKFTVAVEIFAILASSFSLILCIFAPKFFIILFRPEENTKKHLMGKVQSKSY", "length": 856 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RHU5-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCCYICVTLIASTGTCQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMTSFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTSRQWIASEAWVTAAVFRTPYFQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTTNTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEGSIKLHNIGVVNEVATGMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTSRAMRKGFPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDRCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AUZ8-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcv3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHSLETMTILLLWLLVYHLSVLNPAQASKCLLQNEFEPGLMANGDFVIGGIFPLHYNQEMPDLNFTYKPGPVKCNGFDTRAFRWAITMKLAVEEINKRVDLLPNYTLGYKIFDSCAYPLTGQRSAVAVLNGPNELESPLCADAAPLLAVIGESGSAQSIVVSRILQPFGIPMISYFSSCACLSDRREFPTFFRVIPSDAYQVKAIAKLLRHFNWTWIGVIRGDHEYGRFALQGLLKELEGTGICVAYQKMIPLLYDRQKALEIIHVMSHSTARVVVVFSAEGELTPFLRDYMEQNVTGIQWIASEAWVTSSVFAGSEFDPFLGGTIGFGIRQGQIPRLKEYLTTVNPERYPTNPLVYELWGALYGCSPSWSNLSSHLPSCTGKETVRLQYSAYLNTSSPRISYNVYKAAYAIAYSLHNLIYCTPGKGPFSNSTCANAPHIYPWQLQQYLQEVSFTISGEKVNFDMKGDSIPSYDLINWQRGSAGNIEFINVGMFDGALESGQELVIKEEAIMWPGHQTEVLVSVCSNSCAPGFRKAVRRGQPLCCFDCVPCDSGKISNETDSLDCIACSEDYWSNADGTVCIPKVVEFLSHDAMGLTLTVIAVAGACLTLAVFSVFLYYKNTPVVRINNSELSFFILLSLTLCFLCALIFIGEPTSWSCMLRHTAFSITFSLCISCILGKTLVVLAAFTATRPGNNLMKWLGPTQQRIIIFCCTLIQVLICTVWLVASPPFPYRNTKYQQSKIILDCSVGSDLAFWCVLGYIGLLACVCFFLAFLARKLPGNFNEAKYITFSMIIFCAVWLAFVPAYVSSPGKFTTAVEIFAILASSFGLLLCLFTPKVYIILVKPEKNTKQHLMGKDK", "length": 859 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3AV03-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfck3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYNNVLLIVTLQCIITRLYVVYGNRLGSCILQGDPQPPVLFDEGDFIIGGAFSIHYYLRTEKHTYTMRPQSLECSGSMDFRELRFARVLQFAIQEINNSSDLLPGITLGYRIYDSCGSVPMAVKLSFQLANGLDLIFNDNDSCSKSAAVAALVGESGSTPSISISRLYGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEEEGICVEYSEAYYRTQPRSKLMRVADVIRRSTARVIVAFMASGDMRLLLEELSQQPLPPMQWIGSEAWFTDPEMLRFNMCIGGVGFAIPRSVIPGFRTFLLDLSPQRAMKFPLLTEFWESSFSCSLKQQTGPSTGMPACDGTEDLGRLKNPYTDTSQLRISNMVYKATYAIAHALHGIICNEKKCNKNIKIEPREVLDKLKQVKFSKNNYSVSFDAYGDPVAVYELVNWQLQKDGSIDFVTVGKYDSSQPKGKEFSLSRAIIWYDGTEEVPVSVCSESCPPGTRKAVQKGRPVCCYDCINCADGEISNDTDCLDCHECLSDYWPNNEKNKCLRKPVEFLSWDEILGIILAAFSVAGSLVALSMALVFYKNRASPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPSQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFGLILCIFAPKFFIIIFRPERNTKKHIMGKVPSKAL", "length": 856 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B2Z8-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcg8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLFLYSVLSLYHLNTKAENTLCQMIGNPKYPLLSKDGDITIGALFVIHSEVSLPSFAFTQKPNLLSCSSLNIKDFRLAQTMIFAIEEINKNTNLLPNISVGYQIYDTCGSRFHSMSATMALMNGPKNSEGYTCNEQSSVHAIVGETESSNTIILSRTTGPFKIPVISPTATCECLSNRKEFPSFFRTIASDYHQSRALAYIVKHFGWTWVGAVNSDNDYGNNGMATFQKTAKEVQICVEYSVKFIRTETEKIRNVVNVIKKGTAKVIVAFLTGFEMKSLLEQLSSQNITGLQMIGVEAWITSKTLITSKSFHVLGGSLGFAVRKIQIEGFADYVMKAFWDTAFQSFSNADLNYSQYQDLLLVKNYNEDVLEQRFVSYVYKAVYALAHSLHSLLRCTEQGGCGKALTIQPHQLVEALRKVNFTVKMGDQVWFDSTGGVIAQYDVVNWQQNSDGSVQFQSVGYYDASLSPDQRFMLNTEKIVWAGGQLEKPRSVCSESCPPGTRKASQKGRPVCCHDCIPCADGEISNETDSNNCKQCPGEYWSNANKNKCVTKAVEFLSFTEVMGIILVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSIPFIGRPTQWSCMLRHTAFGITFVLCISCILGKTIVVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTLIQGLICVIWLTKSPPFPYKNMKYFQEQIILECSVGSTIGFWAVLGYIGLLAVLCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKLTVAVEIFAILASSFGLLFCIFAPKCYIILLQPEQNTKQQMMAKTPSKI", "length": 832 }, "evidence": [ { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PAH3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcd1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTKKSELLLLMVLVTHGICVPNLAQVCRLLGQPALPLLSEERNINIGAIFSLHKSALLKSHNFTSKPKQTTCGGLNLREFKFVQTLIFAIEEINNSSLLPGASLGYKIYDSCGSVAQAIFSGMALMNGYEETLSDTSCSTPPAVHAIVGESNSSPTIGLASVVGPFSLPLVSHFATCSCLSNRKRFRTFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGIATFEEAAKQEGICIEYSEAVFKTDPEVQFLKTIEVIKKATTKVVVAFMAFGDFVLLLKVMAQQNITGIQWIGSESWITSRNLAETKEYHFLSGAVGFAIANSKPVGLREFLMNVHPDKELNNELLKEFWETVFLCSFRNSSSGGCTGSEKLSELQNEYTDFSELRIENKVYTAVYAVAHSLHNVLKGFKFFTNSSKKQLPTPQKVLEYLRDVNFTVNTNENIFFDASGDPVARYDLVNWQPTKDGSLQFKLVGIYDSSLPSEQRLQINQESMLWAGNSGQLPVSVCSESCPPGTRKAVQKGRPICCYDCIPCAEGEISNYTDSSDCFPCGLEYWSNESKDRCVLKVIEFLSYTEIMGVGLCIFSFIGVLLTATVSFLFYFYKETPIVRANNSELSFLLLFSLTLCFLCSLTFIGRPTDWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLIQVIICVLWLTMSPPFPFLNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFFARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSAPGKYTVAVQLFAILASSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKS", "length": 849 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PD42-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq20", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWITLCIYLYLSLNYICAHSILRTSDSCRLQRRFHLNGMYKDGDVILGGLFQVHFFTVFPEQSFRTEPEPPFCEKFDMESFQQAQTMAFAIEEINKNPNLLPNITLGFHLYDNCVRLGMAFRAAISLASGTEESFQNLNCTGPPPVIGIVGDPSSTPSIAISSLLGLFRVPIVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLIYSDDDYGVYAAQSFHLEMQMFGHCVAFSEILPHNNNQRDIQRIMGVIQASTARVVVVFSTSSFLLPLIDEVASQNMTGRQWIASEAWATSPVYHSPRLLPFLGGTLGIAVRHGEIPGLHDFLLHLGPGNESRNNMLRIFWENMFGCSFEPGVKDTNSEIKLCTGQEDLSTTNTPYTDVSGLRAAYNVYKAVYALAHGLHDLMQCEKGRGPFRGESCADITNLKPWQLVHYLQKVNFTTGFGDHVSFDENGDALAIYDVLNWQPSSDGSIQIFTVGVVKERTETGMVLTIDEDAIYWNFETKKSPQSVCSESCSPGTRRATRKGLPVCCFDCLPCRDGEISNTTDAIECMLCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGSCFCVLVMIIFGLHRNTPIVRANNSELSFMLLLSLKMCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKGAMKWFGAAQQRCTVLVLTVLQVVICSVWLSTASPTPYKNNQYIRSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYIILLHPERNTKNAIMGRETQKR", "length": 867 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PFV7-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcg9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLLYLCTLLLFFKLKVSVGNASCKIMGEPKYPLLFKDGDVTIGALFPVHSIETAPSFEFTQKPQLLSCSSVNLRDFRLAQILIFAIEEINRSESLLPKLSLGYKIYDTCSSKLSSMSATMALMNSFEFAGRDKCNGQTSVHAIIGETESSATVILTRTTGPFKIPVISHAASCECLSSRKEYPSFFRTISSDYHQGRALAYIVKHLGWSWVGAVNSDNDYGNYGMAIFLNTAHKEGICVEYSEKFYRTEPEKLKKVVDTIKKSTAKVIVAFISFLEMRLLVEQLSAENITGLQIVGVEGWTTSKSLITPKTLNVLRGSLGFAMRKIYIEGFAEYVLKPFWDTAFPCIPNQRNDSWVILNCSRYQDLLVLKNYIEDVPEHRFSINVYNAVYAVAHALHSLFKCKEQEGCEKDLLTQPQQVVDALKKVNFTVKMGDRVWFDSTGATLAQYEVVNWQQNSDGSVNFKKVGYYDASLPPDQRFVLNIKEILWAGGNLKKPRSVCSESCPPGTRKAAQKGRPICCYDCIPCADGEISNDTDSNNCKQCQGEYWSNADKNKCVQKSVEFLSFTEVMGIVLVFFSLFGAGLTVLVAILFYSKKDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGQPTQWSCMLRHTAFGITFVLCISCVLGKTLLVLMAFKATLPGSNIMKWFGPVQQRLSVLAFTFIQVLICVLWLSISPPFPHKNMKYYEEKIILECSLGSTIGFWAILGYIGLLAALCFILAFLARTLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILSSSISLLLCIFAPKCYIILLKPEQNTKQYMLGKTTSKFY", "length": 839 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PPM0-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcg12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVFFCTLLIFFQLYAKAEKPICIMMGDPKYPLLSKEGDISIGAVFPVHSIETLPLFKFTQKPQLLSCSSVSIRDFRMAQIMAFAIEEINRNESLLPNVSLGYQIYDTCGSGLSLMGANMALMNVQEFASRGSCNGQSPVHAIIGETESSNTVILSRTTGPFKIPVISPSASCECLSNRKEYPYFFRTIASDYHQSRALAYIIKYFGWSWVGAVNSDNDYGNHGMAIFLSTAEKEGVCVEYSVKFQRTEPEKLKKVVDTIKKGTSKVIVAFLTEFEMKNLLEYLIIQNVTGLQVIGVEAWITANSMIKPNSFHVLGGSLGFAVKKLNIEGFEDYVTKAFWETAFPCSQTSQKENSQYKLICNIYRDLLVLKNDNKDVPEQRYASNVYKAVYAVAHSLHNILKCRENGACETDMKIQPQQVVEALRKVNFTIKMGDCVWFDSTGAVVAQYEVVNWQPDYNGSIQFKPVGYYDASLPPNQRFVINTENIIWAGGQLKKPRSVCSENCPPGTRKAVQKGRPVCCYDCIPCAEGEISNETDSNNCKQCPGEYWSNAEKNKCVLKAVEFLSFKELMGIVLVFFSLLGAGLTTLVAILFYSKKDTPIVKANNSELSFLLLFSLMLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSDVMKWFGPIQQRLSVLVITIVQVLICVLWLAVSPPLPYKNTKYFKEKIILECSLGSTIGFSAALGYIGLLAILCFILAFLARTLPDKFNEAKFITFSMIIFCAVWITFIPSYLSSPGKLTVAVEIFAILASSFGLLFCIFLPKCYIIMCKPEQNTKLHIIGKLNK", "length": 837 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2U8-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLCEMWITLNICLYMYFNHISGVFTSESCQLQGCFKLNGMYQDGEFIIGGLFEVQNLKVFPELSFTNEPELPQCEEFYMASFQQALTMVFAINEINSNSKLLPNITLGYQIYDNCLRLGVAFRAAMSLVSGTEESSNLSCTGPPPVIGIVGDPGSTQSITISSVLGLYRVPMVSYYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILRHFGWTWVGLLYSNDDYGIYAAQSFQQEMQILGGCVAFSEMLPYDNNGRDIQRIAGVIQKSTAKVVVAFSTDLASLMDELLLQNVTGKQWIASEAWTTTPVLQTPQYLPLLGGTLGIAIRRGQIQGLYEFLKNLRPDKNPKNSTIRIFWETMFGCKFEVGGKKVDEQQERGRNKCSGQEDLNNSETAYTDVSELRASYNVYKAVYALAHALHDLVKCEEGKGPFTGNSCADISNLKPWQLVHYIQNVKFTTGFGDHVSFDENGDALAIYDVMNWHPRSDGSIIVHVVGVYEEAILGKVLTLDEDALFWNFETKKPPDSVCSESCPPGTRRARKKGLPVCCFDCLPCGDGEISNTTDSPECFICPEDFWSSPENDRCVPKEMEFLSYDDPLGISLTTASLLGTCFCVLVLVIFAYHHNTPVVRANNSELSFLLLVSLKFCFLCVLLFIGRPRLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKTSRPEGKTSIKWFGSAQQRGTVIALTSAQVAICTVWLSSASPTPHKNNQYIHSKIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFMARKLPDNFNEAKFITFSMLIFCAVWIAFVPAYASSPGKYAVAVEIFAILASSFGLLAAIFAPKCYIIILHPERNTKKAIMGRSTQNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q2V5-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcx2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MALLCATLLMVWFLMYLSVQSQYNSKVRCVFQGDDDTNTFYQGGDVVLGGLFPLHFSPISSLSSYKTKPTPTTYKFFTPRALRWMQTMIFAVREINQRQDLLPNLSLGYHIRDSGDDIPVSVKRSLLLVNGQPDKDSGQSCEDTRKQPSPVVVGEASSGISMAVLRSLGCFKIPLVSYFASCSCLSNKKEFPAFMRTMPSDLFQIKALAKLVHYFQWTWVGVIGVDTDYARFAIQLFLKESQQLNICLAYVQLYPVALNQDSAEELVRMLKSSSATVIISFSVDSYLYGILKECRRQNVTHLQWIASEAWATSKSLWEEFGDLLKGTLGFAIHRADIPHLGSYLKEIRPQTSHFLSEFWEETFRCRLNGSLNTHAHGEQAQNWPACNGSESLDDVYTTYSDVSQLRVSYNVYKAVYLIAHALHDMSTCVPGKGPFQNGTCGSLFQIQPWQLLYYMKQTNFTTLGEEIRFDENGDPIASYDLMNWQRGSDSSLQLVRVGFYDASLEDDKDLVIDESLIMWHRAEKAPESLCSKSCLPGSRKARQKGKPVCCFDCISCAEGEISNHTDSIECLTCSEDTWPNQSQDQCIPKTLEFLSFQEPLGIILWVFSAFGACAALAVLCVFVMYRKTPVVRGNNIELSFLLLLFLCACFLIGLTFLGKPTDWLCQIRYPAFGISFTLCISCILAKTVVVLMAFRATIPGNNVMKWFGPVKQRSSVILCTCVQALICIIWLTTKPPLASYNSKFMSETIIVECSVGSEIGFWCVLGYVGLLACLCFLMAFLARKLPDNFNEAKFITFSMLIFFAVWITFIPVYLSSSGKYMVAVHVFAILASAFGLLLCIFFPKCYIVLLKPEKNDKKHIMKK", "length": 863 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T5D2-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAVLLFCLVLSCYYICVTLMASTGICQQQGHFTINGMHQDGDFVIGGLFDVQTYLKVYPEISFRTQPKLPNCELFYMESFQQALTMVFAISEINHNPNLLPNITLGYQIYDTCLRLRVAFQAATALISGTEETISDFNCKGPPPVIGLIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAIVQTLRHFGWTWVGLIYSNNDYGIYAAQSFHQEMQLFGHCVAFSEILPQDNNPRVIDHIMGVIQASTARVVVVFSASSLLIPLMNKVVLHNLTSRQWIASEAWVTAAVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETGDKETFGQQMKKVCTGLEDLSTANTPYTDVSGLRATYNVYKAVYALAHALHDLMQCKEKRGPFSGNSCADITDLKPWQLVHYLKKVNFTTSFGDSVSFDNNGDALAIYDVLNWQPSSEESIKLHNIGVVNEVATEMVLTLNNDEIYWNFEAQKPPQSVCSESCLPGTRRAMRKGLPVCCFDCLICGDGEISNTTDAIKCTVCPDEFWSNLNKDQCVPKEIDFLSYEDPLGISLTTTSLLGTCFCALVMIIFTFHRNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGSGAMKWFGTAQQRCTVLVLTALQIVICAVWLSTSSPTPYKNNQSIRSKIVYECAIGSLAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWVAFVPAYMSSSGKYAVAMEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRENKNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6G6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X1", "gene_name": "olfcq9", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWAILLFCLFLSCNFICVTLMVSSGTCQKQGHFTLNGMHQDGDFVIGGLFEIQSYVKVYPEISFRTQPKLPNCDLFYMTSFQQALTMVFAISEINNNPNLLPNITLGYQIYDNCLRLGVAFRAATALISGTEETISDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRLPMISYYATCSCLSDKKKYPSFFRTIPSDTFQVRAMVQTMRHFGWTWVGLIYSNNDYGIYAAQSFHKEMQLFGHCVAFSEILPQDNNPRVIDHIIGVIQASTARVVVVFSASSLLIPLMNKVVLQNLTGRQWIASEAWVTSTVFRTPYYQPFLKGTLGIAIRRGEIQGLHSFLLRLHPNSDQRNNIVRIFWETMFGCSFETEDKETFGQQIKKVCTGQEDLSITNTPYTDVSGLRAPYNVYKAVYALAHALHDLMQCKEKRGPLSEKNCADITDLKPWQLLSYLKKVNFTTGFGDPVSFDNNGDALAIYDVLNWQPSSEGSIKLHSIGVVNDEVATGMVLRLNKDEIYWNFEAQKAPRSVCSESCPPGTRKAMRKGFPVCCFDCLTCGDGEISNTTDAIKCTVCPDEFWSNFNKDQCVPKEIEFLSYEDPLGISLTTASLLGTCFCALVMIIFAFHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGQPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFNSSRPEGKGAMQWFGAAQQRCTVLVLTVLQVVICAVWLSTSSPTPHKNNQYVRSKIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGVLVAIFAPKCYIIILHPERNTKKAIMGRETKKY", "length": 869 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7T6Z6-1", "protein_name": "Extracellular calcium-sensing receptor isoform X2", "gene_name": "olfcq17", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLYLSLCLCFKHIYADSIHRLRSCQLQGRFKLNGMYQDGDFILGGLFHVHFFTVFPELSFRMEPQQPYCEKFNMEGLQHAQTMAFAINEINKNPTLLPNITLGYHLYDNCVMLRMAFRAAMSLASGTEDSYSNLNCTGPPPVIGIVGDASSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMVQILKHFKWTWVGLLYSGDDYGVYAAQMFHKEMQLSGHCVAFSEILPNDHNPKDIQRIIRVIQGSTARVVVVFALSSFLIPLMDEVVLQNMTGCQWIASEAWATSLEYHTPRFLPFLGGTLGIAIRRGEIEGLHEFLLRIRPSNDTSQNIVRIFWENLFGCRFETGGLKTGREQEKMECTGQEDLSTTNTPYTDVSGLRASYNVYKAVYALAHGLHDLMQCEEGRGPFIGNSCADITSLKPWQLVHYLQNVNFTTGFGDHVTFDKNGDALAIYDVLNWQPSSDGSITVHKIGVVYEGATTGMMLTLDADAIYWNFETKKPPLSVCSESCPPGTRQATRKGLPLCCFDCLPCGDGEFSNTRDAVECMMCPDEFWSSPDKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVMIIFALHHNTPIVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKGAMKWFGASQQRCTVLVLTALQVVICAVWLSTASPTPHKNNHYFRSIIVYECAIGSVAGFSLLLGYIGLLAAISFLLAFLARNLPDNFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFALLLAIFAPKCYIILLHPERNTKNAIMGRETQNK", "length": 868 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7TDV0-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfck1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRISLGWVVCLVKEMHVNLLLILTLLCIRRLFPAVCGVHLGTCILQGDPQPPSLFSKGDFVIGGTFTIHYYLRTEKRTYTVRPQPLMCSGSMDFRELRFARVLQFAIQEINNSSNLLPGITLGYHIYDSCASVPMVIKVAVQLANGLQLAFNDTDSCAQSSEVLALVGESGSTAAITTSRLFGPFGIPQVSHYATCACLSDKRQHPTFFRTIPSDHHQAAALARMVKRFGWTWIGAVRSDSDYGNNGMASFLKAAEVEGICVEYSEAYYRTQTRNKLQRVADVIRRSTARVIVAFMAAGDMRFLLEELSQQPPPPMQWIGSEAWVTDPQMLRFNLSIGAVGFAIPRSVIPGFRKFLLDLSSEQALKIPVLKEFWESSFGCSLKQHTGYFSGMPACDGTEDLGTLKNPYTDTSQLRISNMVYKATYAIAHALHGIVCNGKLCDKNIKVEPRKVSDQLKQVNFSKNNYSVSFDANGDPVAVYELVNWQLQGDGSIDFVTVGKYDASQPKGQEFSLNRAIIWYDGTEKVPVSVCSESCPPGTRKAVKKGRPVCCYDCINCADGEINNETDSLDCHKCQPDYWPNAEKIKCLPKPVEFLSWDEILGNTLAAFSIAGSLVALSMALVFYKNRVSPIVRANNSELSFLLLFSLTLCFLCSLTFIGQPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMAFKATLPGSNVMKWFGPPQQRLSVFGFTLVQIIICVLWLTISPPFPYKNMQHYKDKIILECSLGSAVGFWAVLGYIGLLAFLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKFTVAVEIFAILASSFSLILLIFAPKCFVIVFRPEENTKRHLLGKVPPKAL", "length": 870 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UUY1-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MWVILHIYFFISCNYMSVALMASSGTCQLQGHFTLNGMYQNGDFLIGGLFEIQYLKAFPGLSFRTEPKLPHCENFYMTSFQQAITMVFAINEINNNPNLLPNITLGYQMYDNCLRLGVAFRAATALISGTEETLSDLNCKGPPPVIGVIGDPGSTHSIAISSVLGLFRMPMISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMIQILRHFEWTWVGLLYSDDDYGINAALSFHHDVQQFGGCVAFSEILPNDNNQMAVQHIVRVIQNSTAKVVVVFSTSSYLLPVIDEMLLKNITGRQWIASEAWSTSPVLLNPRLRYVLGGTLGIAIRRGEIEGLDNFLLRLRPDNFSQNSMMRIFWENMFECNFDTIGGLRTKLCSGQEDLRSKFTPYTDVSELRASYNVYKAVYALAHALHDLMHCEEGRGPFSENRCVDISNLKPWQLVHYLQRVKFTTGFGDHVSFDKNGDALAIYDVLNWQLSSEESVTVRRIGVVDEGVTTGKVFTLDENAIYWNFETNKPPRSVCSESCPPGTRQATRKGLPVCCFDCLPCGDGEISNTTDTTECIACPNDFWSNPEKDQCIPKEVEFLSYEDPLGISLTTAAMLGTFICALVMTIFAHYRNTPVVRSNNSELSFLLLLSLKLSFLCVLLFIGQPQLWTCQLRHAVFGISFVLCVSSILVKTMVVIAVFKSSRPEGKNAMKWFGAAQQRGTVLILTALQVLICAVWLSTASPTPHKNSRYIRSIIVYECAIGSVAGFSLLLGYIGLLAAVSFLLAFLARNLPDSFNEAKFITFSMLIFCAVWIAFVPAYVSSPGKYAVAVEIFAILASSFGLLLAIFAPKCYIIILHPERNTKKAIMGKGTKNK", "length": 863 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8N7UVL1-1", "protein_name": "Extracellular calcium-sensing receptor-like", "gene_name": "olfcq12", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLTWHRLFIKATPSKVFIINNIHRGELKRNVEMWIIAKICLYLSFSCISVASIFRSGPCQLQGQFRLNGMFQEGDLILGGLFEVHFLTVFPEQSFRTEPEPPYCEQFDMASFQQAQTMVFAIDEINRNPNLLPNITLGYYLYDNCVKLSVAFRAAMALVSGTEESFSSLNCTGPPPVIAIVGDPGSTHSIAISSILGLFRVPMVSYFATCSCLSDRKTYPSFFRTIPSDAFQVRAMVQILKRFGWTWVGLLYSDDDYGIYAAQSFQKEMQLFGACVGFSEMLPRDNNHEDIQSIVEVIQTSTARVVVVFSTEAYLLPLMDEVALKNVTGRQWIASEAWATSPVFHTQHLLPFLGGTLGIAIRRGEIQGLKEFLYYLHPDSNTRNNIVRIFWENIFGCSFEIGGRERKVCTGQEDLKSTNTAYTDVSGLRASYNAYKAVYALAHALHDLMQCEDGRGPFSGNKCADQINLQPWQVVHYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWQPSSDGAISVSTVGVVNEGASMKMVLTLKENSIFWNFKNRKPPQSVCSESCPPGTRQVRRKGLPVCCFDCLPCADGEISNTTDAIECKICPDELWPNPNKDQCVPKEEDFLSFEDPLGISLTTASLLGTCFCALVMVIFSHHRNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPKLWTCQLRHAAFGISFVLCVSSILVKTMVVIAVFKSSRPESKSAMKWFGVAQQRGTVMALTTLQIVICTVWLSMASPKPYKNSLYISSKVVYECDIGSVVGFSLLLGYIGLLAAVSFLFAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYAVAVEIFAILASSFGLLVAIFAPKCYMILFHPERNTKKSIMGRATQIK", "length": 894 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "MGI:3588220", "url": "https://alliancegenome.org/gene/MGI:3588220#orthology", "database": "AGR" }, { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" }, { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V5L1A2-1", "protein_name": "Parathyroid cell calcium-sensing receptor", "gene_name": "Vmn2r55", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLCAFIFAFFVCLSGSDLSGPRAWILPRQSPHFDRPGDVIVGGSFSIFHFSDGTPSDFTAPPTGLQTSSVSMWGYRVAQSFVFAIEEINRSAHLLPNLTLGFSIRNSGDSVHGALYETMGFLTGQEEPIPNYTCQHGSPQAALVGDTRSSLSVSMARLLGLYKFSQVSYSSSLPSLSDKIQFPSFLRTLTSDITSSHAVTQLIIHFQWSWVIILAQDDDFGQQASSLATQQLSPAGVCIEYHLHVPSHQSLGKIEETVQKMQKCTSKVVLVFLSNSNFQLILHGLLGVPVSGQVWVSKGTLHMALALTIPGISQVLQGTFGLLYHSSRAIGFPEFLAHLRPSQTPEDMFIKKFWEFTFDCTWPYQNSTVTEGVQFCTGNESLKNKPHPFPEVSKIDAAYTAVYSIAHALHNMLACEHQERKGTNSHNFHSWQLLHALKKVHFKTLDGIKIMFDANGDLVTKFDIFQGQKTPAGVFHLVHVGMIDPQVSSGNKMMVQLKEDLQVPSSICSESCLPGFSQVPRLGAPHCCFDCSPCPEGQFADQRDMKRCLLCPKEQYSSHTRDHCLPRTEIFLAFEEPLGFILALVALLLAGLAVLVLGVFLKHRDTPVVRANNRTLSYFLLISLSLCALCALLFLGRPTVTTCLLRQTTFAVVFTVAVSSVLAKTLTVVLAFKVTRPRSRIQICLSPGTSTLVVLIASLIQVVLCGVWLATFPPFPDKDMLSEPQHIVIQCHDGSGATFFCVLGYLGFLAGGTFSVAFLARDLPDVFNETKFLTFSMLLFCSVWTAFLPLYYSARGKSTVAVEIFSILASTAGLLGGIFIPKCYIILLKPEKNTPSWLKQGHHI", "length": 845 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0AB13A3P1-1", "protein_name": "Olfactory receptor CG7", "gene_name": "olfcg7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSANSLFMVSLTFRMILYFYTILFLRCFQAKTENAFCQIIGEAKYPLLSKDGDVTIGGIFAIHSKETLPSFEFQQKPQPLLCSSVNLRDFRLAQIMIFAIEEINKSENLLPNVSIGYRIFDTCGSRLSSMSATMGLMNELKFAAGETCNGQSPIHAIIGETESSATVILSRTTGPFKIPVISHSASCECLSNRNDYPSFFRTISSDYHQGRALAYIVKYLGWSWVGAVNSDNDYGNYGMAIFLETAQKEGICVEYSVKFYRTETEKLKRVVDTIKKSTAKVIVAFVSFIEMGLLIEQLSIQNITGFQIIGVEGWITSKNYITTNSFHSMGGSLGLALRKIHLEGFLDYVTKSFWSTAFPCSQTEGILPTVGCSKYKDLLPLKNYTEDVPEHRYSSHVYKAIYAVAHSLHSLLKCKEGEDCEKGHATQPQQVVEALKKVNFTVKFGDRVWFDRTGATVAHYEVVNWQQDTDGSFQFKQVGYYDASLPPDQRFVLNIESIIWPGGNLEKPRSVCSESCSPGTRKAAQKGRPVCCYDCVPCADGEISNETDSVNCKQCPREYWSNGEKNKCVLKAIEFLSFTEIMGIVLVCFSLFGVGLTAVVAILFWSKMDTPIVKANNSELSFLLLFSLTLCFLCSLTFIGRPTEWSCMLRHTAFGITFVLCISCVLGKTIVVLMVFKATLPGSNVMKWFGPTQQRLSVLAFTFIQVLICVLWLTISPPFPNKNMTYYKEKIIIECSLGSTISFWAVLGYIGLLAVLCFILAFLARKLPDNFNEAKFITFSMLIFCAVWITFIPAYVSSPGKFTVAVEIFAILASSFGLLLCIFAPKCYIIICKPEQNTKQHVMGKTSLKVQ", "length": 851 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TCB3-1", "protein_name": "Extracellular calcium-sensing receptor", "gene_name": "olfcq6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNFGAGLRTGSRNGNEKWKRMTFCRSSAFCHMFSSTLYLISSMARHAVVLRAGACQLQGRFRLNGMYQDGDVILGGLFEAHFFTLFPELTFRTEPAPPYCEIFNMESFQYAQTMAFAINEINRNPSLLPNISLGYHLYDNCVMLGMALRAAMSLVSGIEESFLNLNCTGPPPIIGVVGDPSSTPSIAISSVLGLFRVPIVSHYATCSCLSDRKKYPSFFRTIPSDAFQVRAMIQLISHFGWTWIGLLYSDDDYGTYAAQSFHQEMQLFGFCIAFSEPLRYDSNPRDIQRLMEVIQASTSTVVVVFSPSTLVIPLMNEVVLQNMTGRQWIASESWATSPVFYTPRFLPFLGGTLGIAIRRGEIEGLREFLLQLRPKNDPRNNMLKIFWENMFGCSFETGPHVKNVCTGQEDLSTTNTPYTDVSELRAANNVYKAVYALAHALHDLMKCEEGKGPFSKNSCAEISNLKPWQLVHYLQKVNFSTRFGDHVSFNKNGDALAIYDVMNWQPGSDRSIRIHTVGVVSEELEKGLMLTLDEDAIYWNFETKKPPQSVCSESCPRGSRRATRKGHPVCCFDCLPCRDGEISNTTDATKCTVCPDDFWSNLYKDQCIPKEVEFLSYNDPLGISLTTASLLGTCFCAFVMVIFVHHHNTPIVRANNSELSFLLLFSLKLCFLCVLLFIGRPQLWTCQLRHAVFGISFVLCISSILVKTMVVIAVFKSSRPEGKMAMKWFGAAQQRCTILALTAIQVVICVVWLSTASPTPHKNNLYIRSIIVYECTIGSVTGFSMLLGYIGLLAAVSFLIAFLARNLPDNFNEAKFITFSMLIFCAVWITFVPAYVSSPGKYSVAVEIFAILASSFGLLVSIFAPKCYIILLHPERNNKKAIMGRETH", "length": 888 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0T300-1", "protein_name": "Olfactory receptor CD2 precursor", "gene_name": "olfcd2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MANTLSLLLLLLLLHGHFLPATVQICDLVGQSALPVLSAERDINIGAIFSIHRNALLRLYPFTSKPEPTTCVRLNLREFKFAQTFIFAIEEINNNTQLLPGVTLGYKIYDACNAISPTLVSGMALINGYENTLSDTSCSQPPAVQAIVGESSSSPTTALAALVGPFNIPVISHFATCACLSNRKRYPSFFRTIPSDYYQSRALAQLVKHFGWTWVGTVRSRSDYGNNGITAFEDAAKQEGICIEYSEAILRTDPQEQFRKTVEVIKKGTSKVVVAFISFGDFAPLVKVIAENNITGLQWVGSESWITSRNLAETKEYSFLSGAVGFAIVNAKLVGLKEFLVNVHPDQEPKNKLLKEFWETAFQCSFSNSDSALCTGSEKLGELKNEYTDVSELRIEHKAYAAVYAVAHTLHNVFKDVKAPNNSKRELPTPQKVLQYMRNLSFTIKTGENIFFDASGDPVARYDLVNWQTAEDGSLQFKHVGIYDSSLPSKQRLQVNQEIMLWAGKSGLLPLSVCTESCLPGTRKAVQKGRPVCCYDCIPCAEGEISNSTDSSDCFSCDLEYWSNEKKDRCILKVVEFLSYAEIMGIILCIVSFIGLLLTVMVTCLFYLHKETPIVRANNSELSFLLLFSLSLCFLCSLTFIGRPTQWSCMLRHTAFGITFILCISCVLGKTIVVLMAFRATLPGSNVMKWFGPLQQRLSVVSLTLVQVIVCLLWLTLSPPYPYMNLSYYREKIILECNLGSAFGFWAVLGYTGLLSTLCFVLAFLARKLPDNFNEAKFITFSMLIFCAVWLTFIPAYVSSPGKYTVAVEIFAILVSSFGLLFCIFAPKCYIILLKPEKNTKKQMMGKL", "length": 848 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3Z4N8-1", "protein_name": "Vomeronasal 2, receptor 72", "gene_name": "Vmn2r72", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKISFIFCHLSDPKCFWRIKDTENKIGDIETYCSFSISTKPGYVKNDYFILEIIFSTSVFRVTPKTNHLIFSVYLALEEINMNFHILPNISLVVNVECLRQKYDEKTGLALQSKEFIPNYSCTNERRYLIIFTAPIWAVTTRLGPLMFMYSIPELYCGHFHLSLSDNEQFPHLYQISPKDTSLPLAMVSLMVHFKWNWIGAMITNDDHGIQFLSKLRGEMQKHMVCLSFVFAILTEHSMVRKEFHKNFNLIVRSSAKVVIVYGDYASPIDLVLHWFKSKGLFRIWVSVSQFDIITNLGDFMLYSSSGTFIFSHQKPEISGFQKFIKTVYPSNYSSEFSFAKLWWTYFRCSLPPSNCKTLKNCPTKTVFKWLFRTPLGMAMSDTCYNSYNAIHAVAHSLHEMLLQQVDTWSNNDGKDLEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTEYDIFYIMDFQKHYGFKMKIGRFSGHLPSRQQLYMSKEMMEWATDVDQILPSACNIPCKPGFRKSPEEEMDICCFVCNPCPENEISNMTNMDQCVKCREDQYANEDHTLFLQKVVSILDYREPLGKALAGFALCFSVLTSGIFCVFLKHRETPIVKANNQTLSYVLLISLIFCFICSLLYIGHPTTVICILQQTTFAIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLVSGAPKYIILICTMIQLILCGIWLGTSPPYVDADVHMVHGHIIIVCNKGSVIAFYCVLGYMGSFALTSFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYQSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYIILLRPHINSFRNFRKPHAKTENIS", "length": 856 }, "evidence": [ { "id": "MGI:3647591", "url": "https://alliancegenome.org/gene/MGI:3647591#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z6L3-1", "protein_name": "Vomeronasal 2, receptor 49", "gene_name": "Vmn2r49", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFIFMGVFFLLNITLLMANFIDSRCFWRINLDEITDEYLELSCAFILAAVQTPIEKDYFNKTLNFLKTTKNHKYALALVFAMDEINRYPDLLPNMSLIIRYSLGHCDGKTVTPTPYLFHRKKQSPIPNYFCNEESMCSFLLSGPNWDESLSFWKYLDSFLSPRILQLSYGSFSSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYLKWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDEVSFPQKTEIYYKQIVKSLTNVIIIYGETYNFIDLIFRMWEPPILQRIWITTKQLNFPTSKTDISHDTFYGSLTFLPHHGEISGFKNFVQTWFHLRNTDLYLVMPEWKYINSEDSASNCKILKNSSSDASFDWLMEEKLDMAFSDNSHNIYNAVHAIAHALHEMNLQQADNQAIDNGKGASSHCLKVNSFLRRTYFTNPLGDKVFMKQRVIMQDEYDIVHFANLSEHLGIKMKLGKFSPYLPHGRHSHLYVDMIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNETNMDQCVNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMFCFLCSFFFIGLPNKVICVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRYFLVSGTLNYIIPICSLLQCELCAIWLAVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTLAFLAKNLPDAFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGMLGCIFVPKIYIILMRPERNSTQKIREKSYF", "length": 852 }, "evidence": [ { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z7M3-1", "protein_name": "Vomeronasal 2, receptor 73", "gene_name": "Vmn2r73", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLIFIFWFLKISYIFCHLSNPRCFWRIKDTKDKLGDKETYCFFSISAKHGYIRNDYFSWNLDKHVTPKTNHLIFSVYLALEEINKNSHILPNISLVVNIECVLLKYGEKTGLGLKHEEFIPNYYCANERRYLIVLTAPIWAVSTKLGPFLFMSRIPELYCGHFHLPLSDNEQFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGVIITNDNHGIQFLSELRGETQKQIVCLSVVIIIQTDDITAYKEYHMNYNKIVMSSAKVVIVYGDHNSPIKFVLFLWKSQGIFRIWVSVSQFDMITPLGDFMLYSASGTLIFSHQQSELSGFEKFIKTVKPSNYSSEFSFAKLWWTYFRCSSLPPSNCKKLKNCPTKTVFRWLFMTPLGMAMSDTCYNLYNAIYAVAHSLHEMLLQQVDTWSENAGKELEFDSWKMFSILKTMQFVNPAGDLVNMNQNLKQEREYDIFYIMDFQKDYGLKMKIGKFSGHLPSHQQLYMSKEMIEWATDMDQILPSICSMPCRPGLRKSPQEGKDICCFVCNPCPENEISNMTNMDQCVKCPEDQYANEDHTLCLQKIVAILDYRDPLGKALAGFALCFCVITSGVLCIFLKHRETPIVKANNQTLSYVLLISLIFCFICSLLYIGHPTIVICVLQQSTFAISFTVAASTILAKTITVVLAFKVTVPGRMRWLLVAGAPKYIILICTMIQLILCGVWLGTSPPFVDADLHMVHGHIIIVCNKGSVIAFYFVLGYMGSIALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWVTFIPVYYSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYNILLRPGKNSSHMFKKLHAKTENII", "length": 851 }, "evidence": [ { "id": "MGI:3646433", "url": "https://alliancegenome.org/gene/MGI:3646433#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZB66-1", "protein_name": "Vomeronasal 2 receptor, 26", "gene_name": "Vom2r26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFIFMVVFFLINIPLLMANVIDPRCFLRINLDEVKDGDLQSTCSFILEAVQIPMEKDYFNQTLNVLKTAKNHKYALTLAFSIDEINRNPDLLPNMSLIIKYSFGYCDGKTVTPTPYLFHEEFEKPIPNYFCKEETKCTFLLTGPHWGTSLLFLTKLDIFSSPRFLQLTYGPFHSTLNDNEQFPYLYQMAPKDTSLALAIVSFILYFNWNWVGLFISDEDQGNRFLSELKKVSESKKICFAFVSMISFSELLFHHKVEMYYDQIVMSSTSVIIIYGEGNSITELNFRIWESPVKHRIWVTTKQWNFPTSNRDLTHDTFYGTFTFQHHHGEISGFNNLVQTWYQLRSTDLCQVMPDWKYLNYEGSASNCEILENYTSGASLEWLLEQKFDMAFSDDSYNIYNAVYAMAHAFHELNLQQVDNQAIDNEKGASSHCLKLNSFLRKTHFTNPLGDKVIMKQREILQEDYDIFHTQYFSEHLGIKVKIGKVSQYFKRDQHFHLYVDMIELATGSKKMPSSVCTEDCGPGFRRIWKEGMAACCFVCKPCPENEISNDTNMDQCMNCPEYQFANTKHNKCIQKGVLFLSYEDPLGMALALIAFCFSAFTAVVLWVFVKHHDTPIVKANNRNLSYLLIISLMFCFLCTFFFIGHPNRATCILQQITFGIVFTVAVSTVLAKTATVVLAFKVTDPGRRLRNVLVSGTPNYIIPICSLFQCILCAIWLAVSPPFVDIDDYSEHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTVAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKIYIILMRPDRNILKFREKSYF", "length": 851 }, "evidence": [ { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZE87-1", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "Vom2r78", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFILMVVFFLLNLPLLMANFIDSWCFWRINLNESKKKDLEISCAFILGAVQLPMEKDYYNETLNVLKTTKTNKYALALAFTMEEINRNPDILPNMSLIIKHTLSYCDGKTALHIAKEKFFRPLPNYVCSEESMCSFLLIGLNWMSSIILFRDLDTFFFPRFLQISYGPFHSIFSDNEQFPYLYQMTPKDTSLALAMVSFILYFNWNWIGLIISDNDEGNQFLSELKKEAQNKEICFAFVNMMAIDDISFYDKTEMYYNQIVMSSTNVIIIYGETDSIIELSFRMWESPVIQRIWVTKSELDFPTSKRDLNHGTFYGTLTFLHHHGEISEFKNFVEMWDHLRSRNLNLLISEWKYFSYETSGSNCKILRNFTSNSSLEWLTEQKFQMAFNDESNSVYNAVYAMAHALHENNLQEIDKQEIRNGKGAGTHCLKLNSFLRKTHFTNPLGDRVIMKHRERVQEDYDIVHIHNFSQHLWIKVKIGKFSPYFPNGRLFHLYGDMIELATGSKKMPSSVCSADCSPGFRKTWKEGMAACCFVCSLCPENEISNETNMDQCVNCPEYQYANKEKSKCIQKGVIFLSYDDHLGMLLAIIAFCLSAFTAAILWVFVMHHNTPIVKANNRILSYILIMSLMFCFLCSFFFIGHPNRATCILQQITFGIVFTVSVSTVLAKTITVVLAFKITDPGRRLRNFLVLGLPNYIIPICSLLQCILCTIWLAVSPPFVDIDQHSEHGNIIIVCNKGSVMAFYCVLGYLACLAFGSFTMAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGRVMVAVEVFSILASSAGMLGCIFAPKLYIILMRPDRNYIQKIREKSF", "length": 848 }, "evidence": [ { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZEQ5-1", "protein_name": "Vomeronasal 2 receptor, pseudogene 67", "gene_name": "Vom2r-ps67", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAKIFFLIVVFLLLKLSFLFCHLSDPRCFWRIKDKENYQGDKDIDCFFSIYTEHGYVKNDYFSGNLDKQVTRKTIHLISSVYFAIEEINRNIHILPNISLLVKTECNLFADNVDTVRSLKKKEIIPNYYCKHQRRYLIVLTGPPWLTSYKLGPFLFFSRTPELYCGYFHFRADQEQFPHLYQMSPKDTSLPLAMVSLAVHFRWNWVGVIITDDDQGIQFLSELRTGVEKSTVCVAFVTITTDDRMLYFKMIHKYYHQIITSSAKVVIVYGDKESLIQYNFMLWKSKNVQRLWVSVSQFDMITMIGEFMLHSLHGSIIFSHQHSEMSGFKKFIQTVNPSNYSNDISFAKLWWTFFKCSLPPPNCTTLKNCPSKILSKWFFVSPLGMSMSDICYNLYNAVYAVAHSLHEMLLQHVEIYSDNDGKVVEFNSWKIFSLLKTIQFVNPAGDLVNMNQNIKLGTEYDIFYVMDFRKQEGLKMKIGRFSGHFPNDQQLFMSDEMIEWATDIKQTLVSICSVPCRPGLRKYFQEGKAVCCFDCYPCPENEISNMTDMDDCVKCPEDKYANTDKTNCLKKVVTFLDYEDPLGMTLAGLALWFSALTAIVLCVFLKHRDNPIVKANNETLSYVLLISLIFCFICSLLYIGHPSMARCILQQTTFAIVFSVAASTVLAKTITVVLAFKITLPGRRLRWLLLSGAPNYIIPICTMIQMILCGIWLGISPPFVDADLHMVHGHIIIVCNKGSVIAFYSVLGYMGSLALSSFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFLPVYHSTKGKAMVVVEVFCILTSSAGLLLCIFVPKCYIILLRPQINSFHNFSKMRAKATSIN", "length": 853 }, "evidence": [ { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZVB5-1", "protein_name": "G-protein coupled receptors family 3 profile domain-containing protein", "gene_name": "Vom2r28", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFILMEVFFFFLNIPLLMANFIDPKCFWRVNLNEVKDKDLSITCSFILEAVQMPTENDYFNQTLNILKTTKNHKYALALAFSIDEINRNPDLLPNMSLIIKYPLGLCDGQTTLPTPYLFNEIYFRPIPNYFCNEETMCTFLLTGPHWITSYSFWIHLNIFLSPSFLQLTYGPFHSTFSDNEQFPYLYQMNPKDTSLALAMVSFLLYFKWNWVGLVISDDDQGNQFLSELKKESKIKEICFAFVSMLAIDEISFYHKTEMYYNQIVMSSTNVIIIYGKTESIIELSFRMWESPVIQRIWVTTKEMNFPTSKRDLTHDTFYGTLTFLHSHGEISGFKNFVQTWYHLRITDLHLVMPEWKYFNYEASASNCKILKNYSSSASLEWLMEQTFDMVFSDGSRDIYNAVNAMAHALHEMNLHLVDNQAIDNGKGASSHCFKINSFLRKTHFTNPLGDRVIMKEREILQEDYNIFHTWNFSQHIGFKVKIGKFSPYFPHGRHFHLYVDMIELATGSRKMPSSVCTEDCSPGYRRFWKEGMAACCFVCSPCPENAISNETNMDQCVNCPEYQYANTKRDKCIQKNVMFLSYKDPLGMTLAFIAFFFSALTAVVLRVFVKHHDTPIVKANNRILSYLLITSLLFCFLCSFFFIGHPNRATCILQQITFGIVFTVAISTILAKTITVVLAFKVTNPGRRLRNFLVLGTLNYIIPICSLFQCILCAIWLAVSPPFVDTDEHTEYGHIIIVCNKGSVTAFYCVLGYLACLALASFTVAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKIMVAVEIFSILASSAGMLGCIFAPKIYIILMRPERNAIQKIREKSYF", "length": 853 }, "evidence": [ { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4AB78-1", "protein_name": "Vomeronasal 2 receptor, 43", "gene_name": "Vom2r43", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFSLILVLLFLKASLLFCTLNDPKCFLRIKDKKNVDGDKEVDCFFSIYAKHGHVKNDFFSGNLDKQLTTKNIHLILSLYFSIEEINSTPQVLPNISLLVKIECNLLADRSKISLSSRKGDYFPNFDCRNQRRYLIVFTGPMWFPTAMLGPLLYISRTPELYYGPFHPLLNTYEQFPYLYQMAIKDTSIAIGMVTLVIYFSWNWVGLMISDDDLGLQFASELREEMQRYDICLAFVTVITYNSKLFLTMAGMYYNQIIMSLAKVVIIYGDIDSFLQVIFRLWQFVDIRRIWIATSQWDIITSNGEFLFNSFHGTLSFSHHYSEISGFKEFIQTVYPLNYSNTISPAKLWWVNFNCFWPSSNCKKLKKCSRKMLLKWLSNNQFEMAMSETNYNLYNAVYAVAHSLHELILQQANTLSNNVEKELEFDSLQVLSSLKKIQFVNPAGDLVNLNQKENLNVDYDIFYTGDFLQSYGIKVKIGNFFKYLTQPQKLLMFDEMVDWATDIRQTLPSICSTPCNPGFRKSPQEGKAVCCFDCNPCPENEISNMTDMDYCYKCLDNQYANSEGTHCLSKTVIFLSYEDPIGVTLACLALCFSALTAVVFGIFLRNQDTLIVKANNRALSYCLLISLIYCFLCSLLFIGKPHMVTCIMQQTIFAVAFTVAVSTVLSKTITVVLAFKFTLPSKKMRWLMTSGTSVLIIPICTMIQLIICGIWLGTYPPYVDSDGHIEHGHILIVCNKGSVTAFYCVLGYLGSIALASFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWLTFLPVYHSTSGKALVIVEVFCILTSTAGLLICIFAPKCYIILLTPKNNSFHTFRHNANVK", "length": 847 }, "evidence": [ { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PVI0-1", "protein_name": "Vomeronasal 2, receptor 34", "gene_name": "Vmn2r34", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFIFMEVFFLLNITLLMANFIDPRCFWRINLDEIMDEYLGLSCAFILAAVQTPIENDYFNKTLNVLKTTKNHKYALALVFAMDEINRNPDLLPNMSLIIRYTLGRCDGKTVIPTPYLFRKKKESPIPNYFCNEETMCSYLLTGPHWEVSLGFWKHMNSFLSPRILQLTYGPFHSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYFSWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDDVSFPQNTEMYYNQIVMSSTNVIIIYGETYNFIDLIFRMWEPPILQRIWITTKQLNFPTRKTDISHGTFYGSLTFLPHHGVISGFKNFVQTWFHLRNTDLYLVMQDWKYFNYEDSASTCKILKNNSSNASFDWLMEQKFDMTFSENSHNIYNAVHAIAHALHEMNLQQADNQAIDNGKGASSHCLKVNSFLRRIYFTNPPGDKVFMKQRVIMQDEYDIVHFVNLSQHLGIKMKLGKFSPYLPHGRHSHLYVDRIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNETNMDQCVNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMSCFLCSFLFIGLPNRAICVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRNFLVSGTPNYIIPICSLLQCVLCAIWLAVSPPFVDIDEHTLHGHIIIVCNKGSVTAFYCILGYLACLALGNFSVAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGILGCIFVPKIYIILMRPERNSTQKIREKSYF", "length": 852 }, "evidence": [ { "id": "MGI:3757700", "url": "https://alliancegenome.org/gene/MGI:3757700#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9PW21-1", "protein_name": "Vomeronasal 2, receptor 74", "gene_name": "Vmn2r74", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFFLNSVFWLLKISFNFGHLSDPRCFWRIKDTENKLGDKETYCFFTISTKHGYVKNDYFRWNLDKKVTPKTRHLIFSVYLALEEINKNCHILPNISLVVNIECVLDKHDEKTDFLFKSEDLIPNYYCKNERRYLIVLTAPLWAVSSSIGPYLFMSRIPEVSQLYCGHFHLPLSDNEQYPHLHQISRKDTFLPLAMVSLVVHFRWNWIGVIVTNDDHGIQFLSEFRGEMQNKIVCLSFAIIIKTGKFLAVTELHMNYKQILMSSAKVVIVYGYRDSPIIYAFIVWKSQDLFRIWVSVSQLDMITFLGDFLLYASTGTFIFSHQKPEISGFEQFIQRIHPSNYSSEFSLAKQWWTYFRCSLPPSNCKKLKNCSTKTVFKWLFMTPLGLAMSDTCYNIYNAMYAVAHSLHGMLLQQVDTWSKNAGKELEFDSWKMFSILKTLKFVNPAGDLVNMNQNLKQDVEFDVFYIMDFQKDYGLKMKIGRFSEHLPSGQQIYMSKEMIEWATDIDQILPSICTMPCRPGLRKSPQEGKDICCFDCKPCSENEVSNMTNMDQCVKCPEDQYANEDHTVCLQKVVTILDYRDPLGKALAGFALCFSVLTSLVLVVFLKHRDTPIVKANNQTLSFVLLISLIFCFICSLLYIGHPTMAICILQQTTFAIVFTVATSTILSKTVIVILAFKITVPGRRMRWLLESGTPKYIIPICTIIQLILCGIWLGTSPPFVDADLHMVHGHILIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYIILLRPQKNYFYKFRKRRELNLTT", "length": 853 }, "evidence": [ { "id": "MGI:3643877", "url": "https://alliancegenome.org/gene/MGI:3643877#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q067-1", "protein_name": "Vomeronasal 2, receptor 79", "gene_name": "Vmn2r79", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLTFVFLVLKLSFLFCYLSDPRCFWRIKDRENYLGDKEADCFFSMYTKHGYVKNDYFSENLDKKVTLKTIHLISSVYFAAEEINRNSYILPNTSLIVKIECNLIADNVKRIWSLKKKEIIPNYYCKNQRRYLIVLTGPIWITSYILGPFLYFSQTPELYCGHFHLLLNDQEQFPHLYQMTPKDTSLPQGMVSLAVHFRWNWVGVIITDDDHGIQFLSELRAGMESNTVCLAFVTIITYNRKLYLKMYHKYYHQITMSSAKVVIVYGDKESPLQFNFILWKSENIQRLWVSVSQFDIITMIGEFMLNSVHGTLIFSHQQSEMSGFKQFMQTVHPSNYSNDISLAKLWWTYFKCSLPPPDCKTLKNCPTKTLLKRFFVPPLGMSMSETCYNLYNSVYAVAHSLHEMLLQQVDTCSENDGKVLEFNSWKMFSFLKTIQFVNPVGDLINMNQNRERDTEYDIFYIMDFLKHEGLKMKIGRFSGHFPNGQQLFISDEMIEWATDIKQTIASACSVPCRPGLRKYFQEGKAVCCFDCYPCPENEISNMTDMDQCLKCPEDEYANTDQTNCLKKVVTFLDYKEPLGMALTGLAVLFSSLTVVVLCVFLKHRDTPIVKANNETLSYVLLISLIFCFICSLLYIGYPSMVSCILQQTTFAMVFTVSASCVLAKTITVVLAFKITVPGRRLRWLLLSGAPNYIIPICTTIQMMLCGIWLGISPPFVDADLHMVHGHIIIVCNKGSVIAFYCVLGYMGSLALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFLPVYHSTKGKAMVAVEVFCILASSAGMLLCIFVPKCYLILWRPQINSFHEFRKMHVKNKNIN", "length": 851 }, "evidence": [ { "id": "MGI:3646882", "url": "https://alliancegenome.org/gene/MGI:3646882#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q281-1", "protein_name": "Vomeronasal 2, receptor 114", "gene_name": "Vmn2r114", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLLADFISPRCFWKMKQNENRDRNQGTGCTFMIHAVQRPVEKEYFSHILNIQTHAENYKNVLALAFSIYEINRNPDILPNMSVRFTISKYNCYWESELMSLIHLSLQNHDILPNYMCKELTRCTMALTRLNWVTTVKLNTILNNFISQQFFQITYGPFHPVLSDHEKFPYLYQMASDHTSLALALVSFIIHFSWNWVGLAISDNDQGIQFLSYLRRVMEKNAVCFAFVNMIPMSMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQIAFQKFDLPKDNGKEHNYSCKKLYSFLRKTQFTNPVGDRVNMNQRDKLQEEYDIFYIWNFPQGLELRVKIGMFSPYFPNGQQVHLSEDMIEWAKGSAQMPTSVCSAECGPGSRKFRMDGMAACSFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNHCIRKTVVFLSYEEPLGVALSLISLFFSAVTIVVLGVIVKHHSTPVVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGVVFTVSVSTVLAKTITVVLAFKITASQRMMKYFLVSGAINYIIPFCILIQVIVCAVWLGASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYHSTKGRVMVAVEIFSILASSAGMLGCIFVPKCYTILFRPDQNSLEMIRAKSSSRAHIS", "length": 856 }, "evidence": [ { "id": "MGI:3648252", "url": "https://alliancegenome.org/gene/MGI:3648252#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q3F5-1", "protein_name": "Vomeronasal 2, receptor 76", "gene_name": "Vmn2r76", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIDMFSFISVFLVLKASMLFCSLNEPKCFLRIKDKKNKDGDKEVDCFFSIYTKHGHMKNEHFSGNLDKQLTTKNIHLILSLYFAIEEINMSPHLLPNISLLVKVECKLLADGSKVSLSSRRGDYFPNYNCGNHRRYLIVLTGPMWLPTAMLGPLLYISRTPEVRRLYYGPFHPLLSSFEHFPYLYQIAIKDTSVAIGMVSLVIYFGWNWVGLMISDDGLGLQFASELREEMQRYDICLAFVTIITYNTKLFLTMTDTYYNQIMMSLAKAVIIFGDKDSLLQVIFRLWQFLDIRRIWVTTSQWDIITSNGEFLFNSFHGTLSFSHHYSEIAGFKEFIQTAHPLNYSNTISLAKLWWLNFNCFLSSSNCKSLKTCSRKMLLKWLSRNHFEMSMSDTSYNLYNAVYAVAHSLNELLLQQANTLSNNVGKGLEFDSLQVLSSLKNIHFVNPAGDLVNLNQKENMNINYDIFYTGNFLQSFGIKVKIGKFFKYFTHPQELLMYEELVDWATDVRQTLPSICSIPCHPGFRKSPQEGKAVCCFDCIPCPENEISNMTDMDYCFKCPDNQYANPEGTHCLSKIVTFLSYEDPMGVVLACLALGFSALTAAVFGIFLRNQDTPIVKANNRALSYCLLISLIYCFLCSLLFIGQPHILTCIMQQTIFAVVFTVAISTVLTKTITVVLAFRFTLPSKRMRWLMTSGASILIIPICTMIQLIICGIWLGTSPPFVDSDGHIEHGHILVVCNKGSVIAFYCVLGYLGSIALTSFTVAFLARNLPDTFNEAKFLTFSMLVFCSVWLTFLPVYHSTNGKALVAVEVFCILTSTAGIFLCIFAPKCYIILLKPENKSFHKFRHKNANV", "length": 853 }, "evidence": [ { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F7F1X2-1", "protein_name": "Vomeronasal 2 receptor, 32", "gene_name": "Vom2r32", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFILMVVFFLLHHPLLMANFIDPWCFWRTNLNEVKEKNLDINCAFILGAVQLPMEKDYFNETLNVLKTTKNNKYALALAFSMEEINRNPDLLPNMSLVIKHTLSYCDGNTADHIFKEKFYKPLPNYVCNEETMCSFMLIGLNWVLSLTLFKDLDIFSFPRFLQISYGPFHSIFSDNEQFPYLYQMTPKDTSLALAIVSFLLYFNWNWVGLVISDNDEGNQFLSELKKETQNKEICFAFVNMMSIHEHSSYQKTEMYYNQIVMSSTNIIIIYGKTNSIIELSFRMWVSPVIQRIWVTNSELDFPTSMRDFTHGTFYGTLTFLHHHGEISGFTNFFETWDHLRSRDLNLLIPEWKYFSYDASGSNCKILRNYSSNASLEWITEQKFHMAFNDYSHSIYNAVYAMAHALHETNLQEVDNKEIRNGKGASTHCLKVNSFLRKTHFTNSHGERVIMKQRVRVQEDYDIVHIQNFSQHLRIKMKIGKFSPYFTHGGPFHLYEDMIQLATGSRKMPSSVCSADCSPGFRKSWKEGMAPCCFICSLCPENEISNETNMDQCVNCPEYQYANTEKNKCIQKDVIFLSYEDPLGMALALIAFCLSAFTAVVLWVFVKHHDTPIVKANNRILSYILIMSLMFCFLCSFFFIGHPNRGTCILQQITFGIVFTVAVSTVLAKTITVILAFKLRDPGRSLRNFLVSGAPNYIIPICSLLQCILCAIWLAVSPPFVDIDEHSEHGHIMIVCNKGSIMAFYCVLGYLACLALGSFTTAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTRGRVMVAVEIFSILASSAGMFGCIFAPKIYIILMKPERNSIQKFREKSYF", "length": 849 }, "evidence": [ { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3V911-1", "protein_name": "Vomeronasal 2 receptor, 75", "gene_name": "Vom2r75", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLILMVIFFLLNIPFLLANFMDPRCFWKINLNEIKDEVLGMTCSFILETVQKTMDKDYFNQTLNVLNTTTNHKYALALAFTVDEINRNPDLLPNMSLIIKYNLGHCDGKTVTTLSDLFNPNNHLHFPNYLCNEGIMCLVLLTGPHWRASLYLWISVYVYLSPHFLQLSYGPFYSIFSDNEQYPYLYQMGPKDSSLALAMVSFIIYFKWNWVGLFISDDDQGNQFLSELKKESQTKDICFAFVNMVSVSDVSYYHKTEMYYNQIVMSSTKVIIIYGETNSIIELSFRMWSSPVKQRIWVTTKQFDCPTSKRDLTHGTFYGTLTFLHHYGEISGFKNFVQTRYNLRSTDLYLVTPEWKYFNYEASASNCKILRNYLSNISLEWLMEQKFDMSFSDYSHNIYNAVYAIAHALHEKNLQEVENQAINNAKGENTHCLKLNSFLRKTHFTNSLGNRVIMKQREVVHGDYNIVHMWNFSQRLGIKVKIGQFSPHFPQGQQLHLYVDMTELATGSRKMPSSVCSADCHPGFRRIWKEEMAVCCFVCNPCPENEISNETNMDQCANCPEYQYANTEKNKCIQKGVIVLSYEDPLGMALALIAFCFSAFTVVVFWVFVKHHDTPIVKANNRILSYLLIVSLMFCFLCSFFFIGYPNRATCILQQITFGIFFTVAISTVLAKTITVVLAFKVTDPGRQLRIFLVSGTPNYIIPICSLLQCILCAIWLAVSPPFVDIDEHSEHGHIIIVCNKGSITAFYCVLGYLACLAFGSFTIAFLAKNLPDTFNEAKFLTFSMLVFCAVWVTFLPVYHSTKGKVMVAVEIFSILASSAGMLGCIFAPKVYIILMRPDRNSIHKIREKSYF", "length": 852 }, "evidence": [ { "id": "MGI:3757933", "url": "https://alliancegenome.org/gene/MGI:3757933#orthology", "database": "AGR" }, { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3X931-1", "protein_name": "Vomeronasal 2, receptor 65", "gene_name": "Vmn2r65", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSFMSFFLILEYFLLLSVAHPKCFWRIKQNENKVGDVEDNCFFYIYTRQGPLLNDPFNGNPDILLTTRNIHLILALLFAIKQINRNIHILPNISLIVNVNCAKKEDLQMTNMYSNRDATIPNYNCKHGRRILTVLTGPRWFSSAILGPFLHIFAIPQLYYGPFHPLLSDREHYPYLYQMSPKNTFLTLAMTALVVYFSWNWVGLVISDDELGIEFLFKLRGEMHKHKVCIAFVNMIIQNIQLYQKRAEKYYNQILTSSAKVIIIYGDSDILTVHFRLWQHLGIKRLWITTSHWDENTSKGDLLLSSFNGIFIFSHPHSKIPGFKKFIQTVHPSNYSKDTSLARLWWLYFNCSLPSHCKTLKNCSTKILLEWLSRHQFEVSMSEPSYNLYNAVYAVAYALHEMLIQHTEHWQKDIGKELEFYSWKVAPFLENNKFIIPSEYQYRRGKLDTEYDILYAMDLLPALGLNVKIGKFSQHFLHFQQLYIAEDMIDWTIDIRQTLQSVCSVPCSVGFRKFIQKGKAVCCFDCTPCPENEISNMTDMDQCVKCPNDQYANIKQTHCLKKVVTFLAYEDPLGMTLTCLALLFSALTTVILSILLKHQDNPIVKANNRLLSYILLISLIFCFLCSLLYIGHPHMATCILQQTTFAVVFTVAVSTILAKTITVVMAFKITDPRKKIRQMLVTRAPNYIIPICTMIQLILCGTWIGTSPPFVDSDPHFEHGHIIIVCNKGSVIAFYCVLGYLGLLALGSFTVAFLARNLPDRFNEAKFLTFSMLVFCSVWITFLPVYHSTKGKAMVVVEIFSILTSSAGLLVCIFFPKCFTILLKQKVNFTQKFSDTHSKIEYNH", "length": 845 }, "evidence": [ { "id": "MGI:3642776", "url": "https://alliancegenome.org/gene/MGI:3642776#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3XA45-1", "protein_name": "Vomeronasal 2, receptor 69", "gene_name": "Vmn2r69", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVIWFLKIKLMFCHLSDPSCFWRIKETENDLGDTETYCLFSISTKQGYVKNDYFSWNIDKKVTPKTNHLIFSVYLALEEVNKNCHILPNISLLVNIECNGRKYDEKTGLALKIENIIPNYSCTNERTYLIVLTAPIWAVSTKLGPFLFMSRIPELYCGHFHPLLSDNEEFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGVIVTSDDQGIQFLSELKGEMQKNIVCLSVAIIIQTEMSMALKELSMNYKHISISSAKVVIVYGDKFSPINYALTLWISQGILRIWVSVSQFDMITILGDFLLYSSTGTFIFSHQQPEIPGFEKFIQTVYPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKTIFTWLFRTPFGMAMSDTCYNSYNAIYAVAHSLHEMLMQEVDTWSNNAGKELEFDSWKMFSILKTLKFVNPAGDLVNMNQNLKQATQYNIFYVMDFQKDYGLKMKIGRFSEHLPSGQQLYMSKEMIEWATDIDQILPSICSMPCTPGLRKSPQEGKDICCFVCIPCPENEISNMTNMDQCVKCLEDQYANEDHTLCLQKVVAILDYRDPLGKALAGFALCFSLLTSVVLFVFLKHRDTPIVKANNQTLSIVLLISLIFCFICSLLYIGHPTMVICILQQTTFAIAFTVATSTILAKTITVVLAFKITVPGRRMRWLLVSGAPKYIILICTMIQLILCGIWLGTSPPFVDADVQMVHGHIIIVCNKGSVIAFYCVLGYMGSVALAGFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWMTFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYFILRPQTNSFHKFRKPHAKTENKS", "length": 850 }, "evidence": [ { "id": "MGI:3761311", "url": "https://alliancegenome.org/gene/MGI:3761311#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G5E8Z7-1", "protein_name": "Vomeronasal 2, receptor 75", "gene_name": "Vmn2r75", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNTFSLISVFWFLKISIIFCHLSDPRCFWRIKDAKNDLGDKETYCFFSIYTKQGYVKNDYFSWNLDKKVTPKTNHLIFSVYLAMEEINKNGHILPNISLLVNIECGLELYGERTGLAFKSEEFIPNYYCRNHRKYLIVLTTPKWGVSTSLGPLLYISRVPELYCGHFHLLLNDNEQFPHLYQISPKDTSLPLAMVSLVVHFRWNWIGAIVTNDDHGIQFLSELRGEMQKHIVCLSVAIIIQTEKFMALKEFRMNYNKIAMSSATVVIVYGDKDSPIQFTLIMWKSEGIWRIWVSVSQFDMITVIGDFLLYSSTGSFIFSHQQSEISGFEKFIQTVHPSNYSSEFSLAKLWWTYFTCSLPPSNCKKLKNCPIKTVFKWLFMTPIGMSMSDISYNLYNAMYAVAHSVHEMLLQQVDIWSTNAGTELEFDSWKMFSILKTLKFVNPAGDLVNMNQNLKQDTEYDIFYIPNFQKYYGLKMKIGRFSGYLPSGQQLYMSKEMMEWATDMDQILPSICSMPCRPGLRKSPQEEKDICCFVCNPCPENEISNMTNMDQCVKCPEDQYANEDQTLCLQKVVDVLDYRDPLGKSLAGFALCFSVLTSIVLCVFLKHRESPIVKANNQTLSYVLLISLIFCFICSLLYIGHPTMFICILQQTAFAIAFTVAASTVLAKTITVILAFKITVPGRMRWLLVSGAPKYIIFVCTMIQLIFCGIWLGTSPPFVETDVHMTHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLSRKLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIYAPKCYIILLRPQKNSFYKFRKPHSKSENIS", "length": 853 }, "evidence": [ { "id": "MGI:3648311", "url": "https://alliancegenome.org/gene/MGI:3648311#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N686-1", "protein_name": "Vomeronasal 2, receptor 32", "gene_name": "Vmn2r32", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFIFMGVFFLLNITLLMANFIDPRCFWRINLDEITDEYLGLSCAFILAAVQTPTEKDYFNKTLNFLKTTKNHKYALALVFAMDEINRYPDLLPNMSLIIRYSLGHCDGKTVTPTPYLFHRKKQSPIPNYICNEESMCSFLLSGPNWDESLSFWKYLDSFLSPHILQLSYGSFSSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYLKWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDEVSFPQKTEIYYKQIVKSLTNVIIIYGETYNFIDLIFRMWEPPILQRIWITTKQLNFPTSKTDISHDTFYGSLTFLPHHGEISGFKNFVQTWFHLRNTDLYLVMPEWKYINSEDSASNCKILKNSSSDASFDWLMEQKLDMAFSDNSHNIYNVVHAIAHALHEMNLQQADNQAIDNGKGASSHCLKVNSFLRRTYFTNPLGDKVFMKQRVIMQDEYDIVHFANLSQHLGIKMKLGKFSPYLPHGRHSHLYVDMIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNETNMDQCVNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMFCFLCSFFFIGLPNKVICVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRYFLVSGTLNYIIPICSLLQCVLCAIWLAVSPPFVDIDEHSQHGHIIIVCNKGSVTAFYCVLGYLACLALGSFTLAFLAKNLPDAFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGMLECIFVPKIYIILMRPERNSTQKIREKSYF", "length": 852 }, "evidence": [ { "id": "MGI:1316696", "url": "https://alliancegenome.org/gene/MGI:1316696#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6T2-1", "protein_name": "Vomeronasal 2, receptor 67", "gene_name": "Vmn2r67", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKISFMFCHLSDPKCFWRIKDTKKNLGDTETYCSFSISTKRGYVKNDYFSWNLDKQVTPKTNHLIFSVYLALEEINMNFHILPNISLVVNIECLRKKYDEKTGLALQTEEFIPNYYCTDERRYLIIFTAPIWAVTTRLGTFMFMYSIPELYCGHFHLSLSDNEQFPHLYQISPKDTSLPLAMVSLMVHFRWNWIGAIVTTDDHGIQFLSELRGEMQKHIVCLSFEITILTEHSMARKEFQRYFNRIVMSSAKVVIVYGDYTSPIDLVLHLCKSKGIFRIWVSVSQFDMITKLGDFMLYSSSGTFIFSHQKPELSGFQQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKIVFKWLFMTPLGMAMSDTCYNLYNAIYAVAHSLHEMLLQQIDTWSNNAGKELEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTDYDIFYIMDFQKDYGFKMKIGRFSGHLPSHQQLYMSKEMMEWATDVDQILPSICSMPCRPGLRKSPEEGKDICCFVCNPCHENEISNMTNMDQCVKCQEDQYANEDHTLCLQKVVSILDYRDPLGKALAGIALCFSVLTSGILCIFLKHRETPIVKANNQTLSYVLLISLVFCFICSLLYIGHPTTVICILQPITFAIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLLSGVPKYIVLICTMIQLILCGIWLGTSPPFVDADVYMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFSILASSAGLLLCIFAPKCYIILLRPQTNSFHKFRKTHSKAENIS", "length": 851 }, "evidence": [ { "id": "MGI:3643129", "url": "https://alliancegenome.org/gene/MGI:3643129#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6U5-1", "protein_name": "Vomeronasal 2, receptor 78", "gene_name": "Vmn2r78", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLIVVFLLLKLSFLFCSLSDPRCFWRIKDRENDLGDKETDCFFSIYTKRGYVKNDYFSENLDKKVTLKTIHLISSVYFAAEEINKNIYILPNISLIVKIECNLIADNVKRIWSLKKKEIIPNYYCKNQRRYLIVLTGPIWITSYILGPFLYFSQTPELYCGHFHFLLNDQEQFPHLYQMTPKDTSLPQGMVSLAVHFRWNWVGVIITDDDHGIQFLSELRTGMESNTVCLAFVTIITYNRMLYLKMYHKYYHQITMSSAKVVIVYGDKESPLQFNFILWKSENIQRLWVSVSQFDMITVIRDFMLNSLHGTLIFSHQQSEISGFKQFMQTVHPSNYSNDISLAKMWWTYFKCSLKPPDCKTLKNCPTKTLFKWFFVPPLGMSMSETCYNLYNSVYAVAHSLHEMLLQQVDTCSENDGTVMEFNSWKMFYFLKTIQFVNPAGDLINMNQNRERDTEYDIFYIMDFLKHEGLKMKIGRFSGHFPNGQQLFMSDEMIEWATDIKQTLASACSVPCRPGLRKYFQEGKAVCCFDCYPCPENEISNMTDMDQCVKCPEDEYANTDQTNCLKKVVTFLDYKEPLGMALAVLAVFFSSLTFIILCVFLKHRDTPIVKANNETLSYVLLTSLIFCFICSLLYIGYPTMVSCILQQTTFALVFTVAASCVLAKTITVVLAFKITVPGRRLRWLLLSGAPNYIIPICTTIQMILCGIWLGTSPPFVDADLHMIHEHIIIVCNKGSVTAFYCVLGYMGSLALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWVTFLPVYHSTKGKAMVAVEVFCILASSAGMLLCIFVPKCYLILLRPQINSFHEFRKIHAKSININRM", "length": 853 }, "evidence": [ { "id": "MGI:3761335", "url": "https://alliancegenome.org/gene/MGI:3761335#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N6V1-1", "protein_name": "Vomeronasal 2, receptor 117", "gene_name": "Vmn2r117", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFTLIFLFWLLNIPLLVSDFIYPRCFWKIKQNEDKNRNQGTECTFMIHAVQRPVEKEYFSHILNIQTHTENHKYALALAFSIYEINRNPDILPNMSLTFKFSNYNCHWKSKYNSFIHLSLQNHDILPNYMCKEFTKCAMALTRLNWATTVKLNTILNNFMSQQFLQITYGPFHPVLSDHEKFPYLYQMASDHTSLALALVSFIIHFSWNWVGLVISDNDEDIQFLSYLRREMEKNTVCFAFVNMIPMSMNLYMSRAEVYYNQIMTSSTNVVIIYGDTDSTLAVSFRMWESLGIQRLWITTSQWDVSPSMKDFTFGNEYGTFAFGQHHSEISGFKHFVQTLNSVKCPDEYLVKLEWMHFNCEVSASKCKTLKNCSSNHSLEWLMVHTFDMAFIEGSYDIYNAVYAFAHALHQIAFQKLDNLPKDNGKEHNYSCKKLYSFLRKTQFTNPVGDRVNMNRRNKLQEEYDIFYIWNFPQGLGLRVKIGMFSPYFPNGQQVHLSEDMIEWAKGSAQVPTSVCSAECGPGSRKFRMDGMAACCFHCKPCPENEISNETNVDYCVQCLEDQYANTEQNQCIRKTVVFLSYEEPLGMALSLLSLCFSAFTTVVLGVMVKHHSTPIVKANNRTLTYILLISLIFCFLCPLLFIGHPNAATCILQQITFGVVFTVSVSTVLAKTITVVLAFKITASQRMMKYFLVSGAINYIIPICILIQVIVCAVWLRASPPSVDIDAHSEHGQIIIVCHKGSVNAFYCVLGYLATLAIGSFTLAFFSRNLPGAFNEAKSITFSMLVFCSVWVTFIPVYYSTKGKVMVAVEIFSILASSAGMLGCIFVPKCYTILFRPDQNSLEMIRVKSSSNAHVS", "length": 857 }, "evidence": [ { "id": "MGI:3648766", "url": "https://alliancegenome.org/gene/MGI:3648766#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N702-1", "protein_name": "Vomeronasal 2, receptor 70", "gene_name": "Vmn2r70", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLNSVFWFLKISFIFCHLSDPRCFWRIKDTENNIGDTETYCFFSISTKHGYVKNDYFSWNLDKQVTPKTRHLIFSVYLALEEINDSFHILPNISLVVNIECVLQKYGEKTGLLLRSEKLIPNYYCINERRYLIVLTAPTWAISTKLGPFLFMSRIPEVNQLYCGHFHLPLSNNEQFPHLYQISKKDTSLPLAMVSLVVHFRWNWIGVIITNDDHGIQFLSELRGEMQNNIVCLSVVITIKTQKLVALKELHMNYKQILMSSAKVVIVYGYKDSPIIYALISWKSHGIFRIWVSVSQFDMITIRGDFLLYSSTGTFIFSHQKPEISGFEQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSDCKKLKNCPTKTVFKWLFMTPLGMAMSDTCYNLYNAVYGVAHSLHEMLLQQVDAWSKNAGKELEFDPWKMFSVLKTIQFINPAGDLVNMNQNLRQDVEYDVFYIMDFQKVYGLKMKIGRFSGQLSSGQQLYMSKEIIEWATDIDQILPSICSMPCRPGLRKSPQEEKDICCFGCNPCPENEISNMTNMDQCVKCPENQYANEDHTLCLEKVVAILDYKDPLGKALAGFALCFSVLTSVVLGIFLKNRDTPIVKANNQSLSFVLLISLIFCFICSLLYIGHPTMVICILQQTTFAIVFTVATSTILAKTVIVVLAFKITVPGRRMRWLLEIGAPKYIILICTIIQLILCGIWLGTSPPFVDADVHMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFSILASSAGLLLCIFAPKCYIILLKPQKNSFQKFRKPHAIADNIS", "length": 854 }, "evidence": [ { "id": "MGI:3761314", "url": "https://alliancegenome.org/gene/MGI:3761314#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "K7N741-1", "protein_name": "Vomeronasal 2, receptor 36", "gene_name": "Vmn2r36", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFIFMGVFFLLNITLLMANFIDPRCFWRINLDEITDEYLGLTCAFILAAVQTPTEKDYFNKTLNFLKTTTNHKYALALVFAMDEINRNPDLLPNMSLIIRYALGHCDGKTVTPTPYLFHKKKKSPIPNYFCNEESMCSFLISGPNWKVSLSFWKYLDSFLSPRIFQLTYGPFSSIFSDDEQYPYLYQMAPKDTSLALAMVSFIHYFNWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDDVSFPQNTEMYYNQIVMSSTNVIIIYGETYNFIDLIFRMWEPPILQRIWITTKQLNFPTRKKDISHGTFYGSLTFLPHHGEISGFKNFVQTWFHFRNTDLYLVMPEWKYFNYEDSASNCKILKNNSSDASFDWLMEQKFDMTFSESSHNIYNAVHAIAHALHEMNLQKADNQAIDNGKRASSHCLKVNSFLRRAYFTNPLGDKVFMNQRVIMQDEYDIIHFWNLSQHLGIKMKLGKFSPYLPHGRHSHLYVDMIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNETNMDQCMNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMFCFLCSFFFIGLPNRAICVLQQITFGIVFTVAVSTVLAKTVTVVLAFKVTDPGRRLRNFLVSGTPNYIIPICSLLQCVLCAIWLAVSPPFVDIDEHTLHGHIIIVCNKGSDTAFYCILGYLACLALGSFSLAFLAKNLPDTFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGILGCIFVPKIYIILMLPERNSTQKIREKSYF", "length": 852 }, "evidence": [ { "id": "MGI:3757866", "url": "https://alliancegenome.org/gene/MGI:3757866#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B3-1", "protein_name": "Vomeronasal 2, receptor 68", "gene_name": "Vmn2r68", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVIWFLKVKLMFCHLSDPKCFWRIKDTENNLGDTETYCSFSISTRHGYVKNDYFSWNLDKKVTPKTNHLIFSVYLALDEINMNIHILPNISMVANIECFLQKDGEKTGLALQRKEFIPNYYCTDERRYLIIFTAPIWAVTTRLGPLMFMYSIPELYCGHFHLSLNDNEQFPHLYQISPKDTSLPLAMVSLMVHFRWNWIGAMITNDDHGIQFLSKLRGEMQKHIVCLSFVITILTEHSMAHKEFQRYFNRIVMSSAKVVIVYGDYTSPIDLVLHLCKSKGIFRIWVSVSQFDMITYLGDFMLYSSSGTFIFSHQKPELSGFQQFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPFNCKKLKNCPTKIVFKWLFMTPLGMAMSDTCYNLYNAIHAVAHSLHEMLLQQVDTWSNNAGKELEFDTWKMFSILKTLQFVNPAGDLVNMNQNLKQDTEYEIFYIMDFQKDYGLKMKIGRFSGHLPSRQQLYMSKEMMEWAIDVDQILPSICSMPCRPGLRKSPQEEKDICCFVCNPCLENEISNMTNMDQCVKCREDQYANEHHTLCLQKVVSILDYRDPLGKALAGIALCFSFLTSVVLCIFLKHRETPIVKANNQTLSYVLLISLVFCFICSLLYIGHPTAVICILQQTTFVIAFTVATSTILAKTITVLLAFKITIPGRRMRWLLVSGAPKYIILICTMIQLILCGIWLGTSPPFVDADAHMVHGHIIIVCNKGSVIAFYCVLGYMGSVALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKTMVAVEVFCILASSAGLLLCIFAPKCYIILLRPDINSFQKFRKPHANAENIS", "length": 851 }, "evidence": [ { "id": "MGI:3648297", "url": "https://alliancegenome.org/gene/MGI:3648297#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B5-1", "protein_name": "Vomeronasal 2, receptor 45", "gene_name": "Vmn2r45", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFIFMEVFFLLNITLLMANFIDPRCFWRINLDEIMDEYLGLSCAFILAAVQTPIENDYFNKTLNVLKTTKNHKYALALVFAMDEINRNPDLLPNMSLIIRYSLGHCDGKTVIPTPYLFRKKKESPIPNYFCNEETMCSYLLTGPHWEVSLGFWKHVNSFLSPRILQLTYGPFHSIFSDDEQYPYLYQMAPKDTSLALAMVSFILYFSWNWIGLVIPDDDQGNQFLLELKKQSENKEICFAFVKMISVDDVSFPQNIEMYYNQIVMSSTNVIIIYGETYNFIDLIFRMWEPPILQRIWITTKQLNFPTRKTDISHGTFYGSLTFLPHHGVISGFKNFVQTWFHLRNTDLYLVMQEWKYFNYEDSASTCKIKKNNSSNASFDWLMEQKFDMTFSENSHNIYNAVHAIAHALHEMNLQQADNQAIDNGKGASSHCLKVNSFLRRIYFTNPPGDKVFMKQRVIMQDEYDIVHFVNLSQHLGIKMKLGKFSPYLPHGRHSHLYVDMIELATGRRKMPSSVCSADCSPGFRRLWKEGMAACCFVCSPCPENEISNETNMDQCMNCPEYQYANTEQNKCIQKGVTFLSYEDPLGMALALMAFCFSAFTAVVLCVFVKHHDTPIVKANNRSLSYLLLMSLMFCFLCSFFFIGLPNRAICVLQQITFGIVFTVALSTVLAKTVTVVLAFKVTDPGRRLRNFLVSGTPNYIIPICSLLQCVLCAIWLAVSPPFVDIDEHTLHGHIIIVCNKGSVTAFYCILGYLACLALGSFSVAFLAKNLPDAFNEAKFLTFSMLVFCSVWVTFLPVYHSTKGKHMVAVEIFSILASSAGILGCIFVPKIYIILTRPERNSTQKIREKSYF", "length": 852 }, "evidence": [ { "id": "MGI:3757883", "url": "https://alliancegenome.org/gene/MGI:3757883#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2B7-1", "protein_name": "Vomeronasal 2, receptor 77", "gene_name": "Vmn2r77", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEMFSLIVFFLVLKLSFLFCYLSDPRCFWRIKDRENYLGDKEADCFFSIYTKRGYVKNDYFSENLDKKVTLKTIYLISSVYFAIEEINRNIHILPNISLLVKIDCNLIEDNVERVWSLKKKEIIPNYYCKNQRRYLIVLTGPIWITSYILGPFLYFSRTPELYCGYFHLLLSDQEQFPHLYQMTPKDTSLPLAMVSLAVHFRWNWVGVIITDDDHGIQFLSELRTGMERNTVCLAFVTSITYDKMLYLKMTHKYYHQIIMSSAKVVVVYGDKESPLQLNFMLWKSINIQRLWVSVSQFDMITMMGDFMLNSIHGTLIFSHQQSEMSGFKHFIQRVNPSNYSNDISLAKLWWTYFKCSLPPPDCKTLKNCPTKTLFQWFFEPPLGMSMSETCYNLYNSVYAAAHSIHEMLLQHVDTSSENDENVLEFNSWKMFSFVKNIQFVNPAGDLVNMNQNRKLDTEYDIFYITDFLKHEGLKMKIGRFSGHFPNGQQLFISDEMIEWATDIKQTLASICSVPCRPGLRKYFQEGNSVCCFDCYPCPENEISNMTDMDQCVKCPEDEYANTNQTKCFKKVVTFLAYEDPSGMALAVLAVCFSVLTSVVLCVFLKHRNTPIVKANNETLSYVLLTSLIFCFICSLLYIGYPTMVSCILQQTTFAIVFTVAASCVLAKTITVVLAFKITVPGRRLRWLLLSGAPNYIIPICTMIQMILCGIWLGTSPPFVDADLHMVHGHIIIVCNKGSVIAFYCVLGYMGSLALSSFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFLPVYHSTKGKAMVAVEVFCILASSAGMLVCIFLPKCYIILLRPQINSFHDFRKIHVKVININ", "length": 854 }, "evidence": [ { "id": "MGI:3643879", "url": "https://alliancegenome.org/gene/MGI:3643879#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "L7N2D8-1", "protein_name": "Vomeronasal 2, receptor 71", "gene_name": "Vmn2r71", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSLISVFWFLKVNFIFCHLSDPRCFWRIKETENKLGDKETFCLFSISTKQGYVKNDYFSWNLDKQVTPKINHLIFSVYLALEEINKNCHILPNISLLVNTECNGRKYDEKTGLALKSEKIVPNYSCTNERRYLIVLTAPIWAVSTKLGPFLYISRIPELYCGHFHLLLSDKGQFPHLYQISPKDTSLPLAMVSLFVHFRWNWIGVIITNDDHGIQFLSELKGDMQKSIVCLSVAIIIQTEVYMALKELHMNYKKILMSSAKVVIVYGDKDSPIKYVLTAWKSQGIFRIWVSASQFDMITILGDFLLYSYTGTFIFSHQQPEIPGFEKFIQTVHPSNYSSEFSFAKLWWTYFRCSLPPSNCKKLKNCPTKSVFAWLFRTPLGMAMSDTCYNSYNAIYAVAHSLHEMLLQEVDTWSKNAGKELEFDSWKMFSILKTLKFVNPSGDLVNMNQNLKQDTEYDIFYIMDFQKDYGLKMKIGRFSGHLLSGQQLYMAKEMMEWATDIDQILPSICSVPCSPGLRKSPQEGKDICCFVCNPCPENEISNMTNMDQCVKCLEDQYANEDHTLCLQKVVVIFDYRDPLGKALAGFALCFSVLTSVVLFVFFKHRDTPIVKANNQTLSFVLLISLIFCFICSLLYIGHPTMVTCIVQQITFAIGFTVATSTILAKTVIVVLAFKITVPGRRMRWMPESGAPKYIILICTMIQLILCGIWLGTSPPFVDADVQMVHGHIIIICNKGSVIAFYCVLGYMGSLALASFTVAFLARNLPDTFNEAKLLTFSMLVFCSVWITFIPVYHSTKGKIMAVVEVFCILASSAGLLLCIFAPKCYIILLRPQTNYFHKFWKSHANSENKS", "length": 851 }, "evidence": [ { "id": "MGI:3646472", "url": "https://alliancegenome.org/gene/MGI:3646472#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-283", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-283#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q1LV89-1", "protein_name": "Olfactory receptor CQ3 precursor", "gene_name": "olfcq3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCITLNICLHLSFIFISVNSDSCQIQGHFKLNRMYKDGDYIIGGLFEVQHLKVFPELSFRMEPEQPKCEEFYMSSFQQAQTMVFAIDEINKNPNLLPNITLGYHLYDNCLKLVVAFRAATTLISGTEETFSNFNCTGPPPVIAIVGDPGSTHSIAVSSVLGLFHVPLISYYATCSCLSNRKKYPSFFRTIPSDAFQVRAMVQILKYFGWTWVGVLYSDDDYGIYAAQSFQQEMQRFKGCVAFSEIVPYDNHRDIQRIVAVIKASTARVVVAFSTDLLPLMEELLQQNVTGRQWIASEAWSTSPVLHLPRFVPLVRGTLGIAIHRGKIKGLHEFLLHIQPDNDPTNNMVRIFWENMFGCSFEKGNGYGEKMCTAQEDLNITVNEYNDVSELRASYNVYKAVYALAHALHDLMQCEEGRGPFSGNSCADITKLKPWQMVPYLQKVNFTTGFGDHVSFDENGDALAIYDVMNWHPSSDGLIVVRTVGVVDEGASAGRVLTLDEDAIYWNFETKKPPRSVCSESCPPGTRRAMRKGLPVCCFDCLPCADGEISNMSDATECTSCPNEFWSSPKKDQCVPKEVEFLSYEDPLGISLTTASLLGTCFCALVLAVFAHHHNTPVVRANNSELSFLLLLSLKLCFLCVLLFIGRPQLWTCQLRHAMFGISFVLCVSSILVKTMVVIAVFKSSRPEGKSAVKWFGAVQQRGTVLVLTAVQIVICVVWLSTASPTPHKNILYVRSKIVFECSIGSMAGFAILLGYIGILAAVSFLLAFLARNLPDNFNEAKFITFSMLIFSAVWIAFIPAYVSSPGKYSVAVEIFAILASSFGLLVAIFVPKCYIIILHPERNTKKAIMGRTAEK", "length": 855 }, "evidence": [ { "id": "MGI:3757950", "url": "https://alliancegenome.org/gene/MGI:3757950#orthology", "database": "AGR" }, { "id": "MGI:3644480", "url": "https://alliancegenome.org/gene/MGI:3644480#orthology", "database": "AGR" }, { "id": "MGI:3695438", "url": "https://alliancegenome.org/gene/MGI:3695438#orthology", "database": "AGR" }, { "id": "MGI:3704110", "url": "https://alliancegenome.org/gene/MGI:3704110#orthology", "database": "AGR" }, { "id": "RGD:1595960", "url": "https://alliancegenome.org/gene/RGD:1595960#orthology", "database": "AGR" }, { "id": "RGD:1560365", "url": "https://alliancegenome.org/gene/RGD:1560365#orthology", "database": "AGR" }, { "id": "RGD:1559147", "url": "https://alliancegenome.org/gene/RGD:1559147#orthology", "database": "AGR" }, { "id": "MGI:3761332", "url": "https://alliancegenome.org/gene/MGI:3761332#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "A0T301", "url": "https://www.uniprot.org/uniprotkb/A0T301" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A0T301", "url": "https://www.uniprot.org/uniprotkb/A0T301" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 138, "end_pos": 140, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 456, "end_pos": 458, "annotation": "n_glycosylation_sequon" }, { "start_pos": 562, "end_pos": 564, "annotation": "n_glycosylation_sequon" }, { "start_pos": 633, "end_pos": 635, "annotation": "n_glycosylation_sequon" }, { "start_pos": 6, "end_pos": 8, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A0T301", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0T301" }, { "id": "PS50259", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50259" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 3 profile", "eco_id": "ECO_0000259", "start_pos": 599, "end_pos": 864, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 138, "end_pos": 140 }, { "start_pos": 294, "end_pos": 296 }, { "start_pos": 456, "end_pos": 458 }, { "start_pos": 562, "end_pos": 564 }, { "start_pos": 633, "end_pos": 635 }, { "start_pos": 6, "end_pos": 8 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A1A5Y5-1", "uniprot_ac": "A1A5Y5", "uniprot_id": "TT39A_DANRE", "mass": { "chemical_mass": 64756.0, "monoisotopic_mass": 64756.0 }, "refseq": { "ac": "NP_001073553", "name": "tetratricopeptide repeat protein 39A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073553" }, "gene_names": [ { "name": "ttc39a", "type": "recommended", "evidence": [ { "id": "A1A5Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5Y5" } ] }, { "name": "im:7136100", "type": "synonym", "evidence": [ { "id": "NP_001073553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073553" } ] }, { "name": "im:7138209", "type": "synonym", "evidence": [ { "id": "NP_001073553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073553" } ] }, { "name": "ttc39a", "type": "synonym", "evidence": [ { "id": "NP_001073553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073553" } ] }, { "name": "zgc:158403", "type": "synonym", "evidence": [ { "id": "NP_001073553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073553" }, { "id": "A1A5Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5Y5" } ] } ], "protein_names": [ { "name": "Tetratricopeptide repeat protein 39A", "type": "recommended", "evidence": [ { "id": "A1A5Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5Y5/entry#names_and_taxonomy" } ] }, { "name": "TPR repeat protein 39A", "type": "synonym", "evidence": [ { "id": "NP_001073553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073553" }, { "id": "A1A5Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A1A5Y5/entry#names_and_taxonomy" } ] }, { "name": "tetratricopeptide repeat protein 39A", "type": "synonym", "evidence": [ { "id": "NP_001073553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073553" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC128859.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476749, SAMEA4476777 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC128859.1. On Mar 11, 2007 this sequence version replaced XP_001345119.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001073553", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073553" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A1A5Y5", "url": "https://www.uniprot.org/uniprotkb/A1A5Y5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ttc39a", "url": "https://www.uniprot.org/uniprotkb/A1A5Y5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061215-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061215-116", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A1A5Y5", "url": "https://alphafold.ebi.ac.uk/entry/A1A5Y5", "database": "AlphaFoldDB", "categories": [] }, { "id": "100320357", "url": "https://www.ncbi.nlm.nih.gov/gene/100320357", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "790939", "url": "https://www.ncbi.nlm.nih.gov/gene/790939", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:790939", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:790939", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A1A5Y5", "url": "https://www.orthodb.org/?gene=A1A5Y5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31859", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31859", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31859:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31859:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31859:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31859:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10300", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10300", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A1A5Y5", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A1A5Y5", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001073553", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001073553", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58G953", "url": "https://www.uniprot.org/uniprotkb/A0AC58G953", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G953-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G953-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G961", "url": "https://www.uniprot.org/uniprotkb/A0AC58G961", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G961-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G961-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A1A5Y5", "url": "https://www.uniprot.org/uniprotkb/A1A5Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A1A5Y5-1", "url": "https://www.uniprot.org/uniprotkb/A1A5Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061215-116", "url": "https://zfin.org/ZDB-GENE-061215-116", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSTGKNAPVTENSRQMSLQACLDECMEALDLFLNNHFNESLDKLRPRSKESMYHALIYATVLEMQAMMTFQQDDIVHAGNTMKSAQEVCQRFRKKSGGLGSRGANDDLSEEQIHAEVCYAECLLHRAALTFLQDENMVSFIKGGIKVRNSYLIYKELHAFIQSDATFKGPNHKHLEGGVSFGIGAFNLTLSLFPARILKLLEFAGFSGDKEFGISQLYTGATSHTLRSMLCALLLLCFYTFLSFILGTGEGEVEEAERLLKPFRLRYPRGAIFLFFAGRAEEIKGNIDEAVALFEDGCKAQQVWKQFHHMCYWELMWCFTFKRYWKMAYFYADLLSQESRWSKAMYVYMKAAYLSMLPDSESRPFGDNEVDLFRQVPTYKQKIAGKSPPTEKFAIRKARRYKASNPVRLPVPVLEMMYMWNGFSMISKQPELTEGMMETLLEAERTLRASPDNEYTVDDTCLIQLLKGLCLKNQGQMQAAEDCFNQVYISEKKLKFDHYLVPNALLEMSLLFIDTGRKEQAIKLLQKAKNNYKVYSMESRTQFRVHAALTKLKADVSDQEEITAL", "length": 565, "header": "sp|A1A5Y5-1|TT39A_DANRE Isoform 1 of Tetratricopeptide repeat protein 39A OS=Danio rerio OX=7955 GN=ttc39a PE=2 SV=1 CANONICAL=A1A5Y5-1" }, "isoforms": [ { "isoform_ac": "A0AC58G953-1", "url": "https://www.uniprot.org/uniprotkb/A1A5Y5/entry#A0AC58G953-1", "sequence": { "sequence": "MSFWRRNKKNDDQKNQLKTEESLDSPTSPSHRVDYRNSLLTGLPTKTVRQLQLIQNAAPRILPRTRKSPIIEKDGLDSVISDYGSEKPDLSADLQDCMAALDLFLQNQFDESLSRLRSRNKDSMYHALTYATILEMQAMMTFNPEDIFAAGNTMKEAQAVCQRYRKKSSFNSKNFTEEELHAEVCYAECLLQRAALTFLQDENMISFIKGGMKVRNSYQIYKELHTILKSSGYVQGDNHGHFEGGVKLGIGAFNLMLSLLPTRTLRLLEFVGFSGNKEFGLEQLQEGCSEHTFRSFLCNMLLLCYHTFMSFILGTGEGDVEDAEKLLQPYLKKYPKGSIFLFFAGRIEEIKGNLDAAIKRFEECCEAQQDWKQFHHMCYWELMWCFTYKRHWKMAYFYADLLSKENNWSKATYAYMKGAYLSMLSREECQPFGENEVALFRQVPSLKQKIAGKSLPTEKFAIRKARRYNTDNVIPLPAPPLEMMYIWNGYTVIGKHKDLTEGMLKTLDEAQQTLEQTPRTEFTTDDQCVVSLLKGLCLKHLGYKEEAEHYFTLVLCNESLIKYDHYLVPNALLEHGLLCLEEGRIDEAIKLLEAAKQNYKNYSMESRTHFRIQAALHKARGTAVNGYHSSPSSP", "length": 634, "header": "tr|A0AC58G953-1|A0AC58G953_DANRE Computationally mapped isoform of Tetratricopeptide repeat protein 39A isoform X1 OS=Danio rerio OX=7955 GN=ttc39a PE=3 SV=1 CANONICAL=A1A5Y5-1" }, "locus": {} }, { "isoform_ac": "A0AC58G961-1", "url": "https://www.uniprot.org/uniprotkb/A1A5Y5/entry#A0AC58G961-1", "sequence": { "sequence": "MSFWRRNKKNDDQKNQLKTEESLDSPTSPSQVDYRNSLLTGLPTKTVRQLQLIQNAAPRILPRTRKSPIIEKDGLDSVISDYGSEKPDLSADLQDCMAALDLFLQNQFDESLSRLRSRNKDSMYHALTYATILEMQAMMTFNPEDIFAAGNTMKEAQAVCQRYRKKSSFNSKNFTEEELHAEVCYAECLLQRAALTFLQDENMISFIKGGMKVRNSYQIYKELHTILKSSGYVQGDNHGHFEGGVKLGIGAFNLMLSLLPTRTLRLLEFVGFSGNKEFGLEQLQEGCSEHTFRSFLCNMLLLCYHTFMSFILGTGEGDVEDAEKLLQPYLKKYPKGSIFLFFAGRIEEIKGNLDAAIKRFEECCEAQQDWKQFHHMCYWELMWCFTYKRHWKMAYFYADLLSKENNWSKATYAYMKGAYLSMLSREECQPFGENEVALFRQVPSLKQKIAGKSLPTEKFAIRKARRYNTDNVIPLPAPPLEMMYIWNGYTVIGKHKDLTEGMLKTLDEAQQTLEQTPRTEFTTDDQCVVSLLKGLCLKHLGYKEEAEHYFTLVLCNESLIKYDHYLVPNALLEHGLLCLEEGRIDEAIKLLEAAKQNYKNYSMESRTHFRIQAALHKARGTAVNGYHSSPSSP", "length": 633, "header": "tr|A0AC58G961-1|A0AC58G961_DANRE Computationally mapped isoform of Tetratricopeptide repeat protein 39A isoform X2 OS=Danio rerio OX=7955 GN=ttc39a PE=3 SV=1 CANONICAL=A1A5Y5-1" }, "locus": {} }, { "isoform_ac": "A1A5Y5-1", "url": "https://www.uniprot.org/uniprotkb/A1A5Y5/entry#A1A5Y5-1", "sequence": { "sequence": "MSTGKNAPVTENSRQMSLQACLDECMEALDLFLNNHFNESLDKLRPRSKESMYHALIYATVLEMQAMMTFQQDDIVHAGNTMKSAQEVCQRFRKKSGGLGSRGANDDLSEEQIHAEVCYAECLLHRAALTFLQDENMVSFIKGGIKVRNSYLIYKELHAFIQSDATFKGPNHKHLEGGVSFGIGAFNLTLSLFPARILKLLEFAGFSGDKEFGISQLYTGATSHTLRSMLCALLLLCFYTFLSFILGTGEGEVEEAERLLKPFRLRYPRGAIFLFFAGRAEEIKGNIDEAVALFEDGCKAQQVWKQFHHMCYWELMWCFTFKRYWKMAYFYADLLSQESRWSKAMYVYMKAAYLSMLPDSESRPFGDNEVDLFRQVPTYKQKIAGKSPPTEKFAIRKARRYKASNPVRLPVPVLEMMYMWNGFSMISKQPELTEGMMETLLEAERTLRASPDNEYTVDDTCLIQLLKGLCLKNQGQMQAAEDCFNQVYISEKKLKFDHYLVPNALLEMSLLFIDTGRKEQAIKLLQKAKNNYKVYSMESRTQFRVHAALTKLKADVSDQEEITAL", "length": 565, "header": "sp|A1A5Y5-1|TT39A_DANRE Isoform 1 of Tetratricopeptide repeat protein 39A OS=Danio rerio OX=7955 GN=ttc39a PE=2 SV=1 CANONICAL=A1A5Y5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:790939", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:790939", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BE96-1", "protein_name": "Tetratricopeptide repeat protein 39A isoform X3", "gene_name": "ttc39a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MCVCCSQREAAVLLTGAKAKACSYTHCEVLCVSFSCLLLSSISLYQMKMSREAETLSNGSEKPDLSADLQDCMAALDLFLQNQFDESLSRLRSRNKDSMYHALTYATILEMQAMMTFNPEDIFAAGNTMKEAQAVCQRYRKKSSFNSKNFTEEELHAEVCYAECLLQRAALTFLQDENMISFIKGGMKVRNSYQIYKELHTILKSSGYVQGDNHGHFEGGVKLGIGAFNLMLSLLPTRTLRLLEFVGFSGNKEFGLEQLQEGCSEHTFRSFLCNMLLLCYHTFMSFILGTGEGDVEDAEKLLQPYLKKYPKGSIFLFFAGRIEEIKGNLDAAIKRFEECCEAQQDWKQFHHMCYWELMWCFTYKRHWKMAYFYADLLSKENNWSKATYAYMKGAYLSMLSREECQPFGENEVALFRQVPSLKQKIAGKSLPTEKFAIRKARRYNTDNVIPLPAPPLEMMYIWNGYTVIGKHKDLTEGMLKTLDEAQQTLEQTPRTEFTTDDQCVVSLLKGLCLKHLGYKEEAEHYFTLVLCNESLIKYDHYLVPNALLEHGLLCLEEGRIDEAIKLLEAAKQNYKNYSMESRTHFRIQAALHKARGTAVNGYHSSPSSP", "length": 609 }, "evidence": [ { "id": "MGI:2444350", "url": "https://alliancegenome.org/gene/MGI:2444350#orthology", "database": "AGR" }, { "id": "HGNC:18657", "url": "https://alliancegenome.org/gene/HGNC:18657#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2ACP1-1", "protein_name": "Tetratricopeptide repeat protein 39A", "gene_name": "Ttc39a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGQKGHKDSLYDCKGSPVSSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQSLCQRHRRKSSMTDSFSNLVHRPTIDQFTEEEIHAEVCYAECLLQRAALTFLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYSKGESHRHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGATGHSFRAVLCVMLLLCYHTFLTFVLGTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEAIKGNIDAAVRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMAYFYADLLSKENSWSKATYIYMKAAYLSMFGKEDYKPFGDNEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYLSPNPISLPIPALEMMYIWNGYAVIGKQPTLTDGMLEVITKAEEMLAMGPENEYSADDDCLVKLLKGLCLKYLGRIQEAEENFRSISANEKKIKYDHYLIPNALLELALLFMEQGRNEEAIKLLESAKQNYKNYSMESRTHFRIQAATLQARSSLEDGNRSLVSSVSL", "length": 578 }, "evidence": [ { "id": "MGI:2444350", "url": "https://alliancegenome.org/gene/MGI:2444350#orthology", "database": "AGR" }, { "id": "HGNC:18657", "url": "https://alliancegenome.org/gene/HGNC:18657#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061215-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061215-116#orthology", "database": "AGR" }, { "id": "RGD:1311126", "url": "https://alliancegenome.org/gene/RGD:1311126#orthology", "database": "AGR" }, { "id": "SGD:S000001726", "url": "https://alliancegenome.org/gene/SGD:S000001726#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZC96-1", "protein_name": "Tetratricopeptide repeat protein 39B", "gene_name": "Ttc39b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALVGSRVELDADEDIFEDALETISRSPSDMATSGFHFVPCDTKRTSRQLGAPAVGRAEGSSAKVDLKSGLEECAAALNLFLSNRFKDALELLRPWAKESMYHALGYSTIVVLQAVMTFEQQDIQNGISAMKDALQTCQKYRKKCTVVESFSSLLSRGSLEQLSEEEMHAEICYAECLLQKAALTFVQDENMINFIKGGLKIRTSYQIYKECLSILHVIQKNKEEQHFFYEFEGGVKLGTGAFNLMLSLLPARIIRLLEFIGFSGNRDLGLLQLREGASGSSMRSPLCCLTILAFHTYISLILGTGEVNVAEAESLLAPFLQQFPNGSLILFYHARIELLKGNAEKAQETFRKCISVQEEWKQFHHLCYWELMWIYIYQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLPEEEVAVTKENVVSLFRQVDGLKQRIAGKSLPTEKFAVRKARRYSPSSGVPGKLVLPALEMMYVWNGFSIVGKRKDLSENLLVTVEKAEEALQNQNFTDYSVDDECLVKLLKGCCLKNLQRPLQAELCFNHVLESEKLLKYDHYLVPFTLFELAFLYKSQGEIDKAIKVLETARNNYKDYSLESRLHFRIQAALHLWKKPSSD", "length": 617 }, "evidence": [ { "id": "SGD:S000003618", "url": "https://alliancegenome.org/gene/SGD:S000003618#orthology", "database": "AGR" }, { "id": "SGD:S000001726", "url": "https://alliancegenome.org/gene/SGD:S000001726#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D4A7N7-1", "protein_name": "Tetratricopeptide repeat domain 39D", "gene_name": "Ttc39d", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRYQRHEDNDEYLLNTLSLSEGETERMARVTRSVNLRDSETEDKFEDAHEIIPVATTMSLLSSLEECTTGLYLFLNNRFSDAINLIHPWSKNSSYHALIYSMFMVVKAILTFEPQDIQIGMNAAKEALKTCNNFRKKPRIMTLSRLVSRQGIKSIKEEELHAEVCYAECLVLKSAITFIQDDSLLNFLKSGVNVGSSYQIYKDCQQVLELMPENQSKTHRHLNGGIKFGVGVFNLMFSLVPPKSLKLLNMVGYSGDREVGLALLHDSASEPHINNILSVFTLLFYYNYVRVVVGVEKASTAATESLFLVYLEKFPNCVVLKFFRARFNMLNGNFESAKLKLQECIITQNEWKQVHHLCYWELMWCHIFLQNWKQAYNYANLLFQHSRWSKAIYTYSKAIILALLPPDSVDSENESLSSYFLRVDSLRIKFLGSSVPIEKFIAEKSQRYGTTTGWFTAQPLLEFIYAWSGFRVMSKKIELISSWLMIIDKGKELLNENPNEEYGVDDMSLLNLLKGLCLKHLGKHLKAEHYFIRVIRKERSLKYDHYLVPYSYYELGMLHYLKGDYTNATKNLDNIKNYKDYSMEARLQFRAHIALEQIAKLEK", "length": 604 }, "evidence": [ { "id": "SGD:S000001726", "url": "https://alliancegenome.org/gene/SGD:S000001726#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F7F7D5-1", "protein_name": "Tetratricopeptide repeat domain 39A", "gene_name": "Ttc39a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAFLTTWKRAASRKRDRRSPVSSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQSLCQRHRRKSSVTDSFSSLVHRPTIDQFTEEEIHAEVCYAECLLQRAALTFLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYSKGESHRHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGATGHSFRAVLCVMLLLCYHTFLTFVLGTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEAIKGNIDAAVRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMAYFYADLLSKENSWSKATYIYMKAAYLSMFGKEDYKPFGDDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYLSPNPISLPIPALEMMYIWNGYAVIGKQQKLTDGMLAVITKAEEMLAMGPENEYSADDDCLVKLLKGLCLKYLGRIQEAEENFRSISANEKKIKYDHYLIPNALLELALLFMEQGRNEEAIKLLDSAKQNYKNYSMESRTHFRIQAATLQARSSLGDGSRSPVSSVSL", "length": 581 }, "evidence": [ { "id": "MGI:2444350", "url": "https://alliancegenome.org/gene/MGI:2444350#orthology", "database": "AGR" }, { "id": "HGNC:18657", "url": "https://alliancegenome.org/gene/HGNC:18657#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061215-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061215-116#orthology", "database": "AGR" }, { "id": "RGD:1311126", "url": "https://alliancegenome.org/gene/RGD:1311126#orthology", "database": "AGR" }, { "id": "SGD:S000001726", "url": "https://alliancegenome.org/gene/SGD:S000001726#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P36114-1", "protein_name": "IML2-like protein YKR018C", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFKVFGFGAKEEIPELSQEEKTKAILKQAHDFEQALRAMDYVLDDNADEGLALLDESDAKEASDQTINALARGVIEFLEATLGFEAEEMKKASATLAKAEALSLKSRERAQKIGLKSSSLYPPGTVYAVTYTESCLLHALLMIFSESMMEAAKAILKLRKSYYMLQEILETIKAANKAKKLKITSGSEDKESTPATFITGGDAFNSVDIPYELTPEEQKDKDLLQFAEQIHSMRTERLSGAHIGNSPAINRLRGELGLQAMEDLPEEEITDHKVLSDDIDLSQATIDEFVHSGVNLCFGILQVVISLLPPAIGAVLSVVGFRGSREEGLRLVWKATKQRNVHGCIGLLALMFYYDGPFQFTDDDFDIPAAVKDSSNSEDSEDEEMDGPTLLHPGKILEDALLQSRALFPNSALWLLNEARMLSGKGRLEEAVALMDSIDVSKIRMRQVKSLMIFDRAITLIHLHQYDRAAEDILSLLDISDWSHAFYTYFAGCCYLENWRMCEMGLMKSDKKDEYQKKAEELIFTSVNLLGKKTFKSKNLPLDRFILRKVEQFKAKKEELGVENPLDGIATSPVHEIAYFYNGYNRMSEEHLELTKKMLTEYRNPAIEALDSDQELIKDLLVSLTLRRLGHIQEGCDILDEKVLPKFFSIQNGKVKYIKKTEDPWAYPTALYERALFTWKLEGMDGLPESKEWLLRAQGYADDYELSTRVGMKIKAAIDRVDHSL", "length": 725 }, "evidence": [ { "id": "MGI:2444350", "url": "https://alliancegenome.org/gene/MGI:2444350#orthology", "database": "AGR" }, { "id": "HGNC:18657", "url": "https://alliancegenome.org/gene/HGNC:18657#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061215-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061215-116#orthology", "database": "AGR" }, { "id": "RGD:1311126", "url": "https://alliancegenome.org/gene/RGD:1311126#orthology", "database": "AGR" }, { "id": "SGD:S000001726", "url": "https://alliancegenome.org/gene/SGD:S000001726#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P47031-1", "protein_name": "Inclusion body clearance protein IML2", "gene_name": "IML2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFRVFGSFGSKGNQSSGEEQSTKTKQVLKQANDFEIALKAMDFVLDDRTDEGLNLLKKAEMETGSDQTILTLARGVIEFLQATLSFETEEMKRAAITLGKAEQMSWKSKQNAEKTNFRSSSIYPPGTVYAVTYTESCLLHALLMLFSESMMEAAKALLKLRRAYTMLQDIMVTVKKAERSKNSSSPSPSEKSQESCGSFVSAETTFISVDIPYKLSSEDKSNPLLLEFAEKIYTMRMGRLSGAHIGNTPSFHRLRDDLGLQTTPSQASDRHSVSDDFDLEQATIDEFIHSGANLCYGILQVVLSLLPPAIGAVLSIVGFKGSREEGLRLVWKATKERNVHGCIGLLGLMFYYDGPFQFTDADFDIPPNDNGSRALNKSRTNDSSLLPGYMDSATLLHPGKILEDALLKARALFPNSALWLLNEAKMLAGKGRLRDSLALMDSIDVNSIRMRQVKSLMVFERAILLVNLHEYNRAADDLISLLDISDWSHALYTYFAGCCYLENWRMTQLGLLNDGKEQFYKERARELIFDAPSLLGKKTFKSKNLPLDRFMLRKVQQFNNMQKKLNLQEPLDSIATSPVHELAYFYNGYNRMTENDLILTKKMLTEYHNPAIDSEDPDQELIRNLLLSLTLRRLGDAERGLALLDDIVLPKIFYIQNGKVKYFKKTEDPWAYPAALYERALFCWKLGGMESLNECREWLLRAQNYAADYELSTRIGMKIKAALDRVENALA", "length": 731 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-061215-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061215-116#orthology", "database": "AGR" }, { "id": "SGD:S000003618", "url": "https://alliancegenome.org/gene/SGD:S000003618#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q0VGK2-1", "protein_name": "Tetratricopeptide repeat protein 39C", "gene_name": "Ttc39c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFGASFVSFLNAMMTFEEEKMQLACDDLKTTEKLCESEEAGVIETIKNKIKKNVDARKSTPSMVDRLQRQIIIADCQVYLAVLSFVKQELSAYIKGGWILRKAWKIYNKCYVDINALQELHQKTLTEEPLSSDAANDNHIVAEGVTEEALSRLKGAVSFGYGLFHLCISMVPPNLLKIINLLGFPGDRLQGLSSLTYASESKDMKAPLATLALLWYHTVVRPFFALDGSDNKGGLDEAKAILLRKESAYPNSSLFMFFKGRIQRLECQINSALTSFHTALELAVDQREIQHVCLYEIGWCSMIELNFKDAFDSFERLKNESRWSQCYYAYLTAVCQGATGDVDGAQLIFKEVQKLFKRKNNQIEQFSVKKAERFRKQTPTRALCVLASIEVLYLWKALPNCSLPNLQRMSQACHEVDDSSVVGLKHLLLGAIHKCLGNSQDAVQFFQRAAKDESCRQNNSYVQPYACYELGCLLLDRAETVARGRTLLLQAKEDFSGYDFENRLHVRVHAALASLRELVPQ", "length": 522 }, "evidence": [ { "id": "SGD:S000003618", "url": "https://alliancegenome.org/gene/SGD:S000003618#orthology", "database": "AGR" }, { "id": "SGD:S000001726", "url": "https://alliancegenome.org/gene/SGD:S000001726#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1LXE6-1", "protein_name": "Tetratricopeptide repeat protein 39C", "gene_name": "ttc39c", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAGPDSPQQQQVEEKAEQIDDAELAFQGINMLLNNGFRESDELFRRYRTHSPLMSFGASFVSFLNAMMTFEEEKMQMASDDLRTTEKLCESDNAGVIETIRNKIKKSMDSGRSGVEIVDRLQRQIIVADCQVYLAVLSFVKQELSAYIKGGWILRKAWKMYNKCYSDISQLQEACRRRSSDQQGALASDQANHNTSTGSGGRVTDEVLDRLKGSVSFGYGLFHLCISMVPPHLLKIVNLLGFPGDRHQGLASLAYASESKDMKAPLATLALLWYHTVVQPFFALDGSDSRAGLLEAKAILQKKAMVYPNSSLFIFFKGRVQRLECQINSALASFQDALEFASDQREIQHVCLYEIGWCSMIEMSFEDAFRSFERLKNESRWSQCYYAYLTGVCQGASGDLEGAKGVFRDVQKLFKRKNNQIEQFALKRAEKLRKVSLTRELCILGVVEVLYLWKALPNCSSSKLQLMNQVLQGLDDQSSIGLKHLLLGAIQKCLGNIKDALQSFQLAAQDEYGRLNNSYVQPYACYELGCVLLAKPETLSKGRSLLLQAKENYAGYDFENRLHVRIHSALASIKEVVPH", "length": 579 }, "evidence": [ { "id": "SGD:S000003618", "url": "https://alliancegenome.org/gene/SGD:S000003618#orthology", "database": "AGR" }, { "id": "SGD:S000001726", "url": "https://alliancegenome.org/gene/SGD:S000001726#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5SRH9-1", "protein_name": "Tetratricopeptide repeat protein 39A", "gene_name": "TTC39A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQKGHKDSLYPCGGTPESSLHEALDQCMTALDLFLTNQFSEALSYLKPRTKESMYHSLTYATILEMQAMMTFDPQDILLAGNMMKEAQMLCQRHRRKSSVTDSFSSLVNRPTLGQFTEEEIHAEVCYAECLLQRAALTFLQGSSHGGAVRPRALHDPSHACSCPPGPGRQHLFLLQDENMVSFIKGGIKVRNSYQTYKELDSLVQSSQYCKGENHPHFEGGVKLGVGAFNLTLSMLPTRILRLLEFVGFSGNKDYGLLQLEEGASGHSFRSVLCVMLLLCYHTFLTFVLGTGNVNIEEAEKLLKPYLNRYPKGAIFLFFAGRIEVIKGNIDAAIRRFEECCEAQQHWKQFHHMCYWELMWCFTYKGQWKMSYFYADLLSKENCWSKATYIYMKAAYLSMFGKEDHKPFGDDEVELFRAVPGLKLKIAGKSLPTEKFAIRKSRRYFSSNPISLPVPALEMMYIWNGYAVIGKQPKLTDGILEIITKAEEMLEKGPENEYSVDDECLVKLLKGLCLKYLGRVQEAEENFRSISANEKKIKYDHYLIPNALLELALLLMEQDRNEEAIKLLESAKQNYKNYSMESRTHFRIQAATLQAKSSLENSSRSMVSSVSL", "length": 613 }, "evidence": [ { "id": "MGI:2444350", "url": "https://alliancegenome.org/gene/MGI:2444350#orthology", "database": "AGR" }, { "id": "HGNC:18657", "url": "https://alliancegenome.org/gene/HGNC:18657#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061215-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061215-116#orthology", "database": "AGR" }, { "id": "RGD:1311126", "url": "https://alliancegenome.org/gene/RGD:1311126#orthology", "database": "AGR" }, { "id": "SGD:S000001726", "url": "https://alliancegenome.org/gene/SGD:S000001726#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5VTQ0-1", "protein_name": "Tetratricopeptide repeat protein 39B", "gene_name": "TTC39B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDAVLACRLRGRGNRVAALRPRPRPGGSAGPSPFALLCAGLSPEPRAGVGSEFPAWFLGGSSQRRNMALLGSRAELEADEDVFEDALETISISSHSDMATSSLHFASCDTQQAPRQRGASTVSSSSSTKVDLKSGLEECAVALNLFLSNKFTDALELLRPWAKESMYHALGYSTIVVLQAVLTFEQQDIQNGISAMKDALQTCQKYRKKYTVVESFSSLLSRGSLEQLSEEEMHAEICYAECLLQKAALTFVQDENMINFIKGGLKIRTSYQIYKECLSILHEIQKNKLQQEFFYEFEGGVKLGSGAFNLMLSLLPARIIRLLEFIGFSGNRELGLLQLREGASGRSMRSALCCLTILAFHTYISLILGTGEVNVAEAERLLAPFLQQFPNGSLVLFYHARIELLKGNLEEAQEVFQKCISVQEEWKQFHHLCYWELMWINVFQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLPEEDVVATNENVVTLFRQVDSLKQRIAGKSIPTEKFAVRKARRYSASLPAPVKLILPALEMMYVWNGFSIVSKRKDLSENLLVTVEKAEAALQSQNFNSFSVDDECLVKLLKGCCLKNLQRPLQAELCYNHVVESEKLLKYDHYLVPFTLFELASLYKSQGEIDKAIKFLETARNNYKDYSLESRLHFRIQAALHLWRKPSSD", "length": 682 }, "evidence": [ { "id": "SGD:S000003618", "url": "https://alliancegenome.org/gene/SGD:S000003618#orthology", "database": "AGR" }, { "id": "SGD:S000001726", "url": "https://alliancegenome.org/gene/SGD:S000001726#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BYY4-1", "protein_name": "Tetratricopeptide repeat protein 39B", "gene_name": "Ttc39b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALVGSRVELDADEDIFEDALETISRSPSDMATSGFHFVPCETKRTSRQLGASAMGRPEGSSAKVDLKSGLEECAEALNLFLSNKFKDALELLRPWAKESMYHALGYSTIVVLQAVMTFEQQDIQNGISAMKDALQTCQKYRKKCTVVESFSSLLSRGSLEQLSEEEMHAEICYAECLLQKAALTFVQDENMINFIKGGLKIRTSYQIYKECLSILHVIQKNKQEQHFFYEFEGGVKLGTGAFNLMLSLLPARIIRLLEFIGFSGNRDLGLLQLREGASGSSMRSPLCCLTILAFHTYISLILGTGEVNVVEAESLLAPFLQQFPNGSLILFYHARIELLKGNTEKAQETFRKCISVQEEWKQFHHLCYWELMWIHIYQQNWMQAYYYSDLLCKESKWSKATYVFLKAAILSMLPEEEVAATKENVVSLFRQVDGLKQRIAGKSLPTEKFAVRKARRYSPPSGVPGKLVMPALEMMYVWNGFSIVGKRKDLSENLLVTVEKAEEALQNQDFTDYSVDDECLVKLLKGCCLKNLERPLQAELCFNHVVESEKLLKYDHYLVPFTLFELAFLYKSQGEIDKAIKVLETARNNYKDYSLESRLHFRIQAALHLWKKPSTD", "length": 617 }, "evidence": [ { "id": "SGD:S000003618", "url": "https://alliancegenome.org/gene/SGD:S000003618#orthology", "database": "AGR" }, { "id": "SGD:S000001726", "url": "https://alliancegenome.org/gene/SGD:S000001726#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N584-1", "protein_name": "Tetratricopeptide repeat protein 39C", "gene_name": "TTC39C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGSEQQRPRRRDDGDSDAAAAAAAPLQDAELALAGINMLLNNGFRESDQLFKQYRNHSPLMSFGASFVSFLNAMMTFEEEKMQLACDDLKTTEKLCESEEAGVIETIKNKIKKNVDVRKSAPSMVDRLQRQIIIADCQVYLAVLSFVKQELSAYIKGGWILRKAWKIYNKCYLDINALQELYQKKLTEESLTSDAANDNHIVAEGVSEESLNRLKGAVSFGYGLFHLCISMVPPNLLKIINLLGFPGDRLQGLSSLMYASESKDMKAPLATLALLWYHTVVRPFFALDGSDNKAGLDEAKEILLKKEAAYPNSSLFMFFKGRIQRLECQINSALTSFHTALELAVDQREIQHVCLYEIGWCSMIELNFKDAFDSFERLKNESRWSQCYYAYLTAVCQGATGDVDGAQIVFKEVQKLFKRKNNQIEQFSVKKAERFRKQTPTKALCVLASIEVLYLWKALPNCSFPNLQRMSQACHEVDDSSVVGLKYLLLGAIHKCLGNSEDAVQYFQRAVKDELCRQNNLYVQPYACYELGCLLLDKPETVGRGRALLLQAKEDFSGYDFENRLHVRIHAALASLRELVPQ", "length": 583 }, "evidence": [ { "id": "SGD:S000003618", "url": "https://alliancegenome.org/gene/SGD:S000003618#orthology", "database": "AGR" }, { "id": "SGD:S000001726", "url": "https://alliancegenome.org/gene/SGD:S000001726#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VE09-1", "protein_name": "Tetratricopeptide repeat protein 39C", "gene_name": "Ttc39c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGSEEQWPRRREDGDPDAAAAPLQDAELALAGINMLLNNGFRESDQLFKQYRNHSPLMSFGASFVSFLNAMMTFEEEKMQLACDDLKTTEKLCESEEAGVIETIKNKIKKNVDARKSTPSMVDRLQRQIIIADCQVYLAVLSFVKQELSAYIKGGWILRKAWKIYSKCYVDINALQELYQKKLTEEPLASDAANDNHVVAEGVTEESLSRLKGAVSFGYGLFHLCISMVPPNLLKIINLLGFPGDRLQGLSSLTYASESKDMKAPLATLALLWYHTVVRPFFALDGSDNKGGLDEAKAILLRKESAYPNSSLFMFFKGRIQRLECQINSALTSFHTALELAVDQREIQHVCLYEIGWCSMIELNFKDAFDSFERLKNESRWSQCYYAYLTAVCQGATGDVDGAQLVFKEVQKLFKRKNNQIEQFSVKKAERFRKQTPTRALCVLASIEVLYLWKALPNCSFPNLQRMSQACHEVDDSSVVGLKHLLLGAIHKCLGNSQDALQFFQRAARDELCRQSNSYVPPYACYELGCLLLDSAETVGRGRTLLLQAKEDFSGYDFENRLHVRIHAALASLRELVPQ", "length": 580 }, "evidence": [ { "id": "SGD:S000003618", "url": "https://alliancegenome.org/gene/SGD:S000003618#orthology", "database": "AGR" }, { "id": "SGD:S000001726", "url": "https://alliancegenome.org/gene/SGD:S000001726#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 187, "end_pos": 189 }, { "start_pos": 38, "end_pos": 40 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"gene_names": [ { "name": "cfap299", "type": "recommended", "evidence": [ { "id": "A2AVJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2AVJ0" } ] }, { "name": "si:ch211-57h10.1", "type": "synonym", "evidence": [ { "id": "A2AVJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2AVJ0" } ] } ], "protein_names": [ { "name": "Cilia- and flagella-associated protein 299", "type": "recommended", "evidence": [ { "id": "A2AVJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2AVJ0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "May be involved in spermatogenesis.", "evidence": [ { "database": "UniProtKB", "id": "A2AVJ0", "url": "https://www.uniprot.org/uniprotkb/A2AVJ0#function" }, { "database": "UniProtKB", "id": "Q810M1", "url": "https://www.uniprot.org/uniprotkb/Q810M1#function" }, { "database": "UniProtKB", "id": "A0AC58JJB2", "url": "https://www.uniprot.org/uniprotkb/A0AC58JJB2#function" }, { "database": "UniProtKB", "id": "ARBA00003056", "url": "https://www.uniprot.org/uniprotkb/ARBA00003056#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2AVJ0", "url": "https://www.uniprot.org/uniprotkb/A2AVJ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cfap299", "url": "https://www.uniprot.org/uniprotkb/A2AVJ0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-173", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-173", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A2AVJ0", "url": "https://alphafold.ebi.ac.uk/entry/A2AVJ0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000088753", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000088753", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "558475", "url": "https://www.ncbi.nlm.nih.gov/gene/558475", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027887", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027887", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558475", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558475", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FNNYQEY", "url": "https://omabrowser.org/oma/group/FNNYQEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2AVJ0", "url": "https://www.orthodb.org/?gene=A2AVJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33588", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33588", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33588:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33588:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14713", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14713", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A2AVJ0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A2AVJ0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "A0AC58JJB2", "url": "https://www.uniprot.org/uniprotkb/A0AC58JJB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JJB2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JJB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AVJ0", "url": "https://www.uniprot.org/uniprotkb/A2AVJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2AVJ0-1", "url": "https://www.uniprot.org/uniprotkb/A2AVJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-173", "url": "https://zfin.org/ZDB-GENE-060526-173", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDNGKGVFSGEKMDEFRTYEDFLDSQIKPVDLFYLEDQELARQLVELGLKDSSLEREEFETRKAAAEASRLASGSQQKKLASTGKELKDNFLRALAEREEANRSGEMNSIIFIRDQNARGQEISAYIDYSHRLKSEDFEPYFSGKKRLLPKTSDLSFYNWRTQKSKHNNSSNYEVITENPSGLLFKCKNDRKILNVDPEKLPGDSSTRTPVQSDLYVHVVIYDHVIRKPTTRSCTPLSN", "length": 239, "header": "sp|A2AVJ0-1|CF299_DANRE Isoform 1 of Cilia- and flagella-associated protein 299 OS=Danio rerio OX=7955 GN=cfap299 PE=3 SV=1 CANONICAL=A2AVJ0-1" }, "isoforms": [ { "isoform_ac": "A0AC58JJB2-1", "url": "https://www.uniprot.org/uniprotkb/A2AVJ0/entry#A0AC58JJB2-1", "sequence": { "sequence": "MDNGKGVFSGEKMDEFRTYEDFLDSQIKPVDLFYLEDQELARQLVELGLKDSSLEREEFETRKAAAEASRLASGSQQKKLASTGKELKDNFLRALAEREEANRSGEMNVINNSSLRHSFCPSP", "length": 123, "header": "tr|A0AC58JJB2-1|A0AC58JJB2_DANRE Computationally mapped isoform of Cilia- and flagella-associated protein 299 OS=Danio rerio OX=7955 GN=cfap299 PE=4 SV=1 CANONICAL=A2AVJ0-1" }, "locus": {} }, { "isoform_ac": "A2AVJ0-1", "url": "https://www.uniprot.org/uniprotkb/A2AVJ0/entry#A2AVJ0-1", "sequence": { "sequence": "MDNGKGVFSGEKMDEFRTYEDFLDSQIKPVDLFYLEDQELARQLVELGLKDSSLEREEFETRKAAAEASRLASGSQQKKLASTGKELKDNFLRALAEREEANRSGEMNSIIFIRDQNARGQEISAYIDYSHRLKSEDFEPYFSGKKRLLPKTSDLSFYNWRTQKSKHNNSSNYEVITENPSGLLFKCKNDRKILNVDPEKLPGDSSTRTPVQSDLYVHVVIYDHVIRKPTTRSCTPLSN", "length": 239, "header": "sp|A2AVJ0-1|CF299_DANRE Isoform 1 of Cilia- and flagella-associated protein 299 OS=Danio rerio OX=7955 GN=cfap299 PE=3 SV=1 CANONICAL=A2AVJ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "A2AVJ0", "url": "https://www.uniprot.org/uniprotkb/A2AVJ0" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:558475", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558475", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LAX3-1", "protein_name": "Cilia- and flagella-associated protein 299", "gene_name": "Cfap299", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDQDDGMTALDNIVTQFNTYEDFLDSQITTVDLYYLEDEGLARQLVELGYRGTGEIVKREDFEARKAAIDIARQAERTQKKTLTSAGKDLHDNFLKALAMREEDNRTGKLSTVIFIRDKNSHGQEVSGYIDYAHRLKSEDFEVYFNGKRRLLPRTTDMSFYNWDSHIAVCNSSPNYQVIADNPEGLLFKYKRDRKILNVDPKAHPGDNSTRIPIQTDLYTHAVLFDHVSRRKT", "length": 233 }, "evidence": [ { "id": "RGD:1597725", "url": "https://alliancegenome.org/gene/RGD:1597725#orthology", "database": "AGR" }, { "id": "MGI:1916571", "url": "https://alliancegenome.org/gene/MGI:1916571#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-173", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-173#orthology", "database": "AGR" }, { "id": "HGNC:28554", "url": "https://alliancegenome.org/gene/HGNC:28554#orthology", "database": "AGR" }, { "id": "FB:FBgn0031720", "url": "https://alliancegenome.org/gene/FB:FBgn0031720#orthology", "database": "AGR" }, { "id": "FB:FBgn0031430", "url": "https://alliancegenome.org/gene/FB:FBgn0031430#orthology", "database": "AGR" }, { "id": "FB:FBgn0031721", "url": "https://alliancegenome.org/gene/FB:FBgn0031721#orthology", "database": "AGR" }, { "id": "FB:FBgn0038122", "url": "https://alliancegenome.org/gene/FB:FBgn0038122#orthology", "database": "AGR" }, { "id": "A2AVJ0", "url": "https://omabrowser.org/oma/group/A2AVJ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2YDG2-1", "protein_name": "Cilia- and flagella-associated protein 299", "gene_name": "CFAP299", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDQDEALTTVDNIVTQFNTYEDFLDSQITTLDLYYLEDEGLARQLVELGYRGTGEVVKREDFEARKAAIEIARLAERTQKKTLTSAGKDLHDNFLKALAVREEDNRSGKSVIFIRDKNSHGQEVSGYIDYAHRLKTEDFEVYFSGKKRLLPRPTDMSFYNWDSHIAIWNSTPNYQVIADNPEGLLFKYKRDRKILNVDPKAQPGDNSTRSPILTELYTQVVIFDHVSRRKT", "length": 231 }, "evidence": [ { "id": "A2AVJ0", "url": "https://omabrowser.org/oma/group/A2AVJ0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6V702-2", "protein_name": "Cilia- and flagella-associated protein 299", "gene_name": "CFAP299", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDQEEGLKALDNIVTQFNAYEDFLDSQITTVDLYYLEDETLARQLVELGYRGTGERVKREDFEARKAAIEIARLAERAQQKTLTSAGKDLQDNFLTALAMREEDNRSGKLSSVIFIRDRNSHGQEISGYIDYAHRLKTEDFEVYFTGKKRLLPRPTDISFYNWDADIAVSNSSPNYQVIADNPEGLLFRYKRDRKILNVDPKAQPGDNSTRITILTELYVQAVIFDHISRRKT", "length": 233 }, "evidence": [ { "id": "RGD:1597725", "url": "https://alliancegenome.org/gene/RGD:1597725#orthology", "database": "AGR" }, { "id": "MGI:1916571", "url": "https://alliancegenome.org/gene/MGI:1916571#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-173", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-173#orthology", "database": "AGR" }, { "id": "HGNC:28554", "url": "https://alliancegenome.org/gene/HGNC:28554#orthology", "database": "AGR" }, { "id": "FB:FBgn0031720", "url": "https://alliancegenome.org/gene/FB:FBgn0031720#orthology", "database": "AGR" }, { "id": "FB:FBgn0031430", "url": "https://alliancegenome.org/gene/FB:FBgn0031430#orthology", "database": "AGR" }, { "id": "FB:FBgn0031721", "url": "https://alliancegenome.org/gene/FB:FBgn0031721#orthology", "database": "AGR" }, { "id": "FB:FBgn0038122", "url": "https://alliancegenome.org/gene/FB:FBgn0038122#orthology", "database": "AGR" }, { "id": "A2AVJ0", "url": "https://omabrowser.org/oma/group/A2AVJ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q810M1-1", "protein_name": "Cilia- and flagella-associated protein 299", "gene_name": "Cfap299", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDQDEGLTAVDNIVTQFNTYEDFLDSQITTVDLYYLEDESLARQLVELGYRGTGEIVKREDFEARKAAINIARQAERTQKKTLTSAGKELHDDFLKALAMREEDNRAGKLSTVIFIRDRNPHGQEVSGYIDYAHRLKSEDFEVYFNGKRRLLPRTTDMSFYNWDSHIAVCNSSPNYQVIADNPEGLLFKYKRDRKILNVDPKAHPGDNSTRIPIQTDLYAHVVLFDHVSRRKT", "length": 233 }, "evidence": [ { "id": "RGD:1597725", "url": "https://alliancegenome.org/gene/RGD:1597725#orthology", "database": "AGR" }, { "id": "MGI:1916571", "url": "https://alliancegenome.org/gene/MGI:1916571#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-173", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-173#orthology", "database": "AGR" }, { "id": "HGNC:28554", "url": "https://alliancegenome.org/gene/HGNC:28554#orthology", "database": "AGR" }, { "id": "FB:FBgn0031720", "url": "https://alliancegenome.org/gene/FB:FBgn0031720#orthology", "database": "AGR" }, { "id": "FB:FBgn0031430", "url": "https://alliancegenome.org/gene/FB:FBgn0031430#orthology", "database": "AGR" }, { "id": "FB:FBgn0031721", "url": "https://alliancegenome.org/gene/FB:FBgn0031721#orthology", "database": "AGR" }, { "id": "FB:FBgn0038122", "url": "https://alliancegenome.org/gene/FB:FBgn0038122#orthology", "database": "AGR" }, { "id": "A2AVJ0", "url": "https://omabrowser.org/oma/group/A2AVJ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VFY6-1", "protein_name": "Cilia- and flagella-associated protein 299", "gene_name": "Cfap299", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTDFSIAKFNNYQEYLHSFTTVEDFRYLPFHKTVITLTKLGYREHRTFYEEDEFLNVKKQVEQLLNPTVSAQIYYSQYFKGTDPALWALAEREHGNVQQEISTIIFLEISGRSGFSKSGYIDFEASLRNYRFKGPNAVDWKAVFEERKLLKPQPSDIVFYDWKTRKIFANDNDNYTVVAHPEHGLMFAHKGDHKNIPVTTKKNPFSSNVRRSMIRSNLYGFIILYDHHVRKKT", "length": 233 }, "evidence": [ { "id": "RGD:1597725", "url": "https://alliancegenome.org/gene/RGD:1597725#orthology", "database": "AGR" }, { "id": "MGI:1916571", "url": "https://alliancegenome.org/gene/MGI:1916571#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-173", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-173#orthology", "database": "AGR" }, { "id": "HGNC:28554", "url": "https://alliancegenome.org/gene/HGNC:28554#orthology", "database": "AGR" }, { "id": "FB:FBgn0038122", "url": "https://alliancegenome.org/gene/FB:FBgn0038122#orthology", "database": "AGR" }, { "id": "A2AVJ0", "url": "https://omabrowser.org/oma/group/A2AVJ0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VMP5-1", "protein_name": "Cilia- and flagella-associated protein 299", "gene_name": "Dmel\\CG14017", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEDSQRKHAGSKGFRALENRKQDIAYNHYLNSFVKLEDRRYLPNDNVIHQLVPLRAAVGTIVMTPTQFNEVHFSPLGTCFYFSENNVPNDPLTMALLEREKLNATKTISTIVFVSTRDSKGFNISGYIDLEHSLRRYKTAGSKSHPWADIFAGRRRLEPNHQDLSFINWSNGRVHSNDSDNYKVIPDAVKGLCFAHKGDGSMLSIEKYITEEHPLCKFIESPKHGYTVVYDHYIRRKM", "length": 238 }, "evidence": [ { "id": "RGD:1597725", "url": "https://alliancegenome.org/gene/RGD:1597725#orthology", "database": "AGR" }, { "id": "MGI:1916571", "url": "https://alliancegenome.org/gene/MGI:1916571#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-173", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-173#orthology", "database": "AGR" }, { "id": "HGNC:28554", "url": "https://alliancegenome.org/gene/HGNC:28554#orthology", "database": "AGR" }, { "id": "FB:FBgn0031721", "url": "https://alliancegenome.org/gene/FB:FBgn0031721#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VMP6-1", "protein_name": "Cilia- and flagella-associated protein 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"NP_001098587", "name": "uncharacterized protein LOC565274", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001098587" }, "gene_names": [ { "name": "tm4sf21a", "type": "recommended", "evidence": [ { "id": "A2BEN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BEN8" } ] }, { "name": "si:ch211-137i24.10", "type": "synonym", "evidence": [ { "id": "NP_001098587", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001098587" }, { "id": "A2BEN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BEN8" } ] }, { "name": "tm4sf21a", "type": "synonym", "evidence": [ { "id": "NP_001098587", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001098587" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC565274", "type": "synonym", "evidence": [ { "id": "A2BEN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BEN8/entry#names_and_taxonomy" } ] }, { "name": "tm4sf4", "type": "synonym", "evidence": [ { "id": "NP_001098587", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001098587" } ] }, { "name": "uncharacterized protein LOC565274", "type": "synonym", "evidence": [ { "id": "NP_001098587", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001098587" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC115191.1, GFIL01035528.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505377 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000005.1. On Sep 20, 2007 this sequence version replaced XP_693646.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001098587", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001098587" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BEN8", "url": "https://www.uniprot.org/uniprotkb/A2BEN8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tm4sf21a", "url": "https://www.uniprot.org/uniprotkb/A2BEN8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-34", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-34", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000057706", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000057706", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "565274", "url": "https://www.ncbi.nlm.nih.gov/gene/565274", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008661", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008661", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565274", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565274", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CASQMIN", "url": "https://omabrowser.org/oma/group/CASQMIN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2BEN8", "url": "https://www.orthodb.org/?gene=A2BEN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14198:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14198:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001098587", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001098587", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2BEN8", "url": "https://www.uniprot.org/uniprotkb/A2BEN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BEN8-1", "url": "https://www.uniprot.org/uniprotkb/A2BEN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-34", "url": "https://zfin.org/ZDB-GENE-060526-34", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MCTGKCAFCVGTSLYPLAVISIICNIILFFPGWDVKYSQNGQLTEEVKYMGGLVGGGVMVLIPAFHIHLTGKQGCCANRCGMFLSILFAAVGVVGALYSFIVALMGLINGPYCLSSFSWTTPFKDRNESYLKDRDSWKDCTEPKNVVEFNVGLFSTLLVTSAVQLVLCAVQMINGLFGCLCGTCKKDKGPL", "length": 191, "header": "tr|A2BEN8-1|A2BEN8_DANRE Isoform 1 of Uncharacterized protein LOC565274 OS=Danio rerio OX=7955 GN=tm4sf21a PE=3 SV=1 CANONICAL=A2BEN8-1" }, "isoforms": [ { "isoform_ac": "A2BEN8-1", "url": "https://www.uniprot.org/uniprotkb/A2BEN8/entry#A2BEN8-1", "sequence": { "sequence": "MCTGKCAFCVGTSLYPLAVISIICNIILFFPGWDVKYSQNGQLTEEVKYMGGLVGGGVMVLIPAFHIHLTGKQGCCANRCGMFLSILFAAVGVVGALYSFIVALMGLINGPYCLSSFSWTTPFKDRNESYLKDRDSWKDCTEPKNVVEFNVGLFSTLLVTSAVQLVLCAVQMINGLFGCLCGTCKKDKGPL", "length": 191, "header": "tr|A2BEN8-1|A2BEN8_DANRE Isoform 1 of Uncharacterized protein LOC565274 OS=Danio rerio OX=7955 GN=tm4sf21a PE=3 SV=1 CANONICAL=A2BEN8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "FACS-assisted microarray profiling implicates novel genes and pathways in zebrafish gastrointestinal tract development.", "journal": "Gastroenterology", "date": "2009", "authors": "Stuckenholz Carsten, Lu Lili, Thakur Prakash, Kaminski Naftali, Bahary Nathan", "evidence": [ { "database": "UniProtKB", "id": "A2BEN8", "url": "https://www.uniprot.org/uniprotkb/A2BEN8" } ], "reference": [ { "type": "PubMed", "id": "19563808", "url": "https://glygen.org/publication/PubMed/19563808" } ] }, { "title": "Genome-wide identification of molecular pathways and biomarkers in response to arsenic exposure in zebrafish liver.", "journal": "PLoS ONE", "date": "2013", "authors": "Xu Hongyan, Lam Siew Hong, Shen Yuan, Gong Zhiyuan", "evidence": [ { "database": "UniProtKB", "id": "A2BEN8", "url": "https://www.uniprot.org/uniprotkb/A2BEN8" } ], "reference": [ { "type": "PubMed", "id": "23922661", "url": "https://glygen.org/publication/PubMed/23922661" } ] } ], "pathway": [ { "id": "dre:565274", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565274", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2BF97-1", "uniprot_ac": "A2BF97", "uniprot_id": "A2BF97_DANRE", "mass": { "chemical_mass": 33072.0, "monoisotopic_mass": 33072.0 }, "refseq": { "ac": "NP_001313325", "name": "protein limb expression 1 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313325" }, "gene_names": [ { "name": "lix1", "type": "recommended", "evidence": [ { "id": "A2BF97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BF97" } ] }, { "name": "lix1", "type": "synonym", "evidence": [ { "id": "NP_001313325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313325" } ] }, { "name": "si:ch211-236k19.8", "type": "synonym", "evidence": [ { "id": "NP_001313325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313325" }, { "id": "A2BF97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BF97" } ] } ], "protein_names": [ { "name": "Lix1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001313325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313325" } ] }, { "name": "Protein limb expression 1 homolog", "type": "synonym", "evidence": [ { "id": "A2BF97", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BF97/entry#names_and_taxonomy" } ] }, { "name": "protein limb expression 1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001313325", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313325" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH593115.1, CT653017.2 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505387, SAMEA4476729 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On May 17, 2016 this sequence version replaced XP_686266.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001313325", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313325" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BF97", "url": "https://www.uniprot.org/uniprotkb/A2BF97" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "lix1", "url": "https://www.uniprot.org/uniprotkb/A2BF97", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-123", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-123", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000052154", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000052154", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "558010", "url": "https://www.ncbi.nlm.nih.gov/gene/558010", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029270", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029270", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558010", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558010", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMLQEFW", "url": "https://omabrowser.org/oma/group/AMLQEFW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2BF97", "url": "https://www.orthodb.org/?gene=A2BF97", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31139", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31139", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31139:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31139:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14954", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14954", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001313325", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313325", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58JJB3", "url": "https://www.uniprot.org/uniprotkb/A0AC58JJB3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JJB3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JJB3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BF97", "url": "https://www.uniprot.org/uniprotkb/A2BF97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BF97-1", "url": "https://www.uniprot.org/uniprotkb/A2BF97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-123", "url": "https://zfin.org/ZDB-GENE-060526-123", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSGADSDDDRAFKDLNVVGMLHKFWEQKQAAGVMMEIENLVVYESIPSPSPPFICYVTLPGGSCFGNFKHCYSKAEARRDAARVALMNSTFNELPCRRITPEFISHSVKEAVSTTSGNIADASDPSTSIGAYCLMLELNTGKTMLEFQEIMTVFQLLHWNGTLKAFRDMRCSRQEVIQYYSQQRLDERTRSHMALDWLQKELQSPGLLSQELQLAVKELGEARRTGRELRFYKEKKEILSLALSHADAEDLEEEMSWREATEFDCFEERRTDTNESCQFHSQGSDGESLE", "length": 290, "header": "tr|A2BF97-1|A2BF97_DANRE Isoform 1 of Protein limb expression 1 homolog OS=Danio rerio OX=7955 GN=lix1 PE=3 SV=1 CANONICAL=A2BF97-1" }, "isoforms": [ { "isoform_ac": "A0AC58JJB3-1", "url": "https://www.uniprot.org/uniprotkb/A2BF97/entry#A0AC58JJB3-1", "sequence": { "sequence": "MLELNTGKTMLEFQEIMTVFQLLHWNGTLKAFRDMRCSRQEVIQYYSQQRLDERTRSHMALDWLQKELQSPGLLSQELQLAVKELGEARRTGRELRFYKEKKEILSLALSHADAEDLEEEMSWREATEFDCFEERRTDTNESCQFHSQGSDGESLE", "length": 156, "header": "tr|A0AC58JJB3-1|A0AC58JJB3_DANRE Computationally mapped isoform of Protein limb expression 1 homolog isoform X1 OS=Danio rerio OX=7955 GN=lix1 PE=4 SV=1 CANONICAL=A2BF97-1" }, "locus": {} }, { "isoform_ac": "A2BF97-1", "url": "https://www.uniprot.org/uniprotkb/A2BF97/entry#A2BF97-1", "sequence": { "sequence": "MSGADSDDDRAFKDLNVVGMLHKFWEQKQAAGVMMEIENLVVYESIPSPSPPFICYVTLPGGSCFGNFKHCYSKAEARRDAARVALMNSTFNELPCRRITPEFISHSVKEAVSTTSGNIADASDPSTSIGAYCLMLELNTGKTMLEFQEIMTVFQLLHWNGTLKAFRDMRCSRQEVIQYYSQQRLDERTRSHMALDWLQKELQSPGLLSQELQLAVKELGEARRTGRELRFYKEKKEILSLALSHADAEDLEEEMSWREATEFDCFEERRTDTNESCQFHSQGSDGESLE", "length": 290, "header": "tr|A2BF97-1|A2BF97_DANRE Isoform 1 of Protein limb expression 1 homolog OS=Danio rerio OX=7955 GN=lix1 PE=3 SV=1 CANONICAL=A2BF97-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A morpholino-based screen to identify novel genes involved in craniofacial morphogenesis.", "journal": "Dev. Dyn.", "date": "2013", "authors": "Melvin Vida Senkus, Feng Weiguo, Hernandez-Lagunas Laura, Artinger Kristin Bruk, Williams Trevor", "evidence": [ { "database": "UniProtKB", "id": "A2BF97", "url": "https://www.uniprot.org/uniprotkb/A2BF97" } ], "reference": [ { "type": "PubMed", "id": "23559552", "url": "https://glygen.org/publication/PubMed/23559552" } ] }, { "title": "New classes of mind bomb-interacting proteins identified from yeast two-hybrid screens.", "journal": "PLoS ONE", "date": "2014", "authors": "Tseng Li-Chuan, Zhang Chengjin, Cheng Chun-Mei, Xu Haoying, Hsu Chia-Hao, Jiang Yun-Jin", "evidence": [ { "database": "UniProtKB", "id": "A2BF97", "url": "https://www.uniprot.org/uniprotkb/A2BF97" } ], "reference": [ { "type": "PubMed", "id": "24714733", "url": "https://glygen.org/publication/PubMed/24714733" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A2BF97", "url": "https://www.uniprot.org/uniprotkb/A2BF97" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:558010", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558010", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZAG6-1", "protein_name": "Limb and CNS expressed 1", "gene_name": "Lix1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRTLESLRHIIAQALPHRDPALVFKDLNVVSMLQEFWESKQQQRATFSSEGLVVYESMPSSGPPFVSYVTLPGGSCFGNFQCCLSRAEARRDAAKVALINSLFNELPSRRITKEFIMESVQEAVASTRGTLDDADDPSTSVGAYHYMLESNMGKTMLEFQELMTIFQLLHWNGSLKALRETKCSRQEVISYYSQYSLDEKMRSHMALDWIMKERESPGILSQELRAALGQLEEARKAGQELRFYKEKKEILSLALTQIYCDPDPSSPSDDQLSLTALCGYH", "length": 282 }, "evidence": [ { "id": "HGNC:18581", "url": "https://alliancegenome.org/gene/HGNC:18581#orthology", "database": "AGR" }, { "id": "MGI:1913893", "url": "https://alliancegenome.org/gene/MGI:1913893#orthology", "database": "AGR" }, { "id": "A2BF97", "url": "https://omabrowser.org/oma/group/A2BF97/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P566-1", "protein_name": "Protein limb expression 1 homolog", "gene_name": "Lix1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDRTLESLRHIIAQALPHRDPALVFKDLNVVSMLQEFWESKQQQKATFSSEGLVVYESMPSSGPPFVSYVTLPGGSCFGNFQCCLSRAEARRDAAKVALINSLFNELPSRRITKEFIMESVQEAVASTRGTLDDADDPSTSVGAYHYMLESNMGKTMLEFQELMTIFQLLHWNGSLKALRETKCSRQEVISYYSQYSLDEKMRSHMALDWIMKERESPGILSQELRAALGQLEEARKAGQELRFYKEKKEILSLALTQIYSDPDPSSPSDDQLSLTALCGYH", "length": 282 }, "evidence": [ { "id": "HGNC:18581", "url": "https://alliancegenome.org/gene/HGNC:18581#orthology", "database": "AGR" }, { "id": "MGI:1913893", "url": "https://alliancegenome.org/gene/MGI:1913893#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-123", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-123#orthology", "database": "AGR" }, { "id": "A2BF97", "url": "https://omabrowser.org/oma/group/A2BF97/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N485-1", "protein_name": "Protein limb expression 1 homolog", "gene_name": "LIX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDRTLESLRHIIAQVLPHRDPALVFKDLNVVSMLQEFWESKQQQKAAFPSEGVVVYESLPAPGPPFVSYVTLPGGSCFGNFQCCLSRAEARRDAAKVALINSLFNELPSRRITKEFIMESVQEAVASTSGTLDDADDPSTSVGAYHYMLESNMGKTMLEFQELMTIFQLLHWNGSLKALRETKCSRQEVISYYSQYSLDEKMRSHMALDWIMKERDSPGIVSQELRMALRQLEEARKAGQELRFYKEKKEILSLALTQICSDPDTSSPSDDQLSLTALCGYH", "length": 282 }, "evidence": [ { "id": "HGNC:18581", "url": "https://alliancegenome.org/gene/HGNC:18581#orthology", "database": "AGR" }, { "id": "MGI:1913893", "url": "https://alliancegenome.org/gene/MGI:1913893#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-123", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-123#orthology", "database": "AGR" }, { "id": "A2BF97", "url": "https://omabrowser.org/oma/group/A2BF97/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8UVV7-1", "protein_name": "Protein limb expression 1", "gene_name": "LIX1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MDRTLESLQLVIARVLPHRDPALVFKDLNVVAILQEFWESKQKKKAVLPSEGIIVYESLSSLGPPFVSYVTLPGGSCFGNFQSCLSRAEARRDAAKVALINSLFNELPCRRITKEFIMESVQEAVSSTSGNLKDADDPSTSIGAYHYMLESNIGKTMLEFQELMIVFQLLHWNGSLKALRETKCSRQEVISYYSQCSLDEKMRSHMALDWIMKEQESPGIISQELQVALRELEEVRKAGHELRFYKEKKEILSLALSQIYSDEVTTSSWDNQMSLALHGYR", "length": 281 }, "evidence": [ { "id": "A2BF97", "url": "https://omabrowser.org/oma/group/A2BF97/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q9VKY1-1", "protein_name": "Protein limb expression 1 homolog", "gene_name": "lft", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVYPEEPFWVLPTVTGFYEDRDYRVNVVEALQEFWQMKQSRGAELKNGALVIYESIPSNSQPYICFVTLPGGSCFGSFQNCPTKAEARRSSAKIALMNSVFNEHPSRRISDEFIQKAVQDARTSFKGTSQINEGTESGIGAFRFMLEANKGRTMLEFQELMTVFQLLHWNGSLKAMRERHCSRQEVVAHYSNRSLDDEMRSQMALDWIAREHDNPGVIRRELVLAERELETFRMAGRELRFPKEKKDILMIAHNQLGGSALNSATIDD", "length": 268 }, "evidence": [ { "id": "HGNC:18581", "url": "https://alliancegenome.org/gene/HGNC:18581#orthology", "database": "AGR" }, { "id": "MGI:1913893", "url": "https://alliancegenome.org/gene/MGI:1913893#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "autophagosome maturation", "id": "GO:0097352", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097352", "evidence": [ { "database": "UniProtKB", "id": "A2BF97", "url": "https://www.uniprot.org/uniprotkb/A2BF97" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2BF97", "url": "https://www.uniprot.org/uniprotkb/A2BF97" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 160, "end_pos": 162 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2BFQ3-1", "uniprot_ac": "A2BFQ3", "uniprot_id": "A2BFQ3_DANRE", "mass": { "chemical_mass": 21203.0, "monoisotopic_mass": 21203.0 }, "refseq": { "ac": "NP_001094424", "name": "uncharacterized protein LOC566993", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094424" }, "gene_names": [ { "name": "si:dkey-111e8.5", "type": "recommended", "evidence": [ { "id": "A2BFQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BFQ3" } ] }, { "name": "si:dkey-111e8.5", "type": "synonym", "evidence": [ { "id": "NP_001094424", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094424" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC566993", "type": "synonym", "evidence": [ { "id": "A2BFQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BFQ3/entry#names_and_taxonomy" } ] }, { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A2BFQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BFQ3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC566993", "type": "synonym", "evidence": [ { "id": "NP_001094424", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094424" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588717.2334830.1, SRR32588732.9813083.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505379, SAMEA3505388 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000005.1. 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Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A2BFQ3", "url": "https://www.uniprot.org/uniprotkb/A2BFQ3" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A2BFQ3", "url": "https://www.uniprot.org/uniprotkb/A2BFQ3" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:566993", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566993", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 145, "end_pos": 147, "annotation": "n_glycosylation_sequon" }, { "start_pos": 96, "end_pos": 98, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": 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has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Feb 21, 2008 this sequence version replaced XP_001337477.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001108163", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108163" } ] } ], "disease": [ { "disease_id": "DOID:0060705", "recommended_name": { "id": "DOID:0060705", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060705", "name": "X-linked lymphoproliferative syndrome 1", "description": "A lymphoproliferative syndrome characterized by severe immune dysregulation after viral infection that may manifest as severe or fatal mononucleosis, acquired hypogammaglobulinema, hemophagocytic lymphohistiocytosis, and/or malignant lymphoma and that has_material_basis_in X-linked mutation in the SH2D1A gene on chromosome Xq25." }, "synonyms": [ { "id": "DOID:0060705", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060705", "name": "XLP1", "description": "" }, { "id": "MONDO:0024551", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024551", "name": "X-linked lymphoproliferative disease due to SH2D1A deficiency", "description": "A rare, genetic, primary immunodeficiency disorder characterized by an abnormal immune response to Epstein-Barr virus (EBV) infection, caused by hemizygous mutations in the X-linked SH2D1A gene, resulting in B cell lymphoproliferation and manifesting with various phenotypes which include EBV-driven severe or fulminant mononucleosis, hemophagocytic lymphohistiocytosis (presenting with fulminant hepatitis, hepatic necrosis, bone marrow hypoplasia, and neurological involvement), hypogammaglobulinemia, and B-cell lymphoma. Additional variable manifestations include vasculitis, lymphomatoid granulomatosis, aplastic anemia, and chronic gastritis. Occasionally, T-cell lymphoma may be observed. Laboratory findings include normal or increased activated T cells and reduced memory B cells." }, { "id": "MONDO:0024551", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024551", "name": "X-linked lymphoproliferative disease due to SH2D1A deficiency", "description": "" }, { "id": "MONDO:0024551", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024551", "name": "lymphoproliferative syndrome, X-linked, 1, X-linked recessive", "description": "" }, { "id": "MONDO:0024551", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024551", "name": "XLP1", "description": "" }, { "id": "MIM:308240", "resource": "MIM", "url": "https://www.omim.org/entry/308240", "name": "Lymphoproliferative syndrome, X-linked, 1", "description": "Lymphoproliferative syndrome, X-linked, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060705", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060705" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BGK3", "url": "https://www.uniprot.org/uniprotkb/A2BGK3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sh2d1aa", "url": "https://www.uniprot.org/uniprotkb/A2BGK3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-212", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-212", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000095348", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000095348", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "797046", "url": "https://www.ncbi.nlm.nih.gov/gene/797046", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:797046", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797046", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHKHINT", "url": "https://omabrowser.org/oma/group/PHKHINT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2BGK3", "url": "https://www.orthodb.org/?gene=A2BGK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46051:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46051:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00017", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00017", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001108163", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108163", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2BGK3", "url": "https://www.uniprot.org/uniprotkb/A2BGK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BGK3-1", "url": "https://www.uniprot.org/uniprotkb/A2BGK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-212", "url": "https://zfin.org/ZDB-GENE-060526-212", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEDLAEYHGSISKKQAEDILCSTGRDGSYLIRDSLSSAGAYCVCVLCDGWVYTYRIFNKGGLWTIEMAPGMKERLFRNVSNLIAAFKMPDQGITFPLLYPVNKPKH", "length": 106, "header": "tr|A2BGK3-1|A2BGK3_DANRE Isoform 1 of SH2 domain containing 1A duplicate a OS=Danio rerio OX=7955 GN=sh2d1aa PE=4 SV=1 CANONICAL=A2BGK3-1" }, "isoforms": [ { "isoform_ac": "A2BGK3-1", "url": "https://www.uniprot.org/uniprotkb/A2BGK3/entry#A2BGK3-1", "sequence": { "sequence": "MEDLAEYHGSISKKQAEDILCSTGRDGSYLIRDSLSSAGAYCVCVLCDGWVYTYRIFNKGGLWTIEMAPGMKERLFRNVSNLIAAFKMPDQGITFPLLYPVNKPKH", "length": 106, "header": "tr|A2BGK3-1|A2BGK3_DANRE Isoform 1 of SH2 domain containing 1A duplicate a OS=Danio rerio OX=7955 GN=sh2d1aa PE=4 SV=1 CANONICAL=A2BGK3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Angiotensin AT2 receptor activates the cyclic-AMP signaling pathway in eel.", "journal": "Mol. 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2BGN0-1", "uniprot_ac": "A2BGN0", "uniprot_id": "A2BGN0_DANRE", "mass": { "chemical_mass": 25898.0, "monoisotopic_mass": 25898.0 }, "refseq": { "ac": "NP_001076278", "name": "corrinoid adenosyltransferase MMAB", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076278" }, "gene_names": [ { "name": "mmab", "type": "recommended", "evidence": [ { "id": "A2BGN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGN0" } ] }, { "name": "mmab", "type": "synonym", "evidence": [ { "id": "NP_001076278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076278" } ] }, { "name": "si:dkey-189p24.5", "type": "synonym", "evidence": [ { "id": "NP_001076278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076278" }, { "id": "A2BGN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGN0" } ] } ], "protein_names": [ { "name": "Corrinoid adenosyltransferase MMAB", "type": "recommended", "evidence": [ { "id": "A2BGN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGN0/entry#names_and_taxonomy" } ] }, { "name": "ATP:co(I)rrinoid adenosyltransferase MMAB", "type": "synonym", "evidence": [ { "id": "A2BGN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGN0/entry#names_and_taxonomy" } ] }, { "name": "corrinoid adenosyltransferase MMAB", "type": "synonym", "evidence": [ { "id": "NP_001076278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076278" } ] }, { "name": "methylmalonic aciduria (cobalamin deficiency) cblB type", "type": "synonym", "evidence": [ { "id": "NP_001076278", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076278" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC133925.1, GFIL01026569.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Mar 15, 2007 this sequence version replaced XP_685149.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001076278", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076278" } ] }, { "annotation": "Converts cob(I)alamin to adenosylcobalamin (adenosylcob(III)alamin), a coenzyme for methylmalonyl-CoA mutase, therefore participates in the final step of the vitamin B12 conversion. 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Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A2BGN0", "url": "https://www.uniprot.org/uniprotkb/A2BGN0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A2BGN0", "url": "https://www.uniprot.org/uniprotkb/A2BGN0" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:557077", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557077", "resource": "KEGG Pathway" }, { "id": "R-DRE-9759218", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9759218", "resource": "Reactome", "description": "Cobalamin (Cbl) metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZLS8-1", "protein_name": "Metabolism of cobalamin associated B", "gene_name": "MMAB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLRRAAAAAAGSGLGRPLWVVAGRGQSGEAGSPEGGPPSARSPRIYTRTGDEGFSSTFTGERRPKGDRIFEALGTTDELSSAIGLASELSSEKGHAFVEQLHKVQCMLQDVGSNIATPLSSAREAHLKRTSFSEEPILELEKWIDRYSEQLPPLRAFILPCGSLSTSRGGRSKRGQIFKQTERLPLRFGTLCCNEGREGRENIYKAKTITGSWDVYAVDLGKLNPAERFSRHGWQREQAQIGNVSCQRLPVNMMGTLFINAVRNTAVLSTRPCSDTVVLVSELLFALDQS", "length": 290 }, "evidence": [ { "id": "A2BGN0", "url": "https://omabrowser.org/oma/group/A2BGN0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7FZ58-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "Mmab", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVWVFGGRLGLRRHLDVCRLLCPRFQSRGPQSEEDGNRPKSSSKAHKIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFAMELITEKGHTFAKELQKIQCTLQDVGSALATPRSSAREAHLKYTTFKEGPIVELEQWIDKYSSQLPPLTAFILPSGGKSSSALHFCRAVCRRAERRLEADSPAHEGTKTTLVGTKASLPSAYLLCLLLHWPGHVMSVQVWCLLSKWEKRMQMWPSF", "length": 249 }, "evidence": [ { "id": "A2BGN0", "url": "https://omabrowser.org/oma/group/A2BGN0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0L5G5-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "Mmab", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVWTFGGRLGLRGRLGGCRLLCPRFQSFGPQGGEDGDRPQPSSKAAKVLKIYTKTGDKGLSSTFTGERRPKDDQVFEALGTTDELSSAIGFAMELITEKGHTFAEELRKIQCTLQDVGSALATPRSSAREAHLKHTAFQEEPILELEQWIDKYSSQLPPLTAFILPSGGKSSSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNSSGRAEPGAGATCRLLGWRSSPGLSDYLFTVARYAAMKEGSQEKIYKKRDV", "length": 259 }, "evidence": [ { "id": "MGI:1924947", "url": "https://alliancegenome.org/gene/MGI:1924947#orthology", "database": "AGR" }, { "id": "HGNC:19331", "url": "https://alliancegenome.org/gene/HGNC:19331#orthology", "database": "AGR" }, { "id": "A2BGN0", "url": "https://omabrowser.org/oma/group/A2BGN0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q54W51-1", "protein_name": "Cobalamin adenosyltransferase-like domain-containing protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNKLIKISNFRNNNNNNILIINRFFSSKIYTKTGDKGTSALFNGERRKKDDQIFQALGSVDELSSQLGLSKEHLIVLRKEINNEKKELANRVIDEIEQIQCLLLDIGSHIATPSYSEEQFQKRSQFNDFHTTQLENWVDHYTNNHLAPLKNFILPGGGLTSASLHVCRSVCRRSERELITMTNLENEYENNNNNNNNNNNNNNNNNNNEISSPVLRFINRLSDYLFTIARISNKIEGGEESIYRRPSESLSSNNKNNNNSNSSNNNNNNNNNNNDNNKYQRILEKHSTIQD", "length": 291 }, "evidence": [ { "id": "A2BGN0", "url": "https://omabrowser.org/oma/group/A2BGN0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q96EY8-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "MMAB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVCGLGSRLGLGSRLGLRGCFGAARLLYPRFQSRGPQGVEDGDRPQPSSKTPRIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFALELVTEKGHTFAEELQKIQCTLQDVGSALATPCSSAREAHLKYTTFKAGPILELEQWIDKYTSQLPPLTAFILPSGGKISSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTLARYAAMKEGNQEKIYMKNDPSAESEGL", "length": 250 }, "evidence": [ { "id": "MGI:1924947", "url": "https://alliancegenome.org/gene/MGI:1924947#orthology", "database": "AGR" }, { "id": "HGNC:19331", "url": "https://alliancegenome.org/gene/HGNC:19331#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-232", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-232#orthology", "database": "AGR" }, { "id": "A2BGN0", "url": "https://omabrowser.org/oma/group/A2BGN0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D273-1", "protein_name": "Corrinoid adenosyltransferase MMAB", "gene_name": "Mmab", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVWLFGGRLGLRGRLSACRLLCPRFQSRGPQGGEDGDRLQPSSTAAKIPKIYTKTGDKGFSSTFTGERRPKDDQVFEAVGTTDELSSAIGFAMELVTEKGHMFAEELQKIQCMLQDVGSALATPRSSAREAHLKHTAFQEGPVLELERWIDKYSSQLPPLKAFILPSGGKSSSALHFCRAVCRRAERRVVPLVQMGETDANVAKFLNRLSDYLFTVARYAAMKEGSQEKIYKKHDV", "length": 237 }, "evidence": [ { "id": "MGI:1924947", "url": "https://alliancegenome.org/gene/MGI:1924947#orthology", "database": "AGR" }, { "id": "HGNC:19331", "url": "https://alliancegenome.org/gene/HGNC:19331#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-232", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-232#orthology", "database": "AGR" }, { "id": "A2BGN0", "url": "https://omabrowser.org/oma/group/A2BGN0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A2BGN0", "url": "https://www.uniprot.org/uniprotkb/A2BGN0" } ], "pmid": "" }, { "name": "corrinoid adenosyltransferase activity", "id": "GO:0008817", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008817", "evidence": [ { "database": "UniProtKB", "id": "A2BGN0", "url": "https://www.uniprot.org/uniprotkb/A2BGN0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cobalamin metabolic process", "id": "GO:0009235", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009235", "evidence": [ { "database": "UniProtKB", "id": "A2BGN0", "url": "https://www.uniprot.org/uniprotkb/A2BGN0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "56796", "name": "", "equation": "cob(I)alamin-[corrinoid adenosyltransferase] + ATP = apo-[corrinoid adenosyltransferase] + adenosylcob(III)alamin + triphosphate", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [], "evidence": [ { "id": "56796", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/56796" } ] } ], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A2BGN0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGN0" }, { "id": "PF01923", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cobalamin adenosyltransferase-like", "eco_id": "ECO_0000259", "start_pos": 49, "end_pos": 218, "start_aa": "Ile", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2BGQ2-1", "uniprot_ac": "A2BGQ2", "uniprot_id": "A2BGQ2_DANRE", "mass": { "chemical_mass": 69342.0, "monoisotopic_mass": 69342.0 }, "refseq": { "ac": "NP_001091661", "name": "uncharacterized protein LOC100000539", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001091661" }, "gene_names": [ { "name": "si:ch211-214j8.12", "type": "recommended", "evidence": [ { "id": "A2BGQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGQ2" } ] }, { "name": "si:ch211-214j8.12", "type": "synonym", "evidence": [ { "id": "NP_001091661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001091661" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100000539", "type": "synonym", "evidence": [ { "id": "A2BGQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGQ2/entry#names_and_taxonomy" } ] }, { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A2BGQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGQ2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100000539", "type": "synonym", "evidence": [ { "id": "NP_001091661", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001091661" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.10139065.1, SRR32588725.23272993.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476788, SAMN02418766 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000005.1. On May 24, 2007 this sequence version replaced XP_001340720.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001091661", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001091661" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BGQ2", "url": "https://www.uniprot.org/uniprotkb/A2BGQ2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-214j8.12", "url": "https://www.uniprot.org/uniprotkb/A2BGQ2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-102", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-102", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092556", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092556", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100000539", "url": "https://www.ncbi.nlm.nih.gov/gene/100000539", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100000539", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000539", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DYADNYM", "url": "https://omabrowser.org/oma/group/DYADNYM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2BGQ2", "url": "https://www.orthodb.org/?gene=A2BGQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38926", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38926", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38926:SF72", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38926:SF72", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001091661", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001091661", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2BGQ2", "url": "https://www.uniprot.org/uniprotkb/A2BGQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BGQ2-1", "url": "https://www.uniprot.org/uniprotkb/A2BGQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-102", "url": "https://zfin.org/ZDB-GENE-060526-102", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPLFRQLEPTPERKSQRKKKHWTEDEEKPSTLIGLCLQSLAENMKELWAKDYAQKYMDQYFFRYIMGPFSLLPGELLEELLCILSSRNLLTRAALHLLLLPQLSSLSLASACSLVNASLCSLIQIRCQNLQSLDLSGSQNISASVLCELLGSQHRLRSLSLAGTLCDQKVMSVLSLQCPKLKHLDVSRCLHLTPAGLLPLAYREAHVNSTNTISSLLALDIGLAENEGDAVSAVAFLLLSLPGLQRLAVEGLGQACVLILNREFEGTEEFTSREGVQCLKDLWAKKTLDGRSSMSANGEERFTLEGKLDECLSLDESESRVNEWTGTSKECDEKVRSHIVSDNVTTCLKDVQGLSLDTLEAVGKVCPELRVLSLDCLQNIVNADSFEHGAVLARGLGRFSGQLNSLSLQFAGFLSDLVPALQAAGSNLLSLSLEGIKADGHTAFLELIRACPRLTSLSIHLDPPNSNMDEDDEDEDAEDEGRLSNLPCIPHLRSLTLHFSLDERQMKPPLCWTSLKDVLWALLRGASLLQKLSLIAVPCRLDPVFKLVLNHPAKPLDALDNPPLQCLRSASLNRSDITMDTVVHVVNTCRRLSCLDLSGCWEMSLSNITKLQSKTKRRRHTLQITWT", "length": 627, "header": "tr|A2BGQ2-1|A2BGQ2_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-214j8.12 PE=1 SV=1 CANONICAL=A2BGQ2-1" }, "isoforms": [ { "isoform_ac": "A2BGQ2-1", "url": "https://www.uniprot.org/uniprotkb/A2BGQ2/entry#A2BGQ2-1", "sequence": { "sequence": "MPLFRQLEPTPERKSQRKKKHWTEDEEKPSTLIGLCLQSLAENMKELWAKDYAQKYMDQYFFRYIMGPFSLLPGELLEELLCILSSRNLLTRAALHLLLLPQLSSLSLASACSLVNASLCSLIQIRCQNLQSLDLSGSQNISASVLCELLGSQHRLRSLSLAGTLCDQKVMSVLSLQCPKLKHLDVSRCLHLTPAGLLPLAYREAHVNSTNTISSLLALDIGLAENEGDAVSAVAFLLLSLPGLQRLAVEGLGQACVLILNREFEGTEEFTSREGVQCLKDLWAKKTLDGRSSMSANGEERFTLEGKLDECLSLDESESRVNEWTGTSKECDEKVRSHIVSDNVTTCLKDVQGLSLDTLEAVGKVCPELRVLSLDCLQNIVNADSFEHGAVLARGLGRFSGQLNSLSLQFAGFLSDLVPALQAAGSNLLSLSLEGIKADGHTAFLELIRACPRLTSLSIHLDPPNSNMDEDDEDEDAEDEGRLSNLPCIPHLRSLTLHFSLDERQMKPPLCWTSLKDVLWALLRGASLLQKLSLIAVPCRLDPVFKLVLNHPAKPLDALDNPPLQCLRSASLNRSDITMDTVVHVVNTCRRLSCLDLSGCWEMSLSNITKLQSKTKRRRHTLQITWT", "length": 627, "header": "tr|A2BGQ2-1|A2BGQ2_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-214j8.12 PE=1 SV=1 CANONICAL=A2BGQ2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A2BGQ2", "url": "https://www.uniprot.org/uniprotkb/A2BGQ2" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100000539", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000539", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "SCF ubiquitin ligase complex binding", "id": "GO:1905761", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1905761", "evidence": [ { "database": "UniProtKB", "id": "A2BGQ2", "url": "https://www.uniprot.org/uniprotkb/A2BGQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 343, "end_pos": 345, "annotation": "n_glycosylation_sequon" }, { "start_pos": 573, "end_pos": 575, "annotation": "n_glycosylation_sequon" }, { "start_pos": 607, "end_pos": 609, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 140, "end_pos": 142 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 343, "end_pos": 345 }, { "start_pos": 573, "end_pos": 575 }, { "start_pos": 607, "end_pos": 609 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2BGZ3-1", "uniprot_ac": "A2BGZ3", "uniprot_id": "A2BGZ3_DANRE", "mass": { "chemical_mass": 32803.0, "monoisotopic_mass": 32803.0 }, "refseq": { "ac": "NP_998294", "name": "ankyrin repeat family A protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998294" }, "gene_names": [ { "name": "ankra2", "type": "recommended", "evidence": [ { "id": "A2BGZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3" } ] }, { "name": "ankra2", "type": "synonym", "evidence": [ { "id": "NP_998294", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998294" } ] }, { "name": "wu:fd08c02", "type": "synonym", "evidence": [ { "id": "NP_998294", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998294" }, { "id": "A2BGZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3" } ] }, { "name": "zgc:64138", "type": "synonym", "evidence": [ { "id": "NP_998294", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998294" }, { "id": "A2BGZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3" } ] } ], "protein_names": [ { "name": "Ankyrin repeat family A protein 2", "type": "synonym", "evidence": [ { "id": "A2BGZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat family A protein 2", "type": "synonym", "evidence": [ { "id": "NP_998294", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998294" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC152279.1, GDQH01021174.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On or before Jun 27, 2024 this sequence version replaced XP_005171884.1, NP_998294.1.", "evidence": [ { "database": "RefSeq", "id": "NP_998294", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998294" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BGZ3", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ankra2", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040426-2141", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2141", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000035399", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000035399", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "406403", "url": "https://www.ncbi.nlm.nih.gov/gene/406403", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:406403", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:406403", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A2BGZ3", "url": "https://www.orthodb.org/?gene=A2BGZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24124", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24124", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24124:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24124:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_998294", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998294", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2BGZ3", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BGZ3-1", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040426-2141", "url": "https://zfin.org/ZDB-GENE-040426-2141", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASEEMEGLCPLPEVTGIKVEPSVSIGSTEDASSQNAMGIKFILPNRFDMNVCSRFVKSLNEEDSKNIQDQVNSDLEVASVLFKAECNIQTSPSPGIQVRHVYTPSTTKHFSPIKQSTTLTNKHRGNEVSSTPLLVHSLSIHQLAAQGEMVFLASRIEQESVINLQDEEGFTPLMWAAAHGQIAVVEFLLQSGADPHLLAKGRESALSLACSKGYTDIVRMLIDCGVDVNEYDWNGGAPLLYAVHGNHVRCVEILLESGSDPTMESDSGFNAMDMAVAMGHRNVQQVLEAHLLKLLQGIKE", "length": 301, "header": "tr|A2BGZ3-1|A2BGZ3_DANRE Isoform 1 of Ankyrin repeat family A protein 2 OS=Danio rerio OX=7955 GN=ankra2 PE=4 SV=1 CANONICAL=A2BGZ3-1" }, "isoforms": [ { "isoform_ac": "A2BGZ3-1", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3/entry#A2BGZ3-1", "sequence": { "sequence": "MASEEMEGLCPLPEVTGIKVEPSVSIGSTEDASSQNAMGIKFILPNRFDMNVCSRFVKSLNEEDSKNIQDQVNSDLEVASVLFKAECNIQTSPSPGIQVRHVYTPSTTKHFSPIKQSTTLTNKHRGNEVSSTPLLVHSLSIHQLAAQGEMVFLASRIEQESVINLQDEEGFTPLMWAAAHGQIAVVEFLLQSGADPHLLAKGRESALSLACSKGYTDIVRMLIDCGVDVNEYDWNGGAPLLYAVHGNHVRCVEILLESGSDPTMESDSGFNAMDMAVAMGHRNVQQVLEAHLLKLLQGIKE", "length": 301, "header": "tr|A2BGZ3-1|A2BGZ3_DANRE Isoform 1 of Ankyrin repeat family A protein 2 OS=Danio rerio OX=7955 GN=ankra2 PE=4 SV=1 CANONICAL=A2BGZ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis.", "journal": "Genome Res.", "date": "2003", "authors": "Lo Jane, Lee Sorcheng, Xu Min, Liu Feng, Ruan Hua, Eun Alvin, He Yawen, Ma Weiping, Wang Weefuen, Wen Zilong, Peng Jinrong", "evidence": [ { "database": "UniProtKB", "id": "A2BGZ3", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3" } ], "reference": [ { "type": "PubMed", "id": "12618376", "url": "https://glygen.org/publication/PubMed/12618376" } ] }, { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "A2BGZ3", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] } ], "pathway": [ { "id": "dre:406403", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:406403", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q99PE2-1", "protein_name": "Ankyrin repeat family A protein 2", "gene_name": "Ankra2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATSANLDIGAQLIVEECPSSYISGMPDIKLEHQLDPNPDEGAAQGVAMGMKFILPNRFDMNVCSRFVKSLNEEDSKNIQDQVNSDLEVASVLFKAECNIHTSPSPGIQVRHVYTPSTTKHFSPIKQSTTLTNKHRGNEVSTTPLLANSLSAHQLAAQGEMLYLATRIEQENVINHTDEEGFTPLMWAAAHGQIAVVEFLLQNGADPQLLGKGRESALSLACSKGYTDIVKMLLDCGVDVNEYDWNGGTPLLYAVHGNHVKCVKMLLENGADPTIETDSGYNSMDLAVALGYRGVQQAIESHLLKLLQNIRE", "length": 312 }, "evidence": [ { "id": "MGI:1915808", "url": "https://alliancegenome.org/gene/MGI:1915808#orthology", "database": "AGR" }, { "id": "HGNC:13208", "url": "https://alliancegenome.org/gene/HGNC:13208#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2141", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2141#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H9E1-1", "protein_name": "Ankyrin repeat family A protein 2", "gene_name": "ANKRA2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTSTNLDIGAQLIVEECPSTYSLTGMPDIKIEHPLDPNSEEGSAQGVAMGMKFILPNRFDMNVCSRFVKSLNEEDSKNIQDQVNSDLEVASVLFKAECNIHTSPSPGIQVRHVYTPSTTKHFSPIKQSTTLTNKHRGNEVSTTPLLANSLSVHQLAAQGEMLYLATRIEQENVINHTDEEGFTPLMWAAAHGQIAVVEFLLQNGADPQLLGKGRESALSLACSKGYTDIVKMLLDCGVDVNEYDWNGGTPLLYAVHGNHVKCVKMLLESGADPTIETDSGYNSMDLAVALGYRSVQQVIESHLLKLLQNIKE", "length": 313 }, "evidence": [ { "id": "MGI:1915808", "url": "https://alliancegenome.org/gene/MGI:1915808#orthology", "database": "AGR" }, { "id": "HGNC:13208", "url": "https://alliancegenome.org/gene/HGNC:13208#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2141", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2141#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VL58-1", "protein_name": "DNA-binding protein RFXANK", "gene_name": "Dmel\\CG5846", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVAPANTIQTNANSDDDEGVRSAPTSMLVLDAKRKSAFLPYRPQSTVLTNLQRGNTEATFCPVEVSLSFHERAGQGEITEEQVAAERARQQNIDYKDAHGFTALHWAASYGQLVSVQLLVAAGANVNTMAPDLISPLLLAAAGGHNEIVRFLLEHGADSGHMDIVGNTALMYAAAGNHPHTCNELLAKDLDLSATNEDGDTAYSLAVEHGAHLAQALLEQYMTAIITAGAFGSI", "length": 234 }, "evidence": [ { "id": "MGI:1915808", "url": "https://alliancegenome.org/gene/MGI:1915808#orthology", "database": "AGR" }, { "id": "HGNC:13208", "url": "https://alliancegenome.org/gene/HGNC:13208#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2BGZ3", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A2BGZ3", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of gene expression", "id": "GO:0010468", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010468", "evidence": [ { "database": "UniProtKB", "id": "A2BGZ3", "url": "https://www.uniprot.org/uniprotkb/A2BGZ3" } ], "pmid": "" } ] } ] }, 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2BHB8-1", "uniprot_ac": "A2BHB8", "uniprot_id": "A2BHB8_DANRE", "mass": { "chemical_mass": 17688.0, "monoisotopic_mass": 17688.0 }, "refseq": { "ac": "NP_001191098", "name": "ubiquitin-like protein ISG15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191098" }, "gene_names": [ { "name": "isg15", "type": "recommended", "evidence": [ { "id": "A2BHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ] }, { "name": "g1p2", "type": "synonym", "evidence": [ { "id": "NP_001191098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191098" }, { "id": "A2BHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ] }, { "name": "isg15", "type": "synonym", "evidence": [ { "id": "NP_001191098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191098" } ] }, { "name": "si:rp71-1c23.2", "type": "synonym", "evidence": [ { "id": "NP_001191098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191098" }, { "id": "A2BHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ] } ], "protein_names": [ { "name": "Ubiquitin-like protein ISG15", "type": "synonym", "evidence": [ { "id": "A2BHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHB8/entry#names_and_taxonomy" } ] }, { "name": "interferon stimulated gene, 15 kDa", "type": "synonym", "evidence": [ { "id": "NP_001191098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191098" } ] }, { "name": "interferon, alpha-inducible protein", "type": "synonym", "evidence": [ { "id": "NP_001191098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191098" } ] }, { "name": "ubiquitin-like protein ISG15", "type": "synonym", "evidence": [ { "id": "NP_001191098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191098" } ] }, { "name": "zfISG15", "type": "synonym", "evidence": [ { "id": "NP_001191098", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191098" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH451365.1, EH506698.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH451365.1, EH521603.1 and EH563798.1. On Feb 18, 2011 this sequence version replaced XP_687341.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001191098", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191098" } ] } ], "disease": [ { "disease_id": "DOID:0111934", "recommended_name": { "id": "DOID:0111934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111934", "name": "immunodeficiency 38", "description": "A primary immunodeficiency disease characterized by development of severe clinical disease upon infection with weakly virulent mycobacteria and intracranial calcification that has_material_basis_in homozygous or compound heterozygous mutation in the ISG15 gene on chromosome 1p36.33." }, "synonyms": [ { "id": "DOID:0111934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111934", "name": "Mendelian susceptibility to mycobacterial diseases due to complete ISG15 deficiency", "description": "" }, { "id": "DOID:0111934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111934", "name": "IMD38", "description": "" }, { "id": "DOID:0111934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111934", "name": "immunodeficiency 38 with basal ganglia calcification", "description": "" }, { "id": "DOID:0111934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111934", "name": "autosomal recessive ISG15 deficiency", "description": "" }, { "id": "DOID:0111934", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111934", "name": "immunodeficiency 38, mycobacteriosis, autosomal recessive", "description": "" }, { "id": "MONDO:0014502", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014502", "name": "Mendelian susceptibility to mycobacterial diseases due to complete ISG15 deficiency", "description": "Mendelian susceptibility to mycobacterial diseases (MSMD) due to complete ISG15 deficiency is a genetic variant of MSMD characterized by Bacille Calmette-GuC)rin (BCG) infections." }, { "id": "MONDO:0014502", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014502", "name": "ISG15 autosomal recessive mendelian susceptibility to mycobacterial diseases due to a complete deficiency", "description": "" }, { "id": "MONDO:0014502", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014502", "name": "MSMD due to complete ISG15 deficiency", "description": "" }, { "id": "MONDO:0014502", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014502", "name": "autosomal recessive mendelian susceptibility to mycobacterial diseases due to a complete deficiency caused by mutation in ISG15", "description": "" }, { "id": "MONDO:0014502", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014502", "name": "IMD38", "description": "" }, { "id": "MONDO:0014502", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014502", "name": "immunodeficiency 38 with basal ganglia calcification", "description": "" }, { "id": "MIM:616126", "resource": "MIM", "url": "https://www.omim.org/entry/616126", "name": "Immunodeficiency 38, with basal ganglia calcification", "description": "Immunodeficiency 38, with basal ganglia calcification" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111934", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111934" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "isg15", "url": "https://www.uniprot.org/uniprotkb/A2BHB8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-021211-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021211-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000086374", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000086374", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01810", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01810", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "558956", "url": "https://www.ncbi.nlm.nih.gov/gene/558956", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558956", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558956", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTVYMNL", "url": "https://omabrowser.org/oma/group/CTVYMNL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2BHB8", "url": "https://www.orthodb.org/?gene=A2BHB8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001191098", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001191098", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BHB8-1", "url": "https://www.uniprot.org/uniprotkb/A2BHB8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-021211-1", "url": "https://zfin.org/ZDB-GENE-021211-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MQLTVKLLGGDVKRLEVSGDATVGILKQVISQYFNVPTFKQKLSAENGQRISLEDESRTLSSYGLNSDSVVMLLITTNPGTFQVFVKNEKGQVKTYDVDANETVDQLQTKIYQKERVPKDQQRLIFKGRQLESGMKLQDYDITSLSTIHMTLRLRGG", "length": 157, "header": "tr|A2BHB8-1|A2BHB8_DANRE Isoform 1 of Ubiquitin-like protein ISG15 OS=Danio rerio OX=7955 GN=isg15 PE=1 SV=1 CANONICAL=A2BHB8-1" }, "isoforms": [ { "isoform_ac": "A2BHB8-1", "url": "https://www.uniprot.org/uniprotkb/A2BHB8/entry#A2BHB8-1", "sequence": { "sequence": "MQLTVKLLGGDVKRLEVSGDATVGILKQVISQYFNVPTFKQKLSAENGQRISLEDESRTLSSYGLNSDSVVMLLITTNPGTFQVFVKNEKGQVKTYDVDANETVDQLQTKIYQKERVPKDQQRLIFKGRQLESGMKLQDYDITSLSTIHMTLRLRGG", "length": 157, "header": "tr|A2BHB8-1|A2BHB8_DANRE Isoform 1 of Ubiquitin-like protein ISG15 OS=Danio rerio OX=7955 GN=isg15 PE=1 SV=1 CANONICAL=A2BHB8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Molecular cloning of the fish interferon stimulated gene, 15 kDa (ISG15) orthologue: a ubiquitin-like gene induced by nephrotoxic damage.", "journal": "Gene", "date": "2002", "authors": "Liu M, Reimschuessel R, Hassel BA", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "reference": [ { "type": "PubMed", "id": "12426101", "url": "https://glygen.org/publication/PubMed/12426101" } ] }, { "title": "Hematopoietic gene expression profile in zebrafish kidney marrow.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2004", "authors": "Song Huai-Dong, Sun Xiao-Jian, Deng Min, Zhang Guo-Wei, Zhou Yi, Wu Xin-Yan, Sheng Yan, Chen Yi, Ruan Zheng, Jiang Chun-Lei, Fan Hui-Yong, Zon Leonard I, Kanki John P, Liu Ting Xi, Look A Thomas, Chen Zhu", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "reference": [ { "type": "PubMed", "id": "15520368", "url": "https://glygen.org/publication/PubMed/15520368" } ] }, { "title": "Sequence and expression analysis of an interferon stimulated gene (ISG15) from Atlantic cod (Gadus morhua L.).", "journal": "Dev. Comp. Immunol.", "date": "2007", "authors": "Seppola Marit, Stenvik J\u00f8rgen, Steiro Kari, Solstad Terese, Robertsen B\u00f8rre, Jensen Ingvill", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "reference": [ { "type": "PubMed", "id": "16824598", "url": "https://glygen.org/publication/PubMed/16824598" } ] }, { "title": "Activation of cytokine expression occurs through the TNFalpha/NF-kappaB-mediated pathway in birnavirus-infected cells.", "journal": "Fish Shellfish Immunol.", "date": "2011", "authors": "Wang Wei-Lun, Liu Wangta, Gong Hong-Yi, Hong Jiann-Ruey, Lin Ching-Chun, Wu Jen-Leih", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "reference": [ { "type": "PubMed", "id": "21272652", "url": "https://glygen.org/publication/PubMed/21272652" } ] }, { "title": "Characterization of a PIAS4 Homologue from Zebrafish: Insights into Its Conserved Negative Regulatory Mechanism in the TRIF, MAVS, and IFN Signaling Pathways during Vertebrate Evolution.", "journal": "J. Immunol.", "date": "2012", "authors": "Xiong Ran, Nie Li, Xiang Li-xin, Shao Jian-zhong", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "reference": [ { "type": "PubMed", "id": "22345667", "url": "https://glygen.org/publication/PubMed/22345667" } ] }, { "title": "Distinct features of the regenerating heart uncovered through comparative single-cell profiling.", "journal": "Biol. Open", "date": "2024", "authors": "Carey Clayton M, Hollins Hailey L, Schmid Alexis V, Gagnon James A", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "reference": [ { "type": "PubMed", "id": "38526188", "url": "https://glygen.org/publication/PubMed/38526188" } ] }, { "title": "Macrophage transplantation rescues RNASET2-deficient leukodystrophy by replacing deficient microglia in a zebrafish model.", "journal": "Proc. Natl. Acad. Sci.", "date": "2024", "authors": "Renshaw S.A., Hamilton N., Duncan C.J.A., Rutherford H.A., Candeias D.", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "reference": [ { "type": "PubMed", "id": "38753517", "url": "https://glygen.org/publication/PubMed/38753517" } ] }, { "title": "Second generation lethality in RNAseH2a knockout zebrafish.", "journal": "Nucleic Acids Res.", "date": "2024", "authors": "Thomas Ruth C, Zaksauskaite Ringaile, Al-Kandari Norah Y, Hyde Anne Cathrine, Abugable Arwa A, El-Khamisy Sherif F, van Eeden Freek J", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "reference": [ { "type": "PubMed", "id": "39217460", "url": "https://glygen.org/publication/PubMed/39217460" } ] }, { "title": "Transcripts of repetitive DNA elements signal to block phagocytosis of hematopoietic stem cells.", "journal": "Science", "date": "2024", "authors": "Pessoa Rodrigues Cecilia, Collins Joseph M, Yang Song, Martinez Catherine, Kim Ji Wook, Lama Chhiring, Nam Anna S, Alt Clemens, Lin Charles, Zon Leonard I", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "reference": [ { "type": "PubMed", "id": "39264994", "url": "https://glygen.org/publication/PubMed/39264994" } ] }, { "title": "Emc1 is essential for vision and zebrafish photoreceptor outer segment morphogenesis.", "journal": "FASEB J.", "date": "2024", "authors": "Swaroop A., Taylor M.R., Geisler R., Walsh C., Moran A., McCann T., Kennedy B.N., Alvarez Y., Collery R.F., English M.A., Sapetto-Rebow B., Sundaramurthi H., O'Connor J.J., Reynolds A.L., Carter S.P., Mulholland R., Rauch N., Starostik M.R., Virdi S.", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "reference": [ { "type": "PubMed", "id": "39360639", "url": "https://glygen.org/publication/PubMed/39360639" } ] } ], "pathway": [ { "id": "dre:558956", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558956", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AB58-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGRELKVKMLGGKEILVPLRDCMMASDLKQQIAREIGVPAFQQRLAHPAGNVLQDGVPLVNQGLGPGSTVLLMVQSFRDPLSILVRNDKGRSNAYEVWLTQTVAELKQQVCQQEGVQADQFWLTFEGKPMEDEHQLGEYDLKPMCTVYMNLRLRGGGTGPGEHLTEC", "length": 167 }, "evidence": [ { "id": "A2BHB8", "url": "https://omabrowser.org/oma/group/A2BHB8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D4A3X3-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "Isg15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTWNLKVKMLGGKEFLVSMTNSMMLSELKKQVAQKSGVPAFQQRLAHQSGEMLQDGVALIRQGLSSGSTVMLMVENCSHPLSILVRNERGRSNVYEVQLTQTVEVLMRQVSQHEQVSQDQFWLSFNGRPMEDKEPLGEYGLTPHCTVIMNLRLRGGGDYYF", "length": 161 }, "evidence": [ { "id": "MGI:1855694", "url": "https://alliancegenome.org/gene/MGI:1855694#orthology", "database": "AGR" }, { "id": "HGNC:4053", "url": "https://alliancegenome.org/gene/HGNC:4053#orthology", "database": "AGR" }, { "id": "A2BHB8", "url": "https://omabrowser.org/oma/group/A2BHB8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O02741-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGGDLTVKMLGGQEILVPLRDSMTVSELKQFIAQKINVPAFQQRLAHLDSREVLQEGVPLVLQGLRAGSTVLLVVQNCISILVRNDKGRSSPYEVQLKQTVAELKQQVCQKERVQADQFWLSFEGRPMDDEHPLEEYGLMKGCTVFMNLRLRGG", "length": 154 }, "evidence": [ { "id": "A2BHB8", "url": "https://omabrowser.org/oma/group/A2BHB8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P05161-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "ISG15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGWDLTVKMLAGNEFQVSLSSSMSVSELKAQITQKIGVHAFQQRLAVHPSGVALQDRVPLASQGLGPGSTVLLVVDKCDEPLSILVRNNKGRSSTYEVRLTQTVAHLKQQVSGLEGVQDDLFWLTFEGKPLEDQLPLGEYGLKPLSTVFMNLRLRGGGTEPGGRS", "length": 165 }, "evidence": [ { "id": "MGI:1855694", "url": "https://alliancegenome.org/gene/MGI:1855694#orthology", "database": "AGR" }, { "id": "HGNC:4053", "url": "https://alliancegenome.org/gene/HGNC:4053#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-021211-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021211-1#orthology", "database": "AGR" }, { "id": "A2BHB8", "url": "https://omabrowser.org/oma/group/A2BHB8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64339-1", "protein_name": "Ubiquitin-like protein ISG15", "gene_name": "Isg15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWDLKVKMLGGNDFLVSVTNSMTVSELKKQIAQKIGVPAFQQRLAHQTAVLQDGLTLSSLGLGPSSTVMLVVQNCSEPLSILVRNERGHSNIYEVFLTQTVDTLKKKVSQREQVHEDQFWLSFEGRPMEDKELLGEYGLKPQCTVIKHLRLRGGGGDQCA", "length": 161 }, "evidence": [ { "id": "MGI:1855694", "url": "https://alliancegenome.org/gene/MGI:1855694#orthology", "database": "AGR" }, { "id": "HGNC:4053", "url": "https://alliancegenome.org/gene/HGNC:4053#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-021211-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-021211-1#orthology", "database": "AGR" }, { "id": "A2BHB8", "url": "https://omabrowser.org/oma/group/A2BHB8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "pmid": "" }, { "name": "cytosolic ribosome", "id": "GO:0022626", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0022626", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "pmid": "" }, { "name": "modification-dependent protein catabolic process", "id": "GO:0019941", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019941", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "structural constituent of ribosome", "id": "GO:0003735", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003735", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "pmid": "" }, { "name": "protein tag activity", "id": "GO:0031386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031386", "evidence": [ { "database": "UniProtKB", "id": "A2BHB8", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A2BHB8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHB8" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 80, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2BHI0-1", "uniprot_ac": "A2BHI0", "uniprot_id": "A2BHI0_DANRE", "mass": { "chemical_mass": 62422.0, "monoisotopic_mass": 62422.0 }, "refseq": { "ac": "XP_695158", "name": "protein FAM83F", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695158" }, "gene_names": [ { "name": "fam83fa", "type": "recommended", "evidence": [ { "id": "A2BHI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHI0" } ] }, { "name": "fam83fa", "type": "synonym", "evidence": [ { "id": "XP_695158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695158" } ] } ], "protein_names": [ { "name": "Protein FAM83F", "type": "synonym", "evidence": [ { "id": "A2BHI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHI0/entry#names_and_taxonomy" } ] }, { "name": "protein FAM83F", "type": "synonym", "evidence": [ { "id": "XP_695158", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695158" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_695158.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_695158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695158" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BHI0", "url": "https://www.uniprot.org/uniprotkb/A2BHI0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam83fa", "url": "https://www.uniprot.org/uniprotkb/A2BHI0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090624-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090624-5", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000038012", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000038012", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "566780", "url": "https://www.ncbi.nlm.nih.gov/gene/566780", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566780", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566780", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTLDIGW", "url": "https://omabrowser.org/oma/group/PTLDIGW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2BHI0", "url": "https://www.orthodb.org/?gene=A2BHI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_695158", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695158", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2BHI0", "url": "https://www.uniprot.org/uniprotkb/A2BHI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BHI0-1", "url": "https://www.uniprot.org/uniprotkb/A2BHI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090624-5", "url": "https://zfin.org/ZDB-GENE-090624-5", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAESQLICMDDEHVNVKIPESKPEFYYSEEQRAALEQLLRNGDGAFKMRLKEDSVKDFLSAREIKWMRETFQEYDSDSDTCCSRSPHDTSEDSGVHSTYWPTMSDTEIPPLDIGWPSNGHYKGVTRVSVYTHPPKSNSPHIKEVVRKLIQESTKLIAVVMDLVTDLLILQDLLDAASKRGVAVYLLLEENGLPHFLDMSSRLQISAQHLRNLRVQTVRGSGMPLSFGRLPGSLCSKYMLVDGEKVMFGSYSFTWSSSRMNRNTITVMSGQVVDFFDNDFRELYAVSDKVDLYREFHISKPAMQVPVLKTPSEPIKLTVPVSMSRFQISVGDTKPVDLKVPAHKYHNPKYSLVVGNSLGVTGSLQDLSKLRDYVDHASVSNMEKLIYTNGESLHPQSPASPDGTEDTKGEGKKPSPFGSKKQRSSFRNYLKGRANNQSPGALTKTTHQNIDAKQNSPKDIKPTSHSKEASWLDNHVKEKEEPSRHLSPAPRKISDADSTNEVEDTFEFIENPPQVKFKLKKNKLGPRSVSLQTIATDGEDGPRGRRRTQKKNCIQS", "length": 555, "header": "tr|A2BHI0-1|A2BHI0_DANRE Isoform 1 of Protein FAM83F OS=Danio rerio OX=7955 GN=fam83fa PE=3 SV=1 CANONICAL=A2BHI0-1" }, "isoforms": [ { "isoform_ac": "A2BHI0-1", "url": "https://www.uniprot.org/uniprotkb/A2BHI0/entry#A2BHI0-1", "sequence": { "sequence": "MAESQLICMDDEHVNVKIPESKPEFYYSEEQRAALEQLLRNGDGAFKMRLKEDSVKDFLSAREIKWMRETFQEYDSDSDTCCSRSPHDTSEDSGVHSTYWPTMSDTEIPPLDIGWPSNGHYKGVTRVSVYTHPPKSNSPHIKEVVRKLIQESTKLIAVVMDLVTDLLILQDLLDAASKRGVAVYLLLEENGLPHFLDMSSRLQISAQHLRNLRVQTVRGSGMPLSFGRLPGSLCSKYMLVDGEKVMFGSYSFTWSSSRMNRNTITVMSGQVVDFFDNDFRELYAVSDKVDLYREFHISKPAMQVPVLKTPSEPIKLTVPVSMSRFQISVGDTKPVDLKVPAHKYHNPKYSLVVGNSLGVTGSLQDLSKLRDYVDHASVSNMEKLIYTNGESLHPQSPASPDGTEDTKGEGKKPSPFGSKKQRSSFRNYLKGRANNQSPGALTKTTHQNIDAKQNSPKDIKPTSHSKEASWLDNHVKEKEEPSRHLSPAPRKISDADSTNEVEDTFEFIENPPQVKFKLKKNKLGPRSVSLQTIATDGEDGPRGRRRTQKKNCIQS", "length": 555, "header": "tr|A2BHI0-1|A2BHI0_DANRE Isoform 1 of Protein FAM83F OS=Danio rerio OX=7955 GN=fam83fa PE=3 SV=1 CANONICAL=A2BHI0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:566780", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566780", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4IIC5-1", "protein_name": "Uncharacterized protein LOC492354", "gene_name": "fam83fb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESQLEALEDGQIPPAVPESRPQFYYSERQRVALEQLITGGDGAFKTYLKEEQSHDFLSAREIKNITGSFVKYQEEDGGGAGAERGPGGAKTDSMHSTYWPQMSDTEVPPLDMGWPSSGLFKGVTRVSVHTHPPKPNSPHIKEVARKLIQEASKVIAIVMDLLTDLQILQDIFEASQRGVPVYMVLDLLGAPHFLDMCSRMQVGAKQLQNVRTRTVRGVGLNLSMGRIPGNVHSKYMLIDGDKVMFGTYSFCWSSSRMDRNMITVMSGQIVDFYDHDFRELYANSDKLDLFKEFHLSKPQTGTLSRAAVSKRPPAATSRFQVNLGDATRGDLKIPAHKYHNPKYLLALGQIPGPAEPMQEFLKTMEPQNPEDLLEDLQGEPENLPVETEKKKKNKRQKKKEKKKKKGDNTSDVVIDDNTSKHADENFEKTSMKKRSCFWRCFVKSK", "length": 447 }, "evidence": [ { "id": "HGNC:25148", "url": "https://alliancegenome.org/gene/HGNC:25148#orthology", "database": "AGR" }, { "id": "MGI:2146227", "url": "https://alliancegenome.org/gene/MGI:2146227#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZAT7-1", "protein_name": "Family with sequence similarity 83, member F", "gene_name": "Fam83f", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAESQLNCLDEAHVNERVTEAHAAFYYCERRRAALEALLGGSEQAYRERVKKERLRDFLSSQERQALCAAWSPYEEAVSNTRAKAKAKAKSHSRAEPGESLAYWPDRSDTEVPPLDLGWTDSSFYRGVSRVTLFTHPPKEEKAPHLKQVVRQMIQQAQKVIAVVMDLFTDGDIFQDIVDAASKRRVPVYIILDEGGVKFFLEMCQGLELADFRIRNIRVRSVTGVGFYMPMGKIKGTLSSKFLMVDGDKVATGSYSFTWSSSYVDRNLLLLLTGQNVEPFDIEFRELYAISEEVNLHQHLGLAGRIGLNYSSTVARKLINPKYALVAGTRPPPGEMMRWAARQQRDAGGNPEGQEEGSGGGESARRLESFLNDLVTVEQVLPTVDPIIPRLPKPNDGKTTSYAHTDLRHKSREALPQNGKGEAANGEATPAKESRRFSSRFFSRRVKRPTVHSSMAGSPSTETFTDVEFQLGKRHNEGSMANISGRGSSSVTKASNCVIS", "length": 500 }, "evidence": [ { "id": "HGNC:25148", "url": "https://alliancegenome.org/gene/HGNC:25148#orthology", "database": "AGR" }, { "id": "MGI:2146227", "url": "https://alliancegenome.org/gene/MGI:2146227#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UKU4-1", "protein_name": "Protein FAM83F", "gene_name": "Fam83f", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAESQLSCLDEAHVNERVTEAHAAFYYCERRRAALEALLGGGEQAYRELVKKERLRDFLSSQERQALCAAWSPYEEAVSSTRAKAKAKAKFPAQPTESLAYWPDRSDTEVPPLDLGWTDTNFYRGVSRVTLFTHPPKEEKAPHLKQVVRQMIQQAQKVIAVVMDLFTDGDIFQDIVDAACKRRVPVYIILDEGGVKYFLEMCQGLELADFRIRNIRVRSVTGIGFYMPMGKIKGTLSSKFLMVDGDKVATGSFSFTWSSSYVDRNLLLLLTGQNMEPFDIEFRELYAISEEVNLHQHLGLAGRIGLNYSSTVARKLINPKYALVAGTRRPPGEMMRWAARQQREAGGNVEGQEEGSGGGESARRLESFLNDLVTVEQILPTVEPISPRLQRPTNGRPVSHAHTDAKHRSREALPQNGKGEAANGEATPAKEGKRFSSRLFSRRVKRPAVPSSMASSPSTETFADVEFPLGKRHNEGSNANISGKGITKASNCVIS", "length": 495 }, "evidence": [ { "id": "HGNC:25148", "url": "https://alliancegenome.org/gene/HGNC:25148#orthology", "database": "AGR" }, { "id": "MGI:2146227", "url": "https://alliancegenome.org/gene/MGI:2146227#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090624-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090624-5#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NEG4-1", "protein_name": "Protein FAM83F", "gene_name": "FAM83F", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESQLNCLDEAHVNEKVTEAQAAFYYCERRRAALEALLGGGEQAYRERLKEEQLRDFLSSPERQALRAAWSPYEDAVPAANARGKSKAKAKAPAPAPAESGESLAYWPDRSDTEVPPLDLGWTDTGFYRGVSRVTLFTHPPKDEKAPHLKQVVRQMIQQAQKVIAVVMDLFTDGDIFQDIVDAACKRRVPVYIILDEAGVKYFLEMCQDLQLTDFRIRNIRVRSVTGVGFYMPMGRIKGTLSSRFLMVDGDKVATGSYRFTWSSSHVDRNLLLLLTGQNVEPFDTEFRELYAISEEVDLYRQLSLAGRVGLHYSSTVARKLINPKYALVSGCRHPPGEMMRWAARQQREAGGNPEGQEEGASGGESAWRLESFLKDLVTVEQVLPPVEPIPLGELSQKDGRMVSHMHRDLKPKSREAPSRNGMGEAARGEAAPARRFSSRLFSRRAKRPAAPNGMASSVSTETSEVEFLTGKRPNENSSADISGKTSPSSAKPSNCVIS", "length": 500 }, "evidence": [ { "id": "HGNC:25148", "url": "https://alliancegenome.org/gene/HGNC:25148#orthology", "database": "AGR" }, { "id": "MGI:2146227", "url": "https://alliancegenome.org/gene/MGI:2146227#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090624-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090624-5#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "A2BHI0", "url": "https://www.uniprot.org/uniprotkb/A2BHI0" } ], "pmid": "" }, { "name": "hatching", "id": "GO:0035188", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035188", "evidence": [ { "database": "UniProtKB", "id": "A2BHI0", "url": "https://www.uniprot.org/uniprotkb/A2BHI0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "A2BHI0", "url": "https://www.uniprot.org/uniprotkb/A2BHI0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 435, "end_pos": 437, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A2BHI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHI0" }, { "id": "PF07894", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Scaffolding anchor of CK1", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 287, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 435, "end_pos": 437 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A2BHK1-1", "uniprot_ac": "A2BHK1", "uniprot_id": "A2BHK1_DANRE", "mass": { "chemical_mass": 23734.0, "monoisotopic_mass": 23734.0 }, "refseq": { "ac": "NP_001107128", "name": "uncharacterized protein LOC100004976", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107128" }, "gene_names": [ { "name": "si:dkey-58f10.10", "type": "recommended", "evidence": [ { "id": "A2BHK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHK1" } ] }, { "name": "si:dkey-58f10.10", "type": "synonym", "evidence": [ { "id": "NP_001107128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107128" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100004976", "type": "synonym", "evidence": [ { "id": "A2BHK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHK1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100004976", "type": "synonym", "evidence": [ { "id": "NP_001107128", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107128" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: DT078302.1, DT062490.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476746, SAMEA708836 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000005.1. On Jan 20, 2008 this sequence version replaced XP_001339536.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001107128", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107128" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BHK1", "url": "https://www.uniprot.org/uniprotkb/A2BHK1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-58f10.10", "url": "https://www.uniprot.org/uniprotkb/A2BHK1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-312", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-312", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000094284", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000094284", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100004976", "url": "https://www.ncbi.nlm.nih.gov/gene/100004976", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100004976", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004976", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A2BHK1", "url": "https://www.orthodb.org/?gene=A2BHK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34488", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34488", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34488:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34488:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001107128", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107128", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2BHK1", "url": "https://www.uniprot.org/uniprotkb/A2BHK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BHK1-1", "url": "https://www.uniprot.org/uniprotkb/A2BHK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-312", "url": "https://zfin.org/ZDB-GENE-060526-312", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDKFIGDFQRRLHKEVYGLREVTILEHCGFIMYFCLITSRAGTDIDAAIRNLMLVQADKQVIIAVLYPTIDPEKTIPDSNNAIKKENTYLVDFLFNEDEGFMNCQKNKDAINKLARHIKSMNLTSYYLQNYGIPRTYQNGEDSLVPIGAGGHRIRKKCVIFLFLIVIIILIICFIIFWTVLRHHVDTNDINNYRNDTVKKYNSF", "length": 204, "header": "tr|A2BHK1-1|A2BHK1_DANRE Isoform 1 of Uncharacterized protein LOC100004976 OS=Danio rerio OX=7955 GN=si:dkey-58f10.10 PE=4 SV=1 CANONICAL=A2BHK1-1" }, "isoforms": [ { "isoform_ac": "A2BHK1-1", "url": "https://www.uniprot.org/uniprotkb/A2BHK1/entry#A2BHK1-1", "sequence": { "sequence": "MDKFIGDFQRRLHKEVYGLREVTILEHCGFIMYFCLITSRAGTDIDAAIRNLMLVQADKQVIIAVLYPTIDPEKTIPDSNNAIKKENTYLVDFLFNEDEGFMNCQKNKDAINKLARHIKSMNLTSYYLQNYGIPRTYQNGEDSLVPIGAGGHRIRKKCVIFLFLIVIIILIICFIIFWTVLRHHVDTNDINNYRNDTVKKYNSF", "length": 204, "header": "tr|A2BHK1-1|A2BHK1_DANRE Isoform 1 of Uncharacterized protein LOC100004976 OS=Danio rerio OX=7955 GN=si:dkey-58f10.10 PE=4 SV=1 CANONICAL=A2BHK1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A2BHK1", "url": "https://www.uniprot.org/uniprotkb/A2BHK1" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:100004976", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004976", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 195, "end_pos": 197 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2BHK9-1", "uniprot_ac": "A2BHK9", "uniprot_id": "A2BHK9_DANRE", "mass": { "chemical_mass": 13861.0, "monoisotopic_mass": 13861.0 }, "refseq": { "ac": "NP_001094429", "name": "uncharacterized protein LOC793802", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094429" }, "gene_names": [ { "name": "si:dkey-111e8.4", "type": "recommended", "evidence": [ { "id": "A2BHK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHK9" } ] }, { "name": "si:dkey-111e8.4", "type": "synonym", "evidence": [ { "id": "NP_001094429", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094429" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC793802", "type": "synonym", "evidence": [ { "id": "A2BHK9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHK9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC793802", "type": "synonym", "evidence": [ { "id": "NP_001094429", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094429" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CO355467.1, SRR32588722.16025600.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715720 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000005.1. On Aug 12, 2007 this sequence version replaced XP_001332446.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001094429", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094429" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BHK9", "url": "https://www.uniprot.org/uniprotkb/A2BHK9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-111e8.4", "url": "https://www.uniprot.org/uniprotkb/A2BHK9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-191", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-191", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000093547", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000093547", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "793802", "url": "https://www.ncbi.nlm.nih.gov/gene/793802", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:793802", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793802", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TDHYSGM", "url": "https://omabrowser.org/oma/group/TDHYSGM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2BHK9", "url": "https://www.orthodb.org/?gene=A2BHK9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001094429", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001094429", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2BHK9", "url": "https://www.uniprot.org/uniprotkb/A2BHK9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BHK9-1", "url": "https://www.uniprot.org/uniprotkb/A2BHK9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-191", "url": "https://zfin.org/ZDB-GENE-060526-191", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEAGGSLSQWLNSDIFIVFVVLLLLLLLVIFAVCWLMRRQYTQRPPEKMAEIEIIPVNSADAGNPSRFTLKIVTEQTHATELVEMLTQRGRCVEPLNTHRNPSVSADAADSDSDQDFTDALQSI", "length": 124, "header": "tr|A2BHK9-1|A2BHK9_DANRE Isoform 1 of Uncharacterized protein LOC793802 OS=Danio rerio OX=7955 GN=si:dkey-111e8.4 PE=4 SV=1 CANONICAL=A2BHK9-1" }, "isoforms": [ { "isoform_ac": "A2BHK9-1", "url": "https://www.uniprot.org/uniprotkb/A2BHK9/entry#A2BHK9-1", "sequence": { "sequence": "MEAGGSLSQWLNSDIFIVFVVLLLLLLLVIFAVCWLMRRQYTQRPPEKMAEIEIIPVNSADAGNPSRFTLKIVTEQTHATELVEMLTQRGRCVEPLNTHRNPSVSADAADSDSDQDFTDALQSI", "length": 124, "header": "tr|A2BHK9-1|A2BHK9_DANRE Isoform 1 of Uncharacterized protein LOC793802 OS=Danio rerio OX=7955 GN=si:dkey-111e8.4 PE=4 SV=1 CANONICAL=A2BHK9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:793802", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793802", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A2BHM3-1", "uniprot_ac": "A2BHM3", "uniprot_id": "A2BHM3_DANRE", "mass": { "chemical_mass": 21992.0, "monoisotopic_mass": 21992.0 }, "refseq": { "ac": "NP_001315076", "name": "uncharacterized protein LOC564884", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315076" }, "gene_names": [ { "name": "si:ch211-271e10.3", "type": "recommended", "evidence": [ { "id": "A2BHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHM3" } ] }, { "name": "si:ch211-271e10.3", "type": "synonym", "evidence": [ { "id": "NP_001315076", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315076" } ] }, { "name": "wu:fb64b08", "type": "synonym", "evidence": [ { "id": "NP_001315076", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315076" }, { "id": "A2BHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHM3" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC564884", "type": "synonym", "evidence": [ { "id": "A2BHM3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BHM3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC564884", "type": "synonym", "evidence": [ { "id": "NP_001315076", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315076" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CK868146.1, DN836123.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN08196788 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1 and CF997561.1. On Jun 7, 2016 this sequence version replaced XP_706325.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001315076", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315076" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BHM3", "url": "https://www.uniprot.org/uniprotkb/A2BHM3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-271e10.3", "url": "https://www.uniprot.org/uniprotkb/A2BHM3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-147", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-147", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092222", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092222", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "564884", "url": "https://www.ncbi.nlm.nih.gov/gene/564884", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:564884", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564884", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YISAVDC", "url": "https://omabrowser.org/oma/group/YISAVDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2BHM3", "url": "https://www.orthodb.org/?gene=A2BHM3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34488", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34488", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34488:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34488:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001315076", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315076", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2BHM3", "url": "https://www.uniprot.org/uniprotkb/A2BHM3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BHM3-1", "url": "https://www.uniprot.org/uniprotkb/A2BHM3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-147", "url": "https://zfin.org/ZDB-GENE-060526-147", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDKFIGDFQRRLHKEVYGLKEVTILEHCGFILYFCLITSRAGTDIDAAIRTLMLVQADKQVIIAVLYPTIDPEKTIPDSNNAIKRENTYLVDFLFNEDEGFMNCQKNIDAIKKLAWYIKSKNLTSYYLQNYGIPRTYTYQNGEDFLFPTRGHSGHRFGGDFWQKNRVACTVIVGVVIFGILLWIILDVLF", "length": 190, "header": "tr|A2BHM3-1|A2BHM3_DANRE Isoform 1 of Uncharacterized protein LOC564884 OS=Danio rerio OX=7955 GN=si:ch211-271e10.3 PE=4 SV=1 CANONICAL=A2BHM3-1" }, "isoforms": [ { "isoform_ac": "A2BHM3-1", "url": "https://www.uniprot.org/uniprotkb/A2BHM3/entry#A2BHM3-1", "sequence": { "sequence": "MDKFIGDFQRRLHKEVYGLKEVTILEHCGFILYFCLITSRAGTDIDAAIRTLMLVQADKQVIIAVLYPTIDPEKTIPDSNNAIKRENTYLVDFLFNEDEGFMNCQKNIDAIKKLAWYIKSKNLTSYYLQNYGIPRTYTYQNGEDFLFPTRGHSGHRFGGDFWQKNRVACTVIVGVVIFGILLWIILDVLF", "length": 190, "header": "tr|A2BHM3-1|A2BHM3_DANRE Isoform 1 of Uncharacterized protein LOC564884 OS=Danio rerio OX=7955 GN=si:ch211-271e10.3 PE=4 SV=1 CANONICAL=A2BHM3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:564884", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564884", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A2BIC9-1", "uniprot_ac": "A2BIC9", "uniprot_id": "A2BIC9_DANRE", "mass": { "chemical_mass": 35662.0, "monoisotopic_mass": 35662.0 }, "refseq": { "ac": "NP_001428882", "name": "uncharacterized protein LOC450058 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428882" }, "gene_names": [ { "name": "f8a", "type": "recommended", "evidence": [ { "id": "A2BIC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIC9" } ] }, { "name": "f8a", "type": "synonym", "evidence": [ { "id": "NP_001428882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428882" } ] }, { "name": "si:ch211-243a20.2", "type": "synonym", "evidence": [ { "id": "NP_001428882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428882" }, { "id": "A2BIC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIC9" } ] }, { "name": "zgc:101679", "type": "synonym", "evidence": [ { "id": "NP_001428882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428882" }, { "id": "A2BIC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIC9" } ] } ], "protein_names": [ { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A2BIC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIC9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC450058 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001428882", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428882" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01010021.1, GDQH01011809.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Jul 14, 2025 this sequence version replaced XP_005160094.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001428882", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428882" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BIC9", "url": "https://www.uniprot.org/uniprotkb/A2BIC9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "f8a", "url": "https://www.uniprot.org/uniprotkb/A2BIC9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041010-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-181", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000025518", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000025518", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "450058", "url": "https://www.ncbi.nlm.nih.gov/gene/450058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000744", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000744", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ELWQYAG", "url": "https://omabrowser.org/oma/group/ELWQYAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2BIC9", "url": "https://www.orthodb.org/?gene=A2BIC9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16797", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16797", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16797:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16797:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14938", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14938", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001428882", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001428882", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2BIC9", "url": "https://www.uniprot.org/uniprotkb/A2BIC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BIC9-1", "url": "https://www.uniprot.org/uniprotkb/A2BIC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A634", "url": "https://www.uniprot.org/uniprotkb/B8A634", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A634-1", "url": "https://www.uniprot.org/uniprotkb/B8A634-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041010-181", "url": "https://zfin.org/ZDB-GENE-041010-181", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAAEGDFLMRYRAVSNKLKKRFLRKPNVAEASEQFGQLAKELKQQDCPQYAAFCNLAMARCEQTLFNAPGEALALTDAARLFLASEQETRALRAPGFDENMQAAMNCYSFAIKVYIEMNQPVMAASLSLELGNALKEMNRPGEAIIHFQRAAELQIQMPIEALLSLWEMASCKILTRDYDGALAVLSEMQHMCQERGLQLPGTNTPVGAFMDIIAKCEISRVLLLMLLEPPPQKLLPEHAQTLERYAWESFDSHSQVNFLPENVFLLLQSVVMACQEKDTESLKALQTELWPLLSAEQNHLLHLVVQERITPFGQGI", "length": 317, "header": "tr|A2BIC9-1|A2BIC9_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=f8a PE=1 SV=2 CANONICAL=A2BIC9-1" }, "isoforms": [ { "isoform_ac": "A2BIC9-1", "url": "https://www.uniprot.org/uniprotkb/A2BIC9/entry#A2BIC9-1", "sequence": { "sequence": "MAAEGDFLMRYRAVSNKLKKRFLRKPNVAEASEQFGQLAKELKQQDCPQYAAFCNLAMARCEQTLFNAPGEALALTDAARLFLASEQETRALRAPGFDENMQAAMNCYSFAIKVYIEMNQPVMAASLSLELGNALKEMNRPGEAIIHFQRAAELQIQMPIEALLSLWEMASCKILTRDYDGALAVLSEMQHMCQERGLQLPGTNTPVGAFMDIIAKCEISRVLLLMLLEPPPQKLLPEHAQTLERYAWESFDSHSQVNFLPENVFLLLQSVVMACQEKDTESLKALQTELWPLLSAEQNHLLHLVVQERITPFGQGI", "length": 317, "header": "tr|A2BIC9-1|A2BIC9_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=f8a PE=1 SV=2 CANONICAL=A2BIC9-1" }, "locus": {} }, { "isoform_ac": "B8A634-1", "url": "https://www.uniprot.org/uniprotkb/A2BIC9/entry#B8A634-1", "sequence": { "sequence": "MAAEGDFLMRYRAVSNKLKKRFLRKPNVAEASEQFGQLAKELKQQDCPQYAAFCNLAMARCEQTLFNAPGEALALTDAARLFLASEQETRALRAPGFDENMQAAMNCYSFAIKEMNRPGEAIIHFQRAAELQIQMPIEALLSLWEMASCKILTRDYDGALAVLSEMQHMCQERGLQLPGTNTPVGAFMDIIAKCEISRVLLLMLLEPPPQKLLPEHAQTLERYAWESFDSHSQVNFLPENVFLLLQSVVMACQEKDTESLKALQTELWPLLSAEQNHLLHLVVQERITPFGQGI", "length": 294, "header": "tr|B8A634-1|B8A634_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=f8a PE=1 SV=1 CANONICAL=A2BIC9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z3P7-1", "protein_name": "Coagulation factor VIII associated 3", "gene_name": "F8A3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLAAAGGSGPGGAGGSGPGPGPGGGDGDFLSRYRLVSAKLRRRFLRKPNVAEAAEQFAALARELRAQESLPYAAWCQLAVARCAQSLFHGPAEAAALGEAARLFLRQERDLRQRLALRGGFGEHLAAAQSCGAFAARLHLERGQPALAAGLCLELAAALRDTGRPARAAAHFQRAAELLAAAKLPLEALRCLTERASCLLLGRDYAGALAALTRAQALAGAGAGIGGSGGAAPGGAFLDALVSCEVSRVLLLLLLQPPPGKLSPEHARTLEQYCWEAPEGGAAGGGLPAAASYLPAELFLLLQSAVLACQEKDAAALRALQAELWPLLSAEQNHLLHLVLQDMLSPAGHGL", "length": 351 }, "evidence": [ { "id": "A2BIC9", "url": "https://omabrowser.org/oma/group/A2BIC9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1RZ35-1", "protein_name": "40-kDa huntingtin-associated protein", "gene_name": "", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAASAAGLGGGAGPGPESGDFLARYRQVSSKLKKRFLRKPNVAEAGEQFGQLGRELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQERDARQRLACPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRDLGQPAAAAGHFQRAAQLLLPQLPLAALQALGDAASCQLLARDYSGALAVFTRMQRLAWEHGSHPVQVPPPPPPPPPAALSQPQHQPRPPGLQPGSRAAAALPLALPPASAGSAAAPSPAALGAFSDVLVRCEVSRVLLLLLLQPPPAKLLPEHAHTLEKYSWEAFDSHGQESSGQLPEELFLLLQSLVMATHEKDTEAVKSLQVEMWPLLSAEQNHLLHLVLQETIWPSGQGI", "length": 386 }, "evidence": [ { "id": "A2BIC9", "url": "https://omabrowser.org/oma/group/A2BIC9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0RDU0-1", "protein_name": "40-kDa huntingtin-associated protein", "gene_name": "F8a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAGSASSLGGGSWPGSEAGDFLARYRQVSNKLKKRFLRKPNVAEAGEQFAQLARELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQECDARQRLGCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRAVGQPAAAAGHFQRAAQLHLPLMPLAALQALGDAASCQLLARDYTGALAVFTRMQRLAREHGGHPVQQPELPQQLPSVPQPSLPGPQPRPVLGSTLPLPLPPDHAPGSVAQSPGTLGAFADVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYSWEAFDGHGQDSSGQLPEELFLLLQSLVMAAHEKDTEGIKKLQVEMWPLLTAEQNHLLHLVLQETISPSGQGV", "length": 381 }, "evidence": [ { "id": "HGNC:3547", "url": "https://alliancegenome.org/gene/HGNC:3547#orthology", "database": "AGR" }, { "id": "HGNC:31850", "url": "https://alliancegenome.org/gene/HGNC:31850#orthology", "database": "AGR" }, { "id": "HGNC:31849", "url": "https://alliancegenome.org/gene/HGNC:31849#orthology", "database": "AGR" }, { "id": "MGI:95474", "url": "https://alliancegenome.org/gene/MGI:95474#orthology", "database": "AGR" }, { "id": "A2BIC9", "url": "https://omabrowser.org/oma/group/A2BIC9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23610-1", "protein_name": "40-kDa huntingtin-associated protein", "gene_name": "F8A3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAAGLGGGGAGPGPEAGDFLARYRLVSNKLKKRFLRKPNVAEAGEQFGQLGRELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQERDARQRLVCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRDLGQPAAAAGHFQRAAQLQLPQLPLAALQALGEAASCQLLARDYTGALAVFTRMQRLAREHGSHPVQSLPPPPPPAPQPGPGATPALPAALLPPNSGSAAPSPAALGAFSDVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYSWEAFDSHGQESSGQLPEELFLLLQSLVMATHEKDTEAIKSLQVEMWPLLTAEQNHLLHLVLQETISPSGQGV", "length": 371 }, "evidence": [ { "id": "HGNC:3547", "url": "https://alliancegenome.org/gene/HGNC:3547#orthology", "database": "AGR" }, { "id": "HGNC:31850", "url": "https://alliancegenome.org/gene/HGNC:31850#orthology", "database": "AGR" }, { "id": "HGNC:31849", "url": "https://alliancegenome.org/gene/HGNC:31849#orthology", "database": "AGR" }, { "id": "MGI:95474", "url": "https://alliancegenome.org/gene/MGI:95474#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-181#orthology", "database": "AGR" }, { "id": "A2BIC9", "url": "https://omabrowser.org/oma/group/A2BIC9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q00558-1", "protein_name": "40-kDa huntingtin-associated protein", "gene_name": "F8a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAGSASSLGGGAWPGSEAGDFLARYRQVSNKLKKRFLRKPNVAEAGEQFAQLARELRAQECLPYAAWCQLAVARCQQALFHGPGEALALTEAARLFLRQECDARQRLGCPAAYGEPLQAAASALGAAVRLHLELGQPAAAAALCLELAAALRAVGQPAAAAGHFQRAAQLHLPLMPLAALQALGDAASCQLLARDYTGALALFTRMQRLAREHGGHPVQQLELLPQPPSGPQPPLSGPQPRPVLGSTLPLPQPPDHAPGSVAPSPGTLGAFADVLVRCEVSRVLLLLLLQPPPAKLLPEHAQTLEKYSWEAFDGHGQDTSGQLPEELFLLLQSLVMAAQEKDTEGIKKLQVEMWPLLTAEQNHLLHLVLQETISPSGQGV", "length": 381 }, "evidence": [ { "id": "HGNC:3547", "url": "https://alliancegenome.org/gene/HGNC:3547#orthology", "database": "AGR" }, { "id": "HGNC:31850", "url": "https://alliancegenome.org/gene/HGNC:31850#orthology", "database": "AGR" }, { "id": "HGNC:31849", "url": "https://alliancegenome.org/gene/HGNC:31849#orthology", "database": "AGR" }, { "id": "MGI:95474", "url": "https://alliancegenome.org/gene/MGI:95474#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-181", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-181#orthology", "database": "AGR" }, { "id": "A2BIC9", "url": "https://omabrowser.org/oma/group/A2BIC9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VXR6-1", "protein_name": "Huntingtin-associated protein 40 kDa, isoform B", "gene_name": "Hap40", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDKLRGGSLGGGGSSSGAPSTAPGHEHHQLEQYQYPKNLIEQYLRASSKIKKFERAGFFKRFAPSVVDVQADFQRLAYSFEESGIQQYAAMCHIGYAKCESYGGAPQRESEAYLRAARSFLAAHNESGRLHLRTRHSGFREGAVHCYHRAADRAVDGCVFKAAILRELKQLQRQLDSTSSFASPTHQIHDLEISAETSGQRGDFRSALQHYDDIVDNVYERRGARMYGELLRRVEVLRLLLLVHLNLPPARQSPAHIKLIEYYYNLAQFESLPCSADDGGSAERPGAFVPEQQQYALAEITCAWVERKMCDLKHLLRDFGAEFGSLSDMERQLLAVMHAELARSY", "length": 345 }, "evidence": [ { "id": "HGNC:3547", "url": "https://alliancegenome.org/gene/HGNC:3547#orthology", "database": "AGR" }, { "id": "HGNC:31850", "url": "https://alliancegenome.org/gene/HGNC:31850#orthology", "database": "AGR" }, { "id": "HGNC:31849", "url": "https://alliancegenome.org/gene/HGNC:31849#orthology", "database": "AGR" }, { "id": "MGI:95474", "url": "https://alliancegenome.org/gene/MGI:95474#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "early endosome", "id": "GO:0005769", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005769", "evidence": [ { "database": "UniProtKB", "id": "A2BIC9", "url": "https://www.uniprot.org/uniprotkb/A2BIC9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "vesicle cytoskeletal trafficking", "id": "GO:0099518", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099518", "evidence": [ { "database": "UniProtKB", "id": "A2BIC9", "url": "https://www.uniprot.org/uniprotkb/A2BIC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A2BIQ6-1", "uniprot_ac": "A2BIQ6", "uniprot_id": "A2BIQ6_DANRE", "mass": { "chemical_mass": 42813.0, "monoisotopic_mass": 42813.0 }, "refseq": { "ac": "NP_001313386", "name": "uncharacterized protein LOC562347", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313386" }, "gene_names": [ { "name": "si:ch211-110p13.9", "type": "recommended", "evidence": [ { "id": "A2BIQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIQ6" } ] }, { "name": "si:ch211-110p13.9", "type": "synonym", "evidence": [ { "id": "NP_001313386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313386" } ] }, { "name": "wu:fc02a10", "type": "synonym", "evidence": [ { "id": "NP_001313386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313386" }, { "id": "A2BIQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIQ6" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC562347", "type": "synonym", "evidence": [ { "id": "A2BIQ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIQ6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC562347", "type": "synonym", "evidence": [ { "id": "NP_001313386", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313386" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01023526.1, SRR26395062.443256.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476739, SAMEA4476740 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On May 18, 2016 this sequence version replaced XP_706110.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001313386", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313386" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BIQ6", "url": "https://www.uniprot.org/uniprotkb/A2BIQ6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-110p13.9", "url": "https://www.uniprot.org/uniprotkb/A2BIQ6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-9", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000093821", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000093821", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "562347", "url": "https://www.ncbi.nlm.nih.gov/gene/562347", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:562347", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562347", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KRQSEYP", "url": "https://omabrowser.org/oma/group/KRQSEYP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2BIQ6", "url": "https://www.orthodb.org/?gene=A2BIQ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001313386", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313386", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2BIQ6", "url": "https://www.uniprot.org/uniprotkb/A2BIQ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BIQ6-1", "url": "https://www.uniprot.org/uniprotkb/A2BIQ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-9", "url": "https://zfin.org/ZDB-GENE-060526-9", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSGGVSLINMSHWESGKRRIRFLYLTNNNSFNVTKGCRNEAQMIPLFLGADLFSETDVRGENQPRYHTKYAKRGLATKLVFSSDCRFQGLRLPCSHNSLWFYSVQGVFRVAFELYSRQDQLSVMESFQDLWKSRINDDNLNMSYHLSAQDYQPQDEQEQTAIVSNDHTCSIHHDQAQRDFPPDTSSSTDHDYCSSTEQANPNQPTLLTQKLCNLAETAKLCSNIDEETTMKVLEYVERSINGMIEEEILTDAVMSLLQAHLQSFSIYSSSLLKAVAGWLGQQFNSANSTISQRVEGFKAQHIEHITNLPPPEELASQLFPEAMRNLLAHWMGLSDEAEDWKRHSEYPILLLILEFANHNLVTGVAHVLYSSLICK", "length": 376, "header": "tr|A2BIQ6-1|A2BIQ6_DANRE Isoform 1 of Uncharacterized protein LOC562347 OS=Danio rerio OX=7955 GN=si:ch211-110p13.9 PE=4 SV=2 CANONICAL=A2BIQ6-1" }, "isoforms": [ { "isoform_ac": "A2BIQ6-1", "url": "https://www.uniprot.org/uniprotkb/A2BIQ6/entry#A2BIQ6-1", "sequence": { "sequence": "MSSGGVSLINMSHWESGKRRIRFLYLTNNNSFNVTKGCRNEAQMIPLFLGADLFSETDVRGENQPRYHTKYAKRGLATKLVFSSDCRFQGLRLPCSHNSLWFYSVQGVFRVAFELYSRQDQLSVMESFQDLWKSRINDDNLNMSYHLSAQDYQPQDEQEQTAIVSNDHTCSIHHDQAQRDFPPDTSSSTDHDYCSSTEQANPNQPTLLTQKLCNLAETAKLCSNIDEETTMKVLEYVERSINGMIEEEILTDAVMSLLQAHLQSFSIYSSSLLKAVAGWLGQQFNSANSTISQRVEGFKAQHIEHITNLPPPEELASQLFPEAMRNLLAHWMGLSDEAEDWKRHSEYPILLLILEFANHNLVTGVAHVLYSSLICK", "length": 376, "header": "tr|A2BIQ6-1|A2BIQ6_DANRE Isoform 1 of Uncharacterized protein LOC562347 OS=Danio rerio OX=7955 GN=si:ch211-110p13.9 PE=4 SV=2 CANONICAL=A2BIQ6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A2BIQ6", "url": "https://www.uniprot.org/uniprotkb/A2BIQ6" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:562347", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562347", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 10, "end_pos": 12, "annotation": "n_glycosylation_sequon" }, { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 33, "end_pos": 35, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 10, "end_pos": 12 }, { "start_pos": 142, "end_pos": 144 }, { "start_pos": 288, "end_pos": 290 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 33, "end_pos": 35 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2BIR7-1", "uniprot_ac": "A2BIR7", "uniprot_id": "A2BIR7_DANRE", "mass": { "chemical_mass": 24248.0, "monoisotopic_mass": 24248.0 }, "refseq": { "ac": "NP_001003730", "name": "stromal cell-derived factor 2-like protein 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003730" }, "gene_names": [ { "name": "sdf2l1", "type": "recommended", "evidence": [ { "id": "A2BIR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ] }, { "name": "sdf2l1", "type": "synonym", "evidence": [ { "id": "NP_001003730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003730" } ] }, { "name": "wu:fc55b04", "type": "synonym", "evidence": [ { "id": "NP_001003730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003730" }, { "id": "A2BIR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ] }, { "name": "zgc:92449", "type": "synonym", "evidence": [ { "id": "NP_001003730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003730" }, { "id": "A2BIR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ] } ], "protein_names": [ { "name": "Stromal cell-derived factor 2-like protein 1 precursor", "type": "synonym", "evidence": [ { "id": "A2BIR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIR7/entry#names_and_taxonomy" } ] }, { "name": "stromal cell-derived factor 2-like protein 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001003730", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003730" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC078401.1, BC154283.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476794 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC078401.1. On Oct 7, 2011 this sequence version replaced NP_001003730.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001003730", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003730" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2BIR7", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sdf2l1", "url": "https://www.uniprot.org/uniprotkb/A2BIR7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040808-46", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040808-46", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000035631", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000035631", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23293", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23293", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "445275", "url": "https://www.ncbi.nlm.nih.gov/gene/445275", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016093", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016093", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:445275", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:445275", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KPQHGTR", "url": "https://omabrowser.org/oma/group/KPQHGTR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2BIR7", "url": "https://www.orthodb.org/?gene=A2BIR7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46809", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46809", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46809:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46809:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02815", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02815", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001003730", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003730", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2BIR7", "url": "https://www.uniprot.org/uniprotkb/A2BIR7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2BIR7-1", "url": "https://www.uniprot.org/uniprotkb/A2BIR7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040808-46", "url": "https://zfin.org/ZDB-GENE-040808-46", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMGPLRVMSVFLDLILVCLVFSPCGARDVDSSYVTCGSLVKLMNTRHSVRLHSHDVKYGSGSGQQSVTGVDSADDANSYWRIRGKPGSICQRGAPIRCGQAIRITHMTTGRNLHSHHFSSPLSNHQEVSAFGENGEGDDLDVWNVQCSATYWDREDAVRFKHTGTEVFLSVTGEQYGHPIRGQREVHGMPSPNQHNYWKVMEGVFIQPSSDPIHHDEL", "length": 218, "header": "tr|A2BIR7-1|A2BIR7_DANRE Isoform 1 of Stromal cell-derived factor 2-like protein 1 precursor OS=Danio rerio OX=7955 GN=sdf2l1 PE=1 SV=1 CANONICAL=A2BIR7-1" }, "isoforms": [ { "isoform_ac": "A2BIR7-1", "url": "https://www.uniprot.org/uniprotkb/A2BIR7/entry#A2BIR7-1", "sequence": { "sequence": "MMGPLRVMSVFLDLILVCLVFSPCGARDVDSSYVTCGSLVKLMNTRHSVRLHSHDVKYGSGSGQQSVTGVDSADDANSYWRIRGKPGSICQRGAPIRCGQAIRITHMTTGRNLHSHHFSSPLSNHQEVSAFGENGEGDDLDVWNVQCSATYWDREDAVRFKHTGTEVFLSVTGEQYGHPIRGQREVHGMPSPNQHNYWKVMEGVFIQPSSDPIHHDEL", "length": 218, "header": "tr|A2BIR7-1|A2BIR7_DANRE Isoform 1 of Stromal cell-derived factor 2-like protein 1 precursor OS=Danio rerio OX=7955 GN=sdf2l1 PE=1 SV=1 CANONICAL=A2BIR7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish gene map defines ancestral vertebrate chromosomes.", "journal": "Genome Res.", "date": "2005", "authors": "Woods Ian G, Wilson Catherine, Friedlander Brian, Chang Patricia, Reyes Daengnoy K, Nix Rebecca, Kelly Peter D, Chu Felicia, Postlethwait John H, Talbot William S", "evidence": [ { "database": "UniProtKB", "id": "A2BIR7", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ], "reference": [ { "type": "PubMed", "id": "16109975", "url": "https://glygen.org/publication/PubMed/16109975" } ] }, { "title": "RNA-sequencing analysis of TCDD-induced responses in zebrafish liver reveals high relatedness to in vivo mammalian models and conserved biological pathways.", "journal": "PLoS ONE", "date": "2013", "authors": "Li Zhi-Hua, Xu Hongyan, Zheng Weiling, Lam Siew Hong, Gong Zhiyuan", "evidence": [ { "database": "UniProtKB", "id": "A2BIR7", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ], "reference": [ { "type": "PubMed", "id": "24204792", "url": "https://glygen.org/publication/PubMed/24204792" } ] }, { "title": "Primordial germ cell migration in the yellowtail kingfish (Seriola lalandi) and identification of stromal cell-derived factor 1.", "journal": "Gen. Comp. Endocrinol.", "date": "2015", "authors": "Fern\u00e1ndez J A, Bubner E J, Takeuchi Y, Yoshizaki G, Wang T, Cummins S F, Elizur A", "evidence": [ { "database": "UniProtKB", "id": "A2BIR7", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ], "reference": [ { "type": "PubMed", "id": "25708429", "url": "https://glygen.org/publication/PubMed/25708429" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A2BIR7", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "A2BIR7", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] }, { "title": "Examining the liver-pancreas crosstalk reveals a role for the molybdenum cofactor in beta-cell regeneration.", "journal": "Life. Sci Alliance", "date": "2024", "authors": "Karampelias Christos, B\u0103loiu Bianca, Rathkolb Birgit, da Silva-Buttkus Patricia, Bachar-Wikstr\u00f6m Etty, Marschall Susan, Fuchs Helmut, Gailus-Durner Valerie, Chu Lianhe, Hrab\u011b de Angelis Martin, Andersson Olov", "evidence": [ { "database": "UniProtKB", "id": "A2BIR7", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ], "reference": [ { "type": "PubMed", "id": "39159974", "url": "https://glygen.org/publication/PubMed/39159974" } ] } ], "pathway": [ { "id": "dre:445275", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:445275", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A9Y0-1", "protein_name": "Stromal cell-derived factor 2-like 1", "gene_name": "Sdf2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGASRGLAGLTLLGLLLALSVRSGGASKASAGLVTCGSVLKLLNTHHRVRLHSHDIKYGSGSGQQSVTGVEASDDANSYWRIRGGSEGGCPRGLPVRCGQAVRLTHVLTGKNLHTHHFPSPLSNNQEVSAFGEDGEGDDLDLWTVRCSGQHWEREASVRFQHVGTSVFLSVTGEQYGNPIRGQHEVHGMPSANAHNTWKAMEGIFIKPGADPSTGHDEL", "length": 220 }, "evidence": [ { "id": "HGNC:10676", "url": "https://alliancegenome.org/gene/HGNC:10676#orthology", "database": "AGR" }, { "id": "MGI:2149842", "url": "https://alliancegenome.org/gene/MGI:2149842#orthology", "database": "AGR" }, { "id": "A2BIR7", "url": "https://omabrowser.org/oma/group/A2BIR7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3T083-1", "protein_name": "Stromal cell-derived factor 2-like protein 1", "gene_name": "SDF2L1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWSAGSGRAAGPALLGILLALSLSGGRAAKSDAGLVTCGSVLKLFNTQHRVRLHSHDIKYGSGSGQQSVTGVEASDDANSYWRIRGGTEGECPRGSPVRCGQAVRLTHVLTGKNLHTHHFPSPLTNNQEVSAFGEDGEGDDLDLWTVRCSGQHWEREAAVRFQHVGTSVFLSVTGEQYGSPIRGQHEVHGMASASAHNKWKAMEGIFIKPSPEAPGGHDEL", "length": 221 }, "evidence": [ { "id": "A2BIR7", "url": "https://omabrowser.org/oma/group/A2BIR7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q93ZE8-1", "protein_name": "Stromal cell-derived factor 2-like protein", "gene_name": "SDF2", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MALGFFCLAIFLYLSLDPDSGYTSASAAASGKEGVEITYGSAIKLMHEKTKFRLHSHDVPYGSGSGQQSVTGFPGVVDSNSYWIVKPVPGTTEKQGDAVKSGATIRLQHMKTRKWLHSHLHASPISGNLEVSCFGDDTNSDTGDHWKLIIEGSGKTWKQDQRVRLQHIDTSGYLHSHDKKYQRIAGGQQEVCGIREKKADNIWLAAEGVYLPLNESSK", "length": 218 }, "evidence": [ { "id": "A2BIR7", "url": "https://omabrowser.org/oma/group/A2BIR7/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9ESP1-1", "protein_name": "Stromal cell-derived factor 2-like protein 1", "gene_name": "Sdf2l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWGASRGRVAGPTLLGLLLALSVRSGGASKASAGLVTCGSVLKLLNTHHKVRLHSHDIKYGSGSGQQSVTGVEESDDANSYWRIRGGSEGGCPRGLPVRCGQAVRLTHVLTGKNLHTHHFPSPLSNNQEVSAFGEDGEGDDLDLWTVRCSGQHWEREASVRFQHVGTSVFLSVTGEQYGNPIRGQHEVHGMPSANAHNTWKAMEGIFIKPGADLSTGHDEL", "length": 221 }, "evidence": [ { "id": "HGNC:10676", "url": "https://alliancegenome.org/gene/HGNC:10676#orthology", "database": "AGR" }, { "id": "MGI:2149842", "url": "https://alliancegenome.org/gene/MGI:2149842#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040808-46", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040808-46#orthology", "database": "AGR" }, { "id": "A2BIR7", "url": "https://omabrowser.org/oma/group/A2BIR7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HCN8-1", "protein_name": "Stromal cell-derived factor 2-like protein 1", "gene_name": "SDF2L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWSAGRGGAAWPVLLGLLLALLVPGGGAAKTGAELVTCGSVLKLLNTHHRVRLHSHDIKYGSGSGQQSVTGVEASDDANSYWRIRGGSEGGCPRGSPVRCGQAVRLTHVLTGKNLHTHHFPSPLSNNQEVSAFGEDGEGDDLDLWTVRCSGQHWEREAAVRFQHVGTSVFLSVTGEQYGSPIRGQHEVHGMPSANTHNTWKAMEGIFIKPSVEPSAGHDEL", "length": 221 }, "evidence": [ { "id": "HGNC:10676", "url": "https://alliancegenome.org/gene/HGNC:10676#orthology", "database": "AGR" }, { "id": "MGI:2149842", "url": "https://alliancegenome.org/gene/MGI:2149842#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040808-46", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040808-46#orthology", "database": "AGR" }, { "id": "A2BIR7", "url": "https://omabrowser.org/oma/group/A2BIR7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VNA3-1", "protein_name": "MIR domain-containing protein", "gene_name": "BEST:LD29996", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQHILLLTGLALVGSISRGAATESNVVTCGSILKLLNSDYAFRLHSHDVKYGSGSGQQSVTGVEQKEDVNSHWVIKAQTGELCERGEPIACGSTVRLEHLSTKKNLHSHHFSSPLSGEQEVSAYGTDGLGDTGDHWEVVCSNENWMRSAHVRLRHIDTGMYLGMSGRSYGRPISGQMEIVGVHKPQHGTRWTTAEGLFIVPKEKSSTHDEYAHSEL", "length": 216 }, "evidence": [ { "id": "HGNC:10676", "url": "https://alliancegenome.org/gene/HGNC:10676#orthology", "database": "AGR" }, { "id": "MGI:2149842", "url": "https://alliancegenome.org/gene/MGI:2149842#orthology", "database": "AGR" }, { "id": "A2BIR7", "url": "https://omabrowser.org/oma/group/A2BIR7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "A2BIR7", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ], "pmid": "" }, { "name": "endoplasmic reticulum", "id": "GO:0005783", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005783", "evidence": [ { "database": "UniProtKB", "id": "A2BIR7", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ], "pmid": "" }, { "name": "protein-containing complex", "id": "GO:0032991", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032991", "evidence": [ { "database": "UniProtKB", "id": "A2BIR7", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A2BIR7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2BIR7" }, { "id": "PS50919", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50919" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MIR", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 85, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2CEA9-1", "uniprot_ac": "A2CEA9", "uniprot_id": "A2CEA9_DANRE", "mass": { "chemical_mass": 26313.0, "monoisotopic_mass": 26313.0 }, "refseq": { "ac": "NP_001082804", "name": "BRI3-binding protein precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082804" }, "gene_names": [ { "name": "bri3bp", "type": "recommended", "evidence": [ { "id": "A2CEA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEA9" } ] }, { "name": "bri3bp", "type": "synonym", "evidence": [ { "id": "NP_001082804", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082804" } ] }, { "name": "fa20c12", "type": "synonym", "evidence": [ { "id": "NP_001082804", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082804" }, { "id": "A2CEA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEA9" } ] }, { "name": "wu:fa20c12", "type": "synonym", "evidence": [ { "id": "NP_001082804", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082804" }, { "id": "A2CEA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEA9" } ] } ], "protein_names": [ { "name": "BRI3-binding protein precursor", "type": "synonym", "evidence": [ { "id": "NP_001082804", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082804" }, { "id": "A2CEA9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEA9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC097236.1, GFIL01002561.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA3505382 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Aug 5, 2009 this sequence version replaced XP_001339949.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001082804", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082804" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CEA9", "url": "https://www.uniprot.org/uniprotkb/A2CEA9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "bri3bp", "url": "https://www.uniprot.org/uniprotkb/A2CEA9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-5254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5254", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000010108", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000010108", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "327046", "url": "https://www.ncbi.nlm.nih.gov/gene/327046", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033367", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033367", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:327046", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:327046", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LMDTFWR", "url": "https://omabrowser.org/oma/group/LMDTFWR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2CEA9", "url": "https://www.orthodb.org/?gene=A2CEA9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31253", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31253", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31253:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31253:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14965", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14965", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001082804", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082804", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2CEA9", "url": "https://www.uniprot.org/uniprotkb/A2CEA9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2CEA9-1", "url": "https://www.uniprot.org/uniprotkb/A2CEA9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-5254", "url": "https://zfin.org/ZDB-GENE-030131-5254", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKGAKLAVVLSLFLALVLLTGAARSRKDSSTQNSFRRAASGFYQTLSNVFGEENIRALYKFFSKTTERFVHGVDSLLDTLWKLWVDLLDVMGIDSSNLTHYFSPSSVSSSPARALLLVAALLVAYWFLSLFLSGFFYILHAVFGRFFWLARVTLFALSCLYILQKFEGDPEKAVLPLCFIMAVYFMTGPVGAYWRKGGGSGTLEEKIDQLDTQIRLLNIRLSRVIETLERSSDQ", "length": 234, "header": "tr|A2CEA9-1|A2CEA9_DANRE Isoform 1 of BRI3-binding protein precursor OS=Danio rerio OX=7955 GN=bri3bp PE=1 SV=1 CANONICAL=A2CEA9-1" }, "isoforms": [ { "isoform_ac": "A2CEA9-1", "url": "https://www.uniprot.org/uniprotkb/A2CEA9/entry#A2CEA9-1", "sequence": { "sequence": "MKGAKLAVVLSLFLALVLLTGAARSRKDSSTQNSFRRAASGFYQTLSNVFGEENIRALYKFFSKTTERFVHGVDSLLDTLWKLWVDLLDVMGIDSSNLTHYFSPSSVSSSPARALLLVAALLVAYWFLSLFLSGFFYILHAVFGRFFWLARVTLFALSCLYILQKFEGDPEKAVLPLCFIMAVYFMTGPVGAYWRKGGGSGTLEEKIDQLDTQIRLLNIRLSRVIETLERSSDQ", "length": 234, "header": "tr|A2CEA9-1|A2CEA9_DANRE Isoform 1 of BRI3-binding protein precursor OS=Danio rerio OX=7955 GN=bri3bp PE=1 SV=1 CANONICAL=A2CEA9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Functional analysis of human hematopoietic stem cell gene expression using zebrafish.", "journal": "PLoS Biol.", "date": "2005", "authors": "Eckfeldt Craig E, Mendenhall Eric M, Flynn Catherine M, Wang Tzu-Fei, Pickart Michael A, Grindle Suzanne M, Ekker Stephen C, Verfaillie Catherine M", "evidence": [ { "database": "UniProtKB", "id": "A2CEA9", "url": "https://www.uniprot.org/uniprotkb/A2CEA9" } ], "reference": [ { "type": "PubMed", "id": "16089502", "url": "https://glygen.org/publication/PubMed/16089502" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A2CEA9", "url": "https://www.uniprot.org/uniprotkb/A2CEA9" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "A2CEA9", "url": "https://www.uniprot.org/uniprotkb/A2CEA9" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] }, { "title": "Quantitative Proteomics Analysis Reveals Novel Targets of miR-21 in Zebrafish Embryos.", "journal": "Sci. Rep.", "date": "2017", "authors": "Wu Ying, Lou Qi-Yong, Ge Feng, Xiong Qian", "evidence": [ { "database": "UniProtKB", "id": "A2CEA9", "url": "https://www.uniprot.org/uniprotkb/A2CEA9" } ], "reference": [ { "type": "PubMed", "id": "28642470", "url": "https://glygen.org/publication/PubMed/28642470" } ] } ], "pathway": [ { "id": "dre:327046", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:327046", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ATJ5-1", "protein_name": "BRI3 binding protein", "gene_name": "BRI3BP", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGARVSGRPRAGTGFLLLLLLLGLLAPGAQGARGRGGTEKNSYRRTVNTFSQSVSSLFGEDNVRAAQKFLTRLTERFVLGVDMFVETLWKVWAELLEVLGLDVSNLSQYFSPSSVASSPARALLLVGVVLLAYWFLSLTLGFTFSILHLVFGRFFWVVRVILFSMSCVYILHKYEGEPENAVLPLCFVVAIYFMTGPMGFYWRSSSGGPSVEEKLEQLENQVRLLNIRLNRVLDSLDRTNGK", "length": 242 }, "evidence": [ { "id": "A2CEA9", "url": "https://omabrowser.org/oma/group/A2CEA9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AHD0-1", "protein_name": "Bri3 binding protein", "gene_name": "Bri3bp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGARASQEPWARVLVGLRVLLSVLLLTLLLLSLVAPGAQGARGRGTADKNSHRRATSSFSQSVSSLFGEDNVRAAQKLLSRLTERFVQGVDMFLETLWKIWMELLEVLGLDVSNLSQYFSPASVSNSPTRALVLVGVVLLAYWFLSLTLGFTFSLLHLVFGRFFWLVRVILFSMSCVYILHKYEGEPEHAVLPLCIVVAIYFMTGPMGYWRGSAGGLCSPSVEEKLEHLENQVRLLNIRLNRVLENLDRSNEK", "length": 253 }, "evidence": [ { "id": "MGI:1924059", "url": "https://alliancegenome.org/gene/MGI:1924059#orthology", "database": "AGR" }, { "id": "HGNC:14251", "url": "https://alliancegenome.org/gene/HGNC:14251#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BXV2-1", "protein_name": "BRI3-binding protein", "gene_name": "Bri3bp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGARASQEPRTRVRAGLRVLLPVLLLALLLLALVAPGAQGARGRGAADKNSHRRATSSFSQSVSSLFGEDNVRAAQKLLSRLTERFVQGVDMFLETLWKVWMELLEVLGLDVSNLSQYFSPASVSNSPTRALVLVGVVLLAYWFLSLTLGFTFSLLHLVFGRFFWLVRVILFSMSCVYILHKYEGEPEHAVLPLCVVVAIYFMTGPMGYWRGSPGGLCSPSVEEKLEHLENQVRLLNIRLNRVLENLDRSKDK", "length": 253 }, "evidence": [ { "id": "MGI:1924059", "url": "https://alliancegenome.org/gene/MGI:1924059#orthology", "database": "AGR" }, { "id": "HGNC:14251", "url": "https://alliancegenome.org/gene/HGNC:14251#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5254#orthology", "database": "AGR" }, { "id": "A2CEA9", "url": "https://omabrowser.org/oma/group/A2CEA9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WY22-1", "protein_name": "BRI3-binding protein", "gene_name": "BRI3BP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGARASGGPLARAGLLLLLLLLLLLGLLAPGAQGARGRGGAEKNSYRRTVNTFSQSVSSLFGEDNVRAAQKFLARLTERFVLGVDMFVETLWKVWTELLDVLGLDVSNLSQYFSPASVSSSPARALLLVGVVLLAYWFLSLTLGFTFSVLHVVFGRFFWIVRVVLFSMSCVYILHKYEGEPENAVLPLCFVVAVYFMTGPMGFYWRSSPSGPSNPSNPSVEEKLEHLEKQVRLLNIRLNRVLESLDRSKDK", "length": 251 }, "evidence": [ { "id": "MGI:1924059", "url": "https://alliancegenome.org/gene/MGI:1924059#orthology", "database": "AGR" }, { "id": "HGNC:14251", "url": "https://alliancegenome.org/gene/HGNC:14251#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5254", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5254#orthology", "database": "AGR" }, { "id": "A2CEA9", "url": "https://omabrowser.org/oma/group/A2CEA9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A2CEA9", "url": "https://www.uniprot.org/uniprotkb/A2CEA9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A2CEV3-1", "uniprot_ac": "A2CEV3", "uniprot_id": "A2CEV3_DANRE", "mass": { "chemical_mass": 23566.0, "monoisotopic_mass": 23566.0 }, "refseq": { "ac": "NP_001313532", "name": "uncharacterized protein LOC796870", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313532" }, "gene_names": [ { "name": "si:dkey-220k22.3", "type": "recommended", "evidence": [ { "id": "A2CEV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEV3" } ] }, { "name": "si:dkey-220k22.3", "type": "synonym", "evidence": [ { "id": "NP_001313532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313532" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC796870", "type": "synonym", "evidence": [ { "id": "A2CEV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEV3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC796870", "type": "synonym", "evidence": [ { "id": "NP_001313532", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313532" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01037104.1, BQ284228.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA3505385 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000005.1. On May 21, 2016 this sequence version replaced XP_001334362.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001313532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313532" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CEV3", "url": "https://www.uniprot.org/uniprotkb/A2CEV3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-220k22.3", "url": "https://www.uniprot.org/uniprotkb/A2CEV3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-257", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-257", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000094693", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000094693", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "796870", "url": "https://www.ncbi.nlm.nih.gov/gene/796870", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:796870", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796870", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ITIIKWA", "url": "https://omabrowser.org/oma/group/ITIIKWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2CEV3", "url": "https://www.orthodb.org/?gene=A2CEV3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF00229", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00229", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001313532", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313532", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2CEV3", "url": "https://www.uniprot.org/uniprotkb/A2CEV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2CEV3-1", "url": "https://www.uniprot.org/uniprotkb/A2CEV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-257", "url": "https://zfin.org/ZDB-GENE-060526-257", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDTTRAARAHILCTSIALLLVLIASCLTYIFLPKVPGCKICAINASAIASIFRHQLSQEQLLLTACNHTSDSRLIWEDEWEEKRKDDESILDHNKTWIILPKEGVYLVYVQVNFNLQPQKNSTSKVEVKFQVDFDDGDREEIFSAAHDTRVVNENFQDAMLNTFLLMHMNKASNRLSVRAFPSDQLNYQPRPFSTYITIIKWADN", "length": 205, "header": "tr|A2CEV3-1|A2CEV3_DANRE Isoform 1 of Uncharacterized protein LOC796870 OS=Danio rerio OX=7955 GN=si:dkey-220k22.3 PE=3 SV=1 CANONICAL=A2CEV3-1" }, "isoforms": [ { "isoform_ac": "A2CEV3-1", "url": "https://www.uniprot.org/uniprotkb/A2CEV3/entry#A2CEV3-1", "sequence": { "sequence": "MDTTRAARAHILCTSIALLLVLIASCLTYIFLPKVPGCKICAINASAIASIFRHQLSQEQLLLTACNHTSDSRLIWEDEWEEKRKDDESILDHNKTWIILPKEGVYLVYVQVNFNLQPQKNSTSKVEVKFQVDFDDGDREEIFSAAHDTRVVNENFQDAMLNTFLLMHMNKASNRLSVRAFPSDQLNYQPRPFSTYITIIKWADN", "length": 205, "header": "tr|A2CEV3-1|A2CEV3_DANRE Isoform 1 of Uncharacterized protein LOC796870 OS=Danio rerio OX=7955 GN=si:dkey-220k22.3 PE=3 SV=1 CANONICAL=A2CEV3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:796870", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796870", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A2CEV3", "url": "https://www.uniprot.org/uniprotkb/A2CEV3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A2CEV3", "url": "https://www.uniprot.org/uniprotkb/A2CEV3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "tumor necrosis factor receptor binding", "id": "GO:0005164", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005164", "evidence": [ { "database": "UniProtKB", "id": "A2CEV3", "url": "https://www.uniprot.org/uniprotkb/A2CEV3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 67, "end_pos": 69, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A2CEV3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEV3" }, { "id": "PF00229", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00229" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "THD", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 200, "start_aa": "Trp", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 67, "end_pos": 69 }, { "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A2CEX4-1", "uniprot_ac": "A2CEX4", "uniprot_id": "A2CEX4_DANRE", "mass": { "chemical_mass": 87191.0, "monoisotopic_mass": 87191.0 }, "refseq": { "ac": "XP_005165126", "name": "activating signal cointegrator 1 complex subunit 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165126" }, "gene_names": [ { "name": "ascc2", "type": "recommended", "evidence": [ { "id": "A2CEX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEX4" } ] }, { "name": "ascc2", "type": "synonym", "evidence": [ { "id": "XP_005165126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165126" } ] }, { "name": "zgc:63666", "type": "synonym", "evidence": [ { "id": "XP_005165126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165126" }, { "id": "A2CEX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEX4" } ] } ], "protein_names": [ { "name": "Activating signal cointegrator 1 complex subunit 2 isoform X1", "type": "synonym", "evidence": [ { "id": "A2CEX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEX4/entry#names_and_taxonomy" } ] }, { "name": "activating signal cointegrator 1 complex subunit 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005165126", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165126" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005165126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165126" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CEX4", "url": "https://www.uniprot.org/uniprotkb/A2CEX4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ascc2", "url": "https://www.uniprot.org/uniprotkb/A2CEX4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040426-1223", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1223", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000013058", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000013058", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14364", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14364", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "393414", "url": "https://www.ncbi.nlm.nih.gov/gene/393414", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052586", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052586", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "LSQHEFW", "url": "https://omabrowser.org/oma/group/LSQHEFW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2CEX4", "url": "https://www.orthodb.org/?gene=A2CEX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21494", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21494", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21494:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21494:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02845", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02845", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005165126", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165126", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2CEX4", "url": "https://www.uniprot.org/uniprotkb/A2CEX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2CEX4-1", "url": "https://www.uniprot.org/uniprotkb/A2CEX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040426-1223", "url": "https://zfin.org/ZDB-GENE-040426-1223", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MACAKVPLDELHVTEHFGPQGKERTLPALHPDRKEERCFLPFKPPPEDGTPALVEEFLEHAQFISEDLDWLLALPHDKFWCQVVFDESLQGCLDSYLRHAPRGLDPFGLSSSPAVADMQRNIHRSMFMVFLRMATHKESKEHFITPAVFAEIIYNNYLFDIPKILDLCVLYGKGNSQLLHKMIDNIFTQQPSYYGDLNETIPSIIQVFDIILQKCGIQSEDTGAGQPLKLNANRCLTAMTMPEEELADLVSYMCDTCTTIHSFLDIFPEACSTFKQHNFLNRLPSFYEMAVPDLEKAVKKRNFDKSLQEDMWRRVSYSRKKMVEIAHLLLQHACLQPILEGSENVASFVEDLLQNFTTFLQEKRFLADYDEQFPLADDISLLQQAFPHLDETRTSYLLQGVESAWESVGKKRSFPSVISSSNHRAGAKSKTGRDLAASPTEGAGVSGVREELRGAEAVSYTPRKGDNGAVCTVSAGELESLLSHIRDLLPDLGEGFILACLEEYGYNSELVINNILEDKLAPSLDKLDRAMARPVKNELPPVLSTRSNVFDDDEFDVFNRDRLDMSRIWKGRRQGESVRATLDDKQHIEEQRARYQAYQTVVDEIPIANNPSGDQDNAFGLDDYDDDYDDTYDANQIGANDLDEEDELLNRRPFTIPQVLRTGKQVQEFDDDVEEDEEDKNEAVKKNHFIQDPAVLRERAEARRAAMQSRKGYRPPPASNVVGGPKGRGQTQETIQDRRRKEASKSRGANHNRRSMADRKRNKGMIPS", "length": 768, "header": "tr|A2CEX4-1|A2CEX4_DANRE Isoform 1 of Activating signal cointegrator 1 complex subunit 2 isoform X1 OS=Danio rerio OX=7955 GN=ascc2 PE=1 SV=1 CANONICAL=A2CEX4-1" }, "isoforms": [ { "isoform_ac": "A2CEX4-1", "url": "https://www.uniprot.org/uniprotkb/A2CEX4/entry#A2CEX4-1", "sequence": { "sequence": "MACAKVPLDELHVTEHFGPQGKERTLPALHPDRKEERCFLPFKPPPEDGTPALVEEFLEHAQFISEDLDWLLALPHDKFWCQVVFDESLQGCLDSYLRHAPRGLDPFGLSSSPAVADMQRNIHRSMFMVFLRMATHKESKEHFITPAVFAEIIYNNYLFDIPKILDLCVLYGKGNSQLLHKMIDNIFTQQPSYYGDLNETIPSIIQVFDIILQKCGIQSEDTGAGQPLKLNANRCLTAMTMPEEELADLVSYMCDTCTTIHSFLDIFPEACSTFKQHNFLNRLPSFYEMAVPDLEKAVKKRNFDKSLQEDMWRRVSYSRKKMVEIAHLLLQHACLQPILEGSENVASFVEDLLQNFTTFLQEKRFLADYDEQFPLADDISLLQQAFPHLDETRTSYLLQGVESAWESVGKKRSFPSVISSSNHRAGAKSKTGRDLAASPTEGAGVSGVREELRGAEAVSYTPRKGDNGAVCTVSAGELESLLSHIRDLLPDLGEGFILACLEEYGYNSELVINNILEDKLAPSLDKLDRAMARPVKNELPPVLSTRSNVFDDDEFDVFNRDRLDMSRIWKGRRQGESVRATLDDKQHIEEQRARYQAYQTVVDEIPIANNPSGDQDNAFGLDDYDDDYDDTYDANQIGANDLDEEDELLNRRPFTIPQVLRTGKQVQEFDDDVEEDEEDKNEAVKKNHFIQDPAVLRERAEARRAAMQSRKGYRPPPASNVVGGPKGRGQTQETIQDRRRKEASKSRGANHNRRSMADRKRNKGMIPS", "length": 768, "header": "tr|A2CEX4-1|A2CEX4_DANRE Isoform 1 of Activating signal cointegrator 1 complex subunit 2 isoform X1 OS=Danio rerio OX=7955 GN=ascc2 PE=1 SV=1 CANONICAL=A2CEX4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 50, "start_aa": "Thr", "end_pos": 50, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr50", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZQL9-1", "protein_name": "Activating signal cointegrator 1 complex subunit 2", "gene_name": "ASCC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPALPLDQLQITHKDLKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERATFVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEWVAPAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFLQQPSYYNDLDATVPTILQVFSNILQHCGLQGDGASAIPQKLEERSRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEIAIPELESAIKKRRLEDSKLLGDLWQRLSHSRKKLLEIFHILLNQICLLPVLESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVADDVSLLQQASSALDETRTAYILQAVESAWEGVDRRKATDARSPPAAENPNGVVETAEPENSEGEECLGAAAAPAPAVCGVELDSLISQVKDLLPELGEGFILACLEHYSYDPEQVINNVLESRLAPALSQLDRSLDRQVKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGRRKTENTRSLLNDKREVVAQRQRYEQYSVVVEEVPLQPGEGSPYHGDDYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPGEGQVEDEEEEEEEAEDEAPKPDHFVQDPAVLREKAEARRMAFLARKGYRYDSSTAVAGSPRGHGQSRETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS", "length": 743 }, "evidence": [ { "id": "A2CEX4", "url": "https://omabrowser.org/oma/group/A2CEX4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6ANY1-1", "protein_name": "Activating signal cointegrator 1 complex subunit 2", "gene_name": "Ascc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPALPLDQLQITHKDPKTGKLRTSAALHPEQKADRYFVLYKPPPKDNIPALVEEYLERANFVANDLDWLLALPHDKFWCQVIFDESLQKCLDSYLHYVPRKFDEWVAPTPEVADMQKHLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYNDLDETIPTILQVFSNILQHCGLQGDGINTIPQKLGERPRLTPSDMPLLELKDIVLYLCDTSTTLWAFLDIFPLACQTFQKHDFCYRLASFYEMAIPEIESAIKKRRLEDSKLLGDMWQRLSHSKKKLMEVFHTILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDSFFPVAEDISLLQQASSALDETRTTYILQAVEGAWEGVDRQKIKDIKDPSRAKDSNNGVTMTAEPVSEMPSQLENSEDDEECMGAAAAVGPAVSGVELDSLISQVKDLLPDLGEGFILACLEHYSYDSERVINNILEDRLAPELSQLDRSLERQVKPDPTPLLSSRHNVFQNDEFDVFSRDSVDLSRVHKGRRKEETVRSLVNDKQAVVAQWQRYQKYSVIVEEVPLQPGEYQADDYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKMPVEGQEEECDEEDEVEEEAPKPDHFIQDPAVLREKAEARRIAFLARKGYRPENSTAVTGGPRGHGQSRETTQERRKKEANKAARANHSRRTMADRKRNKGMIPS", "length": 749 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-040426-1223", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1223#orthology", "database": "AGR" }, { "id": "HGNC:24103", "url": "https://alliancegenome.org/gene/HGNC:24103#orthology", "database": "AGR" }, { "id": "RGD:1561422", "url": "https://alliancegenome.org/gene/RGD:1561422#orthology", "database": "AGR" }, { "id": "MGI:1922702", "url": "https://alliancegenome.org/gene/MGI:1922702#orthology", "database": "AGR" }, { "id": "FB:FBgn0024973", "url": "https://alliancegenome.org/gene/FB:FBgn0024973#orthology", "database": "AGR" }, { "id": "A2CEX4", "url": "https://omabrowser.org/oma/group/A2CEX4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O76912-1", "protein_name": "CUE domain-containing protein", "gene_name": "Dmel\\CG2701", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLDNDTSNNNNCNPQNLPLDELKFALSGKDGVRRNVPALDEHWVQREKPFASYLCMLSSYGRLKSGAALEEWTFAANNFRGDMEFLLSLTQHEFWSYMVYDESAMAAVVTFLQRANPYYRQTDVSRDKELDQAHLLYGQLLDLVVRLIMRLCTGKESDSEWISPKQHGSLLYSNYLISVPLLFDLLIAVGDAEPENVELLRQIFDKVLEVQPEYQKDLKEALIFYESAFLSMQIQVENEGCEGAGGGASLDVDLETPYDDVVLFAMDCAYTLRLLLLLCPQLLETIEQLRLAPSIANFYDMTVPMLYKNIYLVNPGASSLRWLNETRQQYIFIVRRVVSLQMESGRGQQLVEVMQECLSAQNFVVDYQRQFPLEHDMKLLIQRCPNIKNYEVDFVVSGYQKALASCPNGIMADDMASNGVQVTGNVQDEEFKNGDSSRTSPQPSPTANGTTRDIDLEVTAVLEVLPDLGSGFIRRLLIRYDNSEQVIAAILDDNLPPDLAQMDRQEVYIPPDPQDKQQRQTGLRHFNVHDGDRYDVLTRDQPECIIKQGKGLPGAPRNAEQLLDDKRDLKQLKERYQKYAMVEETTLERGEYDDEYDDSYEAQNEGQAPPVSLLRGRLQEAASSSAYNAQDELENDDEESSGGHSDPEPSMRTNRDFCENPEVIRARYEQRQLSKYGQKSGGHGASPSVVGAPKGQGQSQQTQRSRGQKEAHKSTRANHNRKAGAAFKRSKGMMG", "length": 735 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-040426-1223", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1223#orthology", "database": "AGR" }, { "id": "HGNC:24103", "url": "https://alliancegenome.org/gene/HGNC:24103#orthology", "database": "AGR" }, { "id": "RGD:1561422", "url": "https://alliancegenome.org/gene/RGD:1561422#orthology", "database": "AGR" }, { "id": "MGI:1922702", "url": "https://alliancegenome.org/gene/MGI:1922702#orthology", "database": "AGR" }, { "id": "FB:FBgn0024973", "url": "https://alliancegenome.org/gene/FB:FBgn0024973#orthology", "database": "AGR" }, { "id": "A2CEX4", "url": "https://omabrowser.org/oma/group/A2CEX4/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q91WR3-1", "protein_name": "Activating signal cointegrator 1 complex subunit 2", "gene_name": "Ascc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPALPLDQLQITHKDPKTGQPKTSAALNPEQKADRYFVLYKPPPKDNIPALVEEYLERANFVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLHYVPRKFDEWVAPTPEVADMQNHLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYTDLDETIPTILQVFSNILQHCGLQGDGTSTTPQKLGERSPLTPSDMPLLELKDIVLYLCDTSTTLWAFLDIFPLACQTFQKHDFCYRLASFYEMAIPELESAIKKRRLEDSKLLGDMWQRLSHSKKKLMEVFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDTFSPVAEDISLLQQASSALDETRTAYILQAVESAWEGVDRQKIKDIKDPPRAKGSNNEVTVTAEPVSEMPSQLENLEEDEECMGAAAALGPAVSGVELDSLISQVKDLLPDLGEGFILACLEHYSYDSEQVINNILEDRLAPELSQLDRGLERQVKPDPTPLLSSRHNIFQNDEFDVFSRDSVDLSRVHKGRRKEENVRSLVNDKQAVVAQWQRYQKYSVVVEEVPLQPGEYQADDYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKMPGEVQEEEWDEEDEVEEEAPKPDHFIQDPAVLREKAEARRMAFLARKGYRPENSTAVTGGPRGHGQSRETTQERRKKEANKAARANHNRRTMADRKRSKGMIPS", "length": 749 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-040426-1223", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1223#orthology", "database": "AGR" }, { "id": "HGNC:24103", "url": "https://alliancegenome.org/gene/HGNC:24103#orthology", "database": "AGR" }, { "id": "RGD:1561422", "url": "https://alliancegenome.org/gene/RGD:1561422#orthology", "database": "AGR" }, { "id": "MGI:1922702", "url": "https://alliancegenome.org/gene/MGI:1922702#orthology", "database": "AGR" }, { "id": "FB:FBgn0024973", "url": "https://alliancegenome.org/gene/FB:FBgn0024973#orthology", "database": "AGR" }, { "id": "A2CEX4", "url": "https://omabrowser.org/oma/group/A2CEX4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H1I8-1", "protein_name": "Activating signal cointegrator 1 complex subunit 2", "gene_name": "ASCC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPALPLDQLQITHKDPKTGKLRTSPALHPEQKADRYFVLYKPPPKDNIPALVEEYLERATFVANDLDWLLALPHDKFWCQVIFDETLQKCLDSYLRYVPRKFDEGVASAPEVVDMQKRLHRSVFLTFLRMSTHKESKDHFISPSAFGEILYNNFLFDIPKILDLCVLFGKGNSPLLQKMIGNIFTQQPSYYSDLDETLPTILQVFSNILQHCGLQGDGANTTPQKLEERGRLTPSDMPLLELKDIVLYLCDTCTTLWAFLDIFPLACQTFQKHDFCYRLASFYEAAIPEMESAIKKRRLEDSKLLGDLWQRLSHSRKKLMEIFHIILNQICLLPILESSCDNIQGFIEEFLQIFSSLLQEKRFLRDYDALFPVAEDISLLQQASSVLDETRTAYILQAVESAWEGVDRRKATDAKDPSVIEEPNGEPNGVTVTAEAVSQASSHPENSEEEECMGAAAAVGPAMCGVELDSLISQVKDLLPDLGEGFILACLEYYHYDPEQVINNILEERLAPTLSQLDRNLDREMKPDPTPLLTSRHNVFQNDEFDVFSRDSVDLSRVHKGKSTRKEENTRSLLNDKRAVAAQRQRYEQYSVVVEEVPLQPGESLPYHSVYYEDEYDDTYDGNQVGANDADSDDELISRRPFTIPQVLRTKVPREGQEEDDDDEEDDADEEAPKPDHFVQDPAVLREKAEARRMAFLAKKGYRHDSSTAVAGSPRGHGQSRETTQERRKKEANKATRANHNRRTMADRKRSKGMIPS", "length": 757 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-040426-1223", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1223#orthology", "database": "AGR" }, { "id": "HGNC:24103", "url": "https://alliancegenome.org/gene/HGNC:24103#orthology", "database": "AGR" }, { "id": "RGD:1561422", "url": "https://alliancegenome.org/gene/RGD:1561422#orthology", "database": "AGR" }, { "id": "MGI:1922702", "url": "https://alliancegenome.org/gene/MGI:1922702#orthology", "database": "AGR" }, { "id": "FB:FBgn0024973", "url": "https://alliancegenome.org/gene/FB:FBgn0024973#orthology", "database": "AGR" }, { "id": "A2CEX4", "url": "https://omabrowser.org/oma/group/A2CEX4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "A2CEX4", "url": "https://www.uniprot.org/uniprotkb/A2CEX4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin binding", "id": "GO:0043130", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043130", "evidence": [ { "database": "UniProtKB", "id": "A2CEX4", "url": "https://www.uniprot.org/uniprotkb/A2CEX4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A2CEX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEX4" }, { "id": "PS51140", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51140" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CUE", "eco_id": "ECO_0000259", "start_pos": 477, "end_pos": 520, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 50 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 198, "end_pos": 200 }, { "start_pos": 355, "end_pos": 357 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": 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The reference sequence was derived from JBMGRA010000013.1. 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEY7" } ] }, { "name": "si:dkey-251i10.2", "type": "synonym", "evidence": [ { "id": "NP_001313480", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313480" } ] } ], "protein_names": [ { "name": "Ferric reductase 1", "type": "recommended", "evidence": [ { "id": "A2CEY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEY7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC562682 precursor", "type": "synonym", "evidence": [ { "id": "NP_001313480", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313480" } ] } ], "function": [ { "annotation": "Ferric reductase that reduces Fe(3+) to Fe(2+) and could play a role in iron import into cells. The electron donor and therefore the reaction mechanism are not known.", "evidence": [ { "database": "UniProtKB", "id": "A2CEY7", "url": "https://www.uniprot.org/uniprotkb/A2CEY7#function" }, { "database": "UniProtKB", "id": "ARBA00094318", "url": "https://www.uniprot.org/uniprotkb/ARBA00094318#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A2CEY7", "url": "https://www.uniprot.org/uniprotkb/A2CEY7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-251i10.2", "url": "https://www.uniprot.org/uniprotkb/A2CEY7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050506-102", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050506-102", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000093957", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000093957", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08544", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08544", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "562682", "url": "https://www.ncbi.nlm.nih.gov/gene/562682", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562682", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562682", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WINVRSN", "url": "https://omabrowser.org/oma/group/WINVRSN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A2CEY7", "url": "https://www.orthodb.org/?gene=A2CEY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45828", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45828", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45828:SF32", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45828:SF32", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001313480", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313480", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A2CEY7", "url": "https://www.uniprot.org/uniprotkb/A2CEY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A2CEY7-1", "url": "https://www.uniprot.org/uniprotkb/A2CEY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050506-102", "url": "https://zfin.org/ZDB-GENE-050506-102", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMKTVFFGVVVLQFLGCVHSYGTGAPTSACGDMIPRHGVQPQPNPAPYTIQASSTKFQAGIPITVVIKGPDYKGVLLEARSGSDTTALGSWQMPPANTKFLECSGNKQGAITHSNANVKNNSTVYTWVPPATTKNIMFMATVVQQRNVFWVNVMSSSLTPSGGGTALDVNSGAERIITPALIMLIFPLAVLTV", "length": 193, "header": "tr|A2CEY7-1|A2CEY7_DANRE Isoform 1 of Ferric reductase 1 OS=Danio rerio OX=7955 GN=si:dkey-251i10.2 PE=1 SV=1 CANONICAL=A2CEY7-1" }, "isoforms": [ { "isoform_ac": "A2CEY7-1", "url": "https://www.uniprot.org/uniprotkb/A2CEY7/entry#A2CEY7-1", "sequence": { "sequence": "MMKTVFFGVVVLQFLGCVHSYGTGAPTSACGDMIPRHGVQPQPNPAPYTIQASSTKFQAGIPITVVIKGPDYKGVLLEARSGSDTTALGSWQMPPANTKFLECSGNKQGAITHSNANVKNNSTVYTWVPPATTKNIMFMATVVQQRNVFWVNVMSSSLTPSGGGTALDVNSGAERIITPALIMLIFPLAVLTV", "length": 193, "header": "tr|A2CEY7-1|A2CEY7_DANRE Isoform 1 of Ferric reductase 1 OS=Danio rerio OX=7955 GN=si:dkey-251i10.2 PE=1 SV=1 CANONICAL=A2CEY7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A2CEY7", "url": "https://www.uniprot.org/uniprotkb/A2CEY7" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "A temporal single cell transcriptome atlas of zebrafish anterior segment development.", "journal": "Sci. Rep.", "date": "2023", "authors": "V\u00f6cking Oliver, Famulski J K", "evidence": [ { "database": "UniProtKB", "id": "A2CEY7", "url": "https://www.uniprot.org/uniprotkb/A2CEY7" } ], "reference": [ { "type": "PubMed", "id": "37024546", "url": "https://glygen.org/publication/PubMed/37024546" } ] } ], "pathway": [ { "id": "dre:562682", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562682", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q9V3Y3-1", "protein_name": "Defense protein l(2)34Fc", "gene_name": "l(2)34Fc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFRLLVLAACLAISVHAYSDGAPKAACRDLTPQHGAKLQVTKPPYSISGPSHVRSDQKLTLTLGGDEFLGFMIQARDGQNRVVGQFQVVDSVHSQTLDCSGKDDTITHLSAQKGKPLTGITFDWIPPAGYKGNVKFMATVVQTGFVYWVGRVTKDIDVE", "length": 159 }, "evidence": [ { "id": "A2CEY7", "url": "https://omabrowser.org/oma/group/A2CEY7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A2CEY7", "url": "https://www.uniprot.org/uniprotkb/A2CEY7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A2CEY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A2CEY7" }, { "id": "PS51019", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51019" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Reelin", "eco_id": "ECO_0000259", "start_pos": 7, "end_pos": 175, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 121, "end_pos": 123 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A3KNJ8-1", "uniprot_ac": "A3KNJ8", "uniprot_id": "LYM5B_DANRE", "mass": { "chemical_mass": 10187.0, "monoisotopic_mass": 10187.0 }, "refseq": { "ac": "NP_001153447", "name": "LYR motif-containing protein 5B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153447" }, "gene_names": [ { "name": "lyrm5b", "type": "recommended", "evidence": [ { "id": "A3KNJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KNJ8" } ] }, { "name": "lyrm5b", "type": "synonym", "evidence": [ { "id": "NP_001153447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153447" } ] }, { "name": "wu:fb39e10", "type": "synonym", "evidence": [ { "id": "NP_001153447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153447" } ] }, { "name": "zgc:162127", "type": "synonym", "evidence": [ { "id": "NP_001153447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153447" }, { "id": "A3KNJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KNJ8" } ] } ], "protein_names": [ { "name": "LYR motif-containing protein 5B", "type": "recommended", "evidence": [ { "id": "A3KNJ8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KNJ8/entry#names_and_taxonomy" } ] }, { "name": "LYR motif-containing protein 5B", "type": "synonym", "evidence": [ { "id": "NP_001153447", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153447" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC133879.2, GFIL01025694.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505390, SAMEA4476732 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF347115.1 and BC133879.2. On May 9, 2009 this sequence version replaced XP_690260.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001153447", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153447" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KNJ8", "url": "https://www.uniprot.org/uniprotkb/A3KNJ8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "lyrm5b", "url": "https://www.uniprot.org/uniprotkb/A3KNJ8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070424-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-20", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A3KNJ8", "url": "https://alphafold.ebi.ac.uk/entry/A3KNJ8", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000045827", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000045827", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20265", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20265", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "561760", "url": "https://www.ncbi.nlm.nih.gov/gene/561760", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045296", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045296", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052000", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052000", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561760", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561760", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RGEYMAR", "url": "https://omabrowser.org/oma/group/RGEYMAR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A3KNJ8", "url": "https://www.orthodb.org/?gene=A3KNJ8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21024", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21024", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21024:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21024:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05347", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05347", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A3KNJ8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A3KNJ8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001153447", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153447", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A3KNJ8", "url": "https://www.uniprot.org/uniprotkb/A3KNJ8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KNJ8-1", "url": "https://www.uniprot.org/uniprotkb/A3KNJ8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070424-20", "url": "https://zfin.org/ZDB-GENE-070424-20", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MANPFRAEVKQLYKALLFLGREYPKGADYFRERLRAAFAKNKDMRDPDKIKQLISRGEFVVKELEALYYLRKYRALKKRYYEAE", "length": 84, "header": "sp|A3KNJ8-1|LYM5B_DANRE Isoform 1 of LYR motif-containing protein 5B OS=Danio rerio OX=7955 GN=lyrm5b PE=3 SV=1 CANONICAL=A3KNJ8-1" }, "isoforms": [ { "isoform_ac": "A3KNJ8-1", "url": "https://www.uniprot.org/uniprotkb/A3KNJ8/entry#A3KNJ8-1", "sequence": { "sequence": "MANPFRAEVKQLYKALLFLGREYPKGADYFRERLRAAFAKNKDMRDPDKIKQLISRGEFVVKELEALYYLRKYRALKKRYYEAE", "length": 84, "header": "sp|A3KNJ8-1|LYM5B_DANRE Isoform 1 of LYR motif-containing protein 5B OS=Danio rerio OX=7955 GN=lyrm5b PE=3 SV=1 CANONICAL=A3KNJ8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561760", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561760", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4AD58-1", "protein_name": "Electron transfer flavoprotein regulatory factor 1", "gene_name": "Etfrf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MANSLRGEVLTLYKNLLYLGRDYPKGADYFKRRLKNVFLKNKDVKDPEKIKELIARGEFVMKELEALYFLRKYRAMKQRYYSDTKN", "length": 86 }, "evidence": [ { "id": "RGD:2320673", "url": "https://alliancegenome.org/gene/RGD:2320673#orthology", "database": "AGR" }, { "id": "HGNC:27052", "url": "https://alliancegenome.org/gene/HGNC:27052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-20#orthology", "database": "AGR" }, { "id": "MGI:1914886", "url": "https://alliancegenome.org/gene/MGI:1914886#orthology", "database": "AGR" }, { "id": "FB:FBgn0040985", "url": "https://alliancegenome.org/gene/FB:FBgn0040985#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q503U1-1", "protein_name": "LYR motif-containing protein 5A", "gene_name": "lyrm5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTNPLRGEVIRLYKNLLYLGREYPKGTAYFRERLKTAFMKNKDVTDPEKIQKLIDRGDFVIKELEALYYLRKYRAMKKRYYEPEH", "length": 85 }, "evidence": [ { "id": "RGD:2320673", "url": "https://alliancegenome.org/gene/RGD:2320673#orthology", "database": "AGR" }, { "id": "HGNC:27052", "url": "https://alliancegenome.org/gene/HGNC:27052#orthology", "database": "AGR" }, { "id": "MGI:1914886", "url": "https://alliancegenome.org/gene/MGI:1914886#orthology", "database": "AGR" }, { "id": "FB:FBgn0040985", "url": "https://alliancegenome.org/gene/FB:FBgn0040985#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6IPR1-1", "protein_name": "Electron transfer flavoprotein regulatory factor 1", "gene_name": "ETFRF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMANSLRGEVLKLYKNLLYLGRDYPKGADYFKKRLKNIFLKNKDVKNPEKIKELIAQGEFVMKELEALYFLRKYRAMKQRYYSDTNKTN", "length": 90 }, "evidence": [ { "id": "RGD:2320673", "url": "https://alliancegenome.org/gene/RGD:2320673#orthology", "database": "AGR" }, { "id": "HGNC:27052", "url": "https://alliancegenome.org/gene/HGNC:27052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-20#orthology", "database": "AGR" }, { "id": "MGI:1914886", "url": "https://alliancegenome.org/gene/MGI:1914886#orthology", "database": "AGR" }, { "id": "FB:FBgn0040985", "url": "https://alliancegenome.org/gene/FB:FBgn0040985#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q91V16-1", "protein_name": "Electron transfer flavoprotein regulatory factor 1", "gene_name": "Etfrf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MANSLRGEVLTLYKNLLYLGRDYPKGADYFKRRLKNVFLKNKDVEDPEKIKELIARGEFVMKELEALYFLRKYRAMKQRYYSDTKV", "length": 86 }, "evidence": [ { "id": "RGD:2320673", "url": "https://alliancegenome.org/gene/RGD:2320673#orthology", "database": "AGR" }, { "id": "HGNC:27052", "url": "https://alliancegenome.org/gene/HGNC:27052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-20#orthology", "database": "AGR" }, { "id": "MGI:1914886", "url": "https://alliancegenome.org/gene/MGI:1914886#orthology", "database": "AGR" }, { "id": "FB:FBgn0040985", "url": 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"https://alliancegenome.org/gene/FB:FBgn0040985#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ8", "url": "https://www.uniprot.org/uniprotkb/A3KNJ8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of oxidative phosphorylation", "id": "GO:0090324", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090324", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ8", "url": "https://www.uniprot.org/uniprotkb/A3KNJ8" } ], "pmid": "" }, { "name": "negative regulation of cellular respiration", "id": "GO:1901856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901856", "evidence": [ { "database": "UniProtKB", "id": "A3KNJ8", "url": 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}, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A3KNR2-1", "uniprot_ac": "A3KNR2", "uniprot_id": "A3KNR2_DANRE", "mass": { "chemical_mass": 22202.0, "monoisotopic_mass": 22202.0 }, "refseq": { "ac": "NP_001038347", "name": "uncharacterized protein LOC559078", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038347" }, "gene_names": [ { "name": "si:dkey-238c7.16", "type": "recommended", "evidence": [ { "id": "A3KNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KNR2" } ] }, { "name": "fc76h06", "type": "synonym", "evidence": [ { "id": "NP_001038347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038347" }, { "id": "A3KNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KNR2" } ] }, { "name": "si:dkey-238c7.16", "type": "synonym", "evidence": [ { "id": "NP_001038347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038347" } ] }, { "name": "wu:fc76h06", "type": "synonym", "evidence": [ { "id": "NP_001038347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038347" }, { "id": "A3KNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KNR2" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC559078", "type": "synonym", "evidence": [ { "id": "A3KNR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KNR2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC559078", "type": "synonym", "evidence": [ { "id": "NP_001038347", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038347" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC133966.1, GDQH01009202.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505372, SAMEA4476737 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On Jun 16, 2025 this sequence version replaced NP_001038347.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001038347", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038347" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KNR2", "url": "https://www.uniprot.org/uniprotkb/A3KNR2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-238c7.16", "url": "https://www.uniprot.org/uniprotkb/A3KNR2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-4169", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4169", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "559078", "url": "https://www.ncbi.nlm.nih.gov/gene/559078", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:559078", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559078", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EPLVCMK", "url": "https://omabrowser.org/oma/group/EPLVCMK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A3KNR2", "url": "https://www.orthodb.org/?gene=A3KNR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001038347", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001038347", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A3KNR2", "url": "https://www.uniprot.org/uniprotkb/A3KNR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KNR2-1", "url": "https://www.uniprot.org/uniprotkb/A3KNR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-4169", "url": "https://zfin.org/ZDB-GENE-030131-4169", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGAKLSRKKSEAGIGAETADPAVAETETADGTENQEQKCCEGNKPEEEKPESSTNVLDSITQAVGETVNAVTEQIAAPVEDVVNKGIEAVESALASVSLIGKESAEQDPEQKSDPASSDVEPSLLDDLLKSPISEALISGVAVVSEAMTGETVEDKSSNPAPAEKECLDKVETPSLDLMDCKLTHETTLPDSDPSFTLEDMGQKAVDTVNLI", "length": 212, "header": "tr|A3KNR2-1|A3KNR2_DANRE Isoform 1 of Uncharacterized protein LOC559078 OS=Danio rerio OX=7955 GN=si:dkey-238c7.16 PE=1 SV=1 CANONICAL=A3KNR2-1" }, "isoforms": [ { "isoform_ac": "A3KNR2-1", "url": "https://www.uniprot.org/uniprotkb/A3KNR2/entry#A3KNR2-1", "sequence": { "sequence": "MGAKLSRKKSEAGIGAETADPAVAETETADGTENQEQKCCEGNKPEEEKPESSTNVLDSITQAVGETVNAVTEQIAAPVEDVVNKGIEAVESALASVSLIGKESAEQDPEQKSDPASSDVEPSLLDDLLKSPISEALISGVAVVSEAMTGETVEDKSSNPAPAEKECLDKVETPSLDLMDCKLTHETTLPDSDPSFTLEDMGQKAVDTVNLI", "length": 212, "header": "tr|A3KNR2-1|A3KNR2_DANRE Isoform 1 of Uncharacterized protein LOC559078 OS=Danio rerio OX=7955 GN=si:dkey-238c7.16 PE=1 SV=1 CANONICAL=A3KNR2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "A3KNR2", "url": "https://www.uniprot.org/uniprotkb/A3KNR2" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] } ], "pathway": [ { "id": "dre:559078", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559078", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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"sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A3KPI6-1", "uniprot_ac": "A3KPI6", "uniprot_id": "A3KPI6_DANRE", "mass": { "chemical_mass": 41227.0, "monoisotopic_mass": 41227.0 }, "refseq": { "ac": "XP_706416", "name": "uncharacterized protein si:ch211-288g17.3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706416" }, "gene_names": [ { "name": "si:ch211-288g17.3", "type": "recommended", "evidence": [ { "id": "A3KPI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPI6" } ] }, { "name": "si:ch211-288g17.3", "type": "synonym", "evidence": [ { "id": "XP_706416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706416" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch211-288g17.3", "type": "synonym", "evidence": [ { "id": "A3KPI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPI6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch211-288g17.3", "type": "synonym", "evidence": [ { "id": "XP_706416", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706416" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_706416", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706416" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KPI6", "url": "https://www.uniprot.org/uniprotkb/A3KPI6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-288g17.3", "url": "https://www.uniprot.org/uniprotkb/A3KPI6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-461", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-461", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000070959", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000070959", "database": "Bgee", "categories": [ "Gene 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"https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "A3KPI6", "url": "https://www.uniprot.org/uniprotkb/A3KPI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 364, "end_pos": 366 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A3KPN2-1", "uniprot_ac": "A3KPN2", "uniprot_id": "A3KPN2_DANRE", "mass": { "chemical_mass": 49276.0, "monoisotopic_mass": 49276.0 }, "refseq": { "ac": "XP_021329017", "name": "pentraxin-related protein PTX3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329017" }, "gene_names": [ { "name": "ptx3a", "type": "recommended", "evidence": [ { "id": "A3KPN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPN2" } ] }, { "name": "ptx3a", "type": "synonym", "evidence": [ { "id": "XP_021329017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329017" } ] } ], "protein_names": [ { "name": "Pentraxin-related protein PTX3", "type": "synonym", "evidence": [ { "id": "A3KPN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPN2/entry#names_and_taxonomy" } ] }, { "name": "pentraxin-related protein PTX3", "type": "synonym", "evidence": [ { "id": "XP_021329017", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329017" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329017" } ] } ], "disease": [ { "disease_id": "DOID:0050073", "recommended_name": { "id": "DOID:0050073", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050073", "name": "invasive aspergillosis", "description": "An aspergillosis that is a serious fungal infection of the lung with pneumonia caused by Aspergillus, which spreads to other parts of the body through bloodstream in patients with acute leukemia and recipients of tissue transplants. Clinical symptoms include pulmonary nodules and hemorrhage." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050073", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050073" } ] }, { "disease_id": "DOID:0050153", "recommended_name": { "id": "DOID:0050153", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050153", "name": "pulmonary aspergilloma", "description": "An aspergillosis that presents as a clump of tangled mass of Aspergillus fungus fibres, blood clots, and white blood cells, which exists in the cavities of the lungs that develop in an area of previous lung disease or lung scarring." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050153", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050153" } ] }, { "disease_id": "DOID:0050848", "recommended_name": { "id": "DOID:0050848", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050848", "name": "obstructive sleep apnea", "description": "A sleep apnea that is characterized by repeated collapse and obstruction of the upper airway during sleep, which results in reduced airflow (hypopnea) or complete airflow cessation (apnea), oxygen desaturation, and arousals from sleep." }, "synonyms": [ { "id": "DOID:0050848", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050848", "name": "obstructive sleep apnea syndrome", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "obstructive sleep apnea syndrome", "description": "Cessation of air flow during sleep due to upper airway obstruction." }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "obstructive sleep apnea", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "obstructive sleep apnea syndrome", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "Apneas, obstructive sleep", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "OSAHS", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "apnea, obstructive sleep", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "obstructive sleep Apneas", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "sleep Apneas, obstructive", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "sleep apnea hypopnea syndrome", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "sleep apnea syndrome, obstructive", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "syndrome, obstructive sleep apnea", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "syndrome, sleep apnea, obstructive", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "syndrome, upper airway resistance, sleep apnea", "description": "" }, { "id": "MONDO:0007147", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007147", "name": "upper airway resistance sleep apnea syndrome", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050848", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050848" } ] }, { "disease_id": "DOID:1003", "recommended_name": { "id": "DOID:1003", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1003", "name": "pelvic inflammatory disease", "description": "A female reproductive system disease that is characterized by an infection of the female reproductive organs." }, "synonyms": [ { "id": "DOID:1003", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1003", "name": "PID", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1003", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1003" } ] }, { "disease_id": "DOID:14115", "recommended_name": { "id": "DOID:14115", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14115", "name": "toxic shock syndrome", "description": "A commensal bacterial infectious disease that results_in infection, has_material_basis_in Streptococcus pyogenes or has_material_basis_in Staphylococcus aureus, which produce toxins that are absorbed systemically and produce the systemic manifestations. The infection has_symptom fever, has_symptom rash, has_symptom hypotension, has_symptom multiorgan failure, has_symptom desquamation, has_symptom vomiting, has_symptom diarrhea, has_symptom headache, and has_symptom nonfocal neurologic abnormalities." }, "synonyms": [ { "id": "DOID:14115", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14115", "name": "TSS", "description": "" }, { "id": "DOID:14115", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:14115", "name": "toxic shock", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "14115", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:14115" } ] }, { "disease_id": "DOID:1485", "recommended_name": { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "cystic fibrosis", "description": "A syndrome that is characterized by the buildup of thick, sticky mucus that can damage many organs." }, "synonyms": [ { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "CF", "description": "" }, { "id": "DOID:1485", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1485", "name": "mucoviscidosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis", "description": "Autosomal recessive disorder caused by pathogenic variants in the CFTR gene (cystic fibrosis transmembrane conductance regulator), which encodes a chloride and bicarbonate channel expressed in epithelial cells, and follow the diagnosis criteria. Diagnosis requires evidence of CFTR dysfunction, defined as a sweat chloride concentration of 60 mmol/L or greater, or identification of two CF-causing CFTR pathogenic variants, or an abnormal nasal potential difference measurement. CF is a progressive, multi-organ disease characterized by chronic obstructive lung disease with recurrent infections, exocrine pancreatic insufficiency, intestinal obstruction (including meconium ileus in neonates), male infertility due to obstructive azoospermia, hepatobiliary complications, and elevated sweat chloride concentrations." }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "CF", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "cystic fibrosis lung disease, modifier of", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "mucoviscidosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "pseudomonas aeruginosa, susceptibility to chronic infection by, in cystic fibrosis", "description": "" }, { "id": "MONDO:0009061", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009061", "name": "fibrocystic disease of the pancreas", "description": "" }, { "id": "MIM:219700", "resource": "MIM", "url": "https://www.omim.org/entry/219700", "name": "Cystic fibrosis", "description": "Cystic fibrosis" } ], "unlinked_id_list": [], "evidence": [ { "id": "1485", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1485" } ] }, { "disease_id": "DOID:1883", "recommended_name": { "id": "DOID:1883", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1883", "name": "hepatitis C", "description": "A viral hepatitis that results_in inflammation located_in liver, has_material_basis_in hepatitis C virus (Hepacivirus hominis), which is transmitted_by blood from an infected person enters the body of an uninfected person. The infection has_symptom fever, has_symptom fatigue, has_symptom loss of appetite, has_symptom nausea, has_symptom vomiting, has_symptom abdominal pain, has_symptom clay-colored bowel movements, has_symptom joint pain, and has_symptom jaundice." }, "synonyms": [ { "id": "DOID:1883", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1883", "name": "NANBH", "description": "" }, { "id": "DOID:1883", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1883", "name": "Viral hepatitis C", "description": "" }, { "id": "DOID:1883", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1883", "name": "chronic hepatitis C", "description": "" }, { "id": "DOID:1883", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1883", "name": "hepatitis C infection", "description": "" }, { "id": "DOID:1883", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1883", "name": "hepatitis nonA nonB", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "hepatitis C virus infection", "description": "A viral infection caused by the hepatitis C virus." }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "Hepatitis C virus caused hepatitis", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "Hepatitis C virus hepatitis", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "NANBH", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "hepatitis C infection", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "hepatitis type C", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "non-A, non-B Hepatitis", "description": "" }, { "id": "MONDO:0005231", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005231", "name": "chronic hepatitis C", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "1883", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1883" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KPN2", "url": "https://www.uniprot.org/uniprotkb/A3KPN2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ptx3a", "url": "https://www.uniprot.org/uniprotkb/A3KPN2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-8720", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8720", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "101887125", "url": "https://www.ncbi.nlm.nih.gov/gene/101887125", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001759", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001759", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030476", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030476", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042837", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042837", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058832", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058832", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101887125", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101887125", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISCDCQR", "url": "https://omabrowser.org/oma/group/ISCDCQR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR46943", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46943", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46943:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46943:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26206", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26206", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_021329017", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329017", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A3KPN2", "url": "https://www.uniprot.org/uniprotkb/A3KPN2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KPN2-1", "url": "https://www.uniprot.org/uniprotkb/A3KPN2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-8720", "url": "https://zfin.org/ZDB-GENE-030131-8720", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASKSMWTFLQTMCLVASLSMAVSDNYDDDIEVGFGHNYFNEIPDEDQLEDETPTPSPEPCKNTAFTKWDKLFTMLENSQMKENMLLQYADDIIKVELQNLRGEMIQFVAQYGGSCASAVESSVRRAGTQTESCLQNALDRAREVSADRYEQHDAVLQQLLAVSVNQAAQLDRLEKGCLKSGAFKNIQTRHLMQDVTEIENGGKLEKSLETISSELQSIREQLSLYTRSAFADKLPSGCDTGLLFPTRSSKAHAEVSPHGLLRTNAVTICLWVKPTQVFNKTILFSYSTTGNAYELQLVLSGQSASFTVDGESHLVEASGAVQEGQWGHLCASWSSQQGLASLWVNGQQAASSPGVAEGHELRSKGSILLGQEYGRHYKHLSTPDTFDAELAFTGKMTGVNMWDRVLDPKEISQQARLYGTACGIRGNVVAWGVSDIQPKEGVKLLY", "length": 447, "header": "tr|A3KPN2-1|A3KPN2_DANRE Isoform 1 of Pentraxin-related protein PTX3 OS=Danio rerio OX=7955 GN=ptx3a PE=1 SV=1 CANONICAL=A3KPN2-1" }, "isoforms": [ { "isoform_ac": "A3KPN2-1", "url": "https://www.uniprot.org/uniprotkb/A3KPN2/entry#A3KPN2-1", "sequence": { "sequence": "MASKSMWTFLQTMCLVASLSMAVSDNYDDDIEVGFGHNYFNEIPDEDQLEDETPTPSPEPCKNTAFTKWDKLFTMLENSQMKENMLLQYADDIIKVELQNLRGEMIQFVAQYGGSCASAVESSVRRAGTQTESCLQNALDRAREVSADRYEQHDAVLQQLLAVSVNQAAQLDRLEKGCLKSGAFKNIQTRHLMQDVTEIENGGKLEKSLETISSELQSIREQLSLYTRSAFADKLPSGCDTGLLFPTRSSKAHAEVSPHGLLRTNAVTICLWVKPTQVFNKTILFSYSTTGNAYELQLVLSGQSASFTVDGESHLVEASGAVQEGQWGHLCASWSSQQGLASLWVNGQQAASSPGVAEGHELRSKGSILLGQEYGRHYKHLSTPDTFDAELAFTGKMTGVNMWDRVLDPKEISQQARLYGTACGIRGNVVAWGVSDIQPKEGVKLLY", "length": 447, "header": "tr|A3KPN2-1|A3KPN2_DANRE Isoform 1 of Pentraxin-related protein PTX3 OS=Danio rerio OX=7955 GN=ptx3a PE=1 SV=1 CANONICAL=A3KPN2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 55, "start_aa": "Thr", "end_pos": 55, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr55", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:101887125", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101887125", "resource": "KEGG Pathway" }, { "id": "R-DRE-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8N7UT96-1", "protein_name": "Pentraxin-related protein PTX3 isoform X1", "gene_name": "ptx3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQRETNVHRMYAPGAVLALCLPCFLTGIVFSYEYGEDYSDSYYNEISNGDRVQSEGTQIPCPPQDLSRWDKLFIMLEDSQMKQNMLHWQTEDMVKKEMDSIRKDLHKLNNNKACVQASENTCKCISEQMNRNIKQVMEQLREAADSHQAQNNETLQQLIQLSRHQASRLAKLELGAGLGQVAVKSFSVYPKEQEASSADGGKLERALMAATADLQRVHAQLALFQRATVNRYLPSGCEMALLFPMRSKHIFAEVTPSMSMSLQTFTLCLWAKVTQALNKTVLFSYGSKINPQELQLLLSGRSLLLKVGGDTGLVEALGVVTDGQWGHFCATWSSKQGLADLWVNGESVARVSGVAEGHELPSDGFILLGQEISRSGIYRDLVSTVVFTGKMTGVNMWDHVLEAERIKEYANQDGSCDSRGNVIGWGISEIVPNGGAQYIN", "length": 440 }, "evidence": [ { "id": "HGNC:9692", "url": "https://alliancegenome.org/gene/HGNC:9692#orthology", "database": "AGR" }, { "id": "MGI:104641", "url": "https://alliancegenome.org/gene/MGI:104641#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AAA9SX10-1", "protein_name": "Pentraxin-related protein PTX3", "gene_name": "PTX3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPRFVVKTPKPRMGRPVSAENSDDYELMYVNLDNEIDNGLHPTEDPTPCDCSRENSEWDKLFTMLENSQMREGMLLQATDVMLRGELQKLQAELGRLEGSLQKLCGPEAPSETRLARALDDLLQASRDAGRRLARLEDAGALRPQEEAGRALGAVLEELRRTRADLRAVQGWAASRWLPAGCETAILFPMRSKKIFASVHPVTPMKLETFSACIWVKATEVLNKTVLFSYGTKRNPYEIQLYLSYRSIMLVVGGEENRLVADAVISLGTWTHLCSTWDSKKGHMALWVNGDSVATAVDMATGHVVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWDGVLSNEEIREAGGAESCHIRGNVVGWGVTEIQPHGGAQYVY", "length": 385 }, "evidence": [ { "id": "A3KPN2", "url": "https://omabrowser.org/oma/group/A3KPN2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LXB5-1", "protein_name": "Pentraxin-related protein PTX3", "gene_name": "Ptx3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLAETSYDYELMHVNLDNEIDNGLHPTEDPTPCDCRQEHSEWDKLFIMLENSQMREAMLLQATDDVLRGELQRLRAELGRLAGGMARPCSASGPADARLAQALEPLLQESRDANRRLARLEDAEARRHEATVPSLGAVLEELQRTRADLSAMQSWVARHWLPAGCETAIFFPMRSKKIFGSVHPVRPMKLESFSACIWVKATDVLNKTILFSYGTKWNPYEIQLYLSSQSLVFVVGGKENKLAADTVVSLGRWSHLCGTWSSEQGSMSLWANGELVATTLEMAKSHPVPEGGLLQIGQEKNGCCVGGGFDETLAFSGRITGFNIWDRVLSKEEIRASGGAESCHIRGNIVGWGVTEIQAHGGAQYVS", "length": 367 }, "evidence": [ { "id": "HGNC:9692", "url": "https://alliancegenome.org/gene/HGNC:9692#orthology", "database": "AGR" }, { "id": "MGI:104641", "url": "https://alliancegenome.org/gene/MGI:104641#orthology", "database": "AGR" }, { "id": "A3KPN2", "url": "https://omabrowser.org/oma/group/A3KPN2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H217-1", "protein_name": "Pentraxin-related protein PTX3", "gene_name": "Ptx3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MHLPAILLCAFWCAVLAETSDDYELMYVHLDNEIDNGLHPTEDPTPCDCRPEHSEWDKLFIMLENSQMREGMLLQATDDVLRGELQRLRAELGRLAGGMARPCAAGGPTDARLARVLEPLLQESRDVSRRLARLEDAEARRPEATVPGLGAVLEELQRTRADLSAVQSWLARRWLPAGCETAILFPMRSKKIFGSVHPVRPMKLESFSTCIWVKATDVLNKTILFSYGTKWNPYEIQLYLSSQSLVFVVGGKENKLTADIVVSLGRWTHLCGTWSSEQGSMSLWVNGERVATTVEMAMLHSVPEGGILQIGQEKNGCCVGGGFDETLAFSGRITGFNIWDRVLSEEEIRESGGVESCHIRGNIVGWGVTEIQPHGGAQYVS", "length": 381 }, "evidence": [ { "id": "A3KPN2", "url": "https://omabrowser.org/oma/group/A3KPN2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P26022-1", "protein_name": "Pentraxin-related protein PTX3", "gene_name": "PTX3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHLLAILFCALWSAVLAENSDDYDLMYVNLDNEIDNGLHPTEDPTPCACGQEHSEWDKLFIMLENSQMRERMLLQATDDVLRGELQRLREELGRLAESLARPCAPGAPAEARLTSALDELLQATRDAGRRLARMEGAEAQRPEEAGRALAAVLEELRQTRADLHAVQGWAARSWLPAGCETAILFPMRSKKIFGSVHPVRPMRLESFSACIWVKATDVLNKTILFSYGTKRNPYEIQLYLSYQSIVFVVGGEENKLVAEAMVSLGRWTHLCGTWNSEEGLTSLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGCCVGGGFDETLAFSGRLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYVS", "length": 381 }, "evidence": [ { "id": "HGNC:9692", "url": "https://alliancegenome.org/gene/HGNC:9692#orthology", "database": "AGR" }, { "id": "MGI:104641", "url": "https://alliancegenome.org/gene/MGI:104641#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-8720", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8720#orthology", "database": "AGR" }, { "id": "A3KPN2", "url": "https://omabrowser.org/oma/group/A3KPN2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P48759-1", "protein_name": "Pentraxin-related protein PTX3", "gene_name": "Ptx3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHLPAILLCALWSAVVAETSDDYELMYVNLDNEIDNGLHPTEDPTPCDCRQEHSEWDKLFIMLENSQMREGMLLQATDDVLRGELQRLRAELGRLAGGMARPCAAGGPADARLVRALEPLLQESRDASLRLARLEDAEARRPEATVPGLGAVLEELRRTRADLSAVQSWVARHWLPAGCETAIFFPMRSKKIFGSVHPVRPMKLESFSTCIWVKATDVLNKTILFSYGTKWNPYEIQLYLSSQSLVLVVGGKENKLAADTVVSLGRWSHLCGTWSSEQGSMSLWANGELVATTVEMAKSHSVPEGGLLQIGQEKNGCCVGGGFDESLAFSGRITGFNIWDRVLSEEEIRASGGVESCHIRGNVVGWGVTEIQAHGGAQYVS", "length": 381 }, "evidence": [ { "id": "HGNC:9692", "url": "https://alliancegenome.org/gene/HGNC:9692#orthology", "database": "AGR" }, { "id": "MGI:104641", "url": "https://alliancegenome.org/gene/MGI:104641#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-8720", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8720#orthology", "database": "AGR" }, { "id": "A3KPN2", "url": "https://omabrowser.org/oma/group/A3KPN2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A3KPN2", "url": "https://www.uniprot.org/uniprotkb/A3KPN2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "A3KPN2", "url": "https://www.uniprot.org/uniprotkb/A3KPN2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "complement component C1q complex binding", "id": "GO:0001849", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001849", "evidence": [ { "database": "UniProtKB", "id": "A3KPN2", "url": "https://www.uniprot.org/uniprotkb/A3KPN2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 280, "end_pos": 282, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A3KPN2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPN2" }, { "id": "PS51828", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51828" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pentraxin (PTX)", "eco_id": "ECO_0000259", "start_pos": 239, "end_pos": 447, "start_aa": "Cys", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 55 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 280, "end_pos": 282 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A3KPX0-1", "uniprot_ac": "A3KPX0", "uniprot_id": "A3KPX0_DANRE", "mass": { "chemical_mass": 48062.0, "monoisotopic_mass": 48062.0 }, "refseq": { "ac": "NP_001076315", "name": "uncharacterized protein C6orf136 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076315" }, "gene_names": [ { "name": "si:ch211-215a10.4", "type": "recommended", "evidence": [ { "id": "A3KPX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPX0" } ] }, { "name": "fd21a03", "type": "synonym", "evidence": [ { "id": "NP_001076315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076315" }, { "id": "A3KPX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPX0" } ] }, { "name": "si:ch211-215a10.4", "type": "synonym", "evidence": [ { "id": "NP_001076315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076315" } ] }, { "name": "wu:fd21a03", "type": "synonym", "evidence": [ { "id": "NP_001076315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076315" }, { "id": "A3KPX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPX0" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C6orf136 homolog", "type": "synonym", "evidence": [ { "id": "A3KPX0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KPX0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C6orf136 homolog", "type": "synonym", "evidence": [ { "id": "NP_001076315", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001076315" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC154247.1, GDQQ01024455.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505377 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000019.1. 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Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A3KPX0", "url": "https://www.uniprot.org/uniprotkb/A3KPX0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "A3KPX0", "url": "https://www.uniprot.org/uniprotkb/A3KPX0" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] }, { "title": "Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production.", "journal": "Mol. Brain", "date": "2019", "authors": "Newman Morgan, Hin Nhi, Pederson Stephen, Lardelli Michael", "evidence": [ { "database": "UniProtKB", "id": "A3KPX0", "url": "https://www.uniprot.org/uniprotkb/A3KPX0" } ], "reference": [ { "type": "PubMed", "id": "31053140", "url": "https://glygen.org/publication/PubMed/31053140" } ] } ], "pathway": [ { "id": "dre:565228", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565228", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LCS5-1", "protein_name": "Similar to human chromosome 6 open reading frame 136", "gene_name": "C20h6orf136", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYRPSPGAARRLRPCLRAYQDQLSPRPIPFPPLWPHSTPPTSPSFPLHRSLPPPHPPTNPLPPPLSQVQVLNSLSTVLPLRKREEGPGPDLHSGCLDGLRSLFEGPPYPHPGAVIPFQAPGTSHPSSTTPSGDQSMEEHLAVMHERLRQELPTLFLRSHDYTIYSMDVEFINEILNVRTKGRTFYVMSLTLCRFLAWNYFAQFRLEILQLTRHPENWTLQARWRLIGLPVHMLFLRFYRRDKEDLYRTFDAFSTFYLNSSGLICRHHLDKLMPSHSPSTPVKKLLVGALVALGLSEPEPSLHLCSKT", "length": 307 }, "evidence": [ { "id": "HGNC:21301", "url": "https://alliancegenome.org/gene/HGNC:21301#orthology", "database": "AGR" }, { "id": "MGI:1916912", "url": "https://alliancegenome.org/gene/MGI:1916912#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B8JJ69-1", "protein_name": "RIKEN cDNA 2310061I04 gene", "gene_name": "2310061I04Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYRPSPGAARRLGPCLRAYQARPQDQLSPRPLPFPPLWPHSTPPTSPSFPPHRSLPPSHPPTHHLPQAPPPPLSQAQALNSLSMVLPPRKREKGPGPELHSGCLDGLRSLFEGPPCPYPGAVIPFQAPGPSHSSPTTPSGDESMEEHLAVMHERLRQELPTLFLRSHDYTIYSMDVEFINEILNIRTKGRTFYVMSLTLCRFLVWNYFAQFRLEILQLTRHPENWTLQARWRLIGLPIHMLFLRFYRRDKEDLYRTFDAFSTFYLNSSGLICRHHLDKLMPSHSPSTPVKKLLVGALVALGLSEPEPSLHLCSKA", "length": 315 }, "evidence": [ { "id": "HGNC:21301", "url": "https://alliancegenome.org/gene/HGNC:21301#orthology", "database": "AGR" }, { "id": "MGI:1916912", "url": "https://alliancegenome.org/gene/MGI:1916912#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5518", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5518#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5SQH8-1", "protein_name": "Uncharacterized protein C6orf136", "gene_name": "C6orf136", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYQPSRGAARRLGPCLRAYQARPQDQLYPGTLPFPPLWPHSTTTTSPSSPLFWSPLPPRLPTQRLPQVPPLPLPQIQALSSAWVVLPPGKGEEGPGPELHSGCLDGLRSLFEGPPCPYPGAWIPFQVPGTAHPSPATPSGDPSMEEHLSVMYERLRQELPKLFLQSHDYSLYSLDVEFINEILNIRTKGRTWYILSLTLCRFLAWNYFAHLRLEVLQLTRHPENWTLQARWRLVGLPVHLLFLRFYKRDKDEHYRTYDAYSTFYLNSSGLICRHRLDKLMPSHSPPTPVKKLLVGALVALGLSEPEPDLNLCSKP", "length": 315 }, "evidence": [ { "id": "HGNC:21301", "url": "https://alliancegenome.org/gene/HGNC:21301#orthology", "database": "AGR" }, { "id": "MGI:1916912", "url": "https://alliancegenome.org/gene/MGI:1916912#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-5518", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5518#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W1F2-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG16787", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLRNFGISSIRRSSWMANWCSKERAWASAMRLSASAPAKCPQKLLNSHAANNLQQSRRAYESTKAERLPGNPKENERKPEDLDRAYEVLRTTLPKLFVEPLDYSIYSPGLIFHNNITGKHTVGLYHYVKQIAILRTVGHLKYAYVKFEVLKITKHQDDYTVRIRWRVRGISGLKVMFQFWKYKLWQLKEVLKDQEAWYDGYSVCYLGDDGLIVKHVVDKVMPDESREAVENPSATALPPGSLAATSSQKINCQ", "length": 253 }, "evidence": [ { "id": "HGNC:21301", "url": "https://alliancegenome.org/gene/HGNC:21301#orthology", "database": "AGR" }, { "id": "MGI:1916912", "url": "https://alliancegenome.org/gene/MGI:1916912#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A3KQ58-1", "uniprot_ac": "A3KQ58", "uniprot_id": "CB068_DANRE", "mass": { "chemical_mass": 19135.0, "monoisotopic_mass": 19135.0 }, "refseq": { "ac": "NP_001108165", "name": "UPF0561 protein C2orf68 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108165" }, "gene_names": [ { "name": "si:ch211-283h6.4", "type": "recommended", "evidence": [ { "id": "A3KQ58", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ58" } ] }, { "name": "si:ch211-283h6.4", "type": "synonym", "evidence": [ { "id": "NP_001108165", "database": "RefSeq", "url": 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The reference sequence was derived from JBMGRA010000005.1. On Jun 7, 2025 this sequence version replaced NP_001108165.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001108165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108165" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KQ58", "url": "https://www.uniprot.org/uniprotkb/A3KQ58" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A3KQ58", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060526-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-154", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A3KQ58", "url": "https://alphafold.ebi.ac.uk/entry/A3KQ58", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000059459", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000059459", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100001127", "url": "https://www.ncbi.nlm.nih.gov/gene/100001127", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018888", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018888", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100001127", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001127", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FCLEYEG", "url": "https://omabrowser.org/oma/group/FCLEYEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A3KQ58", "url": "https://www.orthodb.org/?gene=A3KQ58", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34256", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34256", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34256:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34256:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10573", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10573", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A3KQ58", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A3KQ58", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001108165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108165", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58JGQ2", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGQ2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KQ58", "url": "https://www.uniprot.org/uniprotkb/A3KQ58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KQ58-1", "url": "https://www.uniprot.org/uniprotkb/A3KQ58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060526-154", "url": "https://zfin.org/ZDB-GENE-060526-154", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEVIRDGEGESVKYKPGGRLDMSHGFLRHIRRNQIARDDYDREVKQAKEKQRRRHTNTPRRPRRPDRQVYNPRIRNGSEPGVNAEAEDWNESSSGTEMENTGTELFWLDYQADNGKITSFIVHKEDKPEVIVQRVAEKNVLDSSMRAALLARVGQEMNKRCDKR", "length": 164, "header": "sp|A3KQ58-1|CB068_DANRE Isoform 1 of UPF0561 protein C2orf68 homolog OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=A3KQ58-1" }, "isoforms": [ { "isoform_ac": "A0AC58JGQ2-1", "url": "https://www.uniprot.org/uniprotkb/A3KQ58/entry#A0AC58JGQ2-1", "sequence": { "sequence": "MEIIRDGEGENAKYKPGGRLDMSHGFLRHIRRNQIARDDYDREVKQAKEKQRRRHTNTPRRPRRPDRQVYNPRIRNGSEPGVNAEAEDWNESSSGTEMENTGTELFWLDYQADNGKITSIIVHKEDKPEVIVQRVAEKNVLDSSMRAALLARVGQEMNKRCDKR", "length": 164, "header": "tr|A0AC58JGQ2-1|A0AC58JGQ2_DANRE Computationally mapped isoform of UPF0561 protein C2orf68 homolog isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-283h6.4 PE=3 SV=1 CANONICAL=A3KQ58-1" }, "locus": {} }, { "isoform_ac": "A3KQ58-1", "url": "https://www.uniprot.org/uniprotkb/A3KQ58/entry#A3KQ58-1", "sequence": { "sequence": "MEVIRDGEGESVKYKPGGRLDMSHGFLRHIRRNQIARDDYDREVKQAKEKQRRRHTNTPRRPRRPDRQVYNPRIRNGSEPGVNAEAEDWNESSSGTEMENTGTELFWLDYQADNGKITSFIVHKEDKPEVIVQRVAEKNVLDSSMRAALLARVGQEMNKRCDKR", "length": 164, "header": "sp|A3KQ58-1|CB068_DANRE Isoform 1 of UPF0561 protein C2orf68 homolog OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=A3KQ58-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "A3KQ58", "url": "https://www.uniprot.org/uniprotkb/A3KQ58" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:100001127", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001127", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W7B1-1", "protein_name": "Chromosome 3 C2orf68 homolog", "gene_name": "C2orf68", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MESAPGPGPGLCYKPGGRLDMSHGFVHHIRRNQLARDDYDKKVKQAAKEKVRRRHTPAPTRPRKPDLQVYLPRHRDASTHPSNPDCEESSESSSSGGSEPEPPGHQLFCLEYEADSGDITSVIVYQDDDPGRVSDKVSAHTPLEPPMREALKLRIQEEIAKRQSRP", "length": 166 }, "evidence": [ { "id": "A3KQ58", "url": "https://omabrowser.org/oma/group/A3KQ58/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AJH9-1", "protein_name": "Similar to human chromosome 2 open reading frame 68", "gene_name": "C4h2orf68", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEAARDPGPGLCCKPGGRLDMSHGFVHHIRRNQIARDDYDKKVKQAAKEKARRRHTPAPTRPRKPDLQVYLPRHRDGSTHPVNPDCEESSESSSSGNSELEPPGRQLFCLEYEADSGEVTSVIVYQDDDPGRVSEEVSAHTPLDPAMREALRLRIQEELAKRQSRH", "length": 166 }, "evidence": [ { "id": "RGD:1587471", "url": "https://alliancegenome.org/gene/RGD:1587471#orthology", "database": "AGR" }, { "id": "MGI:1915614", "url": "https://alliancegenome.org/gene/MGI:1915614#orthology", "database": "AGR" }, { "id": "HGNC:34353", "url": "https://alliancegenome.org/gene/HGNC:34353#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-154#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HPY6-1", "protein_name": "UPF0561 protein C2orf68 homolog", "gene_name": "CUNH2orf68", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEAARDPGPGLCCKPGGRLDMSHGFVHHIRRNQIARDDYDKKVKQAAKEKARRRHTPAPTRPRKPDLQVYLPRHRDGSAHLVNPDCEESGESSSSGSSELEPPGRQLFCLEYEADSGEVTSVIVYQDDDPKRVSEEISAHTPLDPAMQEALRVRIQEELAKRQSRH", "length": 166 }, "evidence": [ { "id": "A3KQ58", "url": "https://omabrowser.org/oma/group/A3KQ58/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q149G0-1", "protein_name": "UPF0561 protein C2orf68 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAAQDHGPGLCCKPGGRLDMSHGFVHHIRRNQLDRDDYDKKVKQAAKEKARRRHTPAPTRPRKPDLQVYLPRHRDGSTHPVNPDCEEASESSSSGSSELEPPGRQLFCLDYEADSGEVTSVIVYQDDDPGRVSEAVSAHTPLDPAMREALRSRIQEELAKRQSRH", "length": 166 }, "evidence": [ { "id": "RGD:1587471", "url": "https://alliancegenome.org/gene/RGD:1587471#orthology", "database": "AGR" }, { "id": "MGI:1915614", "url": "https://alliancegenome.org/gene/MGI:1915614#orthology", "database": "AGR" }, { "id": "HGNC:34353", "url": "https://alliancegenome.org/gene/HGNC:34353#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-154#orthology", "database": "AGR" }, { "id": "A3KQ58", "url": "https://omabrowser.org/oma/group/A3KQ58/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q2NKX9-1", "protein_name": "UPF0561 protein C2orf68", "gene_name": "C2orf68", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAGPHPRPGHCCKPGGRLDMNHGFVHHIRRNQIARDDYDKKVKQAAKEKVRRRHTPAPTRPRKPDLQVYLPRHRDVSAHPRNPDYEESGESSSSGGSELEPSGHQLFCLEYEADSGEVTSVIVYQGDDPGKVSEKVSAHTPLDPPMREALKLRIQEEIAKRQSQH", "length": 166 }, "evidence": [ { "id": "RGD:1587471", "url": "https://alliancegenome.org/gene/RGD:1587471#orthology", "database": "AGR" }, { "id": "MGI:1915614", "url": "https://alliancegenome.org/gene/MGI:1915614#orthology", "database": "AGR" }, { "id": "HGNC:34353", "url": "https://alliancegenome.org/gene/HGNC:34353#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060526-154", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060526-154#orthology", "database": "AGR" }, { "id": "A3KQ58", "url": "https://omabrowser.org/oma/group/A3KQ58/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" }, { "start_pos": 90, "end_pos": 92, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 76, "end_pos": 78 }, { "start_pos": 90, "end_pos": 92 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A3KQ75-1", "uniprot_ac": "A3KQ75", "uniprot_id": "A3KQ75_DANRE", "mass": { "chemical_mass": 25401.0, "monoisotopic_mass": 25401.0 }, "refseq": { "ac": "XP_021323826", "name": "L-rhamnose-binding lectin CSL3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323826" }, "gene_names": [ { "name": "si:dkeyp-46h3.6", "type": "recommended", "evidence": [ { "id": "A3KQ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ75" } ] }, { "name": "si:dkeyp-46h3.6", "type": "synonym", "evidence": [ { "id": "XP_021323826", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323826" } ] } ], "protein_names": [ { "name": "L-rhamnose-binding lectin CSL3", "type": "synonym", "evidence": [ { "id": "XP_021323826", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323826" }, { "id": "A3KQ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ75/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021323826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323826" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KQ75", "url": "https://www.uniprot.org/uniprotkb/A3KQ75" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkeyp-46h3.6", "url": "https://www.uniprot.org/uniprotkb/A3KQ75", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-90", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000087363", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000087363", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22836", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22836", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100536038", "url": "https://www.ncbi.nlm.nih.gov/gene/100536038", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100536038", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536038", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YESTMFQ", "url": "https://omabrowser.org/oma/group/YESTMFQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A3KQ75", "url": "https://www.orthodb.org/?gene=A3KQ75", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021323826", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021323826", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A3KQ75", "url": "https://www.uniprot.org/uniprotkb/A3KQ75", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KQ75-1", "url": "https://www.uniprot.org/uniprotkb/A3KQ75-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-90", "url": "https://zfin.org/ZDB-GENE-060503-90", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFSLRAFLCLLMGCSLSAGVTLNLAPLDAEVSPRTKTMVICNGDRAVLKCAYGVLQITDANYGRTNRRDCSGRRPVLPQNTNCIFNALAPVSQSCNGLRSCELFATTDIFTDPCPDMRSYLSVTYYCLPPEIRSSAVCENAIANFKCEDGSLIHIHAANYGRTDSSTCAAGRPASQTAKTNCYASNSQTLVANVCEGKNSCSISASNGVFSDPCYGTYKYLYTAYSCVPRFYWS", "length": 234, "header": "tr|A3KQ75-1|A3KQ75_DANRE Isoform 1 of L-rhamnose-binding lectin CSL3 OS=Danio rerio OX=7955 GN=si:dkeyp-46h3.6 PE=1 SV=1 CANONICAL=A3KQ75-1" }, "isoforms": [ { "isoform_ac": "A3KQ75-1", "url": "https://www.uniprot.org/uniprotkb/A3KQ75/entry#A3KQ75-1", "sequence": { "sequence": "MFSLRAFLCLLMGCSLSAGVTLNLAPLDAEVSPRTKTMVICNGDRAVLKCAYGVLQITDANYGRTNRRDCSGRRPVLPQNTNCIFNALAPVSQSCNGLRSCELFATTDIFTDPCPDMRSYLSVTYYCLPPEIRSSAVCENAIANFKCEDGSLIHIHAANYGRTDSSTCAAGRPASQTAKTNCYASNSQTLVANVCEGKNSCSISASNGVFSDPCYGTYKYLYTAYSCVPRFYWS", "length": 234, "header": "tr|A3KQ75-1|A3KQ75_DANRE Isoform 1 of L-rhamnose-binding lectin CSL3 OS=Danio rerio OX=7955 GN=si:dkeyp-46h3.6 PE=1 SV=1 CANONICAL=A3KQ75-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100536038", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536038", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A3KQ75", "url": "https://www.uniprot.org/uniprotkb/A3KQ75" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A3KQ75", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQ75" }, { "id": "PS50228", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUEL-type lectin", "eco_id": "ECO_0000259", "start_pos": 40, "end_pos": 128, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A3KQG8-1", "uniprot_ac": "A3KQG8", "uniprot_id": "A3KQG8_DANRE", "mass": { "chemical_mass": 25986.0, "monoisotopic_mass": 25986.0 }, "refseq": { "ac": "XP_005161878", "name": "neoverrucotoxin subunit alpha", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161878" }, "gene_names": [ { "name": "zgc:171679", "type": "synonym", "evidence": [ { "id": "XP_005161878", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161878" }, { "id": "A3KQG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQG8" } ] } ], "protein_names": [ { "name": "Neoverrucotoxin subunit alpha", "type": "synonym", "evidence": [ { "id": "A3KQG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQG8/entry#names_and_taxonomy" } ] }, { "name": "neoverrucotoxin subunit alpha", "type": "synonym", "evidence": [ { "id": "XP_005161878", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161878" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005161878", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161878" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KQG8", "url": "https://www.uniprot.org/uniprotkb/A3KQG8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A3KQG8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-071004-95", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071004-95", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000071024", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000071024", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "110437713", "url": "https://www.ncbi.nlm.nih.gov/gene/110437713", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110437713", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437713", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SFYWISK", "url": "https://omabrowser.org/oma/group/SFYWISK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A3KQG8", "url": "https://www.orthodb.org/?gene=A3KQG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005161878", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161878", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A3KQG8", "url": "https://www.uniprot.org/uniprotkb/A3KQG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KQG8-1", "url": "https://www.uniprot.org/uniprotkb/A3KQG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-071004-95", "url": "https://zfin.org/ZDB-GENE-071004-95", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MENSRLRIFGLFLLIFADYYSIKVCTKDHNGETLAREELLKYACNITLDPNTAHEMLSVAEDNKTLVRNSEPMIYPDHPDRFTGLPQILCKERLSGRCYWEAEWKGLGDMVVSYGGIGRKGESLDCRFGANDKSWILSCFIGEKLIVWHDNMGVYIPLPTTPYNRIGVFLDEPAGILSFFSVPDENTLNHLYTFKTKFTEPLYAGFVLYTESVTLCDLNSFTCTITPM", "length": 228, "header": "tr|A3KQG8-1|A3KQG8_DANRE Isoform 1 of Neoverrucotoxin subunit alpha OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A3KQG8-1" }, "isoforms": [ { "isoform_ac": "A3KQG8-1", "url": "https://www.uniprot.org/uniprotkb/A3KQG8/entry#A3KQG8-1", "sequence": { "sequence": "MENSRLRIFGLFLLIFADYYSIKVCTKDHNGETLAREELLKYACNITLDPNTAHEMLSVAEDNKTLVRNSEPMIYPDHPDRFTGLPQILCKERLSGRCYWEAEWKGLGDMVVSYGGIGRKGESLDCRFGANDKSWILSCFIGEKLIVWHDNMGVYIPLPTTPYNRIGVFLDEPAGILSFFSVPDENTLNHLYTFKTKFTEPLYAGFVLYTESVTLCDLNSFTCTITPM", "length": 228, "header": "tr|A3KQG8-1|A3KQG8_DANRE Isoform 1 of Neoverrucotoxin subunit alpha OS=Danio rerio OX=7955 GN= PE=4 SV=1 CANONICAL=A3KQG8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:110437713", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437713", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A3KQG8", "url": "https://www.uniprot.org/uniprotkb/A3KQG8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "A3KQG8", "url": "https://www.uniprot.org/uniprotkb/A3KQG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A3KQG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQG8" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 225, "start_aa": "Thr", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 45, "end_pos": 47 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], 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"table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { 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Rep.", "date": "2015", "authors": "Saraiva Luis R, Ahuja Gaurav, Ivandic Ivan, Syed Adnan S, Marioni John C, Korsching Sigrun I, Logan Darren W", "evidence": [ { "database": "UniProtKB", "id": "A3KQI0", "url": "https://www.uniprot.org/uniprotkb/A3KQI0" } ], "reference": [ { "type": "PubMed", "id": "26108469", "url": "https://glygen.org/publication/PubMed/26108469" } ] }, { "title": "Overlapping but distinct topology for zebrafish V2R-like olfactory receptors reminiscent of odorant receptor spatial expression zones.", "journal": "BMC Genomics", "date": "2018", "authors": "Ahuja Gaurav, Reichel Vera, Kowatschew Daniel, Syed Adnan S, Kotagiri Aswani Kumar, Oka Yuichiro, Weth Franco, Korsching Sigrun I", "evidence": [ { "database": "UniProtKB", "id": "A3KQI0", "url": "https://www.uniprot.org/uniprotkb/A3KQI0" } ], "reference": [ { "type": "PubMed", "id": "29792162", "url": "https://glygen.org/publication/PubMed/29792162" } ] }, { "title": "Expansion of vomeronasal receptor genes (OlfC) in the evolution of fright reaction in Ostariophysan fishes.", "journal": "Commun. 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"https://www.ncbi.nlm.nih.gov/protein/NP_001018592" } ] }, { "name": "Integrator complex subunit 8", "type": "synonym", "evidence": [ { "id": "A3KQN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQN9/entry#names_and_taxonomy" } ] }, { "name": "integrator complex subunit 8", "type": "synonym", "evidence": [ { "id": "NP_001018592", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018592" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01013443.1, SRR32588723.172754.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Nov 20, 2009 this sequence version replaced NP_001018592.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001018592", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018592" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KQN9", "url": "https://www.uniprot.org/uniprotkb/A3KQN9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ints8", "url": "https://www.uniprot.org/uniprotkb/A3KQN9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050522-556", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-556", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000057986", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000057986", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "553794", "url": "https://www.ncbi.nlm.nih.gov/gene/553794", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038751", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038751", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057980", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057980", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060085", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060085", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060086", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060086", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:553794", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553794", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ASLSDWM", "url": "https://omabrowser.org/oma/group/ASLSDWM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A3KQN9", "url": "https://www.orthodb.org/?gene=A3KQN9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13350", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13350", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13350:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13350:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25756", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25756", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26722", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26722", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26725", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26725", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001018592", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001018592", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58HY54", "url": "https://www.uniprot.org/uniprotkb/A0AC58HY54", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HY54-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HY54-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HY60", "url": "https://www.uniprot.org/uniprotkb/A0AC58HY60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HY60-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HY60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HY63", "url": "https://www.uniprot.org/uniprotkb/A0AC58HY63", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HY63-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HY63-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KQN9", "url": "https://www.uniprot.org/uniprotkb/A3KQN9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KQN9-1", "url": "https://www.uniprot.org/uniprotkb/A3KQN9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050522-556", "url": "https://zfin.org/ZDB-GENE-050522-556", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSAEAADREAVSGSRPCTPPQTSWFEFLLNPSLLEQHLHSPHPDPSPVQLIFQFLEQASKPSVNEQNQVQPPVDNRRNRTLKLMALKVAAHLRWDLNMLEKGLTIPVLNMLLNELLCVSHVPPGVKHVDLDLSSLPPTTAMAVVFYNRWAIRTIVLSSFPEKQTKPGPHQLNMMNMLQQEKEHTENILSVLREQATDSIVVLEGALSIKKDFYIHTLRTLDLLAADPSTTNGETEYSTAGLRISFDHLHCQVHYDLGGIYFQQGCSDTSVYEKAREHFRKARELLTKLDFSASFCCLDEQRLAGYWSACRTLTGTSDLNESQHTPYGQISCFMRNHNYGALIEEFICDNVTLSLPNSFRHSIQLELMHKLQQGDSALEEVCNKLCVCNAVRDALEGGILSVSFHQLLLKPSKNIISFLLEVCTRSLEKENLPELSKSKMALFIKTVCDQLGDVSLAFMVSSHKLFKELLQEEEKKILMEQMRKSSDVINLSSKPLPSFYDIPASASVNISQLEQQLILSLDARHIRQILIELHGMAERPFWMVNTKWEVPVDYVNVILAIKDKLTRDLVYILLAKGLHCINITDFVHACQLFTACLELVTEFSPKLRQVMLNELLLMEVRAHEEGTAKGRIVRPPPDLVSRVRGYLEMRIHDLPLRQTVGEECVVFMLNWRENEYLTLQVPQSLVNNNPYIKLGHLIASTCKELPGPKESRRTAKELWEVVVQICSFSSQHKRTSDSRVSLLKQRESSLGILPRSKFITFVKKIREPLVLTTLISLFVRLHSIVRDDIVNEVTAEHISIWPSSLTNLQSVDVDAVVITLKELVNYALSLNPNNQSWLCTQADIYFVTNQYSTAMHYYLQAGTVCSDFFTKPVPPDVYTDQVLKRMIKCCSLLNCHTQVAVLCQFLREVDYMTAFKALQEQNSHDSMDSFYDYIWDVTILEYLTYIHHKRGESDKRQVAIKAIGRNELNSSNPEEVMQLAAQKRKKRFLQAMAKLYF", "length": 996, "header": "tr|A3KQN9-1|A3KQN9_DANRE Isoform 1 of Integrator complex subunit 8 OS=Danio rerio OX=7955 GN=ints8 PE=1 SV=1 CANONICAL=A3KQN9-1" }, "isoforms": [ { "isoform_ac": "A0AC58HY54-1", "url": "https://www.uniprot.org/uniprotkb/A3KQN9/entry#A0AC58HY54-1", "sequence": { "sequence": "MRNHNYGALIEEFICDNVTLSLPNSFRHSIQLELMHKLQQGDSALEEVCNKLCVCNAVRDALEGGILSVSFHQLLLKPSKNIISFLLEVCTRSLEKENLPELSKSKMALFIKTVCDQLGDVSLAFMVSSHKLFKELLQEEEKKILMEQMRKSSDVINLSSKPLPSFYDIPASASVNISQLEQQLILSLDARHIRQILIELHGMAERPFWMVNTKWEVPVDYVNVILAIKDKLTRDLVYILLAKGLHCINITDFVHACQLFTACLELVTEFSPKLRQVMLNELLLMEVRAHEEGTAKGRIVRPPPDLVSRVRGYLEMRIHDLPLRQTVGEECVVFMLNWRENEYLTLQVPQSLVNNNPYIKLGHLIASTCKELPGPKESRRTAKELWEVVVQICSFSSQHKRTSDSRVSLLKQRESSLGILPRSKFITFVKKIREPLVLTTLISLFVRLHSIVRDDIVNEVTAEHISIWPSSLTNLQSVDVDAVVITLKELVNYALSLNPNNQSWLCTQADIYFVTNQYSTAMHYYLQAGTVCSDFFTKPVPPDVYTDQVLKRMIKCCSLLNCHTQVAVLCQFLREVDYMTAFKALQEQNSHDSMDSFYDYIWDVTILEYLTYIHHKRGESDKRQVAIKAIGRNELNSSNPEEVMQLAAQKRKKRFLQAMAKLYF", "length": 664, "header": "tr|A0AC58HY54-1|A0AC58HY54_DANRE Computationally mapped isoform of Integrator complex subunit 8 isoform X1 OS=Danio rerio OX=7955 GN=ints8 PE=1 SV=1 CANONICAL=A3KQN9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HY60-1", "url": "https://www.uniprot.org/uniprotkb/A3KQN9/entry#A0AC58HY60-1", "sequence": { "sequence": "MHKLQQGDSALEEVCNKLCVCNAVRDALEGGILSVSFHQLLLKPSKNIISFLLEVCTRSLEKENLPELSKSKMALFIKTVCDQLGDVSLAFMVSSHKLFKELLQEEEKKILMEQMRKSSDVINLSSKPLPSFYDIPASASVNISQLEQQLILSLDARHIRQILIELHGMAERPFWMVNTKWEVPVDYVNVILAIKDKLTRDLVYILLAKGLHCINITDFVHACQLFTACLELVTEFSPKLRQVMLNELLLMEVRAHEEGTAKGRIVRPPPDLVSRVRGYLEMRIHDLPLRQTVGEECVVFMLNWRENEYLTLQVPQSLVNNNPYIKLGHLIASTCKELPGPKESRRTAKELWEVVVQICSFSSQHKRTSDSRVSLLKQRESSLGILPRSKFITFVKKIREPLVLTTLISLFVRLHSIVRDDIVNEVTAEHISIWPSSLTNLQSVDVDAVVITLKELVNYALSLNPNNQSWLCTQADIYFVTNQYSTAMHYYLQAGTVCSDFFTKPVPPDVYTDQVLKRMIKCCSLLNCHTQVAVLCQFLREVDYMTAFKALQEQNSHDSMDSFYDYIWDVTILEYLTYIHHKRGESDKRQVAIKAIGRNELNSSNPEEVMQLAAQKRKKRFLQAMAKLYF", "length": 630, "header": "tr|A0AC58HY60-1|A0AC58HY60_DANRE Computationally mapped isoform of Integrator complex subunit 8 isoform X2 OS=Danio rerio OX=7955 GN=ints8 PE=1 SV=1 CANONICAL=A3KQN9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HY63-1", "url": "https://www.uniprot.org/uniprotkb/A3KQN9/entry#A0AC58HY63-1", "sequence": { "sequence": "MVSSHKLFKELLQEEEKKILMEQMRKSSDVINLSSKPLPSFYDIPASASVNISQLEQQLILSLDARHIRQILIELHGMAERPFWMVNTKWEVPVDYVNVILAIKDKLTRDLVYILLAKGLHCINITDFVHACQLFTACLELVTEFSPKLRQVMLNELLLMEVRAHEEGTAKGRIVRPPPDLVSRVRGYLEMRIHDLPLRQTVGEECVVFMLNWRENEYLTLQVPQSLVNNNPYIKLGHLIASTCKELPGPKESRRTAKELWEVVVQICSFSSQHKRTSDSRVSLLKQRESSLGILPRSKFITFVKKIREPLVLTTLISLFVRLHSIVRDDIVNEVTAEHISIWPSSLTNLQSVDVDAVVITLKELVNYALSLNPNNQSWLCTQADIYFVTNQYSTAMHYYLQAGTVCSDFFTKPVPPDVYTDQVLKRMIKCCSLLNCHTQVAVLCQFLREVDYMTAFKALQEQNSHDSMDSFYDYIWDVTILEYLTYIHHKRGESDKRQVAIKAIGRNELNSSNPEEVMQLAAQKRKKRFLQAMAKLYF", "length": 539, "header": "tr|A0AC58HY63-1|A0AC58HY63_DANRE Computationally mapped isoform of Integrator complex subunit 8 isoform X3 OS=Danio rerio OX=7955 GN=ints8 PE=1 SV=1 CANONICAL=A3KQN9-1" }, "locus": {} }, { "isoform_ac": "A3KQN9-1", "url": "https://www.uniprot.org/uniprotkb/A3KQN9/entry#A3KQN9-1", "sequence": { "sequence": "MSAEAADREAVSGSRPCTPPQTSWFEFLLNPSLLEQHLHSPHPDPSPVQLIFQFLEQASKPSVNEQNQVQPPVDNRRNRTLKLMALKVAAHLRWDLNMLEKGLTIPVLNMLLNELLCVSHVPPGVKHVDLDLSSLPPTTAMAVVFYNRWAIRTIVLSSFPEKQTKPGPHQLNMMNMLQQEKEHTENILSVLREQATDSIVVLEGALSIKKDFYIHTLRTLDLLAADPSTTNGETEYSTAGLRISFDHLHCQVHYDLGGIYFQQGCSDTSVYEKAREHFRKARELLTKLDFSASFCCLDEQRLAGYWSACRTLTGTSDLNESQHTPYGQISCFMRNHNYGALIEEFICDNVTLSLPNSFRHSIQLELMHKLQQGDSALEEVCNKLCVCNAVRDALEGGILSVSFHQLLLKPSKNIISFLLEVCTRSLEKENLPELSKSKMALFIKTVCDQLGDVSLAFMVSSHKLFKELLQEEEKKILMEQMRKSSDVINLSSKPLPSFYDIPASASVNISQLEQQLILSLDARHIRQILIELHGMAERPFWMVNTKWEVPVDYVNVILAIKDKLTRDLVYILLAKGLHCINITDFVHACQLFTACLELVTEFSPKLRQVMLNELLLMEVRAHEEGTAKGRIVRPPPDLVSRVRGYLEMRIHDLPLRQTVGEECVVFMLNWRENEYLTLQVPQSLVNNNPYIKLGHLIASTCKELPGPKESRRTAKELWEVVVQICSFSSQHKRTSDSRVSLLKQRESSLGILPRSKFITFVKKIREPLVLTTLISLFVRLHSIVRDDIVNEVTAEHISIWPSSLTNLQSVDVDAVVITLKELVNYALSLNPNNQSWLCTQADIYFVTNQYSTAMHYYLQAGTVCSDFFTKPVPPDVYTDQVLKRMIKCCSLLNCHTQVAVLCQFLREVDYMTAFKALQEQNSHDSMDSFYDYIWDVTILEYLTYIHHKRGESDKRQVAIKAIGRNELNSSNPEEVMQLAAQKRKKRFLQAMAKLYF", "length": 996, "header": "tr|A3KQN9-1|A3KQN9_DANRE Isoform 1 of Integrator complex subunit 8 OS=Danio rerio OX=7955 GN=ints8 PE=1 SV=1 CANONICAL=A3KQN9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A3KQN9", "url": "https://www.uniprot.org/uniprotkb/A3KQN9" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Biallelic sequence variants in INTS1 in patients with developmental delays, cataracts, and craniofacial anomalies.", "journal": "Eur. J. Hum. Genet.", "date": "2019", "authors": "Krall M, Htun S, Schnur RE, Brooks AS, Baker L, de Alba Campomanes A, Lamont RE, Gripp KW, Schneidman-Duhovny D, Innes AM, Mancini GMS, Slavotinek AM", "evidence": [ { "database": "UniProtKB", "id": "A3KQN9", "url": "https://www.uniprot.org/uniprotkb/A3KQN9" } ], "reference": [ { "type": "PubMed", "id": "30622326", "url": "https://glygen.org/publication/PubMed/30622326" } ] } ], "pathway": [ { "id": "dre:553794", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:553794", "resource": "KEGG Pathway" }, { "id": "R-DRE-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5P482-1", "protein_name": "Integrator complex subunit 8", "gene_name": "INTS8", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSAEAADREAATSSRPCTPPQTSWFEFLLEEDLLEQHLRKPSPDPPPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRILKLLALKVAAHLKWDLDVLEKSLSVPVLNMLLNELLCISKVPPGTKHVDVDLSSLPPTTAMAILLYNRWAIRTIVKSSFPVKQVKPGPPQLNVMNQMQQEKELTENILKVLKEQAADSILVLEGALKLNKDLYVHTIRTLDLLAMEPGMVNGETESSTAGLKISAEEIQCQVCYDLGAIYFQQGATNAALHENAKEKFFKTKELIAKIGSSSLHCTIDEKRLAGYCQACGVLTSSDDDASQQTTPYNQIHNCMKSGNYQDLVKIFLEDNLALSLPVQFRQSVLRELFQKAQQGNDALDEVCFKICVCNTVCDVLQGQIIDIQFCQLFLKPNKEKIDFLLEVCSRSINLETASESLKRKMAAFLKNLCLGLEDLQLVFMISSHELFIKLLKDDERKLLVDQMRKRSLRINLSTKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTISNKWEVPNVYGNVILGIKDNLTRDLVYILMAKGLHCCAIKDFVHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIYTHEAGAGAAGERPPSDLISRVRGYLEMRVPDIPLRQVIAEECVAFLLNWRENEYLTMQVPLPLVQTNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSNQHKRGNDGRVSLIKHRESTLGIMYRSELLSFIKKLREPLVLTTILSLFVKLHNVREDIVNDITAEYISIWPSSIPNLQSVDFEAVAVTVKELVNYALTINSNNHFWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKMVPPDVFTDQVIKRMIKCCSLLNCHTQVAILCQFLREVDYKTAFKALQEQNSHDAMDSYYEYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF", "length": 995 }, "evidence": [ { "id": "A3KQN9", "url": "https://omabrowser.org/oma/group/A3KQN9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A1ZAK1-1", "protein_name": "Integrator complex subunit 8", "gene_name": "IntS8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDDPLKPKPVPLAAETVLWFEFLLDPHKITQHLQRPHPEPSAMELIVQFISMTPNTAQESVGTPGSDLQNLNQTPSNSGPIPGVVGGAPAPTTPTASGGVGMPHSPQRPAEKGLQLNRKQLALKILELKVATWLKWDLDALEKNLPVIMQLALLRDLCTISYGCSLSIPLPNDFDARISAAGNERAARFALTIYHRMLLRMQLIKEQALKAPRPQNTMYQTVDQLQQFLDTPTQPSIEYLQQLCASTKPFYIFHYDSFVPLRCDDIGNGQNYDVMHLITPQELRAQLHYELAQYYLYTKQYVLAREAAAACNTNLQAIPPQTTLYYCHIRPSELEGLLQACGISAEEQSLLEKFQQSLLNNYTDIVSILRMDNRRREIPFISRRQVELDIEGSISTGILKETVQLQLQVAALNVVRNIFEWGSIFGSVEYFEKYRELDCLPPLVEALQEMLPHCTFKEQAALKHFLIDCLLHQGGQSRQLLQTVRGFGLFSSDELQDIDEQMLQATPPVPTNSLASLSDWMCHSKMSRVDVGALERQLISCTNANTVRILLVKLCATAPGKPLWAINPSWDVPQPLKTLIMAMPVSFLQDFSYVLLGKARELATRGNYIDAVSMLSVLKSENQRQEMAANVQLMCKLITWEILHIQITQCLEEWHQKPLDLQSLGGRCKQCLGALQAGDSIVPRPDILESCAIMLLNLTEFPPLLYLDKRAGPLELPLAFAATFIEMEKMKGPKKVCRDAWELMLSMFLNVPKRGSSGVGGISSLQAFLQRIRHQSVFGLAISMIGKVHNILKDDPNHDLSCEYMQLWPTSINNPVSYSLRSVCETLQWLLSEALSYYPQTISWLKMKGDLDLAIGNNESAMRCYVNALVTGTDYCTMPLQRNVADDYVIRKMIRCAANLGCHMQATVLCQFLDEIDYGIVFKNLSEKSSNFTDAMDAYYSCIWDTTLLEFIVNLHAKRGEHSRKLEAISMMGTLELNANNNEEIKRESAMVRKSRFLRALAKQYLL", "length": 1007 }, "evidence": [ { "id": "HGNC:26048", "url": "https://alliancegenome.org/gene/HGNC:26048#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-556", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-556#orthology", "database": "AGR" }, { "id": "MGI:1919906", "url": "https://alliancegenome.org/gene/MGI:1919906#orthology", "database": "AGR" }, { "id": "RGD:1310592", "url": "https://alliancegenome.org/gene/RGD:1310592#orthology", "database": "AGR" }, { "id": "FB:FBgn0289323", "url": "https://alliancegenome.org/gene/FB:FBgn0289323#orthology", "database": "AGR" }, { "id": "A3KQN9", "url": "https://omabrowser.org/oma/group/A3KQN9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZLQ6-1", "protein_name": "Integrator complex subunit 8", "gene_name": "Ints8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSAEAADREAATSSRPCTPPQTCWFEFLLEESLLEKHLRKACPDPAPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRSLKLLALKVAAHLKWDLDILEKSLSVPVLNMLLNELLCVSKVPPGTKHVDVDLAALPPTTAMAILLYNRWAIRTIVQSSFPVKQAKPGPPQLNVMNQMQQEKELTENILKVLREQAADSILVLEAALKLNKDLYVHTMRTLDLLAVEPGTVNGETENSTAGLKIRTEEMQCQVCYDLGAAYFQQGSTNSAAYESAREKFFRTKELIAEIGSLSLHCTIDEKRLAGYCQACDVLVPSSDTNSQQVTPYSQVHICLRSGSYQEVVQIFIEDNVTFTLPVQFRQSVLRELFQKAQQGNEALDEICFKICSCNTVRDILEGRTISVQFNQLFLRPNKEKIDFLLEVCSRSIDIEKASDSLKGNMAAFLKNVCLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSTVILGIKDNLTRDLVYILMAKGLHCSTVKDFPHSKQLFTAGLELVTEFSPKLRQVMLNEILLLDILTHEAGVGHSGERPPSDLISRVRGYLEMRLPDIPLRQVVAAECVAFMLNWRENEYLTLQVPAFLFQNNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSNQHKRGNDGRVSLIKQRESTLGIMYRSELLSFIKKLREPLVLTIILSLFVKLHNVREDIVNDITAEHISIWPSSIPNLQSVDFEAVAITVREVVRYALSVNPNSHAWLIIQADIYFATNQHSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF", "length": 978 }, "evidence": [ { "id": "HGNC:26048", "url": "https://alliancegenome.org/gene/HGNC:26048#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-556", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-556#orthology", "database": "AGR" }, { "id": "MGI:1919906", "url": "https://alliancegenome.org/gene/MGI:1919906#orthology", "database": "AGR" }, { "id": "RGD:1310592", "url": "https://alliancegenome.org/gene/RGD:1310592#orthology", "database": "AGR" }, { "id": "FB:FBgn0289323", "url": "https://alliancegenome.org/gene/FB:FBgn0289323#orthology", "database": "AGR" }, { "id": "A3KQN9", "url": "https://omabrowser.org/oma/group/A3KQN9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q75QN2-1", "protein_name": "Integrator complex subunit 8", "gene_name": "INTS8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSAEAADREAATSSRPCTPPQTCWFEFLLEESLLEKHLRKPCPDPAPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRILKLLALKVAAHLKWDLDILEKSLSVPVLNMLLNELLCISKVPPGTKHVDMDLATLPPTTAMAVLLYNRWAIRTIVQSSFPVKQAKPGPPQLSVMNQMQQEKELTENILKVLKEQAADSILVLEAALKLNKDLYVHTMRTLDLLAMEPGMVNGETESSTAGLKVKTEEMQCQVCYDLGAAYFQQGSTNSAVYENAREKFFRTKELIAEIGSLSLHCTIDEKRLAGYCQACDVLVPSSDSTSQQLTPYSQVHICLRSGNYQEVIQIFIEDNLTLSLPVQFRQSVLRELFKKAQQGNEALDEICFKVCACNTVRDILEGRTISVQFNQLFLRPNKEKIDFLLEVCSRSVNLEKASESLKGNMAAFLKNVCLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSGVILGIKDNLTRDLVYILMAKGLHCSTVKDFSHAKQLFAACLELVTEFSPKLRQVMLNEMLLLDIHTHEAGTGQAGERPPSDLISRVRGYLEMRLPDIPLRQVIAEECVAFMLNWRENEYLTLQVPAFLLQSNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSSQHKRGNDGRVSLIKQRESTLGIMYRSELLSFIKKLREPLVLTIILSLFVKLHNVREDIVNDITAEHISIWPSSIPNLQSVDFEAVAITVKELVRYTLSINPNNHSWLIIQADIYFATNQYSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVIKRMIKCCSLLNCHTQVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF", "length": 995 }, "evidence": [ { "id": "HGNC:26048", "url": "https://alliancegenome.org/gene/HGNC:26048#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-556", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-556#orthology", "database": "AGR" }, { "id": "MGI:1919906", "url": "https://alliancegenome.org/gene/MGI:1919906#orthology", "database": "AGR" }, { "id": "RGD:1310592", "url": "https://alliancegenome.org/gene/RGD:1310592#orthology", "database": "AGR" }, { "id": "FB:FBgn0289323", "url": "https://alliancegenome.org/gene/FB:FBgn0289323#orthology", "database": "AGR" }, { "id": "A3KQN9", "url": "https://omabrowser.org/oma/group/A3KQN9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80V86-1", "protein_name": "Integrator complex subunit 8", "gene_name": "Ints8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSAEAADREAATSSRPCTPPQTCWFEFLLEESLLEKHLRKACPDPAPVQLIVQFLEQASKPSVNEQNQVQPPPDNKRNRVLKLLALKVAAHLKWDLDILEKSLSVPVLNMLLNELLCISKVPPGTKHVDMDLSALPPTTAMAILLYNRWAIRTIVQSSFPVKQAKPGPPQLNVMNQMQQEKELTENILKVLKEQAADCILVLEAALRLNKDLYVHTMRTLDLLAVEPGTVNGETENSTAGLKIRTEEMQCQVCYDLGAAYFQQGSTDSAIYENAREKFFRTKELLAEIGSLSLHCTIDEKRLAGYCQACDVLVPSSDNNSQQLTPYSQVHICLRSGSYQEVVQIFIEDNLTFTLPVQFRQSVLRELFQKAQQGNEALDEICFKICVCNTVRDVLEGRTISVQFNQLFLRPNKEKIDFLLEVCSRSINVEKASDSLKGNMAAFLKNVCLGLEDLQYVFMISSHELFITLLKDEERKLLVDQMRKRSPRVNLCIKPVTSFYDIPASASVNIGQLEHQLILSVDPWRIRQILIELHGMTSERQFWTVSNKWEVPSVYSSVILGIKDNLTRDLVYILMAKGLHCSTVKDFPHSKQLFTACLELVTEFSPKLRQVMLNEMLLLDIRTHEAGVGQSGERPPSDLISRVRGYLEMRLPDIPLRQVVAEECVAFMLNWRENEYLTLQVPAFLFQNNPYVKLGQLLAATCKELPGPKESRRTAKDLWEVVVQICSVSNQHKRGNDGRVSLIKQRESTLGIMYRSELLSFIKKLREPLVLTIILSLFVKLHNVREDIVNDITAEHISIWPSSIPNLQSVDFEAVAITVKELVRYTLSINPNNHAWLIIQADIYFATNQHSAALHYYLQAGAVCSDFFNKAVPPDVYTDQVIKRMIKCCSLLNCHTQVAILCQFLREIDYKTAFKSLQEQNSHDAMDSYYDYIWDVTILEYLTYLHHKRGETDKRQIAIKAIGQTELNASNPEEVLQLAAQRRKKKFLQAMAKLYF", "length": 995 }, "evidence": [ { "id": "HGNC:26048", "url": "https://alliancegenome.org/gene/HGNC:26048#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-556", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-556#orthology", "database": "AGR" }, { "id": "MGI:1919906", "url": "https://alliancegenome.org/gene/MGI:1919906#orthology", "database": "AGR" }, { "id": "RGD:1310592", "url": "https://alliancegenome.org/gene/RGD:1310592#orthology", "database": "AGR" }, { "id": "FB:FBgn0289323", "url": "https://alliancegenome.org/gene/FB:FBgn0289323#orthology", "database": "AGR" }, { "id": "A3KQN9", "url": "https://omabrowser.org/oma/group/A3KQN9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "chromosome", "id": "GO:0005694", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005694", "evidence": [ { "database": "UniProtKB", "id": "A3KQN9", "url": "https://www.uniprot.org/uniprotkb/A3KQN9" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "A3KQN9", "url": "https://www.uniprot.org/uniprotkb/A3KQN9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "snRNA 3'-end processing", "id": "GO:0034472", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034472", "evidence": [ { "database": "UniProtKB", "id": "A3KQN9", "url": "https://www.uniprot.org/uniprotkb/A3KQN9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 349, "end_pos": 351, "annotation": "n_glycosylation_sequon" }, { "start_pos": 489, "end_pos": 491, "annotation": "n_glycosylation_sequon" }, { "start_pos": 508, "end_pos": 510, "annotation": "n_glycosylation_sequon" }, { "start_pos": 581, "end_pos": 583, "annotation": "n_glycosylation_sequon" }, { "start_pos": 78, "end_pos": 80, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 835, "annotation": "n_glycosylation_sequon" }, { "start_pos": 968, "end_pos": 970, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A3KQN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQN9" }, { "id": "PF26725", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26725" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 8 N-terminal TPR repeats", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 310, "start_aa": "Thr", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "A3KQN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQN9" }, { "id": "PF26722", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26722" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 8 TPR repeat", "eco_id": "ECO_0000259", "start_pos": 319, "end_pos": 485, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "A3KQN9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQN9" }, { "id": "PF25756", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25756" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 8 TPR repeats", "eco_id": "ECO_0000259", "start_pos": 506, "end_pos": 995, "start_aa": "Ser", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 319, "end_pos": 321 }, { "start_pos": 349, "end_pos": 351 }, { "start_pos": 489, "end_pos": 491 }, { "start_pos": 508, "end_pos": 510 }, { "start_pos": 581, "end_pos": 583 }, { "start_pos": 78, "end_pos": 80 }, { "start_pos": 833, "end_pos": 835 }, { "start_pos": 968, "end_pos": 970 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A3KQR6-1", "uniprot_ac": "A3KQR6", "uniprot_id": "A3KQR6_DANRE", "mass": { "chemical_mass": 15343.0, "monoisotopic_mass": 15343.0 }, "refseq": { "ac": "NP_001082844", "name": "uncharacterized protein LOC557168 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082844" }, "gene_names": [ { "name": "si:dkey-240e12.6", "type": "recommended", "evidence": [ { "id": "A3KQR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQR6" } ] }, { "name": "si:dkey-240e12.6", "type": "synonym", "evidence": [ { "id": "NP_001082844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082844" } ] }, { "name": "si:dkey-270e21.3", "type": "synonym", "evidence": [ { "id": "NP_001082844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082844" }, { "id": "A3KQR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQR6" } ] }, { "name": "zgc:174228", "type": "synonym", "evidence": [ { "id": "NP_001082844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082844" }, { "id": "A3KQR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQR6" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC557168 precursor", "type": "synonym", "evidence": [ { "id": "A3KQR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQR6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC557168 precursor", "type": "synonym", "evidence": [ { "id": "NP_001082844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082844" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH510345.1, EH483899.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898399, SAMEA898400 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Dec 1, 2025 this sequence version replaced NP_001082844.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001082844", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082844" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KQR6", "url": "https://www.uniprot.org/uniprotkb/A3KQR6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-240e12.6", "url": "https://www.uniprot.org/uniprotkb/A3KQR6", "locus": {} } ], "crossref": [ { "id": "ENSDARG00000110137", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000110137", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22827", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22827", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "557168", "url": "https://www.ncbi.nlm.nih.gov/gene/557168", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000922", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000922", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:557168", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557168", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CEESTGH", "url": "https://omabrowser.org/oma/group/CEESTGH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A3KQR6", "url": "https://www.orthodb.org/?gene=A3KQR6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46780", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46780", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001082844", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082844", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A3KQR6", "url": "https://www.uniprot.org/uniprotkb/A3KQR6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KQR6-1", "url": "https://www.uniprot.org/uniprotkb/A3KQR6-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MGFLSFCLTLILLNSSLLISANGGHDHDDYEHCRRSTNSVTACEGSVLRLSCPGHTKIKILAANYGRTDKKTCNINLSPRQVRNTNCRSSNSLPRVSARCDGRESCYVPATNGVFSDPCPRTYKYLTVKYCCRRRWS", "length": 137, "header": "tr|A3KQR6-1|A3KQR6_DANRE Isoform 1 of Uncharacterized protein LOC557168 precursor OS=Danio rerio OX=7955 GN=si:dkey-240e12.6 PE=4 SV=1 CANONICAL=A3KQR6-1" }, "isoforms": [ { "isoform_ac": "A3KQR6-1", "url": "https://www.uniprot.org/uniprotkb/A3KQR6/entry#A3KQR6-1", "sequence": { "sequence": "MGFLSFCLTLILLNSSLLISANGGHDHDDYEHCRRSTNSVTACEGSVLRLSCPGHTKIKILAANYGRTDKKTCNINLSPRQVRNTNCRSSNSLPRVSARCDGRESCYVPATNGVFSDPCPRTYKYLTVKYCCRRRWS", "length": 137, "header": "tr|A3KQR6-1|A3KQR6_DANRE Isoform 1 of Uncharacterized protein LOC557168 precursor OS=Danio rerio OX=7955 GN=si:dkey-240e12.6 PE=4 SV=1 CANONICAL=A3KQR6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The earliest transcribed zygotic genes are short, newly evolved, and different across species.", "journal": "Cell Rep.", "date": "2014", "authors": "Heyn Patricia, Kircher Martin, Dahl Andreas, Kelso Janet, Tomancak Pavel, Kalinka Alex T, Neugebauer Karla M", "evidence": [ { "database": "UniProtKB", "id": "A3KQR6", "url": "https://www.uniprot.org/uniprotkb/A3KQR6" } ], "reference": [ { "type": "PubMed", "id": "24440719", "url": "https://glygen.org/publication/PubMed/24440719" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A3KQR6", "url": "https://www.uniprot.org/uniprotkb/A3KQR6" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:557168", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557168", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A3KQR6", "url": "https://www.uniprot.org/uniprotkb/A3KQR6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 76, "end_pos": 78, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A3KQR6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQR6" }, { "id": "PS50228", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50228" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SUEL-type lectin", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 133, "start_aa": "Ala", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 76, "end_pos": 78 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A3KQS1-1", "uniprot_ac": "A3KQS1", "uniprot_id": "A3KQS1_DANRE", "mass": { "chemical_mass": 43183.0, "monoisotopic_mass": 43183.0 }, "refseq": { "ac": "NP_001119912", "name": "proline-rich protein PRCC", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119912" }, "gene_names": [ { "name": "prcc", "type": "recommended", "evidence": [ { "id": "A3KQS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQS1" } ] }, { "name": "prcc", "type": "synonym", "evidence": [ { "id": "NP_001119912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119912" } ] }, { "name": "si:ch211-210h11.8", "type": "synonym", "evidence": [ { "id": "NP_001119912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119912" }, { "id": "A3KQS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQS1" } ] } ], "protein_names": [ { "name": "Proline-rich protein PRCC", "type": "synonym", "evidence": [ { "id": "A3KQS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3KQS1/entry#names_and_taxonomy" } ] }, { "name": "papillary renal cell carcinoma (translocation-associated)", "type": "synonym", "evidence": [ { "id": "NP_001119912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119912" } ] }, { "name": "proline-rich protein PRCC", "type": "synonym", "evidence": [ { "id": "NP_001119912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119912" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQQ01022375.1, GDQH01015641.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000019.1. On Jun 19, 2009 this sequence version replaced XP_700950.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001119912", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119912" } ] } ], "disease": [ { "disease_id": "DOID:4465", "recommended_name": { "id": "DOID:4465", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4465", "name": "papillary renal cell carcinoma", "description": "A renal cell carcinoma that is characterized by the development of multiple, bilateral papillary renal tumors." }, "synonyms": [ { "id": "DOID:4465", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4465", "name": "Chromophil carcinoma of kidney", "description": "" }, { "id": "DOID:4465", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4465", "name": "papillary kidney carcinoma", "description": "" }, { "id": "DOID:4465", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4465", "name": "sporadic papillary renal cell carcinoma", "description": "" }, { "id": "MONDO:0003789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0003789", "name": "hereditary papillary renal cell carcinoma", "description": "A familial carcinoma inherited in an autosomal dominant trait. It is characterized by the development of multiple, bilateral papillary renal cell carcinomas. The carcinomas range from microscopic lesions to clinically symptomatic tumors. It is associated with activating mutations of the MET oncogene." }, { "id": "MONDO:0003789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0003789", "name": "familial renal papillary carcinoma", "description": "" }, { "id": "MONDO:0003789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0003789", "name": "hereditary kidney papillary carcinoma", "description": "" }, { "id": "MONDO:0003789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0003789", "name": "hereditary papillary carcinoma of kidney", "description": "" }, { "id": "MONDO:0003789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0003789", "name": "hereditary papillary carcinoma of the kidney", "description": "" }, { "id": "MONDO:0003789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0003789", "name": "hereditary papillary renal carcinoma", "description": "" }, { "id": "MONDO:0003789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0003789", "name": "hereditary papillary renal cell cancer", "description": "" }, { "id": "MONDO:0003789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0003789", "name": "hereditary papillary renal cell carcinoma", "description": "" }, { "id": "MONDO:0003789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0003789", "name": "renal cell carcinoma, papillary", "description": "" }, { "id": "MONDO:0003789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0003789", "name": "renal cell carcinoma, papillary, 1, familial and somatic", "description": "" }, { "id": "MIM:605074", "resource": "MIM", "url": "https://www.omim.org/entry/605074", "name": "Renal cell carcinoma papillary", "description": "Renal cell carcinoma papillary" } ], "unlinked_id_list": [], "evidence": [ { "id": "4465", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4465" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3KQS1", "url": "https://www.uniprot.org/uniprotkb/A3KQS1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "prcc", "url": "https://www.uniprot.org/uniprotkb/A3KQS1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070717-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070717-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000063252", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000063252", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "572173", "url": "https://www.ncbi.nlm.nih.gov/gene/572173", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:572173", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:572173", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TRQSYSK", "url": "https://omabrowser.org/oma/group/TRQSYSK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A3KQS1", "url": "https://www.orthodb.org/?gene=A3KQS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13621", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13621", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13621:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13621:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10253", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10253", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-72163", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-72163", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001119912", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119912", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A3KQS1", "url": "https://www.uniprot.org/uniprotkb/A3KQS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3KQS1-1", "url": "https://www.uniprot.org/uniprotkb/A3KQS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070717-1", "url": "https://zfin.org/ZDB-GENE-070717-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSLVAYDSSDDSDRDDSPVLPARAPGRSGGLFASLPAPKNAEVRPTADEPAAAPQPKRTIMDLPKPKKRTEPVKIIVPQIKPADSDSDDDEPVRKKSAPRGSGLSSLLPQPKNLAVKETQRPLVPHTLTKRPASDKPKSNTAKPQSLSGSSPSPSAIKAAAKSAAMQLAKQMAADEDGSDDELAPENYFSLPESSVQPVIPQNVDAQQFVPSLHPPPGVEDAPLDFGSSKPVGAIQDYKTSGDFQHQYQELPDNTQPEASAQEYYGEEYYQDPNPGADEEEESGSSSLFNDEAFRRLQGKQNRGREEIKFLEIKGDDQLSGNKQWMTKNMTAEAEPRKSFSKKRGDQPTGQQRRKHQITYLIHQAKERELELKNNWADNKLTRRQTQAKYGF", "length": 392, "header": "tr|A3KQS1-1|A3KQS1_DANRE Isoform 1 of Proline-rich protein PRCC OS=Danio rerio OX=7955 GN=prcc PE=1 SV=1 CANONICAL=A3KQS1-1" }, "isoforms": [ { "isoform_ac": "A3KQS1-1", "url": "https://www.uniprot.org/uniprotkb/A3KQS1/entry#A3KQS1-1", "sequence": { "sequence": "MSLVAYDSSDDSDRDDSPVLPARAPGRSGGLFASLPAPKNAEVRPTADEPAAAPQPKRTIMDLPKPKKRTEPVKIIVPQIKPADSDSDDDEPVRKKSAPRGSGLSSLLPQPKNLAVKETQRPLVPHTLTKRPASDKPKSNTAKPQSLSGSSPSPSAIKAAAKSAAMQLAKQMAADEDGSDDELAPENYFSLPESSVQPVIPQNVDAQQFVPSLHPPPGVEDAPLDFGSSKPVGAIQDYKTSGDFQHQYQELPDNTQPEASAQEYYGEEYYQDPNPGADEEEESGSSSLFNDEAFRRLQGKQNRGREEIKFLEIKGDDQLSGNKQWMTKNMTAEAEPRKSFSKKRGDQPTGQQRRKHQITYLIHQAKERELELKNNWADNKLTRRQTQAKYGF", "length": 392, "header": "tr|A3KQS1-1|A3KQS1_DANRE Isoform 1 of Proline-rich protein PRCC OS=Danio rerio OX=7955 GN=prcc PE=1 SV=1 CANONICAL=A3KQS1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A3KQS1", "url": "https://www.uniprot.org/uniprotkb/A3KQS1" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:572173", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:572173", "resource": "KEGG Pathway" }, { "id": "R-DRE-72163", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-72163", "resource": "Reactome", "description": "mRNA Splicing - Major Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B2RYA6-1", "protein_name": "Proline rich mitotic checkpoint control factor", "gene_name": "Prcc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSLVAYASSDDSEPDEPEPEPEEEDVAAPMSGPTLGGLFASLPAPKGPALLHPPPQMLAPAFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPAGVSPAEAAGVGEGLGLPSPQGPGLSLPPAVGSVGPPLGLPKPKKRTEPVRIAAPELHKGDSDSEEDEPAKKKVVLQGSGEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDVSSDAKPSRLASKTKPASLAPVLGTTTTTPSPSAIKAAAKSAALQVTKQITQEDDDSDEEVAPENFFSLPDKAEPPGVEPYPYPVPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDANAAGAYYQDYYSGGYYPAPDPALVPSQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWSENKLSRRQTQAKYGF", "length": 489 }, "evidence": [ { "id": "HGNC:9343", "url": "https://alliancegenome.org/gene/HGNC:9343#orthology", "database": "AGR" }, { "id": "A3KQS1", "url": "https://omabrowser.org/oma/group/A3KQS1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q92733-1", "protein_name": "Proline-rich protein PRCC", "gene_name": "PRCC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLVAYASSDESEPDEAEPEPEEEEAVAPTSGPALGGLFASLPAPKGPALLPPPPQMLAPAFPPPLLLPPPTGDPRLQPPPPLPFGLGGFPPPPGVSPAEAAGVGEGLGLGLPSPRGPGLNLPPPIGGAGPPLGLPKPKKRKEPVKIAAPELHKGDSDSEEDEPTKKKTILQGSSEGTGLSALLPQPKNLTVKETNRLLLPHAFSRKPSDGSPDTKPSRLASKTKTSSLAPVVGTTTTTPSPSAIKAAAKSAALQVTKQITQEEDDSDEEVAPENFFSLPEKAEPPGVEPYPYPIPTVPEELPPGTEPEPAFQDDAANAPLEFKMAAGSSGAPWMPKPGDDYSYNQFSTYGDANAAGAYYQDYYSGGYYPAQDPALVPPQEIAPDASFIDDEAFKRLQGKRNRGREEINFVEIKGDDQLSGAQQWMTKSLTEEKTMKSFSKKKGEQPTGQQRRKHQITYLIHQAKERELELKNTWSENKLSRRQTQAKYGF", "length": 491 }, "evidence": [ { "id": "HGNC:9343", "url": "https://alliancegenome.org/gene/HGNC:9343#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070717-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070717-1#orthology", "database": "AGR" }, { "id": "A3KQS1", "url": "https://omabrowser.org/oma/group/A3KQS1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W0B6-1", "protein_name": "Proline-rich protein PRCC", "gene_name": "Dmel\\CG17249", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSLVAYAASSDEDSENEEENSVPQVEVIKPQAKPSTPSEAYLARESTSGHISDEDDDYVPQEVSLQELKPPNGRLLLALPKPKVTAPAKDLENEDVDNQVTSAFANLPMPRTAAKGKAIVEEKDDEFLHKKALPVEIEKPPPPPVKGKVKISIPSLRDFSDVDQEKADRAKNKVDKPNVPKGSGLLSLLPQAKSERNFSKNSSSAVAYPSASTTLASSLSNNPAQPRAAPAFVPDTVKQRRAAHNTEGVDGPKAGHKKNPETKDALKSTKSKPISKPTSLVNASDSEDDDEDGTGDFFSLNSEQKLPEVSSNEISALVAKRAAKMVEASSKYLEEVAEKEAAEAEAARLQEEQSQIAQKRYHEQQLNAEAMDALVGKNAKRRRKEAKEMQVIDISGSQVLPDREEWMRSALASSTTFQPTGVLTDEEPVAGTRRKHQITYLAHKAKANEAELQAMWSANRQTRRATQSKYGF", "length": 472 }, "evidence": [ { "id": "HGNC:9343", "url": "https://alliancegenome.org/gene/HGNC:9343#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A3KQS1", "url": "https://www.uniprot.org/uniprotkb/A3KQS1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 329, "end_pos": 331 } ] }, 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"publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A3QJU1-1", "uniprot_ac": "A3QJU1", "uniprot_id": "A3QJU1_DANRE", "mass": { "chemical_mass": 42568.0, "monoisotopic_mass": 42568.0 }, "refseq": { "ac": "NP_001093550", "name": "uncharacterized protein LOC100002638 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093550" }, "gene_names": [ { "name": "si:ch211-225k7.5", "type": "recommended", "evidence": [ { "id": "A3QJU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3QJU1" } ] }, { "name": "si:ch211-225k7.5", "type": "synonym", "evidence": [ { "id": "NP_001093550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093550" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100002638 precursor", "type": "synonym", "evidence": [ { "id": "A3QJU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3QJU1/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100002638 precursor", "type": "synonym", "evidence": [ { "id": "NP_001093550", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093550" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588719.3658486.1, SRR32588729.33260541.1 [ECO:0000332] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000007.1. On Jul 26, 2007 this sequence version replaced XP_001342382.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001093550", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093550" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A3QJU1", "url": "https://www.uniprot.org/uniprotkb/A3QJU1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-225k7.5", "url": "https://www.uniprot.org/uniprotkb/A3QJU1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-123", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-123", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03602", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03602", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100002638", "url": "https://www.ncbi.nlm.nih.gov/gene/100002638", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100002638", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100002638", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CAVIESK", "url": "https://omabrowser.org/oma/group/CAVIESK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A3QJU1", "url": "https://www.orthodb.org/?gene=A3QJU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001093550", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093550", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A3QJU1", "url": "https://www.uniprot.org/uniprotkb/A3QJU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A3QJU1-1", "url": "https://www.uniprot.org/uniprotkb/A3QJU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-123", "url": "https://zfin.org/ZDB-GENE-060503-123", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTQTQYFLLLIALCSISECVQRQYHFINEKKTWTEAQRYCREKYTDLATVDNMNDTIRLRKSVNDERIWIGLQKTSVYKWHWSSGDPALYLNLSSSPANNNNCTSKMRNGQWSVVPCNNNNYFICYNMSRGFVFVNQTMNWTAAQSYCRQNHTDLVTVRNQNENQQLEKFINDRNFSRSSVWIGLFRDTWQWSDQSNSSFRYWDTGKPNNSGGNESCTVIGQNSQRGWEEVSCDRQYPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLATTEAVWLGLRFSHISGIWFWVSGETVCYQNWAPGNGTSEEDCEPTVRSGAVQSEGDQTWISRPETDRLNFICSRYE", "length": 364, "header": "tr|A3QJU1-1|A3QJU1_DANRE Isoform 1 of Uncharacterized protein LOC100002638 precursor OS=Danio rerio OX=7955 GN=si:ch211-225k7.5 PE=4 SV=1 CANONICAL=A3QJU1-1" }, "isoforms": [ { "isoform_ac": "A3QJU1-1", "url": "https://www.uniprot.org/uniprotkb/A3QJU1/entry#A3QJU1-1", "sequence": { "sequence": "MTQTQYFLLLIALCSISECVQRQYHFINEKKTWTEAQRYCREKYTDLATVDNMNDTIRLRKSVNDERIWIGLQKTSVYKWHWSSGDPALYLNLSSSPANNNNCTSKMRNGQWSVVPCNNNNYFICYNMSRGFVFVNQTMNWTAAQSYCRQNHTDLVTVRNQNENQQLEKFINDRNFSRSSVWIGLFRDTWQWSDQSNSSFRYWDTGKPNNSGGNESCTVIGQNSQRGWEEVSCDRQYPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLATTEAVWLGLRFSHISGIWFWVSGETVCYQNWAPGNGTSEEDCEPTVRSGAVQSEGDQTWISRPETDRLNFICSRYE", "length": 364, "header": "tr|A3QJU1-1|A3QJU1_DANRE Isoform 1 of Uncharacterized protein LOC100002638 precursor OS=Danio rerio OX=7955 GN=si:ch211-225k7.5 PE=4 SV=1 CANONICAL=A3QJU1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "A3QJU1", "url": "https://www.uniprot.org/uniprotkb/A3QJU1" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] } ], "pathway": [ { "id": "dre:100002638", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100002638", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" }, { "start_pos": 214, "end_pos": 216, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A3QJU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3QJU1" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 24, "end_pos": 126, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 127, "end_pos": 129 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 140, "end_pos": 142 }, { "start_pos": 151, "end_pos": 153 }, { "start_pos": 175, "end_pos": 177 }, { "start_pos": 197, "end_pos": 199 }, { "start_pos": 209, "end_pos": 211 }, { "start_pos": 214, "end_pos": 216 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 54, "end_pos": 56 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": 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"title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A3QJY7-1", "uniprot_ac": "A3QJY7", "uniprot_id": "A3QJY7_DANRE", "mass": { "chemical_mass": 20670.0, "monoisotopic_mass": 20670.0 }, "refseq": { "ac": "NP_001121769", "name": "uncharacterized protein LOC100006693 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121769" }, "gene_names": [ { "name": "si:dkey-122c11.1", "type": "recommended", "evidence": [ { "id": "A3QJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3QJY7" } ] }, { "name": "si:dkey-122c11.1", "type": "synonym", "evidence": [ { "id": "NP_001121769", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121769" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100006693", "type": "synonym", "evidence": [ { "id": "A3QJY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A3QJY7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein 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The reference sequence was derived from JBMGRA010000004.1. 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"evidence": [ { "id": "NP_001092241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092241" }, { "id": "A5PLA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PLA0" } ] } ], "protein_names": [ { "name": "Reprimo-like protein", "type": "recommended", "evidence": [ { "id": "A5PLA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PLA0/entry#names_and_taxonomy" } ] }, { "name": "reprimo-like protein", "type": "synonym", "evidence": [ { "id": "NP_001092241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092241" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC142802.1 [ECO:0000332] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC142802.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001092241", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092241" } ] }, { "annotation": "The Reprimo gene family member, reprimo-like (rprml), is required for blood development in embryonic zebrafish. Erratum:[Sci Rep. 2020 Feb 28;10(1):4068. doi: 10.1038/s41598-020-59857-9. PMID: 32111873] Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001092241", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092241" }, { "database": "PubMed", "id": "31073223", "url": "https://glygen.org/publication/PubMed/31073223" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PLA0", "url": "https://www.uniprot.org/uniprotkb/A5PLA0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rprml", "url": "https://www.uniprot.org/uniprotkb/A5PLA0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070615-20", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070615-20", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A5PLA0", "url": "https://alphafold.ebi.ac.uk/entry/A5PLA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "100073335", "url": "https://www.ncbi.nlm.nih.gov/gene/100073335", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR043383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100073335", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100073335", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A5PLA0", "url": "https://www.orthodb.org/?gene=A5PLA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28649", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28649", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28649:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28649:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A5PLA0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A5PLA0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001092241", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092241", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5PLA0", "url": "https://www.uniprot.org/uniprotkb/A5PLA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PLA0-1", "url": "https://www.uniprot.org/uniprotkb/A5PLA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070615-20", "url": "https://zfin.org/ZDB-GENE-070615-20", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNGTFFNHTVFTHGVLLNRSQELAGTLVDCCTGNGSEVTANDGGGSLVLAQDERKLFVTRVVQIAVLCVLSLTVMFGIFFLGCNLMIKSESMINFLVKDRRSSKDVEAVMIGLS", "length": 114, "header": "sp|A5PLA0-1|RPRML_DANRE Isoform 1 of Reprimo-like protein OS=Danio rerio OX=7955 GN=rprml PE=3 SV=1 CANONICAL=A5PLA0-1" }, "isoforms": [ { "isoform_ac": "A5PLA0-1", "url": "https://www.uniprot.org/uniprotkb/A5PLA0/entry#A5PLA0-1", "sequence": { "sequence": "MNGTFFNHTVFTHGVLLNRSQELAGTLVDCCTGNGSEVTANDGGGSLVLAQDERKLFVTRVVQIAVLCVLSLTVMFGIFFLGCNLMIKSESMINFLVKDRRSSKDVEAVMIGLS", "length": 114, "header": "sp|A5PLA0-1|RPRML_DANRE Isoform 1 of Reprimo-like protein OS=Danio rerio OX=7955 GN=rprml PE=3 SV=1 CANONICAL=A5PLA0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The Reprimo gene family member, reprimo-like (rprml), is required for blood development in embryonic zebrafish.", "journal": "Scientific reports", "date": "2019-05-09", "authors": "Stanic Karen, Reig German, Figueroa Ricardo J, Retamal Pedro A, Wichmann Ignacio A, Opazo Juan C, Owen Gareth I, Corval\u00e1n Alejandro H, Concha Miguel L, Amigo Julio D", "evidence": [ { "database": "RefSeq", "id": "NP_001092241", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092241" } ], "reference": [ { "type": "PubMed", "id": "31073223", "url": "https://glygen.org/publication/PubMed/31073223" } ] } ], "pathway": [ { "id": "dre:100073335", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100073335", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z960-1", "protein_name": "Reprimo-like", "gene_name": "Rprml", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNVSFLNHSGLEEVGGDARATLGNRSHGLGTWLDCCPGGAPLTASDGVPAGLAPDERSLWVSRVAQIAVLCVLSLTVVFGVFFLGCNLLIKSESMINFLMQERRPSKDVGAAILGLY", "length": 117 }, "evidence": [ { "id": "RGD:1589060", "url": "https://alliancegenome.org/gene/RGD:1589060#orthology", "database": "AGR" }, { "id": "MGI:2144486", "url": "https://alliancegenome.org/gene/MGI:2144486#orthology", "database": "AGR" }, { "id": "HGNC:32422", "url": 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"sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 2, "end_pos": 4 }, { "start_pos": 34, "end_pos": 36 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5PLI4-1", "uniprot_ac": "A5PLI4", "uniprot_id": "LR2BP_DANRE", "mass": { "chemical_mass": 38144.0, "monoisotopic_mass": 38144.0 }, "refseq": { "ac": "NP_001092246", "name": "LRP2-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092246" }, "gene_names": [ { "name": "lrp2bp", "type": "recommended", "evidence": [ { "id": "A5PLI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PLI4" } ] }, { "name": "lrp2bp", "type": "synonym", "evidence": [ { "id": "NP_001092246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092246" } ] }, { "name": "zgc:165631", "type": "synonym", "evidence": [ { "id": "NP_001092246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092246" }, { "id": "A5PLI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PLI4" } ] } ], "protein_names": [ { "name": "LRP2-binding protein", "type": "recommended", "evidence": [ { "id": "A5PLI4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PLI4/entry#names_and_taxonomy" } ] }, { "name": "LRP2-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001092246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092246" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC142915.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN18715719 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC142915.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001092246", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092246" } ] }, { "annotation": "May act as an adapter that regulates LRP2 function.", "evidence": [ { "database": "UniProtKB", "id": "A5PLI4", "url": "https://www.uniprot.org/uniprotkb/A5PLI4#function" }, { "database": "UniProtKB", "id": "A0AC58H5B7", "url": "https://www.uniprot.org/uniprotkb/A0AC58H5B7#function" }, { "database": "UniProtKB", "id": "ARBA00037614", "url": "https://www.uniprot.org/uniprotkb/ARBA00037614#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PLI4", "url": "https://www.uniprot.org/uniprotkb/A5PLI4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "lrp2bp", "url": "https://www.uniprot.org/uniprotkb/A5PLI4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070615-41", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070615-41", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A5PLI4", "url": "https://alphafold.ebi.ac.uk/entry/A5PLI4", "database": "AlphaFoldDB", "categories": [] }, { "id": "100073340", "url": "https://www.ncbi.nlm.nih.gov/gene/100073340", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052323", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052323", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100073340", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100073340", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A5PLI4", "url": "https://www.orthodb.org/?gene=A5PLI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44554", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44554", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44554:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44554:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08238", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08238", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A5PLI4", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A5PLI4", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001092246", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092246", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58H5B7", "url": "https://www.uniprot.org/uniprotkb/A0AC58H5B7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H5B7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H5B7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PLI4", "url": "https://www.uniprot.org/uniprotkb/A5PLI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PLI4-1", "url": "https://www.uniprot.org/uniprotkb/A5PLI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070615-41", "url": "https://zfin.org/ZDB-GENE-070615-41", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDCSELDSTEKSKPSQLLRAINQIYEEGREESTHSETNAASVEKTMNLLKEKAETGDSQATFLLGQLHYVQGCYAEAELIFDRIKDKDPQALYQLAVIYYDGLGTKEDLGRAVEYMGRVAFWDSSEAGSVRYAALYNLGQAYLEGFGVQASSSEAERLWLLAADNGNPNASVKAQSALGMFYSRPESLDLRKAFFWHSQACGNGSLESQAALGLMYLYGHGVQRDSDSALFCLKEAAERGSVYAQGHLTACYYRRQLYSRAAALGQRVCEYKDTAAIAQQTDCLEEYVRKGIAIGMFYYARCLHLGRGVPQNRDKAKHYCTQAVRIDPLICKELQIDAAHGKI", "length": 343, "header": "sp|A5PLI4-1|LR2BP_DANRE Isoform 1 of LRP2-binding protein OS=Danio rerio OX=7955 GN=lrp2bp PE=2 SV=1 CANONICAL=A5PLI4-1" }, "isoforms": [ { "isoform_ac": "A0AC58H5B7-1", "url": "https://www.uniprot.org/uniprotkb/A5PLI4/entry#A0AC58H5B7-1", "sequence": { "sequence": "MDCSELDSTEKSKPSQLLRAINQIYEEGREESTHSAETNAASVEKTMNLLKEKAETGDSQATFLLGQLHYVQGCYTEAELIFNRIKDKDPQALYQLAVIYYDGLGTKEDLGRAVEYMGRVAFWDSSEAGSVRYAALYNLGQAYLEGFGVQASSSEAERLWLLAADDGNPNASVKAQSALGMFYSRPESLDLRKAFFWHSQACGNGSLESQAALGLMYLYGHGVQRDSDSALFCLKEAAERGSVYAQGHLTACYYRRQLYSRAAALGQRVCEYKDTAAIAQQTDCLEEYVRKGIAIGMFYYARCLHLGRGVPQNRDKAKHYCTQAVRIDPLICKELQIDAAHGKI", "length": 344, "header": "tr|A0AC58H5B7-1|A0AC58H5B7_DANRE Computationally mapped isoform of LRP2-binding protein OS=Danio rerio OX=7955 GN=lrp2bp PE=4 SV=1 CANONICAL=A5PLI4-1" }, "locus": {} }, { "isoform_ac": "A5PLI4-1", "url": "https://www.uniprot.org/uniprotkb/A5PLI4/entry#A5PLI4-1", "sequence": { "sequence": "MDCSELDSTEKSKPSQLLRAINQIYEEGREESTHSETNAASVEKTMNLLKEKAETGDSQATFLLGQLHYVQGCYAEAELIFDRIKDKDPQALYQLAVIYYDGLGTKEDLGRAVEYMGRVAFWDSSEAGSVRYAALYNLGQAYLEGFGVQASSSEAERLWLLAADNGNPNASVKAQSALGMFYSRPESLDLRKAFFWHSQACGNGSLESQAALGLMYLYGHGVQRDSDSALFCLKEAAERGSVYAQGHLTACYYRRQLYSRAAALGQRVCEYKDTAAIAQQTDCLEEYVRKGIAIGMFYYARCLHLGRGVPQNRDKAKHYCTQAVRIDPLICKELQIDAAHGKI", "length": 343, "header": "sp|A5PLI4-1|LR2BP_DANRE Isoform 1 of LRP2-binding protein OS=Danio rerio OX=7955 GN=lrp2bp PE=2 SV=1 CANONICAL=A5PLI4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100073340", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100073340", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q569C2-1", "protein_name": "LRP2-binding protein", "gene_name": "Lrp2bp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKLTSEKLPKNPFSLSQYAAKQQTFFQWKKEKPDYYRHANLVDTALQFLKERIRKGDAMAYFLRGQLYFEEGWYEEALAQFEEIQEKDHQAIYQLGVMYYDGLGTVADAEKGVGYMKKILDSSCPQTMHLKFAAAYNLGRAYFEGKGVKRSDEEAERLWLYAADNGNPKASVKAQSILGLFYSMKEPKDLEKAFFWHSEACGNGNLESQGALGLMYLYGQGIRQDTDAALHCLREAAERGNVYAQGILVEYYYKMKFFTKCVSFSKRIADYDEVHDIPMIAHVTDCLPEFISKGMAMASFYYARCLQLGLGITKDEASAKHYYSKACRLNPTLADELHSLLIHQRI", "length": 346 }, "evidence": [ { "id": "RGD:1305896", "url": "https://alliancegenome.org/gene/RGD:1305896#orthology", "database": "AGR" }, { "id": "MGI:1914870", "url": "https://alliancegenome.org/gene/MGI:1914870#orthology", "database": "AGR" }, { "id": "HGNC:25434", "url": "https://alliancegenome.org/gene/HGNC:25434#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070615-41", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070615-41#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9D4C6-1", "protein_name": "LRP2-binding protein", "gene_name": "Lrp2bp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKLSSEKLPKNPFSLSQYAAKQQKFFQWKKEKPDYYLHANLVDTALQFLKERIRRGDAMAYFLRGQLYFEEGWYEEALAQFEEIQEKDHQAIYQLGVMYYDGLGTIANAEKGVNYMRKILDSSCPQTMHLKFAAAYNLGRAYFEGKGVKRSDEEAERLWLLAADNGNPKASVKAQSILGLFYSMKEPKELEKAFFWHSEACGNGSLESQGALGLMYFYGQGIRQDTDAALHCLREAAERGNVYAQGTLVEYYYKMKFFTKCVSFSKRIADYDEVHDIPMIAHVTDCLPEFIIKGMAMAAFYHGRCLQLGLGIMKDEESAKHYYSKACRLNPTLADELHSLLIHQRI", "length": 346 }, "evidence": [ { "id": "RGD:1305896", "url": "https://alliancegenome.org/gene/RGD:1305896#orthology", "database": "AGR" }, { "id": "MGI:1914870", "url": "https://alliancegenome.org/gene/MGI:1914870#orthology", "database": "AGR" }, { "id": "HGNC:25434", "url": "https://alliancegenome.org/gene/HGNC:25434#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070615-41", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070615-41#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2M1-1", "protein_name": "LRP2-binding protein", "gene_name": "LRP2BP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKLTSEKLPKNPFYASVSQYAAKNQKFFQWKKEKTDYTHANLVDKALQLLKERILKGDTLAYFLRGQLYFEEGWYEEALEQFEEIKEKDHQATYQLGVMYYDGLGTTLDAEKGVDYMKKILDSPCPKARHLKFAAAYNLGRAYYEGKGVKRSNEEAERLWLIAADNGNPKASVKAQSMLGLYYSTKEPKELEKAFYWHSEACGNGNLESQGALGLMYLYGQGIRQDTEAALQCLREAAERGNVYAQGNLVEYYYKMKFFTKCVAFSKRIADYDEVHDIPMIAQVTDCLPEFIGRGMAMASFYHARCLQLGLGITRDETTAKHYYSKACRLNPALADELHSLLIRQRI", "length": 347 }, "evidence": [ { "id": "RGD:1305896", "url": "https://alliancegenome.org/gene/RGD:1305896#orthology", "database": "AGR" }, { "id": "MGI:1914870", "url": "https://alliancegenome.org/gene/MGI:1914870#orthology", "database": "AGR" }, { "id": "HGNC:25434", "url": "https://alliancegenome.org/gene/HGNC:25434#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070615-41", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070615-41#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5PLI4", "url": "https://www.uniprot.org/uniprotkb/A5PLI4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 203, "end_pos": 205, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 169, "end_pos": 171 }, { "start_pos": 203, "end_pos": 205 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A5PM71-1", "uniprot_ac": "A5PM71", "uniprot_id": "A5PM71_DANRE", "mass": { "chemical_mass": 25481.0, "monoisotopic_mass": 25481.0 }, "refseq": { "ac": "NP_001121846", "name": "uncharacterized protein LOC100148058", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121846" }, "gene_names": [ { "name": "si:dkeyp-72a4.1", "type": "recommended", "evidence": [ { "id": "A5PM71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PM71" } ] }, { "name": "si:dkeyp-72a4.1", "type": "synonym", "evidence": [ { "id": "NP_001121846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121846" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100148058", "type": "synonym", "evidence": [ { "id": "A5PM71", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PM71/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100148058", "type": "synonym", "evidence": [ { "id": "NP_001121846", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121846" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH553636.1, SRR32588720.2707004.1 [ECO:0000332] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000005.1. On Jul 31, 2008 this sequence version replaced XP_001922559.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001121846", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121846" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PM71", "url": "https://www.uniprot.org/uniprotkb/A5PM71" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkeyp-72a4.1", "url": "https://www.uniprot.org/uniprotkb/A5PM71", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-551", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-551", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000093985", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000093985", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100148058", "url": "https://www.ncbi.nlm.nih.gov/gene/100148058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100148058", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148058", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A5PM71", "url": "https://www.orthodb.org/?gene=A5PM71", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001121846", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121846", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5PM71", "url": "https://www.uniprot.org/uniprotkb/A5PM71", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PM71-1", "url": "https://www.uniprot.org/uniprotkb/A5PM71-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-551", "url": "https://zfin.org/ZDB-GENE-070705-551", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MQRRRNTMENPLFCSSPNQHHGWIQVSDMRSPPGHWMSCGHSCAEHAVWNPKFCVVTDYQMLLLDKEEIHPLLLQEKRTDSSKSRLLRRTISVPVETHFPGFQSHLSVDNNERASGAGEGRREDEGFLQFFTVINKRIFQSFSLSHFWPMGTACMSALTEGDSLIIRPKTKDCVFACSHLTECLVARISLYYLSSFRVFACKKLSRLVSRVTLSLQKPMRTV", "length": 222, "header": "tr|A5PM71-1|A5PM71_DANRE Isoform 1 of Uncharacterized protein LOC100148058 OS=Danio rerio OX=7955 GN=si:dkeyp-72a4.1 PE=4 SV=1 CANONICAL=A5PM71-1" }, "isoforms": [ { "isoform_ac": "A5PM71-1", "url": "https://www.uniprot.org/uniprotkb/A5PM71/entry#A5PM71-1", "sequence": { "sequence": "MQRRRNTMENPLFCSSPNQHHGWIQVSDMRSPPGHWMSCGHSCAEHAVWNPKFCVVTDYQMLLLDKEEIHPLLLQEKRTDSSKSRLLRRTISVPVETHFPGFQSHLSVDNNERASGAGEGRREDEGFLQFFTVINKRIFQSFSLSHFWPMGTACMSALTEGDSLIIRPKTKDCVFACSHLTECLVARISLYYLSSFRVFACKKLSRLVSRVTLSLQKPMRTV", "length": 222, "header": "tr|A5PM71-1|A5PM71_DANRE Isoform 1 of Uncharacterized protein LOC100148058 OS=Danio rerio OX=7955 GN=si:dkeyp-72a4.1 PE=4 SV=1 CANONICAL=A5PM71-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A5PM71", "url": "https://www.uniprot.org/uniprotkb/A5PM71" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100148058", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148058", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5PM73-1", "uniprot_ac": "A5PM73", "uniprot_id": "A5PM73_DANRE", "mass": { "chemical_mass": 66877.0, "monoisotopic_mass": 66877.0 }, "refseq": { "ac": "NP_001121868", "name": "uncharacterized protein LOC100149646 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121868" }, "gene_names": [ { "name": "si:ch211-165i18.2", "type": "recommended", "evidence": [ { "id": "A5PM73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PM73" } ] }, { "name": "si:ch211-165i18.2", "type": "synonym", "evidence": [ { "id": "NP_001121868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121868" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100149646 precursor", "type": "synonym", "evidence": [ { "id": "A5PM73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PM73/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100149646 precursor", "type": "synonym", "evidence": [ { "id": "NP_001121868", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121868" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA708836, SAMEA898401 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from BX005475.20. On Jul 31, 2008 this sequence version replaced XP_001919645.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001121868", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121868" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PM73", "url": "https://www.uniprot.org/uniprotkb/A5PM73" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-165i18.2", "url": "https://www.uniprot.org/uniprotkb/A5PM73", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-77", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-77", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077239", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077239", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100149646", "url": "https://www.ncbi.nlm.nih.gov/gene/100149646", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020821", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020821", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039015", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039015", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044925", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044925", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044929", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044929", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100149646", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100149646", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MILWASI", "url": "https://omabrowser.org/oma/group/MILWASI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5PM73", "url": "https://www.orthodb.org/?gene=A5PM73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21472", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21472", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21472:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21472:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01223", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01223", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001121868", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121868", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5PM73", "url": "https://www.uniprot.org/uniprotkb/A5PM73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PM73-1", "url": "https://www.uniprot.org/uniprotkb/A5PM73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-77", "url": "https://zfin.org/ZDB-GENE-070705-77", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFALGLLICVVLRALSARAKVVTSFNECSEFFYQGTEPAGMDQNAKRICQKVEYGGFYYATLYSVPQRMPLYSAYTLDRDCTTTTGRADVWHVETQISQPGSRTDHMVRERDSNINTIKAKQAISDDYTDTGYDRGHLNPNSFQCDEGRKATFTLTNAAPMDACFNRIHWKSWESTTRSLLLGKLITDGSSAEAYIVTGTVPSADIRIPQKEVSTDPERVTVPSHIWTAVCYKHQTDPEQSFSFSYLGKNLPEGGISLMSVSNLNIQLSQLYGQLSGTSPLISVFADDCFEDNNKLNKVQTAFQKLINLAANQVVQMSSSSQNTYNALQNAVSDYSIPSKKFKVSQMTVKLAFDSLSTYFTVAEVLKTLYTSSCLITRAKPLVRRLGKRDLSDESSDAVECLLVPEKQITAADGSSCLTIYKTHYWCNCSPKPGDAAKSCCTSPCLYKAKLRDYRCYNGQYLISCSPQYSLITVNGETCKDEHPCATYGYDYYWCRTTSDKWDYCSPPLWNSKAENGKYCRTNHACAKYGESKPWCYTDNEGTRGHCCTSDDCYSAVNGKTCRPNHKCSNYGKKYLWCYIDDDNNWEYCCTKCSY", "length": 595, "header": "tr|A5PM73-1|A5PM73_DANRE Isoform 1 of Uncharacterized protein LOC100149646 precursor OS=Danio rerio OX=7955 GN=si:ch211-165i18.2 PE=4 SV=1 CANONICAL=A5PM73-1" }, "isoforms": [ { "isoform_ac": "A5PM73-1", "url": "https://www.uniprot.org/uniprotkb/A5PM73/entry#A5PM73-1", "sequence": { "sequence": "MFALGLLICVVLRALSARAKVVTSFNECSEFFYQGTEPAGMDQNAKRICQKVEYGGFYYATLYSVPQRMPLYSAYTLDRDCTTTTGRADVWHVETQISQPGSRTDHMVRERDSNINTIKAKQAISDDYTDTGYDRGHLNPNSFQCDEGRKATFTLTNAAPMDACFNRIHWKSWESTTRSLLLGKLITDGSSAEAYIVTGTVPSADIRIPQKEVSTDPERVTVPSHIWTAVCYKHQTDPEQSFSFSYLGKNLPEGGISLMSVSNLNIQLSQLYGQLSGTSPLISVFADDCFEDNNKLNKVQTAFQKLINLAANQVVQMSSSSQNTYNALQNAVSDYSIPSKKFKVSQMTVKLAFDSLSTYFTVAEVLKTLYTSSCLITRAKPLVRRLGKRDLSDESSDAVECLLVPEKQITAADGSSCLTIYKTHYWCNCSPKPGDAAKSCCTSPCLYKAKLRDYRCYNGQYLISCSPQYSLITVNGETCKDEHPCATYGYDYYWCRTTSDKWDYCSPPLWNSKAENGKYCRTNHACAKYGESKPWCYTDNEGTRGHCCTSDDCYSAVNGKTCRPNHKCSNYGKKYLWCYIDDDNNWEYCCTKCSY", "length": 595, "header": "tr|A5PM73-1|A5PM73_DANRE Isoform 1 of Uncharacterized protein LOC100149646 precursor OS=Danio rerio OX=7955 GN=si:ch211-165i18.2 PE=4 SV=1 CANONICAL=A5PM73-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100149646", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100149646", "resource": "KEGG Pathway" }, { "id": "R-DRE-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZIP8-1", "protein_name": "Endonuclease domain containing 1", "gene_name": "Endod1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCARWLALGGLLALLGLLQARLLLPQQAGFGECDRFFYAGTPPAGLATEAHVRICQRFAGSERFATLYSPGHRIPVFSAFRAARPASRSAEQRGLLEPQIDDPDSNLEEVIDEADAVSVNNLGSKQALSADYLDSDYEIGQLYPFPLNSDLQMSAFPLTNSVPMTRSFRERWHMNLNSLMDRALIPQCSDGKDLYLLTGAVPSDHKVKGKVTVPEFVWLAACCAVPGGGWAMGFIKHTQDSDVIEDVMVRDLEKLLLHKPQLFQDNCGETEQDTEKMKKILEVVNQVQDEERSLQSQENMSPLASTRSQRSALLSPEAPPEGGGSFLGKVLGFLTTPFIKLFQLIYYLITAVLRNVVHLLWFVAKQVINGVASSLYGLGEAVVSYLVAIGQELVSIPWKVLKVVAKVIRAFLRILCCVLKAVCRALSIPLRVLVDVATFPVYTMGAIPIVCKDIAVGLGGTLSLLFDTAFGTMGGLFQIVFSVFKRIGCRVTLDSSGEL", "length": 500 }, "evidence": [ { "id": "RGD:1310444", "url": "https://alliancegenome.org/gene/RGD:1310444#orthology", "database": "AGR" }, { "id": "HGNC:29129", "url": "https://alliancegenome.org/gene/HGNC:29129#orthology", "database": "AGR" }, { "id": "MGI:1919196", "url": "https://alliancegenome.org/gene/MGI:1919196#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-77", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-77#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O94919-1", "protein_name": "Endonuclease domain-containing 1 protein", "gene_name": "ENDOD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGTARWLALGSLFALAGLLEGRLVGEEEAGFGECDKFFYAGTPPAGLAADSHVKICQRAEGAERFATLYSTRDRIPVYSAFRAPRPAPGGAEQRWLVEPQIDDPNSNLEEAINEAEAITSVNSLGSKQALNTDYLDSDYQRGQLYPFSLSSDVQVATFTLTNSAPMTQSFQERWYVNLHSLMDRALTPQCGSGEDLYILTGTVPSDYRVKDKVAVPEFVWLAACCAVPGGGWAMGFVKHTRDSDIIEDVMVKDLQKLLPFNPQLFQNNCGETEQDTEKMKKILEVVNQIQDEERMVQSQKSSSPLSSTRSKRSTLLPPEASEGSSSFLGKLMGFIATPFIKLFQLIYYLVVAILKNIVYFLWCVTKQVINGIESCLYRLGSATISYFMAIGEELVSIPWKVLKVVAKVIRALLRILCCLLKAICRVLSIPVRVLVDVATFPVYTMGAIPIVCKDIALGLGGTVSLLFDTAFGTLGGLFQVVFSVCKRIGYKVTFDNSGEL", "length": 500 }, "evidence": [ { "id": "RGD:1310444", "url": "https://alliancegenome.org/gene/RGD:1310444#orthology", "database": "AGR" }, { "id": "HGNC:29129", "url": "https://alliancegenome.org/gene/HGNC:29129#orthology", "database": "AGR" }, { "id": "MGI:1919196", "url": "https://alliancegenome.org/gene/MGI:1919196#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-77", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-77#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C522-1", "protein_name": "Endonuclease domain-containing 1 protein", "gene_name": "Endod1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCARWLALGGLLALAGLLQARLLLPQQAGFGECDRFFYKGTPPAGLATEAHVRICQRFAGSERFATLYSPGHRIPVFSAFRAARPASRSAEQRGLLEPQIDDPDSNLEEVIDEANALTSVDNLGSKQALNADYIDSDYEIGQLYPFPLNSDLQMATFPLTNSVPMTQSFRERWHMNLNSLMDRALIPHCSEGKDLYILTGAVPSEHRVKGKVTIPEFVWLAACCAVPGEGWAMGFIKHTQDIDVIEDVMLRDLEKLLPHKPQLFQDNCGEMEQDTEKMKKILEVVNQVQDEERSLQSQERMSPLASTQSQRSALLSPEAPPEGGSSFLGQVLGFLATPFIKLFQLIYYLVTAVLRNIVHLLWLVAKQAINTVESCLYHLGEATVSYLVAIGQELVSIPWKVLKVVAKVIRAFLRILCCLLKAVCRALSIPLRVLVDVATFPVYTVGAIPIVCKDIAVGLGGTLSLLFDTAFGTVGGLFQIVFSVFKRIGYKVTLDNSGEF", "length": 501 }, "evidence": [ { "id": "RGD:1310444", "url": "https://alliancegenome.org/gene/RGD:1310444#orthology", "database": "AGR" }, { "id": "HGNC:29129", "url": "https://alliancegenome.org/gene/HGNC:29129#orthology", "database": "AGR" }, { "id": "MGI:1919196", "url": "https://alliancegenome.org/gene/MGI:1919196#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-77", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-77#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A5PM73", "url": "https://www.uniprot.org/uniprotkb/A5PM73" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "A5PM73", "url": "https://www.uniprot.org/uniprotkb/A5PM73" } ], "pmid": "" }, { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "A5PM73", "url": "https://www.uniprot.org/uniprotkb/A5PM73" } ], "pmid": "" }, { "name": "endonuclease activity", "id": "GO:0004519", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004519", "evidence": [ { "database": "UniProtKB", "id": "A5PM73", "url": "https://www.uniprot.org/uniprotkb/A5PM73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5PM73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PM73" }, { "id": "SM00892", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00892" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DNA/RNA non-specific endonuclease/pyrophosphatase/phosphodiesterase", "eco_id": "ECO_0000259", "start_pos": 55, "end_pos": 281, "start_aa": "Gly", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "A5PM73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PM73" }, { "id": "SM00477", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00477" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ENPP1-3/EXOG-like endonuclease/phosphodiesterase", "eco_id": "ECO_0000259", "start_pos": 56, "end_pos": 279, "start_aa": "Gly", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 428, "end_pos": 430 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A5PMB7-1", "uniprot_ac": "A5PMB7", "uniprot_id": "A5PMB7_DANRE", "mass": { "chemical_mass": 30494.0, "monoisotopic_mass": 30494.0 }, "refseq": { "ac": "XP_001337454", "name": "START domain-containing protein 10", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001337454" }, "gene_names": [ { "name": "stard15", "type": "recommended", "evidence": [ { "id": "A5PMB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMB7" } ] }, { "name": "stard15", "type": "synonym", "evidence": [ { "id": "XP_001337454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001337454" } ] } ], "protein_names": [ { "name": "START domain-containing protein 10", "type": "recommended", "evidence": [ { "id": "A5PMB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMB7/entry#names_and_taxonomy" } ] }, { "name": "PCTP-like protein", "type": "synonym", "evidence": [ { "id": "A5PMB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMB7/entry#names_and_taxonomy" } ] }, { "name": "START domain-containing protein 10", "type": "synonym", "evidence": [ { "id": "XP_001337454", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001337454" } ] }, { "name": "StAR-related lipid transfer protein 10", "type": "synonym", "evidence": [ { "id": "A5PMB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMB7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001337454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001337454" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMB7", "url": "https://www.uniprot.org/uniprotkb/A5PMB7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "stard15", "url": "https://www.uniprot.org/uniprotkb/A5PMB7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070424-267", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-267", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000071585", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000071585", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08871", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08871", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "797016", "url": "https://www.ncbi.nlm.nih.gov/gene/797016", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002913", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002913", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR023393", "url": "https://www.ebi.ac.uk/interpro/entry/IPR023393", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:797016", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797016", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PNYKPWH", "url": "https://omabrowser.org/oma/group/PNYKPWH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5PMB7", "url": "https://www.orthodb.org/?gene=A5PMB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19308:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19308:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01852", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01852", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001337454", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001337454", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5PMB7", "url": 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"MPVQIPDDTDFLSFRDQCESQDGWVSRYNKGSVTVWCRDEECKSVQKLKMRIVCKDVTAETLYDVLHDTSYRKKWDTNMIDTFDIGRLTVNADVGYYSWKCPTPLKNRDFVTMRSWLPLGNDYLIINYSVKHPEYPPKKDYVRAVSLLTGYLIQSNGANSCTLYYLTQVDPRGSLPKWVVNRVSQFVAPKAMKKIYKACLKYPEWKRKHEPNLKPWRYPEQNTLPCINVADLTVQRADSLENIDESGVSEEKAQHHSDDDET", "length": 262, "header": "tr|A5PMB7-1|A5PMB7_DANRE Isoform 1 of START domain-containing protein 10 OS=Danio rerio OX=7955 GN=stard15 PE=4 SV=1 CANONICAL=A5PMB7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:797016", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797016", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A5PMB7", "url": "https://www.uniprot.org/uniprotkb/A5PMB7" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A5PMB7", "url": "https://www.uniprot.org/uniprotkb/A5PMB7" } ], "pmid": "" }, { "name": "motile cilium", "id": "GO:0031514", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031514", "evidence": [ { "database": "UniProtKB", "id": "A5PMB7", "url": "https://www.uniprot.org/uniprotkb/A5PMB7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "lipid transport", "id": "GO:0006869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006869", "evidence": [ { "database": "UniProtKB", "id": "A5PMB7", "url": "https://www.uniprot.org/uniprotkb/A5PMB7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "lipid binding", "id": "GO:0008289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008289", "evidence": [ { "database": "UniProtKB", "id": "A5PMB7", "url": "https://www.uniprot.org/uniprotkb/A5PMB7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5PMB7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMB7" }, { "id": "PS50848", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50848" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "START", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 204, "start_aa": "Ser", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A5PMF8-1", "uniprot_ac": "A5PMF8", "uniprot_id": "A5PMF8_DANRE", "mass": { "chemical_mass": 15722.0, "monoisotopic_mass": 15722.0 }, "refseq": { "ac": "NP_001104231", "name": "uncharacterized protein LOC796649", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104231" }, "gene_names": [ { "name": "si:ch211-114l13.9", "type": "recommended", "evidence": [ { "id": "A5PMF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMF8" } ] }, { "name": "si:ch211-114l13.9", "type": "synonym", "evidence": [ { "id": "NP_001104231", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104231" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC796649", "type": "synonym", "evidence": [ { "id": "A5PMF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMF8/entry#names_and_taxonomy" } ] }, { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A5PMF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMF8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC796649", "type": "synonym", "evidence": [ { "id": "NP_001104231", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104231" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: DT069020.1, EV757681.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505378, SAMEA3505380 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000001.1. On Nov 18, 2007 this sequence version replaced XP_001332587.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001104231", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104231" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMF8", "url": "https://www.uniprot.org/uniprotkb/A5PMF8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-114l13.9", "url": "https://www.uniprot.org/uniprotkb/A5PMF8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070424-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-116", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092894", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092894", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08321", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08321", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "796649", "url": "https://www.ncbi.nlm.nih.gov/gene/796649", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:796649", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796649", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A5PMF8", "url": "https://www.orthodb.org/?gene=A5PMF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF02758", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02758", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001104231", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104231", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5PMF8", "url": "https://www.uniprot.org/uniprotkb/A5PMF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PMF8-1", "url": "https://www.uniprot.org/uniprotkb/A5PMF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070424-116", "url": "https://zfin.org/ZDB-GENE-070424-116", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASTKTEILDVLDELREREFKDFKWRLSNKETLENSIPRGKLENADRQDVVDYMEQHFGTSEAGKVAVRLLHSMNQNNLAEQLKKTLAVVSKVSDVDSGSSSSRGNPPTAPSPAAGVVMNLNASGGNIKAPVIHNSVINGSVNFG", "length": 145, "header": "tr|A5PMF8-1|A5PMF8_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-114l13.9 PE=4 SV=1 CANONICAL=A5PMF8-1" }, "isoforms": [ { "isoform_ac": "A5PMF8-1", "url": "https://www.uniprot.org/uniprotkb/A5PMF8/entry#A5PMF8-1", "sequence": { "sequence": "MASTKTEILDVLDELREREFKDFKWRLSNKETLENSIPRGKLENADRQDVVDYMEQHFGTSEAGKVAVRLLHSMNQNNLAEQLKKTLAVVSKVSDVDSGSSSSRGNPPTAPSPAAGVVMNLNASGGNIKAPVIHNSVINGSVNFG", "length": 145, "header": "tr|A5PMF8-1|A5PMF8_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-114l13.9 PE=4 SV=1 CANONICAL=A5PMF8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A5PMF8", "url": "https://www.uniprot.org/uniprotkb/A5PMF8" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A5PMF8", "url": "https://www.uniprot.org/uniprotkb/A5PMF8" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:796649", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796649", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 139, "end_pos": 141, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5PMF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMF8" }, { "id": "PS50824", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50824" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Pyrin", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 89, "start_aa": "Met", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 139, "end_pos": 141 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5PMH0-1", "uniprot_ac": "A5PMH0", "uniprot_id": "A5PMH0_DANRE", "mass": { "chemical_mass": 73221.0, "monoisotopic_mass": 73221.0 }, "refseq": { "ac": "NP_001002655", "name": "ataxin-7-like protein 2b", "summary": "", "url": 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"NP_001002655", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002655" }, { "id": "A5PMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMH0" } ] } ], "protein_names": [ { "name": "Ataxin-7-like protein 2b", "type": "synonym", "evidence": [ { "id": "A5PMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMH0/entry#names_and_taxonomy" } ] }, { "name": "ataxin 7-like 2", "type": "synonym", "evidence": [ { "id": "NP_001002655", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002655" } ] }, { "name": "ataxin-7-like protein 2b", "type": "synonym", "evidence": [ { "id": "NP_001002655", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002655" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC096979.1, GFIL01002056.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Sep 17, 2011 this sequence version replaced NP_001002655.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001002655", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002655" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMH0", "url": "https://www.uniprot.org/uniprotkb/A5PMH0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "atxn7l2b", "url": "https://www.uniprot.org/uniprotkb/A5PMH0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040718-403", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-403", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000056268", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000056268", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "436928", "url": "https://www.ncbi.nlm.nih.gov/gene/436928", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013243", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013243", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052237", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052237", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:436928", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:436928", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NSNCHIL", "url": "https://omabrowser.org/oma/group/NSNCHIL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5PMH0", "url": "https://www.orthodb.org/?gene=A5PMH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15117", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15117", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15117:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15117:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08313", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08313", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001002655", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002655", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5PMH0", "url": "https://www.uniprot.org/uniprotkb/A5PMH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PMH0-1", "url": "https://www.uniprot.org/uniprotkb/A5PMH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040718-403", "url": "https://zfin.org/ZDB-GENE-040718-403", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVADRARAKTVMAALDRRISILDYVGQSWAAWIDKANVSTPDGPPLEECSKNVKKRMETMTLKKEDMSIYGHCPAHDNFFLVVCSHCGQVVKPQAFEKHCERRHGPFSKLYGTPSNCSPDRPQQGRPPSSQHVSLCEGQDGRHQGAGPPRVPPPHPPHQGRPKPQREAPSLQPLDKVPHVKPPSPSDLPTPPKKALPSAEKPIIQKGLDSHGPRTYSRTFKKVLKKECDVNKHCGVMDPERKKVCTRLLTCNIHSIHQRRQVVGRRKPFDQLVMELKMSSKPRERPPLPREISDGGSVNHETPAPQTGPLHYKCQITNSSILRSVNPSEGVVEVKEEVMRSEETQAESLSAALSSEESDGENREEFAHLPASTLHPKPLGLCTFGARVLGRSVLAFDRRLLHLRSAFSVMMEQHLSTYLWKKLPQVSELCSNQQQITYNSHDATRSSAPIHITSTLRTSTSGQSEPSNLKASSKRPTKAQSASGPVRPRQTSKQASLQTGFRELQDSPTASKRRKSPKEDKDSSGQSKMLFVPHQRDHQSSLISPPHGLFNGTHPSSSKTRPPETKGRVKQSPALISISSPSPECERGGSSGLSHRSDGFELKGRKRKTSGASPPKNTSCAPKANILSPLSQTHSGLVSWGGDGRPGSTSHSLTKKLAAQKPKLLH", "length": 666, "header": "tr|A5PMH0-1|A5PMH0_DANRE Isoform 1 of Ataxin-7-like protein 2b OS=Danio rerio OX=7955 GN=atxn7l2b PE=4 SV=1 CANONICAL=A5PMH0-1" }, "isoforms": [ { "isoform_ac": "A5PMH0-1", "url": "https://www.uniprot.org/uniprotkb/A5PMH0/entry#A5PMH0-1", "sequence": { "sequence": "MVADRARAKTVMAALDRRISILDYVGQSWAAWIDKANVSTPDGPPLEECSKNVKKRMETMTLKKEDMSIYGHCPAHDNFFLVVCSHCGQVVKPQAFEKHCERRHGPFSKLYGTPSNCSPDRPQQGRPPSSQHVSLCEGQDGRHQGAGPPRVPPPHPPHQGRPKPQREAPSLQPLDKVPHVKPPSPSDLPTPPKKALPSAEKPIIQKGLDSHGPRTYSRTFKKVLKKECDVNKHCGVMDPERKKVCTRLLTCNIHSIHQRRQVVGRRKPFDQLVMELKMSSKPRERPPLPREISDGGSVNHETPAPQTGPLHYKCQITNSSILRSVNPSEGVVEVKEEVMRSEETQAESLSAALSSEESDGENREEFAHLPASTLHPKPLGLCTFGARVLGRSVLAFDRRLLHLRSAFSVMMEQHLSTYLWKKLPQVSELCSNQQQITYNSHDATRSSAPIHITSTLRTSTSGQSEPSNLKASSKRPTKAQSASGPVRPRQTSKQASLQTGFRELQDSPTASKRRKSPKEDKDSSGQSKMLFVPHQRDHQSSLISPPHGLFNGTHPSSSKTRPPETKGRVKQSPALISISSPSPECERGGSSGLSHRSDGFELKGRKRKTSGASPPKNTSCAPKANILSPLSQTHSGLVSWGGDGRPGSTSHSLTKKLAAQKPKLLH", "length": 666, "header": "tr|A5PMH0-1|A5PMH0_DANRE Isoform 1 of Ataxin-7-like protein 2b OS=Danio rerio OX=7955 GN=atxn7l2b PE=4 SV=1 CANONICAL=A5PMH0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 190, "start_aa": "Thr", "end_pos": 190, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr190", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Hematopoietic gene expression profile in zebrafish kidney marrow.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2004", "authors": "Song Huai-Dong, Sun Xiao-Jian, Deng Min, Zhang Guo-Wei, Zhou Yi, Wu Xin-Yan, Sheng Yan, Chen Yi, Ruan Zheng, Jiang Chun-Lei, Fan Hui-Yong, Zon Leonard I, Kanki John P, Liu Ting Xi, Look A Thomas, Chen Zhu", "evidence": [ { "database": "UniProtKB", "id": "A5PMH0", "url": "https://www.uniprot.org/uniprotkb/A5PMH0" } ], "reference": [ { "type": "PubMed", "id": "15520368", "url": "https://glygen.org/publication/PubMed/15520368" } ] }, { "title": "The zebrafish gene map defines ancestral vertebrate chromosomes.", "journal": "Genome Res.", "date": "2005", "authors": "Woods Ian G, Wilson Catherine, Friedlander Brian, Chang Patricia, Reyes Daengnoy K, Nix Rebecca, Kelly Peter D, Chu Felicia, Postlethwait John H, Talbot William S", "evidence": [ { "database": "UniProtKB", "id": "A5PMH0", "url": "https://www.uniprot.org/uniprotkb/A5PMH0" } ], "reference": [ { "type": "PubMed", "id": "16109975", "url": "https://glygen.org/publication/PubMed/16109975" } ] }, { "title": "Requirement for zebrafish ataxin-7 in differentiation of photoreceptors and cerebellar neurons.", "journal": "PLoS ONE", "date": "2012", "authors": "Yanicostas Constantin, Barbieri Elisa, Hibi Masahiko, Brice Alexis, Stevanin Giovanni, Soussi-Yanicostas Nadia", "evidence": [ { "database": "UniProtKB", "id": "A5PMH0", "url": "https://www.uniprot.org/uniprotkb/A5PMH0" } ], "reference": [ { "type": "PubMed", "id": "23226359", "url": "https://glygen.org/publication/PubMed/23226359" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A5PMH0", "url": "https://www.uniprot.org/uniprotkb/A5PMH0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:436928", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:436928", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LP53-1", "protein_name": "Ataxin 7-like 2", "gene_name": "Atxn7l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAILSVQDLRRAELEESSKNTKKLDAMTLIKEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYARAPPPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDSLCLFVPVVNLEKMSSLPKPDGHGIRVAPPSAFLSQPGGLPKDSPGKVPTAPSPKEPPGRENMELIPGEGTSHRAEGSPPEKEPSGARLPPKTHRKMARKEFDLNRQCGVINPETKKICTRLLTCKIHSVHQRREVPGRAKDFDVLVAELKASSRKGESPKEKSPARKEPALERPSQEPPTAVQGAAAVAAPNNTFSSLSKQTYPYCTLPRSRASSESEVDDEGLCGGDGDPGLFPFPLPRGGAQASSEESEEEGTSDDLHLSPDCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSSHMWKKIPPAAEPPSHLVSPSLSDPLSPSSMGSCPRLPGPPPRPACPASVPPIKDSLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKEGVEMEAPSRKRKLSPGPTTFKRTCILEPAGKGKPSSCRGLSTKTKTALNLGLNGTVGPRMKRAGPLDCRGSPHSSPIPVKASQLENRGVAGHPTKVLPTNCLSEEEVAKKRKNLATYCRPVKAKHCQAGVPPDGTCSVRRKKPGPALPFEEKCSTLKVPVQLPEEHGQRGFGRG", "length": 735 }, "evidence": [ { "id": "HGNC:28713", "url": "https://alliancegenome.org/gene/HGNC:28713#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58GR47-1", "protein_name": "Ataxin-7-like protein 2a isoform X1", "gene_name": "atxn7l2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMAVRERAVKVMAALERRVPCLDDFVGQSWSVWTERANLTASEGSDGDEYSKNGKKTMETMTLRKEDMSIFGHYPGQDDFYLVVCSHCSQVVKPQAFEKHCERRHGPLGKLYAHLRSTPPPSQQQRPRHGHTPPSHGATASWSGRNQNVGPPRASPQSPATPPQFRHSKPPKDGVWHSPSNSSNSAHSESAVFKQPPPIEPTRSSPPPAHRDPPWPHGGPSPNRPPPAAERPQSQRGEAASAPVPSGHLRGTKTHKMVSKKECDLDKHCGVLDTERKKVCTRLLTCNIHSIHQRRKVQGRSKNFDQLVAELKMSSKARERVSQAPESSSAPSVSPEPPRDTPAPPSCRRPLTNSPAFRTPVSSESIEEDKTHLEESSTRAHSPLTQAHISGDESEGETNEEPADWHSTPWHPKPAALCSFGSHSLGHGVFTFDRRLHHLRSAMSAMVESHLSAHLWKKIPQASDPQSQSPQAKPAAVPASPSSISQHSKPRAGSHNTTSSLKTSFYSSHGPGKEPNPQSSSTSKAYAQSENSGSSKLGRSPSQSGPGRPKNPVGRPSKQQMRLRESDRTPTPDAAALRKRKASFEDSDSAVSPDKNCVPQNKSRPLISKTPPSASHGQTNGSLSPGSKARPSDSHSPSSWAFKRTHQSAPDSRGLDSGLRVSSFDHKSLGKKRKSSGSSPPSKPHRLPTSPHSGFYTWKESKGSGLSVGGEKKLSTQKIHLYKWAQTSFGWILFMYVFYLFIYLFIYLYFVINSELYIILEDILYMLIFY", "length": 770 }, "evidence": [ { "id": "HGNC:28713", "url": "https://alliancegenome.org/gene/HGNC:28713#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P53165-1", "protein_name": "SAGA complex subunit SGF73", "gene_name": "SGF73", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MRSGDAEIKGIKPKVIEEYSLSQGSGPSNDSWKSLMSSAKDTPLQYDHMNRESLKKYFNPNAQLIEDPLDKPIQYRVCEKCGKPLALTAIVDHLENHCAGASGKSSTDPRDESTRETIRNGVESTGRNNNDDDNSNDNNNDDDDDDDNDDNEDDDDADDDDDNSNGANYKKNDSSFNPLKRSTSMESANTPNMDTKRSKTGTPQTFSSSIKKQKKVKQRNPTEKHLIDFNKQCGVELPEGGYCARSLTCKSHSMGAKRAVSGRSKPYDVLLADYHREHQTKIGAAAEKRAKQQELQKLQKQIQKEQKKHTQQQKQGQRSKQRNVNGGKSAKNGGKSTVHNGNNINEIGHVNLTPEEETTQVLNGVSRSFPLPLESTVLSSVRYRTKYFRMREMFASSFSVKPGYTSPGYGAIHSRVGCLDLDRTTDYKFRVRTPQPINHLTNQNLNPKQIQRLQQQRALQAQLLSQQQQQQQQQQQHHSPQAQAQASTQQPTQGMVPNHFPGGATNSSFNANVSSKQIQQQQQQQQHKSQDTGLTPLEIQSQQQKLRQQQLQQQKFEAAASYLANATKLMQESNQDSHLSGTHNNNSSKNGNNNLMTMKASISSPNTSVNSIQSPPSVNSVNGSGQGVSTGINVSGNNGRIEVGIGNSVNPYNGRIN", "length": 657 }, "evidence": [ { "id": "HGNC:28713", "url": "https://alliancegenome.org/gene/HGNC:28713#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5T6C5-1", "protein_name": "Ataxin-7-like protein 2", "gene_name": "ATXN7L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVRERAAAAMAALERRVPSLDDFAGQSWSSWVERADLPAADGAELEESSKNTKKLDAMTLIKEDMSIFGHCPAHDDFYLVVCNHCSQVVKPQAFQKHCERRHGPLSKLYGRAPPPPPAPASSQKCHVVNGQGPACRAPGSTKTSSREKGQGSRSRGHQPPEKTQKDNLCQPGGLTKDSPGKPPMAPPSKEPPGRENIEIIPSEGSSHWAEGSPPEKEPSGTRLPPKTHRKMARKECDLNRQCGVINPETKKICTRLLTCKIHSVHQRREVQGRAKDFDVLVAELKANSRKGESPKEKSPGRKEQVLERPSQELPSSVQVVAAVAAPSSTFSVRAKQTYPYCALPRSRASSESELDDEGPCGGDGDPGLFPFPMPRGGTQASSEESEEEGTSDDLHPPPDCHYATRPPRPQAFCTFGSRLVSPGCYVFSRRLDRFCSALSSMLERHLSTHMWKKIPPAAEPPAHLVNSPLSAPLSPSSTGTCPRLPGPTLRPACPASMPPTKDNLVPSYPAGSPSVAAACSQAECMGGSQAITSPLPANTPSPSFSKLPPSKASKSSKGKDGVEVEAPSRKRKLSPGPTTLKRTCILEPTGKGKPSGCRGLSAKTKTALSMGLNGTMGPRVKRAGPLDCRGSPHQLPTPVKASQLENRGAAGHPAKALPTNCLSEEEVAKKRKNLATYCRPVKAKHCQAGAPADVACSVRRKKPGPALAFEEKCSTLKSKAH", "length": 722 }, "evidence": [ { "id": "HGNC:28713", "url": "https://alliancegenome.org/gene/HGNC:28713#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-403", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-403#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 37, "end_pos": 39, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 617, "end_pos": 619, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5PMH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMH0" }, { "id": "PS51505", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51505" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCA7", "eco_id": "ECO_0000259", "start_pos": 221, "end_pos": 288, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 190 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 37, "end_pos": 39 }, { "start_pos": 551, "end_pos": 553 }, { "start_pos": 617, "end_pos": 619 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5PMM7-1", "uniprot_ac": "A5PMM7", "uniprot_id": "A5PMM7_DANRE", "mass": { "chemical_mass": 42124.0, "monoisotopic_mass": 42124.0 }, "refseq": { "ac": "NP_001093504", "name": "uncharacterized protein LOC567837", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093504" }, "gene_names": [ { "name": "si:dkey-193c22.1", "type": "recommended", "evidence": [ { "id": "A5PMM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMM7" } ] }, { "name": "fj43c01", "type": "synonym", "evidence": [ { "id": "NP_001093504", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093504" }, { "id": "A5PMM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMM7" } ] }, { "name": "si:dkey-193c22.1", "type": "synonym", "evidence": [ { "id": "NP_001093504", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093504" } ] }, { "name": "wu:fj43c01", "type": "synonym", "evidence": [ { "id": "NP_001093504", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093504" }, { "id": "A5PMM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMM7" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC567837", "type": "synonym", "evidence": [ { "id": "A5PMM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMM7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC567837", "type": "synonym", "evidence": [ { "id": "NP_001093504", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093504" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01036935.1, SRR32588726.5517802.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000005.1. On Jun 7, 2025 this sequence version replaced NP_001093504.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001093504", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093504" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMM7", "url": "https://www.uniprot.org/uniprotkb/A5PMM7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-193c22.1", "url": "https://www.uniprot.org/uniprotkb/A5PMM7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-7957", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7957", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000093687", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000093687", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "567837", "url": "https://www.ncbi.nlm.nih.gov/gene/567837", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050300", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050300", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567837", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567837", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "STYCLLA", "url": "https://omabrowser.org/oma/group/STYCLLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5PMM7", "url": "https://www.orthodb.org/?gene=A5PMM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48081", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48081", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48081:SF33", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48081:SF33", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF20434", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20434", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001093504", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093504", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5PMM7", "url": "https://www.uniprot.org/uniprotkb/A5PMM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PMM7-1", "url": "https://www.uniprot.org/uniprotkb/A5PMM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-7957", "url": "https://zfin.org/ZDB-GENE-030131-7957", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MISLKCCVSIPAVAGALLVGLPYSISLVAQWLYGWPNKPGYQKYIEALKPRRIYCLARAVLEMLKYLQYGKLYFQWKLWYSNDKNNKHYVKGITFGRRGNKLDLYYSPRLELSDESPVPVVVFVYGGAWGSGDRSIYCLLALQMAKELNASVICPDYSIYPKGNVLNMVQDISDSLLWVRQKGHAFSLDQDNIILIGHSAGAHLCALTSLFLASNVEELFIETNKQKDLVTAIKGIIGLSGVYSIMDHYNHEKVRAVEYVSTMHKAMDGVENFDYYSPTSLLKKMKEDQLKRVPPMALFHGTNDIIVPVESSVRFSELLTSLSIRMSLYLIPKMNHTDMVTDLMAPDRHFYHTVYGCIKHEYSKFQTHTD", "length": 370, "header": "tr|A5PMM7-1|A5PMM7_DANRE Isoform 1 of Uncharacterized protein LOC567837 OS=Danio rerio OX=7955 GN=si:dkey-193c22.1 PE=4 SV=1 CANONICAL=A5PMM7-1" }, "isoforms": [ { "isoform_ac": "A5PMM7-1", "url": "https://www.uniprot.org/uniprotkb/A5PMM7/entry#A5PMM7-1", "sequence": { "sequence": "MISLKCCVSIPAVAGALLVGLPYSISLVAQWLYGWPNKPGYQKYIEALKPRRIYCLARAVLEMLKYLQYGKLYFQWKLWYSNDKNNKHYVKGITFGRRGNKLDLYYSPRLELSDESPVPVVVFVYGGAWGSGDRSIYCLLALQMAKELNASVICPDYSIYPKGNVLNMVQDISDSLLWVRQKGHAFSLDQDNIILIGHSAGAHLCALTSLFLASNVEELFIETNKQKDLVTAIKGIIGLSGVYSIMDHYNHEKVRAVEYVSTMHKAMDGVENFDYYSPTSLLKKMKEDQLKRVPPMALFHGTNDIIVPVESSVRFSELLTSLSIRMSLYLIPKMNHTDMVTDLMAPDRHFYHTVYGCIKHEYSKFQTHTD", "length": 370, "header": "tr|A5PMM7-1|A5PMM7_DANRE Isoform 1 of Uncharacterized protein LOC567837 OS=Danio rerio OX=7955 GN=si:dkey-193c22.1 PE=4 SV=1 CANONICAL=A5PMM7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "A5PMM7", "url": "https://www.uniprot.org/uniprotkb/A5PMM7" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] } ], "pathway": [ { "id": "dre:567837", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567837", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "hydrolase activity", "id": "GO:0016787", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016787", "evidence": [ { "database": "UniProtKB", "id": "A5PMM7", "url": "https://www.uniprot.org/uniprotkb/A5PMM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 335, "end_pos": 337, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5PMM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMM7" }, { "id": "PF20434", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20434" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BD-FAE-like", "eco_id": "ECO_0000259", "start_pos": 113, "end_pos": 318, "start_aa": "Ser", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 335, "end_pos": 337 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5PMV5-1", "uniprot_ac": "A5PMV5", "uniprot_id": "A5PMV5_DANRE", "mass": { "chemical_mass": 66079.0, "monoisotopic_mass": 66079.0 }, "refseq": { "ac": "NP_001093489", "name": "ferredoxin-fold anticodon-binding domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093489" }, "gene_names": [ { "name": "fdxacb1", "type": "recommended", "evidence": [ { "id": "A5PMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ] }, { "name": "fb11b09", "type": "synonym", "evidence": [ { "id": "NP_001093489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093489" }, { "id": "A5PMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ] }, { "name": "fdxacb1", "type": "synonym", "evidence": [ { "id": "NP_001093489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093489" } ] }, { "name": "si:dkey-71l1.3", "type": "synonym", "evidence": [ { "id": "NP_001093489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093489" }, { "id": "A5PMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ] }, { "name": "wu:fb11b09", "type": "synonym", "evidence": [ { "id": "NP_001093489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093489" }, { "id": "A5PMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ] } ], "protein_names": [ { "name": "phenylalanine--tRNA ligase", "type": "recommended", "evidence": [ { "id": "A5PMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMV5/entry#names_and_taxonomy" } ] }, { "name": "6.1.1.20", "type": "synonym", "evidence": [ { "id": "A5PMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMV5/entry#names_and_taxonomy" } ] }, { "name": "Phenylalanyl-tRNA synthetase", "type": "synonym", "evidence": [ { "id": "A5PMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMV5/entry#names_and_taxonomy" } ] }, { "name": "ferredoxin-fold anticodon-binding domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001093489", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093489" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01014591.1, GFIL01023890.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505380, SAMEA3505390 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jun 7, 2025 this sequence version replaced NP_001093489.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001093489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093489" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PMV5", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fdxacb1", "url": "https://www.uniprot.org/uniprotkb/A5PMV5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-8403", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8403", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000095750", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000095750", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "566022", "url": "https://www.ncbi.nlm.nih.gov/gene/566022", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005121", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005121", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019446", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019446", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036690", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036690", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045864", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045864", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566022", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566022", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IRFGVDC", "url": "https://omabrowser.org/oma/group/IRFGVDC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5PMV5", "url": "https://www.orthodb.org/?gene=A5PMV5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11538", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11538", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11538:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11538:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03147", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03147", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF10354", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10354", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001093489", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093489", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "19413", "url": "https://www.rhea-db.org/rhea/19413", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A5PMV5", "url": "https://www.uniprot.org/uniprotkb/A5PMV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PMV5-1", "url": "https://www.uniprot.org/uniprotkb/A5PMV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-8403", "url": "https://zfin.org/ZDB-GENE-030131-8403", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSKTREVLLVGEGNFSFSAALSETGGDDVGVTATCFQSENETYRQEGVALNVQRLRERGSVVLFEVDCTCLKEHEALQDHLFDCVIFNFPHCGRKSGVKKNRVLLMKFFLSAVAVLKDNGEVHVTLCNGQGGTPCDSPMREWHNSWQVVAMAAEAGLILREIRPFECEMYQGYRCTGYRSQDKGFHVEGALTHIFTSSLPHTMPEKLKMEKTVGKETVCFELPAELSNYINRNFLGQQSHHPVKTVQEQLHRELKSVWPVCTINEDFPELVYCLPEMLEACDPTLTHSEVYWIKPTDTYVFDQSETKQNDCESTDDQQSFTGSYALRPSLLLHVQEITQNEDFSPGTLYAVSGLVFQRVPICPIRSPAFHQLLLVGMFPVESHPLRCFQDSLESLLIPYDVSFEEVQTGLEQQVWINSKMLPKFGRITYLPSISSAVDEGLQLVAVSVNLDHLATLIFGISDWRLLWSADPRFLKHFELSPSGPFSPFSLYPPSYLHDISFWMDPENYDELDFHAIVREASCGVVKNVALVDRFRHPHMGHASLCYRLTYQSSDRALSNSQVLALQNQLRRLLALRMQVTLR", "length": 582, "header": "tr|A5PMV5-1|A5PMV5_DANRE Isoform 1 of phenylalanine--tRNA ligase OS=Danio rerio OX=7955 GN=fdxacb1 PE=3 SV=1 CANONICAL=A5PMV5-1" }, "isoforms": [ { "isoform_ac": "A5PMV5-1", "url": "https://www.uniprot.org/uniprotkb/A5PMV5/entry#A5PMV5-1", "sequence": { "sequence": "MSKTREVLLVGEGNFSFSAALSETGGDDVGVTATCFQSENETYRQEGVALNVQRLRERGSVVLFEVDCTCLKEHEALQDHLFDCVIFNFPHCGRKSGVKKNRVLLMKFFLSAVAVLKDNGEVHVTLCNGQGGTPCDSPMREWHNSWQVVAMAAEAGLILREIRPFECEMYQGYRCTGYRSQDKGFHVEGALTHIFTSSLPHTMPEKLKMEKTVGKETVCFELPAELSNYINRNFLGQQSHHPVKTVQEQLHRELKSVWPVCTINEDFPELVYCLPEMLEACDPTLTHSEVYWIKPTDTYVFDQSETKQNDCESTDDQQSFTGSYALRPSLLLHVQEITQNEDFSPGTLYAVSGLVFQRVPICPIRSPAFHQLLLVGMFPVESHPLRCFQDSLESLLIPYDVSFEEVQTGLEQQVWINSKMLPKFGRITYLPSISSAVDEGLQLVAVSVNLDHLATLIFGISDWRLLWSADPRFLKHFELSPSGPFSPFSLYPPSYLHDISFWMDPENYDELDFHAIVREASCGVVKNVALVDRFRHPHMGHASLCYRLTYQSSDRALSNSQVLALQNQLRRLLALRMQVTLR", "length": 582, "header": "tr|A5PMV5-1|A5PMV5_DANRE Isoform 1 of phenylalanine--tRNA ligase OS=Danio rerio OX=7955 GN=fdxacb1 PE=3 SV=1 CANONICAL=A5PMV5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A5PMV5", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:566022", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566022", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LPK9-1", "protein_name": "Ferredoxin-fold anticodon binding domain containing 1", "gene_name": "FDXACB1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAPRRLLLVGEGNFSFAVALSETLDPNTSLTATCPQRSADLARDLVVRENLRRLRERGNEVRFGVDCTHLADAFEPQDREFDRIYFNFPHCGRKAGVAKNRELLAKFFRSCADVLAEDGEVHVALCRGQGGTPADKPMREWHNSWQVVAMAALGGFILSDVHPFNCKALPGYKCTGYRSQDKSFHIEGALNHIFTRSLPFESLQPRISRIKLGDQWFSFLEPEVLVGKLNRGFLEAPSCHPIKTINEKLIAELGKAFPLKRLKCSSPLLLQGDASVLTSHNPDILSTAFWVSLHEDNSNFESLTSGITQYMEDFLVSFSELSLPKSARRDSKEEAHEGTFGQAKVCLRPSLLVHIQAVIQAPDFLPGSLHILSGPVFQRCCISPFTMPAFHETLYILGFNKNLKDSCVQSLLDHLKGILDNLLTQTWLEGSERSSSVEFVFQPTGERYMITVKSQNFGPDCVKDLIIGSVTTSATSVIHKDQCFVCVCMNLDLLAMLVWDISDWRMLWTSDSRFLKNFAPGKIEPFKSYSLYPPYYVHDISFWLDEKKRFDEVEFHTLARAVSQDTVISIQFLSRFQHPKTEQVSLCYRLTYQTCDKALTQKQVASMQSQLRKEIQQRLHVTPR", "length": 624 }, "evidence": [ { "id": "A5PMV5", "url": "https://omabrowser.org/oma/group/A5PMV5/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0ZWR6-1", "protein_name": "phenylalanine--tRNA ligase", "gene_name": "FDXACB1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAERRVLLLGEGNFSFAAALCEAAGTRVVATCYEREEEVAARGRAAESIRRLRERGAEVMFSVDCTKLKDYFLPAKREFDCIYFNFPHCGRKAGVVKNRELLARFFHSCAEVLTRDGEVHVALCRGQGGTPADQPRREWHNSWQVVAVAAGAGFILSDVHPFRAETARGYECTGYRSQDKSFCIEGALNHVFTQSTPLLYCKPLICEIELERQRISFQVPQVLVDKINRGFLEQNSNHPVRTIKEKLTAVLSQAFPLQSIDCCLSLLLQGDLDAACHSNIFWILLSLEETPSAEEMATGRANAIVFSHVDFHRDTDKNVQEGCQTPKQCYLRPSLLPYAQAIIKSAAFVPGTLYVFSGPVFRKCRISPYCTPVFHEMVFVCAVNRGSENSCIQMIVDKIKTSIHSLHQTISDFKLSISLQKATSLGTAELSDFAAFESQLGKIQFFLCIEADTRDSSEKGSCVGAVRTAPYEPAGSDLVVVFASLNLDLMAMLICAIDDWRMLWTSDARFLCQFPAGELRIFRSFSLYPPSYVHDVSFWLPDGEQFDDVAFHTIAREVSGEAVASIHLLDKFQQLGTGRTSLCCRLTFQSCDRALGRGDVAAMQLRFREEISQRLRVALR", "length": 620 }, "evidence": [ { "id": "A5PMV5", "url": "https://omabrowser.org/oma/group/A5PMV5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LJG1-1", "protein_name": "Mannosyltransferase", "gene_name": "Alg9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MCALEIAVREPEEAMVPRRLLLVGEGNFSFAASLIDGLDPDVSVTATGFQHRADLEGDPVALENLRRLRERGVEVRFGVDCTQLADEREFDRIYFNFPHCGRKAGVAKNRELLAKFFQSCADVLAKEGEVHVALCRGQGGTPADKPQREWHNSWQVVAMAALGGLILSDVCPFSCEAVPGYKCTGYRSQDRPFHIEGALTYIFTQSLPFESSRPRTFRVRLEDRWFYFTEPEALLGKLNRRFLEAPSCHPIRTINEKLIAELGKTFPLKRLRCPLPLLSQGGPSVLPPVACDLLPTFWICLHEDSSCSELLNGEITEDMEEIPDSGSECTLPKSPARDGCKAAQEGVCEQVKLRLRPSLLVHAEPVIHSPEFLPGSLYVLSGPVFRKCHILPFTMPAFHETLFILGFNRNTKESCLLPLLDHLKDTLGMASRRARQRLKGGGGGGGGSGGGSGSGGDAGPAAEKLRELLGSREAGVEPRPESGNKAGQVWAPEGSTAFKCLLSARLCAALLSNISDCDETFNYWEPTHYLIYGKGFQTWEYSPVYAIRSYAYLLLHAWPAAFHARILQTNKILVFYFLRCLLAFVSCVCELYFYKAVCKKFGLHVSRMMLAFLVLSTGMFCSSSAFLPSSFCMYTTLVAMTGWYMDKTPIAVLGVAAGAILGWPFSAALGLPIAFDLLAMKHRWKSFFLWSLAALVLFLVPVVVIDSYYYGKLVIAPLNIVLYNVFTSHGPDLYGTEPWYFYLINGFLNFNVAFALALLVLPLTFLMEYLLQRFHVQNLGHPYWLTLAPMYIWFMIFFIQPHKEERFLFPVYPLICLCGAVALSALQKCYHFVFQRYRLEHYTVTSSWLALGTVFLFGLLSFSRSVALFRGYHGPLDLYPEFYRIATDPTIHTVPEGRPVNVCVGKEWYRFPSSFLLPDNWQLQFIPSEFRGQLPKPFAEGPLATRIVPAHMNDQNREEPSRYIDISKCHYLVDVDTMRETPREPNYSSNREEWVSLAHRPFLDASRSSKLLRAFYIPFLSDQYTVYVNYTILKPRKAKQSRKKSGG", "length": 1047 }, "evidence": [ { "id": "MGI:3584513", "url": "https://alliancegenome.org/gene/MGI:3584513#orthology", "database": "AGR" }, { "id": "HGNC:25110", "url": "https://alliancegenome.org/gene/HGNC:25110#orthology", "database": "AGR" }, { "id": "A5PMV5", "url": "https://omabrowser.org/oma/group/A5PMV5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "I3LCK5-1", "protein_name": "Ferredoxin-fold anticodon binding domain containing 1", "gene_name": "FDXACB1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPRRLLLVGEGNFSFAVALNQTLDPRTSLTATCLQRPADLAQDPVAQENLQRLRERGAEIRFGVDCTQLVDAFELQDREFDRIYFNFPHCGRKAGVAKNRELLAKFFQSCADVLAEEGEVHVALCKGQGGTPADKPMREWHNSWQVVAMAALGGFILSDVHPFSCEAVPGYKCTGYRSQDKSFHVEGALNHIFTRSLAFEDLQPRISRIKLSDQWFSFLEPEVLAGKLNRGFLEAPSCHPVKTINEKLIGELGKAFPLKRLTCPSPLLPQGGTSVLTVGNCDVLLSSAFWISLCEDNSYSEFLTGGTTQDTEDFLVSFSELSLPRCPGRDSKEAAQEGMYDQAKICLRPSLLVHVQVVIQAPDFLPGSLHILSGPVFQKCLISPFTMPAFHETLFILGFDKNLKDGCLQSLLDHLNGILNSLLNQTLLEGSELSSSVEFVFEPNGKDYMVNVKSHNFGSDCIKDLIIGSVTTSATSIIHKDLCFVCVSVNLDLLAMLVWGISDWRMLWTFDNRFLKNFSPGKIAPFKSYSLYPPYYVHDISFWLDEKKSFDEVEFHTVARAVSQDTVISIQFLSRFQHPKTEQVSLCYRLTYQTCDKALTQQQVASMQSQLRKAIQQQLHVTPR", "length": 625 }, "evidence": [ { "id": "A5PMV5", "url": "https://omabrowser.org/oma/group/A5PMV5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "P40493-1", "protein_name": "25S rRNA (uridine(2634)-N(3))-methyltransferase", "gene_name": "BMT5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MARKLKGKIGSKGLKGALLRHKAKVKLVRNIESKQKHELRKKNSSANNKTVKRNQEFQKLNQGKVMPFEKDETLMLCGEGDFSFARSIVEQNYIESDNLIITSYDNSVNELKLKYPHTFEENYQYLKDLNIPIFFQIDVTKLVKSFKISKNNTWFKIINRLSDHRWGNKPLQNIVFNFPHNGKGIKDQERNIREHQDLIFNFFQNSLQLFNLINTKIQNDTLRYTQGYDLNEDTPQAKKLTAEGYGNIILSLFDGEPYDSWQIKLLAKKNGLTLSRSSKFQWENFPGYHHRRTNSEQDTTKPAKERDARFYIFSKYVSNSSKHNRKSKKDTDSDSD", "length": 336 }, "evidence": [ { "id": "MGI:3584513", "url": "https://alliancegenome.org/gene/MGI:3584513#orthology", "database": "AGR" }, { "id": "HGNC:25110", "url": "https://alliancegenome.org/gene/HGNC:25110#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3UY23-1", "protein_name": "Ferredoxin-fold anticodon-binding domain-containing protein 1 homolog", "gene_name": "Fdxacb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPRRLLLVGEGNFSFAASLIDGLDPSVSVTATGFQHRAALEGDPVALENLKRLRERGVEVRFGVDCTQLSHALPADDRDFDRIYFNFPHCGRKAGVAKNRELLAKFFQSCADVLAKAGEVHVTLCRGQGGTPADKPQREWHNSWQVVAMAALGGFILSDVCPFSCEAVPGYKCTGYRSQDRPFHIEGALTYIFTQSLPFESCQPRTFRVRLEDRWFYFTEPEALPGKLNRRFLEASSCHPIRTINEKLIAELGKTFPLKRLKCPLPLLSRGGPSVFLPATCDLLPTFWIRLHEDNSCSEFQNGEITQEMEEIPVSVSECTLPESPVRDGCKGAQEGICGRVKLGLRPSLLVHVEAVIHSPDFLPASLHVLSGPVFRKCHILPFMMPAFHETLFILGFDNNMKESCLPSLLGHLKDALGNLLTQTLQEGSSLGTSVEFVLQPNGKDYIIHVKSLNFGPDCAENLIIGSILTSKIVKHKHQCFVFVSINLDLLVMLAYGISDWRILWTFDNRFLKRFAPGKIEHFKSYSLYPPCYVHDVSFWVDEKKAFDELEFHTVARAVSQDTVVSVQYRDRFQHPETRQVSLCYRLTYQTCDKALTPQLAAAMQSQFRKEIQRQLHVSPR", "length": 622 }, "evidence": [ { "id": "MGI:3584513", "url": "https://alliancegenome.org/gene/MGI:3584513#orthology", "database": "AGR" }, { "id": "HGNC:25110", "url": "https://alliancegenome.org/gene/HGNC:25110#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-8403", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8403#orthology", "database": "AGR" }, { "id": "A5PMV5", "url": "https://omabrowser.org/oma/group/A5PMV5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BRP7-1", "protein_name": "Ferredoxin-fold anticodon-binding domain-containing protein 1", "gene_name": "FDXACB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPRRLLLVGEGNFSFAAALSETLDQSTQLTATCLQRPAELARDPLAWENLQCLRERGIDVRFGVDCTQLADVFELHEREFDQIYFIFPHCGRKAGVAKNRELLAKFFQSCADVLAEEGEVHVALCRGQGGTPADKPQREWHNSWQVVAMAALGGLILSDVYPFSCKAVAGYKCTGYRSQDKSFHVEGALNHIFTRSLPFEGSQPRIFRIKLGNQWFSFPEPEALVGKLNRGFLEAPSCHPIKTINEKLIAELGKVFPLKRLKCSYPLLPQEGTSVLPFWNCDFLSAAFWISLHEDNSNSESLTGGTSQDVEDFLVSFSELSLLKNPGRDGKEEACEGTCGQAKICLRPSLLVHVQDVIEVPDFLSGSLHILSGPVFQKCHILPFTMPAFHETLFILGVNQNLKDGCLQSLLDHLKGILDSLLTQTLPESSKLSSLVKFVLQSNGKDYMIRVKTHNFSPDCTEDLIIGSVITSATSVIHKDQCFVFVSMNLDLLAMLVWCISDWRMLWTFDNRFLKNFVPGKIEPFKSHSLYPPCYVHDVSFWIDQKKGFDELEFHTVARAVSQDTIISIQFLSRFQHPKTQQVSLCYRLTYQTCDKALTQQQVASMQSQFRKEIQQHLYVIPR", "length": 624 }, "evidence": [ { "id": "MGI:3584513", "url": "https://alliancegenome.org/gene/MGI:3584513#orthology", "database": "AGR" }, { "id": "HGNC:25110", "url": "https://alliancegenome.org/gene/HGNC:25110#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-8403", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8403#orthology", "database": "AGR" }, { "id": "A5PMV5", "url": "https://omabrowser.org/oma/group/A5PMV5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "A5PMV5", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ], "pmid": "" }, { "name": "rRNA (uridine-N3-)-methyltransferase activity", "id": "GO:0070042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070042", "evidence": [ { "database": "UniProtKB", "id": "A5PMV5", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ], "pmid": "" }, { "name": "phenylalanine-tRNA ligase activity", "id": "GO:0004826", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004826", "evidence": [ { "database": "UniProtKB", "id": "A5PMV5", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "A5PMV5", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ], "pmid": "" }, { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "A5PMV5", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "translation", "id": "GO:0006412", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006412", "evidence": [ { "database": "UniProtKB", "id": "A5PMV5", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ], "pmid": "" }, { "name": "rRNA base methylation", "id": "GO:0070475", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070475", "evidence": [ { "database": "UniProtKB", "id": "A5PMV5", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "19413", "name": "", "equation": "tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q1JPX3-1", "A5PMV5-1" ], "evidence": [ { "id": "19413", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/19413" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A5PMV5", "gene_name": "fdxacb1", "activity": [ { "ec_number": "6.1.1.20", "activity": "tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+).", "evidence": [ { "id": "A5PMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ] }, { "ec_number": "6.1.1.20", "activity": "", "evidence": [ { "id": "A5PMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" } ] } ] }, { "uniprot_ac": "Q1JPX3", "gene_name": "farsa", "activity": [ { "ec_number": "6.1.1.20", "activity": "tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+).", "evidence": [ { "id": "Q1JPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPX3" } ] }, { "ec_number": "6.1.1.20", "activity": "", "evidence": [ { "id": "Q1JPX3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q1JPX3" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5PMV5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PMV5" }, { "id": "PS51447", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51447" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FDX-ACB", "eco_id": "ECO_0000259", "start_pos": 490, "end_pos": 582, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "6.1.1.20", "ec_name": "tRNA(Phe) + L-phenylalanine + ATP = L-phenylalanyl-tRNA(Phe) + AMP + diphosphate + H(+).", "evidence": [ { "id": "6.1.1.20", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:6.1.1.20" }, { "id": "6.1.1.20", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=6.1.1.20" } ] } ], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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The reference sequence was derived from JBMGRA010000019.1. 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Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A5PN01", "url": "https://www.uniprot.org/uniprotkb/A5PN01" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A5PN01", "url": "https://www.uniprot.org/uniprotkb/A5PN01" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:566469", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566469", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "A5PN01", "url": "https://www.uniprot.org/uniprotkb/A5PN01" } ], "pmid": "" }, { "name": "basic amino acid transmembrane transporter activity", "id": "GO:0015174", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015174", "evidence": [ { "database": "UniProtKB", "id": "A5PN01", "url": "https://www.uniprot.org/uniprotkb/A5PN01" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "A5PN01", "url": "https://www.uniprot.org/uniprotkb/A5PN01" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "A5PN01", "url": "https://www.uniprot.org/uniprotkb/A5PN01" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 304, "end_pos": 306 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { 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The reference sequence was derived from JBMGRA010000005.1. On Jan 3, 2009 this sequence version replaced NP_001083001.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001083001", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083001" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5PN19", "url": "https://www.uniprot.org/uniprotkb/A5PN19" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A5PN19", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070410-141", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070410-141", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000078911", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000078911", "database": "Bgee", "categories": [ "Gene Expression" ] 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013170", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013170", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035967", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035967", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051485", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051485", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100037380", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100037380", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EYDNHER", "url": "https://omabrowser.org/oma/group/EYDNHER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5PN19", "url": "https://www.orthodb.org/?gene=A5PN19", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23140:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23140:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01805", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01805", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF04818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF08312", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08312", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001083001", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083001", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58JGW4", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JGW4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JGW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PN19", "url": "https://www.uniprot.org/uniprotkb/A5PN19", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5PN19-1", "url": "https://www.uniprot.org/uniprotkb/A5PN19-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070410-141", "url": "https://zfin.org/ZDB-GENE-070410-141", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MADKKGKSVAVKRTLTKKEQEEMKKKEEEKAAEVFEEFLAAFDTNDKSGVKTFVRGGIVNATKEEEAAEVKKSKLYRPSAKFSAPLQNTSPVHHAEVKKAVAKKKVEEKKKSNLELFKEELKQIQEEREERYKRKKGDSGAVFLGDLEPLTRRSIFDDDPAVPNTTNLYIGCINPKMTEEMLCKEFGKYGPLASVKIMWPRTEEERTRVTNRGFVAFMTRKDAERALAALDGKTVMGFEMKLGWGKAVRIPPQPLYTPIGVLKTTAPPPPSGLPFNAQPRDRFRNDFTKPRSRSQDDFYKTLSEAVVTVVIPPERNLLGLIHRMIEFVVREGPMFEAMIMNREKNNPDFRFLFDNKSQEHVYYRWKLYSILQGENPNNWRTSSFRMFRGGSLWKPPLLNPYLHGDEEPEEASFPSPEEEPKKGQLKSEHREKLEVLLRGLTPRRDEIGDAMLFCLERAEAAEEIVSCITESLSIAHTPLQKKIARLYLISDILYNSCAKVANASYYRKFFETKLPEIFGDISEAYRNIQARLQAEQFKQRIMGCFRAWEDWAVYPDSFLIQLQNIFLGLIKPGEEVIERPEPESPDLDGAPLDGVPLDRGEIDGTPLDDLDGSPLTWDPSAIDGVPVDDIDGVPLGNSVDDIDGVPFDEGSDKTLPTVALSKWEKVDDSESSAKNDSDNEVNSGGLKENSGDSDTSSDEADSPSRFEGADFKSSLKNFELSESKRTRLRELEVKVMNFQDELESGKRQRKSSLTLQQQVQHYRNRLLQKEFDKDDQEKRDKHSQKQKDRSKKDERRDKGEERSKTRDKEKSRKSEDREKSRGRSRDKEDRRERTKSRSPRKSKRSRSPSPQHKSWRSSSRSPHRSHKKSKKSKH", "length": 874, "header": "tr|A5PN19-1|A5PN19_DANRE Isoform 1 of Uncharacterized protein LOC100037380 OS=Danio rerio OX=7955 GN= PE=1 SV=1 CANONICAL=A5PN19-1" }, "isoforms": [ { "isoform_ac": "A0AC58JGW4-1", "url": "https://www.uniprot.org/uniprotkb/A5PN19/entry#A0AC58JGW4-1", "sequence": { "sequence": "MTSPNHAAAHRTTFTRNLLGLIHRMIEFVVREGPMFEAMIMNREKNNPDFRFLFDNKSQEHVYYRWKLYSILQGENPNNWRTSSFRMFRGGSLWKPPLLNPYLHGDEEPEEASFPSPEEEPKKGQLKSEHREKLEVLLRGLTPRRDEIGDAMLFCLERAEAAEEIVSCITESLSIAHTPLQKKIARLYLISDILYNSCAKVANASYYRKFFETKLPEIFGDISEAYRNIQARLQAEQFKQRIMGCFRAWEDWAVYPDSFLIQLQNIFLGLIKPGEEVIERPEPESPDLDGAPLDGVPLDRGEIDGTPLDDLDGSPLTWDPSAIDGVPVDDIDGVPLGNSVDDIDGVPFDEGSDKTLPTVALSKWEKVDDSESSAKNDSDNEVNSGGLKENSGDSDTSSDEADSPSRFEGADFKSSLKNFELSESKRTRLRELEVKVMNFQDELESGKRQRKSSLTLQQQVQHYRNRLLQKEFDKDDQEKRDKHSQKQKDRSKKDERRDKGEERSKTRDKEKSRKSEDREKSRGRSRDKEDRRERTKSRSPRKSKRSRSPSPQHKSWRSSSRSPHRSHKKSKKSKH", "length": 575, "header": "tr|A0AC58JGW4-1|A0AC58JGW4_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=zgc:163098 PE=1 SV=1 CANONICAL=A5PN19-1" }, "locus": {} }, { "isoform_ac": "A5PN19-1", "url": "https://www.uniprot.org/uniprotkb/A5PN19/entry#A5PN19-1", "sequence": { "sequence": "MADKKGKSVAVKRTLTKKEQEEMKKKEEEKAAEVFEEFLAAFDTNDKSGVKTFVRGGIVNATKEEEAAEVKKSKLYRPSAKFSAPLQNTSPVHHAEVKKAVAKKKVEEKKKSNLELFKEELKQIQEEREERYKRKKGDSGAVFLGDLEPLTRRSIFDDDPAVPNTTNLYIGCINPKMTEEMLCKEFGKYGPLASVKIMWPRTEEERTRVTNRGFVAFMTRKDAERALAALDGKTVMGFEMKLGWGKAVRIPPQPLYTPIGVLKTTAPPPPSGLPFNAQPRDRFRNDFTKPRSRSQDDFYKTLSEAVVTVVIPPERNLLGLIHRMIEFVVREGPMFEAMIMNREKNNPDFRFLFDNKSQEHVYYRWKLYSILQGENPNNWRTSSFRMFRGGSLWKPPLLNPYLHGDEEPEEASFPSPEEEPKKGQLKSEHREKLEVLLRGLTPRRDEIGDAMLFCLERAEAAEEIVSCITESLSIAHTPLQKKIARLYLISDILYNSCAKVANASYYRKFFETKLPEIFGDISEAYRNIQARLQAEQFKQRIMGCFRAWEDWAVYPDSFLIQLQNIFLGLIKPGEEVIERPEPESPDLDGAPLDGVPLDRGEIDGTPLDDLDGSPLTWDPSAIDGVPVDDIDGVPLGNSVDDIDGVPFDEGSDKTLPTVALSKWEKVDDSESSAKNDSDNEVNSGGLKENSGDSDTSSDEADSPSRFEGADFKSSLKNFELSESKRTRLRELEVKVMNFQDELESGKRQRKSSLTLQQQVQHYRNRLLQKEFDKDDQEKRDKHSQKQKDRSKKDERRDKGEERSKTRDKEKSRKSEDREKSRGRSRDKEDRRERTKSRSPRKSKRSRSPSPQHKSWRSSSRSPHRSHKKSKKSKH", "length": 874, "header": "tr|A5PN19-1|A5PN19_DANRE Isoform 1 of Uncharacterized protein LOC100037380 OS=Danio rerio OX=7955 GN= PE=1 SV=1 CANONICAL=A5PN19-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A5PN19", "url": "https://www.uniprot.org/uniprotkb/A5PN19" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100037380", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100037380", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZXP5-1", "protein_name": "U2 snRNP-associated SURP motif-containing protein", "gene_name": "U2surp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADKTPGGSQKASSKSRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESGRESLCDSPHQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKDEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRSMDVPSRRNRSSGVLDDYAPGSHDVGDPSTTNLYLGNINPQMNEEMLCQEFGRFGPLASVKIMWPRTDEERARERNCGFVAFMNRRDAERALKNLNGKMIMSFEMKLGWGKAVPIPPHPIYIPPSMMEHTLPPPPSGLPFNAQPRERLKNPNAPMLPPPKNKEDFEKTLSQAIVKVVIPTERNLLALIHRMIEFVVREGPMFEAMIMNREINNPMFRFLFENQTPAHVYYRWKLYSILQANSPTKWRTEDFRMFKNGSFWRPPPLNPYLHGMSEEQETEAFVEEPSKKGALKEEQRDKLEEILRGLTPRKNDIGDAMVFCLNNAEAAEEIVDCITESLSILKTPLPKKIARLYLVSDVLYNSSAKVANASYYRKFFETKLCQIFSDLNATYRTIQGHLQSENFKQRVMTCFRAWEDWAIYPEPFLIKLQNIFLGLVNIIEEKETEDVPDDLDGAPIEEELDGAPLEDVDGIPIDATPIDDLDGVPIKSLDDDLDGVPLDAAEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPVREEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDASKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNKH", "length": 1029 }, "evidence": [ { "id": "RGD:1307882", "url": "https://alliancegenome.org/gene/RGD:1307882#orthology", "database": "AGR" }, { "id": "MGI:1915208", "url": "https://alliancegenome.org/gene/MGI:1915208#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070410-141", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070410-141#orthology", "database": "AGR" }, { "id": "HGNC:30855", "url": "https://alliancegenome.org/gene/HGNC:30855#orthology", "database": "AGR" }, { "id": "FB:FBgn0034572", "url": "https://alliancegenome.org/gene/FB:FBgn0034572#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9QCG7-1", "protein_name": "U2 snRNP-associated SURP motif-containing protein", "gene_name": "u2surp", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MADKTPGGAQKGNSKALLESKLKAFSIGKMAVAKRTLSKKEQDEIKKKEDERAAAEIYEEFLAAFEGGEGKVKTFVRGGIANATKEEAAADEKKGKLYKPKSRIVEAKSFLPLETPQQFLPIDKRNASKKGDKEKKKSNLELFKEELKQIQEERDERHRLKGRVSRFEPLPTTEGRRSSDGSSRRNRPSSVLDDSAPGSHDVGDPTTTNLYLGNINPQMNEEMLCQEFGRYGPLASVKIMWPRTDEERARERNCGFVAFMTRRDAERALKHLNGKMIMNFEMKLGWGKGVPIPPHPIYIPPSMMEHTLPPPPSGLPFNAQPKERLKNPNAAMPPPPKCKEEFEKTLSQAIVKVVIPTERNLLSLIHRMIEFVVREGPMFEAMIMNREINNPLYRFLFENQSPAHVYYRWKLYTILQGESPTKWKTEDFRMFKNGSLWRPPPLNPYLHGTPEDEEHEDDDDEEICKKGSLKDEERDKLEELLRGLTPRKSDIAGGMFFCLTHADAAEEIVECIAESLSILKTPLPKKIARLYLVSDVLYNSSAKVTNASYYRKFFETKLCQIFSDLNATYKTIQGHLQSENFKQRVMSCFRAWEEWAVYPDPFLIKLQNIFLGLVSLDPEKEPEELVPELPEKVEDIDGAPIVEEELDGAPLDDVDGMPIDGAPIDGASMDDLDGMPIKGADDDLDGVPLDQKPGFKVAPSKWEAVDGAALEAQAVTTSKWEIFDLPEESEKSKSSTKSEAEGKNSHKSSSAADQQSYSNPVREEYDLKSAKFSETSEEKRAKLREIELKVMKFQDELESGKRPKKSGQSIQEQVELYRDKLLQREKEKETEKDKEKEKEKERKDKEKSDVFHKEKDKDESTPGRKEKKRRHSPSPSPTRSSSSRRGRSPSPRSERSDRSYTRDSSRSAYKDSPRESNRKSSKRSPSPPRTPKRSRRSRSRTPKKASKKSRSRSRSPHRSHKKSKKSKH", "length": 968 }, "evidence": [ { "id": "MGI:1915208", "url": "https://alliancegenome.org/gene/MGI:1915208#orthology", "database": "AGR" }, { "id": "HGNC:30855", "url": "https://alliancegenome.org/gene/HGNC:30855#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F4KIA8-1", "protein_name": "Protein RRC1-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MVKDEFFLDHPGRKHRSRNTEKKKKPRRRERRMKQLVCIKSPWNRFKGIMLQLRLLLEVTINPNDNKLKPDSQGEKSRDGDSISKKGSRYVPSFLPPPLASKGKGPENKRDEERSKEMEKGKTRNIDHFVEELKREQEIRERRNQDRENSRDHNSDNTSSSRFDELPDYFDPSGRLGSLDDGDPQTTNLYVVNLSSKVDENFLLRTFGRFGPIASVKIMWPRTEEEKRRERHCGFVAFMNRADGEAAKEKMQGIIVYEYELKIGWGKVVFLPSQALPAPPPGHMAIRSKEGCNLIFSVTSGPPMNSVPNQNSELVLTPNVPDITVISPEDEHLKQIIDTMALNVLDGGCAFEQAIMERGRGNPLFNFLFELGSKEHTYYVWRLYSFAQGDTLQRWRTEPYIMIAGSGRWIPPPLPATRSPEHGKESRGTYAAGKSRCTEAEQTLTDSQRDEFEDMLRALTLERSQIREAMGFALDNAEAAGEVVEVLTESLTLKETSIPTKVARLMLVSDIIHNSSARVKNASAYRTKFEATLPDIMESFNDLYHSVHGRITAEALRERVLKVLQVWADWFLFSDAYINGLRATFLRSRNFGVTSFHSICGDAPDIEKKGLIGNMNDADKINQDAALAMGEGAARQELMNRPISELERRCRHNGLSLLGGREMMVARLVCLKDAEKQRGYEVVDENAKYRQGHSTWEEVNIEPKRMKTSYDKVETEEPVDLASTIPIPQPELKAFVKKEKIDLILPTSRWAREDDETDDEQKKSYSSGSDNAGGITFKTDEEDLKADPSVRVQPENEIDVEQRQKLRHIEIALIEYRESLEEQGMKNSEEIERKVAIHRKRLEADGLSGNQRVLPEKREKREDSRDSSRKRNRSESQNRSQSPPQKSLTRERVRDHDLDKDRHRDRDRQQHDLDKDRKRRAKSSSRERDDHDRSRERDRDWRRRGMR", "length": 947 }, "evidence": [ { "id": "A5PN19", "url": "https://omabrowser.org/oma/group/A5PN19/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O15042-1", "protein_name": "U2 snRNP-associated SURP motif-containing protein", "gene_name": "U2SURP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADKTPGGSQKASSKTRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESARESLCDSPHQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKEEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRSMDAPSRRNRSSGVLDDYAPGSHDVGDPSTTNLYLGNINPQMNEEMLCQEFGRFGPLASVKIMWPRTDEERARERNCGFVAFMNRRDAERALKNLNGKMIMSFEMKLGWGKAVPIPPHPIYIPPSMMEHTLPPPPSGLPFNAQPRERLKNPNAPMLPPPKNKEDFEKTLSQAIVKVVIPTERNLLALIHRMIEFVVREGPMFEAMIMNREINNPMFRFLFENQTPAHVYYRWKLYSILQGDSPTKWRTEDFRMFKNGSFWRPPPLNPYLHGMSEEQETEAFVEEPSKKGALKEEQRDKLEEILRGLTPRKNDIGDAMVFCLNNAEAAEEIVDCITESLSILKTPLPKKIARLYLVSDVLYNSSAKVANASYYRKFFETKLCQIFSDLNATYRTIQGHLQSENFKQRVMTCFRAWEDWAIYPEPFLIKLQNIFLGLVNIIEEKETEDVPDDLDGAPIEEELDGAPLEDVDGIPIDATPIDDLDGVPIKSLDDDLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPIKEEMTESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDVSKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNKH", "length": 1029 }, "evidence": [ { "id": "RGD:1307882", "url": "https://alliancegenome.org/gene/RGD:1307882#orthology", "database": "AGR" }, { "id": "MGI:1915208", "url": "https://alliancegenome.org/gene/MGI:1915208#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070410-141", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070410-141#orthology", "database": "AGR" }, { "id": "HGNC:30855", "url": "https://alliancegenome.org/gene/HGNC:30855#orthology", "database": "AGR" }, { "id": "FB:FBgn0034572", "url": "https://alliancegenome.org/gene/FB:FBgn0034572#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6NV83-1", "protein_name": "U2 snRNP-associated SURP motif-containing protein", "gene_name": "U2surp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADKTPGGSQKASSKNRSSDVHSSGSSDAHMDASGPSDSDMPSRTRPKSPRKHNYRNESSRESLCDSPHQNLSRPLLENKLKAFSIGKMSTAKRTLSKKEQEELKKKEDEKAAAEIYEEFLAAFEGSDGNKVKTFVRGGVVNAAKDEHETDEKRGKIYKPSSRFADQKNPPNQSSNERPPSLLVIETKKPPLKKGEKEKKKSNLELFKEELKQIQEERDERHKTKGRLSRFEPPQSDSDGQRRSMDVPSRRNRSSGVLDDYAPGSHDVGDPSTTNLYLGNINPQMNEEMLCQEFGRFGPLASVKIMWPRTDEERARERNCGFVAFMNRRDAERALKNLNGKMIMSFEMKLGWGKAVPIPPHPIYIPPSMMEHTLPPPPSGLPFNAQPRERLKNPNAPMLPPPKNKEDFEKTLSQAIVKVVIPTERNLLALIHRMIEFVVREGPMFEAMIMNREINNPMFRFLFENQTPAHVYYRWKLYSILQGDSPTKWRTEDFRMFKNGSFWRPPPLNPYLHGMSEEQETEAFVEEPSKKGALKEEQRDKLEEILRGLTPRKNDIGDAMVFCLNNAEAAEEIVDCITESLSILKTPLPKKIARLYLVSDVLYNSSAKVANASYYRKFFETKLCQIFSDLNATYRTIQGHLQSENFKQRVMTCFRAWEDWAIYPEPFLIKLQNIFLGLVNIIEEKETEDVPDDLDGAPIEEELDGAPLEDVDGIPIDATPIDDLDGVPIKSLDDDLDGVPLDATEDSKKNEPIFKVAPSKWEAVDESELEAQAVTTSKWELFDQHEESEEEENQNQEEESEDEEDTQSSKSEEHHLYSNPVREEATESKFSKYSEMSEEKRAKLREIELKVMKFQDELESGKRPKKPGQSFQEQVEHYRDKLLQREKEKELERERERDKKDKEKLESRSKDKKEKDECTPTRKERKRRHSTSPSPSRSSSGRRVKSPSPKSERSERSERSHKESSRSRSSHKDSPRDASKKAKRSPSGSRTPKRSRRSRSRSPKKSGKKSRSQSRSPHRSHKKSKKNKH", "length": 1029 }, "evidence": [ { "id": "RGD:1307882", "url": "https://alliancegenome.org/gene/RGD:1307882#orthology", "database": "AGR" }, { "id": "MGI:1915208", "url": "https://alliancegenome.org/gene/MGI:1915208#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070410-141", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070410-141#orthology", "database": "AGR" }, { "id": "HGNC:30855", "url": "https://alliancegenome.org/gene/HGNC:30855#orthology", "database": "AGR" }, { "id": "FB:FBgn0034572", "url": "https://alliancegenome.org/gene/FB:FBgn0034572#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W2N6-1", "protein_name": "U2 snRNP-associated SURP motif-containing protein", "gene_name": "cg9346", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSKQGNKSKDSAAASATLKRISEKKLEAFTVGTFSKRQLSKKELEDQKKKEDAAAAAHAFKEFVETFQDAPTPSSKVWVKAGTYDAGSRREDKSEKGKLYKPVSKLMEKSSSDKVEDYAKTLASDLKKDSGPLKKKNQEKKKSNLELFKEELRQIQEEREERHKYKHMASSHSAPAQQPAASAAPVPSSSVSTTSQNSSSSKESGSFDTGDPNTTNLYLGNLNPKISEQQLMEIFGRYGPLASIKIMWPRSEEEKQRGRNCGFVAYMSRKDAERALKTLNGRYIMGYEMRLGWGKTVPIMNTPIFTPQALLEMTLPPPPSGLPFNAQPPPSEADVLPKKNYKEFNQEDKENMERILAKCVVKVHIPTEKAVLNVIHRMIEFVIREGPMFEALIMIREMENPLFAFLFDNESPAHIYYRWKLFSLLQGDTPNEWREEEFRMFKNGPVWKPPIANFYTQGMPDELVVDPDAPVVHKGALSNAQRNRLEDLIRHLTPERARIGDAMIFCIEHADAADEICECIAESLSNINTLASKKIARLYLISDILHNCTVKVANASFFRKSVEKQLLDIFDNLHNYYLNIESRLKAEGFKSRVCNVIRTWEEWTIYPKDFMAQLTAKFLGKPYVKPVNNSPQAEETRFDEALDEDIDGAPLSGEEKDDEDLDGVPLDGAALLKSALKRAIPDADAGTPKRDTPKKDEYLDEIDGIPLDDDLDGVPLEKETKSTAKLPGFIPSKWETVDPQQVEAQAITTSKWDTLDPPDPPKFFSSDDDSGEDNPQKYTDEMRQKLRDIESKAIQYQDELESGKRRLEPGWSVPEQVEQFRKRLLKQDSRSEATVDSPLSYMHIKSKSSKVSESPALFRSSSRKRSHSPFSGGESKRRDYSPETSRSSKSSKRNRSRSPSSSPKRYTERSSRSSRYETPASGSSRSRSSPTSSRSSRREEPSPPRHRSDKHKHKHRH", "length": 957 }, "evidence": [ { "id": "RGD:1307882", "url": "https://alliancegenome.org/gene/RGD:1307882#orthology", "database": "AGR" }, { "id": "MGI:1915208", "url": "https://alliancegenome.org/gene/MGI:1915208#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070410-141", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070410-141#orthology", "database": "AGR" }, { "id": "HGNC:30855", "url": "https://alliancegenome.org/gene/HGNC:30855#orthology", "database": "AGR" }, { "id": "FB:FBgn0034572", "url": "https://alliancegenome.org/gene/FB:FBgn0034572#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "A5PN19", "url": "https://www.uniprot.org/uniprotkb/A5PN19" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A5PN19", "url": "https://www.uniprot.org/uniprotkb/A5PN19" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "RNA processing", "id": "GO:0006396", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006396", "evidence": [ { "database": "UniProtKB", "id": "A5PN19", "url": "https://www.uniprot.org/uniprotkb/A5PN19" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 355, "end_pos": 357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" }, { "start_pos": 675, "end_pos": 677, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5PN19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PN19" }, { "id": "PS51391", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51391" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CID", "eco_id": "ECO_0000259", "start_pos": 425, "end_pos": 570, "start_aa": "Leu", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "A5PN19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PN19" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 166, "end_pos": 247, "start_aa": "Thr", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "A5PN19", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5PN19" }, { "id": "PS50128", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50128" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SURP motif", "eco_id": "ECO_0000259", "start_pos": 320, "end_pos": 363, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 164, "end_pos": 166 }, { "start_pos": 355, "end_pos": 357 }, { "start_pos": 502, "end_pos": 504 }, { "start_pos": 60, "end_pos": 62 }, { "start_pos": 675, "end_pos": 677 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5WUG5-1", "uniprot_ac": "A5WUG5", "uniprot_id": "A5WUG5_DANRE", "mass": { "chemical_mass": 41903.0, "monoisotopic_mass": 41903.0 }, "refseq": { "ac": "NP_001093462", "name": "uncharacterized protein LOC558654 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093462" }, "gene_names": [ { "name": "si:ch211-225k7.6", "type": "recommended", "evidence": [ { "id": "A5WUG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUG5" } ] }, { "name": "si:ch211-225k7.6", "type": "synonym", "evidence": [ { "id": "NP_001093462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093462" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC558654 precursor", "type": "synonym", "evidence": [ { "id": "A5WUG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUG5/entry#names_and_taxonomy" } ] }, { "name": "lectin C-type domain containing protein", "type": "synonym", "evidence": [ { "id": "NP_001093462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093462" } ] }, { "name": "uncharacterized protein LOC558654 precursor", "type": "synonym", "evidence": [ { "id": "NP_001093462", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093462" } ] } ], "function": [ { "annotation": "PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000007.1. On Mar 6, 2008 this sequence version replaced XP_686732.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001093462", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093462" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUG5", "url": "https://www.uniprot.org/uniprotkb/A5WUG5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-225k7.6", "url": "https://www.uniprot.org/uniprotkb/A5WUG5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-121", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-121", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000075036", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000075036", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "558654", "url": "https://www.ncbi.nlm.nih.gov/gene/558654", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558654", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558654", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NTENCAF", "url": "https://omabrowser.org/oma/group/NTENCAF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5WUG5", "url": "https://www.orthodb.org/?gene=A5WUG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45784:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45784:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001093462", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093462", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5WUG5", "url": "https://www.uniprot.org/uniprotkb/A5WUG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WUG5-1", "url": "https://www.uniprot.org/uniprotkb/A5WUG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-121", "url": "https://zfin.org/ZDB-GENE-070705-121", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAQTLYFPLLLIALCSISECVQRQYHFINENKTWTEAQRYCREKYTDLATVDNMNDTIQLNKSVNDVRLWIGLQRKWQWSSGDPELFLNWESGQPDGKDECAFMRHGKWHDGKCSDTWFVICYNMSRGLVFVNQTMNWRAAQSYCRQNHIDLVSVRNQNESQQLEKFINDSIPSRSDVWIGLFRDWQWSDQSNYSFSYWNTNEPNNYGNNENCTVLKENTNGHWADISCDCQFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYKVMNVVKLASTGAVWLGLRHSCALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRSGAVQSGGDQTWISRPETDRLNFICRNY", "length": 359, "header": "tr|A5WUG5-1|A5WUG5_DANRE Isoform 1 of Uncharacterized protein LOC558654 precursor OS=Danio rerio OX=7955 GN=si:ch211-225k7.6 PE=4 SV=1 CANONICAL=A5WUG5-1" }, "isoforms": [ { "isoform_ac": "A5WUG5-1", "url": "https://www.uniprot.org/uniprotkb/A5WUG5/entry#A5WUG5-1", "sequence": { "sequence": "MAQTLYFPLLLIALCSISECVQRQYHFINENKTWTEAQRYCREKYTDLATVDNMNDTIQLNKSVNDVRLWIGLQRKWQWSSGDPELFLNWESGQPDGKDECAFMRHGKWHDGKCSDTWFVICYNMSRGLVFVNQTMNWRAAQSYCRQNHIDLVSVRNQNESQQLEKFINDSIPSRSDVWIGLFRDWQWSDQSNYSFSYWNTNEPNNYGNNENCTVLKENTNGHWADISCDCQFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYKVMNVVKLASTGAVWLGLRHSCALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRSGAVQSGGDQTWISRPETDRLNFICRNY", "length": 359, "header": "tr|A5WUG5-1|A5WUG5_DANRE Isoform 1 of Uncharacterized protein LOC558654 precursor OS=Danio rerio OX=7955 GN=si:ch211-225k7.6 PE=4 SV=1 CANONICAL=A5WUG5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "A5WUG5", "url": "https://www.uniprot.org/uniprotkb/A5WUG5" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] } ], "pathway": [ { "id": "dre:558654", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558654", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1N7C8-1", "protein_name": "CLECT_1 and CLECT domain-containing protein isoform X1", "gene_name": "si:ch211-282j17.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYSSLLLIALCSISECVQHQYYYINVNKTWTEAQRYCREKYTDLATIDNMNELNNMNKLVKSENNGATEYVWTGLQRMSVYKWHWSSGDPALLLNWASGQPAGSDDCAVMRNGQWFDEPCSKTWIFICYNTNTGLVFVDQLMNWRAAQSYCRQNHIDLVSVRNQNESQQLEKFINDRNSSGSAVWIGLFRDTWQWSDQSNSSFRYWNTAEPNNAGGIQNCIGMNQNAQGRWHDISCTGSFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHNYCSMNMWLWVNGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHRLNFICTNY", "length": 370 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1NE49-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-83f18.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQSLFFPLLLIALCSISECVQRQYHFINENKNWTEAQRYCREKYTDLATVDNMNDMIQLNKSVNNVNNQNIYIGLQKTNVSKWHWSSGDLVLFLNWASGEPNNSYNCGTIKNGQWFAESCNNTCFFICYNMSRGLVFVNQNMNWTVAQSYCRQNHIDLVTVRNQNESQQLEKFINDRNSSGSAVWIGLFRDTWQWSDQSNSSFRYWAANFKDSSYSAAIQPNISGQWADYSSNYNQFPFVCHEDKLIVIQQTKSWSEALRYCRQNHVDLVSVQSVEMQYEVMNVVKLASTEAVWLGLRHSCALGIWFWVSGQTVCYQYWAPGNGTSEEDCEPTVRSGAVQSGGDQTWISRPEIDKLNFICRNY", "length": 364 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1P3G7-1", "protein_name": "Uncharacterized protein LOC555551 isoform 1 precursor", "gene_name": "si:dkey-88n24.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQSLYFPLHLIALCSISECVQRQYHFINENKNWTEAQRYCREKYTDLATVDNMNDLIQLKKSANNEGVQNIWIGLQRTGVYKWYWSSGDPALFLNWASGEPAGSEECAVMRNGQWIVWLCSNVSFFICNNTSTGLVFVNQSMTWREAQSYCRQNHIDLVSVRNQNENQQLEKFINDRNSSGSAVWIGLFRDTWQWLDQSNSSFRYWYPGEPNNYGGHEDCAVIGKNTQRGWADVPCDSRQIPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHHYCSMNMWLWVSGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGNQTWISLPESHRLNFICTNY", "length": 368 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RF17-1", "protein_name": "C-type mannose receptor 2", "gene_name": "si:ch211-225k7.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQSLYFPLLLIALCSISECVQRQYHFINEKKTWTEAQRYCREKYTDLATVDNMNDTTELMKSVYDVRLWIGLQRKWQWSSGGPALFLNWGYNQPDGSDECAFMKNGVWHDGKCSDTWIFVCYNMSRGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNENQQLENFINDRNSSGSAVWIGLFRDSWQWSDQSTYSFSYWNNQEPNNVGGNENCTVLMENTQGHWADISCDRQFPFVCHEDKLIVIQQNLSWSEALRYCRQHHVDLVSVQSVEMQYEVMNVVKLASTEAVWLGLRFSHILGIWFWVSGETVYYRNWAPGNGTSEEDCEPTVRSGAVQSGGNQTWISRPETDKLNFICSRYE", "length": 361 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YZA0-1", "protein_name": "C-type mannose receptor 2", "gene_name": "si:ch211-282j17.7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQALFFLQLVALCSVSECVQHQYYFINQVKNWTEAQRYCRENYTDLATADNMNDTIELIKPVNKARAQNIWIGLRKTSVYTWHWSSGDTVLFLNWASGQPASSNNCTVMRNGHWFDWSCSATCFFICYNTNSGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNESQQLEKFINDRNSSGSAVWIGLFRDTWQWSDHSNSSFRYWNTAEPNNYGGDENCSVIETNAQRGWADNPCHYQFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHNYCSMNMWLWVNGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHTLNFICTNY", "length": 366 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9Q208-1", "protein_name": "Macrophage mannose receptor 1", "gene_name": "si:ch211-225k7.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYFPLLLIALCSISECVQRQYHFIHEKKTWTEAQRYCREKYTDLATVDNMNDTIQLMKSVNDERIWIGLQRKWQWSSGDPALFLNWAYRQPDGKDECAFMINGEWHDGACSNTLFFICYNMSRGLVFVDQMMNWRDAQSYCRQNHTDLVTVRNQNESQQLEKFINDSNSSGSAVWIGLFRDWQWSDQSNYSFRYWDTNQPDNQGGTENCAVITQNVQGRWNDISCDHQFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLRFSHILGIWYWVSGETVFYQNWAPGNGTSEEDCEPTVRSGAVQSGGSQTWISRPETDRLNFICSRYG", "length": 360 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TYY6-1", "protein_name": "C-type mannose receptor 2", "gene_name": "si:dkey-192d15.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSQAQYILLLIALCSISECVQRQYHFINEKKNLTEAQRYCRENYTDLATVDNMNNMIQLNKSVNDERVWIGLQRTSVYKWHWSSGDPALFLNWASGQPVGSDNCTYMTNGQWIVGPCSAISPFICYNMSRGLVFVNQTVNWRAAQSYCRQNHTDLVIVRNQNESQQLEQFINDRQLSGGAIWIGLFRDPWQWSDQSNSSFRYWKTTEPDNYGGIENCTVIEENAQGRWADYPCYWKMPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHHYCSMNMWLWLTGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHRLNFICTN", "length": 362 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LXV6-1", "protein_name": "C-type lectin domain containing 20A", "gene_name": "Clec20a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWYCQEHYTDLADLQSMNSLVSVMVVYSYTSSVQAWIGLFYDVRISGLSWSSGSVFTMPTWSKLPVFQDGVCATLYSWYGVPALGAASCTGQKPFICYFDPAVGHRISLVSPLKDLTTLPEEAEVKIGGQTFIRIKQTMTWLSALTYCRHHYTDLADLQRVTDKDKDSLKPVINGDDAWIGLYFSVKINHLTWSSDQGSSIPEWLQEMPMFGQGLCAGIRTFANHPPQIYALLCPDLKPFICFNDPSIGHRQSAEMPSLIDTSSPRVTQHSKVPTRTTSRPNTGTSTDSTDASQVLDSASWIPRQVSHEPTAVSSGTCGFRTCDTTTPASTTVGLTALQSQGMVSIRPVATSAYPGETKERTTEASVSGSTAEVQGNWTSVPAAWNPDTSTGTAGSLPGTTTAMTTVEGGIYKGDTTSATEAQHLCSPKYPESKKKAAASESEHSFGILKADFAIPALRDPEEMKDQLLSEIQEVLKLILGHEEFTLKWIGSEVNKK", "length": 497 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AC58G2Y2-1", "protein_name": "C-type mannose receptor 2-like isoform X1", "gene_name": "si:dkey-28d5.15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDKHSEAFSLKQISEMAQKLQFFLLLIALCSISECVQRQYHFINEMKTWTEAQRYCREKYTDLATVDSMNDTTELMKIVNNVRLWIGLERKWQWSSGDPVLFLNWGDKQPDGKDECAFMRNGEWHDWPCNKDCFFVCYNRSRGLVFVNERKNWTDAQSHCRLHYTDLVSVRNQNENQQLEKFINDSPKPEPGSDVWIGLFRDSWQWSDQSNYSFSNWKLGEPNNVGDHENCTAVEKDAQGQWIDISCDHQLPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYEVMSDVKKASTEAVWLGLRFSHILGIWFWVSGETVCYQNWAPGNGTSEENCEATVRSGAVQSGGDQTWISRPETHKLNFICSKY", "length": 377 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58H6E4-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkeyp-94g1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKSKKEKSSTVSQWVAQSPHSKKVTGSSPSRRGSGVMHESLFMLLLLSGLLRMNSELYRDYYFINIRMSWPEAQSYCRAKYTDLATAESTDDVNRLLNSVGAQYNGSVWIGLKRGTQKRWGWSYGDNTIAQYTAWSNGEPSSTNECGFLAYGNWRTYNCSDLIYFACYNGTGYTMLTMWMNWTDAQSYCRKHYIDLPTIHNSTELAQINSAVSYNAWLWIGLFKDSWEWSDKWGWFFRYWAVGQPSPSAGSSDCVGMSTTNFGKWASYSCGLQQPFICYGGTKFPYIYQYVNKSMTWPDAQSYCRARFTDLATVDTMDDVNRLVNIVDPGFSGSVWIGLQNGGQNRWIWSLGNGVLSTYSFWNPGEPSGDGDCGSSTYGNWSDESCSTVLPFLCFDDHTGFAIINTAMTWRDAQSYCRHYHTDLATIDSVDQQHMISTQSTLWIGLFLDSWGWSDQDILSFRYWAPDQPPLSSVSGDCAGLSTADFGQWAQYSCNLQQNFICYGDDSLINKQIVHIKLSCKDKCTPNDPTLQTAFLNKINEKLRSLGLERKSKISWKQSEDEEVFHEETYPPTNY", "length": 575 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A5WUJ5-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-83f18.11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGQFLDSLLLLVALCSISECVQRQYHFINEMKTWTEAQRYCREKYTDLATVDNMNDMIQLMKSVKVNDRGVWIGLQRKWQWSSGDPALFLHWGNEQPDGADECAFMRNGQWEDGKCNDSWIFVCYNMSRGLVFVNQAMTWRAAQSYCRQNHTDLVSVRNQNESQQLEKFINDSHKFASEVWIGLFRDSWQWSDRSNYSFSYWNNQEPNDYGGKENCTVVQPKTEGRWNDIVCNNLFPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYKVMNVVKLASTEAVWLGLRHSCALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRSGAVQSGGSQTWISRPETHKLNFICRNY", "length": 362 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F6PDD5-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-81n2.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYIPLLLIALCSISECVQRQYHFINEGRNQTEAQKYCREKYTDLATVDNMSDMNQLIKSVNNGGVENIWIGLQRTSVYKWHWSSGDPVLFLNWTSGEPAGSNECTVMHNGQWINEACSNTRFFICYNMSTGLVFVDQMMNWRDAQSYCRQNHTDLVSVRNQNENQQLEKFINDRNSSGAEVWIGLFRDSWQWSDQSNSSFRYWNTGEPNNVEESCAVIGKNPQRGWADVLCDGRKIPFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQYKVMNVVKLASTEAVWLGLRHSCALGIWFWVSGQTVCYQNWAPGNGTSEEDCEPTVRSGAVQSGGNQTWISRPETDRLNFICRNY", "length": 366 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q1L8A7-1", "protein_name": "Uncharacterized protein LOC555932 precursor", "gene_name": "si:ch73-335d12.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQTLYLSLLLIALCSISECVQRQYHFINKNKTWTEAQRYCREKYTDLATVDNMNDMIQMNKSVKVNDGYAWIGLQRTSVYKWHWSSGDSVLFLNWASGQPAGGDNCTVMRNGKWFVEPCSDAWTFICYNMSRGLVFVNQTMNWRDAQSYCRQNHIDLVSVRNQNENQQLEKFINDRNSSGSAVWIGLFRDTWQWSDQSNSSFRYWDTIEPNNAGGHENCAVIYLYNLKQWNDILCDRQYAFVCHEDKLIVIQQNLSWSEALRYCRQNHVDLVSVQSVEMQRRVMNVVKLASTEAVWLGLHNFCSMNMWLWLSGDMVCYQNWAPGNGSTPENCKLENRKGAVQSGGDQTWISLPESHRLNFICTNY", "length": 366 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZU45-1", "protein_name": "Putative C-type lectin domain family 20 member A", "gene_name": "CLEC20A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPRALLLSFCAAALQLVSSKRDLVLVKEALSWYDAQQHCRLHYTDLADLQPSGLWKLYSLMTSTPAWIGLFFDASTSGLRWSSGSTFTALEWGQKLPEFGVGFCATLYTWLKLPSIGAASCTAQKPFLCYCDPDVGHLISTKPSLSLTTSPKPAVVQISGQTFMRFDQVMTWSSALLYCRSHHTDLADLQMVTDETGKEALRSIMSETEAWIGLYLNANSGSLSWSSDLGASIPSWLQVPMMVRGLCTALGIYMTYSPKVYSVNCSSLLPFFCFYDSSTGHRASAELPPLFHTSPTEMTEETTPRPGRAVASVGSGTDRRDTAAATEAQHLSSESKEKTSAQKSGHPFGILKADFTISTLMDPEEMKDQFLRQIQEVLKLTLGHEQFRLKWVSFEVNKK", "length": 400 }, "evidence": [ { "id": "HGNC:34521", "url": "https://alliancegenome.org/gene/HGNC:34521#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-121", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-121#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 133, "end_pos": 135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 169, "end_pos": 171, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 212, "end_pos": 214, "annotation": "n_glycosylation_sequon" }, { "start_pos": 248, "end_pos": 250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 319, "end_pos": 321, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 55, "end_pos": 57, "annotation": "n_glycosylation_sequon" }, { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5WUG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUG5" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 25, "end_pos": 123, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 133, "end_pos": 135 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 169, "end_pos": 171 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 212, "end_pos": 214 }, { "start_pos": 248, "end_pos": 250 }, { "start_pos": 319, "end_pos": 321 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 55, "end_pos": 57 }, { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5WUG7-1", "uniprot_ac": "A5WUG7", "uniprot_id": "A5WUG7_DANRE", "mass": { "chemical_mass": 41984.0, "monoisotopic_mass": 41984.0 }, "refseq": { "ac": "NP_001093539", "name": "uncharacterized protein LOC100000851 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093539" }, "gene_names": [ { "name": "si:dkey-83f18.2", "type": "recommended", "evidence": [ { "id": "A5WUG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUG7" } ] }, { "name": "si:dkey-83f18.2", "type": "synonym", "evidence": [ { "id": "NP_001093539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093539" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100000851 precursor", "type": "synonym", "evidence": [ { "id": "A5WUG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUG7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100000851 precursor", "type": "synonym", "evidence": [ { "id": "NP_001093539", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093539" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588728.8148986.1 [ECO:0000332] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000007.1. On Jul 26, 2007 this sequence version replaced XP_001337028.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001093539", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093539" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUG7", "url": "https://www.uniprot.org/uniprotkb/A5WUG7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-83f18.2", "url": "https://www.uniprot.org/uniprotkb/A5WUG7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-501", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-501", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000055346", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000055346", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00037", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00037", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd03602", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03602", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100000851", "url": "https://www.ncbi.nlm.nih.gov/gene/100000851", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018378", "database": 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"table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5WUM7-1", "uniprot_ac": "A5WUM7", "uniprot_id": "A5WUM7_DANRE", "mass": { "chemical_mass": 28226.0, "monoisotopic_mass": 28226.0 }, "refseq": { "ac": "NP_001093518", "name": "dehydrogenase/reductase SDR family member 11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093518" }, "gene_names": [ { "name": "dhrs11a", "type": "recommended", "evidence": [ { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7" } ] }, { "name": "dhrs11a", "type": "synonym", "evidence": [ { "id": "NP_001093518", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093518" } ] }, { "name": "zgc:153028", "type": "synonym", "evidence": [ { "id": "NP_001093518", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093518" }, { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7" } ] } ], "protein_names": [ { "name": "Dehydrogenase/reductase SDR family member 11", "type": "recommended", "evidence": [ { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.270", "type": "synonym", "evidence": [ { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7/entry#names_and_taxonomy" } ] }, { "name": "1.1.1.62", "type": "synonym", "evidence": [ { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7/entry#names_and_taxonomy" } ] }, { "name": "17-beta-hydroxysteroid dehydrogenase", "type": "synonym", "evidence": [ { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7/entry#names_and_taxonomy" } ] }, { "name": "3-beta-hydroxysteroid 3-dehydrogenase", "type": "synonym", "evidence": [ { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7/entry#names_and_taxonomy" } ] }, { "name": "Estradiol 17-beta-dehydrogenase", "type": "synonym", "evidence": [ { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7/entry#names_and_taxonomy" } ] }, { "name": "Short-chain dehydrogenase/reductase family 24C member 1", "type": "synonym", "evidence": [ { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7/entry#names_and_taxonomy" } ] }, { "name": "dehydrogenase/reductase (SDR family) member 11a", "type": "synonym", "evidence": [ { "id": "NP_001093518", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093518" } ] }, { "name": "dehydrogenase/reductase SDR family member 11", "type": "synonym", "evidence": [ { "id": "NP_001093518", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093518" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC124218.1, GFIL01008584.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA4476730 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On or before Apr 18, 2008 this sequence version replaced NP_001070071.1, XP_001331317.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001093518", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093518" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUM7", "url": "https://www.uniprot.org/uniprotkb/A5WUM7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dhrs11a", "url": "https://www.uniprot.org/uniprotkb/A5WUM7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060929-324", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-324", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000046090", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000046090", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05343", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05343", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "791578", "url": "https://www.ncbi.nlm.nih.gov/gene/791578", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:791578", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:791578", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WRWMWET", "url": "https://omabrowser.org/oma/group/WRWMWET/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5WUM7", "url": "https://www.orthodb.org/?gene=A5WUM7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43115", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43115", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43115:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43115:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001093518", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093518", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "24616", "url": "https://www.rhea-db.org/rhea/24616", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "34787", "url": "https://www.rhea-db.org/rhea/34787", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A5WUM7", "url": "https://www.uniprot.org/uniprotkb/A5WUM7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WUM7-1", "url": "https://www.uniprot.org/uniprotkb/A5WUM7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060929-324", "url": "https://zfin.org/ZDB-GENE-060929-324", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MIMMERWKGRVALVTGASVGIGAAVARALVQHGMKVVGCARNVDKIEKLAAECQSAGYSGILIPYKCDLCNEEEILSMFSAIKTLHQGVDVCINNAGLAHNEPLLSGRTDGWRNMIDVNILALAICTREAYQSMRERHVDDGHIININSMGGHRMVSSADEHFYCATKYAVTAMTEGLRQELREAKTHIRATCISPGIVETEFAFRHHNSDPERAAAVYESIKCLKAEDIASAVTYVLSAPAHVQIGDVQMRPVDQVS", "length": 258, "header": "tr|A5WUM7-1|A5WUM7_DANRE Isoform 1 of Dehydrogenase/reductase SDR family member 11 OS=Danio rerio OX=7955 GN=dhrs11a PE=3 SV=1 CANONICAL=A5WUM7-1" }, "isoforms": [ { "isoform_ac": "A5WUM7-1", "url": "https://www.uniprot.org/uniprotkb/A5WUM7/entry#A5WUM7-1", "sequence": { "sequence": "MIMMERWKGRVALVTGASVGIGAAVARALVQHGMKVVGCARNVDKIEKLAAECQSAGYSGILIPYKCDLCNEEEILSMFSAIKTLHQGVDVCINNAGLAHNEPLLSGRTDGWRNMIDVNILALAICTREAYQSMRERHVDDGHIININSMGGHRMVSSADEHFYCATKYAVTAMTEGLRQELREAKTHIRATCISPGIVETEFAFRHHNSDPERAAAVYESIKCLKAEDIASAVTYVLSAPAHVQIGDVQMRPVDQVS", "length": 258, "header": "tr|A5WUM7-1|A5WUM7_DANRE Isoform 1 of Dehydrogenase/reductase SDR family member 11 OS=Danio rerio OX=7955 GN=dhrs11a PE=3 SV=1 CANONICAL=A5WUM7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A5WUM7", "url": "https://www.uniprot.org/uniprotkb/A5WUM7" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A5WUM7", "url": "https://www.uniprot.org/uniprotkb/A5WUM7" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:791578", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:791578", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1QDB3-1", "protein_name": "Dehydrogenase/reductase SDR family member 11", "gene_name": "dhrs11b.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDRWRGRVVLVTGASVGIGAAIAKSLVQHGMKVVGCARNVEQIKKLAAECVSSGYSGALFPYKCDLSVEDEVLSMFSWIKAQHKGVDVCINNAGLALPEPLLSGKTSSWRTMMDVNVMALAVCTREAYQSMKERKVDDGHIININSICGHRVLNYADGHFYTATKYAVTALTEGLRQELREAKTHIRATGISPGIVKTEFAYRLFSDDQEKAAAMYNSGECLQADDITNAVVYVLSAPPHVQIGDIELTPVDQSM", "length": 255 }, "evidence": [ { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1R5X7-1", "protein_name": "Dehydrogenase/reductase SDR family member 11", "gene_name": "dhrs11b.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDRWKGRVALVTGASVGIGAAIAKALVQHGMKVVGCARNVEQIEKLAAECVSGGYSGALFPYKCDLSVEDEVLSMFSWIKAQHKGVDVCINNAGLALPEPLLNGKASGWRTMMNVNVIGLSLCTREAFQSMKERNIDDGHIININSMSGHRVVNSAYTHFYTATKYAVTALTEGLRQELREAKTHIRATSISPGLVETEFAYRLFSENQDKASATYKSIKCLQPDDLANAVVYVLSAPPHVQIGDIQMRPVEQLT", "length": 255 }, "evidence": [ { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3V978-1", "protein_name": "Dehydrogenase/reductase SDR family member 11", "gene_name": "Dhrs11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWPSVEVPRAEPRPEAGPQGVGSRRSSNISKLPAPAPAVTRELPSFSNSRLNSAIPVPSSPNEVGRRLGTMTRAGMERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAVRSQHSGVDICINNAGMARPDSLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMCGHRVPPQSVIHFYSATKYAVTALTEGLRQELLEAQTHIRATCISPGLVETQFAFKLYDKDPREAAATYEHIKCLRPEDVAEAVIYVLSTPPHVQVGDIQMRPTEQVT", "length": 330 }, "evidence": [ { "id": "MGI:2652816", "url": "https://alliancegenome.org/gene/MGI:2652816#orthology", "database": "AGR" }, { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" }, { "id": "A5WUM7", "url": "https://omabrowser.org/oma/group/A5WUM7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q05016-1", "protein_name": "NADP-dependent 3-hydroxy acid dehydrogenase", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSQGRKAAERLAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVHVAQLDITQAEKIKPFIENLPQEFKDIDILVNNAGKALGSDRVGQIATEDIQDVFDTNVTALINITQAVLPIFQAKNSGDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSLRKELINTKIRVILIAPGLVETEFSLVRYRGNEEQAKNVYKDTTPLMADDVADLIVYATSRKQNTVIADTLIFPTNQASPHHIFRG", "length": 267 }, "evidence": [ { "id": "MGI:2652816", "url": "https://alliancegenome.org/gene/MGI:2652816#orthology", "database": "AGR" }, { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" }, { "id": "A5WUM7", "url": "https://omabrowser.org/oma/group/A5WUM7/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3U0B3-1", "protein_name": "Dehydrogenase/reductase SDR family member 11", "gene_name": "Dhrs11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRAGMERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAVRSQHSGVDICINNAGMARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNIDDGHIININSMCGHRVPPQSVIHFYSATKYAVTALTEGLRQELLEAQTHIRATCISPGLVETQFAFKLHDKDPGEAAATYEHIKCLRPEDVAEAVIYVLSTPPHVQVGDIQMRPTEQVT", "length": 260 }, "evidence": [ { "id": "MGI:2652816", "url": "https://alliancegenome.org/gene/MGI:2652816#orthology", "database": "AGR" }, { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-324", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-324#orthology", "database": "AGR" }, { "id": "A5WUM7", "url": "https://omabrowser.org/oma/group/A5WUM7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5LJT3-1", "protein_name": "Uncharacterized protein", "gene_name": "CG12466", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MERWHDRVAVVTGASSGIGAAVARHLVSAGVIVVGLARRVDRMKAIKEQLPPELQGRLHAIHCDVEDLDSVTAAFDWIEEQLGGCDILVNNAGCLNPGQLLTLELEQLQQVLNVNLMGVVICTRRAFRSMQQREVDGHVILINSLTGRNIINPPGDELQVLNMYPLTKHGVTAMLEVLRQELRGFKTKIKVTSITPGVTDTEILPSGYGILPMLKPDDIAAGIMYVLGTPAHVQVHELTIKPLGEPF", "length": 247 }, "evidence": [ { "id": "MGI:2652816", "url": "https://alliancegenome.org/gene/MGI:2652816#orthology", "database": "AGR" }, { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q6UWP2-1", "protein_name": "Dehydrogenase/reductase SDR family member 11", "gene_name": "DHRS11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARPGMERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKLHDKDPEKAAATYEQMKCLKPEDVAEAVIYVLSTPAHIQIGDIQMRPTEQVT", "length": 260 }, "evidence": [ { "id": "MGI:2652816", "url": "https://alliancegenome.org/gene/MGI:2652816#orthology", "database": "AGR" }, { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-324", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-324#orthology", "database": "AGR" }, { "id": "A5WUM7", "url": "https://omabrowser.org/oma/group/A5WUM7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q71R50-1", "protein_name": "Dehydrogenase/reductase SDR family member 11", "gene_name": "DHRS11", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERWTGRVALVTGASVGIGAAVARALVQHGMKVVGCARSVDKIEKLAAECQSAGYPGTLIPYKCDLSNEEEILSMFSAIKTLHQGVDVCINNAGLARPEPLLSGKTEGWRTMIDVNVMAVSICTREAYQSMKERNIDDGHIININSMNGHSVVPQSVVHFYSATKYAVTALTEGLRQELREAKTHIRATCISPGLVETGFAFKLHDNDPERAAATYESIRCLKAEDMANAVIYVLSAPPHVQIGDIQMRPTEQIS", "length": 255 }, "evidence": [ { "id": "A5WUM7", "url": "https://omabrowser.org/oma/group/A5WUM7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8IRN0-1", "protein_name": "Farnesol dehydrogenase", "gene_name": "CG7090", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDRWQNRVAVISGASSGIGAACARLLVAAGLQVVGLARRTDRLEQLRQSLPAEQRMRFHQHKCDVSQELQVDTAFEWIEKELGGIDVLINNAGIVLGGQLIDMPTKDINNILQTNLMGSIYCTKLAASSMRRRQVAGHLIFVNSTAGVAGYKPDPADESLNAYTPSKFALTAVQEICRQELINQGSKIKTTSINPGWVATEIVPDETKAKLGEVILQADDVAQAVLYALSTPPHTQVEQITLRAVGEYF", "length": 249 }, "evidence": [ { "id": "MGI:2652816", "url": "https://alliancegenome.org/gene/MGI:2652816#orthology", "database": "AGR" }, { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VD30-1", "protein_name": "1.1.1.105", "gene_name": "rdhB", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MENNFYWRNKVAVVTGASVGIGATTAIELANAGMVVVGLARRVELIEALRDQVTGVGKIFARQCDLNDEEQLASAFNWIREKFQAIHVLICNAGILKANFLSESPTKDIKELFDTNVVATASCLREALKHMAAVKVRGHIVVMNSVLGHRIPEVPVPLFSVYPATKHAITALCQTVRQEIHFLKLNIKLTSICPGMVDTDFLSVYSQAVAELPKLQARDVAKAVLYALNTPDGVQVEDIILQQMRKVD", "length": 248 }, "evidence": [ { "id": "MGI:2652816", "url": "https://alliancegenome.org/gene/MGI:2652816#orthology", "database": "AGR" }, { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VDC0-1", "protein_name": "Uncharacterized protein", "gene_name": "FOHSDR", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNRWLNRVAVVTGASAGIGAACCRDLVAKGMVVVGLARREKVLQDIKSSLPADQAARFHTRPCDVSNEQQVIDTFAWIDRTLGGADVLVNNAGIIRQMNITDPENSADVRAILDVNVLGVTWCTRQWFLSLQRRKVNDGHVVVINSVVGHSVPAVEGFSLNMYAPSKHAITALTEILRQEFIKKGTQTKITSISPGVVATEIFEAGSWEQPTGMPMLRSEDIADAVTYCIQTPPTVQIKELIIKPVGEGF", "length": 250 }, "evidence": [ { "id": "MGI:2652816", "url": "https://alliancegenome.org/gene/MGI:2652816#orthology", "database": "AGR" }, { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VMH9-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG9150", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MERWQNKLAVVTGASGGIGAACARAMIGAGLRVVGLARREAKLKELRESLPRELQANFIPRRCDVSKEDQVQSSFDWIERELEGADVLLNNAGITRETELVTPSNTQKLKEVIDTNVMGVIWCTREAFNNMKRRGGEGHVLIINSIAGHQVLNFIDVLPSFNIYPATKFAITAITETYRQEFQLHSNKIRVTGICPGAVNTNIFPEEIHFYVKDMARLEPANIADAVMYALRTPPHVQVHEITIKPMGEMF", "length": 251 }, "evidence": [ { "id": "MGI:2652816", "url": "https://alliancegenome.org/gene/MGI:2652816#orthology", "database": "AGR" }, { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VU92-1", "protein_name": "Uncharacterized protein", "gene_name": "FOHSDR", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MERWCNKVAVVSGASAGIGAACTRALIGAGMIVVGLARRHERVEKLRSGLSLEQQSRLHAIKCDITQEDQVLKAFDWTCRQLGGVDVLVSNAGIIGTGELSERDDGPAMRSTIETNIMGTVYCVRESFRSMKRRGTEGHVVIVNSVAGYQVPNLGPQLPSLNIYPATKFALRAMNEIYRQEFQRHKTAVRVSTVSPGIVDTVILPEQIQGIIKQHMPMLRSDDVADAVLWAIGTPPNVQVHNITIKPQGEKF", "length": 252 }, "evidence": [ { "id": "MGI:2652816", "url": "https://alliancegenome.org/gene/MGI:2652816#orthology", "database": "AGR" }, { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VYU9-1", "protein_name": "17-beta-estradiol 17-dehydrogenase", "gene_name": "Dmel\\CG9360", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDRWLNRVAVVTGASSGIGAACCKDLVSKGLVVVGLARREDRLQELKASLPADQASRFHGRKCDVSQEQEVIDAFAWIDATLGGADVLVNNAGIVRLGVGITHEGNGADLRAILDTNVLGVSWCTREAFKSLKRRNVNDGHILIVNSVAGHRVINNPGITMGMYSPSKYAVTALTEVLRQEFHNNKTQTKITSISPGAVDTEIIDKEALVGIPDFPMLRSEDVADAISYCIQTPPNVQIHELTIKPVGETL", "length": 251 }, "evidence": [ { "id": "MGI:2652816", "url": "https://alliancegenome.org/gene/MGI:2652816#orthology", "database": "AGR" }, { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VZ19-1", "protein_name": "1.1.1.270", "gene_name": "Antdh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MERWQNRVAVVTGASSGIGSAIAKDLVLAGMTVVGLARRVDRVKELQRELPAEKRGKLFALYCDVGNESSVNEAFDWIIQKLGAIDVLVNNAGTLQPGYLVDMNPAVMQQVLQTNIMGIVLCTQRAVRSMRERKFDGHVVLINSILGHKTMTATEGVAPDVNVYPPSKHAVTALAEGYRQEFFGLGTRIKITSVSPGVVDTEIVPDSIREAIKDRMLHSEDIAQGVLYAIATPPHVQVHELIIKPLGETM", "length": 250 }, "evidence": [ { "id": "MGI:2652816", "url": "https://alliancegenome.org/gene/MGI:2652816#orthology", "database": "AGR" }, { "id": "HGNC:28639", "url": "https://alliancegenome.org/gene/HGNC:28639#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "estradiol 17-beta-dehydrogenase [NAD(P)+] activity", "id": "GO:0004303", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004303", "evidence": [ { "database": "UniProtKB", "id": "A5WUM7", "url": "https://www.uniprot.org/uniprotkb/A5WUM7" } ], "pmid": "" }, { "name": "3-beta-hydroxysteroid 3-dehydrogenase (NADP+) activity", "id": "GO:0000253", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000253", "evidence": [ { "database": "UniProtKB", "id": "A5WUM7", "url": "https://www.uniprot.org/uniprotkb/A5WUM7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "24616", "name": "", "equation": "17beta-estradiol + NADP(+) = estrone + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q6P3L6-1", "Q6QA33-1", "F1QDB3-1", "F1R5X7-1", "A5WUM7-1", "F1QUP2-1" ], "evidence": [ { "id": "24616", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/24616" } ] }, { "id": "34787", "name": "", "equation": "a 3beta-hydroxysteroid + NADP(+) = a 3-oxosteroid + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1QDB3-1", "F1R5X7-1", "A5WUM7-1" ], "evidence": [ { "id": "34787", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/34787" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A5WUM7", "gene_name": "dhrs11a", "activity": [ { "ec_number": "1.1.1.270", "activity": "3-dehydro-4alpha-methylzymosterol + NADPH + H(+) = 4alpha-methylzymosterol + NADP(+).", "evidence": [ { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7" } ] }, { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7" } ] }, { "ec_number": "1.1.1.62", "activity": "", "evidence": [ { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7" } ] }, { "ec_number": "1.1.1.270", "activity": "", "evidence": [ { "id": "A5WUM7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUM7" } ] } ] }, { "uniprot_ac": "F1QDB3", "gene_name": "dhrs11b.2", "activity": [ { "ec_number": "1.1.1.270", "activity": "3-dehydro-4alpha-methylzymosterol + NADPH + H(+) = 4alpha-methylzymosterol + NADP(+).", "evidence": [ { "id": "F1QDB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QDB3" } ] }, { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "F1QDB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QDB3" } ] }, { "ec_number": "1.1.1.62", "activity": "", "evidence": [ { "id": "F1QDB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QDB3" } ] }, { "ec_number": "1.1.1.270", "activity": "", "evidence": [ { "id": "F1QDB3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QDB3" } ] } ] }, { "uniprot_ac": "F1QUP2", "gene_name": "hsd17b1", "activity": [ { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "F1QUP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QUP2" } ] }, { "ec_number": "1.1.1.62", "activity": "", "evidence": [ { "id": "F1QUP2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QUP2" } ] } ] }, { "uniprot_ac": "F1R5X7", "gene_name": "dhrs11b.1", "activity": [ { "ec_number": "1.1.1.270", "activity": "3-dehydro-4alpha-methylzymosterol + NADPH + H(+) = 4alpha-methylzymosterol + NADP(+).", "evidence": [ { "id": "F1R5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R5X7" } ] }, { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "F1R5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R5X7" } ] }, { "ec_number": "1.1.1.270", "activity": "", "evidence": [ { "id": "F1R5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R5X7" } ] }, { "ec_number": "1.1.1.62", "activity": "", "evidence": [ { "id": "F1R5X7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1R5X7" } ] } ] }, { "uniprot_ac": "Q6P3L6", "gene_name": "hsd17b12a", "activity": [ { "ec_number": "1.1.1.330", "activity": "a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP(+) = a very-long-chain 3-oxoacyl-CoA + NADPH + H(+).", "evidence": [ { "id": "Q6P3L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6P3L6" } ] }, { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "Q6P3L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6P3L6" } ] }, { "ec_number": "1.1.1.330", "activity": "", "evidence": [ { "id": "Q6P3L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6P3L6" } ] } ] }, { "uniprot_ac": "Q6QA33", "gene_name": "hsd17b12b", "activity": [ { "ec_number": "1.1.1.330", "activity": "a very-long-chain (3R)-3-hydroxyacyl-CoA + NADP(+) = a very-long-chain 3-oxoacyl-CoA + NADPH + H(+).", "evidence": [ { "id": "Q6QA33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6QA33" } ] }, { "ec_number": "1.1.1.62", "activity": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "Q6QA33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6QA33" } ] }, { "ec_number": "1.1.1.330", "activity": "", "evidence": [ { "id": "Q6QA33", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q6QA33" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.1.1.270", "ec_name": "3-dehydro-4alpha-methylzymosterol + NADPH + H(+) = 4alpha-methylzymosterol + NADP(+).", "evidence": [ { "id": "1.1.1.270", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.270" }, { "id": "1.1.1.270", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.1.270" } ] }, { "ec_number": "1.1.1.62", "ec_name": "17beta-estradiol + NAD(+) = estrone + NADH + H(+).", "evidence": [ { "id": "1.1.1.62", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.62" }, { "id": "1.1.1.62", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.1.62" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5WUU0-1", "uniprot_ac": "A5WUU0", "uniprot_id": "A5WUU0_DANRE", "mass": { "chemical_mass": 40675.0, "monoisotopic_mass": 40675.0 }, "refseq": { "ac": "NP_001093510", "name": "dnaJ homolog subfamily B member 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093510" }, "gene_names": [ { "name": "dnajb5", "type": "recommended", "evidence": [ { "id": "A5WUU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUU0" } ] }, { "name": "dnajb5", "type": "synonym", "evidence": [ { "id": "NP_001093510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093510" } ] }, { "name": "si:dkey-165i4.4", "type": "synonym", "evidence": [ { "id": "NP_001093510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093510" }, { "id": "A5WUU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUU0" } ] } ], "protein_names": [ { "name": "DnaJ (Hsp40) homolog, subfamily B, member 5", "type": "synonym", "evidence": [ { "id": "NP_001093510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093510" } ] }, { "name": "DnaJ homolog subfamily B member 5", "type": "synonym", "evidence": [ { "id": "A5WUU0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WUU0/entry#names_and_taxonomy" } ] }, { "name": "dnaJ homolog subfamily B member 5", "type": "synonym", "evidence": [ { "id": "NP_001093510", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093510" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588721.3656640.1, SRR32588730.12663043.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476780, SAMEA4476782 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jul 26, 2007 this sequence version replaced XP_697951.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001093510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093510" } ] }, { "annotation": "Critical role of zebrafish dnajb5 in myocardial proliferation and regeneration.", "evidence": [ { "database": "RefSeq", "id": "NP_001093510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093510" }, { "database": "PubMed", "id": "33191150", "url": "https://glygen.org/publication/PubMed/33191150" } ] } ], "disease": [ { "disease_id": "DOID:0081353", "recommended_name": { "id": "DOID:0081353", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0081353", "name": "congenital myopathy 21", "description": "A congenital myopathy that is characterized by diaphragmatic weakness and spinal rigidity and that has_material_basis_in homozygous mutation in the DNAJB4 gene on chromosome 1p31." }, "synonyms": [ { "id": "DOID:0081353", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0081353", "name": "congenital myopathy 21 with early respiratory failure", "description": "" }, { "id": "MONDO:0957224", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0957224", "name": "congenital myopathy 21 with early respiratory failure", "description": "" }, { "id": "MIM:620326", "resource": "MIM", "url": "https://www.omim.org/entry/620326", "name": "Congenital myopathy 21 with early respiratory failure", "description": "Congenital myopathy 21 with early respiratory failure" } ], "unlinked_id_list": [], "evidence": [ { "id": "0081353", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081353" } ] }, { "disease_id": "DOID:0110305", "recommended_name": { "id": "DOID:0110305", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110305", "name": "autosomal dominant limb-girdle muscular dystrophy type 1", "description": "An autosomal dominant limb-girdle muscular dystrophy that has_material_basis_in heterozygous mutation in the DNAJB6 gene on chromosome 7q36." }, "synonyms": [ { "id": "DOID:0110305", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110305", "name": "autosomal dominant limb-girdle muscular dystrophy type 1E", "description": "" }, { "id": "DOID:0110305", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110305", "name": "muscular dystrophy limb-girdle type 1D", "description": "" }, { "id": "DOID:0110305", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0110305", "name": "muscular dystrophy limb-girdle type 1E", "description": "" }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "autosomal dominant limb-girdle muscular dystrophy type 1D (DNAJB6)", "description": "Autosomal dominant limb-girdle muscular dystrophy type 1D (LGMD1D) is a subtype of autosomal dominant limb-girdle muscular dystrophy characterized by an adult-onset of slowly progressive, proximal pelvic girdle weakness, with none, or only minimal, shoulder girdle involvement, and absence of cardiac and respiratory symptoms. Mild to moderate elevated creatine kinase serum levels and gait abnormalities are frequently observed. LGMD1D is caused by heterozygous missense mutations in the DNAJB6 gene at chr. 7q36.3." }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "DNAJB6 autosomal dominant limb-girdle muscular dystrophy", "description": "" }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "LGMD1D", "description": "" }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "LGMD1D (DNAJB6)", "description": "" }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "autosomal dominant limb-girdle muscular dystrophy caused by mutation in DNAJB6", "description": "" }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "muscular dystrophy, limb-girdle, autosomal dominant 1", "description": "" }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "LGMD1E", "description": "" }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "LGMD1E (Bushby and Beckmann, 2003)", "description": "" }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "autosomal dominant limb-girdle muscular dystrophy type 1E", "description": "" }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "limb-girdle muscular dystrophy type 1D", "description": "" }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "muscular dystrophy limb-girdle type 1E", "description": "" }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "muscular dystrophy, limb-girdle, type 1D", "description": "" }, { "id": "MONDO:0021018", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0021018", "name": "muscular dystrophy, limb-girdle, type 1E", "description": "" }, { "id": "MIM:603511", "resource": "MIM", "url": "https://www.omim.org/entry/603511", "name": "Muscular dystrophy, limb-girdle, autosomal dominant 1", "description": "Muscular dystrophy, limb-girdle, autosomal dominant 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0110305", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0110305" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WUU0", "url": "https://www.uniprot.org/uniprotkb/A5WUU0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dnajb5", "url": "https://www.uniprot.org/uniprotkb/A5WUU0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-308", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-308", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000052881", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000052881", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd10747", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd10747", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "569466", "url": "https://www.ncbi.nlm.nih.gov/gene/569466", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008971", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008971", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569466", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569466", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IVFHIVE", "url": "https://omabrowser.org/oma/group/IVFHIVE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5WUU0", "url": "https://www.orthodb.org/?gene=A5WUU0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24078", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24078", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24078:SF567", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24078:SF567", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00226", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00226", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01556", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01556", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001093510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093510", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5WUU0", "url": "https://www.uniprot.org/uniprotkb/A5WUU0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WUU0-1", "url": "https://www.uniprot.org/uniprotkb/A5WUU0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-308", "url": "https://zfin.org/ZDB-GENE-070705-308", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGKDYYKILGIPSGSNEDEIKKAYRKMALKFHPDKNKDPNAEEKFKEIAEAYEVLSDPKKRVIYDQYGEDGLKTGGTGSSSGQGTTYHYTFHGDPHATFASFFGGSNPFDIFFGSSRQRGNTNGFPDHGDHDMDIDMDGEDDPFSSFSHFGFNGVNGFHHGGGRRHRNEPLHGGRKKLQDPPVVHELKVSLEEIFHGCTKRMRITRRRLNPDRKTMRTEDKILNIVIKRGWKEGTKITFPKEGDETPENIPADIAFVLKDKGHPLFRRDGSNIIYTTKIGLKEALCGCTVNIPTIDNRAITLPCNDIIKPGTIKRLRGEGLPFPKNPSQRGDLIVEFQVRFPDRIPPQSREIIKQHLPQS", "length": 360, "header": "tr|A5WUU0-1|A5WUU0_DANRE Isoform 1 of DnaJ homolog subfamily B member 5 OS=Danio rerio OX=7955 GN=dnajb5 PE=4 SV=1 CANONICAL=A5WUU0-1" }, "isoforms": [ { "isoform_ac": "A5WUU0-1", "url": "https://www.uniprot.org/uniprotkb/A5WUU0/entry#A5WUU0-1", "sequence": { "sequence": "MGKDYYKILGIPSGSNEDEIKKAYRKMALKFHPDKNKDPNAEEKFKEIAEAYEVLSDPKKRVIYDQYGEDGLKTGGTGSSSGQGTTYHYTFHGDPHATFASFFGGSNPFDIFFGSSRQRGNTNGFPDHGDHDMDIDMDGEDDPFSSFSHFGFNGVNGFHHGGGRRHRNEPLHGGRKKLQDPPVVHELKVSLEEIFHGCTKRMRITRRRLNPDRKTMRTEDKILNIVIKRGWKEGTKITFPKEGDETPENIPADIAFVLKDKGHPLFRRDGSNIIYTTKIGLKEALCGCTVNIPTIDNRAITLPCNDIIKPGTIKRLRGEGLPFPKNPSQRGDLIVEFQVRFPDRIPPQSREIIKQHLPQS", "length": 360, "header": "tr|A5WUU0-1|A5WUU0_DANRE Isoform 1 of DnaJ homolog subfamily B member 5 OS=Danio rerio OX=7955 GN=dnajb5 PE=4 SV=1 CANONICAL=A5WUU0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Exome sequence analysis suggests that genetic burden contributes to phenotypic variability and complex neuropathy.", "journal": "Cell Rep.", "date": "2015", "authors": "Gonzaga-Jauregui C, Harel T, Gambin T, Kousi M, Griffin LB, Francescatto L, Ozes B, Karaca E, Jhangiani SN, Bainbridge MN, Lawson KS, Pehlivan D, Okamoto Y, Withers M, Mancias P, Slavotinek A, Reitnauer PJ, Goksungur MT, Shy M, Crawford TO, Koenig M, Willer J, Flores BN, Pediaditrakis I, Us O, Wiszniewski W, Parman Y, Antonellis A, Muzny DM, Katsanis N, Battaloglu E, Boerwinkle E, Gibbs RA, Lupski JR", "evidence": [ { "database": "UniProtKB", "id": "A5WUU0", "url": "https://www.uniprot.org/uniprotkb/A5WUU0" } ], "reference": [ { "type": "PubMed", "id": "26257172", "url": "https://glygen.org/publication/PubMed/26257172" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A5WUU0", "url": "https://www.uniprot.org/uniprotkb/A5WUU0" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Critical role of zebrafish dnajb5 in myocardial proliferation and regeneration.", "journal": "J. Genet. Genomics", "date": "2020", "authors": "Pang M, Xiong C, Xiao C, Du J, Zheng L, Bai L, Zhu X, Xiong JW", "evidence": [ { "database": "UniProtKB", "id": "A5WUU0", "url": "https://www.uniprot.org/uniprotkb/A5WUU0" }, { "database": "RefSeq", "id": "NP_001093510", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093510" } ], "reference": [ { "type": "PubMed", "id": "33191150", "url": "https://glygen.org/publication/PubMed/33191150" } ] } ], "pathway": [ { "id": "dre:569466", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569466", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K9H9-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member B5", "gene_name": "Dnajb5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFKRTVLSCPPPAAPPLQARGAFRSFPHFWGEDFLASLMFKIQLEPLKLRAWTLNGFVKFRNKEPSTGPVAVMGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRSLYDQYGEEGLKTGGGTSGGSGGSFHYTFHGDPHATFASFFGGSNPFDIFFASSRSTRPFSGFDPDDMDVDEDEDPFGAFGRFGFNGLSRGPRRAPEPLYPRRKVQDPPVVHELRVSLEEIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDNIPADIVFVLKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDGRVIPLPCNDVIKPGTVKRLRGEGLPFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLPCS", "length": 420 }, "evidence": [ { "id": "RGD:1307453", "url": "https://alliancegenome.org/gene/RGD:1307453#orthology", "database": "AGR" }, { "id": "MGI:1930018", "url": "https://alliancegenome.org/gene/MGI:1930018#orthology", "database": "AGR" }, { "id": "HGNC:14887", "url": "https://alliancegenome.org/gene/HGNC:14887#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-308", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-308#orthology", "database": "AGR" }, { "id": "FB:FBgn0030207", "url": "https://alliancegenome.org/gene/FB:FBgn0030207#orthology", "database": "AGR" }, { "id": "FB:FBgn0263106", "url": "https://alliancegenome.org/gene/FB:FBgn0263106#orthology", "database": "AGR" }, { "id": "FB:FBgn0031322", "url": "https://alliancegenome.org/gene/FB:FBgn0031322#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" }, { "id": "A5WUU0", "url": "https://omabrowser.org/oma/group/A5WUU0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1PA47-1", "protein_name": "DnaJ homolog subfamily B member 1b", "gene_name": "dnajb1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVKMGKDYYSVLGIQKGASDDEIKKAYRKQALKYHPDKNKSAGAEEKFKEIAEAYDVLSDPKKKDIYDRFGEEGLKGGAPGGGGGGGNYTYTFQGDPHAMFSEFFGGRNPFEHIFGHNGGMDENMETDDPFASFGMGGIGGFPRSFTTHSHGGRMERKQDPAVIHDLRVSLDEVFTGCTKKMKISRKRLNPDGRTTRSEDKILTVEVKKGWKEGTKITFPREGDETPSNIPADVVFVLKDKPHPVYKRDGSDIIYPAKITLKEALCGCVINVPTLDGRTVKVTSQDIVRPGMKRRLTGEGLPLPKAPDRRGDLVVEYEVRFPEKLSQNAKDTIANVLPAS", "length": 340 }, "evidence": [ { "id": "FB:FBgn0263106", "url": "https://alliancegenome.org/gene/FB:FBgn0263106#orthology", "database": "AGR" }, { "id": "FB:FBgn0031322", "url": "https://alliancegenome.org/gene/FB:FBgn0031322#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZUU5-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member B1", "gene_name": "Dnajb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSCVTQRAAAIGRCGATHREGRKVLEGWRDLEASAGRVYRVRDGAAAEPEAATAGRRWPWARTTTRRWAWPAARPTTRSSGPTAARRCATTRTRTRSPAPRRSSRRSPRPTTCSATRASARFSTAMERKVRVRAARVTRRLTGEETEALGASLRLRRGTDGPGIPRRRCLLHLLSNRRPQTGGGALGLKGGGPSGGSSGGANGTSFSYTFHGDPHAMFAEFFGGRNPFDTFFGQRNGEEGMDIDDPFSSFPMGMGGFTNMNFGRSRPTQEPTRKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKRGWKEGTKITFPKEGDQTSNNIPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPVVFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLVIEFEVIFPDRIPISSRTILEQVLPI", "length": 456 }, "evidence": [ { "id": "FB:FBgn0263106", "url": "https://alliancegenome.org/gene/FB:FBgn0263106#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75953-3", "protein_name": "DnaJ homolog subfamily B member 5", "gene_name": "DNAJB5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRGLYDQYGEEGLKTGGGTSGGSSGSFHYTFHGDPHATFASFFGGSNPFDIFFASSRSTRPFSGFDPDDMDVDEDEDPFGAFGRFGFNGLSRGPRRAPEPLYPRRKVQDPPVVHELRVSLEEIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDNIPADIVFVLKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDGRVIPLPCNDVIKPGTVKRLRGEGLPFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLPCS", "length": 348 }, "evidence": [ { "id": "RGD:1307453", "url": "https://alliancegenome.org/gene/RGD:1307453#orthology", "database": "AGR" }, { "id": "MGI:1930018", "url": "https://alliancegenome.org/gene/MGI:1930018#orthology", "database": "AGR" }, { "id": "HGNC:14887", "url": "https://alliancegenome.org/gene/HGNC:14887#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-308", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-308#orthology", "database": "AGR" }, { "id": "FB:FBgn0030207", "url": "https://alliancegenome.org/gene/FB:FBgn0030207#orthology", "database": "AGR" }, { "id": "FB:FBgn0263106", "url": "https://alliancegenome.org/gene/FB:FBgn0263106#orthology", "database": "AGR" }, { "id": "FB:FBgn0031322", "url": "https://alliancegenome.org/gene/FB:FBgn0031322#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" }, { "id": "A5WUU0", "url": "https://omabrowser.org/oma/group/A5WUU0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O89114-1", "protein_name": "DnaJ homolog subfamily B member 5", "gene_name": "Dnajb5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRSLYDQYGEEGLKTGGGSSGGSGGSFHYTFHGDPHATFASFFGGSNPFDIFFASSRSTRPFSGFDPDDMDVDEDEDPFGAFGRFGFNGLSRGPRRAPEPLYPRRKVQDPPVVHELRVSLEEIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDNIPADIVFVLKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDGRVIPLPCNDVIKPGTVKRLRGEGLPFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLPCS", "length": 348 }, "evidence": [ { "id": "RGD:1307453", "url": "https://alliancegenome.org/gene/RGD:1307453#orthology", "database": "AGR" }, { "id": "MGI:1930018", "url": "https://alliancegenome.org/gene/MGI:1930018#orthology", "database": "AGR" }, { "id": "HGNC:14887", "url": "https://alliancegenome.org/gene/HGNC:14887#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-308", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-308#orthology", "database": "AGR" }, { "id": "FB:FBgn0030207", "url": "https://alliancegenome.org/gene/FB:FBgn0030207#orthology", "database": "AGR" }, { "id": "FB:FBgn0263106", "url": "https://alliancegenome.org/gene/FB:FBgn0263106#orthology", "database": "AGR" }, { "id": "FB:FBgn0031322", "url": "https://alliancegenome.org/gene/FB:FBgn0031322#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" }, { "id": "A5WUU0", "url": "https://omabrowser.org/oma/group/A5WUU0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P25294-1", "protein_name": "Protein SIS1", "gene_name": "SIS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVKETKLYDLLGVSPSANEQELKKGYRKAALKYHPDKPTGDTEKFKEISEAFEILNDPQKREIYDQYGLEAARSGGPSFGPGGPGGAGGAGGFPGGAGGFSGGHAFSNEDAFNIFSQFFGGSSPFGGADDSGFSFSSYPSGGGAGMGGMPGGMGGMHGGMGGMPGGFRSASSSPTYPEEETVQVNLPVSLEDLFVGKKKSFKIGRKGPHGASEKTQIDIQLKPGWKAGTKITYKNQGDYNPQTGRRKTLQFVIQEKSHPNFKRDGDDLIYTLPLSFKESLLGFSKTIQTIDGRTLPLSRVQPVQPSQTSTYPGQGMPTPKNPSQRGNLIVKYKVDYPISLNDAQKRAIDENF", "length": 352 }, "evidence": [ { "id": "RGD:1307453", "url": "https://alliancegenome.org/gene/RGD:1307453#orthology", "database": "AGR" }, { "id": "MGI:1930018", "url": "https://alliancegenome.org/gene/MGI:1930018#orthology", "database": "AGR" }, { "id": "HGNC:14887", "url": "https://alliancegenome.org/gene/HGNC:14887#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-308", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-308#orthology", "database": "AGR" }, { "id": "FB:FBgn0030207", "url": "https://alliancegenome.org/gene/FB:FBgn0030207#orthology", "database": "AGR" }, { "id": "FB:FBgn0263106", "url": "https://alliancegenome.org/gene/FB:FBgn0263106#orthology", "database": "AGR" }, { "id": "FB:FBgn0031322", "url": "https://alliancegenome.org/gene/FB:FBgn0031322#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P25685-1", "protein_name": "DnaJ homolog subfamily B member 1", "gene_name": "DNAJB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEGLKGSGPSGGSGGGANGTSFSYTFHGDPHAMFAEFFGGRNPFDTFFGQRNGEEGMDIDDPFSGFPMGMGGFTNVNFGRSRSAQEPARKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKKGWKEGTKITFPKEGDQTSNNIPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPVVFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLIIEFEVIFPERIPQTSRTVLEQVLPI", "length": 340 }, "evidence": [ { "id": "FB:FBgn0263106", "url": "https://alliancegenome.org/gene/FB:FBgn0263106#orthology", "database": "AGR" }, { "id": "FB:FBgn0031322", "url": "https://alliancegenome.org/gene/FB:FBgn0031322#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P59910-1", "protein_name": "DnaJ homolog subfamily B member 13", "gene_name": "DNAJB13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGQDYYSVLGITRNSEDAQIKQAYRRLALKHHPLKSNEPSSAEIFRQIAEAYDVLSDPMKRGIYDKFGEEGLKGGIPLEFGSQTPWTTGYVFHGKPEKVFHEFFGGNNPFSEFFDAEGSEVDLNFGGLQGRGVKKQDPQVERDLYLSLEDLFFGCTKKIKISRRVLNEDGYSSTIKDKILTIDVKPGWRQGTRITFEKEGDQGPNIIPADIIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLDDRLLNIPINDIIHPKYFKKVPGEGMPLPEDPTKKGDLFIFFDIQFPTRLTPQKKQMLRQALLT", "length": 316 }, "evidence": [ { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q24133-1", "protein_name": "DnaJ protein homolog 1", "gene_name": "DnaJ-1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKDFYKILGLERKASDDEIKKAYRKLALKYHPDKNKSPQAEERFKEIAEAYEVLSDKKKRDIFDNYGEDGLKGGQPGPDGGGQPGAYTYQFHGDPRATFAQFFGSSDPFGAFFTGGDNMFSGGQGGNTNEIFWNIGGDDMFAFNAQAPSRKRQQDPPIEHDLFVSLEEVDKGCIKKMKISRMATGSNGPYKEEKVLRITVKPGWKAGTKITFPQEGDSAPNKTPADIVFIIRDKPHSLFKREGIDLKYTAQISLKQALCGALVSVPTLQGSRIQVNPNHEIIKPTTTRRINGLGLPVPKEPSRRGDLIVSFDIKFPDTLAPSLQNQLSELLPN", "length": 334 }, "evidence": [ { "id": "RGD:1307453", "url": "https://alliancegenome.org/gene/RGD:1307453#orthology", "database": "AGR" }, { "id": "MGI:1930018", "url": "https://alliancegenome.org/gene/MGI:1930018#orthology", "database": "AGR" }, { "id": "HGNC:14887", "url": "https://alliancegenome.org/gene/HGNC:14887#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-308", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-308#orthology", "database": "AGR" }, { "id": "FB:FBgn0263106", "url": "https://alliancegenome.org/gene/FB:FBgn0263106#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q54SQ0-1", "protein_name": "Heat shock protein DnaJ family protein", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MMKIKSLIILVIVVCLSVFTYAGRDFYDILGITRDSSPADIKRSYRKLSVKYHPDKNPDKKDMYIEINSAYETLSDPEKRRIYDQYGEEGLKQNHGGGGFDPFDIFSVFGGGGRHQQQAQQQQRGADIELELEVTLKDLYIGKTTKVTHKKQVLCTKCRGSGAKKASDVTTCGGCKGSGIKLKVQQLGPGFVQQIQSACDECGGKGKKVTSKCPHCHGKKVEIGEETYTIEIERGMNDQSIIKLEQLGEESPDVTPGDIIFKIVTSPDSKFRRSGDNLYYDMSITLLEALVGFKKEIDHLDGHKVEINRVDVTSPGLTIKVDGEGMPHHSFPSQTGDLYVIFNIIFPQKVSAEDKLSFEKLLK", "length": 363 }, "evidence": [ { "id": "A5WUU0", "url": "https://omabrowser.org/oma/group/A5WUU0/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q5BIP8-1", "protein_name": "DnaJ homolog subfamily B member 5", "gene_name": "DNAJB5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGKDYYKILGIPSGANEDEIKKAYRKMALKYHPDKNKEPNAEEKFKEIAEAYDVLSDPKKRGLYDQYGEEGLKTGGGSSGGSSGSFHYTFHGDPHATFASFFGGSNPFDIFFASSRSARPFSGFDPDDMDVDEDDDPFGAFGRFGFNGLSRGPRRAPEPLYPRRKVQDPPVVHELRVSLEEIYHGSTKRMKITRRRLNPDGRTVRTEDKILHIVIKRGWKEGTKITFPKEGDATPDNIPADIVFVLKDKPHAHFRRDGTNVLYSALISLKEALCGCTVNIPTIDGRVIPLPCNDVIKPGTVKRLRGEGLPFPKVPTQRGDLIVEFKVRFPDRLTPQTRQILKQHLPCS", "length": 348 }, "evidence": [ { "id": "A5WUU0", "url": "https://omabrowser.org/oma/group/A5WUU0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5XIP0-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member B4", "gene_name": "Dnajb4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKDYYHILGIEKGATDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGANPFEIFFGRRMGGGRDSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPIIHELKVSLEEIYSGCTKRMKISRKRLNPDGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKEHPKFKRDGSNIVYTAKISLREALCGCSINVPTMDGRNIPMSVTDIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFDVSFPDVISAASKEILRKHLPAS", "length": 337 }, "evidence": [ { "id": "FB:FBgn0263106", "url": "https://alliancegenome.org/gene/FB:FBgn0263106#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80Y75-1", "protein_name": "DnaJ homolog subfamily B member 13", "gene_name": "Dnajb13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLDYYAVLQVTRNSEDAQIKKAYRKLALKNHPLKSSEPGAPEIFKQIAEAYDVLSDPVKRGIYDKFGEEGLKGGIPLEFGSQTPWTTGYVFHGNPDKVFHEFFGGDNPFSEFFDAEGNDIDLNFGGLWGRGVQKQDPPIERDLYLSLEDLFFGCTKKIKISRRVLNEDRYSSTIKDKILTIDVRPGWRQGTRITFEKEGDQGPNIIPADIIFIVKEKLHPRFRREHDNLFFVYPIPLGKALTCCTVEVKTLDDRLLNIPINDIVHPKYFKIVPGEGMPLPENPSKKGDLFIFFDIQFPTRLTPQKKQMLRQALLT", "length": 316 }, "evidence": [ { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D832-1", "protein_name": "DnaJ homolog subfamily B member 4", "gene_name": "Dnajb4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKDYYHILGIDKGATDEDVKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGRDSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPIIHELKVSLEEIYSGCTKRMKISRKRLNPDGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFVIKDKEHPKFKRDGSNIVYTAKISLREALCGCSLNVPTMDGRNLPMSVTDIVKPGMRRRVIGYGLPFPKNPDQRGDLLIEFDVSFPDVISAASKEILRKHLPAS", "length": 337 }, "evidence": [ { "id": "FB:FBgn0263106", "url": "https://alliancegenome.org/gene/FB:FBgn0263106#orthology", "database": "AGR" }, { "id": "FB:FBgn0031322", "url": "https://alliancegenome.org/gene/FB:FBgn0031322#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9QYJ3-1", "protein_name": "DnaJ homolog subfamily B member 1", "gene_name": "Dnajb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKDYYQTLGLARGASDDEIKRAYRRQALRYHPDKNKEPGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEGLKGGSPSGGSSGGANGTSFSYTFHGDPHAMFAEFFGGRNPFDTFFGQRNGEEGMDIDDTFSSFPMGMGGFTNMNFGRSRPSQEPTRKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIRNEDKILTIEVKRGWKEGTKITFPKEGDQTSNNIPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPVVFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLVIEFEVIFPERIPVSSRTILEQVLPI", "length": 340 }, "evidence": [ { "id": "FB:FBgn0263106", "url": "https://alliancegenome.org/gene/FB:FBgn0263106#orthology", "database": "AGR" }, { "id": "FB:FBgn0031322", "url": "https://alliancegenome.org/gene/FB:FBgn0031322#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UDY4-1", "protein_name": "DnaJ homolog subfamily B member 4", "gene_name": "DNAJB4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKDYYCILGIEKGASDEDIKKAYRKQALKFHPDKNKSPQAEEKFKEVAEAYEVLSDPKKREIYDQFGEEGLKGGAGGTDGQGGTFRYTFHGDPHATFAAFFGGSNPFEIFFGRRMGGGRDSEEMEIDGDPFSAFGFSMNGYPRDRNSVGPSRLKQDPPVIHELRVSLEEIYSGCTKRMKISRKRLNADGRSYRSEDKILTIEIKKGWKEGTKITFPREGDETPNSIPADIVFIIKDKDHPKFKRDGSNIIYTAKISLREALCGCSINVPTLDGRNIPMSVNDIVKPGMRRRIIGYGLPFPKNPDQRGDLLIEFEVSFPDTISSSSKEVLRKHLPAS", "length": 337 }, "evidence": [ { "id": "FB:FBgn0263106", "url": "https://alliancegenome.org/gene/FB:FBgn0263106#orthology", "database": "AGR" }, { "id": "FB:FBgn0031322", "url": "https://alliancegenome.org/gene/FB:FBgn0031322#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VPY9-1", "protein_name": "J domain-containing protein", "gene_name": "Dmel\\CG5001", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGKDYYKILGLPKTATDDEIKKAYRKLALRYHPDKNKAANAEDKFKEVAEAYEVLSDKSKREVYDKYGEDGLKSGGTRNGGPSSNSFTYQFHGDPRATFAQFFGNSNPFASFFDMGDNLFDKKVFDLDTEPDFFSSPFGGIGSRHGLGSGFRPSFRSHSFNVHTPFKKEQKQDPPVEHDLYVTLEEIYHGCVKKMKISRRIVQADGSSRKEEKFLAISIKPGWKSGTKVTFQKEGDQAPGKIPADIVFIIRDKPHAMFKREGSDLRYTARLTLKQALCGVVFQVPTMSGDKLRISTMQEIIKPNTVKRIQGYGLPFPKDTTRKGDLLVAFDIQFPEKLTAAQKEVLKDML", "length": 350 }, "evidence": [ { "id": "RGD:1307453", "url": "https://alliancegenome.org/gene/RGD:1307453#orthology", "database": "AGR" }, { "id": "MGI:1930018", "url": "https://alliancegenome.org/gene/MGI:1930018#orthology", "database": "AGR" }, { "id": "HGNC:14887", "url": "https://alliancegenome.org/gene/HGNC:14887#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-308", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-308#orthology", "database": "AGR" }, { "id": "FB:FBgn0031322", "url": "https://alliancegenome.org/gene/FB:FBgn0031322#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W2U5-1", "protein_name": "J domain-containing protein", "gene_name": "Dmel\\CG2887", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPKDYYKILGIQRTANDGEIRKAYHKQALRYHPDKNKSPQAEEIFKQVAKAYEVLSDKKKRGSYDSRNDKGTRRNTANQGSGFGDGTAFGSCGGGSGSGSGGGSGGGRQNNPRANFGRFFDNSESYSTFFEDIENDFDSDDDVLLGGGAGAPKRRCEQQSPQSSIEHVIYVALEDIANGCNRRMKISRASGRNGVDGVQYDRILTVKIPPGCKAGTKICFPNEGIQLPNLEPANVVFIIRDKPHPIFRRDGNNLLYTAEISLKDALCGLHVMVPTLLGRPMELKTDVGEVISPKSVRRILGYGLPDSINNSRRGSIVVRFSIQFPDAISKELASSLDRLLQN", "length": 342 }, "evidence": [ { "id": "RGD:1307453", "url": "https://alliancegenome.org/gene/RGD:1307453#orthology", "database": "AGR" }, { "id": "MGI:1930018", "url": "https://alliancegenome.org/gene/MGI:1930018#orthology", "database": "AGR" }, { "id": "HGNC:14887", "url": "https://alliancegenome.org/gene/HGNC:14887#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-308", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-308#orthology", "database": "AGR" }, { "id": "FB:FBgn0030207", "url": "https://alliancegenome.org/gene/FB:FBgn0030207#orthology", "database": "AGR" }, { "id": "SGD:S000004952", "url": "https://alliancegenome.org/gene/SGD:S000004952#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "A5WUU0", "url": "https://www.uniprot.org/uniprotkb/A5WUU0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "A5WUU0", "url": "https://www.uniprot.org/uniprotkb/A5WUU0" } ], "pmid": "" }, { "name": "protein-folding chaperone binding", "id": "GO:0051087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051087", "evidence": [ { "database": "UniProtKB", "id": "A5WUU0", "url": "https://www.uniprot.org/uniprotkb/A5WUU0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein folding", "id": "GO:0006457", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006457", "evidence": [ { "database": "UniProtKB", "id": "A5WUU0", "url": "https://www.uniprot.org/uniprotkb/A5WUU0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5WUU0", "database": "UniProtKB", "url": 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"type": "synonym", "evidence": [ { "id": "NP_001138287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138287" } ] }, { "name": "zmp:0000001044", "type": "synonym", "evidence": [ { "id": "NP_001138287", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138287" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from CT025908.13. On Jan 25, 2009 this sequence version replaced XP_001343597.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001138287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138287" } ] } ], "disease": [ { "disease_id": "DOID:0070531", "recommended_name": { "id": "DOID:0070531", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070531", "name": "foveal hypoplasia 2", "description": "A retinal disease characterized by foveal hypoplasia with decreased visual acuity and nystagmus that has_material_basis_in homozygous or compound heterozygous mutation in the SLC38A8 gene on chromosome 16q23.3. Optic nerve decussation defects and anterior segment dysgenesis are also frequently seen." }, "synonyms": [ { "id": "DOID:0070531", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070531", "name": "FVH2", "description": "" }, { "id": "DOID:0070531", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070531", "name": "foveal hypoplasia 2 with or without optic nerve misrouting and/or anterior segment dysgenesis", "description": "" }, { "id": "MONDO:0012216", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012216", "name": "foveal hypoplasia - optic nerve decussation defect - anterior segment dysgenesis syndrome", "description": "" }, { "id": "MONDO:0012216", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012216", "name": "FHONDA syndrome", "description": "" }, { "id": "MONDO:0012216", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012216", "name": "foveal hypoplasia - optic nerve decussation defect - anterior segment dysgenesis syndrome", "description": "" }, { "id": "MONDO:0012216", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012216", "name": "foveal hypoplasia 2, with or without optic nerve misrouting and/or anterior segment dysgenesis", "description": "" }, { "id": "MONDO:0012216", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012216", "name": "foveal hypoplasia type 2", "description": "" }, { "id": "MONDO:0012216", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012216", "name": "FVH2", "description": "" }, { "id": "MONDO:0012216", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012216", "name": "foveal hypoplasia 2", "description": "" }, { "id": "MIM:609218", "resource": "MIM", "url": "https://www.omim.org/entry/609218", "name": "Foveal hypoplasia 2", "description": "Foveal hypoplasia 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070531", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070531" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WVQ9", "url": "https://www.uniprot.org/uniprotkb/A5WVQ9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "slc38a8a", "url": "https://www.uniprot.org/uniprotkb/A5WVQ9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-121005-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121005-5", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100004247", "url": "https://www.ncbi.nlm.nih.gov/gene/100004247", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100004247", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004247", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A5WVQ9", "url": "https://www.orthodb.org/?gene=A5WVQ9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22950:SF226", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22950:SF226", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01490", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001138287", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138287", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5WVQ9", "url": "https://www.uniprot.org/uniprotkb/A5WVQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WVQ9-1", "url": "https://www.uniprot.org/uniprotkb/A5WVQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-121005-5", "url": "https://zfin.org/ZDB-GENE-121005-5", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEELAKESISFLSKSSLETNEPRLGSLGAVFIMLKSALGAGLLIFPWAFAKAGGIHFAVTVEMISLVFLISGLVILGYSSSVSGRNTYQGVVTDICGPAIGKLCEICYVFNLFFISVAFLVIVADQLHKLCLSMYELITGLPESEMPYHWYTDQRFALFLLCLLFIFPLSVPKEISIQKYTSVLGTFAAAYLTVAIVVKYHMRPIHEINLSPLYSSGISSWDSVFSVIPTICFGFQCHEACVAVYSSMENRRLSHWVFISVLSMLICLLIYSLTGVFGYLTFGKNVAPDILMSYSGGDVTMIVARLLFGISIITIYPIIVLLGRSVIQDPLLRRRLKHTAVTESYESRTRVALTTAWVTVTLLIAVFIPDISKVISVVGGVSAFFIFIFPGLCLIFVVQSESVSPTMRYLLVTWGMITLLCGTLIFGQSTSVAIMQLITEV", "length": 441, "header": "tr|A5WVQ9-1|A5WVQ9_DANRE Isoform 1 of Sodium-coupled neutral amino acid transporter 8a OS=Danio rerio OX=7955 GN=slc38a8a PE=3 SV=1 CANONICAL=A5WVQ9-1" }, "isoforms": [ { "isoform_ac": "A5WVQ9-1", "url": "https://www.uniprot.org/uniprotkb/A5WVQ9/entry#A5WVQ9-1", "sequence": { "sequence": "MEELAKESISFLSKSSLETNEPRLGSLGAVFIMLKSALGAGLLIFPWAFAKAGGIHFAVTVEMISLVFLISGLVILGYSSSVSGRNTYQGVVTDICGPAIGKLCEICYVFNLFFISVAFLVIVADQLHKLCLSMYELITGLPESEMPYHWYTDQRFALFLLCLLFIFPLSVPKEISIQKYTSVLGTFAAAYLTVAIVVKYHMRPIHEINLSPLYSSGISSWDSVFSVIPTICFGFQCHEACVAVYSSMENRRLSHWVFISVLSMLICLLIYSLTGVFGYLTFGKNVAPDILMSYSGGDVTMIVARLLFGISIITIYPIIVLLGRSVIQDPLLRRRLKHTAVTESYESRTRVALTTAWVTVTLLIAVFIPDISKVISVVGGVSAFFIFIFPGLCLIFVVQSESVSPTMRYLLVTWGMITLLCGTLIFGQSTSVAIMQLITEV", "length": 441, "header": "tr|A5WVQ9-1|A5WVQ9_DANRE Isoform 1 of Sodium-coupled neutral amino acid transporter 8a OS=Danio rerio OX=7955 GN=slc38a8a PE=3 SV=1 CANONICAL=A5WVQ9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Localization of genes encoding metallothionein-like protein (mt2 and smtb) in the brain of zebrafish.", "journal": "J. Chem. Neuroanat.", "date": "2015", "authors": "Teoh Seong Lin, Ogawa Satoshi, Parhar Ishwar S", "evidence": [ { "database": "UniProtKB", "id": "A5WVQ9", "url": "https://www.uniprot.org/uniprotkb/A5WVQ9" } ], "reference": [ { "type": "PubMed", "id": "26571427", "url": "https://glygen.org/publication/PubMed/26571427" } ] } ], "pathway": [ { "id": "dre:100004247", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004247", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BEJ3-1", "protein_name": "Sodium-coupled neutral amino acid transporter 3", "gene_name": "slc38a5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "METVNKMPNGHHDIPMNLEKEFTGFDALENMAEGDQFLSSKSNGKIETQFTDFEGKTSFGMSIFNLSNAIMGSGILGLAYAMANTGIILFVFLLITIALLSSYSIHLLLRSAGVVGIRAYEQLGYRAFGTPGKVVAGCIITLHNIGAMSSYLFIVKIELPHVIEGLTGLPDNSGHWYVDGRYLIIIVSVCVIFPLALMKRLGYLGYTSGFSLSCMVFFLISVIYKCLSNSGIDSESNQNEKCTFSNASMISSTTEINEINSTTEICEAKLLTINPQTAFTIPIIAFAFVCHPEVLPIYTELKNPSKKQMQKVANISILAMFVMYLLTAIFGYLTFFANVDSELLKMYNKNDILMLCVRLAVLVAVTLTVPVVLFPIRRAVLQLLFPEKPFSWVRHIIIAMCLLFAVNLLVIFVPNIRDIFGFIGATSAPSLIFILPGIFYIYIVPEEQEPLKSRPKILAILFVTLGFIFMIMSITFIIIEWVNGKQSVGGH", "length": 491 }, "evidence": [ { "id": "SGD:S000000185", "url": "https://alliancegenome.org/gene/SGD:S000000185#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58G4J0-1", "protein_name": "Sodium-coupled neutral amino acid transporter 8 isoform X1", "gene_name": "slc38a8b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSVSSLRSVSFGPYTEQMILVFPASMYAEPFAWLTSPQRANTGRTSPFPRTPCLLLGALGALSGDRKSNGDCDSSGPRIRFVSTGIFNKPTCLREHSLLCSGETTQSSSRNQMLRDAAIKCCLRAAALCRIGITWQIDGLHILPEESYLTVAFQLKTGLEALRMEELARESIRSISLLSKPARGSDVPRLGSFGAIFIMLKSALGAGLLNFPWAFEKAGGVNTAISVEMVSLVFLISGLVILGYASSISRQNTYHDVVRNVCGRRIGHLCEICFVFNLFMISVAFLVVVQDQLEKLCLSLYETVTGNTEAEMPHHWYTDYRFALSFMCLIIILPLSIPKEIGIQKYTSVMGTLAATYLSVAVIAKYYLKDTHTADLTPEHSQGLGSWASMFSVVPTICFGFQCHEASIAIYSSMENKKITHWVFISVTSMIFCLLIYTLTGVFGFLTFGRKVASDILMSYPGNDVVMIIARLLFGISIVTIYPIILLLGRSVILTQILRFWERRTIMTPVFEGRCRLILTILWITVTLLIAIFVPDMSEVISVIGGISAFFIFIFPGLCLIFVMQTEPINHRIRILLTGWGVVTIVIGAFIFGQSTTIAVMELAHKF", "length": 607 }, "evidence": [ { "id": "MGI:2685433", "url": "https://alliancegenome.org/gene/MGI:2685433#orthology", "database": "AGR" }, { "id": "HGNC:32434", "url": "https://alliancegenome.org/gene/HGNC:32434#orthology", "database": "AGR" }, { "id": "RGD:1560237", "url": "https://alliancegenome.org/gene/RGD:1560237#orthology", "database": "AGR" }, { "id": "SGD:S000000185", "url": "https://alliancegenome.org/gene/SGD:S000000185#orthology", "database": "AGR" }, { "id": "SGD:S000000921", "url": "https://alliancegenome.org/gene/SGD:S000000921#orthology", "database": "AGR" }, { "id": "SGD:S000001350", "url": "https://alliancegenome.org/gene/SGD:S000001350#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A2VCW5-1", "protein_name": "Sodium-coupled neutral amino acid transporter 5", "gene_name": "Slc38a5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAISCAVGMEMQEPKMNGTLSTGAAAGYRQEREGFLPTTHGPAPGRKPVQFLDFEGKTSFGMSVFNLSNAIMGSGILGLAYAMAHTGVIFFLALLLCIALLSSYSIHLLLTCASVVGIRAYEQLGQRAFGPAGKVVVAIIICLHNVGAMSSYLFIIKSELPLVIGTFLHMDPEGDWFLKGNLLIILVSLLIILPLALMKHLGYLGYTSSLSLTCMLFFLISVIYKKFQLGCVVSHNDTVVESEPAPLQAFNSSCEAKLFTVDSQMSYTVPIMAFAFVCHPEVLPIYTELCCPTQRRMQAVANMSIGAMFIMYGLTATFGYLTFYSTVKAEMLEMYTQEDLLILCVRLAVLLAVTLTVPVVLFPIRRALQQLLFPSKAFSWPRHVAIALILLILVNILVICVPTIRDIFGFIGSTSAPSLIFILPSVFYLRIVPADMEPLFSWPKIQALCFGVLGVLFMAISLGFMFANWATGQSRMSGH", "length": 479 }, "evidence": [ { "id": "SGD:S000000185", "url": "https://alliancegenome.org/gene/SGD:S000000185#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6NNN8-1", "protein_name": "Solute carrier family 38 member 8", "gene_name": "SLC38A8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGQTPGSRGLPEKPHPATAAATLSSMGAVFILMKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYAAAVSGQATYQGVVRGLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTLPLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRESHPSLSPASWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGFLTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGWGPSALADPSGLWVRMPLTILWVTVTLAMALFMPDLSEIVSIIGGISSFFIFIFPGLCLICAMGVEPIGPRVKCCLEVWGVVSVLVGTFIFGQSTAAAVWEMF", "length": 435 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-121005-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121005-5#orthology", "database": "AGR" }, { "id": "MGI:2685433", "url": "https://alliancegenome.org/gene/MGI:2685433#orthology", "database": "AGR" }, { "id": "HGNC:32434", "url": "https://alliancegenome.org/gene/HGNC:32434#orthology", "database": "AGR" }, { "id": "RGD:1560237", "url": "https://alliancegenome.org/gene/RGD:1560237#orthology", "database": "AGR" }, { "id": "SGD:S000000921", "url": "https://alliancegenome.org/gene/SGD:S000000921#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "D4A0Y7-1", "protein_name": "Solute carrier family 38, member 8", "gene_name": "Slc38a8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEGQTRGSRGLPEKPLPATTHPPLSSLGAVFILLKSALGAGLLNFPWAFYKAGGLVPTFLVALVSLVFLISGLVILGYAASVSGQTTYQGVVRELCGPAMGKLCEACFLTNLLMISVAFLRVIGDQLEKLCDSLLPDAPQPWYAAQSFTLPLISVLVIFPLSALRDIALQEYTSILGTLAACYLALVITVQYYLWPQGLIRQPGPLLSPSPWTSVFSVFPTICFGFQCHEAAVSIYCSMQNQSLPHWTLVSVLSLMACCLVYTLTGVYGFLTFGTEVSADILMSYPGNDTAIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWKKSYWATQGSPVLADPSGPWVRLPLTFLWVAVTLAMALFLPDLSEIIGVIGGLSAFFIFIFPGLCLISAVDTEPIGPRVKSRTTGSHGYHHEQFEEAGTDINRIGVVLPRRYCCVVWCEAQDCG", "length": 446 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-121005-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121005-5#orthology", "database": "AGR" }, { "id": "MGI:2685433", "url": "https://alliancegenome.org/gene/MGI:2685433#orthology", "database": "AGR" }, { "id": "HGNC:32434", "url": "https://alliancegenome.org/gene/HGNC:32434#orthology", "database": "AGR" }, { "id": "RGD:1560237", "url": "https://alliancegenome.org/gene/RGD:1560237#orthology", "database": "AGR" }, { "id": "SGD:S000000921", "url": "https://alliancegenome.org/gene/SGD:S000000921#orthology", "database": "AGR" }, { "id": "SGD:S000001350", "url": "https://alliancegenome.org/gene/SGD:S000001350#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P38176-1", "protein_name": "Vacuolar amino acid transporter 5", "gene_name": "AVT5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPSNVRSGVLTLLHTACGAGVLAMPFAFKPFGLMPGLITLTFCGICSLCGLLLQTRIAKYVPKSENASFAKLTQLINPSISVVFDFAIAVKCFGVGVSYLIIVGDLVPQIVQSIFYRNDDNMSGSQEHHMFLDRRLYITLIIVFVISPLCFKRSLNSLRYASMIAIVSVAYLSGLIIYHFVNRHQLERGQVYFMVPHGDSQSHSPLTTLPIFVFAYTCHHNMFSVINEQVDKSFKVIRRIPIFAIVLAYFLYIIIGGTGYMTFGENIVGNILTLYPNSISTTIGRLAMLLLVMLAFPLQCHPCRSSVKNIIIFIENFRKGKLYDNRASFIPLDNFNSEDPQEAPTQQNNEEPNLRSESLRHINIITLCILLFSYLLAISITSLAKVLAIVGATGSTSISFILPGLFGYKLIGSEFTGTNERVPTSIKIFKYLSLSLFIWGIAVMVASLSAIVFLGTSSH", "length": 459 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-121005-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121005-5#orthology", "database": "AGR" }, { "id": "SGD:S000000185", "url": "https://alliancegenome.org/gene/SGD:S000000185#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40074-1", "protein_name": "Vacuolar amino acid transporter 6", "gene_name": "AVT6", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVASIRSGVLTLLHTACGAGILAMPYAFKPFGLIPGVIMIVLCGACAMQSLFIQARVAKYVPQGRASFSALTRLINPNLGIVFDLAIAIKCFGVGVSYMIVVGDLMPQIMSVWTRNAWLLNRNVQISLIMLFFVAPLSFLKKLNSLRYASMVAISSVAYLCVLVLLHYVAPSDEILRLKGRISYLLPPQSHDLNVLNTLPIFVFAYTCHHNMFSIINEQRSSRFEHVMKIPLIAISLALILYIAIGCAGYLTFGDNIIGNIIMLYPQAVSSTIGRIAIVLLVMLAFPLQCHPARASIHQILQHFAEENVSISATSADEPTVATESSPLIRDSSLDLNEVIEEESIYQPKETPLRGKSFIVITCSILVASYLVAISVSSLARVLAIVGATGSTSISFILPGLFGYKLIGTEHKTAVPLTTKIFKYTGLLLFIWGLIIMITCLTAALKLN", "length": 448 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-121005-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121005-5#orthology", "database": "AGR" }, { "id": "MGI:2685433", "url": "https://alliancegenome.org/gene/MGI:2685433#orthology", "database": "AGR" }, { "id": "HGNC:32434", "url": "https://alliancegenome.org/gene/HGNC:32434#orthology", "database": "AGR" }, { "id": "RGD:1560237", "url": "https://alliancegenome.org/gene/RGD:1560237#orthology", "database": "AGR" }, { "id": "SGD:S000000921", "url": "https://alliancegenome.org/gene/SGD:S000000921#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P40501-1", "protein_name": "Vacuolar amino acid transporter 7", "gene_name": "AVT7", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MEATSSALSSTANLVKTIVGAGTLAIPYSFKSDGVLVGVILTLLAAVTSGLGLFVLSKCSKTLINPRNSSFFTLCMLTYPTLAPIFDLAMIVQCFGVGLSYLVLIGDLFPGLFGGERNYWIIASAVIIIPLCLVKKLDQLKYSSILGLFALAYISILVFSHFVFELGKGELTNILRNDICWWKIHDFKGLLSTFSIIIFAFTGSMNLFPMINELKDNSMENITFVINNSISLSTALFLIVGLSGYLTFGNETLGNLMLNYDPNSIWIVIGKFCLGSMLILSFPLLFHPLRIAVNNVIIWIEITYGGANPEEDPQVSEYTRASNLRPISMTVEDPAQPSDALDATSYNEQECLLPNGNFDNGSIESQENNNDERGTMAVAGDNEHHAPFVKSRFYWITALLLISMYTLALSVQSFALVLSFVGATGSTSISFTLPGLLGYKLIGLDSLAIGKMIPPKDRFYKRCSLLLVFYGLSVMFLSLYVTVFNRSDEA", "length": 490 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-121005-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121005-5#orthology", "database": "AGR" }, { "id": "MGI:2685433", "url": "https://alliancegenome.org/gene/MGI:2685433#orthology", "database": "AGR" }, { "id": "RGD:1560237", "url": "https://alliancegenome.org/gene/RGD:1560237#orthology", "database": "AGR" }, { "id": "SGD:S000001350", "url": "https://alliancegenome.org/gene/SGD:S000001350#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5HZH7-1", "protein_name": "Solute carrier family 38 member 8", "gene_name": "Slc38a8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEGQPRGSRGPLEKPLPAATHPTLSSLGAVFILLKSALGAGLLNFPWAFYKAGGMLPTFLVALVSLVFLISGLVILGYAASVSGQTTYQGVVRELCGPAMGKLCEICFLTNLLMISVAFLRVIGDQLEKLCDSLLPDAPQPWYAAQNFTLPLISMLVIFPLSALREIALQKYTSILGTLAACYLALVITVQYYLWPQGLIRQPGPLLSPSPWTSVFSVFPTICFGFQCHEAAVSIYCSMWNQSLSHWTLVSVLSLLACCLVYTLTGVYGFLTFGPEVSADILMSYPGNDTAIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWKKSYWATRGPPVLADPSGPWVRLPLTFLWVVVTLTMALFLPDLSEIISIIGGVSSFFIFIFPGLCLICAVDTEPMGPRVKCCLEAWGILSVLVGTFIFGQSTAVAMVELL", "length": 432 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-121005-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121005-5#orthology", "database": "AGR" }, { "id": "MGI:2685433", "url": "https://alliancegenome.org/gene/MGI:2685433#orthology", "database": "AGR" }, { "id": "HGNC:32434", "url": "https://alliancegenome.org/gene/HGNC:32434#orthology", "database": "AGR" }, { "id": "RGD:1560237", "url": "https://alliancegenome.org/gene/RGD:1560237#orthology", "database": "AGR" }, { "id": "SGD:S000000921", "url": "https://alliancegenome.org/gene/SGD:S000000921#orthology", "database": "AGR" }, { "id": "SGD:S000001350", "url": "https://alliancegenome.org/gene/SGD:S000001350#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5SPB1-1", "protein_name": "Sodium-coupled neutral amino acid symporter 2", "gene_name": "slc38a2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNKAPAQMSRFNIAPDMDSSSTNSNEYTNYQDHASKVPLNGIQYSDVEAESQNFLSDHHLGKKKYEAEYSPGSASFGMSVFNLGNAIMGSGILGLSYAMANTGIAMFVILLVAVAIFSLYSVHLLLKTANEGGSLVYEQLGYKAFGIPGKLAASCSITMQNFGAMASYLYIVKYELPIVIRAFLDSNDNAWYTNGDYLVLIVTMSIILPLSLLKNLGYLGYTSGFSLLCMVFFLIVVIYKKFQIPCPLPENFINITVNVSQPPQTNNSTDEECCKPKYFIFNSQTVYAVPILTFAFVCHPAILPMYEELKDRSRRKMQNVANVSFLGMFIMYLLAALFGYLTFNEAVEPELLHTYSKVYNFDVVLLIVRLAVLTAVTLTVPVVLFPIRTSVNHLLGASKEFSWPRHICITVALLVCVNILVIFVPTIRDIFGFIGASAAAMLIFILPSAFYIKLVKKESMKSVQKIGATLFLIMGFLVMTGSMALIIMDWIHNALSSEEHTGGH", "length": 504 }, "evidence": [ { "id": "SGD:S000000185", "url": "https://alliancegenome.org/gene/SGD:S000000185#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6DEL1-1", "protein_name": "Sodium-coupled neutral amino acid transporter 7", "gene_name": "slc38a7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRPDRAINSEAGDWGYSEDAGERAWLLQSPSVDSVQPPSQSDDSRGGTSSLGAVFIVVNAALGAGLLNFPAAFNMAGGITAGVTLQMCMMAFIITGLVILAYCSQVSNESTYQEVVRAVCGKALGVICELAIAVYTFGTCIAFLIIIGDQLDKLIGAINNESEKEISLHWYTDRKFTITLTSVLIILPLSIPKEIGFQKYASTLSVIGTWYVTIIVIVKYIWPSKDVSPGIIPVRPASWTDVFNAMPTICFGFQCHVSSVPVFNSMKKPEIRPWWGVVTISMIICLFVYTGTGVCGFLSFGSSVSQDVLMSYPSDDVAVAIARAFIIICVVTSYPILHFCGRAVLEGLWLRFKGEEVETDVAKERRRRILQTLVWFCLTLILALFIPDIGRVISLIGGLAACFIFVFPGLCLIQAKLSEHDVRSNSWNAMVAYGVIMVTIGAFIFGQTTTNAIYKDIINNPNSP", "length": 465 }, "evidence": [ { "id": "SGD:S000000185", "url": "https://alliancegenome.org/gene/SGD:S000000185#orthology", "database": "AGR" }, { "id": "SGD:S000000921", "url": "https://alliancegenome.org/gene/SGD:S000000921#orthology", "database": "AGR" }, { "id": "SGD:S000001350", "url": "https://alliancegenome.org/gene/SGD:S000001350#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6JWR2-1", "protein_name": "Sodium-coupled neutral amino acid transporter 7", "gene_name": "Slc38a7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQVSINSDYSEWGSSTDAGERARLLQSPCVDVVPKREGEASPGDPDSGTTSTLGAVFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEIAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPDGASGSPWYTDRKFTISLTAFLFILPLSIPKEIGFQKYASSLSVVGTWYVTAIVIIKYIWPDKEMRPGDILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMRQPQVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLRSYPSEDVAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYKGTPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFIFPGLCLIQAKLSEMEEVKPASWWALVSYGVLLVTLGAFIFGQTTANAVFVDLLA", "length": 463 }, "evidence": [ { "id": "SGD:S000000185", "url": "https://alliancegenome.org/gene/SGD:S000000185#orthology", "database": "AGR" }, { "id": "SGD:S000000921", "url": "https://alliancegenome.org/gene/SGD:S000000921#orthology", "database": "AGR" }, { "id": "SGD:S000001350", "url": "https://alliancegenome.org/gene/SGD:S000001350#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BWH0-1", "protein_name": "Sodium-coupled neutral amino acid transporter 7", "gene_name": "Slc38a7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQVSINSDYSEWASSTDAGERARLLQSPCVDVVPKSEGEASPGDPDSGTTSTLGAVFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMSKEPDGASGSPWYTDRKFTISLTAFLFILPLSIPKEIGFQKYASFLSVVGTWYVTAIIIIKYIWPDKEMRPGDILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMRQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLRSYPSEDVAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYKGMPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFIFPGLCLIQAKLSEMEEVKPASWWALVSYGVLLVTLGAFIFGQTTANAIFVDLLA", "length": 463 }, "evidence": [ { "id": "SGD:S000000185", "url": "https://alliancegenome.org/gene/SGD:S000000185#orthology", "database": "AGR" }, { "id": "SGD:S000000921", "url": "https://alliancegenome.org/gene/SGD:S000000921#orthology", "database": "AGR" }, { "id": "SGD:S000001350", "url": "https://alliancegenome.org/gene/SGD:S000001350#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K2P7-1", "protein_name": "Sodium-coupled neutral amino acid symporter 1", "gene_name": "Slc38a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMHFKSGLELTELQNMTVPEDDNVSNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKRKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLILLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKLVIFGATSLQNTGAMLSYLFIVKNELPSAIKSLMGEEDAFSAWYVDGRVLVVMVTFGIILPLCLLKNLGYLGYTSGFSLSCMMFFLIVVIYKKFQTPCMSVEQNSTVSANVTDACTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYEKVQSDLLHKYQSTGDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFHLCRHVLVTIILLIIINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITNQDGDKGTQRIWAALFLGLGVLFSLISIPLVIYDWACSSGTDEGH", "length": 485 }, "evidence": [ { "id": "SGD:S000000185", "url": "https://alliancegenome.org/gene/SGD:S000000185#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q969I6-1", "protein_name": "Sodium-coupled neutral amino acid transporter 4", "gene_name": "SLC38A4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPMELRNVNIEPDDESSSGESAPDSYIGIGNSEKAAMSSQFANEDTESQKFLTNGFLGKKKLADYADEHHPGTTSFGMSSFNLSNAIMGSGILGLSYAMANTGIILFIIMLLAVAILSLYSVHLLLKTAKEGGSLIYEKLGEKAFGWPGKIGAFVSITMQNIGAMSSYLFIIKYELPEVIRAFMGLEENTGEWYLNGNYLIIFVSVGIILPLSLLKNLGYLGYTSGFSLTCMVFFVSVVIYKKFQIPCPLPVLDHSVGNLSFNNTLPMHVVMLPNNSESSDVNFMMDYTHRNPAGLDENQAKGSLHDSGVEYEAHSDDKCEPKYFVFNSRTAYAIPILVFAFVCHPEVLPIYSELKDRSRRKMQTVSNISITGMLVMYLLAALFGYLTFYGEVEDELLHAYSKVYTLDIPLLMVRLAVLVAVTLTVPIVLFPIRTSVITLLFPKRPFSWIRHFLIAAVLIALNNVLVILVPTIKYIFGFIGASSATMLIFILPAVFYLKLVKKETFRSPQKVGALIFLVVGIFFMIGSMALIIIDWIYDPPNSKHH", "length": 547 }, "evidence": [ { "id": "SGD:S000001350", "url": "https://alliancegenome.org/gene/SGD:S000001350#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9H2H9-1", "protein_name": "Sodium-coupled neutral amino acid symporter 1", "gene_name": "SLC38A1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMHFKSGLELTELQNMTVPEDDNISNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKKKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLVLLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKFVIFGATSLQNTGAMLSYLFIVKNELPSAIKFLMGKEETFSAWYVDGRVLVVIVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCIVPELNSTISANSTNADTCTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYDNVQSDLLHKYQSKDDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFNLCRHTVVTCILLVVINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITDQDGDKGTQRIWAALFLGLGVLFSLVSIPLVIYDWACSSSSDEGH", "length": 487 }, "evidence": [ { "id": "SGD:S000000185", "url": "https://alliancegenome.org/gene/SGD:S000000185#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9HBR0-1", "protein_name": "Solute carrier family 38 member 10", "gene_name": "SLC38A10", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAAAASNWGLITNIVNSIVGVSVLTMPFCFKQCGIVLGALLLVFCSWMTHQSCMFLVKSASLSKRRTYAGLAFHAYGKAGKMLVETSMIGLMLGTCIAFYVVIGDLGSNFFARLFGFQVGGTFRMFLLFAVSLCIVLPLSLQRNMMASIQSFSAMALLFYTVFMFVIVLSSLKHGLFSGQWLRRVSYVRWEGVFRCIPIFGMSFACQSQVLPTYDSLDEPSVKTMSSIFASSLNVVTTFYVMVGFFGYVSFTEATAGNVLMHFPSNLVTEMLRVGFMMSVAVGFPMMILPCRQALSTLLCEQQQKDGTFAAGGYMPPLRFKALTLSVVFGTMVGGILIPNVETILGLTGATMGSLICFICPALIYKKIHKNALSSQVVLWVGLGVLVVSTVTTLSVSEEVPEDLAEEAPGGRLGEAEGLMKVEAARLSAQDPVVAVAEDGREKPKLPKEREELEQAQIKGPVDVPGREDGKEAPEEAQLDRPGQGIAVPVGEAHRHEPPVPHDKVVVDEGQDREVPEENKPPSRHAGGKAPGVQGQMAPPLPDSEREKQEPEQGEVGKRPGQAQALEEAGDLPEDPQKVPEADGQPAVQPAKEDLGPGDRGLHPRPQAVLSEQQNGLAVGGGEKAKGGPPPGNAAGDTGQPAEDSDHGGKPPLPAEKPAPGPGLPPEPREQRDVERAGGNQAASQLEEAGRAEMLDHAVLLQVIKEQQVQQKRLLDQQEKLLAVIEEQHKEIHQQRQEDEEDKPRQVEVHQEPGAAVPRGQEAPEGKARETVENLPPLPLDPVLRAPGGRPAPSQDLNQRSLEHSEGPVGRDPAGPPDGGPDTEPRAAQAKLRDGQKDAAPRAAGTVKELPKGPEQVPVPDPAREAGGPEERLAEEFPGQSQDVTGGSQDRKKPGKEVAATGTSILKEANWLVAGPGAETGDPRMKPKQVSRDLGLAADLPGGAEGAAAQPQAVLRQPELRVISDGEQGGQQGHRLDHGGHLEMRKARGGDHVPVSHEQPRGGEDAAVQEPRQRPEPELGLKRAVPGGQRPDNAKPNRDLKLQAGSDLRRRRRDLGPHAEGQLAPRDGVIIGLNPLPDVQVNDLRGALDAQLRQAAGGALQVVHSRQLRQAPGPPEES", "length": 1119 }, "evidence": [ { "id": "SGD:S000001350", "url": "https://alliancegenome.org/gene/SGD:S000001350#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JM15-1", "protein_name": "Sodium-coupled neutral amino acid symporter 1", "gene_name": "Slc38a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMHFKSGLELTELQNMTVPEDDNVSNDSNDFTEVENGQINSKFISDRESRRSLTNSHLEKRKCDEYIPGTTSLGMSVFNLSNAIMGSGILGLAFALANTGILLFLILLTSVTLLSIYSINLLLICSKETGCMVYEKLGEQVFGTTGKLVIFGATSLQNTGAMLSYLFIVKNELPSAIKSLMGEEETFSAWYVDGRVLVVMVTFGIILPLCLLKNLGYLGYTSGFSLSCMVFFLIVVIYKKFQIPCMNGEQNSTVSANVTDACTPKYVTFNSKTVYALPTIAFAFVCHPSVLPIYSELKDRSQKKMQMVSNISFFAMFVMYFLTAIFGYLTFYEKVQSDLLHKYQSTGDILILTVRLAVIVAVILTVPVLFFTVRSSLFELAKKTKFHLCRHVLVTIILLVIINLLVIFIPSMKDIFGVVGVTSANMLIFILPSSLYLKITNQDGDKNTQRIWAALFLALGVLFSLISIPLVIYDWACSSSNGEGH", "length": 485 }, "evidence": [ { "id": "SGD:S000000185", "url": "https://alliancegenome.org/gene/SGD:S000000185#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9NVC3-1", "protein_name": "Sodium-coupled neutral amino acid transporter 7", "gene_name": "SLC38A7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIVVNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVWAVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTISLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPASWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFLTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLSEMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA", "length": 462 }, "evidence": [ { "id": "SGD:S000000185", "url": "https://alliancegenome.org/gene/SGD:S000000185#orthology", "database": "AGR" }, { "id": "SGD:S000000921", "url": "https://alliancegenome.org/gene/SGD:S000000921#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "L-amino acid transmembrane transporter activity", "id": "GO:0015179", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015179", "evidence": [ { "database": "UniProtKB", "id": "A5WVQ9", "url": "https://www.uniprot.org/uniprotkb/A5WVQ9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A5WVQ9", "url": "https://www.uniprot.org/uniprotkb/A5WVQ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "amino acid transmembrane transport", "id": "GO:0003333", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003333", "evidence": [ { "database": "UniProtKB", "id": "A5WVQ9", "url": "https://www.uniprot.org/uniprotkb/A5WVQ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5WVQ9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVQ9" }, { "id": "PF01490", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01490" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amino acid transporter transmembrane", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 434, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 209, "end_pos": 211 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5WVS1-1", "uniprot_ac": "A5WVS1", "uniprot_id": "A5WVS1_DANRE", "mass": { "chemical_mass": 70028.0, "monoisotopic_mass": 70028.0 }, "refseq": { "ac": "NP_001093523", "name": "transmembrane protein 232", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093523" }, "gene_names": [ { "name": "tmem232", "type": "recommended", "evidence": [ { "id": "A5WVS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVS1" } ] }, { "name": "si:dkey-264m17.1", "type": "synonym", "evidence": [ { "id": "NP_001093523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093523" }, { "id": "A5WVS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVS1" } ] }, { "name": "tmem232", "type": "synonym", "evidence": [ { "id": "NP_001093523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093523" } ] } ], "protein_names": [ { "name": "Transmembrane protein 232", "type": "synonym", "evidence": [ { "id": "A5WVS1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WVS1/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 232", "type": "synonym", "evidence": [ { "id": "NP_001093523", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093523" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC128881.1, GFIL01041105.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN18715719 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jun 5, 2025 this sequence version replaced NP_001093523.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001093523", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093523" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WVS1", "url": "https://www.uniprot.org/uniprotkb/A5WVS1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmem232", "url": "https://www.uniprot.org/uniprotkb/A5WVS1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-434", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-434", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000067646", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000067646", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "793774", "url": "https://www.ncbi.nlm.nih.gov/gene/793774", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031747", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031747", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:793774", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793774", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A5WVS1", "url": "https://www.orthodb.org/?gene=A5WVS1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28651", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28651", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28651:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28651:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15877", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15877", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001093523", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093523", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58JL07", "url": "https://www.uniprot.org/uniprotkb/A0AC58JL07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JL07-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JL07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JL14", "url": "https://www.uniprot.org/uniprotkb/A0AC58JL14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JL14-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JL14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JL24", "url": "https://www.uniprot.org/uniprotkb/A0AC58JL24", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JL24-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JL24-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WVS1", "url": "https://www.uniprot.org/uniprotkb/A5WVS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WVS1-1", "url": "https://www.uniprot.org/uniprotkb/A5WVS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-434", "url": "https://zfin.org/ZDB-GENE-070705-434", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPILKIPIKHHLGIVSQSQLEQLIKRHRKKKEETGNVTARKKIKRNPLETTEDFIEKYNQVQGSKEQEKYENLAKEFLCRWKRLAGFTAAAGKGKHVDLPRAWTQLVLLSLSNGNVRNDSLNALVVSLDHAPFNADQIPVLFHLVESVQHFLCSNTTLSEQPCSYEKKMLQLGYLVSLRLFIFQLTGMNEQELSNIYLQRLKELLTCETRYQEFPDMLFAVQLMLCVWEVLCGLRLTEDNAAQVSVEARELGVNQVLRQCLLSYHCVQNNGTQLPQVIKQLMLLRDKLQHDNWVECGLGLMILGEAAKSSMLCLQALMNLHMTQRQETESQTASWPWQLEHIYCSILINICQNSHCTEIRKTALNGKSISSTRRCSGGLITLLKQLHEDKWRLRYTVIQGLVQISQKITLQEDLRNTAWSALQKHLNQETKPCVINAATIIEGDKRLLEKHRERIRSSRTDNACVCAVSEQITRRLAHALSKICPPVQLSACSADHRHRVKPSQLTAWAGRRQTEPNTPHIFTKDTFKTPRHGQRGAFHMDLRTRTDLDLIKVVEDQWQKELKIREREEEMEKTELELRKEEEEEKIIQKRMEKVKKNTKPYELQ", "length": 605, "header": "tr|A5WVS1-1|A5WVS1_DANRE Isoform 1 of Transmembrane protein 232 OS=Danio rerio OX=7955 GN=tmem232 PE=4 SV=1 CANONICAL=A5WVS1-1" }, "isoforms": [ { "isoform_ac": "A0AC58JL07-1", "url": "https://www.uniprot.org/uniprotkb/A5WVS1/entry#A0AC58JL07-1", "sequence": { "sequence": "MLVQEKKSNEIPLKQQKTLLKNTIKYKLLAGFTAAAGEGKHVDLPRAWTQLLLLSLSNGNVRNDSLNVLVVSLDHAPFNADQIPVLFHLVESVQHFLCSNTTLSEQPCSYEKKMLQLGYLVSLRLFIFQLTGMNEQELSNIYLQKLKELLTCETRYQEFPDMLFAVQLMLCVWEVLCGLRLTEDNAAQVSVEARELGVNQVLRQCLLSYHCVQNNGTQLPQVIKQLMLLRDKLQHDNWVECGLGLMILGEAAKSSMLCLQALMNLHMTQRQETESQTASWPWQLEHIYCSILINICQNSHCTEIRKTALNGKSISSTRRCSGGLITLLKQLHEDKWRLRYTVVQGLVQISQKITLQEDLRNTAWSALQKHLNQETKPCVVNAATIIEGDKRLLEKHRERIRSSRNDNACVCAVSEQITRRLAHALSKICPPVQLSACSADHRHRVKPPQLTAWAGRRQTEPNTPHIFTKDTFKTPRHGQRGAFHMDLRTRTDLDLIKVVEDQWQKELKIREREEEMEKTELELRKEDEEEKIIQKRMEKVKKNTKPYELQ", "length": 550, "header": "tr|A0AC58JL07-1|A0AC58JL07_DANRE Computationally mapped isoform of Transmembrane protein 232 isoform X1 OS=Danio rerio OX=7955 GN=tmem232 PE=4 SV=1 CANONICAL=A5WVS1-1" }, "locus": {} }, { "isoform_ac": "A0AC58JL14-1", "url": "https://www.uniprot.org/uniprotkb/A5WVS1/entry#A0AC58JL14-1", "sequence": { "sequence": "MEDSLNVLVVSLDHAPFNADQIPVLFHLVESVQHFLCSNTTLSEQPCSYEKKMLQLGYLVSLRLFIFQLTGMNEQELSNIYLQKLKELLTCETRYQEFPDMLFAVQLMLCVWEVLCGLRLTEDNAAQVSVEARELGVNQVLRQCLLSYHCVQNNGTQLPQVIKQLMLLRDKLQHDNWVECGLGLMILGEAAKSSMLCLQALMNLHMTQRQETESQTASWPWQLEHIYCSILINICQNSHCTEIRKTALNGKSISSTRRCSGGLITLLKQLHEDKWRLRYTVVQGLVQISQKITLQEDLRNTAWSALQKHLNQETKPCVVNAATIIEGDKRLLEKHRERIRSSRNDNACVCAVSEQITRRLAHALSKICPPVQLSACSADHRHRVKPPQLTAWAGRRQTEPNTPHIFTKDTFKTPRHGQRGAFHMDLRTRTDLDLIKVVEDQWQKELKIREREEEMEKTELELRKEDEEEKIIQKRMEKVKKNTKPYELQ", "length": 489, "header": "tr|A0AC58JL14-1|A0AC58JL14_DANRE Computationally mapped isoform of Transmembrane protein 232 isoform X2 OS=Danio rerio OX=7955 GN=tmem232 PE=4 SV=1 CANONICAL=A5WVS1-1" }, "locus": {} }, { "isoform_ac": "A0AC58JL24-1", "url": "https://www.uniprot.org/uniprotkb/A5WVS1/entry#A0AC58JL24-1", "sequence": { "sequence": "MMFQSWWNHWNAYKLYSCLYLLTELLTCETRYQEFPDMLFAVQLMLCVWEVLCGLRLTEDNAAQVSVEARELGVNQVLRQCLLSYHCVQNNGTQLPQVIKQLMLLRDKLQHDNWVECGLGLMILGEAAKSSMLCLQALMNLHMTQRQETESQTASWPWQLEHIYCSILINICQNSHCTEIRKTALNGKSISSTRRCSGGLITLLKQLHEDKWRLRYTVVQGLVQISQKITLQEDLRNTAWSALQKHLNQETKPCVVNAATIIEGDKRLLEKHRERIRSSRNDNACVCAVSEQITRRLAHALSKICPPVQLSACSADHRHRVKPPQLTAWAGRRQTEPNTPHIFTKDTFKTPRHGQRGAFHMDLRTRTDLDLIKVVEDQWQKELKIREREEEMEKTELELRKEDEEEKIIQKRMEKVKKNTKPYELQ", "length": 426, "header": "tr|A0AC58JL24-1|A0AC58JL24_DANRE Computationally mapped isoform of Transmembrane protein 232 isoform X3 OS=Danio rerio OX=7955 GN=tmem232 PE=4 SV=1 CANONICAL=A5WVS1-1" }, "locus": {} }, { "isoform_ac": "A5WVS1-1", "url": "https://www.uniprot.org/uniprotkb/A5WVS1/entry#A5WVS1-1", "sequence": { "sequence": "MPILKIPIKHHLGIVSQSQLEQLIKRHRKKKEETGNVTARKKIKRNPLETTEDFIEKYNQVQGSKEQEKYENLAKEFLCRWKRLAGFTAAAGKGKHVDLPRAWTQLVLLSLSNGNVRNDSLNALVVSLDHAPFNADQIPVLFHLVESVQHFLCSNTTLSEQPCSYEKKMLQLGYLVSLRLFIFQLTGMNEQELSNIYLQRLKELLTCETRYQEFPDMLFAVQLMLCVWEVLCGLRLTEDNAAQVSVEARELGVNQVLRQCLLSYHCVQNNGTQLPQVIKQLMLLRDKLQHDNWVECGLGLMILGEAAKSSMLCLQALMNLHMTQRQETESQTASWPWQLEHIYCSILINICQNSHCTEIRKTALNGKSISSTRRCSGGLITLLKQLHEDKWRLRYTVIQGLVQISQKITLQEDLRNTAWSALQKHLNQETKPCVINAATIIEGDKRLLEKHRERIRSSRTDNACVCAVSEQITRRLAHALSKICPPVQLSACSADHRHRVKPSQLTAWAGRRQTEPNTPHIFTKDTFKTPRHGQRGAFHMDLRTRTDLDLIKVVEDQWQKELKIREREEEMEKTELELRKEEEEEKIIQKRMEKVKKNTKPYELQ", "length": 605, "header": "tr|A5WVS1-1|A5WVS1_DANRE Isoform 1 of Transmembrane protein 232 OS=Danio rerio OX=7955 GN=tmem232 PE=4 SV=1 CANONICAL=A5WVS1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A5WVS1", "url": "https://www.uniprot.org/uniprotkb/A5WVS1" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:793774", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793774", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B1WBT0-1", "protein_name": "Transmembrane protein 232", "gene_name": "Tmem232", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKKWPSFSVTKEFILRFNNTDNRVKEEELLEQARKFTVRCKRKLGLKTLGSGKHVHLPTAWAEVIYLAQCKGEIQDEALNMLYASLDHVSFDCDQLPTLFFLAESVLYRLCCDAFKKEYLYSVEIKLVKIGYLIFLRLFVFFLHGHLENFKQHLLRLQPYLYALYYSEPSYYKYPNILSSLQFILKTAEIICKRELHFEVFESLREVEDPFSDTNHVQLNKRGYEVNHLLWHSVAAWSCVQDNRPQLNAVLDHILFHKAQLQTKCWLDSALALLVLGEAAKLNMACLKTLMDLMTHFLLSPQSQEDYCSIYDIPWASDIVFIYTSIIAEVCLYAATSDLRKTALIGFCVCKDPQQDIHLTNKSEEMPELDGASILTLLKYFSSRISDNCAKVIWVGYYGIVYNLVKMSWELQGDEEQDGFRNMVWQTLQKIKDYEEDPRIQNAVTIAQAELNDAADPFSSKAAPNSEAFSKYIGWRIANTLSRLFFPSLDVSALPQKTPVETDLQRKHTISKRQPEKKGVVRIVMKEHPSVLELSMFPYPDFFTKADKKLEEVIDHHWQKDMETLKQIEAVCEAQNRKDEEEKEKIRFQEIMKQRERKLNKQTKPYEITPSEKKE", "length": 617 }, "evidence": [ { "id": "MGI:2685786", "url": "https://alliancegenome.org/gene/MGI:2685786#orthology", "database": "AGR" }, { "id": "HGNC:37270", "url": "https://alliancegenome.org/gene/HGNC:37270#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "C9JQI7-1", "protein_name": "Transmembrane protein 232", "gene_name": "TMEM232", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNMPVNKSPMINTCGGISSPYHEELWKLNFQHLSGERGHKSRPTFSITKEFILRFNQTQNSKEKEELLELARKIILRCKRKLGLKTLGSGRHVHLPAAWTEVIYLAQCKGEIQDESLNMLYASLDHASFDYDHLPALFFVAESVLYRLCCDASLKTYLYSVEIKLAKIGYLVFLRLFIFFLHGHLESFKQHLLRLQPYLYALSFSGASYHKYPNIFSNVQFILKASEIIGKRELRSESIFRPVEDKKRYENTDSDMGGYEINHLLWHCVAAWSCVQNNSPQLNNVLEHLVFHKTQLQKKCWLDSVLALLVLGEAAKLNMACLKALMDVVRDFVSSIMSVQNQEESCKVDDFSWAWNVVYIYTVILAEICLYAATSDLRKTALIGFCHCKSSQKNILYLDKSVPPELKETSILSLLEYFSSKMSENCDQVVWTGYYGLVYNLVKISWELQGDEEQDGLRNMIWQTLQKTKDYEEDVRIQNAINIAQAELNDPTDPFTRYSTNISSNVGEEVFSKYIGWRIANTLSKLFFPPIEAHFLPLKKPSIKKDQTKYPNKKLESVKKQVLHFTVREHPSVSEIPMFPYPDFFTKADKELAKIIDHHWQEELKIREKEDAICKAQELKDKKLAEKNHFQEVMKKREEKLHKQTKPYELPYRKEVI", "length": 657 }, "evidence": [ { "id": "MGI:2685786", "url": "https://alliancegenome.org/gene/MGI:2685786#orthology", "database": "AGR" }, { "id": "HGNC:37270", "url": "https://alliancegenome.org/gene/HGNC:37270#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-434", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-434#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5K6N0-1", "protein_name": "Transmembrane protein 232", "gene_name": "Tmem232", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKAYKPPVVNKFGVISSTYHEELLKSIFESSNRRKSQKPKPSFSISKEFILRFNHTDNPAEEEELLEQARRLIVRSKRKLGLKTLGSGKHVHLPTAWAEVIYLAQCKGEIQDEALNMLHASLDHVSFDHDQLPALFFLAESVLYRLCCDAFMKGYLYSVEIKLVKIGYLIFLRLFVFFLHGHLESFKQHLLRLQPYLYALHFSEPSYYKYPNIISNVQFILKTSEIICKRELHSEPFVESPDETEDPYSDLNHLQLNKRGYEVNHLLWHSVAAWSCVQNNRPQLTEVLEHLLFYKTQLQTKCWLDSALALMVLGEAAKLDMACLKTLMDLVTDFLENILSAQNQEENYNIYDTSWASEIVFTYTTIIAEVCLYAATSDLRKTALIGFCACKSPQQGISLTDKSEELPELDGASILTLLKYFSSRISDNCEKVIWIGYYGIVYNLVKMSWELQGEQDQDGLRNMIWQTLQKIKDYEQDPRIRCALVIAQAELNGPSDPFCTKATPNSGEEVFSKYIGWRIATTLSRLFFPSLDVAPPKTPVEVDLPRKHTIRERQPAKKRVLRFILKDHSSVVEVSMTPYPNFFTKADKKLEEIIDHHWQKDMEARKREEEAYKAQNQKDKEEKEKIHFQEIMKQRERKLNKQTKPYEIILSEKESGSEKKCGFFELKPSTAPNAK", "length": 675 }, "evidence": [ { "id": "MGI:2685786", "url": "https://alliancegenome.org/gene/MGI:2685786#orthology", "database": "AGR" }, { "id": "HGNC:37270", "url": "https://alliancegenome.org/gene/HGNC:37270#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-434", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-434#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 270, "end_pos": 272, "annotation": "n_glycosylation_sequon" }, { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 155, "end_pos": 157 }, { "start_pos": 270, "end_pos": 272 }, { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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[ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1 and EH506688.1. On May 20, 2010 this sequence version replaced XP_001919123.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001166132", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001166132" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WW23", "url": "https://www.uniprot.org/uniprotkb/A5WW23" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "serf2a", "url": "https://www.uniprot.org/uniprotkb/A5WW23", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-180", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-180", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000075881", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000075881", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100149345", "url": "https://www.ncbi.nlm.nih.gov/gene/100149345", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007513", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007513", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040211", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040211", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100149345", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100149345", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NQQEFTH", "url": "https://omabrowser.org/oma/group/NQQEFTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5WW23", "url": "https://www.orthodb.org/?gene=A5WW23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13596", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13596", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13596:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13596:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04419", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04419", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001166132", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001166132", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5WW23", "url": "https://www.uniprot.org/uniprotkb/A5WW23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WW23-1", "url": "https://www.uniprot.org/uniprotkb/A5WW23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-180", "url": "https://zfin.org/ZDB-GENE-070705-180", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTRGNQRELARQKNVKKHSDMQKGKRNDDGLSAAARKQRDAEIMQQKQKKAHEKGDSKAKQ", "length": 61, "header": "tr|A5WW23-1|A5WW23_DANRE Isoform 1 of Uncharacterized protein LOC100149345 OS=Danio rerio OX=7955 GN=serf2a PE=3 SV=1 CANONICAL=A5WW23-1" }, "isoforms": [ { "isoform_ac": "A5WW23-1", "url": "https://www.uniprot.org/uniprotkb/A5WW23/entry#A5WW23-1", "sequence": { "sequence": "MTRGNQRELARQKNVKKHSDMQKGKRNDDGLSAAARKQRDAEIMQQKQKKAHEKGDSKAKQ", "length": 61, "header": "tr|A5WW23-1|A5WW23_DANRE Isoform 1 of Uncharacterized protein LOC100149345 OS=Danio rerio OX=7955 GN=serf2a PE=3 SV=1 CANONICAL=A5WW23-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A5WW23", "url": "https://www.uniprot.org/uniprotkb/A5WW23" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A5WW23", "url": "https://www.uniprot.org/uniprotkb/A5WW23" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100149345", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100149345", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GM20-1", "protein_name": "Small EDRK-rich factor 2", "gene_name": "Serf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQSAPSSLPPGTRRSCSRSRKRQTRRRRNPSSFVASCPTLLPYACVPGASPTMLEFLPVVLTGPSTDGIPFALSLQRVPFVLPSPQVASLPLGHSWG", "length": 133 }, "evidence": [ { "id": "HGNC:10757", "url": "https://alliancegenome.org/gene/HGNC:10757#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1Q4L4-1", "protein_name": "Small EDRK-rich factor 2", "gene_name": "serf2b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTRGNQRELARQKNAKKQTDSSKGKRNEDGLSAAARKQRDAEIMQQKQKKANEKPEPKGK", "length": 60 }, "evidence": [ { "id": "MGI:1337041", "url": "https://alliancegenome.org/gene/MGI:1337041#orthology", "database": "AGR" }, { "id": "HGNC:10757", "url": "https://alliancegenome.org/gene/HGNC:10757#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P84101-1", "protein_name": "Small EDRK-rich factor 2", "gene_name": "SERF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQRDSEIMQQKQKKANEKKEEPK", "length": 59 }, "evidence": [ { "id": "MGI:1337041", "url": "https://alliancegenome.org/gene/MGI:1337041#orthology", "database": "AGR" }, { "id": "HGNC:10757", "url": "https://alliancegenome.org/gene/HGNC:10757#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-180", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-180#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P84102-1", "protein_name": "Small EDRK-rich factor 2", "gene_name": "Serf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTRGNQRELARQKNMKKQSDSVKGKRRDDGLSAAARKQRDSEIMQQKQKKANEKKEEPK", "length": 59 }, "evidence": [ { "id": "MGI:1337041", "url": "https://alliancegenome.org/gene/MGI:1337041#orthology", "database": "AGR" }, { "id": "HGNC:10757", "url": "https://alliancegenome.org/gene/HGNC:10757#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-180", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-180#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q3E7B7-1", "protein_name": "SERF-like protein YDL085C-A", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces 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"pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5WW23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WW23" }, { "id": "PF04419", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04419" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small EDRK-rich factor-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 37, "start_aa": "Met", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, 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"publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5WW28-1", "uniprot_ac": "A5WW28", "uniprot_id": "A5WW28_DANRE", "mass": { "chemical_mass": 9228.0, "monoisotopic_mass": 9228.0 }, "refseq": { "ac": "NP_001269112", "name": "protein S100-A11", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269112" }, "gene_names": [ { "name": "s100a11", "type": "recommended", "evidence": [ { "id": "A5WW28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ] }, { "name": "s100a11", "type": "synonym", "evidence": [ { "id": "NP_001269112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269112" } ] }, { "name": "si:dkey-105n5.1", "type": "synonym", "evidence": [ { "id": "NP_001269112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269112" }, { "id": "A5WW28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ] } ], "protein_names": [ { "name": "Protein S100-A11", "type": "synonym", "evidence": [ { "id": "A5WW28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WW28/entry#names_and_taxonomy" } ] }, { "name": "protein S100-A11", "type": "synonym", "evidence": [ { "id": "NP_001269112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269112" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH537929.1, EH587932.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB769550.1 and EH537929.1. On Aug 22, 2013 this sequence version replaced XP_002665526.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001269112", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269112" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "s100a11", "url": "https://www.uniprot.org/uniprotkb/A5WW28", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070717-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070717-5", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000093628", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000093628", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00213", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00213", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100307070", "url": "https://www.ncbi.nlm.nih.gov/gene/100307070", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013787", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013787", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034325", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034325", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100307070", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100307070", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQEFWQL", "url": "https://omabrowser.org/oma/group/FQEFWQL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5WW28", "url": "https://www.orthodb.org/?gene=A5WW28", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11639:SF130", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11639:SF130", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001269112", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001269112", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WW28-1", "url": "https://www.uniprot.org/uniprotkb/A5WW28-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070717-5", "url": "https://zfin.org/ZDB-GENE-070717-5", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MESAINVLVSEFKAYAGKEGSASTLSKEEFTSLVKSQLPNFVKNSSDPATIDHLMSSLDANNDGQLTFMEFWNLIGNVANKHGGF", "length": 85, "header": "tr|A5WW28-1|A5WW28_DANRE Isoform 1 of Protein S100-A11 OS=Danio rerio OX=7955 GN=s100a11 PE=1 SV=1 CANONICAL=A5WW28-1" }, "isoforms": [ { "isoform_ac": "A5WW28-1", "url": "https://www.uniprot.org/uniprotkb/A5WW28/entry#A5WW28-1", "sequence": { "sequence": "MESAINVLVSEFKAYAGKEGSASTLSKEEFTSLVKSQLPNFVKNSSDPATIDHLMSSLDANNDGQLTFMEFWNLIGNVANKHGGF", "length": 85, "header": "tr|A5WW28-1|A5WW28_DANRE Isoform 1 of Protein S100-A11 OS=Danio rerio OX=7955 GN=s100a11 PE=1 SV=1 CANONICAL=A5WW28-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Structural and functional diversification in the teleost S100 family of calcium-binding proteins.", "journal": "BMC Evol. Biol.", "date": "2008", "authors": "Kraemer Andreas M, Saraiva Luis R, Korsching Sigrun I", "evidence": [ { "database": "UniProtKB", "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ], "reference": [ { "type": "PubMed", "id": "18275604", "url": "https://glygen.org/publication/PubMed/18275604" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Possible molecular mechanism underlying cadmium-induced circadian rhythms disruption in zebrafish.", "journal": "Biochem. Biophys. Res. Commun.", "date": "2016", "authors": "Xiao Bo, Chen Tian-Ming, Zhong Yingbin", "evidence": [ { "database": "UniProtKB", "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ], "reference": [ { "type": "PubMed", "id": "27784643", "url": "https://glygen.org/publication/PubMed/27784643" } ] }, { "title": "Metabolic disruption of zebrafish (Danio rerio) embryos by bisphenol A. An integrated metabolomic and transcriptomic approach.", "journal": "Environ. Pollut.", "date": "2017", "authors": "Ortiz-Villanueva Elena, Navarro-Mart\u00edn Laia, Jaumot Joaquim, Benavente Fernando, Sanz-Nebot Victoria, Pi\u00f1a Benjam\u00edn, Tauler Rom\u00e0", "evidence": [ { "database": "UniProtKB", "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ], "reference": [ { "type": "PubMed", "id": "28780062", "url": "https://glygen.org/publication/PubMed/28780062" } ] }, { "title": "Transcriptomic responses of S100 family to bacterial and viral infection in zebrafish.", "journal": "Fish Shellfish Immunol.", "date": "2019", "authors": "Zhang Chang, Zhang Qin, Wang Junya, Tian Jiayin, Song Yunjie, Xie Haixia, Chang Mingxian, Nie Pin, Gao Qian, Zou Jun", "evidence": [ { "database": "UniProtKB", "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ], "reference": [ { "type": "PubMed", "id": "31546038", "url": "https://glygen.org/publication/PubMed/31546038" } ] }, { "title": "Multiple Developmental Defects in sox11a Mutant Zebrafish with Features of Coffin-Siris Syndrome.", "journal": "Int. J. Biol. Sci.", "date": "2020", "authors": "Jia Shaoting, Wu Xingxing, Wu Yunya, Cui Xuefan, Tao Binbin, Zhu Zuoyan, Hu Wei", "evidence": [ { "database": "UniProtKB", "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ], "reference": [ { "type": "PubMed", "id": "33061816", "url": "https://glygen.org/publication/PubMed/33061816" } ] } ], "pathway": [ { "id": "dre:100307070", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100307070", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LKR4-1", "protein_name": "Protein S100", "gene_name": "", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "VAKLSNPTETEVNRRCIKSLIAVFQKHAGRDGNNSKLSKAESLIFMNTELGAFTKNPKDCGVLDHMMKKLDLNSDGQLDFQEFLNLIGGLVIACHESFLKSVSCQK", "length": 106 }, "evidence": [ { "id": "A5WW28", "url": "https://omabrowser.org/oma/group/A5WW28/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8I6GFF5-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "LOC100362296", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETERCIESLIALFQKYNGKDKNSCQLSKTEFLSFMNTELATIRKNQKDPSVFDCMMNKLDLNSDGHLDSQEFPNLIGGLAIACHESFLQTSKKNI", "length": 98 }, "evidence": [ { "id": "MGI:1338798", "url": "https://alliancegenome.org/gene/MGI:1338798#orthology", "database": "AGR" }, { "id": "HGNC:10488", "url": "https://alliancegenome.org/gene/HGNC:10488#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LYQ0-1", "protein_name": "Protein S100", "gene_name": "S100a11l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESLIAVFQKYTGKDGNSCQFYKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLIGGLAIACHESFLQTSQKRI", "length": 90 }, "evidence": [ { "id": "MGI:1338798", "url": "https://alliancegenome.org/gene/MGI:1338798#orthology", "database": "AGR" }, { "id": "HGNC:10488", "url": "https://alliancegenome.org/gene/HGNC:10488#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1M053-1", "protein_name": "EF-hand domain-containing protein", "gene_name": "LOC100359550", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALLIRAQTEAPVPDTVSRSRSPASLLNLAKMPTETERCIEFLLAVFQMHCGKGRNSRQLSKTEFLPFMNTEMAPFTKNPKDPGVLDRGMKQLDRNSDGRLDFQEFLNLIGGLAMACHESFLGSSGSKQKCFSMVSGKARYENGIYIHMLKTI", "length": 154 }, "evidence": [ { "id": "MGI:1338798", "url": "https://alliancegenome.org/gene/MGI:1338798#orthology", "database": "AGR" }, { "id": "HGNC:10488", "url": "https://alliancegenome.org/gene/HGNC:10488#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P31949-1", "protein_name": "Protein S100-A11", "gene_name": "S100A11", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKISSPTETERCIESLIAVFQKYAGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDGQLDFSEFLNLIGGLAMACHDSFLKAVPSQKRT", "length": 105 }, "evidence": [ { "id": "MGI:1338798", "url": "https://alliancegenome.org/gene/MGI:1338798#orthology", "database": "AGR" }, { "id": "HGNC:10488", "url": "https://alliancegenome.org/gene/HGNC:10488#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070717-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070717-5#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50543-1", "protein_name": "Protein S100-A11", "gene_name": "S100a11", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTETERCIESLIAVFQKYSGKDGNNTQLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNCDGQLDFQEFLNLIGGLAIACHDSFIQTSQKRI", "length": 98 }, "evidence": [ { "id": "MGI:1338798", "url": "https://alliancegenome.org/gene/MGI:1338798#orthology", "database": "AGR" }, { "id": "HGNC:10488", "url": "https://alliancegenome.org/gene/HGNC:10488#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070717-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070717-5#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6B345-1", "protein_name": "Protein S100-A11", "gene_name": "S100a11", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTETERCIESLIAVFQKYSGKDGNSCHLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDLNSDGQLDFQEFLNLIGGLAIACHESFLQTSQKRI", "length": 98 }, "evidence": [ { "id": "MGI:1338798", "url": "https://alliancegenome.org/gene/MGI:1338798#orthology", "database": "AGR" }, { "id": "HGNC:10488", "url": "https://alliancegenome.org/gene/HGNC:10488#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ], "pmid": "" }, { "name": "perinuclear region of cytoplasm", "id": "GO:0048471", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048471", "evidence": [ { "database": "UniProtKB", "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "transition metal ion binding", "id": "GO:0046914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046914", "evidence": [ { "database": "UniProtKB", "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ], "pmid": "" }, { "name": "calcium-dependent protein binding", "id": "GO:0048306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048306", "evidence": [ { "database": "UniProtKB", "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "A5WW28", "url": "https://www.uniprot.org/uniprotkb/A5WW28" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A5WW28", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WW28" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 81, "start_aa": "Ser", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 44, "end_pos": 46 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A5WWK4-1", "uniprot_ac": "A5WWK4", "uniprot_id": "A5WWK4_DANRE", "mass": { "chemical_mass": 11609.0, "monoisotopic_mass": 11609.0 }, "refseq": { "ac": "NP_001092899", "name": "protein FAM163A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092899" }, "gene_names": [ { "name": "fam163ab", "type": "recommended", "evidence": [ { "id": "A5WWK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WWK4" } ] }, { "name": "fam163ab", "type": "synonym", "evidence": [ { "id": "NP_001092899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092899" } ] }, { "name": "si:dkey-171o17.8", "type": "synonym", "evidence": [ { "id": "NP_001092899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092899" }, { "id": "A5WWK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WWK4" } ] } ], "protein_names": [ { "name": "Protein FAM163A", "type": "synonym", "evidence": [ { "id": "A5WWK4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A5WWK4/entry#names_and_taxonomy" } ] }, { "name": "chromosome 1 open reading frame 76-like", "type": "synonym", "evidence": [ { "id": "NP_001092899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092899" } ] }, { "name": "protein FAM163A", "type": "synonym", "evidence": [ { "id": "NP_001092899", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092899" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC142810.1, GDQH01036665.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000022.1. On Jul 5, 2007 this sequence version replaced XP_001344120.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001092899", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092899" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A5WWK4", "url": "https://www.uniprot.org/uniprotkb/A5WWK4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam163ab", "url": "https://www.uniprot.org/uniprotkb/A5WWK4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-312", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-312", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000093021", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000093021", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100004942", "url": "https://www.ncbi.nlm.nih.gov/gene/100004942", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100004942", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004942", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CGQPCGV", "url": "https://omabrowser.org/oma/group/CGQPCGV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A5WWK4", "url": "https://www.orthodb.org/?gene=A5WWK4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31914", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31914", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31914:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31914:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001092899", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001092899", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A5WWK4", "url": "https://www.uniprot.org/uniprotkb/A5WWK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A5WWK4-1", "url": "https://www.uniprot.org/uniprotkb/A5WWK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-312", "url": "https://zfin.org/ZDB-GENE-070705-312", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTAGTVVITGGILAAVILLCIIVVLCYCRLQYYCCKKHGSDPDAVCPQPQLSYGVDGMVCAPLSPSPDSNFCPSCSPYSSTFYIHNGGERLIYLPSQYSNTRAMSTDV", "length": 108, "header": "tr|A5WWK4-1|A5WWK4_DANRE Isoform 1 of Protein FAM163A OS=Danio rerio OX=7955 GN=fam163ab PE=3 SV=1 CANONICAL=A5WWK4-1" }, "isoforms": [ { "isoform_ac": "A5WWK4-1", "url": "https://www.uniprot.org/uniprotkb/A5WWK4/entry#A5WWK4-1", "sequence": { "sequence": "MTAGTVVITGGILAAVILLCIIVVLCYCRLQYYCCKKHGSDPDAVCPQPQLSYGVDGMVCAPLSPSPDSNFCPSCSPYSSTFYIHNGGERLIYLPSQYSNTRAMSTDV", "length": 108, "header": "tr|A5WWK4-1|A5WWK4_DANRE Isoform 1 of Protein FAM163A OS=Danio rerio OX=7955 GN=fam163ab PE=3 SV=1 CANONICAL=A5WWK4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2002", "authors": "Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA", "evidence": [ { "database": "UniProtKB", "id": "A5WWK4", "url": "https://www.uniprot.org/uniprotkb/A5WWK4" } ], "reference": [ { "type": "PubMed", "id": "12477932", "url": "https://glygen.org/publication/PubMed/12477932" } ] } ], "pathway": [ { "id": "dre:100004942", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004942", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AIB4-1", "protein_name": "Family with sequence similarity 163 member A", "gene_name": "FAM163A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKSRAEDADDEEEEHDLPTHPRGPPCNACSSQALDGQGGLAPLPSEPCGQPCGVAASHCTTCSPYSSPFYIRTADMVPNGGGGERLPFAPTYYKEGGPPSLKVAAPQSYPVTWPGSGREAFTNPRAISTDV", "length": 166 }, "evidence": [ { "id": "A5WWK4", "url": "https://omabrowser.org/oma/group/A5WWK4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0AAA9SU95-1", "protein_name": "Family with sequence similarity 163 member A", "gene_name": "FAM163A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKSRAEDADEEGEEEHDLPTHPRGPACNACSSQALDGRGSLAPVPGEPCGQPCRVAAGHCTACSPYSSPFYIRTADMVPNGGGGERLSFAPTYYKEGGPPSLQVAAPQSYPVTWPGSGREAFTNPRAISTDV", "length": 167 }, "evidence": [ { "id": "A5WWK4", "url": "https://omabrowser.org/oma/group/A5WWK4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "B0S6B8-1", "protein_name": "Protein FAM163A", "gene_name": "fam163aa", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKRNESEGEAGSVGDPQPQFACNAYSAPGVDGAAVTPLSLPYDPAQPHSYCPTCSPYYLRSSDEMRNGGERLSYMPTHYENHGATALGLAAMYGPVLSHRSTPDFYTNTRAISTDV", "length": 150 }, "evidence": [ { "id": "MGI:3618859", "url": "https://alliancegenome.org/gene/MGI:3618859#orthology", "database": "AGR" }, { "id": "HGNC:28274", "url": "https://alliancegenome.org/gene/HGNC:28274#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZIK4-1", "protein_name": "Family with sequence similarity 163, member A", "gene_name": "Fam163a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKGTDDEEAEEEEEAEEHDLSLHPRAPTCNACSSQVLDGRGSLAPLTSESCSQPCGVASHCTTCSPYRTPFYIRTADMVPNGGGGERLSFAPTYYKEGGTPSLKLAAPQSYPVTWPSSGHEAFTNPRAISTDV", "length": 168 }, "evidence": [ { "id": "MGI:3618859", "url": "https://alliancegenome.org/gene/MGI:3618859#orthology", "database": "AGR" }, { "id": "HGNC:28274", "url": "https://alliancegenome.org/gene/HGNC:28274#orthology", "database": "AGR" }, { "id": "A5WWK4", "url": "https://omabrowser.org/oma/group/A5WWK4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BS52-1", "protein_name": "Family with sequence similarity 163 member A", "gene_name": "FAM163A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKDDPNEEEEEEEEEEEESDLPTHSHPGTCNACSSRMADGQGSPTPIPELNQHGAHPRCPTCSPYGSPFYIRTPDMVRNGGERVAYAPACYPEMGPPVGLQGFPLSRHGLREGFPPSRAISTEV", "length": 159 }, "evidence": [ { "id": "A5WWK4", "url": "https://omabrowser.org/oma/group/A5WWK4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q8CAA5-1", "protein_name": "Protein FAM163A", "gene_name": "Fam163a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKGTDGEDAEEEEEEEEHGLSIHPRVPACNACSSHVLDGRGGLAPLTSESCSQPCGVASHCTTCSPYRTPFYIRTADMVPNGGGGERLSFAPTHYKEGGTPSLKLAAPQNYPVTWPSSGHEAFTNPRAISTDV", "length": 168 }, "evidence": [ { "id": "MGI:3618859", "url": "https://alliancegenome.org/gene/MGI:3618859#orthology", "database": "AGR" }, { "id": "HGNC:28274", "url": "https://alliancegenome.org/gene/HGNC:28274#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-312", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-312#orthology", "database": "AGR" }, { "id": "A5WWK4", "url": "https://omabrowser.org/oma/group/A5WWK4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96GL9-1", "protein_name": "Protein FAM163A", "gene_name": "FAM163A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKSGTEVADEEEEREHDLPTHPRGPTCNACSSQALDGRGSLAPLTSEPCSQPCGVAASHCTTCSPYSSPFYIRTADMVPNGGGGERLSFAPTYYKEGGPPSLKLAAPQSYPVTWPGSGREAFTNPRAISTDV", "length": 167 }, "evidence": [ { "id": "MGI:3618859", "url": "https://alliancegenome.org/gene/MGI:3618859#orthology", "database": "AGR" }, { "id": "HGNC:28274", "url": "https://alliancegenome.org/gene/HGNC:28274#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-312", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-312#orthology", "database": "AGR" }, { "id": "A5WWK4", "url": "https://omabrowser.org/oma/group/A5WWK4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A5WWK4", "url": "https://www.uniprot.org/uniprotkb/A5WWK4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A8DZ56-1", "uniprot_ac": "A8DZ56", "uniprot_id": "A8DZ56_DANRE", "mass": { "chemical_mass": 28931.0, "monoisotopic_mass": 28931.0 }, "refseq": { "ac": "NP_001013505", "name": "uncharacterized protein LOC554678 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013505" }, "gene_names": [ { "name": "si:rp71-1i20.2", "type": "recommended", "evidence": [ { "id": "A8DZ56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DZ56" } ] }, { "name": "im:7148368", "type": "synonym", "evidence": [ { "id": "NP_001013505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013505" }, { "id": "A8DZ56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DZ56" } ] }, { "name": "si:rp71-1i20.2", "type": "synonym", "evidence": [ { "id": "NP_001013505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013505" } ] }, { "name": "wu:fa95b07", "type": "synonym", "evidence": [ { "id": "NP_001013505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013505" }, { "id": "A8DZ56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DZ56" } ] }, { "name": "zgc:113457", "type": "synonym", "evidence": [ { "id": "NP_001013505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013505" }, { "id": "A8DZ56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DZ56" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC554678 precursor", "type": "synonym", "evidence": [ { "id": "A8DZ56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DZ56/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC554678 precursor", "type": "synonym", "evidence": [ { "id": "NP_001013505", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013505" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01026077.1, GDQQ01052961.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On or before Aug 29, 2018 this sequence version replaced XP_009294254.1, NP_001013505.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001013505", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013505" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8DZ56", "url": "https://www.uniprot.org/uniprotkb/A8DZ56" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:rp71-1i20.2", "url": "https://www.uniprot.org/uniprotkb/A8DZ56", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040724-207", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040724-207", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "554678", "url": "https://www.ncbi.nlm.nih.gov/gene/554678", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:554678", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:554678", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A8DZ56", "url": "https://www.orthodb.org/?gene=A8DZ56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001013505", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013505", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A8DZ56", "url": "https://www.uniprot.org/uniprotkb/A8DZ56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8DZ56-1", "url": "https://www.uniprot.org/uniprotkb/A8DZ56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040724-207", "url": "https://zfin.org/ZDB-GENE-040724-207", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKFVFSVLAVLLCFLNNDMTGVYADAVLVSVTVGDSVTLHTAGVKNLQPADVKWYFNDIRIAQLDGDLRFNCTDIQCNDRTEIFIDRLRLDRKTGALTIVNITNTHSGVYQLVVIGGGGTIFNVTVHDDPATHYNKVKKNQGESVTFNPGVRRDQIVELKCLLNNTLIAEISVNQSQICADVQCKERFTDRLKLDNESASLTITKTSIKDSGNYKLVILISSDRRFSITREKRFSLTVTSLSPSQLSGGAIAGIVVMLLLLL", "length": 262, "header": "tr|A8DZ56-1|A8DZ56_DANRE Isoform 1 of Uncharacterized protein LOC554678 precursor OS=Danio rerio OX=7955 GN=si:rp71-1i20.2 PE=4 SV=1 CANONICAL=A8DZ56-1" }, "isoforms": [ { "isoform_ac": "A8DZ56-1", "url": "https://www.uniprot.org/uniprotkb/A8DZ56/entry#A8DZ56-1", "sequence": { "sequence": "MKFVFSVLAVLLCFLNNDMTGVYADAVLVSVTVGDSVTLHTAGVKNLQPADVKWYFNDIRIAQLDGDLRFNCTDIQCNDRTEIFIDRLRLDRKTGALTIVNITNTHSGVYQLVVIGGGGTIFNVTVHDDPATHYNKVKKNQGESVTFNPGVRRDQIVELKCLLNNTLIAEISVNQSQICADVQCKERFTDRLKLDNESASLTITKTSIKDSGNYKLVILISSDRRFSITREKRFSLTVTSLSPSQLSGGAIAGIVVMLLLLL", "length": 262, "header": "tr|A8DZ56-1|A8DZ56_DANRE Isoform 1 of Uncharacterized protein LOC554678 precursor OS=Danio rerio OX=7955 GN=si:rp71-1i20.2 PE=4 SV=1 CANONICAL=A8DZ56-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2002", "authors": "Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA", "evidence": [ { "database": "UniProtKB", "id": "A8DZ56", "url": "https://www.uniprot.org/uniprotkb/A8DZ56" } ], "reference": [ { "type": "PubMed", "id": "12477932", "url": "https://glygen.org/publication/PubMed/12477932" } ] }, { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "A8DZ56", "url": "https://www.uniprot.org/uniprotkb/A8DZ56" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] } ], "pathway": [ { "id": "dre:554678", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:554678", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" }, { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 164, "end_pos": 166, "annotation": "n_glycosylation_sequon" }, { "start_pos": 174, "end_pos": 176, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A8DZ56", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8DZ56" }, { "id": "SM00409", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00409" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Immunoglobulin", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 127, "start_aa": "Ala", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 }, { "start_pos": 123, "end_pos": 125 }, { "start_pos": 164, "end_pos": 166 }, { "start_pos": 174, "end_pos": 176 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A8E4S7-1", "uniprot_ac": "A8E4S7", "uniprot_id": "MB213_DANRE", "mass": { "chemical_mass": 45062.0, "monoisotopic_mass": 45062.0 }, "refseq": { "ac": "NP_001103495", "name": "protein mab-21-like 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103495" }, "gene_names": [ { "name": "mab21L3", "type": "recommended", "evidence": [ { "id": "A8E4S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E4S7" } ] }, { "name": "mab21l3", "type": "synonym", "evidence": [ { "id": "NP_001103495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103495" } ] }, { "name": "si:ch211-246m4.3", "type": "synonym", "evidence": [ { "id": "NP_001103495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103495" }, { "id": "A8E4S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E4S7" } ] } ], "protein_names": [ { "name": "Protein mab-21-like 3", "type": "recommended", "evidence": [ { "id": "A8E4S7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E4S7/entry#names_and_taxonomy" } ] }, { "name": "protein mab-21-like 3", "type": "synonym", "evidence": [ { "id": "NP_001103495", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103495" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC153314.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476776, SAMEA4476798 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC153314.1. On Oct 21, 2007 this sequence version replaced XP_686443.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001103495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103495" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8E4S7", "url": "https://www.uniprot.org/uniprotkb/A8E4S7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mab21L3", "url": "https://www.uniprot.org/uniprotkb/A8E4S7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-242", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-242", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A8E4S7", "url": "https://alphafold.ebi.ac.uk/entry/A8E4S7", "database": "AlphaFoldDB", "categories": [] }, { "id": "558164", "url": "https://www.ncbi.nlm.nih.gov/gene/558164", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558164", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558164", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WSKKARW", "url": "https://omabrowser.org/oma/group/WSKKARW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A8E4S7", "url": "https://www.orthodb.org/?gene=A8E4S7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A8E4S7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A8E4S7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001103495", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001103495", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A8E4S7", "url": "https://www.uniprot.org/uniprotkb/A8E4S7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8E4S7-1", "url": "https://www.uniprot.org/uniprotkb/A8E4S7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-242", "url": "https://zfin.org/ZDB-GENE-070912-242", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTNCTDEDLDNYLLNQVDLRHRQVSKCVEDVQKIIKDLTTEVSSKDARFQSIANAGVHNASLKDQPALMSKWSALLRGRCAYNPAIQVLSPTLYLISVPLQGLMGYKERRTRQWRYYTLTGSRLLSPVREPEKLHQWLELESFVNPSQEWHDARMTIEGDIVPAKVVNVFKDLLETSIKTRGLTNKVSVLESVGTAVRVAVETSEAQIEVKLVPTVELMNYWPKRARWPRLFRRWPSTERARCIKSFGFNLMASSNYHWLLSFSRAEQVLLSNIDEDGGCRRKCYRVVRQLKEDGWCPGSKPVITAFHLQTLLFWTCEKYPCTRDWKDFRGCVLRLVQKLHKCVSQHYLRHYFIRSHNLLKYSNTNELDEVAKKINHFLENPGTYIH", "length": 387, "header": "sp|A8E4S7-1|MB213_DANRE Isoform 1 of Protein mab-21-like 3 OS=Danio rerio OX=7955 GN=mab21L3 PE=2 SV=1 CANONICAL=A8E4S7-1" }, "isoforms": [ { "isoform_ac": "A8E4S7-1", "url": "https://www.uniprot.org/uniprotkb/A8E4S7/entry#A8E4S7-1", "sequence": { "sequence": "MTNCTDEDLDNYLLNQVDLRHRQVSKCVEDVQKIIKDLTTEVSSKDARFQSIANAGVHNASLKDQPALMSKWSALLRGRCAYNPAIQVLSPTLYLISVPLQGLMGYKERRTRQWRYYTLTGSRLLSPVREPEKLHQWLELESFVNPSQEWHDARMTIEGDIVPAKVVNVFKDLLETSIKTRGLTNKVSVLESVGTAVRVAVETSEAQIEVKLVPTVELMNYWPKRARWPRLFRRWPSTERARCIKSFGFNLMASSNYHWLLSFSRAEQVLLSNIDEDGGCRRKCYRVVRQLKEDGWCPGSKPVITAFHLQTLLFWTCEKYPCTRDWKDFRGCVLRLVQKLHKCVSQHYLRHYFIRSHNLLKYSNTNELDEVAKKINHFLENPGTYIH", "length": 387, "header": "sp|A8E4S7-1|MB213_DANRE Isoform 1 of Protein mab-21-like 3 OS=Danio rerio OX=7955 GN=mab21L3 PE=2 SV=1 CANONICAL=A8E4S7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "A8E4S7", "url": "https://www.uniprot.org/uniprotkb/A8E4S7" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:558164", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558164", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8D0IHT2-1", "protein_name": "Mab-21 like 3", "gene_name": "MAB21L3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MYTFPEKFRPQRRTSLATLLTSAVCTERQAENIAVPLRIDQEAMKSPTEGNLDDCLLNKVDLRRQWISQMVEEVQKVVHHLTTEISHQDIRFQAIPCSDTYNENIKVLAPTHFLVTVPLRGLAGYREARQKRWRYYTLQGGRLPCPLRDPEALQQWLEVEQFLKNLWQWHEADVNIEGDIVPARVLQVFRKLVENAIETCHLPGNEVSMLMDRPGVWVAVETFAGPVELELIPSVEIPTSWSKKARWPPCLRRWPSAERVQCIKSFGFSLLACSNYHWQLSFLRAEQVLLEQLDEDGGCRRKCFQALRQMKEDVWCPGKRPVITSHHLQMVLFWTCEKYPHPKDWRIFSKAFLRLVRKLHKCVSQHFLKHYFVRKSNLLRYANSGELDAMAQKLAFFLKNPEITLS", "length": 406 }, "evidence": [ { "id": "A8E4S7", "url": "https://omabrowser.org/oma/group/A8E4S7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1A7G6-1", "protein_name": "Mab-21 like 3", "gene_name": "MAB21L3", "tax_id": 9031, "organism": "Gallus gallus", 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"MADELSRVGKETCSEQVRRSHVSGPCSQFQRRFIQRVSLLRKLPTRFVLHPERKQKVAALPGNDQEAMKCLPEGDLDHCLLSKMDLRQQQISQTVEEVQKIVHLLTTEISHHDSRFEAVPASDTYNDSIKVLAPSLFHVTVPLRGLAGYKGVRTPRWRYYSLQGTKLSCPLRDPEGLQQWLETETFMKTLWQWHKVDVNIEGDIVPAKVLQIFQMLVENAVRTCHLSGKVTVLEKRTTVWVAVETSTGQVELELAPTVEIPTTWPEKAQWPRCLKRWPSPERVECIKSFGFNLVAQSTYHWQLSFSQAERVLCEQLDEDGGCRRRCFQVLRQLKEDVWCPGRRPVITTHHLQTVLFWTCEKYPHLKDWQVFHQAFLRLVRKLHRCVSQHFLKHYFVPKSNLFQSANPSELDAVAQKVAFFLKNPQLELP", "length": 429 }, "evidence": [ { "id": "RGD:1308694", "url": "https://alliancegenome.org/gene/RGD:1308694#orthology", "database": "AGR" }, { "id": "HGNC:26787", "url": "https://alliancegenome.org/gene/HGNC:26787#orthology", "database": "AGR" }, { "id": "MGI:2446273", "url": "https://alliancegenome.org/gene/MGI:2446273#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-242", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-242#orthology", "database": "AGR" }, { "id": "A8E4S7", "url": "https://omabrowser.org/oma/group/A8E4S7/", "database": 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"url": "https://alliancegenome.org/gene/HGNC:26787#orthology", "database": "AGR" }, { "id": "MGI:2446273", "url": "https://alliancegenome.org/gene/MGI:2446273#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-242", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-242#orthology", "database": "AGR" }, { "id": "A8E4S7", "url": "https://omabrowser.org/oma/group/A8E4S7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 3, "end_pos": 5, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 3, "end_pos": 5 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A8E7D3-1", "uniprot_ac": "A8E7D3", "uniprot_id": "COX14_DANRE", "mass": { "chemical_mass": 6790.0, "monoisotopic_mass": 6790.0 }, "refseq": { "ac": "NP_001289695", "name": "cytochrome c oxidase assembly protein COX14 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289695" }, "gene_names": [ { "name": "cox14", "type": "synonym", "evidence": [ { "id": "NP_001289695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289695" } ] }, { "name": "si:dkey-222f2.8", "type": "synonym", "evidence": [ { "id": "NP_001289695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289695" }, { "id": "A8E7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E7D3" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase assembly protein COX14 homolog", "type": "recommended", "evidence": [ { "id": "A8E7D3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8E7D3/entry#names_and_taxonomy" } ] }, { "name": "COX14 cytochrome c oxidase assembly factor", "type": "synonym", "evidence": [ { "id": "NP_001289695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289695" } ] }, { "name": "cytochrome c oxidase assembly homolog 14", "type": "synonym", "evidence": [ { "id": "NP_001289695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289695" } ] }, { "name": "cytochrome c oxidase assembly protein COX14 homolog", "type": "synonym", "evidence": [ { "id": "NP_001289695", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289695" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH557256.1, EH539630.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH557256.1. On Nov 12, 2014 this sequence version replaced XP_005161690.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001289695", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001289695" } ] }, { "annotation": "Plays a role in the assembly or stability of the cytochrome c oxidase complex (COX).", "evidence": [ { "database": "UniProtKB", "id": "A8E7D3", "url": "https://www.uniprot.org/uniprotkb/A8E7D3#function" } ] } ], "disease": [ { "disease_id": "DOID:0070496", "recommended_name": { "id": "DOID:0070496", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070496", "name": "mitochondrial complex IV deficiency nuclear type 10", "description": "A COX deficiency, benign infantile mitochondrial myopathy that has_material_basis_in homozygous mutation in the COX14 gene on chromosome 12q13.12." }, "synonyms": [ { "id": "DOID:0070496", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070496", "name": "MC4DN10", "description": "" }, { "id": "MONDO:0033639", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033639", "name": "mitochondrial complex IV deficiency, nuclear type 10", "description": "Any mitochondrial complex IV deficiency in which the cause of the disease is a mutation in the COX14 gene." }, { "id": "MONDO:0033639", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033639", "name": "MC4DN10", "description": "" }, { "id": "MONDO:0033639", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033639", "name": "mitochondrial complex IV deficiency, nuclear type 10", "description": "" }, { "id": "MIM:619053", "resource": "MIM", "url": "https://www.omim.org/entry/619053", "name": "Mitochondrial complex IV deficiency, nuclear type 10", "description": "Mitochondrial complex IV deficiency, nuclear type 10" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070496", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070496" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8E7D3", "url": "https://www.uniprot.org/uniprotkb/A8E7D3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/A8E7D3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-626", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-626", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A8E7D3", "url": "https://alphafold.ebi.ac.uk/entry/A8E7D3", "database": "AlphaFoldDB", "categories": [] }, { "id": "568423", "url": "https://www.ncbi.nlm.nih.gov/gene/568423", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029208", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029208", "database": "InterPro", "categories": [ 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Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "A8E7D3", "url": "https://www.uniprot.org/uniprotkb/A8E7D3" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] } ], "pathway": [ { "id": "dre:568423", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568423", "resource": "KEGG Pathway" }, { "id": "R-DRE-9864848", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9864848", "resource": "Reactome", "description": "Complex 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] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8E7S3", "url": "https://www.uniprot.org/uniprotkb/A8E7S3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sdr16c5a", "url": "https://www.uniprot.org/uniprotkb/A8E7S3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040426-2049", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2049", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000016233", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000016233", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd05339", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd05339", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "405814", "url": "https://www.ncbi.nlm.nih.gov/gene/405814", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:405814", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:405814", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A8E7S3", "url": "https://www.orthodb.org/?gene=A8E7S3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24322", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24322", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24322:SF747", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24322:SF747", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_998043", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_998043", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A8E7S3", "url": "https://www.uniprot.org/uniprotkb/A8E7S3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8E7S3-1", "url": "https://www.uniprot.org/uniprotkb/A8E7S3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040426-2049", "url": "https://zfin.org/ZDB-GENE-040426-2049", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNILLETLRLIFLTVYYNLEAFLKFFIPLRKKDVSGEIVLITGSGSGIGRLMALEFASLDVSLVLWDINVDGLKETAEQVKEKGASRVHYYQCDCSDREAVYRVADQVKSEIGDVTILINNAGIVSGKKFMDTPDALIEKTLRVNAMSHFWTYKAFLPAMMDKNHGHLVSVASSAGLIGVNGLADYCASKFAAVGFAESVALELLSAGKDGIKTTIVCPFLINTGLFDGCGTKWPLLMPMLEPDYVAKRIVSAILTDQVFVLLPRSLYFLMALKGVIPYKQSVILGMYFGAFNFMDAFKGREKKRD", "length": 306, "header": "tr|A8E7S3-1|A8E7S3_DANRE Isoform 1 of Short chain dehydrogenase/reductase family 16C, member 5a OS=Danio rerio OX=7955 GN=sdr16c5a PE=1 SV=1 CANONICAL=A8E7S3-1" }, "isoforms": [ { "isoform_ac": "A8E7S3-1", "url": "https://www.uniprot.org/uniprotkb/A8E7S3/entry#A8E7S3-1", "sequence": { "sequence": "MNILLETLRLIFLTVYYNLEAFLKFFIPLRKKDVSGEIVLITGSGSGIGRLMALEFASLDVSLVLWDINVDGLKETAEQVKEKGASRVHYYQCDCSDREAVYRVADQVKSEIGDVTILINNAGIVSGKKFMDTPDALIEKTLRVNAMSHFWTYKAFLPAMMDKNHGHLVSVASSAGLIGVNGLADYCASKFAAVGFAESVALELLSAGKDGIKTTIVCPFLINTGLFDGCGTKWPLLMPMLEPDYVAKRIVSAILTDQVFVLLPRSLYFLMALKGVIPYKQSVILGMYFGAFNFMDAFKGREKKRD", "length": 306, "header": "tr|A8E7S3-1|A8E7S3_DANRE Isoform 1 of Short chain dehydrogenase/reductase family 16C, member 5a OS=Danio rerio OX=7955 GN=sdr16c5a PE=1 SV=1 CANONICAL=A8E7S3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A8E7S3", "url": "https://www.uniprot.org/uniprotkb/A8E7S3" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "A8E7S3", "url": "https://www.uniprot.org/uniprotkb/A8E7S3" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] } ], "pathway": [ { "id": "dre:405814", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:405814", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZS85-1", "protein_name": "Short chain dehydrogenase/reductase family 16C, member 5", "gene_name": "Sdr16c5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPCNLESAKDLLVFLGKSLLSILEALLSHVISKPRKNVAGEVVLITGAGSGLGRLLALQFARLGSVLVLWDVNKETNEETRQIAQEAGAIRVHAYTCDCSQREEVYRVADQVKKEVGDVSILINNAGIVTGRKFLDCPDDLMEKSLDVNFKAHLWMYKAFLPAMIANNHGHLVCISSSAGLIGVNGLSDYCASKFAALGFAESMFVETLAQKQRGIKTTIVCPFFIKTGMFEGCTTKCPNLLPILDPEYAVRKIVDAILQEQLYLYMPKFLYFIMFLKSFLPIKTGILIADYLGLFHVMDGFTGQKKKS", "length": 309 }, "evidence": [ { "id": "MGI:2668443", "url": "https://alliancegenome.org/gene/MGI:2668443#orthology", "database": "AGR" }, { "id": "HGNC:30311", "url": "https://alliancegenome.org/gene/HGNC:30311#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q06417-1", "protein_name": "Uncharacterized oxidoreductase TDA5", "gene_name": "TDA5", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNIDCLCRWVVLPLLRYPLLVALVLRWSLSDSISICLTIYTLLINAFLIANSYIKRSGQVAWKSLREFKNGIVLITGGSKGLGRAIVSQLLQDYSNLTILNVDICPSSVRNTRVKDLICDLSDDEEVAALLNLLKRKYKNEIRLIVNNAGVRANFTGFNGMERDNLDKIFKINTFAPLQFIQELAPSRHSTRQCYIVNIASILGILTPAKVAAYAASKAALIAFHQSYSFELQNEGVRNIRTLLVTPGQLNTEMFAGFKPPRQFFAPVIDITTLAAKIVRYCELGQRGQLNEPFYCSFAHLLMCVPYSLQRIVRSFSRIDCCLPDE", "length": 326 }, "evidence": [ { "id": "MGI:2668443", "url": "https://alliancegenome.org/gene/MGI:2668443#orthology", "database": "AGR" }, { "id": "HGNC:30311", "url": "https://alliancegenome.org/gene/HGNC:30311#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q07530-1", "protein_name": "Uncharacterized oxidoreductase YDL114W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVRKNKINRASGTTKHLKDFPSVILSLPSYNPSILSKNATALITGGSSGLGFELAKELSRRINKVIVADIQSFPTFAQVEYNNIFYYQCDITSLDEIKNLKKAIERDHGNINIIINNAGVAHIKKLEHMTNKEVEQLIDINLIGAYRIISTFAEDMIDNREGFIINIASVLGELTPARLTSYGASKGAMIGFHKCMSRHFRSLSTECNKTGIKTLLVCPGKIKTNMFIDVPTPSKLLAPDIIPSQLALAIISAMEHNHLQTLNAPYYVNLVPFFKTLSWPYRHLLKHFSGMDHVTSTSPRAINPKRSA", "length": 308 }, "evidence": [ { "id": "MGI:2668443", "url": "https://alliancegenome.org/gene/MGI:2668443#orthology", "database": "AGR" }, { "id": "HGNC:30311", "url": "https://alliancegenome.org/gene/HGNC:30311#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q7TQA3-1", "protein_name": "Epidermal retinol dehydrogenase 2", "gene_name": "Sdr16c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQNLESVKNLLVFLGKSLLSVLEALLFHVISKPRKNVAGEIVLITGAGSGLGRLLALQFARLGAVLVLWDVNKEANDETHQLAREAGAARVHAYTCDCSRREEVYRVADQVKKEVGDVSILINNAGIVTGRNFLDCPDDLMEKSFDVNFKAHLWMYKAFLPAMIANNHGHLVCISSSAGLIGVNGLSDYCASKFAALGFAESMFIETLAKKQWGIKTTIVCPFFIKTGMFEGCTTKCPTLLPILDPEYAVRKIIDAILQEQLYLYMPKFLYFIVFLKSILPIKTGILIADYLGVFHMTEGFTGQKKKT", "length": 309 }, "evidence": [ { "id": "MGI:2668443", "url": "https://alliancegenome.org/gene/MGI:2668443#orthology", "database": "AGR" }, { "id": "HGNC:30311", "url": "https://alliancegenome.org/gene/HGNC:30311#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2049", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2049#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N3Y7-1", "protein_name": "Epidermal retinol dehydrogenase 2", "gene_name": "SDR16C5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFNLQSSKKLFIFLGKSLFSLLEAMIFALLPKPRKNVAGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWTYKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGIKTTIVCPFFIKTGMFEGCTTGCPSLLPILEPKYAVEKIVEAILQEKMYLYMPKLLYFMMFLKSFLPLKTGLLIADYLGILHAMDGFVDQKKKL", "length": 309 }, "evidence": [ { "id": "MGI:2668443", "url": "https://alliancegenome.org/gene/MGI:2668443#orthology", "database": "AGR" }, { "id": "HGNC:30311", "url": "https://alliancegenome.org/gene/HGNC:30311#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-2049", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-2049#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VIG6-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG9265", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKNNNELSAEDAQILANGHAHPNANGVVHQKTEPVAPAADGWRQVLWNTWDAFADVAWFIICCIGYILQDLYYIAFGYPEKELNTDIALITGGGNGLGRLLAERLGKMGTKVVIWDINKKGIAETVQIVEEAGGYCKGYVVDISKKEEVYKAADVIRDEVGDITLLINNAGVVSGLHLLDTPDHLIERSFNVNVMAHFWTTKAFLPKMIENDRGHIATIASLAGHVGISKLVDYCASKFAAVGFDEALRLELEVLGHTNIRTTCICPFFIQATGMFDDVNARWVPTLNPNDVADRVIAAIRKNEKLAVIPGFLKVLLSFKWTFPWGCVGGLLKRLVPDASPHGLPSSIAVPTVPLNSNSKLTAADIAALDAELSSVTLPAKPPSMLIQRTPSLGERVL", "length": 399 }, "evidence": [ { "id": "MGI:2668443", "url": "https://alliancegenome.org/gene/MGI:2668443#orthology", "database": "AGR" }, { "id": "HGNC:30311", "url": "https://alliancegenome.org/gene/HGNC:30311#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VR28-1", "protein_name": "Short-chain dehydrogenase/reductase family 16C member 6", "gene_name": "Dmel\\CG15629", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTASPGLLHMDQPLRAIYQFLLDLLVFTIKSVYYVLESIYYSLLPQRFRKLKDISGQVVLITGGGGGVGRLIALNFARLQARIVIWDINQEAIKTTVDLLAKHGYDNCKGYVVDISDREQIYQRASQVTEEVGPVDILINNAGIVCCKPFWELHDRVIQNTYNINIISHYWTVKAFLPHMMRNNRGHIVTVGSVTGMLGTYGCSDYAATKYACIGFHESLLTDLKAHGYDQIQMSLICPYYINTGMFSGVRPRMMPMLEPQYVADRIENAVRCNEVWCVLPNSIRLLTPLKCLLPAKMCWELMSRVIRGPESMMMFQGRGRVAAG", "length": 325 }, "evidence": [ { "id": "MGI:2668443", "url": "https://alliancegenome.org/gene/MGI:2668443#orthology", "database": "AGR" }, { "id": "HGNC:30311", "url": "https://alliancegenome.org/gene/HGNC:30311#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "lipid droplet", "id": "GO:0005811", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005811", "evidence": [ { "database": "UniProtKB", "id": "A8E7S3", "url": "https://www.uniprot.org/uniprotkb/A8E7S3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "all-trans-retinol dehydrogenase (NAD+) activity", "id": "GO:0004745", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004745", "evidence": [ { "database": "UniProtKB", "id": "A8E7S3", "url": "https://www.uniprot.org/uniprotkb/A8E7S3" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "A8E7S3", "url": "https://www.uniprot.org/uniprotkb/A8E7S3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.1.1.105", "ec_name": "all-trans-retinol + NAD(+) = all-trans-retinal + NADH + H(+).", "evidence": [ { "id": "1.1.1.105", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.105" }, { "id": "1.1.1.105", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.1.105" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A8WHM9-1", "uniprot_ac": "A8WHM9", "uniprot_id": "A8WHM9_DANRE", "mass": { "chemical_mass": 52675.0, "monoisotopic_mass": 52675.0 }, "refseq": { "ac": "NP_001107120", "name": "uncharacterized protein LOC100003064", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107120" }, "gene_names": [ { "name": "si:ch211-163b2.4", "type": "recommended", "evidence": [ { "id": "A8WHM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WHM9" } ] }, { "name": "si:ch211-163b2.4", "type": "synonym", "evidence": [ { "id": "NP_001107120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107120" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100003064", "type": "synonym", "evidence": [ { "id": "A8WHM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WHM9/entry#names_and_taxonomy" } ] }, { "name": "Uncharacterized protein isoform X1", "type": "synonym", "evidence": [ { "id": "A8WHM9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WHM9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100003064", "type": "synonym", "evidence": [ { "id": "NP_001107120", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107120" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## CDS exon combination :: SRR32588717.12345362.1 [ECO:0000331] RNAseq introns :: single sample supports all introns SAMEA898404, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000008.1. On Jan 20, 2008 this sequence version replaced XP_001342707.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001107120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107120" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8WHM9", "url": "https://www.uniprot.org/uniprotkb/A8WHM9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-163b2.4", "url": "https://www.uniprot.org/uniprotkb/A8WHM9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-502", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-502", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000094890", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000094890", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100003064", "url": "https://www.ncbi.nlm.nih.gov/gene/100003064", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100003064", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003064", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EQITIMF", "url": "https://omabrowser.org/oma/group/EQITIMF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A8WHM9", "url": "https://www.orthodb.org/?gene=A8WHM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31025", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31025", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31025:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31025:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001107120", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107120", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A8WHM9", "url": "https://www.uniprot.org/uniprotkb/A8WHM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A8WHM9-1", "url": "https://www.uniprot.org/uniprotkb/A8WHM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-502", "url": "https://zfin.org/ZDB-GENE-081104-502", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSTSGLLLVINALNDSGPSTPQSSASFDTDTLSLTSKSSEDSDWFSPKRFRKDEDEASQNSQARDLIKQILETRPGGANVLREYEDTGTINDETRKVMVNILVAHMMETEGRVPHRLTKQKYGLGIITLFPSLRDPQGRTGYEHFYDGQKNSGFLSWRLKTVQRGTKPSGNKDDPKTEEKGGPLLDRQLCHPEDQLDSDQSLEAISLMNHTSDREVIMQKMRATFKYRQRLVRDPEKSTTILSVFPRFLDTKGLILQDFTLLFGSETASRLLERWPTVFKSKIIKLAETLTSTPLLKRLLSSAKQNKESSEAEDFPEWDSDISSFLLLLHFLSPQVSGRKKIQKMSISQAIDHLVVFQKACRSIQEHLETEDNRQPYILAIGSSKEAISQFFIVLDKKLIPCQESSSLAAIDELFKVHFVFSISYDPPLKGLFTFLQTTVYRIDVGSTSETPRVKELRAKLLNDV", "length": 465, "header": "tr|A8WHM9-1|A8WHM9_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-163b2.4 PE=4 SV=1 CANONICAL=A8WHM9-1" }, "isoforms": [ { "isoform_ac": "A8WHM9-1", "url": "https://www.uniprot.org/uniprotkb/A8WHM9/entry#A8WHM9-1", "sequence": { "sequence": "MSTSGLLLVINALNDSGPSTPQSSASFDTDTLSLTSKSSEDSDWFSPKRFRKDEDEASQNSQARDLIKQILETRPGGANVLREYEDTGTINDETRKVMVNILVAHMMETEGRVPHRLTKQKYGLGIITLFPSLRDPQGRTGYEHFYDGQKNSGFLSWRLKTVQRGTKPSGNKDDPKTEEKGGPLLDRQLCHPEDQLDSDQSLEAISLMNHTSDREVIMQKMRATFKYRQRLVRDPEKSTTILSVFPRFLDTKGLILQDFTLLFGSETASRLLERWPTVFKSKIIKLAETLTSTPLLKRLLSSAKQNKESSEAEDFPEWDSDISSFLLLLHFLSPQVSGRKKIQKMSISQAIDHLVVFQKACRSIQEHLETEDNRQPYILAIGSSKEAISQFFIVLDKKLIPCQESSSLAAIDELFKVHFVFSISYDPPLKGLFTFLQTTVYRIDVGSTSETPRVKELRAKLLNDV", "length": 465, "header": "tr|A8WHM9-1|A8WHM9_DANRE Isoform 1 of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-163b2.4 PE=4 SV=1 CANONICAL=A8WHM9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A8WHM9", "url": "https://www.uniprot.org/uniprotkb/A8WHM9" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100003064", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003064", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "A8WHM9", "url": "https://www.uniprot.org/uniprotkb/A8WHM9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "microtubule binding", "id": "GO:0008017", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008017", "evidence": [ { "database": "UniProtKB", "id": "A8WHM9", "url": "https://www.uniprot.org/uniprotkb/A8WHM9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 209, "end_pos": 211, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 209, "end_pos": 211 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", 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"MASRIDQLAKPKTNLLKFPDRRSVYWLDELPSRPKSSTTAFETTPRLEKLVQSKRPIHFYEDNRRSVEWVVSAAALKACPSQRVCSLALPRPPADGWQPDRPLMDTLSVAVKTAKPSPRICYLAQPKQIKMTLTHFSVESSEHEIGISTTPSARLLRLASPKQVHPQHTLARSVSWPIPKHVLKAGASERLQVLARPKTRQALFEGYNPYRVSPAAGSATASPRLLELSLPLPRKCREQ", "length": 239, "header": "tr|A8WHR5-1|A8WHR5_DANRE Isoform 1 of Sperm microtubule associated protein 2 OS=Danio rerio OX=7955 GN=spmap2 PE=4 SV=1 CANONICAL=A8WHR5-1" }, "isoforms": [ { "isoform_ac": "A0AC58GY49-1", "url": "https://www.uniprot.org/uniprotkb/A8WHR5/entry#A0AC58GY49-1", "sequence": { "sequence": "MDTLSVAVKTAKPSPRICYLAQPKQIKMTLTHFSVESSEHEIGISTTPSARLLRLASPKQVHPQHTLARSVSWPIPKHVLKAGASERLQVLARPKTRQALFEGYNPYRVSPAAGSATASPRLLELSLPLPRKCREQ", "length": 136, "header": "tr|A0AC58GY49-1|A0AC58GY49_DANRE Computationally mapped isoform of Sperm microtubule associated protein 2 isoform X2 OS=Danio rerio OX=7955 GN=spmap2 PE=4 SV=1 CANONICAL=A8WHR5-1" }, "locus": {} }, { "isoform_ac": "A0AC58GY60-1", "url": "https://www.uniprot.org/uniprotkb/A8WHR5/entry#A0AC58GY60-1", "sequence": { "sequence": "MASRIDQLAKPKTNLLKFPDRRSVYWLDELPSRPKSSTTAFETTPRLEKLVQSKRPIHFYEDNRSVEWVVSAAALKACPSQRVCSLALPRPPADGWQPDRPLMDTLSVAVKTAKPSPRICYLAQPKQIKMTLTHFSVESSEHEIGISTTPSARLLRLASPKQVHPQHTLARSVSWPIPKHVLKAGASERLQVLARPKTRQALFEGYNPYRVSPAAGSATASPRLLELSLPLPRKCREQ", "length": 238, "header": "tr|A0AC58GY60-1|A0AC58GY60_DANRE Computationally mapped isoform of Sperm microtubule associated protein 2 isoform X1 OS=Danio rerio OX=7955 GN=spmap2 PE=4 SV=1 CANONICAL=A8WHR5-1" }, "locus": {} }, { "isoform_ac": "A0AC58GY86-1", "url": "https://www.uniprot.org/uniprotkb/A8WHR5/entry#A0AC58GY86-1", "sequence": { "sequence": "MASRIDQLAKPKTNLLKFPDRRSVYWLDELPSRPKSSTTAFETTPRLEKLVQSKRPIHFYEDNRSVEWVVSAAALKACPSQRVCSLALPRPPADGWQPDRPLMDTRLHPLKASHSKSTQAEPSVLK", "length": 126, "header": "tr|A0AC58GY86-1|A0AC58GY86_DANRE Computationally mapped isoform of Sperm microtubule associated protein 2 isoform X4 OS=Danio rerio OX=7955 GN=spmap2 PE=4 SV=1 CANONICAL=A8WHR5-1" }, "locus": {} }, { "isoform_ac": "A0AC58GY87-1", "url": "https://www.uniprot.org/uniprotkb/A8WHR5/entry#A0AC58GY87-1", "sequence": { "sequence": "MASRIDQLAKPKTNLLKFPDRRSVYWLDELPSRPKSSTTAFETTPRLEKLVQSKRPIHFYEDNRRSVEWVVSAAALKACPSQRVCSLALPRPPADGWQPDRPLMDTRLHPLKASHSKSTQAEPSVLK", "length": 127, "header": "tr|A0AC58GY87-1|A0AC58GY87_DANRE Computationally mapped isoform of Sperm microtubule associated protein 2 isoform X3 OS=Danio rerio OX=7955 GN=spmap2 PE=4 SV=1 CANONICAL=A8WHR5-1" }, "locus": {} }, { "isoform_ac": "A8WHR5-1", "url": "https://www.uniprot.org/uniprotkb/A8WHR5/entry#A8WHR5-1", "sequence": { "sequence": "MASRIDQLAKPKTNLLKFPDRRSVYWLDELPSRPKSSTTAFETTPRLEKLVQSKRPIHFYEDNRRSVEWVVSAAALKACPSQRVCSLALPRPPADGWQPDRPLMDTLSVAVKTAKPSPRICYLAQPKQIKMTLTHFSVESSEHEIGISTTPSARLLRLASPKQVHPQHTLARSVSWPIPKHVLKAGASERLQVLARPKTRQALFEGYNPYRVSPAAGSATASPRLLELSLPLPRKCREQ", "length": 239, "header": "tr|A8WHR5-1|A8WHR5_DANRE Isoform 1 of Sperm microtubule associated protein 2 OS=Danio rerio OX=7955 GN=spmap2 PE=4 SV=1 CANONICAL=A8WHR5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A8WHR5", "url": "https://www.uniprot.org/uniprotkb/A8WHR5" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A8WHR5", "url": "https://www.uniprot.org/uniprotkb/A8WHR5" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:561308", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561308", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5XHX8-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGELGEHRSRSSLLSIPVLDTKTSGGSEYRESDGSLDLQSTLFEDHWLQSSQATTERNTDDPEEEIPPEEMVGEELPEVSNLEDSLRRDLEVEVVGMSHLSINERTTPTTSSAKCRKKKNHRLLELAKPKFNWQCLKDRTGRCCKGHVWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPEVSRRVEELSRPKRFYQEYYNNNRTTPIWPIPRSTLEYQASNRLKRLATPKIRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRAPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLNVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELAVPKHITKKV", "length": 378 }, "evidence": [ { "id": "HGNC:13706", "url": "https://alliancegenome.org/gene/HGNC:13706#orthology", "database": "AGR" }, { "id": "MGI:1338756", "url": "https://alliancegenome.org/gene/MGI:1338756#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JMB1-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "Spmap2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGELGEHRASLLSNPIPEVKTLGELKQGQNNGNLDLESEPFGSHWLQGSKATTGRTSEEPEEEIPPEEMAGEELPETSNLDGPLQQDLEVEVVEMSHLSITERTPSVSTAKGRKKRSRRLLELAKPKTNWQCLRDRTGRCCKGYAWISPRKTNLQFCLYWPSVYWTERFIEDTTLTITVPVVSQRMEELSRPKRFYQEYYNNNRTTPIWSIPRSTLEYQASNRLKQLATPKVRNNIWSINMSEVSQVSRAAQMAVPTPRTLRLAKPRPPATLLEEWDPMPKPKPYVSDYNRLLQLATPKALSEKCVPDRSPQWEVLDVTKNAVASSRIISLAQPKIRKDLNEGYNPYYISPASLVAQASPRIYELATPKYITKKV", "length": 375 }, "evidence": [ { "id": "HGNC:13706", "url": "https://alliancegenome.org/gene/HGNC:13706#orthology", "database": "AGR" }, { "id": "MGI:1338756", "url": "https://alliancegenome.org/gene/MGI:1338756#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-59", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-59#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2T0-1", "protein_name": "Sperm microtubule associated protein 2", "gene_name": "SPMAP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDSRRRSLGNQPSSEAAGRSEREQDGDPRGLQSSVYESRRVTDPERQDLDNAELGPEDPEEELPPEEVAGEEFPETLDPKEALSELERVLDKDLEEDIPEISRLSISQKLPSTTMTKARKRRRRRRLMELAEPKINWQVLKDRKGRCGKGYAWISPCKMSLHFCLCWPSVYWTERFLEDTTLTITVPAVSRRVEELSRPKRFYLEYYNNNRTTPVWPIPRSSLEYRASSRLKELAAPKIRDNFWSMPMSEVSQVSRAAQMAVPSSRILQLSKPKAPATLLEEWDPVPKPKPHVSDHNRLLHLARPKAQSDKCVPDRDPRWEVLDVTKKVVASPRIISLAKPKVRKGLNEGYDRRPLASMSLPPPKASPEKCDQPRPGL", "length": 379 }, "evidence": [ { "id": "HGNC:13706", "url": "https://alliancegenome.org/gene/HGNC:13706#orthology", "database": "AGR" }, { "id": "MGI:1338756", "url": "https://alliancegenome.org/gene/MGI:1338756#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-59", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-59#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VD59-1", "protein_name": "Testicular haploid expressed protein", "gene_name": "Theg", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MTIQGLKCDLSPTVTTCLQLKDCVRPDCCPIRDPIPYDAECFVRDIGQELDKLTRRHERMFVKRRRLMEMAIPRRRTCRFVPKCACSFPKSIEMVRPCDAQNHTRTEQLALPTVRRLLHRRRTAILAGDSIGESILNRWLRYSYLSLYSRLTNIQPLVKPKKKKKKTEKQLAKHEKYIEKLAKPKKAPKVPKPDRGAGEFDPVRLNQLASPKAYLEEIKPKWELTSQMKDYKATKRIKQISQPVVRDNVHINENPEKVSPNALRYKPSARIKEMSEPLTTRDANQGLADVKENPFGIAPNALKYKASTRIKELAEPKEFENTHIRENPFAISPAALKAKASPRLIELAKPKGG", "length": 353 }, "evidence": [ { "id": "HGNC:13706", "url": "https://alliancegenome.org/gene/HGNC:13706#orthology", "database": "AGR" }, { "id": "MGI:1338756", "url": "https://alliancegenome.org/gene/MGI:1338756#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermatogenesis", "id": "GO:0007283", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007283", "evidence": [ { "database": "UniProtKB", "id": "A8WHR5", "url": "https://www.uniprot.org/uniprotkb/A8WHR5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A8WIQ4-1", "uniprot_ac": "A8WIQ4", "uniprot_id": "A8WIQ4_DANRE", "mass": { "chemical_mass": 28908.0, "monoisotopic_mass": 28908.0 }, "refseq": { "ac": "NP_001108166", "name": "granzyme 3, tandem duplicate 3 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108166" }, "gene_names": [ { "name": "gzm3.3", "type": "recommended", "evidence": [ { "id": "A8WIQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WIQ4" } ] }, { "name": "gzm3.3", "type": "synonym", "evidence": [ { "id": "NP_001108166", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108166" } ] }, { "name": "si:ch211-165b19.8", "type": "synonym", "evidence": [ { "id": "NP_001108166", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108166" }, { "id": "A8WIQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WIQ4" } ] } ], "protein_names": [ { "name": "Granzyme 3, tandem duplicate 3 precursor", "type": "synonym", "evidence": [ { "id": "A8WIQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A8WIQ4/entry#names_and_taxonomy" } ] }, { "name": "granzyme 3, tandem duplicate 3 precursor", "type": "synonym", "evidence": [ { "id": "NP_001108166", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108166" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01035668.1, GDQQ01061539.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476737, SAMEA4476809 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000009.1. On Feb 21, 2008 this sequence version replaced XP_001341207.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001108166", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108166" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A8WIQ4", "url": "https://www.uniprot.org/uniprotkb/A8WIQ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gzm3.3", "url": "https://www.uniprot.org/uniprotkb/A8WIQ4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-135", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-135", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000093990", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000093990", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": 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The reference sequence was derived from JBMGRA010000002.1. 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Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A8WIT4", "url": "https://www.uniprot.org/uniprotkb/A8WIT4" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A8WIT4", "url": "https://www.uniprot.org/uniprotkb/A8WIT4" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:556220", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556220", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 185, "end_pos": 187, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 185, "end_pos": 187 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A9C3P2-1", "uniprot_ac": "A9C3P2", "uniprot_id": "A9C3P2_DANRE", "mass": { "chemical_mass": 20177.0, "monoisotopic_mass": 20177.0 }, "refseq": { "ac": "NP_001107112", "name": "ankyrin repeat domain-containing protein 39", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107112" }, "gene_names": [ { "name": "ankrd39", "type": "recommended", "evidence": [ { "id": "A9C3P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9C3P2" } ] }, { "name": "ankrd39", "type": "synonym", "evidence": [ { "id": "NP_001107112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107112" } ] }, { "name": "si:ch211-178d20.1", "type": "synonym", "evidence": [ { "id": "NP_001107112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107112" }, { "id": "A9C3P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9C3P2" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 39", "type": "synonym", "evidence": [ { "id": "A9C3P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9C3P2/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 39", "type": "synonym", "evidence": [ { "id": "NP_001107112", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107112" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01014656.1, SRR32588719.7092872.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476768, SAMEA4476782 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000008.1. On Jan 20, 2008 this sequence version replaced XP_001335821.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001107112", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107112" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9C3P2", "url": "https://www.uniprot.org/uniprotkb/A9C3P2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ankrd39", "url": "https://www.uniprot.org/uniprotkb/A9C3P2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-153", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-153", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000041350", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000041350", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100000333", "url": "https://www.ncbi.nlm.nih.gov/gene/100000333", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100000333", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000333", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YCGHLNV", "url": "https://omabrowser.org/oma/group/YCGHLNV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A9C3P2", "url": "https://www.orthodb.org/?gene=A9C3P2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24171:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24171:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001107112", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107112", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A9C3P2", "url": "https://www.uniprot.org/uniprotkb/A9C3P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A9C3P2-1", "url": "https://www.uniprot.org/uniprotkb/A9C3P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-153", "url": "https://zfin.org/ZDB-GENE-081104-153", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNPHGGQCTCSGHLPTPSVHQTLEEMDFERGIWSAAMDGDVERVRMLIKKGTDPNMRDQANYTALHYASRAGHVSVCELLLDCGACVNAQTHGGATPLHRAAYCGHQRVLKLLLERGADPGLTDDDGATPLHKAAEQRCFVVCKLLVKRFPALRDIKDKRSRIPFDLCPEDDSKWEFLKPAQ", "length": 182, "header": "tr|A9C3P2-1|A9C3P2_DANRE Isoform 1 of Ankyrin repeat domain-containing protein 39 OS=Danio rerio OX=7955 GN=ankrd39 PE=4 SV=1 CANONICAL=A9C3P2-1" }, "isoforms": [ { "isoform_ac": "A9C3P2-1", "url": "https://www.uniprot.org/uniprotkb/A9C3P2/entry#A9C3P2-1", "sequence": { "sequence": "MNPHGGQCTCSGHLPTPSVHQTLEEMDFERGIWSAAMDGDVERVRMLIKKGTDPNMRDQANYTALHYASRAGHVSVCELLLDCGACVNAQTHGGATPLHRAAYCGHQRVLKLLLERGADPGLTDDDGATPLHKAAEQRCFVVCKLLVKRFPALRDIKDKRSRIPFDLCPEDDSKWEFLKPAQ", "length": 182, "header": "tr|A9C3P2-1|A9C3P2_DANRE Isoform 1 of Ankyrin repeat domain-containing protein 39 OS=Danio rerio OX=7955 GN=ankrd39 PE=4 SV=1 CANONICAL=A9C3P2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A9C3P2", "url": "https://www.uniprot.org/uniprotkb/A9C3P2" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:100000333", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000333", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZSF1-1", "protein_name": "Ankyrin repeat domain 39", "gene_name": "Ankrd39", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAPQSCADGSCCSHPGAVPGVQQTLEEMDFERGIWSAALNGDLGRVKHFIQKATDPSQPDSAGYTALHYASRNGHYDVCQFLLENGAKCDARTNGGATALHRASYCGHTEIARLLLSHGSNPQLVDDDGMTSLHKVCAVGDCKPPKLNRHRGHCGEQEIKARKDHLESSASPPSPATTLGKRLPHRLLTTETGSPTQ", "length": 198 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-081104-153", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-153#orthology", "database": "AGR" }, { "id": "HGNC:28640", "url": "https://alliancegenome.org/gene/HGNC:28640#orthology", "database": "AGR" }, { "id": "RGD:1559504", "url": "https://alliancegenome.org/gene/RGD:1559504#orthology", "database": "AGR" }, { "id": "MGI:1914816", "url": "https://alliancegenome.org/gene/MGI:1914816#orthology", "database": "AGR" }, { "id": "FB:FBgn0264743", "url": "https://alliancegenome.org/gene/FB:FBgn0264743#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8W4FCQ3-1", "protein_name": "Ankyrin repeat domain 39", "gene_name": "ANKRD39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAAPRSCAEGPCCSHPSAAPSVQQTLDEMDFERGIWSAALNGDLGRVKYLIQKAADPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTRGGATALHRASYCGHTDIARLLLSHGCNPQLVDADGMTSLHKAAEQGHVDICSLLLQHSPALKAIRDRKARLACDLLPHNSDLRDLLAG", "length": 183 }, "evidence": [ { "id": "A9C3P2", "url": "https://omabrowser.org/oma/group/A9C3P2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7K4A1-1", "protein_name": "Ankyrin repeat domain-containing protein 39 isoform X1", "gene_name": "Ankrd39", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAPQPCADGSCCSHPGAVPGAQQTLEEMDFERGEKGIWSAALNGDLGRVKHFIQKATDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTEIARLLLSHGSNPRLVDDDGMTSLHKAAEKGHEDICSLLLQHSPALKAVRDHKARLACDLLPCNSGLRDLLAS", "length": 186 }, "evidence": [ { "id": "A9C3P2", "url": "https://omabrowser.org/oma/group/A9C3P2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q53RE8-1", "protein_name": "Ankyrin repeat domain-containing protein 39", "gene_name": "ANKRD39", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPRPCADGPCCSHPSAVLGVQQTLEEMDFERGIWSAALNGDLGRVKHLIQKAEDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTEIARLLLSHGSNPRVVDDDGMTSLHKAAERGHGDICSLLLQHSPALKAIRDRKARLACDLLPCNSDLRDLLSS", "length": 183 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-081104-153", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-153#orthology", "database": "AGR" }, { "id": "HGNC:28640", "url": "https://alliancegenome.org/gene/HGNC:28640#orthology", "database": "AGR" }, { "id": "RGD:1559504", "url": "https://alliancegenome.org/gene/RGD:1559504#orthology", "database": "AGR" }, { "id": "MGI:1914816", "url": "https://alliancegenome.org/gene/MGI:1914816#orthology", "database": "AGR" }, { "id": "FB:FBgn0264743", "url": "https://alliancegenome.org/gene/FB:FBgn0264743#orthology", "database": "AGR" }, { "id": "A9C3P2", "url": "https://omabrowser.org/oma/group/A9C3P2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q54KH3-1", "protein_name": "Ankyrin repeat domain-containing protein 39 homolog", "gene_name": "ankrd39", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MDKHHNHECNGHECNHVQVDSVTQSLDELNFERGIWGSIINSDFKKVEQLLYKNSSLSNTMDSSGYYPLHYAVRNDKNNDIVQLLLDNGANINCQTSGGATPLHRSCFCNSINNTKLLLKKGITKVDLIDSDGMTPLHKAYQQGNMEIVNLLLQFGADPNILDKNKMKPIQLLK", "length": 174 }, "evidence": [ { "id": "A9C3P2", "url": "https://omabrowser.org/oma/group/A9C3P2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q7KTP7-1", "protein_name": "Ankyrin repeat domain-containing protein 39", "gene_name": "CG5822", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDPHSADNCKCHKQTQPAQQTLSDMDFDRGIWNAAIYNEVERVREFIKKGQSMARDDCDYTALHYAARNGNEPICKLLLDEGKADVNAVTKAGATALHRAAMMGHLEIVKLLVEHKANLLLQDESGQTALHRAVMRGHLEVCRILLAKEPTLKLVKDKKDKIAFEYIMENANDDFKLLLKP", "length": 181 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-081104-153", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-153#orthology", "database": "AGR" }, { "id": "HGNC:28640", "url": "https://alliancegenome.org/gene/HGNC:28640#orthology", "database": "AGR" }, { "id": "RGD:1559504", "url": "https://alliancegenome.org/gene/RGD:1559504#orthology", "database": "AGR" }, { "id": "MGI:1914816", "url": "https://alliancegenome.org/gene/MGI:1914816#orthology", "database": "AGR" }, { "id": "FB:FBgn0264743", "url": "https://alliancegenome.org/gene/FB:FBgn0264743#orthology", "database": "AGR" }, { "id": "A9C3P2", "url": "https://omabrowser.org/oma/group/A9C3P2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9D2X0-1", "protein_name": "Ankyrin repeat domain-containing protein 39", "gene_name": "Ankrd39", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAPHLCADGSCCSHPSAVPGVQQTLEEMDFDRGIWSAALNGDLGRVKYFIQKATDPSQPDSAGYTALHYASRNGHYAVCQFLLESGAKCDAQTHGGATALHRASYCGHTEIARLLLSHGSNPWLVDNDGMTSLHKAAEKGHEDICSLLLQHSPALKAVRDRKARLACDLLPCNSGLWDLLAS", "length": 183 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-081104-153", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-153#orthology", "database": "AGR" }, { "id": "HGNC:28640", "url": "https://alliancegenome.org/gene/HGNC:28640#orthology", "database": "AGR" }, { "id": "RGD:1559504", "url": "https://alliancegenome.org/gene/RGD:1559504#orthology", "database": "AGR" }, { "id": "MGI:1914816", "url": "https://alliancegenome.org/gene/MGI:1914816#orthology", "database": "AGR" }, { "id": "FB:FBgn0264743", "url": "https://alliancegenome.org/gene/FB:FBgn0264743#orthology", "database": "AGR" }, { "id": "A9C3P2", "url": "https://omabrowser.org/oma/group/A9C3P2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 61, "end_pos": 63, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 61, "end_pos": 63 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", 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"A9C3S8_DANRE", "mass": { "chemical_mass": 17453.0, "monoisotopic_mass": 17453.0 }, "refseq": { "ac": "NP_001121707", "name": "uncharacterized protein LOC556245", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121707" }, "gene_names": [ { "name": "si:dkey-20d21.12", "type": "recommended", "evidence": [ { "id": "A9C3S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9C3S8" } ] }, { "name": "si:dkey-20d21.12", "type": "synonym", "evidence": [ { "id": "NP_001121707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121707" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC556245", "type": "synonym", "evidence": [ { "id": "A9C3S8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9C3S8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC556245", "type": "synonym", "evidence": [ { "id": "NP_001121707", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121707" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH497541.1, GFIL01037037.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000008.1. On Jul 31, 2008 this sequence version replaced XP_684090.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001121707", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121707" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9C3S8", "url": "https://www.uniprot.org/uniprotkb/A9C3S8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-20d21.12", "url": "https://www.uniprot.org/uniprotkb/A9C3S8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-365", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-365", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092123", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092123", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "556245", "url": "https://www.ncbi.nlm.nih.gov/gene/556245", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:556245", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556245", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SHKMRPP", "url": "https://omabrowser.org/oma/group/SHKMRPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A9C3S8", "url": "https://www.orthodb.org/?gene=A9C3S8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001121707", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121707", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A9C3S8", "url": "https://www.uniprot.org/uniprotkb/A9C3S8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A9C3S8-1", "url": "https://www.uniprot.org/uniprotkb/A9C3S8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-365", "url": "https://zfin.org/ZDB-GENE-081104-365", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNSTSPPPAFVRVSERDLTEIELYSVDSINDLHRTHSEQHSKGVQPPRPPPPSTNGNLQMQDRPVVYQTGQADRRPCVSRLNHILTSTRRNYFLTCAVITAFLLTLILIFSFLVQQSRALHILTEMVKQERETVEDIAQLLKRHINLTEQRP", "length": 152, "header": "tr|A9C3S8-1|A9C3S8_DANRE Isoform 1 of Uncharacterized protein LOC556245 OS=Danio rerio OX=7955 GN=si:dkey-20d21.12 PE=4 SV=1 CANONICAL=A9C3S8-1" }, "isoforms": [ { "isoform_ac": "A9C3S8-1", "url": "https://www.uniprot.org/uniprotkb/A9C3S8/entry#A9C3S8-1", "sequence": { "sequence": "MNSTSPPPAFVRVSERDLTEIELYSVDSINDLHRTHSEQHSKGVQPPRPPPPSTNGNLQMQDRPVVYQTGQADRRPCVSRLNHILTSTRRNYFLTCAVITAFLLTLILIFSFLVQQSRALHILTEMVKQERETVEDIAQLLKRHINLTEQRP", "length": 152, "header": "tr|A9C3S8-1|A9C3S8_DANRE Isoform 1 of Uncharacterized protein LOC556245 OS=Danio rerio OX=7955 GN=si:dkey-20d21.12 PE=4 SV=1 CANONICAL=A9C3S8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A9C3S8", "url": "https://www.uniprot.org/uniprotkb/A9C3S8" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:556245", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556245", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2, "end_pos": 4, "annotation": 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"total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A9C461-1", "uniprot_ac": "A9C461", "uniprot_id": "A9C461_DANRE", "mass": { "chemical_mass": 31095.0, "monoisotopic_mass": 31095.0 }, "refseq": { "ac": "NP_001107113", "name": "asialoglycoprotein receptor-like 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107113" }, "gene_names": [ { "name": "asgrl1", "type": "recommended", "evidence": [ { "id": "A9C461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ] }, { "name": "asgrl1", "type": "synonym", "evidence": [ { "id": "NP_001107113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107113" } ] }, { "name": "si:ch211-170d8.5", "type": "synonym", "evidence": [ { "id": "NP_001107113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107113" }, { "id": "A9C461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ] } ], "protein_names": [ { "name": "Asialoglycoprotein receptor-like 1", "type": "synonym", "evidence": [ { "id": "A9C461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9C461/entry#names_and_taxonomy" } ] }, { "name": "asialoglycoprotein receptor-like 1", "type": "synonym", "evidence": [ { "id": "NP_001107113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107113" } ] }, { "name": "dcsign-like b", "type": "synonym", "evidence": [ { "id": "NP_001107113", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107113" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH507764.1, CK030130.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000008.1. On Jan 20, 2008 this sequence version replaced XP_001340665.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001107113", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107113" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9C461", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "asgrl1", "url": "https://www.uniprot.org/uniprotkb/A9C461", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081105-120", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-120", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000046142", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000046142", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03590", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03590", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100000463", "url": "https://www.ncbi.nlm.nih.gov/gene/100000463", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100000463", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000463", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTFWDEG", "url": "https://omabrowser.org/oma/group/PTFWDEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A9C460", "url": "https://www.orthodb.org/?gene=A9C460", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A9C461", "url": "https://www.orthodb.org/?gene=A9C461", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22803", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22803", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001107113", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107113", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A9C460", "url": "https://www.uniprot.org/uniprotkb/A9C460", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A9C460-1", "url": "https://www.uniprot.org/uniprotkb/A9C460-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A9C461", "url": "https://www.uniprot.org/uniprotkb/A9C461", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A9C461-1", "url": "https://www.uniprot.org/uniprotkb/A9C461-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081105-120", "url": "https://zfin.org/ZDB-GENE-081105-120", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKTAIRTLTAADEQKSPHKLTLYNMETVSYDRFTSAETEINHSGQKFIMQSDCFLFPSTGRRNRMIYIIYAILALYVFILTLAVGIKISQISQEVADVRLYMKTFVDAPKTPQFENGHFSELVMQVPVAEQGPCQENWVFYKGSCYFQSTMKRNWKTAESNCIQKGSHLVVVNDLAELDFLSSIVKLSDSYWIGLVEKEEGQWSWVDGTEFSATEHHWDVGQPDDWDVRVNGEDCGQLHSREIVNRRRMWNDADCTLSYPYICEGNPKSH", "length": 270, "header": "tr|A9C461-1|A9C461_DANRE Isoform 1 of Asialoglycoprotein receptor-like 1 OS=Danio rerio OX=7955 GN=asgrl1 PE=4 SV=1 CANONICAL=A9C461-1" }, "isoforms": [ { "isoform_ac": "A9C460-1", "url": "https://www.uniprot.org/uniprotkb/A9C461/entry#A9C460-1", "sequence": { "sequence": "MKTAIRTLTAADEQKSPHKLTLYNMETVSYDRFTSAETEINHSGQKFIMQSGRRNRMIYIIYAILALYVFILTLAVGIKISQISQEVADVRLYMKTFVDAPKTPQFENGHFSELVMQVPVAEQGPCQENWVFYKGSCYFQSTMKRNWKTAESNCIQKGSHLVVVNDLAELDFLSSIVKLSDSYWIGLVEKEEGQWSWVDGTEFSATEHHWDVGQPDDWDVRVNGEDCGQLHSREIVNRRRMWNDADCTLSYPYICEGNPKSH", "length": 262, "header": "tr|A9C460-1|A9C461_DANRE Computationally mapped isoform of Asialoglycoprotein receptor-like 1 OS=Danio rerio OX=7955 GN=asgrl1 PE=4 SV=1 CANONICAL=A9C461-1" }, "locus": {} }, { "isoform_ac": "A9C461-1", "url": "https://www.uniprot.org/uniprotkb/A9C461/entry#A9C461-1", "sequence": { "sequence": "MKTAIRTLTAADEQKSPHKLTLYNMETVSYDRFTSAETEINHSGQKFIMQSDCFLFPSTGRRNRMIYIIYAILALYVFILTLAVGIKISQISQEVADVRLYMKTFVDAPKTPQFENGHFSELVMQVPVAEQGPCQENWVFYKGSCYFQSTMKRNWKTAESNCIQKGSHLVVVNDLAELDFLSSIVKLSDSYWIGLVEKEEGQWSWVDGTEFSATEHHWDVGQPDDWDVRVNGEDCGQLHSREIVNRRRMWNDADCTLSYPYICEGNPKSH", "length": 270, "header": "tr|A9C461-1|A9C461_DANRE Isoform 1 of Asialoglycoprotein receptor-like 1 OS=Danio rerio OX=7955 GN=asgrl1 PE=4 SV=1 CANONICAL=A9C461-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A9C461", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "The hepatic lectin of zebrafish binds a wide range of bacteria and participates in immune defense.", "journal": "Fish Shellfish Immunol.", "date": "2018", "authors": "Yang Qingyun, Wang Peng, Wang Su, Wang Yashuo, Feng Shuoqi, Zhang Shicui, Li Hongyan", "evidence": [ { "database": "UniProtKB", "id": "A9C461", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ], "reference": [ { "type": "PubMed", "id": "30120977", "url": "https://glygen.org/publication/PubMed/30120977" } ] }, { "title": "Studies Into beta-Glucan Recognition in Fish Suggests a Key Role for the C-Type Lectin Pathway.", "journal": "Front. Immunol.", "date": "2019", "authors": "Petit Jules, Bailey Erin C, Wheeler Robert T, de Oliveira Carlos A F, Forlenza Maria, Wiegertjes Geert F", "evidence": [ { "database": "UniProtKB", "id": "A9C461", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ], "reference": [ { "type": "PubMed", "id": "30863400", "url": "https://glygen.org/publication/PubMed/30863400" } ] }, { "title": "A novel hepatic lectin of zebrafish Danio rerio is involved in innate immune defense.", "journal": "Fish Shellfish Immunol.", "date": "2020", "authors": "Yang Qingyun, Wang Peng, Yang Shuaiqi, Li Xianpeng, Zhang Xiangmin, Ji Guangdong, Zhang Shicui, Wang Su, Li Hongyan", "evidence": [ { "database": "UniProtKB", "id": "A9C461", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ], "reference": [ { "type": "PubMed", "id": "31689552", "url": "https://glygen.org/publication/PubMed/31689552" } ] }, { "title": "Low Molecular Weight Fucoidan Prevents Radiation-Induced Fibrosis and Secondary Tumors in a Zebrafish Model.", "journal": "Cancers", "date": "2020", "authors": "Wu Szu-Yuan, Yang Wan-Yu, Cheng Chun-Chia, Hsiao Ming-Chen, Tsai Shin-Lin, Lin Hua-Kuo, Lin Kuan-Hao, Yuh Chiou-Hwa", "evidence": [ { "database": "UniProtKB", "id": "A9C461", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ], "reference": [ { "type": "PubMed", "id": "32570707", "url": "https://glygen.org/publication/PubMed/32570707" } ] }, { "title": "Low molecular weight fucoidan inhibits hepatocarcinogenesis and nonalcoholic fatty liver disease in zebrafish via ASGR/STAT3/HNF4A signaling.", "journal": "Clin. Transl. Med.", "date": "2020", "authors": "Wu Szu-Yuan, Yang Wan-Yu, Cheng Chun-Chia, Lin Kuan-Hao, Sampurna Bonifasius Putera, Chan Suat-Ming, Yuh Chiou-Hwa", "evidence": [ { "database": "UniProtKB", "id": "A9C461", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ], "reference": [ { "type": "PubMed", "id": "33377648", "url": "https://glygen.org/publication/PubMed/33377648" } ] } ], "pathway": [ { "id": "dre:100000463", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000463", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32TVV3-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "asgr1c.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRRGWSLFFNFKNQPLILVPLFLLSQNMEMHSSEEYMKMEVECETKQSLCKGRPCSKQTGILVLLGTVGMIIFLVLISIIVQAKKLSDIETLMTDLSSSLDSLTSKHEENQQKLERQQNVSYIQVKKQMDTVRASVSSIMSKLKADSVRTSFMFRHPLERFLIEHSSEELESGCSDSAWVPFGNSCYLFSRDKMNWTEAKDYCEEKGAWLLKIEDDSEDEWQFVTDFANPTHYWIGLTDQNTGQWRWADGTNYTMNKEHWGPGQPDEWTEHSLGEEGEDCAEITYESLLNDLHCSSKIKFICEMKT", "length": 306 }, "evidence": [ { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" }, { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" }, { "id": "HGNC:743", "url": "https://alliancegenome.org/gene/HGNC:743#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B7Z0K3-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG14866", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPAGQQLRLTALVYLALGIALLCNGSDGETRQKYANESLADADDPSPVWSQFLEDYVLSQGSSSSGSQRKSKDLPYMGADMGINGPLSYHSSAYKRPGNNIYITRRIGEAVELEPHLRKPVESQSPIVNPQFRPMTNQMLHQQHQQMQQQQQQQQLQQRQQPGFLQQLFGIGGSGGGGGSGTQQQQHVRPVPLQQQQVQQIAQQHPQQQHLVGGQPTTFRAVSENDLYLLGAIEKLVYRVDYLESRVRRSEQLIYYLMAGNNQKEVKDPCPANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAEFEKVSENEEIMAYLLNQPTHRGRDYWLGGLNPGLLWIWSNSAKPVNPNMNLTSIAMAQKGENSTAANLVDSSEQAAEEATGEDVLNNTVQIEGKGRCLRLSYNAGKHSYVYYGQECTSRHYYICEHEDKTLDNKIKKITRELKLFE", "length": 455 }, "evidence": [ { "id": "HGNC:742", "url": "https://alliancegenome.org/gene/HGNC:742#orthology", "database": "AGR" }, { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" }, { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "F8W3Q0-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "asgr1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRVVSSDSGSVTVANTEYTDETESAETSDHTEFWRGDPSVRRLAAVPSGGRWRWCAGIAGSVAALMLLLLIITVSVNHVKFNRKFSATEVRIQNLTQIILNVISRTQELEQFGHKINADVSSLEFDQRMTETSMNNLLESAQALHDKVSELKCHIDKMRNNNTQELCCPDQWSLFSSNCYFFSTDGMSWDSARDECERKRAKLLILTSKLEKSFVVSKTKPLFYWLGLTDGRTGEWEWLDETPYEMVRSEWRPGQPDNWKAHGLGGGEDCAHFHHDGRYNDDHCSRHYRYICKAAASAI", "length": 299 }, "evidence": [ { "id": "HGNC:742", "url": "https://alliancegenome.org/gene/HGNC:742#orthology", "database": "AGR" }, { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" }, { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" }, { "id": "HGNC:743", "url": "https://alliancegenome.org/gene/HGNC:743#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P02706-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "Asgr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTKDYQDFQHLDNENDHHQLQRGPPPAPRLLQRLCSGFRLFLLSLGLSILLLVVVCVITSQNSQLREDLRVLRQNFSNFTVSTEDQVKALTTQGERVGRKMKLVESQLEKHQEDLREDHSRLLLHVKQLVSDVRSLSCQMAALRGNGSERICCPINWVEYEGSCYWFSSSVKPWTEADKYCQLENAHLVVVTSWEEQRFVQQHMGPLNTWIGLTDQNGPWKWVDGTDYETGFKNWRPGQPDDWYGHGLGGGEDCAHFTTDGHWNDDVCRRPYRWVCETELGKAN", "length": 284 }, "evidence": [ { "id": "HGNC:742", "url": "https://alliancegenome.org/gene/HGNC:742#orthology", "database": "AGR" }, { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P07306-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "ASGR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTKEYQDLQHLDNEESDHHQLRKGPPPPQPLLQRLCSGPRLLLLSLGLSLLLLVVVCVIGSQNSQLQEELRGLRETFSNFTASTEAQVKGLSTQGGNVGRKMKSLESQLEKQQKDLSEDHSSLLLHVKQFVSDLRSLSCQMAALQGNGSERTCCPVNWVEHERSCYWFSRSGKAWADADNYCRLEDAHLVVVTSWEEQKFVQHHIGPVNTWMGLHDQNGPWKWVDGTDYETGFKNWRPEQPDDWYGHGLGGGEDCAHFTDDGRWNDDVCQRPYRWVCETELDKASQEPPLL", "length": 291 }, "evidence": [ { "id": "HGNC:742", "url": "https://alliancegenome.org/gene/HGNC:742#orthology", "database": "AGR" }, { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081105-120", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-120#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P07307-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "ASGR2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKDFQDIQQLSSEENDHPFHQGEGPGTRRLNPRRGNPFLKGPPPAQPLAQRLCSMVCFSLLALSFNILLLVVICVTGSQSEGHGGAQLQAELRSLKEAFSNFSSSTLTEVQAISTHGGSVGDKITSLGAKLEKQQQDLKADHDALLFHLKHFPVDLRFVACQMELLHSNGSQRTCCPVNWVEHQGSCYWFSHSGKAWAEAEKYCQLENAHLVVINSWEEQKFIVQHTNPFNTWIGLTDSDGSWKWVDGTDYRHNYKNWAVTQPDNWHGHELGGSEDCVEVQPDGRWNDDFCLQVYRWVCEKRRNATGEVA", "length": 311 }, "evidence": [ { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" }, { "id": "HGNC:743", "url": "https://alliancegenome.org/gene/HGNC:743#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081105-120", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-120#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P08290-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "Asgr2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKDFQDIQQLDSEENDHQLIGDEEQGSHVQNLRTENPRWGGQPPSRPFPQRLCSKFRLSLLALAFNILLLVVICVVSSQSMQLQKEFWTLKETLSNFSTTTLMEFKALDSHGGSRNDNLTSWETILEKKQKDIKADHSTLLFHLKHFPLDLRTLTCQLAFFLSNGTECCPVNWVEFGGSCYWFSRDGLTWAEADQYCQMENAHLLVINSREEQEFVVKHRGAFHIWIGLTDKDGSWKWVDGTEYRSNFKNWAFTQPDNWQGHEEGGSEDCAEILSDGLWNDNFCQQVNRWACERKRDITY", "length": 301 }, "evidence": [ { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" }, { "id": "HGNC:743", "url": "https://alliancegenome.org/gene/HGNC:743#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P24721-1", "protein_name": "Asialoglycoprotein receptor 2", "gene_name": "Asgr2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKDCQDIQQLDSEENDHQLSGDDEHGSHVQDPRIENPHWKGQPLSRPFPQRLCSTFRLSLLALAFNILLLVVICVVSSQSIQLQEEFRTLKETFSNFSSSTLMEFGALDTLGGSTNAILTSWLAQLEEKQQQLKADHSTLLFHLKHFPMDLRTLTCQLAYFQSNGTECCPVNWVEFGGSCYWFSRDGLTWAEADQYCQLENAHLLVINSREEQDFVVKHRSQFHIWIGLTDRDGSWKWVDGTDYRSNYRNWAFTQPDNWQGHEQGGGEDCAEILSDGHWNDNFCQQVNRWVCEKRRNITH", "length": 301 }, "evidence": [ { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" }, { "id": "HGNC:743", "url": "https://alliancegenome.org/gene/HGNC:743#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081105-120", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-120#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P34927-1", "protein_name": "Asialoglycoprotein receptor 1", "gene_name": "Asgr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTKDYQDFQHLDNDNDHHQLRRGPPPTPRLLQRLCSGSRLLLLSSSLSILLLVVVCVITSQNSQLREDLLALRQNFSNLTVSTEDQVKALSTQGSSVGRKMKLVESKLEKQQKDLTEDHSSLLLHVKQLVSDVRSLSCQMAAFRGNGSERTCCPINWVEYEGSCYWFSSSVRPWTEADKYCQLENAHLVVVTSRDEQNFLQRHMGPLNTWIGLTDQNGPWKWVDGTDYETGFQNWRPEQPDNWYGHGLGGGEDCAHFTTDGRWNDDVCRRPYRWVCETKLDKAN", "length": 284 }, "evidence": [ { "id": "HGNC:742", "url": "https://alliancegenome.org/gene/HGNC:742#orthology", "database": "AGR" }, { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081105-120", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-120#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IRH8-1", "protein_name": "Triforce, isoform B", "gene_name": "tfc", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MIRPTLIVVLISLASVDSGHNSPVTTIPVAEPISQVPHGFQLGQNNHISSSSNISRSGGGNGRDKRGAQLDPSEIARQNQITQQIFANYLERRLFPNRTANQKIPTIADILPKPKPSPRPRPRGFAASDGGNFKRSGGGAQRNRLAAAASKRQSGYNRKRLREEQEEEEEADDQERDQQPLANQEDFDYDVQESLQSVESEQHDQYYGNIFHRDPSENEVDNDCPNCVDESQYTPNKWTMPLLKLGEKRYYLGIFFKANWFKATQYCRYHGMHLASISSQEENDRLEKHIRDFGLGHEHFWISGTDLADEGNFFWMATGRPITFTNWNAGEPNNFRYENGEEENCLELWNRDGKGLKWNDSPCSFETYFVCEVQPN", "length": 376 }, "evidence": [ { "id": "HGNC:742", "url": "https://alliancegenome.org/gene/HGNC:742#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQU4-1", "protein_name": "Lectin-24A", "gene_name": "lectin-24A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFRLSVLVLNLLLVSHEFSAGTAKIEIQPLPALCNGYCFPTLKPVMEYVAIHQDKWNTCTEILANEARKDQIQLNIQLDALKADVSNIKASQLSKDEKLDRMEREQFAMHESLETINRYLTVKLDRTKLQLEAIKNTMDYMKAQMDGYFSAINGVQCLQPGFEKIGDRYFYIEEDVELNWLDAQAKCRRMGGHLASIKTKQEFDAIVEKLDDSKSYFLGVNENTKTGDFVSAASGKSCLYHEWGPGEPHHNNDQERCVSILRKLMHVGNCTYEKRFICQYGI", "length": 282 }, "evidence": [ { "id": "MGI:88082", "url": "https://alliancegenome.org/gene/MGI:88082#orthology", "database": "AGR" }, { "id": "MGI:88081", "url": "https://alliancegenome.org/gene/MGI:88081#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQX3-1", "protein_name": "Lectin-24Db", "gene_name": "lectin-24Db", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFRLEKCIVYLLVACNLVESRAESTENSRSVCLLKDPPNQCGEFCLSVLQPLLDHIVKHQEQWNTSEALWLNETQGKLDRIQTQLAAQALSLEESAQKVPGDIKDRLDRMEHLQTTLQESLKKMPAELDARLMKMENQQKTLGDQLENQINLTKESQQDQLEALKNAMPINFEMRLAQIEEQQKLLQETLKKIPEDFERKLQKLEQNQKDELTKLGAQQSANQVTLKEIYTKVFWPKFERIGSRLFYINHKDAYDWQSAVDFCRDMGGYIAAIKDQEELDAISARLDDKSYWLGINDLQSSNTYVSVASGREVEFLNWNAGEPNHGNEDENCVELIRSKMNDDPCHRKKHVICQTDKEV", "length": 359 }, "evidence": [ { "id": "HGNC:743", "url": "https://alliancegenome.org/gene/HGNC:743#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "A9C461", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "A9C461", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "A9C461", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "A9C461", "url": "https://www.uniprot.org/uniprotkb/A9C461" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "A9C461", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9C461" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 141, "end_pos": 264, "start_aa": "Tyr", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "A9JRA0-1", "uniprot_ac": "A9JRA0", "uniprot_id": "ST7L_DANRE", "mass": { "chemical_mass": 61283.0, "monoisotopic_mass": 61283.0 }, "refseq": { "ac": "NP_001104626", "name": "suppressor of tumorigenicity 7 protein-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104626" }, "gene_names": [ { "name": "st7l", "type": "recommended", "evidence": [ { "id": "A9JRA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9JRA0" } ] }, { "name": "st7l", "type": "synonym", "evidence": [ { "id": "NP_001104626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104626" } ] }, { "name": "zgc:172009", "type": "synonym", "evidence": [ { "id": "NP_001104626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104626" }, { "id": "A9JRA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9JRA0" } ] } ], "protein_names": [ { "name": "Suppressor of tumorigenicity 7 protein-like", "type": "recommended", "evidence": [ { "id": "A9JRA0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9JRA0/entry#names_and_taxonomy" } ] }, { "name": "Suppressor of tumorigenicity protein 7-like protein", "type": "synonym", "evidence": [ { "id": "NP_001104626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104626" } ] }, { "name": "suppressor of tumorigenicity 7 protein-like", "type": "synonym", "evidence": [ { "id": "NP_001104626", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104626" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC155576.1, BC115264.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC155576.1. On Dec 9, 2007 this sequence version replaced XP_686269.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001104626", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104626" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9JRA0", "url": "https://www.uniprot.org/uniprotkb/A9JRA0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "st7l", "url": "https://www.uniprot.org/uniprotkb/A9JRA0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080219-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080219-43", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A9JRA0", "url": "https://alphafold.ebi.ac.uk/entry/A9JRA0", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000032603", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000032603", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd11557", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11557", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "558013", "url": "https://www.ncbi.nlm.nih.gov/gene/558013", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558013", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558013", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDYEIMQ", "url": "https://omabrowser.org/oma/group/QDYEIMQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A9JRA0", "url": "https://www.orthodb.org/?gene=A9JRA0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12745", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12745", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12745:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12745:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04184", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04184", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A9JRA0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A9JRA0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001104626", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001104626", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58JRM1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JRM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JRM1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JRM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A9JRA0", "url": "https://www.uniprot.org/uniprotkb/A9JRA0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A9JRA0-1", "url": "https://www.uniprot.org/uniprotkb/A9JRA0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080219-43", "url": "https://zfin.org/ZDB-GENE-080219-43", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MADSSGSNPQSPGFTEKLKSWLCWSWTYICALWFAMVLTMVYVLRSPLKLQETVNAASVFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVENSGSAGLFSSVNGDAEPRSNVAECKVWRNPLNLFRGAEYSRYTWVTGKEPLTYYDMNLSAQDHQTFFLGDTQQLRPEDSVMQKAWRERNPQARIRAAYQAIELNRECAAAYVLLAEEEATTITEAERLFKQALKSAGKDTNLVVYIKRRLAMCARKLGRIKEAVKMMRDLMKEFPLLGMLNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTSALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAVAYAFFHLQHWKRAEGALNLLHCTWEGTFRIIPYPLEKGHLFYPYPGCTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFCAMLAMLTHQFPELMGVFVKAFFSTLFAPLGFFADKMESFMPSCLWHQLTNV", "length": 540, "header": "sp|A9JRA0-1|ST7L_DANRE Isoform 1 of Suppressor of tumorigenicity 7 protein-like OS=Danio rerio OX=7955 GN=st7l PE=2 SV=1 CANONICAL=A9JRA0-1" }, "isoforms": [ { "isoform_ac": "A0AC58JRM1-1", "url": "https://www.uniprot.org/uniprotkb/A9JRA0/entry#A0AC58JRM1-1", "sequence": { "sequence": "MQMQIFTRHVTAISLSWRALKRAHLIGAHRLGNLRHASVFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVENSGSAGLFSSVNGDAEPRSNVAECKVWRNPLNLFRGAEYSRYTWVTGKEPLTYYDMNLSAQDHQTFFLGDTQQLRPEDSVMQKAWRERNPQARIRAAYQAIELNRECAAAYVLLAEEEATTITEAERLFKQALKSAGKDTNLVVYIKRRLAMCARKLGRIKEAVKMMRDLMKEFPLLGMLNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTSALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAVAYAFFHLQHWKRAEGALNLLHCTWEGTFRIIPYPLEKGHLFYPYPGCTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFCAMLAMLTHQFPELMGVFVKAFFSTLFAPLGFFADKMESFMPSCLWHQLTNV", "length": 520, "header": "tr|A0AC58JRM1-1|A0AC58JRM1_DANRE Computationally mapped isoform of Suppressor of tumorigenicity 7 protein-like isoform X1 OS=Danio rerio OX=7955 GN=st7l PE=3 SV=1 CANONICAL=A9JRA0-1" }, "locus": {} }, { "isoform_ac": "A9JRA0-1", "url": "https://www.uniprot.org/uniprotkb/A9JRA0/entry#A9JRA0-1", "sequence": { "sequence": "MADSSGSNPQSPGFTEKLKSWLCWSWTYICALWFAMVLTMVYVLRSPLKLQETVNAASVFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVENSGSAGLFSSVNGDAEPRSNVAECKVWRNPLNLFRGAEYSRYTWVTGKEPLTYYDMNLSAQDHQTFFLGDTQQLRPEDSVMQKAWRERNPQARIRAAYQAIELNRECAAAYVLLAEEEATTITEAERLFKQALKSAGKDTNLVVYIKRRLAMCARKLGRIKEAVKMMRDLMKEFPLLGMLNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTSALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAVAYAFFHLQHWKRAEGALNLLHCTWEGTFRIIPYPLEKGHLFYPYPGCTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFCAMLAMLTHQFPELMGVFVKAFFSTLFAPLGFFADKMESFMPSCLWHQLTNV", "length": 540, "header": "sp|A9JRA0-1|ST7L_DANRE Isoform 1 of Suppressor of tumorigenicity 7 protein-like OS=Danio rerio OX=7955 GN=st7l PE=2 SV=1 CANONICAL=A9JRA0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:558013", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558013", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M527-1", "protein_name": "Suppressor of tumorigenicity 7 protein-like", "gene_name": "St7l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MADGEYFAEAARAVGCPHAPVPGLGLGPPLGWKERLKAGLANSGSTLWFLAGLGLLYALRVPLRLCDNVTAVTGFLSSLTPKFYVALTGTSSLISGLIFIFEWWYFHKHGTSFIEQVSISHLRPLMGGTESSISEPGSPASNRESETLRHHHLSECKVWRNPLNLFRGAEYRRYTWVTGKEPLTYYDMNLSAQDHQTFFTCETDFLRPSDTVMQKAWRERNPPARIKAAYQALELNNDCATAYVLLAEEEATTIVDAERLFKQALRAGEIIYRRSQQCQHQSPQHEAQLRRDTNVLVYIKRRLAMCARKLGRIREAVKIMRDLMKEFPPLTMLNIHENLLESLLELQAYADVQAVLAKYDDISLPKSAAICYTAALLKTRTVSDKFSPETASRRGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLQHWKRIEGALNLLQCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPTFHHVSVYPKKELPFFIHFTAGLCSSTAMIAFLTHQFPEVMAVFAKAVSMISRTCVEYL", "length": 559 }, "evidence": [ { "id": "A9JRA0", "url": "https://omabrowser.org/oma/group/A9JRA0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1RLU8-1", "protein_name": "Suppressor of tumorigenicity 7 protein homolog", "gene_name": "st7", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFGTESSLSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNSTASSSSSSSNGDADSSRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDSDHLRPADAIMQKAWRERNPQARITAAHEALDLEDCATAYILLAEEEATTIVEAEKLFKQALKVGETCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCSRKLGRTREAVKMMRDLMKEFPLLSMFNIHENLLESLLELQNYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYTFFHLQHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPVCTETADRELLPTVFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAFLSTLFAPLNFIMEKVESILPSSLWHQLTRI", "length": 513 }, "evidence": [ { "id": "FB:FBgn0037026", "url": "https://alliancegenome.org/gene/FB:FBgn0037026#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2IBD0-1", "protein_name": "Suppressor of tumorigenicity 7 protein", "gene_name": "St7", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEAGSGFLEQLKSCIVWSWTYLWTVWFFLVLFLVYILRVPLRINDNLSTVSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNNSSNNSNSSNGDSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDSDHLRPADAIMQKAWRERNPQARISAAHEALEINEIRSRVEVPLIASSTIWEIKLLPKCATAYILLAEEEATTIAEAEKLFKQALKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCARRLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAFLSTLFAPLNFVMEKVESILPSSLWHQLTRI", "length": 577 }, "evidence": [ { "id": "FB:FBgn0037026", "url": "https://alliancegenome.org/gene/FB:FBgn0037026#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FW3-1", "protein_name": "Suppressor of tumorigenicity 7 protein-like", "gene_name": "St7l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADGDYFAEAARAVGCPHAPVPGLGLGPPLGWKERLKAGLANSGSTLWFLAGLGLLYALRVPLRLCDNVTAVTGFLSSLTPKFYVALTGTSSLISGLIFIFEWWYFHKHGTSFIEQVSISHLRPLMGGTESSISEPGSPANSRESETLRHHHLSECKVWRNPLNLFRGAEYRRYTWVTGKEPLTYYDMNLSAQDHQTFFTCETDFLRPSDTVMQKAWRERNPPARIKAAYQALELNNDCATAYVLLAEEEATTIVDAERLFKQALRAGEIIYRRSQQCQHQSPQHEAQLRRDTNVLVYIKRRLAMCARKLGRIREAVKIMRDLMKEFPPLTMLNIHENLLESLLELQAYADVQAVLAKYDDISLPKSAAICYTAALLKTRTVSDKFSPETAFRKGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLQHWKRIEGALNLLQCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPTFHHVSVYPKKELPFFIHFTAGLCSSTAMIALLTHQFPEVMGVFAKAVSMISRTCVEYL", "length": 559 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080219-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080219-43#orthology", "database": "AGR" }, { "id": "HGNC:18441", "url": "https://alliancegenome.org/gene/HGNC:18441#orthology", "database": "AGR" }, { "id": "RGD:1359336", "url": "https://alliancegenome.org/gene/RGD:1359336#orthology", "database": "AGR" }, { "id": "MGI:2386964", "url": "https://alliancegenome.org/gene/MGI:2386964#orthology", "database": "AGR" }, { "id": "FB:FBgn0037026", "url": "https://alliancegenome.org/gene/FB:FBgn0037026#orthology", "database": "AGR" }, { "id": "A9JRA0", "url": "https://omabrowser.org/oma/group/A9JRA0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K4P7-1", "protein_name": "Suppressor of tumorigenicity 7 protein-like", "gene_name": "St7l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADGDYFAEAARAVGCPHAPVPGLGLGPPLGWKERLKAGLANSGSTLWFLAGLGLLYALRVPLRLCDNVTAVTGFLSSLTPKFYVALTGTSSLISGLIFIFEWWYFHKHGTSFIEQVSISHLRPLMGGTESSISEPGSPANSRESETLRHHHLSECKVWRNPLNLFRGAEYRRYTWVTGKEPLTYYDMNLSAQDHQTFFTCETDFLRPSDTVMQKAWRERNPPARIKAAYQALELNNDCATAYVLLAEEEATTIVDAERLFKQALRAGEIIYRRSQQCQHQSPQHEAQLRRDTNVLVYIKRRLAMCARKLGRIREAVKIMRDLMKEFPPLTMLNIHENLLESLLELQAYADVQAVLAKYDDISLPKSAAICYTAALLKTRTVSDKFSPETAFRKGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLQHWKRIEGALNLLQCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPTFHHVSVYPKKELPFFIHFTAGLCSSTAMLAFLTHQFPEVMGVFAKAVSMISRTCVEYL", "length": 559 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080219-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080219-43#orthology", "database": "AGR" }, { "id": "HGNC:18441", "url": "https://alliancegenome.org/gene/HGNC:18441#orthology", "database": "AGR" }, { "id": "RGD:1359336", "url": "https://alliancegenome.org/gene/RGD:1359336#orthology", "database": "AGR" }, { "id": "MGI:2386964", "url": "https://alliancegenome.org/gene/MGI:2386964#orthology", "database": "AGR" }, { "id": "FB:FBgn0037026", "url": "https://alliancegenome.org/gene/FB:FBgn0037026#orthology", "database": "AGR" }, { "id": "A9JRA0", "url": "https://omabrowser.org/oma/group/A9JRA0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8TDW4-1", "protein_name": "Suppressor of tumorigenicity 7 protein-like", "gene_name": "ST7L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADRGGVGEAAAVGASPASVPGLNPTLGWRERLRAGLAGTGASLWFVAGLGLLYALRIPLRLCENLAAVTVFLNSLTPKFYVALTGTSSLISGLIFIFEWWYFHKHGTSFIEQVSVSHLQPLMGGTESSISEPGSPSRNRENETSRQNLSECKVWRNPLNLFRGAEYRRYTWVTGKEPLTYYDMNLSAQDHQTFFTCDTDFLRPSDTVMQKAWRERNPPARIKAAYQALELNNDCATAYVLLAEEEATTIVDAERLFKQALKAGETIYRQSQQCQHQSPQHEAQLRRDTNVLVYIKRRLAMCARKLGRIREAVKIMRDLMKEFPPLTMLNIHENLLESLLELQAYPDVQAVLAKYDDISLPKSAAICYTAALLKTRTVSEKFSPETASRRGLSTAEINAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLQHWKRIEGALNLLQCTWEGTFRMIPYPLEKGHLFYPYPSCTETADRELLPTFHHVSVYPKKELPLFIHFTAGFCSSTAMIAILTHQFPEIMGIFAKAVLGLWCPQPWASSGFEENTQDLKSEDLGLSSG", "length": 575 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080219-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080219-43#orthology", "database": "AGR" }, { "id": "HGNC:18441", "url": "https://alliancegenome.org/gene/HGNC:18441#orthology", "database": "AGR" }, { "id": "RGD:1359336", "url": "https://alliancegenome.org/gene/RGD:1359336#orthology", "database": "AGR" }, { "id": "MGI:2386964", "url": "https://alliancegenome.org/gene/MGI:2386964#orthology", "database": "AGR" }, { "id": "FB:FBgn0037026", "url": "https://alliancegenome.org/gene/FB:FBgn0037026#orthology", "database": "AGR" }, { "id": "A9JRA0", "url": "https://omabrowser.org/oma/group/A9JRA0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99M96-1", "protein_name": "Suppressor of tumorigenicity 7 protein", "gene_name": "St7", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEAGAGFLEQLKSCIVWSWTYLWTVWFFLVLFLVYILRVPLRINDNLSTVSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNNSSNNSNSSNGDSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDSDHLRPADAIMQKAWRERNPQARISAAHEALEINEIRSRVEVPLIASSTIWEIKLLPKCATAYILLAEEEATTIAEAEKLFKQALKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCARRLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAFLSTLFAPLNFVMEKVESILPSSLWHQLTRI", "length": 577 }, "evidence": [ { "id": "FB:FBgn0037026", "url": "https://alliancegenome.org/gene/FB:FBgn0037026#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NRC1-1", "protein_name": "Suppressor of tumorigenicity 7 protein", "gene_name": "ST7", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEAATGFLEQLKSCIVWSWTYLWTVWFFIVLFLVYILRVPLKINDNLSTVSMFLNTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSVSHLRPLLGGVDNNSSNNSNSSNGDSDSNRQSVSECKVWRNPLNLFRGAEYNRYTWVTGREPLTYYDMNLSAQDHQTFFTCDSDHLRPADAIMQKAWRERNPQARISAAHEALEINEIRSRVEVPLIASSTIWEIKLLPKCATAYILLAEEEATTIAEAEKLFKQALKAGDGCYRRSQQLQHHGSQYEAQHRRDTNVLVYIKRRLAMCARRLGRTREAVKMMRDLMKEFPLLSMFNIHENLLEALLELQAYADVQAVLAKYDDISLPKSATICYTAALLKARAVSDKFSPEAASRRGLSTAEMNAVEAIHRAVEFNPHVPKYLLEMKSLILPPEHILKRGDSEAIAYAFFHLAHWKRVEGALNLLHCTWEGTFRMIPYPLEKGHLFYPYPICTETADRELLPSFHEVSVYPKKELPFFILFTAGLCSFTAMLALLTHQFPELMGVFAKAMIDIFCSAEFRDWNCKSIFMRVEDELEIPPAPQSQHFQN", "length": 585 }, "evidence": [ { "id": "FB:FBgn0037026", "url": "https://alliancegenome.org/gene/FB:FBgn0037026#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VPB1-1", "protein_name": "Protein ST7 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWDSSMFLSTLTPKFYVALTGTSSLISGLILIFEWWYFRKYGTSFIEQVSINHISPWINGSDGQSESSNGSGSSSSSGSSSSSNGGAGGGGSGGAGASGSGSATTSTGTQMPECKVWRNPLNLFRGAEYQRFFWATSKEPLTYYDMNLSAQDHQTFFTCEGDARKEEYEIMQTAWRERNPMQRIKSAHSALEINAECAPAYILLAEEEAMTIMEAEKILKTALKVAEINYRKSQATQHQGAIADGMHRRDTNVLIYIKRRLAMCARKLGKLKEAAKMFRDLTKEIPSIMSVLNIHENLIETLLEMQAYADCHAILAKYDDISLPKSATICYTAALLKARAVADKFSPDIASKRGLSQAEMSAVEAIHRAVEFNPHVPKYLLETKRLILPPEHILKRGDSEALAYAFFHLKHWKQVEGALNLLHCTWEGTFRMLPYPLERGHLFYPYPTCTECADRELLPAFHEVSVYPKKELPFFILFTAGLCSITALLALATHQYPEPMGHLAQTVLTWISYPFQLLKERIEAFWPCNLLQQLSRV", "length": 537 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-080219-43", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080219-43#orthology", "database": "AGR" }, { "id": "HGNC:18441", "url": "https://alliancegenome.org/gene/HGNC:18441#orthology", "database": "AGR" }, { "id": "RGD:1359336", "url": "https://alliancegenome.org/gene/RGD:1359336#orthology", "database": "AGR" }, { "id": "MGI:2386964", "url": "https://alliancegenome.org/gene/MGI:2386964#orthology", "database": "AGR" }, { "id": "FB:FBgn0037026", "url": "https://alliancegenome.org/gene/FB:FBgn0037026#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "A9JRA0", "url": "https://www.uniprot.org/uniprotkb/A9JRA0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 172, "end_pos": 174 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "A9JRI0-1", "uniprot_ac": "A9JRI0", "uniprot_id": "HEAT6_DANRE", "mass": { "chemical_mass": 130503.0, "monoisotopic_mass": 130503.0 }, "refseq": { "ac": "NP_001107785", "name": "HEAT repeat-containing protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107785" }, "gene_names": [ { "name": "heatr6", "type": "recommended", "evidence": [ { "id": "A9JRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9JRI0" } ] }, { "name": "heatr6", "type": "synonym", "evidence": [ { "id": "NP_001107785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107785" } ] }, { "name": "zgc:172359", "type": "synonym", "evidence": [ { "id": "NP_001107785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107785" }, { "id": "A9JRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9JRI0" } ] } ], "protein_names": [ { "name": "HEAT repeat-containing protein 6", "type": "recommended", "evidence": [ { "id": "A9JRI0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A9JRI0/entry#names_and_taxonomy" } ] }, { "name": "HEAT repeat-containing protein 6", "type": "synonym", "evidence": [ { "id": "NP_001107785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107785" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC155667.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476755, SAMEA4476763 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC155667.1. On Feb 6, 2008 this sequence version replaced XP_696235.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001107785", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107785" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "A9JRI0", "url": "https://www.uniprot.org/uniprotkb/A9JRI0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "heatr6", "url": "https://www.uniprot.org/uniprotkb/A9JRI0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080204-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-118", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "A9JRI0", "url": "https://alphafold.ebi.ac.uk/entry/A9JRI0", "database": "AlphaFoldDB", "categories": [] }, { "id": "567838", "url": "https://www.ncbi.nlm.nih.gov/gene/567838", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052107", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052107", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567838", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567838", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A9JRI0", "url": "https://www.orthodb.org/?gene=A9JRI0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13366", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13366", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13366:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13366:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13251", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13251", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13513", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13513", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:A9JRI0", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:A9JRI0", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001107785", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001107785", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A9JRI0", "url": "https://www.uniprot.org/uniprotkb/A9JRI0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A9JRI0-1", "url": "https://www.uniprot.org/uniprotkb/A9JRI0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080204-118", "url": "https://zfin.org/ZDB-GENE-080204-118", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAGKVTFLGSNSSFSPDGKTQGFKSASADTSRFVSLSKPQHELDGSAQAQISRCFNKLRSLSPSDSASLKTELNLLFDELISENYSSSNHDNIPPEVVCEILVQASRLVPLSQEHLIIKLCQMIHQLLNQLQIIVDEHTLDVLVSYCSRALRTCSSWTHSEVLLALSSLVYGNGSKCQRYLPDLLGPSGVLVKYGDPKQPDIELRRSAVHCIANLCLSVPSQPYLEEPYKSVCYGILLRTLQSTKPPDVDDIVFCTLLQSALKGMQYFLNGGKWKAVPNQDLGALLAVLKRFMFYGLPGISVEMPQVLYPAPLPQYETIPAVKPEPAQDTPAQKKTAASQQKKRKSRGKGKKGAGEGKQDGEADDVSAAGGGDQSGWSHGSQSSMLTSPSVATPQLYPSWKKCSSDSEFSDPEGGMQSKLRLYQARVRQSSLQCFLAVVKCVEKRILYGYWSSFVPDAPGIGGPPPLTLLTIALKDPLPKVRAGSLQVLSALLEGSRQFLSTAEDTGAPRQAFTPFSATLAASIRELHRGLLLALIAESSCQTLTQVLKCLAHLVSNVPYNRLRPGLLSPLWKQIRPYVRHRDVNVRVSSLTLFGALVSTQAPLPEVQLLLQQPGSASSLGSGISTPQESPLSWRQPARRDEEASSPAAAEGPEGPCWLLQLCVSLVTQPREEPYSDSDAGGSNGAPLEPSPVRLEALQVLAHLVKGYFSLAQASLLELGQLSARCLTEQDPSVQLHGAKLLEELGTGIIQQYRADANTPQSAKRVPVNQVVQFWSEVLGGPLISALQNEHHPTLQTSACDTLSSILPQAFSQLPDKTQVLCITILLGLTYSENSLVKAAAVRALGVYILFPCLREDVMFVADTANAILTALDDRSPNVRAKAAWSLGNLTDTLIVNMQSVGLEFQEDFSDMLLLNMLRSATKASADKDRVKSNAVRALGNLLHFLQPGHLGKPVFEQPLLEAMRALIDTVRGDATMKVRWNACYALGNAFRNQHLPLGSAVWSTEAFSALSCVVTSCKNFKVRIKSAAALSVPATRECYGDSQQFSEVWRSLAQALEHSEETEDFLEYRYCASLRSQLCRALLHLLSLCQPDDLPALGSSVSGQSRPALQALLISHLRDEGLVPSAGADGEEALDHSTPEDGWTLLTDTLTRLKGLLGEPVMDSNEDLESVLSFLQDVVRNFEEMKEAESKESSLVLGKS", "length": 1201, "header": "sp|A9JRI0-1|HEAT6_DANRE Isoform 1 of HEAT repeat-containing protein 6 OS=Danio rerio OX=7955 GN=heatr6 PE=2 SV=1 CANONICAL=A9JRI0-1" }, "isoforms": [ { "isoform_ac": "A9JRI0-1", "url": "https://www.uniprot.org/uniprotkb/A9JRI0/entry#A9JRI0-1", "sequence": { "sequence": "MAGKVTFLGSNSSFSPDGKTQGFKSASADTSRFVSLSKPQHELDGSAQAQISRCFNKLRSLSPSDSASLKTELNLLFDELISENYSSSNHDNIPPEVVCEILVQASRLVPLSQEHLIIKLCQMIHQLLNQLQIIVDEHTLDVLVSYCSRALRTCSSWTHSEVLLALSSLVYGNGSKCQRYLPDLLGPSGVLVKYGDPKQPDIELRRSAVHCIANLCLSVPSQPYLEEPYKSVCYGILLRTLQSTKPPDVDDIVFCTLLQSALKGMQYFLNGGKWKAVPNQDLGALLAVLKRFMFYGLPGISVEMPQVLYPAPLPQYETIPAVKPEPAQDTPAQKKTAASQQKKRKSRGKGKKGAGEGKQDGEADDVSAAGGGDQSGWSHGSQSSMLTSPSVATPQLYPSWKKCSSDSEFSDPEGGMQSKLRLYQARVRQSSLQCFLAVVKCVEKRILYGYWSSFVPDAPGIGGPPPLTLLTIALKDPLPKVRAGSLQVLSALLEGSRQFLSTAEDTGAPRQAFTPFSATLAASIRELHRGLLLALIAESSCQTLTQVLKCLAHLVSNVPYNRLRPGLLSPLWKQIRPYVRHRDVNVRVSSLTLFGALVSTQAPLPEVQLLLQQPGSASSLGSGISTPQESPLSWRQPARRDEEASSPAAAEGPEGPCWLLQLCVSLVTQPREEPYSDSDAGGSNGAPLEPSPVRLEALQVLAHLVKGYFSLAQASLLELGQLSARCLTEQDPSVQLHGAKLLEELGTGIIQQYRADANTPQSAKRVPVNQVVQFWSEVLGGPLISALQNEHHPTLQTSACDTLSSILPQAFSQLPDKTQVLCITILLGLTYSENSLVKAAAVRALGVYILFPCLREDVMFVADTANAILTALDDRSPNVRAKAAWSLGNLTDTLIVNMQSVGLEFQEDFSDMLLLNMLRSATKASADKDRVKSNAVRALGNLLHFLQPGHLGKPVFEQPLLEAMRALIDTVRGDATMKVRWNACYALGNAFRNQHLPLGSAVWSTEAFSALSCVVTSCKNFKVRIKSAAALSVPATRECYGDSQQFSEVWRSLAQALEHSEETEDFLEYRYCASLRSQLCRALLHLLSLCQPDDLPALGSSVSGQSRPALQALLISHLRDEGLVPSAGADGEEALDHSTPEDGWTLLTDTLTRLKGLLGEPVMDSNEDLESVLSFLQDVVRNFEEMKEAESKESSLVLGKS", "length": 1201, "header": "sp|A9JRI0-1|HEAT6_DANRE Isoform 1 of HEAT repeat-containing protein 6 OS=Danio rerio OX=7955 GN=heatr6 PE=2 SV=1 CANONICAL=A9JRI0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:567838", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567838", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A1EC95-1", "protein_name": "HEAT repeat-containing protein 6", "gene_name": "Heatr6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSALPGSKLSERVRTVGWQISRPYFCHFFPIRITAPPATCSANKGFPELEHARPCPKRCPGSISQAIHVGKMAAVQVAASLPCEQPREAPRELSLEQNNGFRRLSARLRALQPDDSTVSRMEIHLLFDQLISENYCEGGGVAPEDVSALLVRACQLVPLNQNHLVSKVSQLIHRLLNRLQVIVDEQNLDFLLTYTISAIQQCSPWTHMEILQALAALVYCNGSKCQKHLPDLLGKSGLLMKLSDVTHSDPEVRRAAVHCMANLCLSVPGQPYLEESYQLVCFQAFLTILQSPKSSDMDDITFCMLLQNALKGIQSLLNGGKMRLTQTEHLGALLAVLKKAMFHGLPGLNIEMPAVLYPTPLPQYDGRSPVKPQQPESSAARPSANKKKKYKVKPKKTQQGEKAEEEEPYGEVDAAPGLSMDQANTCVESAWCSSPWGSQGLPVDGGRATGREQVSSPFTISSWKRVSSSESDYSDAEGGMQGKMRSYQAKVRQGALACFLSTIKSIEKKVLYGYWSAFVPDTPELGSPQSVSLMTLTLKDPSPKTRACALQVLSAILEGSKQFLSVAEDTSDHKRAFTPFSVTIASSIRELHRCLLLALVAESSSQTLTQIIKCLANLVSNAPYNRLKLSLLTKVWNHIKPYIRHKDVNVRVSSLTLLGAVVSTHAPLPEVQLLLQQPCSSGRSSSSATPHLSTPDGWKALPAGPSLEEASLSSPKGTAEPCWLIRLCISTVVLPKEDSCSGSDAGSALGSTYEPSPMRLEALQVLAHLARGYFSMAQLYLMELGEVICKCMCEANPSIQLHGVKLLEELGTGLIQQYKPDSSTAPEQRVPVHMVAMFWTAMLNGPLPRALQSTEHPTLQASACDALSSILPEAFSSLPNDKQILCITMLLGLNDSKNHLVKAATSRALGVYVLFPCLRQDVIFVADTANAILMSLQDKSLNVRAKAAWSLGNLTDTLIVNMDTPDPSFQDEFSGLLLLKMLQSAIQASTDKDKVKSNAVRALGNLLHFLQPSHIERPRFAEIIEESIQALISTVVNEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYKALTSVVMSCKNFKVRIRSAAALSVPGRRAQYGSLEQFSQIWSALVTALQRSEDTTDFLEFKYCASLRTHVCQALLHLLGLASASDLPCIQETLTVNGDMIRSYILQFLKSGAGGDDPGAVHSPQERNQMVRVALRHIHSVQALAGDTAKGAIVGFLEDILTVHCDSSGERAVLRGSLDQ", "length": 1252 }, "evidence": [ { "id": "HGNC:24076", "url": "https://alliancegenome.org/gene/HGNC:24076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-118#orthology", "database": "AGR" }, { "id": "MGI:1919790", "url": "https://alliancegenome.org/gene/MGI:1919790#orthology", "database": "AGR" }, { "id": "RGD:1566204", "url": "https://alliancegenome.org/gene/RGD:1566204#orthology", "database": "AGR" }, { "id": "FB:FBgn0025621", "url": "https://alliancegenome.org/gene/FB:FBgn0025621#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6AI08-1", "protein_name": "HEAT repeat-containing protein 6", "gene_name": "HEATR6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVQVVGSWPSVQPREAPREAIPERGNGFRLLSARLCALRPDDSSSARTEIHLLFDQLISENYSEGSGVAPEDVSALLVQACRLVPLNQNHLVSKVSQLIHHLLNRLQVIVDEQHLDFLLAYTISAIHQCSSWTHREILQALAALVYCNGSKCQKYLPELLGNTGLLMKLSDLAQSDPEVRRAAVHCMANLCLSVPGQPYLEEPYQNVCFQAFLTILQSPKSSDMDDITFCMLLQNALKGIQSLLNGGRMKLTQTDELGALLAVLKKFMFHGLPGLNIEMPTVLYPTPLPQYDGRTPIKPQQSESSASRPTLNKKKKSKVKPKKIQQGEEEEKESSGEIEAAPVTGTGRVNLHEGNTWCPSSLGVQSLPLDGSGAAEKDGVSSSFSSSSWKRVSSSESDFSDAEGGMQSKMRSYQAKVRQGALVCFLSTIKSIEKKVLYGYWSAFIPDTPELGSPQSVSLMTLTLKDPSPKTRACALQVLSAILEGSKQFLSVAEDTSDHRRAFTPFSVMIACSIRELHRCLLLALVAESSSQTVTQIIKCLANLVSNAPYDRLKLSLLTKVWNQIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLGNSNSATPHLSPPDWWKKAPAGPSLEETSVSSPKGSSEPCWLIRLCISIVVLPKEDSCSGSDAGSAAGSTYEPSPMRLEALQVLTLLARGYFSMTQAYLMELGEVICKCMGEADPSIQLHGAKLLEELGTGLIQQYKPDSTAAPDQRAPVFLVVMFWTMMLNGPLPRALQNSEHPTLQASACDALSSILPEAFSNLPNDRQMLCITVLLGLNDSKNRLVKAATSRALGVYVLFPCLRQDVIFVADAANAILMSLEDKSLNVRAKAAWSLGNLTDTLIVNMETPDPSFQEEFSGLLLLKMLRSAIEASKDKDKVKSNAVRALGNLLHFLQPSHIEKPTFAEIIEESIQALISTVLTEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYNALTSVVTSCKNFKVRIRSAAALSVPGKREQYGSVDQYARIWNALVTALQKSEDTIDFLEFKYCVSLRTQICQALIHLLSLASASDLPCMKETLELSGNMVQSYILQFLKSGAEGDDTGAPHSPQERDQMVRMALKHMGSIQAPTGDTARRAIMGFLEEILAVCFDSSGSQGALPGLTNQ", "length": 1181 }, "evidence": [ { "id": "HGNC:24076", "url": "https://alliancegenome.org/gene/HGNC:24076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-118#orthology", "database": "AGR" }, { "id": "MGI:1919790", "url": "https://alliancegenome.org/gene/MGI:1919790#orthology", "database": "AGR" }, { "id": "RGD:1566204", "url": "https://alliancegenome.org/gene/RGD:1566204#orthology", "database": "AGR" }, { "id": "FB:FBgn0025621", "url": "https://alliancegenome.org/gene/FB:FBgn0025621#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6P1G0-1", "protein_name": "HEAT repeat-containing protein 6", "gene_name": "Heatr6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAVQVAASLPCGQPREAPRELSPEQDDGFRRLSARLRALQPDDSTVSRMEIHLLFDQLISENYSEGGGVAPEDVSALLVRACQLVPLNQNHLVSKVCQLIHRLLNRLQVVVDEPNLDFLLTYTISALQQCSSWTHMEILQALAALVYCNGSKCQKHLPDLLGKSGLLMKLSDLSHSDPEVRRAAVHCMANLCLSVPGQPYLEEPYQHVCFQAFLTILQSPKSSDMDDITFCMLLQNALKGIQSLLNGGKMRLTQTEHLGALLAVLKKAMFHGLPGLNIEMPAVLYPTPLPQYDGRSPVKPQQPESTTARSSANKKKKHKVKTKKTQQGEKAEEEEEEPCGEVEAAPGLSMDQANVSGESAWCSSPWGSQGLPVDGGRAAGREQASLPFASSSWKRVSSSESDYSDAEGGMQGKMRSYQAKVRQGALACFLSTIKSIEKKVLYGYWSAFVPDTPELGSPQSVSLMTLTLKDPSPKTRACALQVLSAILEGSKQFLSVAEDTSDHKRAFTPFSVTIASSIRELHRCLLLALVAESSSQTLTQIIKCLANLVSNAPYNRLKLSLLTKVWNHIKPYIRHKDVNVRVSSLTLLGAIVSTHAPLPEVQLLLQQPCSSGLSSSSSATPHLSTPDGWKTFPAGSSLEEASLSSPKGSSEPCWLIRLCISTVVLPKEDSCSGSDAGSALGSTYEPSPMRLEALQVLAHLARGYFSTAQLYLMELGEVICKCMCEANPSIQLHGVKLLEELGAGLIQQYKPDSNIAPEQRVPVHLVVVFWTAMLSGPLPRALQSAEHPTLQASACDALSSILPEAFSSLPNDKQILCITVLLGLNDSKNHLVKAATSRALGVYVLFPCLRQDVIFVADTANAILMSLQDKSLNVRAKAAWSLGNLTDTLIVNMDTPDPSFQDEFSGLLLLKMLQCAIQASTDKDKVKSNAVRALGNLLHFLQPSHVERPRFAEIIEESIQALISTVVNEAAMKVRWNACYAMGNVFKNPALPLGTAPWTSQAYKALTSVVMSCKNFKVRIRSAAALSVPSKRGQYGSLEQFIQIWSALVTALQKSEDTTDFLEFKYCASLRTHICQALLHLLSLASASDLPGIQETLKLHGDMIRSYILQFLKSGAEGDDPGAVHTPQERVQMVRVALKHIHRVQTLAGDTARGAIMGFLEDILTVHCDSSGEQVMLRGPSDQ", "length": 1184 }, "evidence": [ { "id": "HGNC:24076", "url": "https://alliancegenome.org/gene/HGNC:24076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-118#orthology", "database": "AGR" }, { "id": "MGI:1919790", "url": "https://alliancegenome.org/gene/MGI:1919790#orthology", "database": "AGR" }, { "id": "RGD:1566204", "url": "https://alliancegenome.org/gene/RGD:1566204#orthology", "database": "AGR" }, { "id": "FB:FBgn0025621", "url": "https://alliancegenome.org/gene/FB:FBgn0025621#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W5D3-1", "protein_name": "HEAT repeat-containing protein 6", "gene_name": "Dmel\\CG16989", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLRRELLEAESRTDQEEADRDSHLQLVREVDHNVGVPVGVAAYRLQQLIAGVRARGHHDLLRLWQLWLNELILAKKIILVRSHLLIEELLAGTELKPSVETVNLMLTVLKSTPKENLAGFWPRLSALTHAKDMDVALLLLQCQDRVLAELEESPEVAEHNQGLVNSLINMHFEGRWLVAKEQLPLLLAQSLQLIQKLVTRQPDYAAQRVPELMGLVQCYLQYGAEGETHLKPRKLPPAQQSAAYGQEKEEEDQLLAQMSRPCGRKNKVRKMRSLAKQRNQAVNEHHEPNPRERLVLMGNQDYGCLTGDSGENGLPSDSDQQQTENKHHRHQEAKVRISALHLLSTLTNQLPRRSFYGYWHVLFPDGDAGGTPHLLLLGLKDTNFRCRALALQVGAQLLYGSKAFLSQACSLGPSNFTPFAVSLASSVLTAYRILIAILEREYTPPVLTQCLKCLAVLVQATPFHQLEMGFVYEFVGHVKKLIKSSDPPVAVSALLVMEMLVGTSKLTPEIASSIGLAPSQRNLQMEHASTAETYQELCDSDAEMELEEGDEQQQPSQNNVVNPVHTVSPTIPRNSWLLRQVLRCLEGMRIPSAVRLECFQVLQAMATHIGLLRGHQVRLSRVISAGLTDPATDVKLYAARCLDSVGYQLGRLLPEPAERELQMSFWLTLLPATYEAYDSAGFSLKCALCDALSNMGAISFERLPDGQRTALLAFLSGCASDDHEETLVRVAALRAMAVYVLHPSLRTDLGFVENAAELTLRILGDSQLLARIKAAWALGNISDALVAGIPNQTERISAELLERLIQAATKSCADNDKVRANAVRALGNLLQILQVQPLGNGELMQVAMSKLLDCVTLPGNAKVKWNACYVIGNLVKHRAFFANNRLAGILFPTLCQLVVQHANFKVRTNAAGVLLQVKQREDFSAHFPLLWRSLLDALVRSNVLESFEEYNHRDALQQQLCLAIAHLLLLARSSDLPMMRESLEEDRLEEVQATWRRVAFRIVPEQSDPLFTCSPLLQQRLQGDVNNLQRCALAFITSTLRLDP", "length": 1045 }, "evidence": [ { "id": "HGNC:24076", "url": "https://alliancegenome.org/gene/HGNC:24076#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080204-118", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080204-118#orthology", "database": "AGR" }, { "id": "MGI:1919790", "url": "https://alliancegenome.org/gene/MGI:1919790#orthology", "database": "AGR" }, { "id": "RGD:1566204", "url": "https://alliancegenome.org/gene/RGD:1566204#orthology", "database": "AGR" }, { "id": "FB:FBgn0025621", "url": "https://alliancegenome.org/gene/FB:FBgn0025621#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 173, "end_pos": 175, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" }, { "start_pos": 889, "end_pos": 891, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 173, "end_pos": 175 }, { "start_pos": 84, "end_pos": 86 }, { "start_pos": 889, "end_pos": 891 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0JZP3-1", "uniprot_ac": "B0JZP3", "uniprot_id": "THEM6_DANRE", "mass": { "chemical_mass": 23358.0, "monoisotopic_mass": 23358.0 }, "refseq": { "ac": "NP_001116101", "name": "protein THEM6 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116101" }, "gene_names": [ { "name": "them6", "type": "recommended", "evidence": [ { "id": "B0JZP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0JZP3" } ] }, { "name": "si:ch73-52e5.2", "type": "synonym", "evidence": [ { "id": "NP_001116101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116101" }, { "id": "B0JZP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0JZP3" } ] }, { "name": "them6", "type": "synonym", "evidence": [ { "id": "NP_001116101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116101" } ] } ], "protein_names": [ { "name": "Protein THEM6", "type": "recommended", "evidence": [ { "id": "B0JZP3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0JZP3/entry#names_and_taxonomy" } ] }, { "name": "UPF0670 protein C8orf55 homolog", "type": "synonym", "evidence": [ { "id": "NP_001116101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116101" } ] }, { "name": "UPF0670 protein THEM6 homolog", "type": "synonym", "evidence": [ { "id": "NP_001116101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116101" } ] }, { "name": "protein THEM6 precursor", "type": "synonym", "evidence": [ { "id": "NP_001116101", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116101" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC159266.1, GO943298.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC159266.1. On Jul 31, 2008 this sequence version replaced XP_001923686.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001116101", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116101" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0JZP3", "url": "https://www.uniprot.org/uniprotkb/B0JZP3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "them6", "url": "https://www.uniprot.org/uniprotkb/B0JZP3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-341", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-341", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "B0JZP3", "url": "https://alphafold.ebi.ac.uk/entry/B0JZP3", "database": "AlphaFoldDB", "categories": [] }, { "id": "cd00586", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00586", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100142654", "url": "https://www.ncbi.nlm.nih.gov/gene/100142654", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029069", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029069", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051490", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051490", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100142654", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100142654", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "B0JZP3", "url": "https://www.orthodb.org/?gene=B0JZP3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12475", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12475", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12475:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12475:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13279", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13279", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:B0JZP3", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:B0JZP3", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001116101", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116101", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0JZP3", "url": "https://www.uniprot.org/uniprotkb/B0JZP3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0JZP3-1", "url": "https://www.uniprot.org/uniprotkb/B0JZP3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-341", "url": "https://zfin.org/ZDB-GENE-070912-341", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLLWFLSGSLLLFGTFDVWYFLRGLWVALRCCFQSPIRDVLAEQVVHGRVLLHDMDFMCHMNNARYLRECDFARFAHGTRIGLFMAARALKATMVVGATTIRYRRSLALGEGFELRTRIVSWDEKSFYLEQRFVSKSDGFISAVMLCRQNVIRGSPQNILEFLCKRKVDCPDISEDLQHWIRFISASSQALRAESGLDDKTK", "length": 202, "header": "sp|B0JZP3-1|THEM6_DANRE Isoform 1 of Protein THEM6 OS=Danio rerio OX=7955 GN=them6 PE=2 SV=1 CANONICAL=B0JZP3-1" }, "isoforms": [ { "isoform_ac": "B0JZP3-1", "url": "https://www.uniprot.org/uniprotkb/B0JZP3/entry#B0JZP3-1", "sequence": { "sequence": "MLLWFLSGSLLLFGTFDVWYFLRGLWVALRCCFQSPIRDVLAEQVVHGRVLLHDMDFMCHMNNARYLRECDFARFAHGTRIGLFMAARALKATMVVGATTIRYRRSLALGEGFELRTRIVSWDEKSFYLEQRFVSKSDGFISAVMLCRQNVIRGSPQNILEFLCKRKVDCPDISEDLQHWIRFISASSQALRAESGLDDKTK", "length": 202, "header": "sp|B0JZP3-1|THEM6_DANRE Isoform 1 of Protein THEM6 OS=Danio rerio OX=7955 GN=them6 PE=2 SV=1 CANONICAL=B0JZP3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100142654", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100142654", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P38256-1", "protein_name": "Probable thioesterase YBR096W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGVCTIFRWLFAAYLLSSYKSLPGAYFVRFYYYVIQNLFLPMFTGFETENIKKLEKNEYGCFSYTSLDTYASPFECDFYFHKSNSTYFAELDISRGNLMCKIFQKLMLNSKHYPYIPVANVFTNFLKEIKPFQKYSVSSRIICWDEKWIYVMSRFTIKKGTVLCSLSLTKYVLKDGRKTIKPKDALEYCGLYNEKVAKISEDNLKLLTERCGFHETVPLENLSQEYCSEI", "length": 230 }, "evidence": [ { "id": "MGI:1925301", "url": "https://alliancegenome.org/gene/MGI:1925301#orthology", "database": "AGR" }, { "id": "RGD:1359378", "url": "https://alliancegenome.org/gene/RGD:1359378#orthology", "database": "AGR" }, { "id": "FB:FBgn0029838", "url": "https://alliancegenome.org/gene/FB:FBgn0029838#orthology", "database": "AGR" }, { "id": "FB:FBgn0029839", "url": "https://alliancegenome.org/gene/FB:FBgn0029839#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-341", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-341#orthology", "database": "AGR" }, { "id": "HGNC:29656", "url": "https://alliancegenome.org/gene/HGNC:29656#orthology", "database": "AGR" }, { "id": "SGD:S000000300", "url": "https://alliancegenome.org/gene/SGD:S000000300#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5XIE1-1", "protein_name": "Protein THEM6", "gene_name": "Them6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMELLVVSLSLALAFFALLDGWYLVRVPCAVLRARLLQPRVRDLLAEQLYAGRVLPSDLDLLLHMNNARYLREADVARAAHLTRCGVLGALRDLGAHTVLAASCARYRRSLRLFEPFEVHTRLLGWDDRAFYLEARFVSLRDGFVCALLRFRQHVLGTSPDRVVQHLCKRRVEPPELPEDLKHWITYNETSSQLLRAESGLSDRKDQ", "length": 207 }, "evidence": [ { "id": "MGI:1925301", "url": "https://alliancegenome.org/gene/MGI:1925301#orthology", "database": "AGR" }, { "id": "RGD:1359378", "url": "https://alliancegenome.org/gene/RGD:1359378#orthology", "database": "AGR" }, { "id": "FB:FBgn0029838", "url": "https://alliancegenome.org/gene/FB:FBgn0029838#orthology", "database": "AGR" }, { "id": "FB:FBgn0029839", "url": "https://alliancegenome.org/gene/FB:FBgn0029839#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-341", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-341#orthology", "database": "AGR" }, { "id": "HGNC:29656", "url": "https://alliancegenome.org/gene/HGNC:29656#orthology", "database": "AGR" }, { "id": "SGD:S000000300", "url": "https://alliancegenome.org/gene/SGD:S000000300#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80ZW2-1", "protein_name": "Protein THEM6", "gene_name": "Them6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLELLVASLSLALAFFALLDGWYLVRVPCAVLRARLLQPRVRDLLAEQRYAGRVLPSDLDLLLHMNNARYLREADVARAAHLTRCGVLGALRDLNAHTVLAASCARYRRSLRLFEPFEVHTRLQGWDDRAFYLEARFVSLRDGFVCALLRFRQHVLGTSPDRVVQHLCKRRVEPPELPEDLKHWISYNETSSQLLRAESGLSDRKDQ", "length": 207 }, "evidence": [ { "id": "MGI:1925301", "url": "https://alliancegenome.org/gene/MGI:1925301#orthology", "database": "AGR" }, { "id": "RGD:1359378", "url": "https://alliancegenome.org/gene/RGD:1359378#orthology", "database": "AGR" }, { "id": "FB:FBgn0029838", "url": "https://alliancegenome.org/gene/FB:FBgn0029838#orthology", "database": "AGR" }, { "id": "FB:FBgn0029839", "url": "https://alliancegenome.org/gene/FB:FBgn0029839#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-341", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-341#orthology", "database": "AGR" }, { "id": "HGNC:29656", "url": "https://alliancegenome.org/gene/HGNC:29656#orthology", "database": "AGR" }, { "id": "SGD:S000000300", "url": "https://alliancegenome.org/gene/SGD:S000000300#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WUY1-1", "protein_name": "Protein THEM6", "gene_name": "THEM6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGLLVALLALGLAVFALLDVWYLVRLPCAVLRARLLQPRVRDLLAEQRFPGRVLPSDLDLLLHMNNARYLREADFARVAHLTRCGVLGALRELRAHTVLAASCARHRRSLRLLEPFEVRTRLLGWDDRAFYLEARFVSLRDGFVCALLRFRQHLLGTSPERVVQHLCQRRVEPPELPADLQHWISYNEASSQLLRMESGLSDVTKDQ", "length": 208 }, "evidence": [ { "id": "MGI:1925301", "url": "https://alliancegenome.org/gene/MGI:1925301#orthology", "database": "AGR" }, { "id": "RGD:1359378", "url": "https://alliancegenome.org/gene/RGD:1359378#orthology", "database": "AGR" }, { "id": "FB:FBgn0029838", "url": "https://alliancegenome.org/gene/FB:FBgn0029838#orthology", "database": "AGR" }, { "id": "FB:FBgn0029839", "url": "https://alliancegenome.org/gene/FB:FBgn0029839#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-341", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-341#orthology", "database": "AGR" }, { "id": "HGNC:29656", "url": "https://alliancegenome.org/gene/HGNC:29656#orthology", "database": "AGR" }, { "id": "SGD:S000000300", "url": "https://alliancegenome.org/gene/SGD:S000000300#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W439-1", "protein_name": "Protein THEM6", "gene_name": "BcDNA:RH58440", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEQLCYLALSVLLAIIVVYGLLELHYFLRMCLCVLLARFVKRRCHILDTTTVNGLCLTNDVDTLLYHMNNARYFRELDFARVDFYERTNLYRTITGMGGSVFQGAATIRYRRFIRPFHRFNIISRIIYWDEQSLFMEHRFVRPSDKFVHCIAICRQRVIDVSMEAVMSELLPRTSSNGFRATVLTSLAAPSPAAGGISNPAMDTSLAENGHGTTSGGAAGTGATASATAAHCLKLKPSLPPELAKWIEYNDMSSKNLRSGC", "length": 261 }, "evidence": [ { "id": "MGI:1925301", "url": "https://alliancegenome.org/gene/MGI:1925301#orthology", "database": "AGR" }, { "id": "RGD:1359378", "url": "https://alliancegenome.org/gene/RGD:1359378#orthology", "database": "AGR" }, { "id": "FB:FBgn0029839", "url": "https://alliancegenome.org/gene/FB:FBgn0029839#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-341", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-341#orthology", "database": "AGR" }, { "id": "HGNC:29656", "url": "https://alliancegenome.org/gene/HGNC:29656#orthology", "database": "AGR" }, { "id": "SGD:S000000300", "url": "https://alliancegenome.org/gene/SGD:S000000300#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W440-1", "protein_name": "Protein THEM6", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSWLVVLLILYVIWDVNYFIRCVFTVFAGRLFQRKRKVTDTTTIYGLCTSQDVDIFIRHMNNARYLRELDFARFHFYALTGLYERIRDRRGGAVQGASSVRYRRTIPIFHPYKIQTKLIWWDDKAIYLEQQFITLSDGFVRAVAMSKQNITNCNVLEVLKTYPETAQRPEKPEELKLWLDAIELSSQKLRKDK", "length": 193 }, "evidence": [ { "id": "MGI:1925301", "url": "https://alliancegenome.org/gene/MGI:1925301#orthology", "database": "AGR" }, { "id": "RGD:1359378", "url": "https://alliancegenome.org/gene/RGD:1359378#orthology", "database": "AGR" }, { "id": "FB:FBgn0029838", "url": "https://alliancegenome.org/gene/FB:FBgn0029838#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-341", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-341#orthology", "database": "AGR" }, { "id": "HGNC:29656", "url": "https://alliancegenome.org/gene/HGNC:29656#orthology", "database": "AGR" }, { "id": "SGD:S000000300", "url": "https://alliancegenome.org/gene/SGD:S000000300#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "B0JZP3", "url": "https://www.uniprot.org/uniprotkb/B0JZP3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0R089-1", "uniprot_ac": "B0R089", "uniprot_id": "B0R089_DANRE", "mass": { "chemical_mass": 49478.0, "monoisotopic_mass": 49478.0 }, "refseq": { "ac": "NP_001007342", "name": "rho guanine nucleotide exchange factor 39 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007342" }, "gene_names": [ { "name": "arhgef39", "type": "recommended", "evidence": [ { "id": "B0R089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R089" } ] }, { "name": "arhgef39", "type": "synonym", "evidence": [ { "id": "NP_001007342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007342" } ] }, { "name": "zgc:103517", "type": "synonym", "evidence": [ { "id": "NP_001007342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007342" }, { "id": "B0R089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R089" } ] } ], "protein_names": [ { "name": "Rho guanine nucleotide exchange factor 39 isoform 1", "type": "synonym", "evidence": [ { "id": "B0R089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R089/entry#names_and_taxonomy" } ] }, { "name": "Rho guanine nucleotide exchange factor 39 isoform X1", "type": "synonym", "evidence": [ { "id": "B0R089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R089/entry#names_and_taxonomy" } ] }, { "name": "rho guanine nucleotide exchange factor 39 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001007342", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007342" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC085538.1, SRR26395014.37245.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Jun 18, 2016 this sequence version replaced NP_001007342.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001007342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007342" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R089", "url": "https://www.uniprot.org/uniprotkb/B0R089" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "arhgef39", "url": "https://www.uniprot.org/uniprotkb/B0R089", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041114-28", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-28", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000013476", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000013476", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "492469", "url": "https://www.ncbi.nlm.nih.gov/gene/492469", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042987", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042987", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:492469", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492469", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LLMCTDQ", "url": "https://omabrowser.org/oma/group/LLMCTDQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0R089", "url": "https://www.orthodb.org/?gene=B0R089", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1QG07", "url": "https://www.orthodb.org/?gene=F1QG07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47056", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47056", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47056:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47056:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-193648", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-193648", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-416482", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-416482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001007342", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007342", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0R089", "url": "https://www.uniprot.org/uniprotkb/B0R089", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0R089-1", "url": "https://www.uniprot.org/uniprotkb/B0R089-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QG07", "url": "https://www.uniprot.org/uniprotkb/F1QG07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QG07-1", "url": "https://www.uniprot.org/uniprotkb/F1QG07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041114-28", "url": "https://zfin.org/ZDB-GENE-041114-28", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSFSPSPLSPMSGRSIQEQRERWERKRSRTAREMIQSEQRYCQQLELVVTYFVEILKAKGTLRQDIRESIFSSIKSIHLINQTLLAHLEMGRFGIGFEEFCTHLQLYNTYIDNIQTAKKVLMVQVKKSKAFRRFKKLQESRPEFSQQKLEDLLELPLQRIQQYKHFLRDLTENTGPDNPEFQQLSKAVKAISEVAQRIQDNARSHENHLQLRRVQKQLKGRKTRILTPGRWYIREGWLKTVPPKGTEAKPKMFYLFSDILLQAKPCSPMHPTNGDKFTCQRVYPLKECTVDKVFGHTKSQGGLISLTFARAKLLLMSDDQVDINDWYRSLCLTIGQLKSRNTVVHRRDELCRTPIRSDADDQSSTESQNTRGTKRAMMLDDEVREESSRSLSSTEESSRSATKRRKPDQTPADGRSQESSGSSCVIL", "length": 427, "header": "tr|B0R089-1|B0R089_DANRE Isoform 1 of Rho guanine nucleotide exchange factor 39 isoform X1 OS=Danio rerio OX=7955 GN=arhgef39 PE=4 SV=1 CANONICAL=B0R089-1" }, "isoforms": [ { "isoform_ac": "B0R089-1", "url": "https://www.uniprot.org/uniprotkb/B0R089/entry#B0R089-1", "sequence": { "sequence": "MSFSPSPLSPMSGRSIQEQRERWERKRSRTAREMIQSEQRYCQQLELVVTYFVEILKAKGTLRQDIRESIFSSIKSIHLINQTLLAHLEMGRFGIGFEEFCTHLQLYNTYIDNIQTAKKVLMVQVKKSKAFRRFKKLQESRPEFSQQKLEDLLELPLQRIQQYKHFLRDLTENTGPDNPEFQQLSKAVKAISEVAQRIQDNARSHENHLQLRRVQKQLKGRKTRILTPGRWYIREGWLKTVPPKGTEAKPKMFYLFSDILLQAKPCSPMHPTNGDKFTCQRVYPLKECTVDKVFGHTKSQGGLISLTFARAKLLLMSDDQVDINDWYRSLCLTIGQLKSRNTVVHRRDELCRTPIRSDADDQSSTESQNTRGTKRAMMLDDEVREESSRSLSSTEESSRSATKRRKPDQTPADGRSQESSGSSCVIL", "length": 427, "header": "tr|B0R089-1|B0R089_DANRE Isoform 1 of Rho guanine nucleotide exchange factor 39 isoform X1 OS=Danio rerio OX=7955 GN=arhgef39 PE=4 SV=1 CANONICAL=B0R089-1" }, "locus": {} }, { "isoform_ac": "F1QG07-1", "url": "https://www.uniprot.org/uniprotkb/B0R089/entry#F1QG07-1", "sequence": { "sequence": "MSFSPSPLSPMSGRSIQEQRERWERKRSRTAREMIQSEQRYCQQLELVVTYFVEILKAKGTLRQDIRESIFSSIKSIHLINQTLLAHLEMGRFGIGFEEFCTHLQLYNTYIDNIQTAKKVLMVQVKKSKAFRRFKKLQESRPEFSQQKLEDLLELPLQRIQQYKHFLRDLTENTGPDNPEFQQLSKAVKAISEVAQRIQDNARSHENHLQLRRVQKQLKGRKTRILTPGRWYIREGWLKTVPPKGTEAKPKMFYLFSDILLQAKPCSPMHPTNGDKFTCQRVYPLKECTVDKVFGHTKSQGGLISLTFARAKLLLMSDDQVDINDWYRSLCLTIGQLKSRNTVVHRRDELCRTPIRSDADDQSSTESQNTRGTKRAMMLDDEVREESSRSLSSTEESSRSATKRRKPDQTPADGSQESSGSSCVIL", "length": 426, "header": "tr|F1QG07-1|F1QG07_DANRE Computationally mapped isoform of Rho guanine nucleotide exchange factor 39 isoform 2 OS=Danio rerio OX=7955 GN=arhgef39 PE=4 SV=1 CANONICAL=B0R089-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B0R089", "url": "https://www.uniprot.org/uniprotkb/B0R089" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:492469", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:492469", "resource": "KEGG Pathway" }, { "id": "R-DRE-193648", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-193648", "resource": "Reactome", "description": "NRAGE signals death through JNK" }, { "id": "R-DRE-416482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-416482", "resource": "Reactome", "description": "G alpha (12/13) signalling events" }, { "id": "R-DRE-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "B0BN40-1", "protein_name": "Rho guanine nucleotide exchange factor 39", "gene_name": "Arhgef39", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MESLGSSECCPVRQQRARWERKRVCTARELLETERRYQEQLGLVATYFLGILKAKGTLRPPERQTLFGTWELIYAASLELLPYLEEGQWGPGLQGFCPHLELYTQFAANAERSQTTLQEQLKKNKRFRRFVRLQEGRPEFRGLQLQDLLPLPLQRLQQYENLVVALAENTVPNSSDYQQLTRAARLVSETAQKVHAIGQNRKNEQHLLRVQALLSGRKAKGLTSGRWFLRQGWLLVVPPTGEPRPRMFFLFSDALLMAKPRPPLHLLKSGTFVCRALYPMTQCQLSRVFGHSGGPCGGLLSLSFPHEKLLLMSTDQEELSQWYHSLTQAIRSQKNSAHRSVPAT", "length": 344 }, "evidence": [ { "id": "HGNC:25909", "url": "https://alliancegenome.org/gene/HGNC:25909#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-28", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-28#orthology", "database": "AGR" }, { "id": "MGI:3036286", "url": "https://alliancegenome.org/gene/MGI:3036286#orthology", "database": "AGR" }, { "id": "RGD:1310376", "url": "https://alliancegenome.org/gene/RGD:1310376#orthology", "database": "AGR" }, { "id": "FB:FBgn0035761", "url": "https://alliancegenome.org/gene/FB:FBgn0035761#orthology", "database": "AGR" }, { "id": "B0R089", "url": "https://omabrowser.org/oma/group/B0R089/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1NHV7-1", "protein_name": "Rho guanine nucleotide exchange factor 39", "gene_name": "ARHGEF39", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSYSPPAPMAGANTVEEQRARWERKRSRTAKELLETEHRYLEQLDLVVTFFVTILKAKGTLKPAVMETIFGPLESIYSASQVLSLHLERGNLGLGLENFCQKLELYGHYAENFEQANKTLMEQLRKNKSFRRFKKLQETRPQFQGRKLEDLLPLPLQRLHQYKHFLRDLLENTSPASAEYQKLAKAVKSVSEVSQWVQDIACKRENSLQLHRVQKLLKGQKTRVLTPGRWYIREGWLLVVPSKGDELKRRMFFLFSDILISTKPCHPLHLLNSTKFACTAVYPLHQCVVDKVFGHTQSEGGLLSLSFPHKTLLLMSTDQQDINDWYQSLTTAVRQLKA", "length": 338 }, "evidence": [ { "id": "B0R089", "url": "https://omabrowser.org/oma/group/B0R089/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1SG02-1", "protein_name": "Rho guanine nucleotide exchange factor 39", "gene_name": "ARHGEF39", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEIPGPSARCPVQEQRARWERKRACTARELLETERRYQEQLGLVATYFVGILRAKGTLRPPERQALFGPWELIYRASQELLLHLEGGRWGQGLEDFCPHLELYTQFAANAERSWTTLQEQLKKNRRFRRFVRLQEGRPEFGGLQLQDLLPLPLQRLQQYENLAVALAENTGPNSPDQEQLARAARLISETAQRVHTIGQKQKNDQHLQRVQALLSGRQAKGLTSGRWFLRQGWLLVVPPQGKPRPRMFFLFSDALLMAKPRPPLHLLQSGTFACRALYPMAECQLQRVFGHSGGSCGGLLSLTFPHEKLLLMSTDQEELLLWYHSLTLAISSQKN", "length": 335 }, "evidence": [ { "id": "B0R089", "url": "https://omabrowser.org/oma/group/B0R089/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "O88387-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 4", "gene_name": "Fgd4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEESNPAPTSCASKGKHSKVSDLISHFEGGSVLSSYTDVQKDSTMNLNIPQTPRQHGLTSTTPQKLPSHKSPQKQEKDSDQNQGQHGCLANGVAAAQSQMECETEKEAALSPETDTQTAAASPDAHVLNGVRNETTTDSASSVTNSHDENACDSSCRTQGTDLGLPSKEGEPVIEAELQERENGLSTEGLNPLDQHHEVKETNEQKLHKIATELLLTERAYVSRLNLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAVELVKNMTERVPQFKSVTEEIQKQKICGSLTLQHHMLEPIQRIPRYEMLLKDYLKKLSPDAPDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPRFSLVGSKFTVRTRVGIDGMKIVETHNEEYPHTFQVSGKERTLELQASSEQDKEEWIKALQESIDAFHQRHETFRNAIAKENDIPLEVSTAELGKRAPRWIRDNEVTMCMKCKESFNALTRRRHHCRACGHVVCWKCSDYKAQLEYDGGRLNKVCKDCYQIMSGFAESEEKKRRGILEIESAEVSGNSEVCSFLQYMEKSKPWQKIWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGYIVDDMPKSADLPHSFKLTQSKSVHSFAADSEELKQKWLKIILLAVTGETPDGPSEHLDTLDNLPGPKEKSEC", "length": 766 }, "evidence": [ { "id": "FB:FBgn0035761", "url": "https://alliancegenome.org/gene/FB:FBgn0035761#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O88842-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 3", "gene_name": "Fgd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MELGRSSSTPQEEAISPLGVLGTGPSSSPLGKLQALPIGPGAHRGAHSSSAPAGDSSTREPSGAMKIPNRDSGIDSPSSSVASENFPCEESSEGSPSPAILGLPSETASDSRVPQDNPQEEEDSGVGEEPDPKVTLFRPQEDVSLTQCSDPQKLLHIAQELLHTEEAYVKRLHLLDQVFCTKLTEAGIPLEVTTGIFSNISSIYRFHGQFLLPELQKRITEEWDTNPRLGDILQKLAPFLKMYGEYVKNFDRAMGLVSTWTQRSPQFKDVIHTIQKQEVCGNLTLQHHMLEPVQRVPRYELLLKDYLKRLPRDAPDRKDAERSLELISTAADHSNAAIRKMEKMHKLLEVYEQLGGEEDIVNPANELIKEGSIQKLSAKNGTTQDRHLFLFNNVMLYCVPKLRLMGQKLSVREKMDISDLQVQDIVKPNAACTFIITGRKRSLELQTRTEEEKKEWIQVIQATVEKHKQKSETFRAFGGACSQDEEPTLSPDQPVMSTSSVEPAGVADSNGGTPGIESRKSSSKTRRDKEKPGCKSCGETFNSITKRRYRCKLCGEVICRKCSEFKAENSKQSRVCRECFLEEPLVPPSPSSETPTELKQNAEKPPSVDPRPSLLCGTLNLSDDGTTWNEVWAAIPESDPQVLDLLAGSQAGRLLYSIPLSGCNITMPDPEEGLEAGCAWKLHQGSQTWWLSAPSTKLQQCWLKALGTAVHGDTAGDRPGASQPQAPAGTDTP", "length": 733 }, "evidence": [ { "id": "FB:FBgn0035761", "url": "https://alliancegenome.org/gene/FB:FBgn0035761#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q0P5E3-1", "protein_name": "Rho guanine nucleotide exchange factor 39", "gene_name": "ARHGEF39", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MESPAPGARCPVQEQRARWERKRACTARELLETERRYQEQLGLVATYFVAILRAKGTLRPPERQALFGPWELIYGASQELLPYLEGGRWGQGLEGFCNHLELYTQFAANVERSRTILQEQLKKNKHFRRFVRLQEGRPEFGGLQLQDLLPLPLQRLQQYENLAVALAENTGPNSPEHKQLTRAAQLISETAQRVHTIGQKQKNEQHLQRIQALLSGRQAKGLISGRWFLRQGWLLVVPPRGEPRPRMFFLFSDALLMAKPRPPLHLLQSGTFACRALYPMGECQLHRVFGHSGGPCGGLLSLSFPHEKLLLMSTDQEELSHWYHSLTLAISSQKN", "length": 335 }, "evidence": [ { "id": "B0R089", "url": "https://omabrowser.org/oma/group/B0R089/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q66JY6-1", "protein_name": "Rho guanine nucleotide exchange factor 39", "gene_name": "Arhgef39", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MESSGSAACCPVLQQRARWERKRVCTARELLETERRYQEQLGLVATYFLRILKAKGTLRPPELQTLFGTWELIYAASLELLPYLEEGQWGLGLQGFCPHLELYAQFAANAERSQTTLQAQLKKNKRFRRFVKLQEGRPEFRGLQLQDLLPLPLQRLQQYENLVVALAENTVPNSPDYQQLTRAARLVSETAQKVHAIGQSQKNDQHLLRVQALLSGRKAKGLTSGRWFLRQGWLLVVPPTGEPRPRMFFLFSDVLLMAKPRPPLHLLKSGTFVCRALYPMSQCHLSRVFGHSGGPCGGLLSLSFPHEKLLLMSTDQEELSQWHHSLTLAIRSQKSSTHRSVTAT", "length": 344 }, "evidence": [ { "id": "HGNC:25909", "url": "https://alliancegenome.org/gene/HGNC:25909#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-28", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-28#orthology", "database": "AGR" }, { "id": "MGI:3036286", "url": "https://alliancegenome.org/gene/MGI:3036286#orthology", "database": "AGR" }, { "id": "RGD:1310376", "url": "https://alliancegenome.org/gene/RGD:1310376#orthology", "database": "AGR" }, { "id": "FB:FBgn0035761", "url": "https://alliancegenome.org/gene/FB:FBgn0035761#orthology", "database": "AGR" }, { "id": "B0R089", "url": "https://omabrowser.org/oma/group/B0R089/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N4T4-1", "protein_name": "Rho guanine nucleotide exchange factor 39", "gene_name": "ARHGEF39", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELSCPGSRCPVQEQRARWERKRACTARELLETERRYQEQLGLVATYFLGILKAKGTLRPPERQALFGSWELIYGASQELLPYLEGGCWGQGLEGFCRHLELYNQFAANSERSQTTLQEQLKKNKGFRRFVRLQEGRPEFGGLQLQDLLPLPLQRLQQYENLVVALAENTGPNSPDHQQLTRAARLISETAQRVHTIGQKQKNDQHLRRVQALLSGRQAKGLTSGRWFLRQGWLLVVPPHGEPRPRMFFLFTDVLLMAKPRPPLHLLRSGTFACKALYPMAQCHLSRVFGHSGGPCGGLLSLSFPHEKLLLMSTDQEELSRWYHSLTWAISSQKN", "length": 335 }, "evidence": [ { "id": "HGNC:25909", "url": "https://alliancegenome.org/gene/HGNC:25909#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-28", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-28#orthology", "database": "AGR" }, { "id": "MGI:3036286", "url": "https://alliancegenome.org/gene/MGI:3036286#orthology", "database": "AGR" }, { "id": "RGD:1310376", "url": "https://alliancegenome.org/gene/RGD:1310376#orthology", "database": "AGR" }, { "id": "FB:FBgn0035761", "url": "https://alliancegenome.org/gene/FB:FBgn0035761#orthology", "database": "AGR" }, { "id": "B0R089", "url": "https://omabrowser.org/oma/group/B0R089/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96M96-1", "protein_name": "FYVE, RhoGEF and PH domain-containing protein 4", "gene_name": "FGD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEIKPASASCVSKEKPSKVSDLISRFEGGSSLSNYSDLKKESAVNLNAPRTPGRHGLTTTPQQKLLSQHLPQRQGNDTDKTQGAQTCVANGVMAAQNQMECEEEKAATLSSDTSIQASEPLLDTHIVNGERDETATAPASPTTDSCDGNASDSSYRTPGIGPVLPLEERGAETETKVQERENGESPLELEQLDQHHEMKETNEQKLHKIANELLLTERAYVNRLDLLDQVFYCKLLEEANRGSFPAEMVNKIFSNISSINAFHSKFLLPELEKRMQEWETTPRIGDILQKLAPFLKMYGEYVKGFDNAMELVKNMTERIPQFKSVVEEIQKQKICGSLTLQHHMLEPVQRIPRYEMLLKDYLRKLPPDSLDWNDAKKSLEIISTAASHSNSAIRKMENLKKLLEIYEMLGEEEDIVNPSNELIKEGQILKLAARNTSAQERYLFLFNNMLLYCVPKFSLVGSKFTVRTRVGIDGMKIVETQNEEYPHTFQVSGKERTLELQASSAQDKEEWIKALQETIDAFHQRHETFRNAIAKDNDIHSEVSTAELGKRAPRWIRDNEVTMCMKCKEPFNALTRRRHHCRACGYVVCWKCSDYKAQLEYDGGKLSKVCKDCYQIISGFTDSEEKKRKGILEIESAEVSGNSVVCSFLQYMEKSKPWQKAWCVIPKQDPLVLYMYGAPQDVRAQATIPLLGYVVDEMPRSADLPHSFKLTQSKSVHSFAADSEELKQKWLKVILLAVTGETPGGPNEHPATLDDHPEPKKKSEC", "length": 766 }, "evidence": [ { "id": "FB:FBgn0035761", "url": "https://alliancegenome.org/gene/FB:FBgn0035761#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VS45-1", "protein_name": "Rho guanine nucleotide exchange factor 4, isoform A", "gene_name": "RhoGEF4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFTPRQKGYGNGFIHSPQTPLSFSRELRQVLQERNLLTAKSRRKVCSMLDSNNSSPIGSPNPDAGKRLGFRRQAIQEIISSEKSYLEQLELLMNFFVRPLKEQAIIDCSNHTLLFGQIEMIHNLNGEFLRELEANMENVAHAFLKMAPFFKLYSVYAFDYRGALFIIQDLISKNPVFRKFLEQTESRPEVQRKLNSLMIVPIQRVPRYKLLLEQVLLYTSPADADYKLLKESVKEIEATASHINTCVEEQEITQYLIHLQNSLVNRTPNIVKPSRRVIKEGVLQKITHKGTEIKRYCVLMSDIFMYCKMIKERAPNTVVENSLECCCIFPLKKCKVYEMLPGNFKLTCQSDGIIFGSGDVQLSRTWVGFIRDAIDLHVQCRKTLRKDSSKRTPIRKKDMKKFGADYVLSPNKRKCEYDTVFRNKNRSTDSEEETEDSACFSRKRKVASGILRAPNGNPMGKASSSSSSSVSMKRVAPPPPAPPPPPAVQMRHQPGRPGELATASKENRISKLYKKIAAGDKVANVRGILKRSNVPAPNNDHDPSYGFASRYSDSKSYFRAHNVDNTIPTFVKREDLFNGDNMFPVHLKSHEEICTPPQKKRVKFDDTLDAVSPVLVEKPFAFSSESSSALKPTSLRERIYDFFANLF", "length": 647 }, "evidence": [ { "id": "HGNC:25909", "url": "https://alliancegenome.org/gene/HGNC:25909#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041114-28", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041114-28#orthology", "database": "AGR" }, { "id": "MGI:3036286", "url": "https://alliancegenome.org/gene/MGI:3036286#orthology", "database": "AGR" }, { "id": "RGD:1310376", "url": "https://alliancegenome.org/gene/RGD:1310376#orthology", "database": "AGR" }, { "id": "FB:FBgn0035761", "url": "https://alliancegenome.org/gene/FB:FBgn0035761#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B0R089", "url": "https://www.uniprot.org/uniprotkb/B0R089" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of cell migration", "id": "GO:0030335", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030335", "evidence": [ { "database": "UniProtKB", "id": "B0R089", "url": "https://www.uniprot.org/uniprotkb/B0R089" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "B0R089", "url": "https://www.uniprot.org/uniprotkb/B0R089" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0R089", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R089" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 201, "start_aa": "Lys", "end_aa": "Asn", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0R0G9-1", "uniprot_ac": "B0R0G9", "uniprot_id": "B0R0G9_DANRE", "mass": { "chemical_mass": 21450.0, "monoisotopic_mass": 21450.0 }, "refseq": { "ac": "NP_001007178", "name": "uncharacterized protein C14orf119 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007178" }, "gene_names": [ { "name": "si:ch211-14a17.11", "type": "recommended", "evidence": [ { "id": "B0R0G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R0G9" } ] }, { "name": "si:ch211-14a17.11", "type": "synonym", "evidence": [ { "id": "NP_001007178", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007178" } ] }, { "name": "si:zc14a17.11", "type": "synonym", "evidence": [ { "id": "NP_001007178", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007178" }, { "id": "B0R0G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R0G9" } ] }, { "name": "zgc:110048", "type": "synonym", "evidence": [ { "id": "NP_001007178", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007178" }, { "id": "B0R0G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R0G9" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C14orf119 homolog", "type": "synonym", "evidence": [ { "id": "B0R0G9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R0G9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C14orf119 homolog", "type": "synonym", "evidence": [ { "id": "NP_001007178", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007178" } ] } ], "function": [], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R0G9", "url": "https://www.uniprot.org/uniprotkb/B0R0G9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-14a17.11", "url": "https://www.uniprot.org/uniprotkb/B0R0G9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030616-582", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-582", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000054292", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000054292", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "368892", "url": "https://www.ncbi.nlm.nih.gov/gene/368892", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028019", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028019", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:368892", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:368892", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "B0R0G9", "url": "https://www.orthodb.org/?gene=B0R0G9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16260", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16260", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16260:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16260:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14969", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14969", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001007178", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001007178", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58GI43", "url": "https://www.uniprot.org/uniprotkb/A0AC58GI43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GI43-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GI43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0R0G9", "url": "https://www.uniprot.org/uniprotkb/B0R0G9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0R0G9-1", "url": "https://www.uniprot.org/uniprotkb/B0R0G9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030616-582", "url": "https://zfin.org/ZDB-GENE-030616-582", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAWFHHALQGSGQPDAPTVEDVSHTQVSMHTITQLGMSDGQGWSTLPSVSISDFPSASGGIVPQRLEALSCTSLSMGSRQDPVPLSFVTLQEQRCVLSWFLGWNVAQKQRFLEDLISKAVPGKVSSLLDQLNTLQVNDRPPNIFECQLRLWTQWFDSWSEEERNAFLNCLEEKDPTFVAFFYNQVAGTAGRD", "length": 192, "header": "tr|B0R0G9-1|B0R0G9_DANRE Isoform 1 of Uncharacterized protein C14orf119 homolog OS=Danio rerio OX=7955 GN=si:ch211-14a17.11 PE=4 SV=1 CANONICAL=B0R0G9-1" }, "isoforms": [ { "isoform_ac": "A0AC58GI43-1", "url": "https://www.uniprot.org/uniprotkb/B0R0G9/entry#A0AC58GI43-1", "sequence": { "sequence": "MGSRQDPVPLSFVTLQEQRCVLSWFLGWNVAQKQRFLEDLISKAVPGKVSSLLDQLNTLQVNDRPPNIFECQLRLWTQWFDSWSEEERNAFLNCLEEKDPTFVAFFYNQVAGTAGRD", "length": 117, "header": "tr|A0AC58GI43-1|A0AC58GI43_DANRE Computationally mapped isoform of Uncharacterized protein C14orf119 homolog isoform X2 OS=Danio rerio OX=7955 GN=si:ch211-14a17.11 PE=4 SV=1 CANONICAL=B0R0G9-1" }, "locus": {} }, { "isoform_ac": "B0R0G9-1", "url": "https://www.uniprot.org/uniprotkb/B0R0G9/entry#B0R0G9-1", "sequence": { "sequence": "MAWFHHALQGSGQPDAPTVEDVSHTQVSMHTITQLGMSDGQGWSTLPSVSISDFPSASGGIVPQRLEALSCTSLSMGSRQDPVPLSFVTLQEQRCVLSWFLGWNVAQKQRFLEDLISKAVPGKVSSLLDQLNTLQVNDRPPNIFECQLRLWTQWFDSWSEEERNAFLNCLEEKDPTFVAFFYNQVAGTAGRD", "length": 192, "header": "tr|B0R0G9-1|B0R0G9_DANRE Isoform 1 of Uncharacterized protein C14orf119 homolog OS=Danio rerio OX=7955 GN=si:ch211-14a17.11 PE=4 SV=1 CANONICAL=B0R0G9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B0R0G9", "url": "https://www.uniprot.org/uniprotkb/B0R0G9" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:368892", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:368892", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GJA3-1", "protein_name": "Similar to human chromosome 14 open reading frame 119", "gene_name": "C16h14orf119", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLESSSTSVPPCFPSVSPSVPDDIANSSPPPMSYITSQEMKCVLQWFASWSGLQWERFLQDLVAKAVLGKMQSLLDGLEQLSVSATSQPPCIFECQLRLWDQWFRSWAEQEGNDCVSQLEVREADFGAKFYQAVAVSAGKN", "length": 142 }, "evidence": [ { "id": "RGD:2324846", "url": "https://alliancegenome.org/gene/RGD:2324846#orthology", "database": "AGR" }, { "id": "MGI:1920893", "url": "https://alliancegenome.org/gene/MGI:1920893#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-582", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-582#orthology", "database": "AGR" }, { "id": "HGNC:20270", "url": "https://alliancegenome.org/gene/HGNC:20270#orthology", "database": "AGR" }, { "id": "FB:FBgn0037739", "url": "https://alliancegenome.org/gene/FB:FBgn0037739#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9JJ93-1", "protein_name": "Uncharacterized protein C14orf119 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLESSSTSVPPCFPSVLPSVPDDIASSSPPPMSYITSQEMKCILYWFASWSGPQRERFLQDLVAKAVPGKLQPLLDALEQLSMSAANRPPCIFECQLRLWDQWFRGWAEQERNEFVRQLEVSEPDFVAKFYQAVAATAGKD", "length": 142 }, "evidence": [ { "id": "RGD:2324846", "url": "https://alliancegenome.org/gene/RGD:2324846#orthology", "database": "AGR" }, { "id": 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automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009292242", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009292242" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R0N8", "url": "https://www.uniprot.org/uniprotkb/B0R0N8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-133n4.9", "url": "https://www.uniprot.org/uniprotkb/B0R0N8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070424-126", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-126", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000071216", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000071216", "database": "Bgee", "categories": [ "Gene 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Classification" ] }, { "id": "B0R0T6", "url": "https://www.orthodb.org/?gene=B0R0T6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR42951", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42951", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR42951:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR42951:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00753", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00753", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001116739", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116739", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0R0T6", "url": "https://www.uniprot.org/uniprotkb/B0R0T6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0R0T6-1", "url": "https://www.uniprot.org/uniprotkb/B0R0T6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-313", "url": "https://zfin.org/ZDB-GENE-081104-313", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAATDWYAHKSLENGVFWIQERFYESGNRANIWLIRGSHQDVVIDTGLGLRSLPEYIQEKSLLGDDAKRKNPLLAIGTHVHFDHSGGLHQFQQVGVHKAEVDALANGDNFETVTWLSDREIVEVPSPGWRARQYRVKAVTPTHILQEGDVINLGDRQLSVLHMPGHSRGSICLHDKESKMLFSGDVVYDGSMIDWLPYSRISDYIHSCERLVEMVDKEEIDQVMPGHYNTFGGKRLHRLASNYIASAGTCHRASTSVVKSIASLALRASNSRSAC", "length": 275, "header": "tr|B0R0T6-1|B0R0T6_DANRE Isoform 1 of Acyl-coenzyme A thioesterase MBLAC2 OS=Danio rerio OX=7955 GN=mblac2 PE=4 SV=1 CANONICAL=B0R0T6-1" }, "isoforms": [ { "isoform_ac": "B0R0T6-1", "url": "https://www.uniprot.org/uniprotkb/B0R0T6/entry#B0R0T6-1", "sequence": { "sequence": "MAATDWYAHKSLENGVFWIQERFYESGNRANIWLIRGSHQDVVIDTGLGLRSLPEYIQEKSLLGDDAKRKNPLLAIGTHVHFDHSGGLHQFQQVGVHKAEVDALANGDNFETVTWLSDREIVEVPSPGWRARQYRVKAVTPTHILQEGDVINLGDRQLSVLHMPGHSRGSICLHDKESKMLFSGDVVYDGSMIDWLPYSRISDYIHSCERLVEMVDKEEIDQVMPGHYNTFGGKRLHRLASNYIASAGTCHRASTSVVKSIASLALRASNSRSAC", "length": 275, "header": "tr|B0R0T6-1|B0R0T6_DANRE Isoform 1 of Acyl-coenzyme A thioesterase MBLAC2 OS=Danio rerio OX=7955 GN=mblac2 PE=4 SV=1 CANONICAL=B0R0T6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 140, "start_aa": "Thr", "end_pos": 140, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr140", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B0R0T6", "url": "https://www.uniprot.org/uniprotkb/B0R0T6" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Shutdown corner, a large deletion mutant isolated from a haploid mutagenesis screen in zebrafish.", "journal": "G3 (Bethesda)", "date": "2022", "authors": "Casey Macaulie A, Hill Jonathon T, Hoshijima Kazuyuki, Bryan Chase D, Gribble Suzanna L, Brown J Thomas, Chien Chi-Bin, Yost H Joseph, Kwan Kristen M", "evidence": [ { "database": "UniProtKB", "id": "B0R0T6", "url": "https://www.uniprot.org/uniprotkb/B0R0T6" } ], "reference": [ { "type": "PubMed", "id": "35079792", "url": "https://glygen.org/publication/PubMed/35079792" } ] } ], "pathway": [ { "id": "dre:563823", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563823", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TD59-1", "protein_name": "Acyl-coenzyme A thioesterase MBLAC2", "gene_name": "MBLAC2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSALEWYAHKSLGDGIFWIQERFYESGNRANIWLVRGSEQDVVIDTGLGLRSLPEYLYSSGLLQDREAKEDAACRPLLAVATHVHFDHSGGLYQFDRVAVHHAEAEALARGDNFETVTWLSDSEVVRAPSPGWRARQFRVQAVQPTLILQDGDVINLGDRQLTVMHMPGHSRGSICLHDKDRKILFSGDVVYDGSLIDWLPYSRISDYIGTCERLIELVDRGLVEKVLPGHFNTFGAERLFRLASNYISKAGICHKVSTFAMRSLASLALRVTNSRTSA", "length": 279 }, "evidence": [ { "id": "B0R0T6", "url": "https://omabrowser.org/oma/group/B0R0T6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A5PJT0-1", "protein_name": "Acyl-coenzyme A thioesterase MBLAC2", "gene_name": "MBLAC2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSALEWYAHKSLGDGIFWIQERFYESGNRANIWLVRGSEQDVVIDTGLGLRSLPEYLYSSGLLRDRAARDNAACRPLLAVATHVHFDHSGGLYQFDRVAVHHAEAEALARGDNFETVTWLSDSEVVRAPSPGWRARQFRVQAVQPTLVLQDGDVINLGDRQLTVMHMPGHSRGSICLHDKDRKILFSGDVVYDGSLIDWLPYSRISDYVGTCERLIELVDRGLVEKVLPGHFNTFGAERLFRLASNYISKAGICHKVSTFAMRSLASLALRVTNSRTSP", "length": 279 }, "evidence": [ { "id": "B0R0T6", "url": "https://omabrowser.org/oma/group/B0R0T6/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "D4A249-1", "protein_name": "Acyl-coenzyme A thioesterase MBLAC2", "gene_name": "Mblac2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSALEWYAHKSLGDGIFWIQERFYESGNRANIWLVRGSEQDVVIDTGLGLRSLPEYLYSSGLLQDCGAKEDAGRRPLLAVATHVHFDHSGGLYQFDQVAVHRAEAEALARGDNFETVTWLSDSEVVRAPSPGWRARQFRVQAVQPTLILQDGDVINLGDRQLTVMHMPGHSRGSICLHDKDRKVLFSGDVVYDGSLIDWLPYSRISDYVGTCERLIELVDRGLVEKVLPGHFNTFGAERLFRLASNYISKAGICHKVSTFAMRSLASLALRVTNPRTSP", "length": 279 }, "evidence": [ { "id": "MGI:1920102", "url": "https://alliancegenome.org/gene/MGI:1920102#orthology", "database": "AGR" }, { "id": "HGNC:33711", "url": "https://alliancegenome.org/gene/HGNC:33711#orthology", "database": "AGR" }, { "id": "B0R0T6", "url": "https://omabrowser.org/oma/group/B0R0T6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HL72-1", "protein_name": "Acyl-coenzyme A thioesterase MBLAC2", "gene_name": "Mblac2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSALEWYAHKSLGDGIFWIQERFYESGNRANIWLVRGSEQDVVIDTGLGLRSLPEYLYSSGLLQDCGAKEDAGRRPLLAVATHVHFDHSGGLYQFDQVAVHRAEAEALARGDNFETVTWLSDSEVVRAPSPGWRARQFRVQAVQPTLILQDGDVINLGDRQLTVMHMPGHSRGSICLHDKDRKVLFSGDVVYDGSLIDWLPYSRISDYVGTCERLIELVDTGLVEKVLPGHFNTFGAERLFRLASNYISKAGICHKVSTFAMRSLASLALRVTNSRTSP", "length": 279 }, "evidence": [ { "id": "B0R0T6", "url": "https://omabrowser.org/oma/group/B0R0T6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q5F336-1", "protein_name": "Acyl-coenzyme A thioesterase MBLAC2", "gene_name": "MBLAC2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSALEWFAHKPLGSGIFWIQERFYESGNRANIWLVRGSQRDLVIDAGLGLRSLPDYLRAAGLLAPPDGAGPRPLLAVATHVHFDHSGGLQHFEEVAVHSAEAAALLRGDNYEAVTWLSDREVTRPPRPGWRARHFCVPPVRPSRLLQEGDVISLGDRQLTVMHMPGHSRGSICLHDREHKILFSGDVVYDGSMIDWLPYSNVSDYVVSCQRLMELVDRGLVEKVLPGHFNMFGAERLYRLASNYISKAGICHKVSTCAMRSIASIALHLTNSRGTSS", "length": 277 }, "evidence": [ { "id": "B0R0T6", "url": "https://omabrowser.org/oma/group/B0R0T6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q68D91-1", "protein_name": "Acyl-coenzyme A thioesterase MBLAC2", "gene_name": "MBLAC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSALEWYAHKSLGDGIFWIQERFYESGNRANIWLVRGSEQDVVIDTGLGLRSLPEYLYSSGLLQDREAKEDAARRPLLAVATHVHFDHSGGLYQFDRVAVHHAEAEALARGDNFETVTWLSDSEVVRTPSPGWRARQFRVQAVQPTLILQDGDVINLGDRQLTVMHMPGHSRGSICLHDKDRKILFSGDVVYDGSLIDWLPYSRISDYVGTCERLIELVDRGLVEKVLPGHFNTFGAERLFRLASNYISKAGICHKVSTFAMRSLASLALRVTNSRTSP", "length": 279 }, "evidence": [ { "id": "MGI:1920102", "url": "https://alliancegenome.org/gene/MGI:1920102#orthology", "database": "AGR" }, { "id": "HGNC:33711", "url": "https://alliancegenome.org/gene/HGNC:33711#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-313", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-313#orthology", "database": "AGR" }, { "id": "B0R0T6", "url": "https://omabrowser.org/oma/group/B0R0T6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BL86-1", "protein_name": "Acyl-coenzyme A thioesterase MBLAC2", "gene_name": "Mblac2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALEWYAHKSLGDGIFWIQERFYESGNRANIWLVRGSEQDVVIDTGLGLRSLPEYLYSSGLLQDCGSKEDAGRRPLLAVATHVHFDHSGGLYQFDQVAVHRAEAEALARGDNFETVTWLSDSEVVRAPSPGWRARQFRVQAVQPTLILQDGDVINLGDRQLTVMHMPGHSRGSICLHDKDRKVLFSGDVVYDGSLIDWLPYSRISDYVGTCERLIELVDRGLVEKVLPGHFNTFGAERLFRLASNYISKAGICHKVSTFAMRSLASLALRVTNPRTSP", "length": 279 }, "evidence": [ { "id": "MGI:1920102", "url": "https://alliancegenome.org/gene/MGI:1920102#orthology", "database": "AGR" }, { "id": "HGNC:33711", "url": "https://alliancegenome.org/gene/HGNC:33711#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-313", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-313#orthology", "database": "AGR" }, { "id": "B0R0T6", "url": "https://omabrowser.org/oma/group/B0R0T6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "beta-lactamase activity", "id": "GO:0008800", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008800", "evidence": [ { "database": "UniProtKB", "id": "B0R0T6", "url": "https://www.uniprot.org/uniprotkb/B0R0T6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0R0T6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R0T6" }, { "id": "SM00849", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00849" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Metallo-beta-lactamase", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 227, "start_aa": "Arg", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 140 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0R111-1", "uniprot_ac": "B0R111", "uniprot_id": "B0R111_DANRE", "mass": { "chemical_mass": 126088.0, "monoisotopic_mass": 126088.0 }, "refseq": { "ac": "NP_001116173", "name": "zinc finger protein 804A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116173" }, "gene_names": [ { "name": "znf804a", "type": "recommended", "evidence": [ { "id": "B0R111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R111" } ] }, { "name": "si:dkeyp-122e7.1", "type": "synonym", "evidence": [ { "id": "NP_001116173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116173" }, { "id": "B0R111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R111" } ] }, { "name": "znf804a", "type": "synonym", "evidence": [ { "id": "NP_001116173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116173" } ] } ], "protein_names": [ { "name": "Zinc finger protein 804A", "type": "synonym", "evidence": [ { "id": "B0R111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R111/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 804A", "type": "synonym", "evidence": [ { "id": "NP_001116173", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116173" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01047992.1, GDQQ01004078.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000009.1. On Jun 5, 2025 this sequence version replaced NP_001116173.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001116173", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116173" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R111", "url": "https://www.uniprot.org/uniprotkb/B0R111" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "znf804a", "url": "https://www.uniprot.org/uniprotkb/B0R111", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-632", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-632", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000027079", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000027079", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "565294", "url": "https://www.ncbi.nlm.nih.gov/gene/565294", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052445", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052445", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565294", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565294", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "THEHWFH", "url": "https://omabrowser.org/oma/group/THEHWFH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0R111", "url": "https://www.orthodb.org/?gene=B0R111", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17614", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17614", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17614:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17614:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27597", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27597", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:B0R111", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:B0R111", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001116173", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116173", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58GEJ6", "url": "https://www.uniprot.org/uniprotkb/A0AC58GEJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GEJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GEJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GEK4", "url": "https://www.uniprot.org/uniprotkb/A0AC58GEK4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GEK4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GEK4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GEL2", "url": "https://www.uniprot.org/uniprotkb/A0AC58GEL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GEL2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GEL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GEL4", "url": "https://www.uniprot.org/uniprotkb/A0AC58GEL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GEL4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GEL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0R111", "url": "https://www.uniprot.org/uniprotkb/B0R111", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0R111-1", "url": "https://www.uniprot.org/uniprotkb/B0R111-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-632", "url": "https://zfin.org/ZDB-GENE-070912-632", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MACYYIVISSTHLSNGHFRNIKGVFRGPLCKNGSKNLDYAEKEKTLAKALEDLKANFYCELCDKQYYKHQEFDNHINSYDHAHKQRLKELKQREFARNVASKSRKNERKQERALRRLHELAEQRREVQCAPGSGPMFKSTTVAVEGSFRESYCDDDAQEENQNCMAQDSGGQIHSSSCGIASKQSPWSYNGRAKKQTFRRKIAFSFSFPKKATVKLESSAAVFCESTEEGSMERSRRQRLRTPPVELDLPGSPMEEKVLKCEEAIYSTGTQQSEHFQKSDSTEIQGSSDIPVAGESPSSTATDLCALLVYSENVPSPAMSPLNTSPFCLNRADIVLESEDSVESLKSSSAESKSETSEDVTEEGSGVTEEGCLAISEPPEKIFSDEPPKNDSSQREEKVEEAPAKSPYAFTKPSQPFFSVLSRDGNTIFQWPSEMVSFTRTEPSLSFSCNPLHFDFKRTRIRRSADTQEMTEPKTDEELSVCSGFKSCHSDKHIEESTATPRNSPSQGAEGKVRKCYQYSSDTESCVRLKTHDKCRHSKDWIHASKRVEEKLRKRDQRHYRSHAKRKRRRRKRRRDRHWETESSMVKSKKFLRRPECVKGLDSQFRGTTSQQVHPLEKSKQSAQNQAEDSSTATVVEEGVGSRRQEAAANVNCSAGCIILSDEFCADGEKVLGNSREKPDNPTAGELTSIEQYPRNRDTSHFHESGSAEGGQEENPNPLVTNRDGACEGQSLKRPCSESLRDRHEFCDSCQSLTDFSDKCTEPTCCEHGTSRKRQRRTQDQDQTPCLAIECPVVHNSVLEEQDKATVESSMKCLVLKGTCDSSNRSDLNSCSIDDGESCTADPQTFSSISSALGHTVVESSDGQQSSSSQINASCTKGSSNLLETDSKLLAEPTKENSESKAAQAPLKNCNKYSAAAQACLLDVRELALQRTEKATQDKSCQHSLQPPPQRFHLGIQAEEKLSRECFHTTGSLFQHSPSFTAPSDSMERHCLLQIQSHGQVLHQQVFPTKLKSVLHRPHLPMSSAVLHPVHLSPSVPSGSITIRHTILQHHAAFLPPQPPIYPQVVPVSRLSLGAEICPPTASPFVASPQVPVVAPPNIHPMTVTFHALPRPAMFSPMLTPHPAVIPLQSLF", "length": 1132, "header": "tr|B0R111-1|B0R111_DANRE Isoform 1 of Zinc finger protein 804A OS=Danio rerio OX=7955 GN=znf804a PE=4 SV=1 CANONICAL=B0R111-1" }, "isoforms": [ { "isoform_ac": "A0AC58GEJ6-1", "url": "https://www.uniprot.org/uniprotkb/B0R111/entry#A0AC58GEJ6-1", "sequence": { "sequence": "MACYYIVISSTHLSNGHFRNIKGVFRGPLCKNGSKNLDYAEKEKTLAKALEDLKANFYCELCDKQYYKHQEFDNHINSYDHAHKQRLKELKQREFARNVASKSRKNERKQERALRRLHELAEQRREVQCAPGSGPMFKSTTVAVEGSFRESYCDDDAQEENQNCMAQDSGGQIHSSSCGIASKQSPWSYNGRAKKQTFRRKIAFSFSFPKKATVKLESSAAVFCESTEEGSMERSRRQRLRTPPVELDLPGSPMEEKVLKCEEAIYSTDTQQSEHFQKSDSTESQGSSDIPVAGESPSSTATDLCALLVYSENVPSPAMSPLNTSPFCLNSADIVLESEDSVESLKSSSAESKSETSKDVTEEGSGVTEEGCLAISEPPEKIFSDEPPKNDSSQREEKVEEAPAKSPYAFTKPSQPFFSVLSRDGNTIFQWPSEMVSFTRTEPSLSFSCNPLHFDFKRTRIRRSADTQEMTEPKTDEELSVCSGFKSCHSDKHIEESTATPRNSPSQGAEGKVRKCYQYSSDTESCVRLKTHDKCRHSKDWIHASKRVEEKLRKRDQRHYRSHAKRKRRRRKRRRDRHWETESSMVKSKKFHRRPECVKGLDSQFRGTTSQQVHPLEKSKQSAQNQAEDSSTATVVEEGVGSRRQEAAANVNCSAGSIILSDEFCADGEKVLGNSREKPDNPTAGELTSIEQYPRNRDTSHFHESGSAEGGQEENPNPLVTNRDGACEGQSLKRPCSESLRDRHEFCDSCQSLTDFSDKCTEPTCCEHGTSRKRQRRTQDQDQTPCLAIECPVVHNSVLEEQDKATVESSMKCLVLKGTCDSSNRSDLNSCSIDDGESCTADPQTFSSISSALGHTVVESSDGQQSSSSQINASCTKGSSNLLETDSKLLAEPTKENSESKAAQAPLKNCNKYSAAAQACLLDVRELALQRTEKATQDKSCQHSLQPPPQRFHLGIQAEEKLSRECFHTTGSLFQHSPSFTAPSDSMERHCLLQIQSHGQVLHQQVFPTKLKSVLHRPHLPMSSAVLHPVHLSPSVPSGSITIRHTILQHHAAFLPPQPPIYPQVVPVSRLSLGAEICPPTASPFVASPQVPVVAPPNIHPMTVTFHALPRPAMFSPMLTPHPAVIPLQSLF", "length": 1132, "header": "tr|A0AC58GEJ6-1|A0AC58GEJ6_DANRE Computationally mapped isoform of Zinc finger protein 804A isoform X1 OS=Danio rerio OX=7955 GN=znf804a PE=4 SV=1 CANONICAL=B0R111-1" }, "locus": {} }, { "isoform_ac": "A0AC58GEK4-1", "url": "https://www.uniprot.org/uniprotkb/B0R111/entry#A0AC58GEK4-1", "sequence": { "sequence": "MKHGSTRDIKQCKIKDYAEKEKTLAKALEDLKANFYCELCDKQYYKHQEFDNHINSYDHAHKQRLKELKQREFARNVASKSRKNERKQERALRRLHELAEQRREVQCAPGSGPMFKSTTVAVEGSFRESYCDDDAQEENQNCMAQDSGGQIHSSSCGIASKQSPWSYNGRAKKQTFRRKIAFSFSFPKKATVKLESSAAVFCESTEEGSMERSRRQRLRTPPVELDLPGSPMEEKVLKCEEAIYSTDTQQSEHFQKSDSTESQGSSDIPVAGESPSSTATDLCALLVYSENVPSPAMSPLNTSPFCLNSADIVLESEDSVESLKSSSAESKSETSKDVTEEGSGVTEEGCLAISEPPEKIFSDEPPKNDSSQREEKVEEAPAKSPYAFTKPSQPFFSVLSRDGNTIFQWPSEMVSFTRTEPSLSFSCNPLHFDFKRTRIRRSADTQEMTEPKTDEELSVCSGFKSCHSDKHIEESTATPRNSPSQGAEGKVRKCYQYSSDTESCVRLKTHDKCRHSKDWIHASKRVEEKLRKRDQRHYRSHAKRKRRRRKRRRDRHWETESSMVKSKKFHRRPECVKGLDSQFRGTTSQQVHPLEKSKQSAQNQAEDSSTATVVEEGVGSRRQEAAANVNCSAGSIILSDEFCADGEKVLGNSREKPDNPTAGELTSIEQYPRNRDTSHFHESGSAEGGQEENPNPLVTNRDGACEGQSLKRPCSESLRDRHEFCDSCQSLTDFSDKCTEPTCCEHGTSRKRQRRTQDQDQTPCLAIECPVVHNSVLEEQDKATVESSMKCLVLKGTCDSSNRSDLNSCSIDDGESCTADPQTFSSISSALGHTVVESSDGQQSSSSQINASCTKGSSNLLETDSKLLAEPTKENSESKAAQAPLKNCNKYSAAAQACLLDVRELALQRTEKATQDKSCQHSLQPPPQRFHLGIQAEEKLSRECFHTTGSLFQHSPSFTAPSDSMERHCLLQIQSHGQVLHQQVFPTKLKSVLHRPHLPMSSAVLHPVHLSPSVPSGSITIRHTILQHHAAFLPPQPPIYPQVVPVSRLSLGAEICPPTASPFVASPQVPVVAPPNIHPMTVTFHALPRPAMFSPMLTPHPAVIPLQSLF", "length": 1110, "header": "tr|A0AC58GEK4-1|A0AC58GEK4_DANRE Computationally mapped isoform of Zinc finger protein 804A isoform X3 OS=Danio rerio OX=7955 GN=znf804a PE=4 SV=1 CANONICAL=B0R111-1" }, "locus": {} }, { "isoform_ac": "A0AC58GEL2-1", "url": "https://www.uniprot.org/uniprotkb/B0R111/entry#A0AC58GEL2-1", "sequence": { "sequence": "MFKSTTVAVEGSFRESYCDDDAQEENQNCMAQDSGGQIHSSSCGIASKQSPWSYNGRAKKQTFRRKIAFSFSFPKKATVKLESSAAVFCESTEEGSMERSRRQRLRTPPVELDLPGSPMEEKVLKCEEAIYSTDTQQSEHFQKSDSTESQGSSDIPVAGESPSSTATDLCALLVYSENVPSPAMSPLNTSPFCLNSADIVLESEDSVESLKSSSAESKSETSKDVTEEGSGVTEEGCLAISEPPEKIFSDEPPKNDSSQREEKVEEAPAKSPYAFTKPSQPFFSVLSRDGNTIFQWPSEMVSFTRTEPSLSFSCNPLHFDFKRTRIRRSADTQEMTEPKTDEELSVCSGFKSCHSDKHIEESTATPRNSPSQGAEGKVRKCYQYSSDTESCVRLKTHDKCRHSKDWIHASKRVEEKLRKRDQRHYRSHAKRKRRRRKRRRDRHWETESSMVKSKKFHRRPECVKGLDSQFRGTTSQQVHPLEKSKQSAQNQAEDSSTATVVEEGVGSRRQEAAANVNCSAGSIILSDEFCADGEKVLGNSREKPDNPTAGELTSIEQYPRNRDTSHFHESGSAEGGQEENPNPLVTNRDGACEGQSLKRPCSESLRDRHEFCDSCQSLTDFSDKCTEPTCCEHGTSRKRQRRTQDQDQTPCLAIECPVVHNSVLEEQDKATVESSMKCLVLKGTCDSSNRSDLNSCSIDDGESCTADPQTFSSISSALGHTVVESSDGQQSSSSQINASCTKGSSNLLETDSKLLAEPTKENSESKAAQAPLKNCNKYSAAAQACLLDVRELALQRTEKATQDKSCQHSLQPPPQRFHLGIQAEEKLSRECFHTTGSLFQHSPSFTAPSDSMERHCLLQIQSHGQVLHQQVFPTKLKSVLHRPHLPMSSAVLHPVHLSPSVPSGSITIRHTILQHHAAFLPPQPPIYPQVVPVSRLSLGAEICPPTASPFVASPQVPVVAPPNIHPMTVTFHALPRPAMFSPMLTPHPAVIPLQSLF", "length": 997, "header": "tr|A0AC58GEL2-1|A0AC58GEL2_DANRE Computationally mapped isoform of Zinc finger protein 804A isoform X4 OS=Danio rerio OX=7955 GN=znf804a PE=4 SV=1 CANONICAL=B0R111-1" }, "locus": {} }, { "isoform_ac": "A0AC58GEL4-1", "url": "https://www.uniprot.org/uniprotkb/B0R111/entry#A0AC58GEL4-1", "sequence": { "sequence": "MRKAFLEHVGRSLMKHGSTRDIKQCKIKDYAEKEKTLAKALEDLKANFYCELCDKQYYKHQEFDNHINSYDHAHKQRLKELKQREFARNVASKSRKNERKQERALRRLHELAEQRREVQCAPGSGPMFKSTTVAVEGSFRESYCDDDAQEENQNCMAQDSGGQIHSSSCGIASKQSPWSYNGRAKKQTFRRKIAFSFSFPKKATVKLESSAAVFCESTEEGSMERSRRQRLRTPPVELDLPGSPMEEKVLKCEEAIYSTDTQQSEHFQKSDSTESQGSSDIPVAGESPSSTATDLCALLVYSENVPSPAMSPLNTSPFCLNSADIVLESEDSVESLKSSSAESKSETSKDVTEEGSGVTEEGCLAISEPPEKIFSDEPPKNDSSQREEKVEEAPAKSPYAFTKPSQPFFSVLSRDGNTIFQWPSEMVSFTRTEPSLSFSCNPLHFDFKRTRIRRSADTQEMTEPKTDEELSVCSGFKSCHSDKHIEESTATPRNSPSQGAEGKVRKCYQYSSDTESCVRLKTHDKCRHSKDWIHASKRVEEKLRKRDQRHYRSHAKRKRRRRKRRRDRHWETESSMVKSKKFHRRPECVKGLDSQFRGTTSQQVHPLEKSKQSAQNQAEDSSTATVVEEGVGSRRQEAAANVNCSAGSIILSDEFCADGEKVLGNSREKPDNPTAGELTSIEQYPRNRDTSHFHESGSAEGGQEENPNPLVTNRDGACEGQSLKRPCSESLRDRHEFCDSCQSLTDFSDKCTEPTCCEHGTSRKRQRRTQDQDQTPCLAIECPVVHNSVLEEQDKATVESSMKCLVLKGTCDSSNRSDLNSCSIDDGESCTADPQTFSSISSALGHTVVESSDGQQSSSSQINASCTKGSSNLLETDSKLLAEPTKENSESKAAQAPLKNCNKYSAAAQACLLDVRELALQRTEKATQDKSCQHSLQPPPQRFHLGIQAEEKLSRECFHTTGSLFQHSPSFTAPSDSMERHCLLQIQSHGQVLHQQVFPTKLKSVLHRPHLPMSSAVLHPVHLSPSVPSGSITIRHTILQHHAAFLPPQPPIYPQVVPVSRLSLGAEICPPTASPFVASPQVPVVAPPNIHPMTVTFHALPRPAMFSPMLTPHPAVIPLQSLF", "length": 1123, "header": "tr|A0AC58GEL4-1|A0AC58GEL4_DANRE Computationally mapped isoform of Zinc finger protein 804A isoform X2 OS=Danio rerio OX=7955 GN=znf804a PE=4 SV=1 CANONICAL=B0R111-1" }, "locus": {} }, { "isoform_ac": "B0R111-1", "url": "https://www.uniprot.org/uniprotkb/B0R111/entry#B0R111-1", "sequence": { "sequence": "MACYYIVISSTHLSNGHFRNIKGVFRGPLCKNGSKNLDYAEKEKTLAKALEDLKANFYCELCDKQYYKHQEFDNHINSYDHAHKQRLKELKQREFARNVASKSRKNERKQERALRRLHELAEQRREVQCAPGSGPMFKSTTVAVEGSFRESYCDDDAQEENQNCMAQDSGGQIHSSSCGIASKQSPWSYNGRAKKQTFRRKIAFSFSFPKKATVKLESSAAVFCESTEEGSMERSRRQRLRTPPVELDLPGSPMEEKVLKCEEAIYSTGTQQSEHFQKSDSTEIQGSSDIPVAGESPSSTATDLCALLVYSENVPSPAMSPLNTSPFCLNRADIVLESEDSVESLKSSSAESKSETSEDVTEEGSGVTEEGCLAISEPPEKIFSDEPPKNDSSQREEKVEEAPAKSPYAFTKPSQPFFSVLSRDGNTIFQWPSEMVSFTRTEPSLSFSCNPLHFDFKRTRIRRSADTQEMTEPKTDEELSVCSGFKSCHSDKHIEESTATPRNSPSQGAEGKVRKCYQYSSDTESCVRLKTHDKCRHSKDWIHASKRVEEKLRKRDQRHYRSHAKRKRRRRKRRRDRHWETESSMVKSKKFLRRPECVKGLDSQFRGTTSQQVHPLEKSKQSAQNQAEDSSTATVVEEGVGSRRQEAAANVNCSAGCIILSDEFCADGEKVLGNSREKPDNPTAGELTSIEQYPRNRDTSHFHESGSAEGGQEENPNPLVTNRDGACEGQSLKRPCSESLRDRHEFCDSCQSLTDFSDKCTEPTCCEHGTSRKRQRRTQDQDQTPCLAIECPVVHNSVLEEQDKATVESSMKCLVLKGTCDSSNRSDLNSCSIDDGESCTADPQTFSSISSALGHTVVESSDGQQSSSSQINASCTKGSSNLLETDSKLLAEPTKENSESKAAQAPLKNCNKYSAAAQACLLDVRELALQRTEKATQDKSCQHSLQPPPQRFHLGIQAEEKLSRECFHTTGSLFQHSPSFTAPSDSMERHCLLQIQSHGQVLHQQVFPTKLKSVLHRPHLPMSSAVLHPVHLSPSVPSGSITIRHTILQHHAAFLPPQPPIYPQVVPVSRLSLGAEICPPTASPFVASPQVPVVAPPNIHPMTVTFHALPRPAMFSPMLTPHPAVIPLQSLF", "length": 1132, "header": "tr|B0R111-1|B0R111_DANRE Isoform 1 of Zinc finger protein 804A OS=Danio rerio OX=7955 GN=znf804a PE=4 SV=1 CANONICAL=B0R111-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Comprehensive expression map of transcription regulators in the adult zebrafish telencephalon reveals distinct neurogenic niches.", "journal": "J. Comp. Neurol.", "date": "2015", "authors": "Diotel Nicolas, Rodriguez Viales Rebecca, Armant Olivier, M\u00e4rz Martin, Ferg Marco, Rastegar Sepand, Str\u00e4hle Uwe", "evidence": [ { "database": "UniProtKB", "id": "B0R111", "url": "https://www.uniprot.org/uniprotkb/B0R111" } ], "reference": [ { "type": "PubMed", "id": "25556858", "url": "https://glygen.org/publication/PubMed/25556858" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0R111", "url": "https://www.uniprot.org/uniprotkb/B0R111" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B0R111", "url": "https://www.uniprot.org/uniprotkb/B0R111" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Phenotypic Landscape of Schizophrenia-Associated Genes Defines Candidates and Their Shared Functions.", "journal": "Cell", "date": "2019", "authors": "Thyme Summer B, Pieper Lindsey M, Li Eric H, Pandey Shristi, Wang Yiqun, Morris Nathan S, Sha Carrie, Choi Joo Won, Herrera Kristian J, Soucy Edward R, Zimmerman Steve, Randlett Owen, Greenwood Joel, McCarroll Steven A, Schier Alexander F", "evidence": [ { "database": "UniProtKB", "id": "B0R111", "url": "https://www.uniprot.org/uniprotkb/B0R111" } ], "reference": [ { "type": "PubMed", "id": "30929901", "url": "https://glygen.org/publication/PubMed/30929901" } ] }, { "title": "Transcriptional regulators with broad expression in the zebrafish spinal cord.", "journal": "Dev. Dyn.", "date": "2024", "authors": "England Samantha J, Campbell Paul C, Banerjee Santanu, Bates Richard L, Grieb Ginny, Fancher William F, Lewis Katharine E", "evidence": [ { "database": "UniProtKB", "id": "B0R111", "url": "https://www.uniprot.org/uniprotkb/B0R111" } ], "reference": [ { "type": "PubMed", "id": "38850245", "url": "https://glygen.org/publication/PubMed/38850245" } ] } ], "pathway": [ { "id": "dre:565294", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565294", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YSD3-1", "protein_name": "Zinc finger protein 804A", "gene_name": "ZNF804A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPRGSREGPHRPGSPGPMECYYIVISSAHLSNGHFRNIKGVFRGPLSKNGDKTLGQILGHVHGPSRDTEIREGVVMHWNRLSREVVGSPSLEVFKNCGDGALRDTVDTDYAEKKNTIAKALEDLKANFYCALCDKQYYKHQEFDNHINSYDHAHKQRLKELKQREFARNVASKSRKDERKQEKALQRLHKLAELRKVTTCAPGSGPMFKSTTVTVRDNSSDIPQSTAIDSSSKQDFSCTLMHNTQNCKDATSDISSTPENACSNASRTNKFGDQVHGAQGHRVGFSFAFPKKAVVKLESSAAVFYEYNDETSMEHGLSRRSRFIPGACNPLSPSATEIVLCPEEKQNCLHPLVEKCTDAAEDPENQESKELVSEENRELENPVLIPAVSNSKQLLCSDMEGCNTDVSTADVPGQTLSVVVDSAQVLPQDCSSCELLGNGAVVQAAVEDCSSLQDTAEDNGKDGNSDLFTVETEIKKLGTEVLVPSHSEDGTRVPQSKLDTRKKSCEPFVPVLSKHGSNILQWPSEMLIYTSTDPSISYSCNPLYFDFRSSKASDSQEKPKHQANVPNLHHATESNHSLVSDFTNKPTSECGDPEAEINKNACDYTVPLVSDVSLIRNSDLAKNQHKVALGESFRIKKLEKYHISKNHLRQNAVIDEKYNKVRIKDSHEKWLHRSRKRKRRRKLCHCHHHHYHPCGEATIAEMEISSVIEKEMSYRDENKHQHLQNNPEKCRYDAGNIWIATDEIQQSHQKADTENGHKRVMATSDHLHGGRGLCDICHAKSRDQRSDCKPLHRKRKASSRRQLRQLARTCRRHNCLCSKTCCSWKVRRLSCSPEHKCLGHCSEEKSPGHHQSIKRGYSFLTDEPESSHRKRRQHAYSCSSDESLYREACLAEEYFRQASASGMHHKAKSKHRRRKTRISHVCIDRNERSEASRPCKENSASSTINVLGELSTQDNTGVTIVNSKADLAEEKDEIMQLEENKASLPMGGAHVLEQDKPTDCAAPESMLGILSDAATHCAASVPEQGAPAAASTQDAPKDEKKNENVNSHESQARYKAPPPTRHLDRAPPKSVLCHYELAESLPHEKINEVTSDWVQCNSGIFNSPPPLPFKEAHLNSHTFLATEQLIAPFTLPDQTLIFPPDNHEKFKDLPSEAYQQLVQQNMLANKVKFTLPPPAMQPPSSPLQPLPLQPPLCSTSVTTIHHTVLQQHAAASALKALQPHQHFLSQVPALARAPLPHLPVGPRLCPGGPAAFVAPPHLPLVPPSVLQPAPLAFSPLPHAVFPSLLSPHPAVLPLQPLF", "length": 1298 }, "evidence": [ { "id": "B0R111", "url": "https://omabrowser.org/oma/group/B0R111/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2AKY4-1", "protein_name": "Zinc finger protein 804A", "gene_name": "Znf804a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MECYYIVISSTHLSNGHFRNIKGVFRGPLSKNGNKTLDYAEKENTIAKALEDLKANFYCELCDKQYYKHQEFDNHINSYDHAHKQRLKELKQREFARNVASKSRKDERKQEKALQRLHKLAELRKETVCAPGSGPMFKSTTVTVRENLNDVSQRESVDPINNQQDLIPSEEKERDGTTALAETETASNCTANNCQIGDQSQAVHRHRIGFSFAFPKKATVKLESCSAAAFSEYSDESSMEKEFSRKTRFVPSTSHLQLPPPTCELLSSEEKGNSPPPEAMCTDKATAQTEERKITSNENNTLLTSSFCQLQHYIPTCSEADTCQNLAPFEDQLPMEAVIVNEDGPVSKSNPNIIEKNPTVPNDRTSAQMTTEENITINDVTKMETRNKIDHEPLTPSSTIEESIRLQKRPDLCKRQCDPFVPVLNKLGSTVLQWPSEMLAYTTTEPSISYSCNPLCFDFKSTKLNNNQDKNKLTLNDLFSEQKEDCCKGAHADCKDVPIARVTNDETGHSKNDYPQVTTLSPVHVLSNGCDLGQNENVGQRYKHISCTNRQTNKYKFTRCQIKRDMLNEKYDKMRLKETREHWFHKSRRKKKRRKLCRYHPGKSSKEPEGSGKTERSRQRTDEARKNPREPVLEKHPRSPERASDLHQLPDERPKAASTHLGEKETMNTTVNTESNDAAPGSQNCGGKNATVVNEQAKPLVIHSVKQNLTYVRTYCCWKARTSRYQEDDGSLASQSNVKGPTQNQPVKRGYSSLTNDSERIHRKRRQHSCSYSSDESLNQQHHLGEYLKPLSTSLISCQPKKKRRRKRSRLHIGDGTTKMKGNSNYPMKCSSLSQPDELAKDCIKEDINPQENVSIEKNSEQTEQTEIKGMLHPYNPLLSEPSGEGEHSVTETTPCDSSQTSNDLATPVNVTRDPSNSTTDNTLLEHNQRSQTTNSNEKQTPFKVTNPERNFRHSQAKSYICRYELAETIPQGKTNEASTEWLCYNSGILNTQPPLQFKEAHVSGHAFVTTEQILAPLPLPEQALLIPLENHDKLKHLPCEVYQHIIQPNMLTNKVKFTFPPPPLPPPSTPVQPLPLQRPFCSTSVTTIHHTVLQHHAAAAAAAAAAAAAGTFKVLQPHQQFLPQVPALARTSIPQISVGTVGPRLCPGGQPALVASPQMPIIPASVLHPSPLAFPPLPHSFFPSLLSPHPTVIPLQPLF", "length": 1200 }, "evidence": [ { "id": "HGNC:21711", "url": "https://alliancegenome.org/gene/HGNC:21711#orthology", "database": "AGR" }, { "id": "B0R111", "url": "https://omabrowser.org/oma/group/B0R111/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1M078-1", "protein_name": "Zinc finger protein 804A", "gene_name": "Zfp804a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MECYYIVISSTHLSNGHFRNIKGVFRGPLSKNGNKTLDYAEKENTIAKALEDLKANFYCELCDKQYYKHQEFDNHINSYDHAHKQRLKELKQREFARNVASKSRKDERKQEKALQRLHKLAELRKETVCAPGSGPMFKSTTVTVKENLNDVSRRESVDPVDNQQDVVHSDEKGRGGSTASAETETASNCTANNCQTGDQIQAIHRHRIGFSFAFPKKASVKLESSSAAAFSEYSDESSVEKEFSRKTRFVPSTCHLQLSSPTCELLSSEDKANSSPPEVMCLDKAAAQTEEMKITSTENNTVLTTSFCQLQLPACSDEDTCQNSAPFEDQASMETVIVNEDRPVNKSNPDIIEKNPTAPNDCTSAQMSTEENITINDVAKMETRNKIGHEPLTPTSTAEESIRFQKRPDLCKRQCDPFVPVLNKLGSTVLQWPSEMLAYTTTEPSISYSCNPLCFDFRSTKLNNNQEKSKLTLNDPFSQQKEDCCKRADCSEVPTGRVTSDESGSSKNDSPQVTTYSAAHVVSNGCDLGQNENVAQRYKHMSCTNRKTYKYNFTRSQIKRNTLNEKYNKIRLKETHEHWFHKSRRKKKRRKLCRYHRGKSAKEPEGSCKTETDRQRADETRKNPLEPVLERQSGSPERLSDLHQLADERPKTAPTHLVENENTDTTRNTESNDNALDSQNHGGENAIVVNEQANQAMIHSGKQNLTYVRTYCCWKARTPRCQEDDRCFVSQSDVKDPTQNQPVKRGYSSLTNDTERIHRKRRQHSCSYSSDENSNQQSHLGEEYLRPSNASLTSSQPKKKRRRKRSRLHIGDRTSKIKDNSNYSTMCRSSLSHPDGFAKEDIKEDTKPQENRSIKKSSEHTEQTEDKVIFHPPNPFPSEASGKDEHSVTETTPCVSSQASSDLATPVSVTGDPPNGTTDNTLLEHSQRSQTTHRNEKQIPLKVPNTERNFRHPPAKSYICRYELAETIPQGKTTESSTEWLCYNSGILNTQPPLQFKEAQVSGHAFVTTEEILAPLPLPEQALLIPLENHDKLKHLPCEVYQHIIQPTMLTNKVKFTFPPAPLPPPSTPVQPLPLQRPFCSTSVTTIHHTVLQHHAAAAAAAAAAAAAGTFKVLQPHQQFLPQVPPLARTSIPQISVGTVGPRLCPGRQPALVASPQMPIIPASVLHPSHLTFPPLPHAIFPSLLSPHPTVIPLQPLF", "length": 1198 }, "evidence": [ { "id": "HGNC:21711", "url": "https://alliancegenome.org/gene/HGNC:21711#orthology", "database": "AGR" }, { "id": "B0R111", "url": "https://omabrowser.org/oma/group/B0R111/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z570-1", "protein_name": "Zinc finger protein 804A", "gene_name": "ZNF804A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MECYYIVISSTHLSNGHFRNIKGVFRGPLSKNGNKTLDYAEKENTIAKALEDLKANFYCELCDKQYYKHQEFDNHINSYDHAHKQRLKELKQREFARNVASKSRKDERKQEKALQRLHKLAELRKETVCAPGSGPMFKSTTVTVRENCNEISQRVVVDSVNNQQDFKYTLIHSEENTKDATTVAEDPESANNYTAKNNQVGDQAQGIHRHKIGFSFAFPKKASVKLESSAAAFSEYSDDASVGKGFSRKSRFVPSACHLQQSSPTDVLLSSEEKTNSFHPPEAMCRDKETVQTQEIKEVSSEKDALLLPSFCKFQLQLSSDADNCQNSVPLADQIPLESVVINEDIPVSGNSFELLGNKSTVLDMSNDCISVQATTEENVKHNEASTTEVENKNGPETLAPSNTEEVNITIHKKTNFCKRQCEPFVPVLNKHRSTVLQWPSEMLVYTTTKPSISYSCNPLCFDFKSTKVNNNLDKNKPDLKDLCSQQKQEDICMGPLSDYKDVSTEGLTDYEIGSSKNKCSQVTPLLADDILSSSCDSGKNENTGQRYKNISCKIRETEKYNFTKSQIKQDTLDEKYNKIRLKETHEYWFHKSRRKKKRKKLCQHHHMEKTKESETRCKMEAENSYTENAGKYLLEPISEKQYLAAEQLLDSHQLLDKRPKSESISLSDNEEMCKTWNTEYNTYDTISSKNHCKKNTILLNGQSNATMIHSGKHNLTYSRTYCCWKTKMSSCSQDHRSLVLQNDMKHMSQNQAVKRGYNSVMNESERFYRKRRQHSHSYSSDESLNRQNHLPEEFLRPPSTSVAPCKPKKKRRRKRGRFHPGFETLELKENTDYPVKDNSSLNPLDRLISEDKKEKMKPQEVAKIERNSEQTNQLRNKLSFHPNNLLPSETNGETEHLEMETTSGELSDVSNDPTTSVCVASAPTKEAIDNTLLEHKERSENINLNEKQIPFQVPNIERNFRQSQPKSYLCHYELAEALPQGKMNETPTEWLRYNSGILNTQPPLPFKEAHVSGHTFVTAEQILAPLALPEQALLIPLENHDKFKNVPCEVYQHILQPNMLANKVKFTFPPAALPPPSTPLQPLPLQQSLCSTSVTTIHHTVLQQHAAAAAAAAAAAAAGTFKVLQPHQQFLSQIPALTRTSLPQLSVGPVGPRLCPGNQPTFVAPPQMPIIPASVLHPSHLAFPSLPHALFPSLLSPHPTVIPLQPLF", "length": 1209 }, "evidence": [ { "id": "HGNC:21711", "url": "https://alliancegenome.org/gene/HGNC:21711#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-632", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-632#orthology", "database": "AGR" }, { "id": "B0R111", "url": "https://omabrowser.org/oma/group/B0R111/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0R111", "url": "https://www.uniprot.org/uniprotkb/B0R111" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B0R111", "url": "https://www.uniprot.org/uniprotkb/B0R111" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 323, "end_pos": 325, "annotation": "n_glycosylation_sequon" }, { "start_pos": 32, "end_pos": 34, "annotation": "n_glycosylation_sequon" }, { "start_pos": 390, "end_pos": 392, "annotation": "n_glycosylation_sequon" }, { "start_pos": 652, "end_pos": 654, "annotation": "n_glycosylation_sequon" }, { "start_pos": 824, "end_pos": 826, "annotation": "n_glycosylation_sequon" }, { "start_pos": 872, "end_pos": 874, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0R111", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R111" }, { "id": "PS00028", "database": "PROSITE", "url": "https://prosite.expasy.org/PS00028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 81, "start_aa": "Cys", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 323, "end_pos": 325 }, { "start_pos": 32, "end_pos": 34 }, { "start_pos": 390, "end_pos": 392 }, { "start_pos": 652, "end_pos": 654 }, { "start_pos": 824, "end_pos": 826 }, { "start_pos": 872, "end_pos": 874 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0R125-1", "uniprot_ac": "B0R125", "uniprot_id": "B0R125_DANRE", "mass": { "chemical_mass": 20130.0, "monoisotopic_mass": 20130.0 }, "refseq": { "ac": "NP_001188392", "name": "cysteine-rich hydrophobic domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188392" }, "gene_names": [ { "name": "chic1", "type": "recommended", "evidence": [ { "id": "B0R125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R125" } ] }, { "name": "chic1", "type": "synonym", "evidence": [ { "id": "NP_001188392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188392" } ] }, { "name": "wu:fj33g02", "type": "synonym", "evidence": [ { "id": "NP_001188392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188392" }, { "id": "B0R125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R125" } ] } ], "protein_names": [ { "name": "Cysteine-rich hydrophobic domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "B0R125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R125/entry#names_and_taxonomy" } ] }, { "name": "cysteine-rich hydrophobic domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001188392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188392" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC110112.1, GDQQ01026548.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Jun 25, 2025 this sequence version replaced NP_001188392.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001188392", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188392" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0R125", "url": "https://www.uniprot.org/uniprotkb/B0R125" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "chic1", "url": "https://www.uniprot.org/uniprotkb/B0R125", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-7763", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7763", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000053166", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000053166", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "564524", "url": "https://www.ncbi.nlm.nih.gov/gene/564524", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019383", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019383", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039735", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039735", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564524", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564524", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NYSMTEY", "url": "https://omabrowser.org/oma/group/NYSMTEY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0R125", "url": "https://www.orthodb.org/?gene=B0R125", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13005", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13005", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13005:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13005:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10256", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10256", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001188392", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188392", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0R125", "url": "https://www.uniprot.org/uniprotkb/B0R125", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0R125-1", "url": "https://www.uniprot.org/uniprotkb/B0R125-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-7763", "url": "https://zfin.org/ZDB-GENE-030131-7763", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSVLLPNMADFDTIYELEEEDERIVSEEHLVRYCPEPVVMRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSINRVNACLKKNLPVNVKWLLCGCLCCCCTVGCSLWPVICLNKRTRRSIQKLLEWENNRLYHKLGLHWKLSKRKCESNNMMEYVILIEFLPKYPIFRPD", "length": 173, "header": "tr|B0R125-1|B0R125_DANRE Isoform 1 of Cysteine-rich hydrophobic domain-containing protein 1 OS=Danio rerio OX=7955 GN=chic1 PE=4 SV=1 CANONICAL=B0R125-1" }, "isoforms": [ { "isoform_ac": "B0R125-1", "url": "https://www.uniprot.org/uniprotkb/B0R125/entry#B0R125-1", "sequence": { "sequence": "MSVLLPNMADFDTIYELEEEDERIVSEEHLVRYCPEPVVMRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSINRVNACLKKNLPVNVKWLLCGCLCCCCTVGCSLWPVICLNKRTRRSIQKLLEWENNRLYHKLGLHWKLSKRKCESNNMMEYVILIEFLPKYPIFRPD", "length": 173, "header": "tr|B0R125-1|B0R125_DANRE Isoform 1 of Cysteine-rich hydrophobic domain-containing protein 1 OS=Danio rerio OX=7955 GN=chic1 PE=4 SV=1 CANONICAL=B0R125-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes.", "journal": "Nature", "date": "2003", "authors": "Davidson Alan J, Ernst Patricia, Wang Yuan, Dekens Marcus P S, Kingsley Paul D, Palis James, Korsmeyer Stanley J, Daley George Q, Zon Leonard I", "evidence": [ { "database": "UniProtKB", "id": "B0R125", "url": "https://www.uniprot.org/uniprotkb/B0R125" } ], "reference": [ { "type": "PubMed", "id": "13679919", "url": "https://glygen.org/publication/PubMed/13679919" } ] }, { "title": "A consensus Oct1 binding site is required for the activity of the Xenopus Cdx4 promoter.", "journal": "Dev. Biol.", "date": "2005", "authors": "Reece-Hoyes John S, Keenan Iain D, Pownall Mary Elizabeth, Isaacs Harry V", "evidence": [ { "database": "UniProtKB", "id": "B0R125", "url": "https://www.uniprot.org/uniprotkb/B0R125" } ], "reference": [ { "type": "PubMed", "id": "15950614", "url": "https://glygen.org/publication/PubMed/15950614" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0R125", "url": "https://www.uniprot.org/uniprotkb/B0R125" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:564524", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564524", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1W1Z0-1", "protein_name": "Cysteine rich hydrophobic domain 1", "gene_name": "CHIC1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEVEETPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLLEWENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD", "length": 223 }, "evidence": [ { "id": "B0R125", "url": "https://omabrowser.org/oma/group/B0R125/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8M1PFN1-1", "protein_name": "Cysteine-rich hydrophobic domain-containing protein 2", "gene_name": "chic2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMEDFDEIYEEEEEEEEDEDRAAEEQLLKYAPDPVVVRGSGHVTVFGLSNKFESEFPSALTGKVAPEEFKSSINRVNSCLRKALPVNVRWLLCGCLCCCCTLGFSLWPVICLSKRTRRSIEKLLEWENSRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKIPIFRPD", "length": 170 }, "evidence": [ { "id": "FB:FBgn0046247", "url": "https://alliancegenome.org/gene/FB:FBgn0046247#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3V6A1-1", "protein_name": "Cysteine-rich hydrophobic domain 2", "gene_name": "Chic2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLRKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD", "length": 165 }, "evidence": [ { "id": "FB:FBgn0046247", "url": "https://alliancegenome.org/gene/FB:FBgn0046247#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70537-1", "protein_name": "Testis-specific protein TSX", "gene_name": "Tsx", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEEQEPKTSEAEYGTMDFPEFENEEEWLFKVLGIKPRPSSDLDDADKQEDEPLGHTEFLRLQDILQEDKVSSTNDSDTCQAGYTEENDEASHSDSDIDDNVNVIIGDIKANSSMYMEMFTNMNSQADQDLKLTESDNAMYPTD", "length": 144 }, "evidence": [ { "id": "HGNC:1934", "url": "https://alliancegenome.org/gene/HGNC:1934#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7763", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7763#orthology", "database": "AGR" }, { "id": "RGD:1589722", "url": "https://alliancegenome.org/gene/RGD:1589722#orthology", "database": "AGR" }, { "id": "RGD:3914", "url": "https://alliancegenome.org/gene/RGD:3914#orthology", "database": "AGR" }, { "id": "MGI:1344694", "url": "https://alliancegenome.org/gene/MGI:1344694#orthology", "database": "AGR" }, { "id": "FB:FBgn0046247", "url": "https://alliancegenome.org/gene/FB:FBgn0046247#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P70675-1", "protein_name": "Testis-specific protein TSX", "gene_name": "Tsx", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEKQSPKTSEAECSAMDLPEFEDEENWLFKVLGFQPGPSSALDDDTDDQADEPLSAAEFLHLQDILQEDRVSSTDDEDTCQAGCTEDDETSHSDRDIDNNVKVITGNIKASPSMYMEMFTDQNPQADQDLEETESDGAMNPTD", "length": 144 }, "evidence": [ { "id": "RGD:3914", "url": "https://alliancegenome.org/gene/RGD:3914#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q0KI06-1", "protein_name": "Golgin subfamily A member 7/ERF4 domain-containing protein", "gene_name": "Dmel\\CG5938", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSFSDFDAIYEDEQLDELEHFQDQTVAPVQEPIIIRGAGNMTVFGLSNRFNAEFPCGLLSRVAPEEFKATVGRINGVLKKSLPVNVKWLFCGCVCCCCTLGCSLWPVICLSKRTQLTLDKLFEWENNHLYHKLGLHWRLHKQQCDSNSMMEYVILIEFIPKTPIYRPD", "length": 168 }, "evidence": [ { "id": "HGNC:1934", "url": "https://alliancegenome.org/gene/HGNC:1934#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7763", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7763#orthology", "database": "AGR" }, { "id": "RGD:1589722", "url": "https://alliancegenome.org/gene/RGD:1589722#orthology", "database": "AGR" }, { "id": "RGD:3914", "url": "https://alliancegenome.org/gene/RGD:3914#orthology", "database": "AGR" }, { "id": "MGI:1344694", "url": "https://alliancegenome.org/gene/MGI:1344694#orthology", "database": "AGR" }, { "id": "FB:FBgn0046247", "url": "https://alliancegenome.org/gene/FB:FBgn0046247#orthology", "database": "AGR" }, { "id": "B0R125", "url": "https://omabrowser.org/oma/group/B0R125/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5VXU3-1", "protein_name": "Cysteine-rich hydrophobic domain-containing protein 1", "gene_name": "CHIC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSILLPNMAEFDTISELEEEEEEEAATSSSSPSSSSSVSGPDDDEEDEEEEEEEEEEEEEEEEEEEEEAPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNACLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLIEWENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD", "length": 224 }, "evidence": [ { "id": "HGNC:1934", "url": "https://alliancegenome.org/gene/HGNC:1934#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7763", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7763#orthology", "database": "AGR" }, { "id": "RGD:1589722", "url": "https://alliancegenome.org/gene/RGD:1589722#orthology", "database": "AGR" }, { "id": "RGD:3914", "url": "https://alliancegenome.org/gene/RGD:3914#orthology", "database": "AGR" }, { "id": "MGI:1344694", "url": "https://alliancegenome.org/gene/MGI:1344694#orthology", "database": "AGR" }, { "id": "FB:FBgn0046247", "url": "https://alliancegenome.org/gene/FB:FBgn0046247#orthology", "database": "AGR" }, { "id": "B0R125", "url": "https://omabrowser.org/oma/group/B0R125/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CBW7-1", "protein_name": "Cysteine-rich hydrophobic domain-containing protein 1", "gene_name": "Chic1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSILLPNMAEFDTISELEEEEEAATSSSSPSSSPSSSSSSSVSGPDEDEEDEEEEEEEDEEEEDEEEEEEEVPPPPRVVSEEHLRRYAPDPVLVRGAGHITVFGLSNKFDTEFPSVLTGKVAPEEFKTSIGRVNSCLKKALPVNVKWLLCGCLCCCCTLGCSLWPVICLNKRTRRSIQKLLEWENNRLYHKLALHWKLTKRKCETSNMMEYVILIEFLPKYPIFRPD", "length": 227 }, "evidence": [ { "id": "HGNC:1934", "url": "https://alliancegenome.org/gene/HGNC:1934#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7763", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7763#orthology", "database": "AGR" }, { "id": "RGD:1589722", "url": "https://alliancegenome.org/gene/RGD:1589722#orthology", "database": "AGR" }, { "id": "RGD:3914", "url": "https://alliancegenome.org/gene/RGD:3914#orthology", "database": "AGR" }, { "id": "MGI:1344694", "url": "https://alliancegenome.org/gene/MGI:1344694#orthology", "database": "AGR" }, { "id": "FB:FBgn0046247", "url": "https://alliancegenome.org/gene/FB:FBgn0046247#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9D9G3-1", "protein_name": "Cysteine-rich hydrophobic domain-containing protein 2", "gene_name": "Chic2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLRKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD", "length": 165 }, "evidence": [ { "id": "FB:FBgn0046247", "url": "https://alliancegenome.org/gene/FB:FBgn0046247#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKJ5-1", "protein_name": "Cysteine-rich hydrophobic domain-containing protein 2", "gene_name": "CHIC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADFDEIYEEEEDEERALEEQLLKYSPDPVVVRGSGHVTVFGLSNKFESEFPSSLTGKVAPEEFKASINRVNSCLKKNLPVNVRWLLCGCLCCCCTLGCSMWPVICLSKRTRRSIEKLLEWENNRLYHKLCLHWRLSKRKCETNNMMEYVILIEFLPKTPIFRPD", "length": 165 }, "evidence": [ { "id": "FB:FBgn0046247", "url": "https://alliancegenome.org/gene/FB:FBgn0046247#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B0R125", "url": "https://www.uniprot.org/uniprotkb/B0R125" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0R125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0R125" }, { "id": "PF10256", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10256" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Golgin subfamily A member 7/ERF4", "eco_id": "ECO_0000259", "start_pos": 53, "end_pos": 142, "start_aa": "Asn", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0S522-1", "uniprot_ac": "B0S522", "uniprot_id": "B0S522_DANRE", "mass": { "chemical_mass": 52085.0, "monoisotopic_mass": 52085.0 }, "refseq": { "ac": "NP_001120874", "name": "RNA-binding protein 45", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120874" }, "gene_names": [ { "name": "rbm45", "type": "recommended", "evidence": [ { "id": "B0S522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S522" } ] }, { "name": "drb1", "type": "synonym", "evidence": [ { "id": "NP_001120874", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120874" }, { "id": "B0S522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S522" } ] }, { "name": "rbm45", "type": "synonym", "evidence": [ { "id": "NP_001120874", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120874" } ] }, { "name": "si:ch211-222f23.2", "type": "synonym", "evidence": [ { "id": "NP_001120874", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120874" }, { "id": "B0S522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S522" } ] } ], "protein_names": [ { "name": "RNA-binding protein 45", "type": "synonym", "evidence": [ { "id": "NP_001120874", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120874" }, { "id": "B0S522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S522/entry#names_and_taxonomy" } ] }, { "name": "developmentally regulated RNA-binding protein 1", "type": "synonym", "evidence": [ { "id": "NP_001120874", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120874" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588717.7432007.1, SRR32588718.19782186.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000009.1. On Jul 31, 2008 this sequence version replaced XP_696948.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001120874", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120874" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S522", "url": "https://www.uniprot.org/uniprotkb/B0S522" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rbm45", "url": "https://www.uniprot.org/uniprotkb/B0S522", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070122-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070122-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000063731", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000063731", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12366", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12366", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12367", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12367", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12368", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12368", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12369", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12369", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "568524", "url": "https://www.ncbi.nlm.nih.gov/gene/568524", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034203", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034203", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034208", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034208", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052462", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052462", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:568524", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568524", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MIPKTYT", "url": "https://omabrowser.org/oma/group/MIPKTYT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S522", "url": "https://www.orthodb.org/?gene=B0S522", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48027", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48027", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001120874", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001120874", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S522", "url": "https://www.uniprot.org/uniprotkb/B0S522", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S522-1", "url": "https://www.uniprot.org/uniprotkb/B0S522-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070122-4", "url": "https://zfin.org/ZDB-GENE-070122-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDDSNRPSSYLDEPPNSRLFLVTSKSITEDTIRESFASFGEIQDIWVVKDKQTKESKGVAFIKFAKSSQACTAMEEMHGRCLAEGTKPIKVFIAQSRSSGSHRDVEDEELTRIFVMIPKTFTEDDLKETFKVYGDIEYAIIIRNKTTGDSKGLGYVRFHKPSQAAKAVENCDKTFRAIIAEPRTKNSSADNDYFSNPRTTEHSTSELGSSSYAFAQESSSYSAAESYSSDIITRCLMVSSRVSVSQEQIYSLFDLIPGLDYCEIQRDQYGFSKGQVVVRYSNLGSAVYAKEKLNGFEYPPGNRLSVSFVDDGEDRTSPVGKMAMQLVAAQMMSMVWNGPSGSQLMKTSAGYTAPPVPQKARLQTDANLPAPKKLLALDSVVKERLFVIFNPSPLPVEVLEDVFCRFGSLIEVYLVPGRNVGYIKYADRRSAHDAIDTMHGKVVNGVKMKVMLADPPKEESHKRQRTY", "length": 467, "header": "tr|B0S522-1|B0S522_DANRE Isoform 1 of RNA-binding protein 45 OS=Danio rerio OX=7955 GN=rbm45 PE=1 SV=1 CANONICAL=B0S522-1" }, "isoforms": [ { "isoform_ac": "B0S522-1", "url": "https://www.uniprot.org/uniprotkb/B0S522/entry#B0S522-1", "sequence": { "sequence": "MDDSNRPSSYLDEPPNSRLFLVTSKSITEDTIRESFASFGEIQDIWVVKDKQTKESKGVAFIKFAKSSQACTAMEEMHGRCLAEGTKPIKVFIAQSRSSGSHRDVEDEELTRIFVMIPKTFTEDDLKETFKVYGDIEYAIIIRNKTTGDSKGLGYVRFHKPSQAAKAVENCDKTFRAIIAEPRTKNSSADNDYFSNPRTTEHSTSELGSSSYAFAQESSSYSAAESYSSDIITRCLMVSSRVSVSQEQIYSLFDLIPGLDYCEIQRDQYGFSKGQVVVRYSNLGSAVYAKEKLNGFEYPPGNRLSVSFVDDGEDRTSPVGKMAMQLVAAQMMSMVWNGPSGSQLMKTSAGYTAPPVPQKARLQTDANLPAPKKLLALDSVVKERLFVIFNPSPLPVEVLEDVFCRFGSLIEVYLVPGRNVGYIKYADRRSAHDAIDTMHGKVVNGVKMKVMLADPPKEESHKRQRTY", "length": 467, "header": "tr|B0S522-1|B0S522_DANRE Isoform 1 of RNA-binding protein 45 OS=Danio rerio OX=7955 GN=rbm45 PE=1 SV=1 CANONICAL=B0S522-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Phylogenetic and chromosomal analyses of multiple gene families syntenic with vertebrate Hox clusters.", "journal": "BMC Evol. Biol.", "date": "2008", "authors": "Sundstr\u00f6m G\u00f6rel, Larsson Tomas A, Larhammar Dan", "evidence": [ { "database": "UniProtKB", "id": "B0S522", "url": "https://www.uniprot.org/uniprotkb/B0S522" } ], "reference": [ { "type": "PubMed", "id": "18803835", "url": "https://glygen.org/publication/PubMed/18803835" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B0S522", "url": "https://www.uniprot.org/uniprotkb/B0S522" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:568524", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568524", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0ZY00-1", "protein_name": "RNA binding motif protein 45", "gene_name": "RBM45", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLSPRRKEAGGSSSPGPEQSQRSTTAREPSGSSAMEESSGFRLSAECLDEPPNSRVFVVLGKDAGEALIRERFAPFGDIQNIWLLRDKRTNESRGIAFIKFARSSQACRAMEEMHGRSLVPDTKPIKVFIAQSRASGSHRDVEDEELTRIFVMIPKTYTEEDLREKFKMYGDIEYCSIIKNKTTGESKGLGYVRYLKPSQAARAIEECDRSYRAILAEPKNKSSESFEHEYYSNNARQEPRGNVFPFCAQPEFCSFEKNETRIQESVSKRLSVVSRLPFIQEQLFALFDLVPGLEYCDVQRDPHTNNGYAVIQYSTAASAIYAKYKLHGFEYPPGNRLTVIFLEDGNDSSDLIRKMATQLVTAHMTSVLRNNNAVVQPYRTPPQAFGGASGSPLLQPQTDAMLPPPKKKMPPDTTVKERLFVLFHPHPLPVTILEDVFCRFGNLIKVYLVAGKNVAYAKFADRASASEAITALHGKIVNGVRLKVRLADSPTEESNKRQRTY", "length": 502 }, "evidence": [ { "id": "B0S522", "url": "https://omabrowser.org/oma/group/B0S522/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7G456-1", "protein_name": "RNA-binding protein 45", "gene_name": "Rbm45", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEDSSSSAGSGGFRPGVDSLDEPPNSRIFLVISKYTSESVLRERFSPFGDIQDIWVVRDKHTKESKGVAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVLHWGAYVRVCEVFIAQSRSSGSHRDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRALLAEPKNKVPESPEQDYYSSMRQEALGHEPRVNLFPFVGEQQSEFSSFDKSDSRSQEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAVYAKYKLHGFQYPPGNRIGVSFLDDGSNSADLIRKMATQMVASQLASMVWSNPSQQQQFLQFGGSSGSQLPQIQTDVVLPSCKKKAPPETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVSGKNVGYVKYADRMSANDAISTLHGKILNGVRLKVMLADSPREEPKKRQRTY", "length": 489 }, "evidence": [ { "id": "B0S522", "url": "https://omabrowser.org/oma/group/B0S522/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8BHN5-1", "protein_name": "RNA-binding protein 45", "gene_name": "Rbm45", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDDAGGLGGSGGFRPGVDSLDEPPNSRIFLVISKHTSELVLRERFSPFGDIQDIWVVRDKHTKESKGVAFVKFARSSQACRAMEEMHGQCLGPSDTKPIKVFIAQSRSSGSHRDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRALLAEPKNKVSGSPEQDDYSSGRQEALGQEPRANLFPFVGEQQSEFSTFDKNDSRGQEAVSKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVPRDPYSNYGHGVVQYFNVASAIYAKYKLHGFQYPPGNRIVVSFLDDGSNMTELIRKMATQMVAAQLASMVWSTTSQQQFLQYGGNAASQAPQIQTDVVLPSCKKKAPPETPVKERLFVVFNPHPLPLDVLEDIFCRFGNLIEVYLVSGKNVGYVKYADRKSANEAITTLHGKILNGVRLKVMLADSPREESKKRQRTY", "length": 476 }, "evidence": [ { "id": "RGD:628862", "url": "https://alliancegenome.org/gene/RGD:628862#orthology", "database": "AGR" }, { "id": "MGI:2387367", "url": "https://alliancegenome.org/gene/MGI:2387367#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070122-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070122-4#orthology", "database": "AGR" }, { "id": "HGNC:24468", "url": "https://alliancegenome.org/gene/HGNC:24468#orthology", "database": "AGR" }, { "id": "FB:FBgn0035526", "url": "https://alliancegenome.org/gene/FB:FBgn0035526#orthology", "database": "AGR" }, { "id": "B0S522", "url": "https://omabrowser.org/oma/group/B0S522/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CFD1-1", "protein_name": "RNA-binding protein 45", "gene_name": "Rbm45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDDAGSSGGSGGFRPGVDSLDEPPNSRIFLVISKYTSESVLREHFSPFGDIQDIWVVRDKHTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSVIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRALLAEPKNKVLESPEQDYYSSVRQETLGHEPRGNLFPFVGEQQSEFSTFDKNDSRGQEAISKRLSVASRVPFTEEQLFSIFDIVPGLEYCEVHRDPYLNYGHGVVQYFNVASAVYAQYKLHGFQYPPGNRIAVSFLDDGSNSADLIRKMATQMVAAQLASTVWSNPSHQQFLQFGGSAGSQVPQIQTDVVLPSCRKKAPPETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVSGKNVGYVKYADRMSANDAITTLHGKILNGVRLKVMLADSPREVSKKRQRTY", "length": 476 }, "evidence": [ { "id": "RGD:628862", "url": "https://alliancegenome.org/gene/RGD:628862#orthology", "database": "AGR" }, { "id": "MGI:2387367", "url": "https://alliancegenome.org/gene/MGI:2387367#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070122-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070122-4#orthology", "database": "AGR" }, { "id": "HGNC:24468", "url": "https://alliancegenome.org/gene/HGNC:24468#orthology", "database": "AGR" }, { "id": "FB:FBgn0035526", "url": "https://alliancegenome.org/gene/FB:FBgn0035526#orthology", "database": "AGR" }, { "id": "B0S522", "url": "https://omabrowser.org/oma/group/B0S522/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IUH3-1", "protein_name": "RNA-binding protein 45", "gene_name": "RBM45", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDEAGSSASGGGFRPGVDSLDEPPNSRIFLVISKYTPESVLRERFSPFGDIQDIWVVRDKHTKESKGIAFVKFARSSQACRAMEEMHGQCLGPNDTKPIKVFIAQSRSSGSHRDVEDEELTRIFVMIPKSYTEEDLREKFKVYGDIEYCSIIKNKVTGESKGLGYVRYLKPSQAAQAIENCDRSFRAILAEPKNKASESSEQDYYSNMRQEALGHEPRVNMFPFVGEQQSEFSSFDKNDSRGQEAISKRLSVVSRVPFTEEQLFSIFDIVPGLEYCEVQRDPYSNYGHGVVQYFNVASAIYAKYKLHGFQYPPGNRIGVSFIDDGSNATDLLRKMATQMVAAQLASMVWNNPSQQQFMQFGGSSGSQLPQIQTDVVLPSCKKKAPAETPVKERLFIVFNPHPLPLDVLEDIFCRFGNLIEVYLVSGKNVGYAKYADRISANDAIATLHGKILNGVRLKVMLADSPREESNKRQRTY", "length": 476 }, "evidence": [ { "id": "RGD:628862", "url": "https://alliancegenome.org/gene/RGD:628862#orthology", "database": "AGR" }, { "id": "MGI:2387367", "url": "https://alliancegenome.org/gene/MGI:2387367#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070122-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070122-4#orthology", "database": "AGR" }, { "id": "HGNC:24468", "url": "https://alliancegenome.org/gene/HGNC:24468#orthology", "database": "AGR" }, { "id": "FB:FBgn0035526", "url": "https://alliancegenome.org/gene/FB:FBgn0035526#orthology", "database": "AGR" }, { "id": "B0S522", "url": "https://omabrowser.org/oma/group/B0S522/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VZE4-1", "protein_name": "RRM domain-containing protein", "gene_name": "cg1316", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDYRSQSRSGGGRGGQEYSNDDDPPMSRLFIICNKAHTEEDFREAFSPYGEIEDIWVVKDKHTQENKGIAYVKFSKTSDAAKAQEEMNGKTIGKMDRTLKVLVAANRNQGSNKSENEQEKYVRLFIVIPKTATEEDIREEFSQWGDVESVTIVKEKNNGNPKGFGYVRFTKFYYAAVAFENCSAKYKAVFAEPKGSTRTQRDQYGRPSEDNPLYSSSGRGNSNFNGGGSSSGGGGSNSYNNDWNVSQNNDMAAFLRMQNVPVAQPSCLEVNVSNCVNQDQLWRLFDIIPGLDYCQIMREHGPRTNEALVVYDNPEAAIYAKDKLHGLEYPMGERIIVKVNGMSSARMDTSFIDKRTKKDAICNVPLPPTQPLASPDDQVAQRLFIVLSANLPHSILKNIFSCWSGLIDVYLLPNKNCGYVKYAEVESAQLAIRTLNGAEICGTKIKVMEAEERSGSDGDDGGRKRLRRN", "length": 470 }, "evidence": [ { "id": "RGD:628862", "url": "https://alliancegenome.org/gene/RGD:628862#orthology", "database": "AGR" }, { "id": "MGI:2387367", "url": "https://alliancegenome.org/gene/MGI:2387367#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070122-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070122-4#orthology", "database": "AGR" }, { "id": "HGNC:24468", "url": "https://alliancegenome.org/gene/HGNC:24468#orthology", "database": "AGR" }, { "id": "FB:FBgn0035526", "url": "https://alliancegenome.org/gene/FB:FBgn0035526#orthology", "database": "AGR" }, { "id": "B0S522", "url": "https://omabrowser.org/oma/group/B0S522/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "B0S522", "url": "https://www.uniprot.org/uniprotkb/B0S522" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0S522", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S522" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 96, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], 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Transcript exon combination :: CB356059.1, SRR26395013.20986.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000009.1 and EH442214.1. On Feb 23, 2016 this sequence version replaced NP_001003476.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001003476", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001003476" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S5G4", "url": "https://www.uniprot.org/uniprotkb/B0S5G4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dnajc15", "url": "https://www.uniprot.org/uniprotkb/B0S5G4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040801-216", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040801-216", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000038309", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000038309", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06257", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06257", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "445082", "url": "https://www.ncbi.nlm.nih.gov/gene/445082", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001623", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001623", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036869", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036869", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060698", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060698", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:445082", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:445082", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MRYAEYT", "url": "https://omabrowser.org/oma/group/MRYAEYT/", "database": 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"https://www.uniprot.org/uniprotkb/A0AC58GDW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S5G4", "url": "https://www.uniprot.org/uniprotkb/B0S5G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S5G4-1", "url": "https://www.uniprot.org/uniprotkb/B0S5G4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040801-216", "url": "https://zfin.org/ZDB-GENE-040801-216", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASSSGVTLDGDLMRYAEYTPKSNMKSETDIDRRLGGALMAVGLGVAAAGFAGRYAFHLWRPLGQVITETAKKFPSSSFSAYYKGGFEQKMTRREASLILGISPTSTKTKVREAHRRIMVLNHPDKGGSPYLAAKINEAKDLLDSGPRR", "length": 149, "header": "tr|B0S5G4-1|B0S5G4_DANRE Isoform 1 of DnaJ homolog subfamily C member 15 OS=Danio rerio OX=7955 GN=dnajc15 PE=1 SV=1 CANONICAL=B0S5G4-1" }, "isoforms": [ { "isoform_ac": "A0AC58GDW0-1", "url": "https://www.uniprot.org/uniprotkb/B0S5G4/entry#A0AC58GDW0-1", "sequence": { "sequence": "MASSSGVTLDGDLMRYAEYTPKSNMKSETDIDRRLGGALMAVGLGVAAAGFAGRYAFHLWRPLGQVITEAAKKFPSSSFSAYYKGGFEQKMTRREASLILGISPTSTKTKVREAHRRIMVLNHPDKEHHLGSSTVPDGPTRKGSQTVAE", "length": 149, "header": "tr|A0AC58GDW0-1|A0AC58GDW0_DANRE Computationally mapped isoform of DnaJ homolog subfamily C member 15 isoform X1 OS=Danio rerio OX=7955 GN=dnajc15 PE=1 SV=1 CANONICAL=B0S5G4-1" }, "locus": {} }, { "isoform_ac": "B0S5G4-1", "url": "https://www.uniprot.org/uniprotkb/B0S5G4/entry#B0S5G4-1", "sequence": { "sequence": "MASSSGVTLDGDLMRYAEYTPKSNMKSETDIDRRLGGALMAVGLGVAAAGFAGRYAFHLWRPLGQVITETAKKFPSSSFSAYYKGGFEQKMTRREASLILGISPTSTKTKVREAHRRIMVLNHPDKGGSPYLAAKINEAKDLLDSGPRR", "length": 149, "header": "tr|B0S5G4-1|B0S5G4_DANRE Isoform 1 of DnaJ homolog subfamily C member 15 OS=Danio rerio OX=7955 GN=dnajc15 PE=1 SV=1 CANONICAL=B0S5G4-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 105, "start_aa": "Thr", "end_pos": 105, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr105", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.", "journal": "Proc. 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Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "B0S5G4", "url": "https://www.uniprot.org/uniprotkb/B0S5G4" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0S5G4", "url": "https://www.uniprot.org/uniprotkb/B0S5G4" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:445082", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:445082", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6GJ68-1", "protein_name": "DnaJ heat shock protein family (Hsp40) member C15", "gene_name": "Dnajc15", "tax_id": 10116, 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"https://www.ncbi.nlm.nih.gov/protein/NP_001116735" }, "gene_names": [ { "name": "si:ch211-229n2.6", "type": "recommended", "evidence": [ { "id": "B0S5H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S5H8" } ] }, { "name": "plaat1l.1", "type": "synonym", "evidence": [ { "id": "NP_001116735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116735" } ] }, { "name": "plaat1l1", "type": "synonym", "evidence": [ { "id": "NP_001116735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116735" } ] }, { "name": "si:ch211-229n2.6", "type": "synonym", "evidence": [ { "id": "NP_001116735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116735" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC561916", "type": "synonym", "evidence": [ { "id": "B0S5H8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S5H8/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC561916", "type": "synonym", "evidence": [ { "id": "NP_001116735", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116735" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CK027746.1, SRR32588729.13421689.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000008.1. On Apr 11, 2008 this sequence version replaced XP_690411.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001116735", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116735" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S5H8", "url": "https://www.uniprot.org/uniprotkb/B0S5H8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-229n2.6", "url": "https://www.uniprot.org/uniprotkb/B0S5H8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081105-166", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-166", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092122", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092122", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "561916", "url": "https://www.ncbi.nlm.nih.gov/gene/561916", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007053", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007053", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561916", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561916", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QTIFPAC", "url": "https://omabrowser.org/oma/group/QTIFPAC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S5H8", "url": "https://www.orthodb.org/?gene=B0S5H8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13943", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13943", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13943:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13943:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001116735", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116735", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S5H8", "url": "https://www.uniprot.org/uniprotkb/B0S5H8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S5H8-1", "url": "https://www.uniprot.org/uniprotkb/B0S5H8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081105-166", "url": "https://zfin.org/ZDB-GENE-081105-166", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDYQEQVENVISSAQLGDLIEFAYPIGYSHWGVYEGDGYVVHFAVADESKVMSKFRGFLQTIFPACGDLLLGETKIRRQLLSEVNVPKGAIVSVSNSQHDLQPSPPEEIRGRLNGLVNKEFTYKLLTFNCEHFATFVRSGKAVCNQIPGKEKDNECVEATKLFSLFVPAC", "length": 170, "header": "tr|B0S5H8-1|B0S5H8_DANRE Isoform 1 of Uncharacterized protein LOC561916 OS=Danio rerio OX=7955 GN=si:ch211-229n2.6 PE=3 SV=1 CANONICAL=B0S5H8-1" }, "isoforms": [ { "isoform_ac": "B0S5H8-1", "url": "https://www.uniprot.org/uniprotkb/B0S5H8/entry#B0S5H8-1", "sequence": { "sequence": "MDYQEQVENVISSAQLGDLIEFAYPIGYSHWGVYEGDGYVVHFAVADESKVMSKFRGFLQTIFPACGDLLLGETKIRRQLLSEVNVPKGAIVSVSNSQHDLQPSPPEEIRGRLNGLVNKEFTYKLLTFNCEHFATFVRSGKAVCNQIPGKEKDNECVEATKLFSLFVPAC", "length": 170, "header": "tr|B0S5H8-1|B0S5H8_DANRE Isoform 1 of Uncharacterized protein LOC561916 OS=Danio rerio OX=7955 GN=si:ch211-229n2.6 PE=3 SV=1 CANONICAL=B0S5H8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.", "journal": "J. 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"id": "XP_017213244", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213244" } ] } ], "protein_names": [ { "name": "L-rhamnose-binding lectin CSL2", "type": "synonym", "evidence": [ { "id": "XP_017213244", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213244" }, { "id": "B0S5U6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S5U6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213244", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213244" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S5U6", "url": "https://www.uniprot.org/uniprotkb/B0S5U6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-145c1.1", "url": "https://www.uniprot.org/uniprotkb/B0S5U6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-81", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-81", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000042063", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000042063", "database": "Bgee", "categories": [ "Gene 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"NP_001116762", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116762" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01037843.1, EH434211.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505375, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000004.1. On Apr 11, 2008 this sequence version replaced XP_696802.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001116762", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116762" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S5X1", "url": "https://www.uniprot.org/uniprotkb/B0S5X1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkeyp-38g8.5", "url": "https://www.uniprot.org/uniprotkb/B0S5X1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-62", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-62", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000056954", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000056954", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "568385", "url": "https://www.ncbi.nlm.nih.gov/gene/568385", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR044822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:568385", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568385", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RNTSMWA", "url": "https://omabrowser.org/oma/group/RNTSMWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S5X1", "url": "https://www.orthodb.org/?gene=B0S5X1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR38709", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38709", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR38709:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR38709:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13837", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13837", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001116762", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116762", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S5X1", "url": "https://www.uniprot.org/uniprotkb/B0S5X1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S5X1-1", "url": "https://www.uniprot.org/uniprotkb/B0S5X1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-62", "url": "https://zfin.org/ZDB-GENE-081104-62", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSALDDSKTTDTSMDHELYTVQSPSDDIKDGPEHSEFIYKMSNEEFVRFVKLRVTNDALFTGKRNSSTLAYRAILKELGLQREISASQARRKWENLKMKYKEMKNPPPGVSVNPTNWPWFSLMDDAMEGRLVGSDVTLDTSSVGDDSEYRPNNSTRRRSKRAREPDRSEIELFVEEDDIMSEEMGRDRGDLDRDRDEMEHERAILESDKAAIEYERMVLEREKMVLDRERAGVERELAALDRDRASLEREKAAVERDRASVEYIRAQLEKDRAILDRERAKLERERAILDQQRGIEKSEQTVNLNDNSEGTDTSIPLVMEPASLERRQKFLNLFEKLIENF", "length": 342, "header": "tr|B0S5X1-1|B0S5X1_DANRE Isoform 1 of Uncharacterized protein LOC568385 OS=Danio rerio OX=7955 GN=si:dkeyp-38g8.5 PE=4 SV=1 CANONICAL=B0S5X1-1" }, "isoforms": [ { "isoform_ac": "B0S5X1-1", "url": "https://www.uniprot.org/uniprotkb/B0S5X1/entry#B0S5X1-1", "sequence": { "sequence": "MSSALDDSKTTDTSMDHELYTVQSPSDDIKDGPEHSEFIYKMSNEEFVRFVKLRVTNDALFTGKRNSSTLAYRAILKELGLQREISASQARRKWENLKMKYKEMKNPPPGVSVNPTNWPWFSLMDDAMEGRLVGSDVTLDTSSVGDDSEYRPNNSTRRRSKRAREPDRSEIELFVEEDDIMSEEMGRDRGDLDRDRDEMEHERAILESDKAAIEYERMVLEREKMVLDRERAGVERELAALDRDRASLEREKAAVERDRASVEYIRAQLEKDRAILDRERAKLERERAILDQQRGIEKSEQTVNLNDNSEGTDTSIPLVMEPASLERRQKFLNLFEKLIENF", "length": 342, "header": "tr|B0S5X1-1|B0S5X1_DANRE Isoform 1 of Uncharacterized protein LOC568385 OS=Danio rerio OX=7955 GN=si:dkeyp-38g8.5 PE=4 SV=1 CANONICAL=B0S5X1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0S5X1", "url": "https://www.uniprot.org/uniprotkb/B0S5X1" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B0S5X1", "url": "https://www.uniprot.org/uniprotkb/B0S5X1" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:568385", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568385", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "B0S5X1", "url": "https://www.uniprot.org/uniprotkb/B0S5X1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 153, "end_pos": 155, "annotation": "n_glycosylation_sequon" }, { "start_pos": 154, "end_pos": 156, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0S5X1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S5X1" }, { "id": "PF13837", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb/SANT-like DNA-binding", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 126, "start_aa": "Asn", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 153, "end_pos": 155 }, { "start_pos": 154, "end_pos": 156 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0S636-1", "uniprot_ac": "B0S636", "uniprot_id": "B0S636_DANRE", "mass": { "chemical_mass": 32309.0, "monoisotopic_mass": 32309.0 }, "refseq": { "ac": "XP_001344534", "name": "myeloid-associated differentiation marker homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344534" }, "gene_names": [ { "name": "myadma", "type": "recommended", "evidence": [ { "id": "B0S636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S636" } ] }, { "name": "myadma", "type": "synonym", "evidence": [ { "id": "XP_001344534", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344534" } ] } ], "protein_names": [ { "name": "Myeloid-associated differentiation marker homolog", "type": "synonym", "evidence": [ { "id": "B0S636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S636/entry#names_and_taxonomy" } ] }, { "name": "myeloid-associated differentiation marker homolog", "type": "synonym", "evidence": [ { "id": "XP_001344534", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344534" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_001344534.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001344534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344534" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S636", "url": "https://www.uniprot.org/uniprotkb/B0S636" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "myadma", "url": "https://www.uniprot.org/uniprotkb/B0S636", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-664", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-664", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000086815", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000086815", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100005501", "url": "https://www.ncbi.nlm.nih.gov/gene/100005501", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047123", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047123", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100005501", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005501", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEPALEW", "url": "https://omabrowser.org/oma/group/QEPALEW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S636", "url": "https://www.orthodb.org/?gene=B0S636", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17068", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17068", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17068:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17068:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01284", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01284", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001344534", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344534", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S636", "url": "https://www.uniprot.org/uniprotkb/B0S636", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S636-1", "url": "https://www.uniprot.org/uniprotkb/B0S636-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-664", "url": "https://zfin.org/ZDB-GENE-070912-664", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPVVVFRPTQLMWARLAALVFTCVAFSVASHGGSLNGSIGDWSIFCWAFSFAGTLVVLLVELLGLQSRSPVSWNNFPITFACYAALLCLTASIIFPLYFLKGVTTYNEIRDHRIAASVFSCLATIAYFVEVSLARARPGEVAGYMATVPGLLKVCETFVASVIFVFISDPISYDSHSALKWCLAVYCICFVISAAIVVLCIGECTGCLPFPFARFLSAYALLAVLMYLTATIIWPVFKFDSRYNGQSNRPYQCQSRQGLCPWDKLVAVAVLTALNFLIYLADLAYSARLVFVTV", "length": 294, "header": "tr|B0S636-1|B0S636_DANRE Isoform 1 of Myeloid-associated differentiation marker homolog OS=Danio rerio OX=7955 GN=myadma PE=3 SV=1 CANONICAL=B0S636-1" }, "isoforms": [ { "isoform_ac": "B0S636-1", "url": "https://www.uniprot.org/uniprotkb/B0S636/entry#B0S636-1", "sequence": { "sequence": "MPVVVFRPTQLMWARLAALVFTCVAFSVASHGGSLNGSIGDWSIFCWAFSFAGTLVVLLVELLGLQSRSPVSWNNFPITFACYAALLCLTASIIFPLYFLKGVTTYNEIRDHRIAASVFSCLATIAYFVEVSLARARPGEVAGYMATVPGLLKVCETFVASVIFVFISDPISYDSHSALKWCLAVYCICFVISAAIVVLCIGECTGCLPFPFARFLSAYALLAVLMYLTATIIWPVFKFDSRYNGQSNRPYQCQSRQGLCPWDKLVAVAVLTALNFLIYLADLAYSARLVFVTV", "length": 294, "header": "tr|B0S636-1|B0S636_DANRE Isoform 1 of Myeloid-associated differentiation marker homolog OS=Danio rerio OX=7955 GN=myadma PE=3 SV=1 CANONICAL=B0S636-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100005501", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005501", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O35682-1", "protein_name": "Myeloid-associated differentiation marker", "gene_name": "Myadm", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPVTVTRTTITTTTSSSTTVGSARALTQPLGLLRLLQLISTCVAFSLVASVGAWTGPMGNWAMFTWCFCFAVTLIILIVELGGLQAHFPLSWRNFPITFACYAALFCLSSSIIYPTTYVQFLAHGRTRDHAIAATTFSCVACLAYATEVAWTRARPGEITGYMATVPGLLKVFETFVACIIFAFISEPLLYNQKPALEWCVAVYAICFILAGVTILLNLGDCTNVLPIPFPTFLSGLALLSVLFYATAIVLWPLYQFDQRYQGQPRRSMDPSCTRSISYIQPNTVCFWDRRLAVSILTGINLLAYVSDLVYSTRLVFVKV", "length": 320 }, "evidence": [ { "id": "MGI:1355332", "url": "https://alliancegenome.org/gene/MGI:1355332#orthology", "database": "AGR" }, { "id": "HGNC:7544", "url": "https://alliancegenome.org/gene/HGNC:7544#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-664", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-664#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6VBQ5-1", "protein_name": "Myeloid-associated differentiation marker", "gene_name": "Myadm", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPVTVTRTTITTTSSSSTTVGSARALTQPLGLLRLLQLVSTCVAFSLVASVGAWTGPMGNWAMFTWCFCFAVTLIILIEELGGFQARFPLSWRNFPITFACYAALFCLSSSIIYPTTYVQFLPHGRSRDHAIAATTFSCVACLAYATEVAWTRARPGEITGYMATVPGLLKVFETFVACIIFAFISEPSLYQQRPALEWCVAVYAICFILAAVTVLLNLGDCTNMLPIPFPTFLSGLALLSVLLYATAIVLWPLYQFDQRYNSQPRRSMDPSCSRSYVQPNEVCNWDRRLAVSILTGINLLAYVSDLVYSTRLVFVKV", "length": 318 }, "evidence": [ { "id": "MGI:1355332", "url": "https://alliancegenome.org/gene/MGI:1355332#orthology", "database": "AGR" }, { "id": "HGNC:7544", "url": "https://alliancegenome.org/gene/HGNC:7544#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96S97-1", "protein_name": "Myeloid-associated differentiation marker", "gene_name": "MYADM", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPVTVTRTTITTTTTSSSGLGSPMIVGSPRALTQPLGLLRLLQLVSTCVAFSLVASVGAWTGSMGNWSMFTWCFCFSVTLIILIVELCGLQARFPLSWRNFPITFACYAALFCLSASIIYPTTYVQFLSHGRSRDHAIAATFFSCIACVAYATEVAWTRARPGEITGYMATVPGLLKVLETFVACIIFAFISDPNLYQHQPALEWCVAVYAICFILAAIAILLNLGECTNVLPIPFPSFLSGLALLSVLLYATALVLWPLYQFDEKYGGQPRRSRDVSCSRSHAYYVCAWDRRLAVAILTAINLLAYVADLVHSAHLVFVKV", "length": 322 }, "evidence": [ { "id": "MGI:1355332", "url": "https://alliancegenome.org/gene/MGI:1355332#orthology", "database": "AGR" }, { "id": "HGNC:7544", "url": "https://alliancegenome.org/gene/HGNC:7544#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-664", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-664#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "X1WCE8-1", "protein_name": "Myeloid-associated differentiation marker homolog", "gene_name": "myadmb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVVLRSSPLLWTRVAAMVFACVAFSVSMYGSRLTHGTGDWCVFCWSFSFVGTLLIILVEMFGLQTRAPVSWKNFPITFACYASLLCLSASIIFPLYFLKGFAGRTEMINCRIVSTVFSCLATIAYLSEVSLSKARPGEVSGYMATAPGLLKVCETFIACIIFVFISEPESYKQNAATQWCLAVYCICFILSAGIIVMCVGECTGCLPFSFARFLSTYALLAVSMYLSATIIWPIYKFDNKHGGQSHRPNICGSSIGLCPWDKLVAITVLSSLNFILYLADLIYSARLVFVNA", "length": 293 }, "evidence": [ { "id": "MGI:1355332", "url": "https://alliancegenome.org/gene/MGI:1355332#orthology", "database": "AGR" }, { "id": "HGNC:7544", "url": "https://alliancegenome.org/gene/HGNC:7544#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B0S636", "url": "https://www.uniprot.org/uniprotkb/B0S636" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 36, "end_pos": 38, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0S636", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S636" }, { "id": "PS51225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MARVEL", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 139, "start_aa": "Phe", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 36, "end_pos": 38 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0S661-1", "uniprot_ac": "B0S661", "uniprot_id": "B0S661_DANRE", "mass": { "chemical_mass": 28498.0, "monoisotopic_mass": 28498.0 }, "refseq": { "ac": "NP_001002545", "name": "tubulin polyglutamylase complex subunit 1 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002545" }, "gene_names": [ { "name": "tpgs1", "type": "recommended", "evidence": [ { "id": "B0S661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S661" } ] }, { "name": "tpgs1", "type": "synonym", "evidence": [ { "id": "NP_001002545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002545" } ] }, { "name": "wu:fk81b05", "type": "synonym", "evidence": [ { "id": "NP_001002545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002545" }, { "id": "B0S661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S661" } ] }, { "name": "zgc:92789", "type": "synonym", "evidence": [ { "id": "NP_001002545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002545" }, { "id": "B0S661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S661" } ] } ], "protein_names": [ { "name": "Tubulin polyglutamylase complex subunit 1", "type": "synonym", "evidence": [ { "id": "B0S661", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S661/entry#names_and_taxonomy" } ] }, { "name": "tubulin polyglutamylase complex subunit 1 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001002545", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002545" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC076263.1, EH456309.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Jun 18, 2015 this sequence version replaced NP_001002545.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001002545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002545" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S661", "url": "https://www.uniprot.org/uniprotkb/B0S661" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tpgs1", "url": "https://www.uniprot.org/uniprotkb/B0S661", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040718-280", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-280", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000027547", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000027547", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "436818", "url": "https://www.ncbi.nlm.nih.gov/gene/436818", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:436818", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:436818", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FSDYIRQ", "url": "https://omabrowser.org/oma/group/FSDYIRQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S661", "url": "https://www.orthodb.org/?gene=B0S661", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31932:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31932:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24480", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24480", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001002545", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001002545", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58GQ65", "url": "https://www.uniprot.org/uniprotkb/A0AC58GQ65", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GQ65-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GQ65-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S661", "url": "https://www.uniprot.org/uniprotkb/B0S661", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S661-1", "url": "https://www.uniprot.org/uniprotkb/B0S661-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040718-280", "url": "https://zfin.org/ZDB-GENE-040718-280", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSEKRRAGVLVSGSSSSSGCEADQEFVSRSGVSALLAGALLRLLDCRSGDPLGFLAEHFAHLSAEAEEGGAEQRSLSRALWMLSLQHHSQRSAFNSSVRVSYDLLSQCGAGVGGVGGRLYTETLQSLCSEGGLSASTSAPLLRRLQCREHETVPFELYRQAVLTCSVFADYIRKSQCLYAAVASAPDRPAQRTLCCAVLETLKEALETADGPDTARYLEASAKISPAKVAQAMAEAHSQTRDGETMDAQEFEDAAAALFIARVRTVT", "length": 267, "header": "tr|B0S661-1|B0S661_DANRE Isoform 1 of Tubulin polyglutamylase complex subunit 1 OS=Danio rerio OX=7955 GN=tpgs1 PE=4 SV=1 CANONICAL=B0S661-1" }, "isoforms": [ { "isoform_ac": "A0AC58GQ65-1", "url": "https://www.uniprot.org/uniprotkb/B0S661/entry#A0AC58GQ65-1", "sequence": { "sequence": "MSEKRRAGVLVSGSSSSSGCEADQEFVSRSGVSALLAGALLRLLDCRSGDPLGFLAEHFAHLSAEAEEGGAEQRSLSRALWMLSLQHHSQRLVLRSLRLKWRRQWQRLIRRRGTEKQWMRRSLRMRPRRSSSHGFEPSHDLLSETWRSSD", "length": 150, "header": "tr|A0AC58GQ65-1|A0AC58GQ65_DANRE Computationally mapped isoform of Tubulin polyglutamylase complex subunit 1 isoform X1 OS=Danio rerio OX=7955 GN=tpgs1 PE=4 SV=1 CANONICAL=B0S661-1" }, "locus": {} }, { "isoform_ac": "B0S661-1", "url": "https://www.uniprot.org/uniprotkb/B0S661/entry#B0S661-1", "sequence": { "sequence": "MSEKRRAGVLVSGSSSSSGCEADQEFVSRSGVSALLAGALLRLLDCRSGDPLGFLAEHFAHLSAEAEEGGAEQRSLSRALWMLSLQHHSQRSAFNSSVRVSYDLLSQCGAGVGGVGGRLYTETLQSLCSEGGLSASTSAPLLRRLQCREHETVPFELYRQAVLTCSVFADYIRKSQCLYAAVASAPDRPAQRTLCCAVLETLKEALETADGPDTARYLEASAKISPAKVAQAMAEAHSQTRDGETMDAQEFEDAAAALFIARVRTVT", "length": 267, "header": "tr|B0S661-1|B0S661_DANRE Isoform 1 of Tubulin polyglutamylase complex subunit 1 OS=Danio rerio OX=7955 GN=tpgs1 PE=4 SV=1 CANONICAL=B0S661-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0S661", "url": "https://www.uniprot.org/uniprotkb/B0S661" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B0S661", "url": "https://www.uniprot.org/uniprotkb/B0S661" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Brain transcriptome analysis of a familial Alzheimer's disease-like mutation in the zebrafish presenilin 1 gene implies effects on energy production.", "journal": "Mol. Brain", "date": "2019", "authors": "Newman Morgan, Hin Nhi, Pederson Stephen, Lardelli Michael", "evidence": [ { "database": "UniProtKB", "id": "B0S661", "url": "https://www.uniprot.org/uniprotkb/B0S661" } ], "reference": [ { "type": "PubMed", "id": "31053140", "url": "https://glygen.org/publication/PubMed/31053140" } ] } ], "pathway": [ { "id": "dre:436818", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:436818", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1L1S0C9-1", "protein_name": "Tubulin polyglutamylase complex subunit 1", "gene_name": "TPGS1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MATYEKRRAAVTPTAAAGSGLGDEAEFLLQADVTAMVREALLKVLEARPEEPVSFLADYFERLVLSSSGAAGEAAAELSGPMQRLSRALWYVRLAHHSHRTAFNNNISTAYEVLGAGGRRRRLGVDGRLYSELLRRICQHGDAPQEVAAELLRRVQCRDHEAVPFDVFRYGVLTCFVLLEFVTKARMLYDVLDSGAGVADKSVCQAVLCTLEEALGASGLSVPVRYLEAGSRLGPDCLALAMDRALQERKLSTTMSREEFLKKATALFVAKVKPVE", "length": 276 }, "evidence": [ { "id": "B0S661", "url": "https://omabrowser.org/oma/group/B0S661/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A8C2MJH8-1", "protein_name": "Tubulin polyglutamylase complex subunit 1", "gene_name": "Tpgs1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAALPVPLPSAKMAAVEKRRLAVTPAASFADSGRTTVSQAAAAAESEEDFLRQVGVTEMLRAALLKVLETRPEEPIAFLAHYFENMGLRSPANGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRTAFNNNVSVAYECLSASGRKKKPGLDGRTYSELLKRVCRDGGAPEEVVAPLLRKIQCRDHEAVPLGIFRAGMLSCFVLLEFVARASALFQLLEDPGLAVADRRVGQAVLDTLEGALGAGDLAAAPTHYLEAGSRLGPDSLARALDRAATGRRPSAPMAREEFLEKAAALFIAKVKPVG", "length": 303 }, "evidence": [ { "id": "B0S661", "url": "https://omabrowser.org/oma/group/B0S661/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "D4A463-1", "protein_name": "Tubulin polyglutamylase complex subunit 1", "gene_name": "Tpgs1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAALPVPLPPAKMAAVEKRRPAVAPAANFPDSGRTSVSQAVAAAESEEDFLRQVGVTEMLRAALLKVLETRPEEPIAFLAHYFENMGLRSPANGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRTAFNNNVSVAYECLSASGRKKKPGLDGRTYSELLKRVCRDGGAPEEVVAPLLRKIQCRDHEAVPLGIFRTGMLSCFVLLEFVARASALFQLLEDPGLAVADRRVGQAVLDTLEGALSAGDLATAPTHYLEAGSRLGPDNLARALDRAAAGRRPSAPMAREEFLEKAAALFIAKVKPVG", "length": 303 }, "evidence": [ { "id": "MGI:106618", "url": "https://alliancegenome.org/gene/MGI:106618#orthology", "database": "AGR" }, { "id": "HGNC:25058", "url": "https://alliancegenome.org/gene/HGNC:25058#orthology", "database": "AGR" }, { "id": "B0S661", "url": "https://omabrowser.org/oma/group/B0S661/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BAL1-1", "protein_name": "Tubulin polyglutamylase complex subunit 1", "gene_name": "TPGS1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAALPVPLPSAKMAAVEKRRQAVAQATSFTDSGRPGVPRTAATAESEEDFLRQVGVTEMLRAALLKVLEARPEEPIAFLAHYFENMGLRSPANGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRTAFNNNVGVAYECLSASGRKKKPGLDGRTYSELLKRICRDGEAPEEVVAPLLRKIQCRDHEAVPLAVFRAGMLTCFVLLEFVARAGALYRLLEDPGLAMADRRLGQAVLDTLEGALQASDDTAPARYLEAGSRLGPDSLALAMDRALVARRPSAPMTREEFLEKAAALFIAKVKPVG", "length": 302 }, "evidence": [ { "id": "B0S661", "url": "https://omabrowser.org/oma/group/B0S661/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6ZTW0-1", "protein_name": "Tubulin polyglutamylase complex subunit 1", "gene_name": "TPGS1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAVEKRRQAVPPPAGFTDSGRQSVSRAAGAAESEEDFLRQVGVTEMLRAALLKVLEARPEEPIAFLAHYFENMGLRSPVNGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRAAFNNNVSVAYECLSAGGRRKRPGLDGRTYSELLRRICRDGQAPEEVVAPLLRKVQCRDHEAVPLSVFRAGTLTCFVLLEFVARAGALFQLLEDSAAAVADRRVGQAVLDTLEGALQASDAAAPARFLEAGSRLGPDSLALALDRAVGGRRPSAPMTREEFLERAAALFIAKVKPVG", "length": 290 }, "evidence": [ { "id": "MGI:106618", "url": "https://alliancegenome.org/gene/MGI:106618#orthology", "database": "AGR" }, { "id": "HGNC:25058", "url": "https://alliancegenome.org/gene/HGNC:25058#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040718-280", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040718-280#orthology", "database": "AGR" }, { "id": "B0S661", "url": "https://omabrowser.org/oma/group/B0S661/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99MS8-1", "protein_name": "Tubulin polyglutamylase complex subunit 1", "gene_name": "Tpgs1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAALPVPLPPTKMAAVEKRRPAVAPAANFPDSGRTSVSQAAAAAESEEDFLRQLGVTEMLRAALLKVLEIRPEEPIAFLAHYFENMGLRSPTNGGAGEPPGQLLLQQQRLGRALWHLRLAHHSQRTAFNNNVSVAYECLSASGRKKKPGLDGRTYSELLKRVCRDGGAPEEVVAPLLRKIQCRDHEAVPLGIFRTGMLSCFVLLEFVARAGALFQLLEDPGQAVADRRVGQAVLDTLEGALSAGDMATAPTHYLEAGSRLGPDNLARALDRAASGRRPSVPMAREEFLEKAAALFIAKVKPVG", "length": 303 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0S6B5-1", "uniprot_ac": "B0S6B5", "uniprot_id": "B0S6B5_DANRE", "mass": { "chemical_mass": 49596.0, "monoisotopic_mass": 49596.0 }, "refseq": { "ac": "NP_001070637", "name": "interferon induced protein 44c2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070637" }, "gene_names": [ { "name": "ifi44c2", "type": "recommended", "evidence": [ { "id": "B0S6B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6B5" } ] }, { "name": "ifi44c2", "type": "synonym", "evidence": [ { "id": "NP_001070637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070637" } ] }, { "name": "zgc:153654", "type": "synonym", "evidence": [ { "id": "NP_001070637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070637" }, { "id": "B0S6B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6B5" } ] } ], "protein_names": [ { "name": "Interferon induced protein 44c2", "type": "synonym", "evidence": [ { "id": "B0S6B5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6B5/entry#names_and_taxonomy" } ] }, { "name": "interferon induced protein 44c2", "type": "synonym", "evidence": [ { "id": "NP_001070637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070637" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC124414.1, GFIL01045251.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1 and CN504954.1. On or before Jun 19, 2015 this sequence version replaced XP_005171366.1, NP_001070637.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001070637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070637" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S6B5", "url": "https://www.uniprot.org/uniprotkb/B0S6B5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ifi44c2", "url": "https://www.uniprot.org/uniprotkb/B0S6B5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060929-1102", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-1102", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000060322", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000060322", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00882", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00882", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "565601", "url": "https://www.ncbi.nlm.nih.gov/gene/565601", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565601", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565601", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SLMEKPW", "url": "https://omabrowser.org/oma/group/SLMEKPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S6B5", "url": "https://www.orthodb.org/?gene=B0S6B5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14241:SF19", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14241:SF19", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001070637", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070637", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S6B5", "url": "https://www.uniprot.org/uniprotkb/B0S6B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S6B5-1", "url": "https://www.uniprot.org/uniprotkb/B0S6B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060929-1102", "url": "https://zfin.org/ZDB-GENE-060929-1102", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSTIISSLTKKQKKKLCSLLNNAKLSLLYKASVHGYSTSTFNQKCDKQGPTVVVAYNKSGYVFGAFTSKDYGQTGQNIVDDKAFLFSFNDKELEEDPLRVISGNPKFAFTDNGPNFDSLIFLYNSTATVNSNPGTYQFDPQRMHGNDLILTECEVYRVEGCGGLMEKPWRNVHWDSEKKKALLSSISSWKPSVSSIKQARILLLGPIGAGKSSFFNSINSVFKGYVSMQANTGTAETSLTTQFRTYYTKPGSSVSHVPFTLCDTMGLEEGLNCGLDVDDFASILKGHIQDRYQFNPSMPIQPDSPYFVKSPGLKDKIHCVVYVIDACKVNLLSDKIIEKFAVFRKKTNQLGIPQLVLLTKVDEACPLVAEDLKNVYRSHYINQMMQEVSTQLGVSLSAVVPVKNYCQELEIDPQTDILLLNGLIQMLRAAEGFFDDCYNPEEKSE", "length": 445, "header": "tr|B0S6B5-1|B0S6B5_DANRE Isoform 1 of Interferon induced protein 44c2 OS=Danio rerio OX=7955 GN=ifi44c2 PE=3 SV=1 CANONICAL=B0S6B5-1" }, "isoforms": [ { "isoform_ac": "B0S6B5-1", "url": "https://www.uniprot.org/uniprotkb/B0S6B5/entry#B0S6B5-1", "sequence": { "sequence": "MSTIISSLTKKQKKKLCSLLNNAKLSLLYKASVHGYSTSTFNQKCDKQGPTVVVAYNKSGYVFGAFTSKDYGQTGQNIVDDKAFLFSFNDKELEEDPLRVISGNPKFAFTDNGPNFDSLIFLYNSTATVNSNPGTYQFDPQRMHGNDLILTECEVYRVEGCGGLMEKPWRNVHWDSEKKKALLSSISSWKPSVSSIKQARILLLGPIGAGKSSFFNSINSVFKGYVSMQANTGTAETSLTTQFRTYYTKPGSSVSHVPFTLCDTMGLEEGLNCGLDVDDFASILKGHIQDRYQFNPSMPIQPDSPYFVKSPGLKDKIHCVVYVIDACKVNLLSDKIIEKFAVFRKKTNQLGIPQLVLLTKVDEACPLVAEDLKNVYRSHYINQMMQEVSTQLGVSLSAVVPVKNYCQELEIDPQTDILLLNGLIQMLRAAEGFFDDCYNPEEKSE", "length": 445, "header": "tr|B0S6B5-1|B0S6B5_DANRE Isoform 1 of Interferon induced protein 44c2 OS=Danio rerio OX=7955 GN=ifi44c2 PE=3 SV=1 CANONICAL=B0S6B5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.", "journal": "J. Immunol.", "date": "2014", "authors": "Briolat Val\u00e9rie, Jouneau Luc, Carvalho Ralph, Palha Nuno, Langevin Christelle, Herbomel Philippe, Schwartz Olivier, Spaink Herman P, Levraud Jean-Pierre, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "B0S6B5", "url": "https://www.uniprot.org/uniprotkb/B0S6B5" } ], "reference": [ { "type": "PubMed", "id": "24683187", "url": "https://glygen.org/publication/PubMed/24683187" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0S6B5", "url": "https://www.uniprot.org/uniprotkb/B0S6B5" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B0S6B5", "url": "https://www.uniprot.org/uniprotkb/B0S6B5" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity.", "journal": "J. 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This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. 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analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_002660900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660900" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S6B8", "url": "https://www.uniprot.org/uniprotkb/B0S6B8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam163aa", "url": "https://www.uniprot.org/uniprotkb/B0S6B8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-416", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-416", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077470", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077470", "database": "Bgee", "categories": [ "Gene 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"categories": [ "Protein Classification" ] }, { "id": "PTHR31914:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31914:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15069", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15069", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:B0S6B8", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:B0S6B8", "database": "PRO", "categories": [ "Protein" ] }, { "id": "XP_002660900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660900", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S6B8", "url": "https://www.uniprot.org/uniprotkb/B0S6B8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S6B8-1", "url": "https://www.uniprot.org/uniprotkb/B0S6B8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-416", "url": "https://zfin.org/ZDB-GENE-070912-416", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKRNESEGEAGSVGDPQPQFACNAYSAPGVDGAAVTPLSLPYDPAQPHSYCPTCSPYYLRSSDEMRNGGERLSYMPTHYENHGATALGLAAMYGPVLSHRSTPDFYTNTRAISTDV", "length": 150, "header": "tr|B0S6B8-1|B0S6B8_DANRE Isoform 1 of Protein FAM163A OS=Danio rerio OX=7955 GN=fam163aa PE=3 SV=1 CANONICAL=B0S6B8-1" }, "isoforms": [ { "isoform_ac": "B0S6B8-1", "url": "https://www.uniprot.org/uniprotkb/B0S6B8/entry#B0S6B8-1", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKRNESEGEAGSVGDPQPQFACNAYSAPGVDGAAVTPLSLPYDPAQPHSYCPTCSPYYLRSSDEMRNGGERLSYMPTHYENHGATALGLAAMYGPVLSHRSTPDFYTNTRAISTDV", "length": 150, "header": "tr|B0S6B8-1|B0S6B8_DANRE Isoform 1 of Protein FAM163A OS=Danio rerio OX=7955 GN=fam163aa PE=3 SV=1 CANONICAL=B0S6B8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100321107", "name": "", "url": 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"MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKGTDDEEAEEEEEAEEHDLSLHPRAPTCNACSSQVLDGRGSLAPLTSESCSQPCGVASHCTTCSPYRTPFYIRTADMVPNGGGGERLSFAPTYYKEGGTPSLKLAAPQSYPVTWPSSGHEAFTNPRAISTDV", "length": 168 }, "evidence": [ { "id": "MGI:3618859", "url": "https://alliancegenome.org/gene/MGI:3618859#orthology", "database": "AGR" }, { "id": "HGNC:28274", "url": "https://alliancegenome.org/gene/HGNC:28274#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CAA5-1", "protein_name": "Protein FAM163A", "gene_name": "Fam163a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKGTDGEDAEEEEEEEEHGLSIHPRVPACNACSSHVLDGRGGLAPLTSESCSQPCGVASHCTTCSPYRTPFYIRTADMVPNGGGGERLSFAPTHYKEGGTPSLKLAAPQNYPVTWPSSGHEAFTNPRAISTDV", "length": 168 }, "evidence": [ { "id": "MGI:3618859", "url": "https://alliancegenome.org/gene/MGI:3618859#orthology", "database": "AGR" }, { "id": "HGNC:28274", "url": "https://alliancegenome.org/gene/HGNC:28274#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-416", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-416#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96GL9-1", "protein_name": "Protein FAM163A", "gene_name": "FAM163A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTAGTVVITGGILATVILLCIIAVLCYCRLQYYCCKKSGTEVADEEEEREHDLPTHPRGPTCNACSSQALDGRGSLAPLTSEPCSQPCGVAASHCTTCSPYSSPFYIRTADMVPNGGGGERLSFAPTYYKEGGPPSLKLAAPQSYPVTWPGSGREAFTNPRAISTDV", "length": 167 }, "evidence": [ { "id": "MGI:3618859", "url": "https://alliancegenome.org/gene/MGI:3618859#orthology", "database": "AGR" }, { "id": "HGNC:28274", "url": "https://alliancegenome.org/gene/HGNC:28274#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-416", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-416#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B0S6B8", "url": "https://www.uniprot.org/uniprotkb/B0S6B8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 38, "end_pos": 40 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0S6B9-1", "uniprot_ac": "B0S6B9", "uniprot_id": "B0S6B9_DANRE", "mass": { "chemical_mass": 124571.0, "monoisotopic_mass": 124571.0 }, "refseq": { "ac": "XP_005171383", "name": "nardilysin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171383" }, "gene_names": [ { "name": "nrd1a", "type": "recommended", "evidence": [ { "id": "B0S6B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6B9" } ] }, { "name": "nrd1a", "type": "synonym", "evidence": [ { "id": "XP_005171383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171383" } ] } ], "protein_names": [ { "name": "Nardilysin", "type": "synonym", "evidence": [ { "id": "B0S6B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6B9/entry#names_and_taxonomy" } ] }, { "name": "nardilysin", "type": "synonym", "evidence": [ { "id": "XP_005171383", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171383" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005171383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171383" } ] } ], "disease": [ { "disease_id": "DOID:1289", "recommended_name": { "id": "DOID:1289", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1289", "name": "neurodegenerative disease", "description": "A central nervous system disease that results in the progressive deterioration of function or structure of neurons." }, "synonyms": [ { "id": "DOID:1289", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1289", "name": "degenerative disease", "description": "" } ], "unlinked_id_list": [ "DOID:0112328", "DOID:0050953", "DOID:0111828", "DOID:0050765", "DOID:681", "DOID:0112322" ], "evidence": [ { "id": "1289", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1289" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S6B9", "url": "https://www.uniprot.org/uniprotkb/B0S6B9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nrd1a", "url": "https://www.uniprot.org/uniprotkb/B0S6B9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-417", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-417", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000019596", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000019596", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "565850", "url": "https://www.ncbi.nlm.nih.gov/gene/565850", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001431", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001431", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007863", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007863", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011249", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011249", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011765", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011765", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "INQVMEH", "url": "https://omabrowser.org/oma/group/INQVMEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S6B9", "url": "https://www.orthodb.org/?gene=B0S6B9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43690", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43690", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43690:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43690:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00675", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00675", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF05193", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05193", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16187", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16187", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005171383", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005171383", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S6B9", "url": "https://www.uniprot.org/uniprotkb/B0S6B9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S6B9-1", "url": "https://www.uniprot.org/uniprotkb/B0S6B9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-417", "url": "https://zfin.org/ZDB-GENE-070912-417", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPQTNKFKCAAASSPAQSAGPDRGEPVRDPNAPPGDSGGDENQGDPQIIKSPSDPKQYRYIELSNGLRALLISDLSGLDGKAEDEDDEDSEEEEAEEEAEGEEEEGDSGEGTDEESEEEGDSQDSDFEELDEESDQKKKKGSEKQSAAALCIGVGSFSDPNDLPGLAHFLEHMVFMGSEKYPSENGFDAFLKKHGGSDNASTDCERTIFQFDVQRKRFKEALDRWAQFFICPLMIEDAIDREVEAVDSEYQLAKPSDSHRKEMLFGSLAKPDHPMSKFCWGNAQTLKTEPKEKNINVYKRLREFWKRHYSAHYMTLAVQSKESLDTLEEWVREIFSQVPNNGQLKPDFSDKLNPFETPAFNKLYRVVPVRKVHALTITWALPPQEKHYRVKPLHYIAWLIGHEGTGSILSMLRRKCWALALFGGNSETGFDQNTTYSIFSISITLTDEGFQNFYEVAHLVFQYLKMLQTLGPQQRIYEEIQKIEANEFHYQEQTDPIEYVEDICENMQLFPKEDFLTGDQLMFEFKPEVISAALNLLTPEKANLLLLSPEHEGQCPLREKWFGTQYSTEDIEQHWREIWAKDFDLNPSLHLPAENKFIATDFALKTSDCPDTEYPVRIMNNDRGCLWYKKDNKFKIPKAYVRFHLISPVVQKSPKNLVLFDLFVNILVHNLAEPAYEADVAQLEYKLVAGEHGLVIKVKGFNHKLPLLFNLIVDYLADFSAAPDVFSMFAEQLKKTYFNILIKPEKLGKDVRLLILEHSRWSTIQKYQAVLDGLSVDELMEFVSGFKSELYAEGLLQGNVTSTESMGFLQYVTEKLQFKKLSVEVPVLFRVVELPQKHHLCKVKSLNKGDANSEVTVYYQSGPKNLREHTLMELLVMHMEEPCFDFLRTKETLGYHVYPTCRNTSGVLGFSVTVETQATKFNTELVETKIEEFLVSFGEKMNSLSDDAFRTQVTALVKLKGCEDTHLGEEVDRNWTEVVTQQYVFDRLSREIDALKLMTKAELVNWFMEHRGEGNRKLSVHVVGYGVEENDPPNDPHPGEEEEASKMSLYGEVSKLTFLQASNLLASVSTITDIRAFTQTLNLFPYHKILK", "length": 1091, "header": "tr|B0S6B9-1|B0S6B9_DANRE Isoform 1 of Nardilysin OS=Danio rerio OX=7955 GN=nrd1a PE=1 SV=1 CANONICAL=B0S6B9-1" }, "isoforms": [ { "isoform_ac": "B0S6B9-1", "url": "https://www.uniprot.org/uniprotkb/B0S6B9/entry#B0S6B9-1", "sequence": { "sequence": "MPQTNKFKCAAASSPAQSAGPDRGEPVRDPNAPPGDSGGDENQGDPQIIKSPSDPKQYRYIELSNGLRALLISDLSGLDGKAEDEDDEDSEEEEAEEEAEGEEEEGDSGEGTDEESEEEGDSQDSDFEELDEESDQKKKKGSEKQSAAALCIGVGSFSDPNDLPGLAHFLEHMVFMGSEKYPSENGFDAFLKKHGGSDNASTDCERTIFQFDVQRKRFKEALDRWAQFFICPLMIEDAIDREVEAVDSEYQLAKPSDSHRKEMLFGSLAKPDHPMSKFCWGNAQTLKTEPKEKNINVYKRLREFWKRHYSAHYMTLAVQSKESLDTLEEWVREIFSQVPNNGQLKPDFSDKLNPFETPAFNKLYRVVPVRKVHALTITWALPPQEKHYRVKPLHYIAWLIGHEGTGSILSMLRRKCWALALFGGNSETGFDQNTTYSIFSISITLTDEGFQNFYEVAHLVFQYLKMLQTLGPQQRIYEEIQKIEANEFHYQEQTDPIEYVEDICENMQLFPKEDFLTGDQLMFEFKPEVISAALNLLTPEKANLLLLSPEHEGQCPLREKWFGTQYSTEDIEQHWREIWAKDFDLNPSLHLPAENKFIATDFALKTSDCPDTEYPVRIMNNDRGCLWYKKDNKFKIPKAYVRFHLISPVVQKSPKNLVLFDLFVNILVHNLAEPAYEADVAQLEYKLVAGEHGLVIKVKGFNHKLPLLFNLIVDYLADFSAAPDVFSMFAEQLKKTYFNILIKPEKLGKDVRLLILEHSRWSTIQKYQAVLDGLSVDELMEFVSGFKSELYAEGLLQGNVTSTESMGFLQYVTEKLQFKKLSVEVPVLFRVVELPQKHHLCKVKSLNKGDANSEVTVYYQSGPKNLREHTLMELLVMHMEEPCFDFLRTKETLGYHVYPTCRNTSGVLGFSVTVETQATKFNTELVETKIEEFLVSFGEKMNSLSDDAFRTQVTALVKLKGCEDTHLGEEVDRNWTEVVTQQYVFDRLSREIDALKLMTKAELVNWFMEHRGEGNRKLSVHVVGYGVEENDPPNDPHPGEEEEASKMSLYGEVSKLTFLQASNLLASVSTITDIRAFTQTLNLFPYHKILK", "length": 1091, "header": "tr|B0S6B9-1|B0S6B9_DANRE Isoform 1 of Nardilysin OS=Danio rerio OX=7955 GN=nrd1a PE=1 SV=1 CANONICAL=B0S6B9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LY70-1", "protein_name": "Nardilysin", "gene_name": "NRDC", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLRRVAVAAVCATGRKLCEAGRELAALSRIEARGRCEDSAAARHFPTLTMPGRNKAKSTCSCPDLQPNGQDLGESGRVARLGADESEEEGRRGPVNNAGDPEIIKSPSDPKQYRYIKLRNGLQALLISDLSNMEGKMGDATDDEEEEEEEEEDDDDDDDDDDDDDDEDSGAEIEDDDEEGFDDEDEFEDDDDEHDDDLDAEDNELEELEERAEARKKTTEKQQLQSLFLLWSKLTDKLWFKSTYTKMSSTQLFKTRNLNGVVGAESRSAPVQHFAGWQEEEQQGETDTVLSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPKRNNTDTHARLREFWLRYYSAHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPKPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSYLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAHTVFQYLKMLQKLGPEKRIFEEIQKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDFLTGDQLLFEYKPEVIAEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSMEDIENSWAELWKSDFELNPDLHLPAENKYIATDFMLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFSSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYSRWSMIDKYRALMDGLSLESLLSFVREFKAQLFVEGLVQGNVTSTESTDFLKYVVDKLNFMPLEQEMPVQFQVVELPSGHHLCKVRALNRGDANSEVTVYYQSGARSLKEYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEDAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTRQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGSKMLSVHVVGFGKYELEEDGTPSGEDSNSSCDVMQLTYLPASPLLVDCTVPIVDIRGFTSRLNLLPYHKIVK", "length": 1231 }, "evidence": [ { "id": "B0S6B9", "url": "https://omabrowser.org/oma/group/B0S6B9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F4HNU6-1", "protein_name": "Nardilysin-like", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MSSMKSVSALDNVVVKSPNDRRLYRVIELENGLCALLIHDPDIYPEGSVPDQIDEDDEDGEEEDSDGSSEDDDDDEDDEEDGEGDEEDEDEDEDEVKGKGDHQTKKAAAAMCVSMGSFLDPPEAQGLAHFLEHMLFMGSTEFPDENEYDSYLSKHGGSSNAYTEMEHTCYHFEVKREFLQGALKRFSQFFVAPLMKTEAMEREVLAVDSEFNQALQNDACRLQQLQCYTSAKGHPFNRFAWGNKKSLSGAMENGVDLRECIVKLYKEYYHGGLMKLVVIGGESLDMLESWVVELFGDVKNGSKIRPTLEAEGPIWKGGKLYRLEAVKDVHILDLTWTLPPLRSAYVKKPEDYLAHLLGHEGRGSLHSFLKAKGWATSLSAGVGDDGINRSSLAYVFGMSIHLTDSGLEKIYDIIGYIYQYLKLLRDVSPQEWIFKELQDIGNMDFRFAEEQPADDYAAELSENMLAYPVEHVIYGDYVYQTWDPKLIEDLMGFFTPQNMRIDVVSKSIKSEEFQQEPWFGSSYIEEDVPLSLMESWSNPSEVDNSLHLPSKNQFIPCDFSIRAINSDVDPKSQSPPRCIIDEPFMKFWYKLDETFKVPRANTYFRINLKGAYASVKNCLLTELYINLLKDELNEIIYQASIAKLETSLSMYGDKLELKVYGFNEKIPALLSKILAIAKSFMPNLERFKVIKENMERGFRNTNMKPLNHSTYLRLQLLCKRIYDSDEKLSVLNDLSLDDLNSFIPELRSQIFIEALCHGNLSEDEAVNISNIFKDSLTVEPLPSKCRHGEQITCFPMGAKLVRDVNVKNKSETNSVVELYYQIEPEEAQSTRTKAVLDLFHEIIEEPLFNQLRTKEQLGYVVECGPRLTYRVHGFCFCVQSSKYGPVHLLGRVDNFIKDIEGLLEQLDDESYEDYRSGMIARLLEKDPSLLSETNDLWSQIVDKRYMFDFSHKEAEELRSIQKKDVISWYKTYFRESSPKCRRLAVRVWGCDTNMKETQTDQKAVQVIADAVAFKSTSKFYPSLC", "length": 1024 }, "evidence": [ { "id": "B0S6B9", "url": "https://omabrowser.org/oma/group/B0S6B9/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "O43847-1", "protein_name": "Nardilysin", "gene_name": "NRDC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRRVTVAAVCATRRKLCEAGRELAALWGIETRGRCEDSAAARPFPILAMPGRNKAKSTCSCPDLQPNGQDLGENSRVARLGADESEEEGRRGSLSNAGDPEIVKSPSDPKQYRYIKLQNGLQALLISDLSNMEGKTGNTTDDEEEEEVEEEEEDDDEDSGAEIEDDDEEGFDDEDEFDDEHDDDLDTEDNELEELEERAEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPRKNNIDTHARLREFWMRYYSSHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPRPNFGHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSFLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAYTVFQYLKMLQKLGPEKRIFEEIRKIEDNEFHYQEQTDPVEYVENMCENMQLYPLQDILTGDQLLFEYKPEVIGEALNQLVPQKANLVLLSGANEGKCDLKEKWFGTQYSIEDIENSWAELWNSNFELNPDLHLPAENKYIATDFTLKAFDCPETEYPVKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLAEFNSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYARWSMIDKYQALMDGLSLESLLSFVKEFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFKPLEQEMPVQFQVVELPSGHHLCKVKALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSEVVDKKIEEFLSSFEEKIENLTEEAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVNWFKAHRGPGSKMLSVHVVGYGKYELEEDGTPSSEDSNSSCEVMQLTYLPTSPLLADCIIPITDIRAFTTTLNLLPYHKIVK", "length": 1151 }, "evidence": [ { "id": "FB:FBgn0037037", "url": "https://alliancegenome.org/gene/FB:FBgn0037037#orthology", "database": "AGR" }, { "id": "RGD:3210", "url": "https://alliancegenome.org/gene/RGD:3210#orthology", "database": "AGR" }, { "id": "HGNC:7995", "url": "https://alliancegenome.org/gene/HGNC:7995#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-417", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-417#orthology", "database": "AGR" }, { "id": "MGI:1201386", "url": "https://alliancegenome.org/gene/MGI:1201386#orthology", "database": "AGR" }, { "id": "FB:FBgn0030344", "url": "https://alliancegenome.org/gene/FB:FBgn0030344#orthology", "database": "AGR" }, { "id": "B0S6B9", "url": "https://omabrowser.org/oma/group/B0S6B9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P40851-1", "protein_name": "A-factor-processing protease AXL1", "gene_name": "AXL1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSLREVTNYEVSFYIPLSYSNRTHKVCKLPNGILALIISDPTDTSSSCSLTVCTGSHNDPKDIAGLAHLCEHMILSAGSKKYPDPGLFHTLIAKNNGSQNAFTTGEQTTFYFELPNTQNNGEFTFESILDVFASFFKEPLFNPLLISKEIYAIQSEHEGNISSTTKIFYHAARILANPDHPFSRFSTGNIHSLSSIPQLKKIKLKSSLNTYFENNFFGENITLCIRGPQSVNILTKLALSKFGDIKPKSAVKERSISIRTRSFRRSKSLKKRQDSSKNDYSDLKTFKILNTTWEKKYKNTMCFQQFPECNSIFINSNKVPIMRLLFPVSDKNTRFTKDDIKIYSHLWCELFGDESPGSLSYYLASKGWLTGCFAFTSEFAIGDIGLILELELTNSGWENIKRITTIVLNRLLPSFYVMNIDYLITFLKEQNLIDLVSFLYQSSEDLPMEECSKLSGILQDDLECLTPPNIFKGFKSLIEIDDPNIEKYENTKANIQWWTGQAIKFQNFLKSFMNHDNMRLLLLGNIKSGNIFDKMKNKSDICTDFFYEFEYYTANVHLASDNKFHSNSSYEFNFPTGNLFLPDCVSDPLKLQQLFLECSLKSKFATLRPQIYSEPTRTKPQLVSENQNYEMWILKEDPNFASDNKSVVSFEVLGLGIKPSPEATIHLEVLAQALFIITSSFLYPALRIGYTYEIASSSKGNVTLRFTISGFPEGVFTIVKTFVDTLKLIATDPTFLSKDTLRKARILVRNKYKNASSDNCVKLASVGLLIVLEKYIWTLEDRINALELTELESFEKFCFLFWRNPKHLVLFMQGSLEYADAINRYLNNNFTQHLKISNEGSKPTIRLYPPPSTKDLDQGTNAFISYNGHQDDPNNSIVYFIQTAQRDDIKNLTLTFLTEYLFSLTLVPDLRNKKQIGYIVLGGLRVLTDTVGIHITVMSGSSGHNLETRINEYLSYLQLQVLNRFTEFDFRRILLEPFLNLLKQNSTKQFEGSAGPVDLLNEIVANVQNGDNYTLNNKQMRQHRKVRNKIAEGRLNFQEDHEMIDISFLQKLTLKKYLAFFESKISIYSAQRSKLSIMITSPMAEKEIASRKMFLQLEAFLKINGFAIKNEDLKKIVEHSKGNPILLVKNLFTYFRRRNEVFKLGTVVLQEILKIIGMNLKQRYGSILGFSSQDGEGQEIEKFWNNDTSPIVPLQELPEPNFFRKAAF", "length": 1208 }, "evidence": [ { "id": "FB:FBgn0037037", "url": "https://alliancegenome.org/gene/FB:FBgn0037037#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P47245-1", "protein_name": "Nardilysin", "gene_name": "Nrdc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRRVAVAAVFATGRKLRCEAGRDVTAVGRIEARGLCEESAKPFPTLTMPGRNKAKSTCSCPDLQPNGQDLGESGRVARLGADESEEEGRSLSNVGDPEIIKSPSDPKQYRYIKLQNGLQALLISDLSNVEGKTGNATDEEEEEEEEEEEGEEEEEEEEDDDDDDDEDSGAEIQDDDEEGFDDEEEFDDDEHDDDDLDNEENELEELEERVEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPKKNNIDTHARLREFWMRYYSAHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPKPNFSHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSYLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAHTVFQYLKMLQKLGPEKRVFEEIQKIEDNEFHYQEQTDPVEYVENMCENMQLYPRQDFLTGDQLLFEYKPEVIAEALNQLVPQKANLVLLSGANEGRCDLKEKWFGTQYSIEDIENSWTELWKSNFDLNSDLHLPAENKYIATDFTLKAFDCPETEYPAKIVNTPQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLTEFSSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYSRWSMIDKYRALMDGLSLESLLNFVKDFKSQLFVEGLVQGNVTSTESMDFLRYVVDKLNFVPLEREMPVQFQVVELPSGHHLCKVRALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSETVDKKIEEFLSSFEEKIENLTEDAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVSWFKAHRGPGSKMLSVHVVGYGKYELEEDGAPVCEDPNSREGMQLIYLPPSPLLAESTTPITDIRAFTATLSLFPYHKIVK", "length": 1161 }, "evidence": [ { "id": "FB:FBgn0037037", "url": "https://alliancegenome.org/gene/FB:FBgn0037037#orthology", "database": "AGR" }, { "id": "RGD:3210", "url": "https://alliancegenome.org/gene/RGD:3210#orthology", "database": "AGR" }, { "id": "HGNC:7995", "url": "https://alliancegenome.org/gene/HGNC:7995#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-417", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-417#orthology", "database": "AGR" }, { "id": "MGI:1201386", "url": "https://alliancegenome.org/gene/MGI:1201386#orthology", "database": "AGR" }, { "id": "FB:FBgn0030344", "url": "https://alliancegenome.org/gene/FB:FBgn0030344#orthology", "database": "AGR" }, { "id": "B0S6B9", "url": "https://omabrowser.org/oma/group/B0S6B9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1L985-1", "protein_name": "3.4.24.61", "gene_name": "nrd1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPQMSKAKSCGCNVTCEVSGPDSGEPPPAVTEPQESDAADSNTIIKSPNDYKTYRYIELSNGLKALLISDVSSQSESCRESVDKEVEEEGDRGSASDISKHSERGKQSCRSEKQSAAALCISVGSFSDPADLPGLAHFLEHMVFMGSEKYPVENGFDAFLKKHGGSDNASTDCERTIFQFDVQRKYLREALDRWAQFFICPLMIPDAVDREVEAVDSEYQMAQPLDSNRKEMLFGSLAKAGHPMSKFFWGNAQTLKQEPREKKINTYERLRDFWRRYYSAQYMTLAVQSKETLDTLEEWVREIFVQIPNNGLPKADFSDLQDPFDTPDFCKLYRVVPVQKVHALTISWALPPQAKHYRVKPLHYISWLIGHEGVGSVLSLLRKRCWALSLFGGNSESGFDQNSTYSIFSISITLSDEGLQNFLQVIHIIFQYLKMLQSVGPQQRIYEEIQKIEANEFHYQEQTEPIEFVANMSENMQLFPKEHFLCGDQLMFDFNPEASHCVISAALSLLTPGKANILLLSPQHDGLCPLKEKWFGTQYSVEDIPQEFRDLWAGDFPLHPELQLPAENKFIATDFTLRTSDCPDTDFPVKIIDNERGRLWFRKDNKFKIPKAYARFQLLTPFIQESPKNLVLFDLFVNIVAHNLAELAYDAEVAQLQYNLLPGDHGLFIRLKGFNHKLPLLLKLIVDHLADFSATPDVFNMFIEQLKKTYYIILIRPERLGKDVRLQILEHHRWSVMQKYEAIMADPSVADLMTFANRFKAELFVEGLVQGNFTSAESKEFLQCFIEKLKYAPHPIEPPVLFRVVELPQTHHLCKVQSLNKADANSEVTVYYQTGLKNLREHTLMELLVMHMEEPCFDFLRTKETLGYQVYPICRNTSGILGFSVTVETQATKFSTDFVEGKIEAFLVSFGEKLVQLSDEAFGAQVTALIKLKECEDTQLGDEVDRNWFEVVTQQYVFDRLNKEIEILKDVTKDELVSFYMEHRKENSRKLSIHVVGFGEEEKEIHGEDQCSSNPETSSYANISKLTFLSAAAMKEKSTMITDIRAFTSSLHLHPYHKILI", "length": 1061 }, "evidence": [ { "id": "HGNC:7995", "url": "https://alliancegenome.org/gene/HGNC:7995#orthology", "database": "AGR" }, { "id": "MGI:1201386", "url": "https://alliancegenome.org/gene/MGI:1201386#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BHG1-1", "protein_name": "Nardilysin", "gene_name": "Nrdc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRRVAVAAVCVTGRKLRCEAGRELTALGRIEARGLCEESSKPFPTLTMPGRNKAKSTCSCPDLQPNGQDLGESGRLARLGADESEEEGRSFSNVGDPEIIKSPSDPKQYRYIKLQNGLQALLISDLSNVEGKTGNATDEEEEEEEEEEEEDDDDDDDDDDDDEDSGAEIQDDDEEGFDDEEEFDDDDDDEHDDDDLENEENELEELEERVEARKKTTEKQSAAALCVGVGSFADPDDLPGLAHFLEHMVFMGSLKYPDENGFDAFLKKHGGSDNASTDCERTVFQFDVQRKYFKEALDRWAQFFIHPLMIRDAIDREVEAVDSEYQLARPSDANRKEMLFGSLARPGHPMGKFFWGNAETLKHEPKKNNIDTHARLREFWMRYYSAHYMTLVVQSKETLDTLEKWVTEIFSQIPNNGLPKPNFSHLTDPFDTPAFNKLYRVVPIRKIHALTITWALPPQQQHYRVKPLHYISWLVGHEGKGSILSYLRKKCWALALFGGNGETGFEQNSTYSVFSISITLTDEGYEHFYEVAHTVFQYLKMLQKLGPEKRVFEEIQKIEDNEFHYQEQTDPVEYVENMCENMQLYPRQDFLTGDQLLFEYKPEVIAEALNQLVPQKANLVLLSGANEGRCDLKEKWFGTQYSIEDIENSWTELWKSNFDLNPDLHLPAENKYIATDFTLKAFDCPETEYPAKIVNTAQGCLWYKKDNKFKIPKAYIRFHLISPLIQKSAANVVLFDIFVNILTHNLAEPAYEADVAQLEYKLVAGEHGLIIRVKGFNHKLPLLFQLIIDYLTEFSSTPAVFTMITEQLKKTYFNILIKPETLAKDVRLLILEYSRWSMIDKYQALMDGLSLDSLLNFVKDFKSQLFVEGLVQGNVTSTESMDFLKYVVDKLNFAPLEREMPVQFQVVELPSGHHLCKVRALNKGDANSEVTVYYQSGTRSLREYTLMELLVMHMEEPCFDFLRTKQTLGYHVYPTCRNTSGILGFSVTVGTQATKYNSETVDKKIEEFLSSFEEKIENLTEDAFNTQVTALIKLKECEDTHLGEEVDRNWNEVVTQQYLFDRLAHEIEALKSFSKSDLVSWFKAHRGPGSKMLSVHVVGYGKYELEEDGAPFGEDSNSREGMQLTYLPPSPVLAESTTPITDIRAFTATLSLFPYHKIVK", "length": 1161 }, "evidence": [ { "id": "FB:FBgn0037037", "url": "https://alliancegenome.org/gene/FB:FBgn0037037#orthology", "database": "AGR" }, { "id": "RGD:3210", "url": "https://alliancegenome.org/gene/RGD:3210#orthology", "database": "AGR" }, { "id": "HGNC:7995", "url": "https://alliancegenome.org/gene/HGNC:7995#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-417", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-417#orthology", "database": "AGR" }, { "id": "MGI:1201386", "url": "https://alliancegenome.org/gene/MGI:1201386#orthology", "database": "AGR" }, { "id": "FB:FBgn0030344", "url": "https://alliancegenome.org/gene/FB:FBgn0030344#orthology", "database": "AGR" }, { "id": "B0S6B9", "url": "https://omabrowser.org/oma/group/B0S6B9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VP94-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG10588", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MCFRPRLGLRRITKQVQKWLNRQQYPMSTASVVVQYHEEPDKSDGDSKLYRALTLSNGLRAMLISDSYIDEPSIHRASRESLNSSTENFNGKLAACAVLVGVGSFSEPQQYQGLAHFVEHMIFMGSEKFPVENEFDSFVTKSGGFSNAHTENEETCFYFELDQTHLDRGMDLFMNLMKAPLMLPDAMSRERSAVQSEFEQTHMRDEVRRDQILASLASEGYPHGTFSWGNYKTLKEGVDDSSLHKELHKFYRDHYGSNRMVVALQAQLSLDELEELLVRHCADIPTSQQNSIDVSQLNYQKAFRDQFYKDVFLVQPVEDVCKLELTWVLPPMKNFYRSKPDMFISQLIGYEGVGSLCAYLRHHLWCISVVAGVAESSFDSNSIYSLFNICIYLSDDGFDHIDEVLEATFAWVKLIINSDQLQDSYKESQQIENNNFRFQIEPPPIDHVQSIVESFNYLPSKDVLTGPQLYFQYEESAIELLRQHMNKFNFNIMISSYIPYEKNEYDQREPWFGTQFKTISMPPKWQTMWEQSATIKELHYPQPNPFVTTDFKIHWVESGKPHVSRSPKALIRNDLCELWFRQDNIFKLPDGYINLYFITPLVRESVKQYMLGVLFTYLVEFRMAEQLYPALEAGLTYGLYIGDKGLVMRVSGYNEKLPLLVEIILNMMQTIELDIGQVNAFKDLKKRQIYNALINGKSLNLDLRLSILENKRFSMISKYESVDDITMDDIKSFKENFHKKMYVKGLIQGNFTEDQATDLMQKVLDTYKSEKLDNLSALDNHLLQIPLGSYYLRAKTLNEDDSNTIITNYYQIGPSDLKMECIMDLVELIVEEPFFNQLRTQEQLGYSLGIHQRIGYGVLAFLITINTQETKHRADYVEQRIEAFRSRMAELVSQMSDTEFKNIRETLINGKKLGDTSLDEEVLRNWSEIVTKEYFFNRIETQIQMLSHLTKEDVLNFLNDNDKNNLRKLSVQVVGNHNQTSNSTAQASRSGSLSDLLDDVQDNMANETDSAKPMTDKIRLEFLGESDDPSSIKDIYAFKKDLYVFPLFNTNPNLANKS", "length": 1058 }, "evidence": [ { "id": "FB:FBgn0037037", "url": "https://alliancegenome.org/gene/FB:FBgn0037037#orthology", "database": "AGR" }, { "id": "RGD:3210", "url": "https://alliancegenome.org/gene/RGD:3210#orthology", "database": "AGR" }, { "id": "HGNC:7995", "url": "https://alliancegenome.org/gene/HGNC:7995#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-417", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-417#orthology", "database": "AGR" }, { "id": "MGI:1201386", "url": "https://alliancegenome.org/gene/MGI:1201386#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VYT3-1", "protein_name": "3.4.24.-", "gene_name": "Nrd1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLWQRYSAHLFRRFEFHVRTKRRSPITQLAGVRAITYSSLCKMTDQVKYLDIPDKSETDKKLYKTLLLGNGLHALIVSDPSPMPHDGFTTSESSSSKSTVSTSSSIISRSESTSSTSTDSESSEESSSEEGDEKLAACALLIDYGSFAEPTKYQGLAHFLEHMIFMGSEKYPKENIFDAHIKKCGGFANANTDCEDTLFYFEVAEKHLDSSLDYFTALMKAPLMKQEAMQRERSAVDSEFQQILQDDETRRDQLLASLATKGFPHGTFAWGNMKSLKENVDDAELHKILHEIRKEHYGANRMYVCLQARLPIDELESLVVRHFSGIPHNEVKAPDLSSFNYKDAFKAEFHEQVFFVKPVENETKLELTWVLPNVRQYYRSKPDQFLSYLLGYEGRGSLCAYLRRRLWALQLIAGIDENGFDMNSMYSLFNICIYLTDEGFKNLDEVLAATFAYVKLFANCGSMKDVYEEQQRNEETGFRFHAQRPAFDNVQELVLNLKYFPPKDILTGKELYYEYNEEHLKELISHLNEMKFNLMVTSRRKYDDISAYDKTEEWFGTEYATIPMPEKWRKLWEDSVPLPELFLPESNKYVTDDFTLHWHSMGRPEVPDSPKLLIKTDTCELWFRQDDKFDLPEAHMAFYFISPMQRQNAKNDAMCSLYEEMVRFHVCEELYPAISAGLSYSLSTIEKGLLLKVCGYNEKLHLIVEAIAEGMLNVAETLDENMLSAFVKNQRKAFFNALIKPKALNRDIRLCVLERIRWLMINKYKCLSSVILEDMREFAHQFPKELYIQSLIQGNYTEESAHNVMNSLLSRLNCKQIRERGRFLEDITVKLPVGTSIIRCHALNVQDTNTVITNFYQIGPNTVRVESILDLLMMFVDEPLFDQLRTKEQLGYHVGATVRLNYGIAGYSIMVNSQETKTTADYVEGRIEVFRAKMLQILRHLPQDEYEHTRDSLIKLKLVADLALSTEMSRNWDEIINESYLFDRRRRQIEVLRTLQKDEIINFVISIDGDNMRKLSVQVIGHRPAGMPEPLCGEDTAKCASKSDDESESENDDDDDEDEEEEESSEEEEEEEKEKEGLKGEDEDDLFYSLENKLNIVFLPAKFNNAFIITDIEKFKDDQYVYPQQKTQPKEEDELISAHIADAIRQV", "length": 1147 }, "evidence": [ { "id": "RGD:3210", "url": "https://alliancegenome.org/gene/RGD:3210#orthology", "database": "AGR" }, { "id": "HGNC:7995", "url": "https://alliancegenome.org/gene/HGNC:7995#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-417", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-417#orthology", "database": "AGR" }, { "id": "MGI:1201386", "url": "https://alliancegenome.org/gene/MGI:1201386#orthology", "database": "AGR" }, { "id": "FB:FBgn0030344", "url": "https://alliancegenome.org/gene/FB:FBgn0030344#orthology", "database": "AGR" }, { "id": "B0S6B9", "url": "https://omabrowser.org/oma/group/B0S6B9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metalloendopeptidase activity", "id": "GO:0004222", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004222", "evidence": [ { "database": "UniProtKB", "id": "B0S6B9", "url": "https://www.uniprot.org/uniprotkb/B0S6B9" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "B0S6B9", "url": "https://www.uniprot.org/uniprotkb/B0S6B9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial matrix", "id": "GO:0005759", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005759", "evidence": [ { "database": "UniProtKB", "id": "B0S6B9", "url": "https://www.uniprot.org/uniprotkb/B0S6B9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "B0S6B9", "url": "https://www.uniprot.org/uniprotkb/B0S6B9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" }, { "start_pos": 433, "end_pos": 435, "annotation": "n_glycosylation_sequon" }, { "start_pos": 799, "end_pos": 801, "annotation": "n_glycosylation_sequon" }, { "start_pos": 903, "end_pos": 905, "annotation": "n_glycosylation_sequon" }, { "start_pos": 974, "end_pos": 976, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0S6B9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6B9" }, { "id": "PF22456", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22456" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Coenzyme PQQ synthesis protein F-like C-terminal lobe", "eco_id": "ECO_0000259", "start_pos": 875, "end_pos": 975, "start_aa": "Leu", "end_aa": "Trp", "glycosite_overlap": "" }, { 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"Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16187" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase M16 middle/third", "eco_id": "ECO_0000259", "start_pos": 488, "end_pos": 769, "start_aa": "Phe", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 199, "end_pos": 201 }, { "start_pos": 433, "end_pos": 435 }, { "start_pos": 799, "end_pos": 801 }, { "start_pos": 903, "end_pos": 905 }, { "start_pos": 974, "end_pos": 976 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", 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"B0S6J4_DANRE", "mass": { "chemical_mass": 16428.0, "monoisotopic_mass": 16428.0 }, "refseq": { "ac": "NP_001013563", "name": "protein FAM72A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013563" }, "gene_names": [ { "name": "zgc:101564", "type": "synonym", "evidence": [ { "id": "NP_001013563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013563" }, { "id": "B0S6J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6J4" } ] } ], "protein_names": [ { "name": "Protein FAM72A", "type": "synonym", "evidence": [ { "id": "B0S6J4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6J4/entry#names_and_taxonomy" } ] }, { "name": "protein FAM72A", "type": "synonym", "evidence": [ { "id": "NP_001013563", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013563" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01008863.1, SRR26395050.657739.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On or before Feb 13, 2016 this sequence version replaced XP_005172931.1, NP_001013563.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference genome strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001013563", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013563" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S6J4", "url": "https://www.uniprot.org/uniprotkb/B0S6J4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/B0S6J4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050320-120", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050320-120", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000070621", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000070621", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "541418", "url": "https://www.ncbi.nlm.nih.gov/gene/541418", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:541418", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:541418", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HLWIFNS", "url": "https://omabrowser.org/oma/group/HLWIFNS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S6J4", "url": "https://www.orthodb.org/?gene=B0S6J4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31841", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31841", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31841:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31841:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001013563", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013563", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S6J4", "url": "https://www.uniprot.org/uniprotkb/B0S6J4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S6J4-1", "url": "https://www.uniprot.org/uniprotkb/B0S6J4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050320-120", "url": "https://zfin.org/ZDB-GENE-050320-120", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSTSNFKNKCVTQINCIYCDSLLCTRGMKAVLLADTEIELFSTDIPPNRTVDFVASCYSTESCKCKLRDIACLKCGNVVGYHVVAPCKPCLLSCNNGHFWMFNSEAVSTINRLDATGQNLLLWGDLPELEDSDDESLESFSEEEYLR", "length": 147, "header": "tr|B0S6J4-1|B0S6J4_DANRE Isoform 1 of Protein FAM72A OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=B0S6J4-1" }, "isoforms": [ { "isoform_ac": "B0S6J4-1", "url": "https://www.uniprot.org/uniprotkb/B0S6J4/entry#B0S6J4-1", "sequence": { "sequence": "MSTSNFKNKCVTQINCIYCDSLLCTRGMKAVLLADTEIELFSTDIPPNRTVDFVASCYSTESCKCKLRDIACLKCGNVVGYHVVAPCKPCLLSCNNGHFWMFNSEAVSTINRLDATGQNLLLWGDLPELEDSDDESLESFSEEEYLR", "length": 147, "header": "tr|B0S6J4-1|B0S6J4_DANRE Isoform 1 of Protein FAM72A OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=B0S6J4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2002", "authors": "Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA", "evidence": [ { "database": "UniProtKB", "id": "B0S6J4", "url": "https://www.uniprot.org/uniprotkb/B0S6J4" } ], "reference": [ { "type": "PubMed", "id": "12477932", "url": "https://glygen.org/publication/PubMed/12477932" } ] }, { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "B0S6J4", "url": "https://www.uniprot.org/uniprotkb/B0S6J4" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] }, { "title": "Evaluation of CRISPR gene-editing tools in zebrafish.", "journal": "BMC Genomics", "date": "2022", "authors": "Uribe-Salazar Jos\u00e9 M, Kaya Gulhan, Sekar Aadithya, Weyenberg KaeChandra, Ingamells Cole, Dennis Megan Y", "evidence": [ { "database": "UniProtKB", "id": "B0S6J4", "url": "https://www.uniprot.org/uniprotkb/B0S6J4" } ], "reference": [ { "type": "PubMed", "id": "34986794", "url": "https://glygen.org/publication/PubMed/34986794" } ] } ], "pathway": [ { "id": "dre:541418", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:541418", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7HK37-1", "protein_name": "Protein 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"id": "ZFIN:ZDB-GENE-050320-120", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050320-120#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5TYM5-1", "protein_name": "Protein FAM72A", "gene_name": "FAM72A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSTNICSFKDRCVSILCCKFCKQVLSSRGMKAVLLADTEIDLFSTDIPPTNAVDFTGRCYFTKICKCKLKDIACLKCGNIVGYHVIVPCSSCLLSCNNGHFWMFHSQAVYDINRLDSTGVNVLLWGNLPEIEESTDEDVLNISAEECIR", "length": 149 }, "evidence": [ { "id": "RGD:1598023", "url": "https://alliancegenome.org/gene/RGD:1598023#orthology", "database": "AGR" }, { "id": "MGI:1919669", "url": "https://alliancegenome.org/gene/MGI:1919669#orthology", "database": "AGR" }, { "id": "HGNC:24044", "url": "https://alliancegenome.org/gene/HGNC:24044#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050320-120", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050320-120#orthology", "database": "AGR" }, { "id": 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record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000009.1. On or before Apr 11, 2008 this sequence version replaced XP_697453.1, XP_001338673.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001116765", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116765" } ] }, { "annotation": "Crystallins are the dominant structural components of the vertebrate eye lens.", "evidence": [ { "database": "UniProtKB", "id": "B0S6N1", "url": "https://www.uniprot.org/uniprotkb/B0S6N1#function" }, { "database": "UniProtKB", "id": "ARBA00003689", "url": "https://www.uniprot.org/uniprotkb/ARBA00003689#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S6N1", "url": "https://www.uniprot.org/uniprotkb/B0S6N1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "crygm2d21", "url": "https://www.uniprot.org/uniprotkb/B0S6N1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081105-133", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-133", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000086658", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000086658", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "569000", "url": "https://www.ncbi.nlm.nih.gov/gene/569000", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001064", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001064", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050252", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050252", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569000", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569000", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IMDSWYI", "url": "https://omabrowser.org/oma/group/IMDSWYI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S6N1", "url": "https://www.orthodb.org/?gene=B0S6N1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11818:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11818:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00030", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00030", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001116765", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116765", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S6N1", "url": "https://www.uniprot.org/uniprotkb/B0S6N1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S6N1-1", "url": "https://www.uniprot.org/uniprotkb/B0S6N1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081105-133", "url": "https://zfin.org/ZDB-GENE-081105-133", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKVTFFEDRNFQGRSYECMGDCGDFSSYMSRCHSCRVDSGCWMMYDQPNYMGSGYFFRRGEYADYMSMFGMNNCIRSCRMIPMHRGSYRMRIYERDNFMGQMYEMMDDCDNIMDRYRMSHCQSCHVMDGHWLFYDQPHYRGRMWHFGPGQYRNFSNYGGMRFMSMRRIMDSWY", "length": 173, "header": "tr|B0S6N1-1|B0S6N1_DANRE Isoform 1 of Crystallin, gamma M2d21 OS=Danio rerio OX=7955 GN=crygm2d21 PE=3 SV=1 CANONICAL=B0S6N1-1" }, "isoforms": [ { "isoform_ac": "B0S6N1-1", "url": "https://www.uniprot.org/uniprotkb/B0S6N1/entry#B0S6N1-1", "sequence": { "sequence": "MKVTFFEDRNFQGRSYECMGDCGDFSSYMSRCHSCRVDSGCWMMYDQPNYMGSGYFFRRGEYADYMSMFGMNNCIRSCRMIPMHRGSYRMRIYERDNFMGQMYEMMDDCDNIMDRYRMSHCQSCHVMDGHWLFYDQPHYRGRMWHFGPGQYRNFSNYGGMRFMSMRRIMDSWY", "length": 173, "header": "tr|B0S6N1-1|B0S6N1_DANRE Isoform 1 of Crystallin, gamma M2d21 OS=Danio rerio OX=7955 GN=crygm2d21 PE=3 SV=1 CANONICAL=B0S6N1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Translation initiation factor eIF3h targets specific transcripts to polysomes during embryogenesis.", "journal": "Proc. 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Toxicol.", "date": "2018", "authors": "Arcanjo Caroline, Armant Olivier, Floriani Magali, Cavalie Isabelle, Camilleri Virginie, Simon Olivier, Orjollet Daniel, Adam-Guillermin Christelle, Gagnaire B\u00e9atrice", "evidence": [ { "database": "UniProtKB", "id": "B0S6N1", "url": "https://www.uniprot.org/uniprotkb/B0S6N1" } ], "reference": [ { "type": "PubMed", "id": "29751158", "url": "https://glygen.org/publication/PubMed/29751158" } ] }, { "title": "Single cell transcriptomics of the developing zebrafish lens and identification of putative controllers of lens development.", "journal": "Exp. 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"UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q5P9-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1489, "header": "tr|F1Q5P9-1|F1Q5P9_DANRE Isoform 1 of Uncharacterized protein si:ch211-214b16.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=2 CANONICAL=F1Q5P9-1" }, "isoforms": [ { "isoform_ac": "A0AB32TI81-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AB32TI81-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1452, "header": "tr|A0AB32TI81-1|F1Q5P9_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AB32TPP7-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AB32TPP7-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1452, "header": "tr|A0AB32TPP7-1|F1Q5P9_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AB32TQ43-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AB32TQ43-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1452, "header": "tr|A0AB32TQ43-1|F1Q5P9_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AB32TQB0-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AB32TQB0-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1488, "header": "tr|A0AB32TQB0-1|F1Q5P9_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AB32TRT4-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AB32TRT4-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1453, "header": "tr|A0AB32TRT4-1|F1Q5P9_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J3X8-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J3X8-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1415, "header": "tr|A0AC58J3X8-1|A0AC58J3X8_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X10 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J3Y2-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J3Y2-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1451, "header": "tr|A0AC58J3Y2-1|A0AC58J3Y2_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X9 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J3Y4-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J3Y4-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1451, "header": "tr|A0AC58J3Y4-1|A0AC58J3Y4_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X8 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J3Y7-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J3Y7-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1415, "header": "tr|A0AC58J3Y7-1|A0AC58J3Y7_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X16 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J3Z0-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J3Z0-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLSRI", "length": 1131, "header": "tr|A0AC58J3Z0-1|A0AC58J3Z0_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X23 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J3Z1-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J3Z1-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1452, "header": "tr|A0AC58J3Z1-1|A0AC58J3Z1_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X7 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J3Z2-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J3Z2-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1416, "header": "tr|A0AC58J3Z2-1|A0AC58J3Z2_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X14 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J3Z6-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J3Z6-1", "sequence": { "sequence": "MEDKLQSVKRIWFLCFHCSKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1266, "header": "tr|A0AC58J3Z6-1|A0AC58J3Z6_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X20 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J3Z7-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J3Z7-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLSRI", "length": 1132, "header": "tr|A0AC58J3Z7-1|A0AC58J3Z7_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X22 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J3Z8-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J3Z8-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1416, "header": "tr|A0AC58J3Z8-1|A0AC58J3Z8_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X13 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J400-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J400-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLSRI", "length": 1058, "header": "tr|A0AC58J400-1|A0AC58J400_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X30 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J404-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J404-1", "sequence": { "sequence": "MEDKLQSVKRIWFLCFHCSKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1265, "header": "tr|A0AC58J404-1|A0AC58J404_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X21 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J405-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J405-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1378, "header": "tr|A0AC58J405-1|A0AC58J405_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X12 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J406-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J406-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1415, "header": "tr|A0AC58J406-1|A0AC58J406_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X17 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J407-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J407-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1377, "header": "tr|A0AC58J407-1|A0AC58J407_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X18 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J409-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J409-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLSRI", "length": 1094, "header": "tr|A0AC58J409-1|A0AC58J409_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X28 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J410-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J410-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLSRI", "length": 1020, "header": "tr|A0AC58J410-1|A0AC58J410_DANRE Computationally mapped isoform of Protein NLRC3 isoform X33 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J411-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J411-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1415, "header": "tr|A0AC58J411-1|A0AC58J411_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X15 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J413-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J413-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRFGIFLLPFF", "length": 1099, "header": "tr|A0AC58J413-1|A0AC58J413_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X24 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J414-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J414-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLSRI", "length": 1094, "header": "tr|A0AC58J414-1|A0AC58J414_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X27 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J418-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J418-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1414, "header": "tr|A0AC58J418-1|A0AC58J418_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X19 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J419-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J419-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLSRI", "length": 1095, "header": "tr|A0AC58J419-1|A0AC58J419_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X26 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J423-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J423-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRFGIFLLPFF", "length": 1027, "header": "tr|A0AC58J423-1|A0AC58J423_DANRE Computationally mapped isoform of Protein NLRC3 isoform X31 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J425-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J425-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1414, "header": "tr|A0AC58J425-1|A0AC58J425_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-214b16.3 isoform X11 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J426-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J426-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRFGIFLLPFF", "length": 1063, "header": "tr|A0AC58J426-1|A0AC58J426_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X29 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J433-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J433-1", "sequence": { "sequence": 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"length": 1026, "header": "tr|A0AC58J433-1|A0AC58J433_DANRE Computationally mapped isoform of Protein NLRC3 isoform X32 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "A0AC58J443-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#A0AC58J443-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLINRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRFGIFLLPFF", "length": 1062, "header": "tr|A0AC58J443-1|A0AC58J443_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 3 isoform X25 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=1 CANONICAL=F1Q5P9-1" }, "locus": {} }, { "isoform_ac": "F1Q5P9-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9/entry#F1Q5P9-1", "sequence": { "sequence": "MERKAKHPCEMSVFEEREREAFIQTVRAVSPLSSCVSMMCNHSIGLPPDRSDGAVSSDFVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWERTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMFIKSDHPFGLPLYLSDRAVNSDSVWKRTRSPLSSCVSMKSNNSMGLPPDLSDGAVNSEFLKRKREESSLSSSMSMKSDHYIDLPPCKLISNRKRESSPLSSCVSMKSNHSMSLPPYLSDGAVNSDSVSPYYQKHISHFKTEACLMIDSQQLVHDDLQRVKDQHRFIMKIKYESLFEGVKLQQNQTLLNSIYTQLYIIEGESEGVNEEHEVLQMEKRYKTLQDTPINCNDIFNPSAEAGDEEKSREEKEQIKTVLTKGIAGIGKTVSVQKFILDWAEGKANQDVDFIFVLPFRELNLIKDHQYSLHTLLLDFHPELQHLDSQIYEECKVVFIFDGLDESRITLMFSDCQKVSDVTEASSVSVLMSNLMKGDLLPSALIWITSRPAAANQIPSKHISLVTEIQGFNDPQKEEYFRKRIRDEDQASRIISHIRRARSLHIMCHIPVFCWISATVLQTILRQDLSAEIPQTLTEMYIHFLLIQTHMRKQKYEERDPEKLLRFNRDVIVKLAELAFNQLMKGNVMFYEEDLIESRIDVADASVYSGICTEIFREESVIYQRKVYSFVHLSFQECFAALYVFYCYLHNNTEVMKMFLTEIYRTQSKKVSLDVLLKGVMIEALKSKTGHLDLFLRFLHGVSLESNQRLLQDLLKHTENDPDSIKKIIKNLKRGQKNNVSPERWMNLSHCLMEMKDNSVVKEMQAFLKSKTQRKCLSLAQCSTLANMILMSEEVLDELDIKKYNIKSKEGRWRLIPAVRNCRKALLSECNLADQHCETVASALQSSNNLLREVNLSRNELQDSGVKLICAGLKSPNCQLNVLKLSGCNLTKQSCETVAVSLLSSNCRLRELDLSRNDLQDSGVKLICAGLKSANCQLNTLRLAKCNLTDQCCETISSFLQSSNSVLRELDISNNRLQDSGVKLIFTAIKSENCQLNILRLSSCNLTDQCCETLASSLQSSNCVLRELDLSNNELQDSGVKLICAGLKSPNCQLNTLRLSYCMVTEEGCAALASALSSTSSHLRELDLSYNHPGEAGLKLLSDKLKHLHKLNLGHGGEFRTISTLHKYACKLTLDPNTAHKHLVLSEENRKATRAFKDQSFPSHPERFDKLNLQVVSKESLTGRCYWETQWSGYAEISVCYKGIKRKGWSDDCEFGRNDQSWSLHCSDHSFSVCHNDERTHISVPPTFSGTVGVFVDESSGSLSFYSVSDKLTHLHTFNTTFTDTLHAGFRLFSNSSVSLCHI", "length": 1489, "header": "tr|F1Q5P9-1|F1Q5P9_DANRE Isoform 1 of Uncharacterized protein si:ch211-214b16.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-214b16.3 PE=4 SV=2 CANONICAL=F1Q5P9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:564346", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564346", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "F1Q5P9", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1Q5P9", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1041, "end_pos": 1043, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1075, "end_pos": 1077, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1133, "end_pos": 1135, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1191, "end_pos": 1193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1465, "end_pos": 1467, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1481, "end_pos": 1483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" }, { "start_pos": 837, "end_pos": 839, "annotation": "n_glycosylation_sequon" }, { "start_pos": 925, "end_pos": 927, "annotation": "n_glycosylation_sequon" }, { "start_pos": 933, "end_pos": 935, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1Q5P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 1298, "end_pos": 1489, "start_aa": "Asn", "end_aa": "Ile", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1Q5P9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5P9" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 506, "end_pos": 640, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1041, "end_pos": 1043 }, { "start_pos": 1075, "end_pos": 1077 }, { "start_pos": 1133, "end_pos": 1135 }, { "start_pos": 1191, "end_pos": 1193 }, { "start_pos": 1465, "end_pos": 1467 }, { "start_pos": 1481, "end_pos": 1483 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 223, "end_pos": 225 }, { "start_pos": 296, "end_pos": 298 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 438, "end_pos": 440 }, { "start_pos": 77, "end_pos": 79 }, { "start_pos": 837, "end_pos": 839 }, { "start_pos": 925, "end_pos": 927 }, { "start_pos": 933, "end_pos": 935 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0UYS3-1", "uniprot_ac": "B0UYS3", "uniprot_id": "B0UYS3_DANRE", "mass": { "chemical_mass": 132265.0, "monoisotopic_mass": 132265.0 }, "refseq": { "ac": "XP_001336777", "name": "DNA helicase B isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001336777" }, "gene_names": [ { "name": "helb", "type": "recommended", "evidence": [ { "id": "B0UYS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UYS3" } ] }, { "name": "helb", "type": "synonym", "evidence": [ { "id": "XP_001336777", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001336777" } ] } ], "protein_names": [ { "name": "DNA helicase B", "type": "recommended", "evidence": [ { "id": "B0UYS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UYS3/entry#names_and_taxonomy" } ] }, { "name": "3.6.4.12", "type": "synonym", "evidence": [ { "id": "B0UYS3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UYS3/entry#names_and_taxonomy" } ] }, { "name": "DNA helicase B isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001336777", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001336777" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001336777.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001336777", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001336777" } ] }, { "annotation": "5'-3' DNA helicase involved in DNA damage response by acting as an inhibitor of DNA end resection. Recruitment to single-stranded DNA (ssDNA) following DNA damage leads to inhibit the nucleases catalyzing resection, such as EXO1, BLM and DNA2, possibly via the 5'-3' ssDNA translocase activity of HELB. As cells approach S phase, DNA end resection is promoted by the nuclear export of HELB following phosphorylation. Acts independently of TP53BP1. Unwinds duplex DNA with 5'-3' polarity. Has single-strand DNA-dependent ATPase and DNA helicase activities. Prefers ATP and dATP as substrates. During S phase, may facilitate cellular recovery from replication stress.", "evidence": [ { "database": "UniProtKB", "id": "B0UYS3", "url": "https://www.uniprot.org/uniprotkb/B0UYS3#function" }, { "database": "UniProtKB", "id": "ARBA00055511", "url": "https://www.uniprot.org/uniprotkb/ARBA00055511#function" }, { "database": "UniProtKB", "id": "A0AB32TQK8", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQK8#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0UYS3", "url": "https://www.uniprot.org/uniprotkb/B0UYS3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "helb", "url": "https://www.uniprot.org/uniprotkb/B0UYS3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030729-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030729-16", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000053127", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000053127", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17933", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17933", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18809", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18809", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "797342", "url": "https://www.ncbi.nlm.nih.gov/gene/797342", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058839", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058839", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:797342", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797342", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KIKHAWA", "url": "https://omabrowser.org/oma/group/KIKHAWA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0UYS3", "url": "https://www.orthodb.org/?gene=B0UYS3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43788", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43788", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43788:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43788:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13538", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13538", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001336777", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001336777", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TQK8", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TQK8-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TQK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0UYS3", "url": "https://www.uniprot.org/uniprotkb/B0UYS3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0UYS3-1", "url": "https://www.uniprot.org/uniprotkb/B0UYS3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030729-16", "url": "https://zfin.org/ZDB-GENE-030729-16", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MALQSPIAGLKTITGYILPEEQAVQPNKDDGLESEDEEEEGQPEFLDMKEMNSVSSGGNMFKSLVPTSKEVSILVGKKTYKVEGRFPLCDPWWEVTCTIRLGRLKAFVKGYPFYRLRTHLKSEGRSLLSLFLTACKAQADHVKMFMDWLPTDRRVELVNVLDVLQEFEDSSLEHEAVAQQLKSSVNCSVVWTHVKAASLYPGIMKYLPTLLPGQYLDIIKRARIEDIPETSAMDEDPQNEQRKTNVLSKLEELINTNNVWKLGFNYIMFKELHLIRCEAKLEAFKLCDLFSAIPLLQRNALILYAELKKHCRVTGSTYITQEMLVDKIFSETGADGAWAALHFLVTQGVLMKESTKVALRNLLKYEKGIAECLTGLVQGDPWKIHLDVKEVLREAQIKRLRAKACEKHNATMKSKDDANTSASAAENSTAVFEQLGIDLDQPGTSSMVHNGETPSCDDSENTTLTIKEENLTSDSDSDLDIDPSTIELDCDQVRAAEMMCANPVTVISGKGGCGKTTVVSLVFKAAMEQQTSDLEEVQKACEDFQNDSHGSSNGLALDVHEEKNHSEKSISNEKSVEVLLTAPTGRAASLLTKRTGFTAYTMHQVLWSFMTVDKDRSGNPQDWKFSKVRVLVVDEGSLVSVQILHSILSMLTKHAQLQKFIILGDVRQLPSIEPGNTLYDLFEGLRRVRWAIEMRTNHRAESELIVRNAGLISEMGKKKYYKPLDFDATIDMTNPSAVPSDKRFIFIKISSDNFSFDLQEAILFLLKEAPGLKDHILSQFVAFRRKDCELINELCCRHYSNHTTKTAKKTFNFQVGDKVCCTKNGYVTDYDKKETSLADIRASHNRAESQQDDQKKEKKEKKERLCNGEIFFIKDDVTKSVENEKNKMVRQLTLDDKSDRQVTCNYKELQRECKLRHSWARTIHTFQGSEAETIVYILGDSPAQNWQHVYTAVTRGQKRVYVVGTEYDLEGAIRKRITPRNTRLCGFVNTKVGQQDPLTTSASTQRQAETTLNHSFGHSQSTPVASQTPIRPQMLSSTRPSCARNLYTDKNGEGDQTSNISLQDDMAFSQAYSWSPMDSCDEAGRVQNENMTELSNHVDDALLATLSSSPNESSRGSKRTIAEDIYSTPSKLPKQTASEESPMVSSRLNLLSLSSPDIKSSRQLFQDDTHSHRGQP", "length": 1176, "header": "tr|B0UYS3-1|B0UYS3_DANRE Isoform 1 of DNA helicase B OS=Danio rerio OX=7955 GN=helb PE=1 SV=1 CANONICAL=B0UYS3-1" }, "isoforms": [ { "isoform_ac": "A0AB32TQK8-1", "url": "https://www.uniprot.org/uniprotkb/B0UYS3/entry#A0AB32TQK8-1", "sequence": { "sequence": "MKYLPTLLPGQYLDIIKRARIEDIPETSAMDEDPQNEQRKTNVLSKLEELINTNNVWKLGFNYIMFKELHLIRCEAKLEAFKLCDLFSAIPLLQRNALILYAELKKHCRVTGSTYITQEMLVDKIFSETGADGAWAALHFLVTQGVLMKESTKVALRNLLKYEKGIAECLTGLVQGDPWKIHLDVKEVLREAQIKRLRAKACEKHNATMKSKDDANTSASAAENSTAVFEQLGIDLDQPGTSSMVHNGETPSCDDSENTTLTIKEENLTSDSDSDLDIDPSTIELDCDQVRAAEMMCANPVTVISGKGGCGKTTVVSLVFKAAMEQQTSDLEEVQKACEDFQNDSHGSSNGLALDVHEEKNHSEKSISNEKSVEVLLTAPTGRAASLLTKRTGFTAYTMHQVLWSFMTVDKDRSGNPQDWKFSKVRVLVVDEGSLVSVQILHSILSMLTKHAQLQKFIILGDVRQLPSIEPGNTLYDLFEGLRRVRWAIEMRTNHRAESELIVRNAGLISEMGKKKYYKPLDFDATIDMTNPSAVPSDKRFIFIKISSDNFSFDLQEAILFLLKEAPGLKDHILSQFVAFRRKDCELINELCCRHYSNHTTKTAKKTFNFQVGDKVCCTKNGYVTDYDKKETSLADIRASHNRAESQQDDQKKEKKEKKERLCNGEIFFIKDDVTKSVENEKNKMVRQLTLDDKSDRQVTCNYKELQRECKLRHSWARTIHTFQGSEAETIVYILGDSPAQNWQHVYTAVTRGQKRVYVVGTEYDLEGAIRKRITPRNTRLCGFVNTKVGQQDPLTTSASTQRQAETTLNHSFGHSQSTPVASQTPIRPQMLSSTRPSCARNLYTDKNGEGDQTSNISLQDDMAFSQAYSWSPMDSCDEAGRVQNENMTELSNHVDDALLATLSSSPNESSRGSKRTIAEDIYSTPSKLPKQTASEESPMVSSRLNLLSLSSPDIKSSRQLFQDDTHSHRGQP", "length": 973, "header": "tr|A0AB32TQK8-1|B0UYS3_DANRE Computationally mapped isoform of DNA helicase B OS=Danio rerio OX=7955 GN=helb PE=1 SV=1 CANONICAL=B0UYS3-1" }, "locus": {} }, { "isoform_ac": "B0UYS3-1", "url": "https://www.uniprot.org/uniprotkb/B0UYS3/entry#B0UYS3-1", "sequence": { "sequence": "MALQSPIAGLKTITGYILPEEQAVQPNKDDGLESEDEEEEGQPEFLDMKEMNSVSSGGNMFKSLVPTSKEVSILVGKKTYKVEGRFPLCDPWWEVTCTIRLGRLKAFVKGYPFYRLRTHLKSEGRSLLSLFLTACKAQADHVKMFMDWLPTDRRVELVNVLDVLQEFEDSSLEHEAVAQQLKSSVNCSVVWTHVKAASLYPGIMKYLPTLLPGQYLDIIKRARIEDIPETSAMDEDPQNEQRKTNVLSKLEELINTNNVWKLGFNYIMFKELHLIRCEAKLEAFKLCDLFSAIPLLQRNALILYAELKKHCRVTGSTYITQEMLVDKIFSETGADGAWAALHFLVTQGVLMKESTKVALRNLLKYEKGIAECLTGLVQGDPWKIHLDVKEVLREAQIKRLRAKACEKHNATMKSKDDANTSASAAENSTAVFEQLGIDLDQPGTSSMVHNGETPSCDDSENTTLTIKEENLTSDSDSDLDIDPSTIELDCDQVRAAEMMCANPVTVISGKGGCGKTTVVSLVFKAAMEQQTSDLEEVQKACEDFQNDSHGSSNGLALDVHEEKNHSEKSISNEKSVEVLLTAPTGRAASLLTKRTGFTAYTMHQVLWSFMTVDKDRSGNPQDWKFSKVRVLVVDEGSLVSVQILHSILSMLTKHAQLQKFIILGDVRQLPSIEPGNTLYDLFEGLRRVRWAIEMRTNHRAESELIVRNAGLISEMGKKKYYKPLDFDATIDMTNPSAVPSDKRFIFIKISSDNFSFDLQEAILFLLKEAPGLKDHILSQFVAFRRKDCELINELCCRHYSNHTTKTAKKTFNFQVGDKVCCTKNGYVTDYDKKETSLADIRASHNRAESQQDDQKKEKKEKKERLCNGEIFFIKDDVTKSVENEKNKMVRQLTLDDKSDRQVTCNYKELQRECKLRHSWARTIHTFQGSEAETIVYILGDSPAQNWQHVYTAVTRGQKRVYVVGTEYDLEGAIRKRITPRNTRLCGFVNTKVGQQDPLTTSASTQRQAETTLNHSFGHSQSTPVASQTPIRPQMLSSTRPSCARNLYTDKNGEGDQTSNISLQDDMAFSQAYSWSPMDSCDEAGRVQNENMTELSNHVDDALLATLSSSPNESSRGSKRTIAEDIYSTPSKLPKQTASEESPMVSSRLNLLSLSSPDIKSSRQLFQDDTHSHRGQP", "length": 1176, "header": "tr|B0UYS3-1|B0UYS3_DANRE Isoform 1 of DNA helicase B OS=Danio rerio OX=7955 GN=helb PE=1 SV=1 CANONICAL=B0UYS3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 954, "start_aa": "Thr", "end_pos": 954, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr954", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme", "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:797342", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797342", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YG75-1", "protein_name": "DNA helicase B", "gene_name": "HELB", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGTGRGAAAELWGVLLPPRRAAEGSEDEEDEEVEEEPHLAEAALLEASGRDLTAALPPRRAAVIQESSKKEYEVVGRFPLVGPWWTVNVKVKKGGSKYFVQGYPSYFLRTDIEDNNREIFSLFLKECGVPEYFKKLFFAWLPAKSTLSFGNLEEKLKQFQVSHLSTGKKQGDTKDFNISYYVWKSVAGKAVLVALTYPMILEFLPTLLPRHFCSLLDTVCWQRKTESADTDGETVHFEDEILTKLDEILKNEPWKLGFSRITYRELKLSYCEATWDAFRQCEHLLWKIPDLQKNALILYNKLKKHCREMGHTYENQDELTRFVSEDMSIESAWQSLEFLKDENIVIREKTLVFLPHLYKSEKDIAMYIGDLLSKCSWQLDVDARKILTASEMSREVVDSKTNGIQAQEVEHLKEDNPHNHHCENQFPEREVASTSGTQSKAEVDPDQVIAIEKICSNPVTIISGKGGCGKSTIVSCLFRHLKQIEKEVEAASKDFEEDLDVSEEWDTFDRHWESENTCTKNPLNVLFTAPTGRAASLLSEKTNLPAYTLHQIIYSFKSWRQTEKEVPWKFSTVTVLIVDEGSLVSVHILSLVLKILCEHAQLAKLIILGDTRQLPSIDPGNMLADIFNSLKSKGLSVELRTNHRAESQLIVDNATRISLRKLPEFDEVLKFSGWNKELAMPSPEKKFIFIALPSNGGADNLQAAIKALLKEGPGLQDATQSQFIAFRRQDCDLINELCCQHYSNHLTRDHKRRLLFQVDDKISCTRNMYLKDLLPDPGIGRDPEQHKCRNGETTLSTENTEEGKRLCNGDIFFITRDVEINKQRLLTISSTYGSTYTVNYKALKKLCHIKHAWARTIHTFQGSEEKTVVYVVGNPGRQHWQHVYTAVTRGRCRVYVIAEEMHLRKAVTNNNFPRKTRLQRFLREAIANTNSCLTQTSSPLTKSWPGQERGTQPVSLTRDVPDPSQPGTDRIQQEGSADLNKEHTGHLQQISPYKRQQSHAEDSENPLGKDSPLGTARLRSLTLEQVTPRKLFKS", "length": 1035 }, "evidence": [ { "id": "B0UYS3", "url": "https://omabrowser.org/oma/group/B0UYS3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D4AAN8-1", "protein_name": "DNA helicase B", "gene_name": "Helb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGQGVLRELLGPLNPYKSDDEEEDCAQEEGEQDSEFVDAEELCSGGIKAGSLPGRMRVSIPDENTKEKCTVYGRFPLKDPWWRVRVRVVKHAQSSKSYQVQGFPSYFLQSDMSPPDQKSICSLFLKECNFTPERIQEFLKWVDKVSSFENLNFENLRETFRNFCRETTKKDKMQSTQSDQGDEQKLEKSFPFVIAMTALQFPKVMEFLPTLFPRHFKSLISSCSETVLGHIEEALGTQPWKLGFRRITYREMKLLSCEASWTSFSQCPSLLQLMTALQKNALVLYSKLRQTCREDGHTYIKVKDLTWGLSEHMSFEEACQSLDFLRTIDVITYEKDFIFLSELYQAEHDIASFICELMNRPPWHLKVDVRNVLASIGGAKSTDSGSTEAVEGSKPDEVEVEVAAEQGDSVLGAQDSGDHVRSNGEHVTSAEINRVPLDRDQVVALETICTNAVTVLSGKGGCGKTTIVSRLFKHVEQLEEREVQQACEDFEQDQGASEEWLDFPKQSPAGVDKAIEVLLTAPTGKAAGLLRQKTHLPAYTLCQVNYSFYMWKKNEADKPWKFSTVRVLVVDEGSLVSVAIFKSVLKLLREHSKLSKLVILGDVRQLPSIEPGNMLQDVFETLKSRQCAIELKTNHRTESQLIVDNAARISRRQFPEFDAEINISDNSTLPNSIQDKTFIFVRLPEEDSSSQSSKGKHQADLYSAVKTLLQGKDFCSPESAKTSQFIAFRRQDCDLINDCCSKHYTDHLIKDHKKKLIFAVGDKICCTRNAYLSDLLPDRDQEANGKGFGDAPDDNAKGKQDFESSIRLCNGEIFFITRDVTDVTSKRKRLLTISNDAGLEVTVDFNKLMTNCQIKHAWARTIHTFQGSEEKTVAYVVGKAGRQHWQHVYTAVTRGRSRVYIIAEESELRSAIRKRSFPRQTRLKHFLQKKLSSSCASSEGLPSQPSSPRVGGRPDTQPLASPLCTTPGSKATANSARGEASPATKERFALDGRWLSTCFSDMDTDEESEQLRGSKRTGDGFPFEEESPSKFRMVEESSPQVSSIFQSLRLNNLTRRQLFKPSDNQETAKSGVVDHTNNASNQETEP", "length": 1087 }, "evidence": [ { "id": "HGNC:17196", "url": "https://alliancegenome.org/gene/HGNC:17196#orthology", "database": "AGR" }, { "id": "MGI:2152895", "url": "https://alliancegenome.org/gene/MGI:2152895#orthology", "database": "AGR" }, { "id": "B0UYS3", "url": "https://omabrowser.org/oma/group/B0UYS3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GY12-1", "protein_name": "DNA helicase B", "gene_name": "Helb", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAGECLLRELLGPLHPNKDDKEEECVQEDEGDQDSEFVDAEELCSGGIRAGSLPGRIRVSIPDENTKERCTVQGRFPLIGPWWRVKVRVVKPERSKVYQAQGFPSYFLQSDMSPPHRKTILLLFLKECNYERRNEFLKWVEKVSGYENLNFENLRETLRNFDRETGKESKKQFTQSEWDEMRLPVEKSFPFVSVMTALQFPKVMEFLPVLLPRHFRKLISSSSEEVLQKIEEALGTHPWKLGFRRVTYREMKLLSCEASWMSFRQCPSLLQLMTEQQRNALILYSTLRQTCREDGHTYVDVKEFTSSVSEYMSFQQACGSLEFMKDLDVVTYEKDCIFLSELYEAEQGIASTICDLMNRPPWHLQVDVKNVLASICKGEPKDSGSAEAVGRSEPDKVGLEQGESVSDPQDRGDHVRNNGGHEMDAEINDVPLDPDQVAALEMICANAVTVLSGKGGCGKTTIVSHLFKHVEQLEEREVQQACEDFEQDQDASEEWLAFSEQSPAAVDKAAQVLLTAPTGKAAALLWQRTHLLAYTLYQVNYSFYFWKKHNGEEPWKFSTVRVLVVDEGSLVSVGIFKSVLKILCEHTKLSKLVILGDIRQLPSIEPGNMLQDVFETLKSRGCAIELKTNHRAESQLIVDNATRISRRQFPEFDAVLNISDNPTLPISIQDKTFIFVRLPEGEHQSNLYSAVTTLLQGKDFESAKTSQFIAFRRQDCDLINDCCSKHYTGHLIKDHKKKLVFSVGDKICCTRNAYLSDLLPDEDEEAIRKGFDLVLSDDAPSDAATPSDIKIKKNFESDIRLCNGEIFFITRDVTDVTFKTKRLLTINNEAGLEVTVDFSKLMTNCQIKHAWARTIHTFQGSEENIVAYVVGKAGRQHWQHVYTAVTRGRSRVYVIAEESELRNAIRKRSFPRKTRLKHFLQKQLLSSARASPTGFLSQPSSPRAAERPSTQPLASPFCRTPDKRATTNSPGGEVSSATKETFALDKGWLSTSFSDIDTDEESAQPRGSKRTGSGFPFDEESPSKFCLVEKPSPQVSSIFQNLRLNNRARRQLFKPTDNQEMIKSDVVGHTNDPSNQEADTGGS", "length": 1083 }, "evidence": [ { "id": "B0UYS3", "url": "https://omabrowser.org/oma/group/B0UYS3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6NVF4-1", "protein_name": "DNA helicase B", "gene_name": "Helb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARQDRLRELLGPLHPYKSDDEEEDCAQEEEGEQEEEFVDAEELCSGGIKAGSLPGRARVSIPDEYTKEKCTVYGRFPLKGPWWRVKVQVLKPQRSRSYQVQGFPAYFLQVDMSPPDQKQICSLFLKECNLASERIQEFLKWVEKVSSFENLHFENLWETLRLFYRETEKKDKKLSTPREQQGEEMRVEKSFAFISAMVALQFPKVMEFLPSLFPRHFKRLISSSSDWVLGCIEDVLGTQPWKLGFRRITYREMKLVRCEASWTAFSQCPSLLQLMTPLQKNALVIYSKLRQTCREDGHTYIEVKDLTSGLSEHMSFEEACQSLAFLKDIDVVIYEKDYVFLSELYEAEQDIASSICELMSRPPWHLKVDVKNVLASIRGAKPNDPGSAEAVEGSKPEEVGSEQGDSVLDAQDGDDHVRSNGEHVANAEINDVPLDQDQVVALETICANAVTVLSGKGGCGKTTIVSRLFKHMEHLEETEVQQACEDFEQDQEASEEWLDCPKQSPAGVDKAVEVLLTAPTGKAAGLLRQRTDLPAYTLCQVNYSFYMWKTKNEVDKPWKFSTVRVLVVDEGSLVSVGIFKSVLQLLCKHSKLSKLIILGDVRQLPSIEPGNMLQDVFETLKSRQCAIELKTNHRTESQLIVDNATRISRRQFPKFDAELNICGNPTLPLSIQDKTFIFVRLPEEDSRSQSSKGEHRSNLYTAVKTLLQGKDFCSFESSKTSQFIAFRRQDCDLINDCCCKHYTGHLIKDHEKKLIFAVGDKICCTRNAYLSDLLPDKDQEAEGKGYGDAPDDDAKIKQDFESSTRLCNGEIFFITRDVTDVTFKRKRLLTINNEAGLEVTVDFSKLMANCQIKHAWARTIHTFQGSEENTVVYVVGKAGRQHWQHVYTAVTRGRSRVYIIAQESELRSATRKRGFPRQTRLKHFLQKKLSGSCAPSTGFASQPSSPRVGGRPDTQPPASHLCRTPDNKATADSARGDERWLSASVNDDVDTDEESAQLRGSKRIGDGFPFDEESPSKFRMVEAPSPQVSSVFQNMRLNTLTPRQLFKPTDNQDTGTAGVADDANDPSNQEMEM", "length": 1074 }, "evidence": [ { "id": "HGNC:17196", "url": "https://alliancegenome.org/gene/HGNC:17196#orthology", "database": "AGR" }, { "id": "MGI:2152895", "url": "https://alliancegenome.org/gene/MGI:2152895#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030729-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030729-16#orthology", "database": "AGR" }, { "id": "B0UYS3", "url": "https://omabrowser.org/oma/group/B0UYS3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NG08-1", "protein_name": "DNA helicase B", "gene_name": "HELB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARSSPYLRQLQGPLLPPRDLVEEDDDYLNDDVEEDEESVFIDAEELCSGGVKAGSLPGCLRVSICDENTQETCKVFGRFPITGAWWRVKVQVKPVVGSRSYQYQVQGFPSYFLQSDMSPPNQKHICALFLKECEVSSDDVNKFLTWVKEVSNYKNLNFENLRETLRTFHKETGRKDQKQPTQNGQEELFLDNEMSLPLENTIPFRNVMTALQFPKIMEFLPVLLPRHFKWIIGSGSKEMLKEIEEILGTHPWKLGFSKITYREWKLLRCEASWIAFCQCESLLQLMTDLEKNALIMYSRLKQICREDGHTYVEVNDLTLTLSNHMSFHAASESLKFLKDIGVVTYEKSCVFPYDLYHAERAIAFSICDLMKKPPWHLCVDVEKVLASIHTTKPENSSDDALNESKPDEVRLENPVDVVDTQDNGDHIWTNGENEINAEISEVQLDQDQVEVPLDRDQVAALEMICSNPVTVISGKGGCGKTTIVSRLFKHIEQLEEREVKKACEDFEQDQNASEEWITFTEQSQLEADKAIEVLLTAPTGKAAGLLRQKTGLHAYTLCQVNYSFYSWTQTMMTTNKPWKFSSVRVLVVDEGSLVSVGIFKSVLNLLCEHSKLSKLIILGDIRQLPSIEPGNLLKDLFETLKSRNCAIELKTNHRAESQLIVDNATRISRRQFPKFDAELNISDNPTLPISIQDKTFIFVRLPEEDASSQSSKTNHHSCLYSAVKTLLQENNLQNAKTSQFIAFRRQDCDLINDCCCKHYTGHLTKDHQSRLVFGIGDKICCTRNAYLSDLLPENISGSQQNNDLDASSEDFSGTLPDFAKNKRDFESNVRLCNGEIFFITNDVTDVTFGKRRSLTINNMAGLEVTVDFKKLMKYCRIKHAWARTIHTFQGSEEQTVVYVVGKAGRQHWQHVYTAVTRGRCRVYVIAEESQLRNAIMKNSFPRKTRLKHFLQSKLSSSGAPPADFPSPRKSSGDSGGPSTPSASPLPVVTDHAMTNDVTWSEASSPDERTLTFAERWQLSSPDGVDTDDDLPKSRASKRTCGVNDDESPSKIFMVGESPQVSSRLQNLRLNNLIPRQLFKPTDNQET", "length": 1087 }, "evidence": [ { "id": "HGNC:17196", "url": "https://alliancegenome.org/gene/HGNC:17196#orthology", "database": "AGR" }, { "id": "MGI:2152895", "url": "https://alliancegenome.org/gene/MGI:2152895#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030729-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030729-16#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "negative regulation of double-strand break repair via homologous recombination", "id": "GO:2000042", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2000042", "evidence": [ { "database": "UniProtKB", "id": "B0UYS3", "url": "https://www.uniprot.org/uniprotkb/B0UYS3" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "B0UYS3", "url": 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Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005168698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168698" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q786", "url": "https://www.uniprot.org/uniprotkb/F1Q786" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ttf1.6", "url": "https://www.uniprot.org/uniprotkb/F1Q786", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041008-214", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041008-214", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000094107", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000094107", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "449954", "url": "https://www.ncbi.nlm.nih.gov/gene/449954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053078", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053078", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:449954", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449954", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHIRRKC", "url": "https://omabrowser.org/oma/group/PHIRRKC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1Q786", "url": "https://www.orthodb.org/?gene=F1Q786", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46760", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46760", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46760:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46760:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13921", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13921", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-5683826", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5683826", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-73863", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-73863", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005168698", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005168698", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TUG7", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TUG7-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TUG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q786", "url": "https://www.uniprot.org/uniprotkb/F1Q786", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q786-1", "url": "https://www.uniprot.org/uniprotkb/F1Q786-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041008-214", "url": "https://zfin.org/ZDB-GENE-041008-214", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDEMPSLSSNARVDGEKVKKKRSKPTEQHELTESPQEQAEKRLKKKEKMRNSIRETDINLQIKKRRKLDDEGETPVLDDGVSNQHEAQTQELQGSREGKTSKRKKMREKLKQTNCEDMAKQQTDIRREHEDEPNTSDHERGLLDIMMGTKTRKTKQLLSDEPLVDLNALDELNQFCPKITLASRSARDINKMIRIDLPRFKEFRKQGIELRHGRFSTAENERLRQNVSNFLALTGVKDAIKLFHPKRFPKESQTLANLKRKYSFFVKIAEGIPRPCHDVYTRGTKIYDDRNKKGNFTEEEEKSLLKYYTLYGPDWKKISDKTDRSSYSLEKRFSHLSKIRGPWTTNEVQRLLRAVRDHVVSVLKSANPKKKKPKRVSREILYQALPWSKIAEKVKTRCWTKCRDKWMSILASRMSSGITFRGRKAQEAKIKLIRAMYEMQVEDVVDVDWEHLTAVFGDVPPAYAQSRWHQLKVCYVPDWQNKCFGDIVDFLYENTLPGLVKECKDLDDDELTVDQMNSFRLADIFQDINEDECCDDDEQTGQQENNHSS", "length": 549, "header": "tr|F1Q786-1|F1Q786_DANRE Isoform 1 of Transcription termination factor 1 isoform X1 OS=Danio rerio OX=7955 GN=ttf1.6 PE=1 SV=2 CANONICAL=F1Q786-1" }, "isoforms": [ { "isoform_ac": "A0AB32TUG7-1", "url": "https://www.uniprot.org/uniprotkb/F1Q786/entry#A0AB32TUG7-1", "sequence": { "sequence": "MDEMPSLSSNARVDGEKVKKKRSKPTEQHELTESPQEQAEKRLKKKEKMRNSIRETDINLQIKKRRKLDDEGETPVLDDGVSNQHEAQTQELQGSREGKTSKRKKMREKLKQTNCEDMAKQQTDIRREHEDEPNTSDHERGLLDIMMGTKTRKTKQLLSDEPLVDLNALDELNQFCPKITLASRSARDINKMIRIDLPRFKEFRKQGIELRHGRFSTAENERLRQNVSNFLALTGVKDAIKLFHPKRFPKESQTLANLKRKYSFFVKIAEGIPRPCHDVYTRGTKIYDDRNKKGNFTEEEEKSLLKYYTLYGPDWKKISDKTDRSSYSLEKRFSHLSKIRGPWTTNEVQRLLRAVRDHVVSVLKSANPKKKKPKRVSREILYQALPWSKIAEKVKTRCWTKCRDKWMSILASRMSSGITFRGRKAQEAKIKLIRAMYEMQVEDVVDVDWEHLTAVFGHC", "length": 459, "header": "tr|A0AB32TUG7-1|F1Q786_DANRE Computationally mapped isoform of Transcription termination factor 1 isoform X1 OS=Danio rerio OX=7955 GN=ttf1.6 PE=1 SV=1 CANONICAL=F1Q786-1" }, "locus": {} }, { "isoform_ac": "F1Q786-1", "url": "https://www.uniprot.org/uniprotkb/F1Q786/entry#F1Q786-1", "sequence": { "sequence": "MDEMPSLSSNARVDGEKVKKKRSKPTEQHELTESPQEQAEKRLKKKEKMRNSIRETDINLQIKKRRKLDDEGETPVLDDGVSNQHEAQTQELQGSREGKTSKRKKMREKLKQTNCEDMAKQQTDIRREHEDEPNTSDHERGLLDIMMGTKTRKTKQLLSDEPLVDLNALDELNQFCPKITLASRSARDINKMIRIDLPRFKEFRKQGIELRHGRFSTAENERLRQNVSNFLALTGVKDAIKLFHPKRFPKESQTLANLKRKYSFFVKIAEGIPRPCHDVYTRGTKIYDDRNKKGNFTEEEEKSLLKYYTLYGPDWKKISDKTDRSSYSLEKRFSHLSKIRGPWTTNEVQRLLRAVRDHVVSVLKSANPKKKKPKRVSREILYQALPWSKIAEKVKTRCWTKCRDKWMSILASRMSSGITFRGRKAQEAKIKLIRAMYEMQVEDVVDVDWEHLTAVFGDVPPAYAQSRWHQLKVCYVPDWQNKCFGDIVDFLYENTLPGLVKECKDLDDDELTVDQMNSFRLADIFQDINEDECCDDDEQTGQQENNHSS", "length": 549, "header": "tr|F1Q786-1|F1Q786_DANRE Isoform 1 of Transcription termination factor 1 isoform X1 OS=Danio rerio OX=7955 GN=ttf1.6 PE=1 SV=2 CANONICAL=F1Q786-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:449954", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:449954", "resource": "KEGG Pathway" }, { "id": "R-DRE-5683826", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5683826", "resource": "Reactome", "description": "Surfactant metabolism" }, { "id": "R-DRE-73863", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-73863", "resource": "Reactome", "description": "RNA Polymerase I Transcription Termination" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286YBY6-1", "protein_name": "Transcription termination factor 1", "gene_name": "ttf1.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDEMPSLSSNDCNDRVGGKKVKKKKKRSKSTEQHELTESPQEQTEKRRKKKKRRNSIQETDSNLQTKKRRKLDKEGETSVMDDGVSNQHEEQTQELQGSREGKTSKRKKKREKLKQTQELQGSREGKTSKRKKKREKLKQTNCEDITKEQTDIRTEHEEEPNTSDPPDLIITDKKRESKTPKNNIDSKFMEELNEWVPKMKLRCKSYMNDIIRYELSRFKEFRKQGIEMRTGRFSTAENERLRQNVNNFMALTGVTDAVKLFFPSRYPKEANALRKLKKKHRFFESIADGIPRFCNDVYDRGARVYDDRNYKGHFSEEEVKLLLKYYKRYGRDFKKISDKTNRSCRSLESRLLFITERKGPWSSKEVQRLLRAVRDYVVSVLKSANPNQRKPKRVNKEILYKKLPWTKIAGQVKTRCWMTCKSKWMTILTARMSSGTTFRGRKSQEAKIKLIKAMYELQVEDAVDVPWEDLTAVFGDVLPSYVQSRWHKLKVNHVPDWKNKSFADIVDFLYENVLPGLVKDCEDLDDDELKVDQMNSFRLADIFQDINEDECCDSDEETGQQEKSSSA", "length": 568 }, "evidence": [ { "id": "MGI:105044", "url": "https://alliancegenome.org/gene/MGI:105044#orthology", "database": "AGR" }, { "id": "HGNC:12397", "url": "https://alliancegenome.org/gene/HGNC:12397#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M3B2X7-1", "protein_name": "Transcription termination factor 1.2", "gene_name": "ttf1.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDEMQSDSPNNVDGEKMKKKKISKTTEQHELTESPQEQTEKRRKKKKKKRRDSTTECDDDLQTDTGKKKKRRKLDNEGETSVMDDGVSDQHEAQTQELPGSSEEKTSRRLKARVSATQTSHAEMTEEEQTDTETEHEEEPNTSDDEESGPPDVVIGTGWRKSRKIPVDLKLLAELKEFCPNTAIESQSDTEINKMIKYDLPRFREFKKQGIAMRHGRFSKAENEKLRQNVSDLLALTQLKDAVMLFHPKRFLNEEMKLAELKRMYGFYQKIAEGIPRPCHDVYTRGKKMFDHRHYKGNFTEEEDKRLLKYYNLYGPNWKKISEKTGRSSFSLRKRFPQISSVKRKGPWTPEEVQRLLRAVREHVLSVLKSANPNKKKPKRVRREILYENLPWTTIADKVETRCYRQCREKWMSILFTRMSSGTTFRGKAGLLAKIRLIKAMYEMQVEDVADIDWESLTAAFGNVPPAHVQKMWRKIKNYYLPDWNSRSFKDNVSHLHKNILPCLVSSCKGFDVNAVKVEQKELFRLSKIFKDIEEDGQDIEEDGQDIEEDGRDGDEETGEQENNSFN", "length": 567 }, "evidence": [ { "id": "MGI:105044", "url": "https://alliancegenome.org/gene/MGI:105044#orthology", "database": "AGR" }, { "id": "HGNC:12397", "url": "https://alliancegenome.org/gene/HGNC:12397#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13A7V5-1", "protein_name": "Transcription termination factor 1.1", "gene_name": "ttf1.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDEMLSDSPNNVDGEKVKKKRSKTTEQHELTESPQEQTEKRRKKKKKRRNSTTESKDNLQTDTGKKKRRKLDNEGETSVMDDGVSDQHEAQTQELPGSSEEKTSRRLRTRKTATQTSYAEMTEEEQTDTDTETEHEHEEAPNTSDEESDPLDAVTGDVTRTRKTRKIPVDLKLLAELKEFCPNTAIESRCDNDINKMIRYDLARFREFKKQGIALRQGRFSEAENERLRQNVSDLLALTKVKDAAMLFHPKQFPQAQMKLAKLKRKFGFYQKIAEGIPRPCQFVYIRGKKMFDHRHYKGNYTEEEDKRLLKYYKKYGPKWEKISEKTGRSSTSVCKRLPQISSVKRKGPWTPEEVQRLLKAVREHVLSVLKSANPNKKKPKRVRREILYENLPWTAIAAKVETRCYKTCREKWMSILSLRMSSGTTFRGKAGLLARIRLIKAMYELQVEDAADIDWGSLTVAFGNVPPAHVQKMWHKMKNYYVPDWNSRSFKDNVSHLHNDILPCLVRSCKGFDVNAVQVEQKELFRLSKIFKDIKEESQDIEEDGQDIEEDGQDIEEDGHDGDEETGEQENNSFNQ", "length": 577 }, "evidence": [ { "id": "MGI:105044", "url": "https://alliancegenome.org/gene/MGI:105044#orthology", "database": "AGR" }, { "id": "HGNC:12397", "url": "https://alliancegenome.org/gene/HGNC:12397#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D4A1Z7-1", "protein_name": "Transcription termination factor 1", "gene_name": "Ttf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRSKTEVSTVFPPHNTSGLKDECYTISGMEGGKFKTHTATLHKKKKWSSVSEKRLQKWPSQHLESEQPQVSVRKKRRRESQTPAQESLESEQPWKAKKKKKRRRESQTPAQESLESEQTPMSMLGKRRRESQTPAQENLESEQPWKAKKKKRRREYQTPAEESLESEQPWKAKRKKKKEKESQQLTSSLLKNSETFHKAKKTTAAHKKKKNSVWEVDMETGIILVDKENMENLLETSRKDVDIVYVDMSKGQRSAKVNETEELPMAETQKRDCRELHSDIRSKKNQKHPQKIAPQDAIQGTQPERISLPQSESLSPVDLEGKNTKIAVFCKKKSKKKVFRSQELEAVSESLVSSETIPESLDSAHHGGEDETEEEGESIKESHRIRKKSKKKKHKSVTLATSGDSVSVLDSTAESALVDSPEGSGTLREEDVDHGSTEAEAQARPTEKHRKEIQRLEPTHEESNLESASNSATRCVSEDRRDSDESDVDLGSAVRQLQEFIPDIQERAATTIRRMYRDDLGRFKEFKAQGVAIRFGKFSVKENKQIEKNVQDFLSLTGIESADKLLYTDRYPEEKSLITNLKRKHAFRLHIGKGIARPWKLVYYRAKKIFDVNNYKGRYNEEDTKKLKAYHSLHGNDWKKIGAMVARSSLSVALKFSQIDGDRNHGTWSKAETQRLIKAVEDVILKKMSSQELRELDSRLQEDPEGRLSIVREKLYKGISWVEVEARVETRNWMQCKSKWTEILTKRMTHGGFVYRGVKALQAKITLIERLYELNVNDANEIDWEDLAGAIGDVPPPFVQAKFYKLKAACVPFWQKKTFPEIIDYLYENSLPLLKEKLAKKMKKKDSQIQKPTAPKQNFLFKDIFHCDDDSDEGGLEEPSTSDTQ", "length": 885 }, "evidence": [ { "id": "MGI:105044", "url": "https://alliancegenome.org/gene/MGI:105044#orthology", "database": "AGR" }, { "id": "HGNC:12397", "url": "https://alliancegenome.org/gene/HGNC:12397#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12457-1", "protein_name": "RNA polymerase I termination factor", "gene_name": "NSI1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MDSVSNLKSTNFQNNNDPKESVEEAVLRYVGVDLKNHIKKTKKKLKKQKKRKHGSKMSHEDEDTDMDWYLKTSGSKDLRKVDDIEPNSVAVAAVAAAYNSSMREKDKRSCHKKSSNSRSERKKHRKRKSSKERKAKIKMVLDPQLTTLDDGITTTAFLPDDLIAETAFDKYVDTEKAYLAKHPSKSLEVNEDDKENNFNNNSSTLVRIYTDLEGIPNDGSYIKRTPKIPEKDVKSDDLILAPEENNGDTALLRSDIVKASVIDGAITKSIGKKFTPSEENALDQFIEEYMKIRGLDRRQMCERIWSTDGVIRDGFWANISKVLPYRTRSSIYKHIRRKYHIFEQRGKWTPEEDQELARLCLEKEGHWTEVGKLLGRMPEDCRDRWRNYMKCGSKRGSKRWSKEEEELLTTVVNEMIEEAHQYQRMKALEAANKNDRYNQMYSRGPKGKRISDNPTFKDMINWTVVSERMSGTRSRIQCRYKWNKLVTDEAARSMLSIPVSERKWLLERLKQLPKTSYSNIDWNSIATYKPGYPRTGLELRLCYEQMREKIHDFKGRSTAEIIDSLLEQIN", "length": 570 }, "evidence": [ { "id": "MGI:105044", "url": "https://alliancegenome.org/gene/MGI:105044#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q15361-1", "protein_name": "Transcription termination factor 1", "gene_name": "TTF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEGESSRFEIHTPVSDKKKKKCSIHKERPQKHSHEIFRDSSLVNEQSQITRRKKRKKDFQHLISSPLKKSRICDETANATSTLKKRKKRRYSALEVDEEAGVTVVLVDKENINNTPKHFRKDVDVVCVDMSIEQKLPRKPKTDKFQVLAKSHAHKSEALHSKVREKKNKKHQRKAASWESQRARDTLPQSESHQEESWLSVGPGGEITELPASAHKNKSKKKKKKSSNREYETLAMPEGSQAGREAGTDMQESQPTVGLDDETPQLLGPTHKKKSKKKKKKKSNHQEFEALAMPEGSQVGSEVGADMQESRPAVGLHGETAGIPAPAYKNKSKKKKKKSNHQEFEAVAMPESLESAYPEGSQVGSEVGTVEGSTALKGFKESNSTKKKSKKRKLTSVKRARVSGDDFSVPSKNSESTLFDSVEGDGAMMEEGVKSRPRQKKTQACLASKHVQEAPRLEPANEEHNVETAEDSEIRYLSADSGDADDSDADLGSAVKQLQEFIPNIKDRATSTIKRMYRDDLERFKEFKAQGVAIKFGKFSVKENKQLEKNVEDFLALTGIESADKLLYTDRYPEEKSVITNLKRRYSFRLHIGRNIARPWKLIYYRAKKMFDVNNYKGRYSEGDTEKLKMYHSLLGNDWKTIGEMVARSSLSVALKFSQISSQRNRGAWSKSETRKLIKAVEEVILKKMSPQELKEVDSKLQENPESCLSIVREKLYKGISWVEVEAKVQTRNWMQCKSKWTEILTKRMTNGRRIYYGMNALRAKVSLIERLYEINVEDTNEIDWEDLASAIGDVPPSYVQTKFSRLKAVYVPFWQKKTFPEIIDYLYETTLPLLKEKLEKMMEKKGTKIQTPAAPKQVFPFRDIFYYEDDSEGEDIEKESEGQAPCMAHACNSSTLGGQGRWII", "length": 905 }, "evidence": [ { "id": "MGI:105044", "url": "https://alliancegenome.org/gene/MGI:105044#orthology", "database": "AGR" }, { "id": "HGNC:12397", "url": "https://alliancegenome.org/gene/HGNC:12397#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041008-214", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041008-214#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q62187-1", "protein_name": "Transcription termination factor 1", "gene_name": "Ttf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGGTSKFKTHTETLYKKKKWSSVSEKRPQKCPSQCLESKQPQVSVLGKRRRASQTPAQETLESEWPQKAKRKKRRREPQTPAQETLESEWPQKAKKKKRRGEPQTPTQESLESEQPPVSLLGKRRRESQTPAQENSESEQPRKAKRRRKKRKGSQQPTSSLLKTPETFLKAKKTTSAHKKKKNSVLEVDMETGIILVDKENMENLLETSRKDVDIVYVDMSKGQRSAKVRETGELPAAKPQEHGCRELLGDVRSRKKQKHLQKVAPWDVVQGSQPESISLPPSEPLSSEDLEGKSTEAAVFCKKKSKKNVFRSQELEPIPDSLDDSETISERLDSTHHGGAVGAGEECESTKESHSIKKKSKKKKHKSVALATSSDSASVTDSKAKNALVDSSEGSGAVREEDVDHRPAEAEAQACSTEKHREAMQRLEPTHEEESNSESASNSAARHISEDRRESDDSDVDLGSAVRQLREFIPDIQERAATTIRRMYRDDLGRFKEFKAQGVAIRFGKFSAKENKQIEKNVQDFLSLTGIESADKLLYTDRYPEEKTLITNLKRKHAFRLHIGKGIARPWKLVYYRAKKIFDVNNYKGRYNEEDTKKLKAYHSLHGNDWKKIGAMVARSSLSVALKFSQIGGTRNQGAWSKAETQRLIKAVEDVILKKMSPQELRELDSKLQEDPEGRLSIVREKLYKGISWVEVEARVETRNWMQCKSKWTEILTKRMTHGGFVYRGVNALQAKITLIERLYELNVNDANEIDWEDLASAIGDVPPPFVQAKFYKLKAACVPFWQKKTFPEIIDYLYKNSLPLLKEKLDKKMKKKDGQIQTPAAPKQDFLFKDIFHCDDDSDEGSPEEPSASDVQ", "length": 859 }, "evidence": [ { "id": "MGI:105044", "url": "https://alliancegenome.org/gene/MGI:105044#orthology", "database": "AGR" }, { "id": "HGNC:12397", "url": "https://alliancegenome.org/gene/HGNC:12397#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041008-214", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041008-214#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "F1Q786", "url": "https://www.uniprot.org/uniprotkb/F1Q786" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "F1Q786", "url": "https://www.uniprot.org/uniprotkb/F1Q786" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "termination of RNA polymerase I transcription", "id": "GO:0006363", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006363", "evidence": [ { "database": "UniProtKB", "id": "F1Q786", "url": "https://www.uniprot.org/uniprotkb/F1Q786" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 295, "end_pos": 297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 546, "end_pos": 548, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1Q786", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q786" }, { "id": "PS51294", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51294" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "HTH myb-type", "eco_id": "ECO_0000259", "start_pos": 288, "end_pos": 340, "start_aa": "Asp", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1Q786", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q786" }, { "id": "PS50090", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50090" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb-like", "eco_id": "ECO_0000259", "start_pos": 288, "end_pos": 337, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 134, "end_pos": 136 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 295, "end_pos": 297 }, { "start_pos": 546, "end_pos": 548 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FB37-1", "uniprot_ac": "E7FB37", "uniprot_id": "E7FB37_DANRE", "mass": { "chemical_mass": 56928.0, "monoisotopic_mass": 56928.0 }, "refseq": { "ac": "XP_009303446", "name": "polypyrimidine tract-binding protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303446" }, "gene_names": [ { "name": "ptbp3", "type": "recommended", "evidence": [ { "id": "E7FB37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FB37" } ] }, { "name": "ptbp3", "type": "synonym", "evidence": [ { "id": "XP_009303446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303446" } ] } ], "protein_names": [ { "name": "Polypyrimidine tract-binding protein 1", "type": "recommended", "evidence": [ { "id": "E7FB37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FB37/entry#names_and_taxonomy" } ] }, { "name": "polypyrimidine tract-binding protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_009303446", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303446" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009303446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303446" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FB37", "url": "https://www.uniprot.org/uniprotkb/E7FB37" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ptbp3", "url": "https://www.uniprot.org/uniprotkb/E7FB37", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091116-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000043757", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000043757", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12784", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12784", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "798982", "url": "https://www.ncbi.nlm.nih.gov/gene/798982", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:798982", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798982", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VIFQKSG", "url": "https://omabrowser.org/oma/group/VIFQKSG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7FB37", "url": "https://www.orthodb.org/?gene=E7FB37", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15592", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15592", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11835", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11835", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22976", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22976", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009303446", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009303446", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TW76", "url": "https://www.uniprot.org/uniprotkb/A0AB32TW76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TW76-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TW76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FB37", "url": "https://www.uniprot.org/uniprotkb/E7FB37", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FB37-1", "url": "https://www.uniprot.org/uniprotkb/E7FB37-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091116-1", "url": "https://zfin.org/ZDB-GENE-091116-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSSTPSTTANGTDSKQYKGDRSPCAPSRVLHVRKVPIEVSEAEVVSLGVPFGKVTNLLMLKGKNQAFIEMASEEAAMTMVNYYTTATPHVRNQPVYIQYSNHRELKTDNLPNQGRAQAALQAVNAVHTGNMSLSGTATASDGGMMPGQSPVLRIIVENLYYPVSLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPMNAHHAKVALDGQNIYNGCCTLRVEFSKLTSLNVKYNNDKSRDFTRLDLPSGDGQPTLDPTMQTAFGAPGIISSPYPGAAGFAPAIGFPQAGLSMQAMPGALGPLTIPSSAMTGRMAIHGMTPTAIHSVLLVSNLNPDSISPHELFILFGVYGDVHRVKILFNKKENALIQMADATQAQLAMSHLNGQRLYGKVIRVTISKHQTVQLPREGQEDQGLTKDFSGSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSTTDDFLKDLFASSGYTVKAFKFFQKDRKMALIQLGSVEEAIQALIHLHNHDLGENHHLRVSFSKSTI", "length": 522, "header": "tr|E7FB37-1|E7FB37_DANRE Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Danio rerio OX=7955 GN=ptbp3 PE=1 SV=1 CANONICAL=E7FB37-1" }, "isoforms": [ { "isoform_ac": "A0AB32TW76-1", "url": "https://www.uniprot.org/uniprotkb/E7FB37/entry#A0AB32TW76-1", "sequence": { "sequence": "MANGTDSKQYKGDRSPCAPSRVLHVRKVPIEVSEAEVVSLGVPFGKVTNLLMLKGKNQAFIEMASEEAAMTMVNYYTTATPHVRNQPVYIQYSNHRELKTDNLPNQGRAQAALQAVNAVHTGNMSLSGTATASDGGMMPGQSPVLRIIVENLYYPVSLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPMNAHHAKVALDGQNIYNGCCTLRVEFSKLTSLNVKYNNDKSRDFTRLDLPSGDGQPTLDPTMQTAFGAPGIISSPYPGAAGFAPAIGFPQAGLSMQAMPGALGPLTIPSSAMTGRMAIHGMTPTAIHSVLLVSNLNPDSISPHELFILFGVYGDVHRVKILFNKKENALIQMADATQAQLAMSHLNGQRLYGKVIRVTISKHQTVQLPREGQEDQGLTKDFSGSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSTTDDFLKDLFASSGYTVKAFKFFQKDRKMALIQLGSVEEAIQALIHLHNHDLGENHHLRVSFSKSTI", "length": 514, "header": "tr|A0AB32TW76-1|E7FB37_DANRE Computationally mapped isoform of Polypyrimidine tract-binding protein 1 OS=Danio rerio OX=7955 GN=ptbp3 PE=1 SV=1 CANONICAL=E7FB37-1" }, "locus": {} }, { "isoform_ac": "E7FB37-1", "url": "https://www.uniprot.org/uniprotkb/E7FB37/entry#E7FB37-1", "sequence": { "sequence": "MSSSTPSTTANGTDSKQYKGDRSPCAPSRVLHVRKVPIEVSEAEVVSLGVPFGKVTNLLMLKGKNQAFIEMASEEAAMTMVNYYTTATPHVRNQPVYIQYSNHRELKTDNLPNQGRAQAALQAVNAVHTGNMSLSGTATASDGGMMPGQSPVLRIIVENLYYPVSLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPMNAHHAKVALDGQNIYNGCCTLRVEFSKLTSLNVKYNNDKSRDFTRLDLPSGDGQPTLDPTMQTAFGAPGIISSPYPGAAGFAPAIGFPQAGLSMQAMPGALGPLTIPSSAMTGRMAIHGMTPTAIHSVLLVSNLNPDSISPHELFILFGVYGDVHRVKILFNKKENALIQMADATQAQLAMSHLNGQRLYGKVIRVTISKHQTVQLPREGQEDQGLTKDFSGSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSTTDDFLKDLFASSGYTVKAFKFFQKDRKMALIQLGSVEEAIQALIHLHNHDLGENHHLRVSFSKSTI", "length": 522, "header": "tr|E7FB37-1|E7FB37_DANRE Isoform 1 of Polypyrimidine tract-binding protein 1 OS=Danio rerio OX=7955 GN=ptbp3 PE=1 SV=1 CANONICAL=E7FB37-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:798982", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798982", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4K6W9-1", "protein_name": "Hephaestus, isoform Y", "gene_name": "heph", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMSCPIPMPMPISSLHKSEFEPVNIGVKQMQLLHAPASTHPHPHPHQHPQHSAASAAAYQAMQVHQQQHQQQQQAAVFHHQVAAIAAQQQQQQQQAQVQHQQQMQQQFHYQAQAQAQAQAMLQTYMQLQVNSAVGVSTAPATPTKPVAAQIPGAISGPIAGPVPVSVPTQFFTAPSTPLTIIPAAAVASSAMFATAATPTSAATTPTNNVNNTVNLSAVSRTTTTTTKKQPQAVADAVLSAVGGNVGTAVGGGTISSLLGPEPLPIMPHHLPLASVRGCSSASSGCSSASSDCSMPSPTSLHLSSPKKVRIDEQYIYKLNYLRGSDELLSQAAVMAPASDNNNQDLATKKAKLEPGTVLAGGIAKASKVIHLRNIPNESGEADVIALGIPFGRVTNVLVLKGKNQAFIEMADEISATSMVSCYTVTPPQMRGRMVYVQFSNHRELKTDQGHNNSTAHSDYSVQSPASGSPLPLSAAANATSNNANSSSDSNSAMGILQNTSAVNAGGNTNAAGGPNTVLRVIVESLMYPVSLDILHQIFQRYGKVLKIVTFTKNNSFQALIQYPDANSAQHAKSLLDGQNIYNGCCTLRIDNSKLTALNVKYNNDKSRDFTNPALPPGEPGVDIMPTAGGLMNTNDLLLIAARQRPSLSVNGLGAPGVLPPFALGLGTPLTGGYNNALPNLAAFSLANSGALQTTAPAMRGYSNVLLVSNLNEEMVTPDALFTLFGVYGDVQRVKILYNKKDSALIQMAEPQQAYLAMSHLDKLRLWGKPIRVMASKHQAVQLPKEGQPDAGLTRDYSQNPLHRFKKPGSKNYQNIYPPSATLHLSNIPSSCSEDDIKEAFTSNSFEVKAFKFFPKDRKMALLQLLSVEEAVLALIKMHNHQLSESNHLRVSFSKSNI", "length": 898 }, "evidence": [ { "id": "HGNC:10253", "url": "https://alliancegenome.org/gene/HGNC:10253#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091116-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-1#orthology", "database": "AGR" }, { "id": "MGI:1923334", "url": "https://alliancegenome.org/gene/MGI:1923334#orthology", "database": "AGR" }, { "id": "RGD:621671", "url": "https://alliancegenome.org/gene/RGD:621671#orthology", "database": "AGR" }, { "id": "FB:FBgn0011224", "url": "https://alliancegenome.org/gene/FB:FBgn0011224#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8I5ZR32-1", "protein_name": "Polypyrimidine tract binding protein 1, pseudogene 3", "gene_name": "Ptbp1-ps3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "YANGNDSKKFKGDNRSTGVPSRVIHVQKLPSNVTEGKVISLELPFGNVTNLLMLKGKNQASIEMSTEEAANTMVNYYTWVAPVLHGQPIYIQFSNHKEFKTHSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAKAGQRPVIRFIVENLFYPVTLDALHQIFSKFGAFQVLLQHADPVSAQHAKLSLDGQNIYNACCTLHINFSKLTSLDVKYNNDKSRDYTRPALPSGDIFFVPGITSDSPNAGAGFPLTFATPQAAGLSVPNVHGALATLAIPSAAVAAAGRIAIPGLAGVGNSILLVSNLNPERVTAQSLFILFSIYGDVKRMKILFNKKENALLQMADGNQAQLAMSHLNGHKLDGKSVRITPSKHQSVQLPHERQEDQGLTKNYDSSPLHCVQKPGSKNFQNIFPPSATLHLSNIPPSVSEDGLKSLFSSNGDMAKGFKFFKKDHKMALIQMGSVEEAVQALIELHSHDLGENYHPRVFFSKSTI", "length": 495 }, "evidence": [ { "id": "FB:FBgn0011224", "url": "https://alliancegenome.org/gene/FB:FBgn0011224#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0XPG4-1", "protein_name": "Polypyrimidine tract binding protein 3", "gene_name": "PTBP3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQEEMTSEDETKQTTEEGEEDLVTDVSDDGFKMCLSIYVVLGRVLGQNIAVCLFSSDSLSQHGPDNLLSSSVSGKPLTVSNSTPAKGGGNDNKKLKGGRLPCLPSRVLHLRQIPDNATEADVISLGLPFGKVTNVLILRGKSQAFLEMASEENAVSMVNYCSTAIPHIHNQPVYVQYSNHRELKTDSLPSQASAQAALQVVNTVQCGNVGVTSTFAAESGLPPGHSSVLRIIIENLFYPVSLEVLYQIFSKFGFVLKIVTFTRNNQFQALIQYAEPVNAYYAKMALNGRNIYNACCTLHIDFSKLTSLKVKYNNEKSRDFTRFDLPAADGQLPLDPAIIAAFGSQGIIFQPYVGTGGIGPVTYFPQGAVTTSVASVRMSNPGVPGNSVLLVSNLNPEAITPHGLFILFGAYGDVLRVKIMFKNKENALVQMADATQAQIAISNLNGQKLYGKFIRATLSKHQNIQLPREGEEDNGLTKDYSNSPLHRFKNPGSKNFQNIFPPSATLHLSNIPPSVSFDDLKSLFARTGSTVKAFRFFQRDCKMALIQLGSVEEAVHALIELHNYDLGENHHLRVSFSKSTI", "length": 581 }, "evidence": [ { "id": "E7FB37", "url": "https://omabrowser.org/oma/group/E7FB37/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0AAA9T1Y3-1", "protein_name": "Polypyrimidine tract-binding protein 3", "gene_name": "PTBP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAAAEDELLLPRLPELFETSKQLLDEVEIAAEPTSSQIIQDKVFKGLDLLKKAAEMLSQLDLFSQNEDLEEIASTDLKYLMVPAFQGAFTMKQVSPSKRLDHLQWAREHFLNFLTQCQYYHVAKFELPKTKTNLAGNNTANSSMAYPSIIAMASQRQAKKERYKQKKEVEHRLSALKSAVESGQADDEHVREYYLLHLRRWIGISLEEIESIDQEIKILREKDSTHEASTSQSSHQDRPPMKPFVLTQNMAQAKVFGAGYPSLASMTVNDWYEQHRKFGALPDQGIATTMSEFKRAAQQQEDQEHEEEEDDEQAVCRAREWDDWKDTHPRGYGNRQNMANGNDNKKFKGDRPLCSPSRVLHLRKIPSDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPVTPHLRSQPVFIQYSNHRELKTDNLPNQARAQAALQAVSTVQSGSLALPGAPTNEGTILPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPLNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAGLGPGALGPLAITSSAVTGRMAIPGAGGMPGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "length": 853 }, "evidence": [ { "id": "E7FB37", "url": "https://omabrowser.org/oma/group/E7FB37/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O95758-3", "protein_name": "Polypyrimidine tract-binding protein 3", "gene_name": "PTBP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGVVTDLITVGLKRGSDELLSSGIINGPFTMNSSTPSTANGNDSKKFKRDRPPCSPSRVLHLRKIPCDVTEAEIISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMVNYYTPITPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGSLALSGGPSNEGTVLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAHYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIISSPYAGAAGFAPAIGFPQATGLSVPAVPGALGPLTITSSAVTGRMAIPGASGIPGNSVLLVTNLNPDLITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADANQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTVDDLKNLFIEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "length": 552 }, "evidence": [ { "id": "HGNC:10253", "url": "https://alliancegenome.org/gene/HGNC:10253#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091116-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-1#orthology", "database": "AGR" }, { "id": "MGI:1923334", "url": "https://alliancegenome.org/gene/MGI:1923334#orthology", "database": "AGR" }, { "id": "RGD:621671", "url": "https://alliancegenome.org/gene/RGD:621671#orthology", "database": "AGR" }, { "id": "FB:FBgn0011224", "url": "https://alliancegenome.org/gene/FB:FBgn0011224#orthology", "database": "AGR" }, { "id": "E7FB37", "url": "https://omabrowser.org/oma/group/E7FB37/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P17225-1", "protein_name": "Polypyrimidine tract-binding protein 1", "gene_name": "Ptbp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSTCVSNGPFIMSSSASAANGNDSKKFKGDNRSAGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIMSASPYAGAGFPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAASRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI", "length": 555 }, "evidence": [ { "id": "FB:FBgn0011224", "url": "https://alliancegenome.org/gene/FB:FBgn0011224#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P26599-3", "protein_name": "Polypyrimidine tract-binding protein 1", "gene_name": "PTBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSTCVTNGPFIMSSNSASAANGNDSKKFKGDSRSAGVPSRVIHIRKLPIDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMNTEEAANTMVNYYTSVTPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIISASPYAGAGFPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGNQAQLAMSHLNGHKLHGKPIRITLSKHQNVQLPREGQEDQGLTKDYGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEEDLKVLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIDLHNHDLGENHHLRVSFSKSTI", "length": 557 }, "evidence": [ { "id": "FB:FBgn0011224", "url": "https://alliancegenome.org/gene/FB:FBgn0011224#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q00438-1", "protein_name": "Polypyrimidine tract-binding protein 1", "gene_name": "Ptbp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGIVPDIAVGTKRGSDELFSTCVSNGPFIMSSSASAANGNDSKKFKGDNRSTGVPSRVIHVRKLPSDVTEGEVISLGLPFGKVTNLLMLKGKNQAFIEMSTEEAANTMVNYYTSVAPVLRGQPIYIQFSNHKELKTDSSPNQARAQAALQAVNSVQSGNLALAASAAAVDAGMAMAGQSPVLRIIVENLFYPVTLDVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVSAQHAKLSLDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDYTRPDLPSGDSQPSLDQTMAAAFGAPGIMSASPYAGAGFPPTFAIPQAAGLSVPNVHGALAPLAIPSAAAAAAAAGRIAIPGLAGAGNSVLLVSNLNPERVTPQSLFILFGVYGDVQRVKILFNKKENALVQMADGSQAQLAMSHLNGHKLHGKSVRITLSKHQSVQLPREGQEDQGLTKDYGSSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVSEDDLKSLFSSNGGVVKGFKFFQKDRKMALIQMGSVEEAVQALIELHNHDLGENHHLRVSFSKSTI", "length": 556 }, "evidence": [ { "id": "FB:FBgn0011224", "url": "https://alliancegenome.org/gene/FB:FBgn0011224#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q66H20-1", "protein_name": "Polypyrimidine tract-binding protein 2", "gene_name": "Ptbp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDGIVTEVAVGVKRGSDELLSGSVLSSPNSNMSGMVVTANGNDSKKFKGEDKMDGAPSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQRAQVVLQAVTAVQTANTPLSGTTVSESAVTPAQSPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPALDPAIAAAFAKETSLLAVPGALSPLAIPNAAAAAAAAAAGRVGMPGVSAGGNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQDHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI", "length": 531 }, "evidence": [ { "id": "FB:FBgn0011224", "url": "https://alliancegenome.org/gene/FB:FBgn0011224#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80XZ1-1", "protein_name": "Polypyrimidine tract-binding protein", "gene_name": "Smptb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRNSPPAAEGNGSKRFKGDSWGTRDPSRLVHILRLPSCVTEGEILCLALPFGEVSNLLFLRAKNQAFVEMSTEESANTMINYYTWMPPVLRGQPVHIQFAHYRELKVSSSPSQEISLSQAGDSREATASSLVAVPGQAAASGQTAVPSQLGAQPCLPPEDSYQAGTVALAPPASAVDTELVVAWQSPVLRILVENYFYRVTLEVLHQIFSRFGTVLKIITCTKNNRFQALLQYAHVMSAERAKLFLDGQNIYDACCTLRISFSGLTNLMVKYNNDKSRDYMRPDLPSDDSQPSPVQVQNMASALPAPAMSSASPYASIALPHTFAIPQAAGLANPEVFKTLHPQAIQEVAMASSSSSSSTAAAAVGAAEIAAAAVPGAEGSMVTSGSPGVGSPVLLVANLNQEKVTPRSLFILFGAYGDVHRVKILFNRKENALVQMADGSQAELALRHLNGHKLYGKALCILLSKHQSVKLPREGKEDQGLTKDYANSPLHRFKKPGSKNFQNIFPPSATLHLSNLPSLVSEEELKNLFSSNGYAVKAFRFFPKNHKMALIRMGSTEEAIQALVDLHGHLLGQNHHMRVSFSRMTI", "length": 588 }, "evidence": [ { "id": "FB:FBgn0011224", "url": "https://alliancegenome.org/gene/FB:FBgn0011224#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8BHD7-1", "protein_name": "Polypyrimidine tract-binding protein 3", "gene_name": "Ptbp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNSSTSAGVYANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATANEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVPAVPGALGPLTLTSSAVSGRMAIPGASGMPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQLAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "length": 523 }, "evidence": [ { "id": "HGNC:10253", "url": "https://alliancegenome.org/gene/HGNC:10253#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091116-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-1#orthology", "database": "AGR" }, { "id": "MGI:1923334", "url": "https://alliancegenome.org/gene/MGI:1923334#orthology", "database": "AGR" }, { "id": "RGD:621671", "url": "https://alliancegenome.org/gene/RGD:621671#orthology", "database": "AGR" }, { "id": "FB:FBgn0011224", "url": "https://alliancegenome.org/gene/FB:FBgn0011224#orthology", "database": "AGR" }, { "id": "E7FB37", "url": "https://omabrowser.org/oma/group/E7FB37/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q91Z31-1", "protein_name": "Polypyrimidine tract-binding protein 2", "gene_name": "Ptbp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDGIVTEVAVGVKRGSDELLSGSVLSSPNSNMSGMVVTANGNDSKKFKGEDKMDGAPSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQRAQVVLQAVTAVQTANTPLSGTTVSESAVTPAQSPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPALDPAIAAAFAKETSLLAVPGALSPLAIPNAAAAAAAAAAGRVGMPGVSAGGNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQDHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI", "length": 531 }, "evidence": [ { "id": "FB:FBgn0011224", "url": "https://alliancegenome.org/gene/FB:FBgn0011224#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UKA9-1", "protein_name": "Polypyrimidine tract-binding protein 2", "gene_name": "PTBP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDGIVTEVAVGVKRGSDELLSGSVLSSPNSNMSSMVVTANGNDSKKFKGEDKMDGAPSRVLHIRKLPGEVTETEVIALGLPFGKVTNILMLKGKNQAFLELATEEAAITMVNYYSAVTPHLRNQPIYIQYSNHKELKTDNTLNQRAQAVLQAVTAVQTANTPLSGTTVSESAVTPAQSPVLRIIIDNMYYPVTLDVLHQIFSKFGAVLKIITFTKNNQFQALLQYGDPVNAQQAKLALDGQNIYNACCTLRIDFSKLVNLNVKYNNDKSRDYTRPDLPSGDGQPALDPAIAAAFAKETSLLAVPGALSPLAIPNAAAAAAAAAAGRVGMPGVSAGGNTVLLVSNLNEEMVTPQSLFTLFGVYGDVQRVKILYNKKDSALIQMADGNQSQLAMNHLNGQKMYGKIIRVTLSKHQTVQLPREGLDDQGLTKDFGNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVAEEDLRTLFANTGGTVKAFKFFQDHKMALLQMATVEEAIQALIDLHNYNLGENHHLRVSFSKSTI", "length": 531 }, "evidence": [ { "id": "FB:FBgn0011224", "url": "https://alliancegenome.org/gene/FB:FBgn0011224#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z118-1", "protein_name": "Polypyrimidine tract-binding protein 3", "gene_name": "Ptbp3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNNSTSAGVYANGNDNKKFKGDRPPCSPSRVLHLRKIPCDVTEAEVISLGLPFGKVTNLLMLKGKSQAFLEMASEEAAVTMINYYTPVTPHLRSQPVYIQYSNHRELKTDNLPNQARAQAALQAVSAVQSGNLSLPGATSNEGTLLPGQSPVLRIIIENLFYPVTLEVLHQIFSKFGTVLKIITFTKNNQFQALLQYADPVNAQYAKMALDGQNIYNACCTLRIDFSKLTSLNVKYNNDKSRDFTRLDLPTGDGQPSLEPPMAAAFGAPGIMSSPYAGAAGFAPAIAFPQAAGLSVSAVPGALGPLTLTSSAVSGRMAIPGASGIPGNSVLLVTNLNPDFITPHGLFILFGVYGDVHRVKIMFNKKENALVQMADASQAQIAMNHLSGQRLYGKVLRATLSKHQAVQLPREGQEDQGLTKDFSNSPLHRFKKPGSKNFQNIFPPSATLHLSNIPPSVTMDDLKNLFTEAGCSVKAFKFFQKDRKMALIQLGSVEEAIQALIELHNHDLGENHHLRVSFSKSTI", "length": 523 }, "evidence": [ { "id": "HGNC:10253", "url": "https://alliancegenome.org/gene/HGNC:10253#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091116-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091116-1#orthology", "database": "AGR" }, { "id": "MGI:1923334", "url": "https://alliancegenome.org/gene/MGI:1923334#orthology", "database": "AGR" }, { "id": "RGD:621671", "url": "https://alliancegenome.org/gene/RGD:621671#orthology", "database": "AGR" }, { "id": "FB:FBgn0011224", "url": "https://alliancegenome.org/gene/FB:FBgn0011224#orthology", "database": "AGR" }, { "id": "E7FB37", "url": "https://omabrowser.org/oma/group/E7FB37/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E7FB37", "url": "https://www.uniprot.org/uniprotkb/E7FB37" } ], "pmid": "" }, { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E7FB37", "url": "https://www.uniprot.org/uniprotkb/E7FB37" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7FB37", "url": "https://www.uniprot.org/uniprotkb/E7FB37" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "mRNA processing", "id": "GO:0006397", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006397", "evidence": [ { "database": "UniProtKB", "id": "E7FB37", "url": "https://www.uniprot.org/uniprotkb/E7FB37" } ], "pmid": "" }, { "name": "negative regulation of gene expression", "id": "GO:0010629", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010629", "evidence": [ { "database": "UniProtKB", "id": "E7FB37", "url": "https://www.uniprot.org/uniprotkb/E7FB37" } ], "pmid": "" }, { "name": "RNA splicing", "id": "GO:0008380", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008380", "evidence": [ { "database": "UniProtKB", "id": "E7FB37", "url": "https://www.uniprot.org/uniprotkb/E7FB37" } ], "pmid": "" }, { "name": "negative regulation of mRNA metabolic process", "id": "GO:1903312", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1903312", "evidence": [ { "database": "UniProtKB", "id": "E7FB37", "url": "https://www.uniprot.org/uniprotkb/E7FB37" } ], "pmid": "" }, { "name": "regulation of RNA splicing", "id": "GO:0043484", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043484", "evidence": [ { "database": "UniProtKB", "id": "E7FB37", "url": "https://www.uniprot.org/uniprotkb/E7FB37" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FB37", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FB37" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 103, "start_aa": "Arg", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 131, "end_pos": 133 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F042-1", "uniprot_ac": "E7F042", "uniprot_id": "E7F042_DANRE", "mass": { "chemical_mass": 53026.0, "monoisotopic_mass": 53026.0 }, "refseq": { "ac": "XP_005169243", "name": "vascular endothelial zinc finger 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169243" }, "gene_names": [ { "name": "vezf1a", "type": "recommended", "evidence": [ { "id": "E7F042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F042" } ] }, { "name": "vezf1a", "type": "synonym", "evidence": [ { "id": "XP_005169243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169243" } ] } ], "protein_names": [ { "name": "Myc-associated zinc finger protein", "type": "recommended", "evidence": [ { "id": "E7F042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F042/entry#names_and_taxonomy" } ] }, { "name": "Pur-1", "type": "synonym", "evidence": [ { "id": "E7F042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F042/entry#names_and_taxonomy" } ] }, { "name": "Purine-binding transcription factor", "type": "synonym", "evidence": [ { "id": "E7F042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F042/entry#names_and_taxonomy" } ] }, { "name": "vascular endothelial zinc finger 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005169243", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169243" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005169243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169243" } ] } ], "disease": [ { "disease_id": "DOID:12930", "recommended_name": { "id": "DOID:12930", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently." }, "synonyms": [ { "id": "DOID:12930", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12930", "name": "primary dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "Familial dilated cardiomyopathy with conduction defect due to LMNA mutation is a rare familial dilated cardiomyopathy characterized by left ventricular enlargement and/or reduced systolic function preceded or accompanied by significant conduction system disease and/or arrhythmias including bradyarrhythmias, supraventricular or ventricular arrhythmias. Disease onset is usually in early to mid-adulthood. Sudden cardiac death may occur and may be the presenting symptom. In some cases, it is associated with skeletal myopathy and elevated serum creatine kinase." }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "CDCD1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "LMNA familial isolated dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy dilated with conduction defect type 1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "familial dilated cardiomyopathy with conduction defect due to LMNA mutation", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "familial isolated dilated cardiomyopathy caused by mutation in LMNA", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, 1A", "description": "" }, { "id": "MIM:115200", "resource": "MIM", "url": "https://www.omim.org/entry/115200", "name": "Cardiomyopathy, dilated, 1A", "description": "Cardiomyopathy, dilated, 1A" } ], "unlinked_id_list": [], "evidence": [ { "id": "12930", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12930" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F042", "url": "https://www.uniprot.org/uniprotkb/E7F042" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "vezf1a", "url": "https://www.uniprot.org/uniprotkb/E7F042", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040108-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000008247", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000008247", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "567023", "url": "https://www.ncbi.nlm.nih.gov/gene/567023", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050331", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050331", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567023", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567023", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NKGNEVC", "url": "https://omabrowser.org/oma/group/NKGNEVC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BGF2", "url": "https://www.orthodb.org/?gene=A0A8M2BGF2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UV60", "url": "https://www.orthodb.org/?gene=A0A8N7UV60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F042", "url": "https://www.orthodb.org/?gene=E7F042", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16515:SF49", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16515:SF49", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24393:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24393:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24408:SF30", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24408:SF30", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005169243", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169243", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BGF2", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BGF2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BGF2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BGF2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UV60", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UV60-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UV60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TWG2", "url": "https://www.uniprot.org/uniprotkb/A0AB32TWG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TWG2-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TWG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TZT0", "url": "https://www.uniprot.org/uniprotkb/A0AB32TZT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TZT0-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TZT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GN79", "url": "https://www.uniprot.org/uniprotkb/A0AC58GN79", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GN79-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GN79-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F042", "url": "https://www.uniprot.org/uniprotkb/E7F042", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F042-1", "url": "https://www.uniprot.org/uniprotkb/E7F042-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040108-4", "url": "https://zfin.org/ZDB-GENE-040108-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMEQSWSSFLFQQANEALHHQHQVAPNSLLPLLNSEPQDQKPVMPIPLDHKPPVSAADLLKDNVVSGTGGGGGGGNAGPMVVVKKEHKSKTPFICGYCNKAFRDSYHLRRHESCHTGIKMVSRPKKTAQAAPTMVPLISSMSRESTGDPSYISTVAGILSTATTSTSSASTVMSPTSMSNVTQHSAPKKPPKPVKKNHGCEMCGKAFRDVYHLNRHKLSHSDEKPFECPICQQRFKRKDRMTYHVRSHDGGVHKPYVCSVCGKGFSRPDHLSCHVKHVHSSERPFKCQVTACTSAFATKDRLRSHMIRHEGKVTCNVCGKMLSAAYITSHLKTHGQSNFNNACNKGYALSVHGARHSGDWQWNHSGLRKDNTEVCNSASSTPVTPAAPITSTMNRGNTSNPVTIAAQMNISTNTVNITSPVSLQHQVTITGPVNIASVNIPASAPMNIAHPVAITTPMPMNIATPLNIAMRPMDSMPFLSQVLPSSPW", "length": 488, "header": "tr|E7F042-1|E7F042_DANRE Isoform 1 of Myc-associated zinc finger protein OS=Danio rerio OX=7955 GN=vezf1a PE=1 SV=1 CANONICAL=E7F042-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BGF2-1", "url": "https://www.uniprot.org/uniprotkb/E7F042/entry#A0A8M2BGF2-1", "sequence": { "sequence": "MMEQSWSSFLFQQANEALHHQHQVAPNSLLPLLNSEPQDQKPVMPIPLDHKPPVSAADLLKDNVVSGTGGGGGGGNAGPMVVVKKEHKSKTPFICGYCNKAFRDSYHLRRHESCHTGIKMVSRPKKTAQAAPTMVPLISSMSRESTGDPSYISTVAGILSTATTSTSSASTVMSPTSMSNVTQHSAPKKPPKPVKKNHGCEMCGKAFRDVYHLNRHKLSHSDEKPFECPICQQRFKRKDRMTYHVRSHDGGVHKPYVCSVCGKGFSRPDHLSCHVKHVHSSERPFKCQVTACTSAFATKDRLRSHMIRHEGKVTCNVCGKMLSAAYITSHLKTHGQSNFNNACNKGDWQWNHSGLRKDNTEVCNSASSTPVTPAAPITSTMNRGNTSNPVTIAAQMNISTNTVNITSPVSLQHQVTITGPVNIASVNIPASAPMNIAHPVAITTPMPMNIATPLNIAMRPMDSMPFLSQVLPSSPW", "length": 476, "header": "tr|A0A8M2BGF2-1|E7F042_DANRE Computationally mapped isoform of Myc-associated zinc finger protein OS=Danio rerio OX=7955 GN=vezf1a PE=1 SV=1 CANONICAL=E7F042-1" }, "locus": {} }, { "isoform_ac": "A0A8N7UV60-1", "url": "https://www.uniprot.org/uniprotkb/E7F042/entry#A0A8N7UV60-1", "sequence": { "sequence": "MMEQSWSSFLFQQANEALHHQHQVAPNSLLPLLNSEPQDQKPVMPIPLDHKPPVSAADLLKDNVVSGTGGGGGGGNAGPMVVVKKEHKSKTPFICGYCNKAFRDSYHLRRHESCHTGIKMVSRPKKTAQAAPTMVPLISSMSRESTGDPSYISTVAGILSTATTSTSSASTVMSPTSMSNVTQHSAPKKPPKPVKKNHGCEMCGKAFRDVYHLNRHKLSHSDEKPFECPICQQRFKRKDRMTYHVRSHDGGVHKPYVCSVCGKGFSRPDHLSCHVKHVHSSERPFKCQVTACTSAFATKDRLRSHMIRHEGKVTCNVCGKMLSAAYITSHLKTHGQSNFNNACNKDNTEVCNSASSTPVTPAAPITSTMNRGNTSNPVTIAAQMNISTNTVNITSPVSLQHQVTITGPVNIASVNIPASAPMNIAHPVAITTPMPMNIATPLNIAMRPMDSMPFLSQVLPSSPW", "length": 464, "header": "tr|A0A8N7UV60-1|E7F042_DANRE Computationally mapped isoform of Myc-associated zinc finger protein OS=Danio rerio OX=7955 GN=vezf1a PE=1 SV=1 CANONICAL=E7F042-1" }, "locus": {} }, { "isoform_ac": "A0AB32TWG2-1", "url": "https://www.uniprot.org/uniprotkb/E7F042/entry#A0AB32TWG2-1", "sequence": { "sequence": "MMEQSWSSFLFQANEALHHQHQVAPNSLLPLLNSEPQDQKPVMPIPLDHKPPVSAADLLKDNVVSGTGGGGGGGNAGPMVVVKKEHKSKTPFICGYCNKAFRDSYHLRRHESCHTGIKMVSRPKKTAQAAPTMVPLISSMSRESTGDPSYISTVAGILSTATTSTSSASTVMSPTSMSNVTQHSAPKKPPKPVKKNHGCEMCGKAFRDVYHLNRHKLSHSDEKPFECPICQQRFKRKDRMTYHVRSHDGGVHKPYVCSVCGKGFSRPDHLSCHVKHVHSSERPFKCQVTACTSAFATKDRLRSHMIRHEGKVTCNVCGKMLSAAYITSHLKTHGQSNFNNACNKGYALSVHGARHSGDWQWNHSGLRKDNTEVCNSASSTPVTPAAPITSTMNRGNTSNPVTIAAQMNISTNTVNITSPVSLQHQVTITGPVNIASVNIPASAPMNIAHPVAITTPMPMNIATPLNIAMRPMDSMPFLSQVLPSSPW", "length": 487, "header": "tr|A0AB32TWG2-1|E7F042_DANRE Computationally mapped isoform of Myc-associated zinc finger protein OS=Danio rerio OX=7955 GN=vezf1a PE=1 SV=1 CANONICAL=E7F042-1" }, "locus": {} }, { "isoform_ac": "A0AB32TZT0-1", "url": "https://www.uniprot.org/uniprotkb/E7F042/entry#A0AB32TZT0-1", "sequence": { "sequence": "MMEQSWSSFLFQANEALHHQHQVAPNSLLPLLNSEPQDQKPVMPIPLDHKPPVSAADLLKDNVVSGTGGGGGGGNAGPMVVVKKEHKSKTPFICGYCNKAFRDSYHLRRHESCHTGIKMVSRPKKTAQAAPTMVPLISSMSRESTGDPSYISTVAGILSTATTSTSSASTVMSPTSMSNVTQHSAPKKPPKPVKKNHGCEMCGKAFRDVYHLNRHKLSHSDEKPFECPICQQRFKRKDRMTYHVRSHDGGVHKPYVCSVCGKGFSRPDHLSCHVKHVHSSERPFKCQVTACTSAFATKDRLRSHMIRHEGKVTCNVCGKMLSAAYITSHLKTHGQSNFNNACNKDNTEVCNSASSTPVTPAAPITSTMNRGNTSNPVTIAAQMNISTNTVNITSPVSLQHQVTITGPVNIASVNIPASAPMNIAHPVAITTPMPMNIATPLNIAMRPMDSMPFLSQVLPSSPW", "length": 463, "header": "tr|A0AB32TZT0-1|E7F042_DANRE Computationally mapped isoform of Myc-associated zinc finger protein OS=Danio rerio OX=7955 GN=vezf1a PE=1 SV=1 CANONICAL=E7F042-1" }, "locus": {} }, { "isoform_ac": "A0AC58GN79-1", "url": "https://www.uniprot.org/uniprotkb/E7F042/entry#A0AC58GN79-1", "sequence": { "sequence": "MMEQSWSSFLFQANEALHHQHQVAPNSLLPLLNSEPQDQKPVMPIPLDHKPPVSAADLLKDNVVSGTGGGGGGGNAGPMVVVKKEHKSKTPFICGYCNKAFRDSYHLRRHESCHTGIKMVSRPKKTAQAAPTMVPLISSMSRESTGDPSYISTVAGILSTATTSTSSASTVMSPTSMSNVTQHSAPKKPPKPVKKNHGCEMCGKAFRDVYHLNRHKLSHSDEKPFECPICQQRFKRKDRMTYHVRSHDGGVHKPYVCSVCGKGFSRPDHLSCHVKHVHSSERPFKCQVTACTSAFATKDRLRSHMIRHEGKVTCNVCGKMLSAAYITSHLKTHGQSNFNNACNKGDWQWNHSGLRKDNTEVCNSASSTPVTPAAPITSTMNRGNTSNPVTIAAQMNISTNTVNITSPVSLQHQVTITGPVNIASVNIPASAPMNIAHPVAITTPMPMNIATPLNIAMRPMDSMPFLSQVLPSSPW", "length": 475, "header": "tr|A0AC58GN79-1|A0AC58GN79_DANRE Computationally mapped isoform of Myc-associated zinc finger protein OS=Danio rerio OX=7955 GN=vezf1a PE=1 SV=1 CANONICAL=E7F042-1" }, "locus": {} }, { "isoform_ac": "E7F042-1", "url": "https://www.uniprot.org/uniprotkb/E7F042/entry#E7F042-1", "sequence": { "sequence": "MMEQSWSSFLFQQANEALHHQHQVAPNSLLPLLNSEPQDQKPVMPIPLDHKPPVSAADLLKDNVVSGTGGGGGGGNAGPMVVVKKEHKSKTPFICGYCNKAFRDSYHLRRHESCHTGIKMVSRPKKTAQAAPTMVPLISSMSRESTGDPSYISTVAGILSTATTSTSSASTVMSPTSMSNVTQHSAPKKPPKPVKKNHGCEMCGKAFRDVYHLNRHKLSHSDEKPFECPICQQRFKRKDRMTYHVRSHDGGVHKPYVCSVCGKGFSRPDHLSCHVKHVHSSERPFKCQVTACTSAFATKDRLRSHMIRHEGKVTCNVCGKMLSAAYITSHLKTHGQSNFNNACNKGYALSVHGARHSGDWQWNHSGLRKDNTEVCNSASSTPVTPAAPITSTMNRGNTSNPVTIAAQMNISTNTVNITSPVSLQHQVTITGPVNIASVNIPASAPMNIAHPVAITTPMPMNIATPLNIAMRPMDSMPFLSQVLPSSPW", "length": 488, "header": "tr|E7F042-1|E7F042_DANRE Isoform 1 of Myc-associated zinc finger protein OS=Danio rerio OX=7955 GN=vezf1a PE=1 SV=1 CANONICAL=E7F042-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 384, "start_aa": "Thr", "end_pos": 384, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr384", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:567023", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567023", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZLS0-1", "protein_name": "Vascular endothelial zinc finger 1", "gene_name": "Vezf1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEANWTAFLFQAHEASHHQQQAAQNSLLPLLSSAVEPPDQKPLLPIPITQKPQAAPETLKDAIGIKKEKPKTSFVCTYCSKAFRDSYHLRRHQSCHTGIKLVSRAKKTPTTVVPLISTIAGDSSRTSLVSTIAGILSTVTTSSSGTNPSSSASTTAMPVPQSVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCSVCGKGFSRPDHLSCHVKHVHSTERPFKCQTCTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQQQQHVTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFNITSSVSSGTMSNPVTVAAAMSMRSPVNVSSAVNITSPMNIGHPVTITSPLSMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAAPLNIAMRPVESMPFLPQALPTSPPW", "length": 520 }, "evidence": [ { "id": "MGI:1313291", "url": "https://alliancegenome.org/gene/MGI:1313291#orthology", "database": "AGR" }, { "id": "HGNC:12949", "url": "https://alliancegenome.org/gene/HGNC:12949#orthology", "database": "AGR" }, { "id": "E7F042", "url": "https://omabrowser.org/oma/group/E7F042/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14119-1", "protein_name": "Vascular endothelial zinc finger 1", "gene_name": "VEZF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEANWTAFLFQAHEASHHQQQAAQNSLLPLLSSAVEPPDQKPLLPIPITQKPQGAPETLKDAIGIKKEKPKTSFVCTYCSKAFRDSYHLRRHESCHTGIKLVSRPKKTPTTVVPLISTIAGDSSRTSLVSTIAGILSTVTTSSSGTNPSSSASTTAMPVTQSVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCSVCGKGFSRPDHLSCHVKHVHSTERPFKCQTCTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQQQQQHVTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFSITSSVSSGTMSNPVTVAAAMSMRSPVNVSSAVNITSPMNIGHPVTITSPLSMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAAPLNIAMRPVESMPFLPQALPTSPPW", "length": 521 }, "evidence": [ { "id": "MGI:1313291", "url": "https://alliancegenome.org/gene/MGI:1313291#orthology", "database": "AGR" }, { "id": "HGNC:12949", "url": "https://alliancegenome.org/gene/HGNC:12949#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040108-4#orthology", "database": "AGR" }, { "id": "E7F042", "url": "https://omabrowser.org/oma/group/E7F042/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5SXC4-1", "protein_name": "Vascular endothelial zinc finger 1", "gene_name": "Vezf1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEANWTAFLFQAHEASHHQQQAAQNSLLPLLSSAVEPPDQKPLLPIPITQKPQAAPETLKDAIGIKKEKPKTSFVCTYCSKAFRDSYHLRRHQSCHTGIKLVSRAKKTPTTVVPLISTIAGDSSRTSLVSTIAGILSTVTTSSSGTNPSSSASTTSMPVPQSVKKPSKPVKKNHACEMCGKAFRDVYHLNRHKLSHSDEKPFECPICNQRFKRKDRMTYHVRSHEGGITKPYTCSVCGKGFSRPDHLSCHVKHVHSTERPFKCQTCTAAFATKDRLRTHMVRHEGKVSCNICGKLLSAAYITSHLKTHGQSQSINCNTCKQGISKTCMSEETSNQKQQQQQQQQQQQQQQQHVTSWPGKQVETLRLWEEAVKARKKEAANLCQTSTAATTPVTLTTPFNITSSVSSGTMSNPVTVAAAMSMRSPVNVSSAVNITSPMNIGHPVTITSPLAMTSPLTLTTPVNLPTPVTAPVNIAHPVTITSPMNLPTPMTLAAPLNIAMRPVESMPFLPQALPTSPPW", "length": 518 }, "evidence": [ { "id": "MGI:1313291", "url": "https://alliancegenome.org/gene/MGI:1313291#orthology", "database": "AGR" }, { "id": "HGNC:12949", "url": "https://alliancegenome.org/gene/HGNC:12949#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040108-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040108-4#orthology", "database": "AGR" }, { "id": "E7F042", "url": "https://omabrowser.org/oma/group/E7F042/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7F042", "url": "https://www.uniprot.org/uniprotkb/E7F042" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E7F042", "url": "https://www.uniprot.org/uniprotkb/E7F042" } ], "pmid": "" }, { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E7F042", "url": "https://www.uniprot.org/uniprotkb/E7F042" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E7F042", "url": "https://www.uniprot.org/uniprotkb/E7F042" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7F042", "url": "https://www.uniprot.org/uniprotkb/E7F042" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "E7F042", "url": "https://www.uniprot.org/uniprotkb/E7F042" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "E7F042", "url": "https://www.uniprot.org/uniprotkb/E7F042" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity", "id": "GO:0003700", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003700", "evidence": [ { "database": "UniProtKB", "id": "E7F042", "url": "https://www.uniprot.org/uniprotkb/E7F042" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 180, "end_pos": 182, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F042", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F042" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 93, "end_pos": 120, "start_aa": "Phe", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 384 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 180, "end_pos": 182 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 409, "end_pos": 411 }, { "start_pos": 416, "end_pos": 418 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"F1Q8N0_DANRE", "mass": { "chemical_mass": 29374.0, "monoisotopic_mass": 29374.0 }, "refseq": { "ac": "NP_956861", "name": "dehydrogenase/reductase SDR family member 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956861" }, "gene_names": [ { "name": "dhrs4", "type": "recommended", "evidence": [ { "id": "F1Q8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ] }, { "name": "dhrs2", "type": "synonym", "evidence": [ { "id": "NP_956861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956861" }, { "id": "F1Q8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ] }, { "name": "dhrs4", "type": "synonym", "evidence": [ { "id": "NP_956861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956861" } ] }, { "name": "zgc:65987", "type": "synonym", "evidence": [ { "id": "NP_956861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956861" }, { "id": "F1Q8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ] }, { "name": "zgc:77477", "type": "synonym", "evidence": [ { "id": "NP_956861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956861" }, { "id": "F1Q8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ] } ], "protein_names": [ { "name": "1.1.1.184", "type": "synonym", "evidence": [ { "id": "F1Q8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0/entry#names_and_taxonomy" } ] }, { "name": "Dehydrogenase/reductase SDR family member 4", "type": "synonym", "evidence": [ { "id": "F1Q8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0/entry#names_and_taxonomy" } ] }, { "name": "dehydrogenase/reductase (SDR family) member 2", "type": "synonym", "evidence": [ { "id": "NP_956861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956861" } ] }, { "name": "dehydrogenase/reductase SDR family member 4", "type": "synonym", "evidence": [ { "id": "NP_956861", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956861" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC066474.1, EH492207.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505373 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EB870011.1, EH451936.1 and EH518533.1. On Mar 14, 2013 this sequence version replaced NP_956861.1.", "evidence": [ { "database": "RefSeq", "id": "NP_956861", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956861" } ] }, { "annotation": "This locus represents the D. rerio DHRS4 gene, which is the ortholog of the human DHRS4 gene.", "evidence": [ { "database": "RefSeq", "id": "NP_956861", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956861" }, { "database": "PubMed", "id": "23036705", "url": "https://glygen.org/publication/PubMed/23036705" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q8N0", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dhrs4", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040426-1498", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1498", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000021135", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000021135", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd08936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd08936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "393539", "url": "https://www.ncbi.nlm.nih.gov/gene/393539", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002347", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002347", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020904", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020904", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:393539", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:393539", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WEVANVI", "url": "https://omabrowser.org/oma/group/WEVANVI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1Q8N0", "url": "https://www.orthodb.org/?gene=F1Q8N0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43943", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43943", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43943:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43943:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-5365859", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5365859", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_956861", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956861", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TX00", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TX00-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TX00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q8N0", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q8N0-1", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040426-1498", "url": "https://zfin.org/ZDB-GENE-040426-1498", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLKAITRCLWSNPVAGRRMMSHHISQNLSGKVAIVTASTDGIGLAAAEALGQRGAHVVVSSRRQTNVDKAVSLLRSKNIKVIGTTCNVGKAEDREKLINMTVEQCGGVDILVSNAAVNPFFGNILDSTEEVWDKILGVNVKASFLLTKMVVPHIEKRGGGSVVIVSSVAGYQPMPALGPYSVSKTALLGLTRALAPELAQSNIRVNCVAPGIIKTRFSSALWENEGVLEEFLKQTSIKRLGQPEEIGGVIAFLCSDEASYITGETITVTGGMNSRL", "length": 276, "header": "tr|F1Q8N0-1|F1Q8N0_DANRE Isoform 1 of Dehydrogenase/reductase SDR family member 4 OS=Danio rerio OX=7955 GN=dhrs4 PE=1 SV=1 CANONICAL=F1Q8N0-1" }, "isoforms": [ { "isoform_ac": "A0AB32TX00-1", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0/entry#A0AB32TX00-1", "sequence": { "sequence": "MLKAITRCLWSNPVAGRRMMSHHISQNLSGKVAIVTASTDGIGLAAAEALGQRGAHVVVSSRRQTNVDKAVSLLRSKNIKVIGTTCNVGKAEDREKLINMTVEQCGGVDILVSNAAVNPFFGNILDSTEEVWDKILGVNVKASFLLTKMVVPHIEKRGGGSVVIVSSVAGYQPMPALGPYSVSKTALLGLTRALAPELAQSNIRVNCVAPGIIKTRFSSAKYALTLVFSSCGKTRVCWKSS", "length": 241, "header": "tr|A0AB32TX00-1|F1Q8N0_DANRE Computationally mapped isoform of Dehydrogenase/reductase SDR family member 4 OS=Danio rerio OX=7955 GN=dhrs4 PE=1 SV=1 CANONICAL=F1Q8N0-1" }, "locus": {} }, { "isoform_ac": "F1Q8N0-1", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0/entry#F1Q8N0-1", "sequence": { "sequence": "MLKAITRCLWSNPVAGRRMMSHHISQNLSGKVAIVTASTDGIGLAAAEALGQRGAHVVVSSRRQTNVDKAVSLLRSKNIKVIGTTCNVGKAEDREKLINMTVEQCGGVDILVSNAAVNPFFGNILDSTEEVWDKILGVNVKASFLLTKMVVPHIEKRGGGSVVIVSSVAGYQPMPALGPYSVSKTALLGLTRALAPELAQSNIRVNCVAPGIIKTRFSSALWENEGVLEEFLKQTSIKRLGQPEEIGGVIAFLCSDEASYITGETITVTGGMNSRL", "length": 276, "header": "tr|F1Q8N0-1|F1Q8N0_DANRE Isoform 1 of Dehydrogenase/reductase SDR family member 4 OS=Danio rerio OX=7955 GN=dhrs4 PE=1 SV=1 CANONICAL=F1Q8N0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Molecular and functional evolution of human DHRS2 and DHRS4 duplicated genes.", "journal": "Gene", "date": "2012", "authors": "Gabrielli F, Tofanelli S", "evidence": [ { "database": "UniProtKB", "id": "F1Q8N0", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" }, { "database": "RefSeq", "id": "NP_956861", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956861" } ], "reference": [ { "type": "PubMed", "id": "23036705", "url": "https://glygen.org/publication/PubMed/23036705" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "F1Q8N0", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "F1Q8N0", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] }, { "title": "Therapeutic Silencing of Centromere Protein X Ameliorates Hyperglycemia in Zebrafish and Mouse Models of Type 2 Diabetes Mellitus.", "journal": "Front. Genet.", "date": "2019", "authors": "Zang Liqing, Shimada Yasuhito, Nakayama Hiroko, Chen Wenbiao, Okamoto Ayaka, Koide Hiroyuki, Oku Naoto, Dewa Takehisa, Shiota Masayuki, Nishimura Norihiro", "evidence": [ { "database": "UniProtKB", "id": "F1Q8N0", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ], "reference": [ { "type": "PubMed", "id": "31417608", "url": "https://glygen.org/publication/PubMed/31417608" } ] }, { "title": "Discovery of a genetic module essential for assigning left-right asymmetry in humans and ancestral vertebrates.", "journal": "Nat. Genet.", "date": "2022", "authors": "Szenker-Ravi E, Ott T, Khatoo M, de Bellaing AM, Goh WX, Chong YL, Beckers A, Kannesan D, Louvel G, Anujan P, Ravi V, Bonnard C, Moutton S, Schoen P, Fradin M, Colin E, Megarbane A, Daou L, Chehab G, Di Filippo S, Rooryck C, Deleuze JF, Boland A, Arribard N, Eker R, Tohari S, Ng AY, Rio M, Lim CT, Eisenhaber B, Eisenhaber F, Venkatesh B, Amiel J, Crollius HR, Gordon CT, Gossler A, Roy S, Attie-Bitach T, Blum M, Bouvagnet P, Reversade B", "evidence": [ { "database": "UniProtKB", "id": "F1Q8N0", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ], "reference": [ { "type": "PubMed", "id": "34903892", "url": "https://glygen.org/publication/PubMed/34903892" } ] }, { "title": "Insights Into the Peroxisomal Protein Inventory of Zebrafish.", "journal": "Front. Physiol.", "date": "2022", "authors": "Kamoshita Maki, Kumar Rechal, Anteghini Marco, Kunze Markus, Islinger Markus, Martins Dos Santos V\u00edtor, Schrader Michael", "evidence": [ { "database": "UniProtKB", "id": "F1Q8N0", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ], "reference": [ { "type": "PubMed", "id": "35295584", "url": "https://glygen.org/publication/PubMed/35295584" } ] } ], "pathway": [ { "id": "dre:393539", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:393539", "resource": "KEGG Pathway" }, { "id": "R-DRE-5365859", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5365859", "resource": "Reactome", "description": "RA biosynthesis pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZEZ3-1", "protein_name": "Dehydrogenase/reductase SDR family member 4", "gene_name": "Dhrs2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLSSMATIFRSIPRAFRGYLCAPVPLSARKFSQLTDENRTLAGKVAVVTGSTRGIGFAIARRMARDGAHVVISSRKQENVKEAVDILKEEGLSVTGTVCHVGKAEDRQHLVTTALKHSGGIDFLVCVAGVNPLVGSTLAASEQIWDKILDVNVKSPALLLSQVLPHMENRGGGCVVLVSSAVAYLPVPRLGVYNTSKTALLGLCKSLAVELAPKGIRVNCLAPGIIKTDFSLREETMPNMLPELKKVFGVQRLGEPEECAGLVSFLCSSDGSYITGENIVVGGFSPKL", "length": 289 }, "evidence": [ { "id": "FB:FBgn0035588", "url": "https://alliancegenome.org/gene/FB:FBgn0035588#orthology", "database": "AGR" }, { "id": "RGD:1583909", "url": "https://alliancegenome.org/gene/RGD:1583909#orthology", "database": "AGR" }, { "id": "HGNC:18349", "url": "https://alliancegenome.org/gene/HGNC:18349#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1498", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1498#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MZD5-1", "protein_name": "Dehydrogenase/reductase 4", "gene_name": "DHRS4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLKVGLPLGACARSWKSVRMASCGMARRNPLENKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDRAVATLKGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGVDILISNAAVSPFFGSLMDVPEEVWDKILDVNVKATALLTKAVVPEMAKRGGGSIVIVSSIAAYSPFPSLGPYNVSKTALLGLTKNLALELAESNVRVNCLAPGLIRTSFSRVLWEDPARQESIKATFQIKRIGKPEECAGIVSFLCSEDASYITGETVVVAGGSLSHL", "length": 279 }, "evidence": [ { "id": "F1Q8N0", "url": "https://omabrowser.org/oma/group/F1Q8N0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P0CG22-1", "protein_name": "Putative dehydrogenase/reductase SDR family member 4-like 1", "gene_name": "DHRS4L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHKARLRGHCARAGKSVRLASSGMTRRDPLTNKVALVTASTDWIGFAVAQRLAQDGAHVVVSRRKQQNVDQAVATLQGEGLSMTGTVCHVGKMKDWERLVATAMKLHGVIDILSLSITNSKRGLFWFTLLQTAEEAWDRNLDINGKALALMIKAVVPEMEKRGGGSVGFLASVAAFRPLPGFSPYNVSKTALLGLNKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDSLGIVSFLCSEDASYLTGETVMVGGGTPSRL", "length": 281 }, "evidence": [ { "id": "FB:FBgn0035588", "url": "https://alliancegenome.org/gene/FB:FBgn0035588#orthology", "database": "AGR" }, { "id": "HGNC:19732", "url": "https://alliancegenome.org/gene/HGNC:19732#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1498", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1498#orthology", "database": "AGR" }, { "id": "MGI:90169", "url": "https://alliancegenome.org/gene/MGI:90169#orthology", "database": "AGR" }, { "id": "RGD:708482", "url": "https://alliancegenome.org/gene/RGD:708482#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P32573-1", "protein_name": "Peroxisomal 2,4-dienoyl-CoA reductase SPS19 [(3E)-enoyl-CoA-producing]", "gene_name": "SPS19", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNTANTLDGKFVTEGSWRPDLFKGKVAFVTGGAGTICRVQTEALVLLGCKAAIVGRDQERTEQAAKGISQLAKDKDAVLAIANVDVRNFEQVENAVKKTVEKFGKIDFVIAGAAGNFVCDFANLSPNAFKSVVDIDLLGSFNTAKACLKELKKSKGSILFVSATFHYYGVPFQGHVGAAKAGIDALAKNLAVELGPLGIRSNCIAPGAIDNTEGLKRLAGKKYKEKALAKIPLQRLGSTRDIAESTVYIFSPAASYVTGTVLVVDGGMWHLGTYFGHELYPEALIKSMTSKL", "length": 292 }, "evidence": [ { "id": "FB:FBgn0035588", "url": "https://alliancegenome.org/gene/FB:FBgn0035588#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q13268-1", "protein_name": "Dehydrogenase/reductase SDR family member 2, mitochondrial", "gene_name": "DHRS2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSAVARGYQGWFHPCARLSVRMSSTGIDRKGVLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVVPGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGENIAVAGYSTRL", "length": 280 }, "evidence": [ { "id": "FB:FBgn0035588", "url": "https://alliancegenome.org/gene/FB:FBgn0035588#orthology", "database": "AGR" }, { "id": "RGD:1583909", "url": "https://alliancegenome.org/gene/RGD:1583909#orthology", "database": "AGR" }, { "id": "HGNC:18349", "url": "https://alliancegenome.org/gene/HGNC:18349#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1498", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1498#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PKH6-1", "protein_name": "Dehydrogenase/reductase SDR family member 4-like 2", "gene_name": "DHRS4L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQMARLLGLCAWARKSVRMASSRMTRRDPLTNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNCLHLDLSRLASAGCSGWTRKKRKA", "length": 232 }, "evidence": [ { "id": "FB:FBgn0035588", "url": "https://alliancegenome.org/gene/FB:FBgn0035588#orthology", "database": "AGR" }, { "id": "HGNC:19731", "url": "https://alliancegenome.org/gene/HGNC:19731#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1498", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1498#orthology", "database": "AGR" }, { "id": "MGI:90169", "url": "https://alliancegenome.org/gene/MGI:90169#orthology", "database": "AGR" }, { "id": "RGD:708482", "url": "https://alliancegenome.org/gene/RGD:708482#orthology", "database": "AGR" }, { "id": "F1Q8N0", "url": "https://omabrowser.org/oma/group/F1Q8N0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VID1-1", "protein_name": "Dehydrogenase/reductase SDR family member 4", "gene_name": "Dhrs4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQKAGLLLRGWTRAWKSVRMASSGLTRQNPLANKVALVTASTDGIGLAIARRLAEDGAHVVISSRKQQNVDRAVATLQGEGLSVTGVVCHVGKAEDREKLVNMALKLHQGIDILVSNAAVNPFFGNLMDVTEEVWNKVLSINVTASAMMIKAVVPAMEKRGGGSVVIVSSVAGFVLFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNCLAPGLIKTHFSSVLWKEKAREEMIKETMQIRRLGKPEDCVGIVSFLCSEDASYINGETVVVGGGTPSRL", "length": 279 }, "evidence": [ { "id": "FB:FBgn0035588", "url": "https://alliancegenome.org/gene/FB:FBgn0035588#orthology", "database": "AGR" }, { "id": "HGNC:16985", "url": "https://alliancegenome.org/gene/HGNC:16985#orthology", "database": "AGR" }, { "id": "HGNC:19732", "url": "https://alliancegenome.org/gene/HGNC:19732#orthology", "database": "AGR" }, { "id": "HGNC:19731", "url": "https://alliancegenome.org/gene/HGNC:19731#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1498", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1498#orthology", "database": "AGR" }, { "id": "MGI:90169", "url": "https://alliancegenome.org/gene/MGI:90169#orthology", "database": "AGR" }, { "id": "RGD:708482", "url": "https://alliancegenome.org/gene/RGD:708482#orthology", "database": "AGR" }, { "id": "F1Q8N0", "url": "https://omabrowser.org/oma/group/F1Q8N0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8WNV7-1", "protein_name": "Dehydrogenase/reductase SDR family member 4", "gene_name": "DHRS4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRAAGQLLRACSQTWKSVRMASTGVERRKPLENKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGTVCHVGKAEDRERLVAMAVNLHGGVDILVSNAAVNPFFGNIIDATEEVWDKILHVNVKATVLMTKAVVPEMEKRGGGSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNCLAPGLIKTNFSQVLWMDKARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDASYITGETVVVGGGTASRL", "length": 279 }, "evidence": [ { "id": "F1Q8N0", "url": "https://omabrowser.org/oma/group/F1Q8N0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q99LB2-1", "protein_name": "Dehydrogenase/reductase SDR family member 4", "gene_name": "Dhrs4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQKAGRLLGGWTQAWMSVRMASSGLTRRNPLSNKVALVTASTDGIGFAIARRLAEDGAHVVVSSRKQQNVDRAVATLQGEGLSVTGIVCHVGKAEDREKLITTALKRHQGIDILVSNAAVNPFFGNLMDVTEEVWDKVLSINVTATAMMIKAVVPEMEKRGGGSVVIVGSVAGFTRFPSLGPYNVSKTALLGLTKNFAAELAPKNIRVNCLAPGLIKTRFSSVLWEEKAREDFIKEAMQIRRLGKPEDCAGIVSFLCSEDASYINGETVVVGGGTPSRL", "length": 279 }, "evidence": [ { "id": "FB:FBgn0035588", "url": "https://alliancegenome.org/gene/FB:FBgn0035588#orthology", "database": "AGR" }, { "id": "HGNC:16985", "url": "https://alliancegenome.org/gene/HGNC:16985#orthology", "database": "AGR" }, { "id": "HGNC:19732", "url": "https://alliancegenome.org/gene/HGNC:19732#orthology", "database": "AGR" }, { "id": "HGNC:19731", "url": "https://alliancegenome.org/gene/HGNC:19731#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1498", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1498#orthology", "database": "AGR" }, { "id": "MGI:90169", "url": "https://alliancegenome.org/gene/MGI:90169#orthology", "database": "AGR" }, { "id": "RGD:708482", "url": "https://alliancegenome.org/gene/RGD:708482#orthology", "database": "AGR" }, { "id": "F1Q8N0", "url": "https://omabrowser.org/oma/group/F1Q8N0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BTZ2-1", "protein_name": "Dehydrogenase/reductase SDR family member 4", "gene_name": "DHRS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHKAGLLGLCARAWNSVRMASSGMTRRDPLANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGGTPSRL", "length": 278 }, "evidence": [ { "id": "FB:FBgn0035588", "url": "https://alliancegenome.org/gene/FB:FBgn0035588#orthology", "database": "AGR" }, { "id": "HGNC:16985", "url": "https://alliancegenome.org/gene/HGNC:16985#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1498", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1498#orthology", "database": "AGR" }, { "id": "MGI:90169", "url": "https://alliancegenome.org/gene/MGI:90169#orthology", "database": "AGR" }, { "id": "RGD:708482", "url": "https://alliancegenome.org/gene/RGD:708482#orthology", "database": "AGR" }, { "id": "F1Q8N0", "url": "https://omabrowser.org/oma/group/F1Q8N0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9S9W2-1", "protein_name": "Short-chain dehydrogenase/reductase SDRA", "gene_name": "SDRA", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEKKLPRRLEGKVAIVTASTQGIGFGITERFGLEGASVVVSSRKQANVDEAVAKLKSKGIDAYGIVCHVSNAQHRRNLVEKTVQKYGKIDIVVCNAAANPSTDPILSSKEAVLDKLWEINVKSSILLLQDMAPHLEKGSSVIFITSIAGFSPQGAMAMYGVTKTALLGLTKALAAEMAPDTRVNAVAPGFVPTHFASFITGSSEVREGIEEKTLLNRLGTTGDMAAAAAFLASDDSSYITGETLVVAGGMPSRL", "length": 254 }, "evidence": [ { "id": "F1Q8N0", "url": "https://omabrowser.org/oma/group/F1Q8N0/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VRJ4-1", "protein_name": "1.1.1.184", "gene_name": "Dhrs4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLHLSKQLVVRAPKIRLNASAVSGSGQSSSFDQNSNNYSRKLVGPNLNQCHKRLSSSSQSSTAGTMKRLAGKVAVVTASTDGIGFAIAKRLAEDGAAVVISSRKQKNVDSALAELRKLNLNVHGLKCHVSEPEDRKQLFEETISKFGKLNILVSNAATNPAVGGVLECDEKVWDKIFDVNVKSSYLLAKEALPLLRQQKNSSIVFVSSIAGYDAFELLGAYSVSKTALIGLTKAAAKDLAPEGIRVNCLAPGVIRTKFSKALYENESANEAALSKIPMGRLGTSEEMAGVVSFLVSEDAGYITGESIVAGGGMTARL", "length": 317 }, "evidence": [ { "id": "FB:FBgn0035588", "url": "https://alliancegenome.org/gene/FB:FBgn0035588#orthology", "database": "AGR" }, { "id": "RGD:1583909", "url": "https://alliancegenome.org/gene/RGD:1583909#orthology", "database": "AGR" }, { "id": "HGNC:18349", "url": "https://alliancegenome.org/gene/HGNC:18349#orthology", "database": "AGR" }, { "id": "HGNC:16985", "url": "https://alliancegenome.org/gene/HGNC:16985#orthology", "database": "AGR" }, { "id": "HGNC:19732", "url": "https://alliancegenome.org/gene/HGNC:19732#orthology", "database": "AGR" }, { "id": "HGNC:19731", "url": "https://alliancegenome.org/gene/HGNC:19731#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1498", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1498#orthology", "database": "AGR" }, { "id": "MGI:90169", "url": "https://alliancegenome.org/gene/MGI:90169#orthology", "database": "AGR" }, { "id": "RGD:708482", "url": "https://alliancegenome.org/gene/RGD:708482#orthology", "database": "AGR" }, { "id": "F1Q8N0", "url": "https://omabrowser.org/oma/group/F1Q8N0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "F1Q8N0", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ], "pmid": "" }, { "name": "carbonyl reductase (NADPH) activity", "id": "GO:0004090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004090", "evidence": [ { "database": "UniProtKB", "id": "F1Q8N0", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" }, { "start_pos": 99, "end_pos": 101, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DRE-5419165", "name": "RDH11,14,DHRS3,DRHS4 reduce atRAL to atROL", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol, endoplasmic reticulum membrane", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "F1Q8N0-1" ], "evidence": [ { "id": "R-DRE-5419165", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5419165" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "F1Q8N0", "gene_name": "dhrs4", "activity": [ { "ec_number": "1.1.1.184", "activity": "a secondary alcohol + NADP(+) = a ketone + NADPH + H(+).", "evidence": [ { "id": "F1Q8N0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q8N0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.1.1.184", "ec_name": "a secondary alcohol + NADP(+) = a ketone + NADPH + H(+).", "evidence": [ { "id": "1.1.1.184", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.184" }, { "id": "1.1.1.184", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.1.184" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 }, { "start_pos": 99, "end_pos": 101 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F593-1", "uniprot_ac": "E7F593", "uniprot_id": "E7F593_DANRE", "mass": { "chemical_mass": 28274.0, "monoisotopic_mass": 28274.0 }, "refseq": { "ac": "NP_001313643", "name": "testis-expressed protein 47", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313643" }, "gene_names": [ { "name": "tex47", "type": "recommended", "evidence": [ { "id": "E7F593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F593" } ] }, { "name": "c12h7orf62", "type": "synonym", "evidence": [ { "id": "NP_001313643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313643" }, { "id": "E7F593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F593" } ] }, { "name": "tex47", "type": "synonym", "evidence": [ { "id": "NP_001313643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313643" } ] } ], "protein_names": [ { "name": "Testis-expressed protein 47", "type": "synonym", "evidence": [ { "id": "E7F593", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F593/entry#names_and_taxonomy" } ] }, { "name": "testis-expressed protein 47", "type": "synonym", "evidence": [ { "id": "NP_001313643", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313643" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQQ01033434.1, SRR32588723.2728984.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476808 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000012.1. On Jun 25, 2025 this sequence version replaced NP_001313643.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001313643", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313643" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F593", "url": "https://www.uniprot.org/uniprotkb/E7F593" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tex47", "url": "https://www.uniprot.org/uniprotkb/E7F593", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-240222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-240222-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000053520", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000053520", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100006770", "url": "https://www.ncbi.nlm.nih.gov/gene/100006770", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR055308", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055308", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100006770", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006770", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MDSERTW", "url": "https://omabrowser.org/oma/group/MDSERTW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3B1Y2", "url": "https://www.orthodb.org/?gene=A0A8M3B1Y2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F593", "url": "https://www.orthodb.org/?gene=E7F593", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR34035", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34035", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR34035:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR34035:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24787", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24787", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001313643", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313643", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3B1Y2", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B1Y2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B1Y2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B1Y2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TYC1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TYC1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TYC1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TYC1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUF4", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUF4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUF4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUF4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUF6", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUF6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUF9", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUF9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUG3", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUG3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUG6", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUG6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUG7", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUG7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUG9", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUG9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GUG9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GUG9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F593", "url": "https://www.uniprot.org/uniprotkb/E7F593", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F593-1", "url": "https://www.uniprot.org/uniprotkb/E7F593-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-240222-1", "url": "https://zfin.org/ZDB-GENE-240222-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEKDASGDSENGSSLFHHRLRARRRTQADSQPKFLLHRLVVAARLSCTPEDRSTVAAHYEKLNMSIQRSRPGEELTGLLLLYPQHTLLVIECSTEALLSVLQDLRHMEENPDSSLILHPRILLVSHDLPCRLFPQWFCMMLSESESRRTEASDEQNPEKLLNQTMKQLLQLGCHLYNTQHNTGSTMLTPDEVLKDVSDVVPPVAAVYRLLQMEALLSPARYISTYHSPIHQPLDSESVWPAVEHLRII", "length": 248, "header": "tr|E7F593-1|E7F593_DANRE Isoform 1 of Testis-expressed protein 47 OS=Danio rerio OX=7955 GN=tex47 PE=4 SV=3 CANONICAL=E7F593-1" }, "isoforms": [ { "isoform_ac": "A0A8M3B1Y2-1", "url": "https://www.uniprot.org/uniprotkb/E7F593/entry#A0A8M3B1Y2-1", "sequence": { "sequence": "MEKDASGDSENGSSLFHHRLRARRRTQADSQPKFLLHRLVVAARLSCTPEDRSTVAAHYEKLNMSIQRSRPGEELTGLLLLYPQHTLLVIECSTEALLSVLQDLRHMEENPHSSLILHPRILLVSHDLPCRLFPQWFCMMLSESESRRTEASDEQNPEKLLNQTMKRLLQLGCHLYNTQHNTGSTMLTPDEVLKDVSDVVPPVAAVYRLLQMEALLSPARYISTYHSPIHQPLDSGHVFSSFRPFSV", "length": 247, "header": "tr|A0A8M3B1Y2-1|E7F593_DANRE Computationally mapped isoform of Testis-expressed protein 47 OS=Danio rerio OX=7955 GN=tex47 PE=4 SV=2 CANONICAL=E7F593-1" }, "locus": {} }, { "isoform_ac": "A0AB32TYC1-1", "url": "https://www.uniprot.org/uniprotkb/E7F593/entry#A0AB32TYC1-1", "sequence": { "sequence": "MEKDASGDSENGSSLFHHRLRARRRTQADSQPKFLLHRLVVAARLSCTPEDRSTVAAHYEKLNMSIQRSRPGEELTGLLLLYPQHTLLVIECSTEALLSVLQDLRHMEENPHSLILHPRILLVSHDLPCRLFPQWFCMMLSESESRRTEASDEQNPEKLLNQTMKRLLQLGCHLYNTQHNTGSTMLTPDEVLKDVSDVVPPVAAVYRLLQMEALLSPARYISTYHSPIHQPLDSESVWPAVEHLRIA", "length": 247, "header": "tr|A0AB32TYC1-1|E7F593_DANRE Computationally mapped isoform of Testis-expressed protein 47 OS=Danio rerio OX=7955 GN=tex47 PE=4 SV=2 CANONICAL=E7F593-1" }, "locus": {} }, { "isoform_ac": "A0AC58GUF4-1", "url": "https://www.uniprot.org/uniprotkb/E7F593/entry#A0AC58GUF4-1", "sequence": { "sequence": "MSIQRSRPGEELTGLLLLYPQHTLLVIECSTEALLSVLQDLRHMEENPHSSLILHPRILLVSHDLPCRLFPQWFCMMLSESESRRTEASDEQNPEKLLNQTMKRLLQLGCHLYNTQHNTGSTMLTPDEVLKDVSDVVPPVAAVYRLLQMEALLSPARYISTYHSPIHQPLDSESVWPAVEHLRIA", "length": 185, "header": "tr|A0AC58GUF4-1|A0AC58GUF4_DANRE Computationally mapped isoform of Testis-expressed protein 47 isoform X8 OS=Danio rerio OX=7955 GN=tex47 PE=4 SV=1 CANONICAL=E7F593-1" }, "locus": {} }, { "isoform_ac": "A0AC58GUF6-1", "url": "https://www.uniprot.org/uniprotkb/E7F593/entry#A0AC58GUF6-1", "sequence": { "sequence": "MEKDASGDSENGSSLFHHRLRARRRTQADSQPKFLLHRLVVAARLSCTPEDRSTVAAHYEKLNMSIQRSRPGEELTGLLLLYPQHTLLVIECSTEALLSVLQDLRHMEENPHSSLILHPRILLVSHDLPCRLFPQWFCMMLSESESRRTEASDEQNPEKLLNQTMKRLLQLGCHLYNTQHNTVHTLHTHSHGTITSFKVLKLLIFSVILYRS", "length": 212, "header": "tr|A0AC58GUF6-1|A0AC58GUF6_DANRE Computationally mapped isoform of Testis-expressed protein 47 isoform X7 OS=Danio rerio OX=7955 GN=tex47 PE=4 SV=1 CANONICAL=E7F593-1" }, "locus": {} }, { "isoform_ac": "A0AC58GUF9-1", "url": "https://www.uniprot.org/uniprotkb/E7F593/entry#A0AC58GUF9-1", "sequence": { "sequence": "MEKDASGDSENGSSLFHHRLRARRRTQADSQPKFLLHRLVVAARLSCTPEDRSTVAAHYEKLNMSIQRSRPGEELTGLLLLYPQHTLLVIECSTEALLSVLQDLRHMEENPHRLFPQWFCMMLSESESRRTEASDEQNPEKLLNQTMKRLLQLGCHLYNTQHNTGSTMLTPDEVLKDVSDVVPPVAAVYRLLQMEALLSPARYISTYHSPIHQPLDSGHVFSSFRPFSV", "length": 229, "header": "tr|A0AC58GUF9-1|A0AC58GUF9_DANRE Computationally mapped isoform of Testis-expressed protein 47 isoform X6 OS=Danio rerio OX=7955 GN=tex47 PE=4 SV=1 CANONICAL=E7F593-1" }, "locus": {} }, { "isoform_ac": "A0AC58GUG3-1", "url": "https://www.uniprot.org/uniprotkb/E7F593/entry#A0AC58GUG3-1", "sequence": { "sequence": "MEKDASGDSENGSSLFHHRLRARRRTQADSQPKFLLHRLVVAARLSCTPEDRSTVAAHYEKLNMSIQRSRPGEELTGLLLLYPQHTLLVIECSTEALLSVLQDLRHMEENPHRLFPQWFCMMLSESESRRTEASDEQNPEKLLNQTMKRLLQLGCHLYNTQHNTGSTMLTPDEVLKDVSDVVPPVAAVYRLLQMEALLSPARYISTYHSPIHQPLDSESVWPAVEHLRIA", "length": 230, "header": "tr|A0AC58GUG3-1|A0AC58GUG3_DANRE Computationally mapped isoform of Testis-expressed protein 47 isoform X5 OS=Danio rerio OX=7955 GN=tex47 PE=4 SV=1 CANONICAL=E7F593-1" }, "locus": {} }, { "isoform_ac": "A0AC58GUG6-1", "url": "https://www.uniprot.org/uniprotkb/E7F593/entry#A0AC58GUG6-1", "sequence": { "sequence": "MEKDASGDSENGSSLFHHRLRARRRTQADSQPKFLLHRLVVAARLSCTPEDRSTVAAHYEKLNMSIQRSRPGEELTGLLLLYPQHTLLVIECSTEALLSVLQDLRHMEENPHSSLILHPRILLVSHDLPCRLFPQWFCMMLSESESRRTEASDEQNPEKLLNQTMKRLLQLGCHLYNTQHNTGSTMLTPDEVLKDVSDVVPPVAAVYRLLQMEALLSPARYISTYHSPIHQPLDSAG", "length": 237, "header": "tr|A0AC58GUG6-1|A0AC58GUG6_DANRE Computationally mapped isoform of Testis-expressed protein 47 isoform X4 OS=Danio rerio OX=7955 GN=tex47 PE=4 SV=1 CANONICAL=E7F593-1" }, "locus": {} }, { "isoform_ac": "A0AC58GUG7-1", "url": "https://www.uniprot.org/uniprotkb/E7F593/entry#A0AC58GUG7-1", "sequence": { "sequence": "MEKDASGDSENGSSLFHHRLRARRRTQADSQPKFLLHRLVVAARLSCTPEDRSTVAAHYEKLNMSIQRSRPGEELTGLLLLYPQHTLLVIECSTEALLSVLQDLRHMEENPHSLILHPRILLVSHDLPCRLFPQWFCMMLSESESRRTEASDEQNPEKLLNQTMKRLLQLGCHLYNTQHNTGSTMLTPDEVLKDVSDVVPPVAAVYRLLQMEALLSPARYISTYHSPIHQPLDSGHVFSSFRPFSV", "length": 246, "header": "tr|A0AC58GUG7-1|A0AC58GUG7_DANRE Computationally mapped isoform of Testis-expressed protein 47 isoform X3 OS=Danio rerio OX=7955 GN=tex47 PE=4 SV=1 CANONICAL=E7F593-1" }, "locus": {} }, { "isoform_ac": "A0AC58GUG9-1", "url": "https://www.uniprot.org/uniprotkb/E7F593/entry#A0AC58GUG9-1", "sequence": { "sequence": "MSIQRSRPGEELTGLLLLYPQHTLLVIECSTEALLSVLQDLRHMEENPHSLILHPRILLVSHDLPCRLFPQWFCMMLSESESRRTEASDEQNPEKLLNQTMKRLLQLGCHLYNTQHNTGSTMLTPDEVLKDVSDVVPPVAAVYRLLQMEALLSPARYISTYHSPIHQPLDSGHVFSSFRPFSV", "length": 183, "header": "tr|A0AC58GUG9-1|A0AC58GUG9_DANRE Computationally mapped isoform of Testis-expressed protein 47 isoform X9 OS=Danio rerio OX=7955 GN=tex47 PE=4 SV=1 CANONICAL=E7F593-1" }, "locus": {} }, { "isoform_ac": "E7F593-1", "url": "https://www.uniprot.org/uniprotkb/E7F593/entry#E7F593-1", "sequence": { "sequence": "MEKDASGDSENGSSLFHHRLRARRRTQADSQPKFLLHRLVVAARLSCTPEDRSTVAAHYEKLNMSIQRSRPGEELTGLLLLYPQHTLLVIECSTEALLSVLQDLRHMEENPDSSLILHPRILLVSHDLPCRLFPQWFCMMLSESESRRTEASDEQNPEKLLNQTMKQLLQLGCHLYNTQHNTGSTMLTPDEVLKDVSDVVPPVAAVYRLLQMEALLSPARYISTYHSPIHQPLDSESVWPAVEHLRII", "length": 248, "header": "tr|E7F593-1|E7F593_DANRE Isoform 1 of Testis-expressed protein 47 OS=Danio rerio OX=7955 GN=tex47 PE=4 SV=3 CANONICAL=E7F593-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Discovery of a genetic module essential for assigning left-right asymmetry in humans and ancestral vertebrates.", "journal": "Nat. Genet.", "date": "2022", "authors": "Szenker-Ravi E, Ott T, Khatoo M, de Bellaing AM, Goh WX, Chong YL, Beckers A, Kannesan D, Louvel G, Anujan P, Ravi V, Bonnard C, Moutton S, Schoen P, Fradin M, Colin E, Megarbane A, Daou L, Chehab G, Di Filippo S, Rooryck C, Deleuze JF, Boland A, Arribard N, Eker R, Tohari S, Ng AY, Rio M, Lim CT, Eisenhaber B, Eisenhaber F, Venkatesh B, Amiel J, Crollius HR, Gordon CT, Gossler A, Roy S, Attie-Bitach T, Blum M, Bouvagnet P, Reversade B", "evidence": [ { "database": "UniProtKB", "id": "E7F593", "url": "https://www.uniprot.org/uniprotkb/E7F593" } ], "reference": [ { "type": "PubMed", "id": "34903892", "url": "https://glygen.org/publication/PubMed/34903892" } ] } ], "pathway": [ { "id": "dre:100006770", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006770", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0JPP5-1", "protein_name": "Testis-expressed protein 47", "gene_name": "Tex47", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFIVHNRRSSKKQFQVDPLLMPKVPRINYLHIQEEKHRLQLKKFLLHRLFLVGYIQANTEKKEISEYYEQLFQSILKHHLGEVVTGLFLIYPSSFLHILESSNGTLFRILLDYVAHEKSEREFMIQNMKIIVASHNIPTRLFMQWHISIIKVPVLYLDDDTQSQSVEEVTTDFLTLTHKLALHLYKTVKLGGKGPGDNLHQLAPELILPEKTIKYLCKATEFMDPASFLSMYNRPIHITMDSDIVWPAPSRF", "length": 253 }, "evidence": [ { "id": "RGD:1564345", "url": "https://alliancegenome.org/gene/RGD:1564345#orthology", "database": "AGR" }, { "id": "MGI:1918170", "url": "https://alliancegenome.org/gene/MGI:1918170#orthology", "database": "AGR" }, { "id": "HGNC:22402", "url": "https://alliancegenome.org/gene/HGNC:22402#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-240222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-240222-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8TBZ9-1", "protein_name": "Testis-expressed protein 47", "gene_name": "TEX47", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFSVHNQKGSKRPLPLEPLLFLQVPRSNYLHFQEEKQRLHLKKFLLDRMFLVAKIQANVERKDVADYYEQMFQSVLKHHLGEAVTGLLLIYPTSILHILESSSDTLYKVLLDYIGHVKDETVFFIQQMKIIVISHNIPMRLFMQWHVSVIKVPVMYLDDVTQSQSLKEVITDFLTQTHKLSLYLCQTMKVGTKGPGDNLHQVAPDLLLPEQIIKYLCKSEEFMDPATFINMYNRPIHITLDSEVVWPAPSRF", "length": 253 }, "evidence": [ { "id": "RGD:1564345", "url": "https://alliancegenome.org/gene/RGD:1564345#orthology", "database": "AGR" }, { "id": "MGI:1918170", "url": "https://alliancegenome.org/gene/MGI:1918170#orthology", "database": "AGR" }, { "id": "HGNC:22402", "url": "https://alliancegenome.org/gene/HGNC:22402#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-240222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-240222-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D5W8-1", "protein_name": "Testis-expressed protein 47", "gene_name": "Tex47", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFMVHNRKGSKKQFQVDPLLLPKVPRTNYLHLQEEKHRLQLKKFLLHRMFLVGYIQGNTEKKDISEYYEQLFQSILKHHLGESVTGLMLIYPSTFLHILESSNGTLFRILLDYVAHEKSETEFMLQNMKIVVASHNIPTRLFMQWHISAIKVPVLYLDDESQSPSIEEVTTEFLTMTHKLALQLYKTVKLGAKGPGDNLHQLAPELILPEQIIKYLCKAEEFMDPASFLSMYNRPIHVTLDSDIVWPAPSRF", "length": 253 }, "evidence": [ { "id": "RGD:1564345", "url": "https://alliancegenome.org/gene/RGD:1564345#orthology", "database": "AGR" }, { "id": "MGI:1918170", "url": "https://alliancegenome.org/gene/MGI:1918170#orthology", "database": "AGR" }, { "id": "HGNC:22402", "url": "https://alliancegenome.org/gene/HGNC:22402#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-240222-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-240222-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 162, "end_pos": 164, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 162, "end_pos": 164 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F481-1", "uniprot_ac": "E7F481", "uniprot_id": "E7F481_DANRE", "mass": { "chemical_mass": 33056.0, "monoisotopic_mass": 33056.0 }, "refseq": { "ac": "XP_002667664", "name": "SLAM family member 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667664" }, "gene_names": [ { "name": "si:cabz01074946.1", "type": "recommended", "evidence": [ { "id": "E7F481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F481" } ] }, { "name": "si:cabz01074946.1", "type": "synonym", "evidence": [ { "id": "XP_002667664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667664" } ] } ], "protein_names": [ { "name": "SLAM family member 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002667664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667664" }, { "id": "E7F481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F481/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002667664.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_002667664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667664" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F481", "url": "https://www.uniprot.org/uniprotkb/E7F481" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:cabz01074946.1", "url": "https://www.uniprot.org/uniprotkb/E7F481", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-160113-134", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-160113-134", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000090396", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000090396", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100331505", "url": "https://www.ncbi.nlm.nih.gov/gene/100331505", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015631", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015631", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100331505", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331505", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WIATYNN", "url": "https://omabrowser.org/oma/group/WIATYNN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F481", "url": "https://www.orthodb.org/?gene=E7F481", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12080", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12080", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12080:SF59", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12080:SF59", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002667664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667664", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TZ06", "url": "https://www.uniprot.org/uniprotkb/A0AB32TZ06", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TZ06-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TZ06-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F481", "url": "https://www.uniprot.org/uniprotkb/E7F481", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F481-1", "url": "https://www.uniprot.org/uniprotkb/E7F481-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-160113-134", "url": "https://zfin.org/ZDB-GENE-160113-134", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSLYTVVLVCIIYNNQVFGREERVTVYLGQSALLKTGSDRPWNLTRVQWSIYKNTTYIASLRDRIVTIFDFWRYRDRLELNSNTGDLTIKDVRMDDTLTYTVDLVNADGTRPQHKVHLTVKERLEKPKIHKMLYSLSDGQCHVALNCTVPGRNVILSWTPDGYFNGSYLSGNPTSTNPLSVVFISFRGTGNVTFNCTASSQEQVESTLMTVGCSENPQMCEVCSFCRPCSTGGFCVLCYIVLTAVLVVFAYKNKERIKDFCMNGPVQFIQNRWSPSAPAHSSESAPAPSLKTCT", "length": 294, "header": "tr|E7F481-1|E7F481_DANRE Isoform 1 of SLAM family member 5 isoform X1 OS=Danio rerio OX=7955 GN=si:cabz01074946.1 PE=4 SV=1 CANONICAL=E7F481-1" }, "isoforms": [ { "isoform_ac": "A0AB32TZ06-1", "url": "https://www.uniprot.org/uniprotkb/E7F481/entry#A0AB32TZ06-1", "sequence": { "sequence": "MSLYTVVLVCIIYNNQVFGREERVTVYLGQSALLKTGSDRPWNLTRVQWSIYKNTTYIASLRDRIVTIFDFWRYRDRLELNSNTGDLTIKDVRMDDTLTYTVDLVNADGTRPQHKVHLTVKERLEKPKIHKMLYSLSDGQCHVALNCTVPGRNVILSWTPDGYFNGSYLSGNPTSTNPLSVVFISFRGTGNVTFNCTASSQEQVESTLMTVGCSENPQMCEVCSFCRPCSTGGFCVLCYIVLTAVLVVFAYKNKERIKDFCMNGPVQFIQNR", "length": 272, "header": "tr|A0AB32TZ06-1|E7F481_DANRE Computationally mapped isoform of SLAM family member 5 isoform X1 OS=Danio rerio OX=7955 GN=si:cabz01074946.1 PE=4 SV=1 CANONICAL=E7F481-1" }, "locus": {} }, { "isoform_ac": "E7F481-1", "url": "https://www.uniprot.org/uniprotkb/E7F481/entry#E7F481-1", "sequence": { "sequence": "MSLYTVVLVCIIYNNQVFGREERVTVYLGQSALLKTGSDRPWNLTRVQWSIYKNTTYIASLRDRIVTIFDFWRYRDRLELNSNTGDLTIKDVRMDDTLTYTVDLVNADGTRPQHKVHLTVKERLEKPKIHKMLYSLSDGQCHVALNCTVPGRNVILSWTPDGYFNGSYLSGNPTSTNPLSVVFISFRGTGNVTFNCTASSQEQVESTLMTVGCSENPQMCEVCSFCRPCSTGGFCVLCYIVLTAVLVVFAYKNKERIKDFCMNGPVQFIQNRWSPSAPAHSSESAPAPSLKTCT", "length": 294, "header": "tr|E7F481-1|E7F481_DANRE Isoform 1 of SLAM family member 5 isoform X1 OS=Danio rerio OX=7955 GN=si:cabz01074946.1 PE=4 SV=1 CANONICAL=E7F481-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100331505", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331505", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7F481", "url": "https://www.uniprot.org/uniprotkb/E7F481" } ], "pmid": "" }, { "name": "cell-cell junction", "id": "GO:0005911", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005911", "evidence": [ { "database": "UniProtKB", "id": "E7F481", "url": "https://www.uniprot.org/uniprotkb/E7F481" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "E7F481", "url": "https://www.uniprot.org/uniprotkb/E7F481" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 165, "end_pos": 167, "annotation": "n_glycosylation_sequon" }, { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 195, "end_pos": 197, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F481", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F481" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ig-like", "eco_id": "ECO_0000259", "start_pos": 127, "end_pos": 212, "start_aa": "Pro", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 146, "end_pos": 148 }, { "start_pos": 165, "end_pos": 167 }, { "start_pos": 191, "end_pos": 193 }, { "start_pos": 195, "end_pos": 197 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 54, "end_pos": 56 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F0N6-1", "uniprot_ac": "E7F0N6", "uniprot_id": "E7F0N6_DANRE", "mass": { "chemical_mass": 78994.0, "monoisotopic_mass": 78994.0 }, "refseq": { "ac": "XP_003199365", "name": "amyloid beta precursor protein binding family B member 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199365" }, "gene_names": [ { "name": "apbb1", "type": "recommended", "evidence": [ { "id": "E7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0N6" } ] }, { "name": "apbb1", "type": "synonym", "evidence": [ { "id": "XP_003199365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199365" } ] } ], "protein_names": [ { "name": "Amyloid beta precursor protein binding family B member 1 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0N6/entry#names_and_taxonomy" } ] }, { "name": "amyloid beta precursor protein binding family B member 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003199365", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199365" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003199365.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003199365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199365" } ] } ], "disease": [ { "disease_id": "DOID:0050742", "recommended_name": { "id": "DOID:0050742", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050742", "name": "nicotine dependence", "description": "A substance dependence that is characterized by a physical dependence on nicotine." }, "synonyms": [ { "id": "DOID:0050742", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050742", "name": "tobacco use disorder", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050742", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050742" } ] }, { "disease_id": "DOID:10652", "recommended_name": { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid." }, "synonyms": [ { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer disease", "description": "" }, { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimers dementia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F0N6", "url": "https://www.uniprot.org/uniprotkb/E7F0N6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "apbb1", "url": "https://www.uniprot.org/uniprotkb/E7F0N6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091118-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-127", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000076560", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000076560", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00201", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00201", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01271", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01271", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd01272", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01272", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "565164", "url": "https://www.ncbi.nlm.nih.gov/gene/565164", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001202", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001202", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565164", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565164", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ELCNGEH", "url": "https://omabrowser.org/oma/group/ELCNGEH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F0N6", "url": "https://www.orthodb.org/?gene=E7F0N6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14058", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14058", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14058:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14058:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00397", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00397", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003199365", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003199365", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32U146", "url": "https://www.uniprot.org/uniprotkb/A0AB32U146", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U146-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32U146-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0N6", "url": "https://www.uniprot.org/uniprotkb/E7F0N6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0N6-1", "url": "https://www.uniprot.org/uniprotkb/E7F0N6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091118-127", "url": "https://zfin.org/ZDB-GENE-091118-127", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSVKSPSDVLNENAYISSSLTLDLCLSHEKKLVLNDTSGSQKSRHNYSSTTSIQLLKDIMGGLDDDDDASLRHQEGEWSRNQENEHSLSESKTKWMKDDKNQICKLAEQQQQQDQNLNLVENKNESTETNPNQNSQRHHEEKNKTLNALCSDLNDWGADESVLIYSSVMMEKNQEESRGVDVEGEEEENVDPSGGENRDSSEIQKKRAEGSGRNTCLLFSKNGIPSDEDSSCMSLSQGSTASSTPDGEPESYWDGSAFETDTDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPETLEERPSSASPAVTPADEPQIAWNDVSHQNTFSGDELWQTEVVSSDESLKEFEGATLRYASINLSFSQTEEEEEQTCFSSIEGSKCFAVRSLGWVEITEEEMAPGRSSVAVNNCIRQLSYQKHNLDDTAGIWGEGKEMLLVLENEMLNLFEPHGQTLLHSQPIVSIRVWGVGRDDGRDFAYVARDKLTHVLKCHVFRCDTPAKNIATSMHEICSKIMAQRKSSSRLNSDPSRLRDIPFQEFPVPKNELVQRFQVRYLGRVQVTKPVGMEVINVALETALNKDKEDWTPVTVNVASATLTVLTSETEEVLSECRVRFLSFMGVGKDVHTFAFIMAEGPGDFICHMFWCDPNAASLSEAVQAACMLRYQKCLDARPPISGSSCLPGPPADSVARRVGSSVKKGVQSLLGSFKRSGSQTP", "length": 710, "header": "tr|E7F0N6-1|E7F0N6_DANRE Isoform 1 of Amyloid beta precursor protein binding family B member 1 isoform X1 OS=Danio rerio OX=7955 GN=apbb1 PE=4 SV=1 CANONICAL=E7F0N6-1" }, "isoforms": [ { "isoform_ac": "A0AB32U146-1", "url": "https://www.uniprot.org/uniprotkb/E7F0N6/entry#A0AB32U146-1", "sequence": { "sequence": "MSVKSPSDVLNENAYISSSLTLDLCLSHEKKLVLNDTSGSQKSRHNYSSTTSIQLLKDIMGGLDDDDDASLRHQEGEWSRNQENEHSLSESKTKWMKDDKNQICKLAEQQQQQDQNLNLVENKNESTETNPNQNSQRHHEEKNKTLNALCSDLNDWGADESVLIYSSVMMEKNQEESRGVDVEGEEEENVDPSGGENRDSSEIQKKRAEGSGRNTCLLFSKNGIPSDEDSSCMSLSQGSTASSTPDGEPESYWDGSAFETDTDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPETLEERPSSASPAVTPADEPQTEVVSSDESLKEFEGATLRYASINLSFSQTEEEEEQTCFSSIEGSKCFAVRSLGWVEITEEEMAPGRSSVAVNNCIRQLSYQKHNLDDTAGIWGEGKEMLLVLENEMLNLFEPHGQTLLHSQPIVSIRVWGVGRDDGRDFAYVARDKLTHVLKCHVFRCDTPAKNIATSMHEICSKIMAQRKSSSRLNSDPSRLRDIPFQEFPVPKNELVQRFQVRYLGRVQVTKPVGMEVINVALETALNKDKEDWTPVTVNVASATLTVLTSETEEVLSECRVRFLSFMGVGKDVHTFAFIMAEGPGDFICHMFWCDPNAASLSEAVQAACMLRYQKCLDARPPISGSSCLPGPPADSVARRVGSSVKKGVQSLLGSFKRSGSQTP", "length": 691, "header": "tr|A0AB32U146-1|E7F0N6_DANRE Computationally mapped isoform of Amyloid beta precursor protein binding family B member 1 isoform X1 OS=Danio rerio OX=7955 GN=apbb1 PE=4 SV=1 CANONICAL=E7F0N6-1" }, "locus": {} }, { "isoform_ac": "E7F0N6-1", "url": "https://www.uniprot.org/uniprotkb/E7F0N6/entry#E7F0N6-1", "sequence": { "sequence": "MSVKSPSDVLNENAYISSSLTLDLCLSHEKKLVLNDTSGSQKSRHNYSSTTSIQLLKDIMGGLDDDDDASLRHQEGEWSRNQENEHSLSESKTKWMKDDKNQICKLAEQQQQQDQNLNLVENKNESTETNPNQNSQRHHEEKNKTLNALCSDLNDWGADESVLIYSSVMMEKNQEESRGVDVEGEEEENVDPSGGENRDSSEIQKKRAEGSGRNTCLLFSKNGIPSDEDSSCMSLSQGSTASSTPDGEPESYWDGSAFETDTDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPETLEERPSSASPAVTPADEPQIAWNDVSHQNTFSGDELWQTEVVSSDESLKEFEGATLRYASINLSFSQTEEEEEQTCFSSIEGSKCFAVRSLGWVEITEEEMAPGRSSVAVNNCIRQLSYQKHNLDDTAGIWGEGKEMLLVLENEMLNLFEPHGQTLLHSQPIVSIRVWGVGRDDGRDFAYVARDKLTHVLKCHVFRCDTPAKNIATSMHEICSKIMAQRKSSSRLNSDPSRLRDIPFQEFPVPKNELVQRFQVRYLGRVQVTKPVGMEVINVALETALNKDKEDWTPVTVNVASATLTVLTSETEEVLSECRVRFLSFMGVGKDVHTFAFIMAEGPGDFICHMFWCDPNAASLSEAVQAACMLRYQKCLDARPPISGSSCLPGPPADSVARRVGSSVKKGVQSLLGSFKRSGSQTP", "length": 710, "header": "tr|E7F0N6-1|E7F0N6_DANRE Isoform 1 of Amyloid beta precursor protein binding family B member 1 isoform X1 OS=Danio rerio OX=7955 GN=apbb1 PE=4 SV=1 CANONICAL=E7F0N6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 307, "start_aa": "Thr", "end_pos": 307, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr307", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:565164", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565164", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O00213-1", "protein_name": "Amyloid beta precursor protein binding family B member 1", "gene_name": "APBB1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVPSSLSQSAINANSHGGPALSLPLPLHAAHNQLLNAKLQATAVGPKDLRSAMGEGGGPEPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQEPEMAPLGPKGLIHLYSELELSAHNAANRGLRGPGLIISTQEQGPDEGEEKAAGEAEEEEEDDDDEEEEEDLSSPPGLPEPLESVEAPPRPQALTDGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQLTWTGFAHGEGFEDGEFWKDEPSDEAPMELGLKEPEEGTLTFPAQSLSPEPLPQEEEKLPPRNTNPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGKDLLLQLEDETLKLVEPQSQALLHAQPIISIRVWGVGRDSGRERDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMAERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCLDARSQASTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGAHTP", "length": 710 }, "evidence": [ { "id": "HGNC:581", "url": "https://alliancegenome.org/gene/HGNC:581#orthology", "database": "AGR" }, { "id": "MGI:107765", "url": "https://alliancegenome.org/gene/MGI:107765#orthology", "database": "AGR" }, { "id": "RGD:2122", "url": "https://alliancegenome.org/gene/RGD:2122#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091118-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-127#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P46933-1", "protein_name": "Amyloid beta precursor protein binding family B member 1", "gene_name": "Apbb1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVPSSLSQSAINANSHGGPALSFPFPLHAAHNQLLNAKLQATAVVPKDLRSAMGEGSVPEPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQEAETAPLGPKGLMHLYSELELSAHNAANRGLHGSALIINTQGLGPDEGEEKAAGEVEEEDEDEEEEDEEEEDLSSPQGLPEPLENVEVPSGPQVLTDGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGNSPQEESQLTWTGFAHQEGFEEGEFWKDEPSEEAPMELGLKDPEEGTLPFSAQSLSPEPVPQEEENLPQRNANPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMSGGWGEGKDLLLQLEDETLKLVEPQNQTLLHAQPIVSIRVWGVGRDSGRERDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMSERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCLDARSQTSTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGSQTP", "length": 711 }, "evidence": [ { "id": "HGNC:581", "url": "https://alliancegenome.org/gene/HGNC:581#orthology", "database": "AGR" }, { "id": "MGI:107765", "url": "https://alliancegenome.org/gene/MGI:107765#orthology", "database": "AGR" }, { "id": "RGD:2122", "url": "https://alliancegenome.org/gene/RGD:2122#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091118-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-127#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9QXJ1-1", "protein_name": "Amyloid beta precursor protein binding family B member 1", "gene_name": "Apbb1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVPSSLSQSAINANSHGGPALSFPLPLHAAHNQLLNAKLQATAVVPKDLRSAMGEGSVPEPGPANAKWLKEGQNQLRRAATAHRDQNRNVTLTLAEEASQEAETAPLGPKGLMHLYSELELSAHNAANRGLHGSALIINTQEQGPDEGEEKAAGEAEEDDEDEEEEEEEEDLSSPPGLPEPLENVEVPSGPQALTDGPREHSKSASLLFGMRNSAASDEDSSWATLSQGSPSYGSPEDTDSFWNPNAFETDSDLPAGWMRVQDTSGTYYWHIPTGTTQWEPPGRASPSQGSSPQEESQLTWTGFAHQEGFEEGEFWKDEPSEEAPMELGLKDPEEATLSFPAQSLSPEPVPQEEEKLSQRNANPGIKCFAVRSLGWVEMTEEELAPGRSSVAVNNCIRQLSYHKNNLHDPMAGGWGEGKDLLLQLEDETLKLVEPQNQTLLHAQPIVSIRVWGVGRDSGSNRDFAYVARDKLTQMLKCHVFRCEAPAKNIATSLHEICSKIMSERRNARCLVNGLSLDHSKLVDVPFQVEFPAPKNELVQKFQVYYLGNVPVAKPVGVDVINGALESVLSSSSREQWTPSHVSVAPATLTILHQQTEAVLGECRVRFLSFLAVGRDVHTFAFIMAAGPASFCCHMFWCEPNAASLSEAVQAACMLRYQKCLDARSQTSTSCLPAPPAESVARRVGWTVRRGVQSLWGSLKPKRLGSQTP", "length": 710 }, "evidence": [ { "id": "HGNC:581", "url": "https://alliancegenome.org/gene/HGNC:581#orthology", "database": "AGR" }, { "id": "MGI:107765", "url": "https://alliancegenome.org/gene/MGI:107765#orthology", "database": "AGR" }, { "id": "RGD:2122", "url": "https://alliancegenome.org/gene/RGD:2122#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091118-127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-127#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7F0N6", "url": "https://www.uniprot.org/uniprotkb/E7F0N6" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "amyloid-beta binding", "id": "GO:0001540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001540", "evidence": [ { "database": "UniProtKB", "id": "E7F0N6", "url": "https://www.uniprot.org/uniprotkb/E7F0N6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 143, "end_pos": 145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 356, "end_pos": 358, "annotation": "n_glycosylation_sequon" }, { "start_pos": 35, "end_pos": 37, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0N6" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 380, "end_pos": 528, "start_aa": "Phe", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7F0N6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0N6" }, { "id": "PS50020", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50020" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WW", "eco_id": "ECO_0000259", "start_pos": 262, "end_pos": 294, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 307 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 143, "end_pos": 145 }, { "start_pos": 356, "end_pos": 358 }, { "start_pos": 35, "end_pos": 37 }, { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1Q587-1", "uniprot_ac": "F1Q587", "uniprot_id": "F1Q587_DANRE", "mass": { "chemical_mass": 62624.0, "monoisotopic_mass": 62624.0 }, "refseq": { "ac": "XP_001922375", "name": "protein FAM124A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922375" }, "gene_names": [ { "name": "fam124a", "type": "recommended", "evidence": [ { "id": "F1Q587", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q587" } ] }, { "name": "fam124a", "type": "synonym", "evidence": [ { "id": "XP_001922375", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922375" } ] } ], "protein_names": [ { "name": "Protein FAM124A isoform X1", "type": "synonym", "evidence": [ { "id": "F1Q587", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q587/entry#names_and_taxonomy" } ] }, { "name": "protein FAM124A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001922375", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922375" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001922375.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001922375", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922375" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q587", "url": "https://www.uniprot.org/uniprotkb/F1Q587" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam124a", "url": "https://www.uniprot.org/uniprotkb/F1Q587", "locus": {} } ], "crossref": [ { "id": "ENSDARG00000075264", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000075264", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "556683", "url": "https://www.ncbi.nlm.nih.gov/gene/556683", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029380", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029380", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556683", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556683", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DVRWQTE", "url": "https://omabrowser.org/oma/group/DVRWQTE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BF08", "url": "https://www.orthodb.org/?gene=A0A8M2BF08", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AW10", "url": "https://www.orthodb.org/?gene=A0A8M3AW10", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1Q587", "url": "https://www.orthodb.org/?gene=F1Q587", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14715", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14715", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14715:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14715:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15067", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15067", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001922375", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922375", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BF08", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BF08", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BF08-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BF08-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AW10", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AW10", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AW10-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AW10-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U1W4", "url": "https://www.uniprot.org/uniprotkb/A0AB32U1W4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U1W4-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32U1W4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q587", "url": "https://www.uniprot.org/uniprotkb/F1Q587", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q587-1", "url": "https://www.uniprot.org/uniprotkb/F1Q587-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MENSVEDECADSGAETGGSDYSLMSSASSDLSMGDQQDPFLVSIHIITDPGQAKTLQQAADQVLSWLHPDLTLFRVSERAGGFSRKHKIRLQHVNELPSLQPALAIILFLQDEYGGEESLERLHSQLRCPPWRYHHTERVNGRGLLPLSAASQDFVTLAPGTPLWALRQVHYGKEIARFTVYCHYETYTEQVRLYRLLLRRKLAQKKEDFSFCVVYSNPETEIQLSFKRMPRGQSPAPTENAVMEIRVRDVGELVPLLPRPCTPISDVRWQTSDYDGNKILLQVQGSRCFRKHTIAKFYHLPSDDPSVTCPPPPEPPPPPPPYGRGPASYRNRRYHRNSSRLRSQTLPSPGSHSSRMAPPVLCEQDVHMERLQKDVELLRAGWASHRTQSLFSLHTDESRSSCASPLGFRPRCFSSMAAPLFRVNVDTLVGAEETDVDTGQTISGSSVDLSVVSGYTQPKLRPHLKAPAPRPKSAPPTDTGPDFADLMYNNSCYMRQTPAPPRAQSISTKFTPCVLNKPKPNSVCVSQPDRGQHKSNGFTPMDECSQEGTVEDEQEFYI", "length": 559, "header": "tr|F1Q587-1|F1Q587_DANRE Isoform 1 of Protein FAM124A isoform X1 OS=Danio rerio OX=7955 GN=fam124a PE=3 SV=1 CANONICAL=F1Q587-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BF08-1", "url": "https://www.uniprot.org/uniprotkb/F1Q587/entry#A0A8M2BF08-1", "sequence": { "sequence": "MSSASSDLSMGDQQDPFLVSIHIITDPGQAKTLQQAADQVLSWLHPDLTLFRVSERAGGFSRKHKIRLQHVNELPSLQPALAIILFLQDEYGGEESLERLHSQLRCPPWRYHHTERVNGRGLLPLSAASQDFVTLAPGTPLWALRQVHYGKEIARFTVYCHYETYTEQVRLYRLLLRRKLAQKKEDFSFCVVYSNPETEIQLSFKRMPRGQSPAPTENAVMEIRVRDVGELVPLLPRPCTPISDVRWQTSDYDGNKILLQVQGSRCFRKHTIAKFYHLPSDDPSVTCPPPPEPPPPPPPYGRGPASYRNRRYHRNSSRLRSQTLPSPGSHSSRMAPPVLCEQDVHMERLQKDVELLRAGWASHRTQSLFSLHTDESRSSCASPLGFRPRCFSSMAAPLFRVNVDTLVGAEETDVDTGQTISGSSVDLSVVSGYTQPKLRPHLKAPAPRPKSAPPTDTGPDFADLMYNNSCYMRQTPAPPRAQSISTKFTPCVLNKPKPNSVCVSQPDRGQHKSNGFTPMDECSQEGTVEDEQEFYI", "length": 536, "header": "tr|A0A8M2BF08-1|F1Q587_DANRE Computationally mapped isoform of Protein FAM124A isoform X1 OS=Danio rerio OX=7955 GN=fam124a PE=3 SV=1 CANONICAL=F1Q587-1" }, "locus": {} }, { "isoform_ac": "A0A8M3AW10-1", "url": "https://www.uniprot.org/uniprotkb/F1Q587/entry#A0A8M3AW10-1", "sequence": { "sequence": "MSALIRERRLEGDLSMGDQQDPFLVSIHIITDPGQAKTLQQAADQVLSWLHPDLTLFRVSERAGGFSRKHKIRLQHVNELPSLQPALAIILFLQDEYGGEESLERLHSQLRCPPWRYHHTERVNGRGLLPLSAASQDFVTLAPGTPLWALRQVHYGKEIARFTVYCHYETYTEQVRLYRLLLRRKLAQKKEDFSFCVVYSNPETEIQLSFKRMPRGQSPAPTENAVMEIRVRDVGELVPLLPRPCTPISDVRWQTSDYDGNKILLQVQGSRCFRKHTIAKFYHLPSDDPSVTCPPPPEPPPPPPPYGRGPASYRNRRYHRNSSRLRSQTLPSPGSHSSRMAPPVLCEQDVHMERLQKDVELLRAGWASHRTQSLFSLHTDESRSSCASPLGFRPRCFSSMAAPLFRVNVDTLVGAEETDVDTGQTISGSSVDLSVVSGYTQPKLRPHLKAPAPRPKSAPPTDTGPDFADLMYNNSCYMRQTPAPPRAQSISTKFTPCVLNKPKPNSVCVSQPDRGQHKSNGFTPMDECSQEGTVEDEQEFYI", "length": 542, "header": "tr|A0A8M3AW10-1|F1Q587_DANRE Computationally mapped isoform of Protein FAM124A isoform X1 OS=Danio rerio OX=7955 GN=fam124a PE=3 SV=1 CANONICAL=F1Q587-1" }, "locus": {} }, { "isoform_ac": "A0AB32U1W4-1", "url": "https://www.uniprot.org/uniprotkb/F1Q587/entry#A0AB32U1W4-1", "sequence": { "sequence": "MGDQQDPFLVSIHIITDPGQAKTLQQAADQVLSWLHPDLTLFRVSERAGGFSRKHKIRLQHVNELPSLQPALAIILFLQDEYGGEESLERLHSQLRCPPWRYHHTERVNGRGLLPLSAASQDFVTLAPGTPLWALRQVHYGKEIARFTVYCHYETYTEQVRLYRLLLRRKLAQKKEDFSFCVVYSNPETEIQLSFKRMPRGQSPAPTENAVMEIRVRDVGELVPLLPRPCTPISDVRWQTSDYDGNKILLQVQGSRCFRKHTIAKFYHLPSDDPSVTCPPPPEPPPPPPPYGRGPASYRNRRYHRNSSRLRSQTLPSPGSHSSRMAPPVLCEQDVHMERLQKDVELLRAGWASHRTQSLFSLHTDESRSSCASPLGFRPRCFSSMAAPLFRVNVDTLVGAEETDVDTGQTISGSSVDLSVVSGYTQPKLRPHLKAPAPRPKSAPPTDTGPDFADLMYNNSCYMRQTPAPPRAQSISTKFTPCVLNKPKPNSVCVSQPDRGQHKSNGFTPMDECSQEGTVEDEQEFYI", "length": 527, "header": "tr|A0AB32U1W4-1|F1Q587_DANRE Computationally mapped isoform of Protein FAM124A isoform X1 OS=Danio rerio OX=7955 GN=fam124a PE=3 SV=1 CANONICAL=F1Q587-1" }, "locus": {} }, { "isoform_ac": "F1Q587-1", "url": "https://www.uniprot.org/uniprotkb/F1Q587/entry#F1Q587-1", "sequence": { "sequence": "MENSVEDECADSGAETGGSDYSLMSSASSDLSMGDQQDPFLVSIHIITDPGQAKTLQQAADQVLSWLHPDLTLFRVSERAGGFSRKHKIRLQHVNELPSLQPALAIILFLQDEYGGEESLERLHSQLRCPPWRYHHTERVNGRGLLPLSAASQDFVTLAPGTPLWALRQVHYGKEIARFTVYCHYETYTEQVRLYRLLLRRKLAQKKEDFSFCVVYSNPETEIQLSFKRMPRGQSPAPTENAVMEIRVRDVGELVPLLPRPCTPISDVRWQTSDYDGNKILLQVQGSRCFRKHTIAKFYHLPSDDPSVTCPPPPEPPPPPPPYGRGPASYRNRRYHRNSSRLRSQTLPSPGSHSSRMAPPVLCEQDVHMERLQKDVELLRAGWASHRTQSLFSLHTDESRSSCASPLGFRPRCFSSMAAPLFRVNVDTLVGAEETDVDTGQTISGSSVDLSVVSGYTQPKLRPHLKAPAPRPKSAPPTDTGPDFADLMYNNSCYMRQTPAPPRAQSISTKFTPCVLNKPKPNSVCVSQPDRGQHKSNGFTPMDECSQEGTVEDEQEFYI", "length": 559, "header": "tr|F1Q587-1|F1Q587_DANRE Isoform 1 of Protein FAM124A isoform X1 OS=Danio rerio OX=7955 GN=fam124a PE=3 SV=1 CANONICAL=F1Q587-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:556683", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556683", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JV50-1", "protein_name": "Family with sequence similarity 124 member A", "gene_name": "Fam124a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPKAAGEEEDCVDSGAETGGSDYSHLSSTSSELSVEEAQDPFLVSIHIIADPGESQPLQEAIDKVLAWVHPDLPLFRVSERRTSRRRRKSPKGAQPALAVVLFLQEEYGEEQILQVHRVLQQPPWRHHHTERVHGRFIPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTIYCRHNSYADSLRFYELILRRSPSQRKADFCIFPIFSNLDVDIQFSLKRLPCDQKPVPTDSSVLEFRVKDIGQLVPLLPNPCSPISEGRWQTEDHDGNKILLQAQRAHKKGPKCSRAHHSSEKKPHSAPPAAIDTPNTGQGSSQTALRDSPSKQMAPLPGNKQEYSPQLNTSSPAWSFQRSKSLFCLPSGGTSTTEPQPLLTGSQRHSASEWKPSRLMSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCNTVEASLSSEGCSSRWPAHKSPEKGPLPAASEVSPDTACVSHPLFTKGSPSPAEITTPGLSASGASLLTESSTPPPCHDPKATQGVQDIVLPPTTVGPEADDMEEFYI", "length": 536 }, "evidence": [ { "id": "F1Q587", "url": "https://omabrowser.org/oma/group/F1Q587/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A1D5NXK4-1", "protein_name": "Family with sequence similarity 124 member A", "gene_name": "FAM124A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MQQQQQQQPRGGEEDCGDSGAETGGSEYSRMSSTSSELSVEDIQDPFLVSVHIITDPGESKTLQQAIDKLLAWIHPELQLFRVSERRVSKKHRKPDKAGVSQPALAVILFLQEEYGEEPILQLHETFQRPPWHYHHTERVHGKFLPYMPCSQDFYTLAPETPLWAIRPVHYGKEIIRFTIYCRNENFVDILKFYELILKRPVCQKKADFCVFPIYSNMEIDIQFSLKKLPKGHVPMPTESAVLEFRVKDVGQLVPLLPNPCSPISEGRWQTEDHDGNRILLQQARSWCRKSAKQNKQPYPSVSTDSHFTTLPGFHPQSHQSVPEQPKEMSQNKVHHANGLGHYLGFSQQDLRHSDQEDFTRRSSSASSILWSFQRSKSLFCLPTVSSSSASETAHFSEAFQFLNTESPATRLKTWRCSPRLNIDDLEDAQETDVDTGRKLSFSDLSVVSAYSALNRFCNDLEASLPPQKQTCSTSTKASTSGRPVSTMCGTFDPMDGSLPSLSEWSSSSFMSASLSKQPKQSSRTASCSLDDCGSIFPASPTNDEEFYI", "length": 549 }, "evidence": [ { "id": "F1Q587", "url": "https://omabrowser.org/oma/group/F1Q587/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3Z5V4-1", "protein_name": "Family with sequence similarity 124, member A", "gene_name": "Fam124a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNPKAGGEEEDCVDSGAETGGSDYSHLSSTSSELSVEEAQDPFLVSIHIIADPGESQPLQEAIDKVLAWVHPDLPLFRVSERRTTRRRRKSPKGAQPALAVVLFLQEEYGEEQILQVHRVLQQPPWRHHHTERVHGRFIPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTIYCRHNSYTDSLRFYELILRRSPSQRKADFCIFPIFSNLDVDIQFSLKRLPCDQKPVPTDSSVLEFRVKDIGQLVPLLPNPCSPISEGRWQTEDHDGNKILLQAQRTHKKAPKYSRAHHSSEKKPHSAPPAAVDTPNTGQGSSQTALHDSPSNQIARLPGDKQEYNTQSSTSSPAWSFPRSKSLFCLPSGGPSPTEPQPLPTNSQRHSASEWKPSRLMSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFYNTIEAPLSSERCSSHWPAHKSPKKGPMPAASEVSPDTACVSHPLFTKGSPRPAETTTPALSASDASLLTESSTHTPCHDPKATQGVQGMLLPPTTVGPETDDMEEFYI", "length": 536 }, "evidence": [ { "id": "F1Q587", "url": "https://omabrowser.org/oma/group/F1Q587/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3N0A0-1", "protein_name": "Family with sequence similarity 124 member A", "gene_name": "FAM124A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDPKAGGGEEDDCVDSGAETGGSDYSHVSSTSSEYSTEEVQDPFLVSIHIIADPGESRPLQEAIDKVLAWIHPDLPLFRVSERRACRRRRRVPKAAQPALAVVLFLQEEYGEEPILQLHRTLQRPPWRHHHTERVPGKFLPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTIYCRHDNYADILKFYELILKRSPSQKKADFCIFPIFSNLDMDIQFSLKRLPCDQTPVPTDSSVLEFRVRDIGELVPLLPNPCSPISEGRWQTEDHDGNKILLQAQKGHRKRPKPGRAHQASEQKPCSTSSPRATAQSRTPGCCSQPPLDASHPGLSQAGPSTRHPQEFARRATSPPSLPWSFQRSKSLFCLPTGDPSPASAAEAQLSASIGGRGQRAPERGHGHLLSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCSPEEAPHPPERGSGLWSERRGFREGPLPTAGGETAGASWATLPVFKGPSGSSATAVTAPPALDTSSLTETPPELPSDAPQAQQTGRDVLAPSVPAGCGDNDTEEFYI", "length": 544 }, "evidence": [ { "id": "F1Q587", "url": "https://omabrowser.org/oma/group/F1Q587/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q86V42-1", "protein_name": "Protein FAM124A", "gene_name": "FAM124A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPKAGGGGEEDDCVDSGAETGGSDYSHLSSTSSELSVEEAQDPFLVSIHIIADPGESQPLQEAIDNVLAWIHPDLPLFRVSERRASRRRRKPPKGAQPALAVVLFLQEEYGEEQILQLHRTLQQPPWRHHHTEQVHGRFLPYLPCSQDFFTLAPGTPLWAIRPVHYGKEIVRFTVYCRYDNYADSLRFYQLILRRSPSQKKADFCIFPIFSNLDVDIQFSLKRLPCDQCPVPTDSSVLEFRVRDIGELVPLLPNPCSPISEGRWQTEDHDGNKILLQAQRVHKKFPKPGRVHHASEKKRHSTPLPSTAVPSHTPGSSQQSPLNSPHPGPIRTGLPPGHQQEFAGRANSTPNPPWSFQRSKSLFCLPTGGPSLASSAEPQWFSNTGAPGHRASEWRHGHLLSIDDLEGAQETDVDTGLRLSSSDLSVVSAYSAPSRFCSTVETPLPSERCSSHWAAHKDSREGPLPTVSRVTTEASWASLPFFTKRSSSSSATARAAPPAPSTSTLTDSSPQLPCDTPKVKQTDGDMPPPPGSAGPGDNDMEEFYI", "length": 546 }, "evidence": [ { "id": "F1Q587", "url": "https://omabrowser.org/oma/group/F1Q587/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 338, "end_pos": 340, "annotation": "n_glycosylation_sequon" }, { "start_pos": 490, "end_pos": 492, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1Q587", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q587" }, { "id": "PF15067", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15067" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM124", "eco_id": "ECO_0000259", "start_pos": 42, "end_pos": 283, "start_aa": "Val", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 338, "end_pos": 340 }, { "start_pos": 490, "end_pos": 492 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F9P7-1", "uniprot_ac": "E7F9P7", "uniprot_id": "E7F9P7_DANRE", "mass": { "chemical_mass": 22229.0, "monoisotopic_mass": 22229.0 }, "refseq": { "ac": "XP_001336048", "name": "dysbindin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001336048" }, "gene_names": [ { "name": "si:ch211-253b8.5", "type": "recommended", "evidence": [ { "id": "E7F9P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F9P7" } ] }, { "name": "si:ch211-253b8.5", "type": "synonym", "evidence": [ { "id": "XP_001336048", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001336048" } ] } ], "protein_names": [ { "name": "Dysbindin isoform X1", "type": "synonym", "evidence": [ { "id": "E7F9P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F9P7/entry#names_and_taxonomy" } ] }, { "name": "dysbindin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001336048", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001336048" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001336048", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001336048" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F9P7", "url": "https://www.uniprot.org/uniprotkb/E7F9P7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-253b8.5", "url": "https://www.uniprot.org/uniprotkb/E7F9P7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141212-327", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141212-327", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000074904", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000074904", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "799859", "url": "https://www.ncbi.nlm.nih.gov/gene/799859", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007531", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007531", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:799859", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799859", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CWLQRGS", "url": "https://omabrowser.org/oma/group/CWLQRGS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F9P7", "url": "https://www.orthodb.org/?gene=E7F9P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16294", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16294", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16294:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16294:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04440", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04440", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001336048", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001336048", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32U2J8", "url": "https://www.uniprot.org/uniprotkb/A0AB32U2J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32U2J8-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32U2J8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GRP5", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GRP5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F9P7", "url": "https://www.uniprot.org/uniprotkb/E7F9P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F9P7-1", "url": "https://www.uniprot.org/uniprotkb/E7F9P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-141212-327", "url": "https://zfin.org/ZDB-GENE-141212-327", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSKGTNLHNKRLPSESEHAQRVPDTEPSQQMRLRERQRFFEEVFQHDVDVYLSSAHLQIDYKRPPLGSISSMEVNVDMLEQMDLMDISDQEALDVFFAASGEEGSLTSPLPDFGHADLEENGLQRSDLPLRIPDPREIKSRMLSTSSNSTCDSQPSNEDGSNTPVVQSDDEDVHEEDMLRTVSTANHTATEESVLPL", "length": 198, "header": "tr|E7F9P7-1|E7F9P7_DANRE Isoform 1 of Dysbindin isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-253b8.5 PE=3 SV=1 CANONICAL=E7F9P7-1" }, "isoforms": [ { "isoform_ac": "A0AB32U2J8-1", "url": "https://www.uniprot.org/uniprotkb/E7F9P7/entry#A0AB32U2J8-1", "sequence": { "sequence": "MRLRERQRFFEEVFQHDVDVYLSSAHLQIDYKRPPLGSISSMEVNVDMLEQMDLMDISDQEALDVFFAASGEEGSLTSPLPDFGHADLEENGLQRSDLPLRIPDPREIKSRMLSTSSNSTCDSQPSNEDGSNTPVVQSDDEDVHEEDMLRTVSTANHTATEESVLPL", "length": 167, "header": "tr|A0AB32U2J8-1|E7F9P7_DANRE Computationally mapped isoform of Dysbindin isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-253b8.5 PE=3 SV=1 CANONICAL=E7F9P7-1" }, "locus": {} }, { "isoform_ac": "A0AC58GRP5-1", "url": "https://www.uniprot.org/uniprotkb/E7F9P7/entry#A0AC58GRP5-1", "sequence": { "sequence": "MSSKGTNLHNKRLPSPLGSISSMEVNVDMLEQMDLMDISDQEALDVFFAASGEEGSLTSPLPDFGHADLEENGLQRSDLPLRIPDPREIKSRMLSTSSNSTCDSQPSNEDGSNTPVVQSDDEDVHEEDMLRTVSTANHTATEESVLPL", "length": 148, "header": "tr|A0AC58GRP5-1|A0AC58GRP5_DANRE Computationally mapped isoform of Dysbindin isoform X3 OS=Danio rerio OX=7955 GN=si:ch211-253b8.5 PE=3 SV=1 CANONICAL=E7F9P7-1" }, "locus": {} }, { "isoform_ac": "E7F9P7-1", "url": "https://www.uniprot.org/uniprotkb/E7F9P7/entry#E7F9P7-1", "sequence": { "sequence": "MSSKGTNLHNKRLPSESEHAQRVPDTEPSQQMRLRERQRFFEEVFQHDVDVYLSSAHLQIDYKRPPLGSISSMEVNVDMLEQMDLMDISDQEALDVFFAASGEEGSLTSPLPDFGHADLEENGLQRSDLPLRIPDPREIKSRMLSTSSNSTCDSQPSNEDGSNTPVVQSDDEDVHEEDMLRTVSTANHTATEESVLPL", "length": 198, "header": "tr|E7F9P7-1|E7F9P7_DANRE Isoform 1 of Dysbindin isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-253b8.5 PE=3 SV=1 CANONICAL=E7F9P7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:799859", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799859", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1TTI0-1", "protein_name": "Dysbindin domain containing 2", "gene_name": "DBNDD2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MDPNPRAALERQQLRLRERQKFFEDILQPETEFVFPLSHLHLESHRPPIGSISSMEVNVDTLEQVELIDLGDQDGADVFLPWEDPPPTPQTAGVDDHPEEPGLPLPTPDRTTSRTSSSSSDTSTNPHSPDPSDGGADTPLAQSDEEEDGGDSRAEPGACS", "length": 160 }, "evidence": [ { "id": "E7F9P7", "url": "https://omabrowser.org/oma/group/E7F9P7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7GDB8-1", "protein_name": "Dysbindin domain-containing protein 2 isoform X2", "gene_name": "Dbndd2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQGPGVIAAMHLSHWAAADPRCPIPHLLEKYARADMDPNPRAALERQQLRLRERQKFFEDILQPETEFVFPLSHLHLESQRPPIGSISSMEVNVDTLEQVEFIDLADQDGADVFLPCEDSPPTPQMSGVDNHPEELSLPVPTPDRTTSRTSSLSSDSSNLRSPNPSDGGADTPLAQSDEEDGDDGGAEPGHCS", "length": 193 }, "evidence": [ { "id": "E7F9P7", "url": "https://omabrowser.org/oma/group/E7F9P7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q9BQY9-1", "protein_name": "Dysbindin domain-containing protein 2", "gene_name": "DBNDD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGAGNFLTALEVPVAALAGAASDRRASCERVSPPPPLPHFRLPPLPRSRLPGPVSRPEPGAPLLGCWLQWGAPSPGPLCLLFRLCSCTCFAPLPAGADMDPNPRAALERQQLRLRERQKFFEDILQPETEFVFPLSHLHLESQRPPIGSISSMEVNVDTLEQVELIDLGDPDAADVFLPCEDPPPTPQSSGMDNHLEELSLPVPTSDRTTSRTSSSSSSDSSTNLHSPNPSDDGADTPLAQSDEEEERGDGGAEPGACS", "length": 259 }, "evidence": [ { "id": "E7F9P7", "url": "https://omabrowser.org/oma/group/E7F9P7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CRD4-1", "protein_name": "Dysbindin domain-containing protein 2", "gene_name": "Dbndd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPNPRAALERQQLRLRERQKFFEDILQPETEFVFPLSHLHLESQRPPIGSISSMEVNVDTLEQVEFIDLADQDGADVFLPCEESSPAPQMSGVDDHPEELSLLVPTSDRTTSRTSSLSSDSSNLRSPNPSDGGGDTPLAQSDEEDGDDGGAEPGPCS", "length": 158 }, "evidence": [ { "id": "E7F9P7", "url": "https://omabrowser.org/oma/group/E7F9P7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7F9P7", "url": "https://www.uniprot.org/uniprotkb/E7F9P7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of signal transduction", "id": "GO:0009966", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009966", "evidence": [ { "database": "UniProtKB", "id": "E7F9P7", "url": "https://www.uniprot.org/uniprotkb/E7F9P7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 149, "end_pos": 151 }, { "start_pos": 187, "end_pos": 189 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FDN5-1", "uniprot_ac": "E7FDN5", "uniprot_id": "E7FDN5_DANRE", "mass": { "chemical_mass": 44534.0, "monoisotopic_mass": 44534.0 }, "refseq": { "ac": "XP_005157765", "name": "uncharacterized protein omgb", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157765" }, "gene_names": [ { "name": "omgb", "type": "recommended", "evidence": [ { "id": "E7FDN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FDN5" } ] }, { "name": "omgb", "type": "synonym", "evidence": [ { "id": "XP_005157765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157765" } ] }, { "name": "omg", "type": "synonym", "evidence": [ { "id": "E7FDN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FDN5" } ] } ], "protein_names": [ { "name": "Oligodendrocyte-myelin glycoprotein", "type": "synonym", "evidence": [ { "id": "E7FDN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FDN5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein omgb", "type": "synonym", "evidence": [ { "id": "XP_005157765", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157765" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 8, 2024 this sequence version replaced XP_005157765.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005157765", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157765" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FDN5", "url": "https://www.uniprot.org/uniprotkb/E7FDN5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "omgb", "url": "https://www.uniprot.org/uniprotkb/E7FDN5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110628-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110628-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000089444", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000089444", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101882436", "url": "https://www.ncbi.nlm.nih.gov/gene/101882436", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101882436", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882436", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "dre:137487219", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:137487219", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PICGQSH", "url": "https://omabrowser.org/oma/group/PICGQSH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7FDN5", "url": "https://www.orthodb.org/?gene=E7FDN5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47114", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47114", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47114:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47114:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00560", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00560", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01462", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-193634", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-193634", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005157765", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157765", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB40E5W1", "url": "https://www.uniprot.org/uniprotkb/A0AB40E5W1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB40E5W1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB40E5W1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FDN5", "url": "https://www.uniprot.org/uniprotkb/E7FDN5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FDN5-1", "url": "https://www.uniprot.org/uniprotkb/E7FDN5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110628-1", "url": "https://zfin.org/ZDB-GENE-110628-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKRKAQIAPASMPANLLLLLLFGVRVLAICPPMCTCSRGHRVVDCSARGLAILPESLQHNIHFLNLSYNRIQNLDGLLKHFDHLRTLDISYNHLHHLPVGLPRALWDIRASGNYIRQLEKNDTAYHWNLQNLDLSFNLLERAVLINNTLSNLQSLNLSHNKFWTVPTNMPYNLEMVDLSHNYLLQILPGSLDRLPRLKRFYLHANRFTSLSKDIFNQLDDLQLLTLGDNPWACEDEENINHLLTWMQKTPAKVLGCPCYTRPTCGEVHLATRRTWHSAAFTEQPLGADARHPGHRVPLHAVTSGYLSKSAQLNVALNANAMNTSEAGEQVLILGGGFRTSTPHSLSTQSSTTIRTRSTKKAHPGKAQSTSHQIHKRSFETTIWSLLCTVVILRAL", "length": 395, "header": "tr|E7FDN5-1|E7FDN5_DANRE Isoform 1 of Oligodendrocyte-myelin glycoprotein OS=Danio rerio OX=7955 GN=omgb PE=4 SV=1 CANONICAL=E7FDN5-1" }, "isoforms": [ { "isoform_ac": "A0AB40E5W1-1", "url": "https://www.uniprot.org/uniprotkb/E7FDN5/entry#A0AB40E5W1-1", "sequence": { "sequence": "MAEAKALNMASKTQFLLLLVAVMITSYNAVGGIDTATYEPLNCTTKCITNGTFNCTNNCTANGTFNCTNNCTDNGIAACLANCMVNVTVNCTNNCTANGTITCTVNGLNLIYNCTPGINNMTSSNITINSTTNNGTTNNSTTNNSTTNNSTTNNSTSWTTPSSNHGNSIAPSFSLVGIMGLSGLLLFYATDINDIFTNLHMLVARDKYSYVIIK", "length": 214, "header": "tr|A0AB40E5W1-1|E7FDN5_DANRE Computationally mapped isoform of Oligodendrocyte-myelin glycoprotein OS=Danio rerio OX=7955 GN=omgb PE=4 SV=1 CANONICAL=E7FDN5-1" }, "locus": {} }, { "isoform_ac": "E7FDN5-1", "url": "https://www.uniprot.org/uniprotkb/E7FDN5/entry#E7FDN5-1", "sequence": { "sequence": "MKRKAQIAPASMPANLLLLLLFGVRVLAICPPMCTCSRGHRVVDCSARGLAILPESLQHNIHFLNLSYNRIQNLDGLLKHFDHLRTLDISYNHLHHLPVGLPRALWDIRASGNYIRQLEKNDTAYHWNLQNLDLSFNLLERAVLINNTLSNLQSLNLSHNKFWTVPTNMPYNLEMVDLSHNYLLQILPGSLDRLPRLKRFYLHANRFTSLSKDIFNQLDDLQLLTLGDNPWACEDEENINHLLTWMQKTPAKVLGCPCYTRPTCGEVHLATRRTWHSAAFTEQPLGADARHPGHRVPLHAVTSGYLSKSAQLNVALNANAMNTSEAGEQVLILGGGFRTSTPHSLSTQSSTTIRTRSTKKAHPGKAQSTSHQIHKRSFETTIWSLLCTVVILRAL", "length": 395, "header": "tr|E7FDN5-1|E7FDN5_DANRE Isoform 1 of Oligodendrocyte-myelin glycoprotein OS=Danio rerio OX=7955 GN=omgb PE=4 SV=1 CANONICAL=E7FDN5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101882436", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882436", "resource": "KEGG Pathway" }, { "id": "dre:137487219", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:137487219", "resource": "KEGG Pathway" }, { "id": "R-DRE-193634", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-193634", "resource": "Reactome", "description": "Axonal growth inhibition (RHOA activation)" } ], "orthologs": [ { "uniprot_canonical_ac": "F7EYB9-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "Omg", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALMEYQILKMSSCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLTTLPPGLQENIIHLNLSYNHFTDLHNQLTPYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLLQLQEITLHNNRWSCDHTQNITYLLKWMMETKAHVIGIPCSKQVSSLKEQSMYPTPPGFTSSLFTMSEMQTVDTINSLSMVTQPKVTNIPKQYRGKDTTFGVTLSKDTTFSSTDRALEPYPEDTPTEMTSSREAAAATLTIHLQDGMSSNASLTSAAKSSPAPVTLSITSGMPNNFSEMPQQSTTLNLRREETTANVKTQPPSSASAWKVNASLLLMLNAVVMLAG", "length": 443 }, "evidence": [ { "id": "MGI:106586", "url": "https://alliancegenome.org/gene/MGI:106586#orthology", "database": "AGR" }, { "id": "HGNC:8135", "url": "https://alliancegenome.org/gene/HGNC:8135#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P23515-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "OMG", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEYQILKMSLCLFILLFLTPGILCICPLQCICTERHRHVDCSGRNLSTLPSGLQENIIHLNLSYNHFTDLHNQLTQYTNLRTLDISNNRLESLPAHLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQNITYLLKWMMETKAHVIGTPCSTQISSLKEHNMYPTPSGFTSSLFTVSGMQTVDTINSLSVVTQPKVTKIPKQYRTKETTFGATLSKDTTFTSTDKAFVPYPEDTSTETINSHEAAAATLTIHLQDGMVTNTSLTSSTKSSPTPMTLSITSGMPNNFSEMPQQSTTLNLWREETTTNVKTPLPSVANAWKVNASFLLLLNVVVMLAV", "length": 440 }, "evidence": [ { "id": "MGI:106586", "url": "https://alliancegenome.org/gene/MGI:106586#orthology", "database": "AGR" }, { "id": "HGNC:8135", "url": "https://alliancegenome.org/gene/HGNC:8135#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110628-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110628-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q63912-1", "protein_name": "Oligodendrocyte-myelin glycoprotein", "gene_name": "Omg", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEYQILKMSSCLFILLFLTPGILCICPLQCTCTERHRHVDCSGRNLTTLPPGLQENIIHLNLSYNHFTDLHNQLTPYTNLRTLDISNNRLESLPAQLPRSLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLEKVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDLSNNSLTQILPGTLINLTNLTHLYLHNNKFTFIPEQSFDQLLQLQEITLHNNRWSCDHKQNITYLLKWVMETKAHVIGTPCSKQVSSLKEQSMYPTPPGFTSSLFTMSEMQTVDTINSLSMVTQPKVTKTPKQYRGKETTFGVTLSKDTTFSSTDRAVVAYPEDTPTEMTNSHEAAAATLTIHLQDGMSSNASLTSATKSPPSPVTLSIARGMPNNFSEMPRQSTTLNLRREETTANGNTRPPSAASAWKVNASLLLMLNAVVMLAG", "length": 440 }, "evidence": [ { "id": "MGI:106586", "url": "https://alliancegenome.org/gene/MGI:106586#orthology", "database": "AGR" }, { "id": "HGNC:8135", "url": "https://alliancegenome.org/gene/HGNC:8135#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110628-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110628-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "neuron projection regeneration", "id": "GO:0031102", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031102", "evidence": [ { "database": "UniProtKB", "id": "E7FDN5", "url": "https://www.uniprot.org/uniprotkb/E7FDN5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 146, "end_pos": 148, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" }, { "start_pos": 322, "end_pos": 324, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FDN5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FDN5" }, { "id": "PF01462", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01462" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 29, "end_pos": 50, "start_aa": "Ile", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 146, "end_pos": 148 }, { "start_pos": 156, "end_pos": 158 }, { "start_pos": 322, "end_pos": 324 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F1Y9-1", "uniprot_ac": "E7F1Y9", "uniprot_id": "E7F1Y9_DANRE", "mass": { "chemical_mass": 49849.0, "monoisotopic_mass": 49849.0 }, "refseq": { "ac": "XP_002665637", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665637" }, "gene_names": [ { "name": "LOC100330546", "type": "recommended", "evidence": [ { "id": "E7F1Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9" } ] }, { "name": "LOC100500933", "type": "recommended", "evidence": [ { "id": "E7F1Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9" } ] }, { "name": "LOC796282", "type": "recommended", "evidence": [ { "id": "E7F1Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9" } ] }, { "name": "nkd3", "type": "recommended", "evidence": [ { "id": "E7F1Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9" } ] }, { "name": "LOC100330546", "type": "synonym", "evidence": [ { "id": "XP_002665637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665637" } ] }, { "name": "si:dkey-231l1.4", "type": "synonym", "evidence": [ { "id": "E7F1Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9" } ] } ], "protein_names": [ { "name": "Uncharacterized protein", "type": "synonym", "evidence": [ { "id": "E7F1Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_002665637", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665637" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_002665637", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665637" } ] }, { "annotation": "Cell autonomous antagonist of the canonical Wnt signaling pathway.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M9PAS4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAS4#function" }, { "database": "UniProtKB", "id": "RU367060", "url": "https://www.uniprot.org/uniprotkb/RU367060#function" }, { "database": "UniProtKB", "id": "I3ITM9", "url": "https://www.uniprot.org/uniprotkb/I3ITM9#function" }, { "database": "UniProtKB", "id": "A0AC58HX58", "url": "https://www.uniprot.org/uniprotkb/A0AC58HX58#function" }, { "database": "UniProtKB", "id": "A0AC58HX59", "url": "https://www.uniprot.org/uniprotkb/A0AC58HX59#function" }, { "database": "UniProtKB", "id": "A0AC58HX84", "url": "https://www.uniprot.org/uniprotkb/A0AC58HX84#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F1Y9", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC100330546", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060503-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060503-63", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000013174", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000013174", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSDARG00000069984", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000069984", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSDARG00000096278", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000096278", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100330546", "url": "https://www.ncbi.nlm.nih.gov/gene/100330546", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "100500933", "url": "https://www.ncbi.nlm.nih.gov/gene/100500933", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "566577", "url": "https://www.ncbi.nlm.nih.gov/gene/566577", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "796282", "url": "https://www.ncbi.nlm.nih.gov/gene/796282", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040140", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040140", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100330546", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330546", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "dre:100500933", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100500933", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "dre:566577", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566577", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "dre:796282", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796282", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CQRELEC", "url": "https://omabrowser.org/oma/group/CQRELEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "FERFAHF", "url": "https://omabrowser.org/oma/group/FERFAHF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PRQMIAW", "url": "https://omabrowser.org/oma/group/PRQMIAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EZ18", "url": "https://www.orthodb.org/?gene=E7EZ18", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F1Y9", "url": "https://www.orthodb.org/?gene=E7F1Y9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "I3ITM9", "url": "https://www.orthodb.org/?gene=I3ITM9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22611", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22611", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22611:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22611:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_002665637", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665637", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M1NE98", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NE98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1NE98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NE98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PAS4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAS4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PAS4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PAS4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TDG5", "url": "https://www.uniprot.org/uniprotkb/A0AB32TDG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TDG5-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TDG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HX58", "url": "https://www.uniprot.org/uniprotkb/A0AC58HX58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HX58-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HX58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HX59", "url": "https://www.uniprot.org/uniprotkb/A0AC58HX59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HX59-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HX59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HX84", "url": "https://www.uniprot.org/uniprotkb/A0AC58HX84", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HX84-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HX84-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZ18", "url": "https://www.uniprot.org/uniprotkb/E7EZ18", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZ18-1", "url": "https://www.uniprot.org/uniprotkb/E7EZ18-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F1Y9", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F1Y9-1", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3ITM9", "url": "https://www.uniprot.org/uniprotkb/I3ITM9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "I3ITM9-1", "url": "https://www.uniprot.org/uniprotkb/I3ITM9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060503-63", "url": "https://zfin.org/ZDB-GENE-060503-63", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSLFTSVFRQLSACFTPSWGRRLSPQIADIGAEAGESKAMSTQKHRKVKSHHGHRPGKEGEGLKDQAEEEKQALSAENIQSTEREGGNGEPGGKKRKRRKLKNKKTLPLPVEVKPLPAPACFSSSSPPVGDQPEHPDVLALPAAGLKPLLKDKESLPRLVEVKPLPASACFSSLTPVGDQPEHPEVLVLPASHLKALSPLSNPASRPQSPVEETDEVLPSSVIQVAPCVSPEPVLLPLQSSSEVASLCSIPSFSEPSLLQSPPETLPIPPIFAFDKVVSLVKPQASECSPSSGLMLFDFEDEELEFMEYTEEDIEAFYESEMKPRRMAAWLEQEEVTEVQIDGGKGASQVIQNPLNEVSRDEAFEELLIQAFCTGPPVYTEIKSRKKPKRNGPLVLFSLMEEKVKKKQEKKLRKEEERNERNLLRERYRNDPKLKHLCINKHNPNFCWS", "length": 449, "header": "tr|E7F1Y9-1|E7F1Y9_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100330546 PE=4 SV=1 CANONICAL=E7F1Y9-1" }, "isoforms": [ { "isoform_ac": "A0A8M1NE98-1", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9/entry#A0A8M1NE98-1", "sequence": { "sequence": "MSLFTSVFRQLSACFTPSWGRRLSPQIADIGAEAGESKAMSTQKHRKVKSHHGHRPGKEGEGLKDQAEEEKQALSAENIQSTEREGGNGEPGGKKRKRRKLKNKKTLPLPVEVKPLPAPACFSSSPPVGDQPEHPDVLALPAAGLKPLLKDKESLPRLVEVKPLPASACFSSLTPVGDQPEHPEVLVLPASHLKALSPLSNPASRPQSPVEETDEVLPSSVIQVAPCVSPEPVLLPLQSSSEVASLCSIPSFSEPSLLQSPPETLPIPPIFAFTEVVSLVKPQASECSPSSGLMLFDFEDEELKFMEYTEEDIEAFYESEMKPRRMAAWLEQEEVTEVQKDGGKGASQVIQNPLNEVSRDEAFEELLIQAFCTGPPVYTEIKSRKKPKRNGPLVLFSLMEEKVKKKQEKKLRKEEERNERNLLRERYRNDPKLKHLCINKHNPNFCWS", "length": 448, "header": "tr|A0A8M1NE98-1|E7F1Y9_DANRE Computationally mapped isoform of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100330546 PE=4 SV=1 CANONICAL=E7F1Y9-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PAS4-1", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9/entry#A0A8M9PAS4-1", "sequence": { "sequence": "MGKLQSKHAYKRRENPEGDAFKEVACSEELDRNKQDLCVREAEEDHLSDHYCSLQVTLPPQRLLETSESLHSCPENGRQHPQKDTVRRSGKTDNKLSLMQTICELVEASVKQLVLSNGTTLRVKLSVTPLTSRKTYRKDAGISLNERDQMNETGCSKESQHPQIRVLNSDQLSAPERKQYSVDENTERRNHYLDLAGIENYTSRFEETSAKDPPQDVPSSRVHHRRSQPETCIRVDSSGKSLPFLRSLCSRSKSVGYTAATSKPSKHHGHHPITWCYPSQQQQQHPLLHSSSKRMRARARETASPSRNPQDRDLNCGTALQPTGLIPVPQRHEHHHHHEHHHHHHHHHYHPA", "length": 352, "header": "tr|A0A8M9PAS4-1|E7F1Y9_DANRE Computationally mapped isoform of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100330546 PE=4 SV=1 CANONICAL=E7F1Y9-1" }, "locus": {} }, { "isoform_ac": "A0AB32TDG5-1", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9/entry#A0AB32TDG5-1", "sequence": { "sequence": "MSLFTSVFRQLSACFTPSWGRRLSPQIADIGAEAGESKAMSTQKHRKVKSHHGHRPDKEGEGLKDQAEEEKQALSAENIQSTEREAGGNGEPGGKKRKRRKLKNKKTLPLPVEVKPLPAPACFSSSPPVGDQPEHPDVLALPAAGLKPLLKDKESLPRLVEVKPLPASACFSSLTPVGDQPEHPEVLVLPASRLKALSPLSNPASRPQSPVEETDEVLPSSVIQVAPCVSPEPVLLPLQSSSEVASLCSIPSFSEPSLLQSPPETLPIPPIFAFDEVVSLVKPQASECSPSSGLMLFDFEDEELEFMEYTEEDIEAFYESEMKPRRMAAWLEQEEVTEVQKDGGKGASQVIQNPLNEVSRDEAFEELLIQAFCTGPPVYTEIKSRKKPKRNGPLVLFSLMEEKVKKKQEKKLRKEEERNERNLLRERYRNDPKLKHLCINKHNPNFCWS", "length": 449, "header": "tr|A0AB32TDG5-1|E7F1Y9_DANRE Computationally mapped isoform of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100330546 PE=4 SV=1 CANONICAL=E7F1Y9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HX58-1", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9/entry#A0AC58HX58-1", "sequence": { "sequence": "MITLYGLDNSGKITKENKLSLMQTICELVEASVKQLVLSNGTTLRVKLSVTPLTSRKTYRKDAGISLNERDQMNETGCSKESQHPQIRVLNSDQLSAPERKQYSVDENTERRNHYLDLAGIENYTSRFEETSAKDPPQDVPSSRVHHRRSQPETCIRVDSSGKSLPFLRSLCSRSKSVGYTAATSKPSKHHGHHPITWCYPSQQQQQHPLLHSSSKRMRARARETASPSRNPQDRDLNCGTALQPTGLIPVPQRHEHHHHHEHHHHHHHHHYHPA", "length": 275, "header": "tr|A0AC58HX58-1|A0AC58HX58_DANRE Computationally mapped isoform of Protein naked cuticle homolog OS=Danio rerio OX=7955 GN=LOC100500933 PE=3 SV=1 CANONICAL=E7F1Y9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HX59-1", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9/entry#A0AC58HX59-1", "sequence": { "sequence": "MGKLQSKHAYKRRENPEGDAFKEVACSEELDRNKQDLCVREAEEDHLSDHYCSLQVTLPPQRLLETSESLHSCPENGRQHPQKDTVRRSGKTDSTYKLHTEMPTDPAEAQTSNLLPEKECNVSIPDENRQEWMITLYGLDNSGKITKENKLSLMQTICELVEASVKQLVLSNGTTLRVKLSVTPLTSRKTYRKDAGISLNERDQMNETGCSKESQHPQIRVLNSDQLSAPERKQYSVDENTERRNHYLDLAGIENYTSRFEETSAKDPPQDVPSSRVHHRRSQPETCIRVDSSGKSLPFLRSLCSRSKSVGYTAATSKPSKHHGHHPITWCYPSQQQQQHPLLHSSSKRMRARARETASPSRNPQDRDLNCGTALQPTGLIPVPQRHEHHHHHEHHHHHHHHHYHPA", "length": 407, "header": "tr|A0AC58HX59-1|A0AC58HX59_DANRE Computationally mapped isoform of Protein naked cuticle homolog OS=Danio rerio OX=7955 GN=LOC100500933 PE=3 SV=1 CANONICAL=E7F1Y9-1" }, "locus": {} }, { "isoform_ac": "A0AC58HX84-1", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9/entry#A0AC58HX84-1", "sequence": { "sequence": "MGKLQSKHAYKRRENPEGDAFKEVACSEELDRNKQDLCVREAEEDHLSDHYCSLQVTLPPQRLLETSESLHSCPENGRQHPQKDTVRRSGKTDEKECNVSITDENQQEWMITLYDLDIFGIAAPAFSVTWSIRNHSNMINSFIHFLVGLVPLLIWGRHSGMNHQLIQHTFYRAHTNSTQKCQLTQPRLKPATFFL", "length": 195, "header": "tr|A0AC58HX84-1|A0AC58HX84_DANRE Computationally mapped isoform of Protein naked cuticle homolog OS=Danio rerio OX=7955 GN=LOC100500933 PE=3 SV=1 CANONICAL=E7F1Y9-1" }, "locus": {} }, { "isoform_ac": "E7EZ18-1", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9/entry#E7EZ18-1", "sequence": { "sequence": "MSLFTSVFRQLSACFTPSWGRRLSPQIADIGAEAGESKAMSTQKHRKVKSHHGHRPDKEGEGLKDQAEEEKQALSAENIQSTEREGGNGEPGGKKRKRRKLKNKKTLPLPVEVKPLPAPACFSSSPPVGDQPEHPDVLALPAAGLKPLLKDKESLPRLVEVKPLPASACFSSLTPVGDQPEHPEVLVLPASRLKALSPLSNPASRPQSPVEETDEVLPSSVIQVAPCVSPEPVLLPLQSSSEVASLCSIPSFSEPSLLQSPPETLPIPPIFAFDEVVSLVKPQASECSPSSGLMLFDFEDEELEFMEYTEEDIEAFYESEMKPRRMAAWLEQEEVTEVQKDGGKGASQVIQNPLNEVSRDEAFEELLIQAFCTGPPVYTEIKSRKKPKRNGPLVLFSLMEEKVKKKQEKKLRKEEERNERNLLRERYRNDPKLKHLCINKHNPNFCWS", "length": 448, "header": "tr|E7EZ18-1|E7EZ18_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=LOC796282 PE=4 SV=1 CANONICAL=E7F1Y9-1" }, "locus": {} }, { "isoform_ac": "E7F1Y9-1", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9/entry#E7F1Y9-1", "sequence": { "sequence": "MSLFTSVFRQLSACFTPSWGRRLSPQIADIGAEAGESKAMSTQKHRKVKSHHGHRPGKEGEGLKDQAEEEKQALSAENIQSTEREGGNGEPGGKKRKRRKLKNKKTLPLPVEVKPLPAPACFSSSSPPVGDQPEHPDVLALPAAGLKPLLKDKESLPRLVEVKPLPASACFSSLTPVGDQPEHPEVLVLPASHLKALSPLSNPASRPQSPVEETDEVLPSSVIQVAPCVSPEPVLLPLQSSSEVASLCSIPSFSEPSLLQSPPETLPIPPIFAFDKVVSLVKPQASECSPSSGLMLFDFEDEELEFMEYTEEDIEAFYESEMKPRRMAAWLEQEEVTEVQIDGGKGASQVIQNPLNEVSRDEAFEELLIQAFCTGPPVYTEIKSRKKPKRNGPLVLFSLMEEKVKKKQEKKLRKEEERNERNLLRERYRNDPKLKHLCINKHNPNFCWS", "length": 449, "header": "tr|E7F1Y9-1|E7F1Y9_DANRE Isoform 1 of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100330546 PE=4 SV=1 CANONICAL=E7F1Y9-1" }, "locus": {} }, { "isoform_ac": "I3ITM9-1", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9/entry#I3ITM9-1", "sequence": { "sequence": "MGKLQSKHAYKRRENPEGDAFKEVACSEELDRNKQDLCVREAEEDHLSDHYCSLQVTLPPQRLLETSESLHSCPENGRQHPQKDTVRRSGKTDEKECNVSIPDENRQEWMITLYGLDNSGKITKENKLSLMQTICELVEASVKQLVLSNGTTLRVKLSVTPLTSRKTYRKDAGISLNERDQMNETGCSKESQHPQIRVLNSDQLSAPERKQYSVDENTERRNHYLDLAGIENYTSRFEETSAKDPPQDVPSSRVHHRRSQPETCIRVDSSGKSLPFLRSLCSRSKSVGYTAATSKPSKHHGHHPITWCYPSQQQQQHPLLHSSSKRMRARARETASPSRNPQDRDLNCGTALQPTGLIPVPQRHEHHHHHEHHHHHHHHHYHPA", "length": 384, "header": "tr|I3ITM9-1|E7F1Y9_DANRE Computationally mapped isoform of Uncharacterized protein OS=Danio rerio OX=7955 GN=LOC100330546 PE=4 SV=1 CANONICAL=E7F1Y9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Zebrafish Nkd1 promotes Dvl degradation and is required for left-right patterning.", "journal": "Dev. Biol.", "date": "2010", "authors": "Schneider Igor, Schneider Patricia N, Derry Sarah W, Lin Shengda, Barton Lacy J, Westfall Trudi, Slusarski Diane C", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1NE98", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NE98" } ], "reference": [ { "type": "PubMed", "id": "20858476", "url": "https://glygen.org/publication/PubMed/20858476" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "I3ITM9", "url": "https://www.uniprot.org/uniprotkb/I3ITM9" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "The Nkd EF-hand domain modulates divergent wnt signaling outputs in zebrafish.", "journal": "Dev. Biol.", "date": "2018", "authors": "Marsden Autumn N, Derry Sarah W, Schneider Igor, Scott C Anthony, Westfall Trudi A, Brastrom Lindy K, Shea Madeline A, Dawson Deborah V, Slusarski Diane C", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1NE98", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NE98" } ], "reference": [ { "type": "PubMed", "id": "29180104", "url": "https://glygen.org/publication/PubMed/29180104" } ] }, { "title": "Transcriptomic analysis of zebrafish (Danio rerio) embryos to assess integrated biotoxicity of Xitiaoxi River waters.", "journal": "Environ. Pollut.", "date": "2018", "authors": "Zhou Shengli, Wei Zheng, Chu Tianyi, Yu Haiyan, Li Shuying, Zhang Wei, Gui Wenjun", "evidence": [ { "database": "UniProtKB", "id": "A0A8M1NE98", "url": "https://www.uniprot.org/uniprotkb/A0A8M1NE98" } ], "reference": [ { "type": "PubMed", "id": "29958174", "url": "https://glygen.org/publication/PubMed/29958174" } ] } ], "pathway": [ { "id": "dre:100330546", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330546", "resource": "KEGG Pathway" }, { "id": "dre:100500933", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100500933", "resource": "KEGG Pathway" }, { "id": "dre:566577", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566577", "resource": "KEGG Pathway" }, { "id": "dre:796282", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796282", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7F1Y9", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7F1Y9", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E7F1Y9", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "negative regulation of canonical Wnt signaling pathway", "id": "GO:0090090", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0090090", "evidence": [ { "database": "UniProtKB", "id": "E7F1Y9", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9" } ], "pmid": "" }, { "name": "Wnt signaling pathway", "id": "GO:0016055", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016055", "evidence": [ { "database": "UniProtKB", "id": "E7F1Y9", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9" } ], "pmid": "" }, { "name": "Kupffer's vesicle development", "id": "GO:0070121", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070121", "evidence": [ { "database": "UniProtKB", "id": "E7F1Y9", "url": "https://www.uniprot.org/uniprotkb/E7F1Y9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F5M2-1", "uniprot_ac": "E7F5M2", "uniprot_id": "E7F5M2_DANRE", "mass": { "chemical_mass": 76625.0, "monoisotopic_mass": 76625.0 }, "refseq": { "ac": "NP_001430165", "name": "transmembrane protein 260 isoform 1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430165" }, "gene_names": [ { "name": "tmem260", "type": "recommended", "evidence": [ { "id": "E7F5M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5M2" } ] }, { "name": "fc80c01", "type": "synonym", "evidence": [ { "id": "NP_001430165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430165" } ] }, { "name": "tmem260", "type": "synonym", "evidence": [ { "id": "NP_001430165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430165" } ] }, { "name": "wu:fc80c01", "type": "synonym", "evidence": [ { "id": "NP_001430165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430165" } ] } ], "protein_names": [ { "name": "Protein O-mannosyl-transferase TMEM260 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F5M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5M2/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 260 isoform 1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001430165", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430165" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01023210.1, SRR26395013.1243910.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476731, SAMEA4476745 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000017.1. On Sep 9, 2025 this sequence version replaced XP_688103.5.", "evidence": [ { "database": "RefSeq", "id": "NP_001430165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430165" } ] } ], "disease": [ { "disease_id": "DOID:0060060", "recommended_name": { "id": "DOID:0060060", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060060", "name": "non-Hodgkin lymphoma", "description": "A lymphoma that is characterized as any kind of lymphoma except Hodgkin's lymphoma." }, "synonyms": [ { "id": "MONDO:0011508", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011508", "name": "lymphoma, non-Hodgkin, familial", "description": "" }, { "id": "MONDO:0011508", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011508", "name": "lymphoma, follicular, somatic", "description": "" }, { "id": "MONDO:0011508", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011508", "name": "lymphoma, non-Hodgkin", "description": "" }, { "id": "MONDO:0011508", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011508", "name": "lymphoma, non-Hodgkin, familial", "description": "" }, { "id": "MONDO:0011508", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011508", "name": "lymphoma, non-Hodgkin, somatic", "description": "" }, { "id": "MIM:605027", "resource": "MIM", "url": "https://www.omim.org/entry/605027", "name": "Familial non-Hodgkin lymphoma", "description": "Familial non-Hodgkin lymphoma" } ], "unlinked_id_list": [ "DOID:0081452", "DOID:6536", "DOID:706", "DOID:0050743" ], "evidence": [ { "id": "0060060", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060060" } ] }, { "disease_id": "DOID:0081312", "recommended_name": { "id": "DOID:0081312", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0081312", "name": "T-cell non-Hodgkin lymphoma", "description": "A non-Hodgkin lymphoma of T-cell lineage." }, "synonyms": [], "unlinked_id_list": [ "DOID:0050743" ], "evidence": [ { "id": "0081312", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0081312" } ] }, { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "GC", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F5M2", "url": "https://www.uniprot.org/uniprotkb/E7F5M2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmem260", "url": "https://www.uniprot.org/uniprotkb/E7F5M2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-4198", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4198", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000076362", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000076362", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "559650", "url": "https://www.ncbi.nlm.nih.gov/gene/559650", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR021280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:559650", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559650", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HSVNLMC", "url": "https://omabrowser.org/oma/group/HSVNLMC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F5M2", "url": "https://www.orthodb.org/?gene=E7F5M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16214", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16214", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16214:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16214:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11028", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11028", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001430165", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001430165", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLK5", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLK5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLK5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLK5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T4B4", "url": "https://www.uniprot.org/uniprotkb/A0AB32T4B4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T4B4-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T4B4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPF1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPF1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HPF1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HPF1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F5M2", "url": "https://www.uniprot.org/uniprotkb/E7F5M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F5M2-1", "url": "https://www.uniprot.org/uniprotkb/E7F5M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-4198", "url": "https://zfin.org/ZDB-GENE-030131-4198", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSDRWTWSLTGATVAGVSALYVGCAPRAVPGGDSGELITAACELGVAHPPGYPLFTMMSSLMLSLLPLSSPAHSINVLCAVFGAGASGALCFTVCRVAEPGPGAVLAGGVFAVSRLVWQWSVVAEVFSLNNLFVGVLFSLSACFHCADTVQQKKKFALWGALFCGLSLCNQHTLVLYVVVIIPWALLHLYTHNGLSFFDLVSLGTCFLAGFVPYMYLPVSSYLNRARWSWGDQTSVHGLLTHLLRAEYGTFSLAKTNESLNLLEMLRAQWNHCVNDLTVPVLALALLGMLLSLRSRLRCIFVCLIVTMVSIYSVFFAWRANLNIEKPLLLGVVERFWLQADAGVCVLAGLGLSWLVCCLTGHLGKGTVWNTGAWILTAGLISHMISLNHRDCDQSSNDVVDRFSREVVLSLPQGSLVLTRGDLPGNTLRYQHYCQSLRPDLSLVDQEMMTYNWYVAKLQRHLPGVTFPGHRWDPVNAVEKKTFSIEQFLKRNLHRPVFVCIGLTEGDPSWEGSFSRWPWGVCEQLLPVKTPFDPKKWAQKTHNLYNWSEPHDSFHPGSWERVANEEMWQARMKTAFFLFDLAENAEKEQQGRLYEISYKLYCQIVDSQVDYPANWDKNLALAAERLLQSGGRGYGLDSLMSRSIRHFSRYLKREPSDPQSKAIRSIITHLRKEREKFRDRQKA", "length": 684, "header": "tr|E7F5M2-1|E7F5M2_DANRE Isoform 1 of Protein O-mannosyl-transferase TMEM260 isoform X1 OS=Danio rerio OX=7955 GN=tmem260 PE=4 SV=1 CANONICAL=E7F5M2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLK5-1", "url": "https://www.uniprot.org/uniprotkb/E7F5M2/entry#A0A8M9PLK5-1", "sequence": { "sequence": "MSSDRWTWSLTGATVAGVSALYVGCAPRAVPGGDSGELITAACELGVAHPPGYPLFTMMSSLMLSLLPLSSPAHSINVLCAVFGAGASGALCFTVCRVAEPGPGAVLAGGVFAVSRLVWQWSVVAEVFSLNNLFVGVLFSLSACFHCADTVQQKKKFALWGALFCGLSLCNQHTLVLYVVVIIPWALLHLYTHNGLSFFDLVSLGTCFLAGFVPYMYLPVSSYLNRARWSWGDQTSVHGLLTHLLRAEYGTFSLAKTNESLNLLEMLRAQWNHCVNDLTVPVLALALLGMLLSLRSRLRCIFVCLIVTMVSIYSVFFAWRANLNIEKPLLLGVVERFWLQADAGVCVLAGLGLSWLVCCLTGHLGKGTVWNTGAWILTAGLISHMISLNHRDCDQSSNDVVDRFSREVVLSLPQGSLVLTRGDLPGNTLRYQHYCQSLRPDLSLVDQEMMTYNWYVAKLQRHLPGVTFPGHRWDPVNAVEKKTFSIEQFLKRNLQPVFVCIGLTEGDPSWEGSFSRWPWGVCEQLLPVKTPFDPKKWAQKTHNLYNWSEPHDSFHPGSWERVANEEMWQARMKTAFFLFDLAENAEKEQQGRLYEISYKLYCQIVDSQVDYPANWDKNLALAAERLLQSGGRGYGLDSLMSRSIRHFSRYLKREPSDPQSKAIRSIITHLRKEREKFRDRQKA", "length": 683, "header": "tr|A0A8M9PLK5-1|E7F5M2_DANRE Computationally mapped isoform of Protein O-mannosyl-transferase TMEM260 isoform X1 OS=Danio rerio OX=7955 GN=tmem260 PE=4 SV=1 CANONICAL=E7F5M2-1" }, "locus": {} }, { "isoform_ac": "A0AB32T4B4-1", "url": "https://www.uniprot.org/uniprotkb/E7F5M2/entry#A0AB32T4B4-1", "sequence": { "sequence": "MSVVLRALCPVETQVAHPPGYPLFTMMSSLMLSLLPLSSPAHSINVLCAVFGAGASGALCFTVCRVAEPGPGAVLAGGVFAVSRLVWQWSVVAEVFSLNNLFVGVLFSLSACFHCADTVQQKKKFALWGALFCGLSLCNQHTLVLYVVVIIPWALLHLYTHNGLSFFDLVSLGTCFLAGFVPYMYLPVSSYLNRARWSWGDQTSVHGLLTHLLRAEYGTFSLAKTNESLNLLEMLRAQWNHCVNDLTVPVLALALLGMLLSLRSRLRCIFVCLIVTMVSIYSVFFAWRANLNIEKPLLLGVVERFWLQADAGVCVLAGLGLSWLVCCLTGHLGKGTVWNTGAWILTAGLISHMISLNHRDCDQSSNDVVDRFSREVVLSLPQGSLVLTRGDLPGNTLRYQHYCQSLRPDLSLVDQEMMTYNWYVAKLQRHLPGVTFPGHRWDPVNAVEKKTFSIEQFLKRNLHRPVFVCIGLTEGDPSWEGSFSRWPWGVCEQLLPVKTPFDPKKWAQKTHNLYNWSEPHDSFHPGSWERVANEEMWQARMKTAFFLFDLAENAEKEQQGRLYEISYKLYCQIVDSQVDYPANWDKNLALAAERLLQSGGRGYGLDSLMSRSIRHFSRYLKREPSDPQSKAIRSIITHLRKEREKFRDRQKA", "length": 652, "header": "tr|A0AB32T4B4-1|E7F5M2_DANRE Computationally mapped isoform of Protein O-mannosyl-transferase TMEM260 isoform X1 OS=Danio rerio OX=7955 GN=tmem260 PE=4 SV=1 CANONICAL=E7F5M2-1" }, "locus": {} }, { "isoform_ac": "A0AC58HPF1-1", "url": "https://www.uniprot.org/uniprotkb/E7F5M2/entry#A0AC58HPF1-1", "sequence": { "sequence": "MSVVLRALCPVETQVAHPPGYPLFTMMSSLMLSLLPLSSPAHSINVLCAVFGAGASGALCFTVCRVAEPGPGAVLAGGVFAVSRLVWQWSVVAEVFSLNNLFVGVLFSLSACFHCADTVQQKKKFALWGALFCGLSLCNQHTLVLYVVVIIPWALLHLYTHNGLSFFDLVSLGTCFLAGFVPYMYLPVSSYLNRARWSWGDQTSVHGLLTHLLRAEYGTFSLAKTNESLNLLEMLRAQWNHCVNDLTVPVLALALLGMLLSLRSRLRCIFVCLIVTMVSIYSVFFAWRANLNIEKPLLLGVVERFWLQADAGVCVLAGLGLSWLVCCLTGHLGKGTVWNTGAWILTAGLISHMISLNHRDCDQSSNDVVDRFSREVVLSLPQGSLVLTRGDLPGNTLRYQHYCQSLRPDLSLVDQEMMTYNWYVAKLQRHLPGVTFPGHRWDPVNAVEKKTFSIEQFLKRNLQPVFVCIGLTEGDPSWEGSFSRWPWGVCEQLLPVKTPFDPKKWAQKTHNLYNWSEPHDSFHPGSWERVANEEMWQARMKTAFFLFDLAENAEKEQQGRLYEISYKLYCQIVDSQVDYPANWDKNLALAAERLLQSGGRGYGLDSLMSRSIRHFSRYLKREPSDPQSKAIRSIITHLRKEREKFRDRQKA", "length": 651, "header": "tr|A0AC58HPF1-1|A0AC58HPF1_DANRE Computationally mapped isoform of Protein O-mannosyl-transferase TMEM260 isoform X4 OS=Danio rerio OX=7955 GN=tmem260 PE=4 SV=1 CANONICAL=E7F5M2-1" }, "locus": {} }, { "isoform_ac": "E7F5M2-1", "url": "https://www.uniprot.org/uniprotkb/E7F5M2/entry#E7F5M2-1", "sequence": { "sequence": "MSSDRWTWSLTGATVAGVSALYVGCAPRAVPGGDSGELITAACELGVAHPPGYPLFTMMSSLMLSLLPLSSPAHSINVLCAVFGAGASGALCFTVCRVAEPGPGAVLAGGVFAVSRLVWQWSVVAEVFSLNNLFVGVLFSLSACFHCADTVQQKKKFALWGALFCGLSLCNQHTLVLYVVVIIPWALLHLYTHNGLSFFDLVSLGTCFLAGFVPYMYLPVSSYLNRARWSWGDQTSVHGLLTHLLRAEYGTFSLAKTNESLNLLEMLRAQWNHCVNDLTVPVLALALLGMLLSLRSRLRCIFVCLIVTMVSIYSVFFAWRANLNIEKPLLLGVVERFWLQADAGVCVLAGLGLSWLVCCLTGHLGKGTVWNTGAWILTAGLISHMISLNHRDCDQSSNDVVDRFSREVVLSLPQGSLVLTRGDLPGNTLRYQHYCQSLRPDLSLVDQEMMTYNWYVAKLQRHLPGVTFPGHRWDPVNAVEKKTFSIEQFLKRNLHRPVFVCIGLTEGDPSWEGSFSRWPWGVCEQLLPVKTPFDPKKWAQKTHNLYNWSEPHDSFHPGSWERVANEEMWQARMKTAFFLFDLAENAEKEQQGRLYEISYKLYCQIVDSQVDYPANWDKNLALAAERLLQSGGRGYGLDSLMSRSIRHFSRYLKREPSDPQSKAIRSIITHLRKEREKFRDRQKA", "length": 684, "header": "tr|E7F5M2-1|E7F5M2_DANRE Isoform 1 of Protein O-mannosyl-transferase TMEM260 isoform X1 OS=Danio rerio OX=7955 GN=tmem260 PE=4 SV=1 CANONICAL=E7F5M2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:559650", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559650", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YZN2-1", "protein_name": "Transmembrane protein 260", "gene_name": "TMEM260", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGAGSGSGAAAVAAAGAVGAAVVAVYAGTLPPGLPGGDAGELITAAYELGVAHPPGYPLFTLLAGLAMRLLPGGAAAGRVNLLCAVLGAAAAALLFYTVLRLSGSYAGGILAAGVFSFSRLTWQWSITAEVFSLNNLFVGLLMALTVHFEEASTAKERSKIARLGAFCCGLSLCNQHTIVLYIACIVPWVLFLLFRKMELSLGHLLKLGLCFLAGLLPYLYLPASSYLDRARWTWGDQTTFQGFLTHFLREEYGTFNLAKSESGSSMREMLVFQLEQMRSDLSLPVLALALIACFSTALPIKQQKSPVICLFAGMLCVYSLFFAWRANLDVTKPLFLGVVERFWMQSNVAVAVLAGLGLAALMSLGGAVLQGSRVLPWLEWLSAGALVAAQVWANYRDCDQSNNYIVDKFARNLLSSMPMGAVILLRGDLPGNALRYLHYVEGVRPDITLVDQEMMTYEWYLPKLAKHLPGVHFPGNRWNPVEGILPDGTLVFNLHHFLKANKHKEVFVCIGLHEGDSTWRRSYSLWPWGTCEKLVPTDAVFDPGEWIRLTRNLYNWTEEYGSFKPSSWEAVANEEMWQARMKTAFFIFGLAETASVPAEMKSQLYTLAYTLYKEIVSSHPHHPVNWHKNYAIACERMLRLHRVGEDPEVLLSETVKHFLLYTQKAEDDPQRQDILQAVNHLQKELQGLRGMKAELKRQAG", "length": 701 }, "evidence": [ { "id": "E7F5M2", "url": "https://omabrowser.org/oma/group/E7F5M2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1M7C0-1", "protein_name": "Transmembrane protein 260", "gene_name": "Tmem260", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLHGDGGGPAAGAGPWRSGGLCGSVAVFAAVAAVFTLTLPRSLPGGDSGELITAAHELGVAHPPGYPLFTLVANLAITLFPFGSVAYRVNLLCGLFGAVAASLLFFTVFRLSGSRAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVRFEEATAAKERSKIAAIGAFSCGLSLCNQHTIVLYVLCIIPWILFRLLKEKELTLSLLLKLALAFSAGLLPYVYLPVSSYLSHARWTWGDQTTLRGFLTHFLREEYGTFSLAKSEVGSSASTVLLSQIINMKTELSFNIQALAVWANVCLPRKDRRKSSVVWLFTGMLCVYSLFFTWRANLDISKPLFMGVVERFWMQSNAVVAVLAGLGLATLVSETSRVLSWNGVRNLEWLSAALFIAYQVYSNYSICDQRTNNVIDQFARNLLNSMPPDAIILLRGDLPGNALRYLHYCEGLRPDVSLVDQEMMTYEWYLPKVARHLPGVHFPGDRWNPVEGVLPSGMVTFNLYHFLEMNKQKETFVCIGIHEGDPTWKKDYSLWPWGSCDKLVPSKIVFNPEEWIEHTRTIYNWTEEYGRFDPSSWESVANEEMWQARMKTPFFIFSLAESAAVPADVKAQLYTHAYKLYKEIVYLQEEHPVNWHKNYAIACERMLRLPGTGEDPEVLLSETIRHFHLYTQKAQNDPQRASIMAALKHLRRELRSLRNTKEV", "length": 703 }, "evidence": [ { "id": "HGNC:20185", "url": "https://alliancegenome.org/gene/HGNC:20185#orthology", "database": "AGR" }, { "id": "MGI:2443219", "url": "https://alliancegenome.org/gene/MGI:2443219#orthology", "database": "AGR" }, { "id": "E7F5M2", "url": "https://omabrowser.org/oma/group/E7F5M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1N5A9-1", "protein_name": "Transmembrane protein 260", "gene_name": "TMEM260", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MATAGARLGGQAARVGARGAGGLCGGVAVFAAVAAVFTLTLPPSLPGGDSGELITAAHELGVAHPPGYPLFTLVAKLAILLFPFGSVAYRVNLLCGLFGAAAAALLFFTVFRLSGSYAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVHFEEAATAQERSKIAKIGALCCGLSLCNQHTIVLYVLCIIPWILFRLLKEKELSPGSLLKLSLCFSAGLLPYIYLPVSSYLNQARWTWGDQTTLLGFLTHFLREEYGTFSLAKSEIGSSMSEILLSQVTNMRTQLSFNIQALAVWANICLTRKDRQSPSLVWLFTGMFCIYSLFFAWRANLDISKPLFMGVVERFWMQSNAVVAVLAGIGLAALVSESNRVLNTNGLQYLEWLSAILFVTCQIYSNYSICDQRTNYVIDKFAKNLLSSMPRDAIILLRGDLPGNSLRYMHYCEGLRPDISLVDQEMMTYEWYLPKMAKHLPGVKFPGNRWNPVEGILSSGMVTFNLYHFLEVNKQKETFVCIGIHEGDPTWKKNYSLWPWGSCDKLVSSEIVFNPEEWIKLTRNIYNWTESYGRFDPSSWESVANEEMWQARMKTPFFIFNLAESASLPSNVKAQLYTHAYNLYKEIVYLRKEHPVNWHKNYAISCERMLRLQERSADPEVLLSETIRHFRLYTRKAQNDPQLADISVALKHLRKELRSLRNMKNG", "length": 704 }, "evidence": [ { "id": "E7F5M2", "url": "https://omabrowser.org/oma/group/E7F5M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SSM4-1", "protein_name": "Transmembrane protein 260", "gene_name": "TMEM260", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGLHGDGGGLAEGPAARVGPRRSRGLRGGVAVFAAVAAVFTLTLPPSVPGGDSGELITAAHELGVAHPPGYPLFTLVAKLAIILFPFGSVAYRVNLLCGLFGAVAAALLFFTVFRLSGSYAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVHFEEAATSQERSKIAKIGAFCCGLSLCNQHTIVLYVLCIIPWILFRLLKEKELSLGSLLNLSLFFSAGLLPYIYLPISSYLHQARWTWGDQTTLLGFLTHFLREEYGTFSLAKSEIGSSMSEILLSQLTNMRTQLSFNIQALAVWANICLARKDRQNPPLAWLFTGMFCIYSLFFAWRANLDISKPLFMGVVERFWMQSNAVVAVLAGIGLAALVSESNRVLNTNGLQFLEWLSATLFVTYQIYSNYSICDQRTNYVIDKFAKNLLASMPQDAIILLRGDLPGNSLRYLHYCEGLRPDISLVDQEMMTYEWYLPKMAKHLPGVKFPGNRWNPVEGILPSGMVTFNLYHFLKINKQKETFVCIGIHEGDPTWKKNYSLWPWGSCDKLVSSEIAFNPEEWIKLTRNIYNWTEEYGRFDPSSWESVANEEMWQARMKTPFFIFNLAETTSLPSDVKAQLYTHAYNLYKEIVYLRKEHPVNWHKNYAIACERMLRLQESGADPEVLLSETIRHFRLYTQKARNDPQLADISAALKHLRKELQSLRNRKNV", "length": 707 }, "evidence": [ { "id": "E7F5M2", "url": "https://omabrowser.org/oma/group/E7F5M2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8BMD6-1", "protein_name": "Protein O-mannosyl-transferase TMEM260", "gene_name": "Tmem260", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLHGDGGSPAAGAGPWRSGALRGSVAVFASVAAVFTLTLPRSLPGGDSGELITAAHELGVAHPPGYPLFTLLASLTITLFPFGSVAYRVNLLCGLFGAVAASLLFYTVFRLSGSHAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVRFEEATAAKERSKIAAIGAFSCGLSLCNQHTIVLYILCIIPWILFRLLKEKELTLSLLLRLTLAFSAGLLPYVYLPVSSYLSRARWTWGDQTTLRGFLTHFFREEYGTFSLAKSEVGSSVSTVLLSQVINMKTELSFNIQALAVWANICLARKDRRKSSVVWLFTGMLCLYSLFFAWRANLDISKPLFMGVVERFWLQSNAVVAVLAGLGLATLVSETNRVLHCTGIRNLEWLSAALFVAYQVYSNYSICDQRTNNVIDQFARNLLDSMPQDAIILLRGDLPGNALRYLHYCEGLRPDVSLVDQEMMTYEWYLPKMARHLPGVHFPGDRWNPVEGVLPSGMVTFNLYHFLEMNKQKETFVCIGIHEGDPTWKKDYSLWPWGSCDKLVPSKIVFNPEEWIERTRAIYNWTEAYERFGPSSWESVANEEMWQARMKTPFFIFSLAESAAVPADVKAQLYTHAYKLYKEIVYLQEEHPVNWHKNYAIACERMLRLPGTGIDPEVLLSEAIRHFHLYTQKAQNDPQRADIIAALKHLRRELQSLRNIKKV", "length": 703 }, "evidence": [ { "id": "HGNC:20185", "url": "https://alliancegenome.org/gene/HGNC:20185#orthology", "database": "AGR" }, { "id": "MGI:2443219", "url": "https://alliancegenome.org/gene/MGI:2443219#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4198", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4198#orthology", "database": "AGR" }, { "id": "E7F5M2", "url": "https://omabrowser.org/oma/group/E7F5M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8MXQ3-1", "protein_name": "Protein O-mannosyl-transferase tmem260", "gene_name": "", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MNNSPTLSNTRNRKNNNNNSNSNSNSNNNNNNNNNNNNNSNNNNNNNNNVNRNVNNRNNNNNNIINVNNNVSSTTMNMAKDFMNWNDGIIEREDTQLQQQKDRCFKILKKSTIACIVLLFISCTIIYSMTQYPSVSGGDAGELIVVAHQFGVAHPPGYPLFTFLGYIFSHIIPSNTLSVAWKISFMSSMIGSIASIFIYLTVYLWVNNHWCGLLSAYMFTFSPLIWMYQIQGEVFSMNNMFVAMLMFLGVWYTRVRIFENERYNTAFWTSERIAYLSAFSCAIGLTNQHTLVLIVIPFAFWLMFISGRDQLWNIKILSNLVFYTLIGLSPYLLLFITPKLNRVKYSWGNTSTLRGFIKHFLREEYGTLQLYGGDGGVISLFTKISIYIENLIIQFGYIGLALSLIGLLNLLLGYNIRTFKWKSFGTMIIFSFLFYITFFFNLCNLPIDKPLYRGVFLRFFMQPNVIISITMGLGIKSIFGFLNRIQRDGGTAATTTTTISKIQKYLLPIIIILLVGNQIGFNYNLQDQSDNYSFYDYGHSVLDGLPRNTLLLVGGDLVTNVPMYLHLCEKVRPDIDILSMEIMSWEWFKITQSPLFQRVKFPGNVYHPYIPDGYSLKDFLDANINDRPIYIGGDFKSGDSSFQNDYYTISKGLTSQIIPKKDSHKFNTFKIIKTTFSTFPSFHIPNNTEKYPNDSWEHFMMEEMAVSLERAAETLLKEYLSQQNTESFKALELSVEILEKALTYVNDKCWSLKHLGICFDHLRYRVVQNVNNNNQQAQNKASNYSKQLLYFWKKYINQCTHEENTDQDWETIKKVIQLI", "length": 819 }, "evidence": [ { "id": "E7F5M2", "url": "https://omabrowser.org/oma/group/E7F5M2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q9NX78-1", "protein_name": "Protein O-mannosyl-transferase TMEM260", "gene_name": "TMEM260", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSPHGDGRGQAQGRAVRVGLRRSGGIRGGVAVFAAVAAVFTFTLPPSVPGGDSGELITAAHELGVAHPPGYPLFTLVAKLAITLFPFGSIAYRVNLLCGLFGAVAASLLFFTVFRLSGSSAGGILAAGVFSFSRLTWQWSIAAEVFSLNNLFVGLLMALTVHFEEAATAKERSKVAKIGAFCCGLSLCNQHTIILYVLCIIPWILFQLLKKKELSLGSLLKLSLYFSAGLLPYVHLPISSYLNHARWTWGDQTTLQGFLTHFLREEYGTFSLAKSEIGSSMSEILLSQVTNMRTELSFNIQALAVCANICLATKDRQNPSLVWLFTGMFCIYSLFFAWRANLDISKPLFMGVVERFWMQSNAVVAVLAGIGLAAVVSETNRVLNSNGLQCLEWLSATLFVVYQIYSNYSVCDQRTNYVIDKFAKNLLTSMPHDAIILLRGDLPGNSLRYMHYCEGLRPDISLVDQEMMTYEWYLPKMAKHLPGVNFPGNRWNPVEGILPSGMVTFNLYHFLEVNKQKETFVCIGIHEGDPTWKKNYSLWPWGSCDKLVPLEIVFNPEEWIKLTKSIYNWTEEYGRFDPSSWESVANEEMWQARMKTPFFIFNLAETAHMPSKVKAQLYAQAYDLYKEIVYLQKEHPVNWHKNYAIACERMLRLQARDADPEVLLSETIRHFRLYSQKAPNDPQQADILGALKHLRKELQSLRNRKNV", "length": 707 }, "evidence": [ { "id": "HGNC:20185", "url": "https://alliancegenome.org/gene/HGNC:20185#orthology", "database": "AGR" }, { "id": "MGI:2443219", "url": "https://alliancegenome.org/gene/MGI:2443219#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4198", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4198#orthology", "database": "AGR" }, { "id": "E7F5M2", "url": "https://omabrowser.org/oma/group/E7F5M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "dolichyl-phosphate-mannose-protein mannosyltransferase activity", "id": "GO:0004169", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004169", "evidence": [ { "database": "UniProtKB", "id": "E7F5M2", "url": "https://www.uniprot.org/uniprotkb/E7F5M2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E7F5M2", "url": "https://www.uniprot.org/uniprotkb/E7F5M2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "central nervous system development", "id": "GO:0007417", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007417", "evidence": [ { "database": "UniProtKB", "id": "E7F5M2", "url": "https://www.uniprot.org/uniprotkb/E7F5M2" } ], "pmid": "" }, { "name": "protein maturation", "id": "GO:0051604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051604", "evidence": [ { "database": "UniProtKB", "id": "E7F5M2", "url": "https://www.uniprot.org/uniprotkb/E7F5M2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 258, "end_pos": 260, "annotation": "n_glycosylation_sequon" }, { "start_pos": 547, "end_pos": 549, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F5M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5M2" }, { "id": "PF11028", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11028" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein O-mannosyl-transferase TMEM260 N-terminal", "eco_id": "ECO_0000259", "start_pos": 34, "end_pos": 188, "start_aa": "Asp", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 258, "end_pos": 260 }, { "start_pos": 547, "end_pos": 549 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FEI6-1", "uniprot_ac": "E7FEI6", "uniprot_id": "E7FEI6_DANRE", "mass": { "chemical_mass": 108023.0, "monoisotopic_mass": 108023.0 }, "refseq": { "ac": "XP_689729", "name": "SLIT-ROBO Rho GTPase-activating protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689729" }, "gene_names": [ { "name": "arhgap4b", "type": "recommended", "evidence": [ { "id": "E7FEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FEI6" } ] }, { "name": "arhgap4b", "type": "synonym", "evidence": [ { "id": "XP_689729", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689729" } ] } ], "protein_names": [ { "name": "SLIT-ROBO Rho GTPase-activating protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_689729", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689729" }, { "id": "E7FEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FEI6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_689729.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_689729", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689729" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FEI6", "url": "https://www.uniprot.org/uniprotkb/E7FEI6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "arhgap4b", "url": "https://www.uniprot.org/uniprotkb/E7FEI6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090311-38", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090311-38", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000015003", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000015003", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04383", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04383", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd07656", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07656", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "561231", "url": "https://www.ncbi.nlm.nih.gov/gene/561231", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001060", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001060", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027267", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027267", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR031160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR031160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051627", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051627", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561231", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561231", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ECAGARG", "url": "https://omabrowser.org/oma/group/ECAGARG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2B8X5", "url": "https://www.orthodb.org/?gene=A0A8M2B8X5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AY98", "url": "https://www.orthodb.org/?gene=A0A8M3AY98", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FEI6", "url": "https://www.orthodb.org/?gene=E7FEI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00018", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00018", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00611", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00611", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14604", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14604", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_689729", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689729", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B8X5", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B8X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B8X5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B8X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AY98", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AY98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AY98-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AY98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TAT5", "url": "https://www.uniprot.org/uniprotkb/A0AB32TAT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TAT5-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TAT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IKW6", "url": "https://www.uniprot.org/uniprotkb/A0AC58IKW6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IKW6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IKW6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IKZ4", "url": "https://www.uniprot.org/uniprotkb/A0AC58IKZ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IKZ4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IKZ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FEI6", "url": "https://www.uniprot.org/uniprotkb/E7FEI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FEI6-1", "url": "https://www.uniprot.org/uniprotkb/E7FEI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090311-38", "url": "https://zfin.org/ZDB-GENE-090311-38", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTSHGKLRKEKGSLAEYETQIKEVRGQLSEQLKILDAQLEVKTQQLQDMSEYLRRRGEIEAEYARSLEKLSEKFTVKTKRKEQLDLSVAQCWSVLLTQTRQESRDHSSLSELCGNTLTQRLSHCIEDTHRLAKRSKEVGLQMQDELLKITTELQTALKTYHQYHIDCLAAEGKLKEATRLEEKQTGKSADLGLSQSGGQRRSSVKKMERLMEKRQGKVQETQLKCTKARNDYLLNLAAANASMNKYYLQDICTLIDCTDLGYHLSVTRVIRGYLSYKNRIVQNMKNGLQQLDTAVTGLNQGQDRDSLLQAHNIAFCLPFRFQYQPHEGDQVCEVSAEGQVRYELDTRFQQLQSRLASVTLETDEVSKTLKATHSNLLESVCDDDCNPAPDASSTPSVEGTADGTGTKPSLAKRRANQQDTETFYFTKVKEHVSGSSLISKLQAKHDLLKEAIQKAEAIDSDPSRMQPGRAVRVRKARPCSQYNHKLFSGDMLSFIQSSGQQIPLVVESCIRFINLHGLHHEGIFRVPGSQTEVNHIRDAFERGEDPLTDSESDIDSVAGVLKLYFRGLEKPLFPEESFSQLMECVQMENMTEKVAQIKSVVSSYPRPVIIVMRYLFAFLHHVSQYSDENMMQPYNLAVCFGPSLLRGVEMGGDEVTLAPQINELVKTMILHHENIFPGPSELPGPVYEKCMTLEQEYCEPITEEGEGDPEHLPSEDEWEAVAMFDYVARSAAELSFKQGEHLLLHSKASADWWRGEVGGMKGLIPHKYISVVEGMERKDRGKKEDSRGGSTGNLAEEQQQQSEHSTRMRVNSDSASLPGRQRTGSGSSGSIGGGNSGNMSPVRKLTLQVPEGRLMLPPQTTAVARQFSGHQERRHTLDSLRPVGAPDRQTVHIDKEVSRQMNSVFKELLSRQPPQEALGSSASPSSPPASVPSIPSVSSAAARPPVKKGGFGLRSRGLFKPQDQQD", "length": 966, "header": "tr|E7FEI6-1|E7FEI6_DANRE Isoform 1 of SLIT-ROBO Rho GTPase-activating protein 3 isoform X1 OS=Danio rerio OX=7955 GN=arhgap4b PE=4 SV=2 CANONICAL=E7FEI6-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B8X5-1", "url": "https://www.uniprot.org/uniprotkb/E7FEI6/entry#A0A8M2B8X5-1", "sequence": { "sequence": "MTSHGKLRKEKGSLAEYETQIKEVRGQLSEQLKILDAQLEVKTQQLQDMSEYLRRRGEIEAEYARSLEKLSEKFTVKTKRKEQLDLSVAQCWSVLLTQTRQESRDHSSLSELCGNTLTQRLSHCIEDTHRLAKRSKEVGLQMQDELLKITTELQTALKTYHQYHIDCLAAEGKLKEATRLEEKQTGKSADLGLSQSGGQRRSSVKKMERLMEKRQGKVQETQLKCTKARNDYLLNLAAANASMNKYYLQDICTLIDCTDLGYHLSVTRVIRGYLSYKNRIVQNMKNGLQQLDTAVTGLNQGQDRDSLLQAHNIAFCLPFRFQYQPHEGDQVCEVSAEGQVRYELDTRFQQLQSRLASVTLETDEVSKTLKATHSNLLESVCDDDCNPAPDASSTPSVEGTADGTGTKPSLAKRRANQQDTETFYFTKVKEHVSGSSLISKLQAKHDLLKEAIQKAEAIDSDPSRRRRRMSRTQSSGQQIPLVVESCIRFINLHGLHHEGIFRVPGSQTEVNHIRDAFERGEDPLTDSESDIDSVAGVLKLYFRGLEKPLFPEESFSQLMECVQMENMTEKVAQIKSVVSSYPRPVIIVMRYLFAFLHHVSQYSDENMMQPYNLAVCFGPSLLRGVEMGGDEVTLAPQINELVKTMILHHENIFPGPSELPGPVYEKCMTLEQEYCEPITEEGEGDPEHLPSEDEWEAVAMFDYVARSAAELSFKQGEHLLLHSKASADWWRGEVGGMKGLIPHKYISVVEGMERKDRGKKEDSRGGSTGNLAEEQQQQSEHSTRMRVNSDSASLPGRQRTGSGSSGSIGGGNSGNMSPVRKLTLQVPEGRLMLPPQTTAVARQFSGHQERRHTLDSLRPVGAPDRQTVHIDKEVSRQMNSVFKELLSRQPPQEALGSSASPSSPPASVPSIPSVSSAAARPPVKKGGFGLRSRGLFKPQDQQD", "length": 943, "header": "tr|A0A8M2B8X5-1|E7FEI6_DANRE Computationally mapped isoform of SLIT-ROBO Rho GTPase-activating protein 3 isoform X1 OS=Danio rerio OX=7955 GN=arhgap4b PE=4 SV=1 CANONICAL=E7FEI6-1" }, "locus": {} }, { "isoform_ac": "A0A8M3AY98-1", "url": "https://www.uniprot.org/uniprotkb/E7FEI6/entry#A0A8M3AY98-1", "sequence": { "sequence": "MTSHGKLRKEKGSLAEYETQIKEVRGQLSEQLKILDAQLEVKTQQLQDMSEYLRRRGEIEAEYARSLEKLSEKFTVKTKRKEQLDLSVAQCWSVLLTQTRQESRDHSSLSELCGNTLTQRLSHCIEDTHRLAKRSKEVGLQMQDELLKITTELQTALKTYHQYHIDCLAAEGKLKEATRLEEKQTGKSADLGLSQSGGQRRSSVKKMERLMEKRQGKVQETQLKCTKARNDYLLNLAAANASMNKYYLQDICTLIDCTDLGYHLSVTRVIRGYLSYKNRIVQNMKNGLQQLDTAVTGLNQGQDRDSLLQAHNIAFCLPFRFQYQPHEGDQVCEVSAEGQVRYELDTRFQQLQSRLASVTLETDEVSKTLKATHSNLLESVCDDDCNPAPDASSTPSVEGTADGTGTKPSLAKRRANQQDTETFYFTKVKEHVSGSSLISKLQAKHDLLKEAIQKAEAIDSDPSRMQPGRAVRVRKARPCSQYNHKLFSGDMLSFIQSSGQQIPLVVESCIRFINLHGLHHEGIFRVPGSQTEVNHIRDAFERGEDPLTDSESDIDSVAGVLKLYFRGLEKPLFPEESFSQLMECVQMENMTEKVAQIKSVVSSYPRPVIIVMRYLFAFLHHVSQYSDENMMQPYNLAVCFGPSLLRGVEMGGDEVTLAPQINELVKTMILHHENIFPGPSELPGPVYEKCMTLEQEYCEPITEEGEGDPEHLPSEDAELSFKQGEHLLLHSKASADWWRGEVGGMKGLIPHKYISVVEGMERKDRGKKEDSRGGSTGNLAEEQQQQSEHSTRMRVNSDSASLPGRQRTGSGSSGSIGGGNSGNMSPVRKLTLQVPEGRLMLPPQTTAVARQFSGHQERRHTLDSLRPVGAPDRQTVHIDKEVSRQMNSVFKELLSRQPPQEALGSSASPSSPPASVPSIPSVSSAAARPPVKKGGFGLRSRGLFKPQDQQD", "length": 951, "header": "tr|A0A8M3AY98-1|E7FEI6_DANRE Computationally mapped isoform of SLIT-ROBO Rho GTPase-activating protein 3 isoform X1 OS=Danio rerio OX=7955 GN=arhgap4b PE=4 SV=1 CANONICAL=E7FEI6-1" }, "locus": {} }, { "isoform_ac": "A0AB32TAT5-1", "url": "https://www.uniprot.org/uniprotkb/E7FEI6/entry#A0AB32TAT5-1", "sequence": { "sequence": "MTSHGKLRKEKGSLAEYETQIKEVRGQLSEQLKILDAQLEVKTQQLQDMSEYLRRRGEIEAEYARSLEKLSEKFTVKTKRKEQLDLSVAQCWSVLLTQTRQESRDHSSLSELCGNTLTQRLSHCIEDTHRLAKRSKEVGLQMQDELLKITTELQTALKTYHQYHIDCLAAEGKLKEATRLEEKQTGKSADLGLSQSGGQRRSSVKKMERLMEKRQGKVQETQLKCTKARNDYLLNLAAANASMNKYYLQDICTLIDCTDLGYHLSVTRVIRGYLSYKNRIVQNMKNGLQQLDTAVTGLNQGQDRDSLLQAHNIAFCLPFRFQYQPHEGDQVCEVSAEGQVRYELDTRFQQLQSRLASVTLETDEVSKTLKATHSNLLESVCDDDCNPAPDASSTPSVEGTADGTGTKPSLAKRRANQQDTETFYFTKVKEHVSGSSLISKLQAKHDLLKEAIQKAEAIDSDPSRRRRRMSRTQSSGQQIPLVVESCIRFINLHGLHHEGIFRVPGSQTEVNHIRDAFERGEDPLTDSESDIDSVAGVLKLYFRGLEKPLFPEESFSQLMECVQMENMTEKVAQIKSVVSSYPRPVIIVMRYLFAFLHHVSQYSDENMMQPYNLAVCFGPSLLRGVEMGGDEVTLAPQINELVKTMILHHENIFPGPSELPGPVYEKCMTLEQEYCEPITEEGEGDPEHLPSEDAELSFKQGEHLLLHSKASADWWRGEVGGMKGLIPHKYISVVEGMERKDRGKKEDSRGGSTGNLAEEQQQQSEHSTRMRVNSDSASLPGRQRTGSGSSGSIGGGNSGNMSPVRKLTLQVPEGRLMLPPQTTAVARQFSGHQERRHTLDSLRPVGAPDRQTVHIDKEVSRQMNSVFKELLSRQPPQEALGSSASPSSPPASVPSIPSVSSAAARPPVKKGGFGLRSRGLFKPQDQQD", "length": 928, "header": "tr|A0AB32TAT5-1|E7FEI6_DANRE Computationally mapped isoform of SLIT-ROBO Rho GTPase-activating protein 3 isoform X1 OS=Danio rerio OX=7955 GN=arhgap4b PE=4 SV=1 CANONICAL=E7FEI6-1" }, "locus": {} }, { "isoform_ac": "A0AC58IKW6-1", "url": "https://www.uniprot.org/uniprotkb/E7FEI6/entry#A0AC58IKW6-1", "sequence": { "sequence": "MTYLKRPYRKLRPLIATPPECSLVGQCVCGKPGPAPSTTTNSSLETCSPSFRRRRRMSRTQSSGQQIPLVVESCIRFINLHGLHHEGIFRVPGSQTEVNHIRDAFERGEDPLTDSESDIDSVAGVLKLYFRGLEKPLFPEESFSQLMECVQMENMTEKVAQIKSVVSSYPRPVIIVMRYLFAFLHHVSQYSDENMMQPYNLAVCFGPSLLRGVEMGGDEVTLAPQINELVKTMILHHENIFPGPSELPGPVYEKCMTLEQEYCEPITEEGEGDPEHLPSEDEWEAVAMFDYVARSAAELSFKQGEHLLLHSKASADWWRGEVGGMKGLIPHKYISVVEGMERKDRGKKEDSRGGSTGNLAEEQQQQSEHSTRMRVNSDSASLPGRQRTGSGSSGSIGGGNSGNMSPVRKLTLQVPEGRLMLPPQTTAVARQFSGHQERRHTLDSLRPVGAPDRQTVHIDKEVSRQMNSVFKELLSRQPPQEALGSSASPSSPPASVPSIPSVSSAAARPPVKKGGFGLRSRGLFKPQDQQD", "length": 531, "header": "tr|A0AC58IKW6-1|A0AC58IKW6_DANRE Computationally mapped isoform of SLIT-ROBO Rho GTPase-activating protein 1 isoform X5 OS=Danio rerio OX=7955 GN=arhgap4b PE=4 SV=1 CANONICAL=E7FEI6-1" }, "locus": {} }, { "isoform_ac": "A0AC58IKZ4-1", "url": "https://www.uniprot.org/uniprotkb/E7FEI6/entry#A0AC58IKZ4-1", "sequence": { "sequence": "MTYLKRPYRKLRPLIATPPECSLVGQCVCGKPGPAPSTTTNSSLETCSPSFRRRRRMSRTQSSGQQIPLVVESCIRFINLHGLHHEGIFRVPGSQTEVNHIRDAFERGEDPLTDSESDIDSVAGVLKLYFRGLEKPLFPEESFSQLMECVQMENMTEKVAQIKSVVSSYPRPVIIVMRYLFAFLHHVSQYSDENMMQPYNLAVCFGPSLLRGVEMGGDEVTLAPQINELVKTMILHHENIFPGPSELPGPVYEKCMTLEQEYCEPITEEGEGDPEHLPSEDAELSFKQGEHLLLHSKASADWWRGEVGGMKGLIPHKYISVVEGMERKDRGKKEDSRGGSTGNLAEEQQQQSEHSTRMRVNSDSASLPGRQRTGSGSSGSIGGGNSGNMSPVRKLTLQVPEGRLMLPPQTTAVARQFSGHQERRHTLDSLRPVGAPDRQTVHIDKEVSRQMNSVFKELLSRQPPQEALGSSASPSSPPASVPSIPSVSSAAARPPVKKGGFGLRSRGLFKPQDQQD", "length": 516, "header": "tr|A0AC58IKZ4-1|A0AC58IKZ4_DANRE Computationally mapped isoform of SLIT-ROBO Rho GTPase-activating protein 3 isoform X6 OS=Danio rerio OX=7955 GN=arhgap4b PE=4 SV=1 CANONICAL=E7FEI6-1" }, "locus": {} }, { "isoform_ac": "E7FEI6-1", "url": "https://www.uniprot.org/uniprotkb/E7FEI6/entry#E7FEI6-1", "sequence": { "sequence": "MTSHGKLRKEKGSLAEYETQIKEVRGQLSEQLKILDAQLEVKTQQLQDMSEYLRRRGEIEAEYARSLEKLSEKFTVKTKRKEQLDLSVAQCWSVLLTQTRQESRDHSSLSELCGNTLTQRLSHCIEDTHRLAKRSKEVGLQMQDELLKITTELQTALKTYHQYHIDCLAAEGKLKEATRLEEKQTGKSADLGLSQSGGQRRSSVKKMERLMEKRQGKVQETQLKCTKARNDYLLNLAAANASMNKYYLQDICTLIDCTDLGYHLSVTRVIRGYLSYKNRIVQNMKNGLQQLDTAVTGLNQGQDRDSLLQAHNIAFCLPFRFQYQPHEGDQVCEVSAEGQVRYELDTRFQQLQSRLASVTLETDEVSKTLKATHSNLLESVCDDDCNPAPDASSTPSVEGTADGTGTKPSLAKRRANQQDTETFYFTKVKEHVSGSSLISKLQAKHDLLKEAIQKAEAIDSDPSRMQPGRAVRVRKARPCSQYNHKLFSGDMLSFIQSSGQQIPLVVESCIRFINLHGLHHEGIFRVPGSQTEVNHIRDAFERGEDPLTDSESDIDSVAGVLKLYFRGLEKPLFPEESFSQLMECVQMENMTEKVAQIKSVVSSYPRPVIIVMRYLFAFLHHVSQYSDENMMQPYNLAVCFGPSLLRGVEMGGDEVTLAPQINELVKTMILHHENIFPGPSELPGPVYEKCMTLEQEYCEPITEEGEGDPEHLPSEDEWEAVAMFDYVARSAAELSFKQGEHLLLHSKASADWWRGEVGGMKGLIPHKYISVVEGMERKDRGKKEDSRGGSTGNLAEEQQQQSEHSTRMRVNSDSASLPGRQRTGSGSSGSIGGGNSGNMSPVRKLTLQVPEGRLMLPPQTTAVARQFSGHQERRHTLDSLRPVGAPDRQTVHIDKEVSRQMNSVFKELLSRQPPQEALGSSASPSSPPASVPSIPSVSSAAARPPVKKGGFGLRSRGLFKPQDQQD", "length": 966, "header": "tr|E7FEI6-1|E7FEI6_DANRE Isoform 1 of SLIT-ROBO Rho GTPase-activating protein 3 isoform X1 OS=Danio rerio OX=7955 GN=arhgap4b PE=4 SV=2 CANONICAL=E7FEI6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561231", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561231", "resource": "KEGG Pathway" }, { "id": "R-DRE-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-DRE-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-DRE-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JVF0-1", "protein_name": "Rho GTPase activating protein 4", "gene_name": "Arhgap4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAHGKLRRERGLQPEYEAQVKVMRGQLSEQLHCLELQGELRRDLLLELAEFMRRRAEVELEYSRGLDKLAERFTSRSGRLGGSSREQQSFRKEPTLLSPLHCWAMLLEHTRQQSRESATLSEVLAGPLAQRLSHIAEDVGRIVKKSKDLVQQLQDELLEVVSELQTQGYLAWASLQTKKTYHVYHLESMNAETKLREAERQEEKRSGKSALPTTTAASATTTITIETELHRKGSLKKGGRLVEKRQAKFLEHKLKCTKARNEYLLSLASVNAAVSNYYLHDILDLMDCCDTGFHLALEQALRSYTAAESRTQTSHMQGLGSLEEALEALDPPGDKAKVLEVHAMAFCPPLRFDYQPHEGDEVAEIQVEMELRDEILPRAQNIQSRLDQKTIETEEVNKTLKATLQALLEVVASEDGDILDSLQASPSTESLKSTSSDPGTRQAGRRRNQQQETETFYITKLQEYLSGRSILAKLQAKHEKLQEAIQRGNKEEQETSSWTQCTERKFHKSHHPYPGSQCTQRLFGGDLEKFIQSTGQPVPLVVKSCIRFINLNGLQHEGIFRVSGAQARILEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPLDMFNELLASAELEVVGERVELVSHLLSRLPRPVLVVLRYLFTFLNHLAQYSDENMMDSYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLILQPAWVFPPTAMLPGPIYEKCMAPPSASCLGDGQLESLAGEPELELKTGTKAQEDDSEGVVEAVACFAYTGRTAQELTFQQGDTLRLYARASSDWWRGEHAGVRGLIPHKYITLSEGDEKQMTGSGLQAMGESLSHPESVLTLEFTNRLELGTPPEALGPSGHRRHCLVPTSPEQHVEMDKAVAQNMDSVFKELLGKAAVRQGHGLASTASPSLGTRNLKPLACSSFSKNKVFSRGPGAPVSPSVSHPQGPDSTRKPV", "length": 965 }, "evidence": [ { "id": "MGI:2159577", "url": "https://alliancegenome.org/gene/MGI:2159577#orthology", "database": "AGR" }, { "id": "HGNC:674", "url": "https://alliancegenome.org/gene/HGNC:674#orthology", "database": "AGR" }, { "id": "E7FEI6", "url": "https://omabrowser.org/oma/group/E7FEI6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B1AUY3-1", "protein_name": "Rho GTPase activating protein 4", "gene_name": "Arhgap4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAHGKLRRERGLQPEYDAQVKEMRWQLSEQLHCLELQGELRRDLLQELAEFMRRRAEVELEYSRGLDKLAERFTSRSGRLGGSSQEQQSFRKEPTLLSPLHCWAVLLEHTRQQSRESAALSEVLAGPLAQRLSHISEDVGRIVKKSKDLVQQLQAELLEVVSELQTQGYFAWASLQTKKMYHVYHSESMNAETKLREAERQEEKRSGRSALSTTTTTSATTTTTTTTVETGPHRKSSLKKGGRLVEKRQAKYLEHKLKCTKARNEYLLSLASVNAAISNYYLHDILDLMDCCDTGFHLALEQALRSYTAAESRTQTSQMQGLGSLEEALEALDPPGDKAKVLEVHAMAFCPPLRFEYQPHEDDEVAEVLIEMELWDEILPRAQNIQSRLDQKTIETEEVNKTLKATLKALLEAVASEDGDILDSLQASPSTESLKSTSSDPGTRQTGRRRNQQQETETFYITKLQEYLSGRSILSKLQAKHEKLQEAIQQGNKEKQETSRTQCTERKFHKSHPPHPRFQYNQRLFGGDLEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQARISEIRDAFERGEDPLEKGCTVHDLDSVAGVLKLYFRSLEPPLFPLDMFNELLASAELEVVGERVEPVSHLLFKLPRPVLVVLRYLFTFLNHLAQYSDENMMDSYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLILQPARIFPPPAMLPGPIYEKCMAPPSASCLGDGQLESLIGEPELELKTGTTAQEDDQEGVLEAVACFAYTGRTAQELTFQRGDVLRLYARASSDWWRGEHAGVQGLIPHKYITLCEGDEKQMAGSGLQAMGESVSHPEGFLTLEFANRLELGTPPEALGPSRHRRPCLVPTSPEGHVEMDKAVAQNMNSVFKELLGKTAVRQGHGLASTASPSLGTLTPLACSSISKNKVFSRGPGAPISPSTSHPQGPDSTRKPV", "length": 965 }, "evidence": [ 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"MAAHGKLRRERGLQAEYETQVKEMRWQLSEQLRCLELQGELRRELLQELAEFMRRRAEVELEYSRGLEKLAERFSSRGGRLGSSREHQSFRKEPSLLSPLHCWAVLLQHTRQQSRESAALSEVLAGPLAQRLSHIAEDVGRLVKKSRDLEQQLQDELLEVVSELQTAKKTYQAYHMESVNAEAKLREAERQEEKRAGRSVPTTTAGATEAGPLRKSSLKKGGRLVEKRQAKFMEHKLKCTKARNEYLLSLASVNAAVSNYYLHDVLDLMDCCDTGFHLALGQVLRSYTAAESRTQASQVQGLGSLEEAVEALDPPGDKAKVLEVHATVFCPPLRFDYHPHDGDEVAEICVEMELRDEILPRAQNIQSRLDRQTIETEEVNKTLKATLQALLEVVASDDGDVLDSFQTSPSTESLKSTSSDPGSRQAGRRRGQQQETETFYLTKLQEYLSGRSILAKLQAKHEKLQEALQRGDKEEQEVSWTQYTQRKFQKSRQPRPSSQYNQRLFGGDMEKFIQSSGQPVPLVVESCIRFINLNGLQHEGIFRVSGAQLRVSEIRDAFERGEDPLVEGCTAHDLDSVAGVLKLYFRSLEPPLFPPDLFGELLASSELEATAERVEHVSRLLWRLPAPVLVVLRYLFTFLNHLAQYSDENMMDPYNLAVCFGPTLLPVPAGQDPVALQGRVNQLVQTLIVQPDRVFPPLTSLPGPVYEKCMAPPSASCLGDAQLESLGADNEPELEAEMPAQEDDLEGVVEAVACFAYTGRTAQELSFRRGDVLRLHERASSDWWRGEHNGMRGLIPHKYITLPAGTEKQVVGAGLQTAGESGSSPEGLLASELVHRPEPCTSPEAMGPSGHRRRCLVPASPEQHVEVDKAVAQNMDSVFKELLGKTSVRQGLGPASTTSPSPGPRSPKAPPSSRLGRNKGFSRGPGAPASPSASHPQGLDTTPKPH", "length": 946 }, "evidence": [ { "id": "MGI:2159577", "url": "https://alliancegenome.org/gene/MGI:2159577#orthology", "database": "AGR" }, { "id": "HGNC:674", "url": "https://alliancegenome.org/gene/HGNC:674#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090311-38", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090311-38#orthology", "database": "AGR" }, { "id": "E7FEI6", "url": "https://omabrowser.org/oma/group/E7FEI6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "E7FEI6", "url": "https://www.uniprot.org/uniprotkb/E7FEI6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E7FEI6", "url": "https://www.uniprot.org/uniprotkb/E7FEI6" } ], "pmid": "" }, { "name": "nervous system development", "id": "GO:0007399", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007399", "evidence": [ { "database": "UniProtKB", "id": "E7FEI6", "url": "https://www.uniprot.org/uniprotkb/E7FEI6" } ], "pmid": "" }, { "name": "negative regulation of cell migration", "id": "GO:0030336", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030336", "evidence": [ { "database": "UniProtKB", "id": "E7FEI6", "url": "https://www.uniprot.org/uniprotkb/E7FEI6" } ], "pmid": "" }, { "name": "regulation of synapse assembly", "id": "GO:0051963", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051963", "evidence": [ { "database": "UniProtKB", "id": "E7FEI6", "url": "https://www.uniprot.org/uniprotkb/E7FEI6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E7FEI6", "url": "https://www.uniprot.org/uniprotkb/E7FEI6" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7FEI6", "url": "https://www.uniprot.org/uniprotkb/E7FEI6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 240, "end_pos": 242, "annotation": "n_glycosylation_sequon" }, { "start_pos": 589, "end_pos": 591, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FEI6" }, { "id": "PS51741", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51741" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-BAR", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 303, "start_aa": "Lys", "end_aa": "Asp", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7FEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FEI6" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 489, "end_pos": 676, "start_aa": "Gly", "end_aa": "Phe", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7FEI6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FEI6" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 715, "end_pos": 774, "start_aa": "Glu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 240, "end_pos": 242 }, { "start_pos": 589, "end_pos": 591 }, { "start_pos": 838, "end_pos": 840 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E9QIK0-1", "uniprot_ac": "E9QIK0", "uniprot_id": "E9QIK0_DANRE", "mass": { "chemical_mass": 20800.0, "monoisotopic_mass": 20800.0 }, "refseq": { "ac": "NP_001373412", "name": "emerin (Emery-Dreifuss muscular dystrophy) isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373412" }, "gene_names": [ { "name": "emd", "type": "recommended", "evidence": [ { "id": "E9QIK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QIK0" } ] }, { "name": "emd", "type": "synonym", "evidence": [ { "id": "NP_001373412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373412" } ] } ], "protein_names": [ { "name": "Emerin (Emery-Dreifuss muscular dystrophy) isoform 1", "type": "synonym", "evidence": [ { "id": "E9QIK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QIK0/entry#names_and_taxonomy" } ] }, { "name": "emerin (Emery-Dreifuss muscular dystrophy) isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001373412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373412" } ] }, { "name": "emerin (Emery-Dreifuss muscular dystrophy)", "type": "synonym", "evidence": [ { "id": "NP_001373412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373412" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01009608.1, BC135026.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On or before Aug 24, 2020 this sequence version replaced XP_021329294.1, XP_001924046.1, XP_021330202.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).", "evidence": [ { "database": "RefSeq", "id": "NP_001373412", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373412" } ] } ], "disease": [ { "disease_id": "DOID:0070246", "recommended_name": { "id": "DOID:0070246", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070246", "name": "X-linked Emery-Dreifuss muscular dystrophy 1", "description": "An Emery-Dreifuss muscular dystrophy that has_material_basis_in an X-linked recessive mutation of EMD on chromosome Xq28." }, "synonyms": [ { "id": "DOID:0070246", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070246", "name": "EDMD1", "description": "" }, { "id": "DOID:0070246", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070246", "name": "EMD1", "description": "" }, { "id": "DOID:0070246", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070246", "name": "Emery-Dreifuss muscular dystrophy 1, X-linked", "description": "" }, { "id": "DOID:0070246", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070246", "name": "humeroperoneal neuromuscular disease", "description": "" }, { "id": "DOID:0070246", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070246", "name": "scapuloperoneal syndrome, X-linked", "description": "" }, { "id": "DOID:0070246", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070246", "name": "muscular dystrophy, tardive, Dreifuss-Emery type, with contractures", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "Emery-Dreifuss muscular dystrophy 1, X-linked", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "EDMD1", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "EMD1", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "Emery-Dreifuss muscular dystrophy 1, X-linked", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "Humeroperoneal neuromuscular disease", "description": "" }, { "id": "MIM:310300", "resource": "MIM", "url": "https://www.omim.org/entry/310300", "name": "Emery-Dreifuss muscular dystrophy 1, X-linked", "description": "Emery-Dreifuss muscular dystrophy 1, X-linked" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070246", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070246" } ] }, { "disease_id": "DOID:11726", "recommended_name": { "id": "DOID:11726", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11726", "name": "Emery-Dreifuss muscular dystrophy", "description": "A muscular dystrophy that chiefly affects muscles used for movement (skeletal) and heart (cardiac) muscle." }, "synonyms": [ { "id": "DOID:11726", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11726", "name": "EDMD", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "Emery-Dreifuss muscular dystrophy 1, X-linked", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "EDMD1", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "EMD1", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "Emery-Dreifuss muscular dystrophy 1, X-linked", "description": "" }, { "id": "MONDO:0100531", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0100531", "name": "Humeroperoneal neuromuscular disease", "description": "" }, { "id": "MIM:310300", "resource": "MIM", "url": "https://www.omim.org/entry/310300", "name": "Emery-Dreifuss muscular dystrophy 1, X-linked", "description": "Emery-Dreifuss muscular dystrophy 1, X-linked" } ], "unlinked_id_list": [], "evidence": [ { "id": "11726", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11726" } ] }, { "disease_id": "DOID:12930", "recommended_name": { "id": "DOID:12930", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12930", "name": "dilated cardiomyopathy", "description": "An intrinsic cardiomyopathy that is characterized by an an enlarged heart and damage to the myocardium causing the heart to pump blood inefficiently." }, "synonyms": [ { "id": "DOID:12930", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12930", "name": "primary dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "Familial dilated cardiomyopathy with conduction defect due to LMNA mutation is a rare familial dilated cardiomyopathy characterized by left ventricular enlargement and/or reduced systolic function preceded or accompanied by significant conduction system disease and/or arrhythmias including bradyarrhythmias, supraventricular or ventricular arrhythmias. Disease onset is usually in early to mid-adulthood. Sudden cardiac death may occur and may be the presenting symptom. In some cases, it is associated with skeletal myopathy and elevated serum creatine kinase." }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "CDCD1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "LMNA familial isolated dilated cardiomyopathy", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy dilated with conduction defect type 1", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "cardiomyopathy, dilated, type 1A", "description": "" }, { "id": "MONDO:0007269", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007269", "name": "dilated cardiomyopathy 1A", "description": "" }, { "id": "MONDO:0007269", "resource": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F6L6-1", "uniprot_ac": "E7F6L6", "uniprot_id": "E7F6L6_DANRE", "mass": { "chemical_mass": 195098.0, "monoisotopic_mass": 195098.0 }, "refseq": { "ac": "XP_005165902", "name": "protein TANC1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165902" }, "gene_names": [ { "name": "tanc1a", "type": "recommended", "evidence": [ { "id": "E7F6L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6L6" } ] }, { "name": "tanc1a", "type": "synonym", "evidence": [ { "id": "XP_005165902", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165902" } ] } ], "protein_names": [ { "name": "Protein TANC1 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F6L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6L6/entry#names_and_taxonomy" } ] }, { "name": "protein TANC1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005165902", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165902" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005165902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165902" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F6L6", "url": "https://www.uniprot.org/uniprotkb/E7F6L6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tanc1a", "url": "https://www.uniprot.org/uniprotkb/E7F6L6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-819", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-819", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077073", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077073", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "561438", "url": "https://www.ncbi.nlm.nih.gov/gene/561438", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050889", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050889", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058018", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058018", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058056", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058056", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561438", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561438", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ECREQMA", "url": "https://omabrowser.org/oma/group/ECREQMA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M1QUT1", "url": "https://www.orthodb.org/?gene=A0A8M1QUT1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BD49", "url": "https://www.orthodb.org/?gene=A0A8M2BD49", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F6L6", "url": "https://www.orthodb.org/?gene=E7F6L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25520", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25520", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25521", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25521", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005165902", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165902", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M1QUT1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1QUT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1QUT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1QUT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BD49", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BD49", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BD49-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BD49-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTQ3", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JTQ3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JTQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F6L6", "url": "https://www.uniprot.org/uniprotkb/E7F6L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F6L6-1", "url": "https://www.uniprot.org/uniprotkb/E7F6L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-819", "url": "https://zfin.org/ZDB-GENE-130530-819", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFKAVLKKGREGGGRASKRDAGSQPLSPSFHQRFEEQGIVGVQDRGSVLLPVQPYPAEEMLRPSLTRGVSVSLPSSPLLPPRQPYLSPVRTNKSPGSIRTPKYVENLCVPGAPVTCSLKNRKKSNTELLSPAESGSSPAVQELMTRLGFLLGDAIPTSSQTNMEDKQCIVSSQGVSPCSTLTSSTASPSAESPCSTLPESSSNSRAPVICSSACSTATSTVITTPSSTLESKDSGIIATVTSSSENEERCGSSLEWAKDGGAGVRGESGRSCIPITPEEPTVSSEVQPRTSSTGGAAPVVTSPLDGPITYHSASLVMPRPNSVAATSSTKLEELRYLDEQRNAPQRSSMRLPWHGAHTGGRSQETKARLTPYKPVDIMLKPLLFEVPSVSMDAVFVGRDWLFQRLEEVLAGGGDADEGKGAVIIGNVGFGKTAVISRLVALSCHGGRMRQIASSSPEATPQNRGSDAAQSSQLNPASQSPIRCPSTPETHRHREGAVKRLAGKVVAYHYCQADNTYTCLVPEFVHSVSALLCRAPLLNAYRELLLRETHLQSLLSLRSCVQDPAAAFRKGVLEPLTLLRKERKIPEEDYIILVDGLNEAEFHKPDYGDTIASFVTKIISKFPVWLKLIVTVRANLVEVTNLLPFPVISLDDFHDNKDITSDLTSYIQQRIDHSPDIISNIAINGKADPANISKLSSHLIARSQGSYLYLKLTLDLFEKGHLVIKSSSYKVIPVSLSELYLLQCNMKFPSASAFERVLPLLNVALASLHPLTDEQLFRALNAGFMTGELEWEDFQQRMDALSCFLISRRDKTRMFCHPSFREWLVWRADGESTDFLCDPRSGHALMAFMLSRQEGKLNRQQTMELGHHILKAHIFKGHSKRTGVSSSVLQPLWISYSTDSLSAALSSLRNLYTPNVKVSRLLILGGASVCYRTEVLNSAPVLCVQSHLGHLEMAALLLESGAPVDGQSENGMTSLCYASAAGHLPLVTLLCKKGAKVDHADKSGQCALVHAALRGHAEILQYLLEQDWSSDLKNKALQQALIAASSMGHTQVVKKMLALNNDEFSVQIDGHDTLWGETALTAAAGRGKQEGCVFLLDQGAIVTQPNRRGVAPIFNAVRHGHTQIAELFLQRGADVNCGDKHGRSLLMVAASEGHLETVDFLLSKGACLTAVDKEGLTPLGWACLKGQKKVVEFLVDRGAQIDHTDKHGRTPLDLAAFYGDADIVHYLVECGAAIEHMDYSGMRPLDRAIGSRNTSVVVTLLKKGAKLGYRTSPYERSGNAAWAMATSKPDILIILLQRLMEEGNLLYKKGKMKEAAQRYQYALRKFPREGFGEDLKAFRELRVSLYLNLSRCRRKTNDFGMAEEFATKALELKPKSYEAFYARARAKRSSRQFAAALADLYEAARLCPSNREIRRLLARVEEECQHLQRQGSKHPTSHGNPSHHEDDNENDDEEDDDEVEDDDQDIESLEKSPDSLSINMLQADDEEERREQESSRQDKRKESWHQSRTLPDSLCLALSDAQSAISTAAPGRVAHRRLPSRQAQSMKNREYSSSLHAEGRTPQSAGSSPMPSRHRPTSLRAGPCIDIGGLDRSPLGDAREGGIQFSLAEKAEINIEPREFCRSSSVRVSSSSSGNLTDTSRLRNSMASAPDRQSEHKPRPFMGVIDKTARFQQQQQQSHHGSLVSSYGWPEGLVGHNVGVVVNTHSQGLTSDLQYSKSSAYQEPIHNSTLTTEFHSGAGYKDTNPLQQHYNDTKHKQASLARDNPILISSIKPKRSFIESNV", "length": 1781, "header": "tr|E7F6L6-1|E7F6L6_DANRE Isoform 1 of Protein TANC1 isoform X1 OS=Danio rerio OX=7955 GN=tanc1a PE=3 SV=2 CANONICAL=E7F6L6-1" }, "isoforms": [ { "isoform_ac": "A0A8M1QUT1-1", "url": "https://www.uniprot.org/uniprotkb/E7F6L6/entry#A0A8M1QUT1-1", "sequence": { "sequence": "MFKAVLKKGREGGGRASKRDAGSQPLSPSFHQRFEEQGIVGVQDRGSVLLPVQPYPAEEMLRPSLTRGVSVSLPSSPLLPPRQPYLSPVRTNKSPGSIRTPKYVENLCVPGAPVTCSLKNRKKSNTELLSPAESGSSPAVQELMTRLGFLLGDAIPTSSQTNMEDKQCIVSSQGVSPCSTLTSSTASPSAESPCSTLPESSSNSRAPVICSSACSTATSTVITTPSSTLESKDSGIIATVTSSSENEERCGSSLEWAKDGGAGVRGESGRSCIPITPEEPTVSSEVQPRTSSTGGAAPVVTSPLDGPITYHSASLVMPRPNSVAATSSTKLEELRYLDEQRNAPQRSSMRLPWHGAHTGGRSQETKARLTPYKPVDIMLKPLLFEVPSVSMDAVFVGRDWLFQRLEEVLAGGGDADEGKGAVIIGNVGFGKTAVISRLVALSCHGGRMRQIASSSPEATPQNRGSDAAQSSQLNPASQSPIRCPSTPETHRHREGAVKRLAGKVVAYHYCQADNTYTCLVPEFVHSVSALLCRAPLLNAYRELLLRETHLQSLLSLRSCVQDPAAAFRKGVLEPLTLLRKERKIPEEDYIILVDGLNEAEFHKPDYGDTIASFVTKIISKFPVWLKLIVTVRANLVEVTNLLPFPVISLDDFHDNKDITSDLTSYIQQRIDHSPDIISNIAINGKADPANISKLSSHLIARSQGSYLYLKLTLDLFEKGHLVIKSSSYKVIPVSLSELYLLQCNMKFPSASAFERVLPLLNVALASLHPLTDEQLFRALNAGFMTGELEWEDFQQRMDALSCFLISRRDKTRMFCHPSFREWLVWRADGESTDFLCDPRSGHALMAFMLSRQEGKLNRQQTMELGHHILKAHIFKGHSKRTGVSSSVLQPLWISYSTDSLSAALSSLRNLYTPNVKVSRLLILGGASVCYRTEVLNSAPVLCVQSHLGHLEMAALLLESGAPVDGQSENGMTSLCYASAAGHLPLVTLLCKKGAKVDHADKSGQCALVHAALRGHAEILQYLLEQDWSSDLKNKALQQALIAASSMGHTQVVKKMLALNNDEFSVQIDGHDTLWGETALTAAAGRGKQEGCVFLLDQGAIVTQPNRRGVAPIFNAVRHGHTQIAELFLQRGADVNCGDKHGRSLLMVAASEGHLETVDFLLSKGACLTAVDKEGLTPLGWACLKGQKKVVEFLVDRGAQIDHTDKHGRTPLDLAAFYGDADIVHYLVECGAAIEHMDYSGMRPLDRAIGSRNTSVVVTLLKKGAKLGNAAWAMATSKPDILIILLQRLMEEGNLLYKKGKMKEAAQRYQYALRKFPREGFGEDLKAFRELRVSLYLNLSRCRRKTNDFGMAEEFATKALELKPKSYEAFYARARAKRSSRQFAAALADLYEAARLCPSNREIRRLLARVEEECQHLQRQGSKHPTSHGNPSHHEDDNENDDEEDDDEVEDDDQDIESLEKSPDSLSINMLQADDEEERREQESSRQDKRKESWHQSRTLPDSLCLALSDAQSAISTAAPGRVAHRRLPSRQAQSMKNREYSSSLHAEGRTPQSAGSSPMPSRHRPTSLRAGPCIDIGGLDRSPLGDAREGGIQFSLAEKAEINIEPREFCRSSSVRVSSSSSGNLTDTSRLRNSMASAPDRQSEHKPRPFMGVIDKTARFQQQQQQSHHGSLVSSYGWPEGLVGHNVGVVVNTHSQGLTSDLQYSKSSAYQEPIHNSTLTTEFHSGAGYKDTNPLQQHYNDTKHKQASLARDNPILISSIKPKRSFIESNV", "length": 1771, "header": "tr|A0A8M1QUT1-1|E7F6L6_DANRE Computationally mapped isoform of Protein TANC1 isoform X1 OS=Danio rerio OX=7955 GN=tanc1a PE=3 SV=1 CANONICAL=E7F6L6-1" }, "locus": {} }, { "isoform_ac": "A0A8M2BD49-1", "url": "https://www.uniprot.org/uniprotkb/E7F6L6/entry#A0A8M2BD49-1", "sequence": { "sequence": "MTRLGFLLGDAIPTSSQTNMEDKQCIVSSQGVSPCSTLTSSTASPSAESPCSTLPESSSNSRAPVICSSACSTATSTVITTPSSTLESKDSGIIATVTSSSENEERCGSSLEWAKDGGAGVRGESGRSCIPITPEEPTVSSEVQPRTSSTGGAAPVVTSPLDGPITYHSASLVMPRPNSVAATSSTKLEELRYLDEQRNAPQRSSMRLPWHGAHTGGRSQETKARLTPYKPVDIMLKPLLFEVPSVSMDAVFVGRDWLFQRLEEVLAGGGDADEGKGAVIIGNVGFGKTAVISRLVALSCHGGRMRQIASSSPEATPQNRGSDAAQSSQLNPASQSPIRCPSTPETHRHREGAVKRLAGKVVAYHYCQADNTYTCLVPEFVHSVSALLCRAPLLNAYRELLLRETHLQSLLSLRSCVQDPAAAFRKGVLEPLTLLRKERKIPEEDYIILVDGLNEAEFHKPDYGDTIASFVTKIISKFPVWLKLIVTVRANLVEVTNLLPFPVISLDDFHDNKDITSDLTSYIQQRIDHSPDIISNIAINGKADPANISKLSSHLIARSQGSYLYLKLTLDLFEKGHLVIKSSSYKVIPVSLSELYLLQCNMKFPSASAFERVLPLLNVALASLHPLTDEQLFRALNAGFMTGELEWEDFQQRMDALSCFLISRRDKTRMFCHPSFREWLVWRADGESTDFLCDPRSGHALMAFMLSRQEGKLNRQQTMELGHHILKAHIFKGHSKRTGVSSSVLQPLWISYSTDSLSAALSSLRNLYTPNVKVSRLLILGGASVCYRTEVLNSAPVLCVQSHLGHLEMAALLLESGAPVDGQSENGMTSLCYASAAGHLPLVTLLCKKGAKVDHADKSGQCALVHAALRGHAEILQYLLEQDWSSDLKNKALQQALIAASSMGHTQVVKKMLALNNDEFSVQIDGHDTLWGETALTAAAGRGKQEGCVFLLDQGAIVTQPNRRGVAPIFNAVRHGHTQIAELFLQRGADVNCGDKHGRSLLMVAASEGHLETVDFLLSKGACLTAVDKEGLTPLGWACLKGQKKVVEFLVDRGAQIDHTDKHGRTPLDLAAFYGDADIVHYLVECGAAIEHMDYSGMRPLDRAIGSRNTSVVVTLLKKGAKLGYRTSPYERSGNAAWAMATSKPDILIILLQRLMEEGNLLYKKGKMKEAAQRYQYALRKFPREGFGEDLKAFRELRVSLYLNLSRCRRKTNDFGMAEEFATKALELKPKSYEAFYARARAKRSSRQFAAALADLYEAARLCPSNREIRRLLARVEEECQHLQRQGSKHPTSHGNPSHHEDDNENDDEEDDDEVEDDDQDIESLEKSPDSLSINMLQADDEEERREQESSRQDKRKESWHQSRTLPDSLCLALSDAQSAISTAAPGRVAHRRLPSRQAQSMKNREYSSSLHAEGRTPQSAGSSPMPSRHRPTSLRAGPCIDIGGLDRSPLGDAREGGIQFSLAEKAEINIEPREFCRSSSVRVSSSSSGNLTDTSRLRNSMASAPDRQSEHKPRPFMGVIDKTARFQQQQQQSHHGSLVSSYGWPEGLVGHNVGVVVNTHSQGLTSDLQYSKSSAYQEPIHNSTLTTEFHSGAGYKDTNPLQQHYNDTKHKQASLARDNPILISSIKPKRSFIESNV", "length": 1638, "header": "tr|A0A8M2BD49-1|E7F6L6_DANRE Computationally mapped isoform of Protein TANC1 isoform X1 OS=Danio rerio OX=7955 GN=tanc1a PE=3 SV=1 CANONICAL=E7F6L6-1" }, "locus": {} }, { "isoform_ac": "A0AC58JTQ3-1", "url": "https://www.uniprot.org/uniprotkb/E7F6L6/entry#A0AC58JTQ3-1", "sequence": { "sequence": "MTRLGFLLGDAIPTSSQTNMEDKQCIVSSQGVSPCSTLTSSTASPSAESPCSTLPESSSNSRAPVICSSACSTATSTVITTPSSTLESKDSGIIATVTSSSENEERCGSSLEWAKDGGAGVRGESGRSCIPITPEEPTVSSEVQPRTSSTGGAAPVVTSPLDGPITYHSASLVMPRPNSVAATSSTKLEELRYLDEQRNAPQRSSMRLPWHGAHTGGRSQETKARLTPYKPVDIMLKPLLFEVPSVSMDAVFVGRDWLFQRLEEVLAGGGDADEGKGAVIIGNVGFGKTAVISRLVALSCHGGRMRQIASSSPEATPQNRGSDAAQSSQLNPASQSPIRCPSTPETHRHREGAVKRLAGKVVAYHYCQADNTYTCLVPEFVHSVSALLCRAPLLNAYRELLLRETHLQSLLSLRSCVQDPAAAFRKGVLEPLTLLRKERKIPEEDYIILVDGLNEAEFHKPDYGDTIASFVTKIISKFPVWLKLIVTVRANLVEVTNLLPFPVISLDDFHDNKDITSDLTSYIQQRIDHSPDIISNIAINGKADPANISKLSSHLIARSQGSYLYLKLTLDLFEKGHLVIKSSSYKVIPVSLSELYLLQCNMKFPSASAFERVLPLLNVALASLHPLTDEQLFRALNAGFMTGELEWEDFQQRMDALSCFLISRRDKTRMFCHPSFREWLVWRADGESTDFLCDPRSGHALMAFMLSRQEGKLNRQQTMELGHHILKAHIFKGHSKRTGVSSSVLQPLWISYSTDSLSAALSSLRNLYTPNVKVSRLLILGGASVCYRTEVLNSAPVLCVQSHLGHLEMAALLLESGAPVDGQSENGMTSLCYASAAGHLPLVTLLCKKGAKVDHADKSGQCALVHAALRGHAEILQYLLEQDWSSDLKNKALQQALIAASSMGHTQVVKKMLALNNDEFSVQIDGHDTLWGETALTAAAGRGKQEGCVFLLDQGAIVTQPNRRGVAPIFNAVRHGHTQIAELFLQRGADVNCGDKHGRSLLMVAASEGHLETVDFLLSKGACLTAVDKEGLTPLGWACLKGQKKVVEFLVDRGAQIDHTDKHGRTPLDLAAFYGDADIVHYLVECGAAIEHMDYSGMRPLDRAIGSRNTSVVVTLLKKGAKLGNAAWAMATSKPDILIILLQRLMEEGNLLYKKGKMKEAAQRYQYALRKFPREGFGEDLKAFRELRVSLYLNLSRCRRKTNDFGMAEEFATKALELKPKSYEAFYARARAKRSSRQFAAALADLYEAARLCPSNREIRRLLARVEEECQHLQRQGSKHPTSHGNPSHHEDDNENDDEEDDDEVEDDDQDIESLEKSPDSLSINMLQADDEEERREQESSRQDKRKESWHQSRTLPDSLCLALSDAQSAISTAAPGRVAHRRLPSRQAQSMKNREYSSSLHAEGRTPQSAGSSPMPSRHRPTSLRAGPCIDIGGLDRSPLGDAREGGIQFSLAEKAEINIEPREFCRSSSVRVSSSSSGNLTDTSRLRNSMASAPDRQSEHKPRPFMGVIDKTARFQQQQQQSHHGSLVSSYGWPEGLVGHNVGVVVNTHSQGLTSDLQYSKSSAYQEPIHNSTLTTEFHSGAGYKDTNPLQQHYNDTKHKQASLARDNPILISSIKPKRSFIESNV", "length": 1628, "header": "tr|A0AC58JTQ3-1|A0AC58JTQ3_DANRE Computationally mapped isoform of Protein TANC1 isoform X4 OS=Danio rerio OX=7955 GN=tanc1a PE=3 SV=1 CANONICAL=E7F6L6-1" }, "locus": {} }, { "isoform_ac": "E7F6L6-1", "url": "https://www.uniprot.org/uniprotkb/E7F6L6/entry#E7F6L6-1", "sequence": { "sequence": "MFKAVLKKGREGGGRASKRDAGSQPLSPSFHQRFEEQGIVGVQDRGSVLLPVQPYPAEEMLRPSLTRGVSVSLPSSPLLPPRQPYLSPVRTNKSPGSIRTPKYVENLCVPGAPVTCSLKNRKKSNTELLSPAESGSSPAVQELMTRLGFLLGDAIPTSSQTNMEDKQCIVSSQGVSPCSTLTSSTASPSAESPCSTLPESSSNSRAPVICSSACSTATSTVITTPSSTLESKDSGIIATVTSSSENEERCGSSLEWAKDGGAGVRGESGRSCIPITPEEPTVSSEVQPRTSSTGGAAPVVTSPLDGPITYHSASLVMPRPNSVAATSSTKLEELRYLDEQRNAPQRSSMRLPWHGAHTGGRSQETKARLTPYKPVDIMLKPLLFEVPSVSMDAVFVGRDWLFQRLEEVLAGGGDADEGKGAVIIGNVGFGKTAVISRLVALSCHGGRMRQIASSSPEATPQNRGSDAAQSSQLNPASQSPIRCPSTPETHRHREGAVKRLAGKVVAYHYCQADNTYTCLVPEFVHSVSALLCRAPLLNAYRELLLRETHLQSLLSLRSCVQDPAAAFRKGVLEPLTLLRKERKIPEEDYIILVDGLNEAEFHKPDYGDTIASFVTKIISKFPVWLKLIVTVRANLVEVTNLLPFPVISLDDFHDNKDITSDLTSYIQQRIDHSPDIISNIAINGKADPANISKLSSHLIARSQGSYLYLKLTLDLFEKGHLVIKSSSYKVIPVSLSELYLLQCNMKFPSASAFERVLPLLNVALASLHPLTDEQLFRALNAGFMTGELEWEDFQQRMDALSCFLISRRDKTRMFCHPSFREWLVWRADGESTDFLCDPRSGHALMAFMLSRQEGKLNRQQTMELGHHILKAHIFKGHSKRTGVSSSVLQPLWISYSTDSLSAALSSLRNLYTPNVKVSRLLILGGASVCYRTEVLNSAPVLCVQSHLGHLEMAALLLESGAPVDGQSENGMTSLCYASAAGHLPLVTLLCKKGAKVDHADKSGQCALVHAALRGHAEILQYLLEQDWSSDLKNKALQQALIAASSMGHTQVVKKMLALNNDEFSVQIDGHDTLWGETALTAAAGRGKQEGCVFLLDQGAIVTQPNRRGVAPIFNAVRHGHTQIAELFLQRGADVNCGDKHGRSLLMVAASEGHLETVDFLLSKGACLTAVDKEGLTPLGWACLKGQKKVVEFLVDRGAQIDHTDKHGRTPLDLAAFYGDADIVHYLVECGAAIEHMDYSGMRPLDRAIGSRNTSVVVTLLKKGAKLGYRTSPYERSGNAAWAMATSKPDILIILLQRLMEEGNLLYKKGKMKEAAQRYQYALRKFPREGFGEDLKAFRELRVSLYLNLSRCRRKTNDFGMAEEFATKALELKPKSYEAFYARARAKRSSRQFAAALADLYEAARLCPSNREIRRLLARVEEECQHLQRQGSKHPTSHGNPSHHEDDNENDDEEDDDEVEDDDQDIESLEKSPDSLSINMLQADDEEERREQESSRQDKRKESWHQSRTLPDSLCLALSDAQSAISTAAPGRVAHRRLPSRQAQSMKNREYSSSLHAEGRTPQSAGSSPMPSRHRPTSLRAGPCIDIGGLDRSPLGDAREGGIQFSLAEKAEINIEPREFCRSSSVRVSSSSSGNLTDTSRLRNSMASAPDRQSEHKPRPFMGVIDKTARFQQQQQQSHHGSLVSSYGWPEGLVGHNVGVVVNTHSQGLTSDLQYSKSSAYQEPIHNSTLTTEFHSGAGYKDTNPLQQHYNDTKHKQASLARDNPILISSIKPKRSFIESNV", "length": 1781, "header": "tr|E7F6L6-1|E7F6L6_DANRE Isoform 1 of Protein TANC1 isoform X1 OS=Danio rerio OX=7955 GN=tanc1a PE=3 SV=2 CANONICAL=E7F6L6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561438", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561438", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32TVH4-1", "protein_name": "Protein TANC1 isoform X1", "gene_name": "tanc1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTSEGGGGAARASSSAHRLSVREKRRPQTFPRRRINDINQSSHSWSHAMFKAVLKKSRDGGKNKKDAGEPLVLSGQWRCAGGGMPDPYPSADEGLRLGFSKGVSMSLPSSPLLPRHTYVMAARPCKKSPGLVRKPKYVESPRIPGDVCAASLKKVPDSATAGSSSSTQELMTRLGFLLGEGIPGSTHIPMDGKNDKKCPVNQGISPCSTLTSSTASPSTDSPCSTLNSSGRPGLTAVCITSPSSTLDSKDSGIIATITSSSENEERSGSSLEWSKEGSIRSCGQHVLGQTATRTDTCSPVAEEEPSASGTGLRIVPNTKKNSEGPVQYTTQNPSSLMMPRPNSVAATSSTKLEDLSFLDEQRNTPLRTSIRLPWHNTGGRAPHDKACFAPYKPTDIMLKPLLFEVPSITTDSVFVGRDWLFQQLEDDLSPSQSGESSSSGSILVGNVGFGKTAIISRLVALSCHGGRMRQIASNSPTASPKSAEVSSDVPLSQSTPPLSTSSTLSSSSCPNTPELQRHRDQAVRRLAAKVVAYHYCQADNTYTCLVPEFVHSVSALLCRAHQLTAYRDLLLKETHLQSVLSLRSCVQDPSAAFRRGILQPLINLRKERKIPEEDCIILVDGLNEAEFHKPDYGDTVASFITKIIPKFPSWLKLIVTVRTNLLEITSLMPFSKISLDDFPDNQEIGTDLNAYIQQRISGSSNILSNISLNGKSDPVIVSKVSSHLISRSQGSYLYLKLTLDLFERGHLVIKSASYKVVPVSLSELYLLQCNMKFLSNSAFERAVPVLNVALASLHPLTDEQLFQALNAGSQRGELEWDDFQQRMETLSCFLIRRRDKTRMFCHPSFREWLVWRADGESSDFLCDPRSGHALMAFMLSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGVSSSVLQALWISCSTDGLSAALASLRNLYTPNVKVSRLLMLGGANVNYRTEVLNNGPVLCVQSHLGHQEMVALLLEFGANVDVLSENGMSALCYAAAAGHLELISLLCKRGAKVDHVDKSGQCALVHAALRGHSEVIECLLELHWSSESQQEHSLKSRALQQALIAACSMGHIHVLEGLLAMNDELSVQIDAHDTLWGETALTAAAGRGKMEVCSFLLKREAQVQQVNRRGACALFCAVRQGHWQIADLLLQHGADVNVSDKQGRTLLMVAACEGHLSTADFLLSKGASVASVDKEGLTPLSWACLKGHKSVVQFLVEKGAVIDHSDKNGRSPLDLAAFYGDADIVHYLVEKGAVIEHVDYSGMRPLDRAIGCRNTSVVLTLLKKGAKLGNAAWAMATSKPDILIILLQKLMEEGNLLYKRGKMKEAAQRYQYALRKFPREGFGDELKAFKELRVSLYLNLSRCRRKTNDFGLAEDFATKALELKPKSYEAYYARARAKRSSRQFTAALADLHEASKLCPNNREICRLLARVEDECKQMQRSQSKQQNLSNPEHHQQEHAEEEEDDDDEDDSEAWSQNIYSLNRTSNGRSASPPHKHSLRQQHKSLLLQPSKQAQIVKTNQHLGSLQPASGRGKNQYAPSSPIPSRHISSVLKAGPGIDISPLAPANAVETEDLHHVQVHSTLDGANVNASQDLRKDANASMRVSSSTSSLASSSSLSDSGKTQGPDVRTKTRTDKGKISQSGSVDYKPRPFMGVMDKTARFQQPTATRSWQSHSTDGVVASAGEITFAKPSSVYYEQMKGPAGLHNGGLHAKEFGHKEGKAVLAHSFTDSKPGLNRETATAHVASMKPKRSFIESNV", "length": 1766 }, "evidence": [ { "id": "HGNC:29364", "url": "https://alliancegenome.org/gene/HGNC:29364#orthology", "database": "AGR" }, { "id": "MGI:1914110", "url": "https://alliancegenome.org/gene/MGI:1914110#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q0VGY8-1", "protein_name": "Protein TANC1", "gene_name": "Tanc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLKAVLKKSREGGKGSKKEAGGDFGSETPALSSSGDSPVNSLSTTEDTYRVSLAKGVSMSLPSSPLLPRQSLLTQSRSNKKSPGPVRKPKYVESPRVPGDPVMIPFGEGSKPSEPSATEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNEAMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAASKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNRDGSLRLGVQKGVLHDRRADNCSPVAEEETTGSAESVLPKAEPSAGDGPVPYPQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRAPEVKARFAPYKPQEILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELAENRGAVVVGSVGFGKTAIISKLVALSCHGSRMRQIASSSPSLSPKSSDPTQDLPGTPLLSPSSSTSALSVTRTPAGPGTADSQRPREDAVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTSLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIIPKFPTWLKLIVTVRANFQEIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALISKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFDRALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQRMEALSCFLIKRRDKTRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTMELGHHILKAHIFKGLSKKTGVSSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMKLVCLLIKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQALQQALTAAASMGHSSVVQSLLGMAEEHEIEVNGTDTLWGETALTAAAGRGKVEICELLLERGAAVSRANRRGVPPLFCAARQGHWQVVRLLLDRGCDVNLSDKQGRTPLMVASCEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLGNAAWAMATSKPDILIILLQKLVEEGNVMYKKGKMKEAAQRYQYALRKFPREGLGEDMRPFNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLAALADLQEAVKLCPNNQEIKRLLARVEEECKQLQRNQQQKQQGPPPAPANDSDNEEDAPASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRSASPQSRAGISKSLRETVAQSGLVMQPTKQAQIVKTNQHLGSGQSSMRNSSTKIQVSSQNPPPSPMPGRVSAAPAVSRNQHLEGTGPFTAGTGCGHFGDRLGASQSLQLQRSESGTAYPLPSKVKAAERLLAHASVAVDMAPPNQGGPVSCSDVRHPASLSSSGSSGSPSSSIKMSSSTSSLTSSSSVSDGFKVQGPDSRIRDKGTTQVQGGTAEHRPRNTPFMGIMDKTARFQQQSNPPNRSWHCPVAEGLLTNTATAAGLQSNSEKPTLKPGGYCSQAKPCSVPPLSMGVHNGAQVKELEENKCQIPALCQDNRITKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKRSFIESNV", "length": 1856 }, "evidence": [ { "id": "HGNC:29364", "url": "https://alliancegenome.org/gene/HGNC:29364#orthology", "database": "AGR" }, { "id": "MGI:1914110", "url": "https://alliancegenome.org/gene/MGI:1914110#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-819", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-819#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6F6B3-1", "protein_name": "Protein TANC1", "gene_name": "Tanc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLKAVLKKSREGVKGSKKEAGGDFGSETPTLSSSGDSPVNSLSTTEDTYRVSLAKGVSMSLPSSPLLPRQSHLTQSRANKKSPGPVRKPKYVESPRVPGDPVMIPFREGSKPAEPIETEAKVDNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNEAMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNRDGSLRLGVQKGVLHDRRLDNCSPVAEEETTGSAESVLPKAESSAGDGPVPYSQSSGSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHSTAGARFAPYKPQEILLKPLLFEVPSITTDSVFVGRDWLFQQIEENLRNTELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQVASSSPSSSLKTSDPTHDLPGTPLLSPSSSTSALSAARTPPGPGTVDSQRPREDAVKYLASRVVAYHYCQADNTYTCLVPEFVHSIATLLCRSHQLAAYRDLLIREPQLQSMLNLRSCVQDPVAAFKRGILEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDHGDTLSSFITKIIPKFPPWLKLIVTVRADFQEIISTLPFVKLSLDDFPGNQDIHSDLHAYVQHRVHSSQDILSNISLNGKADAALIGKVSSRLVLRNLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFDRALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQKMEALSCFLIKKRDKTRMFCHPSFREWLVWRADGESTAFLCEPRNGHALLAFMFSRQESKLNRQQTVELGHHILKAHIFKGLSKKTGVSSSHPQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGMSENGMNALCYAAAAGHMKLVCLLTKKGARVDHLDKKGQCALVHSALRGHSDILQYLLNCEWSAGPPQPGTLRKSQALQQALTAAASMGHSAVVQSLLGMAEEHEIEVNGTDTLWGETALTAAAGRGKLEICELLLERGAAVSRANRRGVPPLFCAARQGHWQVVQLLLDRGCDVNPNDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAEIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTAVVVTLLRKGAKLGNAAWAMATFKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGPGEDMRPFNELRVSLYLNLSRCRRKTNDFGLAEEFASKALELKPKSYEAFYARARAKRNSRQFLAALADLQEAVKLCPTNQEIKRLLARVEEECKQLQRNQQQKQQAPLPAPPNDSDNDEEAPASSLKDHFPIEEAEEEDTSSQEESISPTPRSQPPPSVPSPYIRNLQEGLQSKGRPASPQSWAGISKSLRETVAQPGLVMQPTKQAQIVKTNQHLGSGQSSMRNSNTKVQVSSQNPPPSPMPGRVSAAPAVSRNQHLEGTGPFSTGTGCGHFGDRLGPSQSLQLQRGESGTAYPLPSKVKAAERLLAHASVAVDMALPSQGGPVSCSDVRHPASLSSSGSSGSPSSSVKMSSSTSSLTSSSSVSDGFKAQGPDCRIRDRGTTQVQGGTAEHRPRNTPFMGIMDKIARFQQQVNPPSRSWHCPVTEGLLTNTATAAGLQTNSEKPALKPGGYCSQAKPCSVPPLGMGVHNGAQVKELEENKCQVPALCQDNRKTKGVPHLYPEGVSKQPLHVSTEAHRSHLTSAKPKRSFIESNV", "length": 1849 }, "evidence": [ { "id": "HGNC:29364", "url": "https://alliancegenome.org/gene/HGNC:29364#orthology", "database": "AGR" }, { "id": "MGI:1914110", "url": "https://alliancegenome.org/gene/MGI:1914110#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9C0D5-1", "protein_name": "Protein TANC1", "gene_name": "TANC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLKAVLKKSREGGKGGKKEAGSDFGPETSPVLHLDHSADSPVSSLPTAEDTYRVSLAKGVSMSLPSSPLLPRQSHLVQSRVNKKSPGPVRKPKYVESPRVPGDAVIMPFREVAKPTEPDEHEAKADNEPSCSPAAQELLTRLGFLLGEGIPSATHITIEDKNETMCTALSQGISPCSTLTSSTASPSTDSPCSTLNSCVSKTAANKSPCETISSPSSTLESKDSGIIATITSSSENDDRSGSSLEWNKDGNLRLGVQKGVLHDRRADNCSPVAEEETTGSAESTLPKAESSAGDGPVPYSQGSSSLIMPRPNSVAATSSTKLEDLSYLDGQRNAPLRTSIRLPWHNTAGGRAQEVKARFAPYKPQDILLKPLLFEVPSITTDSVFVGRDWLFHQIEENLRNTELAENRGAVVVGNVGFGKTAIISKLVALSCHGSRMRQIASNSPGSSPKTSDPTQDLHFTPLLSPSSSTSASSTAKTPLGSISAENQRPREDAVKYLASKVVAYHYCQADNTYTCLVPEFVHSIAALLCRSHQLAAYRDLLIKEPQLQSMLSLRSCVQDPVAAFKRGVLEPLTNLRNEQKIPEEEYIILIDGLNEAEFHKPDYGDTLSSFITKIISKFPAWLKLIVTVRANFQEIISALPFVKLSLDDFPDNKDIHSDLHAYVQHRVHSSQDILSNISLNGKADATLIGKVSSHLVLRSLGSYLYLKLTLDLFQRGHLVIKSASYKVVPVSLSELYLLQCNMKFMTQSAFERALPILNVALASLHPMTDEQIFQAINAGHIQGEQGWEDFQQRMDALSCFLIKRRDKTRMFCHPSFREWLVWRADGENTAFLCEPRNGHALLAFMFSRQEGKLNRQQTMELGHHILKAHIFKGLSKKTGISSSHLQALWIGYSTEGLSAALASLRNLYTPNVKVSRLLILGGANVNYRTEVLNNAPILCVQSHLGHEEVVTLLLEFGACLDGTSENGMTALCYAAAAGHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCEWSPGPPQPGTLRKSHALQQALTAAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALTAAAGRGKLEVCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAACEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQYLVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVALLRKGAKLGNAAWAMATSKPDILIILLQKLMEEGNVMYKKGKMKEAAQRYQYALRKFPREGFGEDMRPFNELRVSLYLNLSRCRRKTNDFGMAEEFASKALELKPKSYEAFYARARAKRNSRQFVAALADLQEAVKLCPTNQEVKRLLARVEEECKQLQRSQQQKQQGPLPAPLNDSENEEDTPTPGLSDHFHSEETEEEETSPQEESVSPTPRSQPSSSVPSSYIRNLQEGLQSKGRPVSPQSRAGIGKSLREPVAQPGLLLQPSKQAQIVKTSQHLGSGQSAVRNGSMKVQISSQNPPPSPMPGRIAATPAGSRTQHLEGTGTFTTRAGCGHFGDRLGPSQNVRLQCGENGPAHPLPSKTKTTERLLSHSSVAVDAAPPNQGGLATCSDVRHPASLTSSGSSGSPSSSIKMSSSTSSLTSSSSFSDGFKVQGPDTRIKDKVVTHVQSGTAEHRPRNTPFMGIMDKTARFQQQSNPPSRSWHCPAPEGLLTNTSSAAGLQSANTEKPSLMQVGGYNNQAKTCSVSTLSASVHNGAQVKELEESKCQIPVHSQENRITKTVSHLYQESISKQQPHISNEAHRSHLTAAKPKRSFIESNV", "length": 1861 }, "evidence": [ { "id": "HGNC:29364", "url": "https://alliancegenome.org/gene/HGNC:29364#orthology", "database": "AGR" }, { "id": "MGI:1914110", "url": "https://alliancegenome.org/gene/MGI:1914110#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-819", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-819#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VTS9-1", "protein_name": "Rolling pebbles, isoform B", "gene_name": "rols", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPSLQQIALAMEGDQSELQTPPLPINPPPKVMANGIVYGFRTRHLSCIEENDSDSLHGSSIPHAYDMMQQADETFQKLNANEEQDESGSEDGGLENLDDTIAMIDESRLLEADYLDELVAEEQLQEQDEDEEESSDLVDSGNVEEDFWQPSFNRNDIMMTSVYGALNGSLTSEVSSTAAPGYSECATPRKEAEPVYATPEKRRASNRSFDSTCASLTSSLYGGSMNSSLDLKYSSLGGGDSVSGGISGTSTLRGTSVPPMDLSMISSDGVSALDWGSASVSCVLDSGDGNPAEELNEEMAAKCLSAAESDLQSIRRLLEHDASGSVCPSCRISFDKGKRRKLIDTCGHERCYSCMFRNDQCPMCMNSSLKDVDGANAQGYDTGIGGSTSTIVSPLGSPQPQLRSHAQRNAALARYMQQHRQESQSPDYHHRYASNGKLPRAAALSTNGNGFTTGTTQTVTVDVHHQLGGGGGGAAAAAKQLMANGISGHSRSSSMSHNIHAAAYSELSAAPPAFATPPTRRRFFNHKNLRSALTGGSGGGSGVGGGVGGAGGVGGGHRRTASNGGCPIDTASILSGDHTHQHHHRDNQPEGKESNALNTSTCSDSAVTRRRRKNVSNHNLKTSARHGASSENRLNRLSLAGTSVYAGHLSSLVFGKIKSLWSVNSSNSSEAGLNQLAGSDAIDHHSSFLNEKLQKDQLHARLGLLLNDPGSNGNSSSSGSGCEPISAHSTTSTTSSSGVGAASTTTSGSSQNVSPEQTLASGAGMLSGSQLSVATSHGVKEDALSLCGKFKAGCSMLHVYEALPSKSRKGNVRRSTRGQQGSSSSASAASAVGSRVTASSLAAVQLALKPLFFEVPLQEPDPPYVGRQWLVQQLSNILLGTETRVVLINGQPGTGKTAFCLQLVEYSCFGRRQMQDDPDGIYSQLQLGAHCERMRGLASHMVGYHFCQADANLTCQVPDFVHSLAAQLCQAPQLTAYRDYLLSEPHLQDILSVRECIADAERVMKLAILEPLAHLHRAGKIPAKVAVIVVDALCEAEYHRPDHGHTIASFLAQLTPHFPAWLKLVATVRTQMLELVKAPSYTQLTLDSWASSQALQQDMLDYIGARLADSPEIRMNIGGGGGQNSQSGSQPQTKFVSHLQSLSRGSMLYAKLILDLIARGQLVIKSSSYKVLPVSLAQIFLLHFNLRFPTARSFEQAAPILNICLAALYPLTLDEIYYSMEALSHGREALSWPDFMQRFKLLDGFLIKRLDNTYMFFHSSLREWLMRRDEGESNKFLCDARLGHAGIAFRLSRLQAPLSPQLTLELGHHMLKAHLYGGTSLTLLSPRDLQSYWLAGAADNISSSLGALRNVYSPNLKVSRLVLLAGASPNHRTDYMGGAPILCIAAHEGILPMVSLLLEFGADVGLTNSQGCTPLILAAMRGHCDVVRPLVAAGSSLGQLDITQRCALVHAARMGHLSVVKYLLACDWSPRPHSQDVTRSVALQQALIGAAAQAHCKILEDLLDLNETEFDLDVNGMEPSSGELALTAAARHGCIDVVGILLSRGAQIDARNRQGYSALWLAVKEGHWSVVEHLLQRGALLDEPLGQTRKTPLMIAAEEGHLELVDLLLARGAQREAQDHEGFTALSWACLRGHLAAAKTLIEHGCNRHHEDHNGRTALDLAAYQGAASLVIYILEQGGNLEHIDVHGMRPLDRAIACRNIQAVQVFLRKGAKLGPTTWSMAMGKPEILVILLNKLLEDGNVLYRKNRFQEAAHRYQYALRKISGLEQLLERNAIFAQLRTNLLLNLSRCKRKLNELDASIDLATQAIAQKPHSYEGYYARAKARMELGALNEALVDANEAMQQAAQSGVLCEVVEVLKRIQTELLTRISISSEDQTGRMSNIGGGASVAYESHHEITDL", "length": 1900 }, "evidence": [ { "id": "HGNC:29364", "url": "https://alliancegenome.org/gene/HGNC:29364#orthology", "database": "AGR" }, { "id": "MGI:1914110", "url": "https://alliancegenome.org/gene/MGI:1914110#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "postsynapse", "id": "GO:0098794", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098794", "evidence": [ { "database": "UniProtKB", "id": "E7F6L6", "url": "https://www.uniprot.org/uniprotkb/E7F6L6" } ], "pmid": "" }, { "name": "glutamatergic synapse", "id": "GO:0098978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098978", "evidence": [ { "database": "UniProtKB", "id": "E7F6L6", "url": "https://www.uniprot.org/uniprotkb/E7F6L6" } ], "pmid": "" }, { "name": "postsynaptic density, intracellular component", "id": "GO:0099092", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099092", "evidence": [ { "database": "UniProtKB", "id": "E7F6L6", "url": "https://www.uniprot.org/uniprotkb/E7F6L6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of postsynapse organization", "id": "GO:0099175", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0099175", "evidence": [ { "database": "UniProtKB", "id": "E7F6L6", "url": "https://www.uniprot.org/uniprotkb/E7F6L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1252, "end_pos": 1254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1347, "end_pos": 1349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1634, "end_pos": 1636, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1726, "end_pos": 1728, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1750, "end_pos": 1752, "annotation": "n_glycosylation_sequon" }, { "start_pos": 690, "end_pos": 692, "annotation": "n_glycosylation_sequon" }, { "start_pos": 92, "end_pos": 94, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F6L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6L6" }, { "id": "PF25520", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25520" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TANC1/2-like AAA+ ATPase lid", "eco_id": "ECO_0000259", "start_pos": 649, "end_pos": 744, "start_aa": "Leu", "end_aa": "Asn", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7F6L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6L6" }, { "id": "PF25521", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25521" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TANC1/2-like winged helix", "eco_id": "ECO_0000259", "start_pos": 746, "end_pos": 899, "start_aa": "Lys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1252, "end_pos": 1254 }, { "start_pos": 1347, "end_pos": 1349 }, { "start_pos": 1634, "end_pos": 1636 }, { "start_pos": 1726, "end_pos": 1728 }, { "start_pos": 1750, "end_pos": 1752 }, { "start_pos": 690, "end_pos": 692 }, { "start_pos": 92, "end_pos": 94 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FD23-1", "uniprot_ac": "E7FD23", "uniprot_id": "E7FD23_DANRE", "mass": { "chemical_mass": 23805.0, "monoisotopic_mass": 23805.0 }, "refseq": { "ac": "NP_001313477", "name": "uncharacterized protein C7orf57 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313477" }, "gene_names": [ { "name": "si:dkey-276j7.1", "type": "recommended", "evidence": [ { "id": "E7FD23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FD23" } ] }, { "name": "si:dkey-276j7.1", "type": "synonym", "evidence": [ { "id": "NP_001313477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313477" } ] }, { "name": "wu:fq41a10", "type": "synonym", "evidence": [ { "id": "NP_001313477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313477" }, { "id": "E7FD23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FD23" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C7orf57 homolog", "type": "synonym", "evidence": [ { "id": "E7FD23", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FD23/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein C7orf57 homolog", "type": "synonym", "evidence": [ { "id": "NP_001313477", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313477" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH457050.1, EH451046.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505372 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1, EH457050.1 and EH461268.1. On May 20, 2016 this sequence version replaced XP_690269.4.", "evidence": [ { "database": "RefSeq", "id": "NP_001313477", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313477" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FD23", "url": "https://www.uniprot.org/uniprotkb/E7FD23" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-276j7.1", "url": "https://www.uniprot.org/uniprotkb/E7FD23", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060720-44", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060720-44", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000090872", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000090872", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "561769", "url": "https://www.ncbi.nlm.nih.gov/gene/561769", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040247", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040247", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561769", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561769", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KTHWERE", "url": "https://omabrowser.org/oma/group/KTHWERE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BDC3", "url": "https://www.orthodb.org/?gene=A0A8M2BDC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FD23", "url": "https://www.orthodb.org/?gene=E7FD23", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31097", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31097", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31097:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31097:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001313477", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313477", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BDC3", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BDC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BDC3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BDC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FD23", "url": "https://www.uniprot.org/uniprotkb/E7FD23", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FD23-1", "url": "https://www.uniprot.org/uniprotkb/E7FD23-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060720-44", "url": "https://zfin.org/ZDB-GENE-060720-44", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAAEPNYRRTKPGVKQAQNASSNGAVGPSSQIPGLSATAETTPEERTKGRRVGIQASDSDYVKLAKQGGQRGLLWHDDPVEPITNSSYKPSNWFSGSPDDNRSKATSPDGMSKSESKGALQRLEPPFGTDNGSAWDSDKDKNVSYTAAEMEKLSLSQKDIDEANKFKKISHDKKEAAPVNMSKLLSFGYAQDENKSPNDDDASSMTSEQTSTIAPEDELE", "length": 220, "header": "tr|E7FD23-1|E7FD23_DANRE Isoform 1 of Uncharacterized protein C7orf57 homolog OS=Danio rerio OX=7955 GN=si:dkey-276j7.1 PE=1 SV=1 CANONICAL=E7FD23-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BDC3-1", "url": "https://www.uniprot.org/uniprotkb/E7FD23/entry#A0A8M2BDC3-1", "sequence": { "sequence": "MAAEPNYRRTKPGVKQAQNASSNGAVGPSSQIPGLSATAETTPEERTKGRRVGIQASDSDYVKLAKQGGQRGLLWHDDPVEPITNSSYKPSNWFSGSPDDKSKATSPDGMSKSESKGALQRLEPPFGTDNGSAWDSDKDKNVSYTAAEMEKLSLSQKDIDEANKFKKISHDKKEAAPVNMSKLLSFGYAQDENKSPNDDDASSMTSEQTSTIAPEDELE", "length": 219, "header": "tr|A0A8M2BDC3-1|E7FD23_DANRE Computationally mapped isoform of Uncharacterized protein C7orf57 homolog OS=Danio rerio OX=7955 GN=si:dkey-276j7.1 PE=1 SV=1 CANONICAL=E7FD23-1" }, "locus": {} }, { "isoform_ac": "E7FD23-1", "url": "https://www.uniprot.org/uniprotkb/E7FD23/entry#E7FD23-1", "sequence": { "sequence": "MAAEPNYRRTKPGVKQAQNASSNGAVGPSSQIPGLSATAETTPEERTKGRRVGIQASDSDYVKLAKQGGQRGLLWHDDPVEPITNSSYKPSNWFSGSPDDNRSKATSPDGMSKSESKGALQRLEPPFGTDNGSAWDSDKDKNVSYTAAEMEKLSLSQKDIDEANKFKKISHDKKEAAPVNMSKLLSFGYAQDENKSPNDDDASSMTSEQTSTIAPEDELE", "length": 220, "header": "tr|E7FD23-1|E7FD23_DANRE Isoform 1 of Uncharacterized protein C7orf57 homolog OS=Danio rerio OX=7955 GN=si:dkey-276j7.1 PE=1 SV=1 CANONICAL=E7FD23-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7FD23", "url": "https://www.uniprot.org/uniprotkb/E7FD23" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009301673", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301673" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QAC0", "url": "https://www.uniprot.org/uniprotkb/F1QAC0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rbm33a", "url": "https://www.uniprot.org/uniprotkb/F1QAC0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-140106-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-90", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000068562", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000068562", "database": "Bgee", "categories": [ "Gene Expression" 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"MATIVGDDEFDEYDKPGAERSRRRRGEDDDDLESDFEEGDLLEDDWLSSKKNPSELSDEELNDDLLQSDEEDQNISGQGEAVSLNATLGMGTSVDFEDPGGYSGNAYKEGEGGQAGFSQDGQYEGDEYQAVDEGFEYRGEQNLAVYQDEVLDLQIDEPLDDDFQVDEYPTEYREQETNQQQVAEEEDEANEEETEEQDSSHVTELEEADNENDLEAEHEQDADVKEESDEEEEDDEESGRLRFKTERKDDTVVRLSDVASKRRNIPETLELSKEAKADLQKFEENERQRKQGRFGGRGRGGPYGDGGRGGMQGRGGMRGRGGAGGRGLGGRNDFHMFGMGGFRGDGVGGRGRINEQRPPLMQMNLGMQQQLRMTPPLQHHHHQSRLPGPRSSGGPGLFPDPGTPIAQQPLQMLMPHMSHRSPGPRTQQLNSPPRHSHAHPNQHQQHQQHHPKNIHINPHFRGPSSSPVQVPSMPPVQNQPRPNIASPRLSAPPDFQQHLGNFGPPLRPLPSQEPWRGPPPPHHQDQDHFFPGEPRFSGQHMFDQPGPAPLLNNSVLPMSGQGPPNFPPQGGLGGPGFGPLGLGQNQGPQSLALQHAGPPGPPGPRGFVGHRQPFSPPQQGPPFSPQHMPFGMQVRQRGLLQQPLHHDPQLTHQSLHQQHQQHRQDLPPQALLHSQPPPQHQTHHQHHPRDQHLSQPHFRQSISSGHRQMQSRPQGNQQRNNHARPRMTPPSPLQQIPPQRNSNLRELPIATSNNNTCPSVPSGQAKPVTKATQNVRQGPVARSGPAGKVGPLAQGQGSARAPLQPRVPEIKKAQPAAQSSTTPQNPDEDEETRQYRLKIEEQKRLREEVLRRKELRRQQQAGERKKELLERIGGQLPNQTQPTQNTTQPPTAQPPQPVPSLISNGTPQNPSPIVNSPRPNVKTRLLNTKPQAPASGWSGPQKPQSTGPNANLQGQYQPLQKRTIAPQNTQRPAAQGVGAQTKPVEGHGLGQPQPGGKRTVMQRTNSVESPQVPQKVRVVKLQGEQADASPSTAPSQQQQPPIGRPIPQQRLGPIRKVTMATGGVQNQQQAGRGVTNQTNRLVVRGRGRGRGTNRLLTQQNPRAQDHQPSTVCIEGLSTTTTNKQLLNLLNSIGPVERFNMLPEQRKAIAKFANPEHAVSFQHSFHRHMIDLSHIDVSIIDG", "length": 1181, "header": "tr|F1QAC0-1|F1QAC0_DANRE Isoform 1 of RNA-binding protein 33 isoform X1 OS=Danio rerio OX=7955 GN=rbm33a PE=1 SV=2 CANONICAL=F1QAC0-1" }, "isoforms": [ { "isoform_ac": "A0A1D5NS90-1", "url": "https://www.uniprot.org/uniprotkb/F1QAC0/entry#A0A1D5NS90-1", "sequence": { "sequence": "MATIVGDDEFDEYDKPGAERSRRRRGEDDDDLESDFEEGDLLEDDWLSSKKNPSELSDEELNDDLLQSDEEDQNISGQGEAVSLNATLGMGTSVDFEDPGGYSGNAYKEGEGGQAGFSQDGQYEGDEYQAVDEGFEYRGEQNLAVYQDEVLDLQIDEPLDDDFQVDEYPTEYREQETNQQQVAEEEDEANEEETEEQDSSHVTELEEADNENDLEAEHEQDADVKEESDEEEEDDEESGRLRFKTERKDDTVVRLSDVASKRRNIPETLELSKEAKADLQKFEENERQRKQGRFGGRGRGGPYGDGGRGGMQGRGGMRGRGGAGGRGLGGRNDFHMFGMGGFRGDGVGGRGRINEQRPPLMQMNLGMQQLRMTPPLQHHHHQSRLPGPRSSGGPGLFPDPGTPIAQQPLQMLMPHMSHRSPGPRTQQLNSPPRHSHAHPNQHQQHQQHHPKNIHINPHFRGPSSSPVQVPSMPPVQNQPRPNIASPRLSAPPDFQQHLGNFGPPLRPLPSQEPWRGPPPPHHQDQDHFFPGEPRFSGQHMFDQPGPAPLLNNSVLPMSGQGPPNFPPQGGLGGPGFGPLGLGQNQGPQSLALQHAGPPGPPGPRGFVGHRQPFSPPQQGPPFSPQHMPFGMQVRQRGLLQQPLHHDPQLTHQSLHQQHQQHRQDLPPQALLHSQPPPQHQTHHQHHPRDQHLSQPHFRQSISSGHRQMQSRPQGNQQRNNHARPRMTPPSPLQQIPPQRNSNLRELPIATSNNNTCPSVPSGQAKPVTKATQNVRQGPVARSGPAGKVGPLAQGQGSARAPLQPRVPEIKKAQPAAQSSTTPQNPDEDEETRQYRLKIEEQKRLREEVLRRKELRRQQQAGERKKELLERIGGQLPNQTQPTQNTTQPPTAQPPQPVPSLISNGTPQNPSPIVNSPRPNVKTRLLNTKPQAPASGWSGPQKPQSTGPNANLQGQYQPLQKRTIAPQNTQRPAAQGVGAQTKPVEGHGLGQPQPGGKRTVMQRTNSVESPQVPQKVRVVKLQGEQADASPSTAPSQQQQPPIGRPIPQQRLGPIRKVTMATGGVQNQQQAGRGVTNQTNRLVVRGRGRGRGTNRLLTQQNPRAQDHQPSTVCIEGLSTTTTNKQLLNLLNSIGPVERFNMLPEQRKAIAKFANPEHAVSFQHSFHRHMIDLSHIDVSIIDG", "length": 1180, "header": "tr|A0A1D5NS90-1|F1QAC0_DANRE Computationally mapped isoform of RNA-binding protein 33 isoform X1 OS=Danio rerio OX=7955 GN=rbm33a PE=1 SV=1 CANONICAL=F1QAC0-1" }, "locus": {} }, { "isoform_ac": "A0A8M2BDW6-1", "url": "https://www.uniprot.org/uniprotkb/F1QAC0/entry#A0A8M2BDW6-1", "sequence": { "sequence": "MATIVGDDEFDEYDKPGAERSRRRRGEDDDDLESDFEEGDLLEDDWLSSKKNPSELSDEELNDDLLQSDEEDQNISGQGEAVSLNATLGMGTSVDFEDPGGYSGNAYKEGEGGQAGFSQDGQYEGDEYQAVDEGFEYRGEQNLAVYQDEVLDLQIDEPLDDDFQVDEYPTEYREQETNQQQVAEEEDEANEEETEEQDSSHVTELEEADNENDLEAEHEQDADVKEESDEEEEDDEESGRLRFKTERKDDTVVRLSDVASKRRNIPETLELSKEAKADLQKFEENERQRKQGRFGGRGRGGPYGDGGRGGMQGRGGMRGRGGAGGRGLGGRNDFHMFGMGGFRGDGVGGRGRINEQRPPLMQMNLGMQQQLRMTPPLQHHHHQSRLPGPRSSGGPGLFPDPGTPIAQQPLQMLMPHMSHRSPGPRTQQLNSPPRHSHAHPNQHQQHQQHHPKNIHINPHFRGPSSSPVQVPSMPPVQNQPRPNIASPRLSAPPDFQQHLGNFGPPLRPLPSQEPWRGPPPPHHQDQDHFFPGEPRFSGQHMFDQPGPAPLLNNSVLPMSGQGPPNFPPQGGLGGPGFGPLGLGQNQGPQSLALQHAGPPGPPGPRGFVGHRQPFSPPQQGPPFSPQHMPFGMQGLLQQPLHHDPQLTHQSLHQQHQQHRQDLPPQALLHSQPPPQHQTHHQHHPRDQHLSQPHFRQSISSGHRQMQSRPQGNQQRNNHARPRMTPPSPLQQIPPQRNSNLRELPIATSNNNTCPSVPSGQAKPVTKATQNVRQGPVARSGPAGKVGPLAQGQGSARAPLQPRVPEIKKAQPAAQSSTTPQNPDEDEETRQYRLKIEEQKRLREEVLRRKELRRQQQAGERKKELLERIGGQLPNQTQPTQNTTQPPTAQPPQPVPSLISNGTPQNPSPIVNSPRPNVKTRLLNTKPQAPASGWSGPQKPQSTGPNANLQGQYQPLQKRTIAPQNTQRPAAQGVGAQTKPVEGHGLGQPQPGGKRTVMQRTNSVESPQVPQKVRVVKLQGEQADASPSTAPSQQQQPPIGRPIPQQRLGPIRKVTMATGGVQNQQQAGRGVTNQTNRLVVRGRGRGRGTNRLLTQQNPRAQDHQPSTVCIEGLSTTTTNKQLLNLLNSIGPVERFNMLPEQRKAIAKFANPEHAVSFQHSFHRHMIDLSHIDVSIIDG", "length": 1177, "header": "tr|A0A8M2BDW6-1|F1QAC0_DANRE Computationally mapped isoform of RNA-binding protein 33 isoform X1 OS=Danio rerio OX=7955 GN=rbm33a PE=1 SV=1 CANONICAL=F1QAC0-1" }, "locus": {} }, { "isoform_ac": "A0A8M3B4B4-1", "url": "https://www.uniprot.org/uniprotkb/F1QAC0/entry#A0A8M3B4B4-1", "sequence": { "sequence": "MATIVGDDEFDEYDKPGAERSRRRRGEDDDDLESDFEEGDLLEDDWLSSKKNPSELSDEELNDDLLQSDEEDQNISGQGEAVSLNATLGMGTSVDFEDPGGYSGNAYKEGEGGQAGFSQDGQYEGDEYQAVDEGFEYRGEQNLAVYQDEVLDLQIDEPLDDDFQVDEYPTEYREQETNQQQVAEEEDEANEEETEEQDSSHVTELEEADNENDLEAEHEQDADVKEESDEEEEDDEESGRLRFKTERKDDTVVRLSDVASKRRNIPETLELSKEAKADLQKFEENERQRKQGRFGGRGRGGPYGDGGRGGMQGRGGMRGRGGAGGRGLGGRNDFHMFGMGGFRGDGVGGRGRINEQRPPLMQMNLGMQQQLRMTPPLQHHHHQSRLPGPRSSGGPGLFPDPGTPIAQQPLQMLMPHMSHRSPGPRTQQLNSPPRHSHAHPNQHQQHQQHHPKNIHINPHFRGPSSSPVQVPSMPPVQNQPRPNIASPRLSAPPDFQQHLGNFGPPLRPLPSQEPWRGPPPPHHQDQDHFFPGEPRFSGQHMFDQPGPAPLLNNSVLPMSGQGPPNFPPQGGLGGPGFGPLGLGQNQGPQSLALQHAGPPGPPGPRGFVGHRQPFSPPQQGPPFSPQHMPFGMQVRQRGLLQQPLHHDPQLTHQSLHQQHQQHRQDLPPQALLHSQPPPQHQTHHQHHPRDQHLSQPHFRQSISSGHRQMQSRPQGNQQRNNHARPRMTPPSPLQQIPPQRNSNLRELPIATSNNNTCPSVPSGQAKPVTKATQNVRQGPVARSGPAGKVGPLAQGQGSARAPLQPRVPEIKKAQPAAQSSTTPQNPDEDEETRQYRLKIEEQKRLREEVLRRKELRRQQQAGERKKELLERIGGQLPNQTQPTQNTTQPPTAQPPQPVPSLISNGTPQNPSPIVNSPRPNVKTRLLNTKPQAPASGWSGPQKPQSTGPNANLQGQYQPLQKRTIAPQNTQRPAAQGVGAQTKPVEGHGLGQPQPGGKRTVMQRTNSVESPQVPQKVRVVKLQGEADASPSTAPSQQQQPPIGRPIPQQRLGPIRKVTMATGGVQNQQQAGRGVTNQTNRLVVRGRGRGRGTNRLLTQQNPRAQDHQPSTVCIEGLSTTTTNKQLLNLLNSIGPVERFNMLPEQRKAIAKFANPEHAVSFQHSFHRHMIDLSHIDVSIIDG", "length": 1180, "header": "tr|A0A8M3B4B4-1|F1QAC0_DANRE Computationally mapped isoform of RNA-binding protein 33 isoform X1 OS=Danio rerio OX=7955 GN=rbm33a PE=1 SV=1 CANONICAL=F1QAC0-1" }, "locus": {} }, { "isoform_ac": "A0AB32TZI0-1", "url": "https://www.uniprot.org/uniprotkb/F1QAC0/entry#A0AB32TZI0-1", "sequence": { "sequence": "MATIVGDDEFDEYDKPGAERSRRRRGEDDDDLESDFEEGDLLEDDWLSSKKNPSELSDEELNDDLLQSDEEDQNISGQGEAVSLNATLGMGTSVDFEDPGGYSGNAYKEGEGGQAGFSQDGQYEGDEYQAVDEGFEYRGEQNLAVYQDEVLDLQIDEPLDDDFQVDEYPTEYREQETNQQQVAEEEDEANEEETEEQDSSHVTELEEADNENDLEAEHEQDADVKEESDEEEEDDEESGRLRFKTERKDDTVVRLSDVASKRRNIPETLELSKEAKADLQKFEENERQRKQGRFGGRGRGGPYGDGGRGGMQGRGGMRGRGGAGGRGLGGRNDFHMFGMGGFRGDGVGGRGRINEQRPPLMQMNLGMQQQLRMTPPLQHHHHQSRLPGPRSSGGPGLFPDPGTPIAQQPLQMLMPHMSHRSPGPRTQQLNSPPRHSHAHPNQHQQHQQHHPKNIHINPHFRGPSSSPVQVPSMPPVQNQPRPNIASPRLSAPPDFQQHLGNFGPPLRPLPSQEPWRGPPPPHHQDQDHFFPGEPRFSGQHMFDQPGPAPLLNNSVLPMSGQGPPNFPPQGGLGGPGFGPLGLGQNQGPQSLALQHAGPPGPPGPRGFVGHRQPFSPPQQGPPFSPQHMPFGMQGLLQQPLHHDPQLTHQSLHQQHQQHRQDLPPQALLHSQPPPQHQTHHQHHPRDQHLSQPHFRQSISSGHRQMQSRPQGNQQRNNHARPRMTPPSPLQQIPPQRNSNLRELPIATSNNNTCPSVPSGQAKPVTKATQNVRQGPVARSGPAGKVGPLAQGQGSARAPLQPRVPEIKKAQPAAQSSTTPQNPDEDEETRQYRLKIEEQKRLREEVLRRKELRRQQQAGERKKELLERIGGQLPNQTQPTQNTTQPPTAQPPQPVPSLISNGTPQNPSPIVNSPRPNVKTRLLNTKPQAPASGWSGPQKPQSTGPNANLQGQYQPLQKRTIAPQNTQRPAAQGVGAQTKPVEGHGLGQPQPGGKRTVMQRTNSVESPQVPQKVRVVKLQGEADASPSTAPSQQQQPPIGRPIPQQRLGPIRKVTMATGGVQNQQQAGRGVTNQTNRLVVRGRGRGRGTNRLLTQQNPRAQDHQPSTVCIEGLSTTTTNKQLLNLLNSIGPVERFNMLPEQRKAIAKFANPEHAVSFQHSFHRHMIDLSHIDVSIIDG", "length": 1176, "header": "tr|A0AB32TZI0-1|F1QAC0_DANRE Computationally mapped isoform of RNA-binding protein 33 isoform X1 OS=Danio rerio OX=7955 GN=rbm33a PE=1 SV=1 CANONICAL=F1QAC0-1" }, "locus": {} }, { "isoform_ac": "A0AC58G5E0-1", "url": "https://www.uniprot.org/uniprotkb/F1QAC0/entry#A0AC58G5E0-1", "sequence": { "sequence": "MATIVGDDEFDEYDKPGAERSRRRRGEDDDDLESDFEEGDLLEDDWLSSKKNPSELSDEELNDDLLQSDEEDQNISGQGEAVSLNATLGMGTSVDFEDPGGYSGNAYKEGEGGQAGFSQDGQYEGDEYQAVDEGFEYRGEQNLAVYQDEVLDLQIDEPLDDDFQVDEYPTEYREQETNQQQVAEEEDEANEEETEEQDSSHVTELEEADNENDLEAEHEQDADVKEESDEEEEDDEESGRLRFKTERKDDTVVRLSDVASKRRNIPETLELSKEAKADLQKFEENERQRKQGRFGGRGRGGPYGDGGRGGMQGRGGMRGRGGAGGRGLGGRNDFHMFGMGGFRGDGVGGRGRINEQRPPLMQMNLGMQQLRMTPPLQHHHHQSRLPGPRSSGGPGLFPDPGTPIAQQPLQMLMPHMSHRSPGPRTQQLNSPPRHSHAHPNQHQQHQQHHPKNIHINPHFRGPSSSPVQVPSMPPVQNQPRPNIASPRLSAPPDFQQHLGNFGPPLRPLPSQEPWRGPPPPHHQDQDHFFPGEPRFSGQHMFDQPGPAPLLNNSVLPMSGQGPPNFPPQGGLGGPGFGPLGLGQNQGPQSLALQHAGPPGPPGPRGFVGHRQPFSPPQQGPPFSPQHMPFGMQGLLQQPLHHDPQLTHQSLHQQHQQHRQDLPPQALLHSQPPPQHQTHHQHHPRDQHLSQPHFRQSISSGHRQMQSRPQGNQQRNNHARPRMTPPSPLQQIPPQRNSNLRELPIATSNNNTCPSVPSGQAKPVTKATQNVRQGPVARSGPAGKVGPLAQGQGSARAPLQPRVPEIKKAQPAAQSSTTPQNPDEDEETRQYRLKIEEQKRLREEVLRRKELRRQQQAGERKKELLERIGGQLPNQTQPTQNTTQPPTAQPPQPVPSLISNGTPQNPSPIVNSPRPNVKTRLLNTKPQAPASGWSGPQKPQSTGPNANLQGQYQPLQKRTIAPQNTQRPAAQGVGAQTKPVEGHGLGQPQPGGKRTVMQRTNSVESPQVPQKVRVVKLQGEQADASPSTAPSQQQQPPIGRPIPQQRLGPIRKVTMATGGVQNQQQAGRGVTNQTNRLVVRGRGRGRGTNRLLTQQNPRAQDHQPSTVCIEGLSTTTTNKQLLNLLNSIGPVERFNMLPEQRKAIAKFANPEHAVSFQHSFHRHMIDLSHIDVSIIDG", "length": 1176, "header": "tr|A0AC58G5E0-1|A0AC58G5E0_DANRE Computationally mapped isoform of RNA-binding protein 33 isoform X6 OS=Danio rerio OX=7955 GN=rbm33a PE=1 SV=1 CANONICAL=F1QAC0-1" }, "locus": {} }, { "isoform_ac": "A0AC58G5F2-1", "url": "https://www.uniprot.org/uniprotkb/F1QAC0/entry#A0AC58G5F2-1", "sequence": { "sequence": "MATIVGDDEFDEYDKPGAERSRRRRGEDDDDLESDFEEGDLLEDDWLSSKKNPSELSDEELNDDLLQSDEEDQNISGQGEAVSLNATLGMGTSVDFEDPGGYSGNAYKEGEGGQAGFSQDGQYEGDEYQAVDEGFEYRGEQNLAVYQDEVLDLQIDEPLDDDFQVDEYPTEYREQETNQQQVAEEEDEANEEETEEQDSSHVTELEEADNENDLEAEHEQDADVKEESDEEEEDDEESGRLRFKTERKDDTVVRLSDVASKRRNIPETLELSKEAKADLQKFEENERQRKQGRFGGRGRGGPYGDGGRGGMQGRGGMRGRGGAGGRGLGGRNDFHMFGMGGFRGDGVGGRGRINEQRPPLMQMNLGMQQLRMTPPLQHHHHQSRLPGPRSSGGPGLFPDPGTPIAQQPLQMLMPHMSHRSPGPRTQQLNSPPRHSHAHPNQHQQHQQHHPKNIHINPHFRGPSSSPVQVPSMPPVQNQPRPNIASPRLSAPPDFQQHLGNFGPPLRPLPSQEPWRGPPPPHHQDQDHFFPGEPRFSGQHMFDQPGPAPLLNNSVLPMSGQGPPNFPPQGGLGGPGFGPLGLGQNQGPQSLALQHAGPPGPPGPRGFVGHRQPFSPPQQGPPFSPQHMPFGMQVRQRGLLQQPLHHDPQLTHQSLHQQHQQHRQDLPPQALLHSQPPPQHQTHHQHHPRDQHLSQPHFRQSISSGHRQMQSRPQGNQQRNNHARPRMTPPSPLQQIPPQRNSNLRELPIATSNNNTCPSVPSGQAKPVTKATQNVRQGPVARSGPAGKVGPLAQGQGSARAPLQPRVPEIKKAQPAAQSSTTPQNPDEDEETRQYRLKIEEQKRLREEVLRRKELRRQQQAGERKKELLERIGGQLPNQTQPTQNTTQPPTAQPPQPVPSLISNGTPQNPSPIVNSPRPNVKTRLLNTKPQAPASGWSGPQKPQSTGPNANLQGQYQPLQKRTIAPQNTQRPAAQGVGAQTKPVEGHGLGQPQPGGKRTVMQRTNSVESPQVPQKVRVVKLQGEADASPSTAPSQQQQPPIGRPIPQQRLGPIRKVTMATGGVQNQQQAGRGVTNQTNRLVVRGRGRGRGTNRLLTQQNPRAQDHQPSTVCIEGLSTTTTNKQLLNLLNSIGPVERFNMLPEQRKAIAKFANPEHAVSFQHSFHRHMIDLSHIDVSIIDG", "length": 1179, "header": "tr|A0AC58G5F2-1|A0AC58G5F2_DANRE Computationally mapped isoform of RNA-binding protein 33 isoform X4 OS=Danio rerio OX=7955 GN=rbm33a PE=1 SV=1 CANONICAL=F1QAC0-1" }, "locus": {} }, { "isoform_ac": "A0AC58G5F8-1", "url": "https://www.uniprot.org/uniprotkb/F1QAC0/entry#A0AC58G5F8-1", "sequence": { "sequence": "MATIVGDDEFDEYDKPGAERSRRRRGEDDDDLESDFEEGDLLEDDWLSSKKNPSELSDEELNDDLLQSDEEDQNISGQGEAVSLNATLGMGTSVDFEDPGGYSGNAYKEGEGGQAGFSQDGQYEGDEYQAVDEGFEYRGEQNLAVYQDEVLDLQIDEPLDDDFQVDEYPTEYREQETNQQQVAEEEDEANEEETEEQDSSHVTELEEADNENDLEAEHEQDADVKEESDEEEEDDEESGRLRFKTERKDDTVVRLSDVASKRRNIPETLELSKEAKADLQKFEENERQRKQGRFGGRGRGGPYGDGGRGGMQGRGGMRGRGGAGGRGLGGRNDFHMFGMGGFRGDGVGGRGRINEQRPPLMQMNLGMQQLRMTPPLQHHHHQSRLPGPRSSGGPGLFPDPGTPIAQQPLQMLMPHMSHRSPGPRTQQLNSPPRHSHAHPNQHQQHQQHHPKNIHINPHFRGPSSSPVQVPSMPPVQNQPRPNIASPRLSAPPDFQQHLGNFGPPLRPLPSQEPWRGPPPPHHQDQDHFFPGEPRFSGQHMFDQPGPAPLLNNSVLPMSGQGPPNFPPQGGLGGPGFGPLGLGQNQGPQSLALQHAGPPGPPGPRGFVGHRQPFSPPQQGPPFSPQHMPFGMQGLLQQPLHHDPQLTHQSLHQQHQQHRQDLPPQALLHSQPPPQHQTHHQHHPRDQHLSQPHFRQSISSGHRQMQSRPQGNQQRNNHARPRMTPPSPLQQIPPQRNSNLRELPIATSNNNTCPSVPSGQAKPVTKATQNVRQGPVARSGPAGKVGPLAQGQGSARAPLQPRVPEIKKAQPAAQSSTTPQNPDEDEETRQYRLKIEEQKRLREEVLRRKELRRQQQAGERKKELLERIGGQLPNQTQPTQNTTQPPTAQPPQPVPSLISNGTPQNPSPIVNSPRPNVKTRLLNTKPQAPASGWSGPQKPQSTGPNANLQGQYQPLQKRTIAPQNTQRPAAQGVGAQTKPVEGHGLGQPQPGGKRTVMQRTNSVESPQVPQKVRVVKLQGEADASPSTAPSQQQQPPIGRPIPQQRLGPIRKVTMATGGVQNQQQAGRGVTNQTNRLVVRGRGRGRGTNRLLTQQNPRAQDHQPSTVCIEGLSTTTTNKQLLNLLNSIGPVERFNMLPEQRKAIAKFANPEHAVSFQHSFHRHMIDLSHIDVSIIDG", "length": 1175, "header": "tr|A0AC58G5F8-1|A0AC58G5F8_DANRE Computationally mapped isoform of RNA-binding protein 33 isoform X8 OS=Danio rerio OX=7955 GN=rbm33a PE=1 SV=1 CANONICAL=F1QAC0-1" }, "locus": {} }, { "isoform_ac": "F1QAC0-1", "url": "https://www.uniprot.org/uniprotkb/F1QAC0/entry#F1QAC0-1", "sequence": { "sequence": "MATIVGDDEFDEYDKPGAERSRRRRGEDDDDLESDFEEGDLLEDDWLSSKKNPSELSDEELNDDLLQSDEEDQNISGQGEAVSLNATLGMGTSVDFEDPGGYSGNAYKEGEGGQAGFSQDGQYEGDEYQAVDEGFEYRGEQNLAVYQDEVLDLQIDEPLDDDFQVDEYPTEYREQETNQQQVAEEEDEANEEETEEQDSSHVTELEEADNENDLEAEHEQDADVKEESDEEEEDDEESGRLRFKTERKDDTVVRLSDVASKRRNIPETLELSKEAKADLQKFEENERQRKQGRFGGRGRGGPYGDGGRGGMQGRGGMRGRGGAGGRGLGGRNDFHMFGMGGFRGDGVGGRGRINEQRPPLMQMNLGMQQQLRMTPPLQHHHHQSRLPGPRSSGGPGLFPDPGTPIAQQPLQMLMPHMSHRSPGPRTQQLNSPPRHSHAHPNQHQQHQQHHPKNIHINPHFRGPSSSPVQVPSMPPVQNQPRPNIASPRLSAPPDFQQHLGNFGPPLRPLPSQEPWRGPPPPHHQDQDHFFPGEPRFSGQHMFDQPGPAPLLNNSVLPMSGQGPPNFPPQGGLGGPGFGPLGLGQNQGPQSLALQHAGPPGPPGPRGFVGHRQPFSPPQQGPPFSPQHMPFGMQVRQRGLLQQPLHHDPQLTHQSLHQQHQQHRQDLPPQALLHSQPPPQHQTHHQHHPRDQHLSQPHFRQSISSGHRQMQSRPQGNQQRNNHARPRMTPPSPLQQIPPQRNSNLRELPIATSNNNTCPSVPSGQAKPVTKATQNVRQGPVARSGPAGKVGPLAQGQGSARAPLQPRVPEIKKAQPAAQSSTTPQNPDEDEETRQYRLKIEEQKRLREEVLRRKELRRQQQAGERKKELLERIGGQLPNQTQPTQNTTQPPTAQPPQPVPSLISNGTPQNPSPIVNSPRPNVKTRLLNTKPQAPASGWSGPQKPQSTGPNANLQGQYQPLQKRTIAPQNTQRPAAQGVGAQTKPVEGHGLGQPQPGGKRTVMQRTNSVESPQVPQKVRVVKLQGEQADASPSTAPSQQQQPPIGRPIPQQRLGPIRKVTMATGGVQNQQQAGRGVTNQTNRLVVRGRGRGRGTNRLLTQQNPRAQDHQPSTVCIEGLSTTTTNKQLLNLLNSIGPVERFNMLPEQRKAIAKFANPEHAVSFQHSFHRHMIDLSHIDVSIIDG", "length": 1181, "header": "tr|F1QAC0-1|F1QAC0_DANRE Isoform 1 of RNA-binding protein 33 isoform X1 OS=Danio rerio OX=7955 GN=rbm33a PE=1 SV=2 CANONICAL=F1QAC0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100149667", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100149667", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A6H2EEJ8-1", "protein_name": "Uncharacterized protein", "gene_name": "Dmel\\CG2186", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSDINDDLLNYELGDDIDDQALLGADEDELLLSDEELEKDVTSEVKQQMRAEAEEWAQEQIRQHERKHKEQLQADATAATEVTVAATATAEVAPTLRAQPELASSPAPDPVPAKPLVAQVEKHVDTAHAAVAAEPAKELVSASRSESPQQQAKEEAPPADCAEKEATQNNGNSEEQAENAGSQSEAERGLGLCSLLASSQESLPSASSASVISDPREDDEEREERTNYKTASERSDNNLRQQQEHAHMSPYQHQQRRLHGHGDKPRVGGGGRFMHGQQQQQQQQQSQMGKPPRGIGTRHHLLRNPSPSFGIQQQRMGMAGMQPPPQRYGMPGNAPPPQHLALMSTPVGAAPTAACLLPLTVPVTPLTLSIPQAHPSHQVHQQQQQTLSNPTFIPIPGQYPATQPPNQSPQQAPTNTQQPHSAPASPLHTPTHSHMMHHSHNPNGGVLHHLLPHPHEQVRVGLLQPPPLAYAPNPGGYRNGALLGPGPGPGLHQQHQSPHQQQSGMRPPLYRNAPPSYGYDQGHPPQHPQQFMRPHNGWRPQGDNARMQRPPLQTLPPHMMPGAPPNYANGMGMRGPPPQQQQSQQPPQQQPAPQQAGNPLQQAVNPGQPPQQPNGPPQQQGSSSVPRVSKVLINPNFKGGVEAATNKFIKETHFMPAINSEAELLRQQVEFINKNRQYIEKRRMERSPPSSGSSTGAASSGQAGERRRTRSRSRSRGRSYSPVKRVERERERERERERDRERDRERDRERYGANRAAGNRGFRRASSRDRDENRGAASTASAQGAGGSASSGAAPPKRRRSGSAGGGTARNPFSGEPRGRPSETGSRSMPSDEDEETRNYRLEIEKQKQLREKIMRDKELKRRRAAEEKLHEEKRAEQHNTSPARDDQEVAAGQGSAAPTPAASKHRPTASAGERKVISLKRRDDQDASSVRSRQAQGSQSNAQAGQGQQQQQAARKQLTAAKIAPEAKRSITDHLAPSSKQHHHHHQQHHQTAAAPARTVVLGSGAVAGGTPPKPRDKLRLGTPSDDEVELDYDDDDLLLDEEDRLLATPSPPPQKASSKRSATPEPLVVKRNHKAMRGGSSTSAPSFSSNQRRVVLKPTSNGSSSSGGDQQQLSHSGRQRDRRRGGEDSALQRKGGVGSVGGSSSSGSGGGIFDRLEKRVAVSGGGSSGGGGGSSHKQRSKAPARIVLKHD", "length": 1193 }, "evidence": [ { "id": "HGNC:27223", "url": "https://alliancegenome.org/gene/HGNC:27223#orthology", "database": "AGR" }, { "id": "MGI:1919670", "url": "https://alliancegenome.org/gene/MGI:1919670#orthology", "database": "AGR" }, { "id": "F1QAC0", "url": "https://omabrowser.org/oma/group/F1QAC0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8M6Z1Q1-1", "protein_name": "Uncharacterized protein rbm33b isoform X1", "gene_name": "rbm33b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MQKCYSTSLYSILTVKCYKPFKHKLTWFLRFTENSNGVYDKPGREKFFRGREKVQDMNSDSEEDILVDDWLTSKQDFLDTSDEELNDDLLRSDDENETMSSSKPKHQAIALPHVVCETSHPAKDQAICPKEEHTEVDHGEVLDIEINAPSGDEFQEPGDYGVHQQASVKVDVKDDVKLVSSLHKESKKGVSEFRAGLSLQPTSHHLIPSSRGQPDPEEPRIRPCRSPEPAFPGQHMFDQQHCASVLDTNPLLAGPAPMGSIQPGGNESDPWRPSPALQEPSDLSKPGTPHRGHCSLQKHPSAPSGCRFNAPSGQSQVTQKPAVLVRAVARMVQNAKPMAVARGMPITARQPACAKSTITAKTPPAPGTVGRNVGQKVKVEPQTPRATQKHPAKPLNMTNDKEREEYILYMQKLEEQMHLRRQVIKHKERMRSLRAANKRRLRLEHFQTDLSTAHCWNNNQNQQKPPCFLSSYPTNAMPQQHFYNPHDCLVLQCHPQLHPRPPQQQMYQILVPAFQPPCHQALSAQGTPAEVQYNQACHSGTGRVVLQKMEQFADHMSLQYSIDEARFAGLQDVQPGRKRMIEQRISDGPVPAKSKVVQYFTTSSRIGSSSSDFKPAMSEEAKSVTETNRRTVTLIQESSPLSFLQHGLKLTCPIQNKVAISGNEHSAFIPLGSGLKTQSVTAQTSFIVRLNH", "length": 692 }, "evidence": [ { "id": "HGNC:27223", "url": "https://alliancegenome.org/gene/HGNC:27223#orthology", "database": "AGR" }, { "id": "MGI:1919670", "url": "https://alliancegenome.org/gene/MGI:1919670#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZTA8-1", "protein_name": "RNA-binding protein 33", "gene_name": "Rbm33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAALGAGGGAGAGDDDFDQFDKPGAERSWRRRAADEDWDSELEDDLLGEDLLSGKKNQSDLSDEELNDDLLQSDNEDEENFSSQGVTISLNTTSGIVTSFELSDNTNDQSGEQESEYEQGDDELAYHKPEEQELYTQEYPEEGQYEGHDTELTEDQIEYGDEPEEEQLYSDEVLDIEINEPLDEFTDEEYLQAYGGQQGLQVREDCEAEDDLDEITDSQVASETHEGGMETLELQKDIKEESDEEDDDDEESGRLRFKTERKEGTIIRLSDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYGSRRGGRRGGSLMCRGMGDQRRDNSERGRMKEHRPALLPTQPPVVAHSPRLIPPPQQQPPPPPPPPQQQPIRSLFQQQQLQPLLPLQHPHHPSPPQGVHMPPQIETPRMMLTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFNQPPRLPLQDQWRAPPPPQERDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATARPFIPPRQPFLPSPGQPFLPTHAQPNLQGPLHPPLPPPHQPQPQPQQPQQQPQHHQHQPPLQPPLQPPHQPPPQHQPPPQHQPQQHQHHHHLSAPPPPLMPMSQPQFRPHVQTAQPQSNSSRMQCTPRQGLRHNTASQNISKRPMQQMQPTAPRNSNLRELPIAPSHVLEMSGNRCSSTPAAQVKSIANTSPPCRAVVASRSSQGKTDAKAKPLSPGAQPKEEAKAEAEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQQQQQQQQQQQQIYGSQTPMEQEELAATPSPTNGNPLLPFPGTQCRQNVKTRLLVKNQDVTAANVQPKAVNFVPPGANMQHQGQHLRPLKHLRQLPHKVLHVKPMDMEETPHSPQAARVTSLQGRPQDTKPGVKRTVMHRANSGGGGDGPHVSSKVRVIKLSGGQGGESDGFSHTEGQPQRLPQPPDMRQQPTRKVTLTKGVPQQPQHLPVGPHMYPAIPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNKQNLRVVECKPQPCVVSVEGLSSSTTDVQLKSLLMSVGPIQSLQMLPQQRKAIAKFKEPAHALAFQQKFHRHMIDLSHINVALIVE", "length": 1223 }, "evidence": [ { "id": "HGNC:27223", "url": "https://alliancegenome.org/gene/HGNC:27223#orthology", "database": "AGR" }, { "id": "MGI:1919670", "url": "https://alliancegenome.org/gene/MGI:1919670#orthology", "database": "AGR" }, { "id": "F1QAC0", "url": "https://omabrowser.org/oma/group/F1QAC0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96EV2-1", "protein_name": "RNA-binding protein 33", "gene_name": "RBM33", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAALGASGGAGAGDDDFDQFDKPGAERSWRRRAADEDWDSELEDDLLGEDLLSGKKNQSDLSDEELNDDLLQSDNEDEENFSSQGVTISLNATSGMVTSFELSDNTNDQSGEQESEYEQEQGEDELVYHKSDGSELYTQEYPEEGQYEGHEAELTEDQIEYVEEPEEEQLYTDEVLDIEINEPLDEFTGGMETLELQKDIKEESDEEEEDDEESGRLRFKTERKEGTIIRLSDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYSSRRGGRRGGPLMCRGVGDQRRESTERGRMKDHRPALLPTQPPVVPQAPPPPPPPPQQQPIRSLFQPQPLQPLLPVQHPHHPSPPQGMHMPPQLETPRMMMTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFSQPPRLPLQDQWRAPPPPQDRDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNLQGPLHPPLPPPHQPQPQQPQQQPPPQHQPPHQPPHQPPPQHQPPPQHPPQHPPQHQHHHHHHHLSVPPPPLMPMSQPQFRPHVQTAQPQASSSRMQCPQRQGLRHNTTSQNVSKRPMQQMQPTAPRNSNLRELPIAPSHVIEMSSSRCSATPSAQVKPIVSASPPSRAVAGSRSSQGKTEVKVKPASPVAQPKEEAKTETEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQLYAPPPPAEQEEQALSPSPTNGNPLLPFPGAQVRQNVKNRLLVKNQDVSISNVQPKTSNFVPSSANMQYQGQQMKALKHLRQTRTVPQSQTQPLHKVLPIKPADVEEPAVPQTPRVASIQGRPQDTKPGVKRTVTHRTNSGGGDGPHISSKVRVIKLSGGGGESDGFFHPEGQPQRLPQPPEVGPQPARKVTLTRGGLQQPPHLPAGPHAHSPVPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNKQNLRVVECKPQPCVVSVEGLSSSTTDAQLKSLLMSVGPIQSLQMLPQQRKAIAKFKEPAHALAFQQKFHRHMIDLSHINVALIVE", "length": 1170 }, "evidence": [ { "id": "HGNC:27223", "url": "https://alliancegenome.org/gene/HGNC:27223#orthology", "database": "AGR" }, { "id": "MGI:1919670", "url": "https://alliancegenome.org/gene/MGI:1919670#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-90#orthology", "database": "AGR" }, { "id": "F1QAC0", "url": "https://omabrowser.org/oma/group/F1QAC0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CXK9-1", "protein_name": "RNA-binding protein 33", "gene_name": "Rbm33", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAALGAGGGAGAGDDDFDQFDKPGAERSWRRRAADEDWDSELEDDLLGEDLLSGKKNQSDLSDEELNDDLLQSDNEEEENFSSQGVTISLNTTSGIVTSFELSDNTNDQSGEQESEYEQGDDELAYHKPEEQELYTQEYPEEGQYEGHDAELTEDQIEYGDEPEEEQLYSDEVLDIEINEPLDEFTDEEYLQAYGGQQGLQVREDCEAEDDLDEITDSQVASETHEGGMETLELQKDIKEESDEEDDDDEESGRLRFKTERKEGTIIRLSDVTRERRNIPETLELSAEAKAALLEFEERERQHKQGRYGSRRGGRRGGSLMCRGMGDQRRDNSERGRMKEHRPALLPTQPSVVAHSPRLIPPPQPQPPPPPPPPPPQQQPIRSLFQQQQLQPLLPLQHPHHPSPPQGVHMPPQIETPRMMLTPPPVTPQQPKNIHINPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPPEFPQHTPGPVPNSFNQPPRLPLQDQWRAPPPPQERDPFFLGVSGEPRFPSHLFLEQRSPPPPPPPPTLLNSSHPVPTQSPLPFTQPGPAFNQQGQQPVFPRERPVRPALQPPGPVGILHFSQPGSATARPFIPPRQPFLPSPGQPFLPTHAQPNLQGPLHPPLPPPHQPQPQPQQPQQQPQHHQHQPPLQPPLQPPHQPPPQHQPPPQHQPQQHQHHHHLSAPPPPLMPMSQPQFRPHVQTAQPQPSSSRMQCTPHQGLRHNAASQNISKRPMQQMQPTAPRNSNLRELPIAPSHVLEMSGNRCSSTPVAQVKSIVNTSPPCRAVVSSRSSQGNTDAKAKPLSPEAQPKEEAKPEAEFPDEDEETRLYRLKIEEQKRLREEILKQKELRRQQQAGARKKELLERLAQQQQQQQQQQHQPQQQQQQPQQIYGSQTSMEQEELAATPSPTNGNPLLPFPGAQCRQNVKTRLLVKNQDITTASVQPKAVNFVPPGANVQHQGQHLRPLKHLRQLPHKVLQVKPMDMEETPHSPQAARVTSLQGRPQDTKPGVKRTVMHRANSGGGGDGPHVSSKVRVIKLSGGQGGESDGFSHTEGQPQRLPQPPDMRQQPTRKVTLTKGVPQQPQHLPVGPHMYPAIPPGIKSIQGIHPAKKAIMHGRGRGVAGPMGRGRLMPNKQNLRVVECKPQPCVVSVEGLSSSTTDVQLKSLLMSVGPIQSLQMLPQQRKAIAKFKEPAHALAFQQKFHRHMIDLSHINVALIVE", "length": 1231 }, "evidence": [ { "id": "HGNC:27223", "url": "https://alliancegenome.org/gene/HGNC:27223#orthology", "database": "AGR" }, { "id": "MGI:1919670", "url": "https://alliancegenome.org/gene/MGI:1919670#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-90", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-90#orthology", "database": "AGR" }, { "id": "F1QAC0", "url": "https://omabrowser.org/oma/group/F1QAC0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "F1QAC0", "url": "https://www.uniprot.org/uniprotkb/F1QAC0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1076, "end_pos": 1078, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" }, { "start_pos": 754, "end_pos": 756, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" }, { "start_pos": 878, "end_pos": 880, "annotation": "n_glycosylation_sequon" }, { "start_pos": 885, "end_pos": 887, "annotation": "n_glycosylation_sequon" }, { "start_pos": 904, "end_pos": 906, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1QAC0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QAC0" }, { "id": "SM00360", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00360" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 1110, "end_pos": 1177, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1076, "end_pos": 1078 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 74, "end_pos": 76 }, { "start_pos": 754, "end_pos": 756 }, { "start_pos": 85, "end_pos": 87 }, { "start_pos": 878, "end_pos": 880 }, { "start_pos": 885, "end_pos": 887 }, { "start_pos": 904, "end_pos": 906 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F5D2-1", "uniprot_ac": "E7F5D2", "uniprot_id": "E7F5D2_DANRE", "mass": { "chemical_mass": 56621.0, "monoisotopic_mass": 56621.0 }, "refseq": { "ac": "XP_698642", "name": "serine incorporator 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698642" }, "gene_names": [ { "name": "serinc4", "type": "recommended", "evidence": [ { "id": "E7F5D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5D2" } ] }, { "name": "serinc4", "type": "synonym", "evidence": [ { "id": "XP_698642", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698642" } ] } ], "protein_names": [ { "name": "Serine incorporator 4 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F5D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5D2/entry#names_and_taxonomy" } ] }, { "name": "serine incorporator 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_698642", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698642" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_698642.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_698642", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698642" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F5D2", "url": "https://www.uniprot.org/uniprotkb/E7F5D2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "serinc4", "url": "https://www.uniprot.org/uniprotkb/E7F5D2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-121031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121031-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000044815", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000044815", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "570112", "url": "https://www.ncbi.nlm.nih.gov/gene/570112", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005016", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005016", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570112", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570112", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHNFWFL", "url": "https://omabrowser.org/oma/group/IHNFWFL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BE25", "url": "https://www.orthodb.org/?gene=A0A8M2BE25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F5D2", "url": "https://www.orthodb.org/?gene=E7F5D2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10383", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10383", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10383:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10383:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03348", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03348", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-977347", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-977347", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_698642", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698642", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BE25", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BE25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BE25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BE25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F5D2", "url": "https://www.uniprot.org/uniprotkb/E7F5D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F5D2-1", "url": "https://www.uniprot.org/uniprotkb/E7F5D2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-121031-1", "url": "https://zfin.org/ZDB-GENE-121031-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSTAQALHHSGVYNYFLNMVAYQICCCCGPAPCSLCCSFCPPVKSSTSTRIMYTLFHILACTVSCLMLSKTVSEAVRENVPFFNVVCDEAHGGGDCQMLVGYSAVYRVCFGTACFYLMMAIFLIDVKSSQDFRALIHNGFWFLKFITMLGMIAAAFFIPTESFLHAWHYVGVVGGFSFILIQLILITAFAHTWNKNWLTGAAENKRWYVAVMCATLFFYTIATMAFTFMYKYYTHPAGCHLNKALLWTNLALCTIMSFIAITPCVQQKKPRSGILQASIICCYVMYLTFSALSSRPPEKVEYQGVNITICYPKVSRDEIQNEGNAVAIMGAAIMYCCVLFACNEASYLAEVFGPFWMIKVYRYEFQKASCCFCCPEAEDEEEFVIDENKGCQKVVHNETQRVAYSYFFFHFVFFLASLYVMMTLTNWFSYETAVLETTFTHGSYSTFWVKLSSCWACVVLYLWLLLGPLCQCQSDPKRPRRARIKRRIAAHRHVSVSV", "length": 498, "header": "tr|E7F5D2-1|E7F5D2_DANRE Isoform 1 of Serine incorporator 4 isoform X1 OS=Danio rerio OX=7955 GN=serinc4 PE=3 SV=1 CANONICAL=E7F5D2-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BE25-1", "url": "https://www.uniprot.org/uniprotkb/E7F5D2/entry#A0A8M2BE25-1", "sequence": { "sequence": "MCCRCCWPQICCCCGPAPCSLCCSFCPPVKSSTSTRIMYTLFHILACTVSCLMLSKTVSEAVRENVPFFNVVCDEAHGGGDCQMLVGYSAVYRVCFGTACFYLMMAIFLIDVKSSQDFRALIHNGFWFLKFITMLGMIAAAFFIPTESFLHAWHYVGVVGGFSFILIQLILITAFAHTWNKNWLTGAAENKRWYVAVMCATLFFYTIATMAFTFMYKYYTHPAGCHLNKALLWTNLALCTIMSFIAITPCVQQKKPRSGILQASIICCYVMYLTFSALSSRPPEKVEYQGVNITICYPKVSRDEIQNEGNAVAIMGAAIMYCCVLFACNEASYLAEVFGPFWMIKVYRYEFQKASCCFCCPEAEDEEEFVIDENKGCQKVVHNETQRVAYSYFFFHFVFFLASLYVMMTLTNWFSYETAVLETTFTHGSYSTFWVKLSSCWACVVLYLWLLLGPLCQCQSDPKRPRRARIKRRIAAHRHVSVSV", "length": 484, "header": "tr|A0A8M2BE25-1|E7F5D2_DANRE Computationally mapped isoform of Serine incorporator 4 isoform X1 OS=Danio rerio OX=7955 GN=serinc4 PE=3 SV=1 CANONICAL=E7F5D2-1" }, "locus": {} }, { "isoform_ac": "E7F5D2-1", "url": "https://www.uniprot.org/uniprotkb/E7F5D2/entry#E7F5D2-1", "sequence": { "sequence": "MSTAQALHHSGVYNYFLNMVAYQICCCCGPAPCSLCCSFCPPVKSSTSTRIMYTLFHILACTVSCLMLSKTVSEAVRENVPFFNVVCDEAHGGGDCQMLVGYSAVYRVCFGTACFYLMMAIFLIDVKSSQDFRALIHNGFWFLKFITMLGMIAAAFFIPTESFLHAWHYVGVVGGFSFILIQLILITAFAHTWNKNWLTGAAENKRWYVAVMCATLFFYTIATMAFTFMYKYYTHPAGCHLNKALLWTNLALCTIMSFIAITPCVQQKKPRSGILQASIICCYVMYLTFSALSSRPPEKVEYQGVNITICYPKVSRDEIQNEGNAVAIMGAAIMYCCVLFACNEASYLAEVFGPFWMIKVYRYEFQKASCCFCCPEAEDEEEFVIDENKGCQKVVHNETQRVAYSYFFFHFVFFLASLYVMMTLTNWFSYETAVLETTFTHGSYSTFWVKLSSCWACVVLYLWLLLGPLCQCQSDPKRPRRARIKRRIAAHRHVSVSV", "length": 498, "header": "tr|E7F5D2-1|E7F5D2_DANRE Isoform 1 of Serine incorporator 4 isoform X1 OS=Danio rerio OX=7955 GN=serinc4 PE=3 SV=1 CANONICAL=E7F5D2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:570112", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570112", "resource": "KEGG Pathway" }, { "id": "R-DRE-977347", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-977347", "resource": "Reactome", "description": "Serine metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A6NH21-1", "protein_name": "Serine incorporator 4", "gene_name": "SERINC4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGAKAGPSPGTSLGLAQQHSGGSSVLVKSPFCQVCCCGPAPCASCCHSRWPSLTASTCSRLFYILLHVGASAICCLLLSRTVVERVWGKTHRIQMPSGLCAHLFGLSDCPVLSGSGAVYRVCAGTATFHLLQAVLLVHLHSPTSPRAQLHNSFWLLKLLFLLGLCAIAFCIPDEHLFPAWHYIGICGGFAFILLQLVLITAFAHSWNKNWQTGAAQDCSWFLAVLLATLGFYSMAGVGAVLLFHYYTHPAGCLLNKMLLSLHLCFCGLISFLSIAPCIRLKQPRSGLLQASVISCYIMYLTFSALSSRPPERVILQGQNHTLCLPGLSKMEPQTPDISLAMLSASIMYACVLFACNEASYLAEVFGPLWIVKVYSYEFQKPSLCFCCPETVEADKGQRGGAARPADQETPPAPPVQVQHLSYNYSAFHFVFFLASLYVMVTLTNWFSYEGAELEKTFIKGSWATFWVKVASCWACVLLYLGLLLAPLCWPPTQKPQPLILRRRRHRIISPDNKYPPV", "length": 518 }, "evidence": [ { "id": "MGI:2441842", "url": "https://alliancegenome.org/gene/MGI:2441842#orthology", "database": "AGR" }, { "id": "HGNC:32237", "url": "https://alliancegenome.org/gene/HGNC:32237#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121031-1#orthology", "database": "AGR" }, { "id": "E7F5D2", "url": "https://omabrowser.org/oma/group/E7F5D2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A8WCG0-1", "protein_name": "Serine incorporator 4", "gene_name": "Serinc4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGAKDITGRSTTQGFAQQHGGVSDVVVKTPFYQVSCCGPVSWTSGCHSLTESTCSRLFYILLHMGASAICCLLLSKTVVERVWGKAHGIQMPSVLCAHLFGNSDCPVLSGSGAVYRVCAGTATFHLLQAVLLVRLHSPTSPRAQLHNSFWSLKLLFLLGLCTAAFCIPDEHLFPAWHYIGICGGFTFILLQLVLITAFAQSWNKNWQTGAAQDCSWFLGVLLATLGFYSMAGVGAVLLFHHYTHPDGCLLNKMLLSLHLCFCGLLSLLSIAPCIRLRQPNSGLLQASIISCYIMYLTFSALSSRPPETIIFQGQNHTLCLPGQNKMEPQIPDASVAVFSASIMYACVLFACNEASYLAQLFGPLWIIKVYKYEFQKPSVCFCCPQTVEPEDGQGSRARPADQETPPAAQVQSQHLSYSYSGFHFAFFLASLYVMVTLTNWFSYEEAELEKTFTKGSWATFWVKVASCWACVLLYLGLLLAPLLAHHSESPPP", "length": 492 }, "evidence": [ { "id": "MGI:2441842", "url": "https://alliancegenome.org/gene/MGI:2441842#orthology", "database": "AGR" }, { "id": "HGNC:32237", "url": "https://alliancegenome.org/gene/HGNC:32237#orthology", "database": "AGR" }, { "id": "E7F5D2", "url": "https://omabrowser.org/oma/group/E7F5D2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12116-1", "protein_name": "Membrane protein TMS1", "gene_name": "TMS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGAVISLPVSMAGSFVASCFGGCCSNLVTKTASSLGSSSLGTRLLYAVWLLLNSLISWVSYSANKSILWPGKTCTGTGECGFFTVHRLNFALGCLHLILALVLTGVKSTNDVRAALQNSWWSLKFILYLCLIVLSFVIPNDFYIFFSKWVSVPSGAIFILVGLILLVDFAHEWAETCISHVESEDEDSSFWQRFLVLGTTSMYTASIIMTVVMYVMFCHQQCNMNQTAVTVNLILTVITLVLSVNPKIQEANPKSGLAQSSMVSVYCTYLTMSAMSSEPDDKMCNPLVRSSGTRKFSIILGSLFTFIAIAYTTTRAAANSAFQGTNTNGAIYLGNDIEYEGLGGQTRNQLRYEAIKQAVEEGSLPESALYDTAWLGTSSPTGAMDNQNDDERTGTKYNYTLFHVIFFLATQWIAILLTINVTQDDVGDFIPVGRTYFYSWVKIVSAWICYALYGWTVVAPAIMPDRFDYENYY", "length": 473 }, "evidence": [ { "id": "MGI:2441842", "url": "https://alliancegenome.org/gene/MGI:2441842#orthology", "database": "AGR" }, { "id": "HGNC:32237", "url": "https://alliancegenome.org/gene/HGNC:32237#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5XK03-1", "protein_name": "Serine incorporator 4", "gene_name": "Serinc4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMGAKVVTGRSTTQGLAQQHGGVSNVVETPFNQASCCGPVSWTSGCHSLTESRCSRLLYILLHVGASAICCLLLSKTVVERVWGKAHGIQMPSVLCAHLFGSSDCPVLSGSGAVYRVCAGTATFHLLQAVLLVRLHSPTNPRAQLHNSFWSLKLLFLLGLCVVAFCIPDEDLFPAWHYIGICGGFTFILLQLVLITAFAQSWNKNWQTGAAQDCSWLLGVSLATLGFYSMAGVGAVLLFHQYTHPDGCLLNKMLLSLHLCFCGLLSLLSIAPCIRRKQPNSGLLQASIISCYIMYLTFSALSSRPPETITFQGQNHTLCLPGRNKMEPQIPDTSVAVFSAGIMYACVLFACNEASYLAELFGPLWIIKVYKYEFQKPSVCFCCPQTVEPEDGQRSRARSADQETPPAAQVQSQHLSYSYSGFHFAFFLASLYVMVTLTNWFSYEEAELEKTFTKGSWATFWVKVASCWACVLLYLGLLLAPLLAPHSESPPP", "length": 492 }, "evidence": [ { "id": "MGI:2441842", "url": "https://alliancegenome.org/gene/MGI:2441842#orthology", "database": "AGR" }, { "id": "HGNC:32237", "url": "https://alliancegenome.org/gene/HGNC:32237#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121031-1#orthology", "database": "AGR" }, { "id": "E7F5D2", "url": "https://omabrowser.org/oma/group/E7F5D2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7F5D2", "url": "https://www.uniprot.org/uniprotkb/E7F5D2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 306, "end_pos": 308 }, { "start_pos": 397, "end_pos": 399 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FFH0-1", "uniprot_ac": "E7FFH0", "uniprot_id": "E7FFH0_DANRE", "mass": { "chemical_mass": 31829.0, "monoisotopic_mass": 31829.0 }, "refseq": { "ac": "XP_684802", "name": "ankyrin repeat and SOCS box protein 13 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684802" }, "gene_names": [ { "name": "asb13b", "type": "recommended", "evidence": [ { "id": "E7FFH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FFH0" } ] }, { "name": "asb13b", "type": "synonym", "evidence": [ { "id": "XP_684802", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684802" } ] } ], "protein_names": [ { "name": "Ankyrin repeat and SOCS box protein 13 isoform X1", "type": "synonym", "evidence": [ { "id": "E7FFH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FFH0/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat and SOCS box protein 13 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_684802", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684802" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_684802.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_684802", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684802" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FFH0", "url": "https://www.uniprot.org/uniprotkb/E7FFH0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "asb13b", "url": "https://www.uniprot.org/uniprotkb/E7FFH0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091118-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-116", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000089833", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000089833", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd03729", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd03729", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "556808", "url": "https://www.ncbi.nlm.nih.gov/gene/556808", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037334", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037334", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051573", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051573", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556808", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556808", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AGFWVER", "url": "https://omabrowser.org/oma/group/AGFWVER/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BE81", "url": "https://www.orthodb.org/?gene=A0A8M2BE81", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FFH0", "url": "https://www.orthodb.org/?gene=E7FFH0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24136", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24136", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24136:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24136:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13857", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13857", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_684802", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_684802", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BE81", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BE81", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BE81-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BE81-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FFH0", "url": "https://www.uniprot.org/uniprotkb/E7FFH0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FFH0-1", "url": "https://www.uniprot.org/uniprotkb/E7FFH0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091118-116", "url": "https://zfin.org/ZDB-GENE-091118-116", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEFEITRTRPSLFGDIAHGLGFWTDRSAVHEAAAQGRVVQLRKLIENGASVNIVAVDSITPLHEACIQGHTQCVKLLLDAGAHVDARNIDGSTPLCDACAAGSLECVKLLLEHGATVNPPLFTFSPLHEACMGGNSKCVQLMIDEGALMEAHDCHFGTPLHVACARQHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNLELIELLVEFGGNIFARDNLGKKPIQYTRSSSASALCLEFYESTPLSLQQLCRISLRNALGKRALGVFTQLGLPNRIIWFLSYLPAPPMELLQS", "length": 294, "header": "tr|E7FFH0-1|E7FFH0_DANRE Isoform 1 of Ankyrin repeat and SOCS box protein 13 isoform X1 OS=Danio rerio OX=7955 GN=asb13b PE=3 SV=1 CANONICAL=E7FFH0-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BE81-1", "url": "https://www.uniprot.org/uniprotkb/E7FFH0/entry#A0A8M2BE81-1", "sequence": { "sequence": "MEFEITRTRPSLFGDIAHGLGFWTDRSAVHEAAAQGRVVQLRKLIENGASVNIVAVDSITPLHEACIQGHTQCVKLLLDAGAHVDARNIDGSTPLCDACAAGSLECVKLLLEHGATVNPPLFTFSPLHEACMGGANVNAAKLHETALHHAAKVKNLELIELLVEFGGNIFARDNLGKKPIQYTRSSSASALCLEFYESTPLSLQQLCRISLRNALGKRALGVFTQLGLPNRIIWFLSYLPAPPMELLQS", "length": 249, "header": "tr|A0A8M2BE81-1|E7FFH0_DANRE Computationally mapped isoform of Ankyrin repeat and SOCS box protein 13 isoform X1 OS=Danio rerio OX=7955 GN=asb13b PE=3 SV=1 CANONICAL=E7FFH0-1" }, "locus": {} }, { "isoform_ac": "E7FFH0-1", "url": "https://www.uniprot.org/uniprotkb/E7FFH0/entry#E7FFH0-1", "sequence": { "sequence": "MEFEITRTRPSLFGDIAHGLGFWTDRSAVHEAAAQGRVVQLRKLIENGASVNIVAVDSITPLHEACIQGHTQCVKLLLDAGAHVDARNIDGSTPLCDACAAGSLECVKLLLEHGATVNPPLFTFSPLHEACMGGNSKCVQLMIDEGALMEAHDCHFGTPLHVACARQHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNLELIELLVEFGGNIFARDNLGKKPIQYTRSSSASALCLEFYESTPLSLQQLCRISLRNALGKRALGVFTQLGLPNRIIWFLSYLPAPPMELLQS", "length": 294, "header": "tr|E7FFH0-1|E7FFH0_DANRE Isoform 1 of Ankyrin repeat and SOCS box protein 13 isoform X1 OS=Danio rerio OX=7955 GN=asb13b PE=3 SV=1 CANONICAL=E7FFH0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:556808", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556808", "resource": "KEGG Pathway" }, { "id": "R-DRE-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-DRE-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AIT5-1", "protein_name": "Ankyrin repeat and SOCS box containing 13", "gene_name": "ASB13", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEPRTADGCFLGDVGFWVERTPVHEAAQRGETRQLQQLIESGACVNQVTVDSITPLHAASLQGQAQCVQLLLAAGAQVDARNIDGSTPLCDACASGSVECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEMLVQFGGDIYARDNRGRKPSDYARSSSAPARCLEHYEKTPLTLSQLCRVSLRRATGVRGLEKIAKLNIPARLIEYLSYN", "length": 278 }, "evidence": [ { "id": "E7FFH0", "url": "https://omabrowser.org/oma/group/E7FFH0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XZ64-1", "protein_name": "Ankyrin repeat and SOCS box containing 13", "gene_name": "ASB13", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MCTFAERPLALTLHTQDQTKKKSELIPLYKPLNLPMERPEARLYAPCCVCDVLFPRGFWVDRTPVHEAARQGEILQLQQLIESGACVNAVTYDSITPLHEASLRGQTQCVKLLLAAGAQVDARNIDGSTPLCDACASGSIECVKVLLSHGAKVNPPLYTASPLHEACMNGSSDCVQLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKLLLKAGANVNAAKLHETALHHAAKVKNVDLVEMLIEFGGNIYARDNRGKKPSDYTLRSSPTAKCFEYYEKTPLSLSQLCRVTVRKAAGQRALEKIAKLNIPQRLIQYLSYN", "length": 320 }, "evidence": [ { "id": "E7FFH0", "url": "https://omabrowser.org/oma/group/E7FFH0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZEJ6-1", "protein_name": "Ankyrin repeat and SOCS box-containing 13", "gene_name": "Asb13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEPRAGDRCFLGDVGFWVERTPVHEAAQRGESLQLQQLINSGACVNQVTVDSITPLHAASLQGQAQCVQLLLAAGAQVDARNIDGSTPLCDACASGNVECVKLLLSYGAKVNPPLYTASPLHEACMSGNSDCVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIVMLIEFGGNIYARDNRGKKPSDYTWSSSAPAKCFEYYEKTPLTLSQLCRVTLRKATGVRGLEKVAKLNIPPRLIDYLSYN", "length": 278 }, "evidence": [ { "id": "MGI:2145525", "url": "https://alliancegenome.org/gene/MGI:2145525#orthology", "database": "AGR" }, { "id": "HGNC:19765", "url": "https://alliancegenome.org/gene/HGNC:19765#orthology", "database": "AGR" }, { "id": "E7FFH0", "url": "https://omabrowser.org/oma/group/E7FFH0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BJ12-1", "protein_name": "Ankyrin repeat and SOCS box containing 13", "gene_name": "ASB13", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MEPRASDSSFLGDVGFWVERTPVHEAAQRGETRQLQQLIESGACVNQVTVDSITPLHAASLQGQVQCVQLLLAAGAQVDARNIDGSTPLCDACASGSVECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEMLIQFGGNIYARDNRGRKPSDYTWASSAPARCLEHYEKTPLSLSQLCRVSLRRAAGVRGLEKIARLDIPPRLIDFLSYN", "length": 278 }, "evidence": [ { "id": "E7FFH0", "url": "https://omabrowser.org/oma/group/E7FFH0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3GR75-1", "protein_name": "Ankyrin repeat and SOCS box protein 13", "gene_name": "Asb13", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MEPRAGDGCFLGDVGFWVERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQAQCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKPSDYTWSSSAPAKCFEYYEKTPLTLSQLCRVSLRKATGVRGLEKVAKLNIPPRLIDYLSYN", "length": 278 }, "evidence": [ { "id": "E7FFH0", "url": "https://omabrowser.org/oma/group/E7FFH0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1LX92-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "asb13a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEVETARPYFFGDIGFWAERTEVHKAAYEGEVSVLQDLISSGASVNIVAVDSITPLHEAAARGQTQCVRLLLDAGAQVDARNVDGSTPLCEACSIGNFECVRLLLDYGAKVNPTLTSRTTSPLHEACMGGNADCVRLVIAKGASLEAYDLYHGTPLHVACANRRLECVKVLLNAGVHVNATRLHETPLHHAARTNNVNMIEMLVEFGANIYARDKYDRKPVDYTRPNTPSAHCLQLYESSPLSLQQICRITLRTVLGTNAEDVVGKLDIPNRIISYLLYR", "length": 280 }, "evidence": [ { "id": "MGI:2145525", "url": "https://alliancegenome.org/gene/MGI:2145525#orthology", "database": "AGR" }, { "id": "HGNC:19765", "url": "https://alliancegenome.org/gene/HGNC:19765#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8VBX0-1", "protein_name": "Ankyrin repeat and SOCS box protein 13", "gene_name": "Asb13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEPRAGDGCFLGDVGFWVERTPVHEAAQRGESLQLQQLIDSGACVNQVTVDSITPLHAASLQGQAQCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKPSDYTWSSSAPAKCFEYYEKTPLSLSQLCRVSLRKATGVRGLEKVAKLNIPPRLIDYLSYN", "length": 278 }, "evidence": [ { "id": "MGI:2145525", "url": "https://alliancegenome.org/gene/MGI:2145525#orthology", "database": "AGR" }, { "id": "HGNC:19765", "url": "https://alliancegenome.org/gene/HGNC:19765#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091118-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-116#orthology", "database": "AGR" }, { "id": "E7FFH0", "url": "https://omabrowser.org/oma/group/E7FFH0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WXK3-1", "protein_name": "Ankyrin repeat and SOCS box protein 13", "gene_name": "ASB13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPRAADGCFLGDVGFWVERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVLLNAGANVNAAKLHETALHHAAKVKNVDLIEMLIEFGGNIYARDNRGKKPSDYTWSSSAPAKCFEYYEKTPLTLSQLCRVNLRKATGVRGLEKIAKLNIPPRLIDYLSYN", "length": 278 }, "evidence": [ { "id": "MGI:2145525", "url": "https://alliancegenome.org/gene/MGI:2145525#orthology", "database": "AGR" }, { "id": "HGNC:19765", "url": "https://alliancegenome.org/gene/HGNC:19765#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091118-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091118-116#orthology", "database": "AGR" }, { "id": "E7FFH0", "url": "https://omabrowser.org/oma/group/E7FFH0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "E7FFH0", "url": "https://www.uniprot.org/uniprotkb/E7FFH0" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "E7FFH0", "url": "https://www.uniprot.org/uniprotkb/E7FFH0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FFH0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FFH0" }, { "id": "PS50225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SOCS box", "eco_id": "ECO_0000259", "start_pos": 235, "end_pos": 287, "start_aa": "Ala", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1Q6B0-1", "uniprot_ac": "F1Q6B0", "uniprot_id": "F1Q6B0_DANRE", "mass": { "chemical_mass": 107784.0, "monoisotopic_mass": 107784.0 }, "refseq": { "ac": "XP_001344807", "name": "uncharacterized protein si:dkey-183p4.10 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344807" }, "gene_names": [ { "name": "si:dkey-183p4.10", "type": "recommended", "evidence": [ { "id": "F1Q6B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q6B0" } ] }, { "name": "si:dkey-183p4.10", "type": "synonym", "evidence": [ { "id": "XP_001344807", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344807" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkey-183p4.10 isoform X1", "type": "synonym", "evidence": [ { "id": "F1Q6B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q6B0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkey-183p4.10 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001344807", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344807" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001344807.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001344807", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344807" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q6B0", "url": "https://www.uniprot.org/uniprotkb/F1Q6B0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-183p4.10", "url": "https://www.uniprot.org/uniprotkb/F1Q6B0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-337", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-337", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077907", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077907", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100005882", "url": "https://www.ncbi.nlm.nih.gov/gene/100005882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:100005882", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005882", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LISYICM", "url": "https://omabrowser.org/oma/group/LISYICM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BEK3", "url": "https://www.orthodb.org/?gene=A0A8M2BEK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1Q6B0", "url": "https://www.orthodb.org/?gene=F1Q6B0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_001344807", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344807", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BEK3", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BEK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BEK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BEK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q6B0", "url": "https://www.uniprot.org/uniprotkb/F1Q6B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q6B0-1", "url": "https://www.uniprot.org/uniprotkb/F1Q6B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-337", "url": "https://zfin.org/ZDB-GENE-081104-337", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDQNIADFLTDAFPEPNFEHLHFDDDTAMAHSVDVSQDMPDMEDNEYSNKESSESDSEVDDDTTAENNINTSQNAPDMEDDNNSNQTSSESDYEVDFESKNSDRLHSDDDTTAANNINTPQNEADIENDNNSDQESSESDSEVDFESKNIERLHCDDETTTEHSINTPQNAADMQDNEKNNREYSGTEFDLDLECKNREEEIKNCPENNSDFSLDEQNMKPGSTLGGSLDDNNSDENKTPTQDQQLSLHDEESREDGFEDIHQAENDNMQKMALQKEPLLDLDTMRSHKKSTSHLLSHQMVDESENESSTSEEDTVELKSTKDDNKLYCLGSTLQDWPVESIEVQSGDELKEFTEDDLEREEEGLAEYPSDLSRSDSGDSGEGQTMDTKLDDGLGWSGEMKMEELTMSYQAVTLRKDAEDVSVDHADVPTCVKNEDLNETTTSRKSDDTLFRIKQVSFRDDHYSSEISIAGESPDFEIAANVQSKSSASYKNVQPEYDGDISCDGDYCKIQDEKPDLPFQTEKNKPTLLKQDHTFIEDFSTDVELKVGDVLVTDSEKCDVSSSSIHPGSKKGGLPERHSTETCSSKLYSSEACKSKDNSEDITVLLPGTFWSVMDEDNLKFDEYDWDINGEEALCDEEDSLLEDLENEGEGSERDWEKEKERIKAFNKYYNTVEGEENKDRTPLVTFCLEPKYSLYEEESDSSEEDLNTKCCMYEQHPSESSLFQDQSNNDNSRQASDTLENISALLRDEDNVMFDEYDYGIGEEEFYKTNSSKTILDDEDDFLEKLKIEIEREMQQERTEALNKFYEESGQEKHKVTDRSQKGLYGLHQDSQNEEDNESSEQESYTEEDTSRALKIKDQSDSDEPHERRLYTGRPKVLLKGLQRADKQLKEPRKRNKCVFLLRSVFALSLVTVVGLLSYSWATDNMDLLNTHVSSVFNMIQNRQ", "length": 945, "header": "tr|F1Q6B0-1|F1Q6B0_DANRE Isoform 1 of Uncharacterized protein si:dkey-183p4.10 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-183p4.10 PE=4 SV=1 CANONICAL=F1Q6B0-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BEK3-1", "url": "https://www.uniprot.org/uniprotkb/F1Q6B0/entry#A0A8M2BEK3-1", "sequence": { "sequence": "MDQNIADFLTDAFPEPNFEHLHFDDDTAMAHSVDVSQDMPDMEDNEYSNKESSESDSEVDDDTTAENNINTSQNAPDMEDDNNSNQTSSESDYEVDFESKNSDRLHSDDDTTAANNINTPQNEADIENDNNSDQESSESDSEVDFESKNIERLHCDDETTTEHSINTPQNAADMQDNEKNNREYSGTEFDLDLECKNREEEIKNCPENNSDFSLDEQNMKPGSTLGGSLDDNNSDENKTPTQDQQLSLHDEESREDGFEDIHQAENDNMQKMALQKEPLLDLDTMRSHKKSTSHLLSHQMVDESENESSTSEEDTVELKSTKDDNKLYCLGSTLQDWPVESIEVQSGDELKEFTEDDLEREEEGLAEYPSDLSRSDSGDSGEGQTMDTKLDDGLGWSGEMKMEELTMSYQAVTLRKDAEDVSVDHADVPTCVKNEDLNETTTSRKSDDTLFRIKQVSFRDDHYSSEISIAGESPDFEIAANVQSKSSASYKNVQPEYDGDISCDGDYCKIQDEKPDLPFQTEKNKPTLLKQDHTFIEDFSTDVELKVGDVLVTDSEKCDVSSSSIHPGSKKGGLPERHSTETCSSKLYSSEACKSKDNSEDITVLLPGTFWSVMDEDNLKFDEYDWDINGEEALCDEEDSLLEDLENEGEGSERDWEKEKERIKAFNKYYNTVEGEENKDRTPLVTFCLEPKYSLYEEESDSEEDLNTKCCMYEQHPSESSLFQDQSNNDNSRQASDTLENISALLRDEDNVMFDEYDYGIGEEEFYKTNSSKTILDDEDDFLEKLKIEIEREMQQERTEALNKFYEESGQEKHKVTDRSQKGLYGLHQDSQNEEDNESSEQESYTEEDTSRALKIKDQSDSDEPHERRLYTGRPKVLLKGLQRADKQLKEPRKRNKCVFLLRSVFALSLVTVVGLLSYSWATDNMDLLNTHVSSVFNMIQNRQ", "length": 944, "header": "tr|A0A8M2BEK3-1|F1Q6B0_DANRE Computationally mapped isoform of Uncharacterized protein si:dkey-183p4.10 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-183p4.10 PE=4 SV=1 CANONICAL=F1Q6B0-1" }, "locus": {} }, { "isoform_ac": "F1Q6B0-1", "url": "https://www.uniprot.org/uniprotkb/F1Q6B0/entry#F1Q6B0-1", "sequence": { "sequence": "MDQNIADFLTDAFPEPNFEHLHFDDDTAMAHSVDVSQDMPDMEDNEYSNKESSESDSEVDDDTTAENNINTSQNAPDMEDDNNSNQTSSESDYEVDFESKNSDRLHSDDDTTAANNINTPQNEADIENDNNSDQESSESDSEVDFESKNIERLHCDDETTTEHSINTPQNAADMQDNEKNNREYSGTEFDLDLECKNREEEIKNCPENNSDFSLDEQNMKPGSTLGGSLDDNNSDENKTPTQDQQLSLHDEESREDGFEDIHQAENDNMQKMALQKEPLLDLDTMRSHKKSTSHLLSHQMVDESENESSTSEEDTVELKSTKDDNKLYCLGSTLQDWPVESIEVQSGDELKEFTEDDLEREEEGLAEYPSDLSRSDSGDSGEGQTMDTKLDDGLGWSGEMKMEELTMSYQAVTLRKDAEDVSVDHADVPTCVKNEDLNETTTSRKSDDTLFRIKQVSFRDDHYSSEISIAGESPDFEIAANVQSKSSASYKNVQPEYDGDISCDGDYCKIQDEKPDLPFQTEKNKPTLLKQDHTFIEDFSTDVELKVGDVLVTDSEKCDVSSSSIHPGSKKGGLPERHSTETCSSKLYSSEACKSKDNSEDITVLLPGTFWSVMDEDNLKFDEYDWDINGEEALCDEEDSLLEDLENEGEGSERDWEKEKERIKAFNKYYNTVEGEENKDRTPLVTFCLEPKYSLYEEESDSSEEDLNTKCCMYEQHPSESSLFQDQSNNDNSRQASDTLENISALLRDEDNVMFDEYDYGIGEEEFYKTNSSKTILDDEDDFLEKLKIEIEREMQQERTEALNKFYEESGQEKHKVTDRSQKGLYGLHQDSQNEEDNESSEQESYTEEDTSRALKIKDQSDSDEPHERRLYTGRPKVLLKGLQRADKQLKEPRKRNKCVFLLRSVFALSLVTVVGLLSYSWATDNMDLLNTHVSSVFNMIQNRQ", "length": 945, "header": "tr|F1Q6B0-1|F1Q6B0_DANRE Isoform 1 of Uncharacterized protein si:dkey-183p4.10 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-183p4.10 PE=4 SV=1 CANONICAL=F1Q6B0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100005882", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005882", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 130, "end_pos": 132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 237, "end_pos": 239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 306, "end_pos": 308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 438, "end_pos": 440, "annotation": "n_glycosylation_sequon" }, { "start_pos": 70, "end_pos": 72, "annotation": "n_glycosylation_sequon" }, { "start_pos": 742, "end_pos": 744, "annotation": "n_glycosylation_sequon" }, { "start_pos": 771, "end_pos": 773, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" }, { "start_pos": 838, "end_pos": 840, "annotation": "n_glycosylation_sequon" }, { "start_pos": 85, "end_pos": 87, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 130, "end_pos": 132 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 232, "end_pos": 234 }, { "start_pos": 237, "end_pos": 239 }, { "start_pos": 306, "end_pos": 308 }, { "start_pos": 438, "end_pos": 440 }, { "start_pos": 70, "end_pos": 72 }, { "start_pos": 742, "end_pos": 744 }, { "start_pos": 771, "end_pos": 773 }, { "start_pos": 82, "end_pos": 84 }, { "start_pos": 838, "end_pos": 840 }, { "start_pos": 85, "end_pos": 87 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E9QEN8-1", "uniprot_ac": "E9QEN8", "uniprot_id": "E9QEN8_DANRE", "mass": { "chemical_mass": 63782.0, "monoisotopic_mass": 63782.0 }, "refseq": { "ac": "XP_009302187", "name": "protein ENL isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302187" }, "gene_names": [ { "name": "mllt1a", "type": "recommended", "evidence": [ { "id": "E9QEN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QEN8" } ] }, { "name": "mllt1a", "type": "synonym", "evidence": [ { "id": "XP_009302187", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302187" } ] } ], "protein_names": [ { "name": "Protein ENL isoform X1", "type": "synonym", "evidence": [ { "id": "E9QEN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QEN8/entry#names_and_taxonomy" } ] }, { "name": "protein ENL isoform X1", "type": "synonym", "evidence": [ { "id": "XP_009302187", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302187" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009302187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302187" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QEN8", "url": "https://www.uniprot.org/uniprotkb/E9QEN8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mllt1a", "url": "https://www.uniprot.org/uniprotkb/E9QEN8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081105-45", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-45", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000043185", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000043185", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16906", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16906", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "565484", "url": "https://www.ncbi.nlm.nih.gov/gene/565484", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR038704", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038704", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040930", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040930", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052790", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052790", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055129", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055129", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565484", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565484", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M2BEY9", "url": "https://www.orthodb.org/?gene=A0A8M2BEY9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3BBR5", "url": "https://www.orthodb.org/?gene=A0A8M3BBR5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7T7S1", "url": "https://www.orthodb.org/?gene=A0A8N7T7S1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E9QEN8", "url": "https://www.orthodb.org/?gene=E9QEN8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47827", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47827", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47827:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47827:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03366", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03366", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17793", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17793", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-674695", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-674695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-75955", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-75955", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_009302187", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302187", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BEY9", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BEY9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BEY9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BEY9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3BBR5", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BBR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3BBR5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BBR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7T7S1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T7S1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7T7S1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7T7S1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QEN8", "url": "https://www.uniprot.org/uniprotkb/E9QEN8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QEN8-1", "url": "https://www.uniprot.org/uniprotkb/E9QEN8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081105-45", "url": "https://zfin.org/ZDB-GENE-081105-45", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MENQCTVQVKLELGHRAQLRKKVTSEGFTHDWMVFVRGPEGSDIQHFVDKVVFRLHESFPKPKRVCKEPQYKVEESGYAGFLMPIEVYFKNKEEPKKVCFNYDLFLNLEGNPPVNHLRCEKLTFNNPTRDFRRKLVKAGGLIVVPEGAEVVPRPSPDYPMLPTIPLSAFSDPKKSKTSQGSKEPSKEGSKVSKSHKMAKEHRERPRKDSESKATSKGDSERDGTSKSSRDPSSSSSSSSKKTEIKVKDDNKVLPKAAFKEPKLTLKESKMESMSPKGGGAGAAGGGGGAADGKAPSKRPSNAESPKPSVKKPKKGSSEGSKCSGSGGFTGTSPRTTSSSNTSSGYAEKKTSKEKGRWAKGKSEAQGVKETKKPPESDDSNSDDEASSKSEQSAPSSPSNSSSSSESSSDSDFEPEQKQGQGPLRSMVEDLQSEESDDDDSSSDEETPVKNNLPSRDSRLSLDSESDCSDGPQRPSRDAPPQPPKHSSNNKVSGRKSPDPCLRQEKVLKKGYDKVGRAYTDELVDLHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDESTVRKLQSYLEATTT", "length": 582, "header": "tr|E9QEN8-1|E9QEN8_DANRE Isoform 1 of Protein ENL isoform X1 OS=Danio rerio OX=7955 GN=mllt1a PE=4 SV=1 CANONICAL=E9QEN8-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BEY9-1", "url": "https://www.uniprot.org/uniprotkb/E9QEN8/entry#A0A8M2BEY9-1", "sequence": { "sequence": "MENQCTVQVKLELGHRAQLRKKVTSEGFTHDWMVFVRGPEGSDIQHFVDKVVFRLHESFPKPKRVCKEPQYKVEESGYAGFLMPIEVYFKNKEEPKKVCFNYDLFLNLEGNPPVNHLRCEKLTFNNPTRDFRRKLVKAGGLIVVPEGAEVVPRPSPDYPMLPTIPLSAFSDPKKSKTSQGSKEPSKEGSKVSKSHKMAKEHRERPRKDSESKATSKGDSERDGTSKSSRDPSSSSSSSSKKTEIKVKDDNKVLPKAAFKEPKLTLKESKMESMSPKGGGAGAAGGGGGAADGKAPSKRPSNAESPKPSVKKPKKGSSEGSKCSGSGGFTGTSPRTTSSSNTSSGYAEKKTSKEKGRWAKGKSEAQGVKETKKPPESDDSNSDDEASSKSESAPSSPSNSSSSSESSSDSDFEPEQKQGQGPLRSMVEDLQSEESDDDDSSSDEETPVKNNLPSRDSRLSLDSESDCSDGPQRPSRDAPPQPPKHSSNNKVSGRKSPDPCLRQEKVLKKGYDKAYTDELVDLHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDESTVRKLQSYLEATTT", "length": 578, "header": "tr|A0A8M2BEY9-1|E9QEN8_DANRE Computationally mapped isoform of Protein ENL isoform X1 OS=Danio rerio OX=7955 GN=mllt1a PE=4 SV=1 CANONICAL=E9QEN8-1" }, "locus": {} }, { "isoform_ac": "A0A8M3BBR5-1", "url": "https://www.uniprot.org/uniprotkb/E9QEN8/entry#A0A8M3BBR5-1", "sequence": { "sequence": "MENQCTVQVKLELGHRAQLRKKVTSEGFTHDWMVFVRGPEGSDIQHFVDKVVFRLHESFPKPKRVCKEPQYKVEESGYAGFLMPIEVYFKNKEEPKKVCFNYDLFLNLEGNPPVNHLRCEKLTFNNPTRDFRRKLVKAGGLIVVPEGAEVVPRPSPDYPMLPTIPLSAFSDPKKSKTSQGSKEPSKEGSKVSKSHKMAKEHRERPRKDSESKATSKGDSERDGTSKSSRDPSSSSSSSSKKTEIKVKDDNKVLPKAAFKEPKLTLKESKMESMSPKGGGAGAAGGGGGAADGKAPSKRPSNAESPKPSVKKPKKGSSEGSKCSGSGGFTGTSPRTTSSSNTSSGYAEKKTSKEKGRWAKGKSEAQGVKETKKPPESDDSNSDDEASSKSESAPSSPSNSSSSSESSSDSDFEPEQKQGQGPLRSMVEDLQSEESDDDDSSSDEETPVKNNLPSRDSRLSLDSESDCSDGPQRPSRDAPPQPPKHSSNNKVSGRKSPDPCLRQEKVLKKGYDKVGRAYTDELVDLHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDESTVRKLQSYLEATTT", "length": 581, "header": "tr|A0A8M3BBR5-1|E9QEN8_DANRE Computationally mapped isoform of Protein ENL isoform X1 OS=Danio rerio OX=7955 GN=mllt1a PE=4 SV=1 CANONICAL=E9QEN8-1" }, "locus": {} }, { "isoform_ac": "A0A8N7T7S1-1", "url": "https://www.uniprot.org/uniprotkb/E9QEN8/entry#A0A8N7T7S1-1", "sequence": { "sequence": "MENQCTVQVKLELGHRAQLRKKVTSEGFTHDWMVFVRGPEGSDIQHFVDKVVFRLHESFPKPKRVCKEPQYKVEESGYAGFLMPIEVYFKNKEEPKKVCFNYDLFLNLEGNPPVNHLRCEKLTFNNPTRDFRRKLVKAGGLIVVPEGAEVVPRPSPDYPMLPTIPLSAFSDPKKSKTSQGSKEPSKEGSKVSKSHKMAKEHRERPRKDSESKATSKGDSERDGTSKSSRDPSSSSSSSSKKTEIKVKDDNKVLPKAAFKEPKLTLKESKMESMSPKGGGAGAAGGGGGAADGKAPSKRPSNAESPKPSVKKPKKGSSEGSKCSGSGGFTGTSPRTTSSSNTSSGYAEKKTSKEKGRWAKGKSEAQGVKETKKPPESDDSNSDDEASSKSEQSAPSSPSNSSSSSESSSDSDFEPEQKQGQGPLRSMVEDLQSEESDDDDSSSDEETPVKNNLPSRDSRLSLDSESDCSDGPQRPSRDAPPQPPKHSSNNKVSGRKSPDPCLRQEKVLKKGYDKAYTDELVDLHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDESTVRKLQSYLEATTT", "length": 579, "header": "tr|A0A8N7T7S1-1|E9QEN8_DANRE Computationally mapped isoform of Protein ENL isoform X1 OS=Danio rerio OX=7955 GN=mllt1a PE=4 SV=1 CANONICAL=E9QEN8-1" }, "locus": {} }, { "isoform_ac": "E9QEN8-1", "url": "https://www.uniprot.org/uniprotkb/E9QEN8/entry#E9QEN8-1", "sequence": { "sequence": "MENQCTVQVKLELGHRAQLRKKVTSEGFTHDWMVFVRGPEGSDIQHFVDKVVFRLHESFPKPKRVCKEPQYKVEESGYAGFLMPIEVYFKNKEEPKKVCFNYDLFLNLEGNPPVNHLRCEKLTFNNPTRDFRRKLVKAGGLIVVPEGAEVVPRPSPDYPMLPTIPLSAFSDPKKSKTSQGSKEPSKEGSKVSKSHKMAKEHRERPRKDSESKATSKGDSERDGTSKSSRDPSSSSSSSSKKTEIKVKDDNKVLPKAAFKEPKLTLKESKMESMSPKGGGAGAAGGGGGAADGKAPSKRPSNAESPKPSVKKPKKGSSEGSKCSGSGGFTGTSPRTTSSSNTSSGYAEKKTSKEKGRWAKGKSEAQGVKETKKPPESDDSNSDDEASSKSEQSAPSSPSNSSSSSESSSDSDFEPEQKQGQGPLRSMVEDLQSEESDDDDSSSDEETPVKNNLPSRDSRLSLDSESDCSDGPQRPSRDAPPQPPKHSSNNKVSGRKSPDPCLRQEKVLKKGYDKVGRAYTDELVDLHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDESTVRKLQSYLEATTT", "length": 582, "header": "tr|E9QEN8-1|E9QEN8_DANRE Isoform 1 of Protein ENL isoform X1 OS=Danio rerio OX=7955 GN=mllt1a PE=4 SV=1 CANONICAL=E9QEN8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:565484", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565484", "resource": "KEGG Pathway" }, { "id": "R-DRE-674695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-674695", "resource": "Reactome", "description": "RNA Polymerase II Pre-transcription Events" }, { "id": "R-DRE-75955", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-75955", "resource": "Reactome", "description": "RNA Polymerase II Transcription Elongation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KG69-1", "protein_name": "ENL/AF9-related, isoform B", "gene_name": "ear", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAVKVQFEIGHTSKLRSKKTPHPQAFTHDWEIYVQGVNKADISAFVEKVVFVLHESFPKPKRVVKEPPYAIQESGYAGFLLPVEIYFRNRDEPKRIVYQYDLVLQSTGPPQHHVEVKTHIFEAPSEEFRTKLMRGGGVPVFGANIGAGSLARTLSPSVGSGETAHSNEMSGVKAKGVPGTISMNSDLNTGKKHKSRSEDPGKSNAFSALFGPPITKTSVTANNMAQVPVSKHSPEAKSAAVGGKGVFHEGREKASKDRDKSSGGDKPREKDKKDRHGRDKDRKSSKSGDGKHERDKEKSKKDKSRDKEREREQGSGNTTSANALTVATSVGTAGGLVKHTASPKPGKPNEMGAPSPKKTANDSAAGAVAPTSRSKERDEHKSVKSESKDKERSSSKKSKKDKKDKDKQRDESKDKRMPKDERPGQSDSPASGNLQSAHLQQQSQVASTGKATPTSVGSNSSSSMVSNIGKQKEEATGKHSEKAAESKGDKSTSNGNATDTKKSHKHKKKEKSKDKEKERNDRDKDKDKERDKDKLKEREKDKQHVTGSEKSSTVDPSPKLEGASPATEGGAPDKTPVSASASSGSKKEKHKKSKEKSSGKDEKRQREAVDKQADTKHTGKSQQSQSGQSKTPSNLDLSDMDSAQSAPDLAATNALAAAAAATLQHSDSSNSSFPDLPARSSSQQKPTKGNTGSGKETKSTVKEHKGKSKQNDKTLEKNTDKTEKPDKTPDPKVDKSEKSEKEDKKRNRRSSQSSNSGSGAGVTGAFIEPPVKASKKEQGKAAGEKSKSPSLRPPRETNSTGTGGGTPNAGAGFLAPPSSSPSNNHSAAVAASLNNNNNNNNNNTNSNSSHSPGEMTTPGQLQLPTEYLSELQELHHKIMTLQDNEELQHVVEMIAATGCYEITHKTFDFDLCKLDRGTVQRLQEFLATSVSXHSLTSATGPALYS", "length": 945 }, "evidence": [ { "id": "HGNC:7134", "url": "https://alliancegenome.org/gene/HGNC:7134#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8M2BIJ1-1", "protein_name": "MLLT1 super elongation complex subunit b isoform X1", "gene_name": "mllt1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MENMCTVQVKLELGHRAQLRKKVTTEGFTHDWMVFVRGPEACDIQHFVERVVFRLHDSFPKPKRVCKEPPYKVEESGYAGFLMPIEVYFKNKEEPKKVCFNYDLFLNLEGNPPVNHLRCEKLTFNNPTHEFRRKLVKAGGVFFSSQAIVVPEGAEMMPRPSPDYPMLPTIPLSAFSDPKKIKSSHVVKESSKDGGSGSSKSLKAHKATKEHQERTRKDSESKATSRESDREGKSSRDLSSSSFSKKSTDGRGKDDVKTVPKAAFKEPKLTVRESKMDGMSPKGGGGVTVGVDTRTPGKRPSSANESPKLSTKKQKRIGSEGMKGGGYSSSSPRITSTTPSNYPEKKTTKDKGHWTKIKTEVAEVKRQPDSDESNSEDEASSKSEQSAPSSPSSSSSSSSSDSDFEPSQKQGQGTLRSMVEDMHSEGSDDDSSSEVETPMKTTPFNHDSRLSMDSESDGNEESRPPSQEAPSPSLKLSSANLKMLGKKSPDSCNREKIIKRGYDKVGTAYTEELMDLHRRLMALRERNILQQIVNLIEKTGHFNITNTTFDFDLFSLDESTVRKLQSYLEATST", "length": 573 }, "evidence": [ { "id": "HGNC:7134", "url": "https://alliancegenome.org/gene/HGNC:7134#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M0R462-1", "protein_name": "MLLT1, super elongation complex subunit", "gene_name": "Mllt1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDNQCTVQVKLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVIFRLHDSFPKPKRVCKEPPYKVEESGYAGFIMLIEVYFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRCKLLMAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKNKPSHGSKDANKESGKASKPHKVAREHRERPRKDSESRSCSKEPEREPKSAKDAARKLPKEEKAPVPKAAFKEPKMALKETKLESLSPKGVSQPPTLPKASSKRPAATDSPKPSAKKPKKSGSKGARRAPGTSPRASSFPDKKVARDKSSKGDKGKMESEPREAKRTLQAEDSNSEDEASFRSESAQSSPAHASSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEGSDEDDSSSGEESTVKTNPGRESRLSFSDSESDNSADSCLPGREPLPPQKPPPPSSKVTGRRSPEPCSKPEKILKKATYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDESTVRKLQSCLEAVAT", "length": 547 }, "evidence": [ { "id": "HGNC:7134", "url": "https://alliancegenome.org/gene/HGNC:7134#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P35189-1", "protein_name": "Transcription initiation factor TFIID subunit 14", "gene_name": "TAF14", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MVATVKRTIRIKTQQHILPEVPPVENFPVRQWSIEIVLLDDEGKEIPATIFDKVIYHLHPTFANPNRTFTDPPFRIEEQGWGGFPLDISVFLLEKAGERKIPHDLNFLQESYEVEHVIQIPLNKPLLTEELAKSGSTEETTANTGTIGKRRTTTNTTAEPKAKRAKTGSASTVKGSVDLEKLAFGLTKLNEDDLVGVVQMVTDNKTPEMNVTNNVEEGEFIIDLYSLPEGLLKSLWDYVKKNTE", "length": 244 }, "evidence": [ { "id": "HGNC:7134", "url": "https://alliancegenome.org/gene/HGNC:7134#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q03111-1", "protein_name": "Protein ENL", "gene_name": "MLLT1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDNQCTVQVRLELGHRAQLRKKPTTEGFTHDWMVFVRGPEQCDIQHFVEKVVFWLHDSFPKPRRVCKEPPYKVEESGYAGFIMPIEVHFKNKEEPRKVCFTYDLFLNLEGNPPVNHLRCEKLTFNNPTTEFRYKLLRAGGVMVMPEGADTVSRPSPDYPMLPTIPLSAFSDPKKTKPSHGSKDANKESSKTSKPHKVTKEHRERPRKDSESKSSSKELEREQAKSSKDTSRKLGEGRLPKEEKAPPPKAAFKEPKMALKETKLESTSPKGGPPPPPPPPPRASSKRPATADSPKPSAKKQKKSSSKGSRSAPGTSPRTSSSSSFSDKKPAKDKSSTRGEKVKAESEPREAKKALEVEESNSEDEASFKSESAQSSPSNSSSSSDSSSDSDFEPSQNHSQGPLRSMVEDLQSEESDEDDSSSGEEAAGKTNPGRDSRLSFSDSESDNSADSSLPSREPPPPQKPPPPNSKVSGRRSPESCSKPEKILKKGTYDKAYTDELVELHRRLMALRERNVLQQIVNLIEETGHFNVTNTTFDFDLFSLDETTVRKLQSCLEAVAT", "length": 559 }, "evidence": [ { "id": "HGNC:7134", "url": "https://alliancegenome.org/gene/HGNC:7134#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081105-45", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-45#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E9QEN8", "url": "https://www.uniprot.org/uniprotkb/E9QEN8" } ], "pmid": "" }, { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "E9QEN8", "url": "https://www.uniprot.org/uniprotkb/E9QEN8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "chromatin binding", "id": "GO:0003682", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003682", "evidence": [ { "database": "UniProtKB", "id": "E9QEN8", "url": "https://www.uniprot.org/uniprotkb/E9QEN8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E9QEN8", "url": "https://www.uniprot.org/uniprotkb/E9QEN8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 555, "end_pos": 557, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E9QEN8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QEN8" }, { "id": "PS51037", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51037" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "YEATS", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 138, "start_aa": "Met", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 340, "end_pos": 342 }, { "start_pos": 399, "end_pos": 401 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 555, "end_pos": 557 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E9QFI8-1", "uniprot_ac": "E9QFI8", "uniprot_id": "E9QFI8_DANRE", "mass": { "chemical_mass": 19058.0, "monoisotopic_mass": 19058.0 }, "refseq": { "ac": "XP_005167838", "name": "uncharacterized protein CFAP97D2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167838" }, "gene_names": [ { "name": "cfap97d2", "type": 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This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. 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"categories": [ "Protein Classification" ] }, { "id": "PTHR33768:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33768:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13879", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13879", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005167838", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167838", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BF76", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BF76", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BF76-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BF76-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QFI8", "url": "https://www.uniprot.org/uniprotkb/E9QFI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QFI8-1", "url": "https://www.uniprot.org/uniprotkb/E9QFI8-1", "database": 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OS=Danio rerio OX=7955 GN=cfap97d2 PE=3 SV=1 CANONICAL=E9QFI8-1" }, "locus": {} }, { "isoform_ac": "E9QFI8-1", "url": "https://www.uniprot.org/uniprotkb/E9QFI8/entry#E9QFI8-1", "sequence": { "sequence": "MQHQAYQPVVPCVNKYLQYRWDKNCYEIHRDKVKSAKPTINTSPPKTYSHLLVKLKKSQLEEERVSKIKRENEMLLHKMSHIMQTKGGVDCKNIYVKKSLGSEKKTTGTAPHHQRESAHPPAFVDLQAALQRSGVAGAVAQAPGAHGGHRQISAFLQRTGVLLATSVNRL", "length": 170, "header": "tr|E9QFI8-1|E9QFI8_DANRE Isoform 1 of Uncharacterized protein CFAP97D2 isoform X1 OS=Danio rerio OX=7955 GN=cfap97d2 PE=3 SV=1 CANONICAL=E9QFI8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561174", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561174", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1B0GU71-1", "protein_name": "Uncharacterized protein CFAP97D2", "gene_name": "CFAP97D2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHGAPRLTFPCASEYLWHAREKAYQDHRRKVQSAQPLVDTRAPLTFRHLHLKLKRLKLEEERLSVIERDNRLLLEKVASVMRTRGQTDSKNNSKHRRK", "length": 98 }, "evidence": [ { "id": "HGNC:53789", "url": "https://alliancegenome.org/gene/HGNC:53789#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-603", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-603#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "A0A8I6A9L5-1", "protein_name": "CFAP97 domain containing 2", "gene_name": "Cfap97d2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHRVPQLTTPWASRDLQRAWEKTYQNHRKKVQNAQPLVDTRPPQTYSHLHLKFKKLKMEEERLSIIDRNNYLLLQRVASAMKTGRRIDGQNNFTWRSLNRKSREQALMKVQKQNQAVPERLRSSEPWYGAQRWREDWTAMATRPCTCRHTWRKGADREAQQGHSLIWMRSLKRKG", "length": 175 }, "evidence": [ { "id": "HGNC:53789", "url": "https://alliancegenome.org/gene/HGNC:53789#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { 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], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 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"XP_005167840", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167840" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005167840", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167840" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FC91", "url": "https://www.uniprot.org/uniprotkb/E7FC91" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ankrd44", "url": "https://www.uniprot.org/uniprotkb/E7FC91", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-605", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-605", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000026028", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000026028", "database": "Bgee", "categories": [ "Gene 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"http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166:SF48", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24166:SF52", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24166:SF52", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24198:SF192", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24198:SF192", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005167840", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167840", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BF82", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BF82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BF82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BF82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BFV0", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BFV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BFV0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BFV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGU6", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGU6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGU6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGU6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGV3", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGV3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGV5", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGV5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGV5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGV5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGV6", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGV6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGW1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGW1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGW1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGW1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FC91", "url": "https://www.uniprot.org/uniprotkb/E7FC91", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FC91-1", "url": "https://www.uniprot.org/uniprotkb/E7FC91-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-605", "url": "https://zfin.org/ZDB-GENE-070912-605", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAVLKLVDQPPLVQAIFNGDPDEIRVLLCKSEDVNALDAEKRAPLHAAAFLGDAEITELLIVSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLAKGANINAFDKKDCRALHWAAYMGHLDVVCLLVSQGAEISCKDKRGYTPLHAAASNGQIAVVKHLLSLAVEIDEANAFGNTALHVACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNSGADVNVQSRDGKSPLHLTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADCTRRGVHGMFPLHLAALNAHADCCRKLLSSGRRYSIMCPLSNDSVLSAGFQIDTPDDLGRTCLHAAAAGGNVECVKLLLSSGADHNRRDKHGRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRTAVHYAAASDLDRRRRVVLEPESDGVQAEREKEAALCLEFLLQHGAGPSLKDKQGYSAVHYAAAYGHRHCLKLLLDRDENHQDDMENNQTRSPLHLAAYHGHAQALEVLLEGHCEVDQGDEVDRTPLALAALRGHTDCALTLLNHGASPRSRDTVRGRTPIHLAVMNGHTSCVRLLLEDSDNADLVDTADSQGQTPLMLAVMGGHVDAVSLLLERDASVDMADHHGLTGLHLGLLCGQEECVQSLLELEASVLLGDSRGRTAIHLAAARGHASWLSELLSIACIEPPLPPLRDNQGYTPLHYACYYGHEGCVEVILDQKDFCQFEGNPFTPLHCAVVNDHETCATLLLEAMGSKIVTCKDSKGRTPFHAAAFAGHVDCVQLLLSHNASVNEVDQSGRSALCMAAEKGRVEVVEALLAAADVNINLIDQKGNTALHLACSNGMEECALLLLGKLPDSALVATNSALQTPLHLAARSGMKQTVQELLSRGASVQVLDENGLTPALACAPSREVADCLALILATMMPFCSPCSSGAPSPGTLLKSLPHQAKSPQGPRSPKDPSGPSSEGTTTENDSDSETF", "length": 1068, "header": "tr|E7FC91-1|E7FC91_DANRE Isoform 1 of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1 OS=Danio rerio OX=7955 GN=ankrd44 PE=1 SV=2 CANONICAL=E7FC91-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BF82-1", "url": "https://www.uniprot.org/uniprotkb/E7FC91/entry#A0A8M2BF82-1", "sequence": { "sequence": "MAVLKLVDQPPLVQAIFNGDPDEIRVLLCKSEDVNALDAEKRAPLHAAAFLGDAEITELLIVSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLAKGANINAFDKKDCRALHWAAYMGHLDVVCLLVSQGAEISCKDKRGYTPLHAAASNGQIAVVKHLLSLAVEIDEANAFGNTALHVACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNSGADVNVQSRDGKSPLHLTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADCTRRGVHGMFPLHLAALNAHADCCRKLLSSGFQIDTPDDLGRTCLHAAAAGGNVECVKLLLSSGADHNRRDKHGRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRTAVHYAAASDLDRRRRVVLEPESDGVQAEREKEAALCLEFLLQHGAGPSLKDKQGYSAVHYAAAYGHRHCLKLLLDRDENHQDDMENNQTRSPLHLAAYHGHAQALEVLLEGHCEVDQGDEVDRTPLALAALRGHTDCALTLLNHGASPRSRDTVRGRTPIHLAVMNGHTSCVRLLLEDSDNADLVDTADSQGQTPLMLAVMGGHVDAVSLLLERDASVDMADHHGLTGLHLGLLCGQEECVQSLLELEASVLLGDSRGRTAIHLAAARGHASWLSELLSIACIEPPLPPLRDNQGYTPLHYACYYGHEGCVEVILDQKDFCQFEGNPFTPLHCAVVNDHETCATLLLEAMGSKIVTCKDSKGRTPFHAAAFAGHVDCVQLLLSHNASVNEVDQSGRSALCMAAEKGRVEVVEALLAAADVNINLIDQKGNTALHLACSNGMEECALLLLGKLPDSALVATNSALQTPLHLAARSGMKQTVQELLSRGASVQVLDENGLTPALACAPSREVADCLALILATMMPFCSPCSSGAPSPGTLLKSLPHQAKSPQGPRSPKDPSGPSSEGTTTENDSDSETF", "length": 1050, "header": "tr|A0A8M2BF82-1|E7FC91_DANRE Computationally mapped isoform of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1 OS=Danio rerio OX=7955 GN=ankrd44 PE=1 SV=1 CANONICAL=E7FC91-1" }, "locus": {} }, { "isoform_ac": "A0A8M2BFV0-1", "url": "https://www.uniprot.org/uniprotkb/E7FC91/entry#A0A8M2BFV0-1", "sequence": { "sequence": "MAVLKLVDQPPLVQAIFNGDPDEIRVLLCKSEDVNALDAEKRAPLHAAAFLGDAEITELLIVSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLAKGANINAFDKKDCRALHWAAYMGHLDVVCLLVSQGAEISCKDKRGYTPLHAAASNGQIAVVKHLLSLAVEIDEANAFGNTALHVACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNSGADVNVQSRDGKSPLHLTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADCTRRGVHGMFPLHLAALNAHADCCRKLLSSGRRYSIMCPLSNDSVLSAGFQIDTPDDLGRTCLHAAAAGGNVECVKLLLSSGADHNRRDKHGRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRTAVHYAAASDLDRRRRVVLEPESDGVQAEREKEAALCLEFLLQHGAGPSLKDKQGYSAVHYAAAYGHRHCLKLLLDRDENHQDDMENNQTRSPLHLAAYHGHAQALEVLLEGHCEVDQGDEVDRTPLALAALRGHTDCALTLLNHGASPRSRDTVRGRTPIHLAVMNGHTSCVRLLLEDSDNADLVDTADSQGQTPLMLAVMGGHVDAVSLLLERDASVDMADHHGLTGLHLGLLCGQEECVQSLLELEASVLLGDSRGRTAIHLAAARGHASWLSELLSIACIEPPLPPLRDNQGYTPLHYACYYGHEGCVEVILDQKDFCQFEGNPFTPLHCAVVNDHETCATLLLEAMGSKIVTCKDSKGRTPFHAAAFAGHVDCVQLLLSHNASVNEVDQSGRSALCMAAEKGRVEVVEALLAAADVNINLIDQKGNTALHLACSNGMEECALLLLGKLPDSALVATNSALQTPLHLAARSGMKQTVQELLSRGASVQVLDENAPELPPQAPC", "length": 997, "header": "tr|A0A8M2BFV0-1|E7FC91_DANRE Computationally mapped isoform of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1 OS=Danio rerio OX=7955 GN=ankrd44 PE=1 SV=1 CANONICAL=E7FC91-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGU6-1", "url": "https://www.uniprot.org/uniprotkb/E7FC91/entry#A0AC58GGU6-1", "sequence": { "sequence": "MAVLKLVDQPPLVQAIFNGDPDEIRVLLCKSEDVNALDAEKRAPLHAAAFLGDAEITELLIVSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLAKGANINAFDKKDCRALHWAAYMGHLDVVCLLVSQGAEISCKDKRGYTPLHAAASNGQIAVVKHLLSLAVEIDEANAFGNTALHVACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNSGADVNVQSRDGKSPLHLTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADCTRRGVHGMFPLHLAALNAHADCCRKLLSSGFQIDTPDDLGRTCLHAAAAGGNVECVKLLLSSGADHNRRDKHGRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRTAVHYAAASDLDRRCLEFLLQHGAGPSLKDKQGYSAVHYAAAYGHRHCLKLLLDRDENHQDDMENNQTRSPLHLAAYHGHAQALEVLLEGHCEVDQGDEVDRTPLALAALRGHTDCALTLLNHGASPRSRDTVRGRTPIHLAVMNGHTSCVRLLLEDSDNADLVDTADSQGQTPLMLAVMGGHVDAVSLLLERDASVDMADHHGLTGLHLGLLCGQEECVQSLLELEASVLLGDSRGRTAIHLAAARGHASWLSELLSIACIEPPLPPLRDNQGYTPLHYACYYGHEGCVEVILDQKDFCQFEGNPFTPLHCAVVNDHETCATLLLEAMGSKIVTCKDSKGRTPFHAAAFAGHVDCVQLLLSHNASVNEVDQSGRSALCMAAEKGRVEVVEALLAAADVNINLIDQKGNTALHLACSNGMEECALLLLGKLPDSALVATNSALQTPLHLAARSGMKQTVQELLSRGASVQVLDENGLTPALACAPSREVADCLALILATMMPFCSPCSSGAPSPGTLLKSLPHQAKSPQGPRSPKDPSGPSSEGTTTENDSDSETF", "length": 1028, "header": "tr|A0AC58GGU6-1|A0AC58GGU6_DANRE Computationally mapped isoform of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X4 OS=Danio rerio OX=7955 GN=ankrd44 PE=1 SV=1 CANONICAL=E7FC91-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGV3-1", "url": "https://www.uniprot.org/uniprotkb/E7FC91/entry#A0AC58GGV3-1", "sequence": { "sequence": "MAVLKLVDQPPLVQAIFNGDPDEIRVLLCKSEDVNALDAEKRAPLHAAAFLGDAEITELLIVSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLAKGANINAFDKKDCRALHWAAYMGHLDVVCLLVSQGAEISCKDKRGYTPLHAAASNGQIAVVKHLLSLAVEIDEANAFGNTALHVACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNSGADVNVQSRDGKSPLHLTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADCTRRGVHGMFPLHLAALNAHADCCRKLLSSGFQIDTPDDLGRTCLHAAAAGGNVECVKLLLSSGADHNRRDKHGRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRTAVHYAAASDLDRRCLEFLLQHGAGPSLKDKQGYSAVHYAAAYGHRHCLKLLLDRDENHQDDMENNQTRSPLHLAAYHGHAQALEVLLEGHCEVDQGDEVDRTPLALAALRGHTDCALTLLNHGASPRSRDTVRGRTPIHLAVMNGHTSCVRLLLEDSDNADLVDTADSQGQTPLMLAVMGGHVDAVSLLLERDASVDMADHHGLTGLHLGLLCGQEECVQSLLELEASVLLGDSRGRTAIHLAAARGHASWLSELLSIACIEPPLPPLRDNQGYTPLHYACYYGHEGCVEVILDQKDFCQFEGNPFTPLHCAVVNDHETCATLLLEAMGSKIVTCKDSKGRTPFHAAAFAGHVDCVQLLLSHNASVNEVDQSGRSALCMAAEKGRVEVVEALLAAADVNINLIDQKGNTALHLACSNGMEECALLLLGKLPDSALVATNSALQTPLHLAARSGMKQTVQELLSRGASVQVLDENAPELPPQAPC", "length": 957, "header": "tr|A0AC58GGV3-1|A0AC58GGV3_DANRE Computationally mapped isoform of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X7 OS=Danio rerio OX=7955 GN=ankrd44 PE=1 SV=1 CANONICAL=E7FC91-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGV5-1", "url": "https://www.uniprot.org/uniprotkb/E7FC91/entry#A0AC58GGV5-1", "sequence": { "sequence": "MPKHWMLMSVCLEFLLQHGAGPSLKDKQGYSAVHYAAAYGHRHCLKLLLDRDENHQDDMENNQTRSPLHLAAYHGHAQALEVLLEGHCEVDQGDEVDRTPLALAALRGHTDCALTLLNHGASPRSRDTVRGRTPIHLAVMNGHTSCVRLLLEDSDNADLVDTADSQGQTPLMLAVMGGHVDAVSLLLERDASVDMADHHGLTGLHLGLLCGQEECVQSLLELEASVLLGDSRGRTAIHLAAARGHASWLSELLSIACIEPPLPPLRDNQGYTPLHYACYYGHEGCVEVILDQKDFCQFEGNPFTPLHCAVVNDHETCATLLLEAMGSKIVTCKDSKGRTPFHAAAFAGHVDCVQLLLSHNASVNEVDQSGRSALCMAAEKGRVEVVEALLAAADVNINLIDQKGNTALHLACSNGMEECALLLLGKLPDSALVATNSALQTPLHLAARSGMKQTVQELLSRGASVQVLDENGLTPALACAPSREVADCLALILATMMPFCSPCSSGAPSPGTLLKSLPHQAKSPQGPRSPKDPSGPSSEGTTTENDSDSETF", "length": 552, "header": "tr|A0AC58GGV5-1|A0AC58GGV5_DANRE Computationally mapped isoform of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X8 OS=Danio rerio OX=7955 GN=ankrd44 PE=1 SV=1 CANONICAL=E7FC91-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGV6-1", "url": "https://www.uniprot.org/uniprotkb/E7FC91/entry#A0AC58GGV6-1", "sequence": { "sequence": "MAVLKLVDQPPLVQAIFNGDPDEIRVLLCKSEDVNALDAEKRAPLHAAAFLGDAEITELLIVSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLAKGANINAFDKKDCRALHWAAYMGHLDVVCLLVSQGAEISCKDKRGYTPLHAAASNGQIAVVKHLLSLAVEIDEANAFGNTALHVACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNSGADVNVQSRDGKSPLHLTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADCTRRGVHGMFPLHLAALNAHADCCRKLLSSGFQIDTPDDLGRTCLHAAAAGGNVECVKLLLSSGADHNRRDKHGRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRTAVHYAAASDLDRRRRVVLEPESDGVQAEREKEAALCLEFLLQHGAGPSLKDKQGYSAVHYAAAYGHRHCLKLLLDRDENHQDDMENNQTRSPLHLAAYHGHAQALEVLLEGHCEVDQGDEVDRTPLALAALRGHTDCALTLLNHGASPRSRDTVRGRTPIHLAVMNGHTSCVRLLLEDSDNADLVDTADSQGQTPLMLAVMGGHVDAVSLLLERDASVDMADHHGLTGLHLGLLCGQEECVQSLLELEASVLLGDSRGRTAIHLAAARGHASWLSELLSIACIEPPLPPLRDNQGYTPLHYACYYGHEGCVEVILDQKDFCQFEGNPFTPLHCAVVNDHETCATLLLEAMGSKIVTCKDSKGRTPFHAAAFAGHVDCVQLLLSHNASVNEVDQSGRSALCMAAEKGRVEVVEALLAAADVNINLIDQKGNTALHLACSNGMEECALLLLGKLPDSALVATNSALQTPLHLAARSGMKQTVQELLSRGASVQVLDENAPELPPQAPC", "length": 979, "header": "tr|A0AC58GGV6-1|A0AC58GGV6_DANRE Computationally mapped isoform of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X6 OS=Danio rerio OX=7955 GN=ankrd44 PE=1 SV=1 CANONICAL=E7FC91-1" }, "locus": {} }, { "isoform_ac": "A0AC58GGW1-1", "url": "https://www.uniprot.org/uniprotkb/E7FC91/entry#A0AC58GGW1-1", "sequence": { "sequence": "MAVLKLVDQPPLVQAIFNGDPDEIRVLLCKSEDVNALDAEKRAPLHAAAFLGDAEITELLIVSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLAKGANINAFDKKDCRALHWAAYMGHLDVVCLLVSQGAEISCKDKRGYTPLHAAASNGQIAVVKHLLSLAVEIDEANAFGNTALHVACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNSGADVNVQSRDGKSPLHLTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADCTRRGVHGMFPLHLAALNAHADCCRKLLSSGRRYSIMCPLSNDSVLSAGFQIDTPDDLGRTCLHAAAAGGNVECVKLLLSSGADHNRRDKHGRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRTAVHYAAASDLDRRCLEFLLQHGAGPSLKDKQGYSAVHYAAAYGHRHCLKLLLDRDENHQDDMENNQTRSPLHLAAYHGHAQALEVLLEGHCEVDQGDEVDRTPLALAALRGHTDCALTLLNHGASPRSRDTVRGRTPIHLAVMNGHTSCVRLLLEDSDNADLVDTADSQGQTPLMLAVMGGHVDAVSLLLERDASVDMADHHGLTGLHLGLLCGQEECVQSLLELEASVLLGDSRGRTAIHLAAARGHASWLSELLSIACIEPPLPPLRDNQGYTPLHYACYYGHEGCVEVILDQKDFCQFEGNPFTPLHCAVVNDHETCATLLLEAMGSKIVTCKDSKGRTPFHAAAFAGHVDCVQLLLSHNASVNEVDQSGRSALCMAAEKGRVEVVEALLAAADVNINLIDQKGNTALHLACSNGMEECALLLLGKLPDSALVATNSALQTPLHLAARSGMKQTVQELLSRGASVQVLDENGLTPALACAPSREVADCLALILATMMPFCSPCSSGAPSPGTLLKSLPHQAKSPQGPRSPKDPSGPSSEGTTTENDSDSETF", "length": 1046, "header": "tr|A0AC58GGW1-1|A0AC58GGW1_DANRE Computationally mapped isoform of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X3 OS=Danio rerio OX=7955 GN=ankrd44 PE=1 SV=1 CANONICAL=E7FC91-1" }, "locus": {} }, { "isoform_ac": "E7FC91-1", "url": "https://www.uniprot.org/uniprotkb/E7FC91/entry#E7FC91-1", "sequence": { "sequence": "MAVLKLVDQPPLVQAIFNGDPDEIRVLLCKSEDVNALDAEKRAPLHAAAFLGDAEITELLIVSGARVNAKDNMWLTPLHRAVASRSEEAVRVLIRHSADVNARDKNWQTPLHVAAANKALRCAEVIIPLLSSVNVSDRGGRTALHHAALNGHTEMVSLLLAKGANINAFDKKDCRALHWAAYMGHLDVVCLLVSQGAEISCKDKRGYTPLHAAASNGQIAVVKHLLSLAVEIDEANAFGNTALHVACFNGQDAVVSELIDYGANVSQPNNKGFTPLHFAAASTHGALCLEFLVNSGADVNVQSRDGKSPLHLTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADCTRRGVHGMFPLHLAALNAHADCCRKLLSSGRRYSIMCPLSNDSVLSAGFQIDTPDDLGRTCLHAAAAGGNVECVKLLLSSGADHNRRDKHGRTPLHYAAASRHFQCLETLVSCGTCINATDQWGRTAVHYAAASDLDRRRRVVLEPESDGVQAEREKEAALCLEFLLQHGAGPSLKDKQGYSAVHYAAAYGHRHCLKLLLDRDENHQDDMENNQTRSPLHLAAYHGHAQALEVLLEGHCEVDQGDEVDRTPLALAALRGHTDCALTLLNHGASPRSRDTVRGRTPIHLAVMNGHTSCVRLLLEDSDNADLVDTADSQGQTPLMLAVMGGHVDAVSLLLERDASVDMADHHGLTGLHLGLLCGQEECVQSLLELEASVLLGDSRGRTAIHLAAARGHASWLSELLSIACIEPPLPPLRDNQGYTPLHYACYYGHEGCVEVILDQKDFCQFEGNPFTPLHCAVVNDHETCATLLLEAMGSKIVTCKDSKGRTPFHAAAFAGHVDCVQLLLSHNASVNEVDQSGRSALCMAAEKGRVEVVEALLAAADVNINLIDQKGNTALHLACSNGMEECALLLLGKLPDSALVATNSALQTPLHLAARSGMKQTVQELLSRGASVQVLDENGLTPALACAPSREVADCLALILATMMPFCSPCSSGAPSPGTLLKSLPHQAKSPQGPRSPKDPSGPSSEGTTTENDSDSETF", "length": 1068, "header": "tr|E7FC91-1|E7FC91_DANRE Isoform 1 of Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B isoform X1 OS=Danio rerio OX=7955 GN=ankrd44 PE=1 SV=2 CANONICAL=E7FC91-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561373", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561373", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AGL0-1", "protein_name": "Ankyrin repeat domain 44", "gene_name": "Ankrd44", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVLKLCDQPPLVQAIFSGDPEEIRLLIHKTEDVNALDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQSPVHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHMEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNSGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGQKYSIVSLFSNEHVLSAGFEIDTPDTFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIKALVTTGANINETDNWGRTALHYAAASDMDRNKMILGNAHDNSEELERAREVKGKDAALCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNTGFEESDGGALKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALYLAAFKGHTECVEALVNQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNPEVVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDAVDTVGCTALHRGIMTGHEECVQMLLEQEASILCKDSRGRTPLHYAAARGHATWLNELVQIALSEEDCCLKDNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIGNPFTPLHCAIINGHESCASLLLGAIDSSIVSCRDDKGRTTLHAAAFGDHAECLQLLLRHDAQVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLAISKGHEKCALLILDKIQDESLINAKNSALQTPLHIAARNGLKVVVEELLAKGACVLAVDENASRSNGPRSPPGTAVRKEE", "length": 1011 }, "evidence": [ { "id": "E7FC91", "url": "https://omabrowser.org/oma/group/E7FC91/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B2RXR6-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B", "gene_name": "Ankrd44", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVLKLCEQPPLVQAIFSGDPEEIRMLIHKTEDVNALDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHMEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQISVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNSGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARHGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDTFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIKALVTTGANVNETDDWGRTALHYAAASDMDRNKMILGNAHDNSEELERAREVKEKDAALCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNTGFEESDGGALKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALYLAAFKGHTECVEALVNQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLETADNPEVVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDAVDIVGCTALHRGIMTGHEECVQMLLEQEASILCKDSRGRTPLHYAAARGHATWLNELLQIALSEEDCCLKDNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIGNPFTPLHCAIINGHESCASLLLGAIDPSIVSCRDDKGRTTLHAAAFGDHAECLQLLLRHDAQVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLAISKGHEKCALLILDKIQDESLINAKNSALQTPLHIAARNGLKVVVEELLAKGACVLAVDENASRSNGPRSPPGTAVRKEE", "length": 993 }, "evidence": [ { "id": "E7FC91", "url": "https://omabrowser.org/oma/group/E7FC91/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N8A2-1", "protein_name": "Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit B", "gene_name": "ANKRD44", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAVLKLTDQPPLVQAIFSGDPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKLLSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLVTTGANVNETDDWGRTALHYAAASDMDRNKTILGNAHDNSEELERARELKEKEATLCLEFLLQNDANPSIRDKEGYNSIHYAAAYGHRQCLELLLERTNSGFEESDSGATKSPLHLAAYNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHIDAVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNENCIEVLLEQKCFRKFIGNPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLHAAAFADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVNSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQDESLINEKNNALQTPLHVAARNGLKVVVEELLAKGACVLAVDENASRSNGPRSTPGTAVQKEE", "length": 993 }, "evidence": [ { "id": "E7FC91", "url": "https://omabrowser.org/oma/group/E7FC91/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1061, "end_pos": 1063, "annotation": "n_glycosylation_sequon" }, { "start_pos": 134, "end_pos": 136, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 483, "end_pos": 485, "annotation": "n_glycosylation_sequon" }, { "start_pos": 578, "end_pos": 580, "annotation": "n_glycosylation_sequon" }, { "start_pos": 876, "end_pos": 878, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1061, "end_pos": 1063 }, { "start_pos": 134, "end_pos": 136 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 483, "end_pos": 485 }, { "start_pos": 578, "end_pos": 580 }, { "start_pos": 876, "end_pos": 878 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F2P7-1", "uniprot_ac": "E7F2P7", "uniprot_id": "E7F2P7_DANRE", "mass": { "chemical_mass": 126010.0, "monoisotopic_mass": 126010.0 }, "refseq": { "ac": "NP_001420015", "name": "F-box only protein 38", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420015" }, "gene_names": [ { "name": "fbxo38", "type": "recommended", "evidence": [ { "id": "E7F2P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2P7" } ] }, { "name": "fbxo38", "type": "synonym", "evidence": [ { "id": "NP_001420015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420015" } ] }, { "name": "fc18a08", "type": "synonym", "evidence": [ { "id": "NP_001420015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420015" }, { "id": "E7F2P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2P7" } ] }, { "name": "wu:fc18a08", "type": "synonym", "evidence": [ { "id": "NP_001420015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420015" }, { "id": "E7F2P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2P7" } ] } ], "protein_names": [ { "name": "F-box only protein 38", "type": "synonym", "evidence": [ { "id": "NP_001420015", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420015" }, { "id": "E7F2P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2P7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01020465.1, GFIL01010399.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476736, SAMEA4476739 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000014.1. On Jun 25, 2025 this sequence version replaced NP_001420015.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001420015", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420015" } ] } ], "disease": [ { "disease_id": "DOID:0111210", "recommended_name": { "id": "DOID:0111210", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111210", "name": "autosomal dominant distal hereditary motor neuronopathy 6", "description": "A distal hereditary motor neuropathy that has_material_basis_in heterozygous mutation in the FBXO38 gene on 5q32." }, "synonyms": [ { "id": "DOID:0111210", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111210", "name": "HMN IID", "description": "" }, { "id": "DOID:0111210", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111210", "name": "HMN2D", "description": "" }, { "id": "DOID:0111210", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111210", "name": "distal hereditary motor neuropathy type IID", "description": "" }, { "id": "DOID:0111210", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111210", "name": "distal spinal muscular atrophy with calf predominance", "description": "" }, { "id": "DOID:0111210", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111210", "name": "distal hereditary motor neuronopathy type 2D", "description": "" }, { "id": "MONDO:0014259", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014259", "name": "neuronopathy, distal hereditary motor, type 2D", "description": "Any neuronopathy, distal hereditary motor in which the cause of the disease is a mutation in the FBXO38 gene." }, { "id": "MONDO:0014259", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014259", "name": "FBXO38 neuronopathy, distal hereditary motor", "description": "" }, { "id": "MONDO:0014259", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014259", "name": "neuronopathy, distal hereditary motor caused by mutation in FBXO38", "description": "" }, { "id": "MONDO:0014259", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014259", "name": "HMN2D", "description": "" }, { "id": "MONDO:0014259", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014259", "name": "neuronopathy, distal hereditary motor, type IID", "description": "" }, { "id": "MIM:615575", "resource": "MIM", "url": "https://www.omim.org/entry/615575", "name": "Neuronopathy, distal hereditary motor, autosomal dominant 6", "description": "Neuronopathy, distal hereditary motor, autosomal dominant 6" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111210", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111210" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F2P7", "url": "https://www.uniprot.org/uniprotkb/E7F2P7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fbxo38", "url": "https://www.uniprot.org/uniprotkb/E7F2P7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-2797", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2797", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd22107", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22107", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "799091", "url": "https://www.ncbi.nlm.nih.gov/gene/799091", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042354", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042354", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:799091", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799091", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M2BH07", "url": "https://www.orthodb.org/?gene=A0A8M2BH07", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F2P7", "url": "https://www.orthodb.org/?gene=E7F2P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14753", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14753", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14753:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14753:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001420015", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001420015", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BH07", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BH07", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BH07-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BH07-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F2P7", "url": "https://www.uniprot.org/uniprotkb/E7F2P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F2P7-1", "url": "https://www.uniprot.org/uniprotkb/E7F2P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-2797", "url": "https://zfin.org/ZDB-GENE-030131-2797", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMSPRRKVTRTHSLGGGTLSSLGHEEPKDYINELSHEVLCHIFRYLPMQDIMCMECLSRKLREAVTLYLRVVKVVDLCASRWWEYMPSGFTDSSFLMLMKKMPDLEQLYGLHPRYLERRRVRGYEAFSIPGVLEALQACPNLIGVETSHLELVEAVWNYMPQVHILGKFRNRNGAFPIPSENKLTIPAAAKIQTLHLVGVNVPEIPCLSMLRHLYLKWVRLTKPQPFKDFLCVNLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEQLELVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVFGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQCNMSHAELVKYGLADVIENPGIITDIGMKAVNEVFTSIKYLVIYNCPHLHNPHNWITDHSRWSRLVDLTLVRCHAIKLESFSQFIELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDNDNNNNNNHQNNNDANIPPNNNDNQVENVPQQNHRGPEAEIPVVEGMVAENIEPEPVLVAANPQEENQSSSQTPNPSLEQDEEQAGPSGVQTSVKKPSVVVSDSDSEDEYSPVRTPAAARSQGQYPETEAQGKSSTAGTPHGKGKTPLRRRGPQPQELSCEKGCQVTSEQIKADMKAATETAERGAKDRNSGSAPASNYSAGSCVCSIRWREDSANQDDQGGAGDMVRTRCTCNRSRSSSENRTRSGHGLPTGGDNHRAEEMEDRHSNASARTPSSFEGHNNRTAGHSSHRGPTDEFPRRPITRARSRLSSVPLVCESELPKAKPRTAVKRKRMADKSTSTSDPVTEDDHVQVLSLKSKNLVGITLTNCGITDLVLKECPKMMFVHATRCRVLKHLVVESAPIVNRFDYAQCKKLDMEQVLDQILRMPPERNRIIYMRPMQQIDSLALEKKLFSGPYPYHIAIIHEFSNPPNVRNKVRVRSWMDTIANISQELIKYEFFPEATRTEEDVKKYPSYPWGRDIYTLEGVVDGAPYSMITDFPWLRSLRTAEPNTYARYDFEDDESTTIYAPRRKGQLSADICMETIGEEISERRQTCKGVFQRVVVVFIHYCDVRGEPVEDDYI", "length": 1120, "header": "tr|E7F2P7-1|E7F2P7_DANRE Isoform 1 of F-box only protein 38 OS=Danio rerio OX=7955 GN=fbxo38 PE=4 SV=1 CANONICAL=E7F2P7-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BH07-1", "url": "https://www.uniprot.org/uniprotkb/E7F2P7/entry#A0A8M2BH07-1", "sequence": { "sequence": "MMSPRRKVTRTHSLGGGTLSSLGHEEPKDYINELSHEVLCHIFRYLPMQDIMCMECLSRKLREAVTLYLRVVKVVDLCASRWWEYMPSGFTDSSFLMLMKKMPDLEQLYGLHPRYLERRRVRGYEAFSIPGVLEALQACPNLIGVETSHLELVEAVWNYMPQVHILGKFRNRNGAFPIPSENKLTIPAAAKIQTLHLVGVNVPEIPCLSMLRHLYLKWVRLTKPQPFKDFLCVNLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEQLELVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVFGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQCNMSHAELVKYGLADVIENPGIITDIGMKAVNEVFTSIKYLVIYNCPHLHNPHNWITDHSRWSRLVDLTLVRCHAIKLESFSQFIELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDNDNNNNNNHQNNNDANIPPNNNDNQVENVPQQNHRGPEEIPVVEGMVAENMEPEPVLVAANPQEENQSSSQTPNPSLEQDEEQAGPSGVQTSVKKPSVVVSDSDSEDEYSPVRTPAAARSQGQYPETEAQGKSSTAGTPHGKGKTPLRRRGPQPQELSCEKGCQVTSEQIKADMKATTETAERGAKDRNSGSAPASNYSAGSCVCSIRWREDSANQDDQGGAGDMVRTRCTCNRSRSSSENRTRSGHGLPTGGDNHRAEEMEDRHSNASARTPSSFEGHNNRTAGHSSHRGPTDEFPRRPITRARSRLSSVPLVCESELPKAKPRTAVKRKRMADKSTSTSDPVTEDDHVQVLSLKSKNLVGITLTNCGITDLVLKECPKMMFVHATRCRVLKHLVVESAPIVNRFDYAQCKKLDMEQVLDQILRMPPERNRIIYMRPMQQIDSLALEKKLFSGPYPYHIAIIHEFSNPPNVRNKVRVRSWMDTIANISQELIKYEFFPEATRTEEDVKKYPSYPWGRDIYTLEGVVDGAPYSMITDFPWLRSLRTAEPNTYARYDFEDDESTTIYAPRRKGQLSADICMETIGEEISERRQTCKGVFQRVVVVFIHYCDVRGEPVEDDYI", "length": 1119, "header": "tr|A0A8M2BH07-1|E7F2P7_DANRE Computationally mapped isoform of F-box only protein 38 OS=Danio rerio OX=7955 GN=fbxo38 PE=4 SV=2 CANONICAL=E7F2P7-1" }, "locus": {} }, { "isoform_ac": "E7F2P7-1", "url": "https://www.uniprot.org/uniprotkb/E7F2P7/entry#E7F2P7-1", "sequence": { "sequence": "MMSPRRKVTRTHSLGGGTLSSLGHEEPKDYINELSHEVLCHIFRYLPMQDIMCMECLSRKLREAVTLYLRVVKVVDLCASRWWEYMPSGFTDSSFLMLMKKMPDLEQLYGLHPRYLERRRVRGYEAFSIPGVLEALQACPNLIGVETSHLELVEAVWNYMPQVHILGKFRNRNGAFPIPSENKLTIPAAAKIQTLHLVGVNVPEIPCLSMLRHLYLKWVRLTKPQPFKDFLCVNLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEQLELVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVFGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQCNMSHAELVKYGLADVIENPGIITDIGMKAVNEVFTSIKYLVIYNCPHLHNPHNWITDHSRWSRLVDLTLVRCHAIKLESFSQFIELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDNDNNNNNNHQNNNDANIPPNNNDNQVENVPQQNHRGPEAEIPVVEGMVAENIEPEPVLVAANPQEENQSSSQTPNPSLEQDEEQAGPSGVQTSVKKPSVVVSDSDSEDEYSPVRTPAAARSQGQYPETEAQGKSSTAGTPHGKGKTPLRRRGPQPQELSCEKGCQVTSEQIKADMKAATETAERGAKDRNSGSAPASNYSAGSCVCSIRWREDSANQDDQGGAGDMVRTRCTCNRSRSSSENRTRSGHGLPTGGDNHRAEEMEDRHSNASARTPSSFEGHNNRTAGHSSHRGPTDEFPRRPITRARSRLSSVPLVCESELPKAKPRTAVKRKRMADKSTSTSDPVTEDDHVQVLSLKSKNLVGITLTNCGITDLVLKECPKMMFVHATRCRVLKHLVVESAPIVNRFDYAQCKKLDMEQVLDQILRMPPERNRIIYMRPMQQIDSLALEKKLFSGPYPYHIAIIHEFSNPPNVRNKVRVRSWMDTIANISQELIKYEFFPEATRTEEDVKKYPSYPWGRDIYTLEGVVDGAPYSMITDFPWLRSLRTAEPNTYARYDFEDDESTTIYAPRRKGQLSADICMETIGEEISERRQTCKGVFQRVVVVFIHYCDVRGEPVEDDYI", "length": 1120, "header": "tr|E7F2P7-1|E7F2P7_DANRE Isoform 1 of F-box only protein 38 OS=Danio rerio OX=7955 GN=fbxo38 PE=4 SV=1 CANONICAL=E7F2P7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7F2P7", "url": "https://www.uniprot.org/uniprotkb/E7F2P7" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:799091", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799091", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y5Q8-1", "protein_name": "F-box protein 38", "gene_name": "FBXO38", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGPRRKNVKPCSVNREGSESTKADEPKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKLKEAVTLYLRVVKVVDLCAGRWWEYMPTGFTDSSFLTLLRKMPDIEQLYGLHPRYLERRRVRGHEAFSIPGVLEALQACPNLLGVETSHLELVEAIWTYMPQVHILGKFRNRNGAFPIPPENKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYLKWVRLTKPQPFKDFLCISLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEHLELVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVLGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQCKMTNGDLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLVIYNCPHLHNPNNWITDHSRWTRLVDLTLVRCHAIKLDSFSQFIELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDNDNNNNHQNNNNPNIHHNNHQHPNDQNEENELRQDGQAEGQQIAAEALNEMEEVAPEEGIAAGQGHNDVPAHSQAVVPMEVDEEQAGPSGIQPVVKAAPITVHDSDSEDEEENMGTRACITNSIAQNYSDGEEKTRDAVETKEPSVSGKGKTPLRKRCSASQVGQAKQFHMEESSCEKGCQVTSEQIKADMKAASDMPERNKGKDSYPSCGNATGSTGSSSSCSAISSSPDCAQTASSHCAGTSLTAADESRQCVCSPCKSEGSSERETEETSVCSRCSCYKPQDTQRRTSGCCDGECPSTSGACRNGRSSTGSDFALRTLPNCGSPREASGERTSGSACGPASGEESMSSQQRSCEMQYKEEYPRRPLTRARSKLSHVPLVSESEVTKPRPRQTTKRKRTADKSTSTSDPVIEDDHVQVLTLKSKNLVGITLTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPVVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKIFSGPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRTEEDLKKYTKYPWGRDIYTLEGIVDGAPYSMITDFPWLRSLRTAEPNSYARYDFEDDERTTIYAPRRKGQLSADICMETIGEEISELRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI", "length": 1186 }, "evidence": [ { "id": "E7F2P7", "url": "https://omabrowser.org/oma/group/E7F2P7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZIK8-1", "protein_name": "F-box protein 38", "gene_name": "Fbxo38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGPRKKSVKVCVMDSEVPEEMTADEEKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKLKEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDCSFLTLLKKMPDVEQLYGLHPRYLERRRVRGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPENKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVLGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFVELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDNDNNAQNNNANIHDNNHHHPDDSDDDNDFRQDLQQGEAQFAADALNEMEDMVQDDGEVVAESGSGVPAHQGVLPVDADEEQAGPSGLQRVVKPTPIAVHDSESDDEEDSLELQEVWIPKNGARRYSEREEKTGDSGQPRETAAVSGKGKTPLRKRYNNSHQMGQAKQFPLEESSCEKGCQVTSEQIKADMKAARDISEKKKTKDVYPSCSTTAASTVGNSSSPSTASQSPDFVRTVTSGGSSEPSPPEVDVSRQCVCSPGGSEDSEAMEEGDAESSVCPRCCCLRPQESQRRTSRRSDEERPSTSRACVVNGADGTRSAFSFRTLPQGGSSGPAHDERTNGSGCGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVPLIPESEIAKTKPCHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICVIHEFSNPPNVRNKVRIRNWMDTIANINQELIKYEFFLEATRTEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKRGVFQRVVAIFIHYCDVNGEPVEDDYI", "length": 1190 }, "evidence": [ { "id": "HGNC:28844", "url": "https://alliancegenome.org/gene/HGNC:28844#orthology", "database": "AGR" }, { "id": "MGI:2444639", "url": "https://alliancegenome.org/gene/MGI:2444639#orthology", "database": "AGR" }, { "id": "RGD:1311505", "url": "https://alliancegenome.org/gene/RGD:1311505#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2797", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2797#orthology", "database": "AGR" }, { "id": "E7F2P7", "url": "https://omabrowser.org/oma/group/E7F2P7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PIJ6-1", "protein_name": "F-box only protein 38", "gene_name": "FBXO38", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGPRKKSVKTCIMNNEIPEEMTADETKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKLKEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDASFLTLLKKMPDVEQLYGLHPRYLERRRVRGHEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPENKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVLGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWTRLVDINLVRCHALKLDSFGQFIELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDDNNAQNNNANIHDNNHHHPDDSDEENDFRQDLQPGEQQFAADALNEMEDIVQEDGEVVAESGNNTPAHSQAIIPVDVDEEQAGPSGLQRVVKPTSITVHDSESDDEEDSLELQEVWIPKNGTRRYSEREEKTGESVQSRELSVSGKGKTPLRKRYNSHQMGQSKQFPLEESSCEKGCQVTSEQIKADMKAARDIPEKKKNKDVYPSCSSTTASTVGNSSSHNTASQSPDFVRTVNSGGSSEPSPTEVDVSRQCACSPGGSEDSEAMEEGDAESSVCPRCCCHRPQESQRRTSRCSDEERPSTSRACVVNGPDGTRSAFSFRTLPQGGSSGPAHDERTNGSGSGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVLLVSESEVAKTKPRHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRSWMDTIANINQELIKYEFFPEATRSEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRAAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKKGVFQRVVAIFIHYCDVNGEPVEDDYI", "length": 1188 }, "evidence": [ { "id": "HGNC:28844", "url": "https://alliancegenome.org/gene/HGNC:28844#orthology", "database": "AGR" }, { "id": "MGI:2444639", "url": "https://alliancegenome.org/gene/MGI:2444639#orthology", "database": "AGR" }, { "id": "RGD:1311505", "url": "https://alliancegenome.org/gene/RGD:1311505#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2797", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2797#orthology", "database": "AGR" }, { "id": "E7F2P7", "url": "https://omabrowser.org/oma/group/E7F2P7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BMI0-1", "protein_name": "F-box only protein 38", "gene_name": "Fbxo38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGPRKKSAKVCVMDSEVAEEMTADEEKDYMNQLSHEVLCHIFRYLPLQDIMCMECLSRKLKEAVTLYLRVVRVVDLCAGRWWEYMPSGFTDSSFLTLLKKMPDVEQLYGLHPRYLERRRVRGQEAFSIPGVLEALQACPNLVGVETSHLELVESIWTYMPHVHILGKFRNRNGAFPIPPENKLKIPIGAKIQTLHLVGVNVPEIPCIPMLRHLYMKWVRLTKPQPFKDFLCISLRTFVMRNCAGPTNSLKYVPLVTGLASARNLEHLEMVRVPFLGGLIQHVVEDSWRSGGFRNLHTIVLGACKNALEVDLGYLIITAARRLHEVRIQPSLTKDGVFSALKMAELEFPQFETLHLGYVDEFLLQSRMANADLVKYGLADVVENPGIITDIGMKAVNEVFSCIKYLAIYNCPHLHNPYNWISDHSRWMRLVDINLVRCHALKLDSFGQFVELLPSLEFISLDQMFREPPKGCARVGLSAGTGIGVSSALVSNQNSNNDNDNNAPNNNANLHDNNHHHPDDSDDDNDFRPDLQAGEAQFAADALNEMEDMVQEDGELVAESGNGMPAHNREVLPVDADEEQAGPSGLQRVVKPTPIADHDSESDDEEDSLELQEVWAPKNGTRRYSEREEKTGDSGQSRETAVSGKGKTPLRKRCNNSHQTGQAKPFPLEESSCEKGCQVTSEQIKADMKAARDVSEKKKSKDVYPSCSSSSSSTAASTAGNASSPSTASQSPDFARTVTSSGSSEPSPPEVDVSRQCVCSPGGSEDSEAMEEGDAESSVCPRCCCLRPQESQRRTGRCSDEERPSTSRACVVNGADGTRSAFSFRTLPQGGSSGPAHDERTNGSGCGATGEDRRGSSQPESCDVQSNEDYPRRPLTRARSRLSHVPLISESEVAKTKPCHAMKRKRTADKSTSTSDPVIEDDHVQVLVLKSKNLVGVTMTNCGITDLVLKDCPKMMFIHATRCRVLKHLKVENAPIVNRFDYAQCKKLNMDQVLDQILRMPPERNRIIYLRPMQQVDTLTLEQKLFSGPYPYHICIIHEFSNPPNVRNKVRIRNWMDTIANINQELIKYEFFLEATRTEEDLKKYPKYPWGREIYTLEGVVDGAPYSMISDFPWLRSLRTAEPNSFARYDFEDDEESTIYAPRRKGQLSADICMETIGEEISEMRQMKRGIFQRVVAIFIHYCDVNGEPVEDDYI", "length": 1194 }, "evidence": [ { "id": "HGNC:28844", "url": "https://alliancegenome.org/gene/HGNC:28844#orthology", "database": "AGR" }, { "id": "MGI:2444639", "url": "https://alliancegenome.org/gene/MGI:2444639#orthology", "database": "AGR" }, { "id": "RGD:1311505", "url": "https://alliancegenome.org/gene/RGD:1311505#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-2797", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2797#orthology", "database": "AGR" }, { "id": "E7F2P7", "url": "https://omabrowser.org/oma/group/E7F2P7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "E7F2P7", "url": "https://www.uniprot.org/uniprotkb/E7F2P7" } ], "pmid": "" }, { "name": "positive regulation of T cell mediated immune response to tumor cell", "id": "GO:0002842", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002842", "evidence": [ { "database": "UniProtKB", "id": "E7F2P7", "url": "https://www.uniprot.org/uniprotkb/E7F2P7" } ], "pmid": "" }, { "name": "protein K48-linked ubiquitination", "id": "GO:0070936", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070936", "evidence": [ { "database": "UniProtKB", "id": "E7F2P7", "url": "https://www.uniprot.org/uniprotkb/E7F2P7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7F2P7", "url": "https://www.uniprot.org/uniprotkb/E7F2P7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7F2P7", "url": "https://www.uniprot.org/uniprotkb/E7F2P7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "E7F2P7", "url": "https://www.uniprot.org/uniprotkb/E7F2P7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 367, "end_pos": 369, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 696, "end_pos": 698, "annotation": "n_glycosylation_sequon" }, { "start_pos": 732, "end_pos": 734, "annotation": "n_glycosylation_sequon" }, { "start_pos": 740, "end_pos": 742, "annotation": "n_glycosylation_sequon" }, { "start_pos": 766, "end_pos": 768, "annotation": "n_glycosylation_sequon" }, { "start_pos": 780, "end_pos": 782, "annotation": "n_glycosylation_sequon" }, { "start_pos": 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"https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121214-302", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000090537", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000090537", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100001239", "url": "https://www.ncbi.nlm.nih.gov/gene/100001239", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011990", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011990", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100001239", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001239", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YERAKTC", "url": "https://omabrowser.org/oma/group/YERAKTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BHB7", "url": "https://www.orthodb.org/?gene=A0A8M2BHB7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FCM5", "url": "https://www.orthodb.org/?gene=E7FCM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10271", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10271", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10271:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10271:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13181", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13181", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001177393", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001177393", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BHB7", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BHB7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BHB7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BHB7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FCM5", "url": "https://www.uniprot.org/uniprotkb/E7FCM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FCM5-1", "url": "https://www.uniprot.org/uniprotkb/E7FCM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-121214-302", "url": "https://zfin.org/ZDB-GENE-121214-302", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSEQSYSQDSLQLKLDQLDCHFTWDIRKDDLDLTNVLNRLEEQVKMGLGREEGVARTHCSLGYAKCLLGNKEEALTHLSRSETLIKEKLGNNCDKTLIVTYGNFAWMNYQMENYTECESYLVKLQKIHEMFPAESVPEVLGEKGWAYLKFSYKYYDRAVEAFQKAVELDPENSEWNAGYATALYRIETALNPFRTEMDTPCIVDSPAIKQLRLAISINPDDDSLRALLGLRLFLCSKKLMKESEKLMETALNGSPEHPHVTRYVAKFFRNQGSVDRSIELLETALQKSPNSGFIHHQLAMCYKTKKIDLQKEKGDRHQINNARNQCIYYLEKATSLKDSFIIAMCELAMQYGEKHELSKAEGLFKKTFITAKEKNECIHIVHCYYAEFQQYSNRCELLAIEHYKKCLTMNPDSSEGNRSAYKLMNIAKKHLKANPNNWDAHEILGLIYQKKGEMFGDTKSYAGTGDEENDECLHNLLEINCKI", "length": 483, "header": "tr|E7FCM5-1|E7FCM5_DANRE Isoform 1 of Interferon-induced protein with tetratricopeptide repeats 11 OS=Danio rerio OX=7955 GN=ifit11 PE=3 SV=1 CANONICAL=E7FCM5-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BHB7-1", "url": "https://www.uniprot.org/uniprotkb/E7FCM5/entry#A0A8M2BHB7-1", "sequence": { "sequence": "MSEQSQDSLQLKLDQLDCHFTWDIRKDDLDLTNVLNRLEEQVKMGLGREEGVARTHCSLGYAKCLLGNKEEALTHLSRSETLIKEKLGNNCDKTLIVTYGNFAWMNYQMENYTECESYLVKLQKIHEMFPAESVPEVLGEKGWAYLKFSYKYYDRAVEAFQKAVELDPENSEWNAGYATALYRIETALNPFRTEMDTPCIVDSPAIKQLRLAISINPDDDSLRALLGLRLFLCSKKLMKESEKLMETALNGSPEHPHVTRYVAKFFRNQGSVDRSIELLETALQKSPNSGFIHHQLAMCYKTKKIDLQKEKGDRHQINNARNQCIYYLEKATSLKDSFIIAMCELAMQYGEKHELSKAEGLFKKTFITAKEKNECIHIVHCYYAEFQQYSNRCELLAIEHYKKCLTMNPDSSEGNRSAYKLMNIAKKHLKANPNNWDAHEILGLIYQKKGEMFGDTKSYAGTGDEENDECLHNLLEINCKI", "length": 481, "header": "tr|A0A8M2BHB7-1|E7FCM5_DANRE Computationally mapped isoform of Interferon-induced protein with tetratricopeptide repeats 11 OS=Danio rerio OX=7955 GN=ifit11 PE=3 SV=1 CANONICAL=E7FCM5-1" }, "locus": {} }, { "isoform_ac": "E7FCM5-1", "url": "https://www.uniprot.org/uniprotkb/E7FCM5/entry#E7FCM5-1", "sequence": { "sequence": "MSEQSYSQDSLQLKLDQLDCHFTWDIRKDDLDLTNVLNRLEEQVKMGLGREEGVARTHCSLGYAKCLLGNKEEALTHLSRSETLIKEKLGNNCDKTLIVTYGNFAWMNYQMENYTECESYLVKLQKIHEMFPAESVPEVLGEKGWAYLKFSYKYYDRAVEAFQKAVELDPENSEWNAGYATALYRIETALNPFRTEMDTPCIVDSPAIKQLRLAISINPDDDSLRALLGLRLFLCSKKLMKESEKLMETALNGSPEHPHVTRYVAKFFRNQGSVDRSIELLETALQKSPNSGFIHHQLAMCYKTKKIDLQKEKGDRHQINNARNQCIYYLEKATSLKDSFIIAMCELAMQYGEKHELSKAEGLFKKTFITAKEKNECIHIVHCYYAEFQQYSNRCELLAIEHYKKCLTMNPDSSEGNRSAYKLMNIAKKHLKANPNNWDAHEILGLIYQKKGEMFGDTKSYAGTGDEENDECLHNLLEINCKI", "length": 483, "header": "tr|E7FCM5-1|E7FCM5_DANRE Isoform 1 of Interferon-induced protein with tetratricopeptide repeats 11 OS=Danio rerio OX=7955 GN=ifit11 PE=3 SV=1 CANONICAL=E7FCM5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Lineage-specific expansion of IFIT gene family: an insight into coevolution with IFN gene family.", "journal": "PLoS ONE", "date": "2013", "authors": "Liu Ying, Zhang Yi-Bing, Liu Ting-Kai, Gui Jian-Fang", "evidence": [ { "database": "UniProtKB", "id": "E7FCM5", "url": "https://www.uniprot.org/uniprotkb/E7FCM5" } ], "reference": [ { "type": "PubMed", "id": "23818968", "url": "https://glygen.org/publication/PubMed/23818968" } ] }, { "title": "Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.", "journal": "J. Immunol.", "date": "2014", "authors": "Briolat Val\u00e9rie, Jouneau Luc, Carvalho Ralph, Palha Nuno, Langevin Christelle, Herbomel Philippe, Schwartz Olivier, Spaink Herman P, Levraud Jean-Pierre, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "E7FCM5", "url": "https://www.uniprot.org/uniprotkb/E7FCM5" } ], "reference": [ { "type": "PubMed", "id": "24683187", "url": "https://glygen.org/publication/PubMed/24683187" } ] }, { "title": "Interferon-induced genes of the expanded IFIT family show conserved antiviral activities in non-mammalian species.", "journal": "PLoS ONE", "date": "2014", "authors": "Varela M\u00f3nica, Diaz-Rosales Patricia, Pereiro Patricia, Forn-Cun\u00ed Gabriel, Costa Maria M, Dios Sonia, Romero Alejandro, Figueras Antonio, Novoa Beatriz", "evidence": [ { "database": "UniProtKB", "id": "E7FCM5", "url": "https://www.uniprot.org/uniprotkb/E7FCM5" } ], "reference": [ { "type": "PubMed", "id": "24950240", "url": "https://glygen.org/publication/PubMed/24950240" } ] }, { "title": "Interferon-independent antiviral activity of 25-hydroxycholesterol in a teleost fish.", "journal": "Antiviral Res.", "date": "2017", "authors": "Pereiro Patricia, Forn-Cun\u00ed Gabriel, Dios Sonia, Coll Julio, Figueras Antonio, Novoa Beatriz", "evidence": [ { "database": "UniProtKB", "id": "E7FCM5", "url": "https://www.uniprot.org/uniprotkb/E7FCM5" } ], "reference": [ { "type": "PubMed", "id": "28789986", "url": "https://glygen.org/publication/PubMed/28789986" } ] }, { "title": "In vivo Host-Pathogen Interaction as Revealed by Global Proteomic Profiling of Zebrafish Larvae.", "journal": "Front. Cell. Infect. Microbiol.", "date": "2017", "authors": "D\u00edaz-Pascual Francisco, Ort\u00edz-Sever\u00edn Javiera, Varas Macarena A, Allende Miguel L, Ch\u00e1vez Francisco P", "evidence": [ { "database": "UniProtKB", "id": "E7FCM5", "url": "https://www.uniprot.org/uniprotkb/E7FCM5" } ], "reference": [ { "type": "PubMed", "id": "28791256", "url": "https://glygen.org/publication/PubMed/28791256" } ] }, { "title": "Characterization of zebrafish (Danio rerio) muscle ankyrin repeat proteins reveals their conserved response to endurance exercise.", "journal": "PLoS ONE", "date": "2018", "authors": "Boskovic Srdjan, Mar\u00edn-Juez Rub\u00e9n, Jasnic Jovana, Reischauer Sven, El Sammak Hadil, Kojic Ana, Faulkner Georgine, Radojkovic Dragica, Stainier Didier Y R, Kojic Snezana", "evidence": [ { "database": "UniProtKB", "id": "E7FCM5", "url": "https://www.uniprot.org/uniprotkb/E7FCM5" } ], "reference": [ { "type": "PubMed", "id": "30252882", "url": "https://glygen.org/publication/PubMed/30252882" } ] } ], "pathway": [ { "id": "dre:100001239", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001239", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A9J7FKA5-1", "protein_name": "Interferon-induced protein with tetratricopeptide repeats 1 isoform X1", "gene_name": "LOC100772509", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRDFEGFPQETKLLRDHAGGDQVKENLLQLRCHFTWGLLIEDVDIPDLEMRIQEEVQFLDIKNPAGMHNLLAYVRHLKGQHEEALESVKEAEALTQKEKLDKRSLVTWGNCAWVHYNMDSLSEAQAYLDKVENTCKEFASPFRYRMECAEIDCEEGWALLKCGGQNYRRAMACFVKALEMEPENPEYNTGYAVAAYREDFDDHNFSLEPLRKAVSLNPEDPYLKVYLALKLQDVGETPEAETHIEEALSSTSCQNYVFRYAAKYYRRKGCIDKALHLLHRALQASPDSGYLHYQIGLCYSKQMIQLKTSRNQQPRSQGNLQELAEQAICEFQQTLKLRPTVEMAYVCMAEAQAELHQYEEAEANFQKALDMKSVKCHIEQDIHFRYGRFQQFHQKSEDKAITHYLKGLKIEESSFARRKLLKALEKVVERRVDHNIRPVESMGLLGLVHKLKGNMQEALLCYERALRLTGEMNPVF", "length": 476 }, "evidence": [ { "id": "E7FCM5", "url": "https://omabrowser.org/oma/group/E7FCM5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1LPS6-1", "protein_name": "Interferon-induced protein with tetratricopeptide repeats 1", "gene_name": "Ifit1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMNRMKHAQEPISYGSEFRVSIYTELRENADGDQVMENLLQLRCHFTWGLLFEKNDIPDLEVRISEQVQFLDIKNSLGMHNLQAYVRHLKGEQEEALQSLKEAEALIEGEQLGKRSLVTWGNCAWVHYHRGSLAEAQIYLDKVENVCREFSSPFHYRMECAEIDCEEGWALLKCGGSNYMRAMACFAKALQVDPENPEYNAGYAVVAYRQDFDDNHVSLEPLRKAVRLNPEDPHLKVLLALKLQDLGEQDEAETHIEEALSSTSCQSYVFRYAAKYFRRKGDINEALHLLHRALQTSPSSGYLHYQKGLCYKQQMIQLKTSGNRQARRQENIQELAHQAICEFQETLNLRPTFEMAYVCMAEMQAEIGQYEEAEGNFQEALNLNNLVAHIEQDIHFRYGRFQQFHKKSEDKAITHYLKGLKLEEKSFAWRKLLTALEKVAERRVRQNVRLVESTSLLGLVFKLKGQEMKALLYYEKALRLSGEMNPAF", "length": 488 }, "evidence": [ { "id": "E7FCM5", "url": "https://omabrowser.org/oma/group/E7FCM5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5T764-1", "protein_name": "Protein IFIT1 homolog B", "gene_name": "IFIT1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSEESDGKLIEDSLIQLRCHFTWKLLIEAPEIPDLENRIWEEIQFLDTKYNVGIHNLLAYVKHLKGQNEEALVSLKKAEDLIQKEHANQADIRSLVTWGNFAWVYYHMGRLAEAQTYLDKVENTCKKFANPSRYRMECPEVDCEEGWALAKCGGKNYERAKTCFEKALEGNPENPEFNTGYAITVYRLDKFNTASGRNKAFSLHVLKRAVRLNPDDVYIRVLLALKLQDEGQEAEGEKYIEEALTSISSQAYVFQYAAKFYRRKGSVDKALELLKMALETTPTSAFLHHQMGLCYRAQMIQIKEATNWQPRGQDRETVDRLVQLAICKFEKTIMLKRTFEMAYVDLAETYAEIGHHRKAEEHFQKGLRMKIFEDQLKQEIHYHYGRFQEHHGKSQDKAITHYLKGLKIEKMSHSREKLLNALEKLAKRCIHQNVRVVESVSLLGLIHKLKGEVSDALLCYERALRLAADLNPIF", "length": 474 }, "evidence": [ { "id": "E7FCM5", "url": "https://omabrowser.org/oma/group/E7FCM5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q64282-1", "protein_name": "Antiviral innate immune response effector IFIT1", "gene_name": "Ifit1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGENADGDQVMENLLQLRCHFTWKLLFENNDIPDLEVRISEQVQFLDIKNPLGMHNLLAYVRHLKGQQDEALQSLKEAEALIQSEQLSKRSLATWGNCAWLHYHRGSLAEAQIYLDKVEKVCKEFSSPFRYRLECAEMDCEEGWALLKCGGGNYKQAMACFAKALKVEPENPEYNTGYAVVAYRQDLDDNFISLEPLRKAVRLNPEDPYLKVLLALKLQDLGEHVEAEAHIEEALSSTSCQSYVIRYAAKYFRRKHRVDKALHLLNRALQASPSSGYLHYQKGLCYKQQISQLRTSRNRQPRRQDNVQELAQQAIHEFQETLKLRPTFEMAYVCMAEVQAEIHQYEEAERNFQKALNNKTLVAHIEQDIHLRYGRFLQFHKQSEDKAITLYLKGLKVEEKSFAWRKLLTALEKVAERRVCQNVHLVESTSLLGLVYKLKGQEKNALFYYEKALRLTGEMNPAF", "length": 463 }, "evidence": [ { "id": "E7FCM5", "url": "https://omabrowser.org/oma/group/E7FCM5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "response to other organism", "id": "GO:0051707", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051707", "evidence": [ { "database": "UniProtKB", "id": "E7FCM5", "url": "https://www.uniprot.org/uniprotkb/E7FCM5" } ], "pmid": "" }, { "name": "cellular response to cytokine stimulus", "id": "GO:0071345", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071345", "evidence": [ { "database": "UniProtKB", "id": "E7FCM5", "url": "https://www.uniprot.org/uniprotkb/E7FCM5" } ], "pmid": "" }, { "name": "antiviral innate immune response", "id": "GO:0140374", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140374", "evidence": [ { "database": "UniProtKB", "id": "E7FCM5", "url": "https://www.uniprot.org/uniprotkb/E7FCM5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E7FCM5", "url": "https://www.uniprot.org/uniprotkb/E7FCM5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E7FCM5", "url": "https://www.uniprot.org/uniprotkb/E7FCM5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 417, "end_pos": 419, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 113, "end_pos": 115 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 417, "end_pos": 419 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7FGS2-1", "uniprot_ac": "E7FGS2", "uniprot_id": "E7FGS2_DANRE", "mass": { "chemical_mass": 29068.0, "monoisotopic_mass": 29068.0 }, "refseq": { "ac": "NP_001313526", "name": "uncharacterized protein LOC792958", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313526" }, "gene_names": [ { "name": "ncoa7a", "type": "recommended", "evidence": [ { "id": "E7FGS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FGS2" } ] }, { "name": "ncoa7a", "type": "synonym", "evidence": [ { "id": "NP_001313526", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313526" } ] } ], "protein_names": [ { "name": "C2H2-type zinc finger protein", "type": "synonym", "evidence": [ { "id": "NP_001313526", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313526" } ] }, { "name": "Uncharacterized protein LOC792958", "type": "synonym", "evidence": [ { "id": "E7FGS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FGS2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC792958", "type": "synonym", "evidence": [ { "id": "NP_001313526", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313526" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01024702.1, SRR32588727.1446715.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898401, SAMEA898404 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001313526", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313526" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FGS2", "url": "https://www.uniprot.org/uniprotkb/E7FGS2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ncoa7a", "url": "https://www.uniprot.org/uniprotkb/E7FGS2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-200102-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-200102-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077559", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077559", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "792958", "url": "https://www.ncbi.nlm.nih.gov/gene/792958", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006571", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006571", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:792958", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:792958", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MPPRTQG", "url": "https://omabrowser.org/oma/group/MPPRTQG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BHI8", "url": "https://www.orthodb.org/?gene=A0A8M2BHI8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FGS2", "url": "https://www.orthodb.org/?gene=E7FGS2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23354", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23354", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23354:SF68", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23354:SF68", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07534", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07534", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001313526", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313526", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BHI8", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BHI8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BHI8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BHI8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHM0", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HHM0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HHM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FGS2", "url": "https://www.uniprot.org/uniprotkb/E7FGS2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FGS2-1", "url": "https://www.uniprot.org/uniprotkb/E7FGS2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-200102-1", "url": "https://zfin.org/ZDB-GENE-200102-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGVAYSVGEVDHLYTFFVEWSPENIYSHKHSRKQQEFLQVHPDALSVIGSLLKDSPPENWQIVSVKQQKRRTSVCSSADSESDDLLPVLINHSQILKELHLEQLMSHIPARAQGNQWKLVYSTAVHGTSLRTLYRQMAELDRPVLMVIRDTDGQVFGAFSSDPFRVSSYCYGTGETFLYSFSPEFQVFRWTGENSYFVRGFLDSLQMGGGGGPFGLWLDADLYRGSSYSCNTFCNRPLSLHHDFTVQELEVWSFV", "length": 255, "header": "tr|E7FGS2-1|E7FGS2_DANRE Isoform 1 of Uncharacterized protein LOC792958 OS=Danio rerio OX=7955 GN=ncoa7a PE=4 SV=1 CANONICAL=E7FGS2-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BHI8-1", "url": "https://www.uniprot.org/uniprotkb/E7FGS2/entry#A0A8M2BHI8-1", "sequence": { "sequence": "MRKQQSVQILYFANGSDGPFVEIVSVKQQKRRTSVCSSADSESDDLLPVLINHSQILKELHLEQLMSHIPARAQGNQWKLVYSTAVHGTSLRTLYRQMAELDRPVLMVIRDTDGQVFGAFSSDPFRVSSYCYGTGETFLYSFSPEFQVFRWTGENSYFVRGFLDSLQMGGGGGPFGLWLDADLYRGSSYSCNTFCNRPLSLHHDFTVQELEVWSFV", "length": 216, "header": "tr|A0A8M2BHI8-1|E7FGS2_DANRE Computationally mapped isoform of Uncharacterized protein LOC792958 OS=Danio rerio OX=7955 GN=ncoa7a PE=4 SV=1 CANONICAL=E7FGS2-1" }, "locus": {} }, { "isoform_ac": "A0AC58HHM0-1", "url": "https://www.uniprot.org/uniprotkb/E7FGS2/entry#A0AC58HHM0-1", "sequence": { "sequence": "MSHIPARAQGNQWKLVYSTAVHGTSLRTLYRQMAELDRPVLMVIRDTDGQVFGAFSSDPFRVSSYCYGTGETFLYSFSPEFQVFRWTGENSYFVRGFLDSLQMGGGGGPFGLWLDADLYRGSSYSCNTFCNRPLSLHHDFTVQELEVWSFV", "length": 151, "header": "tr|A0AC58HHM0-1|A0AC58HHM0_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=ncoa7a PE=4 SV=1 CANONICAL=E7FGS2-1" }, "locus": {} }, { "isoform_ac": "E7FGS2-1", "url": "https://www.uniprot.org/uniprotkb/E7FGS2/entry#E7FGS2-1", "sequence": { "sequence": "MGVAYSVGEVDHLYTFFVEWSPENIYSHKHSRKQQEFLQVHPDALSVIGSLLKDSPPENWQIVSVKQQKRRTSVCSSADSESDDLLPVLINHSQILKELHLEQLMSHIPARAQGNQWKLVYSTAVHGTSLRTLYRQMAELDRPVLMVIRDTDGQVFGAFSSDPFRVSSYCYGTGETFLYSFSPEFQVFRWTGENSYFVRGFLDSLQMGGGGGPFGLWLDADLYRGSSYSCNTFCNRPLSLHHDFTVQELEVWSFV", "length": 255, "header": "tr|E7FGS2-1|E7FGS2_DANRE Isoform 1 of Uncharacterized protein LOC792958 OS=Danio rerio OX=7955 GN=ncoa7a PE=4 SV=1 CANONICAL=E7FGS2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "E7FGS2", "url": "https://www.uniprot.org/uniprotkb/E7FGS2" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity.", "journal": "J. Immunol.", "date": "2019", "authors": "Levraud Jean-Pierre, Jouneau Luc, Briolat Val\u00e9rie, Laghi Valerio, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "E7FGS2", "url": "https://www.uniprot.org/uniprotkb/E7FGS2" } ], "reference": [ { "type": "PubMed", "id": "31732531", "url": "https://glygen.org/publication/PubMed/31732531" } ] } ], "pathway": [ { "id": "dre:792958", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:792958", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "E7FGS2", "url": "https://www.uniprot.org/uniprotkb/E7FGS2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7FGS2", "url": "https://www.uniprot.org/uniprotkb/E7FGS2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E7FGS2", "url": "https://www.uniprot.org/uniprotkb/E7FGS2" } ], "pmid": "" }, { "name": "response to oxidative stress", "id": "GO:0006979", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006979", "evidence": [ { "database": "UniProtKB", "id": "E7FGS2", "url": "https://www.uniprot.org/uniprotkb/E7FGS2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": 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The reference sequence was derived from JBMGRA010000007.1. On or before Jun 16, 2015 this sequence version replaced XP_005172264.1, NP_001070612.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001070612", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070612" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F115", "url": "https://www.uniprot.org/uniprotkb/E7F115" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmem88b", "url": "https://www.uniprot.org/uniprotkb/E7F115", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060929-644", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-644", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000069388", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000069388", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100004517", "url": "https://www.ncbi.nlm.nih.gov/gene/100004517", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033355", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033355", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100004517", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004517", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HTNHHQH", "url": "https://omabrowser.org/oma/group/HTNHHQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BJJ4", "url": "https://www.orthodb.org/?gene=A0A8M2BJJ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F115", "url": "https://www.orthodb.org/?gene=E7F115", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28628", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28628", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28628:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28628:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27917", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27917", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001070612", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001070612", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BJJ4", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BJJ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BJJ4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BJJ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F115", "url": "https://www.uniprot.org/uniprotkb/E7F115", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F115-1", "url": "https://www.uniprot.org/uniprotkb/E7F115-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060929-644", "url": "https://zfin.org/ZDB-GENE-060929-644", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRLTYQGLQQGKIRMSMNDTLEKGAHHQTIDLSEELPSISHHHQHHHPNLQHTNSLASTLPAGTAVGGSAVVVPPPYSPEAGGSEAPLELRGSLDCWACSVLVTAQNLLIAAINACLAGLVFGLILTPAIVMVVFGFLCHSTVRPHGSIPYCSDLLTDGGCVALLVVGFLLVTPLLVLALAAYCRLARHLQLGLCFIPYSRAVYKNLPATQHCGLAGGCCGQRSMKGAGKGKVWV", "length": 235, "header": "tr|E7F115-1|E7F115_DANRE Isoform 1 of Transmembrane protein 88b OS=Danio rerio OX=7955 GN=tmem88b PE=3 SV=2 CANONICAL=E7F115-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BJJ4-1", "url": "https://www.uniprot.org/uniprotkb/E7F115/entry#A0A8M2BJJ4-1", "sequence": { "sequence": "MSMNDTLEKGAHHQTIDLSEELPSISHHHQHHHPNLQHTNSLASTLPAGTAVGGSAVVVPPPYSPEAGGSEAPLELRGSLDCWACSVLVTAQNLLIAAINACLAGLVFGLILTPAIVMVVFGFLCHSTVRPHGSIPYCSDLLTDGGCVALLVVGFLLVTPLLVLALAAYCRLARHLQLGLCFIPYSRAVYKNLPATQHCGLAGGCCGQRSMKGAGKGKVWV", "length": 221, "header": "tr|A0A8M2BJJ4-1|E7F115_DANRE Computationally mapped isoform of Transmembrane protein 88b OS=Danio rerio OX=7955 GN=tmem88b PE=3 SV=1 CANONICAL=E7F115-1" }, "locus": {} }, { "isoform_ac": "E7F115-1", "url": "https://www.uniprot.org/uniprotkb/E7F115/entry#E7F115-1", "sequence": { "sequence": "MRLTYQGLQQGKIRMSMNDTLEKGAHHQTIDLSEELPSISHHHQHHHPNLQHTNSLASTLPAGTAVGGSAVVVPPPYSPEAGGSEAPLELRGSLDCWACSVLVTAQNLLIAAINACLAGLVFGLILTPAIVMVVFGFLCHSTVRPHGSIPYCSDLLTDGGCVALLVVGFLLVTPLLVLALAAYCRLARHLQLGLCFIPYSRAVYKNLPATQHCGLAGGCCGQRSMKGAGKGKVWV", "length": 235, "header": "tr|E7F115-1|E7F115_DANRE Isoform 1 of Transmembrane protein 88b OS=Danio rerio OX=7955 GN=tmem88b PE=3 SV=2 CANONICAL=E7F115-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Comparative analysis of period genes in teleost fish genomes.", "journal": "J. Mol. Evol.", "date": "2008", "authors": "Wang Han", "evidence": [ { "database": "UniProtKB", "id": "E7F115", "url": "https://www.uniprot.org/uniprotkb/E7F115" } ], "reference": [ { "type": "PubMed", "id": "18535754", "url": "https://glygen.org/publication/PubMed/18535754" } ] }, { "title": "Udu deficiency activates DNA damage checkpoint.", "journal": "Mol. Biol. Cell", "date": "2009", "authors": "Lim Chiaw-Hwee, Chong Shang-Wei, Jiang Yun-Jin", "evidence": [ { "database": "UniProtKB", "id": "E7F115", "url": "https://www.uniprot.org/uniprotkb/E7F115" } ], "reference": [ { "type": "PubMed", "id": "19656853", "url": "https://glygen.org/publication/PubMed/19656853" } ] }, { "title": "Differential expression of neuroligin genes in the nervous system of zebrafish.", "journal": "Dev. Dyn.", "date": "2010", "authors": "Davey Crystal, Tallafuss Alexandra, Washbourne Philip", "evidence": [ { "database": "UniProtKB", "id": "E7F115", "url": "https://www.uniprot.org/uniprotkb/E7F115" } ], "reference": [ { "type": "PubMed", "id": "20063411", "url": "https://glygen.org/publication/PubMed/20063411" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7F115", "url": "https://www.uniprot.org/uniprotkb/E7F115" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Comparison of Zebrafish tmem88a mutant and morpholino knockdown phenotypes.", "journal": "PLoS ONE", "date": "2017", "authors": "Eve Alexander M J, Place Elsie S, Smith James C", "evidence": [ { "database": "UniProtKB", "id": "E7F115", "url": "https://www.uniprot.org/uniprotkb/E7F115" } ], "reference": [ { "type": "PubMed", "id": "28192479", "url": "https://glygen.org/publication/PubMed/28192479" } ] } ], "pathway": [ { "id": "dre:100004517", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004517", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3V7A2-1", "protein_name": "Transmembrane protein 88", "gene_name": "Tmem88", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEVPAAQRPGLAGAPEPRDPLDCWACAVLVTAQNLLVAVFNLLLLALVLGTILLPAVTMLGFGFLCHSQAPPCTAHLRDPGFTTLLVIGFLLLVPLLVLALATYRRLCLRLRLADCLVPYSRALYRRRRIPQPKQIPVSSSPRSVPTPGKVWV", "length": 154 }, "evidence": [ { "id": "MGI:1914270", "url": "https://alliancegenome.org/gene/MGI:1914270#orthology", "database": "AGR" }, { "id": "HGNC:32371", "url": "https://alliancegenome.org/gene/HGNC:32371#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6PEY1-1", "protein_name": "Transmembrane protein 88", "gene_name": 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"pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7EZX4-1", "uniprot_ac": "E7EZX4", "uniprot_id": "E7EZX4_DANRE", "mass": { "chemical_mass": 196319.0, "monoisotopic_mass": 196319.0 }, "refseq": { "ac": "XP_009301828", "name": "NACHT and WD repeat domain-containing protein 2 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301828" }, "gene_names": [ { "name": "nwd2", "type": "recommended", "evidence": [ { "id": "E7EZX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZX4" } ] }, { "name": "nwd2", "type": "synonym", "evidence": [ { "id": "XP_009301828", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301828" } ] } ], "protein_names": [ { "name": "NACHT and WD repeat domain-containing protein 2 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_009301828", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301828" }, { "id": "E7EZX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZX4/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009301828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301828" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZX4", "url": "https://www.uniprot.org/uniprotkb/E7EZX4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nwd2", "url": "https://www.uniprot.org/uniprotkb/E7EZX4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-161213-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-161213-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077162", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077162", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "562320", "url": "https://www.ncbi.nlm.nih.gov/gene/562320", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052752", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052752", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056534", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056534", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057588", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057588", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562320", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562320", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KHCGIGG", "url": "https://omabrowser.org/oma/group/KHCGIGG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2BK82", "url": "https://www.orthodb.org/?gene=A0A8M2BK82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7TEV6", "url": "https://www.orthodb.org/?gene=A0A8N7TEV6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7EZX4", "url": "https://www.orthodb.org/?gene=E7EZX4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR19871", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19871", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR19871:SF39", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR19871:SF39", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23586", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23586", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25469", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25469", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009301828", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301828", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2BK82", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BK82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2BK82-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2BK82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7TEV6", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEV6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7TEV6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TEV6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZX4", "url": "https://www.uniprot.org/uniprotkb/E7EZX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZX4-1", "url": "https://www.uniprot.org/uniprotkb/E7EZX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-161213-1", "url": "https://zfin.org/ZDB-GENE-161213-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MWPSGAGSRQPCPRESALRRAAISGNVLALPPFHVPTGRSVRVFICANPDDTEAERNALKEHVYPKLRDFCRENYGIEFQVVDLYWGIDPEEWDSPELQRLRMKLLEECLKTSAGPCFVGLIGEKYGSIRVPGEVESAEFEMILDAAVEAGLDTRILEEWYCRDENSVPPAYYLKPKAEMLKNYQNSMESNTVAKSKNDKAWRAVSEEIKRIFRTSVLQLQEKGTMKSGQAKKFLCSALEDELDFALGKQTPAFLKKCVCYIRKISNFDRFAKLPEMARYMDIVVSDDRVMRNQEAYERLLKVRDEFIPVVVAASNLRVYSSVTHCDMKLGYSQEVESHYVEGLCKQFYEDMVDIIQATVQQNFDTETDPLYDEIIQHLSLCKTFSSFYVYKSEALDIVQEYLYPSKGGRITPQVVYGGPCTGKTLLLAEVAKQAYSWIQKEMGPETDPVVIVRFIGSTDFSTDLRTLLQSICEQIAINYRCLIHFLPNKIQEMRELLVNLLGESSFHRPLVIILDALEQLSDADEARKLWWLPVHLPRTVRIVVSTLPNKHGILQKLRCLIHDEEAYVELMQRDRKACSQTLKQQLLGVKRKVTSGQQIYVNEAMAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGSRFVFRALGYITMARAGLTELELEDILSLDNSVLGDIMVSSNLKSPLRISYDFIARLKEELEGYLVERQVHNVTLMVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFHCDNNHFASLNISQHRNPHNQQSLHGHDKASADKHSYDRQTPEQPWVFQCNLLEPDIFFVNHRKMTELTYHLTRSGRTDDLMYGVIMNFSWLYTMIKIGQFDKALSDIDLAYSYTQEKELKFLATTLRSIKLKVTKNPASLSAELQQRLLPVVTSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSPERLPLSSSYMQIVETLPTLAPNIVIVALEDGSVSTWDVESRQLLRQIDTARSVVLGIRLTTDEKYLVVATTKNTLLIYDNHKSCLLSEVEVKGSKHCGITGGVAFINGFTLSSHHALAWLEASKDVSVIDLLYGWPLYQFHCWYEVTCVQCSPDGMYAFCGQYLNTTTIFHLGSGDKLATMTSEFSGGFVKSILILDTINQMVMIDNEGSLSVWSTKDITNPKLMEDYDCRGDDSEVVGIELSEDQRSILICKARSIEVLDTKIWKMAEKFKAKRTEKFVAAVLSKNSQSIIASMENTSSIFVWRRDSGQCMASLIEISGAIVKLIKSTHHNLLLSVASSGVLSVWDIDIITAMSNIDKTGKPIQILQLSGREDFVYTMDGSEVIHKWNYSTGFIEMVFKHEGLVENCVLTTSGDLMVTSDDKSSQYIWHTTTGENIFRINGQKISQLLITHNDQFVVSLCEQNASRVWRLATGHKVCNILVTLQHALITTANTFLVGANKNKLLAVSLWSGSVSKKFICDDGITIVNFKLIPDSPDFVVFITSTETVFIWSVADESVCRRVQLPNNFLKNLEDFQISPNGKLGIVSKGDENINVLDLHSGKLRLVHAAGIIWRQKLSRDGRYLVYICFRNCDEDDDAGVVSSLIVMRLADGKSIGTCSLYKTPTYLCLSQRALNIIVGFEDGSIGTYTVVDRVDAALKIKIATSNSRQIVNNASQKVRPKCSNNAFKTIADCVWRESTEVFSRDSPINVSDGGEPETTTPTKKTELLQ", "length": 1735, "header": "tr|E7EZX4-1|E7EZX4_DANRE Isoform 1 of NACHT and WD repeat domain-containing protein 2 isoform X2 OS=Danio rerio OX=7955 GN=nwd2 PE=4 SV=3 CANONICAL=E7EZX4-1" }, "isoforms": [ { "isoform_ac": "A0A8M2BK82-1", "url": "https://www.uniprot.org/uniprotkb/E7EZX4/entry#A0A8M2BK82-1", "sequence": { "sequence": "MILDAAVEAGLDTRILEEWYCRDENSVPPAYYLKPKAEMLKNYQNSMESNTVAKSKNDKAWRAVSEEIKRIFRTSVLQLQEKGTMKSGQAKKFLCSALEDELDFALGKQTPAFLKKCVCYIRKISNFDRFAKLPEMARYMDIVVSDDRVMRNQEAYERLLKVRDEFIPVVVAASNLRVYSSVTHCDMKLGYSQEVESHYVEGLCKQFYEDMVDIIQATVQQNFDTETDPLYDEIIQHLSLCKTFSSFYVYKSEALDIVQEYLYPSKGGRITPQVVYGGPCTGKTLLLAEVAKQAYSWIQKEMGPETDPVVIVRFIGSTDFSTDLRTLLQSICEQIAINYRCLIHFLPNKIQEMRELLVNLLGESSFHRPLVIILDALEQLSDADEARKLWWLPVHLPRTVRIVVSTLPNKHGILQKLRCLIHDEEAYVELMQRDRKACSQTLKQQLLGVKRKVTSGQQIYVNEAMAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGSRFVFRALGYITMARAGLTELELEDILSLDNSVLGDIMVSSNLKSPLRISYDFIARLKEELEGYLVERQVHNVTLMVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFHCDNNHFASLNISQHRNPHNQQSLHGHDKASADKHSYDRQTPEQPWVFQCNLLEPDIFFVNHRKMTELTYHLTRSGRTDDLMYGVIMNFSWLYTMIKIGQFDKALSDIDLAYSYTQEKELKFLATTLRSIKLKVTKNPASLSAELQQRLLPVVTSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSPERLPLSSSYMQIVETLPTLAPNIVIVALEDGSVSTWDVESRQLLRQIDTARSVVLGIRLTTDEKYLVVATTKNTLLIYDNHKSCLLSEVEVKGSKHCGITGGVAFINGFTLSSHHALAWLEASKDVSVIDLLYGWPLYQFHCWYEVTCVQCSPDGMYAFCGQYLNTTTIFHLGSGDKLATMTSEFSGGFVKSILILDTINQMVMIDNEGSLSVWSTKDITNPKLMEDYDCRGDDSEVVGIELSEDQRSILICKARSIEVLDTKIWKMAEKFKAKRTEKFVAAVLSKNSQSIIASMENTSSIFVWRRDSGQCMASLIEISGAIVKLIKSTHHNLLLSVASSGVLSVWDIDIITAMSNIDKTGKPIQILQLSGREDFVYTMDGSEVIHKWNYSTGFIEMVFKHEGLVENCVLTTSGDLMVTSDDKSSQYIWHTTTGENIFRINGQKISQLLITHNDQFVVSLCEQNASRVWRLATGHKVCNILVTLQHALITTANTFLVGANKNKLLAVSLWSGSVSKKFICDDGITIVNFKLIPDSPDFVVFITSTETVFIWSVADESVCRRVQLPNNFLKNLEDFQISPNGKLGIVSKGDENINVLDLHSGKLRLVHAAGIIWRQKLSRDGRYLVYICFRNCDEDDDAGVVSSLIVMRLADGKSIGTCSLYKTPTYLCLSQRALNIIVGFEDGSIGTYTVVDRVDAALKIKIATSNSRQIVNNASQKVRPKCSNNAFKTIADCVWRESTEVFSRDSPINVSDGGEPETTTPTKKTELLQ", "length": 1594, "header": "tr|A0A8M2BK82-1|E7EZX4_DANRE Computationally mapped isoform of NACHT and WD repeat domain-containing protein 2 isoform X2 OS=Danio rerio OX=7955 GN=nwd2 PE=4 SV=1 CANONICAL=E7EZX4-1" }, "locus": {} }, { "isoform_ac": "A0A8N7TEV6-1", "url": "https://www.uniprot.org/uniprotkb/E7EZX4/entry#A0A8N7TEV6-1", "sequence": { "sequence": "MKRMNPRWKSPPMWPSGAGSRQPCPRESALRRAAISGNVLALPPFHVPTGRSVRVFICANPDDTEAERNALKEHVYPKLRDFCRENYGIEFQVVDLYWGIDPEEWDSPELQRLRMKLLEECLKTSAGPCFVGLIGEKYGSIRVPGEVESAEFEMILDAAVEAGLDTRILEEWYCRDENSVPPAYYLKPKAEMLKNYQNSMESNTVAKSKNDKAWRAVSEEIKRIFRTSVLQLQEKGTMKSGQAKKFLCSALEDELDFALGKQTPAFLKKCVCYIRKISNFDRFAKLPEMARYMDIVVSDDRVMRNQEAYERLLKVRDEFIPVVVAASNLRVYSSVTHCDMKLGYSQEVESHYVEGLCKQFYEDMVDIIQATVQQNFDTETDPLYDEIIQHLSLCKTFSSFYVYKSEALDIVQEYLYPSKGGRITPQVVYGGPCTGKTLLLAEVAKQAYSWIQKEMGPETDPVVIVRFIGSTDFSTDLRTLLQSICEQIAINYRCLIHFLPNKIQEMRELLVNLLGESSFHRPLVIILDALEQLSDADEARKLWWLPVHLPRTVRIVVSTLPNKHGILQKLRCLIHDEEAYVELMQRDRKACSQTLKQQLLGVKRKVTSGQQIYVNEAMAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGSRFVFRALGYITMARAGLTELELEDILSLDNSVLGDIMVSSNLKSPLRISYDFIARLKEELEGYLVERQVHNVTLMVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFHCDNNHFASLNISQHRNPHNQQSLHGHDKASADKHSYDRQTPEQPWVFQCNLLEPDIFFVNHRKMTELTYHLTRSGRTDDLMYGVIMNFSWLYTMIKIGQFDKALSDIDLAYSYTQEKELKFLATTLRSIKLKVTKNPASLSAELQQRLLPVVTSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSPERLPLSSSYMQIVETLPTLAPNIVIVALEDGSVSTWDVESRQLLRQIDTARSVVLGIRLTTDEKYLVVATTKNTLLIYDNHKSCLLSEVEVKGSKHCGITGGVAFINGFTLSSHHALAWLEASKDVSVIDLLYGWPLYQFHCWYEVTCVQCSPDGMYAFCGQYLNTTTIFHLGSGDKLATMTSEFSGGFVKSILILDTINQMVMIDNEGSLSVWSTKDITNPKLMEDYDCRGDDSEVVGIELSEDQRSILICKARSIEVLDTKIWKMAEKFKAKRTEKFVAAVLSKNSQSIIASMENTSSIFVWRRDSGQCMASLIEISGAIVKLIKSTHHNLLLSVASSGVLSVWDIDIITAMSNIDKTGKPIQILQLSGREDFVYTMDGSEVIHKWNYSTGFIEMVFKHEGLVENCVLTTSGDLMVTSDDKSSQYIWHTTTGENIFRINGQKISQLLITHNDQFVVSLCEQNASRVWRLATGHKVCNILVTLQHALITTANTFLVGANKNKLLAVSLWSGSVSKKFICDDGITIVNFKLIPDSPDFVVFITSTETVFIWSVADESVCRRVQLPNNFLKNLEDFQISPNGKLGIVSKGDENINVLDLHSGKLRLVHAAGIIWRQKLSRDGRYLVYICFRNCDEDDDAGVVSSLIVMRLADGKSIGTCSLYKTPTYLCLSQRALNIIVGFEDGSIGTYTVVDRVDAALKIKIATSNSRQIVNNASQKVRPKCSNNAFKTIADCVWRESTEVFSRDSPINVSDGGEPETTTPTKKTELLQ", "length": 1747, "header": "tr|A0A8N7TEV6-1|E7EZX4_DANRE Computationally mapped isoform of NACHT and WD repeat domain-containing protein 2 isoform X2 OS=Danio rerio OX=7955 GN=nwd2 PE=4 SV=1 CANONICAL=E7EZX4-1" }, "locus": {} }, { "isoform_ac": "E7EZX4-1", "url": "https://www.uniprot.org/uniprotkb/E7EZX4/entry#E7EZX4-1", "sequence": { "sequence": "MWPSGAGSRQPCPRESALRRAAISGNVLALPPFHVPTGRSVRVFICANPDDTEAERNALKEHVYPKLRDFCRENYGIEFQVVDLYWGIDPEEWDSPELQRLRMKLLEECLKTSAGPCFVGLIGEKYGSIRVPGEVESAEFEMILDAAVEAGLDTRILEEWYCRDENSVPPAYYLKPKAEMLKNYQNSMESNTVAKSKNDKAWRAVSEEIKRIFRTSVLQLQEKGTMKSGQAKKFLCSALEDELDFALGKQTPAFLKKCVCYIRKISNFDRFAKLPEMARYMDIVVSDDRVMRNQEAYERLLKVRDEFIPVVVAASNLRVYSSVTHCDMKLGYSQEVESHYVEGLCKQFYEDMVDIIQATVQQNFDTETDPLYDEIIQHLSLCKTFSSFYVYKSEALDIVQEYLYPSKGGRITPQVVYGGPCTGKTLLLAEVAKQAYSWIQKEMGPETDPVVIVRFIGSTDFSTDLRTLLQSICEQIAINYRCLIHFLPNKIQEMRELLVNLLGESSFHRPLVIILDALEQLSDADEARKLWWLPVHLPRTVRIVVSTLPNKHGILQKLRCLIHDEEAYVELMQRDRKACSQTLKQQLLGVKRKVTSGQQIYVNEAMAKCTLPMFVNLIYREVVHWRSHKDVDDKSLCSTVHESIEQLFYSVENKLGSRFVFRALGYITMARAGLTELELEDILSLDNSVLGDIMVSSNLKSPLRISYDFIARLKEELEGYLVERQVHNVTLMVWANRHLHLIAQKLYLSNEEDVHQMHSLLAEYFLGAWAGGRKKIFHCDNNHFASLNISQHRNPHNQQSLHGHDKASADKHSYDRQTPEQPWVFQCNLLEPDIFFVNHRKMTELTYHLTRSGRTDDLMYGVIMNFSWLYTMIKIGQFDKALSDIDLAYSYTQEKELKFLATTLRSIKLKVTKNPASLSAELQQRLLPVVTSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSPERLPLSSSYMQIVETLPTLAPNIVIVALEDGSVSTWDVESRQLLRQIDTARSVVLGIRLTTDEKYLVVATTKNTLLIYDNHKSCLLSEVEVKGSKHCGITGGVAFINGFTLSSHHALAWLEASKDVSVIDLLYGWPLYQFHCWYEVTCVQCSPDGMYAFCGQYLNTTTIFHLGSGDKLATMTSEFSGGFVKSILILDTINQMVMIDNEGSLSVWSTKDITNPKLMEDYDCRGDDSEVVGIELSEDQRSILICKARSIEVLDTKIWKMAEKFKAKRTEKFVAAVLSKNSQSIIASMENTSSIFVWRRDSGQCMASLIEISGAIVKLIKSTHHNLLLSVASSGVLSVWDIDIITAMSNIDKTGKPIQILQLSGREDFVYTMDGSEVIHKWNYSTGFIEMVFKHEGLVENCVLTTSGDLMVTSDDKSSQYIWHTTTGENIFRINGQKISQLLITHNDQFVVSLCEQNASRVWRLATGHKVCNILVTLQHALITTANTFLVGANKNKLLAVSLWSGSVSKKFICDDGITIVNFKLIPDSPDFVVFITSTETVFIWSVADESVCRRVQLPNNFLKNLEDFQISPNGKLGIVSKGDENINVLDLHSGKLRLVHAAGIIWRQKLSRDGRYLVYICFRNCDEDDDAGVVSSLIVMRLADGKSIGTCSLYKTPTYLCLSQRALNIIVGFEDGSIGTYTVVDRVDAALKIKIATSNSRQIVNNASQKVRPKCSNNAFKTIADCVWRESTEVFSRDSPINVSDGGEPETTTPTKKTELLQ", "length": 1735, "header": "tr|E7EZX4-1|E7EZX4_DANRE Isoform 1 of NACHT and WD repeat domain-containing protein 2 isoform X2 OS=Danio rerio OX=7955 GN=nwd2 PE=4 SV=3 CANONICAL=E7EZX4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:562320", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562320", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZT1-1", "protein_name": "NACHT and WD repeat domain-containing protein 2", "gene_name": "Nwd2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWPAGAGTKQLCARDSALRRAAFSGNLTALPSHLVPAGRSVRVFISANPEDTGAERQALRETVYPKLREFCRENYGLEFQVIDLYWGVEEDEWDSPELQKMRMKLLEECLKSSAGPCFVRAVGVNCLADTQGLLGEKYGNIRIPGQVEASEFEMILDAAVEAKLETKLLEDWYCRDENSVPAAYYLRPRLEVPRTNKNSTQPSATGEHERPWQEISDEIKTIFKAATKLLHEQGKMKLSQAKRYLFSAIEDEFDFALGKQTPAFLKKCVCYIRKIANIERFVKIPEMGKYMDITGTDPRIIRDPEAQEKLIKLRDEFIPTIVASSNLRVYTSVTHCDMKLGYSQEIENHYIEGLGKQFYEDMIDIIQATVQQNFDTETDTLYDEILQHSSLCKTYASFYEYKCESLNILHKYILPSKTGHINPLIVYGGPCTGKTLLLAEVAKKAYGWLHEDTGPDSDPVVIVRFLGTTDMSIDLRTLLLSVCEQLAVNYRCLVQSFPKKIHDLRDLFINLLNESSLQRPLVIIFDALEQLSETDEARKLWWLPAHLPRFVRIILSTLPNKHGILQKLRCLIHEEDNYIELIPRDRKMCSQVLKHQLLRVKRKVTSGQQIYVNNAFSKCTLPMFVNLTFREVRHWRSHKDVNESSLCVTVHESIEQLFWSLEKKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMNELIENTRPSNPLRVPYLYIARLKEGLNGYLIERHVKNVTLLVWANRHLQLIAQKLYLQEDSNLREMHTILADYFLGVWSGGRRKAFCLEDPYLNGCLDLENRSLLEEEKHFIEQASFDRQAPDQPWVFQCNPLEPDIFFVNHRKMSELLYHLTRCGKTDDLLYGIIMNFSWLYTMIKIGQFDKVLADIELAYNYSQEKELKFLASTLRGIRNKVITFPGSLSAELQQRLLPVVSSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSPERLPLASSHLHVTEILPTCNPSTVLTALENGSISTWDVETRQLLRQITTAQSVILGMKLTSDEKYLVVATTNNTLLIYDNVNSCLLSEVEIKGTKHGSSPTYINGFTLSINHALAWLEASKDVTVIDLLYGWPLYQFHCWYEVTCVQCSLDGVYAFCGQYLNNTTIFHLGSGEKICTVTSEFSGGFVKFLLILDTAQEMVMIDSEGSLSVWNTEDISSPQLTEDFDCRKEDSEVVSIELSEDQSAILICKALSIELLDTGMWKVAEKFRARHNERFISAVLSKNGDCIIATMENTPAVFFWRRDTGQCMASLKEISGTIVKLVKSSHHNMLLSLSTSGVLSIWDIDIITAMSNIDKTGKPIQSLVLPARGEIIYSLDGSDCVHKWNFSSGFIEAVFKHEGIVEHCVLTSAGDIMVTSDDKSSQYVWHTSSGENLFRINGQRISQLLITHNDQFVVSLCEENASRVWRLATGHRVCNILTTLQNAFITSANTFVVGMTKSKVLAVSLWTGSITKKFCCEDGITIVNFKLIPDCPDIIVFITSAETVNLWSLTDEVICRRVQLPSNFLKNLEDFEISPNGKLGIISRGDENINVLDLHSGKLRVVHASGVIWRQRLSRDGRYLVYICFQNGEEEEENDTVSSLIVMRLADGKNIGACSLYKTPTFLALSQRHLNIIVGFDDGSIGIYTVVDRVDAALKIKIATSNSRQIFSNATQTSRPKSNSYSFKVSVDCLWRESTEVFARDSPITVSDSSESNEATPSKKHNSCYDRVCAALESRSHSYTSDN", "length": 1754 }, "evidence": [ { "id": "E7EZX4", "url": "https://omabrowser.org/oma/group/E7EZX4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MNF4-1", "protein_name": "NACHT and WD repeat domain-containing protein 2", "gene_name": "NWD2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWPAGAGTKLPCPRDSALRRAAFSGNLTALPSHLVPAGRSVRVFISANPEDTGAERQALKENVYPKLREFCRENYGLEFQVIDLYWGVHEDEWDSPELQKTRMKLLEDCLKTSAGPCFVGLLGEKYGNIRIPGEVEASEFEMILDAAIEAKLDTKLLEEWYCRDENSVPAAYYLRPKSEMLKSNTNAMQPSANAENEKTWQEISDEIKKIFKTAVKLLHEKGKMKHSQAKRYLFSAIEDEFDFALGKQTPAFLKKCVCYIRKIANIERFVKIPEMGKYMDITGTEPRIIRDPEAQEKLIKLRDEFIPTIVASSNLRVYTSVTHCDMKLGYSQEIENHYIEGLGKQFYEDMIDIIQATVQQNFDTETDTLYDEILQHSSLCKTYASFYEYKCESLNIVHKYILPSKTGHINPLIVYGGPCTGKTLLLAEVAKKAYGWLHEDTGPESDPVVVVRFLGTTDLSTDLKSLLLSVCEQLAVNYRCLVQSYPKKIHDLRDLFINLLNESSLQRPLVVIFDALEQLSESDEARKLWWLPVHLPRFVRIVLSTLPNKHGILQKLRCLIHEEDNYIELIPRDRKMCSQVLKHQLLRVKRKVTSGQQIYVNNAFSKCTLPMFVNLTFREVRHWRSHRDVDESSLCVTVHESIEQLFWSLERKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMNELNENTRPSNPLRVPYLYIAKLKEGLSGYLIERHVKNVTLLVWANRHLQLIAQKLYLQDKSDLHEMHTILADYFLGVWSGGRRKAFCLEDPYLNGCLDLESRSLLEEERHFMEQASFDRQAPDQPWVFQCNPLEPDIFFVNHRKMCELLYHLTRCGKTDDLLYGIIMNFSWLYTMIKIGQFDKVLADIELAYIYSQEKELKFLASTLRSIKTKVVAFPGSLSAELQQRLLPVVSSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSPERLPLSSSHLHVTEILPTCNPSTVLTALENGSISTWDVETRQLLRQITTAQSVILGMKLSNDEKYLVVATTNNTLLVYDNVNSCLLSEVEIKGTKHGSGSTYINGFTLSVKHALAWLEASKDVTVIDLLYGWPLYQFHCWYEVTCVQCSLDGVYAFCGQYLNTTTIFHLGSGEKLCTVTSEFSGGFVKFLLILDTAQEMVMVDSEGSLSVWNTEDISNPQLTDDFDCRREDSEVVSIELSEDQSAVLICKALSIELLDTGLWKVAEKFRAKHNERFISAVLSKNGDCIIATMENTSAVFFWRRDTGQCMASLQEISGTIVKLVKSSHHNMLLSLSTSGVLSIWDIDIITAMSNIDKTGKPIQSLVLPARGEIIYSLDGSDCVHKWNFSSGFLEAVFKHEGTVEHCVLTSSGDVMVTSDDKSSQYVWHTSSGENLFRINGQRISQLLITHNDQFVVSLCEENASRVWRLATGHRVCNILTSLQNAFITSANTFVVGMTKSKVLAVSLWTGSITKKFCCEDGTTIVNFKLIPDCPDIIVFITSAETVNIWSLTEEVICRRVQLPNNFLKNLEDFEISPNGKLGIISRGDENINVLDLHSGKLRVVHASGVIWRQRLSRDGRYLVYICFRNGEEEDENGAISSLIVMRLADGKNIGACSLYKTPTFLALSQRHLNIIVGFDDGSIGIYTVVDRVDAALKIKIATSNSRQIFNNATQTSRPKCNSYCFKVSVDCLWRESTEVFARDSPITVSDSSEPNESTPSKKHNSCYERVCSALESRGHSYAPDN", "length": 1742 }, "evidence": [ { "id": "E7EZX4", "url": "https://omabrowser.org/oma/group/E7EZX4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6P5U7-1", "protein_name": "NACHT and WD repeat domain-containing protein 2", "gene_name": "Nwd2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWPAGAGTKLPCPRDSALRRAAFSGNLTALPSHLVPAGRSVRVFISANPEDTGAERQALRETVYPKLREFCRENYGLEFQVIDLYWGIEEDEWDSPELQKMRMKLLEECLKTSAGPCFVGLLGEKYGNIRIPGEVEASEFEMILDAAVEAKLETKLLEDWYCRDENSVPAAYYLRPRLEVPRSNKNSTQPSASSEQERPWQEISDEIKTIFKAAVKLLHEQGKMKQSQAKRYLFSAIEDEFDFALGKQTPAFLKKCVCYIRKIANIERFVKIPEMGKYMDITGTDPRIVRDPEAQEKLIKLRDEFIPTIVASSNLRVYTSVTHCDMKLGYSQEIENHYIEGLGKQFYEDMIDIIQATVQQNFDTETDTLYDEILQHSSLCKTYASFYEYKCESLNILHKYILPSKTGHINPLVVYGGPCTGKTLLLAEVAKKAYGWLHEDTGPDSDPVVIVRFLGTTDMSIDLRTLLLSVCEQLAVNYRCLVQSFPKKIHDLRDLFINLLNESSLQRPLVIILDALEQLSEADEARKLWWLPAHLPRFVRIILSTLPNKHGILQKLRCLIHEEDNYIELIPRDRKMCSQVLKHQLLRVKRKVTSGQQIYVNNAFSKCTLPMFVNLTFREVRHWRSHKDVDESSLCVTVHESIEQLFWSLEKKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMNELNENTRPSNPLRVPYLYIARLKEGLNGYLIERHVKNVTLLVWANRHLQLIAQKLYLQEDSNLREMHTILADYFLGVWSGGRRKAFCLEDPYLNGCLDLENRSLLEEEKHFMEQASFDRQAPDQPWVFQCNPLEPDIFFVNHRKMSELLYHLTRCGKTDDLLYGIIMNFSWLYTMIKIGQFDKVLADIELAYNYSQEKELKFLASTLRSIRNKVIAFPGSLSAELQQRLLPVVSSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSPERLPLASSHLHVTEILPTCNPSTVLTALENGSISTWDVETRQLLRQITTAQSVILGMKLSSDEKYLVVATTNNTLLIYDNVNSCLLSEVEIKGTKHGSGSTYINGFTLSVNHALAWLEASKDVTVIDLLYGWPLYQFHCWYEVTCVQCSLDGVYAFCGQYLNNTTIFHLGSGEKICTVTSEFSGGFVKFLLILDTAQEMVMVDSEGSLSVWNTEDISNPQLTEDFDCRKEDSEVVSIELSEDQSAILICKALSIELLDTGMWKVAEKFRARHNERFVSAVLSKNGDCIIATMENTPAVFFWRRDTGQCLASLQESSGTIVKLVKSSHHNMLLSLSTSGVLSIWDIDIITAMSNIDKTGKPIQSLVLPARGEIIYSLDGSDCVHKWNFSSGFIEAVFKHEGIVEHCVLTSTGDLMVTSDDKSSQYVWHTSSGENLFRINGQRISQLLITHNDQFVVSLCEENASRVWRLATGHRVCNILTTLQNAFITSANTFVVGMTKSKVLAVSLWTGSITKKFCCEDGITIVNFKLIPDCPDVIVFITSAETVNLWSLTDEVICRRVQLPSNFLKNLEDFEISPNGKLGIISRGDENINVLDLHSGKLRVVHASGVIWRQRLSRDGRYLVYICFRNGEEEEENDAISSLIVMRLADGKNIGACSLYKTPTFLALSQRHLNIIVGFDDGSIGIYTVVDRVDAALKIKIATSNSRQIFNNATQTSRPKSNSYSFKVSVDCLWRESTEVFARDSPITVSDSSESNEATPSKKHNSCYDRVCAALESRSHSYTPDN", "length": 1742 }, "evidence": [ { "id": "E7EZX4", "url": "https://omabrowser.org/oma/group/E7EZX4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9ULI1-1", "protein_name": "NACHT and WD repeat domain-containing protein 2", "gene_name": "NWD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWPAGAGTKLPCPRDSALRRAAFSGNLTALPSHLVPAGRSVRVFISANPEDTGAERQALRENVYPKLREFCRENYGLEFQVIDLYWGVEEDEWDSPELQKTRMKLLENCLKTSAGPCFVGLLGEKYGNIRIPGEVEASEFEMILDAAIEAKLETKLLEEWYCRDENSVPAAYYLRPKSEMLRSNRNAMQPSTNAENEKTWQEISDEIKKIFKAAVKLLHEKGKMKHSQAKRYLFSAIEDEFDFALGKQTPAFLKKCVCYIRKIANIERFVKIPEMGKYMDITGTEPRIIRDPEAQEKLIKLRDEFIPTIVASSNLRVYTSVTHCDMKLGYSQEIENHYIEGLGKQFYEDMIDIIQATIQQNFDTETDTLYDEILQHSSLCKTYASFYEYKCESLNIVHNYILPSKAGHINPLIIYGGPCTGKTLLLAEVAKKAYGWLHEDTGPESDPVVIVRFLGTTDMSSDLRTLLLSVCEQLAVNYRCLVQSYPKKIHDLCDLFINLLNESSLQRPLVIIFDALEQLSENDDARKLWWLPAHLPRFVRIVLSTLPNKHGILQKLRCLIHEEDNYIELIPRDRKMCSQVLKHQLLRVKRKVTSGQQIYVNNALSKCTLPMFVNLTFREVRHWRSHKDVDESSLSVTVHESIEQLFWSLEKKCGQKLVSRALGYITMAKMGLSEMELEDVLALDNSVMSELKENTRPSNPLRVPYLYIARLKEGLSGYLIERHVKNVTLLVWANRHLQLIAQKLYLQDDNDLREMHTILADYFLGVWSGGRRKAFCLEDPYLNGCLDLENRSLLEEEKHFMEQASFDRQAPDQPWVFQCNPLEPDIFFVNHRKMSELLYHLTRCGKTDDLLYGIIMNFSWLYTMIKIGQFDKVLSDIELAYNYSQEKELKFLANTLRSIKNKVTAFPGSLSAELQQRLLPVVSSLPKLRHLLLECDKDGPKYCSIVPLHSSMDVTYSPERLPLSSSHLHVTEILPTCNPSTVLTALENGSISTWDVETRQLLRQITTAQSVILGMKLTSDEKYLVVATTNNTLLIYDNVNSCLLSEVEIKGTKHGSSATYINGFTLSANHALAWLEASKDVTVIDLLYGWPLYQFHCWYEVTCVQCSLDGLYAFCGQYLNTTTIFHLGSGEKLCTVTSEFSGGFVKFLLILDTAQEMVMVDSEGSLSVWNTEDISSPQLTDDFDCRREDSEVVSIELSEDQSAVLICKALSIELLDTGLWKVAEKFRAKHNERFISAVLSKNGDCIIATMENTSAVFFWRRDTGQCMASLQEISGSIVKLVKSSHHNMLLSLSTSGVLSIWDIDIITAMSNIDKTGKPIQSLLLPARGEIIYSLDGSDCVHKWNFSSGFIEAVFKHEGIVEHCVLTSTGDIMVTSDDKSSQYVWHTSSGENLFRINGQRISQLLITHNDQFVVSLCEENASRVWRLATGHRVCNILTTLQNAFITSANTFVVGMTKSKVLAVSLWTGSITKKFCCEDGTTIVNFKLIPDCPDIIVFITSAETVNIWSLTDEVICRRVQLPNNFLKNLEDFEISPNGKLGIIARGDENINVLDLYSGKLRVVHASGIIWRQRLSRDGRYLVYICFRNGEEEDENGAIFSLIVMRLADGKNIGACSLYKTPTFLALSQRHLNIIVGFDDGSIGIYTVVDRVDAALKIKIATSNSRQIFNNATHTSRPKCNSYCFKISVDCLWRESTEVFARDSPITVSDSTESNEATPSKKHNSCYERVCSALEARGHSYAPDN", "length": 1742 }, "evidence": [ { "id": "E7EZX4", "url": "https://omabrowser.org/oma/group/E7EZX4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1131, "end_pos": 1133, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1263, "end_pos": 1265, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1355, "end_pos": 1357, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1430, "end_pos": 1432, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1679, "end_pos": 1681, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1715, "end_pos": 1717, "annotation": "n_glycosylation_sequon" }, { "start_pos": 728, "end_pos": 730, "annotation": "n_glycosylation_sequon" }, { "start_pos": 788, "end_pos": 790, "annotation": "n_glycosylation_sequon" }, { "start_pos": 865, "end_pos": 867, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EZX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZX4" }, { "id": "PF25469", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25469" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NWD1/2-like winged helix-turn-helix", "eco_id": "ECO_0000259", "start_pos": 638, "end_pos": 754, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7EZX4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZX4" }, { "id": "PF23586", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23586" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NWD2 C-terminal beta-propeller", "eco_id": "ECO_0000259", "start_pos": 1322, "end_pos": 1653, "start_aa": "Asn", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1131, "end_pos": 1133 }, { "start_pos": 1263, "end_pos": 1265 }, { "start_pos": 1355, "end_pos": 1357 }, { "start_pos": 1430, "end_pos": 1432 }, { "start_pos": 1679, "end_pos": 1681 }, { "start_pos": 1715, "end_pos": 1717 }, { "start_pos": 728, "end_pos": 730 }, { "start_pos": 788, "end_pos": 790 }, { "start_pos": 865, "end_pos": 867 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EZQ7-1", "uniprot_ac": "E7EZQ7", "uniprot_id": "E7EZQ7_DANRE", "mass": { "chemical_mass": 204413.0, "monoisotopic_mass": 204413.0 }, "refseq": { "ac": "XP_003200246", "name": "uncharacterized protein nacad isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200246" }, "gene_names": [ { "name": "nacad", "type": "recommended", "evidence": [ { "id": "E7EZQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7" } ] }, { "name": "nacad", "type": "synonym", "evidence": [ { "id": "XP_003200246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200246" } ] } ], "protein_names": [ { "name": "Uncharacterized protein nacad isoform X1", "type": "synonym", "evidence": [ { "id": "E7EZQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein nacad isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003200246", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200246" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003200246.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003200246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200246" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZQ7", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nacad", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091020-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091020-7", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000012347", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000012347", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100534969", "url": "https://www.ncbi.nlm.nih.gov/gene/100534969", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002715", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002715", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016641", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016641", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044034", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044034", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100534969", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100534969", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SVPDDKH", "url": "https://omabrowser.org/oma/group/SVPDDKH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AI56", "url": "https://www.orthodb.org/?gene=A0A8M3AI56", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7EZQ7", "url": "https://www.orthodb.org/?gene=E7EZQ7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21713", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21713", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01849", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01849", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19026", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19026", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E7EZQ7", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E7EZQ7", "database": "PRO", "categories": [ "Protein" ] }, { "id": "XP_003200246", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200246", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3AI56", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AI56", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AI56-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AI56-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZQ7", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZQ7-1", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091020-7", "url": "https://zfin.org/ZDB-GENE-091020-7", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPGENAHRSGPTQSLLDSGDSHSELPGPDLSGQTSSSSASTPTDSASSPSASSPPKLSPLCTPFGPRLVMAKPTTSPRPQPEGASFEFEGHFGTMGRPIGRFGRGACRRGPMKMERIKVLTGSEIESDFQEPETMDSRVVMGQEALLRNMETQSGMLQEKQRGQEKSSSVNQPTETSKKSTIGLDEKAKLDTGQVCPIVDQGKSVTSEPEQEKALGQILECQVLESKVRDAESTDSSTLFPENEEEPLSLSQGEVPSLSFSEPPYIVDPQRIGVLPGLDPDRYYTAPSTPIKMAYCSHLKQPWRPGSPSQCPGSPTDESDLCSPPTSPSGSYITAEGGSWTSYTSSTSHSCSPNLTAEAELQDAPACYVGSLSEIGDDLGDEFTTNYKDACLGKPELPELLENAACKVNILTRDACRPHWVTEHVSTQERSSKKDRDCQQDTEISEGSPRARTPDATQAINDPYHSLEMDFNACFSEPSVSLDPALTLEDNAASALDAESKTPVTHSPETIDSNSSYLEIGSSFPLFHGYSRDDGPESDAMIPASMLPFHGSLIFQADSMDITLFPTDDEQGNDVDAYAAGEEEADVDEYDDEYDEDECDGEDVDNDNNAEQQEAANRGERGVEDQNEDDTSASFLNSLSENSINEGVDESFAYQDDTEESIDSTSYNGDEDDHLYSTEKHAELSQKFPGPDEPDQSVSHAKPESSGSESEMEISSGSSELPHAELHEDMAESNVRDESKIIQLSETKPLKGEISRELTAQIKTKDEEGKESRDPSTSEKAQPAPTDNPTSAVSQDKLKQNETTMDSSLEGATAADTSYKTNADGCQQLDQKLGNSMELTYISLQPTETATNDLNKGVPQLTYLDECSPTNIPVCAYPELCDMADNLSSADVLQFERPMNQDNLTENQPANDDVNHGSQNMSCSTYSRLVISPKKENSESSLTERHLYSDSWTPRDPLSLSECCDFEAENLLMCEIARSVHSKGLSVAHNIAAGEDIMGDDEDNNRYCDLPEKMADIDVGVVESNIASWRSIQDLSEAGGGEDDANNLQNPESNALIHCSSEKSLVSSWNDPEKTCTPLIPSELALNMLSNDGKDVKDQTPNADFNIPEDLSTDKLRKESTEVDSDQSRDLETCGTLTSIISPECTGLCGSSKNVISKPSDYLAPIQSLSNSQQITPPDSISENKLAFNLQGGSFGTFTFRKKPTDIKIVATSEATIVQHTSVSHKETSNSNDVVGEKVIQLIPNIKNETASGEAKSTERKLLDQATTGLPNQEKDKVEQHKKGKRETKARQKKGVQDFKENVLYLEQNKMPDGDSHKSGLSQAECNEATPKTARNANLGHDTKPKVIDALKTNTAVSDSMENEKTQCQKKKMKTTSNQTPSFDIFSVKEEIGKTPQNKDVSLAERTEPVQKPEQSIFYSPDSSCIDLKESLHTEPVVATQTADVTKTDEQKELPDSSLSRASLTESTRDINDNHVGASSSLRVDSSKQDRVSPKCLSTVVQEEDLSTPIQESQPIQDISQTSAGFSRIQPPSNKLSQPVSQSSLKTTAISSMDLAAWESEESTMTQFPIQDTCNHESERTAMTAIPCRHENFAVCMGHRTEQSQSTTSIGQTDNTCVQRTMKRLDERETLPCIRPRPDSLVKTQQKQAERQSIERDMCPITYRSKDPDDMDLPFKNNIGSGNETDSDGSVPELEEPSGTMLRPSNPPLSPSPVDESVSRAKQSRSEKKARKAMSKLGLKQIHGVTRITIRKSKNILFVITRPDVFKSPASDIYIVFGEAKIEDLSQQVHKAAAEKFKVPLDPSPLPSDITPSLTIKEESEEEEELDEGGLEQRDIELVMAQANVSRAKAVRALRHNKNDIVNAIMELTM", "length": 1870, "header": "tr|E7EZQ7-1|E7EZQ7_DANRE Isoform 1 of Uncharacterized protein nacad isoform X1 OS=Danio rerio OX=7955 GN=nacad PE=4 SV=1 CANONICAL=E7EZQ7-1" }, "isoforms": [ { "isoform_ac": "A0A8M3AI56-1", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7/entry#A0A8M3AI56-1", "sequence": { "sequence": "MPGENAHRSGPTQSLLDSGDSHSELPGPDLSGQTSSSSASTPTDSASSPSASSPPKLSPLCTPFGPRLVMAKPTTSPRPQPEGASFEFEGHFGTMGRPIGRFGRGACRRGPMKMERIKVLTGSEIESDFQEPETMDSRVVMGQEALLRNMETQSGMLQEKQRGQEKSSSVNQPTETSKKSTIGLDEKAKLDTGQVCPIVDQGKSVTSEPEQEKALGQILECQVLESKVRDAESTDSSTLFPENEEEPLSLSQGEVPSLSFSEPPYIVDPQRIGVLPGLDPDRYYTAPSTPIKMAYCSHLKQPWRPGSPSQCPGSPTDESDLCSPPTSPSGSYITAEGGSWTSYTSSTSHSCSPNLTAEAELQDAPACYVGSLSEIGDDLGDEFTTNYKDACLGKPELPELLENAACKVNILTRDACRPHWVTEHVSTQERSSKKDRDCQQDTEISEGSPRARTPDATQAINDPYHSLEMDFNACFSEPSVSLDPALTLEDNAASALDAESKTPVTHSPETIDSNSSYLEIGSSFPLFHGYSRDDGPESDAMIPASMLPFHGSLIFQADSMDITLFPTDDEQGNDVDAYAAGEEEADVDEYDDEYDEDECDGEDVDNDNNAEQQEAANRGERGVEDQNEDDTSASFLNSLSENSINEGVDESFAYQDDTEESIDSTSYNGDEDDHLYSTEKHAELSQKFPGPDEPDQSVSHAKPESSGSESEMEISSGSSELPHAELHEDMAESNVRDESKIIQLSETKPLKGEISRELTAQIKTKDEEGKESRDPSTSEKAQPAPTDNPTSAVSQDKLKQNETTMDSSLEGATAADTSYKTNADGCQQLDQKLGNSMELTYISLQPTETATNDLNKGVPQLTYLDECSPTNIPVCAYPELCDMADNLSSADVLQFERPMNQDNLTENQPANDDVNHGSQNMSCSTYSRLVISPKKENSESSLTERHLYSDSWTPRDPLSLSECCDFEAENLLMCEIARSVHSKGLSVAHNIAAGEDIMGDDEDNNRYCDLPEKMADIDVGVVESNIASWRSIQDLSEAGGGEDDANNLQNPESNALIHCSSEKSLVSSWNDPEKTCTPLIPSELALNMLSNDGKDVKDQTPNADFNIPEDLSTDKLRKESTEVDSDQSRDLETCGTLTSIISPECTGLCGSSKNVISKPSDYLAPIQSLSNSQQITPPDSISENKLAFNLQGGSFGTFTFRKKPTDIKIVATSEATIVQHTSVSHKETSNSNDVVGEKVIQLIPNIKNETASGEAKSTERKLLDQATTGLPNQEKDKVEQHKKGKRETKARQKKGVQDFKENVLYLEQNKMPDGDSHKSGLSQAECNEATPKTARNANLGHDTKPKVIDALKTNTAVSDSMENEKTQCQKKKMKTTSNQTPSFDIFSVKEEIGKTPQNKDVSLAERTEPVQKPEQSIFYSPDSSCIDLKESLHTEPVVATQTADVTKTDEQKELPDSSLSRASLTESTRDINDNHVGASSSLRVDSSKQDRVSPKCLSTVVQEEDLSTPIQESQPIQDISQTSAGFSRIQPPSNKLSQPVSQSSLKTTAISSMDLAAWESEESTMTQFPIQDTCNHESERTAMTAIPCRHENFAVCMGHRTEQSQSTTSIGQTDNTCVQRTMKRLDERETLPCIRPRPDSLVKTQQKQAERQSIERDMCPITYRSKDPDDMDLPFKNNSSGNETDSDGSVPELEEPSGTMLRPSNPPLSPSPVDESVSRAKQSRSEKKARKAMSKLGLKQIHGVTRITIRKSKNILFVITRPDVFKSPASDIYIVFGEAKIEDLSQQVHKAAAEKFKVPLDPSPLPSDITPSLTIKEESEEEEELDEGGLEQRDIELVMAQANVSRAKAVRALRHNKNDIVNAIMELTM", "length": 1869, "header": "tr|A0A8M3AI56-1|E7EZQ7_DANRE Computationally mapped isoform of Uncharacterized protein nacad isoform X1 OS=Danio rerio OX=7955 GN=nacad PE=4 SV=1 CANONICAL=E7EZQ7-1" }, "locus": {} }, { "isoform_ac": "E7EZQ7-1", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7/entry#E7EZQ7-1", "sequence": { "sequence": "MPGENAHRSGPTQSLLDSGDSHSELPGPDLSGQTSSSSASTPTDSASSPSASSPPKLSPLCTPFGPRLVMAKPTTSPRPQPEGASFEFEGHFGTMGRPIGRFGRGACRRGPMKMERIKVLTGSEIESDFQEPETMDSRVVMGQEALLRNMETQSGMLQEKQRGQEKSSSVNQPTETSKKSTIGLDEKAKLDTGQVCPIVDQGKSVTSEPEQEKALGQILECQVLESKVRDAESTDSSTLFPENEEEPLSLSQGEVPSLSFSEPPYIVDPQRIGVLPGLDPDRYYTAPSTPIKMAYCSHLKQPWRPGSPSQCPGSPTDESDLCSPPTSPSGSYITAEGGSWTSYTSSTSHSCSPNLTAEAELQDAPACYVGSLSEIGDDLGDEFTTNYKDACLGKPELPELLENAACKVNILTRDACRPHWVTEHVSTQERSSKKDRDCQQDTEISEGSPRARTPDATQAINDPYHSLEMDFNACFSEPSVSLDPALTLEDNAASALDAESKTPVTHSPETIDSNSSYLEIGSSFPLFHGYSRDDGPESDAMIPASMLPFHGSLIFQADSMDITLFPTDDEQGNDVDAYAAGEEEADVDEYDDEYDEDECDGEDVDNDNNAEQQEAANRGERGVEDQNEDDTSASFLNSLSENSINEGVDESFAYQDDTEESIDSTSYNGDEDDHLYSTEKHAELSQKFPGPDEPDQSVSHAKPESSGSESEMEISSGSSELPHAELHEDMAESNVRDESKIIQLSETKPLKGEISRELTAQIKTKDEEGKESRDPSTSEKAQPAPTDNPTSAVSQDKLKQNETTMDSSLEGATAADTSYKTNADGCQQLDQKLGNSMELTYISLQPTETATNDLNKGVPQLTYLDECSPTNIPVCAYPELCDMADNLSSADVLQFERPMNQDNLTENQPANDDVNHGSQNMSCSTYSRLVISPKKENSESSLTERHLYSDSWTPRDPLSLSECCDFEAENLLMCEIARSVHSKGLSVAHNIAAGEDIMGDDEDNNRYCDLPEKMADIDVGVVESNIASWRSIQDLSEAGGGEDDANNLQNPESNALIHCSSEKSLVSSWNDPEKTCTPLIPSELALNMLSNDGKDVKDQTPNADFNIPEDLSTDKLRKESTEVDSDQSRDLETCGTLTSIISPECTGLCGSSKNVISKPSDYLAPIQSLSNSQQITPPDSISENKLAFNLQGGSFGTFTFRKKPTDIKIVATSEATIVQHTSVSHKETSNSNDVVGEKVIQLIPNIKNETASGEAKSTERKLLDQATTGLPNQEKDKVEQHKKGKRETKARQKKGVQDFKENVLYLEQNKMPDGDSHKSGLSQAECNEATPKTARNANLGHDTKPKVIDALKTNTAVSDSMENEKTQCQKKKMKTTSNQTPSFDIFSVKEEIGKTPQNKDVSLAERTEPVQKPEQSIFYSPDSSCIDLKESLHTEPVVATQTADVTKTDEQKELPDSSLSRASLTESTRDINDNHVGASSSLRVDSSKQDRVSPKCLSTVVQEEDLSTPIQESQPIQDISQTSAGFSRIQPPSNKLSQPVSQSSLKTTAISSMDLAAWESEESTMTQFPIQDTCNHESERTAMTAIPCRHENFAVCMGHRTEQSQSTTSIGQTDNTCVQRTMKRLDERETLPCIRPRPDSLVKTQQKQAERQSIERDMCPITYRSKDPDDMDLPFKNNIGSGNETDSDGSVPELEEPSGTMLRPSNPPLSPSPVDESVSRAKQSRSEKKARKAMSKLGLKQIHGVTRITIRKSKNILFVITRPDVFKSPASDIYIVFGEAKIEDLSQQVHKAAAEKFKVPLDPSPLPSDITPSLTIKEESEEEEELDEGGLEQRDIELVMAQANVSRAKAVRALRHNKNDIVNAIMELTM", "length": 1870, "header": "tr|E7EZQ7-1|E7EZQ7_DANRE Isoform 1 of Uncharacterized protein nacad isoform X1 OS=Danio rerio OX=7955 GN=nacad PE=4 SV=1 CANONICAL=E7EZQ7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1176, "start_aa": "Thr", "end_pos": 1176, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1176", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 12, "start_aa": "Thr", "end_pos": 12, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr12", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100534969", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100534969", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L8A8-1", "protein_name": "NAC alpha domain containing", "gene_name": "Nacad", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRGRRGRAQPNGPRLSSGREAMSRGAVAVLATPSALTDRGTERQGYRQAHVQAMPGEAAGAELPLPEAGGSGSRTDLPCDAAIATILKGDQREPHGLTPGPSPLALTFLSSKPGARPQPEGASWDAGPSGAASTWVDPAEGSPSLVVLPEGLPLRPVPADVPLPTTLEPRIVMGEETCQVLPSPRAAWPVLRDREGGHTALHPPPELCSQGDPPVPSPPPDLDSYFTPPSTPTKTTYALLPDHGPHRGAWGLEAELLDELLDSTPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSEWGLSPSGSVVDELEPHPTAPPEPPSSESSLSADCSSSWSQEGHFFDPNCLANDPMIPAALLPFRGSLIFQVEAVEVTPLPQEEEEDEEEGAAAAAAAAATPDGDLAGEGEDDSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAASSDSDSASYAGADDDRLYSGEPHAQPSAQNIEQEYRSRTAFPGAAEFTPQTSEQEICLTDSQESAAEIAEEILTLGIESEATRTPPDRQTAPDPQVEEATTVTPWVENKDDSVAEQASKALPEPCQKGTSMILGCKPLTAKAIPDLQEGAGPAMCPVLPENLKEGGQGLPSTMEYVAVASVGPWKAEGGVAIPQDPFMTLPPLLQNTDPTSGPESVAVVMLEPQQDEGCVTVLQDVPVVSLPSPQSTDPTPGPEAGAMATFEFQQAKEGVPELQDTPVASSPALQASDPTSEPEPEAVLTLRSQQDEEIVTVPQESPTASSVPLQSSDPTSEPEPEAVLTLRSQQDEEIVTVPQESPTASSVPLQSSDPTSEPEPEAVLTLRSQQDEEIVTVPQESPTASSVPLQSSDPTSEPEPEAVLTLRSQQDEEIVTVPQESPTVSSVPLQSSDPTSEPEPEVAATLRSQQDEEIVTVPQESPTASSVPLQSSDPTSEPEPEAVLTLRSQQDKEIVTVPQESPTASSVPLQSSDPTSEPEPEVAATPEPQQPEEGVTIPQVAPVALPSPLQGLDSTSDLESVVAGTMESWQDEGIATATQDMPVVAPPPLGGIESTSDPELSAQDTPQALQREAGYTPGTKPSVSEAHQELGVALGPRPVPKEQDAKPPHSELPASDQAQQNGSEPVVKNDNLGVPGEGSGPTLSTKTSEPLSCMGEKVTENLAAPKPGACLEAHDGAKTHSPQRQASRAKNKCGRGPKPPGQGKGSKSTASQGTTETFKAHSAARSETSQPQLMNSAGEGTSLSVKDSSGPRLPVAVSVQSKLGSCPGSPARATCTLSRVYSEETARCAPPFQHPEPVLGLGSGEQPKVTLGTLNLSSENSAGDLLTTPQNRLLDPDPDPSAPSALNRAFQSSPGPPDPCLCPTSQKDPVEEEKPSASHGLRSRAGVQGAAAITTSGSTKPLGARQRVSLSPHSANPKVTPTDAKDPACIISSPCQVPPPSGTQNPSGPRGFPAHEQEDEDSLEEDSQRAPGSGQHSESHGESSGELDEQDISPQKSQCPAQDPAGSNEETTAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSESSALVPELAPGPRVRPECEEQEEEEEEVEEAGLEPRDIELVMAQANVSRAKAVRALKDNHSDIVNAIMELTM", "length": 1670 }, "evidence": [ { "id": "HGNC:22196", "url": "https://alliancegenome.org/gene/HGNC:22196#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O15069-1", "protein_name": "NAC-alpha domain-containing protein 1", "gene_name": "NACAD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGEAARAELLLPEADRPGPRTDLSCDAAAATTILGGDRREPCALTPGPSHLALTFLPSKPGARPQPEGASWDAGPGGAPSAWADPGEGGPSPMLLPEGLSSQALSTEAPLPATLEPRIVMGEETCQALLSPRAARTALRDQEGGHASPDPPPELCSQGDLSVPSPPPDPDSFFTPPSTPTKTTYALLPACGPHGDARDSEAELRDELLDSPPASPSGSYITADGDSWASSPSCSLSLLAPAEGLDFPSGWGLSPQGSMVDERELHPAGTPEPPSSESSLSADSSSSWGQEGHFFDLDFLANDPMIPAALLPFQGSLIFQVEAVEVTPLSPEEEEEEAVADPDPGGDLAGEGEEDSTSASFLQSLSDLSITEGMDEAFAFRDDTSAASSDSDSASYAEADDERLYSGEPHAQATLLQDSVQKTEEESGGGAKGLQAQDGTVSWAVEAAPQTSDRGAYLSQRQELISEVTEEGLALGQESTATVTPHTLQVAPGLQVEVATRVTPQAGEEETDSTAGQESAAMAMPQPSQEGISEILGQESVTAEKLPTPQEETSLTLCPDSPQNLKEEGGLDLPSGRKPVAAATIVPRQAKEDLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSVMTPPLPLQDTELSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATLVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATIVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTPPLPLQDTDLSSAPKPVAAATPVSQQAEEGLTLPQDSAMTAPLPLQDTGPTSGPEPLAVATPQTLQAEAGCAPGTEPVATMAQQEVGEALGPRPAPEEKNAALPTVPEPAALDQVQQDDPQPAAEAGTPWAAQEDADSTLGMEALSLPEPASGAGEEIAEALSRPGREACLEARAHTGDGAKPDSPQKETLEVENQQEGGLKPLAQEHGPRSALGGAREVPDAPPAACPEVSQARLLSPAREERGLSGKSTPEPTLPSAVATEASLDSCPESSVGAVSSLDRGCPDAPAPTSAPTSQQPEPVLGLGSVEQPHEVPSVLGTPLLQPPENLAKGQPSTPVDRPLGPDPSAPGTLAGAALPPLEPPAPCLCQDPQEDSVEDEEPPGSLGLPPPQAGVQPAAAAVSGTTQPLGTGPRVSLSPHSPLLSPKVASMDAKDLALQILPPCQVPPPSGPQSPAGPQGLSAPEQQEDEDSLEEDSPRALGSGQHSDSHGESSAELDEQDILAPQTVQCPAQAPAGGSEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPESAPRPRVRLECKEEEEEEEEEVDEAGLELRDIELVMAQANVSRAKAVRALRDNHSDIVNAIMELTM", "length": 1562 }, "evidence": [ { "id": "HGNC:22196", "url": "https://alliancegenome.org/gene/HGNC:22196#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091020-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091020-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P38879-1", "protein_name": "Nascent polypeptide-associated complex subunit alpha", "gene_name": "EGD2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSAIPENANVTVLNKNEKKARELIGKLGLKQIPGIIRVTFRKKDNQIYAIEKPEVFRSAGGNYVVFGEAKVDNFTQKLAAAQQQAQASGIMPSNEDVATKSPEDIQADMQAAAEGSVNAAAEEDDEEGEVDAGDLNKDDIELVVQQTNVSKNQAIKALKAHNGDLVNAIMSLSK", "length": 174 }, "evidence": [ { "id": "HGNC:22196", "url": "https://alliancegenome.org/gene/HGNC:22196#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5SWP3-1", "protein_name": "NAC-alpha domain-containing protein 1", "gene_name": "Nacad", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSALPLALRSARRAGARSLGLIGGRGSADVIYAPPPPSRGAVAVLATPSALTDRGTERQGYRQAHVQAMPGEAAGAELPLPEAGGPGSRTDHSCDAAIATILKGDQLEPHGLTPGPSPLALTFLSSKPGARPQPEGASWDAGPSGAASAWVDPAEGSPSLVVLPEGLPLRPVPAEGPLPTTLEPRIVMGEETCQVIASPRAAWPVLRDREGGHPALHPPPELCSQGDPPVPSPPPDLESYFTPPSTPTKSTHALLPDHGPHRDAWDLEAELLDELLDSTPASPSGSYITADGDSWASSPSCSLSLLDPAEGLDFPSDWGLSPSGSVADDLEPHPAAPPEPPSSESSLSADSSSSWSQEGHFFDPNFLANDPMIPAALLPFRGSLIFQVEAVEVTPLPQEEEEDEEDVAATAAAAAPAAATPDGDLAGEGEDDSTSASFLQSLSDLSIIEGMDEAFAFRDDTSAASSDSDSASYAGADDDRLYSGEPHAQPSAQNTEQAYRSRATFPGIESTPQTSEQEICLTNSQESVAEIAEEILTLGLESEAMRTPPDQQAAPGPQVEETPTVTPWVGNKVDLVVEQVSKALPEPCQEGISTTLGCKPLTAEAIPDLQEGASPSLCPVLPEKKEEGQGLPSTLEYVAVALEGPWKAEGGVTIPQDPLMTLPPLLQSTVPTSGPESVAVVALEPQQNEGCVTVLPDVPVVLPPSPQSVDPSSGPEAMAVATYEFQRAKEGTPGLQDSPVAASPALQGPDPTSEPEPEVVVTSRSQQDEGIVTVPQESPTASSLTLQSSHPTSDQEREVAATLGPQQAEEGVTIPQVAPVASPSLLQGLESTSDLESVVVGTPESQQDEGIATATQDTPVMAPPPLRGTDSTSDPELIAPDTSQALQREAGHTPGTKPSVSEAHQELGVASGPRPVPKEGDAEPPPHSAPPASNQAQQNGSEPGYKSDSFGAPEESDSTLSTKTSEPTSCMGEKVAANMSAPKQGACLEAHDGVKTHSPQREALRSKNKRGRGTKSPGQGNGPKSATSQGAVETCRAHSAARSEVSQPQLRSNEDTSGPRLPVAVSVQARLGSCPGSPARATCTLSRVYAEETSRCAPPFQHLEPMLGLGSAEQPKVTPGILNLSPDNSAGDLLTTSQNRFLDPDPAPSTLDRASQSSPGPPDPCLCPPPQKASEEEEKPPASRGPMPRAGAQGAAAITTSGSTKPPGARQRVSLSPHSTLNPKVAPTDTKDLACIISSPCQVPPPSGTQNPSGPREFPALEQKDEDSLEEDAQRAPGSGQRWESHGESSSELDEYLAPPPDAQRTPGSGQRSESHGESSSELGEQDLSPQKSQCPAQGPAGSNEETIAKAKQSRSEKKARKAMSKLGLRQIQGVTRITIQKSKNILFVIAKPDVFKSPASDTYVVFGEAKIEDLSQQVHKAAAEKFKVPSEPSALVPELSPGPRVRPECEEQEEEDEEVEEAGLEPRDIELVMAQANVTRAKAVRALKDNHSDIVNAIMELTM", "length": 1504 }, "evidence": [ { "id": "HGNC:22196", "url": "https://alliancegenome.org/gene/HGNC:22196#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q94518-1", "protein_name": "Nascent polypeptide-associated complex subunit alpha", "gene_name": "Nacalpha", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPELTEIKSEAAPSTSAEAKPEDVRVEDDGSDSDSDGGMPGLEEAVAATTQLGGGATGLPIDLVSKAKQSRGEKKARKIMLKLGLKQIQGVNRVTIRKSKNILFVINNPDVYKNPHSDTYIVFGEAKIEDLSQQAQVAAAEKFKAPEAAGAADSVGATTSVAPIAEEDEEDVDDTGVDEKDIELVITQANTTRAKAIKALKNNNNDIVNAIMELTML", "length": 217 }, "evidence": [ { "id": "HGNC:22196", "url": "https://alliancegenome.org/gene/HGNC:22196#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nascent polypeptide-associated complex", "id": "GO:0005854", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005854", "evidence": [ { "database": "UniProtKB", "id": "E7EZQ7", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7EZQ7", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "unfolded protein binding", "id": "GO:0051082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051082", "evidence": [ { "database": "UniProtKB", "id": "E7EZQ7", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "protein targeting to membrane", "id": "GO:0006612", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006612", "evidence": [ { "database": "UniProtKB", "id": "E7EZQ7", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1248, "end_pos": 1250, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1378, "end_pos": 1380, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1683, "end_pos": 1685, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1844, "end_pos": 1846, "annotation": "n_glycosylation_sequon" }, { "start_pos": 354, "end_pos": 356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 801, "end_pos": 803, "annotation": "n_glycosylation_sequon" }, { "start_pos": 886, "end_pos": 888, "annotation": "n_glycosylation_sequon" }, { "start_pos": 903, "end_pos": 905, "annotation": "n_glycosylation_sequon" }, { "start_pos": 920, "end_pos": 922, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EZQ7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZQ7" }, { "id": "PS51151", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51151" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NAC-A/B", "eco_id": "ECO_0000259", "start_pos": 1724, "end_pos": 1789, "start_aa": "Ser", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 12, 1176 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1248, "end_pos": 1250 }, { "start_pos": 1378, "end_pos": 1380 }, { "start_pos": 1683, "end_pos": 1685 }, { "start_pos": 1844, "end_pos": 1846 }, { "start_pos": 354, "end_pos": 356 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 801, "end_pos": 803 }, { "start_pos": 886, "end_pos": 888 }, { "start_pos": 903, "end_pos": 905 }, { "start_pos": 920, "end_pos": 922 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FA89-1", "uniprot_ac": "E7FA89", "uniprot_id": "E7FA89_DANRE", "mass": { "chemical_mass": 161487.0, "monoisotopic_mass": 161487.0 }, "refseq": { "ac": "XP_689392", "name": "zinc finger MYM-type protein 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689392" }, "gene_names": [ { "name": "si:ch211-266o15.1", "type": "recommended", "evidence": [ { "id": "E7FA89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FA89" } ] }, { "name": "si:ch211-266o15.1", "type": "synonym", "evidence": [ { "id": "XP_689392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689392" } ] } ], "protein_names": [ { "name": "Zinc finger MYM-type protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "E7FA89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FA89/entry#names_and_taxonomy" } ] }, { "name": "zinc finger MYM-type protein 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_689392", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689392" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_689392.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_689392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689392" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FA89", "url": "https://www.uniprot.org/uniprotkb/E7FA89" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-266o15.1", "url": "https://www.uniprot.org/uniprotkb/E7FA89", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131127-116", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-116", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000057681", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000057681", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "560900", "url": "https://www.ncbi.nlm.nih.gov/gene/560900", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010507", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010507", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021893", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021893", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051284", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051284", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057926", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057926", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:560900", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560900", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DKWADKR", "url": "https://omabrowser.org/oma/group/DKWADKR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AIS7", "url": "https://www.orthodb.org/?gene=A0A8M3AIS7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FA89", "url": "https://www.orthodb.org/?gene=E7FA89", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "X1WH87", "url": "https://www.orthodb.org/?gene=X1WH87", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45736", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45736", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45736:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45736:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06467", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06467", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12012", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12012", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24900", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24900", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25561", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25561", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_689392", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689392", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3AIS7", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AIS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AIS7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AIS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQT7", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQT7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQU3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQU3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQU5", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQU5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQV8", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQV8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQV8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQV8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQX4", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQX4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FA89", "url": "https://www.uniprot.org/uniprotkb/E7FA89", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FA89-1", "url": "https://www.uniprot.org/uniprotkb/E7FA89-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X1WH87", "url": "https://www.uniprot.org/uniprotkb/X1WH87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "X1WH87-1", "url": "https://www.uniprot.org/uniprotkb/X1WH87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131127-116", "url": "https://zfin.org/ZDB-GENE-131127-116", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDQPSELEVKSSGDQGESSSGQLGDEELDGLPVFGTDEDDWEVDSSFAQKAFSQTDGNSNDKNDAAATEENSSSANEEMDVETEREKVSEDTRVTPSSVIDLQEEIQSELRIESSRSDAIPEPHLETTDRDTSYSPVIRIKDEPIDEDYDKALMPESDLSRIKQELDGSDNNETEASSASDELRISSVYSVSGNSSDAVSASVAPSQQSSFSVISQSAASLRGTTILLPAQAQTPLQLQLQHKAQMHSQIQAQARMQPPMMAQAQLQAVPPQPPQIHAPPPTVRICCSGCSKVLQKGQTAFQRKGSNQLFCSTVCLTSFSLPSVQFTPIIAPKKTCHLCLKVIVNLKDLITIPVGSMNTLKEFCSQACLSIYRDRYEDAPPDLFTHCNVCKLVKEIQHEVTHLGAVHKLCSDECFARFRSSRNLYMSYCENCGNCKASGNYHLVQIDDSIKKFCCVECIANYKQKSGKRLHCPYCQDIRNIDQMMEGTNIQGVTEFFCSQRCVALSQASPSLTGTAFPCTSCKKVVIPQYHLAISDGSIRNFCSLDCVGKFQEKLNSPVPHNQMNGTSHTPQPQSAVPPPPRPTADHLQPIQNSSSTSHNPPPPPPPLPPPPPFVPPSNPNPVPTYVPAPGVMNSQDTQQQQQWPSKPPSSSDPMRLTCRQCQNHFSSKPEVFQFKGHAGLFCSRACCDTYKKEGNVKALCEYCKLEKVVKDIITYEKQPRSFCCEGCKLLFKHELAKRHGGQCRVCAYCQNMTHKTIQNFFGGKLEEFCTEECMSLYTVLFYEMAKCSGCKNQGSLKESLVWDGVTRHFCNLSCLLQFCSKCITPHQPLSNGTVSNTTTVQAPLSLSKDMPVIGGVVSLASTLPGNTALTGALPTSNASSKNIGEASTQTDAAVGAIPHRRMLKNKALMCRPITEEQGVQCQPEPPVPPNMSEKVINENGEIVRYVPVPVPIPMPVYIPVPMHLYTQYTPFPMGFPLPVPVPMVIPGPQDAPEQKDTKCSLPAQSSVEDDEPEKGKDKPASHDQGSTYSGDLESEAQSTPLSWAETEDAGASVKPAVPATEAEEPSAEAEDHTPPTTNLTKEQPDLENDFPLTTADPGSAKENRLVLTLKRRKRGRDGHPPRKRGRKRSGTDTSSSVWLSTSSSKLNQTYGVEAWASWVRMKRGHAEQEQQAPEPMTMKEDVLQCSSADLSYGLCRFIKEVRRPNGEEYQPDSIYYLCLGIQQCLLENERLENIFTDPLYNQFITDITTLLKDWVNKVSPGGYMHSRVEEEYLWECKQLGALSPIVLLNTLLFFGSKLLNLKTVEEHRRLAFSNVSHCSKTTKSGLTSYLRFRLPNKEEEKEKKSPAGKRKRDEESVEEEFLEMPENVENPLRCPVRLYEFYLSKCSNSVKQRPDLFYLQPEASCHPSSPVWYSAQPLDSTMMESMLTRILAIQDIHLDSKHQQKYLDSSDEESS", "length": 1456, "header": "tr|E7FA89-1|E7FA89_DANRE Isoform 1 of Zinc finger MYM-type protein 4 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-266o15.1 PE=1 SV=1 CANONICAL=E7FA89-1" }, "isoforms": [ { "isoform_ac": "A0A8M3AIS7-1", "url": "https://www.uniprot.org/uniprotkb/E7FA89/entry#A0A8M3AIS7-1", "sequence": { "sequence": "MDQPSELEVKSSGDQGESSSGQLGDEELDGLPVFGTDEDDWEVDSSFAQKAFSQTDGNSNDKNDAAATEENSSSANEEMDVETEREKVSEDTRVTPSSVIDLQEEIQSELRIESSRSDAIPEPHLETTDRDTSYSPVIRIKDEPIDEDYDKALMPESDLSRIKQELDGSDNNETEASSASDELRISSVYSVSGNSSDAVSASVAPSQQSSFSVISQSAASLRGTTILLPAQAQTPLQLQLQHKAQMHSQIQAQARMQPPMMAQAQLQAVPPQPPQIHAPPPTVRICCSGCSKVLQKGQTAFQRKGSNQLFCSTVCLTSFSLPSVQFTPIIAPKKTCHLCLKVIVNLKDLITIPVGSMNTLKEFCSQACLSIYRDRYEDAPPDLFTHCNVCKLVKEIQHEVTHLGAVHKLCSDECFARFRSSRNLYMSYCENCGNCKASGNYHLVQIDDSIKKFCCVECIANYKQSGKRLHCPYCQDIRNIDQMMEGTNIQGVTEFFCSQRCVALSQASPSLTGTAFPCTSCKKVVIPQYHLAISDGSIRNFCSLDCVGKFQEKLNSPVPHNQMNGTSHTPQPQSAVPPPPRPTADHLQPIQNSSSTSHNPPPPPPPLPPPPPFVPPSNPNPVPTYVPAPGVMNSQDTQQQQQWPSKPPSSSDPMRLTCRQCQNHFSSKPEVFQFKGHAGLFCSRACCDTYKKEGNVKALCEYCKLEKVVKDIITYEKQPRSFCCEGCKLLFKHELAKRHGGQCRVCAYCQNMTHKTIQNFFGGKLEEFCTEECMSLYTVLFYEMAKCSGCKNQGSLKESLVWDGVTRHFCNLSCLLQFCSKCITPHQPLSNGTVSNTTTVQAPLSLSKDMPVIGGVVSLASTLPGNTALTGALPTSNASSKNIGEASTQTDAAVGAIPHRRMLKNKALMCRPITEEQGVQCQPEPPVPPNMSEKVINENGEIVRYVPVPVPIPMPVYIPVPMHLYTQYTPFPMGFPLPVPVPMVIPGPQDAPEQKDTKCSLPAQSSVEDDEPEKGKDKPASHDQGSTYSGDLESEAQSTPLSWAETEDAGASVKPAVPATEAEEPSAEAEDHTPPTTNLTKEQPDLENDFPLTTADPGSAKENRLVLTLKRRKRGRDGHPPRKRGRKRSGTDTSSSVWLSTSSSKLNQTYGVEAWASWVRMKRGHAEQEQQAPEPMTMKEDVLQCSSADLSYGLCRFIKEVRRPNGEEYQPDSIYYLCLGIQQCLLENERLENIFTDPLYNQFITDITTLLKDWVNKVSPGGYMHSRVEEEYLWECKQLGALSPIVLLNTLLFFGSKLLNLKTVEEHRRLAFSNVSHCSKTTKSGLTSYLRFRLPNKEEEKEKKSPAGKRKRDEESVEEEFLEMPENVENPLRCPVRLYEFYLSKCSNSVKQRPDLFYLQPEASCHPSSPVWYSAQPLDSTMMESMLTRILAIQDIHLDSKHQQKYLDSSDEESS", "length": 1455, "header": "tr|A0A8M3AIS7-1|E7FA89_DANRE Computationally mapped isoform of Zinc finger MYM-type protein 4 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-266o15.1 PE=1 SV=1 CANONICAL=E7FA89-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQT7-1", "url": "https://www.uniprot.org/uniprotkb/E7FA89/entry#A0AC58HQT7-1", "sequence": { "sequence": "MDQPSELEVKSSGDQGESSSGQLGDEELDGLPVFGTDEDDWEVDSSFAQKAFSQTDGNSNDKNDAAEENSSSANEEMDVETEREKVSEDTRVTPSSVIDLQEEIQSELRIESSRSDAIPEPHLETTDRDTSYSPVIRIKDEPIDEDYDKALMPESDLSRIKQELDGSDNNETEASSASDELRISSVYSVSGNSSDAVSASVAPSQQSSFSVISQSAASLRGTTILLPAQAQTPLQLQLQHKAQMHSQIQAQARMQPPMMAQAQLQAVPPQPPQIHAPPPTVRICCSGCSKVLQKGQTAFQRKGSNQLFCSTVCLTSFSLPSVQFTPIIAPKKTCHLCLKVIVNLKDLITIPVGSMNTLKEFCSQACLSIYRDRYEDAPPDLFTHCNVCKLVKEIQHEVTHLGAVHKLCSDECFARFRSSRNLYMSYCENCGNCKASGNYHLVQIDDSIKKFCCVECIANYKQSGKRLHCPYCQDIRNIDQMMEGTNIQGVTEFFCSQRCVALSQASPSLTGTAFPCTSCKKVVIPQYHLAISDGSIRNFCSLDCVGKFQEKLNSPVPHNQMNGTSHTPQPQSAVPPPPRPTADHLQPIQNSSSTSHNPPPPPPPLPPPPPFVPPSNPNPVPTYVPAPGVMNSQDTQQQQQWPSKPPSSSDPMRLTCRQCQNHFSSKPEVFQFKGHAGLFCSRACCDTYKKEGNVKALCEYCKLEKVVKDIITYEKQPRSFCCEGCKLLFKHELAKRHGGQCRVCAYCQNMTHKTIQNFFGGKLEEFCTEECMSLYTVLFYEMAKCSGCKNQGSLKESLVWDGVTRHFCNLSCLLQFCSKCITPHQPLSNGTVSNTTTVQAPLSLSKDMPVIGGVVSLASTLPGNTALTGALPTSNASSKNIGEASTQTDAAVGAIPHRRMLKNKALMCRPITEEQGVQCQPEPPVPPNMSEKVINENGEIVRYVPVPVPIPMPVYIPVPMHLYTQYTPFPMGFPLPVPVPMVIPGPQDAPEQKDTKCSLPAQSSVEDDEPEKGKDKPASHDQGSTYSGDLESEAQSTPLSWAETEDAGASVKPAVPATEAEEPSAEAEDHTPPTTNLTKEQPDLENDFPLTTADPGSAKENRLVLTLKRRKRGRDGHPPRKRGRKRSGTDTSSSVWLSTSSSKLNQTYGVEAWASWVRMKRGHAEQEQQAPEPMTMKEDVLQCSSADLSYGLCRFIKEVRRPNGEEYQPDSIYYLCLGIQQCLLENERLENIFTDPLYNQFITDITTLLKDWVNKVSPGGYMHSRVEEEYLWECKQLGALSPIVLLNTLLFFGSKLLNLKTVEEHRRLAFSNVSHCSKTTKSGLTSYLRFRLPNKEEEKEKKSPAGKRKRDEESVEEEFLEMPENVENPLRCPVRLYEFYLSKCSNSVKQRPDLFYLQPEASCHPSSPVWYSAQPLDSTMMESMLTRILAIQDIHLDSKHQQKYLDSSDEESS", "length": 1453, "header": "tr|A0AC58HQT7-1|A0AC58HQT7_DANRE Computationally mapped isoform of Zinc finger MYM-type protein 4 isoform X6 OS=Danio rerio OX=7955 GN=si:ch211-266o15.1 PE=1 SV=1 CANONICAL=E7FA89-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQU3-1", "url": "https://www.uniprot.org/uniprotkb/E7FA89/entry#A0AC58HQU3-1", "sequence": { "sequence": "MDQPSELEVKSSGDQGESSSGQLGDEELDGLPVFGTDEDDWEVDSSFAQKAFSQTDGNSNDKNDAAEENSSSANEEMDVETEREKVSEDTRVTPSSVIDLQEEIQSELRIESSRSDAIPEPHLETTDRDTSYSPVIRIKDEPIDEDYDKALMPESDLSRIKQELDGSDNNETEASSASDELRISSVYSVSGNSSDAVSASVAPSQQSSFSVISQSAASLRGTTILLPAQAQTPLQLQLQHKAQMHSQIQAQARMQPPMMAQAQLQAVPPQPPQIHAPPPTVRICCSGCSKVLQKGQTAFQRKGSNQLFCSTVCLTSFSLPSVQFTPIIAPKKTCHLCLKVIVNLKDLITIPVGSMNTLKEFCSQACLSIYRDRYEDAPPDLFTHCNVCKLVKEIQHEVTHLGAVHKLCSDECFARFRSSRNLYMSYCENCGNCKASGNYHLVQIDDSIKKFCCVECIANYKQSGKRLHCPYCQDIRNIDQMMEGTNIQGVTEFFCSQRCVALSQASPSLTGTAFPCTSCKKVVIPQYHLAISDGSIRNFCSLDCVGKFQEKLNSPVPHNQMNGTSHTPQPQSAVPPPPRPTADHLQPIQNSSSTSHNPPPPPPPLPPPPPFVPPSNPNPVPTYVPAPGVMNSQDTQQQQQWPSKPPSSSDPMRLTCRQCQNHFSSKPEVFQFKGHAGLFCSRACCDTYKKEGNVKALCEYCKLEKVVKDIITYEKQPRSFCCEGCKLLFKHELAKRHGGQCRVCAYCQNMTHKTIQNFFGGKLEEFCTEECMSLYTVLFYEMAKCSGCKNQGSLKESLVWDGVTRHFCNLSCLLQFCSKCITPHQPLSNGTVSNTTTVQAPLSLSKDMPVIGGVVSLASTLPGNTALTGALPTSNASSKNIGEASTQTDAAVGAIPHRRMLKNKALMCRPITEEQGVQCQPEPPVPPNMSEKVINENGEIVRYVPVPVPIPMPVYIPVPMHLYTQYTPFPMGFPLPVPVPMVIPGPQDAPEQKDTKCSLPAQSSVEDDEPEKGKDKPASHDQGSTYSGDLESEAQSTPLSWAETEDAGASVKPAVPATEAEEPSAEAEDHTPPTTNLTKEQPDLENDFPLTTADPGSAKENRLVLTLKRRKRGRDGHPPRKRGRKRSGTDTSSSVWLSTSSSKLNQTYGVEAWASWVRMKRGHAEQEQQAQPMTMKEDVLQCSSADLSYGLCRFIKEVRRPNGEEYQPDSIYYLCLGIQQCLLENERLENIFTDPLYNQFITDITTLLKDWVNKVSPGGYMHSRVEEEYLWECKQLGALSPIVLLNTLLFFGSKLLNLKTVEEHRRLAFSNVSHCSKTTKSGLTSYLRFRLPNKEEEKEKKSPAGKRKRDEESVEEEFLEMPENVENPLRCPVRLYEFYLSKCSNSVKQRPDLFYLQPEASCHPSSPVWYSAQPLDSTMMESMLTRILAIQDIHLDSKHQQKYLDSSDEESS", "length": 1452, "header": "tr|A0AC58HQU3-1|A0AC58HQU3_DANRE Computationally mapped isoform of Zinc finger MYM-type protein 4 isoform X8 OS=Danio rerio OX=7955 GN=si:ch211-266o15.1 PE=1 SV=1 CANONICAL=E7FA89-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQU5-1", "url": "https://www.uniprot.org/uniprotkb/E7FA89/entry#A0AC58HQU5-1", "sequence": { "sequence": "MDQPSELEVKSSGDQGESSSGQLGDEELDGLPVFGTDEDDWEVDSSFAQKAFSQTDGNSNDKNDAAEENSSSANEEMDVETEREKVSEDTRVTPSSVIDLQEEIQSELRIESSRSDAIPEPHLETTDRDTSYSPVIRIKDEPIDEDYDKALMPESDLSRIKQELDGSDNNETEASSASDELRISSVYSVSGNSSDAVSASVAPSQQSSFSVISQSAASLRGTTILLPAQAQTPLQLQLQHKAQMHSQIQAQARMQPPMMAQAQLQAVPPQPPQIHAPPPTVRICCSGCSKVLQKGQTAFQRKGSNQLFCSTVCLTSFSLPSVQFTPIIAPKKTCHLCLKVIVNLKDLITIPVGSMNTLKEFCSQACLSIYRDRYEDAPPDLFTHCNVCKLVKEIQHEVTHLGAVHKLCSDECFARFRSSRNLYMSYCENCGNCKASGNYHLVQIDDSIKKFCCVECIANYKQKSGKRLHCPYCQDIRNIDQMMEGTNIQGVTEFFCSQRCVALSQASPSLTGTAFPCTSCKKVVIPQYHLAISDGSIRNFCSLDCVGKFQEKLNSPVPHNQMNGTSHTPQPQSAVPPPPRPTADHLQPIQNSSSTSHNPPPPPPPLPPPPPFVPPSNPNPVPTYVPAPGVMNSQDTQQQQQWPSKPPSSSDPMRLTCRQCQNHFSSKPEVFQFKGHAGLFCSRACCDTYKKEGNVKALCEYCKLEKVVKDIITYEKQPRSFCCEGCKLLFKHELAKRHGGQCRVCAYCQNMTHKTIQNFFGGKLEEFCTEECMSLYTVLFYEMAKCSGCKNQGSLKESLVWDGVTRHFCNLSCLLQFCSKCITPHQPLSNGTVSNTTTVQAPLSLSKDMPVIGGVVSLASTLPGNTALTGALPTSNASSKNIGEASTQTDAAVGAIPHRRMLKNKALMCRPITEEQGVQCQPEPPVPPNMSEKVINENGEIVRYVPVPVPIPMPVYIPVPMHLYTQYTPFPMGFPLPVPVPMVIPGPQDAPEQKDTKCSLPAQSSVEDDEPEKGKDKPASHDQGSTYSGDLESEAQSTPLSWAETEDAGASVKPAVPATEAEEPSAEAEDHTPPTTNLTKEQPDLENDFPLTTADPGSAKENRLVLTLKRRKRGRDGHPPRKRGRKRSGTDTSSSVWLSTSSSKLNQTYGVEAWASWVRMKRGHAEQEQQAQPMTMKEDVLQCSSADLSYGLCRFIKEVRRPNGEEYQPDSIYYLCLGIQQCLLENERLENIFTDPLYNQFITDITTLLKDWVNKVSPGGYMHSRVEEEYLWECKQLGALSPIVLLNTLLFFGSKLLNLKTVEEHRRLAFSNVSHCSKTTKSGLTSYLRFRLPNKEEEKEKKSPAGKRKRDEESVEEEFLEMPENVENPLRCPVRLYEFYLSKCSNSVKQRPDLFYLQPEASCHPSSPVWYSAQPLDSTMMESMLTRILAIQDIHLDSKHQQKYLDSSDEESS", "length": 1453, "header": "tr|A0AC58HQU5-1|A0AC58HQU5_DANRE Computationally mapped isoform of Zinc finger MYM-type protein 4 isoform X7 OS=Danio rerio OX=7955 GN=si:ch211-266o15.1 PE=1 SV=1 CANONICAL=E7FA89-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQV8-1", "url": "https://www.uniprot.org/uniprotkb/E7FA89/entry#A0AC58HQV8-1", "sequence": { "sequence": "MDQPSELEVKSSGDQGESSSGQLGDEELDGLPVFGTDEDDWEVDSSFAQKAFSQTDGNSNDKNDAAATEENSSSANEEMDVETEREKVSEDTRVTPSSVIDLQEEIQSELRIESSRSDAIPEPHLETTDRDTSYSPVIRIKDEPIDEDYDKALMPESDLSRIKQELDGSDNNETEASSASDELRISSVYSVSGNSSDAVSASVAPSQQSSFSVISQSAASLRGTTILLPAQAQTPLQLQLQHKAQMHSQIQAQARMQPPMMAQAQLQAVPPQPPQIHAPPPTVRICCSGCSKVLQKGQTAFQRKGSNQLFCSTVCLTSFSLPSVQFTPIIAPKKTCHLCLKVIVNLKDLITIPVGSMNTLKEFCSQACLSIYRDRYEDAPPDLFTHCNVCKLVKEIQHEVTHLGAVHKLCSDECFARFRSSRNLYMSYCENCGNCKASGNYHLVQIDDSIKKFCCVECIANYKQSGKRLHCPYCQDIRNIDQMMEGTNIQGVTEFFCSQRCVALSQASPSLTGTAFPCTSCKKVVIPQYHLAISDGSIRNFCSLDCVGKFQEKLNSPVPHNQMNGTSHTPQPQSAVPPPPRPTADHLQPIQNSSSTSHNPPPPPPPLPPPPPFVPPSNPNPVPTYVPAPGVMNSQDTQQQQQWPSKPPSSSDPMRLTCRQCQNHFSSKPEVFQFKGHAGLFCSRACCDTYKKEGNVKALCEYCKLEKVVKDIITYEKQPRSFCCEGCKLLFKHELAKRHGGQCRVCAYCQNMTHKTIQNFFGGKLEEFCTEECMSLYTVLFYEMAKCSGCKNQGSLKESLVWDGVTRHFCNLSCLLQFCSKCITPHQPLSNGTVSNTTTVQAPLSLSKDMPVIGGVVSLASTLPGNTALTGALPTSNASSKNIGEASTQTDAAVGAIPHRRMLKNKALMCRPITEEQGVQCQPEPPVPPNMSEKVINENGEIVRYVPVPVPIPMPVYIPVPMHLYTQYTPFPMGFPLPVPVPMVIPGPQDAPEQKDTKCSLPAQSSVEDDEPEKGKDKPASHDQGSTYSGDLESEAQSTPLSWAETEDAGASVKPAVPATEAEEPSAEAEDHTPPTTNLTKEQPDLENDFPLTTADPGSAKENRLVLTLKRRKRGRDGHPPRKRGRKRSGTDTSSSVWLSTSSSKLNQTYGVEAWASWVRMKRGHAEQEQQAQPMTMKEDVLQCSSADLSYGLCRFIKEVRRPNGEEYQPDSIYYLCLGIQQCLLENERLENIFTDPLYNQFITDITTLLKDWVNKVSPGGYMHSRVEEEYLWECKQLGALSPIVLLNTLLFFGSKLLNLKTVEEHRRLAFSNVSHCSKTTKSGLTSYLRFRLPNKEEEKEKKSPAGKRKRDEESVEEEFLEMPENVENPLRCPVRLYEFYLSKCSNSVKQRPDLFYLQPEASCHPSSPVWYSAQPLDSTMMESMLTRILAIQDIHLDSKHQQKYLDSSDEESS", "length": 1454, "header": "tr|A0AC58HQV8-1|A0AC58HQV8_DANRE Computationally mapped isoform of Zinc finger MYM-type protein 4 isoform X5 OS=Danio rerio OX=7955 GN=si:ch211-266o15.1 PE=1 SV=1 CANONICAL=E7FA89-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQX4-1", "url": "https://www.uniprot.org/uniprotkb/E7FA89/entry#A0AC58HQX4-1", "sequence": { "sequence": "MDQPSELEVKSSGDQGESSSGQLGDEELDGLPVFGTDEDDWEVDSSFAQKAFSQTDGNSNDKNDAAEENSSSANEEMDVETEREKVSEDTRVTPSSVIDLQEEIQSELRIESSRSDAIPEPHLETTDRDTSYSPVIRIKDEPIDEDYDKALMPESDLSRIKQELDGSDNNETEASSASDELRISSVYSVSGNSSDAVSASVAPSQQSSFSVISQSAASLRGTTILLPAQAQTPLQLQLQHKAQMHSQIQAQARMQPPMMAQAQLQAVPPQPPQIHAPPPTVRICCSGCSKVLQKGQTAFQRKGSNQLFCSTVCLTSFSLPSVQFTPIIAPKKTCHLCLKVIVNLKDLITIPVGSMNTLKEFCSQACLSIYRDRYEDAPPDLFTHCNVCKLVKEIQHEVTHLGAVHKLCSDECFARFRSSRNLYMSYCENCGNCKASGNYHLVQIDDSIKKFCCVECIANYKQKSGKRLHCPYCQDIRNIDQMMEGTNIQGVTEFFCSQRCVALSQASPSLTGTAFPCTSCKKVVIPQYHLAISDGSIRNFCSLDCVGKFQEKLNSPVPHNQMNGTSHTPQPQSAVPPPPRPTADHLQPIQNSSSTSHNPPPPPPPLPPPPPFVPPSNPNPVPTYVPAPGVMNSQDTQQQQQWPSKPPSSSDPMRLTCRQCQNHFSSKPEVFQFKGHAGLFCSRACCDTYKKEGNVKALCEYCKLEKVVKDIITYEKQPRSFCCEGCKLLFKHELAKRHGGQCRVCAYCQNMTHKTIQNFFGGKLEEFCTEECMSLYTVLFYEMAKCSGCKNQGSLKESLVWDGVTRHFCNLSCLLQFCSKCITPHQPLSNGTVSNTTTVQAPLSLSKDMPVIGGVVSLASTLPGNTALTGALPTSNASSKNIGEASTQTDAAVGAIPHRRMLKNKALMCRPITEEQGVQCQPEPPVPPNMSEKVINENGEIVRYVPVPVPIPMPVYIPVPMHLYTQYTPFPMGFPLPVPVPMVIPGPQDAPEQKDTKCSLPAQSSVEDDEPEKGKDKPASHDQGSTYSGDLESEAQSTPLSWAETEDAGASVKPAVPATEAEEPSAEAEDHTPPTTNLTKEQPDLENDFPLTTADPGSAKENRLVLTLKRRKRGRDGHPPRKRGRKRSGTDTSSSVWLSTSSSKLNQTYGVEAWASWVRMKRGHAEQEQQAPEPMTMKEDVLQCSSADLSYGLCRFIKEVRRPNGEEYQPDSIYYLCLGIQQCLLENERLENIFTDPLYNQFITDITTLLKDWVNKVSPGGYMHSRVEEEYLWECKQLGALSPIVLLNTLLFFGSKLLNLKTVEEHRRLAFSNVSHCSKTTKSGLTSYLRFRLPNKEEEKEKKSPAGKRKRDEESVEEEFLEMPENVENPLRCPVRLYEFYLSKCSNSVKQRPDLFYLQPEASCHPSSPVWYSAQPLDSTMMESMLTRILAIQDIHLDSKHQQKYLDSSDEESS", "length": 1454, "header": "tr|A0AC58HQX4-1|A0AC58HQX4_DANRE Computationally mapped isoform of Zinc finger MYM-type protein 4 isoform X4 OS=Danio rerio OX=7955 GN=si:ch211-266o15.1 PE=1 SV=1 CANONICAL=E7FA89-1" }, "locus": {} }, { "isoform_ac": "E7FA89-1", "url": "https://www.uniprot.org/uniprotkb/E7FA89/entry#E7FA89-1", "sequence": { "sequence": "MDQPSELEVKSSGDQGESSSGQLGDEELDGLPVFGTDEDDWEVDSSFAQKAFSQTDGNSNDKNDAAATEENSSSANEEMDVETEREKVSEDTRVTPSSVIDLQEEIQSELRIESSRSDAIPEPHLETTDRDTSYSPVIRIKDEPIDEDYDKALMPESDLSRIKQELDGSDNNETEASSASDELRISSVYSVSGNSSDAVSASVAPSQQSSFSVISQSAASLRGTTILLPAQAQTPLQLQLQHKAQMHSQIQAQARMQPPMMAQAQLQAVPPQPPQIHAPPPTVRICCSGCSKVLQKGQTAFQRKGSNQLFCSTVCLTSFSLPSVQFTPIIAPKKTCHLCLKVIVNLKDLITIPVGSMNTLKEFCSQACLSIYRDRYEDAPPDLFTHCNVCKLVKEIQHEVTHLGAVHKLCSDECFARFRSSRNLYMSYCENCGNCKASGNYHLVQIDDSIKKFCCVECIANYKQKSGKRLHCPYCQDIRNIDQMMEGTNIQGVTEFFCSQRCVALSQASPSLTGTAFPCTSCKKVVIPQYHLAISDGSIRNFCSLDCVGKFQEKLNSPVPHNQMNGTSHTPQPQSAVPPPPRPTADHLQPIQNSSSTSHNPPPPPPPLPPPPPFVPPSNPNPVPTYVPAPGVMNSQDTQQQQQWPSKPPSSSDPMRLTCRQCQNHFSSKPEVFQFKGHAGLFCSRACCDTYKKEGNVKALCEYCKLEKVVKDIITYEKQPRSFCCEGCKLLFKHELAKRHGGQCRVCAYCQNMTHKTIQNFFGGKLEEFCTEECMSLYTVLFYEMAKCSGCKNQGSLKESLVWDGVTRHFCNLSCLLQFCSKCITPHQPLSNGTVSNTTTVQAPLSLSKDMPVIGGVVSLASTLPGNTALTGALPTSNASSKNIGEASTQTDAAVGAIPHRRMLKNKALMCRPITEEQGVQCQPEPPVPPNMSEKVINENGEIVRYVPVPVPIPMPVYIPVPMHLYTQYTPFPMGFPLPVPVPMVIPGPQDAPEQKDTKCSLPAQSSVEDDEPEKGKDKPASHDQGSTYSGDLESEAQSTPLSWAETEDAGASVKPAVPATEAEEPSAEAEDHTPPTTNLTKEQPDLENDFPLTTADPGSAKENRLVLTLKRRKRGRDGHPPRKRGRKRSGTDTSSSVWLSTSSSKLNQTYGVEAWASWVRMKRGHAEQEQQAPEPMTMKEDVLQCSSADLSYGLCRFIKEVRRPNGEEYQPDSIYYLCLGIQQCLLENERLENIFTDPLYNQFITDITTLLKDWVNKVSPGGYMHSRVEEEYLWECKQLGALSPIVLLNTLLFFGSKLLNLKTVEEHRRLAFSNVSHCSKTTKSGLTSYLRFRLPNKEEEKEKKSPAGKRKRDEESVEEEFLEMPENVENPLRCPVRLYEFYLSKCSNSVKQRPDLFYLQPEASCHPSSPVWYSAQPLDSTMMESMLTRILAIQDIHLDSKHQQKYLDSSDEESS", "length": 1456, "header": "tr|E7FA89-1|E7FA89_DANRE Isoform 1 of Zinc finger MYM-type protein 4 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-266o15.1 PE=1 SV=1 CANONICAL=E7FA89-1" }, "locus": {} }, { "isoform_ac": "X1WH87-1", "url": "https://www.uniprot.org/uniprotkb/E7FA89/entry#X1WH87-1", "sequence": { "sequence": "MDQPSELEVKSSGDQGESSSGQLGDEELDGLPVFGTDEDDWEVDSSFAQKAFSQTDGNSNDKNDAAATEENSSSANEEMDVETEREKVSEDTRVTPSSVIDLQEEIQSELRIESSRSDAIPEPHLETTDRDTSYSPVIRIKDEPIDEDYDKALMPESDLSRIKQELDGSDNNETEASSASDELRISSVYSVSGNSSDAVSASVAPSQQSSFSVISQSAASLRGTTILLPAQAQTPLQLQLQHKAQMHSQIQAQARMQPPMMAQAQLQAVPPQPPQIHAPPPTVRICCSGCSKVLQKGQTAFQRKGSNQLFCSTVCLTSFSLPSVQFTPIIAPKKTCHLCLKVIVNLKDLITIPVGSMNTLKEFCSQACLSIYRDRYEDAPPDLFTHCNVCKLVKEIQHEVTHLGAVHKLCSDECFARFRSSRNLYMSYCENCGNCKASGNYHLVQIDDSIKKFCCVECIANYKQKSGKRLHCPYCQDIRNIDQMMEGTNIQGVTEFFCSQRCVALSQASPSLTGTAFPCTSCKKVVIPQYHLAISDGSIRNFCSLDCVGKFQEKLNSPVPHNQMNGTSHTPQPQSAVPPPPRPTADHLQPIQNSSSTSHNPPPPPPPLPPPPPFVPPSNPNPVPTYVPAPGVMNSQDTQQQQQWPSKPPSSSDPMRLTCRQCQNHFSSKPEVFQFKGHAGLFCSRACCDTYKKEGNVKALCEYCKLEKVVKDIITYEKQPRSFCCEGCKLLFKHELAKRHGGQCRVCAYCQNMTHKTIQNFFGGKLEEFCTEECMSLYTVLFYEMAKCSGCKNQGSLKESLVWDGVTRHFCNLSCLLQFCSKCITPHQPLSNGTVSNTTTVQAPLSLSKDMPVIGGVVSLASTLPGNTALTGALPTSNASSKNIGEASTQTDAAVGAIPHRRMLKNKALMCRPITEEQGVQCQPEPPVPPNMSEKVINENGEIVRYVPVPVPIPMPVYIPVPMHLYTQYTPFPMGFPLPVPVPMVIPGPQDAPEQKDTKCSLPAQSSVEDDEPEKGKDKPASHDQGSTYSGDLESEAQSTPLSWAETEDAGASVKPAVPATEAEEPSAEAEDHTPPTTNLTKEQPDLENDFPLTTADPGSAKENRLVLTLKRRKRGRDGHPPRKRGRKRSGTDTSSSVWLSTSSSKLNQTYGVEAWASWVRMKRGHAEQEQQAQPMTMKEDVLQCSSADLSYGLCRFIKEVRRPNGEEYQPDSIYYLCLGIQQCLLENERLENIFTDPLYNQFITDITTLLKDWVNKVSPGGYMHSRVEEEYLWECKQLGALSPIVLLNTLLFFGSKLLNLKTVEEHRRLAFSNVSHCSKTTKSGLTSYLRFRLPNKEEEKEKKSPAGKRKRDEESVEEEFLEMPENVENPLRCPVRLYEFYLSKCSNSVKQRPDLFYLQPEASCHPSSPVWYSAQPLDSTMMESMLTRILAIQDIHLDSKHQQKYLDSSDEESS", "length": 1455, "header": "tr|X1WH87-1|E7FA89_DANRE Computationally mapped isoform of Zinc finger MYM-type protein 4 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-266o15.1 PE=1 SV=1 CANONICAL=E7FA89-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:560900", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560900", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7FA89", "url": "https://www.uniprot.org/uniprotkb/E7FA89" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1079, "end_pos": 1081, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1148, "end_pos": 1150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1315, "end_pos": 1317, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 194, "end_pos": 196, "annotation": "n_glycosylation_sequon" }, { "start_pos": 565, "end_pos": 567, "annotation": "n_glycosylation_sequon" }, { "start_pos": 593, "end_pos": 595, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 812, "end_pos": 814, "annotation": "n_glycosylation_sequon" }, { "start_pos": 832, "end_pos": 834, "annotation": "n_glycosylation_sequon" }, { "start_pos": 837, "end_pos": 839, "annotation": "n_glycosylation_sequon" }, { "start_pos": 878, "end_pos": 880, "annotation": "n_glycosylation_sequon" }, { "start_pos": 931, "end_pos": 933, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FA89", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FA89" }, { "id": "SM00746", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00746" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TRASH", "eco_id": "ECO_0000259", "start_pos": 287, "end_pos": 323, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1079, "end_pos": 1081 }, { "start_pos": 1148, "end_pos": 1150 }, { "start_pos": 1315, "end_pos": 1317 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 194, "end_pos": 196 }, { "start_pos": 565, "end_pos": 567 }, { "start_pos": 593, "end_pos": 595 }, { "start_pos": 71, "end_pos": 73 }, { "start_pos": 752, "end_pos": 754 }, { "start_pos": 812, "end_pos": 814 }, { "start_pos": 832, "end_pos": 834 }, { "start_pos": 837, "end_pos": 839 }, { "start_pos": 878, "end_pos": 880 }, { "start_pos": 931, "end_pos": 933 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E9QBC3-1", "uniprot_ac": "E9QBC3", "uniprot_id": "E9QBC3_DANRE", "mass": { "chemical_mass": 86449.0, "monoisotopic_mass": 86449.0 }, "refseq": { "ac": "XP_690486", "name": "centrosomal protein of 85 kDa isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690486" }, "gene_names": [ { "name": "cep85", "type": "recommended", "evidence": [ { "id": "E9QBC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QBC3" } ] }, { "name": "cep85", "type": "synonym", "evidence": [ { "id": "XP_690486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690486" } ] } ], "protein_names": [ { "name": "Centrosomal protein of 85 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "E9QBC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QBC3/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 85 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "XP_690486", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690486" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_690486.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_690486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690486" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QBC3", "url": "https://www.uniprot.org/uniprotkb/E9QBC3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cep85", "url": "https://www.uniprot.org/uniprotkb/E9QBC3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-1998", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1998", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000060215", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000060215", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "561994", "url": "https://www.ncbi.nlm.nih.gov/gene/561994", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058190", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058190", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561994", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561994", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMFSVPQ", "url": "https://omabrowser.org/oma/group/RMFSVPQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2B4L3", "url": "https://www.orthodb.org/?gene=A0A8M2B4L3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AJE9", "url": "https://www.orthodb.org/?gene=A0A8M3AJE9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E9QBC3", "url": "https://www.orthodb.org/?gene=E9QBC3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31075", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31075", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31075:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31075:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF24555", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24555", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_690486", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690486", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B4L3", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B4L3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B4L3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B4L3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AJE9", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AJE9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AJE9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AJE9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HKV3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HKV3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HKV3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HKV3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QBC3", "url": "https://www.uniprot.org/uniprotkb/E9QBC3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QBC3-1", "url": "https://www.uniprot.org/uniprotkb/E9QBC3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-1998", "url": "https://zfin.org/ZDB-GENE-030131-1998", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTTSQKYQSSELTGLSDMEWATPAVSEKFQSRFGWRPSKVDSGDMGLGTFDHTEEICSSRSSPCFQPIRSQIPIPTAHVMPSTAGALASKLKPHSSEEGRTTSSSSSSKSSLSKSASSPNLDAQHDENLDTTSVKPDCLSRYRSLVNGLDHSLFPSGDQTRLDEPQKFDVPTMEPTLNQSALLGGLYPDVCQQLQLTGPADNAGLHDQTYKVLPESRACPVDPYSQRSMYSGSGTSARMFSIPQGLQTQALLRDQACTYDQLLQERCGELASWQQQKQKLETLRLQVEQMQLMTGGSGQYLPLYPSAAHTENSKWDAVIKANENLLKDKELTIERQKQQMSQLEQRLRESELQVHSALMGRGAPYTDVCLLRLQEAQRENAFLRAQFAERNNCFTKDKLEADRRLGAVETEMQRLNEVLKESSEKHAEELKKQEERIRSRDKHINGLKKKCQKEAEQNREKQQRIETLERYLADLPTMEDYQAQHKKLEEVEERAAELQSTVKDLEVQLEAAHTAVRNKETQLEEQRRKERELLTTVTSLQNRVQESLEDGVRLPSLDIEKLREENTALKDEQQRLKKVIEKQLRMMEQLGSQIRTLEEQISQEECISQALRQETADKEQNLLQLRSAMKELSVQNQELMEHNLTLQERLQGEEPSSGCGLLPAGARLTQRLHGEMAACLCDLRSLCNVLTQRAQGHDPNLSMLLGIASAPPPVAEQWDDWLSPEGLQKKLNEAQQLRRDVEELRTTVSDRYAQDMGENCITQ", "length": 763, "header": "tr|E9QBC3-1|E9QBC3_DANRE Isoform 1 of Centrosomal protein of 85 kDa isoform X1 OS=Danio rerio OX=7955 GN=cep85 PE=4 SV=1 CANONICAL=E9QBC3-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B4L3-1", "url": "https://www.uniprot.org/uniprotkb/E9QBC3/entry#A0A8M2B4L3-1", "sequence": { "sequence": "MPSTAGALASKLKPHSSEEGRTTSSSSSSKSSLSKSASSPNLDAQHDENLDTTSVKPDCLSRYRSLVNGLDHSLFPSGDQTRLDEPQKFDVPTMEPTLNQSALLGGLYPDVCQQLQLTGPADNAGLHDQTYKVLPESRACPVDPYSQRSMYSGSGTSARMFSIPQGLQTQALLRDQACTYDQLLQERCGELASWQQQKQKLETLRLQVEQMQLMTGGSGQYLPLYPSAAHTENSKWDAVIKANENLLKDKELTIERQKQQMSQLEQRLRESELQVHSALMGRGAPYTDVCLLRLQEAQRENAFLRAQFAERNNCFTKDKLEADRRLGAVETEMQRLNEVLKESSEKHAEELKKQEERIRSRDKHINGLKKKCQKEAEQNREKQQRIETLERYLADLPTMEDYQAQHKKLEEVEERAAELQSTVKDLEVQLEAAHTAVRNKETQLEEQRRKERELLTTVTSLQNRVQESLEDGVRLPSLDIEKLREENTALKDEQQRLKKVIEKQLRMMEQLGSQIRTLEEQISQEECISQALRQETADKEQNLLQLRSAMKELSVQNQELMEHNLTLQERLQGEEPSSGCGLLPAGARLTQRLHGEMAACLCDLRSLCNVLTQRAQGHDPNLSMLLGIASAPPPVAEQWDDWLSPEGLQKKLNEAQQLRRDVEELRTTVSDRYAQDMGENCITQ", "length": 684, "header": "tr|A0A8M2B4L3-1|E9QBC3_DANRE Computationally mapped isoform of Centrosomal protein of 85 kDa isoform X1 OS=Danio rerio OX=7955 GN=cep85 PE=4 SV=1 CANONICAL=E9QBC3-1" }, "locus": {} }, { "isoform_ac": "A0A8M3AJE9-1", "url": "https://www.uniprot.org/uniprotkb/E9QBC3/entry#A0A8M3AJE9-1", "sequence": { "sequence": "MTTSQKYQSSELTGLSDMEWATPAVSEKFQSRFGWRPSKVDSGDMGLGTFDHTEEICSSRSSPCFQPIRSQIPIPTAHVMPSTAGALASKLKPHSSEEGRTTSSSSSSKSSLSKSASSPNLDAQHDENLDTTSVKPDCLSRYRSLVNGLDHSLFPSGDQTRLDEPQKFDVPTMEPTLNQSALLGGLYPDVCQQLQLTGPADNAGLHDQTYKVLPESRACPVDPYSQRSMYSGSGTSARMFSIPQGLQTQALLRDQACTYDQLLQERCGELASWQQQKQKLETLRLQVEQMQLMTGGSGQYLPLYPSAAHTENSKWDAVIKANENLLKDKELTIERQKQQMSQLEQRLRESELQVHSALMGRGAPYTDVCLLRLQEAQRENAFLRAQFAERNNCFTKDKLEADRRLGAVETEMQRLNEVLKESSEKHAEELKKQEERIRSRDKHINGLKKKCQKEAEQNREKQQRIETLERYLADLPTMEDYQAQHKKLEEVEERAAELQSTVKDLEVQLEAAHTAVRNKETQLEEQRRKERELLTTVTSLQNRVQESLEDGVRLPSLDIEKLREENTALKDEQQRLKKVIEKQLRMMEQLGSQIRTLEEQISQEECISQALRQETADKEQNLLQLRSAMKELSVQNQELMEHNLTLQERLQGEEPSSGCGLLPAGARLTQRLHGEMAACLCDLRSLCNVLTQRAQGHDPNLSMLLGIASPPPVAEQWDDWLSPEGLQKKLNEAQQLRRDVEELRTTVSDRYAQDMGENCITQ", "length": 762, "header": "tr|A0A8M3AJE9-1|E9QBC3_DANRE Computationally mapped isoform of Centrosomal protein of 85 kDa isoform X1 OS=Danio rerio OX=7955 GN=cep85 PE=4 SV=1 CANONICAL=E9QBC3-1" }, "locus": {} }, { "isoform_ac": "A0AC58HKV3-1", "url": "https://www.uniprot.org/uniprotkb/E9QBC3/entry#A0AC58HKV3-1", "sequence": { "sequence": "MPSTAGALASKLKPHSSEEGRTTSSSSSSKSSLSKSASSPNLDAQHDENLDTTSVKPDCLSRYRSLVNGLDHSLFPSGDQTRLDEPQKFDVPTMEPTLNQSALLGGLYPDVCQQLQLTGPADNAGLHDQTYKVLPESRACPVDPYSQRSMYSGSGTSARMFSIPQGLQTQALLRDQACTYDQLLQERCGELASWQQQKQKLETLRLQVEQMQLMTGGSGQYLPLYPSAAHTENSKWDAVIKANENLLKDKELTIERQKQQMSQLEQRLRESELQVHSALMGRGAPYTDVCLLRLQEAQRENAFLRAQFAERNNCFTKDKLEADRRLGAVETEMQRLNEVLKESSEKHAEELKKQEERIRSRDKHINGLKKKCQKEAEQNREKQQRIETLERYLADLPTMEDYQAQHKKLEEVEERAAELQSTVKDLEVQLEAAHTAVRNKETQLEEQRRKERELLTTVTSLQNRVQESLEDGVRLPSLDIEKLREENTALKDEQQRLKKVIEKQLRMMEQLGSQIRTLEEQISQEECISQALRQETADKEQNLLQLRSAMKELSVQNQELMEHNLTLQERLQGEEPSSGCGLLPAGARLTQRLHGEMAACLCDLRSLCNVLTQRAQGHDPNLSMLLGIASPPPVAEQWDDWLSPEGLQKKLNEAQQLRRDVEELRTTVSDRYAQDMGENCITQ", "length": 683, "header": "tr|A0AC58HKV3-1|A0AC58HKV3_DANRE Computationally mapped isoform of Centrosomal protein of 85 kDa isoform X4 OS=Danio rerio OX=7955 GN=cep85 PE=4 SV=1 CANONICAL=E9QBC3-1" }, "locus": {} }, { "isoform_ac": "E9QBC3-1", "url": "https://www.uniprot.org/uniprotkb/E9QBC3/entry#E9QBC3-1", "sequence": { "sequence": "MTTSQKYQSSELTGLSDMEWATPAVSEKFQSRFGWRPSKVDSGDMGLGTFDHTEEICSSRSSPCFQPIRSQIPIPTAHVMPSTAGALASKLKPHSSEEGRTTSSSSSSKSSLSKSASSPNLDAQHDENLDTTSVKPDCLSRYRSLVNGLDHSLFPSGDQTRLDEPQKFDVPTMEPTLNQSALLGGLYPDVCQQLQLTGPADNAGLHDQTYKVLPESRACPVDPYSQRSMYSGSGTSARMFSIPQGLQTQALLRDQACTYDQLLQERCGELASWQQQKQKLETLRLQVEQMQLMTGGSGQYLPLYPSAAHTENSKWDAVIKANENLLKDKELTIERQKQQMSQLEQRLRESELQVHSALMGRGAPYTDVCLLRLQEAQRENAFLRAQFAERNNCFTKDKLEADRRLGAVETEMQRLNEVLKESSEKHAEELKKQEERIRSRDKHINGLKKKCQKEAEQNREKQQRIETLERYLADLPTMEDYQAQHKKLEEVEERAAELQSTVKDLEVQLEAAHTAVRNKETQLEEQRRKERELLTTVTSLQNRVQESLEDGVRLPSLDIEKLREENTALKDEQQRLKKVIEKQLRMMEQLGSQIRTLEEQISQEECISQALRQETADKEQNLLQLRSAMKELSVQNQELMEHNLTLQERLQGEEPSSGCGLLPAGARLTQRLHGEMAACLCDLRSLCNVLTQRAQGHDPNLSMLLGIASAPPPVAEQWDDWLSPEGLQKKLNEAQQLRRDVEELRTTVSDRYAQDMGENCITQ", "length": 763, "header": "tr|E9QBC3-1|E9QBC3_DANRE Isoform 1 of Centrosomal protein of 85 kDa isoform X1 OS=Danio rerio OX=7955 GN=cep85 PE=4 SV=1 CANONICAL=E9QBC3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561994", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561994", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JUV7-1", "protein_name": "Centrosomal protein 85", "gene_name": "Cep85", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAMQEKYPSDRSPHTASPGSNVIQKGSSLGTEWQTPVISEAFRSRFSRCSSIADSGDTAIGTSCSDIAEDFCSSSGSPSFQPIKSHITIPTAHVMPSTLGASPAKPSPTPSGPSSAKLPLSGLTEGVGMTRNGDFGAVKRSPGLSRDFMYLPSAAGENGIQQSWFPAVGHEREGEMRKFDVSSMESTLNQPAMLETLYSDPHYRAHFPTPRPDTNKDAYKVLPESKKAPGSGAVFERNGPHASNSGVLPLGLQPAPGLSKSLSSQVWQPSPDPWHPGEQSCELSTCRQQLELIRLQMEQMQLQNGAICHHPAAFTPSLPTLEPAQWISILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSKEKMELEKKLSASEVEIQLIRESLKVTLQKHSEEGKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQTEQLKDAELKNTELQGRVAELETMLEDTQAACREKEVQLESLRQREAQFSSARHSFQDKQSLEEASGESLKVEMESQQKECDSLRKIVERQQLKLEQLHSQVQSQKQELAQEEGISQALREEAQRRETALQQMRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSSSGSPDAAQLAYELHQELASCLQDLQAVCSIVTQRAQGHSPNLSLLLGIHSTPHPGTQLDLQKPDVIRRKLEEVQQLRHDIEDLRTSLSDRYAQDMGENCATQ", "length": 763 }, "evidence": [ { "id": "MGI:1917262", "url": "https://alliancegenome.org/gene/MGI:1917262#orthology", "database": "AGR" }, { "id": "HGNC:25309", "url": "https://alliancegenome.org/gene/HGNC:25309#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P2H3-1", "protein_name": "Centrosomal protein of 85 kDa", "gene_name": "CEP85", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAMQEKYPTEGISHVTSPSSDVIQKGSSLGTEWQTPVISEPFRSRFSRCSSVADSGDTAIGTSCSDIAEDFCSSSGSPPFQPIKSHVTIPTAHVMPSTLGTSPAKPNSTPVGPSSSKLPLSGLAESVGMTRNGDLGAMKHSPGLSRDLMYFSGATGENGIEQSWFPAVGHERQEEARKFDIPSMESTLNQSAMMETLYSDPHHRVRFHNPRTSTSKELYRVLPEAKKAPGSGAVFERNGPHSNSSGVLPLGLQPAPGLSKPLPSQVWQPSPDTWHPREQSCELSTCRQQLELIRLQMEQMQLQNGAICHHPAAFGPSLPILEPAQWISILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSREKIDLEKKLSASEVEVQLIRESLKVALQKHSEEVKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQSQQLKDSELKSTELQEKVTELESLLEETQAICREKEIQLESLRQREAEFSSAGHSLQDKQSVEETSGEGPEVEMESWQKRYDSLQKIVEKQQQKMDQLRSQVQSLEQEVAQEEGTSQALREEAQRRDSALQQLRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSPPSPDTAQLALELHQELASCLQDLQAVCSIVTQRAQGHDPNLSLLLGIHSAQHPETQLDLQKPDVIKRKLEEVQQLRRDIEDLRTTMSDRYAQDMGENCVTQ", "length": 762 }, "evidence": [ { "id": "MGI:1917262", "url": "https://alliancegenome.org/gene/MGI:1917262#orthology", "database": "AGR" }, { "id": "HGNC:25309", "url": "https://alliancegenome.org/gene/HGNC:25309#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1998", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1998#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BMK0-1", "protein_name": "Centrosomal protein of 85 kDa", "gene_name": "Cep85", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMQEKYPNDRSHATSPGSNVIQKGSSLGTEWQTPVISETFRSRFSRCSSIADSGDTAIGTSCSDIAEDFCSSSGSPSFQPIKSHITIPTAHVMPSTLGASPAKPNSAPSGPSSAKLPLSGLTEGVGMTRNGDFGAVKRSPGLARDFMYLPSAAGENGSQQSWFPAVGHEREGEMRKFDVPSMESTLNQPAMLETLYSDPHYRAHFPNPRPDTNKDVYKVLPESKKAPGSGAVFERNGPHASSSGVLPLGLQPAPGLSKSLSSQVWQPSPDPWHPGEQSCELSTCRQQLELIRLQMEQMQLQNGAMCHHPAAFAPLLPTLEPAQWLSILNSNEHLLKEKELLIDKQRKHISQLEQKVRESELQVHSALLGRPAPFGDVCLLRLQELQRENTFLRAQFAQKTEALSKEKMELEKKLSASEVEIQLIRESLKVTLQKHSEEGKKQEERVKGRDKHINNLKKKCQKESEQNREKQQRIETLERYLADLPTLEDHQKQTEQLKDAELKNTELQERVAELETLLEDTQATCREKEVQLESLRQREADLSSARHSFQDKQSVEEANGENLRVDMESQQKECDSLRKMVERQQLKMEQLHSQVQSQKQELAQEEGINQALREEAQRRETALQQMRTAVKELSVQNQDLIEKNLTLQEHLRQAQPGSSSSPDSAQLACELHQELASCLQDLQAVCSIVTQRAQGHNPNLSLLLGIHSTQHPGTQLDLQKPDVIRRKLEEVQQLRHDIEDLRTSLSDRYAQDMGENCATQ", "length": 761 }, "evidence": [ { "id": "MGI:1917262", "url": "https://alliancegenome.org/gene/MGI:1917262#orthology", "database": "AGR" }, { "id": "HGNC:25309", "url": "https://alliancegenome.org/gene/HGNC:25309#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1998", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1998#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "E9QBC3", "url": "https://www.uniprot.org/uniprotkb/E9QBC3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 178, "end_pos": 180, "annotation": "n_glycosylation_sequon" }, { "start_pos": 643, "end_pos": 645, "annotation": "n_glycosylation_sequon" }, { "start_pos": 700, "end_pos": 702, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E9QBC3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QBC3" }, { "id": "PF24555", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24555" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Centrosomal protein of 85 kDa-like CC4 coiled-coil", "eco_id": "ECO_0000259", "start_pos": 564, "end_pos": 647, "start_aa": "Glu", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 178, "end_pos": 180 }, { "start_pos": 643, "end_pos": 645 }, { "start_pos": 700, "end_pos": 702 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FCK0-1", "uniprot_ac": "E7FCK0", "uniprot_id": "E7FCK0_DANRE", "mass": { "chemical_mass": 38246.0, "monoisotopic_mass": 38246.0 }, "refseq": { "ac": "NP_957364", "name": "LIM and cysteine-rich domains protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957364" }, "gene_names": [ { "name": "lmcd1", "type": "recommended", "evidence": [ { "id": "E7FCK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCK0" } ] }, { "name": "lmcd1", "type": "synonym", "evidence": [ { "id": "NP_957364", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957364" } ] }, { "name": "zgc:56533", "type": "synonym", "evidence": [ { "id": "NP_957364", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957364" }, { "id": "E7FCK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCK0" } ] } ], "protein_names": [ { "name": "LIM and cysteine-rich domains protein 1", "type": "synonym", "evidence": [ { "id": "NP_957364", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957364" }, { "id": "E7FCK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCK0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQQ01021697.1, GFIL01047023.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Apr 18, 2011 this sequence version replaced NP_957364.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_957364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957364" } ] } ], "disease": [ { "disease_id": "DOID:4248", "recommended_name": { "id": "DOID:4248", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4248", "name": "coronary stenosis", "description": "" }, "synonyms": [ { "id": "DOID:4248", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4248", "name": "Coronary artery stenosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "4248", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4248" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FCK0", "url": "https://www.uniprot.org/uniprotkb/E7FCK0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "lmcd1", "url": "https://www.uniprot.org/uniprotkb/E7FCK0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040426-1067", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1067", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000002002", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000002002", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09340", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09340", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09829", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09829", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "394045", "url": "https://www.ncbi.nlm.nih.gov/gene/394045", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010442", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010442", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033724", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033724", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047120", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047120", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:394045", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:394045", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HDALWHP", "url": "https://omabrowser.org/oma/group/HDALWHP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AMI6", "url": "https://www.orthodb.org/?gene=A0A8M3AMI6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FCK0", "url": "https://www.orthodb.org/?gene=E7FCK0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24211:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24211:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF06297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-5683826", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5683826", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_957364", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_957364", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3AMI6", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AMI6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AMI6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AMI6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FCK0", "url": "https://www.uniprot.org/uniprotkb/E7FCK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FCK0-1", "url": "https://www.uniprot.org/uniprotkb/E7FCK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040426-1067", "url": "https://zfin.org/ZDB-GENE-040426-1067", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSKGPLPAGKGAACLTCKGICPGFQPHSWRKACVKCQCSQDEHAFISNNEDDLKVGRLLADSRYTHLTAKVKGGDGTRVYKRNRMIVTNPVVSRKDPTFNTVTYDWAPTGLTQKLAMLYMSLLPEERRPVAGTEGSLYRHKQLTRQLPAYDHDPAYCHSLSEAELKVMAQFVKSYKEESLGVGEVALPGEKSTTKRNEKISQEQPDPPLTEQTPDGAIESPVSNETEYYCSGCGQLAAMDEPVVYADRAGYERLWHPACFVCGECGEALVDLIYFWKEGALLCGRHYCQSIRPRCLGCDELIFSDMLLQEASGHVWHKEHFCCWLCGQDIRVECGCDKRQTT", "length": 342, "header": "tr|E7FCK0-1|E7FCK0_DANRE Isoform 1 of LIM and cysteine-rich domains protein 1 OS=Danio rerio OX=7955 GN=lmcd1 PE=4 SV=1 CANONICAL=E7FCK0-1" }, "isoforms": [ { "isoform_ac": "A0A8M3AMI6-1", "url": "https://www.uniprot.org/uniprotkb/E7FCK0/entry#A0A8M3AMI6-1", "sequence": { "sequence": "MSKGPLPAGKGAACLTCKGICPGFQPHSWRKACVKCQCSQDEHAFISNNEDDLKAMLYMSLLPEERRPVAGTEGSLYRHKQLTRQLPAYDHDPAYCHSLSEAELKVMAQFVKSYKEESLGVGEVALPGEKSTTKRNEKISQEQPDPPLTEQTPDGAIESPVSNETEYYCSGCGQLAAMDEPVVYADRAGYERLWHPACFVCGECGEALVDLIYFWKEGALLCGRHYCQSIRPRCLGCDELIFSDMLLQEASGHVWHKEHFCCWLCGQDIRVECGCDKRQTT", "length": 281, "header": "tr|A0A8M3AMI6-1|E7FCK0_DANRE Computationally mapped isoform of LIM and cysteine-rich domains protein 1 OS=Danio rerio OX=7955 GN=lmcd1 PE=4 SV=1 CANONICAL=E7FCK0-1" }, "locus": {} }, { "isoform_ac": "E7FCK0-1", "url": "https://www.uniprot.org/uniprotkb/E7FCK0/entry#E7FCK0-1", "sequence": { "sequence": "MSKGPLPAGKGAACLTCKGICPGFQPHSWRKACVKCQCSQDEHAFISNNEDDLKVGRLLADSRYTHLTAKVKGGDGTRVYKRNRMIVTNPVVSRKDPTFNTVTYDWAPTGLTQKLAMLYMSLLPEERRPVAGTEGSLYRHKQLTRQLPAYDHDPAYCHSLSEAELKVMAQFVKSYKEESLGVGEVALPGEKSTTKRNEKISQEQPDPPLTEQTPDGAIESPVSNETEYYCSGCGQLAAMDEPVVYADRAGYERLWHPACFVCGECGEALVDLIYFWKEGALLCGRHYCQSIRPRCLGCDELIFSDMLLQEASGHVWHKEHFCCWLCGQDIRVECGCDKRQTT", "length": 342, "header": "tr|E7FCK0-1|E7FCK0_DANRE Isoform 1 of LIM and cysteine-rich domains protein 1 OS=Danio rerio OX=7955 GN=lmcd1 PE=4 SV=1 CANONICAL=E7FCK0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Genetic association analyses highlight biological pathways underlying mitral valve prolapse.", "journal": "Nat. Genet.", "date": "2015", "authors": "Dina C, Bouatia-Naji N, Tucker N, Delling FN, Toomer K, Durst R, Perrocheau M, Fernandez-Friera L, Solis J, Le Tourneau T, Chen MH, Probst V, Bosse Y, Pibarot P, Zelenika D, Lathrop M, Hercberg S, Roussel R, Benjamin EJ, Bonnet F, Lo SH, Dolmatova E, Simonet F, Lecointe S, Kyndt F, Redon R, Le Marec H, Froguel P, Ellinor PT, Vasan RS, Bruneval P, Markwald RR, Norris RA, Milan DJ, Slaugenhaupt SA, Levine RA, Schott JJ, Hagege AA, Jeunemaitre X", "evidence": [ { "database": "UniProtKB", "id": "E7FCK0", "url": "https://www.uniprot.org/uniprotkb/E7FCK0" } ], "reference": [ { "type": "PubMed", "id": "26301497", "url": "https://glygen.org/publication/PubMed/26301497" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7FCK0", "url": "https://www.uniprot.org/uniprotkb/E7FCK0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Expression of Protein-Coding Gene Orthologs in Zebrafish and Mouse Inner Ear Non-sensory Supporting Cells.", "journal": "Front. Neurosci.", "date": "2019", "authors": "Giffen Kimberlee P, Liu Huizhan, Kramer Kenneth L, He David Z", "evidence": [ { "database": "UniProtKB", "id": "E7FCK0", "url": "https://www.uniprot.org/uniprotkb/E7FCK0" } ], "reference": [ { "type": "PubMed", "id": "31680844", "url": "https://glygen.org/publication/PubMed/31680844" } ] } ], "pathway": [ { "id": "dre:394045", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:394045", "resource": "KEGG Pathway" }, { "id": "R-DRE-5683826", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5683826", "resource": "Reactome", "description": "Surfactant metabolism" } ], "orthologs": [ { "uniprot_canonical_ac": "A1ZAT5-1", "protein_name": "Testin", "gene_name": "Tes", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSAVSPNSCVETPKAPEWLSKLESRREQLKRSKLGHEAGAGAPCAECKDKCPGLDLHFWRKVCRNCKCPKIQHVCPDDDDATGWAQFEILGQIRAKPAYIKIKALASQPVQLEWVPPNAAPDVVTDYMEKLGTAQIPVAGSDAALKRKMQLELQVPPHDLDAALCDGLTETEAIQLQQYVQKLREQCVGQGVVVRLGDRLNHAQVEHVAPALMPTQEAQQTWQSLGLMPVADDTLNELLANPKVAQALASPASAHPKLLVAFSEPLCESTAQFEENGALRAQTREKLLGISKPALLSLVTHGIVYDKVLGILQEKKLNISRDPKLGPIAEFRKEYVNNPQFRAEINTICPQPPMTPIKSPPGTPFNSPLPLKNPVQIRMGAQMRQDTPMRRVKFGGVSTIVYDCGLPANTDYDRDPVFAQILQAEPLKHAFQEARAGRAPSSVVISNIPAPVASLAELRGLNPATRAQLQSVGLDKNMLQSAVSNAPYYDRLFRSLHDKGISHDQCHLLQPMKQVHDWLLDDDQLLDEIDKVFADMANGCKDISYPKPSLGELPTSQSSDSGFHSKPPTPGYGSEDLTAGQGRFASIPGIEDMNMYPSCAGMPEQFQQLRLHGDEASGKNSTRTILCADCNQPIAMGEVAVKADRAGKEIAWHPGCFKCITCRELLADLVYFFHQGQVFCGRDLAIRLKIPRCRACDELIFTKEYTAAEEATFHIKHFCCYQCDEPLAGQQYIADEKSNMPLCLLCYDRLFAVRCQRCKVAIGPADQGVAWGDVHWHASCFVCAGVQCSKPLIGGRFCVKENMPFCSPTCVRSLIN", "length": 816 }, "evidence": [ { "id": "HGNC:6633", "url": "https://alliancegenome.org/gene/HGNC:6633#orthology", "database": "AGR" }, { "id": "MGI:1353635", "url": "https://alliancegenome.org/gene/MGI:1353635#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q17QE2-1", "protein_name": "LIM and cysteine-rich domains protein 1", "gene_name": "LMCD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAKVAKDLNPRVQKMSLGQQQSARGVPCLRCKGTCSGFEPHSWRKICKSCKCSQEDHCLSSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGALYRRRQLMHQLPIYDQDPSRCRGLLENELKVMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETAPPTTNGSIGDPSKEYVCELCKGVAPADSPVVYSDRAGYSKQWHPACFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFSEDYQRVEDLAWHRKHFVCEGCEQQLGGRAYIVTMGQLLCPTCSKSKRS", "length": 363 }, "evidence": [ { "id": "E7FCK0", "url": "https://omabrowser.org/oma/group/E7FCK0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5PXT2-1", "protein_name": "LIM and cysteine-rich domains protein 1", "gene_name": "LMCD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAKVAKDLNPGVQKMSLGQQQSARGVPCLRCKGTCSGFEPHSWRKICKSCKCSQEDHFLSSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAYYRRRQLMHQLPIYDQDPSRCRGLLESELKVMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETAAPTANGSLGDPSKEYVCELCKGVAPADSPVVYSDRAGYSKQWHPACFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFSEDYQRVEDLAWHRKHFVCEGCEQQLGGRAYIITKGQLLCPTCSKSKRT", "length": 363 }, "evidence": [ { "id": "E7FCK0", "url": "https://omabrowser.org/oma/group/E7FCK0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q8VEE1-1", "protein_name": "LIM and cysteine-rich domains protein 1", "gene_name": "Lmcd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKVAKDLNPGVQKMSLGQQQSARGVACLRCKGMCSGFEPHSWRKICKSCKCSQEEHCLSSDLDDDRKIGRLLMDSKYATLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKERQPVTGTEGALYRRRQLMHQLPIYDQDPSRCRGLVENELKAMEEFVKHYKSEALGVGEVALPGQGGLPKEENKTQEKPEGTETTAPTTNGSLGDPSKEVEYVCELCKGAAPVDSPVVYADRAGYSKQWHPTCFQCIKCSEPLVDLIYFWKDGAPWCGRHYCESVRPRCSGCDEIIFSEDYQRVEDLAWHRKHFICEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS", "length": 365 }, "evidence": [ { "id": "HGNC:6633", "url": "https://alliancegenome.org/gene/HGNC:6633#orthology", "database": "AGR" }, { "id": "MGI:1353635", "url": "https://alliancegenome.org/gene/MGI:1353635#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1067", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1067#orthology", "database": "AGR" }, { "id": "E7FCK0", "url": "https://omabrowser.org/oma/group/E7FCK0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NZU5-1", "protein_name": "LIM and cysteine-rich domains protein 1", "gene_name": "LMCD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKVAKDLNPGVKKMSLGQLQSARGVACLGCKGTCSGFEPHSWRKICKSCKCSQEDHCLTSDLEDDRKIGRLLMDSKYSTLTARVKGGDGIRIYKRNRMIMTNPIATGKDPTFDTITYEWAPPGVTQKLGLQYMELIPKEKQPVTGTEGAFYRRRQLMHQLPIYDQDPSRCRGLLENELKLMEEFVKQYKSEALGVGEVALPGQGGLPKEEGKQQEKPEGAETTAATTNGSLSDPSKEVEYVCELCKGAAPPDSPVVYSDRAGYNKQWHPTCFVCAKCSEPLVDLIYFWKDGAPWCGRHYCESLRPRCSGCDEIIFAEDYQRVEDLAWHRKHFVCEGCEQLLSGRAYIVTKGQLLCPTCSKSKRS", "length": 365 }, "evidence": [ { "id": "HGNC:6633", "url": "https://alliancegenome.org/gene/HGNC:6633#orthology", "database": "AGR" }, { "id": "MGI:1353635", "url": "https://alliancegenome.org/gene/MGI:1353635#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1067", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1067#orthology", "database": "AGR" }, { "id": "E7FCK0", "url": "https://omabrowser.org/oma/group/E7FCK0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7FCK0", "url": "https://www.uniprot.org/uniprotkb/E7FCK0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7FCK0", "url": "https://www.uniprot.org/uniprotkb/E7FCK0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 224, "end_pos": 226, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FCK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCK0" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 228, "end_pos": 293, "start_aa": "Tyr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7FCK0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCK0" }, { "id": "PS51303", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51303" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PET", "eco_id": "ECO_0000259", "start_pos": 85, "end_pos": 192, "start_aa": "Met", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 224, "end_pos": 226 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E9QC53-1", "uniprot_ac": "E9QC53", "uniprot_id": "E9QC53_DANRE", "mass": { "chemical_mass": 77392.0, "monoisotopic_mass": 77392.0 }, "refseq": { "ac": "XP_001334616", "name": "uncharacterized protein troap isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001334616" }, "gene_names": [ { "name": "troap", "type": "recommended", "evidence": [ { "id": "E9QC53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QC53" } ] }, { "name": "troap", "type": "synonym", "evidence": [ { "id": "XP_001334616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001334616" } ] } ], "protein_names": [ { "name": "Uncharacterized protein troap isoform X1", "type": "synonym", "evidence": [ { "id": "E9QC53", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QC53/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein troap isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001334616", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001334616" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001334616.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001334616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001334616" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QC53", "url": "https://www.uniprot.org/uniprotkb/E9QC53" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "troap", "url": "https://www.uniprot.org/uniprotkb/E9QC53", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-1968", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1968", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000094977", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000094977", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "795944", "url": "https://www.ncbi.nlm.nih.gov/gene/795944", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026133", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026133", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:795944", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795944", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LHFEESM", "url": "https://omabrowser.org/oma/group/LHFEESM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AN25", "url": "https://www.orthodb.org/?gene=A0A8M3AN25", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E9QC53", "url": "https://www.orthodb.org/?gene=E9QC53", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15289", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15289", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15289:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15289:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_001334616", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001334616", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3AN25", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AN25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AN25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AN25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILS7", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILS7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILS7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILS7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILT8", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58ILT8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58ILT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QC53", "url": "https://www.uniprot.org/uniprotkb/E9QC53", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QC53-1", "url": "https://www.uniprot.org/uniprotkb/E9QC53-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-1968", "url": "https://zfin.org/ZDB-GENE-030131-1968", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSSNPLRAQNRSQQDQTGMLKSQDLRTKPSASSTKRGSENLDPSASAEAGKVVSKLKGVSRLPVLAKSLQPALSELSQNPNHNKWEQRPLAGKAQKKKTCTKPVPFNLSQSRTRIQKSTDVSQGKPPLMPSARLTTAEKLRDLNAGAKTDTQSHKTTTPGVLRTQANKSPRLQSFNNVHYKNSTDGHGCYNQTDLSSRLDCIHLSQSKHPEHSSHLSKASLSKVDVNSENQAPKDKHCFQTVPSTAQSHVSYKGSSQNLSSAVHNVFSREGLSAVGAQCMMPRLSTCPSGPGASNNLPQRVLKKTHHGVDATADKAGLFSPDPSALRSILQSDGTRLAEHTGATPRVSTCPTGRGTSIYSAQRVPVKKPQTEVSAAVKAPAGSAVSFSPDPAALRSILLNEGVRAGGATPSRVSVCPTGRGTSIYSAQRVPVKKNKQEVMVTAAVSSQCANRTPVMKWTPQRVTNTKPQSMRKLCTTQKMSSLRDSPGFLGSHDPSPGTLMCQEGEKVVQRLFEEQEQMDDDQTDQNGIASQQLLNSHQSVEAKSTVTENSDSNLHHTKNEGKKTAQPFIQAAHRGSVIVFSSSQRLVSEHSQDRLKTLAANLQLCEDRPTSHNAAQSNGSQINPSVDMTKQSQSKAAITKSSAVSALRRRQTPLEEMFLDEECATYTSRLLSCPLQPRSGNPVASTLLFQDSTCFLPIGLSSPVRLSPVLSSGSIRA", "length": 719, "header": "tr|E9QC53-1|E9QC53_DANRE Isoform 1 of Uncharacterized protein troap isoform X1 OS=Danio rerio OX=7955 GN=troap PE=1 SV=1 CANONICAL=E9QC53-1" }, "isoforms": [ { "isoform_ac": "A0A8M3AN25-1", "url": "https://www.uniprot.org/uniprotkb/E9QC53/entry#A0A8M3AN25-1", "sequence": { "sequence": "MSSSNPLRAQNRSQQDQTGMLKSQDLRTKPSASSTKRGSENLDPSASAEAGKVVSKLKGVSRLPVLAKSLQPALSELSQNPNHNKWEQRPLAGKAQKKKTCTKPVPFNLSQSRTRIQKSTDVSQGKPPLMPSARLTTAEKLRDLNAGAKTDTQSHKTTTPGVLRTQANKSPRLQSFNNVHYKNSTDGHGCYNQTDLSSRLDCIHLSQSKHPEHSSHLSKASLSKVDVNSENQAPKDKHCFQTVPSTAQSHVSYKGSSQNLSSAVHNVFSREGLSAVGAQCMMPRLSTCPSGPGASNNLPQRVLKKTHHGVDATADKAGLFSPDPSALRSILQSDGTRLAEHTGATPRVSTCPTGRGTSIYSAQRVPVKKPQTEVSAAVKAPAGSAVSFSPDPAALRSILLNEGVRAGGATPSRVSVCPTGRGTSIYSAQRVPVKKNKQEVMVTAAVSSQCANRTPVMKWTPQRVTNTKPQSMRKLCTTQKMSSLRDSPGFLGSHDPSPGTLMCQEGEKVVQRLFEEQEQMDDDQTDQNGIASQQLLNSHQSVEAKSTVTENSDSNLHHTKNEGKKTAQPFIQAAHRGSVIVFSSSQRLVSEHSQDRLKTLAANLQLCEDRPTSHNAAQSNGSQINPSVDMTKQSQSKAITKSSAVSALRRRQTPLEEMFLDEECATYTSRLLSCPLQPRSGNPVASTLLFQDSTCFLPIGLSSPVRLSPVLSSGSIRA", "length": 718, "header": "tr|A0A8M3AN25-1|E9QC53_DANRE Computationally mapped isoform of Uncharacterized protein troap isoform X1 OS=Danio rerio OX=7955 GN=troap PE=1 SV=1 CANONICAL=E9QC53-1" }, "locus": {} }, { "isoform_ac": "A0AC58ILS7-1", "url": "https://www.uniprot.org/uniprotkb/E9QC53/entry#A0AC58ILS7-1", "sequence": { "sequence": "MSSSNPLRAQNRSQQDQTGMLKSQDLRTKPSASSTKRGSENLDPSASAEAGKVVSKLKGVSRLPVLAKSLQPALSELSQNPNHNKWEQRPLAGKAQKKKTCTKPVPFNLSQSRTRIQKSTDVSQGKPPLMPSARLTTAEKLRDLNAGSSQNLSSAVHNVFSREGLSAVGAQCMMPRLSTCPSGPGASNNLPQRVLKKTHHGVDATADKAGLFSPDPSALRSILQSDGTRLAEHTGATPRVSTCPTGRGTSIYSAQRVPVKKPQTEVSAAVKAPAGSAVSFSPDPAALRSILLNEGVRAGGATPSRVSVCPTGRGTSIYSAQRVPVKKNKQEVMVTAAVSSQCANRTPVMKWTPQRVTNTKPQSMRKLCTTQKMSSLRDSPGFLGSHDPSPGTLMCQEGEKVVQRLFEEQEQMDDDQTDQNGIASQQLLNSHQSVEAKSTVTENSDSNLHHTKNEGKKTAQPFIQAAHRGSVIVFSSSQRLVSEHSQDRLKTLAANLQLCEDRPTSHNAAQSNGSQINPSVDMTKQSQSKAAITKSSAVSALRRRQTPLEEMFLDEECATYTSRLLSCPLQPRSGNPVASTLLFQDSTCFLPIGLSSPVRLSPVLSSGSIRA", "length": 611, "header": "tr|A0AC58ILS7-1|A0AC58ILS7_DANRE Computationally mapped isoform of Uncharacterized protein troap isoform X3 OS=Danio rerio OX=7955 GN=troap PE=1 SV=1 CANONICAL=E9QC53-1" }, "locus": {} }, { "isoform_ac": "A0AC58ILT8-1", "url": "https://www.uniprot.org/uniprotkb/E9QC53/entry#A0AC58ILT8-1", "sequence": { "sequence": "MSSSNPLRAQNRSQQDQTGMLKSQDLRTKPSASSTKRGSENLDPSASAEAGKVVSKLKGVSRLPVLAKSLQPALSELSQNPNHNKWEQRPLAGKAQKKKTCTKPVPFNLSQSRTRIQKSTDVSQGKPPLMPSARLTTAEKLRDLNAGSSQNLSSAVHNVFSREGLSAVGAQCMMPRLSTCPSGPGASNNLPQRVLKKTHHGVDATADKAGLFSPDPSALRSILQSDGTRLAEHTGATPRVSTCPTGRGTSIYSAQRVPVKKPQTEVSAAVKAPAGSAVSFSPDPAALRSILLNEGVRAGGATPSRVSVCPTGRGTSIYSAQRVPVKKNKQEVMVTAAVSSQCANRTPVMKWTPQRVTNTKPQSMRKLCTTQKMSSLRDSPGFLGSHDPSPGTLMCQEGEKVVQRLFEEQEQMDDDQTDQNGIASQQLLNSHQSVEAKSTVTENSDSNLHHTKNEGKKTAQPFIQAAHRGSVIVFSSSQRLVSEHSQDRLKTLAANLQLCEDRPTSHNAAQSNGSQINPSVDMTKQSQSKAITKSSAVSALRRRQTPLEEMFLDEECATYTSRLLSCPLQPRSGNPVASTLLFQDSTCFLPIGLSSPVRLSPVLSSGSIRA", "length": 610, "header": "tr|A0AC58ILT8-1|A0AC58ILT8_DANRE Computationally mapped isoform of Uncharacterized protein troap isoform X4 OS=Danio rerio OX=7955 GN=troap PE=1 SV=1 CANONICAL=E9QC53-1" }, "locus": {} }, { "isoform_ac": "E9QC53-1", "url": "https://www.uniprot.org/uniprotkb/E9QC53/entry#E9QC53-1", "sequence": { "sequence": "MSSSNPLRAQNRSQQDQTGMLKSQDLRTKPSASSTKRGSENLDPSASAEAGKVVSKLKGVSRLPVLAKSLQPALSELSQNPNHNKWEQRPLAGKAQKKKTCTKPVPFNLSQSRTRIQKSTDVSQGKPPLMPSARLTTAEKLRDLNAGAKTDTQSHKTTTPGVLRTQANKSPRLQSFNNVHYKNSTDGHGCYNQTDLSSRLDCIHLSQSKHPEHSSHLSKASLSKVDVNSENQAPKDKHCFQTVPSTAQSHVSYKGSSQNLSSAVHNVFSREGLSAVGAQCMMPRLSTCPSGPGASNNLPQRVLKKTHHGVDATADKAGLFSPDPSALRSILQSDGTRLAEHTGATPRVSTCPTGRGTSIYSAQRVPVKKPQTEVSAAVKAPAGSAVSFSPDPAALRSILLNEGVRAGGATPSRVSVCPTGRGTSIYSAQRVPVKKNKQEVMVTAAVSSQCANRTPVMKWTPQRVTNTKPQSMRKLCTTQKMSSLRDSPGFLGSHDPSPGTLMCQEGEKVVQRLFEEQEQMDDDQTDQNGIASQQLLNSHQSVEAKSTVTENSDSNLHHTKNEGKKTAQPFIQAAHRGSVIVFSSSQRLVSEHSQDRLKTLAANLQLCEDRPTSHNAAQSNGSQINPSVDMTKQSQSKAAITKSSAVSALRRRQTPLEEMFLDEECATYTSRLLSCPLQPRSGNPVASTLLFQDSTCFLPIGLSSPVRLSPVLSSGSIRA", "length": 719, "header": "tr|E9QC53-1|E9QC53_DANRE Isoform 1 of Uncharacterized protein troap isoform X1 OS=Danio rerio OX=7955 GN=troap PE=1 SV=1 CANONICAL=E9QC53-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 410, "start_aa": "Thr", "end_pos": 410, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr410", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:795944", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795944", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "B7ZNG4-1", "protein_name": "Tastin", "gene_name": "Troap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTTLQTNKDPHLRGVSPNPSKIPVLSQRCQDFSSVKSRSLDQENQDPRTPAQKPPRSTQRQRPLTDTAGLRSKTLHQTEKSPSLKTLRNPLEELKPSSGGSNVGLVTHPQTEAIGAIEFVADPAALATILSGEGVKSCPQGYRSSLAQRVLVRERKGGTTQRGQSARSSAYLAPRIPTHQVGPARASCFSRLEGPGLRDHTLSPPRLEALNPPPGSSHSSTRPSLQELRRETCGGGRDGDCTDRRTSASQASRLLLKTPVQPASLPLRGEQEAVPHSDDGGGRHHLGLAQRIPLKESLTNTRSTYSSMKRFAIRRKAQFTPLRSLPKVQQAQWLSGLSPHSSPEEPALPWRQIAMKLFDQESRITLQKEPRKPSVASTSGPRPKRTPSHQELRIQRINILQQLLQQEVEGLAMGDGAPLNGGSAFDMTELKLPTAEISRTLTASEHNSGAALVGLSQHSGATEPLLSEECEEPQAYPEETKAAQPCSTTELKPPVPHRAEPELPEPCLPALSGPPLPSCRGQAEPPMACPRTEPGASAACALEAGTPESSTQPCCNQGPPATASLTFSSQSPVCASPSIHSLYPTGYSGPSSLAPRTLALRQRLRACLDTIHSFQEAHLDDECAFYTSRAPPPGPTRVFTNPVVTTLEWQDALRFVPIGPVVPQDSPS", "length": 668 }, "evidence": [ { "id": "RGD:1306870", "url": "https://alliancegenome.org/gene/RGD:1306870#orthology", "database": "AGR" }, { "id": "MGI:1925983", "url": "https://alliancegenome.org/gene/MGI:1925983#orthology", "database": "AGR" }, { "id": "HGNC:12327", "url": "https://alliancegenome.org/gene/HGNC:12327#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1968", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1968#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZLZ9-1", "protein_name": "Trophinin associated protein", "gene_name": "Troap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTTLQTSKDPHLRGVSPNPSKIPVLSQRCSDFSSAKSGSLDQENQDPRRSAKKPLHRTQRPLTDTAGLRSKALHQTEKSQRLRITQPRNPLEELKPSSGGSNVGLTHPQTEASGAIEFVADPAALATILSGEGVKSCPLESRSSLAQRVLVRERKGGTHIQRGQSARSSAYLAPRIRAHQADPARASCFSRLEGPGLRDRTFSSQRSEALNPRAGSSFHSSARPSLQELRRETCGGSRDGSCTDSRTSASQASRLLLKTPVQPASLTLRGDHEAVPHSGGEGGPKLGLAQRVPLKESLTHTRTTYSSMKRFTTRRKTQFTPLRSLPRVQQAQWLSGLSPHSSPEEPALPWEQIAVKLFDQESLIALQKGPGKPSVASTSGPQSTRTPSHQELKMQRIHILQQLLRQEVEGLATGNCAALNGGSALDTTERQPPVAEDSSTLSAPAHKSETPLALPEHSGVTEALPAEEREEPQACPGEDTKESQPCSTTELKPPVPHRAEPEPPAPCLPALAGPPLPSCRGQAEPPEARPGIQLGASAASALQAGNPESSPEPCCSQGPPAATSLTSTQSPVCASFPIHSLHSSRSPTGRSGPSSVAPRTLALRQRLRACLTTIHCFHEARLDDECAFYTSRALPPGPTRVCTNPVATMLEWQDALRFIPVGPVAPQDSPS", "length": 671 }, "evidence": [ { "id": "RGD:1306870", "url": "https://alliancegenome.org/gene/RGD:1306870#orthology", "database": "AGR" }, { "id": "MGI:1925983", "url": "https://alliancegenome.org/gene/MGI:1925983#orthology", "database": "AGR" }, { "id": "HGNC:12327", "url": "https://alliancegenome.org/gene/HGNC:12327#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1968", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1968#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q12815-1", "protein_name": "Tastin", "gene_name": "TROAP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTRQATKDPLLRGVSPTPSKIPVRSQKRTPFPTVTSCAVDQENQDPRRWVQKPPLNIQRPLVDSAGPRPKARHQAETSQRLVGISQPRNPLEELRPSPRGQNVGPGPPAQTEAPGTIEFVADPAALATILSGEGVKSCHLGRQPSLAKRVLVRGSQGGTTQRVQGVRASAYLAPRTPTHRLDPARASCFSRLEGPGPRGRTLCPQRLQALISPSGPSFHPSTRPSFQELRRETAGSSRTSVSQASGLLLETPVQPAFSLPKGEREVVTHSDEGGVASLGLAQRVPLRENREMSHTRDSHDSHLMPSPAPVAQPLPGHVVPCPSPFGRAQRVPSPGPPTLTSYSVLRRLTVQPKTRFTPMPSTPRVQQAQWLRGVSPQSCSEDPALPWEQVAVRLFDQESCIRSLEGSGKPPVATPSGPHSNRTPSLQEVKIQRIGILQQLLRQEVEGLVGGQCVPLNGGSSLDMVELQPLLTEISRTLNATEHNSGTSHLPGLLKHSGLPKPCLPEECGEPQPCPPAEPGPPEAFCRSEPEIPEPSLQEQLEVPEPYPPAEPRPLESCCRSEPEIPESSRQEQLEVPEPCPPAEPRPLESYCRIEPEIPESSRQEQLEVPEPCPPAEPGPLQPSTQGQSGPPGPCPRVELGASEPCTLEHRSLESSLPPCCSQWAPATTSLIFSSQHPLCASPPICSLQSLRPPAGQAGLSNLAPRTLALRERLKSCLTAIHCFHEARLDDECAFYTSRAPPSGPTRVCTNPVATLLEWQDALCFIPVGSAAPQGSP", "length": 778 }, "evidence": [ { "id": "RGD:1306870", "url": "https://alliancegenome.org/gene/RGD:1306870#orthology", "database": "AGR" }, { "id": "MGI:1925983", "url": "https://alliancegenome.org/gene/MGI:1925983#orthology", "database": "AGR" }, { "id": "HGNC:12327", "url": "https://alliancegenome.org/gene/HGNC:12327#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1968", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1968#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 452, "end_pos": 454, "annotation": "n_glycosylation_sequon" }, { "start_pos": 620, "end_pos": 622, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 410 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 11, "end_pos": 13 }, { "start_pos": 168, "end_pos": 170 }, { "start_pos": 183, "end_pos": 185 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 452, "end_pos": 454 }, { "start_pos": 620, "end_pos": 622 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F4P5-1", "uniprot_ac": "E7F4P5", "uniprot_id": "E7F4P5_DANRE", "mass": { "chemical_mass": 62936.0, "monoisotopic_mass": 62936.0 }, "refseq": { "ac": "XP_686163", "name": "tripartite motif-containing protein 16 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686163" }, "gene_names": [ { "name": "ftr58", "type": "recommended", "evidence": [ { "id": "E7F4P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F4P5" } ] }, { "name": "ftr58", "type": "synonym", "evidence": [ { "id": "XP_686163", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686163" } ] } ], "protein_names": [ { "name": "Tripartite motif-containing protein 16 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F4P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F4P5/entry#names_and_taxonomy" } ] }, { "name": "tripartite motif-containing protein 16 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_686163", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686163" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_686163.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_686163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686163" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F4P5", "url": "https://www.uniprot.org/uniprotkb/E7F4P5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ftr58", "url": "https://www.uniprot.org/uniprotkb/E7F4P5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080219-44", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080219-44", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000071238", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000071238", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19769", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19769", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "557916", "url": "https://www.ncbi.nlm.nih.gov/gene/557916", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:557916", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557916", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "INSCWDE", "url": "https://omabrowser.org/oma/group/INSCWDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3ANE5", "url": "https://www.orthodb.org/?gene=A0A8M3ANE5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F4P5", "url": "https://www.orthodb.org/?gene=E7F4P5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-5656169", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5656169", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_686163", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686163", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3ANE5", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ANE5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3ANE5-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ANE5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INT3", "url": "https://www.uniprot.org/uniprotkb/A0AC58INT3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INT3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INT3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INV1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INV1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INV1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INV1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F4P5", "url": "https://www.uniprot.org/uniprotkb/E7F4P5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F4P5-1", "url": "https://www.uniprot.org/uniprotkb/E7F4P5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080219-44", "url": "https://zfin.org/ZDB-GENE-080219-44", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAEARIFVDQNEFMCSVCLDLLKDPVAIHCGHSYCKSCITDHWNQEDEKKVYSCPQCRETFKPRPALAKNTILAEMVEKLKKTKPSADVYAGAGDVQCDVCTKPKYKAIKSCLVCQESYCRTHFERHEEFHSRKPHKVIDATERLQDMICHKHEKHLELYCITDLQYICVICKEYEHKNHKIVSAAAERTEKQKELKEMQMKLQQRVLQRHKDLQQLRGAVETQKRSAQTAVEETEKIFIEIIRYIERQCSELKQMIRDQQKTAVRDAEGLIERLEQEINDLRRRDAELEQLSQTQDDMHFLQRFQSFSAPPESTDFQTSPLGSQFSFVGLRESVRQLKVKLEDLCKEEVKKITDRDTFTNTVPETRNDFLQYSHNFTLDPNTVNKYLCLSENKRVITDIDAVQSYPDHPDRFDDWRQVLCRESVCGRCYWEIEWSGKVLISVSYKSISRKGGGNDCGFGQNDQSWALFCSSDRYSFRRNKTDTDLPVKSISSRVGVYVNHSAGTLSFYSISDTMSLIHTVQTQFSQPLYPGFGVYGSVKLC", "length": 542, "header": "tr|E7F4P5-1|E7F4P5_DANRE Isoform 1 of Tripartite motif-containing protein 16 isoform X1 OS=Danio rerio OX=7955 GN=ftr58 PE=4 SV=1 CANONICAL=E7F4P5-1" }, "isoforms": [ { "isoform_ac": "A0A8M3ANE5-1", "url": "https://www.uniprot.org/uniprotkb/E7F4P5/entry#A0A8M3ANE5-1", "sequence": { "sequence": "MAEARIFVDQNEFMCSVCLDLLKDPVAIHCGHSYCKSCITDHWNQEDEKKVYSCPQCRETFKPRPALAKNTILAEMVEKLKKTKPSADVYAGAGDVQCDVCTKPKYKAIKSCLVCQESYCRTHFERHEEFHSRKPHKVIDATERLQDMICHKHEKHLELYCITDLQYICVICKEYEHKNHKIVSAAAERTEKQKELKEMQMKLQQRVLQRHKDLQQLRGAVETQKRSAQTAVEETEKIFIEIIRYIERQCSELKQMIRDQQKTAVRDAEGLIERLEQEINDLRRRDAELEQLSQTQDDMHFLQRFQSFSAPPESTDFQTSPLGSQFSFVGLRESVRQLKVKLEDLCKEEVKKITDRDTFTNTVPETRNDFLQYSHNFTLDPNTVNKYLCLSENKRVITDIDAVQSYPDHPDRFDDWRQVLCRESVCGRCYWEIEWSDTHSDEIRQTLISQ", "length": 450, "header": "tr|A0A8M3ANE5-1|E7F4P5_DANRE Computationally mapped isoform of Tripartite motif-containing protein 16 isoform X1 OS=Danio rerio OX=7955 GN=ftr58 PE=4 SV=1 CANONICAL=E7F4P5-1" }, "locus": {} }, { "isoform_ac": "A0AC58INT3-1", "url": "https://www.uniprot.org/uniprotkb/E7F4P5/entry#A0AC58INT3-1", "sequence": { "sequence": "MAEARIFVDQNEFMCSVCLDLLKDPVAIHCGHSYCKSCITDHWNQEDEKKVYSCPQCRETFKPRPALAKNTILAEMVEKLKKTKPSADVYAGAGDVQCDVCTKPKYKAIKSCLVCQESYCRTHFERHEEFHSRKPHKVIDATERLQDMICHKHEKHLELYCITDLQYICVICKEYEHKNHKIVSAAAERTEKQKELKEMQMKLQQRVLQRHKDLQQLRGAVETQKTAVEETEKIFIEIIRYIERQCSELKQMIRDQQKTAVRDAEGLIERLEQEINDLRRRDAELEQLSQTQDDMHFLQRFQSFSAPPESTDFQTSPLGSQFSFVGLRESVRQLKVKLEDLCKEEVKKITDRDTFTNTVPETRNDFLQYSHNFTLDPNTVNKYLCLSENKRVITDIDAVQSYPDHPDRFDDWRQVLCRESVCGRCYWEIEWSGKVLISVSYKSISRKGGGNDCGFGQNDQSWALFCSSDRYSFRRNKTDTDLPVKSISSRVGVYVNHSAGTLSFYSISDTMSLIHTVQTQFSQPLYPGFGVYGSVKLC", "length": 538, "header": "tr|A0AC58INT3-1|A0AC58INT3_DANRE Computationally mapped isoform of Tripartite motif-containing protein 16 isoform X2 OS=Danio rerio OX=7955 GN=ftr58 PE=4 SV=1 CANONICAL=E7F4P5-1" }, "locus": {} }, { "isoform_ac": "A0AC58INV1-1", "url": "https://www.uniprot.org/uniprotkb/E7F4P5/entry#A0AC58INV1-1", "sequence": { "sequence": "MAEARIFVDQNEFMCSVCLDLLKDPVAIHCGHSYCKSCITDHWNQEDEKKVYSCPQCRETFKPRPALAKNTILAEMVEKLKKTKPSADVYAGAGDVQCDVCTKPKYKAIKSCLVCQESYCRTHFERHEEFHSRKPHKVIDATERLQDMICHKHEKHLELYCITDLQYICVICKEYEHKNHKIVSAAAERTEKQKELKEMQMKLQQRVLQRHKDLQQLRGAVETQKTAVEETEKIFIEIIRYIERQCSELKQMIRDQQKTAVRDAEGLIERLEQEINDLRRRDAELEQLSQTQDDMHFLQRFQSFSAPPESTDFQTSPLGSQFSFVGLRESVRQLKVKLEDLCKEEVKKITDRDTFTNTVPETRNDFLQYSHNFTLDPNTVNKYLCLSENKRVITDIDAVQSYPDHPDRFDDWRQVLCRESVCGRCYWEIEWSDTHSDEIRQTLISQ", "length": 446, "header": "tr|A0AC58INV1-1|A0AC58INV1_DANRE Computationally mapped isoform of Tripartite motif-containing protein 16 isoform X4 OS=Danio rerio OX=7955 GN=ftr58 PE=4 SV=1 CANONICAL=E7F4P5-1" }, "locus": {} }, { "isoform_ac": "E7F4P5-1", "url": "https://www.uniprot.org/uniprotkb/E7F4P5/entry#E7F4P5-1", "sequence": { "sequence": "MAEARIFVDQNEFMCSVCLDLLKDPVAIHCGHSYCKSCITDHWNQEDEKKVYSCPQCRETFKPRPALAKNTILAEMVEKLKKTKPSADVYAGAGDVQCDVCTKPKYKAIKSCLVCQESYCRTHFERHEEFHSRKPHKVIDATERLQDMICHKHEKHLELYCITDLQYICVICKEYEHKNHKIVSAAAERTEKQKELKEMQMKLQQRVLQRHKDLQQLRGAVETQKRSAQTAVEETEKIFIEIIRYIERQCSELKQMIRDQQKTAVRDAEGLIERLEQEINDLRRRDAELEQLSQTQDDMHFLQRFQSFSAPPESTDFQTSPLGSQFSFVGLRESVRQLKVKLEDLCKEEVKKITDRDTFTNTVPETRNDFLQYSHNFTLDPNTVNKYLCLSENKRVITDIDAVQSYPDHPDRFDDWRQVLCRESVCGRCYWEIEWSGKVLISVSYKSISRKGGGNDCGFGQNDQSWALFCSSDRYSFRRNKTDTDLPVKSISSRVGVYVNHSAGTLSFYSISDTMSLIHTVQTQFSQPLYPGFGVYGSVKLC", "length": 542, "header": "tr|E7F4P5-1|E7F4P5_DANRE Isoform 1 of Tripartite motif-containing protein 16 isoform X1 OS=Danio rerio OX=7955 GN=ftr58 PE=4 SV=1 CANONICAL=E7F4P5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:557916", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557916", "resource": "KEGG Pathway" }, { "id": "R-DRE-5656169", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-5656169", "resource": "Reactome", "description": "Termination of translesion DNA synthesis" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7F4P5", "url": "https://www.uniprot.org/uniprotkb/E7F4P5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7F4P5", "url": "https://www.uniprot.org/uniprotkb/E7F4P5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "E7F4P5", "url": "https://www.uniprot.org/uniprotkb/E7F4P5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 376, "end_pos": 378, "annotation": "n_glycosylation_sequon" }, { "start_pos": 480, "end_pos": 482, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F4P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F4P5" }, { "id": "PS50119", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50119" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B box-type", "eco_id": "ECO_0000259", "start_pos": 145, "end_pos": 185, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7F4P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F4P5" }, { "id": "PS50188", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50188" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "B30.2/SPRY", "eco_id": "ECO_0000259", "start_pos": 357, "end_pos": 542, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7F4P5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F4P5" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 58, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 376, "end_pos": 378 }, { "start_pos": 480, "end_pos": 482 }, { "start_pos": 500, "end_pos": 502 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1Q5D2-1", "uniprot_ac": "F1Q5D2", "uniprot_id": "F1Q5D2_DANRE", "mass": { "chemical_mass": 143867.0, "monoisotopic_mass": 143867.0 }, "refseq": { "ac": "XP_005174417", "name": "UPF0606 protein KIAA1549L isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174417" }, "gene_names": [ { "name": "kiaa1549la", "type": "recommended", "evidence": [ { "id": "F1Q5D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2" } ] }, { "name": "kiaa1549la", "type": "synonym", "evidence": [ { "id": "XP_005174417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174417" } ] } ], "protein_names": [ { "name": "UPF0606 protein KIAA1549L isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005174417", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174417" }, { "id": "F1Q5D2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005174417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174417" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q5D2", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "kiaa1549la", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061207-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-55", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000062477", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000062477", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "566592", "url": "https://www.ncbi.nlm.nih.gov/gene/566592", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024606", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024606", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566592", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566592", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RYPQGSP", "url": "https://omabrowser.org/oma/group/RYPQGSP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3APP2", "url": "https://www.orthodb.org/?gene=A0A8M3APP2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AZN1", "url": "https://www.orthodb.org/?gene=A0A8M3AZN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1Q5D2", "url": "https://www.orthodb.org/?gene=F1Q5D2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21590", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21590", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21590:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21590:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12877", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12877", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005174417", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005174417", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3APP2", "url": "https://www.uniprot.org/uniprotkb/A0A8M3APP2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3APP2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3APP2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AZN1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AZN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AZN1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AZN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IXX1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IXX1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IXX1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IXX1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IXX4", "url": "https://www.uniprot.org/uniprotkb/A0AC58IXX4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IXX4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IXX4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IXX7", "url": "https://www.uniprot.org/uniprotkb/A0AC58IXX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IXX7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IXX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IXX9", "url": "https://www.uniprot.org/uniprotkb/A0AC58IXX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IXX9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IXX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IXY5", "url": "https://www.uniprot.org/uniprotkb/A0AC58IXY5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IXY5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IXY5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q5D2", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q5D2-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061207-55", "url": "https://zfin.org/ZDB-GENE-061207-55", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAPSNARNNFYILGSGCGNGKAGTQRTSEWIGLSLCRKYVDGVWTKCLISIGITLLLVPSIFAIDDEAKLEASGQAFSPSQDPTAAPNTTVSSSLLEGEDLALQFHSSPERAESTREQPVFTSVQTLQVAETHSLPSLPSNSDNRTNQKSPGELDVRVPNPPSPAEKINSVLTTSSDETLSEFPRNPDLPTAPGSSFTTLAETDATLTDNVTTSASISASNATSPERPENGSSATTVQSNSHTVTSDSLQLTTVTTTTVTPLTVTSMTVTPPTPVVMVKEVETTMPTTTTTQTTTTETEPPTTSTTTTTTTTTTTTTTKVAPTTTKPPTTTLATTTTTTMTTPQTTTVSTSGSTMTELSTSPTDSSLVCNVTERLWVKTVLSIQMRRNRLEPGMRQNLSKGFTQALQKAFNDSNIRIQMEKDICTPSNVTVGYFVMRGKAVLVASVVIDTLVSYGFDKILTDIREYVPVVLAIPNPVASWLPTLGIHLQLKTVLRFVGPADNIKSCGFIQMMEQRLENVFAEAQEKVEDSYGTLSVEILNTYQTGNSLAVTLVYVVWNGSSPLNGTVSSGLLNQLTAELVGYFLFFPPLIIAEPLEYHNLNTSVATRDYWVITVIQDVDSSSLEGSYQSFASLMEQRLAELFLVASRHGLRFRRATTVGDYTVQMVSIRRLSGPKNPAELTYYIQMNGSPITGTTAAKTLNTVDSQTMALTLGYFIQIQAEAVVKSMPSNVWILAVLIPVSLVIVVVIMAAAIICRRNRTVFKTSAFRNFHPRTKTSYRRDGSYHHQPVQGFDYAKQHMGQTGEEAVTVTKDTLVLSLPVRDAPLTQDRVTTLQDGTASKRPQPTDMHLSRLPSEDGSLSSSGSGKLNTGRSSTARRSTIQKTPKEEQHARNDHYDSLTGSLRLITIKPMAAPLNYSYPDSSSHSQDSVILNGEVNMGLKQKSDIEHYRNKLRLKAKRKGYSDGPGSSGSGSGHMYSHRDRLRRENASLDLEDLRGPKEDRKPSTYVKYRRSDSHREPAYWSRQSLNTPSPVETEMDMLVMRERSRRGIRNSGYDGEPEPFEETDVDRLLSSLGFGGGHQVKGHSDSSTLSSQPSIDEVRQQMHLLLDNAFGLASAEPTPANHHHHHHHPHSAYNPSHGSPYLDGVTSAPGTMNHPSGALQRGSSFGPDMHQCSLPKPGFRFTQLPDMGLGSPPPLIPPRGGVPPGTSLRCSTPDMSLKPRVSEASEMSQHNGTPYLPINRAPFPAVTVDESMTSYSGNPMTAVYAISANRPGYSDYFVLSPPSSYRSPSWMSYPPEPEDLPHQWNDTVKNQCHLETIC", "length": 1319, "header": "tr|F1Q5D2-1|F1Q5D2_DANRE Isoform 1 of UPF0606 protein KIAA1549L isoform X1 OS=Danio rerio OX=7955 GN=kiaa1549la PE=4 SV=1 CANONICAL=F1Q5D2-1" }, "isoforms": [ { "isoform_ac": "A0A8M3APP2-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2/entry#A0A8M3APP2-1", "sequence": { "sequence": "MAPSNARNNFYILGSGCGNGKAGTQRTSEWIGLSLCRKYVDGVWTKCLISIGITLLLVPSIFAIDDEAKLEASGQAFSPSQDPTAAPNTTVSSSLLEGEDLALQFHSSPERAESTREQPVFTSVQTLQVAETHSLPSLPSNSDNRTNQKSPGELDVRVPNPPSPAEKINSVLTTSSDETLSEFPRNPDLPTAPGSSFTTLAETDATLTDNVTTSASISASNATSPERPENGSSATTVQSNSHTVTSDSLQLTTVTTTTVTPLTVTSMTVTPPTPVVMVKEVETTMPTTTTTQTTTTETEPPTTSTTTTTTTTTTTTTTKVAPTTTKPPTTTLATTTTTTMTTPQTTTVSTSGSTMTELSTSPTDSSLVCNVTERLWVKTVLSIQMRRNRLEPGMRQNLSKGFTQALQKAFNDSNIRIQMEKDICTPSNVTVGYFVMRGKAVLVASVVIDTLVSYGFDKILTDIREYVPVVLAIPNPVASWLPTLGIHLQLKTVLRFVGPADNIKSCGFIQMMEQRLENVFAEAQEKVEDSYGTLSVEILNTYQTGNSLAVTLVYVVWNGSSPLNGTVSSGLLNQLTAELVGYFLFFPPLIIAEPLEYHNLNTSVATRDYWVITVIQDVDSSSLEGSYQSFASLMEQRLAELFLVASRHGLRFRRATTVGDYTVQMVSIRRLSGPKNPAELTYYIQMNGSPITGTTAAKTLNTVDSQTMALTLGYFIQIQAEAVVKSMPSNVWILAVLIPVSLVIVVVIMAAAIICRRNRTVFKTSAFRNFHPRTKTSYRRDGSYHHQPVQGFDYAKQHMGQTGEEAVTVTKDTLVLSLPVRDAPLTQDRVTTLQDGTASKRPQPTDMHLRLPSEDGSLSSSGSGKLNTGRSSTARRSTIQKTPKEEQHARNDHYDSLTGSLRLITIKPMAAPLNYSYPDSSSHSQDSVILNGEVNMGLKQKSDIEHYRNKLRLKAKRKGYSDGPGSSGSGSGHMYSHRDRLRRENASLDLEDLRGPKEDRKPSTYVKYRRSDSHREPAYWSRQSLNTPSPVETEMDMLVMRERSRRGIRNSGYDGEPEPFEETDVDRLLSSLGFGGGHQVKGHSDSSTLSSQPSIDEVRQQMHLLLDNAFGLASAEPTPANHHHHHHHPHSAYNPSHGSPYLDGVTSAPGTMNHPSGALQRGSSFGPDMHQCSLPKPGFRFTQLPDMGLGSPPPLIPPRGGVPPGTSLRCSTPDMSLKPRVSEASEMSQHNGTPYLPINRAPFPAVTVDESMTSYSGNPMTAVYAISANRPGYSDYFVLSPPSSYRSPSWMSYPPEPEDLPHQWNDTVKNQCHLETIC", "length": 1318, "header": "tr|A0A8M3APP2-1|F1Q5D2_DANRE Computationally mapped isoform of UPF0606 protein KIAA1549L isoform X1 OS=Danio rerio OX=7955 GN=kiaa1549la PE=4 SV=1 CANONICAL=F1Q5D2-1" }, "locus": {} }, { "isoform_ac": "A0A8M3AZN1-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2/entry#A0A8M3AZN1-1", "sequence": { "sequence": "MAPSNARNNFYILGSGCGNGKAGTQRTSEWIGLSLCRKYVDGVWTKCLISIGITLLLVPSIFAIDDEAKLEASGQAFSPSQDPTAAPNTTVSSSLLEGEDLALQFHSSPERAESTREQPVFTSVQTLQVAETHSLPSLPSNSDNRTNQKSPGELDVRVPNPPSPAEKINSVLTTSSDETLSEFPRNPDLPTAPGSSFTTLAETDATLTDNVTTSASISASNATSPERPENGSSATTVQSNSHTVTSDSLQLTTVTTTTVTPLTVTSMTVTPPTPVVMVKEVETTMPTTTTTQTTTTETEPPTTSTTTTTTTTTTTTTTKVAPTTTKPPTTTLATTTTTTMTTPQTTTVSTSGSTMTELSTSPTDSSLVCNVTERLWVKTVLSIQMRRNRLEPGMRQNLSKGFTQALQKAFNDSNIRIQMEKDICTPSNVTVGYFVMRGKAVLVASVVIDTLVSYGFDKILTDIREYVPVVLAIPNPVASWLPTLGIHLQLKTVLRFVGPADNIKSCGFIQMMEQRLENVFAEAQEKVEDSYGTLSVEILNTYQTGNSLAVTLVYVVWNGSSPLNGTVSSGLLNQLTAELVGYFLFFPPLIIAEPLEYHNLNTSVATRDYWVITVIQDVDSSSLEGSYQSFASLMEQRLAELFLVASRHGLRFRRATTVGDYTVQMVSIRRLSGPKNPAELTYYIQMNGSPITGTTAAKTLNTVDSQTMALTLGYFIQIQAEAVVKSMPSNVWILAVLIPVSLVIVVVIMAAAIICRRNRTVFKTSAFRNFHPRTKPVQGFDYAKQHMGQTGEEAVTVTKDTLVLSLPVRDAPLTQDRVTTLQDGTASKRPQPTDMHLSRLPSEDGSLSSSGSGKLNTGRSSTARRSTIQKTPKEEQHARNDHYDSLTGSLRLITIKPMAAPLNYSYPDSSSHSQDSVILNGEVNMGLKQKSDIEHYRNKLRLKAKRKGYSDGPGSSGSGSGHMYSHRDRLRRENASLDLEDLRGPKEDRKPSTYVKYRRSDSHREPAYWSRQSLNTPSPVETEMDMLVMRERSRRGIRNSGYDGEPEPFEETDVDRLLSSLGFGGGHQVKGHSDSSTLSSQPSIDEVRQQMHLLLDNAFGLASAEPTPANHHHHHHHPHSAYNPSHGSPYLDGVTSAPGTMNHPSGALQRGSSFGPDMHQCSLPKPGFRFTQLPDMGLGSPPPLIPPRGGVPPGTSLRCSTPDMSLKPRVSEASEMSQHNGTPYLPINRAPFPAVTVDESMTSYSGNPMTAVYAISANRPGYSDYFVLSPPSSYRSPSWMSYPPEPEDLPHQWNDTVKNQCHLETIC", "length": 1307, "header": "tr|A0A8M3AZN1-1|F1Q5D2_DANRE Computationally mapped isoform of UPF0606 protein KIAA1549L isoform X1 OS=Danio rerio OX=7955 GN=kiaa1549la PE=4 SV=1 CANONICAL=F1Q5D2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IXX1-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2/entry#A0AC58IXX1-1", "sequence": { "sequence": "MTVTPPTPVVMVKEVETTMPTTTTTQTTTTETEPPTTSTTTTTTTTTTTTTTKVAPTTTKPPTTTLATTTTTTMTTPQTTTVSTSGSTMTELSTSPTDSSLVCNVTERLWVKTVLSIQMRRNRLEPGMRQNLSKGFTQALQKAFNDSNIRIQMEKDICTPSNVTVGYFVMRGKAVLVASVVIDTLVSYGFDKILTDIREYVPVVLAIPNPVASWLPTLGIHLQLKTVLRFVGPADNIKSCGFIQMMEQRLENVFAEAQEKVEDSYGTLSVEILNTYQTGNSLAVTLVYVVWNGSSPLNGTVSSGLLNQLTAELVGYFLFFPPLIIAEPLEYHNLNTSVATRDYWVITVIQDVDSSSLEGSYQSFASLMEQRLAELFLVASRHGLRFRRATTVGDYTVQMVSIRRLSGPKNPAELTYYIQMNGSPITGTTAAKTLNTVDSQTMALTLGYFIQIQAEAVVKSMPSNVWILAVLIPVSLVIVVVIMAAAIICRRNRTVFKTSAFRNFHPRTKPVQGFDYAKQHMGQTGEEAVTVTKDTLVLSLPVRDAPLTQDRVTTLQDGTASKRPQPTDMHLSRLPSEDGSLSSSGSGKLNTGRSSTARRSTIQKTPKEEQHARNDHYDSLTGSLRLITIKPMAAPLNYSYPDSSSHSQDSVILNGEVNMGLKQKSDIEHYRNKLRLKAKRKGYSDGPGSSGSGSGHMYSHRDRLRRENASLDLEDLRGPKEDRKPSTYVKYRRSDSHREPAYWSRQSLNTPSPVETEMDMLVMRERSRRGIRNSGYDGEPEPFEETDVDRLLSSLGFGGGHQVKGHSDSSTLSSQPSIDEVRQQMHLLLDNAFGLASAEPTPANHHHHHHHPHSAYNPSHGSPYLDGVTSAPGTMNHPSGALQRGSSFGPDMHQCSLPKPGFRFTQLPDMGLGSPPPLIPPRGGVPPGTSLRCSTPDMSLKPRVSEASEMSQHNGTPYLPINRAPFPAVTVDESMTSYSGNPMTAVYAISANRPGYSDYFVLSPPSSYRSPSWMSYPPEPEDLPHQWNDTVKNQCHLETIC", "length": 1041, "header": "tr|A0AC58IXX1-1|A0AC58IXX1_DANRE Computationally mapped isoform of UPF0606 protein KIAA1549L isoform X7 OS=Danio rerio OX=7955 GN=kiaa1549la PE=4 SV=1 CANONICAL=F1Q5D2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IXX4-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2/entry#A0AC58IXX4-1", "sequence": { "sequence": "MTVTPPTPVVMVKEVETTMPTTTTTQTTTTETEPPTTSTTTTTTTTTTTTTTKVAPTTTKPPTTTLATTTTTTMTTPQTTTVSTSGSTMTELSTSPTDSSLVCNVTERLWVKTVLSIQMRRNRLEPGMRQNLSKGFTQALQKAFNDSNIRIQMEKDICTPSNVTVGYFVMRGKAVLVASVVIDTLVSYGFDKILTDIREYVPVVLAIPNPVASWLPTLGIHLQLKTVLRFVGPADNIKSCGFIQMMEQRLENVFAEAQEKVEDSYGTLSVEILNTYQTGNSLAVTLVYVVWNGSSPLNGTVSSGLLNQLTAELVGYFLFFPPLIIAEPLEYHNLNTSVATRDYWVITVIQDVDSSSLEGSYQSFASLMEQRLAELFLVASRHGLRFRRATTVGDYTVQMVSIRRLSGPKNPAELTYYIQMNGSPITGTTAAKTLNTVDSQTMALTLGYFIQIQAEAVVKSMPSNVWILAVLIPVSLVIVVVIMAAAIICRRNRTVFKTSAFRNFHPRTKTSYRRDGSYHHQPVQGFDYAKQHMGQTGEEAVTVTKDTLVLSLPVRDAPLTQDRVTTLQDGTASKRPQPTDMHLRLPSEDGSLSSSGSGKLNTGRSSTARRSTIQKTPKEEQHARNDHYDSLTGSLRLITIKPMAAPLNYSYPDSSSHSQDSVILNGEVNMGLKQKSDIEHYRNKLRLKAKRKGYSDGPGSSGSGSGHMYSHRDRLRRENASLDLEDLRGPKEDRKPSTYVKYRRSDSHREPAYWSRQSLNTPSPVETEMDMLVMRERSRRGIRNSGYDGEPEPFEETDVDRLLSSLGFGGGHQVKGHSDSSTLSSQPSIDEVRQQMHLLLDNAFGLASAEPTPANHHHHHHHPHSAYNPSHGSPYLDGVTSAPGTMNHPSGALQRGSSFGPDMHQCSLPKPGFRFTQLPDMGLGSPPPLIPPRGGVPPGTSLRCSTPDMSLKPRVSEASEMSQHNGTPYLPINRAPFPAVTVDESMTSYSGNPMTAVYAISANRPGYSDYFVLSPPSSYRSPSWMSYPPEPEDLPHQWNDTVKNQCHLETIC", "length": 1052, "header": "tr|A0AC58IXX4-1|A0AC58IXX4_DANRE Computationally mapped isoform of UPF0606 protein KIAA1549L isoform X6 OS=Danio rerio OX=7955 GN=kiaa1549la PE=4 SV=1 CANONICAL=F1Q5D2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IXX7-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2/entry#A0AC58IXX7-1", "sequence": { "sequence": "MTVTPPTPVVMVKEVETTMPTTTTTQTTTTETEPPTTSTTTTTTTTTTTTTTKVAPTTTKPPTTTLATTTTTTMTTPQTTTVSTSGSTMTELSTSPTDSSLVCNVTERLWVKTVLSIQMRRNRLEPGMRQNLSKGFTQALQKAFNDSNIRIQMEKDICTPSNVTVGYFVMRGKAVLVASVVIDTLVSYGFDKILTDIREYVPVVLAIPNPVASWLPTLGIHLQLKTVLRFVGPADNIKSCGFIQMMEQRLENVFAEAQEKVEDSYGTLSVEILNTYQTGNSLAVTLVYVVWNGSSPLNGTVSSGLLNQLTAELVGYFLFFPPLIIAEPLEYHNLNTSVATRDYWVITVIQDVDSSSLEGSYQSFASLMEQRLAELFLVASRHGLRFRRATTVGDYTVQMVSIRRLSGPKNPAELTYYIQMNGSPITGTTAAKTLNTVDSQTMALTLGYFIQIQAEAVVKSMPSNVWILAVLIPVSLVIVVVIMAAAIICRRNRTVFKTSAFRNFHPRTKTSYRRDGSYHHQPVQGFDYAKQHMGQTGEEAVTVTKDTLVLSLPVRDAPLTQDRVTTLQDGTASKRPQPTDMHLSRLPSEDGSLSSSGSGKLNTGRSSTARRSTIQKTPKEEQHARNDHYDSLTGSLRLITIKPMAAPLNYSYPDSSSHSQDSVILNGEVNMGLKQKSDIEHYRNKLRLKAKRKGYSDGPGSSGSGSGHMYSHRDRLRRENASLDLEDLRGPKEDRKPSTYVKYRRSDSHREPAYWSRQSLNTPSPVETEMDMLVMRERSRRGIRNSGYDGEPEPFEETDVDRLLSSLGFGGGHQVKGHSDSSTLSSQPSIDEVRQQMHLLLDNAFGLASAEPTPANHHHHHHHPHSAYNPSHGSPYLDGVTSAPGTMNHPSGALQRGSSFGPDMHQCSLPKPGFRFTQLPDMGLGSPPPLIPPRGGVPPGTSLRCSTPDMSLKPRVSEASEMSQHNGTPYLPINRAPFPAVTVDESMTSYSGNPMTAVYAISANRPGYSDYFVLSPPSSYRSPSWMSYPPEPEDLPHQWNDTVKNQCHLETIC", "length": 1053, "header": "tr|A0AC58IXX7-1|A0AC58IXX7_DANRE Computationally mapped isoform of UPF0606 protein KIAA1549L isoform X5 OS=Danio rerio OX=7955 GN=kiaa1549la PE=4 SV=1 CANONICAL=F1Q5D2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IXX9-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2/entry#A0AC58IXX9-1", "sequence": { "sequence": "MAPSNARNNFYILGSGCGNGKAGTQRTSEWIGLSLCRKYVDGVWTKCLISIGITLLLVPSIFAIDDEAKLEASGQAFSPSQDPTAAPNTTVSSSLLEGEDLALQFHSSPERAESTREQPVFTSVQTLQVAETHSLPSLPSNSDNRTNQKSPGELDVRVPNPPSPAEKINSVLTTSSDETLSEFPRNPDLPTAPGSSFTTLAETDATLTDNVTTSASISASNATSPERPENGSSATTVQSNSHTVTSDSLQLTTVTTTTVTPLTVTSMTVTPPTPVVMVKEVETTMPTTTTTQTTTTETEPPTTSTTTTTTTTTTTTTTKVAPTTTKPPTTTLATTTTTTMTTPQTTTVSTSGSTMTELSTSPTDSSLVCNVTERLWVKTVLSIQMRRNRLEPGMRQNLSKGFTQALQKAFNDSNIRIQMEKDICTPSNVTVGYFVMRGKAVLVASVVIDTLVSYGFDKILTDIREYVPVVLAIPNPVASWLPTLGIHLQLKTVLRFVGPADNIKSCGFIQMMEQRLENVFAEAQEKVEDSYGTLSVEILNTYQTGNSLAVTLVYVVWNGSSPLNGTVSSGLLNQLTAELVGYFLFFPPLIIAEPLEYHNLNTSVATRDYWVITVIQDVDSSSLEGSYQSFASLMEQRLAELFLVASRHGLRFRRATTVGDYTVQMVSIRRLSGPKNPAELTYYIQMNGSPITGTTAAKTLNTVDSQTMALTLGYFIQIQAEAVVKSMPSNVWILAVLIPVSLVIVVVIMAAAIICRRNRTVFKTSAFRNFHPRTKPVQGFDYAKQHMGQTGEEAVTVTKDTLVLSLPVRDAPLTQDRVTTLQDGTASKRPQPTDMHLRLPSEDGSLSSSGSGKLNTGRSSTARRSTIQKTPKEEQHARNDHYDSLTGSLRLITIKPMAAPLNYSYPDSSSHSQDSVILNGEVNMGLKQKSDIEHYRNKLRLKAKRKGYSDGPGSSGSGSGHMYSHRDRLRRENASLDLEDLRGPKEDRKPSTYVKYRRSDSHREPAYWSRQSLNTPSPVETEMDMLVMRERSRRGIRNSGYDGEPEPFEETDVDRLLSSLGFGGGHQVKGHSDSSTLSSQPSIDEVRQQMHLLLDNAFGLASAEPTPANHHHHHHHPHSAYNPSHGSPYLDGVTSAPGTMNHPSGALQRGSSFGPDMHQCSLPKPGFRFTQLPDMGLGSPPPLIPPRGGVPPGTSLRCSTPDMSLKPRVSEASEMSQHNGTPYLPINRAPFPAVTVDESMTSYSGNPMTAVYAISANRPGYSDYFVLSPPSSYRSPSWMSYPPEPEDLPHQWNDTVKNQCHLETIC", "length": 1306, "header": "tr|A0AC58IXX9-1|A0AC58IXX9_DANRE Computationally mapped isoform of UPF0606 protein KIAA1549L isoform X4 OS=Danio rerio OX=7955 GN=kiaa1549la PE=4 SV=1 CANONICAL=F1Q5D2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IXY5-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2/entry#A0AC58IXY5-1", "sequence": { "sequence": "MTVTPPTPVVMVKEVETTMPTTTTTQTTTTETEPPTTSTTTTTTTTTTTTTTKVAPTTTKPPTTTLATTTTTTMTTPQTTTVSTSGSTMTELSTSPTDSSLVCNVTERLWVKTVLSIQMRRNRLEPGMRQNLSKGFTQALQKAFNDSNIRIQMEKDICTPSNVTVGYFVMRGKAVLVASVVIDTLVSYGFDKILTDIREYVPVVLAIPNPVASWLPTLGIHLQLKTVLRFVGPADNIKSCGFIQMMEQRLENVFAEAQEKVEDSYGTLSVEILNTYQTGNSLAVTLVYVVWNGSSPLNGTVSSGLLNQLTAELVGYFLFFPPLIIAEPLEYHNLNTSVATRDYWVITVIQDVDSSSLEGSYQSFASLMEQRLAELFLVASRHGLRFRRATTVGDYTVQMVSIRRLSGPKNPAELTYYIQMNGSPITGTTAAKTLNTVDSQTMALTLGYFIQIQAEAVVKSMPSNVWILAVLIPVSLVIVVVIMAAAIICRRNRTVFKTSAFRNFHPRTKPVQGFDYAKQHMGQTGEEAVTVTKDTLVLSLPVRDAPLTQDRVTTLQDGTASKRPQPTDMHLRLPSEDGSLSSSGSGKLNTGRSSTARRSTIQKTPKEEQHARNDHYDSLTGSLRLITIKPMAAPLNYSYPDSSSHSQDSVILNGEVNMGLKQKSDIEHYRNKLRLKAKRKGYSDGPGSSGSGSGHMYSHRDRLRRENASLDLEDLRGPKEDRKPSTYVKYRRSDSHREPAYWSRQSLNTPSPVETEMDMLVMRERSRRGIRNSGYDGEPEPFEETDVDRLLSSLGFGGGHQVKGHSDSSTLSSQPSIDEVRQQMHLLLDNAFGLASAEPTPANHHHHHHHPHSAYNPSHGSPYLDGVTSAPGTMNHPSGALQRGSSFGPDMHQCSLPKPGFRFTQLPDMGLGSPPPLIPPRGGVPPGTSLRCSTPDMSLKPRVSEASEMSQHNGTPYLPINRAPFPAVTVDESMTSYSGNPMTAVYAISANRPGYSDYFVLSPPSSYRSPSWMSYPPEPEDLPHQWNDTVKNQCHLETIC", "length": 1040, "header": "tr|A0AC58IXY5-1|A0AC58IXY5_DANRE Computationally mapped isoform of UPF0606 protein KIAA1549L isoform X8 OS=Danio rerio OX=7955 GN=kiaa1549la PE=4 SV=1 CANONICAL=F1Q5D2-1" }, "locus": {} }, { "isoform_ac": "F1Q5D2-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5D2/entry#F1Q5D2-1", "sequence": { "sequence": "MAPSNARNNFYILGSGCGNGKAGTQRTSEWIGLSLCRKYVDGVWTKCLISIGITLLLVPSIFAIDDEAKLEASGQAFSPSQDPTAAPNTTVSSSLLEGEDLALQFHSSPERAESTREQPVFTSVQTLQVAETHSLPSLPSNSDNRTNQKSPGELDVRVPNPPSPAEKINSVLTTSSDETLSEFPRNPDLPTAPGSSFTTLAETDATLTDNVTTSASISASNATSPERPENGSSATTVQSNSHTVTSDSLQLTTVTTTTVTPLTVTSMTVTPPTPVVMVKEVETTMPTTTTTQTTTTETEPPTTSTTTTTTTTTTTTTTKVAPTTTKPPTTTLATTTTTTMTTPQTTTVSTSGSTMTELSTSPTDSSLVCNVTERLWVKTVLSIQMRRNRLEPGMRQNLSKGFTQALQKAFNDSNIRIQMEKDICTPSNVTVGYFVMRGKAVLVASVVIDTLVSYGFDKILTDIREYVPVVLAIPNPVASWLPTLGIHLQLKTVLRFVGPADNIKSCGFIQMMEQRLENVFAEAQEKVEDSYGTLSVEILNTYQTGNSLAVTLVYVVWNGSSPLNGTVSSGLLNQLTAELVGYFLFFPPLIIAEPLEYHNLNTSVATRDYWVITVIQDVDSSSLEGSYQSFASLMEQRLAELFLVASRHGLRFRRATTVGDYTVQMVSIRRLSGPKNPAELTYYIQMNGSPITGTTAAKTLNTVDSQTMALTLGYFIQIQAEAVVKSMPSNVWILAVLIPVSLVIVVVIMAAAIICRRNRTVFKTSAFRNFHPRTKTSYRRDGSYHHQPVQGFDYAKQHMGQTGEEAVTVTKDTLVLSLPVRDAPLTQDRVTTLQDGTASKRPQPTDMHLSRLPSEDGSLSSSGSGKLNTGRSSTARRSTIQKTPKEEQHARNDHYDSLTGSLRLITIKPMAAPLNYSYPDSSSHSQDSVILNGEVNMGLKQKSDIEHYRNKLRLKAKRKGYSDGPGSSGSGSGHMYSHRDRLRRENASLDLEDLRGPKEDRKPSTYVKYRRSDSHREPAYWSRQSLNTPSPVETEMDMLVMRERSRRGIRNSGYDGEPEPFEETDVDRLLSSLGFGGGHQVKGHSDSSTLSSQPSIDEVRQQMHLLLDNAFGLASAEPTPANHHHHHHHPHSAYNPSHGSPYLDGVTSAPGTMNHPSGALQRGSSFGPDMHQCSLPKPGFRFTQLPDMGLGSPPPLIPPRGGVPPGTSLRCSTPDMSLKPRVSEASEMSQHNGTPYLPINRAPFPAVTVDESMTSYSGNPMTAVYAISANRPGYSDYFVLSPPSSYRSPSWMSYPPEPEDLPHQWNDTVKNQCHLETIC", "length": 1319, "header": "tr|F1Q5D2-1|F1Q5D2_DANRE Isoform 1 of UPF0606 protein KIAA1549L isoform X1 OS=Danio rerio OX=7955 GN=kiaa1549la PE=4 SV=1 CANONICAL=F1Q5D2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1119, "start_aa": "Thr", "end_pos": 1119, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1119", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 270, "start_aa": "Thr", "end_pos": 270, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr270", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 430, "start_aa": "Thr", "end_pos": 430, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr430", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:566592", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566592", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8VKG2-1", "protein_name": "RIKEN cDNA D430041D05 gene", "gene_name": "D430041D05Rik", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MCCCGGRCCWDSCCWLPSPGTAGPTPCILIPHLMWMLSFTGTDNLQIHVTPTSESFPLGKLLPISPTWPFLEVKSSSAADRFKNVLGQPPDNTTLLKLSQTPLPKAHRRTRAHVDFSSSPYQGSGHSASLDLAKDPTETLVQTRPEGGREAADMSGLPRTSMLPPLPTAPSATSSAVSPSQPLVGMPFLSKHPLRSDSSLLLPPPSSSSLAPDSPHSIPTPKPVQHPTKVPLFPQMTPADFSSGQSPVNVLNPFFHKTNLFPSRDAQTLIGTPRLDFSTSSTKQYSEPSLSESPRPAASPTPGVLSSIAEQDHLSLPSLAPGGLPGVTSSRSMWEEALSPVSTQPFRTSGPVRGRGAESLPIYLRTLAASYGAWAPRFQTAESVMTSRELAPVPPTNSFANWPHLSEVPESSRKPTLSPENKPSSLVPPPQPLTTLSQGQMVHPEAAPGSPLKGTGTPLSLLTVRQPNKDHASPAPVPEAPLSREGAHDEYLPDAATQLLSSKLPNPPPTIWTFPQQKEDRAAAIFWTNEKANGTTSLWALPTKEAPSRRAVTGSTSDFNTGRLSPLIMTALRTDLSPPGSPPSSALTTQAASPRSSGTKLESLAAVTSQSELPASASKQVTELPSSTDVHGLPTMGGTRKPAATDVFWSFLSAETASLATQSGISGSQQQTNHDVNTHTINSTHRELRPASVALPGGTTSAANALQSRNFKEIAGQLVAADSFNFQDPVLSPRTSQPLQPSEEAVVESHTDFPPTGKHARDFDTEMVHYYSSTSQNPMSQLPIRPAHPFWPTWPSLASAASLHQMLSDGTDAGSHISSDIYLSPGENGSPQFQSVLEYHSSTASPSVPTGAFSRTPSKVLRTSRRPKKWTGAATHTVETSVSSKGELSATAAATATTTLFLRRSSPAPLSAALTAKGTGSSSSNLAKSSLTTALAKNVTNKAASGPKVTAGTIHTAFPFTPTYMLARTAHSLSTHTAMQGATGSVSGLLSTTHLPKKPQAMHTGLPNPTRPDTPRASTPRPLTITAALTSMTASVKATRLPSLQTGNTDAAFPAVSTAMATTGRMASNLDCQMSHKFLVKTVFFLTQRRIQSSESLKLGVTKGLTQALRKAFHQNDVSAHVDILEYSHNVTVGYYATKGRLVYLPAVVMDVLGVYGVSNVTADLKQHTPNLQSVAVLASPWKPQPAGAFQLKTVLQFVSQSDNIQSCRFAQTMEQRLQKAFQDAERKVLSTRSNLTVQIVSTSNASQAVTLVYAVGNQSSFLNGTVASSLLSQLSAELVGFYLTYPPLTIAEPLEYPNLDTSETTRDYWVITVLQGVDNSLVGLHNQSFARVMEQRLAQLFMMSQQQGRRFKRATTLGSYTVQMVKMQRVPGPKDPAELTYYTLYNGKPLLGTAAAKILSTIDSQRMALTLHHVVLLQADPVVKNPPNNLWIIAAVLAPIAVVTIIIIIITAVLCRKNKNDFKPDTMINLPQRAKPVQGFDYAKQHLGQQGADEEVIPVTQETVVLPIPVRDTPQERDTAQDGSAIKTAKSTETRRSRSPSENGSVISNESGKPSSGRRSPQNGMTQQKVTKEESRKRNVTASDEEEGAGLFDSAGKAAADPFDTSSGSVQLIAIKPSALPVVHPASDRGQESSAALNGEVNKALKQKSDIEHYRNKLRLKAKRKGYYDFPPVEAGKGLAERKMYEKAPKEVEHVLDADPELCAPFAESKNRQQMKNSVYRSRQSLNSPSPGETEMDLLVTRERPRRGIRNSGYDTEPEIIEETNVDRVHEPRGYGRARQAKGHSETSTLSSQPSIDEVRQQMHMLLEEAFSLASAGHAGQSRHQETYGSTQHLPYSEVVTSAPGTMTRPRAGVQWVPTYRPEMYQYSLPRPAYRFSQLPEMVMGSPPPPVPPRTGPVAVASLRRSTSDIGSKTRMAESTGPEPTQLHDSASFAQVSRGPVSVTQLDQSALNYSGNTVPAVFAIPAANRPGFTGYFIPTPPSSYRSQAWMSYAGENELPSQWADSVPLPGYIEAYPRSRYQQSSPSRLPRQYSQPANLHPSLEQAPVPSAAASQQSLTENEPPDTPLTNISTAALVKAIREEVAKLAKKQTDMFEFQV", "length": 2099 }, "evidence": [ { "id": "MGI:2181743", "url": "https://alliancegenome.org/gene/MGI:2181743#orthology", "database": "AGR" }, { "id": "HGNC:24836", "url": "https://alliancegenome.org/gene/HGNC:24836#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-55#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8I6GJS5-1", "protein_name": "RIKEN cDNA D430041D05 gene like", "gene_name": "G2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALQEAKPQGPSKAGPAAREPRDRPREPGLCGAGGIAARCQGVKSSGARGSEDVLPLRPLLLGLLLLAALSGNCRADSGADNLQTHVTPTSESFPLGKLLPISPTWPFLEVKSSSAADRIKNVLGQPPDNTTLTQLSQTPLPKAHRKTRAHVDFSSSLYQGSGHSASLDLAKDPTETLVQTRPEGGREAADMSGLPRTSMLPPLPTAPSATSSAISPSQPLVGMPSLSKHPLRSDSFLFLPPPPSSSLVPDSLHSITPPKPVERPTKVPLFPQTTPADSSSGQSPVHALNPFFHKTNLFSSRNAQTFIGIPRLDFSTSLTKQYSKLSPSENPRLAASSTPGVLSSIAELDHLSLPSLAPGGLPGGTSSWSMLEEASSPVSTQPVHTAGPVRGHSAVSFPIYLRTAAASHEAWAPRFQTAESVMTSRELAPVPPTNSSANWPHLSEVPENSRKPTLSPENKPSSLVPPPPQPLTTLSQGQVVHSEAASASPQKGAGAPPSPLTVLQPSKDQAHPAPAPEAPTSQEDDRDEYLPDAATHLLSSKLPDLPPTIWTFPQQKEGKTAAIFWTNEKANGTVSLWALPTKEAPSRRAVNDSTSDFNTGRMSPLIMTALRTDLSPPGSFPSPMPTTQAPSPGVSSTKLGTLAAVTSRSELPASASKQVTALSSSTGVHDFPTMGGTRKPAATDVFQGFLSAETAPLATQSSISDLQQQTNHDVNTHTINSTHWEPHPASAALPSGTTSAANALQPQNFKEIAGQLVAADGFNLQTAALSPRPSQPPQPSEEAAVESHTDLRLAGKHAGDFDPEMVHYHASTSQHPMSQLPIRPAHPFWPTWPSLASAASLHQMLSDGTDTGPQISSDIYLSPGESGSPQFQSVLEDRSSTASPSVSTGAFSRTPSKVLRTSRRPKKWTGAATNTGSLFPGTQKTVETSVSSKGELSATVAAAATTTLFLRKSSPAPLSAALTAKGTGGGGSLAKSSLTTALAKNVTNKAAPGPKVTAGTVHTAFPFTPTYMLARTAHSLSTHTAMQGASGSVSGLLSTTHLPKKPQAMHTGLPNPTRPDTPRASTPRPLTITAALTSLTASVKATRLPSLQTGNTDAAFPAVSTAMVTTGRMASNLDCQMSHKFLVKTVFFLTQRRIQSSESLKLGVTKGLTQALRKAFHQNDVSAHVDILEYSHNVTVGYYATKGRLVYLPAVVMDVLGVYGVSNVTADLKQHAPNLQSVAVLASPWKPQPAGAFQLKTVLQFVSQSDNIQSCRFAQTMEQRLQKAFQDAERKVLGTRSNLTVQIVSTSNASQAVTLVYAVGNQSSFLNGTMASSLLSQLSAELVGFYLTYPPLTIAEPLEYPNLDTSETTRDYWVITVLQGVDNSLVGLHNQSFARVMEQRLAQLFMMSQQQGRRFKRATTLGSYTVQMVKMQRVPGPKDPAELTYYTLYNGKPLLGTAAAKILSTIDSQRMALTLHHVVLLQADPVVKNPPNNLWIIAAVLAPIAVVTIIIIIITAVLCRKNKNDFKPDTMINLPQRAKPVQGFDYAKQHLGQQGADEEVIPVTQETVVLPIPVRDTPQERDTAQDGSTIKTAKSTETRKSRSPSENGSVISNESGKPSSGRCSPQNGMTQQKVTKEESRKRNGTASDEEEGAGLFDSAGKAAADPFDTSSGSVQLIAIKPSALPVVHPASDRGPESSAALNGEVSKALKQKSDIEHYRNKLRLKAKRKGYYDFPPVDAGKGLTERKKMYEKAPKEMEHALEPDPELCAPFAESKNRQQMKNSVYRSRQSLNSPSPGETEMDLLVTRERPRRGIRNSGYDTEPEIIEETNVDRVHEPRGYGRARQMKGHSETSTLSSQPSIDEVRQQMHMLLEEAFSLASAGHAGQSRHQEAYGSTQHLPYSEVVTSAPGTMTRPRAGVQWVPTYRPEMYQYSLPRPAYRFSQLPEMVMGSPPPPVPPRTGPVAVASLRRSTSDIGSKTRMAESTGPEATQLHDSASFAQVSRGPVSVTQLDQSALNYSGNTVPAVFAIPAANRPGFTGYFIPTPPPSYRSQAWMSYAGDSELPSQWADSVPLPGYIEAYPRSRYQQSSPSRLPRQYSQPTNLHPSLEQAPVPSAAASQQSLTENEPPDTPLTNISTAALVKAIREEVAKLAKKQTDMFEFQV", "length": 2148 }, "evidence": [ { "id": "MGI:2181743", "url": "https://alliancegenome.org/gene/MGI:2181743#orthology", "database": "AGR" }, { "id": "HGNC:24836", "url": "https://alliancegenome.org/gene/HGNC:24836#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3AJM2-1", "protein_name": "UPF0606 protein KIAA1549L isoform X1", "gene_name": "kiaa1549lb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAVRVAGIWRDLRRLSSSVLRSGDWRRGCSCTGMRSAKLSSLAIFLLLLHNAQASDDEFSHEASGSFLEVASSPSSIHLLGGFFMTDRNPASVVQSDPKGSSKSRREQPAFSSFLTLLASTAQKAPEPPTKVAVRDNETHQWPLNGSLERVESSFSHPPSRLVSNHSHSESEWISELVVPAATSRVVETLHQANDSEQRNTAPSNRSSDTAVDSQQEQPAIAATTVSQPTGFTSNTVTTTSTPFTTTTKQISTTQSSAAKRHSKTHSATIRTTTTTTLLGFPKTTPRIWFASTSQSTKLDSSRSTAGPPKVAATEATLMRCNITDKMWIKTVLSIQLRRSRLDSILKQNLPRGFTQALKKALNDSMVQAKLERISSVPNVTVGYYVTNGEMVYSASVVVEALSVYGIERLMADIRQFVPLVQAVPIPAVPWRPSPAISLMLKTVLRFVGPGDDIRSCRFTQMMEQRLENAFAEAEAIVMNSHSTLAVQILSTSQSLGSPAVSLIYMVRNGSVTLNGTTASNLLSHLTAELVGYFLFYPPLITAEPLEYHNINTSVETRPFWIITVIQDVSNSSLEVQYQSFASLMEERLAELFMVAHQQGVRFKRATTVGSYTVQMVSIRRVHGTKNPAEMTYYVQQNGTPMLGTSAAKLLNTVDSQTMALTLGYFVQLQAEAVVKNPPNNLWIIAAVLAPIGVVTLIIIIITTVLCHKNKNDFKSDPISNYNPRVKTTYWRDVGYYPQPVQGFDYAKQHLGQQGGDEETLPVTQETMILPHPIRDAPLSLDKPARQDGSTSKKSLNSEIRKSRLPSEDGSVISSESVKEVSGKGSSVQKATAQQKLTKEETRKSNDHYDSSSGSLHLISIKPMAAPPTYSHPMSSDRSQDSAVFNGEVNLALKQKSDIEHYRNKLRLKAKRKGYYDFPSAEEKSSTKDLSQRHNRPPHPHSRAQEQEDDRGSTYVKHRRRPSQVSHPTHRSRQSLNSPSPGGTEMDLLVMRERPRKGIRNSGYDTEPEIIEETDVDRLGGRHYFGCGRQIKGQSETSTLSSQPSIDEVRQQMHLLLEEAFSLASAGHSTSSRHHHHHSHLQHPPLGPYGLGPVIPYSEVVTSAPGTTSQGQGGLQWVPAYRPDPYQCSLGKQAFRFTQLPEMALGSPPPPVPPRTGPPPESSLRRSSSDLGPKALCSESSVSSQHDSAPYIPNSRVPLPPAITEPVPNHSGNPMTAVYAIPATRPGYTGYFISTPPSSYHSPSWMSYPPEPEDVPPQWAESMPLPGYAEAFPHPHYPQGSPLLWHHRQITQGGPDQLPFSSTAASQQSLTESGDPISPEIPLSSLSTSALVKAIRDEVAKLAKKQADMFEFQV", "length": 1354 }, "evidence": [ { "id": "MGI:2181743", "url": "https://alliancegenome.org/gene/MGI:2181743#orthology", "database": "AGR" }, { "id": "HGNC:24836", "url": "https://alliancegenome.org/gene/HGNC:24836#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZVL6-1", "protein_name": "UPF0606 protein KIAA1549L", "gene_name": "KIAA1549L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDHTASQNAQDLIGIPHLGVSGSSTKWHSELSPTEGPHSAGSSTPGFLSPMAELSHPSPPPPALGSLLQLPDGSPSWSMLEVASGPASTQQIKAGVPGRVHNGVSLPTFKNTETATHEAEPPLFQTAESGAIEMTSRKLASATANDSANPLHLSAAPENSRGPALSAEHTSSLVPSLHITTLGQEQAILSGAVPASPSTGTADFPSILTFLQPTENHASPSPVPEMPTLPAEGSDGSPPATRDLLLSSKVPNLLSTSWTFPRWKKDSVTAILGKNEEANVTIPLQAFPRKEVLSLHTVNGFVSDFSTGSVSSPIITAPRTNPLPSGPPLPSILSIQATQTVFPSLGFSSTKPEAYAAAVDHSGLPASASKQVRASPSSMDVYDSLTIGDMKKPATTDVFWSSLSAETGSLSTESIISGLQQQTNYDLNGHTISTTSWETHLAPTAPPNGLTSAADAIKSQDFKDTAGHSVTAEGFSIQDLVLGTSIEQPVQQSDMTMVGSHIDLWPTSNNNHSRDFQTAEVAYYSPTTRHSVSHPQLQLPNQPAHPLLLTSPGPTSTGSLQEMLSDGTDTGSEISSDINSSPERNASTPFQNILGYHSAAESSISTSVFPRTSSRVLRASQHPKKWTADTVSSKVQPTAAAAVTLFLRKSSPPALSAALVAKGTSSSPLAVASGPAKSSSMTTLAKNVTNKAASGPKRTPGAVHTAFPFTPTYMYARTGHTTSTHTAMQGNMDTASGLLSTTYLPRKPQAMHTGLPNPTNLEMPRASTPRPLTVTAALTSITASVKATRLPPLRAENTDAVLPAASAAVVTTGKMASNLECQMSSKLLVKTVLFLTQRRVQISESLKFSIAKGLTQALRKAFHQNDVSAHVDILEYSHNVTVGYYATKGKLVYLPAVVIEMLGVYGVSNVTADLKQHTPHLQSVAVLASPWNPQPAGYFQLKTVLQFVSQADNIQSCKFAQTMEQRLQKAFQDAERKVLNTKSNLTIQIVSTSNASQAVTLVYVVGNQSTFLNGTVASSLLSQLSAELVGFYLTYPPLTIAEPLEYPNLDISETTRDYWVITVLQGVDNSLVGLHNQSFARVMEQRLAQLFMMSQQQGRRFKRATTLGSYTVQMVKMQRVPGPKDPAELTYYTLYNGKPLLGTAAAKILSTIDSQRMALTLHHVVLLQADPVVKNPPNNLWIIAAVLAPIAVVTVIIIIITAVLCRKNKNDFKPDTMINLPQRAKPVQGFDYAKQHLGQQGADEEVIPVTQETVVLPLPIRDAPQERDVAQDGSTIKTAKSTETRKSRSPSENGSVISNESGKPSSGRRSPQNVMAQQKVTKEEARKRNVPASDEEEGAVLFDNSSKVAAEPFDTSSGSVQLIAIKPTALPMVPPTSDRSQESSAVLNGEVNKALKQKSDIEHYRNKLRLKAKRKGYYDFPAVETSKGLTERKKMYEKAPKEMEHVLDPDSELCAPFTESKNRQQMKNSVYRSRQSLNSPSPGETEMDLLVTRERPRRGIRNSGYDTEPEIIEETNIDRVPEPRGYSRSRQVKGHSETSTLSSQPSIDEVRQQMHMLLEEAFSLASAGHAGQSRHQEAYGSAQHLPYSEVVTSAPGTMTRPRAGVQWVPTYRPEMYQYSLPRPAYRFSQLPEMVMGSPPPPVPPRTGPVAVASLRRSTSDIGSKTRMAESTGPEPAQLHDSASFTQMSRGPVSVTQLDQSALNYSGNTVPAVFAIPAANRPGFTGYFIPTPPSSYRNQAWMSYAGENELPSQWADSVPLPGYIEAYPRSRYPQSSPSRLPRQYSQPANLHPSLEQAPAPSTAASQQSLAENDPSDAPLTNISTAALVKAIREEVAKLAKKQTDMFEFQV", "length": 1849 }, "evidence": [ { "id": "MGI:2181743", "url": "https://alliancegenome.org/gene/MGI:2181743#orthology", "database": "AGR" }, { "id": "HGNC:24836", "url": "https://alliancegenome.org/gene/HGNC:24836#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-55", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-55#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1232, "end_pos": 1234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1306, "end_pos": 1308, "annotation": "n_glycosylation_sequon" }, { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 221, "end_pos": 223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 370, "end_pos": 372, "annotation": "n_glycosylation_sequon" }, { "start_pos": 397, "end_pos": 399, "annotation": "n_glycosylation_sequon" }, { "start_pos": 411, "end_pos": 413, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" }, { "start_pos": 558, "end_pos": 560, "annotation": "n_glycosylation_sequon" }, { "start_pos": 564, "end_pos": 566, "annotation": "n_glycosylation_sequon" }, { "start_pos": 601, "end_pos": 603, "annotation": "n_glycosylation_sequon" }, { "start_pos": 687, "end_pos": 689, "annotation": "n_glycosylation_sequon" }, { "start_pos": 758, "end_pos": 760, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" }, { "start_pos": 915, "end_pos": 917, "annotation": "n_glycosylation_sequon" }, { "start_pos": 986, "end_pos": 988, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 270, 430, 1119 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1232, "end_pos": 1234 }, { "start_pos": 1306, "end_pos": 1308 }, { "start_pos": 144, "end_pos": 146 }, { "start_pos": 210, "end_pos": 212 }, { "start_pos": 221, "end_pos": 223 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 370, "end_pos": 372 }, { "start_pos": 397, "end_pos": 399 }, { "start_pos": 411, "end_pos": 413 }, { "start_pos": 428, "end_pos": 430 }, { "start_pos": 558, "end_pos": 560 }, { "start_pos": 564, "end_pos": 566 }, { "start_pos": 601, "end_pos": 603 }, { "start_pos": 687, "end_pos": 689 }, { "start_pos": 758, "end_pos": 760 }, { "start_pos": 88, "end_pos": 90 }, { "start_pos": 915, "end_pos": 917 }, { "start_pos": 986, "end_pos": 988 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 3 }, { "field": "total_sites", "count": 3 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 3 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 3 }, { "field": "exact_o_linked_sites", "count": 3 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1Q5S6-1", "uniprot_ac": "F1Q5S6", "uniprot_id": "F1Q5S6_DANRE", "mass": { "chemical_mass": 66807.0, "monoisotopic_mass": 66807.0 }, "refseq": { "ac": "NP_001189455", "name": "uncharacterized aarF domain-containing protein kinase 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189455" }, "gene_names": [ { "name": "adck5", "type": "recommended", "evidence": [ { "id": "F1Q5S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6" } ] }, { "name": "adck5", "type": "synonym", "evidence": [ { "id": "NP_001189455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189455" } ] }, { "name": "si:ch211-169c1.2", "type": "synonym", "evidence": [ { "id": "NP_001189455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189455" }, { "id": "F1Q5S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6" } ] } ], "protein_names": [ { "name": "Uncharacterized aarF domain-containing protein kinase 5", "type": "synonym", "evidence": [ { "id": "F1Q5S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized aarF domain-containing protein kinase 5", "type": "synonym", "evidence": [ { "id": "NP_001189455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189455" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01007382.1, SRR32588715.470262.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505389, SAMEA4476747 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000019.1. On Feb 5, 2011 this sequence version replaced XP_001341554.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001189455", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189455" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q5S6", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "adck5", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-149", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-149", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000075405", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000075405", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13969", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13969", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100001584", "url": "https://www.ncbi.nlm.nih.gov/gene/100001584", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004147", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004147", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051130", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051130", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100001584", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001584", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DVMTTMV", "url": "https://omabrowser.org/oma/group/DVMTTMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3ASF6", "url": "https://www.orthodb.org/?gene=A0A8M3ASF6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1Q5S6", "url": "https://www.orthodb.org/?gene=F1Q5S6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR43173", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43173", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR43173:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR43173:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03109", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03109", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001189455", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189455", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3ASF6", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ASF6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3ASF6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ASF6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q5S6", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q5S6-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-149", "url": "https://zfin.org/ZDB-GENE-081104-149", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAAETFRSLRLCRHHMSLLRKCPRLIAPQVFHQKFSSNRVVKGHRLFRKLLLGVSVGVPLVVGVQYVVSEPRERRKMKMLTEGIGRFCRSLYVGLMISADYWWTSNIALRGMDESSPEFLKQMSACHQRAASNMVDGAIQNGGLYIKLGQGLCAFNHLLPPEYIQTLHVLEDKALNRRYKEVDALFQEDFNMTPDKMFRTFDYEPVAAASLAQVHKAELHDGTPVAVKVQYIDLRDRFDGDIRTLEILLDVIKFMHPSFGFRWVLQDLKGTLAQELDFENEGRNSERCAEELKHFKFVVVPKVFWDVTSKRVLTAEYCDGCKINNVEEIQRQGLSLKDTADKLIRIFAEQIFYTGFIHADPHPGNVLVRRGPDKKAELVLLDHGLYEHLSKSDRAALCQLWRAIILRDDAGMKTYANQLGVKEYFLFSEMLLQRPINMWDLGLGNILTGEETSYMRDMAINRFDKIMQVLKSMPRPMLLVFRNINTVRCINITLGAPVDRYFIMAKCAVRGHGRAQAEDIRLFSRLSVFRWVCSFWESLKFEFALRSEMALMSVTRSLLKLLAFCNMVTLDQDVFQYLK", "length": 579, "header": "tr|F1Q5S6-1|F1Q5S6_DANRE Isoform 1 of Uncharacterized aarF domain-containing protein kinase 5 OS=Danio rerio OX=7955 GN=adck5 PE=3 SV=1 CANONICAL=F1Q5S6-1" }, "isoforms": [ { "isoform_ac": "A0A8M3ASF6-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6/entry#A0A8M3ASF6-1", "sequence": { "sequence": "MSPEFLKQMSACHQRAASNMVDGAIQNGGLYIKLGQGLCAFNHLLPPEYIQTLHVLEDKALNRRYKEVDALFQEDFNMTPDKMFRTFDYEPVAAASLAQVHKAELHDGTPVAVKVQYIDLRDRFDGDIRTLEILLDVIKFMHPSFGFRWVLQDLKGTLAQELDFENEGRNSERCAEELKHFKFVVVPKVFWDVTSKRVLTAEYCDGCKINNVEEIQRQGLSLKDTADKLIRIFAEQIFYTGFIHADPHPGNVLVRRGPDKKAELVLLDHGLYEHLSKSDRAALCQLWRAIILRDDAGMKTYANQLGVKEYFLFSEMLLQRPINMWDLGLGNILTGEETSYMRDMAINRFDKIMQVLKSMPRPMLLVFRNINTVRCINITLGAPVDRYFIMAKCAVRGHGRAQAEDIRLFSRLSVFRWVCSFWESLKFEFALRSEMALMSVTRSLLKLLAFCNMVTLDQDVFQYLK", "length": 465, "header": "tr|A0A8M3ASF6-1|F1Q5S6_DANRE Computationally mapped isoform of Uncharacterized aarF domain-containing protein kinase 5 OS=Danio rerio OX=7955 GN=adck5 PE=3 SV=1 CANONICAL=F1Q5S6-1" }, "locus": {} }, { "isoform_ac": "F1Q5S6-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6/entry#F1Q5S6-1", "sequence": { "sequence": "MAAETFRSLRLCRHHMSLLRKCPRLIAPQVFHQKFSSNRVVKGHRLFRKLLLGVSVGVPLVVGVQYVVSEPRERRKMKMLTEGIGRFCRSLYVGLMISADYWWTSNIALRGMDESSPEFLKQMSACHQRAASNMVDGAIQNGGLYIKLGQGLCAFNHLLPPEYIQTLHVLEDKALNRRYKEVDALFQEDFNMTPDKMFRTFDYEPVAAASLAQVHKAELHDGTPVAVKVQYIDLRDRFDGDIRTLEILLDVIKFMHPSFGFRWVLQDLKGTLAQELDFENEGRNSERCAEELKHFKFVVVPKVFWDVTSKRVLTAEYCDGCKINNVEEIQRQGLSLKDTADKLIRIFAEQIFYTGFIHADPHPGNVLVRRGPDKKAELVLLDHGLYEHLSKSDRAALCQLWRAIILRDDAGMKTYANQLGVKEYFLFSEMLLQRPINMWDLGLGNILTGEETSYMRDMAINRFDKIMQVLKSMPRPMLLVFRNINTVRCINITLGAPVDRYFIMAKCAVRGHGRAQAEDIRLFSRLSVFRWVCSFWESLKFEFALRSEMALMSVTRSLLKLLAFCNMVTLDQDVFQYLK", "length": 579, "header": "tr|F1Q5S6-1|F1Q5S6_DANRE Isoform 1 of Uncharacterized aarF domain-containing protein kinase 5 OS=Danio rerio OX=7955 GN=adck5 PE=3 SV=1 CANONICAL=F1Q5S6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "F1Q5S6", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "F1Q5S6", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "High-Resolution Proteomic Profiling Shows Sexual Dimorphism in Zebrafish Heart-Associated Proteins.", "journal": "J. Proteome Res.", "date": "2021", "authors": "Niksirat Hamid, Siino Valentina, Steinbach Christoph, Levander Fredrik", "evidence": [ { "database": "UniProtKB", "id": "F1Q5S6", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6" } ], "reference": [ { "type": "PubMed", "id": "34185526", "url": "https://glygen.org/publication/PubMed/34185526" } ] } ], "pathway": [ { "id": "dre:100001584", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100001584", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2M8N0-1", "protein_name": "Uncharacterized aarF domain-containing protein kinase 5 isoform X1", "gene_name": "Adck5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MWRPMRLCHFHSALLQNRQKPWPCPAIFFRRNFKSPMARTSRTRLLWRRTLSATVVGVPLLLGARYFTAEAQEKRRLRLAVDGIGRFGRSLKVGLLISLDYWWCTNVILRGVEENSPGYVKVMSACHQRAADALVAGAIRNGGLYVKLGQGLCSFNHLLPPEYIQTLRVLEDKALTRGFREVDELFLEDFQALPNELFQEFDYEPMAAASLAQVHRAKLHDGTAVAVKVQYIDLRDRFDGDVHTLELLLQLVELMHPSFGFSWVLQDLKGTLAQELDFENEGRNSERCAQELKHFHYVVVPRVHWDKSSKRVLTADFCEGCKVNDTEAIKRQGLAVQDVAKKLIQTFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELVLLDHGLYQFLDEKDRSSLCQLWRAIILRDSAAMKTHAAELGVQDYMLFSEVLMQRPVRLGQLWGSHLLSREETVYMQDMAREHFEGIMEVLKALPRPMLLVLRNINTVRAINSTLGTPVDRYFLMAKSAVWGWSRLVGAAYHGIYSSSLLRHIKVIWETFKFEVALRLEILAMRLTALLLRVLARLGFAPKAKDVSQYLEM", "length": 580 }, "evidence": [ { "id": "F1Q5S6", "url": "https://omabrowser.org/oma/group/F1Q5S6/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "F1RSN7-1", "protein_name": "AarF domain containing kinase 5", "gene_name": "ADCK5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWRPSQLCHVHSALLQGRLKPWPSPATFFRRHLRVPPAKWSLRPQPLWRKALSVTAVGAPLLLGVRYFTAEPQERRRMRLVVDGVGRFGRSLRVGLQISLDYWWCTHVVLRGVEENSPRYLEVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYIRTLRVLEDRALTRGIQEVDELFLEDFQAPPRELFRDFDYQPIAAASLAQVHRARLHDGTEVAVKVQYIDLRDRFEGDIHTLELLLQLVELMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELRHFRYVVVPRVHWDTSSKRVLTADFYEGCKVNDVEAIKTMGLAVRDIAEKLIQAFAEQIFYTGFIHSDPHPGNVLVRRGPDGKAQLVLLDHGLYQFLDAKDRSALCQLWRAIILRDEAAMKTHAAALGVQDYLLFSEVLMQRPVRLGQLWRSNLLSREEAAYMRDMAREHFEEVMAVLKALPRPMLLVLRNVNTVRAINTALGAPVDRYFLMAKSAVRGWSRLAGTGRQDAYGARLLRHVRVVWETFKFEVALRLETLSMQLTALLVRVLVHLGLLPEAQGLYEYLET", "length": 581 }, "evidence": [ { "id": "F1Q5S6", "url": "https://omabrowser.org/oma/group/F1Q5S6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3V9I7-1", "protein_name": "AarF domain containing kinase 5", "gene_name": "Adck5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPQATSRGRCGVAEVVTSRLGGVALPLYPGLCGECGPVRKRIAYSFAGSAEQWGRLRRNREESTAGDMWRPMRLCHFHSTLLQSRQKPWPCPAIFFRRNFKSPLARTSRTRLLWRRTFSATVVGTPFLFGAHYFMAESSERRKLRLAVDGIGRFGRSVKIGFFISLDYWWCTNVVLRGVEENSPKYVEIMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPTEYIQTLRVLEDKALTRGFREVDELFLEDFQALPSELFQEFDYEPMAAASLAQVHRAKLQDGTAVAVKVQYIDLRDRFDGDVHTLELLLRLVELMHPSFGFSWVLQDLKGTLAQELDFENEGRNSERCAQELKHFHHVVIPRVYWDKSSKRVLTADFCDGCKVNDMEGIKSQGLAVQDVATKLIQTFAEQIFHTGFIHSDPHPGNVLVRKGPDGKAELVLLDHGLYQFLDEKDRSSLCQLWRAIILRDDAAMKTHAAALGVQDYMLFSEVLMQRPVRLGQLWGSHLISREEAAYMQDMAREHFDGIMEVLKSLPRPMLLVLRNINTVRAINSSLGTPVDRYFLMAKSAVWGWSRLVGAAYQGIYSSRLLRHIKVIWEALKFEVILRLEILAMRFTALMLRVMVRLGFAPKAEAEEVYQYLEM", "length": 649 }, "evidence": [ { "id": "MGI:2679274", "url": "https://alliancegenome.org/gene/MGI:2679274#orthology", "database": "AGR" }, { "id": "HGNC:21738", "url": "https://alliancegenome.org/gene/HGNC:21738#orthology", "database": "AGR" }, { "id": "F1Q5S6", "url": "https://omabrowser.org/oma/group/F1Q5S6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q06567-1", "protein_name": "ABC1 family protein MCP2", "gene_name": "MCP2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MMTKAFFNKLPFEVFRRYVRTGKSIPQRSPRTRKSLLVGGTIASAVVLYNFNDTFHDSVKHTALTTKRIAVVTQATTRCFYHYKRALNKSYENKKEREVALNKCHKMCALITLHALRSNGGIYIKLGQHIGAMTYLLPKEWTDTMIPLQDHCPESTYEEIDELFKEDLGTSIEDMFLEFNKTPIGVASLAQVHVAKLKNSDGKGSSVAVKCQHPSLKEFIPLDVMLTRTVFELLDVFFPDYPLTWLGDELQSSIYVELNFTKEAENAEKTRHYFSKFKKQTALKIPKVIESHKRILIMEYVGGKRLDDLEYIDSHGISRSEVSSCLSHIFNNMIFTPNVGIHCDPHGGNLAIRSVKPAKDNGYHNFEIVLFDHGLYRYPSTRTRRLYAKFWLSLLFDKDQTKMKKYAKGFANITDEQFPLLAAAITGRSIDAALNYDISTSRTQEEMDVMANGILEGTLLSDLMSILSRIPRVVLLILKTNDLTRHLDECLQNPLGPERTFLIMTQYCAKTVYDEKVERINSEYARWSIKWMWENLTNWIVYERRINQLYFYDFVLWWKKFIPKTWLSS", "length": 569 }, "evidence": [ { "id": "MGI:2679274", "url": "https://alliancegenome.org/gene/MGI:2679274#orthology", "database": "AGR" }, { "id": "HGNC:21738", "url": "https://alliancegenome.org/gene/HGNC:21738#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3MIX3-1", "protein_name": "Uncharacterized aarF domain-containing protein kinase 5", "gene_name": "ADCK5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWRPVQLCHFHSALLHSRQKPWPSPAVFFRRNVRGLPPRFSSPTPLWRKVLSTAVVGAPLLLGARYVMAEAREKRRMRLVVDGMGRFGRSLKVGLQISLDYWWCTNVVLRGVEENSPGYLEVMSACHQRAADALVAGAISNGGLYVKLGQGLCSFNHLLPPEYTRTLRVLEDRALKRGFQEVDELFLEDFQALPHELFQEFDYQPIAAASLAQVHRAKLHDGTSVAVKVQYIDLRDRFDGDIHTLELLLRLVEVMHPSFGFSWVLQDLKGTLAQELDFENEGRNAERCARELAHFPYVVVPRVHWDKSSKRVLTADFCAGCKVNDVEAIRSQGLAVHDIAEKLIKAFAEQIFYTGFIHSDPHPGNVLVRKGPDGKAELVLLDHGLYQFLEEKDRAALCQLWRAIILRDDAAMRAHAAALGVQDYLLFAEMLMQRPVRLGQLWGSHLLSREEAAYMVDMARERFEAVMAVLRELPRPMLLVLRNINTVRAINVALGAPVDRYFLMAKRAVRGWSRLAGATYRGVYGTSLLRHAKVVWEMLKFEVALRLETLAMRLTALLARALVHLSLVPPAEELYQYLET", "length": 580 }, "evidence": [ { "id": "MGI:2679274", "url": "https://alliancegenome.org/gene/MGI:2679274#orthology", "database": "AGR" }, { "id": "HGNC:21738", "url": "https://alliancegenome.org/gene/HGNC:21738#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-149", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-149#orthology", "database": "AGR" }, { "id": "F1Q5S6", "url": "https://omabrowser.org/oma/group/F1Q5S6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80V03-1", "protein_name": "Uncharacterized aarF domain-containing protein kinase 5", "gene_name": "Adck5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWRPMRLCHFHSTLLQSRQKPWPCPAIFFRRNFKSPPARTSRARLLWRRALSATVVGTPFLLGAYYFMAEASERRKLRLAVDGIGRFGRSVKIGLFISTDYWWCTNVVLRGVEENSPKYVEIMSACHQRAADALVAGAIRNGGLYVKLGQGLCSFNHLLPTEYIQTLRVLEDKALTRGFREVDELFLEDFQALPNELFQEFDYEPMAAASLAQVHRAKLHDGTDVAVKVQYIDLRDRFDGDVQTLELLLRLVELMHPSFGFSWVLQDLKGTLVQELDFENEGRNAERCAQELKHFHYVVIPRVHWDRSSKRVLTADFCNGCKVNDMEGIKSQGLAVQDVAKKLIQTFAEQIFHTGFIHSDPHPGNVLVRKGPDGKAELVLLDHGLYQFLDEKDRSSLCQLWRAIILRDNAAMKKHAAALGVQDYMLFSEVLMQRPVRLGQLWGSHLISREEAAYMQDMAREHFDGIMEVLKALPRPMLLVLRNINTVRAINSNLGTPVDRYFLMAKSAVWGWSRLVGAAYQGIYGSSLLRHIKVLWEALKFEMALRLEILAMRLTALMLRVLVRLGFAPKAEAEEVYQYLEM", "length": 582 }, "evidence": [ { "id": "MGI:2679274", "url": "https://alliancegenome.org/gene/MGI:2679274#orthology", "database": "AGR" }, { "id": "HGNC:21738", "url": "https://alliancegenome.org/gene/HGNC:21738#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-149", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-149#orthology", "database": "AGR" }, { "id": "F1Q5S6", "url": "https://omabrowser.org/oma/group/F1Q5S6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VTG5-1", "protein_name": "AarF domain containing kinase 5, isoform A", "gene_name": "Adck5", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRPLQRVRQLLSLGTRIRGKRALNGLREANVQKGGRPVLRFSLLAAGAGGLAYDGIVNDFTYCGASVRFVRSLKTAGLIAADYLRLDENDPEYETKVKLLHKKSAERLLETCLLNGGLYIKVGQGFAAINDILPVEYTSTLSLLQDRCLPTTQADVQKVFRKDFGQLPEEIYQEFDYQPVAAASLAQVFKARLPSGEQVAVKVQYNDLQKRFISDLGTIIFLQDIVEFFFKDYNFGWILNDLRKNLVLELNFLQEGQNAERCAKDMEKFSYVHVPKVHWSYTKTRVLTLEWMDGCKISDLKTIEKEKLSLKDIDVKLFEAFAEQIFYTGFVHADPHPGNIFVRKNRKNGRADIILLDHGLYEELPQNVRGPLCEFWEATVLRQENRMQAAAEKIGIGDYMRFAEVLFQQPIRNRGGGIRGKLTQEDIDHMQEIARNNFEHIMGTLKEMPRSMLFVVRNLNTVRAISHQHGDVVNRPRVMARYAQKCLYMQHNRRSPVQYIRWLSGRIYFEYCLFLSAFKLYLLDWYFNILYLVGRAPASARTVMKDIMQPPEPNVLK", "length": 557 }, "evidence": [ { "id": "MGI:2679274", "url": "https://alliancegenome.org/gene/MGI:2679274#orthology", "database": "AGR" }, { "id": "HGNC:21738", "url": "https://alliancegenome.org/gene/HGNC:21738#orthology", "database": "AGR" }, { "id": "F1Q5S6", "url": "https://omabrowser.org/oma/group/F1Q5S6/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "F1Q5S6", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 491, "end_pos": 493, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1Q5S6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5S6" }, { "id": "PF03109", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03109" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ABC1 atypical kinase-like", "eco_id": "ECO_0000259", "start_pos": 170, "end_pos": 415, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 }, { "start_pos": 491, "end_pos": 493 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7FCG5-1", "uniprot_ac": "E7FCG5", "uniprot_id": "E7FCG5_DANRE", "mass": { "chemical_mass": 133093.0, "monoisotopic_mass": 133093.0 }, "refseq": { "ac": "XP_005166160", "name": "arginine-glutamic acid dipeptide repeats protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166160" }, "gene_names": [ { "name": "rereb", "type": "recommended", "evidence": [ { "id": "E7FCG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCG5" } ] }, { "name": "rereb", "type": "synonym", "evidence": [ { "id": "XP_005166160", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166160" } ] } ], "protein_names": [ { "name": "Arginine-glutamic acid dipeptide repeats protein", "type": "recommended", "evidence": [ { "id": "E7FCG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCG5/entry#names_and_taxonomy" } ] }, { "name": "arginine-glutamic acid dipeptide repeats protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005166160", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166160" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005166160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166160" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FCG5", "url": "https://www.uniprot.org/uniprotkb/E7FCG5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rereb", "url": "https://www.uniprot.org/uniprotkb/E7FCG5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070212-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070212-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000075670", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000075670", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00202", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00202", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd11661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd11661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "799473", "url": "https://www.ncbi.nlm.nih.gov/gene/799473", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000679", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000679", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000949", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000949", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002951", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002951", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:799473", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799473", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YPHSLES", "url": "https://omabrowser.org/oma/group/YPHSLES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3ATK3", "url": "https://www.orthodb.org/?gene=A0A8M3ATK3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FCG5", "url": "https://www.orthodb.org/?gene=E7FCG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13859", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13859", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13859:SF12", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13859:SF12", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00249", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00249", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00320", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00320", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01448", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01448", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF03154", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03154", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005166160", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166160", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3ATK3", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ATK3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3ATK3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3ATK3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FCG5", "url": "https://www.uniprot.org/uniprotkb/E7FCG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FCG5-1", "url": "https://www.uniprot.org/uniprotkb/E7FCG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070212-3", "url": "https://zfin.org/ZDB-GENE-070212-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDDLFSPRRQLNSTQGEIRVGPSHQAKLPELQPPPAHGTESVTENEDLVWAPGVNDCDLLMYLRAARSMAAFAGMCDGGSTEDGCLAASRDDTTLNALNTLHESQYDAAKALQCLVKKPVPKLIEKSWSEDEVKRFIKGLRQYGKNFFKIRKDLLPSKKTGELITFYYYWKKTPEAVAARPHRQQRRQPVSRKVKTRNATAAANATSRTSSMELSSASEDDLDSEDSEQGGKRQACSHCLSTNSKDWHHGGRDNVLLCSSCHTHFSKHRRLPPVPKPADPPYLFKPVKEEEEESRHGMKTRRSRVPPHMSSLRSGRNRPTGSPERGLSPPSEDVRPNGQSSRASSTTMTTRASSSDMKNGVAGKTNKKMKVEASVVKGVKRQRESAAPDADEPERKNMKRPKNQEGPDSPSECEGEGESSDSRSANEDGSSDTKDIDQDNRSSSPSLASPLQANESDSDSPAPPPASGPITQAQPQQPAAASTTHTPSESPPSPQPTLPTFSSAPSPGAATTTVTSKAPSAETTLDVPSPSPFRSGPKAPEAPTSYSNSSSQQVQCPGQGQSLPVPAHYQHNSGQLQNPSSGANQPQGFTSRPLHLQRESPFPPLPATATSQIKPPPTTPIPPSHKQPPHLSAPPPHFLQIHPNLPPPPALKPLASLPSQHLPSSQPPPLHVIPQNNPAPPSVLTQTQSQQVKSHSSAAPQVAASSHPPLPPNRPSPESTASYPLYTSPIPVPAHQPSTSSSASTPVGQAIIKEEPVDEEEECDSPPPPRRSPSPAPTVVDIPSHASQSARFIKHLNRGYNSCSRTDLYFTPLTSSKLAKKREEAAERSRREAELSARQGRERERERERERERERERERERERDSDKASRASSSSHDGRISEHLLAAHVQPGRPSFEPPPPTTVAAVPPYLGPDTPALRTLSEYARPHVMSPTNRNHPFFMPLGPGEHLLAYHMPGLYAADPALRERELRELREREIRERMKPGFEVKPPELENPLHPSANPMEHFARHGALPLAHVAGPHHFAQFHPAMERNVAAPPRPEISYAERLTAERLHAERMASVAAGDPVARLQMLNVTPHHHQHSHIHSHLHLHQQDPLNQGQGPHPLVDPLAAGPPLARFPYPPGAITNPLLSELPHEHEMLRHPLFGAPFPRELPGPLAPMSAAHQLQAMQAQSAELQRLALEQQWLHGHAHLHSAPLPSQEDYYSRLKKEGDKQS", "length": 1216, "header": "tr|E7FCG5-1|E7FCG5_DANRE Isoform 1 of Arginine-glutamic acid dipeptide repeats protein OS=Danio rerio OX=7955 GN=rereb PE=4 SV=1 CANONICAL=E7FCG5-1" }, "isoforms": [ { "isoform_ac": "A0A8M3ATK3-1", "url": "https://www.uniprot.org/uniprotkb/E7FCG5/entry#A0A8M3ATK3-1", "sequence": { "sequence": "MDDLFSPRRQLNSTQGEIRVGPSHQAKLPELQPPPAHGTESVTENEDLVWAPGVNDCDLLMYLRAARSMAAFAGMCDGGSTEDGCLAASRDDTTLNALNTLHESQYDAAKALQCLVKKPVPKLIEKSWSEDEVKRFIKGLRQYGKNFFKIRKDLLPSKKTGELITFYYYWKKTPEAVAARPHRQQRRQPVSRKVKTRNATAAANATSRTSSMELSSASEDDLDSEDSEQGGKRQACSHCLSTNSKDWHHGGRDNVLLCSSCHTHFSKHRRLPPVPKPADPPYLFKPVKEEEEESRHGMKTRRSRVPPHMSSLRSGRNRPTGSPERGLSPPSEDVRPNGQSSRASSTTMTTRASSSDMKNGVAGKTNKKMKVEASVVKGVKRQRESAAPDADEPERKNMKRPKNQEGPDSPSECEGEGESSDSRSANEDGSSDTKDIDQDNRSSSPSLASPLQANESDSDSPAPPPASGPITQAQPQQPAAASTTHTPSESPPSPQPTLPTFSSAPSPGAATTTVTSKAPSAETTLDVPSPSPFRSGPKAPEAPTSYSNSSSQQVQCPGQGQSLPVPAHYQHNSGQLQNPSSGANQPQGFTSRPLHLQRESPFPPLPATATSQIKPPPTTPIPPSHKQPPHLSAPPPHFLQIHPNLPPPPALKPLASLPSQHLPSSQPPPLHVIPQNNPAPPSVLTQTQSQQVKSHSSAAPQVAASSHPPLPPNRPSPESTASYPLYTSPIPVPAHQPSTSSSASTPVGQAIIKEEPVDEEEECDSPPPPRRSPSPAPTVVDIPSHASQSARFIKHLNRGYNSCSRTDLYFTPLTSSKLAKKREEAAERSRREAELSARQGRERERERERERERERERERERERDSDKASRASSSSHDGRISEHLLAAHVQPGRPSFEPPPPTTVAAVPPYLGPDTPALRTLSEYARPHVMSPTNRNHPFFMPLGPGEHLLAYHMPGLYAADPALRERELRELREREIRERMKPGFEVKPPELENPLHPSANPMEHFARHGALPLAHVAGPHHFAQFHPAMERNVAAPPRPEISYAERLTAERLHAERMASVAAGDPVARLQMLNVTPHHHQHSHIHSHLHLHQQDPLNQGQGPHPLVDPLAAGPPLARFPYPPGAITNPLLRAPFPRELPGPLAPMSAAHQLQAMQAQSAELQRLALEQQWLHGHAHLHSAPLPSQEDYYSRLKKEGDKQS", "length": 1201, "header": "tr|A0A8M3ATK3-1|E7FCG5_DANRE Computationally mapped isoform of Arginine-glutamic acid dipeptide repeats protein OS=Danio rerio OX=7955 GN=rereb PE=4 SV=1 CANONICAL=E7FCG5-1" }, "locus": {} }, { "isoform_ac": "E7FCG5-1", "url": "https://www.uniprot.org/uniprotkb/E7FCG5/entry#E7FCG5-1", "sequence": { "sequence": "MDDLFSPRRQLNSTQGEIRVGPSHQAKLPELQPPPAHGTESVTENEDLVWAPGVNDCDLLMYLRAARSMAAFAGMCDGGSTEDGCLAASRDDTTLNALNTLHESQYDAAKALQCLVKKPVPKLIEKSWSEDEVKRFIKGLRQYGKNFFKIRKDLLPSKKTGELITFYYYWKKTPEAVAARPHRQQRRQPVSRKVKTRNATAAANATSRTSSMELSSASEDDLDSEDSEQGGKRQACSHCLSTNSKDWHHGGRDNVLLCSSCHTHFSKHRRLPPVPKPADPPYLFKPVKEEEEESRHGMKTRRSRVPPHMSSLRSGRNRPTGSPERGLSPPSEDVRPNGQSSRASSTTMTTRASSSDMKNGVAGKTNKKMKVEASVVKGVKRQRESAAPDADEPERKNMKRPKNQEGPDSPSECEGEGESSDSRSANEDGSSDTKDIDQDNRSSSPSLASPLQANESDSDSPAPPPASGPITQAQPQQPAAASTTHTPSESPPSPQPTLPTFSSAPSPGAATTTVTSKAPSAETTLDVPSPSPFRSGPKAPEAPTSYSNSSSQQVQCPGQGQSLPVPAHYQHNSGQLQNPSSGANQPQGFTSRPLHLQRESPFPPLPATATSQIKPPPTTPIPPSHKQPPHLSAPPPHFLQIHPNLPPPPALKPLASLPSQHLPSSQPPPLHVIPQNNPAPPSVLTQTQSQQVKSHSSAAPQVAASSHPPLPPNRPSPESTASYPLYTSPIPVPAHQPSTSSSASTPVGQAIIKEEPVDEEEECDSPPPPRRSPSPAPTVVDIPSHASQSARFIKHLNRGYNSCSRTDLYFTPLTSSKLAKKREEAAERSRREAELSARQGRERERERERERERERERERERERDSDKASRASSSSHDGRISEHLLAAHVQPGRPSFEPPPPTTVAAVPPYLGPDTPALRTLSEYARPHVMSPTNRNHPFFMPLGPGEHLLAYHMPGLYAADPALRERELRELREREIRERMKPGFEVKPPELENPLHPSANPMEHFARHGALPLAHVAGPHHFAQFHPAMERNVAAPPRPEISYAERLTAERLHAERMASVAAGDPVARLQMLNVTPHHHQHSHIHSHLHLHQQDPLNQGQGPHPLVDPLAAGPPLARFPYPPGAITNPLLSELPHEHEMLRHPLFGAPFPRELPGPLAPMSAAHQLQAMQAQSAELQRLALEQQWLHGHAHLHSAPLPSQEDYYSRLKKEGDKQS", "length": 1216, "header": "tr|E7FCG5-1|E7FCG5_DANRE Isoform 1 of Arginine-glutamic acid dipeptide repeats protein OS=Danio rerio OX=7955 GN=rereb PE=4 SV=1 CANONICAL=E7FCG5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:799473", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799473", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2B939-1", "protein_name": "Arginine-glutamic acid dipeptide repeats protein", "gene_name": "rerea", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTADKEKDKERERDRDRDRDREKRDKTRESESSRPRRSCTLEGGAKNYAESEHSEDDDNETPGAATAEEATKKSKKKLPKKKSRYERTENGEITSFITEDDIVYRPGDCVYIESRRPNTPYFICSIQDFKLSKRDHLLMNVKWYYRQSEVPDSVYQHLVQDRNNENDSGRELVITDPVVKSRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARIDSFFYILGYNPETRRLNSTQGEIRVGPSHQAKLPELQPFPSPGGQTVTENEELVWMPGVNDCDLLMYLRAARSMAAFAGMCDGGSTEDGCLAASRDDTTLNALNTLHESSYDAGKALQRLVKKPVPKLIEKCWSEDEVKRFIKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKKTPEAASCRAHRRHRRQPVFRRIKTRTASTPVNTPSRPPSSEFLDLSSASEDDFDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRNRGSMSTLRSGRKKQTASPDGRASPTNEDLRSSGRTSPSAASTSSTDSKTDSMKKPSKKTKEEAPSPMKSAKRQREKGASDTEESERASAKKSKTQEISVPNSPSECEGEGEGESSDGRSVNDEGSSDPKDIDQDNRSSSPSIPSPRDNESDSDSSAQQQILQGQHPPVIQCQTGTLPPAPPPAAAASTTPTSGAPSLSSQPSPSIPPTSMPPQQIPPAGPLSLIQSGVQRLPSPHSPLQGMPQPPPPSQTCPQALQPPLHGPMPPMGHPLQAGPSHMPHPHALPTQPFPMAQSQVPPSPLSGQAQAASLSQQQRPHTPPSQSQSSSQSGSQPPREQPLPPAPLPMPHIKPPPTTPIPQMPNAQSHKHPSHPPFPQMPSNLPPPPALKPLSSLSNHHPPSAHPPPLQLMSQSQQLQPPPVQPPVLTQSQTLPATGSQAPPPAPPLPSSSSASHSAPSQPPFPPHSFMPGSSPVLSPSTVPTSVSSSMTTLQQPPPSISMPLPASVSAPCPGPSTVPPVQIKEEPLDETEEPESPPPPQRSPSPPPTIVNTPSHASQSARFYKHLDRGYNTCARTDFYFTPLASSKLAKKREEALEKAKREAEQKAREEKEKEREREKEREREREREKEAERAAKASSSSHESRMGEPPMAGSAHMRTSFDPPPTTIATVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFFVSLNPTDPLLAYHLPGLYNADPSMRERELREREIREREIRERELRMERMKPGFEVKPPELDSLHPSANPMEHFARHGPIGLPPMAGPHPFASFHPGLNPLERERLALAGPQLRPEMTYPERLAERLHVERLANDPMARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGGGECLVCPPGSGAHPLVDPLAGGPHLARFPYPPGAIPNPLLGQPPHEHEMLRHPVFGTPYPRDLPAGLPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHHHMHGGPLPGQEDYYSRLKKESDKQL", "length": 1531 }, "evidence": [ { "id": "HGNC:9965", "url": "https://alliancegenome.org/gene/HGNC:9965#orthology", "database": "AGR" }, { "id": "MGI:2683486", "url": "https://alliancegenome.org/gene/MGI:2683486#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "M9PHT1-1", "protein_name": "Grunge, isoform J", "gene_name": "Gug", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAASTQGEIRVGPGHQVNDVYAKLPDYNPISSFPIDKETDERELEESRWSPGVVADGDLLMFLRAARSMAAFQGMCDGGLEDGCLAASRDDTTINALDVLHDSGYDPGKALQALVKCPVSKGIDKKWTEDETKKFIKGLRQFGKNFFRIHKDLLPHKDTPELVEFYYLWKKTPGANNNRPHRRRRQSALRRNRVTRANNSNSNTPPKKEDTPEPQTATTATAAATAASETASRSSPAVSKEENSSLTEDDASECDSDSSLTHKRDESPSRMRTRNKQQNNNSSTSSGNNTAGNGGGNATSISSGSTGGGAAGGNSSSKDQSANAVANGKRPKRGSETPDVSGGASVDSPKTPTKAVAESSANKRKGGKQDTPNKKKRTEQESNEPSAHEENAIKEKRKRPDSPVESMNSDSRPDSVLDDGESNTTDTTTAEQQSTKDSKETVSCKEEREMVTNDLEAKAEEKAIKAEALAEDSKDSAIKNMDEETNIQAPSSADTSLVDGPNPNALPSPVAAPITMKVPTIATVEALNASVDRKEAIEKMESCDSDPEMLKKLATIKQEVSPQQQQHMQQQSQQQMQQQLAPVGIPQPPSCPPSESVYIKKEPMEDSMDATCNQNSNEPQDLKVKIEIKNEDALKHSAGGLPPSGPCAPPSALHPLSGAPVESGQEPLHLQHMPHGQVTTQPPPGYLIDGQLKYGPSGQGVPPQPPQLHSDAAGGVSGAPPGAPTTPQKYPPEMEMKFAPQDLKYPPPPPLDALKYSQEMQAAAAAAAAAGKYDMKYMMEQQGKYNVELSAAHQPPSKPGYQDSLKIPDIKPGFGHLPHNVGSPLDAAHKYGPPPTSQESQQQQPQPPAHQVPPGATPPPGIAMPKPHYQHDVQTPPLGRPFEPTGLMLKYGDPLAAKYGPPQDLKYPMPPVSQAGPADVKPYGGENLIKSSPYGPPPESPIDASARSTPGQDSQGSNSNSQPPSMPPQPQQFQSPHPSPHMPSPAGGGLPPGMHPQNLIHGPPPGAAGGSGPQPPPPPTSLHQPTPTSAGPPSLQHGLHPGHQHSQLSVASSIPPSSIGIPPTLSTMAPSHMHPHLHPHAHLQGLHRPHDLPPSMHPHAPMPLSLQGHPQHGHGLPPSHTSQQQQQQQQQQQPGGPAGTVRTPSPAQQPPRSMHDPQSSREPPTSQPSTTMAGSSGPGGPPPQQSPHAHRTSPLPGLAGSGPPPPGLIGHPMAIHPHLAHLPPGHPAHAALAHPGHHLLSHSIAGLGPGGGPIALLAGPGGLGGIPESALSRRTPPSHLPHSHASSAPLTAHSVASMTSTSMSLTTSTVPSSAFSRASPSVQISSSGGGPSGPGSVGPGGMPNSSAAAAAAAAAHRAASPASSVSSLSRQSPLHPVPQSPLSHHPSSSALSAAAAAVAERDRHALMRQQSPHMTPPPVSNASLMASPLSKMYAPQPGQRGLGTSPPPHLRPGASPPVIRHPQMPLPLPLIAPGGGIPQIGVHPGQSPYPHPLLHPSVFYSPHHHPFNSPYGYAPYGPGFPAYMKPPPQPGQLDPAAVMAAHHAGLQGPPPQQMRQDEQNAAAAAAQAAAEKQHQAAAAAAAQQHKAPQQQQPGGMPPNKPPTPKTPQGPGGGMPPGMGGPGTPTGLPPGAYPGSHMPGYPQGPPHGSPFAPQDGQPHGLKPTSHMDALRAHAHSANSAGMGGGHHPTEPLPIDIEPDPEPEIPSPTHNIPRGPSPEAKPDDTECHRSQSAIFVRHIDRGDYNSCTRTDLIFKPVADSKLARKREERDRKLAEKERERRQQQQQQQQQQQQQQAAAAQQAAQQAKMKAELKPPYADTPALRQLSEYARPHVAFSPVEQMVPYHHPMGPMYRERELEEIKNAQAAAASQSRLDPHWMEYYRRGIHPSQFPLYANPAISQMERERLGIPPPHHVGLDPGEHMIRLTREYHAHSHTHLHLPLHPQPQPPEAGFQLPPNVGQYPRPNMLIPREPHSDVLLRMSYADQLQYLQAAEFQRQSLHDQYFRNQLR", "length": 2007 }, "evidence": [ { "id": "HGNC:9965", "url": "https://alliancegenome.org/gene/HGNC:9965#orthology", "database": "AGR" }, { "id": "MGI:2683486", "url": "https://alliancegenome.org/gene/MGI:2683486#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q62901-1", "protein_name": "Arginine-glutamic acid dipeptide repeats protein", "gene_name": "Rere", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTADKDKDKDKEKDRDRDRDRERDKRDKARESENARPRRSCTLEGGAKNYAESDHSEDEDNDNGATTEESARKSRKKPPKKKSRYERTDTGEITSYITEDDVVYRPGDCVYIESRRPNTPYFICSIQDFKLVHNSQACCRSPAPALCDPPACSLPVASQPPQHLSEAGRGPVGSKRDHLLMNVKWYYRQSEVPDSVYQHLVQDRHNENDSGRELVITDPVIKNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARVDSFFYILGYNPETRRLNSTQGEIRVGPSHQAKLPDLQPFPSPDGDTVTQHEELVWMPGVSDCDLLMYLRAARSMAAFAGMCDGGSTEDGCVAASRDDTTLNALNTLHESSYDAGKALQRLVKKPVPKLIEKCWTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKKTPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSEFLDLSSASEDDFDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRASPVNEDVRSSGRNSPSAASTSSNDSKAEAVKKSAKKVKEEAASPLKNTKRQREKVASDTEDTDRATSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQTQPPALQAPSGAASAPSTAPPGTTQLPTPGPTPSATTVPPQGSPATSQPPNQTQSTVAPAAHTLIQQTPTLHPPRLPSPHPPLQPMTAPPSQNSAQPHPQPSLHGQGPPGPHSLQTGPLLQHPGPPQPFGLTPQSSQGQGPLGPSPAAAHPHSTIQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTTGGLHQVPSQSPFPQHPFVPGGPPPITPPSCPPTSTPPAGPSSSSQPPCSAAVSSGGNVPGAPSCPLPAVQIKEEALDEAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAQKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHSALTIPPAAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL", "length": 1559 }, "evidence": [ { "id": "HGNC:9965", "url": "https://alliancegenome.org/gene/HGNC:9965#orthology", "database": "AGR" }, { "id": "MGI:2683486", "url": "https://alliancegenome.org/gene/MGI:2683486#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q80TZ9-1", "protein_name": "Arginine-glutamic acid dipeptide repeats protein", "gene_name": "Rere", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTADKDKDKDKEKDRDRDRDRERDKRDKARESENARPRRSCTLEGGAKNYAESDHSEDEDNDNNSATTEESNKKSRKKPPKKKSRYERTDTGEITSYITEDDVVYRPGDCVYIESRRPNTPYFICSIQDFKLVHSSQACCRSPAPAFCDPPACSLPVAPQPPQHLSEAGRGPGGSKRDHLLMNVKWYYRQSEVPDSVYQHLVQDRHNENDSGRELVITDPVIKNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARVDSFFYILGYNPETRRLNSTQGEIRVGPSHQAKLPDLQPFPSPDGDTVTQHEELVWMPGVSDCDLLMYLRAARSMAAFAGMCDGGSTEDGCVAASRDDTTLNALNTLHESSYDAGKALQRLVKKPVPKLIEKCWTEDEVKRFVKGLRQYGKNFFRIRKELLPSKETGELITFYYYWKKTPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSEFLDLSSASEDDFDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPTSPDGRASPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEAASPLKSTKRQREKVASDTEDTDRITSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPSGAASAPSTAPPGTPQLPTQGPTPSATAVPPQGSPATSQPPNQTQSTVAPAAHTHIQQAPTLHPPRLPSPHPPLQPMTAPPSQSSAQPHPQPSLHSQGPPGPHSLQTGPLLQHPGPPQPFGLPSQPSQGQGPLGPSPAAAHPHSTIQLPASQSALQPQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSLNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQSLPPPAASHPTTGLHQVPSQSPFPQHPFVPGGPPPITPPSCPPTSTPPAGPSSSSQPPCSAAVSSGGSVPGAPSCPLPAVQIKEEALDEAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPATNPMEHFARHSALTIPPAAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL", "length": 1558 }, "evidence": [ { "id": "HGNC:9965", "url": "https://alliancegenome.org/gene/HGNC:9965#orthology", "database": "AGR" }, { "id": "MGI:2683486", "url": "https://alliancegenome.org/gene/MGI:2683486#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070212-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070212-3#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9P2R6-1", "protein_name": "Arginine-glutamic acid dipeptide repeats protein", "gene_name": "RERE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTADKDKDKDKEKDRDRDRDREREKRDKARESENSRPRRSCTLEGGAKNYAESDHSEDEDNDNNSATAEESTKKNKKKPPKKKSRYERTDTGEITSYITEDDVVYRPGDCVYIESRRPNTPYFICSIQDFKLVHNSQACCRSPTPALCDPPACSLPVASQPPQHLSEAGRGPVGSKRDHLLMNVKWYYRQSEVPDSVYQHLVQDRHNENDSGRELVITDPVIKNRELFISDYVDTYHAAALRGKCNISHFSDIFAAREFKARVDSFFYILGYNPETRRLNSTQGEIRVGPSHQAKLPDLQPFPSPDGDTVTQHEELVWMPGVNDCDLLMYLRAARSMAAFAGMCDGGSTEDGCVAASRDDTTLNALNTLHESGYDAGKALQRLVKKPVPKLIEKCWTEDEVKRFVKGLRQYGKNFFRIRKELLPNKETGELITFYYYWKKTPEAASSRAHRRHRRQAVFRRIKTRTASTPVNTPSRPPSSEFLDLSSASEDDFDSEDSEQELKGYACRHCFTTTSKDWHHGGRENILLCTDCRIHFKKYGELPPIEKPVDPPPFMFKPVKEEDDGLSGKHSMRTRRSRGSMSTLRSGRKKQPASPDGRTSPINEDIRSSGRNSPSAASTSSNDSKAETVKKSAKKVKEEASSPLKSNKRQREKVASDTEEADRTSSKKTKTQEISRPNSPSEGEGESSDSRSVNDEGSSDPKDIDQDNRSTSPSIPSPQDNESDSDSSAQQQMLQAQPPALQAPTGVTPAPSSAPPGTPQLPTPGPTPSATAVPPQGSPTASQAPNQPQAPTAPVPHTHIQQAPALHPQRPPSPHPPPHPSPHPPLQPLTGSAGQPSAPSHAQPPLHGQGPPGPHSLQAGPLLQHPGPPQPFGLPPQASQGQAPLGTSPAAAYPHTSLQLPASQSALQSQQPPREQPLPPAPLAMPHIKPPPTTPIPQLPAPQAHKHPPHLSGPSPFSMNANLPPPPALKPLSSLSTHHPPSAHPPPLQLMPQSQPLPSSPAQPPGLTQSQNLPPPPASHPPTGLHQVAPQPPFAQHPFVPGGPPPITPPTCPSTSTPPAGPGTSAQPPCSGAAASGGSIAGGSSCPLPTVQIKEEALDDAEEPESPPPPPRSPSPEPTVVDTPSHASQSARFYKHLDRGYNSCARTDLYFMPLAGSKLAKKREEAIEKAKREAEQKAREEREREKEKEKEREREREREREAERAAKASSSAHEGRLSDPQLSGPGHMRPSFEPPPTTIAAVPPYIGPDTPALRTLSEYARPHVMSPTNRNHPFYMPLNPTDPLLAYHMPGLYNVDPTIRERELREREIREREIRERELRERMKPGFEVKPPELDPLHPAANPMEHFARHSALTIPPTAGPHPFASFHPGLNPLERERLALAGPQLRPEMSYPDRLAAERIHAERMASLTSDPLARLQMFNVTPHHHQHSHIHSHLHLHQQDPLHQGSAGPVHPLVDPLTAGPHLARFPYPPGTLPNPLLGQPPHEHEMLRHPVFGTPYPRDLPGAIPPPMSAAHQLQAMHAQSAELQRLAMEQQWLHGHPHMHGGHLPSQEDYYSRLKKEGDKQL", "length": 1566 }, "evidence": [ { "id": "HGNC:9965", "url": "https://alliancegenome.org/gene/HGNC:9965#orthology", "database": "AGR" }, { "id": "MGI:2683486", "url": "https://alliancegenome.org/gene/MGI:2683486#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070212-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070212-3#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "E7FCG5", "url": "https://www.uniprot.org/uniprotkb/E7FCG5" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7FCG5", "url": "https://www.uniprot.org/uniprotkb/E7FCG5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E7FCG5", "url": "https://www.uniprot.org/uniprotkb/E7FCG5" } ], "pmid": "" }, { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "E7FCG5", "url": "https://www.uniprot.org/uniprotkb/E7FCG5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7FCG5", "url": "https://www.uniprot.org/uniprotkb/E7FCG5" } ], "pmid": "" }, { "name": "sequence-specific DNA binding", "id": "GO:0043565", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043565", "evidence": [ { "database": "UniProtKB", "id": "E7FCG5", "url": "https://www.uniprot.org/uniprotkb/E7FCG5" } ], "pmid": "" }, { "name": "transcription corepressor activity", "id": "GO:0003714", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003714", "evidence": [ { "database": "UniProtKB", "id": "E7FCG5", "url": "https://www.uniprot.org/uniprotkb/E7FCG5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1074, "end_pos": 1076, "annotation": "n_glycosylation_sequon" }, { "start_pos": 12, "end_pos": 14, "annotation": "n_glycosylation_sequon" }, { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 204, "end_pos": 206, "annotation": "n_glycosylation_sequon" }, { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" }, { "start_pos": 454, "end_pos": 456, "annotation": "n_glycosylation_sequon" }, { "start_pos": 548, "end_pos": 550, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FCG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCG5" }, { "id": "PS51156", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51156" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELM2", "eco_id": "ECO_0000259", "start_pos": 16, "end_pos": 119, "start_aa": "Gly", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7FCG5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCG5" }, { "id": "PS51293", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51293" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SANT", "eco_id": "ECO_0000259", "start_pos": 123, "end_pos": 175, "start_aa": "Leu", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1074, "end_pos": 1076 }, { "start_pos": 12, "end_pos": 14 }, { "start_pos": 198, "end_pos": 200 }, { "start_pos": 204, "end_pos": 206 }, { "start_pos": 440, "end_pos": 442 }, { "start_pos": 454, "end_pos": 456 }, { "start_pos": 548, "end_pos": 550 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F3T1-1", "uniprot_ac": "E7F3T1", "uniprot_id": "E7F3T1_DANRE", "mass": { "chemical_mass": 85469.0, "monoisotopic_mass": 85469.0 }, "refseq": { "ac": "XP_690835", "name": "kanadaptin isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690835" }, "gene_names": [ { "name": "slc4a1ap", "type": "recommended", "evidence": [ { "id": "E7F3T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F3T1" } ] }, { "name": "slc4a1ap", "type": "synonym", "evidence": [ { "id": "XP_690835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690835" } ] } ], "protein_names": [ { "name": "Kanadaptin isoform X1", "type": "synonym", "evidence": [ { "id": "E7F3T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F3T1/entry#names_and_taxonomy" } ] }, { "name": "kanadaptin isoform X1", "type": "synonym", "evidence": [ { "id": "XP_690835", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690835" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_690835.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_690835", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690835" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F3T1", "url": "https://www.uniprot.org/uniprotkb/E7F3T1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "slc4a1ap", "url": "https://www.uniprot.org/uniprotkb/E7F3T1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080521-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080521-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000034160", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000034160", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd19856", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19856", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd22677", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22677", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "562351", "url": "https://www.ncbi.nlm.nih.gov/gene/562351", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000253", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000253", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008984", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008984", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050923", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050923", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562351", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562351", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QQAIWTF", "url": "https://omabrowser.org/oma/group/QQAIWTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AUI2", "url": "https://www.orthodb.org/?gene=A0A8M3AUI2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F3T1", "url": "https://www.orthodb.org/?gene=E7F3T1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23308", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23308", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00498", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00498", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_690835", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690835", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3AUI2", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AUI2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AUI2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AUI2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F3T1", "url": "https://www.uniprot.org/uniprotkb/E7F3T1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F3T1-1", "url": "https://www.uniprot.org/uniprotkb/E7F3T1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080521-2", "url": "https://zfin.org/ZDB-GENE-080521-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEFDGSELTENIPTETMKTEKSQDPENGKICDSKQDITSTNETADDPFKKPVLTPSLAVKKSLGPSKKPTEEVSSSVSENTDADHDTKHLLSTAKAKDTKIDPSDHPPSERLKEPRVQPKSKDIRPKIPPAGKFPPLPYTEPPWGAVPDINYSFELLKNGAILDTVPLTHRSYFVVGRLPVCDVSLEHPSISRYHAVVQYRGRAGQEGVVGEERGFYAYDLGSTHGTFINKNKIPPKTYIRLRVGHVLKFGGSTRLFILQGPEFDEEAESEMTVTELRERARKQREELERRMMGDGSDEEEEKEESETSASKNTSEDAGCSWGMAEEAAPEEDDNEENPFATEFQEDQEAAYLKDPKKALQGFYDREGEELEFEYEDKAHGTWLCRIKLPVDDAVGRQLVAEVTHTGKKKEAAVQCCLEACRILEARGLLRQEAVSRKRKKKNWEDDDFYDSDDDTFLDRTGVVEKKRTERMKKAGKIQERPDTYESLLAKLADVEKELADTEKKLNLSGKGGSGSSTEDPLDAFMTAVRSEVALDGVERKKLHLHIADLKKEGQRLSRLVELAKPTQLPSLLSSGSHTQSSDSDKPKKLSLPMFGAMKGGSKFKLKTGTIGNLPPKRTSLPPELFTMKEMPPGGEEEVEEEENSEAEDVVTDGDMEVIQSVETAISEHSADSAESQTQQPKEEHEDQPAKTVISPKKDDPSPKGVNNKASNVQNPKTCAKKKVIGPSKPPVTMSKQYPEDDPDYCVWVPPSGQTGDGRTHLNDKYGY", "length": 768, "header": "tr|E7F3T1-1|E7F3T1_DANRE Isoform 1 of Kanadaptin isoform X1 OS=Danio rerio OX=7955 GN=slc4a1ap PE=1 SV=1 CANONICAL=E7F3T1-1" }, "isoforms": [ { "isoform_ac": "A0A8M3AUI2-1", "url": "https://www.uniprot.org/uniprotkb/E7F3T1/entry#A0A8M3AUI2-1", "sequence": { "sequence": "MEFDGSELTENIPTETMKTEKSQDPENGKICDSKQDITSTNETADDPFKKPVLTPSLAVKKSLGPSKKPTEEVSSSVSENTDADHDTKHLLSTAKAKDTKIDPSDHPPSERLKEPRVQPKSKDIRPKIPPAGKFPPLPYTEPPWGAVPDINYSFELLKNGAILDTVPLTHRSYFVVGRLPVCDVSLEHPSISRYHAVVQYRGRAGQEGVVGEERGFYAYDLGSTHGTFINKNKIPPKTYIRLRVGHVLKFGGSTRLFILQGPEFDEEAESEMTVTELRERARKQREELERRMMGDGSDEEEEKEESETSASKNTSEDAGCSWGMAEEAAPEEDDNEENPFATEFQEDQEAAYLKDPKKALQGFYDREGEELEFEYEDKAHGTWLCRIKLPVDDAVGRQLVAEVTHTGKKKEAAVQCCLEACRILEARGLLRQEAVSRKRKKKNWEDDDFYDSDDDTFLDRTGVVEKKRTERMKKAGKIQERPDTYESLLAKLADVEKELADTEKKLNLSGKGGSGSSTEDPLDAFMTAVRSEVALDGVERKKLHLHIADLKKEGQRLSRLVELAKPTQLPSLLSSGSHTQSSDSDKPKKLSLPMFGAMKGGSKFKLKTGTIGNLPPKRTSLPPELFTMKEMPPGGEEEVEEEENSEAEDVVTDGDMEVIQSVETAISEHSADSAESQTQQPKEHEDQPAKTVISPKKDDPSPKGVNNKASNVQNPKTCAKKKVIGPSKPPVTMSKQYPEDDPDYCVWVPPSGQTGDGRTHLNDKYGY", "length": 767, "header": "tr|A0A8M3AUI2-1|E7F3T1_DANRE Computationally mapped isoform of Kanadaptin isoform X1 OS=Danio rerio OX=7955 GN=slc4a1ap PE=1 SV=1 CANONICAL=E7F3T1-1" }, "locus": {} }, { "isoform_ac": "E7F3T1-1", "url": "https://www.uniprot.org/uniprotkb/E7F3T1/entry#E7F3T1-1", "sequence": { "sequence": "MEFDGSELTENIPTETMKTEKSQDPENGKICDSKQDITSTNETADDPFKKPVLTPSLAVKKSLGPSKKPTEEVSSSVSENTDADHDTKHLLSTAKAKDTKIDPSDHPPSERLKEPRVQPKSKDIRPKIPPAGKFPPLPYTEPPWGAVPDINYSFELLKNGAILDTVPLTHRSYFVVGRLPVCDVSLEHPSISRYHAVVQYRGRAGQEGVVGEERGFYAYDLGSTHGTFINKNKIPPKTYIRLRVGHVLKFGGSTRLFILQGPEFDEEAESEMTVTELRERARKQREELERRMMGDGSDEEEEKEESETSASKNTSEDAGCSWGMAEEAAPEEDDNEENPFATEFQEDQEAAYLKDPKKALQGFYDREGEELEFEYEDKAHGTWLCRIKLPVDDAVGRQLVAEVTHTGKKKEAAVQCCLEACRILEARGLLRQEAVSRKRKKKNWEDDDFYDSDDDTFLDRTGVVEKKRTERMKKAGKIQERPDTYESLLAKLADVEKELADTEKKLNLSGKGGSGSSTEDPLDAFMTAVRSEVALDGVERKKLHLHIADLKKEGQRLSRLVELAKPTQLPSLLSSGSHTQSSDSDKPKKLSLPMFGAMKGGSKFKLKTGTIGNLPPKRTSLPPELFTMKEMPPGGEEEVEEEENSEAEDVVTDGDMEVIQSVETAISEHSADSAESQTQQPKEEHEDQPAKTVISPKKDDPSPKGVNNKASNVQNPKTCAKKKVIGPSKPPVTMSKQYPEDDPDYCVWVPPSGQTGDGRTHLNDKYGY", "length": 768, "header": "tr|E7F3T1-1|E7F3T1_DANRE Isoform 1 of Kanadaptin isoform X1 OS=Danio rerio OX=7955 GN=slc4a1ap PE=1 SV=1 CANONICAL=E7F3T1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:562351", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562351", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A1K0-1", "protein_name": "Solute carrier family 4 member 1 adaptor protein", "gene_name": "Slc4a1ap", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MADATSQLEAPAPQDVSSEFKKPVLPVPPAVRSKAPASSPSVPEDVKKECSTAQLDSGCGEPEVSPPQPDSEETGGPPVEQLRSPRVAPASGGPTRAPPYQEPSWGSPATAPYSLETLKGGTILGTRTLKDTSYCLFGRLASCDICLEHPSVSRYHAVLQHRGSDPSGDSEDQGQGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVIRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQALLEKKMLGEDSDEEDEADTTAGKRNTSGQDEEMGCTWGMGEDAVEDEAEENPIALEFQQDREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLVEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSKVQSESSSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKLVKPAEIPELKKTELQTTNAENKTKKLALPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPALMQMKDEPEVEEEEEEEEEEKAKEEHEEGVEDGGVRLSQGPEPEPEAAGEHPGAPPEPSCSKETKSHEKHSHMEQSKGYQEMGKIMPSREDPSAAPENECKKDRDELKKKKSGPGKFPPILSSKYPEDDPDYCVWVPPEGQSGDGRTHLNDKYGY", "length": 738 }, "evidence": [ { "id": "HGNC:13813", "url": "https://alliancegenome.org/gene/HGNC:13813#orthology", "database": "AGR" }, { "id": "MGI:1196608", "url": "https://alliancegenome.org/gene/MGI:1196608#orthology", "database": "AGR" }, { "id": "E7F3T1", "url": "https://omabrowser.org/oma/group/E7F3T1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZCH4-1", "protein_name": "Solute carrier family 4 member 1 adaptor protein", "gene_name": "SLC4A1AP", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAEAMETEAEPGEFKRPSRPLPAPQSAEPGPAPSPGPAPPRPAASAPAPRYEEPPWGSRPPADAGYGLEVLKGGVLLGSVRLEGGSWFLVGRLPGCALALEHPSVSRHHAVLQYRGRSADGPDADAGFYVYDLGSTHGTFLNKARVPPRTYCRVRVGHGLRFGGSSRLFLLQGPEEDQESESELTMTQLKALRKQQQAKLEKTMLGEDSDEEDEKEERGSESSQNVDMSCSWGMGEDAEEDEAEENPIAIEFQDVQDAFYMKDPRKALQGFFDREGEELEYEYDDRGHNSWLCRVKLPVDDALGKQLVAEVLHSGKKKEAMIQCALEACRLLDARGVLRQEAVSRKRKSKNWEDEDFYDSDDDTFLDRTGAVEKKRLNRMKKAGKIEEKPETYDSLVAKLKEAENELSEITEKLKASGRGQSQPAAQDSLDEFMTEIKSGSTLDSVTRKKLHLRSFELKKEQQRLKGLIKLVKPTELPELKPPTGSYSLEANSKSKKITLPLFGAMKGGSKFKLKTGSLGKLPDKRPHIPESLLKMKDDGPEEEEEEEEEEIEEEQKVDAVSSRTSDVEMKATVEEETGKETNGPNGSTCNNEDLESLQDGVSFQPEPKILRNKSQMGPSQEKSQASEAVCKESRETSEEVKKSNTSSKLQQPFFSSQYPDDDPDYCIWIPPADQSGDGKTHLNDKYGY", "length": 689 }, "evidence": [ { "id": "E7F3T1", "url": "https://omabrowser.org/oma/group/E7F3T1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E2QCZ5-1", "protein_name": "FHA domain-containing protein", "gene_name": "Dmel\\CG7706", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNEFKVPAPLPKPKVIITEKPRSEVPAEPPPPPLKIPKTPKSSPAAVCPYKVPKWSAPPAENQIYSFEVLKSGQIIDTVHQLQQQAVWTFGRLPENDVPAAHPTISRFHVVLQYKPKAPPKPETAKEDDEMEEEDEEPKNDQPEGWYIYDMGSTHGTFLNKQRVPPKVYIRMRVGHMLKLGGSTRVYILQGPGEDEEPESELSVTELRQKREKELADAAVERELRLLEAEERERNEGVSWGMGDDADEETDLSHNPYASTNNEELFFDDPKKTLRGFFEREGLNLEYKCDELSTGSFVCRVELPLDDSNGRPIIVEVNHKGRKKDCVVQCALEACRTLDRHGVLRQANQEAQKRKQLKNRDSDDEDEFWDRTGDVARKKQRKDNAGVSVTLTYEDLLKQEIDLNMEMEKVEQEISTYQQNEKKLKELAAKQQAEGDDLDNFMDMLTKDVEQLDKTEIKKLRLEQQRIKGEQQKVERLLKIAKPTALPFTTSLAAGSKESAAQEGGAAKKKQLPMIGKRNQFSKFKVVKASPSTQTMTQSNAFASDEEEVEEEEVKEKVKEKEAEVDNLEKEETEPESTTKPSTPENDSLKETKLPAQPEESKPTVAKTEVLKPENVRSTKVSTEAPPAPSHTVASTNPDEDMSTPVEDSSAPAEDITARANDTSEPEEAQKKRRQRQRQRNKQRQDVDMDLDELAEHEDTEKYAKWVPPTNQSGDGITHLNEKFGY", "length": 726 }, "evidence": [ { "id": "HGNC:13813", "url": "https://alliancegenome.org/gene/HGNC:13813#orthology", "database": "AGR" }, { "id": "MGI:1196608", "url": "https://alliancegenome.org/gene/MGI:1196608#orthology", "database": "AGR" }, { "id": "E7F3T1", "url": "https://omabrowser.org/oma/group/E7F3T1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "E9PX68-1", "protein_name": "Solute carrier family 4 (anion exchanger), member 1, adaptor protein", "gene_name": "Slc4a1ap", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MADPTPQLDAPAPQEVSSEFKKPVLPVPSAVRGKAPASSPSVSEDVKKECLAAQLDSGCEEPEVPPPQPDSQETGGPPVEQLRSPRVAPASGGPTRAPPYREPSWGSPATAPYSLETLKGGTILGTRTLKDTSCCFFGRLASCDICLEHPSVSRYHAVLQHRGADPSGDSEGHEQGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVMRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEANTTEGKSSRSGQDDELGCTWGMGEDAVEDEAEENPIALDFQQDREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMVQCSLEACRVLDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLVEKKRLNRMKKAGKLDEKPETFESLVAKLNDAERELAEISERLKASSKVLSEPSSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKLVKPAEIPELKKTELQTTNAENKTKKLALPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPALMQMKDEPEVEEEEEEEEEEEEKVKEEHEERVEDGGVRLLQEPELELEAAVEHPSAPSEPSCSKETKSHESISQLSQVEQSKDYQEMGKIVSSCEDPSAAPANEYKQDRDEPKKKKSPGPGKFPPILSSKYPEDDPDYCIWVPPEGQSGDGRTHLNDKYGY", "length": 744 }, "evidence": [ { "id": "HGNC:13813", "url": "https://alliancegenome.org/gene/HGNC:13813#orthology", "database": "AGR" }, { "id": "MGI:1196608", "url": "https://alliancegenome.org/gene/MGI:1196608#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080521-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080521-2#orthology", "database": "AGR" }, { "id": "E7F3T1", "url": "https://omabrowser.org/oma/group/E7F3T1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BWU0-2", "protein_name": "Kanadaptin", "gene_name": "SLC4A1AP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MADILSQSETLASQDLSGDFKKPALPVSPAARSKAPASSSSNPEEVQKEGPTALQDSNSGEPDIPPPQPDCGDFRSLQEEQSRPPTAVSSPGGPARAPPYQEPPWGGPATAPYSLETLKGGTILGTRSLKGTSYCLFGRLSGCDVCLEHPSVSRYHAVLQHRASGPDGECDSNGPGFYLYDLGSTHGTFLNKTRIPPRTYCRVHVGHVVRFGGSTRLFILQGPEEDREAESELTVTQLKELRKQQQILLEKKMLGEDSDEEEEMDTSERKINAGSQDDEMGCTWGMGEDAVEDDAEENPIVLEFQQEREAFYIKDPKKALQGFFDREGEELEYEFDEQGHSTWLCRVRLPVDDSTGKQLVAEAIHSGKKKEAMIQCSLEACRILDTLGLLRQEAVSRKRKAKNWEDEDFYDSDDDTFLDRTGLIEKKRLNRMKKAGKIDEKPETFESLVAKLNDAERELSEISERLKASSQVLSESPSQDSLDAFMSEMKSGSTLDGVSRKKLHLRTFELRKEQQRLKGLIKIVKPAEIPELKKTETQTTGAENKAKKLTLPLFGAMKGGSKFKLKTGTVGKLPPKRPELPPTLMRMKDEPEVEEEEEEEEEEEKEKEEHEKKKLEDGSLSRPQPEIEPEAAVQEMRPPTDLTHFKETQTHENMSQLSEEEQNKDYQDCSKTTSLCAGPSASKNEYEKSRGELKKKKTPGPGKLPPTLSSKYPEDDPDYCVWVPPEGQSGDGRTHLNDKYGY", "length": 742 }, "evidence": [ { "id": "HGNC:13813", "url": "https://alliancegenome.org/gene/HGNC:13813#orthology", "database": "AGR" }, { "id": "MGI:1196608", "url": "https://alliancegenome.org/gene/MGI:1196608#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080521-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080521-2#orthology", "database": "AGR" }, { "id": "E7F3T1", "url": "https://omabrowser.org/oma/group/E7F3T1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "mRNA binding", "id": "GO:0003729", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003729", "evidence": [ { "database": "UniProtKB", "id": "E7F3T1", "url": "https://www.uniprot.org/uniprotkb/E7F3T1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" }, { "start_pos": 507, "end_pos": 509, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F3T1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F3T1" }, { "id": "PS50006", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50006" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FHA", "eco_id": "ECO_0000259", "start_pos": 174, "end_pos": 234, "start_aa": "Phe", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 151, "end_pos": 153 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 41, "end_pos": 43 }, { "start_pos": 507, "end_pos": 509 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F2M2-1", "uniprot_ac": "E7F2M2", "uniprot_id": "E7F2M2_DANRE", "mass": { "chemical_mass": 25199.0, "monoisotopic_mass": 25199.0 }, "refseq": { "ac": "NP_001373275", "name": "cilia- and flagella-associated protein 107", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373275" }, "gene_names": [ { "name": "cfap107", "type": "recommended", "evidence": [ { "id": "E7F2M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2M2" } ] }, { "name": "si:ch211-226m7.4", "type": "recommended", "evidence": [ { "id": "E7F2M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2M2" } ] }, { "name": "c11h1orf158", "type": "synonym", "evidence": [ { "id": "NP_001373275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373275" }, { "id": "E7F2M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2M2" } ] }, { "name": "cfap107", "type": "synonym", "evidence": [ { "id": "NP_001373275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373275" } ] }, { "name": "gb:dv597150", "type": "synonym", "evidence": [ { "id": "NP_001373275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373275" }, { "id": "E7F2M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2M2" } ] }, { "name": "si:ch211-226m7.4", "type": "synonym", "evidence": [ { "id": "NP_001373275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373275" }, { "id": "E7F2M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2M2" } ] } ], "protein_names": [ { "name": "Cilia- and flagella-associated protein 107", "type": "synonym", "evidence": [ { "id": "E7F2M2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2M2/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella-associated protein 107", "type": "synonym", "evidence": [ { "id": "NP_001373275", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373275" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01012657.1, GDQQ01058180.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505381, SAMEA3505385 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 25, 2025 this sequence version replaced NP_001373275.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001373275", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373275" } ] }, { "annotation": "Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M3AXR8", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AXR8#function" }, { "database": "UniProtKB", "id": "ARBA00035003", "url": "https://www.uniprot.org/uniprotkb/ARBA00035003#function" }, { "database": "UniProtKB", "id": "E7F2M2", "url": "https://www.uniprot.org/uniprotkb/E7F2M2#function" }, { "database": "UniProtKB", "id": "A0AC58GNV9", "url": "https://www.uniprot.org/uniprotkb/A0AC58GNV9#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F2M2", "url": "https://www.uniprot.org/uniprotkb/E7F2M2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cfap107", "url": "https://www.uniprot.org/uniprotkb/E7F2M2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080919-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080919-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100003307", "url": "https://www.ncbi.nlm.nih.gov/gene/100003307", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037662", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037662", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR054709", "url": "https://www.ebi.ac.uk/interpro/entry/IPR054709", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100003307", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003307", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M3AXR8", "url": "https://www.orthodb.org/?gene=A0A8M3AXR8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F2M2", "url": "https://www.orthodb.org/?gene=E7F2M2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31180", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31180", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31180:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31180:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22595", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22595", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001373275", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373275", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3AXR8", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AXR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AXR8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AXR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GNV9", "url": "https://www.uniprot.org/uniprotkb/A0AC58GNV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GNV9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GNV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GNW0", "url": "https://www.uniprot.org/uniprotkb/A0AC58GNW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GNW0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GNW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F2M2", "url": "https://www.uniprot.org/uniprotkb/E7F2M2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F2M2-1", "url": "https://www.uniprot.org/uniprotkb/E7F2M2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080919-1", "url": "https://zfin.org/ZDB-GENE-080919-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MYKMQNPYDKWSQPGWKIEQKYGNKVLIGNWVEEKLQFARECKTANSSNRLDYIPHMLHRPDVVMRRKALRRSEGVPSRQLLSHHDVPSSHYLVSLYDESYGRQTSSSLPTLRSWHHDKLAWVPERSDHPVQGPPTKFGLAECWRTRVEQQRAVVPTLSLYKASYPLHPISSFCHSRHVSMPKRFSSSQHPANHSRQELALKPRPCRQVSSNPASPL", "length": 217, "header": "tr|E7F2M2-1|E7F2M2_DANRE Isoform 1 of Cilia- and flagella-associated protein 107 OS=Danio rerio OX=7955 GN=cfap107 PE=4 SV=1 CANONICAL=E7F2M2-1" }, "isoforms": [ { "isoform_ac": "A0A8M3AXR8-1", "url": "https://www.uniprot.org/uniprotkb/E7F2M2/entry#A0A8M3AXR8-1", "sequence": { "sequence": "MYKMQNPYDKWSQPGWKIEQKYGNKVLIGNWVEEKLQFARECKTANSSNRLDYIPHMLHRPDVVMRRKALRRSETLNRFQKSWHRSSLGLSIRAFPQGSYFLIMMSRPPTTWCPCMMSLTGVRPPPLCPHCAPGTLTNWPGSQRGQTTQSKAPLLSLAWLSVGALMWNNSGQLCLH", "length": 176, "header": "tr|A0A8M3AXR8-1|E7F2M2_DANRE Computationally mapped isoform of Cilia- and flagella-associated protein 107 OS=Danio rerio OX=7955 GN=cfap107 PE=4 SV=2 CANONICAL=E7F2M2-1" }, "locus": {} }, { "isoform_ac": "A0AC58GNV9-1", "url": "https://www.uniprot.org/uniprotkb/E7F2M2/entry#A0AC58GNV9-1", "sequence": { "sequence": "MLHRPDVVMRRKALRRSEGVPSRQLLSHHDVPSSHYLVSLYDESYGRQTSSSLPTLRSWHPDKLAWVPERSDHPVQGPPTKFGLAECWRTHVEQQRAVVPTLSLYKASYPLHPISSFCHSRHVSMPKRFSSSQHPANHSRQELALKPRPCRQVSSNPASPL", "length": 161, "header": "tr|A0AC58GNV9-1|A0AC58GNV9_DANRE Computationally mapped isoform of Cilia- and flagella-associated protein 107 isoform X2 OS=Danio rerio OX=7955 GN=si:ch211-226m7.4 PE=4 SV=1 CANONICAL=E7F2M2-1" }, "locus": {} }, { "isoform_ac": "A0AC58GNW0-1", "url": "https://www.uniprot.org/uniprotkb/E7F2M2/entry#A0AC58GNW0-1", "sequence": { "sequence": "MLHRPDVVMRRKALRRSETLNRFQKSWHRSSLGLSIRAFPQGSYFLIMMSRPPTTWCPCMMSLTGVRPPPLCPHCAPGTLTNWPGSQRGQTTQSKAPLLSLAWLSVGALMWNNSGQLCLH", "length": 120, "header": "tr|A0AC58GNW0-1|A0AC58GNW0_DANRE Computationally mapped isoform of Cilia- and flagella-associated protein 107 isoform X3 OS=Danio rerio OX=7955 GN=si:ch211-226m7.4 PE=4 SV=1 CANONICAL=E7F2M2-1" }, "locus": {} }, { "isoform_ac": "E7F2M2-1", "url": "https://www.uniprot.org/uniprotkb/E7F2M2/entry#E7F2M2-1", "sequence": { "sequence": "MYKMQNPYDKWSQPGWKIEQKYGNKVLIGNWVEEKLQFARECKTANSSNRLDYIPHMLHRPDVVMRRKALRRSEGVPSRQLLSHHDVPSSHYLVSLYDESYGRQTSSSLPTLRSWHHDKLAWVPERSDHPVQGPPTKFGLAECWRTRVEQQRAVVPTLSLYKASYPLHPISSFCHSRHVSMPKRFSSSQHPANHSRQELALKPRPCRQVSSNPASPL", "length": 217, "header": "tr|E7F2M2-1|E7F2M2_DANRE Isoform 1 of Cilia- and flagella-associated protein 107 OS=Danio rerio OX=7955 GN=cfap107 PE=4 SV=1 CANONICAL=E7F2M2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7F2M2", "url": "https://www.uniprot.org/uniprotkb/E7F2M2" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "E7F2M2", "url": "https://www.uniprot.org/uniprotkb/E7F2M2" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100003307", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003307", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LV28-1", "protein_name": "Cilia and flagella associated protein 107", "gene_name": "Cfap107", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVMFSTSVVPEAFSTPGWQIEKKYSTKVLVGNWVEERGKFTKATEHTPQCNYRMEYIPLPDHRPDYISRWYTKRKMEGLPHNYLMTHHQEPWHRYLISTYDDHYNRHNYNPSLPALRTWNGQKLLWLPEKSDFPLLGPPTNYGLLEQLQQKWLAPKTGLKESIYTTSYPRLPVCAMSRREHAIPVPPTRLQPMPRS", "length": 196 }, "evidence": [ { "id": "MGI:1916614", "url": "https://alliancegenome.org/gene/MGI:1916614#orthology", "database": "AGR" }, { "id": "HGNC:28567", "url": "https://alliancegenome.org/gene/HGNC:28567#orthology", "database": "AGR" }, { "id": "E7F2M2", "url": "https://omabrowser.org/oma/group/E7F2M2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2TA11-1", "protein_name": "Cilia- and flagella-associated protein 107", "gene_name": "CFAP107", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQFLTAVSPQSSSTPSWKIETKYSTRVLTGNWTEERRKFIKATEKTPQTIYRKEYVPFPGHRPDQISRWYSKRTVEGLPYKYLITHHQEPSQRYLISTYDDHYNRHNYHPGLPELRTWNRHKLLWLPEKADFPLLGPPTNYGLYEQLKQKWLPPPEATLRESIYTSSYPRPPAGAMSRREHAIPVPPPRLQPVPHF", "length": 196 }, "evidence": [ { "id": "E7F2M2", "url": "https://omabrowser.org/oma/group/E7F2M2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4KKZ1-1", "protein_name": "Cilia- and flagella-associated protein 107", "gene_name": "Cfap107", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAMLSTSVVPEAFSTPGWQIEKKYSTKVLLGNWVEERGKFTKAIDHTPQCIYRKEYVPMPDHRPDFVSRWYSKSKMEGLPYKHLITHHQEPSHRYLISTYDDHYNRHNYNPGLPALRTWNGQKLLWLPEKSDFPLVAPPTNYGLLEQLQQKWLASKTSLKESIYTTSYPRLPVCAMSRREHAIPVPHPRLQPIPRF", "length": 196 }, "evidence": [ { "id": "MGI:1916614", "url": "https://alliancegenome.org/gene/MGI:1916614#orthology", "database": "AGR" }, { "id": "HGNC:28567", "url": "https://alliancegenome.org/gene/HGNC:28567#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080919-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080919-1#orthology", "database": "AGR" }, { "id": "E7F2M2", "url": "https://omabrowser.org/oma/group/E7F2M2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N1D5-1", "protein_name": "Cilia- and flagella-associated protein 107", "gene_name": "CFAP107", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLTAVNPQPLSTPSWQIETKYSTKVLTGNWMEERRKFTRDTDKTPQSIYRKEYIPFPDHRPDQISRWYGKRKVEGLPYKHLITHHQEPPHRYLISTYDDHYNRHGYNPGLPPLRTWNGQKLLWLPEKSDFPLLAPPTNYGLYEQLKQRQLTPKAGLKQSTYTSSYPRPPLCAMSWREHAVPVPPHRLHPLPHF", "length": 194 }, "evidence": [ { "id": "MGI:1916614", "url": "https://alliancegenome.org/gene/MGI:1916614#orthology", "database": "AGR" }, { "id": "HGNC:28567", "url": "https://alliancegenome.org/gene/HGNC:28567#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080919-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080919-1#orthology", "database": "AGR" }, { "id": "E7F2M2", "url": "https://omabrowser.org/oma/group/E7F2M2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "flagellated sperm motility", "id": "GO:0030317", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030317", "evidence": [ { "database": "UniProtKB", "id": "E7F2M2", "url": "https://www.uniprot.org/uniprotkb/E7F2M2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "axoneme", "id": "GO:0005930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005930", "evidence": [ { "database": "UniProtKB", "id": "E7F2M2", "url": "https://www.uniprot.org/uniprotkb/E7F2M2" } ], "pmid": "" }, { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "E7F2M2", "url": "https://www.uniprot.org/uniprotkb/E7F2M2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1Q4L6-1", "uniprot_ac": "F1Q4L6", "uniprot_id": "F1Q4L6_DANRE", "mass": { "chemical_mass": 64731.0, "monoisotopic_mass": 64731.0 }, "refseq": { "ac": "NP_001093452", "name": "transcription factor Sp2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093452" }, "gene_names": [ { "name": "sp2", "type": "recommended", "evidence": [ { "id": "F1Q4L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6" } ] }, { "name": "sp2", "type": "synonym", "evidence": [ { "id": "NP_001093452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093452" } ] } ], "protein_names": [ { "name": "Transcription factor Sp2", "type": "recommended", "evidence": [ { "id": "F1Q4L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6/entry#names_and_taxonomy" } ] }, { "name": "transcription factor Sp2", "type": "synonym", "evidence": [ { "id": "NP_001093452", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093452" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01039343.1, EF613286.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Jun 16, 2025 this sequence version replaced NP_001093452.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001093452", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093452" } ] }, { "annotation": "Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.", "evidence": [ { "database": "UniProtKB", "id": "A0A8M3B3X7", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B3X7#function" }, { "database": "UniProtKB", "id": "ARBA00056082", "url": "https://www.uniprot.org/uniprotkb/ARBA00056082#function" }, { "database": "UniProtKB", "id": "F1Q4L6", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6#function" } ] }, { "annotation": "Data show that the intron/exon organization and amino acid sequence of zebrafish Sp2 is closely conserved with its mammalian orthologues.", "evidence": [ { "database": "RefSeq", "id": "NP_001093452", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093452" }, { "database": "PubMed", "id": "19959469", "url": "https://glygen.org/publication/PubMed/19959469" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q4L6", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sp2", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080410-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080410-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000076763", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000076763", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22540", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22540", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "556835", "url": "https://www.ncbi.nlm.nih.gov/gene/556835", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556835", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556835", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RRANVVM", "url": "https://omabrowser.org/oma/group/RRANVVM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3B3X7", "url": "https://www.orthodb.org/?gene=A0A8M3B3X7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1Q4L6", "url": "https://www.orthodb.org/?gene=F1Q4L6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001093452", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093452", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3B3X7", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B3X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B3X7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B3X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q4L6", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q4L6-1", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080410-1", "url": "https://zfin.org/ZDB-GENE-080410-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSDQKDSMATTVAVSPSEYLQPSTTTSQDSQPSPLALLAATCSKIGPPAAQAPVSTPPSQPTTRRLHPIKPAPIAPAPPKNLGFLSAKGNIIQLPAGLGSSGASPIVFTFQSPSRPAGTSTANFQYQVIPQFQGSQTIQMMPQGGQIQIIPGTNQAIITSPVTVQAATPTAPPLAPAPVPQHKTVAIKPSTQKRRQNNASVNANIVRLPSGLTLPLNVTTGDVGGAQVLTETAAAPVKPKRGRKRQVAIAAPAPAPQPASPPPVAEQVEALLIETTADNIIQAGNNLLIVQNPGGSQPAVVQQVQLLQQKSDQQVVQIPPQALKVVQAASATLPPVPQRQTVTPSVQVSPPEPTQVLIKTASGEWQAVQIQETTVTTPTTPTSTPTPAVVTKKVQTGTRKERTLPKIAPAGGGLITLNAAQLASAAQAVQTININGVQVQGVPVTITNAGGQQHLTVQTVPSAGLQLGSVQTQTQTMQIEQTQTLALELQTQPGEKKRRMACTCPNCKDAEKKPGEVGKRKHICHIAGCEKTFRKTSLLRAHVRLHTGERPFVCNWVFCGKRFTRSDELQRHARTHTGDKRFECNKCQKRFMRSDHLTKHYKTHINTKSL", "length": 610, "header": "tr|F1Q4L6-1|F1Q4L6_DANRE Isoform 1 of Transcription factor Sp2 OS=Danio rerio OX=7955 GN=sp2 PE=1 SV=1 CANONICAL=F1Q4L6-1" }, "isoforms": [ { "isoform_ac": "A0A8M3B3X7-1", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6/entry#A0A8M3B3X7-1", "sequence": { "sequence": "MATTVAVSPSEYLQPSTTTSQDSQPSPLALLAATCSKIGPPAAQAPVSTPPSQPTTRRLHPIKPAPIAPAPPKNLGFLSAKGNIIQLPAGLGSSGASPIVFTFQSPSRPAGTSTANFQYQVIPQFQGSQTIQMMPQGGQIQIIPGTNQAIITSPVTVQAATPTAPPLAPAPQHKTVAIKPSTQKRRQNNASVNANIVRLPSGLTLPLNVTTGDVGGAQVLTETAAAPVKPKRGRKRQVAMAAPAPAPQPASPPPVAEQVEALLIETTADNIIQAGNNLLIVQNPGGSQPAVVQQVQLLQQKSDQQVVQIPPQALKVVQAASATLPPVPQRQTVTPSVQVSPPEPTQVLIKTASGEWQAVQIQETTVTTPTTPTSTPTPAVVTKKVQTGTRKERTLPKIAPAGGGLITLNAAQLASAAQAVQTININGVQVQGVPVTITNAGGQQHLTVQTVPSAGLQLGSVQTQTQTMQIEQTQTLALELQTQPGEKKRRMACTCPNCKDAEKKPGEVGKRKHICHIAGCEKTFRKTSLLRAHVRLHTGERPFVCNWVFCGKRFTRSDELQRHARTHTGDKRFECNKCQKRFMRSDHLTKHYKTHINTKSL", "length": 601, "header": "tr|A0A8M3B3X7-1|F1Q4L6_DANRE Computationally mapped isoform of Transcription factor Sp2 OS=Danio rerio OX=7955 GN=sp2 PE=1 SV=2 CANONICAL=F1Q4L6-1" }, "locus": {} }, { "isoform_ac": "F1Q4L6-1", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6/entry#F1Q4L6-1", "sequence": { "sequence": "MSDQKDSMATTVAVSPSEYLQPSTTTSQDSQPSPLALLAATCSKIGPPAAQAPVSTPPSQPTTRRLHPIKPAPIAPAPPKNLGFLSAKGNIIQLPAGLGSSGASPIVFTFQSPSRPAGTSTANFQYQVIPQFQGSQTIQMMPQGGQIQIIPGTNQAIITSPVTVQAATPTAPPLAPAPVPQHKTVAIKPSTQKRRQNNASVNANIVRLPSGLTLPLNVTTGDVGGAQVLTETAAAPVKPKRGRKRQVAIAAPAPAPQPASPPPVAEQVEALLIETTADNIIQAGNNLLIVQNPGGSQPAVVQQVQLLQQKSDQQVVQIPPQALKVVQAASATLPPVPQRQTVTPSVQVSPPEPTQVLIKTASGEWQAVQIQETTVTTPTTPTSTPTPAVVTKKVQTGTRKERTLPKIAPAGGGLITLNAAQLASAAQAVQTININGVQVQGVPVTITNAGGQQHLTVQTVPSAGLQLGSVQTQTQTMQIEQTQTLALELQTQPGEKKRRMACTCPNCKDAEKKPGEVGKRKHICHIAGCEKTFRKTSLLRAHVRLHTGERPFVCNWVFCGKRFTRSDELQRHARTHTGDKRFECNKCQKRFMRSDHLTKHYKTHINTKSL", "length": 610, "header": "tr|F1Q4L6-1|F1Q4L6_DANRE Isoform 1 of Transcription factor Sp2 OS=Danio rerio OX=7955 GN=sp2 PE=1 SV=1 CANONICAL=F1Q4L6-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 343, "start_aa": "Thr", "end_pos": 343, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr343", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 386, "start_aa": "Thr", "end_pos": 386, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr386", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Sp2 is a maternally inherited transcription factor required for embryonic development.", "journal": "J. Biol. Chem.", "date": "2010", "authors": "Xie Jianzhen, Yin Haifeng, Nichols Teresa D, Yoder Jeffrey A, Horowitz Jonathan M", "evidence": [ { "database": "UniProtKB", "id": "F1Q4L6", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6" }, { "database": "RefSeq", "id": "NP_001093452", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093452" } ], "reference": [ { "type": "PubMed", "id": "19959469", "url": "https://glygen.org/publication/PubMed/19959469" } ] } ], "pathway": [ { "id": "dre:556835", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556835", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LHR3-1", "protein_name": "Transcription factor Sp2", "gene_name": "Sp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASCSGRCEQTQREPPNHLCSSNATTDSQMSMAATAAVSPSDYLQPAAAATQDSQPSPLALLAATCSKIGPPAVEAAVTPPAPPQPTPRKLVPIKPAPLPLSPCKNSFSILSSKGNILQIQGSQLSASYPGGQFVFAIQNPTLINKGSRSNASIQYQVPQIQGNSSQTIQVQPNLTNQIQIIPGTNQAIITPSTSGHKPVPIKPAPVQKSNTTTTPVQSGANVVKLTGGGGNMTLTLPLNNLVNTSDIGAPAQLLTESPPTPLSKTNKKARKKSLPVSQPSVAVAEQVETVLIETTAENIIQAGNNLLIVQSPGGGQPAVVQQVQVVPPKAEQQQVVQIPQQALRVVQAASATLPTVPQKPSQNFQIQTTEPTPTQVYIRTPSGEVQTVLVQDSPPATAATTSTVSCSSPALRAPHLSGSSKKHSAAILRKERPLPKIAPAGSIISLNAAQLAAAAQAMQTININGVQVQGVPVTITNTGGQQQLTVQNVSGNNLTISGLSPTQIQLQMEQALAGEAQPGEKRRRMACTCPNCKDGEKRSGEQGKKKHVCHIPDCGKTFRKTSLLRAHVRLHTGERPFVCNWFFCGKRFTRSDELQRHARTHTGDKRFECAQCQKRFMRSDHLTKHYKTHLGTKGL", "length": 636 }, "evidence": [ { "id": "MGI:1926162", "url": "https://alliancegenome.org/gene/MGI:1926162#orthology", "database": "AGR" }, { "id": "HGNC:11207", "url": "https://alliancegenome.org/gene/HGNC:11207#orthology", "database": "AGR" }, { "id": "F1Q4L6", "url": "https://omabrowser.org/oma/group/F1Q4L6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q02086-1", "protein_name": "Transcription factor Sp2", "gene_name": "SP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSDPQTSMAATAAVSPSDYLQPAASTTQDSQPSPLALLAATCSKIGPPAVEAAVTPPAPPQPTPRKLVPIKPAPLPLSPGKNSFGILSSKGNILQIQGSQLSASYPGGQLVFAIQNPTMINKGTRSNANIQYQAVPQIQASNSQTIQVQPNLTNQIQIIPGTNQAIITPSPSSHKPVPIKPAPIQKSSTTTTPVQSGANVVKLTGGGGNVTLTLPVNNLVNASDTGAPTQLLTESPPTPLSKTNKKARKKSLPASQPPVAVAEQVETVLIETTADNIIQAGNNLLIVQSPGGGQPAVVQQVQVVPPKAEQQQVVQIPQQALRVVQAASATLPTVPQKPSQNFQIQAAEPTPTQVYIRTPSGEVQTVLVQDSPPATAAATSNTTCSSPASRAPHLSGTSKKHSAAILRKERPLPKIAPAGSIISLNAAQLAAAAQAMQTININGVQVQGVPVTITNTGGQQQLTVQNVSGNNLTISGLSPTQIQLQMEQALAGETQPGEKRRRMACTCPNCKDGEKRSGEQGKKKHVCHIPDCGKTFRKTSLLRAHVRLHTGERPFVCNWFFCGKRFTRSDELQRHARTHTGDKRFECAQCQKRFMRSDHLTKHYKTHLVTKNL", "length": 613 }, "evidence": [ { "id": "MGI:1926162", "url": "https://alliancegenome.org/gene/MGI:1926162#orthology", "database": "AGR" }, { "id": "HGNC:11207", "url": "https://alliancegenome.org/gene/HGNC:11207#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080410-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080410-1#orthology", "database": "AGR" }, { "id": "F1Q4L6", "url": "https://omabrowser.org/oma/group/F1Q4L6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D2H6-1", "protein_name": "Transcription factor Sp2", "gene_name": "Sp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSDPQMSMAATAAVSPSDYLQPAAATTQDSQPSPLALLAATCSKIGPPAVEAAVTPPAPPQPTPRKLVPIKPAPLPLSPCKNSFSILSSKGNILQIQGSQLSTSYPGGQFVFAIQNPTLINKGSRSNASIQYQVPQIQGNSSQTIQVQPSLTNQIQVIPGTNQAITTPSTSGHKPVPIKPAPVQKSSTTTTPVQSGANVVKLTGGGSNMTLTLPLNNLVNTSDIGGPAQLLTESPPTPLSKTNKKARKKSLPVSQPSVAVAEQVETVLIETTADNIIQAGNNLLIVQSPGGGQPAVVQQVQVVPPKAEQQQVVQIPQQALRVVQAASATLPTVPQKPSQNFQIQTTEPTPTQVYIRTPSGEVQTVLVQDSPPATAATTSTVTCNSPALRAPHLSGTSKKHSAAILRKERPLPKIAPAGSIISLNAAQLAAAAQAMQTININGVQVQGVPVTITNTGGQQQLTVQNVSGNNLTISGLSPTQIQLQMEQALAGEAQPGEKRRRMACTCPNCKDGEKRSGEQGKKKHVCHIPDCGKTFRKTSLLRAHVRLHTGERPFVCNWFFCGKRFTRSDELQRHARTHTGDKRFECAQCQKRFMRSDHLTKHYKTHLGTKGL", "length": 612 }, "evidence": [ { "id": "MGI:1926162", "url": "https://alliancegenome.org/gene/MGI:1926162#orthology", "database": "AGR" }, { "id": "HGNC:11207", "url": "https://alliancegenome.org/gene/HGNC:11207#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080410-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080410-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VEW6-1", "protein_name": "Poils au dos", "gene_name": "pad", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAAAGSNVRCINYYDLCRICTDSSDHKTNIYSPEGRAKNLSQKILECLSLQIDEKDRLPKVVCAQCVQLVEQIHGLRATCRNSQTMLNNCLNIRPAPSSDKLYIRDAVDETGKSLSVAQSAPPVPNGAQQSGNLLNSIIQAVNMQPQQQYTITMDNGVQQQQQQHQAMPEVQIKSERQTALEEFIRLKPDIKITPLGKKEPISPAKPQQQHSLQSQTVTPTINPTQLQLQPQLGDQLQPLWQQIQQLQLQQQLQQLTNQLQATTQYSVAQDDTSSSGDSKKPKLNFVLSSPTAPQFTTSMPQFGGSQPQIQLQLMPGSGGVTSAGTVPAQTQLNAAALLSSLAGPQSTTNLLSPNKCFLPITIRDENSDQQIVAHIDTKNLVLPTTYQVQMKLQPQLATADGQPIMQLTPTSIPATLQLTPQTLGNPGSAFQGTTVTQNQFLAPQQPLTQLPNTAQVTSQQIIRSPHTSTTNSQLVIRNVTNIPPTPTTPTSSKKAPTFKTPSPKQKPMPSPKSKTTVGPSSGGSNGTSTNEFKRLITQTKPQPQVKQQQTAGLSASGAPTATSANQAAMQRLSSNTTITKVPKQPASLPAPAPTSNPAKLPMLNKQNITISRISMQTAPKAQSKPSTTSPTPASQPIPVSVPALSQAQPPPLAAQHKKIVRKPPENQDTSGQKVKAARPPQQILPSPQQEGQNATHSGSEAPTTSGLICPTCKREFKKKEHLTQHVKLHAGLRPFKCSEEGCDKTFSRKEHLSRHLVSHSGQKMYTCEVCKKPFSRKDNLNKHRRIHTQTSTETLYCCDVCNKNFATKLHYEKHREMHKKIRPESAAPGATASPAAAPALTHVRSNGQVPNKAVFEIKQERSAQQTQTQQPPAQVMHVVTTQDLAGNTITITQAPDSNMPGSLANYVQLGFSQFQNPSASVAK", "length": 924 }, "evidence": [ { "id": "MGI:1926162", "url": "https://alliancegenome.org/gene/MGI:1926162#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1Q4L6", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1Q4L6", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "F1Q4L6", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "F1Q4L6", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1Q4L6", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1Q4L6", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "F1Q4L6", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 198, "end_pos": 200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1Q4L6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q4L6" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 522, "end_pos": 551, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 343, 386 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 198, "end_pos": 200 }, { "start_pos": 217, "end_pos": 219 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F5N8-1", "uniprot_ac": "E7F5N8", "uniprot_id": "E7F5N8_DANRE", "mass": { "chemical_mass": 118152.0, "monoisotopic_mass": 118152.0 }, "refseq": { "ac": "XP_003201490", "name": "genetic suppressor element 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201490" }, "gene_names": [ { "name": "gse1a", "type": "recommended", "evidence": [ { "id": "E7F5N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5N8" } ] }, { "name": "gse1a", "type": "synonym", "evidence": [ { "id": "XP_003201490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201490" } ] } ], "protein_names": [ { "name": "Genetic suppressor element 1 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F5N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5N8/entry#names_and_taxonomy" } ] }, { "name": "genetic suppressor element 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003201490", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201490" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_003201490.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003201490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201490" } ] } ], "disease": [ { "disease_id": "DOID:10534", "recommended_name": { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "stomach cancer", "description": "A gastrointestinal system cancer that is located_in the stomach." }, "synonyms": [ { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric cancer", "description": "" }, { "id": "DOID:10534", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10534", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "A primary or metastatic malignant neoplasm involving the stomach." }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca lesser curvature - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "GC", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "cancer of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer risk after h. pylori infection", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "gastric cancer, somatic", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumor", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant gastric tumour", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant stomach neoplasm", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumor of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of body of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of greater curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of lesser curve of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant tumour of the stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "stomach cancer", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "Ca body - stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "ca greater curvature of stomach", "description": "" }, { "id": "MONDO:0001056", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0001056", "name": "malignant neoplasm of body of stomach", "description": "" }, { "id": "MIM:613659", "resource": "MIM", "url": "https://www.omim.org/entry/613659", "name": "Gastric cancer", "description": "Gastric cancer" } ], "unlinked_id_list": [], "evidence": [ { "id": "10534", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10534" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F5N8", "url": "https://www.uniprot.org/uniprotkb/E7F5N8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gse1a", "url": "https://www.uniprot.org/uniprotkb/E7F5N8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131121-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000062199", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000062199", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100538211", "url": "https://www.ncbi.nlm.nih.gov/gene/100538211", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042337", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042337", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100538211", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100538211", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PWERFIR", "url": "https://omabrowser.org/oma/group/PWERFIR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3B788", "url": "https://www.orthodb.org/?gene=A0A8M3B788", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F5N8", "url": "https://www.orthodb.org/?gene=E7F5N8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR17608", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17608", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR17608:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR17608:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12540", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12540", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003201490", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201490", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3B788", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B788", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3B788-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3B788-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F5N8", "url": "https://www.uniprot.org/uniprotkb/E7F5N8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F5N8-1", "url": "https://www.uniprot.org/uniprotkb/E7F5N8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131121-4", "url": "https://zfin.org/ZDB-GENE-131121-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSLEPKSLSLGMISAAPCTMATVSPLTASPISGSIAASGSPASQSGFAAALRKLAKQAEEPRGSISSESSHVSSPVTNRISPVSTPKRIAMGTSLAPPTGTPPVVTIAPTKTVNGFWRSEGRQADAGLRLSGQERLAPDRPLPAQEKPSLSLPPYHPFNMTQSALMQDPRLQTHLSRQVPHMLLAGAQEEYVRDGFRPYASAEELRMPLMPLGLNPGTADTLAYFHSGYLPHPSLASYRMEDYYSLSALRSHYYQLPEALHPSAVHLPTPGVFYPPDVTHQALTALHSDRLQMEEELRQQERERQREKERTREIERERQWEQEVQREKEREVEIKKERAREIQPVKAVEKRHLSHEPPASKHLISHSQTHLFPHLQPVKERAKLEDRLTAHRPDKNKEVPQLLSQSGSYSSSGAPSSVSGFSLSTSGLFGKSHRPVETPMMLQRQEEDDRWLARQRVMKVEKTDRHGQEFQQQEKHHSAGRTAEAHREIHRFSSHHNDVPVRDLPPALGAPPPLITPRPAPRHHQHHQLRSPPVASSLWTPVSLLHAPSDRPLSHIHPFSGPSRAPAEGEQPRVSLLKLGQAGAADIRLEMERSEPVMGVGQRRLVSKLDLEEKKRREAREKGYYYDLDDSYDESDEEEVRAHLRRVAQQPPLKLDTSTEKTAFLGLFGLTTLPKRDEVLEMKRRKRRLMLQERSPSPPAVENKRRTPSPLSTRFTADEMNCTAELDDKKHFLSIFNLSHVNHDQRQKKKKISDLLEAIKQKTVTLDTLRYASEAPCSSPPATLSASSHFSQSVNNVHPEPRNHSPENPKTPPDPPPLAPLRNKLSSPSRRAPQQPLARPNNHSQGPNGVKAQVWERINPEEFAQHFHQSVLQSTHTPQQKHRAGVNEQVDPVAHPSPGLQRAVNKLPIRQTNGHSWPVSAHRDSPVVSNDLSAGEGISSDEDEEEESFSPRWKGIESIFTAYEEYIEERSIEHHVLQSECRRLETQHYNLSVTAEQLSHSMRDLLAQKHNLALKRDRMQAELEHFKKCLALPLLHWHRGYYKGPSPR", "length": 1048, "header": "tr|E7F5N8-1|E7F5N8_DANRE Isoform 1 of Genetic suppressor element 1 isoform X1 OS=Danio rerio OX=7955 GN=gse1a PE=4 SV=1 CANONICAL=E7F5N8-1" }, "isoforms": [ { "isoform_ac": "A0A8M3B788-1", "url": "https://www.uniprot.org/uniprotkb/E7F5N8/entry#A0A8M3B788-1", "sequence": { "sequence": "MSLEPKSLSLGMISAAPCTMATVSPLTASPISGSIAASGSPASQSGFAAALRKLAKQAEEPRGSISSESSHVSSPVTNRISPVSTPKRIAMGTSLAPPTGTPPVVTIAPTKTVNGFWRSEGRQADAGLRLSGQERLAPDRPLPAQEKPSLSLPPYHPFNMTQSALMQDPRLQTHLSRQVPHMLLAGAQEEYVRDGFRPYASAEELRMPLMPLGLNPGTADTLAYFHSGYLPHPSLASYRMEDYYSLSALRSHYYQLPEALHPSAVHLPTPGVFYPPDVTHQALTALHSDRLQMEEELRQQERERQREKERTREIERERQWEQEVQREKEREVEIKKERAREIQPVKAVEKRHLSHEPPASKHLISHSQTHLFPHLQPVKERAKLEDRLTAHRPDKNKEVPQLLSQSGSYSSSGAPSSVSGFSLSTSGLFGKSHRPVETPMMLQRQEEDDRWLARQRVMKVEKTDRHGQEFQQQEKHHSAGRTAEAHREIHRFSSHHNDVPVRDLPPALGAPPPLITPRPAPRHHQHHQLRSPPVASSLWTPVSLLHAPSDRPLSHIHPFSGPSRAPAEGEQPRVSLLKLGQAGAADIRLEMERSEPVMGVGQRRLVSKLDLEEKKRREAREKGYYYDLDDSYDESDEEEVRAHLRRVAQQPPLKLDTSTEKTAFLGLFGLTTLPKRDEVLEMKRRKRRLMLQERSPSPPAVENKRRTPSPLSTRFTADEMNCTAELDDKKHFLSIFNLSHVNHDQRQKKKKISDLLEAIKQKTVTLDTLRYASEAPCSSPPATLSASSHFSQSVNNVHPEPRNHSPENPKTPPDPPPLAPLRNKLSSPSRRAPQQPLARPNNHSQGPNGVKAQVWERINPEEFAQHFHQSVLQSTHTPQQKHRGVNEQVDPVAHPSPGLQRAVNKLPIRQTNGHSWPVSAHRDSPVVSNDLSAGEGISSDEDEEEESFSPRWKGIESIFTAYEEYIEERSIEHHVLQSECRRLETQHYNLSVTAEQLSHSMRDLLAQKHNLALKRDRMQAELEHFKKCLALPLLHWHRGYYKGPSPR", "length": 1047, "header": "tr|A0A8M3B788-1|E7F5N8_DANRE Computationally mapped isoform of Genetic suppressor element 1 isoform X1 OS=Danio rerio OX=7955 GN=gse1a PE=4 SV=1 CANONICAL=E7F5N8-1" }, "locus": {} }, { "isoform_ac": "E7F5N8-1", "url": "https://www.uniprot.org/uniprotkb/E7F5N8/entry#E7F5N8-1", "sequence": { "sequence": "MSLEPKSLSLGMISAAPCTMATVSPLTASPISGSIAASGSPASQSGFAAALRKLAKQAEEPRGSISSESSHVSSPVTNRISPVSTPKRIAMGTSLAPPTGTPPVVTIAPTKTVNGFWRSEGRQADAGLRLSGQERLAPDRPLPAQEKPSLSLPPYHPFNMTQSALMQDPRLQTHLSRQVPHMLLAGAQEEYVRDGFRPYASAEELRMPLMPLGLNPGTADTLAYFHSGYLPHPSLASYRMEDYYSLSALRSHYYQLPEALHPSAVHLPTPGVFYPPDVTHQALTALHSDRLQMEEELRQQERERQREKERTREIERERQWEQEVQREKEREVEIKKERAREIQPVKAVEKRHLSHEPPASKHLISHSQTHLFPHLQPVKERAKLEDRLTAHRPDKNKEVPQLLSQSGSYSSSGAPSSVSGFSLSTSGLFGKSHRPVETPMMLQRQEEDDRWLARQRVMKVEKTDRHGQEFQQQEKHHSAGRTAEAHREIHRFSSHHNDVPVRDLPPALGAPPPLITPRPAPRHHQHHQLRSPPVASSLWTPVSLLHAPSDRPLSHIHPFSGPSRAPAEGEQPRVSLLKLGQAGAADIRLEMERSEPVMGVGQRRLVSKLDLEEKKRREAREKGYYYDLDDSYDESDEEEVRAHLRRVAQQPPLKLDTSTEKTAFLGLFGLTTLPKRDEVLEMKRRKRRLMLQERSPSPPAVENKRRTPSPLSTRFTADEMNCTAELDDKKHFLSIFNLSHVNHDQRQKKKKISDLLEAIKQKTVTLDTLRYASEAPCSSPPATLSASSHFSQSVNNVHPEPRNHSPENPKTPPDPPPLAPLRNKLSSPSRRAPQQPLARPNNHSQGPNGVKAQVWERINPEEFAQHFHQSVLQSTHTPQQKHRAGVNEQVDPVAHPSPGLQRAVNKLPIRQTNGHSWPVSAHRDSPVVSNDLSAGEGISSDEDEEEESFSPRWKGIESIFTAYEEYIEERSIEHHVLQSECRRLETQHYNLSVTAEQLSHSMRDLLAQKHNLALKRDRMQAELEHFKKCLALPLLHWHRGYYKGPSPR", "length": 1048, "header": "tr|E7F5N8-1|E7F5N8_DANRE Isoform 1 of Genetic suppressor element 1 isoform X1 OS=Danio rerio OX=7955 GN=gse1a PE=4 SV=1 CANONICAL=E7F5N8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 101, "start_aa": "Thr", "end_pos": 101, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr101", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100538211", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100538211", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AG34-1", "protein_name": "Gse1 coiled-coil protein", "gene_name": "Gse1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFGLKPPLYYLPGMSHEPKSPSIGMLSTATRTTATVNPLTPSPLNGALVPTGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDSGSRGGSSGRERLLVEPPLAQEKAAGPAIPSHLLSTPYPFGLSPSSVVQDSRFQPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTAEDLRMSSLPPLGLDPATAAAYYHPSYLTPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERISSLSAERLQMDEELRREREREREREREADREREKEREREQREKEREKELEREREKERERELERQREQRAREKELLAAKALEPTFLPVAELHGLRGHTTEERPKPSEQLTPTRAEKLKDTGVQAPKPVQHPLHPVPAPHHTVPSLISSHGIFSLPGSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDLGRPLVPTEAEHRPESTRPGPNRHDQGSREPPQHFGGPPPLISPKPQHHTVPTALWNPVSLMDNTLETRRAESHSLHSHPTAFEPSRQAAVPLVKVERVYCTEKAEEPRKREATPLDKYQPPPPPPPPPPREAGGLEPQTFPHGPGPFLAELEKSTQTILGQQRPSLSQTTPFGELTGSLKSGSPYCHTTARGPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPAIQCKRQTPSPRLALSTRYSPDEMNNSPNFEEKRKFLTFFNLTHISAEKRKDKERLVEMLRAMKQRALSAAVADSVATNSSRDSPTISLSEPATQPAPLETDQPAGVPASLSDVPKAVETGRLEQLRPQELLRVQEPAPPSGEKARLSEAPGGKKNLSMLHYLRGAAPKDIPVPLSHSINGKSKPWEPFMAEEFAHQFHESVLQSTQKALQKHKGSSALLSAEQNHKVDTSVHYNIPELQSSSRVPLPQHNGQQEPPAGRKGPPMQEVDQDSEDDSEEEAEEAPRHQWQGIEAIFEAYQEHIEEQNLERQVLQTQCRRLEAQNYSLSLTAEQLSHSMAELRSQKQKMVSERERLQAELDHLRKCLALPTMHWPRGYFKGYPR", "length": 1223 }, "evidence": [ { "id": "HGNC:28979", "url": "https://alliancegenome.org/gene/HGNC:28979#orthology", "database": "AGR" }, { "id": "MGI:1098275", "url": "https://alliancegenome.org/gene/MGI:1098275#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14687-1", "protein_name": "Genetic suppressor element 1", "gene_name": "GSE1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKGMSHEPKSPSLGMLSTATRTTATVNPLTPSPLNGALVPSGSPATSSALSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDAGSRSSSGGRERLIVEPPLPQEKAGGPAIPSHLLSTPYPFGLSPSSVVQDSRFPPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTTDDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSGLSAERLQMDEELRREREREREREREREADREREKEREREREKEREQEKEREREKERERELERQREQRAREKELLAAKALEPSFLPVAELHGLRGHATEERGKPSEQLTPTRAEKLKDAGLQAPKPVQHPLHPVPTPHHTVPSLISNHGIFSLPSSSAATALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDMGRPPVPAEAEHRPESTTRPGPNRHEPGGRDPPQHFGGPPPLISPKPQLHAAPTALWNPVSLMDNTLETRRAESHSLHSHPAAFEPSRQAAVPLVKVERVFCPEKAEEGPRKREPAPLDKYQPPPPPPREGGSLEHQPFLPGPGPFLAELEKSTQTILGQQRASLPQAATFGELSGPLKPGSPYRPPVPRAPDPAYIYDEFLQQRRRLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPTIQSKRQTPSPRLALSTRYSPDEMNNSPNFEEKKKFLTIFNLTHISAEKRKDKERLVEMLRAMKQKALSAAVADSLTNSPRDSPAVSLSEPATQQASLDVEKPVGVAASLSDIPKAAEPGKLEQVRPQELSRVQELAPASGEKARLSEAPGGKKSLSMLHYIRGAAPKDIPVPLSHSTNGKSKPWEPFVAEEFAHQFHESVLQSTQKALQKHKGSVAVLSAEQNHKVDTSVHYNIPELQSSSRAPPPQHNGQQEPPTARKGPPTQELDRDSEEEEEEDDEDGEDEEEVPKRKWQGIEAVFEAYQEHIEEQNLERQVLQTQCRRLEARHYSLSLTAEQLSHSVAELRSQKQKMVSERERLQAELDHLRKCLALPAMHWPRGYLKGYPR", "length": 1217 }, "evidence": [ { "id": "HGNC:28979", "url": "https://alliancegenome.org/gene/HGNC:28979#orthology", "database": "AGR" }, { "id": "MGI:1098275", "url": "https://alliancegenome.org/gene/MGI:1098275#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q1LWL6-1", "protein_name": "Genetic suppressor element 1", "gene_name": "gse1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSHEPKSPSLGMISTATRTTATVSPLTPSPLNGSIVPNVSPASQSAHSGFAAALRKLAKQAEEPRGSSISSESSPVSSPATNHSSPVSTPKRGPMGPVIVPPGGHSVPSTPPVVTIAPTKTVNGLWRSESRSVREVESVPHGVSRDRLSSEAASAQEKGGPTVPAHLIGNPYPFGLTPASVMQDSRFQPLNLPRQMPHAVPTASVPEEYLRGFRPYATAEELRMPSLPLGLDPATAAAAAAYYHPGYLPHPSFSHYRMDDPFCLSALRSPFYQLPAGGALPPLHPSAVHMHLPGVRYPGDLSHPSLSSLQSERLSERLQMEDELRQREREREREREKEREREAEREKEREREREREKELEREREREREREREKEREREREMERQKERAAREKAAESHYLTELHGLRGAPDDRAKPDRITSNRPEKTKESILTTPKPIQPGIHQSLNSTHHPVPSLSSAHGLYLGPGGAGPTSLTVATMLQRTEEERWLARQRKLRQEKEDRQYQVSEFRQQVLEQHLDLGRQGEIPDMNVEGHRPVPNHHEPSSRDRDRDRDSHPLLGAPPPLISPKHQHKDHAPPPPTTLWNPAALIETSTDSRRTLHDPPSLGHYDISRLPLPPSKHERHYNSEKLEEGSRKRDSLDKYPPIRPSGFSEPNTFLAELEKSTQSFLNQQRAPLSLSGPYGELSAGFKSSGPLKNLQGHSRLAPDTTLVYDEFLQQHRRAVSKLDLEERRRREAREKGYYYELDDSYDESDEEEVRAHLRRVSEQPPLKLDDSTEKVEFLEMFDLTTLAHREEMMEVKRKKRRRMLRERSPSPPTVQNKRPTPTPLLTRFTPEDMNNSPELEDKKRFLTIFSLNHITQQQRRDNERVEELLQAIKQKSVTLDTIRHNPHPLCRSPAAHSSDQSSQSPVQSEELLNGWPLSPSPSVSIPQPSADPLSISDQHRPLSDPPKPKDSSLPPALPDKCRANDSLPGKSSSLLNSLRQPPFAKESSVSVNGKTKPWENFIAEEFAQQFHESVLQSTQKALQKSKGGALVVLEQNHAVDSSVHYNIPELQSTPGRSKPHPHPPSSQPNGQHCPPQPSRQELSAEESEEEEEEDDTEEDEPSTSRWQGIEAIFEAYQEYAEEQSIERQVLHSQCRRLEAHHYNLSLTAEQLSHSMGELMAQKQKLAAERENLQAELEHFKKCLTLPQSPWSRAHFKGYPPR", "length": 1203 }, "evidence": [ { "id": "HGNC:28979", "url": "https://alliancegenome.org/gene/HGNC:28979#orthology", "database": "AGR" }, { "id": "MGI:1098275", "url": "https://alliancegenome.org/gene/MGI:1098275#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3U3C9-1", "protein_name": "Genetic suppressor element 1", "gene_name": "Gse1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKGMSHEPKSPSIGMLSTATRTTATVNPLTPSPLNGALVPTGSPATSSTLSAQAAPSSSFAAALRKLAKQAEEPRGSSLSSESSPVSSPATNHSSPASTPKRVPMGPIIVPPGGHSVPSTPPVVTIAPTKTVNGVWRSESRQDSGSRGSSSGRERLLVEPPLAQEKAAGPAIPSHLLSTPYPFGLSPGSVVQDSRFQPLNLQRPVHHVVPPSTVTEDYLRSFRPYHTAEDLRMSSLPPLGLDPATAAAYYHPSYLAPHPFPHPAFRMDDSYCLSALRSPFYPIPTPGSLPPLHPSAMHLHLSGVRYPPELSHSSLAALHSERMSSLSAERLQMDEELRREREREREREREADREREKEREREQREKEREKELEREREKERERELERQREQRAREKELLAAKALEPTTFLPVAELHGLRGHSTEERPKPSEQLTPTRAEKLKDVGLQAPKPVQHPLHPVPAPHHTVPSLISSHGIFSLPGSSATTALLIQRTNEEEKWLARQRRLRQEKEDRQSQVSEFRQQVLEQHLDLGRPLVPTEAEHRPESTRPGTNRHEQGSREPPQHFGGPPPLISPKPQQHTVPTALWNPVSLMDNALETRRAESHSLHSHPTAFEPSRQAAVPLVKVERVYCSEKAEEPRKREATPLDKYQPPPPPPPPREAGSLEPQTFPHGPGPFLTELEKSTQTILGQQRPSLSQATSFGELSGPLKPGSPYCHPTARGPDPAYIYDEFLQQRRKLVSKLDLEERRRREAQEKGYYYDLDDSYDESDEEEVRAHLRCVAEQPPLKLDTSSEKLEFLQLFGLTTQQQKEELVAQKRRKRRRMLRERSPSPPAVQCKRQTPSPRLALSTRYSPDEMNNSPNFEEKRKFLTFFNLTHISAEKRKDKERLVEMLRAMKQRALSAADSVTNSSRDSPPVSLSEPATQPAPLETDQPVGVPASLSDVPKTTETGRLEQLRPQELLRVQEPAPPSGEKARLSEAPGGKKSLSMLHYLRGAAPKDIPVPLSHSINGKSKPWEPFVAEEFAHQFHESVLQSTQKALQKHKGNSALLSAEQSHKVDTAIHYNIPELQSSSRVPLPQHNGQQEPPMGRKGPPMQEADQDSEEDSEEDSEEEAEEAPRRQWQGIEAIFEAYQEHIEEQNLERQVLQTQCRRLEAQNYSLSLTAEQLSHSMAELRSQKQKMVSERERLQAELDHLRKCLALPTMHWPRGYFKGYPR", "length": 1213 }, "evidence": [ { "id": "HGNC:28979", "url": "https://alliancegenome.org/gene/HGNC:28979#orthology", "database": "AGR" }, { "id": "MGI:1098275", "url": "https://alliancegenome.org/gene/MGI:1098275#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-4#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 721, "end_pos": 723, "annotation": "n_glycosylation_sequon" }, { "start_pos": 737, "end_pos": 739, "annotation": "n_glycosylation_sequon" }, { "start_pos": 803, "end_pos": 805, "annotation": "n_glycosylation_sequon" }, { "start_pos": 842, "end_pos": 844, "annotation": "n_glycosylation_sequon" }, { "start_pos": 990, "end_pos": 992, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F5N8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5N8" }, { "id": "PF12540", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12540" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Genetic suppressor element-like", "eco_id": "ECO_0000259", "start_pos": 602, "end_pos": 739, "start_aa": "Gln", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 101 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 159, "end_pos": 161 }, { "start_pos": 721, "end_pos": 723 }, { "start_pos": 737, "end_pos": 739 }, { "start_pos": 803, "end_pos": 805 }, { "start_pos": 842, "end_pos": 844 }, { "start_pos": 990, "end_pos": 992 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E9QGF9-1", "uniprot_ac": "E9QGF9", "uniprot_id": "E9QGF9_DANRE", "mass": { "chemical_mass": 154296.0, "monoisotopic_mass": 154296.0 }, "refseq": { "ac": "XP_005165688", "name": "rho GTPase-activating protein 31 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165688" }, "gene_names": [ { "name": "arhgap31", "type": "recommended", "evidence": [ { "id": "E9QGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QGF9" } ] }, { "name": "arhgap31", "type": "synonym", "evidence": [ { "id": "XP_005165688", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165688" } ] } ], "protein_names": [ { "name": "Rho GTPase-activating protein 31 isoform X1", "type": "synonym", "evidence": [ { "id": "E9QGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QGF9/entry#names_and_taxonomy" } ] }, { "name": "rho GTPase-activating protein 31 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005165688", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165688" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005165688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165688" } ] } ], "disease": [ { "disease_id": "DOID:0060227", "recommended_name": { "id": "DOID:0060227", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060227", "name": "Adams-Oliver syndrome", "description": "A syndrome characterized by defects of the scalp (aplasia cutis congenita), abnormalities of the fingers, toes, arms and legs." }, "synonyms": [ { "id": "DOID:0060227", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060227", "name": "Adams Oliver syndrome", "description": "" }, { "id": "MONDO:0013635", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013635", "name": "Adams-Oliver syndrome 2", "description": "Any Adams-Oliver syndrome in which the cause of the disease is a mutation in the DOCK6 gene." }, { "id": "MONDO:0013635", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013635", "name": "Adams-Oliver syndrome 2", "description": "" }, { "id": "MONDO:0013635", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013635", "name": "Adams-Oliver syndrome caused by mutation in DOCK6", "description": "" }, { "id": "MONDO:0013635", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013635", "name": "Adams-Oliver syndrome type 2", "description": "" }, { "id": "MONDO:0013635", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013635", "name": "DOCK6 Adams-Oliver syndrome", "description": "" }, { "id": "MONDO:0013635", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013635", "name": "AOS2", "description": "" }, { "id": "MONDO:0014124", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014124", "name": "Adams-Oliver syndrome 4", "description": "Any Adams-Oliver syndrome in which the cause of the disease is a mutation in the EOGT gene." }, { "id": "MONDO:0014124", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014124", "name": "Adams-Oliver syndrome 4", "description": "" }, { "id": "MONDO:0014124", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014124", "name": "Adams-Oliver syndrome caused by mutation in EOGT", "description": "" }, { "id": "MONDO:0014124", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014124", "name": "Adams-Oliver syndrome type 4", "description": "" }, { "id": "MONDO:0014124", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014124", "name": "EOGT Adams-Oliver syndrome", "description": "" }, { "id": "MONDO:0014124", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014124", "name": "AOS4", "description": "" }, { "id": "MONDO:0014459", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014459", "name": "Adams-Oliver syndrome 5", "description": "Any Adams-Oliver syndrome in which the cause of the disease is a mutation in the NOTCH1 gene." }, { "id": "MONDO:0014459", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014459", "name": "AOS5", "description": "" }, { "id": "MONDO:0014459", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014459", "name": "Adams-Oliver syndrome 5", "description": "" }, { "id": "MONDO:0014459", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014459", "name": "Adams-Oliver syndrome caused by mutation in NOTCH1", "description": "" }, { "id": "MONDO:0014459", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014459", "name": "Adams-Oliver syndrome caused by mutation in Notch1", "description": "" }, { "id": "MONDO:0014459", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014459", "name": "Adams-Oliver syndrome type 5", "description": "" }, { "id": "MONDO:0024506", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024506", "name": "Adams-Oliver syndrome 1", "description": "Any Adams-Oliver syndrome in which the cause of the disease is a mutation in the ARHGAP31 gene." }, { "id": "MONDO:0024506", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024506", "name": "AOS1", "description": "" }, { "id": "MONDO:0024506", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024506", "name": "ARHGAP31 Adams-Oliver syndrome", "description": "" }, { "id": "MONDO:0024506", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024506", "name": "Adams-Oliver syndrome 1", "description": "" }, { "id": "MONDO:0024506", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024506", "name": "Adams-Oliver syndrome caused by mutation in ARHGAP31", "description": "" }, { "id": "MONDO:0024506", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024506", "name": "AOS", "description": "" }, { "id": "MIM:614219", "resource": "MIM", "url": "https://www.omim.org/entry/614219", "name": "Adams-Oliver syndrome 2", "description": "Adams-Oliver syndrome 2" }, { "id": "MIM:615297", "resource": "MIM", "url": "https://www.omim.org/entry/615297", "name": "Adams-Oliver syndrome 4", "description": "Adams-Oliver syndrome 4" }, { "id": "MIM:616028", "resource": "MIM", "url": "https://www.omim.org/entry/616028", "name": "Adams-Oliver syndrome 5", "description": "Adams-Oliver syndrome 5" }, { "id": "MIM:100300", "resource": "MIM", "url": "https://www.omim.org/entry/100300", "name": "Adams-Oliver syndrome 1", "description": "Adams-Oliver syndrome 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060227", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060227" } ] }, { "disease_id": "DOID:3393", "recommended_name": { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary artery disease", "description": "An artery disease that is characterized by plaque building up along the inner walls of the arteries of the heart resulting in a narrowing of the arteries and a reduced blood supply to the cardiac muscles." }, "synonyms": [ { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "CHD", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Coronary disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary arteriosclerosis", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "coronary heart disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "Ischemic Heart Disease", "description": "" }, { "id": "DOID:3393", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3393", "name": "myocardial ischemia", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, 3", "description": "" }, { "id": "MONDO:0010331", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010331", "name": "coronary heart disease, susceptibility to, type 3", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the CX3CR1 gene." }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "CX3CR1 coronary artery disease", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease caused by mutation in CX3CR1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary artery disease, resistance to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, 1", "description": "" }, { "id": "MONDO:0011817", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011817", "name": "coronary heart disease, susceptibility to, type 1", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012009", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012009", "name": "coronary heart disease, susceptibility to, type 2", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, 4", "description": "" }, { "id": "MONDO:0012010", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012010", "name": "coronary heart disease, susceptibility to, type 4", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the MEF2A gene." }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "MEF2A coronary artery disease", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease caused by mutation in MEF2A", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "coronary artery disease, autosomal dominant, type 1", "description": "" }, { "id": "MONDO:0012011", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012011", "name": "ADCAD1", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "Any coronary artery disease in which the cause of the disease is a mutation in the LRP6 gene." }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "LRP6 coronary artery disease", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease caused by mutation in LRP6", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant type 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "coronary artery disease, autosomal dominant, 2", "description": "" }, { "id": "MONDO:0012586", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012586", "name": "ADCAD2", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "CHDS8", "description": "" }, { "id": "MONDO:0012628", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012628", "name": "coronary heart disease, susceptibility to, 8", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "CHDS9", "description": "" }, { "id": "MONDO:0012788", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012788", "name": "coronary heart disease, susceptibility to, 9", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "Any complete hydatidiform mole in which the cause of the disease is a mutation in the KHDC3L gene." }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "KHDC3L complete hydatidiform mole", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "complete hydatidiform mole caused by mutation in KHDC3L", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform Mole, recurrent, type 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "hydatidiform mole, recurrent, 2", "description": "" }, { "id": "MONDO:0013671", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0013671", "name": "HYDM2", "description": "" }, { "id": "MIM:608320", "resource": "MIM", "url": "https://www.omim.org/entry/608320", "name": "Coronary artery disease, autosomal dominant, 1", "description": "Coronary artery disease, autosomal dominant, 1" }, { "id": "MIM:610947", "resource": "MIM", "url": "https://www.omim.org/entry/610947", "name": "Coronary artery disease, autosomal dominant, 2", "description": "Coronary artery disease, autosomal dominant, 2" }, { "id": "MIM:614293", "resource": "MIM", "url": "https://www.omim.org/entry/614293", "name": "Hydatidiform mole, recurrent, 2", "description": "Hydatidiform mole, recurrent, 2" } ], "unlinked_id_list": [ "DOID:11840" ], "evidence": [ { "id": "3393", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3393" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QGF9", "url": "https://www.uniprot.org/uniprotkb/E9QGF9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "arhgap31", "url": "https://www.uniprot.org/uniprotkb/E9QGF9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100922-256", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100922-256", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000059472", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000059472", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd04384", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04384", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "101885883", "url": "https://www.ncbi.nlm.nih.gov/gene/101885883", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000198", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000198", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008936", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008936", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051576", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051576", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885883", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885883", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMIKTCQ", "url": "https://omabrowser.org/oma/group/YMIKTCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3BA15", "url": "https://www.orthodb.org/?gene=A0A8M3BA15", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E9QGF9", "url": "https://www.orthodb.org/?gene=E9QGF9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15729", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15729", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15729:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15729:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00620", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00620", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-8980692", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8980692", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9013149", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013149", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9013420", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013420", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005165688", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005165688", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3BA15", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BA15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3BA15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BA15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QGF9", "url": "https://www.uniprot.org/uniprotkb/E9QGF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QGF9-1", "url": "https://www.uniprot.org/uniprotkb/E9QGF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100922-256", "url": "https://zfin.org/ZDB-GENE-100922-256", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKNKAAKLKSKRKGTDNAFGCDLSEHLQSSGQDVPHVLKTCAEFIEKHGIVDGIYRLSGITSNIQKLRQEFSSELCPDLTKEVYLQDIHCVGSLCKLYFRELPNPLLTYELYSKFTHAVSVKEEQEQLRNIRSAIKELPESHFRTLEYLTKHLAYLATLSHQTNMHARNLALVWAPNLLRSKEVEVPSCNGDIAFLEVRVQQSVVEFILNHTEQIFNLEFQPSKARDGPSMACGEKYATLPASTQCGPMKLMSLEEAQARSLSPNHPVMKERQRENSLPDTSTAAMYHTVIDLSDSRRKFSGKSKKWKSIFSLGRSVIDSKGKLSRNGSVFMRAQNSSEKTAIRPSKSMDSLCSFQAPDEDKAAAEGANGMFIPIHKSRTLGSDINYLNKKDPKWDLESQTASGGSLNEKREGASNASSSSSSPSSSLSPLQKSLPEQLKVFKGDERGGCQPTSPKNRRMLYSGSANNGSSRPSFPGSLFPLESSPRHQRKALNISEPFAVSVPLRVSAVINSNSTPCRAPGKERDRGLGGLFRPSKEAGPLEGHRRESMGAAGLCGAGNFSFTDWETGLAGRAIGSGHRENSSGGSGCSIYSNSSSFPMENEEQSGEGDFTDAIAMATTKSKDAEVRELIATVENFQPQASSETKAIGEELETTSTKQEMAKLDKLELIDKVPSSGMHDKVSITEVKTTNMPNDGVKPCITKINGNQGNLKLSAQARRSSLPSNTVSSKGLFIDLTKNVMFDHPGATTFNSVMKHMPERLLSCDGDWNYLDSDSDRTEHKARNIITTSLQLSPFLHLKETDILQDAEPCIEEEPKIDLCEKDGTSKSDSKDNTSVSVKLDLHTDEESLRTSDICEKENKKVSDEPRKLDLAGRIKGNLERLSTCLNEKHLTLEIQDDVDACGSNLDQVEPWEDLCSAQQWVTSPLHSPKLEDLFPTQREILPCQKVHCQVLDKPNADELPNSRNPEAKEPAALDEIAPTQTEAAVTAELGNSDFPTGKKNADTDVACFAQITAHFDRDKFKFEGAKDDIKLEIPQVKQLKTFNDPEETTGMQNMSKAKQKRSQRFHRQTSHEFCIMEKSQGSGKPKLRPCSLNLDLGHQGFRDISNSQYLKSGKQWMTPEAKDGSSSLELELFLSGPKAPMRRNSAPVSVSSVRTAFMIKTCQAKAVPVIPPKIQYSHIPHTLPERKNAEKSTDQVNKSTPEKKPTKSKLGKASSLFPLQKVCREDRQSTEPPSGIQRHKSMNSATCNENYKPTSIPDLPVLRRKRSANGDTFMDRPRPERSSLLQRSSFRNRPRPQSLILFSPPFPIMDYPSVGDDNKQALSPIKAETSPFDAYANELAENLKTTEGVTLRNKMTLPKSGQRLETSTSCFYQPQRRSMIFDNRSNRQIE", "length": 1391, "header": "tr|E9QGF9-1|E9QGF9_DANRE Isoform 1 of Rho GTPase-activating protein 31 isoform X1 OS=Danio rerio OX=7955 GN=arhgap31 PE=4 SV=2 CANONICAL=E9QGF9-1" }, "isoforms": [ { "isoform_ac": "A0A8M3BA15-1", "url": "https://www.uniprot.org/uniprotkb/E9QGF9/entry#A0A8M3BA15-1", "sequence": { "sequence": "MKNKAAKLKSKRKGTDNAFGCDLSEHLQSSGQDVPHVLKTCAEFIEKHGIVDGIYRLSGITSNIQKLRQEFSSELCPDLTKEVYLQDIHCVGSLCKLYFRELPNPLLTYELYSKFTHAVSVKEEQEQLRNIRSAIKELPESHFRTLEYLTKHLAYLATLSHQTNMHARNLALVWAPNLLRSKEVEVPSCNGDIAFLEVRVQQSVVEFILNHTEQIFNLEFQPSKARDGPSMACGEKYATLPASTQCGPMKLMSLEEAQARSLSPNHPVMKERQRENSLPDTSTAAMYHTVIDLSDSRKFSGKSKKWKSIFSLGRSVIDSKGKLSRNGSVFMRAQNSSEKTAIRPSKSMDSLCSFQAPDEDKAAAEGANGMFIPIHKSRTLGSDINYLNKKDPKWDLESQTASGGSLNEKREGASNASSSSSSPSSSLSPLQKSLPEQLKVFKGDERGGCQPTSPKNRRMLYSGSANNGSSRPSFPGSLFPLESSPRHQRKALNISEPFAVSVPLRVSAVINSNSTPCRAPGKERDRGLGGLFRPSKEAGPLEGHRRESMGAAGLCGAGNFSFTDWETGLAGRAIGSGHRENSSGGSGCSIYSNSSSFPMENEEQSGEGDFTDAIAMATTKSKDAEVRELIATVENFQPQASSETKAIGEELETTSTKQEMAKLDKLELIDKVPSSGMHDKVSITEVKTTNMPNDGVKPCITKINGNQGNLKLSAQARRSSLPSNTVSSKGLFIDLTKNVMFDHPGATTFNSVMKHMPERLLSCDGDWNYLDSDSDRTEHKARNIITTSLQLSPFLHLKETDILQDAEPCIEEEPKIDLCEKDGTSKSDSKDNTSVSVKLDLHTDEESLRTSDICEKENKKVSDEPRKLDLAGRIKGNLERLSTCLNEKHLTLEIQDDVDACGSNLDQVEPWEDLCSAQQWVTSPLHSPKLEDLFPTQREILPCQKVHCQVLDKPNADELPNSRNPEAKEPAALDEIAPTQTEAAVTAELGNSDFPTGKKNADTDVACFAQITAHFDRDKFKFEGAKDDIKLEIPQVKQLKTFNDPEETTGMQNMSKAKQKRSQRFHRQTSHEFCIMEKSQGSGKPKLRPCSLNLDLGHQGFRDISNSQYLKSGKQWMTPEAKDGSSSLELELFLSGPKAPMRRNSAPVSVSSVRTAFMIKTCQAKAVPVIPPKIQYSHIPHTLPERKNAEKSTDQVNKSTPEKKPTKSKLGKASSLFPLQKVCREDRQSTEPPSGIQRHKSMNSATCNENYKPTSIPDLPVLRRKRSANGDTFMDRPRPERSSLLQRSSFRNRPRPQSLILFSPPFPIMDYPSVGDDNKQALSPIKAETSPFDAYANELAENLKTTEGVTLRNKMTLPKSGQRLETSTSCFYQPQRRSMIFDNRSNRQIE", "length": 1390, "header": "tr|A0A8M3BA15-1|E9QGF9_DANRE Computationally mapped isoform of Rho GTPase-activating protein 31 isoform X1 OS=Danio rerio OX=7955 GN=arhgap31 PE=4 SV=1 CANONICAL=E9QGF9-1" }, "locus": {} }, { "isoform_ac": "E9QGF9-1", "url": "https://www.uniprot.org/uniprotkb/E9QGF9/entry#E9QGF9-1", "sequence": { "sequence": "MKNKAAKLKSKRKGTDNAFGCDLSEHLQSSGQDVPHVLKTCAEFIEKHGIVDGIYRLSGITSNIQKLRQEFSSELCPDLTKEVYLQDIHCVGSLCKLYFRELPNPLLTYELYSKFTHAVSVKEEQEQLRNIRSAIKELPESHFRTLEYLTKHLAYLATLSHQTNMHARNLALVWAPNLLRSKEVEVPSCNGDIAFLEVRVQQSVVEFILNHTEQIFNLEFQPSKARDGPSMACGEKYATLPASTQCGPMKLMSLEEAQARSLSPNHPVMKERQRENSLPDTSTAAMYHTVIDLSDSRRKFSGKSKKWKSIFSLGRSVIDSKGKLSRNGSVFMRAQNSSEKTAIRPSKSMDSLCSFQAPDEDKAAAEGANGMFIPIHKSRTLGSDINYLNKKDPKWDLESQTASGGSLNEKREGASNASSSSSSPSSSLSPLQKSLPEQLKVFKGDERGGCQPTSPKNRRMLYSGSANNGSSRPSFPGSLFPLESSPRHQRKALNISEPFAVSVPLRVSAVINSNSTPCRAPGKERDRGLGGLFRPSKEAGPLEGHRRESMGAAGLCGAGNFSFTDWETGLAGRAIGSGHRENSSGGSGCSIYSNSSSFPMENEEQSGEGDFTDAIAMATTKSKDAEVRELIATVENFQPQASSETKAIGEELETTSTKQEMAKLDKLELIDKVPSSGMHDKVSITEVKTTNMPNDGVKPCITKINGNQGNLKLSAQARRSSLPSNTVSSKGLFIDLTKNVMFDHPGATTFNSVMKHMPERLLSCDGDWNYLDSDSDRTEHKARNIITTSLQLSPFLHLKETDILQDAEPCIEEEPKIDLCEKDGTSKSDSKDNTSVSVKLDLHTDEESLRTSDICEKENKKVSDEPRKLDLAGRIKGNLERLSTCLNEKHLTLEIQDDVDACGSNLDQVEPWEDLCSAQQWVTSPLHSPKLEDLFPTQREILPCQKVHCQVLDKPNADELPNSRNPEAKEPAALDEIAPTQTEAAVTAELGNSDFPTGKKNADTDVACFAQITAHFDRDKFKFEGAKDDIKLEIPQVKQLKTFNDPEETTGMQNMSKAKQKRSQRFHRQTSHEFCIMEKSQGSGKPKLRPCSLNLDLGHQGFRDISNSQYLKSGKQWMTPEAKDGSSSLELELFLSGPKAPMRRNSAPVSVSSVRTAFMIKTCQAKAVPVIPPKIQYSHIPHTLPERKNAEKSTDQVNKSTPEKKPTKSKLGKASSLFPLQKVCREDRQSTEPPSGIQRHKSMNSATCNENYKPTSIPDLPVLRRKRSANGDTFMDRPRPERSSLLQRSSFRNRPRPQSLILFSPPFPIMDYPSVGDDNKQALSPIKAETSPFDAYANELAENLKTTEGVTLRNKMTLPKSGQRLETSTSCFYQPQRRSMIFDNRSNRQIE", "length": 1391, "header": "tr|E9QGF9-1|E9QGF9_DANRE Isoform 1 of Rho GTPase-activating protein 31 isoform X1 OS=Danio rerio OX=7955 GN=arhgap31 PE=4 SV=2 CANONICAL=E9QGF9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885883", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885883", "resource": "KEGG Pathway" }, { "id": "R-DRE-8980692", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8980692", "resource": "Reactome", "description": "RHOA GTPase cycle" }, { "id": "R-DRE-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-DRE-9013149", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013149", "resource": "Reactome", "description": "RAC1 GTPase cycle" }, { "id": "R-DRE-9013420", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013420", "resource": "Reactome", "description": "RHOU GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "A6X8Z5-1", "protein_name": "Rho GTPase-activating protein 31", "gene_name": "Arhgap31", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKNKGAKQKLKRKGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGITSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHRPEEGQLARIQNVILELPPPHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKKIEATICNGDAAFLAVRVQQVVIEFILNHADQIFNGGAPGALQQDESRTITKSLTLPALSLPMKLVSLEEAQARSLATNHPARKERRENSLPEIVPPPFHTVLELPDNKRKLSSKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVEKATIRPAKSMDSLCSVPVEGKENKGNFSRTVTTGGFFIPATKMHASSTGSSCDLSKEGEWGQEGMPAGAEGGCEVGGQIRPLPEQLKVFRPIGDPESEQSAPKLLGMFYTSSDSPGKSVFTSSLFQMEPSPRHQRKALNISEPFAVSVPLRVSAVISTNSTPCRTPPKELQSLSSLEEFSFQGSESGGWPEEEKPLGAESFPGSVTKKAATEDTKPEPEVPGRAECSQSPPLDPGTQVEKKTLHVSLGSQVSKEAEKRPKAEKVMEESQGASQPKPSTPQESLGAGTEPLILHEMDEEDLAQALIWPEIQQELKIIESEEEFSSLPPAAQKTSPIPESSPAPFPFPEAPGSLPSSSAPREVWTRDAANQSIQEAAILTDREKLEPVCSLLESESQQELSPDPASLAPLEMLLFEKVSSPARIEIGGPRNLSPPLTPAPPPPTPLEEEPEVLLSKEGPDREDAARDSRTDVYTEQPTPKESPGIPTPCQREEAIASPNEKQNARHAVPENKGPGLPSPTKEVDIIPQEEGGAPHSAQEPSDCDEDDTVTDPAQHGLEMVEPWEEPQWVTSPLHSPTLKEVQESQTQGSQGHRLERRLCHRPSLRQSHSLDSKTTGNSHWTLEAPFSSSCANLETERNYEPLQPPAARTKIAGLEEKALKAFREFSGLKGLEVLPSQKGPSGIQPKPVETNFMGLAEGKEQEPQLELSNRQMKHSDVPGPDSSKESSPRAQDSTLPGEHPLQLQLKNTECGPSKGKHRPSSLNLDSATPIADLFRLENGAPFSSPGIELSELGDTKVTWMSSSHCKAAPWNSQDTQDLDIVAHTLTGRRNSAPVSVSAVRTSFMVKMCQAKAVPVIPPKIQYTQIPQPLPSQSTGEGGAQPLERSQEEPGSTPEIPQKSTKDDSPSSLGSPEEEQPKQETGASASRRQASITSCMYEGSSCSPEPSASTLASTQDAVVQCRKRTSETEPSGDNLLSSKLERASGGPKAFHRSRPGRPQSLILFPIMDHLPSSPTVIDSKVLLSPIRSPTQTVSPGLLCGELAENTWITPEGVTLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE", "length": 1425 }, "evidence": [ { "id": "MGI:1333857", "url": "https://alliancegenome.org/gene/MGI:1333857#orthology", "database": "AGR" }, { "id": "HGNC:29216", "url": "https://alliancegenome.org/gene/HGNC:29216#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100922-256", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100922-256#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A987-1", "protein_name": "Rho GTPase activating protein 31", "gene_name": "Arhgap31", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKNKGAKQKLKRKGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGVTSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNVIQELPPPHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKKIEATICNGDAAFLAVRVQQVVIEFILNHADQIFNGGAPGALQQDESRTITKSLTLPALSLPMKLVSLEEAQARSLATNHPARKERRENSLPEIVPSMGTPFHTVLELPDNKRKLSSKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVEKATIRPAKSMDSLCSVPVEGKENKGNFNRTVTTGGFFIPATKMHASSTGSSCDLSKEGEWSQEGMPAGAEGGCEVGGQIRPLPEQLKVFRPIGDPESEQSAPKLLGMFYTSSDSPGKSVFTSSLFQMEPSPRHQRKALNISEPFAVSVPLRVSAVISTNSTPCRTPPKELQSLSSLEEFSFQGSESGGWPEEEKPLGAEPFPGSVPKKAATEDTKPEHEAPGRAECNQSLPLDPGTPLEKKTLDISLGSQLSKEPEKWPNAEKAMEESQGASQTKLSTPQESPRARTKPVLLHEMDEDDLAQALIWPEIQQELKIIESEEEFSSLPPPAQKTSPMTESSPAPFPSPEAPESLPSSSAPLEVWTRDSANQSIQETAILTNREKLEPVCSLLESESEQAVSPDPSTLAPLEILLFEKVSSPARIEIGGPGNLSPPLPPAPPPPTPLEEEPQVLLSHEGPDREDASRDSRTDLYTEQPNSEDSPGIPRLCQREEAIASPNEKQDAKQAVPESKDPGLPSPTKEVEVIPQEEGDASHSAQEPSDCDEDDTVIDTAQHGLEMVEPWEEPQWVTSPLHSPTLKEIQESQTQGSQGHRLERRLRHRPSLRQSHSLDSKTTGQSHWALEAPFSSSCASLETERNYEPLQTPSARIKIAGLEEKALKAFREFSGLKGLEVLPSQKGSSGIQPKPVETNFISLTEGKEQGPQLEFSNPQIKHNDVPGPDSSEGSSPGAQDSTSPGEHPLKLQLKSTECGPSKGKHRPSSLNLDSAIPIADLFRVENGASFSSPGIELSELGDTKVIWMSSSQGKAAPWSSQDTQDLGIVAHALTGRRNSAPVSVSAVRTSFMVKMCQAKAVPVIPPKIQYTQIPQPLPSQNTGEGGAQPPERNQEEPGSTPETPQKPTKDDSPSSLGSPEEEQPKQEQGASASRRKASTTSCVAEGSFCSAEPGPSTLVSSQDAMGQCRKRTSETEPSEDNLLSSKLERASGGPKPTHRPRPGRPQSLILFPIMDHLPSSPTVIDSKVLLSPIRSPSQTVSPGLLCGELAENTWVTPEGVTLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE", "length": 1428 }, "evidence": [ { "id": "MGI:1333857", "url": "https://alliancegenome.org/gene/MGI:1333857#orthology", "database": "AGR" }, { "id": "HGNC:29216", "url": "https://alliancegenome.org/gene/HGNC:29216#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2M1Z3-1", "protein_name": "Rho GTPase-activating protein 31", "gene_name": "ARHGAP31", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKNKGAKQKLKRKGAASAFGCDLTEYLESSGQDVPYVLKSCAEFIETHGIVDGIYRLSGVTSNIQRLRQEFGSDQCPDLTREVYLQDIHCVGSLCKLYFRELPNPLLTYELYEKFTEAVSHCPEEGQLARIQNVIQELPPSHYRTLEYLIRHLAHIASFSSKTNMHARNLALVWAPNLLRSKEIEATGCNGDAAFLAVRVQQVVIEFILNHVDQIFNNGAPGSLENDENRPIMKSLTLPALSLPMKLVSLEEAQARSLATNHPARKERRENSLPEIVPPMGTLFHTVLELPDNKRKLSSKSKKWKSIFNLGRSGSDSKSKLSRNGSVFVRGQRLSVEKATIRPAKSMDSLCSVPVEGKETKGNFNRTVTTGGFFIPATKMHSTGTGSSCDLTKQEGEWGQEGMPPGAEGGFDVSSDRSHLQGAQARPPPEQLKVFRPVEDPESEQTAPKMLGMFYTSNDSPSKSVFTSSLFQMEPSPRNQRKALNISEPFAVSVPLRVSAVISTNSTPCRTPPKELQSLSSLEEFSFHGSESGGWPEEEKPLGAETSAASVPKKAGLEDAKAVPEAPGTVECSKGLSQEPGAHLEEKKTPESSLSSQHLNELEKRPNPEKVVEEGREAGEMESSTLQESPRARAEAVLLHEMDEDDLANALIWPEIQQELKIIESEEELSSLPPPALKTSPIQPILESSLGPFIPSEPPGSLPCGSFPAPVSTPLEVWTRDPANQSTQGASTAASREKPEPEQGLHPDLASLAPLEIVPFEKASPQATVEVGGPGNLSPPLPPAPPPPTPLEESTPVLLSKGGPEREDSSRKLRTDLYIDQLKSQDSPEISSLCQGEEATPRHSDKQNSKNAASEGKGCGFPSPTREVEIVSQEEEDVTHSVQEPSDCDEDDTVTDIAQHGLEMVEPWEEPQWVTSPLHSPTLKDAHKAQVQGLQGHQLEKRLSHRPSLRQSHSLDSKPTVKSQWTLEVPSSSSCANLETERNSDPLQPQAPRREITGWDEKALRSFREFSGLKGAEAPPNQKGPSGVQPNPAETSPISLAEGKELGTHLGHSSPQIRQGGVPGPESSKESSPSVQDSTSPGEHPAKLQLKSTECGPPKGKNRPSSLNLDPAIPIADLFWFENVASFSSPGMQVSEPGDPKVTWMTSSYCKADPWRVYSQDPQDLDIVAHALTGRRNSAPVSVSAVRTSFMVKMCQARAVPVIPPKIQYTQIPQPLPSQSSGENGVQPLERSQEGPSSTSGTTQKPAKDDSPSSLESSKEEKPKQDPGAIKSSPVDATAPCMCEGPTLSPEPGSSNLLSTQDAVVQCRKRMSETEPSGDNLLSSKLERPSGGSKPFHRSRPGRPQSLILFSPPFPIMDHLPPSSTVTDSKVLLSPIRSPTQTVSPGLLCGELAENTWVTPEGVTLRNKMTIPKNGQRLETSTSCFYQPQRRSVILDGRSGRQIE", "length": 1444 }, "evidence": [ { "id": "MGI:1333857", "url": "https://alliancegenome.org/gene/MGI:1333857#orthology", "database": "AGR" }, { "id": "HGNC:29216", "url": "https://alliancegenome.org/gene/HGNC:29216#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100922-256", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100922-256#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "E9QGF9", "url": "https://www.uniprot.org/uniprotkb/E9QGF9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E9QGF9", "url": "https://www.uniprot.org/uniprotkb/E9QGF9" } ], "pmid": "" }, { "name": "small GTPase-mediated signal transduction", "id": "GO:0007264", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007264", "evidence": [ { "database": "UniProtKB", "id": "E9QGF9", "url": "https://www.uniprot.org/uniprotkb/E9QGF9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "lamellipodium", "id": "GO:0030027", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030027", "evidence": [ { "database": "UniProtKB", "id": "E9QGF9", "url": "https://www.uniprot.org/uniprotkb/E9QGF9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1054, "end_pos": 1056, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1198, "end_pos": 1200, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1384, "end_pos": 1386, "annotation": "n_glycosylation_sequon" }, { "start_pos": 210, "end_pos": 212, "annotation": "n_glycosylation_sequon" }, { "start_pos": 327, "end_pos": 329, "annotation": "n_glycosylation_sequon" }, { "start_pos": 336, "end_pos": 338, "annotation": "n_glycosylation_sequon" }, { "start_pos": 416, "end_pos": 418, "annotation": "n_glycosylation_sequon" }, { "start_pos": 468, "end_pos": 470, "annotation": "n_glycosylation_sequon" }, { "start_pos": 494, "end_pos": 496, "annotation": "n_glycosylation_sequon" }, { "start_pos": 514, "end_pos": 516, "annotation": "n_glycosylation_sequon" }, { "start_pos": 560, "end_pos": 562, "annotation": "n_glycosylation_sequon" }, { "start_pos": 582, "end_pos": 584, "annotation": "n_glycosylation_sequon" }, { "start_pos": 594, "end_pos": 596, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 835, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E9QGF9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QGF9" }, { "id": "PS50238", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50238" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rho-GAP", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 216, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1054, "end_pos": 1056 }, { "start_pos": 1198, "end_pos": 1200 }, { "start_pos": 1384, "end_pos": 1386 }, { "start_pos": 210, "end_pos": 212 }, { "start_pos": 327, "end_pos": 329 }, { "start_pos": 336, "end_pos": 338 }, { "start_pos": 416, "end_pos": 418 }, { "start_pos": 468, "end_pos": 470 }, { "start_pos": 494, "end_pos": 496 }, { "start_pos": 514, "end_pos": 516 }, { "start_pos": 560, "end_pos": 562 }, { "start_pos": 582, "end_pos": 584 }, { "start_pos": 594, "end_pos": 596 }, { "start_pos": 833, "end_pos": 835 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FCF0-1", "uniprot_ac": "E7FCF0", "uniprot_id": "E7FCF0_DANRE", "mass": { "chemical_mass": 53205.0, "monoisotopic_mass": 53205.0 }, "refseq": { "ac": "XP_001338149", "name": "divergent protein kinase domain 1A isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338149" }, "gene_names": [ { "name": "dipk1ab", "type": "recommended", "evidence": [ { "id": "E7FCF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCF0" } ] }, { "name": "dipk1ab", "type": "synonym", "evidence": [ { "id": "XP_001338149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338149" } ] } ], "protein_names": [ { "name": "Divergent protein kinase domain 1A isoform X1", "type": "synonym", "evidence": [ { "id": "E7FCF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCF0/entry#names_and_taxonomy" } ] }, { "name": "divergent protein kinase domain 1A isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001338149", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338149" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133181) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_001338149.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001338149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338149" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FCF0", "url": "https://www.uniprot.org/uniprotkb/E7FCF0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dipk1ab", "url": "https://www.uniprot.org/uniprotkb/E7FCF0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131126-27", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131126-27", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000061362", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000061362", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "797682", "url": "https://www.ncbi.nlm.nih.gov/gene/797682", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022049", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022049", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029244", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029244", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:797682", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797682", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YMRIKYL", "url": "https://omabrowser.org/oma/group/YMRIKYL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3BAE7", "url": "https://www.orthodb.org/?gene=A0A8M3BAE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YYW0", "url": "https://www.orthodb.org/?gene=A0A8M6YYW0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FCF0", "url": "https://www.orthodb.org/?gene=E7FCF0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21093", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21093", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21093:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21093:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12260", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12260", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14875", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14875", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001338149", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338149", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M3BAE7", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BAE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3BAE7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3BAE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YYW0", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYW0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YYW0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YYW0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JUV4", "url": "https://www.uniprot.org/uniprotkb/A0AC58JUV4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JUV4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JUV4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FCF0", "url": "https://www.uniprot.org/uniprotkb/E7FCF0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FCF0-1", "url": "https://www.uniprot.org/uniprotkb/E7FCF0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131126-27", "url": "https://zfin.org/ZDB-GENE-131126-27", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLLIAREVRRLRSITLFIIRSPYGEKHPGLVSAVKCGVSIMARGLIPWIWLKRPVYIQARFSYLHMKFLFFSWLAVFVGSWVVYVEYSSYTELCRGHECKNTICDKFQKGVIDGSACNSLCEKDTLYLGKCLSAKPSNQVYSGSWGDMEGIIKCQMKEDPHYDLGFELEPRKESASFSRPTKGTSMQKFKEMVFNHLKAKVGDQANLADLLTLVLGVADSNKDGEISLSEAHSAWALLQLNEFLLSVVLQEREHTPRLLGFCGDLYVMEKVPYVPLYGVSLPWMVELWIPASLRRSIDQWATPSWPRKAKIAIGLFELVEDVFHGTFGSFLMCDVSAAGFGYTERHDIKVVDARQIVPEVGFQEVMRERRCEEDTDCLYGRDCFTSCDLTKHRCTTEVTQPNLAKVCSTLKDYILYGAPSDIKDELDKQLYACIALKGASEQMEMEHSLILNNLKTLLWKKISHTKDS", "length": 468, "header": "tr|E7FCF0-1|E7FCF0_DANRE Isoform 1 of Divergent protein kinase domain 1A isoform X1 OS=Danio rerio OX=7955 GN=dipk1ab PE=3 SV=1 CANONICAL=E7FCF0-1" }, "isoforms": [ { "isoform_ac": "A0A8M3BAE7-1", "url": "https://www.uniprot.org/uniprotkb/E7FCF0/entry#A0A8M3BAE7-1", "sequence": { "sequence": "MTTSATAAQDTAWSRIMETLRSSRRWSWIQSARFSYLHMKFLFFSWLAVFVGSWVVYVEYSSYTELCRGHECKNTICDKFQKGVIDGSACNSLCEKDTLYLGKCLSAKPSNQVYSGSWGDMEGIIKCQMKEDPHYDLGFELEPRKESASFSRPTKGTSMQKFKEMVFNHLKAKVGDQANLADLLTLVLGVADSNKDGEISLSEAHSAWALLQLNEFLLSVVLQEREHTPRLLGFCGDLYVMEKVPYVPLYGVSLPWMVELWIPASLRRSIDQWATPSWPRKAKIAIGLFELVEDVFHGTFGSFLMCDVSAAGFGYTERHDIKVVDARQIVPEVGFQEVMRERRCEEDTDCLYGRDCFTSCDLTKHRCTTEVTQPNLAKVCSTLKDYILYGAPSDIKDELDKQLYACIALKGASEQMEMEHSLILNNLKTLLWKKISHTKDS", "length": 441, "header": "tr|A0A8M3BAE7-1|E7FCF0_DANRE Computationally mapped isoform of Divergent protein kinase domain 1A isoform X1 OS=Danio rerio OX=7955 GN=dipk1ab PE=3 SV=1 CANONICAL=E7FCF0-1" }, "locus": {} }, { "isoform_ac": "A0A8M6YYW0-1", "url": "https://www.uniprot.org/uniprotkb/E7FCF0/entry#A0A8M6YYW0-1", "sequence": { "sequence": "MARNTLACAVKCGVSIMARGLIPWIWLKRPVYIQARFSYLHMKFLFFSWLAVFVGSWVVYVEYSSYTELCRGHECKNTICDKFQKGVIDGSACNSLCEKDTLYLGKCLSAKPSNQVYSGSWGDMEGIIKCQMKEDPHYDLGFELEPRKESASFSRPTKGTSMQKFKEMVFNHLKAKVGDQANLADLLTLVLGVADSNKDGEISLSEAHSAWALLQLNEFLLSVVLQEREHTPRLLGFCGDLYVMEKVPYVPLYGVSLPWMVELWIPASLRRSIDQWATPSWPRKAKIAIGLFELVEDVFHGTFGSFLMCDVSAAGFGYTERHDIKVVDARQIVPEVGFQEVMRERRCEEDTDCLYGRDCFTSCDLTKHRCTTEVTQPNLAKVCSTLKDYILYGAPSDIKDELDKQLYACIALKGASEQMEMEHSLILNNLKTLLWKKISHTKDS", "length": 444, "header": "tr|A0A8M6YYW0-1|E7FCF0_DANRE Computationally mapped isoform of Divergent protein kinase domain 1A isoform X1 OS=Danio rerio OX=7955 GN=dipk1ab PE=3 SV=1 CANONICAL=E7FCF0-1" }, "locus": {} }, { "isoform_ac": "A0AC58JUV4-1", "url": "https://www.uniprot.org/uniprotkb/E7FCF0/entry#A0AC58JUV4-1", "sequence": { "sequence": "MKFLFFSWLAVFVGSWVVYVEYSSYTELCRGHECKNTICDKFQKGVIDGSACNSLCEKDTLYLGKCLSAKPSNQVYSGSWGDMEGIIKCQMKEDPHYDLGFELEPRKESASFSRPTKGTSMQKFKEMVFNHLKAKVGDQANLADLLTLVLGVADSNKDGEISLSEAHSAWALLQLNEFLLSVVLQEREHTPRLLGFCGDLYVMEKVPYVPLYGVSLPWMVELWIPASLRRSIDQWATPSWPRKAKIAIGLFELVEDVFHGTFGSFLMCDVSAAGFGYTERHDIKVVDARQIVPEVGFQEVMRERRCEEDTDCLYGRDCFTSCDLTKHRCTTEVTQPNLAKVCSTLKDYILYGAPSDIKDELDKQLYACIALKGASEQMEMEHSLILNNLKTLLWKKISHTKDS", "length": 403, "header": "tr|A0AC58JUV4-1|A0AC58JUV4_DANRE Computationally mapped isoform of Divergent protein kinase domain 1A isoform X4 OS=Danio rerio OX=7955 GN=dipk1ab PE=3 SV=1 CANONICAL=E7FCF0-1" }, "locus": {} }, { "isoform_ac": "E7FCF0-1", "url": "https://www.uniprot.org/uniprotkb/E7FCF0/entry#E7FCF0-1", "sequence": { "sequence": "MLLIAREVRRLRSITLFIIRSPYGEKHPGLVSAVKCGVSIMARGLIPWIWLKRPVYIQARFSYLHMKFLFFSWLAVFVGSWVVYVEYSSYTELCRGHECKNTICDKFQKGVIDGSACNSLCEKDTLYLGKCLSAKPSNQVYSGSWGDMEGIIKCQMKEDPHYDLGFELEPRKESASFSRPTKGTSMQKFKEMVFNHLKAKVGDQANLADLLTLVLGVADSNKDGEISLSEAHSAWALLQLNEFLLSVVLQEREHTPRLLGFCGDLYVMEKVPYVPLYGVSLPWMVELWIPASLRRSIDQWATPSWPRKAKIAIGLFELVEDVFHGTFGSFLMCDVSAAGFGYTERHDIKVVDARQIVPEVGFQEVMRERRCEEDTDCLYGRDCFTSCDLTKHRCTTEVTQPNLAKVCSTLKDYILYGAPSDIKDELDKQLYACIALKGASEQMEMEHSLILNNLKTLLWKKISHTKDS", "length": 468, "header": "tr|E7FCF0-1|E7FCF0_DANRE Isoform 1 of Divergent protein kinase domain 1A isoform X1 OS=Danio rerio OX=7955 GN=dipk1ab PE=3 SV=1 CANONICAL=E7FCF0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:797682", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:797682", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PQJ3-1", "protein_name": "Divergent protein kinase domain 1A", "gene_name": "FAM69A", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARRLFAGAWLRKPHHAQVRFSYMRMKYLFISWLVVFIGSWVMYVQYSTYTELCRGHDCRKIICDKYKTGVIDGSACSSLCAKETLYFGKCLSTKPNNQMYLGIWGNLQGVIKCQMEEAARLDFGTDPEPRKEIILFDKPTRGTTVEKFKEMVYSFFKAKLGEQGNLSELVNIILSFADGNKDGRVSLPEAKSAWALLQLDEFLLMVMLQDKEHTPKLMGFCGDLYVIERVEYTSLYGISLPWMIELLIPSGFRRSMDQWFTPSWPRKAKIAIGLLEFVEDIFHGPYGNFLMCDTSARNLGYNDKYDLKMMDMRKIVPEMNLKEMIKDRPCESDMDCVYGTDCRTLCDQSKMRCTTEVIQPNLAKVCQLLKDYLLRGAPSDIHEELEKQLYLCIALKVSANQMEMEHSLILNNLKTLLWKKISHTTDS", "length": 428 }, "evidence": [ { "id": "E7FCF0", "url": "https://omabrowser.org/oma/group/E7FCF0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S4G2-1", "protein_name": "Divergent protein kinase domain 1A", "gene_name": "DIPK1A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARSLCPGAWLRKPRYLQARFSYVRMKYLFFSWLVVFVGSWIIYVQYSAYTELCRGKDCKKIICDKYKTGVIDGPACNSLCVTETLYFGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQALHLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDKDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVIELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNDKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQPNLAKACQLLKDYLLRGAPSEIREELEKQLYSCIALKVTAKQMEMEHSLILNNLKTLLWKKISYTNDS", "length": 428 }, "evidence": [ { "id": "E7FCF0", "url": "https://omabrowser.org/oma/group/E7FCF0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3HED0-1", "protein_name": "Divergent protein kinase domain 1A isoform X1", "gene_name": "Dipk1a", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRVKYLFFSWLVVFVGSWVIYVQYSTYTELCRGKDCKKIICDKYKTGVIDGPACSSLCVTETLYLGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQTLHLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDRDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVIELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNEKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQPNLAKACQLLKDYLLHGAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWKKISYTNDS", "length": 405 }, "evidence": [ { "id": "E7FCF0", "url": "https://omabrowser.org/oma/group/E7FCF0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q1RLQ5-1", "protein_name": "Divergent protein kinase domain 1A", "gene_name": "dipk1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MARGLFSRAWLSKTHHFQARLSYIRVKYLFLTWLAVFVSSWVVYVQYSTYTELCRGRECKSIICDKYSKGIIDGSACSSLCEESKLYFGRCLSTKPNNQVYTGSWGDQDGVIKCQLSDVLHYELGEELEPKKEITLFEKPTRGTSVEKFKEMVASHLKAKVGEQANLSNLVSLILSVADSNKDGHISLPEAKSAWALLQLNEVLLAVVLQGREHTPKLLGFCGDLYVVERVPHAPLFGITLPWPMDLWIPAGMRRSMDQWFTPSWPRKAKIFIGLLELIEDIFHGTFGSFLMCDMRASSFGYTDRHDLRLVDGRRVVAEEAFKQAMILQRCKDHEDCVYGADCRTSCDLSEQRCTAEVAQPNLARACGAMKDYLLRGAPFHLQEELEKQLYACMALKGSAEQMEMEHSLILNNLKTLLWKQISHTTDS", "length": 428 }, "evidence": [ { "id": "HGNC:32213", "url": "https://alliancegenome.org/gene/HGNC:32213#orthology", "database": "AGR" }, { "id": "MGI:1914516", "url": "https://alliancegenome.org/gene/MGI:1914516#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5T7M9-1", "protein_name": "Divergent protein kinase domain 1A", "gene_name": "DIPK1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARSLCPGAWLRKPYYLQARFSYVRMKYLFFSWLVVFVGSWIIYVQYSTYTELCRGKDCKKIICDKYKTGVIDGPACNSLCVTETLYFGKCLSTKPNNQMYLGIWDNLPGVVKCQMEQALHLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDKDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVIELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNDKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDQSTMKCTSEVIQPNLAKACQLLKDYLLRGAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWKKISYTNDS", "length": 428 }, "evidence": [ { "id": "HGNC:32213", "url": "https://alliancegenome.org/gene/HGNC:32213#orthology", "database": "AGR" }, { "id": "MGI:1914516", "url": "https://alliancegenome.org/gene/MGI:1914516#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131126-27", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131126-27#orthology", "database": "AGR" }, { "id": "E7FCF0", "url": "https://omabrowser.org/oma/group/E7FCF0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D6I7-1", "protein_name": "Divergent protein kinase domain 1A", "gene_name": "Dipk1a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARSLCAGAWLRKPHYLQARLSYMRVKYLFFSWLVVFVGSWIIYVQYSTYTELCRGKDCKKIICDKYKTGVIDGPACNSLCVTETLYFGKCLSNKPSNQMYLGVWDNLPGVVKCQMEQALHLDFGTELEPRKEIVLFDKPTRGTTVQKFKEMVYSLFKAKLGDQGNLSELVNLILTVADGDRDGQVSLGEAKSAWALLQLNEFLLMVILQDKEHTPKLMGFCGDLYVMESVEYTSLYGISLPWVMELFIPSGFRRSMDQLFTPSWPRKAKIAIGLLEFVEDVFHGPYGNFLMCDTSAKNLGYNEKYDLKMVDMRKIVPETNLKELIKDRHCESDLDCVYGTDCRTSCDLSTMKCTSEVIQPNLAKACQLLKDYLLHGAPSEIREELEKQLYSCIALKVTANQMEMEHSLILNNLKTLLWKKISYTNDS", "length": 428 }, "evidence": [ { "id": "HGNC:32213", "url": "https://alliancegenome.org/gene/HGNC:32213#orthology", "database": "AGR" }, { "id": "MGI:1914516", "url": "https://alliancegenome.org/gene/MGI:1914516#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131126-27", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131126-27#orthology", "database": "AGR" }, { "id": "E7FCF0", "url": "https://omabrowser.org/oma/group/E7FCF0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "E7FCF0", "url": "https://www.uniprot.org/uniprotkb/E7FCF0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "kinase activity", "id": "GO:0016301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016301", "evidence": [ { "database": "UniProtKB", "id": "E7FCF0", "url": "https://www.uniprot.org/uniprotkb/E7FCF0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FCF0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCF0" }, { "id": "SM01299", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM01299" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FAM69 N-terminal", "eco_id": "ECO_0000259", "start_pos": 59, "end_pos": 217, "start_aa": "Ala", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F2X3-1", "uniprot_ac": "E7F2X3", "uniprot_id": "E7F2X3_DANRE", "mass": { "chemical_mass": 109310.0, "monoisotopic_mass": 109310.0 }, "refseq": { "ac": "XP_009291649", "name": "integrator complex subunit 4 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291649" }, "gene_names": [ { "name": "ints4", "type": "recommended", "evidence": [ { "id": "E7F2X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2X3" } ] }, { "name": "ints4", "type": "synonym", "evidence": [ { "id": "XP_009291649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291649" } ] } ], "protein_names": [ { "name": "Integrator complex subunit 4", "type": "recommended", "evidence": [ { "id": "E7F2X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2X3/entry#names_and_taxonomy" } ] }, { "name": "integrator complex subunit 4 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_009291649", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291649" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133193) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009291649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291649" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F2X3", "url": "https://www.uniprot.org/uniprotkb/E7F2X3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ints4", "url": "https://www.uniprot.org/uniprotkb/E7F2X3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120215-81", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-81", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000102953", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000102953", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "564681", "url": "https://www.ncbi.nlm.nih.gov/gene/564681", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057412", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057412", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564681", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564681", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GNRHPDY", "url": "https://omabrowser.org/oma/group/GNRHPDY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YW13", "url": "https://www.orthodb.org/?gene=A0A8M6YW13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F2X3", "url": "https://www.orthodb.org/?gene=E7F2X3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20938", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20938", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20938:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20938:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24493", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24493", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25458", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25458", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_009291649", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009291649", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YW13", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YW13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YW13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YW13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F2X3", "url": "https://www.uniprot.org/uniprotkb/E7F2X3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F2X3-1", "url": "https://www.uniprot.org/uniprotkb/E7F2X3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120215-81", "url": "https://zfin.org/ZDB-GENE-120215-81", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAAHLKKRVYEEFSKVSQQVTLEEVPSKKLRLTKPSKSAALHIDLCKATNPTDALQYLLSFARKPVEAESVEGVVRILLEHYYKESDNSVRLKIASLLGLLSKTQGFASDCIVDDAINTLNTEKSHQVLAQLLDTLLIIGTQLPDKTAVIQRLIDVACKHLSSTYFGVRNKCLQLLGCLGTVDKPLSKETDTGAGAGAQTSAVRDVLSLISDYFQDQDPRVRTAAIKAMLQLHERGMKIQQTIYNQACKLLSDDYEQVRSAAVQMVWVLSQLYPESIVPIPSSNEEIRLVDDSFGKICHMVSDGSWVVRVQAAKLLGSMHQVSPHFLEQTLDKKLMSDLRRKRTAHERAKELYASGEFSSGRRWADDAPKEKVDTSGVNLIDSGACGAFVHGLEDEMYEVRIAAVEALCSLAQSSRSFAEKCLDFLVDMFNDEIEEVRLQSIHVLRQISTHITLREDQLDTVLAVLEDSSRDIREALHELLCYTNVSTKECIQLALLELLKNLSKYPTDRNSVWKCLKFLGARHPTLVLPIVPELLSTHPYFDTPEPDMDDPAYIAVLVLVFNAAQSCPTMPALFSDHTFRHYAYLRDSLSHLVPHLRLPGRKQTASSGVEASGVGSGSLESAKNFLQDSLVRVSALQNLETPGAQDLLEFTIRDLLRLGELQTELAGSADFCATYLRCQLLLTKALQEKLWTMAVPLCLKQNAKVSTATRQILDETYKLEFLYSGLETQQIATIHNVRLQAKALQLILTARSKRGVDRVLGVCEKFLQDVESFQRLFMTELPHFQDSFVEKLLELMPRLTACKPLDLVKILQTTLRQSRCIHLKLPEQIHRASATIIEPTGESDNPLRFTSGLVVALDIDATLEHVQDPQTTVKVQVLYPDGQSHIIHPKPGDFRTPGPGRVRLITQVYLSHSAWTEPCQIEVRLLLAYSSSSSKLSSSKPAWNESMDGLPTSESSIEGTIHLSKPVKVFIMPKPARR", "length": 979, "header": "tr|E7F2X3-1|E7F2X3_DANRE Isoform 1 of Integrator complex subunit 4 OS=Danio rerio OX=7955 GN=ints4 PE=1 SV=1 CANONICAL=E7F2X3-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YW13-1", "url": "https://www.uniprot.org/uniprotkb/E7F2X3/entry#A0A8M6YW13-1", "sequence": { "sequence": "MAAHLKKRVYEEFSKVSQVTLEEVPSKKLRLTKPSKSAALHIDLCKATNPTDALQYLLSFARKPVEAESVEGVVRILLEHYYKESDNSVRLKIASLLGLLSKTQGFASDCIVDDAINTLNTEKSHQVLAQLLDTLLIIGTQLPDKTAVIQRLIDVACKHLSSTYFGVRNKCLQLLGCLGTVDKPLSKETDTGAGAGAQTSAVRDVLSLISDYFQDQDPRVRTAAIKAMLQLHERGMKIQQTIYNQACKLLSDDYEQVRSAAVQMVWVLSQLYPESIVPIPSSNEEIRLVDDSFGKICHMVSDGSWVVRVQAAKLLGSMHQVSPHFLEQTLDKKLMSDLRRKRTAHERAKELYASGEFSSGRRWADDAPKEKVDTSGVNLIDSGACGAFVHGLEDEMYEVRIAAVEALCSLAQSSRSFAEKCLDFLVDMFNDEIEEVRLQSIHVLRQISTHITLREDQLDTVLAVLEDSSRDIREALHELLCYTNVSTKECIQLALLELLKNLSKYPTDRNSVWKCLKFLGARHPTLVLPIVPELLSTHPYFDTPEPDMDDPAYIAVLVLVFNAAQSCPTMPALFSDHTFRHYAYLRDSLSHLVPHLRLPGRKQTASSGVEASGVGSGSLESAKNFLQDSLVRVSALQNLETPGAQDLLEFTIRDLLRLGELQTELAGSADFCATYLRCQLLLTKALQEKLWTMAVPLCLKQNAKVSTATRQILDETYKLEFLYSGLETQQIATIHNVRLQAKALQLILTARSKRGVDRVLGVCEKFLQDVESFQRLFMTELPHFQDSFVEKLLELMPRLTACKPLDLVKILQTTLRQSRCIHLKLPEQIHRASATIIEPTGESDNPLRFTSGLVVALDIDATLEHVQDPQTTVKVQVLYPDGQSHIIHPKPGDFRTPGPGRVRLITQVYLSHSAWTEPCQIEVRLLLAYSSSSSKLSSSKPAWNESMDGLPTSESSIEGTIHLSKPVKVFIMPKPARR", "length": 978, "header": "tr|A0A8M6YW13-1|E7F2X3_DANRE Computationally mapped isoform of Integrator complex subunit 4 OS=Danio rerio OX=7955 GN=ints4 PE=1 SV=1 CANONICAL=E7F2X3-1" }, "locus": {} }, { "isoform_ac": "E7F2X3-1", "url": "https://www.uniprot.org/uniprotkb/E7F2X3/entry#E7F2X3-1", "sequence": { "sequence": "MAAHLKKRVYEEFSKVSQQVTLEEVPSKKLRLTKPSKSAALHIDLCKATNPTDALQYLLSFARKPVEAESVEGVVRILLEHYYKESDNSVRLKIASLLGLLSKTQGFASDCIVDDAINTLNTEKSHQVLAQLLDTLLIIGTQLPDKTAVIQRLIDVACKHLSSTYFGVRNKCLQLLGCLGTVDKPLSKETDTGAGAGAQTSAVRDVLSLISDYFQDQDPRVRTAAIKAMLQLHERGMKIQQTIYNQACKLLSDDYEQVRSAAVQMVWVLSQLYPESIVPIPSSNEEIRLVDDSFGKICHMVSDGSWVVRVQAAKLLGSMHQVSPHFLEQTLDKKLMSDLRRKRTAHERAKELYASGEFSSGRRWADDAPKEKVDTSGVNLIDSGACGAFVHGLEDEMYEVRIAAVEALCSLAQSSRSFAEKCLDFLVDMFNDEIEEVRLQSIHVLRQISTHITLREDQLDTVLAVLEDSSRDIREALHELLCYTNVSTKECIQLALLELLKNLSKYPTDRNSVWKCLKFLGARHPTLVLPIVPELLSTHPYFDTPEPDMDDPAYIAVLVLVFNAAQSCPTMPALFSDHTFRHYAYLRDSLSHLVPHLRLPGRKQTASSGVEASGVGSGSLESAKNFLQDSLVRVSALQNLETPGAQDLLEFTIRDLLRLGELQTELAGSADFCATYLRCQLLLTKALQEKLWTMAVPLCLKQNAKVSTATRQILDETYKLEFLYSGLETQQIATIHNVRLQAKALQLILTARSKRGVDRVLGVCEKFLQDVESFQRLFMTELPHFQDSFVEKLLELMPRLTACKPLDLVKILQTTLRQSRCIHLKLPEQIHRASATIIEPTGESDNPLRFTSGLVVALDIDATLEHVQDPQTTVKVQVLYPDGQSHIIHPKPGDFRTPGPGRVRLITQVYLSHSAWTEPCQIEVRLLLAYSSSSSKLSSSKPAWNESMDGLPTSESSIEGTIHLSKPVKVFIMPKPARR", "length": 979, "header": "tr|E7F2X3-1|E7F2X3_DANRE Isoform 1 of Integrator complex subunit 4 OS=Danio rerio OX=7955 GN=ints4 PE=1 SV=1 CANONICAL=E7F2X3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:564681", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564681", "resource": "KEGG Pathway" }, { "id": "R-DRE-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XEA1-1", "protein_name": "Integrator complex subunit 4", "gene_name": "INTS4", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAHLKKRVYEEFTKVVQVSAEGSELCRVTPQQHEDLSAKKLRLTKPSKSAALHVDLCKATSPADALQYLLQFARKPVEVESVEGVVRILLEHYYKENDASVRLKIASLLGLLSKTAGFSPDCIMDDAINTLQNEKSHQVLAQLLDTLLVIGTKLTENPSVRMRLVEVACKHLTDSSHGVRNKCLQLIGCLGPVEKGVAKEAESQAAKDVQKIIGDHFNDQDPRVRTAAIKAMLQLHERGLKLQQAIYGQACKLLADDYEQVRSAAVQLIWVLSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMQQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEIDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRESIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTPEPDMDDPAYIAVLVLIFNAAKSCPTMPALFSDHTFRHYAYLRDSLSHLVPPLRLPGRKLVSSPVSPSITPHEDPSQQFLHQSLERVYNLQHLDPQGIQELLEFTIRDLQRLGELQSELAGMADFTATYLQCQLLLIKVLFSRALQEKLWNVAAPLYLKQNALASAAAKQILEETYKMEFMYSGVESRQVVIIHHMRLQAKALQLIVTARTTRGVEPLFGMCEKFLQEVDSFQRCFISELPQMQGSFVDKLLDLMPRLVTSKPSEVVKILQTTLRQSTFLHLPLPERLHRASANIIEPTGESDNPLRFTSGLVVALDVDATLEHVQDPQGTVKVQVLYPDGQAQLIHPKPADFRNPGPGRHRLITQVYLSHTAWTEPCQIEVRLLLAYNSNKSKAATKIAKSTWNESLEALPQPENGIEGTIPFSKPVKVYIMPKPARR", "length": 987 }, "evidence": [ { "id": "E7F2X3", "url": "https://omabrowser.org/oma/group/E7F2X3/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0M8R3-1", "protein_name": "Integrator complex subunit 4", "gene_name": "Ints4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAHLKKRVYEEFTKVVQQQQEEITTKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRLKIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGSKLPENQATQVRLVDVACKHLTDTSHGVRNKCLQLLGNLGSLEKSVTKDTEGLTARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEIDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTLRHYAYLRDSLSHLVPALRLPGRKLVSSAVPSNITPHEDPSQQFLQQSLERVYSVQHLDPQGAQELLEFTIRDLQRLGELQSELAGVADFSATYLQCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVVIIHHMRLQARALQLLVTARTTRGVDPLFGMCEKFLQEVDFFQRCFIADLPHLQDSFVDKLLDLMPRLMASKPGEVIKILQTMLRQSTFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNSVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLLTQVYLSHTAWTEPCQVEVRLLLAYNSGARIPKSPWLEGSEMSPQVETSIEGTIPFTQRCQNSTRHRKDAYHGK", "length": 967 }, "evidence": [ { "id": "HGNC:25048", "url": "https://alliancegenome.org/gene/HGNC:25048#orthology", "database": "AGR" }, { "id": "MGI:1917164", "url": "https://alliancegenome.org/gene/MGI:1917164#orthology", "database": "AGR" }, { "id": "E7F2X3", "url": "https://omabrowser.org/oma/group/E7F2X3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3I5D5-1", "protein_name": "Integrator complex subunit 4", "gene_name": "Ints4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAHLKKRVYEEFTKVVQQQQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRLKIASLLGLLSKTSGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGSKLPENQATQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSLEKSVTKDAEGLTARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEIDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTFRHYAYLRDSLSHLVPALRLPGRKLVSSTVSSNITPHEDPSQQFLQQSLDRVYSVQHLDPQGAQELLEFTIRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVVIIHHMRLQAKALQLIVTARTTRGVDPLFGMCEKFLQEVDFFQRCFIADLPHLQDSFVDKLLDLMPRLMASKPVEVIKILQTMLRQSTFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNSVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLITQVYLSHTAWTEPCQVEVRLLLAYNSGARIPKSPWIEGGEMSSHVENSIEGTIPFSKPVKVYIMPKPARR", "length": 964 }, "evidence": [ { "id": "E7F2X3", "url": "https://omabrowser.org/oma/group/E7F2X3/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q8CIM8-1", "protein_name": "Integrator complex subunit 4", "gene_name": "Ints4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAHLKKRVYEEFTKVVQQQQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRLKIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGSKLPENQATQVRLVDVACKHLTDTSHGVRNKCLQLLGNLGSLEKSVTKDTEGSAARDVQKIIGDHFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEIDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTLRHYAYLRDSLSHLVPALRLPGRKLVSSTVPSNITPHEDPSQQFLQQSLERVYSVQHLDPQGAQELLEFTIRDLQRLGELQSELAGVADFSATYLQCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVVIIQHMRLQAKALQLIVTARTTRGVDPLFGMCEKFLQEVDFFQRCFIADLPHLQDSFVDKLLDLMPRLMASKPVEVIKILQTMLRQSTFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLLTQVYLSHTAWTEPCQVEVRLLLAYNSGARIPKSPWLEGSEMSPQVETSIEGTIPFSKPVKVYIMPKPARR", "length": 964 }, "evidence": [ { "id": "HGNC:25048", "url": "https://alliancegenome.org/gene/HGNC:25048#orthology", "database": "AGR" }, { "id": "MGI:1917164", "url": "https://alliancegenome.org/gene/MGI:1917164#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-81", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-81#orthology", "database": "AGR" }, { "id": "E7F2X3", "url": "https://omabrowser.org/oma/group/E7F2X3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96HW7-1", "protein_name": "Integrator complex subunit 4", "gene_name": "INTS4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAHLKKRVYEEFTKVVQPQEEIATKKLRLTKPSKSAALHIDLCKATSPADALQYLLQFARKPVEAESVEGVVRILLEHYYKENDPSVRLKIASLLGLLSKTAGFSPDCIMDDAINILQNEKSHQVLAQLLDTLLAIGTKLPENQAIQMRLVDVACKHLTDTSHGVRNKCLQLLGNLGSLEKSVTKDAEGLAARDVQKIIGDYFSDQDPRVRTAAIKAMLQLHERGLKLHQTIYNQACKLLSDDYEQVRSAAVQLIWVVSQLYPESIVPIPSSNEEIRLVDDAFGKICHMVSDGSWVVRVQAAKLLGSMEQVSSHFLEQTLDKKLMSDLRRKRTAHERAKELYSSGEFSSGRKWGDDAPKEEVDTGAVNLIESGACGAFVHGLEDEMYEVRIAAVEALCMLAQSSPSFAEKCLDFLVDMFNDEIEEVRLQSIHTMRKISNNITLREDQLDTVLAVLEDSSRDIREALHELLCCTNVSTKEGIHLALVELLKNLTKYPTDRDSIWKCLKFLGSRHPTLVLPLVPELLSTHPFFDTAEPDMDDPAYIAVLVLIFNAAKTCPTMPALFSDHTFRHYAYLRDSLSHLVPALRLPGRKLVSSAVSPSIIPQEDPSQQFLQQSLERVYSLQHLDPQGAQELLEFTIRDLQRLGELQSELAGVADFSATYLRCQLLLIKALQEKLWNVAAPLYLKQSDLASAAAKQIMEETYKMEFMYSGVENKQVVIIHHMRLQAKALQLIVTARTTRGLDPLFGMCEKFLQEVDFFQRYFIADLPHLQDSFVDKLLDLMPRLMTSKPAEVVKILQTMLRQSAFLHLPLPEQIHKASATIIEPAGESDNPLRFTSGLVVALDVDATLEHVQDPQNTVKVQVLYPDGQAQMIHPKPADFRNPGPGRHRLITQVYLSHTAWTEACQVEVRLLLAYNSSARIPKCPWMEGGEMSPQVETSIEGTIPFSKPVKVYIMPKPARR", "length": 963 }, "evidence": [ { "id": "HGNC:25048", "url": "https://alliancegenome.org/gene/HGNC:25048#orthology", "database": "AGR" }, { "id": "MGI:1917164", "url": "https://alliancegenome.org/gene/MGI:1917164#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-81", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-81#orthology", "database": "AGR" }, { "id": "E7F2X3", "url": "https://omabrowser.org/oma/group/E7F2X3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W3E1-1", "protein_name": "Integrator complex subunit 4", "gene_name": "IntS4", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALAIKKRVGTYVETVDGSPPVKKLRLQTLAADAKGGKSGKVGNVERKLTALNQLDAYVGNLPAGALVLPTGTPVASTGAPSTGVIGNPPAAATGAPPMTAANSRELLELLVKITDEISYEDVEMGELKEVASKIFQLYQLQERDSDTSIRVKLLELLSGLGCECATEQALTMIIDYFIFLLRKEVSQKVLAQGMMCLFRIGERRKHMLPISYKTQVAHLAKEQLRSGSAHTQKNAMLVIGRFATKMEGERHYVWKLAFYIDSQDSSVRAQALHALLTLGERGSQLPAVLYKRAVEAMKDDYECVRKEALQLVFMLGNRHPDYILPSDRQQEELRMIDAAFSKVCEALCDLSLQIRVLAAELLGGMTAVSREFLHQTLDKKLMSNLRRKRTAHERGARLVASGEWSSGKRWADDAPQEHLDAQSISIIASGACGALIHGLEDEFLEVRTAAVASMCKLALSRPDFAVTSLDFLVDMFNDEIEDVRLKAIYSLTAIAKHIVLREDQLEIMLGSLEDYSVDVREGLHLMLGACRVSTQTCLLMVVQKLLDVLAKYPQDRNSTYACMRKIGQKHPHLVMAVAVHLLYVHPFFETPERDVEDPAYLCVLILVFNAAEHLVPIISLLPTATHRHYAYLRDSMPNLVPQLPIEGASSASATHRIDSAMHQAGSSAEYLQMILSHIEEIFTMTDERLELLQTAQSNLQRLGSIDAGMYGTSNFLETFLAAQIQIEQMQRCASTQRSRVPLKESLAALIRNCLKLQHTFSGLNYGDILQVKQLRLRACALHLVLVVRDRSQSALGPCQMLLQTAGDISEFIKANTKDEEEKPPVVETDMPMKESVSRDAQPDSFTRQLLIKLDGISDPKPGRVFREILPLVQQAPPLALPPANDKIRRCVANILEPCPLQSQDNVIKVTAGLIAAVPFVAEIDNLLESQKADMRIKIKYPDQHMHTVVPKQSDFKPIMTEQGEHKTNVRLRTTILLSHSVWTESSLVEIQLCLAVRPGSELELCKPAKVLFAPKPVRRGI", "length": 1022 }, "evidence": [ { "id": "HGNC:25048", "url": "https://alliancegenome.org/gene/HGNC:25048#orthology", "database": "AGR" }, { "id": "MGI:1917164", "url": "https://alliancegenome.org/gene/MGI:1917164#orthology", "database": "AGR" }, { "id": "E7F2X3", "url": "https://omabrowser.org/oma/group/E7F2X3/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7F2X3", "url": "https://www.uniprot.org/uniprotkb/E7F2X3" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7F2X3", "url": "https://www.uniprot.org/uniprotkb/E7F2X3" } ], "pmid": "" }, { "name": "integrator complex", "id": "GO:0032039", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032039", "evidence": [ { "database": "UniProtKB", "id": "E7F2X3", "url": "https://www.uniprot.org/uniprotkb/E7F2X3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "snRNA processing", "id": "GO:0016180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016180", "evidence": [ { "database": "UniProtKB", "id": "E7F2X3", "url": "https://www.uniprot.org/uniprotkb/E7F2X3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 485, "end_pos": 487, "annotation": "n_glycosylation_sequon" }, { "start_pos": 502, "end_pos": 504, "annotation": "n_glycosylation_sequon" }, { "start_pos": 945, "end_pos": 947, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F2X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2X3" }, { "id": "PF24493", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24493" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "INTS4 8 helical bundle", "eco_id": "ECO_0000259", "start_pos": 624, "end_pos": 827, "start_aa": "Lys", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7F2X3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2X3" }, { "id": "PF25458", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25458" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Integrator complex subunit 4/Protein SIEL C-terminal Ig-like", "eco_id": "ECO_0000259", "start_pos": 836, "end_pos": 976, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 485, "end_pos": 487 }, { "start_pos": 502, "end_pos": 504 }, { "start_pos": 945, "end_pos": 947 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B8JKT2-1", "uniprot_ac": "B8JKT2", "uniprot_id": "B8JKT2_DANRE", "mass": { "chemical_mass": 45763.0, "monoisotopic_mass": 45763.0 }, "refseq": { "ac": "NP_001230313", "name": "WD repeat and SOCS box-containing protein 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230313" }, "gene_names": [ { "name": "wsb2", "type": "recommended", "evidence": [ { "id": "B8JKT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKT2" } ] }, { "name": "si:ch73-263f13.4", "type": "synonym", "evidence": [ { "id": "NP_001230313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230313" }, { "id": "B8JKT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKT2" } ] }, { "name": "wsb2", "type": "synonym", "evidence": [ { "id": "NP_001230313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230313" } ] } ], "protein_names": [ { "name": "WD repeat and SOCS box-containing protein 2", "type": "synonym", "evidence": [ { "id": "NP_001230313", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230313" }, { "id": "B8JKT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKT2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: mixed sample support SAMEA4476738, SAMEA4476740 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH433473.1, EH435323.1, EH537750.1 and EH573142.1. On Aug 13, 2011 this sequence version replaced XP_002662016.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001230313", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230313" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JKT2", "url": "https://www.uniprot.org/uniprotkb/B8JKT2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "wsb2", "url": "https://www.uniprot.org/uniprotkb/B8JKT2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-26", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-26", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000058608", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000058608", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100307075", "url": "https://www.ncbi.nlm.nih.gov/gene/100307075", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011047", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011047", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036036", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036036", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051983", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051983", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100307075", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100307075", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WGMAFGP", "url": "https://omabrowser.org/oma/group/WGMAFGP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M6YY44", "url": "https://www.orthodb.org/?gene=A0A8M6YY44", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "B8JKT2", "url": "https://www.orthodb.org/?gene=B8JKT2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15622", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15622", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15622:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15622:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07525", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07525", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001230313", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001230313", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6YY44", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YY44", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6YY44-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6YY44-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JKT2", "url": "https://www.uniprot.org/uniprotkb/B8JKT2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JKT2-1", "url": "https://www.uniprot.org/uniprotkb/B8JKT2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-26", "url": "https://zfin.org/ZDB-GENE-081104-26", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MCAPPQAYNVKEPPELLAELKAAHRPRLYGTPDCETWSARFSPDGSYFAWSMGFGVIKLLPWPLTTRDSAESCCSKEKILNCRFLVWALAFGPCTSTRVDSAHQHRREHELLLAAGLHNGSIQVWLVSTGNLQFTLTGHQAPVRDLVFAPNGSLTLISASRDKTLRIWDLGKKGASPHVLRGPNYWVFRCAVSPDSSVIASVCNLDSKVYLWSLRSYTFMKHLTYDHERTMASCDFSQDGALLAIASYHSNTGWWLDLWDPYTADLLTRVQDCEVCAYRSDNLLTSLSFSPVALLLAFKDYRALQIWDVERDKLVADTDHNRAGGVCCAFHPQGGVIATGCRDGHVKFWKVPHLVPSLRHLCRVALRFSISTYQVEALPLPTKILEYLTYRDIPKQKILYCKEHGR", "length": 406, "header": "tr|B8JKT2-1|B8JKT2_DANRE Isoform 1 of WD repeat and SOCS box-containing protein 2 OS=Danio rerio OX=7955 GN=wsb2 PE=4 SV=1 CANONICAL=B8JKT2-1" }, "isoforms": [ { "isoform_ac": "A0A8M6YY44-1", "url": "https://www.uniprot.org/uniprotkb/B8JKT2/entry#A0A8M6YY44-1", "sequence": { "sequence": "MCAPPQAYNVKEPPELLAELKAAHRPRLYGTPDCETWSARFSPDGSYFAWSMGFGVIKLLPWPLTTRDAESCCSKEKILNCRFLVWALAFGPCTSTRVDSAHQHRREHELLLAAGLHNGSIQVWLVSTGNLQFTLTGHQAPVRDLVFAPNGSLTLISASRDKTLRIWDLGKKGASPHVLRGPNYWVFRCAVSPDSSVIASVCNLDSKVYLWSLRSYTFMKHLTYDHERTMASCDFSQDGALLAIASYHSNTGWWLDLWDPYTADLLTRVQDCEVCAYRSDNLLTSLSFSPVALLLAFKDYRALQIWDVERDKLVADTDHNRAGGVCCAFHPQGGVIATGCRDGHVKFWKVPHLVPSLRHLCRVALRFSISTYQVEALPLPTKILEYLTYRDIPKQKILYCKEHGR", "length": 405, "header": "tr|A0A8M6YY44-1|B8JKT2_DANRE Computationally mapped isoform of WD repeat and SOCS box-containing protein 2 OS=Danio rerio OX=7955 GN=wsb2 PE=4 SV=1 CANONICAL=B8JKT2-1" }, "locus": {} }, { "isoform_ac": "B8JKT2-1", "url": "https://www.uniprot.org/uniprotkb/B8JKT2/entry#B8JKT2-1", "sequence": { "sequence": "MCAPPQAYNVKEPPELLAELKAAHRPRLYGTPDCETWSARFSPDGSYFAWSMGFGVIKLLPWPLTTRDSAESCCSKEKILNCRFLVWALAFGPCTSTRVDSAHQHRREHELLLAAGLHNGSIQVWLVSTGNLQFTLTGHQAPVRDLVFAPNGSLTLISASRDKTLRIWDLGKKGASPHVLRGPNYWVFRCAVSPDSSVIASVCNLDSKVYLWSLRSYTFMKHLTYDHERTMASCDFSQDGALLAIASYHSNTGWWLDLWDPYTADLLTRVQDCEVCAYRSDNLLTSLSFSPVALLLAFKDYRALQIWDVERDKLVADTDHNRAGGVCCAFHPQGGVIATGCRDGHVKFWKVPHLVPSLRHLCRVALRFSISTYQVEALPLPTKILEYLTYRDIPKQKILYCKEHGR", "length": 406, "header": "tr|B8JKT2-1|B8JKT2_DANRE Isoform 1 of WD repeat and SOCS box-containing protein 2 OS=Danio rerio OX=7955 GN=wsb2 PE=4 SV=1 CANONICAL=B8JKT2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JKT2", "url": "https://www.uniprot.org/uniprotkb/B8JKT2" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:100307075", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100307075", "resource": "KEGG Pathway" }, { "id": "R-DRE-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "resource": "Reactome", "description": "Neddylation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AQQ7-1", "protein_name": "WD repeat and SOCS box-containing protein 2", "gene_name": "Wsb2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RRPLEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAWSQGHCVVKLVPWPLEEQFIPKGFEAKSRSSKNDSKGRGSLKEKTLDCGQIVWGLAFSPWPSPPSRKLWLRHHPQVPDVSCLILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPNGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTSVIMWDPYTGERLRSLHHTQLEAPVDDSDVHMSSLRSVCFSPEGLYLATVADDRLLRIWALELKAPVAFAPMTNGLCCTFFPHGGVIATGTRDGHVQFWTAPRVLSSLKHLCRKALRRFLTTYQVLALPIPKKMKDFLTYRTL", "length": 404 }, "evidence": [ { "id": "MGI:2144041", "url": "https://alliancegenome.org/gene/MGI:2144041#orthology", "database": "AGR" }, { "id": "HGNC:19222", "url": "https://alliancegenome.org/gene/HGNC:19222#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O54929-1", "protein_name": "WD repeat and SOCS box-containing protein 2", "gene_name": "Wsb2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEAGEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAWSQGHCVVKLVPWPLEEQFIPKGFEAKSRSSKNDPKGRGSLKEKTLDCGQIVWGLAFSPWPSPPSRKLWARHHPQAPDVSCLILATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTSVIMWDPYTGERLRSLHHTQLEPTMDDSDVHMSSLRSVCFSPEGLYLATVADDRLLRIWALELKAPVAFAPMTNGLCCTFFPHGGIIATGTRDGHVQFWTAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRTF", "length": 404 }, "evidence": [ { "id": "MGI:2144041", "url": "https://alliancegenome.org/gene/MGI:2144041#orthology", "database": "AGR" }, { "id": "HGNC:19222", "url": "https://alliancegenome.org/gene/HGNC:19222#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-26", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-26#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NYS7-1", "protein_name": "WD repeat and SOCS box-containing protein 2", "gene_name": "WSB2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAGEEPLLLAELKPGRPHQFDWKSSCETWSVAFSPDGSWFAWSQGHCIVKLIPWPLEEQFIPKGFEAKSRSSKNETKGRGSPKEKTLDCGQIVWGLAFSPWPSPPSRKLWARHHPQVPDVSCLVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPDSALLVTASYDTNVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSPEGLYLATVADDRLLRIWALELKTPIAFAPMTNGLCCTFFPHGGVIATGTRDGHVQFWTAPRVLSSLKHLCRKALRSFLTTYQVLALPIPKKMKEFLTYRTF", "length": 404 }, "evidence": [ { "id": "MGI:2144041", "url": "https://alliancegenome.org/gene/MGI:2144041#orthology", "database": "AGR" }, { "id": "HGNC:19222", "url": "https://alliancegenome.org/gene/HGNC:19222#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-26", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-26#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "B8JKT2", "url": "https://www.uniprot.org/uniprotkb/B8JKT2" } ], "pmid": "" }, { "name": "protein ubiquitination", "id": "GO:0016567", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016567", "evidence": [ { "database": "UniProtKB", "id": "B8JKT2", "url": "https://www.uniprot.org/uniprotkb/B8JKT2" } ], "pmid": "" }, { "name": "protein polyubiquitination", "id": "GO:0000209", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000209", "evidence": [ { "database": "UniProtKB", "id": "B8JKT2", "url": "https://www.uniprot.org/uniprotkb/B8JKT2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 119, "end_pos": 121, "annotation": "n_glycosylation_sequon" }, { "start_pos": 151, "end_pos": 153, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8JKT2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKT2" }, { "id": "PS50225", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50225" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SOCS box", "eco_id": "ECO_0000259", "start_pos": 355, "end_pos": 394, "start_aa": "Val", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 119, "end_pos": 121 }, { "start_pos": 151, "end_pos": 153 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7FF73-1", "uniprot_ac": "E7FF73", "uniprot_id": "E7FF73_DANRE", "mass": { "chemical_mass": 53962.0, "monoisotopic_mass": 53962.0 }, "refseq": { "ac": "XP_021324911", "name": "amyloid-beta A4 precursor protein-binding family B member 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324911" }, "gene_names": [ { "name": "apbb3", "type": "recommended", "evidence": [ { "id": "E7FF73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FF73" } ] }, { "name": "apbb3", "type": "synonym", "evidence": [ { "id": "XP_021324911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324911" } ] } ], "protein_names": [ { "name": "Amyloid-beta A4 precursor protein-binding family B member 3", "type": "recommended", "evidence": [ { "id": "E7FF73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FF73/entry#names_and_taxonomy" } ] }, { "name": "Protein Fe65-like 2", "type": "synonym", "evidence": [ { "id": "E7FF73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FF73/entry#names_and_taxonomy" } ] }, { "name": "amyloid-beta A4 precursor protein-binding family B member 3", "type": "synonym", "evidence": [ { "id": "XP_021324911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324911" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021324911", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021324911" } ] }, { "annotation": "May modulate the internalization of amyloid-beta precursor protein.", "evidence": [ { "database": "UniProtKB", "id": "E7FF73", "url": "https://www.uniprot.org/uniprotkb/E7FF73#function" }, { "database": "UniProtKB", "id": "ARBA00053046", "url": "https://www.uniprot.org/uniprotkb/ARBA00053046#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FF73", "url": "https://www.uniprot.org/uniprotkb/E7FF73" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "apbb3", "url": "https://www.uniprot.org/uniprotkb/E7FF73", "locus": {} } ], 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"https://www.uniprot.org/uniprotkb/E7FF73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-140106-53", "url": "https://zfin.org/ZDB-GENE-140106-53", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLGKDYMLAIIIVNYDDNIWNDQSLELDSDLPPGWRTIRDSTGTYYWHVPTGTTQWQHPSYSAEEEQNAINGVTASQIKLAADGRRESRGRLTENPLPSLSERPSWQEEYFCANMDPDSKCFAVRSLGWVEIPEEELTPGKSSLAVNNCIQQLSHSKAEGRDAEGAWGEGQDMMMVLKKDTLSLMDPVDQSLIHCQPIINIRVWGVGCNNGRDFAFVASDKDTCMLKCHVFRCNAPAKTIASALHEMCSKIMTEKAALQPSMARSLTMESISPEDLPRQVDFLEAVRQRVQKFEVEYIGNLPVSRAMGMEVLNRAIESIMHSRDRDEWEPIVIHVSDTVLSLWRGEDGDDPFWESQVRYLTFLGVGHDTHTFAVIVDAGTQRFECHVFWCEPDAGIISEAVQAACMVQYQKCLVAQTPPVRPKIWRAGSKVKRANSMDGSSFPPRYQGHTASKMTSPSVKKGMLAFFETFRNKHSAVSTP", "length": 480, "header": "tr|E7FF73-1|E7FF73_DANRE Isoform 1 of Amyloid-beta A4 precursor protein-binding family B member 3 OS=Danio rerio OX=7955 GN=apbb3 PE=4 SV=1 CANONICAL=E7FF73-1" }, "isoforms": [ { "isoform_ac": "E7FF73-1", "url": "https://www.uniprot.org/uniprotkb/E7FF73/entry#E7FF73-1", "sequence": { "sequence": "MLGKDYMLAIIIVNYDDNIWNDQSLELDSDLPPGWRTIRDSTGTYYWHVPTGTTQWQHPSYSAEEEQNAINGVTASQIKLAADGRRESRGRLTENPLPSLSERPSWQEEYFCANMDPDSKCFAVRSLGWVEIPEEELTPGKSSLAVNNCIQQLSHSKAEGRDAEGAWGEGQDMMMVLKKDTLSLMDPVDQSLIHCQPIINIRVWGVGCNNGRDFAFVASDKDTCMLKCHVFRCNAPAKTIASALHEMCSKIMTEKAALQPSMARSLTMESISPEDLPRQVDFLEAVRQRVQKFEVEYIGNLPVSRAMGMEVLNRAIESIMHSRDRDEWEPIVIHVSDTVLSLWRGEDGDDPFWESQVRYLTFLGVGHDTHTFAVIVDAGTQRFECHVFWCEPDAGIISEAVQAACMVQYQKCLVAQTPPVRPKIWRAGSKVKRANSMDGSSFPPRYQGHTASKMTSPSVKKGMLAFFETFRNKHSAVSTP", "length": 480, "header": "tr|E7FF73-1|E7FF73_DANRE Isoform 1 of Amyloid-beta A4 precursor protein-binding family B member 3 OS=Danio rerio OX=7955 GN=apbb3 PE=4 SV=1 CANONICAL=E7FF73-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101883158", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101883158", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O35827-1", "protein_name": "Amyloid-beta A4 precursor protein-binding family B member 3", "gene_name": "Apbb3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGKDYMLAIILVNCDDDLWGDQNLEGETGLPPGWRKIRDAAGTYYWHVPSGSTQWQRPTWELAEDPGTGKEGIWELRPPKGRSFSSLDSSLNRSNSLTWYNEDSYVRSLEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQARNRSQPHDGAWGEGQNMLMVLKKDAMSLLNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVAGDKDSCMLKCHVFRCDVPAKAIASRLQGLCAQILSERVGLSGEAACCSPDPISPEDFPRQVELLDAVSQAAQKYEALYMGILPVTKAMGMDVLNEAIGTLTGRGDRKTWVPAMLSVSDSLMTAHPIQAEAGAEEEPLWQCPVRLVTFIGVGHDPHTFGLIADLGCQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVASAARGKAWGAQARARLRLKRTSSMDSPGGPLPPPLLKGGVGGAGAAPRKRGVFSFLDAFRLKPLFSICPKLILEGWGKRLYTLPVPRVL", "length": 504 }, "evidence": [ { "id": "RGD:620853", "url": "https://alliancegenome.org/gene/RGD:620853#orthology", "database": "AGR" }, { "id": "MGI:108404", "url": "https://alliancegenome.org/gene/MGI:108404#orthology", "database": "AGR" }, { "id": "HGNC:20708", "url": "https://alliancegenome.org/gene/HGNC:20708#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-53", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-53#orthology", "database": "AGR" }, { "id": "E7FF73", "url": "https://omabrowser.org/oma/group/E7FF73/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O95704-1", "protein_name": "Amyloid-beta A4 precursor protein-binding family B member 3", "gene_name": "APBB3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGKDYMLAIILVNCDDDLWGDHSLEVEAGLPPGWRKIHDAAGTYYWHVPSGSTQWQRPTWELGDAEDPGTGTEGIWGLRPPKGRSFSSLESSLDRSNSLSWYGGESYIQSMEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRSRSQPPDGAWGEGQNMLMILKKDAMSLVNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVASDKDSCMLKCHVFCCDVPAKAIASALHGLCAQILSERVEVSGDASCCSPDPISPEDLPRQVELLDAVSQAAQKYEALYMGTLPVTKAMGMDVLNEAIGTLTARGDRNAWVPTMLSVSDSLMTAHPIQAEASTEEEPLWQCPVRLVTFIGVGRDPHTFGLIADLGRQSFQCAAFWCQPHAGGLSEAVQAACMVQYQKCLVASAARGKAWGAQARARLRLKRTSSMDSPGGPLPLPLLKGGVGGAGATPRKRGVFSFLDAFRLKPSLLHMP", "length": 486 }, "evidence": [ { "id": "RGD:620853", "url": "https://alliancegenome.org/gene/RGD:620853#orthology", "database": "AGR" }, { "id": "MGI:108404", "url": "https://alliancegenome.org/gene/MGI:108404#orthology", "database": "AGR" }, { "id": "HGNC:20708", "url": "https://alliancegenome.org/gene/HGNC:20708#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-53", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-53#orthology", "database": "AGR" }, { "id": "E7FF73", "url": "https://omabrowser.org/oma/group/E7FF73/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R1C9-1", "protein_name": "Amyloid-beta A4 precursor protein-binding family B member 3", "gene_name": "Apbb3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGKDYMLAIILVNCDDDLWGDQNLEGETGLPPGWRKIRDAAGTYYWHVPSGSTQWQRPTWELPGAEDPGRGTEGIWELRPPKGRSFSSLDSSLNRSNSLTWYSEDSYVRSLEPGAKCFAVRSLGWVEVPEEDLAPGKSSIAVNNCIQQLAQTRNRSQPHDGTWGEGQNMLMILKKDAMSLLNPLDHSLIHCQPLVHIRVWGVGSSKGRDRDFAFVAGDKDSCMLKCHVFHCDVPAKAIASALQGLCAQILSERVGVSGEAACCSPDPISPEDLPRQVELLDAVSQAAQKYEALYMGILPVTKAMGMDVLNEAIGTLTARGDRKTWVPAMLSVSDSLMTAHAIQAEAGAEEEPLWQCPVRLVTFIGVGRDPHTFGLIADLGCQSFQCAAFWCEPHAGGLSEAVQAACMVQYQKCLVASAARGKAWGAQARARLRLKRTSSMDSPGGPLPPPLLKGGAGGAGAAPRKRGVFSFLDAFRLKPSLLHMS", "length": 486 }, "evidence": [ { "id": "RGD:620853", "url": "https://alliancegenome.org/gene/RGD:620853#orthology", "database": "AGR" }, { "id": "MGI:108404", "url": "https://alliancegenome.org/gene/MGI:108404#orthology", "database": "AGR" }, { "id": "HGNC:20708", "url": "https://alliancegenome.org/gene/HGNC:20708#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140106-53", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140106-53#orthology", "database": "AGR" }, { "id": "E7FF73", "url": "https://omabrowser.org/oma/group/E7FF73/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7FF73", "url": "https://www.uniprot.org/uniprotkb/E7FF73" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7FF73", "url": "https://www.uniprot.org/uniprotkb/E7FF73" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "amyloid-beta binding", "id": "GO:0001540", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001540", "evidence": [ { "database": "UniProtKB", "id": "E7FF73", "url": "https://www.uniprot.org/uniprotkb/E7FF73" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FF73", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FF73" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 255, "start_aa": "Phe", "end_aa": "Lys", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7FF73", "database": "UniProtKB", "url": 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"https://www.ebi.ac.uk/interpro/entry/IPR020472", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040102", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040102", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:571294", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571294", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VCLWNAQ", "url": "https://omabrowser.org/oma/group/VCLWNAQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "F1Q4U0", "url": "https://www.orthodb.org/?gene=F1Q4U0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22805", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22805", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22805:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22805:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25178", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25178", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001025432", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001025432", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PU15", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PU15", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PU15-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PU15-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q4U0", "url": "https://www.uniprot.org/uniprotkb/F1Q4U0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q4U0-1", "url": "https://www.uniprot.org/uniprotkb/F1Q4U0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050706-152", "url": "https://zfin.org/ZDB-GENE-050706-152", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLRWILGGREAQGAVEKSAALFIGEEQPKNCFTEMQVLKGHFDIVRFLVQIDDLRFASAGDDGLVLIWNVETGDCLLELRGHTQQITAMTSYTFIRGGNTHTALITASSDRTLSLWDPDSGNRVQNISDLQSSVKCLLVLNLLDMWLSGGNELCVWNQDFELQCKTVHHSDTGISAMVELPKNFIAAAMDKEIVIFKLNVSGSDVAVMAIRHLADHQDTIHSLISINDGLFASGSHIGELIIWDSVDWTIQGYELILWEESKGDGHSEVKVTQQKQIERSIQHMSSDGELLVAAVGSGLYVYNVLTKTVVAYRKMAHDSNVLHTMIQTDGLMSCSEDGSVRMWELQDLPLPAEPASSGFFGMFGTFGRSSKHAGPPAKKLPEVPDLRSLELIGDLIGHSGAVQMFVSFEQKALVTCSTDHLLIVWKDGELQSQLRSLAVFQKLEENQQL", "length": 449, "header": "tr|F1Q4U0-1|F1Q4U0_DANRE Isoform 1 of WD repeat-containing protein 41 OS=Danio rerio OX=7955 GN=wdr41 PE=4 SV=1 CANONICAL=F1Q4U0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PU15-1", "url": "https://www.uniprot.org/uniprotkb/F1Q4U0/entry#A0A8M9PU15-1", "sequence": { "sequence": "MTSYTFIRGGNTHTALITASSDRTLSLWDPDSGNRVQNISDLQSSVKCLLVLNLLDMWLSGGNELCVWNQDFELQCKTVHHSDTGISAMVELPKNFIAAAMDKEIVIFKLNVSGSDVAVMAIRHLADHQDTIHSLISINDGLFASGSHIGELIIWDSVDWTIQGYELILWEESKGDGHSEVKVTQQKQIERSIQHMSSDGELLVAAVGSGLYVYNVLTKTVVAYRKMAHDSNVLHTMIQTDGLMSCSEDGSVRMWELQDLPLPAEPASSGFFGMFGTFGRSSKHAGPPAKKLPEVPDLRSLELIGDLIGHSGAVQMFVSFEQKALVTCSTDHLLIVWKDGELQSQLRSLAVFQKLEENQQL", "length": 361, "header": "tr|A0A8M9PU15-1|F1Q4U0_DANRE Computationally mapped isoform of WD repeat-containing protein 41 OS=Danio rerio OX=7955 GN=wdr41 PE=4 SV=1 CANONICAL=F1Q4U0-1" }, "locus": {} }, { "isoform_ac": "F1Q4U0-1", "url": "https://www.uniprot.org/uniprotkb/F1Q4U0/entry#F1Q4U0-1", "sequence": { "sequence": "MLRWILGGREAQGAVEKSAALFIGEEQPKNCFTEMQVLKGHFDIVRFLVQIDDLRFASAGDDGLVLIWNVETGDCLLELRGHTQQITAMTSYTFIRGGNTHTALITASSDRTLSLWDPDSGNRVQNISDLQSSVKCLLVLNLLDMWLSGGNELCVWNQDFELQCKTVHHSDTGISAMVELPKNFIAAAMDKEIVIFKLNVSGSDVAVMAIRHLADHQDTIHSLISINDGLFASGSHIGELIIWDSVDWTIQGYELILWEESKGDGHSEVKVTQQKQIERSIQHMSSDGELLVAAVGSGLYVYNVLTKTVVAYRKMAHDSNVLHTMIQTDGLMSCSEDGSVRMWELQDLPLPAEPASSGFFGMFGTFGRSSKHAGPPAKKLPEVPDLRSLELIGDLIGHSGAVQMFVSFEQKALVTCSTDHLLIVWKDGELQSQLRSLAVFQKLEENQQL", "length": 449, "header": "tr|F1Q4U0-1|F1Q4U0_DANRE Isoform 1 of WD repeat-containing protein 41 OS=Danio rerio OX=7955 GN=wdr41 PE=4 SV=1 CANONICAL=F1Q4U0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "F1Q4U0", "url": "https://www.uniprot.org/uniprotkb/F1Q4U0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "F1Q4U0", "url": "https://www.uniprot.org/uniprotkb/F1Q4U0" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:571294", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571294", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BWY4-1", "protein_name": "WD repeat-containing protein 41", "gene_name": "WDR41", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLRWLIGGGREPQGLAEKSSVQTIGEEQVQNPYTELLVLKGHQDIVRFLVQIDDYRFASAGDDGIIFLWNAQTGEKLFELHGHTHKITAIAPFFSSDASEENSHLILTASADRAVIVWDCTTGRQVQKVSCFHSTVKCLTVLQRLDVWLSGGSDLCVWNRKLDLLCKTSHLTDAGISALVELPKNCVAAAVGKELIIFRLIASSDKSEGWNILEVKRLVDHQDNILSLVSVNDLTFATGSHVGELIVWDALDWTKQASECNFWDSSVQPDTRTEIKLSQSPNETSVQHLASDEENVYAAVGKGIYVYNLQMKRVIACQRTAHDSSVLHIEMLPNRQLISCSEDGSVRIWEIREKQQLPTEPVPTGFFNMWGFGRANKQANQAKKVQENTPMHFLELVGDLIGHSSAVQMFLYFSELGLVTCSADHLVILWKDGERESRLRSLTLFQKLAQNGDLQLKF", "length": 458 }, "evidence": [ { "id": "F1Q4U0", "url": "https://omabrowser.org/oma/group/F1Q4U0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q3UDP0-1", "protein_name": "WD repeat-containing protein 41", "gene_name": "Wdr41", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRWLIGGGREPQGLAEKAALQTIGEDQGQNPYTELLVLEAHRDIVRFLVRLDDFRFASAGDDGIIVVWNAQTGEKLLELRGHTQKITAVIAFPPLDSCEASSQLLLTASADRTVGVWDCDTGRQIQRVTCFQSTVKCLTVLQRLDIWLSGGSDLGVWNRKLDLLCKTSHLSDTGISALVEIPGNCVAAAVGRELIIFRLVTPTEELPEWDIIEVKRLLDHQDNILSLANINDTGFVTGSHVGELLIWDALDWTVQACERTFWSPTAQLDAQQEIKLFQKQNDISINHFTCDEENIFAAVGRGLYVYNLQLKRVIACQKTAHDSNILHIDKLPNRQLISCSEDGAVRMWEVREKQQLAAEPVPTGFFNMWGFGRVNKQASQPVKKQEENVTTCSLELIGDLIGHSSSVEMFLYFEDHGLVTCSADHLIILWKNGERESGVRSLKLFQKLEENGDLYPESP", "length": 460 }, "evidence": [ { "id": "MGI:2445123", "url": "https://alliancegenome.org/gene/MGI:2445123#orthology", "database": "AGR" }, { "id": "HGNC:25601", "url": "https://alliancegenome.org/gene/HGNC:25601#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050706-152", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050706-152#orthology", "database": "AGR" }, { "id": "F1Q4U0", "url": "https://omabrowser.org/oma/group/F1Q4U0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9HAD4-1", "protein_name": "WD repeat-containing protein 41", "gene_name": "WDR41", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRWLIGGGREPQGLAEKSPLQTIGEEQTQNPYTELLVLKAHHDIVRFLVQLDDYRFASAGDDGIVVVWNAQTGEKLLELNGHTQKITAIITFPSLESCEEKNQLILTASADRTVIVWDGDTTRQVQRISCFQSTVKCLTVLQRLDVWLSGGNDLCVWNRKLDLLCKTSHLSDTGISALVEIPKNCVVAAVGKELIIFRLVAPTEGSLEWDILEVKRLLDHQDNILSLINVNDLSFVTGSHVGELIIWDALDWTMQAYERNFWDPSPQLDTQQEIKLCQKSNDISIHHFTCDEENVFAAVGRGLYVYSLQMKRVIACQKTAHDSNVLHVARLPNRQLISCSEDGSVRIWELREKQQLAAEPVPTGFFNMWGFGRVSKQASQPVKKQQENATSCSLELIGDLIGHSSSVEMFLYFEDHGLVTCSADHLIILWKNGERESGLRSLRLFQKLEENGDLYLAV", "length": 459 }, "evidence": [ { "id": "MGI:2445123", "url": "https://alliancegenome.org/gene/MGI:2445123#orthology", "database": "AGR" }, { "id": "HGNC:25601", "url": "https://alliancegenome.org/gene/HGNC:25601#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050706-152", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050706-152#orthology", "database": "AGR" }, { "id": "F1Q4U0", "url": "https://omabrowser.org/oma/group/F1Q4U0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of autophagy", "id": "GO:0010506", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010506", "evidence": [ { "database": "UniProtKB", "id": "F1Q4U0", "url": "https://www.uniprot.org/uniprotkb/F1Q4U0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 126, "end_pos": 128, "annotation": "n_glycosylation_sequon" }, { "start_pos": 199, "end_pos": 201, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 126, "end_pos": 128 }, { "start_pos": 199, "end_pos": 201 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JIG8-1", "uniprot_ac": "B8JIG8", "uniprot_id": "B8JIG8_DANRE", "mass": { "chemical_mass": 83870.0, "monoisotopic_mass": 83870.0 }, "refseq": { "ac": "NP_001164413", "name": "kelch-like protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164413" }, "gene_names": [ { "name": "klhl5", "type": "recommended", "evidence": [ { "id": "B8JIG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JIG8" } ] }, { "name": "klhl5", "type": "synonym", "evidence": [ { "id": "NP_001164413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164413" } ] } ], "protein_names": [ { "name": "Kelch-like protein 5", "type": "synonym", "evidence": [ { "id": "B8JIG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JIG8/entry#names_and_taxonomy" } ] }, { "name": "kelch-like 5", "type": "synonym", "evidence": [ { "id": "NP_001164413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164413" } ] }, { "name": "kelch-like protein 5", "type": "synonym", "evidence": [ { "id": "NP_001164413", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164413" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01014095.1, SRR32588729.30136507.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000001.1. On Apr 26, 2010 this sequence version replaced XP_689186.4.", "evidence": [ { "database": "RefSeq", "id": "NP_001164413", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164413" } ] } ], "disease": [ { "disease_id": "DOID:9975", "recommended_name": { "id": "DOID:9975", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9975", "name": "cocaine dependence", "description": "A drug dependence that is a psychological dependency on the regular use of cocaine." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "9975", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9975" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JIG8", "url": "https://www.uniprot.org/uniprotkb/B8JIG8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "klhl5", "url": "https://www.uniprot.org/uniprotkb/B8JIG8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080424-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080424-7", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000062122", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000062122", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18234", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18234", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18511", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18511", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "560697", "url": "https://www.ncbi.nlm.nih.gov/gene/560697", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:560697", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560697", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AWTVMPP", "url": "https://omabrowser.org/oma/group/AWTVMPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JIG8", "url": "https://www.orthodb.org/?gene=B8JIG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF26", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF26", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001164413", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164413", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PUZ1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PUZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PUZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PUZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JIG8", "url": "https://www.uniprot.org/uniprotkb/B8JIG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JIG8-1", "url": "https://www.uniprot.org/uniprotkb/B8JIG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080424-7", "url": "https://zfin.org/ZDB-GENE-080424-7", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSNPRKDFDVKQILRIRWRWFGHPTSPPSPGNQPSGDLFSNSGGSGNSSRGNGGASSGGDQPSLGGCSSSNAAAGASSSNGNLSSNINNSRKFGDSGPNSGHSAAAVVISGTACPRSMSQQECRSSPPAPWVFPVHSRSSESLEPLQQQPQQPQQQPQKQQSTRAPDASGPGDEENNNNVESDSSSCRTSNSSVTLSSCASMEPCVSDEHFQAHSHAEHTFRRMEAYLRTRKLCDVVLLAGDRRIPAHRLVLSSVSDYFAAMFTSDVREAKQEEIKMEGVDPDALWVLVQYAYTGRLELREDTIESLLSGSCLLQLSAVVQACCSYLMKQLHPSNCLGIRSFADAQGCLDLHKVAHNYTMEHFMEVMRHQEFLLLPSCEVEKLLASDDMNVPEEETVVTALLSWVRHDVTTRQSQLSALLAHIRLPLLKPQFLADMEANPLLRDSVECQRLVMEAMKYHLLPERRPLLQSPRTRPRKATVGALFAVGGMDATKGATSIEQYCLRRDTWRQVAVMSGRRLQFGVAVLDDRLYVVGGRDGLKTLNTVECYNPRSKSWSVMPPMSTHRHGLGVAVLEGPMYAVGGHDGWSYLSTVERWDPQARQWSFVASMATPRSTVGVAVLNSKLYAVGGRDGSSCLKSVECFDPHTNKWSSCAPMSKRRGGVGVATWNGFLYAIGGHDAPASSLASRLSDCVERYDPKTDMWTAVAPMSLSRDAVGVCLLGDRLYAVGGYDGQVYLNTVEAYDPQTNEWTQVAPLCLGRAGACVVAVKL", "length": 769, "header": "tr|B8JIG8-1|B8JIG8_DANRE Isoform 1 of Kelch-like protein 5 OS=Danio rerio OX=7955 GN=klhl5 PE=4 SV=1 CANONICAL=B8JIG8-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PUZ1-1", "url": "https://www.uniprot.org/uniprotkb/B8JIG8/entry#A0A8M9PUZ1-1", "sequence": { "sequence": "MEPCVSDEHFQAHSHAEHTFRRMEAYLRTRKLCDVVLLAGDRRIPAHRLVLSSVSDYFAAMFTSDVREAKQEEIKMEGVDPDALWVLVQYAYTGRLELREDTIESLLSGSCLLQLSAVVQACCSYLMKQLHPSNCLGIRSFADAQGCLDLHKVAHNYTMEHFMEVMRHQEFLLLPSCEVEKLLASDDMNVPEEETVVTALLSWVRHDVTTRQSQLSALLAHIRLPLLKPQFLADMEANPLLRDSVECQRLVMEAMKYHLLPERRPLLQSPRTRPRKATVGALFAVGGMDATKGATSIEQYCLRRDTWRQVAVMSGRRLQFGVAVLDDRLYVVGGRDGLKTLNTVECYNPRSKSWSVMPPMSTHRHGLGVAVLEGPMYAVGGHDGWSYLSTVERWDPQARQWSFVASMATPRSTVGVAVLNSKLYAVGGRDGSSCLKSVECFDPHTNKWSSCAPMSKRRGGVGVATWNGFLYAIGGHDAPASSLASRLSDCVERYDPKTDMWTAVAPMSLSRDAVGVCLLGDRLYAVGGYDGQVYLNTVEAYDPQTNEWTQVAPLCLGRAGACVVAVKL", "length": 568, "header": "tr|A0A8M9PUZ1-1|B8JIG8_DANRE Computationally mapped isoform of Kelch-like protein 5 OS=Danio rerio OX=7955 GN=klhl5 PE=4 SV=1 CANONICAL=B8JIG8-1" }, "locus": {} }, { "isoform_ac": "B8JIG8-1", "url": "https://www.uniprot.org/uniprotkb/B8JIG8/entry#B8JIG8-1", "sequence": { "sequence": "MSNPRKDFDVKQILRIRWRWFGHPTSPPSPGNQPSGDLFSNSGGSGNSSRGNGGASSGGDQPSLGGCSSSNAAAGASSSNGNLSSNINNSRKFGDSGPNSGHSAAAVVISGTACPRSMSQQECRSSPPAPWVFPVHSRSSESLEPLQQQPQQPQQQPQKQQSTRAPDASGPGDEENNNNVESDSSSCRTSNSSVTLSSCASMEPCVSDEHFQAHSHAEHTFRRMEAYLRTRKLCDVVLLAGDRRIPAHRLVLSSVSDYFAAMFTSDVREAKQEEIKMEGVDPDALWVLVQYAYTGRLELREDTIESLLSGSCLLQLSAVVQACCSYLMKQLHPSNCLGIRSFADAQGCLDLHKVAHNYTMEHFMEVMRHQEFLLLPSCEVEKLLASDDMNVPEEETVVTALLSWVRHDVTTRQSQLSALLAHIRLPLLKPQFLADMEANPLLRDSVECQRLVMEAMKYHLLPERRPLLQSPRTRPRKATVGALFAVGGMDATKGATSIEQYCLRRDTWRQVAVMSGRRLQFGVAVLDDRLYVVGGRDGLKTLNTVECYNPRSKSWSVMPPMSTHRHGLGVAVLEGPMYAVGGHDGWSYLSTVERWDPQARQWSFVASMATPRSTVGVAVLNSKLYAVGGRDGSSCLKSVECFDPHTNKWSSCAPMSKRRGGVGVATWNGFLYAIGGHDAPASSLASRLSDCVERYDPKTDMWTAVAPMSLSRDAVGVCLLGDRLYAVGGYDGQVYLNTVEAYDPQTNEWTQVAPLCLGRAGACVVAVKL", "length": 769, "header": "tr|B8JIG8-1|B8JIG8_DANRE Isoform 1 of Kelch-like protein 5 OS=Danio rerio OX=7955 GN=klhl5 PE=4 SV=1 CANONICAL=B8JIG8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Saltatory evolution of the ectodermal neural cortex gene family at the vertebrate origin.", "journal": "Genome Biol. Evol.", "date": "2013", "authors": "Feiner Nathalie, Murakami Yasunori, Breithut Lisa, Mazan Sylvie, Meyer Axel, Kuraku Shigehiro", "evidence": [ { "database": "UniProtKB", "id": "B8JIG8", "url": "https://www.uniprot.org/uniprotkb/B8JIG8" } ], "reference": [ { "type": "PubMed", "id": "23843192", "url": "https://glygen.org/publication/PubMed/23843192" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8JIG8", "url": "https://www.uniprot.org/uniprotkb/B8JIG8" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:560697", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560697", "resource": "KEGG Pathway" }, { "id": "R-DRE-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-DRE-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "B1AZR0-1", "protein_name": "Kelch-like 4", "gene_name": "Klhl4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSVSGKKEFDVKQILRLRWRWFSHPSQGSPNTGSCLQQEGYEHRGTPVQGRLKNHSRDRNGLKKSNSPVHHDILTPVPGPAPTHQRVLQNWHQQNVIVHLQANEDTPKAVPEGNLLKEACEKRSRDLEMMGDDNIEDMRAGPCVEEPEQMTTSSNDHYRSRSHADYTLCKMESYLKERKLCDVLLIAGPLKIPAHRLVLSAVSDYFAAMFTNDVLEARQEEVKIEGVDPNALNSLVQYAYTGVLQLREDTIENLLSAACLLQLTQVIDVCCNFLIKQLHPSNCLGIRSFGDAQGCMELQNVAHKYAMEHFIDVIKNQEFLLLPANEISKLLCSDDINVPDEETIFHALMQWVGHDAQARQRDLAKLLSYIRLPLLSPQLLADLENSSFFSGNLECQKLLMEAMKYHLLPERRSMLQSPRTKPRKSTVGALYAVGGMDAAKGTTTIEKYDLRTNSWIHIGTMSGRRLQFGVAVVDNKLYVVGGRDGLKTLNTVECFNPVTKTWVVMPPMSTHRHGLGVATLEGPMYAVGGHDGWSYLNTVERWDPDGRQWNYVASMSTPRSTVGVVALNNRLYAIGGRDGSSCLKSMEFFDPHTNKWSLCAPMSKRRGGVGVATHNGYLYVVGGHDAPAPNHCSRLSDCVERYDPKGDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYLNTVESYDAQKDEWKEEVPVNIGRAGACVVVVKLQ", "length": 717 }, "evidence": [ { "id": "B8JIG8", "url": "https://omabrowser.org/oma/group/B8JIG8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZHI3-1", "protein_name": "Kelch-like family member 4", "gene_name": "Klhl4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSVSGKKEFDVKQILRLRWRWFSHPSQGSPNTGSCLQQEGYEHRGTPVQGRLKNHSRDRNGLKKSNSPVHHDILTPVPGPAPTHQRVLQNWHQQNVIVHLQANEDTPKAVPEGNLLKEACEKRARDLEMMGDDNIEDSRARQYAEEPEQMNVISEDHYRSRNHADYTLCKMESYLKEKKLCDVLLIAGPLKIPAHRLVLSAVSDYFAAMFTNDVLEARQEEVKMEGVDPNALNSLVQYAYTGVLQLREDTIENLLSAACLLQLTQVIDVCCNFLIKQLHPSNCLGIRSFGDAQGCMELQNVAHKYTMEHFIDVVKNQEFLLLPANEISKLLCSDDINVPDEETIFHALMQWVGHDAQARQQDLAKLLSYIRLPLLSPQLLADLENSSMFSGDLECQKLLMEAMKYHLLPERRSMLQSPRTKPRKSTVGALYAVGGMDAAKGTTTIEKYDLRTNSWIHIGTMSGRRLQFGVAVVDNKLYVVGGRDGLKTLNTVECFNPVTKTWVVMPPMSTHRHGLGVATLEGPMYAVGGHDGWSYLNTVERWDPDGRQWNYVASMSTPRSTVGVVALNNKLYAIGGRDGSSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATHNGYLYVVGGHDAPAPNHCSRLSDCVERYDPKSDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYLNTVESYDAQKDEWKEEVPVNIGRAGACVVVVKLH", "length": 717 }, "evidence": [ { "id": "B8JIG8", "url": "https://omabrowser.org/oma/group/B8JIG8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S1P2-1", "protein_name": "Kelch like family member 4", "gene_name": "KLHL4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSVSGKKEFDVKQILRLRWRWFSHPSQGSPNTGNCLQQEGYEHRGTPVQGRLKSHPRDRNGLKKSNSPVHHSILAPVPGPAPAHQRALQNWHPQNLIEHLQANEDTPKAVPEENLFKKSCEKHSQDLEMMADDNTEDSTARLDTQHPKEMNVSRSEEQFHAVNHAEQTLHKMENYLKDKQLCDVLLIAGHLRIPAHRLVLSAVSDYFAAMFTNDVLEAKQEEVKMEGIDPNALNSLVQYAYTGVLQLKEDTIENLLAAACLLQLTQVVEVCSNFLIKQLHPSNCLGIRSFGDAQGCTELLSVAHKYTMEHFIEVIKNQEFLLLPANEISKLLCSDDINVPDEETIFHALMQWVGHDAQARQQDLAMLLSYIRLPLLPPQLLADLENSSMFTGDLECQKLLMEAMKYHLLPERRPMMQSPRTKPRKSTVGALYAVGGMDAMKGTTTIEKYDLRTNSWLHIGTMSGRRLQFGVAVIDNKLYVVGGRDGLKTLNTVECFNPVGKIWTVMPPMSTHRHGLGVATLEGPMYAVGGHDGWSYLNTVERWDPEGRQWNYVASMSTPRSTVGVVALNNKLYAIGGRDGSSCLRSMEYFDPHTNKWSLCAPMSKRRGGVGVATYNGFLYVVGGHDAPASNHCSRLSDCVERYDPKNDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYLNTVESYDAQKDEWKEEVPVNIGRAGACVVVVKLP", "length": 718 }, "evidence": [ { "id": "B8JIG8", "url": "https://omabrowser.org/oma/group/B8JIG8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q96PQ7-1", "protein_name": "Kelch-like protein 5", "gene_name": "KLHL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNVIYFPLHIFVVYSRAYTSLVLVGCTNLCAVLFARCLDDHLVSLRMSGSRKEFDVKQILKIRWRWFGHQASSPNSTVDSQQGEFWNRGQTGANGGRKFLDPCSLQLPLASIGYRRSSQLDFQNSPSWPMASTSEVPAFEFTAEDCGGAHWLDRPEVDDGTSEEENESDSSSCRTSNSSQTLSSCHTMEPCTSDEFFQALNHAEQTFKKMENYLRHKQLCDVILVAGDRRIPAHRLVLSSVSDYFAAMFTNDVREARQEEIKMEGVEPNSLWSLIQYAYTGRLELKEDNIECLLSTACLLQLSQVVEACCKFLMKQLHPSNCLGIRSFADAQGCTDLHKVAHNYTMEHFMEVIRNQEFVLLPASEIAKLLASDDMNIPNEETILNALLTWVRHDLEQRRKDLSKLLAYIRLPLLAPQFLADMENNVLFRDDIECQKLIMEAMKYHLLPERRPMLQSPRTKPRKSTVGTLFAVGGMDSTKGATSIEKYDLRTNMWTPVANMNGRRLQFGVAVLDDKLYVVGGRDGLKTLNTVECYNPKTKTWSVMPPMSTHRHGLGVAVLEGPMYAVGGHDGWSYLNTVERWDPQARQWNFVATMSTPRSTVGVAVLSGKLYAVGGRDGSSCLKSVECFDPHTNKWTLCAQMSKRRGGVGVTTWNGLLYAIGGHDAPASNLTSRLSDCVERYDPKTDMWTAVASMSISRDAVGVCLLGDKLYAVGGYDGQAYLNTVEAYDPQTNEWTQVAPLCLGRAGACVVTVKL", "length": 755 }, "evidence": [ { "id": "HGNC:6356", "url": "https://alliancegenome.org/gene/HGNC:6356#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080424-7", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080424-7#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9C0H6-1", "protein_name": "Kelch-like protein 4", "gene_name": "KLHL4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSVSGKKEFDVKQILRLRWRWFSHPFQGSTNTGSCLQQEGYEHRGTPVQGRLKSHSRDRNGLKKSNSPVHHNILAPVPGPAPAHQRAVQNLQQHNLIVHFQANEDTPKSVPEKNLFKEACEKRAQDLEMMADDNIEDSTARLDTQHSEDMNATRSEEQFHVINHAEQTLRKMENYLKEKQLCDVLLIAGHLRIPAHRLVLSAVSDYFAAMFTNDVLEAKQEEVRMEGVDPNALNSLVQYAYTGVLQLKEDTIESLLAAACLLQLTQVIDVCSNFLIKQLHPSNCLGIRSFGDAQGCTELLNVAHKYTMEHFIEVIKNQEFLLLPANEISKLLCSDDINVPDEETIFHALMQWVGHDVQNRQGELGMLLSYIRLPLLPPQLLADLETSSMFTGDLECQKLLMEAMKYHLLPERRSMMQSPRTKPRKSTVGALYAVGGMDAMKGTTTIEKYDLRTNSWLHIGTMNGRRLQFGVAVIDNKLYVVGGRDGLKTLNTVECFNPVGKIWTVMPPMSTHRHGLGVATLEGPMYAVGGHDGWSYLNTVERWDPEGRQWNYVASMSTPRSTVGVVALNNKLYAIGGRDGSSCLKSMEYFDPHTNKWSLCAPMSKRRGGVGVATYNGFLYVVGGHDAPASNHCSRLSDCVERYDPKGDSWSTVAPLSVPRDAVAVCPLGDKLYVVGGYDGHTYLNTVESYDAQRNEWKEEVPVNIGRAGACVVVVKLP", "length": 718 }, "evidence": [ { "id": "B8JIG8", "url": "https://omabrowser.org/oma/group/B8JIG8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "B8JIG8", "url": "https://www.uniprot.org/uniprotkb/B8JIG8" } ], "pmid": "" }, { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "B8JIG8", "url": "https://www.uniprot.org/uniprotkb/B8JIG8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "B8JIG8", "url": "https://www.uniprot.org/uniprotkb/B8JIG8" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B8JIG8", "url": "https://www.uniprot.org/uniprotkb/B8JIG8" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "B8JIG8", "url": "https://www.uniprot.org/uniprotkb/B8JIG8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "B8JIG8", "url": "https://www.uniprot.org/uniprotkb/B8JIG8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" }, { "start_pos": 357, "end_pos": 359, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8JIG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JIG8" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 234, "end_pos": 301, "start_aa": "Cys", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], 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predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009299323", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299323" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q5R2", "url": "https://www.uniprot.org/uniprotkb/F1Q5R2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ftr51", "url": "https://www.uniprot.org/uniprotkb/F1Q5R2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-54", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-54", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000029105", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000029105", "database": "Bgee", "categories": [ "Gene Expression" 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"MAEARISQDEFTCPVCLDLLKHPAAIPCGHSYCKSCITDCWDQEEEKGVYSCPQCRQTFSLRPALAKNTILAEVVEKLKKTKPPADCCAGDVPCDVCTGGKYTAVKSCLVCLSSYCESHLEQHESLFKGKRHRLTEATGRLQEMICHDHDKLLEVFCRTDQKCICLLCTMDEHKNHDTVSAAAQRTESQKQMKETQSKIQERIQQRERDLQQLKEAVESHKRSAQTAVEDTKRIFTELIQHIERSRSEVTRQIRDQEKSAVSRAEEGLERMQQEINELRRTDEELEQLSEIQDPVHFLQNFQTLSASPKSTAVTDNPLRFLNSFDGMRESIQQLGQTLQNLCREELQKTSGKSSVTNTIPKTRKDFLQYSLQLTLDPNTVNEHLHLSNGNRAVNGSLKAWPYPDHPERFEELQVLCRESVCGRGYWEIEWRGDYVSIVVSYKRICRKGPGREHYFGGNDLSWSLESSNYEYTFRHNNIETELPANPLSLCHRIGVFVDHSAGTLIFYNIYRDTMSLIHSVQTTFTEPLYPGFWVYSVGTSVKLC", "length": 544, "header": "tr|F1Q5R2-1|F1Q5R2_DANRE Isoform 1 of Tripartite motif-containing protein 16 isoform X1 OS=Danio rerio OX=7955 GN=ftr51 PE=4 SV=2 CANONICAL=F1Q5R2-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PVA1-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5R2/entry#A0A8M9PVA1-1", "sequence": { "sequence": 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"glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FCG7-1", "uniprot_ac": "E7FCG7", "uniprot_id": "E7FCG7_DANRE", "mass": { "chemical_mass": 179714.0, "monoisotopic_mass": 179714.0 }, "refseq": { "ac": "XP_009295405", "name": "uncharacterized protein KIAA1755 homolog isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295405" }, "gene_names": [ { "name": "quoa", "type": "recommended", "evidence": [ { "id": "E7FCG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCG7" } ] }, { "name": "quoa", "type": "synonym", "evidence": [ { "id": "XP_009295405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295405" } ] } ], "protein_names": [ { "name": "Uncharacterized protein KIAA1755 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "E7FCG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCG7/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein KIAA1755 homolog isoform X1", "type": "synonym", "evidence": [ { "id": "XP_009295405", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295405" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_009295405.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009295405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295405" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FCG7", "url": "https://www.uniprot.org/uniprotkb/E7FCG7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "quoa", "url": "https://www.uniprot.org/uniprotkb/E7FCG7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-319", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-319", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000103586", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000103586", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00160", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00160", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13242", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13242", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100148904", "url": "https://www.ncbi.nlm.nih.gov/gene/100148904", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000219", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000219", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052231", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052231", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055251", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055251", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060650", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060650", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060651", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060651", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100148904", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148904", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVWNVAW", "url": "https://omabrowser.org/oma/group/QVWNVAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7FCG7", "url": "https://www.orthodb.org/?gene=E7FCG7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45845", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45845", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45845:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45845:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00621", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00621", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF22697", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22697", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27628", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27628", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF27632", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27632", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009295405", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009295405", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PX25", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PX25", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PX25-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PX25-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMQ9", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMQ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMQ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMQ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMR5", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMR5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IMR5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IMR5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FCG7", "url": "https://www.uniprot.org/uniprotkb/E7FCG7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FCG7-1", "url": "https://www.uniprot.org/uniprotkb/E7FCG7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-319", "url": "https://zfin.org/ZDB-GENE-090313-319", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDPECLDSCIQSCLSVLFPPFELTASTVLSQIFQLIDTQYDGDALQCLNTFLIPAKTLLEGLQQTASAPHSKRVFSSPGWPLCLQERIVIQLAPVNSLLLRPGDFYLQVVPFGIQSVQIVVKSVSEEECELEETPIPETSHSNIFTETWLQELNEKRHGRPLSRCILKTQQNIIKVPWEEVVNPEFEDERRMDSASPSNQQESSSLCRPPTPSSFSIETRICPARDGIAVSLRLVDSSSITKHSEMDQSGMRPIGWVSPSTWDSRSKSSLVGICNDPLDFTKETQGYANTWTPLLRSNGATRERSTCVRTVRFAEEPCTPCMQRKHGHGTKQKCRFMDTAITPKEKSDHPNEAETADPCGEEQIQSAYRDGLAPAVVGTSEKCHIVIQGQSNQEDRSSYFEMIPRLHVVPGKKTTTFGLVSPKLNRRRLVIKDLPQDPKSQCAPVPGSRINHPDGLTPAETERRPSRSSTPPTLKADALLHAGIVCLTGGQDRSDRAVLEVYGDHQVWISATLSSQEIFKLLLYFHTITRKGMKDVGMTVVFDARKKPPHPEFTKALLTLHEKDPGAVHCVVLLLNKDSSYSHEKRPGVTVETVTSYKALYKLVEVSQLTAALHGSLLYSHWDWIQIHQKLYPFVSDLQDASALLSGAIKKLEGVHKIDTVQDVQQCIKEQAALMKNVLEDARLVELQRGGGAMLARLRRETDVRSPHCEQSREVIDTVTHLYNGMEEQVHVLARKSNMSLQHLDFLLQLRHMEARFAQIKEWFDTEGETQLLQAESVDESSEQIQQTLQTFKAFLSEANERKHQAMMLVSDAERIQGPNYPETEVFHRMVSMFKSSVSDFVSRAERCCEELAMMVYICHICERASAVAGDCRLCLEQESLCCPADEQHWARLHAHLQRLDEFPPELLQDVRTQACALSSSRALRVWDAAWVKCEEVRRMLEERLMLLEGDQTHHGHHTDWTTGQCDATALEDEERECVPESETRANRSRDSIHNTVTCFNFRSKPRRDSKNTATTRETPADCSQRGRSSSRRAAPEQRAVSGAPVGCQWFPWQNTVNRSSSRRSELHITEPIQRHNSFSSQTHDTHGDAWRNEGENTADTHESPSRSMKLQRIMEELLLTEVEYVRSLGYILTHYYPLLSRPDVPQDLRGQRGRIFGNLEKLYDFHCQHFQQELQACQAEPLRAGRCFLNHRESFGLYALYSKNKPQSDALIQHHRYFKRKQLELGDSMDLSSYLLKPVQRISKYSLLLQEILDECVSDQSPEREEIQAALEVVRFQLRHGNDLLTMDAIRDCDLNLNEQGQLIRQDEFWVIFRKKRSLRRVFLFQDVILFTKTKKNDRGDDVYVYKLSIKTCEIGMTQSCGLSGRSFEIWFRRRRSQDTYILQAETRDIKHAWTTDLEHILWEQALKSRELRRQERLFMGTGCKPFVDIQPRNAAVNHTVNGDVTGRELVGILKTPNPLVSGLQRGGALPRPDSIGSGSTTSTAGSQSSSSSGRGSMSPSVFQGKYESLVENAGLTGCADHTCSTGRRRSSVSSLLHSRSSASPAHSIHYSSPALSRKMLSPQTEAHGTLKCQFEEPIRSKASTEV", "length": 1588, "header": "tr|E7FCG7-1|E7FCG7_DANRE Isoform 1 of Uncharacterized protein KIAA1755 homolog isoform X1 OS=Danio rerio OX=7955 GN=quoa PE=4 SV=1 CANONICAL=E7FCG7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PX25-1", "url": "https://www.uniprot.org/uniprotkb/E7FCG7/entry#A0A8M9PX25-1", "sequence": { "sequence": "MDPECLDSCIQSCLSVLFPPFELTASTVLSQIFQLIDTQYDGDALQCLNTFLIPAKTLLEGLQQTASAPHSKRVFSSPGWPLCLQERIVIQLAPVNSLLLRPGDFYLQVVPFGIQSVQIVVKSVSEEECELEETPIPETSHSNIFTETWLQELNEKRHGRPLSRCILKTQQNIIKVPWEEVVNPEFEDERRMDSASPSNQQESSSLCRPPTPSSFSIETRICPARDGIAVSLRLVDSSSITKHSEMDQSGMRPIGWVSPSTWDSRSKSSLVGICNDPLDFTKETQGYANTWTPLLRSNGATRERSTCVRTVRFAEEPCTPCMQRKHGHGTKQKCRFMDTAITPKEKSDHPNEAETADPCGEEQIQSAYRDGLAPAVVGTSEKCHIVIQGQSNQEDRSSYFEMIPRLHVVPGKKTTTFGLVSPKLNRRRLVIKDLPQDPKSQCAPVPGSRINHPDGLTPAETERRPSRSSTPPTLKADALLHAGIVCLTGGQDRSDRAVLEVYGDHQVWISATLSSQEIFKLLLYFHTITRKGMKDVGMTVVFDARKKPPHPEFTKALLTLHEKDPGAVHCVVLLLNKDSSYSHEKRPGVTVETVTSYKALYKLVEVSQLTAALHGSLLYSHWDWIQIHQKLYPFVSDLQDASALLSGAIKKLEGVHKIDTVQDVQQCIKEQAALMKNVLEDARLVELQRGGGAMLARLRRETDVRSPHCEQSREVIDTVTHLYNGMEEQVHVLARKSNMSLQHLDFLLQLRHMEARFAQIKEWFDTEGETQLLQAESVDESSEQIQQTLQTFKAFLSEANERKHQAMMLVSDAERIQGPNYPETEVFHRMVSMFKSSVSDFVSRAERCCEELAMMVYICHICERASAVAGDCRLCLEQESLCCPADEQHWARLHAHLQRLDEFPPELLQDVRTQACALSSSRALRVWDAAWVKCEEVRRMLEERLMLLEGDQTHHGHHTDWTTGQCDATALEDEERECVPESETRANRSRDSIHNTVTCFNFRSKPRRDSKNTATTRETPADCSQRGRSSSRRAAPEQRAVSGAPVGCQWFPWQNTVNRSSSRRSELHITEPIQRHNSFSSQTHDTHGDAWRNEGENTADTHESPSRSMKLQRIMEELLLTEVEYVRSLGYILTHYYPLLSRPDVPQDLRGQRGRIFGNLEKLYDFHCQHFQQELQACQAEPLRAGRCFLNHRESFGLYALYSKNKPQSDALIQHHRYFKRKQLELGDSMDLSSYLLKPVQRISKYSLLLQEILDECVSDQSPEREEIQAALEVVRFQLRHGNDLLTMDAIRDCDLNLNEQGQLIRQDEFWVIFRKKRSLRRVFLFQDVILFTKTKKNDRGDDVYVYKLSIKTCEIGMTQSCGLSGRSFEIWFRRRRSQDTYILQAETRDIKHAWTTDLEHILWEQALKSRELRRQERLFMGTGCKPFVDIQPRNAAVNHTVNGDVTGRELVGILKTPNPLVSGLQRGGALPRPDSIGSGSTTSTAGSQSSSSSGRGSMSPSVFQGKYESLVENAGLTGCADHTCSTGRRRSSVSSLLHSRSSASPAHSIHYSSPALSRKMLSPQTEAHGTLKNKETQRFENT", "length": 1583, "header": "tr|A0A8M9PX25-1|E7FCG7_DANRE Computationally mapped isoform of Uncharacterized protein KIAA1755 homolog isoform X1 OS=Danio rerio OX=7955 GN=quoa PE=4 SV=1 CANONICAL=E7FCG7-1" }, "locus": {} }, { "isoform_ac": "A0AC58IMQ9-1", "url": "https://www.uniprot.org/uniprotkb/E7FCG7/entry#A0AC58IMQ9-1", "sequence": { "sequence": "MDSASPSNQQESSSLCRPPTPSSFSIETRICPARDGIAVSLRLVDSSSITKHSEMDQSGMRPIGWVSPSTWDSRSKSSLVGICNDPLDFTKETQGYANTWTPLLRSNGATRERSTCVRTVRFAEEPCTPCMQRKHGHGTKQKCRFMDTAITPKEKSDHPNEAETADPCGEEQIQSAYRDGLAPAVVGTSEKCHIVIQGQSNQEDRSSYFEMIPRLHVVPGKKTTTFGLVSPKLNRRRLVIKDLPQDPKSQCAPVPGSRINHPDGLTPAETERRPSRSSTPPTLKADALLHAGIVCLTGGQDRSDRAVLEVYGDHQVWISATLSSQEIFKLLLYFHTITRKGMKDVGMTVVFDARKKPPHPEFTKALLTLHEKDPGAVHCVVLLLNKDSSYSHEKRPGVTVETVTSYKALYKLVEVSQLTAALHGSLLYSHWDWIQIHQKLYPFVSDLQDASALLSGAIKKLEGVHKIDTVQDVQQCIKEQAALMKNVLEDARLVELQRGGGAMLARLRRETDVRSPHCEQSREVIDTVTHLYNGMEEQVHVLARKSNMSLQHLDFLLQLRHMEARFAQIKEWFDTEGETQLLQAESVDESSEQIQQTLQTFKAFLSEANERKHQAMMLVSDAERIQGPNYPETEVFHRMVSMFKSSVSDFVSRAERCCEELAMMVYICHICERASAVAGDCRLCLEQESLCCPADEQHWARLHAHLQRLDEFPPELLQDVRTQACALSSSRALRVWDAAWVKCEEVRRMLEERLMLLEGDQTHHGHHTDWTTGQCDATALEDEERECVPESETRANRSRDSIHNTVTCFNFRSKPRRDSKNTATTRETPADCSQRGRSSSRRAAPEQRAVSGAPVGCQWFPWQNTVNRSSSRRSELHITEPIQRHNSFSSQTHDTHGDAWRNEGENTADTHESPSRSMKLQRIMEELLLTEVEYVRSLGYILTHYYPLLSRPDVPQDLRGQRGRIFGNLEKLYDFHCQHFQQELQACQAEPLRAGRCFLNHRESFGLYALYSKNKPQSDALIQHHRYFKRKQLELGDSMDLSSYLLKPVQRISKYSLLLQEILDECVSDQSPEREEIQAALEVVRFQLRHGNDLLTMDAIRDCDLNLNEQGQLIRQDEFWVIFRKKRSLRRVFLFQDVILFTKTKKNDRGDDVYVYKLSIKTCEIGMTQSCGLSGRSFEIWFRRRRSQDTYILQAETRDIKHAWTTDLEHILWEQALKSRELRRQERLFMGTGCKPFVDIQPRNAAVNHTVNGDVTGRELVGILKTPNPLVSGLQRGGALPRPDSIGSGSTTSTAGSQSSSSSGRGSMSPSVFQGKYESLVENAGLTGCADHTCSTGRRRSSVSSLLHSRSSASPAHSIHYSSPALSRKMLSPQTEAHGTLKNKETQRFENT", "length": 1392, "header": "tr|A0AC58IMQ9-1|A0AC58IMQ9_DANRE Computationally mapped isoform of Uncharacterized protein KIAA1755 homolog isoform X4 OS=Danio rerio OX=7955 GN=quoa PE=4 SV=1 CANONICAL=E7FCG7-1" }, "locus": {} }, { "isoform_ac": "A0AC58IMR5-1", "url": "https://www.uniprot.org/uniprotkb/E7FCG7/entry#A0AC58IMR5-1", "sequence": { "sequence": "MDSASPSNQQESSSLCRPPTPSSFSIETRICPARDGIAVSLRLVDSSSITKHSEMDQSGMRPIGWVSPSTWDSRSKSSLVGICNDPLDFTKETQGYANTWTPLLRSNGATRERSTCVRTVRFAEEPCTPCMQRKHGHGTKQKCRFMDTAITPKEKSDHPNEAETADPCGEEQIQSAYRDGLAPAVVGTSEKCHIVIQGQSNQEDRSSYFEMIPRLHVVPGKKTTTFGLVSPKLNRRRLVIKDLPQDPKSQCAPVPGSRINHPDGLTPAETERRPSRSSTPPTLKADALLHAGIVCLTGGQDRSDRAVLEVYGDHQVWISATLSSQEIFKLLLYFHTITRKGMKDVGMTVVFDARKKPPHPEFTKALLTLHEKDPGAVHCVVLLLNKDSSYSHEKRPGVTVETVTSYKALYKLVEVSQLTAALHGSLLYSHWDWIQIHQKLYPFVSDLQDASALLSGAIKKLEGVHKIDTVQDVQQCIKEQAALMKNVLEDARLVELQRGGGAMLARLRRETDVRSPHCEQSREVIDTVTHLYNGMEEQVHVLARKSNMSLQHLDFLLQLRHMEARFAQIKEWFDTEGETQLLQAESVDESSEQIQQTLQTFKAFLSEANERKHQAMMLVSDAERIQGPNYPETEVFHRMVSMFKSSVSDFVSRAERCCEELAMMVYICHICERASAVAGDCRLCLEQESLCCPADEQHWARLHAHLQRLDEFPPELLQDVRTQACALSSSRALRVWDAAWVKCEEVRRMLEERLMLLEGDQTHHGHHTDWTTGQCDATALEDEERECVPESETRANRSRDSIHNTVTCFNFRSKPRRDSKNTATTRETPADCSQRGRSSSRRAAPEQRAVSGAPVGCQWFPWQNTVNRSSSRRSELHITEPIQRHNSFSSQTHDTHGDAWRNEGENTADTHESPSRSMKLQRIMEELLLTEVEYVRSLGYILTHYYPLLSRPDVPQDLRGQRGRIFGNLEKLYDFHCQHFQQELQACQAEPLRAGRCFLNHRESFGLYALYSKNKPQSDALIQHHRYFKRKQLELGDSMDLSSYLLKPVQRISKYSLLLQEILDECVSDQSPEREEIQAALEVVRFQLRHGNDLLTMDAIRDCDLNLNEQGQLIRQDEFWVIFRKKRSLRRVFLFQDVILFTKTKKNDRGDDVYVYKLSIKTCEIGMTQSCGLSGRSFEIWFRRRRSQDTYILQAETRDIKHAWTTDLEHILWEQALKSRELRRQERLFMGTGCKPFVDIQPRNAAVNHTVNGDVTGRELVGILKTPNPLVSGLQRGGALPRPDSIGSGSTTSTAGSQSSSSSGRGSMSPSVFQGKYESLVENAGLTGCADHTCSTGRRRSSVSSLLHSRSSASPAHSIHYSSPALSRKMLSPQTEAHGTLKCQFEEPIRSKASTEV", "length": 1397, "header": "tr|A0AC58IMR5-1|A0AC58IMR5_DANRE Computationally mapped isoform of Uncharacterized protein KIAA1755 homolog isoform X3 OS=Danio rerio OX=7955 GN=quoa PE=4 SV=1 CANONICAL=E7FCG7-1" }, "locus": {} }, { "isoform_ac": "E7FCG7-1", "url": "https://www.uniprot.org/uniprotkb/E7FCG7/entry#E7FCG7-1", "sequence": { "sequence": "MDPECLDSCIQSCLSVLFPPFELTASTVLSQIFQLIDTQYDGDALQCLNTFLIPAKTLLEGLQQTASAPHSKRVFSSPGWPLCLQERIVIQLAPVNSLLLRPGDFYLQVVPFGIQSVQIVVKSVSEEECELEETPIPETSHSNIFTETWLQELNEKRHGRPLSRCILKTQQNIIKVPWEEVVNPEFEDERRMDSASPSNQQESSSLCRPPTPSSFSIETRICPARDGIAVSLRLVDSSSITKHSEMDQSGMRPIGWVSPSTWDSRSKSSLVGICNDPLDFTKETQGYANTWTPLLRSNGATRERSTCVRTVRFAEEPCTPCMQRKHGHGTKQKCRFMDTAITPKEKSDHPNEAETADPCGEEQIQSAYRDGLAPAVVGTSEKCHIVIQGQSNQEDRSSYFEMIPRLHVVPGKKTTTFGLVSPKLNRRRLVIKDLPQDPKSQCAPVPGSRINHPDGLTPAETERRPSRSSTPPTLKADALLHAGIVCLTGGQDRSDRAVLEVYGDHQVWISATLSSQEIFKLLLYFHTITRKGMKDVGMTVVFDARKKPPHPEFTKALLTLHEKDPGAVHCVVLLLNKDSSYSHEKRPGVTVETVTSYKALYKLVEVSQLTAALHGSLLYSHWDWIQIHQKLYPFVSDLQDASALLSGAIKKLEGVHKIDTVQDVQQCIKEQAALMKNVLEDARLVELQRGGGAMLARLRRETDVRSPHCEQSREVIDTVTHLYNGMEEQVHVLARKSNMSLQHLDFLLQLRHMEARFAQIKEWFDTEGETQLLQAESVDESSEQIQQTLQTFKAFLSEANERKHQAMMLVSDAERIQGPNYPETEVFHRMVSMFKSSVSDFVSRAERCCEELAMMVYICHICERASAVAGDCRLCLEQESLCCPADEQHWARLHAHLQRLDEFPPELLQDVRTQACALSSSRALRVWDAAWVKCEEVRRMLEERLMLLEGDQTHHGHHTDWTTGQCDATALEDEERECVPESETRANRSRDSIHNTVTCFNFRSKPRRDSKNTATTRETPADCSQRGRSSSRRAAPEQRAVSGAPVGCQWFPWQNTVNRSSSRRSELHITEPIQRHNSFSSQTHDTHGDAWRNEGENTADTHESPSRSMKLQRIMEELLLTEVEYVRSLGYILTHYYPLLSRPDVPQDLRGQRGRIFGNLEKLYDFHCQHFQQELQACQAEPLRAGRCFLNHRESFGLYALYSKNKPQSDALIQHHRYFKRKQLELGDSMDLSSYLLKPVQRISKYSLLLQEILDECVSDQSPEREEIQAALEVVRFQLRHGNDLLTMDAIRDCDLNLNEQGQLIRQDEFWVIFRKKRSLRRVFLFQDVILFTKTKKNDRGDDVYVYKLSIKTCEIGMTQSCGLSGRSFEIWFRRRRSQDTYILQAETRDIKHAWTTDLEHILWEQALKSRELRRQERLFMGTGCKPFVDIQPRNAAVNHTVNGDVTGRELVGILKTPNPLVSGLQRGGALPRPDSIGSGSTTSTAGSQSSSSSGRGSMSPSVFQGKYESLVENAGLTGCADHTCSTGRRRSSVSSLLHSRSSASPAHSIHYSSPALSRKMLSPQTEAHGTLKCQFEEPIRSKASTEV", "length": 1588, "header": "tr|E7FCG7-1|E7FCG7_DANRE Isoform 1 of Uncharacterized protein KIAA1755 homolog isoform X1 OS=Danio rerio OX=7955 GN=quoa PE=4 SV=1 CANONICAL=E7FCG7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 211, "start_aa": "Thr", "end_pos": 211, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr211", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100148904", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148904", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AB32TQS0-1", "protein_name": "Quattro isoform X1", "gene_name": "quob", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNPSSLDWSIQSALSSLFPPFEATAPTVLSQLFRTIEERYHGDALQCLLNFLIPAKHILESVQQAACAAYSDVLFQCEGWPLCLSDRVVIQLAAINPLLLRPGDFYLQVEPFGEQSARIVLKSLLVQEDLLGQENLILQAGSRVLECPTIEETPILETSYPCIFTESWLREINEGRQGNRLSRCVLSSDKGVVKVPWTEVANPEFLDRPKSNVWPDSKPCSTATIRVRDLNTEISDIESKVVVDFLPLEMETRIVPAIDGLALSVQLVESGSRLVKVNQAHTISSFAGKPVGWVSPNTWDSRQTQELEGEYVDLLEFNKEKETLVPNKIAMPMKPLGFKLVRTAQPSSKSNVSICGVDCNPNKQPSEIMQHDPDSKCRYRQSYMAALRNPVNFERASMLPCLDETRTDAGKAEPSCEGYGVGLRLQPSSCMFGQTPNQADRNPMQSFENSAQQKQSPKNSTQPSQNVPHDRKSRENADSPDQHMTQLITSMVQARQHHKSFLTGQPDLPQTVLGTKALPDKRHPCLNNAIRQDSFHMRISGQKHAKTQHLPKMGLRALPDHGGHRHDANLCLQGFSPIQHSQNQPTHITEQTPQPQISQNPFRNENSLLDCNVFCDDRHCGRGPGSPVQVIKGKSRSKSRSSLSVSETARQCLQSNKPTNRSHSDVYPEIIPMLPAIHGIKHTADLVSPKLNRPQEARKEVSLSGKAGAPVVNGVELQKLQHSDQPTTGQSVTEIQGIYISQDPTIKSLLQLGIICLPGGRDRAGRAVVEVYGGRNGWISPQVSPLELCRLLLYLHSIPRSEVRELGLTVVIDSRKCPLTSVFYKSLLMVQEQALHAVHTILMLVDKDANPRPEKHPGLQIDVVTSLKALHKTVDGHQLTSDLSGSFPYSHEDWLQFHQKLSLFQIELEAASSLLHTAIRRLDVKRTDTAKDVQSCIQEQRSSMKMVLEDTRLVALQREGGAILARMRREESRFAHSEDFRDSLESVTCLYDQVEESVHTLVMKSNQSLQHLEHVLLLRETQDSLHTIQKWCDAEERLWQKDKDDAEKTLQKIQQRLQDTQTLLRQAKENKERGMLLIKDVERKSKGTHYPETDAFRCYTTGFKTRMTGFLLKAEERKSDLQTSVDLYRFCEEASSLVKECMEYLDHMKSSNSPMSVCWSSLHAFEQRFQHFSPQHFQDRSAALLERLPDGIWMWNAVQTQCRDIRQRLSEILQAAHTHKDSQDEAQLNPVSGQTQNRAAEQGDNETLTYLQSAEGSKFEQVMTSSVHEQSASRIQQSVECTEQETRHLHETKDKLHNASSMHNESTSHAQQSVQCTVQKASMLQETNNTSRNPSMHKDSASHIQESVQCTDQNTSHLHEPQAISHHPSDRKLKEHHHKHSHSDDDLRKSGRIHKFGQTAHYKVFIRSQSAESCLRGYRYNIPLCKTDAAASCVGASLEGLSSELNQHDSFCSSASGFSQKCSSDCGSEDHGSGVRCSDNAFTKQEESVCKPECILENTSTALKLQRIMQELLQTEQEYVRALAYVVENYMPELERPDVPQDLRGQRGLIFGNLEKLRDFHQHHFIQELELCLEKPFSVGRCFLKHKESFGLYALYSKNKPRSENLLIQHGKDFFKQKQQLLKDALDLSSYLLKPVQRISKYSLLLQDLLRECECVTNAELQRTEIHTALNIIQFQLRHGNNLLAMDDIYGCDVNLKEQGQLIRQDEFLLTFRKKKCYRHIFLFQDLILFSKTRKTDVGNDTYIYKQSFKTSDIGMTHNSGDSGLCFEIWFRRRKTQDTYVLQAASREVKESWTRDLERILWEQAIHNREIRMQERVFMGIGHKPFMDIKPSEMAISDRAINCVLTGRGGVSVLRLNSIGSASGTSSSGSQSSCSSGWGSPSTSAVCPVGGDDVRYIQETSGILEEDDLDQESGNHSTLVASSESSGESVSCFSTSAHSCSSVIGGDCEHTPSELGKQHKQDHLKTTNQTRDQSGSKVQSSIGKSTEV", "length": 1988 }, "evidence": [ { "id": "HGNC:29372", "url": "https://alliancegenome.org/gene/HGNC:29372#orthology", "database": "AGR" }, { "id": "MGI:3606579", "url": "https://alliancegenome.org/gene/MGI:3606579#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5JYT7-1", "protein_name": "Uncharacterized protein KIAA1755", "gene_name": "KIAA1755", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDPPSLDTAIQHALAGLYPPFEATAPTVLGQVFRLLDSGFQGDGLSFLLDFLIPAKRLCEQVREAACAPYSHCLFLHEGWPLCLRDEVVVHLAPLNPLLLRQGDFYLQVEPQEEQSVCIMIKCLSLDLCTVDKKPVPEPAYPILFTQEWLEAINSDFEGNPLHNCLVASENGIAPVPWTKITSPEFVDDRPQVVNALCQAWGPLPLEALDLSSPQELHQASSPDNQVLPAQSLAKGKGRTYGSKYPGLIKVEQARCGEVAFRMDEVVSQDFEGDYVALLGFSQESRGESPSREAGTSSGCTSGALEEIAGTKETPLFQKILPLSEANEGPSLGNRACTKPESSEERPYNLGFRRKVNLKAPTHNSERPPQGSYMNVLEDALDCASGLRAGVSQEPAASKMQGPLGNPENMVQLRPGPRQASSPRLSPASPAAAASETKIEVKTKERNGRLPKPMPCPSRNTSSPEPPTPGLKFSFLRGQRQPSVTPEKASLQHNGPWKVLCSLYSPKPNRAKSLGKAGTTQTKTSGPATAPSPLTEEKAALPEASAGSPERGPTLEEEPPGPEPRIGALGVKVFRSRIACLPGGRDRAGRPLLLVSTTEGAWEAPWCTVSEVTKLLSYLCTIPRPEDKAKGLAVLIDARRQPPQPGLVSALQATQAQVPASIRAILFLGEKEAALQLQTLPDVQVEVLTSLKALSHHVDPSQLPAVLEGPFPYCHTEWVHFFQKLDPFLADLHQASSLLQASIEEFEKADPPGGMQEATRCLSKSKELMEAVLRDPGLLGLQREGGATLARLQHDASRLDFSPDVRSHLAAATALYSLVDEQLHVLVTASNSLLGKLELRVRLGRLEAAIHQVSDWMEQEGRRCLQSLTPKDGSLETVEKAHAEFENFFLQAAAQYRRGLELSKQAAQLGATARGAGEAERAEFPELAAFASTQRAFQAELTHFYMAAERQRTDLETLLHLHRFCKRMTWFHMDCQDLMAQLRLDKTSRVSPGDQRRLHRYLQRLASEFPAEKLAAVGLQVASLSRAGLGQELWEEARIRHEEIRMLLEKALTHSSCPEAPAAHSARPERRGVAAKGQGVSVEVTSKGRWDQPPLDSLGMDHLPKSYWPPGPPRGEQNRTFQAGSPPQEAGQAAEAEDGKGSHKLPDPAREHLLATTFFRQQPPRQSQVPRLTGGSFSSEGTDSQTSLEDSPQTSPLASL", "length": 1200 }, "evidence": [ { "id": "HGNC:29372", "url": "https://alliancegenome.org/gene/HGNC:29372#orthology", "database": "AGR" }, { "id": "MGI:3606579", "url": "https://alliancegenome.org/gene/MGI:3606579#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-319", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-319#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BWG4-1", "protein_name": "Uncharacterized protein KIAA1755 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPSALDMAIQHALAGLYPPFEATAPTVLGQVFRLLDSDFRGDGLSFLLDFLIPAKRLCEQVREAACALYTHCLFLHEGWPLCLRDEVVVHLAPLNPLLLRQGDFYLQVESWEEQSVHMTLKCLSSDLREVDKKPIPESSYSLIFTPEWLEAINNDFEGRPLHNCLVASENGITPVPWTKITSPEFVDDRPPIVKVPSSDGDSCPLEDLHLSRPQEPYQAGDLGGKGSVAQIWDKGKGKLSGDKYPGLIKVEPARSGQLAFRTDSEASQSLEGDYVALLGFPQEYRGASPDSEVVTLSVDIQKSQETRPRTKGAPLLGKTLPLSGPAGAPPLGRWACERPAGSGEKPCSGGSRRKARHKASGHTAVRQPQQPHTSVPEKLPDCTSGLVEDTEEEPAASEMQKPVGMPEAMVRLRPGPRQAFSPLLSSAGPGSPAAETKTEETTLGHGRASKPEDCLNKNASFHGSPAPGLQFSFLKEQRVPHVTPEKALLQHARPRKALCPLYSLQPCEAKAPGKDGTTLPTTSGSGPLSGEPPGFRRDSAGPPGGGLRLEECSRTKPRIETLGVKLLQSGIACLPGGRDKVGRPLLLVSTAEDAWEAPWCTTSEVAELLSYLCSVPRLEDKAKGLLVVIDARKGTQRPGLVSALQGIQALAPASVSKVLLLGEKASIPQLSVLPAQVEVLTSLKALRNHVDPSQLPEALEGPFPYHHSEWVQFFQKLDPFLTDLRQASSLLQASIQEFEKGEPPGGVQEATRCLSKSKELMETVLRDPGLLALQREGGTTLASLQQEASGLNANPDVRSHLTEAAALYNLVDGQLHDLVTASNQLLRRLELRVRLGHLETAIHQVSDWMAGEGSQSLQALAPVHVCAETVEKVHAEFEDFFLQVAAQYRQGLDLSKQAAQLGAAEEGAGEMGLPDLAAFASTQQAFQARLTHFYMAAERQRTDLETLLHLHRFRRKMSRFHMDCQNLLTQLSLGKAVKASPGDQLHLRLHCYLKRLASEFQTEKLLAMKLQVASLSRPGLGQEVWEEAQERHQEIQSLLRKALAYCPCPEVPATQVALIDRSRPVAKGQGLPREVGSKWDRSLQDSLAVDHVFKSQRTPQGEQSRNMWAGLLSPEPGQSGDTEEVRGTPKLPDPTLERLLASLFSWPHLPKQSKASRPTGGSFSSEGTGSQTSLEDSPHTSPPASL", "length": 1187 }, "evidence": [ { "id": "HGNC:29372", "url": "https://alliancegenome.org/gene/HGNC:29372#orthology", "database": "AGR" }, { "id": "MGI:3606579", "url": "https://alliancegenome.org/gene/MGI:3606579#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-319", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-319#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9WVJ6-1", "protein_name": "Protein-glutamine gamma-glutamyltransferase 2", "gene_name": "Tgm2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEELNLERCDLEIQANGRDHHTADLCQQKLVLRRGQRFRLTLYFEGRGYEASVDRLTFGAVTGPDPSEEAGTKARFSLSDDVEEGSWSASVLDQQDNVLSLQLCTPANAPVGQYRLSLETSTGYQGSSFMLGHFILLFNAWCPADDVYLDSEAERREYVLTQQGFIYQGSVKFIKSVPWNFGQFEDGILDACLMLLDVNPKFLKDRSRDCSRRSSPIYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGISPMAWIGSVDILRRWKEHGCQQVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEYGELESNKSEMIWNFHCWVESWMTRPDLQPGYEGWQAIDPTPQEKSEGTYCCGPVSVRAIKEGDLSTKYDASFVFAEVNADVVDWIRQSDGSVLKSINNSLVVGQKISTKSVGRDDREDITYTYKYPEGSPEEREVFTRANHLNKLAEKEETGVAMRIRVGDGMSLGNDFDVFAHIGNDTSESRECRLLLCARTVSYNGVLGPECGTEDINLTLDPYSENSIPLRILYEKYSGCLTESNLIKVRGLLVEPAANSYLLAERDLYLENPEIKIRILGEPKQNRKLVAEVSLKNPLSDSLYDCVFTVEGAGLTKEQKSVEVSDPVPAGDAVKVRVDLFPTDIGLHKLVVNFQCDKLKSVKGYRNIIIGPA", "length": 686 }, "evidence": [ { "id": "HGNC:29372", "url": "https://alliancegenome.org/gene/HGNC:29372#orthology", "database": "AGR" }, { "id": "MGI:3606579", "url": "https://alliancegenome.org/gene/MGI:3606579#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E7FCG7", "url": "https://www.uniprot.org/uniprotkb/E7FCG7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1058, "end_pos": 1060, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1439, "end_pos": 1441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 738, "end_pos": 740, "annotation": "n_glycosylation_sequon" }, { "start_pos": 987, "end_pos": 989, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FCG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCG7" }, { "id": "PS50010", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50010" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DH", "eco_id": "ECO_0000259", "start_pos": 1110, "end_pos": 1285, "start_aa": "Lys", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7FCG7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FCG7" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 1297, "end_pos": 1404, "start_aa": "Asn", "end_aa": "Trp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 211 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1058, "end_pos": 1060 }, { "start_pos": 1439, "end_pos": 1441 }, { "start_pos": 738, "end_pos": 740 }, { "start_pos": 987, "end_pos": 989 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F2R7-1", "uniprot_ac": "E7F2R7", "uniprot_id": "E7F2R7_DANRE", "mass": { "chemical_mass": 58676.0, "monoisotopic_mass": 58676.0 }, "refseq": { "ac": "XP_685957", "name": "microtubule-associated tyrosine carboxypeptidase 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685957" }, "gene_names": [ { "name": "kiaa0895l", "type": "recommended", "evidence": [ { "id": "E7F2R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2R7" } ] }, { "name": "kiaa0895l", "type": "synonym", "evidence": [ { "id": "XP_685957", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685957" } ] } ], "protein_names": [ { "name": "Microtubule-associated tyrosine carboxypeptidase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F2R7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2R7/entry#names_and_taxonomy" } ] }, { "name": "microtubule-associated tyrosine carboxypeptidase 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_685957", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685957" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_685957", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685957" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F2R7", "url": "https://www.uniprot.org/uniprotkb/E7F2R7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "kiaa0895l", "url": "https://www.uniprot.org/uniprotkb/E7F2R7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-220321-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-220321-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000059529", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000059529", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "562097", "url": "https://www.ncbi.nlm.nih.gov/gene/562097", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012548", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012548", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562097", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562097", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RILQPPW", "url": "https://omabrowser.org/oma/group/RILQPPW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F2R7", "url": "https://www.orthodb.org/?gene=E7F2R7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31817", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31817", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31817:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31817:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08014", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08014", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_685957", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_685957", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9Q2U2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2U2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q2U2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q2U2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G169", "url": "https://www.uniprot.org/uniprotkb/A0AC58G169", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G169-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G169-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F2R7", "url": "https://www.uniprot.org/uniprotkb/E7F2R7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F2R7-1", "url": "https://www.uniprot.org/uniprotkb/E7F2R7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-220321-2", "url": "https://zfin.org/ZDB-GENE-220321-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVLDLGENCMEQANRGGLTNNVSEMLEPEPSPEKPKPVRARTSSITQRDKAAHNGPHVPTCTSGESSSQVQRRLQKTESRNKGEQPLCRRPLSLEIKPQRVRAAQPAVQKTMKPPWRTGGPSPPMRSLTSLSLGPGNWLRRSESTCTMISSTPPRAGRAQMRPATSLPHIARGIASLPSPSTPRGPCLLVALRPVNLEQERQTFFQSDYQYEPQFEYSSPEPVSVLEKYKEGSSLFLSQAVGIMECVLRKYETYENFEEVTGGNLLPKSQVWAATRKYLQKEGCVGEVVVSLSDELLSQAVMMVERCRPTLTINLSGARQHWLEGMLRHEIGTHYLRGVNNSMQPWATSVGRKQFGLKPANPTEEGLASLHSVLLRKQPFLWRAALLYYTVYHATNMSFSQLFSHIARFVQDPAVRWEYCLRAKRGQTDTSKPGCFSKDQVYLDGILRILRHRRNIDFKILTALGKVSYEDVERLRHSAVLHGTRIPHFMQDEERYLQHLDHIVTVNELSDAELRELIP", "length": 519, "header": "tr|E7F2R7-1|E7F2R7_DANRE Isoform 1 of Microtubule-associated tyrosine carboxypeptidase 1 isoform X1 OS=Danio rerio OX=7955 GN=kiaa0895l PE=4 SV=1 CANONICAL=E7F2R7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9Q2U2-1", "url": "https://www.uniprot.org/uniprotkb/E7F2R7/entry#A0A8M9Q2U2-1", "sequence": { "sequence": "MECVLRKYETYENFEEVTGGNLLPKSQVWAATRKYLQKEGCVGEVVVSLSDELLSQAVMMVERCRPTLTINLSGARQHWLEGMLRHEIGTHYLRGVNNSMQPWATSVGRKQFGLKPANPTEEGLASLHSVLLRKQPFLWRAALLYYTVYHATNMSFSQLFSHIARFVQDPAVRWEYCLRAKRGQTDTSKPGCFSKDQVYLDGILRILRHRRNIDFKILTALGKVSYEDVERLRHSAVLHGTRIPHFMQDEERYLQHLDHIVTVNELSDAELRELIP", "length": 276, "header": "tr|A0A8M9Q2U2-1|E7F2R7_DANRE Computationally mapped isoform of Microtubule-associated tyrosine carboxypeptidase 1 isoform X1 OS=Danio rerio OX=7955 GN=kiaa0895l PE=4 SV=1 CANONICAL=E7F2R7-1" }, "locus": {} }, { "isoform_ac": "A0AC58G169-1", "url": "https://www.uniprot.org/uniprotkb/E7F2R7/entry#A0AC58G169-1", "sequence": { "sequence": "MVLDLGENCMEQANRGGLTNNVSEMLEPEPSPEKPKPVRARTSSITQRDKAAHNGPHVPTCTSGESSSQVQRRLQKTESRNKGEQPLCRRPLSLEIKPQRVRAAQPAVQKTMKPPWRTGGPSPPMRSLTSLSLGPGNWLRRSESTCTMISSTPPRAGRAQMRPATSLPHIARGIASLPSPSTPRGPCLLVALRPVNLEQERQTFFQSDYQYEPQFEYSSPEPVSVLEKYKEGSSLFLSQAVGIMECVLRKYETYENFEEVTGGNLLPKSQVWAATRKYLQKEGCVGEVVVSLSDELLSQAVMMVERCRPTLTINLSGARQHWLEGMLRHEIGTN", "length": 334, "header": "tr|A0AC58G169-1|A0AC58G169_DANRE Computationally mapped isoform of Microtubule-associated tyrosine carboxypeptidase 1 isoform X2 OS=Danio rerio OX=7955 GN=kiaa0895l PE=4 SV=1 CANONICAL=E7F2R7-1" }, "locus": {} }, { "isoform_ac": "E7F2R7-1", "url": "https://www.uniprot.org/uniprotkb/E7F2R7/entry#E7F2R7-1", "sequence": { "sequence": "MVLDLGENCMEQANRGGLTNNVSEMLEPEPSPEKPKPVRARTSSITQRDKAAHNGPHVPTCTSGESSSQVQRRLQKTESRNKGEQPLCRRPLSLEIKPQRVRAAQPAVQKTMKPPWRTGGPSPPMRSLTSLSLGPGNWLRRSESTCTMISSTPPRAGRAQMRPATSLPHIARGIASLPSPSTPRGPCLLVALRPVNLEQERQTFFQSDYQYEPQFEYSSPEPVSVLEKYKEGSSLFLSQAVGIMECVLRKYETYENFEEVTGGNLLPKSQVWAATRKYLQKEGCVGEVVVSLSDELLSQAVMMVERCRPTLTINLSGARQHWLEGMLRHEIGTHYLRGVNNSMQPWATSVGRKQFGLKPANPTEEGLASLHSVLLRKQPFLWRAALLYYTVYHATNMSFSQLFSHIARFVQDPAVRWEYCLRAKRGQTDTSKPGCFSKDQVYLDGILRILRHRRNIDFKILTALGKVSYEDVERLRHSAVLHGTRIPHFMQDEERYLQHLDHIVTVNELSDAELRELIP", "length": 519, "header": "tr|E7F2R7-1|E7F2R7_DANRE Isoform 1 of Microtubule-associated tyrosine carboxypeptidase 1 isoform X1 OS=Danio rerio OX=7955 GN=kiaa0895l PE=4 SV=1 CANONICAL=E7F2R7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:562097", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562097", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A286ZY40-1", "protein_name": "Microtubule associated tyrosine carboxypeptidase 1", "gene_name": "MATCAP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVLDSGAQVYEQAPPSPPASPSSLGHRLKPSDRDGTALYPWPQSLALPLALSVPSALRPQPELQPFSELHLGIRGHMRRSESTYTVNSTGRRGGSTQGRAPPGRGRDPGGGTLRSAASLPHIAKTRKDAGRGGSKSPCMLVALRPTNMDRERDKFFQSHYTYNPQFEYQEPMPTAVLEKYCEASGQFIHQAVGIIEAVLEKFGTYEHFEAATGGQLLTKCQIWSIVRKYMQKEGCVGEVVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNAQQPWHSAEGRLQYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHRAARMSFRQLFQDLARYVEDADVRWEYCVRAKRGQTDTSRPGCFSKDQVYLDGIVRILRHRQTIDFPLLTSLGKVSYEDVDHLRPHGVLDNTRVPHFMQDLARYRQQLEHIMATNRLDEAELGRLLPD", "length": 471 }, "evidence": [ { "id": "E7F2R7", "url": "https://omabrowser.org/oma/group/E7F2R7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "E1BJV3-1", "protein_name": "Microtubule associated tyrosine carboxypeptidase 1", "gene_name": "MATCAP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MVLDSGAQVYEQAPPSPPASPSSLAHRPGPSDQDGTALFPWPQSLALPLALSVPSALRPRAERQPFSELHLGRRGHMRRSESTYTVNSTGRRGGSTQSWAPPGRGRDPGGGTLRPAASLPHIAKARKEAGRGASKSPCMLVALRPTNMDRERDKFFQSHYTYNPQFEYQEPMPTAVLEKYCEASGQFIHQAVGIIEAVLEKFGTYEHFEAATGGQLLTKCQIWSIVRRYMQKEGCVGEVVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNARQPWHSAEGRQQYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHRAARMSFRQLFQDLARYVQDADVRWEYCVRAKRGQTDTSLPGCFSKDQVYLDGILRILRHRQTIDFPLLTSLGKVSYEDVDHLRPHGVLDNTRVPHFMQDLARYRQQLEHIMTTNRLDEAELGRLLPD", "length": 471 }, "evidence": [ { "id": "E7F2R7", "url": "https://omabrowser.org/oma/group/E7F2R7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HZK8-1", "protein_name": "Uncharacterized protein KIAA0895-like homolog", "gene_name": "Kiaa0895l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVLDSGAQVYERAPPSPPASPPSQCHRLKSSNRNGPPLYPWPQSLAMPLALAVPSTLQSQPMWKTFSQLQLRQRSHMRRSESTYNVNSTGQRGRGKTPRVCDPSGGTLRPAASLPHIAKTRKDLGNGGSKSPCMLVALRPTNMDQERDKFFQSHYTYNPQFEYQEPMPMSVLEKYQEASGQFIQQAVGIIEAVLEKFGTYEHFEAATGGQLLTKCQIWSIVRKYMQKEGCVGEVVVQLSENLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNSRQPWHSTEGRLQYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHQAAHMSFRQLFQDLAQYVQDEAVRWEYCVRAKRGQTDTSRPGCFSKDQVYLDGIVRILRHRQTIDFPLLTSLGKVSYEDVDQLRPHGILDNARVPHFMKDLGRYRQQLEYIMATNRLDEAELGRLLPD", "length": 466 }, "evidence": [ { "id": "E7F2R7", "url": "https://omabrowser.org/oma/group/E7F2R7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q4V7A9-1", "protein_name": "Microtubule-associated tyrosine carboxypeptidase 1", "gene_name": "Matcap1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVLDSGTQVYEQAPPSPPASSPSQHHKLKPSNRNGPPLYPWPQSLAMPLALAVPSALQHQTMWQTFSKLHLEQRSHMKRSESTYSVNSTGRRGRGKAPLGRGCDPGGGTLRPAASLPHIAKIRKDVVSGSNKSPCMLVALRPTNMDQEREKFFQSHYAYNPQFEYQEPMPMSVLEKYQEASGQFMHQAVGIIKAVLEKFGTYENFEAATGGQLLTKCQIWSIVRRYMQKEGCVGEVVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNSRQPWHSTEGRQQYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHQAAHMSFRQLFQDLEQYVQDEDVRWEYCVRAKRGQTDTSLPGCFSKDQVYLDGILRILRHRQTIDFQLLTSLGKVSYEDVEQLRPHGVLDKTRVPHFMKDLDRYRQQLEHIMTTNRLDEAELGRLLPD", "length": 468 }, "evidence": [ { "id": "E7F2R7", "url": "https://omabrowser.org/oma/group/E7F2R7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68EN5-1", "protein_name": "Microtubule-associated tyrosine carboxypeptidase 1", "gene_name": "MATCAP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVLDSGAQAYDQAPPSPPTSPPSLRHRLKPSDRDGPPLYPWSQSLALPLALAVPPALQPQPEQQPFSQMLLGHRGHMRRSESTYSVNSTGRRGRGTLGRPPPGRGRNPGGGTLRPAASLPHIAKTQRDAGHIASKSPCMLVALRPTNMDRERDKFFQSHYTYNPQFEYQEPMPTAVLEKYCEASGQFIHQAVGIIEAVLEKFGTYEHFEAATGGQLLTKCQIWSIVRKYMQKEGCAGEVVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNARQPWHNAEGRLRYGLRPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHRAARMSFRQLFQDLERYVQDADVRWEYCVRAKRGQTDTSLPGCFSKDQVYLDGIVRILRHRQTIDFPLLTSLGKVSYEDVDHLRPHGVLDNTRVPHFMQDLARYRQQLEHIMATNRLDEAELGRLLPD", "length": 471 }, "evidence": [ { "id": "E7F2R7", "url": "https://omabrowser.org/oma/group/E7F2R7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q810A5-1", "protein_name": "Microtubule-associated tyrosine carboxypeptidase 1", "gene_name": "Matcap1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVLDSGTQVYEQAPPRPPAGSPSQHHKLKPSNGNGPPLYPWPESLGMPLALAVPSALQQQTMWQTFSKLHLEQSSHMRRSESTYSVNSTGRRGRGKAPIGRGCDPGGTLRPAASLPHIAKIRKDVGSSSSKSPCMLVALRPTNMDQEREKFFQSHYTYNPQFEYQEPMPMSVLEKYQEASAQFMNQAVGIIEAVLEKFGTYENFEAATGGQLLTKCQIWSTVRKYMQKEGCVGEIVVQLSEDLLSQAVMMVENSRPTLAINLTGARQYWLEGMLRHEIGTHYLRGVNNSRQPWHSTEGRLQYGLQPANPTEEGLASLHSVLFRKQPFLWRAALLYYTIHQAAHMSFRQLFQDLAQYVQDEGVRWEYCVRAKRGQTDTSQPGCFSKDQVYLDGILRILRHRHTIDFQLLTSLGKVSYEDVEQLRPYGVLDNTRVPHFMKDLERYRQQLEHIMTTNRLDEAELGRLLPD", "length": 467 }, "evidence": [ { "id": "E7F2R7", "url": "https://omabrowser.org/oma/group/E7F2R7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E7F2R7", "url": "https://www.uniprot.org/uniprotkb/E7F2R7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metallopeptidase activity", "id": "GO:0008237", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008237", "evidence": [ { "database": "UniProtKB", "id": "E7F2R7", "url": "https://www.uniprot.org/uniprotkb/E7F2R7" } ], "pmid": "" }, { "name": "carboxypeptidase activity", "id": "GO:0004180", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004180", "evidence": [ { "database": "UniProtKB", "id": "E7F2R7", "url": "https://www.uniprot.org/uniprotkb/E7F2R7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 314, "end_pos": 316, "annotation": "n_glycosylation_sequon" }, { "start_pos": 340, "end_pos": 342, "annotation": "n_glycosylation_sequon" }, { "start_pos": 396, "end_pos": 398, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 21, "end_pos": 23 }, { "start_pos": 314, "end_pos": 316 }, { "start_pos": 340, "end_pos": 342 }, { "start_pos": 396, "end_pos": 398 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F133-1", "uniprot_ac": "E7F133", "uniprot_id": "E7F133_DANRE", "mass": { "chemical_mass": 64832.0, "monoisotopic_mass": 64832.0 }, "refseq": { "ac": "XP_002663472", "name": "cilia- and flagella- associated protein 210 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663472" }, "gene_names": [ { "name": "cfap210", "type": "recommended", "evidence": [ { "id": "E7F133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F133" } ] }, { "name": "cfap210", "type": "synonym", "evidence": [ { "id": "XP_002663472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663472" } ] } ], "protein_names": [ { "name": "Cilia- and flagella- associated protein 210 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F133", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F133/entry#names_and_taxonomy" } ] }, { "name": "cilia- and flagella- associated protein 210 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002663472", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663472" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_002663472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663472" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F133", "url": "https://www.uniprot.org/uniprotkb/E7F133" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cfap210", "url": "https://www.uniprot.org/uniprotkb/E7F133", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-457", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-457", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077928", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077928", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "559457", "url": "https://www.ncbi.nlm.nih.gov/gene/559457", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039986", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039986", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043597", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043597", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:559457", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559457", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EMHFRSQ", "url": "https://omabrowser.org/oma/group/EMHFRSQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F133", "url": "https://www.orthodb.org/?gene=E7F133", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28663", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28663", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28663:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28663:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13868", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13868", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002663472", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002663472", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9Q5A4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q5A4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q5A4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F133", "url": "https://www.uniprot.org/uniprotkb/E7F133", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F133-1", "url": "https://www.uniprot.org/uniprotkb/E7F133-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-457", "url": "https://zfin.org/ZDB-GENE-081104-457", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSTVTSITGVVKYGRRKGSSKQAVNSEMEKTGANLRQVVVLSKSEWQRLQDSVNGINHHNRSVMAAAEQREALHKRSKDIVKNWSNTIAGQRQKKLEAKKIREAIEEEERKLIDIEEAKYQAQMRKEAIEKAKTQMYYQTDRVKGFHGALMLAEVLKEREAQIELKRMKQNATKDIDRDMLAEMASREEQALLEEQKKALQKKQEHQAIVESLKQQIVDHELEKEQERQEVKREAEEIERLRNLHLWEQAMKERKKQGEKRSILKAHRDLLTNREMMKATEAQKLQEEEEKCKQLASHKEKMMKMRKEKQEEIFRELQRHRETIIQKLAVQKQQLISNEEEIIAKAVSEREERLTREQQEKEKKHTDMLNAIAAHRESMRQEQERKVEEEKQKALEMLNAKKEADQIFMEKQQRRAQKAREEGKTLQDLYIQEMAEKRAKHQRTKKDQQEFVEKSNAFIIEEEKQFQTYAKQVIETAERAGRNTYPLIKAAREGIGGGLGPVFGGLRPSYLVHDESGVQMPSYLNSRTQNIKELNETSDIQQSKKRLGFTW", "length": 551, "header": "tr|E7F133-1|E7F133_DANRE Isoform 1 of Cilia- and flagella- associated protein 210 isoform X1 OS=Danio rerio OX=7955 GN=cfap210 PE=1 SV=1 CANONICAL=E7F133-1" }, "isoforms": [ { "isoform_ac": "A0A8M9Q5A4-1", "url": "https://www.uniprot.org/uniprotkb/E7F133/entry#A0A8M9Q5A4-1", "sequence": { "sequence": "MCVAVNSEMEKTGANLRQVVVLSKSEWQRLQDSVNGINHHNRSVMAAAEQREALHKRSKDIVKNWSNTIAGQRQKKLEAKKIREAIEEEERKLIDIEEAKYQAQMRKEAIEKAKTQMYYQTDRVKGFHGALMLAEVLKEREAQIELKRMKQNATKDIDRDMLAEMASREEQALLEEQKKALQKKQEHQAIVESLKQQIVDHELEKEQERQEVKREAEEIERLRNLHLWEQAMKERKKQGEKRSILKAHRDLLTNREMMKATEAQKLQEEEEKCKQLASHKEKMMKMRKEKQEEIFRELQRHRETIIQKLAVQKQQLISNEEEIIAKAVSEREERLTREQQEKEKKHTDMLNAIAAHRESMRQEQERKVEEEKQKALEMLNAKKEADQIFMEKQQRRAQKAREEGKTLQDLYIQEMAEKRAKHQRTKKDQQEFVEKSNAFIIEEEKQFQTYAKQVIETAERAGRNTYPLIKAAREGIGGGLGPVFGGLRPSYLVHDESGVQMPSYLNSRTQNIKELNETSDIQQSKKRLGFTW", "length": 532, "header": "tr|A0A8M9Q5A4-1|E7F133_DANRE Computationally mapped isoform of Cilia- and flagella- associated protein 210 isoform X1 OS=Danio rerio OX=7955 GN=cfap210 PE=1 SV=1 CANONICAL=E7F133-1" }, "locus": {} }, { "isoform_ac": "E7F133-1", "url": "https://www.uniprot.org/uniprotkb/E7F133/entry#E7F133-1", "sequence": { "sequence": "MSTVTSITGVVKYGRRKGSSKQAVNSEMEKTGANLRQVVVLSKSEWQRLQDSVNGINHHNRSVMAAAEQREALHKRSKDIVKNWSNTIAGQRQKKLEAKKIREAIEEEERKLIDIEEAKYQAQMRKEAIEKAKTQMYYQTDRVKGFHGALMLAEVLKEREAQIELKRMKQNATKDIDRDMLAEMASREEQALLEEQKKALQKKQEHQAIVESLKQQIVDHELEKEQERQEVKREAEEIERLRNLHLWEQAMKERKKQGEKRSILKAHRDLLTNREMMKATEAQKLQEEEEKCKQLASHKEKMMKMRKEKQEEIFRELQRHRETIIQKLAVQKQQLISNEEEIIAKAVSEREERLTREQQEKEKKHTDMLNAIAAHRESMRQEQERKVEEEKQKALEMLNAKKEADQIFMEKQQRRAQKAREEGKTLQDLYIQEMAEKRAKHQRTKKDQQEFVEKSNAFIIEEEKQFQTYAKQVIETAERAGRNTYPLIKAAREGIGGGLGPVFGGLRPSYLVHDESGVQMPSYLNSRTQNIKELNETSDIQQSKKRLGFTW", "length": 551, "header": "tr|E7F133-1|E7F133_DANRE Isoform 1 of Cilia- and flagella- associated protein 210 isoform X1 OS=Danio rerio OX=7955 GN=cfap210 PE=1 SV=1 CANONICAL=E7F133-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:559457", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559457", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0L0L6-1", "protein_name": "Cilia and flagella associated protein 210", "gene_name": "Cfap210", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQVRYGRRSGKAKERAGMESYEKEEIPYPPLLPSTVDLQQVTIIPHAEWERIRDSLNKLTREAAVLRAERTAKKNMHMKSQELVKHWTNTYAGMKEQKLRAKQKRDEELEAERQILDLEEEIYKQGERKKAIENAKQYQFYQTERVKRFHSGLLLSRVMKERDVQIQYKKNAVKSDEKWEEQVKLNDAKALKEDQEKLEKQRRERVALAKDHLKQIKEHEEEEETRKKSEEKDAEEIKRQNLLYEIEMKKKLSRKQEEIDASRKRFFDNMRDKNIIRAVEQQQQEEEEEKTRKFIKAKKRLIQMRKDKEAETHRLMEERRERINNFLSKLIKEKLDTEDLIMSRDIADIDTELDKREKEKHEKMQADLKAIAEHRASVMKNKEEEEKQRKIESKEELQAVLKADKMFQELEKEKKLKANKEKLEVQDAHIHQIALNKFNSKQLKEEDLNYWRLTEALAVEKEKEFEKYAREVINFESESTKKYTYPMVKAVQEGVGGGRGPPFVGRGGIRPSYQANDVTGVQLPFYNSQGSKYDFQKSKRRLGFTW", "length": 546 }, "evidence": [ { "id": "MGI:1923100", "url": "https://alliancegenome.org/gene/MGI:1923100#orthology", "database": "AGR" }, { "id": "HGNC:25064", "url": "https://alliancegenome.org/gene/HGNC:25064#orthology", "database": "AGR" }, { "id": "E7F133", "url": "https://omabrowser.org/oma/group/E7F133/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0JLY1-1", "protein_name": "Cilia- and flagella- associated protein 210", "gene_name": "Cfap210", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQVRFGRRSGQAKESQGMDCFEKEEIPYPPLLPSKVDLQQITIIPHAEWERIRDSLNRLTREAAVLRAERAAKKKMHVKSQELVKHWTNTYAGMKEQKLKAKQKRDEEIEAERKVLDLEEEIYKEGERKKAIESARQCQFHQTERVKRFHSGLLLSRVMKERDVQIQYKKNAVKSDKKWEEQVKLNDEKAFKEDQEKEEKRRRERVALAEDHLKQIEEHKEEEEARKKSEEKDAEEMKRQNLLYEIEMKKNLSKKQEEIDTNRKLLLDNMHNKNIIRAVEQQQQEEEDEKIRKFIKAKKRLIQMRMDKDAETHRLMEERRERINNFLSKLIKEKLDTEDLIIARDISEADAELEKREKEKHEKNQADLKAIAEYRASVMKNKEEEERQRKIEAKEQLQAVLKADKIFQELEKEKSLKVTREKLEIQDAHIQQIAINKYNAKQMKEEELDYWRLTDALTVEKEKEFEKYAREVINFESESTKKYAYPMVKAVQEGVGGGRGPPFVGRGGIRPSYQATDATGVQLPCFKSQGSKYNDFQKSKRRLGFTW", "length": 547 }, "evidence": [ { "id": "MGI:1923100", "url": "https://alliancegenome.org/gene/MGI:1923100#orthology", "database": "AGR" }, { "id": "HGNC:25064", "url": "https://alliancegenome.org/gene/HGNC:25064#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-457", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-457#orthology", "database": "AGR" }, { "id": "E7F133", "url": "https://omabrowser.org/oma/group/E7F133/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E1BJL9-1", "protein_name": "Cilia- and flagella- associated protein 210", "gene_name": "CFAP210", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLVRFGRRSGQAKESAEMKNCEEDPVLYPPLLPTKVDLRQVTIIPHNEWERIRDSLDSLTREAACLRAERKAKKEMHLRSQEVVKHWTNTYAGMKEQKLEAKKKRDEEIEAERQILDIEEAIYKQGERKKAIELAKQYQFYQTERVKNFHSGLLLSRVMKERDAQIEFQKSKIKSDKKWEEQVKLNVEKAFKEEREKAEKQRRERVALAKDHLKQIKEHEEEEERRRKEEEKDAEEIKRQNSLYEIEMKKKQGKKKEEINESRRLFFEHLNDKHIIKAVEQQQQEEEDEKIRKFIKAKKRLTQMGKEKEAETHRLMEERRKRINNFLSKLMKEKFDNEDLIIARDIAEAEAEWEKREREKYEKNKAELKAIAEHRALVMKNKEEEERQRKIEATEQMLAILKADQIFWEHEKEKKQKADKERREVQDAHIQQMAKHKFNALQAKQAESEYCRLTEALVAEKEKEFQDYAREVIESESESTKKYIYPLVKAVQEGPGGGRGPVLVDRGGLRPSYQANDTTGVQLPFYNSPGSKYNNFQKSKGRLGFTW", "length": 547 }, "evidence": [ { "id": "E7F133", "url": "https://omabrowser.org/oma/group/E7F133/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1S1V4-1", "protein_name": "Cilia and flagella associated protein 210", "gene_name": "CFAP210", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGTSEVVVRFGRRCGRAKEITEIKNYEEDQVLYPPLLPDKVDLRQVTIIPHNEWERIRDSLDSLTREAAHLRAKRKAKKEMHFRSQEVVKHWTNTYAGMRKQKLEAKKKRDEEIEAERQILDVEEAIYKQGERKKAIEYAKQYQFYQTERVKNFHSGLLLSRVMKERDAQIEFQKSKIKSDKKWEEQLKLNIEKGFKEEQEKAEKQRRDRLALAKDHLKQIKEHEEEEVRRRKQEEKDAEEIKQQNLLYEIEMKKKLGMKKEKINESRRLFFEHLNDKNVIKAIERQQQEEEDEKIRKFIKAKKRLTQMGKEKEAETHRLMEERRERINNFLSKLMKEKFDNEDLIIARDIAEAEAEWEKREREKHEKNKAELKAIAEHRAVVMNNKEEEERRRKIEAKEQLLAILKADQIFWEHEKEKKRKADKERREVQDAHIQQMAKNKFKVKQAKQAELEDCRLTEALIAEKEKEFQDYAREVIELESKSTNKYMHPLVKAVQEGPGGGHGPVFVDRGGLRPSYQVNDITGVQLPFYNSQGSKYNNFQKSKGRLGFTW", "length": 552 }, "evidence": [ { "id": "E7F133", "url": "https://omabrowser.org/oma/group/E7F133/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3GU88-1", "protein_name": "Coiled-coil domain-containing protein 173", "gene_name": "Ccdc173", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQARFGRRSAQSKESTGMKNTERDEIPYPPLLPSKVDLNQVTIIPHAEWERIRDSLDRLTREAAALRAERTAKKKIHVQSQELVKHWTNTYAGMKEQKLKAKQKRDEELEAERQILDLEEEIYKQGERKKAIENAKQYQFYQTERVKSFHSGLLLSRVMKERDAQIQFKKNSVKSDKKWEEQVKLDVEKALKEEKEKEEKRRRERYALAEDHLKQIKEHKEEEQERKKNEEKDAEEIKRQNLLYEIEMKKKLSKKQEEINKNRKRFFDHMHDKSIIQAVEQQQQEEEDEKIRKFIKAKKCLLQMRKDKEAETHRLIEERRERINNFLSELMKEKLDSEDLFIVKDVTEAEAELEKREKEKYEKKQAELKAIADHRASVMKNKEEEEKQRKIDSKEQLLAVMKADKIFKELEKEKKLKANKEKQEIQDAYVQQMALNKFNAKQSKEEELSYWNLTEALAAEKEKEFQKYAREVIESESESAKKYTYPLIRAVQEGVGGGRGPPFAGRGGIRPSYQTQDFTGVQLPFFNSQRSKYNDFQKSKKRLGFTW", "length": 547 }, "evidence": [ { "id": "E7F133", "url": "https://omabrowser.org/oma/group/E7F133/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q0VFZ6-1", "protein_name": "Cilia- and flagella- associated protein 210", "gene_name": "CFAP210", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDTSSEMLVRFGRRCGRAKESTEIRNSEEDQVLYLPLLPSKVDLQQVTIIPHDEWKRIQDSLDRLTREAACLRAERKAKKEMHLRSQEVVKHWTNTYAGMKEQKLEAKKKRDEEIEAERQILDLEEEIYKQGKRKKAIENAKQYQFYQTERVKNFHSGLLLSRVMKERDAQIEFRKSKIKSDKKWEEQLKLNIEKAFKEEQEKAEKRHRERVALAKDHLKQIKEHEEEEERRKKYEEKDAEEIKRQNALYEIEMRKKLEKKREEMHESRRRFLEHMQDKHIIKAVEQQQQEEEDEKMRKFIKAKKRLIQMGKEKEAETHRLMEKRRERIHNFLSELLKEKLDNEDMIIARDIAEAEAEWEKREREKDEKNKAELKTIAEYRAIVMKNKEEEERQRKIEAKEQLLAVMKADQIFWEHEKEKKCKADKEHQEVQDAHIQQMAKNKFNAKQAKQAELDYCRLTEALVAEKEKEFQDYAREVIELESETTNKYIYPLVKAVQEGPGGGRGPVFVDRGGLRPSYQANDVTGVQLPFYNSQGPKYNFQKSKRRLGFTW", "length": 552 }, "evidence": [ { "id": "MGI:1923100", "url": "https://alliancegenome.org/gene/MGI:1923100#orthology", "database": "AGR" }, { "id": "HGNC:25064", "url": "https://alliancegenome.org/gene/HGNC:25064#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-457", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-457#orthology", "database": "AGR" }, { "id": "E7F133", "url": "https://omabrowser.org/oma/group/E7F133/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "axonemal microtubule", "id": "GO:0005879", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005879", "evidence": [ { "database": "UniProtKB", "id": "E7F133", "url": "https://www.uniprot.org/uniprotkb/E7F133" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 60, "end_pos": 62, "annotation": "n_glycosylation_sequon" }, { "start_pos": 83, "end_pos": 85, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FE82-1", "uniprot_ac": "E7FE82", "uniprot_id": "E7FE82_DANRE", "mass": { "chemical_mass": 14274.0, "monoisotopic_mass": 14274.0 }, "refseq": { "ac": "NP_001314752", "name": "ninjurin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314752" }, "gene_names": [ { "name": "ninj2", "type": "recommended", "evidence": [ { "id": "E7FE82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FE82" } ] }, { "name": "ninj2", "type": "synonym", "evidence": [ { "id": "NP_001314752", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314752" } ] } ], "protein_names": [ { "name": "Ninjurin-2", "type": "synonym", "evidence": [ { "id": "E7FE82", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FE82/entry#names_and_taxonomy" } ] }, { "name": "ninjurin-2", "type": "synonym", "evidence": [ { "id": "NP_001314752", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314752" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH461098.1, EH435099.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH435099.1 and EH461098.1. On May 26, 2016 this sequence version replaced XP_001339643.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001314752", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314752" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FE82", "url": "https://www.uniprot.org/uniprotkb/E7FE82" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ninj2", "url": "https://www.uniprot.org/uniprotkb/E7FE82", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100422-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100422-19", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000079824", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000079824", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "799267", "url": "https://www.ncbi.nlm.nih.gov/gene/799267", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007007", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007007", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:799267", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799267", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PNFYGRR", "url": "https://omabrowser.org/oma/group/PNFYGRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7FE82", "url": "https://www.orthodb.org/?gene=E7FE82", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12316", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12316", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12316:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12316:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001314752", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314752", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9Q638", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q638", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9Q638-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9Q638-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FE82", "url": "https://www.uniprot.org/uniprotkb/E7FE82", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FE82-1", "url": "https://www.uniprot.org/uniprotkb/E7FE82-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100422-19", "url": "https://zfin.org/ZDB-GENE-100422-19", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPAATGRTDPQPTEPLNMNHYATKKSVAESMLDVALLMANASQLKAVLEQGPEFRYYLTVIILIGASLFFQVLAGALFVNMARKNLNNVANQRKLDIMNNVATGLVFLTVIINIFITAFGVQKTGLYPKQ", "length": 130, "header": "tr|E7FE82-1|E7FE82_DANRE Isoform 1 of Ninjurin-2 OS=Danio rerio OX=7955 GN=ninj2 PE=3 SV=1 CANONICAL=E7FE82-1" }, "isoforms": [ { "isoform_ac": "A0A8M9Q638-1", "url": "https://www.uniprot.org/uniprotkb/E7FE82/entry#A0A8M9Q638-1", "sequence": { "sequence": "MPAATGRTDPQPTEPLNMNHYATKKSVAESMLDVALLMANASQLKAVLEQGPEFRYYLTVIILIGASLFFQVLAGALFVNMARKNLNNVANQRKLDIMNNVATGLVFLTVIINIFITAFGVQKTESQ", "length": 127, "header": "tr|A0A8M9Q638-1|E7FE82_DANRE Computationally mapped isoform of Ninjurin-2 OS=Danio rerio OX=7955 GN=ninj2 PE=3 SV=1 CANONICAL=E7FE82-1" }, "locus": {} }, { "isoform_ac": "E7FE82-1", "url": "https://www.uniprot.org/uniprotkb/E7FE82/entry#E7FE82-1", "sequence": { "sequence": "MPAATGRTDPQPTEPLNMNHYATKKSVAESMLDVALLMANASQLKAVLEQGPEFRYYLTVIILIGASLFFQVLAGALFVNMARKNLNNVANQRKLDIMNNVATGLVFLTVIINIFITAFGVQKTGLYPKQ", "length": 130, "header": "tr|E7FE82-1|E7FE82_DANRE Isoform 1 of Ninjurin-2 OS=Danio rerio OX=7955 GN=ninj2 PE=3 SV=1 CANONICAL=E7FE82-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. 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"" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 40, "end_pos": 42 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F9D9-1", "uniprot_ac": "E7F9D9", "uniprot_id": "E7F9D9_DANRE", "mass": { "chemical_mass": 67877.0, "monoisotopic_mass": 67877.0 }, "refseq": { "ac": "XP_002664303", "name": "uncharacterized protein tcof1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664303" }, "gene_names": [ { "name": "tcof1", "type": "recommended", "evidence": [ { "id": "E7F9D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F9D9" } ] }, { "name": "tcof1", "type": "synonym", "evidence": [ { "id": "XP_002664303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664303" } ] } ], "protein_names": [ { "name": "Uncharacterized protein tcof1 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F9D9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F9D9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein tcof1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002664303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664303" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_002664303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664303" } ] } ], "disease": [ { "disease_id": "DOID:0080789", "recommended_name": { "id": "DOID:0080789", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080789", "name": "Treacher Collins syndrome 1", "description": "A Treacher Collins syndrome that has_material_basis_in heterozygous mutation in the 'treacle' gene (TCOF1) on chromosome 5q32." }, "synonyms": [ { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "Treacher Collins syndrome 1", "description": "Any Treacher-Collins syndrome in which the cause of the disease is a mutation in the TCOF1 gene." }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "TCOF1 Treacher-Collins syndrome", "description": "" }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "Treacher Collins syndrome type 1", "description": "" }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "Treacher-Collins syndrome 1", "description": "" }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "Treacher-Collins syndrome caused by mutation in TCOF1", "description": "" }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "TCS1", "description": "" }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "TREACHER COLLINS syndrome 1", "description": "" }, { "id": "MIM:154500", "resource": "MIM", "url": "https://www.omim.org/entry/154500", "name": "Treacher Collins syndrome 1", "description": "Treacher Collins syndrome 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080789", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080789" } ] }, { "disease_id": "DOID:2908", "recommended_name": { "id": "DOID:2908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2908", "name": "Treacher Collins syndrome", "description": "A syndrome that is characterized by bilateral and symmetric downslanting palpebral fissures, malar hypoplasia, micrognathia, and external ear abnormalities." }, "synonyms": [ { "id": "DOID:2908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2908", "name": "Franceschetti syndrome", "description": "" }, { "id": "DOID:2908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2908", "name": "mandibulofacial dysostosis", "description": "" }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "Treacher Collins syndrome 1", "description": "Any Treacher-Collins syndrome in which the cause of the disease is a mutation in the TCOF1 gene." }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "TCOF1 Treacher-Collins syndrome", "description": "" }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "Treacher Collins syndrome type 1", "description": "" }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "Treacher-Collins syndrome 1", "description": "" }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "Treacher-Collins syndrome caused by mutation in TCOF1", "description": "" }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "TCS1", "description": "" }, { "id": "MONDO:0007944", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007944", "name": "TREACHER COLLINS syndrome 1", "description": "" }, { "id": "MIM:154500", "resource": "MIM", "url": "https://www.omim.org/entry/154500", "name": "Treacher Collins syndrome 1", "description": "Treacher Collins syndrome 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "2908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2908" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F9D9", "url": "https://www.uniprot.org/uniprotkb/E7F9D9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tcof1", "url": "https://www.uniprot.org/uniprotkb/E7F9D9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141219-12", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141219-12", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000087555", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000087555", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100329277", "url": "https://www.ncbi.nlm.nih.gov/gene/100329277", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006594", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006594", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100329277", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100329277", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QVNTVHT", "url": "https://omabrowser.org/oma/group/QVNTVHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F9D9", "url": "https://www.orthodb.org/?gene=E7F9D9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "XP_002664303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664303", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9QB70", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QB70", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QB70-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QB70-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F9D9", "url": "https://www.uniprot.org/uniprotkb/E7F9D9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F9D9-1", "url": "https://www.uniprot.org/uniprotkb/E7F9D9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-141219-12", "url": "https://zfin.org/ZDB-GENE-141219-12", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSNITDASQSELINLIYHHLKDNGYKKAARSLRKHAPQVETNKVKASLTDIFKKWASSDDDAPPVPSGVQTPELKSPVKRKTGAGAKSKNTSPSAGKKPASSKKTSGSGNKSQKEKTKGSKKKKEPKKTKVLPCVDVSAIASVSAAPGNDSDSDTSLDLEKWRKVASQLSDADRAKMDVLSILDESVVSTTRKSTAKRKPRQPAKAKKDPKPANKGKSSTPVKTNNTAKPEDVPAASTPQSDESKSEDAAVISQVKTPPKKTVKKLNSSVSGIDVAEAAHSVQNKTNISGGSDSEGIKSPKKVHFKLSDSVSEQCESPKIAQTENGTSETPSIVETPSKKHKKKKSQPEAGDAETSLDIKEGTNGSSKALSEETNAEQSETLSRKVKKSKKSKNVDETLKTDVSSVIESADSSCKKDELMVNEELEEPVQSETPSKKAKAKKVKSSEDPGELETPLKRTKTDADVLQSDSTNNSLKKKKKKSKTAADGVEIQNEISPDGNEDTSSQEVKTTKKKKHKIEEEEAAVEEEQEEEEAEPKKKKKKKKVKEDEDAEPALQTPEEEEAASVPALVNPKKKKKKKGKEREAAEEDDASPVSAPPEEVQIPKKKKKSSKEKQLSNEEDHGLNST", "length": 628, "header": "tr|E7F9D9-1|E7F9D9_DANRE Isoform 1 of Uncharacterized protein tcof1 isoform X1 OS=Danio rerio OX=7955 GN=tcof1 PE=1 SV=2 CANONICAL=E7F9D9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9QB70-1", "url": "https://www.uniprot.org/uniprotkb/E7F9D9/entry#A0A8M9QB70-1", "sequence": { "sequence": "MSSNITDASQSELINLIYHHLKDNGYKKAARSLRKHAPQVETNKVKASLTDIFKKWASSDDDAPPVPSGKKPASSKKTSGSGNKSQKEKTKGSKKKKEPKKTKVLPCVDVSAIASVSAAPGNDSDSDTSLDLEKWRKVASQLSDADRAKMDVLSILDESVVSTTRKSTAKRKPRQPAKAKKDPKPANKGKSSTPVKTNNTAKPEDVPAASTPQSDESKSEDAAVISQVKTPPKKTVKKLNSSVSGIDVAEAAHSVQNKTNISGGSDSEGIKSPKKVHFKLSDSVSEQCESPKIAQTENGTSETPSIVETPSKKHKKKKSQPEAGDAETSLDIKEGTNGSSKALSEETNAEQSETLSRKVKKSKKSKNVDETLKTDVSSVIESADSSCKKDELMVNEELEEPVQSETPSKKAKAKKVKSSEDPGELETPLKRTKTDADVLQSDSTNNSLKKKKKKSKTAADGVEIQNEISPDGNEDTSSQEVKTTKKKKHKIEEEEAAVEEEQEEEEAEPKKKKKKKKVKEDEDAEPALQTPEEEEAASVPALVNPKKKKKKKGKEREAAEEDDASPVSAPPEEVQIPKKKKKSSKEKQLSNEEDHGLNST", "length": 600, "header": "tr|A0A8M9QB70-1|E7F9D9_DANRE Computationally mapped isoform of Uncharacterized protein tcof1 isoform X1 OS=Danio rerio OX=7955 GN=tcof1 PE=1 SV=1 CANONICAL=E7F9D9-1" }, "locus": {} }, { "isoform_ac": "E7F9D9-1", "url": "https://www.uniprot.org/uniprotkb/E7F9D9/entry#E7F9D9-1", "sequence": { "sequence": "MSSNITDASQSELINLIYHHLKDNGYKKAARSLRKHAPQVETNKVKASLTDIFKKWASSDDDAPPVPSGVQTPELKSPVKRKTGAGAKSKNTSPSAGKKPASSKKTSGSGNKSQKEKTKGSKKKKEPKKTKVLPCVDVSAIASVSAAPGNDSDSDTSLDLEKWRKVASQLSDADRAKMDVLSILDESVVSTTRKSTAKRKPRQPAKAKKDPKPANKGKSSTPVKTNNTAKPEDVPAASTPQSDESKSEDAAVISQVKTPPKKTVKKLNSSVSGIDVAEAAHSVQNKTNISGGSDSEGIKSPKKVHFKLSDSVSEQCESPKIAQTENGTSETPSIVETPSKKHKKKKSQPEAGDAETSLDIKEGTNGSSKALSEETNAEQSETLSRKVKKSKKSKNVDETLKTDVSSVIESADSSCKKDELMVNEELEEPVQSETPSKKAKAKKVKSSEDPGELETPLKRTKTDADVLQSDSTNNSLKKKKKKSKTAADGVEIQNEISPDGNEDTSSQEVKTTKKKKHKIEEEEAAVEEEQEEEEAEPKKKKKKKKVKEDEDAEPALQTPEEEEAASVPALVNPKKKKKKKGKEREAAEEDDASPVSAPPEEVQIPKKKKKSSKEKQLSNEEDHGLNST", "length": 628, "header": "tr|E7F9D9-1|E7F9D9_DANRE Isoform 1 of Uncharacterized protein tcof1 isoform X1 OS=Danio rerio OX=7955 GN=tcof1 PE=1 SV=2 CANONICAL=E7F9D9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100329277", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100329277", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A206-1", "protein_name": "Treacle ribosome biogenesis factor 1", "gene_name": "Tcof1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEARKRRELLPLIYHHLLQAGYVRAAREVKEQSGQKNFLTHPVTLLDIYTHWQQTSELGLKQKAENDETLQAKKSRVSDPISSSESSEEEEEEAETGTAKATPRPTPVNSTAAALPSNMKQKAKTKTANKTVNSVLPPASGKTAVQLLSGKSPKKSAEPLASIVLASETEEEGSAQVLGPTAKPGMVSAGQASSSSEDTSSSSDETDVEVKPSTKPQAKAPVTPAKDPPARTASGPTKLGDVTPASARAAATKAAESESSEEDSESEDEAPAGLPSQVTTPGKGLHVRAASVSAKGMSRKGPISATPEKTGPITPQAKTGRPQKDMETSSEDDSDSEDEMPVTVTTPQARPSGKSPQVRGTSAPAKESSQKGAPAVTPGKTRPVAAQAQAGKPETRSSEESESDSGETPAAGTLTTSPAKVKPLGKSPQVRPASTANLGSSRKGANPPCLGKVGSAVLKVQTGKEEEDSESSSEESDSDGAVNAAKAKPPGRKATPALPRKTGPVATQVKTDKGKDHAESSEESTDSEEEAAPAASAAQAKPAPIKQMKASPRKGTAASTTGASASSPRKAGTKTSSASLSSLALPKGTQKPDVDSSSEWESEGAAPGTTGVQGKSGGKGLQGRAASGQGVAPLHAQKTGPSGAQVKATAQEDSESSEEESSSEEEDETPAQVMALGRLPPAKANPPPTKTPLASASGKAAAVVPPPKGKAPASTVQNSTISARGQRAVPATGKAGAPATQAQKGPMAGTGEDSESSSEEESDSEEETPAQVKPVGKTSQVRAASAPVKESPNKGAYSGTSRKTGPPATQAQTGKTEDSESSSEESDSDREIPPAITPAQDGISQSTRSKLSGLAPPEKSTEESSESSDEDLPSGQAIKSPPISVNPNRGPAAPVPTPEQHQAVNTRKAQASGSTAQSSSSESEDEDMIPATQPPTLAIRTNVTTPTALSQTAAQPSKSEQSSRMPKGKKPKTASTQISSAMEALPVTLPQSTPAQSKTTNKLGDPKLAEKQQLTPGYPKAPRSSEDSSDTSSESEEDAKRPQMSKSSQRLDPDASQKETVVEETPTESSDDEMVAPSQSLLSGYVTPGLTVANSQPSKATPRPDANPLVSSAPATKDNPDGKQKSKSQDSTADTTLRKTGRKEASSGSTPQKPKKPKKSTLSSPAPAQTLPNSITQRLLEQPWPLSEAQVQASVMKVLTELLEQERQKATEAIKESGKKGQKRKLSGDQVEAGAPKNKKKKQQLAAGTSAGSPEKASRTSKAKSKLNKGSAGGKGKGSPVPQGAKEKPEGKLGIKLESGEQSDPKSKKEKKKSSKKKKDKEKKEKKKGKKTPAKDSASPVQKKKKKKKKTAEPAV", "length": 1357 }, "evidence": [ { "id": "MGI:892003", "url": "https://alliancegenome.org/gene/MGI:892003#orthology", "database": "AGR" }, { "id": "HGNC:11654", "url": "https://alliancegenome.org/gene/HGNC:11654#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O08784-1", "protein_name": "Treacle protein", "gene_name": "Tcof1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEARKRRELLPLIYHHLLQAGYVRAAREVKEQSGQKSFLTQPVTLLDIYTHWQQTSELGQKQKAEDDETLQAKKSRVSDPVSSSESSDQEKEEEAATERAKATPRPTPVNSATAALPSKVKEKGKTKTANKTVNSVSHPGSGKTVVHLLSGKSPKKSAEPLANTVLASETEEEGNAQALGPTAKSGTVSAGQGSSSSEDSSISSDETDVEVKSPAKPAQAKASAAPAKDPPARTAPGPTKLGNVAPTPAKPARAAAAAAAAAVAAAAAAAAEESESSEEDSDSEDEAPAGLPSQVKASGKGPHVRADSVSAKGISGKGPILATPGKTGPAATQAKAERPEKDSETSSEDDSDSEDEMPVTVNTPQARTSGKSPRARGTSAPAKESSQKGAPAVTPGKARPVAAQAGKPEAKSSEESESDSGETPAAATLTTSPAKVKPLGKSSQVRPVSTVTPGSSGKGANLPCPGKVGSAALRVQMVKKEDVSESSSAELDSDGPGSPAKAKASLALPQKVRPVATQVKTDRGKGHSGSSEESSDSEEEAAPAASAAQAKPALEKQMKASSRKGTPASATGASTSSHCKAGAVTSSASLSSPALAKGTQRSDVDSSSESESEGAAPSTPRVQGKSGGKGLQGKAALGQGVAPVHTQKTGPSVKAMAQEDSESLEEDSSSEEEDETPAQATPLGRLPQAKANPPPTKTPPASASGKAVAAPTKGKPPVPNSTVSARGQRSVPAAGKAGAPATQAQKGPVAGTGEDSESSSKEESDSEEETPAQIKPVGKTSQVRAASAPAKESPKKGAHPGTPGKTGSSATQAQPGKTEDSDSSSEESDSDTEMPSAQAIKSPPVSVNRNSSPAVPAPTPEGVQAVNTTKKASGTTAQSSSSESEDGDEDLIPATQPSTYALRTSVTTPAALSRAASQPSKSEQSSRMPKGKKAKAAASAQTSSAVETLPMMPPQSAPIQPKATNKLGKSKLPEKQQLAPGYPKAPRSSEDSSDTSSEDEEDAKRPQMPKSAHRLDPDPSQKETVVEETPTESSEDEMVAPSQSLLSGYMTPGLTVANSQASKATPRPDSNSLASSAPATKDNPDGKQKSKSQHAADTALPKTGRKEASSGSTPQKPKKLKKSTSSSPAPTQTLPNSITQRLLEQAWPLSEAQVQASVVKVLTELLEQERLKATEAIKESGKKSQKRKLSGDLEAGAPKNKKKKEQPVPRASAVSPEKAPMTSKAKSKLDKGSAGGKGKGSPGPQGAKEKPDGELLGIKLESGEQSDPKSKSKKKKSLKKKKDKEKKEKKKGKKSLAKDSASPIQKKKKKKKKSAEPAV", "length": 1320 }, "evidence": [ { "id": "MGI:892003", "url": "https://alliancegenome.org/gene/MGI:892003#orthology", "database": "AGR" }, { "id": "HGNC:11654", "url": "https://alliancegenome.org/gene/HGNC:11654#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141219-12", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141219-12#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q13428-1", "protein_name": "Treacle protein", "gene_name": "TCOF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEARKRRELLPLIYHHLLRAGYVRAAREVKEQSGQKCFLAQPVTLLDIYTHWQQTSELGRKRKAEEDAALQAKKTRVSDPISTSESSEEEEEAEAETAKATPRLASTNSSVLGADLPSSMKEKAKAETEKAGKTGNSMPHPATGKTVANLLSGKSPRKSAEPSANTTLVSETEEEGSVPAFGAAAKPGMVSAGQADSSSEDTSSSSDETDVEGKPSVKPAQVKASSVSTKESPARKAAPAPGKVGDVTPQVKGGALPPAKRAKKPEEESESSEEGSESEEEAPAGTRSQVKASEKILQVRAASAPAKGTPGKGATPAPPGKAGAVASQTKAGKPEEDSESSSEESSDSEEETPAAKALLQAKASGKTSQVGAASAPAKESPRKGAAPAPPGKTGPAVAKAQAGKREEDSQSSSEESDSEEEAPAQAKPSGKAPQVRAASAPAKESPRKGAAPAPPRKTGPAAAQVQVGKQEEDSRSSSEESDSDREALAAMNAAQVKPLGKSPQVKPASTMGMGPLGKGAGPVPPGKVGPATPSAQVGKWEEDSESSSEESSDSSDGEVPTAVAPAQEKSLGNILQAKPTSSPAKGPPQKAGPVAVQVKAEKPMDNSESSEESSDSADSEEAPAAMTAAQAKPALKIPQTKACPKKTNTTASAKVAPVRVGTQAPRKAGTATSPAGSSPAVAGGTQRPAEDSSSSEESDSEEEKTGLAVTVGQAKSVGKGLQVKAASVPVKGSLGQGTAPVLPGKTGPTVTQVKAEKQEDSESSEEESDSEEAAASPAQVKTSVKKTQAKANPAAARAPSAKGTISAPGKVVTAAAQAKQRSPSKVKPPVRNPQNSTVLARGPASVPSVGKAVATAAQAQTGPEEDSGSSEEESDSEEEAETLAQVKPSGKTHQIRAALAPAKESPRKGAAPTPPGKTGPSAAQAGKQDDSGSSSEESDSDGEAPAAVTSAQVIKPPLIFVDPNRSPAGPAATPAQAQAASTPRKARASESTARSSSSESEDEDVIPATQCLTPGIRTNVVTMPTAHPRIAPKASMAGASSSKESSRISDGKKQEGPATQVSKKNPASLPLTQAALKVLAQKASEAQPPVARTQPSSGVDSAVGTLPATSPQSTSVQAKGTNKLRKPKLPEVQQATKAPESSDDSEDSSDSSSGSEEDGEGPQGAKSAHTLGPTPSRTETLVEETAAESSEDDVVAPSQSLLSGYMTPGLTPANSQASKATPKLDSSPSVSSTLAAKDDPDGKQEAKPQQAAGMLSPKTGGKEAASGTTPQKSRKPKKGAGNPQASTLALQSNITQCLLGQPWPLNEAQVQASVVKVLTELLEQERKKVVDTTKESSRKGWESRKRKLSGDQPAARTPRSKKKKKLGAGEGGEASVSPEKTSTTSKGKAKRDKASGDVKEKKGKGSLGSQGAKDEPEEELQKGMGTVEGGDQSNPKSKKEKKKSDKRKKDKEKKEKKKKAKKASTKDSESPSQKKKKKKKKTAEQTV", "length": 1488 }, "evidence": [ { "id": "MGI:892003", "url": "https://alliancegenome.org/gene/MGI:892003#orthology", "database": "AGR" }, { "id": "HGNC:11654", "url": "https://alliancegenome.org/gene/HGNC:11654#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141219-12", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141219-12#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 150, "end_pos": 152, "annotation": "n_glycosylation_sequon" }, { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 285, "end_pos": 287, "annotation": "n_glycosylation_sequon" }, { "start_pos": 288, "end_pos": 290, "annotation": "n_glycosylation_sequon" }, { "start_pos": 326, "end_pos": 328, "annotation": "n_glycosylation_sequon" }, { "start_pos": 365, "end_pos": 367, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 4, "end_pos": 6, "annotation": "n_glycosylation_sequon" }, { "start_pos": 626, "end_pos": 628, "annotation": "n_glycosylation_sequon" }, { "start_pos": 91, "end_pos": 93, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 150, "end_pos": 152 }, { "start_pos": 226, "end_pos": 228 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 285, "end_pos": 287 }, { "start_pos": 288, "end_pos": 290 }, { "start_pos": 326, "end_pos": 328 }, { "start_pos": 365, "end_pos": 367 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 4, "end_pos": 6 }, { "start_pos": 626, "end_pos": 628 }, { "start_pos": 91, "end_pos": 93 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E9QHV0-1", "uniprot_ac": "E9QHV0", "uniprot_id": "E9QHV0_DANRE", "mass": { "chemical_mass": 76678.0, "monoisotopic_mass": 76678.0 }, "refseq": { "ac": "XP_021334567", "name": "kelch-like protein 9 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334567" }, "gene_names": [ { "name": "si:rp71-68n21.9", "type": "recommended", "evidence": [ { "id": "E9QHV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QHV0" } ] }, { "name": "si:rp71-68n21.9", "type": "synonym", "evidence": [ { "id": "XP_021334567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334567" } ] } ], "protein_names": [ { "name": "Kelch-like protein 9 isoform X1", "type": "synonym", "evidence": [ { "id": "E9QHV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QHV0/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 9 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021334567", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334567" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021334567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334567" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QHV0", "url": "https://www.uniprot.org/uniprotkb/E9QHV0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:rp71-68n21.9", "url": "https://www.uniprot.org/uniprotkb/E9QHV0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081105-100", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-100", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000067751", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000067751", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18239", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18239", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100151173", "url": "https://www.ncbi.nlm.nih.gov/gene/100151173", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100151173", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100151173", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NEWTFVN", "url": "https://omabrowser.org/oma/group/NEWTFVN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9QB93", "url": "https://www.orthodb.org/?gene=A0A8M9QB93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E9QHV0", "url": "https://www.orthodb.org/?gene=E9QHV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45632:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45632:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_021334567", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021334567", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9QB93", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QB93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QB93-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QB93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QHV0", "url": "https://www.uniprot.org/uniprotkb/E9QHV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QHV0-1", "url": "https://www.uniprot.org/uniprotkb/E9QHV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081105-100", "url": "https://zfin.org/ZDB-GENE-081105-100", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGNSGEEGKLHRRLSRIGSRSQREPPRPPPQTEKPPAAVPPRPAEATPKPPEPAPKPVVIPPKPTVPQKPVAPPKPQIQVFNSTEHGADILKGLDHFRGDETLCDVTLVPGDSSETFPVHRVIMASASDYFKAMFTGGMREQELKEIKLHGVSTVGLKNIIVFIYTSQLSLSLGTLQDTLEAASFLQVLPVLNFCNQLLSSEITIENCVEVERIAKDLLLEDVQKHIHTFVCENFSMLMQSGRLLQLSEASMTFALSSNSLRGLSEMELYRIARAWLSHKPNERRSAAYSLMRHIRFPLMSPAELLQISQEDQTEEGAASKRKEEGEAFMRSDTACVNLLLEASNYQMLPFLQPALQTERTKIRSDCTHLVVLGGVMRQQLVVSKELKLYNKDDGGSWRALQPMEVPRYQHGVALLGGFLYIVGGQSTYDTKGKTAVDSAYRYDPRFDRWLQVASLNEKRTFFHLSALKGKLYAVGGRNATGEIDSVECYNLNKNEWTLVAPMSEPHYGHAGTVHGGLMYVSGGITRDAFQKELLCYNPDRDVWSRRADMMELRGLHCMCTVGERLYVMGGNHFRGTNDYDDVLSCEFYSPDADQWTMVAPMPRGQSDVGVAVFEERIYVVGGYSWNSRCMVDIVQCYDPEKDEWEKAFSLLEPLGGIRACTMTVHCPQGSADETDIQECPLSTSK", "length": 686, "header": "tr|E9QHV0-1|E9QHV0_DANRE Isoform 1 of Kelch-like protein 9 isoform X1 OS=Danio rerio OX=7955 GN=si:rp71-68n21.9 PE=4 SV=1 CANONICAL=E9QHV0-1" }, "isoforms": [ { "isoform_ac": "A0A8M9QB93-1", "url": "https://www.uniprot.org/uniprotkb/E9QHV0/entry#A0A8M9QB93-1", "sequence": { "sequence": "MGGEEGKLHRRLSRIGSRSQREPPRPPPQTEKPPAAVPPRPAEATPKPPEPAPKPVVIPPKPTVPQKPVAPPKPQIQVFNSTEHGADILKGLDHFRGDETLCDVTLVPGDSSETFPVHRVIMASASDYFKAMFTGGMREQELKEIKLHGVSTVGLKNIIVFIYTSQLSLSLGTLQDTLEAASFLQVLPVLNFCNQLLSSEITIENCVEVERIAKDLLLEDVQKHIHTFVCENFSMLMQSGRLLQLSEASMTFALSSNSLRGLSEMELYRIARAWLSHKPNERRSAAYSLMRHIRFPLMSPAELLQISQEDQTEEGAASKRKEEGEAFMRSDTACVNLLLEASNYQMLPFLQPALQTERTKIRSDCTHLVVLGGVMRQQLVVSKELKLYNKDDGGSWRALQPMEVPRYQHGVALLGGFLYIVGGQSTYDTKGKTAVDSAYRYDPRFDRWLQVASLNEKRTFFHLSALKGKLYAVGGRNATGEIDSVECYNLNKNEWTLVAPMSEPHYGHAGTVHGGLMYVSGGITRDAFQKELLCYNPDRDVWSRRADMMELRGLHCMCTVGERLYVMGGNHFRGTNDYDDVLSCEFYSPDADQWTMVAPMPRGQSDVGVAVFEERIYVVGGYSWNSRCMVDIVQCYDPEKDEWEKAFSLLEPLGGIRACTMTVHCPQGSADETDIQECPLSTSK", "length": 684, "header": "tr|A0A8M9QB93-1|E9QHV0_DANRE Computationally mapped isoform of Kelch-like protein 9 isoform X1 OS=Danio rerio OX=7955 GN=si:rp71-68n21.9 PE=4 SV=1 CANONICAL=E9QHV0-1" }, "locus": {} }, { "isoform_ac": "E9QHV0-1", "url": "https://www.uniprot.org/uniprotkb/E9QHV0/entry#E9QHV0-1", "sequence": { "sequence": "MGNSGEEGKLHRRLSRIGSRSQREPPRPPPQTEKPPAAVPPRPAEATPKPPEPAPKPVVIPPKPTVPQKPVAPPKPQIQVFNSTEHGADILKGLDHFRGDETLCDVTLVPGDSSETFPVHRVIMASASDYFKAMFTGGMREQELKEIKLHGVSTVGLKNIIVFIYTSQLSLSLGTLQDTLEAASFLQVLPVLNFCNQLLSSEITIENCVEVERIAKDLLLEDVQKHIHTFVCENFSMLMQSGRLLQLSEASMTFALSSNSLRGLSEMELYRIARAWLSHKPNERRSAAYSLMRHIRFPLMSPAELLQISQEDQTEEGAASKRKEEGEAFMRSDTACVNLLLEASNYQMLPFLQPALQTERTKIRSDCTHLVVLGGVMRQQLVVSKELKLYNKDDGGSWRALQPMEVPRYQHGVALLGGFLYIVGGQSTYDTKGKTAVDSAYRYDPRFDRWLQVASLNEKRTFFHLSALKGKLYAVGGRNATGEIDSVECYNLNKNEWTLVAPMSEPHYGHAGTVHGGLMYVSGGITRDAFQKELLCYNPDRDVWSRRADMMELRGLHCMCTVGERLYVMGGNHFRGTNDYDDVLSCEFYSPDADQWTMVAPMPRGQSDVGVAVFEERIYVVGGYSWNSRCMVDIVQCYDPEKDEWEKAFSLLEPLGGIRACTMTVHCPQGSADETDIQECPLSTSK", "length": 686, "header": "tr|E9QHV0-1|E9QHV0_DANRE Isoform 1 of Kelch-like protein 9 isoform X1 OS=Danio rerio OX=7955 GN=si:rp71-68n21.9 PE=4 SV=1 CANONICAL=E9QHV0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 65, "start_aa": "Thr", "end_pos": 65, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr65", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100151173", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100151173", "resource": "KEGG Pathway" }, { "id": "R-DRE-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-DRE-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A140-1", "protein_name": "Kelch-like family member 13", "gene_name": "Klhl13", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDILHRGELVAAILRNRSLVEEEDQHLKLCLGSEMGLSSHLQSCKAGSTRIFTSNSHSSVVLQGFDQLRLDGLLCDVTLMPGDTDDAYPVHRVMMASASDYFKAMFTGGMKEQELMCIKLHGVSRVGLRKIIDFIYTAKLSLNMDTLQDTLEAASFLQILPVLDFCKVFLISGVTLDNCVEVGRIANTYHLTEVDKYVNSFVLKNFAALLSTGEFLKLPFERLAFVLSSNSLKRCTELELFKATCRWLRLEEPRMDVAAKLMKNIRFPLMTPQELINYVQTVDFMRTDNTCVNLLLEASNYQMMPFMQPVMQSDRTAIRSDTTHLVTLGGVLRQQLVVSKELRMYDEKTHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWIQVASLNEKRTFFHLSALKGFLYAVGGRNAAGELPTVECYNPRTNEWTYVAKMNEPHYGHAGTVYGGVMYISGGITHDTFQKELMCFDPDTDKWIQKAPMTTVRGLHCMCTVGDRLYVIGGNHFRGTSDYDDVLSCEYYSPILDQWTPIASMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKNEWHKVFDLPESLGGIRACTLTVYPPEENTPSPSRESPLSGP", "length": 638 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M3ASV8-1", "protein_name": "Kelch-like protein 31", "gene_name": "klhl43", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPKKKSARPKKAIPEVTTVESGVLVPEPNVKKLELPLNVEQLNRLNGVPLPPPVIRPGEKGFGLGTELTRPLHGSALLEELSRMRQERFLTDMELACKTKAFDVHKLVISSVSQYLREVLAKDPGLKRLELPTLSPLGLANVITFAYLGRVHMSLYTIGCTVSAASTLQIPHLLQMCMDFLMAELNTHTCVYVWNIGAAYGLMPVRDAARRYILENFAQFSETTQFNQLTFEQITAFLQDDNLILPSEVSTFQIAMKWLDFDPKRQEHAAELLSHVRFETIPASELVSEIQPVPRMMLDPQCHRLLVDAMNYHLLPYQQNTLQSRRTKVRGSQNALLTIGGRPSLTERALSREVLWRDPREGTATWRHLTQLPAKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVGTLSRYDPRFNTWLHLTSMRQRRTHFSLVATNGRLYAIGGRNTDGLLATIESYQPSTNTWQLRTPMDMPRCCHSSAVLPSGDILVTGGYVNCAYSRSVIQYSIDRDAWSEKGELETPRGWHCSALLAGKVYVVGGSQLGAGGVRIDVMTMEVYSSESQEWSRAANLPIGVSTAGMSPIGSHLYILGGWNEAEKRYKSAVQRYDPGTDSWAAVEDLPEPIVGVSCCALGLPPRHTSRRHRNTPSHEDHSSVTLQNNTA", "length": 665 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LIM8-1", "protein_name": "Kelch-like family member 26", "gene_name": "Klhl26", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTFSTFNPTSAGSARCPGLGLRVRAPLHRSGARRKMAESGGSSGSGQSPERPSSLADRNGALKCTFSAAGHSTGLLQGLAALRAQGQLLDVVLTVNSEAFHAHKVVLAACSDYFRAMFTGGMREASQAVIQLQGVSARGLRHIIDFAYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCEDFLKAAMSVETCLHIGQMATTFSLTSLRESVDAFTFRHFLQIAAEEDFLRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPARRARASLVLRHVRFPLMQPAELVDSVQTLDVMLDDALCRQYLLEAFSYHVLPCRQHDMQSPRTAVRSDVASLVAFGGTPYTDSDRAVSSKVFQLPEPGARHFRELTEMELGCSHAGVAVLDNFVYVAGGQHLQHRSGEGAVDACYRYDPQRNRWLRLRALRESRVQFQLTALGGLLYATGGRNRAGSLASVERYCPRRDSWDFACPLKRRTWGHAGAAAAGRLYISGGYGVSAEDKKALQCYDPAADRWEPRAPMREPRVLHAMLGAAGRIYALGGRMDHVDRCFDVLAVEYYVPDADQWTSVTPMRAGQSEAGCCLLERKIYIVGGYNWRLNNVTGIVQVYNTETDEWERDLHFPESFAGIACAAVLLPRSGHGR", "length": 641 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2AAX3-1", "protein_name": "Kelch-like protein 15", "gene_name": "Klhl15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGDVEGFCSSIHDTSVSAGFRALYEEGLLLDVTLVIEDHQFQAHKALLATQSDYFRIMFTADMRERDQDKIHLKGLTATGFSHVLQFMYYGTIELSMNTVHEILQAAMYVQLIEVVKFCCSFLLAKICLENCAEIMRLLDDFGVNIEGVREKLDAFLLDNFVPLMSRPDFLSYLSFEKLMSYLDNDHLSRFPEIELYEAVQSWLRHDRRRWRHTDTIIQNIRFCLMTPSSVFEKVKTSEFYRYSRQLRYEVDQALNYFQNVHQQPLLDMKSSRIRSAKPQTTVFRGMIGHSMVNSKILLLKKPRVWWELEGPQVPLRPDCLAIVNNFVFLLGGEELGPDGEFHASSKVFRYDPRQNSWLRMADMSVPRSEFAVGVIGKFIYAVAGRTRDETFYSTERYDITNDKWEFVDPYPVNKYGHEGTVLNNKLFITGGITSSSTSKQVCVFDPSKEGTIEQRTRRTQVVTNCWENKSKMNYARCFHKMISYNGKLYVFGGVCVILRASFESQGCPSTEVYNPDTDQWTILASMPIGRSGHGVTVLDKQIMVLGGLCYNGHYSDSILTFDPDENKWKEDEYPRMPCKLDGLQVCNLHFPDYVLDEVRRCN", "length": 604 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZA50-1", "protein_name": "Kelch-like protein 15", "gene_name": "Klhl15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGDVEGFCSSIHDTSVSAGFRALYEEGLLLDVTLVIEDHQFQAHKALLATQSDYFRIMFTADMRERDQDKIHLKGLTATGFSHVLQFMYYGTIELSMNTVHEILQAAMYVQLIEVVKFCCSFLLAKICLENCAEIMRLLDDFGVNIEGVREKLDAFLLDNFVPLMSRPDFLSYLSFEKLMSYLDNDHLSRFPEIELYEAVQSWLRHDRRRWRHTDTIIQNIRFCLMTPSSVFEKVKTSEFYRYSRQLRYEVDQALNYFQNVHQQPLLDMKSSRIRSAKPQTTVFRGMIGHSMVNSKILLLKKPRVWWELEGPQVPLRPDCLAIVNNFVFLLGGEELGPDGEFHASSKVFRYDPRQNSWLRMADMSVPRSEFAVGVIGKFIYAVAGRTRDETFYSTERYDITNDKWEFVDPYPVNKYGHEGTVLNNKLFITGGITSSSTSKQVCVFDPSKEGTIEQRTRRTQVVTNCWENKSKMNYARCFHKMISYNGKLYVFGGVCVILRASFESQGCPSTEVYNPDTDQWTILASMPIGRSGHGVTVLDKQIMVLGGLCYNGHYSDSILTFDPDENKWKEDEYPRMPCKLDGLQVCNLHFPDYVLDEVRRCN", "length": 604 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZLT6-1", "protein_name": "Kelch-like protein 31", "gene_name": "Klhl31", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPKKKTLKKNKPEINEMTIIVEDSPLNKLNALNGLLGGENSLSCVSSELTDTSYGPNLLEGLSKMRQESFLCDLVIGTKTKSFDVHKSVMASCSEYFYNILKNDPSTKRVDLNDIAPLGLATVIAYAYTGKLTLSLYTIGSIISAAVYLQIHTLVKMCSDFLIREISVENCMYVVNMAETYCLKNAKATAQKFIRDNFIEFADSEQFMKLTFEQINELLIDDDLQLPSELVAFQIAMKWIEFDQKRVKHAADLLSNIRFGTISAQDLVNYVQTVPRMMQDADCHKLLVDAMNYHLLPYHQNTLQSRRTRIRGGCRVLITVGGRPGLTEKSLSRDVLYRDPENGWSKLTEMPAKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLGSMNQKRTHFSLSVFNGLLYAVGGRNAEGSLASLECYVPSTNQWQPKAPLEVARCCHASAVADGRVIVTGGYIGSAYSRSVCAYDPALDAWQELPGLSTPRGWHCSVALGDRVYVMGGSQLGPRGERVDVLTVESFSPVARQWSFVAPLPVGVSTAGVSALHGRAYLVGGWNEGEKKYKKCIQCFNPELNEWMEDDELPEATVGVSCCTLAMPNSVSRESRASSVSSVPVSI", "length": 634 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q503R4-1", "protein_name": "Kelch-like protein 36", "gene_name": "klhl36", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEIGKQTRLSRPHRLSESSKVYRWADQANNLLQGLNEQRQHGQMCDVVLVADDQRIPAHRALLAVSSPYFQAMFTLGMREEHESEIELVGASYVGVKAVIDFLYSGNLPLDGGNIDYVLETAHLLQVWQAVDFCCQYLEKEVREDNYLYLQELALLYSLDRLDAFIDRFILKHFSTLAITSEFLQDVRMFKLCAYLSSEQVQCLNEETLFEVAFKWLKQKPERLEFALQLLSNIRFALIPFYLLKYYVLPNLHSLLPLDTSCKVLVEEAIDYHRKLSAQPVMQTQRTGLRGGVECLLLLGGEVSERGEGLSAEVCWLDEEAGKWVEETKMPAPRSQHCVAVLGGFIFTAGGSCSPDNGGDSASDMLYRYDPRRCHWIKGAPMNQRRVDFYLGTMGECLIAVGGRNDSGPLSSVEVYHPADDHWTYVAELPKFTYGHAGTIHKGIVYISGGHDYQIGPYRHDMLSYDPKTADAWNECQAMILARGWHSMASLEDRIYAIGGSDDHEDSMERFDVLEVEAFDPQTNQWTMIAPLRYASSEAGLAVLNRKIYVLGGYSWETMDFSQGTQVFDPDKEQWTLGPNLPKHIAGPSCVCLIEPELIDSIDTE", "length": 605 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q53HC5-1", "protein_name": "Kelch-like protein 26", "gene_name": "KLHL26", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAESGGSSGGAGGGGAFGAGPGPERPNSTADKNGALKCTFSAPSHSTSLLQGLATLRAQGQLLDVVLTINREAFPAHKVVLAACSDYFRAMFTGGMREASQDVIELKGVSARGLRHIIDFAYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCEEFLKAAMSVETCLNIGQMATTFSLASLRESVDAFTFRHFLQIAEEEDFLRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPARRPRASHVLCHIRFPLMQSSELVDSVQTLDIMVEDVLCRQYLLEAFNYQVLPFRQHEMQSPRTAVRSDVPSLVTFGGTPYTDSDRSVSSKVYQLPEPGARHFRELTEMEVGCSHTCVAVLDNFVYVAGGQHLQYRSGEGAVDACYRYDPHLNRWLRLQAMQESRIQFQLNVLCGMVYATGGRNRAGSLASVERYCPRRNEWGYACSLKRRTWGHAGAASGGRLYISGGYGISVEDKKALHCYDPVADQWEFKAPMSEPRVLHAMVGAGGRIYALGGRMDHVDRCFDVLAVEYYVPETDQWTSVSPMRAGQSEAGCCLLERKIYIVGGYNWRLNNVTGIVQVYNTDTDEWERDLHFPESFAGIACAPVLLPRAGTRR", "length": 615 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5RGB8-1", "protein_name": "Kelch-like protein 26", "gene_name": "klhl26", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAESDGVEFFANRAQSSMADNKNSVLRCTFSAPSHSSTLLRGLSALRDQGQLLDVVLAIDNERFEVHKAVLASCSDYFRAMFTGGMKESNQNTIELIGLSARGLKHIIDFAYSSEVTLDLDCIQDVLGAAVFLQMVPVVELCEEFLKSAMSVETCLNIGQMATTFSLSSLKQSVDAYTFRHFLQIAQEDDFLHIPMERLTFFLQSNKLKNCSEIDLFHAAIRWLQHDASRRTVASEVLCHVRFPLMRSSELVDSVQIVDIMVEDVQCRHFLLEAFNYQILPFRQHEMQSPRTSIRSDITSLITFGGTPYTDNDRTVSSKVYFLPDITVRQFKELTEMEMGCSHACVSVLDNFVYVVGGQHLQYRSGEGAVDICFRYDPHLNQWLRIQPMQESRIQFQLNVLDGQLYATGGRNRSGSLSSVECYCPKKNEWTNVDSLKRRIWGHAGATCGDKLYISGGYGVSVEDKKTLHCYDSALDQWDFKCPMNEPRVLHAMISANNRIYALGGRMDHVDRCFDVLAVEYYIPETDQWTTVSPMRAGQSEAGCCLLDKKIYIVGGYNWHLNNVTSIVQVYNTETDEWERDLHFPESFAGIACTPIILPQTTTQR", "length": 605 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6DEL7-1", "protein_name": "Kelch-like protein 15", "gene_name": "klhl15", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGDVEVYLSQVHDGSVSSGFRALYEERLLLDVTLLIEEHHFQAHKALLATQSDYFRVMFTADMRERDQDKIHMKGLTAAGFGHVLRFMYYGSLELSMLTVQEILQAAMYVQLTEAVEFCCSFLLAKICLENCAEVMRLLEDFSVGVEGVQEQLDAFLLENFVPLMARPDFLSYLSLEKLMAYLDSDQLSRYPEIELYEAVQAWLRHDRRRWRHTDAVVQNLRFCLMTPANIFEKVKTSEFYRYSRQLRLEVDQALSYFHQVNEQPLAETKSNRIRSVRPQTAVFRGMIGHSMVNSKILLLHRPKVWWELEGPQVPLRPDCLAIVNNFAFLLGGEELGPDGEFHASSKVYRYDPRQNSWLRMADMSVPRSEFAVGVIGKYIYAVAGRTRDETFYSTERYDIVEDKWEFVDPYPVNKYGHEGTVLNGKLYITGGITSSSTSKQVCVFDPGREGSSEHRTRRTPILTNCWENKSKMNYARCFHKMISHNGKLYVFGGVCVILRASFESQGCPSTEVYDPETDEWTILASMPIGRSGHGVAVLDKQIMVLGGLCYNGHYSDSILTFDPEENKWKEDEYPRMPCKLDGLQVCSLHFPEYVLEHVRRCS", "length": 604 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6Q7X9-1", "protein_name": "Kelch-like protein 31", "gene_name": "klhl31", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAPKKNKAAKKSKADINEMTIMVEDSPSNKINGLNTLLEGGNGFSCISTEVTDPVYAPNLLEGLGHMRQDSFLCDLTVATKSKSFDVHKVVMASCSEYIQNMLRKDPSLKKIELSDLSPVGLATVITYAYSGKLTLSLYTIGSTISAALLLQIHTLVKMCSDFLMRETSVENCMYVVNIADTYNLKETKEAAQKFMRENFIEFSEMEQFLKLTYEQINEFLTDDSLQLPSELTAFQIAVKWLDFDEKRLKYAPDLLSNIRFGTITPQDLVSHVQNVPRMMQDAECHRLLVDAMNYHLLPFQQNILQSRRTKVRGGLRVLLTVGGRPALTEKSLSKDILYRDEDNVWNKLTEMPAKSFNQCVAVLDGFLYVAGGEDQNDARNQAKHAVSNFSRYDPRFNTWIHLANMIQKRTHFSLNTFNGLLFAVGGRNSDGCQASVECYVPSSNQWQMKAPMEVPRCCHASSVIDGKILVSGGYINNAYSRAVCSYDPSTDSWQDKNSLSSPRGWHCSVTVGDRAYVLGGSQLGGRGERVDVLPVECYNPHSGQWSYVAPLLTGVSTAGAATLNNKIYLLGGWNEIEKKYKKCIQVYNPDLNEWTEDDELPEATVGISCCVVTIPTRKTRESRASSVSSAPVSI", "length": 635 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6ZPT1-1", "protein_name": "Kelch-like protein 9", "gene_name": "Klhl9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKVSLGNGDMGVSAHLQPCKSGTTRFFTSNTHSSVVLQGFDQLRIEGLLCDVTLVPGDGEEIFPVHRAMMASASDYFKAMFTGGMKEKDLMCIKLHGVNKVGLKKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVSLDNCVEVGRIANTYNLIEVDKYVNNFILKNFPALLNTGEFLKLPFERLAFVLSSNSLKHCSELELFKAACRWLRLEDPRMDYAAKLMKNIRFPLMTPQDLINYVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSDRTAIRSDSTHLVTLGGVLRQQLVVSKELRMYDERAQEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGHLYAVGGRSAAGELATVECYNPRMNEWSYVAKMSEPHYGHAGTVYGGLMYISGGITHDTFQNELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDKLYVIGGNHFRGTSDYDDVLSCEYYSPTLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDLPESLGGIRACTLTVFPPEENPGSPSRESPLSAPSDHS", "length": 617 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q80TF4-1", "protein_name": "Kelch-like protein 13", "gene_name": "Klhl13", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLKWKTSSPAIWKFPVPVLKTSRSTPLSPAYISLVEEEDQHLKLCLGSEMGLSSHLQSCKAGSTRIFTSNSHSSVVLQGFDQLRLDGLLCDVTLMPGDTDDAYPVHRVMMASASDYFKAMFTGGMKEQELMCIKLHGVSRVGLRKIIDFIYTAKLSLNMDTLQDTLEAASFLQILPVLDFCKVFLISGVTLDNCVEVGRIANTYHLTEVDKYVNSFVLKNFAALLSTGEFLKLPFERLAFVLSSNSLKRCTELDLFKATCRWLRLEEPRMDVAAKLMKNIRFPLMTPQELINYVQTVDFMRTDNTCVNLLLEASNYQMMPFMQPVMQSDRTAIRSDTTRLVTLGGVLRQQLVVSKELRMYDEKTHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWIQVASLNEKRTFFHLSALKGFLYAVGGRNAAGELPTVECYNPRTNEWTYVAKMNEPHYGHAGTVYGGVMYISGGITHDTFQKELMCFDPDTDKWTQKAPMTTVRGLHCMCTVGDRLYVIGGNHFRGTSDYDDVLSCEYYSPILDQWTPIASMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKNEWHKVFDLPESLGGIRACTLTVYPPEEATPSPSRESPLSGP", "length": 654 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BGY4-1", "protein_name": "Kelch-like protein 26", "gene_name": "Klhl26", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAESGGSSGSSQSPERPSSLADRNGALKCTFSAAGHSTGLLQGLAALRAQGQLLDVVLTVNSEAFHAHKVVLAACSDYFRAMFTGGMREANQAVIQLQGVSARGLRHIIDFAYSAEVTLDLDCVQDVLGAAVFLQMLPVVELCEDFLKAAMSVETCLHIGQMATTFSLTSLRESVDAFTFRHFLQIAAEEDFLRLPLERLVFFLQSNRLQSCAEIDLFRAAVRWLQHDPARRARASLVLRHVRFPLMQPAELVDSVQTLDVMLDDALCRQYLLEAFSYHVLPCRQHDMQSPRTAVRSDVASLVAFGGTPYTDSDRAVSSKVFQLPEPGARHFRELTEMELGCSHAGVAVLDNFVYVAGGQHLQHRSGEGAVDACYRYDPQRNRWLRLRALRESRVQFQLTALGGLLYATGGRNRAGSLASVERYCPRRDSWDFACPLKRRTWGHAGAAAAGRLYISGGYGVSAEDKKALQCYDPAADRWEPRAPMREPRVLHAMLGAAGRIYALGGRMDHVDRCFDVLAVEYYVPDADQWTSVTPMRAGQSEAGCCLLERKIYIVGGYNWRLNNVTGIVQVYNTETDEWERDLHFPESFAGIACAAVLLPRSGHGR", "length": 606 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BWA5-1", "protein_name": "Kelch-like protein 31", "gene_name": "Klhl31", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPKKKTIKKNKAEINEMTIIVEDSPLSKLNALNGLLEGSNSLSCVSSELTDTSYGPNLLEGLSKMRQESFLCDLVIGTKTKSFDVHKSVMASCSEYFYNILKNDPSTKRVDLNDIAPLGLATVIAYAYTGKLTLSLYTIGSIISAAVYLQIHTLVKMCSDFLIREISVENCMYVVNIAETYSLKNAKATAQKFIRDNFIEFAESEQFMKLTFEQINELLVDDDLQLPSELVAFQIAMKWLEFDQKRVKHAADLLSNIRFGTISAQDLVNYVQTVPRMMQDADCHKLLVDAMNYHLLPYHQNTLQSRRTRIRGGCRVLITVGGRPGLTEKSLSRDILYRDPENGWSKLTEMPAKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLGSMNQKRTHFSLSVFNGLLYAVGGRNSEGSLASLECYVPSTNQWQPKAPLEVARCCHASAVADGRVIVTGGYIGSAYSRSVCAYDPALDAWQELPQLSTPRGWHCAVALGDRLYVMGGSQLGPRGERVDVLTVESFSPAARQWSFVAPLPVGVSTAGVSALHGRAYLLGGWNEGDKKYKKCIQCFNPELNEWTEDDELPEATVGVSCCTLAMPNSVSRESRASSVSSVPVSI", "length": 634 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N239-1", "protein_name": "Kelch-like protein 34", "gene_name": "KLHL34", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSYFLSYCKAHGGALLTGYQALRAEGFLCDVTLETEGSEFPAHRSLLACSSDYFRALFKSHTQESRARVIHLHVPSAAGLQRLLDFIYTAWLSLSMDTVEDTLEAASYLQVTEALGLCGRYLERQLAPENCCFAANVAARFGLAHTLDAAERCIVSHLQELLARGAGPAGLLELNPTSLRAVLGAPDVARVPEARLLGLALAWLRQEPTTERLAHCTELLERVRFGLVPADVLRRVYSGSGLVLPARVKGLIIQALNYHTTPSRQPLMQGEQTSIRSPQTRILLVGGRRAREVVIEEVAAPQRAARGQVAAPEPEEEEEELEEEEEEEEWELTQNVVAFDVYNHRWRSLTQLPTPLLGHSVCTAGNFLFVLGGESPSGSASSPLADDSRVVTAQVHRYDPRFHAWTEVPAMREARAHFWCGAVGERLLAVGGLGAGGEVLASVEMYDLRRDRWTAAGALPRALHGHAGAVGDRGVVYISGGKAGRGEGGASSLRDLYVLGPEEQVWSKKAPMGTARFGHHMAVLRGAVFAFLGRYEPFSEIERYDPGADQWTRLRPLPYDRFCYGLAVVEETALLLGGLKWRDSRQVPTRNVVGYDLDLDRWEDIGCALPWAWSGLRCAVLQLAEGGDDEREGEVGEALDLVLG", "length": 644 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N4N3-1", "protein_name": "Kelch-like protein 36", "gene_name": "KLHL36", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMEGSRQTRVSRPYKISESSKVYRWADHSSTVLQRLNEQRLRGLFCDVVLVADEQRVPAHRNLLAVCSDYFNSMFTIGMREAFQKEVELIGASYIGLKAVVDFLYGGELVLDGGNIDYVLETAHLLQIWTVVDFCCEYLEQEVSEDNYLYLQELASIYSLKRLDAFIDGFILNHFGTLSFTPDFLQNVSMQKLCVYLSSSEVQRECEHDLLQAALQWLTQQPEREAHARQVLENIHFPLIPKNDLLHRVKPAVCSLLPKEANCEGFIEEAVRYHNNLAAQPVMQTKRTALRTNQERLLFVGGEVSERCLELSDDTCYLDAKSEQWVKETPLPARRSHHCVAVLGGFIFIAGGSFSRDNGGDAASNLLYRYDPRCKQWIKVASMNQRRVDFYLASIEDMLVAIGGRNENGALSSVETYSPKTDSWSYVAGLPRFTYGHAGTIYKDFVYISGGHDYQIGPYRKNLLCYDHRTDVWEERRPMTTARGWHSMCSLGDSIYSIGGSDDNIESMERFDVLGVEAYSPQCNQWTRVAPLLHANSESGVAVWEGRIYILGGYSWENTAFSKTVQVYDREADKWSRGVDLPKAIAGGSACVCALEPRPEDKKKKGKGKRHQDRGQ", "length": 616 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96M94-1", "protein_name": "Kelch-like protein 15", "gene_name": "KLHL15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGDVEGFCSSIHDTSVSAGFRALYEEGLLLDVTLVIEDHQFQAHKALLATQSDYFRIMFTADMRERDQDKIHLKGLTATGFSHVLQFMYYGTIELSMNTVHEILQAAMYVQLIEVVKFCCSFLLAKICLENCAEIMRLLDDFGVNIEGVREKLDTFLLDNFVPLMSRPDFLSYLSFEKLMSYLDNDHLSRFPEIELYEAVQSWLRHDRRRWRHTDTIIQNIRFCLMTPTSVFEKVKTSEFYRYSRQLRYEVDQALNYFQNVHQQPLLDMKSSRIRSAKPQTTVFRGMIGHSMVNSKILLLKKPRVWWELEGPQVPLRPDCLAIVNNFVFLLGGEELGPDGEFHASSKVFRYDPRQNSWLQMADMSVPRSEFAVGVIGKFIYAVAGRTRDETFYSTERYDITNDKWEFVDPYPVNKYGHEGTVLNNKLFITGGITSSSTSKQVCVFDPSKEGTIEQRTRRTQVVTNCWENKSKMNYARCFHKMISYNGKLYVFGGVCVILRASFESQGCPSTEVYNPETDQWTILASMPIGRSGHGVTVLDKQIMVLGGLCYNGHYSDSILTFDPDENKWKEDEYPRMPCKLDGLQVCNLHFPDYVLDEVRRCN", "length": 604 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q96NJ5-1", "protein_name": "Kelch-like protein 32", "gene_name": "KLHL32", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPSERCLSIQEMLTGQRLCHSESHNDSVLAALNQQRSDGILCDITLIAEEQKFHAHKAVLAACSDYFRAMFSLCMVESGADEVNLHGVTSLGLKQALEFAYTGQILLEPGVIQDVLAAGSHLQLLELLNLCSHYLIQELNSFNYLDLYRLADLFNLTLLEKAVIDFLVKHLSELLKSRPEEVLTLPYCLLQEVLKSDRLTSLSEEQIWQLAVRWLEHNCHYQYMDELLQYIRFGLMDVDTLHTVALSHPLVQASETATALVNEALEYHQSIYAQPVWQTRRTKPRFQSDTLYIIGGKKREVCKVKELRYFNPVDQENALIAAIANWSELAPMPVGRSHHCVAVMGDFLFVAGGEVEHASGRTCAVRTACRYDPRSNSWAEIAPMKNCREHFVLGAMEEYLYAVGGRNELRQVLPTVERYCPKKNKWTFVQSFDRSLSCHAGYVADGLLWISGGVTNTAQYQNRLMVYEPNQNKWISRSPMLQRRVYHSMAAVQRKLYVLGGNDLDYNNDRILVRHIDSYNIDTDQWTRCNFNLLTGQNESGVAVHNGRIYLVGGYSIWTNEPLACIQVLDVSREGKEEVFYGPTLPFASNGIAACFLPAPYFTCPNLQTLQVPHHRIGTI", "length": 620 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9H511-1", "protein_name": "Kelch-like protein 31", "gene_name": "KLHL31", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPKKKIVKKNKGDINEMTIIVEDSPLNKLNALNGLLEGGNGLSCISSELTDASYGPNLLEGLSKMRQENFLCDLVIGTKTKSFDVHKSVMASCSEYFYNILKKDPSIQRVDLNDISPLGLATVIAYAYTGKLTLSLYTIGSIISAAVYLQIHTLVKMCSDFLIREMSVENCMYVVNIAETYSLKNAKAAAQKFIRDNFLEFAESDQFMKLTFEQINELLIDDDLQLPSEIVAFQIAMKWLEFDQKRVKYAADLLSNIRFGTISAQDLVNYVQSVPRMMQDADCHRLLVDAMNYHLLPYHQNTLQSRRTRIRGGCRVLVTVGGRPGLTEKSLSRDILYRDPENGWSKLTEMPAKSFNQCVAVMDGFLYVAGGEDQNDARNQAKHAVSNFCRYDPRFNTWIHLASMNQKRTHFSLSVFNGLVYAAGGRNAEGSLASLECYVPSTNQWQPKTPLEVARCCHASAVADGRVLVTGGYIANAYSRSVCAYDPASDSWQELPNLSTPRGWHCAVTLSDRVYVMGGSQLGPRGERVDVLTVECYSPATGQWSYAAPLQVGVSTAGVSALHGRAYLVGGWNEGEKKYKKCIQCFSPELNEWTEDDELPEATVGVSCCTLSMPNNVTRESRASSVSSVPVSI", "length": 634 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9P2J3-1", "protein_name": "Kelch-like protein 9", "gene_name": "KLHL9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVSLGNGEMGVSAHLQPCKAGTTRFFTSNTHSSVVLQGFDQLRIEGLLCDVTLVPGDGDEIFPVHRAMMASASDYFKAMFTGGMKEQDLMCIKLHGVNKVGLKKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVSLDNCVEVGRIANTYNLIEVDKYVNNFILKNFPALLSTGEFLKLPFERLAFVLSSNSLKHCTELELFKAACRWLRLEDPRMDYAAKLMKNIRFPLMTPQDLINYVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSDRTAIRSDSTHLVTLGGVLRQQLVVSKELRMYDERAQEWRSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGHLYAVGGRSAAGELATVECYNPRMNEWSYVAKMSEPHYGHAGTVYGGLMYISGGITHDTFQNELMCFDPDTDKWMQKAPMTTVRGLHCMCTVGDKLYVIGGNHFRGTSDYDDVLSCEYYSPTLDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPEKDEWHKVFDLPESLGGIRACTLTVFPPEENPGSPSRESPLSAPSDHS", "length": 617 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9P2N7-1", "protein_name": "Kelch-like protein 13", "gene_name": "KLHL13", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLKWKTSSPAIWKFPVPVLKTSRSTPLSPAYISLVEEEDQHMKLSLGGSEMGLSSHLQSSKAGPTRIFTSNTHSSVVLQGFDQLRLEGLLCDVTLMPGDTDDAFPVHRVMMASASDYFKAMFTGGMKEQDLMCIKLHGVSKVGLRKIIDFIYTAKLSLNMDNLQDTLEAASFLQILPVLDFCKVFLISGVTLDNCVEVGRIANTYNLTEVDKYVNSFVLKNFPALLSTGEFLKLPFERLAFVLSSNSLKHCTELELFKATCRWLRLEEPRMDFAAKLMKNIRFPLMTPQELINYVQTVDFMRTDNTCVNLLLEASNYQMMPYMQPVMQSDRTAIRSDTTHLVTLGGVLRQQLVVSKELRMYDEKAHEWKSLAPMDAPRYQHGIAVIGNFLYVVGGQSNYDTKGKTAVDTVFRFDPRYNKWMQVASLNEKRTFFHLSALKGYLYAVGGRNAAGELPTVECYNPRTNEWTYVAKMSEPHYGHAGTVYGGVMYISGGITHDTFQKELMCFDPDTDKWIQKAPMTTVRGLHCMCTVGERLYVIGGNHFRGTSDYDDVLSCEYYSPILDQWTPIAAMLRGQSDVGVAVFENKIYVVGGYSWNNRCMVEIVQKYDPDKDEWHKVFDLPESLGGIRACTLTVFPPEETTPSPSRESPLSAP", "length": 655 }, "evidence": [ { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VRA7-1", "protein_name": "Kelch-like protein diablo", "gene_name": "Dmel\\CG1812", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAATPAPAVTPAATATSAAAKIPVNPVSPEEETLLRGLNKLRNEEKLTDVTLIVEEHRFKAHRVVLAASSDYFCAMFADCAMIESRKDEINLYGIKARAMGSIIDYIYTSMLELNYDNIEEILAAATHVQVREVIDRCTIFLGAKIEMENCLAIAGMADIYGIMDLSERAYRYMCAHFEEFATTSDFKEMKVDQLRFILSSNYPIDVAEQDLVRLVCSFAIEQQLNESALGDLLRLIKWQHISYKSVDELRNMNCSLDKGKQLPLPTSYYNRIKQEHMGHLLNGVVSLKDQSLPQGPTNMRGMELCLLKIGGFEWNGLTNVIMCFSPKKMNWYELTAIPHIDQCNFGTAVLNNKLFIVGGAYDVFLKEYIHPFGFCYCPLRNTWMTIAPIQQDRCRFSLNAVGTQHLYAVGGILDDDNEEALRMISNVERYDIAKNVWTYMPSLQENRSQHAGVVVGDKLYISGGVHLANILASMWVFDTKTEVWQELASMPTPCCDHVLVAVDNRIYACGGWHESLTEWRVLVEHIYAYDIETNTWSVETKIPAPKFYTGVTAMGRTIFFVGGLDSTESIDRASAETMAYDLDTKEWWHEKDSWDSPNDVWESTCVAIYVPNCDA", "length": 616 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-081105-100", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081105-100#orthology", "database": "AGR" }, { "id": "FB:FBgn0031119", "url": "https://alliancegenome.org/gene/FB:FBgn0031119#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "E9QHV0", "url": "https://www.uniprot.org/uniprotkb/E9QHV0" } ], "pmid": "" }, { "name": "regulation of cytokinesis", "id": "GO:0032465", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0032465", "evidence": [ { "database": "UniProtKB", "id": "E9QHV0", "url": "https://www.uniprot.org/uniprotkb/E9QHV0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "E9QHV0", "url": "https://www.uniprot.org/uniprotkb/E9QHV0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "E9QHV0", "url": "https://www.uniprot.org/uniprotkb/E9QHV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 234, "end_pos": 236, "annotation": "n_glycosylation_sequon" }, { "start_pos": 479, "end_pos": 481, "annotation": "n_glycosylation_sequon" }, { "start_pos": 82, "end_pos": 84, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E9QHV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QHV0" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 104, "end_pos": 173, "start_aa": "Cys", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 65 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 }, { "start_pos": 479, "end_pos": 481 }, { "start_pos": 82, "end_pos": 84 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": 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"id": "PTHR44229", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44229", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44229:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44229:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E7F258", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E7F258", "database": "PRO", "categories": [ "Protein" ] }, { "id": "R-DRE-2142700", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-2142700", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9018676", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9018676", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9018896", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9018896", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001313470", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313470", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "11876", "url": "https://www.rhea-db.org/rhea/11876", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "16477", "url": "https://www.rhea-db.org/rhea/16477", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "23260", "url": "https://www.rhea-db.org/rhea/23260", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41263", "url": "https://www.rhea-db.org/rhea/41263", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41572", "url": "https://www.rhea-db.org/rhea/41572", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "41596", "url": "https://www.rhea-db.org/rhea/41596", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "48640", "url": "https://www.rhea-db.org/rhea/48640", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "48952", "url": "https://www.rhea-db.org/rhea/48952", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "49244", "url": "https://www.rhea-db.org/rhea/49244", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50124", "url": "https://www.rhea-db.org/rhea/50124", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "50128", "url": "https://www.rhea-db.org/rhea/50128", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53584", "url": "https://www.rhea-db.org/rhea/53584", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53588", "url": "https://www.rhea-db.org/rhea/53588", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M9QCH9", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QCH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QCH9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QCH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F258", "url": "https://www.uniprot.org/uniprotkb/E7F258", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F258-1", "url": "https://www.uniprot.org/uniprotkb/E7F258-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080728-2", "url": "https://zfin.org/ZDB-GENE-080728-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSLHGKTALVTGGAQGIGRAVVEELLQNGAKVALVDLNQSVGEECKSDLDDQFGEDNCIFIQCDVTDGEKLGDAFRNTVDRFGRLDIVINNAGINNEKNWEKTIEVNLTSVIKGTYLALEHMSKEYGKQGGAIINVSSMAAFLHSPHQPVYTATKYGVIGFSRAMADASEQGNYGVRINALCPAFVDTQLLQTVEHEETMGKFVKYKDDFKQRMDKYGVLKPSLIAEGMLRLITDESLNGAVMKITCSKGIHFHTYEPLSA", "length": 261, "header": "tr|E7F258-1|E7F258_DANRE Isoform 1 of 15-hydroxyprostaglandin dehydrogenase [NAD(+)] OS=Danio rerio OX=7955 GN=hpgd PE=3 SV=1 CANONICAL=E7F258-1" }, "isoforms": [ { "isoform_ac": "A0A8M9QCH9-1", "url": "https://www.uniprot.org/uniprotkb/E7F258/entry#A0A8M9QCH9-1", "sequence": { "sequence": "MSLHGKTALVTGGAQGIGRAVVEELLQNGAKVALVDLNQSVGEECKSDLDDQFGEDNCIFIQCDVTDGEKLGDAFRNTVDRFGRLDIVINNAGINNEKNWEKTIEVNLTSVIKGTYLALEHMSKEYGKQGGAIINVSSMAAFLHSPHQPVYTATKYGVIGFSRAMADASEQGNYGVRINALCPAFVDTQLLQTVEHEETMGHR", "length": 203, "header": "tr|A0A8M9QCH9-1|E7F258_DANRE Computationally mapped isoform of 15-hydroxyprostaglandin dehydrogenase [NAD(+)] OS=Danio rerio OX=7955 GN=hpgd PE=3 SV=1 CANONICAL=E7F258-1" }, "locus": {} }, { "isoform_ac": "E7F258-1", "url": "https://www.uniprot.org/uniprotkb/E7F258/entry#E7F258-1", "sequence": { "sequence": "MSLHGKTALVTGGAQGIGRAVVEELLQNGAKVALVDLNQSVGEECKSDLDDQFGEDNCIFIQCDVTDGEKLGDAFRNTVDRFGRLDIVINNAGINNEKNWEKTIEVNLTSVIKGTYLALEHMSKEYGKQGGAIINVSSMAAFLHSPHQPVYTATKYGVIGFSRAMADASEQGNYGVRINALCPAFVDTQLLQTVEHEETMGKFVKYKDDFKQRMDKYGVLKPSLIAEGMLRLITDESLNGAVMKITCSKGIHFHTYEPLSA", "length": 261, "header": "tr|E7F258-1|E7F258_DANRE Isoform 1 of 15-hydroxyprostaglandin dehydrogenase [NAD(+)] OS=Danio rerio OX=7955 GN=hpgd PE=3 SV=1 CANONICAL=E7F258-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7F258", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "An embryonic atrazine exposure results in reproductive dysfunction in adult zebrafish and morphological alterations in their offspring.", "journal": "Sci. Rep.", "date": "2016", "authors": "Wirbisky Sara E, Weber Gregory J, Sep\u00falveda Maria S, Lin Tsang-Long, Jannasch Amber S, Freeman Jennifer L", "evidence": [ { "database": "UniProtKB", "id": "E7F258", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ], "reference": [ { "type": "PubMed", "id": "26891955", "url": "https://glygen.org/publication/PubMed/26891955" } ] }, { "title": "Individual knock out of glycine receptor alpha subunits identifies a specific requirement of glra1 for motor function in zebrafish.", "journal": "PLoS ONE", "date": "2019", "authors": "Samarut Eric, Chalopin Domitille, Rich\u00e9 Rapha\u00eblle, Allard Marc, Liao Meijiang, Drapeau Pierre", "evidence": [ { "database": "UniProtKB", "id": "E7F258", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ], "reference": [ { "type": "PubMed", "id": "31048868", "url": "https://glygen.org/publication/PubMed/31048868" } ] }, { "title": "PGE2 inhibits spermatogonia differentiation in zebrafish: interaction with Fsh and an androgen.", "journal": "J. Endocrinol.", "date": "2020", "authors": "Crespo Diego, Lemos Moline Severino, Zhang Yu Ting, Safian Diego, Norberg Birgitta, Bogerd Jan, Schulz R\u00fcdiger W", "evidence": [ { "database": "UniProtKB", "id": "E7F258", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ], "reference": [ { "type": "PubMed", "id": "31600720", "url": "https://glygen.org/publication/PubMed/31600720" } ] }, { "title": "Disruption of Epidermal Growth Factor Receptor but Not EGF Blocks Follicle Activation in Zebrafish Ovary.", "journal": "Front. Cell Dev. Biol.", "date": "2021", "authors": "Song Yanlong, Chen Weiting, Zhu Bo, Ge Wei", "evidence": [ { "database": "UniProtKB", "id": "E7F258", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ], "reference": [ { "type": "PubMed", "id": "35111746", "url": "https://glygen.org/publication/PubMed/35111746" } ] }, { "title": "Exercise intervention mitigates zebrafish age-related sarcopenia via alleviating mitochondrial dysfunction.", "journal": "FEBS J.", "date": "2023", "authors": "Sun Chen-Chen, Yang Dong, Chen Zhang-Lin, Xiao Jiang-Ling, Xiao Qin, Li Cheng-Li, Zhou Zuo-Qiong, Peng Xi-Yang, Tang Chang Fa, Zheng Lan", "evidence": [ { "database": "UniProtKB", "id": "E7F258", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ], "reference": [ { "type": "PubMed", "id": "36164851", "url": "https://glygen.org/publication/PubMed/36164851" } ] } ], "pathway": [ { "id": "dre:565975", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565975", "resource": "KEGG Pathway" }, { "id": "R-DRE-2142700", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-2142700", "resource": "Reactome", "description": "Biosynthesis of Lipoxins (LX)" }, { "id": "R-DRE-9018676", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9018676", "resource": "Reactome", "description": "Biosynthesis of D-series resolvins" }, { "id": "R-DRE-9018896", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9018896", "resource": "Reactome", "description": "Biosynthesis of E-series 18(S)-resolvins" } ], "orthologs": [ { "uniprot_canonical_ac": "E1C688-1", "protein_name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "gene_name": "HPGD", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHVNGKVALVTGGAQGIGRAFVQALLGKGAKVALLDRNPEAGQQSKAALDEQFEAQRTVFIQCDVTDTEQLKGAFKKVIEHFGRLDIVVNNAGVNNEKDWESTIQINLTSVIRGTYLGLEYMRKGNGGDGGVIINISSLAGLMPAAFQPVYCATKHGVIGFTRSIALAANMENYGVRLNTICPGFVNTPILQSIDKEENMGQYYSYKDEIKNMMQFYGVMDPSIIAEGLITIIEDDTLNGEVMKITASQGIHFQEYSQTPYTSKR", "length": 265 }, "evidence": [ { "id": "E7F258", "url": "https://omabrowser.org/oma/group/E7F258/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O08699-1", "protein_name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "gene_name": "Hpgd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MHVNGKVALVTGAAQGIGKAFTEALLLHGAKVALVDWNLETGVKCKAALDEQFEPQKTLFIQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINISSIAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVKTPILESIEKEENMGQYIEYTDQIKAMMKFYGILDPSAIANGLINLIEDDALNGAIMKITASKGIHFQDYDLFPSFSKAP", "length": 266 }, "evidence": [ { "id": "HGNC:5154", "url": "https://alliancegenome.org/gene/HGNC:5154#orthology", "database": "AGR" }, { "id": "MGI:108085", "url": "https://alliancegenome.org/gene/MGI:108085#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P15428-1", "protein_name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "gene_name": "HPGD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLFIQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDALNGAIMKITTSKGIHFQDYDTTPFQAKTQ", "length": 266 }, "evidence": [ { "id": "HGNC:5154", "url": "https://alliancegenome.org/gene/HGNC:5154#orthology", "database": "AGR" }, { "id": "MGI:108085", "url": "https://alliancegenome.org/gene/MGI:108085#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080728-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080728-2#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54398-1", "protein_name": "Fat body protein 2", "gene_name": "Fbp2", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFDWTGKNVVYVGSFSGIGWQMMMQLMQKDIKMMGIMHRMENVKMMKKLQAINPSVKVVFMQMNLMEKMSIEQAMKKMGQMMGHIDVMINGEGVLLDKDVETTMGMNLTGMIQSTMMAMPYMDKTQMGMGGMVVNMSSVYGLEPAPAFSVYAAAMHGILGFTRSMGDKMIYQKTGVMFMAMCPGLTNSEMIMNLRDNVTWHHSESMVEAIESAKRQMPEEAAMQMIHAMEMMKNGSMWIVSMGQLKEVTPTMHWQM", "length": 256 }, "evidence": [ { "id": "HGNC:5154", "url": "https://alliancegenome.org/gene/HGNC:5154#orthology", "database": "AGR" }, { "id": "MGI:108085", "url": "https://alliancegenome.org/gene/MGI:108085#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P91615-1", "protein_name": "Alcohol dehydrogenase-related 31 kDa protein", "gene_name": "Adhr", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFDLTGKHVCYVADCGGIALETSKVLMTKNIAKLAILQSTENPQAIAQLQSIKPSTQIFFWTYDVTMAREDMKKYFDEVMVQMDYIDVLINGATLCDENNIDATINTNLTGMMNTVATVLPYMDRKMGGTGGLIVNVTSVIGLDPSPVFCAYSASKFGVIGFTRSLADPLYYSQNGVAVMAVCCGPTRVFVDRELKAFLEYGQSFADRLRRAPCQSTSVCGQNIVNAIERSENGQIWIADKGGLELVKLHWYWHMADQFVHYMQSNDEEDQD", "length": 272 }, "evidence": [ { "id": "HGNC:5154", "url": "https://alliancegenome.org/gene/HGNC:5154#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8VCC1-1", "protein_name": "15-hydroxyprostaglandin dehydrogenase [NAD(+)]", "gene_name": "Hpgd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHVNGKVALVTGAAQGIGKAFAEALLLHGAKVALVDWNLEAGVKCKAALDEQFEPQKTLFVQCDVADQKQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEQTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIIGFTRSAAMAANLMKSGVRLNVICPGFVDTPILESIEKEENMGQYIEYKDQIKAMMKFYGVLHPSTIANGLINLIEDDALNGAIMKITASKGIHFQDYDISPLLVKAPLTS", "length": 269 }, "evidence": [ { "id": "HGNC:5154", "url": "https://alliancegenome.org/gene/HGNC:5154#orthology", "database": "AGR" }, { "id": "MGI:108085", "url": "https://alliancegenome.org/gene/MGI:108085#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080728-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080728-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9I7R3-1", "protein_name": "Alcohol dehydrogenase", "gene_name": "Dmel\\CG18814", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLEGKNVVYLGGFGGIGKKCVQELLKKQIKGLAIFDLIVDDDLLAEWKKQHPDTEIFYQKMDITQKSDIDAAYKATAEKLGHFDVVVNGSGLLDDRRIELTIQINLVGVINSTLTALEYMDKSKGGRGGLIVNISSVAGLQPTPLMAIYSTSKTGVTTFTRAMASPIHYAHSGVGFITICPGYTNTGILKDIDKKTTFPFYETRMRTVFSKVKGQTAEVCARNIVNAIETAKNGAVLMLELGEIHELDIPNLWNPQLDDCVFVCLS", "length": 267 }, "evidence": [ { "id": "HGNC:5154", "url": "https://alliancegenome.org/gene/HGNC:5154#orthology", "database": "AGR" }, { "id": "MGI:108085", "url": "https://alliancegenome.org/gene/MGI:108085#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VV42-1", "protein_name": "Fat body protein 2", "gene_name": "Pdh", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKPQGIPPTTTRISQTKMSFRGKNAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKKGVEATYEEIAKTFGNIDIVVNVAGIFNDKDVQRTLLVNLGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKIIFPETSDETYRILDRLNKQSAADVSRCILNVLEKDKNGAVYVIEGKRVYPLEIKPQWTGKEQAL", "length": 278 }, "evidence": [ { "id": "HGNC:5154", "url": "https://alliancegenome.org/gene/HGNC:5154#orthology", "database": "AGR" }, { "id": "MGI:108085", "url": "https://alliancegenome.org/gene/MGI:108085#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VV47-1", "protein_name": "Fat body protein 2", "gene_name": "Dmel\\CG4842", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDLAGKNVVYLGGFGGIGQKCVQELLQRPIKALAIFDLNANEQLLAKWKSQHPDTDVFYHKLDITQKSDIDAAYKATAERFGHFDVVVNGSGLMNDRLVELTIQINLLGVINSTLTALEYMDKAKGGKGGLIVNISSVAGLQPTAIMAIYSAAKTGVTTFTRAMANPYFYAHSGVGFLTICPGFTDTGLLEDIGNKTTFTYDTPMLAMFNRVKRQKAEDCARNLVSAIETSKNGTVLMLEMGETTEVDMPVMWKPQLDN", "length": 259 }, "evidence": [ { "id": "HGNC:5154", "url": "https://alliancegenome.org/gene/HGNC:5154#orthology", "database": "AGR" }, { "id": "MGI:108085", "url": "https://alliancegenome.org/gene/MGI:108085#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "prostaglandin metabolic process", "id": "GO:0006693", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006693", "evidence": [ { "database": "UniProtKB", "id": "E7F258", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "15-hydroxyprostaglandin dehydrogenase (NAD+) activity", "id": "GO:0016404", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016404", "evidence": [ { "database": "UniProtKB", "id": "E7F258", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ], "pmid": "" }, { "name": "15-hydroxyicosatetraenoate dehydrogenase activity", "id": "GO:0047034", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047034", "evidence": [ { "database": "UniProtKB", "id": "E7F258", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ], "pmid": "" }, { "name": "oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor", "id": "GO:0016616", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016616", "evidence": [ { "database": "UniProtKB", "id": "E7F258", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7F258", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 107, "end_pos": 109, "annotation": "n_glycosylation_sequon" }, { "start_pos": 135, "end_pos": 137, "annotation": "n_glycosylation_sequon" }, { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "11876", "name": "", "equation": "prostaglandin E2 + NAD(+) = 15-oxoprostaglandin E2 + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "11876", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/11876" } ] }, { "id": "16477", "name": "", "equation": "prostaglandin E1 + NAD(+) = 15-oxoprostaglandin E1 + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "16477", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16477" } ] }, { "id": "23260", "name": "", "equation": "(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NAD(+) = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "23260", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/23260" } ] }, { "id": "41263", "name": "", "equation": "prostaglandin A1 + NAD(+) = 15-oxo-prostaglandin A1 + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "41263", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41263" } ] }, { "id": "41572", "name": "", "equation": "lipoxin A4 + NAD(+) = 15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z,13E)-eicosatetraenoate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "41572", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41572" } ] }, { "id": "41596", "name": "", "equation": "15-oxo-(5S,6R)-dihydroxy-(7E,9E,11Z)-eicosatrienoate + NADH + H(+) = (5S,6R,15S)-trihydroxy-(7E,9E,11Z)-eicosatrienoate + NAD(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "41596", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/41596" } ] }, { "id": "48640", "name": "", "equation": "(11R)-hydroxy-(5Z,8Z,12E,14Z)-eicosatetraenoate + NAD(+) = 11-oxo-(5Z,8Z,12E,14Z)-eicosatetraenoate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "48640", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48640" } ] }, { "id": "48952", "name": "", "equation": "14-hydroxy-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + NAD(+) = 14-oxo-(4Z,7Z,10Z,12E,16Z,19Z)-docosahexaenoate + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "48952", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/48952" } ] }, { "id": "49244", "name": "", "equation": "resolvin E1 + NAD(+) = 18-oxo-resolvin E1 + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "49244", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/49244" } ] }, { "id": "50124", "name": "", "equation": "resolvin D1 + NAD(+) = 8-oxoresolvin D1 + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "50124", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50124" } ] }, { "id": "50128", "name": "", "equation": "resolvin D1 + NAD(+) = 17-oxoresolvin D1 + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "50128", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/50128" } ] }, { "id": "53584", "name": "", "equation": "resolvin D2 + NAD(+) = 7-oxoresolvin D2 + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "53584", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53584" } ] }, { "id": "53588", "name": "", "equation": "resolvin D2 + NAD(+) = 16-oxoresolvin D2 + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E7F258-1", "A0AC58IBD1-1" ], "evidence": [ { "id": "53588", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53588" } ] }, { "id": "R-DRE-2161779", "name": "LXA4 is oxidised to 15k-LXA4 by HPGD", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-2161759" ], "output_participant_list": [ "R-ALL-2142761" ], "enzyme_list": [ "E7F258-1" ], "evidence": [ { "id": "R-DRE-2161779", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-2161779" } ] }, { "id": "R-DRE-9023968", "name": "HPGD dimer oxidises 18(S)-RvE1 to 18-oxo-RvE1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-9022660" ], "output_participant_list": [ "R-ALL-9023963" ], "enzyme_list": [ "E7F258-1" ], "evidence": [ { "id": "R-DRE-9023968", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9023968" } ] }, { "id": "R-DRE-9024766", "name": "HPGD dimer oxidises RvD1 to 17(S)-oxo-RvD1 and 8-oxo-17(S)-RvD1", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-9024764" ], "output_participant_list": [], "enzyme_list": [ "E7F258-1" ], "evidence": [ { "id": "R-DRE-9024766", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9024766" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-2142761", "participant_name": "15k-LXA4 [cytosol]", "crossref": [ { "id": "ZINC000087528765", "database": "ZINC", "url": "" }, { "id": "78311", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-2161759", "participant_name": "LXA4 [cytosol]", "crossref": [ { "id": "67026", "database": "ChEBI", "url": "" }, { "id": "ZINC000004097074", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9022660", "participant_name": "18(S)-RvE1 [cytosol]", "crossref": [ { "id": "136057", "database": "ChEBI", "url": "" } ] }, { "participant_id": "R-ALL-9023963", "participant_name": "18-oxo-RvE1 [cytosol]", "crossref": [ { "id": "91001", "database": "ChEBI", "url": "" }, { "id": "ZINC000059202944", "database": "ZINC", "url": "" } ] }, { "participant_id": "R-ALL-9024764", "participant_name": "RvD1 [cytosol]", "crossref": [ { "id": "132079", "database": "ChEBI", "url": "" }, { "id": "ZINC000012496201", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "A0AC58IBD1", "gene_name": "zgc:56585", "activity": [ { "ec_number": "1.1.1.141", "activity": "prostaglandin E2 + NAD(+) = 15-oxoprostaglandin E2 + NADH + H(+).", "evidence": [ { "id": "A0AC58IBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58IBD1" } ] }, { "ec_number": "1.1.1.232", "activity": "(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADP(+) = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADPH + H(+).", "evidence": [ { "id": "A0AC58IBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58IBD1" } ] }, { "ec_number": "1.1.1.232", "activity": "", "evidence": [ { "id": "A0AC58IBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58IBD1" } ] }, { "ec_number": "1.1.1.141", "activity": "", "evidence": [ { "id": "A0AC58IBD1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0AC58IBD1" } ] } ] }, { "uniprot_ac": "E7F258", "gene_name": "hpgd", "activity": [ { "ec_number": "1.1.1.141", "activity": "prostaglandin E2 + NAD(+) = 15-oxoprostaglandin E2 + NADH + H(+).", "evidence": [ { "id": "E7F258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ] }, { "ec_number": "1.1.1.232", "activity": "(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADP(+) = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADPH + H(+).", "evidence": [ { "id": "E7F258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ] }, { "ec_number": "1.1.1.141", "activity": "", "evidence": [ { "id": "E7F258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ] }, { "ec_number": "1.1.1.232", "activity": "", "evidence": [ { "id": "E7F258", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F258" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.1.1.141", "ec_name": "prostaglandin E2 + NAD(+) = 15-oxoprostaglandin E2 + NADH + H(+).", "evidence": [ { "id": "1.1.1.141", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.141" }, { "id": "1.1.1.141", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.1.1.141" } ] }, { "ec_number": "1.1.1.232", "ec_name": "(15S)-hydroxy-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADP(+) = 15-oxo-(5Z,8Z,11Z,13E)-eicosatetraenoate + NADPH + H(+).", "evidence": [ { "id": "1.1.1.232", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.1.1.232" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 107, "end_pos": 109 }, { "start_pos": 135, "end_pos": 137 }, { "start_pos": 38, "end_pos": 40 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 6 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F392-1", "uniprot_ac": "E7F392", "uniprot_id": "E7F392_DANRE", "mass": { "chemical_mass": 67594.0, "monoisotopic_mass": 67594.0 }, "refseq": { "ac": "XP_697274", "name": "cytoskeleton-associated protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697274" }, "gene_names": [ { "name": "si:ch211-266i6.3", "type": "recommended", "evidence": [ { "id": "E7F392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F392" } ] }, { "name": "si:ch211-266i6.3", "type": "synonym", "evidence": [ { "id": "XP_697274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697274" } ] } ], "protein_names": [ { "name": "Cytoskeleton-associated protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F392/entry#names_and_taxonomy" } ] }, { "name": "cytoskeleton-associated protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_697274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697274" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_697274.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_697274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697274" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F392", "url": "https://www.uniprot.org/uniprotkb/E7F392" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-266i6.3", "url": "https://www.uniprot.org/uniprotkb/E7F392", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-5420", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-5420", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000086112", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000086112", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "568826", "url": "https://www.ncbi.nlm.nih.gov/gene/568826", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026165", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026165", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029197", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029197", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:568826", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568826", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCLITRA", "url": "https://omabrowser.org/oma/group/KCLITRA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F392", "url": "https://www.orthodb.org/?gene=E7F392", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16076", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16076", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16076:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16076:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15297", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15297", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_697274", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_697274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9QCL0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QCL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QCL0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QCL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F392", "url": "https://www.uniprot.org/uniprotkb/E7F392", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F392-1", "url": "https://www.uniprot.org/uniprotkb/E7F392-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-5420", "url": "https://zfin.org/ZDB-GENE-030131-5420", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNIMESVVRKRNKENTKPVSGLKKQVISSTASKQRVLCKTAPLQSKNDLKEDNSGKKGKDVRAQNKSNDADPAKRYTLSQAFRTQQTIRQRKLVEEVQKPPSTVSAVQKSKPGTYKGRVIQSKIDCFRKPSGDVKTTEKKVISKPDETKAKPEVSKIRSKSVTSLQTSIKPRVNSALSSRSKSVSDVPRNVTEKPVHKSVSLKQIPQKVPSSISQTGAHRACVLPRPAPLATGRSATNKAFTMKKKVPVQVPKPKPPLTDQNVSRPVTSTVSQYKVQMETAEERRAKLAEWLASKGKSLKRPPISDNSAVLSRKPAPQPKPGPKATTCAQSKPVMQKTEPVKPAPALKTSNQTDKVPGTKPVNTSESSNIMNTTLDLLDNSDMDLPVDPEIRMESLVMNLCDKLEAMETPSSCEDAMNADECDAPADKRMEMQVEEHTTDRVFEILEEEELGDEEDITDDIKKADIKNEDDLEPQEKKLFDSEDDDGEEMRCTTPETEGASIVKYNVKTTPYLQSVKKRIECEEAPGSGSRRKSTIKDLKFLTPVRRSTRIQRKSSRLPGMLNDHDTCVSSLAELVQMEDADANAYIYRKNPALLEDLPNHPGDLAKVCS", "length": 610, "header": "tr|E7F392-1|E7F392_DANRE Isoform 1 of Cytoskeleton-associated protein 2 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-266i6.3 PE=3 SV=1 CANONICAL=E7F392-1" }, "isoforms": [ { "isoform_ac": "A0A8M9QCL0-1", "url": "https://www.uniprot.org/uniprotkb/E7F392/entry#A0A8M9QCL0-1", "sequence": { "sequence": "MNIMESVRNKENTKPVSGLKKQVISSTASKQRVLCKTAPLQSKNDLKEDNSGKKGKDVRAQNKSNDADPAKRYTLSQAFRTQQTIRQRKLVEEVQKPPSTVSAVQKSKPGTYKGRVIQSKIDCFRKPSGDVKTTEKKVISKPDETKAKPEVSKIRSKSVTSLQTSIKPRVNSALSSRSKSVSDVPRNVTEKPVHKSVSLKQIPQKVPSSISQTGAHRACVLPRPAPLATGRSATNKAFTMKKKVPVQVPKPKPPLTDQNVSRPVTSTVSQYKVQMETAEERRAKLAEWLASKGKSLKRPPISDNSAVLSRKPAPQPKPGPKATTCAQSKPVMQKTEPVKPAPALKTSNQTDKVPGTKPVNTSESSNIMNTTLDLLDNSDMDLPVDPEIRMESLVMNLCDKLEAMETPSSCEDAMNADECDAPADKRMEMQVEEHTTDRVFEILEEEELGDEEDITDDIKKADIKNEDDLEPQEKKLFDSEDDDGEEMRCTTPETEGASIVKYNVKTTPYLQSVKKRIECEEAPGSGSRRKSTIKDLKFLTPVRRSTRIQRKSSRLPGMLNDHDTCVSSLAELVQMEDADANAYIYRKNPALLEDLPNHPGDLAKVCS", "length": 607, "header": "tr|A0A8M9QCL0-1|E7F392_DANRE Computationally mapped isoform of Cytoskeleton-associated protein 2 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-266i6.3 PE=3 SV=1 CANONICAL=E7F392-1" }, "locus": {} }, { "isoform_ac": "E7F392-1", "url": "https://www.uniprot.org/uniprotkb/E7F392/entry#E7F392-1", "sequence": { "sequence": "MNIMESVVRKRNKENTKPVSGLKKQVISSTASKQRVLCKTAPLQSKNDLKEDNSGKKGKDVRAQNKSNDADPAKRYTLSQAFRTQQTIRQRKLVEEVQKPPSTVSAVQKSKPGTYKGRVIQSKIDCFRKPSGDVKTTEKKVISKPDETKAKPEVSKIRSKSVTSLQTSIKPRVNSALSSRSKSVSDVPRNVTEKPVHKSVSLKQIPQKVPSSISQTGAHRACVLPRPAPLATGRSATNKAFTMKKKVPVQVPKPKPPLTDQNVSRPVTSTVSQYKVQMETAEERRAKLAEWLASKGKSLKRPPISDNSAVLSRKPAPQPKPGPKATTCAQSKPVMQKTEPVKPAPALKTSNQTDKVPGTKPVNTSESSNIMNTTLDLLDNSDMDLPVDPEIRMESLVMNLCDKLEAMETPSSCEDAMNADECDAPADKRMEMQVEEHTTDRVFEILEEEELGDEEDITDDIKKADIKNEDDLEPQEKKLFDSEDDDGEEMRCTTPETEGASIVKYNVKTTPYLQSVKKRIECEEAPGSGSRRKSTIKDLKFLTPVRRSTRIQRKSSRLPGMLNDHDTCVSSLAELVQMEDADANAYIYRKNPALLEDLPNHPGDLAKVCS", "length": 610, "header": "tr|E7F392-1|E7F392_DANRE Isoform 1 of Cytoskeleton-associated protein 2 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-266i6.3 PE=3 SV=1 CANONICAL=E7F392-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:568826", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568826", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E7F392", "url": "https://www.uniprot.org/uniprotkb/E7F392" } ], "pmid": "" }, { "name": "microtubule cytoskeleton", "id": "GO:0015630", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015630", "evidence": [ { "database": "UniProtKB", "id": "E7F392", "url": "https://www.uniprot.org/uniprotkb/E7F392" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of microtubule depolymerization", "id": "GO:0007026", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007026", "evidence": [ { "database": "UniProtKB", "id": "E7F392", "url": "https://www.uniprot.org/uniprotkb/E7F392" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 190, "end_pos": 192, "annotation": "n_glycosylation_sequon" }, { "start_pos": 262, "end_pos": 264, "annotation": "n_glycosylation_sequon" }, { "start_pos": 351, "end_pos": 353, "annotation": "n_glycosylation_sequon" }, { "start_pos": 363, "end_pos": 365, "annotation": "n_glycosylation_sequon" }, { "start_pos": 372, "end_pos": 374, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F392", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F392" }, { "id": "PF15297", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15297" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cytoskeleton-associated protein 2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 259, "end_pos": 305, "start_aa": "Thr", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 190, "end_pos": 192 }, { "start_pos": 262, "end_pos": 264 }, { "start_pos": 351, "end_pos": 353 }, { "start_pos": 363, "end_pos": 365 }, { "start_pos": 372, "end_pos": 374 }, { "start_pos": 65, "end_pos": 67 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F2K3-1", "uniprot_ac": "E7F2K3", "uniprot_id": "E7F2K3_DANRE", "mass": { "chemical_mass": 18940.0, "monoisotopic_mass": 18940.0 }, "refseq": { "ac": "NP_001188274", "name": "type-1 angiotensin II receptor-associated protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188274" }, "gene_names": [ { "name": "agtrap", "type": "recommended", "evidence": [ { "id": "E7F2K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2K3" } ] }, { "name": "agtrap", "type": "synonym", "evidence": [ { "id": "NP_001188274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188274" } ] }, { "name": "im:6894391", "type": "synonym", "evidence": [ { "id": "NP_001188274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188274" }, { "id": "E7F2K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2K3" } ] } ], "protein_names": [ { "name": "Type-1 angiotensin II receptor-associated protein", "type": "synonym", "evidence": [ { "id": "E7F2K3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F2K3/entry#names_and_taxonomy" } ] }, { "name": "type-1 angiotensin II receptor-associated protein", "type": "synonym", "evidence": [ { "id": "NP_001188274", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188274" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH437438.1, EB769248.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EH437438.1. On or before Jan 14, 2011 this sequence version replaced XP_002663776.1, XP_002663781.1, XP_002663782.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001188274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188274" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F2K3", "url": "https://www.uniprot.org/uniprotkb/E7F2K3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "agtrap", "url": "https://www.uniprot.org/uniprotkb/E7F2K3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050309-11", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050309-11", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077082", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077082", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "793937", "url": "https://www.ncbi.nlm.nih.gov/gene/793937", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:793937", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793937", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IMNGWAV", "url": "https://omabrowser.org/oma/group/IMNGWAV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F2K3", "url": "https://www.orthodb.org/?gene=E7F2K3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16521", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16521", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16521:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16521:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06396", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06396", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001188274", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188274", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9QHT1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QHT1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QHT1-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QHT1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F2K3", "url": "https://www.uniprot.org/uniprotkb/E7F2K3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F2K3-1", "url": "https://www.uniprot.org/uniprotkb/E7F2K3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050309-11", "url": "https://zfin.org/ZDB-GENE-050309-11", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEIPAINLKAILLVHWILTVWACLLSWLPASYVLGNFSVLAVGVWAIAQRDSIDAVLLFLIGLAVTILTDIVHFGIYYAAAELLYERSTRDLFRFSGGMAILSLLLKPVSCFFVYQMYRERGGEYNVNFGFPSISRNRDAYQSIDHNDQSGSSANPFGQAEDGKSGTRSY", "length": 170, "header": "tr|E7F2K3-1|E7F2K3_DANRE Isoform 1 of Type-1 angiotensin II receptor-associated protein OS=Danio rerio OX=7955 GN=agtrap PE=4 SV=2 CANONICAL=E7F2K3-1" }, "isoforms": [ { "isoform_ac": "A0A8M9QHT1-1", "url": "https://www.uniprot.org/uniprotkb/E7F2K3/entry#A0A8M9QHT1-1", "sequence": { "sequence": "MEIPAINLKAILLVHWILTVWACLLSWLPASYVLGNFSVLAVGVWAIAQRDSIDAVLLFLIGLAVTILTDIVHFGIYYAAAELLYERSTRDLFRFSGGMAILSLLLKPVSCFFVYQMYRERGGEYNVNFDLETSMDSRCTTDSADSTLLGRRY", "length": 153, "header": "tr|A0A8M9QHT1-1|E7F2K3_DANRE Computationally mapped isoform of Type-1 angiotensin II receptor-associated protein OS=Danio rerio OX=7955 GN=agtrap PE=4 SV=1 CANONICAL=E7F2K3-1" }, "locus": {} }, { "isoform_ac": "E7F2K3-1", "url": "https://www.uniprot.org/uniprotkb/E7F2K3/entry#E7F2K3-1", "sequence": { "sequence": "MEIPAINLKAILLVHWILTVWACLLSWLPASYVLGNFSVLAVGVWAIAQRDSIDAVLLFLIGLAVTILTDIVHFGIYYAAAELLYERSTRDLFRFSGGMAILSLLLKPVSCFFVYQMYRERGGEYNVNFGFPSISRNRDAYQSIDHNDQSGSSANPFGQAEDGKSGTRSY", "length": 170, "header": "tr|E7F2K3-1|E7F2K3_DANRE Isoform 1 of Type-1 angiotensin II receptor-associated protein OS=Danio rerio OX=7955 GN=agtrap PE=4 SV=2 CANONICAL=E7F2K3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "E7F2K3", "url": "https://www.uniprot.org/uniprotkb/E7F2K3" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "The Lysosomal Transcription Factor TFEB Represses Myelination Downstream of the Rag-Ragulator Complex.", "journal": "Dev. 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"Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_009301876", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009301876", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A2R8PXC7", "url": "https://www.uniprot.org/uniprotkb/A0A2R8PXC7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2R8PXC7-1", "url": "https://www.uniprot.org/uniprotkb/A0A2R8PXC7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QI58", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QI58", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QI58-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QI58-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F4G2", "url": "https://www.uniprot.org/uniprotkb/E7F4G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F4G2-1", "url": "https://www.uniprot.org/uniprotkb/E7F4G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030911-10", "url": "https://zfin.org/ZDB-GENE-030911-10", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MARLADYFTVVGYDQEKAGSGEGCGKIIQRFPKKDWDGTAFPQGVEMFCQPGGWRLSRERKPPTFFTVVLTDIDSERHFCSCLTFFEAEVNLQGSKTLEADGEEEEEEEENGLIQPAEVFAPKSLILVSRLDYPEIFRGCLGLIYTVYIDSLNFPLEGLVANLFTCFVPLAGGSQKLFSLGAGDRQLIQTPLNDSLPVSSKSIALLFQQLGIQNVLSLFCAVLTEHKVLFHSSSYQRLGEACRALETLMFPLKYSYPYIPVLPSRLLEVLSSPTPFIIGVHSMFQSEIQELLDVIIADLDGGTIKIPECIHLSQLPEPLLHNTQKALFMVLHPDLEGADNAFPPPRSAPSNLKLLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHSEPVIHFHKAAFLGQRGLIENDFLTKVLDGMAFAGFVSERGPPYRACDLFDELVALDVDCFKDEDENLVKLQKRLRELSEQLYKNENPNPHMAFQKVPRPTEGSHLRVHVVPFPMLEEERVEELIQEGLAKQHSAPVSTRPEKKCVVPAGPPVVSIMGKASSVFNSARRLEVVRTCIGFIFDNKTLETEKTLPAALRALKGKAARQCLTEELSHHVQQNRAILDHQQFDHIVRMMNCALQDCSSSEEYTVAAALLPLTTAFYRKLAAGVDQFAYTCIQEHPIWTNQQFWEATFYSEVQNQIRALYLTAPEDKPLITAKIKEPSRLSTAAGQSERTAMDLAAEQLRAWPGLSKEKQHELVKSEESTVFSQAIHYASLMVYLLVPLDTSKNKLLRSNPAADWESGSNSILTNSIAGSVAESFDTESGFEDSETSDVANSVGRFISRFIDKVCTESGVTQDHIKSLHSMIPGIVAMQMETLEVVHRESRRLPPIQKPKILRPALLPGEELVSEGLRVVLDPDGREEATGGLLGGPHILPAEGALFLTTYRIVFKGTPHDPLVGEQAVIRSFPVSTLTKEKKITIQNQLQQNMQEGLQLRSASFQLIKVAFDEEVSSEMVEIFRKHVQRIRYPSSIFSTFAFAAGQTAPQLILPKQKERNTGFRTLSKTIVKGAIKAGKITMGRQSTLKKNEKGSRMTWHEDDDISISDDGEPPSSNTLKASEKSTMEQLVERACFRDYQRLGLGTISANSTRLKSGEQFRVTAVNRLYSLCRSYPGLLVIPHTVQDSSLQKVSRCYRHNRLPVVCWKHPRTKAVLLRSGGFHSKSVVGLFKSQNPSSAAPTSSDTSSSLEQEKYLQAILSSIPIYFKPNGSNTLTNRSLIGLSPASERRASRIPKMAPVHLDISFTNSFTRGVLGYRDKLFTHSNQKASAKGRIHNQGVWASLRSSSRFIQHPAVGDVGARLAGKDLAPPTGIENLQAQLLKHQAALYIFGEKSHFRGLKLDPALNCELVPVEFADTRQVKASFKKLLRACAPSAMSSDTEDSFLKALEESEWMLQIHKLLQLAVVAVELLDSGSSVLVSLEEGWDITTQVVSLTQVLSDPFYRTLEGFQVLLEKEWLSFGHKFSQRGNLNPNSQGSGFTPIFLQFLDCVHQVHNQYPLEFEFNQYYLKFLAYHYVSNRFKNFLLDSDYERLEHGTLFEDKGEKQSKRGICIWECINRMHRKGPLFFNYLYSPSETEPVLKPLISIPNLTTWEFYTGETLSTGPSYDWCMLTVRSQSMEESDTIATTKRRIVWPCYSSVSRAQPDAISKLLADIEKLEGEQGQHSEPWHTTLEKAIDGIQEDLKQEGNLRKQSLSISGLVPTSNLQAYQRRSMLHLPDGGLGEDNSPAAVNGVHRRAATLYNQFTPKNEDNRSFEGILYKRGALLKAWKARWFVLDTTKHQLRYYETDEDTSCRGFIDLADVESVLIAAPTIGAPKHISEKAFFDLKTNKRVYNFCAADAPSAQLWIDKIQSCISDA", "length": 1898, "header": "tr|E7F4G2-1|E7F4G2_DANRE Isoform 1 of Myotubularin-related protein 13 isoform X1 OS=Danio rerio OX=7955 GN=sbf2 PE=1 SV=1 CANONICAL=E7F4G2-1" }, "isoforms": [ { "isoform_ac": "A0A2R8PXC7-1", "url": "https://www.uniprot.org/uniprotkb/E7F4G2/entry#A0A2R8PXC7-1", "sequence": { "sequence": "MARLADYFTVVGYDQEKAGSGEGCGKIIQRFPKKDWDGTAFPQGVEMFCQPGGWRLSRERKPPTFFTVVLTDIDSERHFCSCLTFFEAEVNLQGSKTLEADGEEEEEEEENGLIQPAEVFAPKSLILVSRLDYPEIFRGCLGLIYTVYIDSLNFPLEGLVANLFTCFVPLAGGSQKLFSLGAGDRQLIQTPLNDSLPVSSKSIALLFQQLGIQNVLSLFCAVLTEHKVLFHSSSYQRLGEACRALETLMFPLKYSYPYIPVLPSRLLEVLSSPTPFIIGVHSMFQSEIQELLDVIIADLDGGTIKIPECIHLSQLPEPLLHNTQKALFMVLHPDLEGADNAFPPPRSAPSNLKLLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHSEPVIHFHKAAFLGQRGLIENDFLTKVLDGMAFAGFVSERGPPYRACDLFDELVALDVDCFKDEDENLVKLQKRLRELSEQLYKNENPNPHMAFQKVPRPTEGSHLRVHVVPFPMLEEERVEELIQEGLAKQHSAPVSTRPEKKCVVPAGPPVVSIMGKASSVFNSARRLEVVRTCIGFIFDNKTLETEKTLPAALRALKGKAARQCLTEELSHHVQQNRAILDHQQFDHIVRMMNCALQDCSSSEEYTVAAALLPLTTAFYRKLAAGVDQFAYTCIQEHPIWTNQQFWEATFYSEVQNQIRALYLTAPEDKPLITAKIKEPSRLSTAAGQSERTAMDLAAEQLRAWPGLSKEKQHELVKSEESTVFSQAIHYASLMVYLLVPLDTSKNKLLRSNPAADWESGSNSILTNSIAGSVAESFDTESGFEDSETSDVANSVGRFISRFIDKVCTESGVTQDHIKSLHSMIPGIVAMQMETLEVVHRESRRLPPIQKPKILRPALLPGEELVSEGLRVVLDPDGREEATGGLLGGPHILPAEGALFLTTYRIVFKGTPHDPLVGEQAVIRSFPVSTLTKEKKITIQNQLQQNMQEGLQLRSASFQLIKVAFDEEVSSEMVEIFRKHVQRIRYPSSIFSTFAFAAGQTAPQLILPKQKERNTGFRTLSKTIVKGAIKAGKITMGRQSTLKKNEKGSRMTWHEDDDISISDDGEPPSSNTLKASEKSTMEQLVERACFRDYQRLGLGTISANSTRLKSGEQFRVTAVNRLYSLCRSYPGLLVIPHTVQDSSLQKVSRCYRHNRLPVVCWKHPRTKAVLLRSGGFHSKSVVGLFKSQNPSSAAPTSSDTSSSLEQEKYLQAILSSIPIYFKPNGSNTLTNRSLIGLSPASERRASRIPKMAPVHLDISFTNSFTRGGVWASLRSSSRFIQHPAVGDVGARLAGKDLAPPTGIENLQAQLLKHQAALYIFGEKSHFRGLKLDPALNCELVPVEFADTRQVKASFKKLLRACAPSAMSSDTEDSFLKALEESEWMLQIHKLLQLAVVAVELLDSGSSVLVSLEEGWDITTQVVSLTQVLSDPFYRTLEGFQVLLEKEWLSFGHKFSQRGNLNPNSQGSGFTPIFLQFLDCVHQVHNQYPLEFEFNQYYLKFLAYHYVSNRFKNFLLDSDYERLEHGTLFEDKGEKQSKRGICIWECINRMHRKGPLFFNYLYSPSETEPVLKPLISIPNLTTWEFYTGETLSTGPSYDWCMLTVRSQSMEESDTIATTKRRIVWPCYSSVSRAQPDAISKLLADIEKLEGEQGQHSEPWHTTLEKAIDGIQEDLKQEGNLRKQSLSISGLVPTSNLQAYQRRSMLHLPDGGLGEDNSPAAVNGVHRRAATLYNQFTPKNEDNRSFEGILYKRGALLKAWKARWFVLDTTKHQLRYYETDEDTSCRGFIDLADVESVLIAAPTIGAPKHISEKAFFDLKTNKRVYNFCAADAPSAQLWIDKIQSCISDA", "length": 1873, "header": "tr|A0A2R8PXC7-1|E7F4G2_DANRE Computationally mapped isoform of Myotubularin-related protein 13 isoform X1 OS=Danio rerio OX=7955 GN=sbf2 PE=1 SV=1 CANONICAL=E7F4G2-1" }, "locus": {} }, { "isoform_ac": "A0A8M9QI58-1", "url": "https://www.uniprot.org/uniprotkb/E7F4G2/entry#A0A8M9QI58-1", "sequence": { "sequence": "MARLADYFTVVGYDQEKAGSGEGCGKIIQRFPKKDWDGTAFPQGVEMFCQPGGWRLSRERKPPTFFTVVLTDIDSERHFCSCLTFFEAEVNLQGSKTLEADGEEEEEEEENGLIQPAEVFAPKSLILVSRLDYPEIFRGCLGLIYTVYIDSLNFPLEGLVANLFTCFVPLAGGSQKLFSLGAGDRQLIQTPLNDSLPVSSKSIALLFQQLGIQNVLSLFCAVLTEHKVLFHSSSYQRLGEACRALETLMFPLKYSYPYIPVLPSRLLEVLSSPTPFIIGVHSMFQSEIQELLDVIIADLDGGTIKIPECIHLSQLPEPLLHNTQKALFMVLHPDLEGADNAFPPPRSAPSNLKLLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHSEPVIHFHKAAFLGQRGLIENDFLTKVLDGMAFAGFVSERGPPYRACDLFDELVALDVDCFKDEDENLVKLQKRLRELSEQLYKNENPNPHMAFQKVPRPTEGSHLRVHVVPFPMLEEERVEELIQEGLAKQHSAPVSTRPEKKCVVPAGPPVVSIMGKASSVFNSARRLEVVRTCIGFIFDNKTLETEKTLPAALRALKGKAARQCLTEELSHHVQQNRAILDHQQFDHIVRMMNCALQDCSSSEEYTVAAALLPLTTAFYRKLAAGVDQFAYTCIQEHPIWTNQQFWEATFYSEVQNQIRALYLTAPEDKPLITAKIKEPSRLSTAAGQSERTAMDLAAEQLRAWPGLSKEKQHELVKSEESTVFSQAIHYASLMVYLLVPLDTSKNKLLRSNPAADWESGSNSILTNSIAGSVAESFDTESGFEDSETSDVANSVGRFISRFIDKVCTESGVTQDHIKSLHSMIPGIVAMQMETLEVVHRESRRLPPIQKPKILRPALLPGEELVSEGLRVVLDPDGREEATGGLLGGPHILPAEGALFLTTYRIVFKGTPHDPLVGEQAVIRSFPVSTLTKEKKITIQNQLQQNMQEGLQLRSASFQLIKVAFDEEVSSEMVEIFRKHVQRIRYPSSIFSTFAFAAGQTAPQLILPKQKERNTGFRTLSKTIVKGAIKAGKITMGRQSTLKKNEKGSRMTWHEDDDISISDDGEPPSSNTLKASEKSTMEQLVERACFRDYQRLGLGTISANSTRLKSGEQFRVTAVNRLYSLCRSYPGLLVIPHTVQDSSLQKVSRCYRHNRLPVVCWKHPRTKAVLLRSGGFHSKSVVGLFKSQNPSSAAPTSSDTSSSLEQEKYLQAILSSIPIYFKPNGSNTLTNRSLIGLSPGVWASLRSSSRFIQHPAVGDVGARLAGKDLAPPTGIENLQAQLLKHQAALYIFGEKSHFRGLKLDPALNCELVPVEFADTRQVKASFKKLLRACAPSAMSSDTEDSFLKALEESEWMLQIHKLLQLAVVAVELLDSGSSVLVSLEEGWDITTQVVSLTQVLSDPFYRTLEGFQVLLEKEWLSFGHKFSQRGNLNPNSQGSGFTPIFLQFLDCVHQVHNQYPLEFEFNQYYLKFLAYHYVSNRFKNFLLDSDYERLEHGTLFEDKGEKQSKRGICIWECINRMHRKGPLFFNYLYSPSETEPVLKPLISIPNLTTWEFYTGETLSTGPSYDWCMLTVRSQSMEESDTIATTKRRIVWPCYSSVSRAQPDAISKLLADIEKLEGEQGQHSEPWHTTLEKAIDGIQEDLKQEGNLRKQSLSISGLVPTSNLQAYQRRSMLHLPDGGLGEDNSPAAVNGVHRRAATLYNQFTPKNEDNRSFEGILYKRGALLKAWKARWFVLDTTKHQLRYYETDEDTSCRGFIDLADVESVLIAAPTIGAPKHISEKAFFDLKTNKRVYNFCAADAPSAQLWIDKIQSCISDA", "length": 1845, "header": "tr|A0A8M9QI58-1|E7F4G2_DANRE Computationally mapped isoform of Myotubularin-related protein 13 isoform X1 OS=Danio rerio OX=7955 GN=sbf2 PE=1 SV=1 CANONICAL=E7F4G2-1" }, "locus": {} }, { "isoform_ac": "E7F4G2-1", "url": "https://www.uniprot.org/uniprotkb/E7F4G2/entry#E7F4G2-1", "sequence": { "sequence": "MARLADYFTVVGYDQEKAGSGEGCGKIIQRFPKKDWDGTAFPQGVEMFCQPGGWRLSRERKPPTFFTVVLTDIDSERHFCSCLTFFEAEVNLQGSKTLEADGEEEEEEEENGLIQPAEVFAPKSLILVSRLDYPEIFRGCLGLIYTVYIDSLNFPLEGLVANLFTCFVPLAGGSQKLFSLGAGDRQLIQTPLNDSLPVSSKSIALLFQQLGIQNVLSLFCAVLTEHKVLFHSSSYQRLGEACRALETLMFPLKYSYPYIPVLPSRLLEVLSSPTPFIIGVHSMFQSEIQELLDVIIADLDGGTIKIPECIHLSQLPEPLLHNTQKALFMVLHPDLEGADNAFPPPRSAPSNLKLLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHSEPVIHFHKAAFLGQRGLIENDFLTKVLDGMAFAGFVSERGPPYRACDLFDELVALDVDCFKDEDENLVKLQKRLRELSEQLYKNENPNPHMAFQKVPRPTEGSHLRVHVVPFPMLEEERVEELIQEGLAKQHSAPVSTRPEKKCVVPAGPPVVSIMGKASSVFNSARRLEVVRTCIGFIFDNKTLETEKTLPAALRALKGKAARQCLTEELSHHVQQNRAILDHQQFDHIVRMMNCALQDCSSSEEYTVAAALLPLTTAFYRKLAAGVDQFAYTCIQEHPIWTNQQFWEATFYSEVQNQIRALYLTAPEDKPLITAKIKEPSRLSTAAGQSERTAMDLAAEQLRAWPGLSKEKQHELVKSEESTVFSQAIHYASLMVYLLVPLDTSKNKLLRSNPAADWESGSNSILTNSIAGSVAESFDTESGFEDSETSDVANSVGRFISRFIDKVCTESGVTQDHIKSLHSMIPGIVAMQMETLEVVHRESRRLPPIQKPKILRPALLPGEELVSEGLRVVLDPDGREEATGGLLGGPHILPAEGALFLTTYRIVFKGTPHDPLVGEQAVIRSFPVSTLTKEKKITIQNQLQQNMQEGLQLRSASFQLIKVAFDEEVSSEMVEIFRKHVQRIRYPSSIFSTFAFAAGQTAPQLILPKQKERNTGFRTLSKTIVKGAIKAGKITMGRQSTLKKNEKGSRMTWHEDDDISISDDGEPPSSNTLKASEKSTMEQLVERACFRDYQRLGLGTISANSTRLKSGEQFRVTAVNRLYSLCRSYPGLLVIPHTVQDSSLQKVSRCYRHNRLPVVCWKHPRTKAVLLRSGGFHSKSVVGLFKSQNPSSAAPTSSDTSSSLEQEKYLQAILSSIPIYFKPNGSNTLTNRSLIGLSPASERRASRIPKMAPVHLDISFTNSFTRGVLGYRDKLFTHSNQKASAKGRIHNQGVWASLRSSSRFIQHPAVGDVGARLAGKDLAPPTGIENLQAQLLKHQAALYIFGEKSHFRGLKLDPALNCELVPVEFADTRQVKASFKKLLRACAPSAMSSDTEDSFLKALEESEWMLQIHKLLQLAVVAVELLDSGSSVLVSLEEGWDITTQVVSLTQVLSDPFYRTLEGFQVLLEKEWLSFGHKFSQRGNLNPNSQGSGFTPIFLQFLDCVHQVHNQYPLEFEFNQYYLKFLAYHYVSNRFKNFLLDSDYERLEHGTLFEDKGEKQSKRGICIWECINRMHRKGPLFFNYLYSPSETEPVLKPLISIPNLTTWEFYTGETLSTGPSYDWCMLTVRSQSMEESDTIATTKRRIVWPCYSSVSRAQPDAISKLLADIEKLEGEQGQHSEPWHTTLEKAIDGIQEDLKQEGNLRKQSLSISGLVPTSNLQAYQRRSMLHLPDGGLGEDNSPAAVNGVHRRAATLYNQFTPKNEDNRSFEGILYKRGALLKAWKARWFVLDTTKHQLRYYETDEDTSCRGFIDLADVESVLIAAPTIGAPKHISEKAFFDLKTNKRVYNFCAADAPSAQLWIDKIQSCISDA", "length": 1898, "header": "tr|E7F4G2-1|E7F4G2_DANRE Isoform 1 of Myotubularin-related protein 13 isoform X1 OS=Danio rerio OX=7955 GN=sbf2 PE=1 SV=1 CANONICAL=E7F4G2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 485, "start_aa": "Thr", "end_pos": 485, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr485", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:378456", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:378456", "resource": "KEGG Pathway" }, { "id": "R-DRE-8876198", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8876198", "resource": "Reactome", "description": "RAB GEFs exchange GTP for GDP on RABs" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K1T3-1", "protein_name": "SET binding factor 2", "gene_name": "Sbf2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARLADYFIVVGYDHEKPGPGEGLGKIIQRFPQQDWDDTPFPQGIELFCQPGGWHLSRERKQPTFFVVVLTDIDSDRHYCSCLTFYEAEINLQGTKKEEIEGEEVSALIQPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLSVSLESLIANLCACLVPAAGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLNLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSIFKTDVHELLDVIIADLDGGTIKIPECIHLSSLPEPLLHQTQAALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKTAFLGQRGLVENDFLTKVLNGMAFAGFVSERGPPYRACDLFDELVAFEVERIKVEENNPLKMIKHIRELAEQLFKNENPNPHMAFQKVPRPTEGSHLRVHILPFPKINEARVQELIQENLAKNQNATPATRTEKKCIVPAGPPVVSIMDKVITVFNSAQRLEVVRNCISFIFENKTLETEKTLPAALRALKGKAARQCLTDELGLHVQQNRAILDHQQFDYIIRMMNCTLQDCSSLEEYNIAAALLPLTSAFYRRLAPGVSQFAYTCVQDHPIWTNQQFWETTFYSAVQEQVRSLYLSAKEDNHTPHQKQKELPDGQYQERTAMDLAAEQLRLWPTLSKATQQELVQHEESTVFSQAIHFANLMVNLLVPLDTSKNKLLRASAPGDWESGSNSIVTNSIAGSVAESFDTESGFEDSENNDVANSVVRFIARFIDKVCTESGVTQDHIRSLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPALLPGEEIVCEGLRVLLDPDGREEATGGLLGGPQLLPAEGALFLTTYRILFRGTPHDQLVGEQTVVRSFPIASITKEKKITMQNQLQQNMQEGLQITSASFQLIKVAFDEEVSPEVVDIFKKQLMKFRYPQSIFSTFAFAAGQTTPQIILPKQKEKNTSFRTFSKTIVKGAKKAGKMTIGRQYLLKKRTGTIVEERANRPGWNEEDDISVSDDCELPTSTTLKASEKSTMEQLVEKACFRDYQRLGLGTISGSSSRSKPEYFRVTASNRLYSLCRSYPGLLVIPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAVSTSSLESSSSIEQEKYLQALLTAVIVHQKLRGNSTLTVRPTLALSPGVWASLRSSTRLISSPTSLIDVGARLAGKDHSASFSNSTYLQNQLSKRQAALYIFGEKSQLRSSKVEFAFNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALEDSEWFPQLHRIMQLAVVVSEVLENGSSVWVCLEEGWDITTQVTSLVQLLSDPFYRTIEGFRMLVEKEWLSFGHKFSQRSSLALNSQGSGFAPIFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGDKHAKKGVCIWECIDKMHKRSPVFFNYLYSPVEIEALKPNVNVSSLKKWDYYTEETLSAGPSYDWMMLTPKHFPYEESDVAGGAGPQSQRKTVWPCYDDVTCSQPDALTRLFSEIEKLEHKLNQTPEKWHQLWEKITMDLKEEPRTDHSLRHSSRSPGIASTNVPSYQKRPALHALHRSPTEDQSTTTAPSNGVEHRAATLYSQYTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVEMVVPAGPSMGAPKYTSDKAFFDLKTSKRVYNFCAQDGQSAQQWMDRIQSCISDA", "length": 1847 }, "evidence": [ { "id": "HGNC:2135", "url": "https://alliancegenome.org/gene/HGNC:2135#orthology", "database": "AGR" }, { "id": "MGI:1921831", "url": "https://alliancegenome.org/gene/MGI:1921831#orthology", "database": "AGR" }, { "id": "E7F4G2", "url": "https://omabrowser.org/oma/group/E7F4G2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8V0ZNP8-1", "protein_name": "SET binding factor 2", "gene_name": "SBF2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MARLADYFIVVGYDHEKTAGPAEGLGKIIQRFPQKDWEDTPFPQGIELFCQPGGWQLSKERKQPTFFVVVLTDIDSERHYCSCLTFYEAEINLQGTKETEGEEESGLIAPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSLNVSLEALIANLCSCLVPASGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFRNDIHELLDVIIADLDGGTIKIPECIHLSQLPEPLLHQTQMALSLVLHPDLETADYAFPPPRTALSHTKMLDKEVRAIFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKAAFLGQRGLIENDFLTKVLNGMAFAGFVSERGPPFRACDLFDELVAFEVERIKADEGNPPKMIKHVRELAEQLFKNENPNPHIAFQKVPRPTEGSHLRVHILPFPRINECRVQELLQEGLARSQGAPSATRGDKKCVVPAGPPVVSIMEKGSTVFNSAQRLEVVRNCISFIFENKFLETEKTLPAALRALKGKAARHCLTQELGLHVKQNRAILDHQQFDYIVRMMNCALQDCSSSEEYSVAAALLPLTTAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYSNVQNQVRSLYLTAKEDNHAVHPRQKEKNSVGPDHDKTAMDLAAEQLRLWPTLNKQTQQELVQNEESTVFSQAIHFANLMVYLLVPLDTSKNKLLRASATGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENNDVANAVVRFITRFIDKVCTESGVTQDHIKGLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPTLLPGEEFVCEGLRVLLDPDGREEATGGLLGGPHILPAEGALFLTTYRIIFKGTPHDQLVGEQTVIRSFPIASVTKEKKITIQNQLQQSMQEGLQITSATFQLIKVAFDEEVSPEVVEIFKKQLMKFRYPQSIFSAFAFAAGQTAPQIILPKQKEKNTSFRTFSKSIVKGAKRAGKMTIGRQYLLKKKTGTIMEERGNRPGWNEDDDVSVSDDSDLHTSGTLKASEKSTMEQLVERACFRDYQRLGLGTISSNTSRSKMEYLRITALNRMYSLCRSYPGLLVVPQSVQDSSLQRVARCYRHNRLPVVCWRNTKNSSLLLRSGGFHGKGVVGLFKSQNTHTAAPASLESSSSIEQEKYLQALLNVISVHCKMNGSNTLTVRPTIALSPGTDRRASRMSTVFKQVVPGHLDVNLSNSFARGVVGYRDKCFTHSNSKSATKGRVHQGVWASLRSSNRFINAQTPFIDVGARLAGKDNTTSYSSTFLQSQLLRRQAALYIFGEKSQLRGFKLDFALNCEFVPVEFSDIRQTKASFKKLLRACVPSTIPTDSEATFLKALGESEWFPQLHRIMQLGVIISELLENGSSVMVCLEDGWDITAQVVSLVQLLSDPFYRTLEGFRMLVEKEWLSFGHKFSQRSNLTLNCQGSGFAPIFLQFLDCVHQIHNQYPTEFEFNQYYLKFLAFHHISNRFKTFLLDSDYERLEHGTLFEDKGDKHNKKGVCIWECIEKMHKRSPIFFNYLYAPTEIEALKPNVSMSSLKKWDYYVEEILATGPSYDWNMVAAKCSALEEADQTDGSVSQKKRKIVWPCYDDVKKIQPDAISSLLNEIERLESKLNQNPERWQLLWERVKMNLKDDTRQDNLQRHPSGSSGMMSANLHSYQKRSLLEMPDNGLGEEQSASISPSNGVDRRATTLYNHFTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVETVIPASPTIGAPKHASEKAFFDLKTNKRVYNFCAQDAQSAQQWMDRIQSCISDA", "length": 1901 }, "evidence": [ { "id": "E7F4G2", "url": "https://omabrowser.org/oma/group/E7F4G2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9PXF8-1", "protein_name": "Myotubularin-related protein 13", "gene_name": "Sbf2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARLADYFIVVGYDHEKPAGPGEGLGKIIQRFPQQDWDDTPFPQGIELFCQPGGWHLSRERKQPTFFVVVLTDIDSDRHYCSCLTFYEAEINLQGTKKEEIEGEEVSGLIQPAEVFAPKSLVLVSRLDYPEIFRACLGLIYTVYVDSMSVSLESLIANLCACLVPAAGGSQKLFSLGAGDRQLIQTPLHDSLPVTGTSVALLFQQLGIQNVLNLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSIFKTDVHELLDVIIADLDGGTIKIPECIHLSSLPEPLLHQTQSALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKTAFLGQRGLVENDFLTKVLNGMAFAGFVSERGPPYRACDLFDELVAFEVERIKVEEKNPLKMIKHIRELAEQLFKNENPNPHMAFQKVPRPTEGSHLRVHILPFPKINEARVQELIQENLAKNQNAPPATRIEKKCVVPAGPPVVSIMEKVITVFNSAQRLEVVRNCISFIFENKTLETEKTLPAALRALKGKAARQCLTDELGLHVQQNRAILDHQQFDYIIRMMNCTLQDCSSLEEYNIAAALLPLTSAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYNAVQEQVRSLYLSAKDDNHIPHLKQKLPDGQHQEKTAMDLAAEQLRLWPTLSKSTQQELVQHEESTVFSQAIHFANLMVNLLVPLDTSKNKLLRASAPGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENSDVANSVVRFIARFIDKVCTESGVTQDHIRSLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPALLPGEEIVCEGLRVLLDPDGREEATGGLLGGPQLLPAEGALFLTTYRILFRGTPHDQLVGEQTVVRSFPIASITKEKKITMQNQLQQSVQEGLQITSASFQLIKVAFDEEVSPEVVDIFKKQLMKFRYPQSIFSTFAFAAGQTTPQIILPKQKEKNTSFRTFSKTIVKGAKKAGKMTIGRQYLLKKRTGTIVEERVNRPGWNEEDDISVSDDSELPTSTTLKASEKSTMEQLVEKACFRDYQRLGLGTISGNSSRSKPEYFRVTASNRLYSLCRSYPGLLVIPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAVSTSSLESSSSIEQEKYLQALLTAVIVHQKLRGSSTLTVRPALALSPVHGYRDKSFTQSNPKSSAKEPVHNQGVWASLRSSTRLISSPTSFIDVGARLAGKDHSASFSNSTYLQNQLLKRQAALYIFGEKSQLRSSKVEFAFNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRIMQLAVVVSEVLENGSSVWVCLEEGWDITTQVTSLAQLLSDPFYRTIAGFRTLVEKEWLSFGHKFSQRSSLALNSQGGGFAPIFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGDKHAKKGVCIWECIDKMHTRSPIFFNYLYSPVEVEALKPNVNVSSLKKWDYYTEETLSAGPSYDWMMLTPKHFPYEESDVAGGAGPQSQRKTVWPCYDDVTCSQPDALTRLFSEIEKLEHKLNQTPERWHQLWEKVTTDLKEEPRTAHSLRHSAGSPGIASTNVPSYQKRPALHPLHRGLGEDQSTTTAPSNGVEHRAATLYSQYTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVEMVIPAGPSMGAPKYTSDKAFFDLKTSKRVYNFCAQDGQSAQQWMDRIQSCISDA", "length": 1872 }, "evidence": [ { "id": "HGNC:2135", "url": "https://alliancegenome.org/gene/HGNC:2135#orthology", "database": "AGR" }, { "id": "MGI:1921831", "url": "https://alliancegenome.org/gene/MGI:1921831#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030911-10", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030911-10#orthology", "database": "AGR" }, { "id": "E7F4G2", "url": "https://omabrowser.org/oma/group/E7F4G2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86WG5-1", "protein_name": "Myotubularin-related protein 13", "gene_name": "SBF2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MARLADYFIVVGYDHEKPGSGEGLGKIIQRFPQKDWDDTPFPQGIELFCQPGGWQLSRERKQPTFFVVVLTDIDSDRHYCSCLTFYEAEINLQGTKKEEIEGEAKVSGLIQPAEVFAPKSLVLVSRLYYPEIFRACLGLIYTVYVDSLNVSLESLIANLCACLVPAAGGSQKLFSLGAGDRQLIQTPLHDSLPITGTSVALLFQQLGIQNVLSLFCAVLTENKVLFHSASFQRLSDACRALESLMFPLKYSYPYIPILPAQLLEVLSSPTPFIIGVHSVFKTDVHELLDVIIADLDGGTIKIPECIHLSSLPEPLLHQTQSALSLILHPDLEVADHAFPPPRTALSHSKMLDKEVRAVFLRLFAQLFQGYRSCLQLIRIHAEPVIHFHKTAFLGQRGLVENDFLTKVLSGMAFAGFVSERGPPYRSCDLFDELVAFEVERIKVEENNPVKMIKHVRELAEQLFKNENPNPHMAFQKVPRPTEGSHLRVHILPFPEINEARVQELIQENVAKNQNAPPATRIEKKCVVPAGPPVVSIMDKVTTVFNSAQRLEVVRNCISFIFENKILETEKTLPAALRALKGKAARQCLTDELGLHVQQNRAILDHQQFDYIIRMMNCTLQDCSSLEEYNIAAALLPLTSAFYRKLAPGVSQFAYTCVQDHPIWTNQQFWETTFYNAVQEQVRSLYLSAKEDNHAPHLKQKDKLPDDHYQEKTAMDLAAEQLRLWPTLSKSTQQELVQHEESTVFSQAIHFANLMVNLLVPLDTSKNKLLRTSAPGDWESGSNSIVTNSIAGSVAESYDTESGFEDSENTDIANSVVRFITRFIDKVCTESGVTQDHIKSLHCMIPGIVAMHIETLEAVHRESRRLPPIQKPKILRPALLPGEEIVCEGLRVLLDPDGREEATGGLLGGPQLLPAEGALFLTTYRILFRGTPHDQLVGEQTVVRSFPIASITKEKKITMQNQLQQNMQEGLQITSASFQLIKVAFDEEVSPEVVEIFKKQLMKFRYPQSIFSTFAFAAGQTTPQIILPKQKEKNTSFRTFSKTIVKGAKRAGKMTIGRQYLLKKKTGTIVEERVNRPGWNEDDDVSVSDESELPTSTTLKASEKSTMEQLVEKACFRDYQRLGLGTISGSSSRSRPEYFRITASNRMYSLCRSYPGLLVVPQAVQDSSLPRVARCYRHNRLPVVCWKNSRSGTLLLRSGGFHGKGVVGLFKSQNSPQAAPTSSLESSSSIEQEKYLQALLNAVSVHQKLRGNSTLTVRPAFALSPGVWASLRSSTRLISSPTSFIDVGARLAGKDHSASFSNSSYLQNQLLKRQAALYIFGEKSQLRNFKVEFALNCEFVPVEFHEIRQVKASFKKLMRACIPSTIPTDSEVTFLKALGDSEWFPQLHRIMQLAVVVSEVLENGSSVLVCLEEGWDITAQVTSLVQLLSDPFYRTLEGFQMLVEKEWLSFGHKFSQRSSLTLNCQGSGFAPVFLQFLDCVHQVHNQYPTEFEFNLYYLKFLAFHYVSNRFKTFLLDSDYERLEHGTLFDDKGEKHAKKGVCIWECIDRMHKRSPIFFNYLYSPLEIEALKPNVNVSSLKKWDYYIEETLSTGPSYDWMMLTPKHFPSEDSDLAGEAGPRSQRRTVWPCYDDVSCTQPDALTSLFSEIEKLEHKLNQAPEKWQQLWERVTVDLKEEPRTDRSQRHLSRSPGIVSTNLPSYQKRSLLHLPDSSMGEEQNSSISPSNGVERRAATLYSQYTSKNDENRSFEGTLYKRGALLKGWKPRWFVLDVTKHQLRYYDSGEDTSCKGHIDLAEVEMVIPAGPSMGAPKHTSDKAFFDLKTSKRVYNFCAQDGQSAQQWMDKIQSCISDA", "length": 1849 }, "evidence": [ { "id": "HGNC:2135", "url": "https://alliancegenome.org/gene/HGNC:2135#orthology", "database": "AGR" }, { "id": "MGI:1921831", "url": "https://alliancegenome.org/gene/MGI:1921831#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030911-10", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030911-10#orthology", "database": "AGR" }, { "id": "E7F4G2", "url": "https://omabrowser.org/oma/group/E7F4G2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VGH9-1", "protein_name": "SET domain binding factor, isoform A", "gene_name": "Sbf", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRLADYFVIVGYDSDKEKTASNVGGQPTCGKIVQRFPEKDWPDTPFIEGIEWFCQPLGWSLSYEKQEPKFFVSVLTDIDANKHYCACLSFHETVAITQTRSVDDEDETIGSSRLLGATPSSMDGITTTSTPASITHHSVMYAPKCLVLISRLDCAETFKNCLGTIYTVYIENLAYGLETLIGNILGCIQVPPAGGPQVRFSIGAGDKQSLQPPQSSSLPTTGSGVHFLFKQLGIKNVLILLCSVMTENKILFLSKCYWHLTDSCRALVALMYPFRYTHVYIPILPAPLTEVLSTPTPFIMGIHSSLQTEITDLLDVIVVDLDGGLVTIPESLTPPVPILPSPLWEQTQDLLSMILFPNLAQADLAFPTLERPSAIAKTDAQIDKELRAIFMRLFAQLLQGYRSCLTIIRIHPKPVITFHKAGFLGARDLIESEFLFRVLDSMFFTTFVNERGPPWRSSDAWDELYSSMNELLKSEAQNRNLVGRTQRFKGYFNFTFPSYFQILTHIQELGRVLYENEGTLAHISYAQKVLRPPEGAFQRIHQPAFPRISSEKVELIIQEGIRKNGVPQRFHVTRNQHRIIPMGPRLPEALDVRPNVQNSARRLEVLRICVSYIFENRITDARKLLPAVMRTLMHRDARLILCREFFGYVHGNKAVLDHQQFELVVRFMNKALQKSSGIDEYTVAAALLPMSTIFCRKLSTGVVQFAYTEIQDHAIWKNLQFWESTFFQDVQGQIKALYLLHRRQNEHQKEANCVLDEVPLEEPTALEITAEQLRKSPNIEEEKKAELAKSEESTLYSQAIHFANRMVSLLIPLDVNVDAASKPKPAFRLEENQSVSNSIMGSHSLSEHSDEGFEENNALEIGVTVGKTISRFIDCVCTEGGVTSEHIRNLHDMVPGVVHMHIESLEPVYLEAKRHPHVQKPKIQTPCLLPGEDLVTDHLRCFLMPDGREDETQCLIPAEGALFLTNYRVIFKGSPCDPLFCEQVIVRTFPIASLLKEKKISVLYLAHLDQTLTEGLQLRSSSFQLIKVAFDPEVTPEQIESFRKILSKARHPFDEFEYFAFQSYGTMLQGVAPLKTKEKYSTLKGFAKKTLLRGAKKAGFKQKQQTKRKLVSDYDYGSADAQETQSIDDELEDGDEFETQNNAMPRLLTTKDVERMRERSYVQDWKRLGFDAESQRGFRISNANTSYATCRSYPAIIVAPVQCSDAAIMHLGRCFKGQRIPLPTWRHANGALLIRGGQPNSKSVIGMLKNTTGSTTNAHHDVTHYPEQDKYFLALINTMPKLTPLALNQYSGMNLSMSSLMGHSSSDDRQPLTPELSRKHKNNLDISDGNKSSQGGKGGTMKGNPKNSLAHPFRKMRLYALGEKSQAKSNMNVDFCADFIPVDYPDIRQSRPAFKKLIRACMPSHNTNEADGQSFAKMVEQSDWLQQISSLMQLSGAVVDLIDLQESSVMLSLEDGSDVTAQLSSIAQLCLDPYYRSLDGFRVLVEKEWLAFGHRFAHRSNLKPSHANTNIAFAPTFLQFLDVVHQLQRQFPMAFEFNDFYLRFLAYHSVSCRFRTFLFDCELERSDSGIAAMEDKRGSLNAKHMFGAGGMATNGSDDECSVYPLDIRSQRAPAPLNRIGHSIFDYIERQHNKTPIFYNFLYSGDKSVTLRPQNNVAALDLWCYYTNEELAQGAPYDLEVTTVDDEIDLSETKGKRMVITAGYDNMEKCNPSAYVCLLSEVKQAETERGHLPQKWLQVWNSLEVPQLEPVARNTSLGNIFVQTHQHKRSTLEIIMKGRLAGYQDKYFHPHRFEKHPYTTPTNCNHCTKLLWGPVGYRCMDCGNSYHEKCTEHSMKNCTKYKAIDGAVGPPNVNMSQGDTASIASSAATTARTSSHHFYNQFSSNVAENRTHEGHLYKRGALLKGWKQRWFVLDSIKHQLRYYDTSEDTAPKGIIELAEVQSVTAAQPAQIGAKGVDEKGFFDLKTSKRIYNFYAINANLAQEWIEKLQACLQ", "length": 1993 }, "evidence": [ { "id": "HGNC:2135", "url": "https://alliancegenome.org/gene/HGNC:2135#orthology", "database": "AGR" }, { "id": "MGI:1921831", "url": "https://alliancegenome.org/gene/MGI:1921831#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7F4G2", "url": "https://www.uniprot.org/uniprotkb/E7F4G2" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7F4G2", "url": "https://www.uniprot.org/uniprotkb/E7F4G2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "guanyl-nucleotide exchange factor activity", "id": "GO:0005085", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005085", "evidence": [ { "database": "UniProtKB", "id": "E7F4G2", "url": "https://www.uniprot.org/uniprotkb/E7F4G2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1130, "end_pos": 1132, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1250, "end_pos": 1252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1257, "end_pos": 1259, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1629, "end_pos": 1631, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1792, "end_pos": 1794, "annotation": "n_glycosylation_sequon" }, { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F4G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F4G2" }, { "id": "PS51339", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51339" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myotubularin phosphatase", "eco_id": "ECO_0000259", "start_pos": 1109, "end_pos": 1637, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7F4G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F4G2" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 1792, "end_pos": 1896, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7F4G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F4G2" }, { "id": "PS50211", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50211" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UDENN", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 431, "start_aa": "Asp", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 485 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1130, "end_pos": 1132 }, { "start_pos": 1250, "end_pos": 1252 }, { "start_pos": 1257, "end_pos": 1259 }, { "start_pos": 1629, "end_pos": 1631 }, { "start_pos": 1792, "end_pos": 1794 }, { "start_pos": 193, "end_pos": 195 }, { "start_pos": 567, "end_pos": 569 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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Classification" ] }, { "id": "PTHR15635:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15635:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005157707", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157707", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9QPU7", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QPU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9QPU7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9QPU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QCF9", "url": "https://www.uniprot.org/uniprotkb/F1QCF9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QCF9-1", "url": "https://www.uniprot.org/uniprotkb/F1QCF9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1R420", "url": "https://www.uniprot.org/uniprotkb/F1R420", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1R420-1", "url": "https://www.uniprot.org/uniprotkb/F1R420-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060929-520", "url": "https://zfin.org/ZDB-GENE-060929-520", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSAVVDLKTKEEKDAELDKRIEALRKKNEALVKRYQEIQEDKKKAEQEGIAVTTARKPRPHEHESERRKTEKENFTVTVDLSKPAGEKRFTNDRKPAGPRGDPGPEEEEPGRPHGESPPNRTGSGRLSRGGQRRERREPRPNKGEPRPDRQPQDGEVGESPAHTERSSRGGRRGGRGGGGGGGGMQAGPGSDRKSKEWEEKRRQNIEKMNEEMEKIAEYERGQRADGEKIPMRNFLDDPRRSGPIPDTDRKEGSRRHVRNWGGVDFDNVKTGPEVEKEWTNRRPGGKGSVDMTLSMTGRERAEYLRWKKEREQIDEERLARHRNATGQWRREWDAQKTDTMFKEESAVAGESMQEQSNRRAARGRNTHAQQRGAPSEDNKKPPKTPTFGDFLGQGKPRQAGGRGRGKGKSYSMHDNRWEGENEEEKGRKEEQEKEKDEEKDKEKENENEDSTLKAPLSEKKTEEEEEDEWEDASDGEEEDVEEDEKADHEEDTKDAKSKEKSISSAASSTPSPKGQRTPRPKVHIPSPKEMLSTPEAAKPPSPFSPLDGHQPVSDWGEEMEMLSPKSSLGESPLRPSSTESSPAQAKSNPAEKDATDTHSHSEESEITPTVVDSTSCETKKESLRAKSPDTTTSSSQEPIVSPTSDSTSQSKEIDVPNVELDQSQCETSPEEETSVDSSEQPSTG", "length": 685, "header": "tr|F1QCF9-1|F1QCF9_DANRE Isoform 1 of Coiled-coil domain-containing protein 9 isoform X1 OS=Danio rerio OX=7955 GN=ccdc9 PE=1 SV=3 CANONICAL=F1QCF9-1" }, "isoforms": [ { "isoform_ac": "A0A8M9QPU7-1", "url": "https://www.uniprot.org/uniprotkb/F1QCF9/entry#A0A8M9QPU7-1", "sequence": { "sequence": "MSAVVDLKTKEEKDAELDKRIEALRKKNEALVKRYQEIQEDKKKAEQEGIAVTTARKPRPHEHESERRKTEKENFTVTVDLSKPAGEKRFTNDRKPAGPRGDPGPEEEEPGRPHGESPPNRTGSGRLSRGGQRRERREPRPNKGEPRPDRQPQDGEVGESPAHTERSSRGGRRGGRGGGGGGGGMQAGPGSDRKSKEWEEKRRQNIEKMNEEMEKIAEYERGQRADGEKIPMRNFLDDPRRSGPIPDTDRKEGSRRHVRNWGGVDFDNVKTGPEVEKEWTNRRPGGKGSVDMTLSMTGRERAEYLRWKKEREQIDEERLARHRNATGQWRREWDAQKTDTMFKEESAVAGESMQEQSNRRARGRNTHAQQRGAPSEDNKKPPKTPTFGDFLGQGKPRQAGGRGRGKGKSYSMHDNRWEGENEEEKGRKEEQEKEKDEEKDKEKENENEDSTLKAPLSEKKTEEEEEDEWEDASDGEEEDVEEDEKADHEEDTKDAKSKEKSISSAASSTPSPKGQRTPRPKVHIPSPKEMLSTPEAAKPPSPFSPLDGHQPVSDWGEEMEMLSPKSSLGESPLRPSSTESSPAQAKSNPAEKDATDTHSHSEESEITPTVVDSTSCETKKESLRAKSPDTTTSSSQEPIVSPTSDSTSQSKEIDVPNVELDQSQCETSPEEETSVDSSEQPSTG", "length": 684, "header": "tr|A0A8M9QPU7-1|F1QCF9_DANRE Computationally mapped isoform of Coiled-coil domain-containing protein 9 isoform X1 OS=Danio rerio OX=7955 GN=ccdc9 PE=1 SV=1 CANONICAL=F1QCF9-1" }, "locus": {} }, { "isoform_ac": "F1QCF9-1", "url": "https://www.uniprot.org/uniprotkb/F1QCF9/entry#F1QCF9-1", "sequence": { "sequence": "MSAVVDLKTKEEKDAELDKRIEALRKKNEALVKRYQEIQEDKKKAEQEGIAVTTARKPRPHEHESERRKTEKENFTVTVDLSKPAGEKRFTNDRKPAGPRGDPGPEEEEPGRPHGESPPNRTGSGRLSRGGQRRERREPRPNKGEPRPDRQPQDGEVGESPAHTERSSRGGRRGGRGGGGGGGGMQAGPGSDRKSKEWEEKRRQNIEKMNEEMEKIAEYERGQRADGEKIPMRNFLDDPRRSGPIPDTDRKEGSRRHVRNWGGVDFDNVKTGPEVEKEWTNRRPGGKGSVDMTLSMTGRERAEYLRWKKEREQIDEERLARHRNATGQWRREWDAQKTDTMFKEESAVAGESMQEQSNRRAARGRNTHAQQRGAPSEDNKKPPKTPTFGDFLGQGKPRQAGGRGRGKGKSYSMHDNRWEGENEEEKGRKEEQEKEKDEEKDKEKENENEDSTLKAPLSEKKTEEEEEDEWEDASDGEEEDVEEDEKADHEEDTKDAKSKEKSISSAASSTPSPKGQRTPRPKVHIPSPKEMLSTPEAAKPPSPFSPLDGHQPVSDWGEEMEMLSPKSSLGESPLRPSSTESSPAQAKSNPAEKDATDTHSHSEESEITPTVVDSTSCETKKESLRAKSPDTTTSSSQEPIVSPTSDSTSQSKEIDVPNVELDQSQCETSPEEETSVDSSEQPSTG", "length": 685, "header": "tr|F1QCF9-1|F1QCF9_DANRE Isoform 1 of Coiled-coil domain-containing protein 9 isoform X1 OS=Danio rerio OX=7955 GN=ccdc9 PE=1 SV=3 CANONICAL=F1QCF9-1" }, "locus": {} }, { "isoform_ac": "F1R420-1", "url": "https://www.uniprot.org/uniprotkb/F1QCF9/entry#F1R420-1", "sequence": { "sequence": "MSAVVDLKTKEEKDAELDKRIEALRKKNEALVKRYQEIQEDKKKAEQEGIAVTTARKPRPHEHESERRKTEKENFTVTVDLSKPAGEKRFTNDRKPAGPRGDPGPEEEEPGRPHGESPPNRTGSGRLSRGGQRRERREPRPNKGEPRPDRQPQDGEVGESPAHTERSSRGGRRGGRGGGGGGGGMQAGPGSDRKSKEWEEKRRQNIEKMNEEMEKIAEYERGQRADGEKIPMRNFLDDPRRSGPIPDTDRKEGSRRHVRNWGGVDFDNVKTGPEVEKEWTNRRPGGKGSVDMTLSMTGRERAEYLRWKKEREQIDEERLARHRNATGQWRREWDAQKTDTMFKEESAVAGESMQEQSNRREDNKKPPKTPTFGDFLGQGKPRQAGGRGRGKGKSYSMHDNRWEGENEEEKGRKEEQEKEKDEEKDKEKENENEDSTLKAPLSEKKTEEEEEDEWEDASDGEEEDVEEDEKADHEEDTKDAKSKEKSISSAASSTPSPKGQRTPRPKVHIPSPKEMLSTPEAAKPPSPFSPLDGHQPVSDWGEEMEMLSPKSSLGESPLRPSSTESSPAQAKSNPAEKDATDTHSHSEESEITPTVVDSTSCETKKESLRAKSPDTTTSSSQEPIVSPTSDSTSQSKEIDVPNVELDQSQCETSPEEETSVDSSEQPSTG", "length": 669, "header": "tr|F1R420-1|F1R420_DANRE Computationally mapped isoform of Coiled-coil domain-containing protein 9 OS=Danio rerio OX=7955 GN=ccdc9 PE=1 SV=1 CANONICAL=F1QCF9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 510, "start_aa": "Thr", "end_pos": 510, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr510", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "F1R420", "url": "https://www.uniprot.org/uniprotkb/F1R420" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "The first characterization of multidrug and toxin extrusion (MATE/SLC47) proteins in zebrafish (Danio rerio).", "journal": "Sci. Rep.", "date": "2016", "authors": "Lon\u010dar Jovica, Popovi\u0107 Marta, Krznar Petra, Zaja Roko, Smital Tvrtko", "evidence": [ { "database": "UniProtKB", "id": "F1R420", "url": "https://www.uniprot.org/uniprotkb/F1R420" } ], "reference": [ { "type": "PubMed", "id": "27357367", "url": "https://glygen.org/publication/PubMed/27357367" } ] } ], "pathway": [ { "id": "dre:550140", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:550140", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ABU0-1", "protein_name": "Coiled-coil domain containing 9", "gene_name": "CCDC9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSATLDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKENVAVGTEKTLGPSRRSPGTPRPPGASKGGRIPPQQGGRAGMGRASRSWEDSPGEQLRGGAGGRGRRGRGRGSPRLAGAGDASTADRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEEPERDRREGSRRHGRNWGGSDFERVRCGLEQERQGRRAGLGGAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPAAAPELSHRYDDQAWARPPKPPTFREFLSQHKAEVSRRRRKSSRPQAKAVPGAYSDHDDRWESKEAVSPAPEPPQPVRPEEPPTQLPETPTPAHQPPEDEGEEYEGEAGDGEDEEWEDVSEEEEIEEEEAEEEEEEEPAPTGDHQPHKAEPSGSPAREHADQEPARPEEPLPPPQAPATPSSPFSPSGGHQPVSDWGEEMELNSPRTPHPADALSPGGDPPASASLESGPSLPGTQKAEEEGSEAAPEAGREGQETAISDFQRASPNS", "length": 573 }, "evidence": [ { "id": "F1QCF9", "url": "https://omabrowser.org/oma/group/F1QCF9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F6QX85-1", "protein_name": "Coiled-coil domain containing 9", "gene_name": "CCDC9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSAALDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTGPRKSRSVEKENVAVEKNLGPSRRSPGTPRPPGVSKGGRIPPQHGGRAGMGRTSRSWEDSPGEQPRGGAGGRSRRGRGRGSPHLSGGGDASTADRKSKEWEERRKQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEEPERDRREGSRRHGRNWGGSDFERVRYGLEQERQGRRAGLGGAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPAVALEPSHRYDDQAWARPPKPPTFREFLSQHKTEVSRRKKKSSRPQPKAAPRAYSDHDDRWEMKEAMSTAPEPPQPALPKEAPTQLPETPAPAHRPPEDEGEEGEDEGEDEEWEDVSEDEEEEEEIEEEEEADDEEEEPAGDHQPQEAEPSGSPAREHGDKETARPEEPLPLPQAPATPSSPFSPPGGHQPVSDWGEEMELNSPRTAHPADAVSPGGDQPAPASLESGPSAPGAQKAEEEGSEAAPEADPEGQETAEIADFQRVRFCKVVAAASPPGAAR", "length": 583 }, "evidence": [ { "id": "F1QCF9", "url": "https://omabrowser.org/oma/group/F1QCF9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "M0RA86-1", "protein_name": "Coiled-coil domain containing 9", "gene_name": "Ccdc9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRPSSGATRCPSPALETPSPLLPAEIEEDRKKAELEGVAVTAPRKSRSMEKENMAVEEKNLGPSRRTPGTPRPPGASRGGRTHPQQGGRAGVGRASRGWEDGAGEQLRGGTGGRGRRGRGRGSPHLLGAGDNSTSDRKSKEWEERRRQNIEKMNEEMERIAEYERNQREGVLEPNPVRNFLDDPRRRGGPLEESERDRREGSRRHGRNWGGSDFERVRSGLEQERQGRRAGLGSGGDMTMSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPAPTHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEVNSRRRRKNSRPQAKVAPRAYSDHDNRWETKEEAVSPAPKSSQSMSLEETPTQPPETPAPAHRPPEEDGEEDVGEEEEGEEEGEDDDEDEEWEDVSEDVTEEEEEEEEEFEEEEESPKEQEAAAVPDHQPEAEPAGKPTCEQVDPVPAGPQELLSPVPVEPPSPFSPSEDHQPVSDWGGDQPALASLESRPTLAGTLKSEEEGSEASPGGMHEAGGEVVGPEGQETAEITDFQRSRNPEDAGGRGGSAGLPGSQAGCSPPCSPPWILRL", "length": 595 }, "evidence": [ { "id": "MGI:1921443", "url": "https://alliancegenome.org/gene/MGI:1921443#orthology", "database": "AGR" }, { "id": "HGNC:24560", "url": "https://alliancegenome.org/gene/HGNC:24560#orthology", "database": "AGR" }, { "id": "F1QCF9", "url": "https://omabrowser.org/oma/group/F1QCF9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8VC31-1", "protein_name": "Coiled-coil domain-containing protein 9", "gene_name": "Ccdc9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MATTLDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKSRSMEKENMAVEEKSLGPSRRTPGTPRPPGASRGGRTHPQQGGRAGVGRASQGWEDGAGEQLRGGPGGRGRRGRGRGSPHLLGAGDNSTSDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRGGPLEESERDRREGSRRHGRNWGGSDFERVRSGLEQERQGRRAGLGSGGDMTMSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPAPTHELSHRYDDQAWARPPKPPTFGEFLSQHKAEVSSRRRRKNSRPQAKVAPRAYSDHDNRWETREEAVSSAPESSQSISLEETPTQASETPAPAHRPPEEDGEEDVGEEEEGEEEGEDEEDEEWEDVSEDVTEEEEEEEEEFEEDEEGPKDQEAATVPDHQPEAEPAGKPTCEQVDPVPAGSQELLSPVPVEPPIPFSPSEDHQPVSDWGEEMELNSPGTAHLPGTHSSGEAWPFANA", "length": 543 }, "evidence": [ { "id": "MGI:1921443", "url": "https://alliancegenome.org/gene/MGI:1921443#orthology", "database": "AGR" }, { "id": "HGNC:24560", "url": "https://alliancegenome.org/gene/HGNC:24560#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-520", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-520#orthology", "database": "AGR" }, { "id": "F1QCF9", "url": "https://omabrowser.org/oma/group/F1QCF9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y3X0-1", "protein_name": "Coiled-coil domain-containing protein 9", "gene_name": "CCDC9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAATLDLKSKEEKDAELDKRIEALRRKNEALIRRYQEIEEDRKKAELEGVAVTAPRKGRSVEKENVAVESEKNLGPSRRSPGTPRPPGASKGGRTPPQQGGRAGMGRASRSWEGSPGEQPRGGGAGGRGRRGRGRGSPHLSGAGDTSISDRKSKEWEERRRQNIEKMNEEMEKIAEYERNQREGVLEPNPVRNFLDDPRRRSGPLEESERDRREESRRHGRNWGGPDFERVRCGLEHERQGRRAGLGSAGDMTLSMTGRERSEYLRWKQEREKIDQERLQRHRKPTGQWRREWDAEKTDGMFKDGPVPAHEPSHRYDDQAWARPPKPPTFGEFLSQHKAEASSRRRRKSSRPQAKAAPRAYSDHDDRWETKEGAASPAPETPQPTSPETSPKETPMQPPEIPAPAHRPPEDEGEENEGEEDEEWEDISEDEEEEEIEVEEGDEEEPAQDHQAPEAAPTGIPCSEQAHGVPFSPEEPLLEPQAPGTPSSPFSPPSGHQPVSDWGEEVELNSPRTTHLAGALSPGEAWPFESV", "length": 531 }, "evidence": [ { "id": "MGI:1921443", "url": "https://alliancegenome.org/gene/MGI:1921443#orthology", "database": "AGR" }, { "id": "HGNC:24560", "url": "https://alliancegenome.org/gene/HGNC:24560#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060929-520", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-520#orthology", "database": "AGR" }, { "id": "F1QCF9", "url": "https://omabrowser.org/oma/group/F1QCF9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 120, "end_pos": 122, "annotation": "n_glycosylation_sequon" }, { "start_pos": 324, "end_pos": 326, "annotation": "n_glycosylation_sequon" }, { "start_pos": 74, "end_pos": 76, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 510 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 120, "end_pos": 122 }, { "start_pos": 324, "end_pos": 326 }, { "start_pos": 74, "end_pos": 76 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1Q543-1", "uniprot_ac": "F1Q543", "uniprot_id": "F1Q543_DANRE", "mass": { "chemical_mass": 74408.0, "monoisotopic_mass": 74408.0 }, "refseq": { "ac": "XP_009302592", "name": "centrosomal protein of 78 kDa isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302592" }, "gene_names": [ { "name": "cep78", "type": "recommended", "evidence": [ { "id": "F1Q543", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q543" } ] }, { "name": "cep78", "type": "synonym", "evidence": [ { "id": "XP_009302592", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302592" } ] } ], "protein_names": [ { "name": "Centrosomal protein of 78 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "F1Q543", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q543/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 78 kDa isoform X1", "type": "synonym", "evidence": [ { "id": "XP_009302592", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302592" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009302592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302592" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q543", "url": "https://www.uniprot.org/uniprotkb/F1Q543" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cep78", "url": "https://www.uniprot.org/uniprotkb/F1Q543", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070905-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070905-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000039229", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000039229", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "564741", "url": "https://www.ncbi.nlm.nih.gov/gene/564741", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026212", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026212", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564741", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564741", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MTLKLCK", "url": "https://omabrowser.org/oma/group/MTLKLCK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7TF73", "url": "https://www.orthodb.org/?gene=A0A8N7TF73", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1Q543", "url": "https://www.orthodb.org/?gene=F1Q543", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24110", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24110", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24110:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24110:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_009302592", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009302592", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7TF73", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TF73", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7TF73-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7TF73-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GC97", "url": "https://www.uniprot.org/uniprotkb/A0AC58GC97", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GC97-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GC97-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GC98", "url": "https://www.uniprot.org/uniprotkb/A0AC58GC98", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GC98-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GC98-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q543", "url": "https://www.uniprot.org/uniprotkb/F1Q543", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q543-1", "url": "https://www.uniprot.org/uniprotkb/F1Q543-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070905-1", "url": "https://zfin.org/ZDB-GENE-070905-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLEPAQSRRRGAQDFEGYYDHLCAAQGSAPVRAVKACLSRGVLEFNPDQLSLADWTPVLSALAINKHLHQVSIRSCHLLSTGAQNVYRPHNKKKTPAIHSKTVSLQLCKAVQKCLCESSSLRTLQLHALPLRERDLTALTKGLAKSVSLEHLSLAHCPIGDQGLEVICQSVKYSSTIKGVDFTSCNITWQGAEHMANIIKHQAMRRHSTAWVETLRYRRAEFEAMNGLRRITLNDNILIGDRGVSALARELTEDLWVKAVDLQRCGISNDGAQVLEQMLQSNSTLCVLDIRRNPLIDNNVVKAVLKKVLMNTKNLDSQYLWLKPPSPKDSADQSRQFRRKNAGKATYRIGSRRSSSVISVFRPPRPGSTGYIPWRTAARADLQRGASRADGRTDQSFQNATSVQVTVETESESEDVEAKDVESPLEKITSYQFRRLQTENNRLKVELEECRLRLAEERNTRLKANSRLVELELENERLRTMNQSLSEAHISSSVLEDERVLESIESSFHKFHAFLDLLKDAGLGQFASMAGIEQSDFGVVGRPQLSSTERTHTGPARHEDRRNSSAPVDVPHPESGTRPEPPADTEDLPQPRPHQEELLHPVISSRSSPALQELDLRAGSGSGGSVSSVSLQSRGSPSSRSVYSRASSVSRSGSDRPSASGSQRNTAGLIGF", "length": 672, "header": "tr|F1Q543-1|F1Q543_DANRE Isoform 1 of Centrosomal protein of 78 kDa isoform X1 OS=Danio rerio OX=7955 GN=cep78 PE=4 SV=1 CANONICAL=F1Q543-1" }, "isoforms": [ { "isoform_ac": "A0A8N7TF73-1", "url": "https://www.uniprot.org/uniprotkb/F1Q543/entry#A0A8N7TF73-1", "sequence": { "sequence": "MLEPAQSRRRGAQDFEGYYDHLCAAQGSAPVRAVKACLSRGVLEFNPDQLSLADWTPVLSALAINKHLHQVSIRSCHLLSTGAQNVYRPHNKKKTPAIHSKTVSLQLCKAVQKCLCESSSLRTLQLHALPLRERDLTALTKGLAKSVSLEHLSLAHCPIGDQGLEVICQSVKYSSTIKGVDFTSCNITWQGAEHMANIIKHQAMRRHSTAWVETLRYRRAEFEAMNGLRRITLNDNILIGDRGVSALARELTEDLWVKAVDLQRCGISNDGAQVLEQMLQSNSTLCVLDIRRNPLIDNNVVKAVLKKVLMNTKNLDSQYLWLKPPSPKDSADQSRQFRRKNAGKATYRIGSRRSSSVISVFRPPRPGSTGYIPWRTAARADLQRGASRADGRTDQSFQVTVETESESEDVEAKDVESPLEKITSYQFRRLQTENNRLKVELEECRLRLAEERNTRLKANSRLVELELENERLRTMNQSLSEAHISSSVLEDERVLESIESSFHKFHAFLDLLKDAGLGQFASMAGIEQSDFGVVGRPQLSSTERTHTGPARHEDRRNSSAPVDVPHPESGTRPEPPADTEDLPQPRPHQEELLHPVISSRSSPALQELDLRAGSGSGGSVSSVSLQSRGSPSSRSVYSRASSVSRSGSDRPSASGSQRNTAGLIGF", "length": 666, "header": "tr|A0A8N7TF73-1|F1Q543_DANRE Computationally mapped isoform of Centrosomal protein of 78 kDa isoform X1 OS=Danio rerio OX=7955 GN=cep78 PE=4 SV=1 CANONICAL=F1Q543-1" }, "locus": {} }, { "isoform_ac": "A0AC58GC97-1", "url": "https://www.uniprot.org/uniprotkb/F1Q543/entry#A0AC58GC97-1", "sequence": { "sequence": "MLEPAQSRRRGAQDFEGYYDHLCAAQGSAPVRAVKACLSRGVLEFNPDQLSLADWTPVLSALAINKHLHQVSIRSCHLLSTGAQNVYRPHNKKKTPAIHSKTVSLQLCKAVQKCLCESSSLRTLQLHALPLRERDLTALTKGLAKSVSLEHLSLAHCPIGDQGLEVICQSVKYSSTIKGVDFTSCNITWQGAEHMANIIKHQAMRRHSTAWVETLRYRRAEFEAMNGLRRITLNDNILIGDRGVSALARELTEDLWVKVDLQRCGISNDGAQVLEQMLQSNSTLCVLDIRRNPLIDNNVVKAVLKKVLMNTKNLDSQYLWLKPPSPKDSADQSRQFRRKNAGKATYRIGSRRSSSVISVFRPPRPGSTGYIPWRTAARADLQRGASRADGRTDQSFQVTVETESESEDVEAKDVESPLEKITSYQFRRLQTENNRLKVELEECRLRLAEERNTRLKANSRLVELELENERLRTMNQSLSEAHISSSVLEDERVLESIESSFHKFHAFLDLLKDAGLGQFASMAGIEQSDFGVVGRPQLSSTERTHTGPARHEDRRNSSAPVDVPHPESGTRPEPPADTEDLPQPRPHQEELLHPVISSRSSPALQELDLRAGSGSGGSVSSVSLQSRGSPSSRSVYSRASSVSRSGSDRPSASGSQRNTAGLIGF", "length": 665, "header": "tr|A0AC58GC97-1|A0AC58GC97_DANRE Computationally mapped isoform of Centrosomal protein of 78 kDa isoform X4 OS=Danio rerio OX=7955 GN=cep78 PE=4 SV=1 CANONICAL=F1Q543-1" }, "locus": {} }, { "isoform_ac": "A0AC58GC98-1", "url": "https://www.uniprot.org/uniprotkb/F1Q543/entry#A0AC58GC98-1", "sequence": { "sequence": "MLEPAQSRRRGAQDFEGYYDHLCAAQGSAPVRAVKACLSRGVLEFNPDQLSLADWTPVLSALAINKHLHQVSIRSCHLLSTGAQNVYRPHNKKKTPAIHSKTVSLQLCKAVQKCLCESSSLRTLQLHALPLRERDLTALTKGLAKSVSLEHLSLAHCPIGDQGLEVICQSVKYSSTIKGVDFTSCNITWQGAEHMANIIKHQAMRRHSTAWVETLRYRRAEFEAMNGLRRITLNDNILIGDRGVSALARELTEDLWVKVDLQRCGISNDGAQVLEQMLQSNSTLCVLDIRRNPLIDNNVVKAVLKKVLMNTKNLDSQYLWLKPPSPKDSADQSRQFRRKNAGKATYRIGSRRSSSVISVFRPPRPGSTGYIPWRTAARADLQRGASRADGRTDQSFQNATSVQVTVETESESEDVEAKDVESPLEKITSYQFRRLQTENNRLKVELEECRLRLAEERNTRLKANSRLVELELENERLRTMNQSLSEAHISSSVLEDERVLESIESSFHKFHAFLDLLKDAGLGQFASMAGIEQSDFGVVGRPQLSSTERTHTGPARHEDRRNSSAPVDVPHPESGTRPEPPADTEDLPQPRPHQEELLHPVISSRSSPALQELDLRAGSGSGGSVSSVSLQSRGSPSSRSVYSRASSVSRSGSDRPSASGSQRNTAGLIGF", "length": 671, "header": "tr|A0AC58GC98-1|A0AC58GC98_DANRE Computationally mapped isoform of Centrosomal protein of 78 kDa isoform X2 OS=Danio rerio OX=7955 GN=cep78 PE=4 SV=1 CANONICAL=F1Q543-1" }, "locus": {} }, { "isoform_ac": "F1Q543-1", "url": "https://www.uniprot.org/uniprotkb/F1Q543/entry#F1Q543-1", "sequence": { "sequence": "MLEPAQSRRRGAQDFEGYYDHLCAAQGSAPVRAVKACLSRGVLEFNPDQLSLADWTPVLSALAINKHLHQVSIRSCHLLSTGAQNVYRPHNKKKTPAIHSKTVSLQLCKAVQKCLCESSSLRTLQLHALPLRERDLTALTKGLAKSVSLEHLSLAHCPIGDQGLEVICQSVKYSSTIKGVDFTSCNITWQGAEHMANIIKHQAMRRHSTAWVETLRYRRAEFEAMNGLRRITLNDNILIGDRGVSALARELTEDLWVKAVDLQRCGISNDGAQVLEQMLQSNSTLCVLDIRRNPLIDNNVVKAVLKKVLMNTKNLDSQYLWLKPPSPKDSADQSRQFRRKNAGKATYRIGSRRSSSVISVFRPPRPGSTGYIPWRTAARADLQRGASRADGRTDQSFQNATSVQVTVETESESEDVEAKDVESPLEKITSYQFRRLQTENNRLKVELEECRLRLAEERNTRLKANSRLVELELENERLRTMNQSLSEAHISSSVLEDERVLESIESSFHKFHAFLDLLKDAGLGQFASMAGIEQSDFGVVGRPQLSSTERTHTGPARHEDRRNSSAPVDVPHPESGTRPEPPADTEDLPQPRPHQEELLHPVISSRSSPALQELDLRAGSGSGGSVSSVSLQSRGSPSSRSVYSRASSVSRSGSDRPSASGSQRNTAGLIGF", "length": 672, "header": "tr|F1Q543-1|F1Q543_DANRE Isoform 1 of Centrosomal protein of 78 kDa isoform X1 OS=Danio rerio OX=7955 GN=cep78 PE=4 SV=1 CANONICAL=F1Q543-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:564741", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564741", "resource": "KEGG Pathway" }, { "id": "R-DRE-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" } ], "orthologs": [ { "uniprot_canonical_ac": "F1LP29-1", "protein_name": "Centrosomal protein of 78 kDa", "gene_name": "Cep78", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIDSVKLRRDCATDFFSHYEYLCALQDSAPLPAVRACLRDGVLDFNADRLRAVDWAPLLSSLRVNRDLPLVAIKSSFQPWLGESVLRSGGADAHRVCRNRVPSVRSKDISFQLCKALKGCLSVSGVLRNLELNGLILRERDLTSLTKGLSKSASLVHLSLANCPVGDGGLEIICQGIKNSVTLKTVNFTGCNLTWQGASHMAKILKYQTMRRHEETWAESLRYRRPDLDCMAGLRRITLNCNTLIGDQGASAFADSLSEDLWLRALDLQQCGLTSEGAKALLEALETNRTLVVLDIRKNPLIDHSMMKAVIRKVLQNGRSATSEYQWVTSPSLKELPKTTKQKKKTIVLGSSRKGKATIRVGLATKKPVSNGRKHGLSKDSYAPDPLPPGASGFLPWRTAERARRNRSFPLIKTHDLSNHLQQSDFPVTVTVESPSSSETDESEDSSESVHEVPQKTSIRQETLQEKLEECLKQLKEERVTRLKTDKRISELEHENAQLRNINFSLSEALQAQSLTSMILDDEGVLGSIENSFQKFHAFLDLLKDAGLGQLATMAGIDQSDFHLLGRPQMSSTVNTPVEEQKGLEDENLDLKQTAVGQMQDIGFQKITSDPMVPLPLDTNQVPASTQEAAGSSRDHLGVVALEQQEGSAVGFIAITGSPSADGISGGRSLEEVVLSKHSRSSSGKGSTASEPSRRQSAERHSRKDLHSDSDSPVNSKGKGPGEKRSLLNEPIKSESLKKCVSIKKENRIVTVSSKSIKSKPNLLEHSESDTIGSDFEFQEHDHSSAHLT", "length": 789 }, "evidence": [ { "id": "MGI:1924386", "url": "https://alliancegenome.org/gene/MGI:1924386#orthology", "database": "AGR" }, { "id": "HGNC:25740", "url": "https://alliancegenome.org/gene/HGNC:25740#orthology", "database": "AGR" }, { "id": "F1Q543", "url": "https://omabrowser.org/oma/group/F1Q543/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5JTW2-1", "protein_name": "Centrosomal protein of 78 kDa", "gene_name": "CEP78", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIDSVKLRRDSAADFFSHYEYLCALQNSVPLPAVRACLREGVLDFNADRLRGVDWAPLLSTLKINKDLPLVSIKSFFQPWLGDTGSDMNKFCRSRVPAIRYKDVTFQLCKALKGCLSISSVLKNLELNGLILRERDLTILAKGLNKSASLVHLSLANCPIGDGGLEIICQGIKSSITLKTVNFTGCNLTWQGADHMAKILKYQTMRRHEETWAESLRYRRPDLDCMAGLRRITLNCNTLIGDLGACAFADSLSEDLWLRALDLQQCGLTNEGAKALLEALETNTTLVVLDIRKNPLIDHSMMKAVIKKVLQNGRSAKSEYQWITSPSVKEPSKTAKQKRRTIILGSGHKGKATIRIGLATKKPVSSGRKHSLGKEYYAPAPLPPGVSGFLPWRTAERAKRHRGFPLIKTRDICNQLQQPGFPVTVTVESPSSSEVEEVDDSSESVHEVPEKTSIEQEALQEKLEECLKQLKEERVIRLKVDKRVSELEHENAQLRNINFSLSEALHAQSLTNMILDDEGVLGSIENSFQKFHAFLDLLKDAGLGQLATMAGIDQSDFQLLGHPQMTSTVSNPPKEEKKALEDEKPEPKQNALGQMQNIQFQKITGDARIPLPLDSFPVPVSTPEGLGTSSNNLGVPATEQRQESFEGFIARMCSPSPDATSGTGSQRKEEELSRNSRSSSEKKTKTESH", "length": 689 }, "evidence": [ { "id": "MGI:1924386", "url": "https://alliancegenome.org/gene/MGI:1924386#orthology", "database": "AGR" }, { "id": "HGNC:25740", "url": "https://alliancegenome.org/gene/HGNC:25740#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070905-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070905-1#orthology", "database": "AGR" }, { "id": "F1Q543", "url": "https://omabrowser.org/oma/group/F1Q543/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6IRU7-1", "protein_name": "Centrosomal protein of 78 kDa", "gene_name": "Cep78", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIDSVKLRRDCAADFFSHYEYLCALQDSVPLPAVRACLRDGVLDFNADRLRAVDWAPLLSTLRVNRDLPLVAIKSSFQPWLGETVLRSGGADTHRICRNRVPAVRSKDISFQLCKALRGCLSVSGVLRNLELNGLILRERDLTSLTKGLSKSTSLVHLSLANCPIGDGGLEIICQGIKNSVTLKTVNFTGCNLTWQGACHMAKILKYQTMRRHEETWAESLRYRRPDLDCMAGLRRITLNCNTLIGDQGASAFADSLSEDLWLRALDLQQCGLTSEGAKALLEALETNRTLVVLDIRKNPLIDHSMMKAVIKKVLQNGRSADSEYQWVTSPSSKEPSKTAKQRKKTIVLGSSRKGKATIRIGLATKKPSSNGRKQGLGKDCYAPNPLPPGASGFLPWRTAERAKRSRSSSLIKTRDLSNHLKKSDFPVTVTVESPSSSETDETEDSSESVQEAPQKTSIKEETLQEKLEECLRQLKEERVIRLKADKRVSELEHENAQLRNINFSLSEALHAQSLTNMILDDEGVLGSIENSFQKFHAFLDLLKDAGLGQLATMAGIDQSDFHLLGRPQMNSTVNTPIQEQKALEDETLHPKQTATGQMQDIRFQKITSDALIPLPLNTVQDPASAQEAVGASRDHLGVVGLEQQEGSAAGFIAKTGSPLAGGIPGGRSQREEEVLSKHSRSSSEKGSTASEPSRRPSAERHPRKDLLSDADPPGNSESKGPGDRRSLLNEPIKSESLKKCISIKKENRIVTVSSKTIKSKPNLLEHSESDTLGSDFELQERVHSSAHLT", "length": 790 }, "evidence": [ { "id": "MGI:1924386", "url": "https://alliancegenome.org/gene/MGI:1924386#orthology", "database": "AGR" }, { "id": "HGNC:25740", "url": "https://alliancegenome.org/gene/HGNC:25740#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070905-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070905-1#orthology", "database": "AGR" }, { "id": "F1Q543", "url": "https://omabrowser.org/oma/group/F1Q543/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VFH6-1", "protein_name": "Protein Cep78 homolog", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSVSRVTMMRKGHSGEVARKPNTVVVSVPPLVKKSSKSRSFHFRYLELCRAKNLTPVPEIRSKSNATTTFLELCGDKLAVSDWQLLTEALHYDLVLQQLVVRLRRTYPQTNIDPIDTEKRARLFRQRPVIYTRFIFNSLVQAIANCVSSNKNLSVLKLEGLPLQDGYIETIAKALADNECLESVSFRKSNIGDKGCEVVCNTAKYLNRIEVFDLSECGLTSKGAEHVADMLKMQKITRFTEGWEKSLRYRSVDVNTIGGLRTVLLADNPEIGDVGIRWITEVLKEDAWIKKIDMEGCGLTDIGANLILDCLELNTAITEFNVRNNEGISKFLQRSIHDRLGCLPEEKQEPEYDLSCVNGLQSLPKNKKVTVSQLLSHTKALEEQLSFERTLRKKAEKLNEKLSHQLMRPDSNHMVQEKAMEGGSQTNISREYVARNDVMPEVIKNSQSYRQSHFNRLVNSAATSPEVTPRSEIVTLRKEQQLQRQQPPPMEVKHLSLEQQIRNLRDVQKKVDLDVEEEEEEEEEEQQAEESQSESEPQNEEQQHYEQQMQVQRKHLQVRKVRSEIKYVENNPKEAAKKNRESKSDHEFANERDFKLNPSVQFETDIGDNVMVNPGHRYEGGGGDTAYVYNYEHEQQQQPVKRGYEHGYVVGVGDGSHRRQRQSQLVEALVQKRVPGASDGHVAQFVSNLERQANAGKTGKKRLKPRPEDDLQVPVGDMHMESSYMSRSEELSSTDVTLENSDYETEATDSTLLSSSKYSSMHVFVRRKQSESMSLTEEAGDGDAGGGGGSGDFGDQNVISPANVYMSLQLQKQREQSA", "length": 818 }, "evidence": [ { "id": "MGI:1924386", "url": "https://alliancegenome.org/gene/MGI:1924386#orthology", "database": "AGR" }, { "id": "HGNC:25740", "url": "https://alliancegenome.org/gene/HGNC:25740#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "centrosome", "id": "GO:0005813", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005813", "evidence": [ { "database": "UniProtKB", "id": "F1Q543", "url": "https://www.uniprot.org/uniprotkb/F1Q543" } ], "pmid": "" }, { "name": "ciliary basal body", "id": "GO:0036064", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036064", "evidence": [ { "database": "UniProtKB", "id": "F1Q543", "url": "https://www.uniprot.org/uniprotkb/F1Q543" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium organization", "id": "GO:0044782", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044782", "evidence": [ { "database": "UniProtKB", "id": "F1Q543", "url": "https://www.uniprot.org/uniprotkb/F1Q543" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 282, "end_pos": 284, "annotation": "n_glycosylation_sequon" }, { "start_pos": 399, "end_pos": 401, "annotation": "n_glycosylation_sequon" }, { "start_pos": 482, "end_pos": 484, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 282, "end_pos": 284 }, { "start_pos": 399, "end_pos": 401 }, { "start_pos": 482, "end_pos": 484 }, { "start_pos": 563, "end_pos": 565 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0S7W5-1", "uniprot_ac": "B0S7W5", "uniprot_id": "B0S7W5_DANRE", "mass": { "chemical_mass": 55169.0, "monoisotopic_mass": 55169.0 }, "refseq": { "ac": "NP_001119952", "name": "aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119952" }, "gene_names": [ { "name": "aldh9a1a.2", "type": "recommended", "evidence": [ { "id": "B0S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7W5" } ] }, { "name": "aldh9a1a.2", "type": "synonym", "evidence": [ { "id": "NP_001119952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119952" } ] }, { "name": "si:ch211-216k22.8", "type": "synonym", "evidence": [ { "id": "NP_001119952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119952" }, { "id": "B0S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7W5" } ] } ], "protein_names": [ { "name": "Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2", "type": "synonym", "evidence": [ { "id": "B0S7W5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7W5/entry#names_and_taxonomy" } ] }, { "name": "aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2", "type": "synonym", "evidence": [ { "id": "NP_001119952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119952" } ] }, { "name": "aldehyde dehydrogenase 9 family, member A1a.2", "type": "synonym", "evidence": [ { "id": "NP_001119952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119952" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: partial sample support SAMEA3505371, SAMEA3505372 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Jul 31, 2008 this sequence version replaced XP_001923619.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001119952", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119952" } ] }, { "annotation": "Converts gamma-trimethylaminobutyraldehyde into gamma-butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency.", "evidence": [ { "database": "UniProtKB", "id": "B0S7W5", "url": "https://www.uniprot.org/uniprotkb/B0S7W5#function" }, { "database": "UniProtKB", "id": "ARBA00037704", "url": "https://www.uniprot.org/uniprotkb/ARBA00037704#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S7W5", "url": "https://www.uniprot.org/uniprotkb/B0S7W5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "aldh9a1a.2", "url": "https://www.uniprot.org/uniprotkb/B0S7W5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-507", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-507", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000055331", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000055331", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd07090", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd07090", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100006238", "url": "https://www.ncbi.nlm.nih.gov/gene/100006238", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR015590", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015590", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016160", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016160", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016161", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016161", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016162", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016162", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016163", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016163", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029510", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029510", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100006238", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006238", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WFRYNAG", "url": "https://omabrowser.org/oma/group/WFRYNAG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S7W5", "url": "https://www.orthodb.org/?gene=B0S7W5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11699", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11699", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00171", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00171", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001119952", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119952", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "16185", "url": "https://www.rhea-db.org/rhea/16185", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "17985", "url": "https://www.rhea-db.org/rhea/17985", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AC58G5T4", "url": "https://www.uniprot.org/uniprotkb/A0AC58G5T4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G5T4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G5T4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S7W5", "url": "https://www.uniprot.org/uniprotkb/B0S7W5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S7W5-1", "url": "https://www.uniprot.org/uniprotkb/B0S7W5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-507", "url": "https://zfin.org/ZDB-GENE-081104-507", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAQQPLLSLPEFQSVSTGTLVVKEPLNFWAGARVKPSNTKNSEPVYEPATGRVLCDMIPCGEEEVDQAIKSAHSAYLKWSQLSGMERSRIMLEAARIIRERRDAIAKTDVANNGTSITEAKVDIDLAWKCIEYYAGIAPTLSGQHIQLPGGSFAYTRREPLGVCVGIGAWNYPFQIAAWKSAPAIACGNAMVFKPSPMTPVTAVMLAEIYKEAGVPDGLFNVVQGGPETGSLLCHHPMVAKVSLTGGVPTGKKVLEMAAKGVKQVTLELGGKSPLIIFNDCELENAIKGALMANFLTKGEVCCNGTRVFVQREIMPKFLEEVVKRTKAISVGDPLCEGTRMGALISKPHMEKVLGFIKQAKEQGAKVLCGGEQFVPNDPKLKDGYFVSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDIARAHRVIANLQAGMCYINNYNVCPVEVPFGGYKMSGFGKENGALTIEYYSQLKTVVVEMGDVESLF", "length": 508, "header": "tr|B0S7W5-1|B0S7W5_DANRE Isoform 1 of Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2 OS=Danio rerio OX=7955 GN=aldh9a1a.2 PE=1 SV=1 CANONICAL=B0S7W5-1" }, "isoforms": [ { "isoform_ac": "A0AC58G5T4-1", "url": "https://www.uniprot.org/uniprotkb/B0S7W5/entry#A0AC58G5T4-1", "sequence": { "sequence": "MQSQKPMWPTMARPLRRLRWISTLLGSVLSTMLALPPHCQHIQLPGGSFAYTRREPLGVCVGIGAWNYPFQIAAWKSAPAIACGNAMVFKPSPMTPVTAVMLAEIYKEAGVPDGLFNVVQGGPETGSLLCHHPMVAKVSLTGGVPTGKKVLEMAAKGVKQVTLELGGKSPLIIFNDCELENAIKGALMANFLTKGEVCCNGTRVFVQREIMPKFLEEVVKRTKAISVGDPLCEGTRMGALISKPHMEKVLGFIKQAKEQGAKVLCGGEQFVPNDPKLKDGYFVSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDIARAHRVIANLQAGMCYINNYNVCPVEVPFGGYKMSGFGKENGALTIEYYSQLKTVVVEMGDVESLF", "length": 404, "header": "tr|A0AC58G5T4-1|A0AC58G5T4_DANRE Computationally mapped isoform of Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2 isoform X2 OS=Danio rerio OX=7955 GN=aldh9a1a.2 PE=1 SV=1 CANONICAL=B0S7W5-1" }, "locus": {} }, { "isoform_ac": "B0S7W5-1", "url": "https://www.uniprot.org/uniprotkb/B0S7W5/entry#B0S7W5-1", "sequence": { "sequence": "MAQQPLLSLPEFQSVSTGTLVVKEPLNFWAGARVKPSNTKNSEPVYEPATGRVLCDMIPCGEEEVDQAIKSAHSAYLKWSQLSGMERSRIMLEAARIIRERRDAIAKTDVANNGTSITEAKVDIDLAWKCIEYYAGIAPTLSGQHIQLPGGSFAYTRREPLGVCVGIGAWNYPFQIAAWKSAPAIACGNAMVFKPSPMTPVTAVMLAEIYKEAGVPDGLFNVVQGGPETGSLLCHHPMVAKVSLTGGVPTGKKVLEMAAKGVKQVTLELGGKSPLIIFNDCELENAIKGALMANFLTKGEVCCNGTRVFVQREIMPKFLEEVVKRTKAISVGDPLCEGTRMGALISKPHMEKVLGFIKQAKEQGAKVLCGGEQFVPNDPKLKDGYFVSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDIARAHRVIANLQAGMCYINNYNVCPVEVPFGGYKMSGFGKENGALTIEYYSQLKTVVVEMGDVESLF", "length": 508, "header": "tr|B0S7W5-1|B0S7W5_DANRE Isoform 1 of Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 2 OS=Danio rerio OX=7955 GN=aldh9a1a.2 PE=1 SV=1 CANONICAL=B0S7W5-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 199, "start_aa": "Thr", "end_pos": 199, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr199", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "ALDH2 mediates 5-nitrofuran activity in multiple species.", "journal": "Chem. Biol.", "date": "2012", "authors": "Zhou Linna, Ishizaki Hironori, Spitzer Michaela, Taylor Kerrie L, Temperley Nicholas D, Johnson Stephen L, Brear Paul, Gautier Philippe, Zeng Zhiqiang, Mitchell Amy, Narayan Vikram, McNeil Ewan M, Melton David W, Smith Terry K, Tyers Mike, Westwood Nicholas J, Patton E Elizabeth", "evidence": [ { "database": "UniProtKB", "id": "B0S7W5", "url": "https://www.uniprot.org/uniprotkb/B0S7W5" } ], "reference": [ { "type": "PubMed", "id": "22840776", "url": "https://glygen.org/publication/PubMed/22840776" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "B0S7W5", "url": "https://www.uniprot.org/uniprotkb/B0S7W5" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] }, { "title": "The combination of loss of glyoxalase1 and obesity results in hyperglycemia.", "journal": "JCI Insight", "date": "2019", "authors": "Lodd Elisabeth, Wiggenhauser Lucas M, Morgenstern Jakob, Fleming Thomas H, Poschet Gernot, B\u00fcttner Michael, Tabler Christoph T, Wohlfart David P, Nawroth Peter P, Kroll Jens", "evidence": [ { "database": "UniProtKB", "id": "B0S7W5", "url": "https://www.uniprot.org/uniprotkb/B0S7W5" } ], "reference": [ { "type": "PubMed", "id": "31217350", "url": "https://glygen.org/publication/PubMed/31217350" } ] }, { "title": "Elevated 4-hydroxynonenal induces hyperglycaemia via Aldh3a1 loss in zebrafish and associates with diabetes progression in humans.", "journal": "Redox Biol.", "date": "2020", "authors": "Lou Bowen, Boger Mike, Bennewitz Katrin, Sticht Carsten, Kopf Stefan, Morgenstern Jakob, Fleming Thomas, Hell R\u00fcdiger, Yuan Zuyi, Nawroth Peter Paul, Kroll Jens", "evidence": [ { "database": "UniProtKB", "id": "B0S7W5", "url": "https://www.uniprot.org/uniprotkb/B0S7W5" } ], "reference": [ { "type": "PubMed", "id": "32980661", "url": "https://glygen.org/publication/PubMed/32980661" } ] }, { "title": "Aldh2 is a lineage-specific metabolic gatekeeper in melanocyte stem cells.", "journal": "Development", "date": "2022", "authors": "Brunsdon Hannah, Brombin Alessandro, Peterson Samuel, Postlethwait John H, Patton E Elizabeth", "evidence": [ { "database": "UniProtKB", "id": "B0S7W5", "url": "https://www.uniprot.org/uniprotkb/B0S7W5" } ], "reference": [ { "type": "PubMed", "id": "35485397", "url": "https://glygen.org/publication/PubMed/35485397" } ] }, { "title": "ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma.", "journal": "Cell Rep.", "date": "2024", "authors": "Lu Yuting, Travnickova Jana, Badonyi Mihaly, Rambow Florian, Coates Andrea, Khan Zaid, Marques Jair, Murphy Laura C, Garcia-Martinez Pablo, Marais Richard, Louphrasitthiphol Pakavarin, Chan Alex H Y, Schofield Christopher J, von Kriegsheim Alex, Marsh Joseph A, Pavet Valeria, Sansom Owen J, Illingworth Robert S, Patton E Elizabeth", "evidence": [ { "database": "UniProtKB", "id": "B0S7W5", "url": "https://www.uniprot.org/uniprotkb/B0S7W5" } ], "reference": [ { "type": "PubMed", "id": "38963759", "url": "https://glygen.org/publication/PubMed/38963759" } ] } ], "pathway": [ { "id": "dre:100006238", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100006238", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P49189-1", "protein_name": "4-trimethylaminobutyraldehyde dehydrogenase", "gene_name": "ALDH9A1", 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"https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-507#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7ZVB2-1", "protein_name": "4-trimethylaminobutyraldehyde dehydrogenase A", "gene_name": "aldh9a1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAQQPLLSLPEFQSVSTGTLVVKEPLNFWGGARVKPRDTKNSEPVYEPATGRVLCDMIPCGEEEVDQAIKSAHSAYLKWSQLSGMERSRIMLEAARIIRERRNAIAKAEVANNGKSITEAEVDIDVAWQCIEYYAGIAPTLSGQHIQLPGGSFAYTRREPLGVCVGIGAWNYPFQIAAWKSAPALACGNAMVFKPSPMTPVTAVMLAEIYKEAGVPDGLFNVVQGGAETGSLLCHHPMVAKVSFTGSVPTGKKVMEMAAKSVKQVTLELGGKSPLIIFKDCELENAIKGALMANFLTQGEVCCNGTRVFVQREIMPKFLEEVVKRTKAISVGDPLCEGTRMGALISKPHMEKVLGFIKQAKEQGGKVLCGGERFVPNDPKLKDGYFVSPCVLDNCRDDMTCVKEEIFGPVMSVLPFDTEEEVLQRANNTTFGLASGVFTRDIARAHRVAANLQAGTCYINNYNVGPVEVPFGGYKMSGFGRENGTVTIEYYSQLKTVVVEMGDVESLF", "length": 508 }, "evidence": [ { "id": "RGD:68409", "url": "https://alliancegenome.org/gene/RGD:68409#orthology", "database": "AGR" }, { "id": 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"evidence": [ { "id": "RGD:68409", "url": "https://alliancegenome.org/gene/RGD:68409#orthology", "database": "AGR" }, { "id": "MGI:1861622", "url": "https://alliancegenome.org/gene/MGI:1861622#orthology", "database": "AGR" }, { "id": "HGNC:412", "url": "https://alliancegenome.org/gene/HGNC:412#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q9JLJ2-1", "protein_name": "4-trimethylaminobutyraldehyde dehydrogenase", "gene_name": "Aldh9a1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSTGTFVVSQPLNYRGGARVEPVDASGTEKAFEPATGRVIATFACSGEKEVNLAVENAKAAFKLWSKKSGLERCQVLLEAARIIKERKDEIATVETINNGKSIFEARLDVDTCWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCVGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLAEIYTKAGAPPGLFNVVQGGAATGQFLCHHREVAKISFTGSVPTGVKIMEMSAKGVKPITLELGGKSPLIIFSDCNMENAVKGALMANFLTQGQVCCNGTRVFVQKEIADKFINEVVKQTQKIKLGDPLLEDTRMGPLINAPHLERVLGFVKLAKEQGATVLCGGEVYVPEDPKLKHGYYMTPCILTNCRDDMTCVKEEIFGPVMSILTFGTEAEVLERANDTTFGLAAGVFTRDIQRAHRVAAELQAGTCYINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF", "length": 494 }, "evidence": [ { "id": "RGD:68409", "url": "https://alliancegenome.org/gene/RGD:68409#orthology", "database": "AGR" }, { "id": "MGI:1861622", "url": "https://alliancegenome.org/gene/MGI:1861622#orthology", "database": "AGR" }, { "id": "HGNC:412", "url": "https://alliancegenome.org/gene/HGNC:412#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-507", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-507#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JLJ3-1", "protein_name": "4-trimethylaminobutyraldehyde dehydrogenase", "gene_name": "Aldh9a1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSTGTFVVSQPLNYRGGARVEPVDASGTEKAFEPATGREIATFKCSGEKEVNLAVENAKAAFKIWSKKSGLERCQVLLEAARIIKERRDEIAIMETINNGKSIFEARLDVDTSWQCLEYYAGLAASMAGEHIQLPGGSFGYTRREPLGVCLGIGAWNYPFQIACWKSAPALACGNAMIFKPSPFTPVSALLLAEIYTKAGAPNGLFNVVQGGAATGQFLCQHRDVAKVSFTGSVPTGMKIMEMAAKGIKPITLELGGKSPLIIFSDCNMKNAVKGALLANFLTQGQVCCNGTRVFVQKEIADAFTKEVVRQTQRIKIGDPLLEDTRMGPLINAPHLERVLGFVRSAKEQGATVLCGGEPYAPEDPKLKHGYYMTPCILTNCTDDMTCVKEEIFGPVMSILTFETEAEVLERANDTTFGLAAGVFTRDIQRAHRVAAELQAGTCYINNYNVSPVELPFGGYKKSGFGRENGRVTIEYYSQLKTVCVEMGDVESAF", "length": 494 }, "evidence": [ { "id": "RGD:68409", "url": "https://alliancegenome.org/gene/RGD:68409#orthology", "database": "AGR" }, { "id": "MGI:1861622", "url": "https://alliancegenome.org/gene/MGI:1861622#orthology", "database": "AGR" }, { "id": "HGNC:412", "url": "https://alliancegenome.org/gene/HGNC:412#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-507", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-507#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "B0S7W5", "url": "https://www.uniprot.org/uniprotkb/B0S7W5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "aldehyde dehydrogenase (NAD+) activity", "id": "GO:0004029", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004029", "evidence": [ { "database": "UniProtKB", "id": "B0S7W5", "url": "https://www.uniprot.org/uniprotkb/B0S7W5" } ], "pmid": "" }, { "name": "4-trimethylammoniobutyraldehyde dehydrogenase activity", "id": "GO:0047105", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0047105", "evidence": [ { "database": "UniProtKB", "id": "B0S7W5", "url": "https://www.uniprot.org/uniprotkb/B0S7W5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" }, { "start_pos": 427, "end_pos": 429, "annotation": "n_glycosylation_sequon" }, { "start_pos": 428, "end_pos": 430, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "16185", "name": "", "equation": "an aldehyde + NAD(+) + H2O = a carboxylate + NADH + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "E9QH31-1", "Q7ZVB2-1", "Q802W2-1", "A0A8M1PLI9-1" ], "evidence": [ { "id": "16185", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/16185" } ] }, { "id": "17985", "name": "", "equation": "4-(trimethylamino)butanal + NAD(+) + H2O = 4-(trimethylamino)butanoate + NADH + 2 H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "Q7ZVB2-1", "Q802W2-1" ], "evidence": [ { "id": "17985", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/17985" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "A0A8M1PLI9", "gene_name": "aldh7a1", "activity": [ { "ec_number": "1.2.1.3", "activity": "acetaldehyde + NAD(+) + H2O = acetate + NADH + 2 H(+).", "evidence": [ { "id": "A0A8M1PLI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PLI9" } ] }, { "ec_number": "1.2.1.31", "activity": "(S)-2-amino-6-oxohexanoate + NAD(+) + H2O = L-2-aminoadipate + NADH + 2 H(+).", "evidence": [ { "id": "A0A8M1PLI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PLI9" } ] }, { "ec_number": "1.2.1.8", "activity": "betaine aldehyde + NAD(+) + H2O = glycine betaine + NADH + 2 H(+).", "evidence": [ { "id": "A0A8M1PLI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PLI9" } ] }, { "ec_number": "1.2.1.31", "activity": "", "evidence": [ { "id": "A0A8M1PLI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PLI9" } ] }, { "ec_number": "1.2.1.8", "activity": "", "evidence": [ { "id": "A0A8M1PLI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PLI9" } ] }, { "ec_number": "1.2.1.3", "activity": "", "evidence": [ { "id": "A0A8M1PLI9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PLI9" } ] } ] }, { "uniprot_ac": "E9QH31", "gene_name": "aldh3a2b", "activity": [ { "ec_number": "1.2.1.3", "activity": "acetaldehyde + NAD(+) + H2O = acetate + NADH + 2 H(+).", "evidence": [ { "id": "E9QH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ] }, { "ec_number": "1.2.1.94", "activity": "(2E,6E)-farnesal + NAD(+) + H2O = (2E,6E)-farnesoate + NADH + 2 H(+).", "evidence": [ { "id": "E9QH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ] }, { "ec_number": "1.2.1.94", "activity": "", "evidence": [ { "id": "E9QH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ] }, { "ec_number": "1.2.1.3", "activity": "", "evidence": [ { "id": "E9QH31", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QH31" } ] } ] }, { "uniprot_ac": "Q7ZVB2", "gene_name": "aldh9a1a", "activity": [ { "ec_number": "1.2.1.3", "activity": "acetaldehyde + NAD(+) + H2O = acetate + NADH + 2 H(+).", "evidence": [ { "id": "Q7ZVB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7ZVB2" } ] }, { "ec_number": "1.2.1.47", "activity": "4-(trimethylamino)butanal + NAD(+) + H2O = 4-(trimethylamino)butanoate + NADH + 2 H(+).", "evidence": [ { "id": "Q7ZVB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/Q7ZVB2" } ] }, { 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"name": "tstd1", "type": "synonym", "evidence": [ { "id": "XP_021328471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328471" } ] } ], "protein_names": [ { "name": "Thiosulfate:glutathione sulfurtransferase", "type": "synonym", "evidence": [ { "id": "B8A5G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5G0/entry#names_and_taxonomy" } ] }, { "name": "thiosulfate:glutathione sulfurtransferase", "type": "synonym", "evidence": [ { "id": "XP_021328471", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328471" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021328471", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328471" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A5G0", "url": "https://www.uniprot.org/uniprotkb/B8A5G0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tstd1", "url": "https://www.uniprot.org/uniprotkb/B8A5G0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081107-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081107-63", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "563265", "url": "https://www.ncbi.nlm.nih.gov/gene/563265", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:563265", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563265", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR45544", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45544", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45544:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45544:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021328471", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021328471", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8A5G0", "url": "https://www.uniprot.org/uniprotkb/B8A5G0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A5G0-1", "url": "https://www.uniprot.org/uniprotkb/B8A5G0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081107-63", "url": "https://zfin.org/ZDB-GENE-081107-63", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASSDNDISYSDLKSILAKGSAVLVDVRTNEEVARGTIPGSIHIPVGNIGQDLSLDAAEFQSKFGVGKPPLDCTELVFFCQLGRRGAAATEKAKSLGFKNARNYAGAYKEWSEKEGK", "length": 117, "header": "tr|B8A5G0-1|B8A5G0_DANRE Isoform 1 of Thiosulfate:glutathione sulfurtransferase OS=Danio rerio OX=7955 GN=tstd1 PE=1 SV=1 CANONICAL=B8A5G0-1" }, "isoforms": [ { "isoform_ac": "B8A5G0-1", "url": "https://www.uniprot.org/uniprotkb/B8A5G0/entry#B8A5G0-1", "sequence": { "sequence": "MASSDNDISYSDLKSILAKGSAVLVDVRTNEEVARGTIPGSIHIPVGNIGQDLSLDAAEFQSKFGVGKPPLDCTELVFFCQLGRRGAAATEKAKSLGFKNARNYAGAYKEWSEKEGK", "length": 117, "header": "tr|B8A5G0-1|B8A5G0_DANRE Isoform 1 of Thiosulfate:glutathione sulfurtransferase OS=Danio rerio OX=7955 GN=tstd1 PE=1 SV=1 CANONICAL=B8A5G0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "G49108TO", "type": "O-linked", "subtype": "O-GlcNAcylation", "prediction_tool_list": [], "site_category": "reported_with_glycan", "site_category_dict": { "reported_with_glycan": true }, "site_seq": "", "relation": "attached", "comment": "O-GlcNAcylation", "icn3d_view": {}, "evidence": [ { "id": "40044042", "database": "PubMed", "url": "https://glygen.org/publication/PubMed/40044042" }, { "id": "B8A5G0", "database": "O-GlcNAc Database", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=B8A5G0" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_reported_with_glycan" ], "publication": [ { "title": "Upregulation of Protein O-GlcNAcylation Levels Promotes Zebrafish Fin Regeneration.", "journal": "Molecular & cellular proteomics : MCP", "date": "2025-04", "authors": "Jia Liyuan, Zheng Hanxue, Feng Juantao, Ding Yi, Sun Xiaotian, Yu Yuan, Hao Xue, Wang Junxiang, Zhang Xinyu, Tian Yuanfeng, Chen Fulin, Cui Jihong", "evidence": [ { "database": "O-GlcNAc Database", "id": "B8A5G0", "url": "https://www.oglcnac.mcw.edu/search/?query_protein=B8A5G0" } ], "reference": [ { "type": "PubMed", "id": "40044042", "url": "https://glygen.org/publication/PubMed/40044042" } ] } ], "pathway": [ { "id": "dre:563265", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563265", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PUV1-1", "protein_name": "Thiosulfate:glutathione sulfurtransferase isoform X1", "gene_name": "si:ch211-161h7.8", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVSFQILRRLGVFALTKPVCHGRILSACGIKTSNINHSHGQPGAVSVVTYEQLKGMLANHSVQLFDVRNPDEFQAGRIPDSVNVPLGELEVSLKLPAEKFEEQFKVKAPQKADDNIVFHCRSGKRSLTALETAHRLGFSKARHYAGGYIDWEEREKN", "length": 157 }, "evidence": [ { "id": "FB:FBgn0038080", "url": "https://alliancegenome.org/gene/FB:FBgn0038080#orthology", "database": "AGR" }, { "id": "FB:FBgn0001228", "url": "https://alliancegenome.org/gene/FB:FBgn0001228#orthology", "database": "AGR" }, { "id": "SGD:S000005811", "url": "https://alliancegenome.org/gene/SGD:S000005811#orthology", "database": "AGR" }, { "id": "SGD:S000005812", "url": "https://alliancegenome.org/gene/SGD:S000005812#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LEJ3-1", "protein_name": "Rhodanese domain-containing protein", "gene_name": "Tstd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEVPENPWDVRVRCLQVPWGGLFVERGAWGVAAGLKQPGRGVQRQVSCPPALKSFFSFPVPTVSFSELRQLLASGRARLFDVRSREEAAAGTIPGALNIPVSELEMALNMDPAAFQTSYCAEKPKLEDKNLIFFCQMGRRGLQATQLAQGLGYTGARNYAGAYKEWLEKEG", "length": 171 }, "evidence": [ { "id": "MGI:3648482", "url": "https://alliancegenome.org/gene/MGI:3648482#orthology", "database": "AGR" }, { "id": "HGNC:35410", "url": "https://alliancegenome.org/gene/HGNC:35410#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081107-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081107-63#orthology", "database": "AGR" }, { "id": "FB:FBgn0038080", "url": "https://alliancegenome.org/gene/FB:FBgn0038080#orthology", "database": "AGR" }, { "id": "FB:FBgn0001228", "url": "https://alliancegenome.org/gene/FB:FBgn0001228#orthology", "database": "AGR" }, { "id": "RGD:2323815", "url": "https://alliancegenome.org/gene/RGD:2323815#orthology", "database": "AGR" }, { "id": "SGD:S000005811", "url": "https://alliancegenome.org/gene/SGD:S000005811#orthology", "database": "AGR" }, { "id": "SGD:S000005812", "url": "https://alliancegenome.org/gene/SGD:S000005812#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PY03-1", "protein_name": "Thiosulfate sulfurtransferase (rhodanese)-like domain containing 1", "gene_name": "Tstd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRLAVLRHSHTSAAAGTMAGVPTVSFSELRSLVASGRARLFDVRSPEEAAAGTIPGALNIPVSELEIALNMDPAAFQTLYCAEKPKLEDKNLIFFCQMGRRGLQATQLAQGLGYTGARNYAGAYKEWLEKQG", "length": 133 }, "evidence": [ { "id": "MGI:3648482", "url": "https://alliancegenome.org/gene/MGI:3648482#orthology", "database": "AGR" }, { "id": "HGNC:35410", "url": "https://alliancegenome.org/gene/HGNC:35410#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081107-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081107-63#orthology", "database": "AGR" }, { "id": "FB:FBgn0038080", "url": "https://alliancegenome.org/gene/FB:FBgn0038080#orthology", "database": "AGR" }, { "id": "FB:FBgn0001228", "url": "https://alliancegenome.org/gene/FB:FBgn0001228#orthology", "database": "AGR" }, { "id": "RGD:2323815", "url": "https://alliancegenome.org/gene/RGD:2323815#orthology", "database": "AGR" }, { "id": "SGD:S000005811", "url": "https://alliancegenome.org/gene/SGD:S000005811#orthology", "database": "AGR" }, { "id": "SGD:S000005812", "url": "https://alliancegenome.org/gene/SGD:S000005812#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "G3V8W9-1", "protein_name": "Thiosulfate sulfurtransferase like domain containing 3", "gene_name": "Tstd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLARLVLGTSCRAVLGSVEPALGGLKSRWGSSQHFCSTLSKDVTYRELKNLLNSKDIMLIDVRNTWEILEHGKIPGSVNIPLDEVGEALQMNPREFKEKYGEEKPSKSDRLVFSCLAGVRSKKAMDTAISLGFNSAQHYIGGWTEWVTYEISEKKQS", "length": 157 }, "evidence": [ { "id": "FB:FBgn0038080", "url": "https://alliancegenome.org/gene/FB:FBgn0038080#orthology", "database": "AGR" }, { "id": "FB:FBgn0001228", "url": "https://alliancegenome.org/gene/FB:FBgn0001228#orthology", "database": "AGR" }, { "id": "SGD:S000005811", "url": "https://alliancegenome.org/gene/SGD:S000005811#orthology", "database": "AGR" }, { "id": "SGD:S000005812", "url": "https://alliancegenome.org/gene/SGD:S000005812#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "H0UI37-1", "protein_name": "Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "gene_name": "TSTD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIEKCGWSEGLTSIKGNCHNFYTAISKDVTYKELKNLLNSKNIMLIDVREIWEILEYQKIPESINVPLDEVGEALQMNPRDFKEKYNEVKPSKSDS", "length": 97 }, "evidence": [ { "id": "SGD:S000005811", "url": "https://alliancegenome.org/gene/SGD:S000005811#orthology", "database": "AGR" }, { "id": "SGD:S000005812", "url": "https://alliancegenome.org/gene/SGD:S000005812#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P22978-1", "protein_name": "Rhodanese domain-containing protein CG4456", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATYEQVKDVPNHPDVYLIDVRRKEELQQTGFIPASINIPLDELDKALNLDGSAFKNKYGRSKPEKQSPIIFTCRSGNRVLEAEKIAKSQGYSNVVIYKGSWNEWAQKEGL", "length": 111 }, "evidence": [ { "id": "MGI:3648482", "url": "https://alliancegenome.org/gene/MGI:3648482#orthology", "database": "AGR" }, { "id": "HGNC:35410", "url": "https://alliancegenome.org/gene/HGNC:35410#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081107-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081107-63#orthology", "database": "AGR" }, { "id": "FB:FBgn0001228", "url": "https://alliancegenome.org/gene/FB:FBgn0001228#orthology", "database": "AGR" }, { "id": "RGD:2323815", "url": "https://alliancegenome.org/gene/RGD:2323815#orthology", "database": "AGR" }, { "id": "SGD:S000005811", "url": "https://alliancegenome.org/gene/SGD:S000005811#orthology", "database": "AGR" }, { "id": "SGD:S000005812", "url": "https://alliancegenome.org/gene/SGD:S000005812#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q08742-1", "protein_name": "Thiosulfate sulfurtransferase RDL2, mitochondrial", "gene_name": "RDL2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFKHSTGILSRTVSARSPTLVLRTFTTKAPKIYTFDQVRNLVEHPNDKKLLVDVREPKEVKDYKMPTTINIPVNSAPGALGLPEKEFHKVFQFAKPPHDKELIFLCAKGVRAKTAEELARSYGYENTGIYPGSITEWLAKGGADVKPKK", "length": 149 }, "evidence": [ { "id": "MGI:3648482", "url": "https://alliancegenome.org/gene/MGI:3648482#orthology", "database": "AGR" }, { "id": "HGNC:35410", "url": "https://alliancegenome.org/gene/HGNC:35410#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081107-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081107-63#orthology", "database": "AGR" }, { "id": "FB:FBgn0038080", "url": "https://alliancegenome.org/gene/FB:FBgn0038080#orthology", "database": "AGR" }, { "id": "FB:FBgn0001228", "url": "https://alliancegenome.org/gene/FB:FBgn0001228#orthology", "database": "AGR" }, { "id": "RGD:2323815", "url": "https://alliancegenome.org/gene/RGD:2323815#orthology", "database": "AGR" }, { "id": "SGD:S000005812", "url": "https://alliancegenome.org/gene/SGD:S000005812#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q12305-1", "protein_name": "Thiosulfate:glutathione sulfurtransferase", "gene_name": "RDL1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MWKAVMNAWNGTESQSKNVSNIQSYSFEDMKRIVGKHDPNVVLVDVREPSEYSIVHIPASINVPYRSHPDAFALDPLEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSHGYSNTSLYPGSMNDWVSHGGDKLDL", "length": 139 }, "evidence": [ { "id": "MGI:3648482", "url": "https://alliancegenome.org/gene/MGI:3648482#orthology", "database": "AGR" }, { "id": "HGNC:35410", "url": "https://alliancegenome.org/gene/HGNC:35410#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081107-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081107-63#orthology", "database": "AGR" }, { "id": "FB:FBgn0038080", "url": "https://alliancegenome.org/gene/FB:FBgn0038080#orthology", "database": "AGR" }, { "id": "FB:FBgn0001228", "url": "https://alliancegenome.org/gene/FB:FBgn0001228#orthology", "database": "AGR" }, { "id": "RGD:2323815", "url": "https://alliancegenome.org/gene/RGD:2323815#orthology", "database": "AGR" }, { "id": "SGD:S000005811", "url": "https://alliancegenome.org/gene/SGD:S000005811#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8NFU3-1", "protein_name": "Thiosulfate:glutathione sulfurtransferase", "gene_name": "TSTD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGAPTVSLPELRSLLASGRARLFDVRSREEAAAGTIPGALNIPVSELESALQMEPAAFQALYSAEKPKLEDEHLVFFCQMGKRGLQATQLARSLGYTGARNYAGAYREWLEKES", "length": 115 }, "evidence": [ { "id": "MGI:3648482", "url": "https://alliancegenome.org/gene/MGI:3648482#orthology", "database": "AGR" }, { "id": "HGNC:35410", "url": "https://alliancegenome.org/gene/HGNC:35410#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081107-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081107-63#orthology", "database": "AGR" }, { "id": "FB:FBgn0038080", "url": "https://alliancegenome.org/gene/FB:FBgn0038080#orthology", "database": "AGR" }, { "id": "FB:FBgn0001228", "url": "https://alliancegenome.org/gene/FB:FBgn0001228#orthology", "database": "AGR" }, { "id": "RGD:2323815", "url": "https://alliancegenome.org/gene/RGD:2323815#orthology", "database": "AGR" }, { "id": "SGD:S000005811", "url": "https://alliancegenome.org/gene/SGD:S000005811#orthology", "database": "AGR" }, { "id": "SGD:S000005812", "url": "https://alliancegenome.org/gene/SGD:S000005812#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D0B5-1", "protein_name": "Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "gene_name": "Tstd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLARLVLGTSGRAALGSVEPALGGLKSIWRCSQAFCSTPKGVTYRELKSLLNSKDIMLIDVRNTLEILEQGKIPGSINIPLDEVGEALQMNPVDFKEKYCQVKPSKSDRLVFSCLAGVRSKKAMDTAISLGFNSAQHYAGGWKEWVTYEISEEKQES", "length": 157 }, "evidence": [ { "id": "FB:FBgn0038080", "url": "https://alliancegenome.org/gene/FB:FBgn0038080#orthology", "database": "AGR" }, { "id": "FB:FBgn0001228", "url": "https://alliancegenome.org/gene/FB:FBgn0001228#orthology", "database": "AGR" }, { "id": "SGD:S000005811", "url": "https://alliancegenome.org/gene/SGD:S000005811#orthology", "database": "AGR" }, { "id": "SGD:S000005812", "url": "https://alliancegenome.org/gene/SGD:S000005812#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VCD9-1", "protein_name": "Rhodanese domain-containing protein", "gene_name": "BcDNA:RE30346", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMMRHCMMALRVARSQIPFSTARNTQSNLLQRFYSQAPQIGIVDYDVVKKLPSEPQKLLIDVREPEELKETGQIPASINIPLGVVSQELAASEQLFKSKYGREKPKPETEIIFHCKIGKRSLKAAEAAAALGFKNVKNYQGSWLDWAEREGLPK", "length": 154 }, "evidence": [ { "id": "HGNC:35410", "url": "https://alliancegenome.org/gene/HGNC:35410#orthology", "database": "AGR" }, { "id": "SGD:S000005811", "url": "https://alliancegenome.org/gene/SGD:S000005811#orthology", "database": "AGR" }, { "id": "SGD:S000005812", "url": "https://alliancegenome.org/gene/SGD:S000005812#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG33-1", "protein_name": "Sulfurtransferase", "gene_name": "Tst1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATYEEVKDIPNHPEKYLFDVRNESELKETGVLPASINIPLSELEKALNLPEEDFAQTYGRVKPAVDAVLIFSCKAGGRAARAANLASTLGFTNAKAYAGSWTEWQAKQS", "length": 110 }, "evidence": [ { "id": "MGI:3648482", "url": "https://alliancegenome.org/gene/MGI:3648482#orthology", "database": "AGR" }, { "id": "HGNC:35410", "url": "https://alliancegenome.org/gene/HGNC:35410#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081107-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081107-63#orthology", "database": "AGR" }, { "id": "FB:FBgn0038080", "url": "https://alliancegenome.org/gene/FB:FBgn0038080#orthology", "database": "AGR" }, { "id": "RGD:2323815", "url": "https://alliancegenome.org/gene/RGD:2323815#orthology", "database": "AGR" }, { "id": "SGD:S000005811", "url": "https://alliancegenome.org/gene/SGD:S000005811#orthology", "database": "AGR" }, { "id": "SGD:S000005812", "url": "https://alliancegenome.org/gene/SGD:S000005812#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "thiosulfate-thiol sulfurtransferase activity", "id": "GO:0050337", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050337", "evidence": [ { "database": "UniProtKB", "id": "B8A5G0", "url": "https://www.uniprot.org/uniprotkb/B8A5G0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sulfide oxidation, using sulfide:quinone oxidoreductase", "id": "GO:0070221", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070221", "evidence": [ { "database": "UniProtKB", "id": "B8A5G0", "url": "https://www.uniprot.org/uniprotkb/B8A5G0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8A5G0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5G0" }, { "id": "PS50206", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50206" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rhodanese", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 116, "start_aa": "Ala", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { 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"XP_021335626", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021335626", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EZT8", "url": "https://www.uniprot.org/uniprotkb/E7EZT8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZT8-1", "url": "https://www.uniprot.org/uniprotkb/E7EZT8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-3152", "url": "https://zfin.org/ZDB-GENE-030131-3152", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNSISFKYLRRECVYSRYCCVPFCKISSRFNSVISFHKLPLDRATRKMWLHNIRRKTFEVSPHVRVCSRHFTNDDFIEPSYPTARRLLKKGAVPTLFRWNNDSTSGQKRFRLWEKKASSSSDQEEELVPMDFQHEDHNYYCTSRVQNDEVVDPTDDLRNEVEVLKRKVAEFSVNQRFCLGRFAASDDDIRFYTRFATYNHLMAFWRIIQPASHNMFRVTRARADTTKCDVQATDKASVQFLLPIDEFFLFMVHLSVGLTKRDLAHRFNVHQSTVSQIISTWANFLYTILGSVHIWMSKEAVKAQMPKEFQDYPDTQVIIDCIELCCRIQSSDLFPDEGYDCTFKGLIGMAPHGAVTFVSSLYAGSVSDNEVLKKSGIVLYLKPEMAIMVNKDFLVDDSILCTVYRPAYPVKRELMEADEDVGKMGDTQSIAQLRVHIEHLICRVKQHKLLDSVMPFTSTRTINRLYIVACLFINYQDGPLLKRWT", "length": 485, "header": "tr|E7EZT8-1|E7EZT8_DANRE Isoform 1 of Uncharacterized protein si:ch211-262i1.5 OS=Danio rerio OX=7955 GN=si:ch211-262i1.5 PE=4 SV=1 CANONICAL=E7EZT8-1" }, "isoforms": [ { "isoform_ac": "E7EZT8-1", "url": "https://www.uniprot.org/uniprotkb/E7EZT8/entry#E7EZT8-1", "sequence": { "sequence": "MNSISFKYLRRECVYSRYCCVPFCKISSRFNSVISFHKLPLDRATRKMWLHNIRRKTFEVSPHVRVCSRHFTNDDFIEPSYPTARRLLKKGAVPTLFRWNNDSTSGQKRFRLWEKKASSSSDQEEELVPMDFQHEDHNYYCTSRVQNDEVVDPTDDLRNEVEVLKRKVAEFSVNQRFCLGRFAASDDDIRFYTRFATYNHLMAFWRIIQPASHNMFRVTRARADTTKCDVQATDKASVQFLLPIDEFFLFMVHLSVGLTKRDLAHRFNVHQSTVSQIISTWANFLYTILGSVHIWMSKEAVKAQMPKEFQDYPDTQVIIDCIELCCRIQSSDLFPDEGYDCTFKGLIGMAPHGAVTFVSSLYAGSVSDNEVLKKSGIVLYLKPEMAIMVNKDFLVDDSILCTVYRPAYPVKRELMEADEDVGKMGDTQSIAQLRVHIEHLICRVKQHKLLDSVMPFTSTRTINRLYIVACLFINYQDGPLLKRWT", "length": 485, "header": "tr|E7EZT8-1|E7EZT8_DANRE Isoform 1 of Uncharacterized protein si:ch211-262i1.5 OS=Danio rerio OX=7955 GN=si:ch211-262i1.5 PE=4 SV=1 CANONICAL=E7EZT8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:567573", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567573", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E7EZT8", "url": "https://www.uniprot.org/uniprotkb/E7EZT8" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7EZT8", "url": "https://www.uniprot.org/uniprotkb/E7EZT8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 101, "end_pos": 103, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EZT8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZT8" }, { "id": "PS50950", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50950" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "THAP-type", "eco_id": "ECO_0000259", "start_pos": 15, "end_pos": 97, "start_aa": "Tyr", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 101, "end_pos": 103 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FDX7-1", "uniprot_ac": "E7FDX7", "uniprot_id": "E7FDX7_DANRE", "mass": { "chemical_mass": 73868.0, "monoisotopic_mass": 73868.0 }, "refseq": { "ac": "XP_695200", "name": "E3 ubiquitin-protein ligase RNF38", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695200" }, "gene_names": [ { "name": "rnf38", "type": "recommended", "evidence": [ { "id": "E7FDX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FDX7" } ] }, { "name": "rnf38", "type": "synonym", "evidence": [ { "id": "XP_695200", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695200" } ] } ], "protein_names": [ { "name": "E3 ubiquitin-protein ligase RNF38", "type": "synonym", "evidence": [ { "id": "XP_695200", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695200" }, { "id": "E7FDX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FDX7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_695200.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_695200", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695200" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FDX7", "url": "https://www.uniprot.org/uniprotkb/E7FDX7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rnf38", "url": "https://www.uniprot.org/uniprotkb/E7FDX7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-8693", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8693", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000062055", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000062055", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd16679", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16679", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "566820", "url": "https://www.ncbi.nlm.nih.gov/gene/566820", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566820", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566820", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IRPWESA", "url": "https://omabrowser.org/oma/group/IRPWESA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7FDX7", "url": "https://www.orthodb.org/?gene=E7FDX7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46171:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46171:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13639", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13639", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_695200", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_695200", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7FDX7", "url": "https://www.uniprot.org/uniprotkb/E7FDX7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FDX7-1", "url": "https://www.uniprot.org/uniprotkb/E7FDX7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-8693", "url": "https://zfin.org/ZDB-GENE-030131-8693", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPIATTGHSASREPRVCSPDPVPKRADLCEDAGAQPAEYGGLEGGHSLGSTRLSGALESSSAASFSPPTSPFLLHHHHHHHHHHPHPVTMEPPRTRSRSRSGFYHGGLSNPNGNSGSGGGALSPAGGINHHHLHHHHQQQQQFGAHGHTENLRPPGSMLSPGAHRHAGPGVHRNSGAGAMGGVYHYHSEHACADATDKTEDSPSPKRQRLSQQSVLEFTSAPPSTPSPPIRPWELPPSRRPHPYPHPHYHPERCHTPARHRRSPPVRRQRGRRDRLSRHHPPHGSPGGGQDENYRHPPHPHSLHPYGQPPSHPPPGLDEPRAFHPPTLSPRLLHPPQQGAMVMDLHEQLPQGTVPVSYTVSPVPPHGLPAPLCTGQHLPACSSQQQVPACSVVFSGQQHYPICSVPPPMLPACSVQHLPVPYAFPSLLSSDPPFLLHPPHLSPHLPTPGQFLPFQAQQSRSPLQRIENEVELLGDHLSVGGGFNYPHSGHPSPLPPSTPLQFLSHEPLHQELFGMPYPHFMPRRITGRRYRSQQAVPPPPYHPSLLPYFLSVLPVQPTAVGPAISLELDVDDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPSNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVQRDSE", "length": 673, "header": "tr|E7FDX7-1|E7FDX7_DANRE Isoform 1 of E3 ubiquitin-protein ligase RNF38 OS=Danio rerio OX=7955 GN=rnf38 PE=4 SV=1 CANONICAL=E7FDX7-1" }, "isoforms": [ { "isoform_ac": "E7FDX7-1", "url": "https://www.uniprot.org/uniprotkb/E7FDX7/entry#E7FDX7-1", "sequence": { "sequence": "MPIATTGHSASREPRVCSPDPVPKRADLCEDAGAQPAEYGGLEGGHSLGSTRLSGALESSSAASFSPPTSPFLLHHHHHHHHHHPHPVTMEPPRTRSRSRSGFYHGGLSNPNGNSGSGGGALSPAGGINHHHLHHHHQQQQQFGAHGHTENLRPPGSMLSPGAHRHAGPGVHRNSGAGAMGGVYHYHSEHACADATDKTEDSPSPKRQRLSQQSVLEFTSAPPSTPSPPIRPWELPPSRRPHPYPHPHYHPERCHTPARHRRSPPVRRQRGRRDRLSRHHPPHGSPGGGQDENYRHPPHPHSLHPYGQPPSHPPPGLDEPRAFHPPTLSPRLLHPPQQGAMVMDLHEQLPQGTVPVSYTVSPVPPHGLPAPLCTGQHLPACSSQQQVPACSVVFSGQQHYPICSVPPPMLPACSVQHLPVPYAFPSLLSSDPPFLLHPPHLSPHLPTPGQFLPFQAQQSRSPLQRIENEVELLGDHLSVGGGFNYPHSGHPSPLPPSTPLQFLSHEPLHQELFGMPYPHFMPRRITGRRYRSQQAVPPPPYHPSLLPYFLSVLPVQPTAVGPAISLELDVDDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPSNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVQRDSE", "length": 673, "header": "tr|E7FDX7-1|E7FDX7_DANRE Isoform 1 of E3 ubiquitin-protein ligase RNF38 OS=Danio rerio OX=7955 GN=rnf38 PE=4 SV=1 CANONICAL=E7FDX7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 225, "start_aa": "Thr", "end_pos": 225, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr225", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] }, { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 447, "start_aa": "Thr", "end_pos": 447, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr447", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:566820", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566820", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZQX4-1", "protein_name": "Ring finger protein 38", "gene_name": "Rnf38", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVPRGRKRLDSASVGTRVPRARTIGDGGPGELAAGRASSHNRRRRPGPERWEQPRRAEPPLAGTGGDGRWLPREGGTGRGRLGAGGQRTADVSRQPGALCSRGSGEPARPCLDETQISPGANSAPLPGHPNKVICERVRLPSLFPLLPSDQDTTIQEDAHFKAFFQSEDSPSPKRQRLSHSVFDYTSASPAPSPPMRPWEMTSNRQPPSVRPNQHHFSGERCNTPARNRRSPPVRRQRGRRERLSRHNSISQDENYHHLPYAQQQAIEEPRAFHPPNVSPRLLHPAAHPPQQNAVMVDIHDQLHQGTVPVSYTVTTVAPHGIPLCTGQHIPACSTQQVPGCSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLLHPPHLSPHHPPHLPPPGQFVPFQTQQSRSPLQRIENEVELLGEHLQVGSFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPVPPPTYHPSLLPYVLSMLPVPPTVGPTFSFELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPSNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKGNRTCPICRADASEVHRDSE", "length": 627 }, "evidence": [ { "id": "HGNC:18052", "url": "https://alliancegenome.org/gene/HGNC:18052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-8693", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8693#orthology", "database": "AGR" }, { "id": "MGI:1920719", "url": "https://alliancegenome.org/gene/MGI:1920719#orthology", "database": "AGR" }, { "id": "RGD:621856", "url": "https://alliancegenome.org/gene/RGD:621856#orthology", "database": "AGR" }, { "id": "FB:FBgn0037705", "url": "https://alliancegenome.org/gene/FB:FBgn0037705#orthology", "database": "AGR" }, { "id": "E7FDX7", "url": "https://omabrowser.org/oma/group/E7FDX7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q08CG8-1", "protein_name": "RING finger protein 44", "gene_name": "rnf44", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MRPWEVAVSRRPTTAPLNQRRLVGEPCITPLHLRRSPPVRHQWGQRDRPALHTSLHQDENFHHAVFSQHQQVPLDESRQYSHSGAAPRMLHTANQPPQQSSIMVDLHEQMHQGSVPISYTVTTVTTHGFPIHTGQPIPACNAQQLPACSVMFSGQLSLLCCLPPPLIQACTMQHLPVSYQAFPPLISSEHFILHPSPAVAPHQPPPHPPHPPPPHLPPINQFVPIQPQHPRMPLQRVENEVDLRGDQHPLGTFSYPPAHHPPALTPSVPLQYLPQETLHQELPYPVPYPHMLPRRITGQRYRLQQPLPPPPPPPPYYPGFLPYFLSMLPVPPTAVGPAISLDLDVDDVEMENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNLENHQSEQTLCVVCFSDFESRQLLRVLPCNHEFHAKCVDKWLKTNRTCPICRADASEVHRDVE", "length": 448 }, "evidence": [ { "id": "FB:FBgn0037705", "url": "https://alliancegenome.org/gene/FB:FBgn0037705#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3UHJ8-1", "protein_name": "RING finger protein 44", "gene_name": "Rnf44", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRPWTLAVTKWPPSAPVGHWRVSTRLSSSPGQLWGRPSNLSVEEHRASAPAGRSPRMLHPATQQSPFMVDLHEQVHQGPVPLSYTVTTVTTQGFPLPTSQHIPGCSAQQLPACSVMFSGQHYPLCCLPPPQLIQACTMQQLPGPYHTYPHLISSDHYILHPPPPAPPPQPTHMAPLGQFVSLQTQHPRMPLQRLDNEMDLRGDQHPLGSFTYSTSATGPALSPSVPLHYLPHDPLHQELSFGVPYSHMMPRRLSTQRYRLQQPLPPPPPPPPPSYYPSFLPYFLSMLPMSPTTVGPTISLDLDVDDVEMENYEALLNLAERLGDAKPRGLTKADIEQLPSYRFNPDSHQSEQTLCVVCFSDFEVRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVPREAE", "length": 407 }, "evidence": [ { "id": "FB:FBgn0037705", "url": "https://alliancegenome.org/gene/FB:FBgn0037705#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4V7B8-1", "protein_name": "RING finger protein 44", "gene_name": "Rnf44", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLHPATQQSPFMVDLHDQVHQGPVPLSYTVTTVTTQGFPLPASQHIPGCSAQQLPACSVMFSGQHYPLCCLPPPLIQACTMQQLPVPYHTYPHLISSDHYILHPPPPAPPPQPTHMAPLGQFVSLQTQHPRMPLQRLDNEMDLRGDQHPLGSFTYSTSATGPTLSPSVPLHYLPHDPLHQELSFGVPYSHMMPRRLSTQRYRLQQPLPPPPPPPPPSYYPSFLPYFLSMLPMSPTTVGPTISLDLDVDDVEMENYEALLNLAERLGDAKPRGLTKADIEQLPSYRFNPDSHQSEQTLCVVCFSDFEVRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVPREAE", "length": 350 }, "evidence": [ { "id": "FB:FBgn0037705", "url": "https://alliancegenome.org/gene/FB:FBgn0037705#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7L0R7-1", "protein_name": "RING finger protein 44", "gene_name": "RNF44", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRPWALAVTRWPPSAPVGQRRFSAGPGSTPGQLWGSPGLEGPLASPPARDERLPSQQPPSRPPHLPVEERRASAPAGGSPRMLHPATQQSPFMVDLHEQVHQGPVPLSYTVTTVTTQGFPLPTGQHIPGCSAQQLPACSVMFSGQHYPLCCLPPPLIQACTMQQLPVPYQAYPHLISSDHYILHPPPPAPPPQPTHMAPLGQFVSLQTQHPRMPLQRLDNDVDLRGDQPSLGSFTYSTSAPGPALSPSVPLHYLPHDPLHQELSFGVPYSHMMPRRLSTQRYRLQQPLPPPPPPPPPPPYYPSFLPYFLSMLPMSPTAMGPTISLDLDVDDVEMENYEALLNLAERLGDAKPRGLTKADIEQLPSYRFNPDSHQSEQTLCVVCFSDFEARQLLRVLPCNHEFHTKCVDKWLKANRTCPICRADASEVPREAE", "length": 432 }, "evidence": [ { "id": "FB:FBgn0037705", "url": "https://alliancegenome.org/gene/FB:FBgn0037705#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BI21-1", "protein_name": "E3 ubiquitin-protein ligase RNF38", "gene_name": "Rnf38", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRESEDSPSPKRQRLSHSVFDYTSASPAPSPPMRPWEMTSNRQPPSVRPNQHHFSGERCNTPARNRRSPPVRRQRGRRERLSRHNSISQDENYHHLPYAQQQAIEEPRAFHPPNVSPRLLHPAAHPPQQNAVMVDIHDQLHQGTVPVSYTVTTVAPHGLPLCTGQHIPACSTQQVPGCSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLIHPPHLSPHHPPHLPPPGQFVPFQTQQSRSPLQRIENEVELLGEHLQVGSFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPMPPPPYHPSLLPYVLSMLPVPPAVGPTFSFELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPSNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKGNRTCPICRADASEVHRDSE", "length": 464 }, "evidence": [ { "id": "HGNC:18052", "url": "https://alliancegenome.org/gene/HGNC:18052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-8693", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8693#orthology", "database": "AGR" }, { "id": "MGI:1920719", "url": "https://alliancegenome.org/gene/MGI:1920719#orthology", "database": "AGR" }, { "id": "RGD:621856", "url": "https://alliancegenome.org/gene/RGD:621856#orthology", "database": "AGR" }, { "id": "FB:FBgn0037705", "url": "https://alliancegenome.org/gene/FB:FBgn0037705#orthology", "database": "AGR" }, { "id": "E7FDX7", "url": "https://omabrowser.org/oma/group/E7FDX7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H0F5-1", "protein_name": "E3 ubiquitin-protein ligase RNF38", "gene_name": "RNF38", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACKISPGANSASLPGHPNKVICERVRLQSLFPLLPSDQNTTVQEDAHFKAFFQSEDSPSPKRQRLSHSVFDYTSASPAPSPPMRPWEMTSNRQPPSVRPSQHHFSGERCNTPARNRRSPPVRRQRGRRDRLSRHNSISQDENYHHLPYAQQQAIEEPRAFHPPNVSPRLLHPAAHPPQQNAVMVDIHDQLHQGTVPVSYTVTTVAPHGIPLCTGQHIPACSTQQVPGCSVVFSGQHLPVCSVPPPMLQACSVQHLPVPYAAFPPLISSDPFLIHPPHLSPHHPPHLPPPGQFVPFQTQQSRSPLQRIENEVELLGEHLPVGGFTYPPSAHPPTLPPSAPLQFLTHDPLHQEVSFGVPYPPFMPRRLTGRSRYRSQQPIPPPPYHPSLLPYVLSMLPVPPAVGPTFSFELDVEDGEVENYEALLNLAERLGEAKPRGLTKADIEQLPSYRFNPNNHQSEQTLCVVCMCDFESRQLLRVLPCNHEFHAKCVDKWLKANRTCPICRADASEVHRDSE", "length": 515 }, "evidence": [ { "id": "HGNC:18052", "url": "https://alliancegenome.org/gene/HGNC:18052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-8693", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8693#orthology", "database": "AGR" }, { "id": "MGI:1920719", "url": "https://alliancegenome.org/gene/MGI:1920719#orthology", "database": "AGR" }, { "id": "RGD:621856", "url": "https://alliancegenome.org/gene/RGD:621856#orthology", "database": "AGR" }, { "id": "FB:FBgn0037705", "url": "https://alliancegenome.org/gene/FB:FBgn0037705#orthology", "database": "AGR" }, { "id": "E7FDX7", "url": "https://omabrowser.org/oma/group/E7FDX7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VHC2-1", "protein_name": "Murashka, isoform C", "gene_name": "mura", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLNSNATGGNNHGGSSRRPFTRNSSSVRSQRGGGGGLGGRMVYSPHTHPHVQQQQQQQQQQQQQGQQRSSNNGNNNLWLGNSPWCNVNLNGGNSGNNNNNGGNNNNNNGGNISSNNNSNNVNNKDANPNCDVQTSNSSGTCIYNNSKAHHHHNNSNNNGHTQSHIHTNHSLHQGHHHPHHTQMHTPHYPHSSSPQQSNSYRQYPPHSYSPNSPHSNGHTNSNASNNPISQRSNPQAHPNQNQNSNFYEMCTGSGGSHTYGSMSVSLVRLNPARLCLTLGPVTPPAQRVVSFGHRSHSHSNSSSNTSSSDQNQHNPPPRSQNHHPNPHHSQYQYQYQYQYRYQYHPPHQYHPLHSPQQQTNRQSLPLTRTNSNSINATTFNSTNPTTNSNPTDVVNVNSCTDIIPYGSSSTSSSASSMLPQQQQHQINNASAPINSHSQGQGPGNSPNLGHNHQRGYNNGNNNRGIGNGIVNGNTNGPPDYMNYRRGVCPAQSRDYSGNGNGNNNGHGHNGRRYMSDNLNNPSSSMNGLINSGHHQRNYNDRNLNNHFGNSEQNGGPDHRDRAEGSSYNFMRNGGGSGGGGYGRNGSHYQHMAYGNNNGASTSTGGPGLMGELPSGSGLSGSSLSLNNGPGGLNSDSPSRKRRRISGRPPNGPQPQHRCPMAHMQQGSPPLRRPRLRDVATSTQQQQQQYGHQVHHPQQQQQQPPSNYHPMHHHQPQPHYVPQQQVPPPHVQRSPWDLGSSGGSSGGATSSSSVGPILQQVQAPPQPPSHQQAVGYPQAPPQPASLMVDLNLNQVPVNLQLRPSEPFWASFCTYPIPAQARLAPCHLHGVYTQPFPAAPPPGLAAPPLQQQHQPLIQAQQMISQATLTAQQQQRDVVAIATANLGPIEAPGAHGHPHAHPHAHPHAHQLPPGIHITPLSGAAAAAATHHLHSTAAAAAAVAAGAQITTAQQILFSSDRRTFPPHRRIPRFWTANHGHRHVLPPQSLAAHQAPVQIQATSGIINPGFLLNFLAMFPLSPYNQHDLSSGDTNETENYEALLSLAERLGEAKPRGLTRNEIDQLPSYKFNPEVHNGDQSSCVVCMCDFELRQLLRVLPCSHEFHAKCVDKWLRSNRTCPICRGNASDYFDGVDQQQQSQATAGAAAALSGTSGGSAGVAGTSEASAATANPQQSQAA", "length": 1173 }, "evidence": [ { "id": "HGNC:18052", "url": "https://alliancegenome.org/gene/HGNC:18052#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-8693", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-8693#orthology", "database": "AGR" }, { "id": "MGI:1920719", "url": "https://alliancegenome.org/gene/MGI:1920719#orthology", "database": "AGR" }, { "id": "RGD:621856", "url": "https://alliancegenome.org/gene/RGD:621856#orthology", "database": "AGR" }, { "id": "FB:FBgn0037705", "url": "https://alliancegenome.org/gene/FB:FBgn0037705#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7FDX7", "url": "https://www.uniprot.org/uniprotkb/E7FDX7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 655, "end_pos": 657, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FDX7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FDX7" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 621, "end_pos": 662, "start_aa": "Cys", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 225, 447 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 655, "end_pos": 657 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 2 }, { "field": "total_sites", "count": 2 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 2 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 2 }, { "field": "exact_o_linked_sites", "count": 2 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F5G1-1", "uniprot_ac": "E7F5G1", "uniprot_id": "E7F5G1_DANRE", "mass": { "chemical_mass": 77462.0, "monoisotopic_mass": 77462.0 }, "refseq": { "ac": "XP_002660426", "name": "IQ domain-containing protein E isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660426" }, "gene_names": [ { "name": "iqce", "type": "recommended", "evidence": [ { "id": "E7F5G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5G1" } ] }, { "name": "iqce", "type": "synonym", "evidence": [ { "id": "XP_002660426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660426" } ] }, { "name": "si:dkey-21j8.2", "type": "synonym", "evidence": [ { "id": "XP_002660426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660426" }, { "id": "E7F5G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5G1" } ] } ], "protein_names": [ { "name": "IQ domain-containing protein E isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002660426", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660426" }, { "id": "E7F5G1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5G1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_002660426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660426" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F5G1", "url": "https://www.uniprot.org/uniprotkb/E7F5G1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "iqce", "url": "https://www.uniprot.org/uniprotkb/E7F5G1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090312-217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-217", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000089930", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000089930", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "323898", "url": "https://www.ncbi.nlm.nih.gov/gene/323898", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR052318", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052318", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:323898", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:323898", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TLISKCQ", "url": "https://omabrowser.org/oma/group/TLISKCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A0R4IP00", "url": "https://www.orthodb.org/?gene=A0A0R4IP00", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F5G1", "url": "https://www.orthodb.org/?gene=E7F5G1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22590", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22590", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22590:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22590:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_002660426", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660426", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A0R4IP00", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IP00", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A0R4IP00-1", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IP00-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F5G1", "url": "https://www.uniprot.org/uniprotkb/E7F5G1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F5G1-1", "url": "https://www.uniprot.org/uniprotkb/E7F5G1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090312-217", "url": "https://zfin.org/ZDB-GENE-090312-217", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSVVAGELGTEEEVEDLAEDSLCSSYVSDTEKQPRKKKVSGRPPPSPKSPYLNSANLHMKRAPAASCRTMKGLQLQNCKTPPAAPHRDVWLHLQDDGHGSLSKSPKVMDCSVTQSSISSARTPEYLKEALGMKKPKYSRSASNGYVPGTPDYKDKEEMYDEIIDLKKTIQTQKAESDKLRAKLRRFEEENCKKDRQIEQLLDPAKDPEYARSLVDRKTDPRSIINGLKQRILRLEQQCKEKENALSQLQSDHKTTNMQEMKITVETYFEEVQRLRTLLDSAERSNKAESKESRRQNKTLSTTVLRLTKTVQQLEEENQELKKELTQEEMSMTDSPACRAKGYMDWSKQRLVRRILELEKRLERMKNLQITKASQKSLDDTESTNQNAETEPSMITENDVLLNGVVTKLGEQKSELKLKLTQRDEEIRRLSAEKDERLKEVENVLKEQIRNHESLIQTHRQEMSALIVEITCLKEKLEEERNLKVVQDPIQVRDSSSLSTEPSSPSDFGTKKKNKAAEIIQKHWRSHRKRDLVLLQSCLRGHLIRQRHLEGQKQADLGTVPASMSQSGKSTQAVQEEEVTLLQSVFRAHLKRSTMNTDRAQSVSSIHQNKQHVLPAGSSQAVFTSKTQSSGVKIHQQEPATEIPKSVDSDDSDDIIVSPSRPPRKKEQPFSCFPFSADDLI", "length": 680, "header": "tr|E7F5G1-1|E7F5G1_DANRE Isoform 1 of IQ domain-containing protein E isoform X1 OS=Danio rerio OX=7955 GN=iqce PE=4 SV=1 CANONICAL=E7F5G1-1" }, "isoforms": [ { "isoform_ac": "A0A0R4IP00-1", "url": "https://www.uniprot.org/uniprotkb/E7F5G1/entry#A0A0R4IP00-1", "sequence": { "sequence": "MSVVAGELGTEEEVEDLAEDSLCSSYVSDTEKPRKKKVSGRPPPSPKSPYLNSANLHMKRAPAASCRTMKGLQLQNCKTPPAAPHRDVWLHLQDDGHGSLSKSPKVMDCSVTQSSISSARTPEYLKEALGMKKPKYSRSASNGYVPGTPDYKDKEEMYDEIIDLKKTIQTQKAESDKLRAKLRRFEEENCKKDRQIEQLLDPAKDPEYARSLVDRKTDPRSIINGLKQRILRLEQQCKEKENALSQLQSDHKTTNMQEMKITVETYFEEVQRLRTLLDSAERSNKAESKESRRQNKTLSTTVLRLTKTVQQLEEENQELKKELTQEEMSMTDSPACRAKGYMDWSKQRLVRRILELEKRLERMKNLQITKASQKSLDDTESTNQNAETEPSMITENDVLLNGVVTKLGEQKSELKLKLTQRDEEIRRLSAEKDERLKEVENVLKEQIRNHESLIQTHRQEMSALIVEITCLKEKLEEERNLKVVQDPIQVRDSSSLSTEPSSPSDFGTKKKNKAAEIIQKHWRSHRKRDLVLLQSCLRGHLIRQRHLEGQKQADLGTVPASMSQSGKSTQAVQEEEVTLLQSVFRAHLKRSTMNTDRAQSVSSIHQNKQHVLPAGSSQAVFTSKTQSSGVKIHQQEPATEIPKSVDSDDSDDIIVSPSRPPRKKEQPFSCFPFSADDLI", "length": 679, "header": "tr|A0A0R4IP00-1|E7F5G1_DANRE Computationally mapped isoform of IQ domain-containing protein E isoform X1 OS=Danio rerio OX=7955 GN=iqce PE=4 SV=1 CANONICAL=E7F5G1-1" }, "locus": {} }, { "isoform_ac": "E7F5G1-1", "url": "https://www.uniprot.org/uniprotkb/E7F5G1/entry#E7F5G1-1", "sequence": { "sequence": "MSVVAGELGTEEEVEDLAEDSLCSSYVSDTEKQPRKKKVSGRPPPSPKSPYLNSANLHMKRAPAASCRTMKGLQLQNCKTPPAAPHRDVWLHLQDDGHGSLSKSPKVMDCSVTQSSISSARTPEYLKEALGMKKPKYSRSASNGYVPGTPDYKDKEEMYDEIIDLKKTIQTQKAESDKLRAKLRRFEEENCKKDRQIEQLLDPAKDPEYARSLVDRKTDPRSIINGLKQRILRLEQQCKEKENALSQLQSDHKTTNMQEMKITVETYFEEVQRLRTLLDSAERSNKAESKESRRQNKTLSTTVLRLTKTVQQLEEENQELKKELTQEEMSMTDSPACRAKGYMDWSKQRLVRRILELEKRLERMKNLQITKASQKSLDDTESTNQNAETEPSMITENDVLLNGVVTKLGEQKSELKLKLTQRDEEIRRLSAEKDERLKEVENVLKEQIRNHESLIQTHRQEMSALIVEITCLKEKLEEERNLKVVQDPIQVRDSSSLSTEPSSPSDFGTKKKNKAAEIIQKHWRSHRKRDLVLLQSCLRGHLIRQRHLEGQKQADLGTVPASMSQSGKSTQAVQEEEVTLLQSVFRAHLKRSTMNTDRAQSVSSIHQNKQHVLPAGSSQAVFTSKTQSSGVKIHQQEPATEIPKSVDSDDSDDIIVSPSRPPRKKEQPFSCFPFSADDLI", "length": 680, "header": "tr|E7F5G1-1|E7F5G1_DANRE Isoform 1 of IQ domain-containing protein E isoform X1 OS=Danio rerio OX=7955 GN=iqce PE=4 SV=1 CANONICAL=E7F5G1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain.", "journal": "PLoS ONE", "date": "2008", "authors": "Sreenivasan Rajini, Cai Minnie, Bartfai Richard, Wang Xingang, Christoffels Alan, Orban Laszlo", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IP00", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IP00" } ], "reference": [ { "type": "PubMed", "id": "18335061", "url": "https://glygen.org/publication/PubMed/18335061" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IP00", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IP00" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Novel IQCE variations confirm its role in postaxial polydactyly and cause ciliary defect phenotype in zebrafish.", "journal": "Hum. Mutat.", "date": "2020", "authors": "Estrada-Cuzcano A, Etard C, Delvallee C, Stoetzel C, Schaefer E, Scheidecker S, Geoffroy V, Schneider A, Studer F, Mattioli F, Chennen K, Sigaudy S, Plassard D, Poch O, Piton A, Strahle U, Muller J, Dollfus H", "evidence": [ { "database": "UniProtKB", "id": "A0A0R4IP00", "url": "https://www.uniprot.org/uniprotkb/A0A0R4IP00" } ], "reference": [ { "type": "PubMed", "id": "31549751", "url": "https://glygen.org/publication/PubMed/31549751" } ] } ], "pathway": [ { "id": "dre:323898", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:323898", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0AAA9TAL9-1", "protein_name": "IQ motif containing E", "gene_name": "IQCE", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSQGTAEPASETGDDSLSAITFDSDSDTKAKKKSFHKPPPTSLKSPYHSKPRKVASWRSLRTAASMPLGGRMSLTPQKLCLGSSKQGSLTPALTSDLTLDCAWTHSPSSAPDFVTEALRMKRSNLRRSASHGYVPGNPVYREKEDMYDEIIELKKSLNMQKSDVDLMRTKLRRLEEENSRKDRQIEQLLDASRGPDFVRTLAEKRPDAGWVINGLKQRVLKLEQQCKEKDNIINKLQTDVKTTNLEEMRIAMETYYEEIHRLHGLLASSEMTGKRPPVEKKIGLKRQKKMSSALLSLSRSVQELTEENQSLKEDLDRMLSNSPTASKIKGYTDWSKPRLVRRIAELEKKLSSMESPKPQASEAARSTSLTPSASSPTLHLQENERLHGAVKSLKGERSALHTQLQERDLEVKQLLQTKAELEKELESMKEGERERREREKALREEVQTLTRKFQELEGSKKDKEDEPVAAAPQTHEEPSQPPSPTASPSQPDAEPDWNQGGSSWPPSTCSEGRRDEAARVLQRRWKGYQRQKERALLDEAATVLQAAFRGHLARARLLSRAACVSEPPRVPSPPTQDSPEPRIPSPAAQAEGDPWQEEAVTIIQSAFRAHLARARHSDPGPGASTAAVPDRPAQPPPRAPCSPPCPVAGPGQGDSEGSSRETAKGPAPEDGAPRPPPCSEPPVSVLQPMAPTPAEDVNSDDSDEIVLAPSLPTRKSACLP", "length": 720 }, "evidence": [ { "id": "E7F5G1", "url": "https://omabrowser.org/oma/group/E7F5G1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0M2F5-1", "protein_name": "IQ domain-containing protein E", "gene_name": "Iqce", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDLYTSKKNPLRRNLVLRVVPYALSPESTQHGDPRNLCPLGYIVAATVCVNPTGAPEVGSESTAGSDIESQPCLREAIGSIRAPGETKNSHKRQGAIAQCNPGRVHGWPLARAHTARAQDSPGIGGRTTSGALWPRHGCHGTRLAGRPPKLRAELAGPPRPRSAAAMSLGTTDLTSETGDDSLSAISFDSDVESKTKRKPLHKPPSTSPKSPYYSKPKKVTSWRSLKTAGSMPLSSRMSLTPQKLWLGTSKQGHVSGTSVYREKEDMYDEIIELKKSLHMQKSDVDLMRTKLRRLEEENSRKDRQIEQLLDPGRGPDFVRTLAEKKPDTGWVITGLKQRIFRLEQQCKEKDSTINKLQTDMKTTNLEEMRIAMETYYEEIHRLQTLLASSEATGKKPILEKKMGVKRQKKMSSALLNLTRSVQELTEENQSLKEDLDRMLSNSPTVSKIKGYVDWSKPRLLRRIAELEKKVSSSESPKNSASELVKPNPVVPSPSNISVQKQLKGDQSKEDQPKVDPSEDQEHLQGTVKTLREELSALQEQLLGKDLEMKQMLQSKIDLEKELETAREGEKESQEREQALREEVEALTKKCQELEEAKRQETQERQDSFIAMTHEAHPEVHAPSPCSRHSEPDSDNNADNNAGEDGGSQPPALCSEERREAAIRTLQAQWKAHRCKKRKAALDEAATVLQAAFRGHLARSKLVPNKAPDSRSPSLPGLPSPLNQSSPSPPVPSPISPAEDSLTQEESIIVIQSILRGYLAQARVIANCCQEKTGPSQREAVSVTPSESASPPSLEASPGKDSEESGGEVAEDEDEAEEPPDPQPYSGALSMGLHAEEELRETAASEPAPSVPDSARGGQGDCPSSSSLEAVPCGKDAMCEERSSSTGSARPSLAEPSPPGLQPLSPPPVEDICSDDSDDIIFSPFLPRKKSPSPF", "length": 935 }, "evidence": [ { "id": "HGNC:29171", "url": "https://alliancegenome.org/gene/HGNC:29171#orthology", "database": "AGR" }, { "id": "MGI:1921489", "url": "https://alliancegenome.org/gene/MGI:1921489#orthology", "database": "AGR" }, { "id": "E7F5G1", "url": "https://omabrowser.org/oma/group/E7F5G1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6IPM2-1", "protein_name": "IQ domain-containing protein E", "gene_name": "IQCE", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFLGTGEPALDTGDDSLSAVTFDSDVETKAKRKAFHKPPPTSPKSPYLSKPRKVASWRSLRTAGSMPLGGRASLTPQKLWLGTAKPGSLTQALNSPLTWEHAWTGVPGGTPDCLTDTFRVKRPHLRRSASNGHVPGTPVYREKEDMYDEIIELKKSLHVQKSDVDLMRTKLRRLEEENSRKDRQIEQLLDPSRGTDFVRTLAEKRPDASWVINGLKQRILKLEQQCKEKDGTISKLQTDMKTTNLEEMRIAMETYYEEVHRLQTLLASSETTGKKPLGEKKTGAKRQKKMGSALLSLSRSVQELTEENQSLKEDLDRVLSTSPTISKTQGYVEWSKPRLLRRIVELEKKLSVMESSKSHAAEPVRSHPPACLASSSALHRQPRGDRNKDHERLRGAVRDLKEERTALQEQLLQRDLEVKQLLQAKADLEKELECAREGEEERREREEVLREEIQTLTSKLQELQEMKKEEKEDCPEVPHKAQELPAPTPSSRHCEQDWPPDSSEEGLPRPRSPCSDGRRDAAARVLQAQWKVYKHKKKKAVLDEAAVVLQAAFRGHLTRTKLLASKAHGSEPPSVPGLPDQSSPVPRVPSPIAQATGSPVQEEAIVIIQSALRAHLARARHSATGKRTTTAASTRRRSASATHGDASSPPFLAALPDPSPSGPQALAPLPGDDVNSDDSDDIVIAPSLPTKNFPV", "length": 695 }, "evidence": [ { "id": "HGNC:29171", "url": "https://alliancegenome.org/gene/HGNC:29171#orthology", "database": "AGR" }, { "id": "MGI:1921489", "url": "https://alliancegenome.org/gene/MGI:1921489#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-217#orthology", "database": "AGR" }, { "id": "E7F5G1", "url": "https://omabrowser.org/oma/group/E7F5G1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6PCQ0-1", "protein_name": "IQ domain-containing protein E", "gene_name": "Iqce", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLGTTDIASETGDDSLSAITFESDIESKTKRKSFHKPPSTSPKSPYYSKPRKVTSWRSLKTAGSMPLSSRMSLTPQKLWLGSSKQGSVAQPPSPTLTSEHAWTHPPSCTPDYLTEAVRAKRADLRRSGSHGHVSGTSVYREKEDMYDEIIELKKSLHMQKSDVDLMRTKLRRLEEENSRKDRQIEQLLDPSRGPDFVRTLAEKKPDTGWVITGLKQRIFRLEQQCKEKDNTINKLQTDMKTTNLEEMRIAMETYYEEIHRLQTLLASSEATGKKPMVEKKLGVKRQKKMSSALLNLTRSVQELTEENQSLKEDLDRMLSNSPTISKIKGYGDWSKPRLLRRIAELEKKVSSSESPKQSTSELVNPNPLVRSPSNISVQKQPKGDQSPEDLPKVAPCEEQEHLQGTVKSLREELGALQEQLLEKDLEMKQLLQSKIDLEKELETAREGEKGRQEQEQALREEVEALTKKCQELEEAKREEKNSFVAVTHEAHPELHAPSPCSRHSEPDSDNSAGEEGSSQPPAPCSEERREAAIRTLQAQWKAHRRKKREAALDEAATVLQAAFRGHLARSKLVRSKVPDSRSPSLPGLLSPLNQSSPAPRVLSPISPAEENPTQEEAVIVIQSILRGYLAQARFIASCCREIAASSQRETVSLTPSGSASPPSLRASPGVIRKELCASEELRETSASEPAPSVPYSAQGGHGDCPSSSSLEAVPSMKDAMCEERSSSPRSAGPSLAEPSPPELQPLSPPPVEDICSDDSDDIIFSPFLPRKKSPSPF", "length": 778 }, "evidence": [ { "id": "HGNC:29171", "url": "https://alliancegenome.org/gene/HGNC:29171#orthology", "database": "AGR" }, { "id": "MGI:1921489", "url": "https://alliancegenome.org/gene/MGI:1921489#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-217", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-217#orthology", "database": "AGR" }, { "id": "E7F5G1", "url": "https://omabrowser.org/oma/group/E7F5G1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 296, "end_pos": 298, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 296, "end_pos": 298 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1Q7J9-1", "uniprot_ac": "F1Q7J9", "uniprot_id": "F1Q7J9_DANRE", "mass": { "chemical_mass": 142822.0, "monoisotopic_mass": 142822.0 }, "refseq": { "ac": "XP_692034", "name": "TBC1 domain family member 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692034" }, "gene_names": [ { "name": "tbc1d9b", "type": "recommended", "evidence": [ { "id": "F1Q7J9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9" } ] }, { "name": "tbc1d9", "type": "recommended", "evidence": [ { "id": "F1Q7J9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9" } ] }, { "name": "tbc1d9", "type": "synonym", "evidence": [ { "id": "XP_692034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692034" } ] } ], "protein_names": [ { "name": "TBC1 domain family member 9", "type": "recommended", "evidence": [ { "id": "F1Q7J9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9/entry#names_and_taxonomy" } ] }, { "name": "TBC1 domain family member 9", "type": "synonym", "evidence": [ { "id": "XP_692034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692034" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_692034.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_692034", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692034" } ] }, { "annotation": "May act as a GTPase-activating protein for Rab family protein(s).", "evidence": [ { "database": "UniProtKB", "id": "E7F7E8", "url": "https://www.uniprot.org/uniprotkb/E7F7E8#function" }, { "database": "UniProtKB", "id": "ARBA00043879", "url": "https://www.uniprot.org/uniprotkb/ARBA00043879#function" }, { "database": "UniProtKB", "id": "F1Q7J9", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9#function" }, { "database": "UniProtKB", "id": "A0A286Y906", "url": "https://www.uniprot.org/uniprotkb/A0A286Y906#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q7J9", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tbc1d9", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060810-33", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-33", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ZFIN:ZDB-GENE-230815-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-230815-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000043627", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000043627", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "ENSDARG00000059900", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000059900", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13351", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13351", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13354", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13354", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100332046", "url": "https://www.ncbi.nlm.nih.gov/gene/100332046", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "563578", "url": "https://www.ncbi.nlm.nih.gov/gene/563578", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000195", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000195", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002048", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002048", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR004182", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004182", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011992", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011992", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035969", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035969", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036014", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036014", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036017", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036017", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:563578", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563578", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CTGEVPT", "url": "https://omabrowser.org/oma/group/CTGEVPT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "HMCFYAY", "url": "https://omabrowser.org/oma/group/HMCFYAY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A286Y906", "url": "https://www.orthodb.org/?gene=A0A286Y906", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F7E8", "url": "https://www.orthodb.org/?gene=E7F7E8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "F1Q7J9", "url": "https://www.orthodb.org/?gene=F1Q7J9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47666:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47666:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47666:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47666:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00566", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00566", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF02893", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02893", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_692034", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692034", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A286Y906", "url": "https://www.uniprot.org/uniprotkb/A0A286Y906", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A286Y906-1", "url": "https://www.uniprot.org/uniprotkb/A0A286Y906-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F7E8", "url": "https://www.uniprot.org/uniprotkb/E7F7E8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F7E8-1", "url": "https://www.uniprot.org/uniprotkb/E7F7E8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q7J9", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q7J9-1", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060810-33", "url": "https://zfin.org/ZDB-GENE-060810-33", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] }, { "id": "ZDB-GENE-230815-1", "url": "https://zfin.org/ZDB-GENE-230815-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MWVNPEEVLLASALWMTERANPYFVLQKRKGHGDGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIAHGSSRKEITENWEWLEQNLLQTLSIFENENDITTFVKGKIQGIIAEYNKSHDIKEDDDTDKFKEAIAKFRKLFVMPEEEKLVNYYSCSYWKGKVPRQGWLYLSINHICFYSYLLGKEVKLVVRWADVTQLEKSATLLLPDMVRVSTRCSEHVFSVFLNINETFKLMEQLANIAMRQLLDNKGFEQDRSLPKLKKKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEETVCSLIIPLREVTIVEKADSSNVLPSPLSISTKNKMTFLFANLKDRDFLVQRISDFLQQTTSKIYFEREITGSLSSSDDEVYSQQGSVLSCSPQRSALVSEGESERQFNLNDNRVPTATQALMTMYRRRSPEEFNPKLAKEFLKEQAWKNHFTEYGQGVCMYRTDKTKDLVLQGIPENMRGELWLLFSGAINEMATHPGYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVAMCERMLPDYYNTRVVGALVDQGVFEELAHVHVPQLYDCMQALGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALSVLDANIHQLLGCKDDGEAMTILGRYLDSVTNKDSTLPPIPHLHSLLTDNGEPHPEVDIFKLVRSSYEKFGSIRADVIEQMRFKQRLRVIQAIEDTTKRNVVRTIVTETPFSIDELEELYSLFKAEHLTSCYWGSSSNPMSRHDPSLPYLEQYRIDLEQFKGLFTLLFPWACGSHADDLAFRFFRLLDHNTDALINFREFISGLSVLCHGDLTEKLKFLYKIHILPELHHEQEEPDSACEATQYFFEDITPETSSGLDHKSRSEKDDGFVRVTFKNEKVKKTHTADYRTYLRLWNQETKAKLENMKDLPKLNQSQFIELCKTLYNMFSEDPNEQELYHATATVTSLLLEMGEVGKLFCTPASKHNNEDDDEEEDERSIPTCRNKQDRPHRKPCDITPPLDEIKLEDSSPKDTATSSAMLISDDETKDDTSMSSYSVLSAGSHELDDKLQCEDIADDTVLIRNGGAGHHGRSGLPHSASIDKDWAITFEQFLASVLTEQALVQYFEKPVDVAGRITNAKNVRKVGHQHMSVSDYEISLSG", "length": 1248, "header": "tr|F1Q7J9-1|F1Q7J9_DANRE Isoform 1 of TBC1 domain family member 9 OS=Danio rerio OX=7955 GN=tbc1d9 PE=4 SV=2 CANONICAL=F1Q7J9-1" }, "isoforms": [ { "isoform_ac": "A0A286Y906-1", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9/entry#A0A286Y906-1", "sequence": { "sequence": "MWITPEEVLLANALWVSERANPYFILQRRKGHGRGGGITGLLVGTLDVVLDSSARVAPYRILHQTGESQIFWNIACGSSRKEITEHWEWLEANLLQTLSIFDNDDDITTFVKGKIQGIIAEENKGGKPQEDEDPGKFREAELKMRKLFGMPEEEKLVNYYPCSYWKGRVPRQGWIYLSVNHLCFYSFLLGKEVSLVVQWTDVTQLDKNATLVFPESIRVSTRDTEHFFSMFLNINETFKLMEQLANIAMRQLLDNESFAADRSLPKPANKTLKNVSALKRDLDARAKNERYRALFRLTQDERLDGHTDCTLWTPFAKMHVVGQMFVSNNYICFTSREEDLCQLIIPLREVTIVEKADSSSVLPSPLSISTKNKMTFLFANLKDRDFLVQRISDFLQRTPDGPCGVLQSENPSPSTPPSPPVLSLSESAQMQHYSPSLPTARKGLLQIYQQDVPEELGPKVTRERMKEESWKIHFFEFGRGVCMYRTSKTRELVLNGIPESLRGELWLLFSGAQNEMATHPGYYGNLVEQAMGRCTLATEEIERDLHRSMPEHHAFQNETGIAALRRVLTAYAYRNPGIGYCQAMNIVTSVLLLYCTEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELTRECLPLLYEHMQDLGVISTISLSWFLTLFLSVMPFDSAVLLVDCFFYEGIKVIFQVSLAVLHANMDQLLSCSDEGEAMTILGRYLDNVVNKQTVSPPIPHLHALLTSGNNPPPEIDVFELIKASYEKFGSLRADVIEQMRFKQRLKVIQSLEDTAKRSVVRAIMTESAFTIEELEELYVLFKAKHIMSCYWGASSTPAERHDPSLPYLEQYRIDCGQFVQLFSALAPWSCGLHTHTLSSRLFRLLDHNKDSLINFKEFVTGLSGMYHGDMTEKLKLLYKLHLPPALCPEEAESALEATQFFTDDDTPQGEELKEAGDSAAAGDTDDRKEEKPKDYKYYLRMWAKEKEPKKKSIKDLPRMNQEQFIEMCKTLYNMFSEDPLEQELYHGIATVASLLLRIGEVGKKFTNNGSKKAEAPADASQPEKEDSSGEGGSGLSLVSKALAEAQMETPPPTANGSDEEAKDDTSVSSYSVVSAGSLQCEDIADDTVLIGCVGGEGAGRRRGSAPDADWSITFEQVLASFLTEASLVDYFEKKHDIQSKITACKSLRAVERQTSSSSDHDFSLNTH", "length": 1201, "header": "tr|A0A286Y906-1|F1Q7J9_DANRE Computationally mapped isoform of TBC1 domain family member 9 OS=Danio rerio OX=7955 GN=tbc1d9 PE=4 SV=2 CANONICAL=F1Q7J9-1" }, "locus": {} }, { "isoform_ac": "E7F7E8-1", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9/entry#E7F7E8-1", "sequence": { "sequence": "MWITPEEVLLANALWVSERANPYFILQRRKGHGRGGGITGLLVGTLDVVLDSSARVAPYRILHQTGESQIFWNIACGSSRKEITEHWEWLEANLLQTLSIFDNDDDITTFVKGKIQGIIAEENKGGKPQEDEDPGKFREAELKMRKLFGMPEEEKLVNYYPCSYWKGRVPRQGWIYLSVNHLCFYSFLLGKEVSLVVQWTDVTQLDKNATLVFPESIRVSTRDTEHFFSMFLNINETFKLMEQLANIAMRQLLDNESFAADRSLPKPANKTLKNVSALKRDLDARAKNERYRALFRLTQDERLDGHTDCTLWTPFAKMHVVGQMFVSNNYICFTSREEDLCQLIIPLREVTIVEKADSSSVLPSPLSISTKNKMTFLFANLKDRDFLVQRISDFLQRTPDGPCGVLQSENPSPSTPPSPPVLSLSESAQMQHYSPSLPTARKGLLQIYQQDVPEELGPKVTRERMKEESWKIHFFEFGRGVCMYRTSKTRELVLNGIPESLRGELWLLFSGAQNEMATHPGYYGNLVEQAMGRCTLATEEIERDLHRSMPEHHAFQNETGIAALRRVLTAYAYRNPGIGYCQAMNIVTSVLLLYCTEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELTRECLPLLYEHMQDLGVISTISLSWFLTLFLSVMPFDSAVLLVDCFFYEGIKVIFQVSLAVLHANMDQLLSCSDEGEAMTILGRYLDNVVNKQTVSPPIPHLHALLTSGNNPPPEIDVFELIKASYEKFGSLRADVIEQMRFKQRLKVIQSLEDTAKRSVVRAIMTESAFTIEELEELYVLFKAKHIMSCYWGASSTPAERHDPSLPYLEQYRIDCGQFVQLFSALAPWSCGLHTHTLSSRLFRLLDHNKDSLINFKEFVTGLSGMYHGDMTEKLKLLYKLHLPPALCPEEAESALEATQFFTDDDTPQDPPFLSHLDFLAQEVTSGEELKEAGDSAAAGDTDDRKEEKPKDYKYYLRMWAKEKEPKKKSIKDLPRMNQEQFIEMCKTLYNMFSEDPLEQELYHGIATVASLLLRIGEVGKKFTNNGSKKAEAPADASQPEKEDSSGEGGSGLSLVSKALAEAQMETPPPTANGSDEEAKDDTSVSSYSVVSAGSLQCEDIADDTVLIGCVGGEGAGRRRGSAPDADWSITFEQVLASFLTEASLVDYFEKKHDIQSKITACKSLRAVERQTSSSSDHDFSLNTH", "length": 1218, "header": "tr|E7F7E8-1|E7F7E8_DANRE Computationally mapped isoform of TBC1 domain family member 9B OS=Danio rerio OX=7955 GN=tbc1d9b PE=4 SV=2 CANONICAL=F1Q7J9-1" }, "locus": {} }, { "isoform_ac": "F1Q7J9-1", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9/entry#F1Q7J9-1", "sequence": { "sequence": "MWVNPEEVLLASALWMTERANPYFVLQKRKGHGDGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIAHGSSRKEITENWEWLEQNLLQTLSIFENENDITTFVKGKIQGIIAEYNKSHDIKEDDDTDKFKEAIAKFRKLFVMPEEEKLVNYYSCSYWKGKVPRQGWLYLSINHICFYSYLLGKEVKLVVRWADVTQLEKSATLLLPDMVRVSTRCSEHVFSVFLNINETFKLMEQLANIAMRQLLDNKGFEQDRSLPKLKKKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEETVCSLIIPLREVTIVEKADSSNVLPSPLSISTKNKMTFLFANLKDRDFLVQRISDFLQQTTSKIYFEREITGSLSSSDDEVYSQQGSVLSCSPQRSALVSEGESERQFNLNDNRVPTATQALMTMYRRRSPEEFNPKLAKEFLKEQAWKNHFTEYGQGVCMYRTDKTKDLVLQGIPENMRGELWLLFSGAINEMATHPGYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVAMCERMLPDYYNTRVVGALVDQGVFEELAHVHVPQLYDCMQALGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALSVLDANIHQLLGCKDDGEAMTILGRYLDSVTNKDSTLPPIPHLHSLLTDNGEPHPEVDIFKLVRSSYEKFGSIRADVIEQMRFKQRLRVIQAIEDTTKRNVVRTIVTETPFSIDELEELYSLFKAEHLTSCYWGSSSNPMSRHDPSLPYLEQYRIDLEQFKGLFTLLFPWACGSHADDLAFRFFRLLDHNTDALINFREFISGLSVLCHGDLTEKLKFLYKIHILPELHHEQEEPDSACEATQYFFEDITPETSSGLDHKSRSEKDDGFVRVTFKNEKVKKTHTADYRTYLRLWNQETKAKLENMKDLPKLNQSQFIELCKTLYNMFSEDPNEQELYHATATVTSLLLEMGEVGKLFCTPASKHNNEDDDEEEDERSIPTCRNKQDRPHRKPCDITPPLDEIKLEDSSPKDTATSSAMLISDDETKDDTSMSSYSVLSAGSHELDDKLQCEDIADDTVLIRNGGAGHHGRSGLPHSASIDKDWAITFEQFLASVLTEQALVQYFEKPVDVAGRITNAKNVRKVGHQHMSVSDYEISLSG", "length": 1248, "header": "tr|F1Q7J9-1|F1Q7J9_DANRE Isoform 1 of TBC1 domain family member 9 OS=Danio rerio OX=7955 GN=tbc1d9 PE=4 SV=2 CANONICAL=F1Q7J9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1105, "start_aa": "Thr", "end_pos": 1105, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1105", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:563578", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563578", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0YY71-1", "protein_name": "TBC1 domain family member 9B", "gene_name": "TBC1D9B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MWLGPEEVLLAGALWVTERANPFFLLQRRRGHGKGGGLTGLLVGTLDVVLDSSARVAPYRILHQTQDSQVYWAVACGSSRKEITKHWEWLENNLLQTLSIFDNEEDITTFVKGKIHGIIAEENKNQQPQSEEDPGKFKEAELKMRKQFGMPEVEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVTLVIQWVDVTQLEKNATLLFPECIKVRTRDSELYFSMFLNINETFKLMEQLANIAMRQLLDNESFLQDKSLPKPRKPLKNISALKRDLDARAKNECYRATFRLPKDECLDGHTDCTLWTPFNKMHIPGQMFVSNNYICFASKAEEACHLIIPLREVTIVEKADSSSVLPSPLSISTKSKMTFFFANLKDRDFLVQRISDFLQRTPSKKPISSEREWKWNLGDPGCEEVPELPSSSPLAVSPTSALNNRPVNFCAGEVPTASQGLLKLFRRNSEELLGPKGAKEKMKEESWNIHFFEYGRGMCMYRTTKTRELVQKGIPENLRGELWLLFSGAWNEMVTHPGYYADLVEKSMGKYNLATEEIERDLHRSMPEHPAFQNELGIAALRRVLTAYAFRNPTIGYCQAMNIVTSVLLLYCNEEEAFWLLVALCERMLPDYYNTRVVGALVDQGIFEELTREYLPQLSEKMQELGVISTISLSWFLTLFLSVMPFESAVVIVDCFFYEGIKFILQVSLAILDANVEKLLQCCDEGEAMTILGRYLDNVVNRQSVSPPIPHLHALLTSGDDPPLEIDIFDLIKTSYEKFSNLKVDDIEQMRFKQRLKVIQSLEDTAKKSVVRAVSSDIGFSIEELEELYVVFKAKYLMSCYWGNNRAAAARRDQSLPYLEQYRIDMEQFKELFITLTPWSCGAHTPVLAGRLFRLLDENRDSLINFKEFVTGMSGMYHGDLTEKLKVLYKLHLPPALNPEETESALEATSYFTEDVTTEVSPFVSELDFCLHCESQETQEEKGRRNDSGQEKEEKGTSPQDYRYYLRMWAKEKESKKETIKDLPKMSQEQFIELCKTLYNMFSEDPVEQELYHAIATVASLLLRIGEVGKKFSNRPIRKSEDCKTNSSQDPVSEEESPTSEQSQNSTVEQQPRADCEDKTCRDVQPEKTEQENQTLGDGSGEGQGSPLQLLSDDETKDDMSMSSYSMVSTGSLQCEDIADDTVLVGCEGGSSAARYGSTIDTDWSISFEQILASMLTETALVNYFEKKVNILQKIKDQKKVERQFSSSSDYELSSVSG", "length": 1254 }, "evidence": [ { "id": "F1Q7J9", "url": "https://omabrowser.org/oma/group/F1Q7J9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZXE3-1", "protein_name": "TBC1 domain family member 9", "gene_name": "Tbc1d9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWVNPEEVLLANALWITERANPYFILQRRKGHGGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEVTEHWEWLEQNLLQTLSIFENENDVTTFVRGKIQGIIAEYNKINDVKEDEDTEKFKEAIVKFHRLFGMPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFSSFLMGREAKLVIRWVDITQLEKNATLLLPDMIKVSTRSSEHFFSVFLNINETFKLMEQLANIAMRQLLDNEGFEQDRSLPKLKKKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVEKADSCSVLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSRIYSEFSGSCNSSDDEVYSRPSSLVSSSPQRSTSSDADGERPFNLNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPERMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLGCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVGPYPAVDIFRLIGTSYEKFGTIRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTIDELEELYALFKAEHLTSCYWGGSSNAPDRHDPSLPYLEQYRIDFEQFKGMFVLLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPSCDQDEPDSAFEATQYFFEDITPECTHVVGLDSRGKQSADEGFVTVSLKQDRGKRANSQENRHYLKLWTAENKSKSKNAKDLPKLNQGQFIELCKTMYNMFSEDPNEQELYHATAAVTSLLLEIGEVGKFFITQPAKEDAVPGPPCSQAIPGMLFPKKGSSQSYVVESTDPLPASLAGDREEHSLGGQMEDIKLEDSSPRDNGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDKLHCEDIGEDTVLVRSSQGRAALPRSSSLDRDWAITFEQFLASLLTEPALVRYFDKPVCMMTRVTSAKNIRMMGKPLTSASDYDISALSG", "length": 1262 }, "evidence": [ { "id": "MGI:1918560", "url": "https://alliancegenome.org/gene/MGI:1918560#orthology", "database": "AGR" }, { "id": "HGNC:21710", "url": "https://alliancegenome.org/gene/HGNC:21710#orthology", "database": "AGR" }, { "id": "F1Q7J9", "url": "https://omabrowser.org/oma/group/F1Q7J9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1LRL4-1", "protein_name": "TBC1 domain family member 9B", "gene_name": "Tbc1d9b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWLGPEEVLVANALWVTERANPFFVLQRRRGHGKGGGLTGLLVGTLDVVLDSSARVAPYRILHQTQDSQVYWTVACGSSRKEITKHWEWLENNLLQTLSIFDNEEDITTFVKGKIHGIIAEENKNLQPQGDEDPGKFKEAELKMRKQFGMPEGEKLVNYYSCSFWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSLVVQWVDVTRLEKNATLLFPESIRVDTRDQELFFSMFLNIGETFKLMEQLANLAMRQLLDSEGFLEDKALPRPIRPHKNISALKRDLDARAKNECYRATFRLPKDERLDGHTGCTLWTPFNKLHIPGQMFISYNYICFASKEEDACRLIIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDFLVQRISDFLQKTPSKQTGSIAGGTKASVPDPAPESLPTPQEASEPPTSPTSPLSSPLSFSTQEIPTTSQGLLKVFQKNSPMEDLGAKGAKEKMKEESWNIHFFEYGRGVCMYRTAKTRELVLKGIPESLRGELWLLFSGAWNEMVTHPGYYAELVEKSMGKYSLATEEIERDLHRSMPEHPAFQNELGIAALRRVLTAYAFRNPTIGYCQAMNIVTSVLLLYGSEEEAFWLLVALCERMLPDYYNTRVVGALVDQGIFEELTRDVLPRLSEKMQELGVISSISLSWFLTLFLSVMPFESAVVIVDCFFYEGIKVILQVALAVLDANMEQLLDCSDEGEAMTVLGRYLDNVVNKQSISPPIPHLHALLTSGDDPPAEVDIFDLLKVSYEKFSSLRADDIEQMRFKQRLKVIQSLEDTAKRSVVRAIPGDIGFSIEELEDLYMVFKAKHLASQYWGGNRSAAIHRDPSLPYLEQYRIDASQFRELFASLTPWACGSHTPVLAGRMFRLLDQNKDSLINFKEFVTGMSGMYHGDLTEKLKALYKLHLPPALIPEEAESALEAAHYFPEDSSSEASPLASDLDLFLPWEAQAGLQEQQEGRGSEDIQERREEKETSPPDYRHYLRIWAKEKEAQKETIKDLPKMNQEQFIELCKTLYNMFSEDPLEQDLYHAIATVASLLLRIGEVGKKFSALTTKKPRDGAHSGDHNSATEEDEPPISKLHQDPARECQPPAAGDPQAKASGDMHLGKALQDSHVIVEGGSGEGQGSPSLLLSDDETKDDMSMSSYSVVSTGSLPCEDLTEDTVLVGGEACSPTATSRMGGTVDMDWCISFEQILASILTESVLVNFFEKRVDIGLKIKDQKKVERQFSTSSDHEPPGVLG", "length": 1263 }, "evidence": [ { "id": "F1Q7J9", "url": "https://omabrowser.org/oma/group/F1Q7J9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MS95-1", "protein_name": "TBC1 domain family member 9", "gene_name": "TBC1D9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MWVNPEEVLLANALWITERANPYFILQRRKGHSGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEITEHWEWLEQNLLQTLSIFENENDITTFVRGKIQGIIAEYNKINDVKEDDDTEKFKEAIVKFHRLFGMPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFYSFLMGREAKLVIRWVDITQLEKNATLLLPDVIKVSTRSSEHFFSVFLNINETFKLMEQLANIAMRQLLDNEGFEQDRSLPKLKKKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVEKADSSSVLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSKIYSDKEFAGSYNSSDDEVYSRPSSLVSSSPQRSTSSDADGERQFNLNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGVCMYRTEKTRELVLKGVPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLNCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVEPYPEVDIFRLIRTSYEKFGTIRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTTDELEELYALFKAEHLTSCYWGGNSNALDRHDPSLPYLEQYRIDLEQFKGMFALLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPSSDQDEPDSAFEATQYFFEDITPECTHVVGLESRNKHSADDGFVTVSLKPDRGKRANSQENRSYLRLWTPENKSKAKNAKDLPKLNQGQFIELCKTMYNMFSEDPNEQELYHATAAVTSLLLEIGEVGKLFAPQPAKEGGGGGSGPAGHQGLPGSVLFPKKGPSQPYVPEAAEPLPASLAGASEEHSLGGQMEDIKLEDSSPRDHGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDKLHCEDIGEDTVLVRSGQGTAALPRSTSLDRDWAITFEQFLASLLTEPALVKYFDKPVCMMARITSAKNIRMMGKPLTSISDYEISALSG", "length": 1267 }, "evidence": [ { "id": "F1Q7J9", "url": "https://omabrowser.org/oma/group/F1Q7J9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P53258-1", "protein_name": "GTPase-activating protein GYP2", "gene_name": "MDR1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSFFDSLRQKAPFLDKLADSFTPTLTRDEKFRLKYKLPANENILEDTNAEVSFATSIKDGKGHSDRVNNKGRKTAYVYSGRLFLTPHFLVFRDAFDHSSCVLILNISTIKRVERSPSESYEFALLVTLYTGAKVLIQFIGIRYRSEQFCDKLKLNLKENIPNAKTLPAFLETSYSEFLIAKNILGKKDITVPRAGLGQHFKYPGNPTMVKEKAKLRLWFDYFRENGRNLAVVQTPMFRKLIRIGVPNRMRGEIWELCSGAMYMRYANSGEYERILNENAGKTSQAIDEIEKDLKRSLPEYSAYQTEEGIQRLRNVLTAYSWKNPDVGYCQAMNIVVAGFLIFMSEEQAFWCLCNLCDIYVPGYYSKTMYGTLLDQRVFESFVEDRMPVLWEYILQHDIQLSVVSLPWFLSLFFTSMPLEYAVRIMDIFFMNGSITLFQVALAVLKINADDILQADDDGMFIAIIKHYFQTLGQSAHPDSSDIKYRQITKFQELLVTAFKEFSVISEEMAMHARHKYEKGIFQNIETFMKRTQLRHMPKTFNLSSDDLSNIYDMFYQSIETYKISMGTGSSNMGFEVFIQFLSKFCDSCRPCEKDKDPAFRKQKRNFLQRLFDNWDSAHIGELTLNDVVTGLDKLVTVDLLQAINYFFSLYDTDGDGELHREEVLQLSEGLLLLTEPWKSGRYVDLLTKKRIEDDIAENIIKESGGEIATMNQIELPTGVTIDEEKYKVEQAERYLKAASNFLQRSFEYAKAVDLAEEVNLIDLSDDEGEEKRTVKQKQLESIKANAALDPTHPKVIDLPTFRMIILADETYELFFSNTLRSSVHVDEHVNIDNKNKVLRSMFDGILADGKRVAEQVRRRVDSVATRSSIASVESTPTAAASSITTKEEKYDDLDDFTSEHQPENEELLQSSWFEIDDANETSTKAIQERSFEPLSANSSEEKSNLIEFEA", "length": 950 }, "evidence": [ { "id": "MGI:1918560", "url": "https://alliancegenome.org/gene/MGI:1918560#orthology", "database": "AGR" }, { "id": "HGNC:21710", "url": "https://alliancegenome.org/gene/HGNC:21710#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q3UYK3-1", "protein_name": "TBC1 domain family member 9", "gene_name": "Tbc1d9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWVNPEEVLLANALWITERANPYFILQRRKGHGGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEVTEHWEWLEQNLLQTLSIFENENDVTTFVRGKIQGIIAEYNKINDVKEDEDTEKFKEAIVKFHRLFGMPEEEKLVNYYSCSYWKGRVPRQGWMYLSINHLCFSSFLMGREAKLVIRWVDITQLEKNATLLLPDMIKVSTRSSEHFFSVFLNINETFKLMEQLANIAMRQLLDNEGFEQDRSLPKLKKKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVEKADSCSVLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSRIYSDKEFSGSCNSSDDEVYSRPSSLVSSSPQRSTSSDADGERPFNLNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEGLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLNCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVGPYPAVDIFRLIGTSYEKFGTIRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTIDELEELYALFKAEHLTSCYWGGSSNALDRHDPSLPYLEQYRIDFEQFKGMFVLLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPSCDQDEPDSAFEATQYFFEDITPECTHVVGLDSRGKQSADDGFVTVSLKQDRGKRANSQENRNYLKLWTAENKSKSKTAKDLPKLNQGQFIELCKTMYNMFSEDPNEQELYHATAAVTSLLLEIGEVGKFFITQPAKEDAVPGPPCGQAIPGMLFPKKGSSQSYVVESTEPLTASLAVDSEEHSLGGQMEDIKLEDSSPRDNGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDKLHCEDIGEDTVLVRSSQGRATLPRSSSLDRDWAITFEQFLASLLTEPALVRYFDKPVCMMARVTSAKNIRMMGKPLTSASDYEISALSG", "length": 1264 }, "evidence": [ { "id": "MGI:1918560", "url": "https://alliancegenome.org/gene/MGI:1918560#orthology", "database": "AGR" }, { "id": "HGNC:21710", "url": "https://alliancegenome.org/gene/HGNC:21710#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060810-33", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-33#orthology", "database": "AGR" }, { "id": "F1Q7J9", "url": "https://omabrowser.org/oma/group/F1Q7J9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5SVR0-1", "protein_name": "TBC1 domain family member 9B", "gene_name": "Tbc1d9b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWLGPEEVLVANALWVTERANPFFVLQRRRGHGKGGGLTGLLVGTLDVVLDSSARVAPYRILHQTQDSQVYWIVACGSSRKEITKHWEWLENNLLQTLSIFDNEEDITTFVKGKIHGIIAEENKNLQPQGDEDPGKFKEAELKMRKQFGMPEGEKLVNYYSCNFWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSLVVQWVDVTRLEKNATLLFPESIRVDTRDQELFFSMFLNIGETFKLMEQLANLAMRQLLDSEGFLEDKALPRPIRPHKNISALKRDLDARAKNECYRATFRLPKDERLDGHTGCTLWTPFNKLHIPGQMFISNNYICFASKEEDACRLIIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDFLVQRISDFLQKTPSKQTGSSIGGTKASVSDPAPESLPTPQEASEPPASPSSPLSSPPSFSTQEIPTTSQGLLKVFQKNSPMEDLGAKGAKEKMKEESWNIHFFEYGRGMCMYRTAKTRELVLKGIPESLRGELWLLFSGAWNEMVTHPGYYAELVEKSLGKYSLATEEIERDLHRSMPEHPAFQNELGIAALRRVLTAYAFRNPTIGYCQAMNIVTSVLLLYGSEEEAFWLLVALCERMLPDYYNTRVVGALVDQGIFEELTRDVLPRLSEKMQELGVISSISLSWFLTLFLSVMPFESAVVIVDCFFYEGIKVILQVALAVLDANVEQLLDCNDEGEAMTVLGRYLDNVVNKQSISPPIPHLHALLTSGDDPPVEVDIFDLLRVSYEKFSNLRADDIEQMRFKQRLKVIQSLEDTAKRSVVRAIPGDIGFSIEELEDLYMVFKAKHLASQYWGGNRSAAVHRDPSLPYLEQYRIDASQFRELFASLTPWACGSHTPVLAGRMFRLLDQNKDSLINFKEFVTGMSGMYHGDLTEKLKALYKLHLPPALIPEEAESALEAAHYFTEDSSSEASPLASDLDLFLPWEAQALLQEQQEGSGNEDTPERREEKGTSPPDYRHYLRMWAKEKEAQKETIKDLPKMNQEQFIELCKTLYNMFSEDPMEQDLYHAIATVASLLLRIGEVGKKFSALTTKKPRDGAHSGDPNSATEEDEPPTPKLHQDPTQECQPPAAGDRQAKASGDMHLGKALQDSHVIVEGGSGEGQGSPSLLLSDDETKDDMSMSSYSVVSTGSLQCEDLTEDTVLVGGGACSPTATSRAGGTVDTDWCISFEQILASILTESVLVNFFEKRVDIGLKIKDQKKVERQFSTSSDHEPPGVLG", "length": 1263 }, "evidence": [ { "id": "F1Q7J9", "url": "https://omabrowser.org/oma/group/F1Q7J9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q66K14-1", "protein_name": "TBC1 domain family member 9B", "gene_name": "TBC1D9B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWLSPEEVLVANALWVTERANPFFVLQRRRGHGRGGGLTGLLVGTLDVVLDSSARVAPYRILHQTQDSQVYWTVACGSSRKEITKHWEWLENNLLQTLSIFDSEEDITTFVKGKIHGIIAEENKNLQPQGDEDPGKFKEAELKMRKQFGMPEGEKLVNYYSCSYWKGRVPRQGWLYLTVNHLCFYSFLLGKEVSLVVQWVDITRLEKNATLLFPESIRVDTRDQELFFSMFLNIGETFKLMEQLANLAMRQLLDSEGFLEDKALPRPIRPHRNISALKRDLDARAKNECYRATFRLPRDERLDGHTSCTLWTPFNKLHIPGQMFISNNYICFASKEEDACHLIIPLREVTIVEKADSSSVLPSPLSISTKSKMTFLFANLKDRDFLVQRISDFLQKTPSKQPGSIGSRKASVVDPSTESSPAPQEGSEQPASPASPLSSRQSFCAQEAPTASQGLLKLFQKNSPMEDLGAKGAKEKMKEESWHIHFFEYGRGVCMYRTAKTRALVLKGIPESLRGELWLLFSGAWNEMVTHPGYYAELVEKSTGKYSLATEEIERDLHRSMPEHPAFQNELGIAALRRVLTAYAFRNPTIGYCQAMNIVTSVLLLYGSEEEAFWLLVALCERMLPDYYNTRVVGALVDQGIFEELTRDFLPQLSEKMQDLGVISSISLSWFLTLFLSVMPFESAVVIVDCFFYEGIKVILQVALAVLDANMEQLLGCSDEGEAMTMLGRYLDNVVNKQSVSPPIPHLRALLSSSDDPPAEVDIFELLKVSYEKFSSLRAEDIEQMRFKQRLKVIQSLEDTAKRSVVRAIPVDIGFSIEELEDLYMVFKAKHLASQYWGCSRTMAGRRDPSLPYLEQYRIDASQFRELFASLTPWACGSHTPLLAGRMFRLLDENKDSLINFKEFVTGMSGMYHGDLTEKLKVLYKLHLPPALSPEEAESALEAAHYFTEDSSSEASPLASDLDLFLPWEAQEALPQEEQEGSGSEERGEEKGTSSPDYRHYLRMWAKEKEAQKETIKDLPKMNQEQFIELCKTLYNMFSEDPMEQDLYHAIATVASLLLRIGEVGKKFSARTGRKPRDCATEEDEPPAPELHQDAARELQPPAAGDPQAKAGGDTHLGKAPQESQVVVEGGSGEGQGSPSQLLSDDETKDDMSMSSYSVVSTGSLQCEDLADDTVLVGGEACSPTARIGGTVDTDWCISFEQILASILTESVLVNFFEKRVDIGLKIKDQKKVERQFSTASDHEQPGVSG", "length": 1250 }, "evidence": [ { "id": "F1Q7J9", "url": "https://omabrowser.org/oma/group/F1Q7J9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6ZT07-1", "protein_name": "TBC1 domain family member 9", "gene_name": "TBC1D9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWVNPEEVLLANALWITERANPYFILQRRKGHAGDGGGGGGLAGLLVGTLDVVLDSSARVAPYRILYQTPDSLVYWTIACGGSRKEITEHWEWLEQNLLQTLSIFENENDITTFVRGKIQGIIAEYNKINDVKEDDDTEKFKEAIVKFHRLFGMPEEEKLVNYYSCSYWKGKVPRQGWMYLSINHLCFYSFLMGREAKLVIRWVDITQLEKNATLLLPDVIKVSTRSSEHFFSVFLNINETFKLMEQLANIAMRQLLDNEGFEQDRSLPKLKRKSPKKVSALKRDLDARAKSERYRALFRLPKDEKLDGHTDCTLWTPFNKMHILGQMFVSTNYICFTSKEENLCSLIIPLREVTIVEKADSSSVLPSPLSISTRNRMTFLFANLKDRDFLVQRISDFLQQTTSKIYSDKEFAGSYNSSDDEVYSRPSSLVSSSPQRSTSSDADGERQFNLNGNSVPTATQTLMTMYRRRSPEEFNPKLAKEFLKEQAWKIHFAEYGQGICMYRTEKTRELVLKGIPESMRGELWLLLSGAINEKATHPGYYEDLVEKSMGKYNLATEEIERDLHRSLPEHPAFQNEMGIAALRRVLTAYAFRNPNIGYCQAMNIVTSVLLLYAKEEEAFWLLVALCERMLPDYYNTRVVGALVDQGVFEELARDYVPQLYDCMQDLGVISTISLSWFLTLFLSVMPFESAVVVVDCFFYEGIKVIFQLALAVLDANVDKLLNCKDDGEAMTVLGRYLDSVTNKDSTLPPIPHLHSLLSDDVEPYPEVDIFRLIRTSYEKFGTIRADLIEQMRFKQRLKVIQTLEDTTKRNVVRTIVTETSFTIDELEELYALFKAEHLTSCYWGGSSNALDRHDPSLPYLEQYRIDFEQFKGMFALLFPWACGTHSDVLASRLFQLLDENGDSLINFREFVSGLSAACHGDLTEKLKLLYKMHVLPEPSSDQDEPDSAFEATQYFFEDITPECTHVVGLDSRSKQGADDGFVTVSLKPDKGKRANSQENRNYLRLWTPENKSKSKNAKDLPKLNQGQFIELCKTMYNMFSEDPNEQELYHATAAVTSLLLEIGEVGKLFVAQPAKEGGSGGSGPSCHQGIPGVLFPKKGPGQPYVVESVEPLPASLAPDSEEHSLGGQMEDIKLEDSSPRDNGACSSMLISDDDTKDDSSMSSYSVLSAGSHEEDKLHCEDIGEDTVLVRSGQGTAALPRSTSLDRDWAITFEQFLASLLTEPALVKYFDKPVCMMARITSAKNIRMMGKPLTSASDYEISAMSG", "length": 1266 }, "evidence": [ { "id": "MGI:1918560", "url": "https://alliancegenome.org/gene/MGI:1918560#orthology", "database": "AGR" }, { "id": "HGNC:21710", "url": "https://alliancegenome.org/gene/HGNC:21710#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060810-33", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-33#orthology", "database": "AGR" }, { "id": "F1Q7J9", "url": "https://omabrowser.org/oma/group/F1Q7J9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VP46-1", "protein_name": "TBC1 domain family member 8/9, isoform A", "gene_name": "Tbc1d8-9", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWIQPKELLLPSAFWIAEMHSRYFVLQKRRGHGESRGFGSMLVGTYDSVMNTKPAPYRILHQTPSSEVSYEIAIGITQDEIVKDWEWLKANLFKVLDEMENEDEVTNFTICKIQSLYTQNNQDDTGESADFKVMKSKFRQIFKMPEEERLVISYSATYVKNKIPRQGQLYISLNHVCFYSYMLGQEIKRIIRFAELEDISRNANTIYLKTTNNMTYNFTMLFNASDAHLLIEQLNKMAIQQLIHDPDSPVVDHDTSNFSRLGSKTSKKPVLLRDLTARQKSEEFRIYFRLPQSEIIDGKIKANIWTPYSKRFNSGFIYLSPNFFCFRSDVKDLVSVVIPMKTIKSVEKKDDGQQRFENQIVIITSENVPFMFAHIVDRAVLISKITDLLARVHVPLSRERAKYDISWSKQTALMNTFKTQFSAEIIQKQEEKMVRWEAHFRDFGRGIGMFRTTDVINLIVEGIPDKLRQEIWLIFSGAIHDKEMNPGLYEDLVEKAACIKNCFAHDEIDRDLPRSLPEHPAFQSTDGIGALRRVLQAYALRNPQVGYCQAMNIVSSVFLLFCDEENAFWMLASLCENLLPDYYKDKVVGAQIDQGVLNELVETHLPDLHGHLEQLGVIKMISISWFLTIFMSVISYESSLHILDCFFYEGAKIIFMISLQIIEWNRDKLLICQDDGEAMLVLQNYLEGVYNPEYQVPPTTDKRKMERKVQTQTVQTLIHEAYTKFGEDITQQRIEELRNKHRRLTMRQFDIDNEKTIVKAYVQNPYFNRSELHMLLTIIREEKHALKSLQQQQQKVQCPLSETPQLVPQSTSRPIQDAGASGGRYEAYSVSYEVFHTLFTELTPWRKCVSVDIGEKLFRLTDKKGTGVLDFGQLINALGLVCSNKNMEKLKLLYVLHLPPLLSKAEIERSRRPRPRTKDDAEEAFEAEDFFDNDASESMEALPSPSDHNFDADDFALISATQHLHNLAGISGNTFMDLSRTPNLSVNSNTSSLAHRSSTFYVDLPGFQGTATSTDAGRDEDELQRQLRQQGRYESIDTFSDISDLGAARITPPEAGVGADVVAGAASSAAADHMLLNVETISNFSQISDLVAATRLERVDSNATDLRSLGSLGYLLDQPDEGASNSQHSIPHMRKENFQLLWRSIIEIMGLVQDEEMQRAYENLLELGNSNIKKEPSLESFTQLNMGGDEQPDSNGNPTTPAPEPIGTTRLFVALEEELRQASGKSRTTTTSSGDSSSTNISESWHISITQFIATVLTVNSIVRGFQTPIQISEQIEQLQKKRRKCLSTNY", "length": 1291 }, "evidence": [ { "id": "MGI:1918560", "url": "https://alliancegenome.org/gene/MGI:1918560#orthology", "database": "AGR" }, { "id": "HGNC:21710", "url": "https://alliancegenome.org/gene/HGNC:21710#orthology", "database": "AGR" }, { "id": "F1Q7J9", "url": "https://omabrowser.org/oma/group/F1Q7J9/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "GTPase activator activity", "id": "GO:0005096", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005096", "evidence": [ { "database": "UniProtKB", "id": "F1Q7J9", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9" } ], "pmid": "" }, { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "F1Q7J9", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "F1Q7J9", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "system process", "id": "GO:0003008", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003008", "evidence": [ { "database": "UniProtKB", "id": "F1Q7J9", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1021, "end_pos": 1023, "annotation": "n_glycosylation_sequon" }, { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 236, "end_pos": 238, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1Q7J9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9" }, { "id": "PS50222", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50222" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EF-hand", "eco_id": "ECO_0000259", "start_pos": 884, "end_pos": 919, "start_aa": "His", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "F1Q7J9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q7J9" }, { "id": "PS50086", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50086" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Rab-GAP TBC", "eco_id": "ECO_0000259", "start_pos": 513, "end_pos": 700, "start_aa": "Gly", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1105 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1021, "end_pos": 1023 }, { "start_pos": 124, "end_pos": 126 }, { "start_pos": 236, "end_pos": 238 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "F1QAQ3-1", "uniprot_ac": "F1QAQ3", "uniprot_id": "F1QAQ3_DANRE", "mass": { "chemical_mass": 239927.0, "monoisotopic_mass": 239927.0 }, "refseq": { "ac": "XP_001919948", "name": "A-kinase anchor protein 6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919948" }, "gene_names": [ { "name": "akap6", "type": "recommended", "evidence": [ { "id": "F1QAQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3" } ] }, { "name": "akap6", "type": "synonym", "evidence": [ { "id": "XP_001919948", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919948" } ] } ], "protein_names": [ { "name": "A-kinase anchor protein 6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001919948", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919948" }, { "id": "F1QAQ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001919948.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001919948", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919948" } ] } ], "disease": [ { "disease_id": "DOID:2152", "recommended_name": { "id": "DOID:2152", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2152", "name": "ovary epithelial cancer", "description": "An ovarian cancer that is derives_from ovarian surface epithelium." }, "synonyms": [ { "id": "DOID:2152", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2152", "name": "Ovarian Surface epithelial-Stromal tumor", "description": "" } ], "unlinked_id_list": [ "DOID:2151" ], "evidence": [ { "id": "2152", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2152" } ] }, { "disease_id": "DOID:8689", "recommended_name": { "id": "DOID:8689", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8689", "name": "anorexia nervosa", "description": "An eating disorder characterized by refusal to maintain a healthy body weight, and an obsessive fear of gaining weight due to a distorted self image." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "8689", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8689" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QAQ3", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "akap6", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120207-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120207-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077295", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077295", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00176", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00176", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100002625", "url": "https://www.ncbi.nlm.nih.gov/gene/100002625", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100002625", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100002625", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1QAQ3", "url": "https://www.orthodb.org/?gene=F1QAQ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14514", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14514", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14514:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14514:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_001919948", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919948", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A2R8PW09", "url": "https://www.uniprot.org/uniprotkb/A0A2R8PW09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2R8PW09-1", "url": "https://www.uniprot.org/uniprotkb/A0A2R8PW09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PP43", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP43", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PP43-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PP43-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQJ3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQJ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQJ3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQJ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQJ6", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQJ9", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQJ9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQJ9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQJ9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQK0", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQK0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QAQ3", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QAQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120207-2", "url": "https://zfin.org/ZDB-GENE-120207-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNVVISPNASEASSPMITAVTPTLEPGPDKHDDPDVCEPSVSADGSTQKQDPYRRFQKPPPLHTGADWKVVLHLPEIETWLRTTTERVRDLTHSVQQDSSNRHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNIIVDIRSVQLLWHQLRVSVLVLKERLLQGLQDSNGNYTRQTDILQAFSQDHDQARLDALTEVDDSGQLTIKCSRDYFSLDCGITAYELSDYSPIEDPEGRGPHSLYPELEQDFPELLQSVDLLNIAASRQNQLSASSTEESVTSTQKPQETISSPTEKEEEGTTDSAMQDDSNFGLSKRPLHGGFRSELSPTQPLPKKPMYLEGDGDTRFSRPSPLQYQADLSRSTPSLLDTLDRTKFWLELESVYPGSGSQSYESLYGMNARNLQIGLKRSGQVPLERRLSEAEHEFSKQKHLSNPKTMHSKAKQAYSDSSSPPPSSGEDISDHEPRAMSSSPDDQAPATNSLWIMNQNALCISNASSNLKEHWYGSDEFLALPAQLKKTEILAMKLESLTQALPQRGLQESIQDVDDWELTEVNPDWESSTDLHLLHPYKKSSRTGRFSPTSSSDVAPSLDDSIESGPLSELMSEDEGARSTPESRARNVSSELPNVPKMMIQCTPLIKQLLADIQHQDNYDNVWTKIEGFVSKLDEFICWLRDALETTENWTPPRADIDNLRLYLETHLSFKLNVDSHSSLKDSLLEEGRQLLELITSHKSGLRDMLHMISQQWQELQRQIRRQHNWMLRTLDAIKTHILSSERSEDEAHSHHHSPKQVEVQQSHREAQKDILDQMRGKLQSQQLWSGSRGVDFSLMSRTSSLSEFEAEYQELWDWLMDMESIVTDSHDLMMSEEQQHHLYKGNSVEMSMWLPKKTHLLGWSESLKRSGSELPADFDQRLSALRSKWDQLQKTLSEHMVPSVVQQSQRELLSPDTSRMVTQLESRIKELKSWLRETELFIFNLNLRPDNAQQCESSAQDTTEEPQHEPQTSKQLQHFKALCVEVRGRRRGISSILRLCQRLLDGPEHQSSESKRQSLQLLQVNLERRWEAIIMQTLQWQSRLKRSLGRDQVPGNLIEPSLMDLHGLTEDSWEWDEMDMTINMETQNCEDEETPGSKSHLNSPKEPSSLTESCPTDTQCAPSSHVYQVYSLHNVELYQQPQYNHKSSPAKAQQSLLKRVSMDSSFSSAESLPDILGDLLRGKQRLLSDSARRSESESGIVSEGDTETLGNSEICLLCQSDDLKVCVTLTPPIREDSHNRDRVSDEDIDRVLERANKCAEYGDSLTIVKRDQRCHGTRKKRDDCGESRKKHRKEPVKILAKGLGLCQESGDENPSMSGDDERVTTHRKLQKEFAQLSQGSSLDSLYAVGELFPTSKETLTRSTSLESWLAPCKSAEDGGSKESLRDIGSTVEPTGELSRRTLELLKRLENIQSPLALKMTRSVSDVTLQSSSLWRGSRSAGAPSSINESSAASLTELSSTEDSSVASEDLAVQMNRCIAAESNASFRKHCHSQQQADETDASISMVVNISCTSACTDDEEDSDLLSSSTLTLTEEELGIKDDDSSVTSEEEYIEGSFALGLDYIKGEFQSWMKPRSQIREKNEADLVDELQCGTLSRDILSPIKTASDRQFLSRSALRLLEANTNAKNESLKHREVDGNRRDATRNYISCFVDDMENGNVESSHIKAKDEDDELLREEGSLLTKKGEPFKASYGVDATTGIKSNMLTTTSPSSCEQLSLGSLEGQLKGELPCHNSRRPSPSLSPIDDCSGLAAHTLSRQKQLAAFLNDVHENHQEGSSDCCSHPSFMSKEARSENVHDFVMEIIDLTSVARKTKEEPTEVCSPTSVSQIKEKVLEHSHRLIHLRKGDFYSYLSLSSHDSDCGEVSTCTEDKSSTPILSCSPDIRDEEPLFEACTEEVYLGPPLCYSMSISKRPTRHGAKLIEPLALLKPSSGCDEYQKAHGVSEASVAGSQSECHNEAPYLNPLPCETPIDTVECFADTKMLESNISPVMTKIRVSCSTTNPLKEDGSLYINPKINCPLIRKTDSDERAPASQLMKQKNVGKGRRSLLEARSTHKQLPRSESSSGVAQGCRAQISGAQTDSSSAGTTRVSSRPQVKRLSGSVTSSVSKP", "length": 2143, "header": "tr|F1QAQ3-1|F1QAQ3_DANRE Isoform 1 of A-kinase anchor protein 6 isoform X1 OS=Danio rerio OX=7955 GN=akap6 PE=4 SV=2 CANONICAL=F1QAQ3-1" }, "isoforms": [ { "isoform_ac": "A0A2R8PW09-1", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3/entry#A0A2R8PW09-1", "sequence": { "sequence": "MNVVISPNASEASSPMITAVTPTLEPGPDKHDDPDVCEPSVSADGSTQKQDPYRRFQKPPPLHTGADWKVVLHLPEIETWLRTTTERVRDLTHSVQQDSSNRHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNIIVDIRSVQLLWHQLRVSVLVLKERLLQGLQDSNGNYTRQTDILQAFSQDHDQARLDALTEVDDSGQLTIKCSRDYFSLDCGITAYELSDYSPIEDPEGRGPHSLYPELEQDFPELLQSVDLLNIAASRQNQLSASSTEESVTSTQKPQETISSPTEKEEEGTTDSAMQDDSNFGLSKRPLHGGFRSELSPTQPLPKKPMYLEGDGDTRFSRPSPLQYQADLSRSTPSLLDTLDRTKFWLELESVYPGSGSQSYESLYGMNARNLQIGLKRSGQVPLERRLSEAEHEFSKQKHLSNPKTMHSKAKQAYSDSSSPPPSSGEDISDHEPRAMSSSPDDQAPATNSLWIMNQNALCISNASSNLKEHWYGSDEFLALPAQLKKTEILAMKLESLTQALPQRGLQESIQDVDDWELTEVNPDWESSTDLHLLHPYKKSSRTGRFSPTSSSDVAPSLDDSIESGPLSELMSEDEGARSTPESRARNVSSELPNVPKMMIQCTPLIKQLLADIQHQDNYDNVWTKIEGFVSKLDEFICWLRDALETTENWTPPRADIDNLRLYLETHLSFKLNVDSHSSLKDSLLEEGRQLLELITSHKSGLRDMLHMISQQWQELQRQIRRQHNWMLRTLDAIKTHILSSERSEDEAHSHHHSPKQVEVQQSHREAQKDILDQMRGKLQSQQLWSGSRGVDFSLMSRTSSLSEFEAEYQELWDWLMDMESIVTDSHDLMMSEEQQHHLYKGNSVEMSMWLPKKTHLLGWSESLKRSGSELPADFDQRLSALRSKWDQLQKTLSEHMVPSVVQQSQRELLSPDTSRMVTQLESRIKELKSWLRETELFIFNLNLRPDNAQQCESSAQDTTEEPQHEPQTSKQLQHFKVPGNLIEPSLMDLHGLTEDSWEWDEMDMTINMETQNCEDEETPGSKSHLNSPKEPSSLTESCPTDTQCAPSSHVYQVYSLHNVELYQQPQYNHKSSPAKAQQSLLKRVSMDSSFSSAESLPDILGDLLRGKQRLLSDSARRSESESGIVSEGDTETLGNSEICLLCQSDDLKVCVTLTPPIREDSHNRDRVSDEDIDRVLERANKCAEYGDSLTIVKRDQRCHGTRKKRDDCGESRKKHRKEPVKILAKGLGLCQESGDENPSMSGDDERVTTHRKLQKEFAQLSQGSSLDSLYAVGELFPTSKETLTRSTSLESWLAPCKSAEDGGSKESLRDIGSTVEPTGELSRRTLELLKRLENIQSPLALKMTRSVSDVTLQSSSLWRGSRSAGAPSSINESSAASLTELSSTEDSSVASEDLAVQMNRCIAAESNASFRKHCHSQQQADETDASISMVVNISCTSACTDDEEDSDLLSSSTLTLTEEELGIKDDDSSVTSEEEYIEGSFALGLDYIKGEFQSWMKPRSQIREKNEADLVDELQCGTLSRDILSPIKTASDRQFLSRSALRLLEANTNAKNESLKHREVDGNRRDATRNYISCFVDDMENGNVESSHIKAKDEDDELLREEGSLLTKKGEPFKASYGVDATTGIKSNMLTTTSPSSCEQLSLGSLEGQLKGELPCHNSRRPSPSLSPIDDCSGLAAHTLSRQKQLAAFLNDVHENHQEGSSDCCSHPSFMSKEARSENVHDFVMEIIDLTSVARKTKEEPTEVCSPTSVSQIKEKVLEHSHRLIHLRKGDFYSYLSLSSHDSDCGEVSTCTEDKSSTPILSCSPDIRDEEPLFEACTEEVYLGPPLCYSMSISKRPTRHGAKLIEPLALLKPSSGCDEYQKAHGVSEASVAGSQSECHNEAPYLNPLPCETPIDTVECFADTKMLESNISPVMTKIRVSCSTTNPLKEDGSLYINPKINCPLIRKTDSDERAPASQLMKQKNVGKGRRSLLEARSTHKQLPRSESSSGVAQGCRAQISGAQTDSSSAGTTRVSSRPQVKRLSGSVTSSVSKP", "length": 2071, "header": "tr|A0A2R8PW09-1|F1QAQ3_DANRE Computationally mapped isoform of A-kinase anchor protein 6 isoform X1 OS=Danio rerio OX=7955 GN=akap6 PE=4 SV=1 CANONICAL=F1QAQ3-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PP43-1", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3/entry#A0A8M9PP43-1", "sequence": { "sequence": "MNVVISPNASEASSPMITAVTPTLEPGPDKHDDPDVCEPSVSADGSTQKQDPYRRFQKPPPLHTGADWKVVLHLPEIETWLRTTTERVRDLTHSVQQDSSNRHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNIIVDIRSVQLLWHQLRVSVLVLKERLLQGLQDSNGNYTRQTDILQAFSQDHDQARLDALTEVDDSGQLTIKCSRDYFSLDCGITAYELSDYSPIEDPEGRGPHSLYPELEQDFPELLQSVDLLNIAASRQNQLSASSTEESVTSTQKPQETISSPTEKEEEGTTDSAMQDDSNFGLSKRPLHGGFRSELSPTQPLPKKPMYLEGDGDTRFSRPSPLQYQADLSRSTPSLLDTLDRTKFWLELESVYPGSGSQSYESLYGMNARNLQIGLKRSGQVPLERRLSEAEHEFSKQKHLSNPKTMHSKAKQAYSDSSSPPPSSGEDISDHEPRAMSSSPDDQAPATNSLWIMNQNALCISNASSNLKEHWYGSDEFLALPAQLKKTEILAMKLESLTQALPQRGLQESIQDVDDWELTEVNPDWESSTDLHLLHPYKKSSRTGRFSPTSSSDVAPSLDDSIESGPLSELMSEDEGARSTPESRARNVSSELPNVPKMMIQCTPLIKQLLADIQHQDNYDNVWTKIEGFVSKLDEFICWLRDALETTENWTPPRADIDNLRLYLETHLSFKLNVDSHSSLKDSLLEEGRQLLELITSHKSGLRDMLHMISQQWQELQRQIRRQHNWMLRTLDAIKTHILSSERSEDEAHSHHHSPKVEVQQSHREAQKDILDQMRGKLQSQQLWSGSRGVDFSLMSRTSSLSEFEAEYQELWDWLMDMESIVTDSHDLMMSEEQQHHLYKGNSVEMSMWLPKKTHLLGWSESLKRSGSELPADFDQRLSALRSKWDQLQKTLSEHMVPSVVQQSQRELLSPDTSRMVTQLESRIKELKSWLRETELFIFNLNLRPDNAQQCESSAQDTTEEPQHEPQTSKQLQHFKALCVEVRGRRRGISSILRLCQRLLDGPEHQSSESKRQSLQLLQVNLERRWEAIIMQTLQWQSRLKRSLGRDQVPGNLIEPSLMDLHGLTEDSWEWDEMDMTINMETQNCEDEETPGSKSHLNSPKEPSSLTESCPTDTQCAPSSHVYQVYSLHNVELYQQPQYNHKSSPAKAQQSLLKRVSMDSSFSSAESLPDILGDLLRGKQRLLSDSARRSESESGIVSEGDTETLGNSEICLLCQSDDLKVCVTLTPPIREDSHNRDRVSDEDIDRVLERANKCAEYGDSLTIVKRDQRCHGTRKKRDDCGESRKKHRKEPVKILAKGLGLCQESGDENPSMSGDDERVTTHRKLQKEFAQLSQGSSLDSLYAVGELFPTSKETLTRSTSLESWLAPCKSAEDGGSKESLRDIGSTVEPTGELSRRTLELLKRLENIQSPLALKMTRSVSDVTLQSSSLWRGSRSAGAPSSINESSAASLTELSSTEDSSVASEDLAVQMNRCIAAESNASFRKHCHSQQQADETDASISMVVNISCTSACTDDEEDSDLLSSSTLTLTEEELGIKDDDSSVTSEEEYIEGSFALGLDYIKGEFQSWMKPRSQIREKNEADLVDELQCGTLSRDILSPIKTASDRQFLSRSALRLLEANTNAKNESLKHREVDGNRRDATRNYISCFVDDMENGNVESSHIKAKDEDDELLREEGSLLTKKGEPFKASYGVDATTGIKSNMLTTTSPSSCEQLSLGSLEGQLKGELPCHNSRRPSPSLSPIDDCSGLAAHTLSRQKQLAAFLNDVHENHQEGSSDCCSHPSFMSKEARSENVHDFVMEIIDLTSVARKTKEEPTEVCSPTSVSQIKEKVLEHSHRLIHLRKGDFYSYLSLSSHDSDCGEVSTCTEDKSSTPILSCSPDIRDEEPLFEACTEEVYLGPPLCYSMSISKRPTRHGAKLIEPLALLKPSSGCDEYQKAHGVSEASVAGSQSECHNEAPYLNPLPCETPIDTVECFADTKMLESNISPVMTKIRVSCSTTNPLKEDGSLYINPKINCPLIRKTDSDERAPASQLMKQKNVGKGRRSLLEARSTHKQLPRSESSSGVAQGCRAQISGAQTDSSSAGTTRVSSRPQVKRLSGSVTSSVSKP", "length": 2142, "header": "tr|A0A8M9PP43-1|F1QAQ3_DANRE Computationally mapped isoform of A-kinase anchor protein 6 isoform X1 OS=Danio rerio OX=7955 GN=akap6 PE=4 SV=1 CANONICAL=F1QAQ3-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQJ3-1", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3/entry#A0AC58HQJ3-1", "sequence": { "sequence": "MQDDSNFGLSKRPLHGGFRSELSPTQPLPKKPMYLEGDGDTRFSRPSPLQYQADLSRSTPSLLDTLDRTKFWLELESVYPGSGSQSYESLYGMNARNLQIGLKRSGQVPLERRLSEAEHEFSKQKHLSNPKTMHSKAKQAYSDSSSPPPSSGEDISDHEPRAMSSSPDDQAPATNSLWIMNQNALCISNASSNLKEHWYGSDEFLALPAQLKKTEILAMKLESLTQALPQRGLQESIQDVDDWELTEVNPDWESSTDLHLLHPYKKSSRTGRFSPTSSSDVAPSLDDSIESGPLSELMSEDEGARSTPESRARNVSSELPNVPKMMIQCTPLIKQLLADIQHQDNYDNVWTKIEGFVSKLDEFICWLRDALETTENWTPPRADIDNLRLYLETHLSFKLNVDSHSSLKDSLLEEGRQLLELITSHKSGLRDMLHMISQQWQELQRQIRRQHNWMLRTLDAIKTHILSSERSEDEAHSHHHSPKQVEVQQSHREAQKDILDQMRGKLQSQQLWSGSRGVDFSLMSRTSSLSEFEAEYQELWDWLMDMESIVTDSHDLMMSEEQQHHLYKGNSVEMSMWLPKKTHLLGWSESLKRSGSELPADFDQRLSALRSKWDQLQKTLSEHMVPSVVQQSQRELLSPDTSRMVTQLESRIKELKSWLRETELFIFNLNLRPDNAQQCESSAQDTTEEPQHEPQTSKQLQHFKVPGNLIEPSLMDLHGLTEDSWEWDEMDMTINMETQNCEDEETPGSKSHLNSPKEPSSLTESCPTDTQCAPSSHVYQVYSLHNVELYQQPQYNHKSSPAKAQQSLLKRVSMDSSFSSAESLPDILGDLLRGKQRLLSDSARRSESESGIVSEGDTETLGNSEICLLCQSDDLKVCVTLTPPIREDSHNRDRVSDEDIDRVLERANKCAEYGDSLTIVKRDQRCHGTRKKRDDCGESRKKHRKEPVKILAKGLGLCQESGDENPSMSGDDERVTTHRKLQKEFAQLSQGSSLDSLYAVGELFPTSKETLTRSTSLESWLAPCKSAEDGGSKESLRDIGSTVEPTGELSRRTLELLKRLENIQSPLALKMTRSVSDVTLQSSSLWRGSRSAGAPSSINESSAASLTELSSTEDSSVASEDLAVQMNRCIAAESNASFRKHCHSQQQADETDASISMVVNISCTSACTDDEEDSDLLSSSTLTLTEEELGIKDDDSSVTSEEEYIEGSFALGLDYIKGEFQSWMKPRSQIREKNEADLVDELQCGTLSRDILSPIKTASDRQFLSRSALRLLEANTNAKNESLKHREVDGNRRDATRNYISCFVDDMENGNVESSHIKAKDEDDELLREEGSLLTKKGEPFKASYGVDATTGIKSNMLTTTSPSSCEQLSLGSLEGQLKGELPCHNSRRPSPSLSPIDDCSGLAAHTLSRQKQLAAFLNDVHENHQEGSSDCCSHPSFMSKEARSENVHDFVMEIIDLTSVARKTKEEPTEVCSPTSVSQIKEKVLEHSHRLIHLRKGDFYSYLSLSSHDSDCGEVSTCTEDKSSTPILSCSPDIRDEEPLFEACTEEVYLGPPLCYSMSISKRPTRHGAKLIEPLALLKPSSGCDEYQKAHGVSEASVAGSQSECHNEAPYLNPLPCETPIDTVECFADTKMLESNISPVMTKIRVSCSTTNPLKEDGSLYINPKINCPLIRKTDSDERAPASQLMKQKNVGKGRRSLLEARSTHKQLPRSESSSGVAQGCRAQISGAQTDSSSAGTTRVSSRPQVKRLSGSVTSSVSKP", "length": 1761, "header": "tr|A0AC58HQJ3-1|A0AC58HQJ3_DANRE Computationally mapped isoform of A-kinase anchor protein 6 isoform X7 OS=Danio rerio OX=7955 GN=akap6 PE=4 SV=1 CANONICAL=F1QAQ3-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQJ6-1", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3/entry#A0AC58HQJ6-1", "sequence": { "sequence": "MQDDSNFGLSKRPLHGGFRSELSPTQPLPKKPMYLEGDGDTRFSRPSPLQYQADLSRSTPSLLDTLDRTKFWLELESVYPGSGSQSYESLYGMNARNLQIGLKRSGQVPLERRLSEAEHEFSKQKHLSNPKTMHSKAKQAYSDSSSPPPSSGEDISDHEPRAMSSSPDDQAPATNSLWIMNQNALCISNASSNLKEHWYGSDEFLALPAQLKKTEILAMKLESLTQALPQRGLQESIQDVDDWELTEVNPDWESSTDLHLLHPYKKSSRTGRFSPTSSSDVAPSLDDSIESGPLSELMSEDEGARSTPESRARNVSSELPNVPKMMIQCTPLIKQLLADIQHQDNYDNVWTKIEGFVSKLDEFICWLRDALETTENWTPPRADIDNLRLYLETHLSFKLNVDSHSSLKDSLLEEGRQLLELITSHKSGLRDMLHMISQQWQELQRQIRRQHNWMLRTLDAIKTHILSSERSEDEAHSHHHSPKQVEVQQSHREAQKDILDQMRGKLQSQQLWSGSRGVDFSLMSRTSSLSEFEAEYQELWDWLMDMESIVTDSHDLMMSEEQQHHLYKGNSVEMSMWLPKKTHLLGWSESLKRSGSELPADFDQRLSALRSKWDQLQKTLSEHMVPSVVQQSQRELLSPDTSRMVTQLESRIKELKSWLRETELFIFNLNLRPDNAQQCESSAQDTTEEPQHEPQTSKQLQHFKALCVEVRGRRRGISSILRLCQRLLDGPEHQSSESKRQSLQLLQVNLERRWEAIIMQTLQWQSRLKRSLGRDQVPGNLIEPSLMDLHGLTEDSWEWDEMDMTINMETQNCEDEETPGSKSHLNSPKEPSSLTESCPTDTQCAPSSHVYQVYSLHNVELYQQPQYNHKSSPAKAQQSLLKRVSMDSSFSSAESLPDILGDLLRGKQRLLSDSARRSESESGIVSEGDTETLGNSEICLLCQSDDLKVCVTLTPPIREDSHNRDRVSDEDIDRVLERANKCAEYGDSLTIVKRDQRCHGTRKKRDDCGESRKKHRKEPVKILAKGLGLCQESGDENPSMSGDDERVTTHRKLQKEFAQLSQGSSLDSLYAVGELFPTSKETLTRSTSLESWLAPCKSAEDGGSKESLRDIGSTVEPTGELSRRTLELLKRLENIQSPLALKMTRSVSDVTLQSSSLWRGSRSAGAPSSINESSAASLTELSSTEDSSVASEDLAVQMNRCIAAESNASFRKHCHSQQQADETDASISMVVNISCTSACTDDEEDSDLLSSSTLTLTEEELGIKDDDSSVTSEEEYIEGSFALGLDYIKGEFQSWMKPRSQIREKNEADLVDELQCGTLSRDILSPIKTASDRQFLSRSALRLLEANTNAKNESLKHREVDGNRRDATRNYISCFVDDMENGNVESSHIKAKDEDDELLREEGSLLTKKGEPFKASYGVDATTGIKSNMLTTTSPSSCEQLSLGSLEGQLKGELPCHNSRRPSPSLSPIDDCSGLAAHTLSRQKQLAAFLNDVHENHQEGSSDCCSHPSFMSKEARSENVHDFVMEIIDLTSVARKTKEEPTEVCSPTSVSQIKEKVLEHSHRLIHLRKGDFYSYLSLSSHDSDCGEVSTCTEDKSSTPILSCSPDIRDEEPLFEACTEEVYLGPPLCYSMSISKRPTRHGAKLIEPLALLKPSSGCDEYQKAHGVSEASVAGSQSECHNEAPYLNPLPCETPIDTVECFADTKMLESNISPVMTKIRVSCSTTNPLKEDGSLYINPKINCPLIRKTDSDERAPASQLMKQKNVGKGRRSLLEARSTHKQLPRSESSSGVAQGCRAQISGAQTDSSSAGTTRVSSRPQVKRLSGSVTSSVSKP", "length": 1833, "header": "tr|A0AC58HQJ6-1|A0AC58HQJ6_DANRE Computationally mapped isoform of A-kinase anchor protein 6 isoform X5 OS=Danio rerio OX=7955 GN=akap6 PE=4 SV=1 CANONICAL=F1QAQ3-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQJ9-1", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3/entry#A0AC58HQJ9-1", "sequence": { "sequence": "MNVVISPNASEASSPMITAVTPTLEPGPDKHDDPDVCEPSVSADGSTQKQDPYRRFQKPPPLHTGADWKVVLHLPEIETWLRTTTERVRDLTHSVQQDSSNRHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNIIVDIRSVQLLWHQLRVSVLVLKERLLQGLQDSNGNYTRQTDILQAFSQDHDQARLDALTEVDDSGQLTIKCSRDYFSLDCGITAYELSDYSPIEDPEGRGPHSLYPELEQDFPELLQSVDLLNIAASRQNQLSASSTEESVTSTQKPQETISSPTEKEEEGTTDSAMQDDSNFGLSKRPLHGGFRSELSPTQPLPKKPMYLEGDGDTRFSRPSPLQYQADLSRSTPSLLDTLDRTKFWLELESVYPGSGSQSYESLYGMNARNLQIGLKRSGQVPLERRLSEAEHEFSKQKHLSNPKTMHSKAKQAYSDSSSPPPSSGEDISDHEPRAMSSSPDDQAPATNSLWIMNQNALCISNASSNLKEHWYGSDEFLALPAQLKKTEILAMKLESLTQALPQRGLQESIQDVDDWELTEVNPDWESSTDLHLLHPYKKSSRTGRFSPTSSSDVAPSLDDSIESGPLSELMSEDEGARSTPESRARNVSSELPNVPKMMIQCTPLIKQLLADIQHQDNYDNVWTKIEGFVSKLDEFICWLRDALETTENWTPPRADIDNLRLYLETHLSFKLNVDSHSSLKDSLLEEGRQLLELITSHKSGLRDMLHMISQQWQELQRQIRRQHNWMLRTLDAIKTHILSSERSEDEAHSHHHSPKVEVQQSHREAQKDILDQMRGKLQSQQLWSGSRGVDFSLMSRTSSLSEFEAEYQELWDWLMDMESIVTDSHDLMMSEEQQHHLYKGNSVEMSMWLPKKTHLLGWSESLKRSGSELPADFDQRLSALRSKWDQLQKTLSEHMVPSVVQQSQRELLSPDTSRMVTQLESRIKELKSWLRETELFIFNLNLRPDNAQQCESSAQDTTEEPQHEPQTSKQLQHFKVPGNLIEPSLMDLHGLTEDSWEWDEMDMTINMETQNCEDEETPGSKSHLNSPKEPSSLTESCPTDTQCAPSSHVYQVYSLHNVELYQQPQYNHKSSPAKAQQSLLKRVSMDSSFSSAESLPDILGDLLRGKQRLLSDSARRSESESGIVSEGDTETLGNSEICLLCQSDDLKVCVTLTPPIREDSHNRDRVSDEDIDRVLERANKCAEYGDSLTIVKRDQRCHGTRKKRDDCGESRKKHRKEPVKILAKGLGLCQESGDENPSMSGDDERVTTHRKLQKEFAQLSQGSSLDSLYAVGELFPTSKETLTRSTSLESWLAPCKSAEDGGSKESLRDIGSTVEPTGELSRRTLELLKRLENIQSPLALKMTRSVSDVTLQSSSLWRGSRSAGAPSSINESSAASLTELSSTEDSSVASEDLAVQMNRCIAAESNASFRKHCHSQQQADETDASISMVVNISCTSACTDDEEDSDLLSSSTLTLTEEELGIKDDDSSVTSEEEYIEGSFALGLDYIKGEFQSWMKPRSQIREKNEADLVDELQCGTLSRDILSPIKTASDRQFLSRSALRLLEANTNAKNESLKHREVDGNRRDATRNYISCFVDDMENGNVESSHIKAKDEDDELLREEGSLLTKKGEPFKASYGVDATTGIKSNMLTTTSPSSCEQLSLGSLEGQLKGELPCHNSRRPSPSLSPIDDCSGLAAHTLSRQKQLAAFLNDVHENHQEGSSDCCSHPSFMSKEARSENVHDFVMEIIDLTSVARKTKEEPTEVCSPTSVSQIKEKVLEHSHRLIHLRKGDFYSYLSLSSHDSDCGEVSTCTEDKSSTPILSCSPDIRDEEPLFEACTEEVYLGPPLCYSMSISKRPTRHGAKLIEPLALLKPSSGCDEYQKAHGVSEASVAGSQSECHNEAPYLNPLPCETPIDTVECFADTKMLESNISPVMTKIRVSCSTTNPLKEDGSLYINPKINCPLIRKTDSDERAPASQLMKQKNVGKGRRSLLEARSTHKQLPRSESSSGVAQGCRAQISGAQTDSSSAGTTRVSSRPQVKRLSGSVTSSVSKP", "length": 2070, "header": "tr|A0AC58HQJ9-1|A0AC58HQJ9_DANRE Computationally mapped isoform of A-kinase anchor protein 6 isoform X4 OS=Danio rerio OX=7955 GN=akap6 PE=4 SV=1 CANONICAL=F1QAQ3-1" }, "locus": {} }, { "isoform_ac": "A0AC58HQK0-1", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3/entry#A0AC58HQK0-1", "sequence": { "sequence": "MQDDSNFGLSKRPLHGGFRSELSPTQPLPKKPMYLEGDGDTRFSRPSPLQYQADLSRSTPSLLDTLDRTKFWLELESVYPGSGSQSYESLYGMNARNLQIGLKRSGQVPLERRLSEAEHEFSKQKHLSNPKTMHSKAKQAYSDSSSPPPSSGEDISDHEPRAMSSSPDDQAPATNSLWIMNQNALCISNASSNLKEHWYGSDEFLALPAQLKKTEILAMKLESLTQALPQRGLQESIQDVDDWELTEVNPDWESSTDLHLLHPYKKSSRTGRFSPTSSSDVAPSLDDSIESGPLSELMSEDEGARSTPESRARNVSSELPNVPKMMIQCTPLIKQLLADIQHQDNYDNVWTKIEGFVSKLDEFICWLRDALETTENWTPPRADIDNLRLYLETHLSFKLNVDSHSSLKDSLLEEGRQLLELITSHKSGLRDMLHMISQQWQELQRQIRRQHNWMLRTLDAIKTHILSSERSEDEAHSHHHSPKVEVQQSHREAQKDILDQMRGKLQSQQLWSGSRGVDFSLMSRTSSLSEFEAEYQELWDWLMDMESIVTDSHDLMMSEEQQHHLYKGNSVEMSMWLPKKTHLLGWSESLKRSGSELPADFDQRLSALRSKWDQLQKTLSEHMVPSVVQQSQRELLSPDTSRMVTQLESRIKELKSWLRETELFIFNLNLRPDNAQQCESSAQDTTEEPQHEPQTSKQLQHFKALCVEVRGRRRGISSILRLCQRLLDGPEHQSSESKRQSLQLLQVNLERRWEAIIMQTLQWQSRLKRSLGRDQVPGNLIEPSLMDLHGLTEDSWEWDEMDMTINMETQNCEDEETPGSKSHLNSPKEPSSLTESCPTDTQCAPSSHVYQVYSLHNVELYQQPQYNHKSSPAKAQQSLLKRVSMDSSFSSAESLPDILGDLLRGKQRLLSDSARRSESESGIVSEGDTETLGNSEICLLCQSDDLKVCVTLTPPIREDSHNRDRVSDEDIDRVLERANKCAEYGDSLTIVKRDQRCHGTRKKRDDCGESRKKHRKEPVKILAKGLGLCQESGDENPSMSGDDERVTTHRKLQKEFAQLSQGSSLDSLYAVGELFPTSKETLTRSTSLESWLAPCKSAEDGGSKESLRDIGSTVEPTGELSRRTLELLKRLENIQSPLALKMTRSVSDVTLQSSSLWRGSRSAGAPSSINESSAASLTELSSTEDSSVASEDLAVQMNRCIAAESNASFRKHCHSQQQADETDASISMVVNISCTSACTDDEEDSDLLSSSTLTLTEEELGIKDDDSSVTSEEEYIEGSFALGLDYIKGEFQSWMKPRSQIREKNEADLVDELQCGTLSRDILSPIKTASDRQFLSRSALRLLEANTNAKNESLKHREVDGNRRDATRNYISCFVDDMENGNVESSHIKAKDEDDELLREEGSLLTKKGEPFKASYGVDATTGIKSNMLTTTSPSSCEQLSLGSLEGQLKGELPCHNSRRPSPSLSPIDDCSGLAAHTLSRQKQLAAFLNDVHENHQEGSSDCCSHPSFMSKEARSENVHDFVMEIIDLTSVARKTKEEPTEVCSPTSVSQIKEKVLEHSHRLIHLRKGDFYSYLSLSSHDSDCGEVSTCTEDKSSTPILSCSPDIRDEEPLFEACTEEVYLGPPLCYSMSISKRPTRHGAKLIEPLALLKPSSGCDEYQKAHGVSEASVAGSQSECHNEAPYLNPLPCETPIDTVECFADTKMLESNISPVMTKIRVSCSTTNPLKEDGSLYINPKINCPLIRKTDSDERAPASQLMKQKNVGKGRRSLLEARSTHKQLPRSESSSGVAQGCRAQISGAQTDSSSAGTTRVSSRPQVKRLSGSVTSSVSKP", "length": 1832, "header": "tr|A0AC58HQK0-1|A0AC58HQK0_DANRE Computationally mapped isoform of A-kinase anchor protein 6 isoform X6 OS=Danio rerio OX=7955 GN=akap6 PE=4 SV=1 CANONICAL=F1QAQ3-1" }, "locus": {} }, { "isoform_ac": "F1QAQ3-1", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3/entry#F1QAQ3-1", "sequence": { "sequence": "MNVVISPNASEASSPMITAVTPTLEPGPDKHDDPDVCEPSVSADGSTQKQDPYRRFQKPPPLHTGADWKVVLHLPEIETWLRTTTERVRDLTHSVQQDSSNRHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNIIVDIRSVQLLWHQLRVSVLVLKERLLQGLQDSNGNYTRQTDILQAFSQDHDQARLDALTEVDDSGQLTIKCSRDYFSLDCGITAYELSDYSPIEDPEGRGPHSLYPELEQDFPELLQSVDLLNIAASRQNQLSASSTEESVTSTQKPQETISSPTEKEEEGTTDSAMQDDSNFGLSKRPLHGGFRSELSPTQPLPKKPMYLEGDGDTRFSRPSPLQYQADLSRSTPSLLDTLDRTKFWLELESVYPGSGSQSYESLYGMNARNLQIGLKRSGQVPLERRLSEAEHEFSKQKHLSNPKTMHSKAKQAYSDSSSPPPSSGEDISDHEPRAMSSSPDDQAPATNSLWIMNQNALCISNASSNLKEHWYGSDEFLALPAQLKKTEILAMKLESLTQALPQRGLQESIQDVDDWELTEVNPDWESSTDLHLLHPYKKSSRTGRFSPTSSSDVAPSLDDSIESGPLSELMSEDEGARSTPESRARNVSSELPNVPKMMIQCTPLIKQLLADIQHQDNYDNVWTKIEGFVSKLDEFICWLRDALETTENWTPPRADIDNLRLYLETHLSFKLNVDSHSSLKDSLLEEGRQLLELITSHKSGLRDMLHMISQQWQELQRQIRRQHNWMLRTLDAIKTHILSSERSEDEAHSHHHSPKQVEVQQSHREAQKDILDQMRGKLQSQQLWSGSRGVDFSLMSRTSSLSEFEAEYQELWDWLMDMESIVTDSHDLMMSEEQQHHLYKGNSVEMSMWLPKKTHLLGWSESLKRSGSELPADFDQRLSALRSKWDQLQKTLSEHMVPSVVQQSQRELLSPDTSRMVTQLESRIKELKSWLRETELFIFNLNLRPDNAQQCESSAQDTTEEPQHEPQTSKQLQHFKALCVEVRGRRRGISSILRLCQRLLDGPEHQSSESKRQSLQLLQVNLERRWEAIIMQTLQWQSRLKRSLGRDQVPGNLIEPSLMDLHGLTEDSWEWDEMDMTINMETQNCEDEETPGSKSHLNSPKEPSSLTESCPTDTQCAPSSHVYQVYSLHNVELYQQPQYNHKSSPAKAQQSLLKRVSMDSSFSSAESLPDILGDLLRGKQRLLSDSARRSESESGIVSEGDTETLGNSEICLLCQSDDLKVCVTLTPPIREDSHNRDRVSDEDIDRVLERANKCAEYGDSLTIVKRDQRCHGTRKKRDDCGESRKKHRKEPVKILAKGLGLCQESGDENPSMSGDDERVTTHRKLQKEFAQLSQGSSLDSLYAVGELFPTSKETLTRSTSLESWLAPCKSAEDGGSKESLRDIGSTVEPTGELSRRTLELLKRLENIQSPLALKMTRSVSDVTLQSSSLWRGSRSAGAPSSINESSAASLTELSSTEDSSVASEDLAVQMNRCIAAESNASFRKHCHSQQQADETDASISMVVNISCTSACTDDEEDSDLLSSSTLTLTEEELGIKDDDSSVTSEEEYIEGSFALGLDYIKGEFQSWMKPRSQIREKNEADLVDELQCGTLSRDILSPIKTASDRQFLSRSALRLLEANTNAKNESLKHREVDGNRRDATRNYISCFVDDMENGNVESSHIKAKDEDDELLREEGSLLTKKGEPFKASYGVDATTGIKSNMLTTTSPSSCEQLSLGSLEGQLKGELPCHNSRRPSPSLSPIDDCSGLAAHTLSRQKQLAAFLNDVHENHQEGSSDCCSHPSFMSKEARSENVHDFVMEIIDLTSVARKTKEEPTEVCSPTSVSQIKEKVLEHSHRLIHLRKGDFYSYLSLSSHDSDCGEVSTCTEDKSSTPILSCSPDIRDEEPLFEACTEEVYLGPPLCYSMSISKRPTRHGAKLIEPLALLKPSSGCDEYQKAHGVSEASVAGSQSECHNEAPYLNPLPCETPIDTVECFADTKMLESNISPVMTKIRVSCSTTNPLKEDGSLYINPKINCPLIRKTDSDERAPASQLMKQKNVGKGRRSLLEARSTHKQLPRSESSSGVAQGCRAQISGAQTDSSSAGTTRVSSRPQVKRLSGSVTSSVSKP", "length": 2143, "header": "tr|F1QAQ3-1|F1QAQ3_DANRE Isoform 1 of A-kinase anchor protein 6 isoform X1 OS=Danio rerio OX=7955 GN=akap6 PE=4 SV=2 CANONICAL=F1QAQ3-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 21, "start_aa": "Thr", "end_pos": 21, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr21", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100002625", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100002625", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E9Q9K8-1", "protein_name": "A-kinase anchor protein 6", "gene_name": "Akap6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLTMSVTLSPLRSQDPDPMATDASPMAINMTPTVEQEEGEGEEAVKDVGAEQQYGKPPPLHTAADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDADSKHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLVLRERILQGLQDANGNYTRQTDILQAFSEETTEGRLDSLTEVDDSGQLTIKCSQNYLSLDCGITAFELSDYSPSEDLLGGLGDMTTSQAKTKSFDSWSYSEMEKEFPELIRSVGLLTVATEPVPSSCGAANEDSSQVILSEDHRGGHEEDGALEPGEQLGSTLETSSLGDTLTNAAEHPPETANQDSTSSPQLGAKKSQPGPCEMMTPKRSIRDCFNYNEDSPTQPTLPKRGLFLKETLKNERRGSDGKGRVVDLKPELSRSTPSLVEPPDRSKLCLVLQSSYPSSPSAASQSYECLHKVGIGNLENIVRSHIKEISSSLGRLTDCHKEKPRLKKPHKTLAEVSLCKIPKRGTGSGKQSENTRSSVVPTMVSPGAPKATARPATDSASTTSGDTCHQRNRGGKLPAQSKASSSSPCSHSSESSLGSDNIKSPLPLLSKSQKGSPPAPCHATQNGQVVEAWYGSDEYLALPSHLKQTEVLALKLENLTKLLPQKPRGETIQDIDDWELSEMNSDSEIYPTYHIKKKHTRLGTVSPSSSSDIASSLGESIESGPLSDILSDEDLCMPLSGMKKFTDEKSERPSSSEKNESHSATKSALIQKLMKDIQHQDNYEAIWERIEGFVNKLDEFIQWLNEAMETTENWTPPKAETDSLRLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHKAGLKDMLKMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVSVEDEEGTGSPKAEAQLCYLEAQRDAVEQMSLKLYSEQYTSGSKRKEEFADMSKAHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELLSKVEALKKGGLSLPNDILEKVDSINEKWELLGKTLREKIQDTMAGHSGSGPRDLLSPESGSLVRQLEVRIKELKRWLRDTELFIFNSCLRQEKEGTSAEKQLQYFKSLCHEIKQRRRGVASILRLCQHLLDDRDTCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLRKKMGKESETLNVIDPGLMDLNGMSEDALEWDETDISNKLISVHEESNDLDQDLEPMVPTVKLEETHHKDSGYEEEAGDCGGSQYTSNITAPSSPHIYQVYSLHNVEFHEDSHTQFLKSSPKFTGTVQPTVLTKSLSKDSSFSSTKSLPDLLGGSSLVRPYSCQSGDLSQNSGSESGIVSEGDNEMPTNSDMSLFSMVDGSPSNPETQHLDPQMGDAANVLEQKFKDEGECIKLSSVSQASVSPVGCVNGKAGDLNSITKHTTDCLGDELQGKHEVFTFYDYSYLQGSKLKFPMIMKQPQSEKAHLEDPLLRGFYFDKKSCKPKHQTSESQPDAPLHEKILASAPHEMGRSSYKSSDIEKALTGIQNARQLSLLSRSSSVESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFSGQMSLDVASSINEDSPASLTELSSSDELSLCSEDIVLHKNKVPESNASFRKRLNRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCLKDEDDDSSIATDDEIYEESNLMSGLDYIKNELQTWIRPKLSLSREKKRPSVTDEIKVNKDGGSTERANPSDTLDIEALLNCSIKRLSENNGNGKNPPRTHDLGTKGENKKNTYDVTKDPHVADMENGNVESTPEREKEKPEIPEASANLASNVKKISESKHDEYEALMDGSDDSSVTGKEFGPPNDRHPPQIGADPQHPERGDCTSVQNSCSGLLLETGGGSRQDSDGLKSLSNDAPSVARNAAGCCLLEQNETEESASISSSTSCCNCKPDVFHQKDDEDCSVHDFVKEIIDMASTALKSKSQPESEVAAPTSLTQIKEKVLEHSHRPIHLRKGDFYSYLSLSSHDSDCGEVTNYIDEKSNTPLPPDTVDSGLDDKEDVDCFFEACVEDEPADEEARLSSALPNESEVQDEAAKPEQMTASSSVFRDETDTVPLSGLSPQKGADDAKEGDGASHTSQGCVESAEPTTPPGKAKREGSSRKQSVSGTPEENAASAKPKIQAFSLNAKQPKGKAALYPSPQTLTCKEKLVSFHEDRHSNMHR", "length": 2307 }, "evidence": [ { "id": "HGNC:376", "url": "https://alliancegenome.org/gene/HGNC:376#orthology", "database": "AGR" }, { "id": "MGI:3050566", "url": "https://alliancegenome.org/gene/MGI:3050566#orthology", "database": "AGR" }, { "id": "RGD:69412", "url": "https://alliancegenome.org/gene/RGD:69412#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120207-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120207-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q13023-1", "protein_name": "A-kinase anchor protein 6", "gene_name": "AKAP6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLTMSVTLSPLRSQDLDPMATDASPMAINMTPTVEQGEGEEAMKDMDSDQQYEKPPPLHTGADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDSDSKHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLVLRERILQGLQDANGNYTRQTDILQAFSEETKEGRLDSLTEVDDSGQLTIKCSQNYLSLDCGITAFELSDYSPSEDLLSGLGDMTSSQVKTKPFDSWSYSEMEKEFPELIRSVGLLTVAADSISTNGSEAVTEEVSQVSLSVDDKGGCEEDNASAVEEQPGLTLGVSSSSGEALTNAAQPSSETVQQESSSSSHHDAKNQQPVPCENATPKRTIRDCFNYNEDSPTQPTLPKRGLFLKEETFKNDLKGNGGKRQMVDLKPEMSRSTPSLVDPPDRSKLCLVLQSSYPNSPSAASQSYECLHKVGNGNLENTVKFHIKEISSSLGRLNDCYKEKSRLKKPHKTSEEVPPCRTPKRGTGSGKQAKNTKSSAVPNGELSYTSKAIEGPQTNSASTSSLEPCNQRSWNAKLQLQSETSSSPAFTQSSESSVGSDNIMSPVPLLSKHKSKKGQASSPSHVTRNGEVVEAWYGSDEYLALPSHLKQTEVLALKLENLTKLLPQKPRGETIQNIDDWELSEMNSDSEIYPTYHVKKKHTRLGRVSPSSSSDIASSLGESIESGPLSDILSDEESSMPLAGMKKYADEKSERASSSEKNESHSATKSALIQKLMQDIQHQDNYEAIWEKIEGFVNKLDEFIQWLNEAMETTENWTPPKAEMDDLKLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELIASHKAGLKDMLRMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCYLEAQRDAVEQMSLKLYSEQYTSSSKRKEEFADMSKVHSVGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKTELLSKVEALKKGGVLLPNDLLEKVDSINEKWELLGKTLGEKIQDTMAGHSGSSPRDLLSPESGSLVRQLEVRIKELKGWLRDTELFIFNSCLRQEKEGTMNTEKQLQYFKSLCREIKQRRRGVASILRLCQHLLDDRETCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDEMDISNKLISLNEESNDLDQELQPVIPSLKLGETSNEDPGYDEEADNHGGSQYASNITAPSSPHIYQVYSLHNVELYEDNHMPFLKNNPKVTGMTQPNVLTKSLSKDSSFSSTKSLPDLLGGSNLVKPCACHGGDMSQNSGSESGIVSEGDTETTTNSEMCLLNAVDGSPSNLETEHLDPQMGDAVNVLKQKFTDEGESIKLPNSSQSSISPVGCVNGKVGDLNSITKHTPDCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQSQSEKAHVEDPLLRGFYFDKKSCKSKHQTTELQPDVPPHERILASASHEMDRISYKSGNIEKTFTGMQNAKQLSLLSHSSSIESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDITLQSSSQKMSFTGQMSLDIASSINEDSAASLTELSSSDELSLCSEDIVLHKNKIPESNASFRKRLTRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCIKDEDDDSSIATDDEIYEDCTLMSGLDYIKNELQTWIRPKLSLTRDKKRCNVSDEMKGSKDISSSEMTNPSDTLNIETLLNGSVKRVSENNGNGKNSSHTHELGTKRENKKTIFKVNKDPYVADMENGNIEGIPERQKGKPNVTSKVSENLGSHGKEISESEHCKCKALMDSLDDSNTAGKEFVSQDVRHLPKKCPNHHHFENQSTASTPTEKSFSELALETRFNNRQDSDALKSSDDAPSMAGKSAGCCLALEQNGTEENASISNISCCNCEPDVFHQKDAEDCSVHNFVKEIIDMASTALKSKSQPENEVAAPTSLTQIKEKVLEHSHRPIQLRKGDFYSYLSLSSHDSDCGEVTNYIEEKSSTPLPLDTTDSGLDDKEDIECFFEACVEGDSDGEEPCFSSAPPNESAVPSEAAMPLQATACSSEFSDSSLSADDADTVALSSPSSQERAEVGKEVNGLPQTSSGCAENLEFTPSKLDSEKESSGKPGESGMPEEHNAASAKSKVQDLSLKANQPTDKAALHPSPKTLTCEENLLNLHEKRHRNMHR", "length": 2319 }, "evidence": [ { "id": "HGNC:376", "url": "https://alliancegenome.org/gene/HGNC:376#orthology", "database": "AGR" }, { "id": "MGI:3050566", "url": "https://alliancegenome.org/gene/MGI:3050566#orthology", "database": "AGR" }, { "id": "RGD:69412", "url": "https://alliancegenome.org/gene/RGD:69412#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120207-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120207-2#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9WVC7-1", "protein_name": "A-kinase anchor protein 6", "gene_name": "Akap6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLTMSVTLSPLRSQGPDPMATDASPMAINMTPTVEQEEGEGEEAVKAIDAEQQYGKPPPLHTAADWKIVLHLPEIETWLRMTSERVRDLTYSVQQDADSKHVDVHLVQLKDICEDISDHVEQIHALLETEFSLKLLSYSVNVIVDIHAVQLLWHQLRVSVLVLRERILQGLQDANGNYTRQTDILQAFSEETTEGRLDSLTEVDDSGQLTIKCSQDYLSLDCGITAFELSDYSPSEDLLGGLGDMTTSQAKTKSFDSWSYSEMEKEFPELIRSVGLLTVATEPVPSSCGEANEDSSQASLSDDHKGEHGEDGAPVPGQQLDSTVGMSSLDGTLANAAEHPSETAKQDSTSSPQLGAKKTQPGPCEITTPKRSIRDCFNYNEDSPTQPTLPKRGLFLKETQKNERKGSDRKGQVVDLKPELSRSTPSLVDPPDRSKLCLVLQSSYPSSPSAASQSYECLHKVGLGNLENIVRSHIKEISSSLGRLTDCHKEKLRLKKPHKTLAEVSLCRIPKQGGGSGKRSESTGSSAGPSMVSPGAPKATMRPETDSASTASGGLCHQRNRSGQLPVQSKASSSPPCSHSSESSLGSDSIKSPVPLLSKNKSQKSSPPAPCHATQNGQVVEAWYGSDEYLALPSHLKQTEVLALKLESLTKLLPQKPRGETIQDIDDWELSEMNSDSEIYPTYHIKKKHTRLGTVSPSSSSDIASSLGESIESGPLSDILSDEDLCLPLSSVKKFTDEKSERPSSSEKNESHSATRSALIQKLMHDIQHQENYEAIWERIEGFVNKLDEFIQWLNEAMETTENWTPPKAETDSLRLYLETHLSFKLNVDSHCALKEAVEEEGHQLLELVVSHKAGLKDTLRMIASQWKELQRQIKRQHSWILRALDTIKAEILATDVSVEDEEGTGSPKAEVQLCHLETQRDAVEQMSLKLYSEQYTSGSKRKEEFANMSKAHAEGSNGLLDFDSEYQELWDWLIDMESLVMDSHDLMMSEEQQQHLYKRYSVEMSIRHLKKSELLSKVEALKKGGLSLPDDILEKVDSINEKWELLGKTLREKIQDTIAGHSGSGPRDLLSPESGSLVRQLEVRIKELKRWLRDTELFIFNSCLRQEKEGTSAEKQLQYFKSLCREIKQRRRGVASILRLCQHLLDDRDTCNLNADHQPMQLIIVNLERRWEAIVMQAVQWQTRLQKKMGKESETLNVIDPGLMDLNGMSEDALEWDETDISNKLISVHEESNDLDQDPEPMLPAVKLEETHHKDSGYEEEAGDCGGSPYTSNITAPSSPHIYQVYSLHNVELHEDSHTPFLKSSPKFTGTTQPTVLTKSLSKDSSFSSTKSLPDLLGGSGLVRPYSCHSGDLSQNSGSESGIVSEGDNEMPTNSDMSLFSMVDGSPSNPETEHPDPQMGDAANVLEQKFKDNGESIKLSSVSRASVSPVGCVNGKAGDLNSVTKHTADCLGEELQGKHDVFTFYDYSYLQGSKLKLPMIMKQPQSEKAHVEDPLLGGFYFDKKSCKAKHQASESQPDAPPHERILASAPHEMGRSAYKSSDIEKTFTGIQSARQLSLLSRSSSVESLSPGGDLFGLGIFKNGSDSLQRSTSLESWLTSYKSNEDLFSCHSSGDISVSSGSVGELSKRTLDLLNRLENIQSPSEQKIKRSVSDMTLQSSSQKMPFAGQMSLDVASSINEDSPASLTELSSSDELSLCSEDIVLHKNKIPESNASFRKRLNRSVADESDVNVSMIVNVSCTSACTDDEDDSDLLSSSTLTLTEEELCLKDEDDDSSIATDDEIYEESNLMSGLDYIKNELQTWIRPKLSLTREKKRSGVTDEIKVNKDGGGNEKANPSDTLDIEALLNGSIRCLSENNGNGKTPPRTHGSGTKGENKKSTYDVSKDPHVADMENGNIESTPEREREKPQGLPEVSENLASNVKTISESELSEYEAVMDGSEDSSVARKEFCPPNDRHPPQMGPKLQHPENQSGDCKPVQNPCPGLLSEAGVGSRQDSNGLKSLPNDAPSGARKPAGCCLLEQNETEESASISSNASCCNCKPDVFHQKDDEDCSVHDFVKEIIDMASTALKSKSQPESEVAAPTSLTQIKEKVLEHSHRPIHLRKGDFYSYLSLSSHDSDCGEVTNYIDEKSSTPLPPDAVDSGLDDKEDMDCFFEACVEDEPVNEEAGLPGALPNESAIEDGAEQKSEQKTASSPVLSDKTDLVPLSGLSPQKGADDAKEGDDVSHTSQGCAESTEPTTPSGKANAEGRSRMQGVSATPEENAASAKPKIQAFSLNAKQPKGKVAMRYPSPQTLTCKEKLVNFHEDRHSNMHR", "length": 2314 }, "evidence": [ { "id": "HGNC:376", "url": "https://alliancegenome.org/gene/HGNC:376#orthology", "database": "AGR" }, { "id": "MGI:3050566", "url": "https://alliancegenome.org/gene/MGI:3050566#orthology", "database": "AGR" }, { "id": "RGD:69412", "url": "https://alliancegenome.org/gene/RGD:69412#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120207-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120207-2#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "F1QAQ3", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3" } ], "pmid": "" }, { "name": "nuclear membrane", "id": "GO:0031965", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031965", "evidence": [ { "database": "UniProtKB", "id": "F1QAQ3", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3" } ], "pmid": "" }, { "name": "sarcoplasmic reticulum", "id": "GO:0016529", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016529", "evidence": [ { "database": "UniProtKB", "id": "F1QAQ3", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of relaxation of cardiac muscle", "id": "GO:1901897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1901897", "evidence": [ { "database": "UniProtKB", "id": "F1QAQ3", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3" } ], "pmid": "" }, { "name": "regulation of membrane repolarization", "id": "GO:0060306", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0060306", "evidence": [ { "database": "UniProtKB", "id": "F1QAQ3", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3" } ], "pmid": "" }, { "name": "regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum", "id": "GO:0010880", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010880", "evidence": [ { "database": "UniProtKB", "id": "F1QAQ3", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cytoskeleton-nuclear membrane anchor activity", "id": "GO:0140444", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140444", "evidence": [ { "database": "UniProtKB", "id": "F1QAQ3", "url": "https://www.uniprot.org/uniprotkb/F1QAQ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1481, "end_pos": 1483, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1517, "end_pos": 1519, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1542, "end_pos": 1544, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1662, "end_pos": 1664, "annotation": "n_glycosylation_sequon" }, { "start_pos": 179, "end_pos": 181, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2019, "end_pos": 2021, "annotation": "n_glycosylation_sequon" }, { "start_pos": 499, "end_pos": 501, "annotation": "n_glycosylation_sequon" }, { "start_pos": 624, "end_pos": 626, "annotation": "n_glycosylation_sequon" }, { "start_pos": 686, "end_pos": 688, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 21 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1481, "end_pos": 1483 }, { "start_pos": 1517, "end_pos": 1519 }, { "start_pos": 1542, "end_pos": 1544 }, { "start_pos": 1662, "end_pos": 1664 }, { "start_pos": 179, "end_pos": 181 }, { "start_pos": 2019, "end_pos": 2021 }, { "start_pos": 499, "end_pos": 501 }, { "start_pos": 624, "end_pos": 626 }, { "start_pos": 686, "end_pos": 688 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0S8J0-1", "uniprot_ac": "B0S8J0", "uniprot_id": "B0S8J0_DANRE", "mass": { "chemical_mass": 21509.0, "monoisotopic_mass": 21509.0 }, "refseq": { "ac": "NP_001121801", "name": "ly6/PLAUR domain-containing protein 6B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121801" }, "gene_names": [ { "name": "lypd6b", "type": "recommended", "evidence": [ { "id": "B0S8J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S8J0" } ] }, { "name": "lypd6b", "type": "synonym", "evidence": [ { "id": "NP_001121801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121801" } ] }, { "name": "zgc:113301", "type": "synonym", "evidence": [ { "id": "NP_001121801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121801" }, { "id": "B0S8J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S8J0" } ] } ], "protein_names": [ { "name": "CHCHD4", "type": "synonym", "evidence": [ { "id": "NP_001121801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121801" } ] }, { "name": "Ly6/PLAUR domain-containing protein 6B", "type": "synonym", "evidence": [ { "id": "B0S8J0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S8J0/entry#names_and_taxonomy" } ] }, { "name": "ly6/PLAUR domain-containing protein 6B", "type": "synonym", "evidence": [ { "id": "NP_001121801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121801" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC095889.1, CK698652.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN06645146 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000009.1. On or before Jun 7, 2016 this sequence version replaced NP_001018559.1, XP_701922.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001121801", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121801" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S8J0", "url": "https://www.uniprot.org/uniprotkb/B0S8J0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "lypd6b", "url": "https://www.uniprot.org/uniprotkb/B0S8J0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050522-38", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-38", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077643", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077643", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd23626", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd23626", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "554606", "url": "https://www.ncbi.nlm.nih.gov/gene/554606", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039457", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039457", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:554606", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:554606", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FVGCHRH", "url": "https://omabrowser.org/oma/group/FVGCHRH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A2R8PW90", "url": "https://www.orthodb.org/?gene=A0A2R8PW90", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "B0S8J0", "url": "https://www.orthodb.org/?gene=B0S8J0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31171", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31171", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31171:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31171:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF16975", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16975", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001121801", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121801", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A2R8PW90", "url": "https://www.uniprot.org/uniprotkb/A0A2R8PW90", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2R8PW90-1", "url": "https://www.uniprot.org/uniprotkb/A0A2R8PW90-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S8J0", "url": "https://www.uniprot.org/uniprotkb/B0S8J0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S8J0-1", "url": "https://www.uniprot.org/uniprotkb/B0S8J0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050522-38", "url": "https://zfin.org/ZDB-GENE-050522-38", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNRQLFQHMFYAADALPGVTNSVSNMAVSNFVSVLVLLLVNLVTSENIDFYNLRPAIEATPYPKSFKCFTCEQASDNYSCNRWAEDVWCPQNTQYCMTIHHFNHHGKTKFVTKRCAVRDECRLAGCRHHKNTHHECVSCCEGMVCNVELPTNHSNAVFAQRRAHSSASATFRSWHSVILLIPALSGLMPL", "length": 190, "header": "tr|B0S8J0-1|B0S8J0_DANRE Isoform 1 of Ly6/PLAUR domain-containing protein 6B OS=Danio rerio OX=7955 GN=lypd6b PE=4 SV=1 CANONICAL=B0S8J0-1" }, "isoforms": [ { "isoform_ac": "A0A2R8PW90-1", "url": "https://www.uniprot.org/uniprotkb/B0S8J0/entry#A0A2R8PW90-1", "sequence": { "sequence": "MAVSNFVSVLVLLLVNLVTSENIDFYNLRPAIEATPYPKSFKCFTCEQASDNYSCNRWAEDVWCPQNTQYCMTIHHFNHHGKTKFVTKRCAVRDECRLAGCRHHKNTHHECVSCCEGMVCNVELPTNHSNAVFAQRRAHSSASATFRSWHSVILLIPALSGLMPL", "length": 165, "header": "tr|A0A2R8PW90-1|B0S8J0_DANRE Computationally mapped isoform of Ly6/PLAUR domain-containing protein 6B OS=Danio rerio OX=7955 GN=lypd6b PE=4 SV=1 CANONICAL=B0S8J0-1" }, "locus": {} }, { "isoform_ac": "B0S8J0-1", "url": "https://www.uniprot.org/uniprotkb/B0S8J0/entry#B0S8J0-1", "sequence": { "sequence": "MNRQLFQHMFYAADALPGVTNSVSNMAVSNFVSVLVLLLVNLVTSENIDFYNLRPAIEATPYPKSFKCFTCEQASDNYSCNRWAEDVWCPQNTQYCMTIHHFNHHGKTKFVTKRCAVRDECRLAGCRHHKNTHHECVSCCEGMVCNVELPTNHSNAVFAQRRAHSSASATFRSWHSVILLIPALSGLMPL", "length": 190, "header": "tr|B0S8J0-1|B0S8J0_DANRE Isoform 1 of Ly6/PLAUR domain-containing protein 6B OS=Danio rerio OX=7955 GN=lypd6b PE=4 SV=1 CANONICAL=B0S8J0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome.", "journal": "PLoS ONE", "date": "2006", "authors": "Pickart Michael A, Klee Eric W, Nielsen Aubrey L, Sivasubbu Sridhar, Mendenhall Eric M, Bill Brent R, Chen Eleanor, Eckfeldt Craig E, Knowlton Michelle, Robu Mara E, Larson Jon D, Deng Yun, Schimmenti Lisa A, Ellis Lynda B M, Verfaillie Catherine M, Hammerschmidt Matthias, Farber Steven A, Ekker Stephen C", "evidence": [ { "database": "UniProtKB", "id": "B0S8J0", "url": "https://www.uniprot.org/uniprotkb/B0S8J0" } ], "reference": [ { "type": "PubMed", "id": "17218990", "url": "https://glygen.org/publication/PubMed/17218990" } ] }, { "title": "Identification and expression of a novel member of Ly-6 superfamily in zebrafish Denio rerio.", "journal": "Dev. Genes Evol.", "date": "2012", "authors": "Ji Dongrui, Liu Pei, Wang Fei, Zhang Shicui, Li Hongyan", "evidence": [ { "database": "UniProtKB", "id": "B0S8J0", "url": "https://www.uniprot.org/uniprotkb/B0S8J0" } ], "reference": [ { "type": "PubMed", "id": "22415300", "url": "https://glygen.org/publication/PubMed/22415300" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0S8J0", "url": "https://www.uniprot.org/uniprotkb/B0S8J0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B0S8J0", "url": "https://www.uniprot.org/uniprotkb/B0S8J0" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:554606", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:554606", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZUF1-1", "protein_name": "Ly6/Plaur domain containing 6B", "gene_name": "Lypd6b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLLCHILAVTILQILVISENWVFAKNINFYNVRPPLDPTPFPNSFKCFTCENAGDNYNCNRWAEDKWCPQETQYCLTVHHFTSHGRSTSITKKCASKNECHFVGCRHSRDSEHTECRSCCEGMICNVELPTNHTNAVFAVMHAQRTSGSSVSNVPRSYLPVLAWLFMLPLL", "length": 172 }, "evidence": [ { "id": "HGNC:27018", "url": "https://alliancegenome.org/gene/HGNC:27018#orthology", "database": "AGR" }, { "id": "MGI:1919147", "url": "https://alliancegenome.org/gene/MGI:1919147#orthology", "database": "AGR" }, { "id": "RGD:1562767", "url": "https://alliancegenome.org/gene/RGD:1562767#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-38", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-38#orthology", "database": "AGR" }, { "id": "B0S8J0", "url": "https://omabrowser.org/oma/group/B0S8J0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NI32-1", "protein_name": "Ly6/PLAUR domain-containing protein 6B", "gene_name": "LYPD6B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLYKSSDRPAHKVSMLLLCHALAIAVVQIVIFSESWAFAKNINFYNVRPPLDPTPFPNSFKCFTCENAGDNYNCNRWAEDKWCPQNTQYCLTVHHFTSHGRSTSITKKCASRSECHFVGCHHSRDSEHTECRSCCEGMICNVELPTNHTNAVFAVMHAQRTSGSSAPTLYLPVLAWVFVLPLL", "length": 183 }, "evidence": [ { "id": "HGNC:27018", "url": "https://alliancegenome.org/gene/HGNC:27018#orthology", "database": "AGR" }, { "id": "MGI:1919147", "url": "https://alliancegenome.org/gene/MGI:1919147#orthology", "database": "AGR" }, { "id": "RGD:1562767", "url": "https://alliancegenome.org/gene/RGD:1562767#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050522-38", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050522-38#orthology", "database": "AGR" }, { "id": "B0S8J0", "url": "https://omabrowser.org/oma/group/B0S8J0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D7F2-2", "protein_name": "Ly6/PLAUR domain-containing protein 6B", "gene_name": "Lypd6b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLLCHILAVTILQILIISENWVFAKNINFYNVRPPLDPTPFPNSFKCFTCENAGDNYNCNRWAEDKWCPQDTQYCLTVHHFTSHGRSTSITKKCASKNECHFVGCRHSRDSEHTECRSCCEGMICNVELPTNHTNAVFAVMHAQRTSGSSVSSVPSPYLLVLAWLFMLPLL", "length": 172 }, "evidence": [ { "id": "HGNC:27018", "url": "https://alliancegenome.org/gene/HGNC:27018#orthology", "database": "AGR" }, { "id": "MGI:1919147", "url": 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"database": "UniProtKB", "id": "B0S8J0", "url": "https://www.uniprot.org/uniprotkb/B0S8J0" } ], "pmid": "" }, { "name": "side of membrane", "id": "GO:0098552", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0098552", "evidence": [ { "database": "UniProtKB", "id": "B0S8J0", "url": "https://www.uniprot.org/uniprotkb/B0S8J0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 152, "end_pos": 154, "annotation": "n_glycosylation_sequon" }, { "start_pos": 77, "end_pos": 79, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 152, "end_pos": 154 }, { "start_pos": 77, "end_pos": 79 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7FBD4-1", "uniprot_ac": "E7FBD4", "uniprot_id": "E7FBD4_DANRE", "mass": { "chemical_mass": 42868.0, "monoisotopic_mass": 42868.0 }, "refseq": { "ac": "XP_002664815", "name": "fasciculation and elongation protein zeta-2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664815" }, "gene_names": [ { "name": "fez2a", "type": "recommended", "evidence": [ { "id": "E7FBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FBD4" } ] }, { "name": "fez2a", "type": "synonym", "evidence": [ { "id": "XP_002664815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664815" } ] } ], "protein_names": [ { "name": "Fasciculation and elongation protein zeta-2 isoform X1", "type": "synonym", "evidence": [ { "id": "E7FBD4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FBD4/entry#names_and_taxonomy" } ] }, { "name": "fasciculation and elongation protein zeta-2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002664815", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664815" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002664815.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_002664815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664815" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FBD4", "url": "https://www.uniprot.org/uniprotkb/E7FBD4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fez2a", "url": "https://www.uniprot.org/uniprotkb/E7FBD4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110411-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-17", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000073784", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000073784", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100334565", "url": "https://www.ncbi.nlm.nih.gov/gene/100334565", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100334565", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100334565", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "METNIRR", "url": "https://omabrowser.org/oma/group/METNIRR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A2R8Q8U4", "url": "https://www.orthodb.org/?gene=A0A2R8Q8U4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FBD4", "url": "https://www.orthodb.org/?gene=E7FBD4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12394", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12394", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12394:SF11", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12394:SF11", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07763", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07763", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_002664815", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664815", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A2R8Q8U4", "url": "https://www.uniprot.org/uniprotkb/A0A2R8Q8U4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2R8Q8U4-1", "url": "https://www.uniprot.org/uniprotkb/A0A2R8Q8U4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FBD4", "url": "https://www.uniprot.org/uniprotkb/E7FBD4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FBD4-1", "url": "https://www.uniprot.org/uniprotkb/E7FBD4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110411-17", "url": "https://zfin.org/ZDB-GENE-110411-17", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAEPSSRREDEEWQDFNEFKGGTGRNLDVSAEETRLSLLLLLDELSDAESALQTGAFTSTHFDENLQLCFQDVHSKTDAGNELTSLNEETTLKCDEIWSALTDNYGHVMPVDWSQSRVRSLHLSTLSLDDRARLESVNLDVSDDEELRDQMDMHSIIVSCINEEPLLTAEQVIEEIEELMQESPEVESEQNVSHSGVSFISQKRSHSSQIYEDRVRLMSVLELNDELEDVETAIRGYSEELIHHLATRDELEFEKEVKNSFISVLIDVQNRQKLQREMLKKKRKVRSTSGSERLPSSRFSMEGISTAIQNGFRHTFGNGGGEKQYVTTVIPYERRDGPPSVQDLQIFTKILEAMRDDSDKVPSLLTDYILKVLCPT", "length": 376, "header": "tr|E7FBD4-1|E7FBD4_DANRE Isoform 1 of Fasciculation and elongation protein zeta-2 isoform X1 OS=Danio rerio OX=7955 GN=fez2a PE=3 SV=1 CANONICAL=E7FBD4-1" }, "isoforms": [ { "isoform_ac": "A0A2R8Q8U4-1", "url": "https://www.uniprot.org/uniprotkb/E7FBD4/entry#A0A2R8Q8U4-1", "sequence": { "sequence": "MAEPSSRREDEEWQDFNEFKGGTGRNLDVSAEETRLSLLLLLDELSDAESALQTGAFTSTHFDENLQLCFQDVHSKTDAGNELTSLNEETTLKCDEIWSALTDNYGHVMPVDWSQSRVRSLHLSTLSLDDRARLESVNLDVSDDEELRDQMDMHSIIVSCINEEPLLTAEQVIEEIEELMQESPEVESEQNVSHSGVSFISQKRSHSSQIYEDRVRLMSVLELNDELEDVETAIRGYSEELIHHLATRDELEFEKEVKNSFISVLIDVQNRQKLQREMLKKKRKVRSTSGSERLPSSYVTTVIPYERRDGPPSVQDLQIFTKILEAMRDDSDKVPSLLTDYILKVLCPT", "length": 349, "header": "tr|A0A2R8Q8U4-1|E7FBD4_DANRE Computationally mapped isoform of Fasciculation and elongation protein zeta-2 isoform X1 OS=Danio rerio OX=7955 GN=fez2a PE=3 SV=1 CANONICAL=E7FBD4-1" }, "locus": {} }, { "isoform_ac": "E7FBD4-1", "url": "https://www.uniprot.org/uniprotkb/E7FBD4/entry#E7FBD4-1", "sequence": { "sequence": "MAEPSSRREDEEWQDFNEFKGGTGRNLDVSAEETRLSLLLLLDELSDAESALQTGAFTSTHFDENLQLCFQDVHSKTDAGNELTSLNEETTLKCDEIWSALTDNYGHVMPVDWSQSRVRSLHLSTLSLDDRARLESVNLDVSDDEELRDQMDMHSIIVSCINEEPLLTAEQVIEEIEELMQESPEVESEQNVSHSGVSFISQKRSHSSQIYEDRVRLMSVLELNDELEDVETAIRGYSEELIHHLATRDELEFEKEVKNSFISVLIDVQNRQKLQREMLKKKRKVRSTSGSERLPSSRFSMEGISTAIQNGFRHTFGNGGGEKQYVTTVIPYERRDGPPSVQDLQIFTKILEAMRDDSDKVPSLLTDYILKVLCPT", "length": 376, "header": "tr|E7FBD4-1|E7FBD4_DANRE Isoform 1 of Fasciculation and elongation protein zeta-2 isoform X1 OS=Danio rerio OX=7955 GN=fez2a PE=3 SV=1 CANONICAL=E7FBD4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100334565", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100334565", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P97578-1", "protein_name": "Fasciculation and elongation protein zeta-2", "gene_name": "Fez2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAADGDWQDFYEFQEPAGSVRDQENCNASPEAGAGAHAGGDSFPALASSLEEKLSLCFRPTSDADPPRAAVRPITERSLLQGDEIWNALTDNYGNVMPVDWKSSHTRTLHLLTLNLTEKGMSDGLPFDTSDEEELREQLDMHSIIVSCVNEEPLFTADQVIEEIEEMMQESPDLEDDETPTQSDRLSMLSQEIQTLKSSSMSSCEERVKRLSVSELNELLEEIETAIKEYSEELVQQLALRDELEFEKEVENSFISALIEVQNKQKEHKETAKKKKKLKNGSSQNGRNERSHMPGTRFSMEGISNVIQNGLRHTFGNSGGEKQYLTTVIPYEKKNGPPSVEDLQILTKILHAMKEDSEKVPSLLTDYILKVLCPT", "length": 375 }, "evidence": [ { "id": "HGNC:3660", "url": "https://alliancegenome.org/gene/HGNC:3660#orthology", "database": "AGR" }, { "id": "MGI:2675856", "url": "https://alliancegenome.org/gene/MGI:2675856#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6TYB5-1", "protein_name": "Fasciculation and elongation protein zeta-2", "gene_name": "Fez2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAADGDWQDFYEFQEPAGSVQEQENCNASPEAGAGAHAGGDSFPALASSLEEKLSLCFRPTSEAEPPRAAVRPITECSLLQGDEIWNALTDNYGNVMPVDWKSSHTRTLHLLTLNLSEKGMNDGLLFDASDEEELREQLDMHSIIVSCVNEEPLFTADQVIEEIEEMMQESPDPEDDETPTQSDRLSMLSQEIQTLKRSSMSSYEERVKRLSVSELNELLEEIEAAIKQYSEELVQQLALRDELEFEKEVENSFISALIEVQNKQKEHKETAKKKKKLKSGSSQNGRSERSHMPGTYLTTVIPYEKKSGPPSVEDLQILTKILHAMKEDSEKVPSLLTDYILKVLCPT", "length": 348 }, "evidence": [ { "id": "HGNC:3660", "url": "https://alliancegenome.org/gene/HGNC:3660#orthology", "database": "AGR" }, { "id": "MGI:2675856", "url": "https://alliancegenome.org/gene/MGI:2675856#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110411-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-17#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHY8-1", "protein_name": "Fasciculation and elongation protein zeta-2", "gene_name": "FEZ2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAADGDWQDFYEFQEPARSLLDQENCNASPEPGAEAGAEAGGGADGFPAPACSLEEKLSLCFRPSDPGAEPPRTAVRPITERSLLQGDEIWNALTDNYGNVMPVDWKSSHTRTLHLLTLNLSEKGVSDSLLFDTSDDEELREQLDMHSIIVSCVNDEPLFTADQVIEEIEEMMQESPDPEDDETPTQSDRLSMLSQEIQTLKRSSTGSYEERVKRLSVSELNEILEEIETAIKEYSEELVQQLALRDELEFEKEVKNSFISVLIEVQNKQKEHKETAKKKKKLKNGSSQNGKNERSHMPGTYLTTVIPYEKKNGPPSVEDLQILTKILRAMKEDSEKVPSLLTDYILKVLCPT", "length": 353 }, "evidence": [ { "id": "HGNC:3660", "url": "https://alliancegenome.org/gene/HGNC:3660#orthology", "database": "AGR" }, { "id": "MGI:2675856", "url": "https://alliancegenome.org/gene/MGI:2675856#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110411-17", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110411-17#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W525-1", "protein_name": "Uncoordinated 76, isoform B", "gene_name": "Unc-76", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MRDLGTKMAELKFEAPLAKFEETDEWGGCDFISSQNAINDTLNLNLKDSSAGGKPDATKLRLLEDAVRDAHVSKNGGGVVGGGAGSISPNCNTLQGGSLIEIGLSDVGLVPGEGAGVGLDGLEKRSLAVGDHVDNFTETFGGSLEDLVNTFDEKITKCFGNYEENVEELAPVQVRSQEEIMNECQMWWTITGNFGNILPIDWSKSYTRQMHMPTLNLGQNHTKQQQQNRNQQQQLHNQSHQAYPHTNGLGSGSGSGLDAQTPGDEFNDLTSEDEAVANDLDMHALILNGLNGDMDDQPIKTVEEVIKEIDDIMDEAESPLDEPETCDSEVIEKAREVLGAPLYAEKLQYLTTTQLNELYMEMEVLIQELSETLINELALRDELEFEKELKNSFISLLLAVQNKRRQYHVEKKRGKFQGPEPKYLTTVIPYHLENGTPNNQSLQVLIKILKAINEDSPTVPALLTDYILKVLCPT", "length": 474 }, "evidence": [ { "id": "HGNC:3660", "url": "https://alliancegenome.org/gene/HGNC:3660#orthology", "database": "AGR" }, { "id": "MGI:2675856", "url": "https://alliancegenome.org/gene/MGI:2675856#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7FBD4", "url": "https://www.uniprot.org/uniprotkb/E7FBD4" } ], "pmid": "" }, { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "E7FBD4", "url": "https://www.uniprot.org/uniprotkb/E7FBD4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 191, "end_pos": 193, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 191, "end_pos": 193 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F6F0-1", "uniprot_ac": "E7F6F0", "uniprot_id": "E7F6F0_DANRE", "mass": { "chemical_mass": 33727.0, "monoisotopic_mass": 33727.0 }, "refseq": { "ac": "XP_005166509", "name": "protein BEAN1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166509" }, "gene_names": [ { "name": "bean1", "type": "recommended", "evidence": [ { "id": "E7F6F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6F0" } ] }, { "name": "bean1", "type": "synonym", "evidence": [ { "id": "XP_005166509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166509" } ] } ], "protein_names": [ { "name": "Protein BEAN1 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F6F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6F0/entry#names_and_taxonomy" } ] }, { "name": "protein BEAN1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005166509", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166509" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133182) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005166509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166509" } ] } ], "disease": [ { "disease_id": "DOID:0050980", "recommended_name": { "id": "DOID:0050980", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050980", "name": "spinocerebellar ataxia 31", "description": "An autosomal dominant cerebellar ataxia that is characterized by late-onset ataxia, dysarthria and horizontal nystagmus, has_material_basis_in repeat expansion mutation in the BEAN1 gene." }, "synonyms": [ { "id": "MONDO:0007296", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007296", "name": "spinocerebellar ataxia type 31", "description": "Spinocerebellar ataxia type 31 (SCA31) is a very rare subtype of autosomal dominant cerebellar ataxia type III (ADCA type III) characterized by the late-onset of cerebral ataxia, dysarthria and horizontal gaze nystagmus, and that is occasionally accompanied by pyramidal signs, tremor, decreased vibration sense and hearing difficulties." }, { "id": "MONDO:0007296", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007296", "name": "SCA31", "description": "" }, { "id": "MONDO:0007296", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007296", "name": "spinocerebellar ataxia type 31", "description": "" }, { "id": "MONDO:0007296", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007296", "name": "spinocerebellar ataxia 16q22-linked", "description": "" }, { "id": "MONDO:0007296", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007296", "name": "spinocerebellar ataxia 31", "description": "" }, { "id": "MIM:117210", "resource": "MIM", "url": "https://www.omim.org/entry/117210", "name": "Spinocerebellar ataxia 31", "description": "Spinocerebellar ataxia 31" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050980", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050980" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F6F0", "url": "https://www.uniprot.org/uniprotkb/E7F6F0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "bean1", "url": "https://www.uniprot.org/uniprotkb/E7F6F0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141216-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141216-52", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000087413", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000087413", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101885923", "url": "https://www.ncbi.nlm.nih.gov/gene/101885923", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039352", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039352", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR060206", "url": "https://www.ebi.ac.uk/interpro/entry/IPR060206", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885923", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885923", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HRIRYSC", "url": "https://omabrowser.org/oma/group/HRIRYSC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A2R8RPK8", "url": "https://www.orthodb.org/?gene=A0A2R8RPK8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F6F0", "url": "https://www.orthodb.org/?gene=E7F6F0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36464", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36464", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36464:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36464:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF28336", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28336", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005166509", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005166509", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A2R8RPK8", "url": "https://www.uniprot.org/uniprotkb/A0A2R8RPK8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A2R8RPK8-1", "url": "https://www.uniprot.org/uniprotkb/A0A2R8RPK8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F6F0", "url": "https://www.uniprot.org/uniprotkb/E7F6F0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F6F0-1", "url": "https://www.uniprot.org/uniprotkb/E7F6F0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-141216-52", "url": "https://zfin.org/ZDB-GENE-141216-52", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGLFSSLQAVLLHSPLVFTNSDIIKTSQIYSKAYENTIFLCKKEKVKVGTCLVNRLRCYYRKDCGREYMLMKLICSVSSNQSSHAPEYPDCQEGGNEASLLVSPLVVAGIVIGLVLFLSCVTIIVGSLRKDSRLRNPHLRASYAPDGLSYGGSIGELRSTCVEDFPPAFDFDSYVETLSQVNVMYPDSPPHYDECVGQGTQIYVPTDDPPPYSLTDPCRDQYMEDLPAGASWVSASGSSRYPSRLQNFRHQPVASISLSALPLDEAPPYEAVMSEQNQPLPLMPLDLLKHTTADSSAQDSVSHRIL", "length": 306, "header": "tr|E7F6F0-1|E7F6F0_DANRE Isoform 1 of Protein BEAN1 isoform X1 OS=Danio rerio OX=7955 GN=bean1 PE=4 SV=1 CANONICAL=E7F6F0-1" }, "isoforms": [ { "isoform_ac": "A0A2R8RPK8-1", "url": "https://www.uniprot.org/uniprotkb/E7F6F0/entry#A0A2R8RPK8-1", "sequence": { "sequence": "MGLFSSLQADENTIFLCKKEKVKVGTCLVNRLRCYYRKDCGREYMLMKLICSVSSNQSSHAPEYPDCQEGGNEASLLVSPLVVAGIVIGLVLFLSCVTIIVGSLRKDSRLRNPHLRASYAPDGLSYGGSIGELRSTCVEDFPPAFDFDSYVETLSQVNVMYPDSPPHYDECVGQGTQIYVPTDDPPPYSLTDPCRDQYMEDLPAGASWVSASGSSRYPSRLQNFRHQPVASISLSALPLDEAPPYEAVMSEQNQPLPLMPLDLLKHTTADSSAQDSVSHRIL", "length": 282, "header": "tr|A0A2R8RPK8-1|E7F6F0_DANRE Computationally mapped isoform of Protein BEAN1 isoform X1 OS=Danio rerio OX=7955 GN=bean1 PE=4 SV=1 CANONICAL=E7F6F0-1" }, "locus": {} }, { "isoform_ac": "E7F6F0-1", "url": "https://www.uniprot.org/uniprotkb/E7F6F0/entry#E7F6F0-1", "sequence": { "sequence": "MGLFSSLQAVLLHSPLVFTNSDIIKTSQIYSKAYENTIFLCKKEKVKVGTCLVNRLRCYYRKDCGREYMLMKLICSVSSNQSSHAPEYPDCQEGGNEASLLVSPLVVAGIVIGLVLFLSCVTIIVGSLRKDSRLRNPHLRASYAPDGLSYGGSIGELRSTCVEDFPPAFDFDSYVETLSQVNVMYPDSPPHYDECVGQGTQIYVPTDDPPPYSLTDPCRDQYMEDLPAGASWVSASGSSRYPSRLQNFRHQPVASISLSALPLDEAPPYEAVMSEQNQPLPLMPLDLLKHTTADSSAQDSVSHRIL", "length": 306, "header": "tr|E7F6F0-1|E7F6F0_DANRE Isoform 1 of Protein BEAN1 isoform X1 OS=Danio rerio OX=7955 GN=bean1 PE=4 SV=1 CANONICAL=E7F6F0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885923", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885923", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BEU7-1", "protein_name": "Brain expressed associated with NEDD4 1", "gene_name": "BEAN1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSFKRPCPSRYNRTSYFYPTFSESSEHSHLLVSPVLVASAVIGVVIILSCITIIVGSIRRDRQARLQRHRHRPRRRHHHHHRRRRRRRHRESEHGYVSDGHVYSRSSHRLRYACSPAEDWPPPLDLSSDGDVDATVLRELYPDSPPGYEECVGPGATQLYIPTDAPPPYSLTDSCPALDGALDAGSGRSPGRHQQRPQGPSGLRTVSMDTLPPYEAVCGPSPPSGLLPLPGPEPGPRGSHGSPAPTRAPASGPERIL", "length": 257 }, "evidence": [ { "id": "E7F6F0", "url": "https://omabrowser.org/oma/group/E7F6F0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0XUB6-1", "protein_name": "Brain expressed associated with NEDD4 1", "gene_name": "BEAN1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "METATAAAGWVLFFHLPLISASSIRIGIGSNSSLYEQSILPCKKEELQCGTGLCLSNWLRCRYRKDCGRDYMSIQLTCSKVHLNQSSPTSELPSYSENGSDASLLVSPLLVAGVVIGLVLFLSCVTIIVGSLRKDGRLRHPHQRRDTAYAPDGFSYSGSFGELRSTCMEEFPPGFDFGSYLDTLSQVNIMYPDSPPRYDECVGPGATQIYIPTDDPPPYSLTDPCQRSEIPTNISLEEQEEAAGTAGQAAHHATRLQGWQQPTPSISLSPLPTEAAPRYEAVVCEHNIPIPLVPVEVLKNSPADYQTILSQIL", "length": 313 }, "evidence": [ { "id": "E7F6F0", "url": "https://omabrowser.org/oma/group/E7F6F0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LPW7-1", "protein_name": "Brain expressed, associated with NEDD4, 1", "gene_name": "Bean1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "PGPWRRRAETPEPRRRRGGPERVTVARAAARGRPGRGCCCCRAGQGRTRETAGGGGSPGNRGRGSVLPGPAGAPRPCTHSRPRRSGGTPQSSPSGGIRAGAGARVGPELEPKLEPALRRTERSAAAKPIARYNRTSYFYPTTFSESSEHSHLLVSPVLVASAVIGVVITLSCITIIVGSIRRDRQARIQRHHHRHRRHHHHHRHRRRRHREYEQDHASGGHTHSHSSHRMPYACSPAEDWPPPLDISSEGEVDVTVLRELYPDSPPGYEECVGPGATQLYVPTDAPPPYSMTDSCLMLNGALDSNSGHSHSHHQQEQRTHGQSGLHTVSMDTLPPYEAVCGGGSPSDLLPLPGPEPRPSNSQGSLTPTQAPTPSPERIV", "length": 379 }, "evidence": [ { "id": "MGI:1929597", "url": "https://alliancegenome.org/gene/MGI:1929597#orthology", "database": "AGR" }, { "id": "HGNC:24160", "url": "https://alliancegenome.org/gene/HGNC:24160#orthology", "database": "AGR" }, { "id": "E7F6F0", "url": "https://omabrowser.org/oma/group/E7F6F0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3B7T3-1", "protein_name": "Protein BEAN1", "gene_name": "BEAN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSFKRPCPLARYNRTSYFYPTFSESSEHSHLLVSPVLVASAVIGVVIILSCITIIVGSIRRDRQARLQRHRHRHHRHHHHHHHHRRRRHREYEHGYVSDEHTYSRSSRRMRYACSSSEDWPPPLDISSDGDVDATVLRELYPDSPPGYEECVGPGATQLYVPTDAPPPYSLTDSCPTLDGTSDSGSGHSPGRHQQEQRTPAQGGLHTVSMDTLPPYEAVCGAGPPSGLLPLPGPDPGPRGSQGSPTPTRAPASGPERIV", "length": 259 }, "evidence": [ { "id": "MGI:1929597", "url": "https://alliancegenome.org/gene/MGI:1929597#orthology", "database": "AGR" }, { "id": "HGNC:24160", "url": "https://alliancegenome.org/gene/HGNC:24160#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141216-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141216-52#orthology", "database": "AGR" }, { "id": "E7F6F0", "url": "https://omabrowser.org/oma/group/E7F6F0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9EQG5-1", "protein_name": "Protein BEAN1", "gene_name": "Bean1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSFKRPCPLARYNRTSYFYPTTFSESSEHSHLLVSPVLVASAVIGVVITLSCITIIVGSIRRDRQARIQRHHHRHRRHHHHHRHRRRRHREYASGGHTHSRSSPRMPYACSPAEDWPPPLDVSSEGDVDVTVLWELYPDSPPGYEECMGPGATQLYVPTDAPPPYSMTDSCPRLNGALDSDSGQSRSHRQQEQRTQGQSRLHTVSMDTLPPYEAVCGTGSPSDLLPLPGPEPWPSNSQGSPIPTQAPMPSPERIV", "length": 255 }, "evidence": [ { "id": "MGI:1929597", "url": "https://alliancegenome.org/gene/MGI:1929597#orthology", "database": "AGR" }, { "id": "HGNC:24160", "url": "https://alliancegenome.org/gene/HGNC:24160#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141216-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141216-52#orthology", "database": "AGR" }, { "id": "E7F6F0", "url": "https://omabrowser.org/oma/group/E7F6F0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F6F0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6F0" }, { "id": "PF28336", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF28336" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BEAN1 helical region", "eco_id": "ECO_0000259", "start_pos": 102, "end_pos": 132, "start_aa": "Val", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FGV0-1", "uniprot_ac": "E7FGV0", "uniprot_id": "E7FGV0_DANRE", "mass": { "chemical_mass": 56405.0, "monoisotopic_mass": 56405.0 }, "refseq": { "ac": "XP_005173412", "name": "NACHT, LRR and PYD domains-containing protein 1a allele 5 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173412" }, "gene_names": [ { "name": "si:dkeyp-97b10.3", "type": "recommended", "evidence": [ { "id": "E7FGV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FGV0" } ] }, { "name": "si:dkeyp-97b10.3", "type": "synonym", "evidence": [ { "id": "XP_005173412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173412" } ] } ], "protein_names": [ { "name": "NACHT, LRR and PYD domains-containing protein 1a allele 5 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005173412", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173412" }, { "id": "E7FGV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FGV0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005173412", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173412" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FGV0", "url": "https://www.uniprot.org/uniprotkb/E7FGV0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkeyp-97b10.3", "url": "https://www.uniprot.org/uniprotkb/E7FGV0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131121-429", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-429", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000086712", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000086712", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100007012", "url": "https://www.ncbi.nlm.nih.gov/gene/100007012", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000488", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000488", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011029", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011029", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021861", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021861", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100007012", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100007012", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M1PT13", "url": "https://www.orthodb.org/?gene=A0A8M1PT13", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FGV0", "url": "https://www.orthodb.org/?gene=E7FGV0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13265", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13265", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13265:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13265:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00531", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00531", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13553", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13553", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23679", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23679", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005173412", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173412", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M1PT13", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PT13", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1PT13-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1PT13-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T8Z5", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8Z5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T8Z5-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T8Z5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HEG2", "url": "https://www.uniprot.org/uniprotkb/A0AC58HEG2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HEG2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HEG2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FGV0", "url": "https://www.uniprot.org/uniprotkb/E7FGV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FGV0-1", "url": "https://www.uniprot.org/uniprotkb/E7FGV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131121-429", "url": "https://zfin.org/ZDB-GENE-131121-429", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVAHMADYAETKHLTDGNGDVSPSDLKDHPAESSHSSSDSTSAEESSEEDETQEEEEDRESDSNTKAGAENHSDEPLASCCEKCRALKNPKYELVTPRKMSKERLQLQLDAEGVYECSDTGLVFEVSQRVKITYCVLSWSRFSTYLTGSWKFAGPIFDVDCDPAILKSIQFPHSLCLAADKDNEVNFSVLHVKNSRGLIEPSSDHSGSHVKWTVSSLSPVGPVVQTSRSAEHHGVVQVFRELGLESSSFSFRVYLARNICSDIKDIRKAVRRANNCKNNKKYILVDKPPTCMLEENRKYRLISEPVGHITPEDMLFTPDSVEVKGYIEVFFEDSPPFKLSLTDADSGQTVWTSTIREGDCTHHVEEMPKRPTKGTKRHSSTSDDELSYKRSKKTHAVDEPDCNAVAVAPALTDQQLMRVAKHMGKEWKIVAISYLGFSNQNLEEMEAAEENATMLKFTMLERWRRRQPKGKAGVQELHNSLKDNDDVPNEVIAVLDEMLHNK", "length": 502, "header": "tr|E7FGV0-1|E7FGV0_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 1a allele 5 isoform X1 OS=Danio rerio OX=7955 GN=si:dkeyp-97b10.3 PE=4 SV=1 CANONICAL=E7FGV0-1" }, "isoforms": [ { "isoform_ac": "A0A8M1PT13-1", "url": "https://www.uniprot.org/uniprotkb/E7FGV0/entry#A0A8M1PT13-1", "sequence": { "sequence": "MVAHMADYAETKHLTDGNGDVSPSDLKDHPAESSHSSSDSTSAEESSEEDETQEEEEDRESDSNTKAGAENHSDEPLASCCEKCRALKNPKYELVTPRKMSKERLQLQLDAEGVYECSDTGLVFEVSQRVKITYCVLSWSRFSTYLTGSWKFAGPIFDVDCDPAILKSIQFPHSLCLADKDNEVNFSVLHVKNSRGLIEPSSDHSGSHVKWTVSSLSPVGPVVQTSRSAEHHGVVQVFRELGLESSSFSFRVYLARNICSDIKDIRKAVRRANNCKNNKKYILVDKPPTCMLEENRKYRLISEPVGHITPEDMLFTPDSVEVKGYIEVFFEDSPPFKLSLTDADSGQTVWTSTIREGDCTHHVEEMPKRPTKGTKRHSSTSDDELSYKRSKKTHAVDEPDCNAVAVAPALTDQQLMRVAKHMGKEWKIVAISYLGFSNQNLEEMEAAEENATMLKFTMLERWRRRQPKGKAGVQELHNSLKDNDDVPNEVIAVLDEMLHNK", "length": 501, "header": "tr|A0A8M1PT13-1|E7FGV0_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 1a allele 5 isoform X1 OS=Danio rerio OX=7955 GN=si:dkeyp-97b10.3 PE=4 SV=1 CANONICAL=E7FGV0-1" }, "locus": {} }, { "isoform_ac": "A0AB32T8Z5-1", "url": "https://www.uniprot.org/uniprotkb/E7FGV0/entry#A0AB32T8Z5-1", "sequence": { "sequence": "MSKERLQLQLDAEGVYECSDTGLVFEVSQRVKITYCVLSWSRFSTYLTGSWKFAGPIFDVDCDPAILKSIQFPHSLCLAADKDNEVNFSVLHVKNSRGLIEPSSDHSGSHVKWTVSSLSPVGPVVQTSRSAEHHGVVQVFRELGLESSSFSFRVYLARNICSDIKDIRKAVRRANNCKNNKKYILVDKPPTCMLEENRKYRLISEPVGHITPEDMLFTPDSVEVKGYIEVFFEDSPPFKLSLTDADSGQTVWTSTIREGDCTHHVEEMPKRPTKGTKRHSSTSDDELSYKRSKKTHAVDEPDCNAVAVAPALTDQQLMRVAKHMGKEWKIVAISYLGFSNQNLEEMEAAEENATMLKFTMLERWRRRQPKGKAGVQELHNSLKDNDDVPNEVIAVLDEMLHNK", "length": 403, "header": "tr|A0AB32T8Z5-1|E7FGV0_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 1a allele 5 isoform X1 OS=Danio rerio OX=7955 GN=si:dkeyp-97b10.3 PE=4 SV=1 CANONICAL=E7FGV0-1" }, "locus": {} }, { "isoform_ac": "A0AC58HEG2-1", "url": "https://www.uniprot.org/uniprotkb/E7FGV0/entry#A0AC58HEG2-1", "sequence": { "sequence": "MSKERLQLQLDAEGVYECSDTGLVFEVSQRVKITYCVLSWSRFSTYLTGSWKFAGPIFDVDCDPAILKSIQFPHSLCLADKDNEVNFSVLHVKNSRGLIEPSSDHSGSHVKWTVSSLSPVGPVVQTSRSAEHHGVVQVFRELGLESSSFSFRVYLARNICSDIKDIRKAVRRANNCKNNKKYILVDKPPTCMLEENRKYRLISEPVGHITPEDMLFTPDSVEVKGYIEVFFEDSPPFKLSLTDADSGQTVWTSTIREGDCTHHVEEMPKRPTKGTKRHSSTSDDELSYKRSKKTHAVDEPDCNAVAVAPALTDQQLMRVAKHMGKEWKIVAISYLGFSNQNLEEMEAAEENATMLKFTMLERWRRRQPKGKAGVQELHNSLKDNDDVPNEVIAVLDEMLHNK", "length": 402, "header": "tr|A0AC58HEG2-1|A0AC58HEG2_DANRE Computationally mapped isoform of NACHT, LRR and PYD domains-containing protein 1b allele 3 isoform X4 OS=Danio rerio OX=7955 GN=si:dkeyp-97b10.3 PE=4 SV=1 CANONICAL=E7FGV0-1" }, "locus": {} }, { "isoform_ac": "E7FGV0-1", "url": "https://www.uniprot.org/uniprotkb/E7FGV0/entry#E7FGV0-1", "sequence": { "sequence": "MVAHMADYAETKHLTDGNGDVSPSDLKDHPAESSHSSSDSTSAEESSEEDETQEEEEDRESDSNTKAGAENHSDEPLASCCEKCRALKNPKYELVTPRKMSKERLQLQLDAEGVYECSDTGLVFEVSQRVKITYCVLSWSRFSTYLTGSWKFAGPIFDVDCDPAILKSIQFPHSLCLAADKDNEVNFSVLHVKNSRGLIEPSSDHSGSHVKWTVSSLSPVGPVVQTSRSAEHHGVVQVFRELGLESSSFSFRVYLARNICSDIKDIRKAVRRANNCKNNKKYILVDKPPTCMLEENRKYRLISEPVGHITPEDMLFTPDSVEVKGYIEVFFEDSPPFKLSLTDADSGQTVWTSTIREGDCTHHVEEMPKRPTKGTKRHSSTSDDELSYKRSKKTHAVDEPDCNAVAVAPALTDQQLMRVAKHMGKEWKIVAISYLGFSNQNLEEMEAAEENATMLKFTMLERWRRRQPKGKAGVQELHNSLKDNDDVPNEVIAVLDEMLHNK", "length": 502, "header": "tr|E7FGV0-1|E7FGV0_DANRE Isoform 1 of NACHT, LRR and PYD domains-containing protein 1a allele 5 isoform X1 OS=Danio rerio OX=7955 GN=si:dkeyp-97b10.3 PE=4 SV=1 CANONICAL=E7FGV0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100007012", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100007012", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E7FGV0", "url": "https://www.uniprot.org/uniprotkb/E7FGV0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E7FGV0", "url": "https://www.uniprot.org/uniprotkb/E7FGV0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 451, "end_pos": 453, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FGV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FGV0" }, { "id": "PS51830", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51830" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "FIIND", "eco_id": "ECO_0000259", "start_pos": 86, "end_pos": 369, "start_aa": "Ala", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 186, "end_pos": 188 }, { "start_pos": 451, "end_pos": 453 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F5H0-1", "uniprot_ac": "E7F5H0", "uniprot_id": "E7F5H0_DANRE", "mass": { "chemical_mass": 82361.0, "monoisotopic_mass": 82361.0 }, "refseq": { "ac": "XP_009304399", "name": "uncharacterized protein si:dkey-163f14.6 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304399" }, "gene_names": [ { "name": "si:dkey-163f14.6", "type": "recommended", "evidence": [ { "id": "E7F5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5H0" } ] }, { "name": "si:dkey-163f14.6", "type": "synonym", "evidence": [ { "id": "XP_009304399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304399" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkey-163f14.6 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5H0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkey-163f14.6 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_009304399", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304399" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009304399", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304399" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F5H0", "url": "https://www.uniprot.org/uniprotkb/E7F5H0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-163f14.6", "url": "https://www.uniprot.org/uniprotkb/E7F5H0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141215-18", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141215-18", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000091602", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000091602", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00033", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00033", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd00054", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00054", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100332398", "url": "https://www.ncbi.nlm.nih.gov/gene/100332398", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000152", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000152", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000436", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000436", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000742", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000742", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001881", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001881", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018097", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018097", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR026823", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026823", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035976", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035976", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR049883", "url": "https://www.ebi.ac.uk/interpro/entry/IPR049883", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052080", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052080", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052235", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052235", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100332398", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100332398", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SCVSGQW", "url": "https://omabrowser.org/oma/group/SCVSGQW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M1RKI4", "url": "https://www.orthodb.org/?gene=A0A8M1RKI4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F5H0", "url": "https://www.orthodb.org/?gene=E7F5H0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24050", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24050", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24050:SF27", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24050:SF27", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47333:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47333:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00084", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00084", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07645", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07645", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12662", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12662", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14670", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14670", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009304399", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304399", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M1RKI4", "url": "https://www.uniprot.org/uniprotkb/A0A8M1RKI4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M1RKI4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M1RKI4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F5H0", "url": "https://www.uniprot.org/uniprotkb/E7F5H0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F5H0-1", "url": "https://www.uniprot.org/uniprotkb/E7F5H0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-141215-18", "url": "https://zfin.org/ZDB-GENE-141215-18", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLGWRGTLLCAFLSPLWTLTPGSADKGCSGFGHLENGRMFFRYGGLYVTFTCNPGFRIHGYRTSSCVSGQWARDPPLCVASGCPGPGDLLHGSAVVSRDRSLASFSCDAGFYLSGSALLYCKGKNWNSTKPVCKVADIMSVLHLNQEFLHGPAYVPTSLKNHLHSHLNTMAITAHKDTFLKSALLEVPHVTLDLTDDKQTSRKPVEKKPSKSVLFAAEPIKNPENIKDLIRSSDLQKPVPVTSNVNTMSFASSFYNFILTTTSSSFNTPSVNSQQVKIMDQMFTETPYRRNEKGYQSTCVTDTTSVTTSAERLLEYLKNKPLTTLAPNINTLGTNDYLQSGILDNEHSATFKSPTASYPRFMLSENESANYLKPTAPSTCRGLCEQDVQKTSPSTNPIGHASSSMQITKIASDLPPVDVHRFIYNAEDQQVNDKSNQSDVKLTFESLEDLPSFPTRKRPVCPYPPFPSHGTFYFRSIKNPGPLQYKHYIQYACYPGYTLTSGDVYSYCEHDGQWSGQTPLCLELTPCSLHNGGCSQICRVNEHHRAQCVCKPGFLLLEDQRTCRDLDECVEELHLCQQACENTLGSYRCSCSPGFQLSADGTSCSDVDECQLVGRALCEFGCINTPGSFQCLCAEGHQLDSTNRHCIDINECEEEQLHMCEWKCVNLPGTYKCICPRGYRLHSNRHQCEDINECELKNGSCSHLCINHRGDYKCACPETHRISPYNPKNCLPVERHLKIT", "length": 740, "header": "tr|E7F5H0-1|E7F5H0_DANRE Isoform 1 of Uncharacterized protein si:dkey-163f14.6 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-163f14.6 PE=3 SV=1 CANONICAL=E7F5H0-1" }, "isoforms": [ { "isoform_ac": "A0A8M1RKI4-1", "url": "https://www.uniprot.org/uniprotkb/E7F5H0/entry#A0A8M1RKI4-1", "sequence": { "sequence": "MSSGCPGPGDLLHGSAVVSRDRSLASFSCDAGFYLSGSALLYCKGKNWNSTKPVCKVADIMSVLHLNQEFLHGPAYVPTSLKNHLHSHLNTMAITAHKDTFLKSALLEVPHVTLDLTDDKQTSRKPVEKKPSKSVLFAAEPIKNPENIKDLIRSSDLQKPVPVTSNVNTMSFASSFYNFILTTTSSSFNTPSVNSQQVKIMDQMFTETPYRRNEKGYQSTCVTDTTSVTTSAERLLEYLKNKPLTTLAPNINTLGTNDYLQSGILDNEHSATFKSPTASYPRFMLSENESANYLKPTAPSTCRGLCEQDVQKTSPSTNPIGHASSSMQITKIASDLPPVDVHRFIYNAEDQQVNDKSNQSDVKLTFESLEDLPSFPTRKRPVCPYPPFPSHGTFYFRSIKNPGPLQYKHYIQYACYPGYTLTSGDVYSYCEHDGQWSGQTPLCLELTPCSLHNGGCSQICRVNEHHRAQCVCKPGFLLLEDQRTCRDLDECVEELHLCQQACENTLGSYRCSCSPGFQLSADGTSCSDVDECQLVGRALCEFGCINTPGSFQCLCAEGHQLDSTNRHCIDINECEEEQLHMCEWKCVNLPGTYKCICPRGYRLHSNRHQCEDINECELKNGSCSHLCINHRGDYKCACPETHRISPYNPKNCLPVERHLKIT", "length": 662, "header": "tr|A0A8M1RKI4-1|E7F5H0_DANRE Computationally mapped isoform of Uncharacterized protein si:dkey-163f14.6 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-163f14.6 PE=3 SV=1 CANONICAL=E7F5H0-1" }, "locus": {} }, { "isoform_ac": "E7F5H0-1", "url": "https://www.uniprot.org/uniprotkb/E7F5H0/entry#E7F5H0-1", "sequence": { "sequence": "MLGWRGTLLCAFLSPLWTLTPGSADKGCSGFGHLENGRMFFRYGGLYVTFTCNPGFRIHGYRTSSCVSGQWARDPPLCVASGCPGPGDLLHGSAVVSRDRSLASFSCDAGFYLSGSALLYCKGKNWNSTKPVCKVADIMSVLHLNQEFLHGPAYVPTSLKNHLHSHLNTMAITAHKDTFLKSALLEVPHVTLDLTDDKQTSRKPVEKKPSKSVLFAAEPIKNPENIKDLIRSSDLQKPVPVTSNVNTMSFASSFYNFILTTTSSSFNTPSVNSQQVKIMDQMFTETPYRRNEKGYQSTCVTDTTSVTTSAERLLEYLKNKPLTTLAPNINTLGTNDYLQSGILDNEHSATFKSPTASYPRFMLSENESANYLKPTAPSTCRGLCEQDVQKTSPSTNPIGHASSSMQITKIASDLPPVDVHRFIYNAEDQQVNDKSNQSDVKLTFESLEDLPSFPTRKRPVCPYPPFPSHGTFYFRSIKNPGPLQYKHYIQYACYPGYTLTSGDVYSYCEHDGQWSGQTPLCLELTPCSLHNGGCSQICRVNEHHRAQCVCKPGFLLLEDQRTCRDLDECVEELHLCQQACENTLGSYRCSCSPGFQLSADGTSCSDVDECQLVGRALCEFGCINTPGSFQCLCAEGHQLDSTNRHCIDINECEEEQLHMCEWKCVNLPGTYKCICPRGYRLHSNRHQCEDINECELKNGSCSHLCINHRGDYKCACPETHRISPYNPKNCLPVERHLKIT", "length": 740, "header": "tr|E7F5H0-1|E7F5H0_DANRE Isoform 1 of Uncharacterized protein si:dkey-163f14.6 isoform X1 OS=Danio rerio OX=7955 GN=si:dkey-163f14.6 PE=3 SV=1 CANONICAL=E7F5H0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100332398", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100332398", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E7F5H0", "url": "https://www.uniprot.org/uniprotkb/E7F5H0" } ], "pmid": "" }, { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E7F5H0", "url": "https://www.uniprot.org/uniprotkb/E7F5H0" } ], "pmid": "" }, { "name": "extracellular matrix", "id": "GO:0031012", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031012", "evidence": [ { "database": "UniProtKB", "id": "E7F5H0", "url": "https://www.uniprot.org/uniprotkb/E7F5H0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "calcium ion binding", "id": "GO:0005509", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005509", "evidence": [ { "database": "UniProtKB", "id": "E7F5H0", "url": "https://www.uniprot.org/uniprotkb/E7F5H0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "elastic fiber assembly", "id": "GO:0048251", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048251", "evidence": [ { "database": "UniProtKB", "id": "E7F5H0", "url": "https://www.uniprot.org/uniprotkb/E7F5H0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 127, "end_pos": 129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 366, "end_pos": 368, "annotation": "n_glycosylation_sequon" }, { "start_pos": 436, "end_pos": 438, "annotation": "n_glycosylation_sequon" }, { "start_pos": 698, "end_pos": 700, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5H0" }, { "id": "PS50026", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50026" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EGF-like", "eco_id": "ECO_0000259", "start_pos": 565, "end_pos": 605, "start_aa": "Asp", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7F5H0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5H0" }, { "id": "PS50923", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Sushi", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 80, "start_aa": "Lys", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 127, "end_pos": 129 }, { "start_pos": 366, "end_pos": 368 }, { "start_pos": 436, "end_pos": 438 }, { "start_pos": 698, "end_pos": 700 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E9QJJ0-1", "uniprot_ac": "E9QJJ0", "uniprot_id": "E9QJJ0_DANRE", "mass": { "chemical_mass": 43268.0, "monoisotopic_mass": 43268.0 }, "refseq": { "ac": "XP_005156855", "name": "nucleolysin TIAR isoform X3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156855" }, "gene_names": [ { "name": "tial1", "type": "recommended", "evidence": [ { "id": "E9QJJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0" } ] }, { "name": "tial1", "type": "synonym", "evidence": [ { "id": "XP_005156855", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156855" } ] }, { "name": "zgc:66130", "type": "synonym", "evidence": [ { "id": "XP_005156855", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156855" }, { "id": "E9QJJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0" } ] } ], "protein_names": [ { "name": "Nucleolysin TIAR", "type": "recommended", "evidence": [ { "id": "E9QJJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0/entry#names_and_taxonomy" } ] }, { "name": "TIA-1-related protein", "type": "synonym", "evidence": [ { "id": "E9QJJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0/entry#names_and_taxonomy" } ] }, { "name": "nucleolysin TIAR isoform X3", "type": "synonym", "evidence": [ { "id": "XP_005156855", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156855" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005156855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156855" } ] }, { "annotation": "RNA-binding protein involved in alternative pre-RNA splicing and in cytoplasmic stress granules formation. Shows a preference for uridine-rich RNAs. Activates splicing of alternative exons with weak 5' splice sites followed by a U-rich stretch on its own pre-mRNA and on TIA1 mRNA. Promotes the inclusion of TIA1 exon 5 to give rise to the long isoform (isoform a) of TIA1. Acts downstream of the stress-induced phosphorylation of EIF2S1/EIF2A to promote the recruitment of untranslated mRNAs to cytoplasmic stress granules (SG). Possesses nucleolytic activity against cytotoxic lymphocyte target cells. May be involved in apoptosis.", "evidence": [ { "database": "UniProtKB", "id": "E9QJJ0", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0#function" }, { "database": "UniProtKB", "id": "ARBA00057653", "url": "https://www.uniprot.org/uniprotkb/ARBA00057653#function" }, { "database": "UniProtKB", "id": "A0A8M2B3J6", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B3J6#function" } ] } ], "disease": [ { "disease_id": "DOID:224", "recommended_name": { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "transient cerebral ischemia", "description": "A brain ischemia that is characterized by ischemia of brief duration and without resultant tissue death." }, "synonyms": [ { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "TIA", "description": "" }, { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "TIA - Transient ischaemic attack", "description": "" }, { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "Transient cerebral ischaemia", "description": "" }, { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "Transient ischemic attacks", "description": "" }, { "id": "DOID:224", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:224", "name": "transient ischemic attack", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "224", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:224" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QJJ0", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tial1", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040426-1547", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1547", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000009525", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000009525", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd12616", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12616", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12617", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12617", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd12620", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd12620", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "394107", "url": "https://www.ncbi.nlm.nih.gov/gene/394107", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003954", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003954", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034492", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034492", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034494", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034494", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034496", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034496", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "NIGHEVN", "url": "https://omabrowser.org/oma/group/NIGHEVN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2B2U9", "url": "https://www.orthodb.org/?gene=A0A8M2B2U9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2B338", "url": "https://www.orthodb.org/?gene=A0A8M2B338", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2B3J6", "url": "https://www.orthodb.org/?gene=A0A8M2B3J6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M3AZ31", "url": "https://www.orthodb.org/?gene=A0A8M3AZ31", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E9QJJ0", "url": "https://www.orthodb.org/?gene=E9QJJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10352", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10352", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005156855", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005156855", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B2U9", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B2U9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B2U9-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B2U9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B338", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B338", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B338-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B338-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B3J6", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B3J6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B3J6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B3J6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AZ31", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AZ31", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M3AZ31-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M3AZ31-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0P6", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0P6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0P6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0P6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0P8", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0P8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0P8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0P8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0P9", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0P9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0P9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0P9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0Q8", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0Q8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0Q8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0Q8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0R1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0R1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H0R1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H0R1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QJJ0", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QJJ0-1", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040426-1547", "url": "https://zfin.org/ZDB-GENE-040426-1547", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEDESHPKTLYVGNLSRDVTENLILQLFTQIGPCKSCKMITEQSDSSRKMNSSSIGFSVLQHTSNDPYCFVEFFEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMAKNVQPMEYGQWGQWNQMYGNPQQYGQYMTNGWQVPSYGMYGQTWNQQGFGVEQSQSPAWVGGFGTQPSQAQPGAVMNQANFGMAGYQTQ", "length": 389, "header": "tr|E9QJJ0-1|E9QJJ0_DANRE Isoform 1 of Nucleolysin TIAR OS=Danio rerio OX=7955 GN=tial1 PE=1 SV=1 CANONICAL=E9QJJ0-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B2U9-1", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0/entry#A0A8M2B2U9-1", "sequence": { "sequence": "MEDESHPKTLYVGNLSRDVTENLILQLFTQIGPCKSCKMITEHTSNDPYCFVEFFEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLVRLQYRNRVKDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMAKNVQPMEYGQWGQWNQMYGNPQQYGQYMTNGWQVPSYGMYGQTWNQQGFGVEQSQSPAWVGGFGTQPSQAQPGAVMNQANFGMAGYQTQ", "length": 380, "header": "tr|A0A8M2B2U9-1|E9QJJ0_DANRE Computationally mapped isoform of Nucleolysin TIAR OS=Danio rerio OX=7955 GN=tial1 PE=1 SV=1 CANONICAL=E9QJJ0-1" }, "locus": {} }, { "isoform_ac": "A0A8M2B338-1", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0/entry#A0A8M2B338-1", "sequence": { "sequence": "MEDESHPKTLYVGNLSRDVTENLILQLFTQIGPCKSCKMITEQSDSSRKMNSSSIGFSVLQHTSNDPYCFVEFFEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLVRLQYRNRVKDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMAKNVQPMEYGQWGQWNQMYGNPQQYGQYMTNGWQVPSYGMYGQTWNQQGFGVEQSQSPAWVGGFGTQPSQAQPGAVMNQANFGMAGYQTQ", "length": 399, "header": "tr|A0A8M2B338-1|E9QJJ0_DANRE Computationally mapped isoform of Nucleolysin TIAR OS=Danio rerio OX=7955 GN=tial1 PE=1 SV=1 CANONICAL=E9QJJ0-1" }, "locus": {} }, { "isoform_ac": "A0A8M2B3J6-1", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0/entry#A0A8M2B3J6-1", "sequence": { "sequence": "MEDESHPKTLYVGNLSRDVTENLILQLFTQIGPCKSCKMITESDSSRKMNSSSIGFSVLQHTSNDPYCFVEFFEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMAKNVQPMEYGQWGQWNQMYGNPQQYGQYMTNGWQVPSYGMYGQTWNQQGFGVEQSQSPAWVGGFGTQPSQAQPGAVMNQANFGMAGYQTQ", "length": 388, "header": "tr|A0A8M2B3J6-1|E9QJJ0_DANRE Computationally mapped isoform of Nucleolysin TIAR OS=Danio rerio OX=7955 GN=tial1 PE=1 SV=1 CANONICAL=E9QJJ0-1" }, "locus": {} }, { "isoform_ac": "A0A8M3AZ31-1", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0/entry#A0A8M3AZ31-1", "sequence": { "sequence": "MEDESHPKTLYVGNLSRDVTENLILQLFTQIGPCKSCKMITESDSSRKMNSSSIGFSVLQHTSNDPYCFVEFFEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLVRLQYRNRVKDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMAKNVQPMEYGQWGQWNQMYGNPQQYGQYMTNGWQVPSYGMYGQTWNQQGFGVEQSQSPAWVGGFGTQPSQAQPGAVMNQANFGMAGYQTQ", "length": 398, "header": "tr|A0A8M3AZ31-1|E9QJJ0_DANRE Computationally mapped isoform of Nucleolysin TIAR OS=Danio rerio OX=7955 GN=tial1 PE=1 SV=1 CANONICAL=E9QJJ0-1" }, "locus": {} }, { "isoform_ac": "A0AC58H0P6-1", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0/entry#A0AC58H0P6-1", "sequence": { "sequence": "MDARVVKDMTTGKSKGYGFVSFYNKLVRLQYRNRVKDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMAKNVQPMEYGQWGQWNQMYGNPQQYGQYMTNGWQVPSYGMYGQTWNQQGFGVEQSQSPAWVGGFGTQPSQAQPGAVMNQANFGMAGYQTQ", "length": 258, "header": "tr|A0AC58H0P6-1|A0AC58H0P6_DANRE Computationally mapped isoform of Nucleolysin TIAR isoform X8 OS=Danio rerio OX=7955 GN=tial1 PE=1 SV=1 CANONICAL=E9QJJ0-1" }, "locus": {} }, { "isoform_ac": "A0AC58H0P8-1", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0/entry#A0AC58H0P8-1", "sequence": { "sequence": "MTSELHLPPLGKSQMLIGLDRSLKANSKELCTLGTQMDARVVKDMTTGKSKGYGFVSFYNKLVRLQYRNRVKDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMAKNVQPMEYGQWGQWNQMYGNPQQYGQYMTNGWQVPSYGMYGQTWNQQGFGVEQSQSPAWVGGFGTQPSQAQPGAVMNQANFGMAGYQTQ", "length": 294, "header": "tr|A0AC58H0P8-1|A0AC58H0P8_DANRE Computationally mapped isoform of Nucleolysin TIAR isoform X6 OS=Danio rerio OX=7955 GN=tial1 PE=1 SV=1 CANONICAL=E9QJJ0-1" }, "locus": {} }, { "isoform_ac": "A0AC58H0P9-1", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0/entry#A0AC58H0P9-1", "sequence": { "sequence": "MTSELHLPPLGKSQMLIGLDRSLKANSKELCTLGTQMDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMAKNVQPMEYGQWGQWNQMYGNPQQYGQYMTNGWQVPSYGMYGQTWNQQGFGVEQSQSPAWVGGFGTQPSQAQPGAVMNQANFGMAGYQTQ", "length": 284, "header": "tr|A0AC58H0P9-1|A0AC58H0P9_DANRE Computationally mapped isoform of Nucleolysin TIAR isoform X7 OS=Danio rerio OX=7955 GN=tial1 PE=1 SV=1 CANONICAL=E9QJJ0-1" }, "locus": {} }, { "isoform_ac": "A0AC58H0Q8-1", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0/entry#A0AC58H0Q8-1", "sequence": { "sequence": "MGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMAKNVQPMEYGQWGQWNQMYGNPQQYGQYMTNGWQVPSYGMYGQTWNQQGFGVEQSQSPAWVGGFGTQPSQAQPGAVMNQANFGMAGYQTQ", "length": 214, "header": "tr|A0AC58H0Q8-1|A0AC58H0Q8_DANRE Computationally mapped isoform of Nucleolysin TIAR isoform X10 OS=Danio rerio OX=7955 GN=tial1 PE=1 SV=1 CANONICAL=E9QJJ0-1" }, "locus": {} }, { "isoform_ac": "A0AC58H0R1-1", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0/entry#A0AC58H0R1-1", "sequence": { "sequence": "MDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMAKNVQPMEYGQWGQWNQMYGNPQQYGQYMTNGWQVPSYGMYGQTWNQQGFGVEQSQSPAWVGGFGTQPSQAQPGAVMNQANFGMAGYQTQ", "length": 248, "header": "tr|A0AC58H0R1-1|A0AC58H0R1_DANRE Computationally mapped isoform of Nucleolysin TIAR isoform X9 OS=Danio rerio OX=7955 GN=tial1 PE=1 SV=1 CANONICAL=E9QJJ0-1" }, "locus": {} }, { "isoform_ac": "E9QJJ0-1", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0/entry#E9QJJ0-1", "sequence": { "sequence": "MEDESHPKTLYVGNLSRDVTENLILQLFTQIGPCKSCKMITEQSDSSRKMNSSSIGFSVLQHTSNDPYCFVEFFEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTDDIRAAFAPFGKISDARVVKDMTTGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSVQDNSAKQLRFDEVVNQSSPQNCTVYCGGIQSGLTEHLMRQTFSPFGQIMEIRVFPEKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMAKNVQPMEYGQWGQWNQMYGNPQQYGQYMTNGWQVPSYGMYGQTWNQQGFGVEQSQSPAWVGGFGTQPSQAQPGAVMNQANFGMAGYQTQ", "length": 389, "header": "tr|E9QJJ0-1|E9QJJ0_DANRE Isoform 1 of Nucleolysin TIAR OS=Danio rerio OX=7955 GN=tial1 PE=1 SV=1 CANONICAL=E9QJJ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AQH6-1", "protein_name": "Cytotoxic granule associated RNA binding protein TIA1", "gene_name": "Tia1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDQTAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPGNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFIRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPPAYGQWGQWYGNAQQIGQYVPNGWQVPAYGMYGQPWSQQGFNQTQSSAPWMGPNYSVPPPQGQNGGMLPNQPAGYRVAGYETQ", "length": 387 }, "evidence": [ { "id": "FB:FBgn0005649", "url": "https://alliancegenome.org/gene/FB:FBgn0005649#orthology", "database": "AGR" }, { "id": "FB:FBgn0085383", "url": "https://alliancegenome.org/gene/FB:FBgn0085383#orthology", "database": "AGR" }, { "id": "FB:FBgn0085391", "url": "https://alliancegenome.org/gene/FB:FBgn0085391#orthology", "database": "AGR" }, { "id": "SGD:S000004961", "url": "https://alliancegenome.org/gene/SGD:S000004961#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A8JPX0-1", "protein_name": "RRM domain-containing protein", "gene_name": "CG12852", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLTMSTLMMPAPTIAMGAPQITMGPHKPPETKLLAIHPAAAAAAAAQQQQQSVTAAHLQHNGQQQHSQQQQQQQMSQQQQQQQQQLVGNNSKPEQFHIFVGDLSAEIETQQLKDAFTPFGEISDCRVVRDPQTLKSKGYGFVSFVKKSEAETAITAMNGQWLGSRSIRTNWATRKPPATKADMNAKPLTFDEVYNQSSPTNCTVYCGGINGALSGFLNEEILQKTFSPYGTIQEIRVFKDKGYAFVRFSTKEAATHAIVAVNNTEINQQPVKCAWGKESGDPNHMSAIAGGALAQGFPFGSAAAAAAAAAYGQQVAGYWYPPAPTYPAAAPASALQPGQFLQGMQGFTYGQFAGYQQAGYMGMGVQLPGTWQSVPPQPQLASAAAATAPQITQSVGSALPQAAGVVAYPMQQFQVSPQLAEDEWLAPSLLVXLPXGMAMYPTQQHQQQQQQQQQQQMLQQQHEQQTSGEYVKEPPYQTQQLQQLQHHQLQQQHSHNQHQQQQHYIHQLYYPSHWVQQQQQQQQQVANNEQQPQQQQQQPPVAQVYGMSEV", "length": 550 }, "evidence": [ { "id": "MGI:107913", "url": "https://alliancegenome.org/gene/MGI:107913#orthology", "database": "AGR" }, { "id": "HGNC:11804", "url": "https://alliancegenome.org/gene/HGNC:11804#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1547", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1547#orthology", "database": "AGR" }, { "id": "FB:FBgn0085383", "url": "https://alliancegenome.org/gene/FB:FBgn0085383#orthology", "database": "AGR" }, { "id": "RGD:1595845", "url": "https://alliancegenome.org/gene/RGD:1595845#orthology", "database": "AGR" }, { "id": "SGD:S000004961", "url": "https://alliancegenome.org/gene/SGD:S000004961#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "E1JIZ9-1", "protein_name": "Trivet, isoform I", "gene_name": "trv", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPASGNGCCSTRTAGCCQDCSGYQQGYEHLPVPRLQHQQPPPPLYQNQQQKQDHQQGSCTSTLQQTTTTTSNCSYGNCLMPAPATTSTYVSNIGTEPPLLSMQYCRSHCNMQHCNSTGGSNKAPAIYNNIPAQSMIFVPVMLPMQQQHPQQQQHDLHMQHPLTPSEDCKPLLHAKSVPPPPQPPPMLTHFQAMMQPPPLPPSPMMPPQSFGCPLPSRTPATPPLPGTYRVQSLKSAAAAAVSAYQRNGKLPRNLPALRAMEMALRTNSFATPPAPHSLPLPPPHAARTEGGGQDMEDSDEEMEYMPPLHKQFHIFVGDLSSEIETQQLREAFTPFGEISDCRVVRDPQTLKSKGYGFVSFIKKSEAESAITAMNGQWLGSRSIRTNWATRKPPASKENIKPLTFDEVYNQSSPSNCTVYVGGVNSALTALSEEVLQKTFAPYGAIQEIRVFKDKGYAFVRFSTKEAATHAIVGVHNTEINAQPVKCSWGKESGDPNNAQTIATQALNSAAAAAAGFPYGVGAAAAAAAYGQQLAATGCWYSPTPTYPASSATAAAVTPAAASAAAVQNQFLQGIQGYHFGQYGGYQQGYMGMGVQIPATWQGVTQAQISPAQQLATGVAGTAIPQAAGVVAYPIQQFQVSPQVYPLLLQAQ", "length": 651 }, "evidence": [ { "id": "MGI:107913", "url": "https://alliancegenome.org/gene/MGI:107913#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1547", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1547#orthology", "database": "AGR" }, { "id": "FB:FBgn0085391", "url": "https://alliancegenome.org/gene/FB:FBgn0085391#orthology", "database": "AGR" }, { "id": "RGD:1595845", "url": "https://alliancegenome.org/gene/RGD:1595845#orthology", "database": "AGR" }, { "id": "SGD:S000004961", "url": "https://alliancegenome.org/gene/SGD:S000004961#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P31483-1", "protein_name": "Cytotoxic granule associated RNA binding protein TIA1", "gene_name": "TIA1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVNQSSPSNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFNSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPQPYGQWGQWYGNAQQIGQYMPNGWQVPAYGMYGQAWNQQGFNQTQSSAPWMGPNYGVQPPQGQNGSMLPNQPSGYRVAGYETQ", "length": 386 }, "evidence": [ { "id": "FB:FBgn0005649", "url": "https://alliancegenome.org/gene/FB:FBgn0005649#orthology", "database": "AGR" }, { "id": "FB:FBgn0085383", "url": "https://alliancegenome.org/gene/FB:FBgn0085383#orthology", "database": "AGR" }, { "id": "FB:FBgn0085391", "url": "https://alliancegenome.org/gene/FB:FBgn0085391#orthology", "database": "AGR" }, { "id": "SGD:S000004961", "url": "https://alliancegenome.org/gene/SGD:S000004961#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P32588-1", "protein_name": "Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1", "gene_name": "PUB1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MSENNEEQHQQQQQQQPVAVETPSAVEAPASADPSSEQSVAVEGNSEQAEDNQGENDPSVVPANAITGGRETSDRVLYVGNLDKAITEDILKQYFQVGGPIANIKIMIDKNNKNVNYAFVEYHQSHDANIALQTLNGKQIENNIVKINWAFQSQQSSSDDTFNLFVGDLNVNVDDETLRNAFKDFPSYLSGHVMWDMQTGSSRGYGFVSFTSQDDAQNAMDSMQGQDLNGRPLRINWAAKRDNNNNNNYQQRRNYGNNNRGGFRQYNSNNNNNMNMGMNMNMNMNMNNSRGMPPSSMGMPIGAMPLPSQGQPQQSQTIGLPPQVNPQAVDHIIRSAPPRVTTAYIGNIPHFATEADLIPLFQNFGFILDFKHYPEKGCCFIKYDTHEQAAVCIVALANFPFQGRNLRTGWGKERSNFMPQQQQQGGQPLIMNDQQQPVMSEQQQQQQQQQQQQ", "length": 453 }, "evidence": [ { "id": "MGI:107913", "url": "https://alliancegenome.org/gene/MGI:107913#orthology", "database": "AGR" }, { "id": "HGNC:11804", "url": "https://alliancegenome.org/gene/HGNC:11804#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1547", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1547#orthology", "database": "AGR" }, { "id": "FB:FBgn0005649", "url": "https://alliancegenome.org/gene/FB:FBgn0005649#orthology", "database": "AGR" }, { "id": "FB:FBgn0085383", "url": "https://alliancegenome.org/gene/FB:FBgn0085383#orthology", "database": "AGR" }, { "id": "FB:FBgn0085391", "url": "https://alliancegenome.org/gene/FB:FBgn0085391#orthology", "database": "AGR" }, { "id": "RGD:1595845", "url": "https://alliancegenome.org/gene/RGD:1595845#orthology", "database": "AGR" }, { "id": "SGD:S000004961", "url": "https://alliancegenome.org/gene/SGD:S000004961#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "P52912-1", "protein_name": "Cytotoxic granule associated RNA binding protein TIA1", "gene_name": "Tia1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDEMPKTLYVGNLSRDVTEALILQLFSQIGPCKNCKMIMDTAGNDPYCFVEFHEHRHAAAALAAMNGRKIMGKEVKVNWATTPSSQKKDTSSSTVVSTQRSQDHFHVFVGDLSPEITTEDIKAAFAPFGRISDARVVKDMATGKSKGYGFVSFFNKWDAENAIQQMGGQWLGGRQIRTNWATRKPPAPKSTYESNTKQLSYDEVVSQSSPNNCTVYCGGVTSGLTEQLMRQTFSPFGQIMEIRVFPDKGYSFVRFSSHESAAHAIVSVNGTTIEGHVVKCYWGKETLDMINPVQQQNQIGYPPTYGQWGQWYGNAQQIGQYVPNGWQVPAYGVYGQPWSQQGFNQTQSSAPWMGPNYSVPPPQGQNGSMLPSQPAGYRVAGYETQ", "length": 386 }, "evidence": [ { "id": "FB:FBgn0005649", "url": "https://alliancegenome.org/gene/FB:FBgn0005649#orthology", "database": "AGR" }, { "id": "FB:FBgn0085383", "url": "https://alliancegenome.org/gene/FB:FBgn0085383#orthology", "database": "AGR" }, { "id": "FB:FBgn0085391", "url": "https://alliancegenome.org/gene/FB:FBgn0085391#orthology", "database": "AGR" }, { "id": "SGD:S000004961", "url": "https://alliancegenome.org/gene/SGD:S000004961#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P70318-1", "protein_name": "Nucleolysin TIAR", "gene_name": "Tial1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEQPDSRRVNSSVGFSVLQHTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQETNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIPPPNQAGYGMASFPTQ", "length": 392 }, "evidence": [ { "id": "MGI:107913", "url": "https://alliancegenome.org/gene/MGI:107913#orthology", "database": "AGR" }, { "id": "HGNC:11804", "url": "https://alliancegenome.org/gene/HGNC:11804#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1547", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1547#orthology", "database": "AGR" }, { "id": "FB:FBgn0005649", "url": "https://alliancegenome.org/gene/FB:FBgn0005649#orthology", "database": "AGR" }, { "id": "FB:FBgn0085383", "url": "https://alliancegenome.org/gene/FB:FBgn0085383#orthology", "database": "AGR" }, { "id": "FB:FBgn0085391", "url": "https://alliancegenome.org/gene/FB:FBgn0085391#orthology", "database": "AGR" }, { "id": "RGD:1595845", "url": "https://alliancegenome.org/gene/RGD:1595845#orthology", "database": "AGR" }, { "id": "SGD:S000004961", "url": "https://alliancegenome.org/gene/SGD:S000004961#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q01085-1", "protein_name": "Nucleolysin TIAR", "gene_name": "TIAL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMEDDGQPRTLYVGNLSRDVTEVLILQLFSQIGPCKSCKMITEHTSNDPYCFVEFYEHRDAAAALAAMNGRKILGKEVKVNWATTPSSQKKDTSNHFHVFVGDLSPEITTEDIKSAFAPFGKISDARVVKDMATGKSKGYGFVSFYNKLDAENAIVHMGGQWLGGRQIRTNWATRKPPAPKSTQENNTKQLRFEDVVNQSSPKNCTVYCGGIASGLTDQLMRQTFSPFGQIMEIRVFPEKGYSFVRFSTHESAAHAIVSVNGTTIEGHVVKCYWGKESPDMTKNFQQVDYSQWGQWSQVYGNPQQYGQYMANGWQVPPYGVYGQPWNQQGFGVDQSPSAAWMGGFGAQPPQGQAPPPVIPPPNQAGYGMASYQTQ", "length": 375 }, "evidence": [ { "id": "MGI:107913", "url": "https://alliancegenome.org/gene/MGI:107913#orthology", "database": "AGR" }, { "id": "HGNC:11804", "url": "https://alliancegenome.org/gene/HGNC:11804#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1547", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1547#orthology", "database": "AGR" }, { "id": "FB:FBgn0005649", "url": "https://alliancegenome.org/gene/FB:FBgn0005649#orthology", "database": "AGR" }, { "id": "FB:FBgn0085383", "url": "https://alliancegenome.org/gene/FB:FBgn0085383#orthology", "database": "AGR" }, { "id": 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"https://alliancegenome.org/gene/HGNC:11804#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1547", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1547#orthology", "database": "AGR" }, { "id": "FB:FBgn0005649", "url": "https://alliancegenome.org/gene/FB:FBgn0005649#orthology", "database": "AGR" }, { "id": "FB:FBgn0085383", "url": "https://alliancegenome.org/gene/FB:FBgn0085383#orthology", "database": "AGR" }, { "id": "FB:FBgn0085391", "url": "https://alliancegenome.org/gene/FB:FBgn0085391#orthology", "database": "AGR" }, { "id": "RGD:1595845", "url": "https://alliancegenome.org/gene/RGD:1595845#orthology", "database": "AGR" }, { "id": "SGD:S000004961", "url": "https://alliancegenome.org/gene/SGD:S000004961#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8IMX4-1", "protein_name": "Rox8, isoform E", "gene_name": "Rox8", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDESQPKTLYVGNLDSSVSEDLLIALFSTMGPVKSCKIIREPGNDPYAFIEYSNYQAATTALTAMNKRLFLEKEIKVNWATSPGNQPKTDISSHHHIFVGDLSPEIETETLREAFAPFGEISNCRIVRDPHTMKSKGYAFVSFVKKAEAENAIQAMNGQWIGSRSIRTNWSTRKLPPPREPSKGGGQGGGMGGGPGNGSGVKGSQRHTFEEVYNQSSPTNTTVYCGGFPPNVISDDLMHKHFVQFGPIQDVRVFKDKGFSFIKFVTKEAAAHAIEHTHNSEVHGNLVKCFWGKENGGDNSANNLNAAAAAAAASANVAAVAAANAAVAAGAGMPGQMMTQQQIAAATGAAIPGQMMTPQQIAAQYPYAYQQMGYWYPPATYPTTQMQTQYMQQGYYPYAYPTSAQQAGGVPCIQFSAAGYRMVPPNVAWGVPGTVVPGVTAAAASAAAAANGSLAPQMMYSAAMPQYQTQ", "length": 470 }, "evidence": [ { "id": "MGI:107913", "url": "https://alliancegenome.org/gene/MGI:107913#orthology", "database": "AGR" }, { "id": "HGNC:11804", "url": "https://alliancegenome.org/gene/HGNC:11804#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-1547", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-1547#orthology", "database": "AGR" }, { "id": "FB:FBgn0005649", "url": "https://alliancegenome.org/gene/FB:FBgn0005649#orthology", "database": "AGR" }, { "id": "RGD:1595845", "url": 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"https://www.uniprot.org/uniprotkb/E9QJJ0" } ], "pmid": "" }, { "name": "mRNA 3'-UTR binding", "id": "GO:0003730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003730", "evidence": [ { "database": "UniProtKB", "id": "E9QJJ0", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "regulation of alternative mRNA splicing, via spliceosome", "id": "GO:0000381", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000381", "evidence": [ { "database": "UniProtKB", "id": "E9QJJ0", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0" } ], "pmid": "" }, { "name": "regulation of cell population proliferation", "id": "GO:0042127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042127", "evidence": [ { "database": "UniProtKB", "id": "E9QJJ0", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E9QJJ0", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E9QJJ0", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0" } ], "pmid": "" }, { "name": "cytoplasmic stress granule", "id": "GO:0010494", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0010494", "evidence": [ { "database": "UniProtKB", "id": "E9QJJ0", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0" } ], "pmid": "" }, { "name": "cytolytic granule", "id": "GO:0044194", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0044194", "evidence": [ { "database": "UniProtKB", "id": "E9QJJ0", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 14, "end_pos": 16, "annotation": "n_glycosylation_sequon" }, { "start_pos": 216, "end_pos": 218, "annotation": "n_glycosylation_sequon" }, { "start_pos": 222, "end_pos": 224, "annotation": "n_glycosylation_sequon" }, { "start_pos": 279, "end_pos": 281, "annotation": "n_glycosylation_sequon" }, { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E9QJJ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJJ0" }, { "id": "PS50102", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50102" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RRM", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 103, "start_aa": "Lys", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 14, "end_pos": 16 }, { "start_pos": 216, "end_pos": 218 }, { "start_pos": 222, "end_pos": 224 }, { "start_pos": 279, "end_pos": 281 }, { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": 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} ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B8A4M7-1", "uniprot_ac": "B8A4M7", "uniprot_id": "B8A4M7_DANRE", "mass": { "chemical_mass": 27617.0, "monoisotopic_mass": 27617.0 }, "refseq": { "ac": "NP_001139093", "name": "IQ domain-containing protein C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139093" }, "gene_names": [ { "name": "iqcc", "type": "recommended", "evidence": [ { "id": "B8A4M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4M7" } ] }, { "name": "iqcc", "type": "synonym", "evidence": [ { "id": "NP_001139093", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139093" } ] }, { "name": "si:dkey-71p21.11", "type": "synonym", "evidence": [ { "id": "NP_001139093", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139093" }, { "id": "B8A4M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4M7" } ] } ], "protein_names": [ { "name": "IQ domain-containing protein C", "type": "synonym", "evidence": [ { "id": "NP_001139093", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139093" }, { "id": "B8A4M7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4M7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH444115.1, SRR32588728.26862716.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000013.1. On Mar 5, 2009 this sequence version replaced XP_001339683.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001139093", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139093" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A4M7", "url": "https://www.uniprot.org/uniprotkb/B8A4M7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "iqcc", "url": "https://www.uniprot.org/uniprotkb/B8A4M7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-325", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-325", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092483", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092483", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "799312", "url": "https://www.ncbi.nlm.nih.gov/gene/799312", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR042506", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042506", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:799312", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799312", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "AMEMLWL", "url": "https://omabrowser.org/oma/group/AMEMLWL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2B318", "url": "https://www.orthodb.org/?gene=A0A8M2B318", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "B8A4M7", "url": "https://www.orthodb.org/?gene=B8A4M7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16049", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16049", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16049:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16049:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001139093", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139093", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B318", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B318", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B318-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B318-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2B5", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2B5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2B5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2B5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A4M7", "url": "https://www.uniprot.org/uniprotkb/B8A4M7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A4M7-1", "url": "https://www.uniprot.org/uniprotkb/B8A4M7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-325", "url": "https://zfin.org/ZDB-GENE-090313-325", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNEQKWIQTLTQFQAHCRGCVMRRGLSLVQAQFEDIVQEIDGGLDHLQWRGNIIPRPHFTDTESLLLRYERSRIQCHDLLDRSEKEQNEECEKCLPQSDIHVPEKDEAPEAARSETSTHVDDVEDKRGDIMVIQNLMDDCSTLCSDLNSDVRQSSLFQTAGPGLHTLLKDTTHTPESLKQQRSTLAMELLWIQQAISSRKKVRKVDMLLSIFANVYLILDVPFHFLHQNKFTKWNVYI", "length": 238, "header": "tr|B8A4M7-1|B8A4M7_DANRE Isoform 1 of IQ domain-containing protein C OS=Danio rerio OX=7955 GN=iqcc PE=4 SV=1 CANONICAL=B8A4M7-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B318-1", "url": "https://www.uniprot.org/uniprotkb/B8A4M7/entry#A0A8M2B318-1", "sequence": { "sequence": "MNEQKWIQTLTQFQAHCRGCVMRRGLSLVQAQFEDIVQEIDGGLDHLQWRGNIIPRPHFTDTESLLLRYERSRIQCHDLLDRSEKEQNEECEKCLPQSDIHVPEKDEAPEAARSETSTHVDDVEDKRGDIMVIQNLMDDCSTLCSDLNSDVRQSSLFQTGPGLHTLLKDTTHTPESLKQQRSTLAMELLWIQQAISSRKKYLTLKQRMDVSH", "length": 212, "header": "tr|A0A8M2B318-1|B8A4M7_DANRE Computationally mapped isoform of IQ domain-containing protein C OS=Danio rerio OX=7955 GN=iqcc PE=4 SV=1 CANONICAL=B8A4M7-1" }, "locus": {} }, { "isoform_ac": "A0AC58H2B5-1", "url": "https://www.uniprot.org/uniprotkb/B8A4M7/entry#A0AC58H2B5-1", "sequence": { "sequence": "MNEQKWIQTLTQFQAHCRGCVMRRGLSLVQAQFEDIVQEIDGGLDHLQWRGNIIPRPHFTDTESLLLRYERSRIQCHDLLDRSEKEQNEECEKCLPQSDIHVPEKDEAPEAARSETSTHVDDVEDKRGDIMVIQNLMDDCSTLCSDLNSDVRQSSLFQTAGPGLHTLLKDTTHTPESLKQQRSTLAMELLWIQQAISSRKKYLTLKQRMDVSH", "length": 213, "header": "tr|A0AC58H2B5-1|A0AC58H2B5_DANRE Computationally mapped isoform of IQ domain-containing protein C isoform X1 OS=Danio rerio OX=7955 GN=iqcc PE=4 SV=1 CANONICAL=B8A4M7-1" }, "locus": {} }, { "isoform_ac": "B8A4M7-1", "url": "https://www.uniprot.org/uniprotkb/B8A4M7/entry#B8A4M7-1", "sequence": { "sequence": "MNEQKWIQTLTQFQAHCRGCVMRRGLSLVQAQFEDIVQEIDGGLDHLQWRGNIIPRPHFTDTESLLLRYERSRIQCHDLLDRSEKEQNEECEKCLPQSDIHVPEKDEAPEAARSETSTHVDDVEDKRGDIMVIQNLMDDCSTLCSDLNSDVRQSSLFQTAGPGLHTLLKDTTHTPESLKQQRSTLAMELLWIQQAISSRKKVRKVDMLLSIFANVYLILDVPFHFLHQNKFTKWNVYI", "length": 238, "header": "tr|B8A4M7-1|B8A4M7_DANRE Isoform 1 of IQ domain-containing protein C OS=Danio rerio OX=7955 GN=iqcc PE=4 SV=1 CANONICAL=B8A4M7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8A4M7", "url": "https://www.uniprot.org/uniprotkb/B8A4M7" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8A4M7", "url": "https://www.uniprot.org/uniprotkb/B8A4M7" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:799312", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:799312", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Z1F6-1", "protein_name": "IQ motif containing C", "gene_name": "IQCC", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAAAPGPREEAEERRRLLRAVTRLQAGVRGFLLRRRLRSVRAEYEEVVREIEGDLSELQWRGLCLPRPVFVPKPMKEKCSAMQEAVSNDKDSTEKTQQELDVSKPERDWGSSNSVKPTAQLQSEKELNSMGGCNAARPSNLGAAAGKSTERRCSAPAQSKEWQNTSSISSVWDSTDLEPGSLKACLEIPLVDVKELPRTRPGLQSFRNHLIMELLWLQQAIDSRKNYLKLKQRLESPDS", "length": 239 }, "evidence": [ { "id": "B8A4M7", "url": "https://omabrowser.org/oma/group/B8A4M7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A2ADZ8-1", "protein_name": "IQ domain-containing protein C", "gene_name": "Iqcc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDPDLFLRKVSTLQAGFRGFLVRRQFQSLRAEYEAIVQEIEGDLSTLQWTGGWIPKPVFLPEAKSHQSWKAEKISNPEQKLWSHSPHKDSEKELIWEEMVQKKTEKSPANPGSLCRDDSAWPQAEQGRKASQGNSQDTSVSKMENADLGLSQSQQELQEQRNHLAMELLWLQQAINSRKEYLILKQTLRSPEASQTRDKHRGQAYEKTSLHSSCVLDNQSYRDRIIGESHHAEDSSHKGRLKPQKHPDSVTSAGKTTAGSKGRELCYRNSASQLPAALESQAGGDRVTKGPDHGGQPFKETSLQQLKVLEDQIPGDLKFRSPCSRKAETQLPTLSENQNIEDRYSRKPSRSAGPCDLNILEGHMIWDETLAGQEQGSLDLIRTKPPKSQPPSAGSSGHGNTSELSPEGWKNRGILQWR", "length": 418 }, "evidence": [ { "id": "MGI:2446212", "url": "https://alliancegenome.org/gene/MGI:2446212#orthology", "database": "AGR" }, { "id": "HGNC:25545", "url": "https://alliancegenome.org/gene/HGNC:25545#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-325", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-325#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0RCW8-1", "protein_name": "IQ motif containing C", "gene_name": "Iqcc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPDLFLRKVSTLQAGFRGFLVRRQFQSLRAEYEAIVEEIEGDVRTLRWTGGWIPKPIFLPEAKSHRSWKIEKIPNPEQKLSSHSPHKDSEKELLWEEMVLRKTDKNPAEPGSLCRGDSAWPQAEPGRKASQGNSRDPSISKVQSAVTDLGLSQTQQELQEQRNHLAMELLWLQQAINSRKEYLILKQTLRSPEASQIRDKPTKMCLKHRGQAYEETWLQSSCVLDNQSYRDGVIGEPHHAEDSCHRGTLQPQKPPDSMTSTSKATAGAKGGELYRNSGSQLPTALESQAGGVRVTKGPDRGGQPFNETSRQQLKLLEDQTLRDLKLRSSYSGKVETQLPTLSENLNIEDRYSRKPSYKEADWPERRAL", "length": 369 }, "evidence": [ { "id": "MGI:2446212", "url": "https://alliancegenome.org/gene/MGI:2446212#orthology", "database": "AGR" }, { "id": "HGNC:25545", "url": "https://alliancegenome.org/gene/HGNC:25545#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q4KMZ1-1", "protein_name": "IQ domain-containing protein C", "gene_name": "IQCC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEPELLVRKVSALQACVRGFLVRRQFQSLRAEYEAIVREVEGDLGTLQWTEGRIPRPRFLPEKAKSHQTWKAGDRVANPEQGLWNHFPCEESEGEATWEEMVLKKSGESSANQGSLCRDHSSWLQMKQNRKPSQEKTRDTTRMENPEATDQRLPHSQPQLQELQYHRSHLAMELLWLQQAINSRKEYLLLKQTLRSPEAGPIREEPRVFLEHGEQACERDQSQPSAPLEDQSYRDRTTGELEQEDDSCHRVKSPHRSPGSLATTQKNIAGAKCREPCYSKSGPPSSIPSNSQALGDRLTKGPDDGRQTFGGTCLLQMKILEDQTPRGLKPRNHCPRKSRTQLSALYEDSNIKEMSPRKLDHKEPDCRTVRTQELGLSEDHIIWDGTLGGPEHSVLDLWRTKPPKGQAPTDRSSRDGTSNEPSHEGQKKQRTIPWRSKSPEILSSTKAGCTGEEQWRGRPWKTEPPG", "length": 466 }, "evidence": [ { "id": "MGI:2446212", "url": "https://alliancegenome.org/gene/MGI:2446212#orthology", "database": "AGR" }, { "id": "HGNC:25545", "url": "https://alliancegenome.org/gene/HGNC:25545#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-325", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-325#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E9QJH9-1", "uniprot_ac": "E9QJH9", "uniprot_id": "E9QJH9_DANRE", "mass": { "chemical_mass": 18289.0, "monoisotopic_mass": 18289.0 }, "refseq": { "ac": "NP_001314699", "name": "CB1 cannabinoid receptor-interacting protein 1b", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314699" }, "gene_names": [ { "name": "cnrip1b", "type": "recommended", "evidence": [ { "id": "E9QJH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJH9" } ] }, { "name": "cnrip1b", "type": "synonym", "evidence": [ { "id": "NP_001314699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314699" } ] }, { "name": "cnrip1", "type": "synonym", "evidence": [ { "id": "NP_001314699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314699" }, { "id": "E9QJH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJH9" } ] } ], "protein_names": [ { "name": "CB1 cannabinoid receptor-interacting protein 1b", "type": "synonym", "evidence": [ { "id": "NP_001314699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314699" }, { "id": "E9QJH9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QJH9/entry#names_and_taxonomy" } ] }, { "name": "cannabinoid receptor interacting protein 1", "type": "synonym", "evidence": [ { "id": "NP_001314699", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314699" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CB363647.1, EB953146.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1 and EB953146.1. On May 25, 2016 this sequence version replaced XP_684894.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001314699", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314699" } ] }, { "annotation": "Fish lacking both Cnrip1a and Cnrip1b both maternally and zygotically are viable and fertile and no phenotype has so far been detected despite strong evolutionary conservation over at least 400 Myr. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001314699", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314699" }, { "database": "PubMed", "id": "28687732", "url": "https://glygen.org/publication/PubMed/28687732" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QJH9", "url": "https://www.uniprot.org/uniprotkb/E9QJH9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cnrip1b", "url": "https://www.uniprot.org/uniprotkb/E9QJH9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080722-33", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080722-33", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000037337", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000037337", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "556881", "url": "https://www.ncbi.nlm.nih.gov/gene/556881", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029204", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029204", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556881", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556881", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YCKMETS", "url": "https://omabrowser.org/oma/group/YCKMETS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2B3D2", "url": "https://www.orthodb.org/?gene=A0A8M2B3D2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E9QJH9", "url": "https://www.orthodb.org/?gene=E9QJH9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31952", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31952", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31952:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31952:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15043", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15043", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PR:E9QJH9", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:E9QJH9", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001314699", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314699", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B3D2", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B3D2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B3D2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B3D2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QJH9", "url": "https://www.uniprot.org/uniprotkb/E9QJH9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QJH9-1", "url": "https://www.uniprot.org/uniprotkb/E9QJH9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080722-33", "url": "https://zfin.org/ZDB-GENE-080722-33", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MADIPQLIKIGVSLKTTPNNGAVYFKSDGTRFGQTRTIKLLTGTKYKMDVVVKPGAVEATSMTVGGVTFPLEQQSKDPQSVVYSGMYNTEGVTHTKSGERQPVQVSIQFTQAGVFETVWQVKFYNYNKRDHCQWGNSFNSIEYECKPNDTHTLMWINKEMFL", "length": 162, "header": "tr|E9QJH9-1|E9QJH9_DANRE Isoform 1 of CB1 cannabinoid receptor-interacting protein 1b OS=Danio rerio OX=7955 GN=cnrip1b PE=4 SV=1 CANONICAL=E9QJH9-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B3D2-1", "url": "https://www.uniprot.org/uniprotkb/E9QJH9/entry#A0A8M2B3D2-1", "sequence": { "sequence": "MADIPQLIKIGVSLKTTPNNGAVYFKSDGTRFGQTRTIKLLTGTKYKMDVVVKPGAVEATSMTVGGVTFPLEQQSKDPQSVVYSGMYNTEGVTHTKSGERQPVQFTQAGVFETVWQVKFYNYNKRDHCQWGNSFNSIEYECKPNDTHTLMWINKEMFL", "length": 158, "header": "tr|A0A8M2B3D2-1|E9QJH9_DANRE Computationally mapped isoform of CB1 cannabinoid receptor-interacting protein 1b OS=Danio rerio OX=7955 GN=cnrip1b PE=4 SV=1 CANONICAL=E9QJH9-1" }, "locus": {} }, { "isoform_ac": "E9QJH9-1", "url": "https://www.uniprot.org/uniprotkb/E9QJH9/entry#E9QJH9-1", "sequence": { "sequence": "MADIPQLIKIGVSLKTTPNNGAVYFKSDGTRFGQTRTIKLLTGTKYKMDVVVKPGAVEATSMTVGGVTFPLEQQSKDPQSVVYSGMYNTEGVTHTKSGERQPVQVSIQFTQAGVFETVWQVKFYNYNKRDHCQWGNSFNSIEYECKPNDTHTLMWINKEMFL", "length": 162, "header": "tr|E9QJH9-1|E9QJH9_DANRE Isoform 1 of CB1 cannabinoid receptor-interacting protein 1b OS=Danio rerio OX=7955 GN=cnrip1b PE=4 SV=1 CANONICAL=E9QJH9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Zebrafish: a model for the study of addiction genetics.", "journal": "Hum. Genet.", "date": "2012", "authors": "Klee Eric W, Schneider Henning, Clark Karl J, Cousin Margot A, Ebbert Jon O, Hooten W Michael, Karpyak Victor M, Warner David O, Ekker Stephen C", "evidence": [ { "database": "UniProtKB", "id": "E9QJH9", "url": "https://www.uniprot.org/uniprotkb/E9QJH9" } ], "reference": [ { "type": "PubMed", "id": "22207143", "url": "https://glygen.org/publication/PubMed/22207143" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E9QJH9", "url": "https://www.uniprot.org/uniprotkb/E9QJH9" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Characterization of bovine A20 gene: Expression mediated by NF-kappaB pathway in MDBK cells infected with bovine viral diarrhea virus-1.", "journal": "Gene", "date": "2016", "authors": "Fredericksen Fernanda, Villalba Melina, Olavarr\u00eda V\u00edctor H", "evidence": [ { "database": "UniProtKB", "id": "E9QJH9", "url": "https://www.uniprot.org/uniprotkb/E9QJH9" } ], "reference": [ { "type": "PubMed", "id": "26809100", "url": "https://glygen.org/publication/PubMed/26809100" } ] }, { "title": "The Cannabinoid Receptor Interacting Proteins 1 of zebrafish are not required for morphological development, viability or fertility.", "journal": "Sci. Rep.", "date": "2017", "authors": "Fin Laura, Bergamin Giorgia, Steiner Roberto A, Hughes Simon M", "evidence": [ { "database": "UniProtKB", "id": "E9QJH9", "url": "https://www.uniprot.org/uniprotkb/E9QJH9" }, { "database": "RefSeq", "id": "NP_001314699", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314699" } ], "reference": [ { "type": "PubMed", "id": "28687732", "url": "https://glygen.org/publication/PubMed/28687732" } ] }, { "title": "New Insights into the Identity of the DFNA58 Gene.", "journal": "Genes (Basel)", "date": "2022", "authors": "Nascimento Larissa Reis do, Vieira-Silva Gleiciele Alice, Kitajima Jo\u00e3o Paulo Fumio Whitaker, Batissoco Ana Carla, Lezirovitz Karina", "evidence": [ { "database": "UniProtKB", "id": "E9QJH9", "url": "https://www.uniprot.org/uniprotkb/E9QJH9" } ], "reference": [ { "type": "PubMed", "id": "36553541", "url": "https://glygen.org/publication/PubMed/36553541" } ] } ], "pathway": [ { "id": "dre:556881", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556881", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1BU35-1", "protein_name": "CB1 cannabinoid receptor-interacting protein 1", "gene_name": "CNRIP1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVDIPSLVKISVALKIQPNDGAVYFKVDGQRFGQNRTIKLLTGAKYKIEVALRPGTVQATTMGIGGVNVPLEEKSRDAQVASYTGIYDTEGVPHTKSGERQPIQVNMQFNDIGVFETVWQVKFYNYHKRDHCQWGNSFGSIEYECKPNETRSLMWINKETFH", "length": 162 }, "evidence": [ { "id": "E9QJH9", "url": "https://omabrowser.org/oma/group/E9QJH9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3HEF9-1", "protein_name": "CB1 cannabinoid receptor-interacting protein 1", "gene_name": "Cnrip1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGDLPGLVRLSIALRIQPNDGPVFFKVDGQRFGQNRTIKLLTGSSYKVEVKIKPTTLQVENISIGGVLVPLELKCKEPDGERVVYTGIYDTEGVAPTKSGERQPIQITMPFTDIGTFETVWQVKFYNYHKRDHCQWGSPFSVIEYECKPNETRSLMWVNKESFL", "length": 164 }, "evidence": [ { "id": "E9QJH9", "url": "https://omabrowser.org/oma/group/E9QJH9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q17QM9-1", "protein_name": "CB1 cannabinoid receptor-interacting protein 1", "gene_name": "CNRIP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPTTLQVENISIGGVVVPLELKSKEPDGDRIVYTGTYDTEGVAPTKSGERQPIQITMPFTDIGTFETMWQVKFYNYHKRDHCQWGSPFSVIEYECKPNETRSLMWVNKESFL", "length": 164 }, "evidence": [ { "id": "E9QJH9", "url": "https://omabrowser.org/oma/group/E9QJH9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5M7A7-1", "protein_name": "CB1 cannabinoid receptor-interacting protein 1", "gene_name": "Cnrip1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDLPGIVRLSIALRIQPNDGPVFFKVDGQRFGQNRTIKLLTGSSYKVEVKIKPTTLQVENISIGGVLVPLELKCKEPDGERVVYTGIYDTEGVAPTKSGERQPIQITMPFTDIGTFETVWQVKFYNYHKRDHCQWGSPFSVIEYECKPNETRSLMWVNKESFL", "length": 164 }, "evidence": [ { "id": "HGNC:24546", "url": "https://alliancegenome.org/gene/HGNC:24546#orthology", "database": "AGR" }, { "id": "MGI:1917505", "url": "https://alliancegenome.org/gene/MGI:1917505#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5M8N0-1", "protein_name": "CB1 cannabinoid receptor-interacting protein 1", "gene_name": "Cnrip1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGDLPGLVRLSIALRIQPNDGPVFFKVDGQRFGQNRTIKLLTGSSYKVEVKIKPTTLQVENISIGGVLVPLELKGKEPDGERVVYTGIYDTEGVAPTKSGERQPIQITMPFTDIGTFETVWQVKFYNYHKRDHCQWGSPFSVIEYECKPNETRSLMWVNKESFL", "length": 164 }, "evidence": [ { "id": "HGNC:24546", "url": "https://alliancegenome.org/gene/HGNC:24546#orthology", "database": "AGR" }, { "id": "MGI:1917505", "url": "https://alliancegenome.org/gene/MGI:1917505#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080722-33", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080722-33#orthology", "database": "AGR" }, { "id": "E9QJH9", "url": "https://omabrowser.org/oma/group/E9QJH9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96F85-1", "protein_name": "CB1 cannabinoid receptor-interacting protein 1", "gene_name": "CNRIP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGDLPGLVRLSIALRIQPNDGPVFYKVDGQRFGQNRTIKLLTGSSYKVEVKIKPSTLQVENISIGGVLVPLELKSKEPDGDRVVYTGTYDTEGVTPTKSGERQPIQITMPFTDIGTFETVWQVKFYNYHKRDHCQWGSPFSVIEYECKPNETRSLMWVNKESFL", "length": 164 }, "evidence": [ { "id": "HGNC:24546", "url": "https://alliancegenome.org/gene/HGNC:24546#orthology", "database": "AGR" }, { "id": "MGI:1917505", "url": "https://alliancegenome.org/gene/MGI:1917505#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080722-33", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080722-33#orthology", "database": "AGR" }, { "id": "E9QJH9", "url": "https://omabrowser.org/oma/group/E9QJH9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E9QJH9", "url": "https://www.uniprot.org/uniprotkb/E9QJH9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "type 1 cannabinoid receptor binding", "id": "GO:0031718", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031718", "evidence": [ { "database": "UniProtKB", "id": "E9QJH9", "url": "https://www.uniprot.org/uniprotkb/E9QJH9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F7J2-1", "uniprot_ac": "E7F7J2", "uniprot_id": "E7F7J2_DANRE", "mass": { "chemical_mass": 50778.0, "monoisotopic_mass": 50778.0 }, "refseq": { "ac": "XP_706561", "name": "tubulin epsilon and delta complex protein 1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706561" }, "gene_names": [ { "name": "tedc1", "type": "recommended", "evidence": [ { "id": "E7F7J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F7J2" } ] }, { "name": "tedc1", "type": "synonym", "evidence": [ { "id": "XP_706561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706561" } ] } ], "protein_names": [ { "name": "Tubulin epsilon and delta complex protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F7J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F7J2/entry#names_and_taxonomy" } ] }, { "name": "tubulin epsilon and delta complex protein 1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_706561", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706561" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_706561.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_706561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706561" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F7J2", "url": "https://www.uniprot.org/uniprotkb/E7F7J2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tedc1", "url": "https://www.uniprot.org/uniprotkb/E7F7J2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131121-397", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-397", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000091366", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000091366", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "570574", "url": "https://www.ncbi.nlm.nih.gov/gene/570574", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027996", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027996", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570574", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570574", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FWTWMDS", "url": "https://omabrowser.org/oma/group/FWTWMDS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2B5P4", "url": "https://www.orthodb.org/?gene=A0A8M2B5P4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7F7J2", "url": "https://www.orthodb.org/?gene=E7F7J2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35076", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35076", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35076:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35076:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14970", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14970", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_706561", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_706561", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B5P4", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B5P4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B5P4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B5P4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F7J2", "url": "https://www.uniprot.org/uniprotkb/E7F7J2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F7J2-1", "url": "https://www.uniprot.org/uniprotkb/E7F7J2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131121-397", "url": "https://zfin.org/ZDB-GENE-131121-397", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MQRTKSVKVKEVITSLCKLLSGLNVESIPTAETFRRAKFNRKDAVVDMWSLLNRLLQRAFALDCACRDSKHQEFDTQLLFVRSALCYCGYGAPWVVEPRPTSHIEEMESRDLLLALGWLLASGNLLDFLLAEKVYQLDTLSSAPTIPQGPISGLDDLMACGSGEELTVKKDQEIQALQWQYGKLRLQWKSLLSAQEERSKFTHRVISSISSSAVRHPHATGSHQTNMTSTALDKDLERIQALNEILEAYLDWKLHEPLFWCWMDSVMDSSLTDASEVKPAVWPPGGQTVTATCPHGDKTRRAVRQLDKMLLRLQTELRARRIEQATLALASQGGHQGASRLSDRQRMEVEKTVAGYLEGLRLSNTSAITSKGFVPCLQDPQPTKPPRRFHSAEPGLAVTAGKLQASTVLGELREREAVLQWQLERLRQSMRVELQRQASTMEGVILIPPIKR", "length": 452, "header": "tr|E7F7J2-1|E7F7J2_DANRE Isoform 1 of Tubulin epsilon and delta complex protein 1 isoform X1 OS=Danio rerio OX=7955 GN=tedc1 PE=4 SV=1 CANONICAL=E7F7J2-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B5P4-1", "url": "https://www.uniprot.org/uniprotkb/E7F7J2/entry#A0A8M2B5P4-1", "sequence": { "sequence": "MQRTKSVKVKEVITSLCKLLSGLNVESIPTAETFRRAKFNRKDAVVDMWSLLNRLLQRAFALDCACRDSKHQEFDTQLLFVRSALCYCGYGAPWVVEPRPTSHIEEMESRDLLLALGWLLASGNLLDFLLAEKVYQLDTLSSAPTIPQGPISGLDDLMACGSGEELTVKKDQEIQALQWQYGKLRLQWKSLLSAQEERSKFTHRDLERIQALNEILEAYLDWKLHEPLFWCWMDSVMDSSLTDASEVKPAVWPPGGQTVTATCPHGDKTRRAVRQLDKMLLRLQTELRARRIEQATLALASQGGHQGASRLSDRQRMEVEKTVAGYLEGLRLSNTSAITSKGFVPCLQDPQPTKPPRRFHSAEPGLAVTAGKLQASTVLGELREREAVLQWQLERLRQSMRVELQRQASTMEGVILIPPIKR", "length": 422, "header": "tr|A0A8M2B5P4-1|E7F7J2_DANRE Computationally mapped isoform of Tubulin epsilon and delta complex protein 1 isoform X1 OS=Danio rerio OX=7955 GN=tedc1 PE=4 SV=1 CANONICAL=E7F7J2-1" }, "locus": {} }, { "isoform_ac": "E7F7J2-1", "url": "https://www.uniprot.org/uniprotkb/E7F7J2/entry#E7F7J2-1", "sequence": { "sequence": "MQRTKSVKVKEVITSLCKLLSGLNVESIPTAETFRRAKFNRKDAVVDMWSLLNRLLQRAFALDCACRDSKHQEFDTQLLFVRSALCYCGYGAPWVVEPRPTSHIEEMESRDLLLALGWLLASGNLLDFLLAEKVYQLDTLSSAPTIPQGPISGLDDLMACGSGEELTVKKDQEIQALQWQYGKLRLQWKSLLSAQEERSKFTHRVISSISSSAVRHPHATGSHQTNMTSTALDKDLERIQALNEILEAYLDWKLHEPLFWCWMDSVMDSSLTDASEVKPAVWPPGGQTVTATCPHGDKTRRAVRQLDKMLLRLQTELRARRIEQATLALASQGGHQGASRLSDRQRMEVEKTVAGYLEGLRLSNTSAITSKGFVPCLQDPQPTKPPRRFHSAEPGLAVTAGKLQASTVLGELREREAVLQWQLERLRQSMRVELQRQASTMEGVILIPPIKR", "length": 452, "header": "tr|E7F7J2-1|E7F7J2_DANRE Isoform 1 of Tubulin epsilon and delta complex protein 1 isoform X1 OS=Danio rerio OX=7955 GN=tedc1 PE=4 SV=1 CANONICAL=E7F7J2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 399, "start_aa": "Thr", "end_pos": 399, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr399", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:570574", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570574", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZZB2-1", "protein_name": "Tubulin epsilon and delta complex 1", "gene_name": "Tedc1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRRRSRVEGAARALPEAVAALSRSLPAGPSPEIFRRAKFDRPEAAPVLWQLLLRVLSPLAANNTWTDLAPEAQARVVKSALGSRGYPRSVLLQFPDGSSQGSRELLLALSWLLAQGPLLEQLLAQTRVQVGDQLPQCEALTSPGPLACLVATKSPVDLRLVEWLMGKLRFRWRCLILSQREQCTLLSKIHLYTQGCHSQQSLGHLSVAETEMLRDPESSQQLLHALESENARLEAALEWRRCELVFWQWMDTVLDACSPETPAVTSQPTALPMISEGGLGELESVRQELLALQEELREVAEPRRAAWESRVGGLGQGPEWSNSRKALREVVERELADLQGSWKLCSTPAQPQRPHRLVRSKDGAPRRQGLQAAEVIRTLSAKEDCLKKALHQLQCQCQQELARLAGTLPGLIWVLPPGH", "length": 420 }, "evidence": [ { "id": "HGNC:20127", "url": "https://alliancegenome.org/gene/HGNC:20127#orthology", "database": "AGR" }, { "id": "MGI:2144738", "url": "https://alliancegenome.org/gene/MGI:2144738#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UK37-1", "protein_name": "Tubulin epsilon and delta complex protein 1", "gene_name": "Tedc1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRRRSRVEGAARALPEAVAALSRCLPAGPSPEIFRRAKFDRPEAAPVLWQLLLRVLSPLAANNTWTDLAPEAQACVVKSALGSQGYPRSVLLQFPDGSSQGSRELLLALSWLLARGPLLEQLLAQTRVQLGDQLPQWEAPTSPGPPAPFVEPKSPVDLRLVEWLMGRLRFRWRCLISSQQEQCILLSKIHLYTQGCHSQQSLGHLSVAETEMLRDPESGQQLLQALESENIRLEAALEWRRRELVFWQWMDTVLDTCSPETPAVTSQPTFLPEISEGGLGELESVKQELQALQEELREVSEPRRAAWEARVGGLGQGPEWSNSRKALQEAVQQELAALQGSWEQSSTPGQPQRPHRLVRSKDGAPRPQGLQAAEVIRTLSAKEACLKKALHQLQRQCQQELARLAGALPGLIWILPPEH", "length": 420 }, "evidence": [ { "id": "HGNC:20127", "url": "https://alliancegenome.org/gene/HGNC:20127#orthology", "database": "AGR" }, { "id": "MGI:2144738", "url": "https://alliancegenome.org/gene/MGI:2144738#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-397", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-397#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q86SX3-1", "protein_name": "Tubulin epsilon and delta complex protein 1", "gene_name": "TEDC1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGRRRQRVDPAAGARAGALPEAIAALSRSLPSGPSPEIFRRAKFDRPEATSALWQLLFRVLSPLPAGNALASLALEVQARLVKSALCSQGYPRLALAQLPEDGSQGSRELLLALSWLLARGPVPEQMLAQARVPLGDEMTVCQCEALASPGPPAPHMEAEGPVDVRHVQWLMGKLRFRWRQLVSSQQEQCALLSKIHLYTRGCHSDQSLSHLSVTEAEMLRDPEGGQQVSGAGAAQNLDLAYPKCLHSFCTPGMGPRTFWNDLWLVCEQPGLLPGDWAAPLDPGGASACSLLSPFRALLRTLERENQRLEAVLAWRRSELVFWRWMDTVLGTCAPEVPAAASQPTFLPWVPERGGGELDLVVRELQALEEELREAAERRRAAWEAKAGGCGRGPEWSAARRASREAVEKELGALQQCWERDGGPAQPHGPHRLVRREDGAAGDRDLRAAVVIRTLRSQEACLEAVLRRLQGQCRQELARLVGARPGLIWIPPPGR", "length": 495 }, "evidence": [ { "id": "HGNC:20127", "url": "https://alliancegenome.org/gene/HGNC:20127#orthology", "database": "AGR" }, { "id": "MGI:2144738", "url": "https://alliancegenome.org/gene/MGI:2144738#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-131121-397", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-397#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 226, "end_pos": 228, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F7J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F7J2" }, { "id": "PF14970", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14970" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tubulin epsilon and delta complex protein 1", "eco_id": "ECO_0000259", "start_pos": 102, "end_pos": 268, "start_aa": "Ser", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 399 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 226, "end_pos": 228 }, { "start_pos": 364, "end_pos": 366 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E9QCF8-1", "uniprot_ac": "E9QCF8", "uniprot_id": "E9QCF8_DANRE", "mass": { "chemical_mass": 38034.0, "monoisotopic_mass": 38034.0 }, "refseq": { "ac": "NP_001316803", "name": "ELMO domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316803" }, "gene_names": [ { "name": "elmod1", "type": "recommended", "evidence": [ { "id": "E9QCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QCF8" } ] }, { "name": "elmod1", "type": "synonym", "evidence": [ { "id": "NP_001316803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316803" } ] }, { "name": "zgc:158733", "type": "synonym", "evidence": [ { "id": "NP_001316803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316803" }, { "id": "E9QCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QCF8" } ] } ], "protein_names": [ { "name": "ELMO domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001316803", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316803" }, { "id": "E9QCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QCF8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588719.14893683.1, SRR32588723.3305879.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505371, SAMEA3505381 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Aug 4, 2016 this sequence version replaced XP_005161265.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001316803", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316803" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QCF8", "url": "https://www.uniprot.org/uniprotkb/E9QCF8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "elmod1", "url": "https://www.uniprot.org/uniprotkb/E9QCF8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070112-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-262", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000062056", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000062056", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "791199", "url": "https://www.ncbi.nlm.nih.gov/gene/791199", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006816", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006816", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050868", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050868", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:791199", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:791199", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PHFQQTF", "url": "https://omabrowser.org/oma/group/PHFQQTF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8M2B852", "url": "https://www.orthodb.org/?gene=A0A8M2B852", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "A0A8M9P3G2", "url": "https://www.orthodb.org/?gene=A0A8M9P3G2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E9QCF8", "url": "https://www.orthodb.org/?gene=E9QCF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12771", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12771", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12771:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12771:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04727", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04727", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001316803", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001316803", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M2B852", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B852", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M2B852-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M2B852-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P3G2", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9P3G2-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9P3G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCU3", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCU3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PCU3-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PCU3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QCF8", "url": "https://www.uniprot.org/uniprotkb/E9QCF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QCF8-1", "url": "https://www.uniprot.org/uniprotkb/E9QCF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070112-262", "url": "https://zfin.org/ZDB-GENE-070112-262", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKHFLRVLTQFLVFLYCKCLWRGLKFVIRKVTGRCELQRICYNNKPGARRTLKIESSLRCSKHELLQSAISVHPDSVEKSIDDIMALKKINLDTNPQLGISLQACLLQIVGYRNLVVEVEKLRREPYDCENPAHEEMLMKLWKELRPDSPLSGRISKQWCEIGFQGNDPKTDFRGMGLLGLHNLLYFAEHDKATALQVLHDSLQPKHSKMSKAEWEKKKFDKAIGYSFAIVGINITDLAYSLLVSGALKTHLYNVAPEMPSLVHFQQTFCYLMQEFHRFWMEEDPCDIMEFNRVRTKFYKRVLKQLKNPDMALCPHFTASDLHLVNL", "length": 327, "header": "tr|E9QCF8-1|E9QCF8_DANRE Isoform 1 of ELMO domain-containing protein 1 OS=Danio rerio OX=7955 GN=elmod1 PE=4 SV=1 CANONICAL=E9QCF8-1" }, "isoforms": [ { "isoform_ac": "A0A8M2B852-1", "url": "https://www.uniprot.org/uniprotkb/E9QCF8/entry#A0A8M2B852-1", "sequence": { "sequence": "MKHFLRVLTQFLVFLYCKCLWRGLKFVIRKVTGRCELQRICYNNKPGARRTLKIESSLRCSKHELLQSAISVHPDSVEKSIDDIMALKKINLDTNPQLGISLQACLLQIVGYRNLVVEVEKLRREPYDCENPAHEEMLMKLWKELRPDSPLSGRISKQWCEIGFQGNDPKTDFRGMGLLGLHNLLYFAEHDKATALQVLHDSLQPKHRDVSKEEASKMSKAEWEKKKFDKAIGYSFAIVGINITDLAYSLLVSGALKTHLYNVAPEMPSLVHFQQTFCYLMQEFHRFWMEEDPCDIMEFNRVRTKFYKRVLKQLKNPDMALCPHFTASDLHLVNL", "length": 335, "header": "tr|A0A8M2B852-1|E9QCF8_DANRE Computationally mapped isoform of ELMO domain-containing protein 1 OS=Danio rerio OX=7955 GN=elmod1 PE=4 SV=1 CANONICAL=E9QCF8-1" }, "locus": {} }, { "isoform_ac": "A0A8M9P3G2-1", "url": "https://www.uniprot.org/uniprotkb/E9QCF8/entry#A0A8M9P3G2-1", "sequence": { "sequence": "MPMGRRVYPVSSNSQRNQQLDSNRVLTQFLVFLYCKCLWRGLKFVIRKVTGRCELQRICYNNKPGARRTLKIESSLRCSKHELLQSAISVHPDSVEKSIDDIMALKKINLDTNPQLGISLQACLLQIVGYRNLVVEVEKLRREPYDCENPAHEEMLMKLWKELRPDSPLSGRISKQWCEIGFQGNDPKTDFRGMGLLGLHNLLYFAEHDKATALQVLHDSLQPKHRDVSKEEASKMSKAEWEKKKFDKAIGYSFAIVGINITDLAYSLLVSGALKTHLYNVAPEMPSLVHFQQTFCYLMQEFHRFWMEEDPCDIMEFNRVRTKFYKRVLKQLKNPDMALCPHFTASDLHLVNL", "length": 353, "header": "tr|A0A8M9P3G2-1|E9QCF8_DANRE Computationally mapped isoform of ELMO domain-containing protein 1 OS=Danio rerio OX=7955 GN=elmod1 PE=4 SV=1 CANONICAL=E9QCF8-1" }, "locus": {} }, { "isoform_ac": "A0A8M9PCU3-1", "url": "https://www.uniprot.org/uniprotkb/E9QCF8/entry#A0A8M9PCU3-1", "sequence": { "sequence": "MPMGRRVYPVSSNSQRNQQLDSNRVLTQFLVFLYCKCLWRGLKFVIRKVTGRCELQRICYNNKPGARRTLKIESSLRCSKHELLQSAISVHPDSVEKSIDDIMALKKINLDTNPQLGISLQACLLQIVGYRNLVVEVEKLRREPYDCENPAHEEMLMKLWKELRPDSPLSGRISKQWCEIGFQGNDPKTDFRGMGLLGLHNLLYFAEHDKATALQVLHDSLQPKHSKMSKAEWEKKKFDKAIGYSFAIVGINITDLAYSLLVSGALKTHLYNVAPEMPSLVHFQQTFCYLMQEFHRFWMEEDPCDIMEFNRVRTKFYKRVLKQLKNPDMALCPHFTASDLHLVNL", "length": 345, "header": "tr|A0A8M9PCU3-1|E9QCF8_DANRE Computationally mapped isoform of ELMO domain-containing protein 1 OS=Danio rerio OX=7955 GN=elmod1 PE=4 SV=1 CANONICAL=E9QCF8-1" }, "locus": {} }, { "isoform_ac": "E9QCF8-1", "url": "https://www.uniprot.org/uniprotkb/E9QCF8/entry#E9QCF8-1", "sequence": { "sequence": "MKHFLRVLTQFLVFLYCKCLWRGLKFVIRKVTGRCELQRICYNNKPGARRTLKIESSLRCSKHELLQSAISVHPDSVEKSIDDIMALKKINLDTNPQLGISLQACLLQIVGYRNLVVEVEKLRREPYDCENPAHEEMLMKLWKELRPDSPLSGRISKQWCEIGFQGNDPKTDFRGMGLLGLHNLLYFAEHDKATALQVLHDSLQPKHSKMSKAEWEKKKFDKAIGYSFAIVGINITDLAYSLLVSGALKTHLYNVAPEMPSLVHFQQTFCYLMQEFHRFWMEEDPCDIMEFNRVRTKFYKRVLKQLKNPDMALCPHFTASDLHLVNL", "length": 327, "header": "tr|E9QCF8-1|E9QCF8_DANRE Isoform 1 of ELMO domain-containing protein 1 OS=Danio rerio OX=7955 GN=elmod1 PE=4 SV=1 CANONICAL=E9QCF8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2002", "authors": "Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA", "evidence": [ { "database": "UniProtKB", "id": "E9QCF8", "url": "https://www.uniprot.org/uniprotkb/E9QCF8" } ], "reference": [ { "type": "PubMed", "id": "12477932", "url": "https://glygen.org/publication/PubMed/12477932" } ] } ], "pathway": [ { "id": "dre:791199", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:791199", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A7Y9-1", "protein_name": "ELMO domain containing 1", "gene_name": "ELMOD1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKHFLRMLIQVCLYFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIEDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRREPYDSENPQHEEMLLQLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDAAGAQQVLSDSLHPKCSKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 326 }, "evidence": [ { "id": "E9QCF8", "url": "https://omabrowser.org/oma/group/E9QCF8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6GJG9-1", "protein_name": "ELMO domain containing 1", "gene_name": "Elmod1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGDSQSLHLLVLRMPENLTAVNGEKRMSLKLSFCQLLTQLSIGRVLSFVPHRMLIQVCLYFYCKFLWRCMKFVMRKLTGRCELQRICYGTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRREPYDSDNPQHEEMLLKLWEFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDATVAQQVLCDSVHPKCSKFSKTEWEKKKMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 372 }, "evidence": [ { "id": "HGNC:25334", "url": "https://alliancegenome.org/gene/HGNC:25334#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-262#orthology", "database": "AGR" }, { "id": "RGD:1564186", "url": "https://alliancegenome.org/gene/RGD:1564186#orthology", "database": "AGR" }, { "id": "MGI:3583900", "url": "https://alliancegenome.org/gene/MGI:3583900#orthology", "database": "AGR" }, { "id": "FB:FBgn0037473", "url": "https://alliancegenome.org/gene/FB:FBgn0037473#orthology", "database": "AGR" }, { "id": "E9QCF8", "url": "https://omabrowser.org/oma/group/E9QCF8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1P1T7-1", "protein_name": "ELMO domain-containing protein 2 precursor", "gene_name": "elmod2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLGYIWQCFYSSCLRFWLKWFLRLVTGRCELQRICARCKAGALRTSQIEYSLKSSKSKVLQTALSVKQNELEDRLAQIIQEKRIKEQKDPTFKVNLRQCLLQINGYNELFEEVEELRKKVFDSENEQHENMLLKLWDLLMPSVKLESRITKQWGNIGFQGDDPKTDFRGMGMLGLTNLLFFSEKHTDAARQVLSHANHPTLGYSYAIVGINLTEMAYSLMKSDALKLHFYNSVSGKAEMQHFHQFYCYLAYEFDKFWLQEEPESIMEFNRYREKFHDKVKGHLQEPEVTLTLTPNPEN", "length": 298 }, "evidence": [ { "id": "FB:FBgn0037473", "url": "https://alliancegenome.org/gene/FB:FBgn0037473#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0XPZ9-1", "protein_name": "ELMO domain containing 1", "gene_name": "ELMOD1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKHFLRMFIQVCLYFYCKCLWRCLKFVVRKLTGRCELQRICYNTKPGAARTMKIEASLKGSKSKRLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGVSLQACLLQIVGYRNLIVEVEKLRREPYDSENLQHEEMLLKLWKCLKPNSPLKARISKQWCEIGFQGDDPKTDFRGMGLLGLYNLVYFAEWDTEVAQQVLSDSLHPKYSQFSKVEWEKKKFDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNVAPEAPTLTHFQQTFCYLMHEFHKFWIEEDPLDIMEFNRVREKFHKRILKQLQNPEMALCPHFAASESLINM", "length": 326 }, "evidence": [ { "id": "E9QCF8", "url": "https://omabrowser.org/oma/group/E9QCF8/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZNV6-1", "protein_name": "ELMO domain containing 2", "gene_name": "Elmod2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFLSLWEFFYGHFFRFWMKWVLRQMTGKCELQRIFDTYGGAQRTYRIENSLTYSKSKVLQNATRVAESDLDRCIVDIMKEKKICPEKDSSFQICMRTCLLQITGYRQLYHDVENVRKKPYDSANAQHEKLLLKLWSLLMPTKKLKARISKQWADIGFQGDDPKTDFRGMGILGLINLVYFSENYTSEAHQILSRSNHPKLGYSYAIVGINLTEMAYSLLKSEALKLHLYNFVPGVPTMEHFHQFYCYLVYEFDKFWLEEEPESIMYFNLYREKFHERIKGLLMDCNAVLTLKT", "length": 293 }, "evidence": [ { "id": "FB:FBgn0037473", "url": "https://alliancegenome.org/gene/FB:FBgn0037473#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0IIE6-1", "protein_name": "ELMO domain-containing protein 1", "gene_name": "ELMOD1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKHFLRMLIQVCLFFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRRESYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDAAAAQQVLSDSLHPKCSKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 326 }, "evidence": [ { "id": "E9QCF8", "url": "https://omabrowser.org/oma/group/E9QCF8/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q3V1U8-1", "protein_name": "ELMO domain-containing protein 1", "gene_name": "Elmod1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKHFLRMLIQVCLYFYCKFLWRCMKFVMRKLTGRCELQRICYGTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIDDIMELKKINPDINPQLGISLQACLLQIVGYRNLIADVEKLRREPYDSDNPQHEEMLLKLWELLKPNTPLESRVSKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDATVAQQVLSDSVHPKCSKFSKIEWEKKKMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 326 }, "evidence": [ { "id": "HGNC:25334", "url": "https://alliancegenome.org/gene/HGNC:25334#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-262#orthology", "database": "AGR" }, { "id": "RGD:1564186", "url": "https://alliancegenome.org/gene/RGD:1564186#orthology", "database": "AGR" }, { "id": "MGI:3583900", "url": "https://alliancegenome.org/gene/MGI:3583900#orthology", "database": "AGR" }, { "id": "FB:FBgn0037473", "url": "https://alliancegenome.org/gene/FB:FBgn0037473#orthology", "database": "AGR" }, { "id": "E9QCF8", "url": "https://omabrowser.org/oma/group/E9QCF8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BGF6-1", "protein_name": "ELMO domain-containing protein 2", "gene_name": "Elmod2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFVSLWEFFYGHFFRFWMKWLLRQMTGKCELQRIFDTYGGAQRTYRIENSLTYSKNKVLQNATRVAQSELDRCIANIMKEKNICSEKDTSFQICMRTCLLQITGYKQLYHDVENVRKKPYDSANAQHEKMLLKLWSLLMPTKKLTARISKQWADIGFQGDDPKTDFRGMGILGLINLVYFSENYTSEAHQILSRSNHPKLGYSYAIVGINLTEMAYSLLKSEALKLHLYNFVPGVPTMEHFHQFYCYLVYEFDKFWLEEEPESIMYFNLYREKFHERIKGLLMDCNAVLTLKT", "length": 293 }, "evidence": [ { "id": "FB:FBgn0037473", "url": "https://alliancegenome.org/gene/FB:FBgn0037473#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IZ81-1", "protein_name": "ELMO domain-containing protein 2", "gene_name": "ELMOD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFISLWEFFYGHFFRFWMKWLLRQMTGKCELQRIFDTYVGAQRTHRIENSLTYSKNKVLQKATHVVQSEVDKYVDDIMKEKNINPEKDASFKICMKMCLLQITGYKQLYLDVESVRKRPYDSDNLQHEELLMKLWNLLMPTKKLNARISKQWAEIGFQGDDPKTDFRGMGILGLINLVYFSENYTSEAHQILSRSNHPKLGYSYAIVGINLTEMAYSLLKSEALKFHLYNLVPGIPTMEHFHQFYCYLVYEFDKFWFEEEPESIMYFNLYREKFHEKIKGLLLDCNVALTLKV", "length": 293 }, "evidence": [ { "id": "FB:FBgn0037473", "url": "https://alliancegenome.org/gene/FB:FBgn0037473#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8N336-1", "protein_name": "ELMO domain-containing protein 1", "gene_name": "ELMOD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKHFLRMLIQVCLYFYCKFLWRCLKFVMRKLTGRCELQRICYNTKPGASRTMKIETSLRDSKSKLLQTSVSVHPDAIEKTIEDIMELKKINPDVNPQLGISLQACLLQIVGYRNLIADVEKLRREAYDSDNPQHEEMLLKLWKFLKPNTPLESRISKQWCEIGFQGDDPKTDFRGMGLLGLYNLQYFAERDATAAQQVLSDSLHPKCRDITKEEISKFSKAEWEKKRMDKAIGYSFAIVGINITDLAYNLLVSGALKTHFYNIAPEAPTLSHFQQTFCYLMHEFHKFWIEEDPMDIMEFNRVREKFRKRIIKQLQNPDMALCPHFAASEGLINM", "length": 334 }, "evidence": [ { "id": "HGNC:25334", "url": "https://alliancegenome.org/gene/HGNC:25334#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-262#orthology", "database": "AGR" }, { "id": "RGD:1564186", "url": "https://alliancegenome.org/gene/RGD:1564186#orthology", "database": "AGR" }, { "id": "MGI:3583900", "url": "https://alliancegenome.org/gene/MGI:3583900#orthology", "database": "AGR" }, { "id": "FB:FBgn0037473", "url": "https://alliancegenome.org/gene/FB:FBgn0037473#orthology", "database": "AGR" }, { "id": "E9QCF8", "url": "https://omabrowser.org/oma/group/E9QCF8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VI65-1", "protein_name": "ELMO domain-containing protein", "gene_name": "Elmod", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFILDRILPFIFSYIRPFIKWFLHAFTRLSELQRICYGAKAGASRTSQVERSLTLSKRPQIRRLVLDLDEAAPYVSNAELLDFAPRAARIVMQAKRIKNNVHPDFARLFGTCVTSIWGYRRLMHQVEQLRAEKYDSDNLDHEQKLLRLWQLLMPDTPLTGRVTKQWQDIGFQGDDPKTDFRGMGMLGLENLLYFATAYNDAAKHVLLHSMHPTLGYTYAIVGINLTSMAFNLVKTGAAKTHFYNLVVQHRQDFSTVEDFHKLYCYLFFEFDRFWMESDPRNIMDFREIYQSFEITKLEALHNDSTIFKTNLVVESV", "length": 316 }, "evidence": [ { "id": "HGNC:25334", "url": "https://alliancegenome.org/gene/HGNC:25334#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-262", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-262#orthology", "database": "AGR" }, { "id": "RGD:1564186", "url": "https://alliancegenome.org/gene/RGD:1564186#orthology", "database": 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"domain_list": [ { "evidence": [ { "id": "E9QCF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QCF8" }, { "id": "PS51335", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51335" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "ELMO", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 306, "start_aa": "Ala", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 234, "end_pos": 236 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1Q795-1", "uniprot_ac": "F1Q795", "uniprot_id": "F1Q795_DANRE", "mass": { "chemical_mass": 176280.0, "monoisotopic_mass": 176280.0 }, "refseq": { "ac": "XP_021325303", "name": "sterile alpha motif domain-containing protein 9-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325303" }, "gene_names": [ { "name": "samd9l", "type": "recommended", "evidence": [ { "id": "F1Q795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q795" } ] }, { "name": "samd9l", "type": "synonym", "evidence": [ { "id": "XP_021325303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325303" } ] } ], "protein_names": [ { "name": "Sterile alpha motif domain-containing protein 9-like", "type": "synonym", "evidence": [ { "id": "F1Q795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q795/entry#names_and_taxonomy" } ] }, { "name": "sterile alpha motif domain-containing protein 9-like", "type": "synonym", "evidence": [ { "id": "XP_021325303", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325303" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021325303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325303" } ] } ], "disease": [ { "disease_id": "DOID:0050908", "recommended_name": { "id": "DOID:0050908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050908", "name": "myelodysplastic syndrome", "description": "A bone marrow cancer that is characterized by under production of white blood cells, red blood cells and platelets." }, "synonyms": [ { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic syndrome", "description": "A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001)" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "MDS", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "MDS, unclassifiable", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "MDS-U", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "Myelodysplastic Syndromes", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "dysmyelopoietic syndrome", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "hematopoeitic - myelodysplastic syndrome (MDS)", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplasia", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic neoplasm", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic syndrome", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic syndrome, somatic", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic syndrome, unclassifiable", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic syndrome/neoplasm", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "myelodysplastic syndromes", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "oligoblastic leukaemia", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "oligoblastic leukemia", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "preleukemia", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "smoldering leukemia", "description": "" }, { "id": "MONDO:0018881", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018881", "name": "smouldering leukaemia", "description": "" }, { "id": "MIM:614286", "resource": "MIM", "url": "https://www.omim.org/entry/614286", "name": "Myelodysplastic syndrome", "description": "Myelodysplastic syndrome" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050908" } ] }, { "disease_id": "DOID:1441", "recommended_name": { "id": "DOID:1441", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1441", "name": "autosomal dominant cerebellar ataxia", "description": "A cerebellar ataxia that has_material_basis_in autosomal dominant inheritance." }, "synonyms": [ { "id": "DOID:1441", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1441", "name": "spinocerebellar ataxia", "description": "" }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "spinocerebellar ataxia type 1", "description": "Spinocerebellar ataxia type 1 (SCA1) is a subtype of type I autosomal dominant cerebellar ataxia (ADCA type I) characterized by dysarthria, writing difficulties, limb ataxia, and commonly nystagmus and saccadic abnormalities." }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "ATXN1 autosomal dominant cerebellar ataxia type I", "description": "" }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "SCA1", "description": "" }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "Sca1", "description": "" }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "autosomal dominant cerebellar ataxia type I caused by mutation in ATXN1", "description": "" }, { "id": "MONDO:0008119", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008119", "name": "spinocerebellar 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021325303", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021325303", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1Q795", "url": "https://www.uniprot.org/uniprotkb/F1Q795", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q795-1", "url": "https://www.uniprot.org/uniprotkb/F1Q795-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-738", "url": "https://zfin.org/ZDB-GENE-130530-738", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEKPEDSPMETWTESMVSNWLKSIGIKEAYIEKLHEEEVNGQVLSKVSEEFLKKETGMKAGPALLIIKERNEILKNSQKAQSKPKQPSGKNENGVSKNKVADTRADIKEVDEEDPVPAVLRNRDTKPRPFEMKGGDFKYVKNSVLLPESGVIDMISPCHEYKSFAIAATLDRQRLQAKLAREVLKFATGCMNVRTNGTIHFGVMDSRGDAGHVHGEIVGFPVKEKDIYYDALDYIEKGFSESDSELVRLCIGEPQFVQVICSDSSEEHFIVEVDIKPSVRIVKNQVFSVRLPNFSEEANKVQLEKKTVYRRVGSKTEPVADLMEFYQHVSLRDSQREEAEKMQKFTSPEPSQNLGKKLTMLITGGKKVMDKDKWHILVTNRFQEKDLQSIDFLLNMKIFCVFDFDPDSNVTGLCREYDKHHAVNRHFMQNYKIPSGLSIREFESRERLFDQISWIFCNGRSDFKGSEPHCDEKTWVKTKRTLLKECVSLICKNILPKGTFQVIFLLTSPVDTPLLNTFYEFITDMEGHEDIICLAESEENFKKWQSFALGSSDMETIKQSSVVGMTVSQINATLQRVQPTTTQATKRLPILVKGECFLDTREEKVRSSLEILSLNHCEENSPDVIESEKETIEKQFYHGGKVTWINLWLAEKKIVGEVIQRDAYNEVNELVKECLNWSSERAPISCINIYHHPGSGGSTVARQVLWNYRRDLRCAVVKSSKSVSAVSEDAVWLREYEEKDPQKCLPLLLLFEDCDQEYLEDVKYELEVAVNTKKITRGTLCFILLSCRRSHNPEKMCKESPQHNVAITHKLSEKEKQHFSKKRHSLEKQFKPEFILTFVLMSEEFKSHKIAEYVKQFVKHLLQGIDHNSAVTKLVLYVALLNTYVQNSFLSRSHCEALLALSILVDRFRQHVFETSLSEQARLVLIHLRDENTYITSIRIIHPLVAKEILHQLLGDEQQQSDLALDLLNNDVLFEHRFGKDHYMKFLRDLFMTRHRISKGDESDSFFSPLIEHVRKKECPDKAIDLLKGAYKRFNEDAFFAQHLARLNYKHERFEAAEQWAKTAVAKMPHNSYILDTKGQVYRQWFLAKCKAIKQNETPENTVDPLEMAFKAIECFQACENAAVQDNDTMNNAGFVGVVEVGCALLKLMSNLQVFSRRRRPSELSRYLLTNYIPPEIETPWENFHYKLKNLQKTMLEALEWISEDLSFFQTDLNTDEEKTAETVESTIKHPIHWLVNKSHDYGRYFSGASPGTDKNREKLSPVMKRMMIHYHGGGNITTILFLLTNQKDRDPVPVLEKIISFYPSDPMRAQLPQVDLVNYIASHLALSLLSPESPKLAAFQDLQRMSYQFLKEGQKKSISNANFLLVLLFWPEEQETEVEKERKYKIVLSAVENLQRDYEKRLKDIPPRKKRIYTHFFLSNGTGFEKFVHKSKFETITKLFSVPEKRLKWFSGEVWKMPEMSKLLKCVTGWTEDEKVYLEGPKGMKFHIPALKMSSIPHKNENVTFYLGFTLKGPVAYNITVQTQN", "length": 1526, "header": "tr|F1Q795-1|F1Q795_DANRE Isoform 1 of Sterile alpha motif domain-containing protein 9-like OS=Danio rerio OX=7955 GN=samd9l PE=4 SV=2 CANONICAL=F1Q795-1" }, "isoforms": [ { "isoform_ac": "F1Q795-1", "url": "https://www.uniprot.org/uniprotkb/F1Q795/entry#F1Q795-1", "sequence": { "sequence": "MEKPEDSPMETWTESMVSNWLKSIGIKEAYIEKLHEEEVNGQVLSKVSEEFLKKETGMKAGPALLIIKERNEILKNSQKAQSKPKQPSGKNENGVSKNKVADTRADIKEVDEEDPVPAVLRNRDTKPRPFEMKGGDFKYVKNSVLLPESGVIDMISPCHEYKSFAIAATLDRQRLQAKLAREVLKFATGCMNVRTNGTIHFGVMDSRGDAGHVHGEIVGFPVKEKDIYYDALDYIEKGFSESDSELVRLCIGEPQFVQVICSDSSEEHFIVEVDIKPSVRIVKNQVFSVRLPNFSEEANKVQLEKKTVYRRVGSKTEPVADLMEFYQHVSLRDSQREEAEKMQKFTSPEPSQNLGKKLTMLITGGKKVMDKDKWHILVTNRFQEKDLQSIDFLLNMKIFCVFDFDPDSNVTGLCREYDKHHAVNRHFMQNYKIPSGLSIREFESRERLFDQISWIFCNGRSDFKGSEPHCDEKTWVKTKRTLLKECVSLICKNILPKGTFQVIFLLTSPVDTPLLNTFYEFITDMEGHEDIICLAESEENFKKWQSFALGSSDMETIKQSSVVGMTVSQINATLQRVQPTTTQATKRLPILVKGECFLDTREEKVRSSLEILSLNHCEENSPDVIESEKETIEKQFYHGGKVTWINLWLAEKKIVGEVIQRDAYNEVNELVKECLNWSSERAPISCINIYHHPGSGGSTVARQVLWNYRRDLRCAVVKSSKSVSAVSEDAVWLREYEEKDPQKCLPLLLLFEDCDQEYLEDVKYELEVAVNTKKITRGTLCFILLSCRRSHNPEKMCKESPQHNVAITHKLSEKEKQHFSKKRHSLEKQFKPEFILTFVLMSEEFKSHKIAEYVKQFVKHLLQGIDHNSAVTKLVLYVALLNTYVQNSFLSRSHCEALLALSILVDRFRQHVFETSLSEQARLVLIHLRDENTYITSIRIIHPLVAKEILHQLLGDEQQQSDLALDLLNNDVLFEHRFGKDHYMKFLRDLFMTRHRISKGDESDSFFSPLIEHVRKKECPDKAIDLLKGAYKRFNEDAFFAQHLARLNYKHERFEAAEQWAKTAVAKMPHNSYILDTKGQVYRQWFLAKCKAIKQNETPENTVDPLEMAFKAIECFQACENAAVQDNDTMNNAGFVGVVEVGCALLKLMSNLQVFSRRRRPSELSRYLLTNYIPPEIETPWENFHYKLKNLQKTMLEALEWISEDLSFFQTDLNTDEEKTAETVESTIKHPIHWLVNKSHDYGRYFSGASPGTDKNREKLSPVMKRMMIHYHGGGNITTILFLLTNQKDRDPVPVLEKIISFYPSDPMRAQLPQVDLVNYIASHLALSLLSPESPKLAAFQDLQRMSYQFLKEGQKKSISNANFLLVLLFWPEEQETEVEKERKYKIVLSAVENLQRDYEKRLKDIPPRKKRIYTHFFLSNGTGFEKFVHKSKFETITKLFSVPEKRLKWFSGEVWKMPEMSKLLKCVTGWTEDEKVYLEGPKGMKFHIPALKMSSIPHKNENVTFYLGFTLKGPVAYNITVQTQN", "length": 1526, "header": "tr|F1Q795-1|F1Q795_DANRE Isoform 1 of Sterile alpha motif domain-containing protein 9-like OS=Danio rerio OX=7955 GN=samd9l PE=4 SV=2 CANONICAL=F1Q795-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101882987", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882987", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JVT8-1", "protein_name": "Sterile alpha motif domain-containing protein 9-like", "gene_name": "Samd9l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDRHVTQPKLIKDWTKEHVRKWITEDLKIDEKYAQIVFEEEVTGMVLQELTEKDLREMGLPRGPALLIKRMYNKLISSPEGHNQDSRQLNNKTLSINEQPKKSNSEEENSISSNSDFGLRETGQNEEQEPSIMKVNTLGDVETKDMKDNMPKSEQMSCMPHPFNFAHDAKRYIEHSILRVAETGPLNLIDPVHEFKAFTNTETATQEQMKMKFSNETFRFAAACMNTRTNGTIHFGVKDKPHGEIVGVQVTSKDIFINHFNVMITKYFEDSDIHEARACIREPRFVEVLLLNNTQSNRFVIEVDVIPKHSICQEKYFYVMLQTCTGTTWKQSKDTSLFVREGASSRDILGNPKQRDREFKKFLENLKMSIASRKAAEECMVVSKKDSEGLKLSKLLTRHQGSLDKSYYDWYILVTNSCVPTQMEHLDFIKEIKLFAVLDFDPYSHIKGVVKAYRESRVANLHLPSHYEEKTTIEEKISTLKLYEQPSWIFCNGRVDLSCQPLEPHLWQRDRASGVRKLISFLTDGNIIARGKVLVVFLLLSPVENQKDPLLETFCAFYQVFNGMDNMLCICVNPSIYQQWSDLLQVRLEIKDDLAKHSISTLNIELVNSTILKLKSVIQSSRRFLPSCGSSSVILEKMDEDIMSALEILCENECRDTDIEKDESQFLEFKKLREEHFYRGGRVSWWNFYFSSENYSSAFVKRDNFEELTTLIQQCADSPKPVFAKVINLYHHPGCGGTTLAMHVLWDLKQKFRCAVLKNKATDFIEIGEQVSKLISYKASSHQDYIPVLLLVDDFEEQQNTYILQNAINSFIAEKGVRYEKTLVIILNCMRSQNPDESAKLADSISLKYQLSPKEKRAFEAKLQEIEKEYKDCENFYSFMILKDNFDTTYIKNVVKNTLKDLDAHSRKAQFISYLALLNTYVIDSTISVSQCEIFLGITYTIKRGKPETVEDNMGTYSTLLIRTEVSDYGRYAGIRIIHPLIAIHCLKELEMSHGMDKCQIALNMLEENIFYDSGIGRDKFKHDVQTLLLTRQRKEHGAEIDTLFSPFIEELQNEQTEKVLTAGSDRFPQNAFICQALARHFYLKEKNFSTALVWANQAKRKAPKNSYISDTLGQVYKSEIRQWLSKNSTCRSISVDDLTRFLEVAEKASKAFKESQEQTDSKDYEIEVWSPQKSQRRYDTYNTAGFFGEIEVGLDTIQLLQLTPLFHKENEMSKESMAQFLSGKGTIPPDPKGEYYVVLNKFKSFLQNLQSDLKRCFDFFLDYMGLLKPRNTPKELTELSLSKKVSRCFKKYADLFCQELQGKEDLLLQEENCRKRIKAWRADTFSGLLEYLNPNHKEANNMENIVEHYTFLLQHTLNKQLSKALIKDTQNFILANIILSCLKPSSKHILPFSTLKKKLREVLQIVGLTHSYPDPYFLACLLFWPENKELDQDSSLIEKYVSSLNRSFRRQYKHMCRSRQPSTLFYLGQKKGLNSLVHKAEIERYFSEVQDSNSFWQSGVVWEKGEVKDILCLLDGQAEGKLISLEYGTEANIKIPMTSVHSGPLRSGRNMERVSFYLGFSIEGPLAYGIKVI", "length": 1574 }, "evidence": [ { "id": "MGI:1343184", "url": "https://alliancegenome.org/gene/MGI:1343184#orthology", "database": "AGR" }, { "id": "HGNC:1349", "url": "https://alliancegenome.org/gene/HGNC:1349#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q69Z37-1", "protein_name": "Sterile alpha motif domain-containing protein 9-like", "gene_name": "Samd9l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSGQVTQPKLIKDWTKEHVRKWVTEDLNIVEKYAQILFKEEVTGMVLQELTEEDLREMGLPRGPALLIKRMYNKLISSPESHNQDSRELNDKKLSTKEQQTKTKNEEENSVSSNSDHGLRETGQNEEQEPSLTKENMLGDVVTKDMEDNKPKPEQMSCTPYPFDSFCDVKQYIEHSILRVAETGPLNLIDPIHEFKAFTNTKKATEEDIKMKFSNETFRFAAACMNSRTNGTIHFGVKDKPHGEIVGVQVTSKDIFVNHFNTMITKYFEDSEISEARACIREPRFVEVLLQNNTQSNRFVIEVDVIPRHSICQEKYFYIMMQSSTGKTWKQSKDTSLFVREGASSKNILGNPNQRDREFKKFLEDLKMWTASRKAAEEELRMVTKKESEGLKLSKLLTRHQGSLDESYYDWYILVTNTCAPTQLEHLEFIKEMKLFAVLDFDPYSHIKGVVKAYRESRIANLHLPSHYEEKTTIAEKISTLKLYEQPSWIFCNGRVDLSCQPLEPHLWQRDRASGVRRLISFLTDENIIVKGKVLVVFLLLSPIENQKDPLIETFCAFYQVFNGMDNMLCICVNSAIYQQWSDLLQVRLEIKDDLAKHSISTLNIELVNNTILKLKSVIQSSRRFLPSCGSSSVILEKMDEDIMSALEILCENECKDTDIEKDESQFLEFKKSREEHFYRGGRVSWWNFYFSSENYSSAFVKRDSFEELTTLIQQCADSPKPVFVKVINLYHHPGCGGTTLAMHVLWDLKQKFRCAVLKNKATDFVEIGEQVSKLMSYKATSHEDFIPVLLLVDDFEEQENAYILQNAINAFIAEKGLRYEKTLVIILNCMRSQNPDESAKLANSISLKYQLSPKEQRAFEAKLQEIEKEHKNCENFYSFMILKGNFDTTYIKNVVKNTLKDLDAKSRRAQLISYLALLNSYVTDSTISVSQCEIFLGITYTKKYGKPETVEKNMGTYSTLLIRTEVSDYGRYTGIRIIHPLIATHCLKELEMSYRMDKCQIALNMLEENVLYDSGLGRDKFKYDVQTLLLTRQRKEHGAETDTLFSPLIEELQNEETEKVLIAGSDRFPQNAFICQALARHFYIKEKNFSTALVWANLAKRKAPKNSYISDTLGQVYKSELNSGWEVAEKASKAFKESQNQSDSKDYGTEAWSPQNSQRRYDTFNTAGFFGEIEVGLDTIQLLQLTPLFHKENEISKESMAEFLSGKGTILSDPKGEYCVVLSKFTSLLQNLHSDLERCFHFFGDYMGFLKPRNTPKELTELLLSKKVSRCFKKYVELFCHLDTNLVQGKEDLLLQKENCRKRIQAWRADTFSGLLEYLNPNHKEANNIENIVGNYTFLLQDILNKQLSKVLTKDIQNFILANIILSCLKPSSKYILPFSTLKKKLREVLQIVGLTHSYPDPYFLACLLFWPENKELDEDSTLIEKYVSSLNRSFRRQYKHMCRSRQPSTLFYLGQKKGLNSLVHKAEIERYFSEVQDSNSFWHSGVVWEKREVKDLLRLLDGQAEGKLISLEYGTEAKIKIPVTSVYSAPLRSGRNIERVSFYLGFSIEGPLAYGIKVI", "length": 1561 }, "evidence": [ { "id": "MGI:1343184", "url": "https://alliancegenome.org/gene/MGI:1343184#orthology", "database": "AGR" }, { "id": "HGNC:1349", "url": "https://alliancegenome.org/gene/HGNC:1349#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-738", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-738#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IVG5-1", "protein_name": "Sterile alpha motif domain-containing protein 9-like", "gene_name": "SAMD9L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSKQVSLPEMIKDWTKEHVKKWVNEDLKINEQYGQILLSEEVTGLVLQELTEKDLVEMGLPWGPALLIKRSYNKLNSKSPESDNHDPGQLDNSKPSKTEHQKNPKHTKKEEENSMSSNIDYDPREIRDIKQEESILMKENVLDEVANAKHKKKGKLKPEQLTCMPYPFDQFHDSHRYIEHYTLQPETGALNLIDPIHEFKALTNTETATEVDIKMKFSNEVFRFASACMNSRTNGTIHFGVKDKPHGEIVGVKITSKAAFIDHFNVMIKKYFEESEINEAKKCIREPRFVEVLLQNNTPSDRFVIEVDTIPKHSICNDKYFYIQMQICKDKIWKQNQNLSLFVREGASSRDILANSKQRDVDFKAFLQNLKSLVASRKEAEEEYGMKAMKKESEGLKLVKLLIGNRDSLDNSYYDWYILVTNKCHPNQIKHLDFLKEIKWFAVLEFDPESMINGVVKAYKESRVANLHFPNQYEDKTTNMWEKISTLNLYQQPSWIFCNGRSDLKSETYKPLEPHLWQRERASEVRKLILFLTDENIMTRGKFLVVFLLLSSVESPGDPLIETFWAFYQALKGMENMLCISVNSHIYQRWKDLLQTRMKMEDELTNHSISTLNIELVNSTILKLKSVTRSSRRFLPARGSSSVILEKKKEDVLTALEILCENECTETDIEKDKSKFLEFKKSKEEHFYRGGKVSWWNFYFSSENYSSDFVKRDSYEKLKDLIHCWAESPKPIFAKIINLYHHPGCGGTTLAMHVLWDLKKNFRCAVLKNKTTDFAEIAEQVINLVTYRAKSHQDYIPVLLLVDDFEEQENVYFLQNAIHSVLAEKDLRYEKTLVIILNCMRSRNPDESAKLADSIALNYQLSSKEQRAFGAKLKEIEKQHKNCENFYSFMIMKSNFDETYIENVVRNILKGQDVDSKEAQLISFLALLSSYVTDSTISVSQCEIFLGIIYTSTPWEPESLEDKMGTYSTLLIKTEVAEYGRYTGVRIIHPLIALYCLKELERSYHLDKCQIALNILEENLFYDSGIGRDKFQHDVQTLLLTRQRKVYGDETDTLFSPLMEALQNKDIEKVLSAGSRRFPQNAFICQALARHFYIKEKDFNTALDWARQAKMKAPKNSYISDTLGQVYKSEIKWWLDGNKNCRSITVNDLTHLLEAAEKASRAFKESQRQTDSKNYETENWSPQKSQRRYDMYNTACFLGEIEVGLYTIQILQLTPFFHKENELSKKHMVQFLSGKWTIPPDPRNECYLALSKFTSHLKNLQSDLKRCFDFFIDYMVLLKMRYTQKEIAEIMLSKKVSRCFRKYTELFCHLDPCLLQSKESQLLQEENCRKKLEALRADRFAGLLEYLNPNYKDATTMESIVNEYAFLLQQNSKKPMTNEKQNSILANIILSCLKPNSKLIQPLTTLKKQLREVLQFVGLSHQYPGPYFLACLLFWPENQELDQDSKLIEKYVSSLNRSFRGQYKRMCRSKQASTLFYLGKRKGLNSIVHKAKIEQYFDKAQNTNSLWHSGDVWKKNEVKDLLRRLTGQAEGKLISVEYGTEEKIKIPVISVYSGPLRSGRNIERVSFYLGFSIEGPLAYDIEVI", "length": 1584 }, "evidence": [ { "id": "MGI:1343184", "url": "https://alliancegenome.org/gene/MGI:1343184#orthology", "database": "AGR" }, { "id": "HGNC:1349", "url": "https://alliancegenome.org/gene/HGNC:1349#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-738", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-738#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "F1Q795", "url": "https://www.uniprot.org/uniprotkb/F1Q795" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1096, "end_pos": 1098, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1127, "end_pos": 1129, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1237, "end_pos": 1239, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1276, "end_pos": 1278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1421, "end_pos": 1423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1503, "end_pos": 1505, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1519, "end_pos": 1521, "annotation": "n_glycosylation_sequon" }, { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 293, "end_pos": 295, "annotation": "n_glycosylation_sequon" }, { "start_pos": 409, "end_pos": 411, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 676, "end_pos": 678, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1Q795", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q795" }, { "id": "PS50105", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50105" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SAM", "eco_id": "ECO_0000259", "start_pos": 12, "end_pos": 58, "start_aa": "Trp", "end_aa": "Met", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1096, "end_pos": 1098 }, { "start_pos": 1127, "end_pos": 1129 }, { "start_pos": 1237, "end_pos": 1239 }, { "start_pos": 1276, "end_pos": 1278 }, { "start_pos": 1421, "end_pos": 1423 }, { "start_pos": 1503, "end_pos": 1505 }, { "start_pos": 1519, "end_pos": 1521 }, { "start_pos": 196, "end_pos": 198 }, { "start_pos": 293, "end_pos": 295 }, { "start_pos": 409, "end_pos": 411 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 676, "end_pos": 678 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B8JJT0-1", "uniprot_ac": "B8JJT0", "uniprot_id": "B8JJT0_DANRE", "mass": { "chemical_mass": 68727.0, "monoisotopic_mass": 68727.0 }, "refseq": { "ac": "NP_001005316", "name": "kelch-like protein 6", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005316" }, "gene_names": [ { "name": "klhl6", "type": "recommended", "evidence": [ { "id": "B8JJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ] }, { "name": "klhl6", "type": "synonym", "evidence": [ { "id": "NP_001005316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005316" } ] }, { "name": "si:dz198m22.2", "type": "synonym", "evidence": [ { "id": "NP_001005316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005316" }, { "id": "B8JJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ] }, { "name": "zgc:152803", "type": "synonym", "evidence": [ { "id": "NP_001005316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005316" }, { "id": "B8JJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ] } ], "protein_names": [ { "name": "Kelch-like protein 6", "type": "synonym", "evidence": [ { "id": "B8JJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JJT0/entry#names_and_taxonomy" } ] }, { "name": "kelch-like 6", "type": "synonym", "evidence": [ { "id": "NP_001005316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005316" } ] }, { "name": "kelch-like protein 6", "type": "synonym", "evidence": [ { "id": "NP_001005316", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005316" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01014096.1, SRR32588724.1916751.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN08196787 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On or before Jun 14, 2012 this sequence version replaced NP_001071218.1, NP_001005316.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001005316", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005316" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JJT0", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "klhl6", "url": "https://www.uniprot.org/uniprotkb/B8JJT0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030616-325", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-325", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000026990", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000026990", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd18236", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18236", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd18446", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18446", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "368818", "url": "https://www.ncbi.nlm.nih.gov/gene/368818", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029851", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029851", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:368818", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:368818", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WYFVEMV", "url": "https://omabrowser.org/oma/group/WYFVEMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JJT0", "url": "https://www.orthodb.org/?gene=B8JJT0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF428", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF428", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001005316", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001005316", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TVI1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TVI1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TVI1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TVI1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JJT0", "url": "https://www.uniprot.org/uniprotkb/B8JJT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JJT0-1", "url": "https://www.uniprot.org/uniprotkb/B8JJT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030616-325", "url": "https://zfin.org/ZDB-GENE-030616-325", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MADAPQNDSECPSSGQTEASAGGLSLLESSTQENQEDGQVLFEDSVFAGCLQDGLHSLCLEDSLTDVILNVQSQSFKCHRVVLAAASHYFRAMFCNDLREKHEENVNIKGIDADTMRILLDYTYTSKVTITKDNVQRMLEAACLFQFPRIVDACASYLAEALHPENCVGILHLADVHSLESLKTQVHSYIVQNFSQVVDHEEILELPADVLVSLIQHDDLGVTEEEQVFDTVIRWVKAREDDRTALLPRVLTHVRLPLLDPWFFVERVEGDPLIRHCAEVFPLLQEARVYHLSGKEVISERTKPRVQEFQSEVFMIIGGCTKEEKFVSEVTCLDPLRRSRLEVAKLPNTEMETESENKKWVEFACVTFRNEVYISGGKETLHDVWKYNASLNKWIQIEFLNTGRWRHKMAVAGGKVYVLGGFDGTQRLNCVEAYDPFHNCWSEAAPLMLSVSSFSAASFDRCIYVIGGGPNGKLATNNMQCFDSQSNKWSLKCPMPTEAKCTNAVTFKDAIFVVGGAMKALYSYSPLVDSWTLIIQLGCERASCGIAACNNKLFITGGRDDKNEVIATVLCWNPDTKKLTEECVLPRGVSHHGSVTIRKSYTHIRRITPGTATG", "length": 614, "header": "tr|B8JJT0-1|B8JJT0_DANRE Isoform 1 of Kelch-like protein 6 OS=Danio rerio OX=7955 GN=klhl6 PE=4 SV=1 CANONICAL=B8JJT0-1" }, "isoforms": [ { "isoform_ac": "A0AB32TVI1-1", "url": "https://www.uniprot.org/uniprotkb/B8JJT0/entry#A0AB32TVI1-1", "sequence": { "sequence": "MTLNVPHLARPKLQLEDGLHSLCLEDSLTDVILNVQSQSFKCHRVVLAAASHYFRAMFCNDLREKHEENVNIKGIDADTMRILLDYTYTSKVTITKDNVQRMLEAACLFQFPRIVDACASYLAEALHPENCVGILHLADVHSLESLKTQVHSYIVQNFSQVVDHEEILELPADVLVSLIQHDDLGVTEEEQVFDTVIRWVKAREDDRTALLPRVLTHVRLPLLDPWFFVERVEGDPLIRHCAEVFPLLQEARVYHLSGKEVISERTKPRVQEFQSEVFMIIGGCTKEEKFVSEVTCLDPLRRSRLEVAKLPNTEMETESENKKWVEFACVTFRNEVYISGGKETLHDVWKYNASLNKWIQIEFLNTGRWRHKMAVAGGKVYVLGGFDGTQRLNCVEAYDPFHNCWSEAAPLMLSVSSFSAASFDRCIYVIGGGPNGKLATNNMQCFDSQSNKWSLKCPMPTEAKCTNAVTFKDAIFVVGGAMKALYSYSPLVDSWTLIIQLGCERASCGIAACNNKLFITGGRDDKNEVIATVLCWNPDTKKLTEECVLPRGVSHHGSVTIRKSYTHIRRITPGTATG", "length": 578, "header": "tr|A0AB32TVI1-1|B8JJT0_DANRE Computationally mapped isoform of Kelch-like protein 6 OS=Danio rerio OX=7955 GN=klhl6 PE=4 SV=1 CANONICAL=B8JJT0-1" }, "locus": {} }, { "isoform_ac": "B8JJT0-1", "url": "https://www.uniprot.org/uniprotkb/B8JJT0/entry#B8JJT0-1", "sequence": { "sequence": "MADAPQNDSECPSSGQTEASAGGLSLLESSTQENQEDGQVLFEDSVFAGCLQDGLHSLCLEDSLTDVILNVQSQSFKCHRVVLAAASHYFRAMFCNDLREKHEENVNIKGIDADTMRILLDYTYTSKVTITKDNVQRMLEAACLFQFPRIVDACASYLAEALHPENCVGILHLADVHSLESLKTQVHSYIVQNFSQVVDHEEILELPADVLVSLIQHDDLGVTEEEQVFDTVIRWVKAREDDRTALLPRVLTHVRLPLLDPWFFVERVEGDPLIRHCAEVFPLLQEARVYHLSGKEVISERTKPRVQEFQSEVFMIIGGCTKEEKFVSEVTCLDPLRRSRLEVAKLPNTEMETESENKKWVEFACVTFRNEVYISGGKETLHDVWKYNASLNKWIQIEFLNTGRWRHKMAVAGGKVYVLGGFDGTQRLNCVEAYDPFHNCWSEAAPLMLSVSSFSAASFDRCIYVIGGGPNGKLATNNMQCFDSQSNKWSLKCPMPTEAKCTNAVTFKDAIFVVGGAMKALYSYSPLVDSWTLIIQLGCERASCGIAACNNKLFITGGRDDKNEVIATVLCWNPDTKKLTEECVLPRGVSHHGSVTIRKSYTHIRRITPGTATG", "length": 614, "header": "tr|B8JJT0-1|B8JJT0_DANRE Isoform 1 of Kelch-like protein 6 OS=Danio rerio OX=7955 GN=klhl6 PE=4 SV=1 CANONICAL=B8JJT0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 608, "start_aa": "Thr", "end_pos": 608, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr608", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Saltatory evolution of the ectodermal neural cortex gene family at the vertebrate origin.", "journal": "Genome Biol. Evol.", "date": "2013", "authors": "Feiner Nathalie, Murakami Yasunori, Breithut Lisa, Mazan Sylvie, Meyer Axel, Kuraku Shigehiro", "evidence": [ { "database": "UniProtKB", "id": "B8JJT0", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ], "reference": [ { "type": "PubMed", "id": "23843192", "url": "https://glygen.org/publication/PubMed/23843192" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JJT0", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8JJT0", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Sequential, Divergent, and Cooperative Requirements of Foxl2a and Foxl2b in Ovary Development and Maintenance of Zebrafish.", "journal": "Genetics", "date": "2017", "authors": "Yang Yan-Jing, Wang Yang, Li Zhi, Zhou Li, Gui Jian-Fang", "evidence": [ { "database": "UniProtKB", "id": "B8JJT0", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ], "reference": [ { "type": "PubMed", "id": "28193729", "url": "https://glygen.org/publication/PubMed/28193729" } ] } ], "pathway": [ { "id": "dre:368818", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:368818", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A1Z1-1", "protein_name": "Kelch-like family member 6", "gene_name": "Klhl6", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAGQRGACTMSDVVERSLEGPLALTTDKSSQKRGDFVEILTGEKVKFDDTRLSLILQNGLETLREENALTDVILCVDIQEFSCHRVVLAAASNYFRAMFCNDLKEKYEKRIIIKGVDAETMHTLLNYTYTSKALITKQNVQRVLEAANLFQFLQLVDACASFLTEALNPENCIGILRLADTHSLDSLKTQVQSYIIQNFVQILNSEEFLELPVDTLYHILRSDDLCVTEESQVFETVMSWVRHKQSERLCLLPCVLENVRLPLLDPWYFVEMVEADPLIRQCPEVFPLLQEARMYHLSGNEIISERTKPRMHEFQSEVFMIIGGCTKDERFVAEVTCLDPLRRSRLEVAKLPLTEHELESGKETQHDVWKYNSSINKWIQIEYLNIGRWRHKMVVLGGKVYVIGGFDGLQRINNVETYDPFHNCWSEAAPLLVHVSSFAATSHKKKLYVIGGGPNGKLATDKTQCYDPSTNKWVLKSAMPVEAKCINAVSFQDHIYVVGGAMRALYAYSPLEDSWCLVTQLSHERASCGIAPCNNKLYITGGRDEKNEVIATVLCWDPEAQKLTEECVLPRGVSHHGSVTIRKSYTHIRRVVPGAVSV", "length": 598 }, "evidence": [ { "id": "HGNC:18653", "url": "https://alliancegenome.org/gene/HGNC:18653#orthology", "database": "AGR" }, { "id": "B8JJT0", "url": "https://omabrowser.org/oma/group/B8JJT0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1P3D7-1", "protein_name": "Kelch like family member 6", "gene_name": "KLHL6", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGDTLEKSCEDAEFSLDNECSTKMGELVEVSSGEKIKFDDTGLSLVLQNGLENLRLENSLTDVILCVDSREFSCHRVVLAAASNYFRAMFCNDLREKYEEKIILKGVDAETMNILLDYTYTSKMLITKQNVQKVLEAASLFQFLRMVDACASFLTESLQPDNCVGILRLADAHSLHSLKQQVQNYIIQNFTQVLSYEEFLELPADVLCSTLKSDDLYVTEEAQVFETVMNWVRYKESERFPLLPSVLENVRLPLLDPWYFVETVEADQLIRQCPDVFPLLQEARMYHLSGNEIITERTKPRMHEFQSEVFMIIGGCTKDEKFVAEVTCLDPLRRSRLEVAKLPITEQETENENKKWVEFACITLKNEVYISGGKETQHDVWKYNASINKWIQIEYLNIGRWRHKMAVLGGKVYVIGGFDGVQRINSMEAYDPFHNCWSEAAPLMINVSSFAAASYKKKLYVIGGGPNGKLATDKTQCYDPAANTWSLRAPMPVEAKCINAASFRDHIYVVGGAMKALYSYSPQEDTWCLVTQFTHERASCGISPCNNKLFITGGRDEKNEVIATVLCWDPETQKLTEECVLPRGVSHHGSVTLRKSYTHIRRIVPGAVSV", "length": 610 }, "evidence": [ { "id": "B8JJT0", "url": "https://omabrowser.org/oma/group/B8JJT0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q6V595-1", "protein_name": "Kelch-like protein 6", "gene_name": "Klhl6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAGQRGACTMSDVVERSLEGPLALTTDKSSQKRGDLVEILTGEKVKFDDTRLSLILQNGLETLREENALTDVILCVDVQEFSCHRVVLAAASNYFRAMFCNDLKEKYEKRIIIKGVDAETMHTLLVYTYTSKALITKQNVQRVLEAANLFQFLQLVDACASFLTEALNPENCIGILRLADTHSLDSLKMQVQSYIIQNFVQILNSEEFLELPVDTLYHILRSDDLCVTEEAQVFETVMSWVRHKQSERLCLLPCVLENVRLPLLDPWYFVEMVEADPLIRQCPEVFPLLQEARMYHLSGNEIISERTKPRMHEFQSEVFMIIGGCTKDERFVAEVTCLDPLRRSRLEVAKLPLTEHELESENKKWVEFACVTLKNEVYISGGKETQHDVWKYNSSINKWIQIEYLNIGRWRHKMVVLGGKVYVLGGFDGLQRINNVETYDPFHNCWSEAAPLHVHVSSFAATSHKKKLYVIGGGPNGKLATDKTQCYDPSTNKWVLKSAMPVEAKCINAVSFQDHIYVVGGAMRALYAYSPLEDSWCLVTQLSHERASCGIAPCNNKLYITGGRDEKNEVIATVLCWDPEAQKLTEECVLPRGVSHHGSVTIRKSYTHIRRVVPGAVSV", "length": 619 }, "evidence": [ { "id": "HGNC:18653", "url": "https://alliancegenome.org/gene/HGNC:18653#orthology", "database": "AGR" }, { "id": "B8JJT0", "url": "https://omabrowser.org/oma/group/B8JJT0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WZ60-1", "protein_name": "Kelch-like protein 6", "gene_name": "KLHL6", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLMAGQRGAWTMGDVVEKSLEGPLAPSTDEPSQKTGDLVEILNGEKVKFDDAGLSLILQNGLETLRMENALTDVILCVDIQEFSCHRVVLAAASNYFRAMFCNDLKEKYEKRIIIKGVDAETMHTLLDYTYTSKALITKQNVQRVLEAANLFQFLRMVDACASFLTEALNPENCVGILRLADTHSLDSLKKQVQSYIIQNFVQILNSEEFLDLPVDTLHHILKSDDLYVTEEAQVFETVMSWVRHKPSERLCLLPYVLENVRLPLLDPWYFVETVEADPLIRQCPEVFPLLQEARMYHLSGNEIISERTKPRMHEFQSEVFMIIGGCTKDERFVAEVTCLDPLRRSRLEVAKLPLTEHELESENKKWVEFACVTLKNEVYISGGKETQHDVWKYNSSINKWIQIEYLNIGRWRHKMVVLGGKVYVIGGFDGLQRINNVETYDPFHNCWSEAAPLLVHVSSFAATSHKKKLYVIGGGPNGKLATDKTQCYDPSTNKWSLKAAMPVEAKCINAVSFRDRIYVVGGAMRALYAYSPLEDSWCLVTQLSHERASCGIAPCNNRLYITGGRDEKNEVIATVLCWDPEAQKLTEECVLPRGVSHHGSVTIRKSYTHIRRIVPGAVSV", "length": 621 }, "evidence": [ { "id": "HGNC:18653", "url": "https://alliancegenome.org/gene/HGNC:18653#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030616-325", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030616-325#orthology", "database": "AGR" }, { "id": "B8JJT0", "url": "https://omabrowser.org/oma/group/B8JJT0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B8JJT0", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "B8JJT0", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "B8JJT0", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ], "pmid": "" }, { "name": "B cell receptor signaling pathway", "id": "GO:0050853", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0050853", "evidence": [ { "database": "UniProtKB", "id": "B8JJT0", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "B8JJT0", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 193, "end_pos": 195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 388, "end_pos": 390, "annotation": "n_glycosylation_sequon" }, { "start_pos": 7, "end_pos": 9, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8JJT0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JJT0" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 65, "end_pos": 132, "start_aa": "Thr", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 608 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 193, "end_pos": 195 }, { "start_pos": 388, "end_pos": 390 }, { "start_pos": 7, "end_pos": 9 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1Q5B0-1", "uniprot_ac": "F1Q5B0", "uniprot_id": "F1Q5B0_DANRE", "mass": { "chemical_mass": 45749.0, "monoisotopic_mass": 45749.0 }, "refseq": { "ac": "NP_001349485", "name": "SH2 domain-containing protein 5 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001349485" }, "gene_names": [ { "name": "sh2d5", "type": "recommended", "evidence": [ { "id": "F1Q5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0" } ] }, { "name": "fa11f09", "type": "synonym", "evidence": [ { "id": "NP_001349485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001349485" }, { "id": "F1Q5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0" } ] }, { "name": "sh2d5", "type": "synonym", "evidence": [ { "id": "NP_001349485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001349485" } ] }, { "name": "wu:fa11f09", "type": "synonym", "evidence": [ { "id": "NP_001349485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001349485" }, { "id": "F1Q5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0" } ] }, { "name": "zgc:113447", "type": "synonym", "evidence": [ { "id": "NP_001349485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001349485" }, { "id": "F1Q5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0" } ] } ], "protein_names": [ { "name": "SH2 domain-containing protein 5 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001349485", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001349485" }, { "id": "F1Q5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.50269434.1, SRR32588716.11014827.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898400, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000011.1. On Apr 20, 2018 this sequence version replaced XP_005169461.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001349485", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001349485" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1Q5B0", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sh2d5", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050327-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-67", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00173", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00173", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd13157", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13157", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "541529", "url": "https://www.ncbi.nlm.nih.gov/gene/541529", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006020", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006020", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:541529", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:541529", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "F1Q5B0", "url": "https://www.orthodb.org/?gene=F1Q5B0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15832", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15832", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15832:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15832:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00640", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00640", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001349485", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001349485", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB13A3I4", "url": "https://www.uniprot.org/uniprotkb/A0AB13A3I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13A3I4-1", "url": "https://www.uniprot.org/uniprotkb/A0AB13A3I4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q5B0", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1Q5B0-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050327-67", "url": "https://zfin.org/ZDB-GENE-050327-67", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFKRQTPQPGSVWNMGETAGREHGTVTRSAEYIGSFPVDDSCLDDQIQQLHTQLKSLKNCKSKRTVSLRFSVKGVKVYDEDETTLLMAHAMCRVSLSTARPSDAQFAFASHNPGNSDAQLYCHLFRARHARAAQFLNLLLCRCFQLYFLEKHPEEAQEECSGKKPSRAPSLLNQGFPLSVSALVSFRRAPTQGLLPGAKLFSQQSTEQVSSPEEGPTSSPTIVRKMAIRTKELRSGAYRSFTFTPLKQRHLQDKLSAPQEKEQATAKACMSRAPSLAETEEALAQAVWCWAGVSSDCSSSLLADDVLGAFLLCPHPKKPNRGSLIVRFSSGLVTYAIKNSKGKFRLEKCHTDFESLAALMEHYTEFGDELECSLSCARVNHCYDWEEMVNKGSRLLQDNKKGTFKCRSWV", "length": 410, "header": "tr|F1Q5B0-1|F1Q5B0_DANRE Isoform 1 of SH2 domain-containing protein 5 isoform 1 OS=Danio rerio OX=7955 GN=sh2d5 PE=4 SV=1 CANONICAL=F1Q5B0-1" }, "isoforms": [ { "isoform_ac": "A0AB13A3I4-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0/entry#A0AB13A3I4-1", "sequence": { "sequence": "MGETAGREHGTVTRSAEYIGSFPVDDSCLDDQIQQLHTQLKSLKNCKSKRTVSLRFSVKGVKVYDEDETTLLMAHAMCRVSLSTARPSDAQFAFASHNPGNSDAQLYCHLFRARHARAAQFLNLLLCRCFQLYFLEKHPEEAQEECSGKKPSRAPSLLNQGFPLSVSALVSFRRAPTQGLLPGAKLFSQQSTEQVSSPEEGPTSSPTIVRKMAIRTKELRSGAYRSFTFTPLKQRHLQDKLSAPQEKEQATAKACMSRAPSLAETEEALAQAVWCWAGVSSDCSSSLLADDVLGAFLLCPHPKKPNRGSLIVRFSSGLVTYAIKNSKGKFRLEKCHTDFESLAALMEHYTEFGDELECSLSCARVNHCYDWEEMVNKGSRLLQDNKKGTFKCRSWV", "length": 396, "header": "tr|A0AB13A3I4-1|F1Q5B0_DANRE Computationally mapped isoform of SH2 domain-containing protein 5 isoform 1 OS=Danio rerio OX=7955 GN=sh2d5 PE=4 SV=1 CANONICAL=F1Q5B0-1" }, "locus": {} }, { "isoform_ac": "F1Q5B0-1", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0/entry#F1Q5B0-1", "sequence": { "sequence": "MFKRQTPQPGSVWNMGETAGREHGTVTRSAEYIGSFPVDDSCLDDQIQQLHTQLKSLKNCKSKRTVSLRFSVKGVKVYDEDETTLLMAHAMCRVSLSTARPSDAQFAFASHNPGNSDAQLYCHLFRARHARAAQFLNLLLCRCFQLYFLEKHPEEAQEECSGKKPSRAPSLLNQGFPLSVSALVSFRRAPTQGLLPGAKLFSQQSTEQVSSPEEGPTSSPTIVRKMAIRTKELRSGAYRSFTFTPLKQRHLQDKLSAPQEKEQATAKACMSRAPSLAETEEALAQAVWCWAGVSSDCSSSLLADDVLGAFLLCPHPKKPNRGSLIVRFSSGLVTYAIKNSKGKFRLEKCHTDFESLAALMEHYTEFGDELECSLSCARVNHCYDWEEMVNKGSRLLQDNKKGTFKCRSWV", "length": 410, "header": "tr|F1Q5B0-1|F1Q5B0_DANRE Isoform 1 of SH2 domain-containing protein 5 isoform 1 OS=Danio rerio OX=7955 GN=sh2d5 PE=4 SV=1 CANONICAL=F1Q5B0-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 217, "start_aa": "Thr", "end_pos": 217, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr217", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "A0AB13A3I4", "url": "https://www.uniprot.org/uniprotkb/A0AB13A3I4" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Female Sex Development and Reproductive Duct Formation Depend on Wnt4a in Zebrafish.", "journal": "Genetics", "date": "2019", "authors": "Kossack Michelle E, High Samantha K, Hopton Rachel E, Yan Yi-Lin, Postlethwait John H, Draper Bruce W", "evidence": [ { "database": "UniProtKB", "id": "A0AB13A3I4", "url": "https://www.uniprot.org/uniprotkb/A0AB13A3I4" } ], "reference": [ { "type": "PubMed", "id": "30446521", "url": "https://glygen.org/publication/PubMed/30446521" } ] }, { "title": "Functional Characterization and Expression Analyses Show Differential Roles of Maternal and Zygotic Dgcr8 in Early Embryonic Development.", "journal": "Front. Genet.", "date": "2020", "authors": "Zhu Zeyao, Liu Yun, Xu Wen, Liu Taian, Xie Yuxin, Sham Kathy W Y, Sha Ou, Cheng Christopher H K", "evidence": [ { "database": "UniProtKB", "id": "A0AB13A3I4", "url": "https://www.uniprot.org/uniprotkb/A0AB13A3I4" } ], "reference": [ { "type": "PubMed", "id": "32296464", "url": "https://glygen.org/publication/PubMed/32296464" } ] }, { "title": "Spatio-temporal mRNA tracking in the early zebrafish embryo.", "journal": "Nat. Commun.", "date": "2021", "authors": "Holler Karoline, Neuschulz Anika, Drewe-Bo\u00df Philipp, Mintcheva Janita, Spanjaard Bastiaan, Arsi\u00e8 Roberto, Ohler Uwe, Landthaler Markus, Junker Jan Philipp", "evidence": [ { "database": "UniProtKB", "id": "A0AB13A3I4", "url": "https://www.uniprot.org/uniprotkb/A0AB13A3I4" } ], "reference": [ { "type": "PubMed", "id": "34099733", "url": "https://glygen.org/publication/PubMed/34099733" } ] } ], "pathway": [ { "id": "dre:541529", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:541529", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A096MJ64-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "Sh2d5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQRAGAGARRASDCGPAPYRPRCIAKFAQYVGSFPVDDLDTQESVCLVQQHLWALQDCSRRRAVILKFSLQGLKIYSGEGEVLLMAHALKRILYATWNPAACQFAFVARNPRSPASKLFCHLFVGSQPGEINILYLLLCRSFQLAYLLQHPEERAQPEPSLVPGGDMSLKPLCSPGVAPALVREPFSRDQLSQNVHALVSFRRLPAEGLLGSNGKELPEPEGRGGTRHIRLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAAWEAWPRGPGSPSCLVENEGSLTENIWAFAGLSRSCALALLRRDVHGAFLLWPEPGTSGQWSLSVRTQCGVVSHQVFRNHLGRYCLEHLPAEFPSLEALVESHAGMERSLFCPLSMGRLNPTYEEQDSGPEGRFPRTLRPLSHAKSEAELQGLG", "length": 429 }, "evidence": [ { "id": "HGNC:28819", "url": "https://alliancegenome.org/gene/HGNC:28819#orthology", "database": "AGR" }, { "id": "MGI:2446215", "url": "https://alliancegenome.org/gene/MGI:2446215#orthology", "database": "AGR" }, { "id": "F1Q5B0", "url": "https://omabrowser.org/oma/group/F1Q5B0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A3L7I8M5-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "Sh2d5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MQRAGAGARRASDCGPAPYRPRCIAKFAQYVGSFPVEDLDTQEGVYLVQQQLWALQDCSRRRAVILKFSLQGLKVYSGEGEVLLMAHALKRILYATWCPAACQFAFVARNPRSPASKLYCHLFVGSQPGEVHILYLLLCRSFQLAYLLQHPEERAQPEPCLGPMGDMSPKPLCSPGTPPVLVREPFSRDQLSQNVHALVSFRRVPAEGLLGGSGKELPEPEGRGGPRHTRLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAAWEAWPRSPGGPSCLVENEGSLTENIWAFAGLSKPCALALLRRDVHGAFLLWPEPGTSDQWSLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVESHAGMERSLFCPLSMGRLNPTYEEQDCGPEGRLPRTLRPLSHAKSEAELQGLG", "length": 429 }, "evidence": [ { "id": "F1Q5B0", "url": "https://omabrowser.org/oma/group/F1Q5B0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A8V0ZNL1-1", "protein_name": "SH2 domain containing 5", "gene_name": "SH2D5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MKKKMTANGRGPDPAPPPPRARGIAKSAEYVGSFMVEELELQQHVGQLEEQLRALKDCPRRRSVVLRFSLQGLKVYGDDGETLLMAHALRRILYSTCLHAERQFAFVARNPHSPPSTLFCHLFVSPVGEVHVLHLLLCRSFQLCYLQAHPELQAAEPDPPVLLRETLNPEEVSRNVNALLSLRRLPALGPLGAGHVFAQHLLQERRVEAEGRAVGWRPGNPYCSPVLVRKKAIRSKVLRSGAYRDCGAESQLQQREGGIGFGALKEDPGGQERDLGPDTHPPPSAPSGWESRGMRGLVLLPDTEAALAESVWAFAGIARASGIALLRGDVPGAFLLRPEPGATPRWCLWVHTPCGVVPYCVLRTQQGRFCVEHSHAEFRSMPALLAHYSAVPGGCFCRLSVGRCNPGYEQRDEDGPALVQHERG", "length": 424 }, "evidence": [ { "id": "F1Q5B0", "url": "https://omabrowser.org/oma/group/F1Q5B0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E1BA40-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "SH2D5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MQKAGAGGRRASDCGPAPQRPRCITKFAQYVGSFPVDDLDPQESVWLVQQQLWALKDCPRRRAVILKFSLQGLKIYSGEGEVLLMAHALRRILYATWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQLAYLLQHPEERARPEPCPEPVGDAPLKPVPGPGGPPGLVREPFGRDQLSQNVNALVSFRRLPAEGSGGSGKELLESASRGGTRHLRLGNPYCSPTLVRKKAIRSKVLRSGAYRACTYETQLQLSAREALPAAWEAWPRGPGGPSCLVESEGSLTENIWAFAGISRTSALALLRRDVLGAFLLWPEPGANGQWCLSVRTQCGVVPHQVFRNHVGRYCVEHLPAEFPSLEALVEHHAGTERSLFCSLDMGRLNPGYEEQDCGPSGQPPRTLRPLGHAKSEAELQGLG", "length": 428 }, "evidence": [ { "id": "F1Q5B0", "url": "https://omabrowser.org/oma/group/F1Q5B0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F1SU08-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "SH2D5", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MQKAGAGGRRASDCGPAPHRPRCITKFAQYVGSFPVDDLDTQERVWLVQQQLWALKDCPRRRAVILKFSLQGLKIYSGEGEVLLMAHALRRILYTTWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQLAYLLQHPEERAQPEPCLGPAGDVALKPLSCPGGPSGLVREPFGRDQLSQNVNALVSFRRLPAEGPGGSGKELPESESRGGARHTRLGNPYCSPTLVRKKAIRSKVIRSGAYRACTYETQLQLSAREAFPALWEAWPRGPGSPSCLVESEGSLTENIWAFAGISRPSALALLRRDVLGAFLLWPEPGANGQWCLSVRTQCGVVPHQVFRNHLGRYCVEHLPAEFPSLEALVEHHAGTERSLFCSLDMGRLNPN", "length": 396 }, "evidence": [ { "id": "F1Q5B0", "url": "https://omabrowser.org/oma/group/F1Q5B0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M9PEA4-1", "protein_name": "SH2 domain-containing protein", "gene_name": "Dmel\\CG10479", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGRLFQYNRFGATDGINKNTSKKDTQQKNKMLRNAIKCPGYSDIYGQYNKDSSFEKCDEWSNKLQFPAAGEMDKQEPIQSRTHKVYDSMKSFLQRKLFAQPSHKEQILNEEPTSDYDEQDLLDSSYHADAEEEEEERDADCSCSSTGSSSTSSSSPTTPKRSPQKSLLSLNCWQSSQPSSDSNPEEEQDEEAEEDSDAGISDCCQLLAENSPNTMSKRRRAAPLFTRYISANQNSDDDEDEEPELLACPWYQPRITAKAALEHLQQATPGSFLLRRSTPRHFELVLRLERNNKVKTYPVQSTRNQMYRLKGAKKQFTSLKALITHHSVMAEQLPLVLDMPRERHVVKPSSVRYADDFEPLESLQLLGILRSLQAKSIEI", "length": 379 }, "evidence": [ { "id": "HGNC:28819", "url": "https://alliancegenome.org/gene/HGNC:28819#orthology", "database": "AGR" }, { "id": "MGI:2446215", "url": "https://alliancegenome.org/gene/MGI:2446215#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q6ZV89-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "SH2D5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQKAGAGGRRASDCGLAPHRPRCITKFAQYVGSFPVDDLDTQESVWLVQQQLWALKDCPRRRAVILKFSLQGLKIYSGEGEVLLMAHALRRILYSTWCPADCQFAFMARNPRSPASKLFCHLFVGSQPGEVQILHLLLCRSFQLAYLLQHPEERAQPEPCPGPTGEVPLKPLSSSGGLVREPFGRDQLSQNVHALVSFRRLPAEGLVGSGKELPESEGRARHARLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAAWEAWPRGPGGHSCLVESEGSLTENIWAFAGISRPCALALLRRDVLGAFLLWPELGASGQWCLSVRTQCGVVPHQVFRNHLGRYCLEHLPAEFPSLEALVENHAVTERSLFCPLDMGRLNPTYEEQDCGPPGRPPRTLRPLSHAKSEAELQGLG", "length": 423 }, "evidence": [ { "id": "HGNC:28819", "url": "https://alliancegenome.org/gene/HGNC:28819#orthology", "database": "AGR" }, { "id": "MGI:2446215", "url": "https://alliancegenome.org/gene/MGI:2446215#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-67#orthology", "database": "AGR" }, { "id": "F1Q5B0", "url": "https://omabrowser.org/oma/group/F1Q5B0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8JZW5-1", "protein_name": "SH2 domain-containing protein 5", "gene_name": "Sh2d5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQRAGAGARRASDCGPAPYRPRCIAKLAQYVGSFPVDDLDTQESVGLVQQQLWALQDCSRRRAVILKFSLQGLKIYSGEGEVLLMAHALKRILYATWYPAACQFAFIARNPRSPSSKLFCHLFVGSQPGEVHILYLLLCRSFQLAYLLQHPEERAQSEPCLAPVGDLSLKPLCSPGVPPALVREPFSRDQLSQNVHALVSFRRLPAEGLLGSNGKELPESEGRGGTRHIRLGNPYCSPTLVRKKAIRSKVIRSGAYRGCTYETQLQLSAREAFPAAWEAWPRGPGGPSCLVENEGSLTENIWAFAGLSRSCALSLLRRDVHGAFLLWPEPGTSDQWSLSVRTQCGVVPHQVFRNHLGRFCLEHLPAEFPSLEALVESHAGVERSLFCPLSMGRLNPTYEEQDCGTEGRFPRTLRPLSHAKSEAELQGLG", "length": 429 }, "evidence": [ { "id": "HGNC:28819", "url": "https://alliancegenome.org/gene/HGNC:28819#orthology", "database": "AGR" }, { "id": "MGI:2446215", "url": "https://alliancegenome.org/gene/MGI:2446215#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-67", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-67#orthology", "database": "AGR" }, { "id": "F1Q5B0", "url": "https://omabrowser.org/oma/group/F1Q5B0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "postsynaptic density", "id": "GO:0014069", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0014069", "evidence": [ { "database": "UniProtKB", "id": "F1Q5B0", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1Q5B0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1Q5B0" }, { "id": "PS01179", "database": "PROSITE", "url": "https://prosite.expasy.org/PS01179" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PID", "eco_id": "ECO_0000259", "start_pos": 26, "end_pos": 148, "start_aa": "Val", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 217 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F496-1", "uniprot_ac": "E7F496", "uniprot_id": "E7F496_DANRE", "mass": { "chemical_mass": 31965.0, "monoisotopic_mass": 31965.0 }, "refseq": { "ac": "NP_001352955", "name": "GTPase IMAP family member 4 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352955" }, "gene_names": [ { "name": "gimap4", "type": "recommended", "evidence": [ { "id": "E7F496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F496" } ] }, { "name": "gimap4", "type": "synonym", "evidence": [ { "id": "NP_001352955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352955" } ] } ], "protein_names": [ { "name": "GTPase IMAP family member 4 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001352955", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352955" }, { "id": "E7F496", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F496/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01017562.1, GDQH01015904.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476818 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Sep 20, 2018 this sequence version replaced XP_002666654.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001352955", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352955" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F496", "url": "https://www.uniprot.org/uniprotkb/E7F496" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gimap4", "url": "https://www.uniprot.org/uniprotkb/E7F496", "locus": {} } ], "crossref": [ { "id": "cd01852", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01852", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "793765", "url": "https://www.ncbi.nlm.nih.gov/gene/793765", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006703", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006703", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:793765", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793765", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7F496", "url": "https://www.orthodb.org/?gene=E7F496", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10903", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10903:SF168", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10903:SF168", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04548", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04548", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001352955", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352955", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB13A9X7", "url": "https://www.uniprot.org/uniprotkb/A0AB13A9X7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB13A9X7-1", "url": "https://www.uniprot.org/uniprotkb/A0AB13A9X7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F496", "url": "https://www.uniprot.org/uniprotkb/E7F496", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F496-1", "url": "https://www.uniprot.org/uniprotkb/E7F496-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MSSNRSPNTAADDRLDPEEDKQLAAATREANRLPELRLILLGWRWPGKSLTGNTILGREEFRLERAAEFCVKRETEIDLRQVTVVDTPGWFSAQTTPADYQQEMVRSVSMLQPGPHAFLLVIPVGMFTETDRARIEENLALFGEDVWKHTLVVFTWAEILKDRSIERHIRREGRDLQWVLDKCKKRYHVINNYIFGEHPQLPQLMEKVEKIVAEEGGCFILKQDEIKTQNQLQSLNLNSNSVKENRELGARPKQNGSCNSLRSMDVDPPQNLVEEVSD", "length": 278, "header": "tr|E7F496-1|E7F496_DANRE Isoform 1 of GTPase IMAP family member 4 isoform 1 OS=Danio rerio OX=7955 GN=gimap4 PE=3 SV=2 CANONICAL=E7F496-1" }, "isoforms": [ { "isoform_ac": "A0AB13A9X7-1", "url": "https://www.uniprot.org/uniprotkb/E7F496/entry#A0AB13A9X7-1", "sequence": { "sequence": "MSSNRSPNTAADDRLDPEEDKQLAAATREANRLPELRLILLGWRWPGKSLTGNTILGREEFRLERAAEFCVKRETEIDLRQVTVVDTPGWFSAQTTPADYQQEMVRSVSMLQPGPHAFLLVIPVGMFTETDRARIEENLALFGEDVWKHTLVVFTWAEILKDRSIERHIRREGRDLQWVLDKCKKRYHVINNYIFGEHPQLPQLMEKVEKIVAEEGGCFILKQDEIKTQNQLQSLNLNSNSVKENRELGARPKQNGSCNSLRSMDVDPPQKERNS", "length": 275, "header": "tr|A0AB13A9X7-1|E7F496_DANRE Computationally mapped isoform of GTPase IMAP family member 4 isoform 1 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Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068069930", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068069930" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F6Q4", "url": "https://www.uniprot.org/uniprotkb/E7F6Q4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-152b24.6", "url": "https://www.uniprot.org/uniprotkb/E7F6Q4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100922-31", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100922-31", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100002310", "url": "https://www.ncbi.nlm.nih.gov/gene/100002310", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000909", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000909", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017946", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017946", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051057", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051057", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100002310", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100002310", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7F6Q4", "url": "https://www.orthodb.org/?gene=E7F6Q4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13593", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13593", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13593:SF147", "url": 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"total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E9QGB9-1", "uniprot_ac": "E9QGB9", "uniprot_id": "E9QGB9_DANRE", "mass": { "chemical_mass": 30177.0, "monoisotopic_mass": 30177.0 }, "refseq": { "ac": "NP_001315146", "name": "Transmembrane protein 150A-like isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315146" }, "gene_names": [ { "name": "zgc:154058", "type": "recommended", "evidence": [ { "id": "E9QGB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QGB9" } ] }, { "name": "zgc:154058", "type": "synonym", "evidence": [ { "id": "NP_001315146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315146" }, { "id": "E9QGB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QGB9" } ] } ], "protein_names": [ { "name": "Transmembrane protein 150A-like isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001315146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315146" }, { "id": "E9QGB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QGB9/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01045446.1, SRR26395062.1511387.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505383 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Jun 9, 2016 this sequence version replaced XP_005156753.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence because no single transcript was available for the full length of the gene. The extent of this transcript is supported by partial transcript CK870089.1, and RNA-seq and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001315146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315146" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QGB9", "url": "https://www.uniprot.org/uniprotkb/E9QGB9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/E9QGB9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060929-48", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060929-48", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000069795", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000069795", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "795538", "url": "https://www.ncbi.nlm.nih.gov/gene/795538", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:795538", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795538", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SITGMWI", "url": "https://omabrowser.org/oma/group/SITGMWI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8A694", "url": "https://www.orthodb.org/?gene=B8A694", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E9QGB9", "url": "https://www.orthodb.org/?gene=E9QGB9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21324:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21324:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001315146", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315146", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32T6K7", "url": "https://www.uniprot.org/uniprotkb/A0AB32T6K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T6K7-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T6K7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2A6", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2A6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2A6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2A6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2A7", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2A7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2A7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2A7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2A8", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2A8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2B2", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2B2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2B2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2B2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2B3", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2B3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H2B3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H2B3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A694", "url": "https://www.uniprot.org/uniprotkb/B8A694", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A694-1", "url": "https://www.uniprot.org/uniprotkb/B8A694-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QGB9", "url": "https://www.uniprot.org/uniprotkb/E9QGB9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QGB9-1", "url": "https://www.uniprot.org/uniprotkb/E9QGB9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060929-48", "url": "https://zfin.org/ZDB-GENE-060929-48", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSLWMILPVSLPALTITGIWVVYAMALYNQHVCPVDNWMYNQSCEEDLVMQRGPTLCCTLDNVPLISKCGTLPPESCFFSLICSTGSFMVMVIVLLRYAHVIEKHQNCVLNTASLSTGWICAAGLIMVGNFQVDYAKVLHYVGAGVAFPTSMLFVCLQSALTYRLAKTQGEYNMGHLRLFMTLLAFVALVLSGVFFVQESFILQHASAIFEWVFCVIIMLFYGTFAFEFAGISSDTMMVLARGQSLPSVSRDHKMESLSGANQHQPESLSIL", "length": 272, "header": "tr|E9QGB9-1|E9QGB9_DANRE Isoform 1 of Transmembrane protein 150A-like isoform 1 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=E9QGB9-1" }, "isoforms": [ { "isoform_ac": "A0AB32T6K7-1", "url": "https://www.uniprot.org/uniprotkb/E9QGB9/entry#A0AB32T6K7-1", "sequence": { "sequence": "MSRGRQAGEGERSGCFEGSSRGSCAGDVSVDDLTRQPPSSHHHWNMGRVSAWYAMALYNQHVCPVDNWMYNQSCEEDLVMQRGPTLCCTLDNVPLISKCGTLPPESCFFSLICSTGSFMVMVIVLLRYAHVIEKHQNCVLNTASLSTGWICAAGLIMVGNFQVDYAKVLHYVGAGVAFPTSMLFVCLQSALTYRLAKTQGEYNMGHLRLFMTLLAFVALVLSGVFFVQESFILQHASAIFEWVFCVIIMLFYGTFAFEFAGISSDTMMVLARGQSLPSVSRDHKMESLSGANQHQPESLSIL", "length": 302, "header": "tr|A0AB32T6K7-1|E9QGB9_DANRE Computationally mapped isoform of Transmembrane protein 150A-like isoform 1 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=E9QGB9-1" }, "locus": {} }, { "isoform_ac": "A0AC58H2A6-1", "url": "https://www.uniprot.org/uniprotkb/E9QGB9/entry#A0AC58H2A6-1", "sequence": { "sequence": "MYAMALYNQHVCPVDNWMYNQSCEEDLVMQRGPTLCCTLDNVPLISKCGTLPPESCFFSLICSTGSFMVMVIVLLRYAHVIEKHQNCVLNTASLSTGWICAAGLIMVGNFQVDYAKVLHYVGAGVAFPTSMLFVCLQSALTYRLAKTQGEYNMGHLRLFMTLLAFVALVLSGVFFVQESFILQHASAIFEWVFCVIIMLFYGTFAFEFAGISSDTMMVLARGQSLPSVSRDHKMESLSGANQHQPESLSIL", "length": 251, "header": "tr|A0AC58H2A6-1|A0AC58H2A6_DANRE Computationally mapped isoform of Transmembrane protein 150A-like isoform X3 OS=Danio rerio OX=7955 GN=zgc:154058 PE=3 SV=1 CANONICAL=E9QGB9-1" }, "locus": {} }, { "isoform_ac": "A0AC58H2A7-1", "url": "https://www.uniprot.org/uniprotkb/E9QGB9/entry#A0AC58H2A7-1", "sequence": { "sequence": "MSLWMILPVSLPALTITGIWVVMYNQSCEEDLVMQRGPTLCCTLDNVPLISKCGTLPPESCFFSLICSTGSFMVMVIVLLRYAHVIEKHQNCVLNTASLSTGWICAAGLIMVGNFQVDYAKVLHYVGAGVAFPTSMLFVCLQSALTYRLAKTQGEYNMGHLRLFMTLLAFVALVLSGVFFVQESFILQHASAIFEWVFCVIIMLFYGTFAFEFAGISSDTMMVLARGQSLPSVSRDHKMESLSGANQHQPESLSIL", "length": 256, "header": "tr|A0AC58H2A7-1|A0AC58H2A7_DANRE Computationally mapped isoform of Transmembrane protein 150A-like isoform X2 OS=Danio rerio OX=7955 GN=zgc:154058 PE=3 SV=1 CANONICAL=E9QGB9-1" }, "locus": {} }, { "isoform_ac": "A0AC58H2A8-1", "url": "https://www.uniprot.org/uniprotkb/E9QGB9/entry#A0AC58H2A8-1", "sequence": { "sequence": "MSRGRQAGEGERSGCFEGSSRGSCAGDVSVDDLTRQPPSSHHHWNMGRVSAWYAMALYNQHVCPVDNWMYNQSCEEDLVMQRGPTLCCTLDNVPLISKCGTLPPESCFFSLICSTGSFMVMVIVLLRYAHVIEKHQNCVLNTASLSTGWICAAGLIMVGNFQSKELP", "length": 167, "header": "tr|A0AC58H2A8-1|A0AC58H2A8_DANRE Computationally mapped isoform of Transmembrane protein 150A-like isoform X6 OS=Danio rerio OX=7955 GN=zgc:154058 PE=3 SV=1 CANONICAL=E9QGB9-1" }, "locus": {} }, { "isoform_ac": "A0AC58H2B2-1", "url": "https://www.uniprot.org/uniprotkb/E9QGB9/entry#A0AC58H2B2-1", "sequence": { "sequence": "MYNQSCEEDLVMQRGPTLCCTLDNVPLISKCGTLPPESCFFSLICSTGSFMVMVIVLLRYAHVIEKHQNCVLNTASLSTGWICAAGLIMVGNFQVDYAKVLHYVGAGVAFPTSMLFVCLQSALTYRLAKTQGEYNMGHLRLFMTLLAFVALVLSGVFFVQESFILQHASAIFEWVFCVIIMLFYGTFAFEFAGISSDTMMVLARGQSLPSVSRDHKMESLSGANQHQPESLSIL", "length": 234, "header": "tr|A0AC58H2B2-1|A0AC58H2B2_DANRE Computationally mapped isoform of Transmembrane protein 150A-like isoform X4 OS=Danio rerio OX=7955 GN=zgc:154058 PE=3 SV=1 CANONICAL=E9QGB9-1" }, "locus": {} }, { "isoform_ac": "A0AC58H2B3-1", "url": "https://www.uniprot.org/uniprotkb/E9QGB9/entry#A0AC58H2B3-1", "sequence": { "sequence": "MVMVIVLLRYAHVIEKHQNCVLNTASLSTGWICAAGLIMVGNFQVDYAKVLHYVGAGVAFPTSMLFVCLQSALTYRLAKTQGEYNMGHLRLFMTLLAFVALVLSGVFFVQESFILQHASAIFEWVFCVIIMLFYGTFAFEFAGISSDTMMVLARGQSLPSVSRDHKMESLSGANQHQPESLSIL", "length": 184, "header": "tr|A0AC58H2B3-1|A0AC58H2B3_DANRE Computationally mapped isoform of Transmembrane protein 150A-like isoform X5 OS=Danio rerio OX=7955 GN=zgc:154058 PE=3 SV=1 CANONICAL=E9QGB9-1" }, "locus": {} }, { "isoform_ac": "B8A694-1", "url": "https://www.uniprot.org/uniprotkb/E9QGB9/entry#B8A694-1", "sequence": { "sequence": "MSLWMILPVSLPALTITGIWVVYAMALYNQHVCPVDNWMYNQSCEEDLVMQRGPTLCCTLDNVPLISKCGTLPPESCFFSLICSTGSFMVMVIVLLRYAHVIEKHQNCVLNTASLSTGWICAAGLIMVGNFQSKELP", "length": 137, "header": "tr|B8A694-1|B8A694_DANRE Computationally mapped isoform of Transmembrane protein 150A-like isoform 2 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=E9QGB9-1" }, "locus": {} }, { "isoform_ac": "E9QGB9-1", "url": "https://www.uniprot.org/uniprotkb/E9QGB9/entry#E9QGB9-1", "sequence": { "sequence": "MSLWMILPVSLPALTITGIWVVYAMALYNQHVCPVDNWMYNQSCEEDLVMQRGPTLCCTLDNVPLISKCGTLPPESCFFSLICSTGSFMVMVIVLLRYAHVIEKHQNCVLNTASLSTGWICAAGLIMVGNFQVDYAKVLHYVGAGVAFPTSMLFVCLQSALTYRLAKTQGEYNMGHLRLFMTLLAFVALVLSGVFFVQESFILQHASAIFEWVFCVIIMLFYGTFAFEFAGISSDTMMVLARGQSLPSVSRDHKMESLSGANQHQPESLSIL", "length": 272, "header": "tr|E9QGB9-1|E9QGB9_DANRE Isoform 1 of Transmembrane protein 150A-like isoform 1 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=E9QGB9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8A694", "url": "https://www.uniprot.org/uniprotkb/B8A694" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "The novel human HtrA2 ortholog in zebrafish: New molecular insight and challenges into the imbalance of homeostasis.", "journal": "Gene", "date": "2022", "authors": "Nam Min-Kyung, Moon Jeong-Mi, Kim Goo-Young, Kim Sung Min, Rhim Hyangshuk", "evidence": [ { "database": "UniProtKB", "id": "B8A694", "url": "https://www.uniprot.org/uniprotkb/B8A694" } ], "reference": [ { "type": "PubMed", "id": "35121025", "url": "https://glygen.org/publication/PubMed/35121025" } ] } ], "pathway": [ { "id": "dre:795538", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795538", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "E1C9H3-1", "protein_name": "Transmembrane protein 150B", "gene_name": "TMEM150B", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPAWAILPVMLPAFTITGMWIVYAMALSNNHICPVHNWNYNQSCGLDSPGSCCTLDHIPLVSKCGTLPPESCFFSLICSLGSFMVILVGLLRYAHVLERVGPSLLNTLGLAAGWLCAAGLTMVGNFQVDHAKVLHYIGAGVAFPTSMLFVFLQSVLTYRAAKTRGHYWTGHLRSILTAMAFVTLVFSGVFFIQESFVLQHVAALCEWVFIIDVLVFYGTFTFEFGAISTDTFLVLLRASRAPKSHKGEDSLPGTEGLPML", "length": 260 }, "evidence": [ { "id": "E9QGB9", "url": "https://omabrowser.org/oma/group/E9QGB9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "E9QGB9", "url": "https://www.uniprot.org/uniprotkb/E9QGB9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 41, "end_pos": 43, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E9QGB9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QGB9" }, { "id": "PF10277", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10277" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "CWH43-like N-terminal", "eco_id": "ECO_0000259", "start_pos": 4, "end_pos": 231, "start_aa": "Trp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 41, "end_pos": 43 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7FBQ2-1", "uniprot_ac": "E7FBQ2", "uniprot_id": "E7FBQ2_DANRE", "mass": { "chemical_mass": 320799.0, "monoisotopic_mass": 320799.0 }, "refseq": { "ac": "XP_001338900", "name": "uncharacterized protein si:ch211-281l24.3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338900" }, "gene_names": [ { "name": "si:ch211-281l24.3", "type": "recommended", "evidence": [ { "id": "E7FBQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FBQ2" } ] }, { "name": "si:ch211-281l24.3", "type": "synonym", "evidence": [ { "id": "XP_001338900", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338900" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch211-281l24.3 isoform X1", "type": "synonym", "evidence": [ { "id": "E7FBQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FBQ2/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch211-281l24.3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001338900", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338900" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001338900.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001338900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338900" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FBQ2", "url": "https://www.uniprot.org/uniprotkb/E7FBQ2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-281l24.3", "url": "https://www.uniprot.org/uniprotkb/E7FBQ2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131121-575", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-575", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000068637", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000068637", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00063", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00063", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19802", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19802", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "798456", "url": "https://www.ncbi.nlm.nih.gov/gene/798456", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003961", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003961", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040581", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040581", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048997", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048997", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:798456", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798456", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7FBQ2", "url": "https://www.orthodb.org/?gene=E7FBQ2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31594", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31594", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31594:SF16", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31594:SF16", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF18078", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF18078", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21109", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21109", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001338900", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338900", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32T751", "url": "https://www.uniprot.org/uniprotkb/A0AB32T751", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32T751-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32T751-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FBQ2", "url": "https://www.uniprot.org/uniprotkb/E7FBQ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FBQ2-1", "url": "https://www.uniprot.org/uniprotkb/E7FBQ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131121-575", "url": "https://zfin.org/ZDB-GENE-131121-575", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPVQRKFFDSQFQHPPALQQANGLNWAKQSYSLRTNGEPSPGPTLPQSSVLYNGAGVMGENERPDEAPSPAASYCSFKSNHSVDCLTTFSDTTQIHGVKRMQQDEMLFTLPSNLTMDYAQSVDQQTMLNDPTQHAVADNIFLKSLSGMRAYVRTSPAPSYMSAKSDQSIDRPIVFTNETDHNYMNLISHEAASSAASLTSWESDQSDCLTQWERTELSYTRKRQFETTSPAPSTLSLQSHQSMDRPAVFKNENQQQCKAASPAPTLTSLKSELSMDRPIVFGKKQSARLKSERPDEAPSPVTSLFSLNSISSMDRPIVFNDKTQHNNVDRLLESVRQLNEGLSQKYMEYERKRQFETTSPAPSTLSLQSHQSMDRPAVFKNENQQQCKAASPAPTLTSLKSELSMDRPIVFGKKQSERLKSERPDEAPSPVTSLFSLNSISSMDRPIVFNDKTQHNNVDRLKPCKAASPEPSKTESLKIEQSQSCSTISATLLTEDHYRCLVCSQVFKDPVSLPCGHSCCKHCFWSCNNKPKSYSCPQCSKRFRGRPMLNVNVALANLIEELKRAGFSPVLPAKCFAGFEDVACDICTERKLKAVKSCLTCTASYCETHVRQHYTVPALQRHKLVEAIRLPQKDGKSQEDDLKAALKERDMQAKRLCGGFEIHCIDFSDVIEMAALHHSLSLGMLYDSHSNSFLQDIMLEEDSVASMKVSLPRPQTCVKILECDSFQDRCRALDISSSMLQKSKSVLAKLSGAAAFLNHPEQSQNQDRVTLHYRTTTRLDMISQRLLEEVTLPSVINETTATHVIIGVCYGAQAVFVFDDSNQGISEKRSTEMKNIIKKITTSISARDVFLSLSETEKATTISHDCNLYIDMGDWTNPVSIEKALEIYDSLPSLLGPKGEKAVPLKVWLYPLDKEDKSSVSAAVSGVSENLHEAEKILGDLRKQIKICQDMITDCNNFMVIMWFPAIKEKLVQFLDFLQEYKNNFHRRIAESMHMIKQEPEMSWQHFLESHYKSPFHAEKTNRWLENKETELKILNDCKAADITVVKSQAELQHIISHPQKKEVLCLNLFSPDAEDVYLSVLRKHINCDHMTSHDSLLTNLTDVHLFIASKETNEDEEQTKFIAAAVPDKDFPKYSVQFYHAQRIVSRNVMLGTNPDIAQIVQIKHTSVSLKLILQQAKSNVRYVVQYRALENDGKNYTSWNHDIVEDPTLKRTCIISNLKSGYHYQLRYSVIENDRMSSFSKIIHFQTAVAATPGDPLVNKPNTDTLRVTWQKAEADEDCPVLHYMVEYKEAGLEGWSAVQTQGPECECTLTVPHSTCYRVRVSAVYEDAISKTTSETEVPVDVWRIKLSERKISILQEVLKIQTEKKPVELIDWTDEESEVRGFLQCLPYISELRFAASHNESSDLYSKKFILDVCLQAALCQKKTEDETVKILLSSVDYEKSDFLLDLYSHVKDYEKQTGKCVLPALKLFYQSAPAVWSIDLSQRKSTFFLEVLKLQTEKKPVELRGWTDEESEVREFIQCLPYISQLRFYSFPLCKERTVQFLVNLIVTASKYNTIKENYTDLLTSVCSYSTFPFDEKYFSVQANQCDFLLDLYSHVKDNESQTGKIVLQALRPVYQSAPAVWRINLSKRKSSLLLEVLKLQTEKKPVELIDWTDEESEVRGFIQCLPYISHLRFHAAPKESSQPWNRRKRFILDVCLQAAFCQKETVELTFKILLSSVNYEKSAFLLDLYSHVKDYESQTDKIVLPALQSVYQSAAPEVWRIDLSQKKSSILLEVLKLQTEKKTVELIDLTNDNIEVNIFLRCLPYISELRFVSSQNESVELRNKRKRFILDVCFQAALCQKNTEDETVKILLSSLNYEKSDFLLDLYSHVKDYEKQTGKCVLPALKLFYQSAPAVWSIDLSQRKSTFFLEVVKLQTEKKPVELRGWTDDHLEINRFLLCLPYISQLRFYSTQNESAELWGSRKRFMLDLCLNAALYQKKTIDTAVKILLSSVDYEKSDFLLDLCSHVKDYEKQKGKCVLPALKPFYQSAPAVWSIDLSQRKISILLEVLKLQTEKKPVELIDWTDEESEVRGFIQCLPYISELRFCHCVFSKKRPFQFLVNLIVAASGSNEIGAGKNYTDLLTSVCSYSTFPFDERNFSVQANQCDFLLDLCSHVKDYESQTGRSVLPALQPVYQSASPAVWRINLFERKSSILLEVLKLQTEKKPVELIDWTDNESEAREFLKCLPYISQLRNADHYFPSLCKVSSIKADKVTLLQALDCTITLSGKLPSSTCRSVGKVLGLSSSKLNLTLKPQAISIRGLKLLLRPIKQLQKLSVEDKFLLKMVRVLRSINYRFPLATEKLSLDTNDSEQNHLHILSSLTSLLRLMSVKCLDLSQCKSEALTFTALLCLQEHLTLRFSQETLQQLISVVYKAQDDLLTSFFLKRVSKDLTFCSLNWEVIHYLVQCHMQNFKLDLSKRKISCENIKEFLPWLSRIHWKRLSPSLTLSIIMEIYESRFPEYVSSLMSSAGNYINLNGRVLDSVHCAALRFTLEHCNTLKLNLLWTSIPEEELKSILPLFNRVTQLSVDRLLLLKLLHCCSSTDVQQEAAAALLSALKNTLDFSCSTALDLTDTEENQEHFNLSIKDSSIISSVLQKTLNVKLILKDCELSDEALKQLWPILPKVQLSCSKALLLQFLACISKDRAERRCLRSAEALSQALGEEMDLSHTQMDQRSCEQLAVFLEYSEGLTELDLSHCKLTDQCMEPLLPHLHKTQTLDLSHNNITDESANKIHSIVSNHSNIQTVRLFGNRINDRKQFIKDKRFEIW", "length": 2813, "header": "tr|E7FBQ2-1|E7FBQ2_DANRE Isoform 1 of Uncharacterized protein si:ch211-281l24.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-281l24.3 PE=4 SV=1 CANONICAL=E7FBQ2-1" }, "isoforms": [ { "isoform_ac": "A0AB32T751-1", "url": "https://www.uniprot.org/uniprotkb/E7FBQ2/entry#A0AB32T751-1", "sequence": { "sequence": "MPVQRKFFDSQFQHPPALQQANGLNWAKQSYSLRTNGEPSPGPTLPQSSVLYNGAGVMGENERPDEAPSPAASYCSFKSNHSVDCLTTFSDTTQIHGVKRMQQDEMLFTLPSNLTMDYAQSVDQQTMLNDPTQHAVADNIFLKSLSGMRAYVRTSPAPSYMSAKSDQSIDRPIVFTNETDHNYMNLISHEAASSAASLTSWESDQSDCLTQWERTELSYTRKRQFETTSPAPSTLSLQSHQSMDRPAVFKNENQQQCKAASPAPTLTSLKSELSMDRPIVFGKKQSARLKSERPDEAPSPVTSLFSLNSISSMDRPIVFNDKTQHNNVDRLLESVRQLNEGLSQKYMEYERKRQFETTSPAPSTLSLQSHQSMDRPAVFKNENQQQCKAASPAPTLTSLKSELSMDRPIVFGKKQSERLKSERPDEAPSPVTSLFSLNSISSMDRPIVFNDKTQHNNVDRLKPCKAASPEPSKTESLKIEQSQSCSTISATLLTEDHYRCLVCSQVFKDPVSLPCGHSCCKHCFWSCNNKPKSYSCPQCSKRFRGRPMLNVNVALANLIEELKRAGFSPVLPAKCFAGFEDVACDICTERKLKAVKSCLTCTASYCETHVRQHYTVPALQRHKLVEAIRLPQKDGKSQEDDLKAALKERDMQAKRLCGGFEIHCIDFSDVIEMAALHHSLSLGMLYDSHSNSFLQDIMLEEDSVASMKVSLPRPQTCVKILECDSFQDRCRALDISSSMLQKSKSVLAKLSGAAAFLNHPEQSQNQDRVTLHYRTTTRLDMISQRLLEEVTLPSVINETTATHVIIGVCYGAQAVFVFDDSNQGISEKRSTEMKNIIKKITTSISARDVFLSLSETEKATTISHDCNLYIDMGDWTNPVSIEKALEIYDSLPSLLGPKGEKAVPLKVWLYPLDKEDKSSVSAAVSGVSENLHEAEKILGDLRKQIKICQDMITDCNNFMVIMWFPAIKEKLVQFLDFLQEYKNNFHRRIAESMHMIKQEPEMSWQHFLESHYKSPFHAEKTNRWLENKETELKILNDCKAADITVVKSQAELQHIISHPQKKEVLCLNLFSPDAEDVYLSVLRKHINCDHMTSHDSLLTNLTDVHLFIASKETNEDEEQTKFIAAAVPDKDFPKYSVQFYHAQRIVSRNVMLGTNPDIAQIVQIKHTSVSLKLILQQAKSNVRYVVQYRALENDGKNYTSWNHDIVEDPTLKRTCIISNLKSGYHYQLRYSVIENDRMSSFSKIIHFQTAVAATPGDPLVNKPNTDTLRVTWQKAEADEDCPVLHYMVEYKEAGLEGWSAVQTQGPECECTLTVPHSTCYRVRVSAVYEDAISKTTSETEVPVDVWRIKLSERKISILQEVLKIQTEKKPVELIDWTDEESEVRGFLQCLPYISELRFAASHNESSDLYSKKFILDVCLQAALCQKKTEDETVKILLSSVDYEKSDFLLDLYSHVKDYEKQTGKCVLPALKLFYQSAPAVWSIDLSQRKSTFFLEVLKLQTEKKPVELRGWTDEESEVREFIQCLPYISQLRFYSFPLCKERTVQFLVNLIVTASKYNTIKENYTDLLTSVCSYSTFPFDEKYFSVQANQCDFLLDLYSHVKDNESQTGKIVLQALRPVYQSAPAVWRINLSKRKSSLLLEVLKLQTEKKPVELIDWTDEESEVRGFIQCLPYISHLRFHAAPKESSQPWNRRKRFILDVCLQAAFCQKETVELTFKILLSSVNYEKSAFLLDLYSHVKDYESQTDKIVLPALQSVYQSAAPEVWRIDLSQKKSSILLEVLKLQTEKKTVELIDLTNDNIEVNIFLRCLPYISELRFVSSQNESVELRNKRKRFILDVCFQAALCQKNTEDETVKILLSSLNYEKSDFLLDLYSHVKDYEKQTGKCVLPALKLFYQSAPAVWSIDLSQRKSTFFLEVVKLQTEKKPVELRGWTDDHLEINRFLLCLPYISQLRFYSTQNESAELWGSRKRFMLDLCLNAALYQKKTIDTAVKILLSSVDYEKSDFLLDLCSHVKDYEKQKGKCVLPALKPFYQSAPAVWSIDLSQRKISILLEVLKLQTEKKPVELIDWTDEESEVRGFIQCLPYISELRFCHCVFSKKRPFQFLVNLIVAASGSNEIGAGKNYTDLLTSVCSYSTFPFDERNFSVQANQCDFLLDLCSHVKDYESQTGRSVLPALQPVYQSASPAVWRINLFERKSSILLEVLKLQTEKKPVELIDWTDNESEAREFLKCLPYISQLSVEDKFLLKMVRVLRSINYRFPLATEKLSLDTNDSEQNHLHILSSLTSLLRLMSVKCLDLSQCKSEALTFTALLCLQEHLTLRFSQETLQQLISVVYKAQDDLLTSFFLKRVSKDLTFCSLNWEVIHYLVQCHMQNFKLDLSKRKISCENIKEFLPWLSRIHWKRLSPSLTLSIIMEIYESRFPEYVSSLMSSAGNYINLNGRVLDSVHCAALRFTLEHCNTLKLNLLWTSIPEEELKSILPLFNRVTQLSVDRLLLLKLLHCCSSTDVQQEAAAALLSALKNTLDFSCSTALDLTDTEENQEHFNLSIKDSSIISSVLQKTLNVKLILKDCELSDEALKQLWPILPKVQLSCSKALLLQFLACISKDRAERRCLRSAEALSQALGEEMDLSHTQMDQRSCEQLAVFLEYSEGLTELDLSHCKLTDQCMEPLLPHLHKTQTLDLSHNNITDESANKIHSIVSNHSNIQTVRLFGNRINDRKQFIKDKRFEIW", "length": 2730, "header": "tr|A0AB32T751-1|E7FBQ2_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-281l24.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-281l24.3 PE=4 SV=1 CANONICAL=E7FBQ2-1" }, "locus": {} }, { "isoform_ac": "E7FBQ2-1", "url": "https://www.uniprot.org/uniprotkb/E7FBQ2/entry#E7FBQ2-1", "sequence": { "sequence": "MPVQRKFFDSQFQHPPALQQANGLNWAKQSYSLRTNGEPSPGPTLPQSSVLYNGAGVMGENERPDEAPSPAASYCSFKSNHSVDCLTTFSDTTQIHGVKRMQQDEMLFTLPSNLTMDYAQSVDQQTMLNDPTQHAVADNIFLKSLSGMRAYVRTSPAPSYMSAKSDQSIDRPIVFTNETDHNYMNLISHEAASSAASLTSWESDQSDCLTQWERTELSYTRKRQFETTSPAPSTLSLQSHQSMDRPAVFKNENQQQCKAASPAPTLTSLKSELSMDRPIVFGKKQSARLKSERPDEAPSPVTSLFSLNSISSMDRPIVFNDKTQHNNVDRLLESVRQLNEGLSQKYMEYERKRQFETTSPAPSTLSLQSHQSMDRPAVFKNENQQQCKAASPAPTLTSLKSELSMDRPIVFGKKQSERLKSERPDEAPSPVTSLFSLNSISSMDRPIVFNDKTQHNNVDRLKPCKAASPEPSKTESLKIEQSQSCSTISATLLTEDHYRCLVCSQVFKDPVSLPCGHSCCKHCFWSCNNKPKSYSCPQCSKRFRGRPMLNVNVALANLIEELKRAGFSPVLPAKCFAGFEDVACDICTERKLKAVKSCLTCTASYCETHVRQHYTVPALQRHKLVEAIRLPQKDGKSQEDDLKAALKERDMQAKRLCGGFEIHCIDFSDVIEMAALHHSLSLGMLYDSHSNSFLQDIMLEEDSVASMKVSLPRPQTCVKILECDSFQDRCRALDISSSMLQKSKSVLAKLSGAAAFLNHPEQSQNQDRVTLHYRTTTRLDMISQRLLEEVTLPSVINETTATHVIIGVCYGAQAVFVFDDSNQGISEKRSTEMKNIIKKITTSISARDVFLSLSETEKATTISHDCNLYIDMGDWTNPVSIEKALEIYDSLPSLLGPKGEKAVPLKVWLYPLDKEDKSSVSAAVSGVSENLHEAEKILGDLRKQIKICQDMITDCNNFMVIMWFPAIKEKLVQFLDFLQEYKNNFHRRIAESMHMIKQEPEMSWQHFLESHYKSPFHAEKTNRWLENKETELKILNDCKAADITVVKSQAELQHIISHPQKKEVLCLNLFSPDAEDVYLSVLRKHINCDHMTSHDSLLTNLTDVHLFIASKETNEDEEQTKFIAAAVPDKDFPKYSVQFYHAQRIVSRNVMLGTNPDIAQIVQIKHTSVSLKLILQQAKSNVRYVVQYRALENDGKNYTSWNHDIVEDPTLKRTCIISNLKSGYHYQLRYSVIENDRMSSFSKIIHFQTAVAATPGDPLVNKPNTDTLRVTWQKAEADEDCPVLHYMVEYKEAGLEGWSAVQTQGPECECTLTVPHSTCYRVRVSAVYEDAISKTTSETEVPVDVWRIKLSERKISILQEVLKIQTEKKPVELIDWTDEESEVRGFLQCLPYISELRFAASHNESSDLYSKKFILDVCLQAALCQKKTEDETVKILLSSVDYEKSDFLLDLYSHVKDYEKQTGKCVLPALKLFYQSAPAVWSIDLSQRKSTFFLEVLKLQTEKKPVELRGWTDEESEVREFIQCLPYISQLRFYSFPLCKERTVQFLVNLIVTASKYNTIKENYTDLLTSVCSYSTFPFDEKYFSVQANQCDFLLDLYSHVKDNESQTGKIVLQALRPVYQSAPAVWRINLSKRKSSLLLEVLKLQTEKKPVELIDWTDEESEVRGFIQCLPYISHLRFHAAPKESSQPWNRRKRFILDVCLQAAFCQKETVELTFKILLSSVNYEKSAFLLDLYSHVKDYESQTDKIVLPALQSVYQSAAPEVWRIDLSQKKSSILLEVLKLQTEKKTVELIDLTNDNIEVNIFLRCLPYISELRFVSSQNESVELRNKRKRFILDVCFQAALCQKNTEDETVKILLSSLNYEKSDFLLDLYSHVKDYEKQTGKCVLPALKLFYQSAPAVWSIDLSQRKSTFFLEVVKLQTEKKPVELRGWTDDHLEINRFLLCLPYISQLRFYSTQNESAELWGSRKRFMLDLCLNAALYQKKTIDTAVKILLSSVDYEKSDFLLDLCSHVKDYEKQKGKCVLPALKPFYQSAPAVWSIDLSQRKISILLEVLKLQTEKKPVELIDWTDEESEVRGFIQCLPYISELRFCHCVFSKKRPFQFLVNLIVAASGSNEIGAGKNYTDLLTSVCSYSTFPFDERNFSVQANQCDFLLDLCSHVKDYESQTGRSVLPALQPVYQSASPAVWRINLFERKSSILLEVLKLQTEKKPVELIDWTDNESEAREFLKCLPYISQLRNADHYFPSLCKVSSIKADKVTLLQALDCTITLSGKLPSSTCRSVGKVLGLSSSKLNLTLKPQAISIRGLKLLLRPIKQLQKLSVEDKFLLKMVRVLRSINYRFPLATEKLSLDTNDSEQNHLHILSSLTSLLRLMSVKCLDLSQCKSEALTFTALLCLQEHLTLRFSQETLQQLISVVYKAQDDLLTSFFLKRVSKDLTFCSLNWEVIHYLVQCHMQNFKLDLSKRKISCENIKEFLPWLSRIHWKRLSPSLTLSIIMEIYESRFPEYVSSLMSSAGNYINLNGRVLDSVHCAALRFTLEHCNTLKLNLLWTSIPEEELKSILPLFNRVTQLSVDRLLLLKLLHCCSSTDVQQEAAAALLSALKNTLDFSCSTALDLTDTEENQEHFNLSIKDSSIISSVLQKTLNVKLILKDCELSDEALKQLWPILPKVQLSCSKALLLQFLACISKDRAERRCLRSAEALSQALGEEMDLSHTQMDQRSCEQLAVFLEYSEGLTELDLSHCKLTDQCMEPLLPHLHKTQTLDLSHNNITDESANKIHSIVSNHSNIQTVRLFGNRINDRKQFIKDKRFEIW", "length": 2813, "header": "tr|E7FBQ2-1|E7FBQ2_DANRE Isoform 1 of Uncharacterized protein si:ch211-281l24.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-281l24.3 PE=4 SV=1 CANONICAL=E7FBQ2-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 1254, "start_aa": "Thr", "end_pos": 1254, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr1254", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:798456", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798456", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7FBQ2", "url": "https://www.uniprot.org/uniprotkb/E7FBQ2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1100, "end_pos": 1102, "annotation": "n_glycosylation_sequon" }, { "start_pos": 113, "end_pos": 115, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1197, "end_pos": 1199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1403, "end_pos": 1405, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1563, "end_pos": 1565, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1604, "end_pos": 1606, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1630, "end_pos": 1632, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1822, "end_pos": 1824, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1959, "end_pos": 1961, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2123, "end_pos": 2125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2143, "end_pos": 2145, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2221, "end_pos": 2223, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2295, "end_pos": 2297, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2354, "end_pos": 2356, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2627, "end_pos": 2629, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2769, "end_pos": 2771, "annotation": "n_glycosylation_sequon" }, { "start_pos": 2784, "end_pos": 2786, "annotation": "n_glycosylation_sequon" }, { "start_pos": 797, "end_pos": 799, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FBQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FBQ2" }, { "id": "PS50853", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50853" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Fibronectin type-III", "eco_id": "ECO_0000259", "start_pos": 1155, "end_pos": 1252, "start_aa": "Asn", "end_aa": "Ala", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7FBQ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FBQ2" }, { "id": "PS50089", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50089" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "RING-type", "eco_id": "ECO_0000259", "start_pos": 500, "end_pos": 540, "start_aa": "Cys", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 1254 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1100, "end_pos": 1102 }, { "start_pos": 113, "end_pos": 115 }, { "start_pos": 1197, "end_pos": 1199 }, { "start_pos": 1403, "end_pos": 1405 }, { "start_pos": 1563, "end_pos": 1565 }, { "start_pos": 1604, "end_pos": 1606 }, { "start_pos": 1630, "end_pos": 1632 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 1822, "end_pos": 1824 }, { "start_pos": 1959, "end_pos": 1961 }, { "start_pos": 2123, "end_pos": 2125 }, { "start_pos": 2143, "end_pos": 2145 }, { "start_pos": 2221, "end_pos": 2223 }, { "start_pos": 2295, "end_pos": 2297 }, { "start_pos": 2354, "end_pos": 2356 }, { "start_pos": 2627, "end_pos": 2629 }, { "start_pos": 2769, "end_pos": 2771 }, { "start_pos": 2784, "end_pos": 2786 }, { "start_pos": 797, "end_pos": 799 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FGQ0-1", "uniprot_ac": "E7FGQ0", "uniprot_id": "E7FGQ0_DANRE", "mass": { "chemical_mass": 43815.0, "monoisotopic_mass": 43815.0 }, "refseq": { "ac": "XP_689652", "name": "tyrosine-protein kinase STYK1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689652" }, "gene_names": [ { "name": "si:ch73-206d17.1", "type": "recommended", "evidence": [ { "id": "E7FGQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0" } ] }, { "name": "si:ch73-206d17.1", "type": "synonym", "evidence": [ { "id": "XP_689652", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689652" } ] } ], "protein_names": [ { "name": "Tyrosine-protein kinase STYK1 isoform X1", "type": "synonym", "evidence": [ { "id": "E7FGQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0/entry#names_and_taxonomy" } ] }, { "name": "tyrosine-protein kinase STYK1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_689652", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689652" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_689652.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_689652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689652" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FGQ0", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch73-206d17.1", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-143", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-143", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000086159", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000086159", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "561155", "url": "https://www.ncbi.nlm.nih.gov/gene/561155", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000719", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000719", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001245", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001245", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR008266", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008266", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011009", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011009", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050122", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050122", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561155", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561155", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PERIMML", "url": "https://omabrowser.org/oma/group/PERIMML/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7FGQ0", "url": "https://www.orthodb.org/?gene=E7FGQ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24416", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24416:SF631", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24416:SF631", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07714", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07714", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-8863795", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8863795", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_689652", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_689652", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TE59", "url": "https://www.uniprot.org/uniprotkb/A0AB32TE59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TE59-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TE59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FGQ0", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FGQ0-1", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-143", "url": "https://zfin.org/ZDB-GENE-090313-143", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAVQAQCNISSGSDPACYDEGSGPLAVIIIPSLLALSTLIVVSQIIWSFVTKRSSAQKITSSSSNVNEREHVQLDAGIGSLRPANVLGPLELPVQCTLEGVEVLQMGRYGPICMGQLKQDNTSTAVMIKTLKDRSTQSESAEFMDLVLFHAAVSKHENIVKLLFCQTRRTPMYLLLEASVPGNLLNFLWSLREDRCGESSVFSEKSVFLVAKQIAAGLDYLHSHHRVIHGDVAARNMLIGSAFSVKVSGLDFAFESRQKKKVDREQEANVPVKWQAPERMMRLPLTDRSDVWSFGILLYEMITLGSPPYPDLDPSEVLPRTLAHYRMKRPENCGAPLFDLIKYCCMWNFKDRPVYSAIIRLLDSYSYFADTKPLCSEVQIDVSEYKKKAGLPS", "length": 393, "header": "tr|E7FGQ0-1|E7FGQ0_DANRE Isoform 1 of Tyrosine-protein kinase STYK1 isoform X1 OS=Danio rerio OX=7955 GN=si:ch73-206d17.1 PE=4 SV=1 CANONICAL=E7FGQ0-1" }, "isoforms": [ { "isoform_ac": "A0AB32TE59-1", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0/entry#A0AB32TE59-1", "sequence": { "sequence": "MAVQAQCNISSGSDPACYDEGSGPLAVIIIPSLLALSTLIVVSQIIWSFVTKRSSAQKITSSSSNVNEREHVQLDAGIGSLRPANVLGPLELPVQCTLEGVEVLQMGRYGPICMDRSTQSESAEFMDLVLFHAAVSKHENIVKLLFCQTRRTPMYLLLEASVPGNLLNFLWSLREDRCGESSVFSEKSVFLVAKQIAAGLDYLHSHHRVIHGDVAARNMLIGSAFSVKVSGLDFAFESRQKKKVDREQEANVPVKWQAPERMMRLPLTDRSDVWSFGILLYEMITLGSPPYPDLDPSEVLPRTLAHYRMKRPENCGAPLFDLIKYCCMWNFKDRPVYSAIIRLLDSYSYFADTKPLCSEVQIDVSEYKKKAGLPS", "length": 375, "header": "tr|A0AB32TE59-1|E7FGQ0_DANRE Computationally mapped isoform of Tyrosine-protein kinase STYK1 isoform X1 OS=Danio rerio OX=7955 GN=si:ch73-206d17.1 PE=4 SV=1 CANONICAL=E7FGQ0-1" }, "locus": {} }, { "isoform_ac": "E7FGQ0-1", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0/entry#E7FGQ0-1", "sequence": { "sequence": "MAVQAQCNISSGSDPACYDEGSGPLAVIIIPSLLALSTLIVVSQIIWSFVTKRSSAQKITSSSSNVNEREHVQLDAGIGSLRPANVLGPLELPVQCTLEGVEVLQMGRYGPICMGQLKQDNTSTAVMIKTLKDRSTQSESAEFMDLVLFHAAVSKHENIVKLLFCQTRRTPMYLLLEASVPGNLLNFLWSLREDRCGESSVFSEKSVFLVAKQIAAGLDYLHSHHRVIHGDVAARNMLIGSAFSVKVSGLDFAFESRQKKKVDREQEANVPVKWQAPERMMRLPLTDRSDVWSFGILLYEMITLGSPPYPDLDPSEVLPRTLAHYRMKRPENCGAPLFDLIKYCCMWNFKDRPVYSAIIRLLDSYSYFADTKPLCSEVQIDVSEYKKKAGLPS", "length": 393, "header": "tr|E7FGQ0-1|E7FGQ0_DANRE Isoform 1 of Tyrosine-protein kinase STYK1 isoform X1 OS=Danio rerio OX=7955 GN=si:ch73-206d17.1 PE=4 SV=1 CANONICAL=E7FGQ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561155", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561155", "resource": "KEGG Pathway" }, { "id": "R-DRE-8863795", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8863795", "resource": "Reactome", "description": "Downregulation of ERBB2 signaling" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "protein kinase activity", "id": "GO:0004672", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004672", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ0", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0" } ], "pmid": "" }, { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ0", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0" } ], "pmid": "" }, { "name": "non-membrane spanning protein tyrosine kinase activity", "id": "GO:0004715", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004715", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ0", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endomembrane system", "id": "GO:0012505", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0012505", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ0", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7FGQ0", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FGQ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FGQ0" }, { "id": "PS50011", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50011" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Protein kinase", "eco_id": "ECO_0000259", "start_pos": 98, "end_pos": 368, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F083-1", "uniprot_ac": "E7F083", "uniprot_id": "E7F083_DANRE", "mass": { "chemical_mass": 91682.0, "monoisotopic_mass": 91682.0 }, "refseq": { "ac": "XP_688618", "name": "armadillo repeat-containing protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688618" }, "gene_names": [ { "name": "armc3", "type": "recommended", "evidence": [ { "id": "E7F083", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F083" } ] }, { "name": "armc3", "type": "synonym", "evidence": [ { "id": "XP_688618", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688618" } ] } ], "protein_names": [ { "name": "Armadillo repeat-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F083", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F083/entry#names_and_taxonomy" } ] }, { "name": "armadillo repeat-containing protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_688618", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688618" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_688618.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_688618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688618" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F083", "url": "https://www.uniprot.org/uniprotkb/E7F083" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "armc3", "url": "https://www.uniprot.org/uniprotkb/E7F083", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110614-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110614-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000074708", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000074708", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "560136", "url": "https://www.ncbi.nlm.nih.gov/gene/560136", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011989", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011989", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052441", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052441", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055164", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055164", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058678", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058678", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:560136", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560136", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LYPMQSR", "url": "https://omabrowser.org/oma/group/LYPMQSR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F083", "url": "https://www.orthodb.org/?gene=E7F083", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46618", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46618", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46618:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46618:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00514", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00514", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF14381", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14381", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25598", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25598", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_688618", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688618", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TEX2", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEX2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TEX2-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TEX2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TIX8", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIX8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TIX8-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIX8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR64", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IR64-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IR64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F083", "url": "https://www.uniprot.org/uniprotkb/E7F083", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F083-1", "url": "https://www.uniprot.org/uniprotkb/E7F083-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110614-1", "url": "https://zfin.org/ZDB-GENE-110614-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGKKVKKEAETCPKDVFDPLSIESKTATTAVLMLSSPEEEVLAKACEAIHKFAEKGDENKTCLMCLGAIEPLSLLISHEDKIVRRNAVMALGVMASNNEVKKHLKCLDVIPAIISKLSPEENVMVHEFATLCLASLSVDFSYKIQIFESNGLEPLIQLLSSPDPDVKKNSVECIFNLVQDVQNRAAVQRLNGLPPLLDLLRSEFSVIQQLALHTIEKITTDTETCVAFRNVQGFERILEVVAMKEFSDLHEGALRVILNCLEDTESMQLFQTMGGLEQLLQCVGTSTVAEVKANAVKAIAKMAQSSENRKILHERNIEKTLTDLLTQENESVRTAVCQAVATVSKNLSSRDTFRSLDGIRPIVQLLNSEGSELRMAAAEALSSLTNSNNLNAYAIYDAEGDRLLVRQLQDSCTGAAVYAAMALTNMASQEELRKSILAHEAMPALVELLHSTDNNILISAVQAVASLTCDAEARQELRNVGGLSALVQLLKSINAEIRRNASWAISVCANDEITASELCNVGALEILQEISLSSHRSNKFSQLALQKLLDSNLSLKYSLTGHLSSSDITTDGFYDPGQIRVGHQFPVLEDISKQVVNQHRATIAVNGKPQNQFIPKGPEEGKQDSPTDTTASSVLNGRRSSKTPSKTKGKGHKEEDEKKKEEDECKPHQKIMVEETWSLPYDAAFHNLVKEAAESIMPLKDEVKMYTALAMLVCDAMGGQVEQQKLHDFLWELHISELKFEACSNIVLIGKIKKGTYFHRALLFKVLADRIGLSCSLIRGEYNRAWNEILIMGPKKAYGYSQPESYIIDLMHQPGNLMKSNSQAALIYQSI", "length": 831, "header": "tr|E7F083-1|E7F083_DANRE Isoform 1 of Armadillo repeat-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=armc3 PE=1 SV=2 CANONICAL=E7F083-1" }, "isoforms": [ { "isoform_ac": "A0AB32TEX2-1", "url": "https://www.uniprot.org/uniprotkb/E7F083/entry#A0AB32TEX2-1", "sequence": { "sequence": "MGKKVKKEAETCPKDVFDPLSIESKTATTAVLMLSSPEEEVLAKACEAIHKFAEKGDENKTCLMCLGAIEPLSLLISHEDKIVRRNAVMALGVMASNNEVKKHLKCLDVIPAIISKLSPEENVMVHEFATLCLASLSVDFSYKIQIFESNGLEPLIQLLSSPDPDVKKNSVECIFNLVQDVQNRAAVQRLNGLPPLLDLLRSEFSVIQQLALHTIEKITTDTETCVAFRNVQGFERILEVVAMKEFSDLHEGALRVILNCLEDTESMQLFQTMGGLEQLLQCVGTSTVAEVKANAVKAIAKMAQSSENRKILHERNIEKTLTDLLTQENESVRTAVCQAVATVSKNLSSRDTFRSLDGIRPIVQLLNSEGSELRMAAAEALSSLTNSNNLNAYAIYDAEGDRLLVRQLQDSCTGAAVYAAMALTNMASQEELRKSILAHEAMPALVELLHSTDNNILISAVQAVASLTCDAEARQELRNVGGLSALVQLLKSINAEIRRNASWAISVCANDEITASELCNVGALEILQEISLSSHRSNKFSQLALQKLLDSNLSLKYSLTGHLSSSDITTDGFYDPGQIRVGHQFPVLEDISKQVVNQHRATIAVNGKPQNQFIPKGPEEGKQDSPTDTTASSVLNGRRSSKTPSKTKGKGHKEEDEKKKEEDECKPHQKIMVEETWSLPYDAAFHNLVKEAAESIMPLKDEVKMYTALAMFLLTELG", "length": 718, "header": "tr|A0AB32TEX2-1|E7F083_DANRE Computationally mapped isoform of Armadillo repeat-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=armc3 PE=1 SV=1 CANONICAL=E7F083-1" }, "locus": {} }, { "isoform_ac": "A0AB32TIX8-1", "url": "https://www.uniprot.org/uniprotkb/E7F083/entry#A0AB32TIX8-1", "sequence": { "sequence": "MCLGAIEPLSLLISHEDKIVRRNAVMALGVMASNNEVKKHLKCLDVIPAIISKLSPEENVMVHEFATLCLASLSVDFSYKIQIFESNGLEPLIQLLSSPDPDVKKNSVECIFNLVQDVQNRAAVQRLNGLPPLLDLLRSEFSVIQQLALHTIEKITTDTETCVAFRNVQGFERILEVVAMKEFSDLHEGALRVILNCLEDTESMQLFQTMGGLEQLLQCVGTSTVAEVKANAVKAIAKMAQSSENRKILHERNIEKTLTDLLTQENESVRTAVCQAVATVSKNLSSRDTFRSLDGIRPIVQLLNSEGSELRMAAAEALSSLTNSNNLNAYAIYDAEGDRLLVRQLQDSCTGAAVYAAMALTNMASQEELRKSILAHEAMPALVELLHSTDNNILISAVQAVASLTCDAEARQELRNVGGLSALVQLLKSINAEIRRNASWAISVCANDEITASELCNVGALEILQEISLSSHRSNKFSQLALQKLLDSNLSLKYSLTGHLSSSDITTDGFYDPGQIRVGHQFPVLEDISKQVVNQHRATIAVNGKPQNQFIPKGPEEGKQDSPTDTTASSVLNGRRSSKTPSKTKGKGHKEEDEKKKEEDECKPHQKIMVEETWSLPYDAAFHNLVKEAAESIMPLKDEVKMYTALAMLVCDAMGGQVEQQKLHDFLWELHISELKFEACSNIVLIGKIKKGTYFHRALLFKVLADRIGLSCSLIRGEYNRAWNEILIMGPKKAYGYSQPESYIIDLMHQPGNLMKSNSQAALIYQSI", "length": 768, "header": "tr|A0AB32TIX8-1|E7F083_DANRE Computationally mapped isoform of Armadillo repeat-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=armc3 PE=1 SV=1 CANONICAL=E7F083-1" }, "locus": {} }, { "isoform_ac": "A0AC58IR64-1", "url": "https://www.uniprot.org/uniprotkb/E7F083/entry#A0AC58IR64-1", "sequence": { "sequence": "MCLGAIEPLSLLISHEDKIVRRNAVMALGVMASNNEVKKHLKCLDVIPAIISKLSPEENVMVHEFATLCLASLSVDFSYKIQIFESNGLEPLIQLLSSPDPDVKKNSVECIFNLVQDVQNRAAVQRLNGLPPLLDLLRSEFSVIQQLALHTIEKITTDTETCVAFRNVQGFERILEVVAMKEFSDLHEGALRVILNCLEDTESMQLFQTMGGLEQLLQCVGTSTVAEVKANAVKAIAKMAQSSENRKILHERNIEKTLTDLLTQENESVRTAVCQAVATVSKNLSSRDTFRSLDGIRPIVQLLNSEGSELRMAAAEALSSLTNSNNLNAYAIYDAEGDRLLVRQLQDSCTGAAVYAAMALTNMASQEELRKSILAHEAMPALVELLHSTDNNILISAVQAVASLTCDAEARQELRNVGGLSALVQLLKSINAEIRRNASWAISVCANDEITASELCNVGALEILQEISLSSHRSNKFSQLALQKLLDSNLSLKYSLTGHLSSSDITTDGFYDPGQIRVGHQFPVLEDISKQVVNQHRATIAVNGKPQNQFIPKGPEEGKQDSPTDTTASSVLNGRRSSKTPSKTKGKGHKEEDEKKKEEDECKPHQKIMVEETWSLPYDAAFHNLVKEAAESIMPLKDEVKMYTALAMFLLTELG", "length": 655, "header": "tr|A0AC58IR64-1|A0AC58IR64_DANRE Computationally mapped isoform of Armadillo repeat-containing protein 3 isoform X4 OS=Danio rerio OX=7955 GN=armc3 PE=1 SV=1 CANONICAL=E7F083-1" }, "locus": {} }, { "isoform_ac": "E7F083-1", "url": "https://www.uniprot.org/uniprotkb/E7F083/entry#E7F083-1", "sequence": { "sequence": "MGKKVKKEAETCPKDVFDPLSIESKTATTAVLMLSSPEEEVLAKACEAIHKFAEKGDENKTCLMCLGAIEPLSLLISHEDKIVRRNAVMALGVMASNNEVKKHLKCLDVIPAIISKLSPEENVMVHEFATLCLASLSVDFSYKIQIFESNGLEPLIQLLSSPDPDVKKNSVECIFNLVQDVQNRAAVQRLNGLPPLLDLLRSEFSVIQQLALHTIEKITTDTETCVAFRNVQGFERILEVVAMKEFSDLHEGALRVILNCLEDTESMQLFQTMGGLEQLLQCVGTSTVAEVKANAVKAIAKMAQSSENRKILHERNIEKTLTDLLTQENESVRTAVCQAVATVSKNLSSRDTFRSLDGIRPIVQLLNSEGSELRMAAAEALSSLTNSNNLNAYAIYDAEGDRLLVRQLQDSCTGAAVYAAMALTNMASQEELRKSILAHEAMPALVELLHSTDNNILISAVQAVASLTCDAEARQELRNVGGLSALVQLLKSINAEIRRNASWAISVCANDEITASELCNVGALEILQEISLSSHRSNKFSQLALQKLLDSNLSLKYSLTGHLSSSDITTDGFYDPGQIRVGHQFPVLEDISKQVVNQHRATIAVNGKPQNQFIPKGPEEGKQDSPTDTTASSVLNGRRSSKTPSKTKGKGHKEEDEKKKEEDECKPHQKIMVEETWSLPYDAAFHNLVKEAAESIMPLKDEVKMYTALAMLVCDAMGGQVEQQKLHDFLWELHISELKFEACSNIVLIGKIKKGTYFHRALLFKVLADRIGLSCSLIRGEYNRAWNEILIMGPKKAYGYSQPESYIIDLMHQPGNLMKSNSQAALIYQSI", "length": 831, "header": "tr|E7F083-1|E7F083_DANRE Isoform 1 of Armadillo repeat-containing protein 3 isoform X1 OS=Danio rerio OX=7955 GN=armc3 PE=1 SV=2 CANONICAL=E7F083-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:560136", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560136", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XNH0-1", "protein_name": "Armadillo repeat containing 3", "gene_name": "ARMC3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MGKKVKKEVEPPPKDVFEPLLIESKAAATVVLMLDSPEEEVLAKACDAIYKFASKGDENKVALLGLGAVERLYKLISHEDPIVRRNAIMVFGIMASNHDVKKLLRELDVTSSLLSHLVPEEDVIIHEFATLCLAHMAVEYTTKVQIFEQGGLEPLISLLGSPDPDVTKNSVECIYLLVQEFQSRAAVCELNVIPPLLDLLKSEYPVIQLLALKTLEVISKDREMRIILGENEGLDCLLKILETNEFNDLHVEALAVLGNCLEDVHTMQLIRQTGGLKKLLSFVGVSTVPDIQKNAAKAIAKAASDSENRKILNEEGVENCLINLLEIDDDGVKVAASQAISAMCENLASKRAFGLQGIPQLVQLLSSDDEEVKEAAVIALANLTTASPSNASAVAEAEGIEPLVKSLNAERHGAVANAATVLTNMAMQEPLRLSIQSHGVMSVLTEPLRSSSSQVQSRAALTVAAFGCDANARSELRNAGGLGPLVELLHSKDKEVRRNACWAVMVCASDELTAVELCRLGALDILEEINLSTGRRNNFSEAALERLLDNNLSQKYSQMGYLSSSNVITDGFYDYGKIKPGVKLLSLEELSMQELTDRRAIIFINAKPQEDVLAMEEKPQHISSEQTTLSVPTSRKSSREKVRKGKGKKEEEKIKEVVEIMSEVQDEINLEDVQWQPPPDFMLMNYINDASKIILPLTTTREQVVALAQFVADKMGGAIERDKLHDFSWELHISEIEFELKSNIVPIGKVKKGTFYHRALLFKVIADRLGIGCSLVRGEYNRAWNEVKLVDDSPQGVTGLLLPPQEYIVDLMFVPGFLMKQESVEADQYKHI", "length": 832 }, "evidence": [ { "id": "E7F083", "url": "https://omabrowser.org/oma/group/E7F083/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7GWH5-1", "protein_name": "Armadillo repeat-containing protein 3 isoform X1", "gene_name": "Armc3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MGKKIKKEVEPPPKDVFDPLTIESKKAATVVLMLNSPEEEILAKACEAIYKFALKGEENKATLLELGAVEPLTKLLTHEDKIVRRNATMIFGILASNSDVKKLLRELEVMNSVIAQLAPEEEVVIHEFASLCLANLSVEYTGKVQIYEHGGLEPLIRLLSSPDPDVKKNSIECIYNLVQDFQCRTTLHELNPIPPILELLKSEYPIIQLLALKTLGVITCDKESRAMLKENQGLDQLSKILETKEWNDLHVEALAVIANCLEDMDTVVLMQQTGILRKLLSFAENSTVPDIQKNSAKAITKAAYDAENRKIFHEQEVEKCLVALLGSDSDGTKIAASQAISAMSENSSSKDFFNTQGIPQIVQLLRSDNEEVREAAALALANLTTSSSANANAAAEADAIDPLINILSSKRDGAIANAATVLTNMAIQEPLRSIIQGHDVMQALLAPLHSTNTVVQSTAALTVASTACDVEARNQLRNCGGLEPLVELLHSKNDEVRRHASWAVMVCASDEVTAVELCKLGALDILGEINLSVSRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNLISDGFYDCGRINPGTKLLPLKELSLQEVNDQRAILLVNCKSDISPPPSMEDKSSDVGYGRSISSSSSLRRASREKTKEKSFHFSAGFGSPTEEKSEPTSGRNTALSRGAAKEKGSRKGRGKKEEEKVKEEEEILAVPKLTEGSSEKEWYPPPDPELCVYVYEVTKSILPIVNIKDQIEALAKFVADKMGGKIPKEKMSDFSWELHISELKFQLKSNVIPIGHIKKGIFYHRALLFKVLADKIGVGSCLVRGEYSRAWNEVKLLNEARKGIIGRLPPPEEYIVDLMFHPGALLKLRSKEADLYRFL", "length": 872 }, "evidence": [ { "id": "E7F083", "url": "https://omabrowser.org/oma/group/E7F083/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0ABK0LJ64-1", "protein_name": "Armadillo repeat containing 3", "gene_name": "Armc3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGKKIKKEVEPPPKDVFDPLTIESKKAATVVLMLKSPEEDILAKACEAIYKFALKGEENKATLLELGAVEPLTKLLTHEDKIVRRNAMMIFGILASNSDVKKLLRELEVMSSVIAQLSPEEEVVIHEFASLCLANMSVEYTGKVQIFEHGGLEPLIRLLSSPDPDVKKNSIECIYNLVQDFQCRTTLQELNAIPPILELLKSEYPIIQLLALKTLGVITCDKEARTTLKDNQGLDHLTKILETKELNDLHVEALAVIANCLEDMDTMVLMQQSGSLKKVLSFAENSTIPDIQKNAAKAITKAAYDPENRKVFHEQEVEKCLVTLLGSDSDGTKIAASQAISAMCENLSCKEFFNTQGIPQIVQLLKSDNEEVREAAALALANLTTSSPANANAAAEADAIDPLINILSSKRDGAVANAATVLTNMAIQEPLRAIIQNHEIMRALLGPLHSTNTVVQSTAALTVAATACDVESRNELKNCGGLEPLIELLHSKNDEVRRHASWAIMVCAGDELMAVELCRLGALDILEEINRSLSRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNIISDGFYDYGRINPGTKLLPLKELCLQELNDQRAILLVNNKSDISPPPSMEDKSSDVGYGRSISSSSSLRRASKEKANFRFSAGFGSPTEEKSEPASGRNTVLSRGATKEKGARKGKGKKEEEKVKEEEEVLAVPKLTESPEKEWYPPPDPEFCLYVLEVIKTILPIVNIKEQIEVLAKFVADKMGGKIAKEKLADFSWELHISELKFQLKSNVIPIGYIKKGIFYHRALLFKALADKIGVGCSLVRGEYSRGWNEVKLVNEARKGIIGNLPPPDEYIVDLMFHPGTLLKLRSKEADLYRFL", "length": 868 }, "evidence": [ { "id": "HGNC:30964", "url": "https://alliancegenome.org/gene/HGNC:30964#orthology", "database": "AGR" }, { "id": "MGI:1918132", "url": "https://alliancegenome.org/gene/MGI:1918132#orthology", "database": "AGR" }, { "id": "E7F083", "url": "https://omabrowser.org/oma/group/E7F083/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2AU72-1", "protein_name": "Armadillo repeat-containing protein 3", "gene_name": "Armc3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGKKIKKEVEPPPKDVFDPITIESKKAATVVLMLKSPEEDILAKACEAIYKFALKGEENKATLLELGAVEPLTKLLTHEDKTVRRNAMMIFGILASNSDVKKLLRELEVMNSVIAQLSPEEEVVIHEFASLCLANMSVEYTGKVQIFEHGGLEPLIRLLSSSDPDVKKNSIECIYNLVQDFQCRTTLQELNAIPPILELLRSEYPIIQLLALKTLGVITCDKEARTMLKENQGLDHLTKILETKELNDLHVEALSVIANCLEDMDTMVLMQQTGSLKKVLSFAESSTIPDIQKNAAKAIAKAAYDPENRKVFHEQEVEKCLVTLLGSDSDGTKIAASQAISALCENLSCKEFFNTQGIPQIVQLLRSDNEEVREAAALALANLTTSSPANANAAAEADAIDPLINILSSKRDGAIANAATVLTNMATQEPLRAIIQNHEIMHALLGPLHSTNTLVQSTAALTVAATACDVEARTQLRNCGGLVPLVGLLHSKNDEVRRHASWAVMVCAGDEPMAVELCRLGALNILEEINRSLSRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNIISDGFYDYGRINPGTKLLSLKELCLQELNDQRAILLVNNKSDTSPPPSMEDKSSDVGYGRSISSSSSLRRGSKEKANAIFGSPTEEKSEPASVRNTILSRAFTKEKGVSKKKSRLQLICSSYLLWKGKGKKEEEKVKEEEEILALPKFTEGSPEKEWNPPPDPEFCVYVLEVTKSILPIVNLKEQIEVLAKYVADKMGGKIPKEKLADFSWELHISELKFQLKSNVVPIGYIKKGIFYHRALLFKALADKIGVGCSLVRGEYSRGWNEVKLVNEARKGMIGNLPPPEEYIVDLMFHPGNLLKLRSKEADLYRFL", "length": 881 }, "evidence": [ { "id": "HGNC:30964", "url": "https://alliancegenome.org/gene/HGNC:30964#orthology", "database": "AGR" }, { "id": "MGI:1918132", "url": "https://alliancegenome.org/gene/MGI:1918132#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110614-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110614-1#orthology", "database": "AGR" }, { "id": "E7F083", "url": "https://omabrowser.org/oma/group/E7F083/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P39968-1", "protein_name": "Vacuolar protein 8", "gene_name": "VAC8", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MGSCCSCLKDSSDEASVSPIADNEREAVTLLLGYLEDKDQLDFYSGGPLKALTTLVYSDNLNLQRSAALAFAEITEKYVRQVSREVLEPILILLQSQDPQIQVAACAALGNLAVNNENKLLIVEMGGLEPLINQMMGDNVEVQCNAVGCITNLATRDDNKHKIATSGALIPLTKLAKSKHIRVQRNATGALLNMTHSEENRKELVNAGAVPVLVSLLSSTDPDVQYYCTTALSNIAVDEANRKKLAQTEPRLVSKLVSLMDSPSSRVKCQATLALRNLASDTSYQLEIVRAGGLPHLVKLIQSDSIPLVLASVACIRNISIHPLNEGLIVDAGFLKPLVRLLDYKDSEEIQCHAVSTLRNLAASSEKNRKEFFESGAVEKCKELALDSPVSVQSEISACFAILALADVSKLDLLEANILDALIPMTFSQNQEVSGNAAAALANLCSRVNNYTKIIEAWDRPNEGIRGFLIRFLKSDYATFEHIALWTILQLLESHNDKVEDLVKNDDDIINGVRKMADVTFERLQRSGIDVKNPGSNNNPSSNDNNSNNNDTGSEHQPVEDASLELYNITQQILQFLH", "length": 578 }, "evidence": [ { "id": "HGNC:30964", "url": "https://alliancegenome.org/gene/HGNC:30964#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5W041-2", "protein_name": "Armadillo repeat-containing protein 3", "gene_name": "ARMC3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGKKIKKEVEPPPKDVFDPLMIESKKAATVVLMLNSPEEEILAKACEAIYKFALKGEENKTTLLELGAVEPLTKLLTHEDKIVRRNATMIFGILASNNDVKKLLRELDVMNSVIAQLAPEEEVVIHEFASLCLANMSAEYTSKVQIFEHGGLEPLIRLLSSPDPDVKKNSMECIYNLVQDFQCRAKLQELNAIPPILDLLKSEYPVIQLLALKTLGVIANDKESRTMLRDNQGLDHLIKILETKELNDLHIEALAVIANCLEDMDTMVQIQQTGGLKKLLSFAENSTIPDIQKNAAKAITKAAYDPENRKLFHEQEVEKCLVALLGSENDGTKIAASQAISAMCENSGSKDFFNNQGIPQLIQLLKSDNEEVREAAALALANLTTCNPANANAAAEADGIDPLINLLSSKRDGAIANAATVLTNMAMQEPLRLNIQNHDIMHAIISPLRSANTVVQSKAALAVTATACDVEARTELRNSGGLEPLVELLRSKNDEVRKHASWAVMVCAGDELTANELCRLGALDILEEVNVSGTRKNKFSEAAYNKLLNNNLSLKYSQTGYLSSSNIINDGFYDYGRINPGTKLLPLKELCLQEPSDLRAVLLINSKSYVSPPSSMEDKSDVGYGRSISSSSSLRRSSKEKNKKNSYHFSAGFGSPIEDKSEPASGRNTVLSKSATKEKGWRKSKGKKEEEKVKEEEEVMVVPKFVGEGSSDKEWCPPSDPDFSMYVYEVTKSILPITNIKEQIEDLAKYVAEKMGGKIPKEKLPDFSWELHISELKFQLKSNVIPIGHVKKGIFYHRALLFKALADRIGIGCSLVRGEYGRAWNEVMLQNDSRKGVIGGLPAPEMYVIDLMFHPGGLMKLRSREADLYRFI", "length": 872 }, "evidence": [ { "id": "HGNC:30964", "url": "https://alliancegenome.org/gene/HGNC:30964#orthology", "database": "AGR" }, { "id": "MGI:1918132", "url": "https://alliancegenome.org/gene/MGI:1918132#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110614-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110614-1#orthology", "database": "AGR" }, { "id": "E7F083", "url": "https://omabrowser.org/oma/group/E7F083/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "animal organ development", "id": "GO:0048513", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048513", "evidence": [ { "database": "UniProtKB", "id": "E7F083", "url": "https://www.uniprot.org/uniprotkb/E7F083" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 329, "end_pos": 331, "annotation": "n_glycosylation_sequon" }, { "start_pos": 346, "end_pos": 348, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 552, "end_pos": 554, "annotation": "n_glycosylation_sequon" }, { "start_pos": 59, "end_pos": 61, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F083", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F083" }, { "id": "PF14381", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14381" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "EDR1/CTR1/ARMC3-like peptidase-like", "eco_id": "ECO_0000259", "start_pos": 681, "end_pos": 818, "start_aa": "Tyr", "end_aa": "Met", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7F083", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F083" }, { "id": "PF25598", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25598" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U-box", "eco_id": "ECO_0000259", "start_pos": 290, "end_pos": 524, "start_aa": "Glu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 329, "end_pos": 331 }, { "start_pos": 346, "end_pos": 348 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 552, "end_pos": 554 }, { "start_pos": 59, "end_pos": 61 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EZM2-1", "uniprot_ac": "E7EZM2", "uniprot_id": "E7EZM2_DANRE", "mass": { "chemical_mass": 110297.0, "monoisotopic_mass": 110297.0 }, "refseq": { "ac": "NP_001314720", "name": "centrosomal protein of 112 kDa", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314720" }, "gene_names": [ { "name": "cep112", "type": "recommended", "evidence": [ { "id": "E7EZM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZM2" } ] }, { "name": "cep112", "type": "synonym", "evidence": [ { "id": "NP_001314720", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314720" } ] }, { "name": "si:ch211-196b14.3", "type": "synonym", "evidence": [ { "id": "NP_001314720", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314720" }, { "id": "E7EZM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZM2" } ] }, { "name": "zgc:165627", "type": "synonym", "evidence": [ { "id": "NP_001314720", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314720" }, { "id": "E7EZM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZM2" } ] } ], "protein_names": [ { "name": "Centrosomal protein of 112 kDa", "type": "synonym", "evidence": [ { "id": "E7EZM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZM2/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein of 112 kDa", "type": "synonym", "evidence": [ { "id": "NP_001314720", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314720" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588718.22746956.1, GFIL01045982.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1. On May 25, 2016 this sequence version replaced XP_009298080.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001314720", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314720" } ] } ], "disease": [ { "disease_id": "DOID:0112109", "recommended_name": { "id": "DOID:0112109", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112109", "name": "spermatogenic failure 44", "description": "A spermatogenic failure characterized by high prevalence of acephalic sperm and reduced progressive motility of sperm that has_material_basis_in homozygous or compound heterozygous mutation in the CEP112 gene on chromosome 17q24.1." }, "synonyms": [ { "id": "DOID:0112109", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112109", "name": "SPGF44", "description": "" }, { "id": "MONDO:0033622", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033622", "name": "spermatogenic failure 44", "description": "" }, { "id": "MONDO:0033622", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0033622", "name": "SPGF44", "description": "" }, { "id": "MIM:619044", "resource": "MIM", "url": "https://www.omim.org/entry/619044", "name": "Spermatogenic failure 44", "description": "Spermatogenic failure 44" } ], "unlinked_id_list": [], "evidence": [ { "id": "0112109", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0112109" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZM2", "url": "https://www.uniprot.org/uniprotkb/E7EZM2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cep112", "url": "https://www.uniprot.org/uniprotkb/E7EZM2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120104-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120104-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000079679", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000079679", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "571489", "url": "https://www.ncbi.nlm.nih.gov/gene/571489", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027831", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027831", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055310", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055310", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:571489", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571489", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMHEKEX", "url": "https://omabrowser.org/oma/group/RMHEKEX/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EZM2", "url": "https://www.orthodb.org/?gene=E7EZM2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18871", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18871", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18871:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18871:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14846", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14846", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001314720", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314720", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TFJ1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TFJ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TFJ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TFJ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYR4", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYR4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYR4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYR4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYR8", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYR8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYR8-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYR8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYT0", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYT0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYT0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYT0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYU4", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYU4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYU5", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYU5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYU5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYU5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYU7", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYU7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYU7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYU7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZM2", "url": "https://www.uniprot.org/uniprotkb/E7EZM2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZM2-1", "url": "https://www.uniprot.org/uniprotkb/E7EZM2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120104-2", "url": "https://zfin.org/ZDB-GENE-120104-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSANWSNMSDEDYFVILDSEFDHYLVDMKPFVLKLPHKTERQRCALWIKKLCDPVSCGSGLTGRKNRNLYARLLLHMLRKGVLEGPFNHKPDTGSLKTLPTYMSIYFDEPLTRSQDQRSAAMPDWVSGELEPTESTWSNSPISNTHRKQNLFSNTSPSRPLSSSPIKHTLKDDVKMAEAHRRPTISSDDSDFEARFNSWNLGIENPRYLRENPIPLSPIYKSTLGKSSTVLSEATPAKADKEVELRTKVLEAKHQEDTLRMQQKHDAEIQKILDRKNGEIDELKSLYRGKQKEAEETVRRLEKRVQSLLRESQVIRQTKEKQISELKKMSDQSAESLKNEWEKKLHAAVAHMEQEKSELQKKHTENIQELLEDTNQRLAKMEAEYSGQMQATEHIVRELETRVKQLSVEVESGNLLRQKVTQEKAELELQIASISAELQEANQRSTTLQKEMDQMRVHYEEALQKLQARHNADMSHFQQEHAVSAAKASEVIQDLEQTVIHLKQQIQEAESRRHRQLRDQENKWQQEITDMQNSTEKKLQTLQAELEKERADRKRKISKMEDSLRDKEEQLVRVRDSQRHQAQQAESALENFKKQVELSSEKTYADMKQQMEKVEADLIRSKSLREKQCKEFRHQLEELQQKYEQQIVELKLQHEQERTHLLQTHNAEKDSLVQDHQREIDSLDKQTRAAMVQQQTQTQEWRKRDAQTISDLEAQVHSLRKEVLAAHSQRKQQLMELGVLREEERQRSAQDHQAALDRLRAEMEQVRQDLEKTHKAERELAQEKTSSRIKHLEKEYQQKMAKSAQVISELQASLSSVKEDSRQTQQSLERKLQAAQSYWDEEKTQLNRDADQSNKILHERVETLQRQLNAVEKKLMNRELEYQEQITHVRQECELKIKGLMPAELQQELEDTITSLKSQVSFLQKRASVLQEQLDAGHIRR", "length": 942, "header": "tr|E7EZM2-1|E7EZM2_DANRE Isoform 1 of Centrosomal protein of 112 kDa OS=Danio rerio OX=7955 GN=cep112 PE=1 SV=2 CANONICAL=E7EZM2-1" }, "isoforms": [ { "isoform_ac": "A0AB32TFJ1-1", "url": "https://www.uniprot.org/uniprotkb/E7EZM2/entry#A0AB32TFJ1-1", "sequence": { "sequence": "MSSANWSNMSDEDYFVILDSEFDHYLVDMKPFVLKLPHKTERQRCALWIKKLCDPVSCGSGLTGRKNRNLYARLLLHMLRKGVLEGPFNHKPDTGSLKTLPTYMSIYFDEPLTRSQDQRSAAMPDWVSGELEPTESTWSNSPISNTHRKQNLFSNTSPSRPLSSSPIKHTLKDDVKMAEAHRRPTISSDDSDFEARFNSWNLGIENPRYLRENPIPLSPIYKSTLGKSSTVLSEATPAKADKEVELRTKVLEAKHQEDTLRMQQKHDAEIQKILDRKNGEIDELKSLYRGKQKEAEETVRRLEKRVQSLLRESQVIRQTKEKQISELKKMSDQSAESLKNEWEKKLHAAVAHMEQEKSELQKKHTENIQELLEDTNQRLAKMEAEYSGQMQATEHIVRELETRVKQLSVEVESGNLLRQKVTQEKAELELQIASISAELQEANQRSTTLQKEMDQMRVHYEEALQKLQARHNADMSHFQQEHAVSAAKASEVIQDLEQTVIHLKQQIQEAESRRHRQLRDQENKWQQEITDMQNSTEKKLQTLQAELEKERADRKRKISKMEDSLRDKEEQLVRVRDSQRHQAQQAESALENFKKQVELSSEKTYADMKQQMEKVEADLIRSKSLREKQCKEFRHQLEELQQKYEQQIVELKLQHEQERTHLLQTHNAEKDSLVQDHQREIDSLDKQTRAAMVQQQTQTQEWRKRDAQTISDLEAQVHSLRKEVLAAHSQRKQQLMELGVLREEERQRSAQDHQAALDRLRAEMEQVRQDLEKTHKAERELAQEKVISELQASLSSVKEDSRQTQQSLERKLQAAQSYWDEEKTQLNRDADQSNKILHERVETLQRQLNAVEKKLMNRELEYQEQITHVRQECELKIKGLMPAELQQELEDTITSLKSQVSFLQKRASVLQEQLDAGHIRR", "length": 921, "header": "tr|A0AB32TFJ1-1|E7EZM2_DANRE Computationally mapped isoform of Centrosomal protein of 112 kDa OS=Danio rerio OX=7955 GN=cep112 PE=1 SV=1 CANONICAL=E7EZM2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYR4-1", "url": "https://www.uniprot.org/uniprotkb/E7EZM2/entry#A0AC58IYR4-1", "sequence": { "sequence": "MSSANWSNMSDEDYFVILDSEFDHYLVDMKPFVLKLPHKTERQRCALWIKKLCDPVSCGSGLTGRKNRNLYARLLLHMLRKGVLEGPFNHKPDTGSLKTLPTYMSIYFDEPLTRSQDQRSAAMPDWVSGELEPTESTWSNSPISNTHRKQNLFSNTSPSRPLSSSPIKHTLKDDVKMAEAHRRPTISSDDSDFEARFNSWNLGIENPRYLRENPIPLSPIYKSTLGKSSTVLSEATPAKADKEVELRTKVLEAKHQEDTLRMQQKHDAEIQKILDRKNGEIDELKSLYRGKQKEAEETVRRLEKRVQSLLRESQVIRQTKEKQISELKKMSDQSAESLKNEWEKKLHAAVAHMEQEKSELQKKHTENIQELLEDTNQRLAKMEAEYSGQMQATEHIVRELETRVKQLSVEVESGNLLRQKVTQEKAELELQIASISAELQEANQRSTTLQKEMDQMRVHYEEALQKLQARHNADMSHFQQEHAVSAAKASEVIQDLEQTVIHLKQQIQEAESRRHRQLRDQENKWQQEITDMQNSTEKKLQTLQAELEKERADRKRKISKMEDSLRDKEEQLVRVRDSQRHQAQQAESALENFKKQVELSSEKTYADMKQQIVELKLQHEQERTHLLQTHNAEKDSLVQDHQREIDSLDKQTRAAMVQQQTQTQEWRKRDAQTISDLEAQVHSLRKEVLAAHSQRKQQLMELGVLREEERQRSAQDHQAALDRLRAEMEQVRQDLEKTHKAERELAQEKVISELQASLSSVKEDSRQTQQSLERKLQAAQSYWDEEKTQLNRDADQSNKILHERVETLQRQLNAVEKKLMNRELEYQEQITHVRQECELKIKGLMPAELQQELEDTITSLKSQVSFLQKRASVLQEQLDAGHIRR", "length": 885, "header": "tr|A0AC58IYR4-1|A0AC58IYR4_DANRE Computationally mapped isoform of Centrosomal protein of 112 kDa isoform X3 OS=Danio rerio OX=7955 GN=cep112 PE=1 SV=1 CANONICAL=E7EZM2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYR8-1", "url": "https://www.uniprot.org/uniprotkb/E7EZM2/entry#A0AC58IYR8-1", "sequence": { "sequence": "MSSANWSNMSDEDYFVILDSEFDHYLVDMKPFVLKLPHKTERQRCALWIKKLCDPVSCGSGLTGRKNRNLYARLLLHMLRKGVLEGPFNHKPDTGSLKTLPTYMSIYFDEPLTRSQDQRSAAMPDWVSGELEPTESTWSNSPISNTHRKQNLFSNTSPSRPLSSSPIKHTLKDDVKMAEAHRRPTISSDDSDFEARFNSWNLGIENPRYLRENPIPLSPIYKSTLGKSSTVLSEATPAKADKEVELRTKVLEAKHQEDTLRMQQKHDAEIQKILDRKNGEIDELKSLYRGKQKEAEETVRRLEKRVQSLLRESQVIRQTKEKQISELKKMSDQSAESLKNEWEKKLHAAVAHMEQEKSELQKKHTENIQELLEDTNQRLAKMEAEYSGQMQATEHIVRELETRVKQLSVEVESGNLLRQKVTQEKAELELQIASISAELQEANQRSTTLQKEMDQMRVHYEEALQKLQARHNADMSHFQQEHAVSAAKASEVIQDLEQTVIHLKQQIQEAESRRHRQLRDQENKWQQEITDMQNSTEKKLQTLQAELEKERADRKRKISKMEDSLRDKEEQLVRVRDSQRHQAQQAESALENFKKQVELSSEKTYADMKQQIVELKLQHEQERTHLLQTHNAEKDSLVQDHQREIDSLDKQTRAAMVQQQTQTQEWRKRDAQTISDLEAQVHSLRKEVLAAHSQRKQQLMELGVLREEERQRSAQDHQAALDRLRAEMEQVRQDLEKTHKAERELAQEKTSSRIKHLEKEYQQKMAKSAQVISELQASLSSVKEDSRQTQQSLERKLQAAQSYWDEEKTQLNRDADQSNKILHERVETLQRQLNAVEKKLMNRELEYQEQITHVRQECELKIKGLMPAELQQELEDTITSLKSQVSFLQKRASVLQEQLDAGHIRR", "length": 906, "header": "tr|A0AC58IYR8-1|A0AC58IYR8_DANRE Computationally mapped isoform of Centrosomal protein of 112 kDa isoform X2 OS=Danio rerio OX=7955 GN=cep112 PE=1 SV=1 CANONICAL=E7EZM2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYT0-1", "url": "https://www.uniprot.org/uniprotkb/E7EZM2/entry#A0AC58IYT0-1", "sequence": { "sequence": "MSSANWSNMSDEDYFVILDSEFDHYLVDMKPFVLKLPHKTERQRCALWIKKLCDPVSCGSGLTGRKNRNLYARLLLHMLRKGVLEGPFNHKPDTGSLKTLPTYMSIYFDEPLTRSQDQRSAAMPDWVSGELEPTESTWSNSPISNTHRKQNLFSNTSPSRPLSSSPIKHTLKDDVKMAEAHRRPTISSDDSDFEARFNSWNLGIENPRYLRENPIPLSPIYKSTLGKSSTVLSEATPAKADKEVELRTKVLEAKHQEDTLRMQQKHDAEIQKILDRKNGEIDELKSLYRGKQKEAEETVRRLEKRVQSLLRESQVIRQTKEKQISELKKMSDQSAESLKNEWEKKLHAAVAHMEQEKSELQKKHTENIQELLEDTNQRLAKMEAEYSGQMQATEHIVRELETRVKQLSVEVESGNLLRQKVTQEKAELELQIASISAELQEANQRSTTLQKEMDQMRVHYEEALQKLQARHNADMSHFQQEHAVSAAKASEVIQDLEQTVIHLKQQIQEAESRRHRQLRDQENKWQQEITDMQNSTEKKLQTLQAELEKERADRKRKISKMEDSLRDKEEQLVRVRDSQRHQAQQAESALENFKKQVELSSEKTYADMKQQMEKVEADLIRSKSLREKQCKEFRHQLEELQQKYEQQIVELKLQHEQERTHLLQTHNAEKDSLVQDHQREIDSLDKQTRAAMVQQQTQTQEWRKRDAQTSSRIKHLEKEYQQKMAKSAQVISELQASLSSVKEDSRQTQQSLERKLQAAQSYWDEEKTQLNRDADQSNKILHERVETLQRQLNAVEKKLMNRELEYQEQITHVRQECELKIKGLMPAELQQELEDTITSLKSQVSFLQKRASVLQEQLDAGHIRR", "length": 865, "header": "tr|A0AC58IYT0-1|A0AC58IYT0_DANRE Computationally mapped isoform of Centrosomal protein of 112 kDa isoform X4 OS=Danio rerio OX=7955 GN=cep112 PE=1 SV=1 CANONICAL=E7EZM2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYU4-1", "url": "https://www.uniprot.org/uniprotkb/E7EZM2/entry#A0AC58IYU4-1", "sequence": { "sequence": "MSSANWSNMSDEDYFVILDSEFDHYLVDMKPFVLKLPHKTERQRCALWIKKLCDPVSCGSGLTGRKNRNLYARLLLHMLRKGVLEGPFNHKPDTGSLKTLPTYMSIYFDEPLTRSQDQRSAAMPDWVSGELEPTESTWSNSPISNTHRKQNLFSNTSPSRPLSSSPIKHTLKDDVKMAEAHRRPTISSDDSDFEARFNSWNLGIENPRYLRENPIPLSPIYKSTLGKSSTVLSEATPAKADKEVELRTKVLEAKHQEDTLRMQQKHDAEIQKILDRKNGEIDELKSLYRGKQKEAEETVRRLEKRVQSLLRESQVIRQTKEKQISELKKMSDQSAESLKNEWEKKLHAAVAHMEQEKSELQKKHTENIQELLEDTNQRLAKMEAEYSGQMQATEHIVRELETRVKQLSVEVESGNLLRQKVTQEKAELELQIASISAELQEANQRSTTLQKEMDQMRVHYEEALQKLQARHNADMSHFQQEHAVSAAKASEVIQDLEQTVIHLKQQIQEAESRRHRQLRDQENKWQQEITDMQNSTEKKLQTLQAELEKERADRKRKISKMEDSLRDKEEQLVRVRDSQRHQAQQAESALENFKKQVELSSEKTYADMKQQIVELKLQHEQERTHLLQTHNAEKDSLVQDHQREIDSLDKQTRAAMVQQQTQTQEWRKRDAQALF", "length": 675, "header": "tr|A0AC58IYU4-1|A0AC58IYU4_DANRE Computationally mapped isoform of Centrosomal protein of 112 kDa isoform X7 OS=Danio rerio OX=7955 GN=cep112 PE=1 SV=1 CANONICAL=E7EZM2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYU5-1", "url": "https://www.uniprot.org/uniprotkb/E7EZM2/entry#A0AC58IYU5-1", "sequence": { "sequence": "MSSANWSNMSDEDYFVILDSEFDHYLVDMKPFVLKLPHKTERQRCALWIKKLCDPVSCGSGLTGRKNRNLYARLLLHMLRKGVLEGPFNHKPDTGSLKTLPTYMSIYFDEPLTRSQDQRSAAMPDWVSGELEPTESTWSNSPISNTHRKQNLFSNTSPSRPLSSSPIKHTLKDDVKMAEAHRRPTISSDDSDFEARFNSWNLGIENPRYLRENPIPLSPIYKSTLGKSSTVLSEATPAKADKEVELRTKVLEAKHQEDTLRMQQKHDAEIQKILDRKNGEIDELKSLYRGKQKEAEETVRRLEKRVQSLLRESQVIRQTKEKQISELKKMSDQSAESLKNEWEKKLHAAVAHMEQEKSELQKKHTENIQELLEDTNQRLAKMEAEYSGQMQATEHIVRELETRVKQLSVEVESGNLLRQKVTQEKAELELQIASISAELQEANQRSTTLQKEMDQMRVHYEEALQKLQARHNADMSHFQQEHAVSAAKASEVIQDLEQTVIHLKQQIQEAESRRHRQLRDQENKWQQEITDMQNSTEKKLQTLQAELEKERADRKRKISKMEDSLRDKEEQLVRVRDSQRHQAQQAESALENFKKQVELSSEKTYADMKQQIVELKLQHEQERTHLLQTHNAEKDSLVQDHQREIDSLDKQTRAAMVQQQTQTQEWRKRDAQTSSRIKHLEKEYQQKMAKSAQVISELQASLSSVKEDSRQTQQSLERKLQAAQSYWDEEKTQLNRDADQSNKILHERVETLQRQLNAVEKKLMNRELEYQEQITHVRQECELKIKGLMPAELQQELEDTITSLKSQVSFLQKRASVLQEQLDAGHIRR", "length": 829, "header": "tr|A0AC58IYU5-1|A0AC58IYU5_DANRE Computationally mapped isoform of Centrosomal protein of 112 kDa isoform X5 OS=Danio rerio OX=7955 GN=cep112 PE=1 SV=1 CANONICAL=E7EZM2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYU7-1", "url": "https://www.uniprot.org/uniprotkb/E7EZM2/entry#A0AC58IYU7-1", "sequence": { "sequence": "MSSANWSNMSDEDYFVILDSEFDHYLVDMKPFVLKLPHKTERQRCALWIKKLCDPVSCGSGLTGRKNRNLYARLLLHMLRKGVLEGPFNHKPDTGSLKTLPTYMSIYFDEPLTRSQDQRSAAMPDWVSGELEPTESTWSNSPISNTHRKQNLFSNTSPSRPLSSSPIKHTLKDDVKMAEAHRRPTISSDDSDFEARFNSWNLGIENPRYLRENPIPLSPIYKSTLGKSSTVLSEATPAKADKEVELRTKVLEAKHQEDTLRMQQKHDAEIQKILDRKNGEIDELKSLYRGKQKEAEETVRRLEKRVQSLLRESQVIRQTKEKQISELKKMSDQSAESLKNEWEKKLHAAVAHMEQEKSELQKKHTENIQELLEDTNQRLAKMEAEYSGQMQATEHIVRELETRVKQLSVEVESGNLLRQKVTQEKAELELQIASISAELQEANQRSTTLQKEMDQMRVHYEEALQKLQARHNADMSHFQQEHAVSAAKASEVIQDLEQTVIHLKQQIQEAESRRHRQLRDQENKWQQEITDMQNSTEKKLQTLQAELEKERADRKRKISKMEDSLRDKEEQLVRVRDSQRHQAQQAESALENFKKQVELSSEKTYADMKQQMEKVEADLIRSKSLREKQCKEFRHQLEELQQKYEQQIVELKLQHEQERTHLLQTHNAEKDSLVQDHQREIDSLDKQTRAAMVQQQTQTQEWRKRDAQALF", "length": 711, "header": "tr|A0AC58IYU7-1|A0AC58IYU7_DANRE Computationally mapped isoform of Centrosomal protein of 112 kDa isoform X6 OS=Danio rerio OX=7955 GN=cep112 PE=1 SV=1 CANONICAL=E7EZM2-1" }, "locus": {} }, { "isoform_ac": "E7EZM2-1", "url": "https://www.uniprot.org/uniprotkb/E7EZM2/entry#E7EZM2-1", "sequence": { "sequence": "MSSANWSNMSDEDYFVILDSEFDHYLVDMKPFVLKLPHKTERQRCALWIKKLCDPVSCGSGLTGRKNRNLYARLLLHMLRKGVLEGPFNHKPDTGSLKTLPTYMSIYFDEPLTRSQDQRSAAMPDWVSGELEPTESTWSNSPISNTHRKQNLFSNTSPSRPLSSSPIKHTLKDDVKMAEAHRRPTISSDDSDFEARFNSWNLGIENPRYLRENPIPLSPIYKSTLGKSSTVLSEATPAKADKEVELRTKVLEAKHQEDTLRMQQKHDAEIQKILDRKNGEIDELKSLYRGKQKEAEETVRRLEKRVQSLLRESQVIRQTKEKQISELKKMSDQSAESLKNEWEKKLHAAVAHMEQEKSELQKKHTENIQELLEDTNQRLAKMEAEYSGQMQATEHIVRELETRVKQLSVEVESGNLLRQKVTQEKAELELQIASISAELQEANQRSTTLQKEMDQMRVHYEEALQKLQARHNADMSHFQQEHAVSAAKASEVIQDLEQTVIHLKQQIQEAESRRHRQLRDQENKWQQEITDMQNSTEKKLQTLQAELEKERADRKRKISKMEDSLRDKEEQLVRVRDSQRHQAQQAESALENFKKQVELSSEKTYADMKQQMEKVEADLIRSKSLREKQCKEFRHQLEELQQKYEQQIVELKLQHEQERTHLLQTHNAEKDSLVQDHQREIDSLDKQTRAAMVQQQTQTQEWRKRDAQTISDLEAQVHSLRKEVLAAHSQRKQQLMELGVLREEERQRSAQDHQAALDRLRAEMEQVRQDLEKTHKAERELAQEKTSSRIKHLEKEYQQKMAKSAQVISELQASLSSVKEDSRQTQQSLERKLQAAQSYWDEEKTQLNRDADQSNKILHERVETLQRQLNAVEKKLMNRELEYQEQITHVRQECELKIKGLMPAELQQELEDTITSLKSQVSFLQKRASVLQEQLDAGHIRR", "length": 942, "header": "tr|E7EZM2-1|E7EZM2_DANRE Isoform 1 of Centrosomal protein of 112 kDa OS=Danio rerio OX=7955 GN=cep112 PE=1 SV=2 CANONICAL=E7EZM2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain.", "journal": "PLoS ONE", "date": "2008", "authors": "Sreenivasan Rajini, Cai Minnie, Bartfai Richard, Wang Xingang, Christoffels Alan, Orban Laszlo", "evidence": [ { "database": "UniProtKB", "id": "E7EZM2", "url": "https://www.uniprot.org/uniprotkb/E7EZM2" } ], "reference": [ { "type": "PubMed", "id": "18335061", "url": "https://glygen.org/publication/PubMed/18335061" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7EZM2", "url": "https://www.uniprot.org/uniprotkb/E7EZM2" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "E7EZM2", "url": "https://www.uniprot.org/uniprotkb/E7EZM2" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "The splicing factor DHX38 enables retinal development through safeguarding genome integrity.", "journal": "IScience", "date": "2023", "authors": "Sun Kui, Han Yunqiao, Li Jingzhen, Yu Shanshan, Huang Yuwen, Zhang Yangjun, Reilly Jamas, Tu Jiayi, Gao Pan, Jia Danna, Chen Xiang, Hu Hualei, Ren Mengmeng, Li Pei, Luo Jiong, Ren Xiang, Zhang Xianqin, Shu Xinhua, Liu Fei, Liu Mugen, Tang Zhaohui", "evidence": [ { "database": "UniProtKB", "id": "E7EZM2", "url": "https://www.uniprot.org/uniprotkb/E7EZM2" } ], "reference": [ { "type": "PubMed", "id": "37867960", "url": "https://glygen.org/publication/PubMed/37867960" } ] } ], "pathway": [ { "id": "dre:571489", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571489", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ABV2-1", "protein_name": "Centrosomal protein 112", "gene_name": "Cep112", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPAAARGGGTGKLDSSAPGLLDGPQGFETVRLWRRGVGGRVDRLLVVAPDRSMEMGSEEEKWEKLDAEFDHFVVDMKPFVLKLPHRSERQRCALWIRKLCEPSGTGAGLMGRKNRNLYAKLLLHMLRRGVLEGPFTHRPEPGTLKVLPSYMRACTFHINHPSRKSPSGLPWASIKSIYFDEPNSAQSKDSSPEKLPDWVMGELEPGERRLSDSWQLSCGEENALLLSASDAHREQYTGKLRMRSHSVSPTDREDRQHITSKICEVHPKKSPISLDDSDIEVRLNSWNLGIENPRYLRQKPLPVSLMTPKVSLRNSSNLHDDHFLSRMHEKELDMKTKMMEAKFSEEKLKLQKKHDAEVQKILERKNNELEELKILYKKKQTETEETVRKLEKKVQILIRDCQVIRETKENQITELKKICEQSTESLNNDWEKKLHSAVAEMEKEKFELQKHHTETIQELLEDTNVRLSKMEGDYMVQTQSTNHMIKDLEGRVQQLMGEAENSNLQRQKLTQEKLELERCYQITCSELQELKTRQNLLHTEKEHLVNDYEQNVKLLKTKYDSDINILRQEHALSTSKTSVVIEELEQNIRQLKQQVQESELQRKQQVKDQEDKFHMEKNHLKYIYEEKVHELKSELDKEKEDAQRKIHKFEEALKEKEEQLGRVTEVQRLQAQQADAALEEFKRQVEVTSEKVYSDMKEQMEKVEADLSRSKSLREKQSKEFLWQLEDARQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREVENLENQLRAANMEHENQIQESKKRDAQVIADMEAQVHKLREELINVNSHRKQQLVELGLLREEEKQRAARDHETAVKKLKAESERVKMELKKTHAAETEMTLEKANSRLKQIEKEYTQKLAKSSQIIAELQTTISSLKEESSRQQLAAERRLQDVIQKFEDEKQQLIRDNDQAIKALQDELETRSNQVRSAEKKLQHKELEAQEQMMYIRQEYETKFKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTTYQSRR", "length": 1030 }, "evidence": [ { "id": "MGI:1923673", "url": "https://alliancegenome.org/gene/MGI:1923673#orthology", "database": "AGR" }, { "id": "HGNC:28514", "url": "https://alliancegenome.org/gene/HGNC:28514#orthology", "database": "AGR" }, { "id": "E7EZM2", "url": "https://omabrowser.org/oma/group/E7EZM2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5PR68-1", "protein_name": "Centrosomal protein of 112 kDa", "gene_name": "Cep112", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "METGSEEEKWEKLDAEFDHFVVDMKPFVLKLPHRSERQRCALWIRKLCEPSGTGAGLMGRKNRNLYAKLLLHMLRRGILEGPFTHRPEPGTLKTLPSYMSIYFDEPNQAQPKDSSPEKLPDWVRGELQTGEQRLSDSWQCSSGEDNTLVLAASDAHREQYTGKLRMRSHSVSPTYREDKQHITSKICEVHSKTSPISLDDSDIEVRLNSWNLGIENPRYLRQKPLPVSLMTPKGSLRKASSLHDDHFLSRMHEKELDMKTKMMEAKFSEEKLKLQQKHDAEVQKILERKNNELEELKILYKKKQTETEETIRKLEKKVQILIRDCQVIRETKENQITELKKICEQSTESLNNDWEKKLHNAVAEMEKDKFELQKHHTETIQELLEDTNVRLSKMEADYVVQMQSTNHMIKELEGRVQQLMGEAENSNLQRQKLTQEKLELERCYQITCNELQELKTRRNILHKEKEHLVNDYEQNVKLLKTKYDSDINLLRQEHALSTSKTSGVIEELEQNICQLKQQVQESELQRKQQVKDQENKFHMEKNHLKHTYEKKVHELQSELDKEKEDAQRKIHKFEEALKEKEEQLSRVTEVQRLQAQQADAALEEFKRQVEVNSEKVYGEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDAKQRYEQQIVELKLEHEQEKTHLLQQHSAEKDSLVRDHDREIENLEKQLRAANMEHENQIQESKKRDAQVIADMEAQVHKLREELISVNSQRKQQLIELGLLREEEKQRAAKDHETAVKKLKAESERVKMELKKTHAAETEMTLEKANSRLKQIEKEYTQKLAKSSQIIAELQTTISSLKEESSRQQLAAERRLQDVIQKFEDEKQQLIRDNDQAIKALQDELETRSHQVRSAEKKLHHKELEAQEQIMYIRQEYETKFKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTTYQSRR", "length": 954 }, "evidence": [ { "id": "MGI:1923673", "url": "https://alliancegenome.org/gene/MGI:1923673#orthology", "database": "AGR" }, { "id": "HGNC:28514", "url": "https://alliancegenome.org/gene/HGNC:28514#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120104-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120104-2#orthology", "database": "AGR" }, { "id": "E7EZM2", "url": "https://omabrowser.org/oma/group/E7EZM2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N8E3-1", "protein_name": "Centrosomal protein of 112 kDa", "gene_name": "CEP112", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEVGSEEEKWEKLDAEFDHFVVDMKPFVLKLPHRTERQRCALWIRKLCEPSGTGAGIMGRKNRNLYAKLLLHMLKRGALEGPFTHRPEPGTLKILPSYMSIYFDEPNPARAKGSSPEGLPAWVLGELETSEHKLNESWKLSSGEDNTLVQSPTDVYSREQYTGKLRVRSHSLSPTHREDGQNITPKICEVYSKKSPVSLDDSDIEARLNSWNLGIENPRYLRQKPIPVSLMTPKFSLRKSSSFHDDHFLSRIREKELDMKTKMMEAKFHEEKLKLQQKHDADVQKILERKNNEIEELKTLYRSKQHETEETIRKLEKKVQTLIRDCQVIRETKEDQIAELKKICEQSTESLNNDWEKKLHNAVAEMEQEKFDLQKQHTENIQELLEDTNVRLNKMESEYMAQTQSTNHMIKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADINLLKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEKKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQVELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRDHEREIENLEKQLRAANMEHENQIQEFKKRDAQVIADMEAQVHKLREELINVNSQRKQQLVELGLLREEEKQRATREHEIVVNKLKAESEKMKIELKKTHAAETEMTLEKANSKLKQIEKEYTQKLAKSSQIIAELQTTISSLKEENSQQQLAAERRLQDVRQKFEDEKKQLIRDNDQAIKVLQDELENRSNQVRCAEKKLQHKELESQEQITYIRQEYETKLKGLMPASLRQELEDTISSLKSQVNFLQKRASILQEELTTYQGRR", "length": 955 }, "evidence": [ { "id": "MGI:1923673", "url": "https://alliancegenome.org/gene/MGI:1923673#orthology", "database": "AGR" }, { "id": "HGNC:28514", "url": "https://alliancegenome.org/gene/HGNC:28514#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120104-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120104-2#orthology", "database": "AGR" }, { "id": "E7EZM2", "url": "https://omabrowser.org/oma/group/E7EZM2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 155, "end_pos": 157, "annotation": "n_glycosylation_sequon" }, { "start_pos": 534, "end_pos": 536, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EZM2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZM2" }, { "id": "PF14846", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14846" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUF4485", "eco_id": "ECO_0000259", "start_pos": 18, "end_pos": 103, "start_aa": "Leu", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 155, "end_pos": 157 }, { "start_pos": 534, "end_pos": 536 }, { "start_pos": 5, "end_pos": 7 }, { "start_pos": 8, "end_pos": 10 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F5X2-1", "uniprot_ac": "E7F5X2", "uniprot_id": "E7F5X2_DANRE", "mass": { "chemical_mass": 64737.0, "monoisotopic_mass": 64737.0 }, "refseq": { "ac": "XP_002667001", "name": "copine-8 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667001" }, "gene_names": [ { "name": "cpne8", "type": "recommended", "evidence": [ { "id": "E7F5X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5X2" } ] }, { "name": "cpne8", "type": "synonym", "evidence": [ { "id": "XP_002667001", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667001" } ] } ], "protein_names": [ { "name": "Copine-8", "type": "recommended", "evidence": [ { "id": "E7F5X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5X2/entry#names_and_taxonomy" } ] }, { "name": "Copine VIII", "type": "synonym", "evidence": [ { "id": "E7F5X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5X2/entry#names_and_taxonomy" } ] }, { "name": "copine-8 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002667001", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667001" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_002667001", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667001" } ] }, { "annotation": "Probable calcium-dependent phospholipid-binding protein that may play a role in calcium-mediated intracellular processes.", "evidence": [ { "database": "UniProtKB", "id": "A0AB32TIB6", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIB6#function" }, { "database": "UniProtKB", "id": "ARBA00057254", "url": "https://www.uniprot.org/uniprotkb/ARBA00057254#function" }, { "database": "UniProtKB", "id": "E7F5X2", "url": "https://www.uniprot.org/uniprotkb/E7F5X2#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F5X2", "url": "https://www.uniprot.org/uniprotkb/E7F5X2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cpne8", "url": "https://www.uniprot.org/uniprotkb/E7F5X2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100809-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100809-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000025189", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000025189", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01459", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01459", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04047", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04047", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd04048", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd04048", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100332028", "url": "https://www.ncbi.nlm.nih.gov/gene/100332028", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000008", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000008", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002035", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002035", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR010734", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010734", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035892", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035892", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036465", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036465", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037768", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037768", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100332028", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100332028", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QCANVPI", "url": "https://omabrowser.org/oma/group/QCANVPI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F5X2", "url": "https://www.orthodb.org/?gene=E7F5X2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10857:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10857:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00168", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00168", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07002", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07002", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-9013148", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013148", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9013406", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013406", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002667001", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002667001", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TIB6", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIB6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TIB6-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TIB6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IZ60", "url": "https://www.uniprot.org/uniprotkb/A0AC58IZ60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IZ60-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IZ60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F5X2", "url": "https://www.uniprot.org/uniprotkb/E7F5X2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F5X2-1", "url": "https://www.uniprot.org/uniprotkb/E7F5X2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100809-1", "url": "https://zfin.org/ZDB-GENE-100809-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSTLTGGFLNMASLADFEPLAAVIPATKVEITVSCRNLLDRDTFSKSDPICVLYTQTVANREWREFGRTEVIDNTLNPDFVHKFILDYFFEERQNLRFDLYDLDSKSENLSKHDFLGQMYCTLGEVVGSPGSRMERSLIGIPGKNCGTVIVKAEELGNCRESVLMQFCGNKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLDPVWQAFKIPVRALCNGDYDRAIKIEVYDWDRDGGHDYIGEFSTSYRELSKGHTQFTVWEVLNPKKKKKKKKYLNSGTVTLLSCFIDVEVTFLDYIKGGTQINFTVAIDFTASNGNPSQPTSLHYMSPYHLNAYALALRAVGEIIQDYDSDKLFPALGFGAKLPPDGRVSHEFPLNGNPDNPYCSGIEGVLEAYYQSLKSVRLYGPTYFSPVINHVARYASLVKDGSEYFILLIISDGVISDMAQTKESIVNASSLPMSIIIVGVGPAEFDEMIELDGDEVRISSRGRFAERDIVQFVPFRDYIDRRGNHILSMARLAKDVLAEIPDQFLQYVRSRGIKPQHSAHSTISKPPASLVHPIHHLQTQI", "length": 575, "header": "tr|E7F5X2-1|E7F5X2_DANRE Isoform 1 of Copine-8 OS=Danio rerio OX=7955 GN=cpne8 PE=3 SV=1 CANONICAL=E7F5X2-1" }, "isoforms": [ { "isoform_ac": "A0AB32TIB6-1", "url": "https://www.uniprot.org/uniprotkb/E7F5X2/entry#A0AB32TIB6-1", "sequence": { "sequence": "MSTLTGGFLNMASLADFEPLAAVIPATKVEITVSCRNLLDRDTFSKSDPICVLYTQTVANREWREFGRTEVIDNTLNPDFVHKFILDYFFEERQNLRFDLYDLDSKSENLSKHDFLGQMYCTLGEVVGSPGSRMERSLIGIPGKNCGTVIVKAEELGNCRESVLMQFCGNKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLDPVWQAFKIPVRALCNGDYDRAIKIEVYDWDRDGGHDYIGEFSTSYRELSKGHTQFTVWEVLNPKKKKKKKKYLNSGTTSYRRSCIMSS", "length": 298, "header": "tr|A0AB32TIB6-1|E7F5X2_DANRE Computationally mapped isoform of Copine-8 OS=Danio rerio OX=7955 GN=cpne8 PE=3 SV=1 CANONICAL=E7F5X2-1" }, "locus": {} }, { "isoform_ac": "A0AC58IZ60-1", "url": "https://www.uniprot.org/uniprotkb/E7F5X2/entry#A0AC58IZ60-1", "sequence": { "sequence": "MYCTLGEVVGSPGSRMERSLIGIPGKNCGTVIVKAEELGNCRESVLMQFCGNKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLDPVWQAFKIPVRALCNGDYDRAIKIEVYDWDRDGGHDYIGEFSTSYRELSKGHTQFTVWEVLNPKKKKKKKKYLNSGTVTLLSCFIDVEVTFLDYIKGGTQINFTVAIDFTASNGNPSQPTSLHYMSPYHLNAYALALRAVGEIIQDYDSDKLFPALGFGAKLPPDGRVSHEFPLNGNPDNPYCSGIEGVLEAYYQSLKSVRLYGPTYFSPVINHVARYASLVKDGSEYFILLIISDGVISDMAQTKESIVNASSLPMSIIIVGVGPAEFDEMIELDGDEVRISSRGRFAERDIVQFVPFRDYIDRRGNHILSMARLAKDVLAEIPDQFLQYVRSRGIKPQHSAHSTISKPPASLVHPIHHLQTQI", "length": 457, "header": "tr|A0AC58IZ60-1|A0AC58IZ60_DANRE Computationally mapped isoform of Copine-8 isoform X2 OS=Danio rerio OX=7955 GN=cpne8 PE=3 SV=1 CANONICAL=E7F5X2-1" }, "locus": {} }, { "isoform_ac": "E7F5X2-1", "url": "https://www.uniprot.org/uniprotkb/E7F5X2/entry#E7F5X2-1", "sequence": { "sequence": "MSTLTGGFLNMASLADFEPLAAVIPATKVEITVSCRNLLDRDTFSKSDPICVLYTQTVANREWREFGRTEVIDNTLNPDFVHKFILDYFFEERQNLRFDLYDLDSKSENLSKHDFLGQMYCTLGEVVGSPGSRMERSLIGIPGKNCGTVIVKAEELGNCRESVLMQFCGNKLDKKDFFGKSDPFLVFYRSNEDGTFTICHKTEVVKNTLDPVWQAFKIPVRALCNGDYDRAIKIEVYDWDRDGGHDYIGEFSTSYRELSKGHTQFTVWEVLNPKKKKKKKKYLNSGTVTLLSCFIDVEVTFLDYIKGGTQINFTVAIDFTASNGNPSQPTSLHYMSPYHLNAYALALRAVGEIIQDYDSDKLFPALGFGAKLPPDGRVSHEFPLNGNPDNPYCSGIEGVLEAYYQSLKSVRLYGPTYFSPVINHVARYASLVKDGSEYFILLIISDGVISDMAQTKESIVNASSLPMSIIIVGVGPAEFDEMIELDGDEVRISSRGRFAERDIVQFVPFRDYIDRRGNHILSMARLAKDVLAEIPDQFLQYVRSRGIKPQHSAHSTISKPPASLVHPIHHLQTQI", "length": 575, "header": "tr|E7F5X2-1|E7F5X2_DANRE Isoform 1 of Copine-8 OS=Danio rerio OX=7955 GN=cpne8 PE=3 SV=1 CANONICAL=E7F5X2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100332028", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100332028", "resource": "KEGG Pathway" }, { "id": "R-DRE-9013148", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013148", "resource": "Reactome", "description": "CDC42 GTPase cycle" }, { "id": "R-DRE-9013406", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9013406", "resource": "Reactome", "description": "RHOQ GTPase cycle" } ], "orthologs": [ { "uniprot_canonical_ac": "B5DEX3-1", "protein_name": "Copine-8", "gene_name": "Cpne8", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWARDKCSAPPLEMDSRYTSATGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYTQAVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGRKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI", "length": 577 }, "evidence": [ { "id": "MGI:1914121", "url": "https://alliancegenome.org/gene/MGI:1914121#orthology", "database": "AGR" }, { "id": "HGNC:23498", "url": "https://alliancegenome.org/gene/HGNC:23498#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q1ZXB3-1", "protein_name": "Copine-F", "gene_name": "cpnF", "tax_id": 44689, "organism": "Dictyostelium discoideum", "sequence": { "sequence": "MAETIRPISKIELRFKLADIKKPSSQIIVYCNSGDSKRFDLIGATERIDNKSEPFFNTTINIDYYFESVQKLYLLAINHNLKTLDFTKIDQLDVVGEFTPTIGDLISRDGKRLIGDIKDKDKITGKIEITAEEIYETGHNIILQLKGTKLDKKDLFSSDPYFKIYKSSPSGNSIVFESSVIKNNINPIFDPIVIRLQELNGGCMFRELTFEFWDHNDIVDDELIGSFRTNTDEILSGIIKEFPIINQKLKSKKSNYEHSGIINFIDSRILYKPTIQDFINGNGNGNGNGDGNCLIDLMVAIDCTESNGDQKLETSLHYNVKPHQNQYIRSLLALESQLLNNFGVKLEKRVEVFGFGAVINKHPNHNFRFHYIIDDRPNTLKAGISGVIELYDKAIPKIQFTSPTKISSIIEDATRYSLQDFHSTQLKYSILLILIDSDITDYESTVDEIVEASKAPLSIIFIGVGEYSFQNIPQLDGEKNGNIRLIGRFDRKQIRDNVHFISFKEFSINQIDFQNEILRKLPNQLTEFMEFKNYLPNGLSYTQTEIKKIK", "length": 550 }, "evidence": [ { "id": "E7F5X2", "url": "https://omabrowser.org/oma/group/E7F5X2/", "database": "OMA" } ], "glygen_name": "Cellular slime mold", "common_name": "Social amoeba" }, { "uniprot_canonical_ac": "Q86YQ8-1", "protein_name": "Copine-8", "gene_name": "CPNE8", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSRYNSTAGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYVQGVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGKKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELSRGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI", "length": 564 }, "evidence": [ { "id": "MGI:1914121", "url": "https://alliancegenome.org/gene/MGI:1914121#orthology", "database": "AGR" }, { "id": "HGNC:23498", "url": "https://alliancegenome.org/gene/HGNC:23498#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100809-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100809-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DC53-1", "protein_name": "Copine-8", "gene_name": "Cpne8", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWARDKCSVPQLEMDSRYTSATGIGDLNQLSAAIPATRVEVSVSCRNLLDRDTFSKSDPICVLYTQAVGNKEWREFGRTEVIDNTLNPDFVRKFILDYFFEERENLRFDLYDVDSKSPNLSKHDFLGQVFCTLGEIVGSQGSRLEKPIVGIPGRKCGTIILTAEELNCCRDAVLMQFCANKLDKKDFFGKSDPFLVFYRSNEDGSFTICHKTEVVKNTLNPVWQAFKISVRALCNGDYDRTIKVEVYDWDRDGSHDFIGEFTTSYRELARGQSQFNVYEVVNPKKKGKKKKYTNSGTVTLLSFLVETEVSFLDYIKGGTQINFTVAIDFTASNGNPAQPTSLHYMNPYQLNAYGMALKAVGEIVQDYDSDKMFPALGFGAKLPPDGRISHEFALNGNPQNPYCDGIEGVMEAYYRSLKSVQLYGPTNFAPVINHVARYASSVKDGSQYFVLLIVTDGVISDMAQTKESIVNASKLPMSIIIVGVGPAEFDAMVELDGDDVRVSSRGKYAERDIVQFVPFRDYIDRSGNHILSMARLAKDVLAEIPEQFLSYMRARGIKPSPAPPPYTPPTHVLQTQI", "length": 577 }, "evidence": [ { "id": "MGI:1914121", "url": "https://alliancegenome.org/gene/MGI:1914121#orthology", "database": "AGR" }, { "id": "HGNC:23498", "url": "https://alliancegenome.org/gene/HGNC:23498#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100809-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100809-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "E7F5X2", "url": "https://www.uniprot.org/uniprotkb/E7F5X2" } ], "pmid": "" }, { "name": "calcium-dependent phospholipid binding", "id": "GO:0005544", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005544", "evidence": [ { "database": "UniProtKB", "id": "E7F5X2", "url": "https://www.uniprot.org/uniprotkb/E7F5X2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E7F5X2", "url": "https://www.uniprot.org/uniprotkb/E7F5X2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cellular response to calcium ion", "id": "GO:0071277", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071277", "evidence": [ { "database": "UniProtKB", "id": "E7F5X2", "url": "https://www.uniprot.org/uniprotkb/E7F5X2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 312, "end_pos": 314, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F5X2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F5X2" }, { "id": "PS50004", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50004" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2", "eco_id": "ECO_0000259", "start_pos": 5, "end_pos": 138, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 312, "end_pos": 314 }, { "start_pos": 461, "end_pos": 463 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F0Y9-1", "uniprot_ac": "E7F0Y9", "uniprot_id": "E7F0Y9_DANRE", "mass": { "chemical_mass": 131600.0, "monoisotopic_mass": 131600.0 }, "refseq": { "ac": "XP_694444", "name": "uncharacterized protein si:ch211-91p5.3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694444" }, "gene_names": [ { "name": "si:ch211-91p5.3", "type": "recommended", "evidence": [ { "id": "E7F0Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0Y9" } ] }, { "name": "si:ch211-91p5.3", "type": "synonym", "evidence": [ { "id": "XP_694444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694444" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch211-91p5.3 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F0Y9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0Y9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch211-91p5.3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_694444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694444" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_694444.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_694444", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694444" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F0Y9", "url": "https://www.uniprot.org/uniprotkb/E7F0Y9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-91p5.3", "url": "https://www.uniprot.org/uniprotkb/E7F0Y9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131119-65", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131119-65", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000089227", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000089227", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "566084", "url": "https://www.ncbi.nlm.nih.gov/gene/566084", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027897", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027897", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566084", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566084", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PRIDCLA", "url": "https://omabrowser.org/oma/group/PRIDCLA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F0Y9", "url": "https://www.orthodb.org/?gene=E7F0Y9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35083", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35083", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35083:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35083:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15112", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15112", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_694444", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_694444", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TJS1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJS1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TJS1-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TJS1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYM5", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYM5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYM5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYM5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYN4", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IYN4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IYN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0Y9", "url": "https://www.uniprot.org/uniprotkb/E7F0Y9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0Y9-1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131119-65", "url": "https://zfin.org/ZDB-GENE-131119-65", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSTQSSTRFSDENYKNWLKTAESLYILRNRIQNFIEKETETYHSSLRNKQELNGKTCHQNCNDKDINQKSLCQLCECWRKEIVANHNGKYGIHWNNCKPNRWSTDKWEVAKAYMPRGHRDHCEFSHFDVAAILNFMNFCKHFSKIQGHHVRNVINVRNNVMHSPDLKMSNEDMKKHHSTILLLANMLQPQVPELNGLEEEIKQYNNTLDQNFNKPLCEVDGQQINVHTRELLDRENQALKDKIKDIISSFEGNQEENVNGKLQDFKHIMDFLDQNKDLLENLGPEVNKLKEIQTKVDELDEEVSTLKVRMDQLEKEKQDPLLPGIPPRYKNHLFEFCRAKKWLEPVFTETQEAQGYRGKVTVNGQSFTGIRVFNDKKGAHQEVACIALEQMKSQEESTNEPSSSVMQPETSCSSSSGIYFGKVTVDLNLEVESERCPSAEEASEAVYKILWESFHLSAPVQGQTHRSVILEYFNANYFQKPSEYFVQNDDNTTSCKLKLIGPFTFYDKDGSTKKKLADQQAAKVALQHLSGIFNCAPISETEKNFKGILKECLETRGLKSPNYTTVNNPEISEKQVAMSISPDLTNSAASITQAAEKEHSELKSGNICKSAQLPVFQEAACIPVPMLPDPQDSSSPAVVRKKPRIDCLAKTFFGKVTVNLKDVMSERCSSKEEAAEAAYKNLMESFCINAPAEGQTYRSVIIDHFGKYEVQQPIEEFDDDDNNTTICILKFSPFIFYDKDGSTKKKQAEQQAASVALDRLSGIFNCAPVSDDKQNFKGVLKEFLESLGHSNPIYDTKEHKGEIREEPGTGGMTPILSNLSISQSSVMENVEFESISTSVQLPICQESVNVSLDSSVASMRKKPRIDCPEINELLRVYNLMPHVEVENVKCDQGFKCTVKINLEEFTCANKQGYDTKKEAIRKTYLLFGCAVSILNNTDEKTSIAMVKMRFSQNSLPLPQEDVEGSSKLFYCSLKNINYTVDYDGEGSSEDEAKLLALQKALRFLSPLFNYPSLPGADHPEEVLNQLSSILKGASQKDPIVSLVVMNKACVQLSFCDYTMKCTCQSTKKAARNHLSARILGLLGIETDANNANLKNQLDVWFTKNSPPKPVFEDTEVTGAKATFSVQITSCSPDWEENWETAKMKLLEVLKNRFQFLDEKNY", "length": 1162, "header": "tr|E7F0Y9-1|E7F0Y9_DANRE Isoform 1 of Uncharacterized protein si:ch211-91p5.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-91p5.3 PE=1 SV=1 CANONICAL=E7F0Y9-1" }, "isoforms": [ { "isoform_ac": "A0AB32TJS1-1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y9/entry#A0AB32TJS1-1", "sequence": { "sequence": "MSSTQSSTRFSDENYKNWLKTAESLYILRNRIQNFIEKETETYHSSLRNKQELNGKTCHQNCNDKDINQKSLCQLCECWRKEIVANHNGKYGIHWNNCKPNRWSTDKWEVAKAYMPRGHRDHCEFSHFDVAAILNFMNFCKHFSKIQGHHVRNVINVRNNVMHSPDLKMSNEDMKKHHSTILLLANMLQPQVPELNGLEEEIKQYNNTLDQNFNKPLCEVDGQQINVHTRELLDRENQALKDKIKDIISSFEGNQEENVNGKLQDFKHIMDFLDQNKDLLENLGPEVNKLKEIQTKVDELDEEVSTLKVRMDQLEKEKQDPLLPGIPPRYKNHLFEFCRAKKWLEPVFTETQEAQGYRGKVTVNGQSFTGIRVFNDKKGAHQEVACIALEQMKSQEESTNEPSSSVMQPETSCSSSSGIYFGKVTVDLNLEVESERCPSAEEASEAVYKILWESFHLSAPVQGQTHRSVILEYFNANYFQKPSEYFVQNDDNTTSCKLKLIGPFTFYDKDGSTKKKLADQQAAKVALQHLSGIFNCAPISETEKNFKGILKECLETRGLKSPNYTTVNNPEISEKQVAMSISPDLTNSAASITQAAEKEHSELKSGNICKSAQLPVFQEAACIPVPMLPDPQDSSSPAVVRKKPRIDCLAKTFFGKVTVNLKDVMSERCSSKEEAAEAAYKNLMESFCINAPAEGQTYRSVIIDHFGKYEVQQPIEEFDDDDNNTTICILKFSPFIFYDKDGSTKKKQAEQQAASVALDRLSGIFNCAPVSDDKQNFKGVLKEFLESLGHSNPIYDTKEHKGEIREEPGTGGMTPILSNLSISQSSVMENVEFESISTSVQLPICQESVNVSLDSSVASMRKKPRIDCPEINELLRVYNLMPHVEVENVKCDQGFKCTVKINLEEFTCANKQGYDTKKEAIRKTYLLFGCAVSILNNTDEKTSIAMVKMRFSQNSLPLPQEDVEGSSKLFYCSLKNINYTVDYDGEDLRGPLKARQRQRG", "length": 1000, "header": "tr|A0AB32TJS1-1|E7F0Y9_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-91p5.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-91p5.3 PE=1 SV=1 CANONICAL=E7F0Y9-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYM5-1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y9/entry#A0AC58IYM5-1", "sequence": { "sequence": "MSSTQSSTRFSDENYKNWLKTAESLYILRNRIQNFIEKETETYHSSLRNKQELNGKTCHQNCNDKDINQKSLCQLCECWRKEIVANHNGKYGIHWNNCKPNRWSTDKWEVAKAYMPRGHRDHCEFSHFDVAAILNFMNFCKHFSKIQGHHVRNVINVRNNVMHSPDLKMSNEDMKKHHSTILLLANMLQPQVPELNGLEEEIKQYNNTLDQNFNKPLCEVDGQQINVHTRELLDRENQALKDKIKDIISSFEGNQEENVNGKLQDFKHIMDFLDQNKDLLENLGPEVNKLKEIQTKVDELDEEVSTLKVRMDQLEKEKQDPLLPGIPPRYKNHLFEFCRAKKWLEPVFTETQEAQGYRGKVTVNGQSFTGIRVFNDKKGAHQEVACIALEQMKSQEESTNEPSSSVMQPETSCSSSSGIYFGKVTVDLNLEVESERCPSAEEASEAVYKILWESFHLSAPVQGQTHRSVILEYFNANYFQKPSEYFVQNDDNTTSCKLKLIGPFTFYDKDGSTKKKLADQQAAKVALQHLSGIFNCAPISETEKNFKGILKECLETRGLKSPNYTTVNNPEISEKQVAMSISPDLTNSAASITQAAEKEHSELKSGNICKSAQLPVFQEAACIPVPMLPDPQDSSSPAVVRKKPRIDCLAKTFFGKVTVNLKDVMSERCSSKEEAAEAAYKNLMESFCINAPAEGQTYRSVIIDHFGKYEVQQPIEEFDDDDNNTTICILKFSPFIFYDKGKWRGIQVHFNLHCSETLQITLKTHHCSAPNIDMYLQRLSSDGVILFRVCLPPSASK", "length": 797, "header": "tr|A0AC58IYM5-1|A0AC58IYM5_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-91p5.3 isoform X3 OS=Danio rerio OX=7955 GN=si:ch211-91p5.3 PE=1 SV=1 CANONICAL=E7F0Y9-1" }, "locus": {} }, { "isoform_ac": "A0AC58IYN4-1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y9/entry#A0AC58IYN4-1", "sequence": { "sequence": "MQNMIFRMTQIKLIFFIPFPTGQTHRSVILEYFNANYFQKPSEYFVQNDDNTTSCKLKLIGPFTFYDKDGSTKKKLADQQAAKVALQHLSGIFNCAPISETEKNFKGILKECLETRGLKSPNYTTVNNPEISEKQVAMSISPDLTNSAASITQAAEKEHSELKSGNICKSAQLPVFQEAACIPVPMLPDPQDSSSPAVVRKKPRIDCLAKTFFGKVTVNLKDVMSERCSSKEEAAEAAYKNLMESFCINAPAEGQTYRSVIIDHFGKYEVQQPIEEFDDDDNNTTICILKFSPFIFYDKDGSTKKKQAEQQAASVALDRLSGIFNCAPVSDDKQNFKGVLKEFLESLGHSNPIYDTKEHKGEIREEPGTGGMTPILSNLSISQSSVMENVEFESISTSVQLPICQESVNVSLDSSVASMRKKPRIDCPEINELLRVYNLMPHVEVENVKCDQGFKCTVKINLEEFTCANKQGYDTKKEAIRKTYLLFGCAVSILNNTDEKTSIAMVKMRFSQNSLPLPQEDVEGSSKLFYCSLKNINYTVDYDGEGSSEDEAKLLALQKALRFLSPLFNYPSLPGADHPEEVLNQLSSILKGASQKDPIVSLVVMNKACVQLSFCDYTMKCTCQSTKKAARNHLSARILGLLGIETDANNANLKNQLDVWFTKNSPPKPVFEDTEVTGAKATFSVQITSCSPDWEENWETAKMKLLEVLKNRFQFLDEKNY", "length": 721, "header": "tr|A0AC58IYN4-1|A0AC58IYN4_DANRE Computationally mapped isoform of Uncharacterized protein si:ch211-91p5.3 isoform X4 OS=Danio rerio OX=7955 GN=si:ch211-91p5.3 PE=1 SV=1 CANONICAL=E7F0Y9-1" }, "locus": {} }, { "isoform_ac": "E7F0Y9-1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y9/entry#E7F0Y9-1", "sequence": { "sequence": "MSSTQSSTRFSDENYKNWLKTAESLYILRNRIQNFIEKETETYHSSLRNKQELNGKTCHQNCNDKDINQKSLCQLCECWRKEIVANHNGKYGIHWNNCKPNRWSTDKWEVAKAYMPRGHRDHCEFSHFDVAAILNFMNFCKHFSKIQGHHVRNVINVRNNVMHSPDLKMSNEDMKKHHSTILLLANMLQPQVPELNGLEEEIKQYNNTLDQNFNKPLCEVDGQQINVHTRELLDRENQALKDKIKDIISSFEGNQEENVNGKLQDFKHIMDFLDQNKDLLENLGPEVNKLKEIQTKVDELDEEVSTLKVRMDQLEKEKQDPLLPGIPPRYKNHLFEFCRAKKWLEPVFTETQEAQGYRGKVTVNGQSFTGIRVFNDKKGAHQEVACIALEQMKSQEESTNEPSSSVMQPETSCSSSSGIYFGKVTVDLNLEVESERCPSAEEASEAVYKILWESFHLSAPVQGQTHRSVILEYFNANYFQKPSEYFVQNDDNTTSCKLKLIGPFTFYDKDGSTKKKLADQQAAKVALQHLSGIFNCAPISETEKNFKGILKECLETRGLKSPNYTTVNNPEISEKQVAMSISPDLTNSAASITQAAEKEHSELKSGNICKSAQLPVFQEAACIPVPMLPDPQDSSSPAVVRKKPRIDCLAKTFFGKVTVNLKDVMSERCSSKEEAAEAAYKNLMESFCINAPAEGQTYRSVIIDHFGKYEVQQPIEEFDDDDNNTTICILKFSPFIFYDKDGSTKKKQAEQQAASVALDRLSGIFNCAPVSDDKQNFKGVLKEFLESLGHSNPIYDTKEHKGEIREEPGTGGMTPILSNLSISQSSVMENVEFESISTSVQLPICQESVNVSLDSSVASMRKKPRIDCPEINELLRVYNLMPHVEVENVKCDQGFKCTVKINLEEFTCANKQGYDTKKEAIRKTYLLFGCAVSILNNTDEKTSIAMVKMRFSQNSLPLPQEDVEGSSKLFYCSLKNINYTVDYDGEGSSEDEAKLLALQKALRFLSPLFNYPSLPGADHPEEVLNQLSSILKGASQKDPIVSLVVMNKACVQLSFCDYTMKCTCQSTKKAARNHLSARILGLLGIETDANNANLKNQLDVWFTKNSPPKPVFEDTEVTGAKATFSVQITSCSPDWEENWETAKMKLLEVLKNRFQFLDEKNY", "length": 1162, "header": "tr|E7F0Y9-1|E7F0Y9_DANRE Isoform 1 of Uncharacterized protein si:ch211-91p5.3 isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-91p5.3 PE=1 SV=1 CANONICAL=E7F0Y9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:566084", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566084", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { "start_pos": 492, "end_pos": 494, "annotation": "n_glycosylation_sequon" }, { "start_pos": 563, "end_pos": 565, "annotation": "n_glycosylation_sequon" }, { "start_pos": 723, "end_pos": 725, "annotation": "n_glycosylation_sequon" }, { "start_pos": 724, "end_pos": 726, "annotation": "n_glycosylation_sequon" }, { "start_pos": 819, "end_pos": 821, "annotation": "n_glycosylation_sequon" }, { "start_pos": 850, "end_pos": 852, "annotation": "n_glycosylation_sequon" }, { "start_pos": 936, "end_pos": 938, "annotation": "n_glycosylation_sequon" }, { "start_pos": 978, "end_pos": 980, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 206, "end_pos": 208 }, { "start_pos": 492, "end_pos": 494 }, { "start_pos": 563, "end_pos": 565 }, { "start_pos": 723, "end_pos": 725 }, { "start_pos": 724, "end_pos": 726 }, { "start_pos": 819, "end_pos": 821 }, { "start_pos": 850, "end_pos": 852 }, { "start_pos": 936, "end_pos": 938 }, { "start_pos": 978, "end_pos": 980 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FFE7-1", "uniprot_ac": "E7FFE7", "uniprot_id": "E7FFE7_DANRE", "mass": { "chemical_mass": 95294.0, "monoisotopic_mass": 95294.0 }, "refseq": { "ac": "XP_017210271", "name": "meiosis-specific coiled-coil domain-containing protein MEIOC isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210271" }, "gene_names": [ { "name": "moto", "type": "recommended", "evidence": [ { "id": "E7FFE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FFE7" } ] }, { "name": "moto", "type": "synonym", "evidence": [ { "id": "XP_017210271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210271" } ] } ], "protein_names": [ { "name": "Meiosis-specific coiled-coil domain-containing protein MEIOC isoform X1", "type": "synonym", "evidence": [ { "id": "E7FFE7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FFE7/entry#names_and_taxonomy" } ] }, { "name": "meiosis-specific coiled-coil domain-containing protein MEIOC isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017210271", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210271" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 15, 2017 this sequence version replaced XP_017210271.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017210271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210271" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FFE7", "url": "https://www.uniprot.org/uniprotkb/E7FFE7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "moto", "url": "https://www.uniprot.org/uniprotkb/E7FFE7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070117-1657", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070117-1657", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000090664", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000090664", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100538154", "url": "https://www.ncbi.nlm.nih.gov/gene/100538154", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027963", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027963", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100538154", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100538154", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7FFE7", "url": "https://www.orthodb.org/?gene=E7FFE7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33861", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33861", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33861:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33861:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15189", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15189", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017210271", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017210271", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AB32TK87", "url": "https://www.uniprot.org/uniprotkb/A0AB32TK87", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AB32TK87-1", "url": "https://www.uniprot.org/uniprotkb/A0AB32TK87-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FFE7", "url": "https://www.uniprot.org/uniprotkb/E7FFE7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FFE7-1", "url": "https://www.uniprot.org/uniprotkb/E7FFE7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070117-1657", "url": "https://zfin.org/ZDB-GENE-070117-1657", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEGNVNNAGKSKISVDANGARTILDRFQNSGTDSYFTTYKPQTSFSDSRFLSQSSNSFSNCQMQDCAPLPYTVWSTQEDWPQAITNSRNSINGNNCGSEADLYGLVSDILDEPDSVDPYPSYENRLPSSLKGVWSPKLRENNMQYFNNEMQMPPISGFPSNNINPKPVTNVCPQPLGREFQQWAEIQNFNGFDSPRNFSSCNGGADIYSQDLPCPPGLNTPPYTTRKPEYITPDKEEGYFNPTNSTSDYINTANSYYSSQNSDDSYFNSSHDFSPMNKDKLRNIQSFSVQDVSKLAFLLAEQDMNYCKEPTQNGFLTQRNYEEIMAEQKSHPFQRMSELISQKPNFKNEVTRNLLEQRGGKAEDKKTLLQRHYNTNEFSGFRSSKAFSPTVIPPALYPNKETSLMESGITQTSVNLFHPLQPNHCQIQANIPAKTSSRNESQGFANLTTAGSAQLLPSQQLFRPAGRVPTDLSQGNAVNLHGAIGQVSLEALGKGTGKVDISDFDLKLENNRFTAGLMLDGRFNPRSSMKPKLPEAENKAGLLQNPYHGLASLYERQVRHNEASSSSTTPSHPFPFLYQMGDPRKSQYHSQPSLPFCSVPIINVSERLPDADISPFSPYLQECAGLSQASGDGLFSGFLSAMALPKLGKALGSPNSQLHFYLEECYEQWRMLEKERKRAEAILTKAYLGKLVSMVVTSSSLPKMPPNPSRVDRLIVDQLREQARVTGLLGKMEQLRSFPLHANISSTLDRHLEVIYITQARRKEEFINASNRQRQPAAFFREDREILMLASAVKDLCISTRKARTALWCALQMTLPKTSSYQEEELDKGTCSPLGPDSPEQCRLERSQTTL", "length": 851, "header": "tr|E7FFE7-1|E7FFE7_DANRE Isoform 1 of Meiosis-specific coiled-coil domain-containing protein MEIOC isoform X1 OS=Danio rerio OX=7955 GN=moto PE=4 SV=1 CANONICAL=E7FFE7-1" }, "isoforms": [ { "isoform_ac": "A0AB32TK87-1", "url": "https://www.uniprot.org/uniprotkb/E7FFE7/entry#A0AB32TK87-1", "sequence": { "sequence": "MEGNVNNAGKSKISVDANGARTILDRFQNSGTDSYFTTYKPQTSFSDSRFLSQSSNSFSNCQMQDCAPLPYTVWSTQEDWPQAITNSRNSINGNNCGSEADLYGLVSDILDEPDSVDPYPSYEKLPSSLKGVWSPKLRENNMQYFNNEMQMPPISGFPSNNINPKPVTNVCPQPLGREFQQWAEIQNFNGFDSPRNFSSCNGGADIYSQDLPCPPGLNTPPYTTRKPEYITPDKEEGYFNPTNSTSDYINTANSYYSSQNSDDSYFNSSHDFSPMNKDKLRNIQSFSVQDVSKLAFLLAEQDMNYCKEPTQNGFLTQRNYEEIMAEQKSHPFQRMSELISQKPNFKNEVTRNLLEQRGGKAEDKKTLLQRHYNTNEFSGFRSSKAFSPTVIPPALYPNKETSLMESGITQTSVNLFHPLQPNHCQIQANIPAKTSSRNESQGFANLTTAGSAQLLPSQQLFRPAGRVPTDLSQGNAVNLHGAIGQVSLEALGKGTGKVDISDFDLKLENNRFTAGLMLDGRFNPRSSMKPKLPEAENKAGLLQNPYHGLASLYERQVRHNEASSSSTTPSHPFPFLYQMGDPRKSQYHSQPSLPFCSVPIINVSERLPDADISPFSPYLQECAGLSQASGDGLFSGFLSAMALPKLGKALGSPNSQLHFYLEECYEQWRMLEKERKRAEAILTKAYLGKLVSMVVTSSSLPKMPPNPSRVDRLIVDQLREQARVTGLLGKMEQLRSFPLHANISSTLDRHLEVIYITQARRKEEFINASNRQRQPAAFFREDREILMLASAVKDLCISTRKARTALWCALQMTLPKTSSYQEEELDKGTCSPLGPDSPEQCRLERSQTTL", "length": 850, "header": "tr|A0AB32TK87-1|E7FFE7_DANRE Computationally mapped isoform of Meiosis-specific coiled-coil domain-containing protein MEIOC isoform X1 OS=Danio rerio OX=7955 GN=moto PE=4 SV=1 CANONICAL=E7FFE7-1" }, "locus": {} }, { "isoform_ac": "E7FFE7-1", "url": "https://www.uniprot.org/uniprotkb/E7FFE7/entry#E7FFE7-1", "sequence": { "sequence": "MEGNVNNAGKSKISVDANGARTILDRFQNSGTDSYFTTYKPQTSFSDSRFLSQSSNSFSNCQMQDCAPLPYTVWSTQEDWPQAITNSRNSINGNNCGSEADLYGLVSDILDEPDSVDPYPSYENRLPSSLKGVWSPKLRENNMQYFNNEMQMPPISGFPSNNINPKPVTNVCPQPLGREFQQWAEIQNFNGFDSPRNFSSCNGGADIYSQDLPCPPGLNTPPYTTRKPEYITPDKEEGYFNPTNSTSDYINTANSYYSSQNSDDSYFNSSHDFSPMNKDKLRNIQSFSVQDVSKLAFLLAEQDMNYCKEPTQNGFLTQRNYEEIMAEQKSHPFQRMSELISQKPNFKNEVTRNLLEQRGGKAEDKKTLLQRHYNTNEFSGFRSSKAFSPTVIPPALYPNKETSLMESGITQTSVNLFHPLQPNHCQIQANIPAKTSSRNESQGFANLTTAGSAQLLPSQQLFRPAGRVPTDLSQGNAVNLHGAIGQVSLEALGKGTGKVDISDFDLKLENNRFTAGLMLDGRFNPRSSMKPKLPEAENKAGLLQNPYHGLASLYERQVRHNEASSSSTTPSHPFPFLYQMGDPRKSQYHSQPSLPFCSVPIINVSERLPDADISPFSPYLQECAGLSQASGDGLFSGFLSAMALPKLGKALGSPNSQLHFYLEECYEQWRMLEKERKRAEAILTKAYLGKLVSMVVTSSSLPKMPPNPSRVDRLIVDQLREQARVTGLLGKMEQLRSFPLHANISSTLDRHLEVIYITQARRKEEFINASNRQRQPAAFFREDREILMLASAVKDLCISTRKARTALWCALQMTLPKTSSYQEEELDKGTCSPLGPDSPEQCRLERSQTTL", "length": 851, "header": "tr|E7FFE7-1|E7FFE7_DANRE Isoform 1 of Meiosis-specific coiled-coil domain-containing protein MEIOC isoform X1 OS=Danio rerio OX=7955 GN=moto PE=4 SV=1 CANONICAL=E7FFE7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100538154", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100538154", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "meiotic cell cycle", "id": "GO:0051321", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051321", "evidence": [ { "database": "UniProtKB", "id": "E7FFE7", "url": "https://www.uniprot.org/uniprotkb/E7FFE7" } ], "pmid": "" }, { "name": "female meiosis I", "id": "GO:0007144", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007144", "evidence": [ { "database": "UniProtKB", "id": "E7FFE7", "url": "https://www.uniprot.org/uniprotkb/E7FFE7" } ], "pmid": "" }, { "name": "mRNA stabilization", "id": "GO:0048255", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048255", "evidence": [ { "database": "UniProtKB", "id": "E7FFE7", "url": "https://www.uniprot.org/uniprotkb/E7FFE7" } ], "pmid": "" }, { "name": "male meiosis I", "id": "GO:0007141", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007141", "evidence": [ { "database": "UniProtKB", "id": "E7FFE7", "url": "https://www.uniprot.org/uniprotkb/E7FFE7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7FFE7", "url": "https://www.uniprot.org/uniprotkb/E7FFE7" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7FFE7", "url": "https://www.uniprot.org/uniprotkb/E7FFE7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 197, "end_pos": 199, "annotation": "n_glycosylation_sequon" }, { "start_pos": 244, "end_pos": 246, "annotation": "n_glycosylation_sequon" }, { "start_pos": 268, "end_pos": 270, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" }, { "start_pos": 446, "end_pos": 448, "annotation": "n_glycosylation_sequon" }, { "start_pos": 603, "end_pos": 605, "annotation": "n_glycosylation_sequon" }, { "start_pos": 743, "end_pos": 745, "annotation": "n_glycosylation_sequon" }, { "start_pos": 768, "end_pos": 770, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 197, "end_pos": 199 }, { "start_pos": 244, "end_pos": 246 }, { "start_pos": 268, "end_pos": 270 }, { "start_pos": 439, "end_pos": 441 }, { "start_pos": 446, "end_pos": 448 }, { "start_pos": 603, "end_pos": 605 }, { "start_pos": 743, "end_pos": 745 }, { "start_pos": 768, "end_pos": 770 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E9QDC4-1", "uniprot_ac": "E9QDC4", "uniprot_id": "E9QDC4_DANRE", "mass": { "chemical_mass": 37029.0, "monoisotopic_mass": 37029.0 }, "refseq": { "ac": "NP_001314951", "name": "zinc finger protein 1113", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314951" }, "gene_names": [ { "name": "znf1113", "type": "recommended", "evidence": [ { "id": "E9QDC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QDC4" } ] }, { "name": "si:ch211-286l10.2", "type": "synonym", "evidence": [ { "id": "NP_001314951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314951" }, { "id": "E9QDC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QDC4" } ] }, { "name": "znf1113", "type": "synonym", "evidence": [ { "id": "NP_001314951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314951" } ] } ], "protein_names": [ { "name": "Zinc finger protein 1113", "type": "synonym", "evidence": [ { "id": "E9QDC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QDC4/entry#names_and_taxonomy" } ] }, { "name": "gastrula zinc finger protein XlCGF8.2DB", "type": "synonym", "evidence": [ { "id": "NP_001314951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314951" } ] }, { "name": "zinc finger protein 1113", "type": "synonym", "evidence": [ { "id": "NP_001314951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314951" } ] }, { "name": "zinc finger protein 37 homolog", "type": "synonym", "evidence": [ { "id": "NP_001314951", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314951" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC167473.1, SRR26395062.1433363.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476737, SAMEA4476738 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Jun 2, 2016 this sequence version replaced XP_002661613.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001314951", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314951" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "E9QDC4", "url": "https://www.uniprot.org/uniprotkb/E9QDC4#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QDC4", "url": "https://www.uniprot.org/uniprotkb/E9QDC4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "znf1113", "url": "https://www.uniprot.org/uniprotkb/E9QDC4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110913-161", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110913-161", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000096172", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000096172", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100330526", "url": "https://www.ncbi.nlm.nih.gov/gene/100330526", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050758", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050758", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100330526", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330526", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IHTFERP", "url": "https://omabrowser.org/oma/group/IHTFERP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E9QDC4", "url": "https://www.orthodb.org/?gene=E9QDC4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23234", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23234", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001314951", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314951", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E9QDC4", "url": "https://www.uniprot.org/uniprotkb/E9QDC4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QDC4-1", "url": "https://www.uniprot.org/uniprotkb/E9QDC4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110913-161", "url": "https://zfin.org/ZDB-GENE-110913-161", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDPQEQTDLIEEYEGSKQEEHHVKIEEKTHLQTDGVLKRRDKNRFTCTQCGRSFGRKGDLRIHMRIHTGEKISTCTQCGKSFGRKDHLKIHMMIHTGEKPFTCTQCGKSFSYSSHLNEHMRIHTGEKPFTCTQCGKSFSHLSSLNQHIRIHTGEKPFTCTQCGKSFRHSLILKQHIRIHTGEKPFTCTQCGKSFRQSSSLNYHKKIHTGEKPFTCTQCGKSFSQSSSFNQHMRIHTGEKPFTCTQCGKSFSQSSSFNYHMRIHTGEKPFKCTQCGKSFRISTSLNLHMMSHTREKPFTCT", "length": 321, "header": "tr|E9QDC4-1|E9QDC4_DANRE Isoform 1 of Zinc finger protein 1113 OS=Danio rerio OX=7955 GN=znf1113 PE=4 SV=3 CANONICAL=E9QDC4-1" }, "isoforms": [ { "isoform_ac": "E9QDC4-1", "url": "https://www.uniprot.org/uniprotkb/E9QDC4/entry#E9QDC4-1", "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDPQEQTDLIEEYEGSKQEEHHVKIEEKTHLQTDGVLKRRDKNRFTCTQCGRSFGRKGDLRIHMRIHTGEKISTCTQCGKSFGRKDHLKIHMMIHTGEKPFTCTQCGKSFSYSSHLNEHMRIHTGEKPFTCTQCGKSFSHLSSLNQHIRIHTGEKPFTCTQCGKSFRHSLILKQHIRIHTGEKPFTCTQCGKSFRQSSSLNYHKKIHTGEKPFTCTQCGKSFSQSSSFNQHMRIHTGEKPFTCTQCGKSFSQSSSFNYHMRIHTGEKPFKCTQCGKSFRISTSLNLHMMSHTREKPFTCT", "length": 321, "header": "tr|E9QDC4-1|E9QDC4_DANRE Isoform 1 of Zinc finger protein 1113 OS=Danio rerio OX=7955 GN=znf1113 PE=4 SV=3 CANONICAL=E9QDC4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2002", "authors": "Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA", "evidence": [ { "database": "UniProtKB", "id": "E9QDC4", "url": "https://www.uniprot.org/uniprotkb/E9QDC4" } ], "reference": [ { "type": "PubMed", "id": "12477932", "url": "https://glygen.org/publication/PubMed/12477932" } ] }, { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "E9QDC4", "url": "https://www.uniprot.org/uniprotkb/E9QDC4" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] } ], "pathway": [ { "id": "dre:100330526", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330526", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4K7S6-1", "protein_name": "Molting defective, isoform D", "gene_name": "mld", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSANRRRRSASAASSIAAETATAATAATAEAISTAPSKEQLSPPIAGGSASADEDLLEMPRICRCCCKRDLKLLGLFEASQPTLANTTVASASAAASVASNKSSGTLAKTCATEAETETPQTLSANPVNPGTKATSSPSEAATTLSTSTRPASASFSSTSFSTSTSPMRRRTTNTTAPSASPAPRGRSSDNAVDYTLSGAHSSMDIVLEEMTIWMLNINRDDGLPQEICRQCMAQFLMVAKFRRKCVRMQQRLQDFAQEISDRQTARQAKRQQKVQKKTHDRWLQLEPTSHEEQQPIRKRRMVSESDGDSTAAAAAAEAATATATTPAKQVRTDFESLPPPKPSPQQHRVRKYRTLSIDCEMERPAASINASSMPWKTKAARKELSENWASSCSTAVMSPNRQRSSTSSSEHMSDLSVGPCCGFESDSNPSSTSNSARRTVILVKQQSPEKTSPMYDLMPRRGRRPRKAPIYMPAKRQRRSLVRKEPLYRKAQPVNEENKKSDQKDIYPKESRMEGLAPSCDEAIDSTSDAPMEVASNVVQKKCDEICLNGLIDSRNQLGAMEMEPVNEMIASNGVDKELTLSVQNNKETTSEEQIFEATSVIKESVQPEQSAEDIQVRTEIESIANDIRAEADLVQSEELTSSTETSESQPKAVEQLESMGKQESYALPQNMEAHESVQQTQTVDESDSADQREIIVSIPLEVLDENLQRRLCVDPETEAANRQSADPKEFALRPDDVNNNENDENFCQSATADSFNSAVALRTNKIEATPPGGTDSDDTDTDEVPIVPSGPTPMDFMAEFAKHCANGIEQLKVTTPVPSPTPSDLVPLNDLEAKQKLEVEMNDVETTLNGILNEMQDQHMYTPNCAHIDEFLTPADYATLTEQESSVSSPPNPFEQSSVAEPKDEKPSATEDPFDNSNFTNELIGFQNDIPCFENIETPEEGQNLHLELTQFLRDLQPSQSDPPAGEQVEKIEMETQPSTVQMDVQSNLPVQAADTQPQNESANHSPFESPISSPQVQSQIELQMEPQIETQMQPQIETRMQHDVLSVQSPQNHQPQVQSHDQSQMQHQIPPQIEPQIEVQNQEQNTLQLVPQAQHQVVPHVQLQSQLVPHVQTQGTTTTVTYEQIYQQHIVQQTVQQSSNKMQVISLPSAGSETTRQWQTQQSQQQQQVQWSSVGGLEAIKSAPVESVAPTTTTYYISASDLYPQQTETYTMLQPASNESYVIEQVNHQQQHCQQQIQMSQQQHQRQHQQQQAQQQQQPIMILIQQPEIQQPVASASNPQQAPLHIYNAATSNDVHQMQHTQRQQIRQQYQHQQYQRLQQPQQTRVVQSHPVLGMPGATSISTKVTPIPVTAARGRPLTLKCRFCHNGPRFSSSLEYSRHIIDLHPAVAPFNCPHCPMAFAGRTKRSQHILSHHVVQQYQCGQCSHVFPAQKALDVHIQRFHMTLKTDPSGAVKVEDVQLQITSERRPRGRPYKPRLQLQQHQLQPQQKLQVQQHQQQQKALQQLPQAQHHQQQQQPQLQQEVLQQVQQLQVQVQPQQHQQHQQVLQVQQPQQQPLMQPQSPHPSTVEMQASPTTPRKILCCPDCEDCTSGHSHANEQFEELQTLQAPPTVLTPPSTIVSVPSPQPMVYSQHITMPSPEQSEPDSTTTLRQYRKRGVIVGPQGPLHLATPVASPSPSSSPSSSTVDHIPPASPATPASPAPPPSPAVASTVQVSELRTSHHCLYCEERFTNEISLKKHHQLAHGALTTMPYVCTICKRGYRMRTALHRHMESHDVEGRPYECNICRVRFPRPSQLTLHKITVHLLSKPHTCDECGKQFGTESALKTHIKFHGELGYQCDGCDRTFEYLKELRKHRRTHSEMFYKCKFCPSSFMRFTNFRAHMKTHLPLGVFRNEDAASKSPSNNNSHASSDKLENPATPIEETPLTPMSSGGHLYHSPDEYPNSVESCAGNSVALESYATTP", "length": 1965 }, "evidence": [ { "id": "HGNC:32464", "url": "https://alliancegenome.org/gene/HGNC:32464#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A0G2JZD8-1", "protein_name": "Zinc finger protein 729", "gene_name": "Zfp729", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "EMLSFRDVAIDFSAEEWECLDLAQWKLYRDVMLENYNNLVFLGLASCKPYLVTFLEQIQEPSDVKGRATTTMHPGGKCCTCKVCGRVFEWTKVFQNHQIIDLGVKGYECEECTKYTHIPSLLPEEKTIHTVEKPYKCEVCGKAFCIPLLLSKHKIIHTEENPYKCDLCGKAFQHPSRLSRHKKIHSGDKPYKCEVCGKAFHFPSLLLVHKRIHTGEKPYKCEVCGKAFHYPSILSKHKRIHTGEKPYKCEVCGKAFHISSFLSKHKIIHRGEKPYKCDVCGKAFHYPSRLSNHKKIHSGEKPYKCEVCGKAFRILSLLSKHKIIHTEENPYKCEVCGKAFDYPSRLSTHSKMHTEEKPYKCEACGKAFRSLSSLSKHRRIHTGDNYYNSEVCGKAFIYPLRLSKHKKICTGEKPYKCEVCGKAFNDSLVLSKHRAIHTGEKLYKCDVCGKAFYYPSRLNNHRKIHSGEKPYQCEECGKAFCFPSSLSKHKRIHTGEKPYKCKECDKAFRSLSSLSKHRRIHTGEKPYKCEVCGKAFHYPSLLSKHKITHTEEKPYKCEVCGQGFHVPSKLSHHKIIHTGESPYKCEVCGKAFCIPLLLSKHKISHTGENHSNSQLSKKAFIYPSRLSKHKKIHKRVKPYKCEVCGKAFRFPSLLLIHKGIHTGEKPYKCEECGKAFYYPSLLSKHKRVHTGEKPYQCEVCGKGFHVSSSLSKHRIIHTGEKPYKCEVCEKAFRFSSSLSKHKRIHTGKKPYKCEECGKAFHFPSLLSKHKISHTGEKPYNCDLCGKAFYYPSLLSKHKMIHTGEKPHKCDICGKAFHYPSKLSNHKKIHTGEKPYKCEVCGNVFCFASSLSKHKRIHTGENPYKCDVCGKAFYYPSLLCHHKIIHTGEKPYKCEVCGKAFHYPSLLSKHKIIHTGKKPYKCEVCGKAFHYPSRLSKHKKIHGAGEMAQELRELATLSRS", "length": 959 }, "evidence": [ { "id": "HGNC:32464", "url": "https://alliancegenome.org/gene/HGNC:32464#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6A1R7-1", "protein_name": "Zinc finger protein 729b", "gene_name": "Zfp729b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSFRDVAIDFSAEEYECLDPAQWKLYRDVMLENYSNLVFLGLASAKPYLVTFLEQTQEPSDVKGGTATIKHPVEKCCTCKECGKVFEWTKVFQNHQIIDLGVKGYKCEECTKYTHIPSLLPEEKTIHTVEKPYKCEVCGKAFCIPLLLSKHKIIHTGENPYKCDVCGKAFQHPSRLSRHKKIHSGDKPYKCEVCGKAFHFPSLLLVHKRIHTGEKPYKCEVCGKAFHYPSILSKHKRIHTGEKPYKCEVCGKAFHISSFLSKHKIIHRGEKPYKCDICGKAFHYPSRLSNHRKIHSEEKPYKCEVCGKAFRFLSLLSKHQIIHREENPYKCEVCGKAFDYPSRLSTHSKMHTEEKPYKCEACGKAFRSLSSLSKHRRIHTGDNYYNSEVCGKAFVYPSRLSKHKICTGEKPYKCEVCGKAFHVASLLSKHRTVHTGEKLYKCDVCGKAFYYPSRLSNHKRIHTGEKPYQCEVCGKAFCFPPSLSKHKRIHTGEKPYKCKECGKAFRFPSSLSAHKKIHTGEKPYKCDVCGKAFHYPSLLSKHKIIHTGEKPYKCEVCGQAFHVASKLSHHKIIHTGEKPYKCEICGKAFHYSSLLSKHKIIHTGKKPYKCDICDKAFYYPSRLSSHTKMHTGEKPYKCEVCGKAFCSPSSLSKHKRIHKVEKAYSCEVCGKVFCIPLLLSKHKRIHLGESHCNSEICSMAFVYPSRLPKHKKNHTREKPYKCEVCGKAFDYPSRLSKHKKIHTRVKPYKCEVCGKAFHFVSLLLVHKGIHTGEKPYKCEECGKAFYYPSLLSKHKIIHTGEKPYQCEVCGKGFHVSSSLSKHRRIHTGEKPYKCEVCEKAFRFSSSLSKHKRIHTGKKPYKCEECGKAFHFPSLLSKHKISHTREKPYNCDLCGKAFYYPSLLSKHKMIHTGEKPHKCDVCGKAFHYPSKLSNHKKIHTGEKPYKCDICGNVFRFPSSLSEHKRTHTGENPYKCEVCGKAFHVPSKLSHHKIIHTGEKPYKCEVCGKAFHYPSLLSKHKIIHTGKKPYKCEVCGKAFHYPSRLSKHKKIHGAREMSQGLRALVALPEILSSIPSNYIVAHNHL", "length": 1084 }, "evidence": [ { "id": "HGNC:32464", "url": "https://alliancegenome.org/gene/HGNC:32464#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0AB32TPY2-1", "protein_name": "Uncharacterized protein znf1085 isoform X1", "gene_name": "znf1085", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAFIKEESEDVKIEETFTVKQEDLQEQTDLIEENEGRKEEEHHVKIEEKTHLQTDGILKRGDKNSFTCTQCGKSYGSKDYLKIHMMIHTGEKLFTCPQCGKSFGRKRELKIHKRIHTGEKPYTCTRCGKSFSQSSNLNQHMRIHTGEKPFTCTQCGKSFNRSSSLNEHMMIHTGEKPFTCTQCGKSFGRNFDLKIHMMIHTGENPFRCTHCGKSFSQSSYLNQHMRIHTRENPFTCTQCGKSFHRSSSLNNHKTIHTREKPFTCTQCGKTFNNSSHLYEHMRIHTGEKPFTCTQCGKSFSLSSNLNRHMRIHTREKPFTCTQCGKSFICSSSLNLHIMSHTGEKLALKQRSQWTFFPMDFHSYARECVRQETKFVCQVSQFTALQSSSLVNSDLQNRIT", "length": 399 }, "evidence": [ { "id": "HGNC:32464", "url": "https://alliancegenome.org/gene/HGNC:32464#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TT05-1", "protein_name": "Uncharacterized protein si:dkey-40j3.3 isoform X1", "gene_name": "si:dkey-40j3.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MKMAFIKEESEDVKIEETFTVKQEDLQEQIGWFHSQTPTQSYRDLIKDYEESKEEHHVKIEDKTHLVTDGILKVRDKSCLTCTQCGKSLASKSKLKTHMRIHTGEKPFTCYQYGKSFSKSSLYRHKKIHTGKKTFTCTQCGKSFNCSSHLNQHIRIHTGEKPFRCTQCGKSFNCSSHLNEHMMIHTGEKPFTCTQCGKSFSKSSSLYRHMKIHTGEKPYTCTECRKSFSQSSSLNLHMRIHTGEKPFTCTECGNSFSKSSSLYRHMKIHTGEKPFTCTECGKSFIQSSCLNVHMRIHTGEKPFTCTQCGKSFIHSSHLNQHLMIHTGEKPFKCPQCGKSFSQSYLKKHMKIHTGVREYMCLECEKTFITAAELKRHKRIHTGEKPYKCSQCSKRFAHSGTLKAHQRIHTGDKL", "length": 413 }, "evidence": [ { "id": "HGNC:32464", "url": "https://alliancegenome.org/gene/HGNC:32464#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AC58JE90-1", "protein_name": "Uncharacterized protein znf1032 isoform X1", "gene_name": "znf1032", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MTFIKEESEDVKIEETFTVKQEDLQEQTDLIVLKEETQHWNKMEEPHQEITADEKPTLTEKTSSLGRPRKSKTECNFSSKQRRKSFIQKRNLGDHMRVHTREKPYTCEQCGKSFGKKRSLKTHMRIHTGERPYTCQQCGKSFKQIGTLKGHMRIHTGERPYTCQQCGKSFKQSATLKGHMRSHTGERPYTCQQCGQSFYYAGNFAAHKRIHTREKPYTCQQCGKSFKQSGTLKGHMRIHNGGKTQCGKSFAQKQKLDTHMTIHTGEKPYTCTECGKSFTCKSSLINHMKTHTREKLFACNQCGKSFTCKANLMNHMDGHTGTIVFICDQCGKSLTRKDYIKQHMKTHSREDRFRCRECGKSFKQKINLSAHMKLHNAEQSPQH", "length": 383 }, "evidence": [ { "id": "HGNC:32464", "url": "https://alliancegenome.org/gene/HGNC:32464#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A6NN14-1", "protein_name": "Zinc finger protein 729", "gene_name": "ZNF729", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGAPGSLEMGPLTFRDVTIEFSLEEWQCLDTVQQNLYRDVMLENYRNLVFLGMAVFKPDLITCLKQGKEPWNMKRHEMVTKPPVMRSHFTQDLWPDQSTKDSFQEVILRTYARCGHKNLRLRKDCKSANEGKMHKEGYNKLNQCRTATQRKIFQCNKHMKVFHKYSNRNKVRHTKKKTFKCIKCSKSFFMLSCLIRHKRIHIRQNIYKCEERGKAFKSFSTLTKHKIIHTEDKPYKYKKCGNAFKFSSTFTKHKRIHTGETPFRCEECGKAFNQSSNLTDHKRIHTGEKTYKCEECGKAFKGSSNFNAHKVIHTAEKPYKCEDCGKTFNHFSALRKHKIIHTGKKPYKREECGKAFSQSSTLRKHEIIHTGEKPYKCEECGKAFKWSSKLTVHKVVHTGEKPYKCEECGKAFSQFSTLKKHKIIHTGKKPYKCEECGKAFNSSSTLMKHKIIHTGEKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFNHFSDLRRHKIIHTGKKPYKCEECGKAFSQSSTLRNHQIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTREKLYKCEECGKAFNNSSILAKHKIIHTGKKPYKCEECGKAFRQSSHLTRHKAIHTGEKPYKCEECGKAFSHFSALRRHKIIHTGKKPYKCEECGKAFSHFSALRRHKIIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTAEKPCKCEECGKSFKHFSALRKHKVIHTREKLYKCEECVKAFNSFSALMKHKVIHTGEKPYKCEECGKAFKWSSKLTVHKVIHTGEKPCKCEECGKAFKHFSALRKHKVIHTGKKPYKCEECGKAFSQSSSLRKHEIIHSGEKPYKCEECGKAFKWLSKLTVHKVIHTAEKPCKCEECGKAFKHFSALRKHKIIHTGKKPYKCEECGKAFNDSSTLMKHKIIHTGKKPYKCAECGKAFKQSSHLTRHKAIHTGEKPYKCEECGKDFNNSSTLKKHKLIHTREKLYKCEECVKAFNNFSALMKHKIIHTGEKPYKCEECGKAFKWSSKLTEHKVIHTGEKPCKCEECDKAFKHFSALRKHKVIHTGKKPYQCDECGKAFNNSSTLTKHKIIHTGEKPYKCEECGKAFSQSSILTKHKIIHSVEKPYKCEECGKAFNQSSHLTRHKTIHTGEKPYKCEECGKAFIQCSYLIRHKTIHTREKPTNVKKVPKLLSNPHTLLDKTIHTGEKPYKCEECAKAF", "length": 1252 }, "evidence": [ { "id": "HGNC:32464", "url": "https://alliancegenome.org/gene/HGNC:32464#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110913-161", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110913-161#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B8JJX8-1", "protein_name": "Zinc finger protein 738", "gene_name": "Zfp738", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEVGAGSSAIFQEMLSFRDVAIDFSAEEWECLEPAQLDLYRDVMLENYSNLVFLGLASSKPYLVTCLEQIQEPSDVKRGAATSMLPERKCYKCKECGKVSEWTKVFQNHQMLDLGMNYYKCEECAKSFHSPSLSSEENRIHAGEKPYKCEVCGKAFCIPLLLSKHKIIHKGENLYKCEVCGKAFQHPSRLSRHKKIHSEEKPYKCEVCGKAFHFPSLLLVHKRVHTGEKPYKCTVCGKAFHYPSIFSKHKRIHTGEKPYKCEECGKAFHISSFLSKHKIIHRGEKPYKCEVCGKAFHYPSRLSNHKKIHSGEKPFKCEVCGKAFRILSLLSKHKIIHTEENPYKCEVCGKAFDYPSRLSNHAEMHTREKPYKCEVCQKAFRSLSSFSKHKRIHTKDNYYNSELCGKAFIYPSRLSKHKKICAGEKPYKCEVCGKAFHVASLLSKHRTIHTGEKLYKCEVCGKAFYYPSRLSNHKKIHTGEKPFQCEVCGKAFCFPSSLSKHKRIHTGEKPYKCKECGKAFRSLSSLSKHKRIHTGEKPYKCEECGKAFHYPSLLSKHKIIHTGEKPYKCDICDQAFHVPSKLSHHKIIHRGEKPHKCEVCGKAFHYPSRLSNHKKIHSEEKPYKCEVCGKAFRILSLLSKHKIIHTEENPYKCEVCGKAFDYPSRLSTHAKMHTREKPYKCEVCQNAFRSLSSLSKHKIIHKEEKPYKSDICGQAFHVPSKLSHHKIIQTGEKPYKCEVCGKAFCIPLLVSKHKRVHTGENPYNSQVYNKAFIYPLRLSKHKKICTKEKPYKC", "length": 793 }, "evidence": [ { "id": "HGNC:32464", "url": "https://alliancegenome.org/gene/HGNC:32464#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E9QDC4", "url": "https://www.uniprot.org/uniprotkb/E9QDC4" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E9QDC4", "url": "https://www.uniprot.org/uniprotkb/E9QDC4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E9QDC4", "url": "https://www.uniprot.org/uniprotkb/E9QDC4" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E9QDC4", "url": "https://www.uniprot.org/uniprotkb/E9QDC4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E9QDC4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QDC4" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 66, "end_pos": 93, "start_aa": "Phe", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JLP7-1", "uniprot_ac": "B8JLP7", "uniprot_id": "B8JLP7_DANRE", "mass": { "chemical_mass": 222440.0, "monoisotopic_mass": 222440.0 }, "refseq": { "ac": "NP_956444", "name": "ankyrin repeat domain-containing protein 12 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956444" }, "gene_names": [ { "name": "ankrd12", "type": "recommended", "evidence": [ { "id": "B8JLP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLP7" } ] }, { "name": "ankrd12", "type": "synonym", "evidence": [ { "id": "NP_956444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956444" } ] }, { "name": "fi16c02", "type": "synonym", "evidence": [ { "id": "NP_956444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956444" }, { "id": "B8JLP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLP7" } ] }, { "name": "wu:fi16c02", "type": "synonym", "evidence": [ { "id": "NP_956444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956444" }, { "id": "B8JLP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLP7" } ] }, { "name": "zgc:55925", "type": "synonym", "evidence": [ { "id": "NP_956444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956444" }, { "id": "B8JLP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLP7" } ] } ], "protein_names": [ { "name": "Ankyrin repeat domain-containing protein 12", "type": "synonym", "evidence": [ { "id": "B8JLP7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLP7/entry#names_and_taxonomy" } ] }, { "name": "ankyrin repeat domain-containing protein 12 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_956444", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956444" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01001068.1, SRR32588731.862727.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505388, SAMEA3505389 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Nov 26, 2025 this sequence version replaced NP_956444.2.", "evidence": [ { "database": "RefSeq", "id": "NP_956444", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956444" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JLP7", "url": "https://www.uniprot.org/uniprotkb/B8JLP7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ankrd12", "url": "https://www.uniprot.org/uniprotkb/B8JLP7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-040426-846", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-846", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "393119", "url": "https://www.ncbi.nlm.nih.gov/gene/393119", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:393119", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:393119", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0A8M6Z2V6", "url": "https://www.orthodb.org/?gene=A0A8M6Z2V6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "B8JLP7", "url": "https://www.orthodb.org/?gene=B8JLP7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24149", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24149", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24149:SF14", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24149:SF14", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12796", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12796", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_956444", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_956444", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2V6", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2V6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M6Z2V6-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M6Z2V6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JLP7", "url": "https://www.uniprot.org/uniprotkb/B8JLP7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JLP7-1", "url": "https://www.uniprot.org/uniprotkb/B8JLP7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-040426-846", "url": "https://zfin.org/ZDB-GENE-040426-846", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAKPGSDRDEAMVEKTAGKKSKEKISPFAKTPKLDRSELLGKEGKSKSSMKRKLSFTVSPSRNEERDSDADDSDPGQSSDAWGERLLPPCRIYADKDGPDKKKVKKESGGKKSTPVNILFGYPLSERKQMALVMQMTARDNSPDTTPNHPSQSPAVQKKIASSSTSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELIGLGADVNVKDFAGWTPLHEACNLGYYDVAKVLIGAGAEVNTQGLDDDTPLHDASSSGHKDIVKLLLRHGGNAFQANKRGERPVDVADSQELEQLLKGEIPLSEPEDSSSESEDPSSVNPSSVDENLEFSDAEKDSDCKSTTVKASSSMSGLDEYEFKDEEEEEDLSKSLNERHLFRRELRQKEKEEKDRNHYASKQGSKSDQSMLACKSKKTKASRVYCSSDSSSDEAEVQTERRSSPTRSVSVDGHKTDSRSKKESLTLTPVEQKEKGKQKKKNKSQSKNKENQEVREEGKENSKSLLFSSPTVSDNSDKGVREEDSFKMSFSAKDDTSVHLFHLSVVKSPKLNHSQTDKQATPLKQENAKTCVSIADGSCPGDGIKYNHYTDSDYCTEDSSSKSCKHKEKSKHHHKEPNLEGDDGSSSPFKDSSLSNSIDSSEGAFRKTDKDGKVVKKHKLKHKEKEKEKYRKEYEAERNRHRQKEPRKDGHRNLEFDREFWKENFFKSDENEEPVGKGEIPAGGSPVKSSDSSPVKEEKGASKDKHSTSSSNKDRRPKEERDKTIKKEKKEIPLKEERGKEDETDERTDGTFSVRIPDGSQHLSEEVDEKPATCNSADQEQLESPEKNSREKTDKRPPTKDRESEKSDKRHSDKDKKVKSEHLADKPELHNSTDRWKEKEKLTNVSYSPNDKSHKEGEKLKPMTPVKKHEENKKNKDKLDKKAEKEHASGDHRDKDKTTSEKKGKAPEKTADHGKSDRSKDKERDKDSDKRKKDKSTTPSSSSYSNLKSLLEEKKGYVCENNKVVSSKSKEEVTKPSEKDRDRRERDRESERHRDRERDRHKEKDKDRSQFNRDGKINKPKPSEVDSKSKVTPILKDTRPKEKRLVNDDLMKTSFERMLSLKDQEIEQWHKKHLEKIKQKERERLKQRPGIDPAKQQKNKEKIKSSSTSTEPCLTKELTRSKSSEAPDGQREKILKDATSVRTLSLDAKTLGKNGPIIENNLSRSPRPESEKSGLMSRSISMISVASSEDSCQATILTPRPTDQYDSDMNVEALDSQPPLLQSSLVAQSSRSPSVHDKDISSLPESSALCNRTPLASRHASPCLRAILDEEAKVPTTETKPTEESPVISIASQPTSEQSQVHLTEISVPPVQETRSSQSLTNSFPENEILSSNEAEVVSSTCQVQPSQASAKDSVTQANSVFPSHLEEQNKFCTTSSQIEHASLGQLDVPGAEGVKKEASLAVASLQSSHTSTSSSDSNAHLPSSSQHCEISSASSGEQTMTTDSSLRTEQRDKPLVASEDKIGEHVTKTDCASTPSPSTASCRSSSEESTKPLLKATSVQEDTEKGNEQVQEESISRFSNDPLVAVDAQPEKEEQGLHLASVTNVSCCASPERIPEEPMEVPEEVSDKSRITEIDEAKVLSSEEGAVTSSESKADSETPDPFSLDEKPLKSDILANVEQAQSSAPIHPDHQAEPTSGETSGSSSPISVMDRDSDISGARAKVRLLEEEADIQATHPRKRKMPRASPLAQANLTAQQVREKTQQSLAAIVDALKLEEIQPYQTERANPYYEYLHIRKKIEEKRKVLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKLCIPTITPPPSLPEPLKEMFKQQEMVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAEVYNMPQEVQGDDGKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQRLEWQLKLQELDPATYKSTSIFEIPEFYIPLVEVNDDFDLTPI", "length": 1987, "header": "tr|B8JLP7-1|B8JLP7_DANRE Isoform 1 of Ankyrin repeat domain-containing protein 12 OS=Danio rerio OX=7955 GN=ankrd12 PE=4 SV=1 CANONICAL=B8JLP7-1" }, "isoforms": [ { "isoform_ac": "A0A8M6Z2V6-1", "url": "https://www.uniprot.org/uniprotkb/B8JLP7/entry#A0A8M6Z2V6-1", "sequence": { "sequence": "MAKPGSDRDEAMVEKTAGKKSKEKISPFAKTPKLDRSELLGKEGKSKSSMKRKLSFTVSPSRNEERDSDADKDGPDKKKVKKESGGKKSTPVNILFGYPLSERKQMALVMQMTARDNSPDTTPNHPSQSPAVQKKIASSSTSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELIGLGADVNVKDFAGWTPLHEACNLGYYDVAKVLIGAGAEVNTQGLDDDTPLHDASSSGHKDIVKLLLRHGGNAFQANKRGERPVDVADSQELEQLLKGEIPLSEPEDSSSESEDPSSVNPSSVDENLEFSDAEKDSDCKSTTVKASSSMSGLDEYEFKDEEEEEDLSKSLNERHLFRRELRQKEKEEKDRNHYASKQGSKSDQSMLACKSKKTKASRVYCSSDSSSDEAEVPTERRSSPTRSVSVDGHKTDSRSKKESLTLTPVEQKEKGKQKKKNKSQSKNKENQEVREEGKENSKSLLFSSPTVSDNSDKGVREEDSFKMSFSAKDDTSVHLFHLSVVKSPKLNHSQTDKQATPLKQENAKTCVSIADGSCPGDGIKYNHYTDSDYCTEDSSSKSCKHKEKSKHHHKEPNLEGDDGSSSPFKDSSLSNSIDSSEGAFRKTDKDGKVVKKHKLKHKEKEKEKYRKEYEAERNRHRQKEPRKDGHRNLEFDREFWKENFFKSDENEEPVGKGEIPAGGSPVKSSDSSPVKEEKGASKDKHSTSSSNKDRRPKEERDKTIKKEKKEIPLKEERGKEDETDERTDGTFSVRIPDGSQHLSEEVDEKPATCNSADQEQLESPEKNSREKTDKRPPTKDRESEKSDKRHSDKDKKVKSEHLADKPELHNSTDRWKEKEKLTNVSHSPNDKSHKEGEKLKPMTPVKKHEENKKNKDKLDKKAEKEHASGDHRDKDKTTSEKKGKAPEKTADHGKSDRSKDKERDKDSDKRKKDKSTTPSSSSYSNLKSLLEEKKGYVCENNKVVSSKSKEEVTKPSEKDRDRRERDRESERHRDRERDRHKEKDKDRSQFNRDGKINKPKPSEVDSKSKVTPTLKDTRPKEKRLVNDDLMKTSFERMLSLKDQEIEQWHKKHLEKIKQKERERLKQRPGIDPAKQQKNKEKIKSSSTSTEPCLTKELTRSKSSEAPDGQREKILKDATSVRTLSLDAKTLGKNGPIIENNLSRSPRPESEKSGLMSRSISMISVASSEDSCQATILTPRPTDQYDSDMNVEALDSQPPLLQSSLVAQSSRSPSVHDKDSSSLPESSALCNRTPLASRHASPCLRAILDEEAKVPTTETKPTEESPVISIASQPTSEQSQVHLTEISVPPVQETRSSQSLTNSFPENEILSSNEAEVVSSTCQVQPSQASAKDSVTQANSVFPSHLEEQNKFCTTSSQIEHASLGQLDVPGAEGVKKEASLAVASLQSSHTSTSSSDSNAHLPSSSQHCEISSASSGEQTMTTDSSLRTEQRDKPLVASEDKIGENVTKTDCASTPSPSTASCRSSSEESTKSLLKATSVQEDTEKGNEQVQEESISRFSNDPLVAVDAQPEKEEQGLHLASVTNVSCCASPERIPEEPMEVPEEVSDKSRITEIDEAKVLSSEEGAVTSSESKADSEMPDPFSLDEKPLKSDILANVEQAQSSAPIHPDHQAEPTSGETSGSSSPISVMDRDSDISGARAKVRLLEEEADIQATHPRKRKMPRASPLAQANLTAQQVREKTQQSLAAIVDALKLEEIQPYQTERANPYYEYLHIRKKIEEKRKVLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKLCIPTITPPPSLPEPLKEMFKQQEMVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAEVYNMPQEVQGDDGKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQRLEWQLKLQELDPATYKSTSIFEIPEFYIPLVEVNDDFDLTPI", "length": 1963, "header": "tr|A0A8M6Z2V6-1|B8JLP7_DANRE Computationally mapped isoform of Ankyrin repeat domain-containing protein 12 OS=Danio rerio OX=7955 GN=ankrd12 PE=4 SV=2 CANONICAL=B8JLP7-1" }, "locus": {} }, { "isoform_ac": "B8JLP7-1", "url": "https://www.uniprot.org/uniprotkb/B8JLP7/entry#B8JLP7-1", "sequence": { "sequence": "MAKPGSDRDEAMVEKTAGKKSKEKISPFAKTPKLDRSELLGKEGKSKSSMKRKLSFTVSPSRNEERDSDADDSDPGQSSDAWGERLLPPCRIYADKDGPDKKKVKKESGGKKSTPVNILFGYPLSERKQMALVMQMTARDNSPDTTPNHPSQSPAVQKKIASSSTSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELIGLGADVNVKDFAGWTPLHEACNLGYYDVAKVLIGAGAEVNTQGLDDDTPLHDASSSGHKDIVKLLLRHGGNAFQANKRGERPVDVADSQELEQLLKGEIPLSEPEDSSSESEDPSSVNPSSVDENLEFSDAEKDSDCKSTTVKASSSMSGLDEYEFKDEEEEEDLSKSLNERHLFRRELRQKEKEEKDRNHYASKQGSKSDQSMLACKSKKTKASRVYCSSDSSSDEAEVQTERRSSPTRSVSVDGHKTDSRSKKESLTLTPVEQKEKGKQKKKNKSQSKNKENQEVREEGKENSKSLLFSSPTVSDNSDKGVREEDSFKMSFSAKDDTSVHLFHLSVVKSPKLNHSQTDKQATPLKQENAKTCVSIADGSCPGDGIKYNHYTDSDYCTEDSSSKSCKHKEKSKHHHKEPNLEGDDGSSSPFKDSSLSNSIDSSEGAFRKTDKDGKVVKKHKLKHKEKEKEKYRKEYEAERNRHRQKEPRKDGHRNLEFDREFWKENFFKSDENEEPVGKGEIPAGGSPVKSSDSSPVKEEKGASKDKHSTSSSNKDRRPKEERDKTIKKEKKEIPLKEERGKEDETDERTDGTFSVRIPDGSQHLSEEVDEKPATCNSADQEQLESPEKNSREKTDKRPPTKDRESEKSDKRHSDKDKKVKSEHLADKPELHNSTDRWKEKEKLTNVSYSPNDKSHKEGEKLKPMTPVKKHEENKKNKDKLDKKAEKEHASGDHRDKDKTTSEKKGKAPEKTADHGKSDRSKDKERDKDSDKRKKDKSTTPSSSSYSNLKSLLEEKKGYVCENNKVVSSKSKEEVTKPSEKDRDRRERDRESERHRDRERDRHKEKDKDRSQFNRDGKINKPKPSEVDSKSKVTPILKDTRPKEKRLVNDDLMKTSFERMLSLKDQEIEQWHKKHLEKIKQKERERLKQRPGIDPAKQQKNKEKIKSSSTSTEPCLTKELTRSKSSEAPDGQREKILKDATSVRTLSLDAKTLGKNGPIIENNLSRSPRPESEKSGLMSRSISMISVASSEDSCQATILTPRPTDQYDSDMNVEALDSQPPLLQSSLVAQSSRSPSVHDKDISSLPESSALCNRTPLASRHASPCLRAILDEEAKVPTTETKPTEESPVISIASQPTSEQSQVHLTEISVPPVQETRSSQSLTNSFPENEILSSNEAEVVSSTCQVQPSQASAKDSVTQANSVFPSHLEEQNKFCTTSSQIEHASLGQLDVPGAEGVKKEASLAVASLQSSHTSTSSSDSNAHLPSSSQHCEISSASSGEQTMTTDSSLRTEQRDKPLVASEDKIGEHVTKTDCASTPSPSTASCRSSSEESTKPLLKATSVQEDTEKGNEQVQEESISRFSNDPLVAVDAQPEKEEQGLHLASVTNVSCCASPERIPEEPMEVPEEVSDKSRITEIDEAKVLSSEEGAVTSSESKADSETPDPFSLDEKPLKSDILANVEQAQSSAPIHPDHQAEPTSGETSGSSSPISVMDRDSDISGARAKVRLLEEEADIQATHPRKRKMPRASPLAQANLTAQQVREKTQQSLAAIVDALKLEEIQPYQTERANPYYEYLHIRKKIEEKRKVLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKLCIPTITPPPSLPEPLKEMFKQQEMVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAEVYNMPQEVQGDDGKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQRLEWQLKLQELDPATYKSTSIFEIPEFYIPLVEVNDDFDLTPI", "length": 1987, "header": "tr|B8JLP7-1|B8JLP7_DANRE Isoform 1 of Ankyrin repeat domain-containing protein 12 OS=Danio rerio OX=7955 GN=ankrd12 PE=4 SV=1 CANONICAL=B8JLP7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JLP7", "url": "https://www.uniprot.org/uniprotkb/B8JLP7" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8JLP7", "url": "https://www.uniprot.org/uniprotkb/B8JLP7" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Analysis of a conditional gene trap reveals that tbx5a is required for heart regeneration in zebrafish.", "journal": "PLoS ONE", "date": "2018", "authors": "Grajevskaja Viktorija, Camerota Diana, Bellipanni Gianfranco, Balciuniene Jorune, Balciunas Darius", "evidence": [ { "database": "UniProtKB", "id": "B8JLP7", "url": "https://www.uniprot.org/uniprotkb/B8JLP7" } ], "reference": [ { "type": "PubMed", "id": "29933372", "url": "https://glygen.org/publication/PubMed/29933372" } ] }, { "title": "Analyses of mRNA structure dynamics identify embryonic gene regulatory programs.", "journal": "Nat. Struct. Mol. Biol.", "date": "2018", "authors": "Beaudoin Jean-Denis, Novoa Eva Maria, Vejnar Charles E, Yartseva Valeria, Takacs Carter M, Kellis Manolis, Giraldez Antonio J", "evidence": [ { "database": "UniProtKB", "id": "B8JLP7", "url": "https://www.uniprot.org/uniprotkb/B8JLP7" } ], "reference": [ { "type": "PubMed", "id": "30061596", "url": "https://glygen.org/publication/PubMed/30061596" } ] }, { "title": "4.1Ba is necessary for glutamatergic synapse formation in the sensorimotor circuit of developing zebrafish.", "journal": "PLoS ONE", "date": "2018", "authors": "Fierro Javier, Haynes Dylan R, Washbourne Philip", "evidence": [ { "database": "UniProtKB", "id": "B8JLP7", "url": "https://www.uniprot.org/uniprotkb/B8JLP7" } ], "reference": [ { "type": "PubMed", "id": "30286167", "url": "https://glygen.org/publication/PubMed/30286167" } ] } ], "pathway": [ { "id": "dre:393119", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:393119", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XAC9-1", "protein_name": "Ankyrin repeat domain 12", "gene_name": "ANKRD12", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPKSGSTKTAQIENSDSDSTMVEKPAARKSKDKIASYSKSPKVDRSDVGKEMKEKSSMKRKLPFTISPSRNEDRNSDTEKEGPEKKKVKKDAGNKKSTPVSILFGYPLSERKQMALLMQMTARDNSPDSNLNHPLQTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKVLIAAGADVNTQGLDDDTPLHDSASSGHRNIVKLLLRHGGNPFQANKHGERPVDVAETEELEMLLKREVPISDDEDSCSDSEEAPSVNPSSVEGNVDSEVEKDSVANGSKQIVHSKAPHPPALDEYEFKDDDEDEMKKMIDDRHILRKDVRKEDETEVEKNSLFAKQDKVSYSKSLKNKKQKPSRVLYSSSESSDEEIVQDKKIVSPCSVSETSSSDVRAKKECVVTNEHKQKGKVKKKVKNQSKNKENQELKQEKENARVTNIAASGLDSLDKTRDEETFKKSFSQKDDSSLQLFHIAAGKSPKHPCGLSEKQATALKQENTKTCLSPGGSEITLQPELVRCDHSVDSEYLVESSSGKSCKHKEKSKHHQKDFQLEFGEKSSPKIKDEDNSSTFENSEYTLRKIDKEGKALKKHKLKHKEREKDKDKKEQDGEKEKHKHNIKESQRSIEFDREFWKENFFKSDDSEDTLLNTEHETLPSDRKSKLEKAVAKEDRLAKERQFHKERNAREEREKNKKENEKFLKDEKMKDSKEEKETILADKEMEMFCLSVKDEVISMHLIEKEADTEKHEKNLKENKEKRTSAKEKDVEKAERKNGEKEKKIKHECKTEKAEVNENMEKVKEKTNFQQAERCHKENDKIKSTGALKKLDEKEKNKEKMEKKHDKEKVDKDRHLADSKEKHCIERKVKQSEKESEYTKSEKNRTKDKEKEPERRDKSKDKETSTVVNSKHVQEERRCNIADSNKSMHDKLTSLKEKQKDDFLKTPDGREKDKKDKDIDRYKERDKHKQHQSSLLKLKLEHEKLKPKTSPAPKDARPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHRKHKEKIKQKEKERLRNRTCLELSKIKEKQRQSLPEVKNKELTRSKSSELPDFCMKEKQQKEATSSRSQSVDTRNVNVIKSLLVLDNANKSPKSEGEKMGLSSKSVSIISVASSEDSCHTTVTTPRPAMECDSDFVLEGADSQMSFSQSPFLPTAKSPALLERETDGVAELSDRMKPSFANRLPPAYIRSASFEDFKLVLNECRPVVEVRRCSMPASVSEHSKPPRISEENNQNAQMSVQTYPSTSPKPELPCSMVERDIQSSFSGLRSSPTRAVSNKQVTMGTNTIKNTAQMSPSEECNIHLEPCSQSGVTQQTKPWDVPFDRLNSINNECSSSGYDVSEQDTNNFVAMHNSETRTIKEQKVAEYLPQPAEIKGNSSSQESASFLPSQSPCSLPIQPLPEGSKHISSPGISNQDSLPVQQNLVQTVSSAFNTDASSTRETENVFIPSNIKKADAPHAIYSEGSAKDISEICERVNDLPVVVLERDIPESDGTSQLNVNSYVFNKLVCKNTQIEVDGNTVDTSNFRNEKDQQENLISVHVVNSKADTDLCDLRSAMSQGIMNNSSNKKPCTADGEDVLTDEAPQYSLSNSENNSQEIIQEEVHKYSQIVKLEEIAEDQKMEQQEVPQRITRNRANVLANQGKQNPVVCMQTLEKESELLASMKGRIRLTEDDDGQVHHPRKRKVSRVPQPVQVNPSLLQAKEKTQQSLAAVVDSLKLEEIQPYCSERANPYFEYLHIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLKELFKQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAEVYNVPLDAQADDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQRLEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI", "length": 2015 }, "evidence": [ { "id": "B8JLP7", "url": "https://omabrowser.org/oma/group/B8JLP7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZCH1-1", "protein_name": "Ankyrin repeat domain 12", "gene_name": "Ankrd12", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKSGFTKPVQSENSDSDSSMVERPYGRKSKDKIASYSKTSKIDRGDMGKEIREKSSMKRKLPFTLSPSRNEERDSDTDSDPGHTSENWGERLISSYRTYSEKEGPEKKKTRKEAGTKKSTPVSILFGYPLSERKQMALLMQMTARDNSPDSTPSHPSQATPAQKKTPSSSSRQKDKINKRNERGETPLHMAAIRGDVKQVKELISLGADVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKREVPLSGDDESYTDSEEAQSVNPSSVDENIDSETEKDSFVCGSQSLPSKAPLPSALDEYEFKDDDGEEISKMIDGRHILRREQRKENESEAERSGLFAKQEKPFYSKSFKTKKQKPSRVLYSSTESSDEEVLQNRKISTACSVAETSHSDVQAKREYEYKQKGKVKRKLKNQNKNKENQELKQEKEGKENSRIANLAVNTALDCSERNREDGAFRRSFSPKDDASLHLLHMPTGKSPKHPCGLSEKQATPLKQDHMKTCISPGSSETSLQPELSRYENAEPEFLPESSNVKPYKHKEKNKHQKDFHLEFGEKSNAKIKDEDHSAAFENSDCTLKKMDKEGKTLKKHKLKHKERDKEKHRKEAEGEKEKYKSRDNAKEPQRSIEFDREFWKENFFKSDETEDLFLNMEHESLTEKKSKVEKTVKDDRLAKDKHASKERNCKEEREKTKRENEKSLKEERLKDPKEEKDGVSAEKEAEGSSMAVSANQETSGPHSSEREVDIEKQERHSKEREKSDRRFQTKEKELDRTERKVSEKEKKLKHEHKSEREKLDFSDCTDRVKEKDRLYSPQTERCHKEGEKMRNTVRKAEDRERAREKTDRKHDREKPERERCLAESKEKYLEKRKQSDNSEYSKSEKVRNRDRDREGEKKEKLRDKESVNVANLRHLQEERKSSTGEGSSKTQHEKALSLKERVRDEPLKIPDGKEKDKKDIDRYKERDKRKEKAQLSTLIRLKSETEKLKPKLSPASKDARPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRSCLELKVKDKEKTKHTPSESKNKELTRSRSSELTDVYNKEKQSKDVGSNRSQSVDNKSVLSLGKLPYVSENSSSRSPRSEGEKLGLSSRSVSMLSVASSEDSCHTVTTPRPLVEYDSDFMLEGSESQLSFSQSPFLPNAKSPALYERELESLAELPERLKPPYANRLPVCHLRSSSVEDVKLITNEVRPAVEIRRCSMPSVICEPIKHFQVSEDSSQGNLAVPRETSLSPRPEVSLVPERGLSHVSDLHPRCTDSPVRSVDSSSVSSDVHVIKSAALVGTLIDTSMHLETSNQVGVIQSKSWETPVDKLESLSTNDFICPDSSTSDQDSSAQSFYHSENKMLREQNADCLPVHQTELPGNSCAQDPASFTLSSPQPCSFTNQSLSDAESLPKPVSLSYGASQEPGVLQQRSAAHMISSVLESDNNFTKEVESSFVLADIQKTNSFVPAYSESTVQETLPNFEKANTLLVLPSEKDFSGSDAASQLNTHYAFSKLTYKSSSSHEIEKGPDDTQVISHEKENKLQSLVLTPLSKCDSDLYEVNAGMPKGNLNEQDNPKHGPDSEKDSLSTEDEESQQSTLSSVENHSQQSAQPEIQKYDQMVKGELEENAEDDKTENQTPQRMTRNKASALVSQSKQVLAGCTLLPEKDNDSSPRGRIRLTEEDDPQIHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAALVDSLKLDEIEPYSSERANPYFEYLHIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLKELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAEVYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQRLEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI", "length": 2047 }, "evidence": [ { "id": "HGNC:29135", "url": "https://alliancegenome.org/gene/HGNC:29135#orthology", "database": "AGR" }, { "id": "MGI:1914357", "url": "https://alliancegenome.org/gene/MGI:1914357#orthology", "database": "AGR" }, { "id": "B8JLP7", "url": "https://omabrowser.org/oma/group/B8JLP7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BKN6-1", "protein_name": "Ankyrin repeat domain 12", "gene_name": "ANKRD12", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKSGFTKPVQSENSDSDSNMVEKPYGRKSKDKIASYSKTPKIDRNDVGKEMKEKSSMKRKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRTCSEKEGPEKKKTKKEAGNKKSTPVSILFGYPLSERKQMALLMQMTARDNSPDSTPNHPSQTPPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKREVPLSDDDESYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQIVPSKAPLPSALDEYEFKDDDEEEINKMIDDRHILRKELRKENESEVEKSSLFAKQEKTFYPKSFKSKKQKPSRVLYSSSESSDEEILQNKKCSAPCSVPETSNSDIQTKKEYGVSNEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRVTNLTVNTALDCSDKTRDEGNFRKSFSPKDDTSLHLFHISSGKSPKHSCGLSEKQSTPLKQEHSKTCLSPGSSEMSLQPDLVRYDNIESEFLPESSSVKSCKHKEKNKHHKDFHLEFGEKSNAKIKDDDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKSRDGTKELQRSVEFDREFWKENFFKSDETEDLFLSMEHESLTLEKKSKLEKNIKDDKSTKEKHISKERNFKEEREKIKKESEKSFREEKIKDLKDDRENVLTDKETEFSSLGVSATEETIGLHSVEKEIEIEKHMKESKEKSEKRFQTKDKDIERADRKNSEKEKKIKHEHKSEKDRLDPSECVDRIKEKDKLYSHHTEKCHREGEKLKNITTIKKNDDRDKSREKMDRKHDKEKPEKERHPVESKEKHLMEKKNKPSDNSDYTKSEKSKNKEKDREVDKKDKSRDSVNISNSKHFQEERKSSITDSNKAQHEKTLSLKEKTKDEPLRTPDGKEKDKKDIDRYKERDKHKDKILSSSLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHRKHKEKIKQKEKERLRNRSCLELKVKDKEKTKHALAESKNKELTRSKSSELTDTYIKEKHCKDAVSNRSQSVDTKNTMSLGKSSFVSDNSLNRSPRSESEKPGLSSRSVSLISVASSEDSCLTTMTTPRPPVEYDSDFMLEGSDSQMSFSQSPFLPVAKSPALHDRELDSLTDLSERIKASYASRLLTSHLRASSVEDAKLVTNEGRSAAEARRCSMPSVICEHTKQFQTISEEGSQDGSAVPREICPSPKSEVSSNVPERELLSVSNIHSSFAASPTRSINSKYNSTDTNVIKGTAPLGMLMGSPVHLESSNQVGVIQSKSWEMESLNTGDFSCPNSAAPDQDSSVQGFCNPENKVLREQNIDFVSMHQTELPANTCAQDPASVLPSQQPCSSHSQSLSDAESIPRHTSLSYVTTQEPGILQQKNAIQMISSVLDTDTEPTKDMENTFVLTDVQKTDAFVPVYSESTVEEAAPNFEKASTLPVLPSEKDFNGSDGSSQPNPHYAFSKLMFKSSSGHEAEKSTSDTQDTSHEKENKLESLVLTHLNDKCDSDLCEMNVGVPKGNLSEPDNPKHCPESEKCLLSIEDEESQQSTLSSLENHPQPSAPPEMHKYGHLVKVELEESAEDDKPESQIPQRMTRNKGNTGASQSKQLLASCALLPDKDSESASPRGRIRLTEEDDPQIHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYLHIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLKELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAEVYSVPLDAQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQRLEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI", "length": 2050 }, "evidence": [ { "id": "B8JLP7", "url": "https://omabrowser.org/oma/group/B8JLP7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "G3HZ26-1", "protein_name": "Ankyrin repeat domain-containing protein 12 isoform X1", "gene_name": "Ankrd12", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPRSGFPKPVQSENSDSDSNMVERPYGRKSKDKIASYSKTSKIDRGDIGKEMKEKPSMKRKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRTYSEKEGPEKKKTKKEAGSKKSTPVSILFGYPLSERKQMALVMQMTARDNSPDSTPSHPSQATPAQKKTPSSSSRQKDKINKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKREVPLSGDDESYTDSEEAHSVNPSSVDENIDSEPEKDPFICESKVLPSKAPLPSALDEYEFKDDDEEEIGRMIDDRHILRKEQRKESELEAEKSGLFAKQEKAFYCKSFKAKKQKPSRVLYSSTDSSDEDLLQGSKRASTTCSVPETSSADTQARREYEYKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTALDCSEKTREEGNFRKSFSPKDDTSLHLFHISTGKSPKHACGLSEKQSTPLKQEHTKACISPGSSEMSLQPDLARYDTTEPEFLPENTNLKSYKHKEKSKHQKDFHLEFGEKSNAKMKDEDHNPTFENSECTLKKMDKEGKTLKKHKLKHKEREKEKHRKEADSEKEKYRNKGNPEELQRGIEFDREFWKENFFKSDETEDLFLNMEHESLTEKKSKLEKNMKDDKSTKEKHVSKERSFKEEREKTKKESEKSLREEKLKEDRDSMSTEKDVECGSVGIALNQESVGPHSAEKEMDIEKQEKHTREREKSDRRFQTKEKEVEKTERKFSEKEKKMRHEHKSEKEKWDFSENVDRIKEKDKLWSQQTERCQKEGEKTKNTVKKTDDRERNREKVDRKHDKERPEKERCLAESKEKHLEKKKCDNSEYTKSEKARNKDREGEKKEKFRDKESINITNSRHLQEEKRSSIGDSSSKIQHEKTVSLKEKARDEPLKTPDGKEKDKKDIDRYKERDKRKDKIQLNTLIKLKSETDKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRTCLELKVKDKDKTKHTPTESKSKEFARSRSSELTDAYNKEKQSKDAGSNRSQCVDSKNVLNLGKSPFIPENSSNRSPRSESERLGLSSRSVSMISVASSEDSCHTVTTPRPPVEYDSDFMLEGSESQLSFSQSPFLPNAKSPALYERELESLADLPERLKAPCTNRVPVCHLRSSSVEDVKVIPSEARPAVEIRRCSMPSVICEPTKHFQIPEESAQGSLAVPRETCPSPKPEVSSAVPERGLPHVSEFHPNLAGSPTRSVNSRYISSDTNVIKSVSLVGTLMDSPMNLEPSNQVGVIQNKSWEMPAEKLESLSTNDLICPDPSTSDQDSSAQSFCHSENKTLREQNTDCLSSPQTEMPGKSCAQDAASLLSSLQPCSFSNQAHSDAESASKAVSLSCGASQEPGVLQERNAGHVISSVLDSDNNFTKEMENAFVLADIQKTNSFVPVYSESTVQETLASFEKASTLLVLPSGKDFSGSDGASQMSTQYTFSKLTYKSSSSHQVEKSIDDTQVTSHEKEKRLQGLVLTQLSKCDSDLYGMDAGMPKGSLSDQDPAKHSPGSEKYLLPIEDEESQQSPLSSVESHSQPSAQPELHKYDQLTKGDLEESAEDDKTENQHPQRLTRNKVSPVVSQSKQILAGCTLLPEKDSDSSPRGRIRLTEDDDPQIHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYLHIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLKELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAEVYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQRLEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI", "length": 2042 }, "evidence": [ { "id": "B8JLP7", "url": "https://omabrowser.org/oma/group/B8JLP7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G5E893-1", "protein_name": "Ankyrin repeat domain 12", "gene_name": "Ankrd12", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKSGFTKPVQSENSDSDSSMVERPYGRKSKDKIASYSKTSKIDRGDMGKEMREKPSMKRKLPFTVSPSRNEERDSDTDSDPGHTSENWGERLISSYRTYSEKEGPEKKKTKKEAGTKKSTPVSILFGYPLSERKQMALLMQMTARDNSPDSTPSHPSQATPAQKKTPSSSSRQKDKINKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKREVPLSGDDESYTDSEEAQSVNPSSVDENIDSETEKDSFVCGSKILPSKAPLPSALDEYEFKDDDEEEISKMIDDRHILRKEQRRENESEAERSGLFAKQEKTFYSKSFKTKKQKPSRVLCSSTESSDEEGLQNRKISTACSVAESSHPDMQAKKEYEYKQKGKVKRKLKNQNKNKENQELKQEKEGKENSRIATLTVNTALDCSEKYREEGNFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQTPLKQEHTKACISPGSSEMSLQPDLTRYDNAEPESSNVKSYKHKEKNKQQKDFHIEFGEKSNAKIKDEDHNPAFENSDCTLKKMDKEGKTLKKHKLKHKEKDKEKHKKEVEGEKEKYKNKDNAKELQRSIEFDREFWKENFFKSDETEDLFLTMEHESIIEKKTKMEKNMKDDRSAKEKHVSKERNFKEEREKTKKENEKSLREEKVKDPKEEKDSVSTEKEAECCSVGVSVSQEAAGLHSSEKEMDAEKQERHTKEREKSDRRFQTKEKELDRNERKFSEKEKKIKHEHKSEREKLDFSDCTDRVREKDKLYSHQTERCHKDSEKLKNTVRKTDDRERNREKADRKHDREKPERERYLAENKEKHLEKRKQSDSSEYSKSEKVRTKDRDREGEKKEKLRDKESVNVTNLKHLQEERKSSTGDSSGKTQHEKALSLKERARDEPLKTPDGKEKDKKDIDRYKERDKRKDKAQLNTLIRLKSETEKLKPKLSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHRKHKEKIKQKEKERLRNRTCLELKVKDKEKTKHAPTESKSKELTRSRSSELTDVYSKEKQSKDVGSNRSQSVDNRNVLNLGKPSYISESGSNRSPRSEGERLGLSSRSVSMLSVASSEDSCHTVTTPRPLVEYDSDFMLEGSESQLSFSQSPFLPNAKSPALYERELEGLTELPDRLKPPYTNRLPVCHLRSSSVEDVKLITNEVRPAVEIRRCSMPSVICEPIKHFQVSEESSQGNLAVPRETCLSPKPEVSSAVPERGLSHVSDLHPNCTGSPTRSANSSYISSDVNVIKSATLVGTLIDSSMHLEPSNQVGVIPSKSWETPVDKLESLSTNDFICPDSNISDQDSSAQSFYNSENKMLREQNTDCLPPHQPELPGNSCAQDPASFLSSPQPCSFSNQPLAGADSVPKPVSLSYVVSQEPGVLQQKSAAQMASSVLDSDNNFPEDVENTFVLADIQKTNSFLPAYSESTVQEALPSFEKANTLLVLPSEKDFNGSDTAQPNTHYAFSKLTYKSSNSQEIEKGPDDTQIISHEKENKLQSLVLTQLSKCDSDLYEMNAGLPKGNLNEQDNPKHGLDSEKYSLSTEDEESQQSTLSSVENHSQQSAQPEMHKYDQLSKVELEENAEDDKTENQTPQRVTRNKASTVVNPSKPMLAGCALVAEKDNESSPRGRIRLTEEDDPQIHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIEPYSSERANPYFEYLHIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLKELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAEVYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQRLEWQLKLQELDPATYKSLSIYEIQEFYVPLVDVNDDFELTPI", "length": 2041 }, "evidence": [ { "id": "HGNC:29135", "url": "https://alliancegenome.org/gene/HGNC:29135#orthology", "database": "AGR" }, { "id": "MGI:1914357", "url": "https://alliancegenome.org/gene/MGI:1914357#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-846", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-846#orthology", "database": "AGR" }, { "id": "B8JLP7", "url": "https://omabrowser.org/oma/group/B8JLP7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6UB98-1", "protein_name": "Ankyrin repeat domain-containing protein 12", "gene_name": "ANKRD12", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKSGFTKPIQSENSDSDSNMVEKPYGRKSKDKIASYSKTPKIERSDVSKEMKEKSSMKRKLPFTISPSRNEERDSDTDSDPGHTSENWGERLISSYRTYSEKEGPEKKKTKKEAGNKKSTPVSILFGYPLSERKQMALLMQMTARDNSPDSTPNHPSQTTPAQKKTPSSSSRQKDKVNKRNERGETPLHMAAIRGDVKQVKELISLGANVNVKDFAGWTPLHEACNVGYYDVAKILIAAGADVNTQGLDDDTPLHDSASSGHRDIVKLLLRHGGNPFQANKHGERPVDVAETEELELLLKREVPLSDDDESYTDSEEAQSVNPSSVDENIDSETEKDSLICESKQILPSKTPLPSALDEYEFKDDDDEEINKMIDDRHILRKEQRKENEPEAEKTHLFAKQEKAFYPKSFKSKKQKPSRVLYSSTESSDEEALQNKKISTSCSVIPETSNSDMQTKKEYVVSGEHKQKGKVKRKLKNQNKNKENQELKQEKEGKENTRITNLTVNTGLDCSEKTREEGNFRKSFSPKDDTSLHLFHISTGKSPKHSCGLSEKQSTPLKQEHTKTCLSPGSSEMSLQPDLVRYDNTESEFLPESSSVKSCKHKEKSKHQKDFHLEFGEKSNAKIKDEDHSPTFENSDCTLKKMDKEGKTLKKHKLKHKEREKEKHKKEIEGEKEKYKTKDSAKELQRSVEFDREFWKENFFKSDETEDLFLNMEHESLTLEKKSKLEKNIKDDKSTKEKHVSKERNFKEERDKIKKESEKSFREEKIKDLKEERENIPTDKDSEFTSLGMSAIEESIGLHLVEKEIDIEKQEKHIKESKEKPEKRSQIKEKDIEKMERKTFEKEKKIKHEHKSEKDKLDLSECVDKIKEKDKLYSHHTEKCHKEGEKSKNTAAIKKTDDREKSREKMDRKHDKEKPEKERHLAESKEKHLMEKKNKQSDNSEYSKSEKGKNKEKDRELDKKEKSRDKESINITNSKHIQEEKKSSIVDGNKAQHEKPLSLKEKTKDEPLKTPDGKEKDKKDKDIDRYKERDKHKDKIQINSLLKLKSEADKPKPKSSPASKDTRPKEKRLVNDDLMQTSFERMLSLKDLEIEQWHKKHKEKIKQKEKERLRNRNCLELKIKDKEKTKHTPTESKNKELTRSKSSEVTDAYTKEKQPKDAVSNRSQSVDTKNVMTLGKSSFVSDNSLNRSPRSENEKPGLSSRSVSMISVASSEDSCHTTVTTPRPPVEYDSDFMLESSESQMSFSQSPFLSIAKSPALHERELDSLADLPERIKPPYANRLSTSHLRSSSVEDVKLIISEGRPTIEVRRCSMPSVICEHTKQFQTISEESNQGSLLTVPGDTSPSPKPEVFSNVPERDLSNVSNIHSSFATSPTGASNSKYVSADRNLIKNTAPVNTVMDSPVHLEPSSQVGVIQNKSWEMPVDRLETLSTRDFICPNSNIPDQESSLQSFCNSENKVLKENADFLSLRQTELPGNSCAQDPASFMPPQQPCSFPSQSLSDAESISKHMSLSYVANQEPGILQQKNAVQIISSALDTDNESTKDTENTFVLGDVQKTDAFVPVYSDSTIQEASPNFEKAYTLPVLPSEKDFNGSDASTQLNTHYAFSKLTYKSSSGHEVENSTTDTQVISHEKENKLESLVLTHLSRCDSDLCEMNAGMPKGNLNEQDPKHCPESEKCLLSIEDEESQQSILSSLENHSQQSTQPEMHKYGQLVKVELEENAEDDKTENQIPQRMTRNKANTMANQSKQILASCTLLSEKDSESSSPRGRIRLTEDDDPQIHHPRKRKVSRVPQPVQVSPSLLQAKEKTQQSLAAIVDSLKLDEIQPYSSERANPYFEYLHIRKKIEEKRKLLCSVIPQAPQYYDEYVTFNGSYLLDGNPLSKICIPTITPPPSLSDPLKELFRQQEVVRMKLRLQHSIEREKLIVSNEQEVLRVHYRAARTLANQTLPFSACTVLLDAEVYNVPLDSQSDDSKTSVRDRFNARQFMSWLQDVDDKFDKLKTCLLMRQQHEAAALNAVQRLEWQLKLQELDPATYKSISIYEIQEFYVPLVDVNDDFELTPI", "length": 2062 }, "evidence": [ { "id": "HGNC:29135", "url": "https://alliancegenome.org/gene/HGNC:29135#orthology", "database": "AGR" }, { "id": "MGI:1914357", "url": "https://alliancegenome.org/gene/MGI:1914357#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-040426-846", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-040426-846#orthology", "database": "AGR" }, { "id": "B8JLP7", "url": "https://omabrowser.org/oma/group/B8JLP7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8IQI3-1", "protein_name": "Ankyrin repeat domain-containing protein 12", "gene_name": "Ankrd11", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPPRPKGIGFNTGATQPRSNSNTPMSERQQMALLIQMTANSSTVQSQSLELLLVGLNFNLHHSSRTTLKKNECKKGDAETDEGSLNEKQEVLDTKDKSSAEESSNDGKSSDTNHQGTSAAKRCYSDIEEDYEESGEDVKKKKRKDSEHGKDVKGASLKLTSRVEKSSKLAATKGSPSGNKSSASNAEKEPAETSKNVDIENETECSDDYKSNDSLYNGGLKVPPLKIVIPQQNCSIDTEGNVLRTGKVTASRNAALPYVVSSNSDSIDTVITNQSISPHESPQKSNSICSTALDDKNIKLFNDEKNLRVLRSSHRTGVTSVERSSNNSSPQMQSSSPSPASSNHANDPADVKLSYSNMTSSPIPQGHQFDQEAITNVPSPSTSSTSSSKDINPSNVELHPRKRKIRPKNTDDSSKNSNAADSGVNSEESHPHDHPFTNGFQMFLSIRRQIEKKWKSLYPVKPRPPQGYNEYLLTKKSYLLRRNATISVPDIPRTVPQAMERIYQDQEKARRDLIEAHTVEREKLCMNVEQEIIRVHSKAARSISGQPAPYSVCTYLKDDEVYNMITPEQDEKEKSARCRFNGRLLLSWLQDVDDKWEKIKESMVLRHHNEAESLHAVQVMDWNIFAKRNRLCDNPIEVNLEHVPIVSVGDDFDTLPT", "length": 658 }, "evidence": [ { "id": "HGNC:29135", "url": "https://alliancegenome.org/gene/HGNC:29135#orthology", "database": "AGR" }, { "id": "MGI:1914357", "url": "https://alliancegenome.org/gene/MGI:1914357#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleoplasm", "id": "GO:0005654", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005654", "evidence": [ { "database": "UniProtKB", "id": "B8JLP7", "url": "https://www.uniprot.org/uniprotkb/B8JLP7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1193, "end_pos": 1195, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1283, "end_pos": 1285, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1577, "end_pos": 1579, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1724, "end_pos": 1726, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1796, "end_pos": 1798, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1870, "end_pos": 1872, "annotation": "n_glycosylation_sequon" }, { "start_pos": 474, "end_pos": 476, "annotation": "n_glycosylation_sequon" }, { "start_pos": 544, "end_pos": 546, "annotation": "n_glycosylation_sequon" }, { "start_pos": 863, "end_pos": 865, "annotation": "n_glycosylation_sequon" }, { "start_pos": 876, "end_pos": 878, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1193, "end_pos": 1195 }, { "start_pos": 1283, "end_pos": 1285 }, { "start_pos": 1577, "end_pos": 1579 }, { "start_pos": 1724, "end_pos": 1726 }, { "start_pos": 1796, "end_pos": 1798 }, { "start_pos": 1870, "end_pos": 1872 }, { "start_pos": 474, "end_pos": 476 }, { "start_pos": 544, "end_pos": 546 }, { "start_pos": 863, "end_pos": 865 }, { "start_pos": 876, "end_pos": 878 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7FH60-1", "uniprot_ac": "E7FH60", "uniprot_id": "E7FH60_DANRE", "mass": { "chemical_mass": 30576.0, "monoisotopic_mass": 30576.0 }, "refseq": { "ac": "NP_001373488", "name": "protein cholesin isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373488" }, "gene_names": [ { "name": "chlsn", "type": "recommended", "evidence": [ { "id": "E7FH60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FH60" } ] }, { "name": "c24h7orf50", "type": "synonym", "evidence": [ { "id": "NP_001373488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373488" }, { "id": "E7FH60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FH60" } ] }, { "name": "chlsn", "type": "synonym", "evidence": [ { "id": "NP_001373488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373488" } ] }, { "name": "zmp:0000000624", "type": "synonym", "evidence": [ { "id": "NP_001373488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373488" }, { "id": "E7FH60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FH60" } ] } ], "protein_names": [ { "name": "Uncharacterized protein C7orf50 homolog", "type": "synonym", "evidence": [ { "id": "E7FH60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FH60/entry#names_and_taxonomy" } ] }, { "name": "chromosome 24 C7orf50 homolog", "type": "synonym", "evidence": [ { "id": "NP_001373488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373488" } ] }, { "name": "protein cholesin isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001373488", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373488" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH590666.1, SRR32588726.4874424.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505372 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Dec 1, 2025 this sequence version replaced NP_001373488.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001373488", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373488" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FH60", "url": "https://www.uniprot.org/uniprotkb/E7FH60" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "chlsn", "url": "https://www.uniprot.org/uniprotkb/E7FH60", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-627", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-627", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "567594", "url": "https://www.ncbi.nlm.nih.gov/gene/567594", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019327", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019327", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567594", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567594", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7FH60", "url": "https://www.orthodb.org/?gene=E7FH60", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22306", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22306", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22306:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22306:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10180", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10180", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001373488", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373488", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PGL4", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGL4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PGL4-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PGL4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FH60", "url": "https://www.uniprot.org/uniprotkb/E7FH60", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FH60-1", "url": "https://www.uniprot.org/uniprotkb/E7FH60-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-627", "url": "https://zfin.org/ZDB-GENE-130530-627", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDKSKADEPLKKKKVKSAQKEKTNKRKAEDEDLVTLQEDETNRNVTEEKTEKKQKKRKKSKTEDLVTLQEDETNTNIPEEKTEKQQKKRKKSKTKSSEIMKQQEPSVKEEEQEENGPGEEEELSPEERRVLERKLKKIRKKEEKKKLKEESKSVTPENNVAEKQALEYLTCWSERREEWKFQKTRQTWLLQNMYDSVKVPDSHFDVLLSYLDGLRGSARDTTLQKAEVILRWDGQGEKEETQDAEKKQQRAKQIVQLL", "length": 258, "header": "tr|E7FH60-1|E7FH60_DANRE Isoform 1 of Uncharacterized protein C7orf50 homolog OS=Danio rerio OX=7955 GN=chlsn PE=1 SV=1 CANONICAL=E7FH60-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PGL4-1", "url": "https://www.uniprot.org/uniprotkb/E7FH60/entry#A0A8M9PGL4-1", "sequence": { "sequence": "MDKSKADEPLKKKKVKSAQKEKTNKRKAEDEEDETNRNITEEKTEKKQKRRKKSKAEDLVTLQEDETNTNNSEEKTEKQQKKRKKSKTKSSEIMKQQEPSVKEEQQEENGPGEEEELSPEERRVLERKLKKIRKKEEKKKLKEESKSVTPENNVAEKQALEYLTCWSERREEWKFQKTRQTWLLQNMYDSVKVPDSHFDVLLSYLDGLRGSARDTTLQKAEVILRWDGQGEKEDTKDAEKKQQRAKQIVQLL", "length": 252, "header": "tr|A0A8M9PGL4-1|E7FH60_DANRE Computationally mapped isoform of Uncharacterized protein C7orf50 homolog OS=Danio rerio OX=7955 GN=chlsn PE=1 SV=2 CANONICAL=E7FH60-1" }, "locus": {} }, { "isoform_ac": "E7FH60-1", "url": "https://www.uniprot.org/uniprotkb/E7FH60/entry#E7FH60-1", "sequence": { "sequence": "MDKSKADEPLKKKKVKSAQKEKTNKRKAEDEDLVTLQEDETNRNVTEEKTEKKQKKRKKSKTEDLVTLQEDETNTNIPEEKTEKQQKKRKKSKTKSSEIMKQQEPSVKEEEQEENGPGEEEELSPEERRVLERKLKKIRKKEEKKKLKEESKSVTPENNVAEKQALEYLTCWSERREEWKFQKTRQTWLLQNMYDSVKVPDSHFDVLLSYLDGLRGSARDTTLQKAEVILRWDGQGEKEETQDAEKKQQRAKQIVQLL", "length": 258, "header": "tr|E7FH60-1|E7FH60_DANRE Isoform 1 of Uncharacterized protein C7orf50 homolog OS=Danio rerio OX=7955 GN=chlsn PE=1 SV=1 CANONICAL=E7FH60-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7FH60", "url": "https://www.uniprot.org/uniprotkb/E7FH60" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:567594", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567594", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q5I0E3-1", "protein_name": "Cholesin", "gene_name": "Chlsn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVKQKRKGLERTAKESKKQKITPAEETPRASEARPGKEAASPVVQEASPELSPEERRVLERKLKKERKKEEKKRLREAGIATAQTAKVQTPPAKPSAAVLALEYLQGWAEKQESWRFQKTRQTWLLLHMYDEDKVPEQHFSTLLDYLEGLRGSARELTVQKAETLMQELDGTDPKARSLGKMQRLRQVLQLLS", "length": 193 }, "evidence": [ { "id": "E7FH60", "url": "https://omabrowser.org/oma/group/E7FH60/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BRJ6-1", "protein_name": "Protein cholesin", "gene_name": "CHLSN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAKQKRKVPEVTEKKNKKLKKASAEGPLLGPEAAPSGEGAGSKGEAVLRPGLDAEPELSPEEQRVLERKLKKERKKEERQRLREAGLVAQHPPARRSGAELALDYLCRWAQKHKNWRFQKTRQTWLLLHMYDSDKVPDEHFSTLLAYLEGLQGRARELTVQKAEALMRELDEEGSDPPLPGRAQRIRQVLQLLS", "length": 194 }, "evidence": [ { "id": "E7FH60", "url": "https://omabrowser.org/oma/group/E7FH60/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CXL3-1", "protein_name": "Cholesin", "gene_name": "Chlsn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAKHKRKGLEGTGKESKRQKITPAEETPRTSEAGPDKETASTLVQEASPELSPEERRVLERKLKKERKKEEKKRLREAGIAATQTAKVQTLPAKPSAATLALEYLQGWAQKQESWRFQKTRQTWLLLHMYDEDKVPDEHFPTLLDYLEGLRGSARELTVRKAEALMQKLDEAEPEDSGGSPGKVQRLRQVLQLLS", "length": 195 }, "evidence": [ { "id": "E7FH60", "url": "https://omabrowser.org/oma/group/E7FH60/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W019-1", "protein_name": "WKF domain-containing protein", "gene_name": "Dmel\\CG15877", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MARTELEKKVKRQGKKRKHEVTKNPEHAASDDEVANKSLILAPQVDQQEVPTDKPAKRRHKESEVSATKKQSRKNQAEEQVATSGSDESLPQKPQKRKQVQDANETKKLKRSKTQENNSDEDDDVDSQPTAAQLKEAARPENAYAVVTVRQKKKQKHQQRLEAQKSQSSNKDAKVNKEYLLKWKESRQDWKFNKLRQISIQQTAFDVEKLDDELWPTALEYLASSQGAARSKISQLAEEVIQKLDKEGEKLEDEAERRKLIESTQYRRARDLLQSFD", "length": 277 }, "evidence": [ { "id": "E7FH60", "url": "https://omabrowser.org/oma/group/E7FH60/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FH60", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FH60" }, { "id": "PF10180", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10180" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "WKF", "eco_id": "ECO_0000259", "start_pos": 167, "end_pos": 228, "start_aa": "Glu", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 44, "end_pos": 46 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7FDW7-1", "uniprot_ac": "E7FDW7", "uniprot_id": "E7FDW7_DANRE", "mass": { "chemical_mass": 114487.0, "monoisotopic_mass": 114487.0 }, "refseq": { "ac": "XP_021322089", "name": "NLR family member X1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322089" }, "gene_names": [ { "name": "nlrx1", "type": "recommended", "evidence": [ { "id": "E7FDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FDW7" } ] }, { "name": "nlrx1", "type": "synonym", "evidence": [ { "id": "XP_021322089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322089" } ] } ], "protein_names": [ { "name": "NLR family member X1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021322089", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322089" }, { "id": "E7FDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FDW7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133190) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021322089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322089" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FDW7", "url": "https://www.uniprot.org/uniprotkb/E7FDW7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nlrx1", "url": "https://www.uniprot.org/uniprotkb/E7FDW7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-071119-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071119-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000073724", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000073724", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "557335", "url": "https://www.ncbi.nlm.nih.gov/gene/557335", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007111", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007111", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR048900", "url": "https://www.ebi.ac.uk/interpro/entry/IPR048900", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051261", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051261", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:557335", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557335", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CVEPGHR", "url": "https://omabrowser.org/oma/group/CVEPGHR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7FDW7", "url": "https://www.orthodb.org/?gene=E7FDW7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24106", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24106", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05729", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05729", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF21402", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF21402", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-936440", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-936440", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9758274", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9758274", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_021322089", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021322089", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PLL8", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLL8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PLL8-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PLL8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCU9", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCU9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HCU9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HCU9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FDW7", "url": "https://www.uniprot.org/uniprotkb/E7FDW7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FDW7-1", "url": "https://www.uniprot.org/uniprotkb/E7FDW7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-071119-3", "url": "https://zfin.org/ZDB-GENE-071119-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MWRFGRPSGSEVLKWRCQRSSRDTCCKLHTMALQKTVNLSLQSAGICRNIKRCHLSFPIKTASSCRNAWKKQLTPMCYSASGFNHRLFCTSQPVTDPIEIHRQKLALWFSHIPQEERQFSGYVSPETMHVEPLILERHPDEDRGLSPFKEKTSVCAQQSLTVGDLFHDSNHGKARGLNILMYGAVGTGKSTVIRKLVQDWCDGSLFSQFKLMLPFSCEDISQLSKAISLRDLVGRKYMHLRKTPYLSGENDMARDVLFIFHGMEKMKLDFRISSTELCSDPNEALLSGAIVVNLLRKYMLPEASILVTTRLSAVDRVPKKYINRYVQICGFNDLDRQRAYFTSRLLQQHEGKPDRAAEMLIEMLYLNLQRESQLATACFLPSYCWLTCATLHLLHFTDTKSPIRTLTGIYTSFMRLNFGGEVITLNGGVSSQEQQNSLMLYVVRTVGKLAFDGITNKRTSFTAEELEQWVGGKTKTDEELRELAVFRTDVLDFFLVPRDDYGSDPETKGRRYVFAVPIMQEYLAALYVVLGENKTVLEKLTKEVSEALGPASEDITSLLSVLSKIIPFRIFAIFNLLKLFPKLFEKVSSYSKGRIANTMAAEMFRSEDSFNEDVLDQVEQSLLGVHGPQPQEEIYTRAFELYPIFMGGLLHYGNRRLLDQLGCNIKSHTVSQITRALRKNLIKQSQKNQPPEELMDLLVLLYEFQNPRLTAEVLQSIKSLNLSTVRMTPHKCFVLSTVLGCTTSSFHLNELNLSSCHITPELLQMLWPAFRHTRNLNLQFNSLDPESCILLRDLLLEPNCTIKSLQLCDNYLSDSGISHLLEALSGNHSLQRLNLMHTGLSDKSALLLAEKLGQHDQLKELNVAYNNIGDSAALTLVDACREHPSIHTVHLYLNQLTDVAKQSLYVRGGPRVKEGRRVKVLASVTEGSDISEDWHPILSVIGKNSLSWERDRVREQLLVFLKDLEWGRKQHLSFWKKMHFRRVESVVRQMLRFIEKSSDTGTGTK", "length": 1005, "header": "tr|E7FDW7-1|E7FDW7_DANRE Isoform 1 of NLR family member X1 isoform X1 OS=Danio rerio OX=7955 GN=nlrx1 PE=1 SV=1 CANONICAL=E7FDW7-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PLL8-1", "url": "https://www.uniprot.org/uniprotkb/E7FDW7/entry#A0A8M9PLL8-1", "sequence": { "sequence": "MWRFGRPSGSEVLKWRCQRSSRDTCCKLHTMALQKTVNLSLQSAGICRNIKRCHLSFPIKTASSCRNAWKKQLTPMCYSASGFNHRLFCTSQPVTDPIEIHRQKLALWFSHIPQEERQFSGYVSPETMHVEPLILERHPDEDRGLSPFKEKTSVCAQQSLTVGDLFHDSNHGKARGLNILMYGAVGTGKSTVIRKLVQDWCDGSLFSQFKLMLPFSCEDISQLSKAISLRDLVGRKYMHLRKTPYLSGENDMARDVLFIFHGMEKMKLDFRISSTELCSDPNEALLSGAIVVNLLRKYMLPEASILVTTRLSAVDRVPKKYINRYVQICGFNDLDRQRAYFTSRLLQQHEGKPDRAAEMLIEMLYLNLQRESQLATACFLPSYCWLTCATLHLLHFTDTKSPIRTLTGIYTSFMRLNFGGEVITLNGGVSSQEQQNSLMLYVVRTVGKLAFDGITNKRTSFTAEELEQWVGGKTKTDEELRELAVFRTDVLDFFLVPRDDYGSDPETKGRRYVFAVPIMQEYLAALYVVLGENKTVLEKLTKEVSEALGPASEDITSLLSVLSKIIPFRIFAIFNLLKLFPKLFEKVSSYSKGRIANTMAAEMFRSEDSFNEDVLDQVEQSLLGVHGPQPQEEIYTRAFELYPIFMGGLLHYGNRRLLDQLGCNIKSHTVSQITRALRKNLIKQSQKNQPPEELMDLLVLLYEFQNPRLTAEVLQSIKSLNLSTVRMTPHKCFVLSTVLGCTTSSFHLNELNLSSCHITPELLQMLWPAFRHTRNLKLCDNYLSDSGISHLLEALSGNHSLQRLNLMHTGLSDKSALLLAEKLGQHDQLKELNVAYNNIGDSAALTLVDACREHPSIHTVHLYLNQLTDVAKQSLYVRGGPRVKEGRRVKVLASVTEGSDISEDWHPILSVIGKNSLSWERDRVREQLLVFLKDLEWGRKQHLSFWKKMHFRRVESVVRQMLRFIEKSSDTGTGTK", "length": 976, "header": "tr|A0A8M9PLL8-1|E7FDW7_DANRE Computationally mapped isoform of NLR family member X1 isoform X1 OS=Danio rerio OX=7955 GN=nlrx1 PE=1 SV=1 CANONICAL=E7FDW7-1" }, "locus": {} }, { "isoform_ac": "A0AC58HCU9-1", "url": "https://www.uniprot.org/uniprotkb/E7FDW7/entry#A0AC58HCU9-1", "sequence": { "sequence": "MLIEMLYLNLQRESQLATACFLPSYCWLTCATLHLLHFTDTKSPIRTLTGIYTSFMRLNFGGEVITLNGGVSSQEQQNSLMLYVVRTVGKLAFDGITNKRTSFTAEELEQWVGGKTKTDEELRELAVFRTDVLDFFLVPRDDYGSDPETKGRRYVFAVPIMQEYLAALYVVLGENKTVLEKLTKEVSEALGPASEDITSLLSVLSKIIPFRIFAIFNLLKLFPKLFEKVSSYSKGRIANTMAAEMFRSEDSFNEDVLDQVEQSLLGVHGPQPQEEIYTRAFELYPIFMGGLLHYGNRRLLDQLGCNIKSHTVSQITRALRKNLIKQSQKNQPPEELMDLLVLLYEFQNPRLTAEVLQSIKSLNLSTVRMTPHKCFVLSTVLGCTTSSFHLNELNLSSCHITPELLQMLWPAFRHTRNLNLQFNSLDPESCILLRDLLLEPNCTIKSLQLCDNYLSDSGISHLLEALSGNHSLQRLNLMHTGLSDKSALLLAEKLGQHDQLKELNVAYNNIGDSAALTLVDACREHPSIHTVHLYLNQLTDVAKQSLYVRGGPRVKEGRRVKVLASVTEGSDISEDWHPILSVIGKNSLSWERDRVREQLLVFLKDLEWGRKQHLSFWKKMHFRRVESVVRQMLRFIEKSSDTGTGTK", "length": 647, "header": "tr|A0AC58HCU9-1|A0AC58HCU9_DANRE Computationally mapped isoform of NLR family member X1 isoform X3 OS=Danio rerio OX=7955 GN=nlrx1 PE=1 SV=1 CANONICAL=E7FDW7-1" }, "locus": {} }, { "isoform_ac": "E7FDW7-1", "url": "https://www.uniprot.org/uniprotkb/E7FDW7/entry#E7FDW7-1", "sequence": { "sequence": "MWRFGRPSGSEVLKWRCQRSSRDTCCKLHTMALQKTVNLSLQSAGICRNIKRCHLSFPIKTASSCRNAWKKQLTPMCYSASGFNHRLFCTSQPVTDPIEIHRQKLALWFSHIPQEERQFSGYVSPETMHVEPLILERHPDEDRGLSPFKEKTSVCAQQSLTVGDLFHDSNHGKARGLNILMYGAVGTGKSTVIRKLVQDWCDGSLFSQFKLMLPFSCEDISQLSKAISLRDLVGRKYMHLRKTPYLSGENDMARDVLFIFHGMEKMKLDFRISSTELCSDPNEALLSGAIVVNLLRKYMLPEASILVTTRLSAVDRVPKKYINRYVQICGFNDLDRQRAYFTSRLLQQHEGKPDRAAEMLIEMLYLNLQRESQLATACFLPSYCWLTCATLHLLHFTDTKSPIRTLTGIYTSFMRLNFGGEVITLNGGVSSQEQQNSLMLYVVRTVGKLAFDGITNKRTSFTAEELEQWVGGKTKTDEELRELAVFRTDVLDFFLVPRDDYGSDPETKGRRYVFAVPIMQEYLAALYVVLGENKTVLEKLTKEVSEALGPASEDITSLLSVLSKIIPFRIFAIFNLLKLFPKLFEKVSSYSKGRIANTMAAEMFRSEDSFNEDVLDQVEQSLLGVHGPQPQEEIYTRAFELYPIFMGGLLHYGNRRLLDQLGCNIKSHTVSQITRALRKNLIKQSQKNQPPEELMDLLVLLYEFQNPRLTAEVLQSIKSLNLSTVRMTPHKCFVLSTVLGCTTSSFHLNELNLSSCHITPELLQMLWPAFRHTRNLNLQFNSLDPESCILLRDLLLEPNCTIKSLQLCDNYLSDSGISHLLEALSGNHSLQRLNLMHTGLSDKSALLLAEKLGQHDQLKELNVAYNNIGDSAALTLVDACREHPSIHTVHLYLNQLTDVAKQSLYVRGGPRVKEGRRVKVLASVTEGSDISEDWHPILSVIGKNSLSWERDRVREQLLVFLKDLEWGRKQHLSFWKKMHFRRVESVVRQMLRFIEKSSDTGTGTK", "length": 1005, "header": "tr|E7FDW7-1|E7FDW7_DANRE Isoform 1 of NLR family member X1 isoform X1 OS=Danio rerio OX=7955 GN=nlrx1 PE=1 SV=1 CANONICAL=E7FDW7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:557335", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:557335", "resource": "KEGG Pathway" }, { "id": "R-DRE-936440", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-936440", "resource": "Reactome", "description": "Negative regulators of DDX58/IFIH1 signaling" }, { "id": "R-DRE-9758274", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9758274", "resource": "Reactome", "description": "Regulation of NF-kappa B signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3TL44-1", "protein_name": "NLR family member X1", "gene_name": "Nlrx1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRWGCHLPRTSWGSGLGRTPQLPDEHISFLIQWSWPFKGVHPLRPPRAFIRYHGNSADSAPPPGRHGQLFRSISATEAIQRHRRNLTEWFSRLPREERQFGPTFALDTVHVDPVIRESTPDELLRPSTELATGHQQTQAGLPPLALSQLFDPDSCGRRVQTVVLYGTVGTGKSTLVRKMVLDWCYGRLPAFELLIPFSCEDLSSLGSTPASLCQLVTQRYTPLKEVLPLMTAAGSRLLFVLHGLERLNLDFRLAGTGLCSDPEEPGPPAAIIVNLLRKYMLPEASILVTTRPSTISRIPSKYVGRYGEICGFSDTNLQKLYFQLRLNQPDCGYGAGGASVSVTPAQRDNLIQMLSRNLEGHHQIAAACFLPSYCWLVCATLHFLHAPTPAGQTLTSIYTSFLRLNFSGETLDSTHTSNLSLMSYAARTMGKLAYEGVSSRKTYFSEEDVRGCLEAGIKTEEEFQLLQIFRRDALRFFLAPCVEPGHLGTFVFTVPAMQEYLAALYIVLGLRKTALQRVGKEVVEFVGRVGEDVSLVLGIVAKLLPLRILPLLFNLLKVVPRVFGRMVSKSREAVAQAMVLEMFREEDYYNDDVLDQMGASILGVEGPRRHPDEPSEDEVFELFPMFMGGLLSAHNRAVLAQLGCPIKNLDALENAQAIKKKLGKLGRQVLPPSELLDHLFFHYEFQNQRFSAEVLGSLRQLNLAGVRMTPLKCTVVASVLGSGRHPLDEVNLASCQLDPAGLHTLMPVLLRARKLGLQLNNLGPEACRDLRDLLLHDQCQITTLRLSNNPLTAAGVGLLMDGLAGNTSVTHLSLLHTDLGDEGLELLAAQLDRNKQLQELNVAYNGAGDTVALALAKAAREHPSLELLHLYFNELSSEGRQVLRDLGGSGEGGARVVASLTEGTAVSEYWSVILSEVQRNVHSWDPLRVQRHLKLLLRDLEDSRGATLNPWRKAQLLRVEGEVKTLLEQLGGSGH", "length": 975 }, "evidence": [ { "id": "HGNC:29890", "url": "https://alliancegenome.org/gene/HGNC:29890#orthology", "database": "AGR" }, { "id": "MGI:2429611", "url": "https://alliancegenome.org/gene/MGI:2429611#orthology", "database": "AGR" }, { "id": "RGD:1311293", "url": "https://alliancegenome.org/gene/RGD:1311293#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071119-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071119-3#orthology", "database": "AGR" }, { "id": "E7FDW7", "url": "https://omabrowser.org/oma/group/E7FDW7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q5FVQ8-1", "protein_name": "NLR family member X1", "gene_name": "Nlrx1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRWGCHLPRTSWGSGLGRTVPLPDELRIQSSWPFKGVHHPLRPPRAFIRHHGNSADSAPPPGRHGQLFRSISATEAIQRHRRNLTEWFSRLPREERQFGPTFALDTVHVDPVIRESTPDDLLRPSTELATGHQRTQAELPPLALSQLFDPDACGRRVQTVVLYGTVGTGKSTLVRKMVLDWCYGRLPAFELLIPFSCEDLSSLGSTPASLCQLVTQRYTPLKEVLPLMNAAGSRLLFVLHGLERLNLDFRLAGTGLCSDPEEPGAPAAIMVNLLRKYMLPEASILVTTRPSAIGRIPSKYVGRYGEICGFSDTNLQKLYFQLRLNQPDCGYGAGGTGVSVTPAQRDNLIQMLSRNLEGHHQIAAACFLPSYCWLVCATLHFLHAPTSAGQTLTSIYTSFLRLNFNGETLDSTDPSNLSLMSYAARTMGKLAYEGVSSRKTYFSEEDVRGCLEAGIKTEEEFQLLQIFRRDALRFFLAPCVEPGHLGTFVFTVPAMQEYLAALYIVLGLRKTALQRVGKEVFEFVGRVGEDVSLVLGIVAKLLPLRILPLLFNLLKVVPRVFGRMVSKSREAVAQAMVLEMFREEDYYNDDVLDQMGASILGVEGPRRHPDEPPEDEVFELFPMFMSGLLSAHNRAVLAQLGCPIKNLDALENAQAIKKKLGKMGRQVLPPSELLDHLFFHYEFQNQRFSAEVLGSLRQLNLAGVRMTPLKCTVVASVLGSGRHPLDEVNLASCQLDPAGLHTLMPVLLRARKLGLQLNNLGPEACRDLRDLLLHDQCQITTLRLSNNPLTAAGVGVLMDGLAGNTSVTHLSLLHTDLGDEGLELLAAQLDRNKQLQELNVAYNGAGDTVALALAKAARKHPSLELLHLYFNELSSEGRQVLRDLGGSGEGGARVVASLTEGTAVSEYWSVILSEVQRNLNSWDPVRVQRHLKLLLRDLEDSRGATLNPWRKAQLLRVESEVKTLLEQLGGSGH", "length": 973 }, "evidence": [ { "id": "HGNC:29890", "url": "https://alliancegenome.org/gene/HGNC:29890#orthology", "database": "AGR" }, { "id": "MGI:2429611", "url": "https://alliancegenome.org/gene/MGI:2429611#orthology", "database": "AGR" }, { "id": "RGD:1311293", "url": "https://alliancegenome.org/gene/RGD:1311293#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071119-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071119-3#orthology", "database": "AGR" }, { "id": "E7FDW7", "url": "https://omabrowser.org/oma/group/E7FDW7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q86UT6-1", "protein_name": "NLR family member X1", "gene_name": "NLRX1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRWGHHLPRASWGSGFRRALQRPDDRIPFLIHWSWPLQGERPFGPPRAFIRHHGSSVDSAPPPGRHGRLFPSASATEAIQRHRRNLAEWFSRLPREERQFGPTFALDTVHVDPVIRESTPDELLRPPAELALEHQPPQAGLPPLALSQLFNPDACGRRVQTVVLYGTVGTGKSTLVRKMVLDWCYGRLPAFELLIPFSCEDLSSLGPAPASLCQLVAQRYTPLKEVLPLMAAAGSHLLFVLHGLEHLNLDFRLAGTGLCSDPEEPQEPAAIIVNLLRKYMLPQASILVTTRPSAIGRIPSKYVGRYGEICGFSDTNLQKLYFQLRLNQPYCGYAVGGSGVSATPAQRDHLVQMLSRNLEGHHQIAAACFLPSYCWLVCATLHFLHAPTPAGQTLTSIYTSFLRLNFSGETLDSTDPSNLSLMAYAARTMGKLAYEGVSSRKTYFSEEDVCGCLEAGIRTEEEFQLLHIFRRDALRFFLAPCVEPGRAGTFVFTVPAMQEYLAALYIVLGLRKTTLQKVGKEVAELVGRVGEDVSLVLGIMAKLLPLRALPLLFNLIKVVPRVFGRMVGKSREAVAQAMVLEMFREEDYYNDDVLDQMGASILGVEGPRRHPDEPPEDEVFELFPMFMGGLLSAHNRAVLAQLGCPIKNLDALENAQAIKKKLGKLGRQVLPPSELLDHLFFHYEFQNQRFSAEVLSSLRQLNLAGVRMTPVKCTVVAAVLGSGRHALDEVNLASCQLDPAGLRTLLPVFLRARKLGLQLNSLGPEACKDLRDLLLHDQCQITTLRLSNNPLTAAGVAVLMEGLAGNTSVTHLSLLHTGLGDEGLELLAAQLDRNRQLQELNVAYNGAGDTAALALARAAREHPSLELLHLYFNELSSEGRQVLRDLGGAAEGGARVVVSLTEGTAVSEYWSVILSEVQRNLNSWDRARVQRHLELLLRDLEDSRGATLNPWRKAQLLRVEGEVRALLEQLGSSGS", "length": 975 }, "evidence": [ { "id": "HGNC:29890", "url": "https://alliancegenome.org/gene/HGNC:29890#orthology", "database": "AGR" }, { "id": "MGI:2429611", "url": "https://alliancegenome.org/gene/MGI:2429611#orthology", "database": "AGR" }, { "id": "RGD:1311293", "url": "https://alliancegenome.org/gene/RGD:1311293#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-071119-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071119-3#orthology", "database": "AGR" }, { "id": "E7FDW7", "url": "https://omabrowser.org/oma/group/E7FDW7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ATP binding", "id": "GO:0005524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005524", "evidence": [ { "database": "UniProtKB", "id": "E7FDW7", "url": "https://www.uniprot.org/uniprotkb/E7FDW7" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrion", "id": "GO:0005739", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005739", "evidence": [ { "database": "UniProtKB", "id": "E7FDW7", "url": "https://www.uniprot.org/uniprotkb/E7FDW7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "negative regulation of canonical NF-kappaB signal transduction", "id": "GO:0043124", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043124", "evidence": [ { "database": "UniProtKB", "id": "E7FDW7", "url": "https://www.uniprot.org/uniprotkb/E7FDW7" } ], "pmid": "" }, { "name": "negative regulation of RIG-I signaling pathway", "id": "GO:0039536", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0039536", "evidence": [ { "database": "UniProtKB", "id": "E7FDW7", "url": "https://www.uniprot.org/uniprotkb/E7FDW7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 38, "end_pos": 40, "annotation": "n_glycosylation_sequon" }, { "start_pos": 533, "end_pos": 535, "annotation": "n_glycosylation_sequon" }, { "start_pos": 721, "end_pos": 723, "annotation": "n_glycosylation_sequon" }, { "start_pos": 752, "end_pos": 754, "annotation": "n_glycosylation_sequon" }, { "start_pos": 799, "end_pos": 801, "annotation": "n_glycosylation_sequon" }, { "start_pos": 827, "end_pos": 829, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FDW7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FDW7" }, { "id": "PS50837", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "NACHT", "eco_id": "ECO_0000259", "start_pos": 177, "end_pos": 310, "start_aa": "Leu", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 38, "end_pos": 40 }, { "start_pos": 533, "end_pos": 535 }, { "start_pos": 721, "end_pos": 723 }, { "start_pos": 752, "end_pos": 754 }, { "start_pos": 799, "end_pos": 801 }, { "start_pos": 827, "end_pos": 829 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7FD93-1", "uniprot_ac": "E7FD93", "uniprot_id": "E7FD93_DANRE", "mass": { "chemical_mass": 73954.0, "monoisotopic_mass": 73954.0 }, "refseq": { "ac": "XP_005161311", "name": "DNA damage-induced apoptosis suppressor protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161311" }, "gene_names": [ { "name": "ddias", "type": "recommended", "evidence": [ { "id": "E7FD93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FD93" } ] }, { "name": "ddias", "type": "synonym", "evidence": [ { "id": "XP_005161311", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161311" } ] } ], "protein_names": [ { "name": "DNA damage-induced apoptosis suppressor protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005161311", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161311" }, { "id": "E7FD93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FD93/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005161311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161311" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FD93", "url": "https://www.uniprot.org/uniprotkb/E7FD93" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ddias", "url": "https://www.uniprot.org/uniprotkb/E7FD93", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050208-281", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-281", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000088690", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000088690", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "497565", "url": "https://www.ncbi.nlm.nih.gov/gene/497565", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013955", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013955", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043522", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043522", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:497565", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:497565", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFESSAH", "url": "https://omabrowser.org/oma/group/MFESSAH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7FD93", "url": "https://www.orthodb.org/?gene=E7FD93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35537", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35537", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35537:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35537:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08646", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08646", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005161311", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161311", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8M9PUM0", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PUM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8M9PUM0-1", "url": "https://www.uniprot.org/uniprotkb/A0A8M9PUM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FD93", "url": "https://www.uniprot.org/uniprotkb/E7FD93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FD93-1", "url": "https://www.uniprot.org/uniprotkb/E7FD93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050208-281", "url": "https://zfin.org/ZDB-GENE-050208-281", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSTRALVSCSILSLQDSCFVYPCCKDCLSRVSLENKRVTCGRCGFTCDSQNVDYRYRLSFKVSRNQDIFGVTVFGGCLNPFFGITAGGLQRYIELQKSDGKHTVQELLVKALEDCFIGRSVIFGLKVPCKKAKTSSLSGQFVACQIVAPCESLMGCTVIDYLKTLQQANSNSCHYESASNVCFSQQKNSQTSQSFDYTPPSCAQLNSLPSSQEFTISKVWQSPGLRFLPAELNNEFLQQSRVCDNIASPNIETRTSKCRTSETNQPKHEKLKDETQNNHRNSFSSSCDMFDSSAHFNMSTACDAVNPLSTFSSQRDYEVTTSTQHLVRTVPVENLDARVDEKALYSHSGQDLSLNLEDAPLSESLQDFVEPPISEIIETRECSAGEKDKGIQEQNGCCQIDSSVSIQMPICGEHLTPPMCSVNIIERKESCENDCLENPETTLNPYEIPRFLTTTSSRLKGEPFSSANNRLSFSNKKELCLNRKIPNSPSVAFCSVNHEKGKYFRHCTQSELHSVNCKVKQELIVFDDHEDKYNCSVDLFASGQSGMDMNLSDVTEISKVNEQRSVNTLEPGVSGPLLFSPCLQSTPVSHFQHSCGPKTGRSRKRVGSLCSIKCEFKTKTTDLCLSDKRLKFDQMPNDECIENTKCNLSATEWSRDLFENSF", "length": 663, "header": "tr|E7FD93-1|E7FD93_DANRE Isoform 1 of DNA damage-induced apoptosis suppressor protein isoform X1 OS=Danio rerio OX=7955 GN=ddias PE=4 SV=1 CANONICAL=E7FD93-1" }, "isoforms": [ { "isoform_ac": "A0A8M9PUM0-1", "url": "https://www.uniprot.org/uniprotkb/E7FD93/entry#A0A8M9PUM0-1", "sequence": { "sequence": "MSSTRALVSCSILSLQDSCFVYPCCKDCLSRVSLENKRYIELQKSDGKHTVQELLVKALEDCFIGRSVIFGLKVPCKKAKTSSLSGQFVACQIVAPCESLMGCTVIDYLKTLQQANSNSCHYESASNVCFSQQKNSQTSQSFDYTPPSCAQLNSLPSSQEFTISKVWQSPGLRFLPAELNNEFLQQSRVCDNIASPNIETRTSKCRTSETNQPKHEKLKDETQNNHRNSFSSSCDMFDSSAHFNMSTACDAVNPLSTFSSQRDYEVTTSTQHLVRTVPVENLDARVDEKALYSHSGQDLSLNLEDAPLSESLQDFVEPPISEIIETRECSAGEKDKGIQEQNGCCQIDSSVSIQMPICGEHLTPPMCSVNIIERKESCENDCLENPETTLNPYEIPRFLTTTSSRLKGEPFSSANNRLSFSNKKELCLNRKIPNSPSVAFCSVNHEKGKYFRHCTQSELHSVNCKVKQELIVFDDHEDKYNCSVDLFASGQSGMDMNLSDVTEISKVNEQRSVNTLEPGVSGPLLFSPCLQSTPVSHFQHSCGPKTGRSRKRVGSLCSIKCEFKTKTTDLCLSDKRLKFDQMPNDECIENTKCNLSATEWSRDLFENSF", "length": 609, "header": "tr|A0A8M9PUM0-1|E7FD93_DANRE Computationally mapped isoform of DNA damage-induced apoptosis suppressor protein isoform X1 OS=Danio rerio OX=7955 GN=ddias PE=4 SV=1 CANONICAL=E7FD93-1" }, "locus": {} }, { "isoform_ac": "E7FD93-1", "url": "https://www.uniprot.org/uniprotkb/E7FD93/entry#E7FD93-1", "sequence": { "sequence": "MSSTRALVSCSILSLQDSCFVYPCCKDCLSRVSLENKRVTCGRCGFTCDSQNVDYRYRLSFKVSRNQDIFGVTVFGGCLNPFFGITAGGLQRYIELQKSDGKHTVQELLVKALEDCFIGRSVIFGLKVPCKKAKTSSLSGQFVACQIVAPCESLMGCTVIDYLKTLQQANSNSCHYESASNVCFSQQKNSQTSQSFDYTPPSCAQLNSLPSSQEFTISKVWQSPGLRFLPAELNNEFLQQSRVCDNIASPNIETRTSKCRTSETNQPKHEKLKDETQNNHRNSFSSSCDMFDSSAHFNMSTACDAVNPLSTFSSQRDYEVTTSTQHLVRTVPVENLDARVDEKALYSHSGQDLSLNLEDAPLSESLQDFVEPPISEIIETRECSAGEKDKGIQEQNGCCQIDSSVSIQMPICGEHLTPPMCSVNIIERKESCENDCLENPETTLNPYEIPRFLTTTSSRLKGEPFSSANNRLSFSNKKELCLNRKIPNSPSVAFCSVNHEKGKYFRHCTQSELHSVNCKVKQELIVFDDHEDKYNCSVDLFASGQSGMDMNLSDVTEISKVNEQRSVNTLEPGVSGPLLFSPCLQSTPVSHFQHSCGPKTGRSRKRVGSLCSIKCEFKTKTTDLCLSDKRLKFDQMPNDECIENTKCNLSATEWSRDLFENSF", "length": 663, "header": "tr|E7FD93-1|E7FD93_DANRE Isoform 1 of DNA damage-induced apoptosis suppressor protein isoform X1 OS=Danio rerio OX=7955 GN=ddias PE=4 SV=1 CANONICAL=E7FD93-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:497565", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:497565", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q6NZG4-1", "protein_name": "DNA damage-induced apoptosis suppressor protein", "gene_name": "Ddias", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MNKRRKFLFASVLAVQNSNFIYPSCQRCFSKIILESKRFTCPKCGSSGDTGSTNYRYKLSLKVAESSKLFFITVFGSCLDTFFGLTATGLHRYLGDSIKNLETLDSGRTQSLLTTAVEKCFVGQSFVFGVTNFGDVCGHDSDSSNFQQPCCKHRGEVRTLVASQIILPSPHVKGFTVIAYLHPLLHKKPHCGSQEHSSQSLTSDDSDSDLNNIQGSGNTSWFSESSVGEDFFRYWEPSLELTSSDSQVTSSDDFPASKQIMASGTPNQNRHCISVSEVTSSKNCHDSLQSLWSLHSCMDKNNTTGKLGEELGLPSPVCNSCHESRLSDSHFFPSQMQEPFEEHNLECYSKAEKNDYSQYDIACYQHHEVNTTPILQQRSSAFSLSSLKPEETANPSQNSDSLIWDDLPLSESLNKFLAVVESEVAVTEIDAKNRKQGMDKSIDKCHKNYSRLSLTPWRNTRALNTSCFSLRSSQAMMKDSGKEALFSNCKSNSSPHIQKESKADKTEAAVSIAGSRSDISEDFLPDTCSSALFTSSKDREAFITQKRTSGVLQQRNEISCRPSTSISDCSDLRSRYFTGCGQKLHSGTKGKLAIQNCSKKYSDASDLHKLENKHRWPKKEDDNFTICRKLTYPLETLCSSPESINTSKEMPYRPSNNNLTPSSSGDHEGSYNASADLFDYIAKDKDIGTEITKIPQDNLLPLEVPCTENYPINENRGQPSQKPSLQSISPSRYSRPRSQSDSECDFEESQDFVPCSQSTPVAGFHQRIHGLNGASKILPSIYSNPNANYKNRKNSPLTGQYQATSACSKNVKAFRQKPESPFVSSLTQANVFNHCPAAESLGNDVDEWVPPTTKKVFISDILGFRVMGLRKCLDLHYSPDPKELPRKKLIKVTHKTNI", "length": 898 }, "evidence": [ { "id": "MGI:1921291", "url": "https://alliancegenome.org/gene/MGI:1921291#orthology", "database": "AGR" }, { "id": "HGNC:26351", "url": "https://alliancegenome.org/gene/HGNC:26351#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-281", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-281#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IXT1-1", "protein_name": "DNA damage-induced apoptosis suppressor protein", "gene_name": "DDIAS", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNRRRKFLLASVLALQNSSFIYPSCQKCFSRIILVSKRSNCPKCGSTGESGNANYRYKLSLKVAESNKLFVITVFGSCLDTFFGLTATGLHRYIQDPNKIPETLDNDTTQNLLTKAVETCFVGQSFIFGVTNFENQPGQGSDASNFLQQCSDHKRKAKALVACQIVLPDPGIAGFTVIDYFHQLLQTFNFRKLQCDSQAPNNHLLALDHSNSDLSSIYTSDSTSDFFKSCSKDTFSKFWQPSLEFTCIVSQLTDNDDFSASEQSKAFGTLQQNRKSISIAEATGSSSCHDPIQDSWSLVSYMDKKSTAEKLGKELGLQAKELSAVHSSHHEIGVNDSNLFSLEMREPLESSNTKSFHSAVEIKNRSQHELPCFQHHGIDTPTSLQKRSACCPPSLLRLEETASSSQDGDPQIWDDLPFSESLNKFLAVLESEIAVTQADVSSRKHHVDNDIDKFHADHSRLSVTPQRTTGALHTPPIALRSSQVIVKANCSKDDFLFNCKGNLSPSVEKESQPDNKVEAVSVNHNGRDMSEYFLPNPYLSALSSSSKDLETIVTLKKTIRISPHRESDHSSLNNKYLNGCGEISVSEMNEKLTTLCYRKYNDVSDLCKLENKQYCRWSKNQDDSFTICRKLTYPLETLCNSPNRSTNTLKEMPWGHINNNVTQSYSIGYEGSYDASADLFDDIAKEMDIATEITKKSQDILLKWGTSLAESHPSESDFSLRSLSEDFIQPSQKLSLQSLSDSRHSRTCSPTPHFQSDSEYNFENSQDFVPCSQSTPISGFHQTRIHGINRAFKKPVFYSDLDGNYEKIRIFPENDKQQASPSCPKNIKTPSQKIRSPIVSGVSQPDVFNHYPFAECHETDSDEWVPPTTQKIFPSDMLGFQGIGLGKCLAAYHFPDQQELPRKKLKHIRQGTNKGLIKKKLKNMLAAVVTKKKTHKYNCKSSGWISKCPDIQVLAAPQLHPILGPDSCSEVKCCLPFSEKGPPSVCETRSAWSPELFS", "length": 998 }, "evidence": [ { "id": "MGI:1921291", "url": "https://alliancegenome.org/gene/MGI:1921291#orthology", "database": "AGR" }, { "id": "HGNC:26351", "url": "https://alliancegenome.org/gene/HGNC:26351#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050208-281", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050208-281#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage", "id": "GO:1902230", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902230", "evidence": [ { "database": "UniProtKB", "id": "E7FD93", "url": "https://www.uniprot.org/uniprotkb/E7FD93" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 298, "end_pos": 300, "annotation": "n_glycosylation_sequon" }, { "start_pos": 535, "end_pos": 537, "annotation": "n_glycosylation_sequon" }, { "start_pos": 551, "end_pos": 553, "annotation": "n_glycosylation_sequon" }, { "start_pos": 648, "end_pos": 650, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FD93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FD93" }, { "id": "PF08646", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08646" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Replication factor A C-terminal", "eco_id": "ECO_0000259", "start_pos": 8, "end_pos": 110, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 298, "end_pos": 300 }, { "start_pos": 535, "end_pos": 537 }, { "start_pos": 551, "end_pos": 553 }, { "start_pos": 648, "end_pos": 650 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EZY0-1", "uniprot_ac": "E7EZY0", "uniprot_id": "E7EZY0_DANRE", "mass": { "chemical_mass": 28325.0, "monoisotopic_mass": 28325.0 }, "refseq": { "ac": "NP_001373427", "name": "peptidase inhibitor R3HDML precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373427" }, "gene_names": [ { "name": "r3hdml", "type": "recommended", "evidence": [ { "id": "E7EZY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZY0" } ] }, { "name": "r3hdml", "type": "synonym", "evidence": [ { "id": "NP_001373427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373427" } ] }, { "name": "si:dkey-24l7.3", "type": "synonym", "evidence": [ { "id": "NP_001373427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373427" }, { "id": "E7EZY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZY0" } ] } ], "protein_names": [ { "name": "Peptidase inhibitor R3HDML precursor", "type": "synonym", "evidence": [ { "id": "E7EZY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZY0/entry#names_and_taxonomy" } ] }, { "name": "peptidase inhibitor R3HDML precursor", "type": "synonym", "evidence": [ { "id": "NP_001373427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373427" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH592941.1, SRR32588721.2624917.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505389, SAMEA4476731 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000023.1. On or before Aug 24, 2020 this sequence version replaced XP_021329373.1, XP_690466.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001373427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373427" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZY0", "url": "https://www.uniprot.org/uniprotkb/E7EZY0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "r3hdml", "url": "https://www.uniprot.org/uniprotkb/E7EZY0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-275", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-275", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd18815", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd18815", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "561976", "url": "https://www.ncbi.nlm.nih.gov/gene/561976", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001283", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001283", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR002413", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002413", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR014044", "url": "https://www.ebi.ac.uk/interpro/entry/IPR014044", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR047899", "url": "https://www.ebi.ac.uk/interpro/entry/IPR047899", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561976", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561976", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7EZY0", "url": "https://www.orthodb.org/?gene=E7EZY0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10334", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10334", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00188", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00188", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001373427", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373427", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EZY0", "url": "https://www.uniprot.org/uniprotkb/E7EZY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZY0-1", "url": "https://www.uniprot.org/uniprotkb/E7EZY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-275", "url": "https://zfin.org/ZDB-GENE-090313-275", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNLVCAQLVFAVTLWTAGAEAGIVAVCSGTSLLQAEQLSMEAEVRNSSDGSTFRVRRRRFISGKDMTALLDYHNRVRSQVFPPAANMEYMVWDERLAKSAEFWASQCIWEHGPHHFLQHIGQNLSIISGRYKSIIDLVKSWYDERHSFSYPSRCSGSVCTHYTQMVWAASNKIGCAIKKCSDIFVFGSMWKQATLLVCNYAIKGNWVGEAPYKIGRPCSACPSSYGGSCNKNQCDSRPKSRRNTNGFRGYKQ", "length": 252, "header": "tr|E7EZY0-1|E7EZY0_DANRE Isoform 1 of Peptidase inhibitor R3HDML precursor OS=Danio rerio OX=7955 GN=r3hdml PE=3 SV=1 CANONICAL=E7EZY0-1" }, "isoforms": [ { "isoform_ac": "E7EZY0-1", "url": "https://www.uniprot.org/uniprotkb/E7EZY0/entry#E7EZY0-1", "sequence": { "sequence": "MNLVCAQLVFAVTLWTAGAEAGIVAVCSGTSLLQAEQLSMEAEVRNSSDGSTFRVRRRRFISGKDMTALLDYHNRVRSQVFPPAANMEYMVWDERLAKSAEFWASQCIWEHGPHHFLQHIGQNLSIISGRYKSIIDLVKSWYDERHSFSYPSRCSGSVCTHYTQMVWAASNKIGCAIKKCSDIFVFGSMWKQATLLVCNYAIKGNWVGEAPYKIGRPCSACPSSYGGSCNKNQCDSRPKSRRNTNGFRGYKQ", "length": 252, "header": "tr|E7EZY0-1|E7EZY0_DANRE Isoform 1 of Peptidase inhibitor R3HDML precursor OS=Danio rerio OX=7955 GN=r3hdml PE=3 SV=1 CANONICAL=E7EZY0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of beta-Cell Mass Deficits.", "journal": "Mol. Endocrinol.", "date": "2016", "authors": "O'Hare Elizabeth A, Yerges-Armstrong Laura M, Perry James A, Shuldiner Alan R, Zaghloul Norann A", "evidence": [ { "database": "UniProtKB", "id": "E7EZY0", "url": "https://www.uniprot.org/uniprotkb/E7EZY0" } ], "reference": [ { "type": "PubMed", "id": "26963759", "url": "https://glygen.org/publication/PubMed/26963759" } ] } ], "pathway": [ { "id": "dre:561976", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561976", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1W2P7V2-1", "protein_name": "GLI pathogenesis-related 1 like 3", "gene_name": "Glipr1l3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALKKKLNFLWTLALYLIATRLPKAFGNDLPRVPSILDPKFIDAFLNIHNELRRKVQPPAADMNQVIWDQKLAKLAKAWTRECKLGHNPCTSKQYGCLLDYDFIGENIYLGEIETQPEDVVNNWYNENTDYNFVDNTCSKICRNYTQVFWAKTFKIGCAVSNCPNLTRYSAGLFVCNYSPTGNFLDFRPYRKGDPCSMCGQRKCENSLCRPMNRKTPHQKAACHVLVLGFILQRLL", "length": 236 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" }, { "id": "FB:FBgn0052679", "url": "https://alliancegenome.org/gene/FB:FBgn0052679#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A0A8M1RM30-1", "protein_name": "Cysteine-rich secretory protein LCCL domain-containing 2", "gene_name": "crispld2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MHALVSIALLFLGVSLAASLFLPDSLELRQLMQRYQEELEPNSTKPDAPVRTRRAIEWSDREEILKLHNKLRGEVYPTASNMEYMIWDDELERSATSWAEQCQWEHGPQDLLMSIGQNLAVHWGRYRSPAYHVQAWYDEVKDYTYPYPHECNPWCPERCSGPMCTHYTQLVWATTNRVGCAVHVCPRMNVWGEIWENAVYLVCNYSPKGNWIGEAPYQHGRPCSQCPPSYGGVCRDNLCYKRDSERQETPEMNEVEKPQEPLQPRTTPPKPQPKPSSPKKPANAKPSSPKTTRNTYLAQNIKCETKMRDKCKGATCNRYNCPANCLNKQGKVWGTLYYDVQSSICRAAIHYGVIDNNGGLVDVTRKDSFPFFVKATKNGVESFSKYKAGNAFMVSNVQEQTIDCYATVAEICPFKSTTSHCPRVFCPANCINEPSYWAPVVGSNIYADGSSICRAAIHAGVIKASGGYVDLLALDKRKTYTGTLKNGIQSESKTNREGGSFRVFAVRE", "length": 508 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2B5H0-1", "protein_name": "Glioma pathogenesis-related protein 1b isoform X1", "gene_name": "glipr1b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDSLGGLLLRISVVLYGSCSVLALLPGITEPEFIRRCVKAHNTHRARVSPPAAGARSMVRQVFGMQSWDKELAKGARDRARHCKGSHYPSLGHFGHPLFGWMGENIWLGSPFSAFSVENAVHRWSKEGAYSVKNNNCSRLCGHYAQLMWSTSFKMGCAVNVCSKGIENFSTHPESTIFVCNYGDTGQVHGVTPYMAMGCSGCGSEICRDNVCRYDWFPGWDYGPPSSAHSVSYWQTNLGLCLLGVCWLLHFYATH", "length": 255 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M6YY67-1", "protein_name": "GLIPR1-like protein 1 isoform X1", "gene_name": "glipr1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSSCFQLLISACFLLGVFSSEYLFDITDRAFIDECVREHNQNRSSVSPTAANMRYMTWDAALAVTARAWARFCLFKHNIHLREAKRVHPTFTTVGENIWAGAPYSRFTVKSAVFSWVNELKDYNYNNNQCNDKKVCGHYTQVVWADSYKVGCAVQTCPNGVAETHFSNIQGVIFVCNYATAGNFAGRSPYKQGASCSGCGGSDKCERNLCRNTDRDAEQSYNWTPDWDPALSSCGTFCVSVMIIRLISVVLLFVCVHFLQCRYSPFIYD", "length": 269 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0LWZ0-1", "protein_name": "Peptidase inhibitor 15", "gene_name": "Pi15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVMISAVNLVILLSLLCEARTIVLLNFTDSSLPANNFSDIEATLSVPVLSVDIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGACTDNLCFPGAFCIFCVGEDI", "length": 259 }, "evidence": [ { "id": "FB:FBgn0052679", "url": "https://alliancegenome.org/gene/FB:FBgn0052679#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2A5I3-1", "protein_name": "Peptidase inhibitor R3HDML", "gene_name": "R3hdml", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPLLSSIVGLTGLLLWMGHTVGALRMPNTTLVQGRPKNTAVWPLSGLGVPRHRRKRHISARDMSALLDYHNHIRASVHPPAANMEYMVWDEQLARSAEAWATQCIWTHGPSQLMKYVGQNLSIHSGRFRSVVDLVRSWSEEKRHYSFPAPKDCTPHCPWLCSGPVCSHYTQMVWASSSRLGCAINTCSSINVWGNTWQQAVYLVCNYAIKGNWIGEAPYKAGKPCSACPPSYQGNCNSNMCFSGLKSNRLPWV", "length": 253 }, "evidence": [ { "id": "HGNC:16249", "url": "https://alliancegenome.org/gene/HGNC:16249#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-275", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-275#orthology", "database": "AGR" }, { "id": "MGI:3650937", "url": "https://alliancegenome.org/gene/MGI:3650937#orthology", "database": "AGR" }, { "id": "RGD:1305296", "url": "https://alliancegenome.org/gene/RGD:1305296#orthology", "database": "AGR" }, { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" }, { "id": "FB:FBgn0052679", "url": "https://alliancegenome.org/gene/FB:FBgn0052679#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZBM0-1", "protein_name": "R3H domain containing-like", "gene_name": "R3hdml", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPLLYSIVGLAGLLLWMGHTVGALRMPNTTLVQGRPKNIAVWPLSGLGVPRHRRKRHISARDMNALLDYHNHIRASVHPPASNMEYMVWDEQLARAAEAWATQCIWAHGPSQLTKYVGQNLSVHSGRYRSVVDLVKSWSEEKRHYSFPAPKDCTPHCPWLCSGPVCSHYTQMVWASSSRLGCAIHTCSSINVWGSTWQQAVYLVCNYAIKGNWIGEAPYKTGKPCSACPPSYQGNCNSNMCFSGLKSNRLPWV", "length": 253 }, "evidence": [ { "id": "HGNC:16249", "url": "https://alliancegenome.org/gene/HGNC:16249#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-275", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-275#orthology", "database": "AGR" }, { "id": "MGI:3650937", "url": "https://alliancegenome.org/gene/MGI:3650937#orthology", "database": "AGR" }, { "id": "RGD:1305296", "url": "https://alliancegenome.org/gene/RGD:1305296#orthology", "database": "AGR" }, { "id": "FB:FBgn0052679", "url": "https://alliancegenome.org/gene/FB:FBgn0052679#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3ZI91-1", "protein_name": "GLIPR1 like 1", "gene_name": "Glipr1l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALKKKLIFLWTLALYLVASRLPKAFGKVLPRVPTINDPEFKNGFLNSHNEARRKVQPPASNMNQLSWDKSLAKLAKSWTRECKFSHNPCTSKRHGCTKDYDYIGENIYLGKIDARPEDVVFSWYNETKDYNFDDNTCTKTCGHYTQVVWAKTLKIGCAISNCPHLTGYSAGLFVCNYVPAGNFQGSKPYIKGEPCSMCGEKECVNSLCSHTMGRASQQKTCHLLVLGFILQRLI", "length": 235 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" }, { "id": "FB:FBgn0052679", "url": "https://alliancegenome.org/gene/FB:FBgn0052679#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E9PTT8-1", "protein_name": "Cysteine-rich secretory protein 1", "gene_name": "Crisp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSFNSLVHNTKTWFVAAQNFKSYMDVGMAMKLILLLFLAATLTVFVPVVTLRHLKLDRALYNQLITESQTEPQEEIVDTHNAFRRNVSPPARNMLKMSWSSAAAENARILARYCDKSDSDSLERRLPNTFCGENMHMENYPSSWSNVIEIWYNESKYFKYGEWPSTDDDIETYHYTQMVWASSYLIGCDVASCRRQKAATYLYVCHYCHEGNSQDTLNMPYKEGPPCQDCPNNCEDGLCTNPCLYYDEYNNCDKQVKLLGCSHPAVRPFCKAFCLCKTEIK", "length": 281 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "M0R4P4-1", "protein_name": "GLIPR1 like 2", "gene_name": "Glipr1l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKASLPLSVVWRAQSNSIRLRGVLKLWLCELWLLLMSSGLNAKLPLEEDVDFINEYVNLHNELRGTVFPPGVNLRFMTWDVALSRTARAWGKKCVFERNTHLDKVHESHPVFTDIGENMWVGPEKDFTATNAIRSWHEERKSYNYVNDTCIEDEDCSHYIQLVWDHSYKVGCAVTPCAKVGAITYAALFICNYAPGGTLTRRPYQAGQFCSRCTNEEKCIDFLCGNADRDEAAYYQFWYPPWETPRPLVCNRLCFFVLFMRLASLGLCVIIVMIIQNRFPVVLTESPMIMSVEEGVNTEDEIVVEEGEEEIQEEEDEQ", "length": 318 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O43692-1", "protein_name": "Peptidase inhibitor 15", "gene_name": "PI15", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIAISAVSSALLFSLLCEASTVVLLNSTDSSPPTNNFTDIEAALKAQLDSADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGSCTDNLCFPGVTSNYLYWFK", "length": 258 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" }, { "id": "FB:FBgn0052679", "url": "https://alliancegenome.org/gene/FB:FBgn0052679#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "O88205-1", "protein_name": "Cysteine-rich secretory protein 2", "gene_name": "Crisp2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAWFQVMLFVFAVLLPLPPTEGKDPDFATLTTNQIQVQREIIAKHNELRRQVSPPGSNILKMEWNVQAAANAQKWANNCILEHSSTEDRKINIKCGENLYMSTDPTSWRTVIQSWYEENENFVFGVGAKPNSAVGHYTQLVWYSSFKVGCGVAYCPNQDTLKYFYVCHYCPMGNNVMKKSTPYHQGTPCASCPNNCDNGLCTNSCDFEDLLSNCESLKSSAGCKHELLKAKCEATCLCEDKIH", "length": 243 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P12020-1", "protein_name": "Cysteine-rich secretory protein 1", "gene_name": "Crisp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALMLVLLFLAAVLPPSLLQDTTDEWDRDLENLSTTKLSVQEEIINKHNQLRRTVSPSGSDLLRVEWDHDAYVNAQKWANRCIYNHSPLQHRTTTLKCGENLFMANYPASWSSVIQDWYDESLDFVFGFGPKKVGVKVGHYTQVVWNSTFLVACGVAECPDQPLKYFYVCHYCPGGNYVGRLYSPYTEGEPCDSCPGNCEDGLCTNSCEYEDNYSNCGDLKKMVSCDDPLLKEGCRASCFCEDKIH", "length": 246 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P16562-1", "protein_name": "Cysteine-rich secretory protein 2", "gene_name": "CRISP2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALLPVLFLVTVLLPSLPAEGKDPAFTALLTTQLQVQREIVNKHNELRKAVSPPASNMLKMEWSREVTTNAQRWANKCTLQHSDPEDRKTSTRCGENLYMSSDPTSWSSAIQSWYDEILDFVYGVGPKSPNAVVGHYTQLVWYSTYQVGCGIAYCPNQDSLKYYYVCQYCPAGNNMNRKNTPYQQGTPCAGCPDDCDKGLCTNSCQYQDLLSNCDSLKNTAGCEHELLKEKCKATCLCENKIY", "length": 243 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P16563-1", "protein_name": "Cysteine-rich secretory protein 2", "gene_name": "Crisp2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAWFQVMLFVFALLLRSPLTEGKDPDFTSLLTNQLQVQREIVNKHNELRRSVNPTGSDILKMEWSIQATTNAQKWANKCILEHSSKDDRKINIRCGENLYMSTDPTLWSTVIQSWYNENEDFVYGVGAKPNSAVGHYTQLVWYSSFKIGCGIAYCPNQDNLKYFYVCHYCPMGNNVMKKSTPYQQGTPCASCPNNCENGLCTNSCDFEDLLSNCESLKTSAGCKHELLKTKCQATCLCEDKIH", "length": 243 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P48060-1", "protein_name": "Glioma pathogenesis-related protein 1", "gene_name": "GLIPR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRVTLATIAWMVSFVSNYSHTANILPDIENEDFIKDCVRIHNKFRSEVKPTASDMLYMTWDPALAQIAKAWASNCQFSHNTRLKPPHKLHPNFTSLGENIWTGSVPIFSVSSAITNWYDEIQDYDFKTRICKKVCGHYTQVVWADSYKVGCAVQFCPKVSGFDALSNGAHFICNYGPGGNYPTWPYKRGATCSACPNNDKCLDNLCVNRQRDQVKRYYSVVYPGWPIYPRNRYTSLFLIVNSVILILSVIITILVQHKYPNLVLLD", "length": 266 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54107-1", "protein_name": "Cysteine-rich secretory protein 1", "gene_name": "CRISP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEIKHLLFLVAAACLLPMLSMKKKSARDQFNKLVTDLPNVQEEIVNIHNALRRRVVPPASNMLKMSWSEEAAQNARIFSKYCDMTESNPLERRLPNTFCGENMHMTSYPVSWSSVIGVWYSESTSFKHGEWTTTDDDITTDHYTQIVWATSYLIGCAIASCRQQGSPRYLYVCHYCHEGNDPETKNEPYKTGVPCEACPSNCEDKLCTNPCIYYDEYFDCDIQVHYLGCNHSTTILFCKATCLCDTEIK", "length": 249 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P54108-1", "protein_name": "Cysteine-rich secretory protein 3", "gene_name": "CRISP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTLFPVLLFLVAGLLPSFPANEDKDPAFTALLTTQTQVQREIVNKHNELRRAVSPPARNMLKMEWNKEAAANAQKWANQCNYRHSNPKDRMTSLKCGENLYMSSASSSWSQAIQSWFDEYNDFDFGVGPKTPNAVVGHYTQVVWYSSYLVGCGNAYCPNQKVLKYYYVCQYCPAGNWANRLYVPYEQGAPCASCPDNCDDGLCTNGCKYEDLYSNCKSLKLTLTCKHQLVRDSCKASCNCSNSIY", "length": 245 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q03401-1", "protein_name": "Cysteine-rich secretory protein 1", "gene_name": "Crisp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALMLVLFFLAAVLPPSLLQDSSQENRLEKLSTTKMSVQEEIVSKHNQLRRMVSPSGSDLLKMEWNYDAQVNAQQWADKCTFSHSPIELRTTNLRCGENLFMSSYLASWSSAIQGWYNEYKDLTYDVGPKQPDSVVGHYTQVVWNSTFQVACGVAECPKNPLRYYYVCHYCPVGNYQGRLYTPYTAGEPCASCPDHCEDGLCTNSCGHEDKYTNCKYLKKMLSCEHELLKKGCKATCLCEGKIH", "length": 244 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q03402-1", "protein_name": "Cysteine-rich secretory protein 3", "gene_name": "Crisp3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALMLVLFFLAAVLPPSLLQDNSQENSLEKLSTSKKSVQEEIVSKHNQLRRKVSPSGSDLLNMEWNYDAQVNAQQRADKCTFSHSPIELRTTNLKCGENLFMSSYLVPWSSVIQGWYNESKGLIFGVGPKQNVSVVGHHTQVVWKSNLQVACGVAECPENPLRYFYVCRYCPVLNYSGHYPSRPYLAYTARAPCASCPDRCEDGLCTKSCQYKDMSFWCKRLEYVCKHPGLKKRCLATCQC", "length": 241 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q4G1C9-1", "protein_name": "GLIPR1-like protein 2", "gene_name": "GLIPR1L2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEAARPFAREWRAQSLPLAVGGVLKLRLCELWLLLLGSSLNARFLPDEEDVDFINEYVNLHNELRGDVIPRGSNLRFMTWDVALSRTARAWGKKCLFTHNIYLQDVQMVHPKFYGIGENMWVGPENEFTASIAIRSWHAEKKMYNFENGSCSGDCSNYIQLVWDHSYKVGCAVTPCSKIGHIIHAAIFICNYAPGGTLTRRPYEPGIFCTRCGRRDKCTDFLCSNADRDQATYYRFWYPKWEMPRPVVCDPLCTFILLLRILCFILCVITVLIVQSQFPNILLEQQMIFTPEESEAGNEEEEKEEEKKEKEEMEMEIMEMEEEKEEREEEEEETQKEKMEEEEK", "length": 344 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UWM5-1", "protein_name": "GLIPR1-like protein 1", "gene_name": "GLIPR1L1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALKNKFSCLWILGLCLVATTSSKIPSITDPHFIDNCIEAHNEWRGKVNPPAADMKYMIWDKGLAKMAKAWANQCKFEHNDCLDKSYKCYAAFEYVGENIWLGGIKSFTPRHAITAWYNETQFYDFDSLSCSRVCGHYTQLVWANSFYVGCAVAMCPNLGGASTAIFVCNYGPAGNFANMPPYVRGESCSLCSKEEKCVKNLCRTPQLIIPNQNPFLKPTGRAPQQTAFNPFSLGFLLLRIF", "length": 242 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7T141-1", "protein_name": "Peptidase inhibitor 15-A", "gene_name": "pi15a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNENRLAIDILLLCISCGASALAGFSPTASSSLPATNLTDIGFAPPKYLTEAANIPKTRRKRYISQNDMLAILDYHNKVRGKVFPPASNMEYMVWDDTLAKTAEQWASTCIWEHGPRNLLRFLGQNLSVRTGRYRSILQLVKPWHDEVKDYSFPYPRDCNPRCPLKCYGPMCTHYTQMVWATSNKVGCAINTCHNMNVWGSVWKRATYLVCNYSPKGNWIGEAPYKVGVPCSMCPPSYGGSCSNNMCFPAVNSNYLHWFK", "length": 260 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" }, { "id": "FB:FBgn0052679", "url": "https://alliancegenome.org/gene/FB:FBgn0052679#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8BS03-1", "protein_name": "Peptidase inhibitor 15", "gene_name": "Pi15", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIMNSAVSLVILLSLLCEAHTVVLLNPTDSSLPANNFTDTEAALSTPLESADIPKARRKRYISQNDMIAILDYHNQVRGKVFPPAANMEYMVWDENLAKSAEAWAATCIWDHGPSYLLRFLGQNLSVRTGRYRSILQLVKPWYDEVKDYAFPYPQDCNPRCPMRCFGPMCTHYTQMVWATSNRIGCAIHTCQNMNVWGSVWRRAVYLVCNYAPKGNWIGEAPYKVGVPCSSCPPSYGGACTDNLCFPGVTTNYLYWFK", "length": 258 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" }, { "id": "FB:FBgn0052679", "url": "https://alliancegenome.org/gene/FB:FBgn0052679#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BZQ2-1", "protein_name": "Cysteine-rich secretory protein LCCL domain-containing 2", "gene_name": "Crispld2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSCLLNNMVLMGLALLVCGVQAFFLPNTTSLEKLLSKYQHAEPHSRVRRAIPMSDRQEILMLHNKLRGQVYPPASNMEHMTWDEELERSAAAWAHRCLWEHGPAGLLRSIGQNLAVHWGRYRSPGFHVQSWYDEVKDYTYPYPHECTPRCRERCSGPMCTHYTQMVWATTNKIGCAVHTCRNMNVWGDTWENAVYLVCNYSPKGNWIGEAPYKHGRPCSECPSSYGGGCLNNLCHRAEKPHKHKPEVDMMNEVESPPAPEETHVWVQPRVIKTKKTPVINFMTQVVHCDTKMKDSCKGSTCNRYQCPAGCLSNKAKVFGSLFYESSSSICRAAIHYGVIDDRGGLVDVTRNGMVPFFVKSQKNGMESLSKYKPSSSFTVSKVTETAVDCHATVAQLCPFEKPATHCPRIQCPARCGEEPSYWAPVYGTNIYADTSSICKAAVHAGVIVDEVGGYADVMPVDKKKSYVGSLRNGVQSESLNTPQNGNAFRIFAVRQ", "length": 495 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CGD2-1", "protein_name": "Cysteine-rich secretory protein LCCL domain-containing 1", "gene_name": "Crispld1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMCKAQEWLRVTALLFVARAVPAMVVPNATLLEKLLEKYMDEDGEWWTAKQRGKRAITDNDMQSILDLHNKLRSQVYPTASNMEYMTWDVELERSAESWAEMCLWEHGPASLLPSIGQNLGAHWGRYRPPTFHVQAWYDEVRDFSYPYENECDPYCPFRCSGPVCTHYTQVVWATSSRIGCAVNLCHNMNIWGQIWPKAVYLVCNYSPKGNWWGHAPYKHGRPCSACPPSFGGGCRENLCYKEGSDRYYTPREEETNEIERQQSQVHDTHVRTRSDDSDRNDVISTQQMSQIVSCEVRLRDQCKGTTCNRYECPAGCLDSKAKVIGSVHYEMQSSICRAAIHYGIIDNEGGWVDVTRQGRKHYFIKSNRNGIQTIGKYHSANSFTVSKVTVQAVTCETTVEQLCPFHKPASHCPRVYCPRNCMQSNPHYARVIGTRIYSDLSSICRAAVHAGVVRNHGGYVDVMPVDKRKMYTASFQNGIFSESLQNPTGGKAFRVFAVV", "length": 500 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IRL3-1", "protein_name": "Venom allergen-1", "gene_name": "Dmel\\CG32679", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRSPCWIFLLYLVLIIFTFTFAQNYCDPELCPSGRHVACQNSGRFVSGCSGEFVQVDAHIPLILQLHNERRNLIAGGGVSGFPSAVQMATMSWDTTLAQLAAYNALQCRMAHDECRNTNTYRYAGQNLSILFTRSVDVAVFLRQRIAAWFDENRDATSGDMEDYQMRGGPAIGHFTTMVNERNNRVGCAIARFTDANNVQATLLACNYAVTNVVNNPVYRAGTAASECTTGRNSNYPNLCSPNEVYNYNQWSG", "length": 254 }, "evidence": [ { "id": "HGNC:16249", "url": "https://alliancegenome.org/gene/HGNC:16249#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-275", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-275#orthology", "database": "AGR" }, { "id": "MGI:3650937", "url": "https://alliancegenome.org/gene/MGI:3650937#orthology", "database": "AGR" }, { "id": "RGD:1305296", "url": "https://alliancegenome.org/gene/RGD:1305296#orthology", "database": "AGR" }, { "id": "FB:FBgn0052679", "url": "https://alliancegenome.org/gene/FB:FBgn0052679#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9CQ35-1", "protein_name": "GLIPR1-like protein 2", "gene_name": "Glipr1l2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKASLPWSVVWRAQSNYVRLRRVLKLCELWLLLVGSGLNAKLPLEEDVDFINEYVGLHNELRGTVFPPGVNLRFMTWDVALSRTARAWGKKCMYSRNTHLDKLHESHPVFTEIGENMWVGPVEDFTVTTAIRSWHEERKSYSYLNDTCVEDQNCSHYIQLVWDSSYKVGCAVTSCARAGGFTHAALFICNYAPGGTLTRRPYQAGQFCSRCGPGDQCTDYLCSNTVRDEATYYQFWYPPWEKPRPVVCNPMCIFILFLRVASLLLCVIVVLIVQSRFPVILMETPTIISAEEEGKTEVEIVMEEGEGEGEGGEGEGEGEEKEEEEMLEEDEQ", "length": 332 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9CWG1-1", "protein_name": "Glioma pathogenesis-related protein 1", "gene_name": "Glipr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQVILAVIVWMASSVSSSSFTASTLPDITNEDFIKECVQVHNQLRSKVSPPARNMLYMSWDPKLAQIAKAWTKSCEFKHNPQLHSRIHPNFTALGENIWLGSLSIFSVSSAISAWYEEIKHYDFSTRKCRHVCGHYTQVVWADSYKLGCAVQLCPNGANFICDYGPAGNYPTWPYKQGATCSDCPKDDKCLNSLCINPRRDQVSRYYSVDYPDWPIYLRNRYTSLFLIAKSVLLLLSVIITIWVKHKYPNLVLLD", "length": 255 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9DAG6-1", "protein_name": "GLIPR1-like protein 1", "gene_name": "Glipr1l1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALKKKLNFLWTLVLYLIASRLPKAFGKDLPRVPTITDPKFIDAFLNIHNELRRKVQPPAADMNQLFWDQQLAKLAKAWTRECKLAHNPCIKQRYECLEDYDFIGENIYLGRIETQPEDVVINWYNESKYFNFDFNTCSEMCGHYTQVVWAKTVKIGCAVSNCPNLKGFSAGLFVCNYSPAGNFIGFRPYTRGDSCSMCGQKTCENSLCRPMNRKTPHHKAACHVLVLGFILQSLL", "length": 236 }, "evidence": [ { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" }, { "id": "FB:FBgn0052679", "url": "https://alliancegenome.org/gene/FB:FBgn0052679#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H3Y0-1", "protein_name": "Peptidase inhibitor R3HDML", "gene_name": "R3HDML", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPLLPSTVGLAGLLFWAGQAVNALIMPNATPAPAQPESTAMRLLSGLEVPRYRRKRHISVRDMNALLDYHNHIRASVYPPAANMEYMVWDKRLARAAEAWATQCIWAHGPSQLMRYVGQNLSIHSGQYRSVVDLMKSWSEEKWHYLFPAPRDCNPHCPWRCDGPTCSHYTQMVWASSNRLGCAIHTCSSISVWGNTWHRAAYLVCNYAIKGNWIGESPYKMGKPCSSCPPSYQGSCNSNMCFKGLKSNKFTWF", "length": 253 }, "evidence": [ { "id": "HGNC:16249", "url": "https://alliancegenome.org/gene/HGNC:16249#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-275", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-275#orthology", "database": "AGR" }, { "id": "MGI:3650937", "url": "https://alliancegenome.org/gene/MGI:3650937#orthology", "database": "AGR" }, { "id": "RGD:1305296", "url": "https://alliancegenome.org/gene/RGD:1305296#orthology", "database": "AGR" }, { "id": "FB:FBgn0052679", "url": "https://alliancegenome.org/gene/FB:FBgn0052679#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VFY2-1", "protein_name": "SCP domain-containing protein", "gene_name": "Dmel\\CG8483", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMQPSAVLLTTIMIISCEVAFACNGKIIASGITAEERSIILQEHNRLRQIVATGRYPGQPGAENMREIVWDDELAARAQKWADNCQFRHDPHRTINRFTMGQNLAIIWSTAPLDADDGDFPSRIQSWFNEVQKYSFGDAWSPKTGHYSQLVWGETSLVGCGYAEYKDTSKYNKLYVCNYGPGGNVVGYNPYEVGKPSCSTYGMKPSSRYQGLCAAPGSSPAANSVYGANTIETYEYGYNSSPSSQTANNNPPTNNINKSQFSYNQPRPKPVQTINPNPSPFNPQAAVPSASTFGGSSFGSASRGGSHAYTTDPSQSAGRYKHKLEAYRPSAAEFEKSVHKHTILRTYIEQNQQRQDQQQQQQQKEQDQQQQQPEPSSTKKPSRGWSLLTWRG", "length": 392 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090313-275", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-275#orthology", "database": "AGR" }, { "id": "MGI:3650937", "url": "https://alliancegenome.org/gene/MGI:3650937#orthology", "database": "AGR" }, { "id": "FB:FBgn0038126", "url": "https://alliancegenome.org/gene/FB:FBgn0038126#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VY39-1", "protein_name": "Venom allergen-1", "gene_name": "anon-WO0140519.10", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPRLLSKCSVFALWAPAVLLFVLACEKGLAGAQTLIETITTTTPASSGGYCAAALCELYNGTHLVHVPHTACGNNGSFSPACGPEPKLLEMSERRRQLLLDMHNLARSKIASGNLDGYRSAAHMPLLRWDTELEQMAALHAKRCQFAHDKCRNTPRFKFSGQNIGYFWIGREFKSHSRRMKSFVINWFREHQDANQSFIDRYHPHPQGKKIGHFTLLVSDRVNRVGCAGVRFLEPKSNRFQFMLTCNYDYNNIFNEPIYQSGPAGSKCPQHRISEKFPSLCDWRDANNDLDSEESDEDGNTLDNNIPL", "length": 308 }, "evidence": [ { "id": "HGNC:16249", "url": "https://alliancegenome.org/gene/HGNC:16249#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E7EZY0", "url": "https://www.uniprot.org/uniprotkb/E7EZY0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "peptidase inhibitor activity", "id": "GO:0030414", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030414", "evidence": [ { "database": "UniProtKB", "id": "E7EZY0", "url": "https://www.uniprot.org/uniprotkb/E7EZY0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" }, { "start_pos": 46, "end_pos": 48, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EZY0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZY0" }, { "id": "SM00198", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00198" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SCP", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 208, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 123, "end_pos": 125 }, { "start_pos": 46, "end_pos": 48 } ] }, "class_list": [], "section_stats": [ { "table_id": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F0P7-1", "uniprot_ac": "E7F0P7", "uniprot_id": "E7F0P7_DANRE", "mass": { "chemical_mass": 24206.0, "monoisotopic_mass": 24206.0 }, "refseq": { "ac": "NP_001313529", "name": "UPF0193 protein EVG1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313529" }, "gene_names": [ { "name": "si:dkey-43k4.3", "type": "recommended", "evidence": [ { "id": "E7F0P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0P7" } ] }, { "name": "si:dkey-43k4.3", "type": "synonym", "evidence": [ { "id": "NP_001313529", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313529" } ] } ], "protein_names": [ { "name": "UPF0193 protein EVG1 homolog", "type": "synonym", "evidence": [ { "id": "NP_001313529", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313529" } ] }, { "name": "UPF0193 protein EVG1", "type": "synonym", "evidence": [ { "id": "NP_001313529", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313529" }, { "id": "E7F0P7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0P7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.14705609.1, SRR32588729.9223230.1 [ECO:0000332] RNAseq introns :: partial sample support SAMEA3505370, SAMEA3505371 [ECO:0000350] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Dec 9, 2025 this sequence version replaced NP_001313529.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001313529", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313529" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F0P7", "url": "https://www.uniprot.org/uniprotkb/E7F0P7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-43k4.3", "url": "https://www.uniprot.org/uniprotkb/E7F0P7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120215-146", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-146", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000052428", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000052428", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "795882", "url": "https://www.ncbi.nlm.nih.gov/gene/795882", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007914", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007914", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:795882", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795882", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MMAYGKD", "url": "https://omabrowser.org/oma/group/MMAYGKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F0P7", "url": "https://www.orthodb.org/?gene=E7F0P7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28348", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28348", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28348:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28348:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05250", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05250", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001313529", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313529", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7F0P7", "url": "https://www.uniprot.org/uniprotkb/E7F0P7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0P7-1", "url": "https://www.uniprot.org/uniprotkb/E7F0P7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120215-146", "url": "https://zfin.org/ZDB-GENE-120215-146", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMASGSKYKESGIPQYRTDTRQLIKLMMQESRLTDFQQRQINNKLKNGGALPITFYSSPLEPNTPSETRVTRVGTLVGQQQKRSAERCRAGDNYKREQFLPSAARDLEKEKRKLQNLLSTGQKDAGPTHSQRESTERREQPVDRFQEVLDEIEDRRQFLEEMMSLGKGHQYQQLINTEISQKICELEEIDKKRSEELRTPQLTGKEEQ", "length": 208, "header": "tr|E7F0P7-1|E7F0P7_DANRE Isoform 1 of UPF0193 protein EVG1 OS=Danio rerio OX=7955 GN=si:dkey-43k4.3 PE=4 SV=1 CANONICAL=E7F0P7-1" }, "isoforms": [ { "isoform_ac": "E7F0P7-1", "url": "https://www.uniprot.org/uniprotkb/E7F0P7/entry#E7F0P7-1", "sequence": { "sequence": "MMASGSKYKESGIPQYRTDTRQLIKLMMQESRLTDFQQRQINNKLKNGGALPITFYSSPLEPNTPSETRVTRVGTLVGQQQKRSAERCRAGDNYKREQFLPSAARDLEKEKRKLQNLLSTGQKDAGPTHSQRESTERREQPVDRFQEVLDEIEDRRQFLEEMMSLGKGHQYQQLINTEISQKICELEEIDKKRSEELRTPQLTGKEEQ", "length": 208, "header": "tr|E7F0P7-1|E7F0P7_DANRE Isoform 1 of UPF0193 protein EVG1 OS=Danio rerio OX=7955 GN=si:dkey-43k4.3 PE=4 SV=1 CANONICAL=E7F0P7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7F0P7", "url": "https://www.uniprot.org/uniprotkb/E7F0P7" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:795882", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795882", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3L7I2P0-1", "protein_name": "UPF0193 protein EVG1 isoform X2", "gene_name": "C2H22orf23", "tax_id": 10029, "organism": "Cricetulus 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"common_name": "Pig" }, { "uniprot_canonical_ac": "F1N6I1-1", "protein_name": "Chromosome 5 C22orf23 homolog", "gene_name": "C5H22orf23", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASQERVETVTKGTGFWRCPKPTTYTPGTCELLRVMMKESKLTNFQQRHITDTMKRGDTLPLQCNPTSSQRVLPSKQPSSAIYLPPILAARSHLRPAWRCQANGAYSREQFKPQATRDLEMEKRRLQNIFATGKEPEERKRKPHPLRQEDPAPKLDRFEELVKEIQERKEFLADMEALGQGRQYRGIILTEISQKLQEMEDIDHKRSEELRKALATT", "length": 217 }, "evidence": [ { "id": "E7F0P7", "url": "https://omabrowser.org/oma/group/E7F0P7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7FLU1-1", "protein_name": "Similar to human chromosome 22 open reading frame 23", "gene_name": "C7h22orf23", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNPPMASQERVDAVANGTGFHRCRKQAAYTPGTCELLRVMMKESKLTNFQQRHIMDTMKRGAPLPLQCNPTSSQRGSPSKKSAAAIYLPPILATHTHLRPASLCQANGAYSREQFKPQATRDLEKEKRRLQNIFATGKDMEERKKVPHVQQEDPAPELDRFDELVKEIQDRKEFLAAMEALGQGKQYRGIILAEISQKLREMEDIDRRRSKELRKALTTT", "length": 220 }, "evidence": [ { "id": "HGNC:18589", "url": "https://alliancegenome.org/gene/HGNC:18589#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-146", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-146#orthology", "database": "AGR" }, { "id": "MGI:1920774", "url": "https://alliancegenome.org/gene/MGI:1920774#orthology", "database": "AGR" }, { "id": "RGD:1359634", "url": "https://alliancegenome.org/gene/RGD:1359634#orthology", "database": "AGR" }, { "id": "FB:FBgn0035952", "url": "https://alliancegenome.org/gene/FB:FBgn0035952#orthology", "database": "AGR" }, { "id": "E7F0P7", "url": "https://omabrowser.org/oma/group/E7F0P7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BZE7-1", "protein_name": "UPF0193 protein EVG1", "gene_name": "C22orf23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASQKQMEVVTKGTGFRRRPKTITYTPGTCELLRVMMKESKLTNIQQRHIMDIMKRGDALPLQCSPTSSQRVLPSKQIASPIYLPPILAARPHLRPANMCQANGAYSREQFKPQATRDLEKEKQRLQNIFATGKDMEERKRKAPPARQKAPAPELDRFEELVKEIQERKEFLADMEALGQGKQYRGIILAEISQKLREMEDIDHRRSEELRKGLATT", "length": 217 }, "evidence": [ { "id": "HGNC:18589", "url": "https://alliancegenome.org/gene/HGNC:18589#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-146", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-146#orthology", "database": "AGR" }, { "id": "MGI:1920774", "url": "https://alliancegenome.org/gene/MGI:1920774#orthology", "database": "AGR" }, { "id": "RGD:1359634", "url": "https://alliancegenome.org/gene/RGD:1359634#orthology", "database": "AGR" }, { "id": "FB:FBgn0035952", "url": "https://alliancegenome.org/gene/FB:FBgn0035952#orthology", "database": "AGR" }, { "id": "E7F0P7", "url": 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This record is derived from a genomic sequence (NC_133199) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_686681", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_686681" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F1W7", "url": "https://www.uniprot.org/uniprotkb/E7F1W7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-226l10.6", "url": "https://www.uniprot.org/uniprotkb/E7F1W7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-1550", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1550", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000087483", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000087483", "database": "Bgee", "categories": [ "Gene 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"count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F6Y5-1", "uniprot_ac": "E7F6Y5", "uniprot_id": "E7F6Y5_DANRE", "mass": { "chemical_mass": 27624.0, "monoisotopic_mass": 27624.0 }, "refseq": { "ac": "NP_001373576", "name": "methyltransferase-like protein 7A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373576" }, "gene_names": [ { "name": "tmt1a.3", "type": "recommended", "evidence": [ { "id": "E7F6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5" } ] }, { "name": "mettl7a.3", "type": "synonym", "evidence": [ { "id": "NP_001373576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373576" }, { "id": "E7F6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5" } ] }, { "name": "si:ch211-173n18.4", "type": "synonym", "evidence": [ { "id": "NP_001373576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373576" }, { "id": "E7F6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5" } ] }, { "name": "tmt1a.1", "type": "synonym", "evidence": [ { "id": "E7F6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5" } ] }, { "name": "tmt1a.3", "type": "synonym", "evidence": [ { "id": "NP_001373576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373576" } ] } ], "protein_names": [ { "name": "Methyltransferase-like protein 7A", "type": "synonym", "evidence": [ { "id": "E7F6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5/entry#names_and_taxonomy" } ] }, { "name": "methyltransferase like 7A, tandem duplicate 3", "type": "synonym", "evidence": [ { "id": "NP_001373576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373576" } ] }, { "name": "methyltransferase-like protein 7A", "type": "synonym", "evidence": [ { "id": "NP_001373576", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373576" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01035697.1, EH519024.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Aug 29, 2020 this sequence version replaced XP_697500.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001373576", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373576" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F6Y5", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmt1a.3", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061027-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061027-239", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ZFIN:ZDB-GENE-120215-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-64", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR013216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052356", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052356", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569046", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569046", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7F6Y5", "url": "https://www.orthodb.org/?gene=E7F6Y5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45036", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45036", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45036:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45036:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001373576", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373576", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7F6Y5", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F6Y5-1", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061027-239", "url": "https://zfin.org/ZDB-GENE-061027-239", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] }, { "id": "ZDB-GENE-120215-64", "url": "https://zfin.org/ZDB-GENE-120215-64", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSLFLNALAFICKVLTLPLFVGERVGLLSFYKRLYPRLLSSFTIAYNELMNDKKRELFLNLERFQPSKGSLRILEVGCGSGANFEHYPTGSKITCTDPNPHFKTYLEKSMEKNEHLVYDSFIVASGENLQAVEDSSVDAVVCTLVLCTVKDTNKVLQEAKRVLRPGGAFFFLEHVVSDPSTWAYFFQHVLQPFWYYLQDGCEAIRATWKDIDNAGFSDVKLRHIQAPLFFMIKPHIIGYAVK", "length": 242, "header": "tr|E7F6Y5-1|E7F6Y5_DANRE Isoform 1 of Methyltransferase-like protein 7A OS=Danio rerio OX=7955 GN=tmt1a.3 PE=4 SV=1 CANONICAL=E7F6Y5-1" }, "isoforms": [ { "isoform_ac": "E7F6Y5-1", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5/entry#E7F6Y5-1", "sequence": { "sequence": "MSLFLNALAFICKVLTLPLFVGERVGLLSFYKRLYPRLLSSFTIAYNELMNDKKRELFLNLERFQPSKGSLRILEVGCGSGANFEHYPTGSKITCTDPNPHFKTYLEKSMEKNEHLVYDSFIVASGENLQAVEDSSVDAVVCTLVLCTVKDTNKVLQEAKRVLRPGGAFFFLEHVVSDPSTWAYFFQHVLQPFWYYLQDGCEAIRATWKDIDNAGFSDVKLRHIQAPLFFMIKPHIIGYAVK", "length": 242, "header": "tr|E7F6Y5-1|E7F6Y5_DANRE Isoform 1 of Methyltransferase-like protein 7A OS=Danio rerio OX=7955 GN=tmt1a.3 PE=4 SV=1 CANONICAL=E7F6Y5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "E7F6Y5", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] } ], "pathway": [ { "id": "dre:569046", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569046", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A343-1", "protein_name": "Thiol methyltransferase 1A", "gene_name": "Tmt1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTLAILALRLVVCTLSFPLFLLNLIGVWSWVCKRCFPYFLKRFTVMYNEQMATRKRELFSNLQEFAGPSGKLSLLEVGCGTGANFKFYPPGCRVTCIDPNPNFEKFLFKSVAENRHLQFERFLVAVGEDMHQVADGSVDVVVCTLVLCSVKSQEKILREVCRVLRPGGAFYFMEHVADERSTWNYFWQQVLDPVWFLVFDGCNLTRESWKTLEQASFSKLKLQHIQAPLSWALVRPHIYGYAVK", "length": 244 }, "evidence": [ { "id": "MGI:3710670", "url": "https://alliancegenome.org/gene/MGI:3710670#orthology", "database": "AGR" }, { "id": "HGNC:24550", "url": "https://alliancegenome.org/gene/HGNC:24550#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-64#orthology", "database": "AGR" }, { "id": "RGD:1308407", "url": "https://alliancegenome.org/gene/RGD:1308407#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9Q726-1", "protein_name": "Thiol S-methyltransferase TMT1A", "gene_name": "tmt1a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSRFMDACALSFKVLILPLYIAEHVGLLSFFKRVFPMIQYKATDWYNNKMNDKKRELFRNLERFQPPEGSLRILEVGCGSGANFEHYPTGSKITCTDPNPHFKKYLEKSIEKNEHLEYDNFIVASGENLQAVEDSSVDAVVCTLVLCSVKDTNKVLQESKRVLRPGGALFFLEHVVSDPSTWAYFFQHVLEPLWYFFGDGCEVTRATWKHIEAAGFSDVKLHHIQAPLFFMLKPHIVGYAVK", "length": 242 }, "evidence": [ { "id": "RGD:1305205", "url": "https://alliancegenome.org/gene/RGD:1305205#orthology", "database": "AGR" }, { "id": "MGI:3710670", "url": "https://alliancegenome.org/gene/MGI:3710670#orthology", "database": "AGR" }, { "id": "MGI:1918914", "url": "https://alliancegenome.org/gene/MGI:1918914#orthology", "database": "AGR" }, { "id": "HGNC:24550", "url": "https://alliancegenome.org/gene/HGNC:24550#orthology", "database": "AGR" }, { "id": "RGD:1308407", "url": "https://alliancegenome.org/gene/RGD:1308407#orthology", "database": "AGR" }, { "id": "HGNC:28276", "url": "https://alliancegenome.org/gene/HGNC:28276#orthology", "database": "AGR" }, { "id": "SGD:S000002724", "url": "https://alliancegenome.org/gene/SGD:S000002724#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "G3X9G9-1", "protein_name": "Thiol methyltransferase 1A3", "gene_name": "Tmt1a3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTLAVQAMRLVVCIVAFPIFLLNILGMWSWVCKKCFPYFLKRFAMIYNWKMASLKQELFSNLQEFAGPSGKLTLLEVGCGTGANFKFYPPGCRVTCIDPNPNFEKFLFKSVAENRQLQFERFVVAVGEDMHQVTDGSVDVVVCTLVLCSVKNQEKILREVCRVLKPGGAFYFIDHVADERSTWNYFWQQVLARVWFLAFDGCNLTRESWKAIEQANFSKLNLQHIQAPLPLTLVRPHIYGYAVK", "length": 244 }, "evidence": [ { "id": "MGI:3710670", "url": "https://alliancegenome.org/gene/MGI:3710670#orthology", "database": "AGR" }, { "id": "HGNC:24550", "url": "https://alliancegenome.org/gene/HGNC:24550#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061027-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061027-239#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-64#orthology", "database": "AGR" }, { "id": "RGD:1308407", "url": "https://alliancegenome.org/gene/RGD:1308407#orthology", "database": "AGR" }, { "id": "SGD:S000002724", "url": "https://alliancegenome.org/gene/SGD:S000002724#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P38892-1", "protein_name": "Probable S-adenosylmethionine-dependent methyltransferase CRG1", "gene_name": "CRG1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPKTSYLNKNFESAHYNNVRPSYPLSLVNEIMKFHKGTRKSLVDIGCGTGKATFVVEPYFKEVIGIDPSSAMLSIAEKETNERRLDKKIRFINAPGEDLSSIRPESVDMVISAEAIHWCNLERLFQQVSSILRSDGTFAFWFYIQPEFVDFPEALNVYYKYGWSKDYMGKYLNDNQREILLNYGGEKLRSLLSDRFGDIEVTIYSPSDPNASTVTAENSQFLWRAAITLNQFKEFVKSWSIYTSWARDNPSKPDIADIFINELKEICHCEDLNVPLKIEWSTFYYLCRKRE", "length": 291 }, "evidence": [ { "id": "MGI:3710670", "url": "https://alliancegenome.org/gene/MGI:3710670#orthology", "database": "AGR" }, { "id": "MGI:1918914", "url": "https://alliancegenome.org/gene/MGI:1918914#orthology", "database": "AGR" }, { "id": "HGNC:24550", "url": "https://alliancegenome.org/gene/HGNC:24550#orthology", "database": "AGR" }, { "id": "RGD:1308407", "url": "https://alliancegenome.org/gene/RGD:1308407#orthology", "database": "AGR" }, { "id": "HGNC:28276", "url": "https://alliancegenome.org/gene/HGNC:28276#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q06668-1", "protein_name": "Methyltransferase OMS1, mitochondrial", "gene_name": "OMS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MIVFRRFPTCLLHHIRQPASRSLLLESQRRSLSFTSYKYNSSHIDDDKSKKKLKNVFQMNSNRVIRKQKTKEELAKERFEEQLRSPNRFVRWGAIARSEKFSKGMTKYMIGAYVIFLIYGLFFTKKLFAKDKELERLLKKQEEGNANEYEALRIKELKGKLRRRDELKLEEYKKMQEEGIENFDDIRVQNFDQNKLNEQILPARDTTNFYQEKANEYDKAINMEERVIFLGKRRKWLMKHCQGDVLEVSCGTGRNIKYLDMSRINSITFLDSSENMMEITHKKFREKFPKYKKVAFVVGKAENLVDLAEKGKPSLENEKENQVKYDTIVEAFGLCSHEDPVKALNNFGKLLKPDGRIILLEHGRGQYDFINKILDNRAERRLNTWGCRWNLDLGEVLDDSDLELVEEKRTHLGTTWCIVAKRKGDVKKKDELGFVEKYLQSSIRKRMESFEKKDDMASKKELEPVPPVSKS", "length": 471 }, "evidence": [ { "id": "RGD:1305205", "url": "https://alliancegenome.org/gene/RGD:1305205#orthology", "database": "AGR" }, { "id": "MGI:3710670", "url": "https://alliancegenome.org/gene/MGI:3710670#orthology", "database": "AGR" }, { "id": "MGI:1918914", "url": "https://alliancegenome.org/gene/MGI:1918914#orthology", "database": "AGR" }, { "id": "HGNC:24550", "url": "https://alliancegenome.org/gene/HGNC:24550#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061027-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061027-239#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-64#orthology", "database": "AGR" }, { "id": "SGD:S000002724", "url": "https://alliancegenome.org/gene/SGD:S000002724#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q562C4-1", "protein_name": "Thiol S-methyltransferase TMT1B", "gene_name": "Tmt1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDVLVPLLQLLVLLLTLPLHLLALLGCWQPICKTYFPYLMATLTARSYKKMESKKRELFSQIKDLKGTSNEVTLLELGCGTGANFQFYPPGCKVTCVDPNPNFEKFLTKSMAENRHLQYERFIVAYGENMKQLADSSMDVVVCTLVLCSVQSPRKVLQEVQRVLKPGGLLFFWEHVSEPQGSQALLWQRVLEPTWKHIGDGCHLTRETWKDIEKAQFSEVQLEWQPPPFKWLPVGPHIMGKAVK", "length": 244 }, "evidence": [ { "id": "RGD:1305205", "url": "https://alliancegenome.org/gene/RGD:1305205#orthology", "database": "AGR" }, { "id": "MGI:1918914", "url": "https://alliancegenome.org/gene/MGI:1918914#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061027-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061027-239#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-64#orthology", "database": "AGR" }, { "id": "HGNC:28276", "url": "https://alliancegenome.org/gene/HGNC:28276#orthology", "database": "AGR" }, { "id": "SGD:S000002724", "url": "https://alliancegenome.org/gene/SGD:S000002724#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6UX53-1", "protein_name": "Thiol S-methyltransferase TMT1B", "gene_name": "TMT1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDILVPLLQLLVLLLTLPLHLMALLGCWQPLCKSYFPYLMAVLTPKSNRKMESKKRELFSQIKGLTGASGKVALLELGCGTGANFQFYPPGCRVTCLDPNPHFEKFLTKSMAENRHLQYERFVVAPGEDMRQLADGSMDVVVCTLVLCSVQSPRKVLQEVRRVLRPGGVLFFWEHVAEPYGSWAFMWQQVFEPTWKHIGDGCCLTRETWKDLENAQFSEIQMERQPPPLKWLPVGPHIMGKAVK", "length": 244 }, "evidence": [ { "id": "RGD:1305205", "url": "https://alliancegenome.org/gene/RGD:1305205#orthology", "database": "AGR" }, { "id": "MGI:1918914", "url": "https://alliancegenome.org/gene/MGI:1918914#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061027-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061027-239#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-64#orthology", "database": "AGR" }, { "id": "HGNC:28276", "url": "https://alliancegenome.org/gene/HGNC:28276#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9DD20-1", "protein_name": "Thiol S-methyltransferase TMT1B", "gene_name": "Tmt1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDALVLFLQLLVLLLTLPLHLLALLGCWQPICKTYFPYFMAMLTARSYKKMESKKRELFSQIKDLKGTSGNVALLELGCGTGANFQFYPQGCKVTCVDPNPNFEKFLTKSMAENRHLQYERFIVAYGENMKQLADSSMDVVVCTLVLCSVQSPRKVLQEVQRVLRPGGLLFFWEHVAEPQGSRAFLWQRVLEPTWKHIGDGCHLTRETWKDIERAQFSEVQLEWQPPPFRWLPVGPHIMGKAVK", "length": 244 }, "evidence": [ { "id": "RGD:1305205", "url": "https://alliancegenome.org/gene/RGD:1305205#orthology", "database": "AGR" }, { "id": "MGI:1918914", "url": "https://alliancegenome.org/gene/MGI:1918914#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061027-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061027-239#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-64#orthology", "database": "AGR" }, { "id": "HGNC:28276", "url": "https://alliancegenome.org/gene/HGNC:28276#orthology", "database": "AGR" }, { "id": "SGD:S000002724", "url": "https://alliancegenome.org/gene/SGD:S000002724#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H8H3-1", "protein_name": "Thiol S-methyltransferase TMT1A", "gene_name": "TMT1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELTIFILRLAIYILTFPLYLLNFLGLWSWICKKWFPYFLVRFTVIYNEQMASKKRELFSNLQEFAGPSGKLSLLEVGCGTGANFKFYPPGCRVTCIDPNPNFEKFLIKSIAENRHLQFERFVVAAGENMHQVADGSVDVVVCTLVLCSVKNQERILREVCRVLRPGGAFYFMEHVAAECSTWNYFWQQVLDPAWHLLFDGCNLTRESWKALERASFSKLKLQHIQAPLSWELVRPHIYGYAVK", "length": 244 }, "evidence": [ { "id": "MGI:3710670", "url": "https://alliancegenome.org/gene/MGI:3710670#orthology", "database": "AGR" }, { "id": "HGNC:24550", "url": "https://alliancegenome.org/gene/HGNC:24550#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061027-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061027-239#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-64#orthology", "database": "AGR" }, { "id": "RGD:1308407", "url": "https://alliancegenome.org/gene/RGD:1308407#orthology", "database": "AGR" }, { "id": "SGD:S000002724", "url": "https://alliancegenome.org/gene/SGD:S000002724#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "methyltransferase activity", "id": "GO:0008168", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008168", "evidence": [ { "database": "UniProtKB", "id": "E7F6Y5", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5" } ], "pmid": "" }, { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "E7F6Y5", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F6Y5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F6Y5" }, { "id": "PF08241", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08241" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase type 11", "eco_id": "ECO_0000259", "start_pos": 74, "end_pos": 171, "start_aa": "Leu", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E9QEM8-1", "uniprot_ac": "E9QEM8", "uniprot_id": "E9QEM8_DANRE", "mass": { "chemical_mass": 71348.0, "monoisotopic_mass": 71348.0 }, "refseq": { "ac": "NP_001418354", "name": "piggyBac transposable element derived 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418354" }, "gene_names": [ { "name": "pgbd4", "type": "recommended", "evidence": [ { "id": "E9QEM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QEM8" } ] }, { "name": "pgbd4", "type": "synonym", "evidence": [ { "id": "NP_001418354", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418354" } ] }, { "name": "si:ch73-353p21.4", "type": "synonym", "evidence": [ { "id": "NP_001418354", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418354" }, { "id": "E9QEM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QEM8" } ] } ], "protein_names": [ { "name": "PiggyBac transposable element derived 4", "type": "synonym", "evidence": [ { "id": "E9QEM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QEM8/entry#names_and_taxonomy" } ] }, { "name": "piggyBac transposable element derived 4", "type": "synonym", "evidence": [ { "id": "NP_001418354", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418354" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01016840.1, SRR32588721.4471979.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476754 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001418354", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418354" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QEM8", "url": "https://www.uniprot.org/uniprotkb/E9QEM8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "pgbd4", "url": "https://www.uniprot.org/uniprotkb/E9QEM8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-417", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-417", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "101886287", "url": "https://www.ncbi.nlm.nih.gov/gene/101886287", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029526", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029526", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101886287", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886287", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E9QEM8", "url": "https://www.orthodb.org/?gene=E9QEM8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46599", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46599", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46599:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46599:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13843", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13843", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001418354", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001418354", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E9QEM8", "url": "https://www.uniprot.org/uniprotkb/E9QEM8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QEM8-1", "url": "https://www.uniprot.org/uniprotkb/E9QEM8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-417", "url": "https://zfin.org/ZDB-GENE-091204-417", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDKTNGQTTEESVDASNTEESDEALESSCESSSSNADSDEEVYLKTLDELWSPDGSDEEWCPEVTPQRKKRKHQSSVSPSPAKSHRSASPGSAQSAKGKGKHKGRMRQHVSTSNSILESKWKSVDEPDIEPPQLLFKPKRTPGPQLISTASFSVLQYFELFFSQPVMQKIVDHSNIFGAMRHEARKRKWKDITVADLKSFIAMVIYMGIVKCFNLQDYWRMSDVYSLPYPAKIMSRIKFLTISWALHLSDPKVDAENDKKRGTPQYDPLCKIKPLYQDIRDACKASFHPHQNISIDERMVASKARHGLIQYISEPTKWGYKLFVLADSLCAYTWDFFIYEGKVKTEQRKGISYDSVMALIDERVLGTGYKLFVDNFYTSPTLFRDLLSKKIGACGTIRPNRINHTETEAPRGNIRWFREDGLLFVEWKDKRDVLMCSTFHKAYNGDYIKRNVKGKGSVWGVKEFPVPGAVLDYNKYKGGEDVSNALIGYYTVFRQTKKWYRSFFYHFVDIAIVNAFILHQQMAKSKNQKAMTQKAFRETLITELTGIGSASTSTPKAPVPTTGLHLPRYISGDSTVGRRKCKLCQLKTPMICATCDVALCLVSNRNCYVKWHEQDSDSEEDDDDDD", "length": 626, "header": "tr|E9QEM8-1|E9QEM8_DANRE Isoform 1 of PiggyBac transposable element derived 4 OS=Danio rerio OX=7955 GN=pgbd4 PE=1 SV=1 CANONICAL=E9QEM8-1" }, "isoforms": [ { "isoform_ac": "E9QEM8-1", "url": "https://www.uniprot.org/uniprotkb/E9QEM8/entry#E9QEM8-1", "sequence": { "sequence": "MDKTNGQTTEESVDASNTEESDEALESSCESSSSNADSDEEVYLKTLDELWSPDGSDEEWCPEVTPQRKKRKHQSSVSPSPAKSHRSASPGSAQSAKGKGKHKGRMRQHVSTSNSILESKWKSVDEPDIEPPQLLFKPKRTPGPQLISTASFSVLQYFELFFSQPVMQKIVDHSNIFGAMRHEARKRKWKDITVADLKSFIAMVIYMGIVKCFNLQDYWRMSDVYSLPYPAKIMSRIKFLTISWALHLSDPKVDAENDKKRGTPQYDPLCKIKPLYQDIRDACKASFHPHQNISIDERMVASKARHGLIQYISEPTKWGYKLFVLADSLCAYTWDFFIYEGKVKTEQRKGISYDSVMALIDERVLGTGYKLFVDNFYTSPTLFRDLLSKKIGACGTIRPNRINHTETEAPRGNIRWFREDGLLFVEWKDKRDVLMCSTFHKAYNGDYIKRNVKGKGSVWGVKEFPVPGAVLDYNKYKGGEDVSNALIGYYTVFRQTKKWYRSFFYHFVDIAIVNAFILHQQMAKSKNQKAMTQKAFRETLITELTGIGSASTSTPKAPVPTTGLHLPRYISGDSTVGRRKCKLCQLKTPMICATCDVALCLVSNRNCYVKWHEQDSDSEEDDDDDD", "length": 626, "header": "tr|E9QEM8-1|E9QEM8_DANRE Isoform 1 of PiggyBac transposable element derived 4 OS=Danio rerio OX=7955 GN=pgbd4 PE=1 SV=1 CANONICAL=E9QEM8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 561, "start_aa": "Thr", "end_pos": 561, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr561", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "A fish-specific transposable element shapes the repertoire of p53 target genes in zebrafish.", "journal": "PLoS ONE", "date": "2012", "authors": "Micale Lucia, Loviglio Maria Nicla, Manzoni Marta, Fusco Carmela, Augello Bartolomeo, Migliavacca Eugenia, Cotugno Grazia, Monti Eugenio, Borsani Giuseppe, Reymond Alexandre, Merla Giuseppe", "evidence": [ { "database": "UniProtKB", "id": "E9QEM8", "url": "https://www.uniprot.org/uniprotkb/E9QEM8" } ], "reference": [ { "type": "PubMed", "id": "23118857", "url": "https://glygen.org/publication/PubMed/23118857" } ] }, { "title": "Genome wide association and genomic prediction for growth traits in juvenile farmed Atlantic salmon using a high density SNP array.", "journal": "BMC Genomics", "date": "2015", "authors": "Tsai Hsin-Yuan, Hamilton Alastair, Tinch Alan E, Guy Derrick R, Gharbi Karim, Stear Michael J, Matika Oswald, Bishop Steve C, Houston Ross D", "evidence": [ { "database": "UniProtKB", "id": "E9QEM8", "url": "https://www.uniprot.org/uniprotkb/E9QEM8" } ], "reference": [ { "type": "PubMed", "id": "26582102", "url": "https://glygen.org/publication/PubMed/26582102" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "E9QEM8", "url": "https://www.uniprot.org/uniprotkb/E9QEM8" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Gene Characterization of Nocturnin Paralogues in Goldfish: Full Coding Sequences, Structure, Phylogeny and Tissue Expression.", "journal": "Int. J. Mol. Sci.", "date": "2023", "authors": "Madera Diego, Alonso-G\u00f3mez Aitana, Delgado Mar\u00eda Jes\u00fas, Valenciano Ana Isabel, Alonso-G\u00f3mez \u00c1ngel Luis", "evidence": [ { "database": "UniProtKB", "id": "E9QEM8", "url": "https://www.uniprot.org/uniprotkb/E9QEM8" } ], "reference": [ { "type": "PubMed", "id": "38203224", "url": "https://glygen.org/publication/PubMed/38203224" } ] } ], "pathway": [ { "id": "dre:101886287", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101886287", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1NED1-1", "protein_name": "Uncharacterized protein LOC100037365", "gene_name": "", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLRNKHDETPQVDADREEEYHFSSEEEQEDDIEDDEYEEETADSSDDCDNDSEQIPVAKRAKTVSWRTERDADKLPKNLRFQPAREPGPQLSPADPLNPLSLFKLFFSKSVVSNLCKNTNAQAARAMAKQCKYPWTDVSVEELYHYIGLIFYMDVVRMYSVADYWRQDPFFSVPFPSTVMSMDRYHAILCNLHLSDPNADENDGDTLFKVKSLMDSIRQACSAHYQPRRNVVVSERFVLRKVKPVIKAKLGFRFFVLIDSSNGYTADVSVYKTSFPPRPGFSYDTVMSLLDAKALGSGYHVYMDDFYTTPKLMKDLFALKFGACGMYRDQRKDFPRNKSNPLTEKSARGSYRWIRDGPVVFVKWMDRPEVSICSTIHQAYTGEHVERKVRRQGSRKTKSIPCPAPVSAYSQHIVEVDPFDQLLQYYIMHYNSLKWYKKVFLQFLDIAAANAFILHKEQGGKLTHKKFMDQLIEELCSVSEEVPEQSSIQVEHLPVSGALLESHTATTGRQACSQCKKQDIRQLTPWKCQACHVFLCVEVDRNRFLDWHKNIACSGL", "length": 556 }, "evidence": [ { "id": "HGNC:19401", "url": "https://alliancegenome.org/gene/HGNC:19401#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB13ABV5-1", "protein_name": "Wu:fc11c11", "gene_name": "fc11c11", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MDETNENRTDECVEDSSEDEDETLASEESSDESAASSADSGEEMFLEAMDPVLNGFIDDSDEDWSPEVTPLKKKRKGPSSVSPSPAKSRRTASPGSARSAKGRKGSVRRSLPFSCSILESKWKSVDEPDIEPPQLLFKPKRTPGPQLISTSSCSVLQYFQLFFSKSVMQKIVDHSNIYASMHTNEKKKPWKNITIKDLKSFIAMVIYMGIVKCFNLTDYWKRTDFYSLPYPARIMSCRKFLSMCWALHLSNPKVDAENDKKKGTPQYDRLCKIKPLYQDIRDACKASFHPHQNISIDERMVASKARHGLIQYMKNKPTKWGYKLFVLADSLCAYTWDFFIYEGKVKTEQRKGISYDSVMALIDERVLGTGYKLFVDNFYTSPTLFRDLLSKKIGACGTIRANRIGHSKTPAPRGNIRWFREDGLLFVEWKDKRDVLMCSTFHKAYNGDYIKRNVKGKGGVWTPQDFPVPAAVLDYNKHMGGVDVSDALIGYYTVLHKTKKWYRSFFYHFVDIAVVNAFILHQQMAKSKNQKAMTQKVFRETLVAELAGIRAGYPPAREAAIASTDNHLPKYIKGDSTFGRRKCKLCTHKTPITCVTCQVHLCFVPKRDCYTKWHESGNSDSDTE", "length": 624 }, "evidence": [ { "id": "HGNC:19401", "url": "https://alliancegenome.org/gene/HGNC:19401#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q96DM1-1", "protein_name": "PiggyBac transposable element-derived protein 4", "gene_name": "PGBD4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSNPRKRSIPMRDSNTGLEQLLAEDSFDESDFSEIDDSDNFSDSALEADKIRPLSHLESDGKSSTSSDSGRSMKWSARAMIPRQRYDFTGTPGRKVDVSDITDPLQYFELFFTEELVSKITRETNAQAALLASKPPGPKGFSRMDKWKDTDNDELKVFFAVMLLQGIVQKPELEMFWSTRPLLDTPYLRQIMTGERFLLLFRCLHFVNNSSISAGQSKAQISLQKIKPVFDFLVNKFSTVYTPNRNIAVDESLMLFKGPLAMKQYLPTKRVRFGLKLYVLCESQSGYVWNALVHTGPGMNLKDSADGLKSSRIVLTLVNDLLGQGYCVFLDNFNISPMLFRELHQNRTDAVGTARLNRKQIPNDLKKRIAKGTTVARFCGELMALKWCDGKEVTMLSTFHNDTVIEVNNRNGKKTKRPRVIVDYNENMGAVDSADQMLTSYPSERKRHKVWYKKFFHHLLHITVLNSYILFKKDNPEHTMSHINFRLALIERMLEKHHKPGQQHLRGRPCSDDVTPLRLSGRHFPKSIPATSGKQNPTGRCKICCSQYDKDGKKIRKETRYFCAECDVPLCVVPCFEIYHTKKNY", "length": 585 }, "evidence": [ { "id": "HGNC:19401", "url": "https://alliancegenome.org/gene/HGNC:19401#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-417", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-417#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VHL1-1", "protein_name": "PiggyBac transposable element-derived protein domain-containing protein", "gene_name": "Dmel\\CG9839", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSSGRKRKQQLKPRQDDHRSPVKRRSVDIKSEPLDGYPALADYDLSTADIKPDLTELQLQLVAEQQAASNTIRLELEQQESDSDEDGYSELDYQAEDVFCQDDMDDYDPDWSSQQTGSRLLFKFPIQQSGLKFGQRFQGPQHYFNQVLGNRSKFFSSLAQSCNLKGGELKSNPTTAEEMEIFMALSLLMCDLKLEHLSDYWSTNMFYGLVGFSGKIPLERYQQLLHCLNFDAPQLQAGRAKVKNSLLLDFINERMEEIYICGQQLVLNEPITLWKGALRYQDELPNKFRTNALLLHMLTEQSGLVVKILPEIVRKEDAPAWVRNSRQLVEHRNKIVLKLMEGYHGGRTVYTSKFYGSYGLAQELAKKSTYCTGLLDRNRYGNSKALVHQRLDSNSISTSYATSLMMAKWRRRAKSLYCFSSDCLAIYSKEMAMQKTNAKPKLIQELEFQLRPGNDGRHHLIHYQAACKELKANIKLTIFLLNILVYNAYLLYFANGQNARVGHLKSYSEFRVIIIKSLLREEVTNEPVTSIQKPETYERSKNKPVPEPRLKTILHEPMLIQQNGKPAKKNCRYCHKGGMLQFSRYMCNTCPDKPGLCQEPCFLLWHEQLKKVIRQTIGRSE", "length": 622 }, "evidence": [ { "id": "HGNC:19401", "url": "https://alliancegenome.org/gene/HGNC:19401#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 403, "end_pos": 405, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E9QEM8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QEM8" }, { "id": "PF13843", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13843" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PiggyBac transposable element-derived protein", "eco_id": "ECO_0000259", "start_pos": 156, "end_pos": 516, "start_aa": "Gln", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 561 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 292, "end_pos": 294 }, { "start_pos": 403, "end_pos": 405 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "F1QC22-1", "uniprot_ac": "F1QC22", "uniprot_id": "F1QC22_DANRE", "mass": { "chemical_mass": 50288.0, "monoisotopic_mass": 50288.0 }, "refseq": { "ac": "NP_001083040", "name": "zinc finger protein 1157", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083040" }, "gene_names": [ { "name": "znf1157", "type": "recommended", "evidence": [ { "id": "F1QC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QC22" } ] }, { "name": "zgc:162358", "type": "synonym", "evidence": [ { "id": "NP_001083040", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083040" }, { "id": "F1QC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QC22" } ] }, { "name": "znf1157", "type": "synonym", "evidence": [ { "id": "NP_001083040", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083040" } ] } ], "protein_names": [ { "name": "Zinc finger protein 1157", "type": "synonym", "evidence": [ { "id": "F1QC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QC22/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 1157", "type": "synonym", "evidence": [ { "id": "NP_001083040", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083040" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR26395028.334719.1, SRR26395017.655257.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01765705, SAMN06350654 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On Aug 27, 2018 this sequence version replaced NP_001083040.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. The previous version of this record, NM_001089571.1, has multiple differences relative to the updated version. These differences are a result of the use of a different strain (Singapore) in the previous version.", "evidence": [ { "database": "RefSeq", "id": "NP_001083040", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083040" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "F1QC22", "url": "https://www.uniprot.org/uniprotkb/F1QC22#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "F1QC22", "url": "https://www.uniprot.org/uniprotkb/F1QC22" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "znf1157", "url": "https://www.uniprot.org/uniprotkb/F1QC22", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070424-89", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-89", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100038791", "url": "https://www.ncbi.nlm.nih.gov/gene/100038791", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050589", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050589", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100038791", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100038791", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR24404", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24404:SF111", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24404:SF111", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001083040", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001083040", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "F1QC22", "url": "https://www.uniprot.org/uniprotkb/F1QC22", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "F1QC22-1", "url": "https://www.uniprot.org/uniprotkb/F1QC22-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070424-89", "url": "https://zfin.org/ZDB-GENE-070424-89", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSDPEPCRIKQEETEELIDVIVKEEREELSEDEEKHQIKSDLEFQSVTEDSFLIKTTAVKAFTCTQCGKSFGNKSNLNRHMRIHTGEKPYKCSHCDKRFIHSGNLKIHERIHTGRSLFTCTYCGKSFRQSYLHQHMLIHTGEKTHKCDQCHKTFLRPSDLKTHLRVHTKEKPYSCPECGKGFSQHSSLSLHQKIHTGVREFVCRECKKNFITAGDLKKHQMIHTGEKPYKCSHCDKRFSQLRPMKTHERIHTGEKPLSCSLCGKSFNQSSNLFRHMMIHTGERPHRCDQCGKTFMRTSELKRHLRFHTKEKPYSCSECGKSFTMKSHCQAHQKIHTGVREFVCFECGKSFIRAEHLKQHQMTHTGEKPYACSHSLCNKAFRNPAHLKTHERTHTGEKPFTCTQCGKSFSRSTCLHRHTMRNHTNLINAAKHN", "length": 432, "header": "tr|F1QC22-1|F1QC22_DANRE Isoform 1 of Zinc finger protein 1157 OS=Danio rerio OX=7955 GN=znf1157 PE=3 SV=1 CANONICAL=F1QC22-1" }, "isoforms": [ { "isoform_ac": "F1QC22-1", "url": "https://www.uniprot.org/uniprotkb/F1QC22/entry#F1QC22-1", "sequence": { "sequence": "MSDPEPCRIKQEETEELIDVIVKEEREELSEDEEKHQIKSDLEFQSVTEDSFLIKTTAVKAFTCTQCGKSFGNKSNLNRHMRIHTGEKPYKCSHCDKRFIHSGNLKIHERIHTGRSLFTCTYCGKSFRQSYLHQHMLIHTGEKTHKCDQCHKTFLRPSDLKTHLRVHTKEKPYSCPECGKGFSQHSSLSLHQKIHTGVREFVCRECKKNFITAGDLKKHQMIHTGEKPYKCSHCDKRFSQLRPMKTHERIHTGEKPLSCSLCGKSFNQSSNLFRHMMIHTGERPHRCDQCGKTFMRTSELKRHLRFHTKEKPYSCSECGKSFTMKSHCQAHQKIHTGVREFVCFECGKSFIRAEHLKQHQMTHTGEKPYACSHSLCNKAFRNPAHLKTHERTHTGEKPFTCTQCGKSFSRSTCLHRHTMRNHTNLINAAKHN", "length": 432, "header": "tr|F1QC22-1|F1QC22_DANRE Isoform 1 of Zinc finger protein 1157 OS=Danio rerio OX=7955 GN=znf1157 PE=3 SV=1 CANONICAL=F1QC22-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "F1QC22", "url": "https://www.uniprot.org/uniprotkb/F1QC22" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100038791", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100038791", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZKU3-1", "protein_name": "Zinc finger protein 709-like", "gene_name": "LOC108348302", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTVVQDLVSFEDVAVHFTQEEWALLDPSQKNLYRDVMLETCRSLAAIGYKWEEQNVEDDCKNVGRIQRHVISDSEYLPEEQEGYGSKPYDSSSLPSIQGYTGAHTVNGPCECEVCLKSFGFPSTFGMYHQPHSGQNFCDYKECGKASVYHSSLYTHGGTHSIRKCYSCNQCGKVLSSSSSLQRHERIHTGERPYKCQQCGKALSSSTSLQRHERIHTGERPYKCQQCGKAFRCHSALQLHERIHTGEKPYECQQCGKAFTCHSYLRLHERTHTGEKPYECKQCGKAFRCQTSYHRHKIIHGGETFYECKQCSRLFIYPSLLQMHERTHTSERPYKCKECGKSFLYPSLLQMHERTHTGEKPYECKQCGTAFRHHSSLRLHERTHTGEKPYECQQCGKAFTRHTSLRLHEITHTGEKPYKCKECGKAFRHHSSLRLHGRNHSGEKPYECKQCDKAFIRYSYLRLHERTHTGEKPYECKQCGKAFSRHSSFQRHKSIHTVENPYECQQYLIPLPLFPPSTSDNSFW", "length": 524 }, "evidence": [ { "id": "HGNC:12920", "url": "https://alliancegenome.org/gene/HGNC:12920#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A2ART0-1", "protein_name": "Predicted gene 14391", "gene_name": "Gm6710", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLVTYDDVQVNFTQDEWALLDPSQKSLYKDVMLETYRNLTAIGYIWEEHTIEDHFQTSRSHGRHERSCSAEQPSEFIQCGKAFAYESGRQRHQIKHNGEKHHDCNQCGKDFRTWNVLQIHKRTHTGEKPYDCKQCGKVFARSCHLQIHNRTHAGEKQYECNQCGKALKRRSDLQIHKRTHTGEKPYECNQCGKAFASSGDLQQHKRTHTGEKPYECKQCGKAFSECSHLRIHKRTHTGEKPYECKQCGKAFAHSSHLHKHERTHTGDKPYECNQCGKAFAVIYTLQMHKRTHTGDKPYECNQCGKAFAVIYTLQMHKRTHTGDKPYECNQCGKAFAVIYTLQRHKQTHTGEKPYKCKQCGKAFTRSCHLRIHKRTHTGEKPYECNQCGKAFARSGDLQKHKRTHTGEKPYECKQCGKAFAHSSHLHKHERTHTGDKPYECNQCGKAFAESSTLQIHNRTHTGEKPYECNQCGKAFITRRVLQIHKRTHTGEKPYECKQCGKAFASSSDLQKHKRTHSGAKPYECKQCGKAFAQSSHLRIHKQTHTGERPYECN", "length": 554 }, "evidence": [ { "id": "HGNC:12920", "url": "https://alliancegenome.org/gene/HGNC:12920#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ART2-1", "protein_name": "Zinc finger protein 967", "gene_name": "Zfp968", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRDSTGCCERRLVKLRTPNMDLVTYDDVHVNFTQEEWALLDASQKSLYKGVMVETYRNLTAIGYSWEEHTIEDHFQTSRSHGRHERRSSAEQHSEFIPCGKAFAYQSRSQRHVRIHNGEKHYECNQCGKDFGTRSVLQRLKRTHTGEKPYECNHYGKAFAESSTLQIHKRKHTGEKPYECNHCVKAFAKMSKLQIHKRIHTGEKPYECKQCGKAFTQSSHLGIHKRTHTGEKPYECKQCGKAFTRSSTLQTHKQTHTGEKPYECKQCDKAFVRRGELQIHKRTHTGEKPYECKQCGKAFAQSGTLQIHKRTHTGEKPYECKQCGKAFAHSSTLQIHKRTHTGEKPYECKQCDKAFVKRGELQIHKQTHTGEKPYECKQCGKAFAQSGTLQVHERTHTGEKPFECNQCGKAFVQCIALRIHERTHTGEKPYECKQCGKAFAHSNTLQIHKRTHTGEKPYECKQCGKAFAHSSTLQIHKQTHTGEKP", "length": 485 }, "evidence": [ { "id": "HGNC:12920", "url": "https://alliancegenome.org/gene/HGNC:12920#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2ART4-1", "protein_name": "Predicted gene 14434", "gene_name": "Gm4631", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLVTYDDVHVNFTQDEWALLDPSQKSLYKGVMLETYKNLTAIGYIWEEHTIEDHFQTSRSHGRHERSCSAEQPSEFIQCGKAFAYESGRQRHQIKHNGEKHHDCNQCGKDFRTWNVLQIHKRTHTGEKPYDCKQCGKVFARSCHLQIHNRTHAGEKQYECNQCGKAFKRRINLQIHKRTHTGEKPYECNQCGKAFASSGELQKHKRTHTGEKPYECKQCGKAFSQSSHLRIHKRTHTGEKPYECNQCGKAFARSGDLQKHKRTHTGEKPYECKQCGKAFAHSSHLHKHERTHTGDKPYECKQCGKAFAVIYTLQMHKRTHTGDKPYECKQCGKAFAVIYTLQMHKRTHTGEKPYKCKQCGKAFARSCHLRIHKRTHTGEKPYECNQCGKAFAESSTLQIHNRTHTGEKPYECNQCGKAFITRRVLQIHKRTHTGEKPYECNQCGKAFARSCDLQKHKRTHTGEKPYECNHCGKAFAQSSSLRIHKRTYTGERQYECN", "length": 498 }, "evidence": [ { "id": "HGNC:12920", "url": "https://alliancegenome.org/gene/HGNC:12920#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2AW67-1", "protein_name": "Predicted gene 14325", "gene_name": "Gm14325", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLITYDDVHVNFTQEEWALLDPSQKSLYKGVMLETYRNLTAIGYIWEEHTIEDHLQTSRSHGRHERSCSAEQPSEFIQCGKAFAYESGRQRHQIKHTGEKHHDCNQCGKDFRTWNVLQIHKRTHTGEKPYDCKQCGKAFARSCHLRIHNRTHAGEKQYECNQCGKAFKRRSDLQIHKRTHTGEKPYECKQCGKAFVSSGELQKHKRTHTGEKPYECKQCGKAFSQSSHLRIHKRTHTGEKPYECNQCGKAFARSGDLQKHKRTHTGEKPYECKQCGKAFAHSSHLHIHERRHTGDKPYECKQCGKAFAVFYTLQMHKRTHTGDKPYECKQCGKAFTVIYTLQMHKQTHTGEKPYECKQCGKTFSQSRHLRIHKRTHTGEKPYECNQCGKAFARSGDQQEHKRTHTGEKPYECNQCGKAFIRRRVLQIHKRTHTGEKPYECKQCGKAFASSSDLQKHKRTHSGEKPYECKQCGKAFAQSSHLRIHKQTHTGERPYECN", "length": 498 }, "evidence": [ { "id": "HGNC:12920", "url": "https://alliancegenome.org/gene/HGNC:12920#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "A2BFG8-1", "protein_name": "Zinc finger protein 971", "gene_name": "Zfp971", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDLVTYDDVHVNFTQEEWALLDASQKSLYKGVMVETYRNLTAIGYSWEEHTIEDHFQTSRSHGRHERSSSAEQHSEFIQCGKAFAYQSHSQRHERIHNGEKHCECNQCGKDFGTRSILQRLKRTHTGEKPYECNHCGKAFVESCTLQIHKRKHTGEKPYECNQCGKAFAQSCHLRIHKRTHTGEKPYECKQCGKAFAVSSHLGIHKRTHTGEKPYECKQCGKAFAVSSHLGIHKRTHTGEKPYECKQCDKAFVRRGKLQIHKRTHTGEKPYECKQCGKAFAHSGTLQIHKRTHTGEKPYECYQCGKAFATSCHLRRHNRTHSGEKQYECNQCGKAFASSSDLQKHKRTHTGDKPYECKQCGKAFASSSDLQKHKRTHTGEKPYECKQCGKAFAESSTLQRHKRTHTGEKPYECKQCGKAFARSCHLQIHKRTHTGEKPYECKQCGKAFARSSHLRIHKRTHTGERPYECN", "length": 470 }, "evidence": [ { "id": "HGNC:12920", "url": "https://alliancegenome.org/gene/HGNC:12920#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3Z5Y8-1", "protein_name": "Predicted gene 15446", "gene_name": "Gm15446", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDALTYDDVYVNFTQEEWALLNPSQKSLYKDVMLETYRNLNAVGYNWEDSNIEEHCESSRRHGRHERSHTGEKPFEGIQYGEAFVHHSSLQMRKIVHTGEKRYKCNQCDKAYSRHSILQIHKRTHSGEKPYECNQCDKAYSRHSILQIHKRTHSGEKPYECNQCGKAFARHSHLKIHMVTHTGEKPYKCDQCGKAFAFHSTLQVHKRTHTGEKPYECNQCSKAFAHHCHLRVHKRIHTGEKPYKCDQCGKAFVGQNDLKRHERVHTGEKPYKCNECGKAFVCNASLRTHKTTHTGVKPYECKQCTKSFASHGQLQKHERIHTGEKPYKCDQCGKAFASHDKLQKHERIHTGEKPYKCKQCTKSFASHDKLQKHERIHTGEKPYECKQCTKSFASHNKLQKHERIHTGEKPYKCDQCSKAFVYENYLQVHKKTHTGEKHYKCNECGKAFARHSHLKVHKITHTGEKPYKCNQCGKALAYHSTLQVHQRTHTGEKPYECEQCGKAFANQSYFQVHKRIHTGEKPYKCDQCGKAFVGSSDLRKHERVHTGRETLQM", "length": 553 }, "evidence": [ { "id": "HGNC:12920", "url": "https://alliancegenome.org/gene/HGNC:12920#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "E9Q2M4-1", "protein_name": "Zinc finger protein 867", "gene_name": "Zfp867", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRDSRNSEMNSVAFDDVAINFTQEEWALLDPSQKNLYRDVMEEVFRNLTSIEKGWEDQNVEDEDKNPQTNLRHIIANSGYNLYESEESSEKPYKCTQYRSSFISLMSIQRHMITDTGSKPYKCMLCGKAFHFPSEFRIHLRTHTGEKPYECKECGKAFSHSSSFRKHERTHTGERPYVCKQCGKAFNCSGSIRKHERTHTGEKPYSCKQCGKAFNCPSYLQIHERSHTGEKPYECKQCGKTFSCSSSLRKHERTHTGEKPYECKQCGKAFSCSSSFRKHERTHTGEKPYECKQCGKAFFSLTSVRTHMIKHTGNGPFKCNVCEEVFPFSSVFRRHQSSHAGEKQPYGCKQCNKWFSSNTSLQNHRRSHTGEEPYAYKQCGKAFSCPSYIRKHERAHSGEKPYPCKQCGKCFSASSSLQTHERIHAGEKPYKREQGARAFSCSTSLRRHEQAHSGENAYEYSVGKPLLPVRIDY", "length": 473 }, "evidence": [ { "id": "HGNC:12920", "url": "https://alliancegenome.org/gene/HGNC:12920#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1LSH5-1", "protein_name": "Zinc finger protein 791", "gene_name": "Zfp867", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "RDGRNSEMDSVAFDDVAINFTQEEWALLDPSQKSLYRDVMEEVFRNLTSIEKGWEDQNIEDEDKSPETNLRHIIANSGCNLYESEEHSEKPYKFTQYRNSFISLMSIQRHMIMDTGSKPYKCMLCGKAFHFPSEFRIHLRTHTGEKPYECKQCGKAFSHSSSFRKHERTHTGERPYVCKQCGKAFNCSGSIRKHERTHTGEKPYECKQCGKAFNCPSYLQIHERSHTGEKPYECKQCGKTFSCSSSLRKHERTHTGEKPYECKQCGKAFSCSSSFRKHERTHTGERPYECKQCGKAFFSLTSVRTHMIKHTGNGPFKCSVCEEVFPFSSVFRRHQTSHAGEKLYECKQCNKWFSSSTSLHNHERSHNGEKPYTCKPRGKAFIRKHERAHAGGKSYPCKQCGEWFSASSSLQMHGRIQTGEKPHKCEQGARALSCSTCMRKHEQTQSGGKAYDYGVEKPLLPVRIDY", "length": 466 }, "evidence": [ { "id": "HGNC:12920", "url": "https://alliancegenome.org/gene/HGNC:12920#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "L7N248-1", "protein_name": "Predicted gene 6871", "gene_name": "Gm6871", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRNLTNVTCVGRGFTRSSSLHVHHSSIQVRNLSDEIGVGRASARAQTYTSTGAPTQERSHTSATNVGKVSARVWTFETTSGYTPGESPTTVASVGESTRERSCMNAAGDALTFDDVHVHFTREEWSLLDPSQKRLYKDVMLDTYRNLTTIGYNWEDHNIEEQCQSGRRHGRHQTSHAGEKHCEYTQYDNVFTYHSHLHKHEQIQTQEKPSEGFQHIEALACHSSLQIHKRTDTGKKPYKCNQCDKVFSQQRHLRTHERTHTGKKPYECDQCGKAFAYQSALVLHKRTHTGEKPYECDQCGKAFAHHFTVVLHKRTHTGEKPYECDQCGKAFAYQSALVLHKRTHTGEKPYECNQCGKTFAQINHLRTHKVVHTGEKPYKCNQCDKAFSQQSHLRIHERTHTGEKPYKCNQCGKSFVSHSHLQSHGRIHTGEKPYKCNQCDKAFAQHNSLQIHKRTHTGEKPYKCNQCDKAFAQSSSLQYHKRTHTGEKPYECDQCGKAFTHPSTVVLHKRTHTGEKPYECDQCGKAFAHHSTLQYHKKNHTEETL", "length": 545 }, "evidence": [ { "id": "HGNC:12920", "url": "https://alliancegenome.org/gene/HGNC:12920#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P52737-1", "protein_name": "Zinc finger protein 136", "gene_name": "ZNF136", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDSVAFEDVDVNFTQEEWALLDPSQKNLYRDVMWETMRNLASIGKKWKDQNIKDHYKHRGRNLRSHMLERLYQTKDGSQRGGIFSQFANQNLSKKIPGVKLCESIVYGEVSMGQSSLNRHIKDHSGHEPKEYQEYGEKPDTRNQCWKPFSSHHSFRTHEIIHTGEKLYDCKECGKTFFSLKRIRRHIITHSGYTPYKCKVCGKAFDYPSRFRTHERSHTGEKPYECQECGKAFTCITSVRRHMIKHTGDGPYKCKVCGKPFHSLSSFQVHERIHTGEKPFKCKQCGKAFSCSPTLRIHERTHTGEKPYECKQCGKAFSYLPSLRLHERIHTGEKPFVCKQCGKAFRSASTFQIHERTHTGEKPYECKECGEAFSCIPSMRRHMIKHTGEGPYKCKVCGKPFHSLSPFRIHERTHTGEKPYVCKHCGKAFVSSTSIRIHERTHTGEKPYECKQCGKAFSYLNSFRTHEMIHTGEKPFECKRCGKAFRSSSSFRLHERTHTGQKPYHCKECGKAYSCRASFQRHMLTHAEDGPPYKCMWESL", "length": 540 }, "evidence": [ { "id": "HGNC:12920", "url": "https://alliancegenome.org/gene/HGNC:12920#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-89", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-89#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "F1QC22", "url": "https://www.uniprot.org/uniprotkb/F1QC22" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "F1QC22", "url": "https://www.uniprot.org/uniprotkb/F1QC22" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "F1QC22", "url": "https://www.uniprot.org/uniprotkb/F1QC22" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "F1QC22", "url": "https://www.uniprot.org/uniprotkb/F1QC22" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 267, "end_pos": 269, "annotation": "n_glycosylation_sequon" }, { "start_pos": 421, "end_pos": 423, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "F1QC22", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/F1QC22" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 62, "end_pos": 89, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 267, "end_pos": 269 }, { "start_pos": 421, "end_pos": 423 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7FED5-1", "uniprot_ac": "E7FED5", "uniprot_id": "E7FED5_DANRE", "mass": { "chemical_mass": 62844.0, "monoisotopic_mass": 62844.0 }, "refseq": { "ac": "XP_005169190", "name": "kelch-like protein 23 isoform X2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169190" }, "gene_names": [ { "name": "klhl23", "type": "recommended", "evidence": [ { "id": "E7FED5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FED5" } ] }, { "name": "klhl23", "type": "synonym", "evidence": [ { "id": "XP_005169190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169190" } ] } ], "protein_names": [ { "name": "Kelch-like protein 23 isoform X2", "type": "synonym", "evidence": [ { "id": "E7FED5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FED5/entry#names_and_taxonomy" } ] }, { "name": "kelch-like protein 23 isoform X2", "type": "synonym", "evidence": [ { "id": "XP_005169190", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169190" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005169190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169190" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7FED5", "url": "https://www.uniprot.org/uniprotkb/E7FED5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "klhl23", "url": "https://www.uniprot.org/uniprotkb/E7FED5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-458", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-458", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000078475", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000078475", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "559613", "url": "https://www.ncbi.nlm.nih.gov/gene/559613", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000210", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000210", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006652", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006652", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011705", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011705", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017096", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017096", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "HIWDPIS", "url": "https://omabrowser.org/oma/group/HIWDPIS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0A8N7UUT7", "url": "https://www.orthodb.org/?gene=A0A8N7UUT7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E7FED5", "url": "https://www.orthodb.org/?gene=E7FED5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24412:SF304", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24412:SF304", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00651", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00651", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01344", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01344", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF24681", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF24681", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005169190", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005169190", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0A8N7UUT7", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUT7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0A8N7UUT7-1", "url": "https://www.uniprot.org/uniprotkb/A0A8N7UUT7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FED5", "url": "https://www.uniprot.org/uniprotkb/E7FED5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7FED5-1", "url": "https://www.uniprot.org/uniprotkb/E7FED5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-458", "url": "https://zfin.org/ZDB-GENE-081104-458", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSGNAQSGYSYDFYDASHPSEVLEALHEFHNSGLFTDIALQSSSGQLFHCHKAVLSARSSYFKVMFTLDMRERANDTINLPCVDGEILGALVTYVYTAKIGITQNNVQRLLEAADLLQFNSLKKACENFLIRLLDVDNCLGMHSFAELHVCSALERAALRIILSRFEDVTLQDEFPETGFQKLMAILSTENLNVWKDTTLLDAVVKWVVYDVASRIDHIQELLNCIHINVDDVYLKMALDLRKCCSESKLRSLILTSLKPSKGFSDCCKKPTCSLYVIGGYYWHPLCEVHMWDPVSNTWVQGKDMPDFARESYSVVLLGADIYVTGGYRTETVDALDNVWIYNTDSDEWTEGCPMITARYYHCSVALRGCVYVIGGYTAGAPTQETEFYDPLKKTWFPVAEMIQGVGNATACVVNDRVYVTGGHYGYRGTCTYEKIQTYRPDINEWSITTICPHPEYGLCSVSLYNKLYLVGGQTTITDCYDPERDEWRQMCAMKERRMECGSAVINGCIYVAGGYSYSKGTYLQSIERYDPEIDCWEIVGNLPSAARSHGCVCVFGV", "length": 558, "header": "tr|E7FED5-1|E7FED5_DANRE Isoform 1 of Kelch-like protein 23 isoform X2 OS=Danio rerio OX=7955 GN=klhl23 PE=4 SV=1 CANONICAL=E7FED5-1" }, "isoforms": [ { "isoform_ac": "A0A8N7UUT7-1", "url": "https://www.uniprot.org/uniprotkb/E7FED5/entry#A0A8N7UUT7-1", "sequence": { "sequence": "MSDLAKHKALCWGYNLFVAMSGNAQSGYSYDFYDASHPSEVLEALHEFHNSGLFTDIALQSSSGQLFHCHKAVLSARSSYFKVMFTLDMRERANDTINLPCVDGEILGALVTYVYTAKIGITQNNVQRLLEAADLLQFNSLKKACENFLIRLLDVDNCLGMHSFAELHVCSALERAALRIILSRFEDVTLQDEFPETGFQKLMAILSTENLNVWKDTTLLDAVVKWVVYDVASRIDHIQELLNCIHINVDDVYLKMALDLRKCCSESKLRSLILTSLKPSKGFSDCCKKPTCSLYVIGGYYWHPLCEVHMWDPVSNTWVQGKDMPDFARESYSVVLLGADIYVTGGYRTETVDALDNVWIYNTDSDEWTEGCPMITARYYHCSVALRGCVYVIGGYTAGAPTQETEFYDPLKKTWFPVAEMIQGVGNATACVVNDRVYVTGGHYGYRGTCTYEKIQTYRPDINEWSITTICPHPEYGLCSVSLYNKLYLVGGQTTITDCYDPERDEWRQMCAMKERRMECGSAVINGCIYVAGGYSYSKGTYLQSIERYDPEIDCWEIVGNLPSAARSHGCVCVFGV", "length": 577, "header": "tr|A0A8N7UUT7-1|E7FED5_DANRE Computationally mapped isoform of Kelch-like protein 23 isoform X2 OS=Danio rerio OX=7955 GN=klhl23 PE=4 SV=1 CANONICAL=E7FED5-1" }, "locus": {} }, { "isoform_ac": "E7FED5-1", "url": "https://www.uniprot.org/uniprotkb/E7FED5/entry#E7FED5-1", "sequence": { "sequence": "MSGNAQSGYSYDFYDASHPSEVLEALHEFHNSGLFTDIALQSSSGQLFHCHKAVLSARSSYFKVMFTLDMRERANDTINLPCVDGEILGALVTYVYTAKIGITQNNVQRLLEAADLLQFNSLKKACENFLIRLLDVDNCLGMHSFAELHVCSALERAALRIILSRFEDVTLQDEFPETGFQKLMAILSTENLNVWKDTTLLDAVVKWVVYDVASRIDHIQELLNCIHINVDDVYLKMALDLRKCCSESKLRSLILTSLKPSKGFSDCCKKPTCSLYVIGGYYWHPLCEVHMWDPVSNTWVQGKDMPDFARESYSVVLLGADIYVTGGYRTETVDALDNVWIYNTDSDEWTEGCPMITARYYHCSVALRGCVYVIGGYTAGAPTQETEFYDPLKKTWFPVAEMIQGVGNATACVVNDRVYVTGGHYGYRGTCTYEKIQTYRPDINEWSITTICPHPEYGLCSVSLYNKLYLVGGQTTITDCYDPERDEWRQMCAMKERRMECGSAVINGCIYVAGGYSYSKGTYLQSIERYDPEIDCWEIVGNLPSAARSHGCVCVFGV", "length": 558, "header": "tr|E7FED5-1|E7FED5_DANRE Isoform 1 of Kelch-like protein 23 isoform X2 OS=Danio rerio OX=7955 GN=klhl23 PE=4 SV=1 CANONICAL=E7FED5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JW57-1", "protein_name": "Kelch-like family member 23", "gene_name": "Klhl23", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVRCGPAMALKGQEDYIYLFKDSSHPVDFLDAFRTFYMDGLFTDITLQCPSGIIFHCHRAVLAACSNYFKAMFTADMKEKFKSKIKLSGIHHDILEGLVNYAYTSQIEITKRNVQSLLEAADLLQFLSVKKACEQFLVRHLDIDNCIGMHSFAEFHVCSELEKESRRILCSRFKEVWQQEEFLEISLEKFLFILSRKNLSVWKEEAILEPVIKWTAHDVENRVECLYNLLSYVNIDIDPVYLKTALGLQRSCLLTENKIRSLIYNALNPMHKEISQRSTATMYIIGGYYWHPLSEVHIWDPLTNVWIQGAEIPDYTRESYGVTCLGPNIYVTGGYRTDNIDALDTVWIYNSEGDEWTEGLPMLNARYYHCAVTLGGCVYALGGYRKGAPAEEAEFYDPLKEKWLPIANMIKGVGNATACVLHEVIYVIGGHCGYRGSCTYDKVQSYNSDINEWSLITASPHPEYGLCSVPFENKLYLVGGQTTITECYDPEQNEWRETAPMMERRMECGAVIMNGCIYVTGGYSYSKGTYLQSIEKYDPDLNKWEIVGNLPSAMRSHGCVCVYNV", "length": 566 }, "evidence": [ { "id": "HGNC:27506", "url": "https://alliancegenome.org/gene/HGNC:27506#orthology", "database": "AGR" }, { "id": "RGD:1307166", "url": "https://alliancegenome.org/gene/RGD:1307166#orthology", "database": "AGR" }, { "id": "MGI:2683536", "url": "https://alliancegenome.org/gene/MGI:2683536#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-458", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-458#orthology", "database": "AGR" }, { "id": "E7FED5", "url": "https://omabrowser.org/oma/group/E7FED5/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A286ZIG7-1", "protein_name": "Kelch like family member 23", "gene_name": "KLHL23", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALKGQEDYIYLFKDSAHPVDFLDAFRTFYLDGLFTDITLQCPSGIIFHCHRAVLAACSNYFKAMFTADMKEKFKNKIKISGIHHDILEGLVNYAYTSQIEITKRNVQSLLEAADLLQFLSVKKACEQFLVRHLDIDNCIGMHSFAEFHMCTELEKESRRILCSRFKEVWQQEEFLEISLEKFLFILSRKNLSVWKDEAIIEPVIKWTAHDVENRIECLYNLLSYVNIDIDPVYLKTALGLHRSCLLTENKIRSLIYNALNPMHKEISQRSTATMYIIGGYYWHPLSEVHIWDPLTNVWIQGAEIPDYTRESYGVTCLGPNIYVTGGYRTDNIEALDTVWIYNSESDEWTEGLPMLNARYYHCAVTLGGCVYALGGYRKGAPAEEAEFYDPLKEKWIPIANMIKGVGNATACVLHEVIYVIGGHCGYRGSCTYDKVQSYNSDINEWSLITSSPHPEYGLCSVPFENKLYLVGGQTTITECYDPEQNEWREIAPMMERRMECGAVIMNGCIYVTGGYSYSKGTYLQSIEKYDPDLNKWEIVGNLPSAMRSHGCVCVYNV", "length": 558 }, "evidence": [ { "id": "E7FED5", "url": "https://omabrowser.org/oma/group/E7FED5/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZNI2-1", "protein_name": "Kelch like family member 23", "gene_name": "KLHL23", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALPGQEDYEFAYRDSSHPVCLLDAFRAFYLDGLFTDIALQAASGVLLHCHRAVLAACSSYFRAMFTADMKEKSKNQIRLPELSHAVLEALVNYAYTSQIQITKRNVQSLLQAADLLQFVSVKRACEQFLIRHLDADNCLGMHAFAEHHNCLELEKESRRMLLWQFEEVWKQEEFLDVSKEKLAFILSRENLNVWKEEAAVGAVVRWVAHNVEERIEDIYELLSCIKLDLDNVYLRSALSLQKKCRLNDNKIRSLVYSALNPSPKGLSKRPTATMCVVGGYYWHPLSEVHVWDPLTNAWLQGAEMPDHTRESYGVTSLGPDIYVTGGYRTESIEALDTVWIYNSERDEWAEGCPMLDARYYHCAVSLSGCVYALGGYRKGAPVQEAEFYDPLKKKWVPIANMIKGVGNATACVLHEVIFVTGGHYGYRGSCTYDKIQRYHSGSNEWSIVTTSPHPEYGLCSITLQNKIYFVGGQTTITDCYDPEQDEWKQMAHMLERRMECGAVVMNGCIYVTGGYSYSKGTYLQSIEKYNPELNTWEAVGNLPSAMRSHGCVCVYNV", "length": 558 }, "evidence": [ { "id": "E7FED5", "url": "https://omabrowser.org/oma/group/E7FED5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3GU91-1", "protein_name": "Kelch-like protein 23", "gene_name": "Klhl23", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MALKGQEDYIYLFKDSSHPVDFLDAFRTFYLDGLFTDITLQCPSGIIFHCHRVVLAACSNYFKAMFTADMKEKFKSKIKLFGIHHDILEGLVNYAYTSQIEITKRNVQSLLEAADLLQFLSVKKACEQFLVRHLDIDNCIGMHSFAEFHVCSELEKESRRILCSRFKEVWQQEEFLEISLEKFLFILSRKNLNVWKEDAVIEPVIKWTAHDVENRIECLCNLLSYINIDIDPVYLKTALGLQRSCLLTENKIRSLIYNALNPMHKEISQRSTATMYIIGGYYWHPLSEVHIWDPLTNVWIQGAEIPDYTRESYGVTCLGPNIYVTGGYRTDNIDALDTVWIYNSEGDEWSEGLPMLNARYYHCAVTLGGCVYALGGYRKGAPAEEAEFYDPLKEKWLPIANMIKGVGNATACVLHEVIYVIGGHCGYRGSCTYDKVQSYNSDINEWSLITASPHPEYGLCSVPFENKLYLVGGQTTITECYDPEQNEWRETAPTMERRMECGAVIMNGCIYVTGGYSYSKGTYLQSIERYDPDLNKWEIVGNLPSAMRSHGCVCVYNV", "length": 558 }, "evidence": [ { "id": "E7FED5", "url": "https://omabrowser.org/oma/group/E7FED5/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6GQU2-1", "protein_name": "Kelch-like protein 23", "gene_name": "Klhl23", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALKGQEDYIFHFKDSSHPVDFLDAFRTFYMDGLFTDITLQCPSGIIFHCHRAVLAACSNYFKAMFTADMKEKFKSKIKLSGIHHDILEGLVNYAYTSQIEITKRNVQSLLEAADLLQFLSVKKACEQFLVRHLDIDNCIGMHSFAEFHVCSELEKESRRILCSRFKEVWQQEEFLEISLEKFLFILSRKNLSVWKEEAILEPVIKWTAHDVENRIECIYNLLSYINIDIDPVYLKTALGLQRSCLLTENKIRSLIYNALNPMHKEISQRSTATMYIIGGYYWHPLSEVHIWDPLTNVWIQGAEIPDYTRESYGVTCLGPNIYVTGGYRTDNIDALDTVWIYNSEGDEWTEGLPMLNARYYHCAVTLGGCVYALGGYRKGAPAEEAEFYDPLKEKWLPIANMIKGVGNATACVLHEVIYVIGGHCGYRGSCTYDKVQSYNSDINEWSLITASPHPEYGLCSVPFENKLYLVGGQTTITECYDPEQNEWRETAPMMERRMECGAVIMNGCIYVTGGYSYSKGTYLQSIEKYDPDLNKWEIVGNLPSAMRSHGCVCVYNV", "length": 558 }, "evidence": [ { "id": "HGNC:27506", "url": "https://alliancegenome.org/gene/HGNC:27506#orthology", "database": "AGR" }, { "id": "RGD:1307166", "url": "https://alliancegenome.org/gene/RGD:1307166#orthology", "database": "AGR" }, { "id": "MGI:2683536", "url": "https://alliancegenome.org/gene/MGI:2683536#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-458", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-458#orthology", "database": "AGR" }, { "id": "E7FED5", "url": "https://omabrowser.org/oma/group/E7FED5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NBE8-1", "protein_name": "Kelch-like protein 23", "gene_name": "KLHL23", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALKGQEDYIYLFKDSTHPVDFLDAFRTFYLDGLFTDITLQCPSGIIFHCHRAVLAACSNYFKAMFTADMKEKFKNKIKLSGIHHDILEGLVNYAYTSQIEITKRNVQSLLEAADLLQFLSVKKACERFLVRHLDIDNCIGMHSFAEFHVCPELEKESRRILCSKFKEVWQQEEFLEISLEKFLFILSRKNLSVWKEEAIIEPVIKWTAHDVENRIECLYNLLSYINIDIDPVYLKTALGLQRSCLLTENKIRSLIYNALNPMHKEISQRSTATMYIIGGYYWHPLSEVHIWDPLTNVWIQGAEIPDYTRESYGVTCLGPNIYVTGGYRTDNIEALDTVWIYNSESDEWTEGLPMLNARYYHCAVTLGGCVYALGGYRKGAPAEEAEFYDPLKEKWIPIANMIKGVGNATACVLHDVIYVIGGHCGYRGSCTYDKVQSYNSDINEWSLITSSPHPEYGLCSVPFENKLYLVGGQTTITECYDPEQNEWREIAPMMERRMECGAVIMNGCIYVTGGYSYSKGTYLQSIEKYDPDLNKWEIVGNLPSAMRSHGCVCVYNV", "length": 558 }, "evidence": [ { "id": "HGNC:27506", "url": "https://alliancegenome.org/gene/HGNC:27506#orthology", "database": "AGR" }, { "id": "RGD:1307166", "url": "https://alliancegenome.org/gene/RGD:1307166#orthology", "database": "AGR" }, { "id": "MGI:2683536", "url": "https://alliancegenome.org/gene/MGI:2683536#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-458", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-458#orthology", "database": "AGR" }, { "id": "E7FED5", "url": "https://omabrowser.org/oma/group/E7FED5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7FED5", "url": "https://www.uniprot.org/uniprotkb/E7FED5" } ], "pmid": "" }, { "name": "Cul3-RING ubiquitin ligase complex", "id": "GO:0031463", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031463", "evidence": [ { "database": "UniProtKB", "id": "E7FED5", "url": "https://www.uniprot.org/uniprotkb/E7FED5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteasome-mediated ubiquitin-dependent protein catabolic process", "id": "GO:0043161", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043161", "evidence": [ { "database": "UniProtKB", "id": "E7FED5", "url": "https://www.uniprot.org/uniprotkb/E7FED5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "ubiquitin-like ligase-substrate adaptor activity", "id": "GO:1990756", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990756", "evidence": [ { "database": "UniProtKB", "id": "E7FED5", "url": "https://www.uniprot.org/uniprotkb/E7FED5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7FED5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7FED5" }, { "id": "PS50097", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50097" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BTB", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 104, "start_aa": "Thr", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 408, "end_pos": 410 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0S6P0-1", "uniprot_ac": "B0S6P0", "uniprot_id": "B0S6P0_DANRE", "mass": { "chemical_mass": 21171.0, "monoisotopic_mass": 21171.0 }, "refseq": { "ac": "NP_001116790", "name": "crystallin, gamma M2d9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116790" }, "gene_names": [ { "name": "crygm2d9", "type": "recommended", "evidence": [ { "id": "B0S6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6P0" } ] }, { "name": "crygm2d9", "type": "synonym", "evidence": [ { "id": "NP_001116790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116790" } ] }, { "name": "si:ch211-212n6.12", "type": "synonym", "evidence": [ { "id": "NP_001116790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116790" }, { "id": "B0S6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6P0" } ] } ], "protein_names": [ { "name": "Crystallin, gamma M2d9", "type": "synonym", "evidence": [ { "id": "B0S6P0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6P0/entry#names_and_taxonomy" } ] }, { "name": "crystallin, gamma M2d9", "type": "synonym", "evidence": [ { "id": "NP_001116790", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116790" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH997319.1, CN512549.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000009.1. 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The reference sequence was derived from JBMGRA010000009.1 and EH450534.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001188329", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188329" } ] } ], "disease": [ { "disease_id": "DOID:0051065", "recommended_name": { "id": "DOID:0051065", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0051065", "name": "chronic pancreatitis", "description": "A pancreatitis that is characterized by long-term inflamation of the pancreas." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0051065", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0051065" } ] }, { "disease_id": "DOID:10652", "recommended_name": { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer's disease", "description": "A tauopathy that is characterized by memory lapses, confusion, emotional instability and progressive loss of mental ability and results in progressive memory loss, impaired thinking, disorientation, and changes in personality and mood starting and leads in advanced cases to a profound decline in cognitive and physical functioning and is marked histologically by the degeneration of brain neurons especially in the cerebral cortex and by the presence of neurofibrillary tangles and plaques containing beta-amyloid." }, "synonyms": [ { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimer disease", "description": "" }, { "id": "DOID:10652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10652", "name": "Alzheimers dementia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "10652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10652" } ] }, { "disease_id": "DOID:11446", "recommended_name": { "id": "DOID:11446", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:11446", "name": "sciatic neuropathy", "description": "" }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "11446", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:11446" } ] }, { "disease_id": "DOID:12894", "recommended_name": { "id": "DOID:12894", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12894", "name": "Sjogren's syndrome", "description": "An autoimmune disease that involves attack of immune cells which destroy the exocrine glands that produce tears and saliva." }, "synonyms": [ { "id": "DOID:12894", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12894", "name": "Sicca syndrome", "description": "" }, { "id": "DOID:12894", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12894", "name": "Sjogren syndrome", "description": "" }, { "id": "DOID:12894", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:12894", "name": "xerodermosteosis", "description": "" }, { "id": "MONDO:0010030", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010030", "name": "Sjogren syndrome", "description": "An autoimmune disorder in which immune cells attack and destroy the glands that produce tears and saliva. Sjgren syndrome is also associated with rheumatic disorders such as rheumatoid arthritis or systemic lupus erythematosus. The hallmark symptoms of Sjgren syndrome are dry mouth and dry eyes. In addition, Sjogren syndrome may cause skin, nose, and vaginal dryness. It also may affect other organs of the body including the kidneys, blood vessels, lungs, liver, pancreas, and brain" }, { "id": "MONDO:0010030", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010030", "name": "Sjogren syndrome", "description": "" }, { "id": "MONDO:0010030", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010030", "name": "Sjgren syndrome", "description": "" }, { "id": "MONDO:0010030", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010030", "name": "Sjgren-Gougerot syndrome", "description": "" }, { "id": "MONDO:0010030", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010030", "name": "primary Sjogren-Gougerot syndrome", "description": "" }, { "id": "MONDO:0010030", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010030", "name": "primary Sjgren-Gougerot syndrome", "description": "" }, { "id": "MONDO:0010030", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010030", "name": "sicca syndrome", "description": "" }, { "id": "MONDO:0010030", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0010030", "name": "syndrome, Sjogren's", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "12894", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:12894" } ] }, { "disease_id": "DOID:219", "recommended_name": { "id": "DOID:219", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:219", "name": "colon cancer", "description": "A colorectal cancer that is located_in the colon." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "219", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:219" } ] }, { "disease_id": "DOID:2913", "recommended_name": { "id": "DOID:2913", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:2913", "name": "acute pancreatitis", "description": "A pancreatitis that is characterized by inflammation of the pancreas over a short period of time and has symptoms of severe abdominal pain, nausea, vomiting, diarrhea, fever, and shock." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "2913", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:2913" } ] }, { "disease_id": "DOID:4947", "recommended_name": { "id": "DOID:4947", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4947", "name": "cholangiocarcinoma", "description": "A bile duct adenocarcinoma that has_material_basis_in bile duct epithelial cells." }, "synonyms": [ { "id": "DOID:4947", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4947", "name": "adult primary Cholangiocarcinoma", "description": "" }, { "id": "DOID:4947", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4947", "name": "adult primary cholangiocellular carcinoma", "description": "" }, { "id": "DOID:4947", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4947", "name": "cholangiosarcoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "4947", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4947" } ] }, { "disease_id": "DOID:5082", "recommended_name": { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "liver cirrhosis", "description": "" }, "synonyms": [ { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "Cirrhosis", "description": "" }, { "id": "DOID:5082", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5082", "name": "cirrhosis of liver", "description": "" }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis of liver", "description": "A disorder characterized by replacement of the liver parenchyma with fibrous tissue and regenerative nodules. It is usually caused by alcoholism, hepatitis B, and hepatitis C. Complications include the development of ascites, esophageal varices, bleeding, and hepatic encephalopathy." }, { "id": "MONDO:0005155", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005155", "name": "cirrhosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5082", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5082" } ] }, { "disease_id": "DOID:552", "recommended_name": { "id": "DOID:552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:552", "name": "pneumonia", "description": "A lung disease that involves lung parenchyma or alveolar inflammation and abnormal alveolar filling with fluid (consolidation and exudation). It results from a variety of causes including infection with bacteria, viruses, fungi or parasites, and chemical or physical injury to the lungs. It is accompanied by fever, chills, cough, and difficulty in breathing." }, "synonyms": [ { "id": "DOID:552", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:552", "name": "acute pneumonia", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "552", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:552" } ] }, { "disease_id": "DOID:5844", "recommended_name": { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "myocardial infarction", "description": "A coronary artery disease characterized by myocardial cell death (myocardial necrosis) due to prolonged ischaemia." }, "synonyms": [ { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "Myocardial infarct", "description": "" }, { "id": "DOID:5844", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:5844", "name": "heart attack", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, 2", "description": "" }, { "id": "MONDO:0012058", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0012058", "name": "myocardial infarction, susceptibility to, type 2", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "5844", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:5844" } ] }, { "disease_id": "DOID:684", "recommended_name": { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "hepatocellular carcinoma", "description": "A liver carcinoma that has_material_basis_in undifferentiated hepatocytes and located_in the liver." }, "synonyms": [ { "id": "DOID:684", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:684", "name": "Hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "A malignant tumor that arises from hepatocytes. Hepatocellular carcinoma is relatively rare in the United States but very common in all African countries south of the Sahara and in Southeast Asia. Most cases are seen in patients over the age of 50 years, but this tumor can also occur in younger individuals and even in children. Hepatocellular carcinoma is more common in males than females and is associated with hepatitis B, hepatitis C, chronic alcohol abuse and cirrhosis. Serum elevation of alpha-fetoprotein occurs in a large percentage of patients with hepatocellular carcinoma. Grossly, hepatocellular carcinoma may present as a single mass, as multiple nodules, or as diffuse liver involvement. Microscopically, there is a wide range of differentiation from tumor to tumor (well differentiated to poorly differentiated tumors). Hepatocellular carcinomas quickly metastasize to regional lymph nodes and lung. The overall median survival of untreated liver cell carcinoma is about 4 months. The most effective treatment of hepatocellular carcinoma is complete resection of the tumor. Lately, an increasing number of tumors have been treated with liver transplantation." }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "HCC", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "cancer, hepatocellular", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "carcinoma, hepatocellular, malignant", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoblastoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular adenocarcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular cancer, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, childhood type, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatocellular carcinoma, somatic", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell cancer (hepatocellular carcinoma)", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "liver cell carcinoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "primary carcinoma of the liver cells", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult hepatoma", "description": "" }, { "id": "MONDO:0007256", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0007256", "name": "adult primary hepatocellular carcinoma", "description": "" }, { "id": "MIM:114550", "resource": "MIM", "url": "https://www.omim.org/entry/114550", "name": "Hepatocellular carcinoma", "description": "Hepatocellular carcinoma" } ], "unlinked_id_list": [], "evidence": [ { "id": "684", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:684" } ] }, { "disease_id": "DOID:9352", "recommended_name": { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes mellitus", "description": "A diabetes mellitus that is characterized by high blood sugar, insulin resistance, and relative lack of insulin." }, "synonyms": [ { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "NIDDM", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "non-insulin-dependent diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type 2 diabetes", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "type II diabetes mellitus", "description": "" }, { "id": "DOID:9352", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9352", "name": "insulin resistance", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "type 2 diabetes mellitus", "description": "A type of diabetes mellitus that is characterized by insulin resistance or desensitization and increased blood glucose levels. This is a chronic disease that can develop gradually over the life of a patient and can be linked to both environmental factors and heredity." }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "NIDDM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2D", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "T2DM - type 2 diabetes mellitus", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "adult-onset diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitis type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, association with", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, noninsulin-dependent, late onset", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes mellitus, type II", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "diabetes, type 2", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "insulin resistance, severe, digenic", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent diabetes", "description": "" }, { "id": "MONDO:0005148", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0005148", "name": "non-insulin dependent 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"B0S6P2", "url": "https://www.uniprot.org/uniprotkb/B0S6P2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S6P2-1", "url": "https://www.uniprot.org/uniprotkb/B0S6P2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-438", "url": "https://zfin.org/ZDB-GENE-070912-438", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMVMLRSLLLLSLFSMGNAAARRCTRQWSRFGSRCFRYFSVPVNWVTAERNCQLLGGNLVSVQNGMENDFLLSLIPNSERFFIGGYDGEDEENWFWSEGSSFGYTNWCSGEPNNMNTEHCLEINWTSDRCWNNLPCSTEQGYICAKNLDGCS", "length": 152, "header": "tr|B0S6P2-1|B0S6P2_DANRE Isoform 1 of Lectin precursor OS=Danio rerio OX=7955 GN=lectin PE=4 SV=1 CANONICAL=B0S6P2-1" }, "isoforms": [ { "isoform_ac": "B0S6P2-1", "url": "https://www.uniprot.org/uniprotkb/B0S6P2/entry#B0S6P2-1", "sequence": { "sequence": 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} ] }, { "title": "Pathogen invasion changes the intestinal microbiota composition and induces innate immune responses in the zebrafish intestine.", "journal": "Fish Shellfish Immunol.", "date": "2017", "authors": "Yang Hui-Ting, Zou Song-Song, Zhai Li-Juan, Wang Yao, Zhang Fu-Miao, An Li-Guo, Yang Gui-Wen", "evidence": [ { "database": "UniProtKB", "id": "B0S6P2", "url": "https://www.uniprot.org/uniprotkb/B0S6P2" } ], "reference": [ { "type": "PubMed", "id": "28964859", "url": "https://glygen.org/publication/PubMed/28964859" } ] } ], "pathway": [ { "id": "dre:560034", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560034", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A140LFS0-1", "protein_name": "Uncharacterized protein LOC569235 precursor", "gene_name": "si:dkey-241l7.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": 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"database": "AGR" }, { "id": "HGNC:8601", "url": "https://alliancegenome.org/gene/HGNC:8601#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M1RF65-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "si:ch211-125e6.14", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MYCIGQDEKCPCGWKNSGSRCFKFFSESVDWITAEINCQSLGTNLASIQNKVENDFLLSLVPDSTRCWIGGHDGEQEGQWLWTDGSVYNYTNWCPGEPNNNNGKENCLEINWTSNRCWNDQRCSTSMGCLCGKKL", "length": 135 }, "evidence": [ { "id": "RGD:3256", "url": "https://alliancegenome.org/gene/RGD:3256#orthology", "database": "AGR" }, { "id": "RGD:621401", "url": "https://alliancegenome.org/gene/RGD:621401#orthology", "database": "AGR" }, { "id": "RGD:3552", "url": "https://alliancegenome.org/gene/RGD:3552#orthology", "database": "AGR" }, { "id": "RGD:3254", "url": "https://alliancegenome.org/gene/RGD:3254#orthology", "database": "AGR" }, { "id": "MGI:1914959", "url": "https://alliancegenome.org/gene/MGI:1914959#orthology", "database": "AGR" }, { "id": "HGNC:22977", "url": "https://alliancegenome.org/gene/HGNC:22977#orthology", "database": "AGR" }, { "id": "HGNC:9952", "url": "https://alliancegenome.org/gene/HGNC:9952#orthology", "database": "AGR" }, { "id": "HGNC:9951", "url": "https://alliancegenome.org/gene/HGNC:9951#orthology", "database": "AGR" }, { "id": "HGNC:8601", "url": "https://alliancegenome.org/gene/HGNC:8601#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M9PGK7-1", "protein_name": "Immune-related, lectin-like receptor 3 isoform X1", "gene_name": "illr3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSVYENSVFAFSTGNSDENDSQYKGHFSNYRESKREVNTAKWTKVLLIVFAVSLVFALGGLCAVRIQYVSVSAQLSAQETNGTIMSRQLDKLTANFTTVRDHLHINELLMKELTANYSRVKEQLSISEETVRKLSRFNQSSGCAICAIHWTHSGEKCYYFSTVKMNWTQSRDHCVTKGGHLVIITSQAEQEFLTSNVKETHWIGLNDLDTEGRWLWVDNQPLSQTEEFWMKRENGVSEPDNWTKQHVDGEDCASLGHPDGETDFWTDAYCFEEKRFVCEAAAAV", "length": 285 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32T8Q9-1", "protein_name": "Ladderlectin isoform X1", "gene_name": "si:dkey-241l7.3", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFRFMMFLLRSLLLLSIVFSMEGADEERLRCERGWSGSGSRCFRFFSRSVNWVTAERNCQSLGGNLASVHDQVENDFLLTLVPGSTRCWIGGHDGEQDGQWLWSDGSVYGYTNWCSGEPSGGSEHCLEINWTSDRCWNDQRCSTRMGYLCAKRRVPC", "length": 157 }, "evidence": [ { "id": "RGD:3256", "url": "https://alliancegenome.org/gene/RGD:3256#orthology", "database": "AGR" }, { "id": "RGD:3254", "url": "https://alliancegenome.org/gene/RGD:3254#orthology", "database": "AGR" }, { "id": "MGI:1914959", "url": "https://alliancegenome.org/gene/MGI:1914959#orthology", "database": "AGR" }, { "id": "HGNC:22977", "url": "https://alliancegenome.org/gene/HGNC:22977#orthology", "database": "AGR" }, { "id": "HGNC:9952", "url": "https://alliancegenome.org/gene/HGNC:9952#orthology", "database": "AGR" }, { "id": "HGNC:9951", "url": "https://alliancegenome.org/gene/HGNC:9951#orthology", "database": "AGR" }, { "id": "HGNC:8601", "url": "https://alliancegenome.org/gene/HGNC:8601#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0AB32TAH2-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "si:dkey-241l7.5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFRFMMFLLRSLLLLSIVFSMEGADEERLSCERGWSRSGSRCFRFFSRSVNWVTAERNCQSLGGNLASVHDQVENDFLLSLVPGSTRCWIGGHDGEQDGQWLWSDGSVYGYTNWCSGEPSSGSEHCLEINWTSNHCWNNQGCSTRMGYLCAKRRVPC", "length": 157 }, "evidence": [ { "id": "RGD:3256", "url": "https://alliancegenome.org/gene/RGD:3256#orthology", "database": "AGR" }, { "id": "RGD:621401", "url": "https://alliancegenome.org/gene/RGD:621401#orthology", "database": "AGR" }, { "id": "RGD:3552", "url": "https://alliancegenome.org/gene/RGD:3552#orthology", "database": "AGR" }, { "id": "RGD:3254", "url": "https://alliancegenome.org/gene/RGD:3254#orthology", "database": "AGR" }, { "id": "MGI:1914959", "url": "https://alliancegenome.org/gene/MGI:1914959#orthology", "database": "AGR" }, { "id": "HGNC:22977", "url": "https://alliancegenome.org/gene/HGNC:22977#orthology", "database": "AGR" }, { "id": "HGNC:9952", "url": "https://alliancegenome.org/gene/HGNC:9952#orthology", "database": "AGR" }, { "id": "HGNC:9951", "url": "https://alliancegenome.org/gene/HGNC:9951#orthology", "database": "AGR" }, { "id": "HGNC:8601", "url": "https://alliancegenome.org/gene/HGNC:8601#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "B7Z0K3-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG14866", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPPAGQQLRLTALVYLALGIALLCNGSDGETRQKYANESLADADDPSPVWSQFLEDYVLSQGSSSSGSQRKSKDLPYMGADMGINGPLSYHSSAYKRPGNNIYITRRIGEAVELEPHLRKPVESQSPIVNPQFRPMTNQMLHQQHQQMQQQQQQQQLQQRQQPGFLQQLFGIGGSGGGGGSGTQQQQHVRPVPLQQQQVQQIAQQHPQQQHLVGGQPTTFRAVSENDLYLLGAIEKLVYRVDYLESRVRRSEQLIYYLMAGNNQKEVKDPCPANFTRISDNCYYINSQQQVNWKTANSACKGLNSHLAEFEKVSENEEIMAYLLNQPTHRGRDYWLGGLNPGLLWIWSNSAKPVNPNMNLTSIAMAQKGENSTAANLVDSSEQAAEEATGEDVLNNTVQIEGKGRCLRLSYNAGKHSYVYYGQECTSRHYYICEHEDKTLDNKIKKITRELKLFE", "length": 455 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "D3ZXM6-1", "protein_name": "C-type lectin domain family 6, member A, pseudogene 1", "gene_name": "Clec6a-ps1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MVQERHPQRKGVCWTLRLWSTAVISMLLLSTCFIASCMVTYQFTMEKPNRRLSELHTYHSSLTCCSKGTMVSEKLWGCCPNHWKSFGSSCYLISTKENFWSISEQNYIHMGAHLVVINTETEQNFITQQLNESLSYFLGLSDPQGNSKWQWIDNTPFSQNVRFWHPHEPNLPEEWCASIVYWNPSKWGWNDVFCDSKHNSICETKKIYL", "length": 209 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O09037-1", "protein_name": "Regenerating islet-derived protein 3-alpha", "gene_name": "Reg3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPHLVLNSISWMLLSCLLFVFQVQGEDFQKEVPSPRTSCPMGYKAYRSHCYALVMTPKSWFQADLVCQKRPSGHLVSILSGGEASFVSSLVNGRVDNYQDIWIGLHDPTMGQQPNGGGWEWSNSDVLNYLNWDGDPSSTVNRGHCGSLTASSGFLKWGDYYCDGTLPFVCKFKQ", "length": 175 }, "evidence": [ { "id": "RGD:621401", "url": "https://alliancegenome.org/gene/RGD:621401#orthology", "database": "AGR" }, { "id": "HGNC:8601", "url": "https://alliancegenome.org/gene/HGNC:8601#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "O09049-1", "protein_name": "Regenerating islet-derived protein 3-gamma", "gene_name": "Reg3g", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPRITITIMSWMLLSCLMLLSQVQGEVAKKDAPSSRSSCPKGSRAYGSYCYALFSVSKNWYDADMACQKRPSGHLVSVLSGAEASFLSSMIKSSGNSGQYVWIGLHDPTLGYEPNRGGWEWSNADVMNYINWETNPSSSSGNHCGTLSRASGFLKWRENYCNLELPYVCKFKA", "length": 174 }, "evidence": [ { "id": "RGD:3256", "url": "https://alliancegenome.org/gene/RGD:3256#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P05451-1", "protein_name": "Lithostathine-1-alpha", "gene_name": "REG1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQTSSYFMLISCLMFLSQSQGQEAQTELPQARISCPEGTNAYRSYCYYFNEDRETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESGTDDFNVWIGLHDPKKNRRWHWSSGSLVSYKSWGIGAPSSVNPGYCVSLTSSTGFQKWKDVPCEDKFSFVCKFKN", "length": 166 }, "evidence": [ { "id": "RGD:3552", "url": "https://alliancegenome.org/gene/RGD:3552#orthology", "database": "AGR" }, { "id": "HGNC:9951", "url": "https://alliancegenome.org/gene/HGNC:9951#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-438", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-438#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P10758-1", "protein_name": "Lithostathine", "gene_name": "Reg1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTRNKYFILLSCLMVLSPSQGQEAEEDLPSARITCPEGSNAYSSYCYYFMEDHLSWAEADLFCQNMNSGYLVSVLSQAEGNFLASLIKESGTTAANVWIGLHDPKNNRRWHWSSGSLFLYKSWDTGYPNNSNRGYCVSVTSNSGYKKWRDNSCDAQLSFVCKFKA", "length": 165 }, "evidence": [ { "id": "RGD:3552", "url": "https://alliancegenome.org/gene/RGD:3552#orthology", "database": "AGR" }, { "id": "HGNC:9952", "url": "https://alliancegenome.org/gene/HGNC:9952#orthology", "database": "AGR" }, { "id": "HGNC:9951", "url": "https://alliancegenome.org/gene/HGNC:9951#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-438", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-438#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P25031-1", "protein_name": "Regenerating islet-derived protein 3-beta", "gene_name": "Reg3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLHRLAFPVMSWMLLSCLMLLSQVQGEDSPKKIPSARISCPKGSQAYGSYCYALFQIPQTWFDAELACQKRPEGHLVSVLNVAEASFLASMVKNTGNSYQYTWIGLHDPTLGGEPNGGGWEWSNNDIMNYVNWERNPSTALDRGFCGSLSRSSGFLRWRDTTCEVKLPYVCKFTG", "length": 175 }, "evidence": [ { "id": "RGD:3254", "url": "https://alliancegenome.org/gene/RGD:3254#orthology", "database": "AGR" }, { "id": "HGNC:8601", "url": "https://alliancegenome.org/gene/HGNC:8601#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-438", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-438#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P35230-1", "protein_name": "Regenerating islet-derived protein 3-beta", "gene_name": "Reg3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLPPTACSVMSWMLLSCLMLLSQVQGEDSLKNIPSARISCPKGSQAYGSYCYALFQIPQTWFDAELACQKRPGGHLVSVLNSAEASFLSSMVKRTGNSYQYTWIGLHDPTLGAEPNGGGWEWSNNDVMNYFNWERNPSTALDRAFCGSLSRASGFLKWRDMTCEVKLPYVCKFTG", "length": 175 }, "evidence": [ { "id": "RGD:3254", "url": "https://alliancegenome.org/gene/RGD:3254#orthology", "database": "AGR" }, { "id": "HGNC:8601", "url": "https://alliancegenome.org/gene/HGNC:8601#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35231-1", "protein_name": "Regenerating islet-derived protein 3-alpha", "gene_name": "Reg3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRLSFNNVSWTLLYYLFIFQVRGEDSQKAVPSTRTSCPMGSKAYRSYCYTLVTTLKSWFQADLACQKRPSGHLVSILSGGEASFVSSLVTGRVNNNQDIWIWLHDPTMGQQPNGGGWEWSNSDVLNYLNWDGDPSSTVNRGNCGSLTATSEFLKWGDHHCDVELPFVCKFKQ", "length": 174 }, "evidence": [ { "id": "RGD:621401", "url": "https://alliancegenome.org/gene/RGD:621401#orthology", "database": "AGR" }, { "id": "HGNC:8601", "url": "https://alliancegenome.org/gene/HGNC:8601#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-438", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-438#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P42854-1", "protein_name": "Regenerating islet-derived protein 3-gamma", "gene_name": "Reg3g", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLPRVALTTMSWMLLSSLMLLSQVQGEDAKEDVPTSRISCPKGSRAYGSYCYALFSVSKSWFDADLACQKRPSGHLVSVLSGSEASFVSSLIKSSGNSGQNVWIGLHDPTLGQEPNRGGWEWSNADVMNYFNWETNPSSVSGSHCGTLTRASGFLRWRENNCISELPYVCKFKA", "length": 174 }, "evidence": [ { "id": "RGD:3256", "url": "https://alliancegenome.org/gene/RGD:3256#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-438", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-438#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P43137-1", "protein_name": "Lithostathine-1", "gene_name": "Reg1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARNAYFILLSCLIVLSPSQGQEAEEDLPSARISCPEGSNAYSSYCYYFTEDRLTWADADLFCQNMNSGYLVSVLSQAEGNFVASLIKESGTTDANVWTGLHDPKRNRRWHWSSGSLFLYKSWATGSPNSSNRGYCVSLTSNTGYKKWKDDNCDAQYSFVCKFKG", "length": 165 }, "evidence": [ { "id": "RGD:3552", "url": "https://alliancegenome.org/gene/RGD:3552#orthology", "database": "AGR" }, { "id": "HGNC:9952", "url": "https://alliancegenome.org/gene/HGNC:9952#orthology", "database": "AGR" }, { "id": "HGNC:9951", "url": "https://alliancegenome.org/gene/HGNC:9951#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P48304-1", "protein_name": "Lithostathine-1-beta", "gene_name": "REG1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQTNSFFMLISSLMFLSLSQGQESQTELPNPRISCPEGTNAYRSYCYYFNEDPETWVDADLYCQNMNSGNLVSVLTQAEGAFVASLIKESSTDDSNVWIGLHDPKKNRRWHWSSGSLVSYKSWDTGSPSSANAGYCASLTSCSGFKKWKDESCEKKFSFVCKFKN", "length": 166 }, "evidence": [ { "id": "RGD:3552", "url": "https://alliancegenome.org/gene/RGD:3552#orthology", "database": "AGR" }, { "id": "HGNC:9952", "url": "https://alliancegenome.org/gene/HGNC:9952#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-438", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-438#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q06141-1", "protein_name": "Regenerating islet-derived protein 3-alpha", "gene_name": "REG3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPPMALPSVSWMLLSCLMLLSQVQGEEPQRELPSARIRCPKGSKAYGSHCYALFLSPKSWTDADLACQKRPSGNLVSVLSGAEGSFVSSLVKSIGNSYSYVWIGLHDPTQGTEPNGEGWEWSSSDVMNYFAWERNPSTISSPGHCASLSRSTAFLRWKDYNCNVRLPYVCKFTD", "length": 175 }, "evidence": [ { "id": "RGD:621401", "url": "https://alliancegenome.org/gene/RGD:621401#orthology", "database": "AGR" }, { "id": "RGD:3254", "url": "https://alliancegenome.org/gene/RGD:3254#orthology", "database": "AGR" }, { "id": "HGNC:8601", "url": "https://alliancegenome.org/gene/HGNC:8601#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-438", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-438#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q08731-1", "protein_name": "Lithostathine-2", "gene_name": "Reg2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQNNVYLILFLCLMFLSYSQGQVAEEDFPLAEKDLPSAKINCPEGANAYGSYCYYLIEDRLTWGEADLFCQNMNAGHLVSILSQAESNFVASLVKESGTTASNVWTGLHDPKSNRRWHWSSGSLFLFKSWATGAPSTANRGYCVSLTSNTAYKKWKDENCEAQYSFVCKFRA", "length": 173 }, "evidence": [ { "id": "HGNC:9952", "url": "https://alliancegenome.org/gene/HGNC:9952#orthology", "database": "AGR" }, { "id": "HGNC:9951", "url": "https://alliancegenome.org/gene/HGNC:9951#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q59DY5-1", "protein_name": "C-type lectin 37Db", "gene_name": "lectin-37Db", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMVKLLLLFLVCWSALPLESSPLGNRYNLEIGEKQYYISLAKTNWFEASNHCRQNGGFLLNLESREELELLSPHLHPAYSYWLSINDLGERGVYVSEATGLEAPFLNWSAGEPDNSSGYDRCVELWLSTTSFQMNDLPCYSSVAFICQLN", "length": 150 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q5RG14-1", "protein_name": "Uncharacterized protein LOC567708 precursor", "gene_name": "si:dkey-241l7.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMFLLRSLLLLSIVFSMEGADESVQCPRGWSGSGSRCFRFFSRSVNWVTAERNCQSLGGNLASVHDEDENDFLLGLVPVSTRCWIGGHDGEQDGQWLWSDGSVYSYTNWCSGEPSSGSEHCLEINWTSDHCWNNQGCSTRMGYLCAKRRVLC", "length": 152 }, "evidence": [ { "id": "RGD:3256", "url": "https://alliancegenome.org/gene/RGD:3256#orthology", "database": "AGR" }, { "id": "RGD:621401", "url": "https://alliancegenome.org/gene/RGD:621401#orthology", "database": "AGR" }, { "id": "RGD:3552", "url": "https://alliancegenome.org/gene/RGD:3552#orthology", "database": "AGR" }, { "id": "RGD:3254", "url": "https://alliancegenome.org/gene/RGD:3254#orthology", "database": "AGR" }, { "id": "MGI:1914959", "url": "https://alliancegenome.org/gene/MGI:1914959#orthology", "database": "AGR" }, { "id": "HGNC:22977", "url": "https://alliancegenome.org/gene/HGNC:22977#orthology", "database": "AGR" }, { "id": "HGNC:9952", "url": "https://alliancegenome.org/gene/HGNC:9952#orthology", "database": "AGR" }, { "id": "HGNC:9951", "url": "https://alliancegenome.org/gene/HGNC:9951#orthology", "database": "AGR" }, { "id": "HGNC:8601", "url": "https://alliancegenome.org/gene/HGNC:8601#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5RG16-1", "protein_name": "Uncharacterized protein LOC100124601 precursor", "gene_name": "si:dkey-241l7.4", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MMFLLRSLLLLSIVFSMEGADEERLRCERGWSGSGSRCFRFFSRSVNWVTAERNCQSLGGNLASVHDQVENDFLLSLVPGSTRCWIGGHDGEQDGQWLWSDGSVYGYTNWCSGEPSGGSEHCLEINWTSNRCWNDQRCSTRMGYLCAKRRVPC", "length": 153 }, "evidence": [ { "id": "RGD:3256", "url": "https://alliancegenome.org/gene/RGD:3256#orthology", "database": "AGR" }, { "id": "RGD:621401", "url": "https://alliancegenome.org/gene/RGD:621401#orthology", "database": "AGR" }, { "id": "RGD:3552", "url": "https://alliancegenome.org/gene/RGD:3552#orthology", "database": "AGR" }, { "id": "RGD:3254", "url": "https://alliancegenome.org/gene/RGD:3254#orthology", "database": "AGR" }, { "id": "MGI:1914959", "url": "https://alliancegenome.org/gene/MGI:1914959#orthology", "database": "AGR" }, { "id": "HGNC:22977", "url": "https://alliancegenome.org/gene/HGNC:22977#orthology", "database": "AGR" }, { "id": "HGNC:9952", "url": "https://alliancegenome.org/gene/HGNC:9952#orthology", "database": "AGR" }, { "id": "HGNC:9951", "url": "https://alliancegenome.org/gene/HGNC:9951#orthology", "database": "AGR" }, { "id": "HGNC:8601", "url": "https://alliancegenome.org/gene/HGNC:8601#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q68AX7-1", "protein_name": "Regenerating islet-derived protein 4", "gene_name": "Reg4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MASKCVRLLLLLSWVAGPEVLSDILRPSCASGWFNYRSHCYGYFRKLRNWSHAELECQSYGNGSHLASVLNPKEASVISKYITGYQRSLPVWIGLHDPQKNASWQWIDGSTNQYRPWSPRTKSEARHCTEMNPKDKFLTWNKNGCTKRQHFLCKYRP", "length": 157 }, "evidence": [ { "id": "MGI:1914959", "url": "https://alliancegenome.org/gene/MGI:1914959#orthology", "database": "AGR" }, { "id": "HGNC:22977", "url": "https://alliancegenome.org/gene/HGNC:22977#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6EIG7-1", "protein_name": "C-type lectin domain family 6 member A", "gene_name": "CLEC6A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQEQQPQSTEKRGWLSLRLWSVAGISIALLSACFIVSCVVTYHFTYGETGKRLSELHSYHSSLTCFSEGTKVPAWGCCPASWKSFGSSCYFISSEEKVWSKSEQNCVEMGAHLVVFNTEAEQNFIVQQLNESFSYFLGLSDPQGNNNWQWIDKTPYEKNVRFWHLGEPNHSAEQCASIVFWKPTGWGWNDVICETRRNSICEMNKIYL", "length": 209 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6UW15-1", "protein_name": "Regenerating islet-derived protein 3-gamma", "gene_name": "REG3G", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLPPMALPSVSWMLLSCLILLCQVQGEETQKELPSPRISCPKGSKAYGSPCYALFLSPKSWMDADLACQKRPSGKLVSVLSGAEGSFVSSLVRSISNSYSYIWIGLHDPTQGSEPDGDGWEWSSTDVMNYFAWEKNPSTILNPGHCGSLSRSTGFLKWKDYNCDAKLPYVCKFKD", "length": 175 }, "evidence": [ { "id": "RGD:3256", "url": "https://alliancegenome.org/gene/RGD:3256#orthology", "database": "AGR" }, { "id": "RGD:621401", "url": "https://alliancegenome.org/gene/RGD:621401#orthology", "database": "AGR" }, { "id": "RGD:3254", "url": "https://alliancegenome.org/gene/RGD:3254#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9BYZ8-1", "protein_name": "Regenerating islet-derived protein 4", "gene_name": "REG4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASRSMRLLLLLSCLAKTGVLGDIIMRPSCAPGWFYHKSNCYGYFRKLRNWSDAELECQSYGNGAHLASILSLKEASTIAEYISGYQRSQPIWIGLHDPQKRQQWQWIDGAMYLYRSWSGKSMGGNKHCAEMSSNNNFLTWSSNECNKRQHFLCKYRP", "length": 158 }, "evidence": [ { "id": "MGI:1914959", "url": "https://alliancegenome.org/gene/MGI:1914959#orthology", "database": "AGR" }, { "id": "HGNC:22977", "url": "https://alliancegenome.org/gene/HGNC:22977#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-438", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-438#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D8G5-1", "protein_name": "Regenerating islet-derived protein 4", "gene_name": "Reg4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASKGVRLLLLLSWVAGPEVLSDILRPSCAPGWFYYRSHCYGYFRKLRNWSHAELECQSYGNGSHLASVLNQKEASVISKYITGYQRNLPVWIGLHDPQKKQLWQWTDGSTNLYRRWNPRTKSEARHCAEMNPKDKFLTWNKNGCANRQHFLCKYKT", "length": 157 }, "evidence": [ { "id": "MGI:1914959", "url": "https://alliancegenome.org/gene/MGI:1914959#orthology", "database": "AGR" }, { "id": "HGNC:22977", "url": "https://alliancegenome.org/gene/HGNC:22977#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-438", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-438#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JKF4-1", "protein_name": "C-type lectin domain family 6 member A", "gene_name": "Clec6a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVQERQSQGKGVCWTLRLWSAAVISMLLLSTCFIASCVVTYQFIMDQPSRRLYELHTYHSSLTCFSEGTMVSEKMWGCCPNHWKSFGSSCYLISTKENFWSTSEQNCVQMGAHLVVINTEAEQNFITQQLNESLSYFLGLSDPQGNGKWQWIDDTPFSQNVRFWHPHEPNLPEERCVSIVYWNPSKWGWNDVFCDSKHNSICEMKKIYL", "length": 209 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-438", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-438#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VLM0-1", "protein_name": "Lectin-29Ca", "gene_name": "lectin-29Ca", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MYKYATCIFSIFALWNFWGVSAKKQDTSTGTNELPKAPMPYYTIENIDMHQQHWFTYNSLRQNGTLWRIGNMEQRLEMRLQSFQNQMETKLRALKQQIEPYMENVKMSNKIKMSVFKKIGSRHFYLEKQKKMPWDSAYDTCRQMGGHLANILDEKELNEIFSEETKKKYWVDINSRANDGASWISTLSGRDVPFLKWKPNLATNIHNHCVYINSNEMYFENCANDNYFACQAEQWA", "length": 236 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VM16-1", "protein_name": "C-type lectin domain-containing protein", "gene_name": "Dmel\\CG15818", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFSSTRIILCAFLLLYPYGSLIEAQEGRRYVCLLSDPPNQCSEYCVSALQPVIDHLSKEQQDWGACEVKLNGSVAKLDKIEDQLTATQIQIEAQQAFLVNNISKAIKTEDLEQKLKDIEGNQTALSNQLKDGQKRTENQLTAIQKTLSDIERKLVLQRYQQIGSRYFYIEHNLQVNWRTAEQRCIEMGGHLAAFQNAEEYNAIVGQLNKANYWLGVNDLAKQGEFISLASGKRATYFKWRKNEPKYNNPTQHCAYVFGHENIMIVLSCTTDVMHFICQSDSDV", "length": 283 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VPS1-1", "protein_name": "Lectin-21Cb", "gene_name": "lectin-21Cb", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFKYDTYFLYLIVLLDPQGAQENNCPKVSLSERLEKRGEFSLVEFDPLLKFIVKNPHKELLGEIEGLVGHTENKLQPMKSVIPNQSKALLNYLDLHSKLEYLDAALQKAINSLQCSLKNTKVMSTGKPHPEFQKLGSRYFYIERHVRQNWFDAADKCRRMGGHLATPQDEDELYLIRKQLEARWFWLDISNLVDKDQYISLATGKEVSYLKWRHGEPKKSSTANCAYLYAGDYYTYQCSDRNFFICQAV", "length": 249 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VPS2-1", "protein_name": "Lectin-21Ca", "gene_name": "lectin-21Ca", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFQHANFFLHVFMACGLYGIRAKDVCPRMSTDKEVCLVELAPVLKYISNNHKSHWNSANEVQVNETRKQLAKIEGQEKETNDKIKVIHDNVDNEFNALSAKIKNVKNIQRHLASLELQLQETKKALNLSVEAKKVMPKTEIPSQFQKIGWRHFFIEKKHKVDWFKATSMCHKMGAHLLTIQSEDELDAIRTELKDINDGSHDFWLDINDIAKWGEFISLATGMNPPFLKWHKHRPQVQIHQRCVHLRGGEMMDGKCSEQFLFICQLAVN", "length": 269 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VQU4-1", "protein_name": "Lectin-24A", "gene_name": "lectin-24A", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFRLSVLVLNLLLVSHEFSAGTAKIEIQPLPALCNGYCFPTLKPVMEYVAIHQDKWNTCTEILANEARKDQIQLNIQLDALKADVSNIKASQLSKDEKLDRMEREQFAMHESLETINRYLTVKLDRTKLQLEAIKNTMDYMKAQMDGYFSAINGVQCLQPGFEKIGDRYFYIEEDVELNWLDAQAKCRRMGGHLASIKTKQEFDAIVEKLDDSKSYFLGVNENTKTGDFVSAASGKSCLYHEWGPGEPHHNNDQERCVSILRKLMHVGNCTYEKRFICQYGI", "length": 282 }, "evidence": [ { "id": "MGI:1861231", "url": "https://alliancegenome.org/gene/MGI:1861231#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0S6P2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6P2" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 145, "start_aa": "Phe", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0S6R2-1", "uniprot_ac": "B0S6R2", "uniprot_id": "B0S6R2_DANRE", "mass": { "chemical_mass": 23784.0, "monoisotopic_mass": 23784.0 }, "refseq": { "ac": "NP_001121737", "name": "dual specificity protein phosphatase 19", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121737" }, "gene_names": [ { "name": "dusp19a", "type": "recommended", "evidence": [ { "id": "B0S6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6R2" } ] }, { "name": "dusp19a", "type": "synonym", "evidence": [ { "id": "NP_001121737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121737" } ] }, { "name": "dusp19", "type": "synonym", "evidence": [ { "id": "NP_001121737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121737" }, { "id": "B0S6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6R2" } ] }, { "name": "si:dkey-237j22.1", "type": "synonym", "evidence": [ { "id": "NP_001121737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121737" }, { "id": "B0S6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6R2" } ] } ], "protein_names": [ { "name": "3.1.3.48", "type": "synonym", "evidence": [ { "id": "B0S6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6R2/entry#names_and_taxonomy" } ] }, { "name": "Dual specificity protein phosphatase 19", "type": "synonym", "evidence": [ { "id": "B0S6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6R2/entry#names_and_taxonomy" } ] }, { "name": "dual specificity phosphatase 19", "type": "synonym", "evidence": [ { "id": "NP_001121737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121737" } ] }, { "name": "dual specificity protein phosphatase 19", "type": "synonym", "evidence": [ { "id": "NP_001121737", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121737" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH577333.1, EH556232.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA3505380 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000009.1. On Jul 31, 2008 this sequence version replaced XP_001332412.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001121737", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121737" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S6R2", "url": "https://www.uniprot.org/uniprotkb/B0S6R2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dusp19a", "url": "https://www.uniprot.org/uniprotkb/B0S6R2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-382", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-382", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000040490", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000040490", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14523", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14523", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "792815", "url": "https://www.ncbi.nlm.nih.gov/gene/792815", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000340", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000340", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000387", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000387", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR020422", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020422", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029021", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029021", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:792815", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:792815", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQDNNWD", "url": "https://omabrowser.org/oma/group/VQDNNWD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S6R2", "url": "https://www.orthodb.org/?gene=B0S6R2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46377", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46377", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46377:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46377:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00782", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00782", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001121737", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001121737", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S6R2", "url": "https://www.uniprot.org/uniprotkb/B0S6R2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S6R2-1", "url": "https://www.uniprot.org/uniprotkb/B0S6R2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-382", "url": "https://zfin.org/ZDB-GENE-081104-382", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MQSLAQEIKSFSKTNLRKQCTRVTTLSGRRIIETWKGSIVQVVEETVQPETPCGYVQDNNWDLQVGYVKPYLLLGSQDAAHDFATLRKYKVTHILNVAYGVENAFPDLFIYKTLSILDQPDTDIISHIKECAQFIDQAKNEKGVVLVHCNSGVSRSVSVVIGYLMLKENQGFGDTFALVKSARPASCPNPGFMEQLKNFKPQDVTQANGLSHD", "length": 213, "header": "tr|B0S6R2-1|B0S6R2_DANRE Isoform 1 of Dual specificity protein phosphatase 19 OS=Danio rerio OX=7955 GN=dusp19a PE=4 SV=1 CANONICAL=B0S6R2-1" }, "isoforms": [ { "isoform_ac": "B0S6R2-1", "url": "https://www.uniprot.org/uniprotkb/B0S6R2/entry#B0S6R2-1", "sequence": { "sequence": "MQSLAQEIKSFSKTNLRKQCTRVTTLSGRRIIETWKGSIVQVVEETVQPETPCGYVQDNNWDLQVGYVKPYLLLGSQDAAHDFATLRKYKVTHILNVAYGVENAFPDLFIYKTLSILDQPDTDIISHIKECAQFIDQAKNEKGVVLVHCNSGVSRSVSVVIGYLMLKENQGFGDTFALVKSARPASCPNPGFMEQLKNFKPQDVTQANGLSHD", "length": 213, "header": "tr|B0S6R2-1|B0S6R2_DANRE Isoform 1 of Dual specificity protein phosphatase 19 OS=Danio rerio OX=7955 GN=dusp19a PE=4 SV=1 CANONICAL=B0S6R2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "CERKL knockdown causes retinal degeneration in zebrafish.", "journal": "PLoS ONE", "date": "2013", "authors": "Riera Marina, Burguera Demian, Garcia-Fern\u00e0ndez Jordi, Gonz\u00e0lez-Duarte Roser", "evidence": [ { "database": "UniProtKB", "id": "B0S6R2", "url": "https://www.uniprot.org/uniprotkb/B0S6R2" } ], "reference": [ { "type": "PubMed", "id": "23671706", "url": "https://glygen.org/publication/PubMed/23671706" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0S6R2", "url": "https://www.uniprot.org/uniprotkb/B0S6R2" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:792815", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:792815", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M1PN11-1", "protein_name": "protein-serine/threonine phosphatase", "gene_name": "dusp19b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSLAQEIAGFSTSRLRKQSTRVTTASGQVLLETRSGADYHSTPDTERQSADTCGFVQDFSLDLQVGIITPFLLLSSQDAAHDIDTLKKLKVTHVLNVAFGVENAFPELFTYKTVSMLDLPETDITAYFPECFEFITQARQQDGVVLVHCNAGVSRSASVVIGFLMSELKMSFDEAFSVAKTSRPQIQPNPGFLQQLKTYNPA", "length": 203 }, "evidence": [ { "id": "MGI:1915332", "url": "https://alliancegenome.org/gene/MGI:1915332#orthology", "database": "AGR" }, { "id": "HGNC:18894", "url": "https://alliancegenome.org/gene/HGNC:18894#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K4T5-1", "protein_name": "Dual specificity protein phosphatase 19", "gene_name": "Dusp19", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MHSLNQKIKAFSRDNLRKQCTRVTTLTGKKLIETWEDATVHVVETEPSGGGGCGYVQDLTLDLQVGVIKPWLLLGSQDAAHDLELLRKHKVTHILNVAYGVENAFLSEFTYKTISILDVPETNILSYFPECFEFIEQAKLKDGVVLVHCNAGVSRAAAIVIGFLMSSEEATFTTALSLVKEARPSICPNPGFMEQLRTYQVGKESNGGDKVPAEDTTHGL", "length": 220 }, "evidence": [ { "id": "MGI:1915332", "url": "https://alliancegenome.org/gene/MGI:1915332#orthology", "database": "AGR" }, { "id": "HGNC:18894", "url": "https://alliancegenome.org/gene/HGNC:18894#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-382", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-382#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8WTR2-1", "protein_name": "Dual specificity protein phosphatase 19", "gene_name": "DUSP19", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYSLNQEIKAFSRNNLRKQCTRVTTLTGKKIIETWKDARIHVVEEVEPSSGGGCGYVQDLSSDLQVGVIKPWLLLGSQDAAHDLDTLKKNKVTHILNVAYGVENAFLSDFTYKSISILDLPETNILSYFPECFEFIEEAKRKDGVVLVHCNAGVSRAAAIVIGFLMNSEQTSFTSAFSLVKNARPSICPNSGFMEQLRTYQEGKESNKCDRIQENSS", "length": 217 }, "evidence": [ { "id": "MGI:1915332", "url": "https://alliancegenome.org/gene/MGI:1915332#orthology", "database": "AGR" }, { "id": "HGNC:18894", "url": "https://alliancegenome.org/gene/HGNC:18894#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-382", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-382#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "JUN kinase phosphatase activity", "id": "GO:0008579", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008579", "evidence": [ { "database": "UniProtKB", "id": "B0S6R2", "url": "https://www.uniprot.org/uniprotkb/B0S6R2" } ], "pmid": "" }, { "name": "protein tyrosine phosphatase activity", "id": "GO:0004725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004725", "evidence": [ { "database": "UniProtKB", "id": "B0S6R2", "url": "https://www.uniprot.org/uniprotkb/B0S6R2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B0S6R2", "url": "https://www.uniprot.org/uniprotkb/B0S6R2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of JNK cascade", "id": "GO:0046328", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046328", "evidence": [ { "database": "UniProtKB", "id": "B0S6R2", "url": "https://www.uniprot.org/uniprotkb/B0S6R2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0S6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6R2" }, { "id": "PS50056", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50056" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine specific protein phosphatases", "eco_id": "ECO_0000259", "start_pos": 122, "end_pos": 184, "start_aa": "Thr", "end_aa": "Pro", "glycosite_overlap": "" }, { "evidence": [ { "id": "B0S6R2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6R2" }, { "id": "PS50054", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50054" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Tyrosine-protein phosphatase", "eco_id": "ECO_0000259", "start_pos": 64, "end_pos": 205, "start_aa": "Gln", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "3.1.3.48", "ec_name": "O-phospho-L-tyrosyl-[protein] + H2O = L-tyrosyl-[protein] + phosphate.", "evidence": [ { "id": "3.1.3.48", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:3.1.3.48" }, { "id": "3.1.3.48", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=3.1.3.48" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0S6R8-1", "uniprot_ac": "B0S6R8", "uniprot_id": "B0S6R8_DANRE", "mass": { "chemical_mass": 64865.0, "monoisotopic_mass": 64865.0 }, "refseq": { "ac": "NP_001352897", "name": "finTRIM family, member 24", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352897" }, "gene_names": [ { "name": "ftr24", "type": "recommended", "evidence": [ { "id": "B0S6R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6R8" } ] }, { "name": "ftr24", "type": "synonym", "evidence": [ { "id": "NP_001352897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352897" } ] }, { "name": "zgc:114036", "type": "synonym", "evidence": [ { "id": "NP_001352897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352897" }, { "id": "B0S6R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6R8" } ] } ], "protein_names": [ { "name": "FinTRIM family, member 24", "type": "synonym", "evidence": [ { "id": "B0S6R8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6R8/entry#names_and_taxonomy" } ] }, { "name": "finTRIM family, member 24", "type": "synonym", "evidence": [ { "id": "NP_001352897", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352897" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01010898.1, SRR26395012.1260502.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On Jun 25, 2025 this sequence version replaced NP_001352897.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001352897", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352897" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S6R8", "url": "https://www.uniprot.org/uniprotkb/B0S6R8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ftr24", "url": "https://www.uniprot.org/uniprotkb/B0S6R8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050731-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050731-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd16040", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd16040", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd19769", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd19769", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "IPR000315", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000315", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001841", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001841", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013083", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013083", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017907", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017907", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051051", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051051", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058030", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058030", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:110437704", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437704", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "B0S6R8", "url": "https://www.orthodb.org/?gene=B0S6R8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR25465:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR25465:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00622", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00622", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF00643", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00643", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF15227", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15227", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25600", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25600", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001352897", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001352897", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S6R8", "url": "https://www.uniprot.org/uniprotkb/B0S6R8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S6R8-1", "url": "https://www.uniprot.org/uniprotkb/B0S6R8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050731-2", "url": "https://zfin.org/ZDB-GENE-050731-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAEANISVAEDQFNCSICLDLLREPVTIPCGHSYCMNCITDYWNQNDQRRVYSCPQCRETFTPRPALNKNVMFAEIVQKLRGASFQTAPALSYAGPGDVECDVCTERKYKAVKSCLACLQSYCQTHFERHEEFHSGRHKVTKATGQLKQMICPKHDKLLEVYCRTDQKCICLLCTVDEHKNHDTVSTTSERTDIQKQLEETQAHFQQKIQEREKRMQELKDAVKTNRHLAQAAEKDSEEIFAELIRFIERSRSEVIWRIRNQEKDAKSEVEGLLKELEQEIEDLKWRNTELEQLLHTDDHIHFLQRFQSLCEPSKMTDISRANVSSVLLNEDVGRSVSQLKEKLEQFCKEEIENIFYKEAKINRAYQTEPKTRKDFLQYFLQLSLDRNTAHQSLCLSEGNTVATYTHTAQHLPDHPDRFTNFFGVLCRESVSGRCYWEVESIGNERLYGVGVAVSYKSINRKGTRTTSGFGYNDQSWKMICSRSRYIFWHNNIKTKLPALFRSSRIGVYVDHRAGVLSFFSVSDTTMNLIHRVQTTFTQPLYPGFWIDPGSRLKICRL", "length": 558, "header": "tr|B0S6R8-1|B0S6R8_DANRE Isoform 1 of FinTRIM family, member 24 OS=Danio rerio OX=7955 GN=ftr24 PE=4 SV=1 CANONICAL=B0S6R8-1" }, "isoforms": [ { "isoform_ac": "B0S6R8-1", "url": "https://www.uniprot.org/uniprotkb/B0S6R8/entry#B0S6R8-1", "sequence": { "sequence": "MAEANISVAEDQFNCSICLDLLREPVTIPCGHSYCMNCITDYWNQNDQRRVYSCPQCRETFTPRPALNKNVMFAEIVQKLRGASFQTAPALSYAGPGDVECDVCTERKYKAVKSCLACLQSYCQTHFERHEEFHSGRHKVTKATGQLKQMICPKHDKLLEVYCRTDQKCICLLCTVDEHKNHDTVSTTSERTDIQKQLEETQAHFQQKIQEREKRMQELKDAVKTNRHLAQAAEKDSEEIFAELIRFIERSRSEVIWRIRNQEKDAKSEVEGLLKELEQEIEDLKWRNTELEQLLHTDDHIHFLQRFQSLCEPSKMTDISRANVSSVLLNEDVGRSVSQLKEKLEQFCKEEIENIFYKEAKINRAYQTEPKTRKDFLQYFLQLSLDRNTAHQSLCLSEGNTVATYTHTAQHLPDHPDRFTNFFGVLCRESVSGRCYWEVESIGNERLYGVGVAVSYKSINRKGTRTTSGFGYNDQSWKMICSRSRYIFWHNNIKTKLPALFRSSRIGVYVDHRAGVLSFFSVSDTTMNLIHRVQTTFTQPLYPGFWIDPGSRLKICRL", "length": 558, "header": "tr|B0S6R8-1|B0S6R8_DANRE Isoform 1 of FinTRIM family, member 24 OS=Danio rerio OX=7955 GN=ftr24 PE=4 SV=1 CANONICAL=B0S6R8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A large new subset of TRIM genes highly diversified by duplication and positive selection in teleost fish.", "journal": "BMC Biol.", "date": "2009", "authors": "van der Aa Lieke M, Levraud Jean-Pierre, Yahmi Malika, Lauret Emilie, Briolat Val\u00e9rie, Herbomel Philippe, Benmansour Abdenour, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "B0S6R8", "url": "https://www.uniprot.org/uniprotkb/B0S6R8" } ], "reference": [ { "type": "PubMed", "id": "19196451", "url": "https://glygen.org/publication/PubMed/19196451" } ] }, { "title": "Origin and evolution of TRIM proteins: new insights from the complete TRIM repertoire of zebrafish and pufferfish.", "journal": "PLoS ONE", "date": "2011", "authors": "Boudinot Pierre, van der Aa Lieke M, Jouneau Luc, Du Pasquier Louis, Pontarotti Pierre, Briolat Val\u00e9rie, Benmansour Abdenour, Levraud Jean-Pierre", "evidence": [ { "database": "UniProtKB", "id": "B0S6R8", "url": "https://www.uniprot.org/uniprotkb/B0S6R8" } ], "reference": [ { "type": "PubMed", "id": "21789205", "url": "https://glygen.org/publication/PubMed/21789205" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B0S6R8", "url": "https://www.uniprot.org/uniprotkb/B0S6R8" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Fish antiviral tripartite motif (TRIM) proteins.", "journal": "Fish Shellfish Immunol.", "date": "2019", "authors": "Langevin Christelle, Levraud Jean-Pierre, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "B0S6R8", "url": "https://www.uniprot.org/uniprotkb/B0S6R8" } ], "reference": [ { "type": "PubMed", "id": "30550990", "url": "https://glygen.org/publication/PubMed/30550990" } ] } ], "pathway": [ { "id": "dre:110437704", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:110437704", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B0S6R8", "url": "https://www.uniprot.org/uniprotkb/B0S6R8" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B0S6R8", "url": "https://www.uniprot.org/uniprotkb/B0S6R8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "innate immune response", "id": "GO:0045087", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045087", "evidence": [ { "database": "UniProtKB", "id": "B0S6R8", "url": 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"start_pos": 14, "end_pos": 16 }, { "start_pos": 323, "end_pos": 325 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", 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"type": "synonym", "evidence": [ { "id": "B0S6V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S6V5/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkey-10c21.1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001341146", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001341146" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001341146", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001341146" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S6V5", "url": "https://www.uniprot.org/uniprotkb/B0S6V5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-10c21.1", "url": "https://www.uniprot.org/uniprotkb/B0S6V5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-302", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-302", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000079133", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000079133", "database": "Bgee", "categories": [ "Gene 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"database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S6V5", "url": "https://www.orthodb.org/?gene=B0S6V5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46985", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46985", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46985:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46985:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00619", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00619", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-111458", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-111458", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-844455", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-844455", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, 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The reference sequence was derived from JBMGRA010000009.1. On Mar 17, 2008 this sequence version replaced XP_001335009.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001116179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116179" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S6Z7", "url": "https://www.uniprot.org/uniprotkb/B0S6Z7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-18p12.4", "url": "https://www.uniprot.org/uniprotkb/B0S6Z7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-408", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-408", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000079703", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000079703", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd13733", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd13733", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "794946", "url": "https://www.ncbi.nlm.nih.gov/gene/794946", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001870", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001870", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003877", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003877", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003879", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003879", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": 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"database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13765", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13765", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001116179", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116179", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S6Z7", "url": "https://www.uniprot.org/uniprotkb/B0S6Z7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S6Z7-1", "url": "https://www.uniprot.org/uniprotkb/B0S6Z7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-408", "url": "https://zfin.org/ZDB-GENE-070912-408", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAFAATKENNTGITLSDISIQEPYLRNRRYSASFPFIKPELSDQPKQKVVQILKDLGLVCYQVFKIPAIRSTEQKEDFSLDESKCIIRELAAELDRVVQSKILLMTEKIKSKGTNDEEQKEQEYYIFQWAEDVENMQIKQLDNKKEQQPFSEHLTNSEKRFKKAKTILSDWSWTLKNMQQNSVCPKGECEEILKDLHRQWKQGESSILPVMDWMIWTVLQSERSQDSVARQWIRSKQRSRNTAGLCIPKPVWNWITTSTDVVVLDPNTANPELLVSDDGKYLKSKKYTGLDNWEGFQRKKCRFDGWACVQAKEGYSTGRHYWEVGVKKKHEWRVGVVKESAPRNGYVNMNTKAGYWNLRLQLGTVMALTEPVTKLNVQSPSKIGVYLDIEEGHVSFYDAEKQRHIYTFNTDFNETENIYPMFGTVETDRALVILS", "length": 435, "header": "tr|B0S6Z7-1|B0S6Z7_DANRE Isoform 1 of SPRY_PRY_C-I_1 domain-containing protein OS=Danio rerio OX=7955 GN=si:dkey-18p12.4 PE=4 SV=1 CANONICAL=B0S6Z7-1" }, "isoforms": [ { "isoform_ac": "B0S6Z7-1", "url": "https://www.uniprot.org/uniprotkb/B0S6Z7/entry#B0S6Z7-1", "sequence": { "sequence": 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"sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0S784-1", "uniprot_ac": "B0S784", "uniprot_id": "B0S784_DANRE", "mass": { "chemical_mass": 20933.0, "monoisotopic_mass": 20933.0 }, "refseq": { "ac": "NP_001013554", "name": "Receptor expression-enhancing protein 6-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013554" }, "gene_names": [ { "name": "zgc:101744", "type": "synonym", "evidence": [ { "id": "NP_001013554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013554" }, { "id": "B0S784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S784" } ] } ], "protein_names": [ { "name": "Receptor expression-enhancing protein", "type": "recommended", "evidence": [ { "id": "B0S784", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S784/entry#names_and_taxonomy" } ] }, { "name": "Receptor expression-enhancing protein 6-like", "type": "synonym", "evidence": [ { "id": "NP_001013554", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013554" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01004130.1, GDQQ01000784.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505372, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. On or before May 20, 2009 this sequence version replaced NP_001119913.1, NP_001013554.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001013554", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013554" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S784", "url": "https://www.uniprot.org/uniprotkb/B0S784" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "", "url": "https://www.uniprot.org/uniprotkb/B0S784", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050320-111", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050320-111", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000038694", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000038694", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "541409", "url": "https://www.ncbi.nlm.nih.gov/gene/541409", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR004345", "url": "https://www.ebi.ac.uk/interpro/entry/IPR004345", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:541409", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:541409", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GLYMVFG", "url": "https://omabrowser.org/oma/group/GLYMVFG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S784", "url": "https://www.orthodb.org/?gene=B0S784", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12300", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12300", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12300:SF133", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12300:SF133", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001013554", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001013554", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S784", "url": "https://www.uniprot.org/uniprotkb/B0S784", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S784-1", "url": "https://www.uniprot.org/uniprotkb/B0S784-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050320-111", "url": "https://zfin.org/ZDB-GENE-050320-111", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLNTVTERYDAFFKQKNVLTDFLAVLEEKTGVQKQYIAAGVVSIVAFYLIFGYGASLLCNLIGFIYPAYASIKAIESNNKEDDTKWLTYWVVYGLFSVAEFFSDIFLFWFPFYYAGKCLFLLWCMAPISWNGSQVIYTRVVRPFFLKHEAAFDNVVSDLSGKAKSAAETMAKEGLTLLNSDKNK", "length": 184, "header": "tr|B0S784-1|B0S784_DANRE Isoform 1 of Receptor expression-enhancing protein OS=Danio rerio OX=7955 GN= PE=1 SV=1 CANONICAL=B0S784-1" }, "isoforms": [ { "isoform_ac": "B0S784-1", "url": "https://www.uniprot.org/uniprotkb/B0S784/entry#B0S784-1", "sequence": { "sequence": "MLNTVTERYDAFFKQKNVLTDFLAVLEEKTGVQKQYIAAGVVSIVAFYLIFGYGASLLCNLIGFIYPAYASIKAIESNNKEDDTKWLTYWVVYGLFSVAEFFSDIFLFWFPFYYAGKCLFLLWCMAPISWNGSQVIYTRVVRPFFLKHEAAFDNVVSDLSGKAKSAAETMAKEGLTLLNSDKNK", "length": 184, "header": "tr|B0S784-1|B0S784_DANRE Isoform 1 of Receptor expression-enhancing protein OS=Danio rerio OX=7955 GN= PE=1 SV=1 CANONICAL=B0S784-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0S784", "url": "https://www.uniprot.org/uniprotkb/B0S784" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "B0S784", "url": "https://www.uniprot.org/uniprotkb/B0S784" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] } ], "pathway": [ { "id": "dre:541409", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:541409", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "endoplasmic reticulum membrane", "id": "GO:0005789", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005789", "evidence": [ { "database": "UniProtKB", "id": "B0S784", "url": "https://www.uniprot.org/uniprotkb/B0S784" } ], "pmid": "" }, { "name": "clathrin-coated vesicle membrane", "id": "GO:0030665", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030665", "evidence": [ { "database": "UniProtKB", "id": "B0S784", "url": "https://www.uniprot.org/uniprotkb/B0S784" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 131, "end_pos": 133, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 131, "end_pos": 133 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0S7I8-1", "uniprot_ac": "B0S7I8", "uniprot_id": "B0S7I8_DANRE", "mass": { "chemical_mass": 41774.0, "monoisotopic_mass": 41774.0 }, "refseq": { "ac": "XP_005167494", "name": "probable G-protein coupled receptor 45", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167494" }, "gene_names": [ { "name": "gpr45", "type": "recommended", "evidence": [ { "id": "B0S7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7I8" } ] }, { "name": "gpr45", "type": "synonym", "evidence": [ { "id": "XP_005167494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167494" } ] } ], "protein_names": [ { "name": "Probable G-protein coupled receptor 45", "type": "synonym", "evidence": [ { "id": "B0S7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7I8/entry#names_and_taxonomy" } ] }, { "name": "probable G-protein coupled receptor 45", "type": "synonym", "evidence": [ { "id": "XP_005167494", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167494" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005167494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167494" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S7I8", "url": "https://www.uniprot.org/uniprotkb/B0S7I8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gpr45", "url": "https://www.uniprot.org/uniprotkb/B0S7I8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-629", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-629", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000063357", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000063357", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "795372", "url": "https://www.ncbi.nlm.nih.gov/gene/795372", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051880", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051880", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:795372", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795372", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WHFGDYF", "url": "https://omabrowser.org/oma/group/WHFGDYF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0S7I8", "url": "https://www.orthodb.org/?gene=B0S7I8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24245", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24245", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24245:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24245:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005167494", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167494", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0S7I8", "url": "https://www.uniprot.org/uniprotkb/B0S7I8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S7I8-1", "url": "https://www.uniprot.org/uniprotkb/B0S7I8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-629", "url": "https://zfin.org/ZDB-GENE-070912-629", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFACNGSSLEACGLLEPTETEMQEADTALMPTTLRVALAAIMIFMITIGFLGNGIVCLIVYQKPAMRSAINLLLATLAFSDIMLSLLCMPFTAVTLATTDWSFGMGFCRVSVMLYWLFVLEGVSILLIISVDRFLIIVQRQDKLTPHRAKILIGASWALSLCVSLPSLVGWRTAGIGAQVPQCILGYSESLADRGYTVLLAVAVFFVPFGVMLYSYLCILNTVRRNALRIHNHTSEGSVAISHVSKLGLTGLQRPQVNIDMSFKTRAFTTILILFIGFSVCWLPHTVVSLLSVFSRRFYLSPAFYPVSIGALWLSYLKAVFNPVIYCWRIRKFREACLEFMPKTFHLCPKIPGRSRRRIRPSNIYVCSSETQSSV", "length": 375, "header": "tr|B0S7I8-1|B0S7I8_DANRE Isoform 1 of Probable G-protein coupled receptor 45 OS=Danio rerio OX=7955 GN=gpr45 PE=4 SV=1 CANONICAL=B0S7I8-1" }, "isoforms": [ { "isoform_ac": "B0S7I8-1", "url": "https://www.uniprot.org/uniprotkb/B0S7I8/entry#B0S7I8-1", "sequence": { "sequence": "MFACNGSSLEACGLLEPTETEMQEADTALMPTTLRVALAAIMIFMITIGFLGNGIVCLIVYQKPAMRSAINLLLATLAFSDIMLSLLCMPFTAVTLATTDWSFGMGFCRVSVMLYWLFVLEGVSILLIISVDRFLIIVQRQDKLTPHRAKILIGASWALSLCVSLPSLVGWRTAGIGAQVPQCILGYSESLADRGYTVLLAVAVFFVPFGVMLYSYLCILNTVRRNALRIHNHTSEGSVAISHVSKLGLTGLQRPQVNIDMSFKTRAFTTILILFIGFSVCWLPHTVVSLLSVFSRRFYLSPAFYPVSIGALWLSYLKAVFNPVIYCWRIRKFREACLEFMPKTFHLCPKIPGRSRRRIRPSNIYVCSSETQSSV", "length": 375, "header": "tr|B0S7I8-1|B0S7I8_DANRE Isoform 1 of Probable G-protein coupled receptor 45 OS=Danio rerio OX=7955 GN=gpr45 PE=4 SV=1 CANONICAL=B0S7I8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:795372", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795372", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A8X5-1", "protein_name": "G protein-coupled receptor 45", "gene_name": "Gpr45", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MACNSTPIGTYQHLLLNASNTLDPGATPLSAPLRISLAIMMLLMIVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAITLVTVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRAKVIIAASWVLSFCISAPSFTGWTFMEVPARAPQCVLGYTEFPAERAYVVTLVVAVFFAPFGVMLCSYLCILNTVRKNAVRVHNQSDSLDLRHLSGAGLRRLRRQQQQASLDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSAFSRRFYYSASFYTTSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPQTFQILPKVPERIQRKIQPSTVYVCNENQSTV", "length": 373 }, "evidence": [ { "id": "MGI:2135882", "url": "https://alliancegenome.org/gene/MGI:2135882#orthology", "database": "AGR" }, { "id": "HGNC:4503", "url": "https://alliancegenome.org/gene/HGNC:4503#orthology", "database": "AGR" }, { "id": "B0S7I8", "url": "https://omabrowser.org/oma/group/B0S7I8/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H5N8-1", "protein_name": "Probable G-protein coupled receptor 45", "gene_name": "Gpr45", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MACNSTSIGTNEHLLLNASKASDPGATPLSAPLRISLAITMLLMIVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAITLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRAKAIIAASWVLSFCISAPSFTGWTFMEVPARAPQCVLGYTEFPGERAYVVMLVVAVFFAPFGVMLCSYLCILNTVRKNAVRVRNQSESLDLKQMSRAGLRRLRRQQQQVSLDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSAFSRRFYYSASFYTTSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPQTFQILPKVPERIQRKIQPSTVYVCNENQSAV", "length": 373 }, "evidence": [ { "id": "B0S7I8", "url": "https://omabrowser.org/oma/group/B0S7I8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "I3L989-1", "protein_name": "G protein-coupled receptor 45", "gene_name": "GPR45", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKCRSQPVLPKKDAPPGPSGSLEIPDSREEDAAGRQSAAAPQALRAPSTPSGPSPRISSTMACNSTSIQTEESAPRNGSLGEDSRAPAPLRMSLAVVMMLMIVVGFLGNAVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAVTLITVHWHFGDYFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDRLNPRRAKVIIAASWALSFCVSAPSLAGWTLVEVPARAPQCVLGYTEGPGGRAYVLVLVGAAFFVPFAVMLCSYLGILHTVRKNAVRVHNQSDSLDLRRLPRAGLRRLQRHQQVSLDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSRRFYCGPSFYTTSSCVLWLSYLKSVFNPIVYCWKIKKFREACLELLPQTFQILPKVPERIRRRIQPSTIYACPENQSAV", "length": 429 }, "evidence": [ { "id": "B0S7I8", "url": "https://omabrowser.org/oma/group/B0S7I8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q9EQQ4-1", "protein_name": "Protein carrier GPR45", "gene_name": "Gpr45", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MACNSTPMGTYEHLLLNVSNTLDPGDTPLSAPLRISLAIMMLLMIVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAITLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRAKMIIAASWVLSFCISAPSFTGWTFMEVPARAPQCVLGYTEFPAERAYVVTLVVAVFFAPFGVMLCSYLCILNTVRKNAVRVHNQSDSLDLRQLTGAGLRRLRRQQQQASLDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSAFSRRFYYSASFYTTSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPHTFQILPKVPERIQRKIQPSTIYVCNENQSAV", "length": 373 }, "evidence": [ { "id": "MGI:2135882", "url": "https://alliancegenome.org/gene/MGI:2135882#orthology", "database": "AGR" }, { "id": "HGNC:4503", "url": "https://alliancegenome.org/gene/HGNC:4503#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-629", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-629#orthology", "database": "AGR" }, { "id": "B0S7I8", "url": "https://omabrowser.org/oma/group/B0S7I8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9Y5Y3-1", "protein_name": "Probable G protein-coupled receptor 45", "gene_name": "GPR45", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MACNSTSLEAYTYLLLNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPQTFQILPKVPERIRRRIQPSTVYVCNENQSAV", "length": 372 }, "evidence": [ { "id": "MGI:2135882", "url": "https://alliancegenome.org/gene/MGI:2135882#orthology", "database": "AGR" }, { "id": "HGNC:4503", "url": "https://alliancegenome.org/gene/HGNC:4503#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-629", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-629#orthology", "database": "AGR" }, { "id": "B0S7I8", "url": "https://omabrowser.org/oma/group/B0S7I8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "B0S7I8", "url": "https://www.uniprot.org/uniprotkb/B0S7I8" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B0S7I8", "url": "https://www.uniprot.org/uniprotkb/B0S7I8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "B0S7I8", "url": "https://www.uniprot.org/uniprotkb/B0S7I8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 232, "end_pos": 234, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0S7I8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7I8" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 326, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 232, "end_pos": 234 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0S7L0-1", "uniprot_ac": "B0S7L0", "uniprot_id": "B0S7L0_DANRE", "mass": { "chemical_mass": 56042.0, "monoisotopic_mass": 56042.0 }, "refseq": { "ac": "NP_955911", "name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_955911" }, "gene_names": [ { "name": "dus1l", "type": "recommended", "evidence": [ { "id": "B0S7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ] }, { "name": "dus1l", "type": "synonym", "evidence": [ { "id": "NP_955911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_955911" } ] }, { "name": "wu:fb71f06", "type": "synonym", "evidence": [ { "id": "NP_955911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_955911" }, { "id": "B0S7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ] }, { "name": "zgc:63748", "type": "synonym", "evidence": [ { "id": "NP_955911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_955911" }, { "id": "B0S7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ] } ], "protein_names": [ { "name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "type": "recommended", "evidence": [ { "id": "B0S7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7L0/entry#names_and_taxonomy" } ] }, { "name": "1.3.1.88", "type": "synonym", "evidence": [ { "id": "B0S7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7L0/entry#names_and_taxonomy" } ] }, { "name": "tRNA-dihydrouridine synthase 1-like", "type": "synonym", "evidence": [ { "id": "B0S7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7L0/entry#names_and_taxonomy" } ] }, { "name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "type": "synonym", "evidence": [ { "id": "NP_955911", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_955911" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC058873.1, GDQQ01010101.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476730, SAMEA4476736 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000003.1, EH452764.1, EH592252.1 and EH524077.1. On Jan 28, 2016 this sequence version replaced NP_955911.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_955911", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_955911" } ] }, { "annotation": "Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U16 and U17 in cytoplasmic tRNAs. Affects the level of some mature tRNA and thereby the total cellular translation.", "evidence": [ { "database": "UniProtKB", "id": "B0S7L0", "url": "https://www.uniprot.org/uniprotkb/B0S7L0#function" }, { "database": "UniProtKB", "id": "ARBA00053643", "url": "https://www.uniprot.org/uniprotkb/ARBA00053643#function" }, { "database": "UniProtKB", "id": "A0AC58IDJ0", "url": "https://www.uniprot.org/uniprotkb/A0AC58IDJ0#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0S7L0", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dus1l", "url": "https://www.uniprot.org/uniprotkb/B0S7L0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-1435", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1435", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000089260", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000089260", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02801", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02801", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "322715", "url": "https://www.ncbi.nlm.nih.gov/gene/322715", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013785", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013785", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035587", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035587", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:322715", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:322715", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ISPPVWQ", "url": "https://omabrowser.org/oma/group/ISPPVWQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "A0AC58IDJ0", "url": "https://www.orthodb.org/?gene=A0AC58IDJ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "B0S7L0", "url": "https://www.orthodb.org/?gene=B0S7L0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11082", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11082", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11082:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11082:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01207", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01207", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_955911", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_955911", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "53368", "url": "https://www.rhea-db.org/rhea/53368", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53372", "url": "https://www.rhea-db.org/rhea/53372", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53376", "url": "https://www.rhea-db.org/rhea/53376", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "53380", "url": "https://www.rhea-db.org/rhea/53380", "database": "Rhea", "categories": [ "Enzyme and Pathway" ] }, { "id": "A0AC58IDJ0", "url": "https://www.uniprot.org/uniprotkb/A0AC58IDJ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IDJ0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IDJ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S7L0", "url": "https://www.uniprot.org/uniprotkb/B0S7L0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0S7L0-1", "url": "https://www.uniprot.org/uniprotkb/B0S7L0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-1435", "url": "https://zfin.org/ZDB-GENE-030131-1435", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MCRIYRSLAVPQATAGSMTKPLGFEFWRRTLKGARFVVAPMVDQSELAWRLLSRRHGAELCYTPMLHAQVFVRDANYRRENLYSEVNQEDRPLITQFCANDPEVFIQAALLAQDYCDAIDLNLGCPQMIAKRGHYGVFLQDEWDLLEKMIKLANEKLSVPITCKIRVFPEIEKTVKYAKMLEKAGCQLLTVHGRTKDQKGALTGIASWKHIKAVREAVNIPVFANGNIQHLSDVHHCMEETGVQGVMSAEGNLHNPALFEGRSPPVWEMAEEYLDIVEKHSPCSLSFVRAHIFKLWHHTLQIHQDLREDLAKAKNVDGIVEVNRQLKQRCQEEMAKDESEWNQTGLPFPHWICQPYVRPPPKDPNTENGQKSQETKAVSVKRALEDSDGPNDAMSKNKQKKKARNPHKNFCPELKPKYIKCEQCGNPKGNKCVFNLCRGCCKRKAFKEVADCPGHGLKFKTKALRQCNSDTSGGGLTNGKASTQTVSTAVHDPLQA", "length": 496, "header": "tr|B0S7L0-1|B0S7L0_DANRE Isoform 1 of tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like OS=Danio rerio OX=7955 GN=dus1l PE=1 SV=1 CANONICAL=B0S7L0-1" }, "isoforms": [ { "isoform_ac": "A0AC58IDJ0-1", "url": "https://www.uniprot.org/uniprotkb/B0S7L0/entry#A0AC58IDJ0-1", "sequence": { "sequence": "MTKPLGFEFWRRTLKGARFVVAPMVDQSELAWRLLSRRHGAELCYTPMLHAQVFVRDANYRRENLYSEVNQEDRPLITQFCANDPEVFIQAALLAQDYCDAIDLNLGCPQMIAKRGHYGVFLQDEWDLLEKMIKLANEKLSVPITCKIRVFPEIEKTVKYAKMLEKAGCQLLTVHGRTKDQKGALTGIASWKHIKAVREAVNIPVFANGNIQHLSDVHHCMEETGVQGVMSAEGNLHNPALFEGRSPPVWEMAEEYLDIVEKHSPCSLSFVRAHIFKLWHHTLQIHQDLREDLAKAKNVDGIVEVNRQLKQRCQEEMAKDESEWNQTGLPFPHWICQPYVRPPPKDPNTENGQKSQETKAVSVKRALEDSDGPNDAMSKNKQKKKARNPHKNFCPELKPKYIKCEQCGNPKGNKCVFNLCRGCCKRKAFKEVADCPGHGLKFKTKALRQCNSDTSGGGLTNGKASTQTVSTAVHDPLQA", "length": 479, "header": "tr|A0AC58IDJ0-1|A0AC58IDJ0_DANRE Computationally mapped isoform of tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like OS=Danio rerio OX=7955 GN=dus1l PE=1 SV=1 CANONICAL=B0S7L0-1" }, "locus": {} }, { "isoform_ac": "B0S7L0-1", "url": "https://www.uniprot.org/uniprotkb/B0S7L0/entry#B0S7L0-1", "sequence": { "sequence": "MCRIYRSLAVPQATAGSMTKPLGFEFWRRTLKGARFVVAPMVDQSELAWRLLSRRHGAELCYTPMLHAQVFVRDANYRRENLYSEVNQEDRPLITQFCANDPEVFIQAALLAQDYCDAIDLNLGCPQMIAKRGHYGVFLQDEWDLLEKMIKLANEKLSVPITCKIRVFPEIEKTVKYAKMLEKAGCQLLTVHGRTKDQKGALTGIASWKHIKAVREAVNIPVFANGNIQHLSDVHHCMEETGVQGVMSAEGNLHNPALFEGRSPPVWEMAEEYLDIVEKHSPCSLSFVRAHIFKLWHHTLQIHQDLREDLAKAKNVDGIVEVNRQLKQRCQEEMAKDESEWNQTGLPFPHWICQPYVRPPPKDPNTENGQKSQETKAVSVKRALEDSDGPNDAMSKNKQKKKARNPHKNFCPELKPKYIKCEQCGNPKGNKCVFNLCRGCCKRKAFKEVADCPGHGLKFKTKALRQCNSDTSGGGLTNGKASTQTVSTAVHDPLQA", "length": 496, "header": "tr|B0S7L0-1|B0S7L0_DANRE Isoform 1 of tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like OS=Danio rerio OX=7955 GN=dus1l PE=1 SV=1 CANONICAL=B0S7L0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0S7L0", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolutionary emergence of the rac3b/rfng/sgca regulatory cluster refined mechanisms for hindbrain boundaries formation.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2018", "authors": "Letelier Joaqu\u00edn, Terriente Javier, Belzunce Ivan, Voltes Adria, Undurraga Cristian Alberto, Polvillo Rocio, Devos Lucie, Tena Juan J, Maeso Ignacio, Retaux Sylvie, Gomez-Skarmeta Jos\u00e9 Luis, Mart\u00ednez-Morales Juan R, Pujades Cristina", "evidence": [ { "database": "UniProtKB", "id": "B0S7L0", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ], "reference": [ { "type": "PubMed", "id": "29610331", "url": "https://glygen.org/publication/PubMed/29610331" } ] } ], "pathway": [ { "id": "dre:322715", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:322715", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287ADL9-1", "protein_name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "gene_name": "DUS1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPKLQGFEFWSRTLGGARHVVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCEACPEDRPLIVQFCANDPEVFVQAALLAQDYCDAVDLNLGCPQMIAKRGHYGAFLQEEWDLLRRMILLAHEKLSVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPLSGAASWEHIKAVRKAVAIPVFANGNIQCLRDVERCLQDTGVQGVMSAEGHLHNPALFEGRSPAVWELAEEYLDLVRQHPCPLSYVRAHLFKLWHHTLQVHQQLREELAKVKTLEGIAAVSQELKLRCQEDISRQKEGEKPSGGLPFFHWICQPYFRPGPQEGSKENGGARSKRALEEEGSTEALSKNKQKKQLRNPHKTFDPSLKPKYAKCDQCGNPKGNRCVFNLCRGCCKKRAFRETADCPGHGLLFKTKLEKSLAWKGAQLRPQEPPQAGPAPLGGLPEAVGSALT", "length": 474 }, "evidence": [ { "id": "B0S7L0", "url": "https://omabrowser.org/oma/group/B0S7L0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1AID9-1", "protein_name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "gene_name": "DUS1L", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPKLRGEAFWRETLRGAHYVVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFLRDANYRRENLYGEACPEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQEEWDLLQRMILLANEKLSVPITCKIRVFPEIDKTVKYAQMLERAGCQDFVFQLLTVHGRTKEQKGPLAGVASWEHIQAVRKAVSIPVFANGNIQCLSDVEECIRKTGVHGVMSAEGNLHNPALFEGRNPLVWEMAEEYLEIVQKYPCPLSYVRAHLFKLWHHTLQVYQQLREELAKVKTLEGIVDVNRELKLRCQEEIANQKEGEKPKEGLPFFHWICQPYIRPGPKERCKENGTQGTEKGVRGKRSLEEEEDGNSELLSKNKQKKKLRNPNKSFDPSLKPKYAKCDQCGNPKGNKCVFNMCRGCCKKRAFKETADCPGHGLLFKTKYEKSLLWQNSQRAIPSPELSRKGDVDGEETAVLKEADDSAV", "length": 491 }, "evidence": [ { "id": "B0S7L0", "url": "https://omabrowser.org/oma/group/B0S7L0/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "G3N340-1", "protein_name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "gene_name": "DUS1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPKLEGFEFWSRTLGGARHVVAPMVDQSELAWRLLSRRHGAHLCYTPMLHAQVFVRDANYRKENLYCDVCPEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQEEWDLLQRMILLAHEKLSVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPLSGTASWEHIKAVRKAVTIPVFANGNIQCLRDVERCIQDTGVQGVMSAEGNLHNPALFEGRSPAVWELAEEYLDIVRQHPCPLSYVRAHLFKLWHHTLQVHQQLREELAKVKTLEGIAAVSQELKLRCQEDISRQKEGEKPSGGLPFFHWICQPYFRPGPKEGSKENGGARSKRALEEEEGTTDVLSKNKQKKKLRNPHKTFDPLLKPKYAKCDQCGNPKGNRCVFNLCRGCCKKRAFKETADCPGHGLLFKTKLERSLVWKGAQPRLQEPQQAGPGEPGGFPEVVGSALA", "length": 475 }, "evidence": [ { "id": "B0S7L0", "url": "https://omabrowser.org/oma/group/B0S7L0/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "P53759-1", "protein_name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]", "gene_name": "DUS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MTEPALSSANNALMQKLTGRQLFDKIGRPTRIVAPMVDQSELAWRILSRRYGATLAYTPMLHAKLFATSKKYREDNWSSLDGSSVDRPLVVQFCANDPEYLLAAAKLVEDKCDAVDLNLGCPQGIAKKGHYGSFLMEEWDLIHNLINTLHKNLKVPVTAKIRIFDDCEKSLNYAKMVLDAGAQFLTVHGRVREQKGQKTGLANWETIKYLRDNLPKETVFFANGNILYPEDISRCMEHIGADAVMSAEGNLYNPGVFNVGQTKNKEKIFPRVDKIIREYFQIVKECQESKASKTAMKSHFFKILRPFLPHHTDIRSTLATMNAKATWEEWEEQVVKPVEKVVQEIFEQPDIAIKDEITIGEKQSWGGSYRTVPYWRCQPYFRPVNGITGDKRVMQGLIDESVNKKRKADVPLESADKKKDVKA", "length": 423 }, "evidence": [ { "id": "HGNC:30086", "url": "https://alliancegenome.org/gene/HGNC:30086#orthology", "database": "AGR" }, { "id": "B0S7L0", "url": "https://omabrowser.org/oma/group/B0S7L0/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6P1R4-1", "protein_name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "gene_name": "DUS1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPKLQGFEFWSRTLRGARHVVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCEVCPEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQDEWDLLQRMILLAHEKLSVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPLSGAASWEHIKAVRKAVAIPVFANGNIQCLQDVERCLRDTGVQGVMSAEGNLHNPALFEGRSPAVWELAEEYLDIVREHPCPLSYVRAHLFKLWHHTLQVHQELREELAKVKTLEGIAAVSQELKLRCQEEISRQEGAKPTGDLPFHWICQPYIRPGPREGSKEKAGARSKRALEEEEGGTEVLSKNKQKKQLRNPHKTFDPSLKPKYAKCDQCGNPKGNRCVFSLCRGCCKKRASKETADCPGHGLLFKTKLEKSLAWKEAQPELQEPQPAAPGTPGGFSEVMGSALA", "length": 473 }, "evidence": [ { "id": "HGNC:30086", "url": "https://alliancegenome.org/gene/HGNC:30086#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-1435", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1435#orthology", "database": "AGR" }, { "id": "B0S7L0", "url": "https://omabrowser.org/oma/group/B0S7L0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C2P3-1", "protein_name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "gene_name": "Dus1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPKLQGFEFWSRTLGGARHVVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCDVCPEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGHYGAFLQEEWDLLQRMILLAHERLSVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPMAGTASWEHIKAVRKAVGIPVFANGNIQCLQDVERCIQDTGVQGVMSAEGNLHNPALFEGRSPAVWELAEEYLDIVRQHPCPLSYVRAHLFKLWHHTLQVHQQLREELAKVKTLEGVAAVSQALKLRCQEDMSRQQEGVRPADNLPAFHWICQPYIRPGPREGSKENSGGRSKRALEEEEGSMEGLSKNKLKKQLRNPHKTFDPSLKPKYAKCDQCGNPKGNRCVFNLCRGCCKKRAFRETADCPGHGLLFKTKLEKSLAWKGTQPGLQEAQQVRPVTPSGFSEVVGSALA", "length": 475 }, "evidence": [ { "id": "HGNC:30086", "url": "https://alliancegenome.org/gene/HGNC:30086#orthology", "database": "AGR" }, { "id": "B0S7L0", "url": "https://omabrowser.org/oma/group/B0S7L0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8K582-1", "protein_name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "gene_name": "Dus1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPKLQGFEFWSRALGGARHVVAPMVDQSELAWRLLSRRHGAQLCYTPMLHAQVFVRDANYRKENLYCDVCPEDRPLIVQFCANDPEVFVQAALLAQDYCDAIDLNLGCPQMIAKRGRYGAFLQEEWDLLQRMILLAHERLSVPVTCKIRVFPEIDKTVRYAQMLEKAGCQLLTVHGRTKEQKGPMAGTASWEHIKAVRKAVGIPVFANGNIRCLQDVERCIQDTGVQGVMSAEGNLHNPALFEGRSPAVWELADEYLDIVRQHPCPLSYVRAHLFKLWHHTLQVHQQLREELAKVKTLEGVAAVSQALKLRCQEDMARQQEGVRPADNLPAFHWICQPYIRPGPKEGSKENSSGRSKRALEEEEGSMEGLSKNKLKKQLRNPHKTFDPSLKPKYAKCDQCGNPKGNRCVFNLCRGCCKKRAFRETADCPGHDCFLRPN", "length": 438 }, "evidence": [ { "id": "HGNC:30086", "url": "https://alliancegenome.org/gene/HGNC:30086#orthology", "database": "AGR" }, { "id": "B0S7L0", "url": "https://omabrowser.org/oma/group/B0S7L0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9VPM1-1", "protein_name": "tRNA-dihydrouridine(16/17) synthase [NAD(P)(+)]-like", "gene_name": "Dus1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MVNDEDAAHQRPSKPTGYNFYRSSLGSPRYVVAPMVDQSELAWRMLCRRYGAELCYSPMYHANLFATDPKYRKDALQTCPEDRPLIIQFCGNDAQQILDAALLAQDHCDAVDINLGCPQAIAKRGHYGSFLQDEWELLTEIVSTLHAKLAVPVTCKIRIFEDLEKTIRYAKMLEAAGCQLLTVHGRTREQKGPLTGVANWNYIKNVRQHIKIPMLANGNILALDDVHRCLTETGVDGVMSAEGNLHNPAIFKGVSPPVWQMAHEYLELVQLHPCPSSFIRGHLFKLFHHIMNIRQNSELRQYLATANQLVQFQAVVQQVRAKYEPFHKGEVPYEPEQMAAGSEEDLPLSPWLCQPYIRASPESHRQKIAEKVREAEDPNRTKRQYFDKDGKEISRKRMKKLRRRQRRPNKTEAQIQHRHERRLEYCSECANPQGSKCEFQLCRVCCKDRCYNNDRDCPGHGIFIKSRRARAKLFEEHIAPQDHQKVTRTSDDDLTIAPTDAQEPL", "length": 505 }, "evidence": [ { "id": "HGNC:30086", "url": "https://alliancegenome.org/gene/HGNC:30086#orthology", "database": "AGR" }, { "id": "B0S7L0", "url": "https://omabrowser.org/oma/group/B0S7L0/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0S7L0", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B0S7L0", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "tRNA dihydrouridine synthase activity", "id": "GO:0017150", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0017150", "evidence": [ { "database": "UniProtKB", "id": "B0S7L0", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ], "pmid": "" }, { "name": "oxidoreductase activity", "id": "GO:0016491", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016491", "evidence": [ { "database": "UniProtKB", "id": "B0S7L0", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "tRNA processing", "id": "GO:0008033", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008033", "evidence": [ { "database": "UniProtKB", "id": "B0S7L0", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "53368", "name": "", "equation": "5,6-dihydrouridine(17) in tRNA + NADP(+) = uridine(17) in tRNA + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "B0S7L0-1" ], "evidence": [ { "id": "53368", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53368" } ] }, { "id": "53372", "name": "", "equation": "5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "B0S7L0-1" ], "evidence": [ { "id": "53372", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53372" } ] }, { "id": "53376", "name": "", "equation": "5,6-dihydrouridine(16) in tRNA + NADP(+) = uridine(16) in tRNA + NADPH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "B0S7L0-1" ], "evidence": [ { "id": "53376", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53376" } ] }, { "id": "53380", "name": "", "equation": "5,6-dihydrouridine(16) in tRNA + NAD(+) = uridine(16) in tRNA + NADH + H(+)", "summary": "", "cellular_location": "", "input_participant_list": [], "output_participant_list": [], "enzyme_list": [ "B0S7L0-1" ], "evidence": [ { "id": "53380", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/53380" } ] } ], "reaction_participants": [], "reaction_enzymes": [ { "uniprot_ac": "B0S7L0", "gene_name": "dus1l", "activity": [ { "ec_number": "1.3.1.88", "activity": "5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+).", "evidence": [ { "id": "B0S7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ] }, { "ec_number": "1.3.1.88", "activity": "", "evidence": [ { "id": "B0S7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0S7L0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0S7L0" }, { "id": "PF01207", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01207" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DUS-like FMN-binding", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 327, "start_aa": "Val", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.3.1.88", "ec_name": "5,6-dihydrouridine(17) in tRNA + NAD(+) = uridine(17) in tRNA + NADH + H(+).", "evidence": [ { "id": "1.3.1.88", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.3.1.88" }, { "id": "1.3.1.88", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.3.1.88" } ] } ], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 342, "end_pos": 344 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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}, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0UXZ0-1", "uniprot_ac": "B0UXZ0", "uniprot_id": "B0UXZ0_DANRE", "mass": { "chemical_mass": 18577.0, "monoisotopic_mass": 18577.0 }, "refseq": { "ac": "NP_001186923", "name": "cyclin-dependent kinase 4 inhibitor C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186923" }, "gene_names": [ { "name": "cdkn2c", "type": "recommended", "evidence": [ { "id": "B0UXZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0" } ] }, { "name": "cdkn2c", "type": "synonym", "evidence": [ { "id": "NP_001186923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186923" } ] }, { "name": "si:ch211-165l2.2", "type": "synonym", "evidence": [ { "id": "NP_001186923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186923" }, { "id": "B0UXZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0" } ] } ], "protein_names": [ { "name": "Cyclin-dependent kinase 4 inhibitor C", "type": "synonym", "evidence": [ { "id": "B0UXZ0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0/entry#names_and_taxonomy" } ] }, { "name": "cyclin-dependent kinase 4 inhibitor C", "type": "synonym", "evidence": [ { "id": "NP_001186923", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186923" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC091928.1, EH456215.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505376, SAMEA3505391 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001186923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186923" } ] }, { "annotation": "A functional analysis of dmrta2 in Danio rerio is reported; mutagenic analysis suggested that Dmrta2 might regulate the expression of cdkn2c during spermatogenesis. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001186923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186923" }, { "database": "PubMed", "id": "23175770", "url": "https://glygen.org/publication/PubMed/23175770" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0UXZ0", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cdkn2c", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-145", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-145", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000057610", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000057610", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "555797", "url": "https://www.ncbi.nlm.nih.gov/gene/555797", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036770", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036770", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050776", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050776", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:555797", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555797", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MAEPLGN", "url": "https://omabrowser.org/oma/group/MAEPLGN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0UXZ0", "url": "https://www.orthodb.org/?gene=B0UXZ0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24201", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24201", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24201:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24201:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00023", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00023", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13637", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13637", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186923", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0UXZ0", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0UXZ0-1", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-145", "url": "https://zfin.org/ZDB-GENE-081104-145", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAEDTALDRLSTAAAIGDLMEVEQTLQSNVNVNEKNKYGRTALQVMKLGCPSIAETLLQAGADPNVRDPILGLTVIHDAARDGYLDTLHVLAQNGADVNLLDNDGNLPLHLAAREGHLDVVQFLVTHCVTQPFLANAKGYTPRDLAFMHQKHRTVEWLESIASLQSSQRL", "length": 170, "header": "tr|B0UXZ0-1|B0UXZ0_DANRE Isoform 1 of Cyclin-dependent kinase 4 inhibitor C OS=Danio rerio OX=7955 GN=cdkn2c PE=4 SV=1 CANONICAL=B0UXZ0-1" }, "isoforms": [ { "isoform_ac": "B0UXZ0-1", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0/entry#B0UXZ0-1", "sequence": { "sequence": "MAEDTALDRLSTAAAIGDLMEVEQTLQSNVNVNEKNKYGRTALQVMKLGCPSIAETLLQAGADPNVRDPILGLTVIHDAARDGYLDTLHVLAQNGADVNLLDNDGNLPLHLAAREGHLDVVQFLVTHCVTQPFLANAKGYTPRDLAFMHQKHRTVEWLESIASLQSSQRL", "length": 170, "header": "tr|B0UXZ0-1|B0UXZ0_DANRE Isoform 1 of Cyclin-dependent kinase 4 inhibitor C OS=Danio rerio OX=7955 GN=cdkn2c PE=4 SV=1 CANONICAL=B0UXZ0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs.", "journal": "PLoS Genet.", "date": "2011", "authors": "Le Minh T N, Shyh-Chang Ng, Khaw Swea Ling, Chin Lingzi, Teh Cathleen, Tay Junliang, O'Day Elizabeth, Korzh Vladimir, Yang Henry, Lal Ashish, Lieberman Judy, Lodish Harvey F, Lim Bing", "evidence": [ { "database": "UniProtKB", "id": "B0UXZ0", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0" } ], "reference": [ { "type": "PubMed", "id": "21935352", "url": "https://glygen.org/publication/PubMed/21935352" } ] }, { "title": "Zebrafish dmrta2 regulates the expression of cdkn2c in spermatogenesis in the adult testis.", "journal": "Biol. Reprod.", "date": "2013", "authors": "Xu Shan, Xia Wei, Zohar Yonathan, Gui Jian-Fang", "evidence": [ { "database": "UniProtKB", "id": "B0UXZ0", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0" }, { "database": "RefSeq", "id": "NP_001186923", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186923" } ], "reference": [ { "type": "PubMed", "id": "23175770", "url": "https://glygen.org/publication/PubMed/23175770" } ] }, { "title": "Exome sequencing and functional analyses suggest that SIX6 is a gene involved in an altered proliferation-differentiation balance early in life and optic nerve degeneration at old age.", "journal": "Hum. Mol. Genet.", "date": "2014", "authors": "Iglesias Adriana I, Springelkamp Henri\u00ebt, van der Linde Herma, Severijnen Lies-Anne, Amin Najaf, Oostra Ben, Kockx Christel E M, van den Hout Mirjam C G N, van Ijcken Wilfred F J, Hofman Albert, Uitterlinden Andr\u00e9 G, Verdijk Rob M, Klaver Caroline C W, Willemsen Rob, van Duijn Cornelia M", "evidence": [ { "database": "UniProtKB", "id": "B0UXZ0", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0" } ], "reference": [ { "type": "PubMed", "id": "24150847", "url": "https://glygen.org/publication/PubMed/24150847" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0UXZ0", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Assignment of Functional Relevance to Genes at Type 2 Diabetes-Associated Loci Through Investigation of beta-Cell Mass Deficits.", "journal": "Mol. Endocrinol.", "date": "2016", "authors": "O'Hare Elizabeth A, Yerges-Armstrong Laura M, Perry James A, Shuldiner Alan R, Zaghloul Norann A", "evidence": [ { "database": "UniProtKB", "id": "B0UXZ0", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0" } ], "reference": [ { "type": "PubMed", "id": "26963759", "url": "https://glygen.org/publication/PubMed/26963759" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B0UXZ0", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Rag1 immunodeficiency-induced early aging and senescence in zebrafish are dependent on chronic inflammation and oxidative stress.", "journal": "Aging Cell", "date": "2019", "authors": "Novoa Beatriz, Pereiro Patricia, L\u00f3pez-Mu\u00f1oz Azucena, Varela M\u00f3nica, Forn-Cun\u00ed Gabriel, Anchelin Monique, Dios Sonia, Romero Alejandro, Martinez-L\u00f3pez Alicia, Medina-Gali Regla Mar\u00eda, Collado Manuel, Coll Julio, Estepa Amparo, Cayuela Mar\u00eda Luisa, Mulero Victoriano, Figueras Antonio", "evidence": [ { "database": "UniProtKB", "id": "B0UXZ0", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0" } ], "reference": [ { "type": "PubMed", "id": "31348603", "url": "https://glygen.org/publication/PubMed/31348603" } ] }, { "title": "Iroquois Homeobox 1 Acts as a True Tumor Suppressor in Multiple Organs by Regulating Cell Cycle Progression.", "journal": "Neoplasia", "date": "2019", "authors": "Jung In Hye, Jung Dawoon E, Chung Yong-Yoon, Kim Kyung-Sik, Park Seung Woo", "evidence": [ { "database": "UniProtKB", "id": "B0UXZ0", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0" } ], "reference": [ { "type": "PubMed", "id": "31450023", "url": "https://glygen.org/publication/PubMed/31450023" } ] }, { "title": "Pbx4 limits heart size and fosters arch artery formation by partitioning second heart field progenitors and restricting proliferation.", "journal": "Development", "date": "2020", "authors": "Holowiecki Andrew, Linstrum Kelsey, Ravisankar Padmapriyadarshini, Chetal Kashish, Salomonis Nathan, Waxman Joshua S", "evidence": [ { "database": "UniProtKB", "id": "B0UXZ0", "url": "https://www.uniprot.org/uniprotkb/B0UXZ0" } ], "reference": [ { "type": "PubMed", "id": "32094112", "url": "https://glygen.org/publication/PubMed/32094112" } ] } ], "pathway": [ { "id": "dre:555797", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555797", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1NLF9-1", "protein_name": "Cyclin dependent kinase 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"uniprot_canonical_ac": "G3GVX9-1", "protein_name": "Cyclin-dependent kinase 4 inhibitor C", "gene_name": "Cdkn2c", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPNLKDRTGFAVIHDAARAGFLDTVQALLEFQADVNIEDNEGNLPLHLAAKEGHLPVVEFLVKHTASNVGHRNHKGDTAFDLARFYGRNEVISLMEANGVGEATNPQ", "length": 168 }, "evidence": [ { "id": "B0UXZ0", "url": "https://omabrowser.org/oma/group/B0UXZ0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P42773-1", "protein_name": "Cyclin-dependent kinase 4 inhibitor C", "gene_name": "CDKN2C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPDLKDRTGFAVIHDAARAGFLDTLQTLLEFQADVNIEDNEGNLPLHLAAKEGHLRVVEFLVKHTASNVGHRNHKGDTACDLARLYGRNEVVSLMQANGAGGATNLQ", "length": 168 }, "evidence": [ { "id": "RGD:2325", "url": "https://alliancegenome.org/gene/RGD:2325#orthology", "database": "AGR" }, { "id": "MGI:105388", "url": "https://alliancegenome.org/gene/MGI:105388#orthology", "database": "AGR" }, { "id": "HGNC:1789", "url": "https://alliancegenome.org/gene/HGNC:1789#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-145", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-145#orthology", "database": "AGR" }, { "id": "B0UXZ0", "url": "https://omabrowser.org/oma/group/B0UXZ0/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q60772-1", "protein_name": "Cyclin-dependent kinase 4 inhibitor C", "gene_name": "Cdkn2c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPNLKDGTGFAVIHDAARAGFLDTVQALLEFQADVNIEDNEGNLPLHLAAKEGHLPVVEFLMKHTACNVGHRNHKGDTAFDLARFYGRNEVISLMEANGVGGATSLQ", "length": 168 }, "evidence": [ { "id": "RGD:2325", "url": "https://alliancegenome.org/gene/RGD:2325#orthology", "database": "AGR" }, { "id": "MGI:105388", "url": "https://alliancegenome.org/gene/MGI:105388#orthology", "database": "AGR" }, { "id": "HGNC:1789", "url": "https://alliancegenome.org/gene/HGNC:1789#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-145", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-145#orthology", "database": "AGR" }, { "id": "B0UXZ0", "url": "https://omabrowser.org/oma/group/B0UXZ0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8R5G4-1", "protein_name": "Cyclin-dependent kinase 4 inhibitor C", "gene_name": "Cdkn2c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAEPWGNELASAAARGDLEQLTSLLQNNVNVNAQNGFGRTALQVMKLGNPEIARRLLLRGANPNLKDRTGFAVIHDAARAGFLDTVQALLEFQADVNIEDNEGNLPLHLAAKEGHLPVVEFLMKHTACNVGHRNHKGDTAFDLARFYGRNEVISLMEANGVGGATSLQ", "length": 168 }, "evidence": [ { "id": "RGD:2325", "url": "https://alliancegenome.org/gene/RGD:2325#orthology", "database": "AGR" }, { "id": "MGI:105388", "url": "https://alliancegenome.org/gene/MGI:105388#orthology", "database": "AGR" }, { "id": "HGNC:1789", "url": "https://alliancegenome.org/gene/HGNC:1789#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-145", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-145#orthology", "database": "AGR" }, { "id": "B0UXZ0", "url": "https://omabrowser.org/oma/group/B0UXZ0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 9 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0UYC9-1", "uniprot_ac": "B0UYC9", "uniprot_id": "B0UYC9_DANRE", "mass": { "chemical_mass": 80106.0, "monoisotopic_mass": 80106.0 }, "refseq": { "ac": "XP_021329865", "name": "pleckstrin homology domain-containing family M member 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329865" }, "gene_names": [ { "name": "plekhm3", "type": "recommended", "evidence": [ { "id": "B0UYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UYC9" } ] }, { "name": "plekhm3", "type": "synonym", "evidence": [ { "id": "XP_021329865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329865" } ] } ], "protein_names": [ { "name": "Pleckstrin homology domain-containing family M member 3 isoform X1", "type": "synonym", "evidence": [ { "id": "B0UYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UYC9/entry#names_and_taxonomy" } ] }, { "name": "pleckstrin homology domain-containing family M member 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_021329865", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329865" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021329865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329865" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0UYC9", "url": "https://www.uniprot.org/uniprotkb/B0UYC9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "plekhm3", "url": "https://www.uniprot.org/uniprotkb/B0UYC9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070912-382", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-382", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "571507", "url": "https://www.ncbi.nlm.nih.gov/gene/571507", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001849", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001849", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011993", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011993", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR025258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR025258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036280", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036280", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051366", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051366", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:571507", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571507", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR12326", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12326", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12326:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12326:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00169", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00169", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13901", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13901", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_021329865", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021329865", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58GGM0", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGM0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GGM0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GGM0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0UYC9", "url": "https://www.uniprot.org/uniprotkb/B0UYC9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0UYC9-1", "url": "https://www.uniprot.org/uniprotkb/B0UYC9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070912-382", "url": "https://zfin.org/ZDB-GENE-070912-382", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEGLEVEDISPALEATEDYLHCLDDNHGDAQVHPPKLKEASTLDKLNSSGVWGLLTGKQSELSPGNMAWAEQTPFSVLGLRNGKRNRARSTNDLAAHAKETNSTTNTSSGGFKRGHNRSRSDVNNRTYTDNGMPAIDKNMFKNMALNDHRDAHKESSSYLVKQGTLEQREGPWGRWTACHVELTPCELRLYSLDSSGNQQLCAALSLSHCQGVSAPQPQDGRVLQAVFFNSTRVQLRAPCQWEALEWRRLLWERVLAARPTHSKAEPACANSPTPHEPDPDAAMVPAPRPLVRPTALPLFTQHCADVLKSGLLHQLTDLNNWRAFTFVLSRTDLQAFPTEGRGPVSEPVLRYQLASCLAVQRDDEDGGRSSRFQVVFPDDVLRLRAENEAKAQDWVEGLRIAVTAQRPQCESTEAPSGVLMRNKPTREKKHKEAQRAKRQSVTTSFLSILTCLAVEKGLTAQSFRCAGCQRPVGLSRGKAKVCAYSGWYYCTSCHQDNLFLIPARLLHNWDTNRHKVSKQAKEFLEFVYEEPLLDVQQLNPCLYEHCEPLAAVLKLRQQLQSLRAYLFSCRATVAEDLRRRIFPREYLLQHVHLYSLADLQQVIDGKLAPFLSKVIKFASSHVYSCSLCREKGFICELCHTGQVIYPFQENATKRCEGCGAVFHAECRMRAQPCPRCVRRELHKKPASFWKRHGPHDSPDDEVLDCFELDT", "length": 711, "header": "tr|B0UYC9-1|B0UYC9_DANRE Isoform 1 of Pleckstrin homology domain-containing family M member 3 isoform X1 OS=Danio rerio OX=7955 GN=plekhm3 PE=4 SV=1 CANONICAL=B0UYC9-1" }, "isoforms": [ { "isoform_ac": "A0AC58GGM0-1", "url": "https://www.uniprot.org/uniprotkb/B0UYC9/entry#A0AC58GGM0-1", "sequence": { "sequence": "MEGLEVEDISPALEATEDYLHCLDDNHGDAQVHPPKLKEASTLDKLNSSGVWGLLTGKQSELSPGNMAWAEQTPFSVLGLRNGKRNRARSTNDLAAHAKETNSTTNTSSGGFKRGHNRSRSDVNNRTYTDNGMPAIDKNMFKNMALNDHRDAHKESSSYLVKQGTLEQREGPWGRWTACHVELTPCELRLYSLDSSGNQQLCAALSLSHCQGVSAPQPQDGRVLQAVFFNSTRVQLRAPCQWEALEWRRLLWERVLAARPTHSKAEPACANSPTPHEPDPDAAMVPAPRPLVRPTALPLFTQHCADVLKSGLLHQLTDLNNWRAFTFVLSRTDLQAFPTEGRGPVSEPVLRYQLASCLAVQRDDEDGGRSSRFQVVFPDDVLRLRAENEAKAQDWVEGLRIAVTAQRPQCESTEAPSGVLMRNKPTREKKHKEAQRAKRQSVTTSFLSILTCLAVEKGLTAQSFRCAGCQRPVGLSRGKAKVCAYSGWYYCTSCHQDNLFLIPARLLHNWDTNRHKAYQ", "length": 519, "header": "tr|A0AC58GGM0-1|A0AC58GGM0_DANRE Computationally mapped isoform of Pleckstrin homology domain-containing family M member 3 isoform X2 OS=Danio rerio OX=7955 GN=plekhm3 PE=4 SV=1 CANONICAL=B0UYC9-1" }, "locus": {} }, { "isoform_ac": "B0UYC9-1", "url": "https://www.uniprot.org/uniprotkb/B0UYC9/entry#B0UYC9-1", "sequence": { "sequence": "MEGLEVEDISPALEATEDYLHCLDDNHGDAQVHPPKLKEASTLDKLNSSGVWGLLTGKQSELSPGNMAWAEQTPFSVLGLRNGKRNRARSTNDLAAHAKETNSTTNTSSGGFKRGHNRSRSDVNNRTYTDNGMPAIDKNMFKNMALNDHRDAHKESSSYLVKQGTLEQREGPWGRWTACHVELTPCELRLYSLDSSGNQQLCAALSLSHCQGVSAPQPQDGRVLQAVFFNSTRVQLRAPCQWEALEWRRLLWERVLAARPTHSKAEPACANSPTPHEPDPDAAMVPAPRPLVRPTALPLFTQHCADVLKSGLLHQLTDLNNWRAFTFVLSRTDLQAFPTEGRGPVSEPVLRYQLASCLAVQRDDEDGGRSSRFQVVFPDDVLRLRAENEAKAQDWVEGLRIAVTAQRPQCESTEAPSGVLMRNKPTREKKHKEAQRAKRQSVTTSFLSILTCLAVEKGLTAQSFRCAGCQRPVGLSRGKAKVCAYSGWYYCTSCHQDNLFLIPARLLHNWDTNRHKVSKQAKEFLEFVYEEPLLDVQQLNPCLYEHCEPLAAVLKLRQQLQSLRAYLFSCRATVAEDLRRRIFPREYLLQHVHLYSLADLQQVIDGKLAPFLSKVIKFASSHVYSCSLCREKGFICELCHTGQVIYPFQENATKRCEGCGAVFHAECRMRAQPCPRCVRRELHKKPASFWKRHGPHDSPDDEVLDCFELDT", "length": 711, "header": "tr|B0UYC9-1|B0UYC9_DANRE Isoform 1 of Pleckstrin homology domain-containing family M member 3 isoform X1 OS=Danio rerio OX=7955 GN=plekhm3 PE=4 SV=1 CANONICAL=B0UYC9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:571507", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571507", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9Q8H1-1", "protein_name": "Pleckstrin homology domain-containing family M member 1 isoform 1", "gene_name": "plekhm1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MLATQTPESGPDAKDVKQWIKGKIAHTLKALQKRYITTDTAVTSEDLEANLLCCALEAVFIHGIKSKFIRSDGGQVRKGGSRGALPQPVFWALLKTVTHRDVVQELERLSFINSDVGRCRAWVRLALNDGLLECYLTSLLRENSKMSTYYQPGALLLDPEDREVLLTLLQGLASLTFQLSYKSAVLNEWTNTPLVLAGLCPPTPADEQHLGPKRKESWDTVSQSSGGSGGSDWTPESLQRETRRDQIDGCDPSTPLTSSNLSLDTVSGSSHLSSSLSSDSLLQGQELRSPEKERWSCDSEINHNEQQKITATEESLMKEDIDVFIPAPDNLTDTHSVNEHTHIPDASLTSAQDTHHSHITEQSVENISVETKEETIEESEIIVKSTRLKAKNTVSETAEKEKKRESRDSSVDPPSVSALTETEETPDPKDTVLSEISAAPSPVETPQHAACRRTTMSVSRKISTDSLYSSCKSTSWISEEDFHKPEDLSISEAYAIIDVTPMNGQVSPVCEADELQPPPSVVHRRHNGLPNPFRGLLKLGQLERRSAVGMWWDYYCELSPFELRLYVNAEERVCNENLSLLRCEDIHLYSSTEGRFRLTFPNKRIYLRAPSKGEAEDWVDRITEAVNKLRPIMRDEQWEVLHTSSDQEVTSPAPSTPEHTISELPDPPQLDWTRHKDPEPDAIKEAVVYQSLEEKGWRCLVLSLSLEILRGFQVREDSKTPLFSLPIGSIRDVVPDVSLGSPAFFKVLTVRDTLTLRAESGEEARGWRSLIRGALDSYLETEDDGAGASAADGAQGGVVHKLVQHRLKGDGELLLHLSVVPIERGLDAQNYRCAGCSRQIGVSLGRGRLCEFSGQQFCDSCHQGDMSIIPSRMLHNWDLKTREVSRQAFKLLTQIEHEPLLNLAVLNPELFEHADIMAKVQNLRQRLRFLGDYVLLCRSGFSKQIQPRLQQRTYLLDNSDVYSVLDLQQIADGHYESYLQSLIQFGSKHVHNCDLCTQRGFICQICNAPDIIFPFQFDVTSRCNVCKTVFHSSCRAQCPVCPRCIRKQKYLERDLEES", "length": 1058 }, "evidence": [ { "id": "FB:FBgn0034694", "url": "https://alliancegenome.org/gene/FB:FBgn0034694#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0ABK0L3E5-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "Plekhm3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFSTFDSKLGKAVQQAEVYGVQEVPELVGHEVLGNITDNGALRSVASLGKGTMIWDHCKSRLLETKAQNVFPAKEQLMVQRGTAPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETTTFKPGHARSRSDVTHVDWRVVLSTMPLQQQQQQQQASLHGPHFPRPSFLLSSSNKVEDAQGNTEHKQTFPNILKKGYLEIRKNHDSYWQSCYAELSPYNLNFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNSQLQLKAESPWEALDWGQKLWEVVHAAVPNYMARQEEKANSPGLGHHVDCAQNHCLQKKSSGLLASPVLDSPKQYQNILKSGTLYRLTVQNNWKAFTFVLSKAYLMAFHPGKLDEDPLLSYNVDVCLAVQTDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANAARSSEQNLQVTLRNKPKDQLGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRPIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYLHAEPLATVARLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATAHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGSVFHSECKEKSVPCPRCVRRELQKKQKSFWRQLNVDESLEEACTMFELSYQNT", "length": 761 }, "evidence": [ { "id": "HGNC:34006", "url": "https://alliancegenome.org/gene/HGNC:34006#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-382", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-382#orthology", "database": "AGR" }, { "id": "RGD:1307151", "url": "https://alliancegenome.org/gene/RGD:1307151#orthology", "database": "AGR" }, { "id": "MGI:2443627", "url": "https://alliancegenome.org/gene/MGI:2443627#orthology", "database": "AGR" }, { "id": "FB:FBgn0034694", "url": "https://alliancegenome.org/gene/FB:FBgn0034694#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5PQS0-1", "protein_name": "Pleckstrin homology domain-containing family M member 1", "gene_name": "Plekhm1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSVENGLDPRAAIQVIKKKLVGSVKALQKQHVSLDTVVTSEDGDANTMCSALEAVFIHGLHAKYIRAEAGGKRKKHTHQKPLPQPVFWPLLKAVTHKHIISDLEHLVFINTDVGRCRAWLRLALNDGLMECYLKLLLQEPARLCEYYQPTALLRDAEEAEFLLSFLQGLTSLSFELSYKSAILNEWTLTPLSLSGLCPLSELDPLTVSGAELQRKESLDSISHSSGSEDIEVQHSGHKIRRDRKLTASSLSLDTASSSQLSCSLNSDSCLLQENGPKSPDHSEEPMSYDSDLGTANADDSDRSLQEVLSEFSKAQVNSAPSSGPSQESDTPMFQTPLSLHSLANSTHLLFEGSEEPFPAHTSSGTSSGHKHQPQESPDMQPLGTAQAGPAGSTSDQQPSSPVAGAADQGSEPWKALEYGRVGPKLVVSSPTSPKGKSWISEDDFCRPPKEHALKNTSDLCISPLQGTPELRTALHGPFSQGPRKSCSLGALDKACVSSLDYRNAQTAPSPAVTQDHKNFCVVHRRQMGLSNPFRGLMKLGTVARRGAMGIWKEFFCELSPLELRLYLSDEERTCVESCSLLRCEAVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVRPQQEEEWVNIQYPDQAEDSPEAPPDNLPPYSALLPEHAGAQGIQPNWTSAQVPEPDAIKESLLYLYADRTWIPYIFSLSLESLKCFRVRNNEKMLSDSHGVETIRDILPDTSLGGPAFFKIITAKAVLKLQAKNTEEAAHWRDLVRKVLASYLESVQEAVTLAGSLDENCQEVLKFATRENGFLLQYLVAIPTEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDFCHQDDASVIPARIIHNWDLTKRPVCRQALKFLAQIRAQPLINLQLVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELSKRLSHRNYLLESPHKFSVADLQQIAEGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICHHQDIIFPFEFDTTVRCAECRTVFHQSCQAVVRKGCPRCARRRKYQEQNTVS", "length": 1059 }, "evidence": [ { "id": "FB:FBgn0034694", "url": "https://alliancegenome.org/gene/FB:FBgn0034694#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6ZWE6-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "PLEKHM3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEALEVDDISPALEVTEEFFSTLDSNLEKAVQQAEVYGIQEVPELVGHEVLSNITDNGAMRNVTSLGKGGMIWDHCKSRLLETKAQNVFPAKEQFMVQRGTTPDNLSWMEQKEASTFNFFNICQRRRDRPRSVNDLLDETSTFKPGHARSRSDITQVDWRVVLKTTPLQQQQQQQPLLQGPHVTRPSFLLPSPNKIEDAQGNTEHKQTFPNILKKGYLEIRKDHDSYWQSCYAELSPYNLYFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNTQLQLKAESPWEALDWGQKLWEVVHAAVPGYMGRQNELTISPGLGHHDDYTQNHSFQKKTSGLLPPSPVLDSSKQYQNILKSGTLYRLTVQNNWKAFTFVLSRAYLMAFQPGKLDEDPLLSYNVDVCLAVQMDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKIAANVARSSEQNLQVTLRNKPKDQMGGHELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENAMLYHHAEPLAAVLRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATSHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWQRLNMDESLEEACTMFELSYQNT", "length": 761 }, "evidence": [ { "id": "HGNC:34006", "url": "https://alliancegenome.org/gene/HGNC:34006#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-382", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-382#orthology", "database": "AGR" }, { "id": "RGD:1307151", "url": "https://alliancegenome.org/gene/RGD:1307151#orthology", "database": "AGR" }, { "id": "MGI:2443627", "url": "https://alliancegenome.org/gene/MGI:2443627#orthology", "database": "AGR" }, { "id": "FB:FBgn0034694", "url": "https://alliancegenome.org/gene/FB:FBgn0034694#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TSI1-1", "protein_name": "Pleckstrin homology domain-containing family M member 1", "gene_name": "Plekhm1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSVENGLDPRAAIQVIKKKLVGSVKALQKQHVSLDTVVTSEDGDANTMCSALEAVFIHGLHAKHIRAEAGGKRKKHTHQKALPQPVFWPLLKAITHRHIVSDLEHLVFINTDVGRCRAWLRLALNDGLMECYLKLLLQEPARLCEYYQPTALLRDAEEAEFLLSFLQGLTSLSFELSYKSAILNEWTLTPLSLSGLCPLSELDPLTTSGAELQRKESLDSISHSSGSEDIEVQHSGHKIRRNRKLTASSLSLDTASSSQLSCSLNSDSCLLQENGPKSPDHSEEPMSYDSDLGMANTDDPDRSLQEVLSEFSKAQVNSAPSSGPNQEPDTPMFQTPLSLHSLATSTHLHFEGSEELFPAHKSSGTSSGGHKHQLLPQETPDEKQLGTAQAGPAQSTSDQQPSSPVGGAAGQGSGPWKALEYGRVGPKLVVSSPTSPKGKSWISEDDFCRPPQEPALKSAAGLCTSPVQDTPESRAALHGPFSQGPRKSCSLGALDKACVPSQACGNAQPAPAPAPAPAPAPAPAPGVTQDHKNFCVVHRRQMGLSNPFRGLMKLGTVARRGAMGIWKEFFCELSPLEFRLYLSDEERTCVESCSLLRCEAVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVRPQQEDEWVNIQYPDQAEDAPEAPPDSLPPYSTLLPEPAGAQGMQLDWTSAQVPEPDAIKESLLYLYADRTWVPYIFSLSLESLKCFRVRNNEKMLSDSHGVETIRDILPDTSLGGPAFFKIITAKAVLKLQAKNTEEATHWRDLVRKVLASYLESAEEAVTLGGSLDEKCQEVLKFATRENGFLLQYLVAIPTEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDFCHQDDASVIPARIIHNWDLTKRPVCRQALKFLAQIRAQPLINLQLVNASLYEHVERMHLIGRSREQLKLLGDYLGLCRSGALKELCKRLSHRNYLLESPHRFSVADLQQIAEGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICHHQDIIFPFEFDTTVRCAECRTVFHQSCQAVVRKGCPRCARRRKYQEQNVVS", "length": 1074 }, "evidence": [ { "id": "FB:FBgn0034694", "url": "https://alliancegenome.org/gene/FB:FBgn0034694#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8BM47-1", "protein_name": "Pleckstrin homology domain-containing family M member 3", "gene_name": "Plekhm3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEALEVDDISPALEVTEDFFSTFDSKLEKAVQQAEVYGIQEVPELVGHEVLGNIADNGALRSVASLGKGTMIWDHCKSRLLETKAQNVFPAKEQLMVQRGTAPDNLSWMAQKEASTFNFFNICQRRRDRPRSVNDLLDETTTFKPGHARSRSDVTHVDWRVVLSTMPLQQQQQQQQASLQGIHFPGPSFLLSSPSKVEDAQGNTEHKQTFPNILKKGYLEIRKNHDSYWQSCYAELSPYNLNFYSLDSSGNQNLYATYQLSHFQSISVLGNLEARMVDTVLYDNSQLQLKAESPWEALDWGQKLWEVVHAAVPNYMGRQGEMANSPGLIHHGDCAQNHCLQKKSSGLLASPVLDSPKQYQNILKSGTLYRLTVQNNWKAFTFVLSKAYLMAFHPGKLDEDPLLSYNVDVCLAVQIDNLDGCDSCFQVIFPQDVLRLRAETRQRAQEWMEALKTAANAARSSEQNLQVTLRNKPKDQLDGRELRKNKRQSVTTSFLSILTTLSLERGLTAQSFKCAGCQRSIGLSNGKAKVCNYSGWYYCSSCHVDDSFLIPARIVHNWDTSKYKVSKQAKEFLEYVYEEPLIDIQQENPMLYLHAEPLATVVRLRQRLKSLRAYLFSCRAAVAEDLRRRIFPREYLLQQIHLYSLADLQQVIEGKLAPFLGKVIKFATAHVYSCSLCSQKGFICEICNNGEILYPFEDISTSRCESCGAVFHSECKEKSVPCPRCVRRELQKKQKSFWRQLNVDESLEEACAMFELSYQST", "length": 761 }, "evidence": [ { "id": "HGNC:34006", "url": "https://alliancegenome.org/gene/HGNC:34006#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-382", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-382#orthology", "database": "AGR" }, { "id": "RGD:1307151", "url": "https://alliancegenome.org/gene/RGD:1307151#orthology", "database": "AGR" }, { "id": "MGI:2443627", "url": "https://alliancegenome.org/gene/MGI:2443627#orthology", "database": "AGR" }, { "id": "FB:FBgn0034694", "url": "https://alliancegenome.org/gene/FB:FBgn0034694#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9W293-1", "protein_name": "Pleckstrin homology and RUN domain containing M1", "gene_name": "Plekhm1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSLFRSLNHFSSKRENVVKEALINTLNENAREIEFEVKQKSLEVLGVCEQTSALCTTLEALFLHGLKDSFLSATFNVIAGDVERRPEPSFWAPCMVFMHKQVIEQVQGLSQITSETGQCRAWVRQSLNESVFSSYLNNMRKNGSALSQYYKRNALMRDSEGLETAAKIMESLEAYVQFDLPVNSSLLNHWPDYSLQLSDLWTPALKSCPISSGVDVASSLGSDIIAIPTPQPLQTNELFSESISNSPFGRNSNFGVPELSQRENLDLLIQKFDEMDVINEEQTGGDKAETNETAEQEAPSGSKTRSRKKSNRQMDSSSFADLDLEAPSLLPQGSNSLSNLMQTSWSGDLEATPTSPTEELTGSRFFQRSVSVSSSVSLRSPTTDRCSYNALLRKHESNRESGAGWSEIWEKFRASASNLNVAQPQRDTDPPISEDLSDLQSLDTNSEFELLTSEFDMVELQQMVAQLCQLAREPGLDAQGFLCKSCQHPLGIGYSNFQVCAFSGSYYCNSCMDVEMQLIPARIIYNWDFRKYSVSKRAATFLAEFRSHPFLDMQLLNPRIYFASDAMAELQSLRIRLNFIRAYLYTCAPSSIELLQNQFAGREYLYEHIHLYSIADLALIQRGVLCQQLQKAFKLGEAHVLKCRLCHLKGFICEICQSPRVLYPFHISTTFRCLACGAVFHAECLNEKQPCPKCERIRKREDQGLQEAVQCLKQKNEVA", "length": 720 }, "evidence": [ { "id": "HGNC:34006", "url": "https://alliancegenome.org/gene/HGNC:34006#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070912-382", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070912-382#orthology", "database": "AGR" }, { "id": "RGD:1307151", "url": "https://alliancegenome.org/gene/RGD:1307151#orthology", "database": "AGR" }, { "id": "MGI:2443627", "url": "https://alliancegenome.org/gene/MGI:2443627#orthology", "database": "AGR" }, { "id": "FB:FBgn0034694", "url": "https://alliancegenome.org/gene/FB:FBgn0034694#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y4G2-1", "protein_name": "Pleckstrin homology domain-containing family M member 1", "gene_name": "PLEKHM1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSVVENGLDPQAAIPVIKKKLVGSVKALQKQYVSLDTVVTSEDGDANTMCSALEAVFIHGLHAKHIRAEAGGKRKKSAHQKPLPQPVFWPLLKAVTHKHIISELEHLTFVNTDVGRCRAWLRLALNDGLMECYLKLLLQEQARLHEYYQPTALLRDAEEGEFLLSFLQGLTSLSFELSYKSAILNEWTLTPLALSGLCPLSELDPLSTSGAELQRKESLDSISHSSGSEDIEVHHSGHKIRRNQKLTASSLSLDTASSSQLSCSLNSDSCLLQENGSKSPDHCEEPMSCDSDLGTANAEDSDRSLQEVLLEFSKAQVNSVPTNGLSQETEIPTPQASLSLHGLNTSTYLHCEAPAEPLPAQAASGTQDGVHVQEPRPQAPSPLDLQQPVESTSGQQPSSTVSETAREVGQGNGLQKAQAHDGAGLKLVVSSPTSPKNKSWISEDDFYRPSREQPLESASDHPIASYRGTPGSRPGLHRHFSQEPRKNCSLGALDQACVPSPGRRQAQAAPSQGHKSFRVVHRRQMGLSNPFRGLMKLGTVERRGAMGIWKELFCELSPLEFRLYLSNEEHTCVENCSLLRCESVGPAHSDGRFELVFSGKKLALRASSQDEAEDWLDRVREALQKVRPQQEDEWVNVQYPDQPEEPPEAPQGCLSPSDLLSEPAALQGTQFDWSSAQVPEPDAIKESLLYLYMDRTWMPYIFSLSLEALKCFRIRNNEKMLSDSHGVETIRDILPDTSLGGPSFFKIITAKAVLKLQAGNAEEAALWRDLVRKVLASYLETAEEAVTLGGSLDENCQEVLKFATRENGFLLQYLVAIPMEKGLDSQGCFCAGCSRQIGFSFVRPKLCAFSGLYYCDICHQDDASVIPARIIHNWDLTKRPICRQALKFLTQIRAQPLINLQMVNASLYEHVERMHLIGRRREQLKLLGDYLGLCRSGALKELSKRLNHRNYLLESPHRFSVADLQQIADGVYEGFLKALIEFASQHVYHCDLCTQRGFICQICQHHDIIFPFEFDTTVRCAECKTVFHQSCQAVVKKGCPRCARRRKYQEQNIFA", "length": 1056 }, "evidence": [ { "id": "FB:FBgn0034694", "url": "https://alliancegenome.org/gene/FB:FBgn0034694#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B0UYC9", "url": "https://www.uniprot.org/uniprotkb/B0UYC9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 102, "end_pos": 104, "annotation": "n_glycosylation_sequon" }, { "start_pos": 106, "end_pos": 108, "annotation": "n_glycosylation_sequon" }, { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 125, "end_pos": 127, "annotation": "n_glycosylation_sequon" }, { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 47, "end_pos": 49, "annotation": "n_glycosylation_sequon" }, { "start_pos": 651, "end_pos": 653, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0UYC9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UYC9" }, { "id": "PS50003", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50003" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PH", "eco_id": "ECO_0000259", "start_pos": 306, "end_pos": 404, "start_aa": "Asp", "end_aa": "Thr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 102, "end_pos": 104 }, { "start_pos": 106, "end_pos": 108 }, { "start_pos": 117, "end_pos": 119 }, { "start_pos": 125, "end_pos": 127 }, { "start_pos": 230, "end_pos": 232 }, { "start_pos": 47, "end_pos": 49 }, { "start_pos": 651, "end_pos": 653 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0UYN4-1", "uniprot_ac": "B0UYN4", "uniprot_id": "B0UYN4_DANRE", "mass": { "chemical_mass": 24070.0, "monoisotopic_mass": 24070.0 }, "refseq": { "ac": "NP_001119927", "name": "uncharacterized protein LOC569993", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119927" }, "gene_names": [ { "name": "zgc:162944", "type": "synonym", "evidence": [ { "id": "NP_001119927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119927" }, { "id": "B0UYN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UYN4" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC569993", "type": "synonym", "evidence": [ { "id": "B0UYN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UYN4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC569993", "type": "synonym", "evidence": [ { "id": "NP_001119927", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001119927" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH435442.1, EH496850.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000009.1. 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The reference sequence was derived from JBMGRA010000009.1. 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"authors" ] } ] }, { "uniprot_canonical_ac": "B0UYU2-1", "uniprot_ac": "B0UYU2", "uniprot_id": "B0UYU2_DANRE", "mass": { "chemical_mass": 47141.0, "monoisotopic_mass": 47141.0 }, "refseq": { "ac": "NP_001314696", "name": "BEN domain-containing protein 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314696" }, "gene_names": [ { "name": "bend5", "type": "recommended", "evidence": [ { "id": "B0UYU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UYU2" } ] }, { "name": "bend5", "type": "synonym", "evidence": [ { "id": "NP_001314696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314696" } ] }, { "name": "si:dkeyp-21d8.1", "type": "synonym", "evidence": [ { "id": "NP_001314696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314696" }, { "id": "B0UYU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UYU2" } ] } ], "protein_names": [ { "name": "BEN domain-containing protein 5", "type": "recommended", "evidence": [ { "id": "B0UYU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UYU2/entry#names_and_taxonomy" } ] }, { "name": "BEN domain-containing protein 5", "type": "synonym", "evidence": [ { "id": "NP_001314696", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314696" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01006415.1, GDQH01005672.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505373, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On May 25, 2016 this sequence version replaced XP_005166976.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001314696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314696" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0UYU2", "url": "https://www.uniprot.org/uniprotkb/B0UYU2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "bend5", "url": "https://www.uniprot.org/uniprotkb/B0UYU2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-460", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-460", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000075624", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000075624", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "566161", "url": "https://www.ncbi.nlm.nih.gov/gene/566161", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR018379", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018379", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040391", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040391", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:566161", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566161", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HQKVYLV", "url": "https://omabrowser.org/oma/group/HQKVYLV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0UYU2", "url": "https://www.orthodb.org/?gene=B0UYU2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14628", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14628", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14628:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14628:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10523", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10523", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001314696", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314696", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0UYU2", "url": "https://www.uniprot.org/uniprotkb/B0UYU2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0UYU2-1", "url": "https://www.uniprot.org/uniprotkb/B0UYU2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-460", "url": "https://zfin.org/ZDB-GENE-081104-460", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MYAFVRFLEDDMCYALPVSDVKDFQPVHKRDFDDQKVYVVLRGAGQPAKAHILALAESIEEFEHSIMQKKMKIPKMSNRNTVENHFGEERMPLRHKKVQSQEHQRATSNSSKSLAAVVARLERNAVNSCTEGEELDRLTTEEEEEQDEAVVPRVLYEELVHSYRQQEEEMRRLQQELERTRRQLLQQAKKLKEYGSLLTEVKELRDFNRRLQDVLLMRLGSEPMHDNGTQTIKPEVVEPISEPQEACQEEANTSSTHSPSPRTVYTFNDGKVHLGGGIWVDEEKWHQLQRTQGDSKFTKNLAVMIWGTETLKNRSVTGVATKKKKDALPKPPLSPSKLKIVRECLYDRVSQETADSAEITQRLSKVNKYICEKIMDINKSIKNEERRESKLLIQQTVKMENFPYDGL", "length": 407, "header": "tr|B0UYU2-1|B0UYU2_DANRE Isoform 1 of BEN domain-containing protein 5 OS=Danio rerio OX=7955 GN=bend5 PE=4 SV=2 CANONICAL=B0UYU2-1" }, "isoforms": [ { "isoform_ac": "B0UYU2-1", "url": "https://www.uniprot.org/uniprotkb/B0UYU2/entry#B0UYU2-1", "sequence": { "sequence": "MYAFVRFLEDDMCYALPVSDVKDFQPVHKRDFDDQKVYVVLRGAGQPAKAHILALAESIEEFEHSIMQKKMKIPKMSNRNTVENHFGEERMPLRHKKVQSQEHQRATSNSSKSLAAVVARLERNAVNSCTEGEELDRLTTEEEEEQDEAVVPRVLYEELVHSYRQQEEEMRRLQQELERTRRQLLQQAKKLKEYGSLLTEVKELRDFNRRLQDVLLMRLGSEPMHDNGTQTIKPEVVEPISEPQEACQEEANTSSTHSPSPRTVYTFNDGKVHLGGGIWVDEEKWHQLQRTQGDSKFTKNLAVMIWGTETLKNRSVTGVATKKKKDALPKPPLSPSKLKIVRECLYDRVSQETADSAEITQRLSKVNKYICEKIMDINKSIKNEERRESKLLIQQTVKMENFPYDGL", "length": 407, "header": "tr|B0UYU2-1|B0UYU2_DANRE Isoform 1 of BEN domain-containing protein 5 OS=Danio rerio OX=7955 GN=bend5 PE=4 SV=2 CANONICAL=B0UYU2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:566161", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:566161", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQP2-1", "protein_name": "BEN domain-containing protein 5", "gene_name": "Bend5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MYAFVRFLEDNVCYALPVSCVRDFSPRSRLDFDNQKVYAVYRGPEELGVEPESPPRTPRDWGALLLHKAQILALAEDKSDLENSVMQKKIKIPKLSLSHVEDDGEAKDYGEEDLQLRHIKRPEGRKPSEAAHKSIEAVVARLERQNGLSLGHSTCPEEVFVEASAGTEDMDSLEDAVVPRALYEELLRNYQQQQEEMRHLQQELERTRRQLVQQAKKLKEYGALVSEMKELRDLNRRLQDVLLLRLGSGPAIDLEKVKSECLEPEPELRSTFSEEANTSSYYPAPAPVMDKYILDNGKVHLGSGIWVDEEKWHQLQVTQGDSKYTKNLAVMIWGTDVLKNRSVTGVATKKKKDAIPKPPLSPHKLSIVRECLYDRIAQETVDETEIAQRLSKVNKYICEKIMDINKSCKNEERREAKYNLQ", "length": 421 }, "evidence": [ { "id": "MGI:1914871", "url": "https://alliancegenome.org/gene/MGI:1914871#orthology", "database": "AGR" }, { "id": "HGNC:25668", "url": "https://alliancegenome.org/gene/HGNC:25668#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MFD0-1", "protein_name": "BEN domain-containing protein 5", "gene_name": "BEND5", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MYAFVRFLEDNVCYALPVSCVRDFSPRSRLDFDNQKVYAVYRGPEELGAGPESPPRAPRDWGALLLHKAQILALAEDKSDLENSVMQKKIKIPKLSLNLVEEDGEVKDYGEEDLQLRHIKRPEGRKPSEVAHKSIEAVVARLEKQNGLSLGPGTCPEEVFVEASAGAGDMDSLEDAGVPRALYEELLRNYQQQQEEMRHLQQELERTRRQLVQQAKKLKEYGALVAEMKELRDLNRRLQDVLLLRLGSGPAIDLEKVKSECLEPEPELRSTFSEEANTSSYYPAPAPVMDKYILDNGKVHLGSGIWVDEEKWHQLQVTQGDSKYTKNLAVMIWGTDVLKNRSVTGVATKKKKDAVPKPPLSPHKLSIVRECLYDRIAQETVDETEIAQRLSKVNKYICEKIMDINKSCKNEERREAKYNLQ", "length": 421 }, "evidence": [ { "id": "B0UYU2", "url": "https://omabrowser.org/oma/group/B0UYU2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q7L4P6-1", "protein_name": "BEN domain-containing protein 5", "gene_name": "BEND5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MYAFVRFLEDNVCYALPVSCVRDFSPRSRLDFDNQKVYAVYRGPEELGAGPESPPRAPRDWGALLLHKAQILALAEDKSDLENSVMQKKIKIPKLSLNHVEEDGEVKDYGEEDLQLRHIKRPEGRKPSEVAHKSIEAVVARLEKQNGLSLGHSTCPEEVFVEASPGTEDMDSLEDAVVPRALYEELLRNYQQQQEEMRHLQQELERTRRQLVQQAKKLKEYGALVSEMKELRDLNRRLQDVLLLRLGSGPAIDLEKVKSECLEPEPELRSTFSEEANTSSYYPAPAPVMDKYILDNGKVHLGSGIWVDEEKWHQLQVTQGDSKYTKNLAVMIWGTDVLKNRSVTGVATKKKKDAVPKPPLSPHKLSIVRECLYDRIAQETVDETEIAQRLSKVNKYICEKIMDINKSCKNEERREAKYNLQ", "length": 421 }, "evidence": [ { "id": "MGI:1914871", "url": "https://alliancegenome.org/gene/MGI:1914871#orthology", "database": "AGR" }, { "id": "HGNC:25668", "url": "https://alliancegenome.org/gene/HGNC:25668#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-460", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-460#orthology", "database": "AGR" }, { "id": "B0UYU2", "url": "https://omabrowser.org/oma/group/B0UYU2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C6D4-1", "protein_name": "BEN domain-containing protein 5", "gene_name": "Bend5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYAFVRFLEDNVCYALPVSCVRDFSPRSRLDFDNQKVYAVYRGPEELGAEPESPPRAPRDWGALLLHKAQILALAEDKSDLENSVMQKKIKIPKLSLSHVEDDGEVKDYGEEDLQLRHIKRPEGRKPSEAAHKSIEAVVARLERQNGLSLGHSTCPEEVFVEASPGTEDMDSLEDAVVPRALYEELLRNYQQQQEEMRHLQQELERTRRQLVQQAKKLKEYGALVSEMKELRDLNRRLQDVLLLRLGSGPAIDLEKVKSECLEPEPELRSTFSEEANTSSYYPAPAPVMDKYILDNGKVHLGSGIWVDEEKWHQLQVTQGDSKYTKNLAVMIWGTDVLKNRSVTGVATKKKKDAIPKPPLSPHKLSIVRECLYDRIAQETVDETEIAQRLSKVNKYICEKIMDINKSCKNEERREAKYNLQ", "length": 421 }, "evidence": [ { "id": "MGI:1914871", "url": "https://alliancegenome.org/gene/MGI:1914871#orthology", "database": "AGR" }, { "id": "HGNC:25668", "url": "https://alliancegenome.org/gene/HGNC:25668#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-460", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-460#orthology", "database": "AGR" }, { "id": "B0UYU2", "url": "https://omabrowser.org/oma/group/B0UYU2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "B0UYU2", "url": "https://www.uniprot.org/uniprotkb/B0UYU2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "B0UYU2", "url": "https://www.uniprot.org/uniprotkb/B0UYU2" } ], "pmid": "" }, { "name": "negative regulation of DNA-templated transcription", "id": "GO:0045892", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045892", "evidence": [ { "database": "UniProtKB", "id": "B0UYU2", "url": "https://www.uniprot.org/uniprotkb/B0UYU2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 109, "end_pos": 111, "annotation": "n_glycosylation_sequon" }, { "start_pos": 227, "end_pos": 229, "annotation": "n_glycosylation_sequon" }, { "start_pos": 252, "end_pos": 254, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 378, "end_pos": 380, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0UYU2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0UYU2" }, { "id": "PS51457", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51457" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "BEN", "eco_id": "ECO_0000259", "start_pos": 275, "end_pos": 381, "start_aa": "Gly", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 109, "end_pos": 111 }, { "start_pos": 227, "end_pos": 229 }, { "start_pos": 252, "end_pos": 254 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 378, "end_pos": 380 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { 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"recommended", "evidence": [ { "id": "B0V0W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V0W7" } ] }, { "name": "mplkip", "type": "synonym", "evidence": [ { "id": "NP_001189415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189415" } ] }, { "name": "si:ch211-202i17.3", "type": "synonym", "evidence": [ { "id": "NP_001189415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189415" }, { "id": "B0V0W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V0W7" } ] } ], "protein_names": [ { "name": "M-phase-specific PLK1-interacting protein", "type": "synonym", "evidence": [ { "id": "NP_001189415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189415" }, { "id": "B0V0W7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V0W7/entry#names_and_taxonomy" } ] }, { "name": "TTD non-photosensitive 1 protein-like", "type": "synonym", "evidence": [ { "id": "NP_001189415", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189415" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01025196.1, GDQQ01007145.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001189415", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189415" } ] } ], "disease": [ { "disease_id": "DOID:0050528", "recommended_name": { "id": "DOID:0050528", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050528", "name": "nonphotosensitive trichothiodystrophy 4", "description": "A nonphotosensitive trichothiodystrophy that is characterized by brittle hair, short stature, decreased fertility and cognitive impairment without photosensitivity has_material_basis_in mutations in the TTDN1 gene." }, "synonyms": [ { "id": "DOID:0050528", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050528", "name": "AMISH BRITTLE HAIR BRAIN SYNDROME", "description": "" }, { "id": "DOID:0050528", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050528", "name": "HAIR-BRAIN 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This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005167236", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167236" } ] } ], "disease": [ { "disease_id": "DOID:0050865", "recommended_name": { "id": "DOID:0050865", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050865", "name": "tongue squamous cell carcinoma", "description": "A head and neck squamous cell carcinoma that is located_in the tongue." }, "synonyms": [], "unlinked_id_list": [], "evidence": [ { "id": "0050865", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050865" } ] }, { "disease_id": "DOID:0080822", "recommended_name": { "id": "DOID:0080822", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080822", "name": "aspirin-induced respiratory disease", "description": "An intrinsic asthma that is characterized by severe and prolonged airway obstruction after the ingestion of aspirin or other non-steroidal anti-inflammatory drugs." }, "synonyms": [ { "id": "DOID:0080822", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080822", "name": "aspirin-sensitive asthma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0080822", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0080822" } ] }, { "disease_id": "DOID:0111087", "recommended_name": { "id": "DOID:0111087", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111087", "name": "Fanconi anemia complementation group C", "description": "A Fanconi anemia that has_material_basis_in homozygous or compound heterozygous mutation in the FANCC gene on chromosome 9q22." }, "synonyms": [ { "id": "DOID:0111087", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111087", "name": "FA3", "description": "" }, { "id": "DOID:0111087", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111087", "name": "FACC", "description": "" }, { "id": "DOID:0111087", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111087", "name": "FANCC", "description": "" }, { "id": "DOID:0111087", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111087", "name": "Fanconi pancytopenia type 3", "description": "" }, { "id": "MONDO:0009213", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009213", "name": "Fanconi anemia complementation group C", "description": "Fanconi anemia caused by mutations of the FANCC gene. 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It is a result of a genetic defect in a cluster of proteins responsible for DNA repair." }, "synonyms": [ { "id": "DOID:13636", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13636", "name": "Fanconi anaemia", "description": "" }, { "id": "DOID:13636", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13636", "name": "Fanconi pancytopenia", "description": "" }, { "id": "DOID:13636", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13636", "name": "Fanconi panmyelopathy", "description": "" }, { "id": "DOID:13636", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13636", "name": "Fanconi's anaemia", "description": "" }, { "id": "DOID:13636", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13636", "name": "Fanconi's anemia", "description": "" }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "Fanconi anemia complementation group A", "description": "Fanconi anemia caused by mutations of the FANCA gene. FANCA gene mutations are the most common cause of Fanconi anemia. This gene provides instructions for making a protein that is involved in the Fanconi anemia (FA) pathway." }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "FANCA", "description": "" }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "FANCA Fanconi anaemia", "description": "" }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "FANCA Fanconi anemia", "description": "" }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "Fanconi Anemia, complementation group type a", "description": "" }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "Fanconi anaemia caused by mutation in FANCA", "description": "" }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "Fanconi anaemia complementation group type A", "description": "" }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "Fanconi anemia caused by mutation in FANCA", "description": "" }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "Fanconi anemia complementation group A", "description": "" }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "Fanconi anemia complementation group type A", "description": "" }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "Estren-Dameshek variant of Fanconi Anaemia", "description": "" }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "Fanconi Anaemia", "description": "" }, { "id": "MONDO:0009215", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009215", "name": "Fanconi anemia, complementation group A", "description": "" }, { "id": "MIM:227650", "resource": "MIM", "url": "https://www.omim.org/entry/227650", "name": "Fanconi anemia, complementation group A", "description": "Fanconi anemia, complementation group A" } ], "unlinked_id_list": [], "evidence": [ { "id": "13636", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13636" } ] }, { "disease_id": "DOID:1612", "recommended_name": { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "breast cancer", "description": "An organ system cancer that originates in the mammary gland." }, "synonyms": [ { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "breast tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "malignant neoplasm of breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "malignant tumor of the breast", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "mammary cancer", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "mammary tumor", "description": "" }, { "id": "DOID:1612", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1612", "name": "primary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "Breast carcinoma that has developed in relatives of patients with history of breast carcinoma." }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer susceptibility, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, early-onset, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, invasive ductal, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, lobular, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, male, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, protection against, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, somatic", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "breast cancer, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial breast carcinoma", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "familial cancer of the breast", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast cancer", "description": "" }, { "id": "MONDO:0016419", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0016419", "name": "hereditary breast carcinoma", "description": "" }, { "id": "MIM:114480", "resource": "MIM", "url": "https://www.omim.org/entry/114480", "name": "Breast cancer", "description": "Breast cancer" } ], "unlinked_id_list": [ "DOID:3017", "DOID:0050938" ], "evidence": [ { "id": "1612", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1612" } ] }, { "disease_id": "DOID:1793", "recommended_name": { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "pancreatic cancer", "description": "An endocrine gland cancer located_in the pancreas." }, "synonyms": [ { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "Ca body of pancreas", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "Ca head of pancreas", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "Ca tail of pancreas", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "malignant neoplasm of body of pancreas", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "malignant neoplasm of head of pancreas", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "malignant neoplasm of tail of pancreas", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "pancreas neoplasm", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "pancreatic neoplasm", "description": "" }, { "id": "DOID:1793", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:1793", "name": "pancreatic tumor", "description": "" } ], "unlinked_id_list": [ "DOID:1795" ], "evidence": [ { "id": "1793", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:1793" } ] }, { "disease_id": "DOID:9119", "recommended_name": { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloid leukemia", "description": "A myeloid leukemia that is characterized by the rapid growth of abnormal white blood cells that accumulate in the bone marrow and interfere with the production of normal blood cells." }, "synonyms": [ { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "AML - acute Myeloid Leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "Leukemia, Myelocytic, acute", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloblastic leukaemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloblastic leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myelogenous leukaemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myelogenous leukemia", "description": "" }, { "id": "DOID:9119", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:9119", "name": "acute myeloid leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia", "description": "Acute myeloid leukemia (AML) is a group of neoplasms arising from precursor cells committed to the myeloid cell-line differentiation. All of them are characterized by clonal expansion of myeloid blasts. AML manifests by fever, pallor, anemia, hemorrhages and recurrent infections." }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML - acute myeloid leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "AML - acute myeloid leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "ANLL", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute Nonlymphocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute Nonlymphocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute granulocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute granulocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloblastic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelogenous leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myelogenous leukemias", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukaemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute myeloid leukemia, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute nonlymphocytic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute nonlymphocytic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "hematopoeitic - acute Myleogenous leukaemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "hematopoeitic - acute Myleogenous leukemia (AML)", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, reduced survival in, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid, susceptibility to, autosomal dominant, somatic mutation", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, myelocytic, acute", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "myeloid leukemia, acute", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "myeloid leukemia, acute, M4/M4Eo subtype, somatic", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute non lymphoblastic leukaemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "acute non lymphoblastic leukemia", "description": "" }, { "id": "MONDO:0018874", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0018874", "name": "leukemia, acute myeloid", "description": "" }, { "id": "MIM:601626", "resource": "MIM", "url": "https://www.omim.org/entry/601626", "name": "Leukemia, acute myelogenous", "description": "Leukemia, acute myelogenous" } ], "unlinked_id_list": [], "evidence": [ { "id": "9119", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:9119" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0V1A9", "url": "https://www.uniprot.org/uniprotkb/B0V1A9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fancc", "url": "https://www.uniprot.org/uniprotkb/B0V1A9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060510-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060510-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000055232", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000055232", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "692127", "url": "https://www.ncbi.nlm.nih.gov/gene/692127", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000686", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000686", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "RWHHRAS", "url": "https://omabrowser.org/oma/group/RWHHRAS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0V1A8", "url": "https://www.orthodb.org/?gene=B0V1A8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "B0V1A9", "url": "https://www.orthodb.org/?gene=B0V1A9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16798", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16798", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16798:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16798:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF02106", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF02106", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-6783310", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6783310", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-9833482", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9833482", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_005167236", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005167236", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0V1A8", "url": "https://www.uniprot.org/uniprotkb/B0V1A8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0V1A8-1", "url": "https://www.uniprot.org/uniprotkb/B0V1A8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0V1A9", "url": "https://www.uniprot.org/uniprotkb/B0V1A9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0V1A9-1", "url": "https://www.uniprot.org/uniprotkb/B0V1A9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060510-2", "url": "https://zfin.org/ZDB-GENE-060510-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAGVSETNVQFWMNKAVNWGEASSCSALLDTSRHLGPLRNFLQQILQGLQQMNSTSEAMKTFPFVGQFLGRLCWNSCVTADERSQKLLLRCLSCLYSAEPLNAVERKANMWIKNMLCHLISEEEGSVAHATVKHAGSTPMRYHTEALQKVVSLMVEEVSKSCDCLPNASARCSNSNIHTMSTACIALVTCTQMAPLIGALLKHSESCGSSCLNQEFINEVGEAFISKRLVLEDEAVISLWCQSALSLEGAAVSLLESVLSDHQLTTQSLDKHVNDSLLPQASARHCHIFLTVSEIYRNVLTEIDENLAIRTLIQVFTVCFLQRLTGQNSQDRLPLRAFFPNVMPSLLSPLLTAPSEVPREAWLDHLSWITSLLQSVTENEEEDVRAYQPMFEAWFLLVRCGYWVDTAVELLVLAASGNTEALLWLLTFFHHPTNRGHQRSQQTAVAREAWTHLRMLFLNHPPPPRHLSAVKELLSSSSISANLVLHLFSNFAVFSHGPVSIITEISDKVLTETAVRRRALWILASIRCRLNSASSRDDRVHSRLRTLQDTLLQT", "length": 554, "header": "tr|B0V1A9-1|B0V1A9_DANRE Isoform 1 of Fanconi anemia group C protein isoform X1 OS=Danio rerio OX=7955 GN=fancc PE=4 SV=1 CANONICAL=B0V1A9-1" }, "isoforms": [ { "isoform_ac": "B0V1A8-1", "url": "https://www.uniprot.org/uniprotkb/B0V1A9/entry#B0V1A8-1", "sequence": { "sequence": "MAGVSETNVQFWMNKAVNWGEASSCSALLDTSRHLGPLRNFLQQILQGLQQMNSTSEAMKTFPFVGQFLGRLCWNSCVTADERSQKLLLRCLSCLYSAEPLNAVERKANMWIKVVSLMVEEVSKSCDCLPNASARCSNSNIHTMSTACIALVTCTQMAPLIGALLKHSESCGSSCLNQEFINEVGEAFISKRLVLEDEAVISLWCQSALSLEGAAVSLLESVLSDHQLTTQSLDKHVNDSLLPQASARHCHIFLTVSEIYRNVLTEIDENLAIRTLIQVFTVCFLQRLTGQNSQDRLPLRAFFPNVMPSLLSPLLTAPSEVPREAWLDHLSWITSLLQSVTENEEEDVRAYQPMFEAWFLLVRCGYWVDTAVELLVLAASGNTEALLWLLTFFHHPTNRGHQRSQQTAVAREAWTHLRMLFLNHPPPPRHLSAVKELLSSSSISANLVLHLFSNFAVFSHGPVSIITEISDKVLTETAVRRRALWILASIRCRLNSASSRDDRVHSRLRTLQDTLLQT", "length": 518, "header": "tr|B0V1A8-1|B0V1A9_DANRE Computationally mapped isoform of Fanconi anemia group C protein isoform X1 OS=Danio rerio OX=7955 GN=fancc PE=4 SV=1 CANONICAL=B0V1A9-1" }, "locus": {} }, { "isoform_ac": "B0V1A9-1", "url": "https://www.uniprot.org/uniprotkb/B0V1A9/entry#B0V1A9-1", "sequence": { "sequence": "MAGVSETNVQFWMNKAVNWGEASSCSALLDTSRHLGPLRNFLQQILQGLQQMNSTSEAMKTFPFVGQFLGRLCWNSCVTADERSQKLLLRCLSCLYSAEPLNAVERKANMWIKNMLCHLISEEEGSVAHATVKHAGSTPMRYHTEALQKVVSLMVEEVSKSCDCLPNASARCSNSNIHTMSTACIALVTCTQMAPLIGALLKHSESCGSSCLNQEFINEVGEAFISKRLVLEDEAVISLWCQSALSLEGAAVSLLESVLSDHQLTTQSLDKHVNDSLLPQASARHCHIFLTVSEIYRNVLTEIDENLAIRTLIQVFTVCFLQRLTGQNSQDRLPLRAFFPNVMPSLLSPLLTAPSEVPREAWLDHLSWITSLLQSVTENEEEDVRAYQPMFEAWFLLVRCGYWVDTAVELLVLAASGNTEALLWLLTFFHHPTNRGHQRSQQTAVAREAWTHLRMLFLNHPPPPRHLSAVKELLSSSSISANLVLHLFSNFAVFSHGPVSIITEISDKVLTETAVRRRALWILASIRCRLNSASSRDDRVHSRLRTLQDTLLQT", "length": 554, "header": "tr|B0V1A9-1|B0V1A9_DANRE Isoform 1 of Fanconi anemia group C protein isoform X1 OS=Danio rerio OX=7955 GN=fancc PE=4 SV=1 CANONICAL=B0V1A9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "R-DRE-6783310", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6783310", "resource": "Reactome", "description": "Fanconi Anemia Pathway" }, { "id": "R-DRE-9833482", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9833482", "resource": "Reactome", "description": "PKR-mediated signaling" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A4X1UZU2-1", "protein_name": "Fanconi anemia group C protein homolog", "gene_name": "FANCC", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAQDLVALSSDYQFWMQKLSVWDQASTLETQQDTCLHLPQFQEFLRQMYEVLKEMDSSAITERFPTIGQLLAKVCRNPFILAYDESQKILIWCLCCLINKDPRNSGESKLNSWTRGLLSCILSTFRFDIKEVGLFTRGLGYAPTAYYPGLLKNMVLSLVSELRENHLNGFNTQRRMAPERITSLSRVCVPLVTLPEFEPLVEALLTYHGHEPQEVLCPEFFDAVNEAFLLKKISLPASAILCLWLRHLPSLENTMLHLFEKLVFSERNFLRRIECFMKDLLLPEAACHPAVFRVVDEMFRYALLETDGAPEVLAALQVFTRCFVEALEKENKQLRFAFKTYFPYASPSLVVTLLQHPKDIPRGLWSQPLRRISEMLQEIVEGQTHGSYGGPFESWFLFVHFGEWADIAAEQLLMVEAEAEAPEALLWLLAFSGSPGAGRRQRSQTMAEVKAVLGRLTKLLRSPTLSARDLQAAAGGGRGGDPSPPACGQLTRRLLLNFLLWAPGGRAIAREVITLIAQTDAITHEVIGFLDQTLYRWDHLCVEAPRPRELARELLTELRGQA", "length": 562 }, "evidence": [ { "id": "B0V1A9", "url": "https://omabrowser.org/oma/group/B0V1A9/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Y574-1", "protein_name": "Fanconi anemia group C protein homolog", "gene_name": "FANCC", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MHCGMAQDTTVPKLNFKFWLDKAIEWGQATTLESQKDVCLHLPQLQEFLHQTYETLKHMNSIAAIQQFPLIGQLLGRLCWNPFVVGYDESQKTLMWCLCCLYSSEPQNPVELKANSWIRSLLCHLLSSSKWERIEAETSTFISALGYTSADYYCHLVENIVSSLVTELRENQFNELNIQERISVSRVNAVSLFCLPLITLPDLTPLLETLLLYHGGASKEILSSEFLEAVNDAVLKKKISLSESAIFSLWHRHLPSLESATLSLLDQLTSLQINSLEKVACVIKDSLLPQAASHPAIFRIVNEIFKNALLETDGAPEVMTIIQVFIQLFIQVQQNENKQHKFPLKAYFPHHHQPLVIALLRRPFELPSTHWLQHLKHISDTLKSIVEDTNVSSFADLYEIWFLVACFGEWLDIAAEQLMKAAVAPDALLWLLAFYYCPQNENQQRTQTMVESQAVYSRLMMLYNRTVLSFGDLQASVNNAADTEQCHTQCLITHLLTNFLLFSSGGHMIAQEFISHITETTDMSKEVCSLLIRTAYRIKHNGGENQRTVKLLNELLQKLAVEV", "length": 563 }, "evidence": [ { "id": "B0V1A9", "url": "https://omabrowser.org/oma/group/B0V1A9/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "O35870-1", "protein_name": "Fanconi anemia group C protein homolog", "gene_name": "Fancc", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAQEPADLASDYQFWLQKLSAWEQASSKETQRDTCLHLSRFQEFLRQMYELLKEMDSDAILERFPSIGQLLAKTCWNPLILAYDESQKIVIWCLCCLMNKAPRTSAESGRNSWIQGLLSHVLSAFRFDMKEVCLFTKSLGYESIDYYPSLLKNMVLSLVSELRGSHLNGLNTQSRMAPERMMSLSQVCVPLVTLPDIEPLVEALLTYHGHEPQEVLSAEFFEAVTEAFLSEKVVLPTSSVVSLWFRHLPSLEKATLHLFEKLFSSKRNCLRRMECCIKESLLPQAACQPAIFRIVDEMFRFVLLETDGAPAVLAALQIFTSCLVEALRKENKQLKFALKTYFPYSAPCLTAALSQQPEAIPQGHRLQPLLHISQLLREAVEDCTDGSHRNPFESWFLFVHFGGWVDLAVEELLLREEAEPPAGLLWLLVFYYSPQDRSQQREQSMVELKVLVNRLLKLLRSGPLSAMDLLEAAESPREDPRPVCGQLVRRLLLSLLFWTPEGHAIVWEAVTHMAHTDAVTHEIVGFLDQTLYRSHHLCVEASRKLARELLKDLQAQV", "length": 557 }, "evidence": [ { "id": "HGNC:3584", "url": "https://alliancegenome.org/gene/HGNC:3584#orthology", "database": "AGR" }, { "id": "MGI:95480", "url": "https://alliancegenome.org/gene/MGI:95480#orthology", "database": "AGR" }, { "id": "B0V1A9", "url": "https://omabrowser.org/oma/group/B0V1A9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P50652-1", "protein_name": "Fanconi anemia group C protein homolog", "gene_name": "Fancc", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAQESADLASDCQSWLQKLSAWEQASSEETQKDTCLHLSGFQEFLRQMYEILKEMDSDAILERFPTIGQLLAKACWNPLILAYDESQKIVIWCLCCLMNKEPRTSAESGLNSWIRGLLSHVLSAFRFDMKEVCLFTKSLGYESIDYYPSLLKNMVLSLVSELRESHLNGLSTQSRMAPERMMSLSEVCVPLVTLPDMEPLVEALLTYHGHEPQEVLAPEFFEAVNEAFLSEKIVLPTSSVVSLWFRHLPSLEKATLHLFEKLFSSKIICLRRMECCIRESFLPQAACQPAIFRIVDEMFRFVLLETDGAPEVLAALQVFTSCLVEALKKENKQLTFALRTYFPYGAPCLAAALSQHPEAIPQGHRLQPLLHISQLLREAVEDCTRGSPRNPFESWFLFVHFGGWVDLAVAELLLREEAEPPAGLLWLLVFYYSPQDGSQQREQSMVELKVLINRLLMLLRSGPLSATDLQEAAESPSGDPRPPVCGQLVRRLLLSLLLWTPEGHAIVWEAVTHGPTFEITGPGCCPRIWRSTRPQHRPRAHLCCTEMAHTDAVIHEIIGFLDQTLYRSQHLCVEASRKLARDLLKELQAQV", "length": 591 }, "evidence": [ { "id": "HGNC:3584", "url": "https://alliancegenome.org/gene/HGNC:3584#orthology", "database": "AGR" }, { "id": "MGI:95480", "url": "https://alliancegenome.org/gene/MGI:95480#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060510-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060510-2#orthology", "database": "AGR" }, { "id": "B0V1A9", "url": "https://omabrowser.org/oma/group/B0V1A9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q00597-1", "protein_name": "Fanconi anemia group C protein", "gene_name": "FANCC", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQDSVDLSCDYQFWMQKLSVWDQASTLETQQDTCLHVAQFQEFLRKMYEALKEMDSNTVIERFPTIGQLLAKACWNPFILAYDESQKILIWCLCCLINKEPQNSGQSKLNSWIQGVLSHILSALRFDKEVALFTQGLGYAPIDYYPGLLKNMVLSLASELRENHLNGFNTQRRMAPERVASLSRVCVPLITLTDVDPLVEALLICHGREPQEILQPEFFEAVNEAILLKKISLPMSAVVCLWLRHLPSLEKAMLHLFEKLISSERNCLRRIECFIKDSSLPQAACHPAIFRVVDEMFRCALLETDGALEIIATIQVFTQCFVEALEKASKQLRFALKTYFPYTSPSLAMVLLQDPQDIPRGHWLQTLKHISELLREAVEDQTHGSCGGPFESWFLFIHFGGWAEMVAEQLLMSAAEPPTALLWLLAFYYGPRDGRQQRAQTMVQVKAVLGHLLAMSRSSSLSAQDLQTVAGQGTDTDLRAPAQQLIRHLLLNFLLWAPGGHTIAWDVITLMAHTAEITHEIIGFLDQTLYRWNRLGIESPRSEKLARELLKELRTQV", "length": 558 }, "evidence": [ { "id": "HGNC:3584", "url": "https://alliancegenome.org/gene/HGNC:3584#orthology", "database": "AGR" }, { "id": "MGI:95480", "url": "https://alliancegenome.org/gene/MGI:95480#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060510-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060510-2#orthology", "database": "AGR" }, { "id": "B0V1A9", "url": "https://omabrowser.org/oma/group/B0V1A9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "Fanconi anaemia nuclear complex", "id": "GO:0043240", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043240", "evidence": [ { "database": "UniProtKB", "id": "B0V1A9", "url": "https://www.uniprot.org/uniprotkb/B0V1A9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "interstrand cross-link repair", "id": "GO:0036297", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0036297", "evidence": [ { "database": "UniProtKB", "id": "B0V1A9", "url": "https://www.uniprot.org/uniprotkb/B0V1A9" } ], "pmid": "" }, { "name": "cellular response to oxidative stress", "id": "GO:0034599", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0034599", "evidence": [ { "database": "UniProtKB", "id": "B0V1A9", "url": "https://www.uniprot.org/uniprotkb/B0V1A9" } ], "pmid": "" }, { "name": "nucleotide-excision repair", "id": "GO:0006289", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006289", "evidence": [ { "database": "UniProtKB", "id": "B0V1A9", "url": "https://www.uniprot.org/uniprotkb/B0V1A9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 167, "end_pos": 169, "annotation": "n_glycosylation_sequon" }, { "start_pos": 274, "end_pos": 276, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 167, "end_pos": 169 }, { "start_pos": 274, "end_pos": 276 }, { "start_pos": 53, "end_pos": 55 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0V1R4-1", "uniprot_ac": "B0V1R4", "uniprot_id": "B0V1R4_DANRE", "mass": { "chemical_mass": 16503.0, "monoisotopic_mass": 16503.0 }, "refseq": { "ac": "NP_001164502", "name": "uncharacterized protein LOC795984 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164502" }, "gene_names": [ { "name": "LOC795984", "type": "recommended", "evidence": [ { "id": "B0V1R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V1R4" } ] }, { "name": "LOC795984", "type": "synonym", "evidence": [ { "id": "NP_001164502", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164502" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC795984 precursor", "type": "synonym", "evidence": [ { "id": "B0V1R4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V1R4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC795984 precursor", "type": "synonym", "evidence": [ { "id": "NP_001164502", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164502" } ] } ], "function": [ { "annotation": "PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from CR932977.11.", "evidence": [ { "database": "RefSeq", "id": "NP_001164502", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164502" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0V1R4", "url": "https://www.uniprot.org/uniprotkb/B0V1R4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC795984", "url": "https://www.uniprot.org/uniprotkb/B0V1R4", "locus": {} } ], "crossref": [ { "id": "795984", "url": "https://www.ncbi.nlm.nih.gov/gene/795984", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:795984", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795984", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001164502", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001164502", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58IF29", "url": "https://www.uniprot.org/uniprotkb/A0AC58IF29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IF29-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IF29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0V1R4", "url": "https://www.uniprot.org/uniprotkb/B0V1R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0V1R4-1", "url": "https://www.uniprot.org/uniprotkb/B0V1R4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MVSLSSFLVLILLSSSLLLSASGGHGGHNRVSHGHGSHGHDSLDSHGHGGHGHFSHDSHGHGGHGHFSHHSHGHGGHGHFSHHSHGHGGHGHFSHHSHGPGGHGHVSHGSHGHGGHGHGSHGSHGHGGHGHGSRGSHGHGGHGHGSHGSHGHGGHRHGSHGRRD", "length": 164, "header": "tr|B0V1R4-1|B0V1R4_DANRE Isoform 1 of Uncharacterized protein LOC795984 precursor OS=Danio rerio OX=7955 GN=LOC795984 PE=4 SV=1 CANONICAL=B0V1R4-1" }, "isoforms": [ { "isoform_ac": "A0AC58IF29-1", "url": "https://www.uniprot.org/uniprotkb/B0V1R4/entry#A0AC58IF29-1", "sequence": { "sequence": "MAVMDMIVSILMVMVVMAILVTILMVMVVMDILVTILMVMVVMDILVTILMVMVVMDILVTILMVLVVTDMLVTVLMVMEVTDMVVTVLMVMEVTDMVVAVLMVMEVTDMVVMVLMVMEVTDMVVMVLMDLVVSAVGTDLLGSGLFASFSTLEITFNKCFIQ", "length": 162, "header": "tr|A0AC58IF29-1|A0AC58IF29_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=LOC795984 PE=4 SV=1 CANONICAL=B0V1R4-1" }, "locus": {} }, { "isoform_ac": "B0V1R4-1", "url": "https://www.uniprot.org/uniprotkb/B0V1R4/entry#B0V1R4-1", "sequence": { "sequence": "MVSLSSFLVLILLSSSLLLSASGGHGGHNRVSHGHGSHGHDSLDSHGHGGHGHFSHDSHGHGGHGHFSHHSHGHGGHGHFSHHSHGHGGHGHFSHHSHGPGGHGHVSHGSHGHGGHGHGSHGSHGHGGHGHGSRGSHGHGGHGHGSHGSHGHGGHRHGSHGRRD", "length": 164, "header": "tr|B0V1R4-1|B0V1R4_DANRE Isoform 1 of Uncharacterized protein LOC795984 precursor OS=Danio rerio OX=7955 GN=LOC795984 PE=4 SV=1 CANONICAL=B0V1R4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:795984", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795984", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0V234-1", "uniprot_ac": "B0V234", "uniprot_id": "B0V234_DANRE", "mass": { "chemical_mass": 32441.0, "monoisotopic_mass": 32441.0 }, "refseq": { "ac": "NP_001006028", "name": "four and a half LIM domains protein 2b", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006028" }, "gene_names": [ { "name": "fhl2b", "type": "recommended", "evidence": [ { "id": "B0V234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ] }, { "name": "fhl2b", "type": "synonym", "evidence": [ { "id": "NP_001006028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006028" } ] }, { "name": "zgc:103466", "type": "synonym", "evidence": [ { "id": "NP_001006028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006028" }, { "id": "B0V234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ] } ], "protein_names": [ { "name": "Four and a half LIM domains protein 2b", "type": "synonym", "evidence": [ { "id": "B0V234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V234/entry#names_and_taxonomy" } ] }, { "name": "four and a half LIM domains protein 2b", "type": "synonym", "evidence": [ { "id": "NP_001006028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006028" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588727.1930324.1, SRR32588724.2552204.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476818 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000006.1. On Jan 9, 2009 this sequence version replaced NP_001006028.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001006028", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006028" } ] }, { "annotation": "Fhl2b mediates extraocular muscle protection in zebrafish models of muscular dystrophies and its ectopic expression ameliorates affected body muscles. Publication Status: Online-Only", "evidence": [ { "database": "RefSeq", "id": "NP_001006028", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006028" }, { "database": "PubMed", "id": "38431640", "url": "https://glygen.org/publication/PubMed/38431640" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fhl2b", "url": "https://www.uniprot.org/uniprotkb/B0V234", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041010-121", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-121", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000003991", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000003991", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09431", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09431", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd09433", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09433", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "450007", "url": "https://www.ncbi.nlm.nih.gov/gene/450007", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:450007", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:450007", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YECKKTI", "url": "https://omabrowser.org/oma/group/YECKKTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0V234", "url": "https://www.orthodb.org/?gene=B0V234", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24205:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24205:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001006028", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006028", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0V234-1", "url": "https://www.uniprot.org/uniprotkb/B0V234-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041010-121", "url": "https://zfin.org/ZDB-GENE-041010-121", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAERYDCHYCKESLFGKKYVLRDENPYCVKCYESLYSNTCEECKKPIGCNSRDLSYKDRHWHDDCFHCFKCHRSLVDKPFSTKDEQLLCTECYSNEYSSKCFECKKTIMPGSRKMEHKGNSWHETCFTCQRCQQPIGTKSFIPKDNSNYCVPCYEKQFALQCVQCKKPITTGGVTYHDQPWHKDCFLCTGCKQQLSGQRFTSRDDFPYCLNCFCNLYAKKCAACTTPISGLGGSKYISFEERQWHNDCFNCKKCSVSLVGRGFLTERDDILCPECGKDI", "length": 279, "header": "tr|B0V234-1|B0V234_DANRE Isoform 1 of Four and a half LIM domains protein 2b OS=Danio rerio OX=7955 GN=fhl2b PE=4 SV=1 CANONICAL=B0V234-1" }, "isoforms": [ { "isoform_ac": "B0V234-1", "url": "https://www.uniprot.org/uniprotkb/B0V234/entry#B0V234-1", "sequence": { "sequence": "MAERYDCHYCKESLFGKKYVLRDENPYCVKCYESLYSNTCEECKKPIGCNSRDLSYKDRHWHDDCFHCFKCHRSLVDKPFSTKDEQLLCTECYSNEYSSKCFECKKTIMPGSRKMEHKGNSWHETCFTCQRCQQPIGTKSFIPKDNSNYCVPCYEKQFALQCVQCKKPITTGGVTYHDQPWHKDCFLCTGCKQQLSGQRFTSRDDFPYCLNCFCNLYAKKCAACTTPISGLGGSKYISFEERQWHNDCFNCKKCSVSLVGRGFLTERDDILCPECGKDI", "length": 279, "header": "tr|B0V234-1|B0V234_DANRE Isoform 1 of Four and a half LIM domains protein 2b OS=Danio rerio OX=7955 GN=fhl2b PE=4 SV=1 CANONICAL=B0V234-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Four-and-a-half LIM domains protein 2 (FHL2) is associated with the development of craniofacial musculature in the teleost fish Sparus aurata.", "journal": "Cell. Mol. Life Sci.", "date": "2012", "authors": "Rafael Marta S, Laiz\u00e9 Vincent, Bensimon-Brito Anabela, Leite Ricardo B, Sch\u00fcle Roland, Cancela M Leonor", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "reference": [ { "type": "PubMed", "id": "21739231", "url": "https://glygen.org/publication/PubMed/21739231" } ] }, { "title": "Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment.", "journal": "Nat. Commun.", "date": "2013", "authors": "Baraban Scott C, Dinday Matthew T, Hortopan Gabriela A", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "reference": [ { "type": "PubMed", "id": "24002024", "url": "https://glygen.org/publication/PubMed/24002024" } ] }, { "title": "The evolution of cichlid fish egg-spots is linked with a cis-regulatory change.", "journal": "Nat. Commun.", "date": "2014", "authors": "Santos M Em\u00edlia, Braasch Ingo, Boileau Nicolas, Meyer Britta S, Sauteur Lo\u00efc, B\u00f6hne Astrid, Belting Heinz-Georg, Affolter Markus, Salzburger Walter", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "reference": [ { "type": "PubMed", "id": "25296686", "url": "https://glygen.org/publication/PubMed/25296686" } ] }, { "title": "Cardiac transcriptome and dilated cardiomyopathy genes in zebrafish.", "journal": "Circ. Cardiovasc. Genet.", "date": "2015", "authors": "Shih Yu-Huan, Zhang Yuji, Ding Yonghe, Ross Christian A, Li Hu, Olson Timothy M, Xu Xiaolei", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "reference": [ { "type": "PubMed", "id": "25583992", "url": "https://glygen.org/publication/PubMed/25583992" } ] }, { "title": "Pou3f transcription factor expression during embryonic development highlights distinct pou3f3 and pou3f4 localization in the Xenopus laevis kidney.", "journal": "Int. J. Dev. Biol.", "date": "2018", "authors": "Cosse-Etchepare Camille, Gervi Isabelle, Buisson Isabelle, Formery Laurent, Schubert Michael, Riou Jean-Fran\u00e7ois, Umbhauer Muriel, Le Bouffant Ronan", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "reference": [ { "type": "PubMed", "id": "29877572", "url": "https://glygen.org/publication/PubMed/29877572" } ] }, { "title": "Warfarin-exposed zebrafish embryos resembles human warfarin embryopathy in a dose and developmental-time dependent manner - From molecular mechanisms to environmental concerns.", "journal": "Ecotoxicol. Environ. Saf.", "date": "2019", "authors": "Granadeiro Luis, Dirks Ron P, Ortiz-Delgado Juan B, Gavaia Paulo J, Sarasquete Carmen, Laiz\u00e9 Vincent, Cancela M Leonor, Fern\u00e1ndez Ignacio", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "reference": [ { "type": "PubMed", "id": "31238190", "url": "https://glygen.org/publication/PubMed/31238190" } ] }, { "title": "Understanding the complexity of epimorphic regeneration in zebrafish caudal fin tissue: A transcriptomic and proteomic approach.", "journal": "Genomics", "date": "2022", "authors": "Banu Sarena, Gaur Namami, Nair Sowmya, Ravikrishnan Tanuja, Khan Shahida, Mani Sandhya, Bharathi Swarna, Mandal Komal, Kuram Naga Anusha, Vuppaladadium Sowmya, Ravi Rowmika, Murthy Ch Lakshmi N, Quoseena Mir, Babu Nukala Sarath, Idris Mohammed M", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "reference": [ { "type": "PubMed", "id": "35134499", "url": "https://glygen.org/publication/PubMed/35134499" } ] }, { "title": "fhl2b mediates extraocular muscle protection in zebrafish models of muscular dystrophies and its ectopic expression ameliorates affected body muscles.", "journal": "Nat. Commun.", "date": "2024", "authors": "Dennhag Nils, Kahsay Abraha, Nissen Itzel, Nord Hanna, Chermenina Maria, Liu Jiao, Arner Anders, Liu Jing-Xia, Backman Ludvig J, Remeseiro Silvia, von Hofsten Jonas, Pedrosa Domell\u00f6f Fatima", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" }, { "database": "RefSeq", "id": "NP_001006028", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001006028" } ], "reference": [ { "type": "PubMed", "id": "38431640", "url": "https://glygen.org/publication/PubMed/38431640" } ] } ], "pathway": [ { "id": "dre:450007", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:450007", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "O35115-1", "protein_name": "Four and a half LIM domains protein 2", "gene_name": "Fhl2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTERFDCHHCNESLYGKKYILKEENPHCVACFEELYANTCEECGTPIGCDCKDLSYKDRHWHEGCFHCSRCGSSLVDKPFAAKEEQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFTCQRCQQPIGTKSFIPKENQNFCVPCYEKQYALQCVQCKKPITTGGVTYRDQPWHRECFVCTACKKQLSGQRFTARDEFPYCLTCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI", "length": 279 }, "evidence": [ { "id": "HGNC:3703", "url": "https://alliancegenome.org/gene/HGNC:3703#orthology", "database": "AGR" }, { "id": "MGI:1338762", "url": "https://alliancegenome.org/gene/MGI:1338762#orthology", "database": "AGR" }, { "id": "RGD:61963", "url": "https://alliancegenome.org/gene/RGD:61963#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-121", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-121#orthology", "database": "AGR" }, { "id": "FB:FBgn0085354", "url": "https://alliancegenome.org/gene/FB:FBgn0085354#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O70433-1", "protein_name": "Four and a half LIM domains protein 2", "gene_name": "Fhl2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTERFDCHHCNESLYGKKYILKEENPHCVACFEELYANTCEECGTPIGCDCKDLSYKDRHWHEGCFHCSRCGSSLVDKPFAAKEEQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFTCQRCQQPIGTKSFIPKENQNFCVPCYEKQYALQCVQCKKPITTGGVTYREQPWHKECFVCTACKKQLSGQRFTARDEFPYCLTCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI", "length": 279 }, "evidence": [ { "id": "HGNC:3703", "url": "https://alliancegenome.org/gene/HGNC:3703#orthology", "database": "AGR" }, { "id": "MGI:1338762", "url": "https://alliancegenome.org/gene/MGI:1338762#orthology", "database": "AGR" }, { "id": "RGD:61963", "url": "https://alliancegenome.org/gene/RGD:61963#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-121", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-121#orthology", "database": "AGR" }, { "id": "FB:FBgn0085354", "url": "https://alliancegenome.org/gene/FB:FBgn0085354#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q14192-1", "protein_name": "Four and a half LIM domains protein 2", "gene_name": "FHL2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTERFDCHHCNESLFGKKYILREESPYCVVCFETLFANTCEECGKPIGCDCKDLSYKDRHWHEACFHCSQCRNSLVDKPFAAKEDQLLCTDCYSNEYSSKCQECKKTIMPGTRKMEYKGSSWHETCFICHRCQQPIGTKSFIPKDNQNFCVPCYEKQHAMQCVQCKKPITTGGVTYREQPWHKECFVCTACRKQLSGQRFTARDDFAYCLNCFCDLYAKKCAGCTNPISGLGGTKYISFEERQWHNDCFNCKKCSLSLVGRGFLTERDDILCPDCGKDI", "length": 279 }, "evidence": [ { "id": "HGNC:3703", "url": "https://alliancegenome.org/gene/HGNC:3703#orthology", "database": "AGR" }, { "id": "MGI:1338762", "url": "https://alliancegenome.org/gene/MGI:1338762#orthology", "database": "AGR" }, { "id": "RGD:61963", "url": "https://alliancegenome.org/gene/RGD:61963#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-121", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-121#orthology", "database": "AGR" }, { "id": "FB:FBgn0085354", "url": "https://alliancegenome.org/gene/FB:FBgn0085354#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5TD97-1", "protein_name": "Four and a half LIM domains protein 5", "gene_name": "FHL5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MTTAHFYCQYCTASLLGKKYVLKDDSPYCVTCYDRVFSNYCEECKKPIESDSKDLCYKDRHWHEGCFKCTKCNHSLVEKPFAAKDERLLCTECYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCENCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFCDQLWHKECFLCSGCRKDLCEEQFMSRDDYPFCVDCYNHLYANKCVACSKPISGLTGAKFICFQDSQWHSECFNCGKCSVSLVGKGFLTQNKEIFCQKCGSGMDTDI", "length": 284 }, "evidence": [ { "id": "FB:FBgn0085354", "url": "https://alliancegenome.org/gene/FB:FBgn0085354#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6AXT1-1", "protein_name": "Four and a half LIM domains protein 5", "gene_name": "Fhl5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSTQFDCQYCTASLLGKKYVLKDDNLYCISCYDRIFSNYCEQCKEPIESDSKDLCYKNRHWHEGCFRCNKCHHSLVEKPFVAKDERLLCTDCYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCEHCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFRDQIWHKECFLCSGCRKELYEEAFMSKDDFPFCLDCYNHLYAKKCAACTKPITGLRGAKFICFQDRQWHSECFNCGKCSVSLVGEGFLTQNMEILCRKCGSGADTDM", "length": 284 }, "evidence": [ { "id": "FB:FBgn0085354", "url": "https://alliancegenome.org/gene/FB:FBgn0085354#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8MLQ2-1", "protein_name": "LIM zinc-binding domain-containing protein", "gene_name": "CG17263", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSASICCRCNEKIWPRAVCSLGKTYHPHHFTCKECGLVVDPKLFFAVDDDVVCSECYLDKHAARCSACRTPILERGVAAAERKWHEKCFRCVSCSKSLVSASFFEVNGYLFCKAHFRELFSSRCAGCEKPIDRRAVVALSTKWHAKCFKCHHCRKRISAREFWIENGQPICAACQTVVPSPRNLSAQ", "length": 187 }, "evidence": [ { "id": "HGNC:3703", "url": "https://alliancegenome.org/gene/HGNC:3703#orthology", "database": "AGR" }, { "id": "MGI:1338762", "url": "https://alliancegenome.org/gene/MGI:1338762#orthology", "database": "AGR" }, { "id": "RGD:61963", "url": "https://alliancegenome.org/gene/RGD:61963#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VXC1-1", "protein_name": "LIM zinc-binding domain-containing protein", "gene_name": "Dmel\\CG34325", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSEQPSICHKCNEVIQLRIITALGKTWHPEHFVCKDCQCPITEASFNINDGQPVCSACFVSNYSGICHGCKRPILERTIKAMGETWHEECFLCRGPCMQQLAGSSFYEHDGLPYCRTDFEHMFAARCGNCKAPITENAIVALDAKWHRECFKCKKCKTPITASSFVVEDNQPLCKACSD", "length": 179 }, "evidence": [ { "id": "HGNC:3703", "url": "https://alliancegenome.org/gene/HGNC:3703#orthology", "database": "AGR" }, { "id": "MGI:1338762", "url": "https://alliancegenome.org/gene/MGI:1338762#orthology", "database": "AGR" }, { "id": "RGD:61963", "url": "https://alliancegenome.org/gene/RGD:61963#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-041010-121", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041010-121#orthology", "database": "AGR" }, { "id": "FB:FBgn0085354", "url": "https://alliancegenome.org/gene/FB:FBgn0085354#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9WTX7-1", "protein_name": "Four and a half LIM domains protein 5", "gene_name": "Fhl5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTSSQFDCQYCTSSLIGKKYVLKDDNLYCISCYDRIFSNYCEQCKEPIESDSKDLCYKNRHWHEGCFRCNKCHHSLVEKPFVAKDDRLLCTDCYSNECSSKCFHCKRTIMPGSRKMEFKGNYWHETCFVCEHCRQPIGTKPLISKESGNYCVPCFEKEFAHYCNFCKKVITSGGITFRDQIWHKECFLCSGCRKELYEEAFMSKDDFPFCLDCYNHLYAKKCAACTKPITGLRGAKFICFQDRQWHSECFNCGKCSVSLVGEGFLTHNMEILCRKCGSGADTDA", "length": 284 }, "evidence": [ { "id": "FB:FBgn0085354", "url": "https://alliancegenome.org/gene/FB:FBgn0085354#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "skeletal muscle tissue regeneration", "id": "GO:0043403", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043403", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "B0V234", "url": "https://www.uniprot.org/uniprotkb/B0V234" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B0V234", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V234" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 98, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 8 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B0V2R6-1", "uniprot_ac": "B0V2R6", "uniprot_id": "B0V2R6_DANRE", "mass": { "chemical_mass": 29425.0, "monoisotopic_mass": 29425.0 }, "refseq": { "ac": "NP_001116785", "name": "uncharacterized protein LOC796762", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116785" }, "gene_names": [ { "name": "fam78bb", "type": "recommended", "evidence": [ { "id": "B0V2R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V2R6" } ] }, { "name": "fam78bb", "type": "synonym", "evidence": [ { "id": "NP_001116785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116785" } ] }, { "name": "fj35d09", "type": "synonym", "evidence": [ { "id": "NP_001116785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116785" }, { "id": "B0V2R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V2R6" } ] }, { "name": "si:ch211-228b23.3", "type": "synonym", "evidence": [ { "id": "NP_001116785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116785" }, { "id": "B0V2R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V2R6" } ] }, { "name": "wu:fj35d09", "type": "synonym", "evidence": [ { "id": "NP_001116785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116785" }, { "id": "B0V2R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V2R6" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC796762", "type": "synonym", "evidence": [ { "id": "B0V2R6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V2R6/entry#names_and_taxonomy" } ] }, { "name": "family with sequence similarity 78, member B b", "type": "synonym", "evidence": [ { "id": "NP_001116785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116785" } ] }, { "name": "uncharacterized protein LOC796762", "type": "synonym", "evidence": [ { "id": "NP_001116785", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116785" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from CT025750.7. On Apr 11, 2008 this sequence version replaced XP_001337148.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001116785", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116785" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0V2R6", "url": "https://www.uniprot.org/uniprotkb/B0V2R6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam78bb", "url": "https://www.uniprot.org/uniprotkb/B0V2R6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-7811", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7811", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000113552", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000113552", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "796762", "url": "https://www.ncbi.nlm.nih.gov/gene/796762", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:796762", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796762", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "IDHCPTI", "url": "https://omabrowser.org/oma/group/IDHCPTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B0V2R6", "url": "https://www.orthodb.org/?gene=B0V2R6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31655", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31655", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31655:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31655:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001116785", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116785", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0V2R6", "url": "https://www.uniprot.org/uniprotkb/B0V2R6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0V2R6-1", "url": "https://www.uniprot.org/uniprotkb/B0V2R6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-7811", "url": "https://zfin.org/ZDB-GENE-030131-7811", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGCLQSVACKPRIKRENIVVYDVSATIDHCPTVIEENSPIVLRYKTPYFKASARIVMPPIPRNETWVVGWIQACTQMEFYNTYGDLGMSSWELPELREGLVKAISDSDGLSYPWYGNTTETVTLSGPTSKPSRFTVSMNDNFYPSVTWAVPVSESNVPLLTRIKRDQSFTTWLVALNVTTQEKILLQTVKWRMKVDIAVDPSKPLSSRARLIGRVHQDQPKVLTHMEQIPPNALGKPNANDAQVLMWRPKRGPPLVVIPSK", "length": 261, "header": "tr|B0V2R6-1|B0V2R6_DANRE Isoform 1 of Uncharacterized protein LOC796762 OS=Danio rerio OX=7955 GN=fam78bb PE=4 SV=1 CANONICAL=B0V2R6-1" }, "isoforms": [ { "isoform_ac": "B0V2R6-1", "url": "https://www.uniprot.org/uniprotkb/B0V2R6/entry#B0V2R6-1", "sequence": { "sequence": "MGCLQSVACKPRIKRENIVVYDVSATIDHCPTVIEENSPIVLRYKTPYFKASARIVMPPIPRNETWVVGWIQACTQMEFYNTYGDLGMSSWELPELREGLVKAISDSDGLSYPWYGNTTETVTLSGPTSKPSRFTVSMNDNFYPSVTWAVPVSESNVPLLTRIKRDQSFTTWLVALNVTTQEKILLQTVKWRMKVDIAVDPSKPLSSRARLIGRVHQDQPKVLTHMEQIPPNALGKPNANDAQVLMWRPKRGPPLVVIPSK", "length": 261, "header": "tr|B0V2R6-1|B0V2R6_DANRE Isoform 1 of Uncharacterized protein LOC796762 OS=Danio rerio OX=7955 GN=fam78bb PE=4 SV=1 CANONICAL=B0V2R6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:796762", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:796762", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AGD7-1", "protein_name": "Family with sequence similarity 78, member B", "gene_name": "Fam78b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCIQSITCKARIRRENIVVYDVCATIDQCPTRIEETSPIVLRYKTPYFKASARVVMPPIPRHETWVVGWIQACNQMEFFNTYSDLGMSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSDSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPLQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGPPLVVIPPK", "length": 261 }, "evidence": [ { "id": "RGD:1564387", "url": "https://alliancegenome.org/gene/RGD:1564387#orthology", "database": "AGR" }, { "id": "MGI:2443050", "url": "https://alliancegenome.org/gene/MGI:2443050#orthology", "database": "AGR" }, { "id": "HGNC:13495", "url": "https://alliancegenome.org/gene/HGNC:13495#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7811", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7811#orthology", "database": "AGR" }, { "id": "B0V2R6", "url": "https://omabrowser.org/oma/group/B0V2R6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { 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"MGCLQSVACKARVRREHIVVSDVSATIEPAATAIEESSPVVLRYRTPYFRASARVLMPPIARRHTWVVGWIQACNHMEFYNTYSDLGVSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSNSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPMQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGQPIVVIPPK", "length": 261 }, "evidence": [ { "id": "B0V2R6", "url": "https://omabrowser.org/oma/group/B0V2R6/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1S245-1", "protein_name": "Family with sequence similarity 78 member B", "gene_name": "FAM78B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MGCIQSITCKARIRRENIVVYDVCATIDQCPTRIEETSPIVLRYKTPYFKASARVVMPPIPRHETWVVGWIQACNQMEFFNTYSDLGMSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSDSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPLQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGPPLVVIPPK", "length": 261 }, "evidence": [ { "id": "B0V2R6", "url": "https://omabrowser.org/oma/group/B0V2R6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5VT40-1", "protein_name": "Protein FAM78B", "gene_name": "FAM78B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCIQSITCKARIRRENIVVYDVCATIDQCPTRIEETSPIVLRYKTPYFKASARVVMPPIPRHETWVVGWIQACNQMEFFNTYSDLGMSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSDSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPLQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGPPLVVIPPK", "length": 261 }, "evidence": [ { "id": "RGD:1564387", "url": "https://alliancegenome.org/gene/RGD:1564387#orthology", "database": "AGR" }, { "id": "MGI:2443050", "url": "https://alliancegenome.org/gene/MGI:2443050#orthology", "database": "AGR" }, { "id": "HGNC:13495", "url": "https://alliancegenome.org/gene/HGNC:13495#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7811", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7811#orthology", "database": "AGR" }, { "id": "B0V2R6", "url": "https://omabrowser.org/oma/group/B0V2R6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BQN5-1", "protein_name": "Protein FAM78B", "gene_name": "Fam78b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCIQSITCKARIRRENIVVYDVCATIDQCPTRIEETSPIVLRYKTPYFKASARVVMPPIPRHETWVVGWIQACNQMEFFNTYSDLGMSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSDSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPLQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGPPLVVIPPK", "length": 261 }, "evidence": [ { "id": "RGD:1564387", "url": "https://alliancegenome.org/gene/RGD:1564387#orthology", "database": "AGR" }, { "id": "MGI:2443050", "url": "https://alliancegenome.org/gene/MGI:2443050#orthology", "database": "AGR" }, { "id": "HGNC:13495", "url": "https://alliancegenome.org/gene/HGNC:13495#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7811", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7811#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 117, "end_pos": 119, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 63, "end_pos": 65, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 117, "end_pos": 119 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 63, "end_pos": 65 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B0V2R9-1", "uniprot_ac": "B0V2R9", "uniprot_id": "B0V2R9_DANRE", "mass": { "chemical_mass": 44089.0, "monoisotopic_mass": 44089.0 }, "refseq": { "ac": "NP_001116733", "name": "uncharacterized protein LOC561637", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116733" }, "gene_names": [ { "name": "si:dkeyp-110g5.4", "type": "recommended", "evidence": [ { "id": "B0V2R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V2R9" } ] }, { "name": "si:dkeyp-110g5.4", "type": "synonym", "evidence": [ { "id": "NP_001116733", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116733" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC561637", "type": "synonym", "evidence": [ { "id": "B0V2R9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B0V2R9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC561637", "type": "synonym", "evidence": [ { "id": "NP_001116733", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116733" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01037795.1, SRR32588734.1058372.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000008.1. On Apr 11, 2008 this sequence version replaced XP_705999.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001116733", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116733" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B0V2R9", "url": "https://www.uniprot.org/uniprotkb/B0V2R9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkeyp-110g5.4", "url": "https://www.uniprot.org/uniprotkb/B0V2R9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-452", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-452", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092482", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092482", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "561637", "url": "https://www.ncbi.nlm.nih.gov/gene/561637", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:561637", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561637", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "B0V2R9", "url": "https://www.orthodb.org/?gene=B0V2R9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001116733", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001116733", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B0V2R9", "url": "https://www.uniprot.org/uniprotkb/B0V2R9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B0V2R9-1", "url": "https://www.uniprot.org/uniprotkb/B0V2R9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-452", "url": "https://zfin.org/ZDB-GENE-081104-452", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MENTVVYIPKEACVKNIPLQSLSSSLSRKISVALFLRESQKQTVTWICPVELRQKQVSLGKESSRLRLTQITPGQFLLPVLSSSITAYKVLRTDLKTNKPEVQFSGQEETEVTSLASIRNSVHRNAIIVCNGQIFLSVRKTRCRRVRLQNCPAATEGVGSASPGQHQQINNTDSCQAQALRETSDTPQQNQVQDVQPPDQELNLNTENSALVQKIPEEMPEQCWTEKECQKVQDVQPPDQELNLNTENSPLVQKISEEMPEQSWTEKECQKNAELTSESRSQSSTPLETPLDLESSHEALSMEETDCQPKILQQILQTSSGISQQPEAAGGEGETDQDDSERLEALVLPRVESCLAFDFEQLAHEERINRLRAQLRQKEAALSIFNLKPTDQI", "length": 393, "header": "tr|B0V2R9-1|B0V2R9_DANRE Isoform 1 of Uncharacterized protein LOC561637 OS=Danio rerio OX=7955 GN=si:dkeyp-110g5.4 PE=4 SV=1 CANONICAL=B0V2R9-1" }, "isoforms": [ { "isoform_ac": "B0V2R9-1", "url": "https://www.uniprot.org/uniprotkb/B0V2R9/entry#B0V2R9-1", "sequence": { "sequence": "MENTVVYIPKEACVKNIPLQSLSSSLSRKISVALFLRESQKQTVTWICPVELRQKQVSLGKESSRLRLTQITPGQFLLPVLSSSITAYKVLRTDLKTNKPEVQFSGQEETEVTSLASIRNSVHRNAIIVCNGQIFLSVRKTRCRRVRLQNCPAATEGVGSASPGQHQQINNTDSCQAQALRETSDTPQQNQVQDVQPPDQELNLNTENSALVQKIPEEMPEQCWTEKECQKVQDVQPPDQELNLNTENSPLVQKISEEMPEQSWTEKECQKNAELTSESRSQSSTPLETPLDLESSHEALSMEETDCQPKILQQILQTSSGISQQPEAAGGEGETDQDDSERLEALVLPRVESCLAFDFEQLAHEERINRLRAQLRQKEAALSIFNLKPTDQI", "length": 393, "header": "tr|B0V2R9-1|B0V2R9_DANRE Isoform 1 of Uncharacterized protein LOC561637 OS=Danio rerio OX=7955 GN=si:dkeyp-110g5.4 PE=4 SV=1 CANONICAL=B0V2R9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B0V2R9", "url": "https://www.uniprot.org/uniprotkb/B0V2R9" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:561637", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561637", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" } ], 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"glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": 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The reference sequence was derived from JBMGRA010000020.1. 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"MIQRDRVCGVTNQQQQGEAVDEVMEPLEKHEEIPKPRQVKTEDEEVLSMFHKEEAERKSRRTPRGTKPYYCTQCGKSFSVAARFRRHQRIHSGHRPYQCPLCHTGFTSQENLSEHLAHAHTQASSKPHRCTHCGKGFVRPGKLCIHMRVHTGERPHRCADCGKSFKSAGELQRHTAIHTEIKTHQCSECESSFRRSTHLLRHMRTHSGERPHQCMSCGRRYSRSDHLRSHRCTHTHTDSKTRRVQC", "length": 246, "header": "tr|B0VJZ9-1|B0VJZ9_DANRE Isoform 1 of C2H2-type zinc finger protein OS=Danio rerio OX=7955 GN=ch1073-192f24.2 PE=3 SV=1 CANONICAL=B0VJZ9-1" }, "isoforms": [ { "isoform_ac": "A0AC58I525-1", "url": "https://www.uniprot.org/uniprotkb/B0VJZ9/entry#A0AC58I525-1", "sequence": { "sequence": "MEPLEKHEEIPKPRQVKTEDEEVLSMFHKEEAERKSRRTPRGTKPYYCTQCGKSFSVAARFRRHQRIHSGHRPYQCPLCHTGFTSQENLSEHLAHAHTQASSKPHRCTHCGKGFVRPGKLCIHMRVHTGERPHRCADCGKSFKSAGELQRHTAIHTEIKTHQCSECESSFRRSTHLLRHMRTHSGERPHQCMSCGRRYSRSDHLRSHRCTHTHTDSKTRRVQC", "length": 223, "header": "tr|A0AC58I525-1|A0AC58I525_DANRE Computationally mapped isoform of C2H2-type zinc finger protein isoform X1 OS=Danio rerio OX=7955 GN=zgc:101562 PE=3 SV=1 CANONICAL=B0VJZ9-1" }, "locus": {} }, { "isoform_ac": "B0VJZ9-1", "url": "https://www.uniprot.org/uniprotkb/B0VJZ9/entry#B0VJZ9-1", "sequence": { "sequence": "MIQRDRVCGVTNQQQQGEAVDEVMEPLEKHEEIPKPRQVKTEDEEVLSMFHKEEAERKSRRTPRGTKPYYCTQCGKSFSVAARFRRHQRIHSGHRPYQCPLCHTGFTSQENLSEHLAHAHTQASSKPHRCTHCGKGFVRPGKLCIHMRVHTGERPHRCADCGKSFKSAGELQRHTAIHTEIKTHQCSECESSFRRSTHLLRHMRTHSGERPHQCMSCGRRYSRSDHLRSHRCTHTHTDSKTRRVQC", "length": 246, "header": "tr|B0VJZ9-1|B0VJZ9_DANRE Isoform 1 of C2H2-type zinc finger protein OS=Danio rerio OX=7955 GN=ch1073-192f24.2 PE=3 SV=1 CANONICAL=B0VJZ9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A versatile gene trap to visualize and interrogate the function of the vertebrate proteome.", "journal": "Genes Dev.", "date": "2011", "authors": "Trinh Le A, Hochgreb Tatiana, Graham Matthew, Wu David, Ruf-Zamojski Frederique, Jayasena Chathurani S, Saxena Ankur, Hawk Rasheeda, Gonzalez-Serricchio Aidyl, Dixson Alana, Chow Elly, 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"database": "UniProtKB", "id": "B0VJZ9", "url": "https://www.uniprot.org/uniprotkb/B0VJZ9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "B0VJZ9", "url": "https://www.uniprot.org/uniprotkb/B0VJZ9" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "B0VJZ9", "url": "https://www.uniprot.org/uniprotkb/B0VJZ9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { 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"monoisotopic_mass": 9278.0 }, "refseq": { "ac": "NP_001153455", "name": "LYR motif-containing protein 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153455" }, "gene_names": [ { "name": "lyrm9", "type": "recommended", "evidence": [ { "id": "B3DFV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B3DFV0" } ] }, { "name": "lyrm9", "type": "synonym", "evidence": [ { "id": "NP_001153455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153455" } ] }, { "name": "zgc:193694", "type": "synonym", "evidence": [ { "id": "NP_001153455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153455" }, { "id": "B3DFV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B3DFV0" } ] }, { "name": "zgc:193700", "type": "synonym", "evidence": [ { "id": "NP_001153455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153455" } ] } ], "protein_names": [ { "name": "LYR motif-containing protein 9", "type": "recommended", "evidence": [ { "id": "B3DFV0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B3DFV0/entry#names_and_taxonomy" } ] }, { "name": "LYR motif-containing protein 9", "type": "synonym", "evidence": [ { "id": "NP_001153455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153455" } ] }, { "name": "UPF0631 protein C17orf108 homolog", "type": "synonym", "evidence": [ { "id": "NP_001153455", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001153455" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01025695.1, EH574050.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1, EH552928.1 and EH574050.1. 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"https://bgee.org/?page=gene&gene_id=ENSDARG00000075528", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd20269", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd20269", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "563525", "url": "https://www.ncbi.nlm.nih.gov/gene/563525", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR008011", "url": "https://www.ebi.ac.uk/interpro/entry/IPR008011", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:563525", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563525", "database": "KEGG Pathway", "categories": [ "Enzyme and 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"database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B3DFV0", "url": "https://www.uniprot.org/uniprotkb/B3DFV0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B3DFV0-1", "url": "https://www.uniprot.org/uniprotkb/B3DFV0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081022-28", "url": "https://zfin.org/ZDB-GENE-081022-28", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSPVAGAKFVRTPLQLYRYLLRCCRLLPSEAMQKHYQHAIRQSYNSHVDEDDPQRIQMIIQRAISDADWILNKYTKKK", "length": 78, "header": "sp|B3DFV0-1|LYRM9_DANRE Isoform 1 of LYR motif-containing protein 9 OS=Danio rerio OX=7955 GN=lyrm9 PE=3 SV=1 CANONICAL=B3DFV0-1" }, "isoforms": [ { "isoform_ac": "B3DFV0-1", "url": "https://www.uniprot.org/uniprotkb/B3DFV0/entry#B3DFV0-1", "sequence": { "sequence": "MSPVAGAKFVRTPLQLYRYLLRCCRLLPSEAMQKHYQHAIRQSYNSHVDEDDPQRIQMIIQRAISDADWILNKYTKKK", "length": 78, "header": "sp|B3DFV0-1|LYRM9_DANRE Isoform 1 of LYR motif-containing protein 9 OS=Danio rerio OX=7955 GN=lyrm9 PE=3 SV=1 CANONICAL=B3DFV0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:563525", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563525", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8W4FJA3-1", "protein_name": "LYR motif-containing protein 9", "gene_name": "LYRM9", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MAPLPGAELVQRPLQLYRYLLRCCRQLPTKGIQEHYKHAVRQSFRVHSDEDNPERIQQIIKRAIEDADWILNKYKKQN", "length": 78 }, "evidence": [ { "id": "B3DFV0", "url": "https://omabrowser.org/oma/group/B3DFV0/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A9J7JYM4-1", "protein_name": "LYR motif-containing protein 9", "gene_name": "Lyrm9", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSHKLGCLPGRQGWGSQMAPLPGAELVQTPLQLYRYLLRCCRQLPTKGIQEHYKHAVRQSFRVHSDEDNPERILQIIKRAIEDADWIMNKYKKQN", "length": 96 }, "evidence": [ { "id": "B3DFV0", "url": "https://omabrowser.org/oma/group/B3DFV0/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A8MSI8-1", "protein_name": "LYR motif-containing protein 9", "gene_name": "LYRM9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAPLPGAELVRRPLQLYRYLLRCCQQLPTKGIQQHYKHAVRQSFRVHSDEDNPERIQQIIKRAIEDADWIMNKYKKQN", "length": 78 }, "evidence": [ { "id": "RGD:1562012", "url": "https://alliancegenome.org/gene/RGD:1562012#orthology", "database": "AGR" }, { "id": "MGI:1913524", "url": "https://alliancegenome.org/gene/MGI:1913524#orthology", "database": "AGR" }, { "id": "HGNC:27314", "url": "https://alliancegenome.org/gene/HGNC:27314#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081022-28", "url": 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"B3DFV0", "url": "https://omabrowser.org/oma/group/B3DFV0/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UN90-1", "protein_name": "LYR motif-containing protein 9", "gene_name": "Lyrm9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAPLPGAELVQTPLQLYRYLLRCCRQLPTKGIQEHYKHAVRQSFQVHSDEDNSERIQQIIKRAIEDADWIMNKYRKQN", "length": 78 }, "evidence": [ { "id": "RGD:1562012", "url": "https://alliancegenome.org/gene/RGD:1562012#orthology", "database": "AGR" }, { "id": "MGI:1913524", "url": "https://alliancegenome.org/gene/MGI:1913524#orthology", "database": "AGR" }, { "id": "HGNC:27314", "url": "https://alliancegenome.org/gene/HGNC:27314#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081022-28", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081022-28#orthology", "database": "AGR" }, { "id": "B3DFV0", "url": "https://omabrowser.org/oma/group/B3DFV0/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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"https://www.ncbi.nlm.nih.gov/protein/NP_001154965" }, "gene_names": [ { "name": "si:dkey-261e22.4", "type": "recommended", "evidence": [ { "id": "B3DGJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B3DGJ2" } ] }, { "name": "OCC-1", "type": "synonym", "evidence": [ { "id": "NP_001154965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001154965" } ] }, { "name": "si:dkey-261e22.4", "type": "synonym", "evidence": [ { "id": "NP_001154965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001154965" } ] } ], "protein_names": [ { "name": "Overexpressed in colon carcinoma 1 protein homolog", "type": "recommended", "evidence": [ { "id": "B3DGJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B3DGJ2/entry#names_and_taxonomy" } ] }, { "name": "OCC-1", "type": "synonym", "evidence": [ { "id": "B3DGJ2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B3DGJ2/entry#names_and_taxonomy" } ] }, { "name": "overexpressed in colon carcinoma 1 protein homolog", "type": "synonym", "evidence": [ { "id": "NP_001154965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001154965" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC162416.1, EB764388.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476743 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC162416.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001154965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001154965" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B3DGJ2", "url": "https://www.uniprot.org/uniprotkb/B3DGJ2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-261e22.4", "url": "https://www.uniprot.org/uniprotkb/B3DGJ2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041210-161", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-161", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "B3DGJ2", "url": "https://alphafold.ebi.ac.uk/entry/B3DGJ2", "database": "AlphaFoldDB", "categories": [] }, { "id": "100170803", "url": 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"categories": [ "Protein Classification", "Other" ] }, { "id": "PR:B3DGJ2", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:B3DGJ2", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001154965", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001154965", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B3DGJ2", "url": "https://www.uniprot.org/uniprotkb/B3DGJ2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B3DGJ2-1", "url": "https://www.uniprot.org/uniprotkb/B3DGJ2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-041210-161", "url": "https://zfin.org/ZDB-GENE-041210-161", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGCGNSTAASTTPGPAESAKDVQDDSSMDEEKRRNYGGVYVGIPADLTNETAGQTASTHKE", "length": 61, "header": "sp|B3DGJ2-1|OCC1_DANRE Isoform 1 of Overexpressed in colon carcinoma 1 protein homolog OS=Danio rerio OX=7955 GN=si:dkey-261e22.4 PE=3 SV=1 CANONICAL=B3DGJ2-1" }, "isoforms": [ { "isoform_ac": "B3DGJ2-1", "url": "https://www.uniprot.org/uniprotkb/B3DGJ2/entry#B3DGJ2-1", "sequence": { "sequence": "MGCGNSTAASTTPGPAESAKDVQDDSSMDEEKRRNYGGVYVGIPADLTNETAGQTASTHKE", "length": 61, "header": "sp|B3DGJ2-1|OCC1_DANRE Isoform 1 of Overexpressed in colon carcinoma 1 protein homolog OS=Danio rerio OX=7955 GN=si:dkey-261e22.4 PE=3 SV=1 CANONICAL=B3DGJ2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100170803", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100170803", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P0C913-1", "protein_name": "Overexpressed in colon carcinoma 1 protein homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCGNSTATSAAAGRGPTGAVKDTTEDSITEDDKRRNYGGVYVGLPSEAVNMASSQTKTVQKN", "length": 63 }, "evidence": [ { "id": "RGD:6495714", 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"https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041210-161#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 5, "end_pos": 7, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 49, "end_pos": 51 }, { "start_pos": 5, "end_pos": 7 } ] }, "class_list": [], "section_stats": [ { "table_id": 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"sort_fields": [] } ] }, { "uniprot_canonical_ac": "B7ZCZ6-1", "uniprot_ac": "B7ZCZ6", "uniprot_id": "B7ZCZ6_DANRE", "mass": { "chemical_mass": 79301.0, "monoisotopic_mass": 79301.0 }, "refseq": { "ac": "XP_009296326", "name": "uncharacterized protein si:ch211-236l14.1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296326" }, "gene_names": [ { "name": "si:ch211-236l14.1", "type": "recommended", "evidence": [ { "id": "B7ZCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZCZ6" } ] }, { "name": "si:ch211-211k8.4", "type": "synonym", "evidence": [ { "id": "B7ZCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZCZ6" } ] }, { "name": "si:ch211-236l14.1", "type": "synonym", "evidence": [ { "id": "XP_009296326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296326" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:ch211-211k8.4", "type": "synonym", "evidence": [ { "id": "B7ZCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZCZ6/entry#names_and_taxonomy" } ] }, { "name": "Uncharacterized protein si:ch211-236l14.1", "type": "synonym", "evidence": [ { "id": "B7ZCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZCZ6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:ch211-236l14.1", "type": "synonym", "evidence": [ { "id": "XP_009296326", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296326" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009296326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296326" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B7ZCZ6", "url": "https://www.uniprot.org/uniprotkb/B7ZCZ6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-236l14.1", "url": "https://www.uniprot.org/uniprotkb/B7ZCZ6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-492", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-492", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000095051", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000095051", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100003901", "url": "https://www.ncbi.nlm.nih.gov/gene/100003901", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "100329582", "url": "https://www.ncbi.nlm.nih.gov/gene/100329582", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006612", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006612", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100003901", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003901", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETRHQNC", "url": "https://omabrowser.org/oma/group/ETRHQNC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "FNCARIP", "url": "https://omabrowser.org/oma/group/FNCARIP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B7ZCZ6", "url": "https://www.orthodb.org/?gene=B7ZCZ6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31751", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31751", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31751:SF44", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31751:SF44", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009296326", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009296326", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B7ZCZ6", "url": "https://www.uniprot.org/uniprotkb/B7ZCZ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B7ZCZ6-1", "url": "https://www.uniprot.org/uniprotkb/B7ZCZ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050208-594", "url": "https://zfin.org/ZDB-GENE-050208-594", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] }, { "id": "ZDB-GENE-081104-492", "url": "https://zfin.org/ZDB-GENE-081104-492", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPPREHPCAILGCKAQHKSLHRLPANEQQRLKWLSFIFEDKVPENVPKLLYVCANHFSVDCLENAGQYNSGFASKLFLKTGSVPTIRDPVSLQATTSTKSNKVDVACQTEPFHTSLHSVGTQLSFRTLQAKRRSTSVQTTISSFELTVPSASSTAFMTSTPLKPSLKRPRLELEEEEEEEEAEETLTESKIIAQDSDVTFDPAEECTSATEPTDLSIQECPVHNIAKFIVYETCLMELFSDCPVCQRRCDVKSQRLGTFLSVQQVCPHCEFVRKWNSQPIIGSTPAGNLHLSAAVYLSGASFFVVEKVFAAMKLHIFKYNSFRRHARLCIEPAIVHKWRNWQSEMLEQLSRRENVIVGGDMRADSPGHSAKYGSYTMMDLATNTVVDLQLVQSNEVGGSYHMEKEGLKRSLDLLDARGVRLECIITDRHPQIQKYLRDRNVTQFYDVWHIEKGISKKLDKICQIKGCEKLRKWLRSIKNHIYWTAASSTTGPERVAKWTSILNHVQDKHVHEDPNFPACLHPQRISRDKNKWLSAATMPFYKLEKVLANKRILKDVAKLSPHHQTSTIEAFHSVILRFAPKNVVFPFLGMLCRLYLAALHYNENAGRPQATSATGKPIYKLAFPKAKKGEYRVREVKTQQTFGYVEELLDLIFNQVFVDPSPYVDEVLGIHIPPALSSAYDRPEMEEAISSRVTRFNQ", "length": 698, "header": "tr|B7ZCZ6-1|B7ZCZ6_DANRE Isoform 1 of Uncharacterized protein si:ch211-236l14.1 OS=Danio rerio OX=7955 GN=si:ch211-236l14.1 PE=4 SV=1 CANONICAL=B7ZCZ6-1" }, "isoforms": [ { "isoform_ac": "B7ZCZ6-1", "url": "https://www.uniprot.org/uniprotkb/B7ZCZ6/entry#B7ZCZ6-1", "sequence": { "sequence": "MPPREHPCAILGCKAQHKSLHRLPANEQQRLKWLSFIFEDKVPENVPKLLYVCANHFSVDCLENAGQYNSGFASKLFLKTGSVPTIRDPVSLQATTSTKSNKVDVACQTEPFHTSLHSVGTQLSFRTLQAKRRSTSVQTTISSFELTVPSASSTAFMTSTPLKPSLKRPRLELEEEEEEEEAEETLTESKIIAQDSDVTFDPAEECTSATEPTDLSIQECPVHNIAKFIVYETCLMELFSDCPVCQRRCDVKSQRLGTFLSVQQVCPHCEFVRKWNSQPIIGSTPAGNLHLSAAVYLSGASFFVVEKVFAAMKLHIFKYNSFRRHARLCIEPAIVHKWRNWQSEMLEQLSRRENVIVGGDMRADSPGHSAKYGSYTMMDLATNTVVDLQLVQSNEVGGSYHMEKEGLKRSLDLLDARGVRLECIITDRHPQIQKYLRDRNVTQFYDVWHIEKGISKKLDKICQIKGCEKLRKWLRSIKNHIYWTAASSTTGPERVAKWTSILNHVQDKHVHEDPNFPACLHPQRISRDKNKWLSAATMPFYKLEKVLANKRILKDVAKLSPHHQTSTIEAFHSVILRFAPKNVVFPFLGMLCRLYLAALHYNENAGRPQATSATGKPIYKLAFPKAKKGEYRVREVKTQQTFGYVEELLDLIFNQVFVDPSPYVDEVLGIHIPPALSSAYDRPEMEEAISSRVTRFNQ", "length": 698, "header": "tr|B7ZCZ6-1|B7ZCZ6_DANRE Isoform 1 of Uncharacterized protein si:ch211-236l14.1 OS=Danio rerio OX=7955 GN=si:ch211-236l14.1 PE=4 SV=1 CANONICAL=B7ZCZ6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100003901", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100003901", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "B7ZCZ6", "url": "https://www.uniprot.org/uniprotkb/B7ZCZ6" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B7ZCZ6", "url": "https://www.uniprot.org/uniprotkb/B7ZCZ6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 440, "end_pos": 442, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B7ZCZ6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZCZ6" }, { "id": "PS50950", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50950" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "THAP-type", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 87, "start_aa": "Met", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 440, "end_pos": 442 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B7ZD59-1", "uniprot_ac": "B7ZD59", "uniprot_id": "B7ZD59_DANRE", "mass": { "chemical_mass": 31051.0, "monoisotopic_mass": 31051.0 }, "refseq": { "ac": "NP_001139099", "name": "uncharacterized protein LOC100005086", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139099" }, "gene_names": [ { "name": "si:ch211-93g23.2", "type": "recommended", "evidence": [ { "id": "B7ZD59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZD59" } ] }, { "name": "si:ch211-93g23.2", "type": "synonym", "evidence": [ { "id": "NP_001139099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139099" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC100005086", "type": "synonym", "evidence": [ { "id": "B7ZD59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZD59/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC100005086", "type": "synonym", "evidence": [ { "id": "NP_001139099", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139099" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH502191.1, EH518739.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000001.1. On Jun 5, 2025 this sequence version replaced NP_001139099.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001139099", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139099" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B7ZD59", "url": "https://www.uniprot.org/uniprotkb/B7ZD59" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-93g23.2", "url": "https://www.uniprot.org/uniprotkb/B7ZD59", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090312-164", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-164", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000070558", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000070558", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd02440", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd02440", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100005086", "url": "https://www.ncbi.nlm.nih.gov/gene/100005086", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029063", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029063", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051052", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051052", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100005086", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005086", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EWNECLQ", "url": "https://omabrowser.org/oma/group/EWNECLQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B7ZD59", "url": "https://www.orthodb.org/?gene=B7ZD59", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44942", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44942", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44942:SF9", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44942:SF9", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF08241", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08241", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001139099", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139099", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58HIS6", "url": "https://www.uniprot.org/uniprotkb/A0AC58HIS6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HIS6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HIS6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLK0", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLK0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HLK0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HLK0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B7ZD59", "url": "https://www.uniprot.org/uniprotkb/B7ZD59", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B7ZD59-1", "url": "https://www.uniprot.org/uniprotkb/B7ZD59-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090312-164", "url": "https://zfin.org/ZDB-GENE-090312-164", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAQRHFEGKDHVESYQRHRVSPPQELIDEVLNFLRKRINTDLDLAVDVGCGSGQGTELLAPYFLTVVGTDISPAQLKIASDKDHPANICYRESPAEDLPFEDSIADLVSSMSAAHWFDHPRFLQEVDRILKPGGCLALLSYTMDFELEYGESTSKLNNICEEFYAALHPFRKAYIGSSSLQVYKNIYDSISYADKEWHECLKSRRIMPLSKFIGLVETFSTYQGFLEKDPVKAKKLSKTITDRLLEAMGASSTDTELTVIVKYFYILASKPRKS", "length": 274, "header": "tr|B7ZD59-1|B7ZD59_DANRE Isoform 1 of Uncharacterized protein LOC100005086 OS=Danio rerio OX=7955 GN=si:ch211-93g23.2 PE=4 SV=1 CANONICAL=B7ZD59-1" }, "isoforms": [ { "isoform_ac": "A0AC58HIS6-1", "url": "https://www.uniprot.org/uniprotkb/B7ZD59/entry#A0AC58HIS6-1", "sequence": { "sequence": "MSAAHWFDHPRFLQEVDRILKPGGCLALLSYTMDFELEYGESTSKLNKICEEFYAALHPFRKAYIGSSSLQVYKNIYDSISYADKEWHECLKSRRIMPLSKFIGLVETFSTYQGFLEKDPVKAKKLSKTITDRLLEAMGASSTDTELTVIVKYFYILASKPRKS", "length": 164, "header": "tr|A0AC58HIS6-1|A0AC58HIS6_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=si:ch211-93g23.2 PE=4 SV=1 CANONICAL=B7ZD59-1" }, "locus": {} }, { "isoform_ac": "A0AC58HLK0-1", "url": "https://www.uniprot.org/uniprotkb/B7ZD59/entry#A0AC58HLK0-1", "sequence": { "sequence": "MLQEVDRILKPGGCLALLSYTMDFELEYGESTSKLNKICEEFYAALHPFRKAYIGSSSLQVYKNIYDSISYADKEWHECLKSRRIMPLSKFIGLVETFSTYQGFLEKDPVKAKKLSKTITDRLLEAMGASSTDTELTVIVKYFYILASKPRKS", "length": 153, "header": "tr|A0AC58HLK0-1|A0AC58HLK0_DANRE Computationally mapped isoform of Uncharacterized protein isoform X2 OS=Danio rerio OX=7955 GN=si:ch211-93g23.2 PE=4 SV=1 CANONICAL=B7ZD59-1" }, "locus": {} }, { "isoform_ac": "B7ZD59-1", "url": "https://www.uniprot.org/uniprotkb/B7ZD59/entry#B7ZD59-1", "sequence": { "sequence": "MAQRHFEGKDHVESYQRHRVSPPQELIDEVLNFLRKRINTDLDLAVDVGCGSGQGTELLAPYFLTVVGTDISPAQLKIASDKDHPANICYRESPAEDLPFEDSIADLVSSMSAAHWFDHPRFLQEVDRILKPGGCLALLSYTMDFELEYGESTSKLNNICEEFYAALHPFRKAYIGSSSLQVYKNIYDSISYADKEWHECLKSRRIMPLSKFIGLVETFSTYQGFLEKDPVKAKKLSKTITDRLLEAMGASSTDTELTVIVKYFYILASKPRKS", "length": 274, "header": "tr|B7ZD59-1|B7ZD59_DANRE Isoform 1 of Uncharacterized protein LOC100005086 OS=Danio rerio OX=7955 GN=si:ch211-93g23.2 PE=4 SV=1 CANONICAL=B7ZD59-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B7ZD59", "url": "https://www.uniprot.org/uniprotkb/B7ZD59" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B7ZD59", "url": "https://www.uniprot.org/uniprotkb/B7ZD59" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100005086", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005086", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "S-adenosylmethionine-dependent methyltransferase activity", "id": "GO:0008757", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008757", "evidence": [ { "database": "UniProtKB", "id": "B7ZD59", "url": "https://www.uniprot.org/uniprotkb/B7ZD59" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B7ZD59", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZD59" }, { "id": "PF08241", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF08241" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Methyltransferase type 11", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 137, "start_aa": "Val", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B7ZD93-1", "uniprot_ac": "B7ZD93", "uniprot_id": "B7ZD93_DANRE", "mass": { "chemical_mass": 25477.0, "monoisotopic_mass": 25477.0 }, "refseq": { "ac": "NP_001139062", "name": "mitochondrial transcription rescue factor 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139062" }, "gene_names": [ { "name": "mtres1", "type": "recommended", "evidence": [ { "id": "B7ZD93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZD93" } ] }, { "name": "fc21d12", "type": "synonym", "evidence": [ { "id": "NP_001139062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139062" }, { "id": "B7ZD93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZD93" } ] }, { "name": "mtres1", "type": "synonym", "evidence": [ { "id": "NP_001139062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139062" } ] }, { "name": "si:ch211-206k20.5", "type": "synonym", "evidence": [ { "id": "NP_001139062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139062" }, { "id": "B7ZD93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZD93" } ] }, { "name": "wu:fc21d12", "type": "synonym", "evidence": [ { "id": "NP_001139062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139062" }, { "id": "B7ZD93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZD93" } ] } ], "protein_names": [ { "name": "Mitochondrial transcription rescue factor 1", "type": "synonym", "evidence": [ { "id": "B7ZD93", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B7ZD93/entry#names_and_taxonomy" } ] }, { "name": "mitochondrial transcription rescue factor 1", "type": "synonym", "evidence": [ { "id": "NP_001139062", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139062" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01026813.1, EL650900.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000013.1. On Mar 5, 2009 this sequence version replaced XP_694006.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001139062", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139062" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B7ZD93", "url": "https://www.uniprot.org/uniprotkb/B7ZD93" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mtres1", "url": "https://www.uniprot.org/uniprotkb/B7ZD93", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-2912", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2912", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077614", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077614", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "565648", "url": "https://www.ncbi.nlm.nih.gov/gene/565648", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR057896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565648", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565648", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SLFCSCQ", "url": "https://omabrowser.org/oma/group/SLFCSCQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B7ZD93", "url": "https://www.orthodb.org/?gene=B7ZD93", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13633:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13633:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001139062", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139062", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B7ZD93", "url": "https://www.uniprot.org/uniprotkb/B7ZD93", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B7ZD93-1", "url": "https://www.uniprot.org/uniprotkb/B7ZD93-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-2912", "url": "https://zfin.org/ZDB-GENE-030131-2912", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MQSLSVQALALRQLGRLNSLQLLTPCHGSGLSMWCPRMLHARQLWGSATSQTHRTAMGPKSWDARQSWTLHQIRLKSTRKKGKQKAVHQEETEEETSDYEDEFPDDPGLPNNYKDNEKVVQSLRFDLVLKSGLDIARHSVEDSFYSLKLRLNGQKLSKKGKLVKVGDTLDQILSDDKERDTILLKRVILKKVVSETKDGEKLKVILRSWKSLQLPRKDVYKD", "length": 222, "header": "tr|B7ZD93-1|B7ZD93_DANRE Isoform 1 of Mitochondrial transcription rescue factor 1 OS=Danio rerio OX=7955 GN=mtres1 PE=1 SV=1 CANONICAL=B7ZD93-1" }, "isoforms": [ { "isoform_ac": "B7ZD93-1", "url": "https://www.uniprot.org/uniprotkb/B7ZD93/entry#B7ZD93-1", "sequence": { "sequence": "MQSLSVQALALRQLGRLNSLQLLTPCHGSGLSMWCPRMLHARQLWGSATSQTHRTAMGPKSWDARQSWTLHQIRLKSTRKKGKQKAVHQEETEEETSDYEDEFPDDPGLPNNYKDNEKVVQSLRFDLVLKSGLDIARHSVEDSFYSLKLRLNGQKLSKKGKLVKVGDTLDQILSDDKERDTILLKRVILKKVVSETKDGEKLKVILRSWKSLQLPRKDVYKD", "length": 222, "header": "tr|B7ZD93-1|B7ZD93_DANRE Isoform 1 of Mitochondrial transcription rescue factor 1 OS=Danio rerio OX=7955 GN=mtres1 PE=1 SV=1 CANONICAL=B7ZD93-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. 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Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B7ZD93", "url": "https://www.uniprot.org/uniprotkb/B7ZD93" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:565648", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565648", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3GXJ2-1", "protein_name": "Mitochondrial transcription rescue factor 1", "gene_name": "Mtres1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAVTGGRLLAGALRKPDSWIRLWGVLQGTSSHKLCASWNRYLYFSSTKLNASNYKTLFRNIFPLQLPGLLVSPKCIFPFSMRLKSNINSRKSTKKTLQKDADEEDSDEETHLPERSEPEEELEDDPGVVKDYKDLEKVVQSFRYDVILKTGLDIGRNKVEDAFYKGELRLNGEKLWKKSRTVKVGDTLDLLVGENKETGTEVVMRILLKTIYDEKTESDKHRVVLRRWKSLKLPKKSK", "length": 238 }, "evidence": [ { "id": "B7ZD93", "url": "https://omabrowser.org/oma/group/B7ZD93/", "database": "OMA" } ], 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validation or preliminary review. The reference sequence was derived from EH448898.1 and EH491902.1. On Feb 17, 2012 this sequence version replaced XP_001340314.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001243642", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243642" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A486", "url": "https://www.uniprot.org/uniprotkb/B8A486" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ifi27.8", "url": "https://www.uniprot.org/uniprotkb/B8A486", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-209", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-209", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092895", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092895", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100004663", "url": "https://www.ncbi.nlm.nih.gov/gene/100004663", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100004663", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004663", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YSASETC", "url": "https://omabrowser.org/oma/group/YSASETC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "PTHR16932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16932:SF37", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16932:SF37", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-9909505", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9909505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001243642", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243642", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8A486", "url": "https://www.uniprot.org/uniprotkb/B8A486", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A486-1", "url": "https://www.uniprot.org/uniprotkb/B8A486-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-209", "url": "https://zfin.org/ZDB-GENE-090313-209", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPTLPTLSTKTIIGATAGAVGAVALTPLALSMAGFTAAGITAGSTAAGMMSTAAVANGGGVAAGSVVALLQSAGAAGLSSAATAGVASVGGAAGGLLGGAVNWWRGK", "length": 107, "header": "tr|B8A486-1|B8A486_DANRE Isoform 1 of Interferon alpha inducible protein 27.8 OS=Danio rerio OX=7955 GN=ifi27.8 PE=3 SV=1 CANONICAL=B8A486-1" }, "isoforms": [ { "isoform_ac": "B8A486-1", "url": "https://www.uniprot.org/uniprotkb/B8A486/entry#B8A486-1", "sequence": { "sequence": "MPTLPTLSTKTIIGATAGAVGAVALTPLALSMAGFTAAGITAGSTAAGMMSTAAVANGGGVAAGSVVALLQSAGAAGLSSAATAGVASVGGAAGGLLGGAVNWWRGK", "length": 107, "header": "tr|B8A486-1|B8A486_DANRE Isoform 1 of Interferon alpha inducible protein 27.8 OS=Danio rerio OX=7955 GN=ifi27.8 PE=3 SV=1 CANONICAL=B8A486-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.", "journal": "J. 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Immunol.", "date": "2019", "authors": "Levraud Jean-Pierre, Jouneau Luc, Briolat Val\u00e9rie, Laghi Valerio, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "B8A486", "url": "https://www.uniprot.org/uniprotkb/B8A486" } ], "reference": [ { "type": "PubMed", "id": "31732531", "url": "https://glygen.org/publication/PubMed/31732531" } ] } ], "pathway": [ { "id": "dre:100004663", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004663", "resource": "KEGG Pathway" }, { "id": "R-DRE-9909505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9909505", "resource": "Reactome", "description": "Modulation of host responses by IFN-stimulated genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZTN9-1", "protein_name": "Interferon, alpha-inducible protein 27", "gene_name": "Ifi27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"name": "intrinsic apoptotic signaling pathway", "id": "GO:0097193", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097193", "evidence": [ { "database": "UniProtKB", "id": "B8A486", "url": "https://www.uniprot.org/uniprotkb/B8A486" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": 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"B8A489-1", "uniprot_ac": "B8A489", "uniprot_id": "B8A489_DANRE", "mass": { "chemical_mass": 13238.0, "monoisotopic_mass": 13238.0 }, "refseq": { "ac": "NP_001243574", "name": "interferon alpha inducible protein 27.6 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243574" }, "gene_names": [ { "name": "ifi27.6", "type": "recommended", "evidence": [ { "id": "B8A489", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A489" } ] }, { "name": "ifi27.6", "type": "synonym", "evidence": [ { "id": "NP_001243574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243574" } ] }, { "name": "isg12.6", "type": "synonym", "evidence": [ { "id": "NP_001243574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243574" }, { "id": "B8A489", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A489" } ] }, { "name": "si:dkey-188i13.9", "type": "synonym", "evidence": [ { "id": "NP_001243574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243574" }, { "id": "B8A489", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A489" } ] } ], "protein_names": [ { "name": "Interferon alpha inducible protein 27.6", "type": "synonym", "evidence": [ { "id": "B8A489", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A489/entry#names_and_taxonomy" } ] }, { "name": "interferon alpha inducible protein 27.6 precursor", "type": "synonym", "evidence": [ { "id": "NP_001243574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243574" } ] }, { "name": "interferon alpha-inducible protein 27-like", "type": "synonym", "evidence": [ { "id": "NP_001243574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243574" } ] }, { "name": "nterferon alpha inducible protein 27.6", "type": "synonym", "evidence": [ { "id": "NP_001243574", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243574" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH504730.1, EH506630.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505374, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EH504730.1. On Feb 16, 2012 this sequence version replaced XP_704861.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001243574", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243574" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A489", "url": "https://www.uniprot.org/uniprotkb/B8A489" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ifi27.6", "url": "https://www.uniprot.org/uniprotkb/B8A489", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-211", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-211", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000074754", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000074754", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "558363", "url": "https://www.ncbi.nlm.nih.gov/gene/558363", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009311", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009311", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038213", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038213", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558363", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558363", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PTHR16932", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16932", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16932:SF38", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16932:SF38", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06140", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06140", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-9909505", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9909505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001243574", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243574", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58H138", "url": "https://www.uniprot.org/uniprotkb/A0AC58H138", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H138-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H138-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A489", "url": "https://www.uniprot.org/uniprotkb/B8A489", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A489-1", "url": "https://www.uniprot.org/uniprotkb/B8A489-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-211", "url": "https://zfin.org/ZDB-GENE-090313-211", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKPGLFTVLGVAAGAVGTAVLAPVALTMAGFTSAGIAAGSLGASMMSSAAIANGGGVAAGSLVALLQSAGAAGLSAGATAAVASVGGAVGAAFGGAADFFSRPPPNNDDTTERLISKYMAIMLTLIIGLLMVAIIIVKEN", "length": 140, "header": "tr|B8A489-1|B8A489_DANRE Isoform 1 of Interferon alpha inducible protein 27.6 OS=Danio rerio OX=7955 GN=ifi27.6 PE=3 SV=1 CANONICAL=B8A489-1" }, "isoforms": [ { "isoform_ac": "A0AC58H138-1", "url": "https://www.uniprot.org/uniprotkb/B8A489/entry#A0AC58H138-1", "sequence": { "sequence": "MKPGLFTVLGVAAGAVGTAVLAPVALTMAGFTSAGIAAGSLGASMMSSAAIANGGGVAAGSLVALLQSAGKYRCCWTVCRSDRCSGISGWCSGCCVWRSSRFFLSSTSK", "length": 109, "header": "tr|A0AC58H138-1|A0AC58H138_DANRE Computationally mapped isoform of Interferon alpha inducible protein 27.6 isoform X1 OS=Danio rerio OX=7955 GN=ifi27.6 PE=3 SV=1 CANONICAL=B8A489-1" }, "locus": {} }, { "isoform_ac": "B8A489-1", "url": "https://www.uniprot.org/uniprotkb/B8A489/entry#B8A489-1", "sequence": { "sequence": "MKPGLFTVLGVAAGAVGTAVLAPVALTMAGFTSAGIAAGSLGASMMSSAAIANGGGVAAGSLVALLQSAGAAGLSAGATAAVASVGGAVGAAFGGAADFFSRPPPNNDDTTERLISKYMAIMLTLIIGLLMVAIIIVKEN", "length": 140, "header": "tr|B8A489-1|B8A489_DANRE Isoform 1 of Interferon alpha inducible protein 27.6 OS=Danio rerio OX=7955 GN=ifi27.6 PE=3 SV=1 CANONICAL=B8A489-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.", "journal": "J. Immunol.", "date": "2014", "authors": "Briolat Val\u00e9rie, Jouneau Luc, Carvalho Ralph, Palha Nuno, Langevin Christelle, Herbomel Philippe, Schwartz Olivier, Spaink Herman P, Levraud Jean-Pierre, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "B8A489", "url": "https://www.uniprot.org/uniprotkb/B8A489" } ], "reference": [ { "type": "PubMed", "id": "24683187", "url": "https://glygen.org/publication/PubMed/24683187" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8A489", "url": "https://www.uniprot.org/uniprotkb/B8A489" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8A489", "url": "https://www.uniprot.org/uniprotkb/B8A489" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity.", "journal": "J. Immunol.", "date": "2019", "authors": "Levraud Jean-Pierre, Jouneau Luc, Briolat Val\u00e9rie, Laghi Valerio, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "B8A489", "url": "https://www.uniprot.org/uniprotkb/B8A489" } ], "reference": [ { "type": "PubMed", "id": "31732531", "url": "https://glygen.org/publication/PubMed/31732531" } ] } ], "pathway": [ { "id": "dre:558363", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558363", "resource": "KEGG Pathway" }, { "id": "R-DRE-9909505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-9909505", "resource": "Reactome", "description": "Modulation of host responses by IFN-stimulated genes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I5ZTN9-1", "protein_name": "Interferon, alpha-inducible protein 27", "gene_name": "Ifi27", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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Invest. Dermatol.", "date": "2013", "authors": "de la Garza Gabriel, Schleiffarth Jack Robert, Dunnwald Martine, Mankad Anuj, Weirather Jason L, Bonde Gregory, Butcher Stephen, Mansour Tamer A, Kousa Youssef A, Fukazawa Cindy F, Houston Douglas W, Manak J Robert, Schutte Brian C, Wagner Daniel S, Cornell Robert A", "evidence": [ { "database": "UniProtKB", "id": "B8A4A8", "url": "https://www.uniprot.org/uniprotkb/B8A4A8" } ], "reference": [ { "type": "PubMed", "id": "22931925", "url": "https://glygen.org/publication/PubMed/22931925" } ] }, { "title": "Genome-wide identification, characterization, and expression analysis of lineage-specific genes within zebrafish.", "journal": "BMC Genomics", "date": "2013", "authors": "Yang Liandong, Zou Ming, Fu Beide, He Shunping", "evidence": [ { "database": "UniProtKB", "id": "B8A4A8", "url": "https://www.uniprot.org/uniprotkb/B8A4A8" } ], "reference": [ { "type": "PubMed", "id": "23368736", "url": "https://glygen.org/publication/PubMed/23368736" } ] }, { 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This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon. 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{ "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 153, "end_pos": 226, "start_aa": "Phe", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 138, "end_pos": 140 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { 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NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_687135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687135" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A4H3", "url": "https://www.uniprot.org/uniprotkb/B8A4H3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "knop1", "url": "https://www.uniprot.org/uniprotkb/B8A4H3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-76", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-76", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077721", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077721", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "558776", "url": "https://www.ncbi.nlm.nih.gov/gene/558776", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028124", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028124", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:558776", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558776", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WFCEARD", "url": "https://omabrowser.org/oma/group/WFCEARD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8A4H3", "url": "https://www.orthodb.org/?gene=B8A4H3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22426", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22426", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22426:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22426:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15477", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15477", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_687135", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_687135", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8A4H3", "url": "https://www.uniprot.org/uniprotkb/B8A4H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A4H3-1", "url": "https://www.uniprot.org/uniprotkb/B8A4H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-76", "url": "https://zfin.org/ZDB-GENE-090313-76", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAVGRLAKEKKKKIKVKEEEENTDSVKCHDVSVQTAIKQELLDVNDGGEKKKKKKKKLKQELDANNSLVESCDVSVQTTVKTEQIDTNNSVAPEKTKKKKKKIKEEEQIQEEAHIVSKKKKVKKDEAVEGIKKKKKKKKETEVKEEEEEADLGPAVETVNDKKKKRKRKLEEDIIKQELNAEVEDGVIKKKKRKKDVDECVEVEHKVKKKKKKQSVVEEAPENISSNEKPEKKSKKKKKKLESKSLPHANEDNSSDKKMKKKKKLESKSLPDANGENSSDKKMKKKKKNKGKTEADDDVEEKPERTDNNNKSSGKNTNKTLKADPEEYFRKTASRANDVVFLSAKPGNQDEISIDQARRLALQKEIDKESQPKPAFGQWGTASFDSSDRQAKFLRLMGGFKKSTQTGNESAGRLNMAMGKEGQQTLQQGLLGEFERAQNRHMDFRNKGAGLGFSAPSNKKFAIDTNARNSIRFDD", "length": 475, "header": "tr|B8A4H3-1|B8A4H3_DANRE Isoform 1 of Lysine-rich nucleolar protein 1 OS=Danio rerio OX=7955 GN=knop1 PE=4 SV=1 CANONICAL=B8A4H3-1" }, "isoforms": [ { "isoform_ac": "B8A4H3-1", "url": "https://www.uniprot.org/uniprotkb/B8A4H3/entry#B8A4H3-1", "sequence": { "sequence": "MAVGRLAKEKKKKIKVKEEEENTDSVKCHDVSVQTAIKQELLDVNDGGEKKKKKKKKLKQELDANNSLVESCDVSVQTTVKTEQIDTNNSVAPEKTKKKKKKIKEEEQIQEEAHIVSKKKKVKKDEAVEGIKKKKKKKKETEVKEEEEEADLGPAVETVNDKKKKRKRKLEEDIIKQELNAEVEDGVIKKKKRKKDVDECVEVEHKVKKKKKKQSVVEEAPENISSNEKPEKKSKKKKKKLESKSLPHANEDNSSDKKMKKKKKLESKSLPDANGENSSDKKMKKKKKNKGKTEADDDVEEKPERTDNNNKSSGKNTNKTLKADPEEYFRKTASRANDVVFLSAKPGNQDEISIDQARRLALQKEIDKESQPKPAFGQWGTASFDSSDRQAKFLRLMGGFKKSTQTGNESAGRLNMAMGKEGQQTLQQGLLGEFERAQNRHMDFRNKGAGLGFSAPSNKKFAIDTNARNSIRFDD", "length": 475, "header": "tr|B8A4H3-1|B8A4H3_DANRE Isoform 1 of Lysine-rich nucleolar protein 1 OS=Danio rerio OX=7955 GN=knop1 PE=4 SV=1 CANONICAL=B8A4H3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:558776", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:558776", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A4T7-1", "protein_name": "Lysine rich nucleolar protein 1", "gene_name": "KNOP1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MITKTHKGDLGLGLPEKKKKKKKVVPEPETPYLVLNSDSYFTEACPTKAISSLKNVVHGQALEVPPVKKKKKKKGHSAVCEEPLKPEPKLHAGRTESSPGPRKQVLLPSESLRGERKKRKSTSPCARVRTSPDPRQGEEVTRVGKKLKKHKKEKKAQEATAFSAEDPWLCEAGDASYMCSVGKDGEERAALGQKRKQGSPEEHKVKTKKRKKIRQKGDSPLEHPKLSRSEESCPKKGSKKKPVRDEAPEYIPIGDGPKTPAKKKLKSKKKAEPTDTEKPALKRKKKKKRQESRGAEESWEEEPDTDLEVVLEKKGNMDEAHIDQVRRKALQEEIDRESGKTEAPDTKKCQQGTQFGQWDTAGFENEEQKLKFLKLMGGFKNLSASLGRAPAAAGRPSMALSKQAADALQQNLQRDYDRALSWKHSRGAGLGFSPAPDKIFYIDRNASKSVKFGD", "length": 454 }, "evidence": [ { "id": "B8A4H3", "url": "https://omabrowser.org/oma/group/B8A4H3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8I6AUQ0-1", "protein_name": "Lysine-rich nucleolar protein 1", "gene_name": "Knop1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDAVSTATQGAAKLRPGRRTISRGRARNSKLTSGSRLRGCSRGDAWPANRPVMVNKTQKEDLGPRLPEKKKKKKKKKKVANVSEPETQYSVLNNNDYFIDVSPPRATSPFNNVGEVQVPEMSLGKRKKKKKSCSTHLDEYLGKDEPTWTRQIKSPSPRRQVLEQSAEGLIREKKKKRRKSLSKVASQGSGLKTSPDSKHAKEVSKAGRKPKKHRKEKKLPDMEAFPPQDSWIPEAGDALHSCLEGAEAEEQAALGHKRKQGSPRDHSMKKKKKKKTHQEGDILPVNSKISMENSLKKGSKKSVRSEALDFIPIDSLKAPGKKKVKSKKKVEQPVGEGLAVKRKKKKRRKESGVKEDPWQEEKEESDTDLEVVLEKKGNMDEACIDQVRRKALQEEIDRESGKTEVSEPKKWTGTQFGQWDTAGFENEEQKLKFLKLMGGFKHLSPSFNRPPSMTVRSNMALDKKSSDTLQQSLQQDYDRAMSWKYSRGAGLGFNSEARKVFYIDRNASKSIKLQD", "length": 515 }, "evidence": [ { "id": "MGI:1913606", "url": "https://alliancegenome.org/gene/MGI:1913606#orthology", "database": "AGR" }, { "id": "HGNC:34404", "url": "https://alliancegenome.org/gene/HGNC:34404#orthology", "database": "AGR" }, { "id": "B8A4H3", "url": "https://omabrowser.org/oma/group/B8A4H3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A5D7J3-1", "protein_name": "Lysine-rich nucleolar protein 1", "gene_name": "KNOP1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MITKAHKGEVGLGLPEKKKKKKKVVKEPKTQYSVLNSDNYFAEVCPRATPPLKGVIQEQAPRMPLVKKKKKKKGHSTICEEHLEPEITLRAGRTERSHSPRTQALGLSKSLSAEKRKSMSPGSRVKTSPDPRQDEEVTRVGKKLKKHKKEKKAKEATAFSGRDPWFCEAGNTVYTHSVGKDGVREQAALGQKQKQGSPREHSVKMKKKKKIHWEGDPPLGHPECSWSLESSPTKGSKKKPVRVEAPEYIPIGDGSRASVKKKVKSKKRVEQADTEEPALKRKKKKKKRQQSEVAEEPWEEEPDTDLEVVLEKKGNMDEAHIDQVRRKALQEEIDRESGKTEAYDTKKWTGTQFGQWDTAGFENEEQKLKFLKLMGGFKNLPPSFSRPSPTVARPSMALSKKAADTLQRNLQQDYDRALSWKYSRGAGLGFSTAPAKVFYIDRNASKSIKFED", "length": 452 }, "evidence": [ { "id": "B8A4H3", "url": "https://omabrowser.org/oma/group/B8A4H3/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q1ED39-1", "protein_name": "Lysine-rich nucleolar protein 1", "gene_name": "KNOP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MITKTHKVDLGLPEKKKKKKVVKEPETRYSVLNNDDYFADVSPLRATSPSKSVAHGQAPEMPLVKKKKKKKKGVSTLCEEHVEPETTLPARRTEKSPSLRKQVFGHLEFLSGEKKNKKSPLAMSHASGVKTSPDPRQGEEETRVGKKLKKHKKEKKGAQDPTAFSVQDPWFCEAREARDVGDTCSVGKKDEEQAALGQKRKRKSPREHNGKVKKKKKIHQEGDALPGHSKPSRSMESSPRKGSKKKPVKVEAPEYIPISDDPKASAKKKMKSKKKVEQPVIEEPALKRKKKKKRKESGVAGDPWKEETDTDLEVVLEKKGNMDEAHIDQVRRKALQEEIDRESGKTEASETRKWTGTQFGQWDTAGFENEDQKLKFLRLMGGFKNLSPSFSRPASTIARPNMALGKKAADSLQQNLQRDYDRAMSWKYSRGAGLGFSTAPNKIFYIDRNASKSVKLED", "length": 458 }, "evidence": [ { "id": "MGI:1913606", "url": "https://alliancegenome.org/gene/MGI:1913606#orthology", "database": "AGR" }, { "id": "HGNC:34404", "url": "https://alliancegenome.org/gene/HGNC:34404#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-76", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-76#orthology", "database": "AGR" }, { "id": "B8A4H3", "url": "https://omabrowser.org/oma/group/B8A4H3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9Z2Q2-1", "protein_name": "Lysine-rich nucleolar protein 1", "gene_name": "Knop1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVSKTQKADLGPQLPEKKKKKKKKKRVVANVSEPETQYSVLNSNDYFIDASPPRATSPSNNVDEVQIPEISLSKRKKKKKSCSTHLEECLGAEPTRARQKKSPSPRRQALEQSAEGLIREKKKKRRKSLSKAASQGSGLKTSPDPKHAKEVSKAGRKSKKQRKEKKVPDTEALPPQDAWLYEAGDSLHSCLEGAEAEEQAALGQKRKQGSPRDHNMKKKKKTHQEGDILLVNSRVSVENSLKKGSKKSVKSEALEFVPIDSPKAPGKKKVKSKKKVEQPVGEGLAVKRKKKKKKRKENGVKEDPWQEEKEESDTDLEVVLEKKGNMDETCIDQVRRKALQEEIDRESGKTEASEPKKWTVGLSVKTEASEPKKWTGTQFGQWDTAGFENEEQKLKFLKLMGGFKHLSPSFSRPPSMTIRSNMALDKKSSEMLQQSLQQDYDRAMSWKYSHGAGLGFNSEARKVFYIDRNASKSIKLQD", "length": 478 }, "evidence": [ { "id": "MGI:1913606", "url": "https://alliancegenome.org/gene/MGI:1913606#orthology", "database": "AGR" }, { "id": "HGNC:34404", "url": "https://alliancegenome.org/gene/HGNC:34404#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-76", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-76#orthology", "database": "AGR" }, { "id": "B8A4H3", "url": "https://omabrowser.org/oma/group/B8A4H3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 223, "end_pos": 225, "annotation": "n_glycosylation_sequon" }, { "start_pos": 253, "end_pos": 255, "annotation": "n_glycosylation_sequon" }, { "start_pos": 277, "end_pos": 279, "annotation": "n_glycosylation_sequon" }, { "start_pos": 310, "end_pos": 312, "annotation": "n_glycosylation_sequon" }, { "start_pos": 318, "end_pos": 320, "annotation": "n_glycosylation_sequon" }, { "start_pos": 408, "end_pos": 410, "annotation": "n_glycosylation_sequon" }, { "start_pos": 65, "end_pos": 67, "annotation": "n_glycosylation_sequon" }, { "start_pos": 88, "end_pos": 90, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8A4H3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4H3" }, { "id": "PF15477", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15477" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Small acidic protein-like", "eco_id": "ECO_0000259", "start_pos": 379, "end_pos": 452, "start_aa": "Trp", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 223, "end_pos": 225 }, { "start_pos": 253, "end_pos": 255 }, { "start_pos": 277, "end_pos": 279 }, { "start_pos": 310, "end_pos": 312 }, { "start_pos": 318, "end_pos": 320 }, { "start_pos": 408, "end_pos": 410 }, { "start_pos": 65, "end_pos": 67 }, { "start_pos": 88, "end_pos": 90 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B8A4H5-1", "uniprot_ac": "B8A4H5", "uniprot_id": "B8A4H5_DANRE", "mass": { "chemical_mass": 21571.0, "monoisotopic_mass": 21571.0 }, "refseq": { "ac": "NP_001139039", "name": "exosome complex component CSL4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139039" }, "gene_names": [ { "name": "exosc1", "type": "recommended", "evidence": [ { "id": "B8A4H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4H5" } ] }, { "name": "exosc1", "type": "synonym", "evidence": [ { "id": "NP_001139039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139039" } ] } ], "protein_names": [ { "name": "Exosome complex component CSL4", "type": "recommended", "evidence": [ { "id": "B8A4H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4H5/entry#names_and_taxonomy" } ] }, { "name": "Exosome component 1", "type": "synonym", "evidence": [ { "id": "B8A4H5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4H5/entry#names_and_taxonomy" } ] }, { "name": "exosome complex component CSL4", "type": "synonym", "evidence": [ { "id": "NP_001139039", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139039" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BQ284256.1, SRR26395017.1367235.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505375, SAMEA3505377 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000001.1. On Mar 5, 2009 this sequence version replaced XP_687222.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001139039", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139039" } ] } ], "disease": [ { "disease_id": "DOID:0112331", "recommended_name": { "id": "DOID:0112331", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112331", "name": "pontocerebellar hypoplasia type 1F", "description": "A pontocerebellar hypoplasia type 1 characterized by hypotonia, global developmental delay, poor overall growth, and dysmorphic facial features that has_material_basis_in homozygous or compound heterozygous mutation in the EXOSC1 gene on chromosome 10q24.1." }, "synonyms": [ { "id": "DOID:0112331", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0112331", "name": "PCH1F", "description": "" }, { "id": "MONDO:0030261", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0030261", "name": "pontocerebellar hypoplasia, 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8A4L8-1", "uniprot_ac": "B8A4L8", "uniprot_id": "B8A4L8_DANRE", "mass": { "chemical_mass": 41335.0, "monoisotopic_mass": 41335.0 }, "refseq": { "ac": "NP_001161430", "name": "WD repeat-containing protein 89", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161430" }, "gene_names": [ { "name": "wdr89", "type": "recommended", "evidence": [ { "id": "B8A4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4L8" } ] }, { "name": "si:ch211-188i4.2", "type": "synonym", "evidence": [ { "id": "NP_001161430", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161430" }, { "id": "B8A4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4L8" } ] }, { "name": "wdr89", "type": "synonym", "evidence": [ { "id": "NP_001161430", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161430" } ] } ], "protein_names": [ { "name": "WD repeat-containing protein 89", "type": "recommended", "evidence": [ { "id": "B8A4L8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4L8/entry#names_and_taxonomy" } ] }, { "name": "WD repeat-containing protein 89", "type": "synonym", "evidence": [ { "id": "NP_001161430", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161430" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR26395014.283759.1, GFIL01043331.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505376 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On or before Jun 27, 2025 this sequence version replaced XP_073775264.1, XP_001923910.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001161430", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161430" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A4L8", "url": "https://www.uniprot.org/uniprotkb/B8A4L8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "wdr89", "url": "https://www.uniprot.org/uniprotkb/B8A4L8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090319-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090319-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077265", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077265", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100148281", "url": "https://www.ncbi.nlm.nih.gov/gene/100148281", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001680", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001680", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR015943", "url": "https://www.ebi.ac.uk/interpro/entry/IPR015943", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019775", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019775", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036322", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036322", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039328", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039328", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100148281", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148281", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PLGCEYV", "url": "https://omabrowser.org/oma/group/PLGCEYV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8A4L8", "url": "https://www.orthodb.org/?gene=B8A4L8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22889", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22889", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22889:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22889:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00400", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00400", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001161430", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001161430", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58GZU4", "url": "https://www.uniprot.org/uniprotkb/A0AC58GZU4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GZU4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GZU4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GZV9", "url": "https://www.uniprot.org/uniprotkb/A0AC58GZV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GZV9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GZV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A4L8", "url": "https://www.uniprot.org/uniprotkb/B8A4L8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A4L8-1", "url": "https://www.uniprot.org/uniprotkb/B8A4L8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090319-3", "url": "https://zfin.org/ZDB-GENE-090319-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDALEDTFRTLAIARRLQPSEATYILDVSLAASDVLAVCCSNHSVHLHNRETLHQVGQFQGHTAPVCGVRFSHMSPHLLFSGSADGTIRSWDIRRPDSDSVQVFRSDPTHSYCSFDVSCTDRVLCAGTEQVEEDSFLVFWDARMVQDRGPLGVYSESHSDDVTAVKFHPQQADRLASGGTDGLVNVFDLSLGGEDDALVTTCNCNSSASSLCWTGKDLDRLLCLTHDEGLHLWDVARPDSDDTLTLLSSADARPLVQLPDGVSLEYFIGGTWLPDEERTLLVGGSNQGELHLLDCSGSGLRLIKSLKGGHSATVRCFQWDAIGRSLVTGGEDGQLLQWKAGAEEISVGKKESLKSISSMQLKTKAHRKQTTKTDWSKVA", "length": 379, "header": "tr|B8A4L8-1|B8A4L8_DANRE Isoform 1 of WD repeat-containing protein 89 OS=Danio rerio OX=7955 GN=wdr89 PE=4 SV=1 CANONICAL=B8A4L8-1" }, "isoforms": [ { "isoform_ac": "A0AC58GZU4-1", "url": "https://www.uniprot.org/uniprotkb/B8A4L8/entry#A0AC58GZU4-1", "sequence": { "sequence": "MDALEDTFRTLAIARRLQPSEATYILDVSLAASDVLAVCCSNHSVHLHNRETLHQVFRSDPTHSYCSFDVSCTDRVLCAGTEQVEEDSFLVFWDARMVQDRGPLGVYSESHSDDVTAVKFHPQQADRLASGGTDGLVNVFDLSLGGEDDALVTTCNCNSSASSLCWTGKDLDRLLCLTHDEGLHLWDVARPDSDDTLTLLSSADARPLVQLPDGVSLEYFIGGTWLPDEERTLLVGGSNQGELHLLDCSGSGLRLIKSLKGGHSATVRCFQWDAIGRSLVTGGEDGQLLQWKAGAEEISVGKKESLKSISSMQLKTKAHRKQTTKTDWSKVA", "length": 332, "header": "tr|A0AC58GZU4-1|A0AC58GZU4_DANRE Computationally mapped isoform of WD repeat-containing protein 89 OS=Danio rerio OX=7955 GN=wdr89 PE=4 SV=1 CANONICAL=B8A4L8-1" }, "locus": {} }, { "isoform_ac": "A0AC58GZV9-1", "url": "https://www.uniprot.org/uniprotkb/B8A4L8/entry#A0AC58GZV9-1", "sequence": { "sequence": "MLLRTPSGPSPSPEDCSLARPHIFWTFLLQHQMFWPCAAPITLCISTTERRSISDPTHSYCSFDVSCTDRVLCAGTEQVEEDSFLVFWDARMVQDRGPLGVYSESHSDDVTAVKFHPQQADRLASGGTDGLVNVFDLSLGGEDDALVTTCNCNSSASSLCWTGKDLDRLLCLTHDEGLHLWDVARPDSDDTLTLLSSADARPLVQLPDGVSLEYFIGGTWLPDEERTLLVGGSNQGELHLLDCSGSGLRLIKSLKGGHSATVRCFQWDAIGRSLVTGGEDGQLLQWKAGAEEISVGKKESLKSISSMQLKTKAHRKQTTKTDWSKVA", "length": 327, "header": "tr|A0AC58GZV9-1|A0AC58GZV9_DANRE Computationally mapped isoform of WD repeat-containing protein 89 OS=Danio rerio OX=7955 GN=wdr89 PE=4 SV=1 CANONICAL=B8A4L8-1" }, "locus": {} }, { "isoform_ac": "B8A4L8-1", "url": "https://www.uniprot.org/uniprotkb/B8A4L8/entry#B8A4L8-1", "sequence": { "sequence": "MDALEDTFRTLAIARRLQPSEATYILDVSLAASDVLAVCCSNHSVHLHNRETLHQVGQFQGHTAPVCGVRFSHMSPHLLFSGSADGTIRSWDIRRPDSDSVQVFRSDPTHSYCSFDVSCTDRVLCAGTEQVEEDSFLVFWDARMVQDRGPLGVYSESHSDDVTAVKFHPQQADRLASGGTDGLVNVFDLSLGGEDDALVTTCNCNSSASSLCWTGKDLDRLLCLTHDEGLHLWDVARPDSDDTLTLLSSADARPLVQLPDGVSLEYFIGGTWLPDEERTLLVGGSNQGELHLLDCSGSGLRLIKSLKGGHSATVRCFQWDAIGRSLVTGGEDGQLLQWKAGAEEISVGKKESLKSISSMQLKTKAHRKQTTKTDWSKVA", "length": 379, "header": "tr|B8A4L8-1|B8A4L8_DANRE Isoform 1 of WD repeat-containing protein 89 OS=Danio rerio OX=7955 GN=wdr89 PE=4 SV=1 CANONICAL=B8A4L8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8A4L8", "url": "https://www.uniprot.org/uniprotkb/B8A4L8" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:100148281", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148281", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "P53962-1", "protein_name": "Uncharacterized WD repeat-containing protein YNL035C", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MASYSLVESNSFGSENWCLKLQPSYKHGLLTGLSNGEIRLLDWSTGKSVQKIKASETAINDMKVIGSDFSAGHLVSSASIDAVKVFDIRTNDRIAQIQNEANSPFISLDSRHGLLACGTELQGIDAAVYIYDIRKWDTPLRSLIDSHHDDVTCIKFHPSDVNILLSGSTDGYTNIYDLKQDEEEDALHQVINYASIHSCGWLSPKRIFTLSHMETFAIHELNDKSDELKEPQPLDFGDVREIWNCDYVVDIYPGLIATGKTQENCGELCLLPFKDEKVDTENGIVIPHAHGDEVVRDIFIPAQHSNMLYSCGEDGCVKIWENKQGPLDIPENFWDYSKKMNVLGDDDREGSINLDEPLIIQKESVSTRPRKEKHKKAKKHSMKSRFKPY", "length": 389 }, "evidence": [ { "id": "MGI:1919588", "url": "https://alliancegenome.org/gene/MGI:1919588#orthology", "database": "AGR" }, { "id": "HGNC:20489", "url": "https://alliancegenome.org/gene/HGNC:20489#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q5FVP5-1", "protein_name": "WD repeat-containing protein 89", "gene_name": "Wdr89", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEKIKDQFANLHILRRSSEPKEPTYLLGIDTSKTVPAEKGGLVAVLCSNGSIRIYDKETLNLLREFSGSPGLLNGVRFANSCDNVYSASTDGTVKCWDARLASEKPAQLFKGYPSNIFISFDVNCKDHIICAGAEKVEDDALLVFWDARFTSQDLSTRDPLGAYSETHSDDITQVRFHPSNPNMVVSGSTDGLVNVFDLSVDNEEDALVATCNSVSSVSCIGWCGRDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNIQDVRDVTDVKEGHLDYLIGGLYHENMDRLFVIGGTNLGKIHLLSCTKTGLSHVTSLQGGHAATVRSFCWTVSEDSLLTGGEDAQLLLWKPGAVEKTFTKKDSLKIASSVQQRVRVHSSDSYKKRKQQ", "length": 386 }, "evidence": [ { "id": "MGI:1919588", "url": "https://alliancegenome.org/gene/MGI:1919588#orthology", "database": "AGR" }, { "id": "HGNC:20489", "url": "https://alliancegenome.org/gene/HGNC:20489#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96FK6-1", "protein_name": "WD repeat-containing protein 89", "gene_name": "WDR89", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEKIEEQFANLHIVKCSLGTKEPTYLLGIDTSKTVQAGKENLVAVLCSNGSIRIYDKERLNVLREFSGYPGLLNGVRFANSCDSVYSACTDGTVKCWDARVAREKPVQLFKGYPSNIFISFDINCNDHIICAGTEKVDDDALLVFWDARMNSQNLSTTKDSLGAYSETHSDDVTQVRFHPSNPNMVVSGSSDGLVNVFDINIDNEEDALVTTCNSISSVSCIGWSGKGYKQIYCMTHDEGFYWWDLNHLDTDEPVTRLNIQDVREVVNMKEDALDYLIGGLYHEKTDTLHVIGGTNKGRIHLMNCSMSGLTHVTSLQGGHAATVRSFCWNVQDDSLLTGGEDAQLLLWKPGAIEKTFTKKESMKIASSVHQRVRVHSNDSYKRRKKQ", "length": 387 }, "evidence": [ { "id": "MGI:1919588", "url": "https://alliancegenome.org/gene/MGI:1919588#orthology", "database": "AGR" }, { "id": "HGNC:20489", "url": "https://alliancegenome.org/gene/HGNC:20489#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090319-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090319-3#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D0R9-1", "protein_name": "WD repeat-containing protein 89", "gene_name": "Wdr89", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEKIEDQFASLHIVRRSSEPKEPTYLLGIDTSKTVQADKGGLVAVLCSNGSIRIYDKETLHLLREFGGSPGLLSGVSFANSCDSVYSASTDGTVKCWDARGASEKPVQLFKGYPSCSFISFDVNCKDHVICAGAEKVDEDALLVFWDARFTSQDLSTRDPLGAYSETHSDDITQVRFHPSNPNLVVSGSTDGLVNVFDLSADKEEDALVATCNSVSSVSCIGWCGKDYKQIYCMTHDEGFCWWDLNHLDTDEPITCLNIQDVREITDVKDGHLDYLIGGLYHEKMDRLFVIGGTNTGKIHLLSCTSAGLTHVTSLHGGHAATVRSFCWNVSEDSLLTGGEDAQLLLWKPGAMEKTFTKKDSLKIASSVQQRVRVHSSDSYKKRKQQ", "length": 386 }, "evidence": [ { "id": "MGI:1919588", "url": "https://alliancegenome.org/gene/MGI:1919588#orthology", "database": "AGR" }, { "id": "HGNC:20489", "url": "https://alliancegenome.org/gene/HGNC:20489#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090319-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090319-3#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 42, "end_pos": 44 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": 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"NP_001139045", "name": "coiled-coil domain-containing protein 28B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139045" }, "gene_names": [ { "name": "ccdc28b", "type": "recommended", "evidence": [ { "id": "B8A4M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4M8" } ] }, { "name": "ccdc28b", "type": "synonym", "evidence": [ { "id": "NP_001139045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139045" } ] }, { "name": "si:dkey-71p21.10", "type": "synonym", "evidence": [ { "id": "NP_001139045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139045" }, { "id": "B8A4M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4M8" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 28B", "type": "synonym", "evidence": [ { "id": "B8A4M8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4M8/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 28B", "type": "synonym", "evidence": [ { "id": "NP_001139045", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139045" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01003237.1, GDQH01008469.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505377 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000013.1. On Mar 5, 2009 this sequence version replaced XP_688279.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001139045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139045" } ] }, { "annotation": "Depletion of Ccdc28b results in defective ciliogenesis and causes phenotypes that are characteristic of Bardet-Biedl syndrome and other ciliopathy mutants including hydrocephalus, left-right axis determination defects and renal function impairment.", "evidence": [ { "database": "RefSeq", "id": "NP_001139045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139045" }, { "database": "PubMed", "id": "23015189", "url": "https://glygen.org/publication/PubMed/23015189" } ] }, { "annotation": "Findings implicate CCDC28B in the regulation of mTORC2, and uncover a novel function of SIN1 regulating cilia length that is likely independent of mTOR signaling.", "evidence": [ { "database": "RefSeq", "id": "NP_001139045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139045" }, { "database": 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domain-containing protein 28B OS=Danio rerio OX=7955 GN=ccdc28b PE=4 SV=1 CANONICAL=B8A4M8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Hematopoietic gene expression profile in zebrafish kidney marrow.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2004", "authors": "Song Huai-Dong, Sun Xiao-Jian, Deng Min, Zhang Guo-Wei, Zhou Yi, Wu Xin-Yan, Sheng Yan, Chen Yi, Ruan Zheng, Jiang Chun-Lei, Fan Hui-Yong, Zon Leonard I, Kanki John P, Liu Ting Xi, Look A Thomas, Chen Zhu", "evidence": [ { "database": "UniProtKB", "id": "B8A4M8", "url": "https://www.uniprot.org/uniprotkb/B8A4M8" } ], "reference": [ { "type": "PubMed", "id": "15520368", "url": "https://glygen.org/publication/PubMed/15520368" } ] }, { "title": "Dissection of epistasis in oligogenic Bardet-Biedl syndrome.", "journal": "Nature", "date": "2006", "authors": "Badano JL, Leitch CC, Ansley SJ, May-Simera H, Lawson S, Lewis RA, Beales PL, Dietz HC, Fisher S, Katsanis N", "evidence": [ { "database": "UniProtKB", "id": "B8A4M8", "url": "https://www.uniprot.org/uniprotkb/B8A4M8" } ], "reference": [ { "type": "PubMed", "id": "16327777", "url": "https://glygen.org/publication/PubMed/16327777" } ] }, { "title": "Characterization of CCDC28B reveals its role in ciliogenesis and provides insight to understand its modifier effect on Bardet-Biedl syndrome.", "journal": "Hum. Genet.", "date": "2013", "authors": "Cardenas-Rodriguez M, Osborn DP, Irigoin F, Grana M, Romero H, Beales PL, Badano JL", "evidence": [ { "database": "UniProtKB", "id": "B8A4M8", "url": "https://www.uniprot.org/uniprotkb/B8A4M8" }, { "database": "RefSeq", "id": "NP_001139045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139045" } ], "reference": [ { "type": "PubMed", "id": "23015189", "url": "https://glygen.org/publication/PubMed/23015189" } ] }, { "title": "The Bardet-Biedl syndrome-related protein CCDC28B modulates mTORC2 function and interacts with SIN1 to control cilia length independently of the mTOR complex.", "journal": "Hum. Mol. Genet.", "date": "2013", "authors": "Cardenas-Rodriguez M, Irigoin F, Osborn DP, Gascue C, Katsanis N, Beales PL, Badano JL", "evidence": [ { "database": "UniProtKB", "id": "B8A4M8", "url": "https://www.uniprot.org/uniprotkb/B8A4M8" }, { "database": "RefSeq", "id": "NP_001139045", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139045" } ], "reference": [ { "type": "PubMed", "id": "23727834", "url": "https://glygen.org/publication/PubMed/23727834" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8A4M8", "url": "https://www.uniprot.org/uniprotkb/B8A4M8" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8A4M8", "url": "https://www.uniprot.org/uniprotkb/B8A4M8" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Kinesin 1 regulates cilia length through an interaction with the Bardet-Biedl syndrome related protein CCDC28B.", "journal": "Sci. Rep.", "date": "2018", "authors": "Novas R, Cardenas-Rodriguez M, Lepanto P, Fabregat M, Rodao M, Fariello MI, Ramos M, Davison C, Casanova G, Alfaya L, Lecumberry F, Gonzalez-Sapienza G, Irigoin F, Badano JL", "evidence": [ { "database": "UniProtKB", "id": "B8A4M8", "url": "https://www.uniprot.org/uniprotkb/B8A4M8" } ], "reference": [ { "type": "PubMed", "id": "29445114", "url": "https://glygen.org/publication/PubMed/29445114" } ] } ], "pathway": [ { "id": "dre:559814", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559814", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287A3F9-1", "protein_name": "Coiled-coil domain containing 28B", "gene_name": "CCDC28B", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MEDKKKKRSPKPCLTQPAQAPGTLRRVPVPTSHSGSLALGLPHLPSPKQRAKFKRVGKEKCRPVLAGGGGGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEEEEEEEDGVAEGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENTEPEEPSAV", "length": 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"MFKAPGRDSCVGVCRSNTSGSPAASGPGLRSNKHPMDDKKKKRSPKPCLAQPAQASGTLRRVPVPTSHSGSLALGLPHLPSPKQRTKFKRIGKEKCRPVLAGGGGGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEDEDEEDDGVTEGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENAEPEEQPAS", "length": 235 }, "evidence": [ { "id": "B8A4M8", "url": "https://omabrowser.org/oma/group/B8A4M8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "M0R957-1", "protein_name": "Coiled coil domain containing 28B", "gene_name": "Ccdc28b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEDKKKKRSPKPCLTQPAQAPGTLRRVPVPTSHSGSLALGLPHLLSPKQRAKFKRVGKEKCRPVLAGGGGGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEDEEEEEDGVTEGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENAEPEEQPAA", "length": 200 }, "evidence": [ { "id": "HGNC:28163", "url": "https://alliancegenome.org/gene/HGNC:28163#orthology", "database": "AGR" }, { "id": "MGI:1913514", "url": 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"glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8CEG5-1", "protein_name": "Coiled-coil domain-containing protein 28B", "gene_name": "Ccdc28b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEDKKKKRSPKPCLTQPAQAPGTLRRVPVPTSHSGSLALGLPHLPSPKQRAKFKRAGKEKCRPVLAGGGGGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEDEEEEEDGVTEGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENAEPEDQPAA", "length": 200 }, "evidence": [ { "id": "HGNC:28163", "url": "https://alliancegenome.org/gene/HGNC:28163#orthology", "database": "AGR" }, { "id": "MGI:1913514", "url": "https://alliancegenome.org/gene/MGI:1913514#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060208-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060208-3#orthology", "database": "AGR" }, { "id": "B8A4M8", "url": "https://omabrowser.org/oma/group/B8A4M8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BUN5-1", "protein_name": "Coiled-coil domain-containing protein 28B", "gene_name": "CCDC28B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDDKKKKRSPKPCLAQPAQAPGTLRRVPVPTSHSGSLALGLPHLPSPKQRAKFKRVGKEKCRPVLAGGGSGSAGTPLQHSFLTEVTDVYEMEGGLLNLLNDFHSGRLQAFGKECSFEQLEHVREMQEKLARLHFSLDVCGEEEDDEEEEDGVTEGLPEEQKKTMADRNLDQLLSNLEDLSNSIQKLHLAENAEPEEQSAA", "length": 200 }, "evidence": [ { "id": "HGNC:28163", "url": "https://alliancegenome.org/gene/HGNC:28163#orthology", "database": "AGR" }, { "id": "MGI:1913514", "url": "https://alliancegenome.org/gene/MGI:1913514#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060208-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060208-3#orthology", "database": "AGR" }, { "id": "B8A4M8", "url": "https://omabrowser.org/oma/group/B8A4M8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "cilium 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8A4V5-1", "uniprot_ac": "B8A4V5", "uniprot_id": "B8A4V5_DANRE", "mass": { "chemical_mass": 30860.0, "monoisotopic_mass": 30860.0 }, "refseq": { "ac": "XP_001922801", "name": "tumor protein p63-regulated gene 1-like protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922801" }, "gene_names": [ { "name": "tprg1l", "type": "recommended", "evidence": [ { "id": "B8A4V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4V5" } ] }, { "name": "tprg1l", "type": "synonym", "evidence": [ { "id": "XP_001922801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922801" } ] } ], "protein_names": [ { "name": "Tumor protein p63-regulated gene 1-like protein", "type": "synonym", "evidence": [ { "id": "B8A4V5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4V5/entry#names_and_taxonomy" } ] }, { "name": "tumor protein p63-regulated gene 1-like protein", "type": "synonym", "evidence": [ { "id": "XP_001922801", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922801" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133183) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001922801", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922801" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A4V5", "url": "https://www.uniprot.org/uniprotkb/B8A4V5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tprg1l", "url": "https://www.uniprot.org/uniprotkb/B8A4V5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070531-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070531-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000068149", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000068149", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "568867", "url": "https://www.ncbi.nlm.nih.gov/gene/568867", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR022158", "url": "https://www.ebi.ac.uk/interpro/entry/IPR022158", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR034753", "url": "https://www.ebi.ac.uk/interpro/entry/IPR034753", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040242", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040242", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:568867", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568867", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WNPWSSN", "url": "https://omabrowser.org/oma/group/WNPWSSN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8A4V5", "url": "https://www.orthodb.org/?gene=B8A4V5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31108", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31108", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31108:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31108:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12456", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12456", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001922801", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001922801", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8A4V5", "url": "https://www.uniprot.org/uniprotkb/B8A4V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A4V5-1", "url": "https://www.uniprot.org/uniprotkb/B8A4V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070531-2", "url": "https://zfin.org/ZDB-GENE-070531-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLQLNDSVITLDPESPGAAVLLSADCDDGLEVSARAGASVACCSSLQTLTPFHVHNPTMRAKVKDYFVFRPGTIEQAVNDIRTVALPSEDGEVLSVWLLAEVDHWNNEKERLVLITERSLLVCKYDFINLQCQQVIRISLNAVDTISIGEFEFPPKSLNKREGTGIRVQWDKRPRASFMNRWNPWSTDIPYATFTEHPMAHADEKVASLCQLENFKTQLIQAVKKAHKEYPIPGRANGVLILERPLLIETYLGIMSFINNEAKLGYAMTRGKIGF", "length": 275, "header": "tr|B8A4V5-1|B8A4V5_DANRE Isoform 1 of Tumor protein p63-regulated gene 1-like protein OS=Danio rerio OX=7955 GN=tprg1l PE=1 SV=1 CANONICAL=B8A4V5-1" }, "isoforms": [ { "isoform_ac": "B8A4V5-1", "url": "https://www.uniprot.org/uniprotkb/B8A4V5/entry#B8A4V5-1", "sequence": { "sequence": "MLQLNDSVITLDPESPGAAVLLSADCDDGLEVSARAGASVACCSSLQTLTPFHVHNPTMRAKVKDYFVFRPGTIEQAVNDIRTVALPSEDGEVLSVWLLAEVDHWNNEKERLVLITERSLLVCKYDFINLQCQQVIRISLNAVDTISIGEFEFPPKSLNKREGTGIRVQWDKRPRASFMNRWNPWSTDIPYATFTEHPMAHADEKVASLCQLENFKTQLIQAVKKAHKEYPIPGRANGVLILERPLLIETYLGIMSFINNEAKLGYAMTRGKIGF", "length": 275, "header": "tr|B8A4V5-1|B8A4V5_DANRE Isoform 1 of Tumor protein p63-regulated gene 1-like protein OS=Danio rerio OX=7955 GN=tprg1l PE=1 SV=1 CANONICAL=B8A4V5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:568867", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568867", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QRM0-1", "protein_name": "Tumor protein p63 regulated 1 like", "gene_name": "TPRG1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLQLRDSVDSAGTSPTALLAAGEEVGPGGGGSGGGGGGGRPGVGTPLRQTLWPLSIHDPTRRARVKEYFVFRPGTIEQAVEEIRVVVRPVEDGDIQGVWLLTEVDHWNNEKERLVLITDQSLLICKYDFISLQCQQVVRVALSAVDTISYGEFQFPPKSLNKREGVGVRIQWDKQSRPSFISRWNPWSTSVPYTTFTEHPMAGVDEKTASLCQLEDFKALLIQAVKKAQKESPWPGQAGGVLVLERPLLIETYVGLMSFISNEAKLGYSMTRGRIGF", "length": 277 }, "evidence": [ { "id": "B8A4V5", "url": "https://omabrowser.org/oma/group/B8A4V5/", "database": "OMA" } ], "glygen_name": "Pig", 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"tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MLQLRDPEEGGPEDEEEAAGGAAALLVPGGPEPPFSAAPPRQKLRPLNVRTASRAGRLKEYFVFRPGTIEQAVSEIRAVVMPTEDGDVESVWLLTEIDHWNNEKERLVLITDRSLLICKYDFVGLQCQHVTRIALNAIDTISVGEFEFPPKSLNKREGVGIRIQWDKRSRASFINRWNPWSTNVPYATFTEHPMADADEKVASLCLLENFKTQLIQAVKKAHKEWPLPGRANGVLVLERPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 270 }, "evidence": [ { "id": "B8A4V5", "url": "https://omabrowser.org/oma/group/B8A4V5/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F6QRH3-1", "protein_name": "Tumor protein p63 regulated 1 like", "gene_name": "TPRG1L", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLQLRDSVDSAGTSPTALLAAGEEVGPGSGGGGGGGRPGVGTPLRQTLWPLSVHDPTRRARVKEYFVFRPGTIEQAVEEIRVVVRPVEDGDIQGVWLLTEVDHWNNEKERLVLITDQALLICKYDFISLQCQQVVRVALNAVDTISYGEFQFPPKSLNKREGFGIRIQWDKQSRPSFISRWNPWSTSVPYTTFIEHPMAGVDEKTASLCQLDGFKALLIQAVKKAQKESPLPGQEGGVLVLECPLLIETYVGLMSFINNEAKLGYSMTRGKIGF", "length": 274 }, 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"name": "si:ch211-10a23.2", "type": "recommended", "evidence": [ { "id": "B8A4X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4X5" } ] }, { "name": "si:ch211-10a23.2", "type": "synonym", "evidence": [ { "id": "NP_001139237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139237" } ] } ], "protein_names": [ { "name": "Galectin", "type": "recommended", "evidence": [ { "id": "B8A4X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4X5/entry#names_and_taxonomy" } ] }, { "name": "Galectin-related protein A-like", "type": "synonym", "evidence": [ { "id": "NP_001139237", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139237" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC167438.1, GFIL01035405.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000013.1. On Mar 12, 2009 this sequence version replaced XP_696206.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001139237", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139237" } ] }, { "annotation": "Does not bind lactose, and may not bind carbohydrates.", "evidence": [ { "database": "UniProtKB", "id": "B8A4X5", "url": "https://www.uniprot.org/uniprotkb/B8A4X5#function" }, { "database": "UniProtKB", "id": "ARBA00003397", "url": "https://www.uniprot.org/uniprotkb/ARBA00003397#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A4X5", "url": "https://www.uniprot.org/uniprotkb/B8A4X5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-10a23.2", "url": "https://www.uniprot.org/uniprotkb/B8A4X5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-9", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-9", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000060656", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000060656", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00070", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00070", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "567812", "url": "https://www.ncbi.nlm.nih.gov/gene/567812", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567812", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567812", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MKLVIMG", "url": "https://omabrowser.org/oma/group/MKLVIMG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8A4X5", "url": "https://www.orthodb.org/?gene=B8A4X5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11346", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11346", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11346:SF86", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11346:SF86", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00337", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00337", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001139237", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139237", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58H1Q7", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1Q7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H1Q7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H1Q7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A4X5", "url": "https://www.uniprot.org/uniprotkb/B8A4X5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A4X5-1", "url": "https://www.uniprot.org/uniprotkb/B8A4X5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-9", "url": "https://zfin.org/ZDB-GENE-090313-9", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSEKENNRNEEDYVGEIKGGLRPTMRLIVMGIVHKQPKSMVVIVSCQSKGEGDEEIEGDVGLELKVNFPEKAVLRNARLSGKWGSSETALSFFPFAPGEAFKMEIVCEHQQFRILVDGQPLCGFAHRQTQLASLNALRVHGDLQLTKVA", "length": 149, "header": "tr|B8A4X5-1|B8A4X5_DANRE Isoform 1 of Galectin OS=Danio rerio OX=7955 GN=si:ch211-10a23.2 PE=1 SV=1 CANONICAL=B8A4X5-1" }, "isoforms": [ { "isoform_ac": "A0AC58H1Q7-1", "url": "https://www.uniprot.org/uniprotkb/B8A4X5/entry#A0AC58H1Q7-1", "sequence": { "sequence": "MVVIVSCQSKGEGDEEIEGDVGLELKVNFPEKAVLRNARLSGKWGSSETALSFFPFAPGEAFKMEIVCEHQQFRILVDGQPLCGFAHRQTQLASLNALRVHGDLQLTKVA", "length": 110, "header": "tr|A0AC58H1Q7-1|A0AC58H1Q7_DANRE Computationally mapped isoform of Galectin OS=Danio rerio OX=7955 GN=si:ch211-10a23.2 PE=1 SV=1 CANONICAL=B8A4X5-1" }, "locus": {} }, { "isoform_ac": "B8A4X5-1", "url": "https://www.uniprot.org/uniprotkb/B8A4X5/entry#B8A4X5-1", "sequence": { "sequence": "MSEKENNRNEEDYVGEIKGGLRPTMRLIVMGIVHKQPKSMVVIVSCQSKGEGDEEIEGDVGLELKVNFPEKAVLRNARLSGKWGSSETALSFFPFAPGEAFKMEIVCEHQQFRILVDGQPLCGFAHRQTQLASLNALRVHGDLQLTKVA", "length": 149, "header": "tr|B8A4X5-1|B8A4X5_DANRE Isoform 1 of Galectin OS=Danio rerio OX=7955 GN=si:ch211-10a23.2 PE=1 SV=1 CANONICAL=B8A4X5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8A4X5", "url": "https://www.uniprot.org/uniprotkb/B8A4X5" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Galectins in channel catfish, Ictalurus punctatus: Characterization and expression profiling in mucosal tissues.", "journal": "Fish Shellfish Immunol.", "date": "2016", "authors": "Zhou Shun, Zhao Honggang, Thongda Wilawan, Zhang Dongdong, Su Baofeng, Yu Dan, Peatman Eric, Li Chao", "evidence": [ { "database": "UniProtKB", "id": "B8A4X5", "url": "https://www.uniprot.org/uniprotkb/B8A4X5" } ], "reference": [ { "type": "PubMed", "id": "26767746", "url": "https://glygen.org/publication/PubMed/26767746" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8A4X5", "url": "https://www.uniprot.org/uniprotkb/B8A4X5" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "B8A4X5", "url": "https://www.uniprot.org/uniprotkb/B8A4X5" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] } ], "pathway": [ { "id": "dre:567812", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567812", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "B8A4X5", "url": "https://www.uniprot.org/uniprotkb/B8A4X5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8A4X5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A4X5" }, { "id": "PS51304", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51304" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Galectin", "eco_id": "ECO_0000259", "start_pos": 13, "end_pos": 149, "start_aa": "Tyr", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": 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"count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8A5H9-1", "uniprot_ac": "B8A5H9", "uniprot_id": "B8A5H9_DANRE", "mass": { "chemical_mass": 17223.0, "monoisotopic_mass": 17223.0 }, "refseq": { "ac": "NP_001165083", "name": "serglycin precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165083" }, "gene_names": [ { "name": "srgn", "type": "recommended", "evidence": [ { "id": "B8A5H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ] }, { "name": "fk86b08", "type": "synonym", "evidence": [ { "id": "NP_001165083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165083" }, { "id": "B8A5H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ] }, { "name": "si:dkey-226b20.6", "type": "synonym", "evidence": [ { "id": "NP_001165083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165083" }, { "id": "B8A5H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ] }, { "name": "srgn", "type": "synonym", "evidence": [ { "id": "NP_001165083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165083" } ] }, { "name": "wu:fk86b08", "type": "synonym", "evidence": [ { "id": "NP_001165083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165083" }, { "id": "B8A5H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ] } ], "protein_names": [ { "name": "Serglycin precursor", "type": "synonym", "evidence": [ { "id": "B8A5H9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5H9/entry#names_and_taxonomy" } ] }, { "name": "serglycin precursor", "type": "synonym", "evidence": [ { "id": "NP_001165083", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165083" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC159261.1, GDQH01003028.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505388, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Jun 25, 2025 this sequence version replaced NP_001165083.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001165083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165083" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A5H9", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "srgn", "url": "https://www.uniprot.org/uniprotkb/B8A5H9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-7127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7127", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077069", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077069", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "570867", "url": "https://www.ncbi.nlm.nih.gov/gene/570867", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007455", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007455", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570867", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570867", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "NANCVTQ", "url": "https://omabrowser.org/oma/group/NANCVTQ/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8A5H9", "url": "https://www.orthodb.org/?gene=B8A5H9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF04360", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04360", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001165083", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001165083", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8A5H9", "url": "https://www.uniprot.org/uniprotkb/B8A5H9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A5H9-1", "url": "https://www.uniprot.org/uniprotkb/B8A5H9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-7127", "url": "https://zfin.org/ZDB-GENE-030131-7127", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRFYHMITLALAIICLSGHSGLGAPAASTKGNYMWVECKPDGKNANCLTKKGPLIPLDGQRTRLPPSAAKDIVAVSAEEATPDTEDLSGDGSGDSDNFPVLASKKQPWRRDAPEQDIFKNEEEGSTTFSGDIDYSEYVSTQKVNWLSEEDLKEENIIA", "length": 158, "header": "tr|B8A5H9-1|B8A5H9_DANRE Isoform 1 of Serglycin precursor OS=Danio rerio OX=7955 GN=srgn PE=4 SV=1 CANONICAL=B8A5H9-1" }, "isoforms": [ { "isoform_ac": "B8A5H9-1", "url": "https://www.uniprot.org/uniprotkb/B8A5H9/entry#B8A5H9-1", "sequence": { "sequence": "MRFYHMITLALAIICLSGHSGLGAPAASTKGNYMWVECKPDGKNANCLTKKGPLIPLDGQRTRLPPSAAKDIVAVSAEEATPDTEDLSGDGSGDSDNFPVLASKKQPWRRDAPEQDIFKNEEEGSTTFSGDIDYSEYVSTQKVNWLSEEDLKEENIIA", "length": 158, "header": "tr|B8A5H9-1|B8A5H9_DANRE Isoform 1 of Serglycin precursor OS=Danio rerio OX=7955 GN=srgn PE=4 SV=1 CANONICAL=B8A5H9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain.", "journal": "PLoS ONE", "date": "2008", "authors": "Sreenivasan Rajini, Cai Minnie, Bartfai Richard, Wang Xingang, Christoffels Alan, Orban Laszlo", "evidence": [ { "database": "UniProtKB", "id": "B8A5H9", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ], "reference": [ { "type": "PubMed", "id": "18335061", "url": "https://glygen.org/publication/PubMed/18335061" } ] }, { "title": "Discovery and characterization of novel vascular and hematopoietic genes downstream of etsrp in zebrafish.", "journal": "PLoS ONE", "date": "2009", "authors": "Gomez Gustavo A, Veldman Matthew B, Zhao Yan, Burgess Shawn, Lin Shuo", "evidence": [ { "database": "UniProtKB", "id": "B8A5H9", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ], "reference": [ { "type": "PubMed", "id": "19308258", "url": "https://glygen.org/publication/PubMed/19308258" } ] }, { "title": "Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish.", "journal": "PLoS ONE", "date": "2012", "authors": "Gomez Gustavo, Lee Jae-Hyung, Veldman Matthew B, Lu Jing, Xiao Xinshu, Lin Shuo", "evidence": [ { "database": "UniProtKB", "id": "B8A5H9", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ], "reference": [ { "type": "PubMed", "id": "22438865", "url": "https://glygen.org/publication/PubMed/22438865" } ] }, { "title": "TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model.", "journal": "Mol. Cell. Biol.", "date": "2014", "authors": "Ge Liang, Zhang Rui-peng, Wan Feng, Guo Dong-yang, Wang Ping, Xiang Li-xin, Shao Jian-zhong", "evidence": [ { "database": "UniProtKB", "id": "B8A5H9", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ], "reference": [ { "type": "PubMed", "id": "24396069", "url": "https://glygen.org/publication/PubMed/24396069" } ] }, { "title": "Myeloperoxidase-deficient zebrafish show an augmented inflammatory response to challenge with Candida albicans.", "journal": "Fish Shellfish Immunol.", "date": "2015", "authors": "Wang Kun, Fang Xiao, Ma Ning, Lin Qing, Huang Zhibin, Liu Wei, Xu Mengchang, Chen Xiaohui, Zhang Wenqing, Zhang Yiyue", "evidence": [ { "database": "UniProtKB", "id": "B8A5H9", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ], "reference": [ { "type": "PubMed", "id": "25665803", "url": "https://glygen.org/publication/PubMed/25665803" } ] }, { "title": "A switch in pdgfrb+ cell-derived ECM composition prevents inhibitory scarring and promotes axon regeneration in the zebrafish spinal cord.", "journal": "Dev. Cell", "date": "2021", "authors": "Tsata Vasiliki, M\u00f6llmert Stephanie, Schweitzer Christine, Kolb Julia, M\u00f6ckel Conrad, B\u00f6hm Benjamin, Rosso Gonzalo, Lange Christian, Lesche Mathias, Hammer Juliane, Kesavan Gokul, Beis Dimitris, Guck Jochen, Brand Michael, Wehner Daniel", "evidence": [ { "database": "UniProtKB", "id": "B8A5H9", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ], "reference": [ { "type": "PubMed", "id": "33412105", "url": "https://glygen.org/publication/PubMed/33412105" } ] }, { "title": "Runx1 regulates zebrafish neutrophil maturation via synergistic interaction with c-Myb.", "journal": "J. Biol. Chem.", "date": "2021", "authors": "Huang Zhibin, Chen Kemin, Chi Yali, Jin Hao, Li Li, Zhang Wenqing, Xu Jin, Zhang Yiyue", "evidence": [ { "database": "UniProtKB", "id": "B8A5H9", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ], "reference": [ { "type": "PubMed", "id": "33434583", "url": "https://glygen.org/publication/PubMed/33434583" } ] }, { "title": "c-myb is involved in CML progression and is a therapeutic target in the zebrafish CML model.", "journal": "Animal Model Exp Med", "date": "2024", "authors": "Liu W., Yang X., Zhang W., Ye Y., Li F., Huang Z.", "evidence": [ { "database": "UniProtKB", "id": "B8A5H9", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ], "reference": [ { "type": "PubMed", "id": "36300552", "url": "https://glygen.org/publication/PubMed/36300552" } ] }, { "title": "The forkhead transcription factor Foxj1 controls vertebrate olfactory cilia biogenesis and sensory neuron differentiation.", "journal": "PLoS Biol.", "date": "2024", "authors": "Rayamajhi Dheeraj, Ege Mert, Ukhanov Kirill, Ringers Christa, Zhang Yiliu, Jung Inyoung, D'Gama Percival P, Li Summer Shijia, Cosacak Mehmet Ilyas, Kizil Caghan, Park Hae-Chul, Yaksi Emre, Martens Jeffrey R, Brody Steven L, Jurisch-Yaksi Nathalie, Roy Sudipto", "evidence": [ { "database": "UniProtKB", "id": "B8A5H9", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ], "reference": [ { "type": "PubMed", "id": "38271330", "url": "https://glygen.org/publication/PubMed/38271330" } ] }, { "title": "The interaction of Pu.1 and cMyb in zebrafish neutrophil development.", "journal": "Yi Chuan", "date": "2024", "authors": "Hong Jia-Xin, Xu Song-En, Zhang Wen-Qing, Liu Wei", "evidence": [ { "database": "UniProtKB", "id": "B8A5H9", "url": "https://www.uniprot.org/uniprotkb/B8A5H9" } ], "reference": [ { "type": "PubMed", "id": "38632094", "url": "https://glygen.org/publication/PubMed/38632094" } ] } ], "pathway": [ { "id": "dre:570867", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570867", "resource": "KEGG Pathway" }, { "id": "R-DRE-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "P04917-1", "protein_name": "Serglycin", "gene_name": "Srgn", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRQVPVGTRLVLALAFVLVWGSSVQGYPARRARYQWVRCKPDGIFANCIEEKGPRFDLIAEESNVGPPMTDPVLMRGFPNDFFPISDDYSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSGSLADMEWEYQPTDENNIVYFNYGPFDRMLTEQNQEQPGDFII", "length": 179 }, "evidence": [ { "id": "MGI:97756", "url": "https://alliancegenome.org/gene/MGI:97756#orthology", "database": "AGR" }, { "id": "HGNC:9361", "url": "https://alliancegenome.org/gene/HGNC:9361#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P10124-1", "protein_name": "Serglycin", "gene_name": "SRGN", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMQKLLKCSRLVLALALILVLESSVQGYPTRRARYQWVRCNPDSNSANCLEEKGPMFELLPGESNKIPRLRTDLFPKTRIQDLNRIFPLSEDYSGSGFGSGSGSGSGSGSGFLTEMEQDYQLVDESDAFHDNLRSLDRNLPSDSQDLGQHGLEEDFML", "length": 158 }, "evidence": [ { "id": "MGI:97756", "url": "https://alliancegenome.org/gene/MGI:97756#orthology", "database": "AGR" }, { "id": "HGNC:9361", "url": "https://alliancegenome.org/gene/HGNC:9361#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7127#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P13609-1", "protein_name": "Serglycin", "gene_name": "Srgn", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQVPVGSRLVLALAFVLVWGSSVQGYPARRARYQWVRCKPNGFFANCIEEKGPQFDLIDESNNIGPPMNNPVLMEGPSKDFISNYDDYGSGSGSGSGSGSGSGSGSGSGFLGDMEWEYQPTDESNIVYFNYKPFDRILTEQNQDQPEDDFII", "length": 152 }, "evidence": [ { "id": "MGI:97756", "url": "https://alliancegenome.org/gene/MGI:97756#orthology", "database": "AGR" }, { "id": "HGNC:9361", "url": "https://alliancegenome.org/gene/HGNC:9361#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-7127", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-7127#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8A5J2-1", "uniprot_ac": "B8A5J2", "uniprot_id": "B8A5J2_DANRE", "mass": { "chemical_mass": 9333.0, "monoisotopic_mass": 9333.0 }, "refseq": { "ac": "NP_001314760", "name": "cytochrome c oxidase assembly factor 6 homolog", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314760" }, "gene_names": [ { "name": "coa6", "type": "recommended", "evidence": [ { "id": "B8A5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5J2" } ] }, { "name": "coa6", "type": "synonym", "evidence": [ { "id": "NP_001314760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314760" } ] }, { "name": "si:ch211-258f14.5", "type": "synonym", "evidence": [ { "id": "NP_001314760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314760" }, { "id": "B8A5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5J2" } ] } ], "protein_names": [ { "name": "Cytochrome c oxidase assembly factor 6 homolog", "type": "synonym", "evidence": [ { "id": "B8A5J2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5J2/entry#names_and_taxonomy" } ] }, { "name": "cytochrome c oxidase assembly factor 6 homolog", "type": "synonym", "evidence": [ { "id": "NP_001314760", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314760" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH560657.1, GDQH01023029.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505374, SAMEA3505382 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1, EH544899.1 and EH477105.1. On May 26, 2016 this sequence version replaced XP_001923280.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001314760", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314760" } ] } ], "disease": [ { "disease_id": "DOID:0050700", "recommended_name": { "id": "DOID:0050700", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050700", "name": "cardiomyopathy", "description": "A heart disease and a myopathy that is characterized by deterioration of the function of the heart muscle." }, "synonyms": [ { "id": "DOID:0050700", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050700", "name": "Cardiomyopathies", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050700", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050700" } ] }, { "disease_id": "DOID:0050713", "recommended_name": { "id": "DOID:0050713", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050713", "name": "COX deficiency, infantile mitochondrial myopathy", "description": "A cytochrome-c oxidase deficiency disease characterized by myotonia, abnormalities of the heart and kidneys, and lactic acidosis." }, "synonyms": [ { "id": "DOID:0050713", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050713", "name": "fatal infantile COX deficiency", "description": "" }, { "id": "DOID:0050713", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050713", "name": "fatal infantile cytochrome C oxidase deficiency", "description": "" }, { "id": "DOID:0050713", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050713", "name": "fatal infantile encephalocardiomyopathy", "description": "" }, { "id": "DOID:0050713", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050713", "name": "cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency", "description": "" }, { "id": "DOID:0050713", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050713", "name": "fatal infantile cardioencephalomyopathy due to cytochrome c oxidase deficiency", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050713", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050713" } ] }, { "disease_id": "DOID:0080360", "recommended_name": { "id": "DOID:0080360", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080360", "name": "mitochondrial complex IV deficiency nuclear type 13", "description": "A COX deficiency, infantile mitochondrial myopathy that has_material_basis_in homozygous or compound heterozygous mutation in the COA6 gene on chromosome 1q42." }, "synonyms": [ { "id": "DOID:0080360", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080360", "name": "fatal infantile cardioencephalomyopathy due to cytochrome c oxidase deficiency 4", "description": "" }, { "id": "DOID:0080360", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0080360", "name": "MC4DN13", "description": "" }, { "id": "MONDO:0014668", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014668", "name": "cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 4", "description": "Any fatal infantile encephalocardiomyopathy in which the cause of the disease is a mutation in the COA6 gene." }, { "id": "MONDO:0014668", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014668", "name": "COA6 fatal infantile encephalocardiomyopathy", "description": "" }, { "id": "MONDO:0014668", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014668", "name": "cardioencephalomyopathy, fatal infantile, due to cytochrome C oxidase deficiency type 4", "description": "" }, { "id": "MONDO:0014668", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014668", "name": "cardioencephalomyopathy, fatal infantile, due to cytochrome c oxidase deficiency 4", "description": "" }, { "id": "MONDO:0014668", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014668", "name": "fatal infantile encephalocardiomyopathy caused by mutation in COA6", "description": "" }, { "id": "MONDO:0014668", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014668", "name": "mitochondrial complex IV deficiency, nuclear type 13", "description": "" }, { "id": "MONDO:0014668", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0014668", "name": "CEMCOX4", "description": "" }, { "id": "MIM:616501", "resource": "MIM", "url": "https://www.omim.org/entry/616501", "name": "Mitochondrial complex IV deficiency, nuclear type 13", "description": "Mitochondrial complex IV deficiency, nuclear type 13" } ], 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"n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8A5K7-1", "uniprot_ac": "B8A5K7", "uniprot_id": "B8A5K7_DANRE", "mass": { "chemical_mass": 25868.0, "monoisotopic_mass": 25868.0 }, "refseq": { "ac": "NP_001108162", "name": "clarin-2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108162" }, "gene_names": [ { "name": "clrn2", "type": "recommended", "evidence": [ { "id": "B8A5K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5K7" } ] }, { "name": "clrn2", "type": "synonym", "evidence": [ { "id": "NP_001108162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108162" } ] }, { "name": "si:dkey-245p14.5", "type": "synonym", "evidence": [ { "id": "NP_001108162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108162" }, { "id": "B8A5K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5K7" } ] } ], "protein_names": [ { "name": "Clarin-2", "type": "synonym", "evidence": [ { "id": "B8A5K7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5K7/entry#names_and_taxonomy" } ] }, { "name": "clarin-2", "type": "synonym", "evidence": [ { "id": "NP_001108162", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108162" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH608675.1, EH591186.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505380, SAMEA3505382 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Feb 21, 2008 this sequence version replaced XP_001336078.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001108162", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108162" } ] } ], "disease": [ { "disease_id": "DOID:0050565", "recommended_name": { "id": "DOID:0050565", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0050565", "name": "autosomal recessive nonsyndromic deafness", "description": "A nonsyndromic deafness characterized by an autosomal recessive inheritance mode." }, "synonyms": [ { "id": "MONDO:0009076", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0009076", "name": "autosomal recessive nonsyndromic hearing loss 1A", "description": "An autosomal recessive disorder caused by mutations in the GJB2 gene, encoding gap junction beta-2 protein. 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"resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019588", "name": "hearing loss, autosomal recessive", "description": "Autosomal recessive form of nonsyndromic deafness." }, { "id": "MONDO:0019588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019588", "name": "hearing loss, autosomal recessive", "description": "" }, { "id": "MONDO:0019588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019588", "name": "autosomal recessive isolated neurosensory deafness type DFNB", "description": "" }, { "id": "MONDO:0019588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019588", "name": "autosomal recessive isolated sensorineural deafness type DFNB", "description": "" }, { "id": "MONDO:0019588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019588", "name": "autosomal recessive non-syndromic neurosensory deafness type DFNB", "description": "" }, { "id": "MONDO:0019588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019588", "name": "autosomal recessive non-syndromic sensorineural deafness type DFNB", "description": "" }, { "id": "MONDO:0019588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019588", "name": "autosomal recessive nonsyndromic deafness", "description": "" }, { "id": "MONDO:0019588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019588", "name": "autosomal recessive nonsyndromic genetic deafness", "description": "" }, { "id": "MONDO:0019588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019588", "name": "deafness, autosomal recessive", "description": "" }, { "id": "MONDO:0019588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019588", "name": "deafness, neurosensory nonsyndromic recessive, DFN", "description": "" }, { "id": "MONDO:0019588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019588", "name": "nonsyndromic deafness, autosomal recessive", "description": "" }, { "id": "MONDO:0019588", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0019588", "name": "nonsyndromic genetic deafness, autosomal recessive", "description": "" }, { "id": "MIM:220290", "resource": "MIM", "url": "https://www.omim.org/entry/220290", "name": "Deafness, autosomal recessive, 1A", "description": "Deafness, autosomal recessive, 1A" } ], "unlinked_id_list": [], "evidence": [ { "id": "0050565", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0050565" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A5K7", "url": "https://www.uniprot.org/uniprotkb/B8A5K7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "clrn2", "url": "https://www.uniprot.org/uniprotkb/B8A5K7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061207-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-64", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000070321", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000070321", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "795807", "url": "https://www.ncbi.nlm.nih.gov/gene/795807", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026748", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026748", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:795807", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795807", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PKWMTGK", "url": "https://omabrowser.org/oma/group/PKWMTGK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8A5K7", "url": "https://www.orthodb.org/?gene=B8A5K7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31548", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31548", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31548:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31548:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF25807", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25807", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001108162", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108162", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8A5K7", "url": "https://www.uniprot.org/uniprotkb/B8A5K7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A5K7-1", "url": "https://www.uniprot.org/uniprotkb/B8A5K7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061207-64", "url": "https://zfin.org/ZDB-GENE-061207-64", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPTLWKQIVFSFASILSIGSVVLLVVALSTERWVTGTTLCQTGVDLVNASRPELEQFTGHIYYGLFQGGKTRRCGLGIRRAKIYIFPKLIKKINSGLHMIIIFFLFTAIGFAVVSLAFCIYNARKVPYQSIKGPFGLYIWNFIAALFSAMGFACFLAAIQCHKLTEHVANYSESLFTLVILEENLGFSFWLVVASAVTHGANILVVASSKIHLPKIQTKKPEEPTATGEDFLY", "length": 233, "header": "tr|B8A5K7-1|B8A5K7_DANRE Isoform 1 of Clarin-2 OS=Danio rerio OX=7955 GN=clrn2 PE=3 SV=1 CANONICAL=B8A5K7-1" }, "isoforms": [ { "isoform_ac": "B8A5K7-1", "url": "https://www.uniprot.org/uniprotkb/B8A5K7/entry#B8A5K7-1", "sequence": { "sequence": "MPTLWKQIVFSFASILSIGSVVLLVVALSTERWVTGTTLCQTGVDLVNASRPELEQFTGHIYYGLFQGGKTRRCGLGIRRAKIYIFPKLIKKINSGLHMIIIFFLFTAIGFAVVSLAFCIYNARKVPYQSIKGPFGLYIWNFIAALFSAMGFACFLAAIQCHKLTEHVANYSESLFTLVILEENLGFSFWLVVASAVTHGANILVVASSKIHLPKIQTKKPEEPTATGEDFLY", "length": 233, "header": "tr|B8A5K7-1|B8A5K7_DANRE Isoform 1 of Clarin-2 OS=Danio rerio OX=7955 GN=clrn2 PE=3 SV=1 CANONICAL=B8A5K7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The novel insight into the outcomes of CRISPR/Cas9 editing intra- and inter-species.", "journal": "Int. J. Biol. Macromol.", "date": "2020", "authors": "Chang Jiasong, Chen Xiaoxu, Zhang Tong, Wang Ruolin, Wang Aoming, Lan Xinhui, Zhou Yuyu, Ma Sanyuan, Xia Qingyou", "evidence": [ { "database": "UniProtKB", "id": "B8A5K7", "url": "https://www.uniprot.org/uniprotkb/B8A5K7" } ], "reference": [ { "type": "PubMed", "id": "32652159", "url": "https://glygen.org/publication/PubMed/32652159" } ] }, { "title": "A biallelic variant in CLRN2 causes non-syndromic hearing loss in humans.", "journal": "Hum. Genet.", "date": "2021", "authors": "Vona B, Mazaheri N, Lin SJ, Dunbar LA, Maroofian R, Azaiez H, Booth KT, Vitry S, Rad A, Ruschendorf F, Varshney P, Fowler B, Beetz C, Alagramam KN, Murphy D, Shariati G, Sedaghat A, Houlden H, Petree C, VijayKumar S, Smith RJH, Haaf T, El-Amraoui A, Bowl MR, Varshney GK, Galehdari H", "evidence": [ { "database": "UniProtKB", "id": "B8A5K7", "url": "https://www.uniprot.org/uniprotkb/B8A5K7" } ], "reference": [ { "type": "PubMed", "id": "33496845", "url": "https://glygen.org/publication/PubMed/33496845" } ] } ], "pathway": [ { "id": "dre:795807", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795807", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0Y997-1", "protein_name": "Clarin 2", "gene_name": "CLRN2", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPGCFKKTLFALASVISFASFILIVVAMGTPKWMTGKILCKTGAELVNATDPELVKFIGEIYYGLFRGGKIRQCGLGGRRSKFSVFPHMVKKLNTGLHVMIIMFLCVAISFSLVSFGFCILNAIKVPYRAIKGPAGICLWNFLAGGFVALAVTGFMAAVKLHRLTERIANFRENVFQFVILEEQFEDCFWICVAGAAAHAVNLLLIAISCINFPKIKTKTEEANVTAEDIMY", "length": 232 }, "evidence": [ { "id": "B8A5K7", "url": "https://omabrowser.org/oma/group/B8A5K7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0PK11-1", "protein_name": "Clarin-2", "gene_name": "CLRN2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPGWFKKAWYGLASLLSFSSFILIIVALVVPHWLSGKILCQTGVDLVNATDRELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVMILLLLFLALALALVSMGFAILNMIQVPYRAVSGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFQFVVVEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKTKIEEATVTAEDILY", "length": 232 }, "evidence": [ { "id": "HGNC:33939", "url": "https://alliancegenome.org/gene/HGNC:33939#orthology", "database": "AGR" }, { "id": "RGD:1591112", "url": "https://alliancegenome.org/gene/RGD:1591112#orthology", "database": "AGR" }, { "id": "MGI:3646230", "url": "https://alliancegenome.org/gene/MGI:3646230#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-64#orthology", "database": "AGR" }, { "id": "B8A5K7", "url": "https://omabrowser.org/oma/group/B8A5K7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B2RVW2-1", "protein_name": "Clarin-2", "gene_name": "Clrn2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPGWFKKVWYGLASLLSFSSFLLIIVALSLPHWLSGKILCQTGVDLVNATDPELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVTILLLLFLALALALVSMGFAILNIIQVPYRAVNGPGGICLWNVLAGGVVALAIGSFMAAVKFHDLTERIANFQERLFQFVVVEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKTKMEEATVTPEDILY", "length": 232 }, "evidence": [ { "id": "HGNC:33939", "url": "https://alliancegenome.org/gene/HGNC:33939#orthology", "database": "AGR" }, { "id": "RGD:1591112", "url": "https://alliancegenome.org/gene/RGD:1591112#orthology", "database": "AGR" }, { "id": "MGI:3646230", "url": "https://alliancegenome.org/gene/MGI:3646230#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-64#orthology", "database": "AGR" }, { "id": "B8A5K7", "url": "https://omabrowser.org/oma/group/B8A5K7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D3ZL71-1", "protein_name": "Clarin 2", "gene_name": "Clrn2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPGWFKKVWYGLASLLSFSSFLLIIVALALPHWLSGKILCQTGVDLVNATDPELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHITILLLLFLALALALVSMGFAILNIIQVPYRAVNGPGGICLWNVLAGGVVALAISSFMAAVKFHDLTERIANFQERLFQFVVVEEQYEESFWICVASASAHAANLVVVAISQIPLPEVKTKMEEATVTPEDILY", "length": 232 }, "evidence": [ { "id": "HGNC:33939", "url": "https://alliancegenome.org/gene/HGNC:33939#orthology", "database": "AGR" }, { "id": "RGD:1591112", "url": "https://alliancegenome.org/gene/RGD:1591112#orthology", "database": "AGR" }, { "id": "MGI:3646230", "url": "https://alliancegenome.org/gene/MGI:3646230#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-64", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-64#orthology", "database": "AGR" }, { "id": "B8A5K7", "url": "https://omabrowser.org/oma/group/B8A5K7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HR09-1", "protein_name": "Clarin-2", "gene_name": "Clrn2", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MPGWFKKVWYGLASLLSFSSFLLIIIALSVPHWLSGKILCQTGVDLVNATDPELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNASLHVTILLLLFLALALALVSMGFAILNIIQVPYRAVNGPGGICLWNILAGGVVALAIGSFMAAVKFHDLTERIANFQERLFQFVVVEEQYEESFWICVASASAHAANLVVVAISQIPLPEIKTKMEEATVTPEDILY", "length": 232 }, "evidence": [ { "id": "B8A5K7", "url": "https://omabrowser.org/oma/group/B8A5K7/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "G5E553-1", "protein_name": "Clarin 2", "gene_name": "CLRN2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MPGWFKKAWYGLASLLSFSSFILIIVALALPHWLSGKILCQTGVDLVNATDPELVKFIGDIYYGLFRGCKVRQCGLGGRQSQFTIFPHLVKELNAGLHVTLLLLLFLALALALVSMGFAILNMIQVPYRAVNGPGGICLWNVLAGGVVALAIASFMTSVKFHDLTERIANFREKLFRFVVVEEQYEESFWICVASASAHATNLVVVAISQIPLPEVQAKIEEATVTAEDILY", "length": 232 }, "evidence": [ { "id": "B8A5K7", "url": "https://omabrowser.org/oma/group/B8A5K7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "I3LUJ9-1", "protein_name": "Clarin 2", "gene_name": "CLRN2", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MPGWFKKVWYGLASLLSFSSFILIVIALVVPHWLSGKILCQTGVDLVNATDPELVKFIGDIYYGLFRGCKVRQCGLGGRRSQFTIFPHLVRELNAGLHVMILLLLFLALALALVSTGFAILNMIQAPYRAVNGPGGICLWNVLAGGVVALAIASFVAAVKFHDLTERIANFQEKLFRFVVVEEQYEESFWICVASASAHATNLVVVAISQIPLPEMKTKIEEVTVTAEDILY", "length": 232 }, "evidence": [ { "id": "B8A5K7", "url": "https://omabrowser.org/oma/group/B8A5K7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B8A5K7", "url": "https://www.uniprot.org/uniprotkb/B8A5K7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "sensory perception of sound", "id": "GO:0007605", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007605", "evidence": [ { "database": "UniProtKB", "id": "B8A5K7", "url": "https://www.uniprot.org/uniprotkb/B8A5K7" } ], "pmid": "" }, { "name": "auditory receptor cell morphogenesis", "id": "GO:0002093", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002093", "evidence": [ { "database": "UniProtKB", "id": "B8A5K7", "url": "https://www.uniprot.org/uniprotkb/B8A5K7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 48, "end_pos": 50, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], 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"count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8A5K8-1", "uniprot_ac": "B8A5K8", "uniprot_id": "B8A5K8_DANRE", "mass": { "chemical_mass": 21201.0, "monoisotopic_mass": 21201.0 }, "refseq": { "ac": "NP_001108320", "name": "exocyst complex component 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108320" }, "gene_names": [ { "name": "exoc1l", "type": "recommended", "evidence": [ { "id": "B8A5K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5K8" } ] }, { "name": "exoc1l", "type": "synonym", "evidence": [ { "id": "NP_001108320", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108320" } ] }, { "name": "im:7157987", "type": "synonym", "evidence": [ { "id": "NP_001108320", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108320" }, { "id": "B8A5K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5K8" } ] }, { "name": "si:dkey-245p14.4", "type": "synonym", "evidence": [ { "id": "NP_001108320", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108320" }, { "id": "B8A5K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5K8" } ] } ], "protein_names": [ { "name": "Exocyst complex component 1-like", "type": "synonym", "evidence": [ { "id": "B8A5K8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A5K8/entry#names_and_taxonomy" } ] }, { "name": "exocyst complex component 1-like", "type": "synonym", "evidence": [ { "id": "NP_001108320", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108320" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CK692959.1, CF998000.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Feb 24, 2008 this sequence version replaced XP_692032.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001108320", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108320" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A5K8", "url": "https://www.uniprot.org/uniprotkb/B8A5K8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "exoc1l", "url": "https://www.uniprot.org/uniprotkb/B8A5K8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061207-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-63", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000070320", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000070320", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd14682", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14682", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "563576", "url": "https://www.ncbi.nlm.nih.gov/gene/563576", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028258", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028258", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:563576", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563576", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EVEICMV", "url": "https://omabrowser.org/oma/group/EVEICMV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8A5K8", "url": "https://www.orthodb.org/?gene=B8A5K8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PF15277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001108320", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001108320", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8A5K8", "url": "https://www.uniprot.org/uniprotkb/B8A5K8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A5K8-1", "url": "https://www.uniprot.org/uniprotkb/B8A5K8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061207-63", "url": "https://zfin.org/ZDB-GENE-061207-63", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSLLREEMDRVLFRPEGQTLKEFIEIEEQQQGRHFLCVSISKDKEAQISVVMCRRVKHSRTKKLQHSGLEDSYERTETWALTDLLILDGRDPDTDDPCFLMHFNSVRPIRAVSCAAKYTLARCLLSLSRKYHHTALKLKNFDWTYIQPTAMYSDRGDCVVLTQVCFYAFNLVCLSMCPVPLA", "length": 183, "header": "tr|B8A5K8-1|B8A5K8_DANRE Isoform 1 of Exocyst complex component 1-like OS=Danio rerio OX=7955 GN=exoc1l PE=4 SV=1 CANONICAL=B8A5K8-1" }, "isoforms": [ { "isoform_ac": "B8A5K8-1", "url": "https://www.uniprot.org/uniprotkb/B8A5K8/entry#B8A5K8-1", "sequence": { "sequence": "MSSLLREEMDRVLFRPEGQTLKEFIEIEEQQQGRHFLCVSISKDKEAQISVVMCRRVKHSRTKKLQHSGLEDSYERTETWALTDLLILDGRDPDTDDPCFLMHFNSVRPIRAVSCAAKYTLARCLLSLSRKYHHTALKLKNFDWTYIQPTAMYSDRGDCVVLTQVCFYAFNLVCLSMCPVPLA", "length": 183, "header": "tr|B8A5K8-1|B8A5K8_DANRE Isoform 1 of Exocyst complex component 1-like OS=Danio rerio OX=7955 GN=exoc1l PE=4 SV=1 CANONICAL=B8A5K8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8A5K8", "url": "https://www.uniprot.org/uniprotkb/B8A5K8" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:563576", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563576", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A061IL39-1", "protein_name": "Exocyst complex component 1-like", "gene_name": "Exoc1l", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSSLVKEDLEKKLFKPLAQNLCEFIEIEFSVQDRYYLCVSVTKTDEVKIIMVKHYRVGLDEKYEVTKKWSLDDLQMIDGKEADTDNPFFDLHFKKVYSLEAYSCASKYSFARTVNRLNHVYLKKDLHIVNFDSTYINDDSIWSSNNKDCLVLMRICFYAFNLVCLSLCPLPL", "length": 172 }, "evidence": [ { "id": "B8A5K8", "url": "https://omabrowser.org/oma/group/B8A5K8/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0A1B0GW35-1", "protein_name": "Exocyst complex component 1-like", "gene_name": "EXOC1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSLVKEDLEKKLFKPLSQNLYEFIEIEFSVQDRYYLCVSVTKKEEVKIVMVKHYRIGLDEKYEVTKKWSLNDLQMIDGKEADTDNPFFDLHFKKVYSLEAYSCASKYAFARTVNKLNHAYLKKDLQIVNFDSTYINDDSIWSSNNKDCLVLMRICFYAFNLVCLSLCPLPL", "length": 172 }, "evidence": [ { "id": "MGI:3647743", "url": "https://alliancegenome.org/gene/MGI:3647743#orthology", "database": "AGR" }, { "id": "HGNC:53433", "url": "https://alliancegenome.org/gene/HGNC:53433#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-63#orthology", "database": "AGR" }, { "id": "B8A5K8", "url": "https://omabrowser.org/oma/group/B8A5K8/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "B9EK06-1", "protein_name": "Exocyst complex component 1-like", "gene_name": "Exoc1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSLVKEDLEKKLFKPLAQNLCEFIEIEVSVQDRYFLCVSVTKTDEVKITMVKHYRVGLDEKYEVTKRWSLSDLRMIDGKEADTDNPFFDLHFKKVYSLEAYSCASKYSFARTVSRLNHVYLKKDLHMVNFDSTYINDDSIWSSNNKDCLVLMRICFYAFNLVCLSLCPLPL", "length": 172 }, "evidence": [ { "id": "MGI:3647743", "url": "https://alliancegenome.org/gene/MGI:3647743#orthology", "database": "AGR" }, { "id": "HGNC:53433", "url": "https://alliancegenome.org/gene/HGNC:53433#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-63#orthology", "database": "AGR" }, { "id": "B8A5K8", "url": "https://omabrowser.org/oma/group/B8A5K8/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3LVM2-1", "protein_name": "Exocyst complex component 1-like", "gene_name": "EXOC1L", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSLVKEDLEKKLFKPLSQNLYEFIEIEFSVQDRYYLCVSVTKNEEVKIIMVKHYRVGLDEKYEVTKKWSLNDLQMIDGKEADTDNPFFDLHFKKVYSLEAYSCASKYAFARTVNKLNHAYLKKDLQIVNFDSTYINDDSIWSSNNKDCLVLMRICFYAFNLVCLSLCPLPL", "length": 172 }, "evidence": [ { "id": "B8A5K8", "url": "https://omabrowser.org/oma/group/B8A5K8/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M0R528-1", "protein_name": "Exocyst complex component 1-like", "gene_name": "Exoc1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSLVKEDLEKRLFKPLAQNLCEFIEIEVSVQDRYYLCVSVTKTDEVKISMVKHYRVGLDEKYEVTKRWSLNDLRMIDGKEADTDNPFFDLHFKKVYSLEAYSCASKYSFARTVSRLNHVYLKKDLHIVNFDSTYINDDSIWSSNNKDCLVLMRICFYAFNLVCLSLCPLPL", "length": 172 }, "evidence": [ { "id": "MGI:3647743", "url": "https://alliancegenome.org/gene/MGI:3647743#orthology", "database": "AGR" }, { "id": "HGNC:53433", "url": "https://alliancegenome.org/gene/HGNC:53433#orthology", "database": "AGR" }, { "id": "B8A5K8", "url": 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"https://www.ncbi.nlm.nih.gov/protein/NP_001082916" } ] }, { "name": "uncharacterized protein LOC100000024", "type": "synonym", "evidence": [ { "id": "NP_001082916", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082916" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588723.864591.1, SRR32588714.25045496.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476760, SAMEA898400 [ECO:0006172] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On or before Feb 11, 2016 this sequence version replaced XP_005156654.1, NP_001082916.1. Sequence Note: This RefSeq record was created from genomic sequence data because no single transcript from the reference strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments, RNA-seq data and orthologous data.", "evidence": [ { "database": "RefSeq", "id": "NP_001082916", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001082916" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A626", "url": "https://www.uniprot.org/uniprotkb/B8A626" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-33c12.12", "url": "https://www.uniprot.org/uniprotkb/B8A626", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081028-30", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081028-30", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000095545", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000095545", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06785", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06785", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100000024", "url": "https://www.ncbi.nlm.nih.gov/gene/100000024", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001940", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001940", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036034", "url": 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"protein_names": [ { "name": "Uncharacterized protein LOC571862 precursor", "type": "synonym", "evidence": [ { "id": "B8A646", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A646/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC571862 precursor", "type": "synonym", "evidence": [ { "id": "NP_001139081", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139081" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CD758830.1, SRR32588722.9186344.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN08196787, SAMN08196788 [ECO:0000348] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000001.1. On Mar 5, 2009 this sequence version replaced XP_700588.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001139081", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139081" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A646", "url": "https://www.uniprot.org/uniprotkb/B8A646" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-9i23.5", "url": "https://www.uniprot.org/uniprotkb/B8A646", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-364", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-364", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092459", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092459", "database": "Bgee", "categories": [ "Gene Expression" ] }, { 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{ "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B8A682-1", "uniprot_ac": "B8A682", "uniprot_id": "B8A682_DANRE", "mass": { "chemical_mass": 73988.0, "monoisotopic_mass": 73988.0 }, "refseq": { "ac": "NP_001189400", "name": "AN1-type zinc finger protein 4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189400" }, "gene_names": [ { "name": "zfand4", "type": "recommended", "evidence": [ { "id": "B8A682", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A682" } ] }, { "name": "si:dkey-194n13.3", "type": "synonym", "evidence": [ { "id": "NP_001189400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189400" }, { "id": "B8A682", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A682" } ] }, { "name": "zfand4", "type": "synonym", "evidence": [ { "id": "NP_001189400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189400" } ] } ], "protein_names": [ { "name": "AN1-type zinc finger protein 4", "type": "synonym", "evidence": [ { "id": "NP_001189400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189400" }, { "id": "B8A682", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A682/entry#names_and_taxonomy" } ] }, { "name": "anubl1", "type": "synonym", "evidence": [ { "id": "NP_001189400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189400" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01044058.1, GDQH01024888.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001189400", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189400" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A682", "url": "https://www.uniprot.org/uniprotkb/B8A682" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zfand4", "url": "https://www.uniprot.org/uniprotkb/B8A682", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090312-102", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-102", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000076703", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000076703", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01802", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01802", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100148477", "url": "https://www.ncbi.nlm.nih.gov/gene/100148477", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000058", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000058", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR000626", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000626", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR019956", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019956", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035896", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035896", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053061", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053061", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100148477", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148477", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ECRCGHN", "url": "https://omabrowser.org/oma/group/ECRCGHN/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8A682", "url": "https://www.orthodb.org/?gene=B8A682", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46728", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46728", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46728:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46728:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00240", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00240", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF01428", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01428", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001189400", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001189400", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8A682", "url": "https://www.uniprot.org/uniprotkb/B8A682", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A682-1", "url": "https://www.uniprot.org/uniprotkb/B8A682-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090312-102", "url": "https://zfin.org/ZDB-GENE-090312-102", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTDKRNPPFFNDDNVGVLHYKLPFSETMELFIETLTGTCFQLRVSPFEQVVSVKAKIQRLEGIPVSQQHLIWNGMELEDEYCLHDYSITEGCTLKLVLAMRGGPVNTRRVTVTDDSVRDISDCLDAGREEMWEKSLPNKQVTFLVYREGDQLNFFRVVDRGDGTLTPVSESLSGASVRNVRAEEEEEQESASSELQTLENSITMGKMKLLKAKMENMNLNKKPKKTAKLKIRPPVGPRPCSGSHGSARHHRMFRVLPQIGHASSTHLPPIGDQQQPVLSTPTAGSAHQPYTSLSSPASSSRAHPSSAASGIYMLQAEEPWDNPVPRKIRLPPKVSRLDMRGPKVMRDCVYPPLSLLSSPGVQDEVDIKNEHLTLTEKTTVIESPKAVPFNLPEPLSLDVSAQRERSLNSLTMPEANAAAPLLSQAVNSNWRLPSQHDLTLTTEPFTPPRHFEFTGSSVHPSPSHALLRTSPSLPISSPSKTTFKVDKHSEVISKSEARDITNLANKATKEPLGSVSNAELLASLAGSGGQETLTSPYALGRLCATAAPLPNNIHLLQEDLLRRISPLQRTAGFTASSSSSGLSSSIKRLGTQTHHLPPVKVSSGVKKKSSKHCFLCGKKTGLATSYECRCGNIFCSIHRYSETHDCTYDYKSAGRRFLQETNPIVSAPKLPKI", "length": 673, "header": "tr|B8A682-1|B8A682_DANRE Isoform 1 of AN1-type zinc finger protein 4 OS=Danio rerio OX=7955 GN=zfand4 PE=4 SV=1 CANONICAL=B8A682-1" }, "isoforms": [ { "isoform_ac": "B8A682-1", "url": "https://www.uniprot.org/uniprotkb/B8A682/entry#B8A682-1", "sequence": { "sequence": "MTDKRNPPFFNDDNVGVLHYKLPFSETMELFIETLTGTCFQLRVSPFEQVVSVKAKIQRLEGIPVSQQHLIWNGMELEDEYCLHDYSITEGCTLKLVLAMRGGPVNTRRVTVTDDSVRDISDCLDAGREEMWEKSLPNKQVTFLVYREGDQLNFFRVVDRGDGTLTPVSESLSGASVRNVRAEEEEEQESASSELQTLENSITMGKMKLLKAKMENMNLNKKPKKTAKLKIRPPVGPRPCSGSHGSARHHRMFRVLPQIGHASSTHLPPIGDQQQPVLSTPTAGSAHQPYTSLSSPASSSRAHPSSAASGIYMLQAEEPWDNPVPRKIRLPPKVSRLDMRGPKVMRDCVYPPLSLLSSPGVQDEVDIKNEHLTLTEKTTVIESPKAVPFNLPEPLSLDVSAQRERSLNSLTMPEANAAAPLLSQAVNSNWRLPSQHDLTLTTEPFTPPRHFEFTGSSVHPSPSHALLRTSPSLPISSPSKTTFKVDKHSEVISKSEARDITNLANKATKEPLGSVSNAELLASLAGSGGQETLTSPYALGRLCATAAPLPNNIHLLQEDLLRRISPLQRTAGFTASSSSSGLSSSIKRLGTQTHHLPPVKVSSGVKKKSSKHCFLCGKKTGLATSYECRCGNIFCSIHRYSETHDCTYDYKSAGRRFLQETNPIVSAPKLPKI", "length": 673, "header": "tr|B8A682-1|B8A682_DANRE Isoform 1 of AN1-type zinc finger protein 4 OS=Danio rerio OX=7955 GN=zfand4 PE=4 SV=1 CANONICAL=B8A682-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100148477", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148477", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3Z3C6-1", "protein_name": "AN1-type zinc finger protein 4", "gene_name": "Zfand4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFKADLGRIGIQLHTTYSRRIRKVKVMDNRKEPPFFNEDNVGPFYFKLPFYDTMELFIETLTGTCFELRVSPFEAVISVKGKIQRLEGIPICQQHLIWNNMELEDDYCLNDYNISEGCTLKLVLAMRGGPISTRKVPVEDPLRELAEYMDSSRDEVWEKTSCNKQVTFLVYREGDQLNFFRVVDRGDGTLTPLSESLSGSVYNLYTDEDEEAEPSPSGQQIIENSITMNKMKLLKAKMENMNLSKKPKKVVKVKPRPPLAPRPTSSSTAAARHRLLRVLPHIGQSCLPSGNAHLPETSRNAGPSPAAQAPADRPVSSLRNELLKDDDNWEINMLSHSTSSIRLLPQLTHIELESDKELADSVLHLGSSLSRRTKHLSGNLLSNNEDDVVLFPRSEECVADELLLPEVGAFAPFAEGTGAEQSSGVEGLGKVTPEFPLTKGDGGLRAAEQPLSHVARVLSSEPGDNAVLNHREPSSHKNRLLSPLLCAAPVSLHNSLVKPQRQSKCFESGNPSASTSQNTLRELDIRTIADSSFSRTARFRGVKVDSPGKRSDIISKVEARDITEMANKASKEPVGCVNNNGFLASLARSASRDSLQSTHGACRLRSSGIGLSTNFQHFQDENIRKSSPQSEPTDFFLSARGIGMSGSNAAAGKRIGESIHHLPPVKAPLQTKKKIMKHCFLCGKKTGLATSFECRCGNNFCASHRYAEAHGCTYDYKSAGRRYLEEANPVVNAPKLPKI", "length": 739 }, "evidence": [ { "id": "MGI:1914742", "url": "https://alliancegenome.org/gene/MGI:1914742#orthology", "database": "AGR" }, { "id": "HGNC:23504", "url": "https://alliancegenome.org/gene/HGNC:23504#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-102", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-102#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "F1SDV0-1", "protein_name": "Zinc finger AN1-type containing 4", "gene_name": "ZFAND4", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFKADLARTGIQLPATYSRGIRKVKIMDNRKDPPFFNEDNVGPFYYKLPFYDTMELFIETLTGTCFELRVSPFEAIIYVKAKIQRLEGIPICQQHLIWNNMELEDDYCLSDYNISEGCTLKLVLAMRGGPINTRRVPMEDPLREMAEYMDSSRDEGWEKTSCNKQVTFLVYREGDQLNFFRVVDRGDGTLTPLSESLSGGSVYNLHADEDEEIEPSPSGQQIIENSITMNKMKLLKAKMENMNLSKKPKKAIKVKPRPPIAPRPSSCSTAAARHRLLRVLPHIGQSCLPSPRNACLHDSTSNAISSLGTLPPADRPISSIASDFLKEDDNWESNTLSHSNSGFKLPPEICHTESESDKELADSVAHLGLSLPRRTKLFSGNFPPNNEDDTVLFSTSEECVTEESLLPEVGSFASCTEGNADEQSSGLEGTRKVNREFLLTNDDKGLKATEQHLKHVARVLSGESVETTVLNNRELSPHKNRLLSPLRCSAPMALHNSLVKPQRRSKCFESGNLQSSASQNVLRSLDVRNITDSSFSRTTRFRAVKVDSPGKRSDIISKVEARDITEMANKASKEPVGCVNNIGFLASLARSASRDSLQSTRGAGRLRTSGTGLSTKLQHFQEESLRKSSPQLEPSEFFLSTRGTGMNGNNTATGKRVGECTHHLPPVKAPIQTKKKTAKHCFLCGKKTGLATSYECRCGNNFCASHRYAETHSCTYDYKSAGRRYLQEANPVVNAPKLPKI", "length": 741 }, "evidence": [ { "id": "B8A682", "url": "https://omabrowser.org/oma/group/B8A682/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "F7EY43-1", "protein_name": "Zinc finger AN1-type containing 4", "gene_name": "Zfand4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMAEQGTKLKHEQRYILPMFKADLGTIGIQLHTTYSRRIRKVKVMDNRKEPPFFNEDNVGPFYFKLPFYDPMELFIETLTGTCFELRVSPFEAVISVKGKIQRLEGIPICQQHLIWNNMELEDDYCLNDYNISEGCTLKLVLAMRGGPISTRKVPVEDPLRELAEYMDSSRDEVWEKTSCNKQVTFLVYREGDQLNFFRVVDRGDGTLTPLSESLSGGSVYNLYTDEDEETEPSPSGQQIIENSITMNKMKLLKAKMENMNLSKKPKKVVKVKPRPPIAPRPSSSSAAAARHRLLRVLPHIGQSCLPSGNAYVPETSRNAGTSSAAQAPADRPMPSLRSELLKDDGNWERNMLSHSTSSIRLLPQLTHLDLENDKELPDSVLHLGSSLPRRTKHLSGNLSSNNEEDVVLFPRSEECVADELLLPEVGPFAPFAEGNGAEQSSGVEGLGKVTPEFPLTKGDGGLRAAEQPLSHMARVLSSDPGDNAVLNHHREPGSHKNRLLSPLLCVAPVSLHNSLVKPQRQSKCFESGNPSASTSQNTLRELDIRTIADSPFSRTARFRGVKVDSPGKRSDVISKVEARDITEMANKASKEPVGCVNNNGFLASLARSASRDSLHSTRGVGRLRSSGIGLSTNFQHFQDENIRKSSPQSEPTDFFLSARGIGMNGSNAAAGKRIGESTHHLPPVKAPLQTKKKVTKHCFLCGKKTGLATSFECRQMWKQLLCISSLCRSSWLHL", "length": 735 }, "evidence": [ { "id": "MGI:1914742", "url": "https://alliancegenome.org/gene/MGI:1914742#orthology", "database": "AGR" }, { "id": "HGNC:23504", "url": "https://alliancegenome.org/gene/HGNC:23504#orthology", "database": "AGR" }, { "id": "B8A682", "url": "https://omabrowser.org/oma/group/B8A682/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3HVM4-1", "protein_name": "AN1-type zinc finger protein 4 isoform X4", "gene_name": "Zfand4", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MRGGPISTRKVPVEDPLRELAEYMDSSRDEVWEKTSCNKQVTFLVYREGDQLNFFRVVDRGDGTLTPLSESLSGGSVYNLYTDEDEEAEPSPSGQQIIENSITMNKMKLLKAKMENMNLSKKPKKVVKVKPRPPVAPRPPSSSTAAARHRLLRVLPHIGQSCLPSPGNAYLPETSRNAGTSSSAAQGPVDRPVSSLRNELLKEDDKWEMNALSHPPGSIRLLPQMAHIELENDKELADSVLHLGSSLPRRTKLLSGNLPSSNEDDVVLFPPSEECVSEELLLPEVGPFAPFAEGNGVEQSSGVEGIGKVTPEFPLTKGDRGLRAAEQPLNHVARVLSSDPIDNAILNHRESSSHKNRLLSPLLCAAPVSLHNSLVKPQRQSKCFESGNPSASTSQNALRELDIRTIADSSFSRTARFRGVKVDSPGKRSDIISKVEARDITEMANKASKEPVGCVNNNGFLASLARSASRDSLQNTRGAGRLRPSGIGLSTNFQHFQDENIRKSSPQSEPTEFFLSARGIGVSGNNAAAGKRVGESTRHLPPVKAPLQAKKKITKHCFLCGKKTGLASSFECRCGNNFCASHRYAETHGCTYDYKGAGRRYLQEANPVVNAPKLPKI", "length": 617 }, "evidence": [ { "id": "B8A682", "url": "https://omabrowser.org/oma/group/B8A682/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q86XD8-1", "protein_name": "AN1-type zinc finger protein 4", "gene_name": "ZFAND4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDNRKEPPFFNDDNMGPFYYRLHFCDTMELFIETLTGTCFELRVSPFETVISVKAKIRRLEGIPICRQHLIWNNMELENDYCLNDYNISEGCTLKLVLAMRGGPINTRRVPTDDPLRKMAEYLDSSRVEVWEKTSCSKQVTFLVYQEGDQLNFFPAVDRGDGTLTPLSDSSKKIDFHLHVLRRKGEHRMSGGSMYNSDTDEDEETEPSSSGQQIIENSITMNKMKLLKAKMKNMNLSKKPKKAVKIKPHPPVAPRPSSGSTAPSRHRLLRVLPNIGQSCSPAFGNAYPPEISRNGISSLATQLSAERYISSITGEFLKEDNSWENNTLSHFSSNVKLPPQIPHLELGNDQELADSVLHLGSSLPRQTKHFLGNLPSSNGNIVLPSEECVTEQSLLPKVGSLASFAEGNADEQSSGLEGACKVNLELLLTNADKGLKAPEQHLKHVAGVLNGESVETSVLNYRELSPHKNRLLSPLRCSAPMSLHNSLVKPERQSKCFEFGKLQPSSSQSLDVQNITDSSFSRTTCFQGVKVDSLGKRSDVISKVEARDITEMTNKASKEPVGCVNNISFLASLAGSTSRNRLQSTRGAGRLQNSGTGLSTNLQHFQEENFRKSSPQLEHTGVFLSTHGVGMNGNNAAAGKSVGECTTHHLPPVKAPLQTKKKTTNHCFLCGKKTGLASSYECRCGNNFCASHRYAETHGCTYDYKSAGRRYLHEANPVVNAPKLPKI", "length": 727 }, "evidence": [ { "id": "MGI:1914742", "url": "https://alliancegenome.org/gene/MGI:1914742#orthology", "database": "AGR" }, { "id": "HGNC:23504", "url": "https://alliancegenome.org/gene/HGNC:23504#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-102", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-102#orthology", "database": "AGR" }, { "id": "B8A682", "url": "https://omabrowser.org/oma/group/B8A682/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B8A682", "url": "https://www.uniprot.org/uniprotkb/B8A682" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8A682", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A682" }, { "id": "PS51039", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51039" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "AN1-type", "eco_id": "ECO_0000259", "start_pos": 607, "end_pos": 654, "start_aa": "Lys", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "B8A682", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A682" }, { "id": "PS50053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ubiquitin-like", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 103, "start_aa": "Met", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], 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The reference sequence was derived from BC154509.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001188285", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188285" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A6A2", "url": "https://www.uniprot.org/uniprotkb/B8A6A2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-228d14.5", "url": "https://www.uniprot.org/uniprotkb/B8A6A2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-252", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-252", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000057440", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000057440", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "796266", "url": "https://www.ncbi.nlm.nih.gov/gene/796266", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019402", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019402", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050911", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050911", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CICFYTI", "url": "https://omabrowser.org/oma/group/CICFYTI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8A6A2", "url": "https://www.orthodb.org/?gene=B8A6A2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21324", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21324", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21324:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21324:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10277", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10277", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001188285", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001188285", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8A6A2", "url": "https://www.uniprot.org/uniprotkb/B8A6A2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A6A2-1", "url": "https://www.uniprot.org/uniprotkb/B8A6A2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-252", "url": "https://zfin.org/ZDB-GENE-090313-252", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MALWIILPVLLCAVSFIGCWTVYGLALSYNHICSLNTWEYRNSCHPNETGNCCTMNNIPTVSASGTNFPENSLFTATISAGSFLFLVFCVFHHAHILDRNSVHSLLSKIALIMGCVVSASAFMAGNCNPAELVLLHYLGAAVSFVFVCLYMIILTSLTTRCMLTGCEQVLYPLRIILTIIQVSATILYGIFFIQEHYFYKQISAVFEWFLCVNLELYELSYSVEFYFFSSSMLSVLLAKKEEEKPLILS", "length": 249, "header": "tr|B8A6A2-1|B8A6A2_DANRE Isoform 1 of Uncharacterized protein LOC796266 precursor OS=Danio rerio OX=7955 GN=si:dkey-228d14.5 PE=3 SV=1 CANONICAL=B8A6A2-1" }, "isoforms": [ { "isoform_ac": "B8A6A2-1", "url": "https://www.uniprot.org/uniprotkb/B8A6A2/entry#B8A6A2-1", "sequence": { "sequence": "MALWIILPVLLCAVSFIGCWTVYGLALSYNHICSLNTWEYRNSCHPNETGNCCTMNNIPTVSASGTNFPENSLFTATISAGSFLFLVFCVFHHAHILDRNSVHSLLSKIALIMGCVVSASAFMAGNCNPAELVLLHYLGAAVSFVFVCLYMIILTSLTTRCMLTGCEQVLYPLRIILTIIQVSATILYGIFFIQEHYFYKQISAVFEWFLCVNLELYELSYSVEFYFFSSSMLSVLLAKKEEEKPLILS", "length": 249, "header": "tr|B8A6A2-1|B8A6A2_DANRE Isoform 1 of Uncharacterized protein LOC796266 precursor OS=Danio rerio OX=7955 GN=si:dkey-228d14.5 PE=3 SV=1 CANONICAL=B8A6A2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. 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This record is derived from a genomic sequence (NC_133188) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005157097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157097" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A6I2", "url": "https://www.uniprot.org/uniprotkb/B8A6I2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zfyve21", "url": "https://www.uniprot.org/uniprotkb/B8A6I2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-1296", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-1296", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000027887", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000027887", "database": "Bgee", "categories": [ "Gene 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"InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR038632", "url": "https://www.ebi.ac.uk/interpro/entry/IPR038632", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052113", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052113", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100004144", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004144", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HCEIEIA", "url": "https://omabrowser.org/oma/group/HCEIEIA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8A6I1", "url": "https://www.orthodb.org/?gene=B8A6I1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "B8A6I2", "url": "https://www.orthodb.org/?gene=B8A6I2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR39490", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39490", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39490:SF8", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39490:SF8", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01363", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01363", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16696", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16696", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005157097", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157097", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8A6I1", "url": "https://www.uniprot.org/uniprotkb/B8A6I1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A6I1-1", "url": "https://www.uniprot.org/uniprotkb/B8A6I1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A6I2", "url": "https://www.uniprot.org/uniprotkb/B8A6I2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A6I2-1", "url": "https://www.uniprot.org/uniprotkb/B8A6I2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-1296", "url": "https://zfin.org/ZDB-GENE-030131-1296", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSAVPDGKKLVRSPSGLRMVPENGAFNSPFTLDEPQWVPDKECPRCMQCDTKFDFITRKHHCRRCGRCFCDKCCSQKVALPRMCFVDPVRQCAECSLISQKEVEFYDKQLKVLTAGGTFVVKVGSSEKSETMVCRLSNNHRYLFLDGNSHFEVELSRISSMQVLTEGSTPGEKDICSYTSLLDNQISEGGTLRASGMVLQYKPPGSLDLQQLNMDTADDKRIASAWLAAMHKAAKLLYESKDQ", "length": 243, "header": "tr|B8A6I2-1|B8A6I2_DANRE Isoform 1 of Zinc finger FYVE domain-containing protein 21 isoform X1 OS=Danio rerio OX=7955 GN=zfyve21 PE=4 SV=1 CANONICAL=B8A6I2-1" }, "isoforms": [ { "isoform_ac": "B8A6I1-1", "url": "https://www.uniprot.org/uniprotkb/B8A6I2/entry#B8A6I1-1", "sequence": { "sequence": "MSAVPDGKKLVRSPSGLRMVPENGAFNSPFTLDEPQWVPDKECPRCMQCDTKFDFITRKHHCRRCGRCFCDKCCSQKVALPRMCFVDPVRQCAECSLISQKEVEFYDKQLKVLTAGGTFVVKVGSSEKSETMVCRLSNNHRYLFLDGNSHFEVELSRISSMQVLTEGSTPGGGTLRASGMVLQYKPPGSLDLQQLNMDTADDKRIASAWLAAMHKAAKLLYESKDQ", "length": 226, "header": "tr|B8A6I1-1|B8A6I2_DANRE Computationally mapped isoform of Zinc finger FYVE domain-containing protein 21 isoform X1 OS=Danio rerio OX=7955 GN=zfyve21 PE=4 SV=1 CANONICAL=B8A6I2-1" }, "locus": {} }, { "isoform_ac": "B8A6I2-1", "url": "https://www.uniprot.org/uniprotkb/B8A6I2/entry#B8A6I2-1", "sequence": { "sequence": "MSAVPDGKKLVRSPSGLRMVPENGAFNSPFTLDEPQWVPDKECPRCMQCDTKFDFITRKHHCRRCGRCFCDKCCSQKVALPRMCFVDPVRQCAECSLISQKEVEFYDKQLKVLTAGGTFVVKVGSSEKSETMVCRLSNNHRYLFLDGNSHFEVELSRISSMQVLTEGSTPGEKDICSYTSLLDNQISEGGTLRASGMVLQYKPPGSLDLQQLNMDTADDKRIASAWLAAMHKAAKLLYESKDQ", "length": 243, "header": "tr|B8A6I2-1|B8A6I2_DANRE Isoform 1 of Zinc finger FYVE domain-containing protein 21 isoform X1 OS=Danio rerio OX=7955 GN=zfyve21 PE=4 SV=1 CANONICAL=B8A6I2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Spatio-temporal regulation of Wnt and retinoic acid signaling by tbx16/spadetail during zebrafish mesoderm differentiation.", "journal": "BMC Genomics", "date": "2010", "authors": "Mueller Rachel Lockridge, Huang Cheng, Ho Robert K", "evidence": [ { "database": "UniProtKB", "id": "B8A6I1", "url": "https://www.uniprot.org/uniprotkb/B8A6I1" } ], "reference": [ { "type": "PubMed", "id": "20828405", "url": "https://glygen.org/publication/PubMed/20828405" } ] }, { "title": "Transcriptome analysis reveals positive selection on the divergent between topmouth culter and zebrafish.", "journal": "Gene", "date": "2014", "authors": "Ren Li, Tan Xing-Jun, Xiong Ya-Feng, Xu Kang, Zhou Yi, Zhong Huan, Liu Yun, Hong Yun-Han, Liu Shao-Jun", "evidence": [ { "database": "UniProtKB", "id": "B8A6I1", "url": "https://www.uniprot.org/uniprotkb/B8A6I1" } ], "reference": [ { "type": "PubMed", "id": "25267534", "url": "https://glygen.org/publication/PubMed/25267534" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8A6I1", "url": "https://www.uniprot.org/uniprotkb/B8A6I1" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8A6I1", "url": "https://www.uniprot.org/uniprotkb/B8A6I1" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "B8A6I1", "url": "https://www.uniprot.org/uniprotkb/B8A6I1" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] } ], "pathway": [ { "id": "dre:100004144", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004144", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287BE50-1", "protein_name": "Zinc finger FYVE-type containing 21", "gene_name": "ZFYVE21", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSEVAARRDAKKLVRSPSGLRMVPEHRAFGSPFGLEEPQWVPDKECPRCMQCGAKFDFLTRKHHCRRCGKCFCDKCCSQKVALRRMCFVDPVRQCAECALVSHREAEFFDKQLKVLLSGATFLVTFGHSEKPETMVCRLSNNQRFLLLDGSSRHEVEIARISAVQMLSEGFPPGGGNARATGMSLQYPAPGAEGVTQLKLTAGEDANGSRRQATAWLAAMHKAAKLLYESRDQ", "length": 234 }, "evidence": [ { "id": "B8A6I2", "url": "https://omabrowser.org/oma/group/B8A6I2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0YUS1-1", "protein_name": "Zinc finger FYVE-type containing 21", "gene_name": "ZFYVE21", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MSGCEARDAKKLVRSLSGLRMVPEHRSARSPFGLDEPPWVPDKECPRCMQCDTKFDFITRKHHCRRCGKCFCDKCCSKKVPLPRMCFVDPVRQCAECALISQKETEFYDKQLKVLMNGATFFVTLGTSDKSELMVCRLSNNQRYLVLDGNSHYEIEIVQISTVQILTEGFTPGEKDIHTYTSLLESQHITEGGNTRAIGMILHYKVPGSEELTQMKFTASEDFSSNKKLSASWLAAMHKATKLLYESRDQ", "length": 250 }, "evidence": [ { "id": "B8A6I2", "url": "https://omabrowser.org/oma/group/B8A6I2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZVP7-1", "protein_name": "Zinc finger FYVE domain-containing protein 21", "gene_name": "Zfyve21", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": 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"field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 5 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8A6I4-1", "uniprot_ac": "B8A6I4", "uniprot_id": "B8A6I4_DANRE", "mass": { "chemical_mass": 84535.0, "monoisotopic_mass": 84535.0 }, "refseq": { "ac": "NP_001315118", "name": "FHF complex subunit HOOK interacting protein 2A isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315118" }, "gene_names": [ { "name": "fhip2a", "type": "recommended", "evidence": [ { "id": "B8A6I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A6I4" } ] }, { "name": "fam160b1", "type": "synonym", "evidence": [ { "id": "NP_001315118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315118" }, { "id": "B8A6I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A6I4" } ] }, { "name": "fhip2a", "type": "synonym", "evidence": [ { "id": "NP_001315118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315118" } ] }, { "name": "zgc:162264", "type": "synonym", "evidence": [ { "id": "NP_001315118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315118" }, { "id": "B8A6I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A6I4" } ] } ], "protein_names": [ { "name": "FHF complex subunit HOOK interacting protein 2A isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001315118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315118" }, { "id": "B8A6I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A6I4/entry#names_and_taxonomy" } ] }, { "name": "FHF complex subunit HOOK interacting protein 2A isoform X1", "type": "synonym", "evidence": [ { "id": "B8A6I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A6I4/entry#names_and_taxonomy" } ] }, { "name": "family with sequence similarity 160 member B1", "type": "synonym", "evidence": [ { "id": "NP_001315118", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315118" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588730.22572594.1, SRR26395062.1552699.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On or before Jul 28, 2025 this sequence version replaced XP_073775241.1, XP_005157098.1. Sequence Note:.", "evidence": [ { "database": "RefSeq", "id": "NP_001315118", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315118" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8A6I4", "url": "https://www.uniprot.org/uniprotkb/B8A6I4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fhip2a", "url": "https://www.uniprot.org/uniprotkb/B8A6I4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070424-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-63", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000060168", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000060168", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100038786", "url": "https://www.ncbi.nlm.nih.gov/gene/100038786", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019384", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019384", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045668", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045668", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045669", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045669", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100038786", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100038786", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQTEFFF", "url": "https://omabrowser.org/oma/group/VQTEFFF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8A6I3", "url": "https://www.orthodb.org/?gene=B8A6I3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "B8A6I4", "url": "https://www.orthodb.org/?gene=B8A6I4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21705", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21705", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21705:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21705:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10257", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10257", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19311", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19311", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF19314", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19314", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001315118", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001315118", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8A6I3", "url": "https://www.uniprot.org/uniprotkb/B8A6I3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A6I3-1", "url": "https://www.uniprot.org/uniprotkb/B8A6I3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A6I4", "url": "https://www.uniprot.org/uniprotkb/B8A6I4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8A6I4-1", "url": "https://www.uniprot.org/uniprotkb/B8A6I4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070424-63", "url": "https://zfin.org/ZDB-GENE-070424-63", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILTQEERERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLSFYTKLLGRIRQPLLPHINVHRPVQKLVRLCGEVLAAPTENEEIQFLCTVCAKLKQDPYLVNFFLENKNKRLEAGKEAGTDQVKDDPSSPDTGQNQNQNSSLEDSASQAPSPAEAKPSSVHNTLPNNDNYNLVSSLLNLTKSPDGRIVVKACEGLMLIVSLPEPAAAKCLTENTELSQLLTDRLGQFYRALPQSMDPLDIETVESVNWGLDVYNLKEDAAAFAGKRALISFLSWLDYCDQLIKEAHKSAAAVLARAVRERFFVAVMEPQLMQTSEVGILTSTALLNRIIRQVTSEALLQETIYFLLGEETGPETLAGITQHPLRHRLIEHCDHLSDEISIMTLRLFEHLLQKPCQHILQNLVLRCLEERNYSENKQQEEREEREHMENGQPHDAVDLEEDPLFSDLSPDNRLSSPDWLSCSPPASTEHTKPDGKTEVHKIVNSFLCLVPDEAKSSYQVEGTGYDTYLRDAHRQFRDYCGICQKWDWRSTPKPFEKCNLDSPFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSKLSLLPHAHLHEYLLDPYINLAPGCRSLFSVIVRVVGDLMLRTHRIPEFTPKLLLVRKRLLGLEPEGMSVDHVTLLEGVIVLEEFCKELAAIAFVKFHASASTSP", "length": 747, "header": "tr|B8A6I4-1|B8A6I4_DANRE Isoform 1 of FHF complex subunit HOOK interacting protein 2A isoform X1 OS=Danio rerio OX=7955 GN=fhip2a PE=1 SV=1 CANONICAL=B8A6I4-1" }, "isoforms": [ { "isoform_ac": "B8A6I3-1", "url": "https://www.uniprot.org/uniprotkb/B8A6I4/entry#B8A6I3-1", "sequence": { "sequence": "MFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILTQEERERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLSFYTKLLGRIRQPLLPHINVHRPVQKLVRLCGEVLAAPTENEEIQFLCTVCAKLKQDPYLVNFFLENKNKRLEAGKEAGTDQVKDDPSSPDTGQNQNQNSSLEDSASQAPSPAEAKPSSVHNTLPNNDNYNLVSSLLNLTKSPDGRIVVKACEGLMLIVSLPEPAAAKCLTENTELSQLLTDRLGQFYRALPQSMDPLDIETVESVNWGLDVYNLKEDAAAFAGKRALISFLSWLDYCDQLIKEAHKSAAAVLARAVRERFFVAVMEPQLMQTSEVGILTSTALLNRIIRQVTSEALLQETIYFLLGEETGPETLAGITQHPLRHRLIEHCDHLSDEISIMTLRLFEHLLQKPCQHILQNLVLRCLEERNYSENKQQEEREEREHMENGQPHDAV", "length": 503, "header": "tr|B8A6I3-1|B8A6I4_DANRE Computationally mapped isoform of FHF complex subunit HOOK interacting protein 2A isoform X1 OS=Danio rerio OX=7955 GN=fhip2a PE=1 SV=1 CANONICAL=B8A6I4-1" }, "locus": {} }, { "isoform_ac": "B8A6I4-1", "url": "https://www.uniprot.org/uniprotkb/B8A6I4/entry#B8A6I4-1", "sequence": { "sequence": "MFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILTQEERERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLSFYTKLLGRIRQPLLPHINVHRPVQKLVRLCGEVLAAPTENEEIQFLCTVCAKLKQDPYLVNFFLENKNKRLEAGKEAGTDQVKDDPSSPDTGQNQNQNSSLEDSASQAPSPAEAKPSSVHNTLPNNDNYNLVSSLLNLTKSPDGRIVVKACEGLMLIVSLPEPAAAKCLTENTELSQLLTDRLGQFYRALPQSMDPLDIETVESVNWGLDVYNLKEDAAAFAGKRALISFLSWLDYCDQLIKEAHKSAAAVLARAVRERFFVAVMEPQLMQTSEVGILTSTALLNRIIRQVTSEALLQETIYFLLGEETGPETLAGITQHPLRHRLIEHCDHLSDEISIMTLRLFEHLLQKPCQHILQNLVLRCLEERNYSENKQQEEREEREHMENGQPHDAVDLEEDPLFSDLSPDNRLSSPDWLSCSPPASTEHTKPDGKTEVHKIVNSFLCLVPDEAKSSYQVEGTGYDTYLRDAHRQFRDYCGICQKWDWRSTPKPFEKCNLDSPFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSKLSLLPHAHLHEYLLDPYINLAPGCRSLFSVIVRVVGDLMLRTHRIPEFTPKLLLVRKRLLGLEPEGMSVDHVTLLEGVIVLEEFCKELAAIAFVKFHASASTSP", "length": 747, "header": "tr|B8A6I4-1|B8A6I4_DANRE Isoform 1 of FHF complex subunit HOOK interacting protein 2A isoform X1 OS=Danio rerio OX=7955 GN=fhip2a PE=1 SV=1 CANONICAL=B8A6I4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8A6I3", "url": "https://www.uniprot.org/uniprotkb/B8A6I3" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:100038786", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100038786", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A3I5-1", "protein_name": "FHF complex subunit HOOK interacting protein 2A", "gene_name": "Fhip2a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MERSGQPQQGRRRRIEELSRSSREKLLQSRDRMFSKLTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLVFYTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLENKSKSLMSRGALSVISEDDPKGQDPVSGDVSQCHQPQELSGATGVAHAESEEEPPHQMDDLNASLDDLSVTSLPEASAIRPNQDYNLVNSLLNLTRSPDGRIAVKACEGLMLLVSLPEPAAAKCLAQSTCLCELLTGRLTSLYKALPQSVDPLDIETVEAVNWGLDSYSHKEDTSAFPGKRALISFLSWFDYCDQLIKEAQKTAAVALAKAIHERFFVGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDVLLQEMVVFILGEQREPETLSEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRNLEERNYTEYKPLCPEDKDVVENGLIAGAVDLEEDPLFTDISPDNTLPNQEWICSPRASPDHPKNDGKTEVHKVVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCAVCLRWEWPGAPKPLEKCDLEAAFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHTHEYLLDPYVNLASGCRSLFSVIVRVVGDLMVRIQRIQDFTPKLLLVRKRLLGLEPEGPIVDHITLLEGVIVLEEFCKELAAIAFVKFHASSTP", "length": 796 }, "evidence": [ { "id": "MGI:2147545", "url": "https://alliancegenome.org/gene/MGI:2147545#orthology", "database": "AGR" }, { "id": "HGNC:29320", "url": "https://alliancegenome.org/gene/HGNC:29320#orthology", "database": "AGR" }, { "id": "B8A6I4", "url": "https://omabrowser.org/oma/group/B8A6I4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1S4V3-1", "protein_name": "FHF complex subunit HOOK interacting protein 2A", "gene_name": "FHIP2A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLVILVQEESEREFGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLVFYTKLLGKIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLENKLKSLASKEAANATSEDIPKGQDSLSADTGQCFRPEELSGASGAESTESEEEPPQQIDDLSAGLDGLSVAALPEATVVRPNQDYNLVNSLLNLTRSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLASLYRALPQSVDPLDIETVEAINWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKTAAVALAKAVRERFFIGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDILLQEMVFFILGEQREPETLAEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRNLEERNYTEYKPVCPEDKDVMENGLIAGAVDLEEDPLFTDISPDNTLSNQEWLSSSPPTTPDHPKNDGKTEVHKIVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCAICLRWEWPGSPKALEKCNLEAAFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHIHEYLLDPYVNLASGCRSLFSVIVRVVGDLMVRIQRIQDFTPKLLLVRKRLLGLEPEGPVIDHITLLEGVIVLEEFCKELAAIAFVKYHAASTP", "length": 765 }, "evidence": [ { "id": "B8A6I4", "url": "https://omabrowser.org/oma/group/B8A6I4/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3X6C8-1", "protein_name": "FHF complex subunit HOOK interacting protein 2A", "gene_name": "FHIP2A", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MERPRQPQQGRRRRIEELSRSSREKLLQSRDKMFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLVILVQEENEREFGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLVFYTKLLGKIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLENKFKSLVSQGGPNAISEDVLKSQDSLSTDTGQSCQAEEPLGASGTEDQPSHQMGDLSTSLENLSVTALPEATVVRPNQDYNLVNSLLNLTRSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLASLYKALPQSVDPLDIETVEAVNWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKTAAVALAKAVHERFFIGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDILLQEMVFFILGEQREPETLAEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRNLEERNYTEYKPVCPEDKDVVENGLIAGAVDLEEDPLFTDISPDNTLSNQEWLSSSPPATPDHPKTDGKTEVHKIVNSFLCLVPDEAKSSYHVEGTGYDTYLRDAHRQFRDYCAICLRWEWPGSPKALERCNLEAAFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHIHEYLLDPYVNLASGCRSLFSVIVRVVGDLMVRIQRIQDFTPKLLLVRKRLLGLEPEGPVIDHITLLEGVIVLEEFCKELAAIAFVKYHAASTP", "length": 792 }, "evidence": [ { "id": "B8A6I4", "url": "https://omabrowser.org/oma/group/B8A6I4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5W0V3-1", "protein_name": "FHF complex subunit HOOK interacting protein 2A", "gene_name": "FHIP2A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFSKFTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLVFYTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLENKMKSLASKGVPNVISEDTLKGQDSLSTDTGQSRQPEELSGATGMEQTELEDEPPHQMDHLSTSLDNLSVTSLPEASVVCPNQDYNLVNSLLNLTRSPDGRIAVKACEGLMLLVSLPEPAAAKCLTQSTCLCELLTDRLASLYKALPQSVDPLDIETVEAINWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKTAAVALAKAVHERFFIGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDVLLQEMVFFILGEQREPETLAEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRNLEERNYTEYKPLCPEDKDVVENGLIAGAVDLEEDPLFTDISPENTLPNQEWLSSSPPATPDHPKNDGKTEVHKIVNSFLCLVPDDAKSSYHVEGTGYDTYLRDAHRQFRDYCAICLRWEWPGSPKALEKCNLEAAFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHIHEYLLDPYVNLAPGCRSLFSVIVRVVGDLMLRIQRIQDFTPKLLLVRKRLLGLEPEGPIIDHITLLEGVIVLEEFCKELAAIAFVKYHASSTP", "length": 765 }, "evidence": [ { "id": "MGI:2147545", "url": "https://alliancegenome.org/gene/MGI:2147545#orthology", "database": "AGR" }, { "id": "HGNC:29320", "url": "https://alliancegenome.org/gene/HGNC:29320#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-63#orthology", "database": "AGR" }, { "id": "B8A6I4", "url": "https://omabrowser.org/oma/group/B8A6I4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CDM8-1", "protein_name": "FHF complex subunit HOOK interacting protein 2A", "gene_name": "Fhip2a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFSKLTSILQHAVEALAPSLPLQEDFVYHWKAITHYYIETSDDKAPVTDTNIPSHLEQMLDILVQEENERESGETGPCMEYLLHHKILETLYTLGKADCPPGMKQQVLVFYTKLLGRIRQPLLPHINVHRPVQKLIRLCGEVLATPTENEEIQFLCIVCAKLKQDPYLVNFFLENKSKSLVSRGALSVISEDGPKGQDPGSGDVSQCQQPQELSGATGVEPTESEEEPPHQMDDLSASLDDLNVTSLPEASAVRPNQDYNLVNSLLNLTRSPDGRIAVKACEGLMLLVSLPEPAAAKCLAQSTCLCELLTGRLTSLYKALPQSVDPLDIETVEAVNWGLDSYSHKEDASAFPGKRALISFLSWFDYCDQLIKEAQKTAAVALAKAIHERFFVGVMEPQLMQTSEMGILTSTALLHRIVRQVTSDVLLQEMVVFILGEQREPETLSEISRHPLRHRLIEHCDHISDEISIMTLRMFEHLLQKPNEHILYNLVLRNLEERNYTENKPSCPEDKDVVENGLIAGAVDLEEDPLFTDISPDNTLPNQEWICSPRTSPDHPKNDGKTEVHKVVNSFLCLVPDDAKSSYHVEGTGYDTYLRDAHRQFRDYCAICSRWEWPGAPKPLEKCDLEAAFFEGHFLKVLFDRMGRILDQPYDVNLQVTSVLSRLSLFPHPHTHEYLLDPYINLASGCRSLFSVIVRVVGDLMVRIQRIQDFTPKLLLVRKRLLGLEPEGPIVDHITLLEGVIVLEEFCKELAAIAFVKYHASATP", "length": 764 }, "evidence": [ { "id": "MGI:2147545", "url": "https://alliancegenome.org/gene/MGI:2147545#orthology", "database": "AGR" }, { "id": "HGNC:29320", "url": "https://alliancegenome.org/gene/HGNC:29320#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070424-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070424-63#orthology", "database": "AGR" }, { "id": "B8A6I4", "url": "https://omabrowser.org/oma/group/B8A6I4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 207, "end_pos": 209, "annotation": "n_glycosylation_sequon" }, { "start_pos": 246, "end_pos": 248, "annotation": "n_glycosylation_sequon" }, { "start_pos": 478, "end_pos": 480, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8A6I4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8A6I4" }, { "id": "PF19314", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF19314" } ], 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"mass": { "chemical_mass": 24486.0, "monoisotopic_mass": 24486.0 }, "refseq": { "ac": "NP_001139028", "name": "enamelin precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139028" }, "gene_names": [ { "name": "enam", "type": "recommended", "evidence": [ { "id": "B8JHY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ] }, { "name": "enam", "type": "synonym", "evidence": [ { "id": "NP_001139028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139028" } ] }, { "name": "fa93e10", "type": "synonym", "evidence": [ { "id": "NP_001139028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139028" }, { "id": "B8JHY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ] }, { "name": "si:dkey-22i16.3", "type": "synonym", "evidence": [ { "id": "NP_001139028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139028" }, { "id": "B8JHY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ] }, { "name": "wu:fa93e10", "type": "synonym", "evidence": [ { "id": "NP_001139028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139028" }, { "id": "B8JHY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ] } ], "protein_names": [ { "name": "Enamelin precursor", "type": "synonym", "evidence": [ { "id": "B8JHY7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JHY7/entry#names_and_taxonomy" } ] }, { "name": "enamelin precursor", "type": "synonym", "evidence": [ { "id": "NP_001139028", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139028" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01021614.1, GDQQ01035783.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000001.1. On Mar 5, 2009 this sequence version replaced XP_703105.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001139028", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139028" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JHY7", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "enam", "url": "https://www.uniprot.org/uniprotkb/B8JHY7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-071005-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-071005-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092730", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092730", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "555617", "url": "https://www.ncbi.nlm.nih.gov/gene/555617", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:555617", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555617", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MELFRVY", "url": "https://omabrowser.org/oma/group/MELFRVY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JHY7", "url": "https://www.orthodb.org/?gene=B8JHY7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001139028", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139028", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JHY7", "url": "https://www.uniprot.org/uniprotkb/B8JHY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JHY7-1", "url": "https://www.uniprot.org/uniprotkb/B8JHY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-071005-4", "url": "https://zfin.org/ZDB-GENE-071005-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKAVALLMCLLGSSLAAPAPDSGSNEQAIASHANTALQLMELYRMLGQLRQQGYGAVAGPQLPAAPAAPVDPAPVDTQPQVSPQVPQQGFFFNPAAFAPTGDGSDEEVAPQYRGFYPHYGYHQPAQPAAPLNSDEAEGAEAEGAEAEAGAEAGAEAGAEAGAEVGAEAEPAGTAATVDAAAANEILPVDVAEPAADVIAAAVAAVDPALSPEAPAVAMEIDTTVVGPDVAAGEQVLMAEAPDAALSV", "length": 247, "header": "tr|B8JHY7-1|B8JHY7_DANRE Isoform 1 of Enamelin precursor OS=Danio rerio OX=7955 GN=enam PE=4 SV=1 CANONICAL=B8JHY7-1" }, "isoforms": [ { "isoform_ac": "B8JHY7-1", "url": "https://www.uniprot.org/uniprotkb/B8JHY7/entry#B8JHY7-1", "sequence": { "sequence": "MKAVALLMCLLGSSLAAPAPDSGSNEQAIASHANTALQLMELYRMLGQLRQQGYGAVAGPQLPAAPAAPVDPAPVDTQPQVSPQVPQQGFFFNPAAFAPTGDGSDEEVAPQYRGFYPHYGYHQPAQPAAPLNSDEAEGAEAEGAEAEAGAEAGAEAGAEAGAEVGAEAEPAGTAATVDAAAANEILPVDVAEPAADVIAAAVAAVDPALSPEAPAVAMEIDTTVVGPDVAAGEQVLMAEAPDAALSV", "length": 247, "header": "tr|B8JHY7-1|B8JHY7_DANRE Isoform 1 of Enamelin precursor OS=Danio rerio OX=7955 GN=enam PE=4 SV=1 CANONICAL=B8JHY7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Saltatory control of isometric growth in the zebrafish caudal fin is disrupted in long fin and rapunzel mutants.", "journal": "Dev. Biol.", "date": "2003", "authors": "Goldsmith Matthew I, Fisher Shannon, Waterman Rick, Johnson Stephen L", "evidence": [ { "database": "UniProtKB", "id": "B8JHY7", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ], "reference": [ { "type": "PubMed", "id": "12871703", "url": "https://glygen.org/publication/PubMed/12871703" } ] }, { "title": "A developmental transition in growth control during zebrafish caudal fin development.", "journal": "Dev. Biol.", "date": "2006", "authors": "Goldsmith Matthew I, Iovine M Kathryn, O'Reilly-Pol Thomas, Johnson Stephen L", "evidence": [ { "database": "UniProtKB", "id": "B8JHY7", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ], "reference": [ { "type": "PubMed", "id": "16844108", "url": "https://glygen.org/publication/PubMed/16844108" } ] }, { "title": "Bone growth in zebrafish fins occurs via multiple pulses of cell proliferation.", "journal": "Dev. 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Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JHY7", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Live Monitoring of Blastemal Cell Contributions during Appendage Regeneration.", "journal": "Curr. Biol.", "date": "2016", "authors": "Tornini Valerie A, Puliafito Alberto, Slota Leslie A, Thompson John D, Nachtrab Gregory, Kaushik Anna-Lila, Kapsimali Marika, Primo Luca, Di Talia Stefano, Poss Kenneth D", "evidence": [ { "database": "UniProtKB", "id": "B8JHY7", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ], "reference": [ { "type": "PubMed", "id": "27839971", "url": "https://glygen.org/publication/PubMed/27839971" } ] }, { "title": "The seahorse genome and the evolution of its specialized morphology.", "journal": "Nature", "date": "2016", "authors": "Lin Qiang, Fan Shaohua, Zhang Yanhong, Xu Meng, Zhang Huixian, Yang Yulan, Lee Alison P, Woltering Joost M, Ravi Vydianathan, Gunter Helen M, Luo Wei, Gao Zexia, Lim Zhi Wei, Qin Geng, Schneider Ralf F, Wang Xin, Xiong Peiwen, Li Gang, Wang Kai, Min Jiumeng, Zhang Chi, Qiu Ying, Bai Jie, He Weiming, Bian Chao, Zhang Xinhui, Shan Dai, Qu Hongyue, Sun Ying, Gao Qiang, Huang Liangmin, Shi Qiong, Meyer Axel, Venkatesh Byrappa", "evidence": [ { "database": "UniProtKB", "id": "B8JHY7", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ], "reference": [ { "type": "PubMed", "id": "27974754", "url": "https://glygen.org/publication/PubMed/27974754" } ] }, { "title": "Regrowth of zebrafish caudal fin regeneration is determined by the amputated length.", "journal": "Sci. Rep.", "date": "2020", "authors": "Uemoto Toshiaki, Abe Gembu, Tamura Koji", "evidence": [ { "database": "UniProtKB", "id": "B8JHY7", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ], "reference": [ { "type": "PubMed", "id": "31959817", "url": "https://glygen.org/publication/PubMed/31959817" } ] }, { "title": "Coevolution of enamel, ganoin, enameloid, and their matrix SCPP genes in osteichthyans.", "journal": "IScience", "date": "2021", "authors": "Kawasaki Kazuhiko, Keating Joseph N, Nakatomi Mitsushiro, Welten Monique, Mikami Masato, Sasagawa Ichiro, Puttick Mark N, Donoghue Philip C J, Ishiyama Mikio", "evidence": [ { "database": "UniProtKB", "id": "B8JHY7", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ], "reference": [ { "type": "PubMed", "id": "33506188", "url": "https://glygen.org/publication/PubMed/33506188" } ] }, { "title": "Clinical, genetic, epidemiologic, evolutionary, and functional delineation of TSPEAR-related autosomal recessive ectodermal dysplasia 14.", "journal": "HGG Adv.", "date": "2023", "authors": "Jackson Adam, Lin Sheng-Jia, Jones Elizabeth A, Chandler Kate E, Orr David, Moss Celia, Haider Zahra, Ryan Gavin, Holden Simon, Harrison Mike, Burrows Nigel, Jones Wendy D, Loveless Mary, Petree Cassidy, Stewart Helen, Low Karen, Donnelly Deirdre, Lovell Simon, Drosou Konstantina, , , Varshney Gaurav K, Banka Siddharth", "evidence": [ { "database": "UniProtKB", "id": "B8JHY7", "url": "https://www.uniprot.org/uniprotkb/B8JHY7" } ], "reference": [ { "type": "PubMed", "id": "37009414", "url": "https://glygen.org/publication/PubMed/37009414" } ] } ], "pathway": [ { "id": "dre:555617", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555617", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 10 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JI67-1", "uniprot_ac": "B8JI67", "uniprot_id": "TMM81_DANRE", "mass": { "chemical_mass": 29307.0, "monoisotopic_mass": 29307.0 }, "refseq": { "ac": "NP_001429596", "name": "transmembrane protein 81 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429596" }, "gene_names": [ { "name": "tmem81", "type": "recommended", "evidence": [ { "id": "B8JI67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JI67" } ] }, { "name": "si:dkey-48j7.3", "type": "synonym", "evidence": [ { "id": "NP_001429596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429596" }, { "id": "B8JI67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JI67" } ] }, { "name": "tmem81", "type": "synonym", "evidence": [ { "id": "NP_001429596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429596" } ] } ], "protein_names": [ { "name": "Transmembrane protein 81", "type": "recommended", "evidence": [ { "id": "B8JI67", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JI67/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 81 precursor", "type": "synonym", "evidence": [ { "id": "NP_001429596", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429596" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588722.10609655.1, EH489490.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN18715719, SAMN18715720 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000008.1. On Aug 20, 2025 this sequence version replaced XP_009302307.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001429596", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429596" } ] }, { "annotation": "Essential fertilization factor required for male fertility. Part of a conserved trimeric sperm complex with the essential fertilization factors IZUMO1 and SPACA6 which bridges sperm and oocyte membranes during fertilization by binding to IZUMO1R/JUNO on the oocyte.", "evidence": [ { "database": "UniProtKB", "id": "B8JI67", "url": "https://www.uniprot.org/uniprotkb/B8JI67#function" }, { "database": "PubMed", "id": "39423812", "url": "https://glygen.org/publication/PubMed/39423812" }, { "database": "UniProtKB", "id": "A0AC58G9V9", "url": "https://www.uniprot.org/uniprotkb/A0AC58G9V9#function" }, { "database": "UniProtKB", "id": "ARBA00049937", "url": "https://www.uniprot.org/uniprotkb/ARBA00049937#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JI67", "url": "https://www.uniprot.org/uniprotkb/B8JI67" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmem81", "url": "https://www.uniprot.org/uniprotkb/B8JI67", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-418", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-418", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "B8JI67", "url": "https://alphafold.ebi.ac.uk/entry/B8JI67", "database": "AlphaFoldDB", "categories": [] }, { "id": "ENSDARG00000042536", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000042536", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100006525", "url": "https://www.ncbi.nlm.nih.gov/gene/100006525", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039293", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039293", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "ECLTNWL", "url": "https://omabrowser.org/oma/group/ECLTNWL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JI67", "url": "https://www.orthodb.org/?gene=B8JI67", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR35670", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35670", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR35670:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR35670:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PR:B8JI67", "url": "https://proconsortium.org/cgi-bin/entry_pro?id=PR:B8JI67", "database": "PRO", "categories": [ "Protein" ] }, { "id": "NP_001429596", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429596", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58G9V9", "url": "https://www.uniprot.org/uniprotkb/A0AC58G9V9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G9V9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G9V9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JI67", "url": "https://www.uniprot.org/uniprotkb/B8JI67", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JI67-1", "url": "https://www.uniprot.org/uniprotkb/B8JI67-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-418", "url": "https://zfin.org/ZDB-GENE-081104-418", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MALSTLWLVLMLWTSLFSDSQCSTLSQAELQELEQIHTWVVSRSFPCSVTCGLGLLTQELCPIGVTRNISTSSCKLRTISCLDSWQCGLKTQTATVGRRLVLDCLEEVMEAMGRFSFVVSWRFAFAIITTDDSLFTRYEALSLDKVVLDPLREEDSGTYRCDVLDTGKRRVKRMYKGVKVLSPKDLSLDFAQGLIHWEIPESRFANLTSSRKVYSSSTIRNIVIISVPLSFAIAVVIFIFLFCYSRRARRAAHLCQDNI", "length": 259, "header": "sp|B8JI67-1|TMM81_DANRE Isoform 1 of Transmembrane protein 81 OS=Danio rerio OX=7955 GN=tmem81 PE=1 SV=1 CANONICAL=B8JI67-1" }, "isoforms": [ { "isoform_ac": "A0AC58G9V9-1", "url": "https://www.uniprot.org/uniprotkb/B8JI67/entry#A0AC58G9V9-1", "sequence": { "sequence": "MALSTLWLVLMLWTSLFSDSQCSTLSQAELQELEQIHTWVVSRSFPCSVTCGLGLLTQELCPIGVTRNISTSSCKLRTISCLDSWQCGLKTQTATVGRRLVLDCLEEVMEAMGRFSFVVSWRFAFAIITTDDSLFTRYEALSLDKVVLDPLREEDSGTYRCDVLDTGKRRVKRMYKGVKVLSPKDLSLDFAQGLIHWEIPESRFANLTSSRKVYSSSTIRNIVIISVPLSFAIAVVIFIFLFCYSRRARRAAHLCQDNI", "length": 259, "header": "tr|A0AC58G9V9-1|A0AC58G9V9_DANRE Computationally mapped isoform of Transmembrane protein 81 OS=Danio rerio OX=7955 GN=tmem81 PE=4 SV=1 CANONICAL=B8JI67-1" }, "locus": {} }, { "isoform_ac": "B8JI67-1", "url": "https://www.uniprot.org/uniprotkb/B8JI67/entry#B8JI67-1", "sequence": { "sequence": "MALSTLWLVLMLWTSLFSDSQCSTLSQAELQELEQIHTWVVSRSFPCSVTCGLGLLTQELCPIGVTRNISTSSCKLRTISCLDSWQCGLKTQTATVGRRLVLDCLEEVMEAMGRFSFVVSWRFAFAIITTDDSLFTRYEALSLDKVVLDPLREEDSGTYRCDVLDTGKRRVKRMYKGVKVLSPKDLSLDFAQGLIHWEIPESRFANLTSSRKVYSSSTIRNIVIISVPLSFAIAVVIFIFLFCYSRRARRAAHLCQDNI", "length": 259, "header": "sp|B8JI67-1|TMM81_DANRE Isoform 1 of Transmembrane protein 81 OS=Danio rerio OX=7955 GN=tmem81 PE=1 SV=1 CANONICAL=B8JI67-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "The zebrafish reference genome sequence and its relationship to the human genome.", "journal": "Nature", "date": "2013", "authors": "Howe Kerstin, Clark Matthew D, Torroja Carlos F, Torrance James, Berthelot Camille, Muffato Matthieu, Collins John E, Humphray Sean, McLaren Karen, Matthews Lucy, McLaren Stuart, Sealy Ian, Caccamo Mario, Churcher Carol, Scott Carol, Barrett Jeffrey C, Koch Romke, Rauch Gerd-J\u00f6rg, White Simon, Chow William, Kilian Britt, Quintais Leonor T, Guerra-Assun\u00e7\u00e3o Jos\u00e9 A, Zhou Yi, Gu Yong, Yen Jennifer, Vogel Jan-Hinnerk, Eyre Tina, Redmond Seth, Banerjee Ruby, Chi Jianxiang, Fu Beiyuan, Langley Elizabeth, Maguire Sean F, Laird Gavin K, Lloyd David, Kenyon Emma, Donaldson Sarah, Sehra Harminder, Almeida-King Jeff, Loveland Jane, Trevanion Stephen, Jones Matt, Quail Mike, Willey Dave, Hunt Adrienne, Burton John, Sims Sarah, McLay Kirsten, Plumb Bob, Davis Joy, Clee Chris, Oliver Karen, Clark Richard, Riddle Clare, Elliot David, Eliott David, Threadgold Glen, Harden Glenn, Ware Darren, Begum Sharmin, Mortimore Beverley, Mortimer Beverly, Kerry Giselle, Heath Paul, Phillimore Benjamin, Tracey Alan, Corby Nicole, Dunn Matthew, Johnson Christopher, Wood Jonathan, Clark Susan, Pelan Sarah, Griffiths Guy, Smith Michelle, Glithero Rebecca, Howden Philip, Barker Nicholas, Lloyd Christine, Stevens Christopher, Harley Joanna, Holt Karen, Panagiotidis Georgios, Lovell Jamieson, Beasley Helen, Henderson Carl, Gordon Daria, Auger Katherine, Wright Deborah, Collins Joanna, Raisen Claire, Dyer Lauren, Leung Kenric, Robertson Lauren, Ambridge Kirsty, Leongamornlert Daniel, McGuire Sarah, Gilderthorp Ruth, Griffiths Coline, Manthravadi Deepa, Nichol Sarah, Barker Gary, Whitehead Siobhan, Kay Michael, Brown Jacqueline, Murnane Clare, Gray Emma, Humphries Matthew, Sycamore Neil, Barker Darren, Saunders David, Wallis Justene, Babbage Anne, Hammond Sian, Mashreghi-Mohammadi Maryam, Barr Lucy, Martin Sancha, Wray Paul, Ellington Andrew, Matthews Nicholas, Ellwood Matthew, Woodmansey Rebecca, Clark Graham, Cooper James D, Cooper James, Tromans Anthony, Grafham Darren, Skuce Carl, Pandian Richard, Andrews Robert, Harrison Elliot, Kimberley Andrew, Garnett Jane, Fosker Nigel, Hall Rebekah, Garner Patrick, Kelly Daniel, Bird Christine, Palmer Sophie, Gehring Ines, Berger Andrea, Dooley Christopher M, Ersan-\u00dcr\u00fcn Z\u00fcbeyde, Eser Cigdem, Geiger Horst, Geisler Maria, Karotki Lena, Kirn Anette, Konantz Judith, Konantz Martina, Oberl\u00e4nder Martina, Rudolph-Geiger Silke, Teucke Mathias, Lanz Christa, Raddatz G\u00fcnter, Osoegawa Kazutoyo, Zhu Baoli, Rapp Amanda, Widaa Sara, Langford Cordelia, Yang Fengtang, Schuster Stephan C, Carter Nigel P, Harrow Jennifer, Ning Zemin, Herrero Javier, Searle Steve M J, Enright Anton, Geisler Robert, Plasterk Ronald H A, Lee Charles, Westerfield Monte, de Jong Pieter J, Zon Leonard I, Postlethwait John H, N\u00fcsslein-Volhard Christiane, Hubbard Tim J P, Roest Crollius Hugues, Rogers Jane, Stemple Derek L", "evidence": [ { "database": "UniProtKB", "id": "B8JI67", "url": "https://www.uniprot.org/uniprotkb/B8JI67" } ], "reference": [ { "type": "PubMed", "id": "23594743", "url": "https://glygen.org/publication/PubMed/23594743" } ] }, { "title": "A conserved fertilization complex bridges sperm and egg in vertebrates.", "journal": "Cell", "date": "2024-12-12", "authors": "Deneke Victoria E, Blaha Andreas, Lu Yonggang, Suwita Johannes P, Draper Jonne M, Phan Clara S, Panser Karin, Schleiffer Alexander, Jacob Laurine, Humer Theresa, Stejskal Karel, Krssakova Gabriela, Roitinger Elisabeth, Handler Dominik, Kamoshita Maki, Vance Tyler D R, Wang Xinyin, Surm Joachim M, Moran Yehu, Lee Jeffrey E, Ikawa Masahito, Pauli Andrea", "evidence": [ { "database": "UniProtKB", "id": "B8JI67", "url": "https://www.uniprot.org/uniprotkb/B8JI67" } ], "reference": [ { "type": "PubMed", "id": "39423812", "url": "https://glygen.org/publication/PubMed/39423812" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "Q0VCB1-1", "protein_name": "Transmembrane protein 81", "gene_name": "TMEM81", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKTSATSFIPGSLVLAFCLPVVATSPKTLAIPEKLQEAVGKVTVNATTCTVICGLGFKEETVCEVGPDGVRRKCKSQRLECLTNWLCGMLHFTLLIGKEFKLSCLSPDILEIGQGAFRFTWRLARGIISTDDEVFKPFRASSYFIKFQSIQEYDSGTYRCDVQLLKNLRLVKRLYFGLRVLPPNLVNLNFHQSLTEDQKLVDEGLEVNLDNYSRPQHPPWKKKVAIAVGIGVAGGVTGGVLVSIVLCGRLSVIHSSASLETLQALLPKGGMLRKPD", "length": 276 }, "evidence": [ { "id": "B8JI67", "url": "https://omabrowser.org/oma/group/B8JI67/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6AXW8-1", "protein_name": "Transmembrane protein 81", "gene_name": "Tmem81", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKAVATVFICGSLVLITYLPLVVTSPQTLAIPEKLRQAVGRVVVNATACSVTCGLGYKEETSCEVGPDGVRRDCRSQRLECLTNWICGMLHFTIIQRQQFELNCLSSDILTKGQEAFRFTWKLARGIISTNDELFKPFRANSPFLRFKPAYESDSGTYRCDVQQLKNLKLVKRLYFGLRVLPPKLVNLNFQQSLTEDQKLAEEGWEVHLDNQSQPHLPGWRKKVSLALGVGIAAGVVGGVLVNVALCRVLGGTGGNGNLSSL", "length": 262 }, "evidence": [ { "id": "MGI:1921876", "url": "https://alliancegenome.org/gene/MGI:1921876#orthology", "database": "AGR" }, { "id": "HGNC:32349", "url": "https://alliancegenome.org/gene/HGNC:32349#orthology", "database": "AGR" }, { "id": "B8JI67", "url": "https://omabrowser.org/oma/group/B8JI67/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P7N7-1", "protein_name": "Transmembrane protein 81", "gene_name": "TMEM81", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKVLATSFVLGSLGLAFYLPLVVTTPKTLAIPEKLQEAVGKVIINATTCTVTCGLGYKEETVCEVGPDGVRRKCQTRRLECLTNWICGMLHFTILIGKEFELSCLSSDILEFGQEAFRFTWRLARGVISTDDEVFKPFQANSHFVKFKYAQEYDSGTYRCDVQLVKNLRLVKRLYFGLRVLPPNLVNLNFHQSLTEDQKLIDEGLEVNLDSYSKPHHPKWKKKVASALGIGIAIGVVGGVLVRIVLCALRGGLQQ", "length": 255 }, "evidence": [ { "id": "MGI:1921876", "url": "https://alliancegenome.org/gene/MGI:1921876#orthology", "database": "AGR" }, { "id": "HGNC:32349", "url": "https://alliancegenome.org/gene/HGNC:32349#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-418", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-418#orthology", "database": "AGR" }, { "id": "B8JI67", "url": "https://omabrowser.org/oma/group/B8JI67/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9D5K1-1", "protein_name": "Transmembrane protein 81", "gene_name": "Tmem81", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKTGAIVFILRSLLSITYLPLVLMTLDIPEELQKAVGRVIVNATGCSVTCGLGYKEETECEVGPDGVRRNCTFQRLECVTNWICGMLHFTIVHGKTFELNCLSSDILEKGQEAFRFTWRLARGIISTNDELFRPFRANSPFIGFKPAYEYNAGTYRCDVQLLKNLKFVKRLYFGLRVLPPKLVNLNFQQSLTEDQKLIDKGWEVNLDNGSKPHLPVWQRKVTSALGIGIVAGVVGGVLVSVAVFKALGGTDGSGGRTRL", "length": 259 }, "evidence": [ { "id": "MGI:1921876", "url": "https://alliancegenome.org/gene/MGI:1921876#orthology", "database": "AGR" }, { "id": "HGNC:32349", "url": "https://alliancegenome.org/gene/HGNC:32349#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-418", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-418#orthology", "database": "AGR" }, { "id": "B8JI67", "url": "https://omabrowser.org/oma/group/B8JI67/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "sperm-egg recognition", "id": "GO:0035036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035036", "evidence": [ { "database": "UniProtKB", "id": "B8JI67", "url": "https://www.uniprot.org/uniprotkb/B8JI67" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B8JI67", "url": "https://www.uniprot.org/uniprotkb/B8JI67" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 206, "end_pos": 208, "annotation": "n_glycosylation_sequon" }, { 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"https://www.ebi.ac.uk/interpro/entry/pfam/PF15870", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001314684", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314684", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58JBI7", "url": "https://www.uniprot.org/uniprotkb/A0AC58JBI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58JBI7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58JBI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JII5", "url": "https://www.uniprot.org/uniprotkb/B8JII5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JII5-1", "url": "https://www.uniprot.org/uniprotkb/B8JII5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061013-448", "url": "https://zfin.org/ZDB-GENE-061013-448", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": 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"length": 1251, "header": "tr|B8JII5-1|B8JII5_DANRE Isoform 1 of Uncharacterized protein LOC564848 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=B8JII5-1" }, "isoforms": [ { "isoform_ac": "A0AC58JBI7-1", "url": "https://www.uniprot.org/uniprotkb/B8JII5/entry#A0AC58JBI7-1", "sequence": { "sequence": "MFPSTALFDEIDCPFLQSGRCQRPYCLYNHSKDSSSDVMNTKGLGDPKVTSANGSFHTTEDNYACLEELERINKEIEAVRSEVEKEQKRLSQYQTSQSLTQTGQCSGKYLRTTKSRPKDQNGNHLKSKKPVCSTSGQKYVVDRARPKTDLEYDPCSNFSADLLSSSSAECKLKSSDKVDIDHGLKSKQTGKIVQPLSSHFDDSEDKGTLVIDIPSLTKDHRKHKPKQESAIIKTHVLERNGAVNNDLSNQQTNPNQHKEKSSDGLPSHDMKCTLSDQENARTLVKPMMITEEQESSEGELVIDVSQFEDEHKLPQQRETKNKELLDLPKLCPISNAPAEHYKEANDGQIIKGITMANHPGKDIEPFLEDLREEPVAEPNNFTNINMETFVKQKEEKAHNLENVLDDISTCLNNMRSQSDELKTIQDVKMLPVNSVYGDECISSQFPRSALQNLTSREPQNSSISGYALKSENVSSKDISQIHQQYFPMVSSQSLPSPLHKAEEHRFLGPPHTQSLTETSWVTLQSSHGEPFVHNTPAYVSEIDFGVVSAPSNSQLNPRTVESIEKLPTSNVSYSAACDMTVPSQTFATMAGNNNEPIVVDSSSDAELRYSDLDLSDTDPMEECYRIFMEANQSEAPVVQCDAPDKVGTEMKSNPVALLKKRVAHVAKFEPASKSKAQIIVPLQEGTSHLNVPSRSQLCQRRAAILTAAVKGCQSQVINSAPKKVYTSNVHQIHQSAVQNSCVGIIPVGATLQLGTNLHFIVPEGNCALPLTLIPTTMSVQRPPQPSPPVQLAPAQHPTQPANYTPAKVMGVKRKAKVHHEVGAKVPHDVRQRYVNLFVEEFLKSSVTVQDAFEKALAEEKIVYDRSINKLKYLSIAVNALKRLKNQNILPAKAPSERDQHVSRGNVPLNTQALQGPGDLTLFEQLKEHILSEDLLQVNNFPRKHQDKADFAIQYGDTKKGISDPLKRICCRCGATFSVDRSGKHTRREECNYHYGKVIENRVPGGVETRYSCCENAVGSPGCQVFNLHVHDAVSLQGFVSSLHQSAVGKTCPGIYAIDTQTCYTTQGLELARVTVVSSSLQVVFDSFVKPDNDVIDYNTRFSGISEADVKSSSSSLRDVQAVLLSFINADTILIGHGLENDLAALKIIHSTVVDTSVVFPHRLGLPHKRELNSLTADYLRRIIQESVEGHDTREDATACMELMLWRVKEDSKVKRW", "length": 1216, "header": "tr|A0AC58JBI7-1|A0AC58JBI7_DANRE Computationally mapped isoform of Uncharacterized protein isoform X1 OS=Danio rerio OX=7955 GN=zgc:152968 PE=3 SV=1 CANONICAL=B8JII5-1" }, "locus": {} }, { "isoform_ac": "B8JII5-1", "url": "https://www.uniprot.org/uniprotkb/B8JII5/entry#B8JII5-1", "sequence": { "sequence": "MFPSTALFDEIDCPFLQSGRCQRPYCLYNHSKDSSSCVMNTTGLGDPKVTSANGSSHTTEDNYACLEELERINKEIEAVRSEVEKEQKRLSQYQTSQSLTQTGQCSGKYLRTTKSRPKDQNGNHLKSKKPVCSTSGQKYVVDRARPKTDLEYDPCSNFSADLLSSSSAECKLKSSDKVDIDHGLKSKQTGKNVQPLSSHFDDSEDEGTLVIDIPSLTKDHRKHKPKQESAIIKTPHVLERNGAVNNDLSNQQTNPNQHKEKSSDGLPSHEMKRTVSDQENARTLVKPMMITEEQESSEGELVIDVSQFEDEHKLPQQRESKNKELLDLPKLCPVSNAPAEHYKEANDGQIIKGITMANHPGKDIEPFLEDLREEPVAEPNNFTNINMETFVKQKEEKAHNLENVLDDISTCLNNMRSQSDELKTIQDVKMLPVNSVYGDECISSQSPRSALQNLTSREPQNSSISGYALKSENVSSKDISQIHQQYFPMVSSQSLPSPLHKAEEHRFLGPPHSQSLTETSWVTLQSSHGEPFVQNTPAYVSEIDFGVVSAPSNSQLNPRTVESIEKLPTSNVSYSAACDMTVPSQTFATMAGNNNEPIVVDSSSDAELRYSDLDLSDTDPMEECYRIFMEANQSEAPVVQCDAPDKVGTEMKSNPVALLKKRVAHVAKFEPASKSKAQIIVPLQEGTSHLNVPSRSQLCQRRAAILTAAVKGCQSQVINSAPKKVYTSNVHQIHQSAVQNSCVGIIPVGATLQLGTNLHFIVPEGNCALPLTLIPTTMSVQRPPHPSPPVQLAPAQHPTQPANYTPAKRQAICLSTQDSTQQRFKYHRPSEAQNSALHSQPNVMGVKRKAKVHHEVGAKVPHDVRQRYVNLFVEEFLKSSVTVQDAFEKALAEEKIVYDRSINKLKYLSIAVNALKRLKNQNILPAKAPSERDQHVSRGNVPLNTQALQGPGDLTLFEQLKEHILSEDLLQVNNFPRKHQDKADFAIQYGDTKKGISDPLKRICCRCGATFSVDRSGKHTRREECNYHYGKVIENRVPGGVETRYSCCENAVGSPGCQVFNLHVHDAVSLQGFVSSLHQSAVGKTCPGIYAIDTQTCYTTQGLELARVTVVSSSLQVVFDSFVKPDNDVIDYNTRFSGISEADVKSSSSSLRDVQAVLLSFINADTILIGHGLENDLAALKIIHSTVVDTSVVFPHRLGLPHKRELNSLTADYLRRIIQESVEGHDTREDATACMELMLWRVKEDSKVKRW", "length": 1251, "header": "tr|B8JII5-1|B8JII5_DANRE Isoform 1 of Uncharacterized protein LOC564848 OS=Danio rerio OX=7955 GN= PE=3 SV=1 CANONICAL=B8JII5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification of direct T-box target genes in the developing zebrafish mesoderm.", "journal": "Development", "date": "2009", "authors": "Garnett Aaron T, Han Tina M, Gilchrist Michael J, Smith James C, Eisen Michael B, Wardle Fiona C, Amacher Sharon L", "evidence": [ { "database": "UniProtKB", "id": "B8JII5", "url": "https://www.uniprot.org/uniprotkb/B8JII5" } ], "reference": [ { "type": "PubMed", "id": "19158186", "url": "https://glygen.org/publication/PubMed/19158186" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8JII5", "url": "https://www.uniprot.org/uniprotkb/B8JII5" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:564848", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564848", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "rRNA 3'-end processing", "id": "GO:0031125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031125", "evidence": [ { "database": "UniProtKB", "id": "B8JII5", "url": "https://www.uniprot.org/uniprotkb/B8JII5" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B8JII5", "url": "https://www.uniprot.org/uniprotkb/B8JII5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "B8JII5", "url": "https://www.uniprot.org/uniprotkb/B8JII5" } ], "pmid": "" }, { "name": "exonuclease activity", "id": "GO:0004527", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004527", "evidence": [ { "database": "UniProtKB", "id": "B8JII5", "url": "https://www.uniprot.org/uniprotkb/B8JII5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 157, "end_pos": 159, "annotation": "n_glycosylation_sequon" }, { "start_pos": 29, "end_pos": 31, "annotation": "n_glycosylation_sequon" }, { "start_pos": 381, "end_pos": 383, "annotation": "n_glycosylation_sequon" }, { "start_pos": 40, "end_pos": 42, "annotation": "n_glycosylation_sequon" }, { "start_pos": 453, "end_pos": 455, "annotation": "n_glycosylation_sequon" }, { "start_pos": 461, "end_pos": 463, "annotation": "n_glycosylation_sequon" }, { "start_pos": 473, "end_pos": 475, "annotation": "n_glycosylation_sequon" }, { "start_pos": 53, "end_pos": 55, "annotation": "n_glycosylation_sequon" }, { "start_pos": 571, "end_pos": 573, "annotation": "n_glycosylation_sequon" }, { "start_pos": 632, "end_pos": 634, "annotation": "n_glycosylation_sequon" }, { "start_pos": 803, "end_pos": 805, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8JII5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JII5" }, { "id": "SM00479", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00479" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Exonuclease", "eco_id": "ECO_0000259", "start_pos": 1088, "end_pos": 1247, "start_aa": "Gly", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 157, "end_pos": 159 }, { "start_pos": 29, "end_pos": 31 }, { "start_pos": 381, "end_pos": 383 }, { "start_pos": 40, "end_pos": 42 }, { "start_pos": 453, "end_pos": 455 }, { "start_pos": 461, "end_pos": 463 }, { "start_pos": 473, "end_pos": 475 }, { "start_pos": 53, "end_pos": 55 }, { "start_pos": 571, "end_pos": 573 }, { "start_pos": 632, "end_pos": 634 }, { "start_pos": 803, "end_pos": 805 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JII7-1", "uniprot_ac": "B8JII7", "uniprot_id": "B8JII7_DANRE", "mass": { "chemical_mass": 36983.0, "monoisotopic_mass": 36983.0 }, "refseq": { "ac": "NP_001009985", "name": "ras association domain-containing protein 4a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009985" }, "gene_names": [ { "name": "rassf4a", "type": "recommended", "evidence": [ { "id": "B8JII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JII7" } ] }, { "name": "rassf4a", "type": "synonym", "evidence": [ { "id": "NP_001009985", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009985" } ] }, { "name": "rassf4", "type": "synonym", "evidence": [ { "id": "NP_001009985", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009985" }, { "id": "B8JII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JII7" } ] }, { "name": "zgc:92261", "type": "synonym", "evidence": [ { "id": "NP_001009985", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009985" }, { "id": "B8JII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JII7" } ] } ], "protein_names": [ { "name": "Ras association (RalGDS/AF-6) domain family member 4a", "type": "synonym", "evidence": [ { "id": "NP_001009985", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009985" } ] }, { "name": "Ras association (RalGDS/AF-6) domain family member 4", "type": "synonym", "evidence": [ { "id": "NP_001009985", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009985" } ] }, { "name": "Ras association domain-containing protein 4a", "type": "synonym", "evidence": [ { "id": "B8JII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JII7/entry#names_and_taxonomy" } ] }, { "name": "ras association domain-containing protein 4a", "type": "synonym", "evidence": [ { "id": "NP_001009985", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009985" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01002882.1, SRR32588730.25201831.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1, EH583810.1 and EH434513.1. On or before Feb 13, 2016 this sequence version replaced XP_005156880.1, NP_001009985.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001009985", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009985" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JII7", "url": "https://www.uniprot.org/uniprotkb/B8JII7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rassf4a", "url": "https://www.uniprot.org/uniprotkb/B8JII7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050102-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050102-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000012460", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000012460", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd17222", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd17222", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd21894", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21894", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "494494", "url": "https://www.ncbi.nlm.nih.gov/gene/494494", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000159", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000159", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011524", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011524", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR029071", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029071", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033614", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033614", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033622", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033622", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:494494", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:494494", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "RMCERQT", "url": "https://omabrowser.org/oma/group/RMCERQT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JII7", "url": "https://www.orthodb.org/?gene=B8JII7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22738", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22738", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22738:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22738:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00788", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00788", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF16517", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF16517", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001009985", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001009985", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JII7", "url": "https://www.uniprot.org/uniprotkb/B8JII7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JII7-1", "url": "https://www.uniprot.org/uniprotkb/B8JII7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050102-3", "url": "https://zfin.org/ZDB-GENE-050102-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDPVKTSYVRLNEEKVIAKSDILSLLKTYNCYHEGKSFQLRIREEEGELIVEGLLNISWGLRRPIRLQMHDDNERFRYACMGAWRSESPESSRNENAKHQFCSEPNNNKISATTLSNVDGVEEDIPQLLRTRSDASFVNIQRRSKLHSISDSQRIKRHRFSINGHFYNHKTSVFTPSYGSVTNVRVNSNLTTQQVLNLLLNKFRVENKIDEFGLYLVHESGERTKLKDTEYPLVSRLLHGPCEKIARIFIMETDLGEEITYDVAQYIKFEMPVLDSFIKKLKEEEEREILKLTRKYRMLKSVILQKLDGISENASYV", "length": 317, "header": "tr|B8JII7-1|B8JII7_DANRE Isoform 1 of Ras association domain-containing protein 4a OS=Danio rerio OX=7955 GN=rassf4a PE=4 SV=1 CANONICAL=B8JII7-1" }, "isoforms": [ { "isoform_ac": "B8JII7-1", "url": "https://www.uniprot.org/uniprotkb/B8JII7/entry#B8JII7-1", "sequence": { "sequence": "MDPVKTSYVRLNEEKVIAKSDILSLLKTYNCYHEGKSFQLRIREEEGELIVEGLLNISWGLRRPIRLQMHDDNERFRYACMGAWRSESPESSRNENAKHQFCSEPNNNKISATTLSNVDGVEEDIPQLLRTRSDASFVNIQRRSKLHSISDSQRIKRHRFSINGHFYNHKTSVFTPSYGSVTNVRVNSNLTTQQVLNLLLNKFRVENKIDEFGLYLVHESGERTKLKDTEYPLVSRLLHGPCEKIARIFIMETDLGEEITYDVAQYIKFEMPVLDSFIKKLKEEEEREILKLTRKYRMLKSVILQKLDGISENASYV", "length": 317, "header": "tr|B8JII7-1|B8JII7_DANRE Isoform 1 of Ras association domain-containing protein 4a OS=Danio rerio OX=7955 GN=rassf4a PE=4 SV=1 CANONICAL=B8JII7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification of vascular and hematopoietic genes downstream of etsrp by deep sequencing in zebrafish.", "journal": "PLoS ONE", "date": "2012", "authors": "Gomez Gustavo, Lee Jae-Hyung, Veldman Matthew B, Lu Jing, Xiao Xinshu, Lin Shuo", "evidence": [ { "database": "UniProtKB", "id": "B8JII7", "url": "https://www.uniprot.org/uniprotkb/B8JII7" } ], "reference": [ { "type": "PubMed", "id": "22438865", "url": "https://glygen.org/publication/PubMed/22438865" } ] }, { "title": "Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.", "journal": "J. Immunol.", "date": "2014", "authors": "Briolat Val\u00e9rie, Jouneau Luc, Carvalho Ralph, Palha Nuno, Langevin Christelle, Herbomel Philippe, Schwartz Olivier, Spaink Herman P, Levraud Jean-Pierre, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "B8JII7", "url": "https://www.uniprot.org/uniprotkb/B8JII7" } ], "reference": [ { "type": "PubMed", "id": "24683187", "url": "https://glygen.org/publication/PubMed/24683187" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JII7", "url": "https://www.uniprot.org/uniprotkb/B8JII7" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:494494", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:494494", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A3Q1LR92-1", "protein_name": "Ras association domain family member 4", "gene_name": "RASSF4", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MKEDCPPSSHVPISDSKSILKSELLSLLKTYNCYHEGKSSQLRRREEEGALIIEGLLNISWGLKRPIRLQIQDDRERVHLSWTPGQSSCHSKEPPVQDGRVTAQEPSSQAGPQEESSRDRSEPVEEDEETPQLLRTKSDAACVIQRRPRSRAPGEAQRTRRHRFSINGHFYNHKTSVFTPAYGSMTNVRVNSTMTTLQVLTLLLNKFRVENGPSEFALYVVHESGERTKLKDCEYPLIARILHGPCEKIARIFLMEADLGEEVPHDVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEAK", "length": 318 }, "evidence": [ { "id": "B8JII7", "url": "https://omabrowser.org/oma/group/B8JII7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q566C5-1", "protein_name": "Ras association domain-containing protein 4", "gene_name": "Rassf4", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKEDCSPSSHVPISDSKFILKSELLSLLKTYNCYHEGRSFQLRHREEEGTLIIEGLLNIAWGLRRPIRLQMQDDRERVHLPSATWVPERLSYLQKDASPQDSKVPAEEPSTQPANKGEVSRDGSGPLQEEEEEVPQLMRTKSDASCIIQRRCKSRAPGEAQKIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTQQVLTLLLNKFRVEDGPSEFALYTVHESGEQTKLKDCEYPLISRILHGPCEKIVKIFLMEADLSEEVPHDVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMQQRLEQLVEAK", "length": 322 }, "evidence": [ { "id": "HGNC:20793", "url": "https://alliancegenome.org/gene/HGNC:20793#orthology", "database": "AGR" }, { "id": "B8JII7", "url": "https://omabrowser.org/oma/group/B8JII7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8CB96-1", "protein_name": "Ras association domain-containing protein 4", "gene_name": "Rassf4", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKEACSSSSHVPVSDSKYILKSELLSLLKTYNCYHEGRSFQLRHREEEGTLIIEGLLNIAWGLRRPIRLQMQDDRERVHLPSATWVPERLSYLQKEASPQDSKVPTEEPGTQPANKAEVSGDSSGALEGEEEEVPQLMRTKSDASCIIQRRSKSRAPSEAQKIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTQQVLTLLLNKFRVEDGPSEFALYTVHESGEQTKLKDCEYPLISRILHGPCEKIVKIFLMEADLSEEVPHDVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEAK", "length": 322 }, "evidence": [ { "id": "HGNC:20793", "url": "https://alliancegenome.org/gene/HGNC:20793#orthology", "database": "AGR" }, { "id": "B8JII7", "url": "https://omabrowser.org/oma/group/B8JII7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9H2L5-1", "protein_name": "Ras association domain-containing protein 4", "gene_name": "RASSF4", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKEDCLPSSHVPISDSKSIQKSELLGLLKTYNCYHEGKSFQLRHREEEGTLIIEGLLNIAWGLRRPIRLQMQDDREQVHLPSTSWMPRRPSCPLKEPSPQNGNITAQGPSIQPVHKAESSTDSSGPLEEAEEAPQLMRTKSDASCMSQRRPKCRAPGEAQRIRRHRFSINGHFYNHKTSVFTPAYGSVTNVRVNSTMTTLQVLTLLLNKFRVEDGPSEFALYIVHESGERTKLKDCEYPLISRILHGPCEKIARIFLMEADLGVEVPHEVAQYIKFEMPVLDSFVEKLKEEEEREIIKLTMKFQALRLTMLQRLEQLVEAK", "length": 321 }, "evidence": [ { "id": "HGNC:20793", "url": "https://alliancegenome.org/gene/HGNC:20793#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050102-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050102-3#orthology", "database": "AGR" }, { "id": "B8JII7", "url": "https://omabrowser.org/oma/group/B8JII7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VCQ7-1", "protein_name": "Ras association family member", "gene_name": "Rassf", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MWKCHKCGKPVYFAERKQSIGYDWHPECLRCEECGKRLNPGQHAEHKSVPYCHVPCYGALFGPQLFGHGTRVESHKSYGVKGAQKPTGAQANGPPLPRDHLESKLKVYNQFYDNKSLEIRSREVNNRLVLEGALRVYWGVQGVIHLKEDDDQRILVRKRNSCRVSKAANESSSDKENEASESLAPPTTTTAEVDQLSTDVSLSESMTFDSCSLNEISELPTTPEDASANTTANSKEQTNGNVCNDDEDTTTTDSSGTLVEAPTASTSCVSSTLPSKLDRLEKLDWDDIDDLLQVERRHNDKDRIYETMPVKLPSSQSSSDSSPSKTSTETTTTTESSSTQSASTNTSSTDDFMTATGSLTANTNTQNTTTVSTTETSLDNFETCDDATLKPIDFEDFKRSVHQDYVNGANSFTEPNEGTLKRNQPIDPSRIHDSLKLYGENSAMSKSFNCEHALRSIDPTLINDTMNLRSSVGSPHSAQRQYALQKSGSATVTSRDQKKPYQQGRQLFEKGINRSKSGPSCFVYSDSDDDDEATLRPQRMATIRRSDIPQRYIQIQMDCYPKENVAAASEGESSRADAPSITSGAAAGDELTQTEDLYTASEGVDGPDGDGSAGLHVTEDGVVLRRPPRTGASAIKRRSGNRRSRTKLKRRCSINGHYYNRETSFFTPPYGSQMSVWVSSMVTTTEVINLVLEKYKVDSSPGNFSLFIVRDNGEQKRLKDDEYPLITRVTLGPHEDVARIFLVDSRKTDEISNEVAQFLNLSLPECRAILERYDQELAREVAKIKERYAELRRRIVSRMESLKVHL", "length": 806 }, "evidence": [ { "id": "HGNC:20793", "url": "https://alliancegenome.org/gene/HGNC:20793#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "B8JII7", "url": "https://www.uniprot.org/uniprotkb/B8JII7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" }, { "start_pos": 313, "end_pos": 315, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8JII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JII7" }, { "id": "PS50200", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50200" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Ras-associating", "eco_id": "ECO_0000259", "start_pos": 167, "end_pos": 255, "start_aa": "Tyr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "B8JII7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JII7" }, { "id": "PS50951", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50951" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SARAH", "eco_id": "ECO_0000259", "start_pos": 263, "end_pos": 310, "start_aa": "Val", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 }, { "start_pos": 313, "end_pos": 315 }, { "start_pos": 56, "end_pos": 58 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JIN4-1", "uniprot_ac": "B8JIN4", "uniprot_id": "B8JIN4_DANRE", "mass": { "chemical_mass": 130580.0, "monoisotopic_mass": 130580.0 }, "refseq": { "ac": "NP_001139034", "name": "dynein axonemal assembly factor 9", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139034" }, "gene_names": [ { "name": "dnaaf9", "type": "recommended", "evidence": [ { "id": "B8JIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JIN4" } ] }, { "name": "dnaaf9", "type": "synonym", "evidence": [ { "id": "NP_001139034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139034" } ] }, { "name": "si:ch211-194c3.5", "type": "synonym", "evidence": [ { "id": "NP_001139034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139034" }, { "id": "B8JIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JIN4" } ] } ], "protein_names": [ { "name": "Dynein axonemal assembly factor 9", "type": "synonym", "evidence": [ { "id": "B8JIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JIN4/entry#names_and_taxonomy" } ] }, { "name": "dynein axonemal assembly factor 9", "type": "synonym", "evidence": [ { "id": "NP_001139034", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139034" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01035736.1, GDQH01018110.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000013.1. On Mar 5, 2009 this sequence version replaced XP_683859.3.", "evidence": [ { "database": "RefSeq", "id": "NP_001139034", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139034" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JIN4", "url": "https://www.uniprot.org/uniprotkb/B8JIN4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "dnaaf9", "url": "https://www.uniprot.org/uniprotkb/B8JIN4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-63", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000079056", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000079056", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22936", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22936", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "556058", "url": "https://www.ncbi.nlm.nih.gov/gene/556058", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR040342", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040342", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056414", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056414", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056498", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056498", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057478", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057478", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058843", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058843", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR058844", "url": "https://www.ebi.ac.uk/interpro/entry/IPR058844", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556058", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556058", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "HPAGEKW", "url": "https://omabrowser.org/oma/group/HPAGEKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JIN4", "url": "https://www.orthodb.org/?gene=B8JIN4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR33664", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33664", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR33664:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR33664:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF23281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23319", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23319", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25203", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25203", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25204", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25204", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF26246", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26246", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001139034", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139034", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JIN4", "url": "https://www.uniprot.org/uniprotkb/B8JIN4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JIN4-1", "url": "https://www.uniprot.org/uniprotkb/B8JIN4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-63", "url": "https://zfin.org/ZDB-GENE-090313-63", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLSKYQTTNMAAIRKNKSSIMTAAVSCSRLRQVQALLRDDVNTAPDGILCSLGIDSRYNEGCSELASYLFCGLYNHNHFDMEQIPEDFPEEVLDDVIILIKAECVHLYCNPVNYGYLLPYVSHWRNLQLHCLTETEYEDEEVAEEFKISSFVSMVQDCHCIGIPYSSHGHVQKFDMFMLEKWPIIQAFALEGIGAGLFFTMKYKLKDVSQRLWQVYSRLDPVSLDCLLNEDLQLFERQWSCLFSSMEIESALSMQELSEAQVAEPFRTYYSHGLISSNITDKSKSRQPFVLFGSHSTKEDLESYCFTFPSEGHQVRNTGPSGGVAKHMLLQCVAPKGPLACARTYFFGNTHVPYLGNNNTQQRRTDLQVLSHIYSAAIQSVLAGIKCFSINSSASKAKDVADQTFQLALESFGLIQYKGALRSKAVFSIQAVNNKGSIVPLSDEDSHFLVKTASMMVYDIPDLQCGGNLGSVVFSESFLESSVYIQQRDGALSSDSCFTVLTSSIPRYVSWLVDEAEVRMSEQAQHLLKAEDSTCLGIPITVRDSAYMFSNSLLSTPEEGKLVFFSEGILFVHPHHGSITLSMSHINSIKLYDGASLSDISMLFIEYQTSLLPHLPFPLHSSDFSLAVALLPRTKSYKSFYSQVLPAWRKSESGLRVQHVLNDQLSPEHKSMYFRLLKLHETHAVPANHRVVLRTAYPQLPEQDRFLQHFAISSSVDEESVCSDHLSTVFSDTIPESTKPEPKKKVVLTIIAGLPGSHKENLCDFLMEVNQNSSRWEVFCPALEGSGEFSASHLQRFLSSLLAKQRETDMNSFRVVLLIPGYTDIMDVIQAITAHPDPQVHSQVTVGAVSACVNPLTSFIKHRLLFPKLLEQCSQGIVSNVVFTGLTMEQKHPLLQHMQQLIRAANLSTAFISAEKGAVRRTEDLRLILNDSSFSQPHMVNARYLLYPGWWEGRFVSGSGSLSMSQHRVEFSRPLERALFLQRCKALKSSLKPSPFTGNIYHISGKVLFSDNDRQMVVNCNSISGNVTVAPDQGTHHGLWTTNNCYLMFHGVGLTQEGLKDWLRHCAKQKIVKKVKKNQRTLTTEEIKYIHLKRHLDPLPPGYFYNGHHFVSFFGEKQNFHPLMDRFIDEYVQDANKEIERFNREVDLQPHADLFDP", "length": 1157, "header": "tr|B8JIN4-1|B8JIN4_DANRE Isoform 1 of Dynein axonemal assembly factor 9 OS=Danio rerio OX=7955 GN=dnaaf9 PE=4 SV=1 CANONICAL=B8JIN4-1" }, "isoforms": [ { "isoform_ac": "B8JIN4-1", "url": "https://www.uniprot.org/uniprotkb/B8JIN4/entry#B8JIN4-1", "sequence": { "sequence": "MLSKYQTTNMAAIRKNKSSIMTAAVSCSRLRQVQALLRDDVNTAPDGILCSLGIDSRYNEGCSELASYLFCGLYNHNHFDMEQIPEDFPEEVLDDVIILIKAECVHLYCNPVNYGYLLPYVSHWRNLQLHCLTETEYEDEEVAEEFKISSFVSMVQDCHCIGIPYSSHGHVQKFDMFMLEKWPIIQAFALEGIGAGLFFTMKYKLKDVSQRLWQVYSRLDPVSLDCLLNEDLQLFERQWSCLFSSMEIESALSMQELSEAQVAEPFRTYYSHGLISSNITDKSKSRQPFVLFGSHSTKEDLESYCFTFPSEGHQVRNTGPSGGVAKHMLLQCVAPKGPLACARTYFFGNTHVPYLGNNNTQQRRTDLQVLSHIYSAAIQSVLAGIKCFSINSSASKAKDVADQTFQLALESFGLIQYKGALRSKAVFSIQAVNNKGSIVPLSDEDSHFLVKTASMMVYDIPDLQCGGNLGSVVFSESFLESSVYIQQRDGALSSDSCFTVLTSSIPRYVSWLVDEAEVRMSEQAQHLLKAEDSTCLGIPITVRDSAYMFSNSLLSTPEEGKLVFFSEGILFVHPHHGSITLSMSHINSIKLYDGASLSDISMLFIEYQTSLLPHLPFPLHSSDFSLAVALLPRTKSYKSFYSQVLPAWRKSESGLRVQHVLNDQLSPEHKSMYFRLLKLHETHAVPANHRVVLRTAYPQLPEQDRFLQHFAISSSVDEESVCSDHLSTVFSDTIPESTKPEPKKKVVLTIIAGLPGSHKENLCDFLMEVNQNSSRWEVFCPALEGSGEFSASHLQRFLSSLLAKQRETDMNSFRVVLLIPGYTDIMDVIQAITAHPDPQVHSQVTVGAVSACVNPLTSFIKHRLLFPKLLEQCSQGIVSNVVFTGLTMEQKHPLLQHMQQLIRAANLSTAFISAEKGAVRRTEDLRLILNDSSFSQPHMVNARYLLYPGWWEGRFVSGSGSLSMSQHRVEFSRPLERALFLQRCKALKSSLKPSPFTGNIYHISGKVLFSDNDRQMVVNCNSISGNVTVAPDQGTHHGLWTTNNCYLMFHGVGLTQEGLKDWLRHCAKQKIVKKVKKNQRTLTTEEIKYIHLKRHLDPLPPGYFYNGHHFVSFFGEKQNFHPLMDRFIDEYVQDANKEIERFNREVDLQPHADLFDP", "length": 1157, "header": "tr|B8JIN4-1|B8JIN4_DANRE Isoform 1 of Dynein axonemal assembly factor 9 OS=Danio rerio OX=7955 GN=dnaaf9 PE=4 SV=1 CANONICAL=B8JIN4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JIN4", "url": "https://www.uniprot.org/uniprotkb/B8JIN4" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:556058", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556058", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZVN5-1", "protein_name": "Dynein axonemal assembly factor 9", "gene_name": "Dnaaf9", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDSFAPQQPGLSRARLAGTFGRGAASVSCSRLRQVQSVLTQSSKSQPDGILCILGIDSRYNEGCRELANYLLFGLYSQNTTDFEKTGFSEEILDDVIMLIKSDSVHLYCNPVNYRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKISSFVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYELQDVSLNLWNVYSRMDPMSLENMLSKDLAVFEHQWTSFFANFDIEIPFLLELSESQAGEPFRSYFSHGMISSHVTENSPHRQPFVLFGTHSTRDNLRTGSFNFPSEGHLVRNTGPAGSIAKHMVAQCVSPKGPLACSRTYFFGATHVPYLGDDEKLPRTTEQIRLLSQVYAAVTEAVLAAIACYAKTCSLAKAKEVAEQTLESGLVFTELVPFKAELRSKVAFHIHAVNNQGRIVPLNNEDSLSFVKTASMSVYDIPDVLGGGGCLGSVVFSESFLTSQILVKEKDGTITPETSYIILTAAIPRFCSWLVEDNEVKLCEKTLQATKGDDCFLGTLLTGGKGAYLYSNSLQSRPEEGNVYFFSGGLLFSHRHHASVVISKDHMNSVSFYDGDSTSVVAALLIDFRSSILPHLPVHFHGSSNFLMIALFPRSKIYQAFYSEVFSPWQQQDNSGLSLKVIQEDGLSVEQKKLYSNAQKLFSALSHPAQDWSSPKLLSAKLPELDRFLQHFALGSIGQEPVMRAHLLSLLQQAETSPTHRLESDKVVISIVTGLPGCHASKLCAFLVTLHKEYGRWMVYRQVMDSSECFHAAHFQKYLSSALEAQQNRSARQSAYIRKKTRLLVALQGYTDVIDVVQALQTHPDPNVKSYFTIGAVTVCVEPLSCYMEHRFLFPKCLDQCSQGVVSNVVFTSHTTEQRHPLLVELQTLIRASNPTAAFILAENGIVTRNEDIELILSENSFSSPQMLRSRYLLFPGWYEGKFDAGSVFPLMVQICVWFDRPLEKTRFVTKCKAIQSSLKPSPFSGNIYHILGKVKFSDSEKTMEVCHNTLTNSLTIVPVLEGPTPPPNSRSTPQDNGQPECYLVFIGCSLKEDSLKDWLRQSAKQRPQRKALKTRGMLTQQEIRNIHVKRHLDPLPAGYFYNGTQFVNFFGDKTDFHPLMDQFMNDYVEEANREIERYNRELEQQEYRDLFEQKP", "length": 1175 }, "evidence": [ { "id": "MGI:1923029", "url": "https://alliancegenome.org/gene/MGI:1923029#orthology", "database": "AGR" }, { "id": "HGNC:17721", "url": "https://alliancegenome.org/gene/HGNC:17721#orthology", "database": "AGR" }, { "id": "B8JIN4", "url": "https://omabrowser.org/oma/group/B8JIN4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BK28-1", "protein_name": "Dynein axonemal assembly factor 9", "gene_name": "DNAAF9", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MDAYPPHRVGLTRARSLGGLGRGSPSVSCSRLRQVQRILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLLGLYNQNASDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNYRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKIASFVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPVVQAFALEGIGGDGFFTMKYELQDVSLNLWNVYSKMDPVSLESLLSEDLVAFEYQWTSFFANFDTEIPFLLELSESQAGEPFRSYFSHGMISSHITENSPNRQPFVLFGNHSTRENLNAGNFNFPSEGHLVRSTGPSGSFARHMVVQCVSPKGPLACSRTYFFGATHVPYLGDDNKLPKKTEQIRLLSQVYATVIEAVLAAIACYAKTSSLIKAKEVAEQTLGSGLNSVELMQFKATLRSKMAFHIHAVNNQGRIVPLDSEDSLYFVKTACMAIYDIPDLLGGRGCLGSVVFSESFLTSQILVKEKDGTVITETSFIILTAAIPRFCSWLVEDIEVKLSEKTQQSVLGDECFLGTFLTRGEGAYLYSSNSQSLPEEGKVHFFSNGLLFSDRHHGNIIISKDHMNSILFYDGDSTSVVAALLIDFKSSLLPHLPVYFHGSSNFLMIVLFPKSKIYQTFYSEVFSPWQQQTNSGLSLKVIQEDGLSVEQKRLHSRAQKLFSVLSHSAGEKQSPLKLLSAKLPELNGFLQHFAVSSISQEPVVRTHLPVLLQQAEINPIHRVENDKVIISIVTGLPGCHASELCAFLVTLHKEYGRWMVYRQVMDSSECFHAAHFQRYLSSALEAQQNRSARQSAYVRKKTRLLVVLQGYTDVIDVVQALQTHPDSNVKSCFTIGTITVCVEPLSCYMEHRFLFPKFLDQCSQGLVSNVVFTSHTMEQRHPLLVQLQSLIRAANPSASFILAENGIVTRNEDIELILSENSFSSPQMLRSRYLMYPGWYEGKFDAGSVFPLMVQICVWFGRPLEKTRFVAKCKAIQSSIKPSPFSGNIYHILGKVKFSDSERMMEVCHNTLANSLSIVPVLEGPTPPPDSRTSPQSSSGQQECYLVFIGCSLKEESVKDWLRQSAKQKPQRKALKTRGMLTQQEIRNIHVKRHLDPLPAGYFYNGTQFVNFFGDKTDFHPLMDQFMNDYVEEANREIEKYNRELEQQEYHDLFEQKP", "length": 1177 }, "evidence": [ { "id": "B8JIN4", "url": "https://omabrowser.org/oma/group/B8JIN4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q5TEA3-1", "protein_name": "Dynein axonemal assembly factor 9", "gene_name": "DNAAF9", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MDVYPPRRQGLPRARSPGGSSRGSPSVSCSRLRQVQSILTQSSKSRPDGILCILGIDSRYNEGCRELANYLLFGLYNQNTSDFEKTGFSEEVLDDVIILIKSDSVHLYCNPVNFRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKITSFVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYELQDVSLNLWNVYSKMDPMSLESLLSDDLVAFEHQWTSFFANFDTEIPFLLELSESQAGEPFRSYFSHGMISSHITENSPNRQPFVLFGNHSTRENLNAGNFNFPSEGHLVRSTGPGGSFAKHMVAQCVSPKGPLACSRTYFFGATHVPYLGGDSKLPKKTEQIRLLSQIYAAVIEAVLAGIACYAKTSSLTKAKEVAEQTLGSGLDSFELIPFKAALRSKMTFHIHAVNNQGRIVPLDSEDSLSFVKTACMAVYDIPDLLGGNGCLGSVVFSESFLTSQILVKEKDGTVTTETSSVVLTAAVPRFCSWLVEDNEVKLSEKTQQAVRGDESFLGTYLTGGEGAYLYSSNLQSWPEEGNVHFFSSGLLFSHCRHRSIIISKDHMNSISFYDGDSTSTVAALLIDFKSSLLPHLPVHFHGSSNFLMIALFPKSKIYQAFYSEVFSLWKQQDNSGISLKVIQEDGLSVEQKRLHSSAQKLFSALSQPAGEKRSSLKLLSAKLPELDWFLQHFAISSISQEPVMRTHLPVLLQQAEINTTHRIESDKVIISIVTGLPGCHASELCAFLVTLHKECGRWMVYRQIMDSSECFHAAHFQRYLSSALEAQQNRSARQSAYIRKKTRLLVVLQGYTDVIDVVQALQTHPDSNVKASFTIGAITACVEPMSCYMEHRFLFPKCLDQCSQGLVSNVVFTSHTTEQRHPLLVQLQSLIRAANPAAAFILAENGIVTRNEDIELILSENSFSSPEMLRSRYLMYPGWYEGKLNAGSVYPLMVQICVWFGRPLEKTRFVAKCKAIQSSIKPSPFSGNIYHILGKVKFSDSERTMEVCYNTLANSLSIMPVLEGPTPPPDSKSVSQDSSGQQECYLVFIGCSLKEDSIKDWLRQSAKQKPQRKALKTRGMLTQQEIRSIHVKRHLEPLPAGYFYNGTQFVNFFGDKTDFHPLMDQFMNDYVEEANREIEKYNQELEQQEYHDLFELKP", "length": 1177 }, "evidence": [ { "id": "MGI:1923029", "url": "https://alliancegenome.org/gene/MGI:1923029#orthology", "database": "AGR" }, { "id": "HGNC:17721", "url": "https://alliancegenome.org/gene/HGNC:17721#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-63#orthology", "database": "AGR" }, { "id": "B8JIN4", "url": "https://omabrowser.org/oma/group/B8JIN4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TT23-1", "protein_name": "Dynein axonemal assembly factor 9", "gene_name": "Dnaaf9", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MDSFDPQQLGLSPARFAGTFGSGAASVSCSRLRQVQSVLTQSSKSQPDGILCILGIDSRYNEGCRELANYLLFGLYSQNATDFEKTGFSEEILDDVILLIKSDSVHLYCNPVNYRYLLPYVAHWRNLHFHCMTENEYEDEEAAEEFKISSFVDMVRDCSRIGIPYSSQGHLQIFDMFVVEKWPIVQAFALEGIGGDGFFTMKYELQDVSLSLWNVYSRMDPASLENMLSEDLAVFEHQWTSFFANFDTEIPFLLELSESQAGEPFRSYFGHGMLSSHITENSPHRQPFVLFGNHSTRDNLSAGSFNFPSEGHLVRNTGPAGSFAKHMVAQCVSPKGPLACSRTYFFGATHVPYLGDNEKLPRTTEQIRLLSQIYAAVIEAVLAGIACYAKTCSLAKAKEVAEHTLESGLVFTELVPFKADLRSKVTFHIHAVNNQGRIVPLNNEDSLSFVKTARMTVYDIPDLLGGGGGGCLGSVVFSESFLTSRILVKEKDGTITPETSYIILTAAIPRFCSWLVEDSEIKLSEKTLQATKGDDCCLGTLLTGGKGAYLYSNSPQSGPEEGSAYFFSGGLLFSHRHHGSIVIAKEHVDAFSFYDGDSTSVVAALLIHFRSSILPHLPVHFHGSSNFLMLALFPKSKIYQAFYSEVFSPWQQQDNSGLSLKVIQEDGLSAEQKRLHSNAQKLFSALSPPAQDWSSPKLLSGKLPELDRFLQHFAIGSIGQEPVMRAHLVGLLQQPEMSPAHEVESDKVVISIVTGLPGCHASKLCAFLITLHKEYGRWMVYRQIMDSSECFHAAHFQKYLSSALEAQQNRSARQSAYIRKKTRLLVVLQGYTDVIDVVQALQTHPDPNVRSYFTIGAVTVCVEPLSCYMEHRFLFPKCLDQCSQGVVSNVVFTSHTAEQKHPLLVQLQTLIRASNPTAAFILAENGIVTRNEDIELILSENSFSSPQMLRSRYLLFPGWYEGKFDAGSVFPLMVQICVWFDCPLEKTRFVSRCRAIQSSIKPSPFSGNIYHILGKVKFSDSEKTMEVCHNTLTNSLTIVPVLEGPTPPPNSRSSPQDNGQPECYLVFIGCSLKEDSLKDWLRQSAKQRPQRKALKTRGMLTQQEIKNIHVKRHLDPLPAGYFYNGTQFVNFFGDKTDFHPLMDQFMNDYVEEANREIERYNRELEQQEYRDLFEQKPKP", "length": 1179 }, "evidence": [ { "id": "MGI:1923029", "url": "https://alliancegenome.org/gene/MGI:1923029#orthology", "database": "AGR" }, { "id": "HGNC:17721", "url": "https://alliancegenome.org/gene/HGNC:17721#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-63", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-63#orthology", "database": "AGR" }, { "id": "B8JIN4", "url": "https://omabrowser.org/oma/group/B8JIN4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 1026, "end_pos": 1028, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 278, "end_pos": 280, "annotation": "n_glycosylation_sequon" }, { "start_pos": 358, "end_pos": 360, "annotation": "n_glycosylation_sequon" }, { "start_pos": 391, "end_pos": 393, "annotation": "n_glycosylation_sequon" }, { "start_pos": 772, "end_pos": 774, "annotation": "n_glycosylation_sequon" }, { "start_pos": 906, "end_pos": 908, "annotation": "n_glycosylation_sequon" }, { "start_pos": 930, "end_pos": 932, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8JIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JIN4" }, { "id": "PF25204", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25204" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "DAAF9", "eco_id": "ECO_0000259", "start_pos": 748, "end_pos": 950, "start_aa": "Leu", "end_aa": "Trp", "glycosite_overlap": "" }, { "evidence": [ { "id": "B8JIN4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JIN4" }, { "id": "PF23319", "database": "Pfam", "url": 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The reference sequence was derived from JBMGRA010000013.1 and EH445496.1. On May 25, 2016 this sequence version replaced XP_009305705.1. Transcript Variant: This variant (1) represents the shortest transcript. Variants 1-3 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001314708", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314708" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JJ41", "url": "https://www.uniprot.org/uniprotkb/B8JJ41" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cimip5", "url": "https://www.uniprot.org/uniprotkb/B8JJ41", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-214", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-214", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000078140", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000078140", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "568411", "url": "https://www.ncbi.nlm.nih.gov/gene/568411", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020339", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020339", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:568411", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:568411", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DFFFMEG", "url": "https://omabrowser.org/oma/group/DFFFMEG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JJ41", "url": "https://www.orthodb.org/?gene=B8JJ41", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31909", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31909", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31909:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31909:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14945", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14945", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001314708", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314708", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JJ41", "url": "https://www.uniprot.org/uniprotkb/B8JJ41", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JJ41-1", "url": "https://www.uniprot.org/uniprotkb/B8JJ41-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-214", "url": "https://zfin.org/ZDB-GENE-090313-214", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDRKGNVRRATSAGYRLPDRPNGPLASQSSVSVFRHSAGRTRNGETPAQNEDSRDPVKQDQVWREFVRAERSGVKEWEKNWSFLMNFDQLGHPRTETPLPNSVSLYSDRLPNTSNQMFGSSLYTELGNELVRLDNLLILTSNHRKAKRNPEMQPC", "length": 155, "header": "tr|B8JJ41-1|B8JJ41_DANRE Isoform 1 of Uncharacterized protein C2orf50 homolog OS=Danio rerio OX=7955 GN=cimip5 PE=4 SV=1 CANONICAL=B8JJ41-1" }, "isoforms": [ { "isoform_ac": "B8JJ41-1", "url": "https://www.uniprot.org/uniprotkb/B8JJ41/entry#B8JJ41-1", "sequence": { "sequence": "MDRKGNVRRATSAGYRLPDRPNGPLASQSSVSVFRHSAGRTRNGETPAQNEDSRDPVKQDQVWREFVRAERSGVKEWEKNWSFLMNFDQLGHPRTETPLPNSVSLYSDRLPNTSNQMFGSSLYTELGNELVRLDNLLILTSNHRKAKRNPEMQPC", "length": 155, "header": "tr|B8JJ41-1|B8JJ41_DANRE Isoform 1 of Uncharacterized protein C2orf50 homolog OS=Danio rerio OX=7955 GN=cimip5 PE=4 SV=1 CANONICAL=B8JJ41-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. 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"https://alliancegenome.org/gene/HGNC:26324#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-214", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-214#orthology", "database": "AGR" }, { "id": "B8JJ41", "url": "https://omabrowser.org/oma/group/B8JJ41/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4A5F3-1", "protein_name": "Similar to human chromosome 2 open reading frame 50", "gene_name": "Cimip5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGSQHTGLPRTTSSGYQLPPTRQLATISPGRDGPAAGRALVGGSQGTLAPGVQQDQLWRELVEAEARGQRRWAENWGFLKDYDPLRVTWDVSSPQGNKKEPQELPANVPFFSDTFPSSTSREVGSRVDTPLGRALSHMDFFFVEGTRKKKPEDELQPV", "length": 158 }, "evidence": [ { "id": "RGD:1582838", "url": "https://alliancegenome.org/gene/RGD:1582838#orthology", "database": "AGR" }, { "id": "MGI:1920917", "url": "https://alliancegenome.org/gene/MGI:1920917#orthology", "database": "AGR" }, { "id": "HGNC:26324", "url": 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"field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JJQ4-1", "uniprot_ac": "B8JJQ4", "uniprot_id": "B8JJQ4_DANRE", "mass": { "chemical_mass": 57026.0, "monoisotopic_mass": 57026.0 }, "refseq": { "ac": "NP_001314981", "name": "peroxisomal N(1)-acetyl-spermine/spermidine oxidase", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314981" }, "gene_names": [ { "name": "paox", "type": "recommended", "evidence": [ { "id": "B8JJQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4" } ] }, { "name": "paox", "type": "synonym", "evidence": [ { "id": "NP_001314981", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314981" } ] }, { "name": "si:dkey-275b16.2", "type": "synonym", "evidence": [ { "id": "NP_001314981", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314981" }, { "id": "B8JJQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4" } ] } ], "protein_names": [ { "name": "1.5.3.13", "type": "synonym", "evidence": [ { "id": "B8JJQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4/entry#names_and_taxonomy" } ] }, { "name": "Peroxisomal N(1)-acetyl-spermine/spermidine oxidase", "type": "synonym", "evidence": [ { "id": "B8JJQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4/entry#names_and_taxonomy" } ] }, { "name": "peroxisomal N(1)-acetyl-spermine/spermidine oxidase", "type": "synonym", "evidence": [ { "id": "NP_001314981", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314981" } ] }, { "name": "polyamine oxidase (exo-N4-amino)", "type": "synonym", "evidence": [ { "id": "NP_001314981", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314981" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01008705.1, BC155664.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1 and BC155664.1. On Jun 3, 2016 this sequence version replaced XP_690593.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001314981", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314981" } ] } ], "disease": [ { "disease_id": "DOID:3908", "recommended_name": { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "lung non-small cell carcinoma", "description": "A lung carcinoma that is characterized as any type of epithelial lung cancer other than small cell lung carcinoma." }, "synonyms": [ { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "NSCLC", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "Non-small cell lung cancer", "description": "" }, { "id": "DOID:3908", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3908", "name": "non-small cell lung carcinoma", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3908", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3908" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JJQ4", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "paox", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090312-204", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-204", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000003380", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000003380", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "562105", "url": "https://www.ncbi.nlm.nih.gov/gene/562105", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR002937", "url": "https://www.ebi.ac.uk/interpro/entry/IPR002937", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036188", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036188", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050281", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050281", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562105", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562105", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GTHSMDE", "url": "https://omabrowser.org/oma/group/GTHSMDE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JJQ4", "url": "https://www.orthodb.org/?gene=B8JJQ4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10742", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10742", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10742:SF405", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10742:SF405", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF01593", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01593", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-141334", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-141334", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-351200", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-351200", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001314981", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314981", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JJQ4", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JJQ4-1", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090312-204", "url": "https://zfin.org/ZDB-GENE-090312-204", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDSMAQRPDRDSQIFIIGCGISGIGAAQKLIKHGFHNVRIIEATARSGGRIRTGRLGDNIIEIGANWIHGPSKENPVFRLACDYQLLDKESMSEENQAIDIGGHPLFVPNWFTSSGRKLGPETMGPALEFFMTLLERSQQFHSTGGEPLPSVGEFIKAEAERLAPEEWKEDRDNFAVRMAMINTLLKLECCVSGTHTMDDVGLGAFGMYTTLPGLDCTFPGGYEGLTDHMMKELPRDIVLYNKPVKCIHWNYTKNGPNTGGTSFPVTIECVNGETFAADHVIVTVPLGYMKKHQNTFLSPSFPLHKLHSIQRMGFGTNNKIFVEFEQPFWDEDCELIYLVWEDETHLTDVVSDLKMSWIRKLTGFTVLKPTERFGHVLCGWIAGQESEYMESLSELEVLQTVTQLLRIFTGNPTIMPRKLLRSQWFHEPYSCGSYSYVAKGCSGYDIDNLAEPLPLKGSNSKPLQVLFAGEATHRSFFSTVHGALLSGWREAERLISHHTSASGSFSSKL", "length": 510, "header": "tr|B8JJQ4-1|B8JJQ4_DANRE Isoform 1 of Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Danio rerio OX=7955 GN=paox PE=3 SV=1 CANONICAL=B8JJQ4-1" }, "isoforms": [ { "isoform_ac": "B8JJQ4-1", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4/entry#B8JJQ4-1", "sequence": { "sequence": "MDSMAQRPDRDSQIFIIGCGISGIGAAQKLIKHGFHNVRIIEATARSGGRIRTGRLGDNIIEIGANWIHGPSKENPVFRLACDYQLLDKESMSEENQAIDIGGHPLFVPNWFTSSGRKLGPETMGPALEFFMTLLERSQQFHSTGGEPLPSVGEFIKAEAERLAPEEWKEDRDNFAVRMAMINTLLKLECCVSGTHTMDDVGLGAFGMYTTLPGLDCTFPGGYEGLTDHMMKELPRDIVLYNKPVKCIHWNYTKNGPNTGGTSFPVTIECVNGETFAADHVIVTVPLGYMKKHQNTFLSPSFPLHKLHSIQRMGFGTNNKIFVEFEQPFWDEDCELIYLVWEDETHLTDVVSDLKMSWIRKLTGFTVLKPTERFGHVLCGWIAGQESEYMESLSELEVLQTVTQLLRIFTGNPTIMPRKLLRSQWFHEPYSCGSYSYVAKGCSGYDIDNLAEPLPLKGSNSKPLQVLFAGEATHRSFFSTVHGALLSGWREAERLISHHTSASGSFSSKL", "length": 510, "header": "tr|B8JJQ4-1|B8JJQ4_DANRE Isoform 1 of Peroxisomal N(1)-acetyl-spermine/spermidine oxidase OS=Danio rerio OX=7955 GN=paox PE=3 SV=1 CANONICAL=B8JJQ4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JJQ4", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "B8JJQ4", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] }, { "title": "Insights Into the Peroxisomal Protein Inventory of Zebrafish.", "journal": "Front. Physiol.", "date": "2022", "authors": "Kamoshita Maki, Kumar Rechal, Anteghini Marco, Kunze Markus, Islinger Markus, Martins Dos Santos V\u00edtor, Schrader Michael", "evidence": [ { "database": "UniProtKB", "id": "B8JJQ4", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4" } ], "reference": [ { "type": "PubMed", "id": "35295584", "url": "https://glygen.org/publication/PubMed/35295584" } ] } ], "pathway": [ { "id": "dre:562105", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562105", "resource": "KEGG Pathway" }, { "id": "R-DRE-141334", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-141334", "resource": "Reactome", "description": "PAOs oxidise polyamines to amines" }, { "id": "R-DRE-351200", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-351200", "resource": "Reactome", "description": "Interconversion of polyamines" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4LET0-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "Dmel\\CG7737", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLYGKWTVIKLKCLELQCTIAISKFPMHNIQLPGMSGAQRNQDRKIVVIGAGASGVACATKLLELGFQNVLVVEAEDRLGGRIHTIPFADNVIDLGAQWCHGERDNIVYELTRKQDEELLESTGPVYENYECVRSNGDVVPEEVSSRLKAIVGDSLVTRQLELRHCSGSLGSYLTNKFYDTLRRPENSDIDAEVASEFFVNYQKFENSVEASDTLEQVSGRGYLDYWECEGDILLNWKDKGYVELLRLLMRSRELNVEHGVLEQRLLLGTRVVKINWNRNDGRVELQMSNGETCIADHVVVTVSLGVLKDQHLRLFEPQLPVEKQRAIDGLAFGTVNKIFVEFPEAFWPEDWTGFTMLWRDEDLDDIRGTSRAWLEDVFGFYRVSYQPRILAGWITNESGRHMETLPVDEVQAGVMYLFRRFLRWKIPDPANFRTSAWYTNDNFRGSYSYRSMDTEQLGTGARELSHPLTVVATTPEKDKDSEDEAWQQSRCDRPIVQFAGEASSEHYYSTVHGAVEAGWREARRLAQFYGISVSRSGTKSQL", "length": 543 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090312-204", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-204#orthology", "database": "AGR" }, { "id": "FB:FBgn0033584", "url": "https://alliancegenome.org/gene/FB:FBgn0033584#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8I6AEP5-1", "protein_name": "Polyamine oxidase", "gene_name": "Paox", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTYHLSPSASHKPRLRPTQPHAHSLVPFYTTPPSSPPLAPPRPPLLRRPTATGQKYSELAMAARGPRVLVVGGGIAGLGAVQRLCHHRAAPHLRVLEATACAGGRIRSERCFGGVVELGAHWIHGPSQGNPVFQLAAEFGLLGEKELSEENQLVETGGHVALPSVSCTSSGTSVSLELVTEMGSLFYGLIDRTREFLNESETPMASVGEFLKKEISQQVANWTEDENTKRLKLAVLNTFFNIECCVSGTHSMDLVALAPFGEYTVLPGLDCTLSGGYQGLTNCILASLPKEVMVFDKPVKTIHWNGSFQEAAFPGETFPVLVECEDGARLPAHHVIVTVPLGFLKEHQDTFFEPPLPAKKAEAIRKLGFGTNNKIFLEFEEPFWEPDCQFIQVVWEDTSPLQDSPLSLQDTWFKKLIGFLVLPSFESSHVLCAFIAGLQSEFMETLSDEEVLLSLTQVLRRVTGNPQLPAAKSVLRSRWHSAPYTRGSYSYVAVGSTGDDLDLMAQPLPADGTGTQLQVLFAGEATHRTFYSTTHGALLSGWREADRLIGLWDSQAEQSRPRL", "length": 564 }, "evidence": [ { "id": "MGI:1916983", "url": "https://alliancegenome.org/gene/MGI:1916983#orthology", "database": "AGR" }, { "id": "HGNC:20837", "url": "https://alliancegenome.org/gene/HGNC:20837#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-204", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-204#orthology", "database": "AGR" }, { "id": "FB:FBgn0037606", "url": "https://alliancegenome.org/gene/FB:FBgn0037606#orthology", "database": "AGR" }, { "id": "RGD:1561125", "url": "https://alliancegenome.org/gene/RGD:1561125#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6G2K8-1", "protein_name": "Lysine-specific histone demethylase 1A", "gene_name": "Kdm1a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSGKKAAAAAAAAAAAAAGTEAGPGAAGGAENGSEVAAPPAGLAGPADIATGAAGERTPRKKEPPRASPPGGLAEPPGSAGPQAGPTAGPGSATPMETGIAETPEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPIKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQATPGVPAQQSPSM", "length": 852 }, "evidence": [ { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1NH10-1", "protein_name": "Amine oxidase", "gene_name": "paox1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MVDRSPSIVVVGAGVAGLAAAKKLKEYGFNDVTVLEAAENVGGRVATATLGNACVDTGAQYIHGTSEKNPVYCLLKGLLNQLPEMGEEAFYNNKGHKVNANFARRAYEHGESFIYHRGSGNSGKSLGEHYAVKTQGVIERLQEDEKARMQSVFALVGKDMLIDIGASDLHRISLDSWQYYIDMGDSVNITGFMYQLVDLLKEDFPKDRLLLKREVRTIKWDGSFPSPQNEASPEGKVRQYPVCIVCEDGEEILADHVIVTVSLGCLKAQASDLFIPSLPTEKIEVINKLCFGNIAKIFLAYEEAFWENDVGSISFIYEDDTPASISTNKMQWLKSMQSFSVLRPKERFGNVLIGWCPGEIADLVETMTDNELSAAVTDHLKMFFGPSANIPQPKSILCTKWRSNKFIKGSYTFLPVGVDGQVMDTLAQPLEGSQFPDAHLQVMFAGEATMKTLYGTVQGALLSGHREADRLAAHYKDAVASTSASMDKHV", "length": 490 }, "evidence": [ { "id": "FB:FBgn0033584", "url": "https://alliancegenome.org/gene/FB:FBgn0033584#orthology", "database": "AGR" }, { "id": "FB:FBgn0002036", "url": "https://alliancegenome.org/gene/FB:FBgn0002036#orthology", "database": "AGR" }, { "id": "FB:FBgn0036749", "url": "https://alliancegenome.org/gene/FB:FBgn0036749#orthology", "database": "AGR" }, { "id": "FB:FBgn0036750", "url": "https://alliancegenome.org/gene/FB:FBgn0036750#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8M2BG04-1", "protein_name": "Uncharacterized protein isoform X1", "gene_name": "fi17d03", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNYKGQVLQVLQVLSYIKATLKWLNKAATMSTGPENAKVLVIGSGFAGLAAASKLIEAGFEDVLVLEAKERVGGRVHTTKPFTENIIEVGANWIHGQKGNPLYKIAKEKNLLSEGPSAMKNMCLPHSVSPRDYFFNEDGKPVPKSVVDQVCARFSKLTDKAFDDELDGKYRKLTLGAYLDDAFGGTELSKTEDARQVYEWCKRVECTDEACSSLYEISASQLSNYTELEGGFFNTLGPGGYQAILDVLLRDVPSEAVRCNAPVKTIRWDLVKEGQSEEEDHPVQVVCENGQTFEADHVIVTVSLGVLKEHAKTMFDPTLPEKKLSAINDLGFGIVNKIFLFFEKSFWPDDCAGVQLVWKEGPEDKDVYEDLSEGEDWKQTWFKKITGFDTVARHPTALCGWITGREALYMESLQDREIQEVCVRLLRSSTGWPVPEVSKTLISRWGSDPQVRGSYTFVPDGVDGVEAHKALASPLPPKHRSRGRKNLQVLFAGEATHVNFYTTTHGAYLSGQREAERLISYYSD", "length": 524 }, "evidence": [ { "id": "FB:FBgn0037606", "url": "https://alliancegenome.org/gene/FB:FBgn0037606#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8V0ZQU7-1", "protein_name": "Peroxisomal N(1)-acetyl-spermine/spermidine oxidase", "gene_name": "PAOX", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MERGGGGRRVLVVGAGMAALGAAQRLRGPGSVRLLEAGGRVGGRVCSLPFASGLAELGAHWIHGPSEGNPVFRLASSYGLLGPGATEEENQRVEAKGHPLLPVVTYGSSGKVLSPELVNGTRSLFSELLGSAQALVGAEEPPATSVGQYMRAEIARLASGWDEDKDDKRLRLAILSACLKLECCISGTHSMDMVALGSFGEYTSLPGLDCTFPCGYSSLPERILETLPEGTVLLNKPVRTIRWQGSFREEGDTDRDFPVQVECEDGDSFLTDHVIVTVPLGFLKERHQDFFQPPLPERKAEAIRRLGFGTNNKIFLEFEQPFWEPEQQLLEIVWEDESPLAEPSADLEANWFKKLIGFVVLQPPEQLGHVLCGFIAGKESEYMETLSDAEVLSTMTNVLRTLTGNPHLPTPRSVLRSCWHSAPYTRGSYSYVAVGSSGEDIDTLAQPLPEDASDPRVRAWRVIVWDLGRLQGKMGGAVACAQGAQSSVQGHLGPVVWNGETGWENTSSLKLGRCGLQDASQNPLGMGHFPKASGTHSISRYT", "length": 542 }, "evidence": [ { "id": "B8JJQ4", "url": "https://omabrowser.org/oma/group/B8JJQ4/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "D3ZP89-1", "protein_name": "[histone-H3]-N(6),N(6)-dimethyl-L-lysine(4) FAD-dependent demethylase", "gene_name": "Kdm1b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASRGRSKKRSNFELSPDTLPLRSSGRQAKKKAVEITEEDEDGSSEKKYRKCEKAGCTTAYPVCFASASERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYTAWKRVWTSNGKTEPSPKAFMADQQLPYWVQCTKPECRKWRQLTKEIQLTPHMARTYRCGMKPNTITKPDTPDHCSFPEDLRVLEVSNHWWYSMLIQPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTHRAAVTATATGSASPGEMEPSKAAPASLVLGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEALTPQKCIPHVIVRGLVRIRCVQEVERILYFMTRKGLINTGVLTVGAGQHLLPKHYHNKSVLVVGAGPAGLAAARQLHNFGMKVTVLEAKDRIGGRVWDDKSFKGVVVGRGPQIVNGCINNPVALMCEQLGIRMHKLGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTLLQDVPLGEKIEEIYRAFVKESGIQFSELEGQVLQFHLSNLEYACGSSLHQVSARSWDHNEFFAQFAGDHTLLTPGYSTIVEKLAEGLDIRLKSPVQSIDYTGDEVQVTTTDGVVHSAQKVLVTVPLAMLQRGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASQRGLFAVFYDMGPQQQSVLMSVITGEAVASLRTMDDKQVLQQCLGVLRELFKEQEIPDPTKYFVTRWNTEPWIQMAYSFVKTFGSGEAYDIIAEEIQGTVYFAGEATNRHFPQTVTGAYLSGVREASKIAAF", "length": 825 }, "evidence": [ { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O60341-1", "protein_name": "Lysine-specific histone demethylase 1A", "gene_name": "KDM1A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSGKKAAAAAAAAAAAATGTEAGPGTAGGSENGSEVAAQPAGLSGPAEVGPGAVGERTPRKKEPPRASPPGGLAEPPGSAGPQAGPTVVPGSATPMETGIAETPEGRRTSRRKRAKVEYREMDESLANLSEDEYYSEEERNAKAEKEKKLPPPPPQAPPEEENESEPEEPSGVEGAAFQSRLPHDRMTSQEAACFPDIISGPQQTQKVFLFIRNRTLQLWLDNPKIQLTFEATLQQLEAPYNSDTVLVHRVHSYLERHGLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQLDFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNLKEKIKELHQQYKEASEVKPPRDITAEFLVKSKHRDLTALCKEYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILDWHFANLEFANATPLSTLSLKHWDQDDDFEFTGSHLTVRNGYSCVPVALAEGLDIKLNTAVRQVRYTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQFLGAMYTLPRQATPGVPAQQSPSM", "length": 852 }, "evidence": [ { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P18487-1", "protein_name": "Protein anon-37Cs", "gene_name": "anon-37Cs", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQCFKLASRRSLYNARVLQADNIGDKQRSPDLEAARQNTQIVVVGAGLAGLSAAQHLLSHGFRRTVILEATDRYGGRINTQRFGDTYCELGAKWVKIDGSQDSMYELLRNTEGLGKQIKQPDRATYLQDGSRINPAMVELIDTLFRQLCRGFKVSERVKTGGDLHSLDNVMNYFRTESDRIIGVSFQHPKDQLAAREIFQSLFKEFGSILGCCLEYVNIEHITKCPVQQEQRPLYVPTGLDNVVDDLIQNMDKAQLQTGKPVGQIQWTPAPMKSVGCLDGSLYNADHIICTLPLGVLKSFAGVLFRPTLPLDKMLAIRNLGFGNPLKIYLSYKKPIGRWLKGSLRPLGTLLNPSVEQQPERNWTQQVVEISQVPSSQHVLEVHVGGGYYEEIEKLPDEELLEQITGLLRRCVSSHLVPYPQELLRSNWSTSACYLGGRPYFSTNSSARDVQRLAAPLGEKSPGLLFAGDATSLRGFGTIDAARSSGIREAQRIIDYYLKSVHCG", "length": 504 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090312-204", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-204#orthology", "database": "AGR" }, { "id": "FB:FBgn0002036", "url": "https://alliancegenome.org/gene/FB:FBgn0002036#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "P21397-1", "protein_name": "Amine oxidase [flavin-containing] A", "gene_name": "MAOA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MENQEKASIAGHMFDVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQNRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNMGKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWFLWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNIIIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAFWKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKICELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAGTETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERNLPSVSGLLKIIGFSTSVTALGFVLYKYKLLPRS", "length": 527 }, "evidence": [ { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P50264-1", "protein_name": "Polyamine oxidase FMS1", "gene_name": "FMS1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MNTVSPAKKKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDIGASWHHDTLTNPLFLEEAQLSLNDGRTRFVFDDDNFIYIDEERGRVDHDKELLLEIVDNEMSKFAELEFHQHLGVSDCSFFQLVMKYLLQRRQFLTNDQIRYLPQLCRYLELWHGLDWKLLSAKDTYFGHQGRNAFALNYDSVVQRIAQSFPQNWLKLSCEVKSITREPSKNVTVNCEDGTVYNADYVIITVPQSVLNLSVQPEKNLRGRIEFQPPLKPVIQDAFDKIHFGALGKVIFEFEECCWSNESSKIVTLANSTNEFVEIVRNAENLDELDSMLEREDSQKHTSVTCWSQPLFFVNLSKSTGVASFMMLMQAPLTNHIESIREDKERLFSFFQPVLNKIMKCLDSEDVIDGMRPIENIANANKPVLRNIIVSNWTRDPYSRGAYSACFPGDDPVDMVVAMSNGQDSRIRFAGEHTIMDGAGCAYGAWESGRREATRISDLLK", "length": 508 }, "evidence": [ { "id": "MGI:1916983", "url": "https://alliancegenome.org/gene/MGI:1916983#orthology", "database": "AGR" }, { "id": "HGNC:20837", "url": "https://alliancegenome.org/gene/HGNC:20837#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-204", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-204#orthology", "database": "AGR" }, { "id": "FB:FBgn0033584", "url": "https://alliancegenome.org/gene/FB:FBgn0033584#orthology", "database": "AGR" }, { "id": "FB:FBgn0002036", "url": "https://alliancegenome.org/gene/FB:FBgn0002036#orthology", "database": "AGR" }, { "id": "FB:FBgn0036749", "url": "https://alliancegenome.org/gene/FB:FBgn0036749#orthology", "database": "AGR" }, { "id": "FB:FBgn0037606", "url": "https://alliancegenome.org/gene/FB:FBgn0037606#orthology", "database": "AGR" }, { "id": "FB:FBgn0036750", "url": "https://alliancegenome.org/gene/FB:FBgn0036750#orthology", "database": "AGR" }, { "id": "RGD:1561125", "url": "https://alliancegenome.org/gene/RGD:1561125#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6QHF9-2", "protein_name": "Peroxisomal N(1)-acetyl-spermine/spermidine oxidase", "gene_name": "PAOX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MESTGSVGEAPGGPRVLVVGGGIAGLGAAQRLCGHSAFPHLRVLEATARAGGRIRSERCFGGVVEVGAHWIHGPSRGNPVFQLAAEYGLLGEKELSQENQLVETGGHVGLPSVSYASSGASVSLQLVAEMATLFYGLIDQTREFLHAAETPVPSVGEYLKKEIGQHVAGWTEDEETRKLKLAVLNSFFNLECCVSGTHSMDLVALAPFGEYTVLPGLDCTFSKGYQGLTNCMMAALPEDTVVFEKPVKTIHWNGSFQEAAFPGETFPVSVECEDGDRFPAHHVIVTVPLGFLREHLDTFFDPPLPAEKAEAIRKIGFGTNNKIFLEFEEPFWEPDCQLIQLVWEDTSPLEDAAPELQDAWFRKLIGFVVLPAFASVHVLCGFIAGLESEFMETLSDEEVLLCLTQVLRRVTGNPRLPAPKSVLRSRWHSAPYTRGSYSYVAVGSTGGDLDLLAQPLPADGAGAQLQILFAGEATHRTFYSTTHGALLSGWREADRLLSLWAPQVQQPRPRL", "length": 511 }, "evidence": [ { "id": "MGI:1916983", "url": "https://alliancegenome.org/gene/MGI:1916983#orthology", "database": "AGR" }, { "id": "HGNC:20837", "url": "https://alliancegenome.org/gene/HGNC:20837#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-204", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-204#orthology", "database": "AGR" }, { "id": "FB:FBgn0037606", "url": "https://alliancegenome.org/gene/FB:FBgn0037606#orthology", "database": "AGR" }, { "id": "RGD:1561125", "url": "https://alliancegenome.org/gene/RGD:1561125#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8C0L6-1", "protein_name": "Peroxisomal N(1)-acetyl-spermine/spermidine oxidase", "gene_name": "Paox", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAFPGPRVLVVGSGIAGLGAAQKLCSHRAAPHLRVLEATASAGGRIRSERCFGGVVELGAHWIHGPSQDNPVFQLAAEFGLLGEKELSEENQLVDTGGHVALPSMIWSSSGTSVSLELMTEMARLFYGLIERTREFLNESETPMASVGEFLKKEISQQVASWTEDDEDTRKRKLAILNTFFNIECCVSGTHSMDLVALAPFGEYTVLPGLDCILAGGYQGLTDRILASLPKDTVAFDKPVKTIHWNGSFQEAAFPGETFPVLVECEDGARLPAHHVIVTVPLGFLKEHQDTFFEPPLPAKKAEAIKKLGFGTNNKIFLEFEEPFWEPDCQFIQVVWEDTSPLQDTALSLQDTWFKKLIGFLVQPSFESSHVLCGFIAGLESEFMETLSDEEVLLSLTQVLRRVTGNPQLPAAKSVRRSQWHSAPYTRGSYSYVAVGSTGDDLDLMAQPLPEDGTGTQLQVLFAGEATHRTFYSTTHGALLSGWREADRLVSLWDSQVEQSRPRL", "length": 504 }, "evidence": [ { "id": "MGI:1916983", "url": "https://alliancegenome.org/gene/MGI:1916983#orthology", "database": "AGR" }, { "id": "HGNC:20837", "url": "https://alliancegenome.org/gene/HGNC:20837#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-204", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-204#orthology", "database": "AGR" }, { "id": "FB:FBgn0037606", "url": "https://alliancegenome.org/gene/FB:FBgn0037606#orthology", "database": "AGR" }, { "id": "RGD:1561125", "url": "https://alliancegenome.org/gene/RGD:1561125#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8CIG3-1", "protein_name": "Lysine-specific histone demethylase 1B", "gene_name": "Kdm1b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASRGRSKKRSNLELSPDNLPLRSSGRQAKKKAVEIPDEDEDGSSEKKYRKCEKAGCTAAYPVCFASASERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYSAWKRVWTSNGKTEPSPKAFMADQQLPYWVQCTKPECGKWRQLTKEIQLTPHMARTYRCGMKPNTITKPDTPDHCSFPEDLRVLEVSNHWWYPMLIQPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTHRATVTAATTTTGSASPGEMEPSKAAPSSLVLGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLTVAAGQHLLPKHYHNKSVLVVGAGPAGLAAARQLHNFGMKVTVLEAKDRIGGRVWDDKSFKGVVVGRGPQIVNGCINNPVALMCEQLGISMRKLGERCDLIQEGGRITDPTVDKRMDFHFNALLDVVSEWRKDKTLLQDVPLGEKIEEIYRAFVKESGIQFSELEGQVLQFHLSNLEYACGSSLHQVSARSWDHNEFFAQFAGDHTLLTPGYSTIIEKLAEGLDIRLKSPVQSIDYTGDEVQVTTTDGMGHSAQKVLVTVPLAILQRGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASQRGLFAVFYDMDSQQSVLMSVITGEAVASLRTMDDKQVLQQCMGILRELFKEQEIPEPTKYFVTRWSTEPWIQMAYSFVKTFGSGEAYDIIAEEIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF", "length": 826 }, "evidence": [ { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NB78-1", "protein_name": "Lysine-specific histone demethylase 2", "gene_name": "KDM1B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATPRGRTKKKASFDHSPDSLPLRSSGRQAKKKATETTDEDEDGGSEKKYRKCEKAGCTATCPVCFASASERCAKNGYTSRWYHLSCGEHFCNECFDHYYRSHKDGYDKYTTWKKIWTSNGKTEPSPKAFMADQQLPYWVQCTKPECRKWRQLTKEIQLTPQIAKTYRCGMKPNTAIKPETSDHCSLPEDLRVLEVSNHWWYSMLILPPLLKDSVAAPLLSAYYPDCVGMSPSCTSTNRAAATGNASPGKLEHSKAALSVHVPGMNRYFQPFYQPNECGKALCVRPDVMELDELYEFPEYSRDPTMYLALRNLILALWYTNCKEALTPQKCIPHIIVRGLVRIRCVQEVERILYFMTRKGLINTGVLSVGADQYLLPKDYHNKSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCINNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFHFNALLDVVSEWRKDKTQLQDVPLGEKIEEIYKAFIKESGIQFSELEGQVLQFHLSNLEYACGSNLHQVSARSWDHNEFFAQFAGDHTLLTPGYSVIIEKLAEGLDIQLKSPVQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAGIIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEAVASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGEAYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKIAAF", "length": 822 }, "evidence": [ { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q99K82-1", "protein_name": "Spermine oxidase", "gene_name": "Smox", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAARALLEQGFTDVTVLEASSHIGGRVQSVRLGDTTFELGATWIHGSHGNPIYQLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNRGCRIPKDVVEEFSDLYNEVYNMTQEFFRHGKPVNAESQNSVGVFTREKVRNRIRDDPDDTEATKRLKLAMIQQYLKVESCESSSHSIDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPPHVIQLGKPVRCIHWDQASAHPRGPEIEPRGEGDHNHDTGEGGQSGENPQQGRWDEDEPWPVVVECEDCEVIPADHVIVTVSLGVLKRQYTSFFRPCLPTEKVAAIHRLGIGTTDKIFLEFEEPFWGPECNSLQFVWEDEAESCTLTYPPELWYRKICGFDVLYPPERYGHVLSGWICGEEALVMERCDDEAVAEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQGP", "length": 555 }, "evidence": [ { "id": "FB:FBgn0033584", "url": "https://alliancegenome.org/gene/FB:FBgn0033584#orthology", "database": "AGR" }, { "id": "FB:FBgn0002036", "url": "https://alliancegenome.org/gene/FB:FBgn0002036#orthology", "database": "AGR" }, { "id": "FB:FBgn0036749", "url": "https://alliancegenome.org/gene/FB:FBgn0036749#orthology", "database": "AGR" }, { "id": "FB:FBgn0037606", "url": "https://alliancegenome.org/gene/FB:FBgn0037606#orthology", "database": "AGR" }, { "id": "FB:FBgn0036750", "url": "https://alliancegenome.org/gene/FB:FBgn0036750#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9NWM0-1", "protein_name": "Spermine oxidase", "gene_name": "SMOX", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQSCESSGDSADDPLSRGLRRRGQPRVVVIGAGLAGLAAAKALLEQGFTDVTVLEASSHIGGRVQSVKLGHATFELGATWIHGSHGNPIYHLAEANGLLEETTDGERSVGRISLYSKNGVACYLTNHGRRIPKDVVEEFSDLYNEVYNLTQEFFRHDKPVNAESQNSVGVFTREEVRNRIRNDPDDPEATKRLKLAMIQQYLKVESCESSSHSMDEVSLSAFGEWTEIPGAHHIIPSGFMRVVELLAEGIPAHVIQLGKPVRCIHWDQASARPRGPEIEPRGEGDHNHDTGEGGQGGEEPRGGRWDEDEQWSVVVECEDCELIPADHVIVTVSLGVLKRQYTSFFRPGLPTEKVAAIHRLGIGTTDKIFLEFEEPFWGPECNSLQFVWEDEAESHTLTYPPELWYRKICGFDVLYPPERYGHVLSGWICGEEALVMEKCDDEAVAEICTEMLRQFTGNPNIPKPRRILRSAWGSNPYFRGSYSYTQVGSSGADVEKLAKPLPYTESSKTAPMQVLFSGEATHRKYYSTTHGALLSGQREAARLIEMYRDLFQQGT", "length": 555 }, "evidence": [ { "id": "FB:FBgn0033584", "url": "https://alliancegenome.org/gene/FB:FBgn0033584#orthology", "database": "AGR" }, { "id": "FB:FBgn0002036", "url": "https://alliancegenome.org/gene/FB:FBgn0002036#orthology", "database": "AGR" }, { "id": "FB:FBgn0036749", "url": "https://alliancegenome.org/gene/FB:FBgn0036749#orthology", "database": "AGR" }, { "id": "FB:FBgn0037606", "url": "https://alliancegenome.org/gene/FB:FBgn0037606#orthology", "database": "AGR" }, { "id": "FB:FBgn0036750", "url": "https://alliancegenome.org/gene/FB:FBgn0036750#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9SU79-1", "protein_name": "Probable polyamine oxidase 5", "gene_name": "PAO5", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MAKKARIVIIGAGMAGLTAANKLYTSSNNTFELSVVEGGSRIGGRINTSEFSSEKIEMGATWIHGIGGSPVYRIAKETGSLVSDEPWECMDSTIDKAKTFAEGGFEIEPSIVESISGLFTALMELAQGKEISQSDADLSRLAHIYETATRVCSKGSSTSVGSFLKSGFDAYWDSISNGGEEGVKGYGKWSRKSLEEAIFTMFSNTQRTYTSADELSTLDFAAESEYQMFPGEEITIAKGYLSVIHHLASVLPQGVIQLNRKVTKIEWQSNEVKLHFSDGSVVFADHVIVTVSLGVLKAGIETDAELFSPPLPDFKSDAIRRLGYGVVNKLFVEMSQRKFPSLQLVFDREDSEFRFVKIPWWMRRTATITPIHSNSKVLLSWFAGKEALELEKLTDEEIKDAVMTTISCLTGKEVKNDTAKPLTNGSLNDDDEAMKITKVLKSKWGSDPLFRGSYSYVAVGSSGDDLDAMAEPLPKINKKVGQVNGHDQAKVHELQVMFAGEATHRTHYSTTHGAYYSGLREANRLLKHYKCNF", "length": 533 }, "evidence": [ { "id": "B8JJQ4", "url": "https://omabrowser.org/oma/group/B8JJQ4/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q9VHN8-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "Dmel\\CG8032", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MGDKEEPVTPAPSPTEEGMANIGSAGAGDQPQTSGNNTNVKIVIIGAGMAGLSAANHLLQNGCDDFLILEARGRVGGRIVSIPLSNNQKIELGANWIHGVLGNPIFELAVQHGLVSVVNVPKPHKVVATTEDGHQVPFNILQEIYEAYVCFLRRCDEYFLCQYSPPPDIHSVGEHINYEIEIYLSGVQDPKEKRLKQSIFNCLLKRETCITGCNNMDEVDLLELGSYTELQGGNIVLPTGYSSILRPLGAQIAKQSILTKCPVKKIHWKRKKTFTGLETVDENSEDEHSDDSERTVTEVPTGEIRGASVESNTSSNCDYPAGNVRIDCEDGRVFHAAHVICTIPLGVLKNTHRTLFDPVLPQYKQESIENLMFGTVDKIFLEYERPFLSADISEIMLLWDDDKRDMNSSEEELASEAYLSKNWFKKIYSFAKVTDTLLLGWVSGREAEYMEKLDHEAVAEKCTEILRNFLQDPYVPKPKRCVCTSWKSQDFTGGAYTSIPVGATQEDIENLAQPLYATPQAMKPAIVFAGEHTHSSFYSTVHGAYLSGRTAAQHLLASDEPDEIIMESDGSDLSAWIQGIALD", "length": 583 }, "evidence": [ { "id": "MGI:1916983", "url": "https://alliancegenome.org/gene/MGI:1916983#orthology", "database": "AGR" }, { "id": "HGNC:20837", "url": "https://alliancegenome.org/gene/HGNC:20837#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-204", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-204#orthology", "database": "AGR" }, { "id": "FB:FBgn0037606", "url": "https://alliancegenome.org/gene/FB:FBgn0037606#orthology", "database": "AGR" }, { "id": "RGD:1561125", "url": "https://alliancegenome.org/gene/RGD:1561125#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VSR8-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "Dmel\\CG5653", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEKCRASSRIIIIGAGVSGIAAATRLLQNNFQNVQILEAEDRIGGRINTVYFGDNVIDLGAQWCHGKQQNCVYDMVKDMGILHETGDYYSPIKRVRSNKEVVPHELACRIHDIAVKSMPSGPHPVVGSFGTHLTQTFWRKIESELPQVNRDVASEALNTFAKHESSIIGADNLFEVSVREHIEYHECDGDKLLHWGTKGYRRFLRLLMKVSADTPEELGLLEGRIQLDMKVIKIELACPRKVILRCQDGDYFEADHVICTVSLGVLQEQHEKLFVPPLPAAKVNAIRSLTLGTVNKLYLEYEKQPLPDGWVGFFCFWLEEDLIELRKTEYFWVEGITGVHMITCQPRMLMAWVNGPHGRHMETLSDEKVLEGLYWLFRKFLTFEIPPPKRFVRSSWFSNPNFRGSWSYRGVMADERNTGPWDLESPVLGEDGHLGLLFAGEASSRNHFSTVHGAVEAGYREADRLIDHYTSCSVSA", "length": 476 }, "evidence": [ { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVK1-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "Dmel\\CG7460", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSSASLRLLSKTRQTARIVIVGAGSAGIAAATRLLDLGFRNVLLLEAEDRIGGRVHTIPFADNVVDLGAQWCHGEKGNVVYDKVKDLNLLEVTEPHYETFRCVRSNKEVLPDDLADQLKTIADMSIPDRQAELLDFEGSLGDYINMKYWKELAKLPPIDRTIAEEFLEVFHKFEASVEAADHLFEVSGKGHLEYWLCEGELLLNWKDKGYKRFLKLLMKAPEDQSEDLGILKDHVRLNRRIAEINWKGADELTVRCWNGEVITADHVICTVSLGVLKEQHPKLFVPALPAAKVRAIEGLKLGTVDKFFLEFENPPLPGDWPGFNCLWLKEDLEELRASELFWLESVFGFYPVSRQPRILQGWIIGPHARHMETLTEERVLEGLLWLFRKFLPFETAHPVRMLRTQWHANPNFRGSYTFRSTYTDALRTGAWDLEAPLQDVCGRPRLQFAGESTHKHFYSTVHGAVETGWREAERLHLYYRARTSQL", "length": 486 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090312-204", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-204#orthology", "database": "AGR" }, { "id": "FB:FBgn0036749", "url": "https://alliancegenome.org/gene/FB:FBgn0036749#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VVK2-1", "protein_name": "Amine oxidase domain-containing protein", "gene_name": "Dmel\\CG6034", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSACSEPTTFSKTKETAKIVIIGAGASGVAAATKLLEQGFKNVLLFEAEDRIGGRINTILFANSLIDLGAQWCHGEEGNVVYEKVKDLDVLDRTGDYVVHFIRSNKEILTDVHNKALTELTNAFEVPGEHEGSVGDAFNAYWKENIHQLVPNDKTIAKEAQDCLKKVICSMDACDNLSELSYRNFRNFAIAGGDQNLSWRQKGYWKFLSVLLNSSDNQPGDQGILKGHVHLNKRIAKINWEGDGELTLRCWNGQFVSADHVICTVSLGVLREKHHKLFVPALPASKIRSIEGLKLGTVNKFYLEFEEQPVPENIREMAFLWLEEDLKELRSGKYFWLESVCYFHRVDCQPRLLQGWIIGAHSRYVETISEEQVLEGIMWMFRKFLKFSVPYPKNFLRSQWQSNPNFRGSYSYYSTYADELRTGRTDLASPLVDVTGRPRIQFAGEASSRNHFSTVHGAIESGWREAERLNEFYEGRAAN", "length": 479 }, "evidence": [ { "id": "ZFIN:ZDB-GENE-090312-204", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-204#orthology", "database": "AGR" }, { "id": "FB:FBgn0036750", "url": "https://alliancegenome.org/gene/FB:FBgn0036750#orthology", "database": "AGR" }, { "id": "SGD:S000004622", "url": "https://alliancegenome.org/gene/SGD:S000004622#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "spermidine catabolic process", "id": "GO:0046203", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046203", "evidence": [ { "database": "UniProtKB", "id": "B8JJQ4", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B8JJQ4", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "polyamine oxidase activity", "id": "GO:0046592", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046592", "evidence": [ { "database": "UniProtKB", "id": "B8JJQ4", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4" } ], "pmid": "" }, { "name": "N(1)-acetylpolyamine oxidase (3-acetamidopropanal-forming) activity", "id": "GO:0052903", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0052903", "evidence": [ { "database": "UniProtKB", "id": "B8JJQ4", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 251, "end_pos": 253, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DRE-141348", "name": "PAO:FAD oxidises NASPM to PTCN", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-141349" ], "output_participant_list": [ "R-ALL-141327", "R-ALL-141350" ], "enzyme_list": [ "B8JJQ4-1" ], "evidence": [ { "id": "R-DRE-141348", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-141348" } ] }, { "id": "R-DRE-141351", "name": "PAOX:FAD oxidises NASPN to SPM", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "peroxisomal matrix", "input_participant_list": [ "R-ALL-141323" ], "output_participant_list": [], "enzyme_list": [ "B8JJQ4-1" ], "evidence": [ { "id": "R-DRE-141351", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-141351" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-141323", "participant_name": "NASPN [peroxisomal matrix]", "crossref": [ { "id": "58101", "database": "ChEBI", "url": "" }, { "id": "ZINC000003870097", "database": "ZINC", "url": "" }, { "id": "HMDB0062644", "database": "HMDB Metabolite", "url": "" }, { "id": "C02567", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-141327", "participant_name": "3AAPNAL [peroxisomal matrix]", "crossref": [ { "id": "30322", "database": "ChEBI", "url": "" }, { "id": "ZINC000013542048", "database": "ZINC", "url": "" }, { "id": "HMDB0012880", "database": "HMDB Metabolite", "url": "" }, { "id": "8146179", "database": "PubChem Substance", "url": "" } ] }, { "participant_id": "R-ALL-141349", "participant_name": "NASPM [peroxisomal matrix]", "crossref": [ { "id": "58324", "database": "ChEBI", "url": "" }, { "id": "ZINC000001532698", "database": "ZINC", "url": "" }, { "id": "C00612", "database": "COMPOUND", "url": "" } ] }, { "participant_id": "R-ALL-141350", "participant_name": "PTCN [peroxisomal matrix]", "crossref": [ { "id": "C00134", "database": "COMPOUND", "url": "" }, { "id": "326268", "database": "ChEBI", "url": "" }, { "id": "ZINC000005828633", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "B8JJQ4", "gene_name": "paox", "activity": [ { "ec_number": "1.5.3.13", "activity": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "B8JJQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8JJQ4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JJQ4" }, { "id": "PF01593", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF01593" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Amine oxidase", "eco_id": "ECO_0000259", "start_pos": 21, "end_pos": 496, "start_aa": "Ile", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "1.5.3.13", "ec_name": "N(1)-acetylspermine + O2 + H2O = 3-acetamidopropanal + spermidine + H2O2.", "evidence": [ { "id": "1.5.3.13", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:1.5.3.13" }, { "id": "1.5.3.13", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=1.5.3.13" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 251, "end_pos": 253 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JKA1-1", "uniprot_ac": "B8JKA1", "uniprot_id": "B8JKA1_DANRE", "mass": { "chemical_mass": 39071.0, "monoisotopic_mass": 39071.0 }, "refseq": { "ac": "NP_001139097", "name": "2-oxoglutarate receptor 1a.2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139097" }, "gene_names": [ { "name": "oxgr1a.2", "type": "recommended", "evidence": [ { "id": "B8JKA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKA1" } ] }, { "name": "oxgr1a.2", "type": "synonym", "evidence": [ { "id": "NP_001139097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139097" } ] }, { "name": "si:dkey-181l4.2", "type": "synonym", "evidence": [ { "id": "NP_001139097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139097" }, { "id": "B8JKA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKA1" } ] } ], "protein_names": [ { "name": "2-oxoglutarate receptor 1a.2", "type": "synonym", "evidence": [ { "id": "NP_001139097", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139097" }, { "id": "B8JKA1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKA1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000001.1. 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"https://www.ncbi.nlm.nih.gov/gene/100005578", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000276", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000276", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100005578", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005578", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "GPMLSMI", "url": "https://omabrowser.org/oma/group/GPMLSMI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JKA2", "url": "https://www.orthodb.org/?gene=B8JKA2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24231", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24231", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24231:SF15", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24231:SF15", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00001", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00001", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-373076", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-373076", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-418594", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-418594", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001139100", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139100", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JKA2", "url": "https://www.uniprot.org/uniprotkb/B8JKA2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JKA2-1", "url": "https://www.uniprot.org/uniprotkb/B8JKA2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090312-23", "url": "https://zfin.org/ZDB-GENE-090312-23", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSLNPYYGLTNTSNDNCTDVDNLVKRYYLPTMYAIICVVGAIGNITALLVFVLRIRPWRSSTIIMVNLIFTDLLLIISLPIFVYYYVLNDSWTLGITMCRFSRFDFHFNLYGSILALTCISVIRYVVIVHPQHAENISRKRWGIMSCMLFWIITVVELSPIFNLFATVEIDNKTYCLDFASNDPQSVWPYSWVLTVLGFLVPLVVVCVCYWRIIEKLKEGPHTGSTSRLLARRVIVLIITCFAVCFLPYHVLRAFRVYTRLTPETNCMLDHGVHAAYIISRPIAVLNIIFNMVLYTMQGGNFKQAFVELFKCKKLKSKTERTVEMAVIN", "length": 329, "header": "tr|B8JKA2-1|B8JKA2_DANRE Isoform 1 of 2-oxoglutarate receptor 1a.3 OS=Danio rerio OX=7955 GN=oxgr1a.3 PE=4 SV=1 CANONICAL=B8JKA2-1" }, "isoforms": [ { "isoform_ac": "B8JKA2-1", "url": "https://www.uniprot.org/uniprotkb/B8JKA2/entry#B8JKA2-1", "sequence": { "sequence": "MSLNPYYGLTNTSNDNCTDVDNLVKRYYLPTMYAIICVVGAIGNITALLVFVLRIRPWRSSTIIMVNLIFTDLLLIISLPIFVYYYVLNDSWTLGITMCRFSRFDFHFNLYGSILALTCISVIRYVVIVHPQHAENISRKRWGIMSCMLFWIITVVELSPIFNLFATVEIDNKTYCLDFASNDPQSVWPYSWVLTVLGFLVPLVVVCVCYWRIIEKLKEGPHTGSTSRLLARRVIVLIITCFAVCFLPYHVLRAFRVYTRLTPETNCMLDHGVHAAYIISRPIAVLNIIFNMVLYTMQGGNFKQAFVELFKCKKLKSKTERTVEMAVIN", "length": 329, "header": "tr|B8JKA2-1|B8JKA2_DANRE Isoform 1 of 2-oxoglutarate receptor 1a.3 OS=Danio rerio OX=7955 GN=oxgr1a.3 PE=4 SV=1 CANONICAL=B8JKA2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "B8JKA2", "url": "https://www.uniprot.org/uniprotkb/B8JKA2" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] } ], "pathway": [ { "id": "dre:100005578", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005578", "resource": "KEGG Pathway" }, { "id": "R-DRE-373076", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-373076", "resource": "Reactome", "description": "Class A/1 (Rhodopsin-like receptors)" }, { "id": "R-DRE-418594", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-418594", "resource": "Reactome", "description": "G alpha (i) signalling events" } ], "orthologs": [ { "uniprot_canonical_ac": "B8JKA1-1", "protein_name": "2-oxoglutarate receptor 1a.2", "gene_name": "oxgr1a.2", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSGNLYYDMTNTSSDNCTDVDSKMKRYYLPAMYGAIFIVGVIGNITALLVYLLKVRPWKSSTIIMVNLVLTDLLFMISLPFLVYYYVLNDSWTLGITVCRFARFIFHFNLYGSILFLSCVSIFRYVAIVHPQHSHKIRRKRWGVVSCVLVWVITLAELSPILYVLDTVDLNNETHCSDFASNNPQRVWPYSWVLTVLGYLVPLMVVCACYWRIIVELKKGPHMGSTKRVRARRLIVLILTCFTICFLPYHVLRAFRVYTRLTPGMNCMLDQGIHVAYIISRPIAVLNIIFNLPLYTLSDDSFKQAFVELFKCDKLKSSNEKTTGDDLPTHNQQYKQEE", "length": 338 }, "evidence": [ { "id": "MGI:2685145", "url": "https://alliancegenome.org/gene/MGI:2685145#orthology", "database": "AGR" }, { "id": "HGNC:4531", "url": "https://alliancegenome.org/gene/HGNC:4531#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q6IYF8-1", "protein_name": "2-oxoglutarate receptor 1", "gene_name": "Oxgr1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIEPLDSPASDSDFLDYPSALGNCTDEQISFKMQYLPVIYSIIFLVGFPGNTVAISIYIFKMRPWRGSTVIMLNLALTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFGFHFNLYSSILFLTCFSLFRYVVIIHPMSCFSIQKTRWAVVACAGVWVISLVAVMPMTFLITSTTRTNRSACLDLTSSDDLTTIKWYNLILTATTFCLPLVIVTLCYTTIISTLTHGPRTHSCFKQKARRLTILLLLVFYICFLPFHILRVIRIESRLLSISCSIESHIHEAYIVSRPLAALNTFGNLLLYVVVSNNFQQAFCSIVRCKASGDLEQGKKDSCSNNP", "length": 337 }, "evidence": [ { "id": "MGI:2685145", "url": "https://alliancegenome.org/gene/MGI:2685145#orthology", "database": "AGR" }, { "id": "HGNC:4531", "url": "https://alliancegenome.org/gene/HGNC:4531#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-23#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6Y1R5-1", "protein_name": "2-oxoglutarate receptor 1", "gene_name": "Oxgr1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIETLDSPANDSDFLDYITALENCTDEQISFKMQYLPVIYSIIFLVGFPGNTVAISIYVFKMRPWKSSTIIMLNLALTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFGFHFNLYSSILFLTCFSLFRYIVIIHPMSCFSIQKTRWAVVACAGVWVISLVAVMPMTFLITSTTRTNRSACLDLTSSDDLTTIKWYNLILTATTFCLPLLIVTLCYTTIISTLTHGPRTHSCFKQKARRLTILLLLVFYVCFLPFHILRVIRIESRLLSISCSIESHIHEAYIVSRPLAALNTFGNLLLYVVVSNNFQQAFCSAVRCKAIGDLEQAKKDSCSNNP", "length": 337 }, "evidence": [ { "id": "MGI:2685145", "url": "https://alliancegenome.org/gene/MGI:2685145#orthology", "database": "AGR" }, { "id": "HGNC:4531", "url": "https://alliancegenome.org/gene/HGNC:4531#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q96P68-1", "protein_name": "2-oxoglutarate receptor 1", "gene_name": "OXGR1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MNEPLDYLANASDFPDYAAAFGNCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIFKMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSSILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNRSACLDLTSSDELNTIKWYNLILTATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKARRLTILLLLAFYVCFLPFHILRVIRIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLLLYVVVSDNFQQAVCSTVRCKVSGNLEQAKKISYSNNP", "length": 337 }, "evidence": [ { "id": "MGI:2685145", "url": "https://alliancegenome.org/gene/MGI:2685145#orthology", "database": "AGR" }, { "id": "HGNC:4531", "url": "https://alliancegenome.org/gene/HGNC:4531#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-23#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "G protein-coupled receptor activity", "id": "GO:0004930", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004930", "evidence": [ { "database": "UniProtKB", "id": "B8JKA2", "url": "https://www.uniprot.org/uniprotkb/B8JKA2" } ], "pmid": "" }, { "name": "signaling receptor activity", "id": "GO:0038023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038023", "evidence": [ { "database": "UniProtKB", "id": "B8JKA2", "url": "https://www.uniprot.org/uniprotkb/B8JKA2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B8JKA2", "url": "https://www.uniprot.org/uniprotkb/B8JKA2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G protein-coupled receptor signaling pathway", "id": "GO:0007186", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007186", "evidence": [ { "database": "UniProtKB", "id": "B8JKA2", "url": "https://www.uniprot.org/uniprotkb/B8JKA2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 11, "end_pos": 13, "annotation": "n_glycosylation_sequon" }, { "start_pos": 136, "end_pos": 138, "annotation": "n_glycosylation_sequon" }, { "start_pos": 16, "end_pos": 18, "annotation": "n_glycosylation_sequon" }, { "start_pos": 172, "end_pos": 174, "annotation": "n_glycosylation_sequon" }, { "start_pos": 44, "end_pos": 46, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8JKA2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKA2" }, { "id": "PS50262", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50262" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "G-protein coupled receptors family 1 profile", "eco_id": "ECO_0000259", "start_pos": 43, "end_pos": 295, "start_aa": "Gly", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 11, "end_pos": 13 }, { "start_pos": 136, "end_pos": 138 }, { "start_pos": 16, "end_pos": 18 }, { "start_pos": 172, "end_pos": 174 }, { "start_pos": 44, "end_pos": 46 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JKE1-1", "uniprot_ac": "B8JKE1", "uniprot_id": "B8JKE1_DANRE", "mass": { "chemical_mass": 21809.0, "monoisotopic_mass": 21809.0 }, "refseq": { "ac": "NP_001139104", "name": "ciliary neurotrophic factor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139104" }, "gene_names": [ { "name": "cntf", "type": "recommended", "evidence": [ { "id": "B8JKE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ] }, { "name": "cntf", "type": "synonym", "evidence": [ { "id": "NP_001139104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139104" } ] }, { "name": "si:dkey-117m1.3", "type": "synonym", "evidence": [ { "id": "NP_001139104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139104" }, { "id": "B8JKE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ] } ], "protein_names": [ { "name": "Ciliary neurotrophic factor", "type": "synonym", "evidence": [ { "id": "B8JKE1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKE1/entry#names_and_taxonomy" } ] }, { "name": "ciliary neurotrophic factor", "type": "synonym", "evidence": [ { "id": "NP_001139104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139104" } ] }, { "name": "cntf2", "type": "synonym", "evidence": [ { "id": "NP_001139104", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139104" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH585508.1, GDQH01020494.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505379, SAMEA3505387 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000001.1. On Mar 5, 2009 this sequence version replaced XP_001922827.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications.", "evidence": [ { "database": "RefSeq", "id": "NP_001139104", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139104" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cntf", "url": "https://www.uniprot.org/uniprotkb/B8JKE1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-176", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-176", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000074662", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000074662", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100149185", "url": "https://www.ncbi.nlm.nih.gov/gene/100149185", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000151", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000151", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009079", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009079", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100149185", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100149185", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDQQCNE", "url": "https://omabrowser.org/oma/group/QDQQCNE/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JKE1", "url": "https://www.orthodb.org/?gene=B8JKE1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15196", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15196", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15196:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15196:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001139104", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139104", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JKE1-1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-176", "url": "https://zfin.org/ZDB-GENE-090313-176", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAGRGTNGRHGLRGRAGTSAALARLLHKECIQLLKSYRNSESLPSSPVEGGHLISIPPLVPQLSDEEKISILHAALKECLRLLEDVITREDEEFPDEDSEYKRLRKTVRDRLRHLLASTEQMMVDGQKFEAEVKEELDGQATGGSFGLKMWIVRVFQELVHWTGQTSDALSSLPAEKEKAPVSQRTRRGAGKLRK", "length": 195, "header": "tr|B8JKE1-1|B8JKE1_DANRE Isoform 1 of Ciliary neurotrophic factor OS=Danio rerio OX=7955 GN=cntf PE=4 SV=1 CANONICAL=B8JKE1-1" }, "isoforms": [ { "isoform_ac": "B8JKE1-1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1/entry#B8JKE1-1", "sequence": { "sequence": "MAGRGTNGRHGLRGRAGTSAALARLLHKECIQLLKSYRNSESLPSSPVEGGHLISIPPLVPQLSDEEKISILHAALKECLRLLEDVITREDEEFPDEDSEYKRLRKTVRDRLRHLLASTEQMMVDGQKFEAEVKEELDGQATGGSFGLKMWIVRVFQELVHWTGQTSDALSSLPAEKEKAPVSQRTRRGAGKLRK", "length": 195, "header": "tr|B8JKE1-1|B8JKE1_DANRE Isoform 1 of Ciliary neurotrophic factor OS=Danio rerio OX=7955 GN=cntf PE=4 SV=1 CANONICAL=B8JKE1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain.", "journal": "PLoS ONE", "date": "2008", "authors": "Sreenivasan Rajini, Cai Minnie, Bartfai Richard, Wang Xingang, Christoffels Alan, Orban Laszlo", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "reference": [ { "type": "PubMed", "id": "18335061", "url": "https://glygen.org/publication/PubMed/18335061" } ] }, { "title": "Translational profiling of cardiomyocytes identifies an early Jak1/Stat3 injury response required for zebrafish heart regeneration.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2013", "authors": "Fang Yi, Gupta Vikas, Karra Ravi, Holdway Jennifer E, Kikuchi Kazu, Poss Kenneth D", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "reference": [ { "type": "PubMed", "id": "23901114", "url": "https://glygen.org/publication/PubMed/23901114" } ] }, { "title": "Upregulation of leukemia inhibitory factor (LIF) during the early stage of optic nerve regeneration in zebrafish.", "journal": "PLoS ONE", "date": "2014", "authors": "Ogai Kazuhiro, Kuwana Ayaka, Hisano Suguru, Nagashima Mikiko, Koriyama Yoshiki, Sugitani Kayo, Mawatari Kazuhiro, Nakashima Hiroshi, Kato Satoru", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "reference": [ { "type": "PubMed", "id": "25162623", "url": "https://glygen.org/publication/PubMed/25162623" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Zebrafish Regulatory T Cells Mediate Organ-Specific Regenerative Programs.", "journal": "Dev. Cell", "date": "2017", "authors": "Hui Subhra P, Sheng Delicia Z, Sugimoto Kotaro, Gonzalez-Rajal Alvaro, Nakagawa Shinichi, Hesselson Daniel, Kikuchi Kazu", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "reference": [ { "type": "PubMed", "id": "29257949", "url": "https://glygen.org/publication/PubMed/29257949" } ] }, { "title": "Ciliary neurotrophic factor stimulates cardioprotection and the proliferative activity in the adult zebrafish heart.", "journal": "NPJ Regen Med 1", "date": "2019", "authors": "Bise Thomas, de Preux Charles Anne-Sophie, Ja\u017awi\u0144ska Anna", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "reference": [ { "type": "PubMed", "id": "30701084", "url": "https://glygen.org/publication/PubMed/30701084" } ] }, { "title": "Prior Exposure to Immunosuppressors Sensitizes Retinal Microglia and Accelerates Optic Nerve Regeneration in Zebrafish.", "journal": "Mediators Inflamm.", "date": "2019", "authors": "Bollaerts Ilse, Van Houcke Jessie, Beckers An, Lemmens Kim, Vanhunsel Sophie, De Groef Lies, Moons Lieve", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "reference": [ { "type": "PubMed", "id": "30881223", "url": "https://glygen.org/publication/PubMed/30881223" } ] }, { "title": "Interleukin-11 signaling promotes cellular reprogramming and limits fibrotic scarring during tissue regeneration.", "journal": "Sci. Adv.", "date": "2021", "authors": "Allanki Srinivas, Strilic Boris, Scheinberger Lilly, Onderwater Yeszamin L, Marks Alora, G\u00fcnther Stefan, Preussner Jens, Kikhi Khrievono, Looso Mario, Stainier Didier Y R, Reischauer Sven", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "reference": [ { "type": "PubMed", "id": "34516874", "url": "https://glygen.org/publication/PubMed/34516874" } ] }, { "title": "Distinct features of the regenerating heart uncovered through comparative single-cell profiling.", "journal": "Biol. Open", "date": "2024", "authors": "Carey Clayton M, Hollins Hailey L, Schmid Alexis V, Gagnon James A", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "reference": [ { "type": "PubMed", "id": "38526188", "url": "https://glygen.org/publication/PubMed/38526188" } ] } ], "pathway": [ { "id": "dre:100149185", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100149185", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 5, "go_terms": [ { "name": "positive regulation of axon regeneration", "id": "GO:0048680", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048680", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "pmid": "" }, { "name": "ciliary neurotrophic factor-mediated signaling pathway", "id": "GO:0070120", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0070120", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "pmid": "" }, { "name": "astrocyte activation", "id": "GO:0048143", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0048143", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "pmid": "" }, { "name": "negative regulation of neuron apoptotic process", "id": "GO:0043524", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043524", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "pmid": "" }, { "name": "cell surface receptor signaling pathway via JAK-STAT", "id": "GO:0007259", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007259", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "axon", "id": "GO:0030424", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030424", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "pmid": "" }, { "name": "neuronal cell body", "id": "GO:0043025", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0043025", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "pmid": "" }, { "name": "glial cell projection", "id": "GO:0097386", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0097386", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "cytokine activity", "id": "GO:0005125", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005125", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "pmid": "" }, { "name": "growth factor activity", "id": "GO:0008083", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008083", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "pmid": "" }, { "name": "ciliary neurotrophic factor receptor binding", "id": "GO:0005127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005127", "evidence": [ { "database": "UniProtKB", "id": "B8JKE1", "url": "https://www.uniprot.org/uniprotkb/B8JKE1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": 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"sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JKF3-1", "uniprot_ac": "B8JKF3", "uniprot_id": "B8JKF3_DANRE", "mass": { "chemical_mass": 39688.0, "monoisotopic_mass": 39688.0 }, "refseq": { "ac": "NP_001139094", "name": "leucine-rich repeat-containing protein 58a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139094" }, "gene_names": [ { "name": "lrrc58a", "type": "recommended", "evidence": [ { "id": "B8JKF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKF3" } ] }, { "name": "lrrc58a", "type": "synonym", "evidence": [ { "id": "NP_001139094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139094" } ] }, { "name": "si:dkey-100g3.2", "type": "synonym", "evidence": [ { "id": "NP_001139094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139094" }, { "id": "B8JKF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKF3" } ] } ], "protein_names": [ { "name": "Leucine-rich repeat-containing protein 58a", "type": "synonym", "evidence": [ { "id": "B8JKF3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKF3/entry#names_and_taxonomy" } ] }, { "name": "leucine-rich repeat-containing protein 58a", "type": "synonym", "evidence": [ { "id": "NP_001139094", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139094" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01025496.1, GDQQ01000461.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000001.1. On Mar 5, 2009 this sequence version replaced XP_001340809.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001139094", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139094" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JKF3", "url": "https://www.uniprot.org/uniprotkb/B8JKF3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "lrrc58a", "url": "https://www.uniprot.org/uniprotkb/B8JKF3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090312-76", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-76", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000076773", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000076773", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100000656", "url": "https://www.ncbi.nlm.nih.gov/gene/100000656", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050216", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050216", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100000656", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000656", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CIQSIPP", "url": "https://omabrowser.org/oma/group/CIQSIPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JKF3", "url": "https://www.orthodb.org/?gene=B8JKF3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR48051:SF53", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR48051:SF53", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001139094", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001139094", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JKF3", "url": "https://www.uniprot.org/uniprotkb/B8JKF3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JKF3-1", "url": "https://www.uniprot.org/uniprotkb/B8JKF3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090312-76", "url": "https://zfin.org/ZDB-GENE-090312-76", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MARFPSVDDKCAVLHLSRLHLDDLNLDHLADSKRKQIQQLHLTYNRLTLLPTSVCFLSNLEYLDISNNALTVIPDDIMRLKNLKTFVAKNNLLNECSFPKDFDCIRVETLNLSGNRFEDIPAQFLKMTTLQSLSLGGNRLKAIPEEIQNLTSLEMLYLGGNLISSIPPEVAKLTCLRYLVLCDNRIQSVPPQLNKLHSLLSLSLHNNLLTFLPREILSLVHLQELSLRGNPLVVRFIKDMTYDPPSLMELAGRTVKSQNLPFRSCDLPANLIYYLNLASECPNPKCAGVYFDSCVRHIKFVDFCGKYRLPLMHYLCSPQCSSPCSSNPQSDAESEEENSVPADRLQRVLLG", "length": 351, "header": "tr|B8JKF3-1|B8JKF3_DANRE Isoform 1 of Leucine-rich repeat-containing protein 58a OS=Danio rerio OX=7955 GN=lrrc58a PE=4 SV=1 CANONICAL=B8JKF3-1" }, "isoforms": [ { "isoform_ac": "B8JKF3-1", "url": "https://www.uniprot.org/uniprotkb/B8JKF3/entry#B8JKF3-1", "sequence": { "sequence": "MARFPSVDDKCAVLHLSRLHLDDLNLDHLADSKRKQIQQLHLTYNRLTLLPTSVCFLSNLEYLDISNNALTVIPDDIMRLKNLKTFVAKNNLLNECSFPKDFDCIRVETLNLSGNRFEDIPAQFLKMTTLQSLSLGGNRLKAIPEEIQNLTSLEMLYLGGNLISSIPPEVAKLTCLRYLVLCDNRIQSVPPQLNKLHSLLSLSLHNNLLTFLPREILSLVHLQELSLRGNPLVVRFIKDMTYDPPSLMELAGRTVKSQNLPFRSCDLPANLIYYLNLASECPNPKCAGVYFDSCVRHIKFVDFCGKYRLPLMHYLCSPQCSSPCSSNPQSDAESEEENSVPADRLQRVLLG", "length": 351, "header": "tr|B8JKF3-1|B8JKF3_DANRE Isoform 1 of Leucine-rich repeat-containing protein 58a OS=Danio rerio OX=7955 GN=lrrc58a PE=4 SV=1 CANONICAL=B8JKF3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JKF3", "url": "https://www.uniprot.org/uniprotkb/B8JKF3" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:100000656", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100000656", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LTN7-1", "protein_name": "Leucine rich repeat containing 58", "gene_name": "Lrrc58", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEEAALGEAELNWSRLSVSAEALESELEARAEERRGSREALLRLLLPYNRLTSLPRALGSGFPHLQLLDVSGNALTALGPELLTLSGLRTLLARNNRLGGPGSLPKGLGQSPLCRSLQVLNLSGNCFQELPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPELANLPSLNYLVLCDNKIQSVPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDLTYDPPTLLELAARTIKIRSISYTPYDLPGNLLRYLGSASNCPNPKCGGVYFDCCVRQIKFVDFCGKYRLPLMHYLCSPECSSPCSSASHSSTSQSESDSEDEASVAAHRMQKVLLG", "length": 366 }, "evidence": [ { "id": "HGNC:26968", "url": "https://alliancegenome.org/gene/HGNC:26968#orthology", "database": "AGR" }, { "id": "MGI:2443542", "url": "https://alliancegenome.org/gene/MGI:2443542#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E7FF15-1", "protein_name": "Leucine-rich repeat-containing protein 58", "gene_name": "lrrc58b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MEGFEGASSSESVLDLSRLNLSNLSLDSVSEKRRKDTKQLYLCYNRMTFLAESISLFSNLEFLDISNNTLSVICEDITRLTKLKTLIAKNNRLNEFSLPKHFGSMQLEVLNFSGNRFEEMPTQCLQLLRLQSLSLGGNRLKSIPAEIESLTRLELLYLGGNQISTIPAELANLPGLSYLVLCDNRIQSVPPQLNRLYSLRSLSLHNNLLTYLPREILSLVHLQELSLRGNPLVVRFVKDMTYDPPSLLELSGRTIKSKNLLYSHKDLPSHLVTYLDTASKCPNPKCAGVYFDSCVRHIKFVDFCGKYRLPLMHYLCSPECTSPCSSNPQSDADSDDDHSVPVDRLQRVLLG", "length": 351 }, "evidence": [ { "id": "HGNC:26968", "url": "https://alliancegenome.org/gene/HGNC:26968#orthology", "database": "AGR" }, { "id": "MGI:2443542", "url": "https://alliancegenome.org/gene/MGI:2443542#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3UGP9-1", "protein_name": "Leucine-rich repeat-containing protein 58", "gene_name": "Lrrc58", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MEEAALGEAELNWSRLSVSAEALESELEARAEERRGAREALLRLLLPYNRLTSLPRALGGGFPHLQLLDVSGNSLTALGPELLTLSGLRTLLARNNRLGGPGSLPKGLAQSPLCRSLQVLNLSGNCFQELPASLLELRALQTLSLGGNQLQSIPAEIENLRSLECLYLGGNFIKEIPPELANLPSLNYLVLCDNKIQSVPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDLTYDPPTLLELAARTIKIRSISYTPYDLPGNLLRYLGSASNCPNPKCGGVYFDCCVRQIKFVDFCGKYRLPLMHYLCSPECSSPCSSASHSSTSQSESDSEDEASVAAHRMQKVLLG", "length": 366 }, "evidence": [ { "id": "HGNC:26968", "url": "https://alliancegenome.org/gene/HGNC:26968#orthology", "database": "AGR" }, { "id": "MGI:2443542", "url": "https://alliancegenome.org/gene/MGI:2443542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-76", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-76#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96CX6-1", "protein_name": "Leucine-rich repeat-containing protein 58", "gene_name": "LRRC58", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MEEAGAAVVTAGEAELNWSRLSVSTETLESELEARGEERRGAREALLRLLLPHNRLVSLPRALGSGFPHLQLLDVSGNALTALGPELLALRGLRTLLAKNNRLGGPSALPKGLAQSPLCRSLQVLNLSGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLLTYLPREILNLIHLEELSLRGNPLVVRFVRDLTYDPPTLLELAARTIKIRNISYTPYDLPGNLLRYLGSASNCPNPKCGGVYFDCCVRQIKFVDFCGKYRLPLMHYLCSPECSSPCSSASHSSTSQSESDSEDEASVAARRMQKVLLG", "length": 371 }, "evidence": [ { "id": "HGNC:26968", "url": "https://alliancegenome.org/gene/HGNC:26968#orthology", "database": "AGR" }, { "id": "MGI:2443542", "url": "https://alliancegenome.org/gene/MGI:2443542#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090312-76", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-76#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9W2U2-1", "protein_name": "Disease resistance R13L4/SHOC-2-like LRR domain-containing protein", "gene_name": "CT7080", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEVYTSDSSDTDSREQKTLDFGRMSLDLVTLEDHLASPQKALLKSSGDIETMLLNHNRLVGLPRLLLQFGNLKILDLSSNAITTLPDAVCQLPLVTLIAKNNLLTNASLPKSLLTKMANGNGNGNATGGTNSTLKELNLSGNQLTHFPEQVTELRHLKYLYLGGNKISSVSKDIWKMQSLHVLSLGGNLISEVPEAVGSLNQLQALVLCDNLIEILPTSIARLKNLKSLLLHKNRLRHLPKDIVALKNLTELSLRDNPLVVRFVQDMALKPPTLLELAGRMVKASGQRPGPYDIPRTLAEYLNSANCCVNPNCKGVFFDNRVEHIKFVDFCGKYRVPLLQYLCSSKCIEPEQPAARGSSVPAASASSGFMMRKVLLG", "length": 377 }, "evidence": [ { "id": "HGNC:26968", "url": "https://alliancegenome.org/gene/HGNC:26968#orthology", "database": "AGR" }, { "id": "MGI:2443542", "url": "https://alliancegenome.org/gene/MGI:2443542#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "intracellular signal transduction", "id": "GO:0035556", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0035556", "evidence": [ { "database": "UniProtKB", "id": "B8JKF3", "url": "https://www.uniprot.org/uniprotkb/B8JKF3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 111, "end_pos": 113, "annotation": "n_glycosylation_sequon" }, { "start_pos": 149, "end_pos": 151, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 111, "end_pos": 113 }, { "start_pos": 149, "end_pos": 151 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JKI7-1", "uniprot_ac": "B8JKI7", "uniprot_id": "B8JKI7_DANRE", "mass": { "chemical_mass": 129105.0, "monoisotopic_mass": 129105.0 }, "refseq": { "ac": "XP_001919775", "name": "transcriptional activator MN1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919775" }, "gene_names": [ { "name": "mn1b", "type": "recommended", "evidence": [ { "id": "B8JKI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKI7" } ] }, { "name": "mn1b", "type": "synonym", "evidence": [ { "id": "XP_001919775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919775" } ] } ], "protein_names": [ { "name": "Transcriptional activator MN1", "type": "synonym", "evidence": [ { "id": "B8JKI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKI7/entry#names_and_taxonomy" } ] }, { "name": "transcriptional activator MN1", "type": "synonym", "evidence": [ { "id": "XP_001919775", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919775" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133180) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_001919775.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001919775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919775" } ] } ], "disease": [ { "disease_id": "DOID:3565", "recommended_name": { "id": "DOID:3565", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3565", "name": "meningioma", "description": "A central nervous system cancer that are manifested in the central nervous system and arise from the arachnoid cap cells of the arachnoid villi in the meninges." }, "synonyms": [ { "id": "DOID:3565", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3565", "name": "meningeal neoplasm", "description": "" }, { "id": "DOID:3565", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3565", "name": "meningothelial cell tumor", "description": "" }, { "id": "DOID:3565", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3565", "name": "neoplasm of the meninges", "description": "" }, { "id": "DOID:3565", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:3565", "name": "primary Meningeal tumor", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "3565", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:3565" } ] }, { "disease_id": "DOID:4586", "recommended_name": { "id": "DOID:4586", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:4586", "name": "familial meningioma", "description": "" }, "synonyms": [ { "id": "MONDO:0011789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011789", "name": "familial meningioma", "description": "A meningioma that is transmitted from the parents to an offspring." }, { "id": "MONDO:0011789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011789", "name": "meningioma", "description": "" }, { "id": "MONDO:0011789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011789", "name": "familial meningioma", "description": "" }, { "id": "MONDO:0011789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011789", "name": "hereditary meningioma", "description": "" }, { "id": "MONDO:0011789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011789", "name": "hereditary meningioma (disease)", "description": "" }, { "id": "MONDO:0011789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011789", "name": "meningioma, NF2-related, somatic", "description": "" }, { "id": "MONDO:0011789", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0011789", "name": "meningioma, SIS-related", "description": "" }, { "id": "MIM:607174", "resource": "MIM", "url": "https://www.omim.org/entry/607174", "name": "Meningioma", "description": "Meningioma" } ], "unlinked_id_list": [], "evidence": [ { "id": "4586", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:4586" } ] }, { "disease_id": "DOID:8692", "recommended_name": { "id": "DOID:8692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8692", "name": "myeloid leukemia", "description": "A leukemia that is located_in myeloid tissue." }, "synonyms": [ { "id": "DOID:8692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8692", "name": "Non-Lymphocytic Leukemia", "description": "" }, { "id": "DOID:8692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8692", "name": "leukaemia myelogenous", "description": "" }, { "id": "DOID:8692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8692", "name": "leukemia myelogenous", "description": "" }, { "id": "DOID:8692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8692", "name": "myeloid granulocytic leukaemia", "description": "" }, { "id": "DOID:8692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8692", "name": "myeloid granulocytic leukemia", "description": "" }, { "id": "DOID:8692", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8692", "name": "myeloid leukaemia", "description": "" } ], "unlinked_id_list": [ "DOID:8527" ], "evidence": [ { "id": "8692", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8692" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JKI7", "url": "https://www.uniprot.org/uniprotkb/B8JKI7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mn1b", "url": "https://www.uniprot.org/uniprotkb/B8JKI7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080917-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080917-23", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000079248", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000079248", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "572077", "url": "https://www.ncbi.nlm.nih.gov/gene/572077", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:572077", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:572077", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QESAWFS", "url": "https://omabrowser.org/oma/group/QESAWFS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JKI7", "url": "https://www.orthodb.org/?gene=B8JKI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR15821", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15821", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR15821:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR15821:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_001919775", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001919775", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JKI7", "url": "https://www.uniprot.org/uniprotkb/B8JKI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JKI7-1", "url": "https://www.uniprot.org/uniprotkb/B8JKI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080917-23", "url": "https://zfin.org/ZDB-GENE-080917-23", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MFELEQFGPQINNRNFGHTEKNFNKPKVSMNSHYKSPGFHTGGSQNTAEPGMGPLNETPVIEMNINMSRGEQYGGFQRGHSELHTGNLQQQPSMHGFFNPQQPHNHSHGHQTHPHQHFGGNFGPEPGSSCLHSGRVMGYNSSMGLQQGFTEGFDSLSEGQSADGGFSQQQQRTSSMSDFQHHGPPSGNHPVPAPCLPLDQSPNRAASFHGLSSSSSSSESHNLEPRRMPPPAAVEGLDYSFPNEPSSRHFDVPVYSPSESDSQLSHFGTGRQVPGSNFPGNTGLSRAPGMQGIAKEHPHAPPQQQQPSAQHSVFFERFGGGRKIPVGIEPGARHPLMQQQQPGLIGRQNTCPPSLPQPPLSETASANVGMQEGGVMMPGQHNQFEYPIHRPENRRIHSYGDPIFNMQQQPPPPQQPPNQRLQHFDSPYLNMGKRPRFDFPNATHGRESCGSWNSAMENNLSPAAYPGLPGEFTPPVTDGFSTGPSLQLTGSEQQSMQQQQNAAMMIKQMASRSQQQRMRQPSLQQLGHHNDVSQGPLGPGGPVGGMPQSSFERENGGRMVNFDGRSPHMTMESGWFPGPHPPGEMLGHRMGSSGEMGDRDIQQNGPGMMFRAGVSGMGMQESMRVPGEGHVQPLLSPNIHSQFNSGMGSLSQMQSPSAGVGLPNTPSERRSNDFPGPPMGGPSQFQYGGSNRQGASHGNSQGVNTSPGSFTCQSDFPTSQRSSVSKLGGLSLGNFSKTNGKDNVFGQSCLAALSTACQNMIASLGAPNLNVTFNKKTQAEGKRKLSQTEQDLNNSAVNGTGNTGTEYFPSLTAPQNGQMPPAGNSNAKPLSQNQTVQGEASALSPNFNMDTTPCSEGKAATGSGRGRGRRKRDSGHVSPGIFFPSENSNPVVSPSQQVSSAERSTGTPHEKPHTSPSWGKGGDLLLGDQSDLMSSLDSGIQSASKSEVCSPRMDFTDDAVVTHYSNEDEVSSSSDAQSSVKPGCSPLLGSPKMPNGLMSGQKGQGLSNQTTSTSDGFGGAGHPGTPGMEQVRTPSSTSGQDEIHPLEILQAQIQLQRQQFSISEDQPLAVNNNKKSSELGDGELASCGPDAEKSSVGTIDLDTLMAEQHATWYVPSDKCLLEDSEEEKSTWEKNKAQATIKEEADLTQNKSGGGAGSSGTAGGMGSHLQCLSVHCTDELGESKGRGGPVPSWRSLHSDISNRFGTFVAALT", "length": 1211, "header": "tr|B8JKI7-1|B8JKI7_DANRE Isoform 1 of Transcriptional activator MN1 OS=Danio rerio OX=7955 GN=mn1b PE=4 SV=1 CANONICAL=B8JKI7-1" }, "isoforms": [ { "isoform_ac": "B8JKI7-1", "url": "https://www.uniprot.org/uniprotkb/B8JKI7/entry#B8JKI7-1", "sequence": { "sequence": "MFELEQFGPQINNRNFGHTEKNFNKPKVSMNSHYKSPGFHTGGSQNTAEPGMGPLNETPVIEMNINMSRGEQYGGFQRGHSELHTGNLQQQPSMHGFFNPQQPHNHSHGHQTHPHQHFGGNFGPEPGSSCLHSGRVMGYNSSMGLQQGFTEGFDSLSEGQSADGGFSQQQQRTSSMSDFQHHGPPSGNHPVPAPCLPLDQSPNRAASFHGLSSSSSSSESHNLEPRRMPPPAAVEGLDYSFPNEPSSRHFDVPVYSPSESDSQLSHFGTGRQVPGSNFPGNTGLSRAPGMQGIAKEHPHAPPQQQQPSAQHSVFFERFGGGRKIPVGIEPGARHPLMQQQQPGLIGRQNTCPPSLPQPPLSETASANVGMQEGGVMMPGQHNQFEYPIHRPENRRIHSYGDPIFNMQQQPPPPQQPPNQRLQHFDSPYLNMGKRPRFDFPNATHGRESCGSWNSAMENNLSPAAYPGLPGEFTPPVTDGFSTGPSLQLTGSEQQSMQQQQNAAMMIKQMASRSQQQRMRQPSLQQLGHHNDVSQGPLGPGGPVGGMPQSSFERENGGRMVNFDGRSPHMTMESGWFPGPHPPGEMLGHRMGSSGEMGDRDIQQNGPGMMFRAGVSGMGMQESMRVPGEGHVQPLLSPNIHSQFNSGMGSLSQMQSPSAGVGLPNTPSERRSNDFPGPPMGGPSQFQYGGSNRQGASHGNSQGVNTSPGSFTCQSDFPTSQRSSVSKLGGLSLGNFSKTNGKDNVFGQSCLAALSTACQNMIASLGAPNLNVTFNKKTQAEGKRKLSQTEQDLNNSAVNGTGNTGTEYFPSLTAPQNGQMPPAGNSNAKPLSQNQTVQGEASALSPNFNMDTTPCSEGKAATGSGRGRGRRKRDSGHVSPGIFFPSENSNPVVSPSQQVSSAERSTGTPHEKPHTSPSWGKGGDLLLGDQSDLMSSLDSGIQSASKSEVCSPRMDFTDDAVVTHYSNEDEVSSSSDAQSSVKPGCSPLLGSPKMPNGLMSGQKGQGLSNQTTSTSDGFGGAGHPGTPGMEQVRTPSSTSGQDEIHPLEILQAQIQLQRQQFSISEDQPLAVNNNKKSSELGDGELASCGPDAEKSSVGTIDLDTLMAEQHATWYVPSDKCLLEDSEEEKSTWEKNKAQATIKEEADLTQNKSGGGAGSSGTAGGMGSHLQCLSVHCTDELGESKGRGGPVPSWRSLHSDISNRFGTFVAALT", "length": 1211, "header": "tr|B8JKI7-1|B8JKI7_DANRE Isoform 1 of Transcriptional activator MN1 OS=Danio rerio OX=7955 GN=mn1b PE=4 SV=1 CANONICAL=B8JKI7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:572077", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:572077", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ACD6B6L5-1", "protein_name": "Transcriptional activator MN1", "gene_name": "mn1a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MNSNYNSAGFHMKGPSVAVEPMMGPLNESPMQGLNFVSNRDQYGFQTHGHGDMLGMGVQPQHQLHMQGPFNHQPPNHDQHSHLYQDSVPSCLHGDRHMGFSSTNAGHPHMFEGGFSQQLAEPQSRECISQQQQQRMAAMPEFQPHGHPNGNHAVPAPCLPLDQSPNRAASFHGLPSSSPETHRLEHYRLFPQGRMGGSEHCFPCDPLTGNFDMTGFSTADSSEHKLPYCETGNQVVGGNFSTCNRSGSRGPMMGSSKVDQQLPQQNVFSDRFGNRGKMDPGVNTRHHLMAQQRPGPVVRQNPGSPALPRFYHTPDFVANNTDVQGGGPMVHVQHGHLDRPIHRLNNHNMHPFGEPVFDVPQLAPQPPHHLSSLPYLNMAKRPRFDLPNGSAGESCSPLSHSLHNRPSLENHLSPSAFPSPMGDFTSHVTDGFPSGPLPLSSGPQQQQQQQQRRQNAAMMIKQMASRSQQQRMRQPDLQQLNLHGDVTSNGMVCRGPLGSVSQSNFEKKHNFHGNFDSPHLPQENSWFPEPQQHCRETNTHALEQAENGHNIIFRPSVTSMDMQSLNSPGAHHPFENNVSNPLQMQSPDESNMQSGAPTDRRPAEFGGMVMRRQHSFPPGGPSQQGAPQSNPPGFSSSPGNYPAHPEYLSSQHLSVNKLGALSLGNLNKASTKDSVFGQSCLAALSTACQNMIASLGAPNLNVTFNKKSQNEAKRKAGQVEQDINSSGSSGPGAEYFQSNASQNSQTPCSGNNNNTMVGQSGTGQMVKREASTLSPNDSMESGCEGKMATGNGKGRGKKRRDSGHISPGNFSPPSGGNPVVSPGQQGSNLSMGMESRGKTPERTLVSPSFGKPDLATSMDSGIQSVGKSDGVSPCMDYLDDASPNYSTEDPRPCRAGVKCNSENRASYADASCMEQVRTPLSNTGQDEVHPLEILQAQIQLQRQQFSISEDQPMGGKTSKKADCQASLNGECTLANSSPVTGKSSVNTIDLDSLMTEQHATWYVPGNKALIEDPSNDKCLGYWERARGQSDNKEGHG", "length": 1036 }, "evidence": [ { "id": "MGI:1261813", "url": "https://alliancegenome.org/gene/MGI:1261813#orthology", "database": "AGR" }, { "id": "HGNC:7180", "url": "https://alliancegenome.org/gene/HGNC:7180#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3YWE6-1", "protein_name": "Transcriptional activator MN1", "gene_name": "Mn1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MFGLDQFEPQINSRHAGQGEGNFNEAGLSMNAHFKAPAFHAGPPTGPVDPAISALGEPPILGLNMEPYGFHARSHSELHAGGLQAQPVHGFFGGQQPHHSHPGGHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAESYEHMAESQGPEGFGPQRPGNLPDFHSSGTSGHAVPAPCLPLDQSPNRAASFHGLSASSGSDSHSLEPRRVTNQGAVDSLEYNYPSEPPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRASGMVGLSKMHSQPPQPPPQQQQPQHGVFFERFGGARKMPVGLEPAVGSRHPLMQPPQQAPPPPQQPPPQQQPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGTLDNQLSPSAYPGLPGEFTPPVPDSFSSGPPLQHPGPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGSVGGLAQTNFEREGGSAGAGRLSGFEQQAPHLAQESAWFPGPHPPGDLLPRRMGGAGLPTDCGPHDPALAPPPAPGGSGVLFRGSLQEPLRMPGEGHVPALASPGLQFGGSLAGLGQLQSPGAGVGLPNAPSERRPPPPDFPAPALGGQPGFPFGSGSRQATPHSAPGVNSPPSAGSGSSGAGGGAYPPQPDFQPSQRNSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNEPDSAVAAGNPGSDYFPGGTTPGAPGPGGPSGTSGGGSKASGPPNPPIQGDSTSLSPNYTLESTSGNDGKPVPGGSGRGRGRRKRDSGHVSPGTFFDKYSTAPDSGGAPGVSPGQQQAPGSAAGGSSVNEARGPTPHEKALTSPSWGKGAELLLGDQPDLMASLDSTAKSDGSSPHVGEFASDEVSTSYANEDEVSSSSDNTTALAKASRSPLVTSSPKLPPRGVGAGEHTPKASALGLGILSTSTSTPDSYGGGVGTGHPGTPGLEQVRTPTSSSGAQPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGSKKAECAVGASGAQNGDSELGSCCSEAVKSAMSTIDLDSLMAEHSTTWYMPPDKALVDGGDEDKTLAPWEKAKSQNPNNKEAHDHPTNKASATQPGSHLQCLTVHCTDGDPKARTSVPTWRSLHSDISNRFGTFVAALT", "length": 1297 }, "evidence": [ { "id": "MGI:1261813", "url": "https://alliancegenome.org/gene/MGI:1261813#orthology", "database": "AGR" }, { "id": "HGNC:7180", "url": "https://alliancegenome.org/gene/HGNC:7180#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080917-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080917-23#orthology", "database": "AGR" }, { "id": "B8JKI7", "url": "https://omabrowser.org/oma/group/B8JKI7/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "D4AAP6-1", "protein_name": "MN1 proto-oncogene, transcriptional regulator", "gene_name": "Mn1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MFGLDQFEPQINSRHAGQGEGNFNEAGLSMNAHFKAPAFHAGPPPGPVDPAISALGEPPILGLNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHSHPGGHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAASGLGSQPPFAESYEHMAESQGPEGFGPQRPGNLPDFHSSGTSGHAVPAPCLPLDQSPNRAASFHGLSASSGSDSHSLEPRRVTNQGAVDSLEYNYPSEPPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRASGMVGLSKMHGQPPQPPPPQQQPQHGVFFERFGGARKMPVGLEPAVGSRHPLMQPPQQAPPPPQQQPQQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSTGVDRCASWNGSMHNGTLDNQLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPGPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQHQRLRQPNLAQLGHPGDVGQGGLVHGGSVSGLAQTNFEREGGSTGAGRLGGFEQQAPHLAQESAWFPGPHPPGDLLPRRMGSAGLPADCGPHDPGLAPPPAPGGSGVLFRGSLQEPLRMPGEGHVPALASPGLQFGSSLAGLGQLQSPGAGVGLPNAPSERRPPPPDFPAPALGGQPGFPFGSGSRQATPHSAPGVNSPPSAGAGSGSSGAAGGAYPPQPDFQSSQRNSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNEPDSAVAAGNPGSDYFPGGTTPGAPGPGGPSGTSGGGSKASGPPNPPIQGDSTSLSPNYTLESTSGSDGKPVPGGSGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQAPGSAAGGSSVNEARGPTPHEKALTSPSWGKGAELLLGDQPDLMASLDSTAKSDGSSPHVGEFASDEVSTSYANEDEVSSSSDNTTALAKASRSPLVTSSPKLPPRGVGAGEHTPKASALGLGILSTSTSTPDSYGGGVGTGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGSKKTECAVGASGAQNGDSELGSCCSEAVKSAMSTIDLDSLMAEHSTTWYMPPDKALVDGGDDDKTLAPWEKAKSQNPNNKEVHDHPTNKASATQPGSHLQCLTVHCTDGDPKARTSVPTWRSLHSDISNRFGTFVAALT", "length": 1304 }, "evidence": [ { "id": "MGI:1261813", "url": "https://alliancegenome.org/gene/MGI:1261813#orthology", "database": "AGR" }, { "id": "HGNC:7180", "url": "https://alliancegenome.org/gene/HGNC:7180#orthology", "database": "AGR" }, { "id": "B8JKI7", "url": "https://omabrowser.org/oma/group/B8JKI7/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1MG71-1", "protein_name": "MN1 proto-onco, transcriptional regulator", "gene_name": "MN1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MFGLDQFEPQINSRNAGQGERNFNEAGLSMNAHFKAPAFHAGGPPGPVDPAMSGLGEPPILGMNMEPYGFHARSHSELHAGGLQAQPVHGFFGGQQPHHGHPGGHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFTEGYDHMAESQGPESFGPQRPGNLPDFHSSGASGHAVPAPCLPLDQSPNRAASFHGLPASGGSDSHSLEPRRVANQGAVDSLEYNYPGEPPSGHFDMFSPSDSEGQLPHYAAGRQVPGGSFPGASAMPRAAGMVGLSKMHAQQQQQQQQQQQQQQQQQQHGVFFERFGGTRKMPVGLEPGVGSRHPLMQPPQQAPPPPQQPPPQQAPPPPQQPPPQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPNQHAQFEYPIHRLENRSMHPYSEPVFNMQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYSGLPGEFTPPVPDSFPSGPPLQHPAPDHPSLQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHSGPVGGLGQPNFERDSGGAGAGRLGTFEPQAQHLAQESAWFPGPHPPPGDLLPRRMGGSGLPSDCGPHDPGLAPPPPPGGSGVLFRGSLQEPLRMPGEGHVPGLPSPGLQFGGSLASLGQLQSPGAGVGLPSAPSERRPQPPDFTAPALGGQPGFPFGAANRQATPHSGPGVNSPPSAGGGGGSTGGGGGAGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVPGGGGRGRGRRKRDSGHVSPGTFFDKYSAASAPDSGGAPGVSPGQQQAPGAAVGGNSGEVRGAPTPHEKALTSPSWGKGAELLLGDQPDLMASLDGGAKSDSSSPHVGEFASDEVSTSYANEDEVSSSSDNPPALAKASRSPLVTGSPKLPPRGVGTGEHGPKAPPPPLGLGILSTSTSTPDSYGGGGTGHPGTPGLEQVRTPTSSGGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELGSCCSEAVKSAMSTIDLDSLMAEHSATWYMPADKALVDGTEEDKTLAPWEKAKPQNPNSKEAHDLPANKASAPQPGSHLQCLSVHCTDDVGDAKARASVPTWRSLHSDISNRFGTFVAALT", "length": 1309 }, "evidence": [ { "id": "B8JKI7", "url": "https://omabrowser.org/oma/group/B8JKI7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q10571-1", "protein_name": "Transcriptional activator MN1", "gene_name": "MN1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFGLDQFEPQVNSRNAGQGERNFNETGLSMNTHFKAPAFHTGGPPGPVDPAMSALGEPPILGMNMEPYGFHARGHSELHAGGLQAQPVHGFFGGQQPHHGHPGSHHPHQHHPHFGGNFGGPDPGASCLHGGRLLGYGGAAGGLGSQPPFAEGYEHMAESQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSHSLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQVPGGAFPGASAMPRAAGMVGLSKMHAQPPQQQPQQQQQPQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFDFPGSAGVDRCASWNGSMHNGALDNHLSPSAYPGLPGEFTPPVPDSFPSGPPLQHPAPDHQSLQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQQQRLRQPNLAQLGHPGDVGQGGLVHGGPVGGLAQPNFEREGGSTGAGRLGTFEQQAPHLAQESAWFSGPHPPPGDLLPRRMGGSGLPADCGPHDPSLAPPPPPGGSGVLFRGPLQEPMRMPGEGHVPALPSPGLQFGGSLGGLGQLQSPGAGVGLPSAASERRPPPPDFATSALGGQPGFPFGAAGRQSTPHSGPGVNSPPSAGGGGGSSGGGGGGGAYPPQPDFQPSQRTSASKLGALSLGSFNKPSSKDNLFGQSCLAALSTACQNMIASLGAPNLNVTFNKKNPPEGKRKLSQNETDGAAVAGNPGSDYFPGGTAPGAPGPGGPSGTSSSGSKASGPPNPPAQGDGTSLSPNYTLESTSGNDGKPVSGGGGRGRGRRKRDSGHVSPGTFFDKYSAAPDSGGAPGVSPGQQQASGAAVGGSSAGETRGAPTPHEKALTSPSWGKGAELLLGDQPDLIGSLDGGAKSDSSSPNVGEFASDEVSTSYANEDEVSSSSDNPQALVKASRSPLVTGSPKLPPRGVGAGEHGPKAPPPALGLGIMSNSTSTPDSYGGGGGPGHPGTPGLEQVRTPTSSSGAPPPDEIHPLEILQAQIQLQRQQFSISEDQPLGLKGGKKGECAVGASGAQNGDSELGSCCSEAVKSAMSTIDLDSLMAEHSAAWYMPADKALVDSADDDKTLAPWEKAKPQNPNSKEAHDLPANKASASQPGSHLQCLSVHCTDDVGDAKARASVPTWRSLHSDISNRFGTFVAALT", "length": 1320 }, "evidence": [ { "id": "MGI:1261813", "url": "https://alliancegenome.org/gene/MGI:1261813#orthology", "database": "AGR" }, { "id": "HGNC:7180", "url": "https://alliancegenome.org/gene/HGNC:7180#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080917-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080917-23#orthology", "database": "AGR" }, { "id": "B8JKI7", "url": "https://omabrowser.org/oma/group/B8JKI7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "R4GG28-1", "protein_name": "MN1 proto-onco, transcriptional regulator", "gene_name": "MN1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MFGLEQFEPQMSSRSGGQGERGFGQPGLSMSAHFKAPAFPGGGPAAAVDPALGALGEPPLLGMNMSLPGDGYGFPGRGPAELHGAGMQPPVHGFFGGQQPHGGHGGAHHPHQHQHQHQHQPHFGGNFGPDPGASCVHGGRLLGYNGALGGQTAFADGYEHMAESQGAEGFGQQRAGNLPDFQQHSAGASGHAVPAPCLPLDQSPNRAASFHGLPAAGSSEPHGLEQRRLPAQDSLEYNYPGDGPAAHFELPVFSPSEPEGQLPHYGGGRQVPAGGGFAGTALPRAPGMAVAKAQPPPPPPPPPQQPQQQQHGVFFERFGGARKMPASLEPGASARHPLMQQQQPQQPPGLLARQNSCPPAIPRQQQTEANAPNPNLQDNGPIMQNQHAQFEYPIHRLENRNMHPYADPVFNMQHPPPQQPPNQRLQHFDAPYVSVAKRPRFDFPGNPGVERCASWAGGMHGPAMESHLSPTAYPGLPGDFTPPAPDAFGGPLPHGGPEHPALAQRQNAALVMKQMASRSQQRLRPPSLQQLGHHGEVGPPGSLPPPGFEREAAAAARGFDAPAPHLAPDGTWFAGPPPPGELLPRRMAGPGLPAEAAPHELGLQPGGAAVLFRPGAGALGLQEPLRMAGEGPAQALPSPGVHPPFAPAVGGLSQLQSPGGGVALPSAPAERRGPADFAAQPGFPFGAAARQPPAHGNAPALSASPGAYPPPPPEFPPPPPPPRPAASKLGALSLGSFSKPAGKDNVFGQSCLAALSTACQNMIASLGAPNLNVTFNKKSPAEAKRKLSQAEPDPPPPAAPDYFPAGPTAGGGAGKAAPLLPAESSLSPGFALEPAAGGEGKAGGGRGRGRRKRDSGHVSPGTFFEKFSAAEGGGAGVSPGQPAPPAAGGPPGAAGAERGGGTPHDKPLTSPSWGKGGELLLGEQPDLMSSLDSGIQSVTKSDGSSPHVDFADEVSTSYGNEDEVSSSSDNAGPKPTRSPLLGGSPKLPRGEHALLNGQKPLALGLLNTSTSTPDSYGLSSTAGAHPGTPGMEQVRTPTSTSAQDEIHPLEILQAQIQLQRQQFSISEDQPLGLKSKKGECAGQNGDSDLGGCCPEGVKNTMSTIDLDSLMAEHNSTWYLPGEKALMEGQEEDKPMAPWEKPKPPNPSKEAHDLPPSKTSATAQTGSHLQCLSVHCTDDVGEAKGRTAVPTWRSLHSDISNRFGTFVAALT", "length": 1210 }, "evidence": [ { "id": "B8JKI7", "url": "https://omabrowser.org/oma/group/B8JKI7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of DNA-templated transcription", "id": "GO:0006355", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006355", "evidence": [ { "database": "UniProtKB", "id": "B8JKI7", "url": "https://www.uniprot.org/uniprotkb/B8JKI7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 1008, "end_pos": 1010, "annotation": "n_glycosylation_sequon" }, { "start_pos": 105, "end_pos": 107, "annotation": "n_glycosylation_sequon" }, { "start_pos": 1149, "end_pos": 1151, "annotation": "n_glycosylation_sequon" }, { "start_pos": 140, "end_pos": 142, "annotation": "n_glycosylation_sequon" }, { "start_pos": 441, "end_pos": 443, "annotation": "n_glycosylation_sequon" }, { "start_pos": 459, "end_pos": 461, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" }, { "start_pos": 704, "end_pos": 706, "annotation": "n_glycosylation_sequon" }, { "start_pos": 734, "end_pos": 736, "annotation": "n_glycosylation_sequon" }, { "start_pos": 770, "end_pos": 772, "annotation": "n_glycosylation_sequon" }, { "start_pos": 793, "end_pos": 795, "annotation": "n_glycosylation_sequon" }, { "start_pos": 798, "end_pos": 800, "annotation": "n_glycosylation_sequon" }, { "start_pos": 833, "end_pos": 835, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 1008, "end_pos": 1010 }, { "start_pos": 105, "end_pos": 107 }, { "start_pos": 1149, "end_pos": 1151 }, { "start_pos": 140, "end_pos": 142 }, { "start_pos": 441, "end_pos": 443 }, { "start_pos": 459, "end_pos": 461 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 66, "end_pos": 68 }, { "start_pos": 704, "end_pos": 706 }, { "start_pos": 734, "end_pos": 736 }, { "start_pos": 770, "end_pos": 772 }, { "start_pos": 793, "end_pos": 795 }, { "start_pos": 798, "end_pos": 800 }, { "start_pos": 833, "end_pos": 835 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B8JKY8-1", "uniprot_ac": "B8JKY8", "uniprot_id": "B8JKY8_DANRE", "mass": { "chemical_mass": 19372.0, "monoisotopic_mass": 19372.0 }, "refseq": { "ac": "NP_001138290", "name": "gamma-glutamylcyclotransferase a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138290" }, "gene_names": [ { "name": "ggcta", "type": "recommended", "evidence": [ { "id": "B8JKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKY8" } ] }, { "name": "ggcta", "type": "synonym", "evidence": [ { "id": "NP_001138290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138290" } ] }, { "name": "si:ch211-149a19.5", "type": "synonym", "evidence": [ { "id": "NP_001138290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138290" }, { "id": "B8JKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKY8" } ] } ], "protein_names": [ { "name": "4.3.2.9", "type": "synonym", "evidence": [ { "id": "B8JKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKY8/entry#names_and_taxonomy" } ] }, { "name": "Gamma-glutamylcyclotransferase a", "type": "synonym", "evidence": [ { "id": "B8JKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKY8/entry#names_and_taxonomy" } ] }, { "name": "gamma-glutamyl cyclotransferase a", "type": "synonym", "evidence": [ { "id": "NP_001138290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138290" } ] }, { "name": "gamma-glutamylcyclotransferase a", "type": "synonym", "evidence": [ { "id": "NP_001138290", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138290" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH549675.1, BI703315.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000019.1. On Jan 25, 2009 this sequence version replaced XP_001923894.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001138290", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138290" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JKY8", "url": "https://www.uniprot.org/uniprotkb/B8JKY8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ggcta", "url": "https://www.uniprot.org/uniprotkb/B8JKY8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-129", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-129", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000076406", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000076406", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06661", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06661", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100149204", "url": "https://www.ncbi.nlm.nih.gov/gene/100149204", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013024", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013024", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR017939", "url": "https://www.ebi.ac.uk/interpro/entry/IPR017939", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036568", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036568", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100149204", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100149204", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QPEGNVH", "url": "https://omabrowser.org/oma/group/QPEGNVH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JKY8", "url": "https://www.orthodb.org/?gene=B8JKY8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12935", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12935", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12935:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12935:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13772", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13772", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-174403", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-174403", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001138290", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138290", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JKY8", "url": "https://www.uniprot.org/uniprotkb/B8JKY8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JKY8-1", "url": "https://www.uniprot.org/uniprotkb/B8JKY8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-129", "url": "https://zfin.org/ZDB-GENE-081104-129", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSSSDYFMYFAYGSNLLKERLQLKNPSAVFHCVGRIQGYRLDFGLSGDNTNCAWHGGVATIQASEGDEVWGVVWRIDQQNLPSLDRQEQVDEGVYSPLQVKVETKEEPLYCRTYKMNNFTPCSPSPQYKKVVCLGAQQNGLPQNYIQKLLELQTNNYSGSSVLDQITDIQK", "length": 171, "header": "tr|B8JKY8-1|B8JKY8_DANRE Isoform 1 of Gamma-glutamylcyclotransferase a OS=Danio rerio OX=7955 GN=ggcta PE=4 SV=1 CANONICAL=B8JKY8-1" }, "isoforms": [ { "isoform_ac": "B8JKY8-1", "url": "https://www.uniprot.org/uniprotkb/B8JKY8/entry#B8JKY8-1", "sequence": { "sequence": "MSSSDYFMYFAYGSNLLKERLQLKNPSAVFHCVGRIQGYRLDFGLSGDNTNCAWHGGVATIQASEGDEVWGVVWRIDQQNLPSLDRQEQVDEGVYSPLQVKVETKEEPLYCRTYKMNNFTPCSPSPQYKKVVCLGAQQNGLPQNYIQKLLELQTNNYSGSSVLDQITDIQK", "length": 171, "header": "tr|B8JKY8-1|B8JKY8_DANRE Isoform 1 of Gamma-glutamylcyclotransferase a OS=Danio rerio OX=7955 GN=ggcta PE=4 SV=1 CANONICAL=B8JKY8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [ "enzyme" ], "publication": [ { "title": "Evolution of gonadotropin-inhibitory hormone receptor and its ligand.", "journal": "Gen. Comp. Endocrinol.", "date": "2014", "authors": "Ubuka Takayoshi, Tsutsui Kazuyoshi", "evidence": [ { "database": "UniProtKB", "id": "B8JKY8", "url": "https://www.uniprot.org/uniprotkb/B8JKY8" } ], "reference": [ { "type": "PubMed", "id": "25220854", "url": "https://glygen.org/publication/PubMed/25220854" } ] }, { "title": "Embryonic exposure to 10 mug L(-1) lead results in female-specific expression changes in genes associated with nervous system development and function and Alzheimer's disease in aged adult zebrafish brain.", "journal": "Metallomics", "date": "2016", "authors": "Lee Jinyoung, Freeman Jennifer L", "evidence": [ { "database": "UniProtKB", "id": "B8JKY8", "url": "https://www.uniprot.org/uniprotkb/B8JKY8" } ], "reference": [ { "type": "PubMed", "id": "26776728", "url": "https://glygen.org/publication/PubMed/26776728" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "B8JKY8", "url": "https://www.uniprot.org/uniprotkb/B8JKY8" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] } ], "pathway": [ { "id": "dre:100149204", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100149204", "resource": "KEGG Pathway" }, { "id": "R-DRE-174403", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-174403", "resource": "Reactome", "description": "Glutathione synthesis and recycling" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZPV8-1", "protein_name": "Gamma-glutamylcyclotransferase", "gene_name": "Ggct", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSCWRGQVDMASSDCEDHAGQEGETFLYFAYGSNLLTERIHLRNPSAVFCCVARLQDFKLDFGNFQGKMSERWHGGIATIFQSPGDEVWGVVWKMNKSNLSSLDEQEGVKSGVYVVIEIKVTTQQGKDITCRSYLMTNYERAPPSPQYKKVICMGAKENGLPLEYQEKLNVIEPNDYKGKISDEMEDIIKKGEAKLL", "length": 198 }, "evidence": [ { "id": "HGNC:21705", "url": "https://alliancegenome.org/gene/HGNC:21705#orthology", "database": "AGR" }, { "id": "MGI:95700", "url": "https://alliancegenome.org/gene/MGI:95700#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75223-1", "protein_name": "Gamma-glutamylcyclotransferase", "gene_name": "GGCT", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MANSGCKDVTGPDEESFLYFAYGSNLLTERIHLRNPSAAFFCVARLQDFKLDFGNSQGKTSQTWHGGIATIFQSPGDEVWGVVWKMNKSNLNSLDEQEGVKSGMYVVIEVKVATQEGKEITCRSYLMTNYESAPPSPQYKKIICMGAKENGLPLEYQEKLKAIEPNDYTGKVSEEIEDIIKKGETQTL", "length": 188 }, "evidence": [ { "id": "HGNC:21705", "url": "https://alliancegenome.org/gene/HGNC:21705#orthology", "database": "AGR" }, { "id": "MGI:95700", "url": "https://alliancegenome.org/gene/MGI:95700#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-129", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-129#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8IQT0-1", "protein_name": "Gamma-glutamylcyclotransferase", "gene_name": "Dmel\\CG32196", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNLKLHHFTTMATTFFYFGFGSNMLASRIHIQNPTAKRIGVGKLENFRLDFHTGSKNWLGAPATIVPTQGSHVYGAIWEIDMCNLKDLDDQESVPAGVYVPISVPVHLLNTDSSITCRAYHLTNQPQTDLHAGGGQEIIPHDRQPSQTYLKVLVKGATESGVPDEYIEWLRGIKHNGKQVPAMEAKLELDKVQLS", "length": 195 }, "evidence": [ { "id": "HGNC:21705", "url": "https://alliancegenome.org/gene/HGNC:21705#orthology", "database": "AGR" }, { "id": "MGI:95700", "url": "https://alliancegenome.org/gene/MGI:95700#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9D7X8-1", "protein_name": "Gamma-glutamylcyclotransferase", "gene_name": "Ggct", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MASSDCEGHAGQEGETFLYFAYGSNLLTERIHLRNPSAVFCCVARLQDFKLDFGNFQGKMSERWHGGIATIFQSPGDEVWGVVWRMNKSNISSLDEQEGVKSGVYVVIEIKVSTREGKEITCRSYLMTNYESAPPSPQYKKVICMGAKENGLPQEYQEKLKAIEPNEYKGKISDEMEDIIKKGESKLS", "length": 188 }, "evidence": [ { "id": "HGNC:21705", "url": "https://alliancegenome.org/gene/HGNC:21705#orthology", "database": "AGR" }, { "id": "MGI:95700", "url": "https://alliancegenome.org/gene/MGI:95700#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-129", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-129#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VVP9-1", "protein_name": "Gamma-glutamylcyclotransferase", "gene_name": "Dmel\\CG4306", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MNYECLIGVLSCLLVALPKGNCHSISGLNSTLNLPEIRGDQFLYFGFGSNMLIKRIHIQNPSAVRIGPALLPDYRLDFALESAGWSGSVATIVPTQGDHVWGTLWKIDLSNLPDIDSQEGVSQGIYEPRTVYVKLHGESESTPARAYLLTKQPESNLYELPKDSIPLSRQPSKTYLQCLVKGAIESSVPEDYVQRLRSIKHNGQVNSYLERKLELGGVTL", "length": 220 }, "evidence": [ { "id": "HGNC:21705", "url": "https://alliancegenome.org/gene/HGNC:21705#orthology", "database": "AGR" }, { "id": "MGI:95700", "url": "https://alliancegenome.org/gene/MGI:95700#orthology", "database": "AGR" }, { "id": "B8JKY8", "url": "https://omabrowser.org/oma/group/B8JKY8/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "gamma-glutamylcyclotransferase activity", "id": "GO:0003839", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003839", "evidence": [ { "database": "UniProtKB", "id": "B8JKY8", "url": "https://www.uniprot.org/uniprotkb/B8JKY8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 118, "end_pos": 120, "annotation": "n_glycosylation_sequon" }, { "start_pos": 156, "end_pos": 158, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [ { "id": "R-DRE-1247922", "name": "GGCT transforms gGluCys to OPRO", "equation": "", "summary": "This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp", "cellular_location": "cytosol", "input_participant_list": [ "R-ALL-174393" ], "output_participant_list": [], "enzyme_list": [ "B8JKY8-1" ], "evidence": [ { "id": "R-DRE-1247922", "database": "Reactome", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-1247922" } ] } ], "reaction_participants": [ { "participant_id": "R-ALL-174393", "participant_name": "gGluCys [cytosol]", "crossref": [ { "id": "58173", "database": "ChEBI", "url": "" }, { "id": "ZINC000003870040", "database": "ZINC", "url": "" } ] } ], "reaction_enzymes": [ { "uniprot_ac": "B8JKY8", "gene_name": "ggcta", "activity": [ { "ec_number": "4.3.2.9", "activity": "an alpha-(gamma-L-glutamyl)-L-amino acid = 5-oxo-L-proline + an L-alpha-amino acid.", "evidence": [ { "id": "B8JKY8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JKY8" } ] } ] } ], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [ { "ec_number": "4.3.2.9", "ec_name": "an alpha-(gamma-L-glutamyl)-L-amino acid = 5-oxo-L-proline + an L-alpha-amino acid.", "evidence": [ { "id": "4.3.2.9", "database": "Rhea", "url": "https://www.rhea-db.org/rhea/?query=ec:4.3.2.9" }, { "id": "4.3.2.9", "database": "BRENDA Enzymes", "url": "https://www.brenda-enzymes.org/enzyme.php?ecno=4.3.2.9" } ] } ], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 118, "end_pos": 120 }, { "start_pos": 156, "end_pos": 158 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JL57-1", "uniprot_ac": "B8JL57", "uniprot_id": "B8JL57_DANRE", "mass": { "chemical_mass": 20068.0, "monoisotopic_mass": 20068.0 }, "refseq": { "ac": "NP_001243088", "name": "required for excision 1-B domain-containing protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243088" }, "gene_names": [ { "name": "rex1bd", "type": "recommended", "evidence": [ { "id": "B8JL57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JL57" } ] }, { "name": "im:7139388", "type": "synonym", "evidence": [ { "id": "NP_001243088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243088" }, { "id": "B8JL57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JL57" } ] }, { "name": "rex1bd", "type": "synonym", "evidence": [ { "id": "NP_001243088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243088" } ] }, { "name": "si:ch211-87h14.3", "type": "synonym", "evidence": [ { "id": "NP_001243088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243088" }, { "id": "B8JL57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JL57" } ] } ], "protein_names": [ { "name": "Required for excision 1-B domain-containing protein", "type": "synonym", "evidence": [ { "id": "B8JL57", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JL57/entry#names_and_taxonomy" } ] }, { "name": "required for excision 1-B domain-containing protein", "type": "synonym", "evidence": [ { "id": "NP_001243088", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243088" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH607940.1, EH444905.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505390 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000022.1. On or before Jan 12, 2012 this sequence version replaced XP_693023.3, XP_003201081.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001243088", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243088" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JL57", "url": "https://www.uniprot.org/uniprotkb/B8JL57" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rex1bd", "url": "https://www.uniprot.org/uniprotkb/B8JL57", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081031-40", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081031-40", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000073867", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000073867", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "564601", "url": "https://www.ncbi.nlm.nih.gov/gene/564601", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039491", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039491", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564601", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564601", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "VQGLRAW", "url": "https://omabrowser.org/oma/group/VQGLRAW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JL57", "url": "https://www.orthodb.org/?gene=B8JL57", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28309", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28309", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28309:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28309:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14966", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14966", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001243088", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001243088", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JL57", "url": "https://www.uniprot.org/uniprotkb/B8JL57", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JL57-1", "url": "https://www.uniprot.org/uniprotkb/B8JL57-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081031-40", "url": "https://zfin.org/ZDB-GENE-081031-40", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLQCSFISKPMKTPKACFSTMAPSDFKSLVRRFYVLQSERVEAYKLFEEGHEAYLRTGPHYDFEHYKQLVHEITKAFCGISKEVLTIKQQLHQDFDRPDLSEHIDKLQIKEKEKLELTAKLQLTRQSAQDHPEDEDFQEKVREIKQEIIKNTAALSEILQDFKFDSEEPE", "length": 170, "header": "tr|B8JL57-1|B8JL57_DANRE Isoform 1 of Required for excision 1-B domain-containing protein OS=Danio rerio OX=7955 GN=rex1bd PE=1 SV=1 CANONICAL=B8JL57-1" }, "isoforms": [ { "isoform_ac": "B8JL57-1", "url": "https://www.uniprot.org/uniprotkb/B8JL57/entry#B8JL57-1", "sequence": { "sequence": "MLQCSFISKPMKTPKACFSTMAPSDFKSLVRRFYVLQSERVEAYKLFEEGHEAYLRTGPHYDFEHYKQLVHEITKAFCGISKEVLTIKQQLHQDFDRPDLSEHIDKLQIKEKEKLELTAKLQLTRQSAQDHPEDEDFQEKVREIKQEIIKNTAALSEILQDFKFDSEEPE", "length": 170, "header": "tr|B8JL57-1|B8JL57_DANRE Isoform 1 of Required for excision 1-B domain-containing protein OS=Danio rerio OX=7955 GN=rex1bd PE=1 SV=1 CANONICAL=B8JL57-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JL57", "url": "https://www.uniprot.org/uniprotkb/B8JL57" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8JL57", "url": "https://www.uniprot.org/uniprotkb/B8JL57" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:564601", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564601", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AA43-1", "protein_name": "Required for excision 1-B domain containing", "gene_name": "Rex1bd", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLTAATEVLAAADGPGSAEPTWAWRDAPIATLVQRIQQLQNERAQAFRRLDQAHRQYLLSDLHHDFPSYRSVVHEVTQAFAAASCEVLAVEAELAGPRAQPVLARHVRNLQELEQTRLATVRSPPLLQNGAWATTHSQPPRPTTIFATHLGAFGPSPGFSCLPVFPSQILLIYTSPSVKLP", "length": 181 }, "evidence": [ { "id": "RGD:1566239", "url": "https://alliancegenome.org/gene/RGD:1566239#orthology", "database": "AGR" }, { "id": "MGI:1913712", "url": "https://alliancegenome.org/gene/MGI:1913712#orthology", "database": "AGR" }, { "id": "HGNC:26098", "url": "https://alliancegenome.org/gene/HGNC:26098#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081031-40", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081031-40#orthology", "database": "AGR" }, { "id": "B8JL57", "url": "https://omabrowser.org/oma/group/B8JL57/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3H492-1", "protein_name": "Required for excision 1-B domain-containing protein isoform X1", "gene_name": "Rex1bd", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MLTATAEVPAAVDAPASTEPAWAWRDAPISTLVQRIQQLQNERAQAFRRLDQAHRQYLLSGQHHDFPSYRSVVHEVTQAFAAASREVLAVEAELAGPRAQPVLARHVRSLQDLEQTRLATVALLQVMGTPGVSEQEDPEKLHQLKIKVIKTMEAISEVLQELRFDAESAE", "length": 170 }, "evidence": [ { "id": "B8JL57", "url": "https://omabrowser.org/oma/group/B8JL57/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q17Q97-1", "protein_name": "Required for excision 1-B domain-containing protein", "gene_name": "REX1BD", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MITAEAASESTVPAVPGDTAATGVPEHEELVWPWKDAPIRELVQRIHQLQAERAQAFRRLEEGHRQYLSSGPPYDFPRYRSTVHEVTQVFAAASREVLAVEAELAGPRAQPLLASHVRSLQQLEETRLTTVALLQLMGTPELTGQEDSLQMHQLKMKVIKTMEAISEVLQDLRFDAESAE", "length": 180 }, "evidence": [ { "id": "B8JL57", "url": "https://omabrowser.org/oma/group/B8JL57/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96EN9-1", "protein_name": "Required for excision 1-B domain-containing protein", "gene_name": "REX1BD", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MITETAAEPTVPAVPAAEEATEARGREEPAWPWKDAPIRTLVQRIHQLQAERAQGFRRLEEWLAPVQGLRAWGRGLRVPTCRRGHRQYLRSGPDYDFARYRSTVHGVTQAFAAASREVLAVEAELGGPRRQPLLAGHVRSLQELEQTRLGTVALLQLMETPELAGQEDAVRMQQLKMKVIKTMEAISEVLQDLRFDAESAE", "length": 201 }, "evidence": [ { "id": "RGD:1566239", "url": "https://alliancegenome.org/gene/RGD:1566239#orthology", "database": "AGR" }, { "id": "MGI:1913712", "url": "https://alliancegenome.org/gene/MGI:1913712#orthology", "database": "AGR" }, { "id": "HGNC:26098", "url": "https://alliancegenome.org/gene/HGNC:26098#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081031-40", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081031-40#orthology", "database": "AGR" }, { "id": "B8JL57", "url": "https://omabrowser.org/oma/group/B8JL57/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CYZ6-1", "protein_name": "Required for excision 1-B domain-containing protein", "gene_name": "Rex1bd", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLTAATEVLAAADGPGSAESAWAWRDAPIATLVQRIQQLQNERAQAFRRLDQAHRQYLLSGQHYDFPSYRSVVHEVTQAFAAASREVLAVEAELAGPRAQPVLARHVRSLQELEQTRLATVALLQVMGTPGVSEQDPEKLHQLKIKVIKTMEAIGEVLQELRFDAESAE", "length": 169 }, "evidence": [ { "id": "RGD:1566239", "url": "https://alliancegenome.org/gene/RGD:1566239#orthology", "database": "AGR" }, { "id": "MGI:1913712", "url": "https://alliancegenome.org/gene/MGI:1913712#orthology", "database": "AGR" }, { "id": "HGNC:26098", "url": "https://alliancegenome.org/gene/HGNC:26098#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081031-40", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081031-40#orthology", "database": "AGR" }, { "id": "B8JL57", "url": "https://omabrowser.org/oma/group/B8JL57/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JL64-1", "uniprot_ac": "B8JL64", "uniprot_id": "B8JL64_DANRE", "mass": { "chemical_mass": 38601.0, "monoisotopic_mass": 38601.0 }, "refseq": { "ac": "XP_688525", "name": "Krueppel-like factor 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688525" }, "gene_names": [ { "name": "klf5b", "type": "recommended", "evidence": [ { "id": "B8JL64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JL64" } ] }, { "name": "klf5b", "type": "synonym", "evidence": [ { "id": "XP_688525", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688525" } ] } ], "protein_names": [ { "name": "Krueppel-like factor 5", "type": "synonym", "evidence": [ { "id": "XP_688525", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688525" }, { "id": "B8JL64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JL64/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133184) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_688525.4. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_688525", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688525" } ] } ], "disease": [ { "disease_id": "DOID:10941", "recommended_name": { "id": "DOID:10941", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10941", "name": "intracranial aneurysm", "description": "" }, "synonyms": [ { "id": "DOID:10941", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:10941", "name": "brain aneurysm", "description": "" } ], "unlinked_id_list": [ "DOID:0060228" ], "evidence": [ { "id": "10941", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:10941" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JL64", "url": "https://www.uniprot.org/uniprotkb/B8JL64" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "klf5b", "url": "https://www.uniprot.org/uniprotkb/B8JL64", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080424-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080424-4", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000062106", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000062106", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd21579", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd21579", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "560043", "url": "https://www.ncbi.nlm.nih.gov/gene/560043", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:560043", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560043", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SLMHPTC", "url": "https://omabrowser.org/oma/group/SLMHPTC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JL64", "url": "https://www.orthodb.org/?gene=B8JL64", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23235:SF156", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23235:SF156", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_688525", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_688525", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JL64", "url": "https://www.uniprot.org/uniprotkb/B8JL64", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JL64-1", "url": "https://www.uniprot.org/uniprotkb/B8JL64-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-080424-4", "url": "https://zfin.org/ZDB-GENE-080424-4", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDGYLPPQFHALSDHKKYCQDNTFTMDQGTPYSINMNVFLPDVTYLRTGMCRTVRSVGPQIKTEPIHSSFNYSSCHGTVAPTMTHQEYTNLYTPAPETGSNVYIKHETPSIEFQDVPLFQLLNSDLEPNVPGGHSCTDSHNATCPPMSTYNSIHPASSHGTERSICNMASNGYSLPAQFGQHPQKRAAYLPPSPPNSEPGSPDRRKELIQNLSPPPSYAASMASKMACLTPGPALSVQTQQVPAQYNRRSNPDLDKRRIHHCDVPGCKKVYTKSSHLKAHLRTHTGEKPYKCSWEGCDWRFARSDELTRHFRKHTGAKPFQCSVCSRCFSRSDHLALHMKRHQN", "length": 344, "header": "tr|B8JL64-1|B8JL64_DANRE Isoform 1 of Krueppel-like factor 5 OS=Danio rerio OX=7955 GN=klf5b PE=4 SV=1 CANONICAL=B8JL64-1" }, "isoforms": [ { "isoform_ac": "B8JL64-1", "url": "https://www.uniprot.org/uniprotkb/B8JL64/entry#B8JL64-1", "sequence": { "sequence": "MDGYLPPQFHALSDHKKYCQDNTFTMDQGTPYSINMNVFLPDVTYLRTGMCRTVRSVGPQIKTEPIHSSFNYSSCHGTVAPTMTHQEYTNLYTPAPETGSNVYIKHETPSIEFQDVPLFQLLNSDLEPNVPGGHSCTDSHNATCPPMSTYNSIHPASSHGTERSICNMASNGYSLPAQFGQHPQKRAAYLPPSPPNSEPGSPDRRKELIQNLSPPPSYAASMASKMACLTPGPALSVQTQQVPAQYNRRSNPDLDKRRIHHCDVPGCKKVYTKSSHLKAHLRTHTGEKPYKCSWEGCDWRFARSDELTRHFRKHTGAKPFQCSVCSRCFSRSDHLALHMKRHQN", "length": 344, "header": "tr|B8JL64-1|B8JL64_DANRE Isoform 1 of Krueppel-like factor 5 OS=Danio rerio OX=7955 GN=klf5b PE=4 SV=1 CANONICAL=B8JL64-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:560043", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:560043", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9P800-1", "protein_name": "Krueppel-like factor 5", "gene_name": "klf5a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAATLLTMSAALAPGQDDFLSLLKPSLSDGFQQDSSLFCFEHKIPDSERGLSNDYSQAKLEMDKYLSPQPVVLPDLKKSRRESVSTMDQYFGDDHGSPYSINMNVYLPDIAYLRTGLCRAARHSVSNQVKTEPVTAPFSHPECPVSSSGPAPSALPDFTSIFNSNSTSGSGMDVVDDSAGVFVKQEMQGFDIPQDGPLFQLLNSELDVPDPTDPHAHSQMPTFHNLHLAAQQTAAKSYCGMAAHGYPLSHGHFVHPQDQAHSQLKMTYLPPSPPTSEPGSPDRQKELLHNLTPPPSYAATIASKMAGHAPSHPTPASTRPPTTTGSMPVRYNRRTNPDLEKRRIHHCDFPGCKKVYTKSSHLKAHLRTHTGEKPYRCTWEGCDWRFARSDELTRHFRKHTGAKPFQCAVCSRSFSRSDHLALHMKRHQN", "length": 429 }, "evidence": [ { "id": "HGNC:6349", "url": "https://alliancegenome.org/gene/HGNC:6349#orthology", "database": "AGR" }, { "id": "MGI:1338056", "url": "https://alliancegenome.org/gene/MGI:1338056#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1LSL7-1", "protein_name": "KLF transcription factor 5", "gene_name": "Klf5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MPTRVLTMSARLGPVPQPPAAQDEPVFAQLKPVLGAANPVRDAALFPGDDLKHAHHHPPAPPPAAGPRLPSEELVQTRCEMEKYLTPQLPPVPIISEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTQIKTEPVTIFSHQSESTAPPPPAPTQALPEFTSIFSSHQTTAPEVNNIFIKQELPIPDLHLSVPSQQGHLYQLLNTPDLDMPSSTNQTAVMDTLNVSMAGLNSHPSAVPQTSMKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPATLPVNSPNIQPVRYNRRSNPDLEKRRIHFCDYDGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCVVCNRSFSRSDHLALHMKRHQN", "length": 443 }, "evidence": [ { "id": "HGNC:6349", "url": "https://alliancegenome.org/gene/HGNC:6349#orthology", "database": "AGR" }, { "id": "MGI:1338056", "url": "https://alliancegenome.org/gene/MGI:1338056#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q13887-1", "protein_name": "Krueppel-like factor 5", "gene_name": "KLF5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MATRVLSMSARLGPVPQPPAPQDEPVFAQLKPVLGAANPARDAALFPGEELKHAHHRPQAQPAPAQAPQPAQPPATGPRLPPEDLVQTRCEMEKYLTPQLPPVPIIPEHKKYRRDSASVVDQFFTDTEGLPYSINMNVFLPDITHLRTGLYKSQRPCVTHIKTEPVAIFSHQSETTAPPPAPTQALPEFTSIFSSHQTAAPEVNNIFIKQELPTPDLHLSVPTQQGHLYQLLNTPDLDMPSSTNQTAAMDTLNVSMSAAMAGLNTHTSAVPQTAVKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPTTLPVNSQNIQPVRYNRRSNPDLEKRRIHYCDYPGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCGVCNRSFSRSDHLALHMKRHQN", "length": 457 }, "evidence": [ { "id": "HGNC:6349", "url": "https://alliancegenome.org/gene/HGNC:6349#orthology", "database": "AGR" }, { "id": "MGI:1338056", "url": "https://alliancegenome.org/gene/MGI:1338056#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080424-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080424-4#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VZN4-1", "protein_name": "Dendritic arbor reduction protein 1", "gene_name": "dar1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MHTDIIIGDQFAANNNYWVMQSPELDYRHELMGRLHKIEPADVELEVLAAAAAAANNNNNTSSNNNHSSNSSSNNSNGSQTPNGNNNSSLATGGHQHHQFHHHLHHHHSHQHHHQHHHLHQHHSHSLQSGESGASEAWPHLPAPSYASDVPHAQQQQLQPAGSPNSNSNGAYGCAPLYDGAPYEVALGYGGAVVASTGGATSSDKEYLYETKNKEALYADPLDDPYQRPVLWDDITTSIQNIDPENALMLSSSGSSNNNGSSNSSSNTGESATSQLPQVKMEAIDESLLETFSTPLLSPLEIKTEKQQRQQQHQHQQQQQQQQQQQQQHQQQHQQQYQQQHYQQHYQQQHLYQHHPSLALPGLPPAVDVVELQLQQQHQQQQHLQHNNSSSSSPKLATPGDNSGNTSSYQQQYASQLVSGSGGGYLNGSSSNSYGYSWHSSQSFHTKYQIHPPSAAASATASATATPTAQLGAQQQQQQQQQQQLQQLCPPAAPSTPSTSSSSISSSSASSASRHMFVPPLTPPSSDPGSPGSSMVAAAAAAAAQRRTTPPPPYQQGHVMGLINPPPTLQLLGGAATGSNNSCTTTLTTLTPASAIQQQQQQPQQQQVPQQQPPPTPRSSGGGRRGRHSHHQPGTAAHIASLMSVRTVRYNRRNNPELEKRRIHHCDFVGCSKVYTKSSHLKAHQRIHTGEKPYTCQWPECEWRFARSDELTRHYRKHTGAKPFKCIVCERSFARSDHLALHMKRHLPKNK", "length": 751 }, "evidence": [ { "id": "HGNC:6349", "url": "https://alliancegenome.org/gene/HGNC:6349#orthology", "database": "AGR" }, { "id": "MGI:1338056", "url": "https://alliancegenome.org/gene/MGI:1338056#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z0Z7-1", "protein_name": "Krueppel-like factor 5", "gene_name": "Klf5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MPTRVLTMSARLGPLPQPPAAQDEPVFAQLKPVLGAANPARDAALFSGDDLKHAHHHPPAPPPAAGPRLPSEELVQTRCEMEKYLTPQLPPVPIISEHKKYRRDSASVVDQFFTDTEGIPYSINMNVFLPDITHLRTGLYKSQRPCVTQIKTEPVTIFSHQSESTAPPPPPAPTQALPEFTSIFSSHQTTAPPQEVNNIFIKQELPIPDLHLSVPSQQGHLYQLLNTPDLDMPSSTNQTAVMDTLNVSMAGLNPHPSAVPQTSMKQFQGMPPCTYTMPSQFLPQQATYFPPSPPSSEPGSPDRQAEMLQNLTPPPSYAATIASKLAIHNPNLPATLPVNSPTLPPVRYNRRSNPDLEKRRIHFCDYNGCTKVYTKSSHLKAHLRTHTGEKPYKCTWEGCDWRFARSDELTRHYRKHTGAKPFQCMVCQRSFSRSDHLALHMKRHQN", "length": 446 }, "evidence": [ { "id": "HGNC:6349", "url": "https://alliancegenome.org/gene/HGNC:6349#orthology", "database": "AGR" }, { "id": "MGI:1338056", "url": "https://alliancegenome.org/gene/MGI:1338056#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-080424-4", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080424-4#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B8JL64", "url": "https://www.uniprot.org/uniprotkb/B8JL64" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "B8JL64", "url": "https://www.uniprot.org/uniprotkb/B8JL64" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "B8JL64", "url": "https://www.uniprot.org/uniprotkb/B8JL64" } ], "pmid": "" }, { "name": "RNA polymerase II cis-regulatory region sequence-specific DNA binding", "id": "GO:0000978", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000978", "evidence": [ { "database": "UniProtKB", "id": "B8JL64", "url": "https://www.uniprot.org/uniprotkb/B8JL64" } ], "pmid": "" }, { "name": "DNA-binding transcription factor activity, RNA polymerase II-specific", "id": "GO:0000981", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000981", "evidence": [ { "database": "UniProtKB", "id": "B8JL64", "url": "https://www.uniprot.org/uniprotkb/B8JL64" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 211, "end_pos": 213, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8JL64", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JL64" }, { "id": "PS50157", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50157" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 260, "end_pos": 289, "start_aa": "His", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 211, "end_pos": 213 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B8JLB2-1", "uniprot_ac": "B8JLB2", "uniprot_id": "B8JLB2_DANRE", "mass": { "chemical_mass": 22621.0, "monoisotopic_mass": 22621.0 }, "refseq": { "ac": "NP_001093453", "name": "ADP-ribosylation factor-like protein 14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093453" }, "gene_names": [ { "name": "arl14", "type": "recommended", "evidence": [ { "id": "B8JLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ] }, { "name": "arl14", "type": "synonym", "evidence": [ { "id": "NP_001093453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093453" } ] }, { "name": "si:dkey-119f1.4", "type": "synonym", "evidence": [ { "id": "NP_001093453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093453" }, { "id": "B8JLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ] } ], "protein_names": [ { "name": "ADP-ribosylation factor-like protein 14", "type": "recommended", "evidence": [ { "id": "B8JLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLB2/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor 7", "type": "synonym", "evidence": [ { "id": "B8JLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLB2/entry#names_and_taxonomy" } ] }, { "name": "ADP-ribosylation factor-like protein 14", "type": "synonym", "evidence": [ { "id": "NP_001093453", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093453" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript is intronless :: GFIL01001529.1, SRR26395017.920444.1 [ECO:0000345] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000002.1 and AL918790.1. On Jul 26, 2007 this sequence version replaced XP_684949.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001093453", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093453" } ] }, { "annotation": "GTPase that recruits MYO1E to MHC class II-containing vesicles via the effector protein ARL14EP and hence controls the movement of these vesicles along the actin cytoskeleton in dendritic cells.", "evidence": [ { "database": "UniProtKB", "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2#function" }, { "database": "UniProtKB", "id": "ARBA00054077", "url": "https://www.uniprot.org/uniprotkb/ARBA00054077#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "arl14", "url": "https://www.uniprot.org/uniprotkb/B8JLB2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-288", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-288", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000063223", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000063223", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "556921", "url": "https://www.ncbi.nlm.nih.gov/gene/556921", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR005225", "url": "https://www.ebi.ac.uk/interpro/entry/IPR005225", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006689", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006689", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR024156", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024156", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556921", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556921", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EYYCENT", "url": "https://omabrowser.org/oma/group/EYYCENT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JLB2", "url": "https://www.orthodb.org/?gene=B8JLB2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11711", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11711", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00025", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00025", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001093453", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001093453", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JLB2-1", "url": "https://www.uniprot.org/uniprotkb/B8JLB2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070705-288", "url": "https://zfin.org/ZDB-GENE-070705-288", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGHSGSRHKPEARILLLGLDNAGKSTLLYKLKYDENFHTVPTIGFNVEMIEAKKNRDKISLTVWDVGGQAKMRAFWRNFYQDTAGIVFVVDSSDVKRLDEAKGVLEQSLRSEHLRGLPVVVLANKQDIVGAATVTEITEQFNLRKSCSDRDWFIQPCSALTGAGLVDGFRRMAHLVKMTPDDNNIKETVKYIRAKSVIQKK", "length": 201, "header": "tr|B8JLB2-1|B8JLB2_DANRE Isoform 1 of ADP-ribosylation factor-like protein 14 OS=Danio rerio OX=7955 GN=arl14 PE=3 SV=1 CANONICAL=B8JLB2-1" }, "isoforms": [ { "isoform_ac": "B8JLB2-1", "url": "https://www.uniprot.org/uniprotkb/B8JLB2/entry#B8JLB2-1", "sequence": { "sequence": "MGHSGSRHKPEARILLLGLDNAGKSTLLYKLKYDENFHTVPTIGFNVEMIEAKKNRDKISLTVWDVGGQAKMRAFWRNFYQDTAGIVFVVDSSDVKRLDEAKGVLEQSLRSEHLRGLPVVVLANKQDIVGAATVTEITEQFNLRKSCSDRDWFIQPCSALTGAGLVDGFRRMAHLVKMTPDDNNIKETVKYIRAKSVIQKK", "length": 201, "header": "tr|B8JLB2-1|B8JLB2_DANRE Isoform 1 of ADP-ribosylation factor-like protein 14 OS=Danio rerio OX=7955 GN=arl14 PE=3 SV=1 CANONICAL=B8JLB2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene duplication of C-type natriuretic peptide-4 (CNP4) in teleost lineage elicits subfunctionalization of ancestral CNP.", "journal": "Cell Tissue Res.", "date": "2022", "authors": "Katayama Yukitoshi, Saito Ami, Ogoshi Maho, Tsuneoka Yousuke, Mukuda Takao, Azuma Morio, Kusakabe Makoto, Takei Yoshio, Tsukada Takehiro", "evidence": [ { "database": "UniProtKB", "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ], "reference": [ { "type": "PubMed", "id": "35171324", "url": "https://glygen.org/publication/PubMed/35171324" } ] } ], "pathway": [ { "id": "dre:556921", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556921", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "M0R6N0-1", "protein_name": "ADP-ribosylation factor-like protein 14", "gene_name": "Arl14", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGLLSSKNPKDKQAHILLLGLDSAGKSTLLYRLKFAETLATIPTIGFNVEMVQLQSGLALTVWDIGGQEKMRTVWDCYCENAHGLVYVVDCSEGQKRLEDSRKEFKHILKNEHIKNTPVVILANKQDLPGALSAEDITRMFKVKKLCSDRNWYVQPCCAVTGEGLDDGFRKLTEFVKSHLKTRETLAFFKQK", "length": 192 }, "evidence": [ { "id": "MGI:1918869", "url": "https://alliancegenome.org/gene/MGI:1918869#orthology", "database": "AGR" }, { "id": "HGNC:22974", "url": "https://alliancegenome.org/gene/HGNC:22974#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3SXC5-1", "protein_name": "ADP-ribosylation factor-like protein 14", "gene_name": "Arl14", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGLLNSKNPQSKQAHILLLGLDSAGKSTLLYRLKFAETLATIPTIGFNVEMVQLQSSLTLTVWDVGGQEKMRTVWDCYCENAQGLMYVVDCSEGKKRLEDSRKEFKHILKNEHIKNTPVVILANKQDLPGALSAEDITRMFKVKKLCSNRNWYVQPCCAVTGEGLDDGFRKLTEFLKSYRRTRETLAIFKQK", "length": 192 }, "evidence": [ { "id": "MGI:1918869", "url": "https://alliancegenome.org/gene/MGI:1918869#orthology", "database": "AGR" }, { "id": "HGNC:22974", "url": "https://alliancegenome.org/gene/HGNC:22974#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-288", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-288#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8N4G2-1", "protein_name": "ADP-ribosylation factor-like protein 14", "gene_name": "ARL14", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGSLGSKNPQTKQAQVLLLGLDSAGKSTLLYKLKLAKDITTIPTIGFNVEMIELERNLSLTVWDVGGQEKMRTVWGCYCENTDGLVYVVDSTDKQRLEESQRQFEHILKNEHIKNVPVVLLANKQDMPGALTAEDITRMFKVKKLCSDRNWYVQPCCALTGEGLAQGFRKLTGFVKSHMKSRGDTLAFFKQN", "length": 192 }, "evidence": [ { "id": "MGI:1918869", "url": "https://alliancegenome.org/gene/MGI:1918869#orthology", "database": "AGR" }, { "id": "HGNC:22974", "url": "https://alliancegenome.org/gene/HGNC:22974#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070705-288", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-288#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "GTPase activity", "id": "GO:0003924", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003924", "evidence": [ { "database": "UniProtKB", "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ], "pmid": "" }, { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ], "pmid": "" }, { "name": "metal ion binding", "id": "GO:0046872", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0046872", "evidence": [ { "database": "UniProtKB", "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ], "pmid": "" }, { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "intracellular protein transport", "id": "GO:0006886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006886", "evidence": [ { "database": "UniProtKB", "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ], "pmid": "" }, { "name": "vesicle-mediated transport", "id": "GO:0016192", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016192", "evidence": [ { "database": "UniProtKB", "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ], "pmid": "" }, { "name": "establishment of cell polarity", "id": "GO:0030010", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030010", "evidence": [ { "database": "UniProtKB", "id": "B8JLB2", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [ { "evidence": [ { "id": "B8JLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLB2#function" }, { "id": "B8JLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 25, "amino_acid": "Ser", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 25, "end_pos": 25, "start_aa": "Ser", "end_aa": "Ser", "glycosite_overlap": "" }, { "evidence": [ { "id": "B8JLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLB2#function" }, { "id": "B8JLB2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLB2" }, { "id": "PIRSR606689-2", "database": "PIR Site Rule", "url": "https://proteininformationresource.org/cgi-bin/pirrule?id=PIRSR606689-2" } ], "binding_site_uniprot": 42, "amino_acid": "Thr", "chebi_lig_id": "CHEBI_18420", "ligand": "Mg(2+)", "ligand_label": "", "uniprotkb_ligand_comment": "", "eco_id": "ECO_0000256", "start_pos": 42, "end_pos": 42, "start_aa": "Thr", "end_aa": "Thr", "glycosite_overlap": "" } ], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JLD0-1", "uniprot_ac": "B8JLD0", "uniprot_id": "B8JLD0_DANRE", "mass": { "chemical_mass": 24083.0, "monoisotopic_mass": 24083.0 }, "refseq": { "ac": "NP_001373568", "name": "uncharacterized protein LOC571662", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373568" }, "gene_names": [ { "name": "sertad2a", "type": "recommended", "evidence": [ { "id": "B8JLD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLD0" } ] }, { "name": "im:7152879", "type": "synonym", "evidence": [ { "id": "NP_001373568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373568" }, { "id": "B8JLD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLD0" } ] }, { "name": "sertad2a", "type": "synonym", "evidence": [ { "id": "NP_001373568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373568" } ] }, { "name": "si:ch73-131e21.6", "type": "synonym", "evidence": [ { "id": "NP_001373568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373568" }, { "id": "B8JLD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLD0" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC571662", "type": "synonym", "evidence": [ { "id": "B8JLD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLD0/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC571662", "type": "synonym", "evidence": [ { "id": "NP_001373568", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373568" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQQ01038458.1, EH590005.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505373, SAMEA4476767 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Aug 29, 2020 this sequence version replaced XP_003197790.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001373568", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373568" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JLD0", "url": "https://www.uniprot.org/uniprotkb/B8JLD0" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sertad2a", "url": "https://www.uniprot.org/uniprotkb/B8JLD0", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050309-236", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050309-236", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "571662", "url": "https://www.ncbi.nlm.nih.gov/gene/571662", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052262", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052262", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:571662", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571662", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "B8JLD0", "url": "https://www.orthodb.org/?gene=B8JLD0", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16277:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16277:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001373568", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373568", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JLD0", "url": "https://www.uniprot.org/uniprotkb/B8JLD0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JLD0-1", "url": "https://www.uniprot.org/uniprotkb/B8JLD0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050309-236", "url": "https://zfin.org/ZDB-GENE-050309-236", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLSKGLKRKLEDEDEPEVSNNGSSLDESESESSSGYRLQRQTVLNLSLLKLHSVPGHSEPRLSRRVLISNTLRHIRDELRVEGGASVRLQPSITKDAFSSALADIEDLCPTVGITALFSTADVSSSSESVHSDESRSVDSDLSEMRSKSLSDSTHPVLGHTSSLIADFSLDDFLFTEIDNFLLDSKTGFGGAGIGQSALQTNQTFKLDLSELDHIMEVLVGS", "length": 222, "header": "tr|B8JLD0-1|B8JLD0_DANRE Isoform 1 of Uncharacterized protein LOC571662 OS=Danio rerio OX=7955 GN=sertad2a PE=4 SV=1 CANONICAL=B8JLD0-1" }, "isoforms": [ { "isoform_ac": "B8JLD0-1", "url": "https://www.uniprot.org/uniprotkb/B8JLD0/entry#B8JLD0-1", "sequence": { "sequence": "MLSKGLKRKLEDEDEPEVSNNGSSLDESESESSSGYRLQRQTVLNLSLLKLHSVPGHSEPRLSRRVLISNTLRHIRDELRVEGGASVRLQPSITKDAFSSALADIEDLCPTVGITALFSTADVSSSSESVHSDESRSVDSDLSEMRSKSLSDSTHPVLGHTSSLIADFSLDDFLFTEIDNFLLDSKTGFGGAGIGQSALQTNQTFKLDLSELDHIMEVLVGS", "length": 222, "header": "tr|B8JLD0-1|B8JLD0_DANRE Isoform 1 of Uncharacterized protein LOC571662 OS=Danio rerio OX=7955 GN=sertad2a PE=4 SV=1 CANONICAL=B8JLD0-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JLD0", "url": "https://www.uniprot.org/uniprotkb/B8JLD0" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Galectins in channel catfish, Ictalurus punctatus: Characterization and expression profiling in mucosal tissues.", "journal": "Fish Shellfish Immunol.", "date": "2016", "authors": "Zhou Shun, Zhao Honggang, Thongda Wilawan, Zhang Dongdong, Su Baofeng, Yu Dan, Peatman Eric, Li Chao", "evidence": [ { "database": "UniProtKB", "id": "B8JLD0", "url": "https://www.uniprot.org/uniprotkb/B8JLD0" } ], "reference": [ { "type": "PubMed", "id": "26767746", "url": "https://glygen.org/publication/PubMed/26767746" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8JLD0", "url": "https://www.uniprot.org/uniprotkb/B8JLD0" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:571662", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:571662", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A0D3-1", "protein_name": "SERTA domain containing 2", "gene_name": "Sertad2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSPLAFIVTRFLGPIQPSTKTPFWILSWRRMTGRKQSGVGGSGVASSVMSGAGLHPATRVLLPNTTLALGCALLYMLGKGGKRKFDEHEDGLEGKVVFPSDAPSRVSYTLQRQTIFNISLMKLYNHRPLTEPSLQKTVLINNMLRRIQEELKQEGSLRPTFTPTSQPSDSLSDSYREAPPAFTPLASPPAHPCDLGSTTPLEACLTPASLLEGDDDTFCTLQAVHPAAPTRLSSPALSAEKDSFSSALDEIEELCPTSTSTEAAAAAAPEGSKGTSSETSVQKPEGPQEGRTDDSRFMDSLPGNFEITTSTGFLTDLTLDDILFADIDTSMYDFDPCTSASGTASKMAPVSADDLLKTLAPYSNQPVAPSQPFKMDLTELDHIMEVLVGS", "length": 390 }, "evidence": [ { "id": "HGNC:30784", "url": "https://alliancegenome.org/gene/HGNC:30784#orthology", "database": "AGR" }, { "id": "MGI:1931026", "url": "https://alliancegenome.org/gene/MGI:1931026#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q14140-1", "protein_name": "SERTA domain-containing protein 2", "gene_name": "SERTAD2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLGKGGKRKFDEHEDGLEGKIVSPCDGPSKVSYTLQRQTIFNISLMKLYNHRPLTEPSLQKTVLINNMLRRIQEELKQEGSLRPMFTPSSQPTTEPSDSYREAPPAFSHLASPSSHPCDLGSTTPLEACLTPASLLEDDDDTFCTSQAMQPTAPTKLSPPALLPEKDSFSSALDEIEELCPTSTSTEAATAATDSVKGTSSEAGTQKLDGPQESRADDSKLMDSLPGNFEITTSTGFLTDLTLDDILFADIDTSMYDFDPCTSSSGTASKMAPVSADDLLKTLAPYSSQPVTPSQPFKMDLTELDHIMEVLVGS", "length": 314 }, "evidence": [ { "id": "HGNC:30784", "url": "https://alliancegenome.org/gene/HGNC:30784#orthology", "database": "AGR" }, { "id": "MGI:1931026", "url": "https://alliancegenome.org/gene/MGI:1931026#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050309-236", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050309-236#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9JJG5-1", "protein_name": "SERTA domain-containing protein 2", "gene_name": "Sertad2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLGKGGKRKFDEHEDGLEGKIVSPSDGPSRVSYTLQRQTIFNISLMKLYNHRPLTEPSLQKTVLINNMLRRIQEELKQEGSLRPAFTPSSQPSNSLSDSYQEAPPPAPHPCDLGSTTPLEACLTPASLLEDDNDDTFCTLQAVHPAAPTRLSSAALPAEKDSFSSALDEIEELCPTSTSTEAAHTAAPEGPKGTSSESSVQKPEGPEEGRTDDSRFMDSLPGNFEITTSTGFLTDLTLDDILFADIDTSMYDFDPCTSASGTASKMAPVSADDLLKTLAPYSNQPVAPSQPFKMDLTELDHIMEVLVGS", "length": 309 }, "evidence": [ { "id": "HGNC:30784", "url": "https://alliancegenome.org/gene/HGNC:30784#orthology", "database": "AGR" }, { "id": "MGI:1931026", "url": "https://alliancegenome.org/gene/MGI:1931026#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050309-236", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050309-236#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VEX7-1", "protein_name": "Taranis, isoform A", "gene_name": "tara", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKMWTESNVNSAMGLQATAATKRKHELTFDSKDANTTYTGNCAPPPVKANKWAISNNNYLESLEEQQQQQQSPSEPAVESNNNHIVLEASMDALKPTEPSISNGHEVTTAVAAMKSQAEVPLPPTASAAIPEDSIARLEVVTSAVPCEPWTSNGPTTPSAVAGPAASAEPVDCISKLQAVAVPSDPWGSIATRSTLATTLLSADELDDDDDDFEDDYEEEESIIPTYCPMRYHPFVPHPHPHSHQLPSHPHQQQPQQLSQQQPHPQQQQLAQQQQQHPQQQRSYAPGYGSRQPNYYSEPFPQQNCSRTGGPQHMTQSPPTPQQARGFAPPQWATAGSSPANPSSGAQQFYEPTNGGAYAPPAAPQQTIRCAENGKSYLDLGCSSGASGNAGGSPISPPPSSAPVVPFAGLPLHGLPLKRCCDGRPGGWCSANRSCYKDTRLKIRNLSMFKLSRFRQVSEQSLYRSVLICNTLKRIDREIEAEAKELHQAAQQHHQQAAAAAAAAAAAAAQAAQYHPAYQQQQQQQQSPPAPLHPHTQQQMDYAPVLNCARLANMDHYQQLSFQPQHQQQQQPSQPHSYHERLDSQPAYRGAAAGAGSFATQPSNCDTSAGASSSNTSGNSNNSSATAASSNSSLHPYDHYPFRESQSGRATPFPACPTTTAAAAAASAAAAASSGGAATTLSSNISSSPASSSTSSNTTSSTVISSSSGNTVSSNGTTPVAPTASSSNCDTSDSGYADDDSTRSINWSSVLSLSSQSALDPLNNNDLFSILPSAATPTAVPVSVPASSSSSSSGSTLAFSGSFTTVQASGGSSSSCGSSSTTATFTTLSTISSATHSLTSSYVSSISSNVSAGANTWEYGFLDMEFGLGSEFTELVPSCKLSSEDLFKSGLGGQVVTASRLHDNELEHPAHIMVGS", "length": 916 }, "evidence": [ { "id": "HGNC:30784", "url": "https://alliancegenome.org/gene/HGNC:30784#orthology", "database": "AGR" }, { "id": "MGI:1931026", "url": "https://alliancegenome.org/gene/MGI:1931026#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "B8JLD0", "url": "https://www.uniprot.org/uniprotkb/B8JLD0" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B8JLD0", "url": "https://www.uniprot.org/uniprotkb/B8JLD0" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B8JLD0", "url": "https://www.uniprot.org/uniprotkb/B8JLD0" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 21, "end_pos": 23, "annotation": "n_glycosylation_sequon" }, { "start_pos": 45, "end_pos": 47, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8JLD0", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLD0" }, { "id": "PS51053", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51053" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SERTA", "eco_id": "ECO_0000259", "start_pos": 36, "end_pos": 83, "start_aa": "Tyr", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 202, "end_pos": 204 }, { "start_pos": 21, "end_pos": 23 }, { "start_pos": 45, "end_pos": 47 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JLG8-1", "uniprot_ac": "B8JLG8", "uniprot_id": "B8JLG8_DANRE", "mass": { "chemical_mass": 57394.0, "monoisotopic_mass": 57394.0 }, "refseq": { "ac": "XP_692664", "name": "nucleotidyltransferase MB21D2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692664" }, "gene_names": [ { "name": "mb21d2", "type": "recommended", "evidence": [ { "id": "B8JLG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLG8" } ] }, { "name": "mb21d2", "type": "synonym", "evidence": [ { "id": "XP_692664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692664" } ] } ], "protein_names": [ { "name": "Nucleotidyltransferase MB21D2", "type": "synonym", "evidence": [ { "id": "B8JLG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLG8/entry#names_and_taxonomy" } ] }, { "name": "nucleotidyltransferase MB21D2", "type": "synonym", "evidence": [ { "id": "XP_692664", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692664" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 15, 2007 this sequence version replaced XP_692664.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_692664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692664" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JLG8", "url": "https://www.uniprot.org/uniprotkb/B8JLG8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mb21d2", "url": "https://www.uniprot.org/uniprotkb/B8JLG8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-150", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-150", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077690", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077690", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "564222", "url": "https://www.ncbi.nlm.nih.gov/gene/564222", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR024810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR024810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046903", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046903", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046906", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046906", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564222", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564222", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MFHARKL", "url": "https://omabrowser.org/oma/group/MFHARKL/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JLG8", "url": "https://www.orthodb.org/?gene=B8JLG8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR10656:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10656:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03281", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03281", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF20266", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_692664", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_692664", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JLG8", "url": "https://www.uniprot.org/uniprotkb/B8JLG8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JLG8-1", "url": "https://www.uniprot.org/uniprotkb/B8JLG8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-150", "url": "https://zfin.org/ZDB-GENE-081104-150", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAAPAPSSRTGSVSSSLGNSPTATPGPGGLNNGHKLWCCHELDFRSGVKIEELNRLIHEFSKQDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDMDVDELGVYTRGSDYDMAFTLLVPALKLHDRNQPVTLDMRHSALGHSWLSLRLFDEGTINRWRDCCTLTDHLNGTTNYFFSPTMVADWFQEAVGLVLAELQRKPQRGTPRVERVERHSTLLSMVLGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLLPACSASGCRENEWRLSFARSEVQLKKCISPGLMQAYQACKAIVVKLLGQPTAISPYYLRSMMLWACDRLPATYLSQDDYAAYFLLGLIDDLQHCLVNKACPNYFIPQCNMLEHLCDETAMFHARKLALVRSDPAEHLRSIIEQAKASNRLTQEMQRCGSSSGLPSPLADSSLADHQQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 510, "header": "tr|B8JLG8-1|B8JLG8_DANRE Isoform 1 of Nucleotidyltransferase MB21D2 OS=Danio rerio OX=7955 GN=mb21d2 PE=3 SV=1 CANONICAL=B8JLG8-1" }, "isoforms": [ { "isoform_ac": "B8JLG8-1", "url": "https://www.uniprot.org/uniprotkb/B8JLG8/entry#B8JLG8-1", "sequence": { "sequence": "MAAPAPSSRTGSVSSSLGNSPTATPGPGGLNNGHKLWCCHELDFRSGVKIEELNRLIHEFSKQDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDMDVDELGVYTRGSDYDMAFTLLVPALKLHDRNQPVTLDMRHSALGHSWLSLRLFDEGTINRWRDCCTLTDHLNGTTNYFFSPTMVADWFQEAVGLVLAELQRKPQRGTPRVERVERHSTLLSMVLGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLLPACSASGCRENEWRLSFARSEVQLKKCISPGLMQAYQACKAIVVKLLGQPTAISPYYLRSMMLWACDRLPATYLSQDDYAAYFLLGLIDDLQHCLVNKACPNYFIPQCNMLEHLCDETAMFHARKLALVRSDPAEHLRSIIEQAKASNRLTQEMQRCGSSSGLPSPLADSSLADHQQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 510, "header": "tr|B8JLG8-1|B8JLG8_DANRE Isoform 1 of Nucleotidyltransferase MB21D2 OS=Danio rerio OX=7955 GN=mb21d2 PE=3 SV=1 CANONICAL=B8JLG8-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 24, "start_aa": "Thr", "end_pos": 24, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr24", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:564222", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564222", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4ACS3-1", "protein_name": "Nucleotidyltransferase MB21D2", "gene_name": "Mb21d2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKMAAPTASKAASMGCNNKPAFPELDFRSGARVEELNKLIQEFTRHDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIADHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISGSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPVSYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLKLQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 491 }, "evidence": [ { "id": "MGI:1917028", "url": "https://alliancegenome.org/gene/MGI:1917028#orthology", "database": "AGR" }, { "id": "HGNC:30438", "url": "https://alliancegenome.org/gene/HGNC:30438#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8C525-1", "protein_name": "Nucleotidyltransferase MB21D2", "gene_name": "Mb21d2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLQTPMTGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKGCCTIADHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISGSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPASYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLKLQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 428 }, "evidence": [ { "id": "MGI:1917028", "url": "https://alliancegenome.org/gene/MGI:1917028#orthology", "database": "AGR" }, { "id": "HGNC:30438", "url": "https://alliancegenome.org/gene/HGNC:30438#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-150", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-150#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8IYB1-1", "protein_name": "Nucleotidyltransferase MB21D2", "gene_name": "MB21D2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKMAAPTANKAASLGCNNKPAFPELDFRSGARVEELNKLIQEFTKHDQREYDDQRALEIHTAKDFIFSMLGMVQKLDQKLPVANEYLLLSGGVREGVVDLDLDELNVYARGTDYDMDFTLLVPALKLHDRNQPVTLDMRHSALCHSWLSLRLFDEGTISKWKDCCTIVDHINGATNYFFSPTKVADWFYDSISIVLSEIQKKPQRGMPKVEKVEKNGTIISIILGVGSSRMLYDIVPVVSFKGWPAVAQSWLMENHFWDGKITEEEVISGFYLVPACSYKGKKDNEWRLSFARSEVQLKKCISSSLMQAYQACKAIIIKLLSRPKAISPYHLRSMMLWACDRLPANYLAQEDYAAHFLLGLIDDLQHCLVNKMCPNYFIPQCNMLEHLSEETVMLHARKLSSVRSDPAEHLRTAIEHVKAANRLTLELQRRGSTTSIPSPQSDGGDPNQPDDRLAKKLQQLVTENPGKSISVFINPDDVTRPHFRIDDKFF", "length": 491 }, "evidence": [ { "id": "MGI:1917028", "url": "https://alliancegenome.org/gene/MGI:1917028#orthology", "database": "AGR" }, { "id": "HGNC:30438", "url": "https://alliancegenome.org/gene/HGNC:30438#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-150", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-150#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 189, "end_pos": 191, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8JLG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLG8" }, { "id": "PF20266", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF20266" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like HhH/H2TH-like", "eco_id": "ECO_0000259", "start_pos": 342, "end_pos": 417, "start_aa": "Thr", "end_aa": "Leu", "glycosite_overlap": "" }, { "evidence": [ { "id": "B8JLG8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLG8" }, { "id": "PF03281", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03281" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Mab-21-like nucleotidyltransferase", "eco_id": "ECO_0000259", "start_pos": 177, "end_pos": 315, "start_aa": "Arg", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 24 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 189, "end_pos": 191 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": 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"total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B8JLK1-1", "uniprot_ac": "B8JLK1", "uniprot_id": "B8JLK1_DANRE", "mass": { "chemical_mass": 13112.0, "monoisotopic_mass": 13112.0 }, "refseq": { "ac": "NP_001138265", "name": "microtubule nucleation factor SSNA1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138265" }, "gene_names": [ { "name": "ssna1", "type": "recommended", "evidence": [ { "id": "B8JLK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLK1" } ] }, { "name": "si:ch73-203i15.4", "type": "synonym", "evidence": [ { "id": "NP_001138265", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138265" }, { "id": "B8JLK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLK1" } ] }, { "name": "ssna1", "type": "synonym", "evidence": [ { "id": "NP_001138265", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138265" } ] } ], "protein_names": [ { "name": "Microtubule nucleation factor SSNA1", "type": "synonym", "evidence": [ { "id": "B8JLK1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLK1/entry#names_and_taxonomy" } ] }, { "name": "microtubule nucleation factor SSNA1", "type": "synonym", "evidence": [ { "id": "NP_001138265", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138265" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH536039.1, EH571544.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476728, SAMEA4476733 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000005.1. On Jan 25, 2009 this sequence version replaced XP_689621.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001138265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138265" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JLK1", "url": "https://www.uniprot.org/uniprotkb/B8JLK1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ssna1", "url": "https://www.uniprot.org/uniprotkb/B8JLK1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-255", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-255", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000101300", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000101300", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "561124", "url": "https://www.ncbi.nlm.nih.gov/gene/561124", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR033362", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033362", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561124", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561124", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETKNEYD", "url": "https://omabrowser.org/oma/group/ETKNEYD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JLK1", "url": "https://www.orthodb.org/?gene=B8JLK1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28661", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28661", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28661:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28661:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27720", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27720", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-380320", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-380320", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001138265", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138265", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JLK1", "url": "https://www.uniprot.org/uniprotkb/B8JLK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JLK1-1", "url": "https://www.uniprot.org/uniprotkb/B8JLK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-255", "url": "https://zfin.org/ZDB-GENE-081104-255", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTQQGAALQTYNNELVKCIEELCSKREDLNRLIQQEEAEKARLQHDIRVLTEKLSRVNESLAHRLSARAEFDRTIAETEAAYMKILESSQTLLSVLKKEAGNLTKATEPRSSKDH", "length": 115, "header": "tr|B8JLK1-1|B8JLK1_DANRE Isoform 1 of Microtubule nucleation factor SSNA1 OS=Danio rerio OX=7955 GN=ssna1 PE=1 SV=1 CANONICAL=B8JLK1-1" }, "isoforms": [ { "isoform_ac": "B8JLK1-1", "url": "https://www.uniprot.org/uniprotkb/B8JLK1/entry#B8JLK1-1", "sequence": { "sequence": "MTQQGAALQTYNNELVKCIEELCSKREDLNRLIQQEEAEKARLQHDIRVLTEKLSRVNESLAHRLSARAEFDRTIAETEAAYMKILESSQTLLSVLKKEAGNLTKATEPRSSKDH", "length": 115, "header": "tr|B8JLK1-1|B8JLK1_DANRE Isoform 1 of Microtubule nucleation factor SSNA1 OS=Danio rerio OX=7955 GN=ssna1 PE=1 SV=1 CANONICAL=B8JLK1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8JLK1", "url": "https://www.uniprot.org/uniprotkb/B8JLK1" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:561124", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561124", "resource": "KEGG Pathway" }, { "id": "R-DRE-380320", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-380320", "resource": "Reactome", "description": "Recruitment of NuMA to mitotic centrosomes" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AHZ7-1", "protein_name": "SS nuclear autoantigen 1", "gene_name": "SSNA1", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MTQQGAALQNYNNELVKCIEELCQKREELCRQIQQEEDEKQRLQNEVRQLTEKLARVNENLARKIASRNEFDRTIAETEAAYLKILESSQTLLSVLKREAGNLTKATASEQKSSGGKDS", "length": 119 }, "evidence": [ { "id": "B8JLK1", "url": "https://omabrowser.org/oma/group/B8JLK1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "B2RZ20-1", "protein_name": "SS nuclear autoantigen 1", "gene_name": "Ssna1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTQQGAALQNYNNELVKCIEELCQKREELCRQIQQEEDEKQRLQNEVRQLTEKLARVNENLARKIASRNEFDRTIAETEAAYLKILESSQTLLSVLKREAGNLTKATASDQKSSGGKDS", "length": 119 }, "evidence": [ { "id": "RGD:1310259", "url": "https://alliancegenome.org/gene/RGD:1310259#orthology", "database": "AGR" }, { "id": "MGI:1915725", "url": "https://alliancegenome.org/gene/MGI:1915725#orthology", "database": "AGR" }, { "id": "HGNC:11321", "url": "https://alliancegenome.org/gene/HGNC:11321#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-255", "url": 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"https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-255#orthology", "database": "AGR" }, { "id": "B8JLK1", "url": "https://omabrowser.org/oma/group/B8JLK1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q5E9C3-1", "protein_name": "Microtubule nucleation factor SSNA1", "gene_name": "SSNA1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MTQQGAALQNYNNELVKCIEELCQKREELCRQIQQEEEEKQRLQNEVRQLTEKLARVNENLARKIASRNEFDRTIAETEAAYLKILESSQTLLSVLKREAGNLTKATASEQKSSGGKES", "length": 119 }, "evidence": [ { "id": "B8JLK1", "url": "https://omabrowser.org/oma/group/B8JLK1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9JJ94-1", "protein_name": "Microtubule nucleation factor SSNA1", "gene_name": "Ssna1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": 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"url": "https://www.uniprot.org/uniprotkb/B8JLW4" } ] }, { "name": "c18h3orf33", "type": "synonym", "evidence": [ { "id": "NP_001138268", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138268" } ] }, { "name": "c3orf33", "type": "synonym", "evidence": [ { "id": "NP_001138268", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138268" }, { "id": "B8JLW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLW4" } ] }, { "name": "c6orf33", "type": "synonym", "evidence": [ { "id": "NP_001138268", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138268" }, { "id": "B8JLW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLW4" } ] }, { "name": "miso1", "type": "synonym", "evidence": [ { "id": "NP_001138268", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138268" } ] } ], "protein_names": [ { "name": "Protein C3orf33 homolog", "type": "synonym", "evidence": [ { "id": "B8JLW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JLW4/entry#names_and_taxonomy" } ] }, { "name": "c18h3orf33 homolog", "type": "synonym", "evidence": [ { "id": "NP_001138268", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138268" } ] }, { "name": "protein C3orf33 homolog", "type": "synonym", "evidence": [ { "id": "NP_001138268", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138268" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: BC128882.1, GDQQ01020075.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4476758 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000018.1. On Jan 25, 2009 this sequence version replaced XP_694177.2.", "evidence": [ { "database": "RefSeq", "id": "NP_001138268", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138268" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JLW4", "url": "https://www.uniprot.org/uniprotkb/B8JLW4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "c18h3orf33", "url": "https://www.uniprot.org/uniprotkb/B8JLW4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061121-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061121-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000040582", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000040582", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "565816", "url": "https://www.ncbi.nlm.nih.gov/gene/565816", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR035437", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035437", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042421", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042421", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565816", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565816", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ETWKENM", "url": "https://omabrowser.org/oma/group/ETWKENM/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JLW4", "url": "https://www.orthodb.org/?gene=B8JLW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR28434", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28434", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR28434:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR28434:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001138268", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138268", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JLW4", "url": "https://www.uniprot.org/uniprotkb/B8JLW4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JLW4-1", "url": "https://www.uniprot.org/uniprotkb/B8JLW4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061121-2", "url": "https://zfin.org/ZDB-GENE-061121-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPSVPADNTDDAKPSKNFVALLSNFADDHLTVVRSISTCIGLAGLLIVARSIRLMTKFGSGTDIPARFIERNIIIRGRLRNITEKGLEVEHIPISVPLLSRLLAKRQTEALLDVRLAGVELTSEGHHWIGQQLRPAETVWLRLIARQNETLHCLVSVNKGSLFNTCVNEELLRLGLARTSPLVVLDPHSQIYWSLYKRLLRAESKAEKKGKGLWKEESRWERFTDVLRNNMLLVSLKKLFKWRSGTKEK", "length": 249, "header": "tr|B8JLW4-1|B8JLW4_DANRE Isoform 1 of Protein C3orf33 homolog OS=Danio rerio OX=7955 GN=c18h3orf33 PE=4 SV=1 CANONICAL=B8JLW4-1" }, "isoforms": [ { "isoform_ac": "B8JLW4-1", "url": "https://www.uniprot.org/uniprotkb/B8JLW4/entry#B8JLW4-1", "sequence": { "sequence": "MPSVPADNTDDAKPSKNFVALLSNFADDHLTVVRSISTCIGLAGLLIVARSIRLMTKFGSGTDIPARFIERNIIIRGRLRNITEKGLEVEHIPISVPLLSRLLAKRQTEALLDVRLAGVELTSEGHHWIGQQLRPAETVWLRLIARQNETLHCLVSVNKGSLFNTCVNEELLRLGLARTSPLVVLDPHSQIYWSLYKRLLRAESKAEKKGKGLWKEESRWERFTDVLRNNMLLVSLKKLFKWRSGTKEK", "length": 249, "header": "tr|B8JLW4-1|B8JLW4_DANRE Isoform 1 of Protein C3orf33 homolog OS=Danio rerio OX=7955 GN=c18h3orf33 PE=4 SV=1 CANONICAL=B8JLW4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Evolution and origin of vomeronasal-type odorant receptor gene repertoire in fishes.", "journal": "BMC Evol. Biol.", "date": "2006", "authors": "Hashiguchi Yasuyuki, Nishida Mutsumi", "evidence": [ { "database": "UniProtKB", "id": "B8JLW4", "url": "https://www.uniprot.org/uniprotkb/B8JLW4" } ], "reference": [ { "type": "PubMed", "id": "17014738", "url": "https://glygen.org/publication/PubMed/17014738" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JLW4", "url": "https://www.uniprot.org/uniprotkb/B8JLW4" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "B8JLW4", "url": "https://www.uniprot.org/uniprotkb/B8JLW4" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] } ], "pathway": [ { "id": "dre:565816", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565816", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2K3F1-1", "protein_name": "Similar to human chromosome 3 open reading frame 33", "gene_name": "C2h3orf33", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAPLPASLGSQASDRDRGEANVVTRMSQWADNHLRLVQNISTGMAIAGIVLLIRSVRLTSKFTTSSDIPVEFIRKKVKLRGRLQRITECGLEIEHVPITLPFISSWKQEPCGVLLVKLAGVELTEAGKVWLQKELRPSQLLWFQLLGKENSELFCYLLVNKGGYFNVNLNEEILRRGLGKTVLVKGLNYDSKTHWKIHRKLLKAELTALKKGEGIWKEESEKESYFRKLKDSWRERWTKDNDLKTAGPGLSATKEGHYDRFRRAYGSWKDNMGNYSLVLKLREFVSRLHFRRKG", "length": 294 }, "evidence": [ { "id": "MGI:3607716", "url": "https://alliancegenome.org/gene/MGI:3607716#orthology", "database": "AGR" }, { "id": "HGNC:26434", "url": "https://alliancegenome.org/gene/HGNC:26434#orthology", "database": "AGR" }, { "id": "B8JLW4", "url": "https://omabrowser.org/oma/group/B8JLW4/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1B722-1", "protein_name": "Chromosome 1 C3orf33 homolog", "gene_name": "C1H3orf33", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MAGQPATPATPPPNRDGAAPNVVARISQWADDHLRLVRNISTVMAMAGVMLLLRSVRLTSKFTRSSDIPVEFIRKNVKLRGRLHRITENGLEIEHIPIALPAISSWRKEPCGVLLIKLAGVELTETGKVWLQKELKPSQVLWFQLLGKENSALFCYLLVNKGRFFSVNLNEEILRRGLGKTVLVKGLSHDSKIYWRIHRNLLKAELTALKKGEGVWKEDSEKESYLEKLKGSWREIWKKDSYFKKNGSDFNLKKESYYDKFKRSYETWKETVNNYSLILKFRELMSRIHFRRKE", "length": 294 }, "evidence": [ { "id": "B8JLW4", "url": "https://omabrowser.org/oma/group/B8JLW4/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6P1S2-1", "protein_name": "Mitochondrial inner membrane subdomain organizer 1", "gene_name": "MISO1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAGQPAATGSPSADKDGMEPNVVARISQWADDHLRLVRNISTGMAIAGIMLLLRSIRLTSKFTSSSDIPVEFIRRNVKLRGRLRRITENGLEIEHIPITLPIIASLRKEPRGALLVKLAGVELAETGKAWLQKELKPSQLLWFQLLGKENSALFCYLLVSKGGYFSVNLNEEILRRGLGKTVLVKGLKYDSKIYWTVHRNLLKAELTALKKGEGIWKEDSEKESYLEKFKDSWREIWKKDSFLKTTGSDFSLKKESYYEKLKRTYEIWKDNMNNCSLILKFRELISRINFRRKG", "length": 294 }, "evidence": [ { "id": "MGI:3607716", "url": "https://alliancegenome.org/gene/MGI:3607716#orthology", "database": "AGR" }, { "id": "HGNC:26434", "url": "https://alliancegenome.org/gene/HGNC:26434#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061121-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061121-2#orthology", "database": "AGR" }, { "id": "B8JLW4", "url": "https://omabrowser.org/oma/group/B8JLW4/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7K332-1", "protein_name": "Mitochondrial inner membrane subdomain organizer", "gene_name": "MISO", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MEAAKDFAVAKYQDLCNFLERDTRGSELAIYGTSAIMLAVAYAKRKPAYLVRQFKQPSHIPERLINERVMHTGKIAGVKQQEQDTLLMIQHRPLFPIFTSSKRLLPVKLPGVRVNANGYSWLQQCLIGREATFLPLKSAKGQDFVVCQLCLVHPPRGNRLLDVSETLLKLRFARFVQDAAAAVKKNGKYYQHLKKVEQTTAEKEAWLSWAAGYPYIWRRYNELRQRWLPKEKLLPELVR", "length": 239 }, "evidence": [ { "id": "MGI:3607716", "url": "https://alliancegenome.org/gene/MGI:3607716#orthology", "database": "AGR" }, { "id": "HGNC:26434", "url": "https://alliancegenome.org/gene/HGNC:26434#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8BN57-1", "protein_name": "Mitochondrial inner membrane subdomain organizer 1", "gene_name": "Miso1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARPPASLGSQAPDRDRGEANVVTRVSQWADNHLRLVQNISTGMAIAGIMLLIRSVRLTSKFTTSSDIPVEFIRKKVKLRGRLQRITECGLEIEHIPITLPFISSWKEEPRGVLLVKLAGVELTESGKVWLQAELKPSQLLWFQLLGKEDSALFCYLLVNKGGYFNVNLNEEILRRGLGKTVLVKGLNYDSKTHWKIHRNLLKAELTALKKGEGIWKEESEKESYFRKLKDSWRERWTKDNDLKPAGADLGSTKDSYHDSRRRASGKGKDSVSNYSFFLKLREFVSRLHFWRKG", "length": 294 }, "evidence": [ { "id": "MGI:3607716", "url": "https://alliancegenome.org/gene/MGI:3607716#orthology", "database": "AGR" }, { "id": "HGNC:26434", "url": "https://alliancegenome.org/gene/HGNC:26434#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061121-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061121-2#orthology", "database": "AGR" }, { "id": "B8JLW4", "url": "https://omabrowser.org/oma/group/B8JLW4/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "B8JLW4", "url": "https://www.uniprot.org/uniprotkb/B8JLW4" } ], "pmid": "" }, { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "B8JLW4", "url": "https://www.uniprot.org/uniprotkb/B8JLW4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 148, "end_pos": 150, "annotation": "n_glycosylation_sequon" }, { "start_pos": 81, "end_pos": 83, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 148, "end_pos": 150 }, { "start_pos": 81, "end_pos": 83 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JM00-1", "uniprot_ac": "B8JM00", "uniprot_id": "B8JM00_DANRE", "mass": { "chemical_mass": 38851.0, "monoisotopic_mass": 38851.0 }, "refseq": { "ac": "XP_017208873", "name": "zinc finger protein 1003", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208873" }, "gene_names": [ { "name": "znf1003", "type": "recommended", "evidence": [ { "id": "B8JM00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JM00" } ] }, { "name": "znf1003", "type": "synonym", "evidence": [ { "id": "XP_017208873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208873" } ] } ], "protein_names": [ { "name": "Zinc finger protein 1003", "type": "synonym", "evidence": [ { "id": "B8JM00", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JM00/entry#names_and_taxonomy" } ] }, { "name": "zinc finger protein 1003", "type": "synonym", "evidence": [ { "id": "XP_017208873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208873" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017208873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017208873" } ] }, { "annotation": "May be involved in transcriptional regulation.", "evidence": [ { "database": "UniProtKB", "id": "B8JM00", "url": "https://www.uniprot.org/uniprotkb/B8JM00#function" }, { "database": "UniProtKB", "id": "ARBA00003767", "url": "https://www.uniprot.org/uniprotkb/ARBA00003767#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JM00", "url": "https://www.uniprot.org/uniprotkb/B8JM00" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "znf1003", "url": "https://www.uniprot.org/uniprotkb/B8JM00", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-080219-42", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-080219-42", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092605", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092605", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "793476", "url": "https://www.ncbi.nlm.nih.gov/gene/793476", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050717", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050717", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:793476", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793476", "database": "KEGG Pathway", 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annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_002660625", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002660625" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JM30", "url": "https://www.uniprot.org/uniprotkb/B8JM30" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch73-343l4.8", "url": "https://www.uniprot.org/uniprotkb/B8JM30", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-159", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-159", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000077975", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000077975", "database": "Bgee", "categories": [ "Gene 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"categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "B8JM30", "url": "https://www.uniprot.org/uniprotkb/B8JM30" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "external side of plasma membrane", "id": "GO:0009897", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009897", "evidence": [ { "database": "UniProtKB", "id": "B8JM30", "url": "https://www.uniprot.org/uniprotkb/B8JM30" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "B8JM30", "url": "https://www.uniprot.org/uniprotkb/B8JM30" } ], "pmid": "" }, { "name": "pattern recognition receptor activity", "id": "GO:0038187", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0038187", "evidence": [ { "database": "UniProtKB", "id": "B8JM30", "url": "https://www.uniprot.org/uniprotkb/B8JM30" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 64, "end_pos": 66, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8JM30", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JM30" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 60, "end_pos": 169, "start_aa": "Phe", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 64, "end_pos": 66 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "B8JMC2-1", "uniprot_ac": "B8JMC2", "uniprot_id": "B8JMC2_DANRE", "mass": { "chemical_mass": 26965.0, "monoisotopic_mass": 26965.0 }, "refseq": { "ac": "NP_001014343", "name": "SERTA domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014343" }, "gene_names": [ { "name": "sertad3", "type": "recommended", "evidence": [ { "id": "B8JMC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JMC2" } ] }, { "name": "CH73-262H23.2", "type": "synonym", "evidence": [ { "id": "NP_001014343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014343" }, { "id": "B8JMC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JMC2" } ] }, { "name": "sertad3", "type": "synonym", "evidence": [ { "id": "NP_001014343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014343" } ] }, { "name": "zgc:113340", "type": "synonym", "evidence": [ { "id": "NP_001014343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014343" }, { "id": "B8JMC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JMC2" } ] } ], "protein_names": [ { "name": "SERTA domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "NP_001014343", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014343" }, { "id": "B8JMC2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JMC2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CK679836.1, GFIL01044725.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505385 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000018.1. On Jun 16, 2016 this sequence version replaced NP_001014343.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001014343", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014343" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JMC2", "url": "https://www.uniprot.org/uniprotkb/B8JMC2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sertad3", "url": "https://www.uniprot.org/uniprotkb/B8JMC2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-050327-34", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-34", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000097473", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000097473", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "541508", "url": "https://www.ncbi.nlm.nih.gov/gene/541508", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR009263", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009263", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052262", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052262", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:541508", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:541508", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DWGSAES", "url": "https://omabrowser.org/oma/group/DWGSAES/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JMC2", "url": "https://www.orthodb.org/?gene=B8JMC2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16277", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16277", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16277:SF13", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16277:SF13", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF06031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF06031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001014343", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001014343", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JMC2", "url": "https://www.uniprot.org/uniprotkb/B8JMC2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JMC2-1", "url": "https://www.uniprot.org/uniprotkb/B8JMC2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-050327-34", "url": "https://zfin.org/ZDB-GENE-050327-34", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MVARGQKRKLCRDDEGAGSAWESQLQSVLDISMDKYQRDQALVEPSLLRSVLINNTLRQVQSEVRAQVDSLSPLNQSQPKPQDFPQILSPVDRNASLFSLNAENVEEDITGWTSEEDFSLSSAISAILKDLDAIIDGPSQRSPLGSIENLPGCSSLRAEKSYFRTEATCPGQDVSLDKLLMDIDSSVFEPEVNLLQGFSDDLVKYLPSLSKSPSASPSVVSPGQATWEIQEIEHVMDFLMRTYP", "length": 244, "header": "tr|B8JMC2-1|B8JMC2_DANRE Isoform 1 of SERTA domain-containing protein 3 OS=Danio rerio OX=7955 GN=sertad3 PE=4 SV=1 CANONICAL=B8JMC2-1" }, "isoforms": [ { "isoform_ac": "B8JMC2-1", "url": "https://www.uniprot.org/uniprotkb/B8JMC2/entry#B8JMC2-1", "sequence": { "sequence": "MVARGQKRKLCRDDEGAGSAWESQLQSVLDISMDKYQRDQALVEPSLLRSVLINNTLRQVQSEVRAQVDSLSPLNQSQPKPQDFPQILSPVDRNASLFSLNAENVEEDITGWTSEEDFSLSSAISAILKDLDAIIDGPSQRSPLGSIENLPGCSSLRAEKSYFRTEATCPGQDVSLDKLLMDIDSSVFEPEVNLLQGFSDDLVKYLPSLSKSPSASPSVVSPGQATWEIQEIEHVMDFLMRTYP", "length": 244, "header": "tr|B8JMC2-1|B8JMC2_DANRE Isoform 1 of SERTA domain-containing protein 3 OS=Danio rerio OX=7955 GN=sertad3 PE=4 SV=1 CANONICAL=B8JMC2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2002", "authors": "Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA", "evidence": [ { "database": "UniProtKB", "id": "B8JMC2", "url": "https://www.uniprot.org/uniprotkb/B8JMC2" } ], "reference": [ { "type": "PubMed", "id": "12477932", "url": "https://glygen.org/publication/PubMed/12477932" } ] }, { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "B8JMC2", "url": "https://www.uniprot.org/uniprotkb/B8JMC2" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] } ], "pathway": [ { "id": "dre:541508", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:541508", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "I3LLZ3-1", "protein_name": "SERTA domain containing 3", "gene_name": "SERTAD3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVGLKRKHSDLEEEEEDEKWDWSPTGLRSYQQALLRISLDKVQRSLGPRAPSLRRHVLIHNTLQQLQAALCLTPAPALPPEPLFLGEEDFSLSTTIGSILRELETSMDETEPPPNPVAPPGPQNEVLPQPDPVFLEALSSRYLGDSGLDDFFLDIDTSAVEKEPALTPPEPPHNLFCAPGSWEWNELDHIMEIILGS", "length": 197 }, "evidence": [ { "id": "B8JMC2", "url": "https://omabrowser.org/oma/group/B8JMC2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q5BK27-1", "protein_name": "SERTA domain containing 3", "gene_name": "Sertad3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGGLKRKHSDLEEEEEDEKWDWSPTALRSYQQALLRISLDKVQRSLGPRAPSLRRHVLIHNTLQQLQAAIRLAPAPALPPEPLFLGEEDFSLSTTIGSILRELDTSTDELEPPLNPAASPGPHDEIMSQADPVFLEALSSRYLGDSGLDDFFLDIDTSAVERDTALPPPEPPHSLFCSPGSWEWNELDHIMEIILGS", "length": 197 }, "evidence": [ { "id": "RGD:1564271", "url": "https://alliancegenome.org/gene/RGD:1564271#orthology", "database": "AGR" }, { "id": "HGNC:17931", "url": "https://alliancegenome.org/gene/HGNC:17931#orthology", "database": "AGR" }, { "id": "MGI:2180697", "url": "https://alliancegenome.org/gene/MGI:2180697#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-34", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-34#orthology", "database": "AGR" }, { "id": "B8JMC2", "url": "https://omabrowser.org/oma/group/B8JMC2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P771-1", "protein_name": "SERTA domain containing 1", "gene_name": "Sertad1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLSKGLKRKREEEETMESLSVDSWWLDQSRPAVAQTPATVASSSLFDLSVVKLHHSLRQSEPDLRHLVLVVNTLRRIQASMEPTTVLPPEPIQPTAPSVADNFLSSSDAGLSASMASLLEDLSHIEDLNQVPQPQADEGPPGRSVGGVLPNLGALDLLGPATGCLLDDGLEGLFEDIDTSMYDSELWLPASEGLKPVPENGPAKEETPELDEAELDYLMDVLVGTQALERPPGPGR", "length": 236 }, "evidence": [ { "id": "HGNC:17932", "url": "https://alliancegenome.org/gene/HGNC:17932#orthology", "database": "AGR" }, { "id": "MGI:1913438", "url": "https://alliancegenome.org/gene/MGI:1913438#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9ERC3-1", "protein_name": "SERTA domain-containing protein 3", "gene_name": "Sertad3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGGLKRKHSDLEEEEEEEKWDWSPTALRSYQQALLRISLDKVQRSLGPRAPSLRRHVLIHNTLQQLQAAIRLAPAPALPPEPLFLGEEDFSLSTTIGSILRELDTSMDEMEPPLNPAASSSPQNEIVSQADPVFLEALSSRYLGDSGLDDFFLDIDTSAVEKDVALPPPEPPHSLFCSPGSWEWNELDHIMEIILGS", "length": 197 }, "evidence": [ { "id": "RGD:1564271", "url": "https://alliancegenome.org/gene/RGD:1564271#orthology", "database": "AGR" }, { "id": "HGNC:17931", "url": "https://alliancegenome.org/gene/HGNC:17931#orthology", "database": "AGR" }, { "id": "MGI:2180697", "url": "https://alliancegenome.org/gene/MGI:2180697#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-34", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-34#orthology", "database": "AGR" }, { "id": "B8JMC2", "url": "https://omabrowser.org/oma/group/B8JMC2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9JL10-1", "protein_name": "SERTA domain-containing protein 1", "gene_name": "Sertad1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLSKGLKRKREEEETMEALSVDSCWLDPSHPAVAQTPPTVASSSLFDLSVVKLHHSLRQSEPDLRHLVLVVNTLRRIQASMEPAPVLPPEPIQPPAPSVADSLLASSDAGLSASMASLLEDLNHIEDLNQAPQPQADEGPPGRSIGGISPNLGALDLLGPATGCLLDDGLEGLFEDIDTSMYDSELWLPASEGLKPGPENGPAKEEPPELDEAELDYLMDVLVGTQALERPPGPGR", "length": 236 }, "evidence": [ { "id": "HGNC:17932", "url": "https://alliancegenome.org/gene/HGNC:17932#orthology", "database": "AGR" }, { "id": "MGI:1913438", "url": "https://alliancegenome.org/gene/MGI:1913438#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-34", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-34#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9UHV2-1", "protein_name": "SERTA domain-containing protein 1", "gene_name": "SERTAD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLSKGLKRKREEEEEKEPLAVDSWWLDPGHTAVAQAPPAVASSSLFDLSVLKLHHSLQQSEPDLRHLVLVVNTLRRIQASMAPAAALPPVPSPPAAPSVADNLLASSDAALSASMASLLEDLSHIEGLSQAPQPLADEGPPGRSIGGAAPSLGALDLLGPATGCLLDDGLEGLFEDIDTSMYDNELWAPASEGLKPGPEDGPGKEEAPELDEAELDYLMDVLVGTQALERPPGPGR", "length": 236 }, "evidence": [ { "id": "HGNC:17932", "url": "https://alliancegenome.org/gene/HGNC:17932#orthology", "database": "AGR" }, { "id": "MGI:1913438", "url": "https://alliancegenome.org/gene/MGI:1913438#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-34", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-34#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9UJW9-1", "protein_name": "SERTA domain-containing protein 3", "gene_name": "SERTAD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVGGLKRKHSDLEEEEERWEWSPAGLQSYQQALLRISLDKVQRSLGPRAPSLRRHVLIHNTLQQLQAALRLAPAPALPPEPLFLGEEDFSLSATIGSILRELDTSMDGTEPPQNPVTPLGLQNEVPPQPDPVFLEALSSRYLGDSGLDDFFLDIDTSAVEKEPARAPPEPPHNLFCAPGSWEWNELDHIMEIILGS", "length": 196 }, "evidence": [ { "id": "RGD:1564271", "url": "https://alliancegenome.org/gene/RGD:1564271#orthology", "database": "AGR" }, { "id": "HGNC:17931", "url": "https://alliancegenome.org/gene/HGNC:17931#orthology", "database": "AGR" }, { "id": "MGI:2180697", "url": "https://alliancegenome.org/gene/MGI:2180697#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-050327-34", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-050327-34#orthology", "database": "AGR" }, { "id": "B8JMC2", "url": "https://omabrowser.org/oma/group/B8JMC2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "transcription coactivator activity", "id": "GO:0003713", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003713", "evidence": [ { "database": "UniProtKB", "id": "B8JMC2", "url": "https://www.uniprot.org/uniprotkb/B8JMC2" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "B8JMC2", "url": "https://www.uniprot.org/uniprotkb/B8JMC2" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B8JMC2", "url": "https://www.uniprot.org/uniprotkb/B8JMC2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 54, "end_pos": 56, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" }, { "start_pos": 94, "end_pos": 96, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], 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{ "start_pos": 94, "end_pos": 96 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8JME6-1", "uniprot_ac": "B8JME6", "uniprot_id": "B8JME6_DANRE", "mass": { "chemical_mass": 24770.0, "monoisotopic_mass": 24770.0 }, "refseq": { "ac": "NP_001138258", "name": "uncharacterized protein LOC555816 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138258" }, "gene_names": [ { "name": "si:ch1073-126c3.2", "type": "recommended", "evidence": [ { "id": "B8JME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JME6" } ] }, { "name": "fd36h06", "type": "synonym", "evidence": [ { "id": "NP_001138258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138258" }, { "id": "B8JME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JME6" } ] }, { "name": "si:ch1073-126c3.2", "type": "synonym", "evidence": [ { "id": "NP_001138258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138258" } ] }, { "name": "wu:fd36h06", "type": "synonym", "evidence": [ { "id": "NP_001138258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138258" }, { "id": "B8JME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JME6" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC555816 precursor", "type": "synonym", "evidence": [ { "id": "B8JME6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JME6/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC555816 precursor", "type": "synonym", "evidence": [ { "id": "NP_001138258", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138258" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GFIL01035305.1, EH498865.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## PREDICTED REFSEQ: This record has not been reviewed and the function is unknown. The reference sequence was derived from JBMGRA010000013.1. On Jun 5, 2025 this sequence version replaced NP_001138258.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001138258", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138258" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JME6", "url": "https://www.uniprot.org/uniprotkb/B8JME6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch1073-126c3.2", "url": "https://www.uniprot.org/uniprotkb/B8JME6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-4602", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4602", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000092858", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000092858", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "555816", "url": "https://www.ncbi.nlm.nih.gov/gene/555816", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "dre:555816", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555816", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KCGENPP", "url": "https://omabrowser.org/oma/group/KCGENPP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8JME6", "url": "https://www.orthodb.org/?gene=B8JME6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "NP_001138258", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001138258", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JME6", "url": "https://www.uniprot.org/uniprotkb/B8JME6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JME6-1", "url": "https://www.uniprot.org/uniprotkb/B8JME6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-4602", "url": "https://zfin.org/ZDB-GENE-030131-4602", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MESATIGRKWKQLLLFAFLSTLTHGQSHSSCLPADFSFDQLDKQLQNIKNCLETVSDNWTSYQHGNILNQLQALTDIIQRQDNKAFQKLLPENCPAPAVPENGGLLCLSVKDKIYCKPMCNAGYDFNFLRRSRLFEECSTATKHTWTTQYIGGNRLAICNKSHIAVSGAPSAYFPQGEDCHITKSNEQLTQNITNIFKSELAKVETTESESTKLLCGNINN", "length": 221, "header": "tr|B8JME6-1|B8JME6_DANRE Isoform 1 of Uncharacterized protein LOC555816 precursor OS=Danio rerio OX=7955 GN=si:ch1073-126c3.2 PE=4 SV=1 CANONICAL=B8JME6-1" }, "isoforms": [ { "isoform_ac": "B8JME6-1", "url": "https://www.uniprot.org/uniprotkb/B8JME6/entry#B8JME6-1", "sequence": { "sequence": "MESATIGRKWKQLLLFAFLSTLTHGQSHSSCLPADFSFDQLDKQLQNIKNCLETVSDNWTSYQHGNILNQLQALTDIIQRQDNKAFQKLLPENCPAPAVPENGGLLCLSVKDKIYCKPMCNAGYDFNFLRRSRLFEECSTATKHTWTTQYIGGNRLAICNKSHIAVSGAPSAYFPQGEDCHITKSNEQLTQNITNIFKSELAKVETTESESTKLLCGNINN", "length": 221, "header": "tr|B8JME6-1|B8JME6_DANRE Isoform 1 of Uncharacterized protein LOC555816 precursor OS=Danio rerio OX=7955 GN=si:ch1073-126c3.2 PE=4 SV=1 CANONICAL=B8JME6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Transcriptomic analyses of sexual dimorphism of the zebrafish liver and the effect of sex hormones.", "journal": "PLoS ONE", "date": "2013", "authors": "Zheng Weiling, Xu Hongyan, Lam Siew Hong, Luo Huaien, Karuturi R Krishna Murthy, Gong Zhiyuan", "evidence": [ { "database": "UniProtKB", "id": "B8JME6", "url": "https://www.uniprot.org/uniprotkb/B8JME6" } ], "reference": [ { "type": "PubMed", "id": "23349717", "url": "https://glygen.org/publication/PubMed/23349717" } ] }, { "title": "Gene responses in the central nervous system of zebrafish embryos exposed to the neurotoxicant methyl mercury.", "journal": "Environ. Sci. Technol.", "date": "2013", "authors": "Ho Nga Yu, Yang Lixin, Legradi Jessica, Armant Olivier, Takamiya Masanari, Rastegar Sepand, Str\u00e4hle Uwe", "evidence": [ { "database": "UniProtKB", "id": "B8JME6", "url": "https://www.uniprot.org/uniprotkb/B8JME6" } ], "reference": [ { "type": "PubMed", "id": "23458150", "url": "https://glygen.org/publication/PubMed/23458150" } ] }, { "title": "Phagocytosis of mycobacteria by zebrafish macrophages is dependent on the scavenger receptor Marco, a key control factor of pro-inflammatory signalling.", "journal": "Dev. Comp. Immunol.", "date": "2014", "authors": "Benard Erica L, Roobol Stefan J, Spaink Herman P, Meijer Annemarie H", "evidence": [ { "database": "UniProtKB", "id": "B8JME6", "url": "https://www.uniprot.org/uniprotkb/B8JME6" } ], "reference": [ { "type": "PubMed", "id": "25086293", "url": "https://glygen.org/publication/PubMed/25086293" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JME6", "url": "https://www.uniprot.org/uniprotkb/B8JME6" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Comprehensive and quantitative proteomic analyses of zebrafish plasma reveals conserved protein profiles between genders and between zebrafish and human.", "journal": "Sci. Rep.", "date": "2016", "authors": "Li Caixia, Tan Xing Fei, Lim Teck Kwang, Lin Qingsong, Gong Zhiyuan", "evidence": [ { "database": "UniProtKB", "id": "B8JME6", "url": "https://www.uniprot.org/uniprotkb/B8JME6" } ], "reference": [ { "type": "PubMed", "id": "27071722", "url": "https://glygen.org/publication/PubMed/27071722" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8JME6", "url": "https://www.uniprot.org/uniprotkb/B8JME6" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Gdnf Acts as a Germ Cell-Derived Growth Factor and Regulates the Zebrafish Germ Stem Cell Niche in Autocrine- and Paracrine-Dependent Manners.", "journal": "Cells", "date": "2022", "authors": "Doretto Lucas B, Butzge Arno J, Nakajima Rafael T, Martinez Emanuel R M, de Souza Beatriz Marques, Rodrigues Maira da Silva, Rosa Ivana F, Ricci Juliana M B, Tovo-Neto Aldo, Costa Daniel F, Malafaia Guilherme, Shao Changwei, N\u00f3brega Rafael H", "evidence": [ { "database": "UniProtKB", "id": "B8JME6", "url": "https://www.uniprot.org/uniprotkb/B8JME6" } ], "reference": [ { "type": "PubMed", "id": "35455974", "url": "https://glygen.org/publication/PubMed/35455974" } ] } ], "pathway": [ { "id": "dre:555816", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:555816", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 160, "end_pos": 162, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { 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isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417761" }, "gene_names": [ { "name": "si:ch1073-287p18.1", "type": "recommended", "evidence": [ { "id": "B8JMG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JMG6" } ] }, { "name": "si:ch1073-287p18.1", "type": "synonym", "evidence": [ { "id": "NP_001417761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417761" } ] } ], "protein_names": [ { "name": "UPF0598 protein C8orf82 homolog isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001417761", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417761" }, { "id": "B8JMG6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8JMG6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CN511409.1, GFIL01035329.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505380 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000020.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001417761", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417761" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8JMG6", "url": "https://www.uniprot.org/uniprotkb/B8JMG6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch1073-287p18.1", "url": "https://www.uniprot.org/uniprotkb/B8JMG6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081104-80", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-80", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000075765", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000075765", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "556730", "url": "https://www.ncbi.nlm.nih.gov/gene/556730", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028108", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028108", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:556730", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556730", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "B8JMG5", "url": "https://www.orthodb.org/?gene=B8JMG5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "B8JMG6", "url": "https://www.orthodb.org/?gene=B8JMG6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31449", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31449", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31449:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31449:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14956", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14956", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001417761", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001417761", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "B8JMG5", "url": "https://www.uniprot.org/uniprotkb/B8JMG5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JMG5-1", "url": "https://www.uniprot.org/uniprotkb/B8JMG5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JMG6", "url": "https://www.uniprot.org/uniprotkb/B8JMG6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8JMG6-1", "url": "https://www.uniprot.org/uniprotkb/B8JMG6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081104-80", "url": "https://zfin.org/ZDB-GENE-081104-80", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MRFVKRIFSRQCGLFCRNVSSYTQGQSPEARIREYFYYIDHQGQLFLDDTKVKNFVTCFKDQHFLVFFFSRLKVNQSGRYQQDFPFVSLCGRERNFLRCEDQPIVFTHLFSEVGLEDRLSYCGGGAKLSVPFRPQSLFMHPDSGRVYHPGPERTGGAGLLRSALAIEISAHFGYDTGQDGTAAQPTHFTWAGRRHALSKELEKHFPVQKDECMKIR", "length": 216, "header": "tr|B8JMG6-1|B8JMG6_DANRE Isoform 1 of UPF0598 protein C8orf82 homolog isoform 1 OS=Danio rerio OX=7955 GN=si:ch1073-287p18.1 PE=1 SV=1 CANONICAL=B8JMG6-1" }, "isoforms": [ { "isoform_ac": "B8JMG5-1", "url": "https://www.uniprot.org/uniprotkb/B8JMG6/entry#B8JMG5-1", "sequence": { "sequence": "MRFVKRIFSRQCGLFCRNVSSYTQGQSPEARIREYFYYIDHQGQLFLDDTKVKNFVTCFKGISISALYTLRPALLSFLLQPSESEPERPLSAGLPVCLALRTRAQLPALRGSAHSFHSPVLRGGA", "length": 125, "header": "tr|B8JMG5-1|B8JMG6_DANRE Computationally mapped isoform of UPF0598 protein C8orf82 homolog isoform 1 OS=Danio rerio OX=7955 GN=si:ch1073-287p18.1 PE=1 SV=1 CANONICAL=B8JMG6-1" }, "locus": {} }, { "isoform_ac": "B8JMG6-1", "url": "https://www.uniprot.org/uniprotkb/B8JMG6/entry#B8JMG6-1", "sequence": { "sequence": "MRFVKRIFSRQCGLFCRNVSSYTQGQSPEARIREYFYYIDHQGQLFLDDTKVKNFVTCFKDQHFLVFFFSRLKVNQSGRYQQDFPFVSLCGRERNFLRCEDQPIVFTHLFSEVGLEDRLSYCGGGAKLSVPFRPQSLFMHPDSGRVYHPGPERTGGAGLLRSALAIEISAHFGYDTGQDGTAAQPTHFTWAGRRHALSKELEKHFPVQKDECMKIR", "length": 216, "header": "tr|B8JMG6-1|B8JMG6_DANRE Isoform 1 of UPF0598 protein C8orf82 homolog isoform 1 OS=Danio rerio OX=7955 GN=si:ch1073-287p18.1 PE=1 SV=1 CANONICAL=B8JMG6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Transcriptomic analyses reveal novel genes with sexually dimorphic expression in the zebrafish gonad and brain.", "journal": "PLoS ONE", "date": "2008", "authors": "Sreenivasan Rajini, Cai Minnie, Bartfai Richard, Wang Xingang, Christoffels Alan, Orban Laszlo", "evidence": [ { "database": "UniProtKB", "id": "B8JMG5", "url": "https://www.uniprot.org/uniprotkb/B8JMG5" } ], "reference": [ { "type": "PubMed", "id": "18335061", "url": "https://glygen.org/publication/PubMed/18335061" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "B8JMG5", "url": "https://www.uniprot.org/uniprotkb/B8JMG5" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "B8JMG5", "url": "https://www.uniprot.org/uniprotkb/B8JMG5" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:556730", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:556730", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "F1RSQ0-1", "protein_name": "Chromosome 4 C8orf82 homolog", "gene_name": "C8orf82", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MWATRGALQAWTVGWARSSGSRAYGGGQGVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDPQFLVFFFSRLRPNRSGRYETSFPFLSPCGRERNFLRCEDRPVVFTHLLAAGPEPPRLSYCGGGEALTVPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYAPGAPELPSHVRWQGCRFALTMDLAPLLPAAPPR", "length": 218 }, "evidence": [ { "id": "B8JMG6", "url": "https://omabrowser.org/oma/group/B8JMG6/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "Q642A4-1", "protein_name": "UPF0598 protein C8orf82 homolog", "gene_name": "", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MWPPCGAMRNLALVLARSQRARACSGNERVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDLQFLVTFFSRLRPNHSGRYEASFPFLSLCGRERNFLRCEDRPVVFTHLLASDSESPRLSYCGGGEALAIPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYGPNSPTVPSHVQWQGRRIALTMDLAPLLLAAPPP", "length": 218 }, "evidence": [ { "id": "HGNC:33826", "url": "https://alliancegenome.org/gene/HGNC:33826#orthology", "database": "AGR" }, { "id": "MGI:1925941", "url": "https://alliancegenome.org/gene/MGI:1925941#orthology", "database": "AGR" }, { "id": "B8JMG6", "url": "https://omabrowser.org/oma/group/B8JMG6/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q6P1X6-1", "protein_name": "UPF0598 protein C8orf82", "gene_name": "C8orf82", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MWPPCGTLRTLALARSRGARACSGDGGVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDPQFLVTFFSRLRPNRSGRYEAAFPFLSPCGRERNFLRCEDRPVVFTHLLTADHGPPRLSYCGGGEALAVPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYGPGAPALPSHVRWQGRRLALTMDLAPLLLAARSP", "length": 216 }, "evidence": [ { "id": "HGNC:33826", "url": "https://alliancegenome.org/gene/HGNC:33826#orthology", "database": "AGR" }, { "id": "MGI:1925941", "url": "https://alliancegenome.org/gene/MGI:1925941#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-80", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-80#orthology", "database": "AGR" }, { "id": "B8JMG6", "url": "https://omabrowser.org/oma/group/B8JMG6/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8MKL1-1", "protein_name": "UPF0598 protein CG30010", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFILRSRSLTNLKFVRSPSISCRYVQYNQGQSPEPKIREYFYYIDHEGMLFLDDAKMKNFTSCFKEKDFLKFFFNRLRLNKTSRYESEFPYISLCGRERNFIRCDDTPVVFTEQLRKDDTEVLSYAHAGQVLTLPYEPHKLYMDPRNGRVYHPAAPQVGGIGLVRSKLAIELSQHFEFLAGEASPTHFQWNGERLELQNEWVNNTQRFPMNEDCK", "length": 215 }, "evidence": [ { "id": "HGNC:33826", "url": "https://alliancegenome.org/gene/HGNC:33826#orthology", "database": "AGR" }, { "id": "MGI:1925941", "url": "https://alliancegenome.org/gene/MGI:1925941#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8VE95-1", "protein_name": "UPF0598 protein C8orf82 homolog", "gene_name": "", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MWPPSGAVRNLALVLARSQRARTCSGVERVSYTQGQSPEPRTREYFYYVDHQGQLFLDDSKMKNFITCFKDLQFLVTFFSRLRPNHSGRYEASFPFLSLCGRERNFLRCEDRPVVFTHLLASDSESPRLSYCGGGEALAIPFEPARLLPLAANGRLYHPAPERAGGVGLVRSALAFELSACFEYGPSSPTVPSHVHWQGRRIALTMDLAPLLPAAPPP", "length": 218 }, "evidence": [ { "id": "HGNC:33826", "url": "https://alliancegenome.org/gene/HGNC:33826#orthology", "database": "AGR" }, { "id": "MGI:1925941", "url": "https://alliancegenome.org/gene/MGI:1925941#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081104-80", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081104-80#orthology", "database": "AGR" }, { "id": "B8JMG6", "url": "https://omabrowser.org/oma/group/B8JMG6/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 18, "end_pos": 20, "annotation": "n_glycosylation_sequon" }, { "start_pos": 75, "end_pos": 77, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 18, "end_pos": 20 }, { "start_pos": 75, "end_pos": 77 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "B8K0E7-1", "uniprot_ac": "B8K0E7", "uniprot_id": "B8K0E7_DANRE", "mass": { "chemical_mass": 48338.0, "monoisotopic_mass": 48338.0 }, "refseq": { "ac": "XP_002664757", "name": "F-box/LRR-repeat protein 20 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664757" }, "gene_names": [ { "name": "fbxl20", "type": "recommended", "evidence": [ { "id": "B8K0E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8K0E7" } ] }, { "name": "fbxl20", "type": "synonym", "evidence": [ { "id": "XP_002664757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664757" } ] } ], "protein_names": [ { "name": "F-box/LRR-repeat protein 20", "type": "recommended", "evidence": [ { "id": "B8K0E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8K0E7/entry#names_and_taxonomy" } ] }, { "name": "F-box and leucine-rich repeat protein 20", "type": "synonym", "evidence": [ { "id": "B8K0E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8K0E7/entry#names_and_taxonomy" } ] }, { "name": "F-box/LRR-repeat protein 20 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_002664757", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664757" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_002664757.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_002664757", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664757" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "B8K0E7", "url": "https://www.uniprot.org/uniprotkb/B8K0E7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fbxl20", "url": "https://www.uniprot.org/uniprotkb/B8K0E7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081031-27", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081031-27", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000075567", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000075567", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd22115", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd22115", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100331130", "url": "https://www.ncbi.nlm.nih.gov/gene/100331130", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001810", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001810", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR006553", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006553", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050648", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050648", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057207", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057207", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100331130", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331130", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LCNRIRY", "url": "https://omabrowser.org/oma/group/LCNRIRY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "B8K0E7", "url": "https://www.orthodb.org/?gene=B8K0E7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13318", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13318", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13318:SF47", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13318:SF47", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13382", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13382", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13382:SF62", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13382:SF62", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12937", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12937", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13516", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13516", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25372", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25372", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-8951664", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-983168", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-983168", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_002664757", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002664757", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58HZX9", "url": "https://www.uniprot.org/uniprotkb/A0AC58HZX9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HZX9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HZX9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8K0E7", "url": "https://www.uniprot.org/uniprotkb/B8K0E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "B8K0E7-1", "url": "https://www.uniprot.org/uniprotkb/B8K0E7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081031-27", "url": "https://zfin.org/ZDB-GENE-081031-27", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGKEVNGVSRSRFEMFSNNDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRSWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDSALRTFAQNCRNIELLSLNGCTKITDSTCNSLSKFCPKLKHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRCCPGLKGLFLKGCTQLEDEALKHIGGHCPELVTLNLQTCSQITDEGLITICRGCHRLQSLCVSGCANITDAILNALGQNCPRLRILEVARCSQLTDVGFTSLARNCHELEKMDLEECVQITDATLIQLSIHCPRLQVLSLSHCELITDDGIRQLGSGPCAHDRLEVIELDNCPLITDASLEHLKSCHSLDRIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCVLL", "length": 436, "header": "tr|B8K0E7-1|B8K0E7_DANRE Isoform 1 of F-box/LRR-repeat protein 20 OS=Danio rerio OX=7955 GN=fbxl20 PE=4 SV=1 CANONICAL=B8K0E7-1" }, "isoforms": [ { "isoform_ac": "A0AC58HZX9-1", "url": "https://www.uniprot.org/uniprotkb/B8K0E7/entry#A0AC58HZX9-1", "sequence": { "sequence": "MFSNNDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRSWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDSALRTFAQNCRNIELLSLNGCTKITDSTCNSLSKFCPKLKHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRCCPGLKGLFLKGCTQLEDEALKHIGGHCPELVTLNLQTCSQITDEGLITICRGCHRLQSLCVSGCANITDAILNALGQNCPRLRILEVARCSQLTDVGFTSLARNCHELEKMDLEECVQITDATLIQLSIHCPRLQVLSLSHCELITDDGIRQLGSGPCAHDRLEVIELDNCPLITDASLEHLKSCHSLDRIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCVLL", "length": 422, "header": "tr|A0AC58HZX9-1|A0AC58HZX9_DANRE Computationally mapped isoform of F-box/LRR-repeat protein 20 isoform X2 OS=Danio rerio OX=7955 GN=fbxl20 PE=4 SV=1 CANONICAL=B8K0E7-1" }, "locus": {} }, { "isoform_ac": "B8K0E7-1", "url": "https://www.uniprot.org/uniprotkb/B8K0E7/entry#B8K0E7-1", "sequence": { "sequence": "MGKEVNGVSRSRFEMFSNNDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRSWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDSALRTFAQNCRNIELLSLNGCTKITDSTCNSLSKFCPKLKHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRCCPGLKGLFLKGCTQLEDEALKHIGGHCPELVTLNLQTCSQITDEGLITICRGCHRLQSLCVSGCANITDAILNALGQNCPRLRILEVARCSQLTDVGFTSLARNCHELEKMDLEECVQITDATLIQLSIHCPRLQVLSLSHCELITDDGIRQLGSGPCAHDRLEVIELDNCPLITDASLEHLKSCHSLDRIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCVLL", "length": 436, "header": "tr|B8K0E7-1|B8K0E7_DANRE Isoform 1 of F-box/LRR-repeat protein 20 OS=Danio rerio OX=7955 GN=fbxl20 PE=4 SV=1 CANONICAL=B8K0E7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 417, "start_aa": "Thr", "end_pos": 417, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr417", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100331130", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100331130", "resource": "KEGG Pathway" }, { "id": "R-DRE-8951664", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-8951664", "resource": "Reactome", "description": "Neddylation" }, { "id": "R-DRE-983168", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-983168", "resource": "Reactome", "description": "Antigen processing: Ubiquitination & Proteasome degradation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A5G2QU00-1", "protein_name": "F-box/LRR-repeat protein 20", "gene_name": "FBXL20", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MVRVQSLAREFLHEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 436 }, "evidence": [ { "id": "B8K0E7", "url": "https://omabrowser.org/oma/group/B8K0E7/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0ZM14-1", "protein_name": "F-box and leucine rich repeat protein 20", "gene_name": "FBXL20", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MRRAAEPVPPGPSHTHGRWGEDISLSTCTHSTTTTTTIIIIIVAARAGREPSIAVLTHNWRPWKRDSSALNQMFSNNDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCQGVGDNALRTFAQNCRNIEVLNLNGCTKITDATCTSLSKFCSKLRHLDLASCTSITNLSLKALSEGCPLLEQLNISWCDQVTKDGVQALVRGCGGLKALSLKGCTQLEDEALKYIGANCPELVTLNLQTCLQITDDGLITICRGCHKLQSLCASGCCNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHDLEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDRLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 494 }, "evidence": [ { "id": "B8K0E7", "url": "https://omabrowser.org/oma/group/B8K0E7/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LPF2-1", "protein_name": "F-box/LRR-repeat protein 20", "gene_name": "Fbxl20", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSQEFKGPGFHPWDPYERRQELTSANSPLSYMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 453 }, "evidence": [ { "id": "MGI:1919444", "url": "https://alliancegenome.org/gene/MGI:1919444#orthology", "database": "AGR" }, { "id": "HGNC:24679", "url": "https://alliancegenome.org/gene/HGNC:24679#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A8DYA6-1", "protein_name": "F-box domain-containing protein", "gene_name": "Dmel\\CG9003", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MFASSAETGVMEVGGTSGTGTGSSSSNNGGGSSSNSGGAGGSIELLCPPSGSSSISGSASFSSNSGASGSSSQTHSTAVSSATDRSNNNGNNHNPSLQLNGNGGSNTRQHSSGSNSRQHSSSSSNSNSSNISPPPSSSSSSRSNNNNNNHSSNIISGFCSTIWRSATFGSATPVINPLPAVSINPKIMESSSDSCSLSSSTTPDVGLADQQRNMAGSAQDQSEDQSQTFLGATELDDELIKQLPKEVLLRVFSYLDVVSLCRCAQVCKYWNVLALDGSSWQKINLFDFQRDIEGPVIENISQRCRGFLKSLSLRGCQSVGDQSVRTLANHCHNIEHLDLSDCKKITDISTQSISRYCSKLTAINLHSCSNITDNSLKYLSDGCPNLMEINVSWCHLISENGVEALARGCVKLRKFSSKGCKQINDNAIMCLAKYCPDLMVLNLHSCETITDSSIRQLAANCHKLQKLCVSKCADLTDLTLLSLSQHNHLLNTLEVSGCRNFTDIGFQALGRNCKYLERMDLEECSQITDLTLAHLATGCPSLEKLTLSHCELITDDGIRHLTTGSCAAEILSVLELDNCPLITDRTLEHLVSCHNLQRIELFDCQLITRTAIRKLKNHLPNIKVHAYFAPGTPPAVTSGHRPRYCRCCEIL", "length": 651 }, "evidence": [ { "id": "MGI:1919444", "url": "https://alliancegenome.org/gene/MGI:1919444#orthology", "database": "AGR" }, { "id": "HGNC:24679", "url": "https://alliancegenome.org/gene/HGNC:24679#orthology", "database": "AGR" }, { "id": "B8K0E7", "url": "https://omabrowser.org/oma/group/B8K0E7/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q06479-1", "protein_name": "F-box protein YLR352W", "gene_name": "", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPDLKSKTLSSQSLGAAIPPEIVYQILTYQFRDLLRNDHPGTAEKFNENLTTFVKSNLTVNKTFSHICQVLIYRYCNLTTAKRFHGLLQTLKGNRCLCNKIEVADFQELTSIGLGRSSEMNKMIKNLTNETLLEFLMLTKANLREFLACENIQDDLDDNIIKYILSPGKVLSVVDFCGCSGTTFTESFIKALDKYYPNKSIDQYRLEPIQQNYQITCLGLNDCIDLPSHVLWKILKMLPELQKLDLSHTSIDDSTLYHGIPHWKNLTHLSLATCLQVTPRAVLEFFSHHPTITDPDNTSTLEWLNVSVIAHSSSWNEVHTMFLLKKLCQHGHNKTLQYLNIGGLPLHVAPSFGEDPISESTYYYQCRDSLQFIKWNFPKLKSLSIKGNSIPISTLVEFLTPIDQDHPNCAQKLKFLNISGNSYVNKWTIQDSLLYTCSPSLVALEVSFDSWQQIEKLNDRHEIIAYRYKNPNSVIKDISTAEQVKWKCYIDSSYGRRYWLYKTDPFLNRDDLDSKSNLTRYDFEGHKIIEIINQPDFLKFAQSKIMLGCGLVPQSGIRRKLCYRDLKPPVSQFLNRKGAISLGDTPLPIITPTLPRGGWRIIHNEDDNNSHVEDSQNHVNAIPRRNSLLSRPTLRSNNGSSSANPFAINVSPASQIRDGLYWDRSVHDLRELSLQEQRIQELADEQQELRTIANFEETDDEYLHDPDLQRRRSQLHLFESSRSRSGNKTRPSLTGEHSSSASFLSFSHFNHLHKRKNYYFTHPDEFVYDPKDPLTTQRYRLHFEIVNEYQVFGCIERGMYRYYSLKA", "length": 807 }, "evidence": [ { "id": "MGI:1919444", "url": "https://alliancegenome.org/gene/MGI:1919444#orthology", "database": "AGR" }, { "id": "HGNC:24679", "url": "https://alliancegenome.org/gene/HGNC:24679#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q58DG6-1", "protein_name": "F-box/LRR-repeat protein 20", "gene_name": "FBXL20", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 436 }, "evidence": [ { "id": "B8K0E7", "url": "https://omabrowser.org/oma/group/B8K0E7/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q96IG2-1", "protein_name": "F-box/LRR-repeat protein 20", "gene_name": "FBXL20", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 436 }, "evidence": [ { "id": "MGI:1919444", "url": "https://alliancegenome.org/gene/MGI:1919444#orthology", "database": "AGR" }, { "id": "HGNC:24679", "url": "https://alliancegenome.org/gene/HGNC:24679#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081031-27", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081031-27#orthology", "database": "AGR" }, { "id": "B8K0E7", "url": "https://omabrowser.org/oma/group/B8K0E7/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CZV8-1", "protein_name": "F-box/LRR-repeat protein 20", "gene_name": "Fbxl20", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLALDGSNWQRIDLFDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIEVLSLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCDQVTKDGIQALVRGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLITICRGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHELEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIELDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPPSVGGSRQRFCRCCIIL", "length": 436 }, "evidence": [ { "id": "MGI:1919444", "url": "https://alliancegenome.org/gene/MGI:1919444#orthology", "database": "AGR" }, { "id": "HGNC:24679", "url": "https://alliancegenome.org/gene/HGNC:24679#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081031-27", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081031-27#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "B8K0E7", "url": "https://www.uniprot.org/uniprotkb/B8K0E7" } ], "pmid": "" }, { "name": "SCF ubiquitin ligase complex", "id": "GO:0019005", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019005", "evidence": [ { "database": "UniProtKB", "id": "B8K0E7", "url": "https://www.uniprot.org/uniprotkb/B8K0E7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "SCF-dependent proteasomal ubiquitin-dependent protein catabolic process", "id": "GO:0031146", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0031146", "evidence": [ { "database": "UniProtKB", "id": "B8K0E7", "url": "https://www.uniprot.org/uniprotkb/B8K0E7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 158, "end_pos": 160, "annotation": "n_glycosylation_sequon" }, { "start_pos": 175, "end_pos": 177, "annotation": "n_glycosylation_sequon" }, { "start_pos": 259, "end_pos": 261, "annotation": "n_glycosylation_sequon" }, { "start_pos": 84, "end_pos": 86, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "B8K0E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/B8K0E7" }, { "id": "PS50181", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50181" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "F-box", "eco_id": "ECO_0000259", "start_pos": 22, "end_pos": 68, "start_aa": "Ala", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 417 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 158, "end_pos": 160 }, { "start_pos": 175, "end_pos": 177 }, { "start_pos": 259, "end_pos": 261 }, { "start_pos": 84, "end_pos": 86 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EXH8-1", "uniprot_ac": "E7EXH8", "uniprot_id": "E7EXH8_DANRE", "mass": { "chemical_mass": 49110.0, "monoisotopic_mass": 49110.0 }, "refseq": { "ac": "XP_001339641", "name": "UNC93-like protein MFSD11 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339641" }, "gene_names": [ { "name": "LOC799265", "type": "recommended", "evidence": [ { "id": "E7EXH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXH8" } ] }, { "name": "LOC799265", "type": "synonym", "evidence": [ { "id": "XP_001339641", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339641" } ] } ], "protein_names": [ { "name": "UNC93-like protein MFSD11 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001339641", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339641" }, { "id": "E7EXH8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXH8/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133178) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001339641.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001339641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339641" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EXH8", "url": "https://www.uniprot.org/uniprotkb/E7EXH8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC799265", "url": "https://www.uniprot.org/uniprotkb/E7EXH8", "locus": {} } ], "crossref": [ { "id": "ENSDARG00000104568", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000104568", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "799265", "url": "https://www.ncbi.nlm.nih.gov/gene/799265", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR010291", "url": "https://www.ebi.ac.uk/interpro/entry/IPR010291", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036259", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036259", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051617", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051617", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "EMTFYTG", "url": "https://omabrowser.org/oma/group/EMTFYTG/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EXH8", "url": "https://www.orthodb.org/?gene=E7EXH8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23294", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23294", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23294:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23294:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05978", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05978", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001339641", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001339641", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58J3H3", "url": "https://www.uniprot.org/uniprotkb/A0AC58J3H3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J3H3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J3H3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J3I0", "url": "https://www.uniprot.org/uniprotkb/A0AC58J3I0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58J3I0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58J3I0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EXH8", "url": "https://www.uniprot.org/uniprotkb/E7EXH8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EXH8-1", "url": "https://www.uniprot.org/uniprotkb/E7EXH8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MMADIRTYNVVVLGIGFLLIFTAFTTCGNIEQTVVKSLNSTNFTGSGYHSLGIIYGVFSFCNILAPTIVAVIGARFTMFLSGILYSGYIAVFIIPSTWSFYFTSVVIGFGAAMLWTAQGHFLVENSDASTINRNTGVFWALLQCSMLFGNLYVYFDWKGKTEISDRERKIMFTALLVISVLGTLSFLALRKVRQLEEALSEEEGQSLLSARFIYKQKAASAVTEAKTELKTIVEIFKSKTILLLSFCMAYSGLELSFYSGVYGTCIGATEYFGNSAKGLIGISGIVVGIGEIVGGGLFGLVLKNNRFRRTSVVFLGMVVHFVAFYLIFLNIPDDAPVVLQTSSQHNPYLAPSVSIALLCSFLLGLGDSCFNTQLYSILGRAYAEQSAPAFAIFKFIQSVSAAVAFFYSGYVLLTWQLLVMVIMGFIGTLCFFMVERMQNMSADAQEY", "length": 447, "header": "tr|E7EXH8-1|E7EXH8_DANRE Isoform 1 of UNC93-like protein MFSD11 isoform X1 OS=Danio rerio OX=7955 GN=LOC799265 PE=3 SV=1 CANONICAL=E7EXH8-1" }, "isoforms": [ { "isoform_ac": "A0AC58J3H3-1", "url": "https://www.uniprot.org/uniprotkb/E7EXH8/entry#A0AC58J3H3-1", "sequence": { "sequence": "MLPPSTGTQECFGRYCSADRERKIMFTALLVISVLGTLSFLALRKVRQLEEALSEEEGQSLLSARFIYKQKAASAVTEAKTELKTIVEIFKSKTILLLSFCMAYSGLELSFYSGVYGTCIGATEYFGNSAKGLIGISGIVVGIGEIVGGGLFGLVLKNNRFRRTSVVFLGMVVHFVAFYLIFLNIPDDAPVVLQTSSQHNPYLAPSVSIALLCSFLLGLGDSCFNTQLYSILGRAYAEQSAPAFAIFKFIQSVSAAVAFFYSGYVLLTWQLLVMVIMGFIGTLCFFMVERMQNMSADAQEY", "length": 301, "header": "tr|A0AC58J3H3-1|A0AC58J3H3_DANRE Computationally mapped isoform of UNC93-like protein MFSD11 isoform X3 OS=Danio rerio OX=7955 GN=LOC799265 PE=3 SV=1 CANONICAL=E7EXH8-1" }, "locus": {} }, { "isoform_ac": "A0AC58J3I0-1", "url": "https://www.uniprot.org/uniprotkb/E7EXH8/entry#A0AC58J3I0-1", "sequence": { "sequence": "MFLSGILYSGYIAVFIIPSTWSFYFTSVVIGFGAAMLWTAQGHFLVENSDASTINRNTGVFWALLQCSMLFGNLYVYFDWKGKTEISDRERKIMFTALLVISVLGTLSFLALRKVRQLEEALSEEEGQSLLSARFIYKQKAASAVTEAKTELKTIVEIFKSKTILLLSFCMAYSGLELSFYSGVYGTCIGATEYFGNSAKGLIGISGIVVGIGEIVGGGLFGLVLKNNRFRRTSVVFLGMVVHFVAFYLIFLNIPDDAPVVLQTSSQHNPYLAPSVSIALLCSFLLGLGDSCFNTQLYSILGRAYAEQSAPAFAIFKFIQSVSAAVAFFYSGYVLLTWQLLVMVIMGFIGTLCFFMVERMQNMSADAQEY", "length": 370, "header": "tr|A0AC58J3I0-1|A0AC58J3I0_DANRE Computationally mapped isoform of UNC93-like protein MFSD11 isoform X2 OS=Danio rerio OX=7955 GN=LOC799265 PE=3 SV=1 CANONICAL=E7EXH8-1" }, "locus": {} }, { "isoform_ac": "E7EXH8-1", "url": "https://www.uniprot.org/uniprotkb/E7EXH8/entry#E7EXH8-1", "sequence": { "sequence": "MMADIRTYNVVVLGIGFLLIFTAFTTCGNIEQTVVKSLNSTNFTGSGYHSLGIIYGVFSFCNILAPTIVAVIGARFTMFLSGILYSGYIAVFIIPSTWSFYFTSVVIGFGAAMLWTAQGHFLVENSDASTINRNTGVFWALLQCSMLFGNLYVYFDWKGKTEISDRERKIMFTALLVISVLGTLSFLALRKVRQLEEALSEEEGQSLLSARFIYKQKAASAVTEAKTELKTIVEIFKSKTILLLSFCMAYSGLELSFYSGVYGTCIGATEYFGNSAKGLIGISGIVVGIGEIVGGGLFGLVLKNNRFRRTSVVFLGMVVHFVAFYLIFLNIPDDAPVVLQTSSQHNPYLAPSVSIALLCSFLLGLGDSCFNTQLYSILGRAYAEQSAPAFAIFKFIQSVSAAVAFFYSGYVLLTWQLLVMVIMGFIGTLCFFMVERMQNMSADAQEY", "length": 447, "header": "tr|E7EXH8-1|E7EXH8_DANRE Isoform 1 of UNC93-like protein MFSD11 isoform X1 OS=Danio rerio OX=7955 GN=LOC799265 PE=3 SV=1 CANONICAL=E7EXH8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7EXH8", "url": "https://www.uniprot.org/uniprotkb/E7EXH8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 39, "end_pos": 41, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" }, { "start_pos": 439, "end_pos": 441, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 39, "end_pos": 41 }, { "start_pos": 42, "end_pos": 44 }, { "start_pos": 439, "end_pos": 441 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EXI7-1", "uniprot_ac": "E7EXI7", "uniprot_id": "E7EXI7_DANRE", "mass": { "chemical_mass": 65403.0, "monoisotopic_mass": 65403.0 }, "refseq": { "ac": "NP_001313466", "name": "protein FAM83C", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313466" }, "gene_names": [ { "name": "fam83c", "type": "recommended", "evidence": [ { "id": "E7EXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXI7" } ] }, { "name": "fam83c", "type": "synonym", "evidence": [ { "id": "NP_001313466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313466" } ] }, { "name": "im:7149063", "type": "synonym", "evidence": [ { "id": "NP_001313466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313466" }, { "id": "E7EXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXI7" } ] }, { "name": "sack1c", "type": "synonym", "evidence": [ { "id": "NP_001313466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313466" } ] } ], "protein_names": [ { "name": "Protein FAM83C", "type": "synonym", "evidence": [ { "id": "E7EXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXI7/entry#names_and_taxonomy" } ] }, { "name": "family with sequence similarity 83 member C", "type": "synonym", "evidence": [ { "id": "NP_001313466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313466" } ] }, { "name": "protein FAM83C", "type": "synonym", "evidence": [ { "id": "NP_001313466", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313466" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH459962.1, SRR26395013.135476.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505376, SAMEA3505377 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000006.1. On Jun 25, 2025 this sequence version replaced NP_001313466.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001313466", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313466" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EXI7", "url": "https://www.uniprot.org/uniprotkb/E7EXI7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam83c", "url": "https://www.uniprot.org/uniprotkb/E7EXI7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120201-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120201-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000075296", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000075296", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09183", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09183", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "570133", "url": "https://www.ncbi.nlm.nih.gov/gene/570133", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:570133", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570133", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QDQKRMT", "url": "https://omabrowser.org/oma/group/QDQKRMT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EXI7", "url": "https://www.orthodb.org/?gene=E7EXI7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001313466", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313466", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EXI7", "url": "https://www.uniprot.org/uniprotkb/E7EXI7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EXI7-1", "url": "https://www.uniprot.org/uniprotkb/E7EXI7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120201-3", "url": "https://zfin.org/ZDB-GENE-120201-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MISSEALRPTPNAARKPLGKLASRLEEVKNPWKQLSALELSHNETARLATDALLEHGEKEYKKVLHEEKELNFLSALEIRYITENVAKVGDADSGSNGVDLEEGDAVSELTSGTYFPMMSDEEPPMLELGWPELSTRMGPTEANIYFQRDKTKNVKDHIRSLISKAKKVIAIVMDIFTDVDLFCDLMEASNKRRVPVYILLDEKNLSHFLNMCSELDVQNSHLSNMRIRSVCGDTYCTKSGKKFTGQVQEKFMIIDCEEVIAGSYSFTWLSGQVHSNLVMHFSGHLTDCFDREFRCMYADSDIIERFHNPDEDGLPSYSYSYNMPAPNFGLDVLADYGSRERVYSENSSSQSSSSVSSIKAAPPGTKSVYKVNHDKKSQENTQKTPDKKDATSPVLHMPLAAHIGRGFPNEIHQTAERSSLGQSGGAEWSKIGNTDYLRSNIGGQTSKIQSLGLYSSPKPPSPTQQDNKISPKHRLTSPFLSKFTDLFTTKEKDLHAFQKVPPPRSSPFGGPDLSQNEPESKQGPPPPGPMPIDRMGPDKGIHRRDEKRMTLGHSKLDLVAQYNKMNKSKQVYSRFELKNNLPQ", "length": 584, "header": "tr|E7EXI7-1|E7EXI7_DANRE Isoform 1 of Protein FAM83C OS=Danio rerio OX=7955 GN=fam83c PE=3 SV=1 CANONICAL=E7EXI7-1" }, "isoforms": [ { "isoform_ac": "E7EXI7-1", "url": "https://www.uniprot.org/uniprotkb/E7EXI7/entry#E7EXI7-1", "sequence": { "sequence": "MISSEALRPTPNAARKPLGKLASRLEEVKNPWKQLSALELSHNETARLATDALLEHGEKEYKKVLHEEKELNFLSALEIRYITENVAKVGDADSGSNGVDLEEGDAVSELTSGTYFPMMSDEEPPMLELGWPELSTRMGPTEANIYFQRDKTKNVKDHIRSLISKAKKVIAIVMDIFTDVDLFCDLMEASNKRRVPVYILLDEKNLSHFLNMCSELDVQNSHLSNMRIRSVCGDTYCTKSGKKFTGQVQEKFMIIDCEEVIAGSYSFTWLSGQVHSNLVMHFSGHLTDCFDREFRCMYADSDIIERFHNPDEDGLPSYSYSYNMPAPNFGLDVLADYGSRERVYSENSSSQSSSSVSSIKAAPPGTKSVYKVNHDKKSQENTQKTPDKKDATSPVLHMPLAAHIGRGFPNEIHQTAERSSLGQSGGAEWSKIGNTDYLRSNIGGQTSKIQSLGLYSSPKPPSPTQQDNKISPKHRLTSPFLSKFTDLFTTKEKDLHAFQKVPPPRSSPFGGPDLSQNEPESKQGPPPPGPMPIDRMGPDKGIHRRDEKRMTLGHSKLDLVAQYNKMNKSKQVYSRFELKNNLPQ", "length": 584, "header": "tr|E7EXI7-1|E7EXI7_DANRE Isoform 1 of Protein FAM83C OS=Danio rerio OX=7955 GN=fam83c PE=3 SV=1 CANONICAL=E7EXI7-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 464, "start_aa": "Thr", "end_pos": 464, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr464", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7EXI7", "url": "https://www.uniprot.org/uniprotkb/E7EXI7" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "E7EXI7", "url": "https://www.uniprot.org/uniprotkb/E7EXI7" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:570133", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:570133", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A2ARK0-1", "protein_name": "Protein FAM83C", "gene_name": "Fam83c", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQGCQAGASIFFLIAANPDANHGASGGLGSRWIRTFSRIAPAGTQGMAGPLRSRVEELKRPWWRESSPLVLQHSEAARLAADALLERGEAAYLQVISEERELPFLSALDVDYMISHVRGVPELSEAQGSETLGQDLSMLSEVTSGTYFPMASDLDPPDLDLGWPEVPQATGFSPTQAVVHFQRDKGKSIKDLLRFLFSQAQTVVAVVMDVFTDMELLCDLMEASSRRGVPVYLLLAQEHLKYFLEMCYKMDLNGGHLVNMRVRSTCGDTYCSKAGRRFTGQALEKFVIIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGHIVEDFDREFRCLYAESQPVEGFCSNEDPLMPQVPRPPPVTLAFGPAVPSATGSSPSSNSLSSIKHSPLLARSSYLALPGGGGRNDMGMGSSSPGPAYHEAGGQPSLYRQLSDPNHISPPGPYRANLSKLGASPWSQSSPALNHSSTSPLTLAVGSPLLPSSRPLLHFTRGVPALSRLPENGLPASQDPSLPRGRWVPGTALETVEEKKVSLSQSHDHLDRLSPFSKAGEAGGPNSRVTPDSSSLQHRELALDDRRLSLSHSHSQLDLLSQGQGVLESGSLRPGELSLENRKLSLNHNHGQLDLLPQNPKPQAPKIPSDAYSSAGPSKPSLDDRRQTLGHSQLDLITKFGPFRSEGPGPSCPPEPSPVRMAGVGSADEKRLTLGHSKLDLITKYHQLQGARQKPEPGIPGAPVSGHQNGSSNDLFAPEKRLTLGHSKLDLITKYNKSKFKQLRSRFES", "length": 776 }, "evidence": [ { "id": "MGI:1918655", "url": "https://alliancegenome.org/gene/MGI:1918655#orthology", "database": "AGR" }, { "id": "HGNC:16121", "url": "https://alliancegenome.org/gene/HGNC:16121#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120201-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120201-3#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "M0R501-1", "protein_name": "Family with sequence similarity 83, member C", "gene_name": "Fam83c", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLGCQAGSSIFFLIAANPGASHGASCGLGSRWMQTFSRIVQAGTQGMAGPLRSRVEELKRPWWRESSPLVLQHSEAARLAADALLERGEAAYLQVISEERELPFLSALDVDYMISHVRGVPELSEAQGSETLGQDRLSMLSEVTSGTYFPMASDLDPPDLDLGWPEVPQATGFSPTQAVVHFQRDKGKSIKDLLRFLFSQAHTVVAVVMDVFTDMELLCDLMEASSRRGVPVYLLLAQEHLKYFLEMCYKMDLNGGHLVNMRVRSTCGDTYCSKAGRRFTGQALEKFVIIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGHIVEDFDREFRCLYAESQPVEGFCGNEDPLISQVPCPPPVTLAFGPGIPSPTGSSPSSNSLSSIKHSPLLARSSYLALPGGGGCSDMGMGSSSPGPAHHEAGAQPSLYRQLSDPNHISTPGPYRANLSKLGSSPWSQSSPALNHSSTSPLTLGVGSPLLPSSRPLLHFTRGVPALSRLPENGLPASQDPCLPRGRWVPGTALETVDEKKVSLSQSHDRLDRLIPFPKAGEAGVPSSRVSPNSSSLQHGEQVLDDRRLSLSHSYSQLDLLSQGQGSPESGSLRPGELSPEDRKLSLNHSHGPLDLLPQNPKPQASKIPPDAHSSARPGKPSVDDRRQTLGHSQLDLITKFGPFRSEGPGPSCPPEASPVRMAGVGSADEKRLTLGHSKLDLITKYHQLQGARQKPESGTPGAPISGQQNGSGNDLFAPEKRLTLGHSKLDLITKYNKSKFKQLRSRFES", "length": 777 }, "evidence": [ { "id": "MGI:1918655", "url": "https://alliancegenome.org/gene/MGI:1918655#orthology", "database": "AGR" }, { "id": "HGNC:16121", "url": "https://alliancegenome.org/gene/HGNC:16121#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q9BQN1-1", "protein_name": "Protein FAM83C", "gene_name": "FAM83C", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MFGGPGPGVLGAQGMAGPLRGRVEELKLPWWRESSPLVLRHSEAARLAADALLERGEAAYLRVISEERELPFLSALDVDYMTSHVRGGPELSEAQGQEASGPDRLSLLSEVTSGTYFPMASDIDPPDLDLGWPEVPQATGFSPTQAVVHFQRDKAKNIKDLLRFLFSQAHTVVAVVMDIFTDMELLCDLMEASSRRGVPVYLLLAQEHLRHFLEMCYKMDLNGEHLPNMRVRSTCGDTYCSKAGRRFTGQALEKFVLIDCEQVVAGSYSFTWLCSQAHTSMVLQLRGRIVEDFDREFRCLYAESQPVEGFCGGEDPLSPRALRPPPVALAFRPDVPSPTSSLPSSTSLSSIKQSPLMGRSSYLALPGGGDCSDTGVVSSSLGPARREASGQPSLHRQLSDPNHGSPPGLYRANLGKLGAYPWSQSSPALNHNSTSPLTLAVGSPLLPRSRPLLQFHRGAPALSRFPENGLPGSQEPSPLRGRWVPGTTLETVEEKEKKASPSQSRGQLDLLVPFPRAREVGDPDSGVTPNSGPLRPGEQAPEDRRLSPSQADSQLDLLSRALGTGGAPELGSLRPGDRALEDRRLSLNQSRGQSDLLMQYPKAQGSRVPLETNSSARPARRAPDERRQTLGHSQLDLITKFGPFRGEGPGPNGLPISSPARTAGAGSGDEKRLTLGHSKLDLITKYHQLHGARQGTEPGGPKGGHLNGGNSDLVRDEKRLTLGHSKLDLITKYNKSKFKQLRSRFES", "length": 747 }, "evidence": [ { "id": "MGI:1918655", "url": "https://alliancegenome.org/gene/MGI:1918655#orthology", "database": "AGR" }, { "id": "HGNC:16121", "url": "https://alliancegenome.org/gene/HGNC:16121#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120201-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120201-3#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytoskeleton", "id": "GO:0005856", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005856", "evidence": [ { "database": "UniProtKB", "id": "E7EXI7", "url": "https://www.uniprot.org/uniprotkb/E7EXI7" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E7EXI7", "url": "https://www.uniprot.org/uniprotkb/E7EXI7" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E7EXI7", "url": "https://www.uniprot.org/uniprotkb/E7EXI7" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" }, { "start_pos": 347, "end_pos": 349, "annotation": "n_glycosylation_sequon" }, { "start_pos": 43, "end_pos": 45, "annotation": "n_glycosylation_sequon" }, { "start_pos": 567, "end_pos": 569, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EXI7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXI7" }, { "id": "PF07894", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Scaffolding anchor of CK1", "eco_id": "ECO_0000259", "start_pos": 31, "end_pos": 302, "start_aa": "Pro", "end_aa": "Asp", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 464 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 }, { "start_pos": 347, "end_pos": 349 }, { "start_pos": 43, "end_pos": 45 }, { "start_pos": 567, "end_pos": 569 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7EXM1-1", "uniprot_ac": "E7EXM1", "uniprot_id": "E7EXM1_DANRE", "mass": { "chemical_mass": 76514.0, "monoisotopic_mass": 76514.0 }, "refseq": { "ac": "NP_001410060", "name": "wu:fc23c09 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410060" }, "gene_names": [ { "name": "fc23c09", "type": "recommended", "evidence": [ { "id": "E7EXM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXM1" } ] }, { "name": "fc23c09", "type": "synonym", "evidence": [ { "id": "NP_001410060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410060" } ] }, { "name": "wu:fc23c09", "type": "synonym", "evidence": [ { "id": "NP_001410060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410060" }, { "id": "E7EXM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXM1" } ] } ], "protein_names": [ { "name": "Wu:fc23c09 precursor", "type": "synonym", "evidence": [ { "id": "E7EXM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXM1/entry#names_and_taxonomy" } ] }, { "name": "podocan-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_001410060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410060" } ] }, { "name": "wu:fc23c09 precursor", "type": "synonym", "evidence": [ { "id": "NP_001410060", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410060" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588723.2068049.1, SRR32588722.37110441.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA898401, SAMN06350654 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000004.1. On Jul 5, 2023 this sequence version replaced XP_005164829.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001410060", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410060" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EXM1", "url": "https://www.uniprot.org/uniprotkb/E7EXM1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fc23c09", "url": "https://www.uniprot.org/uniprotkb/E7EXM1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-2988", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-2988", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "IPR000372", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000372", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001611", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001611", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR003591", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003591", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101882092", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882092", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7EXM1", "url": "https://www.orthodb.org/?gene=E7EXM1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45712:SF18", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45712:SF18", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13855", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13855", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-6794361", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6794361", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001410060", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001410060", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EXM1", "url": "https://www.uniprot.org/uniprotkb/E7EXM1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EXM1-1", "url": "https://www.uniprot.org/uniprotkb/E7EXM1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-2988", "url": "https://zfin.org/ZDB-GENE-030131-2988", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKPLVLLFWIFVVTVHTFVLQPSVNVTVLQNASAEGDLWGKQRLTRVMEALNAEEEKRSEEEVKIRGAEKETNNSNEEHGMKETEMGQTMIRTEDAEEKENQQGQSPDEPDTLDFTRPTLKQYNTPSISITSHPVLLTESATPPPSFSSTPQRPASAPETLYVITNTNLSSETTVETPKFHTPDAMGTTLLNESRTNDDLKVELHVMNVSELHLKEEVSVEVTALSARAGPTAKALPSTFTDKAKSKVAKHKDNKTLKGKKKKAVKGKPRKTTKVSKKAKKVKKLNHEQKLKPTTPSHFPYFEDNYCPSECSCYGRVVQCSDKHLVKIPYGIPYNSRYILLMNNKIDSIQLNLLSQYDSMEFLVLRNNRLTDSAVKKAFEGIQRLKRLYVERNLLRSIPTDLPATLEELRLDWNQISAMSNAAFERCPSLQILSLSNNTLLTIPPGVLLPLGSLRTLTLSYNQLASVPMQLPLSLRELYLRGNRIQRLQGDMFWGESELQILDLSLNRLTDKGLGKAALLNATGLESLNLEGNLLKRVPRHLPHTIKTLNLEGNFILSITKDAFVSMPQLEHLGLARNKIAKVALGAFRVLPLLHQLDMSYNALEQVPRQLPLWLHSATFMHNNIRSIPRDAFCWGRDNVSPLSRLVKVQLEYNMIDLGHLDTLAFRCLRGFQVVELY", "length": 678, "header": "tr|E7EXM1-1|E7EXM1_DANRE Isoform 1 of Wu:fc23c09 precursor OS=Danio rerio OX=7955 GN=fc23c09 PE=1 SV=2 CANONICAL=E7EXM1-1" }, "isoforms": [ { "isoform_ac": "E7EXM1-1", "url": "https://www.uniprot.org/uniprotkb/E7EXM1/entry#E7EXM1-1", "sequence": { "sequence": "MKPLVLLFWIFVVTVHTFVLQPSVNVTVLQNASAEGDLWGKQRLTRVMEALNAEEEKRSEEEVKIRGAEKETNNSNEEHGMKETEMGQTMIRTEDAEEKENQQGQSPDEPDTLDFTRPTLKQYNTPSISITSHPVLLTESATPPPSFSSTPQRPASAPETLYVITNTNLSSETTVETPKFHTPDAMGTTLLNESRTNDDLKVELHVMNVSELHLKEEVSVEVTALSARAGPTAKALPSTFTDKAKSKVAKHKDNKTLKGKKKKAVKGKPRKTTKVSKKAKKVKKLNHEQKLKPTTPSHFPYFEDNYCPSECSCYGRVVQCSDKHLVKIPYGIPYNSRYILLMNNKIDSIQLNLLSQYDSMEFLVLRNNRLTDSAVKKAFEGIQRLKRLYVERNLLRSIPTDLPATLEELRLDWNQISAMSNAAFERCPSLQILSLSNNTLLTIPPGVLLPLGSLRTLTLSYNQLASVPMQLPLSLRELYLRGNRIQRLQGDMFWGESELQILDLSLNRLTDKGLGKAALLNATGLESLNLEGNLLKRVPRHLPHTIKTLNLEGNFILSITKDAFVSMPQLEHLGLARNKIAKVALGAFRVLPLLHQLDMSYNALEQVPRQLPLWLHSATFMHNNIRSIPRDAFCWGRDNVSPLSRLVKVQLEYNMIDLGHLDTLAFRCLRGFQVVELY", "length": 678, "header": "tr|E7EXM1-1|E7EXM1_DANRE Isoform 1 of Wu:fc23c09 precursor OS=Danio rerio OX=7955 GN=fc23c09 PE=1 SV=2 CANONICAL=E7EXM1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "E7EXM1", "url": "https://www.uniprot.org/uniprotkb/E7EXM1" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Regulation of posterior body and epidermal morphogenesis in zebrafish by localized Yap1 and Wwtr1.", "journal": "Elife", "date": "2017", "authors": "Kimelman David, Smith Natalie L, Lai Jason Kuan Han, Stainier Didier Yr", "evidence": [ { "database": "UniProtKB", "id": "E7EXM1", "url": "https://www.uniprot.org/uniprotkb/E7EXM1" } ], "reference": [ { "type": "PubMed", "id": "29283341", "url": "https://glygen.org/publication/PubMed/29283341" } ] } ], "pathway": [ { "id": "dre:101882092", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882092", "resource": "KEGG Pathway" }, { "id": "R-DRE-6794361", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6794361", "resource": "Reactome", "description": "Neurexins and neuroligins" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E7EXM1", "url": "https://www.uniprot.org/uniprotkb/E7EXM1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 168, "end_pos": 170, "annotation": "n_glycosylation_sequon" }, { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" }, { "start_pos": 254, "end_pos": 256, "annotation": "n_glycosylation_sequon" }, { "start_pos": 25, "end_pos": 27, "annotation": "n_glycosylation_sequon" }, { "start_pos": 31, "end_pos": 33, "annotation": "n_glycosylation_sequon" }, { "start_pos": 437, "end_pos": 439, "annotation": "n_glycosylation_sequon" }, { "start_pos": 521, "end_pos": 523, "annotation": "n_glycosylation_sequon" }, { "start_pos": 639, "end_pos": 641, "annotation": "n_glycosylation_sequon" }, { "start_pos": 73, "end_pos": 75, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EXM1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXM1" }, { "id": "SM00013", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00013" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LRRNT", "eco_id": "ECO_0000259", "start_pos": 306, "end_pos": 338, "start_aa": "Tyr", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 168, "end_pos": 170 }, { "start_pos": 192, "end_pos": 194 }, { "start_pos": 208, "end_pos": 210 }, { "start_pos": 254, "end_pos": 256 }, { "start_pos": 25, "end_pos": 27 }, { "start_pos": 31, "end_pos": 33 }, { "start_pos": 437, "end_pos": 439 }, { "start_pos": 521, "end_pos": 523 }, { "start_pos": 639, "end_pos": 641 }, { "start_pos": 73, "end_pos": 75 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7EXN1-1", "uniprot_ac": "E7EXN1", "uniprot_id": "E7EXN1_DANRE", "mass": { "chemical_mass": 83775.0, "monoisotopic_mass": 83775.0 }, "refseq": { "ac": "XP_001333668", "name": "SANT and BTB domain regulator of class switch recombination isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001333668" }, "gene_names": [ { "name": "sanbr", "type": "recommended", "evidence": [ { "id": "E7EXN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXN1" } ] }, { "name": "sanbr", "type": "synonym", "evidence": [ { "id": "XP_001333668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001333668" } ] } ], "protein_names": [ { "name": "SANT and BTB domain regulator of class switch recombination isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001333668", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001333668" }, { "id": "E7EXN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXN1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 9, 2008 this sequence version replaced XP_001333668.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001333668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001333668" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EXN1", "url": "https://www.uniprot.org/uniprotkb/E7EXN1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sanbr", "url": "https://www.uniprot.org/uniprotkb/E7EXN1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100405-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100405-5", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000079857", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000079857", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00167", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00167", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "cd14733", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd14733", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "793832", "url": "https://www.ncbi.nlm.nih.gov/gene/793832", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001005", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001005", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR011333", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011333", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021777", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021777", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045902", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045902", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:793832", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793832", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHQAFLC", "url": "https://omabrowser.org/oma/group/CHQAFLC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EXN1", "url": "https://www.orthodb.org/?gene=E7EXN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20946", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20946", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20946:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20946:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF11822", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11822", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001333668", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001333668", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58HRJ6", "url": "https://www.uniprot.org/uniprotkb/A0AC58HRJ6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HRJ6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HRJ6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HRK1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HRK1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HRK1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HRK1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EXN1", "url": "https://www.uniprot.org/uniprotkb/E7EXN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EXN1-1", "url": "https://www.uniprot.org/uniprotkb/E7EXN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100405-5", "url": "https://zfin.org/ZDB-GENE-100405-5", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKEEHCFQRKPRIHLEQEMNRLCSVNNNFPYDNNLLVLDIVLSSLWASPQPINWENVAKLVPGFTPKECARRFEELKTTGSFPHVDEQCNPLTGAVSSPSESFSTYIKSNVLDITRDTGEPQSNQTTLSVSGLNVLPTGRGASIETEIADPAKNIEKTEENKSPNMVIHVCDEAKNLKQDFVCPRNLLVKEMRYFEEYLSVDPQRWDEVDISVHCDVQIFDWLMNYAKSHNTEQSHGKHTEKPKLEHSNVISILISSEFLKMETLVEECIQYCHKHMSAIIATPCNMNCINNNLAGRIADLFNHNEADDLKDKKDKFKSKLFQKKIERIFDHGYQNHDSPGNASTLYRCGLCLKLLTKETERKIPCVPNKINIDARGNIVFTHSRHKAWEVHEYVNCLYEELKSWVQVYWRIWGTINFLTCSRCKQAFLCTELGQCRYHPEAVVYPGIGADHRWHGLGVYPCCNQKVLRFDPSFMPKGCKIRDHIVSAADGGDCSDHNVNSTQTRILNDLLLHRDAVCVAESSEDLSVGSENVPGCDVMLEPGVLTAHRPKETTAFSLLKNWSLQLRQQSLLSEDEEYTTGSEVTEDEVGDEEDTSKKQAAKKARKSGKPLKRQVSSPNFHRKEKSGEKAPSRDTTPFTVSIQKNKWDSNRSMRYNQDAQREEDQRRMEEIIANLTKMRFGDQEQTKFKDTKEPAGGLYSRLEAQFKASSQSSARQSSSEKTLRAKTRSGPSRPT", "length": 735, "header": "tr|E7EXN1-1|E7EXN1_DANRE Isoform 1 of SANT and BTB domain regulator of class switch recombination isoform X1 OS=Danio rerio OX=7955 GN=sanbr PE=4 SV=1 CANONICAL=E7EXN1-1" }, "isoforms": [ { "isoform_ac": "A0AC58HRJ6-1", "url": "https://www.uniprot.org/uniprotkb/E7EXN1/entry#A0AC58HRJ6-1", "sequence": { "sequence": "MSAIIATPCNMNCINNNLAGRIADLFNHNEADDLKDKKDKFKSKLFQKKIERIFDHGYQNHDSPGNASTLYRCGLCLKLLTKETERKIPCVPNKINIDARGNIVFTHSRHKAWEVHEYVNCLYEELKSWVQVYWRIWGTINFLTCSRCKQAFLCTELGQCRYHPEAVVYPGIGADHRWHGLGVYPCCNQKVLRFDPSFMPKGCKIRDHIVSAADGGDCSDHNVNSTQTRILNDLLLHRDAVCVAESSEDLSVGSENVPGCDVMLEPGVLTAHRPKETTAFSLLKNWSLQLRQQSLLSEDEEYTTGSEVTEDEVGDEEDTSKKQAAKKARKSGKPLKRQVSSPNFHRKEKSGEKAPSRDTTPFTVSIQKNKWDSNRSMRYNQDAQREEDQRRMEEIIANLTKMRFGDQEQTKFKDTKEPAGGLYSRLEAQFKASSQSSARQSSSEKTLRAKTRSGPSRPT", "length": 459, "header": "tr|A0AC58HRJ6-1|A0AC58HRJ6_DANRE Computationally mapped isoform of SANT and BTB domain regulator of class switch recombination isoform X3 OS=Danio rerio OX=7955 GN=sanbr PE=4 SV=1 CANONICAL=E7EXN1-1" }, "locus": {} }, { "isoform_ac": "A0AC58HRK1-1", "url": "https://www.uniprot.org/uniprotkb/E7EXN1/entry#A0AC58HRK1-1", "sequence": { "sequence": "MNRLCSVNNNFPYDNNLLVLDIVLSSLWASPQPINWENVAKLVPGFTPKECARRFEELKTTGSFPHVDEQCNPLTGAVSSPSESFSTYIKSNVLDITRDTGEPQSNQTTLSVSGLNVLPTGRGASIETEIADPAKNIEKTEENKSPNMVIHVCDEAKNLKQDFVCPRNLLVKEMRYFEEYLSVDPQRWDEVDISVHCDVQIFDWLMNYAKSHNTEQSHGKHTEKPKLEHSNVISILISSEFLKMETLVEECIQYCHKHMSAIIATPCNMNCINNNLAGRIADLFNHNEADDLKDKKDKFKSKLFQKKIERIFDHGYQNHDSPGNASTLYRCGLCLKLLTKETERKIPCVPNKINIDARGNIVFTHSRHKAWEVHEYVNCLYEELKSWVQVYWRIWGTINFLTCSRCKQAFLCTELGQCRYHPEAVVYPGIGADHRWHGLGVYPCCNQKVLRFDPSFMPKGCKIRDHIVSAADGGDCSDHNVNSTQTRILNDLLLHRDAVCVAESSEDLSVGSENVPGCDVMLEPGVLTAHRPKETTAFSLLKNWSLQLRQQSLLSEDEEYTTGSEVTEDEVGDEEDTSKKQAAKKARKSGKPLKRQVSSPNFHRKEKSGEKAPSRDTTPFTVSIQKNKWDSNRSMRYNQDAQREEDQRRMEEIIANLTKMRFGDQEQTKFKDTKEPAGGLYSRLEAQFKASSQSSARQSSSEKTLRAKTRSGPSRPT", "length": 717, "header": "tr|A0AC58HRK1-1|A0AC58HRK1_DANRE Computationally mapped isoform of SANT and BTB domain regulator of class switch recombination isoform X2 OS=Danio rerio OX=7955 GN=sanbr PE=4 SV=1 CANONICAL=E7EXN1-1" }, "locus": {} }, { "isoform_ac": "E7EXN1-1", "url": "https://www.uniprot.org/uniprotkb/E7EXN1/entry#E7EXN1-1", "sequence": { "sequence": "MKEEHCFQRKPRIHLEQEMNRLCSVNNNFPYDNNLLVLDIVLSSLWASPQPINWENVAKLVPGFTPKECARRFEELKTTGSFPHVDEQCNPLTGAVSSPSESFSTYIKSNVLDITRDTGEPQSNQTTLSVSGLNVLPTGRGASIETEIADPAKNIEKTEENKSPNMVIHVCDEAKNLKQDFVCPRNLLVKEMRYFEEYLSVDPQRWDEVDISVHCDVQIFDWLMNYAKSHNTEQSHGKHTEKPKLEHSNVISILISSEFLKMETLVEECIQYCHKHMSAIIATPCNMNCINNNLAGRIADLFNHNEADDLKDKKDKFKSKLFQKKIERIFDHGYQNHDSPGNASTLYRCGLCLKLLTKETERKIPCVPNKINIDARGNIVFTHSRHKAWEVHEYVNCLYEELKSWVQVYWRIWGTINFLTCSRCKQAFLCTELGQCRYHPEAVVYPGIGADHRWHGLGVYPCCNQKVLRFDPSFMPKGCKIRDHIVSAADGGDCSDHNVNSTQTRILNDLLLHRDAVCVAESSEDLSVGSENVPGCDVMLEPGVLTAHRPKETTAFSLLKNWSLQLRQQSLLSEDEEYTTGSEVTEDEVGDEEDTSKKQAAKKARKSGKPLKRQVSSPNFHRKEKSGEKAPSRDTTPFTVSIQKNKWDSNRSMRYNQDAQREEDQRRMEEIIANLTKMRFGDQEQTKFKDTKEPAGGLYSRLEAQFKASSQSSARQSSSEKTLRAKTRSGPSRPT", "length": 735, "header": "tr|E7EXN1-1|E7EXN1_DANRE Isoform 1 of SANT and BTB domain regulator of class switch recombination isoform X1 OS=Danio rerio OX=7955 GN=sanbr PE=4 SV=1 CANONICAL=E7EXN1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:793832", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:793832", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MFY0-1", "protein_name": "Uncharacterized protein KIAA1841 homolog isoform X3", "gene_name": "Kiaa1841", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSRGYPENNNFLNNNNQMVLDMILYPLIGIPQTINWETVARLVPGLTPKECAKRFDELKSSGSSPVDNQYNPLMAAGEGPVESLATYIKSSLLETQGDFQENPVDEDTVLKPGRHSIASTRNCSSESENCTTRNAGEKTEESEGPNMVIHVCDEAKNLKEDFICPRDLLVSEMKYFAEYLSMDAQRWEEVDISVHCDVHIFNWLIKYVKRNTKENKDCEIPTLEPGNVISILISSEFLKMDSLVEQCIQYCHRNMNAIVAAPCNMNCINANLLTRIADLFTHNEIDDLKDKKDKFRSKLFCKKIERLFDAEYVNPDSRNNAATLYRCCLCKKLLTRETERRIPCIPGKINVDRHGNIIYIHIRDKTWDVHEYLNSLFEELKSWRDVYWRLWGTINWLTCSRCYQAFLCIEFSHCQYHSEVVVYSTTISSLSTVGTGIYPCCNQKVLRFDPTQLTKGCKVRDHMVILHDQGENDDLLSCPATRILDDLHKHRDVIVTPFLKDAVSDSGLGSCDEKGLEYDILLEPNTPWGPKTGELNAFLSLKNWTLQLKQQSLFSEEEEYTTGSEVTEDEVGDEEEVTKKQRKKEKPKKFTKQPKKQLSSPCSQKKEKAPEKSTSRDMSPFVVSVQKNKWDASRSLRFNQDAQREDDQRRMSEITGHLIKMRLGDLDRVKSKESKEFAGGIYSRLEAQVKASAPGSARQNSSDKNPRSKSRFGQGRPA", "length": 718 }, "evidence": [ { "id": "E7EXN1", "url": "https://omabrowser.org/oma/group/E7EXN1/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A1A5R8-1", "protein_name": "SANT and BTB domain regulator of class switch recombination", "gene_name": "Sanbr", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSRGCPENNNFLTNNNQMVLDMILYPLIGIPQTINWETVARLVPGLTPKECVKRFDELKSCGSSPVDNQYNPLMAAGEGPVETLATYIKSSLLDAQGDFQETPVDQDTVSKAGRHSIATTRNCSSESENCTARNAGEETGDSEGPNMVIHVCDEAKSLKEDFICPRDLLISEMKYFAEYLSVDAQRWEEVDISVHCDVHIFNWLIKYVKRNTKDSKDCELPALEPGNVISILISSEFLKMDSLVEQCIQYCHKNMNAIVAAPCNMNCINVNLLTRIADLFTHNEIDDLKDKKDKFRSKLFCKKIERLFDPEYFNPDSRNNAATLYRCCLCKKLLTRETERRISCIPGKINVDRHGNIIYIHIRDKTWDVHEYLNSLFEELKSWRDVYWRLWGTINWLTCSRCYQAFLCIEFSHCQYHSEVVVYSSAVNSLNTVGTGIYPCCNQKVLRFDPTQLTKGCKVRDHMVLLHDQGENDDSLSCPTAKILDDLHKHKDVIAVPFLKDPVSDPGVGSCDEKGLEYEILLEPNTPWGSKTGELNAFLSLKNWTLQLKQQSLFSEEEEYTTGSEVTEDEVGDEEEISKKQRKKEKPKKFTKPPKKQLSSPCSQKKEKTLEKSTSRDVSPFVVSMQKNKWDATRSLRFNQDAQREDDQRRMSEITGHLIKMRLGDLDRVKAKESKEFAGGIYSRLEAQVKASVPVTARQNSSDKNQSNIPQRHLFNYVHSNFIRNSQKLETSQMFIN", "length": 737 }, "evidence": [ { "id": "HGNC:29387", "url": "https://alliancegenome.org/gene/HGNC:29387#orthology", "database": "AGR" }, { "id": "MGI:1918925", "url": "https://alliancegenome.org/gene/MGI:1918925#orthology", "database": "AGR" }, { "id": "E7EXN1", "url": "https://omabrowser.org/oma/group/E7EXN1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q68FF0-1", "protein_name": "SANT and BTB domain regulator of class switch recombination", "gene_name": "Sanbr", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSRGYPENNNFLNNNNQMVLDMILYPLIGIPQTINWETVARLVPGLTPKECVKRFDELKSCGSSPVDNQYNPLMATGEGPVETLATYIKSSLLDTQGDFQETPVDQDTVSKAGRHSIATTRNCSSESENCTARNAGEETGESEGPNMVIHVCDEAKSLKEDFICPRDLLISEMKYFAEYLSMDAQRWEEVDISVHCDVHIFNWLIKYVKRNTKESKDCEIPALEPGNVISILISSEFLKMDSLVEQCIQYCHKNMNAIVAAPCNMNCINANLLTRIADLFTHNEIDDLKDKKDKFRSKLFCKKIERLFDPEYSNPDSRNNAATLYRCCLCKKLLTRETERRIPCIPGKINVDRHGNIIYIHIRDKTWDVHEYLNSLFEELKSWRDVYWRLWGTVNWLTCSRCYQAFLCIEFSHCQYHSEVVVYSSTVNSLNTVGTGIYPCCNQKVLRFDPTQLTKGCKVRDHMVVLHDQGENDDSPSCPPAKILDDLHKHKDVIAVPFLKDAVSDPGVGSCDEKGLEYEILLEPNTPWGSKTGELNAFLSLKNWTLQLKQQSLFSEEEEYTTGSEVTEDEVGDEEEIAKKQRKKEKPKKFTKPPKKQLSSPCSQKKEKTLEKSTSRDVSPFVVSMQKNKWDASRSLRFNQDAQREDDQRRMSEITGHLIKMRLGDLDRVKAKESKEFAGGIYSRLEAQVRASVPVTARQNSSDKNQRSKSRFGQGRPA", "length": 718 }, "evidence": [ { "id": "HGNC:29387", "url": "https://alliancegenome.org/gene/HGNC:29387#orthology", "database": "AGR" }, { "id": "MGI:1918925", "url": "https://alliancegenome.org/gene/MGI:1918925#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100405-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100405-5#orthology", "database": "AGR" }, { "id": "E7EXN1", "url": "https://omabrowser.org/oma/group/E7EXN1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6NSI8-1", "protein_name": "SANT and BTB domain regulator of class switch recombination", "gene_name": "SANBR", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSRGYSENNNFLNNNNQMVLDMILYPLIGIPQTINWETIARLVPGLTPKECAKRFDELKSSGSSPVDNQYNSLMAAGESPVETLATYIKSSLLDIHGEFQETPVGHDAVSKTGRHSIASTRNCSSESENCTTHNGGEMTEESEGPNMVIHVCDEAKNLKEDFTCPRDLLISEMKYFAEYLSMDAQRWEEVDISVHCDVHIFNWLIKYIKRNTKENKDCEMPTLEPGNVISILISSEFLKMDSLVEQCIQYCHKNMNAIVATPCNMNCINANLLTRIADLFSHNEVDDLKDKKDKFKSKLFCKKIERLFDPEYLNPDSRSNAATLYRCCLCKKLLTKETERRIPCIPGKINVDRRGNIVYIHIRDKTWDVHEYLNSLFEELKSWRDVYWRLWGTINWLTCSRCYQAFLCIEFSHCQYHSETVVYPTAASSLNTVGTGIYPCCNQKVLRFDPTQLTKGCKVRDHMVTLRDQGEGGDLPSCPTARMLDDLHKYRDVIVVPFSKDTVSDVGVGLCDEKGIECDVLLEPNTPWGPKTGELNAFLSLKNWTLQLKQQSLFSEEEEYTTGSEVTEDEVGDEEEVSKKQRKKEKPKKFTRQPKKQVSSPCAQRKEKALEKSASRDVSPFVMSMQKNKWDATRSLRFNQDAQREDDQRRMTEITGHLIKMRLGDLDRVKSKEAKEFAGGIYSRLEAQIKASVPVSARQSSSEKNTRSKSRFGQGRPA", "length": 718 }, "evidence": [ { "id": "HGNC:29387", "url": "https://alliancegenome.org/gene/HGNC:29387#orthology", "database": "AGR" }, { "id": "MGI:1918925", "url": "https://alliancegenome.org/gene/MGI:1918925#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100405-5", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100405-5#orthology", "database": "AGR" }, { "id": "E7EXN1", "url": "https://omabrowser.org/oma/group/E7EXN1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VT34-1", "protein_name": "SANT and BTB domain-containing protein", "gene_name": "Dmel\\CG6761", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MQKSGSDEGASAAGQPEETPAAPSQKSIDSGNGAEFQITLNEFLEFLKLSCHVNDMITKADMGKPHNREPIPPMEGSAVSTKRATKKDEFDFAELADNPLVNELLGLRRPSRSSNESRSSLLQDAKSSTLRSGHSHHGRSSRPESTYRGLHPKLGEQLDAAINEGVLDSVLSFICPVPMPTQLQNGKTKPKQLQPPKELLTQTSATTTPYTNPIPAAAPLTSGASKSMMEIGHSHGPLPAATPSAPCLQQAHPGGDALHSDQITNSMVRAMIKEPIPKPGAMNAGRRKSLLLVKDSKHARQERKEPEVVIHVCDEVKNTSKDFTCPQHLLVTKMGYFADVTAGQRLEEMDISVHCDILIFDWLMKWIKHSAQSQDLPVPTQSTGPQLDGNNVVPILVSASFLQMEPLLLECLAFCHAHLSEVVRTSTNLSCLNDALVSRLAAMFTNLELEMVRDKKERVTPRLWTKLIQSLCEPDPEALRGHFYSMSGLFRCSRCFNCVTNTMKSYVSCVPSNIRLNRWGQLMSHHVRDTNWDLNVYIVQLFKELKSWRKVYWKLWGHCHYLYCCSCEAHFPVYQMHWCRFHPEAPNFLGPVGNAGPAGRFSCCGQQAFRYETLPGPNGCQFREHSVLVETDRERAILAIAQLVGENYALCEQPPLRIQELAAAGEISPSWQGISLTPQRCRQGLLPQLCMDSVLKRVTNHRVSRRMRGSRYQMDTSTDSETTSTSEDDARCLRPRMRNVHDDDEDYSTSSDGCESEHRPPPRKTRGKKSRKRPTDVSGRFWSGELSARSNQDHQRDFEEKIMKQVANYVTKKTGTDQCLVQNAQPLGGSYVRLESEWKEMLKQRHSHHTIQGTNATGTSVAQSNSSCLGSALATGGSSVSVMSKQKHK", "length": 889 }, "evidence": [ { "id": "HGNC:29387", "url": "https://alliancegenome.org/gene/HGNC:29387#orthology", "database": "AGR" }, { "id": "MGI:1918925", "url": "https://alliancegenome.org/gene/MGI:1918925#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "isotype switching", "id": "GO:0045190", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045190", "evidence": [ { "database": "UniProtKB", "id": "E7EXN1", "url": "https://www.uniprot.org/uniprotkb/E7EXN1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 161, "end_pos": 163, "annotation": "n_glycosylation_sequon" }, { "start_pos": 342, "end_pos": 344, "annotation": "n_glycosylation_sequon" }, { "start_pos": 500, "end_pos": 502, "annotation": "n_glycosylation_sequon" }, { "start_pos": 561, "end_pos": 563, "annotation": "n_glycosylation_sequon" }, { "start_pos": 650, "end_pos": 652, "annotation": "n_glycosylation_sequon" }, { "start_pos": 674, "end_pos": 676, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EXN1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXN1" }, { "id": "PF11822", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF11822" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SANT and BTB", "eco_id": "ECO_0000259", "start_pos": 166, "end_pos": 270, "start_aa": "Met", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 161, "end_pos": 163 }, { "start_pos": 342, "end_pos": 344 }, { "start_pos": 500, "end_pos": 502 }, { "start_pos": 561, "end_pos": 563 }, { "start_pos": 650, "end_pos": 652 }, { "start_pos": 674, "end_pos": 676 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EXP5-1", "uniprot_ac": "E7EXP5", "uniprot_id": "E7EXP5_DANRE", "mass": { "chemical_mass": 41334.0, "monoisotopic_mass": 41334.0 }, "refseq": { "ac": "NP_001373642", "name": "leucine rich repeat containing 75Bb", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373642" }, "gene_names": [ { "name": "lrrc75bb", "type": "recommended", "evidence": [ { "id": "E7EXP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXP5" } ] }, { "name": "gb:eh448937", "type": "synonym", "evidence": [ { "id": "NP_001373642", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373642" }, { "id": "E7EXP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXP5" } ] }, { "name": "lrrc75bb", "type": "synonym", "evidence": [ { "id": "NP_001373642", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373642" } ] } ], "protein_names": [ { "name": "Leucine rich repeat containing 75Bb", "type": "synonym", "evidence": [ { "id": "E7EXP5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXP5/entry#names_and_taxonomy" } ] }, { "name": "fam211bb", "type": "synonym", "evidence": [ { "id": "NP_001373642", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373642" } ] }, { "name": "fam211b", "type": "synonym", "evidence": [ { "id": "NP_001373642", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373642" } ] }, { "name": "leucine rich repeat containing 75Bb", "type": "synonym", "evidence": [ { "id": "NP_001373642", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373642" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01024223.1, EH457108.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000010.1. On Aug 31, 2020 this sequence version replaced XP_001923259.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001373642", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373642" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EXP5", "url": "https://www.uniprot.org/uniprotkb/E7EXP5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "lrrc75bb", "url": "https://www.uniprot.org/uniprotkb/E7EXP5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110721-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110721-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100148888", "url": "https://www.ncbi.nlm.nih.gov/gene/100148888", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR032675", "url": "https://www.ebi.ac.uk/interpro/entry/IPR032675", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100148888", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148888", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7EXP5", "url": "https://www.orthodb.org/?gene=E7EXP5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR39654", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39654", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR39654:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR39654:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001373642", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373642", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58GIL0", "url": "https://www.uniprot.org/uniprotkb/A0AC58GIL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GIL0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GIL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EXP5", "url": "https://www.uniprot.org/uniprotkb/E7EXP5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EXP5-1", "url": "https://www.uniprot.org/uniprotkb/E7EXP5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-110721-3", "url": "https://zfin.org/ZDB-GENE-110721-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGSKLTRQSSLDSQASFFRRGRQDHEERRTGGRGDFLFSSLMLRSDKLPGVLRRSSPCPYVRRVAWVREIQTLLKEQKLEQAIDVLKLLRKDLGLEGTSLNDILYKNAAFLNLVDPISHELLLNLARDLQCPKREADALKSSEKICRQLIYHLTPHSKWSRQNVPRRKTQACLKTTLKKKLANDTVDLSGIPLSGRDLHRVAYYLQNNGSSVTAVDISFTELHDESLRLLLPYLGVLPKLSTLAINGNRLTVAILKDLIEVVKDPQKFPCLAWVDLGNNVDIFTVPQPLLVALRRRFGMRSSLPTIYEYSEGQGSSYCLETSVEEISVFEEEEEDEEDELEDHLVLEAWSVEEKNTLHFCER", "length": 362, "header": "tr|E7EXP5-1|E7EXP5_DANRE Isoform 1 of Leucine rich repeat containing 75Bb OS=Danio rerio OX=7955 GN=lrrc75bb PE=4 SV=1 CANONICAL=E7EXP5-1" }, "isoforms": [ { "isoform_ac": "A0AC58GIL0-1", "url": "https://www.uniprot.org/uniprotkb/E7EXP5/entry#A0AC58GIL0-1", "sequence": { "sequence": "MEEEIHPDVQHLKTTLKKKLANDTVDLSGIPLSGRDLHRVAYYLQNNGSSVTAVDISFTELHDESLRLLLPYLGVLPKLSTLAINGNRLTVAILKDLIEVVKDPQKFPCLAWVDLGNNVDIFTVPQPLLVALRRRFGMRSSLPTIYEYSEGQGSSYCLETSVEEISVFEEEEEDEEDELEDHLVLEAWSVEEKNTLHFCER", "length": 201, "header": "tr|A0AC58GIL0-1|A0AC58GIL0_DANRE Computationally mapped isoform of Leucine rich repeat containing 75Bb isoform X1 OS=Danio rerio OX=7955 GN=lrrc75bb PE=4 SV=1 CANONICAL=E7EXP5-1" }, "locus": {} }, { "isoform_ac": "E7EXP5-1", "url": "https://www.uniprot.org/uniprotkb/E7EXP5/entry#E7EXP5-1", "sequence": { "sequence": "MGSKLTRQSSLDSQASFFRRGRQDHEERRTGGRGDFLFSSLMLRSDKLPGVLRRSSPCPYVRRVAWVREIQTLLKEQKLEQAIDVLKLLRKDLGLEGTSLNDILYKNAAFLNLVDPISHELLLNLARDLQCPKREADALKSSEKICRQLIYHLTPHSKWSRQNVPRRKTQACLKTTLKKKLANDTVDLSGIPLSGRDLHRVAYYLQNNGSSVTAVDISFTELHDESLRLLLPYLGVLPKLSTLAINGNRLTVAILKDLIEVVKDPQKFPCLAWVDLGNNVDIFTVPQPLLVALRRRFGMRSSLPTIYEYSEGQGSSYCLETSVEEISVFEEEEEDEEDELEDHLVLEAWSVEEKNTLHFCER", "length": 362, "header": "tr|E7EXP5-1|E7EXP5_DANRE Isoform 1 of Leucine rich repeat containing 75Bb OS=Danio rerio OX=7955 GN=lrrc75bb PE=4 SV=1 CANONICAL=E7EXP5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "E7EXP5", "url": "https://www.uniprot.org/uniprotkb/E7EXP5" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:100148888", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148888", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0M1Z9-1", "protein_name": "Leucine rich repeat containing 75B", "gene_name": "Lrrc75b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGARLGRRARADAPAAPSAGPAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLEGNLLTDILYRNVTFLNLVDPISHDLLVNLARDLQCPKKDHELWKSSDKICRQLIYHLTPHSKRKPHRKTQSSLKSSLQKTLLVGETVDLSGIPLSARDVQHISRYLDSRGVELVVLDLSFTELSDDLLHLLLPSLWALPRLTQLLLNGNRLTRAAARELTEAIKDATKFPVLAWVDLGNNVDVSSLPQPLLVGLRRRLSQHTSLPTIYEGLDLEPGGGMAETTAAVSTWGSAATEAGPEPQGCCAR", "length": 306 }, "evidence": [ { "id": "MGI:2143657", "url": "https://alliancegenome.org/gene/MGI:2143657#orthology", "database": "AGR" }, { "id": "HGNC:33155", "url": "https://alliancegenome.org/gene/HGNC:33155#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F1QJF5-1", "protein_name": "Leucine-rich repeat-containing protein 75B isoform X1", "gene_name": "lrrc75ba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGSRLSRQNSLDNENFSRRRRKHLDSTGESDRGGDFLFTSLMLRSDKLPGMLRRSNHSPYVRRVAWIREMQKLLRERKIEEATDVLKLLRKDLGLEGTSLNDILYKNAAFLNLVDPISHELLLSLARDMQCPKKDLETLKSSDKICRQLIYHLTPHSKWLRKSMTRRKAQACLKTTLQKKLCSDSVDLSGIPLSTRDIRHVAYYLQTSGGAVISVDLSFTELRDEGLRLLLPFLGALPKLTTLALNGNRLTLGILKDLSEAFKESKRFSCLAWIDLGNNVDIFTMPQPLLVALRRRCSLKSSLPTIYEYTEGQPYCYRMESSIEEPSHYEEEEDEDYDEDLEPWSIGEQKSSGSFTLHHCER", "length": 362 }, "evidence": [ { "id": "MGI:2143657", "url": "https://alliancegenome.org/gene/MGI:2143657#orthology", "database": "AGR" }, { "id": "HGNC:33155", "url": "https://alliancegenome.org/gene/HGNC:33155#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q2VPJ9-1", "protein_name": "Leucine-rich repeat-containing protein 75B", "gene_name": "LRRC75B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGARLGRRAGPEAGSEAGAAAGCGPAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLERTLLPDILYRDVAFLNPVDPISHDLLVNLARDLQCPKKDYELWKSSDKICRQLIYHLTPHSKQQQGSSLRQRKTQSCLKSSLQKTLLAGETVDLSGIPLSTQDVQHITRYLSSHGAVLAVLDLSFTGLSDELLHLLLPSLWALPRLTQLLLNGNRLTRATARKLTDAIKDTTKFPALAWVDLGNNVDVASLPQPLLVGLRRRLSQRTSLPTIYEGLDLEPEGSAAGATTPASTWDSTAAGLGPEPQACCAR", "length": 315 }, "evidence": [ { "id": "MGI:2143657", "url": "https://alliancegenome.org/gene/MGI:2143657#orthology", "database": "AGR" }, { "id": "HGNC:33155", "url": "https://alliancegenome.org/gene/HGNC:33155#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110721-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110721-3#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q7TPD7-1", "protein_name": "Leucine-rich repeat-containing protein 75B", "gene_name": "Lrrc75b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGARLGRRARADAPAAPSAGPAPYERRVRWLREIQSTLRERRPERARQLLRLLRQDLGLEGNLLTDILHRNVTFLNLVDPISHDLLVNLARDLQCPKKDHELWKSSDKICRQLIYHLTPHSKRKHHRKTQSSLKSSLQKTLLVGETVDLSGIPLSARDVQHISRYLDTRGVELVVLDLSFTELSDELLHLLLPSLWALPRLTQLLLNGNRLTRAAARELTEAIKDTAKFPVLAWVDLGNNVDVSSLPQPLLVGLRRRLSQHTSLPTIYEGLDLEPGGGMAETTAAVSTWGSAATEAGPEPQGCCAR", "length": 306 }, "evidence": [ { "id": "MGI:2143657", "url": "https://alliancegenome.org/gene/MGI:2143657#orthology", "database": "AGR" }, { "id": "HGNC:33155", "url": "https://alliancegenome.org/gene/HGNC:33155#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110721-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110721-3#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 208, "end_pos": 210, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 208, "end_pos": 210 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7EXT9-1", "uniprot_ac": "E7EXT9", "uniprot_id": "E7EXT9_DANRE", "mass": { "chemical_mass": 35444.0, "monoisotopic_mass": 35444.0 }, "refseq": { "ac": "XP_003200952", "name": "cyclin-I isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200952" }, "gene_names": [ { "name": "ccni2", "type": "recommended", "evidence": [ { "id": "E7EXT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXT9" } ] }, { "name": "ccni2", "type": "synonym", "evidence": [ { "id": "XP_003200952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200952" } ] } ], "protein_names": [ { "name": "Cyclin-I isoform X1", "type": "synonym", "evidence": [ { "id": "E7EXT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXT9/entry#names_and_taxonomy" } ] }, { "name": "cyclin-I isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003200952", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200952" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003200952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200952" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EXT9", "url": "https://www.uniprot.org/uniprotkb/E7EXT9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ccni2", "url": "https://www.uniprot.org/uniprotkb/E7EXT9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-081106-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081106-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000033046", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000033046", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100330479", "url": "https://www.ncbi.nlm.nih.gov/gene/100330479", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039361", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039361", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100330479", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330479", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PQRDEIC", "url": "https://omabrowser.org/oma/group/PQRDEIC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EXT9", "url": "https://www.orthodb.org/?gene=E7EXT9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR10177", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR10177", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003200952", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200952", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58IBN6", "url": "https://www.uniprot.org/uniprotkb/A0AC58IBN6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58IBN6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58IBN6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EXT9", "url": "https://www.uniprot.org/uniprotkb/E7EXT9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EXT9-1", "url": "https://www.uniprot.org/uniprotkb/E7EXT9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-081106-2", "url": "https://zfin.org/ZDB-GENE-081106-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKLPGEEENQRLGTLLLNTLDREMRLWRAPVLKNGCIQGSDISPSQYHEVILWLREMNVIFQFSTETLALGVCVLNSLLATVKTQLKYLKCMAITSLILAAKINEEDEVIASVKDLLEQSRCKFSTAEILRMERVILHKLHWELYLATPMDFIHIFHGLLMSGCVDQTQKRLCLQAALWSRQLQHCMACHQLWQFKGSILALAIITLELERLTPDWFSVFTGLLRKAQIESTELICCRETVDEYLSSLRFSIPTNAVYILGSGVLVLRGPEGEQRKRQARRAHTAQDMDDFYDGFCCLYDEQTSACPALI", "length": 310, "header": "tr|E7EXT9-1|E7EXT9_DANRE Isoform 1 of Cyclin-I isoform X1 OS=Danio rerio OX=7955 GN=ccni2 PE=3 SV=2 CANONICAL=E7EXT9-1" }, "isoforms": [ { "isoform_ac": "A0AC58IBN6-1", "url": "https://www.uniprot.org/uniprotkb/E7EXT9/entry#A0AC58IBN6-1", "sequence": { "sequence": "MKLPGEEENQRLGTLLLNTLDREMRLWRAPVLKNGCIQGSDISPSQYHEVILWLREMNVIFQFSTETLALGVCVLNSLLATVKTQLKYLKCMAITSLILAAKINEEDEVIASVKDLLEQSRCKFSTAEILRMERVILHKLHWELYLATPMDFIHIFHGLLMSGCVDQTQKRLCLQAALWSRQLQHCMACHQLWQFKGSILALAIITLELERLTPDWFSVFTGLLRKAQVVKRIH", "length": 234, "header": "tr|A0AC58IBN6-1|A0AC58IBN6_DANRE Computationally mapped isoform of Cyclin-I isoform X2 OS=Danio rerio OX=7955 GN=ccni2 PE=3 SV=1 CANONICAL=E7EXT9-1" }, "locus": {} }, { "isoform_ac": "E7EXT9-1", "url": "https://www.uniprot.org/uniprotkb/E7EXT9/entry#E7EXT9-1", "sequence": { "sequence": "MKLPGEEENQRLGTLLLNTLDREMRLWRAPVLKNGCIQGSDISPSQYHEVILWLREMNVIFQFSTETLALGVCVLNSLLATVKTQLKYLKCMAITSLILAAKINEEDEVIASVKDLLEQSRCKFSTAEILRMERVILHKLHWELYLATPMDFIHIFHGLLMSGCVDQTQKRLCLQAALWSRQLQHCMACHQLWQFKGSILALAIITLELERLTPDWFSVFTGLLRKAQIESTELICCRETVDEYLSSLRFSIPTNAVYILGSGVLVLRGPEGEQRKRQARRAHTAQDMDDFYDGFCCLYDEQTSACPALI", "length": 310, "header": "tr|E7EXT9-1|E7EXT9_DANRE Isoform 1 of Cyclin-I isoform X1 OS=Danio rerio OX=7955 GN=ccni2 PE=3 SV=2 CANONICAL=E7EXT9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100330479", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100330479", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D4A5E4-1", "protein_name": "Cyclin-I", "gene_name": "Ccni", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKFPGPLENQRLSSLLERAISREAQMWKVNVPKIPTNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLNCIAISCFFLAAKTVEEDEKIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQLLFSLPRLSPSQHLAVLTKQLLHCMACNQLLQFKGSMLALAMVSLEMEKLIPDWLPLTIELLQKAQMDSSQLIHCRELVAYHLSALQSSLPLNSVYVYRPLKHTLVTCDKGAFKLHPSSISGPDFSKDNSKPEVPVRGPAAFHLHLPAVSGCKHTSAKRKVEEMEVDDLYDGIKRLYNEDSGSENVGSVCGTDLSRQEGHASPCPPLQPVSVM", "length": 377 }, "evidence": [ { "id": "FB:FBgn0039858", "url": "https://alliancegenome.org/gene/FB:FBgn0039858#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1BC90-1", "protein_name": "Cyclin-G1", "gene_name": "CCNI2", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MASGGRHAPQNSASEVRPSRCPGKSSDESLGEMALRCPLPPRPWNVSLSAAIQRSFSEACLRDALRFPAPPSWTRSVRGGMRARPPAGPDPAAARGPSPAPSTQPPVPSAPRLMQKTWGGFPDQRRLLAYLTQAQGREARLWRGGQLQQAEICEAFREVVLWLLRVENIFDFSQTTFNLALSIFSRLIVSVKIKKHLLHCVTITSLRLATKVNEEEELIPRIKDFIKHYGSGYSPNELLRMELAILDKLHWDLYIGTPLDFLSIFHALVVLGWPHVKELMPQRNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPDCCTPISDLLKKAQVGIRQWNRCKELVKEQLASL", "length": 361 }, "evidence": [ { "id": "E7EXT9", "url": "https://omabrowser.org/oma/group/E7EXT9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "O08918-1", "protein_name": "Cyclin-G2", "gene_name": "Ccng2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKDLGAKHLAGGEGVQLFGLLNFYLEQEQRYQPREKGLILMEATPENDNTLCSRLRNAKVEDLRSLTNFFGSGTETFVLAVNILDRFLALMKVKPKHLSCIGVCCFLLAARLAEEEGDVPPTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHAIVFCHTSERKEILSLDKLEAQLKACNCRVVFSKARPSVLALCLLNLEIETIKSVELLEILLLVKKHLKLSDTEFFYWRELVSKCLAEYSSPRCCKPDLKKLVWIVSRRTAQNLHSSYYSVPELPTIPEGGCFDGSESEDSGEDMSCGEESLSSSPPSDQECTFFFDFQVAQTLCFPP", "length": 344 }, "evidence": [ { "id": "FB:FBgn0039858", "url": "https://alliancegenome.org/gene/FB:FBgn0039858#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P39950-1", "protein_name": "Cyclin-G1", "gene_name": "Ccng1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MIEVLTTDSQKLLHQLNTLLEQESRCQPKVCGLKLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQAKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLIRETLPFERRNDLNFERLEAQLKACHCRIIFSKAKPSVLALAIIALEIQALKYVELTEGVECIQKHSKISGRDLTFWQELVSKCLTEYSSNKCSKPNGQKLKWIVSGRTARQLKHSYYRITHLPTIPETMG", "length": 294 }, "evidence": [ { "id": "FB:FBgn0039858", "url": "https://alliancegenome.org/gene/FB:FBgn0039858#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P51945-1", "protein_name": "Cyclin-G1", "gene_name": "Ccng1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIEVLTTDSQKLLHQLNTLLEQESRCQPKVCGLKLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQAKHLGCVGLSCFYLAVKATEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLVHDTLPFERRNDLNFERLEAQLKACHCRIIFSKAKPSVLALSILALEIQALKYVELTEGVECIQKHSKISGRDLTFWQELVSKCLTEYSSNKCSKPNGQKLKWIVSGRTARQLKHSYYRITHLPTIPETIC", "length": 294 }, "evidence": [ { "id": "FB:FBgn0039858", "url": "https://alliancegenome.org/gene/FB:FBgn0039858#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P51959-1", "protein_name": "Cyclin-G1", "gene_name": "CCNG1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIEVLTTTDSQKLLHQLNALLEQESRCQPKVCGLRLIESAHDNGLRMTARLRDFEVKDLLSLTQFFGFDTETFSLAVNLLDRFLSKMKVQPKHLGCVGLSCFYLAVKSIEEERNVPLATDLIRISQYRFTVSDLMRMEKIVLEKVCWKVKATTAFQFLQLYYSLLQENLPLERRNSINFERLEAQLKACHCRIIFSKAKPSVLALSIIALEIQAQKCVELTEGIECLQKHSKINGRDLTFWQELVSKCLTEYSSNKCSKPNVQKLKWIVSGRTARQLKHSYYRITHLPTIPEMVP", "length": 295 }, "evidence": [ { "id": "FB:FBgn0039858", "url": "https://alliancegenome.org/gene/FB:FBgn0039858#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q14094-1", "protein_name": "Cyclin-I", "gene_name": "CCNI", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKFPGPLENQRLSFLLEKAITREAQMWKVNVRKMPSNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLSCIAISCFFLAAKTVEEDERIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSTRPQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFRGSMLALAMVSLEMEKLIPDWLSLTIELLQKAQMDSSQLIHCRELVAHHLSTLQSSLPLNSVYVYRPLKHTLVTCDKGVFRLHPSSVPGPDFSKDNSKPEVPVRGTAAFYHHLPAASGCKQTSTKRKVEEMEVDDFYDGIKRLYNEDNVSENVGSVCGTDLSRQEGHASPCPPLQPVSVM", "length": 377 }, "evidence": [ { "id": "FB:FBgn0039858", "url": "https://alliancegenome.org/gene/FB:FBgn0039858#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q16589-1", "protein_name": "Cyclin-G2", "gene_name": "CCNG2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKDLGAEHLAGHEGVQLLGLLNVYLEQEERFQPREKGLSLIEATPENDNTLCPGLRNAKVEDLRSLANFFGSCTETFVLAVNILDRFLALMKVKPKHLSCIGVCSFLLAARIVEEDCNIPSTHDVIRISQCKCTASDIKRMEKIISEKLHYELEATTALNFLHLYHTIILCHTSERKEILSLDKLEAQLKACNCRLIFSKAKPSVLALCLLNLEVETLKSVELLEILLLVKKHSKINDTEFFYWRELVSKCLAEYSSPECCKPDLKKLVWIVSRRTAQNLHNSYYSVPELPTIPEGGCFDESESEDSCEDMSCGEESLSSSPPSDQECTFFFNFKVAQTLCFPS", "length": 344 }, "evidence": [ { "id": "FB:FBgn0039858", "url": "https://alliancegenome.org/gene/FB:FBgn0039858#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q6ZMN8-1", "protein_name": "Cyclin-I2", "gene_name": "CCNI2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MASGAQLPPQPSSSEVSAVQSPGGRPGAGLEETALGVPLPPSPGEAPLPRSNRSRCPGTRQPGAASLHAASAAVPVRPRRGTAPAGKTADAVPAAAPEQAPRPAPQSRKPRNLEGDLDERRLLCHLQLAQDREARLWRGGKPQDEICDAFEEVVLWLLRLQNTFYFSQSTFNLALTIFGRLLISVKVKEKYLHCATITSLRLAAKVNEEEEFIPQVKDFTKHYGSDYSPNELLRMELAILDRLHWDLYIGTPLDFLTIFHALVVLSWPHVLELLPQRNPSLHVASLTRQLQHCMAGHQLLQFKGSTLALVIITLELERLMPGWCAPISDLLKKAQVGDMQYSCCKELVMQQLRSLQSSSCTDNFVSPAN", "length": 369 }, "evidence": [ { "id": "HGNC:33869", "url": "https://alliancegenome.org/gene/HGNC:33869#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081106-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081106-2#orthology", "database": "AGR" }, { "id": "FB:FBgn0039858", "url": "https://alliancegenome.org/gene/FB:FBgn0039858#orthology", "database": "AGR" }, { "id": "E7EXT9", "url": "https://omabrowser.org/oma/group/E7EXT9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q95TJ9-1", "protein_name": "Cyclin G", "gene_name": "CycG", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSVPVRYSSAAAEYAAEVDCELESTLQQQQQLHLQQQYEQYQHYQYQREQDIAYYCQLQAARQQEQLMQQRTSMSSSVMPGLALPQDHQDHPAALLNGPHNNNIGLAMDAHSINAILVDDEQPSTSAQAAAAAAASAGGSAGAGSGSGLGGAIGGGKLANGINRNAEMPTDWMRIADEGRYGTPGAAGLEYQKYEQQQQLEDLAESEAGAVGGASNNNGESSSSLKKLEDQLHALTSDELYETLKEYDVLQDKFHTVLLLPKESRREVTAGGRDGSAYVLRCLKMWYELPSDVLFSAMSLVDRFLDRMAVKPKHMACMSVASFHLAIKQLDLKPIPAEDLVTISQCGCTAGDLERMAGVIANKLGVQMGHAPITSVSYLRIYYALFRNLAKEIGGDFFKFYQQLIKLEELENRLEILMCDVKTTVITPSTLALVLICLHLDFHIKESYTRGSPELKHVFEYILFLQQYMRIPDRVFTCGFSIVSGILSHYNGQNKAPYKQRLVWKLSSRTLRVLRPINRFSSDLPTIEEGIPNALDDGLRSRTESISSEEEEDWPTSPIIPIFEQC", "length": 566 }, "evidence": [ { "id": "HGNC:33869", "url": "https://alliancegenome.org/gene/HGNC:33869#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-081106-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-081106-2#orthology", "database": "AGR" }, { "id": "FB:FBgn0039858", "url": "https://alliancegenome.org/gene/FB:FBgn0039858#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Z2V9-1", "protein_name": "Cyclin-I", "gene_name": "Ccni", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKFPGPLENQRLSSLLERAISREAQMWKVNVPKIPTNQNVSPSQRDEVIQWLAKLKYQFNLYPETFALASSLLDRFLATVKAHPKYLNCIAISCFFLAAKTVEEDEKIPVLKVLARDSFCGCSSSEILRMERIILDKLNWDLHTATPLDFLHIFHAIAVSARPQLLFSLPKLSPSQHLAVLTKQLLHCMACNQLLQFKGSMLALAMVSLEMEKLIPDWLPLTIELLQKAQMDSSQLIHCRELVAYHLSALQSALPLNSVYVYRPLKHTLVTCDKGAFKLHPSSVSGPDFSKDNSKPEVPVRGPAAFHLHLPAASGCKQTSAKRKVEEMEVDDFYDGIKRLYNEDNGPENVGSVCGTDLSRQEGHASPCPPLQPVSVM", "length": 377 }, "evidence": [ { "id": "FB:FBgn0039858", "url": "https://alliancegenome.org/gene/FB:FBgn0039858#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7EXT9", "url": "https://www.uniprot.org/uniprotkb/E7EXT9" } ], "pmid": "" }, { "name": "cytoplasm", "id": "GO:0005737", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005737", "evidence": [ { "database": "UniProtKB", "id": "E7EXT9", "url": "https://www.uniprot.org/uniprotkb/E7EXT9" } ], "pmid": "" }, { "name": "cyclin-dependent protein kinase holoenzyme complex", "id": "GO:0000307", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000307", "evidence": [ { "database": "UniProtKB", "id": "E7EXT9", "url": "https://www.uniprot.org/uniprotkb/E7EXT9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "G1/S transition of mitotic cell cycle", "id": "GO:0000082", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000082", "evidence": [ { "database": "UniProtKB", "id": "E7EXT9", "url": "https://www.uniprot.org/uniprotkb/E7EXT9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cyclin-dependent protein serine/threonine kinase regulator activity", "id": "GO:0016538", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016538", "evidence": [ { "database": "UniProtKB", "id": "E7EXT9", "url": "https://www.uniprot.org/uniprotkb/E7EXT9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EXT9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXT9" }, { "id": "SM00385", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-like", "eco_id": "ECO_0000259", "start_pos": 52, "end_pos": 138, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", 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"field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { 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##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133195) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_698143.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_698143", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_698143" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EXU5", "url": "https://www.uniprot.org/uniprotkb/E7EXU5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-121a2.4", "url": "https://www.uniprot.org/uniprotkb/E7EXU5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070705-23", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070705-23", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000028541", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000028541", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "569653", "url": 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"MREVKDDSGPVIMSTDREPPVTAKLLHLMFLSTYWGMQIWVTFISGFVMDNHLNRHTFGFIQSRLFPFYLHIGSACAFFNLTIFAMYHPSNMLDDKEAFQILIFFVCVTVAAVNAQWFGQMTSEIMADMHLIEQACGLGQDIGLSSNREAYAKLCETDPKYKKLSARLWLYHLLSSLCNLCCIICNGYSLYYLAENLTTL", "length": 200, "header": "tr|E7EXU5-1|E7EXU5_DANRE Isoform 1 of Transmembrane protein 205 OS=Danio rerio OX=7955 GN=si:ch211-121a2.4 PE=4 SV=1 CANONICAL=E7EXU5-1" }, "isoforms": [ { "isoform_ac": "E7EXU5-1", "url": "https://www.uniprot.org/uniprotkb/E7EXU5/entry#E7EXU5-1", "sequence": { "sequence": "MREVKDDSGPVIMSTDREPPVTAKLLHLMFLSTYWGMQIWVTFISGFVMDNHLNRHTFGFIQSRLFPFYLHIGSACAFFNLTIFAMYHPSNMLDDKEAFQILIFFVCVTVAAVNAQWFGQMTSEIMADMHLIEQACGLGQDIGLSSNREAYAKLCETDPKYKKLSARLWLYHLLSSLCNLCCIICNGYSLYYLAENLTTL", "length": 200, "header": "tr|E7EXU5-1|E7EXU5_DANRE Isoform 1 of Transmembrane protein 205 OS=Danio rerio OX=7955 GN=si:ch211-121a2.4 PE=4 SV=1 CANONICAL=E7EXU5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:569653", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569653", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7EXU5", "url": "https://www.uniprot.org/uniprotkb/E7EXU5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 196, "end_pos": 198, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EXU5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXU5" }, { "id": "PF13664", "database": 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}, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EXZ1-1", "uniprot_ac": "E7EXZ1", "uniprot_id": "E7EXZ1_DANRE", "mass": { "chemical_mass": 31552.0, "monoisotopic_mass": 31552.0 }, "refseq": { "ac": "XP_003201087", "name": "transmembrane protein 221", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201087" }, "gene_names": [ { "name": "tmem221", "type": "recommended", "evidence": [ { "id": "E7EXZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXZ1" } ] }, { "name": "tmem221", "type": "synonym", "evidence": [ { "id": "XP_003201087", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201087" } ] } ], "protein_names": [ { "name": "Transmembrane protein 221", "type": "synonym", "evidence": [ { "id": "E7EXZ1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EXZ1/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 221", "type": "synonym", "evidence": [ { "id": "XP_003201087", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201087" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003201087", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201087" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EXZ1", "url": "https://www.uniprot.org/uniprotkb/E7EXZ1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmem221", "url": "https://www.uniprot.org/uniprotkb/E7EXZ1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120709-92", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120709-92", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000086661", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000086661", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100537506", "url": "https://www.ncbi.nlm.nih.gov/gene/100537506", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029201", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029201", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053101", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053101", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100537506", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100537506", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CPRMHRT", "url": "https://omabrowser.org/oma/group/CPRMHRT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EXZ1", "url": "https://www.orthodb.org/?gene=E7EXZ1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR36132", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36132", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR36132:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR36132:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15038", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15038", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003201087", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003201087", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EXZ1", "url": "https://www.uniprot.org/uniprotkb/E7EXZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EXZ1-1", "url": "https://www.uniprot.org/uniprotkb/E7EXZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120709-92", "url": "https://zfin.org/ZDB-GENE-120709-92", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTHSYSQRSLVILAFLGILSSIMAVLSVILIFQLQTQQAVIKDSPTFVPKDITAVLLPVSTVLSALSLTLNLSSVVVCLLHSYFATEICRGEPDTQRADWFLMDSRAVRHVTIGLFCLGVSVYLAAMSIYMVLVFEVETGIASVCVLSSGVLVLLLIIIHSLIRAARAAKHYRTDHLHTMYHNNPEQIRTSNLSIMENPRRQHSLANLPSHFINPAHMEPKSQYSTSNGPQAHSSDKDGCSGSGRTHRTLSTESGLFHAQAKPWNGVNSEMRSVLARKATIKDSTLV", "length": 287, "header": "tr|E7EXZ1-1|E7EXZ1_DANRE Isoform 1 of Transmembrane protein 221 OS=Danio rerio OX=7955 GN=tmem221 PE=4 SV=1 CANONICAL=E7EXZ1-1" }, "isoforms": [ { "isoform_ac": "E7EXZ1-1", "url": "https://www.uniprot.org/uniprotkb/E7EXZ1/entry#E7EXZ1-1", "sequence": { "sequence": "MTHSYSQRSLVILAFLGILSSIMAVLSVILIFQLQTQQAVIKDSPTFVPKDITAVLLPVSTVLSALSLTLNLSSVVVCLLHSYFATEICRGEPDTQRADWFLMDSRAVRHVTIGLFCLGVSVYLAAMSIYMVLVFEVETGIASVCVLSSGVLVLLLIIIHSLIRAARAAKHYRTDHLHTMYHNNPEQIRTSNLSIMENPRRQHSLANLPSHFINPAHMEPKSQYSTSNGPQAHSSDKDGCSGSGRTHRTLSTESGLFHAQAKPWNGVNSEMRSVLARKATIKDSTLV", "length": 287, "header": "tr|E7EXZ1-1|E7EXZ1_DANRE Isoform 1 of Transmembrane protein 221 OS=Danio rerio OX=7955 GN=tmem221 PE=4 SV=1 CANONICAL=E7EXZ1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 112, "start_aa": "Thr", "end_pos": 112, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr112", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:100537506", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100537506", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B9L8-1", "protein_name": "Transmembrane protein 221", "gene_name": "TMEM221", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MARSYGGRVLTAMILLGIPAAVLAALGAQLLFQLQAGRAELRGPRIDGLGPELGTGPGLPEDAAGALLPLAAALAALALVLGLTCLLLAALCGHLGAEMARGPGPGRSDWFLYDCRLLRHVALGLFCCGISVYLAALSIYALLLFEIETGAAAASVLGLGALILVAVLTHTLLRAARATRRGLHELSLPQFEDDPVRPAEVSKASSGAQPQQGIHHWTPYSSCPEPGDSLRPTVTATAPATMGGGWESRLPTSHIHRTLSASEGHWEEVTHEMRNILGHRPGGSGKDSTLV", "length": 291 }, "evidence": [ { "id": "E7EXZ1", "url": "https://omabrowser.org/oma/group/E7EXZ1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V1ADT3-1", "protein_name": "Transmembrane protein 221", "gene_name": "TMEM221", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MPSYPQRTLTVLLLFGTLSAAMALLASSLIFQLPAGRTSPGSGPGAVRGALPESAAAVLLPVSAVLAALCLVLNVSCLLLCLLHGYFSTELCRGQPGPERADWFLLDSRTVRHAAIGLFCCGVSVYLTALAIYMLLLFELEAGIASACILSSGIIVLLVTVTHALLRASQLSRRSRSEISHTLYENDSAQHSETPGSNLNNKSTAVPRPRPEIHREFSFPPFLEHKSQLGSPASSNLTSSGSPGAHSEKESYHLPRTHRTLSAESALLQAQGKPWNGVTHEMRNVLARKPGASGKDSTLV", "length": 300 }, "evidence": [ { "id": "E7EXZ1", "url": "https://omabrowser.org/oma/group/E7EXZ1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0ABK0LG23-1", "protein_name": "Transmembrane protein 221", "gene_name": "Tmem221", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGRSYGGRVLAAMTLLGIPAAVLVALAAQLLFQLQAGRAELRGIRTDGLHPELDPDAGLPEAAAGALLPLATALAALAQVLGLGCLLLAALCGHLGAELARGPGPGRSDWFLYDCRLLRHSALGLFCCGVSVYLAALAIYALLLFEIEAGAAAASILGSGALILVAIMTHTLFRAVQATRRGLRELPPPSSEDEPARSSEDSKAGCRAQPQQGTHCQIFYNPSQELGDPPGSMATCITSAVLERASESSLLASHLPQTLRSMGPWDGVTYEMHGMLGHRPPDMGKDATLV", "length": 290 }, "evidence": [ { "id": "MGI:3525074", "url": "https://alliancegenome.org/gene/MGI:3525074#orthology", "database": "AGR" }, { "id": "HGNC:21943", "url": "https://alliancegenome.org/gene/HGNC:21943#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A6NGB7-1", "protein_name": 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"Transmembrane protein 221", "gene_name": "TMEM221", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MARSYGGRVLAAMVLLGIPAAVLAALGAQLLFQLQAGRAELRGPRIDGLGPELGAGPRLPEDAAGALLPLAAALSALALVLGLTCLLLAALCGHLGAEMARGPGSNRSDWFLYDCRLLRHVALGLFCCGVSVYLAALSIYALLLFEIETGAAAASILGLGALVLVAALTHTLLQAARTTRRGVHELSPPHFEDDPVCPAEVSKAGPRAQPQQGTHHWTLYSSFPKLGDSLRPMVTDTAPAVMGGGRESCLPASRMHRTLSASEGRWGEVTHEMRSILGHRPAGSGKDSTLV", "length": 291 }, "evidence": [ { "id": "E7EXZ1", "url": "https://omabrowser.org/oma/group/E7EXZ1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q8K071-1", "protein_name": "Transmembrane protein 221", "gene_name": "Tmem221", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGRSYGGRVLAAMTLLGIPAAVLVALAAQLLFQLQAGRAELRRVRTDGLHPELDPDAGLPEAAAGALLPLATALAALAQVLGLSCLLLAALCGHLGAELARGPGPGRSDWFLYDCRLLRHSALGLFCCGVSVYLAALAIYALLLFEIEAGAAAASILGSGALILVAIMTHTLFRAVQATRRGLRELSPPSFEDEPARPSEDSKSGCRAQPPQDEETETPIGAVTHQGSHF", "length": 230 }, "evidence": [ { "id": "MGI:3525074", "url": "https://alliancegenome.org/gene/MGI:3525074#orthology", "database": "AGR" }, { "id": "HGNC:21943", "url": "https://alliancegenome.org/gene/HGNC:21943#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120709-92", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120709-92#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 192, "end_pos": 194, "annotation": "n_glycosylation_sequon" }, { "start_pos": 71, "end_pos": 73, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 112 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 192, "end_pos": 194 }, { "start_pos": 71, "end_pos": 73 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", 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"publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EY35-1", "uniprot_ac": "E7EY35", "uniprot_id": "E7EY35_DANRE", "mass": { "chemical_mass": 29523.0, "monoisotopic_mass": 29523.0 }, "refseq": { "ac": "NP_001373176", "name": "chymotrypsin-like protease CTRL-1 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373176" }, "gene_names": [ { "name": "si:dkey-238d18.3", "type": "recommended", "evidence": [ { "id": "E7EY35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EY35" } ] }, { "name": "si:dkey-238d18.3", "type": "synonym", "evidence": [ { "id": "NP_001373176", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373176" } ] } ], "protein_names": [ { "name": "Chymotrypsin-like protease CTRL-1 precursor", "type": "synonym", "evidence": [ { "id": "E7EY35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EY35/entry#names_and_taxonomy" } ] }, { "name": "chymotrypsin-like protease CTRL-1 precursor", "type": "synonym", "evidence": [ { "id": "NP_001373176", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373176" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH452904.1, EH448452.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505374 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Aug 15, 2020 this sequence version replaced XP_001336264.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001373176", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373176" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EY35", "url": "https://www.uniprot.org/uniprotkb/E7EY35" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-238d18.3", "url": "https://www.uniprot.org/uniprotkb/E7EY35", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131127-38", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131127-38", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "cd00190", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00190", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "795978", "url": "https://www.ncbi.nlm.nih.gov/gene/795978", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001254", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001254", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001314", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001314", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR009003", "url": "https://www.ebi.ac.uk/interpro/entry/IPR009003", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018114", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018114", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR033116", "url": "https://www.ebi.ac.uk/interpro/entry/IPR033116", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR043504", "url": "https://www.ebi.ac.uk/interpro/entry/IPR043504", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:795978", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795978", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7EY35", "url": "https://www.orthodb.org/?gene=E7EY35", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24250", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24250", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24250:SF66", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24250:SF66", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00089", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00089", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001373176", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373176", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EY35", "url": "https://www.uniprot.org/uniprotkb/E7EY35", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EY35-1", "url": "https://www.uniprot.org/uniprotkb/E7EY35-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131127-38", "url": "https://zfin.org/ZDB-GENE-131127-38", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MIWIISFLAFVASTLGCGVRQPLGWAAKESTTKKPIDGDIHEGIMQGVDALRWPWQVSIKTSSGEHLCGGSLINKFWVLTAAHCQIQARSHYVVLGQHDRSSNDGTVQVKEIAKVITHPDNNIQTLFNNDVTLLKLSSPAQMTSLVSPVCLASSSSKIVPGTLCVTTGWGRTKTELSARILQEATIPIVSQSQCKQIFGASKITNSMICAGGSGSSSCQGDSGGPLMCESSGVWYQVGIVSWGNRDCRVDFPLVYARVSYFRKWIDEIIRSN", "length": 272, "header": "tr|E7EY35-1|E7EY35_DANRE Isoform 1 of Chymotrypsin-like protease CTRL-1 precursor OS=Danio rerio OX=7955 GN=si:dkey-238d18.3 PE=4 SV=1 CANONICAL=E7EY35-1" }, "isoforms": [ { "isoform_ac": "E7EY35-1", "url": "https://www.uniprot.org/uniprotkb/E7EY35/entry#E7EY35-1", "sequence": { "sequence": "MIWIISFLAFVASTLGCGVRQPLGWAAKESTTKKPIDGDIHEGIMQGVDALRWPWQVSIKTSSGEHLCGGSLINKFWVLTAAHCQIQARSHYVVLGQHDRSSNDGTVQVKEIAKVITHPDNNIQTLFNNDVTLLKLSSPAQMTSLVSPVCLASSSSKIVPGTLCVTTGWGRTKTELSARILQEATIPIVSQSQCKQIFGASKITNSMICAGGSGSSSCQGDSGGPLMCESSGVWYQVGIVSWGNRDCRVDFPLVYARVSYFRKWIDEIIRSN", "length": 272, "header": "tr|E7EY35-1|E7EY35_DANRE Isoform 1 of Chymotrypsin-like protease CTRL-1 precursor OS=Danio rerio OX=7955 GN=si:dkey-238d18.3 PE=4 SV=1 CANONICAL=E7EY35-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.", "journal": "Brief. Bioinform.", "date": "2011", "authors": "Gaudet P, Livstone MS, Lewis SE, Thomas PD", "evidence": [ { "database": "UniProtKB", "id": "E7EY35", "url": "https://www.uniprot.org/uniprotkb/E7EY35" } ], "reference": [ { "type": "PubMed", "id": "21873635", "url": "https://glygen.org/publication/PubMed/21873635" } ] } ], "pathway": [ { "id": "dre:795978", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:795978", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "serine-type endopeptidase activity", "id": "GO:0004252", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004252", "evidence": [ { "database": "UniProtKB", "id": "E7EY35", "url": "https://www.uniprot.org/uniprotkb/E7EY35" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular region", "id": "GO:0005576", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E7EY35", "url": "https://www.uniprot.org/uniprotkb/E7EY35" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "proteolysis", "id": "GO:0006508", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006508", "evidence": [ { "database": "UniProtKB", "id": "E7EY35", "url": "https://www.uniprot.org/uniprotkb/E7EY35" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EY35", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EY35" }, { "id": "PS50240", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50240" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Peptidase S1", "eco_id": "ECO_0000259", "start_pos": 44, "end_pos": 270, "start_aa": "Ile", "end_aa": "Arg", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7EY36-1", "uniprot_ac": "E7EY36", "uniprot_id": "E7EY36_DANRE", "mass": { "chemical_mass": 63598.0, "monoisotopic_mass": 63598.0 }, "refseq": { "ac": "NP_001429400", "name": "si:ch73-269m14.2 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429400" }, "gene_names": [ { "name": "si:ch73-269m14.2", "type": "recommended", "evidence": [ { "id": "E7EY36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EY36" } ] }, { "name": "si:ch73-269m14.2", "type": "synonym", "evidence": [ { "id": "NP_001429400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429400" } ] } ], "protein_names": [ { "name": "Keratinocyte-associated transmembrane protein 2", "type": "synonym", "evidence": [ { "id": "E7EY36", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EY36/entry#names_and_taxonomy" } ] }, { "name": "si:ch73-269m14.2 precursor", "type": "synonym", "evidence": [ { "id": "NP_001429400", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429400" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: SRR32588724.2761585.1, SRR32588729.23853376.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505390, SAMEA4476745 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000021.1. On Aug 8, 2025 this sequence version replaced XP_003200957.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001429400", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429400" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EY36", "url": "https://www.uniprot.org/uniprotkb/E7EY36" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch73-269m14.2", "url": "https://www.uniprot.org/uniprotkb/E7EY36", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-120215-136", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-136", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000090747", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000090747", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100535378", "url": "https://www.ncbi.nlm.nih.gov/gene/100535378", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR037645", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037645", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100535378", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100535378", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QNDRTEC", "url": "https://omabrowser.org/oma/group/QNDRTEC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EY36", "url": "https://www.orthodb.org/?gene=E7EY36", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16502", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16502", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16502:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16502:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF17818", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17818", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001429400", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429400", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EY36", "url": "https://www.uniprot.org/uniprotkb/E7EY36", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EY36-1", "url": "https://www.uniprot.org/uniprotkb/E7EY36-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-120215-136", "url": "https://zfin.org/ZDB-GENE-120215-136", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAAVRQTPLEDSTMVKVLVLVSMLVFSVSCASLPIADGEPPATVDSKEVKAPDTQNSSDLSSPIDSTLSQSAEVLGDDSAPAVEGKNSNKSVDVPTAPIANKDTEPQDNDPKKQKNNTENLKSDTGKQKNDLKLETDPKQPKTDLNQLETEPKQLETELKQPETEPKQLETESKQPKTEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSDTEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQQLETEPKQQLETESKQPVTENKQLETENKQQNNDPVQKGDDSVQPKNDHKQQDNDPEHLKPSPAAPQPQNFTEYIAESTFLGPDLGFGDDTGNDEDDDGDDDDDEVVDENDVSNDVEVKGGSSWDDISSPEDSQGKKNYPQGYKTPPESSEINIYSTQDEDSHFFFHLVIIAFLVAIIYITYHNKRKLMLLAQSRRWRDGFCSRGVEYHRLDQNVHEAMPSLKMTNDYIF", "length": 566, "header": "tr|E7EY36-1|E7EY36_DANRE Isoform 1 of Keratinocyte-associated transmembrane protein 2 OS=Danio rerio OX=7955 GN=si:ch73-269m14.2 PE=4 SV=1 CANONICAL=E7EY36-1" }, "isoforms": [ { "isoform_ac": "E7EY36-1", "url": "https://www.uniprot.org/uniprotkb/E7EY36/entry#E7EY36-1", "sequence": { "sequence": "MAAVRQTPLEDSTMVKVLVLVSMLVFSVSCASLPIADGEPPATVDSKEVKAPDTQNSSDLSSPIDSTLSQSAEVLGDDSAPAVEGKNSNKSVDVPTAPIANKDTEPQDNDPKKQKNNTENLKSDTGKQKNDLKLETDPKQPKTDLNQLETEPKQLETELKQPETEPKQLETESKQPKTEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSDTEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQSETEPKQQLETEPKQQLETESKQPVTENKQLETENKQQNNDPVQKGDDSVQPKNDHKQQDNDPEHLKPSPAAPQPQNFTEYIAESTFLGPDLGFGDDTGNDEDDDGDDDDDEVVDENDVSNDVEVKGGSSWDDISSPEDSQGKKNYPQGYKTPPESSEINIYSTQDEDSHFFFHLVIIAFLVAIIYITYHNKRKLMLLAQSRRWRDGFCSRGVEYHRLDQNVHEAMPSLKMTNDYIF", "length": 566, "header": "tr|E7EY36-1|E7EY36_DANRE Isoform 1 of Keratinocyte-associated transmembrane protein 2 OS=Danio rerio OX=7955 GN=si:ch73-269m14.2 PE=4 SV=1 CANONICAL=E7EY36-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100535378", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100535378", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZQ77-1", "protein_name": "Similar to human chromosome 5 open reading frame 15", "gene_name": "C10h5orf15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAAASLGRMSGAAREKLSPGSGARSFGALARSLVLALLLAPVLCYGNGRGETARDQARPDGDQVPPTHGIPENTPNNATTTPPAVPENYTKPSVSQISTTLTPASTEKSGSSSSAPSPSAARSVPQEEADINEDPSMEEEDLLALNSSPATVKDTLDNGDYGEPDYDWTTNPRDEEPDDNVNIEISRESRRFRGFEDSVQVVKLSPPNREDSHFFFHLLIFAFCAAVVYVTYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVNEAMPSLKITNDYIF", "length": 280 }, "evidence": [ { "id": "MGI:2654705", "url": "https://alliancegenome.org/gene/MGI:2654705#orthology", "database": "AGR" }, { "id": "HGNC:20656", "url": "https://alliancegenome.org/gene/HGNC:20656#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8K201-1", "protein_name": "Keratinocyte-associated transmembrane protein 2", "gene_name": "Kct2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASALGRMCGAAREKLSPGPGARGLGALARSLVLALLLVPVLCSDRSENPPNNATVSSPVVVTAPGNHTSPSVSQISTTLSPASAEKSGSSSAAPTPTAAPSAPEEEADSNEDPSMEEEDLLALNSSPATGKDTLDNGDYGEPDYDWTTNPRDEEPEDINIAISKESRRFRGFQDSVEVVKLPPPNREDSHFFFHLLIFAFCAAVVYVTYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVNEAMPSLKITNDYIF", "length": 259 }, "evidence": [ { "id": "MGI:2654705", "url": "https://alliancegenome.org/gene/MGI:2654705#orthology", "database": "AGR" }, { "id": "HGNC:20656", "url": "https://alliancegenome.org/gene/HGNC:20656#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-136", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-136#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q8NC54-1", "protein_name": "Keratinocyte-associated transmembrane protein 2", "gene_name": "KCT2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAVPKRMRGPAQAKLLPGSAIQALVGLARPLVLALLLVSAALSSVVSRTDSPSPTVLNSHISTPNVNALTHENQTKPSISQISTTLPPTTSTKKSGGASVVPHPSPTPLSQEEADNNEDPSIEEEDLLMLNSSPSTAKDTLDNGDYGEPDYDWTTGPRDDDESDDTLEENRGYMEIEQSVKSFKMPSSNIEEEDSHFFFHLIIFAFCIAVVYITYHNKRKIFLLVQSRKWRDGLCSKTVEYHRLDQNVNEAMPSLKITNDYIF", "length": 265 }, "evidence": [ { "id": "MGI:2654705", "url": "https://alliancegenome.org/gene/MGI:2654705#orthology", "database": "AGR" }, { "id": "HGNC:20656", "url": "https://alliancegenome.org/gene/HGNC:20656#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-120215-136", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-120215-136#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 116, "end_pos": 118, "annotation": "n_glycosylation_sequon" }, { "start_pos": 406, "end_pos": 408, "annotation": "n_glycosylation_sequon" }, { "start_pos": 56, "end_pos": 58, "annotation": "n_glycosylation_sequon" }, { "start_pos": 89, "end_pos": 91, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 116, "end_pos": 118 }, { "start_pos": 406, "end_pos": 408 }, { "start_pos": 56, "end_pos": 58 }, { "start_pos": 89, "end_pos": 91 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EY77-1", "uniprot_ac": "E7EY77", "uniprot_id": "E7EY77_DANRE", "mass": { "chemical_mass": 30038.0, "monoisotopic_mass": 30038.0 }, "refseq": { "ac": "XP_002665267", "name": "uncharacterized protein si:dkey-16j16.4", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665267" }, "gene_names": [ { "name": "si:dkey-16j16.4", "type": "recommended", "evidence": [ { "id": "E7EY77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EY77" } ] }, { "name": "si:dkey-16j16.4", "type": "synonym", "evidence": [ { "id": "XP_002665267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665267" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkey-16j16.4", "type": "synonym", "evidence": [ { "id": "E7EY77", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EY77/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkey-16j16.4", "type": "synonym", "evidence": [ { "id": "XP_002665267", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665267" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_002665267", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_002665267" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EY77", "url": "https://www.uniprot.org/uniprotkb/E7EY77" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-16j16.4", "url": "https://www.uniprot.org/uniprotkb/E7EY77", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-041111-271", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-041111-271", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000089862", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000089862", "database": "Bgee", "categories": [ "Gene 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This record is derived from a genomic sequence (NC_133179) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009299145", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009299145" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EY84", "url": "https://www.uniprot.org/uniprotkb/E7EY84" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-223a21.4", "url": "https://www.uniprot.org/uniprotkb/E7EY84", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110913-57", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110913-57", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000100842", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000100842", "database": "Bgee", "categories": [ "Gene 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"synonym", "evidence": [ { "id": "NP_001314975", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314975" } ] }, { "name": "si:ch211-263b6.1", "type": "synonym", "evidence": [ { "id": "NP_001314975", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314975" }, { "id": "E7EYE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYE2" } ] } ], "protein_names": [ { "name": "Opioid growth factor receptor-like protein 1", "type": "synonym", "evidence": [ { "id": "E7EYE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYE2/entry#names_and_taxonomy" } ] }, { "name": "opioid growth factor receptor-like protein 1", "type": "synonym", "evidence": [ { "id": "NP_001314975", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314975" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01003877.1, GFIL01029087.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000013.1. On Jun 3, 2016 this sequence version replaced XP_688429.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001314975", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314975" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EYE2", "url": "https://www.uniprot.org/uniprotkb/E7EYE2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ogfrl1", "url": "https://www.uniprot.org/uniprotkb/E7EYE2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-061207-32", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-32", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000061223", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000061223", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "559942", "url": "https://www.ncbi.nlm.nih.gov/gene/559942", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006757", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006757", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039574", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039574", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:559942", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559942", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MHKKPKD", "url": "https://omabrowser.org/oma/group/MHKKPKD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EYE2", "url": "https://www.orthodb.org/?gene=E7EYE2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14015", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14015", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14015:SF0", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14015:SF0", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04664", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04664", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001314975", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314975", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EYE2", "url": "https://www.uniprot.org/uniprotkb/E7EYE2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EYE2-1", "url": "https://www.uniprot.org/uniprotkb/E7EYE2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-061207-32", "url": "https://zfin.org/ZDB-GENE-061207-32", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGNLMGSWRYKEPSTVEECDSTWETDSESDEHQPGGEEEDSGISESMSPAEAARGGEQLEHGSPQFGDMMESSTRMKRSFYAAKDLYKYRHSYPNYKEPRQPNEYRNLRFYLNKIPLVPDGIYIEEILTKWRGDYDKLEHNHTYIQWLFPLREQGLNFYAQELTQDEIKEFQSTREAKRRFLLAYTIMLDFFGIKLLDKNGNVSRASNWQDRFQHLNESQHNYLRITRILKSLGELGFESFKLPLVRLLLEEALVEGTLPNMRHSALEYFVFTLRQHAQRRALLRFARRHYQPPENFIWGPPKKKRIPASISTGTRMVKNEVVERSVAKARSPREGRNNAEREMEDMEERKSGEWKLAKGAKMLQEGRGRVVIEEYIETIPL", "length": 382, "header": "tr|E7EYE2-1|E7EYE2_DANRE Isoform 1 of Opioid growth factor receptor-like protein 1 OS=Danio rerio OX=7955 GN=ogfrl1 PE=3 SV=1 CANONICAL=E7EYE2-1" }, "isoforms": [ { "isoform_ac": "E7EYE2-1", "url": "https://www.uniprot.org/uniprotkb/E7EYE2/entry#E7EYE2-1", "sequence": { "sequence": "MGNLMGSWRYKEPSTVEECDSTWETDSESDEHQPGGEEEDSGISESMSPAEAARGGEQLEHGSPQFGDMMESSTRMKRSFYAAKDLYKYRHSYPNYKEPRQPNEYRNLRFYLNKIPLVPDGIYIEEILTKWRGDYDKLEHNHTYIQWLFPLREQGLNFYAQELTQDEIKEFQSTREAKRRFLLAYTIMLDFFGIKLLDKNGNVSRASNWQDRFQHLNESQHNYLRITRILKSLGELGFESFKLPLVRLLLEEALVEGTLPNMRHSALEYFVFTLRQHAQRRALLRFARRHYQPPENFIWGPPKKKRIPASISTGTRMVKNEVVERSVAKARSPREGRNNAEREMEDMEERKSGEWKLAKGAKMLQEGRGRVVIEEYIETIPL", "length": 382, "header": "tr|E7EYE2-1|E7EYE2_DANRE Isoform 1 of Opioid growth factor receptor-like protein 1 OS=Danio rerio OX=7955 GN=ogfrl1 PE=3 SV=1 CANONICAL=E7EYE2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7EYE2", "url": "https://www.uniprot.org/uniprotkb/E7EYE2" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "IFN-Stimulated Genes in Zebrafish and Humans Define an Ancient Arsenal of Antiviral Immunity.", "journal": "J. Immunol.", "date": "2019", "authors": "Levraud Jean-Pierre, Jouneau Luc, Briolat Val\u00e9rie, Laghi Valerio, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "E7EYE2", "url": "https://www.uniprot.org/uniprotkb/E7EYE2" } ], "reference": [ { "type": "PubMed", "id": "31732531", "url": "https://glygen.org/publication/PubMed/31732531" } ] }, { "title": "A CRISPR-Cas9-mediated F0 screen to identify pro-regenerative genes in the zebrafish retinal pigment epithelium.", "journal": "Sci. Rep.", "date": "2023", "authors": "Lu Fangfang, Leach Lyndsay L, Gross Jeffrey M", "evidence": [ { "database": "UniProtKB", "id": "E7EYE2", "url": "https://www.uniprot.org/uniprotkb/E7EYE2" } ], "reference": [ { "type": "PubMed", "id": "36823429", "url": "https://glygen.org/publication/PubMed/36823429" } ] } ], "pathway": [ { "id": "dre:559942", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:559942", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V0XD65-1", "protein_name": "Opioid growth factor receptor like 1", "gene_name": "OGFRL1", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MVEEPECWGRRGREAWHPPAVSWGPSAAVARLALTQRTAALLGHQCRRSLPRMQSGPTGVGFLAYKLPLCKIKQVLAFIVSFLLDARYWWLADACVSGCCLLSDGTELTAKPKRSFYAARDLYKYRHQYPQNFKDLRYQNDLCNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLIDKTGNVARAANWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVEDTIPNIKQSALEYFVYTIRDRRERRKLLRFAQQHYSPSEHFIWGPPRKQKSEGSKTNKKPASPISIHSSYISKHKKLKEPKSTSTSGTSASKATEERKVEITKNGEENDQDEQEMNCDAVKQSSEKNSSTDTGQLSKSEEIHDPSDKKEDASQSKKDDENMDNDCGNHPGVIDISLCDTENCSNNVSSDLQDSLDKDSPSGGTTTKTKDEIKL", "length": 506 }, "evidence": [ { "id": "E7EYE2", "url": "https://omabrowser.org/oma/group/E7EYE2/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "F1N3J9-1", "protein_name": "Opioid growth factor receptor like 1", "gene_name": "OGFRL1", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MGNLLGGVSVREPTTVEDCDSTWQTDSEPELEEPGPGGGEGPGREPAQPPEPAEPAEPPERAGGRLRAGPAPEPDPEAAGAEQGTDSTEAPAKPKRSFYAARDLYKYRHQYPQNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLIDKTGNVARAVNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPRKAQPEGSKAQKPPGPPTAGQHGQMSMHKKPKDSKNASSAAHGISKAAEDKKVASKESEEMDKPSEEPGSEAAQPGDPGQDEVANNSSPRAAKTVTHPEEQKESASPSEKDEASDTRNQDGGSPGDAGSHDDAALP", "length": 457 }, "evidence": [ { "id": "E7EYE2", "url": "https://omabrowser.org/oma/group/E7EYE2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q4KLH3-1", "protein_name": "Opioid growth factor receptor-like protein 1", "gene_name": "Ogfrl1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEQPGPAGGGEGQEQDEREQPEQPPERAGGRPRASPVPEDHAEAAGAEQGGDSTEGNAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLIDKTGNVARAVNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPKKEQPERSKAQKTPTLPALGSNGQTSTHKKSKDSKNSSAASHLNNKTVEEKKVASREPGEETDKPSPEASSEDTKPRNSEDDNAADQSESPPKKTVNDSAGKGECPTTSSEKDGEGENQSKDSENPENTSCHAEVVSQQNVTNPQTSSG", "length": 465 }, "evidence": [ { "id": "MGI:1917405", "url": "https://alliancegenome.org/gene/MGI:1917405#orthology", "database": "AGR" }, { "id": "HGNC:21378", "url": "https://alliancegenome.org/gene/HGNC:21378#orthology", "database": "AGR" }, { "id": "E7EYE2", "url": "https://omabrowser.org/oma/group/E7EYE2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q5TC84-1", "protein_name": "Opioid growth factor receptor-like protein 1", "gene_name": "OGFRL1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEEPGPGGGSEGPGQESEQPAQPPEQAGGRPGASPAPDEDAEAAGAEQGGDSTEATAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLSKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLTDKTGNVARAVNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPRKEQSEGSKAQKMSSPLASSHNSQTSMHKKAKDSKNSSSAVHLNSKTAEDKKVAPKEPVEETDRPSPEPSNEAAKPRNTEKDSNAENMNSQPEKTVTTPTEKKESVSPENNEEGGNDNQDNENPGNTNCHDVVLVQ", "length": 451 }, "evidence": [ { "id": "MGI:1917405", "url": "https://alliancegenome.org/gene/MGI:1917405#orthology", "database": "AGR" }, { "id": "HGNC:21378", "url": "https://alliancegenome.org/gene/HGNC:21378#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-32", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-32#orthology", "database": "AGR" }, { "id": "E7EYE2", "url": "https://omabrowser.org/oma/group/E7EYE2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VE52-1", "protein_name": "Opioid growth factor receptor-like protein 1", "gene_name": "Ogfrl1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGNLLGGVSFREPTTVEDCDSTWQTDSEPEPEQPGPAGGGEGQQHDEPEQPKQPPERAGGRPRASPVPEDHAEAAGAEQGGESTEGNAKPKRSFYAARDLYKYRHQYPNFKDIRYQNDLSNLRFYKNKIPFKPDGVYIEEVLNKWKGDYEKLEHNHTYIQWLFPLREQGLNFYAKELTTYEIEEFKKTKEAIRRFLLAYKMMLEFFGIKLIDKTGNVARAGNWQERFQHLNESQHNYLRITRILKSLGELGYESFKSPLVKFILHEALVENTIPNIKQSALEYFVYTIRDRRERRKLLRFAQKHYTPSENFIWGPPKKELPERSKAQKTPTLPASGSNGQTSTHKKSKDSKISPGASHVNSKSVEEKKGASREPGEEADKPSPEPGSGDPKPRNTEKDSAADQSDSPPEKTVPDTAGKGECPTSSEKDGEGEDQSKDSENPENAGCHAEVVAQQNATNPQTSSG", "length": 464 }, "evidence": [ { "id": "MGI:1917405", "url": "https://alliancegenome.org/gene/MGI:1917405#orthology", "database": "AGR" }, { "id": "HGNC:21378", "url": "https://alliancegenome.org/gene/HGNC:21378#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-061207-32", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-061207-32#orthology", "database": "AGR" }, { "id": "E7EYE2", "url": "https://omabrowser.org/oma/group/E7EYE2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7EYE2", "url": "https://www.uniprot.org/uniprotkb/E7EYE2" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "opioid growth factor receptor activity", "id": "GO:0140625", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0140625", "evidence": [ { "database": "UniProtKB", "id": "E7EYE2", "url": "https://www.uniprot.org/uniprotkb/E7EYE2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 141, "end_pos": 143, "annotation": "n_glycosylation_sequon" }, { "start_pos": 202, "end_pos": 204, "annotation": "n_glycosylation_sequon" }, { "start_pos": 217, "end_pos": 219, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EYE2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYE2" }, { "id": "PF04664", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04664" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Opioid growth factor receptor (OGFr) conserved", "eco_id": "ECO_0000259", "start_pos": 101, "end_pos": 305, "start_aa": "Gln", "end_aa": "Lys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 141, "end_pos": 143 }, { "start_pos": 202, "end_pos": 204 }, { "start_pos": 217, "end_pos": 219 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 3 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7EYG3-1", "uniprot_ac": "E7EYG3", "uniprot_id": "E7EYG3_DANRE", "mass": { "chemical_mass": 63055.0, "monoisotopic_mass": 63055.0 }, "refseq": { "ac": "XP_017207041", "name": "uncharacterized protein zmp:0000000951", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207041" }, "gene_names": [ { "name": "zmp:0000000951", "type": "recommended", "evidence": [ { "id": "E7EYG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYG3" } ] }, { "name": "zmp:0000000951", "type": "synonym", "evidence": [ { "id": "XP_017207041", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207041" } ] } ], "protein_names": [ { "name": "Uncharacterized protein zmp:0000000951", "type": "synonym", "evidence": [ { "id": "E7EYG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYG3/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein zmp:0000000951", "type": "synonym", "evidence": [ { "id": "XP_017207041", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207041" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017207041", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207041" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EYG3", "url": "https://www.uniprot.org/uniprotkb/E7EYG3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zmp:0000000951", "url": "https://www.uniprot.org/uniprotkb/E7EYG3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-954", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-954", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "101885248", "url": "https://www.ncbi.nlm.nih.gov/gene/101885248", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR007743", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007743", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR030385", "url": "https://www.ebi.ac.uk/interpro/entry/IPR030385", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885248", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885248", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CDVYILV", "url": "https://omabrowser.org/oma/group/CDVYILV/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EYG3", "url": "https://www.orthodb.org/?gene=E7EYG3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14143", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14143", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14143:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14143:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF05049", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF05049", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017207041", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017207041", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EYG3", "url": "https://www.uniprot.org/uniprotkb/E7EYG3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EYG3-1", "url": "https://www.uniprot.org/uniprotkb/E7EYG3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-954", "url": "https://zfin.org/ZDB-GENE-130530-954", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MEGKLSDEKVKCLLAPWRFSLRGPGFESRLVAALQLFEHFPLDIAVTGGTQAANAQLASIISGSDEEIEEEVWETEDEDDDEEEETDEDEEEWEEEESADEEPSIKLNANHQSSKIKRVRISENTQYIGSGISDFVHCQFPNVRLWTVQGHPTSNSIIKQSNQQYESTHYDVLLILTSEQHKDDHMWIKMELHDRDQPFFLVQAEQDWDVLEEKPSGPCMTCAWERMRARKLELQKRSEKAFGETSSSTDSPANTPQDSELVKMKDITKVLAEALPELRIKAFSQFLVAITKELKIPKLLTDDSQFVVSTALRSMKINQDDLDQISKLSQTRDFTDNPSKLQAILGALDHFRLDVGVLGETGCGSSSLINALLGLKNSNETAALTGVTETTKEAVEYALPDSHNIRFWDLPGLGKIGDLSSLSANAFSSSEGQQVASVLALCDVYILVSPLRVRLRTIQLLQQASSMGKECYLVISMVDLIEDKAVEEVRQWTEKVLSKLDIQQSLFLVSANYPETLDLAKLKGMLKAAIPSHKKVALARYVSKQLDEDVFWKRSDSCKFM", "length": 561, "header": "tr|E7EYG3-1|E7EYG3_DANRE Isoform 1 of Uncharacterized protein zmp:0000000951 OS=Danio rerio OX=7955 GN=zmp:0000000951 PE=3 SV=1 CANONICAL=E7EYG3-1" }, "isoforms": [ { "isoform_ac": "E7EYG3-1", "url": "https://www.uniprot.org/uniprotkb/E7EYG3/entry#E7EYG3-1", "sequence": { "sequence": "MEGKLSDEKVKCLLAPWRFSLRGPGFESRLVAALQLFEHFPLDIAVTGGTQAANAQLASIISGSDEEIEEEVWETEDEDDDEEEETDEDEEEWEEEESADEEPSIKLNANHQSSKIKRVRISENTQYIGSGISDFVHCQFPNVRLWTVQGHPTSNSIIKQSNQQYESTHYDVLLILTSEQHKDDHMWIKMELHDRDQPFFLVQAEQDWDVLEEKPSGPCMTCAWERMRARKLELQKRSEKAFGETSSSTDSPANTPQDSELVKMKDITKVLAEALPELRIKAFSQFLVAITKELKIPKLLTDDSQFVVSTALRSMKINQDDLDQISKLSQTRDFTDNPSKLQAILGALDHFRLDVGVLGETGCGSSSLINALLGLKNSNETAALTGVTETTKEAVEYALPDSHNIRFWDLPGLGKIGDLSSLSANAFSSSEGQQVASVLALCDVYILVSPLRVRLRTIQLLQQASSMGKECYLVISMVDLIEDKAVEEVRQWTEKVLSKLDIQQSLFLVSANYPETLDLAKLKGMLKAAIPSHKKVALARYVSKQLDEDVFWKRSDSCKFM", "length": 561, "header": "tr|E7EYG3-1|E7EYG3_DANRE Isoform 1 of Uncharacterized protein zmp:0000000951 OS=Danio rerio OX=7955 GN=zmp:0000000951 PE=3 SV=1 CANONICAL=E7EYG3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885248", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885248", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "GTP binding", "id": "GO:0005525", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005525", "evidence": [ { "database": "UniProtKB", "id": "E7EYG3", "url": "https://www.uniprot.org/uniprotkb/E7EYG3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7EYG3", "url": "https://www.uniprot.org/uniprotkb/E7EYG3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 379, "end_pos": 381, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EYG3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYG3" }, { "id": "PS51716", "database": "PROSITE", "url": "https://prosite.expasy.org/PS51716" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "IRG-type G", "eco_id": "ECO_0000259", "start_pos": 351, "end_pos": 529, "start_aa": "Phe", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 379, "end_pos": 381 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EYL9-1", "uniprot_ac": "E7EYL9", "uniprot_id": "E7EYL9_DANRE", "mass": { "chemical_mass": 69924.0, "monoisotopic_mass": 69924.0 }, "refseq": { "ac": "XP_690018", "name": "uncharacterized protein fam83e isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690018" }, "gene_names": [ { "name": "fam83e", "type": "recommended", "evidence": [ { "id": "E7EYL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYL9" } ] }, { "name": "fam83e", "type": "synonym", "evidence": [ { "id": "XP_690018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690018" } ] } ], "protein_names": [ { "name": "Uncharacterized protein fam83e isoform X1", "type": "synonym", "evidence": [ { "id": "E7EYL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYL9/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein fam83e isoform X1", "type": "synonym", "evidence": [ { "id": "XP_690018", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690018" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_690018.5. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_690018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690018" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EYL9", "url": "https://www.uniprot.org/uniprotkb/E7EYL9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam83e", "url": "https://www.uniprot.org/uniprotkb/E7EYL9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141215-21", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141215-21", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000089489", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000089489", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "561520", "url": "https://www.ncbi.nlm.nih.gov/gene/561520", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012461", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012461", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050944", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050944", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "DWHTEAP", "url": "https://omabrowser.org/oma/group/DWHTEAP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EYL9", "url": "https://www.orthodb.org/?gene=E7EYL9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR16181:SF29", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR16181:SF29", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07894", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_690018", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690018", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58GTY0", "url": "https://www.uniprot.org/uniprotkb/A0AC58GTY0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GTY0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GTY0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EYL9", "url": "https://www.uniprot.org/uniprotkb/E7EYL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EYL9-1", "url": "https://www.uniprot.org/uniprotkb/E7EYL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-141215-21", "url": "https://zfin.org/ZDB-GENE-141215-21", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSNTQEQSLNENIVFAPLSESSPEFLHCEEERYCVESLISSGPQAFYTQLHQEQIGSFLSSGEVKQISSWAEDFHQSDGLQEEGNGEVEVGSEGEDFSGHYFPTESDTPAPCLELGWPERAMWMDTGRVNVYTNPPTEQSPSIREVLRRLIQAATRLIAVVTDKLSDNAVINDLQNAASRGVPVYIILNKRSVEEKCSIHRLQHPNIMIRILGGKTFLTRDSRMVIGELKDNFVLVDLETVMLGSYSFTWSDTYLHRQLVTVMSGPVVESFDREFRTLYAASLPIPDAWKTGKQTSEPKIYKKLLPLNINKVEISEFVSSPPPPPTDCVLDWEAMGVIRRFPDGSLSPPEAAPELQFPHRHLLDRLPVGGGWEIPHNDYNSRFLTGYPEEGKLNSMFLADLRHPEYQRPRYHYSPGEMQCNEPMNRSLQMADRVAYPLLNTENEERFPVYRSRTHRTDLSSEEELGSALRREPFLRRDRGLGETLNTETNAHVNLKKPSDLSRSKTFSTLSDIFKRVNARATSGQMKTEDKATGVSKSTMDLNLQRTDMPSNPRNINSDNIALTPALALMKKRNDEVKTGLLRSMPSVFTPSFRTAGFGLQRETWRSPFRRNDEEQ", "length": 616, "header": "tr|E7EYL9-1|E7EYL9_DANRE Isoform 1 of Uncharacterized protein fam83e isoform X1 OS=Danio rerio OX=7955 GN=fam83e PE=3 SV=1 CANONICAL=E7EYL9-1" }, "isoforms": [ { "isoform_ac": "A0AC58GTY0-1", "url": "https://www.uniprot.org/uniprotkb/E7EYL9/entry#A0AC58GTY0-1", "sequence": { "sequence": "MTFSRTRRQCCYMKMRDFSAVYGCSNEQTKKAKHKGRTFHSFTWSDTYLHRQLVTVMSGPVVESFDREFRTLYAASLPIPDAWKTGKQTSEPKIYKKLLPLNINKVEISEFVSSPPPPPTDCVLDWEAMGVIRRFPDGSLSPPEAAPELQFPHRHLLDRLPVGGGWEIPHNDYNSRFLTGYPEEGKLNSMFLADLRHPEYQRPRYHYSPGEMQCNEPMNRSLQMADRVAYPLLNTENEERFPVYRSRTHRTDLSSEEELGSALRREPFLRRDRGLGETLNTETNAHVNLKKPSDLSRSKTFSTLSDIFKRVNARATSGQMKTEDKATGVSKSTMDLNLQRTDMPSNPRNINSDNIALTPALALMKKRNDEVKTGLLRSMPSVFTPSFRTAGFGLQRETWRSPFRRNDEEQ", "length": 410, "header": "tr|A0AC58GTY0-1|A0AC58GTY0_DANRE Computationally mapped isoform of Uncharacterized protein fam83e isoform X2 OS=Danio rerio OX=7955 GN=fam83e PE=3 SV=1 CANONICAL=E7EYL9-1" }, "locus": {} }, { "isoform_ac": "E7EYL9-1", "url": "https://www.uniprot.org/uniprotkb/E7EYL9/entry#E7EYL9-1", "sequence": { "sequence": "MSNTQEQSLNENIVFAPLSESSPEFLHCEEERYCVESLISSGPQAFYTQLHQEQIGSFLSSGEVKQISSWAEDFHQSDGLQEEGNGEVEVGSEGEDFSGHYFPTESDTPAPCLELGWPERAMWMDTGRVNVYTNPPTEQSPSIREVLRRLIQAATRLIAVVTDKLSDNAVINDLQNAASRGVPVYIILNKRSVEEKCSIHRLQHPNIMIRILGGKTFLTRDSRMVIGELKDNFVLVDLETVMLGSYSFTWSDTYLHRQLVTVMSGPVVESFDREFRTLYAASLPIPDAWKTGKQTSEPKIYKKLLPLNINKVEISEFVSSPPPPPTDCVLDWEAMGVIRRFPDGSLSPPEAAPELQFPHRHLLDRLPVGGGWEIPHNDYNSRFLTGYPEEGKLNSMFLADLRHPEYQRPRYHYSPGEMQCNEPMNRSLQMADRVAYPLLNTENEERFPVYRSRTHRTDLSSEEELGSALRREPFLRRDRGLGETLNTETNAHVNLKKPSDLSRSKTFSTLSDIFKRVNARATSGQMKTEDKATGVSKSTMDLNLQRTDMPSNPRNINSDNIALTPALALMKKRNDEVKTGLLRSMPSVFTPSFRTAGFGLQRETWRSPFRRNDEEQ", "length": 616, "header": "tr|E7EYL9-1|E7EYL9_DANRE Isoform 1 of Uncharacterized protein fam83e isoform X1 OS=Danio rerio OX=7955 GN=fam83e PE=3 SV=1 CANONICAL=E7EYL9-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 326, "start_aa": "Thr", "end_pos": 326, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr326", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZT45-1", "protein_name": "Family with sequence similarity 83, member E", "gene_name": "Fam83e", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAASQLAALEGEELGAVEPAPTKACPASLYSEGQRLALEALLSSGEEAFWACVQQERLPPFLSADEAQALATAAEDWIVPSQEPGATGTGAGIADGDFGSLTYWPRQSEEPAPSLRLGWPEDIAWKGITRAQLYTQPPGEGQPPVKELVRQEIQAARKLVAVVMDIFTDPDLLRDMVDAATRRWIPVYLLLDHQHLPAFLALAQQLGVNLWTTENLDIRTVQGHTFQSRRRRQVSGHVREKFLLLDGDRVISGSYSFTWSDSRLHRGLVTLLTGEIADAFSQEFRVLYAASRPLPPAPARSPLFSPPEGPQLPRSPHRVALRCPVAPVAPLLSDGPLAHRLAACHILEGDRRETPTTTGPALSDILRSVQRTRTTSGPPTRPSRSLWDLSRLSQLSGSSDGENEPKKSWGSKDTPARALMRQRGTGGGPRAEMDLRSQPWVGPLPIPAQRRLRYLSPAQRRLGDNATTSDWASGSGSGRRR", "length": 481 }, "evidence": [ { "id": "MGI:1921063", "url": "https://alliancegenome.org/gene/MGI:1921063#orthology", "database": "AGR" }, { "id": "HGNC:25972", "url": "https://alliancegenome.org/gene/HGNC:25972#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q2M2I3-1", "protein_name": "Protein FAM83E", "gene_name": "FAM83E", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAASQLAALEGVDSGPRVPGASPGFLYSEGQRLALEALLSKGAEAFQTCVQREELWPFLSADEVQGLAAAAEDWTVAKQEPSGMAEGATTTDVDAGSLSYWPGQSEQPAPVLRLGWPVDSAWKGITRAQLYTQPPGEGQPPLKELVRLEIQAAHKLVAVVMDVFTDPDLLLDLVDAATRRWVPVYLLLDRQQLPAFLELAQQLGVNPWNTENVDVRVVRGCSFQSRWRRQVSGTVREKFVLLDGERVISGSYSFTWSDARLHRGLVTLLTGEIVDAFSLEFRTLYAASCPLPPAPPQKPSVIGGLQRGRSPHRVSRRRSVAPASPPPPDGPLAHRLAACRVSPATPGPALSDILRSVQRARTPSGPPARPSRSMWDLSRLSQLSGSSDGDNELKKSWGSKDTPAKALMRQRGTGGGPWGEVDSRPPWGGALPLPPAHRLRYLSPARRRFGGDATFKLQEPRGVRPSDWAPRAGLGGQP", "length": 478 }, "evidence": [ { "id": "MGI:1921063", "url": "https://alliancegenome.org/gene/MGI:1921063#orthology", "database": "AGR" }, { "id": "HGNC:25972", "url": "https://alliancegenome.org/gene/HGNC:25972#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141215-21", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141215-21#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q80XS7-1", "protein_name": "Protein FAM83E", "gene_name": "Fam83e", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAASQLAALEGEELGAGEPALTKASPAVLYSEGQRLALEALLSSGEETFWACVQQERLPPFLSADEAQALATAAEDWLVPSQEPGAAGTGTAITDGDVGSLTYWPRQSEEPAPLLRLGWPEDTAWKGITRAQLYTQPPGEGQPPIKELVHQEIQAARKLVAVVMDVFTDPDLLRDMVDAATRRWIPVYLLLDHQHLPAFLALAQQLGVNLWTTENLDIRTVQGHTFQSRRRRQVSGHVREKFVLLDGDRVISGSYSFTWSDSRLHRSLVTLLTGEIADAFNQEFRVLYAASRPLSAAPARSPLFSPPEGPQLPRSPHRVALRCPVAPVAPLLSDGPLAQRLAACHILERDKQETPTTTGPALSDILRSVQRTRTTSGPPTRPSRSLWDLSRLSQLSGSSDGENESKKFWVSKDTPARALMRQRGTGGGPRAEMDSRSQPWGGPLPSIPARRLRYLSPAQRRLGDNATTSDWASGSGSGRRR", "length": 481 }, "evidence": [ { "id": "MGI:1921063", "url": "https://alliancegenome.org/gene/MGI:1921063#orthology", "database": "AGR" }, { "id": "HGNC:25972", "url": "https://alliancegenome.org/gene/HGNC:25972#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141215-21", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141215-21#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "signal transduction", "id": "GO:0007165", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0007165", "evidence": [ { "database": "UniProtKB", "id": "E7EYL9", "url": "https://www.uniprot.org/uniprotkb/E7EYL9" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "protein kinase binding", "id": "GO:0019901", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0019901", "evidence": [ { "database": "UniProtKB", "id": "E7EYL9", "url": "https://www.uniprot.org/uniprotkb/E7EYL9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 425, "end_pos": 427, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EYL9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYL9" }, { "id": "PF07894", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07894" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Scaffolding anchor of CK1", "eco_id": "ECO_0000259", "start_pos": 17, "end_pos": 283, "start_aa": "Pro", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 326 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 425, "end_pos": 427 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EYP8-1", "uniprot_ac": "E7EYP8", "uniprot_id": "E7EYP8_DANRE", "mass": { "chemical_mass": 27598.0, "monoisotopic_mass": 27598.0 }, "refseq": { "ac": "NP_001314930", "name": "apoptosis facilitator Bcl-2-like protein 14", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314930" }, "gene_names": [ { "name": "LOC101885512", "type": "recommended", "evidence": [ { "id": "E7EYP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYP8" } ] }, { "name": "LOC101885512", "type": "synonym", "evidence": [ { "id": "NP_001314930", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314930" } ] } ], "protein_names": [ { "name": "Apoptosis facilitator Bcl-2-like protein 14", "type": "synonym", "evidence": [ { "id": "E7EYP8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYP8/entry#names_and_taxonomy" } ] }, { "name": "apoptosis facilitator Bcl-2-like protein 14", "type": "synonym", "evidence": [ { "id": "NP_001314930", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314930" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH437325.1, EH549025.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505384, SAMEA4476750 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH437325.1 and EH570146.1. On Jun 2, 2016 this sequence version replaced XP_009298317.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001314930", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314930" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EYP8", "url": "https://www.uniprot.org/uniprotkb/E7EYP8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101885512", "url": "https://www.uniprot.org/uniprotkb/E7EYP8", "locus": {} } ], "crossref": [ { "id": "ENSDARG00000090401", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000090401", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101885512", "url": "https://www.ncbi.nlm.nih.gov/gene/101885512", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR036834", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036834", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101885512", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885512", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QEANGHT", "url": "https://omabrowser.org/oma/group/QEANGHT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EYP8", "url": "https://www.orthodb.org/?gene=E7EYP8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14965", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14965", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14965:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14965:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001314930", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314930", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EYP8", "url": "https://www.uniprot.org/uniprotkb/E7EYP8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EYP8-1", "url": "https://www.uniprot.org/uniprotkb/E7EYP8-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MAQDQVNADIQTPEVDSLEFKLLLAYTHKRRPTDTRLQQNIQQKERSKPKVFRKNKKFSFLKCIKPQTDDNDVCPAPQPATLQDVKVDEMEKVASVLTEISDSLDIPSDIAADGDDENVDVVKQLADMLRTHGDDLDEKIKADIRLREILQSSFKYSFFQKVLETFCKSVSSDVPPPQQEDEKMNVALICEATSLLSSISLHPMNQVLGFGAHYLQEKYPTWVSRNMQLSNGEVADESKEEVH", "length": 243, "header": "tr|E7EYP8-1|E7EYP8_DANRE Isoform 1 of Apoptosis facilitator Bcl-2-like protein 14 OS=Danio rerio OX=7955 GN=LOC101885512 PE=4 SV=1 CANONICAL=E7EYP8-1" }, "isoforms": [ { "isoform_ac": "E7EYP8-1", "url": "https://www.uniprot.org/uniprotkb/E7EYP8/entry#E7EYP8-1", "sequence": { "sequence": "MAQDQVNADIQTPEVDSLEFKLLLAYTHKRRPTDTRLQQNIQQKERSKPKVFRKNKKFSFLKCIKPQTDDNDVCPAPQPATLQDVKVDEMEKVASVLTEISDSLDIPSDIAADGDDENVDVVKQLADMLRTHGDDLDEKIKADIRLREILQSSFKYSFFQKVLETFCKSVSSDVPPPQQEDEKMNVALICEATSLLSSISLHPMNQVLGFGAHYLQEKYPTWVSRNMQLSNGEVADESKEEVH", "length": 243, "header": "tr|E7EYP8-1|E7EYP8_DANRE Isoform 1 of Apoptosis facilitator Bcl-2-like protein 14 OS=Danio rerio OX=7955 GN=LOC101885512 PE=4 SV=1 CANONICAL=E7EYP8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101885512", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101885512", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E7EYP8", "url": "https://www.uniprot.org/uniprotkb/E7EYP8" } ], "pmid": "" }, { "name": "positive regulation of extrinsic apoptotic signaling pathway", "id": "GO:2001238", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:2001238", "evidence": [ { "database": "UniProtKB", "id": "E7EYP8", "url": "https://www.uniprot.org/uniprotkb/E7EYP8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"E7EYT5_DANRE", "mass": { "chemical_mass": 27664.0, "monoisotopic_mass": 27664.0 }, "refseq": { "ac": "NP_001314844", "name": "regulator of G-protein signaling 9-binding protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314844" }, "gene_names": [ { "name": "rgs9bp", "type": "recommended", "evidence": [ { "id": "E7EYT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYT5" } ] }, { "name": "R9AP", "type": "synonym", "evidence": [ { "id": "NP_001314844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314844" }, { "id": "E7EYT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYT5" } ] }, { "name": "rgs9bp", "type": "synonym", "evidence": [ { "id": "NP_001314844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314844" } ] } ], "protein_names": [ { "name": "Regulator of G-protein signaling 9-binding protein", "type": "synonym", "evidence": [ { "id": "E7EYT5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYT5/entry#names_and_taxonomy" } ] }, { "name": "regulator of G-protein signaling 9-binding protein", "type": "synonym", "evidence": [ { "id": "NP_001314844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314844" } ] }, { "name": "regulator of G-protein signalling 9 binding protein", "type": "synonym", "evidence": [ { "id": "NP_001314844", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314844" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: DN893693.1, EH433351.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505373 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000007.1. On May 28, 2016 this sequence version replaced XP_691153.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001314844", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314844" } ] } ], "disease": [ { "disease_id": "DOID:0070364", "recommended_name": { "id": "DOID:0070364", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070364", "name": "bradyopsia 2", "description": "A braydopsia that has_material_basis_in homozygous mutation in the RGS9BP gene on chromosome 19q13." }, "synonyms": [ { "id": "DOID:0070364", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070364", "name": "prolonged electroretinal response suppression 2", "description": "" }, { "id": "MONDO:0958190", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0958190", "name": "prolonged electroretinal response suppression 2", "description": "" }, { "id": "MIM:620344", "resource": "MIM", "url": "https://www.omim.org/entry/620344", "name": "Prolonged electroretinal response suppression 2", "description": "Prolonged electroretinal response suppression 2" } ], "unlinked_id_list": [], "evidence": [ { "id": "0070364", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0070364" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EYT5", "url": "https://www.uniprot.org/uniprotkb/E7EYT5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "rgs9bp", "url": "https://www.uniprot.org/uniprotkb/E7EYT5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030728-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030728-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000009466", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000009466", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "562687", "url": "https://www.ncbi.nlm.nih.gov/gene/562687", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026512", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026512", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:562687", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562687", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KVGDDCT", "url": "https://omabrowser.org/oma/group/KVGDDCT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EYT5", "url": "https://www.orthodb.org/?gene=E7EYT5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21029", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21029", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "NP_001314844", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314844", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EYT5", "url": "https://www.uniprot.org/uniprotkb/E7EYT5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EYT5-1", "url": "https://www.uniprot.org/uniprotkb/E7EYT5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030728-1", "url": "https://zfin.org/ZDB-GENE-030728-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPLSNNKVADDGSSTQPLQEGKAMVDSLIKVVACYRHLASCVGGCTDSSSLRRDLRQTRERAQTLALSCRNHLTTRLRDKTLPEADRKEAEWLWVSFSSCLELLHADMSKVFAMAKHFSLANNSTMVQTGIQGGATEVAARALSLPDLQEAGAGTQTSSVEGQEQSQLEQEIAQVDRTLDDMEMKVNVLRWTVEAVGPQYTDPVSTDSTSLALLSMDEEAAQSFCSRSQMFAAMMLCGVAMFAVVLSVCVVFLV", "length": 254, "header": "tr|E7EYT5-1|E7EYT5_DANRE Isoform 1 of Regulator of G-protein signaling 9-binding protein OS=Danio rerio OX=7955 GN=rgs9bp PE=3 SV=1 CANONICAL=E7EYT5-1" }, "isoforms": [ { "isoform_ac": "E7EYT5-1", "url": "https://www.uniprot.org/uniprotkb/E7EYT5/entry#E7EYT5-1", "sequence": { "sequence": "MPLSNNKVADDGSSTQPLQEGKAMVDSLIKVVACYRHLASCVGGCTDSSSLRRDLRQTRERAQTLALSCRNHLTTRLRDKTLPEADRKEAEWLWVSFSSCLELLHADMSKVFAMAKHFSLANNSTMVQTGIQGGATEVAARALSLPDLQEAGAGTQTSSVEGQEQSQLEQEIAQVDRTLDDMEMKVNVLRWTVEAVGPQYTDPVSTDSTSLALLSMDEEAAQSFCSRSQMFAAMMLCGVAMFAVVLSVCVVFLV", "length": 254, "header": "tr|E7EYT5-1|E7EYT5_DANRE Isoform 1 of Regulator of G-protein signaling 9-binding protein OS=Danio rerio OX=7955 GN=rgs9bp PE=3 SV=1 CANONICAL=E7EYT5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "R9AP, a membrane anchor for the photoreceptor GTPase accelerating protein, RGS9-1.", "journal": "Proc. Natl. Acad. Sci. U.S.A.", "date": "2002", "authors": "Hu G, Wensel TG", "evidence": [ { "database": "UniProtKB", "id": "E7EYT5", "url": "https://www.uniprot.org/uniprotkb/E7EYT5" } ], "reference": [ { "type": "PubMed", "id": "12119397", "url": "https://glygen.org/publication/PubMed/12119397" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7EYT5", "url": "https://www.uniprot.org/uniprotkb/E7EYT5" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:562687", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:562687", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M2BH52-1", "protein_name": "Regulator of G-protein signaling 9-binding protein", "gene_name": "si:ch73-167i17.6", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGKDECKTMLDALNKVTACYRHLVTALGSTSDSQNLREELKKTRKKAQELAVANRTKLTALLKDKSISKDDRAEYERLWVLFTSSMELLEVDMKRSLEIGQDFPLKVPTRHLIQTGMTGSTTTVAARAMSVQNMKYEADANIDTVDLRELETEIAQVDQMMEEMEMKVQVAPWAVEAKQEAGAELKSTVSVGNSSVGVISICEEEPKETVEGENGTMKIFAGIIFTAVLLIAGILGYLVINL", "length": 242 }, "evidence": [ { "id": "MGI:2384418", "url": "https://alliancegenome.org/gene/MGI:2384418#orthology", "database": "AGR" }, { "id": "HGNC:30304", "url": "https://alliancegenome.org/gene/HGNC:30304#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "D3ZC97-1", "protein_name": "Regulator of G protein signaling 9 binding protein", "gene_name": "Rgs9bp", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAREECKALLDALNKTTACYHHLVLTVGGSADTQDLREELQKTRQKARELAMATGSRLTVALRDRSLATEERAEFERLWVAFSGCLDLLEADMQRALALGAAFPLHAPRRPLVRTGVAGGSSAVAARALSARSLRHEAESDFDVADLPQLEREVLQVGEMIDNMEMKVNVPRWTVQARQSAGAELLSGASAGASSAGGISVEERAGPCDPSRALAATVFSAVLLVAVALALCVAKLS", "length": 237 }, "evidence": [ { "id": "MGI:2384418", "url": "https://alliancegenome.org/gene/MGI:2384418#orthology", "database": "AGR" }, { "id": "HGNC:30304", "url": "https://alliancegenome.org/gene/HGNC:30304#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q148R9-1", "protein_name": "Regulator of G protein signaling 9-binding protein", "gene_name": "Rgs9bp", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAREECKALLDALNKTTACYHHLVLTVGGSADTQDLREELQKTRQKARELAVATGARLTVALRDRSLATEERAEFERLWVAFSGCLDLLEADMQRALALGATFPLHAPRRPLVRTGVTGGSSAVAARALSARSLRHEAESDFDVADLPQLEREVLQVGEMIDDMEMKVNVPRWTVQARQAAGAELLSGASAGASSAGGISVEERAGPCDPSKALAATVFSAVLLVAVALALCVAKLS", "length": 237 }, "evidence": [ { "id": "MGI:2384418", "url": "https://alliancegenome.org/gene/MGI:2384418#orthology", "database": "AGR" }, { "id": "HGNC:30304", "url": "https://alliancegenome.org/gene/HGNC:30304#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030728-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030728-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZS82-1", "protein_name": "Regulator of G protein signaling 9-binding protein", "gene_name": "RGS9BP", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAREECKALLDGLNKTTACYHHLVLTVGGSADSQNLRQELQKTRQKAQELAVSTCARLTAVLRDRGLAADERAEFERLWVAFSGCLDLLEADMRRALELGAAFPLHAPRRPLVRTGVAGASSGVAARALSTRSLRLEAEGDFDVADLRELEREVLQVGEMIDNMEMKVNVPRWTVQARQAAGAELLSTVSAGPSSVVSLQERGGGCDPRKALAAILFGAVLLAAVALAVCVAKLS", "length": 235 }, "evidence": [ { "id": "MGI:2384418", "url": "https://alliancegenome.org/gene/MGI:2384418#orthology", "database": "AGR" }, { "id": "HGNC:30304", "url": "https://alliancegenome.org/gene/HGNC:30304#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030728-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030728-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "negative regulation of signal transduction", "id": "GO:0009968", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0009968", "evidence": [ { "database": "UniProtKB", "id": "E7EYT5", "url": "https://www.uniprot.org/uniprotkb/E7EYT5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 122, "end_pos": 124, "annotation": "n_glycosylation_sequon" }, { "start_pos": 123, "end_pos": 125, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 122, "end_pos": 124 }, { "start_pos": 123, "end_pos": 125 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { 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"field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7EYU1-1", "uniprot_ac": "E7EYU1", "uniprot_id": "E7EYU1_DANRE", "mass": { "chemical_mass": 26368.0, "monoisotopic_mass": 26368.0 }, "refseq": { "ac": "XP_003200427", "name": "transmembrane protein 179", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200427" }, "gene_names": [ { "name": "tmem179ab", "type": "recommended", "evidence": [ { "id": "E7EYU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYU1" } ] }, { "name": "tmem179ab", "type": "synonym", "evidence": [ { "id": "XP_003200427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200427" } ] } ], "protein_names": [ { "name": "Transmembrane protein 179", "type": "synonym", "evidence": [ { "id": "E7EYU1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYU1/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 179", "type": "synonym", "evidence": [ { "id": "XP_003200427", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200427" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003200427", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200427" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EYU1", "url": "https://www.uniprot.org/uniprotkb/E7EYU1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tmem179ab", "url": "https://www.uniprot.org/uniprotkb/E7EYU1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-190109-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-190109-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000090064", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000090064", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100537383", "url": "https://www.ncbi.nlm.nih.gov/gene/100537383", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029673", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029673", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR059010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR059010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100537383", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100537383", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DEFRGHC", "url": "https://omabrowser.org/oma/group/DEFRGHC/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EYU1", "url": "https://www.orthodb.org/?gene=E7EYU1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31872", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31872", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31872:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31872:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF26158", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF26158", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003200427", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200427", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EYU1", "url": "https://www.uniprot.org/uniprotkb/E7EYU1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EYU1-1", "url": "https://www.uniprot.org/uniprotkb/E7EYU1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-190109-1", "url": "https://zfin.org/ZDB-GENE-190109-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAMDNFIFAQCILYFLAFVFAFIAIVPLSENTEDFRGKCLLFTRGMWQNENITVSKQRFIIEEWGPQSSCSFITAVAIASLILSAVQAWRLLFFICKGHDDSIFNAFLNLLISTFVVFAVFLSSTIVSVGFNLWCDAITEGGSMHSSCEDLQDTDLELGLDNSAFYDQFAIAQFGLWAAWLTWLGITIVAFLKVYHNYRQEDLVDSLIHEKEFLLGRSSRRGSDVVHDKSGMI", "length": 233, "header": "tr|E7EYU1-1|E7EYU1_DANRE Isoform 1 of Transmembrane protein 179 OS=Danio rerio OX=7955 GN=tmem179ab PE=3 SV=1 CANONICAL=E7EYU1-1" }, "isoforms": [ { "isoform_ac": "E7EYU1-1", "url": "https://www.uniprot.org/uniprotkb/E7EYU1/entry#E7EYU1-1", "sequence": { "sequence": "MAMDNFIFAQCILYFLAFVFAFIAIVPLSENTEDFRGKCLLFTRGMWQNENITVSKQRFIIEEWGPQSSCSFITAVAIASLILSAVQAWRLLFFICKGHDDSIFNAFLNLLISTFVVFAVFLSSTIVSVGFNLWCDAITEGGSMHSSCEDLQDTDLELGLDNSAFYDQFAIAQFGLWAAWLTWLGITIVAFLKVYHNYRQEDLVDSLIHEKEFLLGRSSRRGSDVVHDKSGMI", "length": 233, "header": "tr|E7EYU1-1|E7EYU1_DANRE Isoform 1 of Transmembrane protein 179 OS=Danio rerio OX=7955 GN=tmem179ab PE=3 SV=1 CANONICAL=E7EYU1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100537383", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100537383", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B4Q1-1", "protein_name": "Transmembrane protein 179", "gene_name": "TMEM179", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MALDNFLFAQCVCYFLAFLFSFVVVVPLSEHGHDFRGRCLLFTEGMWLSANLTVQERERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFLHAFLSLLVSAFVLFLVFIASTIVSVGFTMWCDAITEKGTVPHSCEELQDIDLELNVDNSAFYDQFAIAQFGLWASWLAWLAITILAFLKVYHDYRQEDLLDSLTHEKELLLARPTSRGSFQDEKSAVI", "length": 233 }, "evidence": [ { "id": "E7EYU1", "url": "https://omabrowser.org/oma/group/E7EYU1/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A8V0Z016-1", "protein_name": "Transmembrane protein 179", "gene_name": "TMEM179", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MALSNFLFAQCICYFLAFLFSFIVVVPLSENGNDFHGRCLLFTEGMWLNANLTVERQRFTVQEWGPEAACRFSIFTGLLSLLLATVQAWRTLFFLCKGHEDSFFYAFLNLLISAFVVFITFIASTIVSVGFNMWCDAITEKGSMPNSCEELQDIDLELNLENSAFYDQFAVAQFGLWAAWLTWLGITILAFLKVYQNYRQEDLLDSLIHEKELLLGRSSSRTSLQDEKSAMI", "length": 232 }, "evidence": [ { "id": "E7EYU1", "url": "https://omabrowser.org/oma/group/E7EYU1/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "E9PU04-1", "protein_name": "Transmembrane protein 179", "gene_name": "Tmem179", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MALNNFLFAQCVCYFLAFLFSFVVVVPLSENGHDFRGRCLLFTEGMWLSANLTMQGRERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFFYAFLNLLVSAFVVFLVFIASTIVSVGFTMWCDTITEKGSAPHSCEEFQETDLELNVDNSAFYHQFAIAQFGLWASWLAWLAITTLAFLKVYHNYRQEDLLDSLVHEKELLLARPASRTSFQGEKSAVI", "length": 233 }, "evidence": [ { "id": "E7EYU1", "url": "https://omabrowser.org/oma/group/E7EYU1/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G5E584-1", "protein_name": "Transmembrane protein 179", "gene_name": "TMEM179", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MALNNFLFAQCVCYFLAFLFSFVVVVPLSENGHDFRGRCLLFTEGMWLSANLTVQERERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFLYAFLNLLVSAFVVFLVFIASTIVSVGFTMWCDTITEKGTVPHSCEELQGIDLELNVDNSAFYDQFAIAQFGLWASWLAWLAITVLAFLKVYHNYRQEDLLDSLVHEKELLLARPAPRAAFQEKSAVI", "length": 232 }, "evidence": [ { "id": "E7EYU1", "url": "https://omabrowser.org/oma/group/E7EYU1/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q6ZVK1-1", "protein_name": "Transmembrane protein 179", "gene_name": "TMEM179", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALNNFLFAQCACYFLAFLFSFVVVVPLSENGHDFRGRCLLFTEGMWLSANLTVQERERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFFSAFLNLLVSAFVVFLVFIASTIVSVGFTMWCDTITEKGTVPHSCEELQDIDLELGVDNSAFYDQFAIAQFGLWASWLAWLAITTLAFLKVYHNYRQEDLLDSLIHEKELLLARPSPRTSFQEEKSAVI", "length": 233 }, "evidence": [ { "id": "E7EYU1", "url": "https://omabrowser.org/oma/group/E7EYU1/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BHH9-1", "protein_name": "Transmembrane protein 179", "gene_name": "Tmem179", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MALNNFLFAQCVCYFLAFLFSFVVVVPLSENGHDFRGRCLLFTEGMWLSANLTMQGRERFTVQEWGPPAACRFSLLASLLSLLLAAAHAWRTLFFLCKGHEGSFFYAFLNLLVSAFVVFLVFIASTIVSVGFTMWCDTITEKGSTPHSCEEFQETDLELNVDNSAFYHQFAIAQFGLWASWLAWLAITTLAFLKVYHNYRQEDLLDSLVHEKELLLARPTSRTSFQGEKSAVI", "length": 233 }, "evidence": [ { "id": "E7EYU1", "url": "https://omabrowser.org/oma/group/E7EYU1/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VCF1-1", "protein_name": "Transmembrane protein 179", "gene_name": "Dmel\\CG13603", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MALANVLQLSQIAGHVILFILSLCIVVPLFINLDQFCGHCLLFTTGKWREEDGMFDVQWASNGFCNFPLITGFFLLIISVVQIYRYARMKEEASFIALFIDVVLGIWMLAMSILSAIFITLGFIVWCDSMTERFPSCAISAGQNIIHGDTEKINTSGFYIEMGTTQFGAWGSFAISVGIAVIALLKLIDNHQVRNIKVSMYLERQRLVNQQQYDGRSTPPIVSNASSDTEQNK", "length": 233 }, "evidence": [ { "id": "E7EYU1", "url": "https://omabrowser.org/oma/group/E7EYU1/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7EYU1", "url": "https://www.uniprot.org/uniprotkb/E7EYU1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 51, "end_pos": 53, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 51, "end_pos": 53 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EYV9-1", "uniprot_ac": "E7EYV9", "uniprot_id": "E7EYV9_DANRE", "mass": { "chemical_mass": 115709.0, "monoisotopic_mass": 115709.0 }, "refseq": { "ac": "XP_005157262", "name": "coiled-coil domain-containing protein 142", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157262" }, "gene_names": [ { "name": "ccdc142", "type": "recommended", "evidence": [ { "id": "E7EYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYV9" } ] }, { "name": "ccdc142", "type": "synonym", "evidence": [ { "id": "XP_005157262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157262" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 142", "type": "synonym", "evidence": [ { "id": "E7EYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYV9/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 142", "type": "synonym", "evidence": [ { "id": "XP_005157262", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157262" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005157262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157262" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EYV9", "url": "https://www.uniprot.org/uniprotkb/E7EYV9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ccdc142", "url": "https://www.uniprot.org/uniprotkb/E7EYV9", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-6705", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6705", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000101377", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000101377", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "569287", "url": "https://www.ncbi.nlm.nih.gov/gene/569287", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026700", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026700", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR055350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR055350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:569287", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569287", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "TWEQLQH", "url": "https://omabrowser.org/oma/group/TWEQLQH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EYV9", "url": "https://www.orthodb.org/?gene=E7EYV9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21436", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21436", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21436:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21436:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF14923", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14923", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005157262", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005157262", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EYV9", "url": "https://www.uniprot.org/uniprotkb/E7EYV9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EYV9-1", "url": "https://www.uniprot.org/uniprotkb/E7EYV9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-6705", "url": "https://zfin.org/ZDB-GENE-030131-6705", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAHSSGSSQDGQTDSKTESHTQAVPDKTDSSAAESPENQHCDNGQRPSYYSEILPDEYISNEKFDASWYQSSFTKSLQRAEALFRNRLNPSLKRLMRQKSKDGSWESESESIGSCSSRSIQRLGETLQNLSSQCHILHDPAGGRSFGCIRGLSSSEEEEFYYHPQAAAFTQHYCQLQHLMDQRAQLLFFHEYARRTQMATCFVAQLGSVLEKTQLLLPDKGQVTEQPNSTWNLNLRALCQEMQVHVSHWDLLWAKAHSDLRLRRALFSRIETLSSMQRTLCLLALQAMQLLEQCIYTALLALTAAQLDRVPRDALVDLLCAVELYNEIVEDTESQCKTSTQSSKLMFNSDWPQLGSSTIRKATGPTIFPVEQLMMILAQSRAQKVAKQLYTWASQQSNLLLANNPKELKGHTKLNSRLLSSPTINLHTVQLEPQAAVEDTPQSPLHKLWSSNLPFSLFISRDRACLDTLFKVLVTSTNLLAPHIPKKPPLDRTVDLEDSVVICRRASDGEEKLLNRPRMSSRAHDAAAVDLRKSDACVKLFSNYKNLLWKQFGKAVIRHFYYQPYNSTLGSINQWNDEMLLLLVSWLKHSYFEDLIPEECKESLSDFCFYLLSTAAFTQWDEMKCLSLGSGLKEKCVPGAKLEGCAIRTATMDLILQLFLPLHTVLQLLQHPDIESGDIESKSLKRNHLALLCRSVATVHSSTIWVMSKAFQFLASWSITKFLLVTQGDLKDLKDSVESLVHLTRAVIRDSAVHPLIVQQTDSLSKALTELQAFSDLVLRTFTMDCKKMSTEIFEQTMPSARHWRINHKTELPSSPSDYAACAVQSVIGQVLEGVQPLPDNARVPALTEAMTAFMEAWMEHILKQKIKFSIQGALQLKQDFDLIRDMIRSEEYSLSEELHQKLLSLRVFHQVDNAIVCLLQQPMAKPYLPSRGWEPFRHCCPNSAQVMDQAAAGSLNNLESMDIQAACQQALTQAESSLTPELLSSTPQESYLAAAQQEWLDLRIHSGSRWKLPVLQCFTRSEP", "length": 1024, "header": "tr|E7EYV9-1|E7EYV9_DANRE Isoform 1 of Coiled-coil domain-containing protein 142 OS=Danio rerio OX=7955 GN=ccdc142 PE=4 SV=1 CANONICAL=E7EYV9-1" }, "isoforms": [ { "isoform_ac": "E7EYV9-1", "url": "https://www.uniprot.org/uniprotkb/E7EYV9/entry#E7EYV9-1", "sequence": { "sequence": "MAHSSGSSQDGQTDSKTESHTQAVPDKTDSSAAESPENQHCDNGQRPSYYSEILPDEYISNEKFDASWYQSSFTKSLQRAEALFRNRLNPSLKRLMRQKSKDGSWESESESIGSCSSRSIQRLGETLQNLSSQCHILHDPAGGRSFGCIRGLSSSEEEEFYYHPQAAAFTQHYCQLQHLMDQRAQLLFFHEYARRTQMATCFVAQLGSVLEKTQLLLPDKGQVTEQPNSTWNLNLRALCQEMQVHVSHWDLLWAKAHSDLRLRRALFSRIETLSSMQRTLCLLALQAMQLLEQCIYTALLALTAAQLDRVPRDALVDLLCAVELYNEIVEDTESQCKTSTQSSKLMFNSDWPQLGSSTIRKATGPTIFPVEQLMMILAQSRAQKVAKQLYTWASQQSNLLLANNPKELKGHTKLNSRLLSSPTINLHTVQLEPQAAVEDTPQSPLHKLWSSNLPFSLFISRDRACLDTLFKVLVTSTNLLAPHIPKKPPLDRTVDLEDSVVICRRASDGEEKLLNRPRMSSRAHDAAAVDLRKSDACVKLFSNYKNLLWKQFGKAVIRHFYYQPYNSTLGSINQWNDEMLLLLVSWLKHSYFEDLIPEECKESLSDFCFYLLSTAAFTQWDEMKCLSLGSGLKEKCVPGAKLEGCAIRTATMDLILQLFLPLHTVLQLLQHPDIESGDIESKSLKRNHLALLCRSVATVHSSTIWVMSKAFQFLASWSITKFLLVTQGDLKDLKDSVESLVHLTRAVIRDSAVHPLIVQQTDSLSKALTELQAFSDLVLRTFTMDCKKMSTEIFEQTMPSARHWRINHKTELPSSPSDYAACAVQSVIGQVLEGVQPLPDNARVPALTEAMTAFMEAWMEHILKQKIKFSIQGALQLKQDFDLIRDMIRSEEYSLSEELHQKLLSLRVFHQVDNAIVCLLQQPMAKPYLPSRGWEPFRHCCPNSAQVMDQAAAGSLNNLESMDIQAACQQALTQAESSLTPELLSSTPQESYLAAAQQEWLDLRIHSGSRWKLPVLQCFTRSEP", "length": 1024, "header": "tr|E7EYV9-1|E7EYV9_DANRE Isoform 1 of Coiled-coil domain-containing protein 142 OS=Danio rerio OX=7955 GN=ccdc142 PE=4 SV=1 CANONICAL=E7EYV9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:569287", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:569287", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2KB94-1", "protein_name": "Coiled-coil domain containing 142", "gene_name": "Ccdc142", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MARASRSSGLLPPITNVPPSWAQPLGDGEERGKGKRGGLELLAAMSAPCPDSGRQPWAPESASGPMPFALQRLRAELLRLHREREQLLRARDCARHLQAVVRLLRSGSSAGSFSLQQLHGDLQMCPSRRAAQRLGFPGSRETLLLARPVGLAAQHLDANIEMQLRTLGRAPASLGLTSQLAELLLALPFYHTLQGQSLSFVPGAARPFPAARVLHLLAAERGCQVADRLAEALGRSGLQDQLRRQCDQERELLPGLLGLIGGVASRDSSGLRLGGPGALWSQYWTMLWAACAQSLDLRVGPWGDPKAVAQQLSQALCQASLPQECEKELLSLCHSLFHRSLVCSWDQGFCQALGSAVGGQSSPASPSTAELLQRLFPPLLDILRQPRPELSLCQPAGPTPVALGLCTLQTTLLWFLGKAQQHLAAWAPGPFLLLIQKDLPPLLHAVEALSSLASEAAFSLEVEQQLGLEIQKLTARMQLLPKESLSLFFQECHKQATQGFKLHMPRGGYWRLRLCPEHPSDPSEYARVVVYTVLEPVLQGLRGLPPEAQAPALSQALTATLGAWLDHILTHGIRFSLQGALQLKQDFGVVREVLEQEQWGLSPELRQTLLSLSIFQQLDGALLCLLQQPLPKNPVQRRPHRCCFCNEVQTIELPTSSLNSLESLAPPLRPGVSPAQNTHLLSTLGGGGRGGGGGGPSPEAYLAGNQQAWLALRLHQHPRWHLPFFSCLGTSPEP", "length": 734 }, "evidence": [ { "id": "HGNC:25889", "url": "https://alliancegenome.org/gene/HGNC:25889#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6705", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6705#orthology", "database": "AGR" }, { "id": "MGI:3045292", "url": "https://alliancegenome.org/gene/MGI:3045292#orthology", "database": "AGR" }, { "id": "RGD:1561779", "url": "https://alliancegenome.org/gene/RGD:1561779#orthology", "database": "AGR" }, { "id": "FB:FBgn0039009", "url": "https://alliancegenome.org/gene/FB:FBgn0039009#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q17RM4-1", "protein_name": "Coiled-coil domain-containing protein 142", "gene_name": "CCDC142", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAQASRSGSLPPLVIVPPLRAQPGGTGEEQWERSRTGGLRWEVHCWPSGTSGGTPWWPTPADVSEDYEADAAAWRRGPAGGGPIPPALQRLRAVLLRLHREREQLLQARDCAYHLQSAVRLMKTLSPGSPSGGPSPLPQWCRDLQLHPSQGAVLRIGPGETLEPLLLARPIGLAAQCLEAVIEMQLRALGREPASPGLSSQLAELLFALPAYHTLQRKALSHVPGAARPFPTSRVLRLLTGERGCQVASRLDEALQGSALRDQLRRRCQEEGDLLPGLLGLVGGVAGSASCGLGLGGAGALWSQYWTLLWAACAQSLDLNLGPWRDPRATAQQLSQALGQASLPQECEKELASLCHRLLHQSLIWSWDQGFCQALGSALGGQSSLPTSSGTAELLQQLFPPLLDALREPRLRRIFCQPADPAPVALGLCTLQTTLLWFLGRAQQYLAAWDPASFLLLIQKDLPPLLHEAEALYSLASEESLALEVEQQLGLEIQKLTAQIQLLPEESLSVFSQECHKQAMQGFKLYMPRGRYWRLRLCPEPPSAPSEYAGLVVRTVLEPVLQGLQGLPPQAQAPALGQALTAIVGAWLDHILTHGIRFSLQGALQLKQDFGVVRELLEEEQWSLSPDLRQTLLMLSIFQQLDGALLCLLQQPLPKSQVHRRPPCCCACQEVQTTKLPSSCLNSLESLEPPLQPGTSPAQTGQLQSTLGGRGPSPEGYLVGNQQAWLALRQHQRPRWHLPFFSCLGTSPES", "length": 750 }, "evidence": [ { "id": "HGNC:25889", "url": "https://alliancegenome.org/gene/HGNC:25889#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6705", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6705#orthology", "database": "AGR" }, { "id": "MGI:3045292", "url": "https://alliancegenome.org/gene/MGI:3045292#orthology", "database": "AGR" }, { "id": "RGD:1561779", "url": "https://alliancegenome.org/gene/RGD:1561779#orthology", "database": "AGR" }, { "id": "FB:FBgn0039009", "url": "https://alliancegenome.org/gene/FB:FBgn0039009#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CAI1-1", "protein_name": "Coiled-coil domain-containing protein 142", "gene_name": "Ccdc142", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MARASSSSGPLPPLANVPSSWAQPVGAGEERDEGRRGGLGLLAAVSVPCPDFSRQPWAPASASGPMPFALQRLRATLLRLHREREQLLRARDCARHLQAVVRLLRSGSSAGSLSLQQLHGDLQLCPSRGAALRLGFPGSRETLLLTRPVGLAAQHLEAAIEMQLRSLGRTPASLGLTSQLAELLLALPFYHTLQGHSLNFVPGAARPFPAARVLQLLAAERGCQVADKLAEARGGSGLQEQLRRQCEQERELLPGLLGLVGGVASTDSSGLRLGGPGALWSQYWTLLWAACAKCLDLRVGPWEDPRAMAQELSQALCQAPLPQECEKELLSLCHSLFHQSVICSWDQGFCQALGSALGGQSSPASLSPTSELLQRLFPPLLDSLRQPRPELRLCPPAGPTPVALGLCTLQTTLLWFVGRAQQHLAAWDPGSFLLLLQKDLPPLLSAVEALSSLASEAALTLEVEQQLGLEIHNLTEKMQLLPKESLGLFVQECHKQATQGFKLHMPRGRYWRLRLCPEPPSDPSEYARIVVYSVLEPVLQGLQGLPPEAQAPALGQALTATLGAWLDHILTHGIRFSLQGALQLKQDFGVVREVLEQEQWGLSQELRQTLLSLSIFQQLDGALLCLLQQPLPKNPVHRRPPRCCLCYEVQTTELPTSSLNSLENLAPPLRLGVSPAQNTHLLSTLGGGGRGGGGGGGPGPSPEAYLVGNQQAWLALRLHQHPRWHLPFFSCLRTSPEP", "length": 738 }, "evidence": [ { "id": "HGNC:25889", "url": "https://alliancegenome.org/gene/HGNC:25889#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6705", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6705#orthology", "database": "AGR" }, { "id": "MGI:3045292", "url": "https://alliancegenome.org/gene/MGI:3045292#orthology", "database": "AGR" }, { "id": "RGD:1561779", "url": "https://alliancegenome.org/gene/RGD:1561779#orthology", "database": "AGR" }, { "id": "FB:FBgn0039009", "url": "https://alliancegenome.org/gene/FB:FBgn0039009#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VCV8-1", "protein_name": "Coiled-coil protein 142 C-terminal domain-containing protein", "gene_name": "Dmel\\CG13842", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSTTPKWYCRNKSQPMHTFAEIGKLGLELRRITKRIVIDVNSAIFSEHDTILEECERVVEQYWNLKDETKNADFQSLSKKIKRSPYNQLLMKKFHLIMDLNDRRFCQLTFVLKRTLSFLLRKSMQSEMWLNWALHITQLYNKCRKVEKPLVPVEVDKPPGDEELEEEPKLSGKRKEEMPANVCSNMYPALLLALKSIDFGYVLQLVAQTRVEQNALDLVFGLFNMGEQDAWREQQNLESTSSSLEILRTLNISFAAGDYQPYCDSAQDYKSMQMQMAEESPQDQDRQSLRCKHTESFLQKERVFIAQLIAKATEISPTIFDNGKKGPVDMNAYIVKGLRLLWSYVGIILDHILLWWIDNPVSCYRLTHIDSIRSWLYHQSVNDIPEPVFSTLRGIGEILTGFVCNTIWDQLFRLTLISSNNTNRLVDVVAEQYRDCPKNEFGTPTGTVWISIFANLVNLSNQYFSNLEAHNNSSLMPVAEQIPILHRLDHSVHSMRLWVTEQAKLLCCEWKMDRFFQILEHDVKLCLNVFITFQLPKLTADLSDILMLVCVALRTKLIAEVNANIDKLKKTTDECVQILSAVCRVLSLANFTLCFPAASFWQREVYNNDEKSLYVGYVLDEIYLPTIRATKDIVILKLILKLICEAWLDFIYQKRIRFSVNGAVRLLNDFDDVREWILACSLLDEEQLDKLSNHEVLRMCKGVGKILLRKPEDVISITQSPKYDKKAQDASAQDTQLPSEMFVSNQKHWLQLRASGGNGFPFLKLCCGDIGM", "length": 772 }, "evidence": [ { "id": "HGNC:25889", "url": "https://alliancegenome.org/gene/HGNC:25889#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-6705", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-6705#orthology", "database": "AGR" }, { "id": "MGI:3045292", "url": "https://alliancegenome.org/gene/MGI:3045292#orthology", "database": "AGR" }, { "id": "RGD:1561779", "url": "https://alliancegenome.org/gene/RGD:1561779#orthology", "database": "AGR" }, { "id": "FB:FBgn0039009", "url": "https://alliancegenome.org/gene/FB:FBgn0039009#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 129, "end_pos": 131, "annotation": "n_glycosylation_sequon" }, { "start_pos": 228, "end_pos": 230, "annotation": "n_glycosylation_sequon" }, { "start_pos": 566, "end_pos": 568, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EYV9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYV9" }, { "id": "PF14923", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF14923" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Coiled-coil protein 142 C-terminal", "eco_id": "ECO_0000259", "start_pos": 547, "end_pos": 1001, "start_aa": "Leu", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 129, "end_pos": 131 }, { "start_pos": 228, "end_pos": 230 }, { "start_pos": 566, "end_pos": 568 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EYW4-1", "uniprot_ac": "E7EYW4", "uniprot_id": "E7EYW4_DANRE", "mass": { "chemical_mass": 50940.0, "monoisotopic_mass": 50940.0 }, "refseq": { "ac": "XP_003200019", "name": "uncharacterized protein si:dkeyp-121d2.7 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200019" }, "gene_names": [ { "name": "si:dkeyp-121d2.7", "type": "recommended", "evidence": [ { "id": "E7EYW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYW4" } ] }, { "name": "si:dkeyp-121d2.7", "type": "synonym", "evidence": [ { "id": "XP_003200019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200019" } ] } ], "protein_names": [ { "name": "Uncharacterized protein si:dkeyp-121d2.7 isoform X1", "type": "synonym", "evidence": [ { "id": "E7EYW4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYW4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein si:dkeyp-121d2.7 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_003200019", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200019" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003200019", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200019" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EYW4", "url": "https://www.uniprot.org/uniprotkb/E7EYW4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkeyp-121d2.7", "url": "https://www.uniprot.org/uniprotkb/E7EYW4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141215-52", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141215-52", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000086245", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000086245", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100536535", "url": "https://www.ncbi.nlm.nih.gov/gene/100536535", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100536535", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100536535", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "CHGSRTH", "url": "https://omabrowser.org/oma/group/CHGSRTH/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EYW4", "url": "https://www.orthodb.org/?gene=E7EYW4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14003:SF23", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14003:SF23", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_003200019", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200019", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58H8V5", "url": "https://www.uniprot.org/uniprotkb/A0AC58H8V5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58H8V5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58H8V5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EYW4", "url": 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0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EYW5-1", "uniprot_ac": "E7EYW5", "uniprot_id": "E7EYW5_DANRE", "mass": { "chemical_mass": 11201.0, "monoisotopic_mass": 11201.0 }, "refseq": { "ac": "NP_001303248", "name": "cystatin 14a, tandem duplicate 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303248" }, "gene_names": [ { "name": "cst14a.1", "type": "recommended", "evidence": [ { "id": "E7EYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYW5" } ] }, { "name": "cst14a.1", "type": "synonym", "evidence": [ { "id": "NP_001303248", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303248" } ] }, { "name": 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supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000024.1. On Oct 13, 2015 this sequence version replaced XP_698401.1. Transcript Variant: This variant (1) represents the shorter transcript and encodes the supported protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001303248", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303248" } ] } ], "disease": [ { "disease_id": "DOID:0070523", "recommended_name": { "id": "DOID:0070523", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070523", "name": "peeling skin syndrome 4", "description": "A peeling skin syndrome that has_material_basis_in homozygous mutation in the CSTA gene on chromosome 3q21.1." }, "synonyms": [ { "id": "DOID:0070523", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070523", "name": "PSS4", "description": "" }, { "id": "DOID:0070523", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070523", "name": "ichthyosis bullosa of Siemens-like", "description": "" }, { "id": "MONDO:0011937", "resource": "MONDO", "url": 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"https://www.uniprot.org/uniprotkb/E7EYW5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cst14a.1", "url": "https://www.uniprot.org/uniprotkb/E7EYW5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000028164", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000028164", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00042", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00042", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "573769", "url": "https://www.ncbi.nlm.nih.gov/gene/573769", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000010", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000010", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001713", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001713", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018073", "url": "https://www.ebi.ac.uk/interpro/entry/IPR018073", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR046350", "url": "https://www.ebi.ac.uk/interpro/entry/IPR046350", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:573769", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:573769", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "LPHENQP", "url": "https://omabrowser.org/oma/group/LPHENQP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EYW5", "url": "https://www.orthodb.org/?gene=E7EYW5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11414", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11414", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR11414:SF21", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11414:SF21", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00031", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00031", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-6798695", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6798695", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "NP_001303248", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001303248", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EYW5", "url": "https://www.uniprot.org/uniprotkb/E7EYW5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EYW5-1", "url": "https://www.uniprot.org/uniprotkb/E7EYW5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-141031-1", "url": "https://zfin.org/ZDB-GENE-141031-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MPLVRGGTSEAKDANEEVQKICDKMKADAEEKAGRKFDVFTAKSFKTQVVAGTNYFVKVHVGDEDYVHLRVYKTLPHAGETLQLTSIQTAKAHHDAIEYF", "length": 100, "header": "tr|E7EYW5-1|E7EYW5_DANRE Isoform 1 of Cystatin-B OS=Danio rerio OX=7955 GN=cst14a.1 PE=1 SV=1 CANONICAL=E7EYW5-1" }, "isoforms": [ { "isoform_ac": "E7EYW5-1", "url": "https://www.uniprot.org/uniprotkb/E7EYW5/entry#E7EYW5-1", "sequence": { "sequence": "MPLVRGGTSEAKDANEEVQKICDKMKADAEEKAGRKFDVFTAKSFKTQVVAGTNYFVKVHVGDEDYVHLRVYKTLPHAGETLQLTSIQTAKAHHDAIEYF", "length": 100, "header": "tr|E7EYW5-1|E7EYW5_DANRE Isoform 1 of Cystatin-B OS=Danio rerio OX=7955 GN=cst14a.1 PE=1 SV=1 CANONICAL=E7EYW5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7EYW5", "url": "https://www.uniprot.org/uniprotkb/E7EYW5" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Evolution of complexity in the zebrafish synapse proteome.", "journal": "Nat. Commun.", "date": "2017", "authors": "Bayes A, Collins MO, Reig-Viader R, Gou G, Goulding D, Izquierdo A, Choudhary JS, Emes RD, Grant SG", "evidence": [ { "database": "UniProtKB", "id": "E7EYW5", "url": "https://www.uniprot.org/uniprotkb/E7EYW5" } ], "reference": [ { "type": "PubMed", "id": "28252024", "url": "https://glygen.org/publication/PubMed/28252024" } ] } ], "pathway": [ { "id": "dre:573769", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:573769", "resource": "KEGG Pathway" }, { "id": "R-DRE-6798695", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6798695", "resource": "Reactome", "description": "Neutrophil degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A2R8QDV2-1", "protein_name": "Cystatin-B", "gene_name": "cst14b.1", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MATKKVGGQSEEKQATPEVQKICDEVKHQAEEKAGKKFTAFTAILFTTQVVAGTNYFIKVNVGGDQFIHLRVHKPLPHAGDKVQLQGIQVSKSCQDPIHYF", "length": 101 }, "evidence": [ { "id": "HGNC:2482", "url": "https://alliancegenome.org/gene/HGNC:2482#orthology", "database": "AGR" }, { "id": "RGD:41304704", "url": "https://alliancegenome.org/gene/RGD:41304704#orthology", "database": "AGR" }, { "id": "RGD:1594822", "url": "https://alliancegenome.org/gene/RGD:1594822#orthology", "database": "AGR" }, { "id": "RGD:6491049", "url": "https://alliancegenome.org/gene/RGD:6491049#orthology", "database": "AGR" }, { "id": "RGD:1303106", "url": "https://alliancegenome.org/gene/RGD:1303106#orthology", "database": "AGR" }, { "id": "RGD:2435", "url": "https://alliancegenome.org/gene/RGD:2435#orthology", "database": "AGR" }, { "id": "RGD:1560676", "url": "https://alliancegenome.org/gene/RGD:1560676#orthology", "database": "AGR" }, { "id": "RGD:1307831", "url": "https://alliancegenome.org/gene/RGD:1307831#orthology", "database": "AGR" }, { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:106197", "url": "https://alliancegenome.org/gene/MGI:106197#orthology", "database": "AGR" }, { "id": "MGI:106196", "url": "https://alliancegenome.org/gene/MGI:106196#orthology", "database": "AGR" }, { "id": "MGI:106198", "url": "https://alliancegenome.org/gene/MGI:106198#orthology", "database": "AGR" }, { "id": "MGI:3524930", "url": "https://alliancegenome.org/gene/MGI:3524930#orthology", "database": "AGR" }, { "id": "MGI:109514", "url": "https://alliancegenome.org/gene/MGI:109514#orthology", "database": "AGR" }, { "id": "MGI:3696881", "url": "https://alliancegenome.org/gene/MGI:3696881#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A8I6GJV2-1", "protein_name": "Stefin A2-like 2", "gene_name": "Stfa2l2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQEPLRTVGGLSEARPATAEIQEIADKVKPLLEKKTNGKYEKFEAVQYKVQVVAGLNYFIKVDVGCGCYVHLRVFSGISRENDLELHGYQTNKSKNDELTYF", "length": 103 }, "evidence": [ { "id": "RGD:1560676", "url": "https://alliancegenome.org/gene/RGD:1560676#orthology", "database": "AGR" }, { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:106197", "url": "https://alliancegenome.org/gene/MGI:106197#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8I6GLK6-1", "protein_name": "Cystatin domain-containing protein", "gene_name": "Stfa2l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLGGLSEARTATPEIQKIADKVRSQLEENTNEKYEKFEAVEYKTQFVAGQNYFIKMDVGCSGFLHIKVFSAHSGKDDLELHGYRTNKTKNDELTYF", "length": 97 }, "evidence": [ { "id": "RGD:1594822", "url": "https://alliancegenome.org/gene/RGD:1594822#orthology", "database": "AGR" }, { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:106198", "url": "https://alliancegenome.org/gene/MGI:106198#orthology", "database": "AGR" }, { "id": "MGI:3696881", "url": "https://alliancegenome.org/gene/MGI:3696881#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0L0K2-1", "protein_name": "Stefin A2-like 3", "gene_name": "Stfa2l3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDKGTPRIKGGLSEARPATAEIQEIADKVRPQLEEKTNEKYEKFEAVQYKVQVVAGNNYFIKVDVGCGCYLHLRVFSGISRENNLELHGYQTNKTENDELTSF", "length": 103 }, "evidence": [ { "id": "RGD:6491049", "url": "https://alliancegenome.org/gene/RGD:6491049#orthology", "database": "AGR" }, { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:106197", "url": "https://alliancegenome.org/gene/MGI:106197#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0ABK0M930-1", "protein_name": "Cystatin domain-containing protein", "gene_name": "LOC120095659", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MEQEPLRTVGGLSEARPATAEIQEIADKVKPLLEKKTNGKYEKFEAVQYKVQVVAGLNYFIKVDVGCGCYVHLRVFSGISKENELELHGYQTNKSKNEELTYF", "length": 103 }, "evidence": [ { "id": "RGD:41304704", "url": "https://alliancegenome.org/gene/RGD:41304704#orthology", "database": "AGR" }, { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:106197", "url": "https://alliancegenome.org/gene/MGI:106197#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "L7N257-1", "protein_name": "Cystatin domain containing 6", "gene_name": "Cstdc6", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MYGGVSEAKPATPEIQKIADKVRSQLEAKTNKKYEKFEAVEYKTQAVAGENIFIKMDVGHGCFIHIKVFSGPTGKDNYELHGYQTDKAKDDELTYF", "length": 96 }, "evidence": [ { "id": "RGD:1594822", "url": "https://alliancegenome.org/gene/RGD:1594822#orthology", "database": "AGR" }, { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:3696881", "url": "https://alliancegenome.org/gene/MGI:3696881#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P01039-1", "protein_name": "Cystatin-A", "gene_name": "Csta", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MDPGTTGIVGGVSEAKPATPEIQEVADKVKRQLEEKTNEKYEKFKVVEYKSQVVAGQILFMKVDVGNGRFLHMKVLRGLSGDDDLKLLDYQTNKTKNDELTDF", "length": 103 }, "evidence": [ { "id": "RGD:1307831", "url": "https://alliancegenome.org/gene/RGD:1307831#orthology", "database": "AGR" }, { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:106196", "url": "https://alliancegenome.org/gene/MGI:106196#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P01040-1", "protein_name": "Cystatin-A", "gene_name": "CSTA", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MIPGGLSEAKPATPEIQEIVDKVKPQLEEKTNETYGKLEAVQYKTQVVAGTNYYIKVRAGDNKYMHLKVFKSLPGQNEDLVLTGYQVDKNKDDELTGF", "length": 98 }, "evidence": [ { "id": "RGD:41304704", "url": "https://alliancegenome.org/gene/RGD:41304704#orthology", "database": "AGR" }, { "id": "RGD:1594822", "url": "https://alliancegenome.org/gene/RGD:1594822#orthology", "database": "AGR" }, { "id": "RGD:6491049", "url": "https://alliancegenome.org/gene/RGD:6491049#orthology", "database": "AGR" }, { "id": "RGD:1303106", "url": "https://alliancegenome.org/gene/RGD:1303106#orthology", "database": "AGR" }, { "id": "RGD:1560676", "url": "https://alliancegenome.org/gene/RGD:1560676#orthology", "database": "AGR" }, { "id": "RGD:1307831", "url": "https://alliancegenome.org/gene/RGD:1307831#orthology", "database": "AGR" }, { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:106197", "url": "https://alliancegenome.org/gene/MGI:106197#orthology", "database": "AGR" }, { "id": "MGI:106196", "url": "https://alliancegenome.org/gene/MGI:106196#orthology", "database": "AGR" }, { "id": "MGI:106198", "url": "https://alliancegenome.org/gene/MGI:106198#orthology", "database": "AGR" }, { "id": "MGI:3524930", "url": "https://alliancegenome.org/gene/MGI:3524930#orthology", "database": "AGR" }, { "id": "MGI:3696881", "url": "https://alliancegenome.org/gene/MGI:3696881#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P01041-1", "protein_name": "Cystatin-B", "gene_name": "Cstb", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MMCGAPSATMPATTETQEIADKVKSQLEEKANQKFDVFKAISFRRQVVAGTNFFIKVDVGEEKCVHLRVFEPLPHENKPLTLSSYQTDKEKHDELTYF", "length": 98 }, "evidence": [ { "id": "HGNC:2482", "url": "https://alliancegenome.org/gene/HGNC:2482#orthology", "database": "AGR" }, { "id": "RGD:2435", "url": "https://alliancegenome.org/gene/RGD:2435#orthology", "database": "AGR" }, { "id": "MGI:109514", "url": "https://alliancegenome.org/gene/MGI:109514#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P04080-1", "protein_name": "Cystatin-B", "gene_name": "CSTB", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MMCGAPSATQPATAETQHIADQVRSQLEEKENKKFPVFKAVSFKSQVVAGTNYFIKVHVGDEDFVHLRVFQSLPHENKPLTLSNYQTNKAKHDELTYF", "length": 98 }, "evidence": [ { "id": "HGNC:2482", "url": "https://alliancegenome.org/gene/HGNC:2482#orthology", "database": "AGR" }, { "id": "RGD:2435", "url": "https://alliancegenome.org/gene/RGD:2435#orthology", "database": "AGR" }, { "id": "MGI:109514", "url": "https://alliancegenome.org/gene/MGI:109514#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" }, { "id": "E7EYW5", "url": "https://omabrowser.org/oma/group/E7EYW5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P35173-1", "protein_name": "Stefin-3", "gene_name": "Stfa3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSQENLKIKGGLSEARPATPEIQMIADKVRPLLEEQTNEKYEKFEAVEYKSQVVAGQNLFIKIDVGNGCFLHMKVFRGLSGEDDLKLKGYQTNKTKTDELTSM", "length": 103 }, "evidence": [ { "id": "RGD:1303106", "url": "https://alliancegenome.org/gene/RGD:1303106#orthology", "database": "AGR" }, { "id": "RGD:1307831", "url": "https://alliancegenome.org/gene/RGD:1307831#orthology", "database": "AGR" }, { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:106196", "url": "https://alliancegenome.org/gene/MGI:106196#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35174-1", "protein_name": "Stefin-2", "gene_name": "Stfa2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MTEYTRKIKGGLSEARPATSEIQEIADKVRPLLEEKTNEKYEKFKAIEYKVQVVQGLNYFIKMNVGRGCYLHINVLSGISSENDLELTGYQTNKAKNDELTYF", "length": 103 }, "evidence": [ { "id": "RGD:41304704", "url": "https://alliancegenome.org/gene/RGD:41304704#orthology", "database": "AGR" }, { "id": "RGD:6491049", "url": "https://alliancegenome.org/gene/RGD:6491049#orthology", "database": "AGR" }, { "id": "RGD:1560676", "url": "https://alliancegenome.org/gene/RGD:1560676#orthology", "database": "AGR" }, { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:106197", "url": "https://alliancegenome.org/gene/MGI:106197#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P35175-1", "protein_name": "Stefin-1", "gene_name": "Stfa1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSLGGVSEASRATPEIQMIANKVRPQLEAKTNKKYEKFEAVEYKTQVVAGENIFIKMDVGHGCFIHIKVFNGPTGKDNYELHGYQTDKTMDEELTYF", "length": 97 }, "evidence": [ { "id": "RGD:1594822", "url": "https://alliancegenome.org/gene/RGD:1594822#orthology", "database": "AGR" }, { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:106198", "url": "https://alliancegenome.org/gene/MGI:106198#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "P56567-1", "protein_name": "Cystatin-A", "gene_name": "Csta", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MIPGGLTEARPATAEVQEIADRVKAQLEEETNEKYEIFKAVEYKTQVVAGVNYFIKMDVGGGCFTHIKVFKDLSGKNNLELTGYQTNKTEDDELTYF", "length": 97 }, "evidence": [ { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:3524930", "url": "https://alliancegenome.org/gene/MGI:3524930#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q62426-1", "protein_name": "Cystatin-B", "gene_name": "Cstb", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MMCGAPSATMPATAETQEVADQVKSQLESKENQKFDVFKAISFKRQIVAGTNLFIKVDVGGDKCVHLRVFQPLPHENKPLTLSSYQTNKERHDELSYF", "length": 98 }, "evidence": [ { "id": "HGNC:2482", "url": "https://alliancegenome.org/gene/HGNC:2482#orthology", "database": "AGR" }, { "id": "RGD:2435", "url": "https://alliancegenome.org/gene/RGD:2435#orthology", "database": "AGR" }, { "id": "MGI:109514", "url": "https://alliancegenome.org/gene/MGI:109514#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" }, { "id": "E7EYW5", "url": "https://omabrowser.org/oma/group/E7EYW5/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6IE17-1", "protein_name": "Stefin A2-like 1", "gene_name": "Stfa2l1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MNQDTIVITGGLSEARPATPEIQEIADKVKTLLEEKTNGKYEKFEAIQYKVQVVAGRNYFIKMDVGHGCFTHIKVFQGLSGKDDLELSGYQTNKTKNDELTHF", "length": 103 }, "evidence": [ { "id": "RGD:1303106", "url": "https://alliancegenome.org/gene/RGD:1303106#orthology", "database": "AGR" }, { "id": "HGNC:2481", "url": "https://alliancegenome.org/gene/HGNC:2481#orthology", "database": "AGR" }, { "id": "MGI:106196", "url": "https://alliancegenome.org/gene/MGI:106196#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141031-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141031-1#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E7EYW5", "url": "https://www.uniprot.org/uniprotkb/E7EYW5" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "immune system process", "id": "GO:0002376", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002376", "evidence": [ { "database": "UniProtKB", "id": "E7EYW5", "url": "https://www.uniprot.org/uniprotkb/E7EYW5" } ], "pmid": "" }, { "name": "cellular response to bacterial lipoprotein", "id": "GO:0071220", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0071220", "evidence": [ { "database": "UniProtKB", "id": "E7EYW5", "url": "https://www.uniprot.org/uniprotkb/E7EYW5" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "cysteine-type endopeptidase inhibitor activity", "id": "GO:0004869", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0004869", "evidence": [ { "database": "UniProtKB", "id": "E7EYW5", "url": "https://www.uniprot.org/uniprotkb/E7EYW5" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EYW5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EYW5" }, { "id": "SM00043", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00043" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cystatin", "eco_id": "ECO_0000259", "start_pos": 3, "end_pos": 90, "start_aa": "Leu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7EZ09-1", "uniprot_ac": "E7EZ09", "uniprot_id": "E7EZ09_DANRE", "mass": { "chemical_mass": 40303.0, "monoisotopic_mass": 40303.0 }, "refseq": { "ac": "XP_005155912", "name": "zinc finger matrin-type protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155912" }, "gene_names": [ { "name": "zmat3", "type": "recommended", "evidence": [ { "id": "E7EZ09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ09" } ] }, { "name": "zmat3", "type": "synonym", "evidence": [ { "id": "XP_005155912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155912" } ] } ], "protein_names": [ { "name": "Zinc finger matrin-type protein 3", "type": "recommended", "evidence": [ { "id": "E7EZ09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ09/entry#names_and_taxonomy" } ] }, { "name": "zinc finger matrin-type protein 3", "type": "synonym", "evidence": [ { "id": "XP_005155912", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155912" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005155912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155912" } ] }, { "annotation": "Acts as a bona fide target gene of p53/TP53. May play a role in the TP53-dependent growth regulatory pathway. May contribute to TP53-mediated apoptosis by regulation of TP53 expression and translocation to the nucleus and nucleolus.", "evidence": [ { "database": "UniProtKB", "id": "E7EZ09", "url": "https://www.uniprot.org/uniprotkb/E7EZ09#function" }, { "database": "UniProtKB", "id": "ARBA00054392", "url": "https://www.uniprot.org/uniprotkb/ARBA00054392#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZ09", "url": "https://www.uniprot.org/uniprotkb/E7EZ09" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "zmat3", "url": "https://www.uniprot.org/uniprotkb/E7EZ09", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-881", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-881", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000080021", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000080021", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "561535", "url": "https://www.ncbi.nlm.nih.gov/gene/561535", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003604", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003604", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052644", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052644", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561535", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561535", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YRGKNHA", "url": "https://omabrowser.org/oma/group/YRGKNHA/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EZ09", "url": "https://www.orthodb.org/?gene=E7EZ09", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR46786", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46786", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR46786:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR46786:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12874", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12874", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005155912", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155912", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EZ09", "url": "https://www.uniprot.org/uniprotkb/E7EZ09", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZ09-1", "url": "https://www.uniprot.org/uniprotkb/E7EZ09-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-881", "url": "https://zfin.org/ZDB-GENE-130530-881", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAMNVKNRDAFYSGADYCNIYSSQPVNYGDCSHYFPRITGPDPILKPPISLMCQQPPQPFQAMTPTQNLRPPPVMMPDPLPFPHCTPPIKPPPHLQLPPNPPLPPPPVISPKPPEEDAQAVAADQEATLEELCKPLYCKLCNVTLNSAQQAQAHYQGKNHSKKLRNFYAGSQQPPPITIPEVVEPVSQQPSATTPTDSANATANQPLTKGASRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQQNATSSDLSDTQRRPRKEGYEYRLMKNRRAQFNTAMPGPYYNPRPRQRIPRDLAMCVTPSGQFYCSMCNSGASEEAEFRLHLESKQHKSRVSEQRYRSEMENLGYT", "length": 361, "header": "tr|E7EZ09-1|E7EZ09_DANRE Isoform 1 of Zinc finger matrin-type protein 3 OS=Danio rerio OX=7955 GN=zmat3 PE=4 SV=1 CANONICAL=E7EZ09-1" }, "isoforms": [ { "isoform_ac": "E7EZ09-1", "url": "https://www.uniprot.org/uniprotkb/E7EZ09/entry#E7EZ09-1", "sequence": { "sequence": "MAMNVKNRDAFYSGADYCNIYSSQPVNYGDCSHYFPRITGPDPILKPPISLMCQQPPQPFQAMTPTQNLRPPPVMMPDPLPFPHCTPPIKPPPHLQLPPNPPLPPPPVISPKPPEEDAQAVAADQEATLEELCKPLYCKLCNVTLNSAQQAQAHYQGKNHSKKLRNFYAGSQQPPPITIPEVVEPVSQQPSATTPTDSANATANQPLTKGASRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQQNATSSDLSDTQRRPRKEGYEYRLMKNRRAQFNTAMPGPYYNPRPRQRIPRDLAMCVTPSGQFYCSMCNSGASEEAEFRLHLESKQHKSRVSEQRYRSEMENLGYT", "length": 361, "header": "tr|E7EZ09-1|E7EZ09_DANRE Isoform 1 of Zinc finger matrin-type protein 3 OS=Danio rerio OX=7955 GN=zmat3 PE=4 SV=1 CANONICAL=E7EZ09-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 313, "start_aa": "Thr", "end_pos": 313, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr313", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:561535", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561535", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A1D5PUH8-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "ZMAT3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MILLQQAGLLSHPEKPSSLPMSVATRPRATSPLSPPKSLGLGPSFYHAQDEELAKVVEQDPMLEELCKPLCCKLCNVTLNSAQQAQAHYQGKNHSKKLRNYYAANSCPAPTRMSNSVEPVPPQVVSLPAQMGSSKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQNNSFSDASELGKRRTRKEGNEYKMMQNRRNMYTVQNNTGPYFNPRSRQRIPRDLAMCVTPSGQFYCSMCNAGASEEMEFRQHLESKQHKSKVSEQRYRNEMENLGYVQ", "length": 289 }, "evidence": [ { "id": "E7EZ09", "url": "https://omabrowser.org/oma/group/E7EZ09/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A287BFA4-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "ZMAT3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MILLQHAGLPPPKRPSSSLPMSVAARSTGTFQLPPPKAFGQEASLSLAGEEELPKGGEQDSALEELCKPLYCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARMSNAVEPVATTAVPVPPQMGSFKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSNSFSESSEVGQRRTRKEGNEYKMMPNRRNMYAVQNNSAGPYFNPRSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRNEMENLGYV", "length": 289 }, "evidence": [ { "id": "E7EZ09", "url": "https://omabrowser.org/oma/group/E7EZ09/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "G3I1C4-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "Zmat3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MILLQQAGLPPPKRPSTSPPMSVAARSTRTLQLPPQKPFGQEASLPLAGEEELTKGEEPDSALEELCKPLFCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPTRMSTVAEPVATPLVPVPPQVGSCKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSNSFSDSAAEAGQRRTRKEGSEFKMVATRRNMHTVQNNSGPYFNARSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRSEMENLGYVQ", "length": 290 }, "evidence": [ { "id": "E7EZ09", "url": "https://omabrowser.org/oma/group/E7EZ09/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "O08781-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "Zmat3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MILLQQVWLPLPNRPSTSPPMSVAARSTGTLQLPPQKAFGQEASLPLAGEEDLAKRGEPDSALEELCKPLFCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARMSSVAEPVATPLVPVPPQVGSCKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSHSFSDSAEAGQRRTRKEGSEFKMVTTRRNMYTVQSNSGPYFNARSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRSEMENLGYVQ", "length": 289 }, "evidence": [ { "id": "HGNC:29983", "url": "https://alliancegenome.org/gene/HGNC:29983#orthology", "database": "AGR" }, { "id": "MGI:1195270", "url": "https://alliancegenome.org/gene/MGI:1195270#orthology", "database": "AGR" }, { "id": "E7EZ09", "url": "https://omabrowser.org/oma/group/E7EZ09/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O54836-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "Zmat3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MILLQQVWLPLPNRPSTSPPMSVAARSTRTLQLPPQKAFGQEASLPLAGEEDLAKRGEPDSALEELCKPLFCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARVSSVVAEPVATPLVPVPPQVGSCKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSHSFSDSAEAGQRRTRKEGSEFKMVATRRNMNPVQSNSGPYFNARSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRSEMENLGYVQ", "length": 290 }, "evidence": [ { "id": "HGNC:29983", "url": "https://alliancegenome.org/gene/HGNC:29983#orthology", "database": "AGR" }, { "id": "MGI:1195270", "url": "https://alliancegenome.org/gene/MGI:1195270#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-881", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-881#orthology", "database": "AGR" }, { "id": "E7EZ09", "url": "https://omabrowser.org/oma/group/E7EZ09/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q0IIC4-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "ZMAT3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MILLQHAGLPPPKRPSSSPPMSVAARSTGALQLPPQKPFGQEASLPLAGEEEPPKGGEQDTALEELCKPLYCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARMSNAVEAVAAPAVSVPPQMGSFKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSNSFSDSSEVGQRRTRKEGNEYKMMPNRRNMYAVQNNSAGPYFNPRSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEVEFRQHLESKQHKSKVSEQRYRNEMENLGYV", "length": 289 }, "evidence": [ { "id": "E7EZ09", "url": "https://omabrowser.org/oma/group/E7EZ09/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9HA38-1", "protein_name": "Zinc finger matrin-type protein 3", "gene_name": "ZMAT3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MILLQHAVLPPPKQPSPSPPMSVATRSTGTLQLPPQKPFGQEASLPLAGEEELSKGGEQDCALEELCKPLYCKLCNVTLNSAQQAQAHYQGKNHGKKLRNYYAANSCPPPARMSNVVEPAATPVVPVPPQMGSFKPGGRVILATENDYCKLCDASFSSPAVAQAHYQGKNHAKRLRLAEAQSNSFSESSELGQRRARKEGNEFKMMPNRRNMYTVQNNSAGPYFNPRSRQRIPRDLAMCVTPSGQFYCSMCNVGAGEEMEFRQHLESKQHKSKVSEQRYRNEMENLGYV", "length": 289 }, "evidence": [ { "id": "HGNC:29983", "url": "https://alliancegenome.org/gene/HGNC:29983#orthology", "database": "AGR" }, { "id": "MGI:1195270", "url": "https://alliancegenome.org/gene/MGI:1195270#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-881", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-881#orthology", "database": "AGR" }, { "id": "E7EZ09", "url": "https://omabrowser.org/oma/group/E7EZ09/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9VKS7-1", "protein_name": "Doublefault", "gene_name": "dbf", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MLSHAFNMHPQRRVPVIHEQIAKQCALNIVRVASAMPQPQPRCPSGHVVVLVELRRTDEQTVHRYQVNVPPTGWTNEDLEEEEKRFQQLVLPGTLDSMGLKLPLPERPPCPMHGRSIMEMGWSPNSNMGPPPMLMIQSSVHITNGQDGATDFATFREPVVTSESPDNLRAHFMASLYQQQPSPLSYSDIWVSDSPSTGLPRSEALSTTHFPQFYLGENAESMVANKIRPINGYPINGYPISGYPTVPRPAVKKPRHVAELCLDSNGEYVLNKQLHQPLISRQPDPIIPSVSSRDPHYFIQNQSHQLESAIKGLNGYTNVAQESEKPKNGYKYQPAAFADQRIVLQPKLGQGQGQAQGAVPGFIPNHLQSRVAMVEPRIRQESLIKPQNPDLALPSEAHPPVPQDLQSLFRWNYCALCNMVIRSTQSAIDHYSSRAHERRISSWLVRKCYANLTGRDADALGGAISQSEFYCKLCDLKLTSLSHAQQHFLGRRHRIAARHRIRPFSDGFYDREGNWVRTDIKYPMCELCDVIITSESQMAMHLAGARHRRRVQIAYAGESAGGMEMGIGLVPFDGSHMYRIRGNGSLAPIRPLGSQLLQGSAYPLSLTDPSAVFYCDACNITLNHLKSVNQHEQGRMHRRNMHRLPAQAVFFE", "length": 652 }, "evidence": [ { "id": "HGNC:29983", "url": "https://alliancegenome.org/gene/HGNC:29983#orthology", "database": "AGR" }, { "id": "MGI:1195270", "url": "https://alliancegenome.org/gene/MGI:1195270#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9W0R2-1", "protein_name": "Matrin-type domain-containing protein", "gene_name": "Dmel\\CG1231", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSCPGSLRGFHIPHLAPGETPKIRVDSACIESHPDAEISTSNRLVAPGKRTDKKDNGSIRTNMKRKAKCMEEDSLKANGDLALFPGRDESYPEELNRLIGPLNCQLCKVQMTSRKRARDHYESKAHDRHISAWLAKNYTEVGLEAPPVKRLAKQGPTGPNAFHCELCNLDLTSSMHARQHYLGRKHKRVEQGVAKPSGARHCDTSVGRYGIGSLFRKPESLTKDSPTDVLISENSVIKSDDNERTCHLCKIVVTSAAQMQAHLAGARHQKNWRTSRQDQNHSEAPIPETEKLDAAELALYRTPMGQYYCQPCNMMMNHESTLQQHFIGKKHLKRVKNLSQTEKNV", "length": 345 }, "evidence": [ { "id": "HGNC:29983", "url": "https://alliancegenome.org/gene/HGNC:29983#orthology", "database": "AGR" }, { "id": "MGI:1195270", "url": "https://alliancegenome.org/gene/MGI:1195270#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "RNA binding", "id": "GO:0003723", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003723", "evidence": [ { "database": "UniProtKB", "id": "E7EZ09", "url": "https://www.uniprot.org/uniprotkb/E7EZ09" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7EZ09", "url": "https://www.uniprot.org/uniprotkb/E7EZ09" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nucleolus", "id": "GO:0005730", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005730", "evidence": [ { "database": "UniProtKB", "id": "E7EZ09", "url": "https://www.uniprot.org/uniprotkb/E7EZ09" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "protein transport", "id": "GO:0015031", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015031", "evidence": [ { "database": "UniProtKB", "id": "E7EZ09", "url": "https://www.uniprot.org/uniprotkb/E7EZ09" } ], "pmid": "" }, { "name": "apoptotic process", "id": "GO:0006915", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006915", "evidence": [ { "database": "UniProtKB", "id": "E7EZ09", "url": "https://www.uniprot.org/uniprotkb/E7EZ09" } ], "pmid": "" }, { "name": "DNA damage response", "id": "GO:0006974", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006974", "evidence": [ { "database": "UniProtKB", "id": "E7EZ09", "url": "https://www.uniprot.org/uniprotkb/E7EZ09" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 142, "end_pos": 144, "annotation": "n_glycosylation_sequon" }, { "start_pos": 159, "end_pos": 161, "annotation": "n_glycosylation_sequon" }, { "start_pos": 200, "end_pos": 202, "annotation": "n_glycosylation_sequon" }, { "start_pos": 257, "end_pos": 259, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EZ09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ09" }, { "id": "SM00355", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00355" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C2H2-type", "eco_id": "ECO_0000259", "start_pos": 136, "end_pos": 160, "start_aa": "Leu", "end_aa": "His", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7EZ09", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ09" }, { "id": "SM00451", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00451" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "U1-type", "eco_id": "ECO_0000259", "start_pos": 133, "end_pos": 167, "start_aa": "Cys", "end_aa": "Phe", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 313 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 142, "end_pos": 144 }, { "start_pos": 159, "end_pos": 161 }, { "start_pos": 200, "end_pos": 202 }, { "start_pos": 257, "end_pos": 259 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EZ14-1", "uniprot_ac": "E7EZ14", "uniprot_id": "E7EZ14_DANRE", "mass": { "chemical_mass": 24419.0, "monoisotopic_mass": 24419.0 }, "refseq": { "ac": "XP_068070627", "name": "keratinocyte-associated protein 3 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070627" }, "gene_names": [ { "name": "krtcap3", "type": "recommended", "evidence": [ { "id": "E7EZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ14" } ] }, { "name": "krtcap3", "type": "synonym", "evidence": [ { "id": "XP_068070627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070627" } ] } ], "protein_names": [ { "name": "Keratinocyte-associated protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "E7EZ14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ14/entry#names_and_taxonomy" } ] }, { "name": "keratinocyte-associated protein 3 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_068070627", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070627" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068070627", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070627" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZ14", "url": "https://www.uniprot.org/uniprotkb/E7EZ14" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "krtcap3", "url": "https://www.uniprot.org/uniprotkb/E7EZ14", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-240410-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-240410-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100538219", "url": "https://www.ncbi.nlm.nih.gov/gene/100538219", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR020977", "url": "https://www.ebi.ac.uk/interpro/entry/IPR020977", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100538219", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100538219", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7EZ14", "url": "https://www.orthodb.org/?gene=E7EZ14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31258", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31258", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31258:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31258:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF12304", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12304", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_068070627", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068070627", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58HQL3", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQL3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58HQL3-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58HQL3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZ14", "url": "https://www.uniprot.org/uniprotkb/E7EZ14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZ14-1", "url": "https://www.uniprot.org/uniprotkb/E7EZ14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-240410-1", "url": "https://zfin.org/ZDB-GENE-240410-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MCDFDKQKGPGRLMKKGLTLIVIGHVNFILSAIVHGSVLRHVSKPSNEISTEYTVSNIISVSSGLLSIGSGIVAILVSRNIANWKLHIGLLVSSFLNALLTLACLLGLILAISLTISGDGSALMKGCNSTNMPVNARSPVIVNCPFDATRIYDTTLALWFTCGAFTAVEAGLSVWCFIVGLQLRGIGPCAQNYIREQLEEEAQASRSKMEEDHTTQGVRLIAHHSASP", "length": 228, "header": "tr|E7EZ14-1|E7EZ14_DANRE Isoform 1 of Keratinocyte-associated protein 3 isoform X1 OS=Danio rerio OX=7955 GN=krtcap3 PE=3 SV=1 CANONICAL=E7EZ14-1" }, "isoforms": [ { "isoform_ac": "A0AC58HQL3-1", "url": "https://www.uniprot.org/uniprotkb/E7EZ14/entry#A0AC58HQL3-1", "sequence": { "sequence": "MKKGLTLIVIGHVNFILSAIVHGSVLRHVSKPSNEISTEYTVSNIISVSSGLLSIGSGIVAILVSRNIANWKLHIGLLVSSFLNALLTLACLLGLILAISLTISGDGSALMKGCNSTNMPVNARSPVIVNCPFDATRIYDTTLALWFTCGAFTAVEAGLSVWCFIVGLQLRGIGPCAQNYIREQLEEEAQASRSKMEEDHTTQGVRLIAHHSASP", "length": 215, "header": "tr|A0AC58HQL3-1|A0AC58HQL3_DANRE Computationally mapped isoform of Keratinocyte-associated protein 3 isoform X2 OS=Danio rerio OX=7955 GN=krtcap3 PE=3 SV=1 CANONICAL=E7EZ14-1" }, "locus": {} }, { "isoform_ac": "E7EZ14-1", "url": "https://www.uniprot.org/uniprotkb/E7EZ14/entry#E7EZ14-1", "sequence": { "sequence": "MCDFDKQKGPGRLMKKGLTLIVIGHVNFILSAIVHGSVLRHVSKPSNEISTEYTVSNIISVSSGLLSIGSGIVAILVSRNIANWKLHIGLLVSSFLNALLTLACLLGLILAISLTISGDGSALMKGCNSTNMPVNARSPVIVNCPFDATRIYDTTLALWFTCGAFTAVEAGLSVWCFIVGLQLRGIGPCAQNYIREQLEEEAQASRSKMEEDHTTQGVRLIAHHSASP", "length": 228, "header": "tr|E7EZ14-1|E7EZ14_DANRE Isoform 1 of Keratinocyte-associated protein 3 isoform X1 OS=Danio rerio OX=7955 GN=krtcap3 PE=3 SV=1 CANONICAL=E7EZ14-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100538219", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100538219", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287B459-1", "protein_name": "Keratinocyte associated protein 3", "gene_name": "KRTCAP3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MKRCRLCTFDADRGPPRLMRVGLALILVGHVNLLLGAVLHGTVLRHVANPRGAVTPEYTTANIISVGSGLLSVSLGLVALLASRNLLRPQLHWALLALALVNLLLSAACSLGLLLAVSLTIANGGRRLIADCHPGLLDPLLPLDEGHGHADCPFDPTRIYDTALALWIPSLLMSAAEAALSGYCCVAALTLRGVGPCRRAGLQEQLEEMTELELPKCKRQENEQLLDQTHEIRTSQKSWV", "length": 240 }, "evidence": [ { "id": "E7EZ14", "url": "https://omabrowser.org/oma/group/E7EZ14/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0A3Q1LXT6-1", "protein_name": "Keratinocyte associated protein 3", "gene_name": "KRTCAP3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MRCRRLWAFGNFRPLRPCFPPRAHPGPALGPVADLGWPPAPQPAQRAPRLCLADAARGPRRLMRVGLALILVGHVNLLLGAVLHGTVLRHVANPRGAVTPEYTTANVISVGSGLLSVSLGLVALLASRNLFRPRLHWALLALALVNLLLSAACSLGLLLAVSLTVANGGRRLIADCHPGLLDPLVPLDQGSGHADCPFDPTKIYDTALALWIPSVFMSAAEAALSGYCCVAALTLRGVGPCRKDGLQEQTLDYITEELEFPKRKWQENVQLLDQTREIRTSQKSWV", "length": 286 }, "evidence": [ { "id": "E7EZ14", "url": "https://omabrowser.org/oma/group/E7EZ14/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0A8V0Y1F6-1", "protein_name": "Keratinocyte associated protein 3", "gene_name": "KRTCAP3", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAGGRAGRWWPGPLAEPQRLMRAGLGLIVLGHSNLVLGAIVHGSVLRHVAGAKGAVTPEYAVANVVSVVSGLLSITVGIVAILVSRNLTRAALHWALLSVSLLNCLLSTACSVGLALAIGLTIHSRGMRLVTGCSSPALPADARAAIATNDCPFNTTRIYDTALALWFPSMLLAATEAVLSGRCSLAALVMQGIGPCARRYSKDQVARPGTVKERQLLVGMAETCA", "length": 226 }, "evidence": [ { "id": "E7EZ14", "url": "https://omabrowser.org/oma/group/E7EZ14/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "Q497B3-1", "protein_name": "Keratinocyte-associated protein 3", "gene_name": "Krtcap3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRCCRVCAFDAARGPRRLMRVGLALILVGHVNLLVGAVLHGTVLRHVANPRGAVTPEYTTANVISVGSGLLSVTVGLVALLASRNLLLPRLHWALLTLALVNLLLSAACSMGLLLAVSLTIANGGRRLIADCHPGLMDHSIPLDQGPGHTDCPFDPTRIYDTALALWIPSLFMSAAEAVLSGYCCVAALTLRGIGPFRKEGLQGQLEELTELEPLECKRQENIQLLHHHQDFQALQKTWV", "length": 240 }, "evidence": [ { "id": "E7EZ14", "url": "https://omabrowser.org/oma/group/E7EZ14/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q53RY4-1", "protein_name": "Keratinocyte-associated protein 3", "gene_name": "KRTCAP3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MRRCSLCAFDAARGPRRLMRVGLALILVGHVNLLLGAVLHGTVLRHVANPRGAVTPEYTVANVISVGSGLLSVSVGLVALLASRNLLRPPLHWVLLALALVNLLLSVACSLGLLLAVSLTVANGGRRLIADCHPGLLDPLVPLDEGPGHTDCPFDPTRIYDTALALWIPSLLMSAGEAALSGYCCVAALTLRGVGPCRKDGLQGQLEEMTELESPKCKRQENEQLLDQNQEIRASQRSWV", "length": 240 }, "evidence": [ { "id": "E7EZ14", "url": "https://omabrowser.org/oma/group/E7EZ14/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K177-1", "protein_name": "Keratinocyte-associated protein 3", "gene_name": "Krtcap3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MRCCGVCAFDAARGPRRLMRVGLALILVGHVNLLVGAVLHGTVLRHVANPRGAVTPEYTTANVISVGSGLLSVSVGLVALLASRNLLRPRLHWALLTLALVNLLLSAACSMGLLLAVSLTVANGGRRLIADCHPGLMDPSIPLDQGPGHTDCSFDPTRIYDTALALWIPSLFMSAAEAALSGYCCVAALTLRGIGPCRKEGLQEQLQELTELELPECKRQENVQLLHGRQDFQALQKTWV", "length": 240 }, "evidence": [ { "id": "E7EZ14", "url": "https://omabrowser.org/oma/group/E7EZ14/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7EZ14", "url": "https://www.uniprot.org/uniprotkb/E7EZ14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 128, "end_pos": 130 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EZ29-1", "uniprot_ac": "E7EZ29", "uniprot_id": "E7EZ29_DANRE", "mass": { "chemical_mass": 60544.0, "monoisotopic_mass": 60544.0 }, "refseq": { "ac": "XP_693575", "name": "general transcription factor 3C polypeptide 5", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693575" }, "gene_names": [ { "name": "gtf3c5", "type": "recommended", "evidence": [ { "id": "E7EZ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ29" } ] }, { "name": "gtf3c5", "type": "synonym", "evidence": [ { "id": "XP_693575", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693575" } ] } ], "protein_names": [ { "name": "General transcription factor 3C polypeptide 5", "type": "synonym", "evidence": [ { "id": "E7EZ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ29/entry#names_and_taxonomy" } ] }, { "name": "general transcription factor 3C polypeptide 5", "type": "synonym", "evidence": [ { "id": "XP_693575", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693575" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133196) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_693575.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_693575", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693575" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZ29", "url": "https://www.uniprot.org/uniprotkb/E7EZ29" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "gtf3c5", "url": "https://www.uniprot.org/uniprotkb/E7EZ29", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060810-66", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-66", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000067979", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000067979", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "565198", "url": "https://www.ncbi.nlm.nih.gov/gene/565198", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019136", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019136", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040454", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040454", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR041499", "url": "https://www.ebi.ac.uk/interpro/entry/IPR041499", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:565198", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565198", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PPEYFVR", "url": "https://omabrowser.org/oma/group/PPEYFVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EZ29", "url": "https://www.orthodb.org/?gene=E7EZ29", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR13230", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13230", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR13230:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR13230:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF09734", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09734", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF17682", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17682", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-76061", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-76061", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "R-DRE-76066", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-76066", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_693575", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_693575", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EZ29", "url": "https://www.uniprot.org/uniprotkb/E7EZ29", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZ29-1", "url": "https://www.uniprot.org/uniprotkb/E7EZ29-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060810-66", "url": "https://zfin.org/ZDB-GENE-060810-66", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MHKRQTKMDSVITSEAVSSDTEARNTGESRDEAVVLGNTATLALSDTNLVCVEYPAVVNNVNRMLDSIGGEQGVSKTYADSTKRIELRFRPGDPFCHPAYGNRYSSTNLLLRVRRRTRKGNNAETQISMEIVGLIGTTYKFQGMADFQYLASHNNPEGNQVSLYDKIILRKPEKKEFYDNPVPLFIPPPIFSRLDMPVDYFYRPDVMHNKDTAFQSALMKDHIIAPNRARRPNNAIFVNFDDKTIPSEPLEAAVTTWRKLCVHPNDLKAEKKIKQLFEKRPIWSRNAVKANIDIHPEKMKHLLPFVAYYALTGPWRSLWVRFGYDPRKIPGAKIYQVLDFRIRYGMKHGFGVNDMPVKSKRSAYHYSRPTTFNRAVPLPASVTDIPQESTSSSGPVTAKYMLKESIYIFREGMLPPYRQMFYQLCDLDVEKIQNLIHKNDGKEEVCDERDGWCVPHTADELRNIISGMIQQYVKANRPGPSTQKPVKRRAKDVGSGEEDDEDEDDDDDEEYKPSDGSDNEMETEIADYM", "length": 529, "header": "tr|E7EZ29-1|E7EZ29_DANRE Isoform 1 of General transcription factor 3C polypeptide 5 OS=Danio rerio OX=7955 GN=gtf3c5 PE=1 SV=1 CANONICAL=E7EZ29-1" }, "isoforms": [ { "isoform_ac": "E7EZ29-1", "url": "https://www.uniprot.org/uniprotkb/E7EZ29/entry#E7EZ29-1", "sequence": { "sequence": "MHKRQTKMDSVITSEAVSSDTEARNTGESRDEAVVLGNTATLALSDTNLVCVEYPAVVNNVNRMLDSIGGEQGVSKTYADSTKRIELRFRPGDPFCHPAYGNRYSSTNLLLRVRRRTRKGNNAETQISMEIVGLIGTTYKFQGMADFQYLASHNNPEGNQVSLYDKIILRKPEKKEFYDNPVPLFIPPPIFSRLDMPVDYFYRPDVMHNKDTAFQSALMKDHIIAPNRARRPNNAIFVNFDDKTIPSEPLEAAVTTWRKLCVHPNDLKAEKKIKQLFEKRPIWSRNAVKANIDIHPEKMKHLLPFVAYYALTGPWRSLWVRFGYDPRKIPGAKIYQVLDFRIRYGMKHGFGVNDMPVKSKRSAYHYSRPTTFNRAVPLPASVTDIPQESTSSSGPVTAKYMLKESIYIFREGMLPPYRQMFYQLCDLDVEKIQNLIHKNDGKEEVCDERDGWCVPHTADELRNIISGMIQQYVKANRPGPSTQKPVKRRAKDVGSGEEDDEDEDDDDDEEYKPSDGSDNEMETEIADYM", "length": 529, "header": "tr|E7EZ29-1|E7EZ29_DANRE Isoform 1 of General transcription factor 3C polypeptide 5 OS=Danio rerio OX=7955 GN=gtf3c5 PE=1 SV=1 CANONICAL=E7EZ29-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:565198", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:565198", "resource": "KEGG Pathway" }, { "id": "R-DRE-76061", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-76061", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 1 Promoter" }, { "id": "R-DRE-76066", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-76066", "resource": "Reactome", "description": "RNA Polymerase III Transcription Initiation From Type 2 Promoter" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8V1AFN2-1", "protein_name": "General transcription factor 3C polypeptide 5", "gene_name": "GTF3C5", "tax_id": 9031, "organism": "Gallus gallus", "sequence": { "sequence": "MAADGPRTERGSGVLELPSTPRLVCVEYPGLVRDVSAMLRTLGGEEGVSRIYADPGKRLELYFRPKDPYCHPVCANRFPASAMLLRVKRRSRRKRLGEQDVQFEMEIMGIVTTVYKFQGMSDFQYLAMHSGPDGKQTSMYDKVLMLKPEKEEFFNRELPLYIPPPIFSRLDTPVDYYYRPDVQHREGYNNPQVSAENLIGLSRARRPNNAIFVNFDDEVPTKPLDAAAQAWKKVCTNPVDRKVEEELRKLFEVRPVWSRNAVKANISVHPDKLKLLLPCLAYYMITGPWRSLWVRFGYDPRKHPEAKIYQVLDFRIRCGMKYGYTPNDMPVKAKRSTYNYSLPITVKKPVSHTVSVHDLKQGLGTPGASGAKKPASSRYKLKESVYIFREGALPPYRQMFYQLCDLNVESLQKIIHRNDGTESECTERDGWCLPKTSDDLRDSMSLMIKQIIRSTRPALFSSTTSSEDGKEQLAYESGEDEDDEEEEEEEFKPSDGSENEMETEILDYV", "length": 509 }, "evidence": [ { "id": "E7EZ29", "url": "https://omabrowser.org/oma/group/E7EZ29/", "database": "OMA" } ], "glygen_name": "Chicken", "common_name": "Chicken" }, { "uniprot_canonical_ac": "A0A9J7JMF5-1", "protein_name": "General transcription factor 3C polypeptide 5 isoform X5", "gene_name": "Gtf3c5", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MAAVEPDAEPKAAIPVDLRRERRLVCVEYPGVVRNEDKMLQTLGGEEGVSRVRSWENSGTAGKEPGERAVSLIYTDPTKRLELYFRPKDPYCHPVCANRFSTSSMLLRIRKRTRRQRGALGAETHPQVTFDLEILGIISTIYKFQGMSDFQYLAVHTEAGGKHVSMYDRVLMRKPEKEEFFHQELPLYIPPPIFSRLDTPVDYFYRPETQHREGYHNPSISGENLIGLSRARRPHNAIFVNFEDPEVPLQPLEAAVTTWKKACTNPIDQKVEEELRKLFDVRPIWSRNAVKSNVSVHPDKLKILLPYMAYYMITGPWRSLWIRFGYDPRKHPDAKIYQVLDFRIRCGMKYGYGSRDMPVKAKRSTYNYSLPITVKKTSNQLVTMHDLKQGLGPSGTDGPRKLTYNKYKLKDSVYIFREGALPPYRQMFYQLCDLNVEELQKIVHRNDGTESVCTERDGWCLPKTTDHLRDTMSLMILQTIRSERPALFSDTGKTDRGKGQLMFESGEEGEEEEEEEDEEDFKPSDGSENEMETEILDYV", "length": 539 }, "evidence": [ { "id": "E7EZ29", "url": "https://omabrowser.org/oma/group/E7EZ29/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "P32367-1", "protein_name": "Transcription factor tau 95 kDa subunit", "gene_name": "TFC1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MPVEEPLATLSSIPDSSADQAPPLIADEFTLDLPRIPSLELPLNVSTKHSSIQKAIKMCGGIEKVKEAFKEHGPIESQHGLQLYLNDDTDSDGSKSYFNEHPVIGKRVPFRDESVILKVTMPKGTLSKNNNSVKDSIKSLKDSNKLRVTPVSIVDNTIKFREMSDFQIKLDNVPSAREFKSSFGSLEWNNFKSFVNSVPDNDSQPQENIGNLILDRSVKIPSTDFQLPPPPKLSMVGFPLLYKYKANPFAKKKKNGVTEVKGTYIKNYQLFVHDLSDKTVIPSQAHEQVLYDFEVAKKTKVYPGTKSDSKFYESLEECLKILRELFARRPIWVKRHLDGIVPKKIHHTMKIALALISYRFTMGPWRNTYIKFGIDPRSSVEYAQYQTEYFKIERKLLSSPIVKKNVPKPPPLVFESDTPGGIDSRFKFDGKRIPWYLMLQIDLLIGEPNIAEVFHNVEYLDKANELTGWFKELDLVKIRRIVKYELGCMVQGNYEYNKYKLKYFKTMLFVKESMVPENKNSEEGMGVNTNKDADGDINMDAGSQMSSNAIEEDKGIAAGDDFDDNGAITEEPDDAALENEEMDTDQNLKVPASIDDDVDDVDADEEEQESFDVKTASFQDIINKIAKLDPKTAETMKSELKGFVDEVDL", "length": 649 }, "evidence": [ { "id": "MGI:1917489", "url": "https://alliancegenome.org/gene/MGI:1917489#orthology", "database": "AGR" }, { "id": "HGNC:4668", "url": "https://alliancegenome.org/gene/HGNC:4668#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q8R2T8-1", "protein_name": "General transcription factor 3C polypeptide 5", "gene_name": "Gtf3c5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAEPDADPKAAIPVDLRRERRLVCVEYPGVVRNEAKMLQTLGGEESVSRIYTDPTKRLELYFRPKDPYCHPVCANRFSTSSLLLRIRKRTRRRRGVLGDEAHPQVTFNLEIIGIISTIYKFQGMSDFQYLAVHTEAGGKHVSMYDRVLMRKPEKEEFFHQELPLYIPPPIFSRLDTPVDYFYRPETQHREGYHNPTISGENLIGLSRARRPHNAIFVNFEDTEVPEQPLEAAVQTWKKACTNPIDQKVEEELRKLFDIRPVWSRNAVKSNVSVHPDKLKILLPYMAYYMITGPWRSLWIRFGYDPRKHPDAKIYQVLDFRIRCGMKYGYGSRDMPVKAKRSTYNYSLPITVKKTSNQPGTMHDLKQGLGPSGTDGPRKLTYNKYKLKDSVYIFREGALPPYRQMFYQLCDLNVEELQKIVHRNDGTETVCTERDGWCLPKTTDHLRDTMSLMILQTIRSERPALFSNTGKADRGKEQLMFESGEEEEEEEEEEEEEEEDFKPSDGSENEMETEILDYV", "length": 520 }, "evidence": [ { "id": "MGI:1917489", "url": "https://alliancegenome.org/gene/MGI:1917489#orthology", "database": "AGR" }, { "id": "HGNC:4668", "url": "https://alliancegenome.org/gene/HGNC:4668#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060810-66", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-66#orthology", "database": "AGR" }, { "id": "E7EZ29", "url": "https://omabrowser.org/oma/group/E7EZ29/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VIZ2-1", "protein_name": "Lethal (2) 37Cd", "gene_name": "l(2)37Cd", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MSRQLSFNPQKEYELIEYPGRVVNPDRMIATLGGIINVSKVLGDEVKRLALHFHPENPYNKPTFGDCTDKTGVLLSITVRRHKKDKQRPPEYFVRVLGHCSRSFTFETLCDFQYLPLWSTPKSDNANAAQELTYALDQLKPKNTTDLDYFKRRHSQLLALPELFTHVDTVYAGTYRIDPSEDGQHEVLGVQSKSSYDNQGVVSFNMVDSFPTQADSQNLKRLKVKYVSDEQLALVKKLFDDCPIWTRIALQYESGLTNDKLKCITPSLAFYFSNGPWRTLYVRFGYDPRKDFNSRYYQTFDFRLRFSTGLSEFVYAKKFVKQRRAANAPFAPIEDRVSDLVQDIDYPYFDEHKLPRSRQCMLRYCDVRMTRIQEMLEKIPTPLTGAVCNERTGWLPPGFDAQVRQIVCASISELLRNHYRKENLTAEVEAVTQADEEDEDEAEDEETQEEDMELDETQAMGNSEQFVDNDIEQLFDNITS", "length": 480 }, "evidence": [ { "id": "MGI:1917489", "url": "https://alliancegenome.org/gene/MGI:1917489#orthology", "database": "AGR" }, { "id": "HGNC:4668", "url": "https://alliancegenome.org/gene/HGNC:4668#orthology", "database": "AGR" }, { "id": "E7EZ29", "url": "https://omabrowser.org/oma/group/E7EZ29/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y5Q8-1", "protein_name": "General transcription factor 3C polypeptide 5", "gene_name": "GTF3C5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAEAADLGLGAAVPVELRRERRMVCVEYPGVVRDVAKMLPTLGGEEGVSRIYADPTKRLELYFRPKDPYCHPVCANRFSTSSLLLRIRKRTRRQKGVLGTEAHSEVTFDMEILGIISTIYKFQGMSDFQYLAVHTEAGGKHTSMYDKVLMLRPEKEAFFHQELPLYIPPPIFSRLDAPVDYFYRPETQHREGYNNPPISGENLIGLSRARRPHNAIFVNFEDEEVPKQPLEAAAQTWRRVCTNPVDRKVEEELRKLFDIRPIWSRNAVKANISVHPDKLKVLLPFIAYYMITGPWRSLWIRFGYDPRKNPDAKIYQVLDFRIRCGMKHGYAPSDLPVKAKRSTYNYSLPITVKKTSSQLVTMHDLKQGLGPSGTSGARKPASSKYKLKDSVYIFREGALPPYRQMFYQLCDLNVEELQKIIHRNDGAENSCTERDGWCLPKTSDELRDTMSLMIRQTIRSKRPALFSSSAKADGGKEQLTYESGEDEEDEEEEEEEEEDFKPSDGSENEMETEILDYV", "length": 519 }, "evidence": [ { "id": "MGI:1917489", "url": "https://alliancegenome.org/gene/MGI:1917489#orthology", "database": "AGR" }, { "id": "HGNC:4668", "url": "https://alliancegenome.org/gene/HGNC:4668#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060810-66", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060810-66#orthology", "database": "AGR" }, { "id": "E7EZ29", "url": "https://omabrowser.org/oma/group/E7EZ29/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 2, "go_terms": [ { "name": "transcription factor TFIIIC complex", "id": "GO:0000127", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000127", "evidence": [ { "database": "UniProtKB", "id": "E7EZ29", "url": "https://www.uniprot.org/uniprotkb/E7EZ29" } ], "pmid": "" }, { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7EZ29", "url": "https://www.uniprot.org/uniprotkb/E7EZ29" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "5S class rRNA transcription by RNA polymerase III", "id": "GO:0042791", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042791", "evidence": [ { "database": "UniProtKB", "id": "E7EZ29", "url": "https://www.uniprot.org/uniprotkb/E7EZ29" } ], "pmid": "" }, { "name": "transcription initiation at RNA polymerase III promoter", "id": "GO:0006384", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006384", "evidence": [ { "database": "UniProtKB", "id": "E7EZ29", "url": "https://www.uniprot.org/uniprotkb/E7EZ29" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 2, "go_terms": [ { "name": "DNA binding", "id": "GO:0003677", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003677", "evidence": [ { "database": "UniProtKB", "id": "E7EZ29", "url": "https://www.uniprot.org/uniprotkb/E7EZ29" } ], "pmid": "" }, { "name": "RNA polymerase III general transcription initiation factor activity", "id": "GO:0000995", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0000995", "evidence": [ { "database": "UniProtKB", "id": "E7EZ29", "url": "https://www.uniprot.org/uniprotkb/E7EZ29" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EZ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ29" }, { "id": "PF09734", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF09734" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transcription factor IIIC subunit 5 HTH", "eco_id": "ECO_0000259", "start_pos": 185, "end_pos": 341, "start_aa": "Phe", "end_aa": "Arg", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7EZ29", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ29" }, { "id": "PF17682", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF17682" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Transcription factor IIIC subunit Tfc1/Sfc1 triple barrel", "eco_id": "ECO_0000259", "start_pos": 50, "end_pos": 150, "start_aa": "Val", "end_aa": "Leu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EZ34-1", "uniprot_ac": "E7EZ34", "uniprot_id": "E7EZ34_DANRE", "mass": { "chemical_mass": 31491.0, "monoisotopic_mass": 31491.0 }, "refseq": { "ac": "NP_001314777", "name": "myb/SANT-like DNA-binding domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314777" }, "gene_names": [ { "name": "msantd1", "type": "recommended", "evidence": [ { "id": "E7EZ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ34" } ] }, { "name": "msantd1", "type": "synonym", "evidence": [ { "id": "NP_001314777", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314777" } ] } ], "protein_names": [ { "name": "Myb/SANT-like DNA-binding domain-containing protein 1", "type": "recommended", "evidence": [ { "id": "E7EZ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ34/entry#names_and_taxonomy" } ] }, { "name": "myb/SANT-like DNA-binding domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "NP_001314777", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314777" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQQ01062575.1, GDQH01033347.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA4476746, SAMEA4476789 [ECO:0006172] ##Evidence-Data-END## PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from JBMGRA010000007.1. On Jun 7, 2025 this sequence version replaced NP_001314777.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001314777", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314777" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZ34", "url": "https://www.uniprot.org/uniprotkb/E7EZ34" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "msantd1", "url": "https://www.uniprot.org/uniprotkb/E7EZ34", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-121227-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121227-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000078801", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000078801", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "798497", "url": "https://www.ncbi.nlm.nih.gov/gene/798497", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR026095", "url": "https://www.ebi.ac.uk/interpro/entry/IPR026095", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR044822", "url": "https://www.ebi.ac.uk/interpro/entry/IPR044822", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:798497", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798497", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FQFRRLK", "url": "https://omabrowser.org/oma/group/FQFRRLK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EZ34", "url": "https://www.orthodb.org/?gene=E7EZ34", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22666", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22666", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22666:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22666:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF13837", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13837", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001314777", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314777", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58G0R4", "url": "https://www.uniprot.org/uniprotkb/A0AC58G0R4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58G0R4-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58G0R4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZ34", "url": "https://www.uniprot.org/uniprotkb/E7EZ34", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZ34-1", "url": "https://www.uniprot.org/uniprotkb/E7EZ34-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-121227-1", "url": "https://zfin.org/ZDB-GENE-121227-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MASEDLCFSYTVPGSNEKHRRARNWTDSEMKALVYIWEEYVTELKKAKRNAKIYETMAKQLYELTGEQRHREEIKMKITNMTFQFRKLKYTANGGSSTPDWPYYKSIERILSKVPDHGHMSPPNLSSSGPSTSQHDPAVPQSAPPSGFLPEYTGSSEERDMNDEDDGLTDNSASSFETRSQPHKRRRLSHVSLRRKKLRVLDAMLKEQRRISHAVEEACHEVRRVMHQQNFLQVQSLQLQERMMNLLEKMIPAQSAPSWPNPASAKGLGTPTPE", "length": 274, "header": "tr|E7EZ34-1|E7EZ34_DANRE Isoform 1 of Myb/SANT-like DNA-binding domain-containing protein 1 OS=Danio rerio OX=7955 GN=msantd1 PE=1 SV=1 CANONICAL=E7EZ34-1" }, "isoforms": [ { "isoform_ac": "A0AC58G0R4-1", "url": "https://www.uniprot.org/uniprotkb/E7EZ34/entry#A0AC58G0R4-1", "sequence": { "sequence": "MNRQLIQLMFYAADALPASNLAHSIHLSLDCGTNWSTRRKFTRTRGRTCKLHTEMPTDPAGAQTFLLKLKYTANGGSSTPDWPYYKSIERILSKVPDHGHMSPPNLSSSGPSTSQHDPAVPQSAPPSGFLPEYTGSSEERDMNDEEDGLTDNSASSFETRSQPHKRRRLSHVSLRRKKLRVLDAMLKEQRRISHAVEEACHEVRRVMHQQNFLQVQSLQLQERMMNLLEKMIPAQSAPSWPNPASAKGLGTPTPE", "length": 255, "header": "tr|A0AC58G0R4-1|A0AC58G0R4_DANRE Computationally mapped isoform of Myb/SANT-like DNA-binding domain-containing protein 1 isoform X1 OS=Danio rerio OX=7955 GN=msantd1 PE=1 SV=1 CANONICAL=E7EZ34-1" }, "locus": {} }, { "isoform_ac": "E7EZ34-1", "url": "https://www.uniprot.org/uniprotkb/E7EZ34/entry#E7EZ34-1", "sequence": { "sequence": "MASEDLCFSYTVPGSNEKHRRARNWTDSEMKALVYIWEEYVTELKKAKRNAKIYETMAKQLYELTGEQRHREEIKMKITNMTFQFRKLKYTANGGSSTPDWPYYKSIERILSKVPDHGHMSPPNLSSSGPSTSQHDPAVPQSAPPSGFLPEYTGSSEERDMNDEDDGLTDNSASSFETRSQPHKRRRLSHVSLRRKKLRVLDAMLKEQRRISHAVEEACHEVRRVMHQQNFLQVQSLQLQERMMNLLEKMIPAQSAPSWPNPASAKGLGTPTPE", "length": 274, "header": "tr|E7EZ34-1|E7EZ34_DANRE Isoform 1 of Myb/SANT-like DNA-binding domain-containing protein 1 OS=Danio rerio OX=7955 GN=msantd1 PE=1 SV=1 CANONICAL=E7EZ34-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7EZ34", "url": "https://www.uniprot.org/uniprotkb/E7EZ34" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "E7EZ34", "url": "https://www.uniprot.org/uniprotkb/E7EZ34" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] } ], "pathway": [ { "id": "dre:798497", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798497", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AKQ1-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 1", "gene_name": "Msantd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQLCQGASSMAAAEVPGYLVSPQTEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMASKLFEMTGERRLGEEIKIKITNMTFQYRKLKCMTDSESVPPDWPYYLAIDRILAKVPESCEGKLPDGQQPGPSTSQTEASLSPSAKSTPLYLPYTQCSYEGRFEDDRSDSSSSLLSLKFRSEERPVKKRKMRSCHLQKKKLRLLEAMLEEQRRLSRAMEETCREVRRVLDQQNILQVQSLQLQERMMSLLEKIIAKSNV", "length": 265 }, "evidence": [ { "id": "HGNC:33741", "url": "https://alliancegenome.org/gene/HGNC:33741#orthology", "database": "AGR" }, { "id": "MGI:2684990", "url": "https://alliancegenome.org/gene/MGI:2684990#orthology", "database": "AGR" }, { "id": "E7EZ34", "url": "https://omabrowser.org/oma/group/E7EZ34/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "G3GWA9-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 1", "gene_name": "Msantd1", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MVRWPGLRPCLSAILNPAGASSMAAAEVPGYLVSPQTEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMASKLFEMTGERRLGEEIKIKITNMTFQYRKLKCMTDSESVPPDWPYYLAIDRILAKVPESCEGKLPDGQQPGPSTSQTEASLSPSAKSTPLYLPYTQCSYEGRFEDDRSDSSSSLLSLKFRSEERPVKKRKVRSCHLQKKKLRLLEAMLEEQRRLSRAMEETCREVRRVLDQQNILQVQSLQLQERMMSLLEKIIAKSNV", "length": 278 }, "evidence": [ { "id": "E7EZ34", "url": "https://omabrowser.org/oma/group/E7EZ34/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q6ZTZ1-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 1", "gene_name": "MSANTD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MVRGAGPGPSLSALSHPTGASGMAAAEGPGYLVSPQAEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMASKLFEMTGERRLGEEIKIKITNMTFQYRKLKCMTDSESAPPDWPYYLAIDGILAKVPESCDGKLPDSQPPGPSTSQTEASLSPPAKSTPLYFPYNQCSYEGRFEDDRSDSSSSLLSLKFRSEERPVKKRKVQSCHLQKKQLRLLEAMVEEQRRLSRAVEETCREVRRVLDQQHILQVQSLQLQERMMSLLERIITKSSV", "length": 278 }, "evidence": [ { "id": "HGNC:33741", "url": "https://alliancegenome.org/gene/HGNC:33741#orthology", "database": "AGR" }, { "id": "MGI:2684990", "url": "https://alliancegenome.org/gene/MGI:2684990#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121227-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121227-1#orthology", "database": "AGR" }, { "id": "E7EZ34", "url": "https://omabrowser.org/oma/group/E7EZ34/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BIL2-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein 1", "gene_name": "Msantd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MVRWPGLRPCLSAILNPAGASNMAAAEVPGYLVSPQTEKHRRARNWTDAEMRGLMLVWEEFFDELKQTKRNAKVYEKMASKLFEMTGERRLGEEIKIKITNMTFQYRKLKCMTDSESIPPDWPYYLAIDRILAKVPESCEGKLPDGQQPGPSTSQTEASLSPSAKSTPLYLPYTQCSYEGHFEDDRSDSSSSLLSLKFRSEERPVKKRKMRSCHLQKKKLRLLEAMLEEQRRLSRAMEETCREVRRVLDQQNILQVQSLQLQERMMSLLEKIIAKSNV", "length": 278 }, "evidence": [ { "id": "HGNC:33741", "url": "https://alliancegenome.org/gene/HGNC:33741#orthology", "database": "AGR" }, { "id": "MGI:2684990", "url": "https://alliancegenome.org/gene/MGI:2684990#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121227-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121227-1#orthology", "database": "AGR" }, { "id": "E7EZ34", "url": "https://omabrowser.org/oma/group/E7EZ34/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9I7H8-1", "protein_name": "Myb/SANT-like DNA-binding domain-containing protein", "gene_name": "CG5995", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPYEKFNKKRRQWEDSGVLELIKLWKVCAYELRTIKRNGHLYVAMAKQLTSLGVPVTALEVHFKVNNLTQRYRQEQKTFETTGIISTWKFYSQVDDVFKSLAAHTGYKDKRMTSASNTSSLPSTSESPVWKNPMSQQEFNSNNTEGFYKTEYGMHRHFMDHSQPPPNAGSVDNFMASSAAVAAVAAAASARLADNNMDQQMNTAAGGSGGSGGGGGNTNGGVANYQKIKKSHEDYDKFVDIVKNIVDTHKSTPDKVDTFGDFIKSYMKRWPERLQDEAINHITNYVIVKNMEHSMVSSHNPEGVNNRQ", "length": 308 }, "evidence": [ { "id": "HGNC:33741", "url": "https://alliancegenome.org/gene/HGNC:33741#orthology", "database": "AGR" }, { "id": "MGI:2684990", "url": "https://alliancegenome.org/gene/MGI:2684990#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "nuclear body", "id": "GO:0016604", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016604", "evidence": [ { "database": "UniProtKB", "id": "E7EZ34", "url": "https://www.uniprot.org/uniprotkb/E7EZ34" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "positive regulation of DNA-templated transcription", "id": "GO:0045893", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045893", "evidence": [ { "database": "UniProtKB", "id": "E7EZ34", "url": "https://www.uniprot.org/uniprotkb/E7EZ34" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 124, "end_pos": 126, "annotation": "n_glycosylation_sequon" }, { "start_pos": 24, "end_pos": 26, "annotation": "n_glycosylation_sequon" }, { "start_pos": 80, "end_pos": 82, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EZ34", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZ34" }, { "id": "PF13837", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13837" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Myb/SANT-like DNA-binding", "eco_id": "ECO_0000259", "start_pos": 23, "end_pos": 110, "start_aa": "Arg", "end_aa": "Ile", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 124, "end_pos": 126 }, { "start_pos": 24, "end_pos": 26 }, { "start_pos": 80, "end_pos": 82 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E9QC14-1", "uniprot_ac": "E9QC14", "uniprot_id": "E9QC14_DANRE", "mass": { "chemical_mass": 30580.0, "monoisotopic_mass": 30580.0 }, "refseq": { "ac": "NP_001313501", "name": "uncharacterized protein LOC563797 isoform 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313501" }, "gene_names": [ { "name": "si:dkey-26c10.5", "type": "recommended", "evidence": [ { "id": "E9QC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QC14" } ] }, { "name": "si:dkey-26c10.5", "type": "synonym", "evidence": [ { "id": "NP_001313501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313501" } ] }, { "name": "wu:fq38b10", "type": "synonym", "evidence": [ { "id": "NP_001313501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313501" }, { "id": "E9QC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QC14" } ] } ], "protein_names": [ { "name": "Uncharacterized protein LOC563797 isoform 1", "type": "synonym", "evidence": [ { "id": "E9QC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QC14/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein LOC563797 isoform 1", "type": "synonym", "evidence": [ { "id": "NP_001313501", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313501" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH437543.1, GFIL01037383.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA708836, SAMN01765705 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH437543.1, EH598364.1 and JBMGRA010000016.1. On May 21, 2016 this sequence version replaced XP_001335195.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001313501", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313501" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E9QC14", "url": "https://www.uniprot.org/uniprotkb/E9QC14" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:dkey-26c10.5", "url": "https://www.uniprot.org/uniprotkb/E9QC14", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060607-13", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060607-13", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000088023", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000088023", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "563797", "url": "https://www.ncbi.nlm.nih.gov/gene/563797", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050828", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050828", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:563797", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563797", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QQCADGW", "url": "https://omabrowser.org/oma/group/QQCADGW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EZ52", "url": "https://www.orthodb.org/?gene=E7EZ52", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "E9QC14", "url": "https://www.orthodb.org/?gene=E9QC14", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR45710", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45710", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR45710:SF28", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR45710:SF28", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001313501", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001313501", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EZ52", "url": "https://www.uniprot.org/uniprotkb/E7EZ52", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZ52-1", "url": "https://www.uniprot.org/uniprotkb/E7EZ52-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QC14", "url": "https://www.uniprot.org/uniprotkb/E9QC14", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E9QC14-1", "url": "https://www.uniprot.org/uniprotkb/E9QC14-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060607-13", "url": "https://zfin.org/ZDB-GENE-060607-13", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MESQQVVEVELEEIALVEEHNERENEDEQETEADTEKETADEGNVYSSLTDPSEYVYGVPSSTRSYTVNKDSSDIYRRVRLYRVVSLVLLVICVLLLIVVLVLFIKLTGMHSCQLTETTLEQECSLKKCQEVYQQPFERALGLCRDCGSGWLRFENTCYFLSETRLTWQKSREECRRKGGDLAVITNERVQMFLSKRAIVNYWIGLSHVGTNQWMWINNTVLTVRYWGDSSSSGECGIMVGEKSAERSWQPASCRLNLQYICQKM", "length": 265, "header": "tr|E9QC14-1|E9QC14_DANRE Isoform 1 of Uncharacterized protein LOC563797 isoform 1 OS=Danio rerio OX=7955 GN=si:dkey-26c10.5 PE=4 SV=1 CANONICAL=E9QC14-1" }, "isoforms": [ { "isoform_ac": "E7EZ52-1", "url": "https://www.uniprot.org/uniprotkb/E9QC14/entry#E7EZ52-1", "sequence": { "sequence": "MYVKLCNFGKSTDGKPKPKPLPPDSDSSDIYRRVRLYRVVSLVLLVICVLLLIVVLVLFIKLTGMHSCQLTETTLEQECSLKKCQEVYQQPFERALGLCRDCGSGWLRFENTCYFLSETRLTWQKSREECRRKGGDLAVITNERVQMFLSKRAIVNYWIGLSHVGTNQWMWINNTVLTVRYWGDSSSSGECGIMVGEKSAERSWQPASCRLNLQYICQKM", "length": 220, "header": "tr|E7EZ52-1|E9QC14_DANRE Computationally mapped isoform of Uncharacterized protein LOC563797 isoform 1 OS=Danio rerio OX=7955 GN=si:dkey-26c10.5 PE=4 SV=1 CANONICAL=E9QC14-1" }, "locus": {} }, { "isoform_ac": "E9QC14-1", "url": "https://www.uniprot.org/uniprotkb/E9QC14/entry#E9QC14-1", "sequence": { "sequence": "MESQQVVEVELEEIALVEEHNERENEDEQETEADTEKETADEGNVYSSLTDPSEYVYGVPSSTRSYTVNKDSSDIYRRVRLYRVVSLVLLVICVLLLIVVLVLFIKLTGMHSCQLTETTLEQECSLKKCQEVYQQPFERALGLCRDCGSGWLRFENTCYFLSETRLTWQKSREECRRKGGDLAVITNERVQMFLSKRAIVNYWIGLSHVGTNQWMWINNTVLTVRYWGDSSSSGECGIMVGEKSAERSWQPASCRLNLQYICQKM", "length": 265, "header": "tr|E9QC14-1|E9QC14_DANRE Isoform 1 of Uncharacterized protein LOC563797 isoform 1 OS=Danio rerio OX=7955 GN=si:dkey-26c10.5 PE=4 SV=1 CANONICAL=E9QC14-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Contrasted innate responses to two viruses in zebrafish: insights into the ancestral repertoire of vertebrate IFN-stimulated genes.", "journal": "J. Immunol.", "date": "2014", "authors": "Briolat Val\u00e9rie, Jouneau Luc, Carvalho Ralph, Palha Nuno, Langevin Christelle, Herbomel Philippe, Schwartz Olivier, Spaink Herman P, Levraud Jean-Pierre, Boudinot Pierre", "evidence": [ { "database": "UniProtKB", "id": "E7EZ52", "url": "https://www.uniprot.org/uniprotkb/E7EZ52" } ], "reference": [ { "type": "PubMed", "id": "24683187", "url": "https://glygen.org/publication/PubMed/24683187" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7EZ52", "url": "https://www.uniprot.org/uniprotkb/E7EZ52" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] }, { "title": "Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database.", "journal": "BMC Genomics", "date": "2016", "authors": "Pasquier Jeremy, Cabau C\u00e9dric, Nguyen Thaovi, Jouanno Elodie, Severac Dany, Braasch Ingo, Journot Laurent, Pontarotti Pierre, Klopp Christophe, Postlethwait John H, Guiguen Yann, Bobe Julien", "evidence": [ { "database": "UniProtKB", "id": "E7EZ52", "url": "https://www.uniprot.org/uniprotkb/E7EZ52" } ], "reference": [ { "type": "PubMed", "id": "27189481", "url": "https://glygen.org/publication/PubMed/27189481" } ] }, { "title": "Studies Into beta-Glucan Recognition in Fish Suggests a Key Role for the C-Type Lectin Pathway.", "journal": "Front. Immunol.", "date": "2019", "authors": "Petit Jules, Bailey Erin C, Wheeler Robert T, de Oliveira Carlos A F, Forlenza Maria, Wiegertjes Geert F", "evidence": [ { "database": "UniProtKB", "id": "E7EZ52", "url": "https://www.uniprot.org/uniprotkb/E7EZ52" } ], "reference": [ { "type": "PubMed", "id": "30863400", "url": "https://glygen.org/publication/PubMed/30863400" } ] } ], "pathway": [ { "id": "dre:563797", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563797", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "plasma membrane", "id": "GO:0005886", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005886", "evidence": [ { "database": "UniProtKB", "id": "E9QC14", "url": "https://www.uniprot.org/uniprotkb/E9QC14" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 218, "end_pos": 220, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E9QC14", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E9QC14" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 154, "end_pos": 263, "start_aa": "Phe", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 218, "end_pos": 220 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 4 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7EZF8-1", "uniprot_ac": "E7EZF8", "uniprot_id": "E7EZF8_DANRE", "mass": { "chemical_mass": 103169.0, "monoisotopic_mass": 103169.0 }, "refseq": { "ac": "XP_001344451", "name": "little elongation complex subunit 2", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344451" }, "gene_names": [ { "name": "ice2", "type": "recommended", "evidence": [ { "id": "E7EZF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZF8" } ] }, { "name": "ice2", "type": "synonym", "evidence": [ { "id": "XP_001344451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344451" } ] } ], "protein_names": [ { "name": "Little elongation complex subunit 2", "type": "synonym", "evidence": [ { "id": "E7EZF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZF8/entry#names_and_taxonomy" } ] }, { "name": "little elongation complex subunit 2", "type": "synonym", "evidence": [ { "id": "XP_001344451", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344451" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133200) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001344451.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001344451", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344451" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZF8", "url": "https://www.uniprot.org/uniprotkb/E7EZF8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ice2", "url": "https://www.uniprot.org/uniprotkb/E7EZF8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-060306-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060306-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000086670", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000086670", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100005372", "url": "https://www.ncbi.nlm.nih.gov/gene/100005372", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019535", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019535", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100005372", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005372", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7EZF8", "url": "https://www.orthodb.org/?gene=E7EZF8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14633", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14633", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14633:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14633:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10505", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10505", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-6807505", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6807505", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_001344451", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001344451", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EZF8", "url": "https://www.uniprot.org/uniprotkb/E7EZF8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZF8-1", "url": "https://www.uniprot.org/uniprotkb/E7EZF8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-060306-1", "url": "https://zfin.org/ZDB-GENE-060306-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MELKWDVEEAAAATPYVFSRDLFEKFTLAPNVKELFALLHSSGVKPEDAGQKEADAGSQPAKCDEVSDVSNALAADEPTAECKPTQKAKSTPEKNSVVSAFPEPLVPYPCFTKINAKERRSYISMLKSKNYKKASKRLIELVRNETTEFMKYLQEVSRLHADGYNYMPADAIRYTEEYFTACLDHVKSYPQVYGIQEITSLTSLKFVCTISLNFEKQILAMGKTDMVKENAIPANTPLAVDYESVAKVVPPAKKAHSVHNAISSDSNAEKLSATYEPHVCLAKEAFIQLLNNSSELTESWELPVWVRMNPGKGICQSKTAFIDAPLLKTEMSCRERSLLFHEESLKLLFSKTSTRPVFFVTGEELSFKTTPPAEDKTSRSVVTFDDTSMDFETDLTDLESFGESYKPTKKAKDQNKKKTTGLNPNAAPSQLTPSPKKPTDPSDAKKPTSPSENTPETVPEEQAETNTTLDDGGKTAVHGNEESETPSVQCPPVKRPRSLKDDQTEPDSDSDEGRLIIDHIVSPQRPSAQEPAASLEPAAPSPANPPGGKGVKKGVKRQRTSGECDQLGQILKMQDAMLKSTPSKSQEPVKAQVPEEKHPEVKSHSLVKTGVSSYLESRAGQEEDGSLPADTPVMLSAQKKRLLREYLQASAEDELDYDPPAEGSVFYKLYSLLDVLLMVRSSVDIAHPKHDRKTFRAVPVHILPKLEYQLCYGAESLTHTEACQLWAEKLLHSSTESFVSRINAHTSEVAQMQKLPDDWIQNLTCDFKPARCLNTLYHLLKKVSALQEGRYMLVHKPREGFVTIYKASDEAKAVRGVLNLQATHCGTPPVPPGVPWVPLDPTHVLPFHQKHNRPPCTFPPRPPPQPKVKAGPKQRQRKKACRQPQKSNASANPNDSPKTKKKQAARMKLSLLDNMRDKLLKDLQTSEDE", "length": 929, "header": "tr|E7EZF8-1|E7EZF8_DANRE Isoform 1 of Little elongation complex subunit 2 OS=Danio rerio OX=7955 GN=ice2 PE=1 SV=1 CANONICAL=E7EZF8-1" }, "isoforms": [ { "isoform_ac": "E7EZF8-1", "url": "https://www.uniprot.org/uniprotkb/E7EZF8/entry#E7EZF8-1", "sequence": { "sequence": "MELKWDVEEAAAATPYVFSRDLFEKFTLAPNVKELFALLHSSGVKPEDAGQKEADAGSQPAKCDEVSDVSNALAADEPTAECKPTQKAKSTPEKNSVVSAFPEPLVPYPCFTKINAKERRSYISMLKSKNYKKASKRLIELVRNETTEFMKYLQEVSRLHADGYNYMPADAIRYTEEYFTACLDHVKSYPQVYGIQEITSLTSLKFVCTISLNFEKQILAMGKTDMVKENAIPANTPLAVDYESVAKVVPPAKKAHSVHNAISSDSNAEKLSATYEPHVCLAKEAFIQLLNNSSELTESWELPVWVRMNPGKGICQSKTAFIDAPLLKTEMSCRERSLLFHEESLKLLFSKTSTRPVFFVTGEELSFKTTPPAEDKTSRSVVTFDDTSMDFETDLTDLESFGESYKPTKKAKDQNKKKTTGLNPNAAPSQLTPSPKKPTDPSDAKKPTSPSENTPETVPEEQAETNTTLDDGGKTAVHGNEESETPSVQCPPVKRPRSLKDDQTEPDSDSDEGRLIIDHIVSPQRPSAQEPAASLEPAAPSPANPPGGKGVKKGVKRQRTSGECDQLGQILKMQDAMLKSTPSKSQEPVKAQVPEEKHPEVKSHSLVKTGVSSYLESRAGQEEDGSLPADTPVMLSAQKKRLLREYLQASAEDELDYDPPAEGSVFYKLYSLLDVLLMVRSSVDIAHPKHDRKTFRAVPVHILPKLEYQLCYGAESLTHTEACQLWAEKLLHSSTESFVSRINAHTSEVAQMQKLPDDWIQNLTCDFKPARCLNTLYHLLKKVSALQEGRYMLVHKPREGFVTIYKASDEAKAVRGVLNLQATHCGTPPVPPGVPWVPLDPTHVLPFHQKHNRPPCTFPPRPPPQPKVKAGPKQRQRKKACRQPQKSNASANPNDSPKTKKKQAARMKLSLLDNMRDKLLKDLQTSEDE", "length": 929, "header": "tr|E7EZF8-1|E7EZF8_DANRE Isoform 1 of Little elongation complex subunit 2 OS=Danio rerio OX=7955 GN=ice2 PE=1 SV=1 CANONICAL=E7EZF8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100005372", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005372", "resource": "KEGG Pathway" }, { "id": "R-DRE-6807505", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6807505", "resource": "Reactome", "description": "RNA polymerase II transcribes snRNA genes" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZIQ8-1", "protein_name": "Interactor of little elongation complex ELL subunit 2", "gene_name": "Ice2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSSGITMSEPRLNWDVTPKNGLKVFFSPENYKDHSMAPSLKELYILSNRRIGENVSVSANSVENEPAVSSATQAKEKVGMILLPKPRVPYPRFSRFSQREQRTFVDLLVKYAKIPSSSKTVGTNTNEFLQYLDMKKHVNEEVNEFLKFLQNSAKKCAQDYNMLSDEARLFTEQILRACIEQVKKYPEFYTLHEVTSLMGFFPFKIEMGLKLEKTLLVLGSAKFVKTAFPSMPVKLQLSKEDMSSIENPQQQAEAMHCDISKDPNAEKLVSRYHPQIALTSQALFTLLNNHGPSYKEQWEIPVCVQMIAVEGSKPVKVIYINSPLPRKQMTMRERNQIFHEVPLKHIFSKTTSVPVSAVFMDKPEEYTSEVDISTEASECRKIETLENLDLDFDGDVTELETFGVTTTSPSRSPSSESDSSAPIMTDVHTAPKVTAIPVAPAAPVTPAAPVAPVVAPVAPVVAPVAPAAPVTPVTPEASAIPNITDDSRSLCQILMKQLQKEKQLFSGVESGPEACKNKDDQGLEPCAEEGPSANAKSLTQDSEVHRTEEISNESDVGALCTSDERQSVQKNADNPNETATASETADTEKGIPCGSDTDEDCLIIDTESKSNSDGRTAGLGSSPNSSAQASVENQTTTTVSEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPVSRTIPELPLTNSEESKQPSASEQPSATLDASTWPKSSWPSAFQKPKGRLPYELQDYVEDTSEYVAPQEGNFVYKLFSLQDLLLLVRCSVQRVETRPRSKKRKKIRRQFPVYVLPKVEYQGCYGVEALTESELCRFWTESLLHSNCSFYVGHIDAFTSKLFMLEEITSEELKEKLAALKISSLFNILQHILKKLCSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKAHCDLPGVPSSLSVPWVPLDPSYLLPYHIHHGRIPCTFPPKSLRPAAQPKVGATRMPTRNHRNPVSRETKSSCLPVQQVENEGVAQNKRKIM", "length": 997 }, "evidence": [ { "id": "HGNC:29885", "url": "https://alliancegenome.org/gene/HGNC:29885#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q3UZ18-1", "protein_name": "Little elongation complex subunit 2", "gene_name": "Ice2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSSSITMSEPRLNWDVTPKNGLKAFFSPENYKDHSMAPSLKELYILSNRRIGENLSVSASSVENEPAVSSATQAKEKVGMILLPKPRVPYPRFSRFSQREQRTYVDLLAKYAKLPSSSKTVGTNTNEYLQYLDMKKHVNEEVNEFLKFLQNSAKKCAQDYNMLSDEARLFTEQLLRACIEQVKKYPEFYTLHEVTSLMGFFPFKTEMGLKLEKTLLVLGSAKFVKTAFPSMPVKLQLSKEDMSSIETPQQKAEVMHCDISKDPNAEKLVSRYHPQIALTSQALFTLLNNHGPSYKEQWEIPVCVEMIAVEGSKPVKVIYINSPLPRKQMTMRERNQIFHEVPLKHIISKNTSVPVSAVFMDKPEEYTSEVDMPTEAGECRKIETLENLDMDFDGDVTELETFGVTTTSPPRSPSSESDSSAPLMTDVHAVPKIAAVPLAPATPVAPTMPVAPATPVTPTMPMAPATPEASATPNITDDSRSLCQILMKQLQKEKQLFSGVEGGPEGCKNKDDQGLEPCGEEVPSANAKSLTQDNEVHRTEGISKESDVGVLCTNDERQGGQGNANNPNNTATASEAAESEKGIPCGSDTDEDCLIIDTESRSCDGKTADLGSRPNSSAQASAGNQATTTVSEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPVSRKVPELPLTNSEESKQPPASEQPSAALDAAPWPKSSWPSAFQKPKGRLPYELQDYVEDTSEYIAPQEGNFVYKLFSLQDLLLLVRCSIQRVETRPRSKKRKKIRRQFPVYVLPKVEYQGCYGVEALTESELCRFWTESLLHSNCSFYVGHIDAFTSKLFMLEEIASEELKEKLAALKISSLFNILQHILKKLCSLQEGSYLLSHAAEDSSLLIYKTSDGKVTRTAYNLHKAHCDLPGVPSSLSVPWVPLDPSYLLPYHIHHGRVPCTFPPKPLRPAAQAKVGGTRMPTRNHRNPVSMETKSSCLPVQQVENEGVARNKRKIM", "length": 988 }, "evidence": [ { "id": "HGNC:29885", "url": "https://alliancegenome.org/gene/HGNC:29885#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q659A1-1", "protein_name": "Little elongation complex subunit 2", "gene_name": "ICE2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSSKMVISEPGLNWDISPKNGLKTFFSRENYKDHSMAPSLKELRVLSNRRIGENLNASASSVENEPAVSSATQAKEKVKTTIGMVLLPKPRVPYPRFSRFSQREQRSYVDLLVKYAKIPANSKAVGINKNDYLQYLDMKKHVNEEVTEFLKFLQNSAKKCAQDYNMLSDDARLFTEKILRACIEQVKKYSEFYTLHEVTSLMGFFPFRVEMGLKLEKTLLALGSVKYVKTVFPSMPIKLQLSKDDIATIETSEQTAEAMHYDISKDPNAEKLVSRYHPQIALTSQSLFTLLNNHGPTYKEQWEIPVCIQVIPVAGSKPVKVIYINSPLPQKKMTMRERNQIFHEVPLKFMMSKNTSVPVSAVFMDKPEEFISEMDMSCEVNECRKIESLENLYLDFDDDVTELETFGVTTTKVSKSPSPASTSTVPNMTDAPTAPKAGTTTVAPSAPDISANSRSLSQILMEQLQKEKQLVTGMDGGPEECKNKDDQGFESCEKVSNSDKPLIQDSDLKTSDALQLENSQEIETSNKNDMTIDILHADGERPNVLENLDNSKEKTVGSEAAKTEDTVLCSSDTDEECLIIDTECKNNSDGKTAVVGSNLSSRPASPNSSSGQASVGNQTNTACSPEESCVLKKPIKRVYKKFDPVGEILKMQDELLKPISRKVPELPLMNLENSKQPSVSEQLSGPSDSSSWPKSGWPSAFQKPKGRLPYELQDYVEDTSEYLAPQEGNFVYKLFSLQDLLLLVRCSVQRIETRPRSKKRKKIRRQFPVYVLPKVEYQACYGVEALTESELCRLWTESLLHSNSSFYVGHIDAFTSKLFLLEEITSEELKEKLSALKISNLFNILQHILKKLSSLQEGSYLLSHAAEDSSLLIYKASDGKVTRTAYNLYKTHCGLPGVPSSLSVPWVPLDPSLLLPYHIHHGRIPCTFPPKSLDTTTQQKIGGTRMPTRSHRNPVSMETKSSCLPAQQVETEGVAPHKRKIT", "length": 982 }, "evidence": [ { "id": "HGNC:29885", "url": "https://alliancegenome.org/gene/HGNC:29885#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-060306-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-060306-1#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "transcription elongation factor complex", "id": "GO:0008023", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008023", "evidence": [ { "database": "UniProtKB", "id": "E7EZF8", "url": "https://www.uniprot.org/uniprotkb/E7EZF8" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 3, "go_terms": [ { "name": "positive regulation of transcription by RNA polymerase III", "id": "GO:0045945", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0045945", "evidence": [ { "database": "UniProtKB", "id": "E7EZF8", "url": "https://www.uniprot.org/uniprotkb/E7EZF8" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase II", "id": "GO:0042795", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042795", "evidence": [ { "database": "UniProtKB", "id": "E7EZF8", "url": "https://www.uniprot.org/uniprotkb/E7EZF8" } ], "pmid": "" }, { "name": "snRNA transcription by RNA polymerase III", "id": "GO:0042796", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0042796", "evidence": [ { "database": "UniProtKB", "id": "E7EZF8", "url": "https://www.uniprot.org/uniprotkb/E7EZF8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 144, "end_pos": 146, "annotation": "n_glycosylation_sequon" }, { "start_pos": 291, "end_pos": 293, "annotation": "n_glycosylation_sequon" }, { "start_pos": 292, "end_pos": 294, "annotation": "n_glycosylation_sequon" }, { "start_pos": 466, "end_pos": 468, "annotation": "n_glycosylation_sequon" }, { "start_pos": 762, "end_pos": 764, "annotation": "n_glycosylation_sequon" }, { "start_pos": 888, "end_pos": 890, "annotation": "n_glycosylation_sequon" }, { "start_pos": 894, "end_pos": 896, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EZF8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZF8" }, { "id": "PF10505", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10505" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Little elongation complex subunit 2 C-terminal", "eco_id": "ECO_0000259", "start_pos": 656, "end_pos": 860, "start_aa": "Asp", "end_aa": "Pro", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 144, "end_pos": 146 }, { "start_pos": 291, "end_pos": 293 }, { "start_pos": 292, "end_pos": 294 }, { "start_pos": 466, "end_pos": 468 }, { "start_pos": 762, "end_pos": 764 }, { "start_pos": 888, "end_pos": 890 }, { "start_pos": 894, "end_pos": 896 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EZK7-1", "uniprot_ac": "E7EZK7", "uniprot_id": "E7EZK7_DANRE", "mass": { "chemical_mass": 32175.0, "monoisotopic_mass": 32175.0 }, "refseq": { "ac": "XP_001338241", "name": "protein FAM78B", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338241" }, "gene_names": [ { "name": "fam78ba", "type": "recommended", "evidence": [ { "id": "E7EZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZK7" } ] }, { "name": "fam78ba", "type": "synonym", "evidence": [ { "id": "XP_001338241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338241" } ] } ], "protein_names": [ { "name": "Protein FAM78B", "type": "synonym", "evidence": [ { "id": "E7EZK7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZK7/entry#names_and_taxonomy" } ] }, { "name": "protein FAM78B", "type": "synonym", "evidence": [ { "id": "XP_001338241", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338241" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133177) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001338241.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001338241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338241" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZK7", "url": "https://www.uniprot.org/uniprotkb/E7EZK7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fam78ba", "url": "https://www.uniprot.org/uniprotkb/E7EZK7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-140227-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140227-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000063018", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000063018", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100004809", "url": "https://www.ncbi.nlm.nih.gov/gene/100004809", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR029638", "url": "https://www.ebi.ac.uk/interpro/entry/IPR029638", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100004809", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004809", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "ACKPRVR", "url": "https://omabrowser.org/oma/group/ACKPRVR/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EZK7", "url": "https://www.orthodb.org/?gene=E7EZK7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31655", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31655", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31655:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31655:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_001338241", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001338241", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EZK7", "url": "https://www.uniprot.org/uniprotkb/E7EZK7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZK7-1", "url": "https://www.uniprot.org/uniprotkb/E7EZK7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-140227-3", "url": "https://zfin.org/ZDB-GENE-140227-3", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MNILLKFILIFPSLATLTPLISRTMGCIQSIACKPRIRRENIVVYEVSASIDQCPTIIEENSPIVLRYKTPYFRASAGIVMPPVPRNETWTVGWIQACTQMEFFNTYGDIGMSSWELPELREGRVKAISDSDGVSYPWYGNTTETVTLSGPTSKPSRLTVSMNDNFYPSVTWAVPISNSNTPMLTHITRDQSFITWLVALNADTKERIVLQTVRWRMRVDIEVDPSMPLGSRAKLMGRPHQEQPHILSNNEPIPPNALGRPNANDAQVLMWRPRRGQPLVVIPPK", "length": 285, "header": "tr|E7EZK7-1|E7EZK7_DANRE Isoform 1 of Protein FAM78B OS=Danio rerio OX=7955 GN=fam78ba PE=4 SV=1 CANONICAL=E7EZK7-1" }, "isoforms": [ { "isoform_ac": "E7EZK7-1", "url": "https://www.uniprot.org/uniprotkb/E7EZK7/entry#E7EZK7-1", "sequence": { "sequence": "MNILLKFILIFPSLATLTPLISRTMGCIQSIACKPRIRRENIVVYEVSASIDQCPTIIEENSPIVLRYKTPYFRASAGIVMPPVPRNETWTVGWIQACTQMEFFNTYGDIGMSSWELPELREGRVKAISDSDGVSYPWYGNTTETVTLSGPTSKPSRLTVSMNDNFYPSVTWAVPISNSNTPMLTHITRDQSFITWLVALNADTKERIVLQTVRWRMRVDIEVDPSMPLGSRAKLMGRPHQEQPHILSNNEPIPPNALGRPNANDAQVLMWRPRRGQPLVVIPPK", "length": 285, "header": "tr|E7EZK7-1|E7EZK7_DANRE Isoform 1 of Protein FAM78B OS=Danio rerio OX=7955 GN=fam78ba PE=4 SV=1 CANONICAL=E7EZK7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100004809", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100004809", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6AGD7-1", "protein_name": "Family with sequence similarity 78, member B", "gene_name": "Fam78b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MGCIQSITCKARIRRENIVVYDVCATIDQCPTRIEETSPIVLRYKTPYFKASARVVMPPIPRHETWVVGWIQACNQMEFFNTYSDLGMSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSDSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPLQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGPPLVVIPPK", "length": 261 }, "evidence": [ { "id": "MGI:2443050", "url": "https://alliancegenome.org/gene/MGI:2443050#orthology", "database": "AGR" }, { "id": "HGNC:13495", "url": "https://alliancegenome.org/gene/HGNC:13495#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "B0V2R6-1", "protein_name": "Uncharacterized protein LOC796762", "gene_name": "fam78bb", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MGCLQSVACKPRIKRENIVVYDVSATIDHCPTVIEENSPIVLRYKTPYFKASARIVMPPIPRNETWVVGWIQACTQMEFYNTYGDLGMSSWELPELREGLVKAISDSDGLSYPWYGNTTETVTLSGPTSKPSRFTVSMNDNFYPSVTWAVPVSESNVPLLTRIKRDQSFTTWLVALNVTTQEKILLQTVKWRMKVDIAVDPSKPLSSRARLIGRVHQDQPKVLTHMEQIPPNALGKPNANDAQVLMWRPKRGPPLVVIPSK", "length": 261 }, "evidence": [ { "id": "MGI:2443050", "url": "https://alliancegenome.org/gene/MGI:2443050#orthology", "database": "AGR" }, { "id": "HGNC:13495", "url": "https://alliancegenome.org/gene/HGNC:13495#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q5VT40-1", "protein_name": "Protein FAM78B", "gene_name": "FAM78B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGCIQSITCKARIRRENIVVYDVCATIDQCPTRIEETSPIVLRYKTPYFKASARVVMPPIPRHETWVVGWIQACNQMEFFNTYSDLGMSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSDSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPLQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGPPLVVIPPK", "length": 261 }, "evidence": [ { "id": "MGI:2443050", "url": "https://alliancegenome.org/gene/MGI:2443050#orthology", "database": "AGR" }, { "id": "HGNC:13495", "url": "https://alliancegenome.org/gene/HGNC:13495#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-140227-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-140227-3#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BQN5-1", "protein_name": "Protein FAM78B", "gene_name": "Fam78b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGCIQSITCKARIRRENIVVYDVCATIDQCPTRIEETSPIVLRYKTPYFKASARVVMPPIPRHETWVVGWIQACNQMEFFNTYSDLGMSSWELPDLREGRVKAISDSDGVSYPWYGNTTETVTLVGPTNKISRFSVSMNDNFYPSVTWAVPVSDSNVPLLTRIKRDQSFTTWLVAMNTTTKEKIILQTIKWRMRVDIEVDPLQLLGQRARLVGRTQQEQPRILSRMEPIPPNALVKPNANDAQVLMWRPKRGPPLVVIPPK", "length": 261 }, "evidence": [ { "id": "MGI:2443050", "url": "https://alliancegenome.org/gene/MGI:2443050#orthology", "database": "AGR" }, { 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}, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EZM5-1", "uniprot_ac": "E7EZM5", "uniprot_id": "E7EZM5_DANRE", "mass": { "chemical_mass": 16574.0, "monoisotopic_mass": 16574.0 }, "refseq": { "ac": "XP_005155908", "name": "centrosomal protein 15", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155908" }, "gene_names": [ { "name": "cep15", "type": "recommended", "evidence": [ { "id": "E7EZM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZM5" } ] }, { "name": "si:dkey-274m17.3", "type": "synonym", "evidence": [ { "id": "XP_005155908", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155908" }, { "id": "E7EZM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZM5" } ] } ], "protein_names": [ { "name": "Centrosomal protein 15", "type": "synonym", "evidence": [ { "id": "E7EZM5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZM5/entry#names_and_taxonomy" } ] }, { "name": "centrosomal protein 15", "type": "synonym", "evidence": [ { "id": "XP_005155908", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155908" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005155908", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155908" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZM5", "url": "https://www.uniprot.org/uniprotkb/E7EZM5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cep15", "url": "https://www.uniprot.org/uniprotkb/E7EZM5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-110621-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110621-3", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000086324", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000086324", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100148013", "url": "https://www.ncbi.nlm.nih.gov/gene/100148013", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR028006", "url": "https://www.ebi.ac.uk/interpro/entry/IPR028006", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "KEYIPKW", "url": "https://omabrowser.org/oma/group/KEYIPKW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EZM5", "url": "https://www.orthodb.org/?gene=E7EZM5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14286", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14286", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14286:SF2", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14286:SF2", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF15134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF15134", "database": "Pfam", 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"https://www.uniprot.org/uniprotkb/E7EZM5/entry#E7EZM5-1", "sequence": { "sequence": "MASYTVEEFELSQKHEDILGKRALLLQQMEAHYEQQRAKRKQQFLMCQAAKQRNAQILKDLENVEKNLQTRQLLHPNIISLETRYWASVERNLPEWEQYLLGKGQPPLSESEKKLKQQRLKTAQQDPSPAQCRGKPPRPKP", "length": 141, "header": "tr|E7EZM5-1|E7EZM5_DANRE Isoform 1 of Centrosomal protein 15 OS=Danio rerio OX=7955 GN=cep15 PE=4 SV=1 CANONICAL=E7EZM5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JUN2-1", "protein_name": "Centrosomal protein 15", "gene_name": "Cep15", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MTSLFTQEVHLSKRHEEIVSQRLMLLQKMKNKFGDQSTERASLQATETACRRNLQLLQDIDVAEKAFQTKLTPHPQPEMLSLETRYWASVEEHVPKWEQFLLGKALIQYVPVSGRLRMVLKNESWEWLLNSDRLI", "length": 135 }, "evidence": [ { "id": "RGD:1306063", "url": "https://alliancegenome.org/gene/RGD:1306063#orthology", "database": "AGR" }, { "id": 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"organism": "Homo sapiens", "sequence": { "sequence": "MTSLFAQEIRLSKRHEEIVSQRLMLLQQMENKLGDQHTEKASQLQTVETAFKRNLSLLKDIEAAEKSLQTRIHPLPRPEVVSLETRYWASVEEYIPKWEQFLLGRAPYPFAVENQNEAENTIQNEAQR", "length": 128 }, "evidence": [ { "id": "RGD:1306063", "url": "https://alliancegenome.org/gene/RGD:1306063#orthology", "database": "AGR" }, { "id": "MGI:1917937", "url": "https://alliancegenome.org/gene/MGI:1917937#orthology", "database": "AGR" }, { "id": "HGNC:25024", "url": "https://alliancegenome.org/gene/HGNC:25024#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-110621-3", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-110621-3#orthology", "database": "AGR" }, { "id": "E7EZM5", "url": "https://omabrowser.org/oma/group/E7EZM5/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], 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The reference sequence was derived from JBMGRA010000004.1, EH536713.1 and EH557964.1. On May 27, 2016 this sequence version replaced XP_009299257.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001314790", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314790" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZN1", "url": "https://www.uniprot.org/uniprotkb/E7EZN1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "si:ch211-161m3.6", "url": "https://www.uniprot.org/uniprotkb/E7EZN1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-161017-36", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-161017-36", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000091393", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000091393", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100005838", "url": "https://www.ncbi.nlm.nih.gov/gene/100005838", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR013087", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013087", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036236", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036236", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100005838", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100005838", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "FIVKMED", "url": "https://omabrowser.org/oma/group/FIVKMED/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EZN1", "url": "https://www.orthodb.org/?gene=E7EZN1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24409", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24409", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24409:SF331", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24409:SF331", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00096", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00096", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF13465", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF13465", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001314790", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001314790", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EZN1", "url": "https://www.uniprot.org/uniprotkb/E7EZN1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZN1-1", "url": "https://www.uniprot.org/uniprotkb/E7EZN1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-161017-36", "url": "https://zfin.org/ZDB-GENE-161017-36", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAFIKEECEDIKTEDVFIVKMEDAEEHTDPLPVKEESQELDEVEEKGPFENYQHFVTGGQSFHRARTDRTSSQEKVQEIDPISYFICFQCGKGFTQKGSLNRHMRTHTGEKPYSCPLCGKSFNQHGNLEVHMGVHSGETPFACQQCGKSFSRKGNLRYHMRVHTGECPFTCQQCGISFTAKGSLTRHMRIHTGERPYTCSECGESFEQHGSLKVHMRTHTGEKPYTCQQCGKSFDQHGNLKVHLRIHTGEKPYECPQCAKTFDQHGNLSAHENSLRGKAVYVSPVWEQLYSERTP", "length": 295, "header": "tr|E7EZN1-1|E7EZN1_DANRE Isoform 1 of Uncharacterized protein LOC100005838 OS=Danio rerio OX=7955 GN=si:ch211-161m3.6 PE=3 SV=1 CANONICAL=E7EZN1-1" }, "isoforms": [ { "isoform_ac": "E7EZN1-1", "url": "https://www.uniprot.org/uniprotkb/E7EZN1/entry#E7EZN1-1", "sequence": { "sequence": "MAFIKEECEDIKTEDVFIVKMEDAEEHTDPLPVKEESQELDEVEEKGPFENYQHFVTGGQSFHRARTDRTSSQEKVQEIDPISYFICFQCGKGFTQKGSLNRHMRTHTGEKPYSCPLCGKSFNQHGNLEVHMGVHSGETPFACQQCGKSFSRKGNLRYHMRVHTGECPFTCQQCGISFTAKGSLTRHMRIHTGERPYTCSECGESFEQHGSLKVHMRTHTGEKPYTCQQCGKSFDQHGNLKVHLRIHTGEKPYECPQCAKTFDQHGNLSAHENSLRGKAVYVSPVWEQLYSERTP", "length": 295, "header": "tr|E7EZN1-1|E7EZN1_DANRE Isoform 1 of Uncharacterized protein LOC100005838 OS=Danio rerio OX=7955 GN=si:ch211-161m3.6 PE=3 SV=1 CANONICAL=E7EZN1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. 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"https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7EZN1", "url": "https://www.uniprot.org/uniprotkb/E7EZN1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E7EZN1", "url": "https://www.uniprot.org/uniprotkb/E7EZN1" } ], "pmid": "" }, { "name": "regulation of transcription by RNA polymerase II", "id": "GO:0006357", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006357", "evidence": [ { "database": "UniProtKB", "id": "E7EZN1", "url": "https://www.uniprot.org/uniprotkb/E7EZN1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 4, "go_terms": [ { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7EZN1", "url": 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"title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7EZP9-1", "uniprot_ac": "E7EZP9", "uniprot_id": "E7EZP9_DANRE", "mass": { "chemical_mass": 32044.0, "monoisotopic_mass": 32044.0 }, "refseq": { "ac": "XP_068075441", "name": "four and a half LIM domains protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075441" }, "gene_names": [ { "name": "fhl3a", "type": "recommended", "evidence": [ { "id": "E7EZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZP9" } ] }, { "name": "fhl3a", "type": "synonym", "evidence": [ { "id": "XP_068075441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075441" } ] } ], "protein_names": [ { "name": "Four and a half LIM domains protein 3", "type": "recommended", "evidence": [ { "id": "E7EZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZP9/entry#names_and_taxonomy" } ] }, { "name": "four and a half LIM domains protein 3", "type": "synonym", "evidence": [ { "id": "XP_068075441", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075441" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_068075441", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075441" } ] }, { "annotation": "Recruited by SOX15 to FOXK1 promoters where it acts as a transcriptional coactivator of FOXK1.", "evidence": [ { "database": "UniProtKB", "id": "E7EZP9", "url": "https://www.uniprot.org/uniprotkb/E7EZP9#function" }, { "database": "UniProtKB", "id": "ARBA00054878", "url": "https://www.uniprot.org/uniprotkb/ARBA00054878#function" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZP9", "url": "https://www.uniprot.org/uniprotkb/E7EZP9" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "fhl3a", "url": 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"categories": [ "Protein Classification" ] }, { "id": "567097", "url": "https://www.ncbi.nlm.nih.gov/gene/567097", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001781", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001781", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR056807", "url": "https://www.ebi.ac.uk/interpro/entry/IPR056807", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:567097", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567097", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QWHQTCF", "url": "https://omabrowser.org/oma/group/QWHQTCF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EZP9", "url": "https://www.orthodb.org/?gene=E7EZP9", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR24205", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24205", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR24205:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR24205:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00412", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00412", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF25076", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF25076", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_068075441", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_068075441", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EZP9", "url": "https://www.uniprot.org/uniprotkb/E7EZP9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZP9-1", "url": "https://www.uniprot.org/uniprotkb/E7EZP9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-4741", "url": "https://zfin.org/ZDB-GENE-030131-4741", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSERFDCDNCKESLYGRKYIQAEENPYCIPCYDSLFANTCDECKELIGHDSRELFYEDRHYHEHCFRCFRCDRSLADEPFTSQDDALLCNDCYCNEFSSKCVACDKTVMPGTRKLEYAGSTWHEGCFICNSCQQPIGSKSFIPDKDDHYCVPCYENKFAPRCTRCKQALAKGGVTYRDEPWHKECFVCTSCKVQLAGQHFTSRDDSPYCIKCFGNLYAKKCEACNKPITGFGGGKYISFEDRQWHQPCFTCSRCSVSLVGAGFFPEQDEILCRNCNSTL", "length": 279, "header": "tr|E7EZP9-1|E7EZP9_DANRE Isoform 1 of Four and a half LIM domains protein 3 OS=Danio rerio OX=7955 GN=fhl3a PE=4 SV=1 CANONICAL=E7EZP9-1" }, "isoforms": [ { "isoform_ac": "E7EZP9-1", "url": "https://www.uniprot.org/uniprotkb/E7EZP9/entry#E7EZP9-1", "sequence": { "sequence": "MSERFDCDNCKESLYGRKYIQAEENPYCIPCYDSLFANTCDECKELIGHDSRELFYEDRHYHEHCFRCFRCDRSLADEPFTSQDDALLCNDCYCNEFSSKCVACDKTVMPGTRKLEYAGSTWHEGCFICNSCQQPIGSKSFIPDKDDHYCVPCYENKFAPRCTRCKQALAKGGVTYRDEPWHKECFVCTSCKVQLAGQHFTSRDDSPYCIKCFGNLYAKKCEACNKPITGFGGGKYISFEDRQWHQPCFTCSRCSVSLVGAGFFPEQDEILCRNCNSTL", "length": 279, "header": "tr|E7EZP9-1|E7EZP9_DANRE Isoform 1 of Four and a half LIM domains protein 3 OS=Danio rerio OX=7955 GN=fhl3a PE=4 SV=1 CANONICAL=E7EZP9-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:567097", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:567097", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8I6A1C9-1", "protein_name": "Four and a half LIM domains protein 3", "gene_name": "Fhl3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSEAFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNECYCTAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDDDPYCVACFGELFAPKCSSCKRPITGGSGSEGAGKSADVILGEPKGQQCPQTCRANLQPSSRTRWRQVRVLRRPTLAPQLLFLCPLLHLPGGPRLCTRWRPSSVPGLQPSRPLSPGS", "length": 321 }, "evidence": [ { "id": "HGNC:3704", "url": "https://alliancegenome.org/gene/HGNC:3704#orthology", "database": "AGR" }, { "id": "RGD:1307180", "url": "https://alliancegenome.org/gene/RGD:1307180#orthology", "database": "AGR" }, { "id": "MGI:1341092", "url": "https://alliancegenome.org/gene/MGI:1341092#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4741", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4741#orthology", "database": "AGR" }, { "id": "E7EZP9", "url": "https://omabrowser.org/oma/group/E7EZP9/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M1NDX6-1", "protein_name": "Four and a half LIM domains protein 3b", "gene_name": "fhl3b", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSEPFDCESCKESLYGQKYIQVDDKPHCVPCYDRLHANTCHECKELIEHNSRELYHEDRHYHEQCFRCSRCSRSLAKESFTCQEDALVCNNCYCNEFSSNCVACGKTVMPGSKRLEYEDCVWHEECFVCCGCEQPIGAQSFIPDKDEYYCVPCYEGRFAPRCAHCKQTLVQGGVTYRDEPWHKECFLCTGCKVQLAGQPFTTQGEDPYCVKCFSNLYAQKCAACEKPITGFGEGKYVSFEERQWHKPCFKCSVCSLSLVGAGFFPHGSMILCKGCNTKKLFQIVCEQTIE", "length": 290 }, "evidence": [ { "id": "HGNC:3704", "url": "https://alliancegenome.org/gene/HGNC:3704#orthology", "database": "AGR" }, { "id": "RGD:1307180", "url": "https://alliancegenome.org/gene/RGD:1307180#orthology", "database": "AGR" }, { "id": "MGI:1341092", "url": "https://alliancegenome.org/gene/MGI:1341092#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "A0A9J7FF68-1", "protein_name": "Four and a half LIM domains protein 3", "gene_name": "Fhl3", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSPYLNSYGHPGNEEGLLSITTMSEAFDCAKCSESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCTAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCKTPLAGQQFTSRDDDPYCVACFGELFAPKCSSCKRPITGGSSGEAAGGGKYVSFEDRHWHHSCFSCARCSTSLVGQGFVPDGDQVLCQGCSQAGP", "length": 308 }, "evidence": [ { "id": "E7EZP9", "url": "https://omabrowser.org/oma/group/E7EZP9/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "Q13643-1", "protein_name": "Four and a half LIM domains protein 3", "gene_name": "FHL3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSESFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSRDEDPYCVACFGELFAPKCSSCKRPIVGLGGGKYVSFEDRHWHHNCFSCARCSTSLVGQGFVPDGDQVLCQGCSQAGP", "length": 280 }, "evidence": [ { "id": "HGNC:3704", "url": "https://alliancegenome.org/gene/HGNC:3704#orthology", "database": "AGR" }, { "id": "RGD:1307180", "url": "https://alliancegenome.org/gene/RGD:1307180#orthology", "database": "AGR" }, { "id": "MGI:1341092", "url": "https://alliancegenome.org/gene/MGI:1341092#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4741", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4741#orthology", "database": "AGR" }, { "id": "E7EZP9", "url": "https://omabrowser.org/oma/group/E7EZP9/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q3ZBI6-1", "protein_name": "Four and a half LIM domains protein 3", "gene_name": "FHL3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MSEAFDCAKCSESLYGRKYIQTDDGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNDCYCSAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCQTPLAGQQFTSREDDPYCVTCFGELFAPKCSSCKRPITGLGGGKYVSFEDRHWHHSCFSCARCSTSLVGQGFVPDGDQVLCQGCSQAGP", "length": 280 }, "evidence": [ { "id": "E7EZP9", "url": "https://omabrowser.org/oma/group/E7EZP9/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "Q9R059-1", "protein_name": "Four and a half LIM domains protein 3", "gene_name": "Fhl3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSEAFDCAKCNESLYGRKYIQTDSGPYCVPCYDNTFANTCAECQQLIGHDSRELFYEDRHFHEGCFRCCRCQRSLADEPFTCQDSELLCNECYCTAFSSQCSACGETVMPGSRKLEYGGQTWHEHCFLCSGCEQPLGSRSFVPDKGAHYCVPCYENKFAPRCARCSKTLTQGGVTYRDQPWHRECLVCTGCKTPLAGQQFTSRDDDPYCVACFGELFAPKCSSCKRPITGGSGGGEGAGLGGGKYVSFEDRHWHHSCFSCARCSTSLVGQGFVPDGDQVLCQGCSQAGP", "length": 289 }, "evidence": [ { "id": "HGNC:3704", "url": "https://alliancegenome.org/gene/HGNC:3704#orthology", "database": "AGR" }, { "id": "RGD:1307180", "url": "https://alliancegenome.org/gene/RGD:1307180#orthology", "database": "AGR" }, { "id": "MGI:1341092", "url": "https://alliancegenome.org/gene/MGI:1341092#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4741", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4741#orthology", "database": "AGR" }, { "id": "E7EZP9", "url": "https://omabrowser.org/oma/group/E7EZP9/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 3, "go_terms": [ { "name": "actin binding", "id": "GO:0003779", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003779", "evidence": [ { "database": "UniProtKB", "id": "E7EZP9", "url": "https://www.uniprot.org/uniprotkb/E7EZP9" } ], "pmid": "" }, { "name": "zinc ion binding", "id": "GO:0008270", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0008270", "evidence": [ { "database": "UniProtKB", "id": "E7EZP9", "url": "https://www.uniprot.org/uniprotkb/E7EZP9" } ], "pmid": "" }, { "name": "transcription coregulator activity", "id": "GO:0003712", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003712", "evidence": [ { "database": "UniProtKB", "id": "E7EZP9", "url": "https://www.uniprot.org/uniprotkb/E7EZP9" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 3, "go_terms": [ { "name": "nucleus", "id": "GO:0005634", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005634", "evidence": [ { "database": "UniProtKB", "id": "E7EZP9", "url": "https://www.uniprot.org/uniprotkb/E7EZP9" } ], "pmid": "" }, { "name": "stress fiber", "id": "GO:0001725", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001725", "evidence": [ { "database": "UniProtKB", "id": "E7EZP9", "url": "https://www.uniprot.org/uniprotkb/E7EZP9" } ], "pmid": "" }, { "name": "Z disc", "id": "GO:0030018", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030018", "evidence": [ { "database": "UniProtKB", "id": "E7EZP9", "url": "https://www.uniprot.org/uniprotkb/E7EZP9" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "DNA-templated transcription", "id": "GO:0006351", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006351", "evidence": [ { "database": "UniProtKB", "id": "E7EZP9", "url": "https://www.uniprot.org/uniprotkb/E7EZP9" } ], "pmid": "" }, { "name": "actin cytoskeleton organization", "id": "GO:0030036", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030036", "evidence": [ { "database": "UniProtKB", "id": "E7EZP9", "url": "https://www.uniprot.org/uniprotkb/E7EZP9" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EZP9", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZP9" }, { "id": "PS50023", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50023" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "LIM zinc-binding", "eco_id": "ECO_0000259", "start_pos": 38, "end_pos": 98, "start_aa": "Asn", "end_aa": "Ser", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 276, "end_pos": 278 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EZR2-1", "uniprot_ac": "E7EZR2", "uniprot_id": "E7EZR2_DANRE", "mass": { "chemical_mass": 43158.0, "monoisotopic_mass": 43158.0 }, "refseq": { "ac": "XP_690443", "name": "SAM and SH3 domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690443" }, "gene_names": [ { "name": "sash3", "type": "recommended", "evidence": [ { "id": "E7EZR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZR2" } ] }, { "name": "sash3", "type": "synonym", "evidence": [ { "id": "XP_690443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690443" } ] } ], "protein_names": [ { "name": "SAM and SH3 domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "XP_690443", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690443" }, { "id": "E7EZR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZR2/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_690443.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_690443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690443" } ] } ], "disease": [ { "disease_id": "DOID:0061072", "recommended_name": { "id": "DOID:0061072", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0061072", "name": "immunodeficiency 102", "description": "A T cell and NK cell immunodeficiency that is characterized by the onset of recurrent sinopulmonary, mucosal, and other infections in early childhood, usually accompanied by refractory autoimmune cytopenias and that has_material_basis_in hemizygous mutation in the SASH3 gene on chromosome Xq26." }, "synonyms": [ { "id": "MONDO:0024781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024781", "name": "immunodeficiency 102", "description": "An X-linked recessive immunologic disorder characterized by the onset of recurrent sinopulmonary, mucosal, and other infections in early childhood, usually accompanied by refractory autoimmune cytopenias. Affected individuals have bacterial, viral, and fungal infections, as well as hemolytic anemia, thrombocytopenia, lymphopenia, and decreased NK cells. Laboratory studies show defective T-cell proliferation and function, likely due to signaling abnormalities. The disorder may also manifest as a hyperinflammatory state with immune dysregulation." }, { "id": "MONDO:0024781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024781", "name": "IMD102", "description": "" }, { "id": "MONDO:0024781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024781", "name": "SASH3 deficiency", "description": "" }, { "id": "MONDO:0024781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024781", "name": "X-linked CID due to SASH3 deficiency", "description": "" }, { "id": "MONDO:0024781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024781", "name": "X-linked combined immunodeficiency due to SASH3 deficiency", "description": "" }, { "id": "MONDO:0024781", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024781", "name": "immunodeficiency 102", "description": "" }, { "id": "MIM:301082", "resource": "MIM", "url": "https://www.omim.org/entry/301082", "name": "Immunodeficiency 102", "description": "Immunodeficiency 102" } ], "unlinked_id_list": [], "evidence": [ { "id": "0061072", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0061072" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZR2", "url": "https://www.uniprot.org/uniprotkb/E7EZR2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "sash3", "url": "https://www.uniprot.org/uniprotkb/E7EZR2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130411-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130411-1", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000016541", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000016541", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd09493", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd09493", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "561954", "url": "https://www.ncbi.nlm.nih.gov/gene/561954", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001452", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001452", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001660", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001660", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013761", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013761", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR021090", "url": "https://www.ebi.ac.uk/interpro/entry/IPR021090", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036028", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036028", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051725", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051725", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561954", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561954", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "DKEPTQK", "url": "https://omabrowser.org/oma/group/DKEPTQK/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EZR2", "url": "https://www.orthodb.org/?gene=E7EZR2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR12301", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12301", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR12301:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR12301:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00536", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00536", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF07653", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07653", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF12485", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF12485", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_690443", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_690443", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EZR2", "url": "https://www.uniprot.org/uniprotkb/E7EZR2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZR2-1", "url": "https://www.uniprot.org/uniprotkb/E7EZR2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130411-1", "url": "https://zfin.org/ZDB-GENE-130411-1", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLRRKPSNASEKEQSQAQKKKPLQRSASFKDFMKSKPSSPVTNPEPLLNESLFEAAPPEESGKSHGKLGKKWRNVITRTMTRKTSKMVQKALAEEGNESGEDGSMSPMSPTDWTPDLTAGNRTSVCSNSSEDTIHSPLSRQLSGCADRQSLDSGFSQRDSMRLEDSTYMGPFCGRAVVITDFTPSPYDIDCLKLQKGDIIQIIEKPPVGTWTGKLNNKVGSFKFVYVSMLPEEETPPKRKRSHSHGHQKAKPKTLEEVLERIGLTELGSLLSMHGFQSLEDFTGLKESHLNDLNITDPEQRVKILKATELIHDSEDESDAEEQKTEMPRDSGCYESTENLANEREEPQVDSQAEPETDPDTEIKLNAVQEQLEVMKVEESPETQTE", "length": 386, "header": "tr|E7EZR2-1|E7EZR2_DANRE Isoform 1 of SAM and SH3 domain-containing protein 3 OS=Danio rerio OX=7955 GN=sash3 PE=4 SV=1 CANONICAL=E7EZR2-1" }, "isoforms": [ { "isoform_ac": "E7EZR2-1", "url": "https://www.uniprot.org/uniprotkb/E7EZR2/entry#E7EZR2-1", "sequence": { "sequence": "MLRRKPSNASEKEQSQAQKKKPLQRSASFKDFMKSKPSSPVTNPEPLLNESLFEAAPPEESGKSHGKLGKKWRNVITRTMTRKTSKMVQKALAEEGNESGEDGSMSPMSPTDWTPDLTAGNRTSVCSNSSEDTIHSPLSRQLSGCADRQSLDSGFSQRDSMRLEDSTYMGPFCGRAVVITDFTPSPYDIDCLKLQKGDIIQIIEKPPVGTWTGKLNNKVGSFKFVYVSMLPEEETPPKRKRSHSHGHQKAKPKTLEEVLERIGLTELGSLLSMHGFQSLEDFTGLKESHLNDLNITDPEQRVKILKATELIHDSEDESDAEEQKTEMPRDSGCYESTENLANEREEPQVDSQAEPETDPDTEIKLNAVQEQLEVMKVEESPETQTE", "length": 386, "header": "tr|E7EZR2-1|E7EZR2_DANRE Isoform 1 of SAM and SH3 domain-containing protein 3 OS=Danio rerio OX=7955 GN=sash3 PE=4 SV=1 CANONICAL=E7EZR2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561954", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561954", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KHV7-1", "protein_name": "Sterile alpha motif domain-containing protein 5", "gene_name": "SKIP", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MAVSNIVCEWLRALGLAQYAESFLDNGYDDLEICKQVGDPDLDAIGVENPAHRHKLLKSIRSLREKGAASVYFMLNDPNSLSGSMEILCETPPNNELELVLREQLETDGVRLTAHPYSTPPSSCLSDKEEDEIYGFGYGVFAPRVARGGLTQQQQLLQQQTLQTQQSIQQQQQQMQQQQQQLPIVPGQQQQGPHQHQTLPPNVAHLNFVQQNCLSPRSAYFYEFPPTAEGRETKKRTTLARLLKGLKTVNRRDRNNQQNGAQARAANDRLRHFQMINGGAGGQQHSFEETIHRLKVQEAMRKKEKFQREHEEILRDIRQGLLQMSRGEGRMDDTYMYDEALRTGGGMGIAGLGMPLGVGGNGGGGGAAHYAVSALHHQGHWYDEPPYESDPDDFLMAGLNCGPAATIQGGRVRFSNNRESTGVISLRSAGDISLPQRGPPRRGLIVPQQPPNPPTIIPLTHARSHDRESGDYAGSISDLQSVTSRFSTVSIGTNNCTARYRTLSGGIGESPSLSPSPSSDYEDIGVTRGHGCLPPSLLAAKAKKNGLPHGKANTICQKATVHHSGEMRSSAKEIGAFNENGRNFVATKDTSRDFSNSQDNTDRGSMSDQAFACSASSVESLPSASGSSTQALVRPGSPHSSISAEDRTSMASCICKAKALVDSLPNPYDKEALKFKKGDLIDVLSMNASGIWKGRCHGRVGHFKFINVEVLPEQRMKNSSSKTLAAGSRLANSGNGSHNGGPCSVEDLLIRIGLKEYTSVFVLNGYEDLELFKELEPADLDYLGILNQEHRAKLLTAVQLLHDIECSDVDIPGSSSENDEARLNNINMKHGASPFGRRHFPRDSGCYEGSPLPSSQTPTQAVNSTDESNSLDDVVTKCSSEIMKRVESARRCKDNPFKTTLPGGGRLGKKSFLGGNGLMADDTLTRGGLSEKSSDSGVSSSSLSSGPLKSSTXHLPTILAHELLLGVGSGMGMGLGLGTMSHGTTGTLTPHGVATATSPTAHSAPLGNICNTLPHAPSSSGGGGVSSSMASNLPLNRNLVMLRNHLRKNTGGSITGNGGVGASGVGAQLLQDQDDRLEDQ", "length": 1080 }, "evidence": [ { "id": "HGNC:15975", "url": "https://alliancegenome.org/gene/HGNC:15975#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A480KK25-1", "protein_name": "SAM and SH3 domain containing 3", "gene_name": "SASH3", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMVVKALSEEMGDTLEEGSASPTSPDCSLDSPGPEKMALAFSEQEERELPALSRQASTGSELCSPSPGSGSFGEDPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIVEKPPVGTWLGLLNGRLGSFKFIYVDVLPEEAAGPARPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRDEAELASAEEQLHSLSLAGSP", "length": 380 }, "evidence": [ { "id": "E7EZR2", "url": "https://omabrowser.org/oma/group/E7EZR2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "A0JN71-1", "protein_name": "SAM and SH3 domain-containing protein 3", "gene_name": "SASH3", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDESSVPTPEDAEKSGKKLGKKWRAVISRTMNRKTGKKMVKALSEEMGDTLEEGSASPTSPDCSLDSPGPEKMALAFSEQEERELPALSRQASTGSELCSPSPGSGNLGEESTAPQYTGPFCGRARVHTDFTPSPYDRDSLKLQKGDVIQIVEKPPVGTWLGLLNGRMGSFKFIYVDVLPEEAVGPARPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGTESGQEPAVSTVADPKVDIPRDSGCFEGSESGRDEAELAGTEEQLHGLSLSGAP", "length": 380 }, "evidence": [ { "id": "E7EZR2", "url": "https://omabrowser.org/oma/group/E7EZR2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "F7EM42-1", "protein_name": "SAM and SH3 domain containing 3", "gene_name": "Sash3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLRRKPSNASDKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVLTPEDSGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMGDTLEEGSASPTSPDCSLDSPGPEKMALAFSEPEERELLALSRQTSTGSELCSPGPGSGSFIEESPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKLGSFKFIYVDVLPEEAVGPVRPSRRQSKSKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTAGSEEAEEGAESSQEPALHTVSEPKVDIPRDSGCFEGSESGRDEAELTGTEEQLQGLSLAGAP", "length": 381 }, "evidence": [ { "id": "HGNC:15975", "url": "https://alliancegenome.org/gene/HGNC:15975#orthology", "database": "AGR" }, { "id": "MGI:1921381", "url": "https://alliancegenome.org/gene/MGI:1921381#orthology", "database": "AGR" }, { "id": "E7EZR2", "url": "https://omabrowser.org/oma/group/E7EZR2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "O75995-1", "protein_name": "SAM and SH3 domain-containing protein 3", "gene_name": "SASH3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLRRKPSNASEKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVPTPEDAGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMADTLEEGSASPTSPDYSLDSPGPEKMALAFSEQEEHELPVLSRQASTGSELCSPSPGSGSFGEEPPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIIEKPPVGTWLGLLNGKVGSFKFIYVDVLPEEAVGHARPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRDDAELAGTEEQLQGLSLAGAP", "length": 380 }, "evidence": [ { "id": "HGNC:15975", "url": "https://alliancegenome.org/gene/HGNC:15975#orthology", "database": "AGR" }, { "id": "MGI:1921381", "url": "https://alliancegenome.org/gene/MGI:1921381#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130411-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130411-1#orthology", "database": "AGR" }, { "id": "E7EZR2", "url": "https://omabrowser.org/oma/group/E7EZR2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8K352-1", "protein_name": "SAM and SH3 domain-containing protein 3", "gene_name": "Sash3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLRRKPSNASDKEPTQKKKLSLQRSSSFKDFAKSKPSSPVVSEKEFNLDDNIPEDDSGVLTPEDSGKSGKKLGKKWRAVISRTMNRKMGKMMVKALSEEMGDTLEEGSASPTSPDCSLDSPGPEKMALAFTEQEEREPPSLSRQTSTGSELCSPGPGSGSFLEESPAPQYTGPFCGRARVHTDFTPSPYDHDSLKLQKGDVIQIVEKPPVGTWLGLLNGKLGSFKFIYVDVLPEEAVGPVRPSRRQSKGKRPKPKTLHELLERIGLEEHTSTLLLNGYQTLEDFKELRETHLNELNIMDPQHRAKLLTAAELLLDYDTGSEEAEEGAESSQEPVAHTVSEPKVDIPRDSGCFEGSESGRDEAELAGTEEQLQGLSLSGAP", "length": 380 }, "evidence": [ { "id": "HGNC:15975", "url": "https://alliancegenome.org/gene/HGNC:15975#orthology", "database": "AGR" }, { "id": "MGI:1921381", "url": "https://alliancegenome.org/gene/MGI:1921381#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130411-1", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130411-1#orthology", "database": "AGR" }, { "id": "E7EZR2", "url": "https://omabrowser.org/oma/group/E7EZR2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 4, "go_terms": [ { "name": "positive regulation of B cell proliferation", "id": "GO:0030890", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030890", "evidence": [ { "database": "UniProtKB", "id": "E7EZR2", "url": "https://www.uniprot.org/uniprotkb/E7EZR2" } ], "pmid": "" }, { "name": "regulation of intracellular signal transduction", "id": "GO:1902531", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1902531", "evidence": [ { "database": "UniProtKB", "id": "E7EZR2", "url": "https://www.uniprot.org/uniprotkb/E7EZR2" } ], "pmid": "" }, { "name": "positive regulation of adaptive immune response", "id": "GO:0002821", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002821", "evidence": [ { "database": "UniProtKB", "id": "E7EZR2", "url": "https://www.uniprot.org/uniprotkb/E7EZR2" } ], "pmid": "" }, { "name": "positive regulation of immunoglobulin production", "id": "GO:0002639", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0002639", "evidence": [ { "database": "UniProtKB", "id": "E7EZR2", "url": "https://www.uniprot.org/uniprotkb/E7EZR2" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 121, "end_pos": 123, "annotation": "n_glycosylation_sequon" }, { "start_pos": 128, "end_pos": 130, "annotation": "n_glycosylation_sequon" }, { "start_pos": 294, "end_pos": 296, "annotation": "n_glycosylation_sequon" }, { "start_pos": 49, "end_pos": 51, "annotation": "n_glycosylation_sequon" }, { "start_pos": 8, "end_pos": 10, "annotation": "n_glycosylation_sequon" }, { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EZR2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZR2" }, { "id": "PS50002", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50002" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH3", "eco_id": "ECO_0000259", "start_pos": 171, "end_pos": 232, "start_aa": "Pro", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 121, "end_pos": 123 }, { "start_pos": 128, "end_pos": 130 }, { "start_pos": 294, "end_pos": 296 }, { "start_pos": 49, "end_pos": 51 }, { "start_pos": 8, "end_pos": 10 }, { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EZS2-1", "uniprot_ac": "E7EZS2", "uniprot_id": "E7EZS2_DANRE", "mass": { "chemical_mass": 37364.0, "monoisotopic_mass": 37364.0 }, "refseq": { "ac": "XP_005173833", "name": "keratinocyte differentiation factor 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173833" }, "gene_names": [ { "name": "kdf1b", "type": "recommended", "evidence": [ { "id": "E7EZS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZS2" } ] }, { "name": "kdf1b", "type": "synonym", "evidence": [ { "id": "XP_005173833", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173833" } ] } ], "protein_names": [ { "name": "Keratinocyte differentiation factor 1", "type": "synonym", "evidence": [ { "id": "E7EZS2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZS2/entry#names_and_taxonomy" } ] }, { "name": "keratinocyte differentiation factor 1", "type": "synonym", "evidence": [ { "id": "XP_005173833", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173833" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005173833", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005173833" } ] } ], "disease": [ { "disease_id": "DOID:0111652", "recommended_name": { "id": "DOID:0111652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111652", "name": "ectodermal dysplasia 12", "description": "A hypohidrotic ectodermal dysplasia that has_material_basis_in heterozygous mutation in the KDF1 gene on chromosome 1p36.11." }, "synonyms": [ { "id": "DOID:0111652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111652", "name": "ECTD12", "description": "" }, { "id": "DOID:0111652", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0111652", "name": "ectodermal dysplasia 12, hypohidrotic/hair/tooth/nail type", "description": "" }, { "id": "MONDO:0015024", "resource": "MONDO", "url": 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"resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0015024", "name": "ectodermal dysplasia syndrome caused by mutation in KDF1", "description": "" }, { "id": "MIM:617337", "resource": "MIM", "url": "https://www.omim.org/entry/617337", "name": "Ectodermal dysplasia 12, hypohidrotic/hair/tooth/nail type", "description": "Ectodermal dysplasia 12, hypohidrotic/hair/tooth/nail type" } ], "unlinked_id_list": [], "evidence": [ { "id": "0111652", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0111652" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZS2", "url": "https://www.uniprot.org/uniprotkb/E7EZS2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "kdf1b", "url": "https://www.uniprot.org/uniprotkb/E7EZS2", "locus": {} } ], 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"database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8NAX2-1", "protein_name": "Keratinocyte differentiation factor 1", "gene_name": "KDF1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MPRPGHPRPASGPPRLGPWERPTELCLETYDKPPQPPPSRRTRRPDPKDPGHHGPESITFISGSAEPALESPTCCLLWRPWVWEWCRAAFCFRRCRDCLQRCGACVRGCSPCLSTEDSTEGTAEANWAKEHNGVPPSPDRAPPSRRDGQRLKSTMGSSFSYPDVKLKGIPVYPYPRATSPAPDADSCCKEPLADPPPMRHSLPSTFASSPRGSEEYYSFHESDLDLPEMGSGSMSSREIDVLIFKKLTELFSVHQIDELAKCTSDTVFLEKTSKISDLISSITQDYHLDEQDAEGRLVRGIIRISTRKSRARPQTSEGRSTRAAAPTAAAPDSGHETMVGSGLSQDELTVQISQETTADAIARKLRPYGAPGYPASHDSSFQGTDTDSSGAPLLQVYC", "length": 398 }, "evidence": [ { "id": "HGNC:26624", "url": "https://alliancegenome.org/gene/HGNC:26624#orthology", "database": "AGR" }, { "id": "MGI:1916323", "url": "https://alliancegenome.org/gene/MGI:1916323#orthology", "database": "AGR" }, { "id": "RGD:1303271", "url": "https://alliancegenome.org/gene/RGD:1303271#orthology", "database": 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{ "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7EZZ3-1", "uniprot_ac": "E7EZZ3", "uniprot_id": "E7EZZ3_DANRE", "mass": { "chemical_mass": 19830.0, "monoisotopic_mass": 19830.0 }, "refseq": { "ac": "XP_691726", "name": "PRELI domain containing protein 3A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691726" }, "gene_names": [ { "name": "prelid3a", "type": "recommended", "evidence": [ { "id": "E7EZZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZZ3" } ] }, { "name": "prelid3a", "type": "synonym", "evidence": [ { "id": "XP_691726", "database": "RefSeq", "url": 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This record is derived from a genomic sequence (NC_133191) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_691726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691726" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7EZZ3", "url": "https://www.uniprot.org/uniprotkb/E7EZZ3" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "prelid3a", "url": "https://www.uniprot.org/uniprotkb/E7EZZ3", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-130530-654", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-654", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000055288", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000055288", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "563270", "url": "https://www.ncbi.nlm.nih.gov/gene/563270", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006797", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006797", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR037365", "url": "https://www.ebi.ac.uk/interpro/entry/IPR037365", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:563270", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563270", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "MMKIWST", "url": "https://omabrowser.org/oma/group/MMKIWST/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7EZZ3", "url": "https://www.orthodb.org/?gene=E7EZZ3", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR11158", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR11158", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF04707", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF04707", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-6803204", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6803204", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_691726", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_691726", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7EZZ3", "url": "https://www.uniprot.org/uniprotkb/E7EZZ3", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7EZZ3-1", "url": "https://www.uniprot.org/uniprotkb/E7EZZ3-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-130530-654", "url": "https://zfin.org/ZDB-GENE-130530-654", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MKIWSTEHIFSYPWETVIKAAMRKYPNPMNPSVVGVDVLDRNLDTHGRLHSHRLLSTEWGLPGVVKAILGTSRTVTYVKEHSIVDPEEKKMELCSTNITLTNLISVDERLVYRPHPDNPEVTVLTQEAIITVKGVSLSSYLEGLMALTMSANARKGWDAIEWIIQNSEREKCPFV", "length": 175, "header": "tr|E7EZZ3-1|E7EZZ3_DANRE Isoform 1 of PRELI domain containing protein 3A OS=Danio rerio OX=7955 GN=prelid3a PE=4 SV=1 CANONICAL=E7EZZ3-1" }, "isoforms": [ { "isoform_ac": "E7EZZ3-1", "url": "https://www.uniprot.org/uniprotkb/E7EZZ3/entry#E7EZZ3-1", "sequence": { "sequence": "MKIWSTEHIFSYPWETVIKAAMRKYPNPMNPSVVGVDVLDRNLDTHGRLHSHRLLSTEWGLPGVVKAILGTSRTVTYVKEHSIVDPEEKKMELCSTNITLTNLISVDERLVYRPHPDNPEVTVLTQEAIITVKGVSLSSYLEGLMALTMSANARKGWDAIEWIIQNSEREKCPFV", "length": 175, "header": "tr|E7EZZ3-1|E7EZZ3_DANRE Isoform 1 of PRELI domain containing protein 3A OS=Danio rerio OX=7955 GN=prelid3a PE=4 SV=1 CANONICAL=E7EZZ3-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:563270", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:563270", "resource": "KEGG Pathway" }, { "id": "R-DRE-6803204", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-6803204", "resource": "Reactome", "description": "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A287AP45-1", "protein_name": "PRELI domain containing 3A", "gene_name": "PRELID3A", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MRVWSSEHVFRHPWDTVVKAAMRKYPNPMNPCVVGVDVLERSVDARGRLHSHRLLSTEWGLPGLVKAILGTSRTLTYIRERSIVDPVGKKMELCSTNITLTNLVLVSERLVYTPHPEDPGMTVLTQEAVITVKGISLGSYLESLMANTISSNAKKGWAAIEWLIENAEGAAS", "length": 172 }, "evidence": [ { "id": "E7EZZ3", "url": "https://omabrowser.org/oma/group/E7EZZ3/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "D3ZAN9-1", "protein_name": "PRELI domain containing 3A", "gene_name": "Prelid3a", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MRCTDVKVLRDKPPQSGPRDGGGGTAGAPPPRRRAASRRAPNSRPGPAAAAMKIWSSEHVFGHPWDTVIKAAMRKYPNPMNPCVVGVDVLERSVDGYGRLHSLRLLSTEWGLPGLVRAILGANRTLTYIKERSVVDPAARKMELCSTNITLTNLVSVNERLVYTPHPENPEKTVLTQEAIITVKGISLGSYLESLMATTISSNAKKGWAAIEWIIEHSESAIS", "length": 223 }, "evidence": [ { "id": "RGD:1582858", "url": "https://alliancegenome.org/gene/RGD:1582858#orthology", "database": "AGR" }, { "id": "MGI:2442865", "url": "https://alliancegenome.org/gene/MGI:2442865#orthology", "database": "AGR" }, { "id": "HGNC:24639", "url": "https://alliancegenome.org/gene/HGNC:24639#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-654", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-654#orthology", "database": "AGR" }, { "id": "FB:FBgn0029161", "url": "https://alliancegenome.org/gene/FB:FBgn0029161#orthology", "database": "AGR" }, { "id": "SGD:S000002593", "url": "https://alliancegenome.org/gene/SGD:S000002593#orthology", "database": "AGR" }, { "id": "SGD:S000004158", "url": "https://alliancegenome.org/gene/SGD:S000004158#orthology", "database": "AGR" }, { "id": "E7EZZ3", "url": "https://omabrowser.org/oma/group/E7EZZ3/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P35200-1", "protein_name": "Protein UPS2, mitochondrial", "gene_name": "UPS2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKLFQNSYDFNYPWDQVTAANWKKYPNEISTHVIAVDVLRRELKDQGKVLVTERLITVKQGVPKWIMMMLGGTNMSHVREVSVVDLNKKSLTMRSCNLTMCNLLKVYETVTYSPHPDDSANKTLFQQEAQITAYGSIRKLCNKMEDWSVQRFCENAKKGKMGFDAVLQVFSENWEKHVDDLSNQLVSKVNETMEDVKISAGTLLKGTERSGRTILQQNIDLFRDAYNHEN", "length": 230 }, "evidence": [ { "id": "RGD:1582858", "url": "https://alliancegenome.org/gene/RGD:1582858#orthology", "database": "AGR" }, { "id": "MGI:2442865", "url": "https://alliancegenome.org/gene/MGI:2442865#orthology", "database": "AGR" }, { "id": "HGNC:24639", "url": "https://alliancegenome.org/gene/HGNC:24639#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-654", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-654#orthology", "database": "AGR" }, { "id": "FB:FBgn0029161", "url": "https://alliancegenome.org/gene/FB:FBgn0029161#orthology", "database": "AGR" }, { "id": "SGD:S000004158", "url": "https://alliancegenome.org/gene/SGD:S000004158#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q04006-1", "protein_name": "Protein UPS3, mitochondrial", "gene_name": "UPS3", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MKSFQKSYEFDYPWEKVTTANWMKYPNKISTHVIAVDVLRRELKEHGDVLLTERLITIRQNTPHWMSILVGNTNLAYVREVSTVDRRDRSLTMRSCNMTFPHILKCYETVRYVPHPKNPSNVTLFKQDAKFLSGVPTKTFSEKVENWGVKRFSDNAVKGKVGFDSILAMFNDIWKNANE", "length": 179 }, "evidence": [ { "id": "RGD:1582858", "url": "https://alliancegenome.org/gene/RGD:1582858#orthology", "database": "AGR" }, { "id": "MGI:2442865", "url": "https://alliancegenome.org/gene/MGI:2442865#orthology", "database": "AGR" }, { "id": "HGNC:24639", "url": "https://alliancegenome.org/gene/HGNC:24639#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-654", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-654#orthology", "database": "AGR" }, { "id": "FB:FBgn0029161", "url": "https://alliancegenome.org/gene/FB:FBgn0029161#orthology", "database": "AGR" }, { "id": "SGD:S000002593", "url": "https://alliancegenome.org/gene/SGD:S000002593#orthology", "database": "AGR" }, { "id": "E7EZZ3", "url": "https://omabrowser.org/oma/group/E7EZZ3/", "database": "OMA" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q6P9U4-1", "protein_name": "PRELI domain containing protein 3B", "gene_name": "Prelid3b", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHVDPSGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPIRRTMELKSTNISFTNMVSVDERLTYKPHPQDPEKTVLTQEALITVKGVSLSSYLEGLMASTISSNANKGREAMEWVIHKLNAEIEELAASARGSIRTPMAAAAALVDK", "length": 195 }, "evidence": [ { "id": "FB:FBgn0029161", "url": "https://alliancegenome.org/gene/FB:FBgn0029161#orthology", "database": "AGR" }, { "id": "SGD:S000002593", "url": "https://alliancegenome.org/gene/SGD:S000002593#orthology", "database": "AGR" }, { "id": "SGD:S000004158", "url": "https://alliancegenome.org/gene/SGD:S000004158#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N945-1", "protein_name": "PRELI domain-containing protein 2", "gene_name": "PRELID2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MGVSVDVHQVYKYPFEQVVASFLRKYPNPMDKNVISVKIMEEKRDESTGVIYRKRIAICQNVVPEILRKSLSTLVILCWKKVSILKVPNIQLEEESWLNPRERNMAIRSHCLTWTQYASMKEESVFRESMENPNWTEFIQRGRISITGVGFLNCVLETFASTFLRQGAQKGIRIMEMLLKEQCGAPLAE", "length": 189 }, "evidence": [ { "id": "SGD:S000002593", "url": "https://alliancegenome.org/gene/SGD:S000002593#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8VE85-1", "protein_name": "PRELI domain containing protein 3A", "gene_name": "Prelid3a", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIWSSEHVFGHPWDTVIKAAMRKYPNPMNPCVVGVDVLERSVDGCGRLHSLRLLSTEWGLPGLVRAILGANRTLTYIKERSVVDPAARKMELCSTNITLTNLVSVNERLVYTPHPENPEKTVLTQEAIITVKGISLGSYLESLMATTISSNAKKGWAAIEWIIEHSESAIS", "length": 172 }, "evidence": [ { "id": "RGD:1582858", "url": "https://alliancegenome.org/gene/RGD:1582858#orthology", "database": "AGR" }, { "id": "MGI:2442865", "url": "https://alliancegenome.org/gene/MGI:2442865#orthology", "database": "AGR" }, { "id": "HGNC:24639", "url": "https://alliancegenome.org/gene/HGNC:24639#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-654", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-654#orthology", "database": "AGR" }, { "id": "FB:FBgn0029161", "url": "https://alliancegenome.org/gene/FB:FBgn0029161#orthology", "database": "AGR" }, { "id": "SGD:S000002593", "url": "https://alliancegenome.org/gene/SGD:S000002593#orthology", "database": "AGR" }, { "id": "SGD:S000004158", "url": "https://alliancegenome.org/gene/SGD:S000004158#orthology", "database": "AGR" }, { "id": "E7EZZ3", "url": "https://omabrowser.org/oma/group/E7EZZ3/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q96N28-1", "protein_name": "PRELI domain containing protein 3A", "gene_name": "PRELID3A", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIWSSEHVFGHPWDTVIQAAMRKYPNPMNPSVLGVDVLQRRVDGRGRLHSLRLLSTEWGLPSLVRAILGTSRTLTYIREHSVVDPVEKKMELCSTNITLTNLVSVNERLVYTPHPENPEMTVLTQEAIITVKGISLGSYLESLMANTISSNAKKGWAAIEWIIEHSESAVS", "length": 172 }, "evidence": [ { "id": "RGD:1582858", "url": "https://alliancegenome.org/gene/RGD:1582858#orthology", "database": "AGR" }, { "id": "MGI:2442865", "url": "https://alliancegenome.org/gene/MGI:2442865#orthology", "database": "AGR" }, { "id": "HGNC:24639", "url": "https://alliancegenome.org/gene/HGNC:24639#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-654", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-654#orthology", "database": "AGR" }, { "id": "FB:FBgn0029161", "url": "https://alliancegenome.org/gene/FB:FBgn0029161#orthology", "database": "AGR" }, { "id": "SGD:S000002593", "url": "https://alliancegenome.org/gene/SGD:S000002593#orthology", "database": "AGR" }, { "id": "SGD:S000004158", "url": "https://alliancegenome.org/gene/SGD:S000004158#orthology", "database": "AGR" }, { "id": "E7EZZ3", "url": "https://omabrowser.org/oma/group/E7EZZ3/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q9CYY7-1", "protein_name": "PRELI domain containing protein 3B", "gene_name": "Prelid3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHVDPSGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPVTRTMELKSTNISFTNMVSVDERLTYKPHLQDPEKTVLTQEALITVKGVSLSSYLEGLMASTISSNASKGREAMEWVIHKLNAEIEELAASARGSIRTPMAAAAALVDK", "length": 195 }, "evidence": [ { "id": "FB:FBgn0029161", "url": "https://alliancegenome.org/gene/FB:FBgn0029161#orthology", "database": "AGR" }, { "id": "SGD:S000002593", "url": "https://alliancegenome.org/gene/SGD:S000002593#orthology", "database": "AGR" }, { "id": "SGD:S000004158", "url": "https://alliancegenome.org/gene/SGD:S000004158#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9V3U9-1", "protein_name": "Protein slowmo", "gene_name": "slmo", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MKIWTSEHIFNHPWETVTQAAWRKYPNPMTPSIIGTDVVERRVVDGVLHTHRLVQSKWYFPKWTHALIGTAKTCFASERSTVDPERKQMVLKTNNLTFCRNISVDEVLYYEPHPSDASKTLLKQEATVTVFGVPLSHYMEDLLTSTISTNAGKGRQGLEWVIGLINTEVKGIARGTDELLHNTRRSIDEVTESARKSMDEISAQAAKAAKAMHIT", "length": 215 }, "evidence": [ { "id": "RGD:1582858", "url": "https://alliancegenome.org/gene/RGD:1582858#orthology", "database": "AGR" }, { "id": "MGI:2442865", "url": "https://alliancegenome.org/gene/MGI:2442865#orthology", "database": "AGR" }, { "id": "HGNC:24639", "url": "https://alliancegenome.org/gene/HGNC:24639#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-130530-654", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-130530-654#orthology", "database": "AGR" }, { "id": "FB:FBgn0029161", "url": "https://alliancegenome.org/gene/FB:FBgn0029161#orthology", "database": "AGR" }, { "id": "SGD:S000002593", "url": "https://alliancegenome.org/gene/SGD:S000002593#orthology", "database": "AGR" }, { "id": "SGD:S000004158", "url": "https://alliancegenome.org/gene/SGD:S000004158#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9Y3B1-1", "protein_name": "PRELI domain containing protein 3B", "gene_name": "PRELID3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIWTSEHVFDHPWETVTTAAMQKYPNPMNPSVVGVDVLDRHIDPSGKLHSHRLLSTEWGLPSIVKSLIGAARTKTYVQEHSVVDPVEKTMELKSTNISFTNMVSVDERLIYKPHPQDPEKTVLTQEAIITVKGVSLSSYLEGLMASTISSNASKGREAMEWVIHKLNAEIEELTASARGTIRTPMAAAAFAEK", "length": 194 }, "evidence": [ { "id": "FB:FBgn0029161", "url": "https://alliancegenome.org/gene/FB:FBgn0029161#orthology", "database": "AGR" }, { "id": "SGD:S000002593", "url": "https://alliancegenome.org/gene/SGD:S000002593#orthology", "database": "AGR" }, { "id": "SGD:S000004158", "url": "https://alliancegenome.org/gene/SGD:S000004158#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "phosphatidic acid transfer activity", "id": "GO:1990050", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:1990050", "evidence": [ { "database": "UniProtKB", "id": "E7EZZ3", "url": "https://www.uniprot.org/uniprotkb/E7EZZ3" } ], "pmid": "" } ] }, { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "mitochondrial intermembrane space", "id": "GO:0005758", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005758", "evidence": [ { "database": "UniProtKB", "id": "E7EZZ3", "url": "https://www.uniprot.org/uniprotkb/E7EZZ3" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "phospholipid transport", "id": "GO:0015914", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0015914", "evidence": [ { "database": "UniProtKB", "id": "E7EZZ3", "url": "https://www.uniprot.org/uniprotkb/E7EZZ3" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 97, "end_pos": 99, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7EZZ3", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7EZZ3" }, { "id": "PS50904", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50904" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "PRELI/MSF1", "eco_id": "ECO_0000259", "start_pos": 1, "end_pos": 172, "start_aa": "Met", "end_aa": "Cys", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 97, "end_pos": 99 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", 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"table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F0A4-1", "uniprot_ac": "E7F0A4", "uniprot_id": "E7F0A4_DANRE", "mass": { "chemical_mass": 34467.0, "monoisotopic_mass": 34467.0 }, "refseq": { "ac": "XP_005161694", "name": "uncharacterized protein", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161694" }, "gene_names": [ { "name": "LOC101882211", "type": "recommended", "evidence": [ { "id": "E7F0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0A4" } ] }, { "name": "LOC101882211", "type": "synonym", "evidence": [ { "id": "XP_005161694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161694" } ] } ], "protein_names": [ { "name": "Ig-like domain-containing protein", "type": "recommended", "evidence": [ { "id": "E7F0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0A4/entry#names_and_taxonomy" } ] }, { "name": "uncharacterized protein", "type": "synonym", "evidence": [ { "id": "XP_005161694", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161694" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133197) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005161694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161694" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F0A4", "url": "https://www.uniprot.org/uniprotkb/E7F0A4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "LOC101882211", "url": "https://www.uniprot.org/uniprotkb/E7F0A4", "locus": {} } ], "crossref": [ { "id": "ENSDARG00000090882", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000090882", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "101882211", "url": "https://www.ncbi.nlm.nih.gov/gene/101882211", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR003599", "url": "https://www.ebi.ac.uk/interpro/entry/IPR003599", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR007110", "url": "https://www.ebi.ac.uk/interpro/entry/IPR007110", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013106", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013106", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013783", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013783", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036179", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036179", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:101882211", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882211", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7F0A4", "url": "https://www.orthodb.org/?gene=E7F0A4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21063:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21063:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07686", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07686", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005161694", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005161694", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7F0A4", "url": "https://www.uniprot.org/uniprotkb/E7F0A4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0A4-1", "url": "https://www.uniprot.org/uniprotkb/E7F0A4-1", "database": "UniProtKB", "categories": [ "Protein" ] } ], "sequence": { "sequence": "MLMRRPPFFNKITHLRFPVDKNQTMSSLFLILLSIRFILPCHGDSAAETILAKEGQSVNLDTGVEKTQQDRIRWYFKDTRIAQINGDPSKTCTDVQCNEGNENFRDRLKLDHQTGSLTIMNIRNTDAGDYQLKFYSSNSISEKTFSVSIHGVPAAFKMDKSVKEGESFTLDPSARINPNDMATWFFNNTFITKITLPANKICTEDECKEKFGDRLEVDHQTGSLTITKAKTTDSGLYEVEISSHSNRQRRSISSMKSFNVNVIGSSSVLVAGICVAFLLVSALLGVIYFRHRRVIRENRNSMLW", "length": 304, "header": "tr|E7F0A4-1|E7F0A4_DANRE Isoform 1 of Ig-like domain-containing protein OS=Danio rerio OX=7955 GN=LOC101882211 PE=4 SV=3 CANONICAL=E7F0A4-1" }, "isoforms": [ { "isoform_ac": "E7F0A4-1", "url": "https://www.uniprot.org/uniprotkb/E7F0A4/entry#E7F0A4-1", "sequence": { "sequence": "MLMRRPPFFNKITHLRFPVDKNQTMSSLFLILLSIRFILPCHGDSAAETILAKEGQSVNLDTGVEKTQQDRIRWYFKDTRIAQINGDPSKTCTDVQCNEGNENFRDRLKLDHQTGSLTIMNIRNTDAGDYQLKFYSSNSISEKTFSVSIHGVPAAFKMDKSVKEGESFTLDPSARINPNDMATWFFNNTFITKITLPANKICTEDECKEKFGDRLEVDHQTGSLTITKAKTTDSGLYEVEISSHSNRQRRSISSMKSFNVNVIGSSSVLVAGICVAFLLVSALLGVIYFRHRRVIRENRNSMLW", "length": 304, "header": "tr|E7F0A4-1|E7F0A4_DANRE Isoform 1 of Ig-like domain-containing protein OS=Danio rerio OX=7955 GN=LOC101882211 PE=4 SV=3 CANONICAL=E7F0A4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:101882211", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:101882211", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 187, "end_pos": 189, "annotation": "n_glycosylation_sequon" }, { "start_pos": 22, "end_pos": 24, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F0A4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0A4" }, { "id": "PS50835", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50835" } ], "ann_type": 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"sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F0B6-1", "uniprot_ac": "E7F0B6", "uniprot_id": "E7F0B6_DANRE", "mass": { "chemical_mass": 54900.0, "monoisotopic_mass": 54900.0 }, "refseq": { "ac": "XP_001920873", "name": "CDK5 and ABL1 enzyme substrate 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001920873" }, "gene_names": [ { "name": "cables2b", "type": "recommended", "evidence": [ { "id": "E7F0B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0B6" } ] }, { "name": "cables2b", "type": "synonym", "evidence": [ { "id": "XP_001920873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001920873" } ] } ], "protein_names": [ { "name": "CDK5 and ABL1 enzyme substrate 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_001920873", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001920873" }, { "id": "E7F0B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0B6/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133198) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Aug 1, 2013 this sequence version replaced XP_001920873.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_001920873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001920873" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F0B6", "url": "https://www.uniprot.org/uniprotkb/E7F0B6" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "cables2b", "url": "https://www.uniprot.org/uniprotkb/E7F0B6", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090313-249", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-249", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000017154", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000017154", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "564291", "url": "https://www.ncbi.nlm.nih.gov/gene/564291", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006671", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006671", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR012388", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012388", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036915", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036915", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564291", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564291", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "QIPMSRS", "url": "https://omabrowser.org/oma/group/QIPMSRS/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F0B6", "url": "https://www.orthodb.org/?gene=E7F0B6", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22896", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22896", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22896:SF3", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22896:SF3", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00134", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00134", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_001920873", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_001920873", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58INY7", "url": "https://www.uniprot.org/uniprotkb/A0AC58INY7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INY7-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INY7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INZ1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INZ1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58INZ1-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58INZ1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0B6", "url": "https://www.uniprot.org/uniprotkb/E7F0B6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0B6-1", "url": "https://www.uniprot.org/uniprotkb/E7F0B6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090313-249", "url": "https://zfin.org/ZDB-GENE-090313-249", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAAAACSTQSTLNPCTGKLHREHLRKNKDSRRRQAALLFLTNISLDGRPVRNNVIATAPSDAEFQCADIATAVNELSAAASSDGTFSSLPVPRLGLLGVPPILVLPSDSGFSNAGSSEMFLERTRGSFSSQSNLLSPCSLQPTPLGPRKSPTLLSVQSCGSSLDSRPRSRNASGSPRPRSMKKIHFIKNMRQYDTRGSRIVLICAKRSLCAAFSVLPYGESFHISDPLLDAQRRRHSSGGISTTLEMLPGLEGVELGLYGRTVSYAQFLYPTNALDRHKPSVDLTLPLPFSRNSIPRSYPSSRLNSTVGLDLGLEDSDYDPNMLSDPQWPCGKHKRVLIFASYMTTVIEYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKREIRLVGEESCLQPVTIAMAFVYFEKLVLQGRLNKQNRKLVAAACLLLAAKISSDLKKQEVKQLIDKLEERFRISRRELIAFEFTILVALEMALYLPESKVMPHYRQLVQQT", "length": 494, "header": "tr|E7F0B6-1|E7F0B6_DANRE Isoform 1 of CDK5 and ABL1 enzyme substrate 2 isoform X1 OS=Danio rerio OX=7955 GN=cables2b PE=3 SV=1 CANONICAL=E7F0B6-1" }, "isoforms": [ { "isoform_ac": "A0AC58INY7-1", "url": "https://www.uniprot.org/uniprotkb/E7F0B6/entry#A0AC58INY7-1", "sequence": { "sequence": "MAAAACSTQSTLNPCTGKLHREHLRKNKDSRRRQAALLFLTNISLDGRPVRNNVIATAPSDAEFQCADIATAVNELSAAASSDGTFSSLPVPRLGLLGVPPILVLPSDSGFSNAGSSEMFLERTRGSFSSQSNLLSPCSLQPTPLGPRKSPTLLSVQSCGSSLDSRPRSRNASGSPRPRSMKKIHFIKNMRQYDTRGSRIVLICAKRSLCAAFSVLPYGESFHISDPLLDAQRRRHSSGGISTTLEMLPGLEGVELGLYGRTVSYAQFLYPTNALDRHKPSVDLTLPLPFSRNSIPRSYPSSRLNSTVGLDLGLEDSDYDPNMLSDPQWPCGKHKRVLIFASYMTQINTLYPTDFIADHWIIPMTHMCTLIHSNLFSLLHI", "length": 381, "header": "tr|A0AC58INY7-1|A0AC58INY7_DANRE Computationally mapped isoform of CDK5 and ABL1 enzyme substrate 2 isoform X2 OS=Danio rerio OX=7955 GN=cables2b PE=4 SV=1 CANONICAL=E7F0B6-1" }, "locus": {} }, { "isoform_ac": "A0AC58INZ1-1", "url": "https://www.uniprot.org/uniprotkb/E7F0B6/entry#A0AC58INZ1-1", "sequence": { "sequence": "MLPGLEGVELGLYGRTVSYAQFLYPTNALDRHKPSVDLTLPLPFSRNSIPRSYPSSRLNSTVGLDLGLEDSDYDPNMLSDPQWPCGKHKRVLIFASYMTTVIEYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKREIRLVGEESCLQPVTIAMAFVYFEKLVLQGRLNKQNRKLVAAACLLLAAKISSDLKKQEVKQLIDKLEERFRISRRELIAFEFTILVALEMALYLPESKVMPHYRQLVQQT", "length": 248, "header": "tr|A0AC58INZ1-1|A0AC58INZ1_DANRE Computationally mapped isoform of CDK5 and ABL1 enzyme substrate 2 isoform X3 OS=Danio rerio OX=7955 GN=cables2b PE=3 SV=1 CANONICAL=E7F0B6-1" }, "locus": {} }, { "isoform_ac": "E7F0B6-1", "url": "https://www.uniprot.org/uniprotkb/E7F0B6/entry#E7F0B6-1", "sequence": { "sequence": "MAAAACSTQSTLNPCTGKLHREHLRKNKDSRRRQAALLFLTNISLDGRPVRNNVIATAPSDAEFQCADIATAVNELSAAASSDGTFSSLPVPRLGLLGVPPILVLPSDSGFSNAGSSEMFLERTRGSFSSQSNLLSPCSLQPTPLGPRKSPTLLSVQSCGSSLDSRPRSRNASGSPRPRSMKKIHFIKNMRQYDTRGSRIVLICAKRSLCAAFSVLPYGESFHISDPLLDAQRRRHSSGGISTTLEMLPGLEGVELGLYGRTVSYAQFLYPTNALDRHKPSVDLTLPLPFSRNSIPRSYPSSRLNSTVGLDLGLEDSDYDPNMLSDPQWPCGKHKRVLIFASYMTTVIEYVKPSDLKKDMNETFKEKFPHIKLTLSKIRSLKREIRLVGEESCLQPVTIAMAFVYFEKLVLQGRLNKQNRKLVAAACLLLAAKISSDLKKQEVKQLIDKLEERFRISRRELIAFEFTILVALEMALYLPESKVMPHYRQLVQQT", "length": 494, "header": "tr|E7F0B6-1|E7F0B6_DANRE Isoform 1 of CDK5 and ABL1 enzyme substrate 2 isoform X1 OS=Danio rerio OX=7955 GN=cables2b PE=3 SV=1 CANONICAL=E7F0B6-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:564291", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564291", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0B4KF19-1", "protein_name": "Cyclin N-terminal domain-containing protein", "gene_name": "Cables1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MASSLNKTRHRRRLAAISFLSNISLDGTHRDTKFGATFGSSLLCNQNKNPSSLGLGSGGFHPHYQQHHHQRSHSATHHNHQKRHHTQQQQQQQQQQHTQQQQQQQQHQQQHQQQQQHQNGALCSPLLCSADVHMGIDGGIGLGLGLEDCTTGASDGDGHFSETENMGQYLMNVLPAADHNRSSIVPAERRNIKRPTSSGRHNHQAPGNGNMGNKLQQQQQQQHKLQQQQRQARSCAAGSGGSGAESGSDSDSVKIPLKVSNLGSGGGVAGGAGSKLLPLRERTFSNGASDQNLQPERRARLNTAPGMRVGSNSSIAMGGGLKRTYVLSGSSVSHITDDSSTESLTPAGNYAGSFRNSLSKSVQISDSRRGTSGQPLGLGQARDERMVLVSRKIPFFIFSSLPYYKGKNGRAEFRKEDRRRRNPSTSRPLSSINDAPFDPFDLLGIQKAESGQDISYGHLLIPSRQYEKERKKHGNASANPSIFENQMEITSTAALKNHGIARCFTYENNNRNSATSPTPDMKLDMDIESVILGGDSSRGQVYSASILDDPELIAGKHRTLLTFTSYMTSVIDYVRPSDLKKELNDKFREKFPTIQLTLSKLRSIKREMRRINKLDSRIDLVTISQAYVYFEKLILANLINKSNRKLCAGACLLLSAKMNDVKGDALKSLIEKTESVFRLNRKELISSEFAVLVALEFSLHVNRHEVLPHYQRLLYESXDWPKRCAEKSFLAAAQAVQQLCRKGSRK", "length": 746 }, "evidence": [ { "id": "HGNC:16143", "url": "https://alliancegenome.org/gene/HGNC:16143#orthology", "database": "AGR" }, { "id": "MGI:2182335", "url": "https://alliancegenome.org/gene/MGI:2182335#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "A0A8I6A922-1", "protein_name": "Cdk5 and Abl enzyme substrate 2", "gene_name": "Cables2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQARRGQWAAARRRGAAAHSSMAAAAAGGAPGPAPGPARPAPAARNPPAVPRRRGDSRRRQAALFFLNNISLDGRPPSLGPGGEKPLPPPPPPTEAREAPAPPPAPPGGLPGLPARPAPQGLLSPTTAPASLGLDGQRQRRRVTSQRCSLEFLEDAVGCASVQRTKHASGSPRHKGLKKTHFIKNMRQYDTKNSRIVLICAKRSLCAAFSVLPYGEGLRISDLRVDSQKQRHPSGGGGGVSVSSEMVFELEGVELGADGKVVSYAKFLYPTNALVTHKNDSHGLLPQPRPSIPRAPPGSRHKPVPTKSTPAGTELGSDGGDAVEYNPNLLDDPQWPCGKHKRVLIFASYMTTVIEYVKPADLKKDMNETFREKFPHIKLTLSKIRSLKREMRNLSEECSLEPVTVSMAYVYFEKLALQGKLNKQNRKLCAGACVLLAAKISSDLRKSEVKQLIDVSVRSWRKGSGSTGRISLDLSSRCLWLWNWPCTSRRTKYYLTTDASPSSSSPEQCTPQGACFGRKASSLARALTSSVPVLPLVTALAPQSRAALSFPWKEALLLFWSVPHLHLEALLRVFLKQMNIVGLGLLFMCLRPAWFMLSILRSSFHFA", "length": 607 }, "evidence": [ { "id": "HGNC:16143", "url": "https://alliancegenome.org/gene/HGNC:16143#orthology", "database": "AGR" }, { "id": "MGI:2182335", "url": "https://alliancegenome.org/gene/MGI:2182335#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "A0A8M9Q830-1", "protein_name": "CDK5 and ABL1 enzyme substrate 2 isoform X1", "gene_name": "cables2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MAAAACGPRGCPRTNSAKPHKELLRKSRDSRRRQAALLFLTNISLDGRPVYNLSNGLVGPREVDSRCVDVGAAVAGLPLSTTSSYGTFTQVSSSISGGAATPIPRTNVNTYPAPMSPPPALNQGSSDVFTEDGRSDPLSVQAPPLSPTAGPRNTALGSSKSPSQFPSSNPLPDPRQRTRNLSGSPGPKVSKKVHFIKNMRQYDTRGSRVVLICAKRSLCAAFSVLPYGESYHISDSKLEAQRQRHSSGGGSDMVPGLEGVEVDFGKTVSYARFLLPTNALVRLKSSGQTDISTAQMPMSRNRINGQKNFTPSRISSTIGQDTGVDELSEYDPNLLSDPQWPCGKHKRVLIFASYVTTVIEYVKPSDLKKDMNETFKEKFPHIKLTFSKIRSLKREMRSVSEECGLQPVTIAMAYVYFEKLVLQGRLNKHNRKLVSAACVLLAAKISSDLKKQEVKQLIDRLEERFRINRKELISLEFTVLVALEMALYLPDSKVMPHYRRLVQQG", "length": 505 }, "evidence": [ { "id": "HGNC:16143", "url": "https://alliancegenome.org/gene/HGNC:16143#orthology", "database": "AGR" }, { "id": "MGI:2182335", "url": "https://alliancegenome.org/gene/MGI:2182335#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q8K3M5-1", "protein_name": "CDK5 and ABL1 enzyme substrate 2", "gene_name": "Cables2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAAAAAGGAPGPAPGPSRPAPAARNPPAVPRRRGDSRRRQAALFFLNNISLDGRPPSLGPGGEKPAPPPPPPTEAREAPAPPPAPPGGLPGLPARPAPQGLLSPTTAPAGLGLDGQRQRRRVTSQRCSLEFLEDTVGCASVQRTKHASGSPRHKGLKKTHFIKNMRQYDTKNSRIVLICAKRSLCAAFSVLPYGEGLRISDLRVDSQKQRHPSGGVSVSSEMVFELEGVELGADGKVVSYAKFLYPTNALVIHKNDSHGLLPQPRPSIPRAPPGSRHKPVPTKSTPAGTELGSDGGDAVEYNPNLLDDPQWPCGKHKRVLIFASYMTTVIEYVKPADLKKDMNETFREKFPHIKLTLSKIRSLKREMRNLSEECSLEPVTVSMAYVYFEKLVLQGKLNKQNRKLCAGACVLLAAKISSDLRKSEVKQLIDKLEERFRFNRKDLIGFEFTVLVALELALYLPENQVLPHYRRLTQQF", "length": 476 }, "evidence": [ { "id": "HGNC:16143", "url": "https://alliancegenome.org/gene/HGNC:16143#orthology", "database": "AGR" }, { "id": "MGI:2182335", "url": "https://alliancegenome.org/gene/MGI:2182335#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-249", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-249#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9BTV7-1", "protein_name": "CDK5 and ABL1 enzyme substrate 2", "gene_name": "CABLES2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MAAAAAGGAPGPAPGPAGPPPPAAPTSAARAPPQALRRRGDSRRRQAALFFLNNISLDGRPPSLGPGGEKPPPPPAEAREPPAPPPPEPPTGLPARTPAPQGLLSPTQVPTGLGLDGQRQRKRVTSQRCSLEFLEDAVGCAPAQRTKHTSGSPRHKGLKKTHFIKNMRQYDTRNSRIVLICAKRSLCAAFSVLPYGEGLRISDLRVDSQKQRHPSGGVSVSSEMVFELEGVELGADGKVVSYAKFLYPTNALVTHKSDSHGLLPTPRPSVPRTLPGSRHKPAPTKSAPASTELGSDVGDTLEYNPNLLDDPQWPCGKHKRVLIFASYMTTVIEYVKPSDLKKDMNETFREKFPHVKLTLSKIRSLKREMRSLSEECSLEPVTVAMAYVYFEKLVLQGKLSKQNRKLCAGACVLLAAKISSDLRKSGVTQLIDKLEERFRFNRRDLIGFEFTVLVALELALYLPENQVLPHYRRLTQQF", "length": 478 }, "evidence": [ { "id": "HGNC:16143", "url": "https://alliancegenome.org/gene/HGNC:16143#orthology", "database": "AGR" }, { "id": "MGI:2182335", "url": "https://alliancegenome.org/gene/MGI:2182335#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-090313-249", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090313-249#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "cytosol", "id": "GO:0005829", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005829", "evidence": [ { "database": "UniProtKB", "id": "E7F0B6", "url": "https://www.uniprot.org/uniprotkb/E7F0B6" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "cell division", "id": "GO:0051301", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051301", "evidence": [ { "database": "UniProtKB", "id": "E7F0B6", "url": "https://www.uniprot.org/uniprotkb/E7F0B6" } ], "pmid": "" }, { "name": "regulation of cell cycle", "id": "GO:0051726", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0051726", "evidence": [ { "database": "UniProtKB", "id": "E7F0B6", "url": "https://www.uniprot.org/uniprotkb/E7F0B6" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 171, "end_pos": 173, "annotation": "n_glycosylation_sequon" }, { "start_pos": 305, "end_pos": 307, "annotation": "n_glycosylation_sequon" }, { "start_pos": 361, "end_pos": 363, "annotation": "n_glycosylation_sequon" }, { "start_pos": 42, "end_pos": 44, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F0B6", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0B6" }, { "id": "SM00385", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00385" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Cyclin-like", "eco_id": "ECO_0000259", "start_pos": 383, "end_pos": 470, "start_aa": "Arg", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 171, "end_pos": 173 }, { "start_pos": 305, "end_pos": 307 }, { "start_pos": 361, "end_pos": 363 }, { "start_pos": 42, "end_pos": 44 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F0J8-1", "uniprot_ac": "E7F0J8", "uniprot_id": "E7F0J8_DANRE", "mass": { "chemical_mass": 23052.0, "monoisotopic_mass": 23052.0 }, "refseq": { "ac": "NP_001373337", "name": "neuromast-expressed gpi-anchored lymphocyte antigen 6 precursor", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373337" }, "gene_names": [ { "name": "negaly6", "type": "recommended", "evidence": [ { "id": "E7F0J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0J8" } ] }, { "name": "negaly6", "type": "synonym", "evidence": [ { "id": "NP_001373337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373337" } ] }, { "name": "si:dkey-79d12.2", "type": "synonym", "evidence": [ { "id": "NP_001373337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373337" }, { "id": "E7F0J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0J8" } ] } ], "protein_names": [ { "name": "Neuromast-expressed gpi-anchored lymphocyte antigen 6 precursor", "type": "synonym", "evidence": [ { "id": "E7F0J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0J8/entry#names_and_taxonomy" } ] }, { "name": "neuromast-expressed gpi-anchored lymphocyte antigen 6 precursor", "type": "synonym", "evidence": [ { "id": "NP_001373337", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373337" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: CO924904.1, SRR32588729.16904429.1 [ECO:0000332] RNAseq introns :: mixed sample support SAMEA3505370, SAMEA3505371 [ECO:0006172] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000016.1. On Aug 21, 2020 this sequence version replaced XP_002664937.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001373337", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373337" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F0J8", "url": "https://www.uniprot.org/uniprotkb/E7F0J8" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "negaly6", "url": "https://www.uniprot.org/uniprotkb/E7F0J8", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-131121-604", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-131121-604", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "100334152", "url": "https://www.ncbi.nlm.nih.gov/gene/100334152", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR016054", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016054", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR045860", "url": "https://www.ebi.ac.uk/interpro/entry/IPR045860", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR050918", "url": "https://www.ebi.ac.uk/interpro/entry/IPR050918", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100334152", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100334152", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "E7F0J8", "url": "https://www.orthodb.org/?gene=E7F0J8", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR20914", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20914", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR20914:SF24", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR20914:SF24", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00021", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00021", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001373337", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001373337", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7F0J8", "url": "https://www.uniprot.org/uniprotkb/E7F0J8", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0J8-1", "url": "https://www.uniprot.org/uniprotkb/E7F0J8-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-131121-604", "url": "https://zfin.org/ZDB-GENE-131121-604", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAWSVLFIFTCTLFYKVSSLTCYQCIPETSIKCTETTVDCPVGQCGTMKTTSYLGNNAISDMIMKNCSATQECVTASVNFGVTKIIINNECCNTDLCNKQIKQESQNRIPNGMHCYTCKGEDCLSTLPCADGEDHCVKATVISEGQMMTMRGCATRSFCRGDLSSQISQNNTAAVGLTCCKGHLCNSSKTLIQSHMVQLSFLMCAIIHMLL", "length": 211, "header": "tr|E7F0J8-1|E7F0J8_DANRE Isoform 1 of Neuromast-expressed gpi-anchored lymphocyte antigen 6 precursor OS=Danio rerio OX=7955 GN=negaly6 PE=4 SV=1 CANONICAL=E7F0J8-1" }, "isoforms": [ { "isoform_ac": "E7F0J8-1", "url": "https://www.uniprot.org/uniprotkb/E7F0J8/entry#E7F0J8-1", "sequence": { "sequence": "MAWSVLFIFTCTLFYKVSSLTCYQCIPETSIKCTETTVDCPVGQCGTMKTTSYLGNNAISDMIMKNCSATQECVTASVNFGVTKIIINNECCNTDLCNKQIKQESQNRIPNGMHCYTCKGEDCLSTLPCADGEDHCVKATVISEGQMMTMRGCATRSFCRGDLSSQISQNNTAAVGLTCCKGHLCNSSKTLIQSHMVQLSFLMCAIIHMLL", "length": 211, "header": "tr|E7F0J8-1|E7F0J8_DANRE Isoform 1 of Neuromast-expressed gpi-anchored lymphocyte antigen 6 precursor OS=Danio rerio OX=7955 GN=negaly6 PE=4 SV=1 CANONICAL=E7F0J8-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "Identification of a Ly-6 superfamily gene expressed in lateral line neuromasts in zebrafish.", "journal": "Dev. Genes Evol.", "date": "2015", "authors": "Ji Dongrui, Li Lingyi, Zhang Shicui, Li Hongyan", "evidence": [ { "database": "UniProtKB", "id": "E7F0J8", "url": "https://www.uniprot.org/uniprotkb/E7F0J8" } ], "reference": [ { "type": "PubMed", "id": "25586305", "url": "https://glygen.org/publication/PubMed/25586305" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. 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"url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005576", "evidence": [ { "database": "UniProtKB", "id": "E7F0J8", "url": "https://www.uniprot.org/uniprotkb/E7F0J8" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 170, "end_pos": 172, "annotation": "n_glycosylation_sequon" }, { "start_pos": 186, "end_pos": 188, "annotation": "n_glycosylation_sequon" }, { "start_pos": 66, "end_pos": 68, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F0J8", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0J8" }, { "id": "SM00134", "database": "SMART", "url": "http://smart.embl.de/smart/do_annotation.pl?DOMAIN=SM00134" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "UPAR/Ly6", "eco_id": "ECO_0000259", "start_pos": 20, "end_pos": 112, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 170, "end_pos": 172 }, { "start_pos": 186, "end_pos": 188 }, { "start_pos": 66, "end_pos": 68 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", 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"field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F0K5-1", "uniprot_ac": "E7F0K5", "uniprot_id": "E7F0K5_DANRE", "mass": { "chemical_mass": 17595.0, "monoisotopic_mass": 17595.0 }, "refseq": { "ac": "XP_696547", "name": "MAP3K7 C-terminal-like protein isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696547" }, "gene_names": [ { "name": "map3k7cl", "type": "recommended", "evidence": [ { "id": "E7F0K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0K5" } ] }, { "name": "map3k7cl", "type": "synonym", "evidence": [ { "id": "XP_696547", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696547" } ] } ], "protein_names": [ { "name": "MAP3K7 C-terminal-like protein isoform X1", "type": "synonym", "evidence": [ { "id": "XP_696547", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696547" }, { "id": "E7F0K5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0K5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Mar 23, 2011 this sequence version replaced XP_696547.3. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_696547", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696547" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F0K5", "url": "https://www.uniprot.org/uniprotkb/E7F0K5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "map3k7cl", "url": "https://www.uniprot.org/uniprotkb/E7F0K5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091204-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-239", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000069143", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000069143", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "568142", "url": "https://www.ncbi.nlm.nih.gov/gene/568142", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR042800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "CKMANEF", "url": "https://omabrowser.org/oma/group/CKMANEF/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F0K5", "url": "https://www.orthodb.org/?gene=E7F0K5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR47140", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47140", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR47140:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR47140:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF27575", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF27575", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_696547", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_696547", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58GMC5", "url": "https://www.uniprot.org/uniprotkb/A0AC58GMC5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GMC5-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GMC5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GMC6", "url": "https://www.uniprot.org/uniprotkb/A0AC58GMC6", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GMC6-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GMC6-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0K5", "url": "https://www.uniprot.org/uniprotkb/E7F0K5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0K5-1", "url": "https://www.uniprot.org/uniprotkb/E7F0K5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091204-239", "url": "https://zfin.org/ZDB-GENE-091204-239", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MDVDVSAETLELRYQILSFSYQACYSACVFLSELKDAEDPLPSFPDLEQRLQPVLPCRSLKESIEVYKDHCKMANEFNQVKHEIARLEDRKKELMAELLEDEKASMEFARYEEEYRILTEENQNLITVHSERAQQLETLRVISQKRQGSS", "length": 150, "header": "tr|E7F0K5-1|E7F0K5_DANRE Isoform 1 of MAP3K7 C-terminal-like protein isoform X1 OS=Danio rerio OX=7955 GN=map3k7cl PE=4 SV=2 CANONICAL=E7F0K5-1" }, "isoforms": [ { "isoform_ac": "A0AC58GMC5-1", "url": "https://www.uniprot.org/uniprotkb/E7F0K5/entry#A0AC58GMC5-1", "sequence": { "sequence": "MANEFNQVKHEIARLEDRKKELMAELLEDEKASMEFARYEEEYRILTEENQNLITVHSERAQQLETLRVISQKRQGSS", "length": 78, "header": "tr|A0AC58GMC5-1|A0AC58GMC5_DANRE Computationally mapped isoform of MAP3K7 C-terminal-like protein isoform X3 OS=Danio rerio OX=7955 GN=map3k7cl PE=4 SV=1 CANONICAL=E7F0K5-1" }, "locus": {} }, { "isoform_ac": "A0AC58GMC6-1", "url": "https://www.uniprot.org/uniprotkb/E7F0K5/entry#A0AC58GMC6-1", "sequence": { "sequence": "MITSTRRVSADKPEVQIAFSLDETSELKDAEDPLPSFPDLEQRLQPVLPCRSLKESIEVYKDHCKMANEFNQVKHEIARLEDRKKELMAELLEDEKASMEFARYEEEYRILTEENQNLITVHSERAQQLETLRVISQKRQGSS", "length": 143, "header": "tr|A0AC58GMC6-1|A0AC58GMC6_DANRE Computationally mapped isoform of MAP3K7 C-terminal-like protein isoform X2 OS=Danio rerio OX=7955 GN=map3k7cl PE=4 SV=1 CANONICAL=E7F0K5-1" }, "locus": {} }, { "isoform_ac": "E7F0K5-1", "url": "https://www.uniprot.org/uniprotkb/E7F0K5/entry#E7F0K5-1", "sequence": { "sequence": "MDVDVSAETLELRYQILSFSYQACYSACVFLSELKDAEDPLPSFPDLEQRLQPVLPCRSLKESIEVYKDHCKMANEFNQVKHEIARLEDRKKELMAELLEDEKASMEFARYEEEYRILTEENQNLITVHSERAQQLETLRVISQKRQGSS", "length": 150, "header": "tr|E7F0K5-1|E7F0K5_DANRE Isoform 1 of MAP3K7 C-terminal-like protein isoform X1 OS=Danio rerio OX=7955 GN=map3k7cl PE=4 SV=2 CANONICAL=E7F0K5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "A0ABK0LTI0-1", "protein_name": "MAP3K7 C-terminal like", "gene_name": "Map3k7cl", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MELRSNPRSLEVQISSLCLVTSLKSTRKPLPGFTTLHSSRLPRKGLYATGRPQDMQVHDPRNDTPSEEATPLVFPELEQQLQPLPPCHDSAESMQVFKQHCQIAEEYHEVKKEIALLEERKKELIAKLDQAEKEKLDAAQLVREFEALTEENRTLKMAQSQCVEQLEKLRIQYQKRQGSS", "length": 180 }, "evidence": [ { "id": "MGI:2446584", "url": "https://alliancegenome.org/gene/MGI:2446584#orthology", "database": "AGR" }, { "id": "HGNC:16457", "url": "https://alliancegenome.org/gene/HGNC:16457#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "P57077-4", "protein_name": "MAP3K7 C-terminal-like protein", "gene_name": "MAP3K7CL", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MISTARVPADKPVRIAFSLNDASDDTPPEDSIPLVFPELDQQLQPLPPCHDSEESMEVFKQHCQIAEEYHEVKKEITLLEQRKKELIAKLDQAEKEKVDAAELVREFEALTEENRTLRLAQSQCVEQLEKLRIQYQKRQGSS", "length": 142 }, "evidence": [ { "id": "MGI:2446584", "url": "https://alliancegenome.org/gene/MGI:2446584#orthology", "database": "AGR" }, { "id": "HGNC:16457", "url": "https://alliancegenome.org/gene/HGNC:16457#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-239#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P58500-1", "protein_name": "MAP3K7 C-terminal-like protein", "gene_name": "Map3k7cl", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MISTARVPADKPVRIAFSLNDAPDDTPSEDAIPLVFPELEQQLQPLPPCHDSVESMQVFKQHCQIAEEYHEVKKEIALLEERKKELIAKLDQAEKEKLDAAQLVQEFEALTEENRTLKMAQSQCVEQLENLRIQYQKRQGSS", "length": 142 }, "evidence": [ { "id": "MGI:2446584", "url": "https://alliancegenome.org/gene/MGI:2446584#orthology", "database": "AGR" }, { "id": "HGNC:16457", "url": "https://alliancegenome.org/gene/HGNC:16457#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091204-239", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091204-239#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F0N5-1", "uniprot_ac": "E7F0N5", "uniprot_id": "E7F0N5_DANRE", "mass": { "chemical_mass": 84692.0, "monoisotopic_mass": 84692.0 }, "refseq": { "ac": "XP_009304438", "name": "NTPase KAP family P-loop domain-containing protein 1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304438" }, "gene_names": [ { "name": "nkpd1", "type": "recommended", "evidence": [ { "id": "E7F0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0N5" } ] }, { "name": "nkpd1", "type": "synonym", "evidence": [ { "id": "XP_009304438", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304438" } ] } ], "protein_names": [ { "name": "NTPase KAP family P-loop domain-containing protein 1", "type": "synonym", "evidence": [ { "id": "XP_009304438", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304438" }, { "id": "E7F0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0N5/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 24, 2016 this sequence version replaced XP_009304438.1. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009304438", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304438" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F0N5", "url": "https://www.uniprot.org/uniprotkb/E7F0N5" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "nkpd1", "url": "https://www.uniprot.org/uniprotkb/E7F0N5", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-141215-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141215-19", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000075698", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000075698", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "561946", "url": "https://www.ncbi.nlm.nih.gov/gene/561946", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR011646", "url": "https://www.ebi.ac.uk/interpro/entry/IPR011646", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR052754", "url": "https://www.ebi.ac.uk/interpro/entry/IPR052754", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR057092", "url": "https://www.ebi.ac.uk/interpro/entry/IPR057092", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561946", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561946", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "SEAKEMY", "url": "https://omabrowser.org/oma/group/SEAKEMY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F0N5", "url": "https://www.orthodb.org/?gene=E7F0N5", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR22674", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22674", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR22674:SF6", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR22674:SF6", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF07693", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07693", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "PF23307", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23307", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_009304438", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304438", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7F0N5", "url": "https://www.uniprot.org/uniprotkb/E7F0N5", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0N5-1", "url": "https://www.uniprot.org/uniprotkb/E7F0N5-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-141215-19", "url": "https://zfin.org/ZDB-GENE-141215-19", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MAIEKVTDIPSDNVYAYALSKTLTKVSSPVTVGLYSECHNRINMVLKNIEVHMNQEGKRREEKYTKEPKPRSVKPSISNLISVIFRLLFCRPVWTEQNQNMKNVRYIFVRFSAWHFAGSDLLWAGLVMQLSKALQHSFGKLQLALFRIAQYDEEEDAKKKMIEDIPKNWRSKKLGCIPIWALILMIIIASLLILVPLIIFGFSYLKGDQQNEESSSYGVIEGFAITALGVPAVGALRFIILLLKNLILNQDLKIRQGLDNKKVSEQLGLMHEVRKEMRLLCCFIFFMEIFERRRIRVVLEITNLDRCTPKKIVGVLDAINILLSDDESPFISVLAVDPEVLVRQVQQAEDCLRKRNTAYDFLDRIITLPFTVPPLSDSSKSSVFENIVRGQSEIPEEIPLETGASTFKGPGTSFSVEDEYSVRFDETKEEQEIPLIGKKANNETFAVAELNLEDVDRFIESAFTFIFSRDTSKLNKYLSGDTMSMRRVINSIRVTIMIMEIRKLEPPHPEKIAAWIVLLDRWPCRVSWILQCVEDDQQSYEIDDSSCAADATKTIWEVFNYNSLELCMIEHAVENFLERDGDPELFEIFLRKDFKFTVRELEMFKLCTVNLNYSIKKELARVRGRRRLRRAGRNAFQSISSRTLMNMNPEDICQEMTKLSLPEKYLETVRTNFIDGRTILFGDPKDLRQVLQMTLGEWMTFKFHFLGVTPSSRPAQPQSHLAATNPGVVICPSGHGR", "length": 737, "header": "tr|E7F0N5-1|E7F0N5_DANRE Isoform 1 of NTPase KAP family P-loop domain-containing protein 1 OS=Danio rerio OX=7955 GN=nkpd1 PE=4 SV=1 CANONICAL=E7F0N5-1" }, "isoforms": [ { "isoform_ac": "E7F0N5-1", "url": "https://www.uniprot.org/uniprotkb/E7F0N5/entry#E7F0N5-1", "sequence": { "sequence": "MAIEKVTDIPSDNVYAYALSKTLTKVSSPVTVGLYSECHNRINMVLKNIEVHMNQEGKRREEKYTKEPKPRSVKPSISNLISVIFRLLFCRPVWTEQNQNMKNVRYIFVRFSAWHFAGSDLLWAGLVMQLSKALQHSFGKLQLALFRIAQYDEEEDAKKKMIEDIPKNWRSKKLGCIPIWALILMIIIASLLILVPLIIFGFSYLKGDQQNEESSSYGVIEGFAITALGVPAVGALRFIILLLKNLILNQDLKIRQGLDNKKVSEQLGLMHEVRKEMRLLCCFIFFMEIFERRRIRVVLEITNLDRCTPKKIVGVLDAINILLSDDESPFISVLAVDPEVLVRQVQQAEDCLRKRNTAYDFLDRIITLPFTVPPLSDSSKSSVFENIVRGQSEIPEEIPLETGASTFKGPGTSFSVEDEYSVRFDETKEEQEIPLIGKKANNETFAVAELNLEDVDRFIESAFTFIFSRDTSKLNKYLSGDTMSMRRVINSIRVTIMIMEIRKLEPPHPEKIAAWIVLLDRWPCRVSWILQCVEDDQQSYEIDDSSCAADATKTIWEVFNYNSLELCMIEHAVENFLERDGDPELFEIFLRKDFKFTVRELEMFKLCTVNLNYSIKKELARVRGRRRLRRAGRNAFQSISSRTLMNMNPEDICQEMTKLSLPEKYLETVRTNFIDGRTILFGDPKDLRQVLQMTLGEWMTFKFHFLGVTPSSRPAQPQSHLAATNPGVVICPSGHGR", "length": 737, "header": "tr|E7F0N5-1|E7F0N5_DANRE Isoform 1 of NTPase KAP family P-loop domain-containing protein 1 OS=Danio rerio OX=7955 GN=nkpd1 PE=4 SV=1 CANONICAL=E7F0N5-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561946", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561946", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "D3ZR21-1", "protein_name": "NTPase, KAP family P-loop domain containing 1", "gene_name": "Nkpd1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQKNYNVHFTKNARAPNEQHFLDPELGHQKGCCRQCYQDLVATHTHGPYQLSPQAHWQQTYRSHRGGSGCRRCPQPLILQRQRQQQKRQPPSFPPSPQRQRLCPVRGAQKGSPAIAAARMGPASAPQPATSSPTAVPPTASSGPALPSAAGALLEPSEPTEARPLPAPAACGSFTSYGADILTEDDVYCSCLAKTLCHVPVPVTVGFYAPFGCRLHLMLDKIMTLMQQEAAQRESEELQRVQWQPRPVRGWGVPQLLWFLVFLQPVITELHLRRRNVRFLFIRFSAWQYAGTDKLWAGLVTTLCEGIRHHYGALPFSVYSVLGNKPCGPRDGLCQREWHCRRRVCLALLALLAALCLGVGLLYLSLGGHAPGHAERGVLKALGGAATTLSGSGLLMAVYSVGKHLFVSQRKKIERLVSREKFGSQLGFMCEVKKEVELLTDFLCFLEIYQRRRLRVVLEVTGLDTCYPERVVGVLNAINTLLSDSHAPFIFILVVDPSILAACLESAGNMKGTADNGYLFLNRTVTLPFSVPVMGRRTKLQFLHDAVRSRDDLLFRELTIKLQPQSPGVLGAGEGTQLLAVETQADTERTQGRVDAEAARRIQEALCCLHDEGDCLYEYVPDNVVSMRRIVNTVPITVRLLQQQQHQQPDRVGPTPRHAVAWVVLANQWPCRLSWVLQCLEDRQQAGGAPEGRARLWDVFCDNSRELHTMTKALQNVLDLDGDPELFERFLGTDFPFTVADAQSLLRCTVNLDHSIRRRMGLIRAVSALKPPSPPKSPSRDGPQAGPRATIAAGTSQAGQGSGHSREAHQTRDRTHGVKPRPMA", "length": 824 }, "evidence": [ { "id": "RGD:1591760", "url": "https://alliancegenome.org/gene/RGD:1591760#orthology", "database": "AGR" }, { "id": "MGI:1916797", "url": "https://alliancegenome.org/gene/MGI:1916797#orthology", "database": "AGR" }, { "id": "HGNC:24739", "url": "https://alliancegenome.org/gene/HGNC:24739#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141215-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141215-19#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q0VF94-1", "protein_name": "NTPase KAP family P-loop domain-containing protein 1", "gene_name": "Nkpd1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQQEAAQRESEELQRVQWQPRRVRGWGVPKLLWFLVFLQPVITELHLRRRNVRFLFIRFSAWQYAGTDKLWAGLVTTLCEGIRHHYGALPFSVYSVLGNKPCGPRDGLCQREWHCRRRVCLALLALLAALCLGVGLLYLSLGGHAPGHGERGVLKALGGAATTLSGSGLLMAVYSVGKHLFVSQRKKIERLVSREKFGSQLGFMCEVKKEVELLTDFLCFLEIYQRRRLRVVLEVTGLDTCYPERVVGVLNAINTLLSDSHAPFIFILVVDPSILAACLESAGNMKGTADNGYLFLNRTVTLPFSVPIMGRRTKLQFLHDAVRSRDDLLFRELTIKLQPQSPGNLGAGEGTQLLAVETQGDAERTQGRVDAEAARRIQEALCCLHDEGDCLYEYVPDNVVSMRRIVNTVPITVRLLQQQQQQQPDRVGPTPRHAVAWVVLANQWPCRLSWVLQCLEDRQQAGGAPEGRSRLWDVFCDNSRELHTMTKALQNVLDLDGDPELFERFLGTDFPFTVAEAQSLLRCTVNLDHSIRRRMGLIRAVSALKPPSPPKSPSQDGPQASPRAIIAAGTSHAGQGSGHSKEAHQTRDRTHGGKPRPMA", "length": 599 }, "evidence": [ { "id": "RGD:1591760", "url": "https://alliancegenome.org/gene/RGD:1591760#orthology", "database": "AGR" }, { "id": "MGI:1916797", "url": "https://alliancegenome.org/gene/MGI:1916797#orthology", "database": "AGR" }, { "id": "HGNC:24739", "url": "https://alliancegenome.org/gene/HGNC:24739#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141215-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141215-19#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q17RQ9-1", "protein_name": "NTPase KAP family P-loop domain-containing protein 1", "gene_name": "NKPD1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQEAAQRESEELQHVQWRPRAVSGWGVPQLLWYLVFLQPIITEVHLRRRNVQFLFIRFSAWQYAGTDKLWAGLVTTLCEGIRRHYGALPFSVYSVLGNKPATRQDCCQSEWHCRRRVCLGLLALLAALGLGVGLLYLSLGGHALGHGSPSGSLLKVFGGAATTLSGSGLLMAVYSVGKHLFVSQRKKIERLVSREKFGSQLGFMCEVKKEVELLTDFLCFLEIYQRRRLRVVLEVTGLDTCYPERVVGVLNAINTLLSDSHAPFIFILVVDPSILAACLESAGNMKGTADNGYLFLNRTVTLPFSVPIMGRRTKLQFLHDAVQSRDDLLYREMTRKPWLPGDAGGESAQLLAVQAQAGTERGQGRIDDEAARRIQEALFCLHDERDCLYEYVPDNVVSMRRIVNTVPITVRLLQQQQQQGDFGGPTPRQAVAWVVLANQWPCRLSWALQCLEDRQQTGGAPEGRARLWDVFRDNSRELHTMTKALQNVLDLDGDPELFERFLGADFPFTVAEAQSLLRCTVNLDHSIRRRMGLIRAVSALKPPSPPKSPTRDTPHAAHRANSASRAPPSGRASGQAGEGHHTGDLAHRGKLWPVACALFRPGQSSPGGP", "length": 610 }, "evidence": [ { "id": "RGD:1591760", "url": "https://alliancegenome.org/gene/RGD:1591760#orthology", "database": "AGR" }, { "id": "MGI:1916797", "url": "https://alliancegenome.org/gene/MGI:1916797#orthology", "database": "AGR" }, { "id": "HGNC:24739", "url": "https://alliancegenome.org/gene/HGNC:24739#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-141215-19", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-141215-19#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 442, "end_pos": 444, "annotation": "n_glycosylation_sequon" }, { "start_pos": 612, "end_pos": 614, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0N5" }, { "id": "PF07693", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF07693" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "KAP NTPase", "eco_id": "ECO_0000259", "start_pos": 46, "end_pos": 437, "start_aa": "Leu", "end_aa": "Gly", "glycosite_overlap": "" }, { "evidence": [ { "id": "E7F0N5", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0N5" }, { "id": "PF23307", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF23307" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Kinase D-interacting substrate of 220 kDa-like SAM", "eco_id": "ECO_0000259", "start_pos": 643, "end_pos": 704, "start_aa": "Thr", "end_aa": "His", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 442, "end_pos": 444 }, { "start_pos": 612, "end_pos": 614 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", 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{ "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F0N7-1", "uniprot_ac": "E7F0N7", "uniprot_id": "E7F0N7_DANRE", "mass": { "chemical_mass": 11977.0, "monoisotopic_mass": 11977.0 }, "refseq": { "ac": "XP_021336965", "name": "SH2 domain-containing protein 1A", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336965" }, "gene_names": [ { "name": "sh2d1ab", "type": "recommended", "evidence": [ { "id": "E7F0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0N7" } ] }, { "name": "sh2d1ab", "type": "synonym", "evidence": [ { "id": "XP_021336965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336965" } ] } ], "protein_names": [ { "name": "SH2 domain-containing protein 1A", "type": "synonym", "evidence": [ { "id": "XP_021336965", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336965" }, { "id": "E7F0N7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0N7/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_021336965", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_021336965" } ] } ], "disease": [ { "disease_id": "DOID:0060705", "recommended_name": { "id": "DOID:0060705", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060705", "name": "X-linked lymphoproliferative syndrome 1", "description": "A lymphoproliferative syndrome characterized by severe immune dysregulation after viral infection that may manifest as severe or fatal mononucleosis, acquired hypogammaglobulinema, hemophagocytic lymphohistiocytosis, and/or malignant lymphoma and that has_material_basis_in X-linked mutation in the SH2D1A gene on chromosome Xq25." }, "synonyms": [ { "id": "DOID:0060705", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0060705", "name": "XLP1", "description": "" }, { "id": "MONDO:0024551", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024551", "name": "X-linked lymphoproliferative disease due to SH2D1A deficiency", "description": "A rare, genetic, primary immunodeficiency disorder characterized by an abnormal immune response to Epstein-Barr virus (EBV) infection, caused by hemizygous mutations in the X-linked SH2D1A gene, resulting in B cell lymphoproliferation and manifesting with various phenotypes which include EBV-driven severe or fulminant mononucleosis, hemophagocytic lymphohistiocytosis (presenting with fulminant hepatitis, hepatic necrosis, bone marrow hypoplasia, and neurological involvement), hypogammaglobulinemia, and B-cell lymphoma. Additional variable manifestations include vasculitis, lymphomatoid granulomatosis, aplastic anemia, and chronic gastritis. Occasionally, T-cell lymphoma may be observed. Laboratory findings include normal or increased activated T cells and reduced memory B cells." }, { "id": "MONDO:0024551", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024551", "name": "X-linked lymphoproliferative disease due to SH2D1A deficiency", "description": "" }, { "id": "MONDO:0024551", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024551", "name": "lymphoproliferative syndrome, X-linked, 1, X-linked recessive", "description": "" }, { "id": "MONDO:0024551", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0024551", "name": "XLP1", "description": "" }, { "id": "MIM:308240", "resource": "MIM", "url": "https://www.omim.org/entry/308240", "name": "Lymphoproliferative syndrome, X-linked, 1", "description": "Lymphoproliferative syndrome, X-linked, 1" } ], "unlinked_id_list": [], "evidence": [ { "id": "0060705", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:0060705" } ] } ], 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"UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0N7" }, { "id": "PS50001", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50001" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "SH2", "eco_id": "ECO_0000259", "start_pos": 6, "end_pos": 102, "start_aa": "Val", "end_aa": "Val", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": 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"o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F0Q1-1", "uniprot_ac": "E7F0Q1", "uniprot_id": "E7F0Q1_DANRE", "mass": { "chemical_mass": 78201.0, "monoisotopic_mass": 78201.0 }, "refseq": { "ac": "XP_017213507", "name": "MAM domain-containing protein 2 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213507" }, "gene_names": [ { "name": "mamdc2b", "type": "recommended", "evidence": [ { "id": "E7F0Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0Q1" } ] }, { "name": "mamdc2b", "type": "synonym", "evidence": [ { "id": "XP_017213507", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213507" } ] } ], "protein_names": [ { "name": "MAM domain-containing protein 2 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_017213507", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213507" }, { "id": "E7F0Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0Q1/entry#names_and_taxonomy" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133185) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_017213507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213507" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F0Q1", "url": "https://www.uniprot.org/uniprotkb/E7F0Q1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "mamdc2b", "url": "https://www.uniprot.org/uniprotkb/E7F0Q1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-091117-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091117-16", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000073695", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000073695", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd06263", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd06263", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "798369", "url": "https://www.ncbi.nlm.nih.gov/gene/798369", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR000998", "url": "https://www.ebi.ac.uk/interpro/entry/IPR000998", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR013320", "url": "https://www.ebi.ac.uk/interpro/entry/IPR013320", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR051560", "url": "https://www.ebi.ac.uk/interpro/entry/IPR051560", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:798369", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798369", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "STCKSFW", "url": "https://omabrowser.org/oma/group/STCKSFW/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F0Q1", "url": "https://www.orthodb.org/?gene=E7F0Q1", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23282", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23282", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23282:SF101", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23282:SF101", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00629", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00629", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_017213507", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_017213507", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58GLL2", "url": "https://www.uniprot.org/uniprotkb/A0AC58GLL2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GLL2-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GLL2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GLN0", "url": "https://www.uniprot.org/uniprotkb/A0AC58GLN0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GLN0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GLN0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0Q1", "url": "https://www.uniprot.org/uniprotkb/E7F0Q1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0Q1-1", "url": "https://www.uniprot.org/uniprotkb/E7F0Q1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-091117-16", "url": "https://zfin.org/ZDB-GENE-091117-16", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MLKQVLFYLHLAGLNTGGKMLSFCLLSLIVTTQAELLPGSCSFQESICDYMSDPSFLSWTLNPSGHFITVEEQVQEDQRKAVLLGPDVDQQDWSCFRMVYQVTGGASLQVQRRTDGESFDRVLWSTQSSSDSWRIASIDLHNSNEAFKIVIEGRLGAEEGSSVSIFEIRISDRYCIECDFEEAHLCGYANQWNKYLNWRVGKSENNTLNDKAGQFMYVDSTDSKGFQEVAKLVSPMTTAPLSGCLSFQYQQYQAGDHLFSLFSRDQAGQYEELWRADQKENNFADWSPEDKVWIPVQVDLKAPYPVELVFEVGFNGPHGGFVVLDDISFSSEFCDGRTEPSFDPAVANCDFESGFCQYVQSDGSLWRRVSVKPNIYMTGDHTTGAGSFLLANSRLSLQSGYVSRLFGPSMPGSQKYCLKFFYSLRGLSGADQALSVYLYYSDSSKHEQMWTQNEKIRNVWIAVELTIQSEKKAQVVFISTCKDIWSCGSVGLDDIKVTPGDCSLLAASSLLLPSHCDFESGLCGFSQDKVGDSGDWYLARGPTPTSYTGPGGDHTTGLGHYMHIEASVMLAGHKARLLSSTLRGTRETQCLQFYYHMYGSGIGQLSVYLQTGQENDDRLLWTSHGEQGISWLRASLNYHYDQQHQIVFEATRGASVRSDIAVDDIIFERGPCREYSDQHIPHLSLSGNNNDIQTMHFK", "length": 698, "header": "tr|E7F0Q1-1|E7F0Q1_DANRE Isoform 1 of MAM domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=mamdc2b PE=4 SV=1 CANONICAL=E7F0Q1-1" }, "isoforms": [ { "isoform_ac": "A0AC58GLL2-1", "url": "https://www.uniprot.org/uniprotkb/E7F0Q1/entry#A0AC58GLL2-1", "sequence": { "sequence": "MLKQVLFYLHLAGLNTGGKMLSFCLLSLIVTTQAELLPGSCSFQESICDYMSDPSFLSWTLNPSGHFITVEEQVQEDQRKAVLLGPDVDQQDWSCFRMVYQVTGGASLQVQRRTDGESFDRVLWSTQSSSDSWRIASIDLHNSNEAFKIVIEGRLGAEEGSSVSIFEIRISDRYCIECDFEEAHLCGYANQWNKYLNWRVGKSENNTLNDKAGQFMYVDSTDSKGFQEVAKLVSPMTTAPLSGCLSFQYQQYQAGDHLFSLFSRDQAGQYEELWRADQKENNFADWSPEDKVWIPVQVDLKAPYPVELVFEVGFNGPHGGFVVLDDISFSSEFCDGRTEPSFDPAVANCDFESGFCQYVQSDGSLWRRVSVKPNIYMTGDHTTGAGSFLLANSRLSLQSGYVSRLFGPSMPGSQKYCLKFFYSLRGLSGADQALSVYLYYSDSSKHEQMWTQNEKIRNVWIAVELTIQSEKKAQVVFISTCKDIWSCGSVGLDDIKVTPGDCSLLASSLLLPSHCDFESGLCGFSQDKVGDSGDWYLARGPTPTSYTGPGGDHTTGLGHYMHIEASVMLAGHKARLLSSTLRGTRETQCLQFYYHMYGSGIGQLSVYLQTGQENDDRLLWTSHGEQGISWLRASLNYHYDQQHQIVFEATRGASVRSDIAVDDIIFERGPCREYSDQHIPHLSLSGNNNDIQTMHFK", "length": 697, "header": "tr|A0AC58GLL2-1|A0AC58GLL2_DANRE Computationally mapped isoform of MAM domain-containing protein 2 isoform X2 OS=Danio rerio OX=7955 GN=mamdc2b PE=4 SV=1 CANONICAL=E7F0Q1-1" }, "locus": {} }, { "isoform_ac": "A0AC58GLN0-1", "url": "https://www.uniprot.org/uniprotkb/E7F0Q1/entry#A0AC58GLN0-1", "sequence": { "sequence": "MYVDSTDSKGFQEVAKLVSPMTTAPLSGCLSFQYQQYQAGDHLFSLFSRDQAGQYEELWRADQKENNFADWSPEDKVWIPVQVDLKAPYPVELVFEVGFNGPHGGFVVLDDISFSSEFCDGRTEPSFDPAVANCDFESGFCQYVQSDGSLWRRVSVKPNIYMTGDHTTGAGSFLLANSRLSLQSGYVSRLFGPSMPGSQKYCLKFFYSLRGLSGADQALSVYLYYSDSSKHEQMWTQNEKIRNVWIAVELTIQSEKKAQVVFISTCKDIWSCGSVGLDDIKVTPGDCSLLAASSLLLPSHCDFESGLCGFSQDKVGDSGDWYLARGPTPTSYTGPGGDHTTGLGHYMHIEASVMLAGHKARLLSSTLRGTRETQCLQFYYHMYGSGIGQLSVYLQTGQENDDRLLWTSHGEQGISWLRASLNYHYDQQHQIVFEATRGASVRSDIAVDDIIFERGPCREYSDQHIPHLSLSGNNNDIQTMHFK", "length": 483, "header": "tr|A0AC58GLN0-1|A0AC58GLN0_DANRE Computationally mapped isoform of MAM domain-containing protein 2 isoform X3 OS=Danio rerio OX=7955 GN=mamdc2b PE=4 SV=1 CANONICAL=E7F0Q1-1" }, "locus": {} }, { "isoform_ac": "E7F0Q1-1", "url": "https://www.uniprot.org/uniprotkb/E7F0Q1/entry#E7F0Q1-1", "sequence": { "sequence": "MLKQVLFYLHLAGLNTGGKMLSFCLLSLIVTTQAELLPGSCSFQESICDYMSDPSFLSWTLNPSGHFITVEEQVQEDQRKAVLLGPDVDQQDWSCFRMVYQVTGGASLQVQRRTDGESFDRVLWSTQSSSDSWRIASIDLHNSNEAFKIVIEGRLGAEEGSSVSIFEIRISDRYCIECDFEEAHLCGYANQWNKYLNWRVGKSENNTLNDKAGQFMYVDSTDSKGFQEVAKLVSPMTTAPLSGCLSFQYQQYQAGDHLFSLFSRDQAGQYEELWRADQKENNFADWSPEDKVWIPVQVDLKAPYPVELVFEVGFNGPHGGFVVLDDISFSSEFCDGRTEPSFDPAVANCDFESGFCQYVQSDGSLWRRVSVKPNIYMTGDHTTGAGSFLLANSRLSLQSGYVSRLFGPSMPGSQKYCLKFFYSLRGLSGADQALSVYLYYSDSSKHEQMWTQNEKIRNVWIAVELTIQSEKKAQVVFISTCKDIWSCGSVGLDDIKVTPGDCSLLAASSLLLPSHCDFESGLCGFSQDKVGDSGDWYLARGPTPTSYTGPGGDHTTGLGHYMHIEASVMLAGHKARLLSSTLRGTRETQCLQFYYHMYGSGIGQLSVYLQTGQENDDRLLWTSHGEQGISWLRASLNYHYDQQHQIVFEATRGASVRSDIAVDDIIFERGPCREYSDQHIPHLSLSGNNNDIQTMHFK", "length": 698, "header": "tr|E7F0Q1-1|E7F0Q1_DANRE Isoform 1 of MAM domain-containing protein 2 isoform X1 OS=Danio rerio OX=7955 GN=mamdc2b PE=4 SV=1 CANONICAL=E7F0Q1-1" }, "locus": {} } ], "glycosylation": [ { "glytoucan_ac": "", "type": "O-linked", "subtype": "", "prediction_tool_list": [ { "label": "isoglyp", "url": "https://github.com/jonmohl/ISOGlyP" } ], "site_category": "predicted", "site_category_dict": { "predicted": true }, "site_seq": "", "relation": "attached", "comment": "", "icn3d_view": {}, "start_pos": 543, "start_aa": "Thr", "end_pos": 543, "end_aa": "Thr", "residue": "Thr", "site_lbl": "Thr543", "evidence": [ { "id": "", "database": "GlyGen", "url": "https://data.glygen.org/" } ] } ], "phosphorylation": [], "glycation": [], "keywords": [ "glycoprotein", "glycoprotein_predicted" ], "publication": [], "pathway": [ { "id": "dre:798369", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:798369", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0R4ITP4-1", "protein_name": "MAM domain-containing protein 2a precursor", "gene_name": "mamdc2a", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MSFLHPLTFLAVALVARSQTQLLRGSCTFEADSCGYTSDPAYAAWTINDEGRFITAESLSFGEKEKHVLVSPELELRDWSCVRLVYQISGSGSLQLHLRSEEENFDYMLWSAEKPSDSWLIASVDLRNISGTYQLLFEAKPSRGMGNSVAVFEIHIIPGYCIECNFEEHHLCGYSNQWNPNVNWYVGGSLVRDPRSNLPDDHTMNNGRGHYMYVDSVYAKRFQEVAKLVSPMTTTPMTGCLSFYYQRDQAIGNFFSVFTKDQLGHYEEIWRPDVYATSSWKLVQVDIKATHPLEVVFEVAFNSARGGHVALDDISFSSAFCHTETEPEIDPSVANCDFEEGLCQYYQEQTGGSLWNKVSVKPNVYRIGDHTTGTGSFLLTNTRHASRPGYVGRLFGPFLPGNHKYCLRFYYALHGFMKIDNALALYVYDENNIAQEKLWTVSERSRDVWTEVEVTYLKPMSTKVAFVSICRNFWDCGLVSLDDISVTLGDCRVNAGPLNPPPGHCNFETGDCGYTQKKKAKKGHWLRIRGQTPTSYTGPKGDHTLGVGYFMYIEASHMLPKQSAQLMSTELRGSSIPQCLIFFYHMYGSGTGTLSILLRKGDKERLLWSRQGEQSVSWMKAMVDYECYTRHWVIFEATRGSSIRSDIAIDDVVFKKGPCKDPGDSVSYSGFSENFNEIEY", "length": 680 }, "evidence": [ { "id": "MGI:1918988", "url": "https://alliancegenome.org/gene/MGI:1918988#orthology", "database": "AGR" }, { "id": "HGNC:23673", "url": "https://alliancegenome.org/gene/HGNC:23673#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "F1M9P7-1", "protein_name": "MAM domain-containing protein 2", "gene_name": "Mamdc2", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLLVGVLLVVQALLLANALDLPAGSCAFEEGTCGFDSVFAFLPWILNEEGHYVYVDTSFAKQGEKAVLLSSDLQAEEWNCLRLVYQITTPLGSVSEPSQLNLYVRFEDESFDRLLWSTKEPSDSWLIASLDLQNSSKKFKILIEGVLGQGNTASIALFEIKMTTGYCIDCDFEENHLCGFVNRWNPNVNWFVGGGTAKNTHSILPWDHTFRSEQGHYMYVDSVYVKHFQEVAQLISPMTTAPMSGCLSFYYQLQQGNDNVFSLYTRDMAGLYEEIWKVDSPGNAVWNLAEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISFSPVHCQNQTGLPFSAVGTSCDFEKDLCNFYQDKEGPGWTRVRVKANMYRTGDHTTGTGHYLLANTKFTSQPGYIGRLYGPSLPGNMQYCVRFHYAIIGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEVSFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGNCRSPERLPPPPGECTFDQDECAFTQEKRNRSSWHRGRGETPTSYTGPKGDHTTGVGYYMYIEASHMVYGQKAHLLSQPLRGVPGKHCLIFFYHMYGAGTGLLSVYLKREEDSKESLLWRRKGEQSISWLRALVEYSSRRQHQIIFEAIRGVSIRSDIAIDDVKFQAGPCEEMEDTSQQSSGYSEDLNEIDY", "length": 686 }, "evidence": [ { "id": "MGI:1918988", "url": "https://alliancegenome.org/gene/MGI:1918988#orthology", "database": "AGR" }, { "id": "HGNC:23673", "url": "https://alliancegenome.org/gene/HGNC:23673#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q7Z304-1", "protein_name": "MAM domain-containing protein 2", "gene_name": "MAMDC2", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MLLRGVLLALQALQLAGALDLPAGSCAFEESTCGFDSVLASLPWILNEEGHYIYVDTSFGKQGEKAVLLSPDLQAEEWSCLRLVYQITTSSESLSDPSQLNLYMRFEDESFDRLLWSAKEPSDSWLIASLDLQNSSKKFKILIEGVLGQGNTASIALFEIKMTTGYCIECDFEENHLCGFVNRWNPNVNWFVGGGSIRNVHSILPQDHTFKSELGHYMYVDSVYVKHFQEVAQLISPLTTAPMAGCLSFYYQIQQGNDNVFSLYTRDVAGLYEEIWKADRPGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISFSPVHCQNQTELLFSAVEASCNFEQDLCNFYQDKEGPGWTRVKVKPNMYRAGDHTTGLGYYLLANTKFTSQPGYIGRLYGPSLPGNLQYCLRFHYAIYGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEITFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGSCSSSEKLPPPPGECTFEQDECTFTQEKRNRSSWHRRRGETPTSYTGPKGDHTTGVGYYMYIEASHMVYGQKARLLSRPLRGVSGKHCLTFFYHMYGGGTGLLSVYLKKEEDSEESLLWRRRGEQSISWLRALIEYSCERQHQIIFEAIRGVSIRSDIAIDDVKFQAGPCGEMEDTTQQSSGYSEDLNEIEY", "length": 686 }, "evidence": [ { "id": "MGI:1918988", "url": "https://alliancegenome.org/gene/MGI:1918988#orthology", "database": "AGR" }, { "id": "HGNC:23673", "url": "https://alliancegenome.org/gene/HGNC:23673#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091117-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091117-16#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8CG85-1", "protein_name": "MAM domain-containing protein 2", "gene_name": "Mamdc2", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLLEGVLLVVQALQLASALDLPAGSCAFEEDTCGFDSVFAFLPWILNEEGHYVYMDTSFARQGEKAVLLSSDLQAEEWNCLRLVYQITTPPGSVSDPSQLNLYVRFEDESFDRLLWSTKEPSDSWLIASLDLQNTSKKFKILIEGVLGQGNTASIALFEIKMTAGYCIECDFEENHLCGFVNRWNPNVNWFVGGGTAKNTHSVLPQDHTFRSEHGHYMYVDSVYVKHFQEVAQLISPVTTASMSGCLSFYYQLQQGNDNVFSVYTRDMAGLYEEIWKVDSPGNAAWNLAEVEFSAPYPMEVIFEVAFNGPKGGYVALDDISFSPVHCQNQTGLPFSAVETSCDFEIGLCNFYQDKEGPGWTRVRVKANMYRAGDHTTGTGHYLLANTKFTSQPGYIGRLYGPSLPGNMQYCVRFHYAIFGFLKMSDTLAVYIFEENHVVQEKIWSVLESPRGVWMQAEISFKKPMPTKVVFMSLCKSFWDCGLVALDDITIQLGNCRSPARLPPPPGECTFDQDECAFTQEKRNRSSWHRGRGETPTSYTGPKGDHTTGVGYYMYIEASHMVYGQKAHLLSQPLRGVPGKHCLTFFYHMYGAGTGLLSVYLKREEDSEESLLWRRRGEQSISWLRALVEYSCRRRHQIIFEATRGVSIRSDIAIDDVKLQAGPCAGMEDTTEQSSGYSEDLNEIEY", "length": 686 }, "evidence": [ { "id": "MGI:1918988", "url": "https://alliancegenome.org/gene/MGI:1918988#orthology", "database": "AGR" }, { "id": "HGNC:23673", "url": "https://alliancegenome.org/gene/HGNC:23673#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-091117-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-091117-16#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7F0Q1", "url": "https://www.uniprot.org/uniprotkb/E7F0Q1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 205, "end_pos": 207, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F0Q1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0Q1" }, { "id": "PS50060", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50060" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "MAM", "eco_id": "ECO_0000259", "start_pos": 39, "end_pos": 177, "start_aa": "Gly", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [ 543 ], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 205, "end_pos": 207 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": 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"field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 1 }, { "field": "total_sites", "count": 1 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 1 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "exact_sites", "count": 1 }, { "field": "exact_o_linked_sites", "count": 1 }, { "field": "fuzzy_sites", "count": 0 } ], "sort_fields": [ "glytoucan_ac", "type", "subtype", "site_category", "site_seq", "relation", "comment", "start_pos", "start_aa", "end_pos", "end_aa", "residue", "site_lbl" ] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F0Y1-1", "uniprot_ac": "E7F0Y1", "uniprot_id": "E7F0Y1_DANRE", "mass": { "chemical_mass": 22370.0, "monoisotopic_mass": 22370.0 }, "refseq": { "ac": "XP_003200569", "name": "tetranectin", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200569" }, "gene_names": [ { "name": "clec3bb", "type": "recommended", "evidence": [ { "id": "E7F0Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0Y1" } ] }, { "name": "clec3bb", "type": "synonym", "evidence": [ { "id": "XP_003200569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200569" } ] } ], "protein_names": [ { "name": "Tetranectin", "type": "synonym", "evidence": [ { "id": "E7F0Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0Y1/entry#names_and_taxonomy" } ] }, { "name": "tetranectin", "type": "synonym", "evidence": [ { "id": "XP_003200569", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200569" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133194) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003200569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200569" } ] } ], "disease": [ { "disease_id": "DOID:0070441", "recommended_name": { "id": "DOID:0070441", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070441", "name": "retinal macular dystrophy 4", "description": "A retinal macular dystrophy characterized by late-onset macular degeneration, with multiple drusen-like deposits, macular geographic atrophy, and choroidal neovascularization that has_material_basis_in heterozygous mutation in the CLEC3B gene on chromosome 3p21." }, "synonyms": [ { "id": "DOID:0070441", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:0070441", "name": "MCDR4", "description": "" }, { "id": "MONDO:0859568", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0859568", "name": "macular 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"Juvenile osteochondrosis of Scheurermann", "description": "" }, { "id": "DOID:13300", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13300", "name": "Juvenile osteochondrosis of spine", "description": "" }, { "id": "DOID:13300", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13300", "name": "Scheuermann's kyphosis", "description": "" }, { "id": "DOID:13300", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:13300", "name": "Sherman's Disease", "description": "" }, { "id": "MONDO:0008410", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008410", "name": "Scheuermann disease", "description": "A disorder characterized by osteochondrosis of the vertebral epiphyses in childhood." }, { "id": "MONDO:0008410", "resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008410", "name": "Calve's disease", "description": "" }, { "id": "MONDO:0008410", "resource": 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"resource": "MONDO", "url": "https://monarchinitiative.org/disease/MONDO:0008410", "name": "juvenile kyphosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "13300", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:13300" } ] }, { "disease_id": "DOID:8398", "recommended_name": { "id": "DOID:8398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8398", "name": "osteoarthritis", "description": "An arthritis that has_material_basis_in worn out cartilage located_in joint." }, "synonyms": [ { "id": "DOID:8398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8398", "name": "Osteoarthrosis and allied disorder", "description": "" }, { "id": "DOID:8398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8398", "name": "degenerative arthritis", "description": "" }, { "id": "DOID:8398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8398", "name": "degenerative joint disease", "description": "" }, { "id": "DOID:8398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8398", "name": "hypertrophic arthritis", "description": "" }, { "id": "DOID:8398", "resource": "Disease Ontology", "url": "https://disease-ontology.org/term/DOID:8398", "name": "osteoarthrosis", "description": "" } ], "unlinked_id_list": [], "evidence": [ { "id": "8398", "database": "AGR", "url": "https://www.alliancegenome.org/disease/DOID:8398" } ] } ], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F0Y1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y1" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "clec3bb", "url": "https://www.uniprot.org/uniprotkb/E7F0Y1", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-111027-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111027-16", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000099500", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000099500", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100537161", "url": "https://www.ncbi.nlm.nih.gov/gene/100537161", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001304", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001304", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016186", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016186", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR016187", "url": "https://www.ebi.ac.uk/interpro/entry/IPR016187", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR018378", "url": 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"categories": [ "Protein Classification" ] }, { "id": "PF00059", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00059", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "R-DRE-114608", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-114608", "database": "Reactome", "categories": [ "Enzyme and Pathway" ] }, { "id": "XP_003200569", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200569", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7F0Y1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F0Y1-1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y1-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-111027-16", "url": "https://zfin.org/ZDB-GENE-111027-16", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTLRDGRFLLPLLLLTLFTHSSLQQQNTSKKKTPDKKDSESRVSAALEDLQQQISDIVEELNLLKEQQALQTVCLKGTKIHGKCFLADSMKKRYHTANEDCIAKGGILATPLSSAQNTQLYEYMRQSISADAEIWLGVNDMQTEGLWTDQTGSAIRYKNWKLPQPDGGSAQNCAVLTSGGKWLDESCREERASICEFNIV", "length": 200, "header": "tr|E7F0Y1-1|E7F0Y1_DANRE Isoform 1 of Tetranectin OS=Danio rerio OX=7955 GN=clec3bb PE=4 SV=1 CANONICAL=E7F0Y1-1" }, "isoforms": [ { "isoform_ac": "E7F0Y1-1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y1/entry#E7F0Y1-1", "sequence": { "sequence": "MTLRDGRFLLPLLLLTLFTHSSLQQQNTSKKKTPDKKDSESRVSAALEDLQQQISDIVEELNLLKEQQALQTVCLKGTKIHGKCFLADSMKKRYHTANEDCIAKGGILATPLSSAQNTQLYEYMRQSISADAEIWLGVNDMQTEGLWTDQTGSAIRYKNWKLPQPDGGSAQNCAVLTSGGKWLDESCREERASICEFNIV", "length": 200, "header": "tr|E7F0Y1-1|E7F0Y1_DANRE Isoform 1 of Tetranectin OS=Danio rerio OX=7955 GN=clec3bb PE=4 SV=1 CANONICAL=E7F0Y1-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100537161", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100537161", "resource": "KEGG Pathway" }, { "id": "R-DRE-114608", "name": "", "url": "https://www.reactome.org/PathwayBrowser/#R-DRE-114608", "resource": "Reactome", "description": "Platelet degranulation" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8M9PDC0-1", "protein_name": "Tetranectin", "gene_name": "clec3ba", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MFGLICTSSVLLCMFFSTGCTYAEEKMDLKAVKFLLCVICLVKSSPEQSLTKRKNGKKESNSAAIEELKKQIDQIIQDLNLLKEQQALQTVCLKGFKIPGKCFLVDTVKKDFHSANDDCIAKGGILSTPMSGHENDQLQEYVQQTVGPETHIWLGVNDMIKEGEWIDLTGSPIRFKNWESEITHQPDGGRTHNCAVLSSTANGKWFDEDCRGEKASVCQFNIV", "length": 223 }, "evidence": [ { "id": "MGI:104540", "url": "https://alliancegenome.org/gene/MGI:104540#orthology", "database": "AGR" }, { "id": "HGNC:11891", "url": "https://alliancegenome.org/gene/HGNC:11891#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "P05452-1", "protein_name": "Tetranectin", "gene_name": "CLEC3B", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MELWGAYLLLCLFSLLTQVTTEPPTQKPKKIVNAKKDVVNTKMFEELKSRLDTLAQEVALLKEQQALQTVCLKGTKVHMKCFLAFTQTKTFHEASEDCISRGGTLGTPQTGSENDALYEYLRQSVGNEAEIWLGLNDMAAEGTWVDMTGARIAYKNWETEITAQPDGGKTENCAVLSGAANGKWFDKRCRDQLPYICQFGIV", "length": 202 }, "evidence": [ { "id": "MGI:104540", "url": "https://alliancegenome.org/gene/MGI:104540#orthology", "database": "AGR" }, { "id": "HGNC:11891", "url": "https://alliancegenome.org/gene/HGNC:11891#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111027-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111027-16#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P43025-1", "protein_name": "Tetranectin", "gene_name": "Clec3b", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MGFWGTYLLFCLFSFLSQLTAESPTPKAKKAANAKKDLVSSKMFEELKNRMDVLAQEVALLKEKQALQTVCLKGTKVNLKCLLAFTQPKTFHEASEDCISQGGTLGTPQSELENEALFEYARHSVGNDANIWLGLNDMAAEGAWVDMTGGLLAYKNWETEITTQPDGGKAENCAALSGAANGKWFDKRCRDQLPYICQFAIV", "length": 202 }, "evidence": [ { "id": "MGI:104540", "url": "https://alliancegenome.org/gene/MGI:104540#orthology", "database": "AGR" }, { "id": "HGNC:11891", "url": "https://alliancegenome.org/gene/HGNC:11891#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-111027-16", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-111027-16#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "extracellular space", "id": "GO:0005615", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0005615", "evidence": [ { "database": "UniProtKB", "id": "E7F0Y1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y1" } ], "pmid": "" } ] }, { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "carbohydrate binding", "id": "GO:0030246", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030246", "evidence": [ { "database": "UniProtKB", "id": "E7F0Y1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y1" } ], "pmid": "" } ] }, { "name": "Biological Process", "total": 2, "go_terms": [ { "name": "ossification", "id": "GO:0001503", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0001503", "evidence": [ { "database": "UniProtKB", "id": "E7F0Y1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y1" } ], "pmid": "" }, { "name": "bone mineralization", "id": "GO:0030282", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0030282", "evidence": [ { "database": "UniProtKB", "id": "E7F0Y1", "url": "https://www.uniprot.org/uniprotkb/E7F0Y1" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 27, "end_pos": 29, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F0Y1", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F0Y1" }, { "id": "PS50041", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50041" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "C-type lectin", "eco_id": "ECO_0000259", "start_pos": 80, "end_pos": 196, "start_aa": "Ile", "end_aa": "Glu", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 27, "end_pos": 29 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F125-1", "uniprot_ac": "E7F125", "uniprot_id": "E7F125_DANRE", "mass": { "chemical_mass": 32821.0, "monoisotopic_mass": 32821.0 }, "refseq": { "ac": "XP_009304423", "name": "interferon-induced protein 44-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304423" }, "gene_names": [ { "name": "ifi44a1", "type": "recommended", "evidence": [ { "id": "E7F125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F125" } ] }, { "name": "ifi44a1", "type": "synonym", "evidence": [ { "id": "XP_009304423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304423" } ] } ], "protein_names": [ { "name": "Interferon-induced protein 44-like", "type": "synonym", "evidence": [ { "id": "E7F125", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F125/entry#names_and_taxonomy" } ] }, { "name": "interferon-induced protein 44-like", "type": "synonym", "evidence": [ { "id": "XP_009304423", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304423" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133176) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_009304423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304423" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F125", "url": "https://www.uniprot.org/uniprotkb/E7F125" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ifi44a1", "url": "https://www.uniprot.org/uniprotkb/E7F125", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-090312-156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-090312-156", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000029720", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000029720", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd00882", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00882", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "100148554", "url": "https://www.ncbi.nlm.nih.gov/gene/100148554", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR027417", "url": "https://www.ebi.ac.uk/interpro/entry/IPR027417", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100148554", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148554", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "KEWRITP", "url": "https://omabrowser.org/oma/group/KEWRITP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F125", "url": "https://www.orthodb.org/?gene=E7F125", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR14241", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14241", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR14241:SF1", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR14241:SF1", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_009304423", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_009304423", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7F125", "url": "https://www.uniprot.org/uniprotkb/E7F125", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F125-1", "url": "https://www.uniprot.org/uniprotkb/E7F125-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-090312-156", "url": "https://zfin.org/ZDB-GENE-090312-156", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MGGSKSKQTPTDDSSKKLDKPWRNFDWEQKDRLKERLEKFQLSSPDLNCVKLLVAGQIGAGKSSFINSVNSAFQGQIVCDAQADAQSAASHSYTKKLEGYRIKNADADLPFEICDVMGLEPQELSGLQPEDVVKIIHGHVKEGYKFTENPITSKSESYNEIPSLSDQAFCLVYVVDANTIQLKSDDTTLLKKLRLIRKKLTDEGIPQVIVLTKVDEACKLVESNLKDIYYSITIKKKMEFCSAEIGVPMTMIFPVKNYHNEVDTDDSVDALILKAFDQIVRSANARLSRGSSNE", "length": 294, "header": "tr|E7F125-1|E7F125_DANRE Isoform 1 of Interferon-induced protein 44-like OS=Danio rerio OX=7955 GN=ifi44a1 PE=4 SV=1 CANONICAL=E7F125-1" }, "isoforms": [ { "isoform_ac": "E7F125-1", "url": "https://www.uniprot.org/uniprotkb/E7F125/entry#E7F125-1", "sequence": { "sequence": "MGGSKSKQTPTDDSSKKLDKPWRNFDWEQKDRLKERLEKFQLSSPDLNCVKLLVAGQIGAGKSSFINSVNSAFQGQIVCDAQADAQSAASHSYTKKLEGYRIKNADADLPFEICDVMGLEPQELSGLQPEDVVKIIHGHVKEGYKFTENPITSKSESYNEIPSLSDQAFCLVYVVDANTIQLKSDDTTLLKKLRLIRKKLTDEGIPQVIVLTKVDEACKLVESNLKDIYYSITIKKKMEFCSAEIGVPMTMIFPVKNYHNEVDTDDSVDALILKAFDQIVRSANARLSRGSSNE", "length": 294, "header": "tr|E7F125-1|E7F125_DANRE Isoform 1 of Interferon-induced protein 44-like OS=Danio rerio OX=7955 GN=ifi44a1 PE=4 SV=1 CANONICAL=E7F125-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100148554", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148554", "resource": "KEGG Pathway" } ], "orthologs": [], "go_annotation": { "categories": [ { "name": "Biological Process", "total": 1, "go_terms": [ { "name": "immune response", "id": "GO:0006955", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0006955", "evidence": [ { "database": "UniProtKB", "id": "E7F125", "url": "https://www.uniprot.org/uniprotkb/E7F125" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F142-1", "uniprot_ac": "E7F142", "uniprot_id": "E7F142_DANRE", "mass": { "chemical_mass": 27040.0, "monoisotopic_mass": 27040.0 }, "refseq": { "ac": "NP_001258553", "name": "TLC domain-containing protein 5a", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258553" }, "gene_names": [ { "name": "tlcd5a", "type": "recommended", "evidence": [ { "id": "E7F142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F142" } ] }, { "name": "fj54b05", "type": "synonym", "evidence": [ { "id": "NP_001258553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258553" }, { "id": "E7F142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F142" } ] }, { "name": "id:ibd5089", "type": "synonym", "evidence": [ { "id": "NP_001258553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258553" }, { "id": "E7F142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F142" } ] }, { "name": "tlcd5a", "type": "synonym", "evidence": [ { "id": "NP_001258553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258553" } ] }, { "name": "tmem136a", "type": "synonym", "evidence": [ { "id": "NP_001258553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258553" }, { "id": "E7F142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F142" } ] }, { "name": "wu:fj54b05", "type": "synonym", "evidence": [ { "id": "NP_001258553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258553" }, { "id": "E7F142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F142" } ] } ], "protein_names": [ { "name": "TLC domain-containing protein 5a", "type": "synonym", "evidence": [ { "id": "NP_001258553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258553" }, { "id": "E7F142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F142/entry#names_and_taxonomy" } ] }, { "name": "transmembrane protein 136a", "type": "synonym", "evidence": [ { "id": "NP_001258553", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258553" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01033435.1, GDQQ01056892.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505371, SAMEA3505375 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000015.1. On Oct 28, 2012 this sequence version replaced XP_690813.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.", "evidence": [ { "database": "RefSeq", "id": "NP_001258553", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258553" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F142", "url": "https://www.uniprot.org/uniprotkb/E7F142" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tlcd5a", "url": "https://www.uniprot.org/uniprotkb/E7F142", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-000607-58", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-000607-58", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000024920", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000024920", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "562331", "url": "https://www.ncbi.nlm.nih.gov/gene/562331", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR006634", "url": "https://www.ebi.ac.uk/interpro/entry/IPR006634", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR042512", "url": "https://www.ebi.ac.uk/interpro/entry/IPR042512", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "YEACEWT", "url": "https://omabrowser.org/oma/group/YEACEWT/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F142", "url": "https://www.orthodb.org/?gene=E7F142", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR31898", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31898", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR31898:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR31898:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF03798", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF03798", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001258553", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001258553", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7F142", "url": "https://www.uniprot.org/uniprotkb/E7F142", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F142-1", "url": "https://www.uniprot.org/uniprotkb/E7F142-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-000607-58", "url": "https://zfin.org/ZDB-GENE-000607-58", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MSPLVLGVGVCLAGWIALYALLCYTNGSCGYEWNCRLVTLFHGILAVCITAYIGYIDGPWPFTYPGTKNTPLQISALVVSLGYFIFDMAWCVYFRTEGLVMLAHHTMSILGILLTLWLEESGIESCAVLFGSEITNPLLQTRWFLKHSGRYDSILGDVVDILFVALFVFMRIFVGGAMLYCELISPRPKFIIKCGGVAMYALSWVFMADIVRFTYRKYQVWMNRHKMMAEVNGLNVKRD", "length": 239, "header": "tr|E7F142-1|E7F142_DANRE Isoform 1 of TLC domain-containing protein 5a OS=Danio rerio OX=7955 GN=tlcd5a PE=4 SV=1 CANONICAL=E7F142-1" }, "isoforms": [ { "isoform_ac": "E7F142-1", "url": "https://www.uniprot.org/uniprotkb/E7F142/entry#E7F142-1", "sequence": { "sequence": "MSPLVLGVGVCLAGWIALYALLCYTNGSCGYEWNCRLVTLFHGILAVCITAYIGYIDGPWPFTYPGTKNTPLQISALVVSLGYFIFDMAWCVYFRTEGLVMLAHHTMSILGILLTLWLEESGIESCAVLFGSEITNPLLQTRWFLKHSGRYDSILGDVVDILFVALFVFMRIFVGGAMLYCELISPRPKFIIKCGGVAMYALSWVFMADIVRFTYRKYQVWMNRHKMMAEVNGLNVKRD", "length": 239, "header": "tr|E7F142-1|E7F142_DANRE Isoform 1 of TLC domain-containing protein 5a OS=Danio rerio OX=7955 GN=tlcd5a PE=4 SV=1 CANONICAL=E7F142-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "A gene expression screen in zebrafish embryogenesis.", "journal": "Genome Res.", "date": "2001", "authors": "Kudoh T, Tsang M, Hukriede N A, Chen X, Dedekian M, Clarke C J, Kiang A, Schultz S, Epstein J A, Toyama R, Dawid I B", "evidence": [ { "database": "UniProtKB", "id": "E7F142", "url": "https://www.uniprot.org/uniprotkb/E7F142" } ], "reference": [ { "type": "PubMed", "id": "11731487", "url": "https://glygen.org/publication/PubMed/11731487" } ] }, { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7F142", "url": "https://www.uniprot.org/uniprotkb/E7F142" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [], "orthologs": [ { "uniprot_canonical_ac": "D3ZNW9-1", "protein_name": "TLC domain containing 5", "gene_name": "Tlcd5", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MAVGLCVQVLCSLGGWLSLYTSLCGLNKHRSCEWSCRLVTFTHGILSIGLSAYIGFIDGPWPFTHPGSPNTPLQVHVLCLTLGYFIFDLGWCIYFQSEGALMLAHHTLSILGIIMALALGESGTEVNAVLFGSEITNPLLQMRWFLRETGHYHSFTGDVVDFLFVALFTGVRIGVGAHLLFCEMVSPTPRWFVKVGGVAMYAVSWCFMVSIWRFAWKKSVKKYHAWRSRRNEERQLRHNGHLKTH", "length": 245 }, "evidence": [ { "id": "MGI:2685030", "url": "https://alliancegenome.org/gene/MGI:2685030#orthology", "database": "AGR" }, { "id": "HGNC:28280", "url": "https://alliancegenome.org/gene/HGNC:28280#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "F4HWQ7-1", "protein_name": "TRAM, LAG1 and CLN8 (TLC) lipid-sensing domain containing protein", "gene_name": "", "tax_id": 3702, "organism": "Arabidopsis thaliana", "sequence": { "sequence": "MEEEYIRIISITTIRIISWGLIFILVRRIFSSYSFDFSTRIVSTLHATIAVTLATLSIQDWSCPVCPIASTSSLRQMETLAFSLSYMIYDLICSHFDQVLSIDNAVHHSVCILGFVAGLFYQKCGSEMVAAIWITEISSPFLHLREILKEIGCRDTDLNLAADVFFATIFSVARMVGGPYLVYVTIPADNPILIKVMGLGLQLVSAFYKLLKMMRYKFIKRSMSTKKST", "length": 229 }, "evidence": [ { "id": "E7F142", "url": "https://omabrowser.org/oma/group/E7F142/", "database": "OMA" } ], "glygen_name": "Arabidopsis", "common_name": "Mouse-ear cress" }, { "uniprot_canonical_ac": "Q1LXV8-1", "protein_name": "TLC domain-containing protein 5", "gene_name": "tlcd5", "tax_id": 7955, "organism": "Danio rerio", "sequence": { "sequence": "MPLFIVETSCSLISWLFLYLLLCHLNSGRDSEWNCRLVTLFHGILIICLTAYIGFIAGPWPFTHPGTENTYFQILTLVLSLGYFLFDMAWCVYFRTEGPVMLAHHTMSIFGILLALGLGESGIETCAVLFGSEITNPLLQARWFLKRMGCYDSLAGDVVDLLFILLFASVRIGVGSRMLYCELTSPKPSLIVKVGGVAIYTLSWIFMVDIARFACRKTCGKYRRWKEQYKLDGVNGHAVKIK", "length": 242 }, "evidence": [ { "id": "MGI:2685030", "url": "https://alliancegenome.org/gene/MGI:2685030#orthology", "database": "AGR" }, { "id": "HGNC:28280", "url": "https://alliancegenome.org/gene/HGNC:28280#orthology", "database": "AGR" } ], "glygen_name": "Zebrafish", "common_name": "Zebrafish" }, { "uniprot_canonical_ac": "Q3TYE7-1", "protein_name": "TLC domain-containing protein 5", "gene_name": "Tlcd5", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MAVGLCVQVLCSLGGWLSLYTSFCCLNKHRSCEWSCRLVTFTHGVLSIGLSAYIGFIDGPWPFTHPGSPNTPLQVHVLCLTLGYFIFDLGWCIYFQSEGPLMLAHHTLSILGIIMALALGESGTEVNAVLFGSEITNPLLQMRWFLRETGHYHSFTGDVVDFLFVALFTGVRIGVGAHLLFCEMVSPTPKWFVKVGGVAMYAVSWCFMVSIWRFAWKKSIKKYHAWRSRRNEERQLRHNGHLKTH", "length": 245 }, "evidence": [ { "id": "MGI:2685030", "url": "https://alliancegenome.org/gene/MGI:2685030#orthology", "database": "AGR" }, { "id": "HGNC:28280", "url": "https://alliancegenome.org/gene/HGNC:28280#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-000607-58", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-000607-58#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q6ZRR5-1", "protein_name": "TLC domain-containing protein 5", "gene_name": "TLCD5", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MALALCLQVLCSLCGWLSLYISFCHLNKHRSYEWSCRLVTFTHGVLSIGLSAYIGFIDGPWPFTHPGSPNTPLQVHVLCLTLGYFIFDLGWCVYFQSEGALMLAHHTLSILGIIMALVLGESGTEVNAVLFGSELTNPLLQMRWFLRETGHYHSFTGDVVDFLFVALFTGVRIGVGACLLFCEMVSPTPKWFVKAGGVAMYAVSWCFMFSIWRFAWRKSIKKYHAWRSRRSEERQLKHNGHLKIH", "length": 245 }, "evidence": [ { "id": "MGI:2685030", "url": "https://alliancegenome.org/gene/MGI:2685030#orthology", "database": "AGR" }, { "id": "HGNC:28280", "url": "https://alliancegenome.org/gene/HGNC:28280#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-000607-58", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-000607-58#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": { "categories": [ { "name": "Cellular Component", "total": 1, "go_terms": [ { "name": "membrane", "id": "GO:0016020", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0016020", "evidence": [ { "database": "UniProtKB", "id": "E7F142", "url": "https://www.uniprot.org/uniprotkb/E7F142" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 26, "end_pos": 28, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F142", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F142" }, { "id": "PS50922", "database": "PROSITE", "url": "https://prosite.expasy.org/PS50922" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "TLC", "eco_id": "ECO_0000259", "start_pos": 28, "end_pos": 219, "start_aa": "Ser", "end_aa": "Gln", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" }, { "name": "homologset.oma", "label": "OMA Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 26, "end_pos": 28 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 2 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F1E2-1", "uniprot_ac": "E7F1E2", "uniprot_id": "E7F1E2_DANRE", "mass": { "chemical_mass": 20086.0, "monoisotopic_mass": 20086.0 }, "refseq": { "ac": "NP_001186943", "name": "thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186943" }, "gene_names": [ { "name": "tstd3", "type": "recommended", "evidence": [ { "id": "E7F1E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1E2" } ] }, { "name": "si:dkey-165n16.1", "type": "synonym", "evidence": [ { "id": "NP_001186943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186943" }, { "id": "E7F1E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1E2" } ] }, { "name": "tstd3", "type": "synonym", "evidence": [ { "id": "NP_001186943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186943" } ] } ], "protein_names": [ { "name": "Sulfurtransferase", "type": "recommended", "evidence": [ { "id": "E7F1E2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1E2/entry#names_and_taxonomy" } ] }, { "name": "heat shock protein 67b2-like", "type": "synonym", "evidence": [ { "id": "NP_001186943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186943" } ] }, { "name": "thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "type": "synonym", "evidence": [ { "id": "NP_001186943", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186943" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: EH506740.1, EH485063.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from EH432581.1, EH545230.1 and EH532900.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001186943", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186943" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F1E2", "url": "https://www.uniprot.org/uniprotkb/E7F1E2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "tstd3", "url": "https://www.uniprot.org/uniprotkb/E7F1E2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-100922-224", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100922-224", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000087048", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000087048", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "cd01519", "url": "https://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd01519", "database": "CDD", "categories": [ "Protein Classification" ] }, { "id": "564087", "url": "https://www.ncbi.nlm.nih.gov/gene/564087", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR001307", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001307", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR001763", "url": "https://www.ebi.ac.uk/interpro/entry/IPR001763", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR036873", "url": "https://www.ebi.ac.uk/interpro/entry/IPR036873", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:564087", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564087", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "WAERELI", "url": "https://omabrowser.org/oma/group/WAERELI/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F1E2", "url": "https://www.orthodb.org/?gene=E7F1E2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR44086", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44086", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR44086:SF10", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR44086:SF10", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF00581", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF00581", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001186943", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001186943", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7F1E2", "url": "https://www.uniprot.org/uniprotkb/E7F1E2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F1E2-1", "url": "https://www.uniprot.org/uniprotkb/E7F1E2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-100922-224", "url": "https://zfin.org/ZDB-GENE-100922-224", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MALNVCSRLTRNVVRVLANRSAIPVTRPLTRSSWTHLRYLHNISIIRYDSVSLRNFSSSSQPSVDVSYEQLKKLLVSGSSVVIDVREPWELREYGNIQGSINVPLGQVNGALQLTPDEFKEKYGGDMPSKSQNIVFSCLAGVRSKHALEAAVSLGYTKVQHFPGGWQEWAERELIQTKK", "length": 179, "header": "tr|E7F1E2-1|E7F1E2_DANRE Isoform 1 of Sulfurtransferase OS=Danio rerio OX=7955 GN=tstd3 PE=1 SV=1 CANONICAL=E7F1E2-1" }, "isoforms": [ { "isoform_ac": "E7F1E2-1", "url": "https://www.uniprot.org/uniprotkb/E7F1E2/entry#E7F1E2-1", "sequence": { "sequence": "MALNVCSRLTRNVVRVLANRSAIPVTRPLTRSSWTHLRYLHNISIIRYDSVSLRNFSSSSQPSVDVSYEQLKKLLVSGSSVVIDVREPWELREYGNIQGSINVPLGQVNGALQLTPDEFKEKYGGDMPSKSQNIVFSCLAGVRSKHALEAAVSLGYTKVQHFPGGWQEWAERELIQTKK", "length": 179, "header": "tr|E7F1E2-1|E7F1E2_DANRE Isoform 1 of Sulfurtransferase OS=Danio rerio OX=7955 GN=tstd3 PE=1 SV=1 CANONICAL=E7F1E2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [ { "title": "RFX transcription factors are essential for hearing in mice.", "journal": "Nat. Commun.", "date": "2015", "authors": "Elkon Ran, Milon Beatrice, Morrison Laura, Shah Manan, Vijayakumar Sarath, Racherla Manoj, Leitch Carmen C, Silipino Lorna, Hadi Shadan, Weiss-Gayet Mich\u00e8le, Barras Emmanu\u00e8le, Schmid Christoph D, Ait-Lounis Aouatef, Barnes Ashley, Song Yang, Eisenman David J, Eliyahu Efrat, Frolenkov Gregory I, Strome Scott E, Durand B\u00e9n\u00e9dicte, Zaghloul Norann A, Jones Sherri M, Reith Walter, Hertzano Ronna", "evidence": [ { "database": "UniProtKB", "id": "E7F1E2", "url": "https://www.uniprot.org/uniprotkb/E7F1E2" } ], "reference": [ { "type": "PubMed", "id": "26469318", "url": "https://glygen.org/publication/PubMed/26469318" } ] } ], "pathway": [ { "id": "dre:564087", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:564087", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "G3V8W9-1", "protein_name": "Thiosulfate sulfurtransferase like domain containing 3", "gene_name": "Tstd3", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MLARLVLGTSCRAVLGSVEPALGGLKSRWGSSQHFCSTLSKDVTYRELKNLLNSKDIMLIDVRNTWEILEHGKIPGSVNIPLDEVGEALQMNPREFKEKYGEEKPSKSDRLVFSCLAGVRSKKAMDTAISLGFNSAQHYIGGWTEWVTYEISEKKQS", "length": 157 }, "evidence": [ { "id": "MGI:1924282", "url": "https://alliancegenome.org/gene/MGI:1924282#orthology", "database": "AGR" }, { "id": "HGNC:40910", "url": "https://alliancegenome.org/gene/HGNC:40910#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "H0UI37-1", "protein_name": "Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "gene_name": "TSTD3", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MKIEKCGWSEGLTSIKGNCHNFYTAISKDVTYKELKNLLNSKNIMLIDVREIWEILEYQKIPESINVPLDEVGEALQMNPRDFKEKYNEVKPSKSDS", "length": 97 }, "evidence": [ { "id": "MGI:1924282", "url": "https://alliancegenome.org/gene/MGI:1924282#orthology", "database": "AGR" }, { "id": "HGNC:40910", "url": "https://alliancegenome.org/gene/HGNC:40910#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100922-224", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100922-224#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "P22978-1", "protein_name": "Rhodanese domain-containing protein CG4456", "gene_name": "", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATYEQVKDVPNHPDVYLIDVRRKEELQQTGFIPASINIPLDELDKALNLDGSAFKNKYGRSKPEKQSPIIFTCRSGNRVLEAEKIAKSQGYSNVVIYKGSWNEWAQKEGL", "length": 111 }, "evidence": [ { "id": "MGI:1924282", "url": "https://alliancegenome.org/gene/MGI:1924282#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q08742-1", "protein_name": "Thiosulfate sulfurtransferase RDL2, mitochondrial", "gene_name": "RDL2", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MFKHSTGILSRTVSARSPTLVLRTFTTKAPKIYTFDQVRNLVEHPNDKKLLVDVREPKEVKDYKMPTTINIPVNSAPGALGLPEKEFHKVFQFAKPPHDKELIFLCAKGVRAKTAEELARSYGYENTGIYPGSITEWLAKGGADVKPKK", "length": 149 }, "evidence": [ { "id": "MGI:1924282", "url": "https://alliancegenome.org/gene/MGI:1924282#orthology", "database": "AGR" }, { "id": "HGNC:40910", "url": "https://alliancegenome.org/gene/HGNC:40910#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q12305-1", "protein_name": "Thiosulfate:glutathione sulfurtransferase", "gene_name": "RDL1", "tax_id": 559292, "organism": "Saccharomyces cerevisiae S288C", "sequence": { "sequence": "MWKAVMNAWNGTESQSKNVSNIQSYSFEDMKRIVGKHDPNVVLVDVREPSEYSIVHIPASINVPYRSHPDAFALDPLEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSHGYSNTSLYPGSMNDWVSHGGDKLDL", "length": 139 }, "evidence": [ { "id": "MGI:1924282", "url": "https://alliancegenome.org/gene/MGI:1924282#orthology", "database": "AGR" }, { "id": "HGNC:40910", "url": "https://alliancegenome.org/gene/HGNC:40910#orthology", "database": "AGR" } ], "glygen_name": "Yeast", "common_name": "Baker's yeast" }, { "uniprot_canonical_ac": "Q9D0B5-1", "protein_name": "Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 3", "gene_name": "Tstd3", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MLARLVLGTSGRAALGSVEPALGGLKSIWRCSQAFCSTPKGVTYRELKSLLNSKDIMLIDVRNTLEILEQGKIPGSINIPLDEVGEALQMNPVDFKEKYCQVKPSKSDRLVFSCLAGVRSKKAMDTAISLGFNSAQHYAGGWKEWVTYEISEEKQES", "length": 157 }, "evidence": [ { "id": "MGI:1924282", "url": "https://alliancegenome.org/gene/MGI:1924282#orthology", "database": "AGR" }, { "id": "HGNC:40910", "url": "https://alliancegenome.org/gene/HGNC:40910#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-100922-224", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-100922-224#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "Q9VCD9-1", "protein_name": "Rhodanese domain-containing protein", "gene_name": "BcDNA:RE30346", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MMMRHCMMALRVARSQIPFSTARNTQSNLLQRFYSQAPQIGIVDYDVVKKLPSEPQKLLIDVREPEELKETGQIPASINIPLGVVSQELAASEQLFKSKYGREKPKPETEIIFHCKIGKRSLKAAEAAAALGFKNVKNYQGSWLDWAEREGLPK", "length": 154 }, "evidence": [ { "id": "MGI:1924282", "url": "https://alliancegenome.org/gene/MGI:1924282#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q9VG33-1", "protein_name": "Sulfurtransferase", "gene_name": "Tst1", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MATYEEVKDIPNHPEKYLFDVRNESELKETGVLPASINIPLSELEKALNLPEEDFAQTYGRVKPAVDAVLIFSCKAGGRAARAANLASTLGFTNAKAYAGSWTEWQAKQS", "length": 110 }, "evidence": [ { "id": "MGI:1924282", "url": "https://alliancegenome.org/gene/MGI:1924282#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": 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"field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 1 } ], "sort_fields": [ "title", "journal", "date", "authors" ] } ] }, { "uniprot_canonical_ac": "E7F1E7-1", "uniprot_ac": "E7F1E7", "uniprot_id": "E7F1E7_DANRE", "mass": { "chemical_mass": 72587.0, "monoisotopic_mass": 72587.0 }, "refseq": { "ac": "XP_005155764", "name": "harmonin-binding protein USHBP1 isoform X1", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155764" }, "gene_names": [ { "name": "ushbp1", "type": "recommended", "evidence": [ { "id": "E7F1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1E7" } ] }, { "name": "ushbp1", "type": "synonym", "evidence": [ { "id": "XP_005155764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155764" } ] } ], "protein_names": [ { "name": "Harmonin-binding protein USHBP1 isoform X1", "type": "synonym", "evidence": [ { "id": "E7F1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1E7/entry#names_and_taxonomy" } ] }, { "name": "harmonin-binding protein USHBP1 isoform X1", "type": "synonym", "evidence": [ { "id": "XP_005155764", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155764" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133186) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_005155764", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155764" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F1E7", "url": "https://www.uniprot.org/uniprotkb/E7F1E7" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ushbp1", "url": "https://www.uniprot.org/uniprotkb/E7F1E7", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-121024-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121024-2", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000089071", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000089071", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "100148935", "url": "https://www.ncbi.nlm.nih.gov/gene/100148935", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR019536", "url": "https://www.ebi.ac.uk/interpro/entry/IPR019536", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR040171", "url": "https://www.ebi.ac.uk/interpro/entry/IPR040171", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:100148935", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148935", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "PLIGHEP", "url": "https://omabrowser.org/oma/group/PLIGHEP/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F1E7", "url": "https://www.orthodb.org/?gene=E7F1E7", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR23347", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23347", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR23347:SF5", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR23347:SF5", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF10506", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10506", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "XP_005155764", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_005155764", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "A0AC58GRL0", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRL0", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GRL0-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRL0-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GRL9", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRL9", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "A0AC58GRL9-1", "url": "https://www.uniprot.org/uniprotkb/A0AC58GRL9-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F1E7", "url": "https://www.uniprot.org/uniprotkb/E7F1E7", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F1E7-1", "url": "https://www.uniprot.org/uniprotkb/E7F1E7-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-121024-2", "url": "https://zfin.org/ZDB-GENE-121024-2", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MTERSDSLVSVDSELAQCETEVNTLLQIISDLNRKMDSLQIPREMKACESEVQVSGCVLQQRPRSPACSLMSVETGPASVESVCGDSEGGSSELWNRLQTLLSALETSSGQGKKMLRLQTHNVEAISAKHLSAARESWVQATQVLEEMERDLGISYPSALPTDERRQYQREVLSLYKHNQDLNASLKSRQDELMGAEKTLVDLEDENKFLQEKVVDLKRKWLYGVSCSPPVSPSLSSSRTSSPCFSSPSYPGSPLLSRKLPSSRPDSPLPPSTIDSVLQAETEKMQRCLERLKARNERLSAALVRRKGESEQLSMSLSRQEADSSALHMALAYCEECEEAYSDLLSLYEARKQQHAATNSTPQPDLSKSKEENSKCESSSPPEGAADARPNSLSKQEFEDKAGVITQRISRLQQDRAAVCIPQRGKAGEDKISPDTGTLAGVRGRASSLSKNNKEEKAALRYELDTVREEMSEMRGNLRLLEKERRCLDMSLMVQSAQDSATSLILDSLRDELGERRAAQQRTAENLAKIEGGGGIPGPRNHSILRELQAALQREQLLRTRVATLRESLDSALTDCTTNRRINREEIARLSRYYNKVSSTYRSSRKKQKEQLWRLEKQIAVMSERHATQEAELSSTVEAMEWRREETVL", "length": 649, "header": "tr|E7F1E7-1|E7F1E7_DANRE Isoform 1 of Harmonin-binding protein USHBP1 isoform X1 OS=Danio rerio OX=7955 GN=ushbp1 PE=4 SV=2 CANONICAL=E7F1E7-1" }, "isoforms": [ { "isoform_ac": "A0AC58GRL0-1", "url": "https://www.uniprot.org/uniprotkb/E7F1E7/entry#A0AC58GRL0-1", "sequence": { "sequence": "MKACESEVQVSGCVLQQRPRSPACSLMSVETGPASVESVCGDSEGGSSELWNRLQTLLSALETSSGQGKKMLRLQTHNVEAISAKHLSAARESWVQATQVLEEMERDLGISYPSALPTDERRQYQREVLSLYKHNQDLNASLKSRQDELMGAEKTLVDLEDENKFLQEKVVDLKRKWLYGVSCSPPVSPSLSSSRTSSPCFSSPSYPGSPLLSRKLPSSRPDSPLPPSTIDSVLQAETEKMQRCLERLKARNERLSAALVRRKGESEQLSMSLSRQEADSSALHMALAYCEECEEAYSDLLSLYEARKQQHAATNSTPQPDLSKSKEENSKCESSSPPEGAADARPNSLSKQEFEDKAGVITQRISRLQQDRAAVCIPQRGKAGEDKISPDTGTLAGVRGRASSLSKNNKEEKAALRYELDTVREEMSEMRGNLRLLEKERRCLDMSLMVQSAQDSATSLILDSLRDELGERRAAQQRTAENLAKIEGGGGIPGPRNHSILRELQAALQREQLLRTRVATLRESLDSALTDCTTNRRINREEIARLSRYYNKVSSTYRSSRKKQKEQLWRLEKQIAVMSERHATQEAELSSTVEAMEWRREETVL", "length": 605, "header": "tr|A0AC58GRL0-1|A0AC58GRL0_DANRE Computationally mapped isoform of Harmonin-binding protein USHBP1 isoform X2 OS=Danio rerio OX=7955 GN=ushbp1 PE=4 SV=1 CANONICAL=E7F1E7-1" }, "locus": {} }, { "isoform_ac": "A0AC58GRL9-1", "url": "https://www.uniprot.org/uniprotkb/E7F1E7/entry#A0AC58GRL9-1", "sequence": { "sequence": "MQRCLERLKARNERLSAALVRRKGESEQLSMSLSRQEADSSALHMALAYCEECEEAYSDLLSLYEARKQQHAATNSTPQPDLSKSKEENSKCESSSPPEGAADARPNSLSKQEFEDKAGVITQRISRLQQDRAAVCIPQRGKAGEDKISPDTGTLAGVRGRASSLSKNNKEEKAALRYELDTVREEMSEMRGNLRLLEKERRCLDMSLMVQSAQDSATSLILDSLRDELGERRAAQQRTAENLAKIEGGGGIPGPRNHSILRELQAALQREQLLRTRVATLRESLDSALTDCTTNRRINREEIARLSRYYNKVSSTYRSSRKKQKEQLWRLEKQIAVMSERHATQEAELSSTVEAMEWRREETVL", "length": 365, "header": "tr|A0AC58GRL9-1|A0AC58GRL9_DANRE Computationally mapped isoform of Harmonin-binding protein USHBP1 isoform X3 OS=Danio rerio OX=7955 GN=ushbp1 PE=4 SV=1 CANONICAL=E7F1E7-1" }, "locus": {} }, { "isoform_ac": "E7F1E7-1", "url": "https://www.uniprot.org/uniprotkb/E7F1E7/entry#E7F1E7-1", "sequence": { "sequence": "MTERSDSLVSVDSELAQCETEVNTLLQIISDLNRKMDSLQIPREMKACESEVQVSGCVLQQRPRSPACSLMSVETGPASVESVCGDSEGGSSELWNRLQTLLSALETSSGQGKKMLRLQTHNVEAISAKHLSAARESWVQATQVLEEMERDLGISYPSALPTDERRQYQREVLSLYKHNQDLNASLKSRQDELMGAEKTLVDLEDENKFLQEKVVDLKRKWLYGVSCSPPVSPSLSSSRTSSPCFSSPSYPGSPLLSRKLPSSRPDSPLPPSTIDSVLQAETEKMQRCLERLKARNERLSAALVRRKGESEQLSMSLSRQEADSSALHMALAYCEECEEAYSDLLSLYEARKQQHAATNSTPQPDLSKSKEENSKCESSSPPEGAADARPNSLSKQEFEDKAGVITQRISRLQQDRAAVCIPQRGKAGEDKISPDTGTLAGVRGRASSLSKNNKEEKAALRYELDTVREEMSEMRGNLRLLEKERRCLDMSLMVQSAQDSATSLILDSLRDELGERRAAQQRTAENLAKIEGGGGIPGPRNHSILRELQAALQREQLLRTRVATLRESLDSALTDCTTNRRINREEIARLSRYYNKVSSTYRSSRKKQKEQLWRLEKQIAVMSERHATQEAELSSTVEAMEWRREETVL", "length": 649, "header": "tr|E7F1E7-1|E7F1E7_DANRE Isoform 1 of Harmonin-binding protein USHBP1 isoform X1 OS=Danio rerio OX=7955 GN=ushbp1 PE=4 SV=2 CANONICAL=E7F1E7-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:100148935", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:100148935", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "Q3T1I3-1", "protein_name": "Harmonin-binding protein USHBP1", "gene_name": "Ushbp1", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSARATRPRSRRGRHPLPGELDPVAESSEEVDTTNGSFETKPELLQEHLGPSLQGPGNRIKEDCDVGSHGVLPLSPEERREPEVEAHQALQEAPLDTGPAEITAPNVYETLKCRLSSLEAVVAAWRRHSLSFSKPVEAEDRDPGAPGSFGNEEEASGPGQQEAAHFIERNAWLRLALGTREEELARTQASLQDAQAENETLQRQVQELEDSLMQLEASPPPSMLRAGRRNSNSSSSGAERRPWAPQDSPMAHPFLQRLRSDSSTQSFGCLSTQRPSPEMYLMEDQMGQLQGNIEKLKCFNRLLLAVLQGYKGRCESLSIKLGKREAEATALHLALQYSKDCEEVYEVLLALKTAGLGAGVGATNGDLQAAEKEASRLLVKKEVAMDVKTPQPSPEGSSVDKPTPEELAAQLHGYVQHLRERWALLKIPPVLDPATAPKPTMPHAEATVQTILEIQPGPTLPQLEKSQIQQDLAATRDGLADLVLRLQLAQREKRGLELREAALRAQGPALRLLLQQLRWEQAHLMGDGSSGGSSEDPSSEEEAGEDRQQHYQGPPALLGGQMGKVWDSETVSQELSASLTRAVDLRAQLQSLRRQLEQMAQKGRTRGAQSAELNRELCKAHSALALAFREAHRKQEEQCRKLEQQMARMQAQQAEELAVLTATARALGDPGAPQPVQTFL", "length": 680 }, "evidence": [ { "id": "MGI:1922920", "url": "https://alliancegenome.org/gene/MGI:1922920#orthology", "database": "AGR" }, { "id": "HGNC:24058", "url": "https://alliancegenome.org/gene/HGNC:24058#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "Q8N6Y0-1", "protein_name": "Harmonin-binding protein USHBP1", "gene_name": "USHBP1", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSARATRPRSRRGRHAPPGELDPVAESSEEVEAASGSSKPSFAPPPVSSGLEQLGPMEEVSGQGLGSRTDKKMDGGSGRELASAPEVPHKPAVEAHQAPEAALQYKETVPPGNGAPDVFQTLQHTLSSLEAAAAAWRHQPPSHSGPMEFEGTSEGGAGSLGKQEGAGSCQREAARLAERNAWLRLALSSREDELVRTQASLEAIRAEKETLQKEVQELQDSLLRLEPCPHLSHNQAGGSGSGSSSSEADREPWETQDSFSLAHPLLRRLRSHSSTQILGSLPNQPLSPEMHIMEAQMEQLRGSIEKLKCFNRLLSAVLQGYKGRCEGLSMQLGQREAEATALHLALQYSEHCEEAYRVLLALREADSGAGDEAPMSDLQAAEKEAWRLLAQEEAAMDAGAQQNPQPSPEGSSVDKPTPQEVAFQLRSYVQRLQERRSLMKILSEPGPTLAPMPTVPRAEAMVQAILGTQAGPALPRLEKTQIQQDLVAAREALADLMLRLQLVRREKRGLELREAALRALGPAHVLLLEQLRWERAELQAGGANSSGGHSSGGGSSGDEEEWYQGLPAVPGGTSGIDGGQVGRAWDPEKLAQELAASLTRTLDLQEQLQSLRRELEQVAQKGRARRSQSAELNRDLCKAHSALVLAFRGAHRKQEEQRRKLEQQMALMEAQQAEEVAVLEATARALGKPRPPLPPPQLGDTFL", "length": 703 }, "evidence": [ { "id": "MGI:1922920", "url": "https://alliancegenome.org/gene/MGI:1922920#orthology", "database": "AGR" }, { "id": "HGNC:24058", "url": "https://alliancegenome.org/gene/HGNC:24058#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121024-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121024-2#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8R370-1", "protein_name": "Harmonin-binding protein USHBP1", "gene_name": "Ushbp1", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSARATRPRSRRGRHPLPGELDPVAESSEEVDANNGRFETKPELHQEYLGPGLQSPRNWIKEGCDVGSHAVLSLSPEEQCEPEVEAHQVLQEAPLDSGPAEISVPSVYETLQCRLSSLEAVVAALRHHSLSFPKSVEAEDRDQGAPGPFGDEKEDAGPGQQEAARLIERNAWLRLALCNREDELACTQASLQDAQAEKETLQRQVQELEDSLMQMEASPPTPILRAGRRNSNSSTSGAERRPWVPQDSSMAHPFLQRLRSDSSTQSFGCLSTQHPAPETYLMEDQMGQLQGSIEKLKCFNRLLLAVLQGYKGRCESLSIKLAKREAEATALRLALQYSEDCEEVYEVLLALKMAGLGTGVGTTKGDLQAAEKEASRLLMKKEATMEVETPQPSSEGSGVDKPTPEELASQLHGYVQHLRERWALVKIPEELGPVTAPKATMPHAEATVQAILEIQPGPTLPHLEKSQIQQDLAATRDRLADLVLRLQLTQREKRGLELREAALRAQGPAHQLLLQQLRWERAHFAGDGSSGGSSEDPSSEEEAGEDRQQHYQGPLALLDGQMGKVWDSENVSQELSASLARAIDLRAQLQSLRQQLEQVTQKGRTRRVQSAELSRELCKAHSALALAFRGAHRKQEEQRLKLEQQVARLQAQQAEELAVLTATARALGKPGAPQPAQTFL", "length": 680 }, "evidence": [ { "id": "MGI:1922920", "url": "https://alliancegenome.org/gene/MGI:1922920#orthology", "database": "AGR" }, { "id": "HGNC:24058", "url": "https://alliancegenome.org/gene/HGNC:24058#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-121024-2", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-121024-2#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 183, "end_pos": 185, "annotation": "n_glycosylation_sequon" }, { "start_pos": 359, "end_pos": 361, "annotation": "n_glycosylation_sequon" }, { "start_pos": 541, "end_pos": 543, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F1E7", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1E7" }, { "id": "PF10506", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF10506" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Harmonin-binding protein USHBP1 PDZ-binding", "eco_id": "ECO_0000259", "start_pos": 284, "end_pos": 348, "start_aa": "Lys", "end_aa": "Tyr", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "isoformset.uniprotkb", "label": "Isoforms" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 183, "end_pos": 185 }, { "start_pos": 359, "end_pos": 361 }, { "start_pos": 541, "end_pos": 543 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F1G2-1", "uniprot_ac": "E7F1G2", "uniprot_id": "E7F1G2_DANRE", "mass": { "chemical_mass": 79391.0, "monoisotopic_mass": 79391.0 }, "refseq": { "ac": "XP_003200359", "name": "coiled-coil domain-containing protein 170", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200359" }, "gene_names": [ { "name": "ccdc170", "type": "recommended", "evidence": [ { "id": "E7F1G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1G2" } ] }, { "name": "ccdc170", "type": "synonym", "evidence": [ { "id": "XP_003200359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200359" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein 170", "type": "synonym", "evidence": [ { "id": "E7F1G2", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1G2/entry#names_and_taxonomy" } ] }, { "name": "coiled-coil domain-containing protein 170", "type": "synonym", "evidence": [ { "id": "XP_003200359", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200359" } ] } ], "function": [ { "annotation": "##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Status :: Full annotation Annotation Name :: GCF_049306965.1-RS_2025_04 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 10.3 Annotation Method :: Best-placed RefSeq; Gnomon; cmsearch; tRNAscan-SE Features Annotated :: Gene; mRNA; CDS; ncRNA Annotation Date :: 04/11/2025 ##Genome-Annotation-Data-END## MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_133192) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 24, 2014 this sequence version replaced XP_003200359.2. COMPLETENESS: full length.", "evidence": [ { "database": "RefSeq", "id": "XP_003200359", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200359" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F1G2", "url": "https://www.uniprot.org/uniprotkb/E7F1G2" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "ccdc170", "url": "https://www.uniprot.org/uniprotkb/E7F1G2", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-070112-162", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-162", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000016161", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000016161", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "791129", "url": "https://www.ncbi.nlm.nih.gov/gene/791129", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR039139", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039139", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:791129", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:791129", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "EQRTHNY", "url": "https://omabrowser.org/oma/group/EQRTHNY/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F1G2", "url": "https://www.orthodb.org/?gene=E7F1G2", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR18863", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18863", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR18863:SF4", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR18863:SF4", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "XP_003200359", "url": "https://www.ncbi.nlm.nih.gov/protein/XP_003200359", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7F1G2", "url": "https://www.uniprot.org/uniprotkb/E7F1G2", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F1G2-1", "url": "https://www.uniprot.org/uniprotkb/E7F1G2-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-070112-162", "url": "https://zfin.org/ZDB-GENE-070112-162", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "MMDESVIQQHLSHYKQATETAREELAALQAKHNSLQTQLSESQSRVVSQEETLRSLKDAVDRYKEKEARQESLIGSLRERNYNTEQEMISITSTRSIMDIRIQTLTKENQEIKEKIMQLEVESKQYVAECNKAKQEAAEAQRKCEEFISTLANKISVIATGKADPMDYIVSVVDACFKDRERLKNCVCALEESVKLYEVECKASRETVKRLATDVDREQTLSASRANELNSSRQELDLISLRKVSLERENQSAKVSLQEAEAALASAQQLCRHYENLSQDLQNKLQISQNEAKASHRHHGAFMKKVETLLDDHSLPGQHTEQDMLSALTDLCKRETSAQKSQMEMEVRLAEMVEQLSSIKEHQNTSEQKKQELLDRIQSLEDELINARVCKDGMNQDKQQYLRFVEQLSEMLKVDDVAAELGFDMRLEVILTRAQQLSRHEGTALLETKTQTYSLQRKLKEQKSRSESKDLYLELLRRKVQQLEEEKRSRSTLALEKDDAALSCKKLQKRVDRLQAELSTLRFSNTELKAQLSHTNQLQITVMEQKQTIEEQNKNLGKLEKKKVKTEQKLTSVTSELKSQELKARDEIQQAHRLLDTQSSAIADLTHTEKQLLDFYTVVSQMLGVHCTGCIPNYEVLRRLEVLIQSRQCHSTAHLHTCWNSPVSSINVDQSHEFKPQALPAASSPTASLINPH", "length": 693, "header": "tr|E7F1G2-1|E7F1G2_DANRE Isoform 1 of Coiled-coil domain-containing protein 170 OS=Danio rerio OX=7955 GN=ccdc170 PE=4 SV=1 CANONICAL=E7F1G2-1" }, "isoforms": [ { "isoform_ac": "E7F1G2-1", "url": "https://www.uniprot.org/uniprotkb/E7F1G2/entry#E7F1G2-1", "sequence": { "sequence": "MMDESVIQQHLSHYKQATETAREELAALQAKHNSLQTQLSESQSRVVSQEETLRSLKDAVDRYKEKEARQESLIGSLRERNYNTEQEMISITSTRSIMDIRIQTLTKENQEIKEKIMQLEVESKQYVAECNKAKQEAAEAQRKCEEFISTLANKISVIATGKADPMDYIVSVVDACFKDRERLKNCVCALEESVKLYEVECKASRETVKRLATDVDREQTLSASRANELNSSRQELDLISLRKVSLERENQSAKVSLQEAEAALASAQQLCRHYENLSQDLQNKLQISQNEAKASHRHHGAFMKKVETLLDDHSLPGQHTEQDMLSALTDLCKRETSAQKSQMEMEVRLAEMVEQLSSIKEHQNTSEQKKQELLDRIQSLEDELINARVCKDGMNQDKQQYLRFVEQLSEMLKVDDVAAELGFDMRLEVILTRAQQLSRHEGTALLETKTQTYSLQRKLKEQKSRSESKDLYLELLRRKVQQLEEEKRSRSTLALEKDDAALSCKKLQKRVDRLQAELSTLRFSNTELKAQLSHTNQLQITVMEQKQTIEEQNKNLGKLEKKKVKTEQKLTSVTSELKSQELKARDEIQQAHRLLDTQSSAIADLTHTEKQLLDFYTVVSQMLGVHCTGCIPNYEVLRRLEVLIQSRQCHSTAHLHTCWNSPVSSINVDQSHEFKPQALPAASSPTASLINPH", "length": 693, "header": "tr|E7F1G2-1|E7F1G2_DANRE Isoform 1 of Coiled-coil domain-containing protein 170 OS=Danio rerio OX=7955 GN=ccdc170 PE=4 SV=1 CANONICAL=E7F1G2-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:791129", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:791129", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A8C2MPS2-1", "protein_name": "Coiled-coil domain-containing protein 170 isoform X1", "gene_name": "Ccdc170", "tax_id": 10029, "organism": "Cricetulus griseus", "sequence": { "sequence": "MSHSSSSGSGSLERPSNASPPEETANHPMEFPGTWEQLNHYRNVAENVQSELAATLVKFECAQSELRDLRSKLLSKEVCCQELKAEVESYKENSARKSSLLISLRSRIQELQEESAALSASKIRTETSAHTTMKENQELMKKVLELDEKLQNCLKENEESKKQGLENLRRHEEFRTELCDCLSLDKKHEEASNEDLILKLRELCKENTLLKGQIVTLEETINVHEMEAKANRETISRLAAEVSREQTRAASWAMEKDKLNQDLLSAVDARTALEREAKLFQERLLVAQRAWDASKQELNQLRKNCQHLDLSLKASRDAAATSQSQNSSFREKLTVLLCNGLDMAVPTEDAILERIRELGIQEESKTRMVSQLEAQISELVEQLGNEAELHRKDLQRAQEAESKLEALQGQLSHLEGELLSGDVLRDNLNLEKQKYLQFLDQLSEKMKLGEIADDLGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKEVHMNLLRQKIAQLQQETQARTALAVERDEAHLTVRKLEKKVERMQKELSACREYNTELKAQLADTNELKIKTLEQTKVIEDLSKSRDNLEKLKEKAEKKLMLLKSKLDTAEEEAKADKGRMTAIMELVTSELETLKKSLEEAERREQQLVEFREVVSQTLGLNLTSLAVPDYEIIKCLERVVHSHHHHLVTCACLKDTSAEHDSCPKCCLELLH", "length": 718 }, "evidence": [ { "id": "E7F1G2", "url": "https://omabrowser.org/oma/group/E7F1G2/", "database": "OMA" } ], "glygen_name": "Hamster", "common_name": "Chinese hamster" }, { "uniprot_canonical_ac": "A0AAA9S743-1", "protein_name": "Coiled-coil domain containing 170", "gene_name": "CCDC170", "tax_id": 9913, "organism": "Bos taurus", "sequence": { "sequence": "MLSKEVSYQELKAEMESYKENNARKSSLLISLRDRVQELEEESAALATSKIRTEITAQSAIKENQELKKKVVELDEKLQKCLKENEENKNQVSQNCRKHEEFLAQLRDCLDPEKNEKASDEDLILKLGELCKENAFVKGQIVALEETINVHEMEAKASRETIMRLASEVNREQKKAASYIEEKGQLSQDLLGAMEAKEALEREVKVFQERLLAGQRVWDASKQELSLLKRSSLELEKSLKASLEATAASQTELSSFREKIAALLRGSSGTLRPSEDAILERIREMGSQEESGKQMVSQLEAQISKLVEQLGNESQFHQKALQRAQKAENQLEALQGRLTHLEEELVSGGVLQDDLHFEKQKYLKFLDQLSEKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKELHMNFLRQKIAHLEQEKQVRSAVMVERDEANVTIRKLQKKVERLQKELSVCQELNTELKAKLADTSELKIKTLEQTRAIEDLNKSRDKLEKMKEKAEKKLLSVKSELETTEHEAKENKERARNMLEVVTSEMKTLKKSLEEAGKRERQLMDFREVVSQMLGLNMMSLALPDYEIIKCLERLIHAHQHRFVPCACLKDETAKQDRPPQGHVQLLH", "length": 645 }, "evidence": [ { "id": "E7F1G2", "url": "https://omabrowser.org/oma/group/E7F1G2/", "database": "OMA" } ], "glygen_name": "Bovine", "common_name": "Bovine" }, { "uniprot_canonical_ac": "A0ABK0LHN4-1", "protein_name": "Coiled-coil domain containing 170", "gene_name": "Ccdc170", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MSHSSSLGSGSPECPRNASPPEGTADHHPEVPVTREQLNHYRNVAENVQSELAAALVRFECAQSELRELRSKMLSKEVCCQELKAEMESYKENSARKSSLLVSLRGRIQELQEESAAFSASKIRAEASAHAMMKENQELMKKVLELDEKLQDCSKANEESKKQGSETLRRHEEFRTQLRDCLSLDKKCEEAPDEDLVLKLKELCKENTSLKGQLTTLEETVSVHEMEAKANRETILRLAADVSREQTKAASWAEEKDKLNQDLLSAAEARTALEREAMLYQERLLASQRAWDASKQELNQLRKSCQQLDVSLKASREAATASQSQNACFREKLAALLCSRFDIAESTEDAILEKIRVLGIEEENQKRMASQLEAQISELVGKLGNESESHQKALQRAHEAEKKLEALQGQLSHLEGELLSGDVVRDNLNLEKQKYLKFLDQLSEKMKLGHIAADLGFDMRLDVVLARIEQLVHLESNAVIENKTMAHNLQRKLKTQKERLESKEVHMNLLRQKITQLQQEKEARSALAMERDEAHLSVRKLEKKVERMQKELSSCQEYNTELKAKLADTSELKIKTLEQTKAIEDLNQSRGELEKMKENAEKKLMLVMSELETTVQEAQANQERTRAMIELASSELRILKKSLDEAERREQQLADFREVVSSMLGLNVTSLALPDYEIIKCLERLIHSHHHHHHHHHFVPCACLKDMAAEQASPHSAT", "length": 718 }, "evidence": [ { "id": "HGNC:21177", "url": "https://alliancegenome.org/gene/HGNC:21177#orthology", "database": "AGR" }, { "id": "MGI:2685067", "url": "https://alliancegenome.org/gene/MGI:2685067#orthology", "database": "AGR" }, { "id": "E7F1G2", "url": "https://omabrowser.org/oma/group/E7F1G2/", "database": "OMA" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "D3YXL0-1", "protein_name": "Coiled-coil domain containing 170", "gene_name": "Ccdc170", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MSHSSSLGSGSPECPCNSSPPEGTASHRPEVPDTWEQLNHYRNVTENVQSELAAMLVKFECAQSELRELRSKMLSKEACCQELKVEMESYKESSARKSALLTSLRGRMEELQEESAAVSASKSRAEASVHAMMKENQELMKKVLELDEKLQNCSKENEESKKQGSEHLRRHEEFRAQLHDCLSLDKKHEEASDEDLILKLRELYKEPTFLKGQLATLEETVTVHEMEAKANRETIRRLAAEVSREQTKAASWAEEKDKLNQDLLSAVEGRTALEREVKLYQERLLASQRAWDASKQELTQLRKRCQELDVSLKASREATTASQSRNSCFREKLTALLCSRFDTAESTEDAILERIRELGIEEESQRRMASQLEAQISEFVGKLGNESESHQKALQRAHVAEKKLEALQSQLSHLEGELLSGDVVRDNLFLEKQKYLKFLDQLTEKMKLGHVAADLGFDVCLDVVLARIEQLVRLESNAVIENKTMAHNLQRKLKTQKERLESKEVHMNLLRQKIAQLQQEKEARSALAVERDEAHLAMRKLEKKLERMQKELSACQEHNTELKAKLADTNELKIKTLEQTKAIEDLNQSRDELEKMKENAEKKLMLVMSELENTEQEARAHQERSRAMIELASLELKTLRKSLDEAERRGMQLADFREVVSSMLGLNMTSHDPPDYEIIKCLERLLHSHRHHHHHHFVPCACLQDMAAEQGSCSHCRVEIPH", "length": 722 }, "evidence": [ { "id": "HGNC:21177", "url": "https://alliancegenome.org/gene/HGNC:21177#orthology", "database": "AGR" }, { "id": "MGI:2685067", "url": "https://alliancegenome.org/gene/MGI:2685067#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-162", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-162#orthology", "database": "AGR" }, { "id": "E7F1G2", "url": "https://omabrowser.org/oma/group/E7F1G2/", "database": "OMA" } ], "glygen_name": "Mouse", "common_name": "Mouse" }, { "uniprot_canonical_ac": "I3L7N5-1", "protein_name": "Coiled-coil domain containing 170", "gene_name": "CCDC170", "tax_id": 9823, "organism": "Sus scrofa", "sequence": { "sequence": "MSSSGPRRLQPIGPAAFGASPPAPEETYDRLLEVPVTREQLNHYRNVAETARSELAATLVKFESAQAELRDLQSKMRSKEVSCQELKAEMENYKESNARKASLLISLRDRVQELEEESVVLSTSKIRTEIAAHSAVKENQELKKNFVELDEKLQKCLKDNEENKKQVLQSCRKHEKFLAALRDSLDPEKKNEKASDEDLILKVGELCKENALVKGQIVALEETVSVHEMEAEASRETIVRLASEVNREQKKAASCTEEKDKLNQDLLTAVEAKEALEKEVKILQERLLAGQRVWDASKQELSLLKKSSLELEKSCKASLDAAAASQSQYSSFREKIAAHLRGGSGPLKPTEDAILERIREMGSQEESGKQMVTQLEAQISELVEQLGNESGFHQKALQRAQKAENKLETLQGQLTHLEGELVSGDVLRDTLHVEKQKYLQFLDQLSEKMKLDRMAAELGFDMRLEVVLARTEQLVRLESNAVIEHKTIAHNLQRKLKTQKERLESKELHVNLLRQKIAQLEEERQMRSALTVERDEAKVTIRKLQKQVERLQKELSLCRQMNTELKAKLADTNELKIKTLEQTKTIEDLNKSRDTLEKMKEKAEKKLLSVKSELDTAEHEAKENKERAKNMLEVVTSETKTLKKSLEEAEKREKQLVDFREVVSQMLGLNMSSLALPDYEIIKCLERLIHSHQHPFVTCACLKDVPTRQDRHLQGHLQLLH", "length": 721 }, "evidence": [ { "id": "E7F1G2", "url": "https://omabrowser.org/oma/group/E7F1G2/", "database": "OMA" } ], "glygen_name": "Pig", "common_name": "Pig" }, { "uniprot_canonical_ac": "M9NDT0-1", "protein_name": "Coiled-coil domain-containing protein 170", "gene_name": "CG15165", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MPLNPRPTTNGNTPEDWQVFEVLFGADQDPKTIPARMTTMSPLPQPAIPFCQLDTSCSNTGITVTEHHHGLDLTTTLRSELAALSYKKERLTGELAEARAALCSKDADIENLRAQAARQTALIGSLQSRLQNSESREQAVQARCDSTIQTVQREKRSSDERNKELICKIQHLETHMASEESQKEQIKAQLHDLLRRLSITLGMDVCDGNQNSHATPECIISRAEEVMVELQRTKAKVSSTCDTLSSCENELLNLKSLANIEKQRLTAQLDGAGNHNHELEGRCRQYERDLQIQRDRLTESEINGEKLKEELRGFESRCHRLQNNLDRTQGDRLQFLRGLSNLLNVPEPCETLIKDKLREILAENQAMHAQMHSLRDQLNSEHEKLKETQQTTECRLRSGEAQKCELTERLEKCHAEIHTLRKDHMGLSEFLQRLALAMNWGECSAPPALGTDTNLMAENLLERAERLAAHCDHEAPHHHHHHHSPDKGCCDHGHGHGKLRRERSCHDIPLKESSSVYNLQRRVRVLREQVQRRDLHLELLRRKLAIIEDGARGKCMLQGERDEAVCRAKKAAKQVDKLSAQLADARSQIAEVKAQLAEAVEYKITSLERARKIDELTTQICDLEDEKTRLLSQLNALKERLKSSCESNQNRRCRDEALINSMRDDVSRLSSQLSDANQRLSHLQSFRTSVARTLHLRDLPETDLLHRLQALCSAHQEFTMLSKRYETASPVGDHPCPRFDDPIPPSSHCRPPRELSPPPTSFHHKATIHSGSSHHSPPSEHHHGSSSHVHNHHGHGHGHGHSSHSRRQRSKSRDKRLHDECFDTDVHRLHHGCKEELLATGSEDDYDFKSKYC", "length": 853 }, "evidence": [ { "id": "HGNC:21177", "url": "https://alliancegenome.org/gene/HGNC:21177#orthology", "database": "AGR" }, { "id": "MGI:2685067", "url": "https://alliancegenome.org/gene/MGI:2685067#orthology", "database": "AGR" }, { "id": "E7F1G2", "url": "https://omabrowser.org/oma/group/E7F1G2/", "database": "OMA" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q8IYT3-1", "protein_name": "Coiled-coil domain-containing protein 170", "gene_name": "CCDC170", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MSLDCTSHIALGAASPAPEETYDHLSEVPVTREQLNHYRNVAQNARSELAATLVKFECAQSELQDLRSKMLSKEVSCQELKAEMESYKENNARKSSLLTSLRDRVQELEEESAALSTSKIRTEITAHAAIKENQELKKKVVELNEKLQKCSKENEENKKQVSKNCRKHEEFLTQLRDCLDPDERNDKASDEDLILKLRDLRKENEFVKGQIVILEETINVHEMEAKASRETIMRLASEVNREQKKAASCTEEKEKLNQDLLSAVEAKEALEREVKIFQERLLAGQQVWDASKQEVSLLKKSSSELEKSLKASQDAVTTSQSQYFSFREKIAALLRGRLSMTGSTEDTILEKIREMDSREESRDRMVSQLEAQISELVEQLGKESGFHQKALQRAQKAENMLETLQGQLTHLEAELVSGGVLRDNLNFEKQKYLKFLDQLSQKMKLDQMAAELGFDMRLDVVLARTEQLVRLESNAVIENKTIAHNLQRKLKTQKERLESKELHMSLLRQKIAQLEEEKQARTALVVERDNAHLTIRNLQKKVERLQKELNTCRDLHTELKAKLADTNELKIKTLEQTKAIEDLNKSRDQLEKMKEKAEKKLMSVKSELDTTEHEAKENKERARNMIEVVTSEMKTLKKSLEEAEKREKQLADFREVVSQMLGLNVTSLALPDYEIIKCLERLVHSHQHHFVTCACLKDVTTGQERHPQGHLQLLH", "length": 715 }, "evidence": [ { "id": "HGNC:21177", "url": "https://alliancegenome.org/gene/HGNC:21177#orthology", "database": "AGR" }, { "id": "MGI:2685067", "url": "https://alliancegenome.org/gene/MGI:2685067#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-070112-162", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-070112-162#orthology", "database": "AGR" }, { "id": "E7F1G2", "url": "https://omabrowser.org/oma/group/E7F1G2/", "database": "OMA" } ], "glygen_name": "Human", "common_name": "Human" } ], "go_annotation": {}, "pro_annotation": [], "site_annotation": [ { "start_pos": 230, "end_pos": 232, "annotation": "n_glycosylation_sequon" }, { "start_pos": 250, "end_pos": 252, "annotation": "n_glycosylation_sequon" }, { "start_pos": 276, "end_pos": 278, "annotation": "n_glycosylation_sequon" }, { "start_pos": 364, "end_pos": 366, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.oma", "label": "OMA Homologs" }, { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 230, "end_pos": 232 }, { "start_pos": 250, "end_pos": 252 }, { "start_pos": 276, "end_pos": 278 }, { "start_pos": 364, "end_pos": 366 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported_with_glycan", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_predicted", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_automatic_literature_mining", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "phosphorylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "snv_non_disease", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 } ], "sort_fields": [] }, { "table_id": "publication", "table_stats": [ { "field": "total", "count": 0 } ], "sort_fields": [] } ] }, { "uniprot_canonical_ac": "E7F1G4-1", "uniprot_ac": "E7F1G4", "uniprot_id": "E7F1G4_DANRE", "mass": { "chemical_mass": 38338.0, "monoisotopic_mass": 38338.0 }, "refseq": { "ac": "NP_001429332", "name": "R3H and coiled-coil domain-containing protein 1-like", "summary": "", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429332" }, "gene_names": [ { "name": "r3hcc1l", "type": "recommended", "evidence": [ { "id": "E7F1G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1G4" } ] }, { "name": "fc76b11", "type": "synonym", "evidence": [ { "id": "NP_001429332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429332" } ] }, { "name": "r3hcc1l", "type": "synonym", "evidence": [ { "id": "NP_001429332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429332" } ] }, { "name": "wu:fc76b11", "type": "synonym", "evidence": [ { "id": "NP_001429332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429332" } ] } ], "protein_names": [ { "name": "Coiled-coil domain-containing protein R3HCC1L", "type": "synonym", "evidence": [ { "id": "E7F1G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1G4/entry#names_and_taxonomy" } ] }, { "name": "R3H and coiled-coil domain-containing protein 1-like", "type": "synonym", "evidence": [ { "id": "NP_001429332", "database": "RefSeq", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429332" } ] } ], "function": [ { "annotation": "##Evidence-Data-START## Transcript exon combination :: GDQH01023169.1, SRR26395014.28904.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA3505370, SAMEA3505371 [ECO:0000348] ##Evidence-Data-END## VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from JBMGRA010000001.1. On Aug 5, 2025 this sequence version replaced XP_690294.1.", "evidence": [ { "database": "RefSeq", "id": "NP_001429332", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429332" } ] } ], "disease": [], "snv": [], "mutagenesis": [], "expression_tissue": [], "expression_disease": [], "species": [ { "name": "Danio rerio", "taxid": 7955, "evidence": [ { "database": "UniProtKB", "id": "E7F1G4", "url": "https://www.uniprot.org/uniprotkb/E7F1G4" } ], "common_name": "Zebrafish", "glygen_name": "Zebrafish", "reference_species": "Danio rerio [7955]" } ], "gene": [ { "name": "r3hcc1l", "url": "https://www.uniprot.org/uniprotkb/E7F1G4", "locus": {} } ], "crossref": [ { "id": "ZFIN:ZDB-GENE-030131-4156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4156", "database": "AGR", "categories": [ "Protein Classification" ] }, { "id": "ENSDARG00000089243", "url": "https://bgee.org/?page=gene&gene_id=ENSDARG00000089243", "database": "Bgee", "categories": [ "Gene Expression" ] }, { "id": "561802", "url": "https://www.ncbi.nlm.nih.gov/gene/561802", "database": "GeneID", "categories": [ "Genome Annotation" ] }, { "id": "IPR012677", "url": "https://www.ebi.ac.uk/interpro/entry/IPR012677", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR035979", "url": "https://www.ebi.ac.uk/interpro/entry/IPR035979", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR039884", "url": "https://www.ebi.ac.uk/interpro/entry/IPR039884", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "IPR053800", "url": "https://www.ebi.ac.uk/interpro/entry/IPR053800", "database": "InterPro", "categories": [ "Protein Classification" ] }, { "id": "dre:561802", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561802", "database": "KEGG Pathway", "categories": [ "Enzyme and Pathway" ] }, { "id": "YNMDRDD", "url": "https://omabrowser.org/oma/group/YNMDRDD/", "database": "OMA", "categories": [ "Protein Classification" ] }, { "id": "E7F1G4", "url": "https://www.orthodb.org/?gene=E7F1G4", "database": "OrthoDB", "categories": [ "Protein Classification" ] }, { "id": "PTHR21678", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21678", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PTHR21678:SF7", "url": "http://www.pantherdb.org/panther/family.do?clsAccession=PTHR21678:SF7", "database": "PANTHER", "categories": [ "Protein Classification" ] }, { "id": "PF22877", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22877", "database": "Pfam", "categories": [ "Protein Classification", "Other" ] }, { "id": "NP_001429332", "url": "https://www.ncbi.nlm.nih.gov/protein/NP_001429332", "database": "RefSeq", "categories": [ "Protein" ] }, { "id": "E7F1G4", "url": "https://www.uniprot.org/uniprotkb/E7F1G4", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "E7F1G4-1", "url": "https://www.uniprot.org/uniprotkb/E7F1G4-1", "database": "UniProtKB", "categories": [ "Protein" ] }, { "id": "ZDB-GENE-030131-4156", "url": "https://zfin.org/ZDB-GENE-030131-4156", "database": "ZFIN", "categories": [ "Protein", "Organism-specific" ] } ], "sequence": { "sequence": "METEAAQPEQGSKTAVPARTKRPTMEVYVPKKRQAEKTDKPQSDGDKKSKPRPRYTDKARKNKKDKAKVSETQNGEIKPDAGEQGGGGDTENQNTEPEKDEESTGDMNTTSRTVHSPEDSSSVLEHDDEEMKDEEENWDSLFNDDGDCLDPHLMEEMSLKEGRKKQSAQDSGFDYYNWSPQDDEEVELRDDELSHIIEIYDFPTEFKTEDLVRSFSSFQQKGFDITWIDDTHALGLFSSPIAARDALRMKNPMMKVRPLSSSSNATKAKARSCSDYLLPAKERPQTSAALARRLVIGALGVKSNQTREEREAERNKLQQAREQKRLAAKQREDAWEGK", "length": 338, "header": "tr|E7F1G4-1|E7F1G4_DANRE Isoform 1 of Coiled-coil domain-containing protein R3HCC1L OS=Danio rerio OX=7955 GN=r3hcc1l PE=4 SV=1 CANONICAL=E7F1G4-1" }, "isoforms": [ { "isoform_ac": "E7F1G4-1", "url": "https://www.uniprot.org/uniprotkb/E7F1G4/entry#E7F1G4-1", "sequence": { "sequence": "METEAAQPEQGSKTAVPARTKRPTMEVYVPKKRQAEKTDKPQSDGDKKSKPRPRYTDKARKNKKDKAKVSETQNGEIKPDAGEQGGGGDTENQNTEPEKDEESTGDMNTTSRTVHSPEDSSSVLEHDDEEMKDEEENWDSLFNDDGDCLDPHLMEEMSLKEGRKKQSAQDSGFDYYNWSPQDDEEVELRDDELSHIIEIYDFPTEFKTEDLVRSFSSFQQKGFDITWIDDTHALGLFSSPIAARDALRMKNPMMKVRPLSSSSNATKAKARSCSDYLLPAKERPQTSAALARRLVIGALGVKSNQTREEREAERNKLQQAREQKRLAAKQREDAWEGK", "length": 338, "header": "tr|E7F1G4-1|E7F1G4_DANRE Isoform 1 of Coiled-coil domain-containing protein R3HCC1L OS=Danio rerio OX=7955 GN=r3hcc1l PE=4 SV=1 CANONICAL=E7F1G4-1" }, "locus": {} } ], "glycosylation": [], "phosphorylation": [], "glycation": [], "keywords": [], "publication": [], "pathway": [ { "id": "dre:561802", "name": "", "url": "https://www.genome.jp/dbget-bin/www_bget?dre:561802", "resource": "KEGG Pathway" } ], "orthologs": [ { "uniprot_canonical_ac": "A0A0G2JZM0-1", "protein_name": "R3H domain and coiled-coil containing 1-like", "gene_name": "R3hcc1l", "tax_id": 10116, "organism": "Rattus norvegicus", "sequence": { "sequence": "MQQEAERCRVRTKRPDMALYVPKARRGAALLKSGDQEENQGPPAFVLREQKEDCLPQKTSTSKPESHRLSAGQSGRKDSNCREGKRSPPKLRKDRSPPKRNKEKACSKRGTGKPIDASSQEHQNSAHDAAAVSSIPLRRLFKPKEMECVEVQTSGGTGPWGVPPSQSSSEVSAAQVPNRPFQNVELCDFSGETFVNRNLESSIVTEAKVMELVSQFPQVVTTMLKPDGMAMPGTLSSDSETAPYGVETSHGMSKHSPGNISAISVPGEPDDAAHPTFVDFEAESESTVNSTESVLGQNGVDSISETMGNVSLKMAIVSKLESTNGIIDPAVTGECGNDSSADELCVKSEPSDTVDLVHEIDTGNGFRDVCDSASKAGMVDIAGTVCDPVTVGSPCTAAVRESGESSGNMRNSSDYIEMSADVARLDSAKSETNSENSSSLNACSDIYAGSIASGFTASTGKLTESVPDCASSLPIKKTADSDITPCLDSELSMSNGSGILVESALASDLDTTEEMTEALHDLRTAEEFKTKEEDDSESRVCGIPFSDSSVDTSVGLKTTDTSHTQGSIAVEESWESMFNDDGDCVDPRLLQELSGNMKNRKSIQEPRFDYYNHELPDIDLSECEFPHVIEIYDFPQEFRTEDLLRIFCSYQKKGFDIKWVDDTHALGVFSSPIAARDALGIKHTMVKIRPLSQATRAAKAKARACAEFLQPAKERPETSAALARRLVISALGVRSRQSKTEREAELRKLQEARERKRLEAKQREDIWEGRDQSVV", "length": 775 }, "evidence": [ { "id": "HGNC:23512", "url": "https://alliancegenome.org/gene/HGNC:23512#orthology", "database": "AGR" }, { "id": "MGI:1196316", "url": "https://alliancegenome.org/gene/MGI:1196316#orthology", "database": "AGR" } ], "glygen_name": "Rat", "common_name": "Rat" }, { "uniprot_canonical_ac": "E1JIB4-1", "protein_name": "R3H domain-containing protein", "gene_name": "anon-EST:Posey170", "tax_id": 7227, "organism": "Drosophila melanogaster", "sequence": { "sequence": "MDQEFVHNVGCDIELFVKKRLNRGVLLFPPVGNYRRYLIHQTCEKYRQQYDLFTFSVGQGPQRRTVLCFRNQLLDPSGFENRKQQQQREKDREREAARSWRSNNNSHYHTNGRSSSASRRSATELCKMGVKKHISETPLSKSNSVDLYRPPALRNNSNNNNSSSEEAAAVNEAITTPLAAGTATTASTSPTSKESPNREADASAAAAAAATRRERRPDRAVYVPRARRSQTTPPTTTTTTTAAAATAVATTSPPAAAAVVAATITTAPDSPPVADTQPSKADDVNGQPPSKSKKSKSHRERRERAKKTTTATTADNATVLVISASENDTQSNEEHRPAKPADCDKEIMSGAQRTKPGNGNKSASNGKSQASPPLRIEDVVAARSTNGEEPAKCDNDVRELQRASKEINRSNRRIMKQTFNSDVLEIPEKIETSATKAIPTSPQASATAKPPVDSTTEDDDEEDEDDWEKMFDESGDCLDPKLLQELTESVGKCKIELPKMDYTVFHIKQQLLNEEEFPHVLEVSNFPVEFKTPDLLMLFAQYRGSGFDIKWVDDTHALAVFSSSRIAAEVLTMGHPFVKLKPLAEATLESRLKAKKAGAVSMQPYRQRPETCTALARRLVSGALGVKLPTAPQERENERRVLREAKERKLLAAKQRDEVWES", "length": 662 }, "evidence": [ { "id": "HGNC:23512", "url": "https://alliancegenome.org/gene/HGNC:23512#orthology", "database": "AGR" }, { "id": "MGI:1196316", "url": "https://alliancegenome.org/gene/MGI:1196316#orthology", "database": "AGR" } ], "glygen_name": "Fruit fly", "common_name": "Fruit fly" }, { "uniprot_canonical_ac": "Q7Z5L2-1", "protein_name": "Coiled-coil domain-containing protein R3HCC1L", "gene_name": "R3HCC1L", "tax_id": 9606, "organism": "Homo sapiens", "sequence": { "sequence": "MQQESERCRVRARRPDMALYVPKARRGAVLLKTGDEEESCGSPNSVVKEKQKESSLSQKEVFKDKPEARRLNINPDRKEHNCREEKKSSTKLRMDTCLQKTNRVCSKRGTTESKEVLSQGQQQGAPNAGVITNAPLQRHFKPKKVECLEVETTDVTGHERILLSQACLEISEAQVPSKPFQNVEFCDFSRHEPDGEAFEDKDLEGRIETDTKVLEILYEFPRVFSSVMKPENMIVPIKLSSDSEIVQQSMQTSDGILNPSSGGITTTSVPGSPDGVFDQTCVDFEVESVGGIANSTGFILDQKDTDSIPATMGHISLSESTNDTVSPVMIRECEKNDSTADELHVKHEPPDTAVLAHETHRDSGFKNVGDITNKACMMDTTGMSCSDHVTVDSPYVVAVRIADETSINTRSFSKFVGMSADATPLHVARSGNDTEDFSNPSACSDIYGESISSHFTESTGKLIESLSDCASSLPIKKIAGSNYNTFLDSELSMLNGTKVLSDSAVGIDLGSTGDTTEALHELRTAEEFKTEEQDDSGSIEFGVSFPDRESSSMETSIEPKATETSHTEGITAIEESWESMFNDDGDCLDPRLLQEGILMHIKPENHCSKLSGNTKSRESIQEPRSDYYNHEVPDIDLSDCEFPHVIEIYDFPQEFHTEDLLRVFCSYQKKGFDIKWVDDTHALGVFSSPITARDALGIKHTMVKIRPLSQATRAAKAKARAYAEFLQPAKERPETSAALARRLVISALGVRSKQSKTEREAELKKLQEARERKRLEAKQREDIWEGRDQSTV", "length": 792 }, "evidence": [ { "id": "HGNC:23512", "url": "https://alliancegenome.org/gene/HGNC:23512#orthology", "database": "AGR" }, { "id": "MGI:1196316", "url": "https://alliancegenome.org/gene/MGI:1196316#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4156#orthology", "database": "AGR" } ], "glygen_name": "Human", "common_name": "Human" }, { "uniprot_canonical_ac": "Q8BJM3-1", "protein_name": "Coiled-coil domain-containing protein R3HCC1L", "gene_name": "R3hcc1l", "tax_id": 10090, "organism": "Mus musculus", "sequence": { "sequence": "MQQEAERCRVRTKRPDMALYVPKARRGTALLKSSDQEEGHGPPAFVPKDQKEGCLPQKISASKPESQRRGAGHSDRKDVDCREGKRSASQLRKDRCPQKQNKEKACSKKGAEESTEASSQEHQHRAPDAGIVSSIPLQRLFKPKDMDCWEVQTAGATGHWRVSPSQSSSEVSAAQVPSRPFQNVELCDFSGETFVNRNLESSIVTEAKVPELVSQFPQVVTTLLKPDGMAMPVTLSSDSETAPSSLETPDGMSKHSPGDISVVSVPGGPDEDVDSTFVDFEVESEGTVNSTESVLGQKGVDSILETVDNVSLKMAVVSKLESTNGTIDPAVTRECESDSSADELCVKSEPSDTAVLVHEIDTDDGFRNVCDSTSKACMVDIAGTACDPVTEGSSCTGAVGESGESSGNMRNFSDYIEMSADVAPLDRAKSENDSENISSLSACSDIYAESIASGFTESTGKLIESVSDGASSLPIKKTADSNIATCLDSELSMSDASDVLLESALGSDLDTTEEMTEALHDLKTAEEFKTKEEDYSESVVCGISFSDSSVETSVDLKTTDTSHIQGSSAVEESWESMFNDDGDCVDPRLLLELSGNVKNRKSIQEPRFDYYSHELPDIDLSECEFPHVIEIYDFPQEFRTEDLLRIFCSYQKKGFDIKWVDDTHALGVFASPITARDALGTKHTMVKIRPLSQATRAAKAKARACAEFLQPAKERPETSAALARRLVISALGVRSKQSKTEREAELRKLQEARERKRLEAKQREDIWEGRDQSVV", "length": 775 }, "evidence": [ { "id": "HGNC:23512", "url": "https://alliancegenome.org/gene/HGNC:23512#orthology", "database": "AGR" }, { "id": "MGI:1196316", "url": "https://alliancegenome.org/gene/MGI:1196316#orthology", "database": "AGR" }, { "id": "ZFIN:ZDB-GENE-030131-4156", "url": "https://alliancegenome.org/gene/ZFIN:ZDB-GENE-030131-4156#orthology", "database": "AGR" } ], "glygen_name": "Mouse", "common_name": "Mouse" } ], "go_annotation": { "categories": [ { "name": "Molecular Function", "total": 1, "go_terms": [ { "name": "nucleic acid binding", "id": "GO:0003676", "url": "https://www.ebi.ac.uk/QuickGO/term/GO:0003676", "evidence": [ { "database": "UniProtKB", "id": "E7F1G4", "url": "https://www.uniprot.org/uniprotkb/E7F1G4" } ], "pmid": "" } ] } ] }, "pro_annotation": [], "site_annotation": [ { "start_pos": 108, "end_pos": 110, "annotation": "n_glycosylation_sequon" }, { "start_pos": 177, "end_pos": 179, "annotation": "n_glycosylation_sequon" }, { "start_pos": 264, "end_pos": 266, "annotation": "n_glycosylation_sequon" }, { "start_pos": 304, "end_pos": 306, "annotation": "n_glycosylation_sequon" } ], "ptm_annotation": [], "interactions": [], "reactions": [], "reaction_participants": [], "reaction_enzymes": [], "biomarkers": [], "structures": [], "lectin_list": [], "domain_list": [ { "evidence": [ { "id": "E7F1G4", "database": "UniProtKB", "url": "https://www.uniprot.org/uniprotkb/E7F1G4" }, { "id": "PF22877", "database": "Pfam", "url": "https://www.ebi.ac.uk/interpro/entry/pfam/PF22877" } ], "ann_type": "Domain_Extent_Annotation", "uniprotkb_annotation": "Thc1 RRM", "eco_id": "ECO_0000259", "start_pos": 198, "end_pos": 246, "start_aa": "Glu", "end_aa": "Ala", "glycosite_overlap": "" } ], "binding_sites": [], "synthesized_glycans": [], "enzyme_annotation": [], "cluster_types": [ { "name": "homologset.agr", "label": "AGR Homologs" } ], "sequence_features": { "n_linked_sites": [], "o_linked_sites": [], "snv_sites": [], "glycation_sites": [], "phosphorylation_sites": [], "sequon_annotation_sites": [ { "start_pos": 108, "end_pos": 110 }, { "start_pos": 177, "end_pos": 179 }, { "start_pos": 264, "end_pos": 266 }, { "start_pos": 304, "end_pos": 306 } ] }, "class_list": [], "section_stats": [ { "table_id": "glycosylation", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { "table_id": "glycosylation_reported", "table_stats": [ { "field": "total", "count": 0 }, { "field": "total_sites", "count": 0 }, { "field": "n_linked_sites", "count": 0 }, { "field": "o_linked_sites", "count": 0 }, { "field": "n_linked_glycan_sites", "count": 0 }, { "field": "o_linked_glycan_sites", "count": 0 }, { "field": "n_linked_glycans", "count": 0 }, { "field": "o_linked_glycans", "count": 0 }, { "field": "total", "count": 0 } ], "sort_fields": [] }, { 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This record is derived from a genomic sequence (NC_133189) annotated using gene prediction method: Gnomon, supported by mRNA evidence. Also see: Documentation of NCBI's Annotation Process On Mar 30, 2010 this sequence version replaced XP_001332975.1. 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